<?xml version="1.0" encoding="UTF-8"?>
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<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7M9Q2</accession>
    <name>A0A1C7M9Q2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_11884</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01002637">
        <property type="protein sequence ID" value="OBZ71754.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7M9Q2"/>
    <dbReference type="STRING" id="101091.A0A1C7M9Q2"/>
    <dbReference type="InParanoid" id="A0A1C7M9Q2"/>
    <dbReference type="OrthoDB" id="2288827at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040521">
        <property type="entry name" value="KDZ"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33096:SF1">
        <property type="entry name" value="CXC1-LIKE CYSTEINE CLUSTER ASSOCIATED WITH KDZ TRANSPOSASES DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33096">
        <property type="entry name" value="CXC2 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18758">
        <property type="entry name" value="KDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="176"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ71754.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="176" mass="19665" checksum="6BF552289430D50E" modified="2016-11-30" version="1" fragment="single">RLVLFAKDKVSKTYDIEALETCLGCEDAERKLVSLNGNFQLKHCEDALPGIAIEEGMLTPSAFQSSLWGPQSEVLAFEDVNTEKEDCILEEIEDSVFKANGNNNRNTSTSRYDENGVFSMSCAIHGVPERLYNIHGGEGHKYALACVHQMLNTQKDGHNKQFGIMYDIVCMVKKNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MGQ6</accession>
    <name>A0A1C7MGQ6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Iron transport multicopper oxidase FET5</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">FET5</name>
        <name evidence="5" type="ORF">A0J61_11873</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the multicopper oxidase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01002621">
        <property type="protein sequence ID" value="OBZ76002.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MGQ6"/>
    <dbReference type="STRING" id="101091.A0A1C7MGQ6"/>
    <dbReference type="InParanoid" id="A0A1C7MGQ6"/>
    <dbReference type="OrthoDB" id="2121828at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033573">
        <property type="term" value="C:high-affinity iron permease complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005507">
        <property type="term" value="F:copper ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004322">
        <property type="term" value="F:ferroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010106">
        <property type="term" value="P:cellular response to iron ion starvation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033215">
        <property type="term" value="P:reductive iron assimilation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd13899">
        <property type="entry name" value="CuRO_3_Fet3p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.420">
        <property type="entry name" value="Cupredoxins - blue copper proteins"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011706">
        <property type="entry name" value="Cu-oxidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045087">
        <property type="entry name" value="Cu-oxidase_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033138">
        <property type="entry name" value="Cu_oxidase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002355">
        <property type="entry name" value="Cu_oxidase_Cu_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008972">
        <property type="entry name" value="Cupredoxin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11709:SF361">
        <property type="entry name" value="IRON TRANSPORT MULTICOPPER OXIDASE FET3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11709">
        <property type="entry name" value="MULTI-COPPER OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07731">
        <property type="entry name" value="Cu-oxidase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49503">
        <property type="entry name" value="Cupredoxins"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00079">
        <property type="entry name" value="MULTICOPPER_OXIDASE1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00080">
        <property type="entry name" value="MULTICOPPER_OXIDASE2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Plastocyanin-like" evidence="4">
        <location>
            <begin position="125"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="322"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF07731"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OBZ76002.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="322" mass="35877" checksum="23FC34033AD47D00" modified="2016-11-30" version="1" fragment="single">VLTQPTIRSSVYLSAGQRVSVLIKTKQTTEFNYYLHADMDPDMLDTLPDDLHPNITAPVYYDTLHGSFKRVAPITEDHYSKDDALIAPWKETAVLIPDLQINMTMDFMVNTDGLNHGVINNIPYLPPLVPTLHTLLSTGDLANNTRVYGPQSQAYVFQLNQVIEIVLNNLDDGMHPFHLHGHVFQVIARGEGVYGNQTIHDPIYPTVRDTITVPANGYLILRFKADNPGVWFFHCHVDWHLPAGLAATFITAPELVQQQTRLPSSFDHLCHDANMPSRGNAAGKEGLDLEGAPDGIRPVVKEKMFLAGWMATLVGLSSILWH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MTX8</accession>
    <name>A0A1C7MTX8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Peptidase A2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_11640</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01002287">
        <property type="protein sequence ID" value="OBZ80311.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MTX8"/>
    <dbReference type="STRING" id="101091.A0A1C7MTX8"/>
    <dbReference type="InParanoid" id="A0A1C7MTX8"/>
    <dbReference type="OrthoDB" id="5597136at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004190">
        <property type="term" value="F:aspartic-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00303">
        <property type="entry name" value="retropepsin_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.70.10">
        <property type="entry name" value="Acid Proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001969">
        <property type="entry name" value="Aspartic_peptidase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021109">
        <property type="entry name" value="Peptidase_aspartic_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13975">
        <property type="entry name" value="gag-asp_proteas"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50630">
        <property type="entry name" value="Acid proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00141">
        <property type="entry name" value="ASP_PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0064">Aspartyl protease</keyword>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0645">Protease</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="17"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="30"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="278"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022750"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ80311.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="278" mass="31645" checksum="A416E24306CEB33F" modified="2016-11-30" version="1" fragment="single">MIINTLRTNGLLDEEQYTQNSSSYANTTESESEYDSTYEDSDYEVDSTESEINDTDDESESQIRYPFVAEEMRQAQPCRVLIVINDQPVEAVLDTGAAVSVMSVRLARKLNITPDTKESIPLSGFASQGKVVNCKVATDVDVRIGGKLRREHFCIDETQHARDTCLLGRPWIKQHDIRLINRGTIIVVPTKNGHDNIEVQCLMDTEYSNYKDDQQNNIPIYSVQLYNVNSPPKIETGNRRLVEVKSYQEDIVSQSEFLKDVLPEDNEELQVETKELIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MU21</accession>
    <name>A0A1C7MU21_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_11611</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01002252">
        <property type="protein sequence ID" value="OBZ80340.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MU21"/>
    <dbReference type="InParanoid" id="A0A1C7MU21"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="166"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="2"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="176"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="227"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ80340.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="227" mass="25482" checksum="46F16F98009119B6" modified="2016-11-30" version="1" fragment="single">MSQDTQAKLDLILSKLDELNERLQRLESQQNIAEAGKKRGTSVIPFPSYLDEQRGKMKKLIVSTKLIKRALEDTEGNENTEVAYKIFQQACFTQASDMVHRVYLNKPVSWSKVTMSFRLNAVDKANVSIKAITKYDPANFEDNWAVLHLVRRAYSNNASEKVIEERMSSLAKEAPSEEEVPEQDAIDDTSSETSEPSSSEDEEEAPVSLKRKSVSSPVPLGLSKKKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MUG3</accession>
    <name>A0A1C7MUG3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_11426</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01002021">
        <property type="protein sequence ID" value="OBZ80525.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MUG3"/>
    <dbReference type="InParanoid" id="A0A1C7MUG3"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="68"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="70"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="183"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ80525.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="183" mass="21076" checksum="01ED331D5FE90EC9" modified="2016-11-30" version="1" fragment="single">MRYCTICDTRITERAYKKHCDKHELNRIANMVSATMRTAQNYTAYVPDKVDPSEDALMTESEVLPVVDNATDDQSNDEDESCEAVEAEEEAAIDQDQDDQEEEKVNEIEQVNLHLERHLENTDRPLKIDFSSTSGSQNAFDKLNIELKMFMRENKVNNVAQDGLIKHFNKFLRSIGYCTYLIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MV60</accession>
    <name>A0A1C7MV60_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">C-factor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">csgA_1</name>
        <name evidence="3" type="ORF">A0J61_11612</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01002254">
        <property type="protein sequence ID" value="OBZ80339.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MV60"/>
    <dbReference type="InParanoid" id="A0A1C7MV60"/>
    <dbReference type="OrthoDB" id="9876299at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051468">
        <property type="entry name" value="Fungal_SecMetab_SDRs"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43544:SF36">
        <property type="entry name" value="CHAIN OXIDOREDUCTASE (CSGA), PUTATIVE (AFU_ORTHOLOGUE AFUA_4G00910)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43544">
        <property type="entry name" value="SHORT-CHAIN DEHYDROGENASE/REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ80339.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="130" mass="13837" checksum="CA453B6C4EDE00DD" modified="2016-11-30" version="1" fragment="single">NVCGTSDATQAFLPLLRKRGKDSVKKVLNISSILGSIAKINEINSTGGTVEYNVSKTALNMLTRTTAQVLAEENFIVYASHPGWVKTDMGGDDAPVEPTDSVAGQLAKLESATSKDNGGYFDFQGNALPW</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MV66</accession>
    <name>A0A1C7MV66_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_11189</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001760">
        <property type="protein sequence ID" value="OBZ80761.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MV66"/>
    <dbReference type="InParanoid" id="A0A1C7MV66"/>
    <dbReference type="OrthoDB" id="10571879at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ80761.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="70" mass="8054" checksum="6C24AD664A084702" modified="2016-11-30" version="1" fragment="single">YDKNELCSSDQIICIKDVTVKLEDWRDATLNFKVQYASVWSANNNATLHGVFSNAGYTYELHCLYPLFES</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MV68</accession>
    <name>A0A1C7MV68_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_11219</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001791">
        <property type="protein sequence ID" value="OBZ80732.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MV68"/>
    <dbReference type="InParanoid" id="A0A1C7MV68"/>
    <dbReference type="OrthoDB" id="10044727at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="55"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="56"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ80732.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="150" mass="17262" checksum="1317C379D806A9E4" modified="2016-11-30" version="1">MKEDLVLNLIEVQDENPVTQGEDFDFLDNNDAQHWIEIDGAYDLKKPYKKYTVEISEDKEQSKESEEKQDGESSMNRAAIEKISLTLVPVLNAKSEIAKIEFYMILKLMATKHYFNGILSGKSLVKASNDAAMEVWHTPSKYYRPKAIRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MVL5</accession>
    <name>A0A1C7MVL5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_11153</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001718">
        <property type="protein sequence ID" value="OBZ80798.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7MVL5"/>
    <dbReference type="InParanoid" id="A0A1C7MVL5"/>
    <dbReference type="OrthoDB" id="2286841at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31912">
        <property type="entry name" value="IP13529P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31912:SF34">
        <property type="entry name" value="NOTOCHORD-RELATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="unsure residue" description="D or N" evidence="1">
        <location>
            <position position="106"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="424"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ80798.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="424" mass="48069" checksum="E3E6E73D9BA787FB" modified="2016-11-30" version="1" fragment="single">MYSAADNQDVLVVAPLFWIEADSPCHSQLCGLLNPSTKFPCRKCYICLHRRGVSRLEPRDYYIRDHIRRTRAHYELAAETPNRSRMIQGATEDNKDYPASKLSFXDRGSDSLLALNAFSPDKDTPTEILHTVLLGIAQYLTSDLIKVVANDEELNIIADALDNYKSSEGFSRKFSRQLRHCGSFLGRDYKILLQVLPVILVSHSSESTTHIAKIVPCFAKLGKLCSLLFVQEVSDSFDDYIEQVKGSSDKLVLALHLYDTVCTVQDHKGYTAKPKVHFLTHIAEDIQRFGTALNFETEKGEQFNKHIREHIHHTNKVDVSKQPATKFSKQSVMRHVIDGGSWLDDEKKRVQTGDQVWSLIEKHSGEFYHNLFGGSRNLADNNETGYILPAAKESMYACFKRKDAFGVESLLVGQIRNSMIHQFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MWB4</accession>
    <name>A0A1C7MWB4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Protein pim1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">pim1_0</name>
        <name evidence="5" type="ORF">A0J61_10775</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001384">
        <property type="protein sequence ID" value="OBZ81175.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MWB4"/>
    <dbReference type="FunCoup" id="A0A1C7MWB4">
        <property type="interactions" value="872"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7MWB4"/>
    <dbReference type="InParanoid" id="A0A1C7MWB4"/>
    <dbReference type="OrthoDB" id="61110at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000785">
        <property type="term" value="C:chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005085">
        <property type="term" value="F:guanyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006997">
        <property type="term" value="P:nucleus organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016973">
        <property type="term" value="P:poly(A)+ mRNA export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006606">
        <property type="term" value="P:protein import into nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000054">
        <property type="term" value="P:ribosomal subunit export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.30">
        <property type="entry name" value="Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051553">
        <property type="entry name" value="Ran_GTPase-activating"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058923">
        <property type="entry name" value="RCC1-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009091">
        <property type="entry name" value="RCC1/BLIP-II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000408">
        <property type="entry name" value="Reg_chr_condens"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45982">
        <property type="entry name" value="REGULATOR OF CHROMOSOME CONDENSATION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45982:SF1">
        <property type="entry name" value="REGULATOR OF CHROMOSOME CONDENSATION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25390">
        <property type="entry name" value="WD40_RLD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00633">
        <property type="entry name" value="RCCNDNSATION"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50985">
        <property type="entry name" value="RCC1/BLIP-II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00626">
        <property type="entry name" value="RCC1_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50012">
        <property type="entry name" value="RCC1_3"/>
        <property type="match status" value="7"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0344">Guanine-nucleotide releasing factor</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="RCC1" evidence="3">
        <location>
            <begin position="39"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="domain" description="RCC1-like" evidence="4">
        <location>
            <begin position="40"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="repeat" description="RCC1" evidence="3">
        <location>
            <begin position="92"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="repeat" description="RCC1" evidence="3">
        <location>
            <begin position="142"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="repeat" description="RCC1" evidence="3">
        <location>
            <begin position="197"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="repeat" description="RCC1" evidence="3">
        <location>
            <begin position="250"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="repeat" description="RCC1" evidence="3">
        <location>
            <begin position="311"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="repeat" description="RCC1" evidence="3">
        <location>
            <begin position="379"/>
            <end position="432"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022658"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF25390"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OBZ81175.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="432" mass="46762" checksum="B8425902092874BB" modified="2016-11-30" version="1">MTDASQPSSLKRARSSENVYAKKSRHIANQIVKAPTQVGKVFVFGTGDTGQLGLGDEMLERKKPMPLNAFDNDQIVDVVSGGMHSIAITSEGKLWSWGCNDQRALGRSGEEYEPARVEGMDDVRVVKVACCDSVTMALSDEGKLYCWGTYRCAEGPLGFSRNKAVQETPAIFEPFAKVQIADIAAGTDHCLALSRDGRVFVWGNGQQFQLGRRIMERHLINGLRPEALNLKNIKLIGTGSYHSFAVSHDNTLYVWGLNNFQQCGLVDSEENNEPAPNVITKPTVVKALEGKGAIKDVQGGEHHSLVLMEDGTVYAFGRADSDQLGLPADLIDKVQTREEGADVSNFKRAVGLPTLIPNLNNVVSISTGTNHSIALTSEGKAYTWGFGECYALGNGSSDDEPIPVELTGQKLEGHKVIRISAGAQHSMVLATE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MWM7</accession>
    <name>A0A1C7MWM7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Calcium-binding protein 7</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">Cabp7</name>
        <name evidence="5" type="ORF">A0J61_10667</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001300">
        <property type="protein sequence ID" value="OBZ81285.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MWM7"/>
    <dbReference type="STRING" id="101091.A0A1C7MWM7"/>
    <dbReference type="InParanoid" id="A0A1C7MWM7"/>
    <dbReference type="OrthoDB" id="26525at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032588">
        <property type="term" value="C:trans-Golgi network membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00051">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.238.10:FF:000178">
        <property type="entry name" value="Calmodulin-2 A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051111">
        <property type="entry name" value="Ca-binding_regulatory"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46311">
        <property type="entry name" value="CALCIUM-BINDING PROTEIN 8-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46311:SF5">
        <property type="entry name" value="EF-HAND DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13499">
        <property type="entry name" value="EF-hand_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00054">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0106">Calcium</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="EF-hand" evidence="4">
        <location>
            <begin position="16"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="4">
        <location>
            <begin position="52"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="86"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="100"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="123"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OBZ81285.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="123" mass="14307" checksum="568538968608D000" modified="2016-11-30" version="1" fragment="single">MSNKPSLSRNSSITDEELKSLKEAFALYDADHNGFIKLSQFGDILKSLNIEHDAKKLETIVKKSDKNHDGRIDFDEFVSVMTHFLPPQYTDEPEQVEEANDNKNRTRDINSNRQKSRERYSRC</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MWP2</accession>
    <name>A0A1C7MWP2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_10730</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001349">
        <property type="protein sequence ID" value="OBZ81221.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MWP2"/>
    <dbReference type="STRING" id="101091.A0A1C7MWP2"/>
    <dbReference type="InParanoid" id="A0A1C7MWP2"/>
    <dbReference type="OrthoDB" id="2256709at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="26"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="218"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="26"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="218"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="262"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="284"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="301"/>
            <end position="311"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ81221.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="311" mass="35073" checksum="F6C4CA439DA1D1F4" modified="2016-11-30" version="1">MTPDEEMQQMPQQLAETQNMLSQLIEQQQQQYEAQAADTSDPVDNLQSHLHPSGMRPRFDWTPDLLVQDQFALDRDLFNNEVLSDEARGELINKFPPIRQLNYQPPLTMPEAKRRMNTSQTKEDATFKHNQYLLSGTFRPLNILASEIRTTDLPNEHSQRFIEIINDIRSLMLNINASASSSRTDIAFRAVNPHFRAPSAGHQNYLMTSEAFQSAVSQQATANITTREASSRGKRSGSQSSSHSNVGKNNPFFREGPSMCQGGYSNNSGNNSGNNSGPRPHKPSFSQRQNTNPFVKNTHFNAKKQKLPAPW</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MXU5</accession>
    <name>A0A1C7MXU5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Choice-of-anchor A domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_10297</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001108">
        <property type="protein sequence ID" value="OBZ81653.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MXU5"/>
    <dbReference type="STRING" id="101091.A0A1C7MXU5"/>
    <dbReference type="InParanoid" id="A0A1C7MXU5"/>
    <dbReference type="OrthoDB" id="2280597at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026588">
        <property type="entry name" value="Choice_anch_A"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR04215">
        <property type="entry name" value="choice_anch_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20597">
        <property type="entry name" value="pAdhesive_15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008889356" description="Choice-of-anchor A domain-containing protein" evidence="1">
        <location>
            <begin position="27"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="domain" description="Choice-of-anchor A" evidence="2">
        <location>
            <begin position="57"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="417"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF20597"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ81653.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="417" mass="43659" checksum="08C55166D766E24B" modified="2016-11-30" version="1" fragment="single">MPRCQKMVNKTAAFLLLGAIASEVLASTNFSSNSRSVFNKRSESDWVCSSDDTPSLMLTHFAAVFFGDFTTTGGQDILGPLAVGGKFTANHYTVNANQSPKCSDGANNIKDYALVVDGKVDADEVRLKGNAQVPEGSTGLVETIDTCKVYKGGKSIYDFNLARQNALSASETFARMRPNMILRSDGTLSSLRESVDGFHVLTFSTCNEGSCDLIPGQMSDPSALLQGKGNWNGPKGMSWPKTGTLVLNIPVESGSTFTLLGNLVTQGMDPCRTIFNFYSSKNGGISSGSFTLKRHTGSNLGAFVLAPRANIIDGSTGAFAGTVVGNNYSWGGSGIEIHNYKAAGGSCDTFEGCLPIVPPKKTTTTSTAATTTTTSIKGATPTTSTTAAVPTTTCTKSTCKNTTTTAAVPTTTCTKST</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MXU9</accession>
    <name>A0A1C7MXU9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Transposase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_10742</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001360">
        <property type="protein sequence ID" value="OBZ81209.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MXU9"/>
    <dbReference type="InParanoid" id="A0A1C7MXU9"/>
    <dbReference type="OrthoDB" id="2289199at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004242">
        <property type="entry name" value="Transposase_21"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46579:SF2">
        <property type="entry name" value="C2H2-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46579">
        <property type="entry name" value="F5/8 TYPE C DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02992">
        <property type="entry name" value="Transposase_21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="870"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ81209.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="870" mass="100220" checksum="79B824CB1C765028" modified="2016-11-30" version="1" fragment="single">MHQDRENAKKPRIESPSSFQALTSGVTFAFNDLLVEEDEGFSFGETPLEVASFATIQAESAVQDEHRFKNPRSSYLPNSSIASLLFALLLCLRKNQLTDAACETVMLFCNMVLCLTEESFRFPMSIATFDRWCSSNHYGNTGIKEYASCTSCHAIHRYETDEDKGKVQDQVYCNDAGIFAGSSMCQNKLLDCNQYGTITPSRSFFYNSLVDTLKMFFMRNGFVESITRWKKTQTEHDVLSDIYDGHAPFVDEDDFNLLFTLNCDWFQAYKDPYSIGAIYLTIQNLPREIRNLRTNTILVCLINGPKEPKTYEMNRYLRPLVKELLVLMNGVDTPTRKHGVKVVKGALSLYRMDLPAQRKVAGFTSYNFINACHKCKKQFDSIIAGDKTRDFTDFNTDNWVKRSRVEHRQYAAEWLNTKTDSERNQKDRENGTRWSVLLDLPYFDPIRHVGVDTMHNLLLGITKKMALIWIGVAPSRNSSLPIMLSLGDLKEMQVILETKLVLPSGHAVSSIARKLPIGKGFSNFKAEEWATWLLVLSPYLLAQRLTTEAYDLWMLLVKAFRIFLSPSLTMSELDEAQKLKKAFLVGFEAVYDDKFLITPNFHNALHLKETILDYSASPSHWLFNFERYNQDIKGIRTNRKSCVERTYMEQFLMQVHSEDNAESLLDAIPAEFKETVQDQFSCQKTRCDESLLEEYTLSCNDFFLSNFNQFITGTEYAYGFEQLPPKAYLSMSLKLDKLSTDVFTCLVEYYNSVYCTTYVDAQISFGNPGSLPVDWHASKFKTIDILGNKYTSIAASRLKNRGSYALAYYQNDDGTTLRYCQIYRMLRHTITVEEDDGFRASQVHTLAYVKWFTKSDMRFHYYNNVDFQKY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MY58</accession>
    <name>A0A1C7MY58_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Methyltransferase-like protein 4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">METTL4</name>
        <name evidence="3" type="ORF">A0J61_10614</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the MT-A70-like family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001271">
        <property type="protein sequence ID" value="OBZ81336.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MY58"/>
    <dbReference type="FunCoup" id="A0A1C7MY58">
        <property type="interactions" value="24"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7MY58"/>
    <dbReference type="InParanoid" id="A0A1C7MY58"/>
    <dbReference type="OrthoDB" id="61116at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007757">
        <property type="entry name" value="MT-A70-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12829:SF4">
        <property type="entry name" value="N(6)-ADENINE-SPECIFIC METHYLTRANSFERASE METTL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12829">
        <property type="entry name" value="N6-ADENOSINE-METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05063">
        <property type="entry name" value="MT-A70"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51143">
        <property type="entry name" value="MT_A70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="36"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="37"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00489"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ81336.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="417" mass="48065" checksum="C4D5CB09EEFF23C4" modified="2016-11-30" version="1">MFDLIDSEKCFSKGISPYKLISGEFDVCSPYFQAKKRSTEPPHKRQKSNTERETEERHQTIRTQLVACLDQLAEQWPANWKERQTPTTQDTETETVDFPSMQQMVEMAQLKFSFESDKEEECVAIELEDQTIDLFSVFGTVYRNSSDDVRWLPLTMTANYLIPPHSTFLMGSMLNTIDLLGNYVETIGGADLIVMDPPWPNKSVHRSSHYDTQDIYDLYKIPMLKLISKRDSLVAIWVTNKPKFRKFMIDKLLPAWQLRCVAEWVWLKTTTQAESVCPLDSTHKKPYEQLILARPIHSPSPPSMPKTHTLVSVPSTTTQAESVCPLDSTHKKPYEQLILARPIHSPSPPSMPKTHTLVSVPSVRHSRKPPLEDVLLPWIDQQEPVCLELFARCLMPGWISWGNECLRFQHANYFQKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MYU9</accession>
    <name>A0A1C7MYU9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Negative regulator of sexual conjugation and meiosis</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">ran1_0</name>
        <name evidence="6" type="ORF">A0J61_10000</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the protein kinase superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000998">
        <property type="protein sequence ID" value="OBZ81952.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MYU9"/>
    <dbReference type="STRING" id="101091.A0A1C7MYU9"/>
    <dbReference type="InParanoid" id="A0A1C7MYU9"/>
    <dbReference type="OrthoDB" id="541276at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010506">
        <property type="term" value="P:regulation of autophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045269">
        <property type="entry name" value="Atg1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24348">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE UNC-51-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24348:SF68">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE ATG1C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3 4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="1 3 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="5">
        <location>
            <begin position="24"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="53"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OBZ81952.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="315" mass="36059" checksum="BE675041BD11645F" modified="2016-11-30" version="1">MPRFHQSQLNPYSLLNSYIDNQSIQLIGILGVGAYGIIYLGQNTVTSQQVAIKLLTHLSRREAEIHAYLSRHPNILSFEKLVYEDHKMFMILEYRPEGDLFSAITKNRKGIVGNNDSIRHIFLQIIDGVQFCHQHQIAHRDLKPENIMLGPELSIKLTDFGLATTQSISTEFGCGSTFYFSPECQGNNRNGYDTQKNDIWSLGVILINLTAGRNPWKQATLNNPAYAAYLRHPGQFFKTILPCISSELESILLDIFCLDPDQRITLAKLRLRIEQCTRFVQPISRPIDRYHPYSHPYKSLKVVNHENCFLKPSLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MYV1</accession>
    <name>A0A1C7MYV1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Translation initiation factor RLI1</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">ATP-binding cassette sub-family E member RLI1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">Abce1</name>
        <name evidence="8" type="ORF">A0J61_09918</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Component of the multifactor complex (MFC) involved in translation initiation. Required for the binding of MFC to the 40S ribosome. Required for the processing and nuclear export of the 60S and 40S ribosomal subunits.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000972">
        <property type="protein sequence ID" value="OBZ82030.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MYV1"/>
    <dbReference type="FunCoup" id="A0A1C7MYV1">
        <property type="interactions" value="918"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7MYV1"/>
    <dbReference type="InParanoid" id="A0A1C7MYV1"/>
    <dbReference type="OrthoDB" id="6593433at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005852">
        <property type="term" value="C:eukaryotic translation initiation factor 3 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045727">
        <property type="term" value="P:positive regulation of translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042273">
        <property type="term" value="P:ribosomal large subunit biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000054">
        <property type="term" value="P:ribosomal subunit export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032790">
        <property type="term" value="P:ribosome disassembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006413">
        <property type="term" value="P:translational initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006415">
        <property type="term" value="P:translational termination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd03236">
        <property type="entry name" value="ABC_RNaseL_inhibitor_domain1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000144">
        <property type="entry name" value="ATP-binding cassette sub-family E member 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000152">
        <property type="entry name" value="ATP-binding cassette, sub-family E, member 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017896">
        <property type="entry name" value="4Fe4S_Fe-S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017900">
        <property type="entry name" value="4Fe4S_Fe_S_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013283">
        <property type="entry name" value="RLI1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034348">
        <property type="entry name" value="RLI_dom_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007209">
        <property type="entry name" value="RNaseL-inhib-like_metal-bd_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF009945">
        <property type="entry name" value="PRK13409.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19248">
        <property type="entry name" value="ATP-BINDING TRANSPORT PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00037">
        <property type="entry name" value="Fer4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04068">
        <property type="entry name" value="Fer4_RLI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01868">
        <property type="entry name" value="ABCEFAMILY"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54862">
        <property type="entry name" value="4Fe-4S ferredoxins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00198">
        <property type="entry name" value="4FE4S_FER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51379">
        <property type="entry name" value="4FE4S_FER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="7">
        <location>
            <begin position="46"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="6">
        <location>
            <begin position="70"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="6">
        <location>
            <begin position="342"/>
            <end position="562"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00056499"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00067238"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00082546"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OBZ82030.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="599" mass="67487" checksum="E03886233A50664E" modified="2016-11-30" version="1">MSDKLTRIAIVSADKCKPKKCRQECKRSCPVNRMGKLCIEVESTSKIAWISEELCIGCGICVKKCPFGAIHIINLPTNLEGEVTHRYSANSFKLHRLPVPRPGQVLGLVGTNGIGKSTALKILSGKMKPNLGKFDAPPDWQDILKYFRGSELQNYFTKILEDNLKAIIKPQYVDHIPKVVSGKVQQLLQDKHERNNFEEMIDMLDLKDVLQREVGQLSGGELQRFAIAVVAVQQADVYMFDEPSSYLDVKQRLNAARVIRSLLSSETYIICVEHDLSVLDYLSDYVCILYGKPSAYGVVTLPYSVREGINIFLDGNIPTENLRFREESLTFKIAETAQEVTVSKVNTYKYPKMEKQLGDFKLTVEAGEFQDSEIIVMLGQNGTGKSTFIRLLAGLLKPDGQGKVPQLNVSYKPQKISPKFQGTVRMLFLKKIKGAFLNPQFNTDVIKPLNIENIIDQEVMHLSGGELQRVAIVLALGQPADIYLIDEPSAYLDSEQRIIAAKVIKRFIIHFKRTAFIVEHDFIMGTYLADRVVVYEGTPSVEAVANTPQSLLTGMNKFLASLEITFRRDPTNYRPRINKLDSQLDQEQKSSGNYFFLEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MZL0</accession>
    <name>A0A1C7MZL0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_11378</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001969">
        <property type="protein sequence ID" value="OBZ80574.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MZL0"/>
    <dbReference type="InParanoid" id="A0A1C7MZL0"/>
    <dbReference type="OrthoDB" id="2263388at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ80574.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="94" mass="11062" checksum="3E94D18D3C88BF55" modified="2016-11-30" version="1">MGCYLYESDDDSDKMQCPVCKEPRSVSKKTYVKYMSIAKKIAQLLALLDKRQKLEYRSETFGQNADLQGEYFDIFCGEFYQDMKQDQKFTLPLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MZM0</accession>
    <name>A0A1C7MZM0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">ATP-dependent DNA helicase</fullName>
            <ecNumber evidence="1">5.6.2.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">pif1_0</name>
        <name evidence="7" type="ORF">A0J61_09640</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="5.6.2.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the helicase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.6.2.3" evidence="1"/>
    <dbReference type="EMBL" id="LUGH01000897">
        <property type="protein sequence ID" value="OBZ82310.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7MZM0"/>
    <dbReference type="InParanoid" id="A0A1C7MZM0"/>
    <dbReference type="OrthoDB" id="2287865at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043139">
        <property type="term" value="F:5'-3' DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000723">
        <property type="term" value="P:telomere maintenance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd18809">
        <property type="entry name" value="SF1_C_RecD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.10.10">
        <property type="entry name" value="Endonuclease/exonuclease/phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010285">
        <property type="entry name" value="DNA_helicase_pif1-like_DEAD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046700">
        <property type="entry name" value="DUF6570"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036691">
        <property type="entry name" value="Endo/exonu/phosph_ase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025476">
        <property type="entry name" value="Helitron_helicase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049163">
        <property type="entry name" value="Pif1-like_2B_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051055">
        <property type="entry name" value="PIF1_helicase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47642">
        <property type="entry name" value="ATP-DEPENDENT DNA HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47642:SF8">
        <property type="entry name" value="ATP-DEPENDENT DNA HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20209">
        <property type="entry name" value="DUF6570"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14214">
        <property type="entry name" value="Helitron_like_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05970">
        <property type="entry name" value="PIF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21530">
        <property type="entry name" value="Pif1_2B_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56219">
        <property type="entry name" value="DNase I-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0227">DNA damage</keyword>
    <keyword evidence="1" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="1" id="KW-0234">DNA repair</keyword>
    <keyword evidence="1 7" id="KW-0347">Helicase</keyword>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF6570" evidence="5">
        <location>
            <begin position="42"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="domain" description="Helitron helicase-like" evidence="4">
        <location>
            <begin position="297"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="domain" description="DNA helicase Pif1-like DEAD-box helicase" evidence="3">
        <location>
            <begin position="1042"/>
            <end position="1254"/>
        </location>
    </feature>
    <feature type="domain" description="DNA helicase Pif1-like 2B" evidence="6">
        <location>
            <begin position="1344"/>
            <end position="1390"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="160"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU363044"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF05970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF14214"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF20209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF21530"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OBZ82310.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="1796" mass="204354" checksum="B8A1F45E5016F3C5" modified="2016-11-30" version="1" fragment="single">SNRSLLMLCRNVKQAFIDSVFNIVFEDNVDKFCANCHKNIKKQKIPKISLSNGFELSPVPTEVKSLNRIEERLVSARHIFQSIYTVLGLRGQYKSKGGIVNAPVSVDKTVSCIPRTLNDSSCIEVKLTRRLIQNNNYMAGNVNVEKVWAAAMILKESEAYKKHNIRIRDSKEEYENIARELQEAYEIANIINDMAALSIENESSTEQIETSANDFNPGGQETLFSGELAPKVVEEINGGIRIAPAEGSAPLSLLLDKDVETLAFPSLFGGAILSPEHNGSPVTFSAIAKSLARHHDRRFAKRTDFLLFLDRKKQLLTLASHVNIMMRMSKTRTERPLNVRNLIQNDTLSASFKSDEAYKVLSRVRSTPAYWKKEKGDVMAMVRQLGIPTPFVTLSAAETKWPELLVILKKVVDDVVVTEDEANSLPNKEKSRLIQSDPITCARYSDKRMRILNSTWKPPHGPFGSHKILDYYYRIEFQHRGSPHAHMLLWLESAPVLDGGAYDNDSRQMRKDAICHFVDECMTCDPEVIEDDEEFKELVVSRQAHSHTRTCFKKSKKERKCRFNIPVFPMDETMVLDPLPEDEVAQYKESAKKIRNYLDNNFEGIRNSSLSFNQFLEVFGLSKIDYIKSIRATLKAPKVFLKREVRHSRINAFNKKILALHRANIDIQFVLDAYAYCSYIVEYINKNDLSTSDHLRLILEESVKNDEAPRKILQNLAAAYYNLSEVSAQEAAYNILQLKMCEASRATVFIATGPPEYRRRMLKSKDELMKMDGDSEDIYRKGSIEYYQARPRELEDTNLAQFVAFYDFVAKKGANRSNADDDYVDDDEVAEVVQERNNLLPLNDGVGYVRKRKHCKIIRYHLQALDQNPAVYYYSILMLYFPWRNEKDDLEDVDCAAKFEENRETVLSNRNEFSAIADETIEEFLAEAEQRASTENEDNDEEISTNEGQYNFEVNPFIESSRQLEPISDVNANTDNEDIHSQDFRLYLDAEDNRINAGEFDVEGHLAQVEERVEETSAALIDRYIRPDKLTPSNFYVLLSKLNNLQRDFLNHVINHIRHNTDGVDGPMPLKLFVTGGAGTGKSLLIKTLYQALVRFYDEDPHRDYNSPTILLTAPTGKAAFNIKGQTINSAFLLPINQSDINQLSPEISHSMTVALAELRVVIIDEISMISSRVFLWIDKRLRDIFDSEQPFGGRHVILFGDFLQLPPVKGQSIFAKPTDNLDLLTSTLRVQEIWHSFKVHRLTEIMRQRDDALFAKALNNMAIGAMTPSDVALFEGRLVASLPDDVQDNRDDCVVRLYHTNDSANHCNTTILFNIEDESYESACFDKVVGNSVDASTKRRYLDAIRSRNLPAHETMGLHELLMLKVGARYMVINNLDTSDGLINGTTGTLKKIEFGYYRPSQQSEPIQEAIRVWLLNDDADSGRKKRAASKDIVQNNPSISATWTPIDPVSLIVRGKPIYFIILEFQLIFFSLVNHRSNNALSLKRTQFPLTISEAATIHKSQGSTYKKVAIDLTGRSLKRSLMYVACSRATSASGLYLIGNKFKPTMPPAPNSSIALELERQGTVQLETTFKHLAKKDTDYEFQLIYHNVQSLKAHFNQITNDTAYLVSDFILLGETWTTSLQHFDLSGFEEVSRVDNQGTTLRANGSLCFVKKHLIEDRRILSKHATMIQDQNSHKMSISSFMVNETLIACIYCSPNFNKEMAMDEIKKLLLINASTRIIAGDFNSDFGADNDSIKRLFDDYGLVYNLNEKIKSTTRGSSFIDNIFTNIPEHESGRYISFTSYHDPLYIKFNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MZX2</accession>
    <name>A0A1C7MZX2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_11287</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001868">
        <property type="protein sequence ID" value="OBZ80664.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MZX2"/>
    <dbReference type="InParanoid" id="A0A1C7MZX2"/>
    <dbReference type="OrthoDB" id="441172at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="39"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="94"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="156"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="190"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="240"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="272"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="302"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="334"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="366"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ80664.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="470" mass="53875" checksum="B3CF37B44AF49083" modified="2016-11-30" version="1" fragment="single">RTSIYHLCSLLFIITFVISLSILVATVSSADSSSKNSPLLTQTALFIFVVSINLYLIARQRCYYMERRKLFGKTDEHINAVYETRFSNWDKSMFSNWIQIMILIIEFFQLMTFPLRDLINVTRTSQSQAHSSQLASLILNTGSLMPDMRTPTWYRYSLWTTFTTMMCSLFLGLLIHAINFRFPYKISTRWVRWCIPVATLLYIPVLTTFVSSAACQSLNVSSNDYSSTLRCNSATISRPLYFWLSLFGYIVAYVLLTVFLTSYERVPNKNEIAFKSISVAFIKNMGLLLAIVFLLVESTTNINRMRAILSIIILLTMICYNIKTQPCYVDKINFFRTISFACILWTSTLVAVLSDTNAAQSLGPVAVIYIIIGGWVFIVLCFFAIYFVYYIQPPDRSAIESSSTLHSHNGLSQAAYTTCSGDNHNQKKIDTQFQDSRFTRIFSKWFLLTNASKQDNDTQCSDCTDMHIRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-06-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N0N1</accession>
    <name>A0A1C7N0N1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_09317</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000823">
        <property type="protein sequence ID" value="OBZ82632.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N0N1"/>
    <dbReference type="InParanoid" id="A0A1C7N0N1"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ82632.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="78" mass="8759" checksum="FD3D06445EB986BD" modified="2016-11-30" version="1">MLRHVYDAEEKTHVIASDTVTLSNLIFMHFTNQEPSITFSILKDPAIFSITLLIDKINKSILPLSKSASLFGKQIGRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N1H6</accession>
    <name>A0A1C7N1H6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_10737</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001356">
        <property type="protein sequence ID" value="OBZ81214.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N1H6"/>
    <dbReference type="InParanoid" id="A0A1C7N1H6"/>
    <dbReference type="OrthoDB" id="2297559at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ81214.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="134" mass="15672" checksum="D4C5FAF1575C5753" modified="2016-11-30" version="1">MSRQEIRAFVSRFRFQDNSLASFNTLQKKQIERFRKFTQMKPDGFCCICLCVLYKDEQAYRTIEYAESSLKNCHEWKLVPLKNSQGNKYMVCKAHVNTNEGELSTYVYPGDLVPEAQALNNRERCVLSPLKLMT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N1X1</accession>
    <name>A0A1C7N1X1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_09278</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000814">
        <property type="protein sequence ID" value="OBZ82676.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N1X1"/>
    <dbReference type="STRING" id="101091.A0A1C7N1X1"/>
    <dbReference type="InParanoid" id="A0A1C7N1X1"/>
    <dbReference type="OrthoDB" id="2277247at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ82676.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="98" mass="11506" checksum="FB675824BDC749C3" modified="2016-11-30" version="1" fragment="single">MTVAERSLLVRWRLGWLPGGKPRPCTCGHSPLTKKHISLCLFFHLRLHVPTRVADPISYILNRLPKKRPTKDSSKRYWQFIWPSLINLLLQVDRIQHA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N269</accession>
    <name>A0A1C7N269_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">GATA-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">A0J61_09231</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000804">
        <property type="protein sequence ID" value="OBZ82719.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    <dbReference type="STRING" id="101091.A0A1C7N269"/>
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000122">
        <property type="term" value="P:negative regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
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        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="entry name" value="ZnF_GATA"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Nitrogen regulatory AreA, N-terminal"/>
        <property type="match status" value="1"/>
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    <dbReference type="Gene3D" id="3.30.50.10">
        <property type="entry name" value="Erythroid Transcription Factor GATA-1, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="AreA_GATA"/>
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    <dbReference type="InterPro" id="IPR039355">
        <property type="entry name" value="Transcription_factor_GATA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000679">
        <property type="entry name" value="Znf_GATA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013088">
        <property type="entry name" value="Znf_NHR/GATA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10071:SF281">
        <property type="entry name" value="BOX A-BINDING FACTOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10071">
        <property type="entry name" value="TRANSCRIPTION FACTOR GATA FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="GATA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08550">
        <property type="entry name" value="GATA_AreA"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="GATAZNFINGER"/>
    </dbReference>
    <dbReference type="SMART" id="SM00401">
        <property type="entry name" value="ZnF_GATA"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Glucocorticoid receptor-like (DNA-binding domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="GATA_ZN_FINGER_1"/>
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    </dbReference>
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        <property type="entry name" value="GATA_ZN_FINGER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
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    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0804">Transcription</keyword>
    <keyword evidence="5" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 8" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="GATA-type" evidence="10">
        <location>
            <begin position="538"/>
            <end position="591"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="47"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="139"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="289"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="428"/>
            <end position="526"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="589"/>
            <end position="608"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="622"/>
            <end position="771"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="70"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="146"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="298"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="428"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="450"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="510"/>
            <end position="520"/>
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    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="594"/>
            <end position="608"/>
        </location>
    </feature>
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        <location>
            <begin position="622"/>
            <end position="644"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="687"/>
            <end position="696"/>
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    </feature>
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        <location>
            <begin position="711"/>
            <end position="724"/>
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    </feature>
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        <location>
            <begin position="737"/>
            <end position="751"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="758"/>
            <end position="771"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
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    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00094"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50114"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="OBZ82719.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="771" mass="83117" checksum="95B6BA79C4C930FD" modified="2016-11-30" version="1">MQNSTTDSKGATKNLHLSDLRKKSTALANTAALSPKTPPAVTAALLSDSLFPPRRPKVDFNNPNSPQNNPDEDSEEEDEEGKKRKEDPLATQVWRLYTKAKDTLPNGSRLENLTWRMMAMTLNKKKKAEAEALEQQSLYNKHGEENADDQMEDRPNEDDDDIMEESTSATSPPPPDDTTTFLSSSAPPYMLDFMTLGHQHLQQMEHQQQQQQQQQEPMQVFHYPPLIQEPKKNVMVYGSTRASTPANLHVNNLSNSFRSNTTNGNTTNNNMFTNIYGVNSITIPADMDTSDDYRANDPTLSPLSSASSFRPSTSIESHHFNSYFSQSVPGYHHNFQQNFSTSPGGLFPQLGSNLPDSQQQQQFFAATPTENTPSPAAYSPLTTNNAGALSFEELLTMYYVNGDTSATSTTAAAAAAAAVAAAAASAVAGTPPSTTTSNSMLIHNLPPNPNFSLPQQQTQDGLRTPNGQSSPIQPSPLSPSYNSTNSLSRLAITNEDQLPPNPSIVGSPIAQKNSTCLPSQQDKKSEEARITVKKEMGTNANTKCTNCETTTTPLWRRNPEGQPLCNACGLFLKLHGVVRPLSLKTDVIKKRNRSGNSNAAGNPQKVSGISPITVNTLAASSSSSATSSSSSSSHSSSSVSVAISNPPTSMTGKKPNPFLQASPVSTSNHPPIYKRQSIGGTGMVNIAPTTANTNANSTIQQSGGSNGRPMTFSTSRWGTQQSITKRQRRHSVDENKPQQPSSQPPQTQSQQGVFRVGSLNNTSAFPSSPSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N2I2</accession>
    <name>A0A1C7N2I2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Ribosomal lysine N-methyltransferase 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">RKM3</name>
        <name evidence="3" type="ORF">A0J61_08639</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000684">
        <property type="protein sequence ID" value="OBZ83313.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N2I2"/>
    <dbReference type="STRING" id="101091.A0A1C7N2I2"/>
    <dbReference type="InParanoid" id="A0A1C7N2I2"/>
    <dbReference type="OrthoDB" id="441812at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016279">
        <property type="term" value="F:protein-lysine N-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd10527">
        <property type="entry name" value="SET_LSMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1410.10">
        <property type="entry name" value="set domain protein methyltransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011383">
        <property type="entry name" value="N-lys_methylase_SETD6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001214">
        <property type="entry name" value="SET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046341">
        <property type="entry name" value="SET_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050600">
        <property type="entry name" value="SETD3_SETD6_MTase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13271:SF34">
        <property type="entry name" value="N-LYSINE METHYLTRANSFERASE SETD6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13271">
        <property type="entry name" value="UNCHARACTERIZED PUTATIVE METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF011771">
        <property type="entry name" value="RMS1_SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82199">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50280">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="SET" evidence="2">
        <location>
            <begin position="44"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="178"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="372"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="542"/>
            <end position="568"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="381"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="553"/>
            <end position="568"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ83313.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="568" mass="65433" checksum="1A2ED108D43F1F4D" modified="2016-11-30" version="1" fragment="single">IANILDEASLEGGCPLALAVLYEIAQKEQSPWYGYLQALPDQGEDLPIFWDESEKALFNGTEMESAVRNDLNDLQEDYNELIVPLLEEHPYVFKRGETPEQDPYSFERFLKISTLISSRAFEVDAYHENALVPFADIFNHRGENEHVHFETEFEVCDACGALEYCEHQYFHYMYNSDAEGEEEENEEWEDEEDASDMEGDEDGSDMEEEEEPLDTDLPDLEELENAGVNFYENSDEEEEEEKKDTCDMVVDSDIKEGEEVFNTYGEHPNIALLSKYGFCYDNNTNDYISVDENTIVDCVIAVTAENLKTKKPKATEEQLEKLAIEKTGPRWEFFLENEHILCPSADSEEDQQDDFDDEDGCQDGCCGDEHGHDHSEHEDHEDHEEEHEHDEDGGCCSGEDEKAGKSKPYFVNYEGLFEDKLMCLLHVMFVSEAKFAKFTEDVENALEYFEELAESQGENKTKAMIETKLQIYHVCRALVEIRRMDYLEDGEWKTVEQELEERNKVADNKRKYYALTCRISEKKIIEKAIAYYADLIKEYSSATPVASNASSSKSKKKTASKKIKKMKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N3K0</accession>
    <name>A0A1C7N3K0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Nucleolar complex protein 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">NOC2_0</name>
        <name evidence="5" type="ORF">A0J61_10047</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the NOC2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001012">
        <property type="protein sequence ID" value="OBZ81904.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N3K0"/>
    <dbReference type="STRING" id="101091.A0A1C7N3K0"/>
    <dbReference type="InParanoid" id="A0A1C7N3K0"/>
    <dbReference type="OrthoDB" id="10266662at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030690">
        <property type="term" value="C:Noc1p-Noc2p complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030691">
        <property type="term" value="C:Noc2p-Noc3p complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005654">
        <property type="term" value="C:nucleoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042273">
        <property type="term" value="P:ribosomal large subunit biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005343">
        <property type="entry name" value="Noc2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12687">
        <property type="entry name" value="NUCLEOLAR COMPLEX 2 AND RAD4-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12687:SF4">
        <property type="entry name" value="NUCLEOLAR COMPLEX PROTEIN 2 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03715">
        <property type="entry name" value="Noc2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="46"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="140"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="49"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="66"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="142"/>
            <end position="166"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005907"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OBZ81904.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="650" mass="75443" checksum="757D57455B4BEF2B" modified="2016-11-30" version="1">MLFEPRFYEIHTCLLRHRSNMGKEKKSTIKFQKNKLKGVISRRKEVNKFKKQIAKRQARRTGSKNPHKETEESLERAEDKQETTTEETPKLNTEDYFCNFVIDDEEPLDLSDDEEDDLNALDGFEALATKDELVVDEGLDHDMEDDDEENEEEEEEEPFDEEDEDMSNAETVTMDMINEWSTQANTKSPLAWKKLLLAFRSIVRSGEDHQFCYRVDNSKVYTKVVRNTLLVAYPILSQHIYFLKKEKYPGKTKNWPKLEKVVRLFLNNCVRFLRELTEDDIIQYVLEKLEPCTLYFGCFPKLSREYLRVLLDRWSDTALSEETRNQCFKALHQLGTTALDANRKNYMPNVLKGVYLIFANRATKINQVSLPVLQQMIEEAADLYAVDHQLSYEHASVYIRQLADHLKGAKKKNTAESFKKIYTWQYINCLDFWASAVSATCDPSVGEHSPMQSIVHPLVEVTLHTIRLNPTPSFLPLRIHLVRTLTGLMDGTGYYIPLAPYLFEILSSDALKGQQPSVDGLPEFEWQLHLKTPKSYVQTKEYQTAVYNVMYDCLVDFYGCVGLSIAFPELAIPAIVKLKEYQSKMKGTRFVKSLRTLIEKMETHKNYIEQKRAPIEYTANNLQEANAFLRTTDFQTTPLGQFLKKRSQSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N3V2</accession>
    <name>A0A1C7N3V2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Elongation factor Tu</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">TUF1</name>
        <name evidence="11" type="ORF">A0J61_08143</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000601">
        <property type="protein sequence ID" value="OBZ83803.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N3V2"/>
    <dbReference type="FunCoup" id="A0A1C7N3V2">
        <property type="interactions" value="586"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N3V2"/>
    <dbReference type="InParanoid" id="A0A1C7N3V2"/>
    <dbReference type="OrthoDB" id="2067at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070125">
        <property type="term" value="P:mitochondrial translational elongation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01884">
        <property type="entry name" value="EF_Tu"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03697">
        <property type="entry name" value="EFTU_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03707">
        <property type="entry name" value="EFTU_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.30.10:FF:000001">
        <property type="entry name" value="Elongation factor Tu"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000003">
        <property type="entry name" value="Elongation factor Tu"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.10">
        <property type="entry name" value="Translation factors"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00118_B">
        <property type="entry name" value="EF_Tu_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041709">
        <property type="entry name" value="EF-Tu_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050055">
        <property type="entry name" value="EF-Tu_GTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004161">
        <property type="entry name" value="EFTu-like_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033720">
        <property type="entry name" value="EFTU_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031157">
        <property type="entry name" value="G_TR_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000795">
        <property type="entry name" value="T_Tr_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009001">
        <property type="entry name" value="Transl_elong_EF1A/Init_IF2_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004541">
        <property type="entry name" value="Transl_elong_EFTu/EF1A_bac/org"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004160">
        <property type="entry name" value="Transl_elong_EFTu/EF1A_C"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00485">
        <property type="entry name" value="EF-Tu"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF000766">
        <property type="entry name" value="PRK00049.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF009372">
        <property type="entry name" value="PRK12735.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF009373">
        <property type="entry name" value="PRK12736.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43721:SF36">
        <property type="entry name" value="ELONGATION FACTOR TU, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43721">
        <property type="entry name" value="ELONGATION FACTOR TU-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00009">
        <property type="entry name" value="GTP_EFTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03144">
        <property type="entry name" value="GTP_EFTU_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03143">
        <property type="entry name" value="GTP_EFTU_D3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00315">
        <property type="entry name" value="ELONGATNFCT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50465">
        <property type="entry name" value="EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="Translation proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00301">
        <property type="entry name" value="G_TR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51722">
        <property type="entry name" value="G_TR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 9 11" id="KW-0251">Elongation factor</keyword>
    <keyword evidence="8 9" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="7" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="3 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="Tr-type G" evidence="10">
        <location>
            <begin position="81"/>
            <end position="277"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022768"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU000325"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="OBZ83803.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="472" mass="51473" checksum="2B389B71F224E821" modified="2016-11-30" version="1">MFALKTAANKVALPATRVASRRCITSSAARSAFSSTRLALNAGNKMASNILREAYVANPSRMMFFGRRTMATDSGKFSRGKPHVNIGTIGHVDHGKTTLTAAITKTLAIEGGAQFMDYNQIDKAPEEKARGITISTAHVEYETPNRHYAHVDCPGHADYIKNMITGAAQMDGAIIVVSATDGQMPQTREHLLLARQVGVQNLVVFINKVDQVDDPEMLELVEMEMRDLLSEYGFDGEATPIVKGSALAALEGRDPEIGEKAIKELMANVDAHIPTPIRDLDKPFLMPIEDVFSISGRGTVATGRVERGVCLKGQEVEIVGMGAPTKTTLTGIEMFRKELDRGEAGDNMGALLRGIKREQIRRGQVLCAPGSVKSHKKFLAQIYILTKDEGGRHTPFVNNYRPQMFVRTTDVTVSLTHPDGTEDPDDKLVMPGDNVEMQCELVHDVALEDGQRFTIREGGKTVGTGVVTKIIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N429</accession>
    <name>A0A1C7N429_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Spindle pole body component</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">TUBGCP4</name>
        <name evidence="10" type="ORF">A0J61_08120</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Cytoplasm</location>
            <location evidence="1 6">Cytoskeleton</location>
            <location evidence="1 6">Microtubule organizing center</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the TUBGCP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000597">
        <property type="protein sequence ID" value="OBZ83830.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N429"/>
    <dbReference type="STRING" id="101091.A0A1C7N429"/>
    <dbReference type="InParanoid" id="A0A1C7N429"/>
    <dbReference type="OrthoDB" id="1608002at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000930">
        <property type="term" value="C:gamma-tubulin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000922">
        <property type="term" value="C:spindle pole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005816">
        <property type="term" value="C:spindle pole body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043015">
        <property type="term" value="F:gamma-tubulin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051011">
        <property type="term" value="F:microtubule minus-end binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031122">
        <property type="term" value="P:cytoplasmic microtubule organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051321">
        <property type="term" value="P:meiotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007020">
        <property type="term" value="P:microtubule nucleation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000278">
        <property type="term" value="P:mitotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051225">
        <property type="term" value="P:spindle assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1900">
        <property type="entry name" value="Gamma-tubulin complex, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007259">
        <property type="entry name" value="GCP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040457">
        <property type="entry name" value="GCP_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042241">
        <property type="entry name" value="GCP_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041470">
        <property type="entry name" value="GCP_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19302">
        <property type="entry name" value="GAMMA TUBULIN COMPLEX PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19302:SF27">
        <property type="entry name" value="GAMMA-TUBULIN COMPLEX COMPONENT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04130">
        <property type="entry name" value="GCP_C_terminal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17681">
        <property type="entry name" value="GCP_N_terminal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3 6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 6" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="4 6" id="KW-0493">Microtubule</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Gamma tubulin complex component protein N-terminal" evidence="9">
        <location>
            <begin position="2"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="domain" description="Gamma tubulin complex component C-terminal" evidence="8">
        <location>
            <begin position="311"/>
            <end position="637"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="76"/>
            <end position="103"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010337"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU363050"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF04130"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF17681"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OBZ83830.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="640" mass="74622" checksum="093C7F95B797A134" modified="2016-11-30" version="1">MLHELLFVLLGYPGDVFIAYPSHKPTTFAIPSSFPLLHPSERQCLDRLGQLGWTYLQIHQFNRRTQHKGAYVQACVQCLENTLNDYRETILQMETRILNKQDDFGQGIVPLSLITAQLADWELLLPALVGLIDRLEQHPEQYHGCKMFQLLMDQAKTGMAPLRTVLDKMIHQLHAVLYRQLTTWIIYGQSVDPDHEFFIVPSNEEKGRWQLYVIDADFIPPHLTHALAESILFVGKAIATVHAMDRLSFQQNLKIPMNMRQHHLQLLSTLYQPHTSPWIQYPQQLTQVVHQIRRSTADWLFSQVLVGDHGLHAYLKTFRHVFLLDYGDFATHFIDECLLWRRRSIDTTEATGRTTLLFHTQEINALLIKASVGTEAEDQLDGFHLLLEKTEEYPFADLLLKHLPMVMTFELTWPIDLFISPSDLKQYSHLWSFLISLKATQMALSNLWKLLREGMGQDEQAVWQLRSQMLFWVDTFWSHIQIYVIDAHYQQLIEATSSDQQRAWASNKHDFETIQAAHTQFLTHTMRGCLLWSHQCVKTLHGIIKTCLDFCQFMERMAEEGEWKPSHQKKRKTASEIVQQWTQTDERPWIDSVKQLQETFHHQTQHFFALASNQQPEAKSSGQIDALLMQLDFNGWFSKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N468</accession>
    <name>A0A1C7N468_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="3">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="primary">kin1_1</name>
        <name evidence="15" type="ORF">A0J61_08028</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. NIM1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="3"/>
    <dbReference type="EMBL" id="LUGH01000583">
        <property type="protein sequence ID" value="OBZ83925.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N468"/>
    <dbReference type="STRING" id="101091.A0A1C7N468"/>
    <dbReference type="InParanoid" id="A0A1C7N468"/>
    <dbReference type="OrthoDB" id="193931at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035556">
        <property type="term" value="P:intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000226">
        <property type="term" value="P:microtubule cytoskeleton organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:001222">
        <property type="entry name" value="Serine/threonine-protein kinase ppk25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24346:SF82">
        <property type="entry name" value="KP78A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24346">
        <property type="entry name" value="MAP/MICROTUBULE AFFINITY-REGULATING KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 12" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8 15" id="KW-0418">Kinase</keyword>
    <keyword evidence="7 12" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="14">
        <location>
            <begin position="28"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="404"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="515"/>
            <end position="542"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="410"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="59"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010791"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="OBZ83925.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="672" mass="77249" checksum="0F21B5A8E0761758" modified="2016-11-30" version="1">MTVNSPTPHQLEASPKPRYHTQHIGNYVIHKKTLGSGSMGTVKLAESLSPKDHQLYAVKIMPKINPNQIEHTKTNDPKDTPREREQRTIREMAIMHLLRHPNICQLKEWVVHGDQYYMFLEYIQGGQLLDYIISHGKLREKLARKFTRQIVSALDYCHKNSIVHRDLKIENILITAQQEIKIIDFGLSNIYSPSRLLDTFCGSLYFAAPELLQARHYTGPEVDVWSLGIVLYVLVCGRVPFDDTSLPALHQKIKSGLVDYPDHLSRDCVDLLSKILVVDPSKRATLSQVIHHSWINKGYDEPIFNYLPLRQPLKQIDPEVVKGMQGFGLGEPEEIEAKLNEIIHSPDYANLCETPPPTVSQENVRWRLSMRRPSPQRMESTLSDPLISIYSLVKERRERDAKDRLLESEGYQSPVQLGRSASTSLAKSNTAHQGNLMRRKTERVPPSHTRRVFSDTESDWASPVSHPPQPTNLLQRSKSAAKRLLNKSLEDVDFVPTSLSSTELSLRQKTMNLFRSTSLSDRRRTKSPSQGGRFIEEGISTPDIPKMSAHPKSLFNFNHRHLFKLSTHDMLKYTQYVLLKLGIRYRPSHEPFTLRCELTDWHRFQPFEETDQELVEIHTPIPFTLMIYQARWAGGRLGVKLIEAEEDQEGVYRRIYHTILNQLGYTIKAQST</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N4E8</accession>
    <name>A0A1C7N4E8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_07982</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000576">
        <property type="protein sequence ID" value="OBZ83970.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N4E8"/>
    <dbReference type="InParanoid" id="A0A1C7N4E8"/>
    <dbReference type="OrthoDB" id="2247269at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ83970.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="181" mass="21641" checksum="3D53EFF0C6B2BE83" modified="2016-11-30" version="1">MVFLCDKFGVDGYLDLMENKIASRFKQYLKDATIKLQLSLQPMTTIQEREMLMKIAECKNRMDVDDLLAIFYARRNMDPMCRYIRLAFVTAAELWSSRLLLKVDHNESWFRPHSLLSCFRQCIYSYSNITKEFEDVDNQRVDFILRNINDDNDYLSAEEKPNLKCAKRYYVKEMDWPILEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N4R2</accession>
    <name>A0A1C7N4R2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Vacuolar transporter chaperone 4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">VTC4_0</name>
        <name evidence="8" type="ORF">A0J61_08303</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000627">
        <property type="protein sequence ID" value="OBZ83646.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N4R2"/>
    <dbReference type="STRING" id="101091.A0A1C7N4R2"/>
    <dbReference type="InParanoid" id="A0A1C7N4R2"/>
    <dbReference type="OrthoDB" id="6493944at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006799">
        <property type="term" value="P:polyphosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.100.30">
        <property type="entry name" value="VTC, catalytic tunnel domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051572">
        <property type="entry name" value="VTC_Complex_Subunit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018966">
        <property type="entry name" value="VTC_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042267">
        <property type="entry name" value="VTC_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46140">
        <property type="entry name" value="VACUOLAR TRANSPORTER CHAPERONE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46140:SF1">
        <property type="entry name" value="VACUOLAR TRANSPORTER CHAPERONE COMPLEX SUBUNIT 4-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09359">
        <property type="entry name" value="VTC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="709"/>
            <end position="731"/>
        </location>
    </feature>
    <feature type="domain" description="VTC" evidence="7">
        <location>
            <begin position="200"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="517"/>
            <end position="537"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="554"/>
            <end position="574"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="519"/>
            <end position="532"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="560"/>
            <end position="569"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF09359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OBZ83646.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="734" mass="85380" checksum="E5A5BDD9D864A7C4" modified="2016-11-30" version="1">MNQTNFPIYWMPLPESQDLLSLIAQPISCEEDWIENLYLPWQIFYIDYIDLKTTVMDNLWAQRLQAEWDKLHQFYLSKKEEIHKAFQQVNNGSYDSFETISTDIYHLHQFLKLNYRGLLHLFMLHDRLYEKSTYDARSKSPYFKNYFWDDASRAVHELAINTNQLFINNRYSPLDAYLKNVVQTSSSSNQTDAKNCRTVAKKYWVHPSHLLELTLLLSKEAFIVENPIACAGAKTQIKHPLYQQSGRKPIVSTVYLDTDLFEDYHNNLELISTIQSSQAKTTTATLSRSRAFASDKVEVPKVYALEHKIHRVVQDAHEYCIDKRIQVEQKNLNDWIQSAYSINEVLDDPLMEYSKEKQIIEGSSKNEMKQDYIQWEEEMRKTSRKPVLHVTQNRIVYASQGQSVFITIDTDITMMHMSQPEVSSSSSALPQATSFPYCVVQVHGELEEDSKLCHTLMRLVENRLLYATDHFSIYLHGVATLFADQVDRLPYWFGLPSELFEPNNNNWLDRHFSEIPNASSTRPTSSRRSSSTLYHDRASSSATASTIITCFENDSESDDSASSSSSSSSKQQHKILPMPTFQLKHDMSLLRPTWYQKGNFRRSFDSVCSFDHPTSSRSDPANCRDCMIYVSHGNHDEQDEWADQQSRNSMHYSYQESRILSSFFYKIFWPSRLRSLEKEPLLGANRKRCYLSFYKTQDDLVPNPITKSMHALTTFLILIVLCLPLSVYFILKVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N4X7</accession>
    <name>A0A1C7N4X7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_08258</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000620">
        <property type="protein sequence ID" value="OBZ83689.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N4X7"/>
    <dbReference type="STRING" id="101091.A0A1C7N4X7"/>
    <dbReference type="InParanoid" id="A0A1C7N4X7"/>
    <dbReference type="OrthoDB" id="2363016at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ83689.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="92" mass="10816" checksum="8D7F93C17278079C" modified="2016-11-30" version="1">MKAYRGWIEPYLTETNWAAFRRNIMVGERIMQLTKVVGQGVLLMTKELSGSKLHLTFTNNEWDEFIQGKRRREEQLFDHCGLKNLSNVIQTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N540</accession>
    <name>A0A1C7N540_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Putative MFS-type transporter C16A3.17c</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">A0J61_07718</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000538">
        <property type="protein sequence ID" value="OBZ84232.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N540"/>
    <dbReference type="FunCoup" id="A0A1C7N540">
        <property type="interactions" value="36"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N540"/>
    <dbReference type="InParanoid" id="A0A1C7N540"/>
    <dbReference type="OrthoDB" id="10021397at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd17502">
        <property type="entry name" value="MFS_Azr1_MDR_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1720.10:FF:000013">
        <property type="entry name" value="Related to multidrug resistance proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1720.10">
        <property type="entry name" value="Multidrug resistance protein D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501:SF102">
        <property type="entry name" value="DRUG TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G08530)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01036">
        <property type="entry name" value="TCRTETB"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="62"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="98"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="129"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="154"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="187"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="219"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="253"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="284"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="323"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="364"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="389"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="420"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="454"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="523"/>
            <end position="542"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="9">
        <location>
            <begin position="64"/>
            <end position="547"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="547"/>
            <end position="585"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="7"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="554"/>
            <end position="568"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OBZ84232.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="585" mass="64073" checksum="7F263FC5062C30A3" modified="2016-11-30" version="1">MEKTEISDQTTPTNEQSDTSISTLDQHDAQSGKEATTSVEPGKEDNVDALEAVGRKAKIGRILTFIGLQIALFLGALDNTIVATALPRIGSDFNQMSIVAWVATAYILTFDAFQPLFAKFSDIFGRKWILLFGIAVFLFGSVLCGAAQSMIMLIIARAIAGIGAAGIFSMVFVIFSELVPLEKRGSYQGIINSVFALSSVFGPLIGGSLTDYVSWRWNFYINLPIGAAAMAVLFVFLKLPTPKGKLSEKLKRVDYAGTFIVLAFATLFLLALNFGGQTFPWKSAAVIVPLVLSIGLIGLLVLVEKKFAKEPLMPPRLFKNRSVVSVLITNWFFGMTFFSAVYYLPVYFQVVRNDSAMWSGIRLIPMQMVLCVISTCSGLFISKTGVYRPLIVSGMFFLTLWIGLTSLYDRDTPWSRIYGITIIGSLGLGSLFSSTIIALQAAVPPRDIAVVTGLGNFSRILGGALGVAVSSAVLNSQLNQELYKHIPEELALAVIQSSEFVNHGLPEEYKEATLEVYVHALRLIWWVLIPMAGIGLTASLFVKHHSTRSHQKHRDAEKVKEEAKKEPSNNEEVVTVNIPEETQAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N5C6</accession>
    <name>A0A1C7N5C6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">FAS1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_08080</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000591">
        <property type="protein sequence ID" value="OBZ83869.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N5C6"/>
    <dbReference type="STRING" id="101091.A0A1C7N5C6"/>
    <dbReference type="InParanoid" id="A0A1C7N5C6"/>
    <dbReference type="OrthoDB" id="286301at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.180.10">
        <property type="entry name" value="FAS1 domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050904">
        <property type="entry name" value="Adhesion/Biosynth-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036378">
        <property type="entry name" value="FAS1_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000782">
        <property type="entry name" value="FAS1_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10900:SF77">
        <property type="entry name" value="FI19380P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10900">
        <property type="entry name" value="PERIOSTIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02469">
        <property type="entry name" value="Fasciclin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00554">
        <property type="entry name" value="FAS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82153">
        <property type="entry name" value="FAS1 domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50213">
        <property type="entry name" value="FAS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAS1" evidence="2">
        <location>
            <begin position="105"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="241"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="241"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="264"/>
            <end position="273"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50213"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ83869.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="297" mass="32713" checksum="883C10F82F6449E4" modified="2016-11-30" version="1">MESYLNYSISIGQLNFSQPDDTMEYFKSFVLNGTYQSQTFKNSRRSYPTLTDNRLSIGPYLTPDYKLSNNSLVVYSGITKASIHISDIYCKNGIVQVVSQFLEPAQSPLDTISIIPETQYMEELLKALNVSGVVSNTNRTILVPTNQAWINANGSSIPFGTLVHDLSYLSLEGIYFSDQLSTGDRHALPTSYKDSDIVIQLKKNKLLVNNIAEIVEKDIITTSGVMHLIDAVVLADSAIDENQNGTDSSNSSDVIANDHDSGDSHGNTSLNRSEASCITHRSPLYALINPEENSLDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N6F1</accession>
    <name>A0A1C7N6F1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Pre-mRNA-splicing factor</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">AQR</name>
        <name evidence="7" type="ORF">A0J61_09044</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Involved in mRNA splicing where it associates with cdc5 and the other cwf proteins as part of the spliceosome.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Belongs to the 40S cdc5-associated complex (or cwf complex), a spliceosome sub-complex reminiscent of a late-stage spliceosome.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the CWF11 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000761">
        <property type="protein sequence ID" value="OBZ82904.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="FunCoup" id="A0A1C7N6F1">
        <property type="interactions" value="843"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N6F1"/>
    <dbReference type="InParanoid" id="A0A1C7N6F1"/>
    <dbReference type="OrthoDB" id="1879at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071013">
        <property type="term" value="C:catalytic step 2 spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005684">
        <property type="term" value="C:U2-type spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045292">
        <property type="term" value="P:mRNA cis splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd17935">
        <property type="entry name" value="EEXXQc_AQR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18808">
        <property type="entry name" value="SF1_C_Upf1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:002863">
        <property type="entry name" value="Pre-mRNA-splicing factor cwf11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048966">
        <property type="entry name" value="Aquarius_b-barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048967">
        <property type="entry name" value="Aquarius_insert"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032174">
        <property type="entry name" value="Aquarius_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026300">
        <property type="entry name" value="CWF11_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045055">
        <property type="entry name" value="DNA2/NAM7-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041679">
        <property type="entry name" value="DNA2/NAM7-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041677">
        <property type="entry name" value="DNA2/NAM7_AAA_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047187">
        <property type="entry name" value="SF1_C_Upf1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10887">
        <property type="entry name" value="DNA2/NAM7 HELICASE FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10887:SF5">
        <property type="entry name" value="RNA HELICASE AQUARIUS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13086">
        <property type="entry name" value="AAA_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13087">
        <property type="entry name" value="AAA_12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16399">
        <property type="entry name" value="Aquarius_N_1st"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21143">
        <property type="entry name" value="Aquarius_N_2nd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21144">
        <property type="entry name" value="Aquarius_N_3rd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF038901">
        <property type="entry name" value="AQR_cwf11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="1" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RNA helicase aquarius N-terminal" evidence="4">
        <location>
            <begin position="40"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="domain" description="RNA helicase aquarius beta-barrel" evidence="5">
        <location>
            <begin position="498"/>
            <end position="667"/>
        </location>
    </feature>
    <feature type="domain" description="RNA helicase aquarius insertion" evidence="6">
        <location>
            <begin position="715"/>
            <end position="802"/>
        </location>
    </feature>
    <feature type="domain" description="DNA2/NAM7 helicase helicase" evidence="2">
        <location>
            <begin position="814"/>
            <end position="1111"/>
        </location>
    </feature>
    <feature type="domain" description="DNA2/NAM7 helicase-like C-terminal" evidence="3">
        <location>
            <begin position="1120"/>
            <end position="1310"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRNR" id="PIRNR038901"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13087"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF16399"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF21143"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF21144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OBZ82904.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="1397" mass="162707" checksum="BC9447271DF7621A" modified="2016-11-30" version="1">MFHKTTLPLHAVPSEVSSLKQHGSLTLADIQSDNTSKLAQKHFDAAFDPTLIEDIYTNELKASQFSSQKLMLLEFNQYLEKYLWPHYTDKASVNHVISICLIVNEKARQHNSVWDAFREKEKFSHLFRQVIEMLNDTSLDLFLTRQLLTFMIICFQSFENDLVRTECLKLVTIGIWTHLAYESTREQLFDSYPNLLKLWNSYQKKWKAADEATQQQWVFERNWLSQLLHRFIDLIYQIPGDQEVEVDQELIYVCERFLEFFVDLEAQLPTRRFFNTLLDDHQIVVLSQLAPFHQRQQKDVELLKKLLDNLAFYAKFEINDQTGVALSDLDITQAHCQQLLSLQRTVFRLFKEEIRELPLANLGSIETRQDLLWHLEPLSNDVLIRLCDALGIRSSPIVDKVDIKQLLIHVLINRYQKRESQIQKINSQPLYPDEHTLFDDQLIQSQFYTGDRPLALPKLNLQFLTLHDYLLRNFILYRLESAYEIRQDLEDVVKRLAPRLTYPDRKTEFAGWARMAVSIDEMTIMDVGQPNLGEEKPSFVHADISFQVARFTNTIREEWDALRKHDVLFLLSIEATETSNEKMKDDEDFRQHYGIKWIRGCEVVDILGHDGKPMDENYRPTAQDKALKWKGANRKIRVALDTCQYKMDLDNKQSGDMYQSFNILVRRKPQENNFKAVLDTIRDLMQTDLVVPDWLQKVFLGYGDPSSAHYVNMPNRERTINFRDTFLDWQHLKESFLNRELVETVEGDNNDQLEPPYVVTLLDEAAEKPVKKSKKQEQKKKKETLEISSYKVPHMGPYPQNAPKKNHIRFTPVQIESIYSGLNHGLTMVVGPPGTGKTDVAVQTMVNLYQNHPEQHTLIVTHSNQALNQIFEKMIELDIDPRHLVRLGHGEEELRSELDFSKHGRVASALERRLALLAQVDRLSQSLAILGEHGSTCETATYFYHVHVLPRWEAFLAQIDTDKSVEQIRDLFPFAQYFANVPQPIFTDTMTPEEAIESSQGCFRHLKAIFAELEDIRPFELLRSGSDRANYLLTKEAKIIAMTCTHAALKRRELVDLNFKYDNIVVEEAAQIFEIETFIPLVLQTLDEGKSRLKRVMLIGDHHQLPPVVKNSAFQKYGRMEQSMFARFVRLGVPTLQLDQQGRARPSIAKLYNWRYHPLLDDLERVRVDEYTRANAGLKYDYQLIHVDAYQGESEPVPFFYQNLGEAEYVVAMYQYMRLIGYPAEKISILTTYNGQKALINDVLEKRCGWNPYFGKPATVNTVDKYQGQQNDYVLLSLVRTKTVGHIRDIRRLVVAMSRARLGLYVFCNKTLFENCYELESTFKQLTARSSQLQILPSEKYPTERSLDAEVTNSVAVADVEEMGKLVYKLSQEQLEWMRQQEAERLAQEKEAMEEDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N6H9</accession>
    <name>A0A1C7N6H9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_07716</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000537">
        <property type="protein sequence ID" value="OBZ84236.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N6H9"/>
    <dbReference type="InParanoid" id="A0A1C7N6H9"/>
    <dbReference type="OrthoDB" id="2284111at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="81"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="117"/>
            <end position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ84236.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="181" mass="20803" checksum="B8E6FDEC88A844C8" modified="2016-11-30" version="1">MWSSKRTATGLTNSRSAPCTIFSTTALSPRQIANKAYTLGCKKLDRDDKRSKQKYHVRERLLLCNTIAKAEEVLNTRTRRTNRRVMAAEDEDSNEEFSQKPMSHTSEHHSPLRSSSDDEEEEEEEEEEEQQTIPIQPIIQQHMHINHNITNPINDSLLHRDCRTTMSKPNTSSNNAITTII</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N708</accession>
    <name>A0A1C7N708_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">A0J61_07511</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000510">
        <property type="protein sequence ID" value="OBZ84436.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N708"/>
    <dbReference type="InParanoid" id="A0A1C7N708"/>
    <dbReference type="OrthoDB" id="6365676at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000072">
        <property type="entry name" value="zinc finger protein 143 isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="7">
        <location>
            <begin position="215"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="57"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="142"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="59"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="148"/>
            <end position="158"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OBZ84436.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="264" mass="30404" checksum="513E65125A3A3AC9" modified="2016-11-30" version="1">MTTNYPQEETQRYVNPNSLSQQESYDYHHFLKRQDPYQRRFSYTSMLSDADPCYLPAVSNSSPSSNHSEDYPSQQHTPPPTSSNPSGMQSFMDYVDLQSKPPVNQQSIYHPTMPYYEAHSKNLLNYDEHYSHRNAMIQMSSQQQQQQNGFSSMCSTPTPHHLSMKQERPMTPVSPPLKDENAAQQSSTIPDKLKRVPRSRGRRVSNVPGCGTRMFTCKADGCGKVFKRSEHLKRHIRSIHTLEKRKLELFYASDLVTHHASFSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N710</accession>
    <name>A0A1C7N710_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_07038</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000456">
        <property type="protein sequence ID" value="OBZ84913.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N710"/>
    <dbReference type="InParanoid" id="A0A1C7N710"/>
    <dbReference type="OrthoDB" id="2289008at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="37"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="53"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ84913.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="174" mass="20570" checksum="70F658BF95B5C562" modified="2016-11-30" version="1">MNRLGFGEFHRKHFGPEQQQYWQAMLFQQAPHLYDEPYYPNHDQQTWNKEEDQPVTEEPTEDYPDQTLSREAIEIFQFSEAYRKERERERLELEEEETKGMEGWQYGESNVLVSGGIEAPATNLVLIRPRPNEESEIRMKEDMLNSAYLASCSNLNSTDRDDNIVLWPVVPLKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N754</accession>
    <name>A0A1C7N754_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Zinc finger A20 and AN1 domain-containing stress-associated protein 7</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">SAP7_1</name>
        <name evidence="8" type="ORF">A0J61_07028</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000454">
        <property type="protein sequence ID" value="OBZ84922.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N754"/>
    <dbReference type="STRING" id="101091.A0A1C7N754"/>
    <dbReference type="InParanoid" id="A0A1C7N754"/>
    <dbReference type="OrthoDB" id="428577at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.4770">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.1110.10">
        <property type="entry name" value="AN1-like Zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035896">
        <property type="entry name" value="AN1-like_Znf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050652">
        <property type="entry name" value="AN1_A20_ZnFinger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002653">
        <property type="entry name" value="Znf_A20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000058">
        <property type="entry name" value="Znf_AN1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10634">
        <property type="entry name" value="AN1-TYPE ZINC FINGER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10634:SF67">
        <property type="entry name" value="AN1-TYPE ZINC FINGER PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01754">
        <property type="entry name" value="zf-A20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01428">
        <property type="entry name" value="zf-AN1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00259">
        <property type="entry name" value="ZnF_A20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00154">
        <property type="entry name" value="ZnF_AN1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF118310">
        <property type="entry name" value="AN1-like Zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57716">
        <property type="entry name" value="Glucocorticoid receptor-like (DNA-binding domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51036">
        <property type="entry name" value="ZF_A20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51039">
        <property type="entry name" value="ZF_AN1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="A20-type" evidence="6">
        <location>
            <begin position="10"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="domain" description="AN1-type" evidence="7">
        <location>
            <begin position="106"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="39"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="82"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="96"/>
            <end position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00449"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51036"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51039"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OBZ84922.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="182" mass="20316" checksum="9772C88AE1A4CE00" modified="2016-11-30" version="1">MENDNNNKSEKAPSLCSAGCGFFGSEAFDNMCSQCFKAQNKTSSEPTKPMVKSPSIDDTSIVTAIEKSRKHLRSPSPIEQRTSSAPVSSTASPPTLQDTPNEKPIQQNKGRCFKCRLKVPLAKQATNKCRCGYVFCDSHRYPDRHDCDVDYAKMDREILAKNNPKLHERPKGGRSFQRIDSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N7T7</accession>
    <name>A0A1C7N7T7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Calmodulin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">CALM_0</name>
        <name evidence="6" type="ORF">A0J61_06752</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000423">
        <property type="protein sequence ID" value="OBZ85190.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N7T7"/>
    <dbReference type="STRING" id="101091.A0A1C7N7T7"/>
    <dbReference type="InParanoid" id="A0A1C7N7T7"/>
    <dbReference type="OrthoDB" id="26525at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00051">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.238.10:FF:000181">
        <property type="entry name" value="CALML5 isoform 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050145">
        <property type="entry name" value="Centrin_CML-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23050">
        <property type="entry name" value="CALCIUM BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13499">
        <property type="entry name" value="EF-hand_7"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00054">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0106">Calcium</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="EF-hand" evidence="5">
        <location>
            <begin position="21"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="5">
        <location>
            <begin position="96"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="5">
        <location>
            <begin position="132"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="55"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="69"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OBZ85190.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="174" mass="20232" checksum="93259B9BE3925746" modified="2016-11-30" version="1" fragment="single">HNGFIKLSQFGDILKSLNIEHDAKKLETIVKKSDKNHDGRIDFDEFVSVMTHFLPPQYTDEPEQVEEANDNKNRTRDINSNRQKSRERYSRCMSRHETEEMKMCFSKFDKNGDGQISEAELKEVMNDLGENLSDQEIKDMMNDADTNKDGFIDFNEFAALAPKMGEEEKTKQTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N815</accession>
    <name>A0A1C7N815_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein C31F10.16</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_06759</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000423">
        <property type="protein sequence ID" value="OBZ85197.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="FunCoup" id="A0A1C7N815">
        <property type="interactions" value="29"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N815"/>
    <dbReference type="InParanoid" id="A0A1C7N815"/>
    <dbReference type="OrthoDB" id="434695at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034044">
        <property type="term" value="C:exomer complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006893">
        <property type="term" value="P:Golgi to plasma membrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.10:FF:000149">
        <property type="entry name" value="Clathrin-coated vesiclec protein (Bud7)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015374">
        <property type="entry name" value="ChAPs"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31975">
        <property type="entry name" value="BUD SITE SELECTION PROTEIN 7-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31975:SF1">
        <property type="entry name" value="BUD SITE SELECTION PROTEIN 7-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09295">
        <property type="entry name" value="ChAPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="449"/>
            <end position="476"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ85197.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="652" mass="74984" checksum="23F3A40B04C3F605" modified="2016-11-30" version="1">MADTLKDIPEFFEHDLGESIIARTDALGTFRELGPPDLCHIIKVNAKPGTKEIGSYHYISGVDASSSATLAAYLNSLTYSMDETQSWFTKSNSWRIRSGIYCCYNAFSRIDIRVEVKIPGGVETYYVGVRGERHEATTEMWQETYVSAILRAILYSDDSYYRLAGYRKIDPITSIESETRFLEAVENLFWKGSQLGSKPEVQVATSVHNHLADGVMKYFGDSFRYGPAIELFEKLHKRDPEVGALLATSFVGYNEEIKAVKVLYEDLKLAPTSFSLIHTQVDFLRSKSDYETALKLAKYAVNTTPSEYLTWAKLTEVYIDLKDYKNALLTLNSCPMFTYSERDMHRMPPPQKTHLPIKPEIVSSGIMEEDXVGRESEADPAIARLPAPALHGTFAKAYSLLTKLVNALGWDELLQYRSEVFVMEDEYRKHKAKEEYRKSAAINPEEVAKKLQEANLNELEKPKQAAEDEHPSAEQEVTLSFGNKRLCERWLDNLFMVLYEDLRVYTHWRTESAHYKMQKLNYRKTGTEWEMLGDLSLRLWHEKEAKEAYELCLDHKFSAKAWMRLLNIYSSEGNTQKALLAAVKLTVYHERWYHEIVYPTEIARNLNTLIRKVGLSKMQNILTSMNLPKPVQKLMTRYFKNGLLFQVEGYDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N8T6</accession>
    <name>A0A1C7N8T6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Ras-specific guanine nucleotide-releasing factor RalGPS1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">ralgps1_1</name>
        <name evidence="6" type="ORF">A0J61_08190</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000608">
        <property type="protein sequence ID" value="OBZ83764.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N8T6"/>
    <dbReference type="STRING" id="101091.A0A1C7N8T6"/>
    <dbReference type="InParanoid" id="A0A1C7N8T6"/>
    <dbReference type="OrthoDB" id="546434at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005085">
        <property type="term" value="F:guanyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007265">
        <property type="term" value="P:Ras protein signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.840.10">
        <property type="entry name" value="Ras guanine-nucleotide exchange factors catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008937">
        <property type="entry name" value="Ras-like_GEF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023578">
        <property type="entry name" value="Ras_GEF_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001895">
        <property type="entry name" value="RASGEF_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036964">
        <property type="entry name" value="RASGEF_cat_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23113:SF368">
        <property type="entry name" value="CELL DIVISION CONTROL PROTEIN 25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23113">
        <property type="entry name" value="GUANINE NUCLEOTIDE EXCHANGE FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00617">
        <property type="entry name" value="RasGEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00147">
        <property type="entry name" value="RasGEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48366">
        <property type="entry name" value="Ras GEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50009">
        <property type="entry name" value="RASGEF_CAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1 2" id="KW-0344">Guanine-nucleotide releasing factor</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ras-GEF" evidence="5">
        <location>
            <begin position="268"/>
            <end position="507"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="472"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="609"/>
            <end position="667"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="690"/>
            <end position="711"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="195"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="609"/>
            <end position="627"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="634"/>
            <end position="646"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="647"/>
            <end position="656"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="701"/>
            <end position="711"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022658"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00168"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50009"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OBZ83764.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="711" mass="78877" checksum="A8E11E98912FBB2E" modified="2016-11-30" version="1">MEDIQSSLAIASHQFDKGQIKDAYSIFLATAQSALQPLFDTKFVRSSVVSKPQDSTALISALHLCLDHIEKILEYHSVSAKVPPPPIPPKPTLVGKPALPPKPSTVAAPVPIPSRVTVKRSLSDHEIIVTQQREQQRTYTRSNLCSMDEAVPDGEVDPNHLVPAQTNSNDSLPNATAAKIDHVPNIPVPPLLTSHRMLQSKLDELESSLKEFRLQKTQLGIQDTQKIYELDAAIAKYTPYVAEAKHTLNRVRTLYMSAATIPSILHFQPALVAYQLTRIESAIFMAIPPHALLTHSPKSPHSRIVASSDFFNYITRWIEHSILLPQEASIRSQHINHWIKIAWKCQELNNYQTLKAIVSALGTPPVQRLKRTWAYIPKKSLARLDTMNELMSETNNYGRYREHMGIVSTAVLNGKSVDSIQSEHLKKPTVPFLGTFIHDMTYLLAAVNQEQKEKDPRILKLLEILGKFQSTPTYHRKPSSNVLKKSQSQVRPSLSQAIHRSKSSFGRLGGAIGFGGSHTDNSSTGDASNANFSDTADDFNAEEQQSLVTQYILMRPWVNQTMVDELSLLREPPTNTKCTGRANSISNSVMSTTSSLMLLGNQNYTTSSAPIINSSRPTSLDDPTSRSYIYGRGSAQSSIPLTSSSTFEDEDEDEEVLSSPASTSYPVILSPKSDSQHFWSDPVINMYNKEAAPMVPPRPSPSYRSNPSFRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N8X0</accession>
    <name>A0A1C7N8X0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uracil-regulated protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">urg1</name>
        <name evidence="8" type="ORF">A0J61_06933</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the GTP cyclohydrolase II family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000442">
        <property type="protein sequence ID" value="OBZ85026.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N8X0"/>
    <dbReference type="STRING" id="101091.A0A1C7N8X0"/>
    <dbReference type="InParanoid" id="A0A1C7N8X0"/>
    <dbReference type="OrthoDB" id="57939at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003935">
        <property type="term" value="F:GTP cyclohydrolase II activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009231">
        <property type="term" value="P:riboflavin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00641">
        <property type="entry name" value="GTP_cyclohydro2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10990">
        <property type="entry name" value="GTP cyclohydrolase II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022163">
        <property type="entry name" value="GTP_CH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032677">
        <property type="entry name" value="GTP_cyclohydro_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000926">
        <property type="entry name" value="RibA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036144">
        <property type="entry name" value="RibA-like_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF005536">
        <property type="entry name" value="PRK07198.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47259">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47259:SF2">
        <property type="entry name" value="URACIL-REGULATED PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12471">
        <property type="entry name" value="GTP_CH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00925">
        <property type="entry name" value="GTP_cyclohydro2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF142695">
        <property type="entry name" value="RibA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GTP cyclohydrolase N-terminal" evidence="7">
        <location>
            <begin position="82"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="domain" description="GTP cyclohydrolase II" evidence="6">
        <location>
            <begin position="314"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="4"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008131"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00925"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF12471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OBZ85026.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="497" mass="54978" checksum="95823410B08F6890" modified="2016-11-30" version="1">MTVSADEEAVLQKMLATMNNLREEQSRLAEQIDKFTLSSDANKPAQLSPSTSITAITTDEAVVGTESIPDNSSPFTPSYPSRVILTTYPGQQGIKPLTLNWGAKSPHERGPIVASRHAESIKKRNAIGAYGGSYCIYRALAVAIGDLPSNHRPNFDMTEPVYQVGPHPSWFDPEKIVSLDPFGHIAPSIFKEEYEKGLDVRPTIAITRAHMTMAEMEMSVKNGTLQVDGKIVVNNRGDLSVSKAAVEPVWYLPGVAKRFGIEESLLRRALFEDTGGMYPELITRPDLKVFLPPIGGISIYIFGNPEYISDTSKKLTLRVHDECNGSDVFGSDICTCRPYLIYGIEECAKQAQQGGVGVIVYFRKEGRALGEVTKYLVYNARKRQTGGDTASNYFLRTECIAGVKDMRFQALMPDVLHWLGIKKIDRMMSMSNMKYEAIVGSGIPIVERVPIPEELIPDDSRVEIDAKIAAGYFTSGTALTNEELTQVKGRDWEDIEH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N985</accession>
    <name>A0A1C7N985_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Cytochrome b-c1 complex subunit 2, mitochondrial</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">qcr-2</name>
        <name evidence="13" type="ORF">A0J61_06263</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
            <orientation evidence="1">Matrix side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the peptidase M16 family. UQCRC2/QCR2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000370">
        <property type="protein sequence ID" value="OBZ85692.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N985"/>
    <dbReference type="FunCoup" id="A0A1C7N985">
        <property type="interactions" value="273"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N985"/>
    <dbReference type="InParanoid" id="A0A1C7N985"/>
    <dbReference type="OrthoDB" id="6369905at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.830.10:FF:000021">
        <property type="entry name" value="Cytochrome b-c1 complex subunit 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.830.10:FF:000039">
        <property type="entry name" value="Ubiquinol-cytochrome c reductase core subunit 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.830.10">
        <property type="entry name" value="Metalloenzyme, LuxS/M16 peptidase-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011249">
        <property type="entry name" value="Metalloenz_LuxS/M16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050361">
        <property type="entry name" value="MPP/UQCRC_Complex"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011765">
        <property type="entry name" value="Pept_M16_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007863">
        <property type="entry name" value="Peptidase_M16_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11851:SF209">
        <property type="entry name" value="CYTOCHROME B-C1 COMPLEX SUBUNIT 2, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11851">
        <property type="entry name" value="METALLOPROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00675">
        <property type="entry name" value="Peptidase_M16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05193">
        <property type="entry name" value="Peptidase_M16_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63411">
        <property type="entry name" value="LuxS/MPP-like metallohydrolase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0249">Electron transport</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="4" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0679">Respiratory chain</keyword>
    <keyword evidence="5" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Peptidase M16 N-terminal" evidence="11">
        <location>
            <begin position="36"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M16 C-terminal" evidence="12">
        <location>
            <begin position="189"/>
            <end position="356"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022660"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00038146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00040751"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00675"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF05193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="OBZ85692.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="477" mass="49425" checksum="20F88FC5930A1852" modified="2016-11-30" version="1">MLAASRKAIISTASKATYATAATANQISTAANGIKVVSSQEPGQTASLAVVVNGGARAESANNAGAAHFLKNYGFKNNANRTAFRIAREAELAGGVLSSNVSHEALVYSAELLKEDVELFAELLGDVVTKQKFQEHEFLDVARQTAAESASAFSNSEITAIEAAHQTAFRTGLGNSIFAKPTAHAKNATVKAFAQQLFIQGNIALVGTGVEHETLEHLAETYFNLPAGNLNLASTKYYGGESRIESVSANGQYVLAFEGAAANSAEYAALQVLRFALGGEAVVKNTAASGILAQTSAKFSDASIKAFNLGYSDAGLFGVQVSASTSEAEAAVAAAAEQLKAAKNLSSEDFSRAVAQAKFAATANIQTRLDRAEALGVYALQNGKYASTSEAIAAIEKVSASDVAQAAEKLFKSKLTTIALGDLSLVVIGAHVDDNRIVIIDVVDVFGVTLCGYTIALTVGTGTSIGFGTKIEIEVTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N9A3</accession>
    <name>A0A1C7N9A3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">GST C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_06442</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000389">
        <property type="protein sequence ID" value="OBZ85508.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N9A3"/>
    <dbReference type="STRING" id="101091.A0A1C7N9A3"/>
    <dbReference type="InParanoid" id="A0A1C7N9A3"/>
    <dbReference type="OrthoDB" id="202840at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00299">
        <property type="entry name" value="GST_C_family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00570">
        <property type="entry name" value="GST_N_family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1050.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010987">
        <property type="entry name" value="Glutathione-S-Trfase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036282">
        <property type="entry name" value="Glutathione-S-Trfase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004045">
        <property type="entry name" value="Glutathione_S-Trfase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004046">
        <property type="entry name" value="GST_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050983">
        <property type="entry name" value="GST_Omega/HSP26"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43968">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43968:SF6">
        <property type="entry name" value="GLUTATHIONE S-TRANSFERASE OMEGA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14497">
        <property type="entry name" value="GST_C_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13417">
        <property type="entry name" value="GST_N_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47616">
        <property type="entry name" value="GST C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50405">
        <property type="entry name" value="GST_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GST C-terminal" evidence="1">
        <location>
            <begin position="52"/>
            <end position="187"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ85508.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="195" mass="22622" checksum="A94A890E59282227" modified="2016-11-30" version="1">MDNSEDSSLVLYTHEVSPWGDRAVAILREANLKFEYVVLNPFQAPEWLMPSEPIKRAKVRFASNYFAEKINPIMRACATDFHNKQTQATYKQQVTEFFYKFHEMLLEQAPTGPYFLGQSFSLADVAISPFFLRLQSFNKLCFDGFGDDILKECPRLLEFYQGISSRPSSQETFMGDKAFIDFQDSIFHFFQKPSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N9H8</accession>
    <name>A0A1C7N9H8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Putative NADPH dehydrogenase C23G7.10c</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">A0J61_06352</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000380">
        <property type="protein sequence ID" value="OBZ85598.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N9H8"/>
    <dbReference type="FunCoup" id="A0A1C7N9H8">
        <property type="interactions" value="1"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N9H8"/>
    <dbReference type="InParanoid" id="A0A1C7N9H8"/>
    <dbReference type="OrthoDB" id="72788at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003959">
        <property type="term" value="F:NADPH dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02932">
        <property type="entry name" value="OYE_YqiM_FMN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001155">
        <property type="entry name" value="OxRdtase_FMN_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044152">
        <property type="entry name" value="YqjM-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43303">
        <property type="entry name" value="NADPH DEHYDROGENASE C23G7.10C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43303:SF4">
        <property type="entry name" value="NADPH DEHYDROGENASE C23G7.10C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00724">
        <property type="entry name" value="Oxidored_FMN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51395">
        <property type="entry name" value="FMN-linked oxidoreductases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="3" id="KW-0288">FMN</keyword>
    <keyword evidence="4" id="KW-0521">NADP</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NADH:flavin oxidoreductase/NADH oxidase N-terminal" evidence="6">
        <location>
            <begin position="27"/>
            <end position="374"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00724"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OBZ85598.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="411" mass="44917" checksum="DDB655AC26F88B74" modified="2016-11-30" version="1">MPIPAAAANEKKPAGVPVHAKDIERVKLFQPYQKKSVTTHNRLGVSPMCMYSADDGYVNDFHLGHYLSFALKGPGLVMVEASGVTPEGRITPGCLGIWDDSHIEGMKKLSDNIKSQGSKSAIQIAHAGRKASTSPPFLGDYVMDEANGGWPNRVVGPSDNAFAPHYATPHALTKEEIKQHVQAFADAAVRVNKAGFDILEIHGAHGYLISSFYSGSSNKRTDEYGGSFENRIRFALEVAQAVRDVWPQEKPLWMRLSCSDYSNPDPMGHSPDGWDIYQTIELAKELKKIGVDVIDCSSGGIIPGVKYPSNPMYQVPLAEAIKKGADIDTAAVGLIVEGEDAEGILQKGQADFILAAREFLRDSAFVLRAAQSLDVEIVWPKQYSWAVKKARRDSVIKAPKELDEQEKKSVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N9L6</accession>
    <name>A0A1C7N9L6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">1-phosphatidylinositol 4-kinase</fullName>
            <ecNumber evidence="4">2.7.1.67</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="primary">stt4_1</name>
        <name evidence="15" type="ORF">A0J61_06190</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol 4-phosphate) + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:19877"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57880"/>
            <dbReference type="ChEBI" id="CHEBI:58178"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.67"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the PI3/PI4-kinase family. Type III PI4K subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.67" evidence="4"/>
    <dbReference type="EMBL" id="LUGH01000362">
        <property type="protein sequence ID" value="OBZ85767.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="FunCoup" id="A0A1C7N9L6">
        <property type="interactions" value="293"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N9L6"/>
    <dbReference type="InParanoid" id="A0A1C7N9L6"/>
    <dbReference type="OrthoDB" id="10264149at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004430">
        <property type="term" value="F:1-phosphatidylinositol 4-kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046854">
        <property type="term" value="P:phosphatidylinositol phosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048015">
        <property type="term" value="P:phosphatidylinositol-mediated signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05167">
        <property type="entry name" value="PI4Kc_III_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.70:FF:000011">
        <property type="entry name" value="Phosphatidylinositol 4-kinase alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1010.10:FF:000014">
        <property type="entry name" value="Phosphatidylinositol 4-kinase STT4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1070.11:FF:000005">
        <property type="entry name" value="Phosphatidylinositol 4-kinase, catalytic, alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1070.11">
        <property type="entry name" value="Phosphatidylinositol 3-/4-kinase, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1010.10">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.70">
        <property type="entry name" value="Phosphatidylinositol 3-kinase, accessory domain (PIK)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018501">
        <property type="entry name" value="DDT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015433">
        <property type="entry name" value="PI3/4_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000403">
        <property type="entry name" value="PI3/4_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036940">
        <property type="entry name" value="PI3/4_kinase_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018936">
        <property type="entry name" value="PI3/4_kinase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001263">
        <property type="entry name" value="PI3K_accessory_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042236">
        <property type="entry name" value="PI3K_accessory_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045495">
        <property type="entry name" value="PI4K_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028942">
        <property type="entry name" value="WHIM1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028941">
        <property type="entry name" value="WHIM2_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10048:SF15">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL 4-KINASE ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10048">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02791">
        <property type="entry name" value="DDT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00454">
        <property type="entry name" value="PI3_PI4_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00613">
        <property type="entry name" value="PI3Ka"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19274">
        <property type="entry name" value="PI4K_N"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15612">
        <property type="entry name" value="WHIM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15613">
        <property type="entry name" value="WSD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00145">
        <property type="entry name" value="PI3Ka"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00146">
        <property type="entry name" value="PI3Kc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50827">
        <property type="entry name" value="DDT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00915">
        <property type="entry name" value="PI3_4_KINASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00916">
        <property type="entry name" value="PI3_4_KINASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50290">
        <property type="entry name" value="PI3_4_KINASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51545">
        <property type="entry name" value="PIK_HELICAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7 15" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="DDT" evidence="13">
        <location>
            <begin position="291"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="domain" description="PIK helical" evidence="14">
        <location>
            <begin position="2242"/>
            <end position="2420"/>
        </location>
    </feature>
    <feature type="domain" description="PI3K/PI4K catalytic" evidence="12">
        <location>
            <begin position="2497"/>
            <end position="2785"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="23"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="373"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="552"/>
            <end position="662"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="10">
        <location>
            <begin position="196"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="23"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="373"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="406"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="552"/>
            <end position="566"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="567"/>
            <end position="595"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="596"/>
            <end position="662"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001686"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51545"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="OBZ85767.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="2801" mass="322089" checksum="63E782637EA47D2D" modified="2016-11-30" version="1">MNGYTYVAKIVDLLPGRVVVQHENPQSQSSLPNSESQNTATDEPEDDATNVPRQPNGRLRFPDAFLLPTPQLPHIQPRPQHEPNDPIDNCMVEERQYKVQLLNEVGQPLENCRRIVLEHQLDRDRLIFNRLNVQSFIRECASKEAYFNAPWLVKPSLAVTYGIDTTIPHHLQHLHDQFYPQSSRKRKIAPFKTAVDREAEKRARRQESMLQKAKLKEERDRLREEKRKQAAIKYPIEDLDLPIYRKNPNLNWALIDMHPQKYDAKEDSIIPYPSGGRSERPQPHHDSLIPPELFDIFLSIWAFLTVFSEPLKLTAYSIDDFERALFHNTHQPKATVLVEYNACLLNVIISERKEDTANELINGEVMEIYVESLEEENEENEEEEEENEKENEKQRNSRKRSLREGSVQSDTSQQRNPPVLPRVERGWRDKEHLRIAQKWDHKELRANYDRRGWETTLIGCLNDVATPELLPNVDELLQHLVPKMNSSAADREKQYPTLSVKQKLDILSFLIDTVNESSLIKNYMDYCQDQLSEFRKQKMELNKESKALAIKRSEMDKRDKAEKFDELSEEQSDDDDDSSSSDHSDDDNMDMESDSSDTRLANREKRHQSRQEKLRQKQREREEQEKQRKKQYAEQREVAKAKSQEQRIKANERRKLEEEERNLKKKEENIERSMRRYMTLRIRPLGKDRFNHRYFYLDNVGVSNTYGSGRLYVHSPSDGDILLMMERDSRTDLPEQPWGYGGGRWFIKKLMHEQGLAEESEWLERRMDELNADPTKEYRGWWKYYSKPEEIEQLLGWLNPKGVRENKLKSELVKQQPYIIESITKRTQALNKPESVVKLSLASVLADSRAKTTTDEVAQLLSKCPDIPLVDMNDLTIITSLEDKQNIGQLTTRYQKTLEAFVKYVVETNASKQSEHVPRILSFLKHLPVLEWDNVLTTKGSTPPDRATYSLVLGLLQIAHQQPELSKTIYGTLWNYGRCIVDLMETRDKDYIISFILPSLAGLARALQVSPFLHKPDQLQSLCENVQPLIVDKTLDRVKTAIDECLKESDKDSYSRRVLANYWEAGIPLSANRIIHDLLIILRNVTARVIAVSYPAQTARESSVDPNKLHLTVHIEHAWSDLMKRVAEGVRPQQEGLSDVDKKLNKNLRGAYVMSLGYFEDIKKYAAKRDNEGKNWALDSYMTEIVGTSLQVAALSSVYLHEVDDVLIDYVEECLFEFPVKNDAWVHVASLDTAVLLAINFPSLGNKMTETVCRYLATPSPVFELNTQIEQTKMTMQKFAIIRLAQCIQTKQELQMRQAANSTFYALLNEITRFSEQDDTNNHAPLLRSNSISGAPSSQSLNEAQKQQVRVNALSAIVGVAVYLKDEAIIAQAYSVLALRRKSFSVSTITTLTKSLVDLALVSNLSVFRDITNLFSVLSRESLLTDDKQLSTAILDAQLALAQQLSSQPRHYDCYLSNLLGLFVENGNTIQRVMAKNKDQSDIPLASKLGRILPVIRALLEHSDFEPHLSPSEETVSLFRNTWFQCVLFGFVTESIWIREWHDSMLIIAKKTPVLVIESATNYLESDLEYNSVLRGSSISDRDIGLMRQKLTNLLPALAYDSKNFSFAQIVFALSVYHIEVMRSKTGDCSFILRYFMNDGVSNSTMANCLENILERTTANYIKDATAKASSQNLNNELRTQMSHLLQLCCHRLDKVHSLAVKTSDRIVTAFPQVFAEKSLITLLLELVQLLWLSCEAEYRDEYYPTFHFTSTRVGVTIELGDSFAYRRNLCSHMYENGKKWLQLSMDRTPMEINGLLQDYLAEYVRYEPDAPIDVAHMGRTLALEVGKAAAKSEMTINFVPRVRGALLDDSSDFVDGFTSRRYHIGEVSGIQRMSNHHSKASQDTEVANLEDQIPFVLQTLQTLMENVKQQKKIPVDHLRRTLLQAASFIASLPSVHPDLIAPIVRIPVHIFTPESLEIGTDVWNWILVERPDVEKRLMVEILNMWSWAQRYRKGLFSPRLNSKHPFVSKMTYAPSDRAIIDTNNHNMTRLFTPHVTWIKFLTSRFYAIRHRSKHLINMLVRLLQVAFQNSHLMSTHPFARLARFQLLTLGMKILRSSQMEALSEYRFRSLVYGSAFDWFALPPMWHYGSRKSYALVEQKVLTDFHSTVANDYPRLTDLVTSTSSRNSQSKVASGLYMFLSDKTKDDILREHKMTKRLLLLLLDNELSRLSVWCNPLNAVGPGYPNNYVGSSDKSLSTDDSWKEIIRFAWQTSPKVAVQMAARFVQPSVQRELHTLIANNTLDVVDVPEALEILLGDKVQPNAKLDLRYLKYWAPVPAITAANYFMPAYGNHPLILQYAMRSLEYYPVDTVFFYVPQIVQALRYDEFGYVERYIMEAGQVSQLFAHQIIWNMSANFYIDADKDCVKPDPLKPTLEKIIDNLVSSFTGEDREFYEREFKFFGDVTAISGYLKEYIKYGQNEKKPMQKKRLDEELAKIKVDVGVYLPSNPDGHVVDINRNSGRPLQSHAKAPFMATFKIEKEKEHIESIDDSNDNASEKSSVTLWQSAIFKVGDDCRQDVLALQLIAVFKNIFTSIGMDLYVYPYRVVATAPGRGVIDVIPRSISRDQLGREKVNSMYDYFVAKYGAPSSIAFQRARTNFVQSVAAYSLISYLLQFKDRHNGNIMLDDDGHIIHIDFGFIFDIAPGGIGFESSPFKLTTEMVQVMGGNSEEQAFKQFSELVIKGYLACRPYAELIMQLVTLMLQSGLPCFRGETIKRMRARFQSDKSDRAAADFMIQRVKDSFENQRTVLYDYFQKVTNGIPY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NA60</accession>
    <name>A0A1C7NA60_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Histone-lysine N-methyltransferase, H3 lysine-4 specific</fullName>
            <ecNumber evidence="3">2.1.1.354</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="14">SET domain-containing protein 1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="23" type="primary">set1</name>
        <name evidence="23" type="ORF">A0J61_07704</name>
    </gene>
    <organism evidence="23 24">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="23" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="23">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="15">
            <text>L-lysyl(4)-[histone H3] + 3 S-adenosyl-L-methionine = N(6),N(6),N(6)-trimethyl-L-lysyl(4)-[histone H3] + 3 S-adenosyl-L-homocysteine + 3 H(+)</text>
            <dbReference type="Rhea" id="RHEA:60260"/>
            <dbReference type="Rhea" id="RHEA-COMP:15537"/>
            <dbReference type="Rhea" id="RHEA-COMP:15547"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29969"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:61961"/>
            <dbReference type="EC" id="2.1.1.354"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="17">
            <text>N(6),N(6)-dimethyl-L-lysyl(4)-[histone H3] + S-adenosyl-L-methionine = N(6),N(6),N(6)-trimethyl-L-lysyl(4)-[histone H3] + S-adenosyl-L-homocysteine + H(+)</text>
            <dbReference type="Rhea" id="RHEA:60272"/>
            <dbReference type="Rhea" id="RHEA-COMP:15537"/>
            <dbReference type="Rhea" id="RHEA-COMP:15540"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:61961"/>
            <dbReference type="ChEBI" id="CHEBI:61976"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="16">
            <text>N(6)-methyl-L-lysyl(4)-[histone H3] + S-adenosyl-L-methionine = N(6),N(6)-dimethyl-L-lysyl(4)-[histone H3] + S-adenosyl-L-homocysteine + H(+)</text>
            <dbReference type="Rhea" id="RHEA:60268"/>
            <dbReference type="Rhea" id="RHEA-COMP:15540"/>
            <dbReference type="Rhea" id="RHEA-COMP:15543"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:61929"/>
            <dbReference type="ChEBI" id="CHEBI:61976"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Chromosome</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="23">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.354" evidence="3"/>
    <dbReference type="EMBL" id="LUGH01000536">
        <property type="protein sequence ID" value="OBZ84244.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NA60"/>
    <dbReference type="FunCoup" id="A0A1C7NA60">
        <property type="interactions" value="76"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NA60"/>
    <dbReference type="InParanoid" id="A0A1C7NA60"/>
    <dbReference type="OrthoDB" id="308383at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005694">
        <property type="term" value="C:chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048188">
        <property type="term" value="C:Set1C/COMPASS complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140999">
        <property type="term" value="F:histone H3K4 trimethyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd19169">
        <property type="entry name" value="SET_SETD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.170.270.10:FF:000010">
        <property type="entry name" value="Histone-lysine N-methyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.270.10">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024657">
        <property type="entry name" value="COMPASS_Set1_N-SET"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003616">
        <property type="entry name" value="Post-SET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044570">
        <property type="entry name" value="Set1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024636">
        <property type="entry name" value="SET_assoc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001214">
        <property type="entry name" value="SET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046341">
        <property type="entry name" value="SET_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037841">
        <property type="entry name" value="SET_SETD1A/B"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45814">
        <property type="entry name" value="HISTONE-LYSINE N-METHYLTRANSFERASE SETD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45814:SF2">
        <property type="entry name" value="HISTONE-LYSINE N-METHYLTRANSFERASE SETD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11764">
        <property type="entry name" value="N-SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00856">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11767">
        <property type="entry name" value="SET_assoc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01291">
        <property type="entry name" value="N-SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00508">
        <property type="entry name" value="PostSET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00317">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82199">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50868">
        <property type="entry name" value="POST_SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50280">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="9" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="5" id="KW-0158">Chromosome</keyword>
    <keyword evidence="6 23" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="13" id="KW-0539">Nucleus</keyword>
    <keyword evidence="24" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10 18" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="8" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="12" id="KW-0804">Transcription</keyword>
    <keyword evidence="11" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="7 23" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="RRM" evidence="20">
        <location>
            <begin position="94"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="domain" description="SET" evidence="21">
        <location>
            <begin position="1053"/>
            <end position="1170"/>
        </location>
    </feature>
    <feature type="domain" description="Post-SET" evidence="22">
        <location>
            <begin position="1176"/>
            <end position="1192"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="19">
        <location>
            <begin position="190"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="19">
        <location>
            <begin position="497"/>
            <end position="516"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="19">
        <location>
            <begin position="527"/>
            <end position="549"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="19">
        <location>
            <begin position="643"/>
            <end position="947"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="19">
        <location>
            <begin position="204"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="19">
        <location>
            <begin position="253"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="19">
        <location>
            <begin position="277"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="19">
        <location>
            <begin position="288"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="19">
        <location>
            <begin position="301"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="19">
        <location>
            <begin position="323"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="19">
        <location>
            <begin position="350"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="19">
        <location>
            <begin position="497"/>
            <end position="508"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="19">
        <location>
            <begin position="645"/>
            <end position="669"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="19">
        <location>
            <begin position="683"/>
            <end position="694"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="19">
        <location>
            <begin position="733"/>
            <end position="753"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="19">
        <location>
            <begin position="769"/>
            <end position="782"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="19">
        <location>
            <begin position="786"/>
            <end position="798"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="19">
        <location>
            <begin position="828"/>
            <end position="840"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="19">
        <location>
            <begin position="848"/>
            <end position="865"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="19">
        <location>
            <begin position="873"/>
            <end position="884"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="19">
        <location>
            <begin position="885"/>
            <end position="896"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="19">
        <location>
            <begin position="897"/>
            <end position="912"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="19">
        <location>
            <begin position="938"/>
            <end position="947"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012182"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00015839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00030093"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00047571"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00047583"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00049129"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="21">
        <source>
            <dbReference type="PROSITE" id="PS50280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="22">
        <source>
            <dbReference type="PROSITE" id="PS50868"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="EMBL" id="OBZ84244.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="24">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="1192" mass="136367" checksum="9C2487EAE8458F09" modified="2016-11-30" version="1">MDSKWSSSTTGKGPRNYKCIYDPELDTQGLRTSTQAQYQYEDEQAAITIGPRDPRVDKQTYERGFSKHRLLYKKHFSVVTYKFDNNSVGPKPPTTVLASRLSPLMTETQIMTYFSVYGQVASVEIVKCPTTGGSLGIAHISFASDELSDGHASACLAVEKGNGRQMGAAEHVKVCFDPTGDKLKLAIADADNDTKKGPSNRHGPSTPMSSSSSNAPATTATAVASPHRSATPINTHSRNSRHEYPGGSNELNEWDRYSHDSRRYSRYSPREDYHRPSNYNGRSNSNGYHDDYKYRDERPSSRYHHHPPPHHHYGHHYPPPLPSSRYSSSRHYSQYTSNSHRAESPHHYSSRWTRSPSMSSHDSIRYKSRSRSRSRSLERRDSYYESDWRGRRKHSDYWENRPLYEDSRRSSSSAIPPSSRPILAISRKCLPFVRGVLEDLKKMFYYYNCIDIYHDEADWLIVFDSLTIAKKALDATNDQQLMGYKLLITLRHPSVNNSTNHVNNNSSNLDKPSTATTIIDTPSISAETDSIDTPAQEEPTQKTVNGVDEHTPIPVTAHDLFLNELVDVFLKDLKNRVAGPSIHDFLKTARSSRKIQIDTSATAVLTEEKDLPKTQVIQSILNTSKLPRFKKKKTIQYRRRLSLIDDSEDDEEEEEEEEGESMDESEEEMEQSRQERRRFKSTHIADRDWNRKEFTNLPANQQQDEEAAVALDEKMFSSSEEGEYRSDDEDAMEKDSPSPRIDDSRPRRLRDYLSDDGSSVDEHDAFLKQLQQQQQNESQSELAGSESDRDDFVEHDLQESPIQRKRKSSAIVSGLKKPSKKLKKTLSYEDEDDMDDDYDDFSSYNIPKKQKKQQQAMQKKKKVKPVKPPMPERVYEIIEEDLSKDISSGSSNSSIVGEEEEDREEEEEMDQEAIERALLASDESDSEELKELNQDSGEPPEFDPFEQIDDPEDYWFLRAFLLERAGIPLTEPVTNVIKGGCARARGYYKIPDAMKATYLPRNTAVIDIPSDTTRISSRATRVNNRRIVMGMEMQKKTIDSDILKFNQLKSRKKQLRFAKSPIHDWGLYAEEHIDANDMVIEYVGEMIRQQVAEEREKKYERCGIGSSYLFRVDDDTVIDATKCGNVARFINHCCAPNCSAKIITVDKQKKIVIYANRDIEPGEEITYDYKFPIEADKIPCLCGSKYCKGTLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NA85</accession>
    <name>A0A1C7NA85_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Protein sco1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">sco1_0</name>
        <name evidence="4" type="ORF">A0J61_07693</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SCO1/2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000534">
        <property type="protein sequence ID" value="OBZ84264.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NA85"/>
    <dbReference type="STRING" id="101091.A0A1C7NA85"/>
    <dbReference type="InParanoid" id="A0A1C7NA85"/>
    <dbReference type="OrthoDB" id="270009at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033617">
        <property type="term" value="P:mitochondrial respiratory chain complex IV assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02968">
        <property type="entry name" value="SCO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003782">
        <property type="entry name" value="SCO1/SenC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12151:SF5">
        <property type="entry name" value="AT19154P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12151">
        <property type="entry name" value="ELECTRON TRANSPORT PROTIN SCO1/SENC FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02630">
        <property type="entry name" value="SCO1-SenC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0186">Copper</keyword>
    <keyword evidence="3" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="2">
        <location>
            <position position="140"/>
        </location>
        <ligand>
            <name>Cu cation</name>
            <dbReference type="ChEBI" id="CHEBI:23378"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="144"/>
        </location>
        <ligand>
            <name>Cu cation</name>
            <dbReference type="ChEBI" id="CHEBI:23378"/>
        </ligand>
    </feature>
    <feature type="disulfide bond" description="Redox-active" evidence="3">
        <location>
            <begin position="140"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="183"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010996"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR603782-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR603782-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OBZ84264.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="183" mass="20786" checksum="4C92380EEB1CD4D7" modified="2016-11-30" version="1" fragment="single">MSTTRLIQHVLKTPIRRPITNIRKSPLAPIPFNYAKPTSIRHHAYGTKAPPTPPPPKTFTWKSAVVLALTATGLVVYFKGEKEKLMAQRKRQERDSIRALGRPHIGQPFRLLNVNEKRVMSSEELMEGQFTMIYFGFTHCPDICPEELDKMAEVTDAVKAEFGEGILRPVFITCDPLRDTEEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NAG4</accession>
    <name>A0A1C7NAG4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">RING-type E3 ubiquitin transferase</fullName>
            <ecNumber evidence="4">2.3.2.27</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="primary">doa10_0</name>
        <name evidence="16" type="ORF">A0J61_06334</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.</text>
            <dbReference type="EC" id="2.3.2.27"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.27" evidence="4"/>
    <dbReference type="EMBL" id="LUGH01000378">
        <property type="protein sequence ID" value="OBZ85616.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NAG4"/>
    <dbReference type="FunCoup" id="A0A1C7NAG4">
        <property type="interactions" value="607"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NAG4"/>
    <dbReference type="InParanoid" id="A0A1C7NAG4"/>
    <dbReference type="OrthoDB" id="264354at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036503">
        <property type="term" value="P:ERAD pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd16702">
        <property type="entry name" value="RING_CH-C4HC3_MARCH6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.40.10:FF:000287">
        <property type="entry name" value="RING finger membrane protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056521">
        <property type="entry name" value="MARCHF6-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011016">
        <property type="entry name" value="Znf_RING-CH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13145:SF0">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE MARCHF6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13145">
        <property type="entry name" value="SSM4 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23113">
        <property type="entry name" value="MARCHF6_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12906">
        <property type="entry name" value="RINGv"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00744">
        <property type="entry name" value="RINGv"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51292">
        <property type="entry name" value="ZF_RING_CH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="12 14" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="6 14" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="11 14" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="9" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="10" id="KW-0862">Zinc</keyword>
    <keyword evidence="8" id="KW-0863">Zinc-finger</keyword>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="88"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="180"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="439"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="571"/>
            <end position="593"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="619"/>
            <end position="642"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="671"/>
            <end position="691"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="729"/>
            <end position="751"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="771"/>
            <end position="794"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="936"/>
            <end position="960"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="980"/>
            <end position="1001"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="1034"/>
            <end position="1056"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="1076"/>
            <end position="1094"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="1123"/>
            <end position="1143"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="1163"/>
            <end position="1182"/>
        </location>
    </feature>
    <feature type="domain" description="RING-CH-type" evidence="15">
        <location>
            <begin position="3"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="249"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="293"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="293"/>
            <end position="308"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51292"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="OBZ85616.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="1208" mass="138021" checksum="401BD37EF08D17B5" modified="2016-11-30" version="1">MRETEDEEEICRVCRSEATPEQPLFHPCKCAGSIRYVHQDCLTEWLAHSRKKYCELCEHPFNFTPVYREDMPDKIPARLFIQQLRKKLAFAIITILRMLLVSCIWLVVLPYFTIWTWRLYFSLGASLSRHLSRLQQVKHQLGGGSNYLLYNDTMVNNATQTWIEEYKSRLTLQSFLADCFEGQVITCIVIIVFVAVFLLREWIVQNIPMEAPLNEDDELILDPHPIPAIAQINLQQTDELVQLDHQNMPWQNDIEPSPSPSPVASPSWHNDEEIPSLQIGRSMQNEVLPYTRASSLPPTFSRTSSFHDPNTGDRTFEFQRAASLEPFNNLTIGSRLEDTEIADNPFMPPELFFQGNPPNAPRMRHAEAPIGMRPILEENEHAQVPVPLQPPEPILGNNAENNNNDVNEGNEEEAEEFEGILEAIGMQGSLWSLLQNCTLMGLLIALSLGAAVWMPYLIGMLFIMTEAWDMVRVPLKIARLITDPFVDLLFWVSTDVIGPYIQPLLEGIASSPFYSYLLSLFSIDSTSGSSHISQDTSLPLVDLVAQFIEEMKPEFYSALQRYQALAIRQTAFDRFACIAIGYAVVAFFSCWYLTRSAQHRVATVALGRTAQEALRHQGIIFKVSLFIVIELVLFPIVCGYLLEFSTLPLFKQSTTTSLQGLFSSNPVSSVFLHWFLGTGFMFVFAVLVNFCRDVLRPGVMWFIRDPNDPQFHPIREIIERPALFQLRKIISSAFIYLAVIMIGVGGMIHALDIFTGHAILPLRWNFSYSRIPLSVVPVDIIILQIGIPAVVRYFKPKVLLKKLFISWMKFTCRQLRLSSFMFGQRRADEEGALVYHTWTALLKRAKPARYPQDGTIENIIGYDVSYMWEGQLLRVPRHDSVPVTERRRMLVPVDPITLIPLDETERRLGHPAANGSGDEEVNTTIVYSPPHFKQRLFAFVGFMWLSSSFFLCSIAVLPVLLGRTLFEVILNDEEKQAHDIYSFFIGSFVFLFIGVICYQIYNTIREITSQTTLQAVMDTLWHQAKQWSSWIFRWSFFAISFGLLIPLNLGILVELYSILPLKKVTEEEYSVELATMWVHGFAFMILLHGVVQIIPNNRIRNILNNVFREGIHNMNVKLCITRIVGPFLLFSLAAIGFPSIIAYINLKVIARANPELRFKFMQIVYPAALIGVGSYYLTNFIYKIGARLADNIREDNYLIGRTLHNLDQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NAK4</accession>
    <name>A0A1C7NAK4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Glutamine synthetase</fullName>
            <ecNumber evidence="2">6.3.1.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Glutamate--ammonia ligase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="primary">GLN1_1</name>
        <name evidence="12" type="ORF">A0J61_05817</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-glutamate + NH4(+) + ATP = L-glutamine + ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:16169"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.1.2"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 9 10">Belongs to the glutamine synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.1.2" evidence="2"/>
    <dbReference type="EMBL" id="LUGH01000326">
        <property type="protein sequence ID" value="OBZ86137.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NAK4"/>
    <dbReference type="STRING" id="101091.A0A1C7NAK4"/>
    <dbReference type="InParanoid" id="A0A1C7NAK4"/>
    <dbReference type="OrthoDB" id="1936100at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004356">
        <property type="term" value="F:glutamine synthetase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006542">
        <property type="term" value="P:glutamine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.590.10:FF:000004">
        <property type="entry name" value="Glutamine synthetase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.70">
        <property type="entry name" value="Glutamine synthetase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.590.10">
        <property type="entry name" value="Glutamine synthetase/guanido kinase, catalytic domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036651">
        <property type="entry name" value="Gln_synt_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014746">
        <property type="entry name" value="Gln_synth/guanido_kin_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008146">
        <property type="entry name" value="Gln_synth_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050292">
        <property type="entry name" value="Glutamine_Synthetase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20852">
        <property type="entry name" value="GLUTAMINE SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20852:SF57">
        <property type="entry name" value="GLUTAMINE SYNTHETASE 2 CYTOPLASMIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00120">
        <property type="entry name" value="Gln-synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01230">
        <property type="entry name" value="Gln-synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55931">
        <property type="entry name" value="Glutamine synthetase/guanido kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51987">
        <property type="entry name" value="GS_CATALYTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0436">Ligase</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GS catalytic" evidence="11">
        <location>
            <begin position="90"/>
            <end position="356"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009897"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012937"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00021364"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00030668"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00049436"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01331"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51987"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="OBZ86137.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="356" mass="40309" checksum="A24B00C41D623BA2" modified="2016-11-30" version="1">MDLTTPISSKYSQLKLDHSDAIPIEYVFIDKEGNLRSKAETLHKIPTSIKDIPPLILQDKDPDLLEEQYQPIAMYRDPFRPQQGRLVLCEAPTRQRCLEIMDHYAHLEPWFGMEQEYVLFDPKTNKPWGWPQHGEPEKQGTYYCGVGAGRVFGRDIMEAHYRACLFAGITLCGCNAEVTPSQLEYQVGPCLGVTIGDEMYMARYIMERIAEEFGAAVSLHPKPIPGDWNPTGCHINFSTNEMRSSPDGLLAIDQAVENMSSKHFEHIEVYGQDNELRLTGEYETGHISVFSCGVGNRGASIRIPRRVAVEGKGYMEDRRPAGNIDPYAATTIIMTSSFNYKSPYEQEFFLFSEETA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NAW4</accession>
    <name>A0A1C7NAW4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_05700</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000315">
        <property type="protein sequence ID" value="OBZ86252.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NAW4"/>
    <dbReference type="STRING" id="101091.A0A1C7NAW4"/>
    <dbReference type="InParanoid" id="A0A1C7NAW4"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="207"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="27"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="67"/>
            <end position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ86252.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="241" mass="26292" checksum="BC724CB086AD4916" modified="2016-11-30" version="1">MAAAAAAAQQQQQQQQQQGQVRMPTSMPMQQRFANVLASQAQDSNVNQAQQVSPAMTHAQQPPQPQTQPQSQQPQQQQQQTANALALAAQLAQLGYPIQSLGQLPLNQQANLQRYIAQLQLRNTAAAANGNANNNSNTASNNHTIGLSPQLQQQLQQQMLNSLTPQQQQQLLVQQQQRLQAVQMQQQLQLQQQLQQQQLIQRSASTNTNLNTSNGNNNANTNSHTTSANNSGTANNNTNLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NBQ8</accession>
    <name>A0A1C7NBQ8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_05457</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000294">
        <property type="protein sequence ID" value="OBZ86501.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NBQ8"/>
    <dbReference type="InParanoid" id="A0A1C7NBQ8"/>
    <dbReference type="OrthoDB" id="2285112at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="48"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="325"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="602"/>
            <end position="631"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="102"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="146"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="169"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="207"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="227"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="328"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="611"/>
            <end position="631"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ86501.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="631" mass="71390" checksum="98AF7A235C40DD4A" modified="2016-11-30" version="1">MSSEEVTVSLSRLALAKAIKTPDAGEEQEDWSKSVIFHQAHIDDQMLYSMQHPQQHGNRRTKPGRPTKQPIRYPQNNQRLVAPPMHRARSEEAYIKPPMPVSSLSSQNRSLPKSSAQSAHSVDNRSSMSINKLANHSKQGRRYVPSDEEDNEESEEEESEEEDSEEEVIVPTRTPVPTKTTAPVMSSPLPQKNQPLKKPATRAIQPSDDEESESESEEEESDDEAHGDDKKNVKKDEKDTEETEKLYARRMSTLRQLERGSSLHKKSHSTGSLMMLPPADAFIEPTTSLMDTHAAMENAALNAAPPTPGKLGTIEQWRVTVMEAEDMSQPTSTPLSTASSHSPAETVEDDESLVEEPIVRSLNTSSSHLPAMRSQSSLVPNPRASTMDLEMMYYQQQQQMYNMQMQQAMQLQQAHQMAQIQQYQQAIQMQQQQMYAYNNSTTSLNNINNTSSSNKSSHRKSVSAMDLMMQLEQEKAATRKNNKKKMPDPSKANLNEGLLSHVPKHGQHNINFQQQVRKMQHTMPRASISDYHLQQLQQQQQQQKTRPSSSMNIYNMQHASQSSMLKMPRGGDMSPIPTMSTSTPLNQQQAYFIPQQQPMLMPPQQMPMMDSNRSSQYLSNNSKRQSTMNKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NCJ1</accession>
    <name>A0A1C7NCJ1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Sodium/bile acid cotransporter 7</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_05133</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000270">
        <property type="protein sequence ID" value="OBZ86813.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NCJ1"/>
    <dbReference type="STRING" id="101091.A0A1C7NCJ1"/>
    <dbReference type="InParanoid" id="A0A1C7NCJ1"/>
    <dbReference type="OrthoDB" id="188035at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1530.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038770">
        <property type="entry name" value="Na+/solute_symporter_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016833">
        <property type="entry name" value="Put_Na-Bile_cotransptr"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18640:SF5">
        <property type="entry name" value="SODIUM_BILE ACID COTRANSPORTER 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18640">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 10 MEMBER 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13593">
        <property type="entry name" value="SBF_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="61"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="100"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="131"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="161"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="196"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="248"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="279"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="312"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="424"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="7"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="424"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="442"/>
            <end position="453"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ86813.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="466" mass="51045" checksum="F0F03EAB0856D54E" modified="2016-11-30" version="1">MNESRLKTNPSLASDLTLPNSPSNLNRKQTFSPSVYTEKSATIAGNQDSKSKKIFSSAKRFFWALFLKYWFLLGLAIAIILAIFFPNVARKGGYIRAEYSIKWGAVIIIFLISGLSLRTKILAQTILRVRLHFLIQIINLIIIPFTVFGLVLLFFKLHMNINSLLLVGVVIAASTPTTVSSNVVMTKNANGNEASALMNAALGNVLGIFVSPALVSAFQGPLLSATPEDESAAQAGGSVDFVQVLKQLGVTVLAPLVVGQIIQWFFTEAVAKFKVKCRLSDVSSFMLLTMVWSVFSDAVYSGSFAAVHAKDIAAVAILNFGFYILFSLLCLVLARLPLPRFIKTPSIVKRLRYSREDTVAIMYCGATKTVAMGVPLINVLYQNGDPGTVGVLSTPLLLYHVEQLILGNIEVELLKRWVKRGKVEEPEEEHNLSNDEEAITGGISQSDFTQVASPTEPYRHSHSPMP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NCW2</accession>
    <name>A0A1C7NCW2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">ferroxidase</fullName>
            <ecNumber evidence="3">1.16.3.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">A0J61_05546</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>4 Fe(2+) + O2 + 4 H(+) = 4 Fe(3+) + 2 H2O</text>
            <dbReference type="Rhea" id="RHEA:11148"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
            <dbReference type="ChEBI" id="CHEBI:29034"/>
            <dbReference type="EC" id="1.16.3.1"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the frataxin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.16.3.1" evidence="3"/>
    <dbReference type="EMBL" id="LUGH01000302">
        <property type="protein sequence ID" value="OBZ86406.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NCW2"/>
    <dbReference type="FunCoup" id="A0A1C7NCW2">
        <property type="interactions" value="205"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NCW2"/>
    <dbReference type="InParanoid" id="A0A1C7NCW2"/>
    <dbReference type="OrthoDB" id="1897642at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008199">
        <property type="term" value="F:ferric iron binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008198">
        <property type="term" value="F:ferrous iron binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004322">
        <property type="term" value="F:ferroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034986">
        <property type="term" value="F:iron chaperone activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006879">
        <property type="term" value="P:intracellular iron ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006826">
        <property type="term" value="P:iron ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016226">
        <property type="term" value="P:iron-sulfur cluster assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00503">
        <property type="entry name" value="Frataxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.920.10">
        <property type="entry name" value="Frataxin/CyaY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017789">
        <property type="entry name" value="Frataxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002908">
        <property type="entry name" value="Frataxin/CyaY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036524">
        <property type="entry name" value="Frataxin/CyaY_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020895">
        <property type="entry name" value="Frataxin_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR03421">
        <property type="entry name" value="FeS_CyaY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR03422">
        <property type="entry name" value="mito_frataxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16821">
        <property type="entry name" value="FRATAXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16821:SF2">
        <property type="entry name" value="FRATAXIN, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01491">
        <property type="entry name" value="Frataxin_Cyay"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00904">
        <property type="entry name" value="FRATAXIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM01219">
        <property type="entry name" value="Frataxin_Cyay"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55387">
        <property type="entry name" value="Frataxin/Nqo15-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01344">
        <property type="entry name" value="FRATAXIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50810">
        <property type="entry name" value="FRATAXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0406">Ion transport</keyword>
    <keyword evidence="9" id="KW-0408">Iron</keyword>
    <keyword evidence="4" id="KW-0409">Iron storage</keyword>
    <keyword evidence="6" id="KW-0410">Iron transport</keyword>
    <keyword evidence="11" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008183"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013107"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00047990"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="OBZ86406.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="176" mass="20450" checksum="E0784D154840D547" modified="2016-11-30" version="1">MLRQIVLASARYSKPLLSSRATSRALFYSRQARLTPCLQRSFHFSPALSNSYKATELTTERYHRLSDEVLDHIVGRLEELCDELDLPGFDVEYSQGVMTISVGEHGTYVVNKQPPNHQIWLSSPVSGPQRFDYDEKHQRWFYHRDNHTLEEVLNKELSEALKQPIDLLEGYDPKEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NDZ2</accession>
    <name>A0A1C7NDZ2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Cytoplasmic dynein 1 light intermediate chain 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">Dync1li2</name>
        <name evidence="12" type="ORF">A0J61_04643</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the dynein light intermediate chain family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000231">
        <property type="protein sequence ID" value="OBZ87315.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NDZ2"/>
    <dbReference type="STRING" id="101091.A0A1C7NDZ2"/>
    <dbReference type="InParanoid" id="A0A1C7NDZ2"/>
    <dbReference type="OrthoDB" id="27603at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005868">
        <property type="term" value="C:cytoplasmic dynein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035974">
        <property type="term" value="C:meiotic spindle pole body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045504">
        <property type="term" value="F:dynein heavy chain binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000226">
        <property type="term" value="P:microtubule cytoskeleton organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007018">
        <property type="term" value="P:microtubule-based movement"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008467">
        <property type="entry name" value="Dynein1_light_intermed_chain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022780">
        <property type="entry name" value="Dynein_light_int_chain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12688">
        <property type="entry name" value="DYNEIN LIGHT INTERMEDIATE CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12688:SF0">
        <property type="entry name" value="DYNEIN LIGHT INTERMEDIATE CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05783">
        <property type="entry name" value="DLIC"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="10" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="8" id="KW-0243">Dynein</keyword>
    <keyword evidence="5" id="KW-0493">Microtubule</keyword>
    <keyword evidence="9" id="KW-0505">Motor protein</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="468"/>
            <end position="488"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="500"/>
            <end position="570"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="606"/>
            <end position="640"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="514"/>
            <end position="530"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="535"/>
            <end position="544"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="625"/>
            <end position="634"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006831"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="OBZ87315.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="649" mass="70985" checksum="EE5E7EACEA275671" modified="2016-11-30" version="1">MSDFLLSSVTPSQSVSTNSVMTQQQQSTSIPEKDEIWSSILKSVASTKMVPTKNVLILGEPGVGKSTLVNYLKNDPGPQQLSNFEKEDNTPFSSAPIHLYTPFTEEDTSDLALGYTYVDIKDEENEAMARLGLYQLGLSSPEFFPLLKFAIRAETVADSCVVILLDWTRPWKFLEMLERWISIVQTLIDEICKEGLAMDSNWSRGRAMVDELKEKLEHYLQTYTEPSQLNKDIVMTASTSTSSIPSASASTQFVSNNTQPITSSSTTTTTAIDHNVMLPLPTGCLTTNLGIPITVVCCKSDFINSLEQTYDYQDDQFDYIQQTLRCVCMKYGAALFYTSTLNPYTFHNLREYLLHRTLTTPSKPYPFNLKAQVVERDTVLVPSGWDSWGKIKVLREGFECDLISEGWDTDMDAVFERQNPGHTGARGTYEEAIPNEDESKIQPQHIPVITTCEDEQSFYDRHFEKLQKNSDTTARQGTGGALDKPGVVGPLGVSPATLHLMRGAGNTPSIGIETNERTSRKKDLTLEKLLMKGIGNTSPKSNGHMSPISPPGNASPMTTSPPQSSSSSVAAAAAAAVNNVGTHALPGQNPPSHEVLANFFQSLLKTSSGSTTSTGGGGSPTSASILNGQPNSSRTPKDLDVMREYTASK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NDZ5</accession>
    <name>A0A1C7NDZ5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_05163</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000272">
        <property type="protein sequence ID" value="OBZ86776.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NDZ5"/>
    <dbReference type="InParanoid" id="A0A1C7NDZ5"/>
    <dbReference type="OrthoDB" id="2237583at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ86776.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="103" mass="11891" checksum="B7ED432A57043DEC" modified="2016-11-30" version="1">MPKAKSQKVTKKTPYTRDQNKDKKNAKTKKPLNKSEKLRNADLTESLDDLLGDLQQHLAPKKKKPLTLKNNTMEDTSKIEEEQRLYEKTQNDIDAALNLLDKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-06-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NE66</accession>
    <name>A0A1C7NE66_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_04567</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000226">
        <property type="protein sequence ID" value="OBZ87381.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NE66"/>
    <dbReference type="InParanoid" id="A0A1C7NE66"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ87381.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="164" mass="18947" checksum="C8C6A1500418D62F" modified="2016-11-30" version="1">MMLKSKKHVPKDDIPIQETSALAEKWSHLLTFSPPNPENLYILETFKRSKILRHELATDLSESDANKCEYKEALQDIVGDTPQPMEEHGITVEGDIVEAEQKDVEKDVEKEVLDTDEDKLRGIIGTSLEPQTLEKHKRGRPKNKQSLYQFCQRRKTVFVVYLKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NE78</accession>
    <name>A0A1C7NE78_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_04690</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000235">
        <property type="protein sequence ID" value="OBZ87250.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NE78"/>
    <dbReference type="InParanoid" id="A0A1C7NE78"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="50"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="53"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ87250.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="70" mass="7545" checksum="DF0A2303EF5F26A1" modified="2016-11-30" version="1">MMQHWNRIVSEGITLNVRLNMPESSQQAELTTRSLSSNITVLSVASNPSILQTESSPSIPTSISTTTIAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NEL9</accession>
    <name>A0A1C7NEL9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">thioredoxin-dependent peroxiredoxin</fullName>
            <ecNumber evidence="2">1.11.1.24</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">Prdx1_1</name>
        <name evidence="12" type="ORF">A0J61_04404</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>a hydroperoxide + [thioredoxin]-dithiol = an alcohol + [thioredoxin]-disulfide + H2O</text>
            <dbReference type="Rhea" id="RHEA:62620"/>
            <dbReference type="Rhea" id="RHEA-COMP:10698"/>
            <dbReference type="Rhea" id="RHEA-COMP:10700"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:30879"/>
            <dbReference type="ChEBI" id="CHEBI:35924"/>
            <dbReference type="ChEBI" id="CHEBI:50058"/>
            <dbReference type="EC" id="1.11.1.24"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.11.1.24" evidence="2"/>
    <dbReference type="EMBL" id="LUGH01000215">
        <property type="protein sequence ID" value="OBZ87541.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NEL9"/>
    <dbReference type="FunCoup" id="A0A1C7NEL9">
        <property type="interactions" value="531"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NEL9"/>
    <dbReference type="InParanoid" id="A0A1C7NEL9"/>
    <dbReference type="OrthoDB" id="185659at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008379">
        <property type="term" value="F:thioredoxin peroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045454">
        <property type="term" value="P:cell redox homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033554">
        <property type="term" value="P:cellular response to stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042744">
        <property type="term" value="P:hydrogen peroxide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006979">
        <property type="term" value="P:response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd03015">
        <property type="entry name" value="PRX_Typ2cys"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.30.10:FF:000003">
        <property type="entry name" value="Peroxiredoxin 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000866">
        <property type="entry name" value="AhpC/TSA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050217">
        <property type="entry name" value="Peroxiredoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024706">
        <property type="entry name" value="Peroxiredoxin_AhpC-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019479">
        <property type="entry name" value="Peroxiredoxin_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10681:SF171">
        <property type="entry name" value="PEROXIREDOXIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10681">
        <property type="entry name" value="THIOREDOXIN PEROXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10417">
        <property type="entry name" value="1-cysPrx_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00578">
        <property type="entry name" value="AhpC-TSA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000239">
        <property type="entry name" value="AHPC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 9" id="KW-0049">Antioxidant</keyword>
    <keyword evidence="6" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5 9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3 9" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="7 9" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin" evidence="11">
        <location>
            <begin position="3"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="active site" description="Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity" evidence="10">
        <location>
            <position position="48"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009796"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00049091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRNR" id="PIRNR000239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR000239-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="OBZ87541.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="195" mass="21635" checksum="3B7FEDBE6EC800A1" modified="2016-11-30" version="1">MVAQVQKPAPAFTAPAVVNGEFKDISLSDYKGKYVVFFWYPMDFTFVCPTEILAFSERVKEFEALDTVVIGASTDSEFSHLAWINTPRKQGGLGEMNIPLLADKTKSIAKDYGVLIEEAGVALRGLFIIDPKGIVRQITINDLPVGRSVDEVLRLVEAFQFTDKHGEVCPANWKAGAKTIKPDVEKSKEYFNTVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NFR8</accession>
    <name>A0A1C7NFR8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Translocon-associated protein subunit beta</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_04540</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000225">
        <property type="protein sequence ID" value="OBZ87406.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NFR8"/>
    <dbReference type="InParanoid" id="A0A1C7NFR8"/>
    <dbReference type="OrthoDB" id="2278235at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008889678" description="Translocon-associated protein subunit beta" evidence="1">
        <location>
            <begin position="26"/>
            <end position="172"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ87406.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="172" mass="18683" checksum="AB104E790096CC7E" modified="2016-11-30" version="1">MKVSIKCQTSILIAILSLLLSAVHAQLGPVVLSPEQNATVPAGGKMDIVYQYQNVGNGSYSVDIQLWQDAAATIPISDVVKDQEIKAGNSSGVKVNFYLNTTYSWNVPHGLNKTFWLTVTETAETKLYAKGISLRSRPVMLHTSAAKLHFTPTSMAYLLASSVCLLFIHSLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NFS2</accession>
    <name>A0A1C7NFS2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">NADP-dependent alcohol dehydrogenase C 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">adhC2_0</name>
        <name evidence="7" type="ORF">A0J61_05745</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 5">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the zinc-containing alcohol dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000320">
        <property type="protein sequence ID" value="OBZ86204.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NFS2"/>
    <dbReference type="FunCoup" id="A0A1C7NFS2">
        <property type="interactions" value="328"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NFS2"/>
    <dbReference type="InParanoid" id="A0A1C7NFS2"/>
    <dbReference type="OrthoDB" id="1879366at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016616">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05283">
        <property type="entry name" value="CAD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000022">
        <property type="entry name" value="Cinnamyl alcohol dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002328">
        <property type="entry name" value="ADH_Zn_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047109">
        <property type="entry name" value="CAD-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="ER"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42683">
        <property type="entry name" value="ALDEHYDE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00059">
        <property type="entry name" value="ADH_ZINC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Enoyl reductase (ER)" evidence="6">
        <location>
            <begin position="13"/>
            <end position="346"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU361277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OBZ86204.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="348" mass="38390" checksum="BB3090CBF07CD227" modified="2016-11-30" version="1">MATENDTFTGWAGVSKDEPLQQMQLTLKQWDEDSVEMKITHCGICGSDDYTLKSLWGATNYPCVVGHEIVGVVTRVGKNVTNLKVGDRAGVGAQCGSCHECSSCKDSEENCCYKMSGTYNSKWPNGDKTYGGYADKWRGDYRFAFKVPDSLPSEIAATFFCAGVTTYAPLRRTNVNEKSVVGIMGIGGLGHYGILWAKAMGAKVVGMSSSDSKRDVALELGCHEFVNTSDEKALESYKGQLTHILCTGCGPDFTWEKYLTLLKRKGTFINVNAPSWTFPPLKPMLLIGTQANICGSLIGSPKEIEEMLQFAAEKNVRPWIDVFPMKDVNKVLEDFRAGKPRFRFVLEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NFS7</accession>
    <name>A0A1C7NFS7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="2">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">CST20</name>
        <name evidence="14" type="ORF">A0J61_04032</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="2"/>
    <dbReference type="EMBL" id="LUGH01000188">
        <property type="protein sequence ID" value="OBZ87915.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NFS7"/>
    <dbReference type="STRING" id="101091.A0A1C7NFS7"/>
    <dbReference type="InParanoid" id="A0A1C7NFS7"/>
    <dbReference type="OrthoDB" id="2914378at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050629">
        <property type="entry name" value="STE20/SPS1-PAK"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48012:SF10">
        <property type="entry name" value="FI20177P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48012">
        <property type="entry name" value="STERILE20-LIKE KINASE, ISOFORM B-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 14" id="KW-0418">Kinase</keyword>
    <keyword evidence="5 10 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 11" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="13">
        <location>
            <begin position="201"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="54"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="8"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="231"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008874"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU000304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="OBZ87915.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="479" mass="55026" checksum="BF53018E8C062352" modified="2016-11-30" version="1">MISRRKSSIFNSNDTNHSAVSPTNKFDGKAAINVLKDNRKHMLGGFLSNKRTSLGSLRKSKSSTTADAKSRQAQMTPVNVDMKRRSIGCLRRDSVYSNKSSTEFANHLTTKVWRSPGFYEIPNVFGSDCFLKPEPVSEKTYQLRTFNLQKHISKHPWRPAGFCNEIPQLPPLIRAENGFEKRIRKVLPKISVSSLDPNNKYGALKEIGTGVNGAVVRAQHRYKKNMLLAIKRCRLDPDREYKASIVRELRIMATGHSNLIRLREVSLWKQEVWMAMDLMRCSVFAVLCQRGIPEQYTIHIACEALKGLVYLHSKSFIHRDIKCENILLGWNGEVKLADFGLATKTIRKNRERLGTSKWMAPEVIREQLYDEKIDIWSLGITLIEMMDRVPPHYLIKDETDLFNMILNESSPTFTYSYPTMYMRGLVVWLLDETPSTRPHASQVLQEIEIHVQNKMLQCASSIELARFVNHVFNPNKQLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NG19</accession>
    <name>A0A1C7NG19_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 9">Exportin-T</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Exportin(tRNA)</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">tRNA exportin</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="primary">los1</name>
        <name evidence="13" type="ORF">A0J61_05651</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">tRNA nucleus export receptor which facilitates tRNA translocation across the nuclear pore complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="9">Nucleus</location>
        </subcellularLocation>
        <text evidence="9">Shuttles between the nucleus and the cytoplasm.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the exportin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000311">
        <property type="protein sequence ID" value="OBZ86304.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NG19"/>
    <dbReference type="FunCoup" id="A0A1C7NG19">
        <property type="interactions" value="841"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NG19"/>
    <dbReference type="InParanoid" id="A0A1C7NG19"/>
    <dbReference type="OrthoDB" id="26399at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016363">
        <property type="term" value="C:nuclear matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005643">
        <property type="term" value="C:nuclear pore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031267">
        <property type="term" value="F:small GTPase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071528">
        <property type="term" value="P:tRNA re-export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013598">
        <property type="entry name" value="Exportin-1/Importin-b-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045546">
        <property type="entry name" value="Exportin-T_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001494">
        <property type="entry name" value="Importin-beta_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040017">
        <property type="entry name" value="XPOT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15952:SF11">
        <property type="entry name" value="EXPORTIN-T"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15952">
        <property type="entry name" value="EXPORTIN-T/LOS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19282">
        <property type="entry name" value="Exportin-T"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03810">
        <property type="entry name" value="IBN_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08389">
        <property type="entry name" value="Xpo1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8 9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 9" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4 9" id="KW-0813">Transport</keyword>
    <keyword evidence="6 9" id="KW-0820">tRNA-binding</keyword>
    <feature type="domain" description="Importin N-terminal" evidence="10">
        <location>
            <begin position="37"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="domain" description="Exportin-1/Importin-beta-like" evidence="11">
        <location>
            <begin position="118"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="domain" description="Exportin-T C-terminal" evidence="12">
        <location>
            <begin position="324"/>
            <end position="997"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00018928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU366037"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF03810"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF08389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF19282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="OBZ86304.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="999" mass="113922" checksum="AF64E32B9C1EA441" modified="2016-11-30" version="1">MDQIEQAVMYALGPQVDPNLKAQVFNKCPIELITRNANAYCEQVKNSNEGWQLCIELFMKEPKALPEARFFALQVVENTLRTRFNTLDNAAVEYIQRTMMEYLRREFVDNTSAGSEEAFIRNKAAQLLTLLFIHDMIAIAKTPAGSPSHEKAADFFLRLCISIDEEIARLDIPRTREEVLRNTNIKDTMRLGDIQLLAAFWFDLLQEFRSTNPNIAQLALKNIGSYIAWMDIALVVNDQVMNVLYELLTDANLRISACECLADVISKGMLPLDKLNMLQMLNITSMLGRLDLSEPEFVEYVARLINALGTELCKIFAEPSLPAEGKAQAWTMIEQITPYLLKFLANEYDDTSSAVFPFVNDMLYLFKRQKKQMQPFSQGQHEFLGSLLNVVIVKLRYDNDTEWDTDEDEPEEEALFFEMRKNLRIFAEHIAMINEELYVGYIHSFVMDSINKYRSGVQMDWRDVELCLYVVYCYGEALSKASMIFVTPDNKLSPLGELVSEMICDSLLTHFASLDISAYPHPSCAMQYFENLNRYYQFFDLRPEHLPQALSAFVDGRGLHHAVKQIRTRCWYLFQRFVKNLKPKMGPYVENVLTSIGDLLTIQAEPVVEQNTMDGMPIPAASTFDSQLYLFETVGLLISMDTLDALKQTEYLKIVLQPLVDGIQNSLSQPFNPEDELFLLQVHHYIMAIGSVAKGFPTLEKPSDGTQQPQTVVFVQATEIILSALQAYNQMSVIRDAVRYTFARLITCLGTEIVAYLPNLINGLLTECQVTELVDFLPFIGLVAHKYKPMVEPIIDELLLPLVRRVFDFLNTTPSGTDEALLLLELRKAYLSFILSLFNANLEKVFVSERNLGFLNTILQTFLHFAKDNSDPTTQKMSFGVFLKMVNSWASGADTNTSVAGFDQFVYNELLPITFSVPMSSAFNLADGQSILVFGEMTSIQKAMCVKQGNDFIEYMKKVFFPSIQCPPETAERYCQAIQQYEGRQFKKYFQSFITEAKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NGJ0</accession>
    <name>A0A1C7NGJ0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">A0J61_03821</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000173">
        <property type="protein sequence ID" value="OBZ88138.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NGJ0"/>
    <dbReference type="InParanoid" id="A0A1C7NGJ0"/>
    <dbReference type="OrthoDB" id="2261774at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008889687" evidence="3">
        <location>
            <begin position="20"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="180"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="267"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="279"/>
            <end position="294"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OBZ88138.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="294" mass="33916" checksum="4F15D70056192AA4" modified="2016-11-30" version="1">MYLNKVLFLLLCLSQFTLAAEQHCFDPANCPFYPIHGCFATEDGLVCKDRRIGFEMSIDPFYTFIYKGLDYTIKNDTGLPCHTIPITDELINYVEFRGPEVMNVHDLDLIGNCSSMSYCDKHTKTCQPKMPLGSACRYNMQCYFGIDGIPGHCSNKTCSIRQDIPQYYYNTPRWSMGDQWQAAVIAVLITGGVVISLLVGRVQVKRLAVKVKDLLEKWQNPDDSVQRIPMMVETEEAWNQHHQHPWWKQVPGVNWIYTKLKQKKPQTVDNSGEYYPLHQRTDETTEEPPPYREG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NHF7</accession>
    <name>A0A1C7NHF7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">A0J61_03758</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000169">
        <property type="protein sequence ID" value="OBZ88189.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NHF7"/>
    <dbReference type="STRING" id="101091.A0A1C7NHF7"/>
    <dbReference type="InParanoid" id="A0A1C7NHF7"/>
    <dbReference type="OrthoDB" id="6781668at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00167">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017930">
        <property type="entry name" value="Myb_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001005">
        <property type="entry name" value="SANT/Myb"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00249">
        <property type="entry name" value="Myb_DNA-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00717">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51294">
        <property type="entry name" value="HTH_MYB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50090">
        <property type="entry name" value="MYB_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Myb-like" evidence="2">
        <location>
            <begin position="301"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="domain" description="HTH myb-type" evidence="3">
        <location>
            <begin position="305"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="167"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="435"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="193"/>
            <end position="215"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OBZ88189.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="483" mass="55253" checksum="DCA894A70006C480" modified="2016-11-30" version="1">MVRTKKDAVDSLSKNKNIPIQESTDICAIKSPISPLPCTSDTRADISRHTEFMSNFHMISSTINDHWQAPLVSNLNHLTIDKTKATTMQKLQSLFRNLSAIEISEMLSDCDHNEDEVILRLITHTYYLENIRCRIQQRASAINSGDFQNNFLPKPVHNTSSLVETPTIANSPEEKAADPMSLARPKKVKQSTKKSNPETNIQLKPKSVKNTSSVNAKKDEPVNTNSDVDIGVTNDKPILNRKRSRPNEKAKVRLNLDDALQQIQSSSSRDSFEGWSEARLRAYQMLDTNPNEYYYRFNAPGELQRTGKWNEEEHALFLKRLAEHGANSQWGIFSIAIPGRVGYQCSNYYRQMIKKRQIHDPNYIIDTEGNVHYLFDKKNGKGAIEKTLRIHSKHRSVPILQCLKEKTQAKRKRTIVSDEDEGDDVTYSPKKVVRKKKKLVPRSEVEPHKPLNQHPSSDIEKAAIIGSVNQGRMTRRRYQELRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NHP7</accession>
    <name>A0A1C7NHP7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Pheromone-regulated membrane protein 10</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">A0J61_03299</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ThrE exporter (TC 2.A.79) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000139">
        <property type="protein sequence ID" value="OBZ88662.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NHP7"/>
    <dbReference type="STRING" id="101091.A0A1C7NHP7"/>
    <dbReference type="InParanoid" id="A0A1C7NHP7"/>
    <dbReference type="OrthoDB" id="413008at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010619">
        <property type="entry name" value="ThrE-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051361">
        <property type="entry name" value="ThrE/Ser_Exporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31082">
        <property type="entry name" value="PHEROMONE-REGULATED MEMBRANE PROTEIN 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31082:SF4">
        <property type="entry name" value="PHEROMONE-REGULATED MEMBRANE PROTEIN 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06738">
        <property type="entry name" value="ThrE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="496"/>
            <end position="516"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="523"/>
            <end position="543"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="575"/>
            <end position="591"/>
        </location>
    </feature>
    <feature type="domain" description="Threonine/serine exporter-like N-terminal" evidence="4">
        <location>
            <begin position="390"/>
            <end position="592"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="243"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="339"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="55"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="75"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="88"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="254"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="279"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="592"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00034125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF06738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OBZ88662.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="592" mass="67197" checksum="6462B9AF8A265193" modified="2016-11-30" version="1" fragment="single">MDDNKNQESSTSSSTSRPVRPKLGPKAHSSPRLPVVSITADDDDTGNSPDRQDSLRSSQTDNSLLNIVPMRNRGRRDTYFTDHHRVIEEDETESSESENNDSDTDINEYTEKDEALAYPDDEKDNSTATLNKANSIHSENFRIPNYPAENPEAHSLVEAALIKDEARDRHIRFQDHVVESANLVQRMISQRYTPQQTNSDSLGSFMANRYESRHTEEEPELPSVQASFGSGSVLASLMKLEAHRQGTPEMPQKKEKKKLKIKRNKKPKKAKSLVDFPLSSNNDTFNENSNNGAPKRPSMAYRPVSWLSGTSRSQQRPPMVNRPASWLSEVASNKYVVPSLEKRKKSAPATSRRPSRDSMLTTASQFERITLEDRIRITFEIANILQKQEFLRKLCRALMHYGCPAHRLEYAMRQVSRTLAVDAEYVYFPSIMLITFIDSTTHTTDTHFIRQAQAFEMHRLQDIHRLEKLVAHGEVTVDEALEFIDKVASQPAIYPMWLHPFVYALAAFAGCILFFGGRWKEGGICAALSSEYLNVYFLVFATNEIFSNYIASFQPIWEITVCVVIGFVARAITKYGFCFTPIAFSSFIIVLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NI03</accession>
    <name>A0A1C7NI03_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Glycogen synthase kinase 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">gsk3_3</name>
        <name evidence="13" type="ORF">A0J61_03804</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Protein kinase that acts downstream of the MPS1 MAPK cascade as a highly conservative signal modulator that dictates growth, conidiation and pathogenicity. Phosphorylates HAT1 at 'Ser-8' to block its translocation from the nucleus to the cytoplasm where HAT1 positively regulates appressorium development and pathogenicity.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. GSK-3 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000172">
        <property type="protein sequence ID" value="OBZ88146.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NI03"/>
    <dbReference type="FunCoup" id="A0A1C7NI03">
        <property type="interactions" value="480"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NI03"/>
    <dbReference type="InParanoid" id="A0A1C7NI03"/>
    <dbReference type="OrthoDB" id="272141at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004712">
        <property type="term" value="F:protein serine/threonine/tyrosine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030154">
        <property type="term" value="P:cell differentiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd14137">
        <property type="entry name" value="STKc_GSK3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000009">
        <property type="entry name" value="Glycogen synthase kinase-3 beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000082">
        <property type="entry name" value="Shaggy-related protein kinase kappa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050591">
        <property type="entry name" value="GSK-3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039192">
        <property type="entry name" value="STKc_GSK3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24057">
        <property type="entry name" value="GLYCOGEN SYNTHASE KINASE-3 ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24057:SF0">
        <property type="entry name" value="PROTEIN KINASE SHAGGY-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0309">Germination</keyword>
    <keyword evidence="6 13" id="KW-0418">Kinase</keyword>
    <keyword evidence="5 10 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 11" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="12">
        <location>
            <begin position="42"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="72"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022544"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00055136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00072289"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU000304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="OBZ88146.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="398" mass="45146" checksum="D5FCE28CEEFA14E4" modified="2016-11-30" version="1">MSTSHSNHFKFSGKIGDAFDSLRTIRVPAKDGRNGQDIQLQYSHQKVIGNGSFGVVYQVKLAHSGEDAAIKKVLQDKRFKNRELEIMRLMSHPNVCGIKAYFYSQGDTKKDEVYLNLVMEYVPETVYRVTRHYTKIKQAVPMLIVKLYMYQLFRSLAYSHTLGICHRDIKPQNLLVHPVTGVLKLCDFGSAKILVEGGMNVAYICSRYYRAPELIFGASCYTCSIDIWSAGCVMGELLLGQPLFPGESGIDQLVEIIKVLGTPTKEQILTMNPNYTDHKFPSIKPHPLSKVFRSRTPPEAIDLLSHILQYDPKQRPTASEAMVHPFFDELRNPETKMATGRELPELFNFTQEELSIRPDLIHKLVPPHYADTLEKTTGIDINQFTPIPLSDLRLNSLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NIE6</accession>
    <name>A0A1C7NIE6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Monocarboxylate transporter 12</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">SLC16A12</name>
        <name evidence="5" type="ORF">A0J61_03646</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000161">
        <property type="protein sequence ID" value="OBZ88306.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NIE6"/>
    <dbReference type="STRING" id="101091.A0A1C7NIE6"/>
    <dbReference type="InParanoid" id="A0A1C7NIE6"/>
    <dbReference type="OrthoDB" id="6499973at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd17352">
        <property type="entry name" value="MFS_MCT_SLC16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050327">
        <property type="entry name" value="Proton-linked_MCT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11360:SF284">
        <property type="entry name" value="EG:103B4.3 PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11360">
        <property type="entry name" value="MONOCARBOXYLATE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="43"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="82"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="112"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="137"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="169"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="201"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="246"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="280"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="312"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="337"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="370"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="406"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="4">
        <location>
            <begin position="42"/>
            <end position="435"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OBZ88306.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="435" mass="47057" checksum="097BB4D2187DA35F" modified="2016-11-30" version="1">MTIEGNVSNDSTVKSVSISNEYDAKSTHSDTASAITPPDGGRGWLVVAGSFLGMFSIFGYNYSWGVYLNLYKSQVYVGQMSTLSWIGSICVALFFITGPINQFVIEKMGFKYMLMTGTVLCTAALILASFATQVWQIFLTQGVLFGLGASFVSLPCIGAPQQWFSTKRGLAIGLAMSGSGIGGLVVANISMAVIKSLGYRWALRVDGIIVFVLLSISSFLVRPFGDVRKTGGGRKLFNWYLFKNPMFVAMFLHGLITTFGYMTPFFLLPSHANALQLDPWVGTNLSAIMSAVNAVARVFTGYMGDKLGRFNSLFLCTFFCGVCCLVIWINVHNEATLWVFAVLYGFFGGGYVALFPTVQPQIVGLEHIGPAIGLLYTTNIFGYLFGTPIASALINLSSPPSYVNGAIWAGVTIIVGSLFAGWVRVLKGGWTLARI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NII8</accession>
    <name>A0A1C7NII8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_03029</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000124">
        <property type="protein sequence ID" value="OBZ88921.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NII8"/>
    <dbReference type="InParanoid" id="A0A1C7NII8"/>
    <dbReference type="OrthoDB" id="2138242at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="117"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="269"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="124"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="149"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="274"/>
            <end position="288"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ88921.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="308" mass="34748" checksum="1008E5D2D60DD306" modified="2016-11-30" version="1">MTHQQDDIEDEESNMLTLPKPSSLLLKRLAPKHGHAKNLTILTSSYNNDIAHSIQSAPLKRSTAHPLQIPPNKLLNKVVKRSPPTASLKSNMRRLVVPATASAVSAPWPHTSVQARFPSPPIVPSQQPTWGQYNKTPGNTLKSARLLQSHTNTPNTTNTTHSNTRHHTHSASPPRSYPSTNTATQKQKFLQPFEFLYDHIEQTRALKSTLDDQIRRSSSLIQTLQSSSTMVESVARKQVRDTVEYQFEARLRECVDRISRLEYRALSKDRPISPSVSPSPTNKEQDTLTQLMNRIDQLESRLTYQKAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NJN2</accession>
    <name>A0A1C7NJN2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Papain inhibitor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">pi_2</name>
        <name evidence="5" type="ORF">A0J61_02586</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000099">
        <property type="protein sequence ID" value="OBZ89372.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NJN2"/>
    <dbReference type="STRING" id="101091.A0A1C7NJN2"/>
    <dbReference type="InParanoid" id="A0A1C7NJN2"/>
    <dbReference type="OrthoDB" id="623670at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd22191">
        <property type="entry name" value="DPBB_RlpA_EXP_N-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.40.10">
        <property type="entry name" value="RlpA-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051477">
        <property type="entry name" value="Expansin_CellWall"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009009">
        <property type="entry name" value="RlpA-like_DPBB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036908">
        <property type="entry name" value="RlpA-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31836">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31836:SF28">
        <property type="entry name" value="SRCR DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03330">
        <property type="entry name" value="DPBB_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50685">
        <property type="entry name" value="Barwin-like endoglucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008889735" evidence="3">
        <location>
            <begin position="24"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="domain" description="RlpA-like protein double-psi beta-barrel" evidence="4">
        <location>
            <begin position="187"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="125"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="130"/>
            <end position="174"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF03330"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OBZ89372.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="283" mass="31219" checksum="8F9A239E3F0BCF12" modified="2016-11-30" version="1">MQISRTSMLIALLAMFGNAAVLAGQTKCQLSVEKATIRASHSHLRIRGDIDVGNKKCKPTSSGHVKTTVKFNSKKNIQFKDANDKIHSGNECSIVASWYNRPDDYKNSGKNTQIYVPLRSIESIDCNGHSKSHHKTKKSHHKNKKNKTKKSKTKTKKRTTKKKTTKKTTKKTTKKSSGGSYNSHYSGKATFFTPNQGACGDWNDDNDYIAAIGGSLYGSYSRKSSYCGKKVKVVNKSNGKSVTVTIKDACESCAKTHIDLSPAAFAQIGKFDTGVLSVDWYIY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NJZ6</accession>
    <name>A0A1C7NJZ6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 10">Vacuolar protein sorting-associated protein 27</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">vps27_1</name>
        <name evidence="14" type="ORF">A0J61_02827</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Component of the ESCRT-0 complex which is the sorting receptor for ubiquitinated cargo proteins at the multivesicular body (MVB) and recruits ESCRT-I to the MVB outer membrane.</text>
    </comment>
    <comment type="subunit">
        <text evidence="10">Component of the ESCRT-0 complex composed of HSE1 and VPS27.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 10">Endosome membrane</location>
            <topology evidence="1 10">Peripheral membrane protein</topology>
            <orientation evidence="1 10">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the VPS27 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000112">
        <property type="protein sequence ID" value="OBZ89119.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NJZ6"/>
    <dbReference type="FunCoup" id="A0A1C7NJZ6">
        <property type="interactions" value="124"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NJZ6"/>
    <dbReference type="InParanoid" id="A0A1C7NJZ6"/>
    <dbReference type="OrthoDB" id="957735at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010008">
        <property type="term" value="C:endosome membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033565">
        <property type="term" value="C:ESCRT-0 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032266">
        <property type="term" value="F:phosphatidylinositol-3-phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043130">
        <property type="term" value="F:ubiquitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006623">
        <property type="term" value="P:protein targeting to vacuole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043328">
        <property type="term" value="P:protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd16979">
        <property type="entry name" value="VHS_Vps27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.1940">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008942">
        <property type="entry name" value="ENTH_VHS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017073">
        <property type="entry name" value="HGS/VPS27"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003903">
        <property type="entry name" value="UIM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002014">
        <property type="entry name" value="VHS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000306">
        <property type="entry name" value="Znf_FYVE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017455">
        <property type="entry name" value="Znf_FYVE-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47794">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47794:SF1">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01363">
        <property type="entry name" value="FYVE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02809">
        <property type="entry name" value="UIM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00790">
        <property type="entry name" value="VHS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036956">
        <property type="entry name" value="Hrs_Vps27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00064">
        <property type="entry name" value="FYVE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00726">
        <property type="entry name" value="UIM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00288">
        <property type="entry name" value="VHS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48464">
        <property type="entry name" value="ENTH/VHS domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50330">
        <property type="entry name" value="UIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50179">
        <property type="entry name" value="VHS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50178">
        <property type="entry name" value="ZF_FYVE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 10" id="KW-0967">Endosome</keyword>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="8" id="KW-0862">Zinc</keyword>
    <keyword evidence="7 11" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="VHS" evidence="13">
        <location>
            <begin position="29"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="domain" description="FYVE-type" evidence="12">
        <location>
            <begin position="173"/>
            <end position="233"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008597"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00017753"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022753"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRNR" id="PIRNR036956"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50178"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="OBZ89119.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="561" mass="62380" checksum="4144810A1C508891" modified="2016-11-30" version="1">MSSFWWGPTAFDELVEKATSELLPAGQVDLALHLEISDQIRSKQVNAKESMRSLKRRLLHTNPNVVLATLSGKKQLVDTCVKNSGNAFVKEVATREFMEEMTCLLKTPAECNQDVKAKILELVQVWGIASKGNNELSYLSGTYSLLKAEGYTFPSVTEKIDAILLEAAAPPDWTDSDCCERCRTTFTLTTRKHHCRHCGGTFCQQCSSKNLPLSHIGINNSVRVCDGCYIKVKLSKVADKEAVPHLLKTPASVSSSLAPTYTPSVKSKQINDPVINTQDESNAEDTFENDIKKAIELSLKENQVVQKAEPVVQRKTAEEEEKEEEAALAAAIAASLQDMEAQVPRRNHNELSDADIENIQLFSTLMQHIYSSGNGISGHDEVDTLYTQIGALQPKLIKSLDEASRKHVLFVEMHSKLIAAIKAYDNLLETKLSASRHPSYNTAPYSAQNNYQIQTLPARQSYVSYPTLPNRTSSEVQLGTASSETPIPYYQPAATLRTPAVSHYQPLPSTPSYQLQPQPPQQLHQLYQPHQMQGPIDNQYPSNQQTTYHKQQAEEALLIDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NKD1</accession>
    <name>A0A1C7NKD1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_02355</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000087">
        <property type="protein sequence ID" value="OBZ89603.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NKD1"/>
    <dbReference type="STRING" id="101091.A0A1C7NKD1"/>
    <dbReference type="InParanoid" id="A0A1C7NKD1"/>
    <dbReference type="OrthoDB" id="2281895at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012881810" evidence="2">
        <location>
            <begin position="16"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="109"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="164"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="198"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="251"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="303"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="329"/>
            <end position="354"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ89603.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="373" mass="41107" checksum="E875031DD117924C" modified="2016-11-30" version="1">MKALLSFLIGASVVAYSTYDMLGSADPWASKLLDICFDHDNKEKLGANRVVYTSVFSLLDRTICFYNNFNQSALHDILGAPLSRLMIGAFGTAYALMAFEGSRFGFKHTLLMAFPIFGLLANLFGMYAVFNLMWIPLCIHYQNKAHQQAPSRKSSTWVISLPEAYGILLAIVLGYFVPGAILASPLVPEDSRLEQELLAIWLVLPIIIVPAISFCQTLFRKLGSPVDAVADAALKERLYAAEGKDALERSYLFLGILNMILYFGTYLTVAHQGIRVWDSLMLLLDAPKSLPAGIPFEDLGKLLATRTVLVDLLVLAVGFIFWATLQSGFIVGAVVALITPIVGPAAAISFYSYYREDTLESFVNKSTDEDKNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NKV0</accession>
    <name>A0A1C7NKV0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Williams-Beuren syndrome chromosomal region 16 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">WBSCR16</name>
        <name evidence="4" type="ORF">A0J61_02324</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000086">
        <property type="protein sequence ID" value="OBZ89618.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NKV0"/>
    <dbReference type="STRING" id="101091.A0A1C7NKV0"/>
    <dbReference type="InParanoid" id="A0A1C7NKV0"/>
    <dbReference type="OrthoDB" id="5370059at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.30">
        <property type="entry name" value="Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058923">
        <property type="entry name" value="RCC1-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009091">
        <property type="entry name" value="RCC1/BLIP-II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000408">
        <property type="entry name" value="Reg_chr_condens"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051210">
        <property type="entry name" value="Ub_ligase/GEF_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22870:SF408">
        <property type="entry name" value="OS09G0560450 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22870">
        <property type="entry name" value="REGULATOR OF CHROMOSOME CONDENSATION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00415">
        <property type="entry name" value="RCC1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25390">
        <property type="entry name" value="WD40_RLD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00633">
        <property type="entry name" value="RCCNDNSATION"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50985">
        <property type="entry name" value="RCC1/BLIP-II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50012">
        <property type="entry name" value="RCC1_3"/>
        <property type="match status" value="5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="RCC1-like" evidence="3">
        <location>
            <begin position="21"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="repeat" description="RCC1" evidence="2">
        <location>
            <begin position="79"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="repeat" description="RCC1" evidence="2">
        <location>
            <begin position="130"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="repeat" description="RCC1" evidence="2">
        <location>
            <begin position="190"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="repeat" description="RCC1" evidence="2">
        <location>
            <begin position="239"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="repeat" description="RCC1" evidence="2">
        <location>
            <begin position="337"/>
            <end position="388"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF25390"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OBZ89618.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="389" mass="42435" checksum="818A4365FD3CD913" modified="2016-11-30" version="1">MLRYNKRAFHTTRQLSATKTVLYGWGQTTALPLTEGHMDRIFHSPVCLKSQKDYALPRDQHITHVATGWGHSLIGTELNQVYAFGLNQSGQLGTLGVGYQVLANEQEKLKLLACGREHSHMVTENEDATTQLYSFGNNMYGQLGLGRNKNTHAGQLVAEQIPRLVSLDKQEIIQQIQCGLDSTLFSTENGSIYGMGWSADGQLGQGKDDQTKPSRLALSAPIKKLSSSTDFTLALSQDGRLWTWGNSEYGQGAQGKVIDRILEPCLVDFPNVIDVAAGGPFSVFLTKGGNVYTCGYGALGLGNNAIQTLEPKEIKELKEIKKIYAATDYAAAITASGELYTWGLNGPTSGRLGLGHEDHAFVPQRVKIDKRVIDVSLGTYHAIAICDDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NKW1</accession>
    <name>A0A1C7NKW1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">7,8-dihydro-8-oxoguanine triphosphatase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">Nudt1</name>
        <name evidence="7" type="ORF">A0J61_03998</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="3">Monomer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the Nudix hydrolase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000186">
        <property type="protein sequence ID" value="OBZ87944.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NKW1"/>
    <dbReference type="STRING" id="101091.A0A1C7NKW1"/>
    <dbReference type="InParanoid" id="A0A1C7NKW1"/>
    <dbReference type="OrthoDB" id="447842at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008413">
        <property type="term" value="F:8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042262">
        <property type="term" value="P:DNA protection"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03427">
        <property type="entry name" value="NUDIX_MTH1_Nudt1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.79.10">
        <property type="entry name" value="Nucleoside Triphosphate Pyrophosphohydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003563">
        <property type="entry name" value="8ODP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015797">
        <property type="entry name" value="NUDIX_hydrolase-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43758">
        <property type="entry name" value="7,8-DIHYDRO-8-OXOGUANINE TRIPHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43758:SF2">
        <property type="entry name" value="OXIDIZED PURINE NUCLEOSIDE TRIPHOSPHATE HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01403">
        <property type="entry name" value="8OXTPHPHTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55811">
        <property type="entry name" value="Nudix"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005582"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OBZ87944.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="118" mass="13921" checksum="C412623FB89ED961" modified="2016-11-30" version="1">MEESEIEALDLQKQGLLLFTFEGDPVALETHIFVVKKYQGQPKETEEMKPEWFALDAIPFDKMWSDDKFWFPFLLSHQSFTGHFHFAKDQKTIIKNNLKEVKQLSEGFDLDHAWQSLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NLU3</accession>
    <name>A0A1C7NLU3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_01853</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000064">
        <property type="protein sequence ID" value="OBZ90082.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NLU3"/>
    <dbReference type="InParanoid" id="A0A1C7NLU3"/>
    <dbReference type="OrthoDB" id="10331130at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008889775" evidence="1">
        <location>
            <begin position="21"/>
            <end position="115"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ90082.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="115" mass="13074" checksum="620FE4C0A1A6585F" modified="2016-11-30" version="1">MVYLRYLALTALTAVLNVQASVISDYSSEYFSERVSERVSQYVSEYALPTNLPVDGYYNAPADFPCKIMPTCYTRNTVFIQDPCRAQYGNGWGNVATIACLTNFNEEQYVCCRFQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NM16</accession>
    <name>A0A1C7NM16_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Cyclin-dependent kinase 8</fullName>
            <ecNumber evidence="4">2.7.11.22</ecNumber>
            <ecNumber evidence="3">2.7.11.23</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="19" type="primary">SSN3</name>
        <name evidence="19" type="ORF">A0J61_01876</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="19 20" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19 20">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="15">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.22"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.22"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="16">
            <text>[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:10216"/>
            <dbReference type="Rhea" id="RHEA-COMP:11321"/>
            <dbReference type="Rhea" id="RHEA-COMP:11322"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43176"/>
            <dbReference type="ChEBI" id="CHEBI:68546"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.23"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="19">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.22" evidence="4"/>
    <dbReference type="EC" id="2.7.11.23" evidence="3"/>
    <dbReference type="EMBL" id="LUGH01000065">
        <property type="protein sequence ID" value="OBZ90078.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NM16"/>
    <dbReference type="FunCoup" id="A0A1C7NM16">
        <property type="interactions" value="975"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NM16"/>
    <dbReference type="InParanoid" id="A0A1C7NM16"/>
    <dbReference type="OrthoDB" id="6284126at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990508">
        <property type="term" value="C:CKM complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016592">
        <property type="term" value="C:mediator complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004693">
        <property type="term" value="F:cyclin-dependent protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008353">
        <property type="term" value="F:RNA polymerase II CTD heptapeptide repeat kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0060258">
        <property type="term" value="P:negative regulation of filamentous growth"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000122">
        <property type="term" value="P:negative regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070481">
        <property type="term" value="P:nuclear-transcribed mRNA catabolic process, non-stop decay"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031648">
        <property type="term" value="P:protein destabilization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd07842">
        <property type="entry name" value="STKc_CDK8_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000408">
        <property type="entry name" value="Serine/threonine-protein kinase SSN3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050108">
        <property type="entry name" value="CDK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24056">
        <property type="entry name" value="CELL DIVISION PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24056:SF495">
        <property type="entry name" value="CYCLIN-DEPENDENT KINASE 8-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10 19" id="KW-0418">Kinase</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-0539">Nucleus</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0678">Repressor</keyword>
    <keyword evidence="6" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="18">
        <location>
            <begin position="19"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="350"/>
            <end position="380"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00041823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00047811"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00048367"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00049280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="OBZ90078.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="380" mass="44046" checksum="C8E69FD20227FBB1" modified="2016-11-30" version="1">MTEYKQRRDARRPKVHDKYEIIGFISSGTYGRVYKARSRSKDDRREFAIKKFKPDREGDTHHYVGISQSACREIAVIALEEVLLEDKAIYMVFEYTEHDFLQIIHYHLHTERKPIQDVVIKSFLWQLINGVAYLHSNWVLHRDLKPANVLLTSEGVVKTADLGLARLFNKPLQPLFNGDKVVVTIWYRAPELLFGSRHYTKAIDMWAVGCIFGELLALKPIFKGEEAKMDGKKNVPFQRSQLSKIFEIMGTPTKEKWPAIDQLPDYPHLSSFPQCANRLKQVYNDMPCNKTEAGFNLLSSLLEYDPLRRITAEKALNHPYFQEDPKPVMNVLAQHNIEYPLRRITQEDNDIKSSKAVASQAQQFNKEDHSSRMAKKPRNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NM28</accession>
    <name>A0A1C7NM28_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Periplasmic binding protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_01905</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000066">
        <property type="protein sequence ID" value="OBZ90050.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NM28"/>
    <dbReference type="STRING" id="101091.A0A1C7NM28"/>
    <dbReference type="InParanoid" id="A0A1C7NM28"/>
    <dbReference type="OrthoDB" id="409848at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38360:SF1">
        <property type="entry name" value="F12P19.7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38360">
        <property type="entry name" value="OS03G0120000 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008889779" description="Periplasmic binding protein" evidence="2">
        <location>
            <begin position="21"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="421"/>
            <end position="442"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ90050.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="464" mass="52026" checksum="374073007B4594B0" modified="2016-11-30" version="1">MNLLLKLIVAFTLFSQDVFTQNSTGFDKTVDRYNFKTTMTNVSLSGFTIEYKNYYKVVTNTITSKSYCLVGFEQPIPEGCHSETTVSIPVKSFSVDSDAYGVIPFIELLDLQKNITKTATTNITSPCIANGSRDTNITSPDMIFSFSTSYGATYVDFSANQDTLLPLQKASWLLYIGAFFDLELKSSAVYNQIVNNYNCHKDNLARLGYSPKGVAWTTFESSDSLFTLHSDVYYHQLTMDANAHLVATNMAQPDVFQVNITIQQMNLATALRGADYILDTSQTSLMFDNWIRAGQSYFAAGNPYIEIPAINQHKVYTVNRLINANQVSDWTQRSAARPDLALLDLIKLVYPDFSVPSNDLFPIWLTPYNQVNETRQVLTTDGYGGCQDISMRAFEQSECVLGASVGSTFIERPHLTEGGKAGISVGSIALFFIGVALALWAYRRYRRRQHSYLSNHGFYKLEEM</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NM47</accession>
    <name>A0A1C7NM47_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Tip elongation aberrant protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">tea1_0</name>
        <name evidence="8" type="ORF">A0J61_01755</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000059">
        <property type="protein sequence ID" value="OBZ90202.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NM47"/>
    <dbReference type="FunCoup" id="A0A1C7NM47">
        <property type="interactions" value="13"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NM47"/>
    <dbReference type="InParanoid" id="A0A1C7NM47"/>
    <dbReference type="OrthoDB" id="45365at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="FunFam" id="2.120.10.80:FF:000049">
        <property type="entry name" value="Cell polarity protein (Tea1)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.80">
        <property type="entry name" value="Kelch-type beta propeller"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015915">
        <property type="entry name" value="Kelch-typ_b-propeller"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006652">
        <property type="entry name" value="Kelch_1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46093">
        <property type="entry name" value="ACYL-COA-BINDING DOMAIN-CONTAINING PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46093:SF18">
        <property type="entry name" value="FIBRONECTIN TYPE-III DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24681">
        <property type="entry name" value="Kelch_KLHDC2_KLHL20_DRC7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00612">
        <property type="entry name" value="Kelch"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117281">
        <property type="entry name" value="Kelch motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2" id="KW-0880">Kelch repeat</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="341"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="482"/>
            <end position="529"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="544"/>
            <end position="577"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="771"/>
            <end position="798"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="922"/>
            <end position="942"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="851"/>
            <end position="920"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="341"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="363"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="396"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="486"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="498"/>
            <end position="508"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="551"/>
            <end position="562"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="773"/>
            <end position="798"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OBZ90202.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="942" mass="104654" checksum="E9F0B8FC2808F7C5" modified="2016-11-30" version="1">MSLFSKLAKGNDKTLYPWSQKKLGGSNHCLPRSAHAATVVQPDAIVIFGGVHKASQKKELFYIDTNNNSANSISTTGDIPAARVAPIMVTLNGQVILYGGRPLVPEEKYDGSIYVLNLHAKQWTRIQPEGPQPSERSGHSVATQDNAMFIFGGQKEGHYFNDLYVFNSDTLSTGPRWEQLTFNNKAGDCPEPRSGHVSVIFDNKLYIFGGTDGQHMLNDLWAFDLHSRVWARVESEGLMPAARESSGCAMVDGVMYIFGGRGEHGAELNDLCAFRMRTRRWFRFQNMGPSPSPRHGLTMTAIRERLFVVGGENDISKMDDSSSLYILDSSKIKYPTDTLLTQQSTESTQPTQSAEPMIEDQHSQPSPVQHQQVYPQKPFTDPRQQQPSRPYPPQNAPQGQNSIQVSIPPVRPPRHISTVPEAVLRRPRATSPLLQNDSEIVVDARRPYPSNVSPTSPVSIENELMRASPIQTNIMAATDEAMDPNQQQRSFQQALAQNSIRASPVNASTPPPRPPREGVGLGNTSRTATPDLVRNQSIPAAQLQPSQLEGSHSNPSHSPEPSYAIPERSPSRTAAPVATAATAASVMRPQPDTGAAAVAAAAAAAAAAEERQMLLREIQSRDNIINEMKQKENWWRTEVSLARKQQASRGEGFDGPEADESLLMDVDHLPEDKVKLFEQLISVKSELRRVKTSILQQAQPMSDKVHQADRMRTAALQEAAYFKSKYLALKSRRQQDLGQIEISRCDELEKRLALALSENEANAKMLQQLQKRSQHDQVARTATEERAREAQERAEEAQDAHQRALEELQVVYARATKAELQVRDNAMKIADLTQQLSEALLSQPAVISQDVTEAQMKASQLEAANLRARNETASLKQKLADQMDDIDRLRTALNEREDALAEARRHVEDYEIQLNMMRDAMNQQPNTNTTNTINGYAPTRAY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NMF1</accession>
    <name>A0A1C7NMF1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_02311</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000085">
        <property type="protein sequence ID" value="OBZ89636.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NMF1"/>
    <dbReference type="STRING" id="101091.A0A1C7NMF1"/>
    <dbReference type="InParanoid" id="A0A1C7NMF1"/>
    <dbReference type="OrthoDB" id="2289918at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="156"/>
            <end position="194"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ89636.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="340" mass="38456" checksum="66FA239E49DA0D0C" modified="2016-11-30" version="1">MYNQFASPNMILSPIMNKRKSYSVLENDEPALETNRLMHGSGNKKARHEASWTLDNLCTHPCSPLATVELESIFNMPTFQLVSQREEPYLFLPDIDQNSLLNHSFETDSYYHNDCYGAYNQAIYPPPSFFSKTENPMVWNSLTEWQTMLGQAEFLDQPDSPPLPLSPSPVNHLSSQSSSPYHHKAKSSKSSACSYSSNKKEEHFDAYWSDLADKERAHNVAGDSKSITLKDMCRKGLIREQDVIVYKRNFSACKVIVSKSMTVIKACGLSGISIQLDEEIFEDFETPTALETKILDHHGKVTKDKRPNGNAFKSIRLIRAGKDLGRLFDIRKDGFGDPLC</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NN06</accession>
    <name>A0A1C7NN06_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">D-xylose 1-dehydrogenase (NADP(+), D-xylono-1,5-lactone-forming)</fullName>
            <ecNumber evidence="3">1.1.1.179</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">D-xylose-NADP dehydrogenase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">dhdh</name>
        <name evidence="8" type="ORF">A0J61_01603</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>D-xylose + NADP(+) = D-xylono-1,5-lactone + NADPH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:22000"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15867"/>
            <dbReference type="ChEBI" id="CHEBI:53455"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.1.1.179"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the Gfo/Idh/MocA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.179" evidence="3"/>
    <dbReference type="EMBL" id="LUGH01000053">
        <property type="protein sequence ID" value="OBZ90350.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NN06"/>
    <dbReference type="FunCoup" id="A0A1C7NN06">
        <property type="interactions" value="3"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NN06"/>
    <dbReference type="InParanoid" id="A0A1C7NN06"/>
    <dbReference type="OrthoDB" id="2129491at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047837">
        <property type="term" value="F:D-xylose 1-dehydrogenase (NADP+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.360.10">
        <property type="entry name" value="Dihydrodipicolinate Reductase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000683">
        <property type="entry name" value="Gfo/Idh/MocA-like_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050984">
        <property type="entry name" value="Gfo/Idh/MocA_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055170">
        <property type="entry name" value="GFO_IDH_MocA-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22604">
        <property type="entry name" value="OXIDOREDUCTASES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22604:SF105">
        <property type="entry name" value="TRANS-1,2-DIHYDROBENZENE-1,2-DIOL DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01408">
        <property type="entry name" value="GFO_IDH_MocA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22725">
        <property type="entry name" value="GFO_IDH_MocA_C3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55347">
        <property type="entry name" value="Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Gfo/Idh/MocA-like oxidoreductase N-terminal" evidence="6">
        <location>
            <begin position="2"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="domain" description="GFO/IDH/MocA-like oxidoreductase" evidence="7">
        <location>
            <begin position="131"/>
            <end position="247"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00038984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00042988"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00049233"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF22725"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OBZ90350.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="337" mass="37292" checksum="692B5E51D92D438E" modified="2016-11-30" version="1">MLKWGILGTGSIAHTFAKSLEITDKGQLVAVGSRSLKTAKKFAESFQVPYSFGSYEALLANDQVDIVYIATPHPQHYELALLAARSGKHMLIEKPMAMCTQQVETILKTAKECNVFVMEAYMYKCHPQTKQLVDMIHSGAIGQVKVIRAQFSFDGRSLGPSSRLWLNQLGGGAILDIGGYPMSFARLVAGTNPIKIKATGHVQPETQVDEWSNACLEFEGHITAQLFAGIFADADSSVEVLGSEGVLKVDNLWRPDLTQLGPVQIEWTTYGKSMQVVPVVLEQTDLYVYEIESVTKAILEGKLECHDMSWEDSLGQVRAMDAWRHEIGLYYAEDKKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NN15</accession>
    <name>A0A1C7NN15_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Ribosomal protein L15</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">RPL15B_1</name>
        <name evidence="6" type="ORF">A0J61_01484</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the eukaryotic ribosomal protein eL15 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000047">
        <property type="protein sequence ID" value="OBZ90475.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NN15"/>
    <dbReference type="FunCoup" id="A0A1C7NN15">
        <property type="interactions" value="653"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NN15"/>
    <dbReference type="InParanoid" id="A0A1C7NN15"/>
    <dbReference type="OrthoDB" id="10255148at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022625">
        <property type="term" value="C:cytosolic large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002181">
        <property type="term" value="P:cytoplasmic translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.1120.10:FF:000001">
        <property type="entry name" value="Ribosomal protein L15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1120.10">
        <property type="entry name" value="Ribosomal protein l15e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024794">
        <property type="entry name" value="Rbsml_eL15_core_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000439">
        <property type="entry name" value="Ribosomal_eL15"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020925">
        <property type="entry name" value="Ribosomal_eL15_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012678">
        <property type="entry name" value="Ribosomal_uL23/eL15/eS24_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003269">
        <property type="entry name" value="PRK04243.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11847:SF4">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN EL15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11847">
        <property type="entry name" value="RIBOSOMAL PROTEIN L15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00827">
        <property type="entry name" value="Ribosomal_L15e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01384">
        <property type="entry name" value="Ribosomal_L15e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54189">
        <property type="entry name" value="Ribosomal proteins S24e, L23 and L15e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01194">
        <property type="entry name" value="RIBOSOMAL_L15E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 6" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="166"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="169"/>
            <end position="204"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000663"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OBZ90475.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="204" mass="24108" checksum="BF46464E93ED9CA1" modified="2016-11-30" version="1">MGAYKYLEELSRKKQSDVSRFLLRVRCWEYRQLNVIHRASRPSRPDKARRLGYKAKQGFVIYRIRVRRGGRKRPVPKGATYGKPVNEGVSQLKYQRSLRSTAEERVGRKCANLRVLNSYWINQDATYKYFEVILVDPSHKAIRRDARINWIANPVHKRREARGLTAVGKKSRGHNKGHRFNNTKGSGRRATWKRRNTLSLRRYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NN53</accession>
    <name>A0A1C7NN53_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Amyloid beta A4 protein-binding family B member 1-interacting protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">APBB1IP</name>
        <name evidence="5" type="ORF">A0J61_01375</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000043">
        <property type="protein sequence ID" value="OBZ90572.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NN53"/>
    <dbReference type="STRING" id="101091.A0A1C7NN53"/>
    <dbReference type="InParanoid" id="A0A1C7NN53"/>
    <dbReference type="OrthoDB" id="43122at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001849">
        <property type="entry name" value="PH_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000159">
        <property type="entry name" value="RA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38700:SF1">
        <property type="entry name" value="PH DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38700">
        <property type="entry name" value="YALI0E22418P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00169">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00788">
        <property type="entry name" value="RA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00233">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50003">
        <property type="entry name" value="PH_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50200">
        <property type="entry name" value="RA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ras-associating" evidence="4">
        <location>
            <begin position="142"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="domain" description="PH" evidence="3">
        <location>
            <begin position="243"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="374"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="509"/>
            <end position="602"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="465"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="388"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="399"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="411"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="428"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="546"/>
            <end position="563"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="571"/>
            <end position="596"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50200"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OBZ90572.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="633" mass="71867" checksum="FFF8A0C4C6559D11" modified="2016-11-30" version="1">MEEHQVASEHITIDKRYYSKNSQDNVPLQHYKATRAPHYDSRDDDVCIGTILQRSVTARRPNDEKLPALTHSRSLKVASSRSKQAKEEFHEDEELRLAMQRAWALLDANPEKVSGTTVESTTDGQDTSNMVSSARIQTVPLKTLTTRIYIDDANNHKVVQLTNLLTTAMVVQYLRKKGLLESSDDWTLFEIDNSHGVERPLREWEIVLNTLSVWEPDASNALLIKKYPYHHTLTPESVLQPKIAPMHGWLYIEYKKGKWQKRYCFVKDNAIYHAKDNNKSTSSSVLCYLANYDVYTLLHPSKSSPASFVFAIRAQNRPSIFENESDYIRLLALESQEEMKDWVLSIRNMKSLIQYQQNPARVVNPLTPIALENTFEEKPNTLRRHKSTKESSHKEDYNSTKPPSSGSNHSESVRRSDDKRPLGRSATLRGTSRNNSSANEKDGSENGPLIDCFDTPTFAKGSLLAKEEEQEQVLYRQQQQELQRQQEEASSNANKTLIQVEDRVTFSKGSLLDKKENSSPTVTKMTRSKSVREVSSTPPITEPSEHRRHVSLRRKPTSSRRHHDVPLPNNAAIASLPSTPSSASSNQSPKPSSKAALLQLGDTPESFHTKELYGRHMKPLISFGSSEKFSKKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NNG9</accession>
    <name>A0A1C7NNG9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Abhydrolase domain-containing protein C22H12.03</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">A0J61_01255</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the AB hydrolase superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000038">
        <property type="protein sequence ID" value="OBZ90682.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NNG9"/>
    <dbReference type="FunCoup" id="A0A1C7NNG9">
        <property type="interactions" value="337"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NNG9"/>
    <dbReference type="InParanoid" id="A0A1C7NNG9"/>
    <dbReference type="OrthoDB" id="8119704at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052689">
        <property type="term" value="F:carboxylic ester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46118">
        <property type="entry name" value="PROTEIN ABHD11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46118:SF4">
        <property type="entry name" value="PROTEIN ABHD11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00111">
        <property type="entry name" value="ABHYDROLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="3">
        <location>
            <begin position="37"/>
            <end position="271"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008645"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OBZ90682.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="307" mass="34516" checksum="2124264D2CD39B28" modified="2016-11-30" version="1">MLRSTRLKPLLTYRAYSTKAVELSFDKHAIRPSQDSPLLICHGLFGSKKNWSSLAKAFSSRLSRDVYTIIIKKDLRNHGDSPHSEEHTYEAMTTDLVEFISKHNLKAPILLGHSMGGKAVMATALQHPEMVSKLVVVDMPPVAMTLSRNFATYVDAMREIEAANVSKQSEADKILAKYESNIGIRMFLLTNLRRSDNNVFQFRVPYEILGRSLPSIGAFDIPSHLSYPKPTLFIAGGKSPYRIPFEEQSEWVNQLFPQSRLEVVEQAGHWGKGIEDISVNMTDSEVNVVHAEKPDIVLTSVTQFINN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NNZ4</accession>
    <name>A0A1C7NNZ4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">rRNA-processing protein EFG1</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">rRNA-processing protein efg1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="primary">EFG1</name>
        <name evidence="10" type="ORF">A0J61_01277</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the EFG1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000038">
        <property type="protein sequence ID" value="OBZ90690.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NNZ4"/>
    <dbReference type="FunCoup" id="A0A1C7NNZ4">
        <property type="interactions" value="49"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NNZ4"/>
    <dbReference type="InParanoid" id="A0A1C7NNZ4"/>
    <dbReference type="OrthoDB" id="47732at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030688">
        <property type="term" value="C:preribosome, small subunit precursor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000462">
        <property type="term" value="P:maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019310">
        <property type="entry name" value="Efg1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050786">
        <property type="entry name" value="EFG1_rRNA-proc"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33911">
        <property type="entry name" value="RRNA-PROCESSING PROTEIN EFG1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33911:SF1">
        <property type="entry name" value="RRNA-PROCESSING PROTEIN EFG1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10153">
        <property type="entry name" value="Efg1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0698">rRNA processing</keyword>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="175"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="70"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="198"/>
            <end position="210"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006916"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00018689"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00019827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OBZ90690.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="210" mass="24565" checksum="AFC31A92A8C2C453" modified="2016-11-30" version="1">MKITQHAGKIKKKVRDIKRMLNKSDKLPAQATTEAKRKLRALEFELGEKMIDEQERTKAAKYHKIKHFERKKVMRKLKQAKRALQENSDETKTAELQSKVDDVEIKLLYTTHFPKSLHYVSLFPNSNEQDPTSSARREKMLNEIRKALLDGDKDLSLLQKRYRDEYKEKLIKRGTIAPVAPVDEEMTESKPEKNTSDSSDEEKDDFFEKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NP05</accession>
    <name>A0A1C7NP05_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Phosphate transporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">pho-4_1</name>
        <name evidence="9" type="ORF">A0J61_01085</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Sodium-phosphate symporter.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Membrane</location>
            <topology evidence="1 7">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000031">
        <property type="protein sequence ID" value="OBZ90861.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NP05"/>
    <dbReference type="STRING" id="101091.A0A1C7NP05"/>
    <dbReference type="InParanoid" id="A0A1C7NP05"/>
    <dbReference type="OrthoDB" id="260807at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005315">
        <property type="term" value="F:phosphate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035435">
        <property type="term" value="P:phosphate ion transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001204">
        <property type="entry name" value="Phos_transporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11101">
        <property type="entry name" value="PHOSPHATE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11101:SF80">
        <property type="entry name" value="PHOSPHATE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01384">
        <property type="entry name" value="PHO4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 7" id="KW-0592">Phosphate transport</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2 7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="7"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="45"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="87"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="119"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="147"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="179"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="215"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="504"/>
            <end position="527"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="279"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="293"/>
            <end position="302"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022592"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU363058"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OBZ90861.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="533" mass="57677" checksum="84C52C3A797F3091" modified="2016-11-30" version="1">MMEPYDYTWMFGVTMVFAFMDAYGIGANDVANSFATSVASGSLSLAQACFVAIFTEFLGALLLGAHTADTIKGGILSVRRFADVPEVLMLCMTCAIIGSSTWVLFATKNGWPVSTTHSIVGAVLGVGIAAFGGGSINWGWSGVGQIICSWFLSPIFAGIVSAIIYSITKYGILRQRDSIKWALRIIPAYFFFTTAIEAFYLIYKGAPGTQASKMNVGEIIGIAFGIGAFFALFAILFFCPWLKRRVVGREELRWYHIFVIPFLGPRPVVERLPQSKEVVPEETIESSGSSANEETKYVKTEEQGPQPAQDEQSPAPVSKLQYAKEKFLSIVLHGIRKDVRNLENNHVKSVHDAAEVYDSDVEYMFSFLQVITACMASFAHGSNDVSNAVGPLSAVYDIWQTAEVDVTGKVAVPLWILAYGGVAIDLGLATYGYNIMRSLGNNIILFTPTRGFSAELGAALTVLTCSKLGLPVSTTHCITGATAAVGLCNGKIGAVNWKMLTWCFFSWILTLPAAGLVAGLLFAFCAYGPTIYQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NP12</accession>
    <name>A0A1C7NP12_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_02955</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000119">
        <property type="protein sequence ID" value="OBZ89004.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NP12"/>
    <dbReference type="InParanoid" id="A0A1C7NP12"/>
    <dbReference type="OrthoDB" id="2279273at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ89004.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="169" mass="19287" checksum="94D05A673E34F07B" modified="2016-11-30" version="1">MTDSQNDEKSQCKTDGSIQVSDLKSLELLLIQISSCFGNTDKTNLNFDHHKGMFGAFSVLKCISDDFSFASVEDFIKQVVSLAEDKYTHLYLWSLSYTKEGLFDLFLEASLLVQQGYETRQDYLPELKNLENSIRNVLLLRERHYEAKADYRCTDKQGSSLADLVNQSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NPH0</accession>
    <name>A0A1C7NPH0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Arrestin domain-containing protein C31A2.12</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_01617</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000053">
        <property type="protein sequence ID" value="OBZ90336.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NPH0"/>
    <dbReference type="STRING" id="101091.A0A1C7NPH0"/>
    <dbReference type="InParanoid" id="A0A1C7NPH0"/>
    <dbReference type="OrthoDB" id="2333384at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030674">
        <property type="term" value="F:protein-macromolecule adaptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031625">
        <property type="term" value="F:ubiquitin protein ligase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070086">
        <property type="term" value="P:ubiquitin-dependent endocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.640">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014752">
        <property type="entry name" value="Arrestin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011021">
        <property type="entry name" value="Arrestin-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011022">
        <property type="entry name" value="Arrestin_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050357">
        <property type="entry name" value="Arrestin_domain-protein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11188">
        <property type="entry name" value="ARRESTIN DOMAIN CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11188:SF17">
        <property type="entry name" value="FI21816P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02752">
        <property type="entry name" value="Arrestin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00339">
        <property type="entry name" value="Arrestin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01017">
        <property type="entry name" value="Arrestin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="E set domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Arrestin C-terminal-like" evidence="1">
        <location>
            <begin position="174"/>
            <end position="315"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM01017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ90336.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="362" mass="41236" checksum="324F3CCE16DDF5E8" modified="2016-11-30" version="1">MIEKLLSNSQIKINVENDHLILHGSPTESVGCVLRGTMIIKLKEPTKIKSISLEFSGKCNTSWLEEIDHLSHNSSEQEHPILSHVWPFLPKQSKSYMIPAGTYSYAFELALPGNLLESTYIPGFYTVQYQLKGTIERGKLLPNISEKARVLVSRLSSHASNSDLLEPSMVTNQWGNKLKFEITLPKRLYTYGDTIPVSAIVHFLDPTFHLRIESLTSYFKEHVYCCRQSYGRSHKRILCSFYHERFRPSRHTPGKWSLVQNVQLPSSPFELQCDNRNETICIRHRLKVILSVINKEGHTSKITVNLPIVITASTQVVLPSYDEIGLTLPYNPASVMVNSMIPYDRSLPSYHSVVYGSLAYFH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NPJ0</accession>
    <name>A0A1C7NPJ0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Tc1-like transposase DDE domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_01028</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000028">
        <property type="protein sequence ID" value="OBZ90928.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NPJ0"/>
    <dbReference type="STRING" id="101091.A0A1C7NPJ0"/>
    <dbReference type="InParanoid" id="A0A1C7NPJ0"/>
    <dbReference type="OrthoDB" id="2428500at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ90928.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="112" mass="12060" checksum="C4E75D71985C5C11" modified="2016-11-30" version="1">MSLKGLPELSTTVPASESITITILGAISSVGVIGIYLTKPIMGVEVKKRRADGQDTATKAKVGTRVQHCLYCLSDVMGTLHKSSMKGFYLVIDNAPIHNPTTIRNLIEARGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-06-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NQF6</accession>
    <name>A0A1C7NQF6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_00606</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000014">
        <property type="protein sequence ID" value="OBZ91343.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NQF6"/>
    <dbReference type="InParanoid" id="A0A1C7NQF6"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ91343.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="61" mass="6752" checksum="3C6C8B31078EFDDE" modified="2016-11-30" version="1">MSDLFRLCDNVTKGMTLALLTSNRKSDKAVRSVSHICTLQLACVLEYCTVVDVIMNIQDSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NQJ4</accession>
    <name>A0A1C7NQJ4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Ral GTPase-activating protein subunit alpha-2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">RALGAPA2</name>
        <name evidence="6" type="ORF">A0J61_00711</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000017">
        <property type="protein sequence ID" value="OBZ91240.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NQJ4"/>
    <dbReference type="InParanoid" id="A0A1C7NQJ4"/>
    <dbReference type="OrthoDB" id="19311at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051056">
        <property type="term" value="P:regulation of small GTPase mediated signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.11210:FF:000001">
        <property type="entry name" value="Ral GTPase-activating protein subunit alpha-1 isoform 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11210">
        <property type="entry name" value="Rap/Ran-GAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035974">
        <property type="entry name" value="Rap/Ran-GAP_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000331">
        <property type="entry name" value="Rap/Ran_GAP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046859">
        <property type="entry name" value="RGPA/RALGAPB_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027107">
        <property type="entry name" value="Tuberin/Ral-act_asu"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10063:SF11">
        <property type="entry name" value="RHO GTPASE-ACTIVATING PROTEIN CG5521-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10063">
        <property type="entry name" value="TUBERIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20412">
        <property type="entry name" value="RALGAPB_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02145">
        <property type="entry name" value="Rap_GAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111347">
        <property type="entry name" value="Rap/Ran-GAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50085">
        <property type="entry name" value="RAPGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0343">GTPase activation</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rap-GAP" evidence="5">
        <location>
            <begin position="1836"/>
            <end position="2004"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="226"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="546"/>
            <end position="569"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="778"/>
            <end position="841"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="899"/>
            <end position="980"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1005"/>
            <end position="1024"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="50"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="226"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="781"/>
            <end position="813"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="899"/>
            <end position="910"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="911"/>
            <end position="926"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="933"/>
            <end position="966"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="967"/>
            <end position="980"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022468"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OBZ91240.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="2004" mass="225186" checksum="B656055DA24EE794" modified="2016-11-30" version="1">MRKAIPSSSLKKGLVHTTDKPSLPPNIILNQHTETNLDVPILPSNSTFTLSSKEDKNEKLKKKAKNFLDERQKTKSRAQSLWSFIDATNTFDQARFFQENAEQVFQVVFDTCMHQIEKIKHKSERPQSWNSKELVGLQKTLLLLRKIFLYVPELMRNGWQRSNIAIILTHILDHGNHPRLRALGFQLLLLWLNDQVVEYPECMNLFANAISLDLFVLDDIQPYGPSTSTNTSNTNQAPVAPAPMHATTHLSSPTQIHDMDEAATNTASNKLHTGGLQFVKKLRESHANPDRQVNHGLSRSDKIKSSPIQLNQRLILGDDTPSLYPNPSQPTFNDSIVLIHIFISNLVRLAYVAAGSPPPPDEYDYPPGDHFEPDDGIATGVGIDAATASAKFLFKIFRTCYMTKFVPLISKSLSVEGSLKTGICGFPSCPPSILRSLLKFLIGYCLDNDSHHANLHWPQTSHASGAATAVSSPATPILKSIVLSSHETREMLHEIIRQSLVLPCTNPQYRDITRGAIHILGVWILGNEDERPSFLRRSGSVVTRSSSTASVSNNSISNDPILSSSSSSRVFSSSPVEEYAPQLPLKNTTMNEDYSDANTFLRRYLLMIKLVFEDRRQDATQQSNRDVQAFNAQQVADWEGLVALYKDAISVYRSITVSKGGIDIEWESWELLLQCLLDIQQWFMSQPEKYSRIPVQSLAEELADYIWETLFHAFIRAKITHMELWHHLKTHLGSSMRWPQSLNQWVRIMQKLTRLLSSRLYKVDYELYPDTKHRLVEEFPSNNTNTSGTTGRSNNNNTNSGASIHSRGGNSSRSKSKTRHNNIQERQMLESTPEPEGSMSNLLRNLSSASLSDIANPFKTDRKSASLALVVDEELEDAHIDYGVTNTVKFGIKNIKPANSSSNTPSHASSGHNTHNASTVQPSSASIGKRGNTFHSSTNNSSTNNTNGHVLRGRSGSINSNAGNNATLNHTATSDKSTGRRTISIQQLDTLWQDSGSKLLNFVHHGDNTQPTIVKSSAKDDDKKNTLEWDHASASSIEEISTKSNRTSSSSAWPAGESLSVMANPAAVSEKLPVSLGSFRSPEFLVLNNVSYDGLQVLSIWKNMLLTIGNINAIERPRNHVIAIQCVVEIWDTLCLVRAQQPYRDIPIPAMYEVAPWLFQATELPESFNAGKAVAYGSLCRLMSQRPEEKVPEGYYAAFYKCILEGLASENNTIIHSILINSERLFGSCLPGVHILIPSFIDTIEKQLLNDSIPHNVSPMVKKSCIVILGSLVSISNHLKDVSIDTSNLDLDWIEGIQGNQFNFADVKLWLKNIFIRLVSSEAASPQPEEDVDLRCMLLGALSALAMDEMLTPENPLQEFVHECILSLVNHLYWSNLSVVNTVSDCLVAMAHIYREDLDKEGVIVQEILTRIIDSLNVHLKYYEQNTKCGRGFVISKLFSCLLEWIMSIEPTILTETDLCQLVFDVIELALHVTSDDNEKRLPHPPRTGDTKKKETPFKFKLMSDKRPTLHEDIPAAATATHSSETSENDQSYVKESAEAILLHLLHHFNNFAPPYGPSIIHSTIVGPGVSQDDLGYHEYQYFSFNDTTIIAFVELPKSEERGVQARIIIRDLTGRYVWDTQIESPDKPLLQAQEEKAIVDSEQEFSLRDNIAIRQQTIPDEIEHKGLLSNQQKEEEDPMKALLKQIGDSHPDCLLDPNLPLDVPSTSTPLQLEMLKDLDNQLNDYLQNESENNNQQKSDIQLWYSKMNALRKKETPEENKVLEKGDTSSLQSYLISNFSLRKDFLPAFPLEAEKPNVPFQQSRLLMSHMGLIHYKHLKDGSFQMLNKTPALYRDLRGLDRKHGRETMKIGLIYVAHGQEDEQSILQNSRGSERYNAFVNSLGWEIDIATHTGYLGGLERNLTNGSRATYYCSSTIEMIFHDVTKMPTDTSDPKQLKKKRHIGNDHVHIVWNEHDRDYRIDTIGGDFGDAQIIVTPLPNSLYSIQVYRDPKVSWDDFENGKFQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NQJ7</accession>
    <name>A0A1C7NQJ7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Glycogenin-1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">gyg-1</name>
        <name evidence="4" type="ORF">A0J61_00544</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000012">
        <property type="protein sequence ID" value="OBZ91405.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NQJ7"/>
    <dbReference type="STRING" id="101091.A0A1C7NQJ7"/>
    <dbReference type="InParanoid" id="A0A1C7NQJ7"/>
    <dbReference type="OrthoDB" id="2014201at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="entry name" value="Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002495">
        <property type="entry name" value="Glyco_trans_8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050587">
        <property type="entry name" value="GNT1/Glycosyltrans_8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015338">
        <property type="entry name" value="GT64_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11183">
        <property type="entry name" value="GLYCOGENIN SUBFAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09258">
        <property type="entry name" value="Glyco_transf_64"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01501">
        <property type="entry name" value="Glyco_transf_8"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glycosyl transferase 64" evidence="3">
        <location>
            <begin position="309"/>
            <end position="518"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF09258"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OBZ91405.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="534" mass="61284" checksum="CA3710083D007CAB" modified="2016-11-30" version="1">MMYNMNIYLNLQTKVLSDNSIQANKKNAYVTFLCDDVMAEAAQVLVYSLKQTDTQHDIVVLVLNEVTQPSRDRLIHLGAKIINVNQIKYPWVSAAARKKGFNKACRYSKLNLWSLTQYQKIVFLDADTMVVQPLDELFDYPQFSAAVDIGGVLNTGVFVAEPNEETYRDIMATYLNAPSYNRGDQGFLNYYFNQTAHTLPGNYNLMVKFTHFSTLARSFIIQDKVKVLHFTSDTKPWNFHFLHHPEWRENYDGYLFGLWTKALRHKNLELAKAGLLKEGGRNQERVDYVCELQLHSNYGRRYPNTKQLTVILDLSSTTDTLSLEAILRFYASSKVVNQIFIRENQIQLDKTYLRKLRIRKPVNIIPPTPYPSSNNKFNPIQGIKTDAVLLVDGNMFDSVQEFEFAFDVWNKNKDSIVGYQPYSHKTVDSVGRNHQYNMMSSKMMLMKSDFLYAYSCLLPSQIHHYVDQHPDCLDVAINMLTSGMTGAAPLLVDNKFVNHSITSSLSGSNCIRDLTSFFDDKNTLVLNNQMVKSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NQY6</accession>
    <name>A0A1C7NQY6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Glycosyltransferase-like protein LARGE2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">gyltl1b_0</name>
        <name evidence="7" type="ORF">A0J61_00422</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000009">
        <property type="protein sequence ID" value="OBZ91531.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NQY6"/>
    <dbReference type="STRING" id="101091.A0A1C7NQY6"/>
    <dbReference type="InParanoid" id="A0A1C7NQY6"/>
    <dbReference type="OrthoDB" id="411524at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015020">
        <property type="term" value="F:glucuronosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042285">
        <property type="term" value="F:xylosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035269">
        <property type="term" value="P:protein O-linked glycosylation via mannose"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="entry name" value="Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051292">
        <property type="entry name" value="Xyl/GlcA_transferase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12270:SF25">
        <property type="entry name" value="GLYCOSYLTRANSFERASE-LIKE PROTEIN LARGE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12270">
        <property type="entry name" value="GLYCOSYLTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13896">
        <property type="entry name" value="Glyco_transf_49"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0735">Signal-anchor</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004606"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OBZ91531.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="427" mass="49574" checksum="400A8E86AB3C5173" modified="2016-11-30" version="1">MKESSTVSKILKLVGVVYLACSLLYATFHLFGMDWLPSQSSSLSGFGNSYQTESQSVSQLQQRYRSSQMVSWTNADGAYNQSIPEDLVLSKVFSDSMGPSKVIPYYFRATEQFDQEDVTISTLVTHNRLPVLSRLATRYKGPISVAIHVNDDHTKDVILSDLHEMYDNNPDVGKYVDIHLVVDKFDRQFNMWRNVAKFFARTDFIMMLDVDFHLCTDFRESLKKSPQLMDVLRQGKGAIVVPAFEYIAEEDGEDWRLFPKDKEALINIVLAEKIDMFHLGWTRGHASTDYKKWYQSSEPYKVTDYNYSYEPYVIFKKEGTPWCDERFVGYGANKAACLYEIYLAGIDYWVLPNDFLIHQTHHYPEDTRAKERKYNKKLYDYFREEVCLRYSRLMISAGLWDTSIADNLKGECAKIKGFKEIVARVQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NR83</accession>
    <name>A0A1C7NR83_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">CRAL-TRIO domain-containing protein C23B6.04c</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_00429</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000009">
        <property type="protein sequence ID" value="OBZ91528.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NR83"/>
    <dbReference type="STRING" id="101091.A0A1C7NR83"/>
    <dbReference type="InParanoid" id="A0A1C7NR83"/>
    <dbReference type="OrthoDB" id="75724at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008526">
        <property type="term" value="F:phosphatidylinositol transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00170">
        <property type="entry name" value="SEC14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.525.10">
        <property type="entry name" value="CRAL-TRIO lipid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001251">
        <property type="entry name" value="CRAL-TRIO_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036865">
        <property type="entry name" value="CRAL-TRIO_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011074">
        <property type="entry name" value="CRAL/TRIO_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036273">
        <property type="entry name" value="CRAL/TRIO_N_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052578">
        <property type="entry name" value="PI_Transfer_CRAL-TRIO"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45824">
        <property type="entry name" value="GH16843P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45824:SF29">
        <property type="entry name" value="GH16843P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00650">
        <property type="entry name" value="CRAL_TRIO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03765">
        <property type="entry name" value="CRAL_TRIO_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01100">
        <property type="entry name" value="CRAL_TRIO_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00516">
        <property type="entry name" value="SEC14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52087">
        <property type="entry name" value="CRAL/TRIO domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46938">
        <property type="entry name" value="CRAL/TRIO N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50191">
        <property type="entry name" value="CRAL_TRIO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CRAL-TRIO" evidence="2">
        <location>
            <begin position="122"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="7"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ91528.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="318" mass="37210" checksum="C290AECD727CA119" modified="2016-11-30" version="1">MNVFNRLKSNSNASDKPPVVNTNLMEGPISHEPKLTPTNKYTVVEQPPLTDEQKEKVVKLKTYIESIMLPGTDAYYPSERGFVTDNTVKRYMRARKWDFEQAKTMLENTVRWRRDYRPDELDPEYIKPEAETGKMYYNGFDKCGRPIWIMRPRLQNSKDGERQIKHIVYSLERGIRLMPEHVENLAIIIDFKDASSSHNPSIATCKKFLDILGNHYPERLGVAFIVKSPWFFVATFKVIAPFMDAVTRNKIKFVIDDKDDKEKKNDISNDWVNLKDYIDADQLETDYGGSFNYAYQIEPYWKSLLEKTGNPHKIIEYN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NRD3</accession>
    <name>A0A1C7NRD3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Transcription factor cbf11</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">cbf11_1</name>
        <name evidence="10" type="ORF">A0J61_00283</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the Su(H) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000006">
        <property type="protein sequence ID" value="OBZ91662.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NRD3"/>
    <dbReference type="FunCoup" id="A0A1C7NRD3">
        <property type="interactions" value="231"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NRD3"/>
    <dbReference type="InParanoid" id="A0A1C7NRD3"/>
    <dbReference type="OrthoDB" id="5600360at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001228">
        <property type="term" value="F:DNA-binding transcription activator activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.80.10.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1450">
        <property type="entry name" value="LAG1, DNA binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015350">
        <property type="entry name" value="Beta-trefoil_DNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036358">
        <property type="entry name" value="BTD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040159">
        <property type="entry name" value="CLS_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008967">
        <property type="entry name" value="p53-like_TF_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015351">
        <property type="entry name" value="RBP-J/Cbf11/Cbf12_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037095">
        <property type="entry name" value="RBP-J/Cbf11_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10665">
        <property type="entry name" value="RECOMBINING BINDING PROTEIN SUPPRESSOR OF HAIRLESS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09270">
        <property type="entry name" value="BTD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09271">
        <property type="entry name" value="LAG1-DNAbind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01268">
        <property type="entry name" value="BTD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01267">
        <property type="entry name" value="LAG1_DNAbind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110217">
        <property type="entry name" value="DNA-binding protein LAG-1 (CSL)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49417">
        <property type="entry name" value="p53-like transcription factors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="RBP-J/Cbf11/Cbf12 DNA binding" evidence="8">
        <location>
            <begin position="145"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="domain" description="Beta-trefoil DNA-binding" evidence="9">
        <location>
            <begin position="287"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="39"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="81"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="51"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="86"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="97"/>
            <end position="118"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009704"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM01267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM01268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OBZ91662.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="681" mass="76274" checksum="45A351B91D9BFAF9" modified="2016-11-30" version="1">MERKAHIITEQVFGSSRKIQFIGLPSTPMDSLLSAIDHEHHRTHTSPSDYRSIEKEETERASSSVHQTMSIESLLANNSLSESSHHHTANYNHHRQSASASTHEVSIASLLTSDNTSNQKRRRDEEEQRYRKKQQTKKSVNEKTIITCLHASVAQKSYGSEKRFLCPPPIVQITSPPSSKLTNEQRSEKMQLSMSVVCENGDKVLEQRSLLDENQTGSFRYLHVTGTAKAKQFNLKVDLLPTTSSPMSPHQQQDAEPVEPLASFISKPVSIISKPSKKTAKTRNVSTCILTDSSVCLFNRINSQTVRTKYMTSGNNMLCARNNTWSPFDIIVVNQPKLPQPHKLTNKHLPHTPMPNNRFNARIQLAQPVNSIAQTTASNNKIPAHITYGTEIILRDSQTGITSPSLIIRKVDKGRIAQCAYGPVSQMQKIALQLASTLHTQPVYLSAAGALNDTALHHHHHNDSSSMNNSTTWLDFSPSRLVKPEKSSFELVFEEVDDFLCWTIVGINKFEYEFYENEALDSKQEITEVQETEPEVSTMTTPPPSPRHITPFPVLTKIEYNPQEHTLDVIGQHLIQAAPVPRLLDLWLGTHGPLVTRVSQPPQSHTPHETHWSVQLPSTQDLLVANHDLLKTFSDGRRNLELSLLLVRQDGLVYHTGKALSCDIIQDAGRWTVVAASSHSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NRT6</accession>
    <name>A0A1C7NRT6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Pleckstrin homology domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_01983</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000070">
        <property type="protein sequence ID" value="OBZ89964.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NRT6"/>
    <dbReference type="STRING" id="101091.A0A1C7NRT6"/>
    <dbReference type="InParanoid" id="A0A1C7NRT6"/>
    <dbReference type="OrthoDB" id="5865767at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.50">
        <property type="entry name" value="Transcription Factor, Ets-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041681">
        <property type="entry name" value="PH_9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013761">
        <property type="entry name" value="SAM/pointed_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37283">
        <property type="entry name" value="PH DOMAIN-CONTAINING PROTEIN YHR131C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37283:SF1">
        <property type="entry name" value="PH DOMAIN-CONTAINING PROTEIN YHR131C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15410">
        <property type="entry name" value="PH_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pleckstrin homology" evidence="2">
        <location>
            <begin position="177"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="84"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="90"/>
            <end position="102"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF15410"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ89964.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="297" mass="34270" checksum="AECA009C6CFB3648" modified="2016-11-30" version="1">MLKPSLPIIIIQDTNQHPISTTQDVLSQIELDKYSIQLKGVDLDQFMQMTDEKDFRQYGVRKQRDCQKLSSTAKSIRRSSVGSSSLCTVNEEEEQQQLDENDTSLRPKDDAAWPNSIYGFTKSAQSRRHSLPVYSEVDSSDVDTGRRHSYHIPRLVNQQEELLPSYSCTLHKLGKAKAKIEFEFPGKRRRRRPWRDIYMELKGTMIRLYEMKSNDEYHYLPTLTAYYQQSIKYTPLVDLSLAYAKVEQAQDYKKRPNVFRVQTASGPQVLFQVQTNAAVVLWVEKILAGCMIAVGFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NRW8</accession>
    <name>A0A1C7NRW8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Conserved oligomeric Golgi complex subunit 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">Cog1_0</name>
        <name evidence="8" type="ORF">A0J61_00271</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Golgi apparatus membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the COG1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000005">
        <property type="protein sequence ID" value="OBZ91710.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NRW8"/>
    <dbReference type="STRING" id="101091.A0A1C7NRW8"/>
    <dbReference type="InParanoid" id="A0A1C7NRW8"/>
    <dbReference type="OrthoDB" id="46189at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017119">
        <property type="term" value="C:Golgi transport complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006891">
        <property type="term" value="P:intra-Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033370">
        <property type="entry name" value="COG1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31658">
        <property type="entry name" value="CONSERVED OLIGOMERIC GOLGI COMPLEX SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31658:SF0">
        <property type="entry name" value="CONSERVED OLIGOMERIC GOLGI COMPLEX SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0653">Protein transport</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004395"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006653"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00020978"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OBZ91710.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="635" mass="73324" checksum="31F3785EA3AAB115" modified="2016-11-30" version="1">MKSSDSLVHRLAHQLKEVALVFKTTVVQIVSIFVLLEDDRQKPMIESYVNSFKQTFLIPSSRNAETSISQSAITRLFSPSSNIHLIVRFLPESIQQYLPQFDPSTMPSIEDIRQSIDGWISSVEQYLHHHLDERLQAVDKHSDLVQIRTKIWEALREDEIAKDKKNKWRTANQAVLTSSYSVWNNLYRDSFNRHTKRLIDNSLKQLINQPGSTIWNSLVDPKTLKPQKDLSVTMHVWPDLNSKHQAAFVLPNLSSAQEIRSFKTSLTETVYDRTSSLSLLQNEFDMILSDITKDAKSYLMNGSNMNDECFHVKNDTNMIKNYFEDKCFETIQSYSREVNILLKRIAGWTDYETANGASIFLGRLVRNICLLSKELPNALSISIDTPPTFELRSRIDQNPKYSQAQKILTDTFHDSHNIWLDYLQKKYAEDLKKTLLSTKWNDQCPAQLVWDHVEADIKLPVQSTNSIARGLYNVCEELQRFNSTLLDKTIMTNLRQKLQDTVNQVYETCIRQVELTENGALQLMFDYLFLCTILQQDTKLTNNSVVQFLKSQIDLINWASYEPHFKPSVNKFYIKQSLIFGVLTNANNETYERARKVVSSQQQGHHNVLPLAPQAQRFTLLPIGHFASSSSIRTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NS90</accession>
    <name>A0A1C7NS90_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">FAS1 domain-containing protein fsc1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">fsc1_0</name>
        <name evidence="3" type="ORF">A0J61_00021</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000001">
        <property type="protein sequence ID" value="OBZ91918.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NS90"/>
    <dbReference type="FunCoup" id="A0A1C7NS90">
        <property type="interactions" value="32"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NS90"/>
    <dbReference type="InParanoid" id="A0A1C7NS90"/>
    <dbReference type="OrthoDB" id="14252at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.180.10">
        <property type="entry name" value="FAS1 domain"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050904">
        <property type="entry name" value="Adhesion/Biosynth-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036378">
        <property type="entry name" value="FAS1_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000782">
        <property type="entry name" value="FAS1_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10900:SF77">
        <property type="entry name" value="FI19380P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10900">
        <property type="entry name" value="PERIOSTIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02469">
        <property type="entry name" value="Fasciclin"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00554">
        <property type="entry name" value="FAS1"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82153">
        <property type="entry name" value="FAS1 domain"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50213">
        <property type="entry name" value="FAS1"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="717"/>
            <end position="743"/>
        </location>
    </feature>
    <feature type="domain" description="FAS1" evidence="2">
        <location>
            <begin position="8"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="domain" description="FAS1" evidence="2">
        <location>
            <begin position="145"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="domain" description="FAS1" evidence="2">
        <location>
            <begin position="418"/>
            <end position="559"/>
        </location>
    </feature>
    <feature type="domain" description="FAS1" evidence="2">
        <location>
            <begin position="564"/>
            <end position="705"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50213"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ91918.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="757" mass="85217" checksum="E9DFF6DE0052000B" modified="2016-11-30" version="1">MLAICLKTKTIIDVLSEDKRYETLLSYLEKNQMIEYVKKIESGTFFAPDNNAFKQTNQTIDRSTLLYHIIKKGMKSTDFYHGQLKETLLIRSGYLVPDNNSGAGQRIKFSKKGDDISVNQAKIIQSDLQVNNKTYIHAINSVLMPPSLLGDMVTEDRSKLIHEWMASTGLLDMLHQKRPFTLFLTTSSTPLDKFNLIESSYLTSSHGQDDLSTFIQYAIIDKAIFLDEFNAGKTTYKSLSGDALVLTSDKKSAAMAVNDMPIKQSDIIAANGVIHEISDTFRPPSIIFDTRKYLYGSNSTHMVDLMDNYNISDYYLKDRHNATFLIPALDTINQSIVSKDWVEYHILHQPYTLKKGSFLLDSEFKSPDLGYQRQKMLVSVESDNHPNSIYFDRARVIGESININQDVIYQLSEPVTVPGNIFERLVLDLDVSTFIATLYVSEVIEEIKNTHGLTLFAPTNEAFQNLGLVAKYLVHPTAKTQLQTVLRYHAAPSLLYYDDMKQPLIEIDTLANATLNISQKEDQTVVVGSPGGNEHTTGKITQHDMLVSNGVVHKISEVQIPSQINITNRHVLIGIESKLMMQILEKTGLLSVIDEKEMVVLAPSDKAFSHLDIEALLNDSYELERLAKLHIVPTAWQDRWIVQQEDRRSEYATLLSDDDKVAIRENEKGELFVEVKNGGDNNRAHVTGLGRVPAGGGVIEIDTVLMPIRRGLFGLPFAWSIVVLLMIIGITGGLIAIIGFFGYKIHSRRRLGYRPIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NSC8</accession>
    <name>A0A1C7NSC8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Multiple RNA-binding domain-containing protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">mrd1</name>
        <name evidence="5" type="ORF">A0J61_00563</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000013">
        <property type="protein sequence ID" value="OBZ91376.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NSC8"/>
    <dbReference type="FunCoup" id="A0A1C7NSC8">
        <property type="interactions" value="950"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NSC8"/>
    <dbReference type="InParanoid" id="A0A1C7NSC8"/>
    <dbReference type="OrthoDB" id="439639at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030686">
        <property type="term" value="C:90S preribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032040">
        <property type="term" value="C:small-subunit processome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042134">
        <property type="term" value="F:rRNA primary transcript binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000480">
        <property type="term" value="P:endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000447">
        <property type="term" value="P:endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000472">
        <property type="term" value="P:endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034462">
        <property type="term" value="P:small-subunit processome assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd12317">
        <property type="entry name" value="RRM4_RBM19_RRM3_MRD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd12320">
        <property type="entry name" value="RRM6_RBM19_RRM5_MRD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.330:FF:000442">
        <property type="entry name" value="Multiple RNA-binding domain-containing protein 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050502">
        <property type="entry name" value="Euk_RNA-bind_prot"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48025">
        <property type="entry name" value="OS02G0815200 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48025:SF1">
        <property type="entry name" value="RRM DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="4">
        <location>
            <begin position="243"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="4">
        <location>
            <begin position="429"/>
            <end position="501"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="4">
        <location>
            <begin position="544"/>
            <end position="627"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="4">
        <location>
            <begin position="644"/>
            <end position="721"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="61"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="731"/>
            <end position="763"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="86"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="122"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="165"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="196"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="224"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="731"/>
            <end position="742"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OBZ91376.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="763" mass="86478" checksum="CBFC10CAB2C33119" modified="2016-11-30" version="1">MKTQWGTSRRFGFIGYKNEATAEAAIQYYNNTFINTSRIAVEKAIAYGSENLPRAWSKYSEGSSAHDRLTGSNKKKQSEFAVEETDAFRDKQRKDKEKEEFVNKLNADKNDPKLKEYLDVMTSRSKSKTWTNDESAIEEKKKEEADESTTVNYADSDDDLYDELPVSKKQDKTGDKAEDKAEDKAEDKAEDKAEDKAEDEEMEETVEGDETEAMEEDSQEQTEEDRKKKEEKEDAKDKIQDTGRLFVRNLSYACTEQDLRDLFGQYGALSEVHMPIAKDTKKSKGYAYILYLLPEHAVSAYESLDMKDFQGRLLHILPANEKPPSKDEEILGLNGTKLSAVKKEKEKKRRNLAGNDFNWNSLYMSADAIAESIADRLGVSKSEVLNPDADNVAVRLALAETQIVNETKEFFEKHGIVLDTFGKKDRSDTIILVKNIPYGTTEEDLRELFGKFGELGRLLIPPAKTIAVVEFLEPSEARTAFKSLAYRRYKDSLIYLEKAPSGLFKNSFVRDPNSNNDKKEPEKVKSAADLLASSADTDDSGDITTLFVKNLNFDTKPESLQKAFKGITGYRSSRINVKPDPKHPGKTLSMGFGFVEFDTKSNALKALNAMQGYQLDNHALELKLSHRKADTNNKSKKSKTPDTTKLVVRNVPFEATDKDLRELFGTYGQLKSLRMPKKFNGGHRGFAFLDFLTKQEAKNVYDNMANIHLYGRHLVLEWAQDEDNVESLREKTGKHYAKEESVGGRVTKRQKVDLDGDNDDMLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NVQ4</accession>
    <name>A0A1C7NVQ4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF7905 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_00364</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000008">
        <property type="protein sequence ID" value="OBZ91554.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NVQ4"/>
    <dbReference type="STRING" id="101091.A0A1C7NVQ4"/>
    <dbReference type="InParanoid" id="A0A1C7NVQ4"/>
    <dbReference type="OrthoDB" id="4739136at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057227">
        <property type="entry name" value="DUF7905"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25482">
        <property type="entry name" value="DUF7905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF7905" evidence="2">
        <location>
            <begin position="346"/>
            <end position="655"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="146"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="11"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="157"/>
            <end position="177"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF25482"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ91554.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="687" mass="80180" checksum="F08C7F43CF38E1C2" modified="2016-11-30" version="1">MSIEPEVPYNFEDDEASDNEDGWRDAGVRSVQNTPQRPLVDVYIPNTRSDTPVSRASTRTFTDTTVVSEAAHRNADDAWILPAYCNPSDILGGPNKSRAKEIQRESKSYIEYNAEYNQIDIWGDADAIAKTKQYLDSIAHRLAENDTRTTRKTKKWGRPERELTEKEKRRAERRQAKLDEERRYQGLPAVPQNYNAVFPLPDTHLPLNHFMGDRGEEYFNAIRADCKAFLWYQETGNLVRISADTDESVREAGKRVRNWYLRCNRKPIGSRHRLLQQPTKPWVLRYRKLPQNFVTYIYDSPEGENHMLEKQRLLEPVGHGVPRAISNIQGQPEISLIDVNDSYENELPEHIRRLDAQNEKHIEKSLADGIESLRLNDWMIRMKIRFGSICLIDYPKKQDYLSIDYITDMFRKPRFNSALAPCIGKSEEHLGHLFDFLSNDSEAVEFSENPRTSFIIHAQQYPTAAPPRIPGQREPSRGDMWNTVMRVSFTESGVRKLWNTMTDCHDLVDINCLDIEGNYSWDLKLQYARQLPNNDFDTPHSKFWQALSITPEKRLIMTTFSDYIPNRVTQKTKWLYSWRGYVVEICKDEIWDMMRIERKDRELPVDLTIYEPHRVLYKVSVYREAWVNRFAENLTLKIGEAPNWTLRDFLGSDEENARTIMKTAKDFAAILNAKVPHYWDNAGNSLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MNS8</accession>
    <name>A0A1C7MNS8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">ATP-dependent DNA helicase PIF1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">Pif1_1</name>
        <name evidence="2" type="ORF">A0J61_11850</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01002586">
        <property type="protein sequence ID" value="OBZ78522.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MNS8"/>
    <dbReference type="STRING" id="101091.A0A1C7MNS8"/>
    <dbReference type="InParanoid" id="A0A1C7MNS8"/>
    <dbReference type="OrthoDB" id="3691720at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd18809">
        <property type="entry name" value="SF1_C_RecD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049163">
        <property type="entry name" value="Pif1-like_2B_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10492">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10492:SF57">
        <property type="entry name" value="ATP-DEPENDENT DNA HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21530">
        <property type="entry name" value="Pif1_2B_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0347">Helicase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA helicase Pif1-like 2B" evidence="1">
        <location>
            <begin position="42"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="168"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF21530"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ78522.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="168" mass="18630" checksum="8EB8636110F3C58C" modified="2016-11-30" version="1" fragment="single">MVDEINKYVLDQLPGEETSLFAVDCITQEDSTGAVDRQMPAEYLQSLNPPGLPPSILELKVGMPVMILRNISAERGLCNGTRVTVLSIGEFLLKIKLPNVDGRIEVISRFTLSTLENEYPFTLTRKQFSVRRSFAMTINKSQGQSLKIVGIGLRSPVFTHGQLYVALS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MTR5</accession>
    <name>A0A1C7MTR5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_11720</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01002383">
        <property type="protein sequence ID" value="OBZ80232.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MTR5"/>
    <dbReference type="InParanoid" id="A0A1C7MTR5"/>
    <dbReference type="OrthoDB" id="2379842at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="103"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ80232.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="103" mass="11867" checksum="38D8C21E5C788EB9" modified="2016-11-30" version="1" fragment="single">MTKAPNIFADNDKKNIQLQADGSQMSVRYVNEEGKKKALDFIDSKMIESEKWTAFNTYKLTHMTNRSSNRVEGSHSSLKKFVRSSSGIIVFTTEKIDQLYKQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MU63</accession>
    <name>A0A1C7MU63_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Endonuclease/exonuclease/phosphatase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_11644</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01002292">
        <property type="protein sequence ID" value="OBZ80307.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MU63"/>
    <dbReference type="STRING" id="101091.A0A1C7MU63"/>
    <dbReference type="InParanoid" id="A0A1C7MU63"/>
    <dbReference type="OrthoDB" id="2207231at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.10.10">
        <property type="entry name" value="Endonuclease/exonuclease/phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036691">
        <property type="entry name" value="Endo/exonu/phosph_ase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005135">
        <property type="entry name" value="Endo/exonuclease/phosphatase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14529">
        <property type="entry name" value="Exo_endo_phos_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56219">
        <property type="entry name" value="DNase I-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Endonuclease/exonuclease/phosphatase" evidence="1">
        <location>
            <begin position="268"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="347"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF14529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ80307.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="347" mass="38367" checksum="F48686FC7BDD614B" modified="2016-11-30" version="1" fragment="single">MLKVNNWRVLDIHFPAACVVALLVHNDYVSELTAVFAKAGVMPLVDFNPLDPKHLDDPRLSSLSASDAADKACLVHQGRLLCTLQYIRSPACNAVAADFCARGWIADEQLHKFRKTSSFAVVSPFDASGAVSAVSGKQVFDVEDLDMHDSVDQVPTPSASTPADAVMSANDITITIWNANSLDRLTINTVTQSFTSSSLIFITETWLLPPLRLPTSWQQYHTYGLPVPNMRRGQIGISLLINPDFPYPITPMPSSSPYVLSCQVASTLIHCVYLPPTASLSDSYALSVLRDFPMHRLPHQTNTIICGDINARHNRLLGDTRTTVRGTMLYEWMIEYGLHCWNSVFAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MUL2</accession>
    <name>A0A1C7MUL2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_11514</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01002137">
        <property type="protein sequence ID" value="OBZ80437.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MUL2"/>
    <dbReference type="InParanoid" id="A0A1C7MUL2"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="11"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="23"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ80437.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="70" mass="7923" checksum="783C306767CB1514" modified="2016-11-30" version="1" fragment="single">VKLEKHRKDKKTSDDDMNGRDAENEDESEEADEESESESEDDEAAISQPQERKSKQVSSEGSTSHRKAKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-06-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MUM9</accession>
    <name>A0A1C7MUM9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_11380</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001971">
        <property type="protein sequence ID" value="OBZ80571.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="InParanoid" id="A0A1C7MUM9"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="26"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ80571.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="187" mass="21573" checksum="0270BADC4758FA9D" modified="2016-11-30" version="1" fragment="single">IKYNMAPTPKYVSDLLASSEAIQASLASIVERLDAIEEQNRVLSEQLQQQQQQQVQNPAQQIESMATPIRFPVLNRANPSQGIKTFLSQASPEKSPQELKCYYKDFSSLALRACYMYSEQENNHCTYYKNPPSKGKVAMKKTCFDFLLEKHENLSVLRECDMAWPVEFAVQNAWTEFAKRQYVYDXE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MUV8</accession>
    <name>A0A1C7MUV8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_11339</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001923">
        <property type="protein sequence ID" value="OBZ80612.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MUV8"/>
    <dbReference type="STRING" id="101091.A0A1C7MUV8"/>
    <dbReference type="InParanoid" id="A0A1C7MUV8"/>
    <dbReference type="OrthoDB" id="2289822at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ80612.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="390" mass="45690" checksum="9AF4740894F85C2C" modified="2016-11-30" version="1">MDGINRWIDYSKPTTPTISDFSFDHKKQFFRAVDWQHVLLHVAPTIIAPYLKSSTATDALMDLINACSISLQRSISPGESTYMKSAFTRWGDFLRREISADRYSMRVWTMNNHFAVQNVPELIKQQGPLRYFSCRSLERTIKKYSNMVRSMFAPDVEISNIHTRVNYYKEHRSAETTDSSIGSSSVQERDFLLHPTHPQTTPRLWLKIQRIELCERADFFGASTWQFINALQRYYSRLGLSGSVIDSQQITMAGSMLKDDVYYHSRLHRTNNTLLKRSNHLVLFEAKRASRYWYIGEVLLYFEHNLNGTSRFLALVLVMPDASMDEYGIIRVTYYQQRLNEQFMVCNTLDVITIIGLVRYNDNETDFKAIWPDAKYYQKLDGRIHREELL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MV08</accession>
    <name>A0A1C7MV08_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_11662</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01002312">
        <property type="protein sequence ID" value="OBZ80289.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MV08"/>
    <dbReference type="InParanoid" id="A0A1C7MV08"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="50"/>
            <end position="86"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ80289.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="123" mass="13611" checksum="DBDFE2E2E7F2BCA9" modified="2016-11-30" version="1">MSGSHYLSSLRDRVQFGIGPLRVTRGGSMAGFLSVPGSVSDVMSVIRDSEVLDAHSDTNDDTTGIQDNERPPASLPETPRRVQRKIPVPLPVEKLPEVTPWARESISKLPLMNNWSQNFKTKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MVW3</accession>
    <name>A0A1C7MVW3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_10989</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001568">
        <property type="protein sequence ID" value="OBZ80963.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MVW3"/>
    <dbReference type="InParanoid" id="A0A1C7MVW3"/>
    <dbReference type="OrthoDB" id="2123952at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="41"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="86"/>
            <end position="103"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ80963.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="148" mass="15900" checksum="14B243EA5261FF07" modified="2016-11-30" version="1">MSSPHLQRPPVMAPRQHRHSIQGIPHQHQDKITSPSPPLSPSKQSSHSANLMANSMLNLSLSPSSSSTSSSSCIQPSISTPTSSLANPSRSTNDSWKAEWSQSPPIPSLMDQLSNCTFVATAMDYTTVHYPIYPISATSVPKSTSSTQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MWN5</accession>
    <name>A0A1C7MWN5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">ATP-dependent DNA helicase</fullName>
            <ecNumber evidence="1">5.6.2.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">PIF4</name>
        <name evidence="3" type="ORF">A0J61_10729</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="5.6.2.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the helicase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.6.2.3" evidence="1"/>
    <dbReference type="EMBL" id="LUGH01001348">
        <property type="protein sequence ID" value="OBZ81222.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MWN5"/>
    <dbReference type="STRING" id="101091.A0A1C7MWN5"/>
    <dbReference type="InParanoid" id="A0A1C7MWN5"/>
    <dbReference type="OrthoDB" id="5860629at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043139">
        <property type="term" value="F:5'-3' DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000723">
        <property type="term" value="P:telomere maintenance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010285">
        <property type="entry name" value="DNA_helicase_pif1-like_DEAD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10492">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10492:SF57">
        <property type="entry name" value="ATP-DEPENDENT DNA HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05970">
        <property type="entry name" value="PIF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0227">DNA damage</keyword>
    <keyword evidence="1" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="1" id="KW-0234">DNA repair</keyword>
    <keyword evidence="1 3" id="KW-0347">Helicase</keyword>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA helicase Pif1-like DEAD-box helicase" evidence="2">
        <location>
            <begin position="49"/>
            <end position="218"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU363044"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF05970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ81222.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="220" mass="24012" checksum="CA72E2DA46D16745" modified="2016-11-30" version="1">MDQQIYDCASYDIEEQLQDYGFSLNNYSGFTLPSIDPGASLKPEQRFTFNQDHQAVFGHVMNMVENQHTTEPKVIFLDGPGGTGKTYLSNALLDATRRNHGITLAVSASGTAALLLKGGKTAHSLFKIPLKCDIHTMCSFTSASPTAQLIRSAELILWDEASMISRDVLEAVDRSFKDVCKQINPALEDVPFGGRVVVFGGDFRQVLLVVPKASRADIAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MWX2</accession>
    <name>A0A1C7MWX2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Phosphotransferase</fullName>
            <ecNumber evidence="6">2.7.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">A0J61_11012</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>D-fructose + ATP = D-fructose 6-phosphate + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:16125"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:37721"/>
            <dbReference type="ChEBI" id="CHEBI:61527"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.1"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="5">
            <dbReference type="Rhea" id="RHEA:16126"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>a D-hexose + ATP = a D-hexose 6-phosphate + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:22740"/>
            <dbReference type="ChEBI" id="CHEBI:4194"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:229467"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.1"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="4">
            <dbReference type="Rhea" id="RHEA:22741"/>
        </physiologicalReaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose: step 1/4.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2">Carbohydrate metabolism; hexose metabolism.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the hexokinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.-" evidence="6"/>
    <dbReference type="EMBL" id="LUGH01001587">
        <property type="protein sequence ID" value="OBZ80939.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MWX2"/>
    <dbReference type="STRING" id="101091.A0A1C7MWX2"/>
    <dbReference type="InParanoid" id="A0A1C7MWX2"/>
    <dbReference type="OrthoDB" id="419537at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005536">
        <property type="term" value="F:D-glucose binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008865">
        <property type="term" value="F:fructokinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004340">
        <property type="term" value="F:glucokinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006006">
        <property type="term" value="P:glucose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006096">
        <property type="term" value="P:glycolytic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001678">
        <property type="term" value="P:intracellular glucose homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.1250">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001312">
        <property type="entry name" value="Hexokinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022672">
        <property type="entry name" value="Hexokinase_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19443">
        <property type="entry name" value="HEXOKINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19443:SF16">
        <property type="entry name" value="HEXOKINASE TYPE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00349">
        <property type="entry name" value="Hexokinase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 6" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="6" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Hexokinase N-terminal" evidence="8">
        <location>
            <begin position="23"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="118"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004888"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00044613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00047905"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU362007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00349"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OBZ80939.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="118" mass="13456" checksum="07862C923589323A" modified="2016-11-30" version="1" fragment="single">MSQPRKSFSSGPATGTDAQMEAIDDLRQHFKLTDEELKHFRDSLRKEIDHGLQSHDSHMAMLPSWVFKHPTGQETGEYLGLELSNSNIRMYLVTLHGQGRITTRQQKIVVHDNLKKGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MWY5</accession>
    <name>A0A1C7MWY5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Methyltransferase-like protein 25</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">METTL25</name>
        <name evidence="1" type="ORF">A0J61_10615</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001271">
        <property type="protein sequence ID" value="OBZ81337.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MWY5"/>
    <dbReference type="STRING" id="101091.A0A1C7MWY5"/>
    <dbReference type="InParanoid" id="A0A1C7MWY5"/>
    <dbReference type="OrthoDB" id="10258156at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052220">
        <property type="entry name" value="METTL25"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12496">
        <property type="entry name" value="CGI-41 METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12496:SF0">
        <property type="entry name" value="METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ81337.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="210" mass="23808" checksum="375650D0371D976D" modified="2016-11-30" version="1">MMIRLFSTSSDFTCFVNVGCCYHFLTEQHPSAGFPLSQAVQQSGLQLGPTPKMLSCQAPARWEDQLEETLMAYEHHFFRALLQAIMVKKGLTDASKAPVIGRLNKKKDFTCFSVYVQAALKRLDLPQTTIPAEEAEAYYDSYKARGVDKQIAIVWTLRVLLGPVLESLILMDRWLYLDQTIPDSPTKNIWMWPLFDPVSSPRNMVIAATK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-06-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MWZ2</accession>
    <name>A0A1C7MWZ2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_10628</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001277">
        <property type="protein sequence ID" value="OBZ81323.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MWZ2"/>
    <dbReference type="InParanoid" id="A0A1C7MWZ2"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ81323.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="95" mass="11125" checksum="E5C9ED9DB1DF3F0B" modified="2016-11-30" version="1">MSSNNNNNNKRYLAALTKAIIKNPRKPSKKELMETKGELLAKQNEEKFAKKLKERQEQERLARQIRLTQNQFDGYNDMGIDSNAEWVDGDRLRKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-06-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MX44</accession>
    <name>A0A1C7MX44_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_10935</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001524">
        <property type="protein sequence ID" value="OBZ81016.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MX44"/>
    <dbReference type="InParanoid" id="A0A1C7MX44"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ81016.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="158" mass="18422" checksum="5F995923CBB17740" modified="2016-11-30" version="1">MCQALFTEEVKYDVTVIPESNKVVLTNFVNDSVEHLWPFDDNQNINLLYGWRLSSDRRYLIMAGLFDRRNVYIKVWDFWIKRYVYPERVGVDLVFSIKPFIVLQHEDTAATADCIGKMHCLARVQYKSNTTILDLSLNSGKQDVNKTSVSPKEEFFSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MYB1</accession>
    <name>A0A1C7MYB1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Phosphatidylglycerol/phosphatidylinositol transfer protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_10159</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001055">
        <property type="protein sequence ID" value="OBZ81792.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MYB1"/>
    <dbReference type="InParanoid" id="A0A1C7MYB1"/>
    <dbReference type="OrthoDB" id="6409159at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.770">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003172">
        <property type="entry name" value="ML_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02221">
        <property type="entry name" value="E1_DerP2_DerF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="E set domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MD-2-related lipid-recognition" evidence="2">
        <location>
            <begin position="7"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00016056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ81792.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="81" mass="8975" checksum="E3BB4A8C9A424364" modified="2016-11-30" version="1" fragment="single">VDIDLSIMGMIKIKKQLDLCSVLDSDVMGHQTCPLLAGDLQLDATAFIPKELPKLPLEGDIRITDQDGNRVTCIHLNFKLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MYE8</accession>
    <name>A0A1C7MYE8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_10140</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001049">
        <property type="protein sequence ID" value="OBZ81811.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MYE8"/>
    <dbReference type="InParanoid" id="A0A1C7MYE8"/>
    <dbReference type="OrthoDB" id="2295236at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ81811.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="233" mass="27130" checksum="AC764D0D6677A481" modified="2016-11-30" version="1">MCIPMGVKMSPSIHLNRIRAPFLYLFYNHYLSSSSFFILNMSNYFQNTAIKDLCLNKFDVAYKKEHVGCSKVVAHEKFADFLNDLTERDDLTEAEKKKVDSLKQQLKQCKSDPENTSIWSKKITRYLNGNGIKQSIMYDNSSKWVEADFDVSKALMSYRDKAVQSAEASRLLSDSQFLSLNFVFLFDRFAKIEYDLPEEVVSRLKKEMKAKRVDINKCLLSWSFEVVQKIGFR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MYM6</accession>
    <name>A0A1C7MYM6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">THO complex subunit 7</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">thoc7</name>
        <name evidence="5" type="ORF">A0J61_10061</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001018">
        <property type="protein sequence ID" value="OBZ81891.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MYM6"/>
    <dbReference type="STRING" id="101091.A0A1C7MYM6"/>
    <dbReference type="InParanoid" id="A0A1C7MYM6"/>
    <dbReference type="OrthoDB" id="205166at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000445">
        <property type="term" value="C:THO complex part of transcription export complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008501">
        <property type="entry name" value="THOC7/Mft1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05615">
        <property type="entry name" value="THOC7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="157"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="86"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="159"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="171"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="210"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OBZ81891.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="219" mass="25422" checksum="B4B5D3F9AAACE44E" modified="2016-11-30" version="1" fragment="single">HCRLEGLLVLLLGYQTNLERVPSIQAANTKDIQDYQQTVDETAIIQSQAGADIAVFKAELVEAQQARDQKLEYDRVARDIMHYETRDTYHESIQALERDIQLLQLEKENKQKAFESRKTNLSQLVNSLKDLQATVEQERSVVTEDQKRLMDMERGYISSDDEGDMGLSDDEGQHHDSAEQEEKADDHVTSRFKERNNEEDEDDHHRHHEEEDEEEGIVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MYX3</accession>
    <name>A0A1C7MYX3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Endonuclease/exonuclease/phosphatase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_10345</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001127">
        <property type="protein sequence ID" value="OBZ81606.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MYX3"/>
    <dbReference type="STRING" id="101091.A0A1C7MYX3"/>
    <dbReference type="InParanoid" id="A0A1C7MYX3"/>
    <dbReference type="OrthoDB" id="2443300at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.10.10">
        <property type="entry name" value="Endonuclease/exonuclease/phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036691">
        <property type="entry name" value="Endo/exonu/phosph_ase_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56219">
        <property type="entry name" value="DNase I-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ81606.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="129" mass="14688" checksum="B9E991F91445676F" modified="2016-11-30" version="1">MFVPFFVMVVYVTASSGRARKASFNHLLDSLFIPSMDIDLVCLINAGDSNYSHLRANLLSSTSERWVSFLEERFVDILRTFGLHELLTFRRNTSTSSTIDYIFASSDFTSPLSRQIYRLSTLSGLTTHF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MZA3</accession>
    <name>A0A1C7MZA3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_09848</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000953">
        <property type="protein sequence ID" value="OBZ82102.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="InParanoid" id="A0A1C7MZA3"/>
    <dbReference type="OrthoDB" id="2299316at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd09917">
        <property type="entry name" value="F-box_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12937">
        <property type="entry name" value="F-box-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00256">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="1">
        <location>
            <begin position="1"/>
            <end position="48"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ82102.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="354" mass="41192" checksum="EA46C3BCCC1DD7BB" modified="2016-11-30" version="1">MAASEELPQEIWDQVFRHLSQKELLLAASTCRKWYTRLRRHFYTYIRLKNLEMSEDFVSTLAKDPSLGDSVTTLTIQSSDRVKFDEENRFYDTLSVLIQQTQLVHSIKISYRIKRVFFEILRSACNAGFLSYVQTLRTTQTTNHCLFWCPDEPFSKESFVPIAVETISDKEVVVNNPGSRLEVAEIDSIINQHPEASTLKLNFYRLTDFHNAINLAEPCFNITQLIVNTXWPTNALLVYICEKFVSLQHLELVQPYNNSYMDNFVPGMTISRFASYLSNMTYFKVALLKLKSDTDVESHFKNILDNAHTRTWTSRSGQTLFMMRPTIGGTVMIGHYRTFAGLQDFNYSWNKRFR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MZB4</accession>
    <name>A0A1C7MZB4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">6-phosphogluconolactonase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">pgl</name>
        <name evidence="2" type="ORF">A0J61_10191</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the cycloisomerase 2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001065">
        <property type="protein sequence ID" value="OBZ81759.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MZB4"/>
    <dbReference type="STRING" id="101091.A0A1C7MZB4"/>
    <dbReference type="InParanoid" id="A0A1C7MZB4"/>
    <dbReference type="OrthoDB" id="9972196at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017057">
        <property type="term" value="F:6-phosphogluconolactonase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050282">
        <property type="entry name" value="Cycloisomerase_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011048">
        <property type="entry name" value="Haem_d1_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019405">
        <property type="entry name" value="Lactonase_7-beta_prop"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30344:SF1">
        <property type="entry name" value="6-PHOSPHOGLUCONOLACTONASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30344">
        <property type="entry name" value="6-PHOSPHOGLUCONOLACTONASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10282">
        <property type="entry name" value="Lactonase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51004">
        <property type="entry name" value="C-terminal (heme d1) domain of cytochrome cd1-nitrite reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005564"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ81759.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="367" mass="40932" checksum="7E18DCC205CD456B" modified="2016-11-30" version="1">MSSSEYTVYVSGYTNEESKGIYQYTFDAEKGILTRKGLAVETVNPSFITMHKTGQHMYAVNEVGEYKGEKTGYVSAFIRDKTTGQLELVNEQPSGGEDPCHAVCDATGHYLFVANYSGGSTTAFPIESPGSPESRLSPYSSRIVHDDHFEATGGVPDRQEKPHVHSVDLDSIAQKYLFSSDLGSDLLVTYRFDKQSSDPLKIHSTFQFPKGAGPRHLKFAPNHNNFCYVITELSNDIYMLEFNFQEGKFNKVQEIHALPSDFKGENLGAEIDITPNGKFLYVSMRGYDAITIFEIDEWSGKLSLVGYQPTGGKHPRFFTFDPTGRFLLVGNRDTDNIVVFKIDQQTGALTQVSGVSHVQPTCIQFWN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MZJ2</accession>
    <name>A0A1C7MZJ2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_11408</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01002000">
        <property type="protein sequence ID" value="OBZ80544.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MZJ2"/>
    <dbReference type="STRING" id="101091.A0A1C7MZJ2"/>
    <dbReference type="InParanoid" id="A0A1C7MZJ2"/>
    <dbReference type="OrthoDB" id="2237231at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="239"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ80544.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="239" mass="27930" checksum="612E9E69B683B8A8" modified="2016-11-30" version="1" fragment="single">MIVLLRKNQLTDASCEAIMLFCNMVLCLTDEAFRFPRSATTFEGWCNSMRFFSASIKEYASCITCHAIHPYDTEDEKKQVQQQRYCLDSGIFSKPSICEEELIAPNQYGTIAPDRSFFNNSLIDTFRSFFLRYEFVESINEWKQRQTLPETLSDIYDGLVWKNFKLRETDDKPFVLQSDYNLMLTLNCDRFQAYKDGYSVGAIYLTMQNLPREVRNLRSNSILVCLINGPKEPKTYEMN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N1I8</accession>
    <name>A0A1C7N1I8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Carnitine O-acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">CRAT_1</name>
        <name evidence="7" type="ORF">A0J61_08991</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the carnitine/choline acetyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000750">
        <property type="protein sequence ID" value="OBZ82962.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N1I8"/>
    <dbReference type="STRING" id="101091.A0A1C7N1I8"/>
    <dbReference type="InParanoid" id="A0A1C7N1I8"/>
    <dbReference type="OrthoDB" id="240216at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016746">
        <property type="term" value="F:acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.10">
        <property type="entry name" value="Chloramphenicol acetyltransferase-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.70">
        <property type="entry name" value="Choline/Carnitine o-acyltransferase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000542">
        <property type="entry name" value="Carn_acyl_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023213">
        <property type="entry name" value="CAT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039551">
        <property type="entry name" value="Cho/carn_acyl_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042231">
        <property type="entry name" value="Cho/carn_acyl_trans_2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22589">
        <property type="entry name" value="CARNITINE O-ACYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22589:SF107">
        <property type="entry name" value="CHOLINE_CARNITINE ACYLTRANSFERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00755">
        <property type="entry name" value="Carn_acyltransf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52777">
        <property type="entry name" value="CoA-dependent acyltransferases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00440">
        <property type="entry name" value="ACYLTRANSF_C_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5 7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Choline/carnitine acyltransferase" evidence="6">
        <location>
            <begin position="17"/>
            <end position="606"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="4">
        <location>
            <position position="323"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005232"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR600542-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OBZ82962.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="625" mass="71857" checksum="054DF8D7664FABB7" modified="2016-11-30" version="1">MSPQASTFSQQQTLPRLPIPSLEETCTLYLKSIMPLQTPEEHARTKSIVEEFCSNPLSRSLQQRLIDLDRASPNNWLEDNFWLRKEWREPLMVNSNWYILGQKDINHPKQLIANRGIQPSRLFSHFQIKRAAHMIRRGLEYKEFIDTETLPIERLKVTRIPLLHCDALVQANTKDVHHIIVLVRDQVYQLHVYKEIQAGFWILLSTEEIESALLSLIRDLEEMKDPSSPIPLLTSLHRDKWAMARNHLLTINHQTHRDNLKIIEDALFAVALDDHSNGIDYSSWTKTAFCGHQGLGHGHNRWFDKSLTLVVENNGMCAISGEHSPVDAMIVSWAFDYMLKDPVPGEHTHQFVHPSHRSNRSGQFRPLKFDTDITLDKFIDEANTDARKVATFSDSNVLLFDDYGTDWIKKIGRVPPDAFYQMVLQLAYYRAHHRVTATYETAATRKYLRGRTETIRTLSVETREFVEGFDRSDLSKKGKYDLLVKAAAAHRLYTQLASDGRGCDRHLLALRLLNADHTEFNQQGELVSVPLHSIFTDPIHDESQHWRLSTSSLHAGIRLMGTGFGTVYHDGYGINYMAAPDLVKFGIECKHVPETLSSNEFIDVIRQVLKDLQQLCQEVQNQSKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N253</accession>
    <name>A0A1C7N253_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Ral GTPase-activating protein subunit alpha-2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">Ralgapa2</name>
        <name evidence="4" type="ORF">A0J61_08880</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000728">
        <property type="protein sequence ID" value="OBZ83068.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N253"/>
    <dbReference type="STRING" id="101091.A0A1C7N253"/>
    <dbReference type="InParanoid" id="A0A1C7N253"/>
    <dbReference type="OrthoDB" id="1749473at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051056">
        <property type="term" value="P:regulation of small GTPase mediated signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11210">
        <property type="entry name" value="Rap/Ran-GAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039930">
        <property type="entry name" value="RALGAPB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035974">
        <property type="entry name" value="Rap/Ran-GAP_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000331">
        <property type="entry name" value="Rap/Ran_GAP_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21344">
        <property type="entry name" value="RAL GTPASE-ACTIVATING PROTEIN SUBUNIT BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21344:SF1">
        <property type="entry name" value="RAL GTPASE-ACTIVATING PROTEIN SUBUNIT BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02145">
        <property type="entry name" value="Rap_GAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111347">
        <property type="entry name" value="Rap/Ran-GAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50085">
        <property type="entry name" value="RAPGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0343">GTPase activation</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rap-GAP" evidence="3">
        <location>
            <begin position="457"/>
            <end position="700"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="144"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="188"/>
            <end position="199"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022468"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OBZ83068.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="723" mass="82403" checksum="F715EF55844775D0" modified="2016-11-30" version="1">MRYILHLINVYVIEDVPFCPGLVGTVVKLIQEKILTMQLPADVTLVAFDVLMDFVDLYDFVKRDSKNVARELVLALSRYVDTLINAGKLAQTYPLIVQAYDCMIKWILISQWIIDDRDCYKAVIATLSKGITIFEREDAVSTTSAEPVNVEKKKRRETGFPPTKQLFQLPPRGNKSHQQDHSNQQPASSTSNPNSRNSSAVRKKEEVAVRMAAEYCMSQLVNHLGQFVAFSKQETIDDTKQLKELLASERETISSSIRFFLIDKRTILTLIDNTKKSTEDKTLLNSIPSIVLVIRDTTGRYVWSMEAKYKEDVLKKIQSNDQQQQQQLVAASTFLKPPTEAKKMQKPVTVPTATAVNEKELPTLDKVFVPGSDSWRQWDAVKSLMEQQIDPDHALTNNSKSESRFLHSYQVSPTCSNVDADSSRAFRLFLSQIGFLLPQNRHHITPLHSNETLIAEMEKLDRLNERDCISISAYYATSGNVSWKEIVETPPALSQQFLQFINCLGWPIDLQDHKGYKGKLDKTLCDKIPYHSDRTVEFVVNVPYFLKEPKKEMGSEDEVPKTISSIHQDVSSDDHVCVIWIEDLSEYKRLAKLIKISSAPQSRAMVYIFINPLKHSADSLYWIRILIPSFDTTPQALLASQRLYENALIFGPLVDGIVVSRHALGSMVRSTAISAHQACRVVTDTYTRPYVIRKEYIEEMAHRHRVKLPLSEFYTDIFTEKAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N2Z9</accession>
    <name>A0A1C7N2Z9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_08940</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000740">
        <property type="protein sequence ID" value="OBZ83009.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N2Z9"/>
    <dbReference type="STRING" id="101091.A0A1C7N2Z9"/>
    <dbReference type="InParanoid" id="A0A1C7N2Z9"/>
    <dbReference type="OrthoDB" id="303107at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031213">
        <property type="term" value="C:RSF complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028938">
        <property type="entry name" value="Rsf1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14296:SF3">
        <property type="entry name" value="DIKAR, ISOFORM F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14296">
        <property type="entry name" value="REMODELING AND SPACING FACTOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="318"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="16"/>
            <end position="33"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ83009.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="513" mass="60057" checksum="F69389E0EAC02E31" modified="2016-11-30" version="1">MPSKNSSVNNKKMPKKSNEAKAVKSQEKKDKPEINVTSKSSPEEILHASWSFISAYQFFHMFRAYFKLPASFSIESLEQALLYGEQLNESAQTTRESSISSEISVSTEQPSKTLAEFMTKIICPLLSTRQRQNTTLYNFDESLRQLFPDVSFFKLDILRKIDLLKKIEQAYMDLKDEDFVTYKNENFIPDDMRLEPLGTDSKGWTYWYFGGFRLYREIPIPQGKKGIDMLNSRDFTFELVCHSIESWHQTVKIFESTKSKGAAKELGVKICELALEIIGKMEAREAARLRNEAKLKKARELELVPRKRSRRLEVKFDEEAKRQKIEEEEKQREAFERIERRNRLNEEEKEKREMKIEEARLKNDLHTYLTQRMADKDITQDELASLRELRLGIFSTTTEQVRKEKMKGWVQLLENPVTAKINEQHVTFVGDSLPEAFDSILLRNTLKTYLSTLMTFRFETNLLHDIYKKLLLKNGYSNIEAFCTDLNLLFESIDEKDRNHALNLLLSVFPHAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N327</accession>
    <name>A0A1C7N327_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_10208</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001073">
        <property type="protein sequence ID" value="OBZ81744.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N327"/>
    <dbReference type="InParanoid" id="A0A1C7N327"/>
    <dbReference type="OrthoDB" id="2242308at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="75"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="128"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="263"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="96"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="268"/>
            <end position="278"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ81744.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="314" mass="36777" checksum="D81961458655C6A7" modified="2016-11-30" version="1">MTSLGHNEPDIMDIQDKIGYVDTGPIPSSLPSSQPIIVSNAHLTIKEPKPQRQVWMENKRPQPILVKKATPVTTLPEPKAPLASLKPTVSFTPSTKGKEKEGKSDELKDMMVSKLYELADMLKSMNMDQESVRPRPTASTSDPARFIRRKSVPSNKPPDLRRNLKSAESMFQHPQEPYYPHYYLPPTSQHYYPYYPEESEDGVDELDKVDDLHLEDEDQYYHAYYPYYPYPHFDYEEDPRLPRHRYGPRRKSLGNLYEEHYYPTLQRKSSKNNLRRRQPTLDPRYDYPPHTTAAPMTPRYRYPPYYSSPNGYYV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N3P5</accession>
    <name>A0A1C7N3P5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_08249</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000619">
        <property type="protein sequence ID" value="OBZ83701.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N3P5"/>
    <dbReference type="InParanoid" id="A0A1C7N3P5"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008889469" description="Secreted protein" evidence="2">
        <location>
            <begin position="25"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="32"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="34"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ83701.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="67" mass="7270" checksum="30E8913D8CD0354E" modified="2016-11-30" version="1" fragment="single">MHTLETFFGLVVAFLTGTRLVVVALEVAGAGAKVEVEPRSGPEKTEEEKEESIGEAKEKPRREAGEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N418</accession>
    <name>A0A1C7N418_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF6570 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_08133</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000599">
        <property type="protein sequence ID" value="OBZ83820.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N418"/>
    <dbReference type="STRING" id="101091.A0A1C7N418"/>
    <dbReference type="InParanoid" id="A0A1C7N418"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046700">
        <property type="entry name" value="DUF6570"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20209">
        <property type="entry name" value="DUF6570"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF6570" evidence="2">
        <location>
            <begin position="168"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="52"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF20209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ83820.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="410" mass="46699" checksum="DC13BDF0482E921D" modified="2016-11-30" version="1">MSEDITPRRSGRKRRANCDPDFEYNIPTSSADRTESAVENEGNTDNAAEESSIERLRRQNRERQRASRQRRRQNATQLSETQLEEVRTRNLESQRASRQRRRQHEGPTVVCVCCGGPWFSNQTKSVTIESLLSRNASQEFIDNVFKFNQQQESNIFYSNYSDDVKNLRTPRLCASNGFELPEIPEALSCLNRVEERLVSARHVFQSIYTVLGLRGQYKSKGGIVNVPVSVDKTMSCVPRSLTDSNAIEARLTRRLSQSNNYMAGNVRLEKIWTAARFLSQSAAYIKHNVRIRDSEEEYNLLSTLIAQNCELDQLVTLFSELAIDSDDTTDDLDNDFMWNINPDGQETMFADDMTAKIVQENDDIRIAPAEGSSPMWLLLDRDVESLAFPTLFGGSILDPKHKEHLSVAVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N4C7</accession>
    <name>A0A1C7N4C7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Propionyl-CoA carboxylase beta chain, mitochondrial</fullName>
            <ecNumber evidence="3">6.4.1.3</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Propanoyl-CoA:carbon dioxide ligase subunit beta</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="primary">PCCB</name>
        <name evidence="11" type="ORF">A0J61_07995</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>butanoyl-CoA + hydrogencarbonate + ATP = (2S)-ethylmalonyl-CoA + ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:59520"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17544"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57371"/>
            <dbReference type="ChEBI" id="CHEBI:60909"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="7">
            <dbReference type="Rhea" id="RHEA:59521"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>propanoyl-CoA + hydrogencarbonate + ATP = (S)-methylmalonyl-CoA + ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:23720"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17544"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57327"/>
            <dbReference type="ChEBI" id="CHEBI:57392"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.4.1.3"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="8">
            <dbReference type="Rhea" id="RHEA:23721"/>
        </physiologicalReaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Metabolic intermediate metabolism; propanoyl-CoA degradation; succinyl-CoA from propanoyl-CoA: step 1/3.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">The holoenzyme is a dodecamer composed of 6 PCCA/alpha subunits and 6 PCCB/beta subunits.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the AccD/PCCB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.4.1.3" evidence="3"/>
    <dbReference type="EMBL" id="LUGH01000578">
        <property type="protein sequence ID" value="OBZ83953.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N4C7"/>
    <dbReference type="InParanoid" id="A0A1C7N4C7"/>
    <dbReference type="OrthoDB" id="439921at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004658">
        <property type="term" value="F:propionyl-CoA carboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009062">
        <property type="term" value="P:fatty acid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.226.10:FF:000017">
        <property type="entry name" value="Propionyl-CoA carboxylase subunit beta 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.226.10:FF:000016">
        <property type="entry name" value="Propionyl-CoA carboxylase, beta subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.226.10">
        <property type="entry name" value="2-enoyl-CoA Hydratase, Chain A, domain 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051047">
        <property type="entry name" value="AccD/PCCB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034733">
        <property type="entry name" value="AcCoA_carboxyl_beta"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011763">
        <property type="entry name" value="COA_CT_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011762">
        <property type="entry name" value="COA_CT_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43842">
        <property type="entry name" value="PROPIONYL-COA CARBOXYLASE BETA CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43842:SF2">
        <property type="entry name" value="PROPIONYL-COA CARBOXYLASE BETA CHAIN, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01039">
        <property type="entry name" value="Carboxyl_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="ClpP/crotonase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50989">
        <property type="entry name" value="COA_CT_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50980">
        <property type="entry name" value="COA_CT_NTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CoA carboxyltransferase N-terminal" evidence="9">
        <location>
            <begin position="20"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="domain" description="CoA carboxyltransferase C-terminal" evidence="10">
        <location>
            <begin position="278"/>
            <end position="517"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005060"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013050"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00038567"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00041138"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00042797"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00048208"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00049495"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="OBZ83953.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="523" mass="57293" checksum="6B0A02EA99F3E696" modified="2016-11-30" version="1">MLTRSRLFSNKQLSLIPHQCFYSATAIEHKRHQSLLGGGKAKQDAQHAKGKLTARERLNLLLDKGSFREYDAFVEHACADFNVPHVTGDGIITGHGQIHGRPVFVYSQDFTVLGGTLSRTNANKILKVMDQAMMVGAPIIGLQDSGGARIQEGVDSLAGYADIFQKNVLASGVVPQLSLIMGPCAGGAVYSPALTDFTFMVQDTSYMFVTGPDVVRSVTDEHVSQEVLGGASTHTTKTGVAHYAYANDIEALEGMRHFLTYLPSSNRQPAPRQRCDDPVDRQDEALDTIVPLDSSKAYDMKEVIHRIVDVHSFHELASTFAKNILVGFARLNGQSVGIVANQPLVSSGALDMDASVKAARFIRFXDAFEIPLITLVDVPGFMPGTAQEHAGIIRHGAKLLYAYCEATVPKMTVITRKAYGGAYIVMSSKHLRGDYNVAWPSAEIAVMGASGAVEIVFKKHPDKASMREQYKEKFATPLFAAKKGYLDDIISPRETRTRLVEQLELLQHKKLMNPWKKHGSIPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N4G0</accession>
    <name>A0A1C7N4G0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_08033</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000584">
        <property type="protein sequence ID" value="OBZ83917.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N4G0"/>
    <dbReference type="InParanoid" id="A0A1C7N4G0"/>
    <dbReference type="OrthoDB" id="2277277at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="83"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="117"/>
            <end position="136"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ83917.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="142" mass="16430" checksum="2A2064134B1CB053" modified="2016-11-30" version="1">MLQKKNHQAIVPGAYPNEVTQKHRYINLVHRIKHWRQKEPLQKQENNQINVSFTVNNHYHYQQSEHHKPSIVQQIVVLPPAQVYGLMALVALFLIIVGFALVQVHRTISILQVVLESLEYIVLTSMSGLGSIVSWIKRGIFY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N4L3</accession>
    <name>A0A1C7N4L3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Putative mitochondrial carnitine O-acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">YAT1_0</name>
        <name evidence="8" type="ORF">A0J61_07912</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the carnitine/choline acetyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000565">
        <property type="protein sequence ID" value="OBZ84040.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N4L3"/>
    <dbReference type="STRING" id="101091.A0A1C7N4L3"/>
    <dbReference type="InParanoid" id="A0A1C7N4L3"/>
    <dbReference type="OrthoDB" id="240216at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004092">
        <property type="term" value="F:carnitine O-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009437">
        <property type="term" value="P:carnitine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.559.10:FF:000019">
        <property type="entry name" value="Carnitine acetyl transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.559.70:FF:000003">
        <property type="entry name" value="Carnitine acetyl transferase FacC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.10">
        <property type="entry name" value="Chloramphenicol acetyltransferase-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.70">
        <property type="entry name" value="Choline/Carnitine o-acyltransferase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000542">
        <property type="entry name" value="Carn_acyl_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023213">
        <property type="entry name" value="CAT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039551">
        <property type="entry name" value="Cho/carn_acyl_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042231">
        <property type="entry name" value="Cho/carn_acyl_trans_2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22589">
        <property type="entry name" value="CARNITINE O-ACYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22589:SF29">
        <property type="entry name" value="MITOCHONDRIAL CARNITINE O-ACETYLTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00755">
        <property type="entry name" value="Carn_acyltransf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52777">
        <property type="entry name" value="CoA-dependent acyltransferases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00439">
        <property type="entry name" value="ACYLTRANSF_C_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00440">
        <property type="entry name" value="ACYLTRANSF_C_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5 8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Choline/carnitine acyltransferase" evidence="7">
        <location>
            <begin position="41"/>
            <end position="628"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="664"/>
            <end position="699"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="672"/>
            <end position="694"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="4">
        <location>
            <position position="345"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005232"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR600542-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OBZ84040.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="711" mass="80743" checksum="3E69EEC3FEFD9CB4" modified="2016-11-30" version="1">MKNAIGLISPDSSPRDEKASLPINEPSGGETFKFQDKLPKLPIPELESTAQKYLSVLKPLQSPKEHEETTLAVQEFLNQEGPLLQAKLQTYATDKSSYIEEFWYDSYLRYTDPVVLNLNPFFLLEDDPTPLRNDQVVRTSSLIFSTVKFIEALRNKTLEPDVFRGTPLCMSQFSRLFGTARVPSQNGCYIAPADDARHIVVMARSQFYHFDVLDEHGNGLLKEKDIAANLKAILKDAANTPVEALSQHAMGVLTTENRLNWARLRDELNSDQTNADSLRVVDTALFIVCLDHEEPKDADELSTNMLCGTYRLVDGMQVGTCTNRWYDKLQIIVCKNGNAGINFEHTGVDGHTVLRFVSDIYTETILRFAKTINSQTKSIFHSYQHEQTHLNKQSIDINPRKIEWNLTESLRLGIRFAETRLSDLILQNEVKVLEFRKYGKYFITDMKMSPDAFVQMAFQAAYYGLYGKNECTYEPAMTKTFLHGRTEAIRSVSEESVHFVKTFYSKMATSHEKLQALRSALKHHSKLTKECSMGLGQDRHLYALDCLWERLYPDQKKPRIFTDGGWKTLNHTVISTSNCGNPALRLFGFGPVVSNGFGIGYIIKEDGIAFVASSKHRQTQRYLDTLKQYLTDVQGLLLKEKYPTGLSRRQRVLELQEAAEQANDGYSYFDNGDSQKTENSGNESDVSSMGSHSSIQRKKVGKRLVLHEMDM</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N4P4</accession>
    <name>A0A1C7N4P4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">dihydroorotase</fullName>
            <ecNumber evidence="3">3.5.2.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">PYR3</name>
        <name evidence="9" type="ORF">A0J61_07923</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Pyrimidine metabolism; UMP biosynthesis via de novo pathway; (S)-dihydroorotate from bicarbonate: step 3/3.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.5.2.3" evidence="3"/>
    <dbReference type="EMBL" id="LUGH01000567">
        <property type="protein sequence ID" value="OBZ84031.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N4P4"/>
    <dbReference type="FunCoup" id="A0A1C7N4P4">
        <property type="interactions" value="322"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N4P4"/>
    <dbReference type="InParanoid" id="A0A1C7N4P4"/>
    <dbReference type="OrthoDB" id="1670005at2759"/>
    <dbReference type="UniPathway" id="UPA00070">
        <property type="reaction ID" value="UER00117"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004151">
        <property type="term" value="F:dihydroorotase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006207">
        <property type="term" value="P:'de novo' pyrimidine nucleobase biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044205">
        <property type="term" value="P:'de novo' UMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.140:FF:000071">
        <property type="entry name" value="Dihydroorotase, homodimeric type, variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.140">
        <property type="entry name" value="Metal-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00219">
        <property type="entry name" value="PyrC_classII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006680">
        <property type="entry name" value="Amidohydro-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004721">
        <property type="entry name" value="DHOdimr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002195">
        <property type="entry name" value="Dihydroorotase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00856">
        <property type="entry name" value="pyrC_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43137">
        <property type="entry name" value="DIHYDROOROTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43137:SF1">
        <property type="entry name" value="DIHYDROOROTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04909">
        <property type="entry name" value="Amidohydro_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001237">
        <property type="entry name" value="DHOdimr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="Metallo-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00482">
        <property type="entry name" value="DIHYDROOROTASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00483">
        <property type="entry name" value="DIHYDROOROTASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0665">Pyrimidine biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Amidohydrolase-related" evidence="8">
        <location>
            <begin position="77"/>
            <end position="176"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005631"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012860"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF04909"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OBZ84031.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="355" mass="39627" checksum="931F40092D8E2B5B" modified="2016-11-30" version="1">MSVNTITLPSACDFHLHLRQGDMMRMVTPKVEEGGVSLAYIMPNLQPPIKNTEQALKYKSELEALAPNVTFYMTLYLSPELTVEEVRKASKAGIAGVKSYPRGVTTNSDSGIENYELYYPVFKAMEEEGLVLNLHGEIPSDASKDICVMNAEERFLPELEKIHHAFPNLKIVLEHATTKAAVDMVKRLGDNVGCTITVHHLQLIVDDWAGQAHHFCKPVAKFPHDRDALRDIVREGHPRFFLGTDSAPHPIATKEGPRSNAGVFTSPLVLPYLAKIFEEIDCLDKLENFACHFGRKFYGLSQKPGFEDKKVTLVKESNVVVPQGYQISSTDAELGVVVPFYANKDIGWKIVENFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N4T8</accession>
    <name>A0A1C7N4T8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">A0J61_07916</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000566">
        <property type="protein sequence ID" value="OBZ84037.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N4T8"/>
    <dbReference type="FunCoup" id="A0A1C7N4T8">
        <property type="interactions" value="96"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N4T8"/>
    <dbReference type="InParanoid" id="A0A1C7N4T8"/>
    <dbReference type="OrthoDB" id="2985014at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd17327">
        <property type="entry name" value="MFS_FEN2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000013">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000034">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791">
        <property type="entry name" value="PERMEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791:SF36">
        <property type="entry name" value="TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_6G08340)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="56"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="94"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="123"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="152"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="183"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="215"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="285"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="325"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="349"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="375"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="411"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="442"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="56"/>
            <end position="469"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OBZ84037.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="498" mass="55132" checksum="AB6EE1E922832C71" modified="2016-11-30" version="1">MTKKEPEAFTEYHTKDEVVVEYNDVENSLPYGDDPDFVPPTAEELKQVIRKLDLRIIPFLGLLYLCSFLDRVNIGNAKLAGIVTDLHISSTDYNLALSIFFVGYIIFEVPSNMILKKIGPSKWIPIVMISWGTVMAAMAACKNTAGLLASRFFLGITEAGLFPGVIFYLTLWYTRGEQATRVALFFACSTLAGAFGGVLAYGIMQMDGINGLRGWQWIFIIEAIPTLILSIAAYFFLPNFPENSKFINDREREIIIHRLRKDAGPSIETVFSWRQFRAAFTDYRVYVHSLIYICGSTPLYSLSLFLPSIIQGMGFTDLRAQAMSAPPYAIACVFTVLVAMHADKQRERGLHVAIPGAVGCIGYALLYALRHQGAVPMYIAACITVTGVFSHIPAMLSWFTNNIGGHTKRGAATAFIISIGNVGGAIGGQIYRAEDAPLYGKGNLACMCLMAGVTIISVLFKLSLMRENKRRSELSKEAFEQEAASQICDRHPGFRYMT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N5G8</accession>
    <name>A0A1C7N5G8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_07570</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000517">
        <property type="protein sequence ID" value="OBZ84385.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N5G8"/>
    <dbReference type="InParanoid" id="A0A1C7N5G8"/>
    <dbReference type="OrthoDB" id="2284024at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ84385.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="153" mass="17032" checksum="FEC1A46F5B536589" modified="2016-11-30" version="1">MSNQLNDSMNNTKPMTDAELEAQFVERNQNLKQTLNNIVDKIDTAATKTQDFLETNANQMSNNLQGNNLQSSQLVHNDRMTTMAVGTGNFDNGLYKTAHGGGEDNIDMSNNMLDRKMMNSIRQDIQAMHSSDPEVFEGVATKMDETFGHNALV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N5R2</accession>
    <name>A0A1C7N5R2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_07596</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000521">
        <property type="protein sequence ID" value="OBZ84357.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N5R2"/>
    <dbReference type="InParanoid" id="A0A1C7N5R2"/>
    <dbReference type="OrthoDB" id="2210181at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ84357.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="183" mass="21578" checksum="6B6060DAEF3638DB" modified="2016-11-30" version="1">MTQLVESNGYFTMDTGLADSFAKWSRVLQAWSPPQKKRRAVIVLDSKEEEELKKQKLLNRRAIYIPPPIIHDGPKDQWQKWSLYRATHQKLRRNPLPLLESIHLRKMLTTLQKDQSMPHHLQVSGQDEEEDDNVPLGTLMKSNQMRSIQPPTKAYDPIYTSKRAPQYPYHFQYSPHLFPLRFN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N5W4</accession>
    <name>A0A1C7N5W4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative UDP-arabinose 4-epimerase 4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_09213</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000799">
        <property type="protein sequence ID" value="OBZ82734.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N5W4"/>
    <dbReference type="STRING" id="101091.A0A1C7N5W4"/>
    <dbReference type="InParanoid" id="A0A1C7N5W4"/>
    <dbReference type="OrthoDB" id="16464at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd08946">
        <property type="entry name" value="SDR_e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001509">
        <property type="entry name" value="Epimerase_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050177">
        <property type="entry name" value="Lipid_A_modif_metabolic_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43245">
        <property type="entry name" value="BIFUNCTIONAL POLYMYXIN RESISTANCE PROTEIN ARNA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43245:SF11">
        <property type="entry name" value="LD23561P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01370">
        <property type="entry name" value="Epimerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD-dependent epimerase/dehydratase" evidence="1">
        <location>
            <begin position="8"/>
            <end position="239"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ82734.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="376" mass="42428" checksum="12F7539672933571" modified="2016-11-30" version="1">MVQGKPNVLILGGVGFVGRNFVHYLLANELVGEIRVADKMLPQTAYLSETFQKDFSRVEFKQANLINQASIAACFDRQDGNQFDYVFNFAAETKYSQVPEIYQERIFNLSVNCAKEAAKRKVKVFIEMSTAEVYDSDQGASTETSKISPWTVIGKHKYKAEEELKKIEGLNLIILRPAVIYGPGANLGLTPRLIIGRIYKYLNEEMKLLWSKDLKLSTVHAHDVSRACWHLAQWYNNNNIGASGKVPTFNLADKQNTDQETINKQLQSIFNIKTGYHGTVVSTFAKLNKDAVIEAVNEKHLAPWAELVHKSGISVTPLSPYLDEELLYNNALSVDGSKIENETGFSYEVPLLTKEKLIEIIDEYKALNVWPRDDVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N645</accession>
    <name>A0A1C7N645_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_07463</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000503">
        <property type="protein sequence ID" value="OBZ84488.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N645"/>
    <dbReference type="InParanoid" id="A0A1C7N645"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="31"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="32"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="64"/>
            <end position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ84488.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="139" mass="15892" checksum="B0C92EFB5CFA3DAA" modified="2016-11-30" version="1">MKMTAEEKNFLARNFKRKALNAGVEVCMTDAIWEEDEEKDEEKDEEKDEEKDEDALVLAGSKRKASDVAESTRSKSRSSTKSVGIAPFLSLLPPLNNELMLSEKWMVDNMNVSAELMAIKNQCISKHYKNEKMKPIEYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N6Q2</accession>
    <name>A0A1C7N6Q2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Aminotransferase class V domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_07158</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000468">
        <property type="protein sequence ID" value="OBZ84790.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N6Q2"/>
    <dbReference type="FunCoup" id="A0A1C7N6Q2">
        <property type="interactions" value="14"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N6Q2"/>
    <dbReference type="InParanoid" id="A0A1C7N6Q2"/>
    <dbReference type="OrthoDB" id="5978656at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000192">
        <property type="entry name" value="Aminotrans_V_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43092:SF2">
        <property type="entry name" value="HERCYNYLCYSTEINE SULFOXIDE LYASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43092">
        <property type="entry name" value="L-CYSTEINE DESULFHYDRASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00266">
        <property type="entry name" value="Aminotran_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aminotransferase class V" evidence="2">
        <location>
            <begin position="55"/>
            <end position="394"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ84790.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="407" mass="45649" checksum="2FD5A81951053873" modified="2016-11-30" version="1">MSKHAQFGKHLRSEFLIEPEFTPLNHGSYGALPKALLPIIQEFRMKAEASPDRWLKREVFPLIDRNKAAIAELIHADPNELVFVFNAMTGINTVARSLPLKAGDKVLYFNTAYNAVESTIQFINDFESLKLVKIDLAYPLSDHAILEQIKETIEYENSLQNGSIKVCFMDAITSVPGLLFPFEAVVKLVREYSILSLVDGAHAIGQIPLDLHAVDPDFFITNCHKWLYAPRGCAVLYVPLRNQHLVHPAIINASYQHHPQPGTNTFQLEFAWPGTTDFTNFLCVEAALAFRKSIGGEKAIMDYCHDLAVSGGQLAATILGTEVLENEEKTLTTALVNVRLPINPAKIQSDPTFIQLSVDELIYKHHCMASVFKHNGQWYARLSAQVYNDLSDFEYVAKALLDLCHQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N6Q3</accession>
    <name>A0A1C7N6Q3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_07260</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000481">
        <property type="protein sequence ID" value="OBZ84688.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N6Q3"/>
    <dbReference type="STRING" id="101091.A0A1C7N6Q3"/>
    <dbReference type="InParanoid" id="A0A1C7N6Q3"/>
    <dbReference type="OrthoDB" id="2013972at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ84688.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="121" mass="13657" checksum="AD4C87910FEEAD2B" modified="2016-11-30" version="1">MPAHQVGTLLMTHGNFVDVHQHRVRIPIGWGGHLGEVHGQDYMSCVCSMHPKLVRDHIDLDYDRVMADGVKQCALNQSHINWFVCYGQKPAVTPCTNPSEQKVLWDATTAHDEVISCYCEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N6X9</accession>
    <name>A0A1C7N6X9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Spindle pole body-associated protein sad1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">sad1</name>
        <name evidence="9" type="ORF">A0J61_07070</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000459">
        <property type="protein sequence ID" value="OBZ84883.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N6X9"/>
    <dbReference type="InParanoid" id="A0A1C7N6X9"/>
    <dbReference type="OrthoDB" id="342281at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034993">
        <property type="term" value="C:meiotic nuclear membrane microtubule tethering complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043495">
        <property type="term" value="F:protein-membrane adaptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.260">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045119">
        <property type="entry name" value="SUN1-5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012919">
        <property type="entry name" value="SUN_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12911:SF8">
        <property type="entry name" value="KLAROID PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12911">
        <property type="entry name" value="SAD1/UNC-84-LIKE PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07738">
        <property type="entry name" value="Sad1_UNC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51469">
        <property type="entry name" value="SUN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="140"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="172"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="215"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="domain" description="SUN" evidence="8">
        <location>
            <begin position="467"/>
            <end position="631"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="68"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="279"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="22"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="88"/>
            <end position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51469"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OBZ84883.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="634" mass="73299" checksum="5E769F91B10BEFB1" modified="2016-11-30" version="1">MASPFRSRTPNPKRDEARWRSQRNPLNNLHGSIPNTPPRSFLTEYDDNEEDCLDIRQIDHDAIINDLEIKTQDPGSSHQARDPLFERQEEEEEEDDFGEYGEVEWLVNNPAAESRQRILAHSRQQPPAERRENQSWLQHILTYVVEGWIGKMIMKPVVFVLFMLFWIIKEPIIRVITFLTMIVSAVLVDPIVYLSSCFSRSEQQWMPAIETRHKIAHLLTVTMLTCGALYYLFTQPSRALEWIQQQQQSISFIPSSTASFFNIPPAVESTHSSDIFRRLAQVENQVGRLKKNTDQKLNRLSEQAKQFDQTHQKIWSAIDQQKTQLALVEKKISQEIHHAMANQLPDMLLVHTDQNGKMTPSPQFYQYLKDNLSWSSFLKHNEAAISDYMRGEMTAYLEQQKKEGAIVSKERFMKLLASDLSQQMNHQQTKQQEGVQQADLDQLVERAIQRYHQDLLNTPDFALYSRGAFILHGRTSPTYIKISSWMQMSXRMLGLPPLHSQPENAIFPAIYAGQCWSMASQQGTLGIMLSQRIYIQSVTIEHPTRDVLLDSIDSAPQSIEFYGIDHYTPFSGDLVLLGKGYYDINKNQSLQTFDIYMPTRSFQAVVVKVRTNWGNPNHTDLYRVRFHGIPAIDN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N8B2</accession>
    <name>A0A1C7N8B2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">J domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_08363</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000636">
        <property type="protein sequence ID" value="OBZ83584.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N8B2"/>
    <dbReference type="STRING" id="101091.A0A1C7N8B2"/>
    <dbReference type="InParanoid" id="A0A1C7N8B2"/>
    <dbReference type="OrthoDB" id="552049at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44924">
        <property type="entry name" value="DNAJ SUBFAMILY A MEMBER 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44924:SF1">
        <property type="entry name" value="DNAJ SUBFAMILY A MEMBER 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00625">
        <property type="entry name" value="JDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="J" evidence="2">
        <location>
            <begin position="86"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="51"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="57"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="123"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ83584.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="123" mass="13940" checksum="E1CF7FCA798D52D5" modified="2016-11-30" version="1" fragment="single">MTKIFESRKPEPYIKTSCKKCITPIEFLPEGQPVGQAVSVKCWSCNQTETYTVTDPNSHKDNKSSTADKPKTSRKRGTDQKPLSTEYYDLLGVEVTADQDAIKKAYRKLAIRYHPDKNQNDPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N8H0</accession>
    <name>A0A1C7N8H0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">ABC1 family protein MCP2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_06567</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000402">
        <property type="protein sequence ID" value="OBZ85383.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N8H0"/>
    <dbReference type="STRING" id="101091.A0A1C7N8H0"/>
    <dbReference type="InParanoid" id="A0A1C7N8H0"/>
    <dbReference type="OrthoDB" id="427480at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055088">
        <property type="term" value="P:lipid homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007005">
        <property type="term" value="P:mitochondrion organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004147">
        <property type="entry name" value="ABC1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051130">
        <property type="entry name" value="Mito_struct-func_regulator"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43173:SF19">
        <property type="entry name" value="AARF DOMAIN-CONTAINING PROTEIN KINASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43173">
        <property type="entry name" value="ABC1 FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03109">
        <property type="entry name" value="ABC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="34"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="domain" description="ABC1 atypical kinase-like" evidence="2">
        <location>
            <begin position="144"/>
            <end position="302"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ85383.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="312" mass="35989" checksum="B337E40029513D93" modified="2016-11-30" version="1">MNTTIKTISTKPFLRQSVKRLYNQQKNRSNNRKLFLIGSTVCLSAAGFTWHESDAHHLTVAFQRVGVASQIGISVAADYKLTELKRYDTEQEKVLAKKQCHQRCAERVLVGLQKLGGIYVKLGQHVSAMTYILPAEWTDTLSVLQDRCDPSSREDIEQMFLEDYGLPIHEVFEEFDWKPLGVASLAQVHKARLAGDHAGSGDQDWVAVKFQHPRLDAYCRVDLQTVAFIIQSIKRIFPEFGFEWILQEMQESLPQEMDFEREAANAAQLRSNFSYQHQLHSTALIIPKVMWAKRRILCMECMYIYNEKRMND</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N932</accession>
    <name>A0A1C7N932_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Terminal uridylyltransferase 7</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">ZCCHC6</name>
        <name evidence="4" type="ORF">A0J61_06362</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000381">
        <property type="protein sequence ID" value="OBZ85590.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N932"/>
    <dbReference type="FunCoup" id="A0A1C7N932">
        <property type="interactions" value="194"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N932"/>
    <dbReference type="InParanoid" id="A0A1C7N932"/>
    <dbReference type="OrthoDB" id="2274644at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016779">
        <property type="term" value="F:nucleotidyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010605">
        <property type="term" value="P:negative regulation of macromolecule metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031123">
        <property type="term" value="P:RNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05402">
        <property type="entry name" value="NT_PAP_TUTase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1410.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.460.10">
        <property type="entry name" value="Beta Polymerase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054708">
        <property type="entry name" value="MTPAP-like_central"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043519">
        <property type="entry name" value="NT_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12271">
        <property type="entry name" value="POLY A POLYMERASE CID PAP -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12271:SF40">
        <property type="entry name" value="POLY(A) RNA POLYMERASE GLD2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22600">
        <property type="entry name" value="MTPAP-like_central"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81301">
        <property type="entry name" value="Nucleotidyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81631">
        <property type="entry name" value="PAP/OAS1 substrate-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Poly(A) RNA polymerase mitochondrial-like central palm" evidence="3">
        <location>
            <begin position="191"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="135"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="67"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="146"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="163"/>
            <end position="176"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF22600"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OBZ85590.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="559" mass="64384" checksum="529D80E67FBAAA6A" modified="2016-11-30" version="1">MNLYEYNTSFRAFQPIRADLAEKTGLKDLGNDFVFVVYRVDDAIKLRDFEKEALYASVPMPSLDDIYSDEEEEVEGKEQKMSKQQKEDQQLTEIKKTKITIETYQQELDELDDEVVKDKVVVKLIEATEKKEEQVVLEQQENLAADEQRSPTIKEDDKNQNDENNDNENNDNENQDDDEYCLEQEIIDLCKANMITRASIVDRLNHMLNEIWGQRGVYVSTFGSSLHGLGTDNANVDLCIVVPYNSEHTKHEIRILRLLPNSLFNMYCVSNYLNAIGMTNVEPISKATVPICRFTDPITKLNCNINTNDVLGIHSTKLIMQYMKLDVRVRPLLFAIRYLCKKKAIASARNGTMASYAYHLLALYFLIHVQNPPVLPNLQQLTDAECKSKRCHYKRATRPVEGFDVRYHDCVIIDNKETEDFAITYDLDEHSTLWPSTSTKGVGELLVEFLEYFSNRDNLFKTMSISSPLDKIEMQKAWEHHLIVFPDPFFKTRNVCATVTKIGGDIICKEFKQASDMLKSGKTLQQVLNHKDAVPRPVDPQSLNFKLSKQRRQMCILAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N9T3</accession>
    <name>A0A1C7N9T3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Programmed cell death protein 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">PDCD2</name>
        <name evidence="6" type="ORF">A0J61_07840</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000554">
        <property type="protein sequence ID" value="OBZ84114.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N9T3"/>
    <dbReference type="FunCoup" id="A0A1C7N9T3">
        <property type="interactions" value="382"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N9T3"/>
    <dbReference type="InParanoid" id="A0A1C7N9T3"/>
    <dbReference type="OrthoDB" id="443682at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.2220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007320">
        <property type="entry name" value="PDCD2_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002893">
        <property type="entry name" value="Znf_MYND"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12298">
        <property type="entry name" value="PCDC2 PROGRAMMED CELL DEATH PROTEIN 2 -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12298:SF4">
        <property type="entry name" value="PROGRAMMED CELL DEATH PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04194">
        <property type="entry name" value="PDCD2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01753">
        <property type="entry name" value="zf-MYND"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144232">
        <property type="entry name" value="HIT/MYND zinc finger-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01360">
        <property type="entry name" value="ZF_MYND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50865">
        <property type="entry name" value="ZF_MYND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="MYND-type" evidence="5">
        <location>
            <begin position="158"/>
            <end position="196"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OBZ84114.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="410" mass="46334" checksum="216EBEFBB8482FFD" modified="2016-11-30" version="1">MSRNNDTNSDVSDLNPAKLTDDFDKYACQLGYAEDPEVPLTAETFPSKSGGKPVWLNPEHILTADQVTCGNCDEPMNLLLQLYTPEDQPADAFHRVVYVFCCKKGSCVKQDWTQSFRVFRSQLPRENPYYAPPSEDTDDQEDNTHGFVPKSFKAPSECVICGLGGSKLCGKCGEAAYCSREHQMSDWNMCRHKEFCNKSMLEEDQKIVASLRAARVFNEKEIISEPEGSDPDQEEEAHQAAFFKENNPEESNSDSKALVLASGDEVEEDTQVAVDDAFLQFQLKIQLNPDQVIRYDRVEYDMPKRDPLWVQANYKPASIPNCDRCHAPRTFEFQILSTLLNYLGVNHIAMDSLDWGSLYVYTCKENCELGNGVYAEEIIWKQDFSQDGMQLGPKEAEFLRRKQAAAAAAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NA17</accession>
    <name>A0A1C7NA17_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">tRNA-specific adenosine deaminase 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">adat1</name>
        <name evidence="2" type="ORF">A0J61_06487</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000393">
        <property type="protein sequence ID" value="OBZ85466.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NA17"/>
    <dbReference type="SMR" id="A0A1C7NA17"/>
    <dbReference type="FunCoup" id="A0A1C7NA17">
        <property type="interactions" value="476"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NA17"/>
    <dbReference type="InParanoid" id="A0A1C7NA17"/>
    <dbReference type="OrthoDB" id="10268011at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003726">
        <property type="term" value="F:double-stranded RNA adenosine deaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003725">
        <property type="term" value="F:double-stranded RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008251">
        <property type="term" value="F:tRNA-specific adenosine deaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006382">
        <property type="term" value="P:adenosine to inosine editing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006396">
        <property type="term" value="P:RNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002466">
        <property type="entry name" value="A_deamin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10910:SF62">
        <property type="entry name" value="AT07585P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10910">
        <property type="entry name" value="EUKARYOTE SPECIFIC DSRNA BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02137">
        <property type="entry name" value="A_deamin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00552">
        <property type="entry name" value="ADEAMc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50141">
        <property type="entry name" value="A_DEAMIN_EDITASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="A to I editase" evidence="1">
        <location>
            <begin position="1"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ85466.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="348" mass="39193" checksum="A2AD5E5117D9E2A3" modified="2016-11-30" version="1" fragment="single">TGLKCLPFSKLCKTGDVLNDSHAEIIARRGFIKNKKTKKGLLFLIHKVKCGSSMLTIRFICTLASHLTAKLPLIYEGGDASMSALADIQTPASLEVFESGKKRKRTVMNSFLEEHVYANKKKQKMTHDANVQRGRFGFDQLGILRTKPGRLDSEPSICMSCSDKLARWNVLGLQSALLSSLYSPVYLSSIVIGDMFDHSALERALYRRIQPILDLPSPYRLNQPKITSTHISFESSKSYLESLNRYKAIVSCATSISYVIGMSKAEVLVHGLKQGAPKNKPVNEKTRSSICKKSLFKKWQEITNNKTNSYLESKEQATTYQKAKICLLDQHFHNWVQTPAEYEDFTTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NAC7</accession>
    <name>A0A1C7NAC7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">DNA-directed RNA polymerase III subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">A0J61_05889</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Component of the RNA polymerase III (Pol III) complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 4">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 4">Belongs to the eukaryotic RPC7 RNA polymerase subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000332">
        <property type="protein sequence ID" value="OBZ86063.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NAC7"/>
    <dbReference type="FunCoup" id="A0A1C7NAC7">
        <property type="interactions" value="28"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NAC7"/>
    <dbReference type="InParanoid" id="A0A1C7NAC7"/>
    <dbReference type="OrthoDB" id="5377312at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005666">
        <property type="term" value="C:RNA polymerase III complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006383">
        <property type="term" value="P:transcription by RNA polymerase III"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024661">
        <property type="entry name" value="RNA_pol_III_Rpc31"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15367">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15367:SF2">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE III SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11705">
        <property type="entry name" value="RNA_pol_3_Rpc31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000777">
        <property type="entry name" value="RNA_polIII_C31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="152"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="174"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="203"/>
            <end position="218"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRNR" id="PIRNR000777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OBZ86063.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="218" mass="24541" checksum="435B710B450825FF" modified="2016-11-30" version="1">MSRGGRGGGFGGRGGGGGGAQSGAMQLVSFDLLKDLGSGNLFNVNTALFPEMDVPIPRKPTSNEIQQWKLRREYLTMVKDSPYHLTTPPPPPDIERYSDRYKVVAAKRSLREIETNFDFFPEELHVVLDPKRAKKKQKQRTAQDEYNQLAALLNVDEKGDGENDDEDGEKKDGEDEENEEEYEDEEEELIDDNDYAETYFDNGEGDDDDDGDNEDAYS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NAQ3</accession>
    <name>A0A1C7NAQ3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Vacuolar protein sorting-associated protein 21</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">VPS21_1</name>
        <name evidence="2" type="ORF">A0J61_05831</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000327">
        <property type="protein sequence ID" value="OBZ86110.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NAQ3"/>
    <dbReference type="STRING" id="101091.A0A1C7NAQ3"/>
    <dbReference type="InParanoid" id="A0A1C7NAQ3"/>
    <dbReference type="OrthoDB" id="63533at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01860">
        <property type="entry name" value="Rab5_related"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000808">
        <property type="entry name" value="Small GTP-binding protein, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001806">
        <property type="entry name" value="Small_GTPase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47978">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00071">
        <property type="entry name" value="Ras"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00449">
        <property type="entry name" value="RASTRNSFRMNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00175">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00176">
        <property type="entry name" value="RAN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00173">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00174">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51419">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51421">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51420">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ86110.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="224" mass="24921" checksum="B455E54FAE19DB6C" modified="2016-11-30" version="1">MSNTIDSSTERRPVPVKLVLLGESAVGKSSLVVRFVNREYSESREPTIGAAFLTQKCTVDDRTVKYEIWDTAGQERFHSLAPMYYRNAQAAIVMYDITKASTLEKAKGWVKELQRQANSQIVIALVGNKLDLVEDHPTEEDEQGSRQVTYEEASSYASEAGLLFFETSARTSFNVDNVFREIAKTIPHDYLVNNRNGLRSTTHGGNTTLDILRETGTQASGCAC</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NAU4</accession>
    <name>A0A1C7NAU4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="1">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">cki1_4</name>
        <name evidence="7" type="ORF">A0J61_05717</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="5">Belongs to the protein kinase superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="1"/>
    <dbReference type="EMBL" id="LUGH01000317">
        <property type="protein sequence ID" value="OBZ86235.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NAU4"/>
    <dbReference type="STRING" id="101091.A0A1C7NAU4"/>
    <dbReference type="InParanoid" id="A0A1C7NAU4"/>
    <dbReference type="OrthoDB" id="2264440at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:001123">
        <property type="entry name" value="CK1/CK1/CK1-D protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050235">
        <property type="entry name" value="CK1_Ser-Thr_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11909">
        <property type="entry name" value="CASEIN KINASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0418">Kinase</keyword>
    <keyword evidence="2 4 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="6">
        <location>
            <begin position="20"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="49"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU000304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OBZ86235.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="367" mass="42314" checksum="927B10875D29C5C5" modified="2016-11-30" version="1">MTTEAFSLERVIDSIVGGHFKVGKKLGEGSFGVIFEGTNLITSQQVAIKFEPKSSETPQLKDEYSAYKIMSGTIMDLLGPSLEELFDVCGRRFSIKTAAMLAIQMISRIQSIHERDLIYRDIKPDNFLIGLPGTDKENQLFVIDFGMAKLYRDKITKKHIPYQEQKNLSGTARYMSINTHLGREQSRRDDLEALGHVILYFLRGSLPWQGIKAATNRLKYEKIGETKQLTPIPSLCETFPNQLVKYMQYTRKLGFEETPNYDYMRKLFYEILRDIGEENDGIYDWVELSAKEANGWQDRIVARKMEKENNKPLMLEAPPLLPPHQQHEIINLTRTTEPMSMNRNQPNYDTSISKMDDCYPHIQTPHC</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NB48</accession>
    <name>A0A1C7NB48_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">GAR domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">A0J61_05756</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000321">
        <property type="protein sequence ID" value="OBZ86188.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NB48"/>
    <dbReference type="InParanoid" id="A0A1C7NB48"/>
    <dbReference type="OrthoDB" id="2250192at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005856">
        <property type="term" value="C:cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008017">
        <property type="term" value="F:microtubule binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.920.20">
        <property type="entry name" value="Gas2-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003108">
        <property type="entry name" value="GAR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036534">
        <property type="entry name" value="GAR_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02187">
        <property type="entry name" value="GAS2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00243">
        <property type="entry name" value="GAS2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143575">
        <property type="entry name" value="GAS2 domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46966">
        <property type="entry name" value="Spectrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51460">
        <property type="entry name" value="GAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GAR" evidence="6">
        <location>
            <begin position="566"/>
            <end position="640"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="468"/>
            <end position="563"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="183"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="493"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="524"/>
            <end position="554"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OBZ86188.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="766" mass="85059" checksum="C451344422A2DCEE" modified="2016-11-30" version="1">MSTVGNSGFASQDKASIDAMFKSIQSATVYSEKGAQSFAKQLSALNQKAAELAKEGYDAGSLQDPIKRIHENLNQLSNTIGIEKKQAMFVQKVFLHAKAVNDLKQWMDHCTHAIQQLPTDVCMNDEQELQAQLDTIKKNMADAAPSFKGFQTLRSRILTTKDGAPLDLCEISLDPNETNSILREREQAILKDYEAVKQQYEDACRLIEESKKNVEIARKFKSVLNQVGDMKDRVSAVRICKDSSDEDMTNRDLTAILSCPLSSIPGEHRLASAKAELDILDRDIDTHLIPSIQELDNMLDVLKRENGQDMFSDRREEITIAMEGLTGLMRTKRRAIAEAEKMEGFLTVVEELEVLLLAVGEVVARAAPENARIVDGSYSRTDLQALLIDLDTRYRYYEPKIHELFDEARMVSLRLLDDPRVEKCIRQLEKRWENLQAEVAAKKEDLMARIGPLADTFDSLEIEDNLLPQEKGSRKAASLMKRKSNPILRHPSPQASPSTRTGGSAASKAAKRHTTTPVPFAFSNTAARANARKATTSPTALKRLSGSSRLSQRSLRSKTPETYVADPQNDLDVAVGDIVNDSPYKIFVKMVPGEVGKYWFGEVNPKLAYCRILRSRMVMVRVGGGWVELSQFLRDHALLEGGNFVSGRHSRASMLPTPTGVTRDVFLNTASGRMTPHINRITSNNQGVVSIRGGAAANGTHTPLPTMRASKSTPYRGISQVPYTHGIKAGNKFLVALDGEGNRVEVKMTKATDKDTKFTTPRRLNI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NBI0</accession>
    <name>A0A1C7NBI0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">GTP-binding protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">Rraga_0</name>
        <name evidence="14" type="ORF">A0J61_05492</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">GTPase involved in activation of the TORC1 signaling pathway, which promotes growth and represses autophagy in nutrient-rich conditions.</text>
    </comment>
    <comment type="subunit">
        <text evidence="13">Component of the GSE complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Lysosome</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 13">Belongs to the GTR/RAG GTP-binding protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000297">
        <property type="protein sequence ID" value="OBZ86457.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NBI0"/>
    <dbReference type="FunCoup" id="A0A1C7NBI0">
        <property type="interactions" value="203"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NBI0"/>
    <dbReference type="InParanoid" id="A0A1C7NBI0"/>
    <dbReference type="OrthoDB" id="10020193at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000329">
        <property type="term" value="C:fungal-type vacuole membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990131">
        <property type="term" value="C:Gtr1-Gtr2 GTPase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009267">
        <property type="term" value="P:cellular response to starvation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010507">
        <property type="term" value="P:negative regulation of autophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1904263">
        <property type="term" value="P:positive regulation of TORC1 signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd11384">
        <property type="entry name" value="RagA_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.450.190:FF:000002">
        <property type="entry name" value="Ras-related GTP-binding protein A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000276">
        <property type="entry name" value="Ras-related GTP-binding protein A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.190">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006762">
        <property type="entry name" value="Gtr1_RagA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039397">
        <property type="entry name" value="RagA/B"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11259">
        <property type="entry name" value="RAS-RELATED GTP BINDING RAG/GTR YEAST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11259:SF1">
        <property type="entry name" value="RAS-RELATED GTP-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04670">
        <property type="entry name" value="Gtr1_RagA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="10 13" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1017">Isopeptide bond</keyword>
    <keyword evidence="12" id="KW-0458">Lysosome</keyword>
    <keyword evidence="11" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 13" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0832">Ubl conjugation</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004308"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007756"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022499"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022843"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023228"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU367014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="OBZ86457.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="301" mass="34850" checksum="5787C57AAC08AB7C" modified="2016-11-30" version="1">MKKKEKVLLMGKSGSGKTSMRSIIFSNYIARDTRRLGATIDVEHSNVKFLGNLVLNLWDCGGQEAFMENYFASQRDRIFKNVEVLIYVFDVESRDWEKDLHYYQSCLEAILANSKEARIFCLIHKMDLVPEHQRDQIFEQRVTELQKRSEPLTIQAFRTSIWDETLYAAWSKIVHCLIPNIRVLESHLDHFCRICDADEVVLFERTTFLVIATSATIPHQDHHRFEKISNIIKQFNLGCSRSQTRFKSMEIRGSSFTAFIDVLTNNTYAMIVMSDPNIQSAATLLNIAAAKKHFEKLEASR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NBI7</accession>
    <name>A0A1C7NBI7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Zinc finger protein 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">Zfp2</name>
        <name evidence="13" type="ORF">A0J61_05537</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the krueppel C2H2-type zinc-finger protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000301">
        <property type="protein sequence ID" value="OBZ86411.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NBI7"/>
    <dbReference type="STRING" id="101091.A0A1C7NBI7"/>
    <dbReference type="InParanoid" id="A0A1C7NBI7"/>
    <dbReference type="OrthoDB" id="654211at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000785">
        <property type="term" value="C:chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031519">
        <property type="term" value="C:PcG protein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005667">
        <property type="term" value="C:transcription regulator complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000125">
        <property type="entry name" value="Putative zinc finger protein 143"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:002343">
        <property type="entry name" value="Zinc finger protein 33A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000931">
        <property type="entry name" value="zinc finger protein 697"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000275">
        <property type="entry name" value="zinc finger protein 90 homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14003:SF20">
        <property type="entry name" value="FINGER DOMAIN PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_4G10380)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14003">
        <property type="entry name" value="TRANSCRIPTIONAL REPRESSOR PROTEIN YY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="9" id="KW-0804">Transcription</keyword>
    <keyword evidence="7" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <keyword evidence="5 11" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="12">
        <location>
            <begin position="21"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="12">
        <location>
            <begin position="51"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="12">
        <location>
            <begin position="81"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="12">
        <location>
            <begin position="111"/>
            <end position="137"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="OBZ86411.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="185" mass="21685" checksum="7DE14783E6321D84" modified="2016-11-30" version="1">MNISNLLNHAQYNFMNYERQYGCDWNECGKRFSRRSDLSRHKRIHTGERPFQCQWTNCHRQFIQRSALTVHLRTHTGERPHQCEVSNCQKSFSDSSSLARHRRTHTGIRPYRCECGKSFTRNTTLLRHRQTHQASISVRNESPEYKASRRSCSLPRTPSPSYQPLDSIATKTSGFLTTIKNELLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NBX9</accession>
    <name>A0A1C7NBX9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 5">Proline dehydrogenase</fullName>
            <ecNumber evidence="2 5">1.5.5.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">A0J61_05678</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Converts proline to delta-1-pyrroline-5-carboxylate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9 5">
            <text>L-proline + a quinone = (S)-1-pyrroline-5-carboxylate + a quinol + H(+)</text>
            <dbReference type="Rhea" id="RHEA:23784"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17388"/>
            <dbReference type="ChEBI" id="CHEBI:24646"/>
            <dbReference type="ChEBI" id="CHEBI:60039"/>
            <dbReference type="ChEBI" id="CHEBI:132124"/>
            <dbReference type="EC" id="1.5.5.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the proline oxidase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.5.5.2" evidence="2 5"/>
    <dbReference type="EMBL" id="LUGH01000314">
        <property type="protein sequence ID" value="OBZ86269.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NBX9"/>
    <dbReference type="FunCoup" id="A0A1C7NBX9">
        <property type="interactions" value="323"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NBX9"/>
    <dbReference type="InParanoid" id="A0A1C7NBX9"/>
    <dbReference type="OrthoDB" id="5464at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004657">
        <property type="term" value="F:proline dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010133">
        <property type="term" value="P:L-proline catabolic process to L-glutamate"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.220">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029041">
        <property type="entry name" value="FAD-linked_oxidoreductase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002872">
        <property type="entry name" value="Proline_DH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015659">
        <property type="entry name" value="Proline_oxidase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13914:SF0">
        <property type="entry name" value="PROLINE DEHYDROGENASE 1, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13914">
        <property type="entry name" value="PROLINE OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01619">
        <property type="entry name" value="Pro_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51730">
        <property type="entry name" value="FAD-linked oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0274">FAD</keyword>
    <keyword evidence="5" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="3 5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4 5" id="KW-0642">Proline metabolism</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Proline dehydrogenase" evidence="6">
        <location>
            <begin position="228"/>
            <end position="582"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005869"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023062"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU364054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01619"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OBZ86269.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="620" mass="69596" checksum="BEDBFA9A02DB16AB" modified="2016-11-30" version="1">MYRLASRTPLLRTSFNTAQRFTPLRPTTRAFRQFSTEHHVKPRVPFKTISASVLLTSAVYMYSQGVAQAEAAVAHAAVTGTTPSITLSELHDKSNRIAVEAKSTEELAMALFVYRLCAMSWLVDAAPHLIALAERLHLEAPVYWFVKQTFFRHFCGGETPEECVSSMDRLAQSGINCILDLSIEADLHMDASPVQDGQSKYFRDEQQADIVTKMIKTSIETAAQGCKENSMVAVKVTAFSPPELLLRLNQAMAALDTQFLAVQKNGHIDAQGVRHVIEKVVPPAESEEQAKQRESILTHLESKQATLDVIEFRKLFNLQGPGRDVWWKTANQDAKATFLTAEDLEAYDRMIGRLEEVASLAQSLKVGVMVDAEQSYFQDAIDHVAVNLQRKYNQRHQNHQQQPTIYNTYQMYTKSARGRLELDVELSKRENFTFAAKLVRGAYMVSERKRAEEMGYMSPICDTLEDTHASYNGGVKFLLNQLKEHQEATGETVTITNSPIVFMVASHNRDSVMLTIEEMEKSNVLPRSGVVQFGQLFGMQDQISYTLGRHGYAIYKYLPYGMINEVIPYLLRRAQENSSVLGGVAVERQLMWQEVKDRLTGRETAVSPDVSITTGTATSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NCC9</accession>
    <name>A0A1C7NCC9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">V-type proton ATPase subunit G</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">vma-10</name>
        <name evidence="7" type="ORF">A0J61_05300</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the V-ATPase G subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000283">
        <property type="protein sequence ID" value="OBZ86640.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NCC9"/>
    <dbReference type="FunCoup" id="A0A1C7NCC9">
        <property type="interactions" value="140"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NCC9"/>
    <dbReference type="InParanoid" id="A0A1C7NCC9"/>
    <dbReference type="OrthoDB" id="250802at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000221">
        <property type="term" value="C:vacuolar proton-transporting V-type ATPase, V1 domain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046961">
        <property type="term" value="F:proton-transporting ATPase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.5.2950:FF:000001">
        <property type="entry name" value="V-type proton ATPase subunit G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.2950">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005124">
        <property type="entry name" value="V-ATPase_G"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01147">
        <property type="entry name" value="V_ATP_synt_G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12713:SF11">
        <property type="entry name" value="V-TYPE PROTON ATPASE SUBUNIT G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12713">
        <property type="entry name" value="VACUOLAR ATP SYNTHASE SUBUNIT G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03179">
        <property type="entry name" value="V-ATPase_G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3 5" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="4 5" id="KW-0406">Ion transport</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0813">Transport</keyword>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="12"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010066"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU364019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OBZ86640.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="117" mass="13112" checksum="7F3E301424532D48" modified="2016-11-30" version="1">MSSANSQGINTLLDAEREAAKIVQKAKQYRVQRLKDARSEAAKEIEELKTQKNTEYQSFVAQHSGQSDQSLSKVDEETEAKIAEIRSAAEENKQVAIEKLIKAITNVEAKPHENYHA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NCE1</accession>
    <name>A0A1C7NCE1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_05314</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000283">
        <property type="protein sequence ID" value="OBZ86650.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NCE1"/>
    <dbReference type="InParanoid" id="A0A1C7NCE1"/>
    <dbReference type="OrthoDB" id="10595804at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="205"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="231"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="36"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="14"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ86650.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="353" mass="41269" checksum="C9D40A629994EBFB" modified="2016-11-30" version="1">MDSDELLENSQNGTDDDDDEEELQAEIEERVKKELEKMEESLKKADEGKKKGLAENPVDKSKDRFPPTEHKDILDHYLEALTKIAVSICKDQDEYTTRIQRFEQENIVVYQQFYFYLQDVKTYCKRQLDFFQSMQKQTDLIRAIDLNDNEEQANKGILVGYTLLQDAYRIMEPESVLPVPTEHFKQYPSEVTHIKKKLTANYRRSLFDTLFMLANGLVLMCLFSFFTARSITYYFIGSLLLFYTVAMVIQYRAFKKDRLISILDTLKTDMAALETASDTLKHWITDEITKLAKTQKSALFVFKKDPKDQENYGSIRIETDGAVMHIDIILSVHHAIYREVDNLSKRLECCILY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-06-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NCM0</accession>
    <name>A0A1C7NCM0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_05205</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000275">
        <property type="protein sequence ID" value="OBZ86748.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NCM0"/>
    <dbReference type="InParanoid" id="A0A1C7NCM0"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ86748.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="75" mass="8778" checksum="3929382B41AF4DB5" modified="2016-11-30" version="1">MRNQRVRIQSNWQTKKHQEKLNLVKIGSKRSRSEQDLMNVQVDQKQSFKNRAQNMLTSIPGFGHDKLESDSPNLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NCM5</accession>
    <name>A0A1C7NCM5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Homeobox protein 10</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">hbx10_4</name>
        <name evidence="4" type="ORF">A0J61_05117</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000268">
        <property type="protein sequence ID" value="OBZ86831.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NCM5"/>
    <dbReference type="STRING" id="101091.A0A1C7NCM5"/>
    <dbReference type="InParanoid" id="A0A1C7NCM5"/>
    <dbReference type="OrthoDB" id="6159439at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990837">
        <property type="term" value="F:sequence-specific double-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00086">
        <property type="entry name" value="homeodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001356">
        <property type="entry name" value="HD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052631">
        <property type="entry name" value="Paired_homeobox_Bicoid"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46255:SF3">
        <property type="entry name" value="HOMEOBOX DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46255">
        <property type="entry name" value="SHORT STATURE HOMEOBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00046">
        <property type="entry name" value="Homeodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00389">
        <property type="entry name" value="HOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50071">
        <property type="entry name" value="HOMEOBOX_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2 4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1 2 4" id="KW-0371">Homeobox</keyword>
    <keyword evidence="1 2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Homeobox" evidence="3">
        <location>
            <begin position="85"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="Homeobox" evidence="1">
        <location>
            <begin position="87"/>
            <end position="146"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU000682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OBZ86831.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="214" mass="24400" checksum="4F7B87A6C7F70212" modified="2016-11-30" version="1">MYSTSCTLPPLSNLLIYQPAKPMHRSPAFDINNLLSNDVSEHTDLPTASSSVASISNITIPTTTTHTMHHTTILDEADDKRQQRRNLKAKRKRASPNQLLVLNRIFSQTYFPSTEIRVELGKQLGMSPRTVQIWFQNKRQALRSRGRHAPAPTNCYLPPISPPRSPQSSYYYRQNHCQHHQEFNVSLPPLRLTQYNSPPSSVSFPSPNSMDYPF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NCS5</accession>
    <name>A0A1C7NCS5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">MOB-like protein phocein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">Mob4</name>
        <name evidence="2" type="ORF">A0J61_05385</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000289">
        <property type="protein sequence ID" value="OBZ86559.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NCS5"/>
    <dbReference type="STRING" id="101091.A0A1C7NCS5"/>
    <dbReference type="InParanoid" id="A0A1C7NCS5"/>
    <dbReference type="OrthoDB" id="10262609at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.140.30">
        <property type="entry name" value="MOB kinase activator"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005301">
        <property type="entry name" value="MOB_kinase_act_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036703">
        <property type="entry name" value="MOB_kinase_act_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22599">
        <property type="entry name" value="MPS ONE BINDER KINASE ACTIVATOR-LIKE MOB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03637">
        <property type="entry name" value="Mob1_phocein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01388">
        <property type="entry name" value="Mob1_phocein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101152">
        <property type="entry name" value="Mob1/phocein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <feature type="binding site" evidence="1">
        <location>
            <position position="87"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="92"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="163"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="168"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR605301-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ86559.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="242" mass="28173" checksum="847105E2B455998F" modified="2016-11-30" version="1">MTGSLRRLYPGKRLEDTFQWSFENLDALESSFNVQEYLQQLIRKDPSDTQHIIELPAGVDEEVWQYEHLRQVCLELSLLIVALEPECTRQNCPEMKADGWLYLCAAHPSTQSCPAIDYITHTLDGATILLNNSKYFPSRISVPEPSLKHFQSIARRLYRVFAHAYCHHREVYESFENETYLYTRFLKLAQTYHLVPPNLISISSQYEDSTSKETEDTIYSRNLSYNSSSILLSQKEDDDDDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7ND24</accession>
    <name>A0A1C7ND24_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 11">Ribonucleoside-diphosphate reductase</fullName>
            <ecNumber evidence="3 11">1.17.4.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">RNR1</name>
        <name evidence="13" type="ORF">A0J61_05086</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9 11">Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>a 2'-deoxyribonucleoside 5'-diphosphate + [thioredoxin]-disulfide + H2O = a ribonucleoside 5'-diphosphate + [thioredoxin]-dithiol</text>
            <dbReference type="Rhea" id="RHEA:23252"/>
            <dbReference type="Rhea" id="RHEA-COMP:10698"/>
            <dbReference type="Rhea" id="RHEA-COMP:10700"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:50058"/>
            <dbReference type="ChEBI" id="CHEBI:57930"/>
            <dbReference type="ChEBI" id="CHEBI:73316"/>
            <dbReference type="EC" id="1.17.4.1"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="2">Heterodimer of a large and a small subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 11">Belongs to the ribonucleoside diphosphate reductase large chain family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.17.4.1" evidence="3 11"/>
    <dbReference type="EMBL" id="LUGH01000265">
        <property type="protein sequence ID" value="OBZ86860.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7ND24"/>
    <dbReference type="STRING" id="101091.A0A1C7ND24"/>
    <dbReference type="InParanoid" id="A0A1C7ND24"/>
    <dbReference type="OrthoDB" id="3000483at2759"/>
    <dbReference type="UniPathway" id="UPA00326"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005971">
        <property type="term" value="C:ribonucleoside-diphosphate reductase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004748">
        <property type="term" value="F:ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009263">
        <property type="term" value="P:deoxyribonucleotide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01679">
        <property type="entry name" value="RNR_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.70.20:FF:000010">
        <property type="entry name" value="Ribonucleoside-diphosphate reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.70.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005144">
        <property type="entry name" value="ATP-cone_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013346">
        <property type="entry name" value="NrdE_NrdA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000788">
        <property type="entry name" value="RNR_lg_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013509">
        <property type="entry name" value="RNR_lsu_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008926">
        <property type="entry name" value="RNR_R1-su_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039718">
        <property type="entry name" value="Rrm1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02506">
        <property type="entry name" value="NrdE_NrdA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11573">
        <property type="entry name" value="RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE LARGE CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11573:SF6">
        <property type="entry name" value="RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE LARGE SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03477">
        <property type="entry name" value="ATP-cone"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02867">
        <property type="entry name" value="Ribonuc_red_lgC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00317">
        <property type="entry name" value="Ribonuc_red_lgN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01183">
        <property type="entry name" value="RIBORDTASEM1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51998">
        <property type="entry name" value="PFL-like glycyl radical enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48168">
        <property type="entry name" value="R1 subunit of ribonucleotide reductase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51161">
        <property type="entry name" value="ATP_CONE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00089">
        <property type="entry name" value="RIBORED_LARGE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0021">Allosteric enzyme</keyword>
    <keyword evidence="6 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8 11" id="KW-0215">Deoxyribonucleotide synthesis</keyword>
    <keyword evidence="5 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7 11" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ATP-cone" evidence="12">
        <location>
            <begin position="2"/>
            <end position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010406"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023116"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00024942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU003410"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="OBZ86860.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="799" mass="90565" checksum="04F09D3225B7B876" modified="2016-11-30" version="1">MMYVIKRDGSKENVHFDKITSRISKLCYGLNEEFVIPDQIAQKVVSGVYQGITTVELDNLAAETAAYMTTSHPDFAVLAARIVISNLQKETDSKFSQVIYKLYHHVHPKLNEPNPLISKELYDVVMVNADRIDQTIISDRDYDFSFFGFKTLERSYLFKINGKIVERPQYMIMRVALGIHGQDLESAFKTYDLMSSKYFTHATPTLFNAGTPKPQLSSCFLVQMKEDSIEGIYDTLTTCARISKAAGGVGVSFQKIRGSGSYIAGTNGTSNGIVPMLRVFNDTARFVTQGGGKRNGNFAMYLEPWHIDVFDFLELRKNQGADEVRARDLFLGLWVSDLFMERVEQNGQWSLFCPNEAPGLDQCYGDKFNALYTKYENEGKARKTIDAQKLWFAILESQIETGMPYMLYKDACNEKSNQKNLGTITSSNLCTEIIEYTSPDEVAVCNLASLALPKFVNVETKTFDFDKLHEVTKVVTRNLNRVIDVNYYPVEEAERSNMRHRPIGLGVQGLADAFILMGFPFDSPEARQLNRDIFERIYFAALEASCELAKEHGHYESYPGSPISQGLLQHDLWHVQGSDHLDWAALRRKIQQHGVRNSLLLAPMPTASTSQILGNTECFEPYTSNIYTRRVQSGEFQVVNQHLLNDLVKRGLWSDNLKNMMIAHGGSVQEIPTIPDDLKKLYKTVWEISQRTIIDMAADRGAFIDQSQSMNLFTAEPNYGKLTSMHFYAWKKGLKTGMYYLRTRPAVDAIKFTVDQLALKNMSLSEDKQTLTSEEEEQQRLAQLQCSIDNRDACLMCSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NDC2</accession>
    <name>A0A1C7NDC2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Putative peptide chain release factor C12orf65, mitochondrial</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">CL065</name>
        <name evidence="7" type="ORF">A0J61_04879</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the prokaryotic/mitochondrial release factor family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000249">
        <property type="protein sequence ID" value="OBZ87075.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NDC2"/>
    <dbReference type="FunCoup" id="A0A1C7NDC2">
        <property type="interactions" value="194"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NDC2"/>
    <dbReference type="InParanoid" id="A0A1C7NDC2"/>
    <dbReference type="OrthoDB" id="277888at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003747">
        <property type="term" value="F:translation release factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032543">
        <property type="term" value="P:mitochondrial translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052405">
        <property type="entry name" value="Mito_Transl_Release_Factor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000352">
        <property type="entry name" value="Pep_chain_release_fac_I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045853">
        <property type="entry name" value="Pep_chain_release_fac_I_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46203:SF1">
        <property type="entry name" value="MITOCHONDRIAL TRANSLATION RELEASE FACTOR IN RESCUE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46203">
        <property type="entry name" value="PROBABLE PEPTIDE CHAIN RELEASE FACTOR C12ORF65"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00472">
        <property type="entry name" value="RF-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75620">
        <property type="entry name" value="Release factor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="Prokaryotic-type class I peptide chain release factors" evidence="6">
        <location>
            <begin position="28"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="97"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="103"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="124"/>
            <end position="133"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00472"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OBZ87075.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="142" mass="16137" checksum="46267509808B68C5" modified="2016-11-30" version="1">MSFFRFLSRPFPTQPLLRSFTTRPTERKKIVLRDEDLVETFVKGSGPGGQCINKRSSCVDLRHIPTGIRVQCQQSRSLADNRGIARKLLREKLDELENGHLSKNGKKAAKIAKQKARRAKRAKEKYGKPKEEPNSAIPPPEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NDQ9</accession>
    <name>A0A1C7NDQ9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">EF-hand domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">A0J61_04733</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000238">
        <property type="protein sequence ID" value="OBZ87215.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NDQ9"/>
    <dbReference type="STRING" id="101091.A0A1C7NDQ9"/>
    <dbReference type="InParanoid" id="A0A1C7NDQ9"/>
    <dbReference type="OrthoDB" id="26525at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0106">Calcium</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="136"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="domain" description="F-box" evidence="3">
        <location>
            <begin position="1"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="4">
        <location>
            <begin position="215"/>
            <end position="250"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OBZ87215.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="311" mass="36761" checksum="6D79A49F90A02237" modified="2016-11-30" version="1">MQRLPENIITRIAYFSSIEDALALGSCSRHCYHSILDNEAFWRSKSLKEFGNIFRLYQIFITSTGLELPSDIADKFAKRPTDWHAYYVQKHTSFQKVDYDTLLDQCDREYMEAQRHLTTFQDDINYSVLTQVASKMFWILDTLPVYAGCYFILSYILYFMKRFEDALDILDMGRNADPSFTQFNELEREIIDSMQNEERKFTDVPLLINENLSPELIAVLLEIFHRFDKDKDNCLNFEELDRFVFSTNGQHPPHSFLQQFGQRFGSNEHGWLTKEGFLAFYLEQTLDDVHETRKDIRAHGYDCSRLKKKTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NER8</accession>
    <name>A0A1C7NER8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">DNA repair protein RAD51 homolog 3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">Rad51c</name>
        <name evidence="10" type="ORF">A0J61_04397</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000214">
        <property type="protein sequence ID" value="OBZ87558.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NER8"/>
    <dbReference type="STRING" id="101091.A0A1C7NER8"/>
    <dbReference type="InParanoid" id="A0A1C7NER8"/>
    <dbReference type="OrthoDB" id="5957327at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033063">
        <property type="term" value="C:Rad51B-Rad51C-Rad51D-XRCC2 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033065">
        <property type="term" value="C:Rad51C-XRCC3 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005657">
        <property type="term" value="C:replication fork"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140664">
        <property type="term" value="F:ATP-dependent DNA damage sensor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008821">
        <property type="term" value="F:crossover junction DNA endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000400">
        <property type="term" value="F:four-way junction DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000707">
        <property type="term" value="P:meiotic DNA recombinase assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007131">
        <property type="term" value="P:reciprocal meiotic recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd19492">
        <property type="entry name" value="Rad51C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052093">
        <property type="entry name" value="HR_Repair_Mediator"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013632">
        <property type="entry name" value="Rad51_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020588">
        <property type="entry name" value="RecA_ATP-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46239:SF1">
        <property type="entry name" value="DNA REPAIR PROTEIN RAD51 HOMOLOG 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46239">
        <property type="entry name" value="DNA REPAIR PROTEIN RAD51 HOMOLOG 3 RAD51C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08423">
        <property type="entry name" value="Rad51"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50162">
        <property type="entry name" value="RECA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0227">DNA damage</keyword>
    <keyword evidence="5" id="KW-0234">DNA repair</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RecA family profile 1" evidence="9">
        <location>
            <begin position="72"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="338"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="364"/>
            <end position="376"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00040674"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50162"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OBZ87558.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="455" mass="51298" checksum="43A52D05DCF8A1EB" modified="2016-11-30" version="1">MSISNAITLPSLLQKLQEGGYDDLDQIKDANLFELTEELSLNKEEVQFLIKACGKEPKVLKRSLGDIIAAEKRCSISTSSKSFNSLLGYGVPPFKITEVCGESGSGKSQICMQLAVNAQLPSELGGVQGECLYIDTEGSFQYSRIASMSKNHNTESILGGIHLFRVLDYTELLALVRQLPDILQHYPKVRLIIIDSIAYHFRVNVLDSRARTAILDYLAQALIEIANKNNLAIVVSNHVTIDGADATWTPSLGSSWGYWCANRLFLFRKREFRFGYLYKSVENEGSKPVQFCIKDEGIADPEESEEFLFTKQEEDAQEREERVNAVWNNLKANHIKKEEDRHPEQLFLPDDDVNSTDENIASNVDEKVEQNTEKDIQSSPDDTLVPPETETANHTNGLKRANSTDERDGQKKICLDKVATADNSDNNYVNDSDYWTSDVEEEIDMQFLNNVHSYF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-06-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NF20</accession>
    <name>A0A1C7NF20_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_04264</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000204">
        <property type="protein sequence ID" value="OBZ87695.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NF20"/>
    <dbReference type="InParanoid" id="A0A1C7NF20"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ87695.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="68" mass="7894" checksum="F613EE759093DE95" modified="2016-11-30" version="1">MIEEVVPYLEFFNKIATTEYNNKEDLRNDICQLGKEHNVVMSIKSSTSTSVNYICKHVGEKRIRSDRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NFJ3</accession>
    <name>A0A1C7NFJ3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="17">Nicotinamide-nucleotide adenylyltransferase</fullName>
            <ecNumber evidence="17">2.7.7.1</ecNumber>
            <ecNumber evidence="17">2.7.7.18</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="19" type="primary">NMA2</name>
        <name evidence="19" type="ORF">A0J61_04223</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="19 20" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19 20">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="16">Catalyzes the formation of NAD(+) from nicotinamide mononucleotide (NMN) and ATP. Can also use the deamidated form; nicotinic acid mononucleotide (NaMN) as substrate with the same efficiency. Can use triazofurin monophosphate (TrMP) as substrate. Can also use GTP and ITP as nucleotide donors. Also catalyzes the reverse reaction, i.e. the pyrophosphorolytic cleavage of NAD(+). For the pyrophosphorolytic activity, can use NAD(+), NADH, NaAD, nicotinic acid adenine dinucleotide phosphate (NHD), nicotinamide guanine dinucleotide (NGD) as substrates. Fails to cleave phosphorylated dinucleotides NADP(+), NADPH and NaADP(+). Protects against axonal degeneration following injury. May be involved in the maintenance of axonal integrity. Also functions as a stress-response chaperone protein that prevents toxic aggregation of proteins; this function may be independent of its NAD(+) synthesis activity.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="15 17">
            <text>beta-nicotinamide D-ribonucleotide + ATP + H(+) = diphosphate + NAD(+)</text>
            <dbReference type="Rhea" id="RHEA:21360"/>
            <dbReference type="ChEBI" id="CHEBI:14649"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="EC" id="2.7.7.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14 17">
            <text>nicotinate beta-D-ribonucleotide + ATP + H(+) = deamido-NAD(+) + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:22860"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57502"/>
            <dbReference type="ChEBI" id="CHEBI:58437"/>
            <dbReference type="EC" id="2.7.7.18"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3 17">Cofactor biosynthesis; NAD(+) biosynthesis; NAD(+) from nicotinamide D-ribonucleotide: step 1/1.</text>
    </comment>
    <comment type="pathway">
        <text evidence="4">Cofactor biosynthesis; NAD(+) biosynthesis; deamido-NAD(+) from nicotinate D-ribonucleotide: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Homotetramer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5 17">Belongs to the eukaryotic NMN adenylyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="19">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.1" evidence="17"/>
    <dbReference type="EC" id="2.7.7.18" evidence="17"/>
    <dbReference type="EMBL" id="LUGH01000201">
        <property type="protein sequence ID" value="OBZ87730.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NFJ3"/>
    <dbReference type="FunCoup" id="A0A1C7NFJ3">
        <property type="interactions" value="172"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NFJ3"/>
    <dbReference type="InParanoid" id="A0A1C7NFJ3"/>
    <dbReference type="OrthoDB" id="422187at2759"/>
    <dbReference type="UniPathway" id="UPA00253">
        <property type="reaction ID" value="UER00332"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000309">
        <property type="term" value="F:nicotinamide-nucleotide adenylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004515">
        <property type="term" value="F:nicotinate-nucleotide adenylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009435">
        <property type="term" value="P:NAD+ biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd09286">
        <property type="entry name" value="NMNAT_Eukarya"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.620:FF:000221">
        <property type="entry name" value="Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004821">
        <property type="entry name" value="Cyt_trans-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051182">
        <property type="entry name" value="Euk_NMN_adenylyltrnsfrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005248">
        <property type="entry name" value="NadD/NMNAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045094">
        <property type="entry name" value="NMNAT_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00482">
        <property type="entry name" value="nicotinate (nicotinamide) nucleotide adenylyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12039">
        <property type="entry name" value="NICOTINAMIDE MONONUCLEOTIDE ADENYLYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12039:SF0">
        <property type="entry name" value="NICOTINAMIDE-NUCLEOTIDE ADENYLYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01467">
        <property type="entry name" value="CTP_transf_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52374">
        <property type="entry name" value="Nucleotidylyl transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11 17" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="13" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="12 17" id="KW-0520">NAD</keyword>
    <keyword evidence="10 17" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9 17 19" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="7 17" id="KW-0662">Pyridine nucleotide biosynthesis</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 17 19" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Cytidyltransferase-like" evidence="18">
        <location>
            <begin position="40"/>
            <end position="211"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004658"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00007064"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00011881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00048721"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00049001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00093425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="RuleBase" id="RU362021"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="Pfam" id="PF01467"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="OBZ87730.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="242" mass="27829" checksum="E536E883F9D9B449" modified="2016-11-30" version="1">MQQEDNNTINSVPYELTPLSFNVPYEFPRRFLPTVMKEMAQDHFKERNEFELLTGYYSPVSDYYMKEGLAKAEHRVKMCQLAVETTSDWLMVDSWEARQTTYQRTAVVLDHFDHELNTIGGGILTSTGEKRKIRIMLLAGGDLIASFGHPGVWAPDDLHHIVGRYGSVIIERTGTDVYGFLLSHDILYQHRMNVTVIKQLIHNDISSTKIRLFVKRGMSIKYLLPNPVIDYIHAHGLYLPAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NFQ3</accession>
    <name>A0A1C7NFQ3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Heat shock protein 12A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">HSPA12A_1</name>
        <name evidence="4" type="ORF">A0J61_04142</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000196">
        <property type="protein sequence ID" value="OBZ87800.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NFQ3"/>
    <dbReference type="InParanoid" id="A0A1C7NFQ3"/>
    <dbReference type="OrthoDB" id="2963168at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd10229">
        <property type="entry name" value="ASKHA_NBD_HSP70_HSPA12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013126">
        <property type="entry name" value="Hsp_70_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14187">
        <property type="entry name" value="ALPHA KINASE/ELONGATION FACTOR 2 KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14187:SF5">
        <property type="entry name" value="HEAT SHOCK 70 KDA PROTEIN 12A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00012">
        <property type="entry name" value="HSP70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0346">Stress response</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="561"/>
            <end position="581"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="617"/>
            <end position="741"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="567"/>
            <end position="579"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="647"/>
            <end position="675"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="687"/>
            <end position="705"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="729"/>
            <end position="741"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OBZ87800.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="741" mass="82728" checksum="B5466D0FC9137226" modified="2016-11-30" version="1">MNSGFNHADYPVIVGIDFGTTYSGCCYAFAQNEEVIDIVKWPKQNNQVYPKTPTLSLYRKGSTQLVEWGHGARRLAMKPNNADSLLLSKFKLYLDEHLQQTELGNGLNIIDVIADYLRAFHLHVCTELLKGFAGNYDQSRFRYCLTVPAMWSDRAKATMREAAIRAGLIDSTDHPDRLMLISEPEAAALYCEKKSEQFNLRHGQRFMICDAGGGTVDLIVFEIHEPPGERRTLKEVTNGHGGSCGSGFLDLRMREYLKRKFARYHTISDSAMELIMDTFVNVIKPDFDGVEDHFLDLPASMGLGDLTDAEIGLDNGSLCLPAEELRDFVFEPVIRQVLDLIRGQLLQSPQLEAIFLVGGFGQSNYLFRRVEDEFANQVGMIGVPPRGELAVVRGAVYFGLNPQIVTERVSRRTYGVETRMLFQEDIDPPEYSVVGADQKRYCRQRFSVYVHKGQSIKVDECVSKNFVISYXNDTDSDLFAFDGDGQPPRLTSHPLVRKVGNFPIRMPHLEGVKHGEKVNMTIKMYFGLTEIKIECIIRDKSFMFTSSFDAGDAYPASMNSSTLQAALPPPPMQQPPPQQPQNYAYAQAGYEYQTPLIASEQAYGMNDLTNNMSHVSLNQHQPYPASGAQGYPPSSAMGYPPSTNINYTPQQSYYPPSQQPASASASSSQAQAPTQGYRPMNYATNDYYNYPPQQQQSAYAQNNNSFYSTASGNAAGYSPSAQHGYPPQGNAQQNYGGNSYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NGE9</accession>
    <name>A0A1C7NGE9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Vesicular inhibitory amino acid transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">slc32a1_1</name>
        <name evidence="10" type="ORF">A0J61_03781</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the amino acid/polyamine transporter 2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000170">
        <property type="protein sequence ID" value="OBZ88167.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NGE9"/>
    <dbReference type="STRING" id="101091.A0A1C7NGE9"/>
    <dbReference type="InParanoid" id="A0A1C7NGE9"/>
    <dbReference type="OrthoDB" id="40134at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005774">
        <property type="term" value="C:vacuolar membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015179">
        <property type="term" value="F:L-amino acid transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1740.10">
        <property type="entry name" value="Amino acid/polyamine transporter I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013057">
        <property type="entry name" value="AA_transpt_TM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22950">
        <property type="entry name" value="AMINO ACID TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22950:SF692">
        <property type="entry name" value="TRANSMEMBRANE AMINO ACID TRANSPORTER FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01490">
        <property type="entry name" value="Aa_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0029">Amino-acid transport</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="50"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="74"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="122"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="164"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="188"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="227"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="266"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="308"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="349"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="376"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="410"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="domain" description="Amino acid transporter transmembrane" evidence="9">
        <location>
            <begin position="46"/>
            <end position="433"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008066"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OBZ88167.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="442" mass="48352" checksum="EE7EFE3496ACFFFD" modified="2016-11-30" version="1">MVFQESEKISVSPRNSFSQTFKIEETAIDNAIEDEQSITNEFGHGNGSVLTAYFSVVCVVAGTGTLGLPKAFALGGWLGILIMFLAYFMSVYSGIIIIRCLYYKPGHRLHNYKSVGMAAFGYPGYIIASVLHLLNLFGCPALYMVLASSNLNYLLRYTSGALDLKTWNCIIGAVLLIPGLVAKTLKEFTIISIIAVLSTVIAVFVVVVQGPIDHNSLPAGTVMTDGVIWTGFPSALATIAFSYGGINTYPHAEHALKKPHQWKWAVMAGMSTCTALYLLTAIPGYWSYGRSTLSPVYDSLNNETARMVAVIVMTVHVILAIPIYIISFSLEFEDWIKLSDDKHGKVGAWIIRCIVRTAAMAILVVLAIFVPYFDDFMSLIGALANCGLVFLLPVTCYLKLTGVRNKPWYELAFCAFTLFLGIVGCIFGSIDAIKALVRDFRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NGN8</accession>
    <name>A0A1C7NGN8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_04033</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000188">
        <property type="protein sequence ID" value="OBZ87919.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NGN8"/>
    <dbReference type="InParanoid" id="A0A1C7NGN8"/>
    <dbReference type="OrthoDB" id="2299989at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ87919.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="112" mass="12712" checksum="61977E1E1CD29ABC" modified="2016-11-30" version="1">MNAAIAVLTVEPTLSFSFAADPTSCDPSNFDATGQLKVQNLQVFFPEEFSLSQTCKHQLHGRVYSTYPTGVHFNSVDRTRVIEEKETFYKLYNLWGFVLSMDTVDSNNKLKH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NH58</accession>
    <name>A0A1C7NH58_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">AD domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_03858</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000175">
        <property type="protein sequence ID" value="OBZ88089.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NH58"/>
    <dbReference type="InParanoid" id="A0A1C7NH58"/>
    <dbReference type="OrthoDB" id="77463at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032797">
        <property type="term" value="C:SMN complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000245">
        <property type="term" value="P:spliceosomal complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000387">
        <property type="term" value="P:spliceosomal snRNP assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047574">
        <property type="entry name" value="AD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009422">
        <property type="entry name" value="Gemin6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046857">
        <property type="entry name" value="Gemin6_Sm-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14710">
        <property type="entry name" value="GEM-ASSOCIATED PROTEIN 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14710:SF2">
        <property type="entry name" value="GEM-ASSOCIATED PROTEIN 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06372">
        <property type="entry name" value="Gemin6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52001">
        <property type="entry name" value="AD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AD" evidence="1">
        <location>
            <begin position="55"/>
            <end position="147"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS52001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ88089.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="147" mass="17025" checksum="701A1A3DE42E1295" modified="2016-11-30" version="1">MYGFESNELVHLIGSKVRIVSKDLTTLEGYLYTVDPISHHVVLFQPDQDKVMVVFHHDIQQLTIHQQERSDTLHLPSLHLSTQTMAQRRQQLIALLKQHRVPIEYEDDDPVIYVLGCARVESPYVATSVVCDNPLIRQRVRNMILEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NHN1</accession>
    <name>A0A1C7NHN1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">tRNA N(3)-methylcytidine methyltransferase</fullName>
            <ecNumber evidence="4">2.1.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">METTL6</name>
        <name evidence="5" type="ORF">A0J61_03681</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">S-adenosyl-L-methionine-dependent methyltransferase.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the methyltransferase superfamily. METL family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.-" evidence="4"/>
    <dbReference type="EMBL" id="LUGH01000163">
        <property type="protein sequence ID" value="OBZ88269.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NHN1"/>
    <dbReference type="FunCoup" id="A0A1C7NHN1">
        <property type="interactions" value="201"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NHN1"/>
    <dbReference type="InParanoid" id="A0A1C7NHN1"/>
    <dbReference type="OrthoDB" id="417697at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052735">
        <property type="term" value="F:tRNA (cytidine-3-)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106217">
        <property type="term" value="P:tRNA C3-cytosine methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026113">
        <property type="entry name" value="METTL2/6/8-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22809">
        <property type="entry name" value="METHYLTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22809:SF5">
        <property type="entry name" value="TRNA N(3)-METHYLCYTIDINE METHYLTRANSFERASE METTL6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13489">
        <property type="entry name" value="Methyltransf_23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037755">
        <property type="entry name" value="Mettl2_prd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4 5" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4 5" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009725"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRNR" id="PIRNR037755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OBZ88269.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="280" mass="32678" checksum="F46AA4F7A4E14F85" modified="2016-11-30" version="1">MGDHSKVRADGARIVIEDERLEKLIERAQQVIAEDKKEVPAFWKTKYKKEAAKNWDLFYKRNTTKFFKELDRHWTDREFTELADQTKEQRCLEVGCGVGNFVFPLLADNPSLFIYACDFSKRAVDMVKENENYDESRCKAFVCDLTANKLTDNIPENSLDLVSAIFVFSAIPPEKMSIAIKNIYSVLKPGGYVLFRDYGLYDEAQIKFSAASDKKIDENLYVRHDGTLSYFFSTDDLKARFEQEGFIVDQLEYIYRETTNRSMEMRIDRIFAQAKFQKPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NHP1</accession>
    <name>A0A1C7NHP1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Peptidoglycan-N-acetylglucosamine deacetylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">pgdA_2</name>
        <name evidence="8" type="ORF">A0J61_03423</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Co(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:48828"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000147">
        <property type="protein sequence ID" value="OBZ88518.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NHP1"/>
    <dbReference type="STRING" id="101091.A0A1C7NHP1"/>
    <dbReference type="InParanoid" id="A0A1C7NHP1"/>
    <dbReference type="OrthoDB" id="2125469at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016810">
        <property type="term" value="F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd10951">
        <property type="entry name" value="CE4_ClCDA_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.370">
        <property type="entry name" value="Glycoside hydrolase/deacetylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011330">
        <property type="entry name" value="Glyco_hydro/deAcase_b/a-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002509">
        <property type="entry name" value="NODB_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46471">
        <property type="entry name" value="CHITIN DEACETYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46471:SF9">
        <property type="entry name" value="CHITIN DEACETYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01522">
        <property type="entry name" value="Polysacc_deac_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88713">
        <property type="entry name" value="Glycoside hydrolase/deacetylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51677">
        <property type="entry name" value="NODB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008889703" evidence="6">
        <location>
            <begin position="19"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="domain" description="NodB homology" evidence="7">
        <location>
            <begin position="40"/>
            <end position="242"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OBZ88518.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="258" mass="28546" checksum="49DD137678535A6C" modified="2016-11-30" version="1">MKSTLLITLATAAAVASAAPTSIEKRAVKAQIITTCTVPGTLALTFDDGPYEYTWALADTLRKAGVTATFFMNGNNWVNVETQSVKTPAGTKTYKQVIKHVYDKGHQIGSHTYSHLELGGQSTSKVNSEMDKLDKIFRSIIGKSPLYMRPPAGSYDSTTLAALGKKGYKVIMWDIDSNDWRYSTQASISKEQSNYKSVIEKDSKKNPHGHIALQHDVHKKTVEKLVPWVISYIKSKKNYKFVSVAECVGKTKNSAYRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NHS0</accession>
    <name>A0A1C7NHS0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_03411</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000146">
        <property type="protein sequence ID" value="OBZ88530.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NHS0"/>
    <dbReference type="InParanoid" id="A0A1C7NHS0"/>
    <dbReference type="OrthoDB" id="2264689at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="47"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="51"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ88530.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="289" mass="32730" checksum="D9378E953F2F6151" modified="2016-11-30" version="1">MGLPLWKPRDLVEDASPILHKSHRTDIADRDDNPWPNFSRQLMQHVHRRNSSPLHRNSQPRAQTRIGSRNSILTSSLVDRRRSSRAHLPGSSTSTSPPIRSELDRRLHQRITEKEDLLEQLSMTATLLDHFLAARSAYGSDAAILSSVLIEEFELPAILENAYSLIALTPSVLSITNSSNTTSSSRNGNREPNTLQEMVDRLLQIPPYSNRIQSIEQNIISAHRRIQDQLDLLGSAIPSRPHNSSSQLALTHTRSRVTSHTIESLPLSSDDWSHSRIRDEWNHNRMHGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NHY4</accession>
    <name>A0A1C7NHY4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Putative hexaprenyl pyrophosphate synthase, mitochondrial</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">COQ1_0</name>
        <name evidence="8" type="ORF">A0J61_03285</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the FPP/GGPP synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000139">
        <property type="protein sequence ID" value="OBZ88645.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NHY4"/>
    <dbReference type="FunCoup" id="A0A1C7NHY4">
        <property type="interactions" value="68"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NHY4"/>
    <dbReference type="InParanoid" id="A0A1C7NHY4"/>
    <dbReference type="OrthoDB" id="9927103at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990234">
        <property type="term" value="C:transferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004659">
        <property type="term" value="F:prenyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008299">
        <property type="term" value="P:isoprenoid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006744">
        <property type="term" value="P:ubiquinone biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.600.10">
        <property type="entry name" value="Farnesyl Diphosphate Synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008949">
        <property type="entry name" value="Isoprenoid_synthase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000092">
        <property type="entry name" value="Polyprenyl_synt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12001:SF69">
        <property type="entry name" value="ALL TRANS-POLYPRENYL-DIPHOSPHATE SYNTHASE PDSS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12001">
        <property type="entry name" value="GERANYLGERANYL PYROPHOSPHATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00348">
        <property type="entry name" value="polyprenyl_synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48576">
        <property type="entry name" value="Terpenoid synthases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0414">Isoprene biosynthesis</keyword>
    <keyword evidence="5" id="KW-0460">Magnesium</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0808">Transferase</keyword>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006706"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU004466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OBZ88645.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="269" mass="30038" checksum="1456C1B521033CA7" modified="2016-11-30" version="1" fragment="single">TPSYEEETIQSSPENPILPTQRRLAEISEMIYTASLLHYDIVDHAEQVTRPGFGNKLAVLGGDFLLARASLALAYLKNPECIELIATCIANLVEGEFMQLQHPHEKNPDQKKAFDYYLRKVYMKTGSLIAQSCKASSVLGGCLNETAAISYDYGKHLGMALQLIDDLRQFSQNAAHMDQKKMSQQITAPFLFAWEEVPELGPLIEREFSQEGDMEKARVLIYKSSALKRTLDLANLHIDSAIAAIEKLPPSDSRSALIQLAKNLPSRKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NIJ0</accession>
    <name>A0A1C7NIJ0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Sphingolipid C4-hydroxylase sur2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">sur2_1</name>
        <name evidence="7" type="ORF">A0J61_03005</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000122">
        <property type="protein sequence ID" value="OBZ88943.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NIJ0"/>
    <dbReference type="FunCoup" id="A0A1C7NIJ0">
        <property type="interactions" value="102"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NIJ0"/>
    <dbReference type="InParanoid" id="A0A1C7NIJ0"/>
    <dbReference type="OrthoDB" id="408954at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008610">
        <property type="term" value="P:lipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006694">
        <property type="entry name" value="Fatty_acid_hydroxylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050307">
        <property type="entry name" value="Sterol_Desaturase_Related"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11863">
        <property type="entry name" value="STEROL DESATURASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04116">
        <property type="entry name" value="FA_hydroxylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="27"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="73"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="132"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="domain" description="Fatty acid hydroxylase" evidence="6">
        <location>
            <begin position="143"/>
            <end position="279"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF04116"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OBZ88943.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="297" mass="34998" checksum="9582065FC1277486" modified="2016-11-30" version="1">MYALLRDHIDTNLEALKNPWSDEVLAVWLPIVAYWVYSIFWQVVMMAEWPFFEQYRIHTMGDMEKRNKVSLSRVLAMVVVQHIIQGVLGFLVLKPVDPMEYALAQEKQLNVWTGFFLSIFNRFELSFQLAQITQWVIVPLFQFFLAMAILDAHQYFLHRLFHVNKFLYKHVHSHHHRLYVPYAFGALYNHPLEGFLFDTCGAAIAAELARLSPRLTLIFFTFSTLKTVDDHCGYALPWDPLQFLFGNNVQYHDIHHQSFGIKTNFSQPFFTFWDRLLGTEMTLKEAEKKNKQRNAAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NIZ0</accession>
    <name>A0A1C7NIZ0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Vacuolar amino acid transporter 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">avt3_0</name>
        <name evidence="9" type="ORF">A0J61_02984</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the amino acid/polyamine transporter 2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000121">
        <property type="protein sequence ID" value="OBZ88960.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NIZ0"/>
    <dbReference type="FunCoup" id="A0A1C7NIZ0">
        <property type="interactions" value="82"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NIZ0"/>
    <dbReference type="InParanoid" id="A0A1C7NIZ0"/>
    <dbReference type="OrthoDB" id="1684102at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005774">
        <property type="term" value="C:vacuolar membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015179">
        <property type="term" value="F:L-amino acid transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013057">
        <property type="entry name" value="AA_transpt_TM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22950">
        <property type="entry name" value="AMINO ACID TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22950:SF666">
        <property type="entry name" value="VACUOLAR AMINO ACID TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01490">
        <property type="entry name" value="Aa_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="320"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="365"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="405"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="429"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="472"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="505"/>
            <end position="528"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="548"/>
            <end position="572"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="593"/>
            <end position="610"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="616"/>
            <end position="638"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="650"/>
            <end position="673"/>
        </location>
    </feature>
    <feature type="domain" description="Amino acid transporter transmembrane" evidence="8">
        <location>
            <begin position="288"/>
            <end position="670"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="34"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="232"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="49"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="232"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="265"/>
            <end position="274"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008066"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OBZ88960.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="687" mass="75562" checksum="79790263E59C3D17" modified="2016-11-30" version="1">MSSPLPVNAKQNYREGGSFLDDSILSSSFDRANSTARLGTSPAPGLYGTSPSRSVVSHRSYGSTDIENVLTNNSGGLFRPLSQATYNPEDNTVSVDLPDDQVARVVKRHLVDTSPSASLRSRSIFADDNDDQGSGSNIKSVHQLPGGAITHDIYKWAGDMENEQIKRQRSQSFYVPRNEPLDPALARLKDPGGFRRHFVVNKAERQGRQPSWMTRTFVDFLALYGHFGGEDLSEDEEGELNDEETGAAGGVVDSNRIRRRKRQDENEDDDDDENSPLIKARRNAVQGTATPAKAVFLLLKSFVGTGVMFLPKAFYNGGLLFSTSLLTFIALVSLYTFLLLVETRNKIPVSFGDIGGILFGSKMRFSVLLAITFSQIGFVCAYMVFVAQNVQALIESVSQCEVRVPLSYLILGQIAIFVPLAMIRKIQKLSAFALIADLFILVGLIYLYYYDFFILSTTGIADVEWVLNYKSFPMFIGTAVFTYEGVGLVIPITESMAEPEKFPKVLSGTMIFITAIFLSVGFISYMAFGSQVQTVILLNMPGTTMVNTVQGLYALAICLSIPLQLFPAIRIVENGLFTRSGKHNTMVKWQKNLFRFVSVLICATIAIAGSSDLDKFVSLVGSLCCVPLCFFFPPLFHLKAIAKTWRQKTIDIAIIVFGIASMTYTTGITISLWSEGGESAPISRCPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NJ06</accession>
    <name>A0A1C7NJ06_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Uncharacterized protein C57A7.05</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">A0J61_02961</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000120">
        <property type="protein sequence ID" value="OBZ88980.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NJ06"/>
    <dbReference type="STRING" id="101091.A0A1C7NJ06"/>
    <dbReference type="InParanoid" id="A0A1C7NJ06"/>
    <dbReference type="OrthoDB" id="2274698at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018823">
        <property type="entry name" value="ArAE_2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018820">
        <property type="entry name" value="BRE4-related_DUF2421"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023244">
        <property type="entry name" value="Brefeldin_A-sensitivity_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049453">
        <property type="entry name" value="Memb_transporter_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37994">
        <property type="entry name" value="ARAE_2_N DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10337">
        <property type="entry name" value="ArAE_2_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10334">
        <property type="entry name" value="BRE4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13515">
        <property type="entry name" value="FUSC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR02047">
        <property type="entry name" value="BREFELDNASP4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="66"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="91"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="120"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="156"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="182"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="214"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="605"/>
            <end position="624"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="655"/>
            <end position="678"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="684"/>
            <end position="702"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="709"/>
            <end position="727"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="747"/>
            <end position="767"/>
        </location>
    </feature>
    <feature type="domain" description="Putative ER transporter 6TM N-terminal" evidence="8">
        <location>
            <begin position="156"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="domain" description="Integral membrane bound transporter" evidence="9">
        <location>
            <begin position="629"/>
            <end position="758"/>
        </location>
    </feature>
    <feature type="domain" description="DUF2421" evidence="7">
        <location>
            <begin position="764"/>
            <end position="916"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="17"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF10334"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF10337"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF13515"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OBZ88980.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="984" mass="111267" checksum="E7A1B00EA7A06154" modified="2016-11-30" version="1">MEDIELSNQSSRRSHGHNSDTQEKHDDDMTATTTHHSQLSMMPEESIKQKSKAPGNILTKLLPLPLVRIVVKAAISILIALLFVFEDNCRNAMGSASVLVPIGTLLYFPVRPIGVQIEAAFQGTFGALLGSAWCFLGMYLASIVRDPAVISPVQPKSSAILAIFMFIGVFGLTYVRTKFAQANFATIFASIIVAFCLTQASIVRIFSTTLIYTFLKPIATATAIGLLVDIFLWPEDSITKYMGVMSRSLKEYNGFFEEHVTAFLSADMTSPNTITLPTLHQRLQNIVLKLIDSKREIQREILFNRLAHEDINDITRHIKLMRVPLHGIGLSLIAKLERLSNVGHDKIHENEHKKQFIEDLREARKSTQQLADVCVTTLNECTERLMKFSGKPRSTKSTLLWPFPRIFLSDYYKSTKEQQEDKAEQDKIKTIADRLHQAIAHFEAETRKPNRVFIDPGSSQYEVEFNSVLQVVYLFQYNLREHALHLQSFVQSIETIESKRTSRRLRFPKLPLRKWFRSISVDANLGAQLDSPANDPHASTGQTTNDLTLCQTTTRNDFVDTADGLVRQKKATYPRDPDVNPPETASEKFFYALYRFVEWLKSPDCAFSLKTAAGFVLISLPAFLPESATWFFAWRGQWATITLMMWMIPVTGMFVFSVILRVIGTVLGGVMGIVVWEIVRGNPYGLVVLTFFVMMPLYYIFFTSQIFKMVAIMTQLTLLLVVCYEYQYVVSGAATYDSVEVVAGKRMLLVIIGVAGAAILALIPKPVTGRVELRKRISRTIKDLGQLYSILVGDILAESEPTENQSKAFRKLALGIRRQIADEQTYLKLAKLEPPLRGKFPLETYATLVQKVDNMADLLQGMAYASKDIDKSWRRNIMEVTRQERKELIASNLSIMKLLSATLASKMALPPYMTPPNEMRTRFVQQMGDVISKYPNRLDNDTFPNYCAYSVNAYMFLGELSETLECVEKLVGIEDPDQWLLLHA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NJH9</accession>
    <name>A0A1C7NJH9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Hexose transporter 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">KHT2_0</name>
        <name evidence="11" type="ORF">A0J61_02962</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000120">
        <property type="protein sequence ID" value="OBZ88979.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NJH9"/>
    <dbReference type="FunCoup" id="A0A1C7NJH9">
        <property type="interactions" value="330"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NJH9"/>
    <dbReference type="InParanoid" id="A0A1C7NJH9"/>
    <dbReference type="OrthoDB" id="4142200at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005351">
        <property type="term" value="F:carbohydrate:proton symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd17356">
        <property type="entry name" value="MFS_HXT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000026">
        <property type="entry name" value="MFS quinate transporter QutD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050360">
        <property type="entry name" value="MFS_Sugar_Transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00879">
        <property type="entry name" value="SP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022:SF2">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00171">
        <property type="entry name" value="SUGRTRNSPORT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00216">
        <property type="entry name" value="SUGAR_TRANSPORT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00217">
        <property type="entry name" value="SUGAR_TRANSPORT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="63"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="112"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="139"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="164"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="197"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="228"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="336"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="371"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="402"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="437"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="474"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="502"/>
            <end position="523"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="10">
        <location>
            <begin position="72"/>
            <end position="527"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="39"/>
            <end position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="OBZ88979.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="568" mass="63611" checksum="C579DC7440A43B4E" modified="2016-11-30" version="1">MSYQHPVRESNHHTQDPPYIDSTQFDDNVPDNQEKQVKTYPSTSSGSDVYTTRRKTSNGFTGFVKNPYVCFTAVFASIGGVLFGYDQGVISGVQEMDDFVNRFPMNSTQTGFMVSILELGAWVGAWIIGYFADRISRKYSIILATIIFLLGSSIQGGAQNIGYLLGGRFVTGMGVGSLSLLVPLYQSEISPPEIRGSLVSLQQLAVTFGILISFWIDYGLTRVQGQASWRVPLCIQIAFALVLGVGILFFPFSPRWLMSKGREEEALQVISKLRRLPQDHPDVLEEWKEIKATVEFDRIVERQQYPQYVDQGSKGRLMIELAGYRELFRKGIFNRVAIGSMIMFFQQFSGMNALIYYAPKIFQSVGLTGNSVSLLATGVVGIINFVMTFPTVFFLDVVGRKIALMVASVLMAICMIVVAIITALFQHDWPNHTAEGWVSVAFIYIFIACFACTWGPIGWVIPAEIFPLRARAKAMSVTTSSNWMNNFIIGLIVPVMLENITYGTYIFFACFLILSFFFVWFFVPETKGRTLEEMDEIFGGQSAVHDADIMNQVQNNINQQPINKHTSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NJT8</accession>
    <name>A0A1C7NJT8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Guanine nucleotide-binding protein subunit gamma</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">gng-1_0</name>
        <name evidence="12" type="ORF">A0J61_02526</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="3">G proteins are composed of 3 units, alpha, beta and gamma.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the G protein gamma family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000096">
        <property type="protein sequence ID" value="OBZ89432.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NJT8"/>
    <dbReference type="STRING" id="101091.A0A1C7NJT8"/>
    <dbReference type="InParanoid" id="A0A1C7NJT8"/>
    <dbReference type="OrthoDB" id="19232at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005834">
        <property type="term" value="C:heterotrimeric G-protein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031681">
        <property type="term" value="F:G-protein beta-subunit binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007186">
        <property type="term" value="P:G protein-coupled receptor signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000750">
        <property type="term" value="P:pheromone-dependent signal transduction involved in conjugation with cellular fusion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="4.10.260.10:FF:000003">
        <property type="entry name" value="G-protein complex gamma subunit Ste18/GpgA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.260.10">
        <property type="entry name" value="Transducin (heterotrimeric G protein), gamma chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015898">
        <property type="entry name" value="G-protein_gamma-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036284">
        <property type="entry name" value="GGL_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041848">
        <property type="entry name" value="Ste18_fungal"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28189">
        <property type="entry name" value="GUANINE NUCLEOTIDE-BINDING PROTEIN SUBUNIT GAMMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28189:SF1">
        <property type="entry name" value="GUANINE NUCLEOTIDE-BINDING PROTEIN SUBUNIT GAMMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00631">
        <property type="entry name" value="G-gamma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01224">
        <property type="entry name" value="G_gamma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48670">
        <property type="entry name" value="Transducin (heterotrimeric G protein), gamma chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50058">
        <property type="entry name" value="G_PROTEIN_GAMMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0488">Methylation</keyword>
    <keyword evidence="7" id="KW-0564">Palmitate</keyword>
    <keyword evidence="10" id="KW-0636">Prenylation</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0807">Transducer</keyword>
    <feature type="domain" description="G protein gamma" evidence="11">
        <location>
            <begin position="2"/>
            <end position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007431"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011581"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00016111"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023289"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50058"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="OBZ89432.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="75" mass="8338" checksum="CDDA8F6D60553A0C" modified="2016-11-30" version="1">MPKQAIAEAKLRKLLELNEKLKEQLEISRIPVSEASRSMIEFCQSTEDLMVPSVWGNRSPDPFAEPTAGCGCTVM</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NJY7</accession>
    <name>A0A1C7NJY7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Chitin synthase regulatory factor 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">chr3_3</name>
        <name evidence="3" type="ORF">A0J61_02844</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000113">
        <property type="protein sequence ID" value="OBZ89109.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NJY7"/>
    <dbReference type="STRING" id="101091.A0A1C7NJY7"/>
    <dbReference type="InParanoid" id="A0A1C7NJY7"/>
    <dbReference type="OrthoDB" id="272077at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051726">
        <property type="entry name" value="Chitin_Synth_Reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006597">
        <property type="entry name" value="Sel1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46430:SF2">
        <property type="entry name" value="CHITIN SYNTHASE REGULATORY FACTOR 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46430">
        <property type="entry name" value="PROTEIN SKT5-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08238">
        <property type="entry name" value="Sel1"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SMART" id="SM00671">
        <property type="entry name" value="SEL1"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81901">
        <property type="entry name" value="HCP-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="161"/>
            <end position="194"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ89109.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="796" mass="89414" checksum="650707C54C94B98F" modified="2016-11-30" version="1">MYITQPYTTYVQQEPQIQRPLDTLYEDNDQRKKPLPKVPNINRHSTLVVGPSWTTGSIRTGADNGFGSVKAYLMNENTQQLEHQQNLYSNKQKTNKVTMLSPIEGYQGPMSEYPPYPPNTYYAIQPAVTQPENYVHHPVPPQSNSVSQEWKVSKNMTFKHPTVRRTDSLKIESSPIAPNEPQRLEKPDEPGILQRKVSKEEVCEQSEEKTVHLEKSNSFRLQPTSSEGLFTSASSVISESLSPSSSTSLIQKMTSSGVTLPNSGSGINLEKSNSMLNNSSIISTTDVCSQLSSLSRSATYYARNTKPSNLRVITDYEALGSADTPVTQIPNEPLENKRVNPISALHDPKNGVDHQDRFLESLKHSSLSIASYSLVQTKSNTKLYRRLAMKTRNHDIQMTFAKYLLQISKLYDSKTNLYQLKSQSEDDMVICDNNSNETPAQIRNRLLKEAGFWIERLSKSHWPEALYIKGRWHLLGRLQAPECVLPGYDKPNESKAFKCFMIASKGGWAEAHYELANLWKKRGHFAKAVRSYEKGAKENHTPSIYKMAKILLRGQLKEKKDVAKGLTYLKQAADAMSTDCAEPAFVLGCIYANEFDCIGITSNQDKQALRNAKLEDGDDYRYALKYMKKSAQFGYPDAIYYMGQISESGKLGQLCDVWQAYQYYSRAADLKHPGAMLDLSRLYCQGIPGLLAAQNDIAFKWCKRSADLGFDQAEFVLGIYYENGTGTEPDFPRALECFGRAASKGFQPAAEKLNQPLTSKAQQHHHIQSAKGQVTDASEVNNLIGNKRSTNNCVVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NK54</accession>
    <name>A0A1C7NK54_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Dynein light chain</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">Dynll1</name>
        <name evidence="10" type="ORF">A0J61_02584</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Acts as one of several non-catalytic accessory components of the cytoplasmic dynein complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in changing or maintaining the spatial distribution of cytoskeletal structures. Also a component of the nuclear pore complex.</text>
    </comment>
    <comment type="function">
        <text evidence="9">Acts as one of several non-catalytic accessory components of the cytoplasmic dynein complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in changing or maintaining the spatial distribution of cytoskeletal structures.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Cytoplasmic dynein consists of two catalytic heavy chains (HCs) and a number of non-catalytic subunits which present intermediate chains (ICs), light intermediate chains (LICs) and light chains (LCs).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Cytoplasm</location>
            <location evidence="1 9">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the dynein light chain family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000099">
        <property type="protein sequence ID" value="OBZ89370.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NK54"/>
    <dbReference type="FunCoup" id="A0A1C7NK54">
        <property type="interactions" value="172"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NK54"/>
    <dbReference type="InParanoid" id="A0A1C7NK54"/>
    <dbReference type="OrthoDB" id="10033309at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005868">
        <property type="term" value="C:cytoplasmic dynein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035974">
        <property type="term" value="C:meiotic spindle pole body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034399">
        <property type="term" value="C:nuclear periphery"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045505">
        <property type="term" value="F:dynein intermediate chain binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007017">
        <property type="term" value="P:microtubule-based process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd21452">
        <property type="entry name" value="DLC-like_DYNLL1_DYNLL2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.740.10:FF:000001">
        <property type="entry name" value="Dynein light chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.740.10">
        <property type="entry name" value="Protein Inhibitor Of Neuronal Nitric Oxide Synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037177">
        <property type="entry name" value="DLC_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019763">
        <property type="entry name" value="Dynein_light_1/2_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001372">
        <property type="entry name" value="Dynein_light_chain_typ-1/2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11886">
        <property type="entry name" value="DYNEIN LIGHT CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11886:SF35">
        <property type="entry name" value="DYNEIN LIGHT CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01221">
        <property type="entry name" value="Dynein_light"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01375">
        <property type="entry name" value="Dynein_light"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54648">
        <property type="entry name" value="DLC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01239">
        <property type="entry name" value="DYNEIN_LIGHT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7 9" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="5 9" id="KW-0243">Dynein</keyword>
    <keyword evidence="4 9" id="KW-0493">Microtubule</keyword>
    <keyword evidence="6 9" id="KW-0505">Motor protein</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00055833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU365010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OBZ89370.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="89" mass="10287" checksum="8F9EB97C7FA980DB" modified="2016-11-30" version="1">MSDAKAVVKSVDMSEEMQQEAIECSTQALEKYNIEKDIAAHIKREFDRKYGPTWHCVVGRNFGSFVTHESKHFIYFYHGQIAILLFKSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NK97</accession>
    <name>A0A1C7NK97_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Alpha-latrocrustotoxin-Lt1a</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">LCTA</name>
        <name evidence="5" type="ORF">A0J61_03016</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000123">
        <property type="protein sequence ID" value="OBZ88926.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NK97"/>
    <dbReference type="STRING" id="101091.A0A1C7NK97"/>
    <dbReference type="InParanoid" id="A0A1C7NK97"/>
    <dbReference type="OrthoDB" id="341259at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24198">
        <property type="entry name" value="ANKYRIN REPEAT AND PROTEIN KINASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24198:SF165">
        <property type="entry name" value="ANKYRIN REPEAT-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13637">
        <property type="entry name" value="Ank_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="143"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="176"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="15"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="40"/>
            <end position="49"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OBZ88926.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="380" mass="43016" checksum="6167B0733262933D" modified="2016-11-30" version="1">MMIPPLCLEKYHVTTSQQRQNLPTPPTSPDEVVTPIKRKQTADHSPSKRTRLDLTLLHRYLSSGKPVHVKDARYGLNLLCWACQCQSVEAVDSILNQGSIDINQRHGSRQMTALHMAALTNFHQGLQRLVNHPNLDINQRDTQGLTAVHYAARQNCAEALEVLIESGARIDIYDRQGRLPLHYAIMHGSQVVLKLLLTNQERNNPTGLNLIWSSLIHTSSLEEAIVITGNPDIIQMLIESGAFLSIEQGGWWEACYGAQYCQMLEHCIYWNRLSCLICLLKYKDRLPSLSSLSSLLHLAVQQRKLDIVQYLVKEHQVDPCHQDGSNPSLLYAVNHGFMEMIPFLLTSSTSSYCIQRACLLAHMIGQTQTWSQLVKAHWQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NKC8</accession>
    <name>A0A1C7NKC8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">ATP-dependent DNA helicase PIF1</fullName>
            <ecNumber evidence="14">5.6.2.3</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="14">DNA 5'-3' helicase PIF1</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="14">DNA repair and recombination helicase PIF1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="17" type="primary">pfh1_1</name>
        <name evidence="14" type="synonym">PIF1</name>
        <name evidence="17" type="ORF">A0J61_02441</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="14">DNA-dependent ATPase and 5'-3' DNA helicase required for the maintenance of both mitochondrial and nuclear genome stability.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="19">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="5.6.2.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 14">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="14">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
            <location evidence="2">Nucleolus</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="14">Nucleus</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="14">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="14">Belongs to the helicase family. PIF1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.6.2.3" evidence="14"/>
    <dbReference type="EMBL" id="LUGH01000092">
        <property type="protein sequence ID" value="OBZ89515.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NKC8"/>
    <dbReference type="FunCoup" id="A0A1C7NKC8">
        <property type="interactions" value="243"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NKC8"/>
    <dbReference type="InParanoid" id="A0A1C7NKC8"/>
    <dbReference type="OrthoDB" id="5578775at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043139">
        <property type="term" value="F:5'-3' DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000723">
        <property type="term" value="P:telomere maintenance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd18037">
        <property type="entry name" value="DEXSc_Pif1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18809">
        <property type="entry name" value="SF1_C_RecD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:001226">
        <property type="entry name" value="ATP-dependent DNA helicase PIF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03176">
        <property type="entry name" value="PIF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010285">
        <property type="entry name" value="DNA_helicase_pif1-like_DEAD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049163">
        <property type="entry name" value="Pif1-like_2B_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051055">
        <property type="entry name" value="PIF1_helicase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048293">
        <property type="entry name" value="PIF1_RRM3_pfh1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47642">
        <property type="entry name" value="ATP-DEPENDENT DNA HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47642:SF5">
        <property type="entry name" value="ATP-DEPENDENT DNA HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05970">
        <property type="entry name" value="PIF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21530">
        <property type="entry name" value="Pif1_2B_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 14" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 14" id="KW-0227">DNA damage</keyword>
    <keyword evidence="10 14" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="11 14" id="KW-0234">DNA repair</keyword>
    <keyword evidence="8 14" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6 14 17" id="KW-0347">Helicase</keyword>
    <keyword evidence="5 14" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="12 14" id="KW-0413">Isomerase</keyword>
    <keyword evidence="9 14" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="3 14" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13 14" id="KW-0539">Nucleus</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="16">
        <location>
            <begin position="306"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="DNA-binding region" evidence="14">
        <location>
            <begin position="691"/>
            <end position="710"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="89"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="123"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="206"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="15">
        <location>
            <begin position="97"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="15">
        <location>
            <begin position="128"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="15">
        <location>
            <begin position="206"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="15">
        <location>
            <begin position="249"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="15">
        <location>
            <begin position="273"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <begin position="314"/>
            <end position="321"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="OBZ89515.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="732" mass="82677" checksum="CD09AC28CE5707C7" modified="2016-11-30" version="1">MKRNTAQQKKSGNTLFNYFTKVKEPVQKESLSSLIERTSISREVHTPPQTHIRQTTTKTTEINHVSKTKQTVDLTNDSDDDLILIPSSQQDTATFDSSPFSSQSSNRSDFLYTEEMTNTSKYNKKGWSIQQKESGPQKSSQDPNIEYERPSSQKFDRIVLQKPRITPKARYDWLSNNDVKPYSSSQHHYSAKNEVKRFELPVTRILPSSPQYGTGKQNKRNRDDSSFESWMPPSKQKKTVHGIKKERATSSSSSWSTSSSASRSNQRRVLPTTPMSQLASRSQITTEYRPELSEEQQRVFDMVVHAHQSLFFTGSAGTGKSVLLRAIIDRLRSQYGSQLAVTASTGIAACNINGCTLHSFGGIGIGQDSADQLYHKVLNSKRAKERWIETTVLIIDEISMVDADLFDKLNIIAKRIRRNDKPFGGMQIVVTGDFFQLPPVNPNKVSKFAFEANAWQEAITQTVMLTQVFRQKDGTFVRILNEMRLGRLSNEAINIFSSLSRTPEGDNEIEPTELYPLRNEVDSSNKRRLDELKGETVEFKAVDVGDPRKISGCIAPAVMHLKLHAQVMLLKNIDSDLVNGSLGVVIGFVGKGEYRSKKKCEFLRTPQKLANYTMENELDMNVPYPIVKFSGERILLLERETWSFSLPGGNVEASRHQIPLMLAWAISIHKSQGQTLDRVRVDLGKVFEKGQAYVALSRATNLETLQILNFDPSKVMAHPTVTRFYQTLQTVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NKY6</accession>
    <name>A0A1C7NKY6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">NAD-dependent histone deacetylase HST3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">HST3_0</name>
        <name evidence="6" type="ORF">A0J61_02813</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the sirtuin family. Class I subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000111">
        <property type="protein sequence ID" value="OBZ89146.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NKY6"/>
    <dbReference type="FunCoup" id="A0A1C7NKY6">
        <property type="interactions" value="62"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NKY6"/>
    <dbReference type="InParanoid" id="A0A1C7NKY6"/>
    <dbReference type="OrthoDB" id="2919105at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017136">
        <property type="term" value="F:histone deacetylase activity, NAD-dependent"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070403">
        <property type="term" value="F:NAD+ binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1600.10">
        <property type="entry name" value="SIR2/SIRT2 'Small Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1220">
        <property type="entry name" value="TPP-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029035">
        <property type="entry name" value="DHS-like_NAD/FAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050134">
        <property type="entry name" value="NAD-dep_sirtuin_deacylases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003000">
        <property type="entry name" value="Sirtuin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026591">
        <property type="entry name" value="Sirtuin_cat_small_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026590">
        <property type="entry name" value="Ssirtuin_cat_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11085:SF8">
        <property type="entry name" value="NAD-DEPENDENT HISTONE DEACETYLASE HST3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11085">
        <property type="entry name" value="NAD-DEPENDENT PROTEIN DEACYLASE SIRTUIN-5, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02146">
        <property type="entry name" value="SIR2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52467">
        <property type="entry name" value="DHS-like NAD/FAD-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50305">
        <property type="entry name" value="SIRTUIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0520">NAD</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Deacetylase sirtuin-type" evidence="5">
        <location>
            <begin position="11"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="4">
        <location>
            <position position="142"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="150"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="153"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="175"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="178"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006924"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50305"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OBZ89146.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="334" mass="37749" checksum="1ED0E3D7146360F1" modified="2016-11-30" version="1">MRTRINISEPTKVDDLLITELANCIKNSRKALVITGAGISCSSGIPDFRSANGLYDLVKRKYPGTVLKGQDLFDAHLFKDQRQTQCFYTLMAELKSVMSAATPTLTHTFIRALQERGQLMRCYTQNIDCLEDSVELSVVRLHGAMDRVKCTLCTASYEFTSDYEALFRTGLPPVCPQCELFGSERIKLGKRSLSMGTLRPNIVLYNEAHPDGETIGRLQCTDLRRKPDLMIVMGTSLKIPGLKRFIKQAAKQIHSSSKNGKVVFVNKTAPSKEWDKVFDYEVLGDTDDWVKLTQTKLGLKLKNESDATKIVIKRKQKPLRVSMRLLKKYKKKLC</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NL08</accession>
    <name>A0A1C7NL08_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Ricin B lectin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">A0J61_02796</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000110">
        <property type="protein sequence ID" value="OBZ89166.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NL08"/>
    <dbReference type="STRING" id="101091.A0A1C7NL08"/>
    <dbReference type="InParanoid" id="A0A1C7NL08"/>
    <dbReference type="OrthoDB" id="2124915at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd23454">
        <property type="entry name" value="beta-trefoil_Ricin_GllA-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.80.10.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035992">
        <property type="entry name" value="Ricin_B-like_lectins"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000772">
        <property type="entry name" value="Ricin_B_lectin"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00652">
        <property type="entry name" value="Ricin_B_lectin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00458">
        <property type="entry name" value="RICIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50370">
        <property type="entry name" value="Ricin B-like lectins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50231">
        <property type="entry name" value="RICIN_B_LECTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008889760" description="Ricin B lectin domain-containing protein" evidence="2">
        <location>
            <begin position="30"/>
            <end position="895"/>
        </location>
    </feature>
    <feature type="domain" description="Ricin B lectin" evidence="3">
        <location>
            <begin position="512"/>
            <end position="645"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="37"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="695"/>
            <end position="895"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="37"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="702"/>
            <end position="715"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="739"/>
            <end position="753"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="785"/>
            <end position="797"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="821"/>
            <end position="834"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00458"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OBZ89166.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="895" mass="96398" checksum="2A1A227B711E197B" modified="2016-11-30" version="1">MLSNIMKHSIRLSIIFAVILTYCNLTVLAKGGGGGGRGGGGGGGFSSPGSGAGSGGSYSRGGGYTGRSGYGGTNSGRGVAGTGNTPSSVSSKGGSGGFGGAPPPTYASTRNTYTNYAPAYGGGYTPTSRYGYTGYYNPVLPYFFIMPPFLFLGYHSAYHRYNQQTGYYYAPRLTEQGSSTQNVIINGTANSGKEDNYHYTFNISTNNQFPMADHAFFSTSDFSAPVADFVYRLQFSHLVEFDDANQNGFYDANEEILSVSSLRNLPWTSFQVSNITVPNNATQAYLQTGTSANVPYNGTGSNFSVRITYRSSNLQLNQTAPIVIQPNSLQYDFAVEGFPANIASTRPNARLAVAQVVSTAQDVPIVFDVNATTPVDVANQIKTNQTYGLSIGDYTEGRLEYQNSVNISDVTSAPGELNAQNLAGIPSYSENDWIWGSNSSAANRNNKLLLITLPGYNNNGTGVNTAFSGFGFLDTDVMSSMSSSGSPSSSRGMMLSTDLSLLKTIGLIPLFKGPFYILSRKHGFALDVYDGQTKEDANIIVWPQKFQDSDNQLWTFDNGRLINKKSGHALDISSSAFKRDKSIVQKKIKPSKQSQEWIYDQGFICSKEFPTLVLDIRGDSPKGGAQVLLYKRKDTDNLNQLWQFEPYQQFEGALNLATTSVPLHKKEGFGQPRPGYGAEVGVPPELKQIPENNKIAGVGNNIAPTKTSNTTNEPANSRHDPLLAQYGSFYGGTQTSPSPAEPGPVPPLPPKYPPSSNSAPSPSAFPQPIPASSVPSTTYPPPASHYSTSPNQNSTGYPNYPPHDAHVNRYPDYPPAGFAHPPQQQQQLSMSPPLNGQGYPAPPLPNRNSQGDQYGYPPPPLPDRNSQNQYGYPPPPPSLPNRPQDQYGYPPSAYP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NLE1</accession>
    <name>A0A1C7NLE1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">40S ribosomal protein S24</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">RPS24_0</name>
        <name evidence="7" type="ORF">A0J61_02051</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the eukaryotic ribosomal protein eS24 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000073">
        <property type="protein sequence ID" value="OBZ89885.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NLE1"/>
    <dbReference type="FunCoup" id="A0A1C7NLE1">
        <property type="interactions" value="586"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NLE1"/>
    <dbReference type="InParanoid" id="A0A1C7NLE1"/>
    <dbReference type="OrthoDB" id="5571754at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.3370:FF:000001">
        <property type="entry name" value="40S ribosomal protein S24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.3370">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00545">
        <property type="entry name" value="Ribosomal_eS24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053709">
        <property type="entry name" value="eRP_eS24_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001976">
        <property type="entry name" value="Ribosomal_eS24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018098">
        <property type="entry name" value="Ribosomal_eS24_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012678">
        <property type="entry name" value="Ribosomal_uL23/eL15/eS24_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10496">
        <property type="entry name" value="40S RIBOSOMAL PROTEIN S24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01282">
        <property type="entry name" value="Ribosomal_S24e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54189">
        <property type="entry name" value="Ribosomal proteins S24e, L23 and L15e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00529">
        <property type="entry name" value="RIBOSOMAL_S24E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 7" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="97"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="103"/>
            <end position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009680"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU004381"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU004383"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OBZ89885.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="130" mass="14963" checksum="6BCB466BED0DA56C" modified="2016-11-30" version="1">MADATVTIRTRKFLTNRLLQRKQMVVDVIHPGLPNVSKDELRTKIGKMYKAEKDVVSVFGFKTHFGGGKTTGFALIYDNVEALKKFEPKHRLVRIGLAEAPKGGRKQRKEKKNREKKFRGVRKSKKPRKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NLG0</accession>
    <name>A0A1C7NLG0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Rho guanine nucleotide exchange factor gef2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">gef2</name>
        <name evidence="3" type="ORF">A0J61_02010</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000071">
        <property type="protein sequence ID" value="OBZ89937.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NLG0"/>
    <dbReference type="InParanoid" id="A0A1C7NLG0"/>
    <dbReference type="OrthoDB" id="660555at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005085">
        <property type="term" value="F:guanyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.900.10">
        <property type="entry name" value="Dbl homology (DH) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057454">
        <property type="entry name" value="Bud3_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035899">
        <property type="entry name" value="DBL_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000219">
        <property type="entry name" value="DH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051092">
        <property type="entry name" value="FYVE_RhoGEF_PH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12673">
        <property type="entry name" value="FACIOGENITAL DYSPLASIA PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12673:SF270">
        <property type="entry name" value="FYVE-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25351">
        <property type="entry name" value="PH_BUD3_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00621">
        <property type="entry name" value="RhoGEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00325">
        <property type="entry name" value="RhoGEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48065">
        <property type="entry name" value="DBL homology domain (DH-domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50010">
        <property type="entry name" value="DH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DH" evidence="2">
        <location>
            <begin position="116"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="660"/>
            <end position="680"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="708"/>
            <end position="744"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="780"/>
            <end position="879"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="671"/>
            <end position="680"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="708"/>
            <end position="720"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="789"/>
            <end position="803"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="831"/>
            <end position="857"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ89937.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="1040" mass="119423" checksum="4F14EE9D01FB6C42" modified="2016-11-30" version="1">MEGNTKDILLDTPFRHPCNIYKESSIPILRDHNVSDQCKEIGRHLLNMTKNPLSQHVDVLIPKLDRSNHAKSQLEHFKSFFGQKHIVQESEKNSTEDAEVQNRIAMSKNAFLFESPITKPIKEFIDTERSYVELLEEIVHKVMKRIKESIVHENKSPILDHYSFNRIFINMEDILEVNKAFLDSLKQYEQGIASESFGEIVLRHINTFDCYRVYLLGKSNSLACHTQNIKQNKNYSKFLLSMDVKGSLGMSDILISPIQRMARYKLLIGVVANALDXKDVEIEYLRQAEDKVSKINDMQYGDSSLLNLYHLIREAPASLIQTRQLLGYFDATELSLLSGKSNRPVTILVFTDKLMVVKRKSYSLQGKDMLDNIEEKVKNTMSTSMLQKAKEAYTGLPFEFKGWVDIKAVEFFHGLKDRSDTFFLRTTLPELDPNATEKEAEEYFRRSDRLYSIIPSTNTKSVNLNQFIENKNKLIALCQKQFALSKIQDTSVELYCEDKFKLPAYTHFFDEDSYSSAKQKNHILIVYVEDNKSIRHININKLVDDNVWIIVLLSRHQTSGGYKLVIRAKTGLVPIREISRDMEYECIVDTQSAQRKNNHEPLDFIDTLWNNLFFYERRLXATDAFSCINDGLLRVRSRSRSRSKSLTRVASNMSIGKLFARSRSSSPTRHSAVEAQHDSLLDQAPTSHVLDPVLKIATVNKQVEAEFRAQNKESLSEKHGYRPPKINTQPRHRHSTDFRSSSPSEIFVRNDTHFIDDFNEKKNIPEEMLYSGSNCYQDNSYRHPRPYPSTSATTSTSSRSLGSIHGYFNNTDPSLPLRYSPQGHHRRSPSPEHSISRPSSGGSRHSVTSLSSENTPSDPYPSHNISRRPTEPFGTYGGSVGSYHSGSSRSYFDDYSKPFDFLPPSSPHREKYYGSTRSIGSSTYDEKLMSAIDNPRGVMYGSRPPLHPGFYTQPQSPNVLPRQPALAHRPHTAPAVDNCAQLKNDVNELIDELIQSHNHRRAHDYNNYESMRDMRSHINSKFDELINNINQTQQYQHQHH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NLM1</accession>
    <name>A0A1C7NLM1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Cytochrome c oxidase subunit NDUFA4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">ndufa4</name>
        <name evidence="2" type="ORF">A0J61_01933</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000067">
        <property type="protein sequence ID" value="OBZ90033.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NLM1"/>
    <dbReference type="STRING" id="101091.A0A1C7NLM1"/>
    <dbReference type="InParanoid" id="A0A1C7NLM1"/>
    <dbReference type="OrthoDB" id="5511684at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010530">
        <property type="entry name" value="B12D"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14256:SF1">
        <property type="entry name" value="GEO09626P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14256">
        <property type="entry name" value="NADH-UBIQUINONE OXIDOREDUCTASE MLRQ SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06522">
        <property type="entry name" value="B12D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="22"/>
            <end position="41"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ90033.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="87" mass="10020" checksum="941B56A3D0A01917" modified="2016-11-30" version="1">MAGPAANAAKKTFWSIWYKHEIIPIFVTVGGACALAGYHLAKLARGPEVVWDRTNNPYPWQNIDQDTQVKYMTVNQKFDKKYARDRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NMK6</accession>
    <name>A0A1C7NMK6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Major facilitator superfamily domain-containing protein 6</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">Mfsd6_1</name>
        <name evidence="8" type="ORF">A0J61_01592</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. MFSD6 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000052">
        <property type="protein sequence ID" value="OBZ90371.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NMK6"/>
    <dbReference type="InParanoid" id="A0A1C7NMK6"/>
    <dbReference type="OrthoDB" id="515887at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024989">
        <property type="entry name" value="MFS_assoc_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051717">
        <property type="entry name" value="MFS_MFSD6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16172">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN 6-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16172:SF41">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN 6-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12832">
        <property type="entry name" value="MFS_1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="21"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="57"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="88"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="129"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="159"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="182"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="263"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="297"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="346"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="414"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily associated" evidence="7">
        <location>
            <begin position="24"/>
            <end position="418"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF12832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OBZ90371.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="454" mass="50654" checksum="41A2D20EEDE11B2D" modified="2016-11-30" version="1">MLIVIDEQQDVRPYTDKANNFIGLKLLSVFSIGCIGSAQMFLPVFYKKVLELGNDKIGFMFSITPLVSLIAMPYWTSLVDRTGEYKKVMIRNMLVALGCIWSIAFVPYVSEQDWIRILLTSMGCFGYAFFGYPVIAALVDAVTLRVLAERKDLYGRQKIGVPIGFASSVFLTGFLIEKFGSPYALFVVFGAFALLFIVTIACIDVQPPEYEPLDENTDYGATTPPQPVVAQVKDDDDGECEINDENQTASIWYLLQTPESVQFFTFVILLGSTFSVIQAFLYLFFEHDVEGGTASMLGLFGPLGSSTEIVCFFFSKQARPNAMLIASQCFIIYRCFIYMIATDLTFGAWLVTVTQLLHGMGFSLAWSAGALQADRIAPPHLKSSAQGLLNMAYNGVSGFNVLLTGYIYETYGSRAMWSFTFFLGILSIVLYQSAYLRKTVFTWIANLIRQKFIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NMN3</accession>
    <name>A0A1C7NMN3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Solute carrier family 28 member 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">Slc28a3</name>
        <name evidence="12" type="ORF">A0J61_01758</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000059">
        <property type="protein sequence ID" value="OBZ90210.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NMN3"/>
    <dbReference type="STRING" id="101091.A0A1C7NMN3"/>
    <dbReference type="InParanoid" id="A0A1C7NMN3"/>
    <dbReference type="OrthoDB" id="6075923at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005337">
        <property type="term" value="F:nucleoside transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015293">
        <property type="term" value="F:symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008276">
        <property type="entry name" value="C_nuclsd_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011657">
        <property type="entry name" value="CNT_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002668">
        <property type="entry name" value="CNT_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011642">
        <property type="entry name" value="Gate_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10590">
        <property type="entry name" value="SODIUM/NUCLEOSIDE COTRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10590:SF4">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 28 MEMBER 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07670">
        <property type="entry name" value="Gate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07662">
        <property type="entry name" value="Nucleos_tra2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01773">
        <property type="entry name" value="Nucleos_tra2_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="63"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="142"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="200"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="289"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="419"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="455"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="516"/>
            <end position="539"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="551"/>
            <end position="573"/>
        </location>
    </feature>
    <feature type="domain" description="Concentrative nucleoside transporter N-terminal" evidence="9">
        <location>
            <begin position="176"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="domain" description="Nucleoside transporter/FeoB GTPase Gate" evidence="11">
        <location>
            <begin position="258"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="domain" description="Concentrative nucleoside transporter C-terminal" evidence="10">
        <location>
            <begin position="363"/>
            <end position="571"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01773"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF07662"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF07670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="OBZ90210.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="574" mass="63377" checksum="AC6A27DD75C038B2" modified="2016-11-30" version="1">MQQKEKDNDHLAVSVKDGEQSEATHEQDGDRRAQSVSSVSFISSTTSNRWIDRLKKTAFKYRLYIHIVLWLLMSGFVCAAYVLQVPKGYNQELLVLGLLYGFISLRLLSRHLSFDPIIYPWYSITQKSLFYLNHHLSDRIRTIGYAACVMGIIIATVLAFPEKQESPRLKRLVSLLGMLVFISCTYASSKNRKAIRWNTIFTALLFQFLLALFVFHTSVGQDLFNWILQFAVGYMHKASYGAEFLFGTAAVNANTFALNLFPVIIFFNSTVQMLFYVGALQWIFRKLSIVFMAFLDISGVEAIVAAATIKPFLGACENALLIEPFAPKLTRSEIHQIMTCGFATVSGSTLYIYTSMGVSGQALITSCIMSIPSSIAVSKLRYPETELSETREARGIVIEIKDDVSNIVHAATKGATAGIHIALTIGACVITVLATLYAVNAFLTWLGQFLNIPELTLQLITGYLFVPIAWFIGADNQDVVKVGSLMAIKIWSNEFIAFREMIDVYKGQLTPKSELVATYALCGFANLGTVGMQIGVLSAIAPKRSDAISEIAISALICGSISTWLSAAMAGMLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NNS2</accession>
    <name>A0A1C7NNS2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_01171</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000034">
        <property type="protein sequence ID" value="OBZ90761.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NNS2"/>
    <dbReference type="InParanoid" id="A0A1C7NNS2"/>
    <dbReference type="OrthoDB" id="2291008at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="8"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="18"/>
            <end position="35"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ90761.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="153" mass="17899" checksum="1E683F38CC69405B" modified="2016-11-30" version="1">MNYHHRSIPSLSSSISSNDTHSPRTSSSSINYSCPNLKQSAPLKLNTQIHQKRLSEPLSPISPMTPKVKRWDDSQLEMELAEDDLIESSQKKVRRNSSLRLKEKLQLSESFIKEKLRSHKREYSDDDILYYTTQNKNKTKLSRSLKKVYDWLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NNX3</accession>
    <name>A0A1C7NNX3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_01160</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000034">
        <property type="protein sequence ID" value="OBZ90787.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NNX3"/>
    <dbReference type="InParanoid" id="A0A1C7NNX3"/>
    <dbReference type="OrthoDB" id="10043543at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="57"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="88"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="176"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="210"/>
            <end position="234"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ90787.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="254" mass="29704" checksum="AECD39BD9576540D" modified="2016-11-30" version="1">MKHQMDQFNKNICTQDDRYLLVQEETISINSSISSTLKDTQEQKPTLKERILAFWKIARPFVVIALVISGVPALLRVIYVFWKRRQVELLGCIFVVTFIISGVLSSISTAIIGFTFLITLIPIKTRWFRFRPFFFSIYQQMMVDKPAVEWTDTNGERKSVLNEEWLWTYYRSYRRYCYTASAIWGVAMTGEFIAKIIMIQSSLTIDQIIMIGNIAFNLLIVVLLILTAVSMYYMTQRGSVELKQWLIKNDHTFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NPJ2</accession>
    <name>A0A1C7NPJ2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Spermidine synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">spe-3</name>
        <name evidence="6" type="ORF">A0J61_00910</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the spermidine/spermine synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000024">
        <property type="protein sequence ID" value="OBZ91045.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NPJ2"/>
    <dbReference type="FunCoup" id="A0A1C7NPJ2">
        <property type="interactions" value="590"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NPJ2"/>
    <dbReference type="InParanoid" id="A0A1C7NPJ2"/>
    <dbReference type="OrthoDB" id="38125at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004766">
        <property type="term" value="F:spermidine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015940">
        <property type="term" value="P:pantothenate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008295">
        <property type="term" value="P:spermidine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.140.10:FF:000001">
        <property type="entry name" value="SPE3p Spermidine synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.150:FF:000013">
        <property type="entry name" value="Spermidine synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.140.10">
        <property type="entry name" value="Spermidine synthase, tetramerisation domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00198">
        <property type="entry name" value="Spermidine_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030374">
        <property type="entry name" value="PABS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030373">
        <property type="entry name" value="PABS_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001045">
        <property type="entry name" value="Spermi_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030668">
        <property type="entry name" value="Spermi_synthase_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035246">
        <property type="entry name" value="Spermidine_synt_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037163">
        <property type="entry name" value="Spermidine_synt_N_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF002010">
        <property type="entry name" value="PRK00811.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00417">
        <property type="entry name" value="speE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11558:SF11">
        <property type="entry name" value="SPERMIDINE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11558">
        <property type="entry name" value="SPERMIDINE/SPERMINE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17284">
        <property type="entry name" value="Spermine_synt_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01564">
        <property type="entry name" value="Spermine_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000502">
        <property type="entry name" value="Spermidine_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01330">
        <property type="entry name" value="PABS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51006">
        <property type="entry name" value="PABS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0620">Polyamine biosynthesis</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3 4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PABS" evidence="5">
        <location>
            <begin position="12"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="3">
        <location>
            <position position="167"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007867"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00354"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003836"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OBZ91045.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="293" mass="33239" checksum="74E82E8126C7B145" modified="2016-11-30" version="1">MAAPLTHPLINDGWFMEKNSQWPGQAMSLKVEEILHVEKSQYQDVLVFQSANYGNVLVLDGVIQATERDEFSYQEMITHLAMNSHPCPKKVLVIGGGDGGVLREVVKHECVEEATLVDIDEAVPRVSKKYLPNMSIGFEHPKVTLHIGDGFEFLKDKFNQYDVIITDSSDPDGPAESLFGPDFFQLLKNALTEKGVFSTQGECMWLHLPLIRKVKDFCKNLYPQVEYAYTCIPTYPSGQIGHIMCSKDPEANIREPLRKFTPEQEEKLLRYYNSEIHKAAFVLPQFAKKALNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NPL1</accession>
    <name>A0A1C7NPL1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Putative isochorismatase family protein YddQ</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">yddQ</name>
        <name evidence="4" type="ORF">A0J61_02794</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the isochorismatase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000110">
        <property type="protein sequence ID" value="OBZ89164.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NPL1"/>
    <dbReference type="InParanoid" id="A0A1C7NPL1"/>
    <dbReference type="OrthoDB" id="245563at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01014">
        <property type="entry name" value="nicotinamidase_related"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.850">
        <property type="entry name" value="Isochorismatase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000868">
        <property type="entry name" value="Isochorismatase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050272">
        <property type="entry name" value="Isochorismatase-like_hydrls"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036380">
        <property type="entry name" value="Isochorismatase-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43540:SF1">
        <property type="entry name" value="ISOCHORISMATASE HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43540">
        <property type="entry name" value="PEROXYUREIDOACRYLATE/UREIDOACRYLATE AMIDOHYDROLASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00857">
        <property type="entry name" value="Isochorismatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52499">
        <property type="entry name" value="Isochorismatase-like hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Isochorismatase-like" evidence="3">
        <location>
            <begin position="4"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="unsure residue" description="D or N" evidence="4">
        <location>
            <position position="185"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OBZ89164.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="185" mass="20975" checksum="07507F4FB1BF7C49" modified="2016-11-30" version="1">MKEALILIDIQNDYFPNGXXPXWRPVETAESCKVVLEHFRKHQKEVVHVKHHCVGPDAEKFKXLLPGTHGAEIHELVKPLPEEKVVVKEHMNGFWETDLGAYLKSKKIERLVFVGMMIHNCVPATLFAGKDDGFECVVVDEAVNTMSQPLHGEMIQAEDIKKAYLAGIQFAYAKVKKVEEILNED</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NPP3</accession>
    <name>A0A1C7NPP3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Putative 2-oxoglutarate dehydrogenase E1 component DHKTD1, mitochondrial</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">dhtkd1</name>
        <name evidence="6" type="ORF">A0J61_01541</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>thiamine diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58937"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the alpha-ketoglutarate dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000050">
        <property type="protein sequence ID" value="OBZ90406.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NPP3"/>
    <dbReference type="STRING" id="101091.A0A1C7NPP3"/>
    <dbReference type="InParanoid" id="A0A1C7NPP3"/>
    <dbReference type="OrthoDB" id="413077at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016624">
        <property type="term" value="F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030976">
        <property type="term" value="F:thiamine pyrophosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006091">
        <property type="term" value="P:generation of precursor metabolites and energy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd02016">
        <property type="entry name" value="TPP_E1_OGDC_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12470">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.970">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11610">
        <property type="entry name" value="Multifunctional 2-oxoglutarate metabolism enzyme, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.1150">
        <property type="entry name" value="TPP helical domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011603">
        <property type="entry name" value="2oxoglutarate_DH_E1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001017">
        <property type="entry name" value="DH_E1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042179">
        <property type="entry name" value="KGD_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031717">
        <property type="entry name" value="ODO-1/KGD_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029061">
        <property type="entry name" value="THDP-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005475">
        <property type="entry name" value="Transketolase-like_Pyr-bd"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00239">
        <property type="entry name" value="2oxo_dh_E1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006914">
        <property type="entry name" value="PRK09404.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF008907">
        <property type="entry name" value="PRK12270.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23152:SF4">
        <property type="entry name" value="2-OXOADIPATE DEHYDROGENASE COMPLEX COMPONENT E1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23152">
        <property type="entry name" value="2-OXOGLUTARATE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00676">
        <property type="entry name" value="E1_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16870">
        <property type="entry name" value="OxoGdeHyase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02779">
        <property type="entry name" value="Transket_pyr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000157">
        <property type="entry name" value="Oxoglu_dh_E1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00861">
        <property type="entry name" value="Transket_pyr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52518">
        <property type="entry name" value="Thiamin diphosphate-binding fold (THDP-binding)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0786">Thiamine pyrophosphate</keyword>
    <feature type="domain" description="Transketolase-like pyrimidine-binding" evidence="5">
        <location>
            <begin position="585"/>
            <end position="790"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00861"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OBZ90406.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="938" mass="106673" checksum="F8CFB932C618BE90" modified="2016-11-30" version="1">MFRQATRNRLTQYTNTRFSLRKRSYHDDGVYGYRVPKEFKMPDYTSEELSNRMKYGSLLRMIQAYRTHGHEGAHLDPLNIMKRKEVLALKPERYGLDKSQSDLYNLAGILHVNDAVQEQSVTSKNEADFETILNHLQAVYCGKIAYEFMHLPSASERRWWYHAVESWDKPQMTTEQKKRIHHLLSKSEVFDHFLAKKFPNVKRYGLEGAESMMVALDRLFELSAQQGIQDVVIGMPHRGRLNLLCDLLEYPHAALFHKMKGHPEVPADTFASGDVISHLTNNPTLDYNGKPVHVSLLPNPSHLEAINPVAMGKARAKQTGLLSSQSDTDCNLGDRVMCVQIHGDAAFSSQGIVMESLAMSNLPHYSSGGSIHIVVNNQLGYTTPAQNARSSAYCSDIGKMINAPVVHVNGDFPEDVARALDVVFEYRNKFRKDIILDLMCYRRWGHNELDEPAFTQPLMYNNIRHRTSVPKLYEKKLLEEKVLTSDQEATSIRERHVEALESQLAKAEGYVPDADQFHLDKNWKGMQHIKTGKEQQRPDTGVDSHTLVEIGELSVTPPEGIQVHPRLQKYHIDQRIKKLKASQAIDWATAEALAFGSLIQEGYDVRISGQDVGRGTFSQRHAMFVCQQTERAFVPLNHMKKDQKNFLEVANSPLSEYGVLGFEYGMSMESPRRLVLWEAQFGDFFNGAQITIDTFLSSGEEKWLKQSGLVMLLPHGQDGAGPEHSSSRVERFLQMSNDTFDVEKADNVPPNWHIVNCTTPAQYFHVLRRQMLRDYRKPLIVVSPKSLLKSPVAVSRLDDMAPGTSFQPVLTDSSIQDPSKVEKVVFVSGKFYYDLVKERDQRQLNDKMALIRVEEMSPFPKKELEREISQFSGAQQFIWCQEEHQNAGAYAFMAPRLAQLLPSPLKYVGREPLSSPAVGISSLFKKQSSHLLEQLMKH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NQ28</accession>
    <name>A0A1C7NQ28_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Bifunctional methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">prmC</name>
        <name evidence="2" type="synonym">trmB</name>
        <name evidence="2" type="ORF">A0J61_00725</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000018">
        <property type="protein sequence ID" value="OBZ91221.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NQ28"/>
    <dbReference type="STRING" id="101091.A0A1C7NQ28"/>
    <dbReference type="InParanoid" id="A0A1C7NQ28"/>
    <dbReference type="OrthoDB" id="269872at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009982">
        <property type="term" value="F:pseudouridine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001522">
        <property type="term" value="P:pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2350.10">
        <property type="entry name" value="Pseudouridine synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002052">
        <property type="entry name" value="DNA_methylase_N6_adenine_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025714">
        <property type="entry name" value="Methyltranfer_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050320">
        <property type="entry name" value="N5-glutamine_MTase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020103">
        <property type="entry name" value="PsdUridine_synth_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18895">
        <property type="entry name" value="HEMK METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18895:SF74">
        <property type="entry name" value="MTRF1L RELEASE FACTOR GLUTAMINE METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13847">
        <property type="entry name" value="Methyltransf_31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55120">
        <property type="entry name" value="Pseudouridine synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00092">
        <property type="entry name" value="N6_MTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransferase" evidence="1">
        <location>
            <begin position="372"/>
            <end position="472"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ91221.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="554" mass="62684" checksum="E28785C7A86F93F7" modified="2016-11-30" version="1">MSEHKANIAHLKIIVPNESDHQRIRKYLLQHYRELFSSKENLHRSFVRKEISLNGVVSEETQFIKAGDVIEIKYDKHLEEARKIEAIPISICYEDDHLAIVWKPSGLNPVMFEKAVRYNIAKRESVEEKLFCINDIQKAASGLVIVAKTENAKKLMLQLYNEDKIEMIMRVLCHGFVSDTDISVFFQADKSGLTAPEKVVRSMTIVSQTPSNNSGHITCLDLSLHTPLNSVNLRRAFYSHSSHPIIGNSQFTCPLKVNSDKGLCTSLISISFTHPILNTPIVSIQPEPSKFKVICDREERFFNKKKEKQIEQLKEAGIDPDSLAENQIASYVISQKEFCGHVFKITKDCLIPRRSSETLVRATVDAVGIDRENTRIIDMGTGCGNLLISILKRLSSSATGVGIDISEAALKMAAENSSKLLSGNNGDKIKWLVRDIHTFSLPPSEKPFDVLVCNPPYLDQTKVSKTKRELNTFEQEPPEALFAGRNGYEWYHILKDVAIMVLRQDGVVVLECGRGMMQKVKELWLDDGWQQHAVYKDDQGWDRCLVLKRSVSNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NQ35</accession>
    <name>A0A1C7NQ35_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_00729</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000018">
        <property type="protein sequence ID" value="OBZ91225.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NQ35"/>
    <dbReference type="InParanoid" id="A0A1C7NQ35"/>
    <dbReference type="OrthoDB" id="2286987at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ91225.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="391" mass="44553" checksum="DE4A849FC47C9FBE" modified="2016-11-30" version="1">MTTDNRKQIRNSTETEYKKILDLWQIQSKYLSFGPSDFEQQDLLGLFYCFLNQVWSDAQQMSQNTWRKQEETSCTTMGLYWMKQAVVARQKVIDLMSSNNNVLNDSAATIQHGLVYPSFAKTSISSSASDTFRPTKIRSSPSTPTLSNFGSKCDDQAICMQSSQVETDHFATMSRKGLSCYHCHEKVGMKRSFSANDAYTFDHASNSSYHSAESSRRDDDSEVCDDDGNDISQPFSPCVCDKHTSYPYMNRQSMTNYNMSCYCYCYQSETDESNDGNDYDDTSISGSKLLLKKEDTVLDECYKEKLVKYMLIEQVDEADKDNQDCISLQPSSNSSCNNLGLPVDDITNQQKKDREELRRYICCEYNNLEIKDSCNSPLVSESQLIKPAILI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NQE2</accession>
    <name>A0A1C7NQE2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Sorting nexin MVP1</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Sorting nexin mvp1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="primary">mvp1_3</name>
        <name evidence="12" type="ORF">A0J61_00644</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
            <orientation evidence="1">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the sorting nexin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000015">
        <property type="protein sequence ID" value="OBZ91323.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NQE2"/>
    <dbReference type="FunCoup" id="A0A1C7NQE2">
        <property type="interactions" value="102"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NQE2"/>
    <dbReference type="InParanoid" id="A0A1C7NQE2"/>
    <dbReference type="OrthoDB" id="10064318at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005768">
        <property type="term" value="C:endosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032266">
        <property type="term" value="F:phosphatidylinositol-3-phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006623">
        <property type="term" value="P:protein targeting to vacuole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042147">
        <property type="term" value="P:retrograde transport, endosome to Golgi"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06866">
        <property type="entry name" value="PX_SNX8_Mvp1p_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1520.10:FF:000042">
        <property type="entry name" value="Sorting nexin mvp1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1520.10">
        <property type="entry name" value="Phox-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001683">
        <property type="entry name" value="PX_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036871">
        <property type="entry name" value="PX_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028662">
        <property type="entry name" value="SNX8/Mvp1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035704">
        <property type="entry name" value="SNX8/Mvp1_PX"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045734">
        <property type="entry name" value="Snx8_BAR_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47554">
        <property type="entry name" value="SORTING NEXIN MVP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47554:SF1">
        <property type="entry name" value="SORTING NEXIN MVP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00787">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19566">
        <property type="entry name" value="Snx8_BAR_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00312">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64268">
        <property type="entry name" value="PX domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50195">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0653">Protein transport</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="domain" description="PX" evidence="11">
        <location>
            <begin position="257"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="189"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="230"/>
            <end position="246"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004287"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00014268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00072009"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="OBZ91323.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="632" mass="72738" checksum="BC2BD5C485CEE590" modified="2016-11-30" version="1">MLHEDEDPLGSSIFDDVNSSLLSNTMTTSIFSSQYDEDPWGSHSTPITHQTARSFTAPNLYVNTTSDNDHHAVMDVHRLSANTVLSGVQLPELYEQLFAQYQRSGRVSLSSLNTILLKGKISANQIETIMQVVVPNGASYVTQTEFDTALALLACAQNKLDITLDSLHDNRNFLPEPIIYQDSKEIKSPLKPVDENPIAPEPNTKSNHQHHSPTMTRAAYPGMKSPKGSLQDKHDQQSTTGEDRRLSSIDTRHWFESIEEVTVTVAPEREGFIFKHVNYIVTNEKRSSIVLRRYSDFWWLLEVLLRRYPFRALPNLPPKKLGGRDTAFLEKRRKGLSRFINAIIRHPVLRHDEIVARFLTEPSELSAWRKQNPPNLDEEFRRKHHPIRELDSMTPTNLEEQMQKARKRVTAGINHYVNLCFIMERMIRRMHGQATDFSRYSIALNSLAEAELRYHAGECRNCQYVVRGYETVAKHMQAESSLLEDQVGNATDGVLENLKQFRDLLVSFRDLDERRARLSNNQTDAISKRIQANRSKLHQNKGVPGLEAETQKLEESVRTDEKELAFQQDREVFIRYSLWSELIYLHKQQAFVSTLYQNFTKSAVHFSKLRAENWQDLEEPAFNMPSDIASFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NQN4</accession>
    <name>A0A1C7NQN4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Caltractin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">CATR</name>
        <name evidence="4" type="ORF">A0J61_00509</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000011">
        <property type="protein sequence ID" value="OBZ91431.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NQN4"/>
    <dbReference type="STRING" id="101091.A0A1C7NQN4"/>
    <dbReference type="InParanoid" id="A0A1C7NQN4"/>
    <dbReference type="OrthoDB" id="26525at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016460">
        <property type="term" value="C:myosin II complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050230">
        <property type="entry name" value="CALM/Myosin/TropC-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23048:SF0">
        <property type="entry name" value="CALMODULIN LIKE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23048">
        <property type="entry name" value="MYOSIN LIGHT CHAIN 1, 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13499">
        <property type="entry name" value="EF-hand_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13833">
        <property type="entry name" value="EF-hand_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00054">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0106">Calcium</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="EF-hand" evidence="3">
        <location>
            <begin position="5"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="3">
        <location>
            <begin position="123"/>
            <end position="157"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OBZ91431.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="157" mass="17971" checksum="025B7B16DFAECE7F" modified="2016-11-30" version="1">MKKSLTKKQATQVFKDHDINDEGILDGTYLVKALRFLGLPITEADIPDLLECVGREKDRFVNLDEFLEIMTELKNNEDDVEEDAFEGDELIADKAFEMLVDPSTNAITLESLLRACKEQDETWTRQQVVEMMHEADLNHDGMIDSKEFTMICRKAGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NQX8</accession>
    <name>A0A1C7NQX8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Glycosyltransferase-like protein LARGE2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">gyltl1b_1</name>
        <name evidence="8" type="ORF">A0J61_00409</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000009">
        <property type="protein sequence ID" value="OBZ91545.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NQX8"/>
    <dbReference type="STRING" id="101091.A0A1C7NQX8"/>
    <dbReference type="InParanoid" id="A0A1C7NQX8"/>
    <dbReference type="OrthoDB" id="411524at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015020">
        <property type="term" value="F:glucuronosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042285">
        <property type="term" value="F:xylosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035269">
        <property type="term" value="P:protein O-linked glycosylation via mannose"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00761">
        <property type="entry name" value="Glyco_tranf_GTA_type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="entry name" value="Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051292">
        <property type="entry name" value="Xyl/GlcA_transferase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12270:SF25">
        <property type="entry name" value="GLYCOSYLTRANSFERASE-LIKE PROTEIN LARGE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12270">
        <property type="entry name" value="GLYCOSYLTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13896">
        <property type="entry name" value="Glyco_transf_49"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0735">Signal-anchor</keyword>
    <keyword evidence="8" id="KW-0808">Transferase</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="6"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004606"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OBZ91545.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="419" mass="49379" checksum="E1448445E155F5CD" modified="2016-11-30" version="1">MALPKAVNYIIVVYIVCSILYTSSYLLGFRGSRSSFSNVSDSTVAKLQERYQSKQLVDWKNTFGQVVESTPEDLVLSKVFDETFGPSKVIPYYFKATEKIDHEEITMATLVTRNRFKVLSRLASHYKGPVSVAIHINDDDQKQETLDELKQLYEENEDMRRYVDLHLVVDKFDRQFNMWRNVAKFFARSDYIMMLDVDFYLCTDFRKSLQKQPQLMSLLREGKAAIVVPAFEYVDESDGEDWNKFPKTKQELLVDVGTEKLDMFHRGWTRGHGSTNYNKWYKQTSPYKVTEYNYSYEPYVIFKKEGTPWCDERFVGYGANKAACLFEIYLAGIDYWVLPDDFLIHQTHHYPEDTRAKERTYNKKLYDYYREETCLRYARIMIAADEWDTPKSTNLKKECGRIRGFNDVIGRIAEEHNEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NR06</accession>
    <name>A0A1C7NR06_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Prephenate dehydrogenase [NADP(+)]</fullName>
            <shortName evidence="2">PRDH</shortName>
            <ecNumber evidence="2">1.3.1.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">tyr1</name>
        <name evidence="4" type="ORF">A0J61_00439</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>prephenate + NADP(+) = 3-(4-hydroxyphenyl)pyruvate + CO2 + NADPH</text>
            <dbReference type="Rhea" id="RHEA:21640"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:29934"/>
            <dbReference type="ChEBI" id="CHEBI:36242"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.3.1.13"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Amino-acid biosynthesis; L-tyrosine biosynthesis; (4-hydroxyphenyl)pyruvate from prephenate (NADP(+) route): step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the prephenate/arogenate dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.3.1.13" evidence="2"/>
    <dbReference type="EMBL" id="LUGH01000010">
        <property type="protein sequence ID" value="OBZ91468.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NR06"/>
    <dbReference type="FunCoup" id="A0A1C7NR06">
        <property type="interactions" value="109"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NR06"/>
    <dbReference type="InParanoid" id="A0A1C7NR06"/>
    <dbReference type="OrthoDB" id="5399569at2759"/>
    <dbReference type="UniPathway" id="UPA00122">
        <property type="reaction ID" value="UER00962"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070403">
        <property type="term" value="F:NAD+ binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008977">
        <property type="term" value="F:prephenate dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004665">
        <property type="term" value="F:prephenate dehydrogenase (NADP+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006571">
        <property type="term" value="P:tyrosine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.3660.10:FF:000004">
        <property type="entry name" value="Prephenate dehydrogenase [NADP(+)]"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3660.10">
        <property type="entry name" value="6-phosphogluconate dehydrogenase C-terminal like domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008927">
        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050812">
        <property type="entry name" value="Preph/Arog_dehydrog"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003099">
        <property type="entry name" value="Prephen_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012385">
        <property type="entry name" value="Prephenate_DH_fun"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21363">
        <property type="entry name" value="PREPHENATE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21363:SF0">
        <property type="entry name" value="PREPHENATE DEHYDROGENASE [NADP(+)]"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036510">
        <property type="entry name" value="PDH_fung"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48179">
        <property type="entry name" value="6-phosphogluconate dehydrogenase C-terminal domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51176">
        <property type="entry name" value="PDH_ADH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="2" id="KW-0057">Aromatic amino acid biosynthesis</keyword>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="1 2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0827">Tyrosine biosynthesis</keyword>
    <feature type="domain" description="Prephenate/arogenate dehydrogenase" evidence="3">
        <location>
            <begin position="9"/>
            <end position="288"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRNR" id="PIRNR036510"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OBZ91468.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="439" mass="49807" checksum="E6652D0CAD0B5EE3" modified="2016-11-30" version="1">MTDLEKETIEIGIIGAGGMGRFYAQRISSAGWKKRDKRLQWQLRKNNENLGTNIKVWRDGFDISRRCDWIMYAVEAEYIDSVVKTFGPATKIGAIVGGQTSVKLPEVNALEKYLPDDTHIISCHSMHGPGVDPTGQPLIIIKHRATDEKLALAVRILSCFKSNIAHLTAEEHDRITADTQAVTHAAFLTMGSAWKSNAQFPWLLPHFVGGIENVKVNVALRIYSNKWHVYAGLAIMNPTAKVQITQYALSVADLFKLMIQEKEEEFRARVKTAGEYVFGGLQKDHTPILLDDTILDEFSLSKIPKENKTPNSHLSLLAMVDCWYRLKLNPYEHMVCQTPLFRIWMGITEYLFRHPTMLDDAIHAALYRKDIRPDDMEFVTCARGWAESVSLGSMEGYQKRFEETANYFRDEFAESTAVGNKMIAMISRNLMSTHQAQDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NR16</accession>
    <name>A0A1C7NR16_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">C-factor</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_00381</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000008">
        <property type="protein sequence ID" value="OBZ91561.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NR16"/>
    <dbReference type="FunCoup" id="A0A1C7NR16">
        <property type="interactions" value="126"/>
    </dbReference>
    <dbReference type="InParanoid" id="A0A1C7NR16"/>
    <dbReference type="OrthoDB" id="9876299at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016616">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05325">
        <property type="entry name" value="carb_red_sniffer_like_SDR_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052184">
        <property type="entry name" value="SDR_enzymes"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45458:SF1">
        <property type="entry name" value="SHORT CHAIN DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45458">
        <property type="entry name" value="SHORT-CHAIN DEHYDROGENASE/REDUCTASE SDR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU000363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ91561.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="240" mass="25998" checksum="FD504C2211917938" modified="2016-11-30" version="1">MSGKALTYLITGSSRGIGLEFVRQLAGSGHKVFASARQPEQSESLKSLINNENVFGVPLDVTDSKSIEEAVFQVSKDAPEGIDVLINNAGIGGQGSRTVFETPEEDFLNKFKTNTLGAANVTNAFLPLLRQAETRKIMNMSTVLASIQSRGPDSKIKSAVAFSVSKTALNMLTRLTASQLAAEDFIVYASHPGWVKTDFGGINATMSPERSVKAQLEVLKNLKLEDNGKFLDFRGKEIPW</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NR59</accession>
    <name>A0A1C7NR59_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Swiss Army Knife 2H phosphoesterase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_00325</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000007">
        <property type="protein sequence ID" value="OBZ91593.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NR59"/>
    <dbReference type="InParanoid" id="A0A1C7NR59"/>
    <dbReference type="OrthoDB" id="19045at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054498">
        <property type="entry name" value="2H-SAK"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22547">
        <property type="entry name" value="2H-SAK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Swiss Army Knife 2H phosphoesterase" evidence="2">
        <location>
            <begin position="13"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="67"/>
            <end position="86"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF22547"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ91593.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="240" mass="27114" checksum="82C20DE44F0B1ADE" modified="2016-11-30" version="1">MSNELDLLPVARYLSLKGSYIDQLGSQPESLVKEVHIRHRLDRDGANDGHHITVINHLEIASFIQHDQTDPTSSASQQKKASKRQHREALFGIHQQAIDLLGPAAGWEKPVDLGLGQCRDGASVSYFRVVHWPLGQELRRQLGLGFTNFHITVGFVPNDVHLYKGPASLICLQPGQPLSRKRAKLLISVASFYYHDTKFFKLLGRQCWKHGYYAEMASLTQVYVTCKEVQKNNSIYLPRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NUK2</accession>
    <name>A0A1C7NUK2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">A0J61_00788</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion inner membrane</location>
            <topology evidence="2">Single-pass membrane protein</topology>
            <orientation evidence="2">Matrix side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the complex I NDUFB3 subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000020">
        <property type="protein sequence ID" value="OBZ91174.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NUK2"/>
    <dbReference type="STRING" id="101091.A0A1C7NUK2"/>
    <dbReference type="InParanoid" id="A0A1C7NUK2"/>
    <dbReference type="OrthoDB" id="521512at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022900">
        <property type="term" value="P:electron transport chain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032981">
        <property type="term" value="P:mitochondrial respiratory chain complex I assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012576">
        <property type="entry name" value="NDUFB3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15082:SF2">
        <property type="entry name" value="NADH DEHYDROGENASE [UBIQUINONE] 1 BETA SUBCOMPLEX SUBUNIT 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15082">
        <property type="entry name" value="NADH-UBIQUINONE OXIDOREDUCTASE B12 SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08122">
        <property type="entry name" value="NDUF_B12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0249">Electron transport</keyword>
    <keyword evidence="11 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="7" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0679">Respiratory chain</keyword>
    <keyword evidence="6 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="38"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004298"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005667"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022660"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="OBZ91174.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="15">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="67" mass="7850" checksum="399EF46FEF61D9A8" modified="2016-11-30" version="1">MKSHVQAQVKTPVYHDPWAKREAWRKHPIFSKASNFKTMFPGLGIATVAFTAYCTYEHFFLNKKSHH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NWS7</accession>
    <name>A0A1C7NWS7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_00042</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000001">
        <property type="protein sequence ID" value="OBZ91904.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NWS7"/>
    <dbReference type="InParanoid" id="A0A1C7NWS7"/>
    <dbReference type="OrthoDB" id="2380640at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024368">
        <property type="entry name" value="Ecl1/2/3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12855">
        <property type="entry name" value="Ecl1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="87"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="102"/>
            <end position="111"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ91904.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="153" mass="17295" checksum="1BF4226191761A25" modified="2016-11-30" version="1">MCDTNWCTFCDCAIKPELDSIYCSEKCFQRDAFSYTTIHTKQYDVPALKTLPLLSTSREDYTQSYQIESSNSSICSDDLAAMHLDMLRSSPPNGSHTRRPPSLSFTRSRSNSSHNLETSFLATPDNTMVINQKLSSFPIVESLTKKSEQNKCK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-06-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7LMP5</accession>
    <name>A0A1C7LMP5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_11922</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01002700">
        <property type="protein sequence ID" value="OBZ66041.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="InParanoid" id="A0A1C7LMP5"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ66041.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="214" mass="24493" checksum="DCF45E41E26AC338" modified="2016-11-30" version="1" fragment="single">IPVSANLFTPAESDDIRFRNLAMEDGWSISTSNNIRDHINYRLDKAGVTTVDXTQKVSSLSSIIALIKRVISFSPVVEHETCKKGCYLFHVDNNSNMKHCPVCNEERDLCKPTKIKYMSIARKIAQLLSVDGKRNELLYRHETFEQDKLHLNDDFLPLDQGVLLAVNGFKSRKSSKAMMIIHVILLNYEPTIRFNEHNMFQAATVTRKTVQKKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MTL3</accession>
    <name>A0A1C7MTL3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_11759</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01002441">
        <property type="protein sequence ID" value="OBZ80192.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MTL3"/>
    <dbReference type="InParanoid" id="A0A1C7MTL3"/>
    <dbReference type="OrthoDB" id="2289822at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ80192.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="95" mass="10512" checksum="28E09AD6BD98FEED" modified="2016-11-30" version="1" fragment="single">TYKVVWYVCKIVCCFEFLLDKSPNGVPSHSVLGEVFESCNRQSVSLMPEVKKAASTRKNLVAFDARDLASPVSLLKEVKSVENGRVLVSPILKVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MUC0</accession>
    <name>A0A1C7MUC0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">E2 ubiquitin-conjugating enzyme</fullName>
            <ecNumber evidence="1">2.3.2.23</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">UBE2T_1</name>
        <name evidence="8" type="ORF">A0J61_11563</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.23" evidence="1"/>
    <dbReference type="EMBL" id="LUGH01002197">
        <property type="protein sequence ID" value="OBZ80388.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MUC0"/>
    <dbReference type="STRING" id="101091.A0A1C7MUC0"/>
    <dbReference type="InParanoid" id="A0A1C7MUC0"/>
    <dbReference type="OrthoDB" id="9978460at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061631">
        <property type="term" value="F:ubiquitin conjugating enzyme activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd23805">
        <property type="entry name" value="UBCc_UBE2T"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.110.10:FF:000060">
        <property type="entry name" value="Ubiquitin conjugating enzyme (UbcB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.110.10">
        <property type="entry name" value="Ubiquitin Conjugating Enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050113">
        <property type="entry name" value="Ub_conjugating_enzyme"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000608">
        <property type="entry name" value="UBC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016135">
        <property type="entry name" value="UBQ-conjugating_enzyme/RWD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24067">
        <property type="entry name" value="UBIQUITIN-CONJUGATING ENZYME E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00179">
        <property type="entry name" value="UQ_con"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00212">
        <property type="entry name" value="UBCc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54495">
        <property type="entry name" value="UBC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50127">
        <property type="entry name" value="UBC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="4" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="UBC core" evidence="7">
        <location>
            <begin position="5"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="153"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="369"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="154"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="195"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="264"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="289"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="337"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="393"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012486"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OBZ80388.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="393" mass="44407" checksum="999DD42AFB78F79F" modified="2016-11-30" version="1" fragment="single">MLSGILTNRLQRELLDLEKDPPPGVSCYPKDDNITELEAFIKGPPDSPYEKGLFRLDIRIPQNYPFDPPQIRFMTLIYHPNIDDTGRICADILKKGQGWNPALNLSTTLLLLSQLLAQPNPDDPLDAEIAKEYQLSYPTFKQKAIEYTEKYATEDTTASTHENSILPEQLPDPSDQKDKQEQEEEEEYEWSTSQKKTKLSLSRRKTAPEKSTISEKAVTLEKAVLEKTTAPKKPIALQKKAILEQPTQPPDCVDPPTRKPAKEPNSSFLSKPNQPTKKKPSSPLTTTTNHKSTFGQKEQSCTVTAERYAPTKEEEEEEASTSTSKVTPLKLIPTQQDDPHDSLEEMKKGSTKRTLSQLFDKEIIVLSDDEDDSHTSNVPVLHSLQLDRKQKRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MUF4</accession>
    <name>A0A1C7MUF4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Transcriptional regulator CBF1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">CBF1</name>
        <name evidence="6" type="ORF">A0J61_11436</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01002034">
        <property type="protein sequence ID" value="OBZ80515.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MUF4"/>
    <dbReference type="FunCoup" id="A0A1C7MUF4">
        <property type="interactions" value="209"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7MUF4"/>
    <dbReference type="InParanoid" id="A0A1C7MUF4"/>
    <dbReference type="OrthoDB" id="71302at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11398">
        <property type="entry name" value="bHLHzip_scCBP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.280.10">
        <property type="entry name" value="Helix-loop-helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011598">
        <property type="entry name" value="bHLH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047206">
        <property type="entry name" value="bHLHzip_scCBP1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036638">
        <property type="entry name" value="HLH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47787">
        <property type="entry name" value="CENTROMERE-BINDING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47787:SF1">
        <property type="entry name" value="CENTROMERE-BINDING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00010">
        <property type="entry name" value="HLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00353">
        <property type="entry name" value="HLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47459">
        <property type="entry name" value="HLH, helix-loop-helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50888">
        <property type="entry name" value="BHLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BHLH" evidence="5">
        <location>
            <begin position="57"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="155"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="127"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="38"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="62"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50888"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OBZ80515.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="175" mass="20059" checksum="5116BCB40BE1C4D3" modified="2016-11-30" version="1" fragment="single">TEANSSEALQAATQQQEQSKTKKGSSSHSGNGALKQPKVSETKDDKPPVGSAEWHKLRRENHKQVERRRRETINDGINEIARIVPGCEKNKGSILQRAAAYIRQLKETEASSMEKWTLEKLLTDQAMSELNRQVEVLKSELDRIRMENSYLKRELEAATSHRRDNSKRQKLDHEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MUV4</accession>
    <name>A0A1C7MUV4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Integrase catalytic domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_11338</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001922">
        <property type="protein sequence ID" value="OBZ80613.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7MUV4"/>
    <dbReference type="InParanoid" id="A0A1C7MUV4"/>
    <dbReference type="OrthoDB" id="5592268at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015074">
        <property type="term" value="P:DNA integration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.10:FF:000032">
        <property type="entry name" value="Retrovirus-related Pol polyprotein from transposon 297-like Protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.340.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001584">
        <property type="entry name" value="Integrase_cat-core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041588">
        <property type="entry name" value="Integrase_H2C2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050951">
        <property type="entry name" value="Retrovirus_Pol_polyprotein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37984:SF15">
        <property type="entry name" value="INTEGRASE CATALYTIC DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37984">
        <property type="entry name" value="PROTEIN CBG26694"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17921">
        <property type="entry name" value="Integrase_H2C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00665">
        <property type="entry name" value="rve"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50994">
        <property type="entry name" value="INTEGRASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Integrase catalytic" evidence="1">
        <location>
            <begin position="80"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50994"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ80613.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="350" mass="41108" checksum="43D80DEFF5003406" modified="2016-11-30" version="1" fragment="single">LIDKSSTETSEFCLPKVSNHYVPSSPTWGHFAYSNTLYKISHKYYWDNMSRSIMEYIKQCPKCQLQGRKQLQERLNPIPVTSKPFERVGIDVKHVSTSRLGSKYIVVAIDYLNKYVGARALQFQTSSDVALFLYERVICLHGTPVFIHTDNGRPMISELMRQVCKQFNINHKTITPYNSQSQGLVERFNRVIDQVLQRLKPEQKKDWDHYIEATLFAYRSIKHETTKRSPFFLLYGYEPNVPFDNTHRLFDSKATSFEYELTIRLSQQILXLKRIREQVTQYIATSQKNQIKRIDKVLLETKKELKPAFKIGDQVLLYKDYRSTSWSGKIETTWDGIFKIQNLEEYTETG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MV15</accession>
    <name>A0A1C7MV15_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_11685</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01002342">
        <property type="protein sequence ID" value="OBZ80266.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7MV15"/>
    <dbReference type="InParanoid" id="A0A1C7MV15"/>
    <dbReference type="OrthoDB" id="2275032at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="136"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ80266.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="136" mass="15423" checksum="549C9CB1280DC7A8" modified="2016-11-30" version="1" fragment="single">MNSTADANSYSGFRPRLIEFHGYEGEDFRHFKHALDTFFSICGINSASRKLTILVSQLGRAAAIFYSRYLKTIKAENSDAAPTYDEVINVLQEKYITPALVQRFELAFNDMVXGQNESPQLFLSRLYEAAELAEID</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MV19</accession>
    <name>A0A1C7MV19_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Helitron helicase-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_11291</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001874">
        <property type="protein sequence ID" value="OBZ80660.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MV19"/>
    <dbReference type="STRING" id="101091.A0A1C7MV19"/>
    <dbReference type="InParanoid" id="A0A1C7MV19"/>
    <dbReference type="OrthoDB" id="2285856at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025476">
        <property type="entry name" value="Helitron_helicase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10492">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10492:SF57">
        <property type="entry name" value="ATP-DEPENDENT DNA HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14214">
        <property type="entry name" value="Helitron_like_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helitron helicase-like" evidence="1">
        <location>
            <begin position="1"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="460"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF14214"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ80660.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="460" mass="53032" checksum="CA051D9C90152D78" modified="2016-11-30" version="1" fragment="single">MVKQYQYSMAIVGYFGKPSLFIIFTANPRWIEIQRELLPGQNAPDRPDLVARVFDLKVKNVGLPHLHLLLFLDSSHAIHSADEIDRTISAEIPSKESDPELYKIVTKNMVHGPCGNLNTKSPCMVKDANRNLKCSKRFPKTFTEQTVISDDGYPLYKRARSTDLNSRYSIRDPLGQGNGSIVIDDRWIVPYNPYLSKKFKAHINVECCQSVKAIKYINKYVYKSSDRTTLKLSDTENEGGRHLQVCFSEDATSSELQHTLANSRSMLMAYFHYYQNNSTAQKDLYQDFSQYFVWNKKDKVCKHRQRGFAIGRLDQSFFEELQTVDGAQCETFMQACLKLHLIEDDQELSHCFDEAVMFSTGSSLRNLFVTALTFGQLLYLALLWEELCDVVYDDLAHKLQTLFPDQLHEKYTVTDDSLFYKGRSEWDYGLFLLDEKLGHLGSSLETCQMPSYKNDWTNDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MV69</accession>
    <name>A0A1C7MV69_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_11208</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001778">
        <property type="protein sequence ID" value="OBZ80743.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="InParanoid" id="A0A1C7MV69"/>
    <dbReference type="OrthoDB" id="10627792at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ80743.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="105" mass="11563" checksum="D80298189A2D9648" modified="2016-11-30" version="1">MSTSSTPHTSFELSANGKLIKCVCTECQESIPLGYDLLTKRTHRMHQDRXNAKKPRIESPSSSQALTSGVIFAFNDLLVEEDEGFSFSETPLEVASVATMQAEKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MVA4</accession>
    <name>A0A1C7MVA4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Transposase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_11179</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001750">
        <property type="protein sequence ID" value="OBZ80772.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MVA4"/>
    <dbReference type="STRING" id="101091.A0A1C7MVA4"/>
    <dbReference type="InParanoid" id="A0A1C7MVA4"/>
    <dbReference type="OrthoDB" id="2287981at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="454"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ80772.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="454" mass="52431" checksum="75E887B6BDA0EA75" modified="2016-11-30" version="1" fragment="single">MLTSLFNRTNNASRNDSQANEVGYIFHLSCVEVRNKAERNALVEDITQERNEELILEPIEDLVEGSVEDQVEDQVEDQVGDQVKDPDVEEVSDTLLDNSVLTEYFEGLQARLANEEYPSKYNNDTFWIEPLMTYFALQKKKKDANYLVLEEIAGRASKGYNKKPHARRIVDMSGCFYLMSVRYRCSNRKCGASFNAHDFEIIEQPSLELQVEFLLSLPIEEVYRKQLPTFSDPVFRTRLDQKGFKRYFESFTCFVMTGLSFSICSLSIASKKYAGFVPTDTVYTEIIKVLQSKIYKHMMLLDGKILKGDHSFKFPKHMAKIDDTSMFTGLYTMTNEYEEIVHQVLVPLKALSYLKHSFENMREAYFDYRHQMPVAFFTDNVKGNQSFAEGIFESLKEGVEPADLERMNTLSTDSSTYLQLPSEINVLYLCRDFDTMEISLRSLLEEIKPPTEDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MVL6</accession>
    <name>A0A1C7MVL6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_11462</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01002061">
        <property type="protein sequence ID" value="OBZ80489.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MVL6"/>
    <dbReference type="STRING" id="101091.A0A1C7MVL6"/>
    <dbReference type="InParanoid" id="A0A1C7MVL6"/>
    <dbReference type="OrthoDB" id="2267579at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="158"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="199"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="204"/>
            <end position="218"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ80489.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="233" mass="26141" checksum="F1354122CB35E518" modified="2016-11-30" version="1">MQRFQREVLRYEGGQWTKEGPINKIFILYCKKYNIDSYQFILNKYKDAEKLTSMAKGGSEIFQDLQHLIERGGGDEDEILQIMKKARRLSVYGFASAKAIDNDAKTVATKALEVLENLIALGKDEEDEDKELAFSSEVVQRIQKAIYDDKIIRGSQASASRSGGFANGGFRGPQNNRGRGSYSCNNRGGFCGGRGETFRERGKSFNSPAENDSSFQHQLGNSLINLDQKILKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MVU7</accession>
    <name>A0A1C7MVU7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Retrotransposon gag domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_11001</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001579">
        <property type="protein sequence ID" value="OBZ80950.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MVU7"/>
    <dbReference type="InParanoid" id="A0A1C7MVU7"/>
    <dbReference type="OrthoDB" id="2285432at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="22"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="22"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="424"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ80950.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="424" mass="46999" checksum="12B05452EC557BE0" modified="2016-11-30" version="1" fragment="single">MSASEQSVNSPIAAVEAGVASSSSSVTSPFASPVVPLAEPTESNQDVDMNAPVEEPKKDVMININVKLTTAFLLESAQKDFAKKRNMYLIAVGDYLALSNKNPDSEDAKLAFIEQERLKKIMKDAENILESIKTMNSPPSSGQDDKKSTMVPVGLPFLQLTSDRVIKSNKESFDSAYDFCQEFEMVLEADSLSLDDSWERLLPMCLNKEERSWFEDKLKNRNYNWKTAEGILLDHIDTPFRKFLNMGRVWCMKQGKGESARTFGAKFQKARRQACLEDEVRESCLIPLSVNYGTKMPSKIEDVIALVSATTSDSTFLLENPGEAKAVAGWNSFAAGHGTPNLDKKGKKRAFVGEDTDKSKKSWNLSQAKKKKVCFGCRAPWSPGHSCPERERKIQEKVSHMAIRSGGEATHDDNTSALANMALD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MWS6</accession>
    <name>A0A1C7MWS6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_10698</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001325">
        <property type="protein sequence ID" value="OBZ81253.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MWS6"/>
    <dbReference type="InParanoid" id="A0A1C7MWS6"/>
    <dbReference type="OrthoDB" id="2246723at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="300"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="305"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ81253.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="480" mass="54344" checksum="FCECFE7C337A376E" modified="2016-11-30" version="1" fragment="single">KNLSTYINQHDRPCLENWINSNLLQFVQHECDSTVQLKNNIVNVWQKFAKDKETNKSLSDNLLNNIFLMKTQTSASQRESIMLWFYSLCENNDVEDVWKRVQGDIENLQKIKTKNPACMLDLVAVRLLHKFNDLTKDEFVALKLAISRIVDFLNDDILDVFKNYVDPFFWEVIKVDEDAAAVSATAATEEEVELVKSVFGPVIEVSKSNEQGVEQAQILIAEKKISLLKENKRQSLEYNLVLAADFIFNNIEDWGSSEITEAQVVANISVILNNIFKNTKLKIVIGEIGAECTKETRKSHETSFSGGCSSSAYTGSATSSKRSKNICGRKADLAVRGEEGVELALCEFKAGRDASTLKKQEGKNLRYNQCVLEALKEYGLNRKIIAFNWGENCGEMFSLEEIEGVFLATSINKQLILPDDPRLLNQAFVDTMIAFCAWRRHLVALNEEAFVARRMRGVGSSKKRKSFVTSFSPKWEANKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MWX0</accession>
    <name>A0A1C7MWX0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DDE-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_10651</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001292">
        <property type="protein sequence ID" value="OBZ81300.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MWX0"/>
    <dbReference type="STRING" id="101091.A0A1C7MWX0"/>
    <dbReference type="InParanoid" id="A0A1C7MWX0"/>
    <dbReference type="OrthoDB" id="2392502at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004875">
        <property type="entry name" value="DDE_SF_endonuclease_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03184">
        <property type="entry name" value="DDE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DDE-1" evidence="1">
        <location>
            <begin position="1"/>
            <end position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ81300.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="168" mass="19652" checksum="F592BC2FD4C98DF9" modified="2016-11-30" version="1">MTKAIFANYFRVFNTKMELTRRKVLVLLNNASVHDNKLRYSSIEFLYLPPNTTTHLQPLDAGIIASFKKQYRKLQYTAVAVKYRIAVMNDKLSDKINWTLRDRYNLSLPADRRSNKKKNFFHLDQLQGMQDIKRACRSVSSETISNRYLHTGLFESLNNSSEVRKVAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MX58</accession>
    <name>A0A1C7MX58_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Sporulation protein RMD1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">RMD1_2</name>
        <name evidence="5" type="ORF">A0J61_10592</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the RMD1/sif2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001253">
        <property type="protein sequence ID" value="OBZ81361.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MX58"/>
    <dbReference type="FunCoup" id="A0A1C7MX58">
        <property type="interactions" value="18"/>
    </dbReference>
    <dbReference type="InParanoid" id="A0A1C7MX58"/>
    <dbReference type="OrthoDB" id="18302at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003734">
        <property type="entry name" value="DUF155"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051624">
        <property type="entry name" value="RMD1/Sad1-interacting"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16255">
        <property type="entry name" value="REQUIRED FOR MEIOTIC NUCLEAR DIVISION PROTEIN 1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16255:SF15">
        <property type="entry name" value="SPORULATION PROTEIN RMD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02582">
        <property type="entry name" value="DUF155"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="385"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="domain" description="DUF155" evidence="4">
        <location>
            <begin position="186"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="23"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="40"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF02582"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OBZ81361.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="414" mass="47819" checksum="C04F99C5E2B697C4" modified="2016-11-30" version="1">MSQRPHTMHKGDEEEEAAPLLISPESPSTSAPRPTASRSYTQRSSYYNTFNNDKSGRVTKPKQPMRTTKISQKLKLFPEDEALLPEEGEEDADVYTQLAKIPHGMERQEAEMLNKMDRSELSRMTAYCTASAYRMDGLFKFLQSKRKTNGTAPQRFDECLYTPYAFTYPAAPPNNITSKAQKLPEMFLFDYGVVVFWGMTLKEEQRILKFLVSFEEEKLDVDDVETEEFHYYYNETYQPRIYNDIITLRHPSNYLIKLTISHAIAQSVKMTLFERLIDDTINETKYIPQVMAESGNIHMSRTAITKKIGELFIMRINVNLVSNILDTPEIFWSEPTLEPLYSAIRGYLEIEQRVQLLNQRVEVISDLLEMLKDHLNSSHGEALEWIVIWLIGLEILVAVITTSLDAFSLYNGKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MYJ6</accession>
    <name>A0A1C7MYJ6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Nucleolysin TIA-1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">Tia1</name>
        <name evidence="4" type="ORF">A0J61_10041</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001010">
        <property type="protein sequence ID" value="OBZ81910.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MYJ6"/>
    <dbReference type="STRING" id="101091.A0A1C7MYJ6"/>
    <dbReference type="InParanoid" id="A0A1C7MYJ6"/>
    <dbReference type="OrthoDB" id="6159137at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1900.10">
        <property type="entry name" value="c-terminal domain of poly(a) binding protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036053">
        <property type="entry name" value="PABP-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050441">
        <property type="entry name" value="RBM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48034">
        <property type="entry name" value="TRANSFORMER-2 SEX-DETERMINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63570">
        <property type="entry name" value="PABC (PABP) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="3">
        <location>
            <begin position="50"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="9"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OBZ81910.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="483" mass="54191" checksum="C0E4476ACF0907F5" modified="2016-11-30" version="1">MLTAPYVHLNSKKQHGELGRASTDDLSSNHGGMSVVHSNSDSVVSMVDYTNLYIKNLDPEVTSYDLFKSFKDYGRIISARVMRDTMTSISKGYGFVSFSTMEEANEAQQHMNGALINSKHIVVTFHTHKKPANSTKVKNANHHQRLPQQQHVVDYMNLSPPTTASSSNNNTVSMYPIYNSQPSPPYSHHRQNGTMFPPHESYIPAKSNIPPPTNSMATAMTPHHHYAQNPWNETGFWMHPNASNNTSSVKELSPFHYHHLPSMHAPNISQVQTQTTSASALVSPSTDCASPPLIDLGHPYYSDNASTLPSQIQIQKIRDAVSAQLKEDQQKDLNDLVDLIQSLKKRDLSLCLFNPMFLKQKIEEAYEALYLFQNPPQSATPVTSNKMASLLDESNSKMNLSAEQVQAASFILSSLEGMTLNKKKRVFGDIFFPFVRATGVKHAPKVTIRLLDTVPLEELAYNMYDKPELTRKAQYIYNELYSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MYT7</accession>
    <name>A0A1C7MYT7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Sister chromatid cohesion protein DCC1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">DSCC1</name>
        <name evidence="3" type="ORF">A0J61_10011</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the DCC1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001001">
        <property type="protein sequence ID" value="OBZ81941.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MYT7"/>
    <dbReference type="FunCoup" id="A0A1C7MYT7">
        <property type="interactions" value="323"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7MYT7"/>
    <dbReference type="InParanoid" id="A0A1C7MYT7"/>
    <dbReference type="OrthoDB" id="276989at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000785">
        <property type="term" value="C:chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000775">
        <property type="term" value="C:chromosome, centromeric region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031390">
        <property type="term" value="C:Ctf18 RFC-like complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034088">
        <property type="term" value="P:maintenance of mitotic sister chromatid cohesion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019128">
        <property type="entry name" value="Dcc1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13395:SF6">
        <property type="entry name" value="SISTER CHROMATID COHESION PROTEIN DCC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13395">
        <property type="entry name" value="SISTER CHROMATID COHESION PROTEIN DCC1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09724">
        <property type="entry name" value="Dcc1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0235">DNA replication</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ81941.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="367" mass="42477" checksum="6C96C166B85D4339" modified="2016-11-30" version="1">MSSSRLIYNHQFEKNAYSLIELSSSELVEAFESGDEIVIKGLPEDEAVLCTNRKTYSVRQVNTSNSMLIVTDDQLDITIHDDLSNTIELIPCLARTSRIDDLLAESSYSGSRNDAHIKSTKTLYTYQDLLSLVQASEGELIDALRMRGAFEHEGYYRLFDREFLFRLFDSLVTNAILHQSDFKHMSLGEAKSCIRDEIGAVDEEEIVPDHVLLASIRMFAQHDVSQDEQILEFDEAKICRFLGEWLLANPRNKRWEMNEFLEVWKKLTQEVFVPKIEYIQGLYVMHTSTKLHQVENFVQYFPVHELSTDPAQRFAALFAEKPLWSLEEITPFLTDLAPQKKDKEHLLLKFARPHRNQTTTLYGSRIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MZ25</accession>
    <name>A0A1C7MZ25_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Guanine nucleotide-binding protein subunit beta-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">cpc-2_2</name>
        <name evidence="5" type="ORF">A0J61_09867</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the WD repeat G protein beta family. Ribosomal protein RACK1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000958">
        <property type="protein sequence ID" value="OBZ82083.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MZ25"/>
    <dbReference type="FunCoup" id="A0A1C7MZ25">
        <property type="interactions" value="778"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7MZ25"/>
    <dbReference type="InParanoid" id="A0A1C7MZ25"/>
    <dbReference type="OrthoDB" id="7875889at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043022">
        <property type="term" value="F:ribosome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045182">
        <property type="term" value="F:translation regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.10:FF:000039">
        <property type="entry name" value="Guanine nucleotide-binding protein subunit beta-like protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045223">
        <property type="entry name" value="RACK1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19868">
        <property type="entry name" value="RECEPTOR FOR ACTIVATED PROTEIN KINASE C RACK1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="6"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 4" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="10"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="58"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="100"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="143"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="187"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="288"/>
            <end position="316"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007253"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OBZ82083.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="316" mass="35121" checksum="BD8AB51CF5AEDE06" modified="2016-11-30" version="1">MDTLTLRGTLEGHGNWVTAIATTSEAPDMVLSASRDRSIIVWNLTRDEMNYGVPRKSLVGHSHFIEDIAISSDGQFALSASWDQTLRLWDLNSGTTTRRFVGHKNDVLSVSFSADNRQIVSGSRDKSIKLWNTLGECKYNITEDGHTEWVSCVRFSPNPANPVIVSGGWDKLVKVWDLTKLKLRTNFIGHNGYVNTVTISPDGSLCASAGKDGVVMLWDLNDAKHLYSLEAGSNVHALTFSPNRYWLCAATANGIKIWDLESKSIVDELRPEFPQLGKRKNPDPECLSVCWSADGATLFSGYTDNIIRVWQVTRTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MZ61</accession>
    <name>A0A1C7MZ61_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">A0J61_09843</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the WD repeat ESC family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000952">
        <property type="protein sequence ID" value="OBZ82107.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MZ61"/>
    <dbReference type="STRING" id="101091.A0A1C7MZ61"/>
    <dbReference type="InParanoid" id="A0A1C7MZ61"/>
    <dbReference type="OrthoDB" id="7318948at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051243">
        <property type="entry name" value="PcG_WD-repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10253">
        <property type="entry name" value="POLYCOMB PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="4" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="2 6" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="2"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OBZ82107.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="288" mass="32342" checksum="3181B4E4E8C64A9E" modified="2016-11-30" version="1" fragment="single">YLFGHRQPVLKLVFSKSEPRWLFISDHRVLGVSADNTVRLWDVGSPTSRTDDSMCLAKFTLPTDVGVPSTLSVSYDLSTVIVGCDNGDMVRYDLSDKILVKLRQKMEQAKKQDAAEKWFNPMTVESTMTYPSGDEWHAGYVDDICILGQDGDTKNPLYNKVLSRGANDLEILLWNPDESTPKDAEIEKSFDWPDSAECTGLRFKVVEREDTKALIAGEYEGQIHIYNISDGKKSKMLDDGSMELFHPTTVLSHPKSSQLIRDVCCSTDTRTIVAVDNNNTAFVWTTVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MZA0</accession>
    <name>A0A1C7MZA0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Replication factor A protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">ssb1_0</name>
        <name evidence="9" type="ORF">A0J61_10216</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the replication factor A protein 1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001075">
        <property type="protein sequence ID" value="OBZ81736.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MZA0"/>
    <dbReference type="STRING" id="101091.A0A1C7MZA0"/>
    <dbReference type="InParanoid" id="A0A1C7MZA0"/>
    <dbReference type="OrthoDB" id="1751331at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04474">
        <property type="entry name" value="RPA1_DBD_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd04477">
        <property type="entry name" value="RPA1N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.140:FF:000041">
        <property type="entry name" value="Replication protein A subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.140:FF:000117">
        <property type="entry name" value="Replication protein A subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004365">
        <property type="entry name" value="NA-bd_OB_tRNA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007199">
        <property type="entry name" value="Rep_factor-A_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47165">
        <property type="entry name" value="OS03G0429900 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47165:SF4">
        <property type="entry name" value="OS03G0429900 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04057">
        <property type="entry name" value="Rep-A_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01336">
        <property type="entry name" value="tRNA_anti-codon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Replication factor-A protein 1 N-terminal" evidence="8">
        <location>
            <begin position="4"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="domain" description="OB" evidence="7">
        <location>
            <begin position="181"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="115"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="117"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="323"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005690"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF04057"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OBZ81736.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="323" mass="35197" checksum="4B306B6F63CA5EBA" modified="2016-11-30" version="1" fragment="single">MVQLTSGSIKALSENDKNSPAYNNPVVQLINIKPVNVNGSIRHRVIVSDGDHFMQGMLAVHHASAVDDGTIKKMCILRLTESVCNPLNNRKILVVLNFDVLQSDVDAKIGSPVSIDTIPTNDNTSTATSAPASNFSTTRPETSSSSSGYGNQAGFSSSANLQLEANLTPIRNLNPYQTRWHIKARVSQKSPIKEWQNAKGGGQLFSVNLLDQTGEIKATAFGDQVTRLYHVLEEGKVYYISKARVTMARKQFSNLNNEYELGLEPNTEIEACPEPGNIPMMNFDFVKIGDLVKREANSYVDVLGVVTEDAGLSEIISKATGKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MZA1</accession>
    <name>A0A1C7MZA1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_09764</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000930">
        <property type="protein sequence ID" value="OBZ82190.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MZA1"/>
    <dbReference type="InParanoid" id="A0A1C7MZA1"/>
    <dbReference type="OrthoDB" id="2260217at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ82190.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="737" mass="84966" checksum="3233BFD9D61C9F70" modified="2016-11-30" version="1">MERITTTVSMQDTLSWDPSAHYLLAHCSIHDLSIAIDHQGRCYGLPSKDVCLPESVHAIVNHCRHGSDQCRFYILTHSHDLYQWDIESRCSCPYESQEMPRKKRVRLIEEEEKMDIDMHGLSKISSHVVHIMTYLPNQLVLFSKTEDVRLLDTASHHLSTSTPFAFKDRYVTAHLPVECLSEAFVDFFQLKERQGIMLAKQDSTIYWRNSSEDTKLFSMESHEQIEWIDYDTNQLVALGGDIITDSLLQRNQGTIVLYFYSNKGIQHQQFHLNGTIQALTKINAFHYLVATGLGRVYRLYVEQTEMKYIPMQGLSNVILLASDHHDSFRAITVDPDQQQAHLLQVNYNPMPVSLEDDPKALKESIQQTLRELAQSESLVRQMDLKEQALNQKLTSINRTLYAIQSIHQKRKIGQCNSIETTGFEYTIQPIVQSNSSEHTLFQTTAHVRVCLKTARFLELEDWTLQLHFSKTGLVRRIPVVGLESCFENQMERYSVWEHNLPIDSTQLPCQVDSMLMIDLSPDPAACFALSTIPLDEFHFAVPLHESLNANIQRRGLEEVSDRLMKSWQQRQSRDNTAAHPFARWMKKRQNNQPSNMKEERGLDLGVVRMRYRVDTTFSAEDYRSILSLILGEGRTIDDMKRILYGGAEHASFVLAFYPACPILLDLSRVSDTMIEFKIQCHSMPVLSRAETTLLERIRFYGLSRPLESQPIDQTLNSVQPSYRLDSDIPIGHFKIEH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MZI4</accession>
    <name>A0A1C7MZI4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_10123</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001043">
        <property type="protein sequence ID" value="OBZ81829.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MZI4"/>
    <dbReference type="InParanoid" id="A0A1C7MZI4"/>
    <dbReference type="OrthoDB" id="2279623at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="73"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="9"/>
            <end position="18"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ81829.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="91" mass="10429" checksum="4B734FE87D666A03" modified="2016-11-30" version="1">MAQQKSDSKSSSTVSTSVPYYGSREPKQSVIETDKLIFEMMDDMSKMAKKQSTQEQQEQEELEAQKDIPITTWRTRIILVSFIIILLVIGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MZN4</accession>
    <name>A0A1C7MZN4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_10066</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001020">
        <property type="protein sequence ID" value="OBZ81886.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MZN4"/>
    <dbReference type="STRING" id="101091.A0A1C7MZN4"/>
    <dbReference type="InParanoid" id="A0A1C7MZN4"/>
    <dbReference type="OrthoDB" id="2248168at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ81886.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="190" mass="21159" checksum="C64AB36D88EC8E44" modified="2016-11-30" version="1">MALSTTDPNHIRKVDGISTEVSSSTHNPNNQSFTFRIWAQMVKVQKRQPLSLTENASFPDESSSMSTTIFLQATEDYSIAIDAKQFEGINFSSRSLNLVLRDQFPKGVGLRDRRVGRTQRYIEIGFETAADRLEALSAPFKLQDDLIKMSATMDGNAQVVGIGISNIPFGTAATLQPRLLEIFHQFGNWS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N0K7</accession>
    <name>A0A1C7N0K7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">DUF3835 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">A0J61_09312</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the RNA polymerase II subunit 5-mediating protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000821">
        <property type="protein sequence ID" value="OBZ82640.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N0K7"/>
    <dbReference type="STRING" id="101091.A0A1C7N0K7"/>
    <dbReference type="InParanoid" id="A0A1C7N0K7"/>
    <dbReference type="OrthoDB" id="21413at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003682">
        <property type="term" value="F:chromatin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019212">
        <property type="term" value="F:phosphatase inhibitor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003714">
        <property type="term" value="F:transcription corepressor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000122">
        <property type="term" value="P:negative regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd23159">
        <property type="entry name" value="Prefoldin_URI1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.370">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024325">
        <property type="entry name" value="DUF3835"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009053">
        <property type="entry name" value="Prefoldin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004127">
        <property type="entry name" value="Prefoldin_subunit_alpha"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052255">
        <property type="entry name" value="RNA_pol_II_subunit5-mediator"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15111">
        <property type="entry name" value="RNA POLYMERASE II SUBUNIT 5-MEDIATING PROTEIN NNX3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15111:SF0">
        <property type="entry name" value="UNCONVENTIONAL PREFOLDIN RPB5 INTERACTOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12927">
        <property type="entry name" value="DUF3835"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02996">
        <property type="entry name" value="Prefoldin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46579">
        <property type="entry name" value="Prefoldin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF3835" evidence="5">
        <location>
            <begin position="621"/>
            <end position="706"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="218"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="413"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="507"/>
            <end position="533"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="676"/>
            <end position="695"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="241"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="251"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="277"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="308"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="330"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="413"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="458"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="512"/>
            <end position="532"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00038295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF12927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OBZ82640.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="717" mass="82503" checksum="503EFAA83F219B15" modified="2016-11-30" version="1">MTDLSSQISLFSSHLDEQLEKLENEYQRWTHYKNDYDALERQLLTLPDTTSKQAMIPIGKLAFMPGKIVHTNEILVLLGDQYYAERSAKQAVNILGRRKEVVMENMRLAEAQLNSFKTKKDTLTEASGTLTPSGQQLNEEGLPIMEIREELPPLQEEKKAIEPKEKAIEPKQQPLEGLPESVLRARSMMKEADEKIKGAIEDSENKALFDLLRELEEEEEEEEKIEDVRHRKNPIQMTVKEAVEYKNNRDSEDDDDDDEEDGRYDTEIADNMFDRFGDDEEYGLDGVVDQEDFTHYEQEVSQVSLDRDDFDYEDEDEKSTPKVITKKKAKPVEEKPIHEKPVNDKPINDKPIKDTPIQEKSIEDKPVIIEPKAKKLSKFKQAQLEKKTEAKIETKADKETEEKPKKFSKFKLLRQEQKQRPTRAIVEETKEQETVPTIVPSPVQTTLPEETAEYTEPKPTQNRQIPNVATQKKKPSRFKSERTAVAIEKPKRTVTWDTTTTVRDHDALSAPSAVSTTDSYSQPMKSEPTKTIRSPADIFRVIRQTQQDGYPSLEEDGDVDVDLNQLIQVARETKEPFYRSADGSDVPMLTPPPPPIILMSEEEQQVVPRKSKLDNKVMKGAVMERDIVPVDFEQVEEEMDLREITSNYQQKRQSMLAATGGFSFDMKPEFEVFDEELPLPKRDKQADDEEEEVAPKKISRFKAARLGMSFNNEESLY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N0R2</accession>
    <name>A0A1C7N0R2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_09263</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000810">
        <property type="protein sequence ID" value="OBZ82690.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N0R2"/>
    <dbReference type="STRING" id="101091.A0A1C7N0R2"/>
    <dbReference type="InParanoid" id="A0A1C7N0R2"/>
    <dbReference type="OrthoDB" id="2288618at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ82690.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="129" mass="14723" checksum="A7C98FF80055BD8D" modified="2016-11-30" version="1">MFVKCYQLVIDDNTPAVYLSEVEVHVPVLQLQSIVFVDRNRPVLQLDGTMVSSKFFKLFTAQHHLKKQVEGSSGKYYKVKISPIILFTDDTSGNSSKQFNAYESWSMRCASMSFKDRSSIENFHFLGAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N0V9</accession>
    <name>A0A1C7N0V9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Cell division cycle-related protein res2/pct1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">res2_3</name>
        <name evidence="7" type="ORF">A0J61_09311</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000821">
        <property type="protein sequence ID" value="OBZ82638.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N0V9"/>
    <dbReference type="STRING" id="101091.A0A1C7N0V9"/>
    <dbReference type="InParanoid" id="A0A1C7N0V9"/>
    <dbReference type="OrthoDB" id="6718656at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030907">
        <property type="term" value="C:MBF transcription complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033309">
        <property type="term" value="C:SBF transcription complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001228">
        <property type="term" value="F:DNA-binding transcription activator activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.260.10:FF:000001">
        <property type="entry name" value="APSES transcription factor (MbpA)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.260.10">
        <property type="entry name" value="Transcription regulator HTH, APSES-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036887">
        <property type="entry name" value="HTH_APSES_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018004">
        <property type="entry name" value="KilA/APSES_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051642">
        <property type="entry name" value="SWI6-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003163">
        <property type="entry name" value="Tscrpt_reg_HTH_APSES-type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43828">
        <property type="entry name" value="ASPARAGINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43828:SF3">
        <property type="entry name" value="CHROMO DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04383">
        <property type="entry name" value="KilA-N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM01252">
        <property type="entry name" value="KilA-N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54616">
        <property type="entry name" value="DNA-binding domain of Mlu1-box binding protein MBP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51299">
        <property type="entry name" value="HTH_APSES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="7" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="7" id="KW-0132">Cell division</keyword>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="HTH APSES-type" evidence="6">
        <location>
            <begin position="6"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="200"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="314"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="115"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="443"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="517"/>
            <end position="558"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="451"/>
            <end position="463"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51299"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OBZ82638.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="623" mass="69992" checksum="6F0FDF24D93E7DE1" modified="2016-11-30" version="1">MVEGNIYTAVYSSVPVFEMIVKGIAVMRRRTDDYMNATQILKVANIEKGKRTKILEKEVLVGEHEKVQGGYGKYQGTWIPFNKSKELAERYGVANLLAPMFNFDLVKIPMDEQQTLPQPEEQEKETTKTDNPPSPEIPPSKKAKLGSPDSVEANTMTMTEHNRSVLMSIFLSDKPDQIREFLEQSDNQESFIVDMVIDEQGNTALHWAASLARINTVELLVEKGANIACTNYAGETPLMRSVMVTNNYDMQSFPRVFELLKSTVHMTDHKKRTVLHHAALTGSIQGRAEAATYFIQHLVSKEVCKLILDAQDSLGDTALSIAARLESTGLADALIKAGATQNTQNHAGLDIQDYKDKVTEDITMEEAPSSSAKSSQRVFSNTSLYSKKPYAPSQRGKEIVATVQKIVDALDEEYGSQLTSKEQELQAVQEDLNAVSQELEKTRKSLEERQTQSQRLSEAQQKTRNLDNALQTGWQRLESLMQASGRHVLTQQDLDRFDEHTDIDAHLDDIGLPTDDKDLLDQQIRRARAKVKAYEANNKALDQEIMEIEHQYTEKEMQCKRLIAACCNLPIDKIDDLVEPLTLAIESDPPDLDLARVIGFMDKIRRQGAFTEPPMNPPKSTPH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-06-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N0W0</accession>
    <name>A0A1C7N0W0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_09279</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000815">
        <property type="protein sequence ID" value="OBZ82671.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N0W0"/>
    <dbReference type="InParanoid" id="A0A1C7N0W0"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ82671.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="54" mass="6037" checksum="900A30ECB50C385A" modified="2016-11-30" version="1" fragment="single">QKLTTTEKDTTSGVEAEATTIVVGTNHNNQVAEAKTKDVVWSHPWLTYFKKFGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N162</accession>
    <name>A0A1C7N162_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">40S ribosomal protein S12</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">RPS12_0</name>
        <name evidence="6" type="ORF">A0J61_09127</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the eukaryotic ribosomal protein eS12 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000780">
        <property type="protein sequence ID" value="OBZ82822.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N162"/>
    <dbReference type="FunCoup" id="A0A1C7N162">
        <property type="interactions" value="542"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N162"/>
    <dbReference type="InParanoid" id="A0A1C7N162"/>
    <dbReference type="OrthoDB" id="10249311at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022626">
        <property type="term" value="C:cytosolic ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015935">
        <property type="term" value="C:small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1330.30:FF:000005">
        <property type="entry name" value="40S ribosomal protein S12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029064">
        <property type="entry name" value="Ribosomal_eL30-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004038">
        <property type="entry name" value="Ribosomal_eL8/eL30/eS12/Gad45"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000530">
        <property type="entry name" value="Ribosomal_eS12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047860">
        <property type="entry name" value="Ribosomal_eS12_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11843">
        <property type="entry name" value="40S RIBOSOMAL PROTEIN S12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01248">
        <property type="entry name" value="Ribosomal_L7Ae"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00972">
        <property type="entry name" value="RIBSOMALS12E"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55315">
        <property type="entry name" value="L30e-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01189">
        <property type="entry name" value="RIBOSOMAL_S12E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 6" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Ribosomal protein eL8/eL30/eS12/Gadd45" evidence="5">
        <location>
            <begin position="27"/>
            <end position="121"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OBZ82822.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="142" mass="15644" checksum="E2D68B79BAFF2A2A" modified="2016-11-30" version="1">MSDHEEVIAQEVEVAVEATSGQMSVEDALQEVLRRALVHDGLARGLKEAVKALDRRQAHLAVLVETCTESEYIKLVEALCSEHNINLIKVSDAKKLGEWAGLCKIDREGNARKVVGCSCVAVTDFGEESEAMNVLLDYFKTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N1M1</accession>
    <name>A0A1C7N1M1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Putative 6-phosphofructo-2-kinase PB17E12.14c</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">A0J61_08958</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000743">
        <property type="protein sequence ID" value="OBZ82992.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N1M1"/>
    <dbReference type="FunCoup" id="A0A1C7N1M1">
        <property type="interactions" value="355"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N1M1"/>
    <dbReference type="InParanoid" id="A0A1C7N1M1"/>
    <dbReference type="OrthoDB" id="267323at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003873">
        <property type="term" value="F:6-phosphofructo-2-kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006003">
        <property type="term" value="P:fructose 2,6-bisphosphate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006000">
        <property type="term" value="P:fructose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07067">
        <property type="entry name" value="HP_PGM_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000644">
        <property type="entry name" value="GpmB, Fructose-2,6-bisphosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1240">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003094">
        <property type="entry name" value="6Pfruct_kin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013079">
        <property type="entry name" value="6Phosfructo_kin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013078">
        <property type="entry name" value="His_Pase_superF_clade-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029033">
        <property type="entry name" value="His_PPase_superfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001345">
        <property type="entry name" value="PG/BPGM_mutase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10606:SF32">
        <property type="entry name" value="6-PHOSPHOFRUCTO-2-KINASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10606">
        <property type="entry name" value="6-PHOSPHOFRUCTO-2-KINASE/FRUCTOSE-2,6-BISPHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01591">
        <property type="entry name" value="6PF2K"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00300">
        <property type="entry name" value="His_Phos_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000709">
        <property type="entry name" value="6PFK_2-Ptase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00991">
        <property type="entry name" value="6PFRUCTKNASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00855">
        <property type="entry name" value="PGAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53254">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00175">
        <property type="entry name" value="PG_MUTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="6-phosphofructo-2-kinase" evidence="4">
        <location>
            <begin position="101"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="8"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="28"/>
            <end position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01591"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OBZ82992.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="553" mass="64242" checksum="ADE21F852441183B" modified="2016-11-30" version="1">MHHHNDRRKTLPEVKPEKDDQENLSKRVLTNLSTKENPSENDTQIAHTSKLNPPKAIPSWLQAQHTKESSTKTSNIRHSIGLDVPGAVHTIRTPKLKTERQLDSKLVVIMVGLPARGKSYIVKKLRRYLNWLQYETKIFNVGNMRRVYESSQEQNANFFDPSNPDSKRIRDEIALGVLDQLIDWLKEGGRVAIHDATNSTVARRKLLIDRLAKEPEIRILMIESVCTDHTMLERNFRLKLSGPDYKNKDPTEALSDFRSRVANYEKAYEPVGEWEEENDIQFCKLINVGKKVIAYNISGYLSGQCIFYLMNFNLNERQIFVTRHGESEDNVTGRIGGDADLSPKGRKFAKALAKFVQTQRIRFGCELAAKANELEPEEKQTPALALQKTAEYCNSQFSVWTSMLKRSKQTAEHFDPDDYDIKHIRFLNEINSGVCEGMTYQEIQEKHPSEYKSRQQNKLFYRYPGMGGESYIDVIHRLQPMIVELERMTQSCLIITHRVVMRILLGYLLDWTREEMPHMMVPIHTVYELRPKPYGTELKKWQYIEETDTFVEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N389</accession>
    <name>A0A1C7N389_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Nitrogen regulatory protein areA GATA-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_08484</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000658">
        <property type="protein sequence ID" value="OBZ83468.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N389"/>
    <dbReference type="InParanoid" id="A0A1C7N389"/>
    <dbReference type="OrthoDB" id="5563539at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052292">
        <property type="entry name" value="Glucose_repression_reg"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28051">
        <property type="entry name" value="PROTEIN MTL1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28051:SF1">
        <property type="entry name" value="PROTEIN MTL1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ83468.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="259" mass="29989" checksum="EA210A4E61670840" modified="2016-11-30" version="1">MTAEHCVDYLSHQWTCDDLILTYRQMHQQNLSPMESEQNKTIRLRNALWRSMARCCISHLGKSNALIDPSTVYWQKESDITWLYGPIYTNHSAELDNRHGTSVLQGLKPVLKKHCNVAQILPNCSDPILSYFDSSVLYTHTPISQSSRSSSFSSFSSKSSVGVHFNPEIIEIEYQPEYPVASRLMEEEEDYDLVDFFWSLLIQAILSMKSRLMFCRPYSVIMMTKSVLATTWFLYQNLLPISWIIKKPFAGHKKHISHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N3Q8</accession>
    <name>A0A1C7N3Q8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Very-long-chain 3-oxoacyl-CoA reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">A0J61_08194</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000609">
        <property type="protein sequence ID" value="OBZ83753.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N3Q8"/>
    <dbReference type="STRING" id="101091.A0A1C7N3Q8"/>
    <dbReference type="InParanoid" id="A0A1C7N3Q8"/>
    <dbReference type="OrthoDB" id="153074at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05233">
        <property type="entry name" value="SDR_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42901">
        <property type="entry name" value="ALCOHOL DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42901:SF1">
        <property type="entry name" value="ALCOHOL DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="7"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OBZ83753.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="318" mass="34614" checksum="C476460AEF1FBA71" modified="2016-11-30" version="1">MFFITSFFYWVGVLTLVPYLLLVAYGAYGCPEQNLKTKYNAKWALVTGGSSGIGAAIVRKFASQGLNVVVVALNDAVLEAFKETIAKEYPQVEFRFVGCDLSNANGNYLESIKQVTNDIDVQILCNNAGFITTGGFADVPFERDMANFHTNVTSGLTLTHYFADQMLNKGLRGLITFTSSSAAFIPNPMSALYASTKIFLTTFAASIAAELAEAKIDVLAIHPSPINSNFYSNAGKMSALLSAQKLSSPPSVIADTICRNAGKVVIADQGPITVVMRILTTKLMDWNVFTEIMKLGLRYNGDYKAMKVIRSVQAKKEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N483</accession>
    <name>A0A1C7N483_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Glutaredoxin-3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">glrx3</name>
        <name evidence="7" type="ORF">A0J61_08125</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Monothiol glutaredoxin involved in the biogenesis of iron-sulfur clusters. Binds one iron-sulfur cluster per dimer. The iron-sulfur cluster is bound between subunits, and is complexed by a bound glutathione and a cysteine residue from each subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the glutaredoxin family. Monothiol subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000598">
        <property type="protein sequence ID" value="OBZ83828.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N483"/>
    <dbReference type="FunCoup" id="A0A1C7N483">
        <property type="interactions" value="489"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N483"/>
    <dbReference type="InParanoid" id="A0A1C7N483"/>
    <dbReference type="OrthoDB" id="415696at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015036">
        <property type="term" value="F:disulfide oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006879">
        <property type="term" value="P:intracellular iron ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd03028">
        <property type="entry name" value="GRX_PICOT_like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="CDD" id="cd02984">
        <property type="entry name" value="TRX_PICOT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.30.10:FF:000012">
        <property type="entry name" value="Monothiol glutaredoxin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.30.10:FF:000092">
        <property type="entry name" value="Monothiol glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002109">
        <property type="entry name" value="Glutaredoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033658">
        <property type="entry name" value="GRX_PICOT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004480">
        <property type="entry name" value="Monothiol_GRX-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00365">
        <property type="entry name" value="Grx4 family monothiol glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10293">
        <property type="entry name" value="GLUTAREDOXIN FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10293:SF73">
        <property type="entry name" value="GLUTAREDOXIN-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00462">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00085">
        <property type="entry name" value="Thioredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51354">
        <property type="entry name" value="GLUTAREDOXIN_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0408">Iron</keyword>
    <keyword evidence="4" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin" evidence="6">
        <location>
            <begin position="1"/>
            <end position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00055846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OBZ83828.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="333" mass="37137" checksum="BF1FCCFA971A4BFD" modified="2016-11-30" version="1">MSNLVEITSEAQFHDILAKKDAVHVLNFWAPWAEPCQQMNEVFAELAGKFPALQFLKIEAEEYPDISENYEIAAVPTFIIVKAGKVAEQVEGAKAAELSNAVAKHAKGVLNRFTSPSVAATENGNAVKPVKDLNARLKALVNSAPVMIFIKGTPQQPRCGFSRQLVELLGEQKVKYSSFNILADEDVRQGLKAFSDWPTYPQVYINGELMGGLDIIKEMVASGEFKDVLPKEKDLSTRLQELIEKQPVMVFIKGTPEEPRCGFSRQLVALLNERHVKYGHFDILSDEEVRQGLKVHVDWPTFPMLFYKGELLGGLDIVKEMIESGEFDQVLTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N4L5</accession>
    <name>A0A1C7N4L5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_07985</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000577">
        <property type="protein sequence ID" value="OBZ83967.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N4L5"/>
    <dbReference type="STRING" id="101091.A0A1C7N4L5"/>
    <dbReference type="InParanoid" id="A0A1C7N4L5"/>
    <dbReference type="OrthoDB" id="1600564at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1110">
        <property type="entry name" value="SGNH hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036514">
        <property type="entry name" value="SGNH_hydro_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="332"/>
            <end position="357"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ83967.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="376" mass="42799" checksum="A48B02546B62913C" modified="2016-11-30" version="1">MATAVKNLVVFGDFNPDHPNWSEYLALGWNASLYSFAFSGSVCDHNLYGSTSDIPSLKDQLEAYYTLRLNLKPEETVYAFWIGTQDVLDMGRHVGKANCEITQAIIKRTHLMIGQHEIDVKKVTDCIVQQLKAALKVFLSDRFLVFNIPPIEYMPLKSTSALNQSQAAVEINRGLERDVANLNKHHYALKMDYMDIHSLVHDIVADPALFQLTEPPYLDRCSGQKQCGSGEHDGLRWDKTQFTLGFHQKVAEGILEAESYMPKIELTEEWMEQLNDPQSRFHSKKYKVRPAKGIVDEQARLYDMEKSSPIQPQQPPLEDEPEMVAAKSHVHLIGLLALLLVFVGIVWVKSSCLLSFFSRMRNNDRGKFTPVRNEEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N4Y4</accession>
    <name>A0A1C7N4Y4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Aspartate aminotransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">aspC</name>
        <name evidence="7" type="ORF">A0J61_08255</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000619">
        <property type="protein sequence ID" value="OBZ83699.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N4Y4"/>
    <dbReference type="STRING" id="101091.A0A1C7N4Y4"/>
    <dbReference type="InParanoid" id="A0A1C7N4Y4"/>
    <dbReference type="OrthoDB" id="2108at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008483">
        <property type="term" value="F:transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006520">
        <property type="term" value="P:amino acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00609">
        <property type="entry name" value="AAT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004839">
        <property type="entry name" value="Aminotransferase_I/II_large"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050596">
        <property type="entry name" value="AspAT/PAT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46383">
        <property type="entry name" value="ASPARTATE AMINOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46383:SF1">
        <property type="entry name" value="ASPARTATE AMINOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00155">
        <property type="entry name" value="Aminotran_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="5" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotransferase class I/classII large" evidence="6">
        <location>
            <begin position="112"/>
            <end position="457"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OBZ83699.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="468" mass="52392" checksum="87801D159F6A3042" modified="2016-11-30" version="1">MAAEGITNAKNKFLNVVEQVRQQVVAEHDSEAHQVLRSYPGNENKATSAKKKGSVYGIGHPGSTGVIYVMDRAVKNGYTAGDPSWSNFGQGAPEVGPIDGCMERPETIDLPIDAYEYAPTSGIKELRETVANLYNEVYRQGKSSKYTYENVCIVPGGRAGLSRIASVIDDVNVGYFLPEYTAYEQMLSVFKRFVPIPTTLDEESNYHIDAKTICKEIAGRGLGVIVASNPRNPTGQVIQDEELAELVKVAKERHATLVIDEFYSAYIYDKEEGKTISITHFVEDVNEDAVIVVDGMTKNFRMPGWRVCWIVGPKSVITAMESAGSYLEGGANHPLQKAAIPFLDPNKFREEAKALQHHFKEKRDYVLKRLEEMGLKVKVPPKATFYIWLDLSHLPEPINVGLHFFEECLKEKVIVVPGIFFDVNPAHRRELFESPCHHFVRLSFGPPMDQLEKGLDAVQRVIKKFNSH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N512</accession>
    <name>A0A1C7N512_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_07733</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000540">
        <property type="protein sequence ID" value="OBZ84213.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N512"/>
    <dbReference type="InParanoid" id="A0A1C7N512"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ84213.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="97" mass="11267" checksum="1025792F0423E77D" modified="2016-11-30" version="1">MIPSIQNEQDCDPHHFDNGLCKKPHPTSRCQTSFTVKVKSYLCFVNFVGEVKTRFSTLDCYRIGMFSLALYEQNGMESVTSFHTKDLNMTFNVIYFH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N5E6</accession>
    <name>A0A1C7N5E6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Vacuolar proton pump subunit B</fullName>
            <shortName evidence="5">V-ATPase subunit B</shortName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Vacuolar proton pump subunit B</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">VMA2</name>
        <name evidence="9" type="ORF">A0J61_07741</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Non-catalytic subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">V-ATPase is a heteromultimeric enzyme composed of a peripheral catalytic V1 complex attached to an integral membrane V0 proton pore complex.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the ATPase alpha/beta chains family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000541">
        <property type="protein sequence ID" value="OBZ84208.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N5E6"/>
    <dbReference type="FunCoup" id="A0A1C7N5E6">
        <property type="interactions" value="175"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N5E6"/>
    <dbReference type="InParanoid" id="A0A1C7N5E6"/>
    <dbReference type="OrthoDB" id="1735853at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000329">
        <property type="term" value="C:fungal-type vacuole membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045121">
        <property type="term" value="C:membrane raft"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000221">
        <property type="term" value="C:vacuolar proton-transporting V-type ATPase, V1 domain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990816">
        <property type="term" value="C:vacuole-mitochondrion membrane contact site"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046961">
        <property type="term" value="F:proton-transporting ATPase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046034">
        <property type="term" value="P:ATP metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006874">
        <property type="term" value="P:intracellular calcium ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000425">
        <property type="term" value="P:pexophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902906">
        <property type="term" value="P:proteasome storage granule assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007035">
        <property type="term" value="P:vacuolar acidification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd18112">
        <property type="entry name" value="ATP-synt_V_A-type_beta_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18118">
        <property type="entry name" value="ATP-synt_V_A-type_beta_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01135">
        <property type="entry name" value="V_A-ATPase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.12240:FF:000001">
        <property type="entry name" value="V-type proton ATPase subunit B, brain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00310">
        <property type="entry name" value="ATP_synth_B_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055190">
        <property type="entry name" value="ATP-synt_VA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020003">
        <property type="entry name" value="ATPase_a/bsu_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004100">
        <property type="entry name" value="ATPase_F1/V1/A1_a/bsu_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000194">
        <property type="entry name" value="ATPase_F1/V1/A1_a/bsu_nucl-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005723">
        <property type="entry name" value="ATPase_V1-cplx_bsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022879">
        <property type="entry name" value="V-ATPase_su_B/beta"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003235">
        <property type="entry name" value="PRK04196.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01040">
        <property type="entry name" value="V-ATPase_V1_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43389">
        <property type="entry name" value="V-TYPE PROTON ATPASE SUBUNIT B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43389:SF4">
        <property type="entry name" value="V-TYPE PROTON ATPASE SUBUNIT B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00006">
        <property type="entry name" value="ATP-synt_ab"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02874">
        <property type="entry name" value="ATP-synt_ab_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22919">
        <property type="entry name" value="ATP-synt_VA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF039114">
        <property type="entry name" value="V-ATPsynth_beta/V-ATPase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00152">
        <property type="entry name" value="ATPASE_ALPHA_BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="4 5" id="KW-0406">Ion transport</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ATPase F1/V1/A1 complex alpha/beta subunit N-terminal" evidence="7">
        <location>
            <begin position="33"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="domain" description="ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding" evidence="6">
        <location>
            <begin position="156"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="domain" description="ATP synthase A/B type C-terminal" evidence="8">
        <location>
            <begin position="391"/>
            <end position="490"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU366021"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02874"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF22919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OBZ84208.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="513" mass="57219" checksum="687CEEE737F2C3E5" modified="2016-11-30" version="1">MAKTLTAQEAFELHKSAVTRDFIAKPRLDYRTVSGVNGPLVILDNVKFPKFSEIVNLTLPDGSVRAGQVLEVQGKKAVVQVFEGTSGIDAKQTHVTFTGQTQHIPVSEDMLGRVFNGSGKPIDKGPKIFAEDYLDVNGSPINPFSRIYPEEMIQTGISAIDTMNSIARGQKIPIFSAAGLPHNEIAAQICRQAGLVQKLAPTKGVHDGHEENFSIVFGAMGVNMETARFFKQDFEENGSMERVTLFLNLANDPTIERIITPRLALTTAEYYAYQLEKHVLVILTDMSSYADALREVSAAREEVPGRRGYPGYMYTDLSTIYERAGRVEGRNGSITQIPILTMPNDDITHPIPDLTGYITEGQIFVDRQLYNRQIYPPINVLPSLSRLMKSAIGEGMTRKDHGDVSNQLYAKYAIGRDAAAMKAVVGEEALNQEDKLSLEFLEKFEKTYIAQGAYESRTIYESLDLAWSLLRIFPKELLNRIPQKVLAEYYQRERSSKRSKGVFDTNDEENAAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N5P6</accession>
    <name>A0A1C7N5P6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Protein disulfide-isomerase like 2-2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">PDIL2-2</name>
        <name evidence="9" type="ORF">A0J61_07992</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Probable disulfide isomerase, which participates in the folding of proteins containing disulfide bonds. May act as a dithiol oxidase. Acts as a regulator of endoplasmic reticulum-mitochondria contact sites via its ability to regulate redox signals.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000578">
        <property type="protein sequence ID" value="OBZ83956.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N5P6"/>
    <dbReference type="STRING" id="101091.A0A1C7N5P6"/>
    <dbReference type="InParanoid" id="A0A1C7N5P6"/>
    <dbReference type="OrthoDB" id="427280at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016853">
        <property type="term" value="F:isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02961">
        <property type="entry name" value="PDI_a_family"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="CDD" id="cd02981">
        <property type="entry name" value="PDI_b_family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052250">
        <property type="entry name" value="PDI_TMX3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017937">
        <property type="entry name" value="Thioredoxin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46426">
        <property type="entry name" value="PROTEIN DISULFIDE-ISOMERASE TMX3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46426:SF1">
        <property type="entry name" value="PROTEIN DISULFIDE-ISOMERASE TMX3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00085">
        <property type="entry name" value="Thioredoxin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13848">
        <property type="entry name" value="Thioredoxin_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00194">
        <property type="entry name" value="THIOREDOXIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="9" id="KW-0413">Isomerase</keyword>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008889498" evidence="7">
        <location>
            <begin position="19"/>
            <end position="530"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="478"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="domain" description="Thioredoxin" evidence="8">
        <location>
            <begin position="111"/>
            <end position="250"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00045246"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OBZ83956.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="530" mass="59993" checksum="C330EF998AC5B0F1" modified="2016-11-30" version="1">MKLSTIAISLIACISAEALQINEIDPKAVDAKQDGTLVVEYYLPDCTSCTDFEPIWTQLVEKYQGQASFGRLNCNTHKAYCQGKGIVKLPTIQSNINGGDWKEFTGTLTYPNVDRFIQENYISRNLEGDSIEVKRSAQLKAMIESKEPWFVKFYAPWCGHCKKLEPVWADMAKQLKGKVNVAEVNCEDSKAICQEYRVTGLPTLAYYVHGASLKYNGARDLDKLVQYALKMSGSPVHNIETDTELDKLLKETDVNLVYVTNEKEKGNLHILERAAPQFMETIPFYTTSDPKTASRFGLKTSSLPATVIVKDNGHLVYEGDMDAIVDWIHQERHPLLTRIMPHNANSILRGPDLVVLGITQSDDIQYEDKLRALARKFKEEEKKPEGVVFSQLDGRKYGNYINRVYGIQSNKLPALIILDPMNDMYYSRFQNQALFNLDKPEAILKSLKHLDKLPGISTAPSKTASVLERIVIFFGDHYIVMSTILFGFAGLLFWLVTSEGPEIKREQIREIGQQEVEERKEKEAKGEKSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N650</accession>
    <name>A0A1C7N650_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">Calcium-channel protein CCH1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="21" type="primary">cch1_1</name>
        <name evidence="21" type="ORF">A0J61_07433</name>
    </gene>
    <organism evidence="21 22">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="21 22" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="21 22">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="17">Membrane</location>
            <topology evidence="17">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="14 17">Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="21">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000501">
        <property type="protein sequence ID" value="OBZ84517.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N650"/>
    <dbReference type="InParanoid" id="A0A1C7N650"/>
    <dbReference type="OrthoDB" id="416585at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005891">
        <property type="term" value="C:voltage-gated calcium channel complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008331">
        <property type="term" value="F:high voltage-gated calcium channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098703">
        <property type="term" value="P:calcium ion import across plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.70:FF:000093">
        <property type="entry name" value="Calcium channel subunit Cch1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.70">
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.350">
        <property type="entry name" value="Voltage-gated potassium channels. Chain C"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005821">
        <property type="entry name" value="Ion_trans_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050599">
        <property type="entry name" value="VDCC_alpha-1_subunit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002077">
        <property type="entry name" value="VDCCAlpha1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027359">
        <property type="entry name" value="Volt_channel_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45628">
        <property type="entry name" value="VOLTAGE-DEPENDENT CALCIUM CHANNEL TYPE A SUBUNIT ALPHA-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45628:SF7">
        <property type="entry name" value="VOLTAGE-DEPENDENT CALCIUM CHANNEL TYPE A SUBUNIT ALPHA-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00520">
        <property type="entry name" value="Ion_trans"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00167">
        <property type="entry name" value="CACHANNEL"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81324">
        <property type="entry name" value="Voltage-gated potassium channels"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 16 17" id="KW-0106">Calcium</keyword>
    <keyword evidence="5 17" id="KW-0107">Calcium channel</keyword>
    <keyword evidence="4 17" id="KW-0109">Calcium transport</keyword>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="12" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="13" id="KW-0407">Ion channel</keyword>
    <keyword evidence="10" id="KW-0406">Ion transport</keyword>
    <keyword evidence="11 19" id="KW-0472">Membrane</keyword>
    <keyword evidence="16" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="22" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 19" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 19" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <keyword evidence="8 17" id="KW-0851">Voltage-gated channel</keyword>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="199"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="231"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="355"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="422"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="553"/>
            <end position="575"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="625"/>
            <end position="643"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="711"/>
            <end position="732"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="744"/>
            <end position="767"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="817"/>
            <end position="840"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="1023"/>
            <end position="1042"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="1062"/>
            <end position="1086"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="1093"/>
            <end position="1111"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="1131"/>
            <end position="1149"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="1156"/>
            <end position="1179"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="1265"/>
            <end position="1287"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="1344"/>
            <end position="1364"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="1376"/>
            <end position="1396"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="1408"/>
            <end position="1427"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="1473"/>
            <end position="1491"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="1553"/>
            <end position="1579"/>
        </location>
    </feature>
    <feature type="domain" description="Ion transport" evidence="20">
        <location>
            <begin position="355"/>
            <end position="584"/>
        </location>
    </feature>
    <feature type="domain" description="Ion transport" evidence="20">
        <location>
            <begin position="620"/>
            <end position="851"/>
        </location>
    </feature>
    <feature type="domain" description="Ion transport" evidence="20">
        <location>
            <begin position="1028"/>
            <end position="1293"/>
        </location>
    </feature>
    <feature type="domain" description="Ion transport" evidence="20">
        <location>
            <begin position="1344"/>
            <end position="1583"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="18">
        <location>
            <begin position="15"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="18">
        <location>
            <begin position="1820"/>
            <end position="1854"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="18">
        <location>
            <begin position="1838"/>
            <end position="1853"/>
        </location>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="1234"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022568"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022673"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022882"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00061395"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00067459"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PIRSR" id="PIRSR602077-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="RuleBase" id="RU003808"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="Pfam" id="PF00520"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="EMBL" id="OBZ84517.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="1915" mass="219954" checksum="28E9E3B6094AE507" modified="2016-11-30" version="1">MSHLFQDYRFGSEIDSSDNRSNASLIAPNSDRSSVHNNAYYPPLTKAALENRNKLNVTTLKRPTSLVNSTHFSYESSQAGGSNRNSISDHRLPSTSIPLTAHTNQSWLDCLFAMSERVIDSRNSEPKDTRISVDLASSCMNASIIQHMIRFFRHSRELHPEEDGDVKHEVIQLEGWSLFLLSPTSSIRINLWRWIGSRWFEITMLVLLISQWILLSIEPKLIGSLKMTPTHILYCLIQSVFTMEMMAKIVVYGFCFNTRPSFRWISDYVYRQRGYEPVNPPELDEDMDQNSIPPIFHYRDRLTSFAADNAIRPSSTANGSITSDSLEDSVSALTASSSSTISAQTHVLQVHHHPYCASLVNMVDMMAIIAYWLQLILSATDTSWSPLSVFACCRLFRFLALTEGTQTLMISIYGSLDMLKNVMGFFVFFWVLFSLAALGLFPNAFTRQCAIVNETISWVEPRLACAGYWLDGERVGPLDWPSQTQLIYTGTDGYYCQLGQVCIQDTQNQPMHGHLSFQHMGYAMLNMFTIISTENWTDLLYIAQDSTSTWGTALFFASCIYVMTFILVPMFIAVITSSFSQGKQASPNGTQEKLQDWVDQDASSLYRSEWQVLCYRISHHPYFQYAMNGLTLLSVIPMAWYPMDMVAGEWTIKGLLQRLMDSLFCIEIVIRAMGYLTLKQFWFDGRRNQFDAVIALATVLDSLPLFNRFHLILIIFPILRFYRILYLFPGVLQLTTDVIGDGKGVQNLVCFTFLVLFILASISVQLFGGDFEFAKDEPAMLFDTFYQAFLSLFQIMTGENWVDILYDAMHSQEYRSVTFAAVFISLMYFIVHYLVLNLFVAVIMQNFDLEDEEIKRIQIKKYIERKQLKPAYFHWDQFTRLLVPVSLYLEKKLLKITQLPQHLVARVNRHQFKQFYDVAADYGSLDAPSWYAEDFSTGRSSPPASIISSGSSVISHRRTSVASVQSTHQPFHEPMRYVDDYDEQITKENNAVIMENLQLLGSLMLFRRDSQIYHLCVQWTKSTLYKVIIIMLICLGSGLALWADEYHRVHDADQIAHVVEPIHRVLIVLYFGNVVVHGIANGLIILPDAYLRKLWNVLDVCNLIIQAILMVFGKDVASYLRVLRTLRVLRIMYHIQTMRHIFLDLLYGLPKLVDVVLLNLLVFLSFAVYGCALFSGQFVSCNEDGLVKQACTFEFASDDTMGILVPRVWENPYDYSFDTFGASFLHLFECASGEGWIRSLFTAMSVQRDQPLEFGWSMRAITHSMYYVVFMFIASLCSIQLFIGVFLEIFKQRNGISQLTSKQRQFQDLQRQLALLKPSRRVFRPQHPIRAFFYDLVINKRGRFARWMAHVIMINIVVFATEHLYQPFWLTQLQNILNGVCIGFYVFEIIAKILGLGFSKWKSIIWNVYDFVLVCLVLIAFVLKFYVGRNNLIEFTLTSCSKLFSVGIAFRLAQRNESLDTLFKSIRRAIPSIASVSCVFSLVMLCFAVFFQEIFGLTRYGPYGNDHANFRSLFNSILTLFRITTGEDWDALMHDFFISPFSCVNKNDCGSPFYAIVLFSTFYIMCTYIFVNLFTMIVIDNFSFTFDKRNRFTLITRSDLRNFKIAWSQEDPYATGYISVDQVPRFLSQLEGVLSIRVYDEKHSIANLMAASKQFDINPTHLTSISGSDQNKNKEQLFNFHQLNQQLTTMDSKTIRLRKRRYAEVYKEVVNTATRKGVEFRTMLKILAMQLIDASSSLRFDALIHHSRMKQQIEQQLAFENAHGLINMMVARRRFLKWRQGKPHVSSEPHTRNSIAIVGQWLQPSVPDPQRQENVPKIIIDSADPKSPSDESIASPFYSGSRSPSVYDQSPGNDTLRKINSMPSLLSPSSPTHHDIAYHCYVEDDKVQHMDIKTANDLMQHLNESVWSDMLVESG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N6G7</accession>
    <name>A0A1C7N6G7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Peroxisomal ATPase PEX1</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Peroxin-1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">A0J61_07208</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="7">
            <dbReference type="Rhea" id="RHEA:13066"/>
        </physiologicalReaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the AAA ATPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000475">
        <property type="protein sequence ID" value="OBZ84743.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N6G7"/>
    <dbReference type="FunCoup" id="A0A1C7N6G7">
        <property type="interactions" value="872"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N6G7"/>
    <dbReference type="InParanoid" id="A0A1C7N6G7"/>
    <dbReference type="OrthoDB" id="27435at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030687">
        <property type="term" value="C:preribosome, large subunit precursor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990275">
        <property type="term" value="F:preribosome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007031">
        <property type="term" value="P:peroxisome organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042273">
        <property type="term" value="P:ribosomal large subunit biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000055">
        <property type="term" value="P:ribosomal large subunit export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd19518">
        <property type="entry name" value="RecA-like_NVL_r1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd19530">
        <property type="entry name" value="RecA-like_NVL_r2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000149">
        <property type="entry name" value="Nuclear valosin-containing protein-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000365">
        <property type="entry name" value="Ribosome biogenesis ATPase RIX7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050168">
        <property type="entry name" value="AAA_ATPase_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041569">
        <property type="entry name" value="AAA_lid_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003960">
        <property type="entry name" value="ATPase_AAA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23077">
        <property type="entry name" value="AAA-FAMILY ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23077:SF171">
        <property type="entry name" value="NUCLEAR VALOSIN-CONTAINING PROTEIN-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17862">
        <property type="entry name" value="AAA_lid_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00674">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="2" id="KW-0962">Peroxisome biogenesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="9">
        <location>
            <begin position="245"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="domain" description="AAA+ ATPase" evidence="9">
        <location>
            <begin position="597"/>
            <end position="733"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="77"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="128"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="447"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="84"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="132"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="185"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="447"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="470"/>
            <end position="483"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006914"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00032509"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00034532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00048778"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OBZ84743.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="840" mass="92204" checksum="CD89F1C63B72E254" modified="2016-11-30" version="1">MRGGSRGSRPGGAAGGGNYYRMSRLNENKIANCLDLYKAEGLTDMSPMVLIDYCLKVDSSLRRQKRRLLEIALESVLSEKEQETTPANESATEQASVDEDAAAEYAVPAQEDNAMNKSVTSLWNIHTKPASGVSTPVKSEASTPVNEDIPQPMNTTTSNEEAPVEPAGTTAVNESTKSKKRPQKTTKDVATKRPKTSSESREAPFIPTAKLSDLGGIDHCIEEIMELIAMPLAHPEVYLHTGVQPPRGVLLHGPPGCGKTRLAHAIAGELSIPFFNISAPSIVSGMSGESEKKIREVFEEARENAPCLLFIDEIDAITPKRETAQREMERRIVAQLLTCMDDLSWEKCNNKPVMIIGATNRPDSLDAALRRAGRFDREISMGVPDEKAREKILRVLASKLRLEGDFDFAELAKATPGYVGADLQALITTAGVIAVKRIFKHLQAATAGSRSTSDDIQPNTDLESNSNEKQDEEEEDNSMDIDDTTIPTNNEPIQITSVEEFEAQTPLEQIRNISEFIKSHREPLTEAQLESLAITQEDFKHSLKKVQPSSKREGFATVPDVSWDDIGALQFVRDELRMAVVEPINHPEFFERVGITNPAGVLLWGPPGCGKTLLAKAVANESNTNFISVKGPELLNKYVGESERGVRQVFARARASAPCVIFFDELDALCSRREDQQTDASARVVNTLLTELDGVENRSQVYVIAATNRPDMIDPAMLRPGRLDKLLYVELPTPSERLDILIKLSKKTPLAEDVSLVDIANDARCEGLSGADLASLVRESAVSALRSNFYSSGVMNTAALTTAEEIFVTKKDFDVAFTKVSPSVLPQDKLHFDRLRKKYG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N6V9</accession>
    <name>A0A1C7N6V9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="11">SWI/SNF complex subunit SMARCC2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">SMARCC2_0</name>
        <name evidence="11" type="ORF">A0J61_07085</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the SMARCC family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000461">
        <property type="protein sequence ID" value="OBZ84860.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N6V9"/>
    <dbReference type="InParanoid" id="A0A1C7N6V9"/>
    <dbReference type="OrthoDB" id="118550at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016514">
        <property type="term" value="C:SWI/SNF complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048858">
        <property type="term" value="P:cell projection morphogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd00167">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.10:FF:000020">
        <property type="entry name" value="SWI/SNF complex subunit SMARCC2 isoform c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.60:FF:000014">
        <property type="entry name" value="SWI/SNF complex subunit SMARCC2 isoform C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049898">
        <property type="entry name" value="MARR_BRCT_CHROMO"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001005">
        <property type="entry name" value="SANT/Myb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017884">
        <property type="entry name" value="SANT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007526">
        <property type="entry name" value="SWIRM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15381:SF1">
        <property type="entry name" value="CHONDROITIN SULFATE PROTEOGLYCAN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15381">
        <property type="entry name" value="CHONDROITIN SULFATE PROTEOGLYCAN 5 -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00249">
        <property type="entry name" value="Myb_DNA-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04433">
        <property type="entry name" value="SWIRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00717">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52032">
        <property type="entry name" value="MARR_BRCT_CHROMO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50090">
        <property type="entry name" value="MYB_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51293">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50934">
        <property type="entry name" value="SWIRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Chromo" evidence="10">
        <location>
            <begin position="1"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="domain" description="SWIRM" evidence="8">
        <location>
            <begin position="313"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="domain" description="Myb-like" evidence="7">
        <location>
            <begin position="536"/>
            <end position="586"/>
        </location>
    </feature>
    <feature type="domain" description="SANT" evidence="9">
        <location>
            <begin position="539"/>
            <end position="590"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="259"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="427"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="502"/>
            <end position="549"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="784"/>
            <end position="823"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="678"/>
            <end position="709"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="437"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="513"/>
            <end position="527"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="528"/>
            <end position="545"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="784"/>
            <end position="808"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00049655"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50934"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51293"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS52032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="OBZ84860.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="823" mass="95439" checksum="ECC64CDC715263CC" modified="2016-11-30" version="1">MNRAEEPSIDLTYYEQPSTISYFDAILNDLKADLESLGCDTAFTAPELAYFTGRFYRYQTYAPVTRIPTRFFDVETLHKPSPLYSILLSACSFQSDKDLNDWEFDRREEESLYIELMNTVKDQLAQDGFCMAPLIAFDEQVGLHQIHEWTQLAQALGGQISSVTKATHIIYNNIDPVQSAYYIEKTQHGRSWVHFVGLPESHNRWVEQLPSEPQVPKPTIIAPYHLRATWLLDSYRYREWMVPADYDYPDKRNQLKRSVVDPSVDLPSKKSKTPEEEQFSADMKEPLLPINLAAIPLPEDNKQRYYSIQAQDIIIPSYAAWFDITCVHRIEARSLPEFFNSQNESKTPSVYKEYRDFMINTYRMNPVEYLTITACRRNLTGDVCAILRVHSFLEQWGLINYQVDPEAKPSSLSASFDSQFKIVMDRPSADDDEEEEIEKKEETVKEEPGITHYDFGKTKEPQACSSCHTVCTEQQYCSTRVPDFYLCSTCYREGNYPSKHKSGHFVLEQLPKSTREKKDKEEEKEKEGNEEEDEEQTEEVQEEWTEQEKERLKEGVKLFEDSWEKIADHVGTRTHDECVLEYLQLPTKDPFEDAELEELGLLQYDIEKPRENPVMTAVAFLGSSVKPRVALATINHLDSMPEGKEKEDESEAEDRLLELTNGLFQHKLKYYQQRTAHYEALEGIVEDQKRLLEKERRQLEHDQANLKRKLFHLRLKMASQSSSATAIANSITPAXIQQQQLIGTSPSMLLSNTPNEQGPPAALLQSQTSMPHPIHQSPQMLQQMHHQQQYHLQMQMQLQQQQRLQAQPQQPPHPPNFNNMMPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N7A5</accession>
    <name>A0A1C7N7A5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">thymidylate synthase</fullName>
            <ecNumber evidence="2">2.1.1.45</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">CDC21</name>
        <name evidence="9" type="ORF">A0J61_06909</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>dUMP + (6R)-5,10-methylene-5,6,7,8-tetrahydrofolate = 7,8-dihydrofolate + dTMP</text>
            <dbReference type="Rhea" id="RHEA:12104"/>
            <dbReference type="ChEBI" id="CHEBI:15636"/>
            <dbReference type="ChEBI" id="CHEBI:57451"/>
            <dbReference type="ChEBI" id="CHEBI:63528"/>
            <dbReference type="ChEBI" id="CHEBI:246422"/>
            <dbReference type="EC" id="2.1.1.45"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Pyrimidine metabolism; dTTP biosynthesis.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.45" evidence="2"/>
    <dbReference type="EMBL" id="LUGH01000440">
        <property type="protein sequence ID" value="OBZ85035.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N7A5"/>
    <dbReference type="STRING" id="101091.A0A1C7N7A5"/>
    <dbReference type="InParanoid" id="A0A1C7N7A5"/>
    <dbReference type="OrthoDB" id="766at2759"/>
    <dbReference type="UniPathway" id="UPA00575"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004799">
        <property type="term" value="F:thymidylate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006231">
        <property type="term" value="P:dTMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006235">
        <property type="term" value="P:dTTP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00351">
        <property type="entry name" value="TS_Pyrimidine_HMase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.572.10:FF:000002">
        <property type="entry name" value="Possible thymidylate synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.572.10">
        <property type="entry name" value="Thymidylate synthase/dCMP hydroxymethylase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00008">
        <property type="entry name" value="Thymidy_synth_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045097">
        <property type="entry name" value="Thymidate_synth/dCMP_Mease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023451">
        <property type="entry name" value="Thymidate_synth/dCMP_Mease_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036926">
        <property type="entry name" value="Thymidate_synth/dCMP_Mease_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000398">
        <property type="entry name" value="Thymidylate_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020940">
        <property type="entry name" value="Thymidylate_synthase_AS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF002497">
        <property type="entry name" value="PRK01827.1-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR03284">
        <property type="entry name" value="thym_sym"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11548:SF2">
        <property type="entry name" value="THYMIDYLATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11548">
        <property type="entry name" value="THYMIDYLATE SYNTHASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00303">
        <property type="entry name" value="Thymidylat_synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00108">
        <property type="entry name" value="THYMDSNTHASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55831">
        <property type="entry name" value="Thymidylate synthase/dCMP hydroxymethylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00091">
        <property type="entry name" value="THYMIDYLATE_SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="5" id="KW-0545">Nucleotide biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Thymidylate synthase/dCMP hydroxymethylase" evidence="8">
        <location>
            <begin position="9"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="active site" evidence="7">
        <location>
            <position position="174"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00047344"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OBZ85035.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="298" mass="34332" checksum="3B2AB53930EEA97A" modified="2016-11-30" version="1">MTVPHEEYQYLDLIKRIMSEGEHRADRTGTGTLAIFAPPQMRFSLKNDIFPLLTTKRVFYRGVLEELLWFIRGDTNSKHLSDRNVKIWDGNGSREYLDRIGLTDRREGDLGPVYGFQWRHFGAKYVDCDTDYTGQGVDQLQQVIDTIKNNPTDRRIILSAWNPADIPIMALPPCHSFCQFYVSTPINGEPAKLSCVLYQRSCDMGLGVPFNIASYALLTRMIAHVTDLEPGEFIHTMGDTHVYVDHLEGLKQQIQREPRPFPTLKINRKVTNIDDFKFEDFVLENYNPHGKIDMKMSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-06-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N7H9</accession>
    <name>A0A1C7N7H9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_06853</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000434">
        <property type="protein sequence ID" value="OBZ85095.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N7H9"/>
    <dbReference type="InParanoid" id="A0A1C7N7H9"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ85095.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="184" mass="21009" checksum="52BFFDB4AE8C1EC1" modified="2016-11-30" version="1">MLTFIVLLSNCKGNVAFEESKEIVYNEYYSPETCKEYGGMAECYGDLLYLRSRVNYLDDTIRVFRKRSSLSTDEISLVTSTVENLQYHAQSTHAKCCDLALGYQKFIDDDSSDEEGVSQNDKDRLKPITKELLAMNRQLITRIGPGSRFASKCNEWQYLVDGLTALQDDLGAISYQCLKKRIIH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N7L8</accession>
    <name>A0A1C7N7L8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Autophagy protein 5</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">ATG5</name>
        <name evidence="9" type="ORF">A0J61_06913</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Involved in cytoplasm to vacuole transport (Cvt) and autophagic vesicle formation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Conjugated with ATG12.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Preautophagosomal structure membrane</location>
            <topology evidence="5">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the ATG5 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000440">
        <property type="protein sequence ID" value="OBZ85037.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N7L8"/>
    <dbReference type="FunCoup" id="A0A1C7N7L8">
        <property type="interactions" value="248"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N7L8"/>
    <dbReference type="InParanoid" id="A0A1C7N7L8"/>
    <dbReference type="OrthoDB" id="272162at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034274">
        <property type="term" value="C:Atg12-Atg5-Atg16 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005776">
        <property type="term" value="C:autophagosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044233">
        <property type="term" value="C:mitochondria-associated endoplasmic reticulum membrane contact site"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061908">
        <property type="term" value="C:phagophore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034045">
        <property type="term" value="C:phagophore assembly site membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019776">
        <property type="term" value="F:Atg8-family ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000422">
        <property type="term" value="P:autophagy of mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006995">
        <property type="term" value="P:cellular response to nitrogen starvation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034727">
        <property type="term" value="P:piecemeal microautophagy of the nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.246.190">
        <property type="entry name" value="Autophagy protein Apg5, helix rich domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007239">
        <property type="entry name" value="Atg5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048940">
        <property type="entry name" value="ATG5_HBR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042526">
        <property type="entry name" value="Atg5_HR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048939">
        <property type="entry name" value="ATG5_UblA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042527">
        <property type="entry name" value="Atg5_UblA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048318">
        <property type="entry name" value="ATG5_UblB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13040">
        <property type="entry name" value="AUTOPHAGY PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13040:SF2">
        <property type="entry name" value="AUTOPHAGY PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20637">
        <property type="entry name" value="ATG5_HBR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20638">
        <property type="entry name" value="ATG5_UblA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04106">
        <property type="entry name" value="ATG5_UblB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0072">Autophagy</keyword>
    <keyword evidence="2 5" id="KW-1017">Isopeptide bond</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <keyword evidence="3 5" id="KW-0832">Ubl conjugation</keyword>
    <feature type="domain" description="Autophagy protein ATG5 UblA" evidence="8">
        <location>
            <begin position="12"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="domain" description="Autophagy protein ATG5 alpha-helical bundle region" evidence="7">
        <location>
            <begin position="124"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="domain" description="Autophagy protein ATG5 UblB" evidence="6">
        <location>
            <begin position="188"/>
            <end position="268"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022499"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022843"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU361202"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF04106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF20637"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF20638"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OBZ85037.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="272" mass="31549" checksum="15FF365070A3A84B" modified="2016-11-30" version="1">MSVYDYAFAKHVWNGKLPVKITLDPTGVDLGNGKEWDPIYLEVPRCSYLPLVTRHIQKIIKDFDMQIPDESFQSVWYEADHLPLKWHYPIGLLFDLHANTLPWTLTMHFTDLPTESILLKPTPETMQDMFMSMVKEADFLRFGTTKKVMNLSKRDSTQLWQSLASDQYDDFRAVNKQLTEYSNNLRDVPIKVYLPDQCPVIQGLVPFHQDSEIPILSQVVTKLIPALDEQTLASVLIMTHGIELPLDMPIHWAYENLCYADNFLHLVIKQKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N7M3</accession>
    <name>A0A1C7N7M3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_06806</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000428">
        <property type="protein sequence ID" value="OBZ85145.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N7M3"/>
    <dbReference type="InParanoid" id="A0A1C7N7M3"/>
    <dbReference type="OrthoDB" id="2289675at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="96"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="98"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="145"/>
            <end position="155"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ85145.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="169" mass="18990" checksum="CCA93F0EC260844B" modified="2016-11-30" version="1">MDFTTDTESNPIRFSQTSLQTEDSFDSTSLATPLDASPLPPPSNTFSLINIVNNDPLPDPKEYNAIASVYTRRRAQTAPLPILVSTEQSILQQYPVISNSSNSTDDTSTATANGKQSRLWPKLKRMMMPKTSDRTTLDPKPNVNHNEKTNQDQTKRWLSRNRVRVGPQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N7Q3</accession>
    <name>A0A1C7N7Q3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Transmembrane protein 62</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">Tmem62_1</name>
        <name evidence="5" type="ORF">A0J61_06776</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000425">
        <property type="protein sequence ID" value="OBZ85175.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N7Q3"/>
    <dbReference type="STRING" id="101091.A0A1C7N7Q3"/>
    <dbReference type="InParanoid" id="A0A1C7N7Q3"/>
    <dbReference type="OrthoDB" id="45365at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056229">
        <property type="entry name" value="Ig_TMM62"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056230">
        <property type="entry name" value="TMEM62_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14795">
        <property type="entry name" value="HELICASE RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14795:SF0">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 62"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24384">
        <property type="entry name" value="Ig_TMM62"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24394">
        <property type="entry name" value="TMEM62_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="Metallo-dependent phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="488"/>
            <end position="507"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="564"/>
            <end position="582"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="701"/>
            <end position="719"/>
        </location>
    </feature>
    <feature type="domain" description="Calcineurin-like phosphoesterase" evidence="2">
        <location>
            <begin position="69"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="domain" description="TMEM62 Ig-like" evidence="3">
        <location>
            <begin position="360"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="domain" description="TMEM62 C-terminal" evidence="4">
        <location>
            <begin position="492"/>
            <end position="643"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF24384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF24394"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OBZ85175.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="821" mass="94966" checksum="2BC6884CA68660E2" modified="2016-11-30" version="1">MNRKGVFYILVTVICCLRAFQLFLSATKELRSEVQWFPLSSKPKPSAFDHAQKNDSTILGTESDNVFYFVHATDLHLSRFRPKGHTFHFLHFIQSILPVVRPEFVVVTGDLTDAKDKKRVTSQQYHDEWQIYQQAISEKVTVDWYDMRGNHDCFDLPSWQSRVNYYRTHGQKAERVEKGQGIYAWQFYQPSSAYQFVAIDACPKKGPSRPLNFFGYLTSKTMDQLEKALVSTSFNHTFVFSHYPTTTMVFGTSKNGRTFRDLASHYSVYFCGHLHKLIAGLGDVLKSYDPVTRSLELELGDLKEHGLYRIVAVDHDLISFVDIQLPLDQIPKVGPVNELGLVQPITKDMKIIWPEQVQPAPSILVTNPKDARFSIPSKEPLHRIRHSSHIRFLVFSQGDYSKLKVELFIDDKPHLFAASFVGDTKTPLWTAPWNATFYEDKRAHQLRVQVTQPNGQTGVSKTIFRVDSQRIKIGGGTGEFIIKSKMATLLQCITLLTMSSILLFLILPQCIGIHDVQYTAHIQRLLLRIHWIDQQKTTSVYLRLQKQILAWSIRYMQLPKDQPVVWHTTFVYILCLLTMPWFRANFIPSADTQQERYGIFYMWGMVFQDEWIPIADTWMLAAEQVVLDVFVFFMLVTWRSTDSVDFTCQGQISKQIGRQLNEKPWFKGLEAVYWLWRSSELVALASFYGGIWPTLVQNINVYWMLFSGFTLAWGKNGMFSRKRKQHRYLKFVQGCVTCQQHYQYQRKEKQATEEITSNSAIQESVLQYDSSNANLNASLTQEEEQQLKTKKVAGIIRSDSSSSTSFDDLPLIKNRRKPLKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N8K5</accession>
    <name>A0A1C7N8K5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">GTP-binding protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">GTPBP1</name>
        <name evidence="5" type="ORF">A0J61_06524</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000397">
        <property type="protein sequence ID" value="OBZ85423.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N8K5"/>
    <dbReference type="STRING" id="101091.A0A1C7N8K5"/>
    <dbReference type="InParanoid" id="A0A1C7N8K5"/>
    <dbReference type="OrthoDB" id="248233at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd04165">
        <property type="entry name" value="GTPBP1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03694">
        <property type="entry name" value="GTPBP_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03708">
        <property type="entry name" value="GTPBP_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.30.10:FF:000084">
        <property type="entry name" value="GTP-binding elongation factor Tu family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.30.10:FF:000014">
        <property type="entry name" value="Probable GTP-binding protein 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000091">
        <property type="entry name" value="Probable GTP-binding protein 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.10">
        <property type="entry name" value="Translation factors"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050055">
        <property type="entry name" value="EF-Tu_GTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004161">
        <property type="entry name" value="EFTu-like_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035531">
        <property type="entry name" value="GTPBP1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000795">
        <property type="entry name" value="T_Tr_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009001">
        <property type="entry name" value="Transl_elong_EF1A/Init_IF2_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43721">
        <property type="entry name" value="ELONGATION FACTOR TU-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43721:SF9">
        <property type="entry name" value="GTP-BINDING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00009">
        <property type="entry name" value="GTP_EFTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03144">
        <property type="entry name" value="GTP_EFTU_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50465">
        <property type="entry name" value="EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="Translation proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51722">
        <property type="entry name" value="G_TR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tr-type G" evidence="4">
        <location>
            <begin position="166"/>
            <end position="397"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OBZ85423.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="590" mass="65292" checksum="31C7F80E052D11DB" modified="2016-11-30" version="1">MVEGNKTGNHLDEASLLASALSNTSIHDDKQHEALLDNMLDNLMDSGTEERGYHHNTLKQVLLEPTEQDLDYLTDLLSTRIEQGRGETLFEIGIDEDGSSMKLTPTDYSKCIETITKVTDKLEADFANIDDLDELDPTKEKSIEKTQEDIVAHLMIRKRPKSVEDLLEIRVAVVGNVDAGKSTMLGVLTKGVLDDGRGKARVNLFRHKHEIESGRTSSVGGEILGFDSKSKPVMIHTSHSVKKASSWEDIAAKAAKVLSFVDLAGHEKYLKTTVFGMTGSAPEFAMLMVGANAGMIGMSKEHLGLALSLNIPVLVVITKIDRCPQHVLEKTTKELTSILKSKSCRKIPLFVDNNHDVVMTAQNFVSERLCPIFQVSNVTGQGLDLIRNFLNVLPSLTRYETDQPFHYEINETYSVPFVGTVVSGVMKSGVIHIGDKVLLGPDHAGQFVTTTIKGIHRKRVSVPAARAGQSVTFALKNVRRNTIRKGQVLLAYDKDKPTFVPPTSKRFEAEVLVLYHSTTIKNKYQAMVHCGAVRQTARILTTDKSVLRTGDRAKVEFEFVKNPEYLTVGTRLIFREGRTKGVGKITRLLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N8R1</accession>
    <name>A0A1C7N8R1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcription factor 25</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">TCF25</name>
        <name evidence="2" type="ORF">A0J61_06490</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000394">
        <property type="protein sequence ID" value="OBZ85457.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N8R1"/>
    <dbReference type="FunCoup" id="A0A1C7N8R1">
        <property type="interactions" value="528"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N8R1"/>
    <dbReference type="InParanoid" id="A0A1C7N8R1"/>
    <dbReference type="OrthoDB" id="205993at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990112">
        <property type="term" value="C:RQC complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006994">
        <property type="entry name" value="TCF25/Rqc1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22684">
        <property type="entry name" value="NULP1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22684:SF0">
        <property type="entry name" value="RIBOSOME QUALITY CONTROL COMPLEX SUBUNIT TCF25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04910">
        <property type="entry name" value="Tcf25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="569"/>
            <end position="602"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="47"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="66"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="575"/>
            <end position="586"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ85457.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="633" mass="73468" checksum="8CB8D2B14BF1416D" modified="2016-11-30" version="1">MSSRALRRLQKEQLEATVPSDEESEPESKPVKKFNPFDLLNDNPSDHDEEEQEQEQEEPIYQPVQKSKKKNKKKKKKQAKQEEDQDDEDFSMKDLDNVLKEFKLNSQQETESHPRICHELLSVNYRYLDAEAEMKRLFGSHVVNSERQQTQSRVLKKSKFTTPKSEWPPYKRHGLSMELIETKDGVGHYAFRHAETYQDVQIEFLNAVAMHHPEALLFLTRKHPYHVDSLLQLSEIAKYSGDWTTAGDFIERALYACERALHPQFSLGNSRLSYQRSENRSFFLAIFRHIQFLTRRGCWKTAFEFNKLLFSLDPESDPLGSLLSLDYHALSSRDYDYLIRLASDWKTAGVQYPVDLMNLPNMAFSSAYAQFKLSVKKKGSLTEADRSLQLAIQKYPSVYYRLMEKLGEPSTAQLDPNSDYMEIVQQLYVERTHGLWKEPEVLDWLKQNASAVKSSDAQHALLCQQTIPVSVYRHLVLIDIQSLLHYLPTDGQSIQMYDPFPPEDSVTQYDINDRVRSNTPRIDENGMMGILRNLLGHAGDNMEPEQQQRIHQLMTELEQLREQRANLAPGAFPQDSDEEDEGEEDDLHPLEDATLNHQGLSTEEMMDIMQAVGDEDLEVQRVLTEAFERNQRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N8X2</accession>
    <name>A0A1C7N8X2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_06397</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000384">
        <property type="protein sequence ID" value="OBZ85550.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N8X2"/>
    <dbReference type="STRING" id="101091.A0A1C7N8X2"/>
    <dbReference type="InParanoid" id="A0A1C7N8X2"/>
    <dbReference type="OrthoDB" id="5396786at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055105">
        <property type="term" value="F:ubiquitin-protein transferase inhibitor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019516">
        <property type="entry name" value="Glomulin/ALF4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013877">
        <property type="entry name" value="YAP-bd/ALF4/Glomulin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15430">
        <property type="entry name" value="GLOMULIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15430:SF1">
        <property type="entry name" value="GLOMULIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08568">
        <property type="entry name" value="Kinetochor_Ybp2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ85550.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="631" mass="72842" checksum="FA436C928CF56FC8" modified="2016-11-30" version="1">MADSYFYSNLRYLINNTDIELEVVTESNEVVTESNENDQSHTELTQESSEQELLLIQLKQSYQSLKKETNQSTAGCDLMSNLFPFLNHANRQIQAAAYHTLLLIADQMDCDDLSEAMMDQLICLSWEDPIEEATRLSAAYLELFGKGLEKMTRARDWMLFIPFLSNYYIKSLHHIESLLLDKATLDSSPPNASDQAVLLFAHNFLDFLEFVNDKTVSKELTEFPFDSHDIGSENGDVRRQYLVFSLLTLFYEKIIAHFNLELSKTYFNTYHASYNVTNTLPDHPSDSAHTPSEPILDIISRCRKIVTRTSLQYEKLLQLQRSLDQHKSSDLSEEDIAMINDRQMINSRLYPISLKGFAILSSLSLSEQVISRRKDVSFWPEKADNYSIAKNCIGMLLNLTLSPSKNIQETDKGVFVMLYLSDNMKSTVTMDSIDKKIKGPLGYQFEFPVSQIVQVLSSVASMCPDKSIRFCAYKLIEKFLYFCTDEARVFFLIELIEHCPFPSMNTAAINLLKDQVAYSFKHAETFSMFASPLLVGKFFPLIFHFKQDYRTSAEAFWDDFSHIMQILNFYYFLLQQDRSLNVTTVWSQDQRNWVKTNYLTPLTSLLDKLRLACDIPMQEMQLDTIIIQQII</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N936</accession>
    <name>A0A1C7N936_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Rho-GTPase-activating protein 8</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">rga8_1</name>
        <name evidence="5" type="ORF">A0J61_06308</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000375">
        <property type="protein sequence ID" value="OBZ85642.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N936"/>
    <dbReference type="FunCoup" id="A0A1C7N936">
        <property type="interactions" value="27"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N936"/>
    <dbReference type="InParanoid" id="A0A1C7N936"/>
    <dbReference type="OrthoDB" id="2155291at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000935">
        <property type="term" value="C:division septum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007010">
        <property type="term" value="P:cytoskeleton organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007264">
        <property type="term" value="P:small GTPase-mediated signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.60">
        <property type="entry name" value="Arfaptin homology (AH) domain/BAR domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.555.10">
        <property type="entry name" value="Rho GTPase activation protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027267">
        <property type="entry name" value="AH/BAR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031160">
        <property type="entry name" value="F_BAR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001060">
        <property type="entry name" value="FCH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008936">
        <property type="entry name" value="Rho_GTPase_activation_prot"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000198">
        <property type="entry name" value="RhoGAP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23065">
        <property type="entry name" value="PROLINE-SERINE-THREONINE PHOSPHATASE INTERACTING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23065:SF17">
        <property type="entry name" value="RHO-GTPASE-ACTIVATING PROTEIN RGD2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00611">
        <property type="entry name" value="FCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00620">
        <property type="entry name" value="RhoGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00055">
        <property type="entry name" value="FCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00324">
        <property type="entry name" value="RhoGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103657">
        <property type="entry name" value="BAR/IMD domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48350">
        <property type="entry name" value="GTPase activation domain, GAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51741">
        <property type="entry name" value="F_BAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50238">
        <property type="entry name" value="RHOGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-BAR" evidence="4">
        <location>
            <begin position="17"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="domain" description="Rho-GAP" evidence="3">
        <location>
            <begin position="466"/>
            <end position="665"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="152"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="744"/>
            <end position="817"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="160"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="181"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="768"/>
            <end position="781"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="782"/>
            <end position="795"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="807"/>
            <end position="817"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50238"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OBZ85642.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="817" mass="92766" checksum="FEAEE246CB01D4B8" modified="2016-11-30" version="1">MTTQHFKSVFWSQKQLEKSVPDFQAGFSVLHQKLGQSKVENEEMIGFFKERIAIEELYAQKLGDQGRQSLRSAGFGRDEGAGLLKCFSKLKETSQVIGEQHKRTAFTISEEVLMPLQDFHEEYKRVIGNSRQAMDSMLKQFDGLIKETEKAKTNYHRKCRDADKVKESTSKAIGEEGTEEEGQKKGEQKEEEEEKKKQAAPETASPLPELATSVQLGNQVMPRSELDTLIRQMRREITLRDYKVPILGTYKNTSTGEDIAIWLQQNLPQCKDSPVMSDLVGQQLIHPYNMLRLVGQRGNKFVASPSSYYQWRVSEEELASAHSDAGYSALGGLINNTTVPDDPYKRARREAERYEQTYRLSVLKLDQMRMAIEEAMFAHLKEMEQVELHRIERLKKFISAFIAALSSSIPQDKRAVEEMMIFHESLKPDQDIQFIIQQYAVAGFSPKAIMYENYYHGISQDQVFGVPLEDLGKQEHSKVPKFVSCLLSTVENQVDQVEDKEVKQKLWSTPCALDRVHSACLELNVQANSVDMELFKGYDAGLLVAVLRYFLLELPECLMTYEFYDPVDALLGGSYGDQDETLRLTSFGNLIATLPAAHFATLQVIFNHIKSFIKTTSAPSDIVDQICQTMGPVILKNRNDTFSTLNSRVPFKFCQALICNYDDIFSETTFKLHAESEKRRHAKPIVAQTEEKAQTKRSSLMMSFMRPGTAEGGWSNMMGVFQRNTSPTSPVENTVARTVPLSFASTITQHESPPSSPTLSPKKKEAEIMFDGDDIFDADTLLEEKDQHQKDDTQPKKPSQARIDSSFFDDDEEDENQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N9E6</accession>
    <name>A0A1C7N9E6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">SWR1-complex protein 4</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">swc4</name>
        <name evidence="11" type="ORF">A0J61_06703</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Component of the SWR1 complex which mediates the ATP-dependent exchange of histone H2A for the H2A variant HZT1 leading to transcriptional regulation of selected genes by chromatin remodeling. Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histone H4 and H2A. The NuA4 complex is also involved in DNA repair.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SWC4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000418">
        <property type="protein sequence ID" value="OBZ85246.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N9E6"/>
    <dbReference type="FunCoup" id="A0A1C7N9E6">
        <property type="interactions" value="676"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N9E6"/>
    <dbReference type="InParanoid" id="A0A1C7N9E6"/>
    <dbReference type="OrthoDB" id="19740at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035267">
        <property type="term" value="C:NuA4 histone acetyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000812">
        <property type="term" value="C:Swr1 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003714">
        <property type="term" value="F:transcription corepressor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006338">
        <property type="term" value="P:chromatin remodeling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000122">
        <property type="term" value="P:negative regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.60:FF:000087">
        <property type="entry name" value="DNA methyltransferase 1-associated protein 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032563">
        <property type="entry name" value="DAMP1_SANT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008468">
        <property type="entry name" value="DMAP1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001005">
        <property type="entry name" value="SANT/Myb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027109">
        <property type="entry name" value="Swc4/Dmap1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12855:SF10">
        <property type="entry name" value="DNA METHYLTRANSFERASE 1-ASSOCIATED PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12855">
        <property type="entry name" value="DNA METHYLTRANSFERASE 1-ASSOCIATED PROTEIN 1 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05499">
        <property type="entry name" value="DMAP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16282">
        <property type="entry name" value="SANT_DAMP1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00717">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0804">Transcription</keyword>
    <keyword evidence="5" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Myb-like" evidence="10">
        <location>
            <begin position="140"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="279"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="320"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="413"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="279"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="290"/>
            <end position="299"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00019132"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00025264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM00717"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="OBZ85246.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="452" mass="50984" checksum="3E0FD34ACFACD472" modified="2016-11-30" version="1">MHIRAKILKYQLNNCIYNMSSSDIRDILQISQSTEPAPKRTKQPAEKRPDGISRELYSLIGGAPPVAFVKPTFKAKYQKKKKAVPWKMQPFTNPARGDGLLLSHWVKASEADNQDYPFAKFNKVIDVLSYSDEDYEKYLTDTDWSKEETDYLFDLCRQYDLRFPVIEDRYNFGSKPRTIEDLKDRYYTVYRKMILQGKGPISGDYVSDRQSLAQQYAFDKAKEVERKNALIMLFNRTKEQVEEEEALFVEAKRIALNEARLSRERESLLNSLQLEQIQQMPSTPNTPLNASPASAASGSNMGGVSGSHIIASSPGGIGITGGTAGGSSDLKKKKKITSDVHDTKKEKLVPGVYVRSQKLPIVKPTMQPKVIKILEELGIGPRPIMPTSQICQRFEALQNSILNLLELKKVADKTETEHKVKIHKGRDTTPVGRKRSGSNAGVSNANRDKRRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N9W5</accession>
    <name>A0A1C7N9W5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Myb-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_06500</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000394">
        <property type="protein sequence ID" value="OBZ85459.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N9W5"/>
    <dbReference type="InParanoid" id="A0A1C7N9W5"/>
    <dbReference type="OrthoDB" id="2289901at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001005">
        <property type="entry name" value="SANT/Myb"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13921">
        <property type="entry name" value="Myb_DNA-bind_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50090">
        <property type="entry name" value="MYB_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Myb-like" evidence="2">
        <location>
            <begin position="67"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="18"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="23"/>
            <end position="48"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ85459.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="127" mass="14708" checksum="49553E04C2ED3BAE" modified="2016-11-30" version="1">MWHEKDIDPVAINSFNDMRISGPASTSQDTSSNHYSTLFEPSSSQSQPARLPPPTKYDQDIRGYELWTHEDDILLLSYVLYSLRGGGWSELEARFNGRHSARLCYDRWKYLKSLLLKNLLDKPNATW</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NC18</accession>
    <name>A0A1C7NC18_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Protein ORM1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">A0J61_05288</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000282">
        <property type="protein sequence ID" value="OBZ86662.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NC18"/>
    <dbReference type="STRING" id="101091.A0A1C7NC18"/>
    <dbReference type="InParanoid" id="A0A1C7NC18"/>
    <dbReference type="OrthoDB" id="1932233at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007203">
        <property type="entry name" value="ORMDL"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12665">
        <property type="entry name" value="ORMDL PROTEINS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04061">
        <property type="entry name" value="ORMDL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="52"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OBZ86662.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="89" mass="10135" checksum="242582F65AF906BC" modified="2016-11-30" version="1" fragment="single">GIPFENNQGAYDGLTLWEQIDGGVQFTATRKFLTAVPIVLFLLSTHYTHYDVFLFGINFTALLVVLVAKLPVMHRVRIFGINKLDYEMD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NCX2</accession>
    <name>A0A1C7NCX2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">3-hydroxyacyl-CoA dehydrogenase type-2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">HSD17B10</name>
        <name evidence="4" type="ORF">A0J61_05532</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000301">
        <property type="protein sequence ID" value="OBZ86416.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NCX2"/>
    <dbReference type="STRING" id="101091.A0A1C7NCX2"/>
    <dbReference type="InParanoid" id="A0A1C7NCX2"/>
    <dbReference type="OrthoDB" id="3819888at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43658:SF8">
        <property type="entry name" value="17-BETA-HYDROXYSTEROID DEHYDROGENASE 14-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43658">
        <property type="entry name" value="SHORT-CHAIN DEHYDROGENASE/REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0521">NADP</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU000363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OBZ86416.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="255" mass="27217" checksum="09B9C02643DD3A43" modified="2016-11-30" version="1">MQIEGNLFIVTGGASGLGEDVARHLVQQGAFVSIFDINQERAESIVNELGQEKCFSPGLTDVTQEANVIESMSRTLAHFSQIALAGAILCSGIVHPPKSLEGYGDQKALTSFAQFEHVIKVNLLGTYCVAQKVAEQLVSNQPFNQDQEKGIIITASSMLGLDGALVGYGTSKAGIIGFTLPMARELASHGIRVMSIAPGPFDTPMVDRNASTPTPTALFPSRYGAPAEFTQLVVEIIRNRMLNGSVIRLDGALRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NCY8</accession>
    <name>A0A1C7NCY8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_06721</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000420">
        <property type="protein sequence ID" value="OBZ85224.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NCY8"/>
    <dbReference type="STRING" id="101091.A0A1C7NCY8"/>
    <dbReference type="InParanoid" id="A0A1C7NCY8"/>
    <dbReference type="OrthoDB" id="2271284at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ85224.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="125" mass="14416" checksum="80EC7565E0FB16B6" modified="2016-11-30" version="1">MINQERSYIIRWHLGWLPHGCPSSYPLLSDHPFTRARAIHCLQIHNRLEMPLPVEDPLSFLLNILPTKKLRSPLESSPWIIRWPVICHTLHGMDYLAHSTTPTPNDPGPLLLQWLLPLSDNAHIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7ND73</accession>
    <name>A0A1C7ND73_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">60S ribosome subunit biogenesis protein NIP7</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">nip7</name>
        <name evidence="9" type="ORF">A0J61_04965</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6 7">Required for proper 27S pre-rRNA processing and 60S ribosome subunit assembly.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Interacts with pre-ribosome complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the NIP7 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000255">
        <property type="protein sequence ID" value="OBZ86988.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7ND73"/>
    <dbReference type="FunCoup" id="A0A1C7ND73">
        <property type="interactions" value="476"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7ND73"/>
    <dbReference type="InParanoid" id="A0A1C7ND73"/>
    <dbReference type="OrthoDB" id="27490at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030687">
        <property type="term" value="C:preribosome, large subunit precursor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902626">
        <property type="term" value="P:assembly of large subunit precursor of preribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000463">
        <property type="term" value="P:maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd21146">
        <property type="entry name" value="Nip7_N_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd21151">
        <property type="entry name" value="PUA_Nip7-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.130.10:FF:000002">
        <property type="entry name" value="60S ribosome subunit biogenesis protein NIP7 homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.450.220:FF:000001">
        <property type="entry name" value="60S ribosome subunit biogenesis protein NIP7 homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.450.220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.130.10">
        <property type="entry name" value="PUA domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040598">
        <property type="entry name" value="NIP7_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055359">
        <property type="entry name" value="Nip7_N_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002478">
        <property type="entry name" value="PUA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015947">
        <property type="entry name" value="PUA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036974">
        <property type="entry name" value="PUA_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016686">
        <property type="entry name" value="Ribosomal_synth_fac_NIP7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005155">
        <property type="entry name" value="UPF0113_PUA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23415">
        <property type="entry name" value="CYCLIN-DEPENDENT KINASES REGULATORY SUBUNIT/60S RIBOSOME SUBUNIT BIOGENESIS PROTEIN NIP7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17833">
        <property type="entry name" value="pre-PUA_NIP7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03657">
        <property type="entry name" value="UPF0113"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF017190">
        <property type="entry name" value="Rbsml_synth_fac_NIP7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00359">
        <property type="entry name" value="PUA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88802">
        <property type="entry name" value="Pre-PUA domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88697">
        <property type="entry name" value="PUA domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50890">
        <property type="entry name" value="PUA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="4 7" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="PUA" evidence="8">
        <location>
            <begin position="95"/>
            <end position="170"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009895"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00054591"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRNR" id="PIRNR017190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OBZ86988.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="180" mass="20475" checksum="C7B48C6A184DA184" modified="2016-11-30" version="1">MRPLTSEETTALFEKLAKYIGANIKHLIDRPDETYCFRLQKNKVYYLSESMMRMAVSVGRDQLGSVGVCFGKFSKTGKFKLHITALDHLAQYAQHKIWIKPNGEMPFLYGNHIVKAHLGRITDDTPEHTGVVIFSMSDSPLGFGVTARSTMEMKKLQPTDIIVFHQADVGEYLREEDTLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NDA2</accession>
    <name>A0A1C7NDA2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">3-hydroxyanthranilate 3,4-dioxygenase</fullName>
            <ecNumber evidence="8">1.13.11.6</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">3-hydroxyanthranilate oxygenase</fullName>
            <shortName evidence="8">3-HAO</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">3-hydroxyanthranilic acid dioxygenase</fullName>
            <shortName evidence="8">HAD</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">Biosynthesis of nicotinic acid protein 1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8 9" type="primary">BNA1</name>
        <name evidence="9" type="ORF">A0J61_04886</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 8">Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>3-hydroxyanthranilate + O2 = (2Z,4Z)-2-amino-3-carboxymuconate 6-semialdehyde</text>
            <dbReference type="Rhea" id="RHEA:17953"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:36559"/>
            <dbReference type="ChEBI" id="CHEBI:77612"/>
            <dbReference type="EC" id="1.13.11.6"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 8">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="8">Cofactor biosynthesis; NAD(+) biosynthesis; quinolinate from L-kynurenine: step 3/3.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the 3-HAO family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.13.11.6" evidence="8"/>
    <dbReference type="EMBL" id="LUGH01000250">
        <property type="protein sequence ID" value="OBZ87055.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NDA2"/>
    <dbReference type="STRING" id="101091.A0A1C7NDA2"/>
    <dbReference type="InParanoid" id="A0A1C7NDA2"/>
    <dbReference type="OrthoDB" id="204928at2759"/>
    <dbReference type="UniPathway" id="UPA00253">
        <property type="reaction ID" value="UER00330"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000334">
        <property type="term" value="F:3-hydroxyanthranilate 3,4-dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008198">
        <property type="term" value="F:ferrous iron binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034354">
        <property type="term" value="P:'de novo' NAD+ biosynthetic process from L-tryptophan"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043420">
        <property type="term" value="P:anthranilate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006569">
        <property type="term" value="P:L-tryptophan catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019805">
        <property type="term" value="P:quinolinate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd06123">
        <property type="entry name" value="cupin_HAO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="entry name" value="Jelly Rolls"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00825">
        <property type="entry name" value="3_HAO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010329">
        <property type="entry name" value="3hydroanth_dOase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR03037">
        <property type="entry name" value="anthran_nbaC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF009763">
        <property type="entry name" value="PRK13264.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15497">
        <property type="entry name" value="3-HYDROXYANTHRANILATE 3,4-DIOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15497:SF1">
        <property type="entry name" value="3-HYDROXYANTHRANILATE 3,4-DIOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06052">
        <property type="entry name" value="3-HAO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="RmlC-like cupins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 8 9" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="7 8" id="KW-0408">Iron</keyword>
    <keyword evidence="4 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3 8" id="KW-0662">Pyridine nucleotide biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="8">
        <location>
            <position position="45"/>
        </location>
        <ligand>
            <name>O2</name>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="49"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="55"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="55"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="93"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="97"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="107"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="122"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="127"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="161"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="164"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002752"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OBZ87055.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="171" mass="19814" checksum="4C7226B80A32F0D7" modified="2016-11-30" version="1">MLPPPINFQKWVAENSDKLQPPVNNSILFRGKDTLVMVVGGPNKRTDYHINETEEWFYQVKGQLLIKVVDDGEFKDIHVQEGDMFLLPPNTPHNPVRYENTIGLVIERVRLSHHVDILRWYCENEACRQVVYEESFHCVDLGTQLKPIIEKFASTKELRVCKHCGQLNSAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NDV9</accession>
    <name>A0A1C7NDV9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Proteasome subunit beta</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">PRE2</name>
        <name evidence="12" type="ORF">A0J61_04650</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Cleavage of peptide bonds with very broad specificity.</text>
            <dbReference type="EC" id="3.4.25.1"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="11">Component of the proteasome complex.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits. The 20S proteasome core is composed of 28 subunits that are arranged in four stacked rings, resulting in a barrel-shaped structure. The two end rings are each formed by seven alpha subunits, and the two central rings are each formed by seven beta subunits. The catalytic chamber with the active sites is on the inside of the barrel.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="11">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="11">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="11">Belongs to the peptidase T1B family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000232">
        <property type="protein sequence ID" value="OBZ87293.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NDV9"/>
    <dbReference type="FunCoup" id="A0A1C7NDV9">
        <property type="interactions" value="222"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NDV9"/>
    <dbReference type="InParanoid" id="A0A1C7NDV9"/>
    <dbReference type="OrthoDB" id="37597at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005777">
        <property type="term" value="C:peroxisome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019774">
        <property type="term" value="C:proteasome core complex, beta-subunit complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004298">
        <property type="term" value="F:threonine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010499">
        <property type="term" value="P:proteasomal ubiquitin-independent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0080129">
        <property type="term" value="P:proteasome core complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043161">
        <property type="term" value="P:proteasome-mediated ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd03761">
        <property type="entry name" value="proteasome_beta_type_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.20.10:FF:000013">
        <property type="entry name" value="Proteasome subunit beta type-5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.10">
        <property type="entry name" value="Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000243">
        <property type="entry name" value="Pept_T1A_subB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016050">
        <property type="entry name" value="Proteasome_bsu_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001353">
        <property type="entry name" value="Proteasome_sua/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023333">
        <property type="entry name" value="Proteasome_suB-type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32194">
        <property type="entry name" value="METALLOPROTEASE TLDD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32194:SF3">
        <property type="entry name" value="PROTEASOME SUBUNIT BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00227">
        <property type="entry name" value="Proteasome"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00141">
        <property type="entry name" value="PROTEASOME"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="N-terminal nucleophile aminohydrolases (Ntn hydrolases)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00854">
        <property type="entry name" value="PROTEASOME_BETA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51476">
        <property type="entry name" value="PROTEASOME_BETA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 11" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8 11" id="KW-0539">Nucleus</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="6 11 12" id="KW-0647">Proteasome</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0888">Threonine protease</keyword>
    <keyword evidence="7" id="KW-0865">Zymogen</keyword>
    <feature type="active site" description="Nucleophile" evidence="10">
        <location>
            <position position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022698"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00026071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR600243-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU004203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="OBZ87293.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="277" mass="30677" checksum="A8B3AFA8D86BCC1E" modified="2016-11-30" version="1">MNRFVSKYSVSPLTLPREENFSQLCGKWDAAQELAFPAFDIPAIHNPVDFLKNVTDESSPDYKIKIQHGTTTLAFQFQGGVVVAVDSRATMGNYIGSQTVKKVIEINPYLLGTMAGGAADCSYWERELGRRCRLHELRNKERISVAAASKLLANMVYSYKGMGLSMGTMVTGWDKSGPNLFYVDSDGTRLKGDIFSVGSGSTFAYGVLDTGYDYDLSVKDALELGRRSIYHATHRDAMSGGSVNLYHVTEEGWTYHGNHDVGQLHWDYQDGVAKDII</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NET5</accession>
    <name>A0A1C7NET5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="1">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">CIPK11</name>
        <name evidence="12" type="ORF">A0J61_04898</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="1"/>
    <dbReference type="EMBL" id="LUGH01000250">
        <property type="protein sequence ID" value="OBZ87066.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NET5"/>
    <dbReference type="STRING" id="101091.A0A1C7NET5"/>
    <dbReference type="InParanoid" id="A0A1C7NET5"/>
    <dbReference type="OrthoDB" id="289250at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000042">
        <property type="entry name" value="Aurora kinase A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000571">
        <property type="entry name" value="Maternal embryonic leucine zipper kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43895">
        <property type="entry name" value="CALCIUM/CALMODULIN-DEPENDENT PROTEIN KINASE KINASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43895:SF32">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE CHK1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 12" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="11">
        <location>
            <begin position="241"/>
            <end position="511"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="25"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="120"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="25"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="39"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="131"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="270"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="OBZ87066.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="519" mass="59380" checksum="3F9F183526412ECC" modified="2016-11-30" version="1">MTTLQKSLLIPDNSDNLQNESLNHRREASRGLEIDTGKTKTNAFFHTSDLSSSTPRPPPSISRKISVKQNQPKPTLSKPLPTPPSPTITIPDNNDDDEDLYHYDSYSNRLRNLVASNRHYQHQQPSPIPNHLNTSNKQQQQSPTTPNFLLNVEDLVALPTPHVKENVQRKAHFVFPTSAQIQEIPVFNTILNPIQHHGTPVLSEQPMLGDSLSIPSSSNLNREKNLYLQDQDIVGKQLGPYRVCQLLGVGAFSKVYLANHVETQKFFAIKTIQKGTLFDDPRVRSSIEREVGILKYIDNPNIVHLEATMETEHMMCIVLEYVEGGELFDYVQKMHHTAHTKVDEDMIKAIFLQLVQAVQWLHDHNIVHRDLKLENILIHNNKDETPKLKITDFGLARVVDPESPLLTTRCGSEEYAAPEIIQQQPYDGRKTDTWALGIILYSLLVGYLPFRYDPRKQERVSQLFYRIVRAQVKWPTDCQLSEEAKQAVHCILERNPQKRICLDQIQHLPWFSNTHHSSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NF97</accession>
    <name>A0A1C7NF97_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Cysteine and glycine-rich protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">Csrp1</name>
        <name evidence="8" type="ORF">A0J61_04201</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000199">
        <property type="protein sequence ID" value="OBZ87757.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NF97"/>
    <dbReference type="STRING" id="101091.A0A1C7NF97"/>
    <dbReference type="InParanoid" id="A0A1C7NF97"/>
    <dbReference type="OrthoDB" id="1112565at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003712">
        <property type="term" value="F:transcription coregulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd08368">
        <property type="entry name" value="LIM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.110.10">
        <property type="entry name" value="Cysteine Rich Protein"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036280">
        <property type="entry name" value="Multihaem_cyt_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001781">
        <property type="entry name" value="Znf_LIM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24205">
        <property type="entry name" value="FOUR AND A HALF LIM DOMAINS PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24205:SF16">
        <property type="entry name" value="GH01042P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00412">
        <property type="entry name" value="LIM"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00132">
        <property type="entry name" value="LIM"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48695">
        <property type="entry name" value="Multiheme cytochromes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00478">
        <property type="entry name" value="LIM_DOMAIN_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50023">
        <property type="entry name" value="LIM_DOMAIN_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0440">LIM domain</keyword>
    <keyword evidence="1 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 5" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="LIM zinc-binding" evidence="7">
        <location>
            <begin position="151"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="domain" description="LIM zinc-binding" evidence="7">
        <location>
            <begin position="431"/>
            <end position="491"/>
        </location>
    </feature>
    <feature type="domain" description="LIM zinc-binding" evidence="7">
        <location>
            <begin position="535"/>
            <end position="601"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="63"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="215"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="385"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="65"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="90"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="218"/>
            <end position="245"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023038"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OBZ87757.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="605" mass="67289" checksum="7D98789171D90830" modified="2016-11-30" version="1">MGFCIYCNQNVYSNTTCPKCYRTISKQPASAEGSKAPFPSQKILSQAMSDKWQDTYGKKAIFNSGLGSPTSSTSKPNLTRPQRKMPQFSRPESPQQARSPQQARSPKTIDKSQLSSNTKCCAHCQQPQNSWADLTMYNSLHYCKTCLEQKLACPGCHQPVNRTDAQAYFRDQVWHASCFQCNYCKNPLKTMLATVDSEGKPCCRSCQLTEVNRLQQMPSPGSPSVSTPLLPSLTSSRSTTVTSSSKPGENPYFQLKRSRRTSMFSSPSEEESKRHTLDSITQRIAAAAAAQAESQPTSPVKETKEKTTRRKKVLKKPCNECGQRVTKKEYRGLKIPTGEVLCFHSHCLHCAKCNQSFNSLDFCTDGKSFYHVECAGAHTAVVPPRQNTPLSEDEAFPRTPSPQNAHFDVLPTESPTSFMEEDHTKEAKTTVLCSTCQEPVTDTCLELANNFYHAKCLLCAGCNKTVPTDRKLSKIQGKLYCDHCSTTKKRASAPGLKIVTQQKTGETMPKRHSITTPSDIFKSRTKGLPRLGGVRTCARCNESMPFSDTQPGPNASRWHKKCLRCSGCNKQMDSDAHMTVNEETGLCLVHCRECLDETPKPKFVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NFC6</accession>
    <name>A0A1C7NFC6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Sphingolipid long chain base-responsive protein LSP1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">LSP1</name>
        <name evidence="2" type="ORF">A0J61_04162</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000197">
        <property type="protein sequence ID" value="OBZ87787.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NFC6"/>
    <dbReference type="STRING" id="101091.A0A1C7NFC6"/>
    <dbReference type="InParanoid" id="A0A1C7NFC6"/>
    <dbReference type="OrthoDB" id="5599269at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036286">
        <property type="term" value="C:eisosome filament"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008289">
        <property type="term" value="F:lipid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070941">
        <property type="term" value="P:eisosome assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006897">
        <property type="term" value="P:endocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.60">
        <property type="entry name" value="Arfaptin homology (AH) domain/BAR domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027267">
        <property type="entry name" value="AH/BAR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028245">
        <property type="entry name" value="PIL1/LSP1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31962">
        <property type="entry name" value="SPHINGOLIPID LONG CHAIN BASE-RESPONSIVE PROTEIN PIL1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31962:SF1">
        <property type="entry name" value="SPHINGOLIPID LONG CHAIN BASE-RESPONSIVE PROTEIN PIL1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13805">
        <property type="entry name" value="Pil1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="232"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="296"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="399"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="402"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="432"/>
            <end position="449"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ87787.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="456" mass="51674" checksum="A421334EB42F2FD0" modified="2016-11-30" version="1">MFGLFHKSSDKTVSEKGLSNVIDYTGKSSRDVAHLADNNRISANNLMAYGSHIGDDLTDVTHKLGQLLTEWSNVLMEFSDTMDQYRDTLKSISIKEQALQPSRDQKRKLQESIERLQSSYNSLDKLNALKAQLKELEEFTEVDEVEMANFKRIATREGLYILLNGMHAMASKTDIVSTFGKYIVDELDVAPIQPHQTRPEYQGAEKTKRIQEDALRAIEMWKPDQAKVRRTLTSHHGKNPLLVKRVDSVAPTPPPKDIQTEGEAVEIPDRIGSLENPEHSYYKPDEMEQPLVEEAEELPEEAVDQEEKKDQENEDNQYQPPSEPMMPHPSVLLSPAANTALSNTGMSPMTANNALHPPHPYYYQHQPAFNQHNLYQFYQHYLPPRSYEEMSSTLSPVFRGSSHLEDEAPSSHHQDAGGFVLPSDNPNYYLHGNNSRRPSATSSVRSNPASHHEEET</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NFN0</accession>
    <name>A0A1C7NFN0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative arrestin-related trafficking adapter C2D10.04</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_04071</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000191">
        <property type="protein sequence ID" value="OBZ87887.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NFN0"/>
    <dbReference type="STRING" id="101091.A0A1C7NFN0"/>
    <dbReference type="InParanoid" id="A0A1C7NFN0"/>
    <dbReference type="OrthoDB" id="2333384at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030674">
        <property type="term" value="F:protein-macromolecule adaptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031625">
        <property type="term" value="F:ubiquitin protein ligase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070086">
        <property type="term" value="P:ubiquitin-dependent endocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.640">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014752">
        <property type="entry name" value="Arrestin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011021">
        <property type="entry name" value="Arrestin-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050357">
        <property type="entry name" value="Arrestin_domain-protein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11188">
        <property type="entry name" value="ARRESTIN DOMAIN CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11188:SF17">
        <property type="entry name" value="FI21816P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00339">
        <property type="entry name" value="Arrestin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="E set domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Arrestin-like N-terminal" evidence="2">
        <location>
            <begin position="36"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="412"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="419"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="435"/>
            <end position="444"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ87887.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="444" mass="49638" checksum="9F7BB60A3C670F04" modified="2016-11-30" version="1">MPVVVPFFTGAKQLTIELAEPVVILRGSPADNITHVLQGEVSVVLTRPVSISQVVVQFIGKTTRLWPEGLAGGRLTNSFHERTIHEQDVILQSFPENPKQEGVLPAGTHRWPFQFLLSSYLAETIEDQMGQVFYYIVATVHRVGVGATKLRSRYDVLLLRTPNWSDNALAGNSLPTTSITSERQLDICDANICIEKSIVAGGAQLPISFCISPNMKHVFIESMTVILREKKVYRMPELHARRSESYDYKVTLHSICEPSSSSLESGSKPAMSLKDLKKALGLKNAHISLNENPFQHRIIFNLPGCMRLNHSTTYSEIDIQHTLKVHIELSSPFDANSNDTAKTDICFETPFTVLDCRLKEDCSALPTYEQAMLDDSAVDHQDLPSDSNPTNFFPCPCYLEYKKKRNVTRRDWIKFRNESTQSPTSPSSLPSSSSIPPPPSYDSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NGF0</accession>
    <name>A0A1C7NGF0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_03831</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000174">
        <property type="protein sequence ID" value="OBZ88115.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NGF0"/>
    <dbReference type="InParanoid" id="A0A1C7NGF0"/>
    <dbReference type="OrthoDB" id="10257471at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12937">
        <property type="entry name" value="F-box-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="2">
        <location>
            <begin position="127"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="26"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="52"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12937"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ88115.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="516" mass="59338" checksum="88AE484FA639B7E3" modified="2016-11-30" version="1">MSIQRTPLEEKSVNSKSNQISPPPKLDNHALEKMQRLKPYGWSPLRSKKNNKKPDNIEEKSSQSPPESSKDIPSPTPSPTTSCNISPKTKKRTLVRLGSRKNENAKGDQQNGFADEYDVPISRLSVDCLLAIFAYCECFENYCTLLQVCSTWRAIASQPIIWRKVHTNWSALNRQIKALHSPRRRFDQLHYIRSLSILNDKQEMPLFATDIRIPPFDQLKELQLTSMYLADIDRLISWLDCLTTLVCQKTLVGQRPTLRLSMFSRLRQLEHLAIDFYVPCCLGFNRATAFLNSDRNLLSERLPESLKTFSLHGVYDSEELLFDVQLRDLFHDVPVLPDRRRTRQAEAMRIITQHQDEIANQDDMIANWIEMERTMVLKYNVLSCLTQLTSLSLGSVRSFTSRVWRECMIPCAGNLNYLSLAAWNGKRENPQLTVQRLLQPDLKDDAEEALAEFTSALKNIKLIELDRFVCSQGLINGLKQIQRPLSITHKLDATPKTTMDHLINSTLHQCKITWAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NHQ8</accession>
    <name>A0A1C7NHQ8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_05069</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000264">
        <property type="protein sequence ID" value="OBZ86884.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NHQ8"/>
    <dbReference type="InParanoid" id="A0A1C7NHQ8"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="40"/>
            <end position="69"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ86884.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="75" mass="8640" checksum="2CE7C3E95239CA60" modified="2016-11-30" version="1">MLNQPDMKRIPPSIIFSVVDDGIFTRIQEMTIRSKGRRELLNWIIALFTLVRPLQTFNITMLSPSIIIIPEGKSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NHR5</accession>
    <name>A0A1C7NHR5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">G1/S-specific cyclin pas1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_03270</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000138">
        <property type="protein sequence ID" value="OBZ88672.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NHR5"/>
    <dbReference type="STRING" id="101091.A0A1C7NHR5"/>
    <dbReference type="InParanoid" id="A0A1C7NHR5"/>
    <dbReference type="OrthoDB" id="244495at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000307">
        <property type="term" value="C:cyclin-dependent protein kinase holoenzyme complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016538">
        <property type="term" value="F:cyclin-dependent protein serine/threonine kinase regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019901">
        <property type="term" value="F:protein kinase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.10">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013922">
        <property type="entry name" value="Cyclin_PHO80-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15615">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15615:SF27">
        <property type="entry name" value="PHO85 CYCLIN CLG1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="58"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ88672.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="163" mass="18456" checksum="4A66B4CCAF359BF2" modified="2016-11-30" version="1" fragment="single">TWSEVSSIPVNELNIMEMEFLSALNYTIHLPQDDFYAWVNQCQQWWNRPQLAESQNDFAAYTTAAATAMMVAAAAAAAAAINHHTPTIHSSSPPIRMKRSFDEEQPHYKKRFTDYNVCKPILSWSSSIPISQPDPYSTPTTPANTNIYHYLPFVSTIESDILK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NHY8</accession>
    <name>A0A1C7NHY8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Zinc finger protein GLIS3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">Glis3</name>
        <name evidence="12" type="ORF">A0J61_03347</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the GLI C2H2-type zinc-finger protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000142">
        <property type="protein sequence ID" value="OBZ88610.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NHY8"/>
    <dbReference type="STRING" id="101091.A0A1C7NHY8"/>
    <dbReference type="InParanoid" id="A0A1C7NHY8"/>
    <dbReference type="OrthoDB" id="654211at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:002343">
        <property type="entry name" value="Zinc finger protein 33A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043359">
        <property type="entry name" value="GLI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056436">
        <property type="entry name" value="Znf-C2H2_ZIC1-5/GLI1-3-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45718:SF8">
        <property type="entry name" value="GLIS FAMILY ZINC FINGER 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45718">
        <property type="entry name" value="TRANSCRIPTIONAL ACTIVATOR CUBITUS INTERRUPTUS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23561">
        <property type="entry name" value="zf-C2H2_15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <keyword evidence="5 9" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="11">
        <location>
            <begin position="378"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="11">
        <location>
            <begin position="411"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="11">
        <location>
            <begin position="441"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="216"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="298"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="216"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="10">
        <location>
            <begin position="238"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="302"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="331"/>
            <end position="343"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010831"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="OBZ88610.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="526" mass="59655" checksum="2708A8E0CEBD5E9C" modified="2016-11-30" version="1">MMPHYNTMMVPTTTTMASHEYIETQNNTMFPINNNFYAPHITATPVVKSHNPISVFTSPIGAVPLPQQQQQQQQQITSLDLSTTNMMMNAMEIDDYFAGNSNMFNMYSPSSTTTNNSSVMMMDNNMSPTSPTPNGIMHPPSLDSFVAPQSGFHQQMMMDRIDPSMFPIPMPSMPHSMPFQVQDDQRLMYPPPTPHVQPYMNNARRTMPRRHTVSTPYATHTLTTPSSKNKPSEPPITKSRKSSLKAKRHRSLGKIDIYTSTTSPSSPPPIPDLLSTKLELWTHEQLLERVMELEKEREVVQGSASSNTDEIGHLNTTTGNKARSASHTDTELEEENDEEEEDEPQVCKWEDCLLELKSLEDLIQHVKTVHIGSGKANYYCNWKDCPRKQKPFTKRHKMHNHLRTHTGERPFVCQEPDCGKKFSRPDSLTTHAKIHSNIRPYLCKNADCGKAYYHLRSLRKHERTHMQQAMSCSSSPPPLPVAHVPASHSNELQLLQPMKNDILSDWGISAQAAVFDVMNRESNAYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NI16</accession>
    <name>A0A1C7NI16_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 12">Malate dehydrogenase</fullName>
            <ecNumber evidence="3 12">1.1.1.37</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="primary">MDH1</name>
        <name evidence="15" type="ORF">A0J61_03188</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7 12">
            <text>(S)-malate + NAD(+) = oxaloacetate + NADH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:21432"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15589"/>
            <dbReference type="ChEBI" id="CHEBI:16452"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.1.1.37"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="2">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the LDH/MDH superfamily. MDH type 1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.37" evidence="3 12"/>
    <dbReference type="EMBL" id="LUGH01000133">
        <property type="protein sequence ID" value="OBZ88767.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NI16"/>
    <dbReference type="FunCoup" id="A0A1C7NI16">
        <property type="interactions" value="681"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NI16"/>
    <dbReference type="InParanoid" id="A0A1C7NI16"/>
    <dbReference type="OrthoDB" id="4069699at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030060">
        <property type="term" value="F:L-malate dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006108">
        <property type="term" value="P:malate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01337">
        <property type="entry name" value="MDH_glyoxysomal_mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000013">
        <property type="entry name" value="Malate dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.110.10:FF:000001">
        <property type="entry name" value="Malate dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.110.10">
        <property type="entry name" value="Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001557">
        <property type="entry name" value="L-lactate/malate_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022383">
        <property type="entry name" value="Lactate/malate_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001236">
        <property type="entry name" value="Lactate/malate_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015955">
        <property type="entry name" value="Lactate_DH/Glyco_Ohase_4_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001252">
        <property type="entry name" value="Malate_DH_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010097">
        <property type="entry name" value="Malate_DH_type1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01772">
        <property type="entry name" value="MDH_euk_gproteo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11540">
        <property type="entry name" value="MALATE AND LACTATE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11540:SF16">
        <property type="entry name" value="MALATE DEHYDROGENASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02866">
        <property type="entry name" value="Ldh_1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00056">
        <property type="entry name" value="Ldh_1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000102">
        <property type="entry name" value="Lac_mal_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56327">
        <property type="entry name" value="LDH C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00068">
        <property type="entry name" value="MDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 10 12" id="KW-0520">NAD</keyword>
    <keyword evidence="5 11" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 12" id="KW-0816">Tricarboxylic acid cycle</keyword>
    <feature type="domain" description="Lactate/malate dehydrogenase N-terminal" evidence="13">
        <location>
            <begin position="25"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="domain" description="Lactate/malate dehydrogenase C-terminal" evidence="14">
        <location>
            <begin position="170"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="8">
        <location>
            <position position="200"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="30"/>
            <end position="36"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="56"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="104"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="110"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="117"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="140"/>
            <end position="142"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="142"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="176"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="249"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00048313"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR000102-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR000102-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR000102-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU003369"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU003405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF00056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF02866"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="OBZ88767.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="337" mass="35585" checksum="64DE7795E69DCE12" modified="2016-11-30" version="1">MLASRLFKSVAAKRAFSTSAANLSKVAVLGAAGGIGQPLSLLLKENPHVTHLSLYDIVNTPGVAADLSHINTNSKVTGHTPENEGLKAALEGAHVVVIPAGVPRKPGMTRDDLFNTNASIVRDLATAAAKYCPDAHFLIISNPVNSTVPIFAETLKKAGVFNEKRLYGVTTLDVVRASRFVAEVKNLDPKDVNVTVVGGHSGVTIVPLLSQTGIEFTKEELDALTHRIQFGGDEVVKAKNGTGSATLSMAYAGARMANSVLEATVGGKKGVVEPSFVKSDVFAAEGVEYFSTNIELGPEGVEKIHGLGEISDYEKELISKAVPELKKNIEKGNSFVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NIY5</accession>
    <name>A0A1C7NIY5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">PRKR-interacting protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">PRKRIP1</name>
        <name evidence="2" type="ORF">A0J61_02836</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000113">
        <property type="protein sequence ID" value="OBZ89102.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NIY5"/>
    <dbReference type="STRING" id="101091.A0A1C7NIY5"/>
    <dbReference type="InParanoid" id="A0A1C7NIY5"/>
    <dbReference type="OrthoDB" id="10067079at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003725">
        <property type="term" value="F:double-stranded RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019901">
        <property type="term" value="F:protein kinase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004860">
        <property type="term" value="F:protein kinase inhibitor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009548">
        <property type="entry name" value="Prkrip1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13507">
        <property type="entry name" value="PRKR-INTERACTING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13507:SF0">
        <property type="entry name" value="PRKR-INTERACTING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06658">
        <property type="entry name" value="DUF1168"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="85"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="85"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="116"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="129"/>
            <end position="150"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ89102.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="157" mass="18652" checksum="3CEFDB0EBEC11DF7" modified="2016-11-30" version="1">MATQIEPEKKKNKYNLTPQEEQQEKLNRLFEKIDKPVFIPNKQEDKAFVPPPKDFVRNVAGSSAGAGSGDFHVYRAQRRREYARLKVMEDEEKKAKQREYEEKLKRLRQADEERTAKKRAKRQKRSKNKKDTKEKKDTDDDTVKDTKEDSPEQQQQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NJ04</accession>
    <name>A0A1C7NJ04_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_02963</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000120">
        <property type="protein sequence ID" value="OBZ88978.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NJ04"/>
    <dbReference type="InParanoid" id="A0A1C7NJ04"/>
    <dbReference type="OrthoDB" id="10594385at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="14"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ88978.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="66" mass="7606" checksum="0A5265A54BB0BF7C" modified="2016-11-30" version="1">MSFINKFIDKAKGSRQTQQATDSQPREIPSSTHEKTSSQQDGKDEDLEELIESLQQLKKEKCTYNM</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NJE9</accession>
    <name>A0A1C7NJE9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">SAP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_02698</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000105">
        <property type="protein sequence ID" value="OBZ89247.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NJE9"/>
    <dbReference type="InParanoid" id="A0A1C7NJE9"/>
    <dbReference type="OrthoDB" id="5576441at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd22999">
        <property type="entry name" value="SAP_SLX4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003034">
        <property type="entry name" value="SAP_dom"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50800">
        <property type="entry name" value="SAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SAP" evidence="1">
        <location>
            <begin position="192"/>
            <end position="226"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50800"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ89247.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="318" mass="36808" checksum="23CDC035227B47BB" modified="2016-11-30" version="1">MAPKRKAETSLDSTQKKQCREICSLCLQPCAITPFPTHLYFSLALIPSRSDRALSLFEKESDDIQYLAHCLHQLADQPDLFKSVITRFRHLLETKKIEEYRTLLSKEHRIDGTREYAFLVHLVDQLESRISTLLRLLSDPISSLDTFFLIEVTLTRALAILTVAHKIKKETEQLELVDISNHPPRPVSMPDYDALSTPELRAKLKSYGYKSGGRRAQMIEDLKNIFQSLHQSTATVRSNQTDTEYVTTKEQLNPETRHKIVKHLKENTSRWNQILRYENQQVNINECHLGLDCKKSELKIVLDEYAAGNDFKKTRKKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NJH1</accession>
    <name>A0A1C7NJH1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">PXA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">A0J61_03308</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the sorting nexin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000140">
        <property type="protein sequence ID" value="OBZ88626.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NJH1"/>
    <dbReference type="STRING" id="101091.A0A1C7NJH1"/>
    <dbReference type="InParanoid" id="A0A1C7NJH1"/>
    <dbReference type="OrthoDB" id="120967at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035091">
        <property type="term" value="F:phosphatidylinositol binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06093">
        <property type="entry name" value="PX_domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1520.10">
        <property type="entry name" value="Phox-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003114">
        <property type="entry name" value="Phox_assoc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001683">
        <property type="entry name" value="PX_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036871">
        <property type="entry name" value="PX_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013937">
        <property type="entry name" value="Sorting_nexin_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22775">
        <property type="entry name" value="SORTING NEXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22775:SF3">
        <property type="entry name" value="SORTING NEXIN-13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08628">
        <property type="entry name" value="Nexin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00787">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02194">
        <property type="entry name" value="PXA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00312">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00313">
        <property type="entry name" value="PXA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64268">
        <property type="entry name" value="PX domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50195">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51207">
        <property type="entry name" value="PXA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="31"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="domain" description="PXA" evidence="5">
        <location>
            <begin position="109"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="domain" description="PX" evidence="4">
        <location>
            <begin position="407"/>
            <end position="540"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="301"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="326"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="573"/>
            <end position="630"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="650"/>
            <end position="674"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="326"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="358"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="382"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="574"/>
            <end position="602"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="610"/>
            <end position="624"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="655"/>
            <end position="668"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51207"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OBZ88626.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="866" mass="97710" checksum="1B75D074544FE4C0" modified="2016-11-30" version="1" fragment="single">QAVSALLSLRNVFLLSDTEASSDLIRISTGVFLAVYTVLLITSGYFFLIFIALGFALGALYFNNKDGSFRIEPYERHLSYKEQTLEQASYRIELYSNSVNPPKEVQLYYQPLTAVVNQLLDYVMRDFVSSWWSKLNEYNDTTFERLARERLNTVALNVQKILLNQERNDIVMSTVYGLANTLIIHMRECRAFEESELPMTDFVVSNPQSPFSQLLSREEQHKQLRGLSQLFIKRTLPAADRESLILSTLVKELLTNFVFENVVSSISDPDFLNRQIVEFLSNKNAQNVLSSSASAIVLGTTSSSSSDEDLSSYDISPKSASHELNTVSKDTKHNTQPYQVTPPSSPERHPKPTPINTSQHPSSSLSPSSSKPETTILASLQSPPPPPSSSSPNDPPQMIFPPNSVNFTVMDISPPQANDQSINKNELVYIIQIERPAMEDQSGAEGGGYVITRTYADFESLHVILFAKHPKRMSKLQLKLPLETVTKFWMKKSTTQQKNKSVLETAGLSLQRYLDTVVQDEELGTDPLILPFLRKETRSEIAASGSVMSFSEEFQNEVASSLALIEASTTTQPSRSRSLFSRSSNSANTQNTSSSSLNVPSSFLQAPKTEANRPDDKQNTEELSGRWFTSRTAKSRQGSFSSLHSNISRDSAIVTKDEQEHADEEAHKKLSGSTHSLDLQEMEQLKVKQSETSPSITLHNKALSPMDVELLIETTYALVVEIFNLTTSNNKAWMRRSILNLLREIVRRSYTTFISEQYNDFVNQYMSPDAIVNRLNQLGEKFWPEGKWILHEKEQAKRTDEDKEKTKQLARTLMMNEMIPSTVRQLIGDQNCMTAMDRMWARIQDPDLNRVLILQVLERVTKPILG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NK58</accession>
    <name>A0A1C7NK58_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_02447</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000092">
        <property type="protein sequence ID" value="OBZ89513.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NK58"/>
    <dbReference type="STRING" id="101091.A0A1C7NK58"/>
    <dbReference type="InParanoid" id="A0A1C7NK58"/>
    <dbReference type="OrthoDB" id="10512797at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="61"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="9"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="61"/>
            <end position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ89513.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="282" mass="31403" checksum="11D2B54885DDCB7F" modified="2016-11-30" version="1">MSAEENYPEQPSGTLSSSATNPFNKQPTNRNGKKTTLSHWDRLREATSELHESNLLTVSSVASSSSSSSRNNNTTIIPPIKNKHLNPFMRSSTYEPDFRPTLANTTLVAAQAAGMTQFTRNFRPTKHQNGVAYTTSTAVQQDIYRLERDLDKLLAQLNARSQYASFAESISAFVPATTTATFNLDAAIETPKRQDATKISFIMSAILESIKKHKAATRLPLTGELLALLAAPFDHSPVLVSDCEQALDVFEYIQTRFTQIDVTEHFERLLFICRLLSSERNI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NKC4</accession>
    <name>A0A1C7NKC4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_02368</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000088">
        <property type="protein sequence ID" value="OBZ89582.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NKC4"/>
    <dbReference type="InParanoid" id="A0A1C7NKC4"/>
    <dbReference type="OrthoDB" id="10341540at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005198">
        <property type="term" value="F:structural molecule activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.70">
        <property type="entry name" value="Tobacco mosaic virus-like, coat protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001337">
        <property type="entry name" value="TMV-like_coat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036417">
        <property type="entry name" value="TMV-like_coat_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00721">
        <property type="entry name" value="TMV_coat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47195">
        <property type="entry name" value="TMV-like viral coat proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ89582.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="152" mass="17867" checksum="4B9D908DA675F4C4" modified="2016-11-30" version="1">MQYNNRGLVDSIKKAYCWHKTPELKDTIHAMEKLDYSTDREKIKNLFDQLIQGTGYEPFTSINRFPKQQSWVYIGAPEYIEVLSELKMLLNQNDMIMPGTPLPSSIITLKLNGEDRTQTFNRHLTKLKLLVASNTKVYTRETFEAEYELKWQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NKP8</accession>
    <name>A0A1C7NKP8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Arrestin domain-containing protein 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">Arrdc2</name>
        <name evidence="4" type="ORF">A0J61_04086</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the arrestin family. PalF/RIM8 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000192">
        <property type="protein sequence ID" value="OBZ87864.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NKP8"/>
    <dbReference type="STRING" id="101091.A0A1C7NKP8"/>
    <dbReference type="InParanoid" id="A0A1C7NKP8"/>
    <dbReference type="OrthoDB" id="7785529at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030674">
        <property type="term" value="F:protein-macromolecule adaptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031625">
        <property type="term" value="F:ubiquitin protein ligase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070086">
        <property type="term" value="P:ubiquitin-dependent endocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.640">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014752">
        <property type="entry name" value="Arrestin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011021">
        <property type="entry name" value="Arrestin-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011022">
        <property type="entry name" value="Arrestin_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050357">
        <property type="entry name" value="Arrestin_domain-protein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11188">
        <property type="entry name" value="ARRESTIN DOMAIN CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11188:SF161">
        <property type="entry name" value="PH-RESPONSE REGULATOR PROTEIN PALF_RIM8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02752">
        <property type="entry name" value="Arrestin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00339">
        <property type="entry name" value="Arrestin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01017">
        <property type="entry name" value="Arrestin_C"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="E set domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Arrestin C-terminal-like" evidence="3">
        <location>
            <begin position="6"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="domain" description="Arrestin C-terminal-like" evidence="3">
        <location>
            <begin position="161"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="323"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="429"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="512"/>
            <end position="541"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="323"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="437"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="512"/>
            <end position="523"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="524"/>
            <end position="541"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00037950"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM01017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OBZ87864.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="568" mass="64913" checksum="ADF1D8C7CCD67F68" modified="2016-11-30" version="1">MRNRLKSNKVIDIVLSEEKFYFPGDTIQGVVFVKPKSSIKVNSIHVKFIGTIYLQAKEKESMSLFHVRETIPMKVKVLESKEHRFPFQFSVPEKLPSAMDLNMKRMFKVDYRLEAILDRPMVPESLCPQVVYPVVILECIDITREVHAKPLEEQKLFVLPDNHKCHIKLSLPRTGYTRGETIPVNVIVNTSQSFVHKEGIAIDLVRKMETHTVKNQQKKEDILKSERLGLNIIGPYNFSQSVTTQLLIRTTPPTLQYRDILSVQYVIRIQIYDVSSKTKPVCRIELPIIIGTWPRAAVPIDEDDEDIIQYMGELMVGDEIDEDAREDDEDDDDEHWMMDPPPQGEQDFEIKKGPYLHQPIRRSGSNGSLQSNSSWIAKLDQRFSTPIPEGYLMAQNSTPYNRHSIIPPAIPSPPQPQHAIRLPTEYLNRSSSAPNLFHPPPPPPPSSNARESIHYHDPSPTPVSSMPLPHSSPRPHYIQQHRASAIPFHHRGGSDGFVAPNEVPNHTLTFIQTQPQPTQSSFITEEDSDVSSASDSEDEDDLFAIIQKKRRTEERRKRQQRQTFTTVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NL84</accession>
    <name>A0A1C7NL84_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_02067</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000073">
        <property type="protein sequence ID" value="OBZ89903.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="InParanoid" id="A0A1C7NL84"/>
    <dbReference type="OrthoDB" id="2289822at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ89903.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="168" mass="19104" checksum="294B00AF5D413845" modified="2016-11-30" version="1">MERSIGILKRTMKASHNVAANXNNILEVGALLDYLDFSGIVNFEIKKKKEDTTYKDHPQDASLSQLWAPFLASPSPISLKQANKEQVIEGGFNIRQLGYAIYQLMGRIQSTKNVVIEDNQLKYNMTIAGKLXKDDHVYYSSLHIDRCKQTNKDGYYALFQASKMCKNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NLM8</accession>
    <name>A0A1C7NLM8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Phosphatase DCR2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">DCR2</name>
        <name evidence="3" type="ORF">A0J61_02580</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000099">
        <property type="protein sequence ID" value="OBZ89366.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NLM8"/>
    <dbReference type="STRING" id="101091.A0A1C7NLM8"/>
    <dbReference type="InParanoid" id="A0A1C7NLM8"/>
    <dbReference type="OrthoDB" id="783096at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016788">
        <property type="term" value="F:hydrolase activity, acting on ester bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07383">
        <property type="entry name" value="MPP_Dcr2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.100.10.50">
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023341">
        <property type="entry name" value="MABP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32440:SF0">
        <property type="entry name" value="PHOSPHATASE DCR2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32440">
        <property type="entry name" value="PHOSPHATASE DCR2-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="Metallo-dependent phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51498">
        <property type="entry name" value="MABP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008889782" evidence="1">
        <location>
            <begin position="22"/>
            <end position="659"/>
        </location>
    </feature>
    <feature type="domain" description="MABP" evidence="2">
        <location>
            <begin position="124"/>
            <end position="277"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51498"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ89366.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="659" mass="74526" checksum="258138E6C98BBC13" modified="2016-11-30" version="1">MTRHLLSSLLFLGSLWTLSTAYITDIKLVSCDANHACANYPGYRKIPTDLNQGVQDADTVYLHYKEDKTEAPITDIQIVQGLNDSHIPHLAKWTKLKVDLNKRGEKNDDASLWLYFTKDTSISKTPVTSIIVKEGTSPLVSAEYRRIPIDLNQDIGGYHLYMYYSQDGPKDPITAITAKQCFASNCYLDVSQTHVSFLVVLIDEKGWERVEKDLNKGIVVGMSVYLFYRRSKTEDPVTDVIVLLNDQTPPEGYTKIDTNLNSIFRGDAIHVWYRTTPSNPDVLRDAVQDLAIEFGKQPVAPYGWQKINVDLNSAGNGKDSFGESTFLFVKKGYRALPKMDPLAFNQDGSFKIVQLADLHFTNEEGSCMDIPVDMECKGDLMTIEYIERLLDKEKPDLVVFTGDNIKGAGVNDARAATFKFVEPVIKRKIPWAAVFGNHDDGADLTRDELFEVMRRLPYSMVQQGPLDLPGVGNYMLNIFKSNQKQADPAFALYFLDSHGYAEDDQEGYDYIKLEQLDWLVHSSLRSSTGRLNAAAFFHIPIWEYHEESNTNRPVVKLGDARESVSSPAKNSISAFESFKKANIKFTSCGHDHVNDYCLEREDIQLCYGGGAGVGGYGAEHLDWPRRARVFELNYQGETVSTWKRLFTQEMPMIHYQTLY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NLN7</accession>
    <name>A0A1C7NLN7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_02042</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000072">
        <property type="protein sequence ID" value="OBZ89918.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NLN7"/>
    <dbReference type="InParanoid" id="A0A1C7NLN7"/>
    <dbReference type="OrthoDB" id="10587417at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ89918.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="182" mass="21015" checksum="4036CE20012EA911" modified="2016-11-30" version="1">MFGGAKNTWPLDWNGQVGYIYYLTEYEDANVILPGKSLMIPNDESELDQFEETLVALLELKNAVVIYNSQLQKEPILEEESYQNYYILNMLKRLHIVQMLNVATIRFISVSMPNQIAVNRSCTERLIFFLFDFCSSQSPDWAPEKTVKNLRSGMNNTKEFRDEFNDSIDRLVGSMCDSPTLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NLS0</accession>
    <name>A0A1C7NLS0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">NAP1-binding protein 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">NBP2</name>
        <name evidence="5" type="ORF">A0J61_01938</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000068">
        <property type="protein sequence ID" value="OBZ90005.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NLS0"/>
    <dbReference type="InParanoid" id="A0A1C7NLS0"/>
    <dbReference type="OrthoDB" id="19092at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.40">
        <property type="entry name" value="SH3 Domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036028">
        <property type="entry name" value="SH3-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001452">
        <property type="entry name" value="SH3_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00018">
        <property type="entry name" value="SH3_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00326">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50044">
        <property type="entry name" value="SH3-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50002">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0728">SH3 domain</keyword>
    <feature type="domain" description="SH3" evidence="4">
        <location>
            <begin position="208"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="24"/>
            <end position="69"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OBZ90005.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="265" mass="29395" checksum="0E1407362601517E" modified="2016-11-30" version="1">MSLNTVVAFALLLKKITRKGSLGKKNFQQRMKKSKRQTESGNLPVPSVVLESKDDHTTSTSSYSDSDFEEEDDYNFDIHDNKSSVIISPASVKSLQHSQIKAALRSSLLLVDDDTISINKSSSIFENDIQVKQKSYEGSQLEQKLGSLSLLPSSVQLAMPTLNTKQAVLGVLVRDFAYPVDSPLHYGQPATPSLENNHSTISLSSPDFTGRDARALFDFKPETEYEIALKAGQSIWVQYRQCPGWLVADVQDETGLIPESYVEFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NM74</accession>
    <name>A0A1C7NM74_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Enoyl reductase (ER) domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_01763</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000060">
        <property type="protein sequence ID" value="OBZ90175.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NM74"/>
    <dbReference type="STRING" id="101091.A0A1C7NM74"/>
    <dbReference type="InParanoid" id="A0A1C7NM74"/>
    <dbReference type="OrthoDB" id="3509362at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd08276">
        <property type="entry name" value="MDR7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="ER"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052711">
        <property type="entry name" value="Zinc_ADH-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45033">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45033:SF2">
        <property type="entry name" value="ZINC-TYPE ALCOHOL DEHYDROGENASE-LIKE PROTEIN C1773.06C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Enoyl reductase (ER)" evidence="1">
        <location>
            <begin position="22"/>
            <end position="351"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ90175.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="354" mass="37996" checksum="9174BF2423E3E2B5" modified="2016-11-30" version="1">MSQTMHSLPKTQTVYRIVEPIGLEGLKKTEEPLSSDIGNNEVLVKIKSVSLNFRDLLILNGKYSFGIKKSVVPCSDGAGEVVAVGRDVRGLQVGDRVTSNFGLDHLYGPLTNFEATLGGGTDGTLCQYKVFPQEGLNKLPKDSHLTDDEAASLVCTGATAWNALYGSGRPFIAGQSVLVLGTGGLSITTMILAKAAGAIVIVTSSSDEKLKYVKETYGADHTINYKTHPDWEKEVLKATNGEGVDIILETGGNGTIIQSLTCAKVGGQVNIIGMFTQPEKNPSLVELILGKALTVRGILVGSKQQFSELSRFVHAKKLRMPIEKVFGFSEQEVNAAFAKLESQTHIGKTIIRVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NM92</accession>
    <name>A0A1C7NM92_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">TBC domain-containing protein kinase-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">TBCK</name>
        <name evidence="4" type="ORF">A0J61_01972</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000069">
        <property type="protein sequence ID" value="OBZ89989.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NM92"/>
    <dbReference type="STRING" id="101091.A0A1C7NM92"/>
    <dbReference type="InParanoid" id="A0A1C7NM92"/>
    <dbReference type="OrthoDB" id="1668230at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004672">
        <property type="term" value="F:protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031267">
        <property type="term" value="F:small GTPase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00180">
        <property type="entry name" value="PKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00158">
        <property type="entry name" value="RHOD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.270:FF:000044">
        <property type="entry name" value="TBC Kinase homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.270">
        <property type="entry name" value="putative rabgap domain of human tbc1 domain family member 14 like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.250.10">
        <property type="entry name" value="Rhodanese-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.80">
        <property type="entry name" value="Ypt/Rab-GAP domain of gyp1p, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000195">
        <property type="entry name" value="Rab-GAP-TBC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035969">
        <property type="entry name" value="Rab-GAP_TBC_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050302">
        <property type="entry name" value="Rab_GAP_TBC_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001763">
        <property type="entry name" value="Rhodanese-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036873">
        <property type="entry name" value="Rhodanese-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47219:SF9">
        <property type="entry name" value="GTPASE ACTIVATING PROTEIN AND CENTROSOME-ASSOCIATED, ISOFORM B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47219">
        <property type="entry name" value="RAB GTPASE-ACTIVATING PROTEIN 1-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00566">
        <property type="entry name" value="RabGAP-TBC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00581">
        <property type="entry name" value="Rhodanese"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00164">
        <property type="entry name" value="TBC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52821">
        <property type="entry name" value="Rhodanese/Cell cycle control phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47923">
        <property type="entry name" value="Ypt/Rab-GAP domain of gyp1p"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50206">
        <property type="entry name" value="RHODANESE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50086">
        <property type="entry name" value="TBC_RABGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="1">
        <location>
            <begin position="1"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="domain" description="Rab-GAP TBC" evidence="2">
        <location>
            <begin position="589"/>
            <end position="774"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodanese" evidence="3">
        <location>
            <begin position="879"/>
            <end position="964"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OBZ89989.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="1001" mass="114099" checksum="FFAB04F90FEE57DA" modified="2016-11-30" version="1">MALFAQAIELKVQKDKSIPKLASVNFVGSSRVSEALAVSGHLALSAPSQIIGRFQYLKTLHHPNLCSYVEIHRGKYDRLFIVSEYHDSSLQRAKNLESSQPPPIHVSVLKQWAFEIVSALKYLDDHGIIHASLSPTNILLDKENHIQLFGYGLHYMTDGGKYVDFPLGYPIYLAPECLGQHEADGIKDDKRDIWALAIVLLEQYTRNSFWTTSDVGLIFESLWNLYEWQDEDVDIWHHPEIGSLDINQVVLQFLQNEQTDPEVEAFRQFILACLQVSVETRYGILDALSSSFFDQGLVSNHATQWVKGPILASDDIDIDALEIQTEEKADAEDVQQMLQTLPASHIYNLWKLAGGDVELDLVKRGVFLSTPIIKQLPRVCIMPDGSEIGDKVTDTAQLYSDAVYMLGYKELFQRLREGKKKVANDRFEWDTDYFKLVDENDVNFLLDDNTYDDCDSTFHESDSEGHPSTSDNDMVFLDETVTVASPQSEFINIPSPSSLRSFSNSRNSFTNMMGRSRSASSLSVNSNASIPVQQDQEQQYQEQQTNHKLPLLLREQDINYQYYRQTLFSELLRQYPASRKEIIHHAKIDIPPLLRGKVWAALLGVRGPLGHDYDQINKYVDMGSDRQIDVDVPRCHQYNQLLASSTGHEKLRRLLKAWVYENKNLVYWQGLDSLCAPFLTLHFNDEAIAFACLQKFIPKFLNNFFLSDNAPVLQEYLAVFRHLLSFHDPELSSHLDTIGFMPDLYAIPWFLTMFTHVFPLDKIYHLWDKLLVGPTSLPLFAGIAILRQIRDTLLGYEFNDCIVLFSDSFPKVDIEKCVQSALSMCKVTPPSITVRIHSPDSTTSKSKSWWEEPIPVEIKKMELAPRLNIQDVHKILAYALVLDIRSESEFVDGHIPSSINVLTTQLTSYANILKKLNRKYHLVVSQPDQGSEYTAELVRKHLARVALLQGGIEAFEAHLDSHIPLCHCRPQKQTTQGFKGKGSEPPFVMWRCKVPTPLKKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NMD0</accession>
    <name>A0A1C7NMD0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">A0J61_01686</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the protein kinase superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000056">
        <property type="protein sequence ID" value="OBZ90272.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NMD0"/>
    <dbReference type="STRING" id="101091.A0A1C7NMD0"/>
    <dbReference type="InParanoid" id="A0A1C7NMD0"/>
    <dbReference type="OrthoDB" id="68483at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035556">
        <property type="term" value="P:intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd14008">
        <property type="entry name" value="STKc_LKB1_CaMKK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000571">
        <property type="entry name" value="Maternal embryonic leucine zipper kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24346">
        <property type="entry name" value="MAP/MICROTUBULE AFFINITY-REGULATING KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24346:SF77">
        <property type="entry name" value="SERINE THREONINE PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3 4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="1 3 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="6">
        <location>
            <begin position="26"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="61"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="55"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OBZ90272.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="307" mass="35527" checksum="45C1DF5792D069A3" modified="2016-11-30" version="1">MTRWFIPASLRLRRKEPRDPLIAEKYRCLGILGQGAFGIVHLAVDIKTHQRFAMKEISKSRLERQQRYQPRPASNEQKKRRLNPTIDQFRLKEADILRNLPAHTNIIQLIEVIQDPDYSQDSIFLVMELAEKGVVMTLSEPTLYSVQQCRSIFRQLVYAVDHLHQQGIVHGDIKPHNLLLSKDNTVKLVDFGHAIHLCDIDRSFYSMSSPAFTAPEVIKKQAIKLYAATCADVWAMGVTLYCLVYGQLPFQTTNLLDLFEEIQTKDIHYPHTLDSQLLDVFSKLLEKDPTQRVTLKEIKLHPWLQTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NN20</accession>
    <name>A0A1C7NN20_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Endopolyphosphatase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">PPN1_1</name>
        <name evidence="5" type="ORF">A0J61_01408</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000044">
        <property type="protein sequence ID" value="OBZ90542.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NN20"/>
    <dbReference type="FunCoup" id="A0A1C7NN20">
        <property type="interactions" value="63"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NN20"/>
    <dbReference type="InParanoid" id="A0A1C7NN20"/>
    <dbReference type="OrthoDB" id="348678at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000324">
        <property type="term" value="C:fungal-type vacuole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000298">
        <property type="term" value="F:endopolyphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004309">
        <property type="term" value="F:exopolyphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008081">
        <property type="term" value="F:phosphoric diester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006798">
        <property type="term" value="P:polyphosphate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10340:SF55">
        <property type="entry name" value="ENDOPOLYPHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10340">
        <property type="entry name" value="SPHINGOMYELIN PHOSPHODIESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="Metallo-dependent phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008889795" evidence="3">
        <location>
            <begin position="20"/>
            <end position="488"/>
        </location>
    </feature>
    <feature type="domain" description="Calcineurin-like phosphoesterase" evidence="4">
        <location>
            <begin position="38"/>
            <end position="296"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OBZ90542.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="488" mass="57021" checksum="575D58A6C8BDA8ED" modified="2016-11-30" version="1">MKFTYISLISLLFSTGNCAVQQAPFQLPVKEVTPAHGRFLHITDIHMDQHYVYGATIQSDCHRKPKKHKHKKKEQGLLAGYWGAPGTDCDSSPRFVYHSIDWIAKEWKDKIDFVIWTGDNARHDGDPYITRTQKEITGYNQKVTKALQEAFAHPDRTIPIVPCLGNNDVHPHNQFRGMKNNPQLLTFSDIWSDFIPADQQRHFKRGGYFAVDVAQGIRVLSLNSLYFFGSNDVVNSCSDPTSPGARHVRWLKKELKRAERDQVKVIIMGHVPPTVKTFKDSCLDDYIKLSTRHADRIMGHMYGHANFDHFQIISRQFSSVSTVQQDASRFVSGLRKQYRMVKKVHDRSELVAIHVAPPLLPLFQPTFRINQYNTNQSSPQFGQWLKYTQYYSNLTYWNEQRDRWTHKPIPPVFEIEYETDKDYHLPDLTTASWLDFAERLGSKKHKKIWKMYVANLFVRTNNKWYGQSVPDSSDSYWRTIKDLFHWFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-06-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NN37</accession>
    <name>A0A1C7NN37_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_01394</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000044">
        <property type="protein sequence ID" value="OBZ90552.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NN37"/>
    <dbReference type="InParanoid" id="A0A1C7NN37"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ90552.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="62" mass="7340" checksum="A13492E700CFDE20" modified="2016-11-30" version="1">MTLDPSTQECWLLLITAVWNSLMWREKEEKNIENDELSRTKLIINYNEKQENTGLEAQVILC</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NN44</accession>
    <name>A0A1C7NN44_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_01414</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000045">
        <property type="protein sequence ID" value="OBZ90515.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NN44"/>
    <dbReference type="InParanoid" id="A0A1C7NN44"/>
    <dbReference type="OrthoDB" id="2263584at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="386"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="395"/>
            <end position="410"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ90515.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="462" mass="54782" checksum="BADCF40EDF6C692B" modified="2016-11-30" version="1">MKTRQRKQRGVLNIAELPPQHIQRSKPLRRAEILRAHLKLKQLIDQEEFGDARLLFTELIRTSRYNLHNFWKIGIQIIGRTSPNQLTDYLRAVYINAPPYLSLVTFSAYIDQLMIDKKWSKAIEEIDLLFARPQYHHPILLRKKAVCSYENWIQAKQSLPDEDETQDEYDPAVIRYERCLKIAAKNLEEAYKYYDFDVELVSFMYNFLKATEEEKAKDVVLRSLNAFENRPDFYLLKYLLEVNEDNNYFDKTQFILPLYEHNPLYDATHGLKDFVKTFCQKLANQEKKAEDQDTSERLFSLFISRIGYGITERWFLKSLVQYVLRYAISQKIYDLYRAKNLFYLLNSTYILQKTSKPDSVIRWAKKMQEAFRSYESEYVVVGSVENRDEPSNLETSTQQQSLSDKLSQSHQSDELKIETIVDDELVCKEEADDEVYKSIQYVPFLDDITLLDQYFHNPLLNI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NN86</accession>
    <name>A0A1C7NN86_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Putative 26S proteasome regulatory subunit rpn6</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">rpn6</name>
        <name evidence="4" type="ORF">A0J61_01626</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the proteasome subunit S9 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000054">
        <property type="protein sequence ID" value="OBZ90329.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NN86"/>
    <dbReference type="FunCoup" id="A0A1C7NN86">
        <property type="interactions" value="691"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NN86"/>
    <dbReference type="InParanoid" id="A0A1C7NN86"/>
    <dbReference type="OrthoDB" id="1418352at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008541">
        <property type="term" value="C:proteasome regulatory particle, lid subcomplex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034515">
        <property type="term" value="C:proteasome storage granule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005198">
        <property type="term" value="F:structural molecule activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043248">
        <property type="term" value="P:proteasome assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043161">
        <property type="term" value="P:proteasome-mediated ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.570:FF:000007">
        <property type="entry name" value="26S proteasome non-ATPase regulatory subunit 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.570">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050871">
        <property type="entry name" value="26S_Proteasome/COP9_Components"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000717">
        <property type="entry name" value="PCI_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040780">
        <property type="entry name" value="Rpn6_C_helix"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040773">
        <property type="entry name" value="Rpn6_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10678">
        <property type="entry name" value="26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 11/COP9 SIGNALOSOME COMPLEX SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01399">
        <property type="entry name" value="PCI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18503">
        <property type="entry name" value="RPN6_C_helix"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18055">
        <property type="entry name" value="RPN6_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00753">
        <property type="entry name" value="PAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00088">
        <property type="entry name" value="PINT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50250">
        <property type="entry name" value="PCI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4" id="KW-0647">Proteasome</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PCI" evidence="3">
        <location>
            <begin position="227"/>
            <end position="395"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50250"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OBZ90329.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="425" mass="48239" checksum="B66BA002EC04E4AE" modified="2016-11-30" version="1">MVIAIAKSAPSNRLEQADELKQAKNFEKAISSYQTILAEKSTSEDTLREQEYALTQLGQLYRDLHLPQELAQLIRSSRPFMLSIAKAKTAKLTRTLIDYFSDIPNCLPLQIEICKENIEWCIQEKRLFLKQALETRLVALYLDNKMYHESLNLISVLLKELKRLDDKMVLVEVQLLESRVCHALRNLPKARAALTSARTSANSIYCPPLLQAALDMQSGVLHAEEKDYKTAYSYFFETFEGYSSQEDPKAILALKYMLLCKIMLNLTEDVHSIIGGKVALRYAGVEIDAMKAVANAHKNRNLQEFETALATYTNELNNDPIIRAQLAALYDTLLEQNLVRIIEPFSRVEISHIADMVKLPTQQVEAKLSQMILDKKFHGILDQGAGCLIVFDEPEQDKTYEMAIETLKQVDKVVSSLYQKAAELS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-06-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NNF3</accession>
    <name>A0A1C7NNF3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_01265</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000038">
        <property type="protein sequence ID" value="OBZ90673.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NNF3"/>
    <dbReference type="InParanoid" id="A0A1C7NNF3"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ90673.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="96" mass="11124" checksum="1C83E4189B438B7E" modified="2016-11-30" version="1">MFTAYVSRCSEESQGLNEPNIDTVNATAQIDCQATKMSNDRRMFFNERIVYNIHCLVESAIMYNAIEIRWDYFVSHIESPYGHVQIQTQPQVTISI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-06-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NNI4</accession>
    <name>A0A1C7NNI4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_01289</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000039">
        <property type="protein sequence ID" value="OBZ90647.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NNI4"/>
    <dbReference type="InParanoid" id="A0A1C7NNI4"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ90647.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="380" mass="44450" checksum="EE6DB2B5DD550AF7" modified="2016-11-30" version="1">MTSNEKTLLSDSLLVENLRELYLESIKGPIYEIDKGIKPEEKINFPLYVLSDADKNEPTKIASWLGYLIQYMYNDNRDYDLSEVGTLVLSILELLVPKCGVQLVNRLENYVVELVVLTDAHWNFINNNVPFQPNSDDLTKYQEMEDHSSDKKRTYDIAIYRLFRHLKSMVHFELNTAYTVRDYTIAFSSLILALGKEPTSHNVASFGDPRVNFKLQPTLTALRKVHFFFTAYSNLRIELSQELISWCSHPAPSEAIEIVGPKIKIWDGIGLTHVTIISDMLRDCRPYFDRYPHFKCEIGYFDYGLEELNKKIEIYDKYYKVIFGDRAREILSKKVPELLKLAKVYASRKNPRFKRYAPQLGYSVFEQSFRQYLRNKSQHE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NPB9</accession>
    <name>A0A1C7NPB9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Transportin-1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">Tnpo1_0</name>
        <name evidence="11" type="ORF">A0J61_01097</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the importin beta family. Importin beta-2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000031">
        <property type="protein sequence ID" value="OBZ90848.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NPB9"/>
    <dbReference type="FunCoup" id="A0A1C7NPB9">
        <property type="interactions" value="1137"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NPB9"/>
    <dbReference type="InParanoid" id="A0A1C7NPB9"/>
    <dbReference type="OrthoDB" id="951172at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031981">
        <property type="term" value="C:nuclear lumen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031267">
        <property type="term" value="F:small GTPase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006606">
        <property type="term" value="P:protein import into nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.10.10:FF:000028">
        <property type="entry name" value="Transportin-1 isoform 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058584">
        <property type="entry name" value="IMB1_TNPO1-like_TPR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001494">
        <property type="entry name" value="Importin-beta_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040122">
        <property type="entry name" value="Importin_beta"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057672">
        <property type="entry name" value="TPR_IPO4/5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10527">
        <property type="entry name" value="IMPORTIN BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13513">
        <property type="entry name" value="HEAT_EZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03810">
        <property type="entry name" value="IBN_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25574">
        <property type="entry name" value="TPR_IMB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25780">
        <property type="entry name" value="TPR_IPO5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00913">
        <property type="entry name" value="IBN_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50166">
        <property type="entry name" value="IMPORTIN_B_NT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Importin N-terminal" evidence="10">
        <location>
            <begin position="44"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="354"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="355"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="376"/>
            <end position="392"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00038423"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50166"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="OBZ90848.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="941" mass="106359" checksum="E913182DDD7DD39A" modified="2016-11-30" version="1">MCDKRNSNFEMITVMSAWQPSAQGLSDLLQLLREAINPTDSQNVQERLEYFNKIPDYNNYLAYILTQMPQEDQYIRSVAGLTLKNNIRSYFPTIQPQVLDYIKECCIQHIGDPGVGKSISFVISSIVSRGSIQQWPQILQVLLEKLEDPNPVMVENAFSAFQKICEDSSRDLDSAINGVQPLEYMIPKFIAFFDHPDPKVRLSAISCTSQFINLRSEPLMSRINDFLSSLFNRATDDNVDVRKVVCQSLVSLLETCPNVLLPHMPNLVEYMLFCTQSDDSDLALEACEFWLVFAEQDELRDQLRPYLQKVVPVLLKGMVYSEIDLMTLGGDEDDAHIADDEQDIKPRFHRATVVENEHTNKEEEASDKKKAAGLLDENESDGDDDDDDDDYDEFEEDEFYGEWNLRKCSAATLDVLCTSFETEVIHILIPLLKGELESSDWLHRECGILALGAAAEGGMQEIAPHLPELVPYLLNNLNDPKQTQPNNILNVYQPLVRSITCWTLGRYCAWIVQSARQSHEARQHYFEPLVQILLQRILDNNKRVQEAACSSFSLLEEEAGADLVPYLQPILTTLCSAFAKYQHRNLLLLYDTVGTLADVVGEVLNNPQYIEVIMPPLINKWQEVSDDSTDLFPLLECLSSVTTALGKGFKPFAEPVYRRCVVLVCKTLEECRLCTMNPSMEEPDKDFMIVALDLLSGIVQALNTDAEPLVASTNPPVVQLLSLCIQDEVAEVRQSTYALLGDLAISCFEHIRAVVPQFMPLLLQQIDPQAEHLSVCNNATWAAGEIALKWGNEITDYVDHLLQRLFPLMANPQIQRTLLENVAITIGRLGLVCPNKVAPHLELFIQPWLMALTPIRDNEEKSSAFSGLCEMIKVNPQGAVKEFPAFCTAIVNYQNLPPALHESFANILMGYKNMFGESQWEQGFLSMPQEVSIPLRERYHI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NPM4</accession>
    <name>A0A1C7NPM4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Xylanolytic transcriptional activator regulatory domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">A0J61_00984</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000026">
        <property type="protein sequence ID" value="OBZ90968.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NPM4"/>
    <dbReference type="STRING" id="101091.A0A1C7NPM4"/>
    <dbReference type="InParanoid" id="A0A1C7NPM4"/>
    <dbReference type="OrthoDB" id="2123952at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050815">
        <property type="entry name" value="TF_fung"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47338:SF5">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47338">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Xylanolytic transcriptional activator regulatory" evidence="7">
        <location>
            <begin position="235"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="14"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="581"/>
            <end position="600"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="31"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="49"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="91"/>
            <end position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OBZ90968.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="700" mass="79072" checksum="145579A297AFAE0C" modified="2016-11-30" version="1">MLEQRLAKMEKILLSADKQNTADPLTEEYDQNQSSEQDNNSVGDHHLVSPNPLGSLPYPSSSSNNETLFSLKTPMVGTKRPSEDLSEAVASPKSFSSMTSSSLPSPQSHMLHASPVSREAKYDTLPSPAIIDHCIDLFFEYLYSSMPIFDKETIKSQITQRKRSDFFIFCFLAATARFSNAPDVAKNPPWSAGEKYADKARPLIIKVLDEPSISNTQALLLLAMHEYGCGRGPRSGMYNGMAMRMAMELGLHEELEDSEECCDSEMSKSWSQEYRRRLLWVLYSTDKISSAATGKPPSLSHVYCNVFLPSSDNFKMDQYYAENLDGSRYVMNNRSGLQDSQLLSASDAPTNEDNSLSRRSPLSAFAYFVRIIDLLGRVSTYVNSKRRDSSNFIPPCNPDSDFQQLDRAIDTWYDELPMHLKNTPTNLELSRSSSETNESRLFTIIHIAHNTLIVLLHRPSLVASDTLYSHLIQPSIKQFISNSVEKCTAAVDNVTMLLKEVSQRKECATPFMSYFVYTVATVVVSNSFSPRKEEAQKAKQALGVYFQFLLNARGLWAMADKLYFMIRDLYTIHSNILKQQQQQQQQQQRSKEMPAENASPLSSVRSSQQSLLQPFQSQESFSYPMQTLPLQQQQQQQQQAIDQLSSVNNSLADWTLPYYMNALAVPTTNSLENGDAFSLFQIPQAFNEPFLYNNNNNNSM</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NPP0</accession>
    <name>A0A1C7NPP0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="10">ADP-ribosylation factor-binding protein GGA2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">GGA2</name>
        <name evidence="10" type="ORF">A0J61_00892</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">May play a role in the regulation of membrane traffic through the trans-Golgi network.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Golgi apparatus</location>
            <location evidence="1">trans-Golgi network</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000023">
        <property type="protein sequence ID" value="OBZ91082.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NPP0"/>
    <dbReference type="FunCoup" id="A0A1C7NPP0">
        <property type="interactions" value="168"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NPP0"/>
    <dbReference type="InParanoid" id="A0A1C7NPP0"/>
    <dbReference type="OrthoDB" id="2018246at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005802">
        <property type="term" value="C:trans-Golgi network"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035091">
        <property type="term" value="F:phosphatidylinositol binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043130">
        <property type="term" value="F:ubiquitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006895">
        <property type="term" value="P:Golgi to endosome transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006896">
        <property type="term" value="P:Golgi to vacuole transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043328">
        <property type="term" value="P:protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd16998">
        <property type="entry name" value="VHS_GGA_fungi"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.90:FF:000008">
        <property type="entry name" value="VHS domain protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.5.170:FF:000024">
        <property type="entry name" value="VHS domain-containing protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.170">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.160">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1230">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052653">
        <property type="entry name" value="ARF-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008152">
        <property type="entry name" value="Clathrin_a/b/g-adaptin_app_Ig"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013041">
        <property type="entry name" value="Clathrin_app_Ig-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008942">
        <property type="entry name" value="ENTH_VHS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008153">
        <property type="entry name" value="GAE_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004152">
        <property type="entry name" value="GAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038425">
        <property type="entry name" value="GAT_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002014">
        <property type="entry name" value="VHS_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47180">
        <property type="entry name" value="ADP-RIBOSYLATION FACTOR-BINDING PROTEIN GGA1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47180:SF1">
        <property type="entry name" value="ADP-RIBOSYLATION FACTOR-BINDING PROTEIN GGA1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02883">
        <property type="entry name" value="Alpha_adaptinC2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03127">
        <property type="entry name" value="GAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00790">
        <property type="entry name" value="VHS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00809">
        <property type="entry name" value="Alpha_adaptinC2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00288">
        <property type="entry name" value="VHS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49348">
        <property type="entry name" value="Clathrin adaptor appendage domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48464">
        <property type="entry name" value="ENTH/VHS domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89009">
        <property type="entry name" value="GAT-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50180">
        <property type="entry name" value="GAE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50909">
        <property type="entry name" value="GAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50179">
        <property type="entry name" value="VHS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="3" id="KW-0653">Protein transport</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="domain" description="VHS" evidence="7">
        <location>
            <begin position="39"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="domain" description="GAT" evidence="9">
        <location>
            <begin position="202"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="domain" description="GAE" evidence="8">
        <location>
            <begin position="449"/>
            <end position="559"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="358"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="421"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="365"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="425"/>
            <end position="440"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004601"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00053552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50909"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OBZ91082.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="559" mass="62630" checksum="08578D8DDBBADF7C" modified="2016-11-30" version="1">MNFFEAQVHSMPSTLVTIIGKLYISRVVDKQNNIFIEGACSPARFEPELSLNLEICEMINKKQGSAPREAAFTIVKLINSKNINQAMLALTLLDNCVKNCGYPFHLQIATKEFLNELVRKFPERPAPFPNPVIQRILYLIKEWKVALTEISKHKDDLVHIKDMYRLLRFKGYRFPDLRDASVAALAPSDSLKSAHELEEEDRIAQSAKLQELIRRGRPQDLVEANRLMKIMSGFDTRQTPDYGQKFEDELAKIQDKTILLYEMLETVKPGERVDRNETIMDLKSACASAQPKIQKMITEEEDNDKIENLLILNDMINNAMAKFADIRKGLFDTHYEISGKPPTATSTEEAPRQAISLIDLDDSVDNTTTTPPPAQSTINDLSDIFGTNLTVSNTSSPAPSTQKTPDIFDLLGGASQPSAQYNTHISPPSSSFSSPIISSPSLPPPVQQGSTRTITLVNKNGLLIELEVKEQGSQCLMKAFYSNQSTAPMDQLMLRLAAPKSMQIKLEPQSSQALPPKSSRSITQIIALTNPQKEPLRLRYKITYEQFGVEMEIAGDYHD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NPV4</accession>
    <name>A0A1C7NPV4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_01003</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000027">
        <property type="protein sequence ID" value="OBZ90939.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NPV4"/>
    <dbReference type="STRING" id="101091.A0A1C7NPV4"/>
    <dbReference type="InParanoid" id="A0A1C7NPV4"/>
    <dbReference type="OrthoDB" id="2291000at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="61"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="118"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="428"/>
            <end position="488"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="61"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="120"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="132"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="169"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="181"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="428"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="457"/>
            <end position="466"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ90939.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="488" mass="54224" checksum="1174E26845E20BFB" modified="2016-11-30" version="1">MFTAFGGIKKREPLFTFKRKAAFSPALNDVSTQINNLSYTPSSTVNTSIRFSSTASIVARKSNSLQKSPAPQAQKKPVVVEKEQEDTAIFDFPDKLEKNALEIKLMVAERRAVPDTKIPLVRKKSKSKSIKSNKMSPSPSCSSSSSTATTNSSPSNSPTVQKKSPSSNLKRKPSAKKQAKTALTNNNITPTNANVPMPAVSRPLANTCDESFDIFAFDPQPTSHLSHRRTVHKTTSHSRNQINAVEQQHTILPKPPTVPSHASTCNSEMDIDHLLNQPLNFDAMANLLSPSHFGDNSNFSDSYSYTSMPLSTTHYPITSFNNHTNYTTNTPLYGITQSTPSPNNGYQTTCATSTNACTYQTDVHNRPAEKKRKPNLVAHLKSANGEKEKKQIAQDFNFLFSDEDEEESEEAITSILPIREIINHAREKSPSPELSYEQKMERELEAMMQSEFGLKDSSTLSESEASSRPRYQPQNKVNVRVTFQKKKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NQW1</accession>
    <name>A0A1C7NQW1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Guanine nucleotide exchange factor for Rab-3A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">Rab3il1</name>
        <name evidence="5" type="ORF">A0J61_00534</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000012">
        <property type="protein sequence ID" value="OBZ91418.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NQW1"/>
    <dbReference type="FunCoup" id="A0A1C7NQW1">
        <property type="interactions" value="7"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NQW1"/>
    <dbReference type="InParanoid" id="A0A1C7NQW1"/>
    <dbReference type="OrthoDB" id="5560525at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051286">
        <property type="term" value="C:cell tip"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070319">
        <property type="term" value="C:Golgi to plasma membrane transport vesicle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005085">
        <property type="term" value="F:guanyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006887">
        <property type="term" value="P:exocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd21044">
        <property type="entry name" value="Rab11BD_RAB3IP_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.910">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040351">
        <property type="entry name" value="RAB3IL/RAB3IP/Sec2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009449">
        <property type="entry name" value="Sec2_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14430">
        <property type="entry name" value="RABIN3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14430:SF0">
        <property type="entry name" value="SEC2P DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25555">
        <property type="entry name" value="RAB3A-like_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06428">
        <property type="entry name" value="Sec2p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144284">
        <property type="entry name" value="Sec2 N-terminal region"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GDP/GTP exchange factor Sec2 N-terminal" evidence="4">
        <location>
            <begin position="20"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="160"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="398"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="12"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="161"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="398"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="437"/>
            <end position="450"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF06428"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OBZ91418.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="450" mass="51555" checksum="D96A6F54DFDAF94D" modified="2016-11-30" version="1">MSCQHCESDKTILSLQHELDQKNIQLERLEQDMHTLNQKYVAEIERVGNIQHEKDMVEHELEELSLKLFEEANAMVAVEKKARWQIENELRQTQEQLLAEQAQLRELRLRLTSDRPSDATSILDSSTTIIMKSRLKDQIDLDGLKRVSANHIMKYTRKEQLTQQRTISMPPTPSTSDHINAKNKRPSTIDGFQLESFREYTIASSQKLLTPKKLNQTTFMKHCLSEDIEPCLRFGPQSKLSIKKMIDFLSRQACFIEHIHTGLAPSSSVVQPSKPLWERFNANTPTKSIVVSNSCSACGRSADAVVLNYRFRLDETDNWLPIDQYCRDRLVAVCEFFVFIRNIQMNLYQDRSIEDLYTENIRLRLQMFYSRMGALPVVMDDLGLDHTNQAINTQPVVLEEEGDVAGETTDGLDDDLDLLPDDASSLHSITHPHTPEPYNSTSTPSTTMKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NQZ7</accession>
    <name>A0A1C7NQZ7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">LysM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">A0J61_00400</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000009">
        <property type="protein sequence ID" value="OBZ91547.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NQZ7"/>
    <dbReference type="STRING" id="101091.A0A1C7NQZ7"/>
    <dbReference type="InParanoid" id="A0A1C7NQZ7"/>
    <dbReference type="OrthoDB" id="3044029at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008061">
        <property type="term" value="F:chitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00118">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.350.10">
        <property type="entry name" value="LysM domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018392">
        <property type="entry name" value="LysM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052210">
        <property type="entry name" value="LysM1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036779">
        <property type="entry name" value="LysM_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34997">
        <property type="entry name" value="AM15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34997:SF1">
        <property type="entry name" value="PEPTIDOGLYCAN-BINDING LYSIN DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01476">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00257">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54106">
        <property type="entry name" value="LysM domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51782">
        <property type="entry name" value="LYSM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0147">Chitin-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0843">Virulence</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008889841" description="LysM domain-containing protein" evidence="4">
        <location>
            <begin position="20"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="domain" description="LysM" evidence="5">
        <location>
            <begin position="34"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="194"/>
            <end position="223"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022669"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OBZ91547.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="378" mass="38302" checksum="66FBA3BCCB30165A" modified="2016-11-30" version="1">MHFTTLACAALAVMSTASAASLRTMKTYTVSCDKTYTVVNGDTCSVIAQEYGILTSQLKKWNPSINSKCSNLYIDQILCLSDPTTSSSTVPVSSTCTAGSYGLAEGNGYAGYCCKSQADCLDDCIKGVCNGPKAPSSGSGSSGSGSSGSSGSSGKCVAGVAGLGKGNGYAGYCCKNQADCLDDCVKGACVGPKAPSSGSGSGSGDSDDGSGSGSGSGTSSTGKVVQISSSKDFCLFLPSSPGNKAENGGKIDTDAIADSEKSAVAFCTKPNVNAPNAGLFPEGFITSAKYQTKADEGFVQIRGKIDISKYSLSPKDEGGQYDNHGAGSPPNSSCAGYRYYVALVEPSSGDFCIRCCSTYANCNAGRSEYGCNRVVPEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NR14</accession>
    <name>A0A1C7NR14_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 14 17">Homoserine dehydrogenase</fullName>
            <shortName evidence="14">HDH</shortName>
            <ecNumber evidence="5 14 17">1.1.1.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="21" type="primary">SPBC776.03</name>
        <name evidence="21" type="ORF">A0J61_01099</name>
    </gene>
    <organism evidence="21 22">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="21 22" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="21 22">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">Catalyzes the conversion of L-aspartate-beta-semialdehyde (L-Asa) to L-homoserine (L-Hse), the third step in the biosynthesis of amino acids that derive from aspartate (the aspartate family of amino acids), including methioinine and threonine, the latter of which is a precursor to isoleucine; production of homoserine leads to a branch-point in the pathway as it can either be O-phosphorylated for processing to threonine, or O-acylated for processing to methionine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>L-homoserine + NADP(+) = L-aspartate 4-semialdehyde + NADPH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:15761"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57476"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:537519"/>
            <dbReference type="EC" id="1.1.1.3"/>
        </reaction>
        <physiologicalReaction direction="right-to-left" evidence="12">
            <dbReference type="Rhea" id="RHEA:15763"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>a metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:25213"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3 17">Amino-acid biosynthesis; L-methionine biosynthesis via de novo pathway; L-homoserine from L-aspartate: step 3/3.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 17">Amino-acid biosynthesis; L-threonine biosynthesis; L-threonine from L-aspartate: step 3/5.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 14 18">Belongs to the homoserine dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="21">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.3" evidence="5 14 17"/>
    <dbReference type="EMBL" id="LUGH01000031">
        <property type="protein sequence ID" value="OBZ90856.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NR14"/>
    <dbReference type="FunCoup" id="A0A1C7NR14">
        <property type="interactions" value="150"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NR14"/>
    <dbReference type="InParanoid" id="A0A1C7NR14"/>
    <dbReference type="OrthoDB" id="67851at2759"/>
    <dbReference type="UniPathway" id="UPA00050">
        <property type="reaction ID" value="UER00063"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00051">
        <property type="reaction ID" value="UER00465"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004412">
        <property type="term" value="F:homoserine dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070403">
        <property type="term" value="F:NAD+ binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009090">
        <property type="term" value="P:homoserine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009086">
        <property type="term" value="P:methionine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009088">
        <property type="term" value="P:threonine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.360.10:FF:000006">
        <property type="entry name" value="Bifunctional aspartokinase/homoserine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.360.10">
        <property type="entry name" value="Dihydrodipicolinate Reductase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005106">
        <property type="entry name" value="Asp/hSer_DH_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011147">
        <property type="entry name" value="Bifunc_Aspkin/hSer_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001342">
        <property type="entry name" value="HDH_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019811">
        <property type="entry name" value="HDH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022697">
        <property type="entry name" value="HDH_short"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43070">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43070:SF5">
        <property type="entry name" value="HOMOSERINE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00742">
        <property type="entry name" value="Homoserine_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03447">
        <property type="entry name" value="NAD_binding_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036497">
        <property type="entry name" value="HDH_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55347">
        <property type="entry name" value="Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01042">
        <property type="entry name" value="HOMOSER_DHGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 14 17" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="11 14 17" id="KW-0486">Methionine biosynthesis</keyword>
    <keyword evidence="9 14 16" id="KW-0521">NADP</keyword>
    <keyword evidence="10 14 17" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="22" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 14 17" id="KW-0791">Threonine biosynthesis</keyword>
    <feature type="domain" description="Aspartate/homoserine dehydrogenase NAD-binding" evidence="20">
        <location>
            <begin position="8"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="domain" description="Homoserine dehydrogenase catalytic" evidence="19">
        <location>
            <begin position="157"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="15">
        <location>
            <position position="231"/>
        </location>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <begin position="8"/>
            <end position="13"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="91"/>
        </location>
        <ligand>
            <name>NADPH</name>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="115"/>
        </location>
        <ligand>
            <name>NADPH</name>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="216"/>
        </location>
        <ligand>
            <name>L-homoserine</name>
            <dbReference type="ChEBI" id="CHEBI:57476"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001920"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005062"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00006753"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00013213"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00013376"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00048841"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00059589"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PIRNR" id="PIRNR036497"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PIRSR" id="PIRSR036497-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PIRSR" id="PIRSR036497-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="RuleBase" id="RU000579"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="RuleBase" id="RU004171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="Pfam" id="PF00742"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="Pfam" id="PF03447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="EMBL" id="OBZ90856.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="369" mass="39809" checksum="132F9C248EC0BCF5" modified="2016-11-30" version="1">MVNIGIVGVGLVGSELVSQIAKSSRSHLFKVVGLTTSQKMVLSDASYSALSITQEANLRSTVNATGIQTDLQQFADYLSNAKEHSIIIDCTASEQVAHLYPSWLRSGLSVVTPNKKGFSSSLDLYKEIQSLAVNTNMKLGKKSPLVYHEATVGAGLPVLSTLSDLLKTGDEIEKIEGIFSGTLSYLFNNFSSLSQTGETKSFSEIVRVAKDLGYTEPDPRDDLNGMDVGRKVTICGRLAGLELDLSTLPVENIVPEALQAVQSTEEFMTRLPEFDQHFADLNAAALKENQVLRYVGLVDIKGGQSGVKLIKYPASHPFASLQGSDNIIKFTTKYFPSGIIIQGSGAGAAVTAYGIFTDLLRIQERVQCC</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NR65</accession>
    <name>A0A1C7NR65_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Putative membrane protein C6F6.13c</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">A0J61_00510</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TMCO4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000011">
        <property type="protein sequence ID" value="OBZ91460.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NR65"/>
    <dbReference type="FunCoup" id="A0A1C7NR65">
        <property type="interactions" value="3"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NR65"/>
    <dbReference type="InParanoid" id="A0A1C7NR65"/>
    <dbReference type="OrthoDB" id="277931at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007941">
        <property type="entry name" value="DUF726"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17920:SF3">
        <property type="entry name" value="TRANSMEMBRANE AND COILED-COIL DOMAIN-CONTAINING PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17920">
        <property type="entry name" value="TRANSMEMBRANE AND COILED-COIL DOMAIN-CONTAINING PROTEIN 4 TMCO4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05277">
        <property type="entry name" value="DUF726"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="359"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="403"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="113"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="708"/>
            <end position="813"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="880"/>
            <end position="916"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="18"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="123"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="718"/>
            <end position="732"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="736"/>
            <end position="759"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="774"/>
            <end position="799"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="803"/>
            <end position="813"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="880"/>
            <end position="902"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OBZ91460.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="983" mass="107297" checksum="81CB76CA5A8B878E" modified="2016-11-30" version="1">MSVKNKSESIVDEGDCNSMCSSRSKPNSSSIPAEDASRKDVSDKFLASVSQDNIHNQPLTAELLAEQNELYSNKLEPKPNAIRAWAADLPEVPDSVQPILTSTHIFEMEDLTLDDETDPDHPSNNNHSAQPRIQETKDVFTETQKVAYVGLCYLTSLEVVHDFEGKDFTDARMSASNWQRKIMRMLYVHMDISPDEIKMIESLSKHNILPTDLVHQFTSQGETTEVQLDDLNTKPTTDEERKALETERSEPNKIIIDLCWTVMCDLFLICLSTETYDARSRVFVARITSYLSLDWFQVIGFEKRIAEHLLQDAAWETETVTSVSTTMTSMTSANVDSNGMIKNELERTSRNKQRKKKRYVMIGLATIGGGLILGLSAGVMAPVIAGGLGAILTTVGVTGTTGFLGGTAGIALITGGATVAGGRLGGKSMNKRMKSIDVFEFLPIHVDENVNCIVTITGWLPSKEQEESSLPFSTIDHIMGDHYNLYWEPEMLEELGSAFRILATEAVTFSIQQALAHTIMGALLAGLAWPLALTKLGYIVDNPWANALDRSRIAGLVLADSLMNRNLGTRPITLVGYSLGARVIFFCLLELARVNAFGLIENVFLFGTPVSGSKAEWKQCTSVVSGRFVNGYATNDWLLGFLFRTSTGGLGNIAGLRPLSHIEGNRVHNVDCTDLITGHLSYRASMPKLLKRAGFVVTSEEIPIREKEKNRFSLSPEEDGKNSTDIKNKHLDSATSSITKRNSLSSLSSGKASIQISSKATSPGPVNDEVECNYQGNDDTPARTASSSTVPLTVGSQTPPCEPNEKRKSERPMSDIDIIADIIANAAAAASSKSGTYSSLSSGKASIAPISNTLSDHTVTTTVSQSTVVGQRTKRRSTLSFFGSKSETTSSSSLTQNNTTSFDSSSVLDKNKPNSRSSLLFSPPSFFAIKKKVETEEEKELKDAGIVVKEIKTTLGKLIVPPEVVNPMPQIKLEAPQFARLNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NS49</accession>
    <name>A0A1C7NS49_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Nuclear distribution protein PAC1</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">Lissencephaly-1 homolog</fullName>
            <shortName evidence="11">LIS-1</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11">nudF homolog</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="primary">PAC1_0</name>
        <name evidence="11" type="synonym">LIS1</name>
        <name evidence="11" type="synonym">PAC1</name>
        <name evidence="14" type="ORF">A0J61_00122</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for nuclear migration during vegetative growth as well as development. Required for retrograde early endosome (EE) transport from the hyphal tip. Required for localization of dynein to the mitotic spindle poles. Recruits additional proteins to the dynein complex at SPBs.</text>
    </comment>
    <comment type="subunit">
        <text evidence="11">Self-associates. Interacts with NDL1 and dynein.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="11">Cytoplasm</location>
            <location evidence="11">Cytoskeleton</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="11">Cytoplasm</location>
            <location evidence="11">Cytoskeleton</location>
            <location evidence="11">Spindle pole</location>
        </subcellularLocation>
        <text evidence="11">Localizes to the plus ends of microtubules at the hyphal tip and the mitotic spindle poles.</text>
    </comment>
    <comment type="domain">
        <text evidence="11">Dimerization mediated by the LisH domain may be required to activate dynein.</text>
    </comment>
    <comment type="similarity">
        <text evidence="11">Belongs to the WD repeat LIS1/nudF family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000002">
        <property type="protein sequence ID" value="OBZ91838.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NS49"/>
    <dbReference type="STRING" id="101091.A0A1C7NS49"/>
    <dbReference type="InParanoid" id="A0A1C7NS49"/>
    <dbReference type="OrthoDB" id="10264588at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005875">
        <property type="term" value="C:microtubule associated complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000922">
        <property type="term" value="C:spindle pole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070840">
        <property type="term" value="F:dynein complex binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007154">
        <property type="term" value="P:cell communication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000132">
        <property type="term" value="P:establishment of mitotic spindle orientation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051012">
        <property type="term" value="P:microtubule sliding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0023052">
        <property type="term" value="P:signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.10:FF:000342">
        <property type="entry name" value="Nuclear distribution protein PAC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.960.30:FF:000002">
        <property type="entry name" value="Platelet-activating factor acetylhydrolase ib"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.960.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03141">
        <property type="entry name" value="lis1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017252">
        <property type="entry name" value="Dynein_regulator_LIS1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037190">
        <property type="entry name" value="LIS1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006594">
        <property type="entry name" value="LisH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056795">
        <property type="entry name" value="PAC1-like_LisH-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19848:SF8">
        <property type="entry name" value="F-BOX AND WD REPEAT DOMAIN CONTAINING 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19848">
        <property type="entry name" value="WD40 REPEAT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24951">
        <property type="entry name" value="LisH_PAC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037647">
        <property type="entry name" value="Dynein_regulator_Lis1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00667">
        <property type="entry name" value="LisH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109925">
        <property type="entry name" value="Lissencephaly-1 protein (Lis-1, PAF-AH alpha) N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50896">
        <property type="entry name" value="LISH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="6"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 11" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="4 11" id="KW-0132">Cell division</keyword>
    <keyword evidence="8 11" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2 11" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9 11" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="5 11" id="KW-0493">Microtubule</keyword>
    <keyword evidence="7 11" id="KW-0498">Mitosis</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 11" id="KW-0813">Transport</keyword>
    <keyword evidence="3 12" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="PAC1-like LisH-like dimerisation" evidence="13">
        <location>
            <begin position="7"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="12">
        <location>
            <begin position="106"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="12">
        <location>
            <begin position="148"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="12">
        <location>
            <begin position="191"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="12">
        <location>
            <begin position="233"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="12">
        <location>
            <begin position="312"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="12">
        <location>
            <begin position="337"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="12">
        <location>
            <begin position="379"/>
            <end position="413"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF24951"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="OBZ91838.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="413" mass="46744" checksum="3C4E5F0F0449A78C" modified="2016-11-30" version="1">MTSILSDRQKDELHKAILDYLSTNGFTESFNTLKSETHNEDFTADPKQKYAGLLEKKWTSVIRLQKKIMELETKSAQMQEEINNAPVRKQTSSVDWIPRAPERQSMTGHRSPVTRIAFHPVYQTLASSSEDTTLKIWDYETGEFERTLKGHTKSVQDVGFDPKGNFLVSCSADLSIKVWDINNDYKCIKTLYGHDHSVSSVGYMPSGDVIISASRDKTIKLWDASSGYCIKTLAGHLDWVRTVKPSEDGRYLVSASNDQTARLWDVQSGEAKMEFRGHEHVVECAIFVPINAYPYIQELIGDENKQKDPMAGQYIITASRDKTIKLWNSNGQLLHTLIGHDNWVRGLVVHPNGKYLLSASDDKTIKIWDLKTGRCQKTIDAHSHFVTCIAYCHISPVVATGSVDQTIKLWQCR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NS65</accession>
    <name>A0A1C7NS65_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_00151</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000003">
        <property type="protein sequence ID" value="OBZ91799.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NS65"/>
    <dbReference type="STRING" id="101091.A0A1C7NS65"/>
    <dbReference type="InParanoid" id="A0A1C7NS65"/>
    <dbReference type="OrthoDB" id="2291051at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="210"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="155"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="170"/>
            <end position="185"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ91799.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="263" mass="27898" checksum="647C0E9F353B8E0B" modified="2016-11-30" version="1">MSSTSTTYYASATTTNSSSSSNNNGQSLGQSSNDQQYNQNQNVNTNNQNVNNQYNNNQNQNNNQNTSPYNNGSNNNSNMNNGSNTNTNNQSYNNGNTSNNYPSGNTLPNGGNSNLGNSAGYGNNANTNTIPNNAVINNNNNGNSYNNGNSAPYNTNGNSNINTSPGTNVNSYNTPNGSNGYSNGNIGYNANSNGSSFPNSSNDPNGTKTIIIIVCVVVGVVLMAGSGLLVFLKRRREKKKENMANAFFEFSVDKSSDFKTPAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NSD1</accession>
    <name>A0A1C7NSD1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Ubiquitin thioesterase OTU</fullName>
            <ecNumber evidence="9">3.4.19.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">yod1</name>
        <name evidence="11" type="ORF">A0J61_00587</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Hydrolase that can remove conjugated ubiquitin from proteins and may therefore play an important regulatory role at the level of protein turnover by preventing degradation.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 9">
            <text>Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).</text>
            <dbReference type="EC" id="3.4.19.12"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.19.12" evidence="9"/>
    <dbReference type="EMBL" id="LUGH01000013">
        <property type="protein sequence ID" value="OBZ91386.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NSD1"/>
    <dbReference type="FunCoup" id="A0A1C7NSD1">
        <property type="interactions" value="256"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NSD1"/>
    <dbReference type="InParanoid" id="A0A1C7NSD1"/>
    <dbReference type="OrthoDB" id="65596at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004843">
        <property type="term" value="F:cysteine-type deubiquitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030968">
        <property type="term" value="P:endoplasmic reticulum unfolded protein response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036503">
        <property type="term" value="P:ERAD pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016579">
        <property type="term" value="P:protein deubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd22745">
        <property type="entry name" value="OTU_OTU1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.70.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048857">
        <property type="entry name" value="OTU1_Ubl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003323">
        <property type="entry name" value="OTU_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057766">
        <property type="entry name" value="Znf-C2H2_OTU1-like_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13312">
        <property type="entry name" value="HIV-INDUCED PROTEIN-7-LIKE PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13312:SF0">
        <property type="entry name" value="UBIQUITIN THIOESTERASE OTU1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02338">
        <property type="entry name" value="OTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21403">
        <property type="entry name" value="OTU1_UBXL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24560">
        <property type="entry name" value="zf-C2H2_OTU1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50802">
        <property type="entry name" value="OTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 9" id="KW-0788">Thiol protease</keyword>
    <keyword evidence="5 9" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="8" id="KW-0862">Zinc</keyword>
    <keyword evidence="4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="OTU" evidence="10">
        <location>
            <begin position="96"/>
            <end position="211"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU367104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50802"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="OBZ91386.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="288" mass="32337" checksum="DA8562A5BD74F6CF" modified="2016-11-30" version="1">MRLRIRHPEGTATLSVSNPEQTVGELKQEIKATLNIDKAIELSGGYPPKIIENDSLKLSDGNVRNGDTLSVRLLDSDHSKEPIVHKNAVQTSDGFLTLREMKDDNSCLFRSVEAEVTHELRQIVAQAISSDEINYSDAMLGMERSKYIEWIQKPNSWGGAIELAILSAYFDLEINSIDVQSGRMDRFGEGKSKERAFVVYSGIHYDAIAMNSQFNGPKELDETRFSLDNEHVVEAAKKLIGDLKKNHKYTDVANFTLRCEQCQKGLKGQKDAQDHAAATGHMRFTEYE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NT22</accession>
    <name>A0A1C7NT22_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Peroxisomal ATPase PEX1</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">Peroxin-1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="16" type="primary">PEX1</name>
        <name evidence="16" type="ORF">A0J61_00085</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="13">
            <dbReference type="Rhea" id="RHEA:13066"/>
        </physiologicalReaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the AAA ATPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000002">
        <property type="protein sequence ID" value="OBZ91846.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NT22"/>
    <dbReference type="FunCoup" id="A0A1C7NT22">
        <property type="interactions" value="442"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NT22"/>
    <dbReference type="InParanoid" id="A0A1C7NT22"/>
    <dbReference type="OrthoDB" id="2187at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005778">
        <property type="term" value="C:peroxisomal membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016558">
        <property type="term" value="P:protein import into peroxisome matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.60:FF:000105">
        <property type="entry name" value="PeRoXisome assembly factor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.40.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.330.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050168">
        <property type="entry name" value="AAA_ATPase_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041569">
        <property type="entry name" value="AAA_lid_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009010">
        <property type="entry name" value="Asp_de-COase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003960">
        <property type="entry name" value="ATPase_AAA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029067">
        <property type="entry name" value="CDC48_domain_2-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015342">
        <property type="entry name" value="PEX1-N_C-lobe"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23077">
        <property type="entry name" value="AAA-FAMILY ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23077:SF12">
        <property type="entry name" value="PEROXISOMAL ATPASE PEX1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17862">
        <property type="entry name" value="AAA_lid_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09262">
        <property type="entry name" value="PEX-1N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50692">
        <property type="entry name" value="ADC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54585">
        <property type="entry name" value="Cdc48 domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00674">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-0962">Peroxisome biogenesis</keyword>
    <keyword evidence="9" id="KW-0653">Protein transport</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="15">
        <location>
            <begin position="491"/>
            <end position="872"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="939"/>
            <end position="965"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="981"/>
            <end position="1001"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="14">
        <location>
            <begin position="939"/>
            <end position="949"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="14">
        <location>
            <begin position="951"/>
            <end position="962"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006914"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00032509"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00034532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00048778"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="OBZ91846.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="1060" mass="117788" checksum="DFC67D98BDB8C332" modified="2016-11-30" version="1">MPKPLIVQYTPTRSCLVNLPHKWVNALLDQKKVPQNVILEISLENKKVYCGWSGEASKPLQPNSVFTHGANSKLDVLELDPQFGTALGFQEGQKVNVDFCRNVPECTTVHVEPLTEDDWEILELHAGYVEENLLSQLRVVYAQQTICVWIHNKTLVRLSVASIEPKQQDYVKLTNQSEVIVAPKVRMPVSNSLASEPSELTATAQKKQPSTHLRVCYSGNMSVSDVSVMMHPDAAIPLLDVNGNAPQVVKISKLLPAFVKNNKEEQQHPEANDLEQFSPAKALFARLHLSSSIPSRHIAIGSVLQSTLSIKEFDLVRVSCTSTKKVALGSLILRQLTNHTNTASTIKLGLDSMKQTQLKLQFEASATQAMKTWLFQQPSEDMAISQGLQIDMIVEEKQETFVVQLGSKKGLFGTSPDPHLEHYALLSPQQQQSLSIEFGEQIQRTSDKPEKQHLPSGVTLGGVDDLLHKIERYALSHLSSRELKDALHVPGSGGILVTGTHGSGKTSVVRHLLQFCRLHQIYTMEIHCSELVDERIPVLKETIQRWFDEAAWHGPTLVFLDDLDRLIPAEVEHADSTRSRHLAELFVTMARLSSQRHPILLIATSQQQQSIHPALITHHIFSELRHLQPPNRDERKQIMQAIMSHGSSVLSQSLPKIDLVTVASETEGFVAADLKAFIERTVHEGAIRSMKENPEAGSLLLTQSDFTRAREGFVPSSLRGVKLQSSGVHWSDIGGLNETRKALLETLEWPTKYAAVFAQCPLRLRSGVKGPEILNKYIGASEKSVRDLFERAQAAKPCVLFFDEFDSIAPRRGHDSTGVTDRVVNQMLTQMDGAEGLDGVYVLAATSRPDLIDPALLRPGRLDKALLCGMPTVEERQEILEALSSKMQFAPHINLRTYAEKTEGFSGADLQGFLYNAHLEAIHSAINIETFKEAQDLKSSKKASNEKSDFVMNTDSSQTQLTKAERGQISQRLAMIKKNVQSRTKKETREESNETVVSSHSEALITHDHLEKSFKSTRPSITAEEAYRLTLIYNEFVTGRTGELPSGEGVKGIGKRSTLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NT40</accession>
    <name>A0A1C7NT40_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_00079</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000002">
        <property type="protein sequence ID" value="OBZ91876.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NT40"/>
    <dbReference type="InParanoid" id="A0A1C7NT40"/>
    <dbReference type="OrthoDB" id="2289027at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ91876.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="117" mass="13013" checksum="425D5BBF2F09FA10" modified="2016-11-30" version="1">MEFFAGSENSIGIAWHQLEQLKQEILAQTGLCAYFQELAEKAGIESDGLLIAYLKAAIDPVLRRVLIYRSPTTFTEAVSVCIEVEPDLANLSQAQILSPTTIGRGSQRYHRQKPNSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NTG2</accession>
    <name>A0A1C7NTG2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">dolichol kinase</fullName>
            <ecNumber evidence="3">2.7.1.108</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">DOLK</name>
        <name evidence="11" type="ORF">A0J61_01165</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the polyprenol kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.108" evidence="3"/>
    <dbReference type="EMBL" id="LUGH01000034">
        <property type="protein sequence ID" value="OBZ90784.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NTG2"/>
    <dbReference type="STRING" id="101091.A0A1C7NTG2"/>
    <dbReference type="InParanoid" id="A0A1C7NTG2"/>
    <dbReference type="OrthoDB" id="377083at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004168">
        <property type="term" value="F:dolichol kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043048">
        <property type="term" value="P:dolichyl monophosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032974">
        <property type="entry name" value="Polypren_kinase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13205:SF15">
        <property type="entry name" value="DOLICHOL KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13205">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 15-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="6 11" id="KW-0418">Kinase</keyword>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="5 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="54"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="79"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="162"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="200"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="230"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="260"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="292"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="332"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="374"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="415"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="472"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="495"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="534"/>
            <end position="553"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="559"/>
            <end position="579"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="599"/>
            <end position="621"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="636"/>
            <end position="653"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010794"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012132"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="OBZ90784.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="675" mass="75780" checksum="708177C7D7D81523" modified="2016-11-30" version="1">MDKAHEPLDADEGFASSSSVEQDQIYEVIRRKRISQLVPQPEVEMQKVLLEDKIKMAPVESILWIVSFLWIFYQLLYTFDYQVIAGWLLTIWLGIGSVRYSSKRKERQHEEQLTTSSDETADQLKAYDGDKQSKVLYNAHLQSVNRIFGANKTSFRANADDGLLCGVLLLPMVAAAKLIDASRKSVDTSQLAYLSARLELVLFMSMVMLILVFVNEYLHPLKRVIRKRGLFVSSICVAAVLTTLLSYSPLVPTLSQTSTLVTVISMTMFQWFLYICVVTLKKCFTLGEMCIISQAGAIVVHGTAEYICASYYPDHMAFYMQYIEVACSTVLIHALVVGMVLIGVLTYPLLRQSRRLAQRPYWRSSSQFLQNKKAWVAISFYGLTAILVFFMIAPICQTVTGENPFMWTLDFLYMSPSRMFLCLYWSLTVVTTIVVWVLVLDFVPQSNQQDPPFYTTKEGKGLTAALNKKRKLFHALAVIMFVPGVLFELSFLQLAFGVALSGFIYLEYLRYFAVWPWGKSLHVFLTEFIDNRDLGPVILSHIYLLLGCASPVWLGSTNVLASLSGILSLGFGDAAASIIGKRYGQYCWPGTKKTVEGTLAFIVAVLSSSWVIVYSAALLGIDEATRFVASAGRSEWFGYSLIVGLTGLLEAFSTQNDNIVIPLYMYALIVLQNSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NW86</accession>
    <name>A0A1C7NW86_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Heat shock protein 90</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">swo1_1</name>
        <name evidence="10" type="ORF">A0J61_00267</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the heat shock protein 90 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000005">
        <property type="protein sequence ID" value="OBZ91694.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NW86"/>
    <dbReference type="FunCoup" id="A0A1C7NW86">
        <property type="interactions" value="534"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NW86"/>
    <dbReference type="InParanoid" id="A0A1C7NW86"/>
    <dbReference type="OrthoDB" id="28737at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd16927">
        <property type="entry name" value="HATPase_Hsp90-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.120.790:FF:000001">
        <property type="entry name" value="Heat shock protein 90 alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.230.80:FF:000001">
        <property type="entry name" value="Heat shock protein 90 alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.11260:FF:000001">
        <property type="entry name" value="Heat shock protein 90 alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.565.10:FF:000001">
        <property type="entry name" value="Heat shock protein HSP 90-alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11260">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.790">
        <property type="entry name" value="Heat shock protein 90, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="entry name" value="Histidine kinase-like ATPase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00505">
        <property type="entry name" value="HSP90"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019805">
        <property type="entry name" value="Heat_shock_protein_90_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037196">
        <property type="entry name" value="HSP90_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001404">
        <property type="entry name" value="Hsp90_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020575">
        <property type="entry name" value="Hsp90_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_Su5_D2-typ_SF"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003555">
        <property type="entry name" value="PRK05218.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11528">
        <property type="entry name" value="HEAT SHOCK PROTEIN 90 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13589">
        <property type="entry name" value="HATPase_c_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00183">
        <property type="entry name" value="HSP90"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002583">
        <property type="entry name" value="Hsp90"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00775">
        <property type="entry name" value="HEATSHOCK90"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110942">
        <property type="entry name" value="HSP90 C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="Ribosomal protein S5 domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00298">
        <property type="entry name" value="HSP90"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0143">Chaperone</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0346">Stress response</keyword>
    <feature type="domain" description="Histidine kinase/HSP90-like ATPase" evidence="9">
        <location>
            <begin position="28"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="218"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="219"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="35"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="39"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="81"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="94"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="100"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="101"/>
            <end position="102"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="121"/>
            <end position="126"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="173"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="372"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR002583-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OBZ91694.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="700" mass="79737" checksum="2320304D6ED44E67" modified="2016-11-30" version="1">MSAETETFSFQAEISQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYQSLTDPSVLDAEKDLYIRITPDKQNNILSIRDTGIGLTKADLVNNLGTIAKSGTKAFMEALSSGADISMIGQFGVGFYSAYLVADKVQVITKHNDDEQYIWESAAGGSFTITRDTVNPPLGRGTEMRLYMKEDQLEYLDEKKIKDIVKKHSEFISYPIQLVVEKEVEKEVSDDEEEVASEEGAKIEEVTDEDDKKDEKKKKTVKETVTENEELNKTKPLWTRNPEDVKSEEYAEFYKALTNDWEDHLAVKHFSVEGQLEFRAILYIPKRAPFDMFETKKKRNNIKLYVRRVFIMDDCEDLIPEWLNFVKGVVDSEDLPLNISREMLQQNKILKVIRKNLVKKCLEMFQEIAEDKENFDKFYEAFSKNIKLGIHEDSQNRGKLADLLRYHSTKSGDEMTSFKDYVTRMPEKQKNIYYITGESRAAVENSPFLEGFKKKGIEVLLMTDPIDEYATTQLKEYEDKKLVCITKDGLELEEDEEEKKAREAEKAEFEGLCKSVKDILGDKVEKVVLSAMLTDSPCVLTTGQFGWSANMERIMKAQALRDSSMSSYMASKKTLELNPTHPIIKALKSKISADANDRTAKDLVTLLYETSLLTSGFSLDDPSSFATRINRMVSLGLSIDEDELATADEPVTEAAAEDNAEVSKMEEVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7LJS7</accession>
    <name>A0A1C7LJS7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">ATPase F1/V1/A1 complex alpha/beta subunit N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">A0J61_11972</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ATPase alpha/beta chains family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01002797">
        <property type="protein sequence ID" value="OBZ63165.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7LJS7"/>
    <dbReference type="STRING" id="101091.A0A1C7LJS7"/>
    <dbReference type="InParanoid" id="A0A1C7LJS7"/>
    <dbReference type="OrthoDB" id="9805536at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045259">
        <property type="term" value="C:proton-transporting ATP synthase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043531">
        <property type="term" value="F:ADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046933">
        <property type="term" value="F:proton-transporting ATP synthase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023366">
        <property type="entry name" value="ATP_synth_asu-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005294">
        <property type="entry name" value="ATP_synth_F1_asu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004100">
        <property type="entry name" value="ATPase_F1/V1/A1_a/bsu_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036121">
        <property type="entry name" value="ATPase_F1/V1/A1_a/bsu_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48082">
        <property type="entry name" value="ATP SYNTHASE SUBUNIT ALPHA, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48082:SF2">
        <property type="entry name" value="ATP SYNTHASE SUBUNIT ALPHA, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02874">
        <property type="entry name" value="ATP-synt_ab_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50615">
        <property type="entry name" value="N-terminal domain of alpha and beta subunits of F1 ATP synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ATPase F1/V1/A1 complex alpha/beta subunit N-terminal" evidence="3">
        <location>
            <begin position="63"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="97"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02874"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OBZ63165.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="97" mass="10230" checksum="DCAA4D4E4777A3AF" modified="2016-11-30" version="1" fragment="single">MLRNVARIARPLAARSLAPAARLNLGAVATAARTYASAKPSTSEVSSILEQRILGANSEVDLQETGRVLSIGDGIARVYGLKNCQAEEMVEFSSGLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2024-05-29" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7M7P8</accession>
    <name>A0A1C7M7P8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_11891</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01002650">
        <property type="protein sequence ID" value="OBZ71064.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7M7P8"/>
    <dbReference type="InParanoid" id="A0A1C7M7P8"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ71064.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="64" mass="7121" checksum="35FEADE7F12D225A" modified="2016-11-30" version="1" fragment="single">MVLKLNSFHSTSSSFGTTNSSYKRAMVYTILSCELKFTNSLMVVGKFTSATSVIKQMPAWIVHI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MTN1</accession>
    <name>A0A1C7MTN1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_11748</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01002425">
        <property type="protein sequence ID" value="OBZ80203.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MTN1"/>
    <dbReference type="InParanoid" id="A0A1C7MTN1"/>
    <dbReference type="OrthoDB" id="2298546at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="108"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="110"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="129"/>
            <end position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ80203.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="139" mass="14920" checksum="4FD3E3D0268E2DFE" modified="2016-11-30" version="1">MSFPRKYNTERHLASCRSRLSTEGSEVIVIRGSFRESASQTSEINNSVSRDSPSLALVYSTSDVDMDNGSFSGQSLSGFGNQNSGILVDNGFSIGSSSTGILNDIEEITTDNGISSDVPSSEPVHLSDEESDDEELEEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MTS4</accession>
    <name>A0A1C7MTS4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Presequence protease mitochondrial-type C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_11711</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01002373">
        <property type="protein sequence ID" value="OBZ80240.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MTS4"/>
    <dbReference type="STRING" id="101091.A0A1C7MTS4"/>
    <dbReference type="InParanoid" id="A0A1C7MTS4"/>
    <dbReference type="OrthoDB" id="10250783at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016485">
        <property type="term" value="P:protein processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.830.10">
        <property type="entry name" value="Metalloenzyme, LuxS/M16 peptidase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011249">
        <property type="entry name" value="Metalloenz_LuxS/M16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055130">
        <property type="entry name" value="PreP_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43016">
        <property type="entry name" value="PRESEQUENCE PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43016:SF13">
        <property type="entry name" value="PRESEQUENCE PROTEASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22516">
        <property type="entry name" value="PreP_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63411">
        <property type="entry name" value="LuxS/MPP-like metallohydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Presequence protease mitochondrial-type C-terminal" evidence="1">
        <location>
            <begin position="1"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF22516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ80240.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="121" mass="14216" checksum="04FA230F4C119A85" modified="2016-11-30" version="1" fragment="single">YRDPRTLETLDTYSKSVEWVQQRNFTDQELTESKLAIFQDVDAPQSVSEEGMLQFIHGISDEMRQWRREALLKVTQDDIKRVAHTYLEKPFQNGSYSTALLGEANERISAEHGWHINEWTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MTY8</accession>
    <name>A0A1C7MTY8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_11724</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01002387">
        <property type="protein sequence ID" value="OBZ80227.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MTY8"/>
    <dbReference type="InParanoid" id="A0A1C7MTY8"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ80227.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="209" mass="23612" checksum="8296E2B5C6C85730" modified="2016-11-30" version="1" fragment="single">RFNWKYFELITSVMSCKILITSYYTSQALRSSIQGHYQESPLAVTCSSMAIVNVEFSVDASEKSQEQPAPKRRRCWALVHSYATESPVDTFNCNQGNCKAVFTGGITSNLLSHFNNVAEEEHGKKNVATKQSFRETLVRLLLTNQLSLNLVNSESFKTLCTGIRNAPNSETVQLPSDTTVVNEIKSMYQQMKPKISELLLQTKKNLFQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MUB1</accession>
    <name>A0A1C7MUB1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">CCHC-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">A0J61_11593</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01002232">
        <property type="protein sequence ID" value="OBZ80357.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MUB1"/>
    <dbReference type="InParanoid" id="A0A1C7MUB1"/>
    <dbReference type="OrthoDB" id="2286764at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.60.10">
        <property type="entry name" value="Zinc finger, CCHC-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001878">
        <property type="entry name" value="Znf_CCHC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036875">
        <property type="entry name" value="Znf_CCHC_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00098">
        <property type="entry name" value="zf-CCHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00343">
        <property type="entry name" value="ZnF_C2HC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57756">
        <property type="entry name" value="Retrovirus zinc finger-like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50158">
        <property type="entry name" value="ZF_CCHC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="CCHC-type" evidence="3">
        <location>
            <begin position="53"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="domain" description="CCHC-type" evidence="3">
        <location>
            <begin position="73"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="113"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="179"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="113"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="187"/>
            <end position="204"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OBZ80357.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="204" mass="23037" checksum="35112C0B3E3EB0D6" modified="2016-11-30" version="1">MVLFTNFVIDTHTPAFATSSGTAVPIQQLSRQLYLSFWDKHAPASFKGAAPVCFYCRQTGHVRRECPKLQNQKCYGCGVKGHTRRFCKQKRDKLQEESTDSLLIAEYEQIKQNRGVAERRDPSTDKPNKTYTGEGPEASRWAPDSTAAYMRGMEADFPSSEDGDLRYDETMFQTKDMDLEIPDLEQSTTTPAEATTSSLSTRRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MUI9</accession>
    <name>A0A1C7MUI9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_11812</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01002527">
        <property type="protein sequence ID" value="OBZ80139.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7MUI9"/>
    <dbReference type="InParanoid" id="A0A1C7MUI9"/>
    <dbReference type="OrthoDB" id="2206543at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="51"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="74"/>
            <end position="89"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ80139.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="297" mass="34277" checksum="B124A348ECD9E158" modified="2016-11-30" version="1">MEISSSFPLTQQSHGDSVETLRALVLQLQEELNRTKAELQQARSEIARIHERQAQPAPITLGSQFTSLPPRQGSAQPQLDSSPQQSLPPWKDQSRIQVMKQTMLERRQQRKERQRDTAARFLQPPSENQGFQYIYLPTKARIPVGQLRTHLRRLNINNSRILDIHYPARNLVALLVHNDYAPELKNHLSQFKITTKDDFDPCNGQNLLDPRYTDNTPEERDSYAKMHHQDRMRRALAHIRQPVKASVARFFFQKGWIDQTDLSAALPPAPTLSHNPLIMDTXMETHDSMPLEDGEEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MUM2</accession>
    <name>A0A1C7MUM2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_11390</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001980">
        <property type="protein sequence ID" value="OBZ80561.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MUM2"/>
    <dbReference type="InParanoid" id="A0A1C7MUM2"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="12"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="24"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="37"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ80561.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="122" mass="14314" checksum="8633CA1816A0B5BD" modified="2016-11-30" version="1">MICKVEKHRRKPQGEKAEETKRQREQRRRRKQKRREVKTPGKRQEFLQPNGRRDQSETKDQPCEQPSLPWGKSVNGCAAEASPHRHVLFGTSRNFSEWWVLHSGGGSISRFPTRCHGEISWP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MUP6</accession>
    <name>A0A1C7MUP6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_11431</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01002029">
        <property type="protein sequence ID" value="OBZ80520.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MUP6"/>
    <dbReference type="InParanoid" id="A0A1C7MUP6"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ80520.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="108" mass="12899" checksum="6921CAD70A3BDE02" modified="2016-11-30" version="1" fragment="single">MSNLIEKLSEYIKENKDASLKGFFYKNLTLLQQHTFTSKEAIRSKMKERFIDFFKKYHPDCDMPSKTPVEIRTLIYKWFYALNEGTGEDIYEQNKQAIDQFLKSETSH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MUY7</accession>
    <name>A0A1C7MUY7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">CCHC-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_11683</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01002339">
        <property type="protein sequence ID" value="OBZ80269.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MUY7"/>
    <dbReference type="InParanoid" id="A0A1C7MUY7"/>
    <dbReference type="OrthoDB" id="427960at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.60.10">
        <property type="entry name" value="Zinc finger, CCHC-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ80269.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="61" mass="7025" checksum="525BF58F3E6C7BF0" modified="2016-11-30" version="1">MGERSFTPFELEEHESCADDHLKANCPKLNFRRKACFICGSYEHLRAKCSLLADNYQSLSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MUZ6</accession>
    <name>A0A1C7MUZ6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">CCHC-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">A0J61_11373</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001965">
        <property type="protein sequence ID" value="OBZ80577.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7MUZ6"/>
    <dbReference type="InParanoid" id="A0A1C7MUZ6"/>
    <dbReference type="OrthoDB" id="2287232at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.60.10">
        <property type="entry name" value="Zinc finger, CCHC-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001878">
        <property type="entry name" value="Znf_CCHC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036875">
        <property type="entry name" value="Znf_CCHC_sf"/>
    </dbReference>
    <dbReference type="SMART" id="SM00343">
        <property type="entry name" value="ZnF_C2HC"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57756">
        <property type="entry name" value="Retrovirus zinc finger-like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50158">
        <property type="entry name" value="ZF_CCHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="CCHC-type" evidence="3">
        <location>
            <begin position="125"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="169"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="205"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="172"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="unsure residue" description="D or N" evidence="4">
        <location>
            <position position="74"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OBZ80577.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="309" mass="33709" checksum="20BE7C613022608B" modified="2016-11-30" version="1" fragment="single">PFIYGRGASGLAQLRDDMFYNLEPFGKIVDCGLDFSAGGAFSGNGFVVLECFDHPVTSSRSLSHLIDWSYHPVDFSVTESIVLLPNPDRVQVKATWASMAPFCRYCHASDHALADCKRRRAATLCYNCHELDHIAKSCPRKNVGSGKKRKAPAPVFALPHPLPVVVPPTPSLEPELPSSSSSSLPELSPVPVLIPETSLSSFASTRQSQRLLKRQPSPEIPETPLALASQSPATCLHCGLQGHSRTTSKHCLKNPKYLRDNSQPTEASLHKLSDLDIDMDDELPDTQLPPLSVPVDXLEPSLVFTLPSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-06-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MV82</accession>
    <name>A0A1C7MV82_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_11284</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001865">
        <property type="protein sequence ID" value="OBZ80667.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MV82"/>
    <dbReference type="InParanoid" id="A0A1C7MV82"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="203"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ80667.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="203" mass="24065" checksum="FD862EC4172A0FCC" modified="2016-11-30" version="1" fragment="single">MMNNNYLSALEEDVVQDKPVLSTKRKVGLKDNGQTADHQGMRIKGLAKLKEEEDCGRLLIQQKINRLHHEHFERKKMEKIKETNRLIEKTNKILKANKPLIPYEKPQSTLPNAKQVEDKALDKLRRWLDQVIEFRFERDIHDEKARKAFEEAIGQLILSFHYFYPDSNAIPMTTYKFVRAHILKTICGDDHHYYKQLMHDIKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MVJ7</accession>
    <name>A0A1C7MVJ7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">RNA-directed DNA polymerase from mobile element jockey</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">pol_6</name>
        <name evidence="2" type="ORF">A0J61_11506</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01002126">
        <property type="protein sequence ID" value="OBZ80446.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7MVJ7"/>
    <dbReference type="InParanoid" id="A0A1C7MVJ7"/>
    <dbReference type="OrthoDB" id="5514950at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003964">
        <property type="term" value="F:RNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043502">
        <property type="entry name" value="DNA/RNA_pol_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000477">
        <property type="entry name" value="RT_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33332">
        <property type="entry name" value="REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00078">
        <property type="entry name" value="RVT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56672">
        <property type="entry name" value="DNA/RNA polymerases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50878">
        <property type="entry name" value="RT_POL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0695">RNA-directed DNA polymerase</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Reverse transcriptase" evidence="1">
        <location>
            <begin position="1"/>
            <end position="153"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ80446.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="368" mass="41913" checksum="867D0BDBA17C0F96" modified="2016-11-30" version="1">MGITPRPLLGLLRNLFDDVHMEVILNNVTSXRFSPITGVLQGSILSPFLYSIYINDLPSLLRPQPLSEAXSPIEAAPSFNCLLYADDVVLIADRARMPSLLQMCEHHSRQVGYRWNPSKCVILDPHPPPSFPYTLYDSXIPLQSSFSYLGVPFSPGGYISALDAVSINITKALRTLNQLASIGMNPRGFSPLLSTRFYVQIVRPQLEYGLAITPLTKYITDQLEQAQNQCIRRIFGGSKHSSIQVMLHLAKLPSMKDRAHFLQAHFLLRSLHLPPDTLLSRLLPHIRSSLSRSTWYRLSKSPLWRKCQPNIDSLTRRSLYRLYMQERHEDLLRRQSSHRHVLLSHCRPIICTDPVDQSYVRILSSGYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MVQ4</accession>
    <name>A0A1C7MVQ4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Retrovirus-related Pol polyprotein from transposon 17.6</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">pol_9</name>
        <name evidence="2" type="ORF">A0J61_11048</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001622">
        <property type="protein sequence ID" value="OBZ80903.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MVQ4"/>
    <dbReference type="STRING" id="101091.A0A1C7MVQ4"/>
    <dbReference type="InParanoid" id="A0A1C7MVQ4"/>
    <dbReference type="OrthoDB" id="2290343at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01647">
        <property type="entry name" value="RT_LTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.10.10">
        <property type="entry name" value="HIV Type 1 Reverse Transcriptase, subunit A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043502">
        <property type="entry name" value="DNA/RNA_pol_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000477">
        <property type="entry name" value="RT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051320">
        <property type="entry name" value="Viral_Replic_Matur_Polypro"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33064">
        <property type="entry name" value="POL PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33064:SF37">
        <property type="entry name" value="RIBONUCLEASE H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00078">
        <property type="entry name" value="RVT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56672">
        <property type="entry name" value="DNA/RNA polymerases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50878">
        <property type="entry name" value="RT_POL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Reverse transcriptase" evidence="1">
        <location>
            <begin position="1"/>
            <end position="233"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ80903.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="266" mass="30152" checksum="AF0DE3D5A07AC058" modified="2016-11-30" version="1">MTQKPLLKKGKTTKPKAVWTLTLELPQEAIAETEMNSLEATQQVFPGSDVMIHEGVDANGQKQQYTSVVIQAQAGKKDPFRLCLNYRPINIVIKDSGYLIPNINFLFTILGQATYFSAFDCLKGFWQLRLDEKSKGLTGFATTFGQFRWTRLPMGLKSSPAAWQKVMDTIFFEELYRFVLIYIDDALIFSTSFDNHLVHLETILKKAAQAGLSLSVTKCKFGYKEIPVLGHILSTDGFKMDQKKIRKVQEYPTPVNLTALNRFIAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-06-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MVT1</accession>
    <name>A0A1C7MVT1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_10936</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001524">
        <property type="protein sequence ID" value="OBZ81015.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MVT1"/>
    <dbReference type="InParanoid" id="A0A1C7MVT1"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ81015.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="76" mass="8915" checksum="14B40003C063ACA2" modified="2016-11-30" version="1">MTDKHWEAIDGFVYEKQLIQPRICPETNSLRLECEHNDPTECIRLFQDVLSNHVILSLKCANIHGEIEIQEHYVPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MWL1</accession>
    <name>A0A1C7MWL1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_10759</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001373">
        <property type="protein sequence ID" value="OBZ81192.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MWL1"/>
    <dbReference type="InParanoid" id="A0A1C7MWL1"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ81192.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="30" mass="3165" checksum="ED92D4BA3C3BCA2C" modified="2016-11-30" version="1" fragment="single">MASATNNIVPAPKTNNLVNEDTEMTSADSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MY64</accession>
    <name>A0A1C7MY64_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">REJ domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_10173</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001058">
        <property type="protein sequence ID" value="OBZ81780.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MY64"/>
    <dbReference type="InParanoid" id="A0A1C7MY64"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008889352" description="REJ domain-containing protein" evidence="2">
        <location>
            <begin position="22"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="39"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="48"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="69"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="102"/>
            <end position="112"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ81780.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="112" mass="12138" checksum="CBEDC3D60B59C406" modified="2016-11-30" version="1">MSSKSIVTFLLLFVFLGPFKPRNTCTILTKFIITTPTTTVPTPTNVTQISSSSNTPKYISYRSKRLRRSSSSSSSSSSSSTSSGTSNMPATKTKVAKPATQRIPTTMTRNSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MY91</accession>
    <name>A0A1C7MY91_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Pyrroline-5-carboxylate reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">proC_1</name>
        <name evidence="7" type="ORF">A0J61_10144</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the pyrroline-5-carboxylate reductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001050">
        <property type="protein sequence ID" value="OBZ81807.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MY91"/>
    <dbReference type="FunCoup" id="A0A1C7MY91">
        <property type="interactions" value="166"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7MY91"/>
    <dbReference type="InParanoid" id="A0A1C7MY91"/>
    <dbReference type="OrthoDB" id="10263291at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004735">
        <property type="term" value="F:pyrroline-5-carboxylate reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055129">
        <property type="term" value="P:L-proline biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.3730.10:FF:000001">
        <property type="entry name" value="Pyrroline-5-carboxylate reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3730.10">
        <property type="entry name" value="ProC C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01925">
        <property type="entry name" value="P5C_reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008927">
        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028939">
        <property type="entry name" value="P5C_Rdtase_cat_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029036">
        <property type="entry name" value="P5CR_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000304">
        <property type="entry name" value="Pyrroline-COOH_reductase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00112">
        <property type="entry name" value="proC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11645">
        <property type="entry name" value="PYRROLINE-5-CARBOXYLATE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11645:SF0">
        <property type="entry name" value="PYRROLINE-5-CARBOXYLATE REDUCTASE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03807">
        <property type="entry name" value="F420_oxidored"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14748">
        <property type="entry name" value="P5CR_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000193">
        <property type="entry name" value="Pyrrol-5-carb_rd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48179">
        <property type="entry name" value="6-phosphogluconate dehydrogenase C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pyrroline-5-carboxylate reductase catalytic N-terminal" evidence="5">
        <location>
            <begin position="6"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="domain" description="Pyrroline-5-carboxylate reductase dimerisation" evidence="6">
        <location>
            <begin position="172"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="9"/>
            <end position="14"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="37"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="60"/>
        </location>
        <ligand>
            <name>NADPH</name>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="73"/>
            <end position="76"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR000193-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF03807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF14748"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OBZ81807.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="283" mass="30585" checksum="D663D87176F3D6D8" modified="2016-11-30" version="1">MTIPVIAFIGGGNMAEAILGGLYHPSVGHPHTHLRYSEPLEERRHYMMNKYPDAMASDDNAAVVDGADIVILAVKPQVLRTVMKDLAPTLHKNKHILIISIAAGIETEAILRWLDPQGYEAPLIRIMPNTPSLIGEGAVGLYATAAVSEEQKKLTERLMGSVSKVLSWVTSESLVDTITGMSGSGPAYFFLMMEAMENAGVAAGLSREESKSLTLQTCLGAARMAMESEDDLATLRRKVTSPHGTTEAAIKSMEAADIRKVIHDAVFAATDRSRELAEELGRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MYK9</accession>
    <name>A0A1C7MYK9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 10">Conserved oligomeric Golgi complex subunit 6</fullName>
            <shortName evidence="10">COG complex subunit 6</shortName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8 10">Component of oligomeric Golgi complex 6</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="15" type="primary">Cog6</name>
        <name evidence="15" type="ORF">A0J61_09956</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Acts as a component of the peripheral membrane COG complex that is involved in intra-Golgi protein trafficking. COG is located at the cis-Golgi, and regulates tethering of retrograde intra-Golgi vesicles and possibly a number of other membrane trafficking events.</text>
    </comment>
    <comment type="function">
        <text evidence="10">Acts as component of the peripheral membrane COG complex that is involved in intra-Golgi protein trafficking. COG is located at the cis-Golgi, and regulates tethering of retrograde intra-Golgi vesicles and possibly a number of other membrane trafficking events.</text>
    </comment>
    <comment type="subunit">
        <text evidence="10">Component of the conserved oligomeric Golgi complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 10">Golgi apparatus membrane</location>
            <topology evidence="1 10">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the COG6 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000982">
        <property type="protein sequence ID" value="OBZ81995.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MYK9"/>
    <dbReference type="FunCoup" id="A0A1C7MYK9">
        <property type="interactions" value="308"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7MYK9"/>
    <dbReference type="InParanoid" id="A0A1C7MYK9"/>
    <dbReference type="OrthoDB" id="272987at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017119">
        <property type="term" value="C:Golgi transport complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006891">
        <property type="term" value="P:intra-Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010490">
        <property type="entry name" value="COG6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048369">
        <property type="entry name" value="COG6_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048368">
        <property type="entry name" value="COG6_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21506">
        <property type="entry name" value="COMPONENT OF OLIGOMERIC GOLGI COMPLEX 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21506:SF0">
        <property type="entry name" value="CONSERVED OLIGOMERIC GOLGI COMPLEX SUBUNIT 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20653">
        <property type="entry name" value="COG6_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06419">
        <property type="entry name" value="COG6_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01087">
        <property type="entry name" value="COG6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6 10" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="7 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 10" id="KW-0653">Protein transport</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Conserved oligomeric complex COG6 N-terminal" evidence="13">
        <location>
            <begin position="49"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="domain" description="Conserved Oligomeric Golgi complex subunit 6 C-terminal" evidence="14">
        <location>
            <begin position="192"/>
            <end position="652"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="11">
        <location>
            <begin position="89"/>
            <end position="116"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004395"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00020973"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00031348"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00043873"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU365075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF06419"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF20653"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="OBZ81995.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="660" mass="74177" checksum="D7C9704917982E1A" modified="2016-11-30" version="1">MEAKSPPTIYGSPSFNSKPNKPLAAKLSRVLNSSTSEDAKIKAALTALSDISDLDEVSLRRNLQGTIERKEIKTNKRFLGAFEKVVVQFDKLELQLSQMETVCQDMKQRLVTVESQTANMIEQANIMQKHSSACNTQIVLVDRFLEKFTLTQQEIKLLSSSSEPISHEFFDALEHLHAIHNDCQLLLTTKHQTAGRDIIESMAQYQETAYEKLHRWTQYESRTCFGGDSIDVSTLMTKSLRALMLRPVLFQTIIDEIASARHDAVARAFMNALTRGGPGGTPRPIELQAPDPLRYIGDMLAWVHQACASEKEMLDSLFQLPNQSTTSTPVSVSVKDTIDDLLGYTMEGIVRPLRSRMEQVLVLQPGAITSYKVANLIQFYTMTLSKLMRKNSTLERVLHEMTELAYKYFFKTLSAQADRLIQSAEPPERSLSITPAIRKMTIQLKEILASYDSSLIISTTNTEEFSAFDFSEILDAIIEPLINACELSVAKLDKLDQDVYIVNCLHHIQTVMAPYTFTKQKRESIAARTNDLLTEMASEEFQQLLDRAGLLPIKKVLDTRDPDTPLSSLPHMDTASLTEAMSKFDSFLVLMSADVSPQLDKLSSTQHYQQVQSGAISLLLDTYKKVSQQIHDPKNGYPDPAQVLPRTVKDMEAIFSFALE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MYP6</accession>
    <name>A0A1C7MYP6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_10029</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001006">
        <property type="protein sequence ID" value="OBZ81922.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MYP6"/>
    <dbReference type="STRING" id="101091.A0A1C7MYP6"/>
    <dbReference type="InParanoid" id="A0A1C7MYP6"/>
    <dbReference type="OrthoDB" id="2443140at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009986">
        <property type="term" value="C:cell surface"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030427">
        <property type="term" value="C:site of polarized growth"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005034">
        <property type="term" value="F:osmosensor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030010">
        <property type="term" value="P:establishment of cell polarity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031505">
        <property type="term" value="P:fungal-type cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006972">
        <property type="term" value="P:hyperosmotic response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007232">
        <property type="term" value="P:osmosensory signaling pathway via Sho1 osmosensor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001402">
        <property type="term" value="P:signal transduction involved in filamentous growth"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039295">
        <property type="entry name" value="MSB2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35778">
        <property type="entry name" value="SIGNALING MUCIN HKR1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35778:SF1">
        <property type="entry name" value="SIGNALING MUCIN HKR1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="414"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="54"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="372"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="67"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="372"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="489"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ81922.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="489" mass="52145" checksum="0A2BBFE7DB64251E" modified="2016-11-30" version="1" fragment="single">TTTAKEVTTPHAQKPTTTNEEVATTTANEITITHVHKPTTTKKDAVITTTNEAAATHRPATTSEGVATTTADDPTTTPIHNPTTTYNDADTSTVIDRTTVKAPSETITSRAEDVKTTTNAAAATTTNAVPVTTNRDGSYTITSSANSSAGQPTRTGNPNTLITGTTVAEISNSQPQATSTYKYQTLSWLTDRFIYTTESVTVSTTTSATEYTLTANSTGSLPTTTTTKMENTLPQFITANINAVIPNTSDITHVRFNDILYSTLVKNAVLTAQLVQEIPSILSNTLEITPDDIIVLTITQSLASSVNVNQKKRSVGASDGILVTMALPKDQVQELQSDIYNASSTLYQTSNGQLPTFIDRTYNITSLATVSPGTSSGTINNPNGDTDIHTNNGHADDSDHVDVPAEGSKLSKGGIIGICIGVGACVYVAATIVGVKVYRNHKKEKEDNAIEQHMIFAESISSPVLHEDSLGWTETPYQRNQIHMSHLSY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N044</accession>
    <name>A0A1C7N044_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">RRM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">A0J61_09559</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000878">
        <property type="protein sequence ID" value="OBZ82391.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N044"/>
    <dbReference type="InParanoid" id="A0A1C7N044"/>
    <dbReference type="OrthoDB" id="336240at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd12254">
        <property type="entry name" value="RRM_hnRNPH_ESRPs_RBM12_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050666">
        <property type="entry name" value="ESRP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13976">
        <property type="entry name" value="HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 4" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="3" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="5">
        <location>
            <begin position="86"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="6">
        <location>
            <begin position="161"/>
            <end position="245"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OBZ82391.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="616" mass="69403" checksum="EB162A730DE71D96" modified="2016-11-30" version="1">MYEPIDKNELSINLNHINHKPSSPICPPSPLTPLTNHFNASSYSLFHTGNDYGWFSSSNAPLFRNHSTVVEDCAYKRITQNYTPVCSFCLDKSNIQQLFASSCGQHQFCHSCLSSQKSHLLLQGICPFCEQANGVQSNQVPLKSDSSFVSNYATYSPHYYPCVKLTNIPWDVSQQDVKQFFFNCKNPSANTYTQSIHIMMDRTTGKTLSDAYVEFATTMDMKRAIETKNQKPLKGRIVSVIECTQEELLSVVFPKWRGQFHGISAIPPVVGGVSGCPPFITREEINSLLVVCKNYKLHFSRKCAERPFENIISVITKHPWHQAHLFISTMHRDHIYEMLKLSIESLRTHLAKDYVQIDNTLLERLVRAGIMCPAFTERQKATLLQTARIECPQEITSYLVSPSPVVSLAPPGLQLSKNSEYSNSNNKGSNINVPSILFTPNSPTLNLPTGLKQSASPYHFVPQKTYSLSASQKEEPPYLWSKIQEGDKTEPSCAPSINSPVSSLIRDIHQYCHFNDTPDNKKQLSGFDSQPQLTKNGVSLLFQPTNNNTMENXYVQQKQSIGSQSQLQELYYQKQQTLPWTPSFTSKPNNSDIWRMPTSPTAEPNHMVASESVLIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N0A9</accession>
    <name>A0A1C7N0A9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">sphingolipid C(9)-methyltransferase</fullName>
            <ecNumber evidence="14">2.1.1.317</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="primary">FAMT</name>
        <name evidence="16" type="ORF">A0J61_09844</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="2">Lipid metabolism; sphingolipid metabolism.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3">Sphingolipid metabolism.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the CFA/CMAS family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.317" evidence="14"/>
    <dbReference type="EMBL" id="LUGH01000952">
        <property type="protein sequence ID" value="OBZ82106.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N0A9"/>
    <dbReference type="STRING" id="101091.A0A1C7N0A9"/>
    <dbReference type="InParanoid" id="A0A1C7N0A9"/>
    <dbReference type="OrthoDB" id="412182at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006665">
        <property type="term" value="P:sphingolipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052290">
        <property type="entry name" value="Sphingo_C9-MT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45197:SF1">
        <property type="entry name" value="SPHINGOLIPID C9-METHYLTRANSFERASE A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45197">
        <property type="entry name" value="SYNTHASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_7G04190)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02353">
        <property type="entry name" value="CMAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="12" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="13 15" id="KW-0472">Membrane</keyword>
    <keyword evidence="6 16" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="10" id="KW-0746">Sphingolipid metabolism</keyword>
    <keyword evidence="7 16" id="KW-0808">Transferase</keyword>
    <keyword evidence="9 15" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="11 15" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="70"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="92"/>
            <end position="112"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004760"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010815"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00039020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="OBZ82106.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="510" mass="59443" checksum="D98D1BB32A7D09C8" modified="2016-11-30" version="1">MTLPIQQDFKIRPVKIKKPDKLVSRKDKGRVAFQREKRMSSQFKPTTWAAINNATLPAEGAGNQTFDNRVLFGVTVGVPAFVAYTFGLPLWFFPILTLLLFLPLLACTLYLYSRFAPRYRNRVPLPGKPIEHYLTFHDPELKSQYHGRNKIPMETFFEAYFVGKVDFNGDALEIMELRHDWAAFQFTYGQFKFFLTQWLPETFWHSREQDENQVRDHYDRGNDFYEAFLGPLMVYTSGIITDPTKKESLEELQENKMKLICEKLHMKEGDKHLDIGCGWGTLVAYAAKEYNTRSTGVTLARNQVAFGEKRIEDWNVKGKADLLCMDYRDIPKNHKYDKITAVEMAEHVGLRRFQTFLTEVRELLEDDGLFYMQVAGLRASWQYEDFIWGLFMAKYIFPGADASTPLYWYIKQLETAGFEIHNVDTVGVHYSATLNRWYDNWLKNKEAMRAKYGDNLVRVWEIFLSWSTIVARQGGATCFQIVANKNRNSYDRTQLICNRTNPAAWTSKRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N0L0</accession>
    <name>A0A1C7N0L0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_09413</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000845">
        <property type="protein sequence ID" value="OBZ82538.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N0L0"/>
    <dbReference type="STRING" id="101091.A0A1C7N0L0"/>
    <dbReference type="InParanoid" id="A0A1C7N0L0"/>
    <dbReference type="OrthoDB" id="3044029at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008889398" evidence="2">
        <location>
            <begin position="23"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="179"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="220"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="228"/>
            <end position="240"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ82538.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="359" mass="39810" checksum="8080BB104507F67B" modified="2016-11-30" version="1">MKLSVSLFTTSALAIAASLVQAQSDSANSTDYYPLTTIVSQNDFCLFLPPQPGLEVAINEDNGIPFCFKEDRVKNATQFPEGFITTAHYLKTSSYVQVTGFFDHTKYKLSDTDGGGQYDTHHGGKPIGAKCLGYNYFVSVIEPDINRFCIRCCLNTEDCPTGRSGYGCLRVIDGDYTNDNNMINGTDSTDTDTTESNLSNTHENSVYNELDFLVAHKNAAPSQAGTSADDDDEEDDDDTDSSSNDKIAQEIESLKNDSYSASEIKEKWNAFSQQLSANYPHASEQVDDLNTVASSLTTTDQWKAFFELVSDKIIQFQEDSDDNATLTDDTKASSTDTHTNEDLDWLFEHRRSHDNQATW</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N0U4</accession>
    <name>A0A1C7N0U4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Ribosome biogenesis protein brx1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">brx1</name>
        <name evidence="7" type="ORF">A0J61_09187</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the BRX1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000793">
        <property type="protein sequence ID" value="OBZ82765.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N0U4"/>
    <dbReference type="FunCoup" id="A0A1C7N0U4">
        <property type="interactions" value="719"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N0U4"/>
    <dbReference type="InParanoid" id="A0A1C7N0U4"/>
    <dbReference type="OrthoDB" id="1638493at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030687">
        <property type="term" value="C:preribosome, large subunit precursor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008097">
        <property type="term" value="F:5S rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042134">
        <property type="term" value="F:rRNA primary transcript binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000464">
        <property type="term" value="P:endonucleolytic cleavage in ITS1 upstream of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000465">
        <property type="term" value="P:exonucleolytic trimming to generate mature 5'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000027">
        <property type="term" value="P:ribosomal large subunit assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007109">
        <property type="entry name" value="Brix"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026532">
        <property type="entry name" value="BRX1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13634">
        <property type="entry name" value="RIBOSOME BIOGENESIS PROTEIN BRIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13634:SF0">
        <property type="entry name" value="RIBOSOME BIOGENESIS PROTEIN BRX1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04427">
        <property type="entry name" value="Brix"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00879">
        <property type="entry name" value="Brix"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52954">
        <property type="entry name" value="Class II aaRS ABD-related"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50833">
        <property type="entry name" value="BRIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0690">Ribosome biogenesis</keyword>
    <feature type="domain" description="Brix" evidence="6">
        <location>
            <begin position="28"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="262"/>
            <end position="291"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006369"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OBZ82765.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="291" mass="34034" checksum="03E2577DB2ED466E" modified="2016-11-30" version="1">MSTLFKTAELVKNKSNEAKSKDKRINKQRVMMLCSRGVTYRYRHLLSDLEAMMPHSKKDAKLDTKNNLYILNELADLNNCNNAVFFEVRKKQDLYVWMAKTPNGPSVKFHLQNLHTMDELKMTGNCLKGSRHILSFDKSFDSAPHWSLLKELLGQVFNVPKGSRRSKPFIDHVLSFSIVDNRVWFRNYQIVEKNAQNTPGYSPMDKDDISLVEIGPRFCLTPIRIFEGSFGGPTVYENPEFIHPNFVRSAIRKDKLEKYTKRQKNNFERENRIRMAEESRETETSDKRVFQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N0V2</accession>
    <name>A0A1C7N0V2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="14">Complex I-B22</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="15">NADH-ubiquinone oxidoreductase B22 subunit</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="17" type="primary">CIB22</name>
        <name evidence="17" type="ORF">A0J61_09693</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed to be not involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Mammalian complex I is composed of 45 different subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion inner membrane</location>
            <topology evidence="2">Peripheral membrane protein</topology>
            <orientation evidence="2">Matrix side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the complex I LYR family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000911">
        <property type="protein sequence ID" value="OBZ82259.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N0V2"/>
    <dbReference type="STRING" id="101091.A0A1C7N0V2"/>
    <dbReference type="InParanoid" id="A0A1C7N0V2"/>
    <dbReference type="OrthoDB" id="13598at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006120">
        <property type="term" value="P:mitochondrial electron transport, NADH to ubiquinone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd20263">
        <property type="entry name" value="Complex1_LYR_NDUFB9_LYRM3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008011">
        <property type="entry name" value="Complex1_LYR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045292">
        <property type="entry name" value="Complex1_LYR_NDUFB9_LYRM3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033034">
        <property type="entry name" value="NDUFB9"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12868:SF0">
        <property type="entry name" value="NADH DEHYDROGENASE [UBIQUINONE] 1 BETA SUBCOMPLEX SUBUNIT 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12868">
        <property type="entry name" value="NADH-UBIQUINONE OXIDOREDUCTASE B22 SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05347">
        <property type="entry name" value="Complex1_LYR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0007">Acetylation</keyword>
    <keyword evidence="10" id="KW-0249">Electron transport</keyword>
    <keyword evidence="13" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="9" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="7" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0679">Respiratory chain</keyword>
    <keyword evidence="6" id="KW-0813">Transport</keyword>
    <keyword evidence="17" id="KW-0830">Ubiquinone</keyword>
    <feature type="domain" description="Complex 1 LYR protein" evidence="16">
        <location>
            <begin position="9"/>
            <end position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002920"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009508"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00018684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022660"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022990"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00030192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00032528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF05347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="OBZ82259.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="100" mass="11887" checksum="C05E3E5E9C6F18E7" modified="2016-11-30" version="1">MSAAHRLHVQSLYKRSLKLSLDWYIQRDLWRQKALQIRAQFEQNKHVTNPKEIQQLVQNAENQLKEWAHPDPYKLPMGPEGTKWERNLPPIVHDAAAHHH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-06-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N0X8</accession>
    <name>A0A1C7N0X8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_09155</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000785">
        <property type="protein sequence ID" value="OBZ82795.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N0X8"/>
    <dbReference type="InParanoid" id="A0A1C7N0X8"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="40"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ82795.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="60" mass="7113" checksum="FF335D2EDC3ACAC9" modified="2016-11-30" version="1" fragment="single">MEENSSLKNSSTTQHNEYIQRLLGYFRMSQPTDHLRNAIKKPLFGPELRDSPENMQTRFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N0Y7</accession>
    <name>A0A1C7N0Y7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_10947</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001531">
        <property type="protein sequence ID" value="OBZ81004.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N0Y7"/>
    <dbReference type="STRING" id="101091.A0A1C7N0Y7"/>
    <dbReference type="InParanoid" id="A0A1C7N0Y7"/>
    <dbReference type="OrthoDB" id="2277465at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00303">
        <property type="entry name" value="retropepsin_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.70.10">
        <property type="entry name" value="Acid Proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021109">
        <property type="entry name" value="Peptidase_aspartic_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13650">
        <property type="entry name" value="Asp_protease_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50630">
        <property type="entry name" value="Acid proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="232"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ81004.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="232" mass="25013" checksum="704BB75990B66596" modified="2016-11-30" version="1" fragment="single">MVTPSSSNVKTSSLNAIDSAATEPDYDRSFSIKSTSHNKVVDSSSYVSSTSVSNVSHNEVTHITPGTIHECENALSYQNTSLSTSVNMKDTSGNSTCVPLELMPITTQLVSLILNTVVSCNLPLYHGVDTSLNGLPLDIHILIDSGASENYISPKISDTKAGMHHHVHGREVETAGGNTSPITDRVVFSLNLQGHSSPVSAFVFDTKFDVILGRSWLKSHTPKANWLDDSWI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N1R1</accession>
    <name>A0A1C7N1R1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">BTB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_09020</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000756">
        <property type="protein sequence ID" value="OBZ82931.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N1R1"/>
    <dbReference type="InParanoid" id="A0A1C7N1R1"/>
    <dbReference type="OrthoDB" id="6359943at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47369">
        <property type="entry name" value="BTB/POZ DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47369:SF2">
        <property type="entry name" value="BTB_POZ DOMAIN-CONTAINING PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="410"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="498"/>
            <end position="519"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="410"/>
            <end position="420"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ82931.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="749" mass="86377" checksum="B9A1CB0DA9465AEB" modified="2016-11-30" version="1">MKVNSKLEKHLLEDMFERSLFSDLSLVFLHPSFPIAMRYNVHKAIVSQSPFLHKLLEHASQNDIHTTLNIDMAKALSNCEFILAPSHHIVRRQWQKTESKSSQKSNKNDRLLSSHIRFVLKWMYCLNKQDLMRGMDDNDTLRILSVAVLFDLHDLTQACVHRYTQEQLSLDSVMRDLDTVCQLPRGHPAYLQLRDAALLLLFRFGPENANRLAMLPADYMADVLSADLLFVECEFDRYCLLRAVLMAYMQSIGKITWTASGPVDQNAKRLSGFVRPLRPMLSTTTTTATTSLSADTVRSRKRRRIPSQELEDTADLLSTKQPRLNRLSFSALVPFQKLLADATSGDIIDKATVLSYLLRTTVNYSNMSFEQLTCVRQDGIVDEGIVFRALWQREALERVLFPSTYHQQTQLHSSRSNSPIPATIREGDDQERSKALNEYFDVDQSEAQEKRRILLLGTPKFRFRSSVYLDPPSPENGWRCEEKYVSNEVISDELANVFDDDDDDESDHSVWSASEDEEQTSSQIVQSALDNLDILPKKLKKSKRVVTKTPYKLYRKIFYSEAQTILGISYRVQIEAQVMPRHRLFIQDDDLEKLQEELLYSDHHEDELVMVCRFELQRDMQQISTALVEIKKEKDQQDTIMSPKNQQPIIPVNPPNSQNYRINTQLRDKTRIHYWIYCLNRHEGILENEQIDPEDRALVAVTEQRERENGEPGEMGPGYVGQVLVEADLQKGVQIDTTVALEIFGFHKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N2V4</accession>
    <name>A0A1C7N2V4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Chloroperoxidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">CPO</name>
        <name evidence="10" type="ORF">A0J61_08582</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>heme b</name>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the chloroperoxidase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000675">
        <property type="protein sequence ID" value="OBZ83367.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N2V4"/>
    <dbReference type="STRING" id="101091.A0A1C7N2V4"/>
    <dbReference type="InParanoid" id="A0A1C7N2V4"/>
    <dbReference type="OrthoDB" id="407298at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004601">
        <property type="term" value="F:peroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.489.10">
        <property type="entry name" value="Chloroperoxidase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000028">
        <property type="entry name" value="Chloroperoxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036851">
        <property type="entry name" value="Chloroperoxidase-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33577:SF18">
        <property type="entry name" value="HEME HALOPEROXIDASE FAMILY PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33577">
        <property type="entry name" value="STERIGMATOCYSTIN BIOSYNTHESIS PEROXIDASE STCC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01328">
        <property type="entry name" value="Peroxidase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47571">
        <property type="entry name" value="Cloroperoxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51405">
        <property type="entry name" value="HEME_HALOPEROXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0349">Heme</keyword>
    <keyword evidence="6" id="KW-0408">Iron</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="2 10" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="21"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="domain" description="Heme haloperoxidase family profile" evidence="9">
        <location>
            <begin position="51"/>
            <end position="246"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00025795"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OBZ83367.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="268" mass="31085" checksum="4440D296C93389C2" modified="2016-11-30" version="1">MSHIKRDTGHHQKKLKISPQRLLSATLGAVLAYIVFHILLVERKGRQGLTTPEQWKQLIKSHPYERKPTDVRSPCPMLNTLANHGFIARDGRDIKLDNFFDAMMLMGAPPTITFAFLKYVFVAYKEASPTSSFLSQFQSLESLDLHRLFVPRIIEHDVSLSRLDQGISNQTSPVPKFVERMIKIAHYKNQGKLKHTFTRRNENDARRIRREGQLATKHLESFLLHERFPEDWYPRETPLGIVDVLIKPMDCWIGLHKSKADLRLLDQI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N2V6</accession>
    <name>A0A1C7N2V6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="9">U5 small nuclear ribonucleoprotein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">Snrnp40</name>
        <name evidence="9" type="ORF">A0J61_08495</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000660">
        <property type="protein sequence ID" value="OBZ83453.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N2V6"/>
    <dbReference type="FunCoup" id="A0A1C7N2V6">
        <property type="interactions" value="1093"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N2V6"/>
    <dbReference type="InParanoid" id="A0A1C7N2V6"/>
    <dbReference type="OrthoDB" id="1068471at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071013">
        <property type="term" value="C:catalytic step 2 spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071014">
        <property type="term" value="C:post-mRNA release spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005682">
        <property type="term" value="C:U5 snRNP"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000375">
        <property type="term" value="P:RNA splicing, via transesterification reactions"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.10:FF:000229">
        <property type="entry name" value="Small nuclear ribonucleoprotein U5 subunit 40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052234">
        <property type="entry name" value="U5_snRNP_Component"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44006">
        <property type="entry name" value="U5 SMALL NUCLEAR RIBONUCLEOPROTEIN 40 KDA PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44006:SF1">
        <property type="entry name" value="U5 SMALL NUCLEAR RIBONUCLEOPROTEIN 40 KDA PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="5" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="9" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 7" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="7">
        <location>
            <begin position="61"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="7">
        <location>
            <begin position="104"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="7">
        <location>
            <begin position="146"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="7">
        <location>
            <begin position="188"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="7">
        <location>
            <begin position="230"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="7">
        <location>
            <begin position="292"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="7">
        <location>
            <begin position="322"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="24"/>
            <end position="33"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OBZ83453.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="361" mass="40019" checksum="2F89B356DD116D36" modified="2016-11-30" version="1">MAEKRQAESSNGGTLIKRAKSDTQDNSQSLINLSDQRSGTRNAIVGTIKRTSGLEAPVMQLTGHNGEIYTCQFDPSGEYIASAGFDRQILLWNTYGEVKNYGILKGHTNAIMELHWSRDGSQIFSCSADKTVGIFDAKTGERVRRWRGHSAVVNSCQVVRRGPELVVSGSDDRTVKIWDHRTKEAVHTFDHDYPITSVSFSDAGDMVFAGGLDNEIHAWDVRKHQSVYSLKGHADTVTGMALSPDGSHLLTNAMDNTVRVWDIKPFAPTDRCLKIFEGAPHGYEKNLIRPCWSTDGSQIACGSADRTVVIWQVENRKILYKLPGHKGCVNDVDWHPKEPIVMSASTDKTMFLGEVKPTKLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N324</accession>
    <name>A0A1C7N324_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Kinesin-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">KINH_1</name>
        <name evidence="14" type="ORF">A0J61_08418</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9 10">Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000645">
        <property type="protein sequence ID" value="OBZ83535.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N324"/>
    <dbReference type="STRING" id="101091.A0A1C7N324"/>
    <dbReference type="InParanoid" id="A0A1C7N324"/>
    <dbReference type="OrthoDB" id="3176171at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005875">
        <property type="term" value="C:microtubule associated complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008017">
        <property type="term" value="F:microtubule binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003777">
        <property type="term" value="F:microtubule motor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007018">
        <property type="term" value="P:microtubule-based movement"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007052">
        <property type="term" value="P:mitotic spindle organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051231">
        <property type="term" value="P:spindle elongation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd23649">
        <property type="entry name" value="Khc_CBD_cc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01369">
        <property type="entry name" value="KISc_KHC_KIF5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.850.10:FF:000031">
        <property type="entry name" value="Kinesin-like protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.850.10">
        <property type="entry name" value="Kinesin motor domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059182">
        <property type="entry name" value="Khc_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027640">
        <property type="entry name" value="Kinesin-like_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019821">
        <property type="entry name" value="Kinesin_motor_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001752">
        <property type="entry name" value="Kinesin_motor_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036961">
        <property type="entry name" value="Kinesin_motor_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47969">
        <property type="entry name" value="CHROMOSOME-ASSOCIATED KINESIN KIF4A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47969:SF15">
        <property type="entry name" value="CHROMOSOME-ASSOCIATED KINESIN KIF4A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00225">
        <property type="entry name" value="Kinesin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00380">
        <property type="entry name" value="KINESINHEAVY"/>
    </dbReference>
    <dbReference type="SMART" id="SM00129">
        <property type="entry name" value="KISc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00411">
        <property type="entry name" value="KINESIN_MOTOR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50067">
        <property type="entry name" value="KINESIN_MOTOR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 9 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 11" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="3 10" id="KW-0493">Microtubule</keyword>
    <keyword evidence="7 9 10" id="KW-0505">Motor protein</keyword>
    <keyword evidence="4 9 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Kinesin motor" evidence="13">
        <location>
            <begin position="5"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="885"/>
            <end position="915"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="11">
        <location>
            <begin position="411"/>
            <end position="518"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="11">
        <location>
            <begin position="589"/>
            <end position="630"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="11">
        <location>
            <begin position="657"/>
            <end position="863"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="74"/>
            <end position="81"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00283"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000394"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50067"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="OBZ83535.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="915" mass="102948" checksum="7FE071882C3A272B" modified="2016-11-30" version="1">MSGNNIKVVCRFRPQNSLENREGGVPIIEIDDEGTNVQLKTVSKLTAINWCNRLVDNEYTDVTAGYNGTVFAYGQTGSGKTFTMMGADIDDENTKGIIPRIVEQIFTSINDAPSNLEFTVKVSYMEIYMEKVRDLFNPSADNLAIHEDKARGVYVKDLCEIYVANSDEVYTAMKNGSSNRVVAYTHMNAESSRSHSIVVITITQKNLDTGAAKAGKLYLVDLAGSEKVGKTGASGQTLEEAKKINKSLTALGMVINALTDGKSSHIPYRDSKLTRILQESLGGNSRTTLIINCSPSSFNEAETLSTLRFGMRAKTIKNKAKVNADLSPAELKALLKKVKSETITFQTYIAALEGEVTVWRGGKTLPEDKWVTMDKITKGEFSALPPASNFRASSVAEDASRPTTPSVVLEKDEREELLKRENELMDQIAEKETELANREKLLESLKEEVGYYKEQEALVTKENQQMTSELSELRLQLQKISYESKENAINVDSLKEANQELIAELEELKKNLSEVRLAHKDSSDSEKEKKKAQKLAQIMFKLDPSGEINEKERQIRESLNKIETEGHGSLSLEELVALRRDLADSKILLDQHTKTISDLTEEKESLEKKKAELDAKFSNLEQEYEEALDKTIAEEEVAAQKNADMEETISTLKSKLEAQFATKREEQQKEIEELKQEITQKTENLQKLTTAVSDLKDANEKLQNTLAEQPAQTQSGDLSEREKELERMRKSMAKELADFETMKKVLMRDLQTRCEKVVELEMSLDETREQYNNVLRASNNKAQQKKMAFLERNLEQLTNLVEQNSSLKKEVALAERKLIARNERIQSLESLLQDAQEKLINQNQKFEAQLQAVRERLEQARSQKSQSSMALNFGRVAKPLRGGGAVVENADNMPASPTEKRDKRNSWIPGFMGSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N3J9</accession>
    <name>A0A1C7N3J9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_08267</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000621">
        <property type="protein sequence ID" value="OBZ83683.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N3J9"/>
    <dbReference type="STRING" id="101091.A0A1C7N3J9"/>
    <dbReference type="InParanoid" id="A0A1C7N3J9"/>
    <dbReference type="OrthoDB" id="10252171at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="1">
        <location>
            <position position="75"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ83683.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="87" mass="9601" checksum="65FD53304B31A8F8" modified="2016-11-30" version="1">MPLLNSAFILPVSPPKTPILEDLTASMLIHHSLNPAFREKYRVGQELGSGGFGFVVVAQERETGIERAVKFIIRKKVPSSAWVIDTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N4F3</accession>
    <name>A0A1C7N4F3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_08022</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000582">
        <property type="protein sequence ID" value="OBZ83931.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N4F3"/>
    <dbReference type="STRING" id="101091.A0A1C7N4F3"/>
    <dbReference type="InParanoid" id="A0A1C7N4F3"/>
    <dbReference type="OrthoDB" id="2274659at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="20"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="396"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="446"/>
            <end position="522"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="672"/>
            <end position="771"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="546"/>
            <end position="573"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="411"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="423"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="446"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="466"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="492"/>
            <end position="503"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="505"/>
            <end position="515"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="673"/>
            <end position="687"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="694"/>
            <end position="740"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="759"/>
            <end position="771"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ83931.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="771" mass="87307" checksum="C58501D2F36F5FCD" modified="2016-11-30" version="1">MPTKPVDRKVKKGKKEKIIVEKSSSVSESPRDSPKVKVVQTKSKIVPLEERAEHKKKRKSFPRRVLSWSIAAYLGYYAFAGCGSPLDQNSEKPAVCGPIDALKLDANALFENKIYPYAYPIYMSKLHSYVSPAANKAMSYYEQYGIPAQTQLMDYYKLYGAPAQTRLIEYYDQHGKPMVNQASTRAKEIYQEKVAPSASLYMDQAKTVTEPHLEKMQLLAQQQWDNAPPHVKRAFHSTIKAIQDWYKQAESTDLVPILIEFYYKTVDFFQYQLWPAIQSNPLTYQIKSNYDQHAKAYVDLHLKPLWTKYNDHVHLDQLLAHLWAAVPQRPKAVSSSPSSLLKDQTVGYSIGQIKTPESAESASEAPVAITTTIAPIVKSVEEALPATPAPAIEQPIVPHQQDKEQTQEKVSTATSFATTHTSQKQAASTISNADIHHNDDIVQEKSISPDSTAGHHNNDQIIVSPTDKDVAPVPQKKQEVAEKKTIPPPQSPTHFDTNENQIVPQEEELKEEDDQVNLNKDQWVVPPVEQETIKEKIVKPVQEKVIEPVQHKIEEIKEKLHAKKEEKERKEIVDSVTKIMEEKAIEPVQNKSVEAIKEELKIEEVKEVVKESVKKSVKEAVSPKEINDKKEEETVEPEVAKPIEFDIKKPVEKVIKEPVQKILQKIHVVESMQEQHNEEESSKDAKESIAPVIADKKKETNPSLKKTEQKVFSDDKVPFKVDEHVSKDIPPATHEKREIVADENEDVEIVSDNKPVVSNEESQFVATEQTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N5V6</accession>
    <name>A0A1C7N5V6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="10">E3 ubiquitin-protein ligase COP1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">COP1</name>
        <name evidence="10" type="ORF">A0J61_07422</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000500">
        <property type="protein sequence ID" value="OBZ84523.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N5V6"/>
    <dbReference type="STRING" id="101091.A0A1C7N5V6"/>
    <dbReference type="InParanoid" id="A0A1C7N5V6"/>
    <dbReference type="OrthoDB" id="273771at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd16504">
        <property type="entry name" value="RING-HC_COP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042755">
        <property type="entry name" value="COP1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017907">
        <property type="entry name" value="Znf_RING_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44080">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE COP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13923">
        <property type="entry name" value="zf-C3HC4_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00518">
        <property type="entry name" value="ZF_RING_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 7" id="KW-0853">WD repeat</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 6" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="9">
        <location>
            <begin position="60"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="7">
        <location>
            <begin position="390"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="7">
        <location>
            <begin position="426"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="7">
        <location>
            <begin position="512"/>
            <end position="552"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="600"/>
            <end position="630"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="8"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="616"/>
            <end position="629"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OBZ84523.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="660" mass="76071" checksum="A668F39FF87F2DCA" modified="2016-11-30" version="1">MSQPDPNHQLEETTENRKKGNSRVWSLVPTFLTSLGARNNTQPCIQKEQELDRLDEELACPICQDIMKDVYVTSCGHSFCHACIAVHLENQSDCPLCRSRLNIHELYPNFQLNKLAECRIRILKEASTSQKENTLEKLIQQCKQDPTAFAKSLADLLDIQDIERVFETAIDQKKKEILDRELIQKDLLHHFLTLLNKRNAEALEQLIQERAFIREDVDYVENNDASRKRKLSELYDTEDDYSHNDLDHTYNDIKREISSSSSISLDNSHYQPMLNRMQDRFDDIQYMYHDILSKSSQSISKRRKLLTDLSSTLYDLTRYSQFKSLDTLYYADCTKTPSSIVSSIEFDRDQEFVAAGGVTKEIKLFDFNMMHHQDNQIHCPSRVMVCGHKVSCLSWSPYLKPQLASSDYEGTIDIWDVTTGQKTLILSEHKRRAWSVDISRANPTMVASGSDDSTVKVWSLTQNKAIYTLEQKGNVCCAKFALHNSQYLAVGSADHHISCYDLRYPTRPYRIYKGHKKAVSYVKWMNDNEIISASTDSTLKLWDRESGQCIRTFQGHQNEKNFVGLSVSEDWISCGSESNRLYAYHKQSTLPVATFKFPKQPINHPNIAEQKNKEETETEPEEEEEDDELPNFVSSVCWKHGTNKILAANSKGMIKVLEMK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N6D9</accession>
    <name>A0A1C7N6D9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">AB hydrolase-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">A0J61_07340</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000489">
        <property type="protein sequence ID" value="OBZ84607.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N6D9"/>
    <dbReference type="FunCoup" id="A0A1C7N6D9">
        <property type="interactions" value="52"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N6D9"/>
    <dbReference type="InParanoid" id="A0A1C7N6D9"/>
    <dbReference type="OrthoDB" id="9974421at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005811">
        <property type="term" value="C:lipid droplet"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004771">
        <property type="term" value="F:sterol ester esterase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016042">
        <property type="term" value="P:lipid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016125">
        <property type="term" value="P:sterol metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11005">
        <property type="entry name" value="LYSOSOMAL ACID LIPASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0442">Lipid degradation</keyword>
    <keyword evidence="2" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="4">
        <location>
            <begin position="123"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="451"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="453"/>
            <end position="463"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022963"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OBZ84607.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="474" mass="54270" checksum="13755C4978AE2930" modified="2016-11-30" version="1">MPRFIIHGIDSTIKTIFPWTKHTEQKAHVSPLEKAQSFEKMVKYWRNYNCEQHIVRTFDDYLLCVHRIPSVKPTASDYDTFIPNEAIYINTDKGNKIEVADNIGQFMKDKLPRDSSSGYRGKPVVLLHHGFLMSSEVWVSNTEEYSNLPFILARQGYDVWLGNSRGNKYSQYHVHLNPNHQPFWNFSINEFAMRDLPDTVDYILKETGAPSLTYIGFSQGTAQAFAGLSINSDLNKKVNLFIALAPATTPKGLKHPLIDAFVKATPTVIYLMFGRKTPLKVTLFWQRIISPPLFVKVIDACVLFLFDWKGKNISTSQKTVSYQHLYSLTSVKSLVHWFQIIRTGQFQMYDEMPSRLPYHTVNTVADHVPPRFPTHQIKTPIAIFYGGSDSLVDFNVLSADLPSPLAYVKSVEKWEHLDFLWAEGVEKIVYPDILKLLSHFNSHQSNLSPIENGFKKEGLKHNDMEEDSSSTTEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N6G4</accession>
    <name>A0A1C7N6G4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Bud site selection protein 6</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">BUD6_1</name>
        <name evidence="5" type="ORF">A0J61_09036</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000759">
        <property type="protein sequence ID" value="OBZ82914.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N6G4"/>
    <dbReference type="FunCoup" id="A0A1C7N6G4">
        <property type="interactions" value="73"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N6G4"/>
    <dbReference type="InParanoid" id="A0A1C7N6G4"/>
    <dbReference type="OrthoDB" id="783096at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051286">
        <property type="term" value="C:cell tip"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005519">
        <property type="term" value="F:cytoskeletal regulatory protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030010">
        <property type="term" value="P:establishment of cell polarity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.1540">
        <property type="entry name" value="Actin interacting protein 3, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022782">
        <property type="entry name" value="AIP3-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005613">
        <property type="entry name" value="AIP3_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056279">
        <property type="entry name" value="Aip3p_Bud6_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051825">
        <property type="entry name" value="SRCIN1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22741:SF10">
        <property type="entry name" value="COILED-COIL DOMAIN-CONTAINING PROTEIN CG32809"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22741">
        <property type="entry name" value="P140CAP/SNIP-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03915">
        <property type="entry name" value="AIP3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23153">
        <property type="entry name" value="Aip3p_Bud6_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00806">
        <property type="entry name" value="AIP3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Actin interacting protein 3 C-terminal" evidence="4">
        <location>
            <begin position="409"/>
            <end position="875"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="123"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="548"/>
            <end position="586"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="881"/>
            <end position="926"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="501"/>
            <end position="539"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="599"/>
            <end position="700"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="735"/>
            <end position="779"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="123"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="139"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="174"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="219"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="261"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="331"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="342"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="365"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="562"/>
            <end position="583"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="888"/>
            <end position="912"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OBZ82914.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="926" mass="104226" checksum="5CBE8F034A02F523" modified="2016-11-30" version="1">MRRTSSSVGMSGEIEQVVTKLLRTTKALLEALTQWSLMRASNSEIFEIHDTLEKQFFLVSQAFEEVNVNMSDLQWIPRQLRESVSVAMLETPSPAILDQYLPRIREVIVHLLHGLKGKQALLREKDKDREQPSRDSRASVRSTSTSESWNREVPLAALNRGSTSQRIMMYPSSPSSPPLQPHPPISPRMTPSGEYEPWSGGMPRPSVPTNDLSSRIMPRSNSASFNRSSSQQNSPKMSQQPLPTRSTSSSRSGQAHMLQPSVPPPPPPPAPPAPPVRAEPKPQPQQPQQFDESDPNTASALAALKRQENLARRSSVRRASMFRGNGGSSGGEYNNLSSSGSISRGKNPYSSSENKNIPPVPSLPASAQSSLKNTDQVGSVASSPLNSRLNTVSELKEVREEDNQGLTLFLQIGKEVKKVKYNGELSIPSLNMLFLEKFSYSNGQNDFPKIYIRDPTVGVSYELTDLSEVRDKSVLSFNINEKEEQQQSQKEWLTEVSNVFSKEVTETRRLLTEQMDELKKQLEASKSSDEEKEQQLIQQVTAHVLAQTKVQQTEEAPSEPSEIPEEAPTDEVELEKEESEEPTEQIATVTTTTITKEQFEAQRTEIEKLRRDIAVLRQLEREMREETSSTIQEMKEKAVAFKEAAKKAESAEVPVSAARASLEDGKKTLLQKSDKVTTRLEDLQDLIDQLKLDVTQRKCRPSETQMIHCANERKALSEEIEEFGQFITQVKPRWKKTWEQELQTIVKEQQTLKDQEYLLSDMRDDLDALLEVFEQLEKIYAYQASTKPQVREFRVVPAEDGFEGMASVMKQVSTIDVDHERRLRALEQADKMRQRELANRVDEFEKELVGFVGNNKLKKTGGALEIDRLRKQKEEEMLKAMYAEKRAANAANASPASTSSTEEPPSEQPQAEAETDENANKDSAEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N757</accession>
    <name>A0A1C7N757_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">thioredoxin-dependent peroxiredoxin</fullName>
            <ecNumber evidence="2">1.11.1.24</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">Prdx1_2</name>
        <name evidence="11" type="ORF">A0J61_06951</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>a hydroperoxide + [thioredoxin]-dithiol = an alcohol + [thioredoxin]-disulfide + H2O</text>
            <dbReference type="Rhea" id="RHEA:62620"/>
            <dbReference type="Rhea" id="RHEA-COMP:10698"/>
            <dbReference type="Rhea" id="RHEA-COMP:10700"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:30879"/>
            <dbReference type="ChEBI" id="CHEBI:35924"/>
            <dbReference type="ChEBI" id="CHEBI:50058"/>
            <dbReference type="EC" id="1.11.1.24"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.11.1.24" evidence="2"/>
    <dbReference type="EMBL" id="LUGH01000445">
        <property type="protein sequence ID" value="OBZ84995.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N757"/>
    <dbReference type="FunCoup" id="A0A1C7N757">
        <property type="interactions" value="531"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N757"/>
    <dbReference type="InParanoid" id="A0A1C7N757"/>
    <dbReference type="OrthoDB" id="185659at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008379">
        <property type="term" value="F:thioredoxin peroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045454">
        <property type="term" value="P:cell redox homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033554">
        <property type="term" value="P:cellular response to stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042744">
        <property type="term" value="P:hydrogen peroxide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006979">
        <property type="term" value="P:response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd03015">
        <property type="entry name" value="PRX_Typ2cys"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.30.10:FF:000003">
        <property type="entry name" value="Peroxiredoxin 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000866">
        <property type="entry name" value="AhpC/TSA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050217">
        <property type="entry name" value="Peroxiredoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024706">
        <property type="entry name" value="Peroxiredoxin_AhpC-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019479">
        <property type="entry name" value="Peroxiredoxin_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10681:SF171">
        <property type="entry name" value="PEROXIREDOXIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10681">
        <property type="entry name" value="THIOREDOXIN PEROXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10417">
        <property type="entry name" value="1-cysPrx_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00578">
        <property type="entry name" value="AhpC-TSA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000239">
        <property type="entry name" value="AHPC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0049">Antioxidant</keyword>
    <keyword evidence="6" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="7" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin" evidence="10">
        <location>
            <begin position="3"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="active site" description="Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity" evidence="9">
        <location>
            <position position="48"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="11">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009796"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00049091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR000239-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="OBZ84995.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="195" mass="21617" checksum="8F7AFA6CAD191773" modified="2016-11-30" version="1" fragment="single">IVAQVQKPAPAFTAPAVVNGEFKDISLSDYKGKYVVFFWYPMDFTFVCPTEILAFSERVKEFEALDTVVIGASTDSEFSHLAWINTPRKQGGLGEMNIPLLADKTKSIAKDYGVLIEEAGVALRGLFIIDPKGIVRQITINDLPVGRSVDEVLRLVEAFQFTDKHGEVCPANWKAGAKTIKPDVEKSKEYFNTVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-06-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N7T0</accession>
    <name>A0A1C7N7T0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_06848</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000433">
        <property type="protein sequence ID" value="OBZ85107.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N7T0"/>
    <dbReference type="InParanoid" id="A0A1C7N7T0"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ85107.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="78" mass="9253" checksum="8B3320347217BF3D" modified="2016-11-30" version="1">MRVFRTRRSPVIGEIGRPHLSYGRIIWVEKNYEHRVNPTNNVAANQTQCRWPQINQSRCWFSAERGLISAAYEKESEY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N7U0</accession>
    <name>A0A1C7N7U0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_06787</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000426">
        <property type="protein sequence ID" value="OBZ85162.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N7U0"/>
    <dbReference type="STRING" id="101091.A0A1C7N7U0"/>
    <dbReference type="InParanoid" id="A0A1C7N7U0"/>
    <dbReference type="OrthoDB" id="2266604at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008889532" evidence="2">
        <location>
            <begin position="18"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="151"/>
            <end position="172"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ85162.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="190" mass="19393" checksum="0E4E63278CFBBD72" modified="2016-11-30" version="1">MVKLALLVSTLVLAAEALVQSPSYQFNVTSPAPNAPYVASQILPCIYDVAANSTSDNLQLSITLVGSNYSAVMTGSADISLGFSFEKQISGATVYEHQFNYHIPANTTSGAYEVVFTDNVSQTNVSIPITIAAAPVTPSSSSLLPSASATSADSSSTASVFRPNPSSAASSTSSSKYVAGALAALVISAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N7X2</accession>
    <name>A0A1C7N7X2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Tripeptidyl-peptidase 2</fullName>
            <ecNumber evidence="3">3.4.14.10</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="primary">Tpp2</name>
        <name evidence="15" type="ORF">A0J61_06727</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Release of an N-terminal tripeptide from a polypeptide.</text>
            <dbReference type="EC" id="3.4.14.10"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the peptidase S8 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.14.10" evidence="3"/>
    <dbReference type="EMBL" id="LUGH01000420">
        <property type="protein sequence ID" value="OBZ85230.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N7X2"/>
    <dbReference type="FunCoup" id="A0A1C7N7X2">
        <property type="interactions" value="940"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N7X2"/>
    <dbReference type="InParanoid" id="A0A1C7N7X2"/>
    <dbReference type="OrthoDB" id="10256524at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004177">
        <property type="term" value="F:aminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008240">
        <property type="term" value="F:tripeptidyl-peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.200:FF:000003">
        <property type="entry name" value="Tripeptidyl peptidase 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.710">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.25.690">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.3170">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.200">
        <property type="entry name" value="Peptidase S8/S53 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000209">
        <property type="entry name" value="Peptidase_S8/S53_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036852">
        <property type="entry name" value="Peptidase_S8/S53_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022398">
        <property type="entry name" value="Peptidase_S8_His-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023828">
        <property type="entry name" value="Peptidase_S8_Ser-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050131">
        <property type="entry name" value="Peptidase_S8_subtilisin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015500">
        <property type="entry name" value="Peptidase_S8_subtilisin-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046939">
        <property type="entry name" value="TPPII_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048384">
        <property type="entry name" value="TPPII_GBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048383">
        <property type="entry name" value="TPPII_Ig-like-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022229">
        <property type="entry name" value="TPPII_Ig-like-2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046940">
        <property type="entry name" value="TPPII_Ig-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43806">
        <property type="entry name" value="PEPTIDASE S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43806:SF14">
        <property type="entry name" value="TRIPEPTIDYL-PEPTIDASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00082">
        <property type="entry name" value="Peptidase_S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12580">
        <property type="entry name" value="TPPII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21316">
        <property type="entry name" value="TPPII_GBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21223">
        <property type="entry name" value="TPPII_Ig-like-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00723">
        <property type="entry name" value="SUBTILISIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52743">
        <property type="entry name" value="Subtilisin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51892">
        <property type="entry name" value="SUBTILASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00137">
        <property type="entry name" value="SUBTILASE_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00138">
        <property type="entry name" value="SUBTILASE_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0031">Aminopeptidase</keyword>
    <keyword evidence="10" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6 9" id="KW-0645">Protease</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 9" id="KW-0720">Serine protease</keyword>
    <feature type="domain" description="Peptidase S8/S53" evidence="11">
        <location>
            <begin position="37"/>
            <end position="488"/>
        </location>
    </feature>
    <feature type="domain" description="Tripeptidyl-peptidase II first Ig-like" evidence="13">
        <location>
            <begin position="522"/>
            <end position="643"/>
        </location>
    </feature>
    <feature type="domain" description="Tripeptidyl-peptidase II galactose-binding" evidence="14">
        <location>
            <begin position="660"/>
            <end position="759"/>
        </location>
    </feature>
    <feature type="domain" description="Tripeptidyl peptidase II second Ig-like" evidence="12">
        <location>
            <begin position="799"/>
            <end position="987"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="10">
        <location>
            <begin position="144"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="10">
        <location>
            <begin position="1020"/>
            <end position="1070"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="9">
        <location>
            <position position="46"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="9">
        <location>
            <position position="265"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="9">
        <location>
            <position position="451"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00020244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF12580"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF21223"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF21316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="OBZ85230.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="1277" mass="141427" checksum="5D37CE0D91F27231" modified="2016-11-30" version="1">MTIAAIKPISEYPVHGLMPKQDTQAASFIKKFPEYDGRGTVIAILDTGVDPGAAGMQVTTDGKPKMIDIVDCTGGGDVETTKVVKPTSKDGNNVIKGLSGRDLILDDSWKNPSGEYRVGLKRAYELFPGDLISRIKSERCQNHNKKHAHLLSEAQARLAEYQSKKDKEDAELSELEARVEALKELQNNFEDPGLLFDCVVFFDGKDWRAVIDVNESGDLRGQPCLTDYRKELQYHTFGEADLLNFSVNIYADGDVLSIVTLAGSHGTHVAGIAAGNFPDEPALNGVAPGAQIVSLRIGDSRLGSMETGPGLTRAAAHLAINKVDLANMSYGESSSLATDGHFINLLANEAIGKAGCIFVTSAGNDGPCFSSIGAPAGMDASFITVGAYVKHAQMQAEYALLESVTERPYTWSSRGPTTDGYHGVDIYAPGSAITSIPVYVLNKLDLKNGTSMSSPNACGCIALLVSALKAQKIDYTPYRVKNAVVQTGKSVDDPLDVGFIQVDKAWEYLESYKDRKDLDILYRVSVNKRGTQRGVYLRELDEVSQIQYLAATIVPSFMNEEDYENPKYNKAKFNYDVRVALVATESWISAPDYLYLGSHGNSFQLKVDPTALSESKFHFGQVLGYDTSAPERGPLFRIPVSVVKPIVSSKGSIQFKNVEYGPGDIVRRFVHVPEGATNCELVIKATSPNNDTSPARFMLHLLQLVPQQSQKKKHAYSFAIGSGSYGHSSSDEQIVKKRFSVRGGLNLEVCLAQFWSSLGKHNIDLSLHFHGVQIAGQAVSSQDVVRLEPQVTRLDISSPVRREDNLKVSVSFDKLRKYIRPAEATISPMRPDRDTLPSTCLMYQLILTYKFKIESFTNMVARFPTVMNRLYEHFLAGMFGIVYDYNQKVVGYLDVFDQNIKLNQKGDYTIMLQLSTEKESVLEKLKETILELDLDLKSTSFNTFRKMADVYTQSSSNYSKIALERKDIRALYIAAPTEKDAIPKDAKPGDVLVGKLNFFGKVDGGEYTALYTVPPASIEAKKEKKDKKSTDEELQQQLKDATRDLQISYLKKFAADSSAYKEQLAQLEASFPDDIAALEYKLDAIWKASEAKDSTGCLLKSGQLSTSQAQEISQIADKIISKIDERELLEFYGRKKSEDETDEQKEKRKQNDVKKKQLINALENKAMAQAAVLDNSKIEDLSNIINSLEQWGANGSSLKSVLVKVKRDREEGHLGKALKSIESYLADASINSDNASDVSKAWTVRNELLKELKWNLWAKYDDKWSMIRQPPYGLALF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N7Z5</accession>
    <name>A0A1C7N7Z5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_06753</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000423">
        <property type="protein sequence ID" value="OBZ85191.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N7Z5"/>
    <dbReference type="InParanoid" id="A0A1C7N7Z5"/>
    <dbReference type="OrthoDB" id="2269207at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.140.150">
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="131"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="164"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="293"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="489"/>
            <end position="508"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="293"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="312"/>
            <end position="329"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ85191.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="523" mass="57947" checksum="50EF46BD5C704260" modified="2016-11-30" version="1">MNFCDTMSSIWLSSLLCFSITFLLCLAIGISSWLETNDHMLSSTPLLSEHLSLFKVHLYSIKNNRIIYLTFGLWRYCIIDRQSNTNACSQASINFEIDTNKMTEIISKINDSVSLNKNDLLPLSAVSHVRFVLLLLASLGAVTSLITISFLIPGKTRRNWQRRVLFRLVSLKSLIGATLTSVALGVSLRNYRTNISSLCSNLSINQNGYICQSYTSSTETISLAVSIGLFVVCAIHSAACSFAQPSPPVPSTSRANNSVASLFVEDSITSEKVPSQAINEDAYDSYMEKLESHYNNSTSASNRASLRPPPQRQRSVRINNHETPTTEPGVQNPVHLEPEKESREIPLPTSIRQSVDITSANILMPPAPPFANGNNRPSFCLDYRPPSYGSNHTFGALQANYFGTDDSSQTSSCIDRIHKTDSTGPGSSHLMYDSSSAAMQSNHTLGVDFTSNHPNINRNSSSFRCHNNSSFSGEEDVIDLYYSTDDSSNVRSSIPPSQPISNYSQNNDDLYKRIDDYRQFKDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N844</accession>
    <name>A0A1C7N844_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Protein phosphatase</fullName>
            <ecNumber evidence="1">3.1.3.16</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_06824</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>O-phospho-L-seryl-[protein] + H2O = L-seryl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:20629"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="EC" id="3.1.3.16"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:47004"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="EC" id="3.1.3.16"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the PP2C family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.16" evidence="1"/>
    <dbReference type="EMBL" id="LUGH01000430">
        <property type="protein sequence ID" value="OBZ85128.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N844"/>
    <dbReference type="STRING" id="101091.A0A1C7N844"/>
    <dbReference type="InParanoid" id="A0A1C7N844"/>
    <dbReference type="OrthoDB" id="60843at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004722">
        <property type="term" value="F:protein serine/threonine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.40.10">
        <property type="entry name" value="PPM-type phosphatase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036457">
        <property type="entry name" value="PPM-type-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001932">
        <property type="entry name" value="PPM-type_phosphatase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039123">
        <property type="entry name" value="PPTC7"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12320:SF84">
        <property type="entry name" value="PROTEIN PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12320">
        <property type="entry name" value="PROTEIN PHOSPHATASE 2C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07228">
        <property type="entry name" value="SpoIIE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00331">
        <property type="entry name" value="PP2C_SIG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00332">
        <property type="entry name" value="PP2Cc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81606">
        <property type="entry name" value="PP2C-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51746">
        <property type="entry name" value="PPM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0460">Magnesium</keyword>
    <keyword evidence="1" id="KW-0464">Manganese</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1" id="KW-0904">Protein phosphatase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PPM-type phosphatase" evidence="2">
        <location>
            <begin position="144"/>
            <end position="401"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU366020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51746"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ85128.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="418" mass="47142" checksum="B22B96533301F809" modified="2016-11-30" version="1">MKSKAWLTVSSTARQMSQHQHSFVHQQSLPTLSCIRSHLSTGISIDNKEETERSDYHYPPMPSAKIKRDDIRILANAATARYYPIYTHPSRRLQHTLLPYPDHHRPSPSLPLLDFFSQSKSSPSYIFAHGASGFAKRQRYTTPDMHKYNNEHYYSIQIGEDAYFRRSDAMGVADGVGGWSGVSAANAALYSRKLMHHAYLQLERFNNRDDPYYYHYDDADPMRILQKSYEESMQEAQQEGIIGSCTACLAILRHQELRIANIGDCGISVIRQNNYIFRSEEQQHAFNFPYQLGTSSPDRPKDAQSFTVAVEKGDIIIMGSDGLFDNLFDKEILSIVRSLVSKKRITSIEPQTISDALAERAKAVSHSKINVDSPFQARAVSEGLYYQGGKVDDISVLVAIVKDGSPNHVSLSSSNTHI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N898</accession>
    <name>A0A1C7N898_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Phosphatidylglycerophosphatase GEP4, mitochondrial</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">GEP4</name>
        <name evidence="1" type="ORF">A0J61_06664</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000413">
        <property type="protein sequence ID" value="OBZ85287.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N898"/>
    <dbReference type="FunCoup" id="A0A1C7N898">
        <property type="interactions" value="253"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N898"/>
    <dbReference type="InParanoid" id="A0A1C7N898"/>
    <dbReference type="OrthoDB" id="198652at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008962">
        <property type="term" value="F:phosphatidylglycerophosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027706">
        <property type="entry name" value="PGP_Pase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010021">
        <property type="entry name" value="PGPP1/Gep4"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01668">
        <property type="entry name" value="YqeG_hyp_ppase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19288">
        <property type="entry name" value="4-NITROPHENYLPHOSPHATASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19288:SF25">
        <property type="entry name" value="PHOSPHATIDYLGLYCEROPHOSPHATASE GEP4, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09419">
        <property type="entry name" value="PGP_phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ85287.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="212" mass="23506" checksum="92CD73C3E7993FFB" modified="2016-11-30" version="1">MVQSLNLSGIVNAFRVLWNPSLAMPHVIVEGKSLLYRKKVSDNLSASPKKDIRQINFANLKRLGQIKAIGFDKDNCLTAPYVSTIHPPFQEAWEECKSTFSKENVVIVSNSAGTADDKDGREAAKLEESLDVTVLRHQEKKPSGGKALADHMAPLPAHQIAFVGDRILTDVLFGNLNGNLTIWTRQVVTEQGDNKPAMMVKLYRLMSLYMGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N8Q6</accession>
    <name>A0A1C7N8Q6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">3'-5' exonuclease domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_06464</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000391">
        <property type="protein sequence ID" value="OBZ85483.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N8Q6"/>
    <dbReference type="STRING" id="101091.A0A1C7N8Q6"/>
    <dbReference type="InParanoid" id="A0A1C7N8Q6"/>
    <dbReference type="OrthoDB" id="26838at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008408">
        <property type="term" value="F:3'-5' exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006139">
        <property type="term" value="P:nucleobase-containing compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002562">
        <property type="entry name" value="3'-5'_exonuclease_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01612">
        <property type="entry name" value="DNA_pol_A_exo1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="3'-5' exonuclease" evidence="1">
        <location>
            <begin position="105"/>
            <end position="218"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01612"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ85483.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="237" mass="27067" checksum="ECC6E9619CCB3666" modified="2016-11-30" version="1">MEESSSQYWNNVLKSADLLLSLLTPYEDKEDIDLVQNVLPPLRQLVKKGSSYSIPKQVIPAQPKQEHNSTPRRHRVSYEQEKNWKRINNNNIHITLSSGRVVNCIVVNTPEGLEKVIESIKQAEYVTFDCEFMGLKNAIPELKLLQIAVSDICGYAIQVDILGRHILEQKLKPVMESKDVTWIGWALRSDMLSIEQFFGALKDTGILDLQKKLATYAVEELNLHAAMAKYASDWDVW</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N8Y0</accession>
    <name>A0A1C7N8Y0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">peptidylprolyl isomerase</fullName>
            <ecNumber evidence="4">5.2.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">cyp12</name>
        <name evidence="12" type="ORF">A0J61_06358</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 14">
            <text>[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)</text>
            <dbReference type="Rhea" id="RHEA:16237"/>
            <dbReference type="Rhea" id="RHEA-COMP:10747"/>
            <dbReference type="Rhea" id="RHEA-COMP:10748"/>
            <dbReference type="ChEBI" id="CHEBI:83833"/>
            <dbReference type="ChEBI" id="CHEBI:83834"/>
            <dbReference type="EC" id="5.2.1.8"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the cyclophilin-type PPIase family. PPIase D subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.2.1.8" evidence="4"/>
    <dbReference type="EMBL" id="LUGH01000381">
        <property type="protein sequence ID" value="OBZ85583.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N8Y0"/>
    <dbReference type="FunCoup" id="A0A1C7N8Y0">
        <property type="interactions" value="719"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N8Y0"/>
    <dbReference type="InParanoid" id="A0A1C7N8Y0"/>
    <dbReference type="OrthoDB" id="407558at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016018">
        <property type="term" value="F:cyclosporin A binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042026">
        <property type="term" value="P:protein refolding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd01926">
        <property type="entry name" value="cyclophilin_ABH_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.10:FF:000029">
        <property type="entry name" value="peptidyl-prolyl cis-trans isomerase D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.100.10:FF:000009">
        <property type="entry name" value="Peptidyl-prolyl cis-trans isomerase D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.100.10">
        <property type="entry name" value="Cyclophilin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029000">
        <property type="entry name" value="Cyclophilin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020892">
        <property type="entry name" value="Cyclophilin-type_PPIase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002130">
        <property type="entry name" value="Cyclophilin-type_PPIase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11071">
        <property type="entry name" value="PEPTIDYL-PROLYL CIS-TRANS ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11071:SF561">
        <property type="entry name" value="PEPTIDYL-PROLYL CIS-TRANS ISOMERASE D-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00160">
        <property type="entry name" value="Pro_isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13181">
        <property type="entry name" value="TPR_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00153">
        <property type="entry name" value="CSAPPISMRASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50891">
        <property type="entry name" value="Cyclophilin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00170">
        <property type="entry name" value="CSA_PPIASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50072">
        <property type="entry name" value="CSA_PPIASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9 12" id="KW-0413">Isomerase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0677">Repeat</keyword>
    <keyword evidence="8" id="KW-0697">Rotamase</keyword>
    <keyword evidence="7 10" id="KW-0802">TPR repeat</keyword>
    <feature type="domain" description="PPIase cyclophilin-type" evidence="11">
        <location>
            <begin position="7"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="10">
        <location>
            <begin position="301"/>
            <end position="334"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="OBZ85583.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="364" mass="40197" checksum="63B6FF88722EF491" modified="2016-11-30" version="1">MANPRVYFDVTIGGKPEGRIVFELYKDVVPKTAENFRALCTGEKGVGQSGKPLHYKGSIFHRIIKDFMIQGGDFTAGNGTGGESIYGEKFEDENFEYKHDKPFLLSMANAGPGTNGSQFFITTVPTPHLDGKHVVFGKVLKGKGVVRALEALETVQDKPLEDAVIANCGELAEGEDDGIVVNADGDNYEEFPDDHEGPKELTDIVEIAGKLKDIGNDYFKKGDHQNASKKYTKAVRYLNFKPAFDEEDPEGLRVKYNAVKVPCFLNKAMCALKLGEYSECIKATTNVIHFDAKYLKKTDITKAYYRRGVAKANSKDLEGAVEDLQKASEQDPEDAGIKKELANTKAKLIAKKKKEKDAYAKLFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N8Y6</accession>
    <name>A0A1C7N8Y6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Polyadenylate-binding protein</fullName>
            <shortName evidence="13">PABP</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="primary">pab1_1</name>
        <name evidence="17" type="ORF">A0J61_06860</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">Binds the poly(A) tail of mRNA.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 13">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 13">Belongs to the polyadenylate-binding protein type-1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000434">
        <property type="protein sequence ID" value="OBZ85089.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N8Y6"/>
    <dbReference type="FunCoup" id="A0A1C7N8Y6">
        <property type="interactions" value="458"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N8Y6"/>
    <dbReference type="InParanoid" id="A0A1C7N8Y6"/>
    <dbReference type="OrthoDB" id="19742at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051028">
        <property type="term" value="P:mRNA transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006417">
        <property type="term" value="P:regulation of translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd12378">
        <property type="entry name" value="RRM1_I_PABPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd12379">
        <property type="entry name" value="RRM2_I_PABPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd12380">
        <property type="entry name" value="RRM3_I_PABPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd12381">
        <property type="entry name" value="RRM4_I_PABPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1900.10:FF:000004">
        <property type="entry name" value="Polyadenylate-binding protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.330:FF:000003">
        <property type="entry name" value="Polyadenylate-binding protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.330:FF:000441">
        <property type="entry name" value="Polyadenylate-binding protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.330:FF:000520">
        <property type="entry name" value="Polyadenylate-binding protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.330:FF:000648">
        <property type="entry name" value="Polyadenylate-binding protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1900.10">
        <property type="entry name" value="c-terminal domain of poly(a) binding protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036053">
        <property type="entry name" value="PABP-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006515">
        <property type="entry name" value="PABP_1234"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002004">
        <property type="entry name" value="PABP_HYD_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034364">
        <property type="entry name" value="PABP_RRM1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045305">
        <property type="entry name" value="RRM2_I_PABPs"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003954">
        <property type="entry name" value="RRM_euk-type"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01628">
        <property type="entry name" value="PABP-1234"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24012">
        <property type="entry name" value="RNA BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00658">
        <property type="entry name" value="MLLE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00517">
        <property type="entry name" value="PolyA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00361">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63570">
        <property type="entry name" value="PABC (PABP) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51309">
        <property type="entry name" value="PABC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 13" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="8" id="KW-0509">mRNA transport</keyword>
    <keyword evidence="11" id="KW-0539">Nucleus</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0677">Repeat</keyword>
    <keyword evidence="10 12 13" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="9" id="KW-0810">Translation regulation</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="domain" description="RRM" evidence="15">
        <location>
            <begin position="45"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="15">
        <location>
            <begin position="133"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="15">
        <location>
            <begin position="226"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="15">
        <location>
            <begin position="330"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="domain" description="PABC" evidence="16">
        <location>
            <begin position="533"/>
            <end position="610"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="464"/>
            <end position="530"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="14">
        <location>
            <begin position="474"/>
            <end position="512"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="14">
        <location>
            <begin position="521"/>
            <end position="530"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022816"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022845"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU362004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS51309"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="OBZ85089.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="620" mass="68410" checksum="3D755EE4594D7156" modified="2016-11-30" version="1">MSTSPVVTPAEVAPVQQLSAEQQQQIAQAQASAPAGSAVAPSPSASLYVGELDPSVTEAMLFEMFNMIGPVASIRVCRDAVTRRSLGYAYVNFHNIVDGERALESLNYTLIKGKPCRIMWSQRDPSLRKTGSGNVFIKNLDQTIDNKALHDTFSAFGNILSCKIAIDESGNSKGYGFVHYETEEAADNAIKHVNGMLLNDKKVYVGRHIPKKERQAKIEQYRAKFTNVYVKNLDESVSDEQLKEMFGKYGPITSAVIQVDEEGKSKGFGFVNFEDHEDAQKAVDALNETEQSEGKILYVARAQKKSEREEELRKQYEQAKLEKLAKYQGVNLYVKNLDDDLDDEKLRQEFSVYGVITSAKVMTDEKGQSKGFGFVCFSSPDEATKAVTEMNGRMIGSKPIYVALAQRKEVRRSQLEAQMAQRNQMRMQQGMPMPGAPGYMPGAPMFYAPPGGFLPQGQRPVFPPNGMMPRPRWAPQQGQPMPGFPPQGFAPNNNMRPPRQPRAPRGGAAGQRKYANQARQNPAQEASAETAANAPLTAAALAAAPAEAQKQMLGERLYPLINAQQPEYAGKITGMLLEMDNGELLNLLEDNKALDSKINEAMEVLKAHMSEAPKEEEKEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N907</accession>
    <name>A0A1C7N907_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_06843</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000433">
        <property type="protein sequence ID" value="OBZ85109.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N907"/>
    <dbReference type="STRING" id="101091.A0A1C7N907"/>
    <dbReference type="InParanoid" id="A0A1C7N907"/>
    <dbReference type="OrthoDB" id="2281978at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="18"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="287"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="28"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="46"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="75"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="91"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="103"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="287"/>
            <end position="310"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ85109.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="331" mass="38913" checksum="CD606D8DA382929B" modified="2016-11-30" version="1">MSIDNLAIDFNNHVSLELKVPTSEPMKHHALQKHDRKTRNRQIVPSDDEEEEDEDEDEDDDSDTESKSKPSKITLRSKHPKQIKKSQPLPSDDEEEEEEDELIRENEGQLGERYKNMATYDQDDDVPLYYNTNNGFQQDMYDDEDDNRALVPENPNAGPMLNFVEGSHLQHLHYQQQYHQAQLAQFQYMQQQQQHRGHRASYQPFYNQQNKSMSGMDLLKQLEQEKADAKRVKPKIDTSNVKIEGLLSRLPEPGSHNISFQQLEQQQRKKASHQPRPLSAHAMYYDPYQQQQQQFYNQQQLQIPQQQYYPPRSPSPSHIKPNHSSGNKRHK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-06-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N9Q9</accession>
    <name>A0A1C7N9Q9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_07859</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000557">
        <property type="protein sequence ID" value="OBZ84084.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N9Q9"/>
    <dbReference type="InParanoid" id="A0A1C7N9Q9"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ84084.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="84" mass="9695" checksum="F35BC957F2B00B28" modified="2016-11-30" version="1">MTELFYYLPLCYTQGACYELFNQHNKDILLLAPTSSLIDEKPNSCLSASDVYRLRKVIKSNIYTETLTRSQARLAAILRFKQAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N9V3</accession>
    <name>A0A1C7N9V3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_06028</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000345">
        <property type="protein sequence ID" value="OBZ85912.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N9V3"/>
    <dbReference type="InParanoid" id="A0A1C7N9V3"/>
    <dbReference type="OrthoDB" id="2274679at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="314"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="340"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="360"/>
            <end position="375"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ85912.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="375" mass="41813" checksum="5AA33723A8C4DA73" modified="2016-11-30" version="1">MSGNSNFAYEIRFVEDNVVQIYDIAAKRKQQDSENLLPTEYKEEDVVEGKLRYSKLVGSTRSNGPKDMFGLEDNGQPYQHHVVTKISKNRKSTQRNTFFMMGGAGGGSSSYDFDDTQVGASVAESISYYGHLDKEKQNISPASPIKTQFEINSLNSIVQPSMHSPVHSPIHSPIQSPIHSPIHSPIHSPIHSPIHSPIHSPIHSALYSSMQESLSSAFCLKTDSSLYLSDSLPDIDQLETDASSMHHIHTQSNTHVDSQIDNTTYTRSHLLSVSSNRMIMPIAESDLSPTETIQTEQETTKSIQPPPKIVTRTSIRHKEEEYLSEKSSLPAPKYEAENYTELSINESISNDSTRHIQQSSEKKPPSDKRSCCIIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NAB4</accession>
    <name>A0A1C7NAB4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_05993</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000342">
        <property type="protein sequence ID" value="OBZ85960.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NAB4"/>
    <dbReference type="InParanoid" id="A0A1C7NAB4"/>
    <dbReference type="OrthoDB" id="2290541at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="195"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="282"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="197"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="245"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="290"/>
            <end position="300"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ85960.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="307" mass="34965" checksum="63A64CE1A543264A" modified="2016-11-30" version="1">MSTVKIIVTPEKQQASVSFQMLSEKLNWDNLTQLIQSSTFAAPPFMLYYRYGRDIETLDSQTQLTQLLSTLGSVSLLRLYGYKDNQLLPVTIPSKTALFHRLGVLVEDSRLTIESDHLVRWIGLFASSLASQDDKDFDVEFQMLEQIIQGHREKAALVHEEKEALDKTLSEQEEELFGLLQSFGLSDKQHGPFGHGIGHHRRFPHFHGSRKHGHPRGPPPAHEPPHGPHGSHRFHGPFGSFGPDFNDRPFPHGEPDLFSGPGLFNITPPMFSYGNIHHHYDFGPNEKDRKKGKHHRHHHPYMSSEEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NAB5</accession>
    <name>A0A1C7NAB5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">A0J61_05893</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000333">
        <property type="protein sequence ID" value="OBZ86053.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="FunCoup" id="A0A1C7NAB5">
        <property type="interactions" value="4"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NAB5"/>
    <dbReference type="InParanoid" id="A0A1C7NAB5"/>
    <dbReference type="OrthoDB" id="68020at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000127">
        <property type="term" value="C:transcription factor TFIIIC complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042791">
        <property type="term" value="P:5S class rRNA transcription by RNA polymerase III"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006384">
        <property type="term" value="P:transcription initiation at RNA polymerase III promoter"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046488">
        <property type="entry name" value="Sfc3/Tfc3_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044210">
        <property type="entry name" value="Tfc3-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007309">
        <property type="entry name" value="TFIIIC_Bblock-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15180">
        <property type="entry name" value="GENERAL TRANSCRIPTION FACTOR 3C POLYPEPTIDE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15180:SF1">
        <property type="entry name" value="GENERAL TRANSCRIPTION FACTOR 3C POLYPEPTIDE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04182">
        <property type="entry name" value="B-block_TFIIIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20222">
        <property type="entry name" value="DUF6581"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <feature type="domain" description="B-block binding subunit of TFIIIC" evidence="7">
        <location>
            <begin position="126"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="domain" description="Transcription factor tau subunit sfc3/Tfc3 C-terminal" evidence="8">
        <location>
            <begin position="1029"/>
            <end position="1338"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="455"/>
            <end position="521"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="478"/>
            <end position="491"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="499"/>
            <end position="508"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF04182"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF20222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OBZ86053.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="1579" mass="181842" checksum="F0EFE07FC15D2966" modified="2016-11-30" version="1" fragment="single">FEKVFMLDQILAGLVEEVALEGESGCTLSQFFTLIENFAKKKCEQLDLKKPILFDEKYNSFLWELIKSDENLIFSKNKENLNVSSLGYEKLTSDADFVYVHAVEEVQDQVLYGNLKSEKKTLTAAHRQVLSVVAKCRSQGVSQFQLRELLGMDGKTVFRYIKKLDELGLVVKEEAYANNIITRIVFHRRFATDPSTNEETGSKQIENGVIYRIPDFKHDILEQLKKSPNSMMGMLELIKSLGLESQKQIRWARVRLTELHDQGLVERLIASDGKHKRHVVRLIEQSAKNNDDERQADTVHREEPKQSYCIHRDLPTEYVFYRDLVAAGDHGLTRQVRIIYDFVCDHCIHLSFFLKDLLNKYSMLDHVIPLSFFENGTIPSKDPALLKYLIYRTEELEGKQRQFRYFSSETWQNICSRMGKEAPSVPEPELPAFDDLVEPDRVDAIGFQIQQLFSSGKKRASGTPLKKETKRQKKSNKQEQTANKMDSQLAPSQPPTRKRTQEDIRASEEIENEPVNSKQVRTSIRDVKKFKKTSLDTTKARRCTIMLELVEKYRICELGQDIYREFIDIEAVQNTTKIARSTFDKLVAQMHKDKQLRLFVTSVQRPSGLTEIKKIILHKDLTEESESVKQYVNNFSVERSIVSSKNKVREIQKINVDALPPSATSLPRSQIKMDEIESPRKLASKYGYIRSIWQRARSFHEALFNFCSSHHTDTIDMAEFMKTLPFERILNLVIIPYDDNTLIEFLKDSSNRSIVMQHLPKEIRSIIYQAHRKLRTILVRLIHILEALELLKPAQEEKEITSCQQTKYKYIHTSYVLCRLAHVKIYARKDAPIKQTIRLNTFADLQQFWSELKVFNTSGFEKVDNDMNESHPLLNIWSPYTWTSGLWFTLEQKNVLDSYIDFQNKKVPSESDSTIRAYLMKKLNISTHRIKTYYDSIRNAFDKSTRREKKAKKKSSHISSSPAINELMKASLEKRKVNAALFKMRQTGPFVEQTFVGSRKLRRLRLVSEPYRGQDKIGKTRLRKPVAAYSRVEEDALVYAYSIMKARASTSTFYWGPIAKVLPAHTPERSRRVLSHMMKKDSKLSSTIEELKKHWLDIYEKGIACNEIQDEKPWDTQDYDLPSYLAYFVEKLQAAENAKRIAFLSEASPLPKAYADVHTWFNVFRKQDSSVKAFDSIDEIHATESLRSETFDAIDTTSFLGDEEASIACVSSLIKMILVTPESTYCAKDAFHMLKEFSESTIEKGISKLRSDGLIVGEKAKYGRVPGRNINVSEKFLNIAAGLLPYEFFKTARQYHKLLELKGSIDIQNSELNSGRMATVLDLLSQGKLIISLKDKDQFVESKKVLHYPKASAVSIRETFVYEKLDIKIQADLHTEPVARITTSEQVYIPTIEEIKATLESLALKQPIVHDLYNFITGHRKRGATRNEISSALNETYENVSDALDLLLNAKPALIRIFGLENLRYVSAEFCSHWMLKNPQNGQYMPPLMWYDASGGLTKPALEGCEDTVMSHILYTPGISFTQLHKRLQPLFSGFELHSILRTLITKQKSTVQLASDTSFGTSSQEATYYWLAPNYYLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NAH5</accession>
    <name>A0A1C7NAH5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Cyclin-L1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">ccnl1</name>
        <name evidence="2" type="ORF">A0J61_06326</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000377">
        <property type="protein sequence ID" value="OBZ85626.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NAH5"/>
    <dbReference type="FunCoup" id="A0A1C7NAH5">
        <property type="interactions" value="244"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NAH5"/>
    <dbReference type="InParanoid" id="A0A1C7NAH5"/>
    <dbReference type="OrthoDB" id="10264655at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016538">
        <property type="term" value="F:cyclin-dependent protein serine/threonine kinase regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.10">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013763">
        <property type="entry name" value="Cyclin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036915">
        <property type="entry name" value="Cyclin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043198">
        <property type="entry name" value="Cyclin/Ssn8"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10026">
        <property type="entry name" value="CYCLIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036580">
        <property type="entry name" value="Cyclin_L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00385">
        <property type="entry name" value="CYCLIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47954">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cyclin-like" evidence="1">
        <location>
            <begin position="108"/>
            <end position="194"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00385"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ85626.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="215" mass="24667" checksum="EC151E4878CF4912" modified="2016-11-30" version="1">MSVALKNPLASLEQLEVTISRRDGISEELEEDLRHLGAELIQSAGILLKLPQVAMATAQVLFQRFFYMASLKEFGIVKAYTMKDMAIAAEMQILRKLGFIVHVQLPYNLMINYLRILGLEEHRAITRRAWNYLNDGLRTTIYVTHEPSTIACAAIWLACLEESVKLPTDLGKEWWLLFDVDSVHFKNAAAHIKRLYYRKLDKANLPLYKLSNEQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NAI4</accession>
    <name>A0A1C7NAI4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_05825</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000326">
        <property type="protein sequence ID" value="OBZ86132.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NAI4"/>
    <dbReference type="STRING" id="101091.A0A1C7NAI4"/>
    <dbReference type="InParanoid" id="A0A1C7NAI4"/>
    <dbReference type="OrthoDB" id="10008801at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="129"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="129"/>
            <end position="140"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ86132.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="158" mass="18320" checksum="E51DC8BBDD72DA8E" modified="2016-11-30" version="1">MYYLFARQSFRLIARQTQCVPIRRMPARLIHTTRPTLAVSQDWQNRPKHPLIDKIEQHPHILQQLIDFTQLLQSKGVDVSGQQPSFMQMMKVMNDEEVKEKVKQLVQDMQAAGIQLDMNTIQELQASFMQPSTENESEGQSRGRKRGVLNSVKGLFKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NAP0</accession>
    <name>A0A1C7NAP0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">SH3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">A0J61_06252</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000369">
        <property type="protein sequence ID" value="OBZ85696.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NAP0"/>
    <dbReference type="STRING" id="101091.A0A1C7NAP0"/>
    <dbReference type="InParanoid" id="A0A1C7NAP0"/>
    <dbReference type="OrthoDB" id="196165at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051286">
        <property type="term" value="C:cell tip"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015630">
        <property type="term" value="C:microtubule cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030950">
        <property type="term" value="P:establishment or maintenance of actin cytoskeleton polarity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008104">
        <property type="term" value="P:intracellular protein localization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.40">
        <property type="entry name" value="SH3 Domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053039">
        <property type="entry name" value="Polarity_Bud-Selection_Reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000159">
        <property type="entry name" value="RA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036028">
        <property type="entry name" value="SH3-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001452">
        <property type="entry name" value="SH3_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47775">
        <property type="entry name" value="BUD SITE SELECTION PROTEIN 14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47775:SF1">
        <property type="entry name" value="BUD SITE SELECTION PROTEIN 14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00788">
        <property type="entry name" value="RA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00018">
        <property type="entry name" value="SH3_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00326">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50044">
        <property type="entry name" value="SH3-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50002">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0728">SH3 domain</keyword>
    <feature type="domain" description="SH3" evidence="4">
        <location>
            <begin position="40"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="511"/>
            <end position="578"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="648"/>
            <end position="685"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="704"/>
            <end position="731"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="758"/>
            <end position="805"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="897"/>
            <end position="1000"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="9"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="24"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="541"/>
            <end position="561"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="566"/>
            <end position="578"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="649"/>
            <end position="661"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="664"/>
            <end position="677"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="704"/>
            <end position="715"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="719"/>
            <end position="731"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="768"/>
            <end position="783"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="786"/>
            <end position="805"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="915"/>
            <end position="924"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="944"/>
            <end position="978"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="991"/>
            <end position="1000"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OBZ85696.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="1032" mass="115667" checksum="FE60F5B40968411C" modified="2016-11-30" version="1">MSFDSERLDEVDEEDQSAEDQTMDDTSSLSSSPSIPDEDIDFDLVYALHTFAATVEGQASVMKGDALVLMEDTNIYWWLVEVIKSREIGYIPAENIETPYERLARLNKHRNIEITSPSANELNNTYYSTSSRQVTIVDESLYTVLYYEVESEIDPDELEQFIEEYEDTIEDGQVFEEEEEEEEEEENEEEEWCETPISEKAMIDEEGQITVEAYSAQEEQQHQSMSLRVFAGNIGQGPLFHTVSIRPATTAEELLQSAINKFGLQSSQSINEATIEYYLAVQGTDGDDYILSVQDKPYSIFKTLTDSLTTPMPSLSHIHRLSQPAQRRPRSSSFSNYEQTSFDEDSVIRFYLHRRIKRADEREGLVYIKVSLYPDHQKKKTEIDRIDKIIPVRQDSRIGDVIHLALEKFHIPDARASGFTVDSKKNGKRQLIHYKMFVRGNHQEVELESNEFMSTVLFQQQQASSYVGPITSDLLFVLRKGRKSTEIKLDSYSTERRPSILDILMENTPFNERRPNAASPIIAESPTRLTEQDRRQLNSLNNTQQPSSFTSSSFSSNKQFSDQMETDLKQDSRKKESLRQQFKRFVGWGSSSSSVTKKQQQQQLHTLTQSIPAFTPAATPSPTITPASTPTSMSVMIPYNNPDVVLPPSVNSTSDLDSISAPSTPLPPTPSTLPKPHPTNHSNTYSQNALLSQSTDNITPTTLEEVEDDEEEAEVDVFQNDSQSSNRITRQGSIASFDTTTSSVSPEEIAAATSYAFQSTEDDSDAEEMYHPHHEEQQEEQHTEPSAPTTPSVSLQPSVSSHHLQTSNTNAQHFNNLSKPSDVLTDVDHQTKSLADQPLPSSHETSSLHPMPHTDLDDLFLLVAHGIDFLTSKENTQWEEEGGYEFHPWNRPESSFAKVRKQEKKQQESTQYETSSTVNHLSSSSPPPTPIAKQTAVKVEQEDSSATLITSSSSYSTSSSASSSNSSSSSASSSHTSSHTGAQTELRMVPSKQSIAANESLSKSAIKHGLSNKKQAVDDEELQRIVAAHIVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NAU2</accession>
    <name>A0A1C7NAU2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Transmembrane and coiled-coil domain-containing protein 4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">Tmco4</name>
        <name evidence="7" type="ORF">A0J61_05718</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TMCO4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000317">
        <property type="protein sequence ID" value="OBZ86232.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NAU2"/>
    <dbReference type="FunCoup" id="A0A1C7NAU2">
        <property type="interactions" value="12"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NAU2"/>
    <dbReference type="InParanoid" id="A0A1C7NAU2"/>
    <dbReference type="OrthoDB" id="277931at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007941">
        <property type="entry name" value="DUF726"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17920:SF23">
        <property type="entry name" value="DUF726-DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17920">
        <property type="entry name" value="TRANSMEMBRANE AND COILED-COIL DOMAIN-CONTAINING PROTEIN 4 TMCO4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05277">
        <property type="entry name" value="DUF726"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="188"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="216"/>
            <end position="245"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OBZ86232.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="523" mass="58042" checksum="0A836F8CB3BB8D97" modified="2016-11-30" version="1">MEEPIVKLSRPEWTHKQCISIARLAAQALTETESLLTQSWSEQWWHTLLEYLELSQPELESHAITCSDALEILSNEEHDIRIEVLSDLLALALHITPTAMKEDAKQSKAKHVMLYDAKSKRFLLQMEKCLKLTPGDLGSVEKNIAQQMYYSLLEQQEKSDDPNIKSTMDLSTRKALSDSNKKKQALRWLATGAGVIGGGAVIALTGGLAAPLLGSILAGAGMSFFATAGGVALVTSLFGLTGGGLTGWKMHKRVKGLDQFEFKQILNDPDLPPIPALHCTICVSGFLLESKDETKTPWELAFEKNRTHDEIFCLEYETDELLELGYSFKKFVRDSAIKYAGMEVAKQTVLKAFFAAVTLPATILKMADVIDNPWQVVVNRSRLAGNLLADVLQERVQGSRPCSLIAYSCGSLVIWHCLLELNRRGLHGLVDNVVLMGAPISLEDTQEWQDALNVVSGRFVNCYSESDWVLAYVYRLHSLTTNVAGLEPVKNVSNRIENIMVEIDGHTKYPAAVKEVLDLLRLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NAY5</accession>
    <name>A0A1C7NAY5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Solute carrier family 2, facilitated glucose transporter member 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">SLC2A3_3</name>
        <name evidence="10" type="ORF">A0J61_05674</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000313">
        <property type="protein sequence ID" value="OBZ86285.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NAY5"/>
    <dbReference type="STRING" id="101091.A0A1C7NAY5"/>
    <dbReference type="InParanoid" id="A0A1C7NAY5"/>
    <dbReference type="OrthoDB" id="6612291at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015149">
        <property type="term" value="F:hexose transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045263">
        <property type="entry name" value="GLUT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00879">
        <property type="entry name" value="SP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23503:SF8">
        <property type="entry name" value="FACILITATED GLUCOSE TRANSPORTER PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23503">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00217">
        <property type="entry name" value="SUGAR_TRANSPORT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0762">Sugar transport</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="76"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="109"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="135"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="164"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="191"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="344"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="378"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="408"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="440"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="9">
        <location>
            <begin position="19"/>
            <end position="467"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OBZ86285.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="505" mass="54992" checksum="89981212E52881ED" modified="2016-11-30" version="1">MSKEIKSQDLGFPVYMTACASIAAISGFNVGWHISVPNMPEKIMKGIIEQDGSYHCLPGTDQGPLVGCLPMDNYTWGYTIGAYAIGGFFGSIASKYLNVKFGRRDNIMLSCLWMIIGGILSACAVNVGMYSVGRALVGVASGMCGSSVAIYVSEISTNKSRGALGSLFELFLNAGILLTQIAGRYLHPWRYLWAIPTLLAALQLALLSFFTVECPRRLCANRQYDQARTALDRLRAGADTEDEFKALMLARQQEAASAQAEMSIWDIISCKDRQVTWNTVIVMVVQAYNQIGGIGPISVYSVGFFTALFKDATLATNITLADASVNIVATLVAVVWMRQVGRRGFMMISTGGTCLASVMMVLGATLRNSQGTQGIGGLAIAAAVLFTGSYSMGCGVIPWMLAPELLPMHALAAGSALGNSSNWLFNFIINTIWPQMDQHLGTYSFVVFAVINLVGFLFVLFFMPETTDRDLDDHQTRRIDDFESLGDLGDCLSDKEDRRRRHHPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NBK8</accession>
    <name>A0A1C7NBK8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_05928</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000336">
        <property type="protein sequence ID" value="OBZ86016.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NBK8"/>
    <dbReference type="STRING" id="101091.A0A1C7NBK8"/>
    <dbReference type="InParanoid" id="A0A1C7NBK8"/>
    <dbReference type="OrthoDB" id="61900at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ86016.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="214" mass="24628" checksum="FD2B1EF00D3209B5" modified="2016-11-30" version="1">MEVKQTFEYFMLLEQQFWRNLDQESIQNITMKGQLKPENMLLYGEFGFTLIGLKHALLVEFCDEKVNILYLKTVIEPVLFASKSKTLSCHLIQHIVTPESDLHGCILVYHHDNLLPDISMLISKSKQEENAELSEDTMAAILDYPGHLPKDEEEIPTFLSVIYFHDKGGGDKGLTAVTSFAIQQKEKPTMFAHFERYKTASKQWLGIDLKLFVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NC86</accession>
    <name>A0A1C7NC86_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Dihydrofolate synthetase</fullName>
            <ecNumber evidence="7">6.3.2.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">fol3</name>
        <name evidence="9" type="ORF">A0J61_05233</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>7,8-dihydropteroate + L-glutamate + ATP = 7,8-dihydrofolate + ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:23584"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17839"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57451"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.2.12"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="7">Cofactor biosynthesis; tetrahydrofolylpolyglutamate biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the folylpolyglutamate synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.2.12" evidence="7"/>
    <dbReference type="EMBL" id="LUGH01000277">
        <property type="protein sequence ID" value="OBZ86723.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NC86"/>
    <dbReference type="FunCoup" id="A0A1C7NC86">
        <property type="interactions" value="225"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NC86"/>
    <dbReference type="InParanoid" id="A0A1C7NC86"/>
    <dbReference type="OrthoDB" id="5212574at2759"/>
    <dbReference type="UniPathway" id="UPA00850"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008841">
        <property type="term" value="F:dihydrofolate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004326">
        <property type="term" value="F:tetrahydrofolylpolyglutamate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006730">
        <property type="term" value="P:one-carbon metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.190.20">
        <property type="entry name" value="Mur ligase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1190.10">
        <property type="entry name" value="Mur-like, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001645">
        <property type="entry name" value="Folylpolyglutamate_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018109">
        <property type="entry name" value="Folylpolyglutamate_synth_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036565">
        <property type="entry name" value="Mur-like_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036615">
        <property type="entry name" value="Mur_ligase_C_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013221">
        <property type="entry name" value="Mur_ligase_cen"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01499">
        <property type="entry name" value="folC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11136:SF0">
        <property type="entry name" value="DIHYDROFOLATE SYNTHETASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11136">
        <property type="entry name" value="FOLYLPOLYGLUTAMATE SYNTHASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08245">
        <property type="entry name" value="Mur_ligase_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001563">
        <property type="entry name" value="Folylpolyglu_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53623">
        <property type="entry name" value="MurD-like peptide ligases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53244">
        <property type="entry name" value="MurD-like peptide ligases, peptide-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01011">
        <property type="entry name" value="FOLYLPOLYGLU_SYNT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 7" id="KW-0436">Ligase</keyword>
    <keyword evidence="6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-0554">One-carbon metabolism</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Mur ligase central" evidence="8">
        <location>
            <begin position="27"/>
            <end position="237"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008276"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRNR" id="PIRNR001563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF08245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OBZ86723.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="419" mass="46175" checksum="8D53ED3F8760BE02" modified="2016-11-30" version="1">MNFGLERIHRLLDALDRPDEKVKIIHVAGTNGKGSVCAYLASVLSASGYRVGRFNSPHLIEPRDSVVIDQQPVSALDYQQAMDYVDQLNKDVGASSFECLVGASLYLFARHQLDFVVLEVGLGGLLDATNAIRHPVMTIITSIGLDHAAILGNTLEAIAIAKAGIMKTGSPVVIAPNLKDVQQTLIDYATERGIQYKLAASAKWIEPNQLAQLESHRYPIPLLGDYQLENSATAVTALDWMQKLGHIQFTELQLEQGMTKTRWPGRLDWIRSDKYPSLQHKYGLEYLLVDGAHNLPAATALRQFIDQHMKGKQILWIMGVTEGKDVTHMIDMLVQPHDRLVAVPFSQPEGMPWIQCMDPMEIVKTAAPTTAPSAVSSLQEGLQTINQWIQQGPSDDAYAVVLCGSLYLVADLYRLIGGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NCB3</accession>
    <name>A0A1C7NCB3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Nuclear fragile X mental retardation-interacting protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">Nufip1</name>
        <name evidence="7" type="ORF">A0J61_05209</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000275">
        <property type="protein sequence ID" value="OBZ86745.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NCB3"/>
    <dbReference type="STRING" id="101091.A0A1C7NCB3"/>
    <dbReference type="InParanoid" id="A0A1C7NCB3"/>
    <dbReference type="OrthoDB" id="273070at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000492">
        <property type="term" value="P:box C/D snoRNP assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.1000.10">
        <property type="entry name" value="Zinc finger, CCCH-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039136">
        <property type="entry name" value="NUFIP1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019496">
        <property type="entry name" value="NUFIP1_cons_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000571">
        <property type="entry name" value="Znf_CCCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036855">
        <property type="entry name" value="Znf_CCCH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13309:SF0">
        <property type="entry name" value="FMR1-INTERACTING PROTEIN NUFIP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13309">
        <property type="entry name" value="NUCLEAR FRAGILE X MENTAL RETARDATION PROTEIN INTERACTING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10453">
        <property type="entry name" value="NUFIP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18345">
        <property type="entry name" value="zf_CCCH_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00356">
        <property type="entry name" value="ZnF_C3H1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90229">
        <property type="entry name" value="CCCH zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50103">
        <property type="entry name" value="ZF_C3H1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C3H1-type" evidence="6">
        <location>
            <begin position="265"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="4">
        <location>
            <begin position="265"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="143"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="203"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="347"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="210"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="347"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="380"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="397"/>
            <end position="407"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OBZ86745.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="419" mass="47542" checksum="174D90FC2D8E0308" modified="2016-11-30" version="1">MNNNNHHYGQYQPYYYPPYYPHNGNPVPQGDPSAALSSMMYYNTPAYYPYPPQDNQNYYYDQQRSMLTYDDLAHQTAPTPQPSRTPASLIHQQNTQPLEKPKFCCNRMLKTAMAIIQHEKLHVHCSDCDHKCLPSVMEEHEEIAHGKVSSKKKASRPDGIVPPNAPKINTPEELAAWIAARKKNWPSKANIERKEEEDKAKVARGELMSNKRKAATAEHHAKKTKIGDQLVQYSSDSESSDIDPEKDGVTSKDPSAMGKILLPEDRPKRRCKYFISGRCKRGDECTFLHEKPEPKPKQPRPTPAINRRPNLLFKLLEKEIQQEKNVILQCLRHLVDHDFLGLQKETAVQSKETSHPNNSIDNPNNPMDSISQPEEAVTNPVGSTTQPEESTSNLDEASVDEEGSEELAGEKWLCPNNLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NCR1</accession>
    <name>A0A1C7NCR1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Helitron helicase-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_05048</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000262">
        <property type="protein sequence ID" value="OBZ86903.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NCR1"/>
    <dbReference type="InParanoid" id="A0A1C7NCR1"/>
    <dbReference type="OrthoDB" id="2447509at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ86903.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="143" mass="16342" checksum="EE0B8AAD238B265B" modified="2016-11-30" version="1">MSNVCCTACNEPGYLRCTFRVHAIAGIHIATLQQLQQLMHRLNPFVSIFKNMMHIANGQPNEIESLENIKLVFRAEGVPNRRRYHRPAHGFEVAAIIVGGENDNDILNSRDIVVRYQDDSLIRVKELNQCHYTMSFCFPLGQT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NCV7</accession>
    <name>A0A1C7NCV7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">INO80 complex subunit B</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">Ino80b_1</name>
        <name evidence="4" type="synonym">Ino80b_0</name>
        <name evidence="4" type="ORF">A0J61_03770</name>
        <name evidence="3" type="ORF">A0J61_05366</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000287">
        <property type="protein sequence ID" value="OBZ86589.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="LUGH01000169">
        <property type="protein sequence ID" value="OBZ88191.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NCV7"/>
    <dbReference type="STRING" id="101091.A0A1C7NCV7"/>
    <dbReference type="InParanoid" id="A0A1C7NCV7"/>
    <dbReference type="OrthoDB" id="2021186at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031011">
        <property type="term" value="C:Ino80 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006338">
        <property type="term" value="P:chromatin remodeling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd23021">
        <property type="entry name" value="zf-HIT_IN80B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029523">
        <property type="entry name" value="INO80B/Ies2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006880">
        <property type="entry name" value="INO80B_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21561">
        <property type="entry name" value="INO80 COMPLEX SUBUNIT B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21561:SF12">
        <property type="entry name" value="INO80 COMPLEX SUBUNIT B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04795">
        <property type="entry name" value="PAPA-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01406">
        <property type="entry name" value="PAPA-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="INO80 complex subunit B-like conserved region" evidence="2">
        <location>
            <begin position="151"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="20"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="97"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="141"/>
            <end position="160"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM01406"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ86589.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OBZ88191.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="290" mass="33714" checksum="0355D17978BDD68D" modified="2016-11-30" version="1">MRPARRKAAPRHISPSPMSSEEEQSSSELEEFTANENEVFSEEEDLDQLDDNNDELESLSEEQLDEDDEMEEDEEEPPLPPKATLARTNKRKKQIIEESDEERFSEEDDDEILRNKPMTKRQRAKAYQEIPEEYLELPMDTGKKKQLTEEEEQLKKSEVARRRKNQSIQRAEKDKADTINRLLKKQASKSKRVIEDNAEDKETAHEKLKRLEDPNRLRYINTAQGSQLNIPTVFTLDKVFGTPIPQTQQPTLSSVKQCQVEGCLKARKYTAKKSGKFVCSLEHYKMVEVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-06-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7ND74</accession>
    <name>A0A1C7ND74_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_05243</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000278">
        <property type="protein sequence ID" value="OBZ86709.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7ND74"/>
    <dbReference type="InParanoid" id="A0A1C7ND74"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ86709.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="274" mass="31061" checksum="51E65ADCDD9BA0B2" modified="2016-11-30" version="1">MAEPIPGSQSNSEKTEDLSIDFEALFNFPRCPTTIPQINKNTFPKGYSIKSNNRPDCRSILKSKTKTKYDFEAKEIPRNHLKFNEQTKIFSSSHTVLNSSRLMNQSTEYTESKLKAATRLRCEKRSMPIITNKERNGTLLASDFIVENELRAARIRGGVHVKELPLVKQSFLGIDLEELLLMQPQPSIPLRTSKSSPSSLLRNKLHKAISRMKKSHSLGDIRKTNMSSDTLINCTTLPLHRKWSPFVTSSESLQIVDCSTLLPKPYTSGRRIVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NDK1</accession>
    <name>A0A1C7NDK1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Putative magnesium transporter NIPA8</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">A0J61_06493</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000394">
        <property type="protein sequence ID" value="OBZ85454.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NDK1"/>
    <dbReference type="InParanoid" id="A0A1C7NDK1"/>
    <dbReference type="OrthoDB" id="2504919at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015095">
        <property type="term" value="F:magnesium ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3730.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037185">
        <property type="entry name" value="EmrE-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008521">
        <property type="entry name" value="Mg_trans_NIPA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12570">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12570:SF86">
        <property type="entry name" value="ADR321CP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05653">
        <property type="entry name" value="Mg_trans_NIPA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103481">
        <property type="entry name" value="Multidrug resistance efflux transporter EmrE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="20"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="61"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="85"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="120"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="160"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="253"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="285"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="312"/>
            <end position="334"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OBZ85454.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="365" mass="41030" checksum="14A1CD700DB71EB8" modified="2016-11-30" version="1">MIDRITQLDNDNPEIAYTKQFWIGIGVSILTNLIQSFAMAFQRKSHLQNEKYPLEERKHSFQRPLWVISFATFLTANTIGSVFSIGYLPIVILAPISAMGLVFNAIAAKLVLGDPFKQRTVFGTLLIVLGALLVGLFGIIPEPDHDIDDLLRLYRKPSFIAYFSVLEFIIITGLIVTHYFERYYYLMESAAIPPTSLGKMMGQHLSMGELRKYVGISFGILSGNISSQSILFAKSGLELVLLSVLSDKNQLQYALTYVLLGMMLLTAILQLYYLNKGLQLCDTVIMIPLSSCTFNVSCLFNGLVYYDQWNRIAWWHLLLVMVGVAITISGVLLISWKPSAELLEEPIEILVEDDHERTGLLSKTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NE41</accession>
    <name>A0A1C7NE41_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Cofilin</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Actin-depolymerizing factor 1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">COF1</name>
        <name evidence="7" type="ORF">A0J61_04585</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus matrix</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the actin-binding proteins ADF family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000227">
        <property type="protein sequence ID" value="OBZ87365.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NE41"/>
    <dbReference type="FunCoup" id="A0A1C7NE41">
        <property type="interactions" value="171"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NE41"/>
    <dbReference type="InParanoid" id="A0A1C7NE41"/>
    <dbReference type="OrthoDB" id="10249245at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015629">
        <property type="term" value="C:actin cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016363">
        <property type="term" value="C:nuclear matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003779">
        <property type="term" value="F:actin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030042">
        <property type="term" value="P:actin filament depolymerization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11286">
        <property type="entry name" value="ADF_cofilin_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.20.10">
        <property type="entry name" value="Severin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002108">
        <property type="entry name" value="ADF-H"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029006">
        <property type="entry name" value="ADF-H/Gelsolin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017904">
        <property type="entry name" value="ADF/Cofilin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11913">
        <property type="entry name" value="COFILIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00241">
        <property type="entry name" value="Cofilin_ADF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00102">
        <property type="entry name" value="ADF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55753">
        <property type="entry name" value="Actin depolymerizing proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51263">
        <property type="entry name" value="ADF_H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0009">Actin-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ADF-H" evidence="6">
        <location>
            <begin position="2"/>
            <end position="135"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006844"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00015630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00032427"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51263"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OBZ87365.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="138" mass="15753" checksum="DE26DADDF1AEDE37" modified="2016-11-30" version="1">MSSGVAVNDECIQLYEELKIRKKYKYIIFKLNDTNSEIIVEKSAETADYDDFLAQLPADEPRYAVYDFDYEKGGEGKRSKITFYAWVPDTSKVRHKMVYASSKDALRRNLVGIAIEVQGTDSSEVDYETVLDKANRSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NE52</accession>
    <name>A0A1C7NE52_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_04563</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000226">
        <property type="protein sequence ID" value="OBZ87385.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NE52"/>
    <dbReference type="InParanoid" id="A0A1C7NE52"/>
    <dbReference type="OrthoDB" id="529205at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="39"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="50"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="97"/>
            <end position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ87385.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="107" mass="12060" checksum="AD9EDC1CA1EE3967" modified="2016-11-30" version="1">MYAATRTTAIAEVTKAYRSTIATSLASSTIKTTTRSMSAFSHMSDNDPEVLEKEKQKNLSKKDKEWNEKLASHSEASVKADKEHEKPIKNLQSETVEQLKKKESEDQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NE57</accession>
    <name>A0A1C7NE57_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Putative mannitol dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">ELI3</name>
        <name evidence="7" type="ORF">A0J61_04565</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 5">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the zinc-containing alcohol dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000226">
        <property type="protein sequence ID" value="OBZ87392.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NE57"/>
    <dbReference type="FunCoup" id="A0A1C7NE57">
        <property type="interactions" value="328"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NE57"/>
    <dbReference type="InParanoid" id="A0A1C7NE57"/>
    <dbReference type="OrthoDB" id="1879366at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016616">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05283">
        <property type="entry name" value="CAD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000022">
        <property type="entry name" value="Cinnamyl alcohol dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002328">
        <property type="entry name" value="ADH_Zn_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047109">
        <property type="entry name" value="CAD-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="ER"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42683">
        <property type="entry name" value="ALDEHYDE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00059">
        <property type="entry name" value="ADH_ZINC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Enoyl reductase (ER)" evidence="6">
        <location>
            <begin position="22"/>
            <end position="353"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU361277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OBZ87392.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="358" mass="39147" checksum="978F68A596E7EFC4" modified="2016-11-30" version="1">MVAQDKFTGYAGLQPFVLEDESTHLQVLQFEPRPLDEDEVEIKVAACGICGSDVHQLTNGWKRATYPIITGHEFIGQITAVGDKVQSLHVGQRVGVSPVCRSCGNCVQCQTEHAQLCPSKVTTYNGKYKGHTTYGGYADRVRVQARWAIPIPDNIDSEEGAPLLCAGITTYLPFKYYEIDDTKSVGVIGIGGLGHLALQWARAKKCPNIFAISTSSKKSDDAYKLGATDFVLIDKEGQFDDKYAQCVDVLLVCGSGKSTNWGKLTELVKTRGKIVLIDLPDEPVSLPLAALIYRHVSLVGTFVGSHEDLKEMLAFASETGVRPWIQTVENTLEGVNDGLKNLMQGKAHYRLVIKGEGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NEN2</accession>
    <name>A0A1C7NEN2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">CTLH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_04938</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000253">
        <property type="protein sequence ID" value="OBZ87016.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NEN2"/>
    <dbReference type="STRING" id="101091.A0A1C7NEN2"/>
    <dbReference type="InParanoid" id="A0A1C7NEN2"/>
    <dbReference type="OrthoDB" id="2415936at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013144">
        <property type="entry name" value="CRA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024964">
        <property type="entry name" value="CTLH/CRA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006595">
        <property type="entry name" value="CTLH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006594">
        <property type="entry name" value="LisH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050618">
        <property type="entry name" value="Ubq-SigPath_Reg"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12864">
        <property type="entry name" value="RAN BINDING PROTEIN 9-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10607">
        <property type="entry name" value="CTLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00757">
        <property type="entry name" value="CRA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50897">
        <property type="entry name" value="CTLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50896">
        <property type="entry name" value="LISH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CTLH" evidence="1">
        <location>
            <begin position="82"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="253"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50897"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ87016.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="253" mass="29736" checksum="5FFE4C3DE12FD588" modified="2016-11-30" version="1" fragment="single">MVLEEDCQAIVIEYLLHNCYQQSAKAFLKDIQCLNDCRHNNSPKDKRRDYLSEKNIEWNEIEIRKGSFFFFKKKASRELNISLLAIIHAIQQGDIAKAFSFMETHFPDLITAYNNYTPNDAQAHLLHSTLYKLRCQQFIETLRTSGDIKAVQFAQKYIRPWRKMYPDITNNVLILIAYHDLENENTRELLSQERRDKMAEQVNKIILASRQFSSSTSLEKIWRQKGLVEEQLTAEKAKESQKKFHEGNTKTLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NEY6</accession>
    <name>A0A1C7NEY6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">DASH complex subunit DAD4</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="16">Outer kinetochore protein DAD4</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="18" type="primary">DAD4</name>
        <name evidence="18" type="ORF">A0J61_04258</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18 19">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Chromosome</location>
            <location evidence="3">Centromere</location>
            <location evidence="3">Kinetochore</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
            <location evidence="2">Cytoskeleton</location>
            <location evidence="2">Spindle</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the DASH complex DAD4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000204">
        <property type="protein sequence ID" value="OBZ87693.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NEY6"/>
    <dbReference type="FunCoup" id="A0A1C7NEY6">
        <property type="interactions" value="2"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NEY6"/>
    <dbReference type="InParanoid" id="A0A1C7NEY6"/>
    <dbReference type="OrthoDB" id="5516652at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042729">
        <property type="term" value="C:DASH complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072686">
        <property type="term" value="C:mitotic spindle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008608">
        <property type="term" value="P:attachment of spindle microtubules to kinetochore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000278">
        <property type="term" value="P:mitotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013959">
        <property type="entry name" value="DASH_Dad4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28222">
        <property type="entry name" value="DASH COMPLEX SUBUNIT DAD4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28222:SF1">
        <property type="entry name" value="DASH COMPLEX SUBUNIT DAD4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08650">
        <property type="entry name" value="DASH_Dad4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="14" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="8" id="KW-0132">Cell division</keyword>
    <keyword evidence="15" id="KW-0137">Centromere</keyword>
    <keyword evidence="6" id="KW-0158">Chromosome</keyword>
    <keyword evidence="17" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="12" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="11" id="KW-0995">Kinetochore</keyword>
    <keyword evidence="9" id="KW-0493">Microtubule</keyword>
    <keyword evidence="10" id="KW-0498">Mitosis</keyword>
    <keyword evidence="13" id="KW-0539">Nucleus</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="17">
        <location>
            <begin position="13"/>
            <end position="40"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004629"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00009754"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00020259"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022838"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00030569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="OBZ87693.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="74" mass="8843" checksum="0C36E3F3188C5897" modified="2016-11-30" version="1">METPHEQQQAELLKRIITNISEFNHSLQKLNQKLESVRETDRNVDEIAQKWTHYHSASRLYIDNTKQDNHLNSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NFL8</accession>
    <name>A0A1C7NFL8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Basic leucine zipper and W2 domain-containing protein 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">BZW2</name>
        <name evidence="2" type="ORF">A0J61_04037</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000189">
        <property type="protein sequence ID" value="OBZ87911.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NFL8"/>
    <dbReference type="STRING" id="101091.A0A1C7NFL8"/>
    <dbReference type="InParanoid" id="A0A1C7NFL8"/>
    <dbReference type="OrthoDB" id="1727522at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051245">
        <property type="entry name" value="eIF5-mimic_regulator"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057397">
        <property type="entry name" value="HEAT_5MP1_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003307">
        <property type="entry name" value="W2_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14208">
        <property type="entry name" value="BASIC LEUCINE ZIPPER AND W2 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14208:SF2">
        <property type="entry name" value="PROTEIN KRASAVIETZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25504">
        <property type="entry name" value="HEAT_5MP1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02020">
        <property type="entry name" value="W2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00515">
        <property type="entry name" value="eIF5C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51363">
        <property type="entry name" value="W2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="W2" evidence="1">
        <location>
            <begin position="253"/>
            <end position="422"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ87911.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="423" mass="48454" checksum="D13789C56D2D11D6" modified="2016-11-30" version="1">MNSTQPQANSKPTLHGVKIKQRKGVQKANAKHEPEIFRDQLLAQFKTIKEGDFDAFSVKLDNLGNTLDYRKYGDSLFEILITGGILEPGGIIDDDAERSPFCVFAAEDDAAVIKKYVDVFNKLIRRYKYLQRIFGETLQNLLQFINKWQVEENSKLAKATGFLISTQVCPASVLKVLLQDYLVKDGHALNFTTTVFRTVLDEQSIEQLGRVLAAEGLNSRLIEFFPPNKRDEDCLVRHFEAEDMKDLVDYYRRNKKNSIKGSLLNELSEKMQEEEANEAEVLSLIKSNVKDAGLTEGDIVAIIWQSMMSTVDLLNSRADQVESQVLRAINQWSKMIEEFCNSPKTEIVLLQKVQSTCYEDVKLTKSFRRVIQTLYKNDVLSDNAILYWNDKAHLAQGKTLFLKQIEPFITWLRENEDSSEEED</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-06-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NGW7</accession>
    <name>A0A1C7NGW7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_03958</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000183">
        <property type="protein sequence ID" value="OBZ87989.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NGW7"/>
    <dbReference type="InParanoid" id="A0A1C7NGW7"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ87989.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="76" mass="8632" checksum="3595FC95E5525ACC" modified="2016-11-30" version="1">MPTIDDFTKKKLPCSNSEVSNDDFCVFIGDYMKTEKDLMHDEVVNSTPLFYSVIDPEGKDMTLEVPKKTISDKHTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NHB9</accession>
    <name>A0A1C7NHB9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">W2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">A0J61_03524</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000153">
        <property type="protein sequence ID" value="OBZ88425.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NHB9"/>
    <dbReference type="STRING" id="101091.A0A1C7NHB9"/>
    <dbReference type="InParanoid" id="A0A1C7NHB9"/>
    <dbReference type="OrthoDB" id="2290605at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005851">
        <property type="term" value="C:eukaryotic translation initiation factor 2B complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005085">
        <property type="term" value="F:guanyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031369">
        <property type="term" value="F:translation initiation factor binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051956">
        <property type="entry name" value="eIF2B_epsilon"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003307">
        <property type="entry name" value="W2_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45887">
        <property type="entry name" value="TRANSLATION INITIATION FACTOR EIF-2B SUBUNIT EPSILON"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45887:SF1">
        <property type="entry name" value="TRANSLATION INITIATION FACTOR EIF-2B SUBUNIT EPSILON"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02020">
        <property type="entry name" value="W2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00515">
        <property type="entry name" value="eIF5C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51363">
        <property type="entry name" value="W2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="W2" evidence="3">
        <location>
            <begin position="218"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="72"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="456"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="140"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="456"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="476"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OBZ88425.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="485" mass="56308" checksum="E62286EE0867AE7D" modified="2016-11-30" version="1" fragment="single">TMNSLIHSHHLIDMEYCLNDRSPRKVPLCIAAAVYRISAGNCMPNTNQSFSLMQHSSPWDYCRRQKKAEESSLEDSTCSSRSDSPEPKSKKRSTHLLLREIHRLRGENATLRHSVSILKNDLRDIALSRQDTDASHKRVYEEYLDRNAQLENDVQDRDDEIARLRKEIEQLKSIQLTDPLEEQPSQSVEEQQAIDDYFHRRHMDCYGLNQHFLATEEEEEEEEEEMEAFEEIACSYLQQAMLSRLSSARVRLELDDLICKHEPSSATLIDALTDAFVRWIGSLIQKNERRSQPMSVPKLFTTEVQEGIAEFWESVFQHYLMDDHSQQQLLFQIETTLANLSFGVIVANHFDRLVLLLFKHLVIDDDALIGWWQHPLDDEVSRQIRKITTRFVEWVQDSEEEESEEEEEDVFSFVESPVPEDTVELDVSDNDDSIDDLLSHTRHYCVCLSDNDTSNNAPNQHECSCSTYTPSPVPEKKKKSVRIAM</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NHG4</accession>
    <name>A0A1C7NHG4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Tetratricopeptide repeat protein 36</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">TTC36</name>
        <name evidence="2" type="ORF">A0J61_05156</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the TTC36 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000271">
        <property type="protein sequence ID" value="OBZ86794.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NHG4"/>
    <dbReference type="STRING" id="101091.A0A1C7NHG4"/>
    <dbReference type="InParanoid" id="A0A1C7NHG4"/>
    <dbReference type="OrthoDB" id="539634at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006570">
        <property type="term" value="P:tyrosine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038906">
        <property type="entry name" value="TTC36"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21405">
        <property type="entry name" value="CDNA SEQUENCE BC021608"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21405:SF0">
        <property type="entry name" value="TETRATRICOPEPTIDE REPEAT PROTEIN 36"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13431">
        <property type="entry name" value="TPR_17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ86794.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="183" mass="20755" checksum="E762CAD9A9D3236D" modified="2016-11-30" version="1">MSISDDAVLEFMFNPENQGLPLDAISCTVDSNPKYTFSDETLAKLESMEKEAVVLVEKDQDTEKALSILNQCIDMEKNYASAYNNRAQIYRMKNKLDEALQDLNFVIEDAGEGQPKILRQAYTQRAVIKRQQGDVVGSRKDFEIGAKLGNPLARQIAVNENPYAKMCNQVMMEVMNRERMMGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NHW6</accession>
    <name>A0A1C7NHW6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Large ribosomal subunit protein bL17c</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">50S ribosomal protein L17, chloroplastic</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">CL17</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">rplQ</name>
        <name evidence="8" type="ORF">A0J61_03243</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the bacterial ribosomal protein bL17 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000136">
        <property type="protein sequence ID" value="OBZ88701.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NHW6"/>
    <dbReference type="FunCoup" id="A0A1C7NHW6">
        <property type="interactions" value="308"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NHW6"/>
    <dbReference type="InParanoid" id="A0A1C7NHW6"/>
    <dbReference type="OrthoDB" id="275000at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005762">
        <property type="term" value="C:mitochondrial large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.1030.10:FF:000001">
        <property type="entry name" value="50S ribosomal protein L17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1030.10">
        <property type="entry name" value="Ribosomal protein L17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01368">
        <property type="entry name" value="Ribosomal_bL17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000456">
        <property type="entry name" value="Ribosomal_bL17"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047859">
        <property type="entry name" value="Ribosomal_bL17_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036373">
        <property type="entry name" value="Ribosomal_bL17_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00059">
        <property type="entry name" value="L17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14413:SF16">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN BL17M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14413">
        <property type="entry name" value="RIBOSOMAL PROTEIN L17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01196">
        <property type="entry name" value="Ribosomal_L17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64263">
        <property type="entry name" value="Prokaryotic ribosomal protein L17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01167">
        <property type="entry name" value="RIBOSOMAL_L17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 7 8" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00072708"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00077677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00082728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000660"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OBZ88701.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="190" mass="21431" checksum="39E099CA52947551" modified="2016-11-30" version="1">MHHGKHLRRLNRDSAHRNSLLRNLVSSLIEHGRIETTVAKAKTIQPLADAMITLGKRGDVEAKKQALAFLNSRDTTVPKLFDELASRFKERQGGYTRIQRIGKRYGDNAPMAIIEYIDGPTDTKREMVTSTLARKFSNTQPLSVKELLDNTEKAESLGLSKTLIRNLKKVQFSNSIETIDQAIEKKMSSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NHX8</accession>
    <name>A0A1C7NHX8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_04995</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000258">
        <property type="protein sequence ID" value="OBZ86944.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NHX8"/>
    <dbReference type="InParanoid" id="A0A1C7NHX8"/>
    <dbReference type="OrthoDB" id="2441332at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ86944.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="379" mass="42175" checksum="52A79028E402EAD8" modified="2016-11-30" version="1" fragment="single">LTLGVEDLSDKLMSYRRSAVSEAANGSKLSDTHLLALNYIYCFDLKMNFLEEIGAMHHLKELRNILLVSYGYKPCQDSLQLLCNKVLQLMVVGEKKKANETILLELLDANNNDDEQKTLMLNVLAAFAKKVETYSAATEQSYVESTLVPWLENYFNSISNTKWASCHGLLEPLAKQPALLEAFDSSAITTSSSTATATKRSRACGVSSWLSLSPDYLLKVSVGCQDFDVFLCEFKKPGATPSQLVPDKAKLANMMKIMLDRLVLLGVSAPVVCGLIDDGQYTATYKMVIQDDGCYAFVQLASFRGIRCMSDLVMIPTIMSFYDQLKAIILDTKSKIEIAMLKEVLPGPLVLPVVPCSWLRPSFEYPRVVDTEKRQKTPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NI41</accession>
    <name>A0A1C7NI41_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">12-oxophytodienoate reductase 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">OPR1_7</name>
        <name evidence="5" type="ORF">A0J61_03531</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the NADH:flavin oxidoreductase/NADH oxidase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000153">
        <property type="protein sequence ID" value="OBZ88429.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NI41"/>
    <dbReference type="FunCoup" id="A0A1C7NI41">
        <property type="interactions" value="288"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NI41"/>
    <dbReference type="InParanoid" id="A0A1C7NI41"/>
    <dbReference type="OrthoDB" id="276546at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016628">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd02933">
        <property type="entry name" value="OYE_like_FMN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.70:FF:000059">
        <property type="entry name" value="N-ethylmaleimide reductase, FMN-linked"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001155">
        <property type="entry name" value="OxRdtase_FMN_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045247">
        <property type="entry name" value="Oye-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22893">
        <property type="entry name" value="NADH OXIDOREDUCTASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22893:SF91">
        <property type="entry name" value="NADPH DEHYDROGENASE 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00724">
        <property type="entry name" value="Oxidored_FMN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51395">
        <property type="entry name" value="FMN-linked oxidoreductases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NADH:flavin oxidoreductase/NADH oxidase N-terminal" evidence="4">
        <location>
            <begin position="8"/>
            <end position="325"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00724"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OBZ88429.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="350" mass="38735" checksum="B7730730A804E38F" modified="2016-11-30" version="1">MSAANSALLAPVKVGRYQLNHRVVLAPLTRFRATTEAGLLITEATFINRLAGGFPQAPGIYNQEQIDGWKKVTEAVHKKGGVIFLQLWHVGRTGSKYLNPNLEQVVSASEIAVRGKHYDGRDTEVPRALTVEEIGLLVQDYRQAALNAIEAGFDGVEVHSANGHLVDQFINSSSNKRTDQYGGSIENRTRFALEIVDAIAGAIGADRTAIRFSPGSEIQDVHDDTPVETWGYLISQIQQNHPDFAYLHLVEPRGDAFGNTTNSDDSLEPYRKIWKGPLVVASGFSTNIPHAIDLAEKTGNLVAFGRAFIANPDLPERIRNGWELNEYDRSTFYTNEAKGYTDYPFYKSKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NI46</accession>
    <name>A0A1C7NI46_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Microphthalmia-associated transcription factor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">Mitf_0</name>
        <name evidence="9" type="ORF">A0J61_03136</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000130">
        <property type="protein sequence ID" value="OBZ88813.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NI46"/>
    <dbReference type="STRING" id="101091.A0A1C7NI46"/>
    <dbReference type="InParanoid" id="A0A1C7NI46"/>
    <dbReference type="OrthoDB" id="690068at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.280.10">
        <property type="entry name" value="Helix-loop-helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011598">
        <property type="entry name" value="bHLH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036638">
        <property type="entry name" value="HLH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45776">
        <property type="entry name" value="MIP04163P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45776:SF2">
        <property type="entry name" value="MIP04163P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00010">
        <property type="entry name" value="HLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00353">
        <property type="entry name" value="HLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47459">
        <property type="entry name" value="HLH, helix-loop-helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50888">
        <property type="entry name" value="BHLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="BHLH" evidence="8">
        <location>
            <begin position="251"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="52"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="295"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="70"/>
            <end position="91"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50888"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OBZ88813.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="343" mass="38323" checksum="CE3A83661E8ABE2B" modified="2016-11-30" version="1">MNTNEFQFNNRSTLGTRLLNPTSYHMQHMKSNEDTSSGQINPSQMLESTQLYLSHHQQDSPALSDLDYSELTNSPVTGSATVTNESNSSNGAGEYQHHSRQSSSISYQHNANSGDNYVFDNADMKPFGYGGFGVQMKRSSTETKTAAIGGMTSAGYGQVHHPFFSMSTFDHHHSPEERYMKQMAGSAPSNMGFHGYSSFAGSDDMNSIANSQPCNTITNLSHNGDLLDDSYNGDDFSTQANMQAIMEKRRRRRESHNAVERRRRDNINERIQELGTLLPESVDDGVNRMNKGTILRKSVEQIRKLQNDVVQHRQRIRDLEVILQQVGQQNLGRGGMPASNNMS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NIT7</accession>
    <name>A0A1C7NIT7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Velvet domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">A0J61_02897</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000116">
        <property type="protein sequence ID" value="OBZ89057.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NIT7"/>
    <dbReference type="STRING" id="101091.A0A1C7NIT7"/>
    <dbReference type="InParanoid" id="A0A1C7NIT7"/>
    <dbReference type="OrthoDB" id="5599552at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.3960">
        <property type="entry name" value="Velvet domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021740">
        <property type="entry name" value="Velvet"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037525">
        <property type="entry name" value="Velvet_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038491">
        <property type="entry name" value="Velvet_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33572">
        <property type="entry name" value="SPORE DEVELOPMENT REGULATOR VOSA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33572:SF18">
        <property type="entry name" value="SPORE DEVELOPMENT REGULATOR VOSA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11754">
        <property type="entry name" value="Velvet"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51821">
        <property type="entry name" value="VELVET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Velvet" evidence="6">
        <location>
            <begin position="18"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="188"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="227"/>
            <end position="248"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51821"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OBZ89057.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="337" mass="37687" checksum="0487EE682B3F48FC" modified="2016-11-30" version="1">MSKAHHYNYISACPTTASSSSLYSLISRQQPIHARISTNNERDRRPIDPPPIIQIKLTNATPQETDTFHQSSYFFMCANLAHVSDDNEIYTPTHNALSGQTVSSMYKLKDIDNDNGAFFVFGDLSVKVEGQFRLKLSLFEITCTGAVCLQSIFTSPFIVYPSKKFPGALDSTFLSRNFSDQGARIRIKKENRSQLSTSNTPCKRKLEIQTEPTSPTGQHPYLEKRGSITNSDTTESNSSQGSPVTSHLASPCAVSLPPLSPPTQSYDKQWLPSDYSQGYCLHPEPTIRLPPISSFLPLEQIKRQKTEDDSLAAAAMIQLHHQPYYTAPRKHHLIHLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NJ02</accession>
    <name>A0A1C7NJ02_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Myb-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_02879</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000115">
        <property type="protein sequence ID" value="OBZ89071.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NJ02"/>
    <dbReference type="InParanoid" id="A0A1C7NJ02"/>
    <dbReference type="OrthoDB" id="2143914at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001005">
        <property type="entry name" value="SANT/Myb"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50090">
        <property type="entry name" value="MYB_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Myb-like" evidence="2">
        <location>
            <begin position="135"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="72"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="120"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="128"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ89071.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="213" mass="24885" checksum="4222384277B7E0F2" modified="2016-11-30" version="1">MDLKYLLCEPISRLSVQANPIELARKQPIDLEWPTKPIYHTNQQEWYQDQPTMIISSPRSVCSSISACSSTSSTSSQDDLNHVTSPHNHLDPSRLYPYQSRRRTASDVSLTRHHMFIYSHPNRRPRSKSTGNNDQPIQTRTPWTPFEDHLLRQGYDQGLSWAMISSTYLPHRSRGCCWGRFKTLQNKNMVDPAHSQMRHFRRPWKAIDFHPSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NJ58</accession>
    <name>A0A1C7NJ58_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Phospholipid:diacylglycerol acyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">plh1_1</name>
        <name evidence="1" type="ORF">A0J61_02816</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000111">
        <property type="protein sequence ID" value="OBZ89143.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NJ58"/>
    <dbReference type="FunCoup" id="A0A1C7NJ58">
        <property type="interactions" value="207"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NJ58"/>
    <dbReference type="InParanoid" id="A0A1C7NJ58"/>
    <dbReference type="OrthoDB" id="190846at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008374">
        <property type="term" value="F:O-acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003386">
        <property type="entry name" value="LACT/PDAT_acylTrfase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11440">
        <property type="entry name" value="LECITHIN-CHOLESTEROL ACYLTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02450">
        <property type="entry name" value="LCAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ89143.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="719" mass="81064" checksum="165D53AEAC3C2BE0" modified="2016-11-30" version="1">MLRKRIGFLFNTGEDDKPRPIIKKTISLKSVGEQPEDILADCTIFEQENPVLWKRKRFHFIVGLSVGLLAAYAASKTPAAQTHFNDIQSYLNLHLSDMDLPKMLAMTDMVDELFGNFTSFFSYAPSTEQAFMPALAFKDEMDLKPHFPVVMIPGIISSGLESWGSAEKSRKFFRKRMWGTTTMFRSVLLEKDLWIEHLKLDPVTGLDPPGIKIRAAQGFDAADYFESMGELTCEDSYWIWAKIIENLAFIGYDNNNMFLASYDWRLSFTNLEVRDHYFTKLQTVIETSRKTNQKPAVMITHSMGASMFPYFLRWVQSPEGGNGGEKWTEEHIASFVNIAGPMTGVPKALTALLSGETRDTMSLGSFSAYLLEKFFSRRERASLVRSWSGGSSMLPKGGHLIWGTHDSAPDDDSNAMYHSYGNIISFTKTNEEEATVEEKDKNKTTEKMVNKDVDQNYDVNSSIDLLHQSASPEFSAMLQSNYSFGITTSKKQLKKNNLDHRKWSNPLESQLPIAPNMKIYCMYGVGLPTERSYYYTRAKDDLKASQEDMDYDVLKLLNGTSIREEEFIDAVVKESIGKTETSNSTDDVPHPPSIYIDRAMHEPSKGVETGVRFSDGDGTVPLLSLGYMCAPSGGWTKYADLYNPGHSPVVLREYPNELSDSKLEVRGGSKAGDHVDILGNWEMTLDILQIVSNKGENVTQRIVSQIEQYAKKIQLEPLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NJH5</accession>
    <name>A0A1C7NJH5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 14">Dolichyl-phosphate-mannose--protein mannosyltransferase</fullName>
            <ecNumber evidence="4 14">2.4.1.109</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="primary">PMT4_0</name>
        <name evidence="17" type="ORF">A0J61_02641</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="14">Transfers mannose from Dol-P-mannose to Ser or Thr residues on proteins.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13 14">
            <text>a di-trans,poly-cis-dolichyl beta-D-mannosyl phosphate + L-seryl-[protein] = 3-O-(alpha-D-mannosyl)-L-seryl-[protein] + a di-trans,poly-cis-dolichyl phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17377"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:13546"/>
            <dbReference type="Rhea" id="RHEA-COMP:19498"/>
            <dbReference type="Rhea" id="RHEA-COMP:19501"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:57683"/>
            <dbReference type="ChEBI" id="CHEBI:58211"/>
            <dbReference type="ChEBI" id="CHEBI:137321"/>
            <dbReference type="EC" id="2.4.1.109"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12 14">
            <text>a di-trans,poly-cis-dolichyl beta-D-mannosyl phosphate + L-threonyl-[protein] = 3-O-(alpha-D-mannosyl)-L-threonyl-[protein] + a di-trans,poly-cis-dolichyl phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:53396"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:13547"/>
            <dbReference type="Rhea" id="RHEA-COMP:19498"/>
            <dbReference type="Rhea" id="RHEA-COMP:19501"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:57683"/>
            <dbReference type="ChEBI" id="CHEBI:58211"/>
            <dbReference type="ChEBI" id="CHEBI:137323"/>
            <dbReference type="EC" id="2.4.1.109"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 14">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 14">Endoplasmic reticulum membrane</location>
            <topology evidence="1 14">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 14">Belongs to the glycosyltransferase 39 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.109" evidence="4 14"/>
    <dbReference type="EMBL" id="LUGH01000102">
        <property type="protein sequence ID" value="OBZ89302.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NJH5"/>
    <dbReference type="FunCoup" id="A0A1C7NJH5">
        <property type="interactions" value="241"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NJH5"/>
    <dbReference type="InParanoid" id="A0A1C7NJH5"/>
    <dbReference type="OrthoDB" id="292747at2759"/>
    <dbReference type="UniPathway" id="UPA00378"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004169">
        <property type="term" value="F:dolichyl-phosphate-mannose-protein mannosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.80.10.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003342">
        <property type="entry name" value="ArnT-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036300">
        <property type="entry name" value="MIR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016093">
        <property type="entry name" value="MIR_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027005">
        <property type="entry name" value="PMT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032421">
        <property type="entry name" value="PMT_4TMC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10050">
        <property type="entry name" value="DOLICHYL-PHOSPHATE-MANNOSE--PROTEIN MANNOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10050:SF51">
        <property type="entry name" value="PROTEIN O-MANNOSYL-TRANSFERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02815">
        <property type="entry name" value="MIR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02366">
        <property type="entry name" value="PMT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16192">
        <property type="entry name" value="PMT_4TMC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00472">
        <property type="entry name" value="MIR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82109">
        <property type="entry name" value="MIR domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50919">
        <property type="entry name" value="MIR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 14" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="5 14 17" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="11 14" id="KW-0472">Membrane</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0677">Repeat</keyword>
    <keyword evidence="6 14 17" id="KW-0808">Transferase</keyword>
    <keyword evidence="7 14" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10 14" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="58"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="111"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="143"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="169"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="194"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="224"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="256"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="576"/>
            <end position="594"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="615"/>
            <end position="633"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="645"/>
            <end position="669"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="690"/>
            <end position="710"/>
        </location>
    </feature>
    <feature type="domain" description="MIR" evidence="16">
        <location>
            <begin position="313"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="domain" description="MIR" evidence="16">
        <location>
            <begin position="382"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="domain" description="MIR" evidence="16">
        <location>
            <begin position="442"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="15">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="15">
        <location>
            <begin position="22"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00045085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00045102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU367007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="OBZ89302.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="740" mass="85090" checksum="2E035C8657505ECE" modified="2016-11-30" version="1">MGTLSTHLSSNELRHRTTKPIAAKETKDKTTPHFEEDIDTIKKNTHHNNHWHEHTHQLASTLVVIMSFFTTFYKIWYPAQVVFDEVHFGKFAGYYLQRTFFFDVHPPLAKLMYAAVGYLVGFDGVYQFTTIGESYADNQVPYIALRALPAALNVLSVALVYRILKSSGASILTCFLVSTLYCLDNAFIGQNRLILLDSMLIFFMLTTIYSYVEFRRHRHLVKMVGLFTVAAIGVAVVIDLWDLLDYKKHGLSNRQFIHHFFARFASLIVIPCVVYMFWFYVHFEILKFSGPGDVYMSAAFQETLHNNPLRLQSLEIMYNQVIRLQHRETSAFLHSHSLPYPGQYEDGRYSSQGIQVTGNPKPDANSYWRIKPTKELDPTSTTHYVRHNDIIQLEHVASQLNLMTHNVAAPLTPTHQEFTVVNHEKHYNDTLFRLELDDAVHSDIWSTMTKSVRLIHVNTGAALWCNSKHLPAWGASHFEVNGNRLASQPKNYWMATEIFGLNATEINLEKNKQVRSMSFLVKFIDLQMRMIVHNNRLVGSHPYQSTPISWPLMTRGISYWTDSATRGQIYLTGNIAGWWVGFTCLGLFALGYLGHQMIEKRRDCLVIHPTVKTRLTRTGGFFFLLWALHYLPFYLMGRSLFLHHYLPAMACNYLLLGSVFEYLFVNGVNSPASYQPNEKKLSVNQARLKIKSFLAASVLLGMQFMVYLFLSPLTYGDSGLPVEEIARRKVLEGWDIQFVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NJT3</accession>
    <name>A0A1C7NJT3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_02565</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000098">
        <property type="protein sequence ID" value="OBZ89391.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NJT3"/>
    <dbReference type="InParanoid" id="A0A1C7NJT3"/>
    <dbReference type="OrthoDB" id="2207883at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ89391.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="70" mass="8489" checksum="B529B675A5B3C872" modified="2016-11-30" version="1">MSDNKKATFWNPRPNSDIKKPSDRMTFCRPRTHDFSDAAWDRKYEIWYQQEPAIEFKYSKSQDKKKGDNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NJY4</accession>
    <name>A0A1C7NJY4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Cysteine synthase 1</fullName>
            <ecNumber evidence="4">2.5.1.47</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="14">O-acetylserine (thiol)-lyase 1</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="15">O-acetylserine sulfhydrylase 1</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="16">O-succinylserine sulfhydrylase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="18" type="primary">cysB_2</name>
        <name evidence="18" type="ORF">A0J61_02642</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18 19">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Catalyzes the conversion of O-succinyl-L-serine into cysteine, the last step in the cysteine biosynthesis pathway. Can also use O-acetyl-L-serine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>O-acetyl-L-serine + hydrogen sulfide = L-cysteine + acetate</text>
            <dbReference type="Rhea" id="RHEA:14829"/>
            <dbReference type="ChEBI" id="CHEBI:29919"/>
            <dbReference type="ChEBI" id="CHEBI:30089"/>
            <dbReference type="ChEBI" id="CHEBI:35235"/>
            <dbReference type="ChEBI" id="CHEBI:58340"/>
            <dbReference type="EC" id="2.5.1.47"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>O-succinyl-L-serine + hydrogen sulfide = L-cysteine + succinate</text>
            <dbReference type="Rhea" id="RHEA:53816"/>
            <dbReference type="ChEBI" id="CHEBI:29919"/>
            <dbReference type="ChEBI" id="CHEBI:30031"/>
            <dbReference type="ChEBI" id="CHEBI:35235"/>
            <dbReference type="ChEBI" id="CHEBI:136856"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Amino-acid biosynthesis; L-cysteine biosynthesis; L-cysteine from L-serine: step 2/2.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.47" evidence="4"/>
    <dbReference type="EMBL" id="LUGH01000102">
        <property type="protein sequence ID" value="OBZ89300.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NJY4"/>
    <dbReference type="FunCoup" id="A0A1C7NJY4">
        <property type="interactions" value="464"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NJY4"/>
    <dbReference type="InParanoid" id="A0A1C7NJY4"/>
    <dbReference type="OrthoDB" id="10259545at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004124">
        <property type="term" value="F:cysteine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006535">
        <property type="term" value="P:cysteine biosynthetic process from serine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01561">
        <property type="entry name" value="CBS_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1100:FF:000011">
        <property type="entry name" value="Cysteine synthase (o-acetylserine)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1100">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050214">
        <property type="entry name" value="Cys_Synth/Cystath_Beta-Synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001216">
        <property type="entry name" value="P-phosphate_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001926">
        <property type="entry name" value="TrpB-like_PALP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036052">
        <property type="entry name" value="TrpB-like_PALP_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF007989">
        <property type="entry name" value="PRK10717.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10314">
        <property type="entry name" value="CYSTATHIONINE BETA-SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00291">
        <property type="entry name" value="PALP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53686">
        <property type="entry name" value="Tryptophan synthase beta subunit-like PLP-dependent enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00901">
        <property type="entry name" value="CYS_SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="9" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="7" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <keyword evidence="8" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="Tryptophan synthase beta chain-like PALP" evidence="17">
        <location>
            <begin position="30"/>
            <end position="326"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012681"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00047931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00050981"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00058228"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00072087"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00078262"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00079147"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00081847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF00291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="OBZ89300.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="361" mass="39077" checksum="B8F088415415C564" modified="2016-11-30" version="1">MNSLRLIARRAYSTVHPGSRPGITNGFIGAIGNTPLIRLNKLSEETGSEILAKAEFMNPGGSVKDRAALYVVKDAEEKGLIKPGGTVVEGTAGNTGIGLAHVCRAKGYKCVIYMPNTQSQEKIDLLRMLGAEVYPVPAVAFDNPQNYNHQAKRHAESLENAVWTNQFDNTANRRAHIETTGPEIFAQTNGEVDGFVCATGTGGSLAGTARYLKDQKGDQVKVFIADPPGSVLHSYFTSGRKLFERSGSSITEGIGQGRITDNLGPDVDLIDGALHIPDEETIKMVYRLLDEEGIYVGASSALNAVAAVEMAKQLGKGKKIVTLLCDGAYRYQSRLFSRQWLEAKKLSQAIPDHLQKYVVLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NKU1</accession>
    <name>A0A1C7NKU1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">catalase</fullName>
            <ecNumber evidence="3">1.11.1.6</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">A0J61_02198</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the catalase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.11.1.6" evidence="3"/>
    <dbReference type="EMBL" id="LUGH01000080">
        <property type="protein sequence ID" value="OBZ89741.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NKU1"/>
    <dbReference type="STRING" id="101091.A0A1C7NKU1"/>
    <dbReference type="InParanoid" id="A0A1C7NKU1"/>
    <dbReference type="OrthoDB" id="6880011at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004096">
        <property type="term" value="F:catalase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042744">
        <property type="term" value="P:hydrogen peroxide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006979">
        <property type="term" value="P:response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.91.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024712">
        <property type="entry name" value="Catalase_clade2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011614">
        <property type="entry name" value="Catalase_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020835">
        <property type="entry name" value="Catalase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42821">
        <property type="entry name" value="CATALASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42821:SF1">
        <property type="entry name" value="CATALASE-B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00199">
        <property type="entry name" value="Catalase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56634">
        <property type="entry name" value="Heme-dependent catalase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0349">Heme</keyword>
    <keyword evidence="9" id="KW-0376">Hydrogen peroxide</keyword>
    <keyword evidence="8" id="KW-0408">Iron</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="10">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008889771" description="catalase" evidence="10">
        <location>
            <begin position="25"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="domain" description="Catalase core" evidence="11">
        <location>
            <begin position="44"/>
            <end position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012314"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="OBZ89741.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="83" mass="9397" checksum="CE68B13547EEE129" modified="2016-11-30" version="1">MRYRSGLSLTGLLAFFIAIVPTYQDTRPLPVQEAVRVDAGTTVTTMFGQKVNDTDSLIIGERGPTLLEDFILREKVMHFDHER</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NLH5</accession>
    <name>A0A1C7NLH5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative choline kinase 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_02640</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the choline/ethanolamine kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000102">
        <property type="protein sequence ID" value="OBZ89316.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NLH5"/>
    <dbReference type="FunCoup" id="A0A1C7NLH5">
        <property type="interactions" value="409"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NLH5"/>
    <dbReference type="InParanoid" id="A0A1C7NLH5"/>
    <dbReference type="OrthoDB" id="10267235at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004103">
        <property type="term" value="F:choline kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004305">
        <property type="term" value="F:ethanolamine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006646">
        <property type="term" value="P:phosphatidylethanolamine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05157">
        <property type="entry name" value="ETNK_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1200.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22603">
        <property type="entry name" value="CHOLINE/ETHANOALAMINE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22603:SF93">
        <property type="entry name" value="RE24176P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01633">
        <property type="entry name" value="Choline_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00038211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ89316.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="378" mass="43252" checksum="5874FE412B3E91A6" modified="2016-11-30" version="1">MSTTTETRPGLSTLLKSKIGKLHHAPKRIASSSRSKSSPALLVAAHELRAKPIPSCQTMLDLSILNEEELIQTVSHLIHQLFSISDSNLKLQRVSGALTNAVFFVTLSNKKRMLLRVYGVGCDQILDRNKELDWLSRLSALHIGPRLLGIFGNGRFEEYLPSTTLTPNEIRTPTISQQIASRLKQLHSIVDTYPRTSEPLEVWANIDKWRAEQIESELNLIQLRQEIESCKAVLNQSNSPTVFAHNDTQYGNILKINGTGELVVIDFEYAGYNPRAMDIVNHFCEWMYDYHSQSPSTMHLDQYPSREEQARFLASYLDTEDQDQIEALMSEVAAWKMACHLFWALWGFVQASQSEIDFDYFHYSIQRLQAFRSELKRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NLS1</accession>
    <name>A0A1C7NLS1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Actin-binding protein F</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">abpF</name>
        <name evidence="2" type="ORF">A0J61_01870</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000064">
        <property type="protein sequence ID" value="OBZ90101.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NLS1"/>
    <dbReference type="InParanoid" id="A0A1C7NLS1"/>
    <dbReference type="OrthoDB" id="17798at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1482"/>
            <end position="1510"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1501"/>
            <end position="1510"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ90101.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="2302" mass="261213" checksum="9EC582763628F873" modified="2016-11-30" version="1">MPSVSSLKRAFAMASTVEERELALKKHATSNTDDELYFQGLIILQKLHIEMMKQVGPSKLRDPSQTEKGLIAQMEKHLTLLSSSSFNPKRFDELNARFHLLVYPLEADKTIKFLKKELKIQSLNTFPEGVPNHSSTSVTPNQVSTAPSMLDPQLINGKMLLRKNLISSLHNQDSIQPTAFFEFSSIWDELSDKTKTRLLSEITRLPFEHVFDDKIIAFLTDCFKDAPLIAEVLSEKISFKTFTIEKMNRLMQTLPRITFLVNSFTNEYLLKLAPEDCPNLCNNSIWDDDQNVLKNYLDRLKAFANGLPDFYRPLKLMIAFHQLRVDIVRRDFSEDRFLRFISLNTNMPSDFSVSSQFSGLSTKQSSQAQPKTVEPSKLRVPILGPCDISAKNRDAVVKEYLIGLIEQNKLTKTVEDLGAHLDYTNFIKPLYAYVMITSSRTVNNEWVQMLGASSYEQLIEKKMVTFAPQTLHRLVKRKPLDPIVLSVRTKNIDRLSVRVYEIESENYARLSLRNPKAKDQIELEGILPTFEESIDFSNEPSLTIKTTTFTFGGQEGIASDVFKGRGIWVIEFVGGENQCRTIVQKGYLRHVIQETVAGHVLRIIDEENTVVKRAKVWYNNRYYESDESSNITIPYLPSDKEEQSSRIVLISSDDGFSESVAFTHAKENLMLETNFYVNSEMVYPNKKASVVVLPRLTLNGNSVPLSLLEDPSLTIDIGSSDSAKHSITCQNVGKDLKAIYYEFMVPDQLHILNLHFKARARKMDNTFESFHSEHIINYHSASDASGLPPSVHLTKSKEGRYLLHAFGKNGEIKNDCEISLRFKHTFLKEMICVPMKTNAEGYIDLGELKDICYFEHFSAHATYKQWKIQSTEDAVLPENLIVPAHTEFKIAYASNQTRPDCALYRLGYNSVLVDNMSKHIKKDISCLEIKGLPAGNYMLYLHRADGEIKKISCKIVDDQVKMEGRLWTGWIVNKKYFGKYDTDIVRKPLIISEIKLDDEKIDVHVKNNSAKTYIVATVSTFLPTSQDSLKYKLLSDRRLNIPTLQTAEFLNTQSVFLSDRRISDEYQYILNRSKSEKWAGSNLTKPSLLLYPKKTRDTLTNAKYLCTGHTLVSTAVDNTKQPSFNFNTKLSRKKPDTAQRFAAFAKMAYTNDYTNSIDASLAFLSSNLSTVVIAIDRDSNIATFDRNQLGVGGRLLQIVAISGDQLVAKQVDLTHDHTFHTKDLRQPVSANKRLIMAKAIKELMPAEALTLNTHDFAIIDSFEKLFDTIKVISSAGRMLIDEFEFLRSWPTFSLEKKLKTHEEKVCHELNLWLKKKDPQFFNAYVKPVIKNKVRKSFMDSYLLDEDLTPYCRDLYHFEKLNVVEKALLASTQPNQTLQATLRSFKDNLDDKQHNYQFDSIFESVLAGNNHSNTSTDDVGFNDNPPIPEASVFQVAAMEAPTSRSLFGSSAPIAIGSSSSAGFGSSSSSGLFGSKWAGSASSPVADAKEEEDISYTMSSENTSEEANFDGDGADDEALLELRKRSLQTSKKVYSFVEKTSEWKDAEYYDDNATFQLKQFWVDYLEYVHNNAPCFLPESFIYTLDSIQEIFYVLSLVDLPFASQVDWKVGSTDLGRDNSSSDFGVNICTYCHPVIVFYRTLVPCEQKEDSNHKDLILAQEFFVSDNSTTFYSEERVKIDPSTQNFSPQIEYGQHLTITNISSKPLDCQVTFQIPTGAVPVQMSSYCKSQAIRIEAYSTWHQVASIFYFPTHGEYASVPITVASASGDVFLGALESVIMHVIGDTESMLDHKDTTNPISMSWPSLATRGSDESVLTYLESYRKLNKLDLELVGWRMSDRKFAGQVFDILASRQYYCRSLAVYGVQHHFDDVIRDLIQFSGTDIMNNLGAVFESPLITKNEFGGSNLFILDYYPLLNARAHPFQSNAHEILNQEFYEQYDTFLEYLSLKNTPLTVPDLVMLTIYLLLQDHIGEAQVVLSQISSSSDQNIDCQVQIDYLNAYLKTRIPIVNGQHQMQLLDLQFIKDISQKYKNFGSLKWRKMFSGLLNFVREVEQGELMFSAEDSSNMSIQPESLLEFSIDHLQKKLVVQYANIDTIDVKFYEMNIEAMFSSNPFMGVNSHSSKLETSFTWTKPNRSVTVELPKQSEATASMDQDSFDIIGAGQTGFLQTTEVPFENINKNLFIEIAGGNIKRYQVHFANKMHVHVSESFGVVRVMSQETKRPLAGAYVKVYIRLKQWGGVQFWKDGYTGLNGVFDYISVTSGNVLIGNQQLDLKTIMHDKVDKLSILVLSEEEGAIVKEVYPPYGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NLX7</accession>
    <name>A0A1C7NLX7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Nicotinamide riboside kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">NRK1</name>
        <name evidence="2" type="ORF">A0J61_01829</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000063">
        <property type="protein sequence ID" value="OBZ90122.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NLX7"/>
    <dbReference type="FunCoup" id="A0A1C7NLX7">
        <property type="interactions" value="280"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NLX7"/>
    <dbReference type="InParanoid" id="A0A1C7NLX7"/>
    <dbReference type="OrthoDB" id="10041966at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006083">
        <property type="entry name" value="PRK/URK"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10285">
        <property type="entry name" value="URIDINE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00485">
        <property type="entry name" value="PRK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00988">
        <property type="entry name" value="URIDINKINASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Phosphoribulokinase/uridine kinase" evidence="1">
        <location>
            <begin position="9"/>
            <end position="161"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ90122.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="234" mass="26570" checksum="4C1DA40E3D76A166" modified="2016-11-30" version="1">MVKPQVVTIGISGASCSGKTTLALLLKKLLKNVITINQDEFYKPDELIPKDEETGLANWDSPAAVDFDRLNEAILRAKADPFQLLTQPEKPLQNNHHGSDLLSLQDFCHLYDSLDNLKDIVFVIVEGFLLFCDQRVCSNLDNKFFCNASKEVLKERRESRDGYVTLQGYWVDPPGYFDQIVWPQFLKWNRHILDSEQRGPDVLLIPTDTTSAKDMTSFAIHVLEKKYAACNGFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NMG4</accession>
    <name>A0A1C7NMG4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">TBC1 domain family member 13</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">TBC1D13</name>
        <name evidence="3" type="ORF">A0J61_01646</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000055">
        <property type="protein sequence ID" value="OBZ90302.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NMG4"/>
    <dbReference type="FunCoup" id="A0A1C7NMG4">
        <property type="interactions" value="88"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NMG4"/>
    <dbReference type="InParanoid" id="A0A1C7NMG4"/>
    <dbReference type="OrthoDB" id="27140at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.270">
        <property type="entry name" value="putative rabgap domain of human tbc1 domain family member 14 like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.80">
        <property type="entry name" value="Ypt/Rab-GAP domain of gyp1p, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000195">
        <property type="entry name" value="Rab-GAP-TBC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035969">
        <property type="entry name" value="Rab-GAP_TBC_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22957:SF27">
        <property type="entry name" value="TBC1 DOMAIN FAMILY MEMBER 13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22957">
        <property type="entry name" value="TBC1 DOMAIN FAMILY MEMBER GTPASE-ACTIVATING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00566">
        <property type="entry name" value="RabGAP-TBC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00164">
        <property type="entry name" value="TBC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47923">
        <property type="entry name" value="Ypt/Rab-GAP domain of gyp1p"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50086">
        <property type="entry name" value="TBC_RABGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rab-GAP TBC" evidence="2">
        <location>
            <begin position="55"/>
            <end position="512"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="727"/>
            <end position="747"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="761"/>
            <end position="796"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="728"/>
            <end position="747"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ90302.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="824" mass="93333" checksum="EF96F3EF88A6A92A" modified="2016-11-30" version="1">MQVLKYFRSVLSVEDVGQDTSGEKWTPVIDMKLFREACFQGSDSIRSLQITCSIPDEPGLRSLAWKVLMGYLPPDKRMWANTLKTQRLNYYNWVRDLLEEPGEEPPSSDHPLSTEPGSKWAVWFQDNSILEQIDKDVRRTLPDFAFFQLHVPANPLNPLSPPPAAPSILEEDLNESDPLSATTIFEEGQPEKEPKTRRFSFGLMGRPRSSSAASRKSLKLMNNTSNASVSISPAHNPLTTSVATSVSASNGHVISKRARSNSRSSVRSFSSGIIESGTDIISTPRNIVKKLSTAFTSKNSSGFVPKFSSGNMRKPLLEPICPYIPTRRSLFRRIAHLNEEIGNREHQVNGTKHIIGKQAIDADRQVMDYHWEAIERILFIYAKLNPGVGYVQGMNEILAPIYYVFTAKAAEDDPESQAYAEADTFFVFTTLISDTRDHFVRSLDQDASTGINATMWRMSQRLAWFDRPLFRHLSMKDIKEQYYAFRWITVLCSQEWDLPDVIRLWDSVLADRGMQEGLEEGRFEFLLDFAVAMLICIRQELIEGDFADNMRILQNYPIDDMQVVMNSAYSIREARLQAISSGRIIPGVNDRRSNGMINMDYSDTSSISSTGSGSRLKKLRDTTDMARASLDSLRKGSKESLDELFKRGLYIARNTSEELDRKRASTGDMTRSLSQRLGFANSLASKMKRTSSLRSSHSEQKDIEEQIHQDWLLANQLHATENNQYYHTQPNTRTSSPSSNSNQPRTNSLINRFSQFVSSKPVAPYKHHSLPQNKQDNTTKKAISPYPQSPVLSNPLQNKQDREQLANNLNVRRTVVGAYDRGYV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NML4</accession>
    <name>A0A1C7NML4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Transcriptional regulator prz1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">prz1_0</name>
        <name evidence="13" type="ORF">A0J61_01840</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the krueppel C2H2-type zinc-finger protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000063">
        <property type="protein sequence ID" value="OBZ90119.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NML4"/>
    <dbReference type="STRING" id="101091.A0A1C7NML4"/>
    <dbReference type="InParanoid" id="A0A1C7NML4"/>
    <dbReference type="OrthoDB" id="8922241at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000690">
        <property type="entry name" value="Zinc finger protein 354C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:001156">
        <property type="entry name" value="Zinc finger protein 407"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23235">
        <property type="entry name" value="KRUEPPEL-LIKE TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23235:SF120">
        <property type="entry name" value="KRUPPEL-LIKE FACTOR 15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="9" id="KW-0804">Transcription</keyword>
    <keyword evidence="7" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <keyword evidence="5 11" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="12">
        <location>
            <begin position="117"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="12">
        <location>
            <begin position="145"/>
            <end position="172"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="OBZ90119.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="190" mass="21713" checksum="CD30DCBB68EDA2A4" modified="2016-11-30" version="1">MYQGLSYFEPYPINVTKRDDFSIYSPFPLEHQESLLLATGFCPPLQDTRYIDVLNDPLAYQFTSPPMNQSSCSSSPSIDFHSLMTVPLESTTPDMWPAELPTVKIPVRQDNSNPKPFACHLCTRCFARKHDLQRHIRVHTGAKPYSCLSCSKAFARTDALKRHLRVEDSCRLSPVIQAMKNTGSRRYRNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NML6</accession>
    <name>A0A1C7NML6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_01624</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000054">
        <property type="protein sequence ID" value="OBZ90327.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NML6"/>
    <dbReference type="InParanoid" id="A0A1C7NML6"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ90327.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="82" mass="9083" checksum="33FB59569A422057" modified="2016-11-30" version="1">MIARLINSTNLASSKAGPIQADSRCNYTCGIQCYSPRTAFINIVEKRCQFGVYSVFSLDSHNLLDIQRLETVKTETPPICAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NN67</accession>
    <name>A0A1C7NN67_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Conserved oligomeric Golgi complex subunit 7</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Component of oligomeric Golgi complex 7</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">A0J61_01373</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Golgi apparatus membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the COG7 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000043">
        <property type="protein sequence ID" value="OBZ90573.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NN67"/>
    <dbReference type="STRING" id="101091.A0A1C7NN67"/>
    <dbReference type="InParanoid" id="A0A1C7NN67"/>
    <dbReference type="OrthoDB" id="249612at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017119">
        <property type="term" value="C:Golgi transport complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007030">
        <property type="term" value="P:Golgi organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006890">
        <property type="term" value="P:retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019335">
        <property type="entry name" value="COG7"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21443">
        <property type="entry name" value="CONSERVED OLIGOMERIC GOLGI COMPLEX COMPONENT 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21443:SF0">
        <property type="entry name" value="CONSERVED OLIGOMERIC GOLGI COMPLEX SUBUNIT 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10191">
        <property type="entry name" value="COG7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0653">Protein transport</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="147"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="147"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="167"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="178"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="249"/>
            <end position="273"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004395"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005831"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00020984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00031345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OBZ90573.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="296" mass="34088" checksum="F15F7E1445176A6D" modified="2016-11-30" version="1">MSAVVVNEKDFADPNFDPKKWINTVLKVNSINTSDDAKATEEDEESTDMTMLTTRLQLMSESTSQEFDRLSTQVVKSMPHVLYDLKMLSDNAKLVQNRIEEVRNNLSLVEDDTKIALEKLNRSHTVKTHMEECRIILLEESNHLEKLKEEEERKRQQEEAERKAIEEAAAAAVAAKAKALEEENEKKRQIEAEKEEEMRRRRKEEQEKEEKEKDEREAARAPSPEIDGDALEYGHVQLPPLRQPPPRQHTFQQIQKQTATSSDHNDGYLQQISGSVSPQVSSVFKKIGVPLDKLWQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NNE8</accession>
    <name>A0A1C7NNE8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Zinc finger protein ZIC 4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">Zic4</name>
        <name evidence="12" type="ORF">A0J61_01313</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the GLI C2H2-type zinc-finger protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000040">
        <property type="protein sequence ID" value="OBZ90641.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NNE8"/>
    <dbReference type="STRING" id="101091.A0A1C7NNE8"/>
    <dbReference type="InParanoid" id="A0A1C7NNE8"/>
    <dbReference type="OrthoDB" id="654211at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:002343">
        <property type="entry name" value="Zinc finger protein 33A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043359">
        <property type="entry name" value="GLI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056436">
        <property type="entry name" value="Znf-C2H2_ZIC1-5/GLI1-3-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45718:SF8">
        <property type="entry name" value="GLIS FAMILY ZINC FINGER 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45718">
        <property type="entry name" value="TRANSCRIPTIONAL ACTIVATOR CUBITUS INTERRUPTUS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23561">
        <property type="entry name" value="zf-C2H2_15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <keyword evidence="5 9" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="11">
        <location>
            <begin position="236"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="11">
        <location>
            <begin position="269"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="11">
        <location>
            <begin position="299"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="373"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="373"/>
            <end position="387"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010831"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="OBZ90641.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="447" mass="50039" checksum="EAB17C553D549F32" modified="2016-11-30" version="1">MDFTDLSMQEPSAYTPPFEMKDDMPILSYPSLTQTVTQPFMPSPPCSVPDQQQLLPFYNTNNMNSINIPHENIESSALDMNNQYQTNGILPIRYNNTHLDLNSNEINQQSNFTIVNEAAVIQQQSNDAQDNSKLLHHGTSTKAVDPKQFQDMSREELIARLVILEKEKKPTSEEPETDKATTNKAGAITIVIDEEELIVEQTKTCLWVGCGEKFDDLQSLTTHIGEVHVGGGKPTYRCEWEKCPRISKPFTKRHKMFNHLRTHTGERPFACPKPDCNKKFSRPDSLTTHIKTHSSIRPFICKYKNCGKAYYHARSLKKHEKLHETTITIDATGSLLLPPQLPLEAPAVSQTVTTVISALPAQQPPYFQAMTANSTVGQSPTPQSFDPNLSFYPPSTTQPPPSSLLPSYPNPNFNYPAPFDSNFIVDPMNPAMVPVYMPAASSCNPTQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NNX2</accession>
    <name>A0A1C7NNX2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">NAD(P)-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_02983</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000121">
        <property type="protein sequence ID" value="OBZ88964.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NNX2"/>
    <dbReference type="InParanoid" id="A0A1C7NNX2"/>
    <dbReference type="OrthoDB" id="10254221at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.25.10">
        <property type="entry name" value="UDP-galactose 4-epimerase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ88964.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="211" mass="23512" checksum="89B63E0BF4D2988A" modified="2016-11-30" version="1">MNDAEACFIIGGTSGVGAKPVTSFLTSNAFVTLLARDPEKAKTLFSDHIAHIRITKGSCNDLDDIKEGIQGHERPLLLVLDNQRPGKIKDSITTEKYEVVPFVSPDDINAVATVILQEDIQKHDTMSYDMTSDLLTSKQSASILSKLFGLDISYIQIAPVEKYYKLISNGAPAIDIVEAFKKLRKRRPLHILNRKPESVKQYLTSNQHCFH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NPF1</accession>
    <name>A0A1C7NPF1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Roadblock/LAMTOR2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_00965</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000026">
        <property type="protein sequence ID" value="OBZ90977.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NPF1"/>
    <dbReference type="InParanoid" id="A0A1C7NPF1"/>
    <dbReference type="OrthoDB" id="2386620at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ90977.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="98" mass="10749" checksum="500C7B18B914EDA8" modified="2016-11-30" version="1">MTDPTFEALASIPGHLSSFVASARDGQMLQSTADNNEKVALAAYQMVADASLLSQKTTGFQQDKLEHITVTFPNEYHTFTISNDLIYGIERVNHASTQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NPQ3</accession>
    <name>A0A1C7NPQ3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">A0J61_00982</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000026">
        <property type="protein sequence ID" value="OBZ90970.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NPQ3"/>
    <dbReference type="STRING" id="101091.A0A1C7NPQ3"/>
    <dbReference type="InParanoid" id="A0A1C7NPQ3"/>
    <dbReference type="OrthoDB" id="3176171at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005875">
        <property type="term" value="C:microtubule associated complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003777">
        <property type="term" value="F:microtubule motor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007018">
        <property type="term" value="P:microtubule-based movement"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007052">
        <property type="term" value="P:mitotic spindle organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051231">
        <property type="term" value="P:spindle elongation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027640">
        <property type="entry name" value="Kinesin-like_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47969">
        <property type="entry name" value="CHROMOSOME-ASSOCIATED KINESIN KIF4A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47969:SF15">
        <property type="entry name" value="CHROMOSOME-ASSOCIATED KINESIN KIF4A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25764">
        <property type="entry name" value="KIF21A_4th"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="482"/>
            <end position="505"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="269"/>
            <end position="430"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OBZ90970.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="505" mass="57870" checksum="CE07321B9F777A0B" modified="2016-11-30" version="1">MAIIFNHSIAHLQSNQLMEEEIKMIREEMEQIKSHSIQVSQELVETQSARDSLLLQLTQERPTEAHPLIQQYAQQIQDLKLEVTETRGKLNALCLEPSSPPTYPHYRITSSSLSTGRKKRPIIQRMRTSSFKKHPKVDPLRLIDKSTDETVAPISHGIPLEEKTELDPVLSIMPSTSLYHDELEALAVPSWSDMPKTSSVASSKRKSISLDSMWDDTDSSITTSRVDLTINEGQPHKSKSTALNEHKLKRQNKSLLKMLHQIQADLLVKRELVGQLERSEDQFSQLRTNYEERLTELREHLMETQRQRDDALEKASVRPPGLRENREAQEVRSQFEVKLKRLVSENQELKRKQAELTKTIQTARSKAEAAIQRLKSENDSLKSDRKQLNRALKHEIDRARDAAAADEREIQQLKRRLVLALDAKTKAEETVEAQHQVLRKRTEETSAAHLQLRQLTNALRKAANEGTFLNEAALDRIMEYAQTSKSNIRTTKQTRTRASSFASEP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NQ22</accession>
    <name>A0A1C7NQ22_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">DNA replication licensing factor MCM5</fullName>
            <ecNumber evidence="12">3.6.4.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">mcm5</name>
        <name evidence="14" type="ORF">A0J61_00805</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Acts as component of the MCM2-7 complex (MCM complex) which is the replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.12"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="12">Component of the MCM2-7 complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 12">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the MCM family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.12" evidence="12"/>
    <dbReference type="EMBL" id="LUGH01000020">
        <property type="protein sequence ID" value="OBZ91148.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NQ22"/>
    <dbReference type="FunCoup" id="A0A1C7NQ22">
        <property type="interactions" value="729"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NQ22"/>
    <dbReference type="InParanoid" id="A0A1C7NQ22"/>
    <dbReference type="OrthoDB" id="10036721at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000781">
        <property type="term" value="C:chromosome, telomeric region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071162">
        <property type="term" value="C:CMG complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042555">
        <property type="term" value="C:MCM complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005656">
        <property type="term" value="C:nuclear pre-replicative complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043596">
        <property type="term" value="C:nuclear replication fork"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043138">
        <property type="term" value="F:3'-5' DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003682">
        <property type="term" value="F:chromatin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003688">
        <property type="term" value="F:DNA replication origin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017116">
        <property type="term" value="F:single-stranded DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006270">
        <property type="term" value="P:DNA replication initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000727">
        <property type="term" value="P:double-strand break repair via break-induced replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006267">
        <property type="term" value="P:pre-replicative complex assembly involved in nuclear cell cycle DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006279">
        <property type="term" value="P:premeiotic DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030174">
        <property type="term" value="P:regulation of DNA-templated DNA replication initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031509">
        <property type="term" value="P:subtelomeric heterochromatin formation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006368">
        <property type="term" value="P:transcription elongation by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd17756">
        <property type="entry name" value="MCM5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000241">
        <property type="entry name" value="DNA helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.28.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1640.10">
        <property type="entry name" value="mini-chromosome maintenance (MCM) complex, chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031327">
        <property type="entry name" value="MCM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008048">
        <property type="entry name" value="MCM5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054125">
        <property type="entry name" value="MCM5_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018525">
        <property type="entry name" value="MCM_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001208">
        <property type="entry name" value="MCM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041562">
        <property type="entry name" value="MCM_lid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027925">
        <property type="entry name" value="MCM_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033762">
        <property type="entry name" value="MCM_OB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11630">
        <property type="entry name" value="DNA REPLICATION LICENSING FACTOR MCM FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11630:SF42">
        <property type="entry name" value="DNA REPLICATION LICENSING FACTOR MCM5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00493">
        <property type="entry name" value="MCM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21933">
        <property type="entry name" value="MCM5_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17855">
        <property type="entry name" value="MCM_lid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14551">
        <property type="entry name" value="MCM_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17207">
        <property type="entry name" value="MCM_OB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01657">
        <property type="entry name" value="MCMFAMILY"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01661">
        <property type="entry name" value="MCMPROTEIN5"/>
    </dbReference>
    <dbReference type="SMART" id="SM00350">
        <property type="entry name" value="MCM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00847">
        <property type="entry name" value="MCM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50051">
        <property type="entry name" value="MCM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10 12" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="3 12" id="KW-0235">DNA replication</keyword>
    <keyword evidence="8 11" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6 12" id="KW-0347">Helicase</keyword>
    <keyword evidence="5 12" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9 12" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MCM C-terminal AAA(+) ATPase" evidence="13">
        <location>
            <begin position="322"/>
            <end position="528"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU004070"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU368063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50051"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="OBZ91148.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="723" mass="80271" checksum="3AF14E4FA75340D2" modified="2016-11-30" version="1">MASFGWDQGQIYSTSVLPGEERVNSHSEITGLFYEFIQNFRLNNNYIYRDQLSQNLLTKQYFVEVDVNHLINYNADLANKLTNTPADYLPLFENAVKESAKRILFANPNSVSNMDVPDCQVTLKSDANVVQIRDLNSDYIGKLVRIPGIVIGASTLSSRATQVSAMCRNCRDIKIIPVTGGFSSITLPRKCDSKSPIGESNNCPMDPYVINHDKCRFVDSQVIKLQEAPDMVPVGDLPRHTILNADRWLTNRVVPGMRTVVMGIYSIFQNKAVKSSGAAAVRTPYIRIVGLQIDQHNNGRGKPHFTDAEEEEFIRMSRQPDLYETFASSLAPSIFGNNDIKKAITCLLFGGSKKVLPDGMRLRGDISVLLLGDPGTAKSQLLKFTEKVAPIAVYTSGKGSSAAGLTASVIRDPSTRDFYLEGGAMVLADGGVVCIDEFDKMRDEDRVAIHEAMEQQTISIAKAGITTILNSRTSVLAAANPVFGRYDDMKSAGENIDFQTTILSRFDMIFIVKDDHNENRDMSIARHVLNVHMNRQAQDAVMGEIDLDKMKAYVNYCKAKCAPRLTPAAAEKLSAHFVAIRKEVKDNERDNEIRSTIPITIRQLEAIIRISESLAKMTLSPYATEHHVEEALRLFKFSTMDAVQSGGADGMTRTEIMSEVQLIEKELQKRIPIGSQVPVAKIKADLSRNGYSEAAINRALTILNRRDVLLFRAQGKMAVRQSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NQF3</accession>
    <name>A0A1C7NQF3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">RNA helicase</fullName>
            <ecNumber evidence="1">3.6.4.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">prp22_1</name>
        <name evidence="11" type="ORF">A0J61_01305</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.13"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.13" evidence="1"/>
    <dbReference type="EMBL" id="LUGH01000039">
        <property type="protein sequence ID" value="OBZ90656.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NQF3"/>
    <dbReference type="STRING" id="101091.A0A1C7NQF3"/>
    <dbReference type="InParanoid" id="A0A1C7NQF3"/>
    <dbReference type="OrthoDB" id="10253254at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071013">
        <property type="term" value="C:catalytic step 2 spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000390">
        <property type="term" value="P:spliceosomal complex disassembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd17917">
        <property type="entry name" value="DEXHc_RHA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18791">
        <property type="entry name" value="SF2_C_RHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000615">
        <property type="entry name" value="pre-mRNA-splicing factor ATP-dependent RNA helicase DEAH7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000145">
        <property type="entry name" value="probable ATP-dependent RNA helicase DHX40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1080">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011709">
        <property type="entry name" value="DEAD-box_helicase_OB_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048333">
        <property type="entry name" value="HA2_WH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007502">
        <property type="entry name" value="Helicase-assoc_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18934">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18934:SF85">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE DHX8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21010">
        <property type="entry name" value="HA2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07717">
        <property type="entry name" value="OB_NTP_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04408">
        <property type="entry name" value="WHD_HA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00847">
        <property type="entry name" value="HA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 11" id="KW-0347">Helicase</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="9">
        <location>
            <begin position="24"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="10">
        <location>
            <begin position="215"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="562"/>
            <end position="590"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="699"/>
            <end position="735"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="566"/>
            <end position="576"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="577"/>
            <end position="586"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="706"/>
            <end position="735"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="OBZ90656.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="753" mass="86243" checksum="ADA4838C8FB55799" modified="2016-11-30" version="1">MSKRDRIREQRNSLPTFEYRQDLVDAIREYSILVVIGETGSGKTTQVPQYILEEIPEIKMIGVTQPRRIAAMTVAKRVSEEQDVRLGNTVGYTIRFDDHTSSSTRLKYMTDGILLREATMDPYLKHYDCIVIDEAHERTLETDVLFGLLKQTHRLRPELKILIMSATLDVAKFSDFFDECPIFEIPGRTFPVEVIYPPENIKLATLKSAMVDRAVETAWHIHTKEPTGDILVFLTGQQDIERACKAFAEQSRTCNYQKQVKYHDQVRDAVVYPLYASLEVFDQKAVFELPREGDRKVVFATNVAQTSVTIPGIRYVVDSGFVKEKSFDPSTGMDALLVTEISQAAAVQRAGRAGRTAPGKAYRLYGEESFYSMIPDTIPEIQRSSLVSTVLALKKMNIVDVLNFEFIDPPDEQLVRNALKQLYLLGAIDEEGKITRLGEQMNSFPLSPSLARVLLASVKLHCSHEALTIVSLLASDMEIFKTPSRARQEELVEAEEARHKLSHPTGDHMTLLNIYYEWKRHDKSRDWCKKQYLNHKVLETASHVRSQLVQVMDKLELPLTRAPTIQRKKKSSKSKRRIGENDRGESPDPVPILQSFLAGYFTNVANKSPHRAVFSHYAPDQHLASSDSYVNSTELVALHLHPLCALDRNHYADIEWVLYTHITYTNKAVMKGVSKILWDWVKHGQDRIKKLPLTRLNGEAQPNVEETDRAAEDKQEQIEKEKEEQDKQESKKRRAEEIELIRQRALARRRQRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NSE2</accession>
    <name>A0A1C7NSE2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Autophagy-related protein 3</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9 10">Autophagy-related E2-like conjugation enzyme ATG3</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="primary">atg3</name>
        <name evidence="11" type="ORF">A0J61_01673</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ATG3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000056">
        <property type="protein sequence ID" value="OBZ90264.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NSE2"/>
    <dbReference type="FunCoup" id="A0A1C7NSE2">
        <property type="interactions" value="733"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NSE2"/>
    <dbReference type="InParanoid" id="A0A1C7NSE2"/>
    <dbReference type="OrthoDB" id="1584384at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061908">
        <property type="term" value="C:phagophore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000407">
        <property type="term" value="C:phagophore assembly site"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019776">
        <property type="term" value="F:Atg8-family ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000045">
        <property type="term" value="P:autophagosome assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000422">
        <property type="term" value="P:autophagy of mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061723">
        <property type="term" value="P:glycophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034727">
        <property type="term" value="P:piecemeal microautophagy of the nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006612">
        <property type="term" value="P:protein targeting to membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1460.50:FF:000007">
        <property type="entry name" value="Autophagy-related protein 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1460.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007135">
        <property type="entry name" value="Atg3/Atg10"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12866">
        <property type="entry name" value="UBIQUITIN-LIKE-CONJUGATING ENZYME ATG3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12866:SF2">
        <property type="entry name" value="UBIQUITIN-LIKE-CONJUGATING ENZYME ATG3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03987">
        <property type="entry name" value="Autophagy_act_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0072">Autophagy</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0653">Protein transport</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <keyword evidence="6" id="KW-0833">Ubl conjugation pathway</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007683"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00018067"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00032144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00033139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="OBZ90264.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="307" mass="35621" checksum="A1347A0E01732AFE" modified="2016-11-30" version="1">MFSNFQKMRDYLAPVLKNSKFKETGCITPEEFVAAGEFLVYKCPTWHWEAGLDNKKRDYLPSDKQFLVTRNVPCIRRARQMEYTEDDSETQIKDENNDLDEDWMFTHSTRVTKTMEEIAQTIMTEEEEEAEIRKGLEKLNVDDIPDLDDIPDMDDIPDMDDQVQEEEDPAVQETNDKVLQVRTYDVFITYDKYYQTPRIWLFGYDEERRPLTSAQVFEDVSPDYVKKTVTIETHPHLSLSLASIHPCKHAEVMKKIIERMGDGQKAGVGATEEGGEGGIRVDQYLIIFLKFMSSVIPTIDYDHTISA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NUX8</accession>
    <name>A0A1C7NUX8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Apoptosis-inducing factor 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">AIFM2_0</name>
        <name evidence="6" type="ORF">A0J61_00629</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the FAD-dependent oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000015">
        <property type="protein sequence ID" value="OBZ91294.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NUX8"/>
    <dbReference type="STRING" id="101091.A0A1C7NUX8"/>
    <dbReference type="InParanoid" id="A0A1C7NUX8"/>
    <dbReference type="OrthoDB" id="202203at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004174">
        <property type="term" value="F:electron-transferring-flavoprotein dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023753">
        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43735">
        <property type="entry name" value="APOPTOSIS-INDUCING FACTOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43735:SF3">
        <property type="entry name" value="FERROPTOSIS SUPPRESSOR PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00368">
        <property type="entry name" value="FADPNR"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00469">
        <property type="entry name" value="PNDRDTASEII"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD/NAD(P)-binding" evidence="5">
        <location>
            <begin position="9"/>
            <end position="307"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006442"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF07992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OBZ91294.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="412" mass="45927" checksum="735C3AE65F895118" modified="2016-11-30" version="1">MSKSTKNIKLVVLGGGAAGLLIAMELSNTEYLSITLVDSKSFFEYTPGLCSVLYEATDRQFEKHFNEITFDYEPFLKSYQVDFVLGKVESIGDKKVQMSDKSSIDYDYLVICTGSSYADPWKVGSSDNESSTMDAHTRLESLRQHRTKFHAAQDILCIGGGPVGAELVTEVAYRMPDKRIVLVDSNDTVLSKAPNGIGKQAQIIINATPSIRSIMNEHASEKKEEPMSPKRIFETDKSHTRIETDLVYNCIGVTPNSDFLPKAWLDEKKQVIVDETLQVTGTHNVFAVGDVCSINEPKMFYTAHMQAVHFVKNLRRLLSNMTIQDLLPYQGAHVNMVISMGPHYAVGSISGVPFYGWPFNVKKGSRVAAVAKYFIERITMNDFGLKIPVNNLLYYTQTKNHGGLLPRQLAPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NVB5</accession>
    <name>A0A1C7NVB5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">PROP1-like PPR domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">A0J61_00551</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000012">
        <property type="protein sequence ID" value="OBZ91424.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NVB5"/>
    <dbReference type="FunCoup" id="A0A1C7NVB5">
        <property type="interactions" value="186"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NVB5"/>
    <dbReference type="InParanoid" id="A0A1C7NVB5"/>
    <dbReference type="OrthoDB" id="407658at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007005">
        <property type="term" value="P:mitochondrion organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006396">
        <property type="term" value="P:RNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051114">
        <property type="entry name" value="Mito_RNA_Proc_CCM1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002885">
        <property type="entry name" value="PPR_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033443">
        <property type="entry name" value="PROP1-like_PPR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00756">
        <property type="entry name" value="PPR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47934:SF6">
        <property type="entry name" value="MITOCHONDRIAL GROUP I INTRON SPLICING FACTOR CCM1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47934">
        <property type="entry name" value="PENTATRICOPEPTIDE REPEAT-CONTAINING PROTEIN PET309, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13812">
        <property type="entry name" value="PPR_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17177">
        <property type="entry name" value="PPR_long"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51375">
        <property type="entry name" value="PPR"/>
        <property type="match status" value="5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="PPR" evidence="2">
        <location>
            <begin position="241"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="domain" description="PROP1-like PPR" evidence="3">
        <location>
            <begin position="331"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="repeat" description="PPR" evidence="2">
        <location>
            <begin position="338"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="repeat" description="PPR" evidence="2">
        <location>
            <begin position="410"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="repeat" description="PPR" evidence="2">
        <location>
            <begin position="554"/>
            <end position="588"/>
        </location>
    </feature>
    <feature type="repeat" description="PPR" evidence="2">
        <location>
            <begin position="589"/>
            <end position="623"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00708"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF17177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OBZ91424.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="678" mass="78054" checksum="C8206259AC9E0A50" modified="2016-11-30" version="1">MFRTTRALLVYASKAANKPKTSFCLLNSNRAISQPICRTFSSAVDPEINNQPTLDLYKESTVGDTPQEKKALWENYVQRIESNDPTLTAKDFMDISRVVLKDKTSGLTSRITRTQHILTQVHLRLDQEGFDQVFVVGCNILMNYYITLGDLKSARFVFKGLSQSQTKPSTTSILTIINGIGRHGTKGDLHQFIKQLGGLDLFPNDNQTIYIRLINEFRRLNDYNSCGFYFAEMSKRGLDSDEESYVNMFKVYRDSQQPDSAYRMFQYMMKKGVEPTVRSYGVLIPLLMQTSQTKIKAEKLFKQARASGIYLNTSIYLAMNWDPMESLEEMKRTNTEVTTRDYNTCLAAYVKQNKFAEALNVFDFMKREGALMDRYTYGIVIDVLSKDPKTPTDVVFDLYNEMKTRNVGFDAVIYTSLMTACTWSHHFDRALSLLEDMHFYKVKPNQHTFNAILGVLASRPEAFAPDLNRARLIWSKMTSLGIAPETRTFNLYLSIMSKQVEPARPVEQAQSGWSDEVLWENQDESSEYVSPTVKEILRTYRYMRRHEDESIRPDFVTYSIIINSLITAGQLRSAMRVYDDAKLKRAQLPITVYNGIMNALQDAGKISESMNIWHDMRLNSILPDSQTYEIVLENCEQLGLMDSLKSIRDQRKLDFDRLAALEKKREERLAKRKTPSLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NWM7</accession>
    <name>A0A1C7NWM7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 14">Uroporphyrinogen decarboxylase</fullName>
            <ecNumber evidence="4 14">4.1.1.37</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="primary">urod</name>
        <name evidence="18" type="ORF">A0J61_00116</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18 19">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">Catalyzes the sequential decarboxylation of four acetate groups of uroporphyrinogen-III (octacarboxyporphyrin) to yield coproporphyrinogen-III (tetracarboxyporphyrin) with the formation of intermediate hepta-, hexa- and penta-carboxylate porphyrinogens in the heme biosynthesis pathway. Acts on a number of porphyrinogens, but only coproporphyrinogen III can ultimately be converted to heme.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>uroporphyrinogen I + 4 H(+) = coproporphyrinogen I + 4 CO2</text>
            <dbReference type="Rhea" id="RHEA:31239"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:62626"/>
            <dbReference type="ChEBI" id="CHEBI:62631"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11 14">
            <text>uroporphyrinogen III + 4 H(+) = coproporphyrinogen III + 4 CO2</text>
            <dbReference type="Rhea" id="RHEA:19865"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:57308"/>
            <dbReference type="ChEBI" id="CHEBI:57309"/>
            <dbReference type="EC" id="4.1.1.37"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 14">Porphyrin-containing compound metabolism; protoporphyrin-IX biosynthesis; coproporphyrinogen-III from 5-aminolevulinate: step 4/4.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 15">Belongs to the uroporphyrinogen decarboxylase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.1.1.37" evidence="4 14"/>
    <dbReference type="EMBL" id="LUGH01000002">
        <property type="protein sequence ID" value="OBZ91854.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NWM7"/>
    <dbReference type="FunCoup" id="A0A1C7NWM7">
        <property type="interactions" value="642"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NWM7"/>
    <dbReference type="InParanoid" id="A0A1C7NWM7"/>
    <dbReference type="OrthoDB" id="339900at2759"/>
    <dbReference type="UniPathway" id="UPA00251">
        <property type="reaction ID" value="UER00321"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004853">
        <property type="term" value="F:uroporphyrinogen decarboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006782">
        <property type="term" value="P:protoporphyrinogen IX biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd00717">
        <property type="entry name" value="URO-D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.210:FF:000004">
        <property type="entry name" value="Uroporphyrinogen decarboxylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.210">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00218">
        <property type="entry name" value="URO_D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038071">
        <property type="entry name" value="UROD/MetE-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006361">
        <property type="entry name" value="Uroporphyrinogen_deCO2ase_HemE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000257">
        <property type="entry name" value="Uroporphyrinogen_deCOase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01464">
        <property type="entry name" value="hemE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21091">
        <property type="entry name" value="METHYLTETRAHYDROFOLATE:HOMOCYSTEINE METHYLTRANSFERASE RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21091:SF169">
        <property type="entry name" value="UROPORPHYRINOGEN DECARBOXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01208">
        <property type="entry name" value="URO-D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51726">
        <property type="entry name" value="UROD/MetE-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00906">
        <property type="entry name" value="UROD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00907">
        <property type="entry name" value="UROD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7 14" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="8" id="KW-0350">Heme biosynthesis</keyword>
    <keyword evidence="9 14" id="KW-0456">Lyase</keyword>
    <keyword evidence="10 14" id="KW-0627">Porphyrin biosynthesis</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Uroporphyrinogen decarboxylase (URO-D)" evidence="16">
        <location>
            <begin position="30"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="domain" description="Uroporphyrinogen decarboxylase (URO-D)" evidence="17">
        <location>
            <begin position="152"/>
            <end position="168"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004804"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009935"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00014308"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00048033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00052550"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00058098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU000554"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="RuleBase" id="RU004169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS00906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS00907"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="OBZ91854.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="367" mass="41114" checksum="7D5288F6F4446183" modified="2016-11-30" version="1">MATYKAENFPALQNDLILRVSRGEKVERAPVWIMRQAGRYLPEFHEIRKEHSFFEVCRTPELACELTLQPIRRYGKLLDASIIFSDILVIPQAMGLEVNMVAGRGPVFSAPLETPDDLSRLTENVDVDKELGYVYQAITLTRHKLEGRVPLFGFVGAPWTLMAYMIEGGGSKTLSKAKSWLWKYPKESHALLQRITDIAVEFLVGQVRAGAQMLQVFESWGGELSPYDFKEYSLPYIRQISTQVKERLAKEGLDAVPMTVFAKGSWYALADLSESNYEVVSLDWTIDPAYARQVTGDKVALQGNMDPSALYGGSGAIREIATRMVHAFGKDSKHIVNLGHGILPTVDPEALKVYLETVQQVSADIRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MNR6</accession>
    <name>A0A1C7MNR6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">CCHC-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_11852</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01002587">
        <property type="protein sequence ID" value="OBZ78521.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MNR6"/>
    <dbReference type="InParanoid" id="A0A1C7MNR6"/>
    <dbReference type="OrthoDB" id="2235777at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.60.10">
        <property type="entry name" value="Zinc finger, CCHC-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001878">
        <property type="entry name" value="Znf_CCHC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036875">
        <property type="entry name" value="Znf_CCHC_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00098">
        <property type="entry name" value="zf-CCHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00343">
        <property type="entry name" value="ZnF_C2HC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57756">
        <property type="entry name" value="Retrovirus zinc finger-like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50158">
        <property type="entry name" value="ZF_CCHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="CCHC-type" evidence="2">
        <location>
            <begin position="24"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ78521.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="95" mass="10915" checksum="11958C63FCC55E4F" modified="2016-11-30" version="1" fragment="single">MSSLVAELVKSSNNKISKTTKRTCWNCNSTDHLTKDCQAPCKLCKENGHRHYECKLYKPNSSQRNKTQSESMLIEELYLSEKRNASEIDEDSTNI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MTB5</accession>
    <name>A0A1C7MTB5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_11840</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01002569">
        <property type="protein sequence ID" value="OBZ80111.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MTB5"/>
    <dbReference type="InParanoid" id="A0A1C7MTB5"/>
    <dbReference type="OrthoDB" id="2275967at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="186"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ80111.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="186" mass="20815" checksum="3E9DF3BDDFF3F736" modified="2016-11-30" version="1" fragment="single">MEKCSKKRDNIAALQGKEAECAISRQLITIIANTCKKKPSISYSETVYNVKLIFPSLYAVLDWLEDHPTSPVFIPGEEELLSMSKQFTKIKKYSRRNIYKADGVVRLGDDVEVLLVETIGSFGLDNPGKLSFDNSKAMFGLLAMLKTIVNKYSCASMSSFKKLKLLFLQPGSDALRLWTLAYSKNG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MUR9</accession>
    <name>A0A1C7MUR9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">ATP-dependent DNA helicase</fullName>
            <ecNumber evidence="1">5.6.2.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_11340</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="5.6.2.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the helicase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.6.2.3" evidence="1"/>
    <dbReference type="EMBL" id="LUGH01001924">
        <property type="protein sequence ID" value="OBZ80611.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MUR9"/>
    <dbReference type="STRING" id="101091.A0A1C7MUR9"/>
    <dbReference type="InParanoid" id="A0A1C7MUR9"/>
    <dbReference type="OrthoDB" id="5860629at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043139">
        <property type="term" value="F:5'-3' DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000723">
        <property type="term" value="P:telomere maintenance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010285">
        <property type="entry name" value="DNA_helicase_pif1-like_DEAD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10492">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10492:SF100">
        <property type="entry name" value="ATP-DEPENDENT DNA HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05970">
        <property type="entry name" value="PIF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0227">DNA damage</keyword>
    <keyword evidence="1" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="1" id="KW-0234">DNA repair</keyword>
    <keyword evidence="1" id="KW-0347">Helicase</keyword>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA helicase Pif1-like DEAD-box helicase" evidence="2">
        <location>
            <begin position="2"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU363044"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF05970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ80611.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="109" mass="11811" checksum="DDE0877FEC9B3FA3" modified="2016-11-30" version="1" fragment="single">VRRTSNIALSVPVGGTAALLLKGGRTAHSRFKIPLDCSTTLICLMSPSSSAAALVAMSAIIVWDEASMVSRDILETVDRLFRDFIKLRDQRLANVPFGGKLIMFGGDFR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MUV3</accession>
    <name>A0A1C7MUV3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">ERAD-associated E3 ubiquitin-protein ligase component HRD3A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">HRD3A</name>
        <name evidence="2" type="ORF">A0J61_11404</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001995">
        <property type="protein sequence ID" value="OBZ80547.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MUV3"/>
    <dbReference type="STRING" id="101091.A0A1C7MUV3"/>
    <dbReference type="InParanoid" id="A0A1C7MUV3"/>
    <dbReference type="OrthoDB" id="272077at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052945">
        <property type="entry name" value="Mitotic_Regulator"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006597">
        <property type="entry name" value="Sel1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43628">
        <property type="entry name" value="ACTIVATOR OF C KINASE PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43628:SF1">
        <property type="entry name" value="CHITIN SYNTHASE REGULATORY FACTOR 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08238">
        <property type="entry name" value="Sel1"/>
        <property type="match status" value="10"/>
    </dbReference>
    <dbReference type="SMART" id="SM00671">
        <property type="entry name" value="SEL1"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81901">
        <property type="entry name" value="HCP-like"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="111"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="475"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ80547.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="475" mass="53576" checksum="80CBA61EA02AEA05" modified="2016-11-30" version="1" fragment="single">SLHESGFGNIIVQPNVKKALEYYIQAATKQHEPSMMKVGEILGGMLGCHEEAIHWFKKTSRSYPENVMAKVMLISYELQGFDCGLSVESNKDTSNFKLLRHIVAQYNTDESNQEDLLQDKEEEEEEENPLSRRRNELCSKKNGMGHAYYILGQCYEFGRGTSVDLLASIDAYEIAVSSCDHIDAMWRLGMVYSYRFDDDSSALDWFRKASEKARHRDSHYQLGLFHLRGRGGLEINLAAAKRYFTKAAEQNHAMATYELARILWTIDSSHLKAYELFERAAQQNVPGALCHLGHFSYTGLYYRSICVVEKDLQKAFAYYSEAAQAGDPIAALMVGSHFEDKGNLDRALQWYESSYRLGGGGLAELAIGKIKHCMSQTDPHAQEEAIAWFESAAADDMLKRQSVFSAHVMIALYHLNGWGNRDKDSQKGFQMLLKIANMGGTEVFSLLAECYKEGIGKEHHQDNTSNLEKAASDEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MUX2</accession>
    <name>A0A1C7MUX2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_11317</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001902">
        <property type="protein sequence ID" value="OBZ80633.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MUX2"/>
    <dbReference type="InParanoid" id="A0A1C7MUX2"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="11"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ80633.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="56" mass="6735" checksum="38102AC631A7FA2E" modified="2016-11-30" version="1" fragment="single">HLDTKRKKKTDRLARADVEAERRQKEAEVTEQANRMRAKTRSDEISRNNLVRRTRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MV18</accession>
    <name>A0A1C7MV18_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Helitron helicase-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_11343</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001929">
        <property type="protein sequence ID" value="OBZ80608.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MV18"/>
    <dbReference type="STRING" id="101091.A0A1C7MV18"/>
    <dbReference type="InParanoid" id="A0A1C7MV18"/>
    <dbReference type="OrthoDB" id="2278933at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025476">
        <property type="entry name" value="Helitron_helicase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45786:SF74">
        <property type="entry name" value="ATP-DEPENDENT DNA HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45786">
        <property type="entry name" value="DNA BINDING PROTEIN-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14214">
        <property type="entry name" value="Helitron_like_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helitron helicase-like" evidence="1">
        <location>
            <begin position="86"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="197"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF14214"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ80608.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="197" mass="22739" checksum="02CE25738512B408" modified="2016-11-30" version="1" fragment="single">MTQFVRENPEHVSDVSMVFKVDDDLDLRRYNAPTTSIEVGILILGGGRRQEDEDGKLQRISELSQMYDPMSYAILFPSGKRGWNKDCSSAELNRELQDAIAHDDTNASSLGRKVVLPSTFIGSPRHMAQIYYGSMSIVRRFRKPDYFITITYNPAWPEIKNELLFGQSAADRPDLCSRVFRLKFKELIKDFIRSMFW</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MVG5</accession>
    <name>A0A1C7MVG5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">ATP-dependent DNA helicase</fullName>
            <ecNumber evidence="1">5.6.2.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">pif1_3</name>
        <name evidence="4" type="ORF">A0J61_11194</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="5.6.2.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the helicase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.6.2.3" evidence="1"/>
    <dbReference type="EMBL" id="LUGH01001764">
        <property type="protein sequence ID" value="OBZ80757.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MVG5"/>
    <dbReference type="STRING" id="101091.A0A1C7MVG5"/>
    <dbReference type="InParanoid" id="A0A1C7MVG5"/>
    <dbReference type="OrthoDB" id="3691720at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043139">
        <property type="term" value="F:5'-3' DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000723">
        <property type="term" value="P:telomere maintenance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd18809">
        <property type="entry name" value="SF1_C_RecD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010285">
        <property type="entry name" value="DNA_helicase_pif1-like_DEAD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049163">
        <property type="entry name" value="Pif1-like_2B_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10492">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10492:SF57">
        <property type="entry name" value="ATP-DEPENDENT DNA HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05970">
        <property type="entry name" value="PIF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21530">
        <property type="entry name" value="Pif1_2B_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0227">DNA damage</keyword>
    <keyword evidence="1" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="1" id="KW-0234">DNA repair</keyword>
    <keyword evidence="1 4" id="KW-0347">Helicase</keyword>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA helicase Pif1-like DEAD-box helicase" evidence="2">
        <location>
            <begin position="6"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="domain" description="DNA helicase Pif1-like 2B" evidence="3">
        <location>
            <begin position="220"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="383"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU363044"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF05970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF21530"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OBZ80757.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="383" mass="43367" checksum="EBC68D748027D05A" modified="2016-11-30" version="1" fragment="single">MVQLVPKNSNLAKLLRKTSLLIWDKVPMQNKSCFEAVDRTLQDIRSNDTLFGGLPVILGGDFAQIPPVIKNGNRSSIVEASIKQSYIWSKVKMLHLKQNMRVRGTSAQDIHFKKWLYLISYNTFMQNPKIPLPEYISQTHSLEELISRVYPQRNPTEAIGNPSLLYKSAILTFKNDTVDLLNHKVFELMPGTSTTLISADKADYSEEENANNEVYRFSTEYLQTLNPGNFPPSKLTLKIGCIVMLLRNLNPQKGLCNGTRLIVKEIGQYVLKVAVLNDNNSNVEQIELIPRIELTTLEVDYPFVLVRKQFPVKLSFAMTINKSQGQSLSNVGIGLRISPFTHGQLYVAFSRSTNLQGIHVLRGSNQYNQITPIENIIYPELLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MVH0</accession>
    <name>A0A1C7MVH0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uracil catabolism protein 4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">URC4_3</name>
        <name evidence="1" type="ORF">A0J61_11119</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001691">
        <property type="protein sequence ID" value="OBZ80832.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MVH0"/>
    <dbReference type="InParanoid" id="A0A1C7MVH0"/>
    <dbReference type="OrthoDB" id="2153176at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012469">
        <property type="entry name" value="DUF1688"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31687">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31687:SF3">
        <property type="entry name" value="PROTEIN URG3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07958">
        <property type="entry name" value="DUF1688"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ80832.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="112" mass="12138" checksum="01CAC401D3B1417B" modified="2016-11-30" version="1">MTGLPEYRNGGLLVDYGLLTLKLEQAKRGGATQEGQLPAFEGSDPVIVEWRALTVTYLDKIKKEVEKKLGRTLSLAQVLEGGTWTAGREIAAKLRPEDGGPPIVIKSDGTIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MW13</accession>
    <name>A0A1C7MW13_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">ATP-dependent DNA helicase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_11333</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001917">
        <property type="protein sequence ID" value="OBZ80619.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MW13"/>
    <dbReference type="InParanoid" id="A0A1C7MW13"/>
    <dbReference type="OrthoDB" id="2285191at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ80619.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="121" mass="13760" checksum="55AEB0A5D3654C9B" modified="2016-11-30" version="1">MLNNTLIKTRHRNVAMGGIKSIFYGDVAQLLPVNPKEEPICKSGLFRYSRKYCLMEPVTQTEAGFIEILNKVRLCQFDESVIKYINSRAVLKSDIPNKSLRLYTTRQRVTAANSKDSDAMS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-06-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MW75</accession>
    <name>A0A1C7MW75_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_10814</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001416">
        <property type="protein sequence ID" value="OBZ81135.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MW75"/>
    <dbReference type="InParanoid" id="A0A1C7MW75"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ81135.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="89" mass="10107" checksum="71CF9427F6FF74CC" modified="2016-11-30" version="1">MESTTKELLTGPINEAEYTCWFLYPVLLQATLDCNVEIRLGDSCLGDNMSETESEADMTFYSKRLRIPICLVEVSGAPDEVDKQYYLND</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MX22</accession>
    <name>A0A1C7MX22_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">WD repeat domain phosphoinositide-interacting protein 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">wdr45b</name>
        <name evidence="4" type="ORF">A0J61_10578</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the WD repeat PROPPIN family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001245">
        <property type="protein sequence ID" value="OBZ81373.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MX22"/>
    <dbReference type="FunCoup" id="A0A1C7MX22">
        <property type="interactions" value="407"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7MX22"/>
    <dbReference type="InParanoid" id="A0A1C7MX22"/>
    <dbReference type="OrthoDB" id="1667587at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048720">
        <property type="entry name" value="PROPPIN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11227">
        <property type="entry name" value="WD-REPEAT PROTEIN INTERACTING WITH PHOSPHOINOSIDES WIPI -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21032">
        <property type="entry name" value="PROPPIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1" id="KW-0853">WD repeat</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00025740"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OBZ81373.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="408" mass="45220" checksum="2D2A7E397954EA64" modified="2016-11-30" version="1">MNLSKTSPTANDAPGLLYAGFNQDYGCFAVGLDTGFRVYNCEPLIEQARDESDEGGIAIVEMLYRTNYLALVGGGRNPRYPPNKVIIYDSMKGKPVLELEYKSEVRSVKLRRDRLTVILQNKVFVYHFSLPPQLLHTFETCDNERGLAAVSTSHNHAILVIPSRQKGHLQIVDLNSLGYYISVGESDSPFSPSLPAQDYSSNTTRRSINVSIISAHSGKLSCIALNADGSRCATSSDKGTLIRVFNTSTGTLLHELRRGMDRAEIYSIAFNQESTRLCVSSDKGTIHVFNLDPSVVTHIDHKPRGPTYGEVVVYPTQSPTSYGLTTTGNRGSALSFMKDLLPKYFSSEWSFAHAKIATESRCLVAFGTQKNSFTAICADGSCYKFYFDPRMGGECTRESFVRFLKREQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MXE6</accession>
    <name>A0A1C7MXE6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Transposon TX1 uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">YTX2_0</name>
        <name evidence="5" type="ORF">A0J61_10503</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001204">
        <property type="protein sequence ID" value="OBZ81448.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MXE6"/>
    <dbReference type="STRING" id="101091.A0A1C7MXE6"/>
    <dbReference type="InParanoid" id="A0A1C7MXE6"/>
    <dbReference type="OrthoDB" id="2212429at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01650">
        <property type="entry name" value="RT_nLTR_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.60.10">
        <property type="entry name" value="Zinc finger, CCHC-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043502">
        <property type="entry name" value="DNA/RNA_pol_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000477">
        <property type="entry name" value="RT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001878">
        <property type="entry name" value="Znf_CCHC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036875">
        <property type="entry name" value="Znf_CCHC_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19446">
        <property type="entry name" value="REVERSE TRANSCRIPTASES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00078">
        <property type="entry name" value="RVT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00098">
        <property type="entry name" value="zf-CCHC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00343">
        <property type="entry name" value="ZnF_C2HC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56672">
        <property type="entry name" value="DNA/RNA polymerases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57756">
        <property type="entry name" value="Retrovirus zinc finger-like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50878">
        <property type="entry name" value="RT_POL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50158">
        <property type="entry name" value="ZF_CCHC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="CCHC-type" evidence="3">
        <location>
            <begin position="3"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="domain" description="CCHC-type" evidence="3">
        <location>
            <begin position="122"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="domain" description="Reverse transcriptase" evidence="4">
        <location>
            <begin position="287"/>
            <end position="548"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="165"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="177"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="689"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OBZ81448.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="689" mass="77625" checksum="CCF8EB1C199E8955" modified="2016-11-30" version="1" fragment="single">FSCWTCGANGHMAASCPKDAPQKKAKVKAPVVPKLDFNFSERFSTSQTETSAFKSSIWHPDHGSNSVFIDMTGRKEFVADFFLLVAHQYPSRVGVLPQKVGNLRYAEICFDDDDDEVAKFSCWTCGANGHMAASCPKDAPQKKAKVKAPVVPKLDFNFSERHETTESLALKSGQPAFRDDATEESRSDSASMLRSANQFYQQLYTADPVDTAQLDEYLNEVSSMPRVKVDDHQSLLAPITIDDIIAVTAKVVSKQSSPGSDGFGYAYLYHLYRFPPLQHLVIQVYNDALLRCLFPTSWRDVRVQLLPKKGDLTLLRNWRPISLINCDAKIFPRILNARMKEVAPSVITPFQTGFMPGRFIATNGILVNMVMEHARRTQRDDVALLLDQEKAYDRVHPLYLRRTLLHLNFPLLLVDCLMNLFFGNKVRVNVNGFFSDEHILQDSAFQGFVFDQVASPSSPPTPEPLKALAYADDVCVFLANDTDFRLLQHHLARYGQVSNAKVNMHKTEAISLSGRPSSTWQSLLGSFEIHSWHDRISPQPLRYLGFPLRYLGFPLISSLSQRKLVKLQLLDSLQAKCDRFKDMNLALCGRATVVNTLPLADGFLNLPDDHWIVASRPTPLLLKYFFTIDESRNCFRSLHPPDRPRFPRLCAKLRLELLSPGISLQPRLLAAILHPPESLAPVTTQPFDT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MYS5</accession>
    <name>A0A1C7MYS5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Protein HID1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">HID1</name>
        <name evidence="2" type="ORF">A0J61_09876</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000961">
        <property type="protein sequence ID" value="OBZ82075.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MYS5"/>
    <dbReference type="FunCoup" id="A0A1C7MYS5">
        <property type="interactions" value="8"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7MYS5"/>
    <dbReference type="InParanoid" id="A0A1C7MYS5"/>
    <dbReference type="OrthoDB" id="432953at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005797">
        <property type="term" value="C:Golgi medial cisterna"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000138">
        <property type="term" value="C:Golgi trans cisterna"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026705">
        <property type="entry name" value="Hid-1/Ecm30"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21575">
        <property type="entry name" value="PROTEIN HID1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21575:SF12">
        <property type="entry name" value="PROTEIN HID1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12722">
        <property type="entry name" value="Hid1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="572"/>
            <end position="614"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="572"/>
            <end position="591"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="601"/>
            <end position="614"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ82075.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="739" mass="84374" checksum="E5155FD1A72EF05A" modified="2016-11-30" version="1">MGATDSKLAFRKGVFRLFEEKHIPTSADDYWTLFWTLPESVDDVYTLVSSTDIRKARDHAIENLETLIDKIMEHMDRLLQTTAPIPSIQLLNCCRVLTRIMPYIFESPECAEWEHKFFWTPDASKTNPLPRGEHLLSLTLQSLFLAGFTLPHTMSTAQSRVNFVIWETGVGSSTPIGSSRDNDLNRTEVLRLLTVLLSKSIYVTPAHLTTQEDRWLHYMVSKTERKVVLAFLCSMINTACKFNPMGWTAVPYNHIVFSDPREHLVTLCLRGLLIVLDYRPIIENEEHQQHEDEGKTQESVSENAFRYYLSKLHRAQDFQFSIDGIYRILSSPMQTLNSYLPGSSKRVRCHVEMMMLCWKLLEVNNRFRKYLIETERALDLMIVLLYYASENKLDPSQVGLVRMCSFILQTLSSDRTFSVKLNKPFDGHGALPVNIKIPNFHGTYADYLILTIFSLIASSRGALSTLYPAMIKTITNISPYLKHLSSTTSSKLVALFGSMSAPGFLLADEPNHLLAGYLLEAFNHIIQFQFSSKYNPHFIYAVLRSHRKFEKLAEFNLENGLIEIERQLKRQQEDNLQEGHHDLSEKAKGKLPESLSGGSSGINTPQRQPSVSSIGSMALPGAKNGFIPTDEWIQQWHSKLPLEIIMALIHELKSQLESQQSHEQLLEFLTNVSTDKLPPAHPVVIRKFQWSEPSVIWFRSMLWGQAYVASVSSYGPWNNTQVKLFHIKQPQPSSSIETS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MZ68</accession>
    <name>A0A1C7MZ68_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Oxysterol-binding C23B6.01c</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_09794</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the OSBP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000938">
        <property type="protein sequence ID" value="OBZ82160.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="FunCoup" id="A0A1C7MZ68">
        <property type="interactions" value="552"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7MZ68"/>
    <dbReference type="InParanoid" id="A0A1C7MZ68"/>
    <dbReference type="OrthoDB" id="14833at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032934">
        <property type="term" value="F:sterol binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.2720:FF:000001">
        <property type="entry name" value="Oxysterol-binding OBPalpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.2720">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.160.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.3490">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037239">
        <property type="entry name" value="OSBP_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000648">
        <property type="entry name" value="Oxysterol-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018494">
        <property type="entry name" value="Oxysterol-bd_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10972:SF102">
        <property type="entry name" value="OXYSTEROL-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10972">
        <property type="entry name" value="OXYSTEROL-BINDING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01237">
        <property type="entry name" value="Oxysterol_BP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144000">
        <property type="entry name" value="Oxysterol-binding protein-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01013">
        <property type="entry name" value="OSBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003844"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ82160.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="398" mass="45377" checksum="AFDBC82D68894834" modified="2016-11-30" version="1">MSNTTQNTSDNSNNTEELAEGSRSILLSIASQLTKGMDLHRVTLPTFVLEPRSMLERITDFMAHPELILPIPHIDDNTQRFISVVKWFLAGWHIKPKGVKKPYNPXLGEFFRCKYQYEDGTEAFYIAEQVSHHPPASAYFYTCPQHKVVITGDLRPKSRFYGNSVGSLMHGHIDFILPGRHNERYEVKMPNMYARGVLFGTMTLELGDASSVRCVSSDLICEMDFQTKGFFSGQCNSVVGKIKRESTQEVLYEISGQWSGELLIKKYVPDKSGSTIGGLLSLRGNTSSPEKSEVLVNVSQHQICPLLVSENQEEKESRRLWAGLTEGIMERNMDKATDEKFKVEDRERALRKEREAKNIQWVPRFFDVINGDEYKFKNIDSLNFDQPEEVTKTITALF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MZM1</accession>
    <name>A0A1C7MZM1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_11367</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001956">
        <property type="protein sequence ID" value="OBZ80584.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MZM1"/>
    <dbReference type="InParanoid" id="A0A1C7MZM1"/>
    <dbReference type="OrthoDB" id="10520647at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ80584.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="65" mass="7606" checksum="A7429D63FF226CD0" modified="2016-11-30" version="1">MYAKEDILDTRKFTTETFALLGRMVDVIVNKRLDQHNIAKLDLRQTLIELLEITDYAAQKSDCYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MZW7</accession>
    <name>A0A1C7MZW7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1 9">Mitogen-activated protein kinase</fullName>
            <ecNumber evidence="1 9">2.7.11.24</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">MKP1_0</name>
        <name evidence="11" type="ORF">A0J61_09504</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="13 9">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.24"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="9">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="activity regulation">
        <text evidence="9">Activated by threonine and tyrosine phosphorylation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.24" evidence="1 9"/>
    <dbReference type="EMBL" id="LUGH01000865">
        <property type="protein sequence ID" value="OBZ82445.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MZW7"/>
    <dbReference type="STRING" id="101091.A0A1C7MZW7"/>
    <dbReference type="InParanoid" id="A0A1C7MZW7"/>
    <dbReference type="OrthoDB" id="192887at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004707">
        <property type="term" value="F:MAP kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd07834">
        <property type="entry name" value="STKc_MAPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000040">
        <property type="entry name" value="Mitogen-activated protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003527">
        <property type="entry name" value="MAP_kinase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050117">
        <property type="entry name" value="MAPK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24055">
        <property type="entry name" value="MITOGEN-ACTIVATED PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01351">
        <property type="entry name" value="MAPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 9 11" id="KW-0418">Kinase</keyword>
    <keyword evidence="9" id="KW-0460">Magnesium</keyword>
    <keyword evidence="4 7 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 8" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3 9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="10">
        <location>
            <begin position="25"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="55"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012411"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU361165"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="OBZ82445.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="410" mass="46994" checksum="22FB7B69F8EA93A2" modified="2016-11-30" version="1">MEQHYITVPISRDNPQDVFTVNTKYRVIRRVGSGAYGTVCSAFDQQHQRFCAIKKMHRVFEKELVTKRCIREMKLLQLFSNHPRIIQLFDMDIVYGLDEVYLIFGCMDASLHDVIHSQQPLDTVHAQWFIYQTLSGLKYIHSANVVHRDLKPANILVNKDCDIRICDFGMARAFSQTNSMPYLTEYVTTRWYRAPEIMINSHNYSKAIDIWSAGCVFGEILGRKVLFQGRDHVDQLYKILGVLGLPNDISFWDPSEAVSAHIKNLCTTDGLPPPTEPVDFNAFFPSATPEAIELLKRLLHLDPAKRITAEEALKHPFVQPFSDSVEESLVPPYVDPQQYYIFEDVHNNSALKSMAIQEIEFFKHRMSQQELSESLLTNNTDGTITTAKRSHTAAVATTMRHFDSSSSWQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-06-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N0Z2</accession>
    <name>A0A1C7N0Z2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_09650</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000900">
        <property type="protein sequence ID" value="OBZ82299.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N0Z2"/>
    <dbReference type="InParanoid" id="A0A1C7N0Z2"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ82299.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="91" mass="10617" checksum="16C907CA954635CD" modified="2016-11-30" version="1">MKKKESKSLNEKIALEEKGSNGYSHQTNYSYLDHVFFKLLLQANIKTILLVYQIKHALKSNCTRVCLRPLFRQKKLVEHEVANGEVIQEQN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N1B5</accession>
    <name>A0A1C7N1B5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">U11/U12 small nuclear ribonucleoprotein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">SNRNP59</name>
        <name evidence="3" type="ORF">A0J61_09464</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000856">
        <property type="protein sequence ID" value="OBZ82486.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N1B5"/>
    <dbReference type="STRING" id="101091.A0A1C7N1B5"/>
    <dbReference type="InParanoid" id="A0A1C7N1B5"/>
    <dbReference type="OrthoDB" id="2289628at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005689">
        <property type="term" value="C:U12-type spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052831">
        <property type="entry name" value="Apoptosis_promoter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031974">
        <property type="entry name" value="PDCD7"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48190">
        <property type="entry name" value="PROGRAMMED CELL DEATH PROTEIN 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48190:SF2">
        <property type="entry name" value="PROGRAMMED CELL DEATH PROTEIN 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16021">
        <property type="entry name" value="PDCD7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="115"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="7"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="123"/>
            <end position="134"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ82486.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="271" mass="32199" checksum="5CFB7CDEC3AED469" modified="2016-11-30" version="1">MHKIMSLTETKRRLAEAIELYDNLKQEIDHKDLDAYADDEWHQFLSRLGYQTAQLIQTSKQLDDPHLLSLLKRKQAKLKRHSEWRKRHKKRARLHKLQEARRSERWVMETTMAVSMAPAHQQKSTEKETKEDNLKHKIKKASGILRQLILLRQLRRKRLEAKGHFFAESGNQFFDQVKAWHEQEEGKKNESTSDSLVVHPQDSWQHIKLDLNAYAYWCVAEKSTDDLLDIRRQWDRYINHDGHHQDIYQKVPPVFVTPSPPANAVWASYLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N1E3</accession>
    <name>A0A1C7N1E3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Inorganic pyrophosphatase</fullName>
            <ecNumber evidence="4">3.6.1.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Pyrophosphate phospho-hydrolase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="primary">ipp1</name>
        <name evidence="13" type="ORF">A0J61_09432</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>diphosphate + H2O = 2 phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:24576"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="EC" id="3.6.1.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the PPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.1.1" evidence="4"/>
    <dbReference type="EMBL" id="LUGH01000849">
        <property type="protein sequence ID" value="OBZ82516.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N1E3"/>
    <dbReference type="STRING" id="101091.A0A1C7N1E3"/>
    <dbReference type="InParanoid" id="A0A1C7N1E3"/>
    <dbReference type="OrthoDB" id="1608002at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004427">
        <property type="term" value="F:inorganic diphosphate phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006796">
        <property type="term" value="P:phosphate-containing compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00412">
        <property type="entry name" value="pyrophosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.80.10:FF:000004">
        <property type="entry name" value="Inorganic pyrophosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.80.10">
        <property type="entry name" value="Inorganic pyrophosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008162">
        <property type="entry name" value="Pyrophosphatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036649">
        <property type="entry name" value="Pyrophosphatase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10286">
        <property type="entry name" value="INORGANIC PYROPHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00719">
        <property type="entry name" value="Pyrophosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50324">
        <property type="entry name" value="Inorganic pyrophosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00387">
        <property type="entry name" value="PPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="12" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="12">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008889415" description="Inorganic pyrophosphatase" evidence="12">
        <location>
            <begin position="18"/>
            <end position="311"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006220"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00032535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00040300"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00047820"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="OBZ82516.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="311" mass="35075" checksum="1D025370D1A2D343" modified="2016-11-30" version="1">MLLSYLFLSNAVLAASGLSKPHEVTTRIIGAPHTSNYTVYFEQNNHAISAFHDIPLFANKEKTVYNMIVEIPRWTNAKNEINKETPLNPIKQDVRNQQPRFVPNIFPLKGYIWNYGAFPQTWENPKFVSPYTGKGGDNDPIDVIELGQEIASVGQIKQVKIIGIIGLIDQEETDWKVAVIDVNDPLANQLNDIQDVQQLLPGYMEESCRFFKYYKTPTGGNRNEIAFDGVPQNKTFATNIVLETHEQWKLLVNGVEPKKEIQTINLSVKNSPYRVSSDSDIVTSIPKANPLPAVKIAPIVDKWYFLSDSKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N1F6</accession>
    <name>A0A1C7N1F6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Arrestin C-terminal-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_09033</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000758">
        <property type="protein sequence ID" value="OBZ82920.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N1F6"/>
    <dbReference type="STRING" id="101091.A0A1C7N1F6"/>
    <dbReference type="InParanoid" id="A0A1C7N1F6"/>
    <dbReference type="OrthoDB" id="2333384at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.640">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014752">
        <property type="entry name" value="Arrestin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011022">
        <property type="entry name" value="Arrestin_C-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02752">
        <property type="entry name" value="Arrestin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Arrestin C-terminal-like" evidence="2">
        <location>
            <begin position="164"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="494"/>
            <end position="660"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="833"/>
            <end position="869"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="552"/>
            <end position="566"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="583"/>
            <end position="596"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="613"/>
            <end position="637"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="843"/>
            <end position="853"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02752"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ82920.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="881" mass="97714" checksum="2B29AF021BFCEF3F" modified="2016-11-30" version="1">MKDGFKSIEIEPVECYLDFVGPAKINDTNSRVLKGQIRISLTKPVKIRNMSIKFKGQSSVSLQLPTPVELTTPLLPKLKLPLYGRVTIPVGDHIIPWEMDIPNIYPRSIMIKRATITYKVILTISMGITRTLTAEYPIVIRRHLLPYKELAPIIETRLFQRTIPGKFHYEIDTPQIVCIEQEHIPLAIKYISFANQKEVKTIRTRLIQIELYRRQALSKAESDLSCNNKDSLILDLDRKLLDSADYKDTHIKYIKRTVPALIHIPNESASAWKSPCLIRHRLHPYMSFSLDSPMLSIYHQLEVTFQFGMKHEEVKSRIPIIIASIPKRDSLQLGSNVTPSAQSENMMLKYAFEEATHTNFLTYRLESHTSTLLTEDENEQLLIDGSYTTLRNGRTLPLMSVEDDIHSTSRYGRVSNALNSSSSEINDPRPGLVPYNSYASEQPPMNGITTLERNAIIKRSMANTTSITAAAAAVKAAQNAATQNQIDPQRFASAVELSSRSKDSSTPIDYSDSKRPRTTTPTARRQPMYKKHVPQPIDVDLANGKDIRNVSPFPPPRTQLPLPPPHRSTSSGSEVLPATDRAQQIQSLSQSLVQPSRRNLRQDSMDDLQSVYSEASASSSNNAPSLSSSATLSTNRSQPTLHSRPASPVFSPAPGLPATFALRPQQDSTAQIEETFLIDSAGATSPAMNTVASSTVFSPHSTSVFGRRIALSTISSLTNNSLYIDPSVVSRDRQSATLESDILSVIMRSSTENSCVGHEPSSYRHACHAPPCPSPNHYINAKLPPIPTTTSNQSSHSKRSNRFTMIYHGESEDEDDDCPTADPVMSQFGERTTSLPIDQLVPSSQSPSITSSSGTCPRSEGAPPRLPRLSFGNDFDFSINI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N1I1</accession>
    <name>A0A1C7N1I1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Myb-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_08952</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000742">
        <property type="protein sequence ID" value="OBZ82995.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N1I1"/>
    <dbReference type="STRING" id="101091.A0A1C7N1I1"/>
    <dbReference type="InParanoid" id="A0A1C7N1I1"/>
    <dbReference type="OrthoDB" id="2230048at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="62"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="109"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="62"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="139"/>
            <end position="155"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ82995.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="227" mass="25879" checksum="A5E201595B034D54" modified="2016-11-30" version="1">MSLKNISDEDCWFVIGAHQAGASERQCAELSGLSRGAIHNILLNFRKLGSPHANQLSLDNLIDPHKQKQQSHTKDKSFPRKRGRPPKPKEAPFFTEAIVQETLAQARGSQIMNQRVHKKPRIYPAERLDTPPASDEDSQSLSSPERNILPTTPRSTTDESEDELKQAEDWTVEDDKALLMHVLNLPSKHVKWKEAELLFNNRHLSIICADRWEFIKQHLLKDVQQAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N1P4</accession>
    <name>A0A1C7N1P4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Alternative oxidase</fullName>
            <ecNumber evidence="13">1.-.-.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">AOX</name>
        <name evidence="14" type="ORF">A0J61_10657</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="12 13">
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </cofactor>
        <text evidence="12 13">Binds 2 iron ions per subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 13">Belongs to the alternative oxidase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.-.-.-" evidence="13"/>
    <dbReference type="EMBL" id="LUGH01001294">
        <property type="protein sequence ID" value="OBZ81294.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N1P4"/>
    <dbReference type="STRING" id="101091.A0A1C7N1P4"/>
    <dbReference type="InParanoid" id="A0A1C7N1P4"/>
    <dbReference type="OrthoDB" id="16906at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098803">
        <property type="term" value="C:respiratory chain complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009916">
        <property type="term" value="F:alternative oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010230">
        <property type="term" value="P:alternative respiration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01053">
        <property type="entry name" value="AOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1260.140">
        <property type="entry name" value="Alternative oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002680">
        <property type="entry name" value="AOX"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038659">
        <property type="entry name" value="AOX_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31803">
        <property type="entry name" value="ALTERNATIVE OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31803:SF3">
        <property type="entry name" value="ALTERNATIVE OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01786">
        <property type="entry name" value="AOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005229">
        <property type="entry name" value="AOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 13" id="KW-0249">Electron transport</keyword>
    <keyword evidence="10 12 13" id="KW-0408">Iron</keyword>
    <keyword evidence="11 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="6 12 13" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9 13" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 13" id="KW-0679">Respiratory chain</keyword>
    <keyword evidence="5 13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="binding site" evidence="12">
        <location>
            <position position="137"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="176"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="176"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="179"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="227"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="278"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="278"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="281"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <label>2</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008388"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022660"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR005229-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU003779"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="OBZ81294.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="317" mass="36012" checksum="DF95E70B550AC513" modified="2016-11-30" version="1">MLTMITVAPTQSKILLKAAIPVLSRMAAPTTLALSRRAFSNSTQKSQDAALSDIASRMPRDIYREVLESKPVPMREEFLKTNKLTPELLEKIEFSPGKHFVPQTMGDRMALYTVKFLRTLPDTYFGKDHYMRAVMLETIAAVPGMVGAMLRHMKSLRSMKEDNGWISHLLHEAENERMHLMTWIKCLEPSLWNRLLVLGAQGVFFNAYFLLYLASPKVAHRMCGYLEEEAVISYTHFLEDIDSGILKNGPAPQVAIEYYNLHPNATIRDVVLAVRADEAVHRDANHFFSDRIAQQKEDILSEVKARYEQEASHGSMA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N205</accession>
    <name>A0A1C7N205_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative methyltransferase C1B3.06c</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_09289</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000817">
        <property type="protein sequence ID" value="OBZ82659.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N205"/>
    <dbReference type="FunCoup" id="A0A1C7N205">
        <property type="interactions" value="432"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N205"/>
    <dbReference type="InParanoid" id="A0A1C7N205"/>
    <dbReference type="OrthoDB" id="2013972at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041698">
        <property type="entry name" value="Methyltransf_25"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43591:SF24">
        <property type="entry name" value="2-METHOXY-6-POLYPRENYL-1,4-BENZOQUINOL METHYLASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43591">
        <property type="entry name" value="METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13649">
        <property type="entry name" value="Methyltransf_25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransferase" evidence="2">
        <location>
            <begin position="216"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="46"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="58"/>
            <end position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ82659.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="450" mass="51632" checksum="3A10849529B75E98" modified="2016-11-30" version="1">MGNQASRIDRESSTIASDDPCLNNIRQWHINDTDEPYRRQYPLPAITNDHNRIKPRKQSSPAAVTHPSNNNSSTITLTCPNTTLDVINEPQQQPNLIHPLAPTVASPKEFFSFDHRTNNAIGTIPEHNQRITNNRNSLSSSQLKQATEHHLEQEQLFSCRTLGERKYAHIKGSNYLLPCDEEEVDRLHLQHFMIRFAIQGNYLAPVSEVLRKGGRVLDVGCGPGAWSMEIAGEYPKSTVIGIDIAPIYPKDIIPSNCVFYQCNVLNKLPFEDNTFDYIFMRFRSLFYKHRFMGQGVESNKWSTVLAELVRVLKPKGWIEWIETDSEIHRPGPVTHDFNRKLMELMTKNKQDPHIGRTLKERLSQNSDLINITSTYVSCPGGQWAGKLGQLTMQSWKAYYQAFSPLICQLCEMGAKEYTDKLKSCWREADEYKTFENVHFSYAQKRVVVLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N219</accession>
    <name>A0A1C7N219_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_09273</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000813">
        <property type="protein sequence ID" value="OBZ82679.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N219"/>
    <dbReference type="InParanoid" id="A0A1C7N219"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="33"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="40"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="75"/>
            <end position="86"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ82679.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="86" mass="9983" checksum="0D530C7C10D7C892" modified="2016-11-30" version="1">MFLAILYCLKRVGHTRSRQQTAQPHYVVVDMNGHTTHQPIHPPTYEPPPTQYRTSDPIVTYRPPDDSLEPPPPSYKDHRKDRVPIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N2Q7</accession>
    <name>A0A1C7N2Q7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Ricin B lectin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_08549</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000669">
        <property type="protein sequence ID" value="OBZ83403.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N2Q7"/>
    <dbReference type="STRING" id="101091.A0A1C7N2Q7"/>
    <dbReference type="InParanoid" id="A0A1C7N2Q7"/>
    <dbReference type="OrthoDB" id="2218237at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008889447" description="Ricin B lectin domain-containing protein" evidence="1">
        <location>
            <begin position="22"/>
            <end position="186"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ83403.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="186" mass="21203" checksum="83A4980089C8D3A9" modified="2016-11-30" version="1">MLFSQLTVFLAAFISICSASARFQIRSPRTSGLLGFKYDKKPFFGGKCSETYDKYLKVQSSGEGVHFKLTGCTDEGYCHLKITDGDYKGYCLGGQERPESQSCTGYENNIYKLNMDFTISTVGGLYLGLGNEYADDCDKFHYVKLSKEKFHWVIEKDKDFADYDDYYYDYYHPRGGAQRVIGGCHH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N3P7</accession>
    <name>A0A1C7N3P7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_08206</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000611">
        <property type="protein sequence ID" value="OBZ83743.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N3P7"/>
    <dbReference type="InParanoid" id="A0A1C7N3P7"/>
    <dbReference type="OrthoDB" id="2448307at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040410">
        <property type="entry name" value="UPF0658_Golgi"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34391">
        <property type="entry name" value="UPF0658 GOLGI APPARATUS MEMBRANE PROTEIN C1952.10C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34391:SF1">
        <property type="entry name" value="UPF0658 GOLGI APPARATUS MEMBRANE PROTEIN C1952.10C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="58"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="92"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="130"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="189"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="223"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="252"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="290"/>
            <end position="311"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ83743.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="345" mass="39499" checksum="322F8F4B7867D4DC" modified="2016-11-30" version="1">MFEPVRDARTEKRFNFWSSSPNSVFLVILCIFEAIVVIALEAVIYAKFSVTEFSEDNLGLGIPVYLMIFIFSQVFQVLIAWDAVRAQNTIQIIAFLLFNICCFAYAVFQFKQIGDAIDPNTVSTEQLAASLSYLISRLLIVIAVIIGVCQVVYCYIGARLYQEFGWKIYKKIGADPEIRKLKRESLDMYRWFQIILTILKIDFFFFLGYSIQYLVLVLHHDDYEYPLTIVAIPLTCLFLLLAVYAIRHESKWLMGLFFVGTCAATAYFIFKICRIYDPQEAHKYTFVKAFLTFFASVSLALLVLTIINAAICCSNFGKGLKPHLLSSNRHSSLPQDATERTFSLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N3Y1</accession>
    <name>A0A1C7N3Y1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Serine/threonine-protein kinase HT1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">HT1</name>
        <name evidence="3" type="ORF">A0J61_08230</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000615">
        <property type="protein sequence ID" value="OBZ83718.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N3Y1"/>
    <dbReference type="STRING" id="101091.A0A1C7N3Y1"/>
    <dbReference type="InParanoid" id="A0A1C7N3Y1"/>
    <dbReference type="OrthoDB" id="6718656at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00180">
        <property type="entry name" value="PKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051681">
        <property type="entry name" value="Ser/Thr_Kinases-Pseudokinases"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44329">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE TNNI3K-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="2">
        <location>
            <begin position="134"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="167"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ83718.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="483" mass="54660" checksum="1841181D66D7A222" modified="2016-11-30" version="1">MNRNEAETVCPQQLLERLLDSTRLKVKLFIESCPAAFGLENLITQTKVLPSINKRILQLYQEVCETYINQGVPFDHSWNWTIVWRQQLSLKCLADCYGQERVMAAAHPRARKAIHQIYLENLDAYMQWFPWSWFSEMQFIGAGGFSAVYSVNTMPAYDPQPQKMALKIVDDKLLNEISVQSKAFLPLLFQGLTVCESTGDLMMVMKCSNDGNLEDHMQQLPLGDLDLKTITGTILRLAANLADLHRVGMCHRNVHPRNIVCTDSDYFLVDYRFATPSHESSSVTAITKAVYGRLPYIAPEVRQGVYTEKSDIYSLGVIIWQLVSKVIFPSPDVLLDGAQLSPEDHVYRIEPLPGLPEWCQNLYKACLNPVPDNRPDASEICQVLQPIHDALDYSVPLDRRVTGYIVARRAEAADHLRTYTKVKGLVSSSMTRLYTLSNLPSTQSLVLLPFENAPFQNIWSMDDTCSDTFSLSTYIDTSAPSFI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N4A6</accession>
    <name>A0A1C7N4A6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_08059</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000588">
        <property type="protein sequence ID" value="OBZ83891.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N4A6"/>
    <dbReference type="InParanoid" id="A0A1C7N4A6"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="21"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="21"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ83891.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="501" mass="58194" checksum="03E799492F237DC0" modified="2016-11-30" version="1">MKGVRALVPMGCINFDENAPSSVQDQQKVNQASNSMPDSPMKEVTLQSVTVSHEVLAYYGEPNPLELVDDILDFYEDDEMYLDVKRQYILSADDEFISVSNTQNSEIHQIFRDGNVSHAVIDEIFKRYNKNHRDLPPLNSFNRERTQNKQESVFRPREVDQCSVCHCAFNKFNETHYPSCGGSRSDKHGDSVLKHLQLEVALQLASLFKNETFAKQSKFFGMDCLKNDLQRRLLGQANKKNIVVRGRATQRDIDDDEIEELDTLVQKWVGFLHDNMPPTASNVNMHYLTHLTQWLKAYHLYRTNCKPLERRIQRMKRMIKSTSSTIRNAENVMIDEAYRNFQIRSTINYNKPIEAEKDMRPQFTLKKCLDNFRSIDLSGHLSKHKHVTRKFDSSRLSCYALVQREGETEPAIAEILLLFRNEDINYALVHFYQGVKVSDAVSLEALLVPIAMLQSDTNLDKYFGRMYFFWSNMSRTAVPIEDYHFFFDFEDDNYSASDDDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N4L2</accession>
    <name>A0A1C7N4L2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">26S proteasome non-ATPase regulatory subunit 10</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">Psmd10</name>
        <name evidence="4" type="ORF">A0J61_07915</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000566">
        <property type="protein sequence ID" value="OBZ84033.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N4L2"/>
    <dbReference type="STRING" id="101091.A0A1C7N4L2"/>
    <dbReference type="InParanoid" id="A0A1C7N4L2"/>
    <dbReference type="OrthoDB" id="539213at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000502">
        <property type="term" value="C:proteasome complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:1904855">
        <property type="term" value="F:proteasome regulatory particle binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044183">
        <property type="term" value="F:protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070682">
        <property type="term" value="P:proteasome regulatory particle assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24173">
        <property type="entry name" value="ANKYRIN REPEAT CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24173:SF74">
        <property type="entry name" value="ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13637">
        <property type="entry name" value="Ank_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13857">
        <property type="entry name" value="Ank_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01415">
        <property type="entry name" value="ANKYRIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="4" id="KW-0647">Proteasome</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="33"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="67"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="100"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="133"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="166"/>
            <end position="198"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OBZ84033.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="221" mass="24234" checksum="D9F20A014163528C" modified="2016-11-30" version="1">MLTIFQAAYEGKLFVVQQMTEADANLVNSFDEDGRNALHWAASGGHRDIVDYLLNKGASVNTQDKEAAWTPLIIAVSAGHTDVVKLLLEKGADASLENETQQSALHYAASKNRVEICRLLLEHQAPVNQINKYKQTPLHRAAMGGYIKVIELLLAYKSRVNPKDAEGNTPLHLACEEGHGDCAVYLIEHNGNLDNLNNQSQSPIDLCPTKEVKSFILSATS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N594</accession>
    <name>A0A1C7N594_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_08114</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000596">
        <property type="protein sequence ID" value="OBZ83836.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N594"/>
    <dbReference type="STRING" id="101091.A0A1C7N594"/>
    <dbReference type="InParanoid" id="A0A1C7N594"/>
    <dbReference type="OrthoDB" id="2019644at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005643">
        <property type="term" value="C:nuclear pore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021827">
        <property type="entry name" value="Nup186/Nup192/Nup205"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11894">
        <property type="entry name" value="Nup192"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81995">
        <property type="entry name" value="beta-sandwich domain of Sec23/24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="188"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="191"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="368"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ83836.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="368" mass="41812" checksum="99DFFD9C55CCBF56" modified="2016-11-30" version="1" fragment="single">MTTLREELCTLLGRVCNRPKLSSQASATLAKETLSSMKEVFIKPFNESPKDSKFRTSLQSDKTFTIDNKEFRANDDFVKHAIFLSDQLDISEKEACRLLHGGNSIAALINSTSLNATVSLYHDERGYTLAILNNVLQYVKEQPSNSFSRLLFIQFIKELMTTDQSFIKNILTSEKKIAKLISTLTNEKDSASTSNTMTATANNSQAQQQQQQQQQQQQQQPSSLFQPQQQQQSSLFQPQQQQSSLFQSQQPQQLQQPPVDGLKFDKETNTFRIERLVEERAYMVQILYHLASLFWLSEADLLTVLEHVQTKNLSDASHPYLMVAVLAALSSRNKENPENQISNNDASIKKIHEQITSKQWKISTSKAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N5W9</accession>
    <name>A0A1C7N5W9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 8">Leucine carboxyl methyltransferase 1</fullName>
            <ecNumber evidence="3 8">2.1.1.233</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">LCMT1</name>
        <name evidence="10" type="ORF">A0J61_07459</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Methylates the carboxyl group of the C-terminal leucine residue of protein phosphatase 2A catalytic subunits to form alpha-leucine ester residues.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>[phosphatase 2A protein]-C-terminal L-leucine + S-adenosyl-L-methionine = [phosphatase 2A protein]-C-terminal L-leucine methyl ester + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:48544"/>
            <dbReference type="Rhea" id="RHEA-COMP:12134"/>
            <dbReference type="Rhea" id="RHEA-COMP:12135"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:90516"/>
            <dbReference type="ChEBI" id="CHEBI:90517"/>
            <dbReference type="EC" id="2.1.1.233"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the methyltransferase superfamily. LCMT family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.233" evidence="3 8"/>
    <dbReference type="EMBL" id="LUGH01000503">
        <property type="protein sequence ID" value="OBZ84490.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N5W9"/>
    <dbReference type="FunCoup" id="A0A1C7N5W9">
        <property type="interactions" value="366"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N5W9"/>
    <dbReference type="InParanoid" id="A0A1C7N5W9"/>
    <dbReference type="OrthoDB" id="203237at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018423">
        <property type="term" value="F:protein C-terminal leucine carboxyl O-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009966">
        <property type="term" value="P:regulation of signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.150:FF:000092">
        <property type="entry name" value="Leucine carboxyl methyltransferase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016651">
        <property type="entry name" value="LCMT1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007213">
        <property type="entry name" value="Ppm1/Ppm2/Tcmp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13600">
        <property type="entry name" value="LEUCINE CARBOXYL METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13600:SF21">
        <property type="entry name" value="LEUCINE CARBOXYL METHYLTRANSFERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04072">
        <property type="entry name" value="LCM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016305">
        <property type="entry name" value="LCM_mtfrase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8 10" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 8 9" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="6 8 10" id="KW-0808">Transferase</keyword>
    <feature type="binding site" evidence="9">
        <location>
            <position position="54"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="80"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="159"/>
            <end position="160"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="186"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000724"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012834"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00017497"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRNR" id="PIRNR016305"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR016305-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OBZ84490.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="328" mass="37464" checksum="AE64CA6926C8885A" modified="2016-11-30" version="1">MQTNDDVVRGTNDDATISRMSAVSLNYIQDPFVHLFVKKPVRRSPIINRGTFIRCLALDSIISQFLSLAGPIKKQIVALGAGFDTRYFNIKAGHLCHHGKSLSHHLSRYFEVDFPEITMKKAMAIKRRKELSALLEGSVSLERGGMDLKSDQYCLIGGDLREWPEVSQRLIASGLDTELPTLFLSECVFIYLPPEDSNCILQWITKTMRNAMFGLYEQIKPNDAFGQMMIRNLKSRDIDLKGIHAFPDLVHQENRFKELGWQSAKAVDINKIHDSYLDPSEIARIAKLEMLDELEEWRLLSAHYCIAWAAHSVDYLKEFESVNLESKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N633</accession>
    <name>A0A1C7N633_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Mitochondrial zinc maintenance protein 1, mitochondrial</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">MZM1</name>
        <name evidence="10" type="ORF">A0J61_07338</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Assembly factor required for Rieske Fe-S protein RIP1 incorporation into the cytochrome b-c1 (CIII) complex. Functions as a chaperone, binding to this subunit within the mitochondrial matrix and stabilizing it prior to its translocation and insertion into the late CIII dimeric intermediate within the mitochondrial inner membrane. Modulates the mitochondrial matrix zinc pool.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Interacts with RIP1.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion matrix</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the complex I LYR family. MZM1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000489">
        <property type="protein sequence ID" value="OBZ84615.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N633"/>
    <dbReference type="FunCoup" id="A0A1C7N633">
        <property type="interactions" value="94"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N633"/>
    <dbReference type="InParanoid" id="A0A1C7N633"/>
    <dbReference type="OrthoDB" id="529194at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044183">
        <property type="term" value="F:protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034551">
        <property type="term" value="P:mitochondrial respiratory chain complex III assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd20267">
        <property type="entry name" value="Complex1_LYR_LYRM7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045298">
        <property type="entry name" value="Complex1_LYR_LYRM7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050435">
        <property type="entry name" value="MZM1/LYRM7"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46749">
        <property type="entry name" value="COMPLEX III ASSEMBLY FACTOR LYRM7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46749:SF1">
        <property type="entry name" value="COMPLEX III ASSEMBLY FACTOR LYRM7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0143">Chaperone</keyword>
    <keyword evidence="6" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0809">Transit peptide</keyword>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="95"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="9">
        <location>
            <begin position="106"/>
            <end position="117"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004305"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009949"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011589"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00015108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00025268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OBZ84615.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="127" mass="14298" checksum="583BB035E6C064FB" modified="2016-11-30" version="1">MSISPSKQAAIQAYRHLLKTQREVFGADHRAILAAKRETYARFMQSKDETNTTVLEEKLELAGQVASLLRRNVIQAVPKGDDTYKLRITKDTELGDNDSIKNTKNINRKNRKGKKHEHTGGCCGGHH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N660</accession>
    <name>A0A1C7N660_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Sporulation-specific protein 5</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">spo5_1</name>
        <name evidence="6" type="ORF">A0J61_07426</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000500">
        <property type="protein sequence ID" value="OBZ84527.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N660"/>
    <dbReference type="InParanoid" id="A0A1C7N660"/>
    <dbReference type="OrthoDB" id="271725at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002343">
        <property type="entry name" value="Hud_Sxl_RNA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24012">
        <property type="entry name" value="RNA BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00961">
        <property type="entry name" value="HUDSXLRNA"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 3" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="5">
        <location>
            <begin position="216"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="5">
        <location>
            <begin position="307"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="95"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="430"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="99"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="431"/>
            <end position="461"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OBZ84527.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="494" mass="54085" checksum="E088A42C6929707E" modified="2016-11-30" version="1">MTERKERANGNRRNPQPPPQQVFMAPSSPTYPPYATFVDVPTQVIYDPNDPNHTTTTATTTTYAYVYPVSPQFSVQYYPSAQAAAAAAAAASGGQVHATPSNTSSNTTSSPPPIDNVRYGSYPGSPILHPHLHYSSPQMHPSSPPFSPTLQYHSPPTHAFVLPPHQQHFPPLHISSPVLTASGSPQHQFVQPLSFDLKKRQEQMDEYAHLHQFHPQNIYVRGLPATETDESFLELCQVYGPISSSKAILDQKTGECKGYGFAMYENQEHCQLAINGLNAAGYQASLARVGQESFSSKLKSLQDETSTNIYISNLPLSMDEDALEELFKPYQTVSNRILRDPQSGLSRGVGFARLVDRLSASAIIDKFNGHSISGSSAPLQVRFADSPAQKRLKNQTSTSKRTIKTLRDNIFPFPIRPMMPITPETMLGIAPSSSTSSSLNGYPRSLQTEPIPQPITDNTNNTKTSMCDDIDSITHTVNQIDLKDKEATGGGLVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N690</accession>
    <name>A0A1C7N690_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">A0J61_07413</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the non-repetitive/WGA-negative nucleoporin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000499">
        <property type="protein sequence ID" value="OBZ84541.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N690"/>
    <dbReference type="STRING" id="101091.A0A1C7N690"/>
    <dbReference type="InParanoid" id="A0A1C7N690"/>
    <dbReference type="OrthoDB" id="338970at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044611">
        <property type="term" value="C:nuclear pore inner ring"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017056">
        <property type="term" value="F:structural constituent of nuclear pore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006606">
        <property type="term" value="P:protein import into nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036228">
        <property type="term" value="P:protein localization to nuclear inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006405">
        <property type="term" value="P:RNA export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000972">
        <property type="term" value="P:transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.1780">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.440">
        <property type="entry name" value="Nucleoporin, helical domain, central subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.450">
        <property type="entry name" value="Nucleoporin, helical domain, N-terminal subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007187">
        <property type="entry name" value="Nucleoporin_Nup133/Nup155_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014908">
        <property type="entry name" value="Nucleoporin_Nup133/Nup155_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004870">
        <property type="entry name" value="Nucleoporin_Nup155"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042533">
        <property type="entry name" value="Nucleoporin_Nup155_C_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042537">
        <property type="entry name" value="Nucleoporin_Nup155_C_2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10350">
        <property type="entry name" value="NUCLEAR PORE COMPLEX PROTEIN NUP155"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10350:SF6">
        <property type="entry name" value="NUCLEAR PORE COMPLEX PROTEIN NUP155"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03177">
        <property type="entry name" value="Nucleoporin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08801">
        <property type="entry name" value="Nucleoporin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Nucleoporin Nup133/Nup155-like N-terminal" evidence="6">
        <location>
            <begin position="60"/>
            <end position="518"/>
        </location>
    </feature>
    <feature type="domain" description="Nucleoporin Nup133/Nup155-like C-terminal" evidence="5">
        <location>
            <begin position="673"/>
            <end position="1076"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007373"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF03177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF08801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OBZ84541.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="1092" mass="124472" checksum="18E52E1E76AE2DB3" modified="2016-11-30" version="1">MNNTVSQQPKEQIPSRYVEFMKTGREIEQVISKDSNYPDLADMLKAATSSTYALPLINSEREFSEIGKTNTPAHLYDRIANVQCRTFSGIFPQISRAWLTIDNILYLWDYTEPDASIFEYKDQDQVITTAEIMKPKKGILDDSVEYVIAVATPLQIIFIAASNTAHANNHAPQHDANKAEGYQYFATRATISTDEVRCRKMFSTEDGRLFLISNDGSLHEIFLASSADSWFGRDHMVRRTYSTAPSLFQRLLNTVQHRPSRVNITNLSAYPLAFIQSAVVDNERNILYLLCERSMIEVVYLGDPAQPYKPVFMYQSITEDGTQLARQSGKTSAASDFEVSSIHVISTQESKRYHLVAVTKTGHRLYFSHHQDGIRSTMATTGPPNALVLGHLRFPPVEPIHPGEIAPVYSKSFYDRGLCISVRARDDLSDSLQIASVGTGKLISPKALQTNPSTNYTNINNNNTSLSDSYYETRASLQIPEKVSTLVELKPKNLTRLALNEVSEQLSDTPRQFAVLTTQHIRFYQKQRPVDILHYLIQQYNKQPNLYRHHIETFSEKYSQREACAMCLSIACHSVDTRVIETAVKLFERFGGQPSSTSSPRVMGNFLTLVAKGDSVVFSGKRDGLLLYFARIISPVWKLKFFTARYPQLHTSPDIADPKFELNDDSSISSEVADRQSMHTIYITLVKAIEAISFIAFAVDAIMYTGIKQFLSDNVDKDKVYVLDLCSILTTVDGREFVDEIVIGIIVRFRSGYGHVGHHFVSEELQTKCSHFFGPDSIAFYKGLEHLLSVDYEDSEAEKDRDLRQSLAYFKQAADSLTKLASICTQYKRHSFHMGIIELALERAHRLDPTEKAFLAYEDPELQTESNMALIFDRFHVYTYILDALADAAAAKSNPASPEYSRIENPSQFYQNLLNRALASSDRCFHYRLYQWLIENNLMSDLLSVNSPLLLRYLERYESDKKMKYEFLYQYYRTREDYIQASRYMTALAHIDNISLQSRSEYFANALITAQCIAIQAPEYDHNYVNQLRQRLAWVQLQKRVQDIIRIQGGLDSANAIEQLNRSLFSPEQLRTDFAQFPHVVQLLNEEAVHSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N6X0</accession>
    <name>A0A1C7N6X0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Protein MON2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">mon2</name>
        <name evidence="7" type="ORF">A0J61_08877</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000727">
        <property type="protein sequence ID" value="OBZ83074.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="FunCoup" id="A0A1C7N6X0">
        <property type="interactions" value="593"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N6X0"/>
    <dbReference type="InParanoid" id="A0A1C7N6X0"/>
    <dbReference type="OrthoDB" id="294853at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032629">
        <property type="entry name" value="DCB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032691">
        <property type="entry name" value="Mon2/Sec7/BIG1-like_HUS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032817">
        <property type="entry name" value="Mon2_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34199:SF4">
        <property type="entry name" value="ARM REPEAT SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34199">
        <property type="entry name" value="NUMOD3 MOTIF FAMILY PROTEIN, EXPRESSED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16213">
        <property type="entry name" value="DCB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16206">
        <property type="entry name" value="Mon2_C"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12783">
        <property type="entry name" value="Sec7-like_HUS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0653">Protein transport</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Mon2/Sec7/BIG1-like dimerisation and cyclophilin-binding" evidence="6">
        <location>
            <begin position="3"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="domain" description="Mon2/Sec7/BIG1-like HUS" evidence="4">
        <location>
            <begin position="234"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="domain" description="Mon2 C-terminal" evidence="5">
        <location>
            <begin position="1020"/>
            <end position="1278"/>
        </location>
    </feature>
    <feature type="domain" description="Mon2 C-terminal" evidence="5">
        <location>
            <begin position="1284"/>
            <end position="1806"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="954"/>
            <end position="983"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="960"/>
            <end position="969"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="970"/>
            <end position="982"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF12783"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF16206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF16213"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OBZ83074.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="1817" mass="203450" checksum="29A6B9800C78B1D7" modified="2016-11-30" version="1">MSGLTAFLQTELLTLSSEARRKHPEIKEVYVDLSPYSLKLTCAAERLSVILRSFKERPGYSIANELAKTEDALRPFVLACETKQVKLVTIAIGCIQKLISFHAIPEVRIHCLENYTRTSIRAVLRTLTDISVHGMDIQLKILQTVLPLLSNYRSVHDDILAELKFLCEQALLICFRLQDSKIAVVNNTAAATLRQLVIFVFDKVGKENASKPSEAETTHEVEISTGEKIQLRPCAKDAYYLFQDLCLLTNGDQPEYLRLTHLSKTFGLELIESILTNHYRLFREHKELNAILKERVCPMFIKSFSEKSEFPHTMRLTRVVYILVKQFSELLVMECEIFLSMFVKILEPENPIWHRVLAMEIFKGICSDAALTSSIYRWYDGQSSSTNVFRDMITAFGRLATEKPQSIGASQGGRDSLDYGSQNTGIYSSHTNQHTSLVLESLSTSSSTMRIQWYCIIIFPTGHDKSDPPTIPDTYIYYLALVCLNSIADGLAGYTLPEFSPGFTKSASTNESGTDQKKDLTIVTEMANVAWPGLLAAMSFYLTANLDEELFQSTMRSYQNFTNVCGVLDLITPRDAFLTNLCKNSIPNIPLLSSGLTSTSATKSTISSTSVATLSSISTSNAISFTDLSVQQQQALVNITLNEKNLYSLRVLLNIAMFLSSVLGSSWYLVLETXQLADFLLFNRPVPKGSSNTPVSGSTNNLRRTMTNSSVASANQSPGLTSPPLNQMMDADHLPIISASFQRLFENSRYLDDKSFVAFSSALCRLSSEVSGAPFSDSQSLSASKSSRIIQIDAYPFVCLEYIATLDMGRLIDTQKESSSEAWHLITSHLIATANYPLTPSSVRTQCCVTISNIITTAMEFVLSEFNQVNEDTQKRLLVVLNQCINYTTPTKDEALVQEAISNNPKIFSEVQKMGLXTLNNLLQTAGHSLTCGWKLIFDMLRHVAVCAIGPPPDTSFDSNSDEEEEEEKENSNSENKNERASVDTTASSVFAGSIMAAAGPKSVTGLIKVAFASLQLICTDFLSLLSPDCLRLCIATLGSFGMQSDDLNISLTAVGLLWNLSDFIQTRRIDLIKKRDSAFVDEKIDKEHMNIDVKLEDEDDGNPKTYSVLWMLLLLQLSHTCIDWRPEVRNGANQTLFRTITMNGHVLGPQLWDTCIWEVLFPLLDSIKMSSIRASKISLSKASSPNAHNDRDSSGFMLHHSRDTADKQWDETKVLILTGISSIFQDFSNDLHELEHFQRAFTLLLAHLEDSCLRSSQEVSFASIKSFKTIVTVSPENKDPSKMMNLWRKAWNTWEVIGYSISQSMDDQPLPDKSEKKHKSYDDEAELQSLTLSLSSSSVAPISKDFTQDTLTSYVSMFVDLYKHIYSTFTLDDVSSLLSILRNLLVYSTSPQYRPDVDHVSPLQEAVLEAVQTLDMKKEGVPPLVLADLAEYMTLAFLSPPEDKQNKNRGYIPPSQRKFSTVTYIALNKKCSSLVADLFKDHVHVLSLYTEGVFERIIGAYGLPMKLKYDCPPSYKHGDDKTPLWKLATSGLLEILKLGLESLEDFGEEVSEERFCGVWRTLIDILEGSLLSPSSPPENMKIEELDVDEHFDISVLSAIQNDVVVHMGQPRVPSEVIEKLINVIRESSRLYYIEESISKEGDINEKGPSILSVDRSSDIAGTTGTIVPVMRESFAYASLMTLFNLCSARDNDNIPQVRKRVARVAINVLLERCETILRNYTADEPLLGRCPFPRVRKEEIVFLLKQSIQLKLQDDILTPNNDDHNEVKRLLLYGPRAHLFYLYPSLYNMITCKDDTVVSFVKECLHIMGSEMGLIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N7E0</accession>
    <name>A0A1C7N7E0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Lipopolysaccharide-induced tumor necrosis factor-alpha factor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">LITAF_1</name>
        <name evidence="8" type="ORF">A0J61_06975</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the CDIP1/LITAF family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000447">
        <property type="protein sequence ID" value="OBZ84981.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N7E0"/>
    <dbReference type="STRING" id="101091.A0A1C7N7E0"/>
    <dbReference type="InParanoid" id="A0A1C7N7E0"/>
    <dbReference type="OrthoDB" id="5599753at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006629">
        <property type="entry name" value="LITAF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037519">
        <property type="entry name" value="LITAF_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23292:SF6">
        <property type="entry name" value="FI16602P1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23292">
        <property type="entry name" value="LIPOPOLYSACCHARIDE-INDUCED TUMOR NECROSIS FACTOR-ALPHA FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10601">
        <property type="entry name" value="zf-LITAF-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00714">
        <property type="entry name" value="LITAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51837">
        <property type="entry name" value="LITAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="178"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="domain" description="LITAF" evidence="7">
        <location>
            <begin position="140"/>
            <end position="222"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OBZ84981.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="223" mass="25811" checksum="EA505A50507E06B0" modified="2016-11-30" version="1">MSVLFSSNTSFNDHLKIGHPQALQKRSLLRKSREDRPHDIRLSADTQPIEQDSQSACSVYSFSQTTSPVVSSAHHHTLYYFNSPQQNDPTDYFSPQPIPRKASTPLSYLKRKRDALLRYSTHRLHSSNSSLKSTPSTHLPGRTIRMPNQHLPDFETQVFCPRCEKYVHTRLRYRNGAMVYLVAFVLLLCTVFLFWVPFYVKYFKDVSHYCPGCGKRVGISRRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N7F0</accession>
    <name>A0A1C7N7F0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="1">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">oca2_3</name>
        <name evidence="12" type="ORF">A0J61_07411</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="1"/>
    <dbReference type="EMBL" id="LUGH01000499">
        <property type="protein sequence ID" value="OBZ84539.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N7F0"/>
    <dbReference type="FunCoup" id="A0A1C7N7F0">
        <property type="interactions" value="77"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N7F0"/>
    <dbReference type="InParanoid" id="A0A1C7N7F0"/>
    <dbReference type="OrthoDB" id="6513151at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd13994">
        <property type="entry name" value="STKc_HAL4_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24343">
        <property type="entry name" value="SERINE/THREONINE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24343:SF137">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE HRK1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 12" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="11">
        <location>
            <begin position="204"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="47"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="97"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="118"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="233"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="OBZ84539.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="525" mass="59771" checksum="E7EEFD56811BF5BA" modified="2016-11-30" version="1">MSSHSVVIDTSHLDENQLAEKLNHIDFNAPAKIFQNKHAIHQFENVTPDVSMPGTPLLTPNRQPQIKYESDSSSGYPSPSLPPTAVHTPPSLSPQHSGDEASHPSKLLDSDSLDPKGLPSYASTSSLPSRPSTPSQFVFKKPQYNKEYHHTHFHRLEKKDTLFKDLKKIFRSDKKKEKHKTLHKSSSQISFANEFNKDLEGKYGKWGRFVGKGAGGSVRLIRRNTDGKTFAVKQFRKRAPNEPEKEYVKKVTAEFCIGSTLHHINVIETLDIIQEGHHFFEIMEFAPNDLFNIVMSGKMTREEIACCWRQLLNGVSYLQQMGLAHRDLKLDNMVLDERGIVKIIDFGCAVVNKYPHETRVHRSKGICGSDPYIAPEQFTEPDYDARLTDLWSCAIVFICMSIRRFPWRLPRPEKDQSYKNFITPSTMGADKLFKMLPRESRAIIKRILTPDPAKRCTLEDVLQDEWVQSIPMCTPTQPELGHPHHLTMEPRPEVKSCCHIVVLDIPPPLEDSDASTHVKKNKAKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N7G5</accession>
    <name>A0A1C7N7G5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Glycine--tRNA ligase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">glyQS</name>
        <name evidence="6" type="ORF">A0J61_07042</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000456">
        <property type="protein sequence ID" value="OBZ84908.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N7G5"/>
    <dbReference type="STRING" id="101091.A0A1C7N7G5"/>
    <dbReference type="InParanoid" id="A0A1C7N7G5"/>
    <dbReference type="OrthoDB" id="57698at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004820">
        <property type="term" value="F:glycine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006426">
        <property type="term" value="P:glycyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.800">
        <property type="entry name" value="Anticodon-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="entry name" value="Bira Bifunctional Protein, Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002314">
        <property type="entry name" value="aa-tRNA-synt_IIb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006195">
        <property type="entry name" value="aa-tRNA-synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004154">
        <property type="entry name" value="Anticodon-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036621">
        <property type="entry name" value="Anticodon-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027031">
        <property type="entry name" value="Gly-tRNA_synthase/POLG2"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003211">
        <property type="entry name" value="PRK04173.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10745:SF8">
        <property type="entry name" value="DNA POLYMERASE SUBUNIT GAMMA-2, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10745">
        <property type="entry name" value="GLYCYL-TRNA SYNTHETASE/DNA POLYMERASE SUBUNIT GAMMA-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03129">
        <property type="entry name" value="HGTP_anticodon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00587">
        <property type="entry name" value="tRNA-synt_2b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01043">
        <property type="entry name" value="TRNASYNTHGLY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52954">
        <property type="entry name" value="Class II aaRS ABD-related"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="Class II aaRS and biotin synthetases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50862">
        <property type="entry name" value="AA_TRNA_LIGASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 6" id="KW-0436">Ligase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aminoacyl-transfer RNA synthetases class-II family profile" evidence="5">
        <location>
            <begin position="245"/>
            <end position="438"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OBZ84908.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="552" mass="64345" checksum="F7C353B92E06D880" modified="2016-11-30" version="1">MAQQFRTLLDLCRRRGFLYQSAEIYGGLRGAYDYGPLGVELKKNILNSWWRRHVYYRDDVVGVDTSIITPHPVLKASGHVDEFTDLLVDCTLTKERFRPDKAPALTLDKHGRIPITAPDKDTARLWQKALEEQFAPNVRMTVEGKHIYLYTTQVTQGDQQGRIRFEMRTAEQPALEIDYHGYVEPNSNSPFLTASRPFNLMFKTFLDPIDPIDRVIQTTLKEQEKDRSTNMIRSAVDDVLRPSTVYLRPETAQGVFVNFEQVVRTMKTKPPFGIAQVGKSFRNEIRLEHGIFRTPEFEQMELEYFVAPWESKRYFEYWRKERFNWWLEHACHPENFRQRDHAQDEMAHYATGCTDVEYNYPWGWGEVEGVAHRGNYDLTQHISNTGANFQVEDENAPTPAEKRYVPHVVESSCGLNRAMLAYLCDAFHQVQDEGKGKPPRNVLRLDPRLAPIKCAVMPLTGKQEFDPLVQKVARSLRRKGWYTVVESQKLKIGKRYYRHDEIGTPWCVTVDYQSLEDDTVTIRERDSGEQHRVPWKQVQTFIGDQLIDKDEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N878</accession>
    <name>A0A1C7N878_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">BZIP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_06646</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000412">
        <property type="protein sequence ID" value="OBZ85303.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N878"/>
    <dbReference type="STRING" id="101091.A0A1C7N878"/>
    <dbReference type="InParanoid" id="A0A1C7N878"/>
    <dbReference type="OrthoDB" id="1939598at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd14705">
        <property type="entry name" value="bZIP_Zip1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.170">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004827">
        <property type="entry name" value="bZIP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046347">
        <property type="entry name" value="bZIP_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07716">
        <property type="entry name" value="bZIP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00338">
        <property type="entry name" value="BRLZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57959">
        <property type="entry name" value="Leucine zipper domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50217">
        <property type="entry name" value="BZIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00036">
        <property type="entry name" value="BZIP_BASIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BZIP" evidence="2">
        <location>
            <begin position="138"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="30"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="46"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ85303.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="238" mass="26907" checksum="C4F6D3D64B33350E" modified="2016-11-30" version="1">MSLYMSLAPDQYHLRPMAISSITSPIGISSNSSKFGQDPMPNLCASPSSSSSQSEATSPNPMPEQNIKSGPLSPNIHRFSDSSGNSLVASISNKLSILPEPSTTHLSFFHPYRHHFAYNNANRYTNTSSSAVSLSLHERRLRNKTASAKYRAKKSQQHEEMRTTISILTKENELLIRQFEHARLENSHLKTTCDRLRGRLMAQKMLKQCLIENEQQGYFRGQMSLIYDESKNRLKETD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N895</accession>
    <name>A0A1C7N895_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Peroxisomal membrane protein 11C</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">A0J61_06597</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Peroxisome membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000406">
        <property type="protein sequence ID" value="OBZ85350.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N895"/>
    <dbReference type="STRING" id="101091.A0A1C7N895"/>
    <dbReference type="InParanoid" id="A0A1C7N895"/>
    <dbReference type="OrthoDB" id="411017at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005778">
        <property type="term" value="C:peroxisomal membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016559">
        <property type="term" value="P:peroxisome fission"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008733">
        <property type="entry name" value="PEX11"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12652">
        <property type="entry name" value="PEROXISOMAL BIOGENESIS FACTOR 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12652:SF19">
        <property type="entry name" value="PEROXISOMAL BIOGENESIS FACTOR 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05648">
        <property type="entry name" value="PEX11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0576">Peroxisome</keyword>
    <keyword evidence="1" id="KW-0962">Peroxisome biogenesis</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00046271"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OBZ85350.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="242" mass="27693" checksum="1124B3E4EC0322B5" modified="2016-11-30" version="1">MSIQQQQIQRCALPTPTASPPPEPSKIFSEKKSNRKPWPTKWLQVLQRLLKELDGRDKMMKVIQYFIKILLHYNLLKSKQWSTLASQFSMTRKVLRLGNALPSLREMRPRHDSLWNTLILSNEAVNAISDDVFCLYKLGFVGADIGYRSEMLSAYCWFAAILIDLRSAFHSHAKLCAHKADDTLEQRQKIFMAEVSIVKLMMDGIFCACDIWQPSYSSSVQAWSGFFSGALAGYKLCVKFSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N8H2</accession>
    <name>A0A1C7N8H2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_06533</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000398">
        <property type="protein sequence ID" value="OBZ85420.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N8H2"/>
    <dbReference type="STRING" id="101091.A0A1C7N8H2"/>
    <dbReference type="InParanoid" id="A0A1C7N8H2"/>
    <dbReference type="OrthoDB" id="2555519at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="17"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="117"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="290"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="27"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="123"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="290"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="310"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="326"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="342"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="357"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="399"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="427"/>
            <end position="436"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ85420.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="436" mass="48616" checksum="A5CF41CA23F7B87D" modified="2016-11-30" version="1">MSVKEVIFPKALNIVRPQTPSIRRQDSSQSSSTVSSSSPSTVSNFSSYSAFNHQQNHARVPPTIVTPSNYAYIQNNWANFKSVNPIANTVGVNPHRFLQRPRSNSNISKSTFFSARSLSSHNDDDDDDDDDLNSIDGLSDEESDDEDNDNNALTKVVAKVKNGTILNGKGQFVSKGPPQEDPNSWLEDARTNRKIADLEIEKASLLFLNSTLEAKLRQQSSQIAELQKRLQMNELPLTPVSDKHTDEFPPFDNGETRLMTEEEEIENDLTFQRIQSMVETLITQAESALTQKTKQSGRVLQQQPSSPIGDEERQHHVEETLHKLTVRSTTPSADNQLRRSKTPTINTRRSTIPNTRRVSTSDNSSTISSTSSVRSSSGTGMSRTLSRQSSPPVMTRPSSPRPFSPPPTTQPQRRSSTPKQSSQLRKQNSDKPKWSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N8L4</accession>
    <name>A0A1C7N8L4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Shugoshin C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_06544</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000400">
        <property type="protein sequence ID" value="OBZ85407.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N8L4"/>
    <dbReference type="InParanoid" id="A0A1C7N8L4"/>
    <dbReference type="OrthoDB" id="2422919at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="104"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="22"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="104"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="121"/>
            <end position="135"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ85407.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="180" mass="21245" checksum="1B68B904708052E2" modified="2016-11-30" version="1">MSLNKEMKRLSIEDTEVATRSCSQLEIDNAYLRQQNQHLNKELSFARYTINALKGITNQRDAALEETRQELENALQHIQLLTYTLRQQQRYSLSGIGLVQDTDLSDDQELSEEDEYEEQQKQQQQQQQQQLQQQQHQRRRPTVDIMSKLPLRQPSTVMTDQIFMPERHHINDAHKATVEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N9S2</accession>
    <name>A0A1C7N9S2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">60S ribosomal protein L26-1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">RPL26A_0</name>
        <name evidence="5" type="ORF">A0J61_06094</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uL24 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000351">
        <property type="protein sequence ID" value="OBZ85865.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N9S2"/>
    <dbReference type="FunCoup" id="A0A1C7N9S2">
        <property type="interactions" value="543"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N9S2"/>
    <dbReference type="InParanoid" id="A0A1C7N9S2"/>
    <dbReference type="OrthoDB" id="1688503at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015934">
        <property type="term" value="C:large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06089">
        <property type="entry name" value="KOW_RPL26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.30.30:FF:000009">
        <property type="entry name" value="60S ribosomal protein L26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005824">
        <property type="entry name" value="KOW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014722">
        <property type="entry name" value="Rib_uL2_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005825">
        <property type="entry name" value="Ribosomal_uL24_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005756">
        <property type="entry name" value="Ribosomal_uL24_euk/arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041988">
        <property type="entry name" value="Ribosomal_uL24_KOW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008991">
        <property type="entry name" value="Translation_prot_SH3-like_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01080">
        <property type="entry name" value="rplX_A_E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11143">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L26 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00467">
        <property type="entry name" value="KOW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16906">
        <property type="entry name" value="Ribosomal_L26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00739">
        <property type="entry name" value="KOW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50104">
        <property type="entry name" value="Translation proteins SH3-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01108">
        <property type="entry name" value="RIBOSOMAL_L24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 5" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="KOW" evidence="4">
        <location>
            <begin position="48"/>
            <end position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00739"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OBZ85865.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="129" mass="14699" checksum="0C76C126FB09A849" modified="2016-11-30" version="1">MKFSADVSSSRRKCRKAHFSATSDVRRKIMSAPLSKELREKHSVRSIPVRKDDEVMVVRGTYKGREGKIVQVYRKKWVIHIDRVAREKVNGATAPIGISPSKVVVTKLKLDKSRVAILERKGKKEAMKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N9U0</accession>
    <name>A0A1C7N9U0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">A0J61_06125</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000355">
        <property type="protein sequence ID" value="OBZ85820.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N9U0"/>
    <dbReference type="STRING" id="101091.A0A1C7N9U0"/>
    <dbReference type="InParanoid" id="A0A1C7N9U0"/>
    <dbReference type="OrthoDB" id="39175at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050815">
        <property type="entry name" value="TF_fung"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47338:SF5">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47338">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="7">
        <location>
            <begin position="43"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="7"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OBZ85820.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="435" mass="47710" checksum="DA0E9FD5B05669CD" modified="2016-11-30" version="1">MKKANVTPDTLQTSSHPKQRNIDINPNETRMRSSTKRPRAPIACFRCHHKKVRCDGIHPNCTRCLSTGVLCAYPSSRRSRTTQPANVDPFIDNLSQLEARIRQIEADLESQQTMIESIINSSSIPSNQESILSTTSEAKSKLLKIGIEVQESRSILAQMRLKGEQRISKSRRDAAAAAAAATSVSVAANNTHLNKRLSNQEEEKSKFTIGHNTGRQQSNTKFNCNISYNESKSFQTSYIQANSTDTKSARTNSSLYFQGMMLGSSAEFLRPYDTTPSNPTMNWSMFDQDESKSSGHHESIALVNTSPHTALVTNSNMQSISSDLYDHSALSLLDSSKDMTSMVINSIISTPSSTRSSSLASSIGFPVAVQPSNSTNSTSSNMTGASSATSYSPLDSSDNILTFNMEDVLFGSSHHGHQDIQTLPNNNPIWFYPTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NAU5</accession>
    <name>A0A1C7NAU5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_06191</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000363">
        <property type="protein sequence ID" value="OBZ85756.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NAU5"/>
    <dbReference type="InParanoid" id="A0A1C7NAU5"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ85756.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="156" mass="17870" checksum="81CA164B2F2AEE47" modified="2016-11-30" version="1">MLARKVNRAIQAYRALQKVADDLRESHTEDVLNGSFDEERSKKVEKAYHQLEVFRVASARQFPKVKEFIKEESNGGSQLQISEMPCLMGVVERLESKHGSKYRNIKGLTDHLESYCVSQGIDLDFEHEKCMPSLLGMARRVHRHAQAKSFEHQGIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NB34</accession>
    <name>A0A1C7NB34_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Putative RNA-binding protein C57A7.13</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">A0J61_05623</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000309">
        <property type="protein sequence ID" value="OBZ86327.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="FunCoup" id="A0A1C7NB34">
        <property type="interactions" value="779"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NB34"/>
    <dbReference type="InParanoid" id="A0A1C7NB34"/>
    <dbReference type="OrthoDB" id="439808at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.380">
        <property type="entry name" value="Zn-finger domain of Sec23/24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001876">
        <property type="entry name" value="Znf_RanBP2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036443">
        <property type="entry name" value="Znf_RanBP2_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13948:SF3">
        <property type="entry name" value="FI21118P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13948">
        <property type="entry name" value="RNA-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90209">
        <property type="entry name" value="Ran binding protein zinc finger-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01358">
        <property type="entry name" value="ZF_RANBP2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RRM" evidence="9">
        <location>
            <begin position="75"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="9">
        <location>
            <begin position="217"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="336"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="14"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="28"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="52"/>
            <end position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OBZ86327.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="394" mass="46068" checksum="28665444DDC2DD4B" modified="2016-11-30" version="1">MSSHSRSSSSRRDSPRRRSRSPSSRHRRDYDSHDSKRREERSHHDHHRKHDDRRGRRYEEENRYNERREQLSPNINVVLRNLPDRAREADIHKKLSQMGASIDDVSLIKDRETGESRKFAFVRFTSVGHAVQFVQRYRTFDMNSYNVRVDYSKRNNQEDEKEEWRCTKCGHFNPVSRRSCVECRQSFISAATEKRSYDTETMEINDGSKDMATMPNNILVLRQLDHLSTEESIFHSVQSFQGIYRAILIRDKLTKMSCEFAFLEFTSAQNASLALKQMGDNFRIDGRKVIASFANQESFIPVYGQSEWSIPAQNELDGLLAYWDKSSYGSAFSYAIEQERKQREEALRRVKEEEARKAQEAKASLENDLSAFYADMDDFGTDNSNDIFAVXKTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NCE3</accession>
    <name>A0A1C7NCE3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Peptidyl-tRNA hydrolase ICT1, mitochondrial</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">ict1</name>
        <name evidence="3" type="ORF">A0J61_05176</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000273">
        <property type="protein sequence ID" value="OBZ86775.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NCE3"/>
    <dbReference type="FunCoup" id="A0A1C7NCE3">
        <property type="interactions" value="131"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NCE3"/>
    <dbReference type="InParanoid" id="A0A1C7NCE3"/>
    <dbReference type="OrthoDB" id="270639at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005762">
        <property type="term" value="C:mitochondrial large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004045">
        <property type="term" value="F:peptidyl-tRNA hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016150">
        <property type="term" value="F:translation release factor activity, codon nonspecific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070126">
        <property type="term" value="P:mitochondrial translational termination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.20:FF:000046">
        <property type="entry name" value="Peptidyl-tRNA hydrolase ICT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052104">
        <property type="entry name" value="Mito_Release_Factor_mL62"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000352">
        <property type="entry name" value="Pep_chain_release_fac_I"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11075:SF54">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN ML62"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11075">
        <property type="entry name" value="PEPTIDE CHAIN RELEASE FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00472">
        <property type="entry name" value="RF-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110916">
        <property type="entry name" value="Peptidyl-tRNA hydrolase domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00745">
        <property type="entry name" value="RF_PROK_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Prokaryotic-type class I peptide chain release factors" evidence="2">
        <location>
            <begin position="46"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="142"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="151"/>
            <end position="164"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS00745"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ86775.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="171" mass="19810" checksum="6826236ED276D33A" modified="2016-11-30" version="1">MNTSFIRTLQRFYSSKAWSYREATAWQQAFNVRSIPQDHITLNFSRSSGPGGQNVNKVNTKVDLRLSLSKAHWLPDYAKQKIQTSSHLRKSKQNELIITSDKTRSQAKNIEDCYDKLVHALKDAVAVTKEPDQATLLRVQQLKHKEDQHRKAFKKKHAQKKSDRRSKGSDY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NCF1</accession>
    <name>A0A1C7NCF1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_05152</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000271">
        <property type="protein sequence ID" value="OBZ86792.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NCF1"/>
    <dbReference type="InParanoid" id="A0A1C7NCF1"/>
    <dbReference type="OrthoDB" id="2255535at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="69"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ86792.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="96" mass="11091" checksum="A4E2013D4F20669A" modified="2016-11-30" version="1">MIPEEEYGLLSQQPDEVSDNEQEEAIEFVSYAESDDDDEDPYFMPEHNKRTSTWSFLRMTCAPIQVVRFTIPTLCILIIITYTIVIGVLTEKKKSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NCF9</accession>
    <name>A0A1C7NCF9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF4097 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_05694</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000315">
        <property type="protein sequence ID" value="OBZ86256.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NCF9"/>
    <dbReference type="STRING" id="101091.A0A1C7NCF9"/>
    <dbReference type="InParanoid" id="A0A1C7NCF9"/>
    <dbReference type="OrthoDB" id="5570013at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025164">
        <property type="entry name" value="Toastrack_DUF4097"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13349">
        <property type="entry name" value="DUF4097"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF4097" evidence="2">
        <location>
            <begin position="254"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="17"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="35"/>
            <end position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13349"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ86256.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="545" mass="60299" checksum="267DDFDFE339DD37" modified="2016-11-30" version="1">MMPDSSSDSDRIPDNRITANFFGSPSVFNQANKTKKTDSNYTHNEEPYWNQPPPPYPSAGTSADPSAPPLELADNSHSLNEPYPHSPTQYQPNTPLIPSENRNHYGIIPPVHPLNTTPDTHWPWLVTPSNIGSPPPLTQPPDPQYQKKPNRWCDYFTRCLMLLFCISLGLRIMQALFGGSGAPANCSHGIVWEGLDRKLKFGNGNFEFNVVGGRLNSGHIVVKALDAADQKEGISEGTFQSVFVVSPKSLLNDPELSFTVTHHDDGIKVEVNIPHSKSSACVSLTAVVYVPRDMQRLSINAPDSNIQVRYSGKLFVKQLILSTSNSDIEMLADWEGDELALLTSNAAIEVSNKLYAKQEIIVYTSNGMLLFKDDVRAHKQIELNNKNGDIRSESTLTTHSLAVYNTYGHIKLSEANVDLGMVKTLEGHIDIDVCTVNSTLNAQTNKGHLAMRIQGANDVHVYAYTGEGTLSIDMPFEFEGIFSFETDTIESLSLLDPYRWAHIERVNYGRVCGTRYRTRGTGKHPDGNLSAISLKGELQIVFTPT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NCP1</accession>
    <name>A0A1C7NCP1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF8032 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_05062</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000263">
        <property type="protein sequence ID" value="OBZ86892.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NCP1"/>
    <dbReference type="STRING" id="101091.A0A1C7NCP1"/>
    <dbReference type="InParanoid" id="A0A1C7NCP1"/>
    <dbReference type="OrthoDB" id="5599902at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058345">
        <property type="entry name" value="DUF8032"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22949:SF0">
        <property type="entry name" value="RE27538P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22949">
        <property type="entry name" value="WHITE COLLAR 2 PROTEIN WC2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26087">
        <property type="entry name" value="DUF8032"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF8032" evidence="2">
        <location>
            <begin position="272"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="125"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="142"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="184"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="210"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="237"/>
            <end position="246"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF26087"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ86892.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="398" mass="44465" checksum="9E771AE4AA536C42" modified="2016-11-30" version="1">MAPFPCREQAKYHLEATLSWPTLVAPENQSNFQPPQQHDLMHTLNSTELDMSSLVGVDQTLWPISGPDTNQFNDTSSQQAIASSLDPLFWNTSRGIHVPPTIKEDWPLSNTVFMQHQPVPYQHQFVLPPTPPVSSPNTHVNSLLPSSLSSSSSTSSASSTTTTTLSNCKRNSVTELGSMHREITPSTPISSSPNGNSLSPPPLVSVIPQSKLTSSSSTPTIKSRGPGRRKSADSHHTPTRTYRRRASSQPSVASVVSLSAHEPVARIIDGIEHITFLYSHDRLVKEYTVRTDVESVCLDHIPISFRVQNAIYPRANVSREEYDGNRWEYETSCNKLGWELCWLNQDQLCGRRGLIQRAVDSYRNRHAEMRSRRVTRQEKVANGTLRKRRAKKSHSALL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NCY6</accession>
    <name>A0A1C7NCY6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Pentatricopeptide repeat-containing protein-mitochondrial domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">A0J61_05126</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Regulates mitochondrial small subunit maturation by controlling 15S rRNA 5'-end processing. Localizes to the 5' precursor of the 15S rRNA in a position that is subsequently occupied by mS47 in the mature yeast mtSSU. Uses structure and sequence-specific RNA recognition, binding to a single-stranded region of the precursor and specifically recognizing bases -6 to -1. The exchange of Ccm1 for mS47 is coupled to the irreversible removal of precursor rRNA that is accompanied by conformational changes of the mitoribosomal proteins uS5m and mS26. These conformational changes signal completion of 5'-end rRNA processing through protection of the mature 5'-end of the 15S rRNA and stabilization of mS47. The removal of the 5' precursor together with the dissociation of Ccm1 may be catalyzed by the 5'-3' exoribonuclease Pet127. Involved in the specific removal of group I introns in mitochondrial encoded transcripts.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Binds to mitochondrial small subunit 15S rRNA.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the CCM1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000269">
        <property type="protein sequence ID" value="OBZ86820.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NCY6"/>
    <dbReference type="STRING" id="101091.A0A1C7NCY6"/>
    <dbReference type="InParanoid" id="A0A1C7NCY6"/>
    <dbReference type="OrthoDB" id="185373at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002885">
        <property type="entry name" value="PPR_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057027">
        <property type="entry name" value="TPR_mt"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00756">
        <property type="entry name" value="PPR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47447">
        <property type="entry name" value="OS03G0856100 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47447:SF17">
        <property type="entry name" value="OS12G0638900 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13812">
        <property type="entry name" value="PPR_3"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23276">
        <property type="entry name" value="TPR_24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51375">
        <property type="entry name" value="PPR"/>
        <property type="match status" value="5"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="PPR" evidence="5">
        <location>
            <begin position="88"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="repeat" description="PPR" evidence="5">
        <location>
            <begin position="158"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="domain" description="Pentatricopeptide repeat-containing protein-mitochondrial" evidence="6">
        <location>
            <begin position="267"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="repeat" description="PPR" evidence="5">
        <location>
            <begin position="372"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="repeat" description="PPR" evidence="5">
        <location>
            <begin position="407"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="repeat" description="PPR" evidence="5">
        <location>
            <begin position="442"/>
            <end position="476"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00044493"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00044511"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00708"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF23276"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OBZ86820.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="521" mass="59012" checksum="0B4F0567BF8CAC0A" modified="2016-11-30" version="1">MNRLLLAKSNTSLLARQQWVVNSSKFVRFNTTEAVSKKIILQGHPTAPLSAFNYRLATQLRQKSDPRINLNKVLKIVDEIKAQNIKFNQFTYNAILTAYSRTKDKGSIMKTLDEMKDGGMTPLLDSYNIALEAFANAGDLENLDTLRREMKEKNLDLTATSYQHLIRGLSNAGKLDRAMEVFAEMKQAGIEANLKSYSVIVSACYRYSEAKIAFDMLKQAEEAGLPVESEPRIYMDVMRVGSNEDETDIVKYCWEKAIGTHSLRPDEGTLLNVLRVAAKAGDTKLATDTIRQLSTSGYPYKEHYFTPLMEAFIVKDDLKSAFNVLDIMRLSGIPPTMRATLPIRSKLNRDIESVDKAYYLLEEMKKENKTVDISAFNAVVAACADAKDLNRTIATYREAANLGVIPNVDTYNCVLDACIHTRMKGMGQIVIDEMKKAEITPNLDTYSKMMALACTQKNYEDAFVFLEEMKSYDVVPPQHCYYSLAQKLAYEKDPRFHMVLEEMETFGYKVSARTRALWRAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7ND08</accession>
    <name>A0A1C7ND08_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Cytochrome c oxidase subunit 4, mitochondrial</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Cytochrome c oxidase polypeptide IV</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="primary">cox4</name>
        <name evidence="12" type="ORF">A0J61_04961</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
            <orientation evidence="1">Matrix side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the cytochrome c oxidase subunit 5B family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000255">
        <property type="protein sequence ID" value="OBZ86993.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7ND08"/>
    <dbReference type="FunCoup" id="A0A1C7ND08">
        <property type="interactions" value="278"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7ND08"/>
    <dbReference type="InParanoid" id="A0A1C7ND08"/>
    <dbReference type="OrthoDB" id="10249250at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045277">
        <property type="term" value="C:respiratory chain complex IV"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004129">
        <property type="term" value="F:cytochrome-c oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990145">
        <property type="term" value="P:maintenance of translational fidelity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006123">
        <property type="term" value="P:mitochondrial electron transport, cytochrome c to oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033617">
        <property type="term" value="P:mitochondrial respiratory chain complex IV assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd00924">
        <property type="entry name" value="Cyt_c_Oxidase_Vb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.11.10:FF:000003">
        <property type="entry name" value="Cytochrome c oxidase subunit IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.11.10">
        <property type="entry name" value="Cytochrome c oxidase, subunit Vb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002124">
        <property type="entry name" value="Cyt_c_oxidase_su5b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036972">
        <property type="entry name" value="Cyt_c_oxidase_su5b_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10122:SF0">
        <property type="entry name" value="CYTOCHROME C OXIDASE SUBUNIT 5B, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10122">
        <property type="entry name" value="CYTOCHROME C OXIDASE SUBUNIT 5B, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01215">
        <property type="entry name" value="COX5B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57802">
        <property type="entry name" value="Rubredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51359">
        <property type="entry name" value="COX5B_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="4" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="5 11" id="KW-0862">Zinc</keyword>
    <feature type="binding site" evidence="11">
        <location>
            <position position="106"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="114"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="130"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="133"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010292"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00031366"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00070613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR602124-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="OBZ86993.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="150" mass="16315" checksum="A1C90E3111512C2D" modified="2016-11-30" version="1">MLALRRAAIKAAPLATRASVRPFSVLGARFSGAVGHNVESSLGPGGKAGEVPTDLEQATGLERAELLLKLQGKELFDMEPLDMTHKGTPKNPIVVKSHDAIRQVGCTGYPVESHDVIWINLDKSHEHDRCPECGSVFKMDFVGSEEEHHH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NDW5</accession>
    <name>A0A1C7NDW5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">NADPH-dependent 1-acyldihydroxyacetone phosphate reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">ayr1</name>
        <name evidence="6" type="ORF">A0J61_04989</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000257">
        <property type="protein sequence ID" value="OBZ86959.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NDW5"/>
    <dbReference type="FunCoup" id="A0A1C7NDW5">
        <property type="interactions" value="107"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NDW5"/>
    <dbReference type="InParanoid" id="A0A1C7NDW5"/>
    <dbReference type="OrthoDB" id="2102561at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05374">
        <property type="entry name" value="17beta-HSD-like_SDR_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000261">
        <property type="entry name" value="NADPH-dependent 1-acyldihydroxyacetone phosphate reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44169">
        <property type="entry name" value="NADPH-DEPENDENT 1-ACYLDIHYDROXYACETONE PHOSPHATE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44169:SF6">
        <property type="entry name" value="NADPH-DEPENDENT 1-ACYLDIHYDROXYACETONE PHOSPHATE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="241"/>
            <end position="266"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OBZ86959.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="281" mass="30415" checksum="54AAD6DD2FFE06AB" modified="2016-11-30" version="1">MVEKIVLVTGCSQGGIGYSLAKQFAQQGNHVIATARRLEALDGLEAFGCDKEVLDITDKNSIDSLVKKAIDKYEHIDILVNNAGAPAYGALLDIDMAVVEQCVNTNIYGTLAMCKVVGRHMAERRQGKIVNIGSVVGYRSTPWASIYAMSKAAVHSLSDALRMELSPFGVQVVVVAPGAITSNIGNNGSKTTHVPEDSIYKSVAKFIHGRANSSQGPSSTPTDVFASHIVKKTLQKNTPSYVTYGHLSFLFVIFYYLPSFVADWILSNKFGLALLKRAKQD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NEC0</accession>
    <name>A0A1C7NEC0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">cytochrome-b5 reductase</fullName>
            <ecNumber evidence="2">1.6.2.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">CBR1_0</name>
        <name evidence="8" type="ORF">A0J61_04502</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 6">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.6.2.2" evidence="2"/>
    <dbReference type="EMBL" id="LUGH01000222">
        <property type="protein sequence ID" value="OBZ87442.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NEC0"/>
    <dbReference type="STRING" id="101091.A0A1C7NEC0"/>
    <dbReference type="InParanoid" id="A0A1C7NEC0"/>
    <dbReference type="OrthoDB" id="432685at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090524">
        <property type="term" value="F:cytochrome-b5 reductase activity, acting on NADH"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.10">
        <property type="entry name" value="Translation factors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001834">
        <property type="entry name" value="CBR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008333">
        <property type="entry name" value="Cbr1-like_FAD-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017938">
        <property type="entry name" value="Riboflavin_synthase-like_b-brl"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19370">
        <property type="entry name" value="NADH-CYTOCHROME B5 REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19370:SF171">
        <property type="entry name" value="NADH-CYTOCHROME B5 REDUCTASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00970">
        <property type="entry name" value="FAD_binding_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63380">
        <property type="entry name" value="Riboflavin synthase domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0274">FAD</keyword>
    <keyword evidence="3 6" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Flavoprotein pyridine nucleotide cytochrome reductase-like FAD-binding" evidence="7">
        <location>
            <begin position="11"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="62"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="63"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="64"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR601834-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OBZ87442.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="81" mass="9319" checksum="C17321C7578175AF" modified="2016-11-30" version="1">MVFSPSEFRSFKLEKVERVNHNVSLFRFKLPKETDVSNLPITSCVMFRSNVVKDGKTEEVIRPYTPTSHEKLGSNGLFMLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NEG3</accession>
    <name>A0A1C7NEG3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Protein MEF2BNB</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">A0J61_06201</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Lysosome membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the BORCS8 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000364">
        <property type="protein sequence ID" value="OBZ85744.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NEG3"/>
    <dbReference type="InParanoid" id="A0A1C7NEG3"/>
    <dbReference type="OrthoDB" id="10044187at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019320">
        <property type="entry name" value="BORCS8"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21146:SF0">
        <property type="entry name" value="BLOC-1-RELATED COMPLEX SUBUNIT 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21146">
        <property type="entry name" value="MEF2B PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10167">
        <property type="entry name" value="BORCS8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0458">Lysosome</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004656"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010463"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023228"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OBZ85744.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="159" mass="18185" checksum="F93FCE4F683A2D79" modified="2016-11-30" version="1">MTSKSLLIPTQKKERPASICSATSSSSARSYSWTAAFSLDQLSLYSKKTFGEQEEKKKRRQQERIKQIAGGFNHILLLSLNDCSVGLYRVLDHIHRRIPKIVETKKKVRSSSQRVETAILDIEDVRKNVCELEQIESFFNISQMIEQSIAIVKKPTDIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NEM5</accession>
    <name>A0A1C7NEM5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_04374</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000213">
        <property type="protein sequence ID" value="OBZ87573.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NEM5"/>
    <dbReference type="InParanoid" id="A0A1C7NEM5"/>
    <dbReference type="OrthoDB" id="2201545at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ87573.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="114" mass="13128" checksum="BBDB6FBDBC5D900B" modified="2016-11-30" version="1">MHPFFKFLDHYTGFPASNIPESCNLSTLLELLLSTGFSAIPDNHWIVTKRPRYPHLEFRPDHIVSAFWSEQASPTPFRLLCTASLRASWVSHWAFVRQSTTFTESVVISKMKCL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NES8</accession>
    <name>A0A1C7NES8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_04382</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000213">
        <property type="protein sequence ID" value="OBZ87568.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NES8"/>
    <dbReference type="InParanoid" id="A0A1C7NES8"/>
    <dbReference type="OrthoDB" id="2242118at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ87568.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="260" mass="30233" checksum="EBF43E531B4BEC62" modified="2016-11-30" version="1">MSRQSFSYFRYLSSHFKPKRPQLFSSSSSITSSVSGNSVQTPITESIYFDIEEYDGSSIEQQDFCIIDTVETMSTKQILNLINKQPVADWYQTDLVDEFTTLLNETKSVCHRLDRCRKTIQFAHTKDAISLDLMHIVHFIRERYAHHSSFVTLMGLLMIVIQVLKTEDEVQRQLLDEAHIGRIIILWMVQILSVKVTGFHDLQVPLFQVVLDCHPTDTDHPVWLPALKSVCLQLARRDPTWEQREEYTKVYSIVTHLLLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NF08</accession>
    <name>A0A1C7NF08_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Transmembrane protein 19</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">tmem19</name>
        <name evidence="7" type="ORF">A0J61_06026</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TMEM19 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000345">
        <property type="protein sequence ID" value="OBZ85914.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NF08"/>
    <dbReference type="STRING" id="101091.A0A1C7NF08"/>
    <dbReference type="InParanoid" id="A0A1C7NF08"/>
    <dbReference type="OrthoDB" id="30881at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002794">
        <property type="entry name" value="DUF92_TMEM19"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13353">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13353:SF5">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01940">
        <property type="entry name" value="DUF92"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="6"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="39"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="88"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="121"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="185"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OBZ85914.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="206" mass="22138" checksum="502FB69C759B60C4" modified="2016-11-30" version="1" fragment="single">SSERNAVQVACNGLMGGLAVFWFQLYCEPFSTSCFHQARWSLIFLWAYVGHYACCAGDTWASELGILNKDWPILITRMEKVPPGTNGAVSLLGLTASLAGGALVGFSAALTLYLEQACYGFAWELIVLGSLAGLGGSMIDSLLGATVQESIYSEDQKKIVSKVNQGERTRVICGKAILDNHQVNLVTSVSTTILCALLAYSLYPIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NFA7</accession>
    <name>A0A1C7NFA7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Protein Tob1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">Tob1</name>
        <name evidence="4" type="ORF">A0J61_04176</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the BTG family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000198">
        <property type="protein sequence ID" value="OBZ87767.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NFA7"/>
    <dbReference type="STRING" id="101091.A0A1C7NFA7"/>
    <dbReference type="InParanoid" id="A0A1C7NFA7"/>
    <dbReference type="OrthoDB" id="19928at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.640.90">
        <property type="entry name" value="Anti-proliferative protein, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002087">
        <property type="entry name" value="Anti_prolifrtn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033332">
        <property type="entry name" value="BTG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036054">
        <property type="entry name" value="BTG-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22978">
        <property type="entry name" value="B-CELL TRANSLOCATION GENE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22978:SF22">
        <property type="entry name" value="BTG FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07742">
        <property type="entry name" value="BTG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00310">
        <property type="entry name" value="ANTIPRLFBTG1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00099">
        <property type="entry name" value="btg1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160696">
        <property type="entry name" value="BTG domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Anti-proliferative protein" evidence="3">
        <location>
            <begin position="1"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="126"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="131"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="145"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="187"/>
            <end position="200"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00099"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OBZ87767.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="200" mass="22547" checksum="0C375EDF4EF86B9B" modified="2016-11-30" version="1">MHMEIAQAVDFLGRLLQSKLDSDIIARYKQTLSNLLAIRFKDHWDTQQPYRGNGFRALTNFNGQLDPVLVQAAIQAHIQIDRIDVHLPRDFVLWIDPFSVSYRVGDHGNIMTLFEDRSRGRVTFKLDPHHSSPSSLHSLSSPASTPQQTNAILSPSNSPMLSYVQPKSTPIRISPPNSPDSIVLLNKKKEDNKKDLVLAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NFQ7</accession>
    <name>A0A1C7NFQ7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">AAA+ ATPase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">A0J61_04363</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the AAA ATPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000212">
        <property type="protein sequence ID" value="OBZ87579.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NFQ7"/>
    <dbReference type="STRING" id="101091.A0A1C7NFQ7"/>
    <dbReference type="InParanoid" id="A0A1C7NFQ7"/>
    <dbReference type="OrthoDB" id="10254455at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:001054">
        <property type="entry name" value="ATPase, AAA family, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050168">
        <property type="entry name" value="AAA_ATPase_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041569">
        <property type="entry name" value="AAA_lid_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003960">
        <property type="entry name" value="ATPase_AAA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23077">
        <property type="entry name" value="AAA-FAMILY ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23077:SF27">
        <property type="entry name" value="ATPASE FAMILY GENE 2 PROTEIN HOMOLOG A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17862">
        <property type="entry name" value="AAA_lid_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00674">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="6">
        <location>
            <begin position="22"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="domain" description="AAA+ ATPase" evidence="6">
        <location>
            <begin position="257"/>
            <end position="393"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OBZ87579.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="467" mass="51991" checksum="A19359469DE30A75" modified="2016-11-30" version="1">MEKKALGTLDQAFELTFNQKESPFTILLKGDSGVGKTFTVHKLAAKYNIKVHCLTLGNLAADYRGQLSKGFKRILWHMNPQDLLLIEDIDCFFPQHGDTQDSALISLFTQMIQTHQIMVIATTRHPDRLATEIYPLFTDQIQFDIPTPEERTQMLSICLAQDTLDLKSLAARAHAFVAADLAQWCQRARVRADGRALSMDDLEAVLDMTKKGMMAERPDPVYWREIGGLTEAKQALEESAVWVYRHADAYRRLGIRPSKGLLLFGPPGTGKTLLAKAVATESSANFLSIRIPDLIKGEVGESEKAVSKIFRTAIRCSPCVVFFDELEAIFASRDTSGDVGRKLISQFLIEMDHLDRMDQSVIILGATNHPEAIDDSILRPGRLDRLVFVGPPNLDERIQILEVLKHTTKLSSNIDLAWVGAQTEGYTGADLKAVLRKAGLLALKNNRHCIEQQDIQASLSYVTPSCS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NGC2</accession>
    <name>A0A1C7NGC2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Vacuolar amino acid transporter 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">AVT1_0</name>
        <name evidence="11" type="ORF">A0J61_03796</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the amino acid/polyamine transporter 2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000172">
        <property type="protein sequence ID" value="OBZ88152.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NGC2"/>
    <dbReference type="STRING" id="101091.A0A1C7NGC2"/>
    <dbReference type="InParanoid" id="A0A1C7NGC2"/>
    <dbReference type="OrthoDB" id="655540at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005774">
        <property type="term" value="C:vacuolar membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015179">
        <property type="term" value="F:L-amino acid transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013057">
        <property type="entry name" value="AA_transpt_TM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22950">
        <property type="entry name" value="AMINO ACID TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22950:SF692">
        <property type="entry name" value="TRANSMEMBRANE AMINO ACID TRANSPORTER FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01490">
        <property type="entry name" value="Aa_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0029">Amino-acid transport</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="121"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="146"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="193"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="226"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="251"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="300"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="331"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="379"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="424"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="450"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="483"/>
            <end position="501"/>
        </location>
    </feature>
    <feature type="domain" description="Amino acid transporter transmembrane" evidence="10">
        <location>
            <begin position="113"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="52"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="65"/>
            <end position="84"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008066"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF01490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="OBZ88152.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="505" mass="55890" checksum="B92895019E413A43" modified="2016-11-30" version="1">MSNNLNIPNLHPSLRDQSLDEQELSGSFKDRFDDFVGSYSRASMMHMAENVMVSEGSERDEEDTISTYSSNQRRNSEGTLSEQTPLLPPLSKVDTCQSVMTVGDSYHTSPQIKKSSFLQSIFNSINILIGVGILSLPLGFKCSGWIISLIVFCFCFGLTNYTAKLLAKCLDKDPNSRTYGDMGAMAFGVRGRVFISFLFLTELVTCSVALVVLLCDGIDSLFPGQNPFLIRVISFVILTPTLFIPIRHLSYTSLLGILSVFSLFAVIVYDGLSKPNAPGSLHEMEPTATLFPQADSNVPLSFGLIMAGFAGHAVFPTIYRDMKHPEEYKKMVNFTYIVTATVYLAVAACGYAMFGSSTMQEITQNLVLVPEYNKVLNRMAVYLIALNPIAKYGLTLNPVVLSWQMSLLPTLESWTNKAKWRKPLVKCIGILMTSVLIITLATLIPNFDKVMSLLGALFSFLISGIFPIFCYLKLFKLGFWERVMNVILVSIAIVMGTVGTVKSFI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NGF5</accession>
    <name>A0A1C7NGF5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Ammonium transporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">amt1_1</name>
        <name evidence="10" type="ORF">A0J61_03885</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cell membrane</location>
            <topology evidence="8">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the ammonia transporter channel (TC 1.A.11.2) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000177">
        <property type="protein sequence ID" value="OBZ88070.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NGF5"/>
    <dbReference type="STRING" id="101091.A0A1C7NGF5"/>
    <dbReference type="InParanoid" id="A0A1C7NGF5"/>
    <dbReference type="OrthoDB" id="534912at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008519">
        <property type="term" value="F:ammonium channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.3430.10:FF:000011">
        <property type="entry name" value="Ammonium transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3430.10">
        <property type="entry name" value="Ammonium transporter AmtB like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029020">
        <property type="entry name" value="Ammonium/urea_transptr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001905">
        <property type="entry name" value="Ammonium_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018047">
        <property type="entry name" value="Ammonium_transpt_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024041">
        <property type="entry name" value="NH4_transpt_AmtB-like_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00836">
        <property type="entry name" value="amt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43029">
        <property type="entry name" value="AMMONIUM TRANSPORTER MEP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43029:SF10">
        <property type="entry name" value="AMMONIUM TRANSPORTER MEP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00909">
        <property type="entry name" value="Ammonium_transp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111352">
        <property type="entry name" value="Ammonium transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01219">
        <property type="entry name" value="AMMONIUM_TRANSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8" id="KW-0924">Ammonia transport</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 8" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="27"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="59"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="113"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="146"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="180"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="213"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="246"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="274"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="297"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="330"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="384"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="domain" description="Ammonium transporter AmtB-like" evidence="9">
        <location>
            <begin position="27"/>
            <end position="436"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU362002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00909"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OBZ88070.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="574" mass="61586" checksum="49C617B569AD9ECC" modified="2016-11-30" version="1">MADNSTLAATDGTGHAASYAINAGDTAWVMICACLVFIMSPALGLFYAGLARAKNALSLMYLTVLSVAVVSFQWYLIGYSLTFSETGSNFIGDSTHFLLRGVGTKPAFEGQTIPASAFMIFQAMFAAITPALAFGSAAERMSLGPAILFIFIWTTLVYDVITNWVWASNGWLAKLGIMDYAGGIPVHISSGLGAFAYALVLGKRRDYHKNANAPHNVTFVFLGLALMWFGWFAFNAGSALAANARSVNSLVATHISACTAAIVWVLLDYLKTRKWSIIGLCTGAVAGLATITPGSGFVTPSSALAFGALGSLVCYIAIHYKHKMGIDDCLDVFGVHYVGGLVGLILTGIFAERAVIALGFPEGTPLDDIPIGGWLDGNWKQVPVQLAGIAAVSIWSFVVTYIILMVINQVPSLYLRLADEDEIVGTDWAEMGERAYGYLDYEEAEAVTPDNINGHTLDNSKKQNIHVARLKRLLMIDRSTVIRGAPDLVEAPVMDYGQQKDLGAYDLHSLKPPIPSPTNEVIIQNVQVNQIDDSNSLQHKPTLHHTSSNDDTIQVLSSANETPLGSSSNSAKSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NGQ2</accession>
    <name>A0A1C7NGQ2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Non-canonical poly(A) RNA polymerase PAPD5</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">PAPD5</name>
        <name evidence="2" type="ORF">A0J61_03737</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000167">
        <property type="protein sequence ID" value="OBZ88215.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NGQ2"/>
    <dbReference type="STRING" id="101091.A0A1C7NGQ2"/>
    <dbReference type="InParanoid" id="A0A1C7NGQ2"/>
    <dbReference type="OrthoDB" id="273917at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031499">
        <property type="term" value="C:TRAMP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990817">
        <property type="term" value="F:poly(A) RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043634">
        <property type="term" value="P:polyadenylation-dependent ncRNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031123">
        <property type="term" value="P:RNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1410.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043519">
        <property type="entry name" value="NT_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045862">
        <property type="entry name" value="Trf4-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23092:SF15">
        <property type="entry name" value="INACTIVE NON-CANONICAL POLY(A) RNA POLYMERASE PROTEIN TRF4-2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23092">
        <property type="entry name" value="POLY(A) RNA POLYMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81301">
        <property type="entry name" value="Nucleotidyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81631">
        <property type="entry name" value="PAP/OAS1 substrate-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="308"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="329"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="357"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="406"/>
            <end position="418"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ88215.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="418" mass="48336" checksum="53D7EAF2030F4102" modified="2016-11-30" version="1">MDAPWSNKETLRTTNKLERLSKEIVDFEKYIAPTQKEQLNRDTLLYSVSQLIESLWPGNVIAPFGSSVTGLQFPSRLIPHAKVPVLMATDDNNVSMDITVQNESPSSDRTVLWIKEYPLLKTLFMVLKQVLSNYRVSSLPTFEPLSAKTAGLASYSLICMIVSYLQLQAPKSHDPSRPEYIAETLLGFLDFYSRFDSSLYAISLIDGGAYLTADYSPIGIDPKEGKLTIIDPDVPGANVARSTLRFDILKLIFARAHSDLRKRLDSSTKGESILSSVLLVKPHYYGEPRSEGTRFKKEEIWIDTGLPSNANEKRSRFRPHAVTHVAAGKRNEERRNASSRDERRYNPYQSRNKSHNNTREDRYEREDRYQRKDSYRRENYHEKESRYQKEYERHARNNHSHLAEHYKKKADRAKRNHF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NGT5</accession>
    <name>A0A1C7NGT5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Heat shock protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">hsp30_2</name>
        <name evidence="6" type="ORF">A0J61_03725</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2 3">Belongs to the small heat shock protein (HSP20) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000166">
        <property type="protein sequence ID" value="OBZ88228.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NGT5"/>
    <dbReference type="FunCoup" id="A0A1C7NGT5">
        <property type="interactions" value="189"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NGT5"/>
    <dbReference type="InParanoid" id="A0A1C7NGT5"/>
    <dbReference type="OrthoDB" id="1431247at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06464">
        <property type="entry name" value="ACD_sHsps-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.790">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002068">
        <property type="entry name" value="A-crystallin/Hsp20_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008978">
        <property type="entry name" value="HSP20-like_chaperone"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031107">
        <property type="entry name" value="Small_HSP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11527">
        <property type="entry name" value="HEAT-SHOCK PROTEIN 20 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00011">
        <property type="entry name" value="HSP20"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49764">
        <property type="entry name" value="HSP20-like chaperones"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01031">
        <property type="entry name" value="SHSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 6" id="KW-0346">Stress response</keyword>
    <feature type="domain" description="SHSP" evidence="5">
        <location>
            <begin position="46"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="94"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="97"/>
            <end position="111"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003616"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS01031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OBZ88228.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="188" mass="21288" checksum="F718FC84202E95E4" modified="2016-11-30" version="1">MAVSHRLFSDALRDIQNAMAVFDQPFFSNPLLNEGFASNFGKLTRQSDSFVYSPATDVVEKPDAYELHAEIPGYEKKDIKIEVNDGRTLVLTGSKQKQTDQKAEFEKKQEENGSQEQQVIREPEEKGTQAAANSKWWINERIGGSFSRSFTFPDQIDIEQVKASYENGVLKVIIPKVANRQSRLVDID</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NGY9</accession>
    <name>A0A1C7NGY9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Subtilase-type proteinase psp3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">psp3</name>
        <name evidence="8" type="ORF">A0J61_03591</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5 6">Belongs to the peptidase S8 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000157">
        <property type="protein sequence ID" value="OBZ88367.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NGY9"/>
    <dbReference type="STRING" id="101091.A0A1C7NGY9"/>
    <dbReference type="InParanoid" id="A0A1C7NGY9"/>
    <dbReference type="OrthoDB" id="206201at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04077">
        <property type="entry name" value="Peptidases_S8_PCSK9_ProteinaseK_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.200:FF:000007">
        <property type="entry name" value="Subtilisin-like serine protease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.200">
        <property type="entry name" value="Peptidase S8/S53 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034193">
        <property type="entry name" value="PCSK9_ProteinaseK-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000209">
        <property type="entry name" value="Peptidase_S8/S53_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036852">
        <property type="entry name" value="Peptidase_S8/S53_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023827">
        <property type="entry name" value="Peptidase_S8_Asp-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022398">
        <property type="entry name" value="Peptidase_S8_His-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023828">
        <property type="entry name" value="Peptidase_S8_Ser-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050131">
        <property type="entry name" value="Peptidase_S8_subtilisin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015500">
        <property type="entry name" value="Peptidase_S8_subtilisin-rel"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43806:SF11">
        <property type="entry name" value="CEREVISIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43806">
        <property type="entry name" value="PEPTIDASE S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00082">
        <property type="entry name" value="Peptidase_S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00723">
        <property type="entry name" value="SUBTILISIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52743">
        <property type="entry name" value="Subtilisin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51892">
        <property type="entry name" value="SUBTILASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00136">
        <property type="entry name" value="SUBTILASE_ASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00137">
        <property type="entry name" value="SUBTILASE_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00138">
        <property type="entry name" value="SUBTILASE_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 5 6" id="KW-0645">Protease</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5 6" id="KW-0720">Serine protease</keyword>
    <feature type="domain" description="Peptidase S8/S53" evidence="7">
        <location>
            <begin position="106"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="5">
        <location>
            <position position="115"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="5">
        <location>
            <position position="147"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="5">
        <location>
            <position position="299"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003355"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OBZ88367.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="360" mass="39387" checksum="8EC8A571790E34F8" modified="2016-11-30" version="1">MTERYYDRRRSFPAPESIDFLSVGSNFTLIAGRFSDDSFVKYLHQLQDVEYVEQNHVYQIQIEQNELRKRQLLKSEIAANWGLARIAQRQKINSTLLQYTFDEQAGQDVHVYVMDTGVDISHQDFENRAIFEANFVETEGHVDMNGHGTHVASKVVGKHFGVAKKAVVHSIKVLNKDGDGMLSNIIKGINHVIETATPGKSVINLSLNGPKSFALDEILSKLVLDHQIPVFVAAGNSGSDACLFSPSSNPNVFSVGASDANDEAAPFSNSGRCVEIYAPGSGIESAYIGGLTKKLDGTSMASPHVTGIAASLLSRKAYANVKDLYDDVILSATQNALSFQPNVDVNSNYNRLAYLNTTPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NH82</accession>
    <name>A0A1C7NH82_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">60S ribosomal protein L4-B</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">rpl4b</name>
        <name evidence="5" type="ORF">A0J61_03469</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uL4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000150">
        <property type="protein sequence ID" value="OBZ88482.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NH82"/>
    <dbReference type="FunCoup" id="A0A1C7NH82">
        <property type="interactions" value="572"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NH82"/>
    <dbReference type="InParanoid" id="A0A1C7NH82"/>
    <dbReference type="OrthoDB" id="10259785at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.1370.10:FF:000002">
        <property type="entry name" value="60S ribosomal protein L4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1370.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025755">
        <property type="entry name" value="Ribos_uL4_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002136">
        <property type="entry name" value="Ribosomal_uL4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023574">
        <property type="entry name" value="Ribosomal_uL4_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013000">
        <property type="entry name" value="Ribosomal_uL4_euk/arc_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045240">
        <property type="entry name" value="Ribosomal_uL4_euk/arch"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19431">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14374">
        <property type="entry name" value="Ribos_L4_asso_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00573">
        <property type="entry name" value="Ribosomal_L4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52166">
        <property type="entry name" value="Ribosomal protein L4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00939">
        <property type="entry name" value="RIBOSOMAL_L1E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 5" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Large ribosomal subunit protein uL4 C-terminal" evidence="4">
        <location>
            <begin position="274"/>
            <end position="348"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF14374"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OBZ88482.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="376" mass="41400" checksum="428247BDAE35E3C8" modified="2016-11-30" version="1">MSAARPVLNVYDNGKNVATTVPLPAVFKAPIRPDIVNFVHTNMAKNKRQPYAVSSKAGEQTSAESWGTGRAVARIPRVNGSGTHRAGQAAFGNMCRGGRMFAPTKTWRKWHIKTNLNQKRFATASALAASALPALVMARGHRVEKIEEVPLVVSDSVQQLTKTKDAVALLKAINAYSDVVKVSNSRKLRAGQGKLRNRRHRQRRGPLVIYDEDNGLVKAFRNLPGLELVNVRRLNLLQLAPGGHLGRFIIWTQSAVALLDELYGTYEAPATLKKDYVLPAHIMTNPDVARLINSDEIQSVVRPAGNKVHKRPFTQKKNPLKNQGVMNRLNPYAQVLRRAELVKAEKAAAGKVTKTQKKRGASTAASKKFLETLHQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NHQ0</accession>
    <name>A0A1C7NHQ0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Protein phosphatase 1 regulatory subunit 7</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">ppp1r7</name>
        <name evidence="4" type="ORF">A0J61_03382</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000144">
        <property type="protein sequence ID" value="OBZ88565.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NHQ0"/>
    <dbReference type="InParanoid" id="A0A1C7NHQ0"/>
    <dbReference type="OrthoDB" id="1517790at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025875">
        <property type="entry name" value="Leu-rich_rpt_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003591">
        <property type="entry name" value="Leu-rich_rpt_typical-subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050836">
        <property type="entry name" value="SDS22/Internalin_LRR"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46652:SF7">
        <property type="entry name" value="LEUCINE-RICH REPEAT AND IQ DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46652">
        <property type="entry name" value="LEUCINE-RICH REPEAT AND IQ DOMAIN-CONTAINING PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12799">
        <property type="entry name" value="LRR_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14580">
        <property type="entry name" value="LRR_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00369">
        <property type="entry name" value="LRR_TYP"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="307"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="425"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="321"/>
            <end position="340"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OBZ88565.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="445" mass="50973" checksum="9590EBFDE046D6C7" modified="2016-11-30" version="1">MKLTRNLLTEIYPDQPLENLKDIKVTGKDVSQIEDISFCKELRKLNLSNNQLANEQSIVGLRDLEKLTLLNLSHNQFKDFTGFQHFQILHVLNLSNNELVHMSPHLTRLKQLKALILSNNDLLEVENIEPLLQLNTLVIXHNKIDTVPRLSSLAELTKLSAAHNQLSQVPDLTYNVLLKELRLNDNQIKQIPETLRKCSAIEILDFGNNQLAEWSDIAPIGSLLHLHNLNLKGNPITKKKDYLEKVLDLVPSLRILDGERFDPKFLLRKKKQRENVNLLEKKQRLKRIKLQKEKKEKKKLDAEGDVLMDELVSRPSKQRKTKEEPVKSKRSSDTSEDKPVLKKKKKTNDKDMFFLKPEEKKKIQKEVKVETKVEVKVEKPKKAVEPVLPTPVTKAQTGVLGVVDKTKKIKSKKATTTNDVVAELEKEKKEKESNTGTGLDVGGWD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NHU6</accession>
    <name>A0A1C7NHU6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Arrestin domain-containing protein C31A2.12</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_03384</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000144">
        <property type="protein sequence ID" value="OBZ88560.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NHU6"/>
    <dbReference type="FunCoup" id="A0A1C7NHU6">
        <property type="interactions" value="100"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NHU6"/>
    <dbReference type="InParanoid" id="A0A1C7NHU6"/>
    <dbReference type="OrthoDB" id="2333384at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030674">
        <property type="term" value="F:protein-macromolecule adaptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031625">
        <property type="term" value="F:ubiquitin protein ligase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070086">
        <property type="term" value="P:ubiquitin-dependent endocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.640">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014752">
        <property type="entry name" value="Arrestin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011021">
        <property type="entry name" value="Arrestin-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011022">
        <property type="entry name" value="Arrestin_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050357">
        <property type="entry name" value="Arrestin_domain-protein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11188">
        <property type="entry name" value="ARRESTIN DOMAIN CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11188:SF17">
        <property type="entry name" value="FI21816P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02752">
        <property type="entry name" value="Arrestin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00339">
        <property type="entry name" value="Arrestin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01017">
        <property type="entry name" value="Arrestin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="E set domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Arrestin C-terminal-like" evidence="1">
        <location>
            <begin position="175"/>
            <end position="307"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM01017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ88560.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="362" mass="40966" checksum="38F8DA7F937017E0" modified="2016-11-30" version="1">MMMVHPLLVSNHADLQIVLEEDHVILYGTPEESAGVMLKGHVMLNCFGQTKVKSIKLKFTGIAQVSWTEVFDTKSKHKQHKAEHLIIEKEWTFIEFRKKVHCFQPGQYKWEFQLPLPGNLPISVKHTLGKIEYQFRAYCDRPAFSSNYMAHTLLTLNRMFFPLDLSDSVVISNTWAGKVNYDISIPSKWYSPNTIIPVAIDLEPIAYHLTVKSVCLTLKEYITGHVSGNHKTQGKKLRRIRDDQFVSSGDGHWIKTIFLPIPTELNFDMQSDLIQVKHKITLTIALANFDGHISELKAAIPVTIAPPMEEEGNILPAYQENCPSTLAHVSYSQLPSYSPPFISTDIRCGSDVLPTYESAITA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NI18</accession>
    <name>A0A1C7NI18_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Nuclear localization sequence-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">NSR1</name>
        <name evidence="6" type="ORF">A0J61_03312</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000140">
        <property type="protein sequence ID" value="OBZ88640.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NI18"/>
    <dbReference type="STRING" id="101091.A0A1C7NI18"/>
    <dbReference type="InParanoid" id="A0A1C7NI18"/>
    <dbReference type="OrthoDB" id="439808at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23236">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 4B/4H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23236:SF119">
        <property type="entry name" value="NUCLEAR RNA-BINDING PROTEIN SART-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 3" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="5">
        <location>
            <begin position="112"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="5">
        <location>
            <begin position="204"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="272"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="23"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="4">
        <location>
            <begin position="296"/>
            <end position="341"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OBZ88640.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="349" mass="37574" checksum="5820FCA2390B94C7" modified="2016-11-30" version="1">MGKSVAQTKAEKKIETESSSESSSEESSEEEEVEAKEEVGSESENESEDSNNEEESEDEEESNNEEESEDEEMEESGSSKRQRSDEEEEEERPKKVVKVEEVAKKAFGAEGCTVWVGQLSFDATTEQISEHFAQCGKVTAVRLRTDPNTGRSRGFAHIDFAKPSGKEAAMQLDGTEFMGRTIKVDNANAATPRGKDTNFGPKTKTVFVANLAHSLDEDGVRQAFEKFGTIVGDVRLPYNRETGKIRGIGYIEFESEDQAEAAVKGMNGVSIEGRPVRTDFSGDNDSERVSSRPARGGFGGSRGRGGRGGNRGGRGGFGGNRGGNRGGNRGGPRGGFGGNRGGRGRGGRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NI53</accession>
    <name>A0A1C7NI53_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Dynein heavy chain, cytoplasmic</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="14">Dynein heavy chain, cytosolic</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="18" type="primary">Dync1h1</name>
        <name evidence="18" type="ORF">A0J61_03137</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18 19">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="3">Consists of at least two heavy chains and a number of intermediate and light chains.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the dynein heavy chain family.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000130">
        <property type="protein sequence ID" value="OBZ88812.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="FunCoup" id="A0A1C7NI53">
        <property type="interactions" value="466"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NI53"/>
    <dbReference type="InParanoid" id="A0A1C7NI53"/>
    <dbReference type="OrthoDB" id="447173at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005858">
        <property type="term" value="C:axonemal dynein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045505">
        <property type="term" value="F:dynein intermediate chain binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051959">
        <property type="term" value="F:dynein light intermediate chain binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008569">
        <property type="term" value="F:minus-end-directed microtubule motor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048468">
        <property type="term" value="P:cell development"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003006">
        <property type="term" value="P:developmental process involved in reproduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007097">
        <property type="term" value="P:nuclear migration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072384">
        <property type="term" value="P:organelle transport along microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048731">
        <property type="term" value="P:system development"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd00009">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.920.20:FF:000002">
        <property type="entry name" value="Cytoplasmic dynein 1 heavy chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000122">
        <property type="entry name" value="Cytoplasmic dynein 1 heavy chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.1220:FF:000002">
        <property type="entry name" value="cytoplasmic dynein 1 heavy chain 1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.2620:FF:000001">
        <property type="entry name" value="Cytoplasmic dynein heavy chain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.472.130:FF:000002">
        <property type="entry name" value="Cytoplasmic dynein heavy chain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.710:FF:000005">
        <property type="entry name" value="Cytoplasmic dynein heavy chain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.140.100:FF:000002">
        <property type="entry name" value="Cytoplasmic dynein heavy chain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.58.1120:FF:000003">
        <property type="entry name" value="Cytoplasmic dynein heavy chain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.920.30:FF:000001">
        <property type="entry name" value="Cytoplasmic dynein heavy chain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.180.20:FF:000002">
        <property type="entry name" value="Cytoplasmic dynein heavy chain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000071">
        <property type="entry name" value="Cytoplasmic dynein heavy chain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000517">
        <property type="entry name" value="Cytoplasmic dynein heavy chain 1"/>
        <property type="match status" value="1"/>
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        <property type="entry name" value="Cytoplasmic dynein heavy chain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Dynein heavy chain, cytoplasmic"/>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
    <dbReference type="Gene3D" id="1.20.140.100">
        <property type="entry name" value="Dynein heavy chain, N-terminal domain 2"/>
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    </dbReference>
    <dbReference type="Gene3D" id="3.20.180.20">
        <property type="entry name" value="Dynein heavy chain, N-terminal domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.720">
        <property type="entry name" value="Region D6 of dynein motor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035699">
        <property type="entry name" value="AAA_6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035706">
        <property type="entry name" value="AAA_9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041658">
        <property type="entry name" value="AAA_lid_11"/>
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    <dbReference type="InterPro" id="IPR042219">
        <property type="entry name" value="AAA_lid_11_sf"/>
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    <dbReference type="InterPro" id="IPR026983">
        <property type="entry name" value="DHC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054354">
        <property type="entry name" value="DYNC2H1-like_lid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042222">
        <property type="entry name" value="Dynein_2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043157">
        <property type="entry name" value="Dynein_AAA1S"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041466">
        <property type="entry name" value="Dynein_AAA5_ext"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041228">
        <property type="entry name" value="Dynein_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043160">
        <property type="entry name" value="Dynein_C_barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024743">
        <property type="entry name" value="Dynein_HC_stalk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024317">
        <property type="entry name" value="Dynein_heavy_chain_D4_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004273">
        <property type="entry name" value="Dynein_heavy_D6_P-loop"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013602">
        <property type="entry name" value="Dynein_heavy_linker"/>
    </dbReference>
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        <property type="entry name" value="Dynein_heavy_tail"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042228">
        <property type="entry name" value="Dynein_linker_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46532:SF4">
        <property type="entry name" value="AAA+ ATPASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46532">
        <property type="entry name" value="MALE FERTILITY FACTOR KL5"/>
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    </dbReference>
    <dbReference type="Pfam" id="PF12774">
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="AAA_8"/>
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        <property type="entry name" value="DYN_lid"/>
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    </dbReference>
    <dbReference type="Pfam" id="PF17852">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18199">
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        <property type="match status" value="1"/>
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        <property type="entry name" value="Dynein_heavy"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="MT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="11 15" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="13" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="10" id="KW-0243">Dynein</keyword>
    <keyword evidence="6" id="KW-0493">Microtubule</keyword>
    <keyword evidence="12" id="KW-0505">Motor protein</keyword>
    <keyword evidence="8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0677">Repeat</keyword>
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        <location>
            <begin position="1964"/>
            <end position="2102"/>
        </location>
    </feature>
    <feature type="domain" description="AAA+ ATPase" evidence="17">
        <location>
            <begin position="2268"/>
            <end position="2448"/>
        </location>
    </feature>
    <feature type="domain" description="AAA+ ATPase" evidence="17">
        <location>
            <begin position="2647"/>
            <end position="2797"/>
        </location>
    </feature>
    <feature type="domain" description="AAA+ ATPase" evidence="17">
        <location>
            <begin position="2989"/>
            <end position="3155"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="2443"/>
            <end position="2464"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="15">
        <location>
            <begin position="3251"/>
            <end position="3321"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="15">
        <location>
            <begin position="3477"/>
            <end position="3518"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="15">
        <location>
            <begin position="3831"/>
            <end position="3858"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="16">
        <location>
            <begin position="2447"/>
            <end position="2458"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011655"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022197"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
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    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023175"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00033439"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="OBZ88812.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="4704" mass="539032" checksum="80D334256BEA623F" modified="2016-11-30" version="1">[encoded data, 4704 characters]</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-06-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NIA7</accession>
    <name>A0A1C7NIA7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_03422</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000147">
        <property type="protein sequence ID" value="OBZ88519.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NIA7"/>
    <dbReference type="InParanoid" id="A0A1C7NIA7"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ88519.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="72" mass="8225" checksum="B5F34F87635A98D6" modified="2016-11-30" version="1">MNRIDWSVEKLVIAIQNEALLSEEFHLAERDKTNLSRSYKSAILCPVIRAACDVFKVQIRSKHALLKVITTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NIB7</accession>
    <name>A0A1C7NIB7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Lanosterol 14-alpha demethylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">CYP51_0</name>
        <name evidence="9" type="ORF">A0J61_03108</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 6">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000128">
        <property type="protein sequence ID" value="OBZ88841.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NIB7"/>
    <dbReference type="FunCoup" id="A0A1C7NIB7">
        <property type="interactions" value="204"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NIB7"/>
    <dbReference type="InParanoid" id="A0A1C7NIB7"/>
    <dbReference type="OrthoDB" id="1055148at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd11042">
        <property type="entry name" value="CYP51-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050529">
        <property type="entry name" value="CYP450_sterol_14alpha_dmase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002403">
        <property type="entry name" value="Cyt_P450_E_grp-IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24304:SF2">
        <property type="entry name" value="24-HYDROXYCHOLESTEROL 7-ALPHA-HYDROXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24304">
        <property type="entry name" value="CYTOCHROME P450 FAMILY 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00465">
        <property type="entry name" value="EP450IV"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6 7" id="KW-0349">Heme</keyword>
    <keyword evidence="5 6 7" id="KW-0408">Iron</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 6 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="7" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0808">Transferase</keyword>
    <keyword evidence="8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="7"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="6">
        <location>
            <position position="455"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR602403-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OBZ88841.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="508" mass="57605" checksum="77B3FDB67C0F3E45" modified="2016-11-30" version="1">MAIISTLVHISLTELAIKAFIALGAYWIFHILSQLILPKDPKMAPVVFSWIPIFGNAIEFGKDPITFLKSSQAKYGDVFTFKLLNKNITACLGADGNQFVFNAKQNNASAAAAYNHMTKYVFGKDVCFDTAHSIFMEQKRFIKAGLNMETFRKDVPLILEECHMYFDRLGESGTIDAYKMFGQLIIYTASRALLGPEIRAALDDGVAQLYYDLDQGFRPINFMFPNLPLPAYRQRDRAREKLAEIYSKIIENRRSHPNEQHDDLLQTLMDSHYKDGSPIPNHQICGILTAALFGGQHTSSTVSSWAILELAHRPDILAALRQEMIDQLGSLKAEFTYDNLEKLELLENVVKETLRRHPPIFNMMRRVVTDRLVHDKTGLQIPKGNYLCAAPGVTQIDEAYFHDPLVWEPTRWSKKTDPVHQLEQGDDAHIDYGFGAVGISSRSPFLPFGAGRHRCIGEKFGYLQLKAIIGTFVKEFDFETISKTVPKPDYTSMVVVPENSTIRFTRRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NIC4</accession>
    <name>A0A1C7NIC4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Universal stress protein A family protein C25B2.10</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_03215</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000134">
        <property type="protein sequence ID" value="OBZ88740.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NIC4"/>
    <dbReference type="STRING" id="101091.A0A1C7NIC4"/>
    <dbReference type="InParanoid" id="A0A1C7NIC4"/>
    <dbReference type="OrthoDB" id="843225at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd23659">
        <property type="entry name" value="USP_At3g01520-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006015">
        <property type="entry name" value="Universal_stress_UspA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006016">
        <property type="entry name" value="UspA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47815">
        <property type="entry name" value="UNIVERSAL STRESS PROTEIN A FAMILY PROTEIN C25B2.10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47815:SF1">
        <property type="entry name" value="UNIVERSAL STRESS PROTEIN A FAMILY PROTEIN C25B2.10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00582">
        <property type="entry name" value="Usp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01438">
        <property type="entry name" value="UNVRSLSTRESS"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52402">
        <property type="entry name" value="Adenine nucleotide alpha hydrolases-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UspA" evidence="2">
        <location>
            <begin position="48"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="218"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="253"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="218"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="261"/>
            <end position="272"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00582"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ88740.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="272" mass="30273" checksum="3FB2B0713EA61A0A" modified="2016-11-30" version="1">MSKGIPIIQAENYVRGVSFDTMTDQDQPDYSFTLRGKTQGYQRTRRSRTFMVATDLAPYSDYALDWAIENIVDSGDEIIALSVLTVDMSENRPNLSAMLRNEELKAKERASTVMSKIMSAGGPEMKISAVIEFVIGKVQETIQNMISVYQPSMLIVGTRGMSELKGMFINSVSKYCLQHSPVPVVVVRPEDKVKKQLKKAAKKTNRLSGMFRISSHSSISSLNSKGSDSSDSSSEDEDTLRIEKKVQRLSVFDKIGRRSRSSSPARPLVAKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NJ65</accession>
    <name>A0A1C7NJ65_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Serine/threonine-protein kinase hal4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">hal4_4</name>
        <name evidence="10" type="ORF">A0J61_02780</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="7">Belongs to the protein kinase superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000109">
        <property type="protein sequence ID" value="OBZ89182.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NJ65"/>
    <dbReference type="FunCoup" id="A0A1C7NJ65">
        <property type="interactions" value="401"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NJ65"/>
    <dbReference type="InParanoid" id="A0A1C7NJ65"/>
    <dbReference type="OrthoDB" id="6513151at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd13994">
        <property type="entry name" value="STKc_HAL4_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050205">
        <property type="entry name" value="CDPK_Ser/Thr_kinases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24349">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 10" id="KW-0418">Kinase</keyword>
    <keyword evidence="3 6 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 7" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="9">
        <location>
            <begin position="114"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="55"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="17"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="70"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="83"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="150"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OBZ89182.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="410" mass="46845" checksum="7934FFC7A2C9A1D9" modified="2016-11-30" version="1">MVHLSNILHITHRSVGKSGSAQSSRRNSRDSSVASSATDGTTFEEGKNWFFKQLHSYQQQQQPSKRSTESSNSPLQLSPSPSRHTVQSDSNAPSSSAGTTKLHRMNTGSLRDYGECYKRLGKGSTAIISVCRSQKIQNSQAEPTKLYAIKQFRKRNKNETEKDYMKKLTSEFCISSTFCHTNVVETIDLVMDDQNRYCTVMEYCPGGDLFSAIMSEHMSEIEMACCFKQMMMGLAYLHSVGVAHRDIKPENLLLTLDGKLKITDFGVSDVFRCAWEKEGHKSHGLVGSEPYIAPEAFDKEEHYWGSKLDIWSAGIVMYSMWRGGHAWVRADKRVDREFCLYLRHWPTRGFPNFRKFPEPIRNLLYQLLDPNPDKRLTAEDVLQNKWVQSIQVCDRQHPHPHHLKKNIASN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NJ97</accession>
    <name>A0A1C7NJ97_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">poly(A)-specific ribonuclease</fullName>
            <ecNumber evidence="5">3.1.13.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="primary">Cnot7</name>
        <name evidence="18" type="ORF">A0J61_02706</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18 19">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Exonucleolytic cleavage of poly(A) to 5'-AMP.</text>
            <dbReference type="EC" id="3.1.13.4"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the CAF1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.13.4" evidence="5"/>
    <dbReference type="EMBL" id="LUGH01000106">
        <property type="protein sequence ID" value="OBZ89232.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NJ97"/>
    <dbReference type="FunCoup" id="A0A1C7NJ97">
        <property type="interactions" value="753"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NJ97"/>
    <dbReference type="InParanoid" id="A0A1C7NJ97"/>
    <dbReference type="OrthoDB" id="1164111at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030015">
        <property type="term" value="C:CCR4-NOT core complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004535">
        <property type="term" value="F:poly(A)-specific ribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000289">
        <property type="term" value="P:nuclear-transcribed mRNA poly(A) tail shortening"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006417">
        <property type="term" value="P:regulation of translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031047">
        <property type="term" value="P:regulatory ncRNA-mediated gene silencing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.10:FF:000005">
        <property type="entry name" value="CCR4-NOT transcription complex subunit 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039637">
        <property type="entry name" value="CNOT7/CNOT8/Pop2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006941">
        <property type="entry name" value="RNase_CAF1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10797">
        <property type="entry name" value="CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04857">
        <property type="entry name" value="CAF1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="11" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0540">Nuclease</keyword>
    <keyword evidence="17" id="KW-0539">Nucleus</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0678">Repressor</keyword>
    <keyword evidence="13" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="15" id="KW-0943">RNA-mediated gene silencing</keyword>
    <keyword evidence="16" id="KW-0804">Transcription</keyword>
    <keyword evidence="14" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="12" id="KW-0810">Translation regulation</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001663"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00008372"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022845"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="OBZ89232.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="305" mass="35073" checksum="7E150744D5216A30" modified="2016-11-30" version="1">MPINDTKFIKEVWAENLEEEMAYLRDLVEDYPYLAMDTEFPGVVARPIGTFKTSSDYHYQTLRCNVDLLKIIQLGVTFADQYGNLPGNICTWQFNFKFNLTDDMYAQDSIELLTKSGIDFKKHEEYGIDVEHFGELLISSGFVLLDDVKWISFHSGYDFGYLLKVLTCSLMPADETEFFELLRTYFPCIYDIKYLMKSCKNLKGGLQDIADDLQVARIGPQHQAGSDSLLTCTTFFKMRQMFFEDRIDDQKYLGYLYGLKCSPQHTHTTHHQALQALTTATSHLSITPTHEDTTAMNHTNKTNGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NJB6</accession>
    <name>A0A1C7NJB6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Meiosis protein mei2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">mei2</name>
        <name evidence="4" type="ORF">A0J61_03053</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000125">
        <property type="protein sequence ID" value="OBZ88899.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NJB6"/>
    <dbReference type="STRING" id="101091.A0A1C7NJB6"/>
    <dbReference type="InParanoid" id="A0A1C7NJB6"/>
    <dbReference type="OrthoDB" id="417481at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007201">
        <property type="entry name" value="Mei2-like_Rrm_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23189">
        <property type="entry name" value="RNA RECOGNITION MOTIF-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04059">
        <property type="entry name" value="RRM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="Mei2-like C-terminal RNA recognition motif" evidence="3">
        <location>
            <begin position="286"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="401"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="415"/>
            <end position="425"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF04059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OBZ88899.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="425" mass="49769" checksum="B07D33E4BE6B5039" modified="2016-11-30" version="1">MAFIQSESVICPSWDLPNHCPVLLSNSDKDQSIPLIKSKLPTRHLLIYATDNSHHSTMTLVSTELDKPHLIRCVYPYLYSGMTIVSYYSLQEAQLALERFRKQDHSFHLEYAKPCLVNKRCNERVFVTVRQLQGLDIKQHHYRHHLQQMGTIDSLSETWISPYCVLINLEYDDERIHEQLYQQYHQMILEGCYWSVYFAENNDFTCYCDQWKDVPIKKEESYFTHDLNLTKSSTTLSSFLSCSSSSTTTTTTSTSHRSMIESKKKKVDVMLNETHLENIRKGLDTRTTYMIRNIPNKYTQKMLMDSINATHANTYDFLYLRIDFQNKCNVGYAFINFTDPKSVISFAQERIDKKWDHFNSDKRCALSFATIQGKTALIKKFKNSQVMSEDVAYQPKLFYSSGPNKGKEQPFPMNSHHRERKHQRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NJS0</accession>
    <name>A0A1C7NJS0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_02705</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000106">
        <property type="protein sequence ID" value="OBZ89238.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NJS0"/>
    <dbReference type="InParanoid" id="A0A1C7NJS0"/>
    <dbReference type="OrthoDB" id="2284923at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="64"/>
            <end position="84"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ89238.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="104" mass="11922" checksum="E6B7A7BAF87BD3D5" modified="2016-11-30" version="1">MTACLCSYVVNCGILASLSFFNRMLSTSLPLPIHSLSPDTELCAHFRRYWQDQFKRQMAKQASLGRSVLLHACCLYTFILYLPMKTTARSRLVCWRLGLFAKPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NK40</accession>
    <name>A0A1C7NK40_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Protein RTM1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">RTM1_0</name>
        <name evidence="6" type="ORF">A0J61_02549</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000097">
        <property type="protein sequence ID" value="OBZ89415.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NK40"/>
    <dbReference type="FunCoup" id="A0A1C7NK40">
        <property type="interactions" value="36"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NK40"/>
    <dbReference type="InParanoid" id="A0A1C7NK40"/>
    <dbReference type="OrthoDB" id="3358017at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007568">
        <property type="entry name" value="RTA1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31465">
        <property type="entry name" value="PROTEIN RTA1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31465:SF1">
        <property type="entry name" value="PROTEIN RTA1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04479">
        <property type="entry name" value="RTA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="20"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="52"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="82"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="122"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="159"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="201"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="238"/>
            <end position="262"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OBZ89415.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="278" mass="31585" checksum="1FDD01B707B17CC0" modified="2016-11-30" version="1">MIPSLYNTGASQALFFFHYIPNLPLAIVSLCVYAIFTIYLTLRISLSKSANYLYILAFTGLMETIGYAIRIACHYFTDLGRYIGMTLFLLLAPNALALVNYKTVGEIIRLSGVQTNRFYLKHSFVTWFFFASDIFAFALQGAGGGMQTSTDLYQTGRVITLIGLALQLVFFACYGCITIYVHRSPEYQYHVAHQPNAKRRLIFCLYVTIILLYIRSIYRVAEYASGYDGVIATTEWAFYVFDTLVIAASFAVYSVFFIGQYLPKRDQAIESRTDLEKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NKG1</accession>
    <name>A0A1C7NKG1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Putative glutamate 5-kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">A0J61_02460</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000093">
        <property type="protein sequence ID" value="OBZ89498.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NKG1"/>
    <dbReference type="FunCoup" id="A0A1C7NKG1">
        <property type="interactions" value="283"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NKG1"/>
    <dbReference type="InParanoid" id="A0A1C7NKG1"/>
    <dbReference type="OrthoDB" id="409889at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004349">
        <property type="term" value="F:glutamate 5-kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901607">
        <property type="term" value="P:alpha-amino acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd04242">
        <property type="entry name" value="AAK_G5K_ProB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd21157">
        <property type="entry name" value="PUA_G5K"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.1160.10:FF:000018">
        <property type="entry name" value="Glutamate 5-kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1160.10">
        <property type="entry name" value="Acetylglutamate kinase-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.130.10">
        <property type="entry name" value="PUA domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00456">
        <property type="entry name" value="ProB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036393">
        <property type="entry name" value="AceGlu_kinase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001048">
        <property type="entry name" value="Asp/Glu/Uridylate_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041739">
        <property type="entry name" value="G5K_ProB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001057">
        <property type="entry name" value="Glu/AcGlu_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011529">
        <property type="entry name" value="Glu_5kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005715">
        <property type="entry name" value="Glu_5kinase/COase_Synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019797">
        <property type="entry name" value="Glutamate_5-kinase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015947">
        <property type="entry name" value="PUA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036974">
        <property type="entry name" value="PUA_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01027">
        <property type="entry name" value="proB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43654">
        <property type="entry name" value="GLUTAMATE 5-KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43654:SF3">
        <property type="entry name" value="GLUTAMATE 5-KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00696">
        <property type="entry name" value="AA_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000729">
        <property type="entry name" value="GK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00474">
        <property type="entry name" value="GLU5KINASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53633">
        <property type="entry name" value="Carbamate kinase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88697">
        <property type="entry name" value="PUA domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00902">
        <property type="entry name" value="GLUTAMATE_5_KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50890">
        <property type="entry name" value="PUA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 9" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3" id="KW-0641">Proline biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aspartate/glutamate/uridylate kinase" evidence="8">
        <location>
            <begin position="30"/>
            <end position="259"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022650"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00696"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OBZ89498.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="409" mass="44597" checksum="8CD857EF951E99CC" modified="2016-11-30" version="1">MHYFQSEDEVAMGIYRNILNTHRTSKASLTLVIKVGTSSICDEVTHYPLLGNLSRIVETIIRLKRLGHRVVLVTSAAVGTGLRRLNMGEKPSKLAAIQAIAAVGQGRLMSMYDDLFGQFEQPVAQILLTRNDLADRAQYLNAVNCLEELLDMGVVPIVNENDSISVQEIKFGDNDTLSAITAGMVKADYLFLMTDVDCLYTDNPRSNPDAHPVLVCEDIDLLRDQVKVSAPGSALGTGGMITKLVAADLATAAGVTTVITRGATPENIMPIIEGATQNVPLHTRFVAKPQPLMDRKWWILHGLHTAGTVYVESEVSKSIHDGEADKDLFAHSISHVEGTFVEHQAVRLVVQHKDSHGLIDNITIAKGIVNYSSAEIMRIMLAGKQNLNDSLGYKNGNCIISRDNMAIST</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NL02</accession>
    <name>A0A1C7NL02_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_02461</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000093">
        <property type="protein sequence ID" value="OBZ89499.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NL02"/>
    <dbReference type="STRING" id="101091.A0A1C7NL02"/>
    <dbReference type="InParanoid" id="A0A1C7NL02"/>
    <dbReference type="OrthoDB" id="2555519at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="136"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="162"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="386"/>
            <end position="503"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="259"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="143"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="172"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="386"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="426"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="464"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="492"/>
            <end position="503"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ89499.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="503" mass="55892" checksum="AF5DE35D4A9B47BE" modified="2016-11-30" version="1">MRTTKERKGEVTMLTKELTPNAKAVNIIRPINQRTQQRSDDAHLFHHQQSNNRTFSTSADSTFPRVNTLYSNTVLTSSPMIRQPSAESNPGLSFFCQSPTSNNHNVITKNQQSKNTPQVETVQPLVISRISLSNFNQNRRSLSPPPPPPPPLNIRRRVISTADNDGITALDDYNDDDDEEEEEEEEEEDLIDQLDDIEENDSEDKTTSLPPPQQLRRTPSSYNPLFGMMGGGLGSFLLRGPMATQAKTQADEARVHRKIEDLEIEKKSLMTLNQTLETVVKEQSDTISNLQNKLAAIERPLTPGLDTNLSKNGIMSPSMTGLGIMDSAELEKCLQDEDAAFERIRTVLVDLIDQAQAAIAENERKSQGYEVIAHVKGNIASSNTLRRSSSLYNSRPKSVVGTSSRNSTVGISSQQKNRVTRRISLGNLNQQVDTSNDTRRLSSPSKQSPATSPIPNRRYSMQRSVSRTSSVVSVGSPQPTVTRASKYKNKSSDSQTTARKWLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NLB3</accession>
    <name>A0A1C7NLB3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_02077</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000074">
        <property type="protein sequence ID" value="OBZ89865.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NLB3"/>
    <dbReference type="STRING" id="101091.A0A1C7NLB3"/>
    <dbReference type="InParanoid" id="A0A1C7NLB3"/>
    <dbReference type="OrthoDB" id="4590138at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39474:SF1">
        <property type="entry name" value="FUNGAL SPECIFIC TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39474">
        <property type="entry name" value="UNNAMED PRODUCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ89865.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="89" mass="10380" checksum="F0E63E677BC4EF6D" modified="2016-11-30" version="1">MSSTDTKKPLLALPSTAEETVKVDMNDTYKLKELGPVVINEDGTMSRINNWHEMNEIERGNVNRILLKRNRDRLAKLKEQLQQKEEEKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NLL3</accession>
    <name>A0A1C7NLL3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein C11G11.07</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_01887</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000065">
        <property type="protein sequence ID" value="OBZ90071.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NLL3"/>
    <dbReference type="FunCoup" id="A0A1C7NLL3">
        <property type="interactions" value="1078"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NLL3"/>
    <dbReference type="InParanoid" id="A0A1C7NLL3"/>
    <dbReference type="OrthoDB" id="435593at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031267">
        <property type="term" value="F:small GTPase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006606">
        <property type="term" value="P:protein import into nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013598">
        <property type="entry name" value="Exportin-1/Importin-b-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001494">
        <property type="entry name" value="Importin-beta_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051345">
        <property type="entry name" value="Importin_beta-like_NTR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057941">
        <property type="entry name" value="TPR_TNPO3_IPO13_2nd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057942">
        <property type="entry name" value="TPR_TNPO3_IPO13_3rd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058537">
        <property type="entry name" value="TPR_TNPO3_IPO13_4th"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12363:SF53">
        <property type="entry name" value="MRNA TRANSPORT REGULATOR MTR10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12363">
        <property type="entry name" value="TRANSPORTIN 3 AND IMPORTIN 13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03810">
        <property type="entry name" value="IBN_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24138">
        <property type="entry name" value="TPR_TNPO3_IPO13_2nd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24140">
        <property type="entry name" value="TPR_TNPO3_IPO13_3rd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24139">
        <property type="entry name" value="TPR_TNPO3_IPO13_4th"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08389">
        <property type="entry name" value="Xpo1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00913">
        <property type="entry name" value="IBN_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50166">
        <property type="entry name" value="IMPORTIN_B_NT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Importin N-terminal" evidence="1">
        <location>
            <begin position="28"/>
            <end position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50166"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ90071.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="919" mass="105177" checksum="3450E67C625D80C5" modified="2016-11-30" version="1">MATESTTRVLEALSSLYNSTDKQTNREANRWLESFQKKPEAWAVADYLLKSNDVNLETQLFAAQTLKQKITYDLRELDSKARLQLRDGLIERLGQLGDTSKAVMVQLCLAIAILAIQLLEWESVINDLVEKFSHSHKGLVCLLEILKLLPEEMNQNARRLPLTDTEYRTRAEKLIDNNAPHILNLLSVYMQSSGSDSDLQVRIFQCLSSWIRTGEMDIRMLSASPLIQLAFKGLESESLFEVSVDVVSEIIYETRDIDACQDIIQQIYPCFHPMLIKLTEATKEDADEDEEIVRGYCRIFCEAGEAYINLICRHPDAFKILLEGILKCTAYHDLDIVPMTFKFWYELTLALQTETYAQAIPLLAPYYDRLVDVMIGHLKYPVDAMTAEERDEFRDFRHKMGDTLKDCCRILTPQRCLVKPMQLLTGLLNSAEASWQQIEAPIFALRVMGSEVPQDENEVMPHIMEFLSQLPDHPKIRYAATLVISRYSFWTELHPQYITYQLNFISSGFQNDEVAAASALALKNLCKDCSEHLVDYVPQLQAFYMNVAKSLPFRDVLEVTEAVSHVITVISPSEIQNALQLFCLPVAQELHGLVSKEKESLSQEDYVKIGDLLEQINVFFDIIRPEIPLGQPHPCVTFISELWPVLDTTLTRFGGLDTVSEPLCKCFNSFMLSYGPHFIPFLPQLMERIVNAFNLTCHSCYLWVALKLVRAFARDEGQRPCFEFVQQLSQVLFVKLQTQQVNTMPDVIEEYFRLTMAFLEHAPLLILNEPSLFSTLFQANLASLSINESHALEAVLKFNYRLLKMTDKSSSILTLYREYGADLTLVLCNGVLDYYSQDLIPDVASIFQLLAETLPSESAQWIMRAINEVPEDYLSADLKSEFMSNWTSAITGQHWVKIRRILSDFAATYRRRNASKDRH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NLP0</accession>
    <name>A0A1C7NLP0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Acidic endochitinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">CHIA_0</name>
        <name evidence="4" type="ORF">A0J61_02194</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000079">
        <property type="protein sequence ID" value="OBZ89769.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NLP0"/>
    <dbReference type="InParanoid" id="A0A1C7NLP0"/>
    <dbReference type="OrthoDB" id="6020543at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004568">
        <property type="term" value="F:chitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001223">
        <property type="entry name" value="Glyco_hydro18_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050542">
        <property type="entry name" value="Glycosyl_Hydrlase18_Chitinase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45708">
        <property type="entry name" value="ENDOCHITINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45708:SF49">
        <property type="entry name" value="ENDOCHITINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00704">
        <property type="entry name" value="Glyco_hydro_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51910">
        <property type="entry name" value="GH18_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GH18" evidence="3">
        <location>
            <begin position="6"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OBZ89769.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="424" mass="47164" checksum="7799CBE1458C04B2" modified="2016-11-30" version="1" fragment="single">ILRRKDGLALYWGQGDYNEKRLSYYCDQEGVSIVILSFIANFSGGPKKSPVLDLSDNCKNTNNCSEAARDIKHCQKKGIKVLISLGGAVGPYKRQSWDPDLLAWWLWTKFLGGDDESVSRPFGDVVLDGVDYDPEGVDGEGYDRNIDTLRKLFKTQYPRREYLITAAPQCPDLEKYEKNAVYNILNPSNPKYNSYPNITFVQFYNNKCSASAYNSNKPTAFNFSAWNKWAQKTGSKIYLGVLGKQNNMDTGYVNYEKLTVILDDVERSKNFGGVMMWDASYAYNNPVPYLDGMQFGQAVARYLKQLATSGSSRLAAAFSGITSAFSEFRLPILVPIGGDDIGLLPFPCQGQPFLSLRSVTSESLAKSFGAPVDEITSHLTELGVSGDQYVNPGSYICITPHPGYNGSFVISYLYNSTINEEEST</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NM02</accession>
    <name>A0A1C7NM02_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="8">40S ribosomal protein S10-B</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">rps10b_0</name>
        <name evidence="8" type="ORF">A0J61_03642</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the eukaryotic ribosomal protein eS10 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000161">
        <property type="protein sequence ID" value="OBZ88304.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NM02"/>
    <dbReference type="STRING" id="101091.A0A1C7NM02"/>
    <dbReference type="InParanoid" id="A0A1C7NM02"/>
    <dbReference type="OrthoDB" id="5211809at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022627">
        <property type="term" value="C:cytosolic small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005326">
        <property type="entry name" value="Plectin_eS10_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037447">
        <property type="entry name" value="Ribosomal_eS10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12146">
        <property type="entry name" value="40S RIBOSOMAL PROTEIN S10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12146:SF0">
        <property type="entry name" value="RIBOSOMAL PROTEIN S10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03501">
        <property type="entry name" value="S10_plectin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4 8" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Plectin/eS10 N-terminal" evidence="7">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="25"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="41"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF03501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OBZ88304.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="79" mass="8827" checksum="C04BDDF15FBA719D" modified="2016-11-30" version="1" fragment="single">TLTDEGIDYLREYLHLPQEIVPATLKKSARPAAPRRAFGGEGRENRGPRGDRGDYRRKEGASGDFKPEFRGGLGRGNRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NMN8</accession>
    <name>A0A1C7NMN8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">MFS-type drug efflux transporter P55</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">A0J61_01606</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000053">
        <property type="protein sequence ID" value="OBZ90347.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NMN8"/>
    <dbReference type="STRING" id="101091.A0A1C7NMN8"/>
    <dbReference type="InParanoid" id="A0A1C7NMN8"/>
    <dbReference type="OrthoDB" id="10021397at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd17502">
        <property type="entry name" value="MFS_Azr1_MDR_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1720.10">
        <property type="entry name" value="Multidrug resistance protein D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501:SF191">
        <property type="entry name" value="VACUOLAR BASIC AMINO ACID TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00216">
        <property type="entry name" value="SUGAR_TRANSPORT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00217">
        <property type="entry name" value="SUGAR_TRANSPORT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="52"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="92"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="123"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="147"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="181"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="213"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="251"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="282"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="315"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="358"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="384"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="415"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="452"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="518"/>
            <end position="539"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="8">
        <location>
            <begin position="58"/>
            <end position="545"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00044273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OBZ90347.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="565" mass="61915" checksum="DAF702F9F2A72FA8" modified="2016-11-30" version="1">MKEEQMNRTIGEISETDIGRSSSTLDARDQISILDEKEVIEDNRNFKSTKELINFTITIIGIIIAMFMMSLNSTVVAPAMSTIATQLNGVQSQTWIATAYLVALNAFQPLSGKFSDIFGRKPVYLFGIIFFFIGSLINGLSTNINMLIAGRVIQGFGGGGVMSMTYIIISEVSPPALRPRFQSMLSVVYGIASVVGPLIGGGFVDHADWHWDFWLNVILAAVSLVIIFFYLNETRQATESSFVDKLKRIDWLGSLFAIGFIVCLLLAMNWGSSYGWSSAHSIGPFVAAGVALVLLIITEGWIAKEPLMPFSVLSNPACIVVYVYMITLGLTFIGTLYFGPIFYQAVFDANSTTSGLRLIPFMVCLIVGSVGCGFILRLLPRTKFYLILGSACNLIGYGLFFTVKENSSWGQQAGYLAFSGFAFGISQQNCILSVQSAVEKKDIAVATSLNNFFMMLACSVGVVIYQALYQVFLKAQFSKLPADVFAAANQHGALKNYLYIKDLPIDVKVPVVHAYYNALHILFILPIVAAAIGFIFTLFCKDVRYGAPTVPQKKDEEAATLQEKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NP51</accession>
    <name>A0A1C7NP51_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">BP74 N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_01161</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000034">
        <property type="protein sequence ID" value="OBZ90788.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NP51"/>
    <dbReference type="InParanoid" id="A0A1C7NP51"/>
    <dbReference type="OrthoDB" id="2232403at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056422">
        <property type="entry name" value="BP74_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053344">
        <property type="entry name" value="cAMP-inducible_BP74-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35883:SF1">
        <property type="entry name" value="CALMODULIN-BINDING PROTEIN CAM-BP15-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35883">
        <property type="entry name" value="CYCLIC AMP-INDUCIBLE PROTEIN BP74-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23621">
        <property type="entry name" value="BP74_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BP74 N-terminal" evidence="1">
        <location>
            <begin position="9"/>
            <end position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF23621"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ90788.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="142" mass="16294" checksum="E34ADC773FD00FB1" modified="2016-11-30" version="1">MFWTIHAEEVAFRFKNNAVTFVVKLSDPKTIEHARDLVYERTTNYPHIQGNIVKKADPMNIPWTFTLDPDSVSFFNGKDSRNGNSTACDIGIRWAEYYLDDVCNYILPDCFWCPTNSTLIEEIKTDLNMPTPPPKKSGNTAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NP64</accession>
    <name>A0A1C7NP64_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">NUA/TPR/MLP1-2-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">A0J61_01025</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000028">
        <property type="protein sequence ID" value="OBZ90921.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="FunCoup" id="A0A1C7NP64">
        <property type="interactions" value="704"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NP64"/>
    <dbReference type="InParanoid" id="A0A1C7NP64"/>
    <dbReference type="OrthoDB" id="343070at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005643">
        <property type="term" value="C:nuclear pore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017056">
        <property type="term" value="F:structural constituent of nuclear pore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006406">
        <property type="term" value="P:mRNA export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.2610">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.1700">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057974">
        <property type="entry name" value="NUA/TPR/MLP1-2-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18898:SF2">
        <property type="entry name" value="NUCLEOPROTEIN TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18898">
        <property type="entry name" value="NUCLEOPROTEIN TPR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25785">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NUA/TPR/MLP1-2-like" evidence="6">
        <location>
            <begin position="417"/>
            <end position="509"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1313"/>
            <end position="1333"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1376"/>
            <end position="1416"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1463"/>
            <end position="1485"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1589"/>
            <end position="1619"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1669"/>
            <end position="1783"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="17"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="150"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="263"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="379"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="486"/>
            <end position="566"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="602"/>
            <end position="699"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="760"/>
            <end position="1080"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="1107"/>
            <end position="1215"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="1313"/>
            <end position="1322"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="1393"/>
            <end position="1416"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="1669"/>
            <end position="1678"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF25785"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OBZ90921.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="1783" mass="201788" checksum="436F0FCF110B2316" modified="2016-11-30" version="1">MATSSEEAALLKQSLTENELQQKNHQLQTTLQELSERNLSLPLKIMLTENELEVVRLEKEKLQSTTLTIENEKKETEQKLVQLTDSERLLREYIKTTVDTLNSKRDALQKTQAELNELRQKEITNRIEIERATFQIRQLQTSTQSIEHQLLTANARVESLNNQIRALENERDNLREDMRLERSRLEEKLDDLKAEKESSSDQIEQLHSQLEHARDRVLQAEDKLADMKAARDQLELSLGSTSQAFKKLQKIHEEYSVDSHKRMAAYEAKVALISKEKEDLDRAKKELEQQLFDERELRKAQFNQITGFHAANDDDDSKPPSDLLKLIHEYQQIGKRPEDIFQDYFDLRSKYMQSIQKNAHESDCVESLSRKLNEKAKLFDRVHRELKSAKAANIDLEQKIQQEKTQRQQAEASRQLMTHQMDDLKKENNSLKASLNDTTYQLQFILSDIERRNQPIPAALKSTATLLNGTEITPSLPHNQLVYTNVAELQDCNKQLMIENKTLKDKVQQLSDEAGTSDLIRRSDTSFYKAAVEEAKQAMSELEAKNQELQTKLDRKNAECDNYQKIINQFGDSDDVSAKFAQIQETQNRQREEMDVTFDQYRRETLVEVNKLKEELESVRNSDREARLSLSEVSSQRRYLEQRVERLNASTEELNQELKSAHRQSDTLHERITARDKEIAEIKSELQDYKARVENLRYENTLLTTRMEIANNAYKDVKEAVTKESSEKAQLTSLLEVIKSRMDDVIASGREKTEQSVEIVERLTRELRHARESLTLAEKQLESYKAVDQNEMQDKYKEATIEIRLLKTKIAELEQQLSNVNQERIIAQTKLSSAEEQLKAANSNANTNDESSDVNAHLLAEAQDRVRVLEANIEEFHTIIRESETKTKELQEKHENYIVECQATIDKLIKNLEERTTEVTNIQNEAQMAIAEYKSLSEQSKAAQEELNIQKQALEEKVGSLELSNTEQQEKIKTLEATLEEKTSIHKEVETKLANETHIAEEQRQTINSLRADVSNLTFEISQYKTTIAAASNTESSLRAELERELSERNSSEQEWKKKLDEAEKRREQLSESVSELIAKHAEWSVAQDKENGSERAEFDRTAKEIIEQLREACATLHIEKDASENNYRHERLKVKRAESEAEAARSQVALLQADLTRLRQENKELSEKELKASSTTQLERDAFKAQNHQLLYENNVLRELREAAQLEKSQLADQVAPLKLKISILESQLETTTQSLEVLTKGQKDWAARSAKLLEKYNKSDPAETESLKAELETTKSELEKTKTELESVKTEVEKLQAENKKLESTVETLEETVKTKESERANVTMKANERGRIAMDLKRRLEASEKSLNEAKEKLAQAEKKTAEAEKKIADVATANGAANAEPEISPTQKAELEKLTKEKETLEEQKKAAEEAKTTLEAELATAKTETANFEKKYSGLLQKARHVQIEKNRIAKELEALKAAAATSTSTTSTNDDSGSTNNNTETIALKSKIAELEKELAAARKSLSESTVEINRYKAQTSMAQNKSNRLQKELDALKASAASAASAASAEKKNLKTPLEDVTLQAAAPLPAPTLVESAPVTLKATAVPPVEEKDSAPLTEEVAPVPAASDLAETEELPTTPVAIASTSEPSNKDNTIIEAELNMEMDADVAADENVSETVVVETPPNNTVTVETPAPTDELVEEKNEEVPVEVEESSEATKGNAEQKLSTVATDVEPSTVDSPIILNEEVGEAASLDTNNNEDDPSETKSSGVKRDRGESEEEGEINEPGSPKKKANTSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NPK4</accession>
    <name>A0A1C7NPK4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Pumilio homology domain family member 3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">PUM2_0</name>
        <name evidence="11" type="ORF">A0J61_00997</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the PUF3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000027">
        <property type="protein sequence ID" value="OBZ90948.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NPK4"/>
    <dbReference type="STRING" id="101091.A0A1C7NPK4"/>
    <dbReference type="InParanoid" id="A0A1C7NPK4"/>
    <dbReference type="OrthoDB" id="668540at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003730">
        <property type="term" value="F:mRNA 3'-UTR binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000288">
        <property type="term" value="P:nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07920">
        <property type="entry name" value="Pumilio"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.10.10:FF:000004">
        <property type="entry name" value="Pumilio homolog 1 isoform 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033133">
        <property type="entry name" value="PUM-HD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033712">
        <property type="entry name" value="Pumilio_RNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001313">
        <property type="entry name" value="Pumilio_RNA-bd_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12537:SF12">
        <property type="entry name" value="MATERNAL PROTEIN PUMILIO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12537">
        <property type="entry name" value="RNA BINDING PROTEIN PUMILIO-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00806">
        <property type="entry name" value="PUF"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="SMART" id="SM00025">
        <property type="entry name" value="Pumilio"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50302">
        <property type="entry name" value="PUM"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50303">
        <property type="entry name" value="PUM_HD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="PUM-HD" evidence="10">
        <location>
            <begin position="438"/>
            <end position="778"/>
        </location>
    </feature>
    <feature type="repeat" description="Pumilio" evidence="7">
        <location>
            <begin position="458"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="repeat" description="Pumilio" evidence="7">
        <location>
            <begin position="494"/>
            <end position="529"/>
        </location>
    </feature>
    <feature type="repeat" description="Pumilio" evidence="7">
        <location>
            <begin position="530"/>
            <end position="565"/>
        </location>
    </feature>
    <feature type="repeat" description="Pumilio" evidence="7">
        <location>
            <begin position="566"/>
            <end position="601"/>
        </location>
    </feature>
    <feature type="repeat" description="Pumilio" evidence="7">
        <location>
            <begin position="602"/>
            <end position="637"/>
        </location>
    </feature>
    <feature type="repeat" description="Pumilio" evidence="7">
        <location>
            <begin position="638"/>
            <end position="673"/>
        </location>
    </feature>
    <feature type="repeat" description="Pumilio" evidence="7">
        <location>
            <begin position="674"/>
            <end position="709"/>
        </location>
    </feature>
    <feature type="repeat" description="Pumilio" evidence="7">
        <location>
            <begin position="710"/>
            <end position="752"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="47"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="182"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="359"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="331"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="17"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="77"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="182"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="364"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="9">
        <location>
            <begin position="379"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="394"/>
            <end position="404"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00060736"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00081811"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="OBZ90948.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="804" mass="90326" checksum="7FAF460DBE221ED0" modified="2016-11-30" version="1">MPTLVNDTAKSGGLKQPQVSNSPKGQQLSALLQPEYDYDLFNHSGASSFFPDEEVDRSSSAPPIQGLQRSRDLKLSNPANVSAGPSSATVNTAVPGNSSYDSLQTWKLWKGGNSDNFGNQMEGNDPKAKLVDIIQQDFPRTPSPMFGFQQGLRDDNAEYDARAYGYNNHLLQQPSGSRINALRSSQFSPTRSNSTPPVNNRPLHRQASPTPYGATPEEDMLMKPFSNLGLADEDDYLRYHQQYPLRQQQQQQLQSPYPYYDIGHMPLSSSALDLAGNEEYEAIYGKWSSEDAAAYHMRSKQGPLTAPIPYDPAGFPMSDTSTDKKLRQLQIQQQQLLIRQQQQQLAVARQQLLIQQQQQQQQQHAFNPSNNTSNHHSRGGNGRVTAGNGGNGNMVGVAVMSGMNEIGHGSGNGHSGNTSRVQETVSRSSSSQDLTLSMRSALLEEFRNCKNKKYELKDIAGHIVEFSGDQHGSRFIQQKLETANSEEKQMVFEEVLPNALQLMTDVFGNYVLQKFFEHGNQMQKSILAKQMEGHVLSLSLQMYGCRVVQKALEHVLTEQQATLVDELDGCVLKCIKDQNGNHVIQKAIERVPAQHIQFIIDAFHGQVYNLATHPYGCRVIQRMFEHCTETQTGPLLDELHRCTSQLVQDQYGNYVIQHILERGRPEDKAKIVEKILGQILPLSKHKFASNVVEKCVDYGSKRDRQLLIEEVVQNRPDGTYPLVTMMKDQYANYVVQKMLDVVDEDQREILVTKIRPHLQSLKKYTYGKHLIQKVEKLGITYDSGHLAEESHGEKQENTREDVDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NPK5</accession>
    <name>A0A1C7NPK5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">60S ribosomal protein L7-B</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">rpl7b_0</name>
        <name evidence="6" type="ORF">A0J61_00912</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uL30 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000024">
        <property type="protein sequence ID" value="OBZ91047.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NPK5"/>
    <dbReference type="FunCoup" id="A0A1C7NPK5">
        <property type="interactions" value="539"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NPK5"/>
    <dbReference type="InParanoid" id="A0A1C7NPK5"/>
    <dbReference type="OrthoDB" id="28644at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022625">
        <property type="term" value="C:cytosolic large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000463">
        <property type="term" value="P:maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01657">
        <property type="entry name" value="Ribosomal_L7_archeal_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1390.20:FF:000003">
        <property type="entry name" value="60S ribosomal protein L7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1390.20">
        <property type="entry name" value="Ribosomal protein L30, ferredoxin-like fold domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036919">
        <property type="entry name" value="Ribo_uL30_ferredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039699">
        <property type="entry name" value="Ribosomal_uL30"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018038">
        <property type="entry name" value="Ribosomal_uL30_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005998">
        <property type="entry name" value="Ribosomal_uL30_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035808">
        <property type="entry name" value="Ribosomal_uL30_euk_arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016082">
        <property type="entry name" value="Ribosomal_uL30_ferredoxin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012988">
        <property type="entry name" value="Ribosomal_uL30_N_euk"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01310">
        <property type="entry name" value="uL30_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11524">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11524:SF16">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN UL30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00327">
        <property type="entry name" value="Ribosomal_L30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08079">
        <property type="entry name" value="Ribosomal_L30_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55129">
        <property type="entry name" value="Ribosomal protein L30p/L7e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00634">
        <property type="entry name" value="RIBOSOMAL_L30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 6" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Large ribosomal subunit protein uL30 N-terminal eukaryotes" evidence="5">
        <location>
            <begin position="20"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="domain" description="Large ribosomal subunit protein uL30-like ferredoxin-like fold" evidence="4">
        <location>
            <begin position="96"/>
            <end position="146"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007594"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00327"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF08079"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OBZ91047.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="255" mass="29275" checksum="AA8BDB9871CF20A1" modified="2016-11-30" version="1">MTYSFIFLNSNVPAANDVLVPETLLKKRKSDADAAAKASAQKAEARKAKIAKRRDIFKRAAKYHAEYKANSLNEIRLRRQAKAQGNYYVPAQEKLVFVVRVRGINNIAPKPRKVLQLLRLLQINNGVFVRLNKATSEMLQLIQPYVAYGYPNLKTIRELIYKRGYGKVNKQRIPIHDNAVIEQALGKYNIICVEDLIHEIATVGPHFKEASNFLWPFKLSNPNNMWRERKLLNFIEGGDTGNREHFINKLVQSMN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NPT5</accession>
    <name>A0A1C7NPT5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_01039</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000029">
        <property type="protein sequence ID" value="OBZ90919.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NPT5"/>
    <dbReference type="STRING" id="101091.A0A1C7NPT5"/>
    <dbReference type="InParanoid" id="A0A1C7NPT5"/>
    <dbReference type="OrthoDB" id="2281294at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="254"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="309"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="287"/>
            <end position="297"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ90919.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="478" mass="54272" checksum="C084CEDC399AA925" modified="2016-11-30" version="1">MLSAVQHNLPSTEFKSNNKIGVLTRKKAIENFRCSKEDITELITEDAAIDEDLQLADRVFCATIHKFTKQNCPDPSLNKKRSTRYSFLENWFLHKIYSKSQQTLLGVYPVKPAVILSGDDFMFTPPFLQSPPPQPFEDIDDEEYYYDEDEHWETNEYLYSLSPCPESKQAADNDSMFYRHQDEGEEDCENNKLKMLSTAFLKSPSLLESPPCFYNQDDIYNFVAENIQLEEEDIFLEDDRIRALNDIRSFAIDTQQTRHEDEDEDEDDSLSGLSDPTTNDSDEPDLSYSSTTITSGSYEEERQDMLNDDEVSGSYHSTTGNIVIPINNKTNEDDVSQITQVSPVTRSSTFLSQRSSLDDDSSVHSYQSLADIINSQQMSQDISISSIPSRIYHYGSVKSQALGSKMKSFVNNLSGHHANNDDEEMGLQTQQVCHNTSDAPMSLWACVCIYVISALQIFVNSIKRVFNASATGEREPLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NQ85</accession>
    <name>A0A1C7NQ85_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">CS domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_02513</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000096">
        <property type="protein sequence ID" value="OBZ89424.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NQ85"/>
    <dbReference type="STRING" id="101091.A0A1C7NQ85"/>
    <dbReference type="InParanoid" id="A0A1C7NQ85"/>
    <dbReference type="OrthoDB" id="164025at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.790">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052289">
        <property type="entry name" value="Calcyclin-binding_UBL-bridge"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007052">
        <property type="entry name" value="CS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008978">
        <property type="entry name" value="HSP20-like_chaperone"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13164:SF3">
        <property type="entry name" value="CALCYCLIN-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13164">
        <property type="entry name" value="CALICYLIN BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04969">
        <property type="entry name" value="CS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49764">
        <property type="entry name" value="HSP20-like chaperones"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51203">
        <property type="entry name" value="CS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CS" evidence="2">
        <location>
            <begin position="42"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="16"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ89424.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="178" mass="20666" checksum="71678004D8210BF0" modified="2016-11-30" version="1">MLREPDVLKKAPMHMQQKSDTNDSSSIRDPIKKSKAEVQTLYITSGYAWTQSDSSIIRLYINFENANQINQDNCTLDVHSKSFELNILGHSGANRKFRINQLYHPVIEGKFVLKFKENKIVVRLFKETPNKKWPDLRIKSTQTIYNHLERLEKSAALTQVDMDTPFNGSDFCAHHDQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NQB3</accession>
    <name>A0A1C7NQB3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">TBC1 domain family member 5</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">TBC1D5</name>
        <name evidence="4" type="ORF">A0J61_02496</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000095">
        <property type="protein sequence ID" value="OBZ89454.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NQB3"/>
    <dbReference type="STRING" id="101091.A0A1C7NQB3"/>
    <dbReference type="InParanoid" id="A0A1C7NQB3"/>
    <dbReference type="OrthoDB" id="27140at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.472.80:FF:000038">
        <property type="entry name" value="TBC1 domain family member 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.270:FF:000031">
        <property type="entry name" value="TBC1 domain family member 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.270">
        <property type="entry name" value="putative rabgap domain of human tbc1 domain family member 14 like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.80">
        <property type="entry name" value="Ypt/Rab-GAP domain of gyp1p, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000195">
        <property type="entry name" value="Rab-GAP-TBC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035969">
        <property type="entry name" value="Rab-GAP_TBC_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22957:SF337">
        <property type="entry name" value="TBC1 DOMAIN FAMILY MEMBER 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22957">
        <property type="entry name" value="TBC1 DOMAIN FAMILY MEMBER GTPASE-ACTIVATING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00566">
        <property type="entry name" value="RabGAP-TBC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00164">
        <property type="entry name" value="TBC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47923">
        <property type="entry name" value="Ypt/Rab-GAP domain of gyp1p"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50086">
        <property type="entry name" value="TBC_RABGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0343">GTPase activation</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rab-GAP TBC" evidence="3">
        <location>
            <begin position="32"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="551"/>
            <end position="596"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="653"/>
            <end position="694"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="553"/>
            <end position="565"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="566"/>
            <end position="596"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="656"/>
            <end position="675"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022468"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OBZ89454.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="817" mass="93838" checksum="E13709D858228DDC" modified="2016-11-30" version="1" fragment="single">THPSERKAWDVIFNDPNLSLNSLTHRAISGTVCQHGIRSVCWKIFLGYLPTLEITTWSSVLLKERQHYTELKRKFIEEPAEKMNQNDQDQDLSDNNPLALNDNNPWQQYFADSEIRKIIRQDVERTFPDIEFFRQEEAQQRLTDILFIYCKLNRDVSYRQGMHELLAPFYWILKEESLDSTQLNISPIDPINQLLVQLLDSNYAEHDAYILFDRLMKYGKSWYEFNEQTVPVNKKNSTVNRADIRSNPIVAICHRIHHQHLKTIDPYLYQHLENFGIEPQLYGIRWIRLLFGREFEIHELLKLWDAIFAQDRTLEIVEYVCLAILLRMRDQLLNKDYAECLSMLMRPSEQMKPAGLVEQARYLKDNLTEETALQILQQLDVRSGRDPRPSMSAGVPELHIQNASSAPPVRRTLSHKSSQLDGFSRLTSNMMRNSQMRDLNRAIAGVMGTVQKNVNTFNENVLGKPQDLNRRSTVSSEFPSGFDRLATSNNTQSILSSPTQSQKLPLADEQLSRLKATNQEMGELMARCISLLEVQMFPALDVSNKEEEASSEFGISSDFSDQEVSSVRKQEQENNQQEKADSQQQQEEKKQKEVQRPLQDDATIIMALVGLKHVRDVLIGKQTHFDSSVLDFKSSLSQEKKKEEWKWDLVDAKEATPSNETETPSAQTDIPSSASPKADTPPPSSKKTSVFIPPQTTSPLLNAEAYVPNHPVPPKQPIKYRIEDLLSDPDLQIPSPKANHTKFKWILENNHAESPVVAQQDLFKPEPPKLSPRKRASFILKRQPSQVDMASKSSVATIDPLDAKNVDNRKAYEYDVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NQH9</accession>
    <name>A0A1C7NQH9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Global transcription regulator sge1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">sge1_4</name>
        <name evidence="2" type="ORF">A0J61_00575</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000013">
        <property type="protein sequence ID" value="OBZ91367.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="InParanoid" id="A0A1C7NQH9"/>
    <dbReference type="OrthoDB" id="5572844at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018608">
        <property type="entry name" value="Gti1/Pac2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28027">
        <property type="entry name" value="TRANSCRIPTIONAL REGULATOR MIT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28027:SF2">
        <property type="entry name" value="TRANSCRIPTIONAL REGULATOR MIT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09729">
        <property type="entry name" value="Gti1_Pac2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="202"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="301"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="387"/>
            <end position="541"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="307"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="387"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="436"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="486"/>
            <end position="503"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="518"/>
            <end position="531"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="532"/>
            <end position="541"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ91367.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="572" mass="64304" checksum="3CE80515A14FC1DA" modified="2016-11-30" version="1">MLVTETFHGYIETTQDVLLIFEGCRRGLLPRICRRLQERERKMIRSGSIFVFDERESGIKRWTDGRVWSPSRILGNFLIXRELDKKAAGEKKLSQPSMMPTSTRRSFSLDNTLIDRNKERQLIGSLSDSYRFKEDGLIKKTMSIIVNGVAQHLISYYDPNEVLQEKLRSPSSVPELASLEISPELLVKQNFRIPPLVEPTFDLPDHLGHHGHHQQGSLTPPDPAASNSYNRMIHPLRSMSVGSIRGHEQMVMRNEGIMYHPYQQQQQRMGPQSPSLQNHFQHSLSSPNPTNNIPANIYHHDQPHPQTSTSSVFPTTSTSATIPSPSTLTSSPSTPMLSPARYHQQNHQRHYSTSSISSPPLPRFDPRXYTAAAAAAAAAATTESFFDRQSQSNTMGQMMSNPSVDSYHHSAQPPQHNERFASPNIGQLLNPIHPLNSTSTNSTTNNNGNSANDHHTASSSSPSTPPPTGDVFLNHSHQQHPYDYNNVVNPTPTTSSSLRNSISHSDETSENNTQAIPSHHHPSHQNHRHHSIHEMSDHQHGDGVNGYYMNYYQRPSLPDTQIHNGFMFHSQH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NQP9</accession>
    <name>A0A1C7NQP9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">60S ribosomal protein L21-B</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">rpl21b</name>
        <name evidence="4" type="ORF">A0J61_00523</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the eukaryotic ribosomal protein eL21 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000011">
        <property type="protein sequence ID" value="OBZ91447.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NQP9"/>
    <dbReference type="STRING" id="101091.A0A1C7NQP9"/>
    <dbReference type="InParanoid" id="A0A1C7NQP9"/>
    <dbReference type="OrthoDB" id="1539250at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.30.70:FF:000001">
        <property type="entry name" value="60S ribosomal protein L21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.70">
        <property type="entry name" value="Ribosomal protein L21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001147">
        <property type="entry name" value="Ribosomal_eL21"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036948">
        <property type="entry name" value="Ribosomal_eL21_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008991">
        <property type="entry name" value="Translation_prot_SH3-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20981">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01157">
        <property type="entry name" value="Ribosomal_L21e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50104">
        <property type="entry name" value="Translation proteins SH3-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4" id="KW-0689">Ribosomal protein</keyword>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008427"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OBZ91447.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="58" mass="6729" checksum="967BCB8448DB92F5" modified="2016-11-30" version="1" fragment="single">MPHSFGLRARTRHMFSRNFREHGAIPLSTYLKTYKVGDIVDIKANAAVQKGMPHKFYH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-06-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NR82</accession>
    <name>A0A1C7NR82_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_00299</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000006">
        <property type="protein sequence ID" value="OBZ91631.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NR82"/>
    <dbReference type="InParanoid" id="A0A1C7NR82"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ91631.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="74" mass="8873" checksum="F191E3B13BF7EC9A" modified="2016-11-30" version="1">MAVHESFDKQENLYFSQVGLLRQSLFTWNICKPESRQIPAEITRVLQTIYSYRMKKQDAYLDDVKYDTEQYGPF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NRP8</accession>
    <name>A0A1C7NRP8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Four and a half LIM domains protein 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">FHL3</name>
        <name evidence="7" type="ORF">A0J61_02025</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000072">
        <property type="protein sequence ID" value="OBZ89924.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NRP8"/>
    <dbReference type="STRING" id="101091.A0A1C7NRP8"/>
    <dbReference type="InParanoid" id="A0A1C7NRP8"/>
    <dbReference type="OrthoDB" id="1112565at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003712">
        <property type="term" value="F:transcription coregulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd08368">
        <property type="entry name" value="LIM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.110.10">
        <property type="entry name" value="Cysteine Rich Protein"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036280">
        <property type="entry name" value="Multihaem_cyt_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001781">
        <property type="entry name" value="Znf_LIM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24205">
        <property type="entry name" value="FOUR AND A HALF LIM DOMAINS PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24205:SF16">
        <property type="entry name" value="GH01042P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00412">
        <property type="entry name" value="LIM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00132">
        <property type="entry name" value="LIM"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48695">
        <property type="entry name" value="Multiheme cytochromes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00478">
        <property type="entry name" value="LIM_DOMAIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50023">
        <property type="entry name" value="LIM_DOMAIN_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0440">LIM domain</keyword>
    <keyword evidence="1 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 5" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="LIM zinc-binding" evidence="6">
        <location>
            <begin position="71"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="domain" description="LIM zinc-binding" evidence="6">
        <location>
            <begin position="190"/>
            <end position="255"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023038"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OBZ89924.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="270" mass="30337" checksum="BDE152F379038EE8" modified="2016-11-30" version="1">MNIRSTTTTKTECHSCKKKLSGKTVRLPDGSAKYHWHCLQCKGCGLPFEDPSFYIDPFKHIYHPQCAPSIQTCSRCSQAIADTYLHYNTQILHPRCFRCTGCQKILHPTSIYTDFQGPYCQTCTHEKLDQDKQVLSDHLKIVPSPISKNHEMVASPVTPLSPLTQIPENVKPSTLMSSRGRPLPKFGLVRDCAGCHERIVSVHEEIPGPKASKWHKKCLVCQGCLKSLDSGASVDEEEGKLKPWCTTCLLTRKKRMATSLSQRLTTLKIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NSB1</accession>
    <name>A0A1C7NSB1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">mitochondrial processing peptidase</fullName>
            <ecNumber evidence="5">3.4.24.64</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13">Beta-MPP</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="18" type="primary">mppB</name>
        <name evidence="18" type="ORF">A0J61_01800</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18 19">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="14">Catalytic subunit of the essential mitochondrial processing protease (MPP), which cleaves the mitochondrial sequence off newly imported precursors proteins. Preferentially, cleaves after an arginine at position P2.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Release of N-terminal transit peptides from precursor proteins imported into the mitochondrion, typically with Arg in position P2.</text>
            <dbReference type="EC" id="3.4.24.64"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 15">Belongs to the peptidase M16 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.24.64" evidence="5"/>
    <dbReference type="EMBL" id="LUGH01000061">
        <property type="protein sequence ID" value="OBZ90154.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NSB1"/>
    <dbReference type="FunCoup" id="A0A1C7NSB1">
        <property type="interactions" value="667"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NSB1"/>
    <dbReference type="InParanoid" id="A0A1C7NSB1"/>
    <dbReference type="OrthoDB" id="10251424at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017087">
        <property type="term" value="C:mitochondrial processing peptidase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006627">
        <property type="term" value="P:protein processing involved in protein targeting to mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.830.10:FF:000002">
        <property type="entry name" value="Mitochondrial-processing peptidase subunit beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.830.10:FF:000001">
        <property type="entry name" value="Mitochondrial-processing peptidase subunit beta, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.830.10">
        <property type="entry name" value="Metalloenzyme, LuxS/M16 peptidase-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011249">
        <property type="entry name" value="Metalloenz_LuxS/M16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050361">
        <property type="entry name" value="MPP/UQCRC_Complex"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011765">
        <property type="entry name" value="Pept_M16_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001431">
        <property type="entry name" value="Pept_M16_Zn_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007863">
        <property type="entry name" value="Peptidase_M16_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11851:SF149">
        <property type="entry name" value="GH01077P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11851">
        <property type="entry name" value="METALLOPROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00675">
        <property type="entry name" value="Peptidase_M16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05193">
        <property type="entry name" value="Peptidase_M16_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63411">
        <property type="entry name" value="LuxS/MPP-like metallohydrolase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00143">
        <property type="entry name" value="INSULINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="12" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6" id="KW-0645">Protease</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="9" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Peptidase M16 N-terminal" evidence="16">
        <location>
            <begin position="46"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M16 C-terminal" evidence="17">
        <location>
            <begin position="198"/>
            <end position="385"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012299"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00031018"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00045757"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="RuleBase" id="RU004447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF00675"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF05193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="OBZ90154.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="460" mass="51480" checksum="AF4FBE96ABD941C9" modified="2016-11-30" version="1">MSSQFLSRFRKPLINNINYYRHRQLATATNLLPSLRKTILPNGFTVATEENPTSQTATVGVWIDAGSRAENLKNNGAAHFLEHMAFKGTKSRTQRDLELQIENMGGHLNAYTSREQTVYYAKAFKYDVPQAVEILSDILQHSTLDPGAIERERDVILREQEEVEKQMEEVVFDHLHATAFRNESLGLTILGPKENIQSLTRNDLSDYIKTNYTGERMILVGTGGVDHDALVHLASQHFGRLPYQLNASTSKSAMKKAVFTGAEFRIPDAQAQQAHIAVAVEGASWTSPDYFPLLVMQSIIGSWDRSLGATGHMDSRLSSVLHNGQLANSFMSFNTSYKDTGLWGIYLITENKERMEDLLRSTKNEWARLSTSVTHEEVQRAKQQLKAGLLLSLDGSTPIAEDIGRQLLTSGERMSPKQVEDLVGQVTVEDVRRVAREYLQRDAAVVGIGAVDKMPDFNRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NSG8</accession>
    <name>A0A1C7NSG8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_00368</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000008">
        <property type="protein sequence ID" value="OBZ91556.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NSG8"/>
    <dbReference type="InParanoid" id="A0A1C7NSG8"/>
    <dbReference type="OrthoDB" id="2271149at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ91556.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="377" mass="42817" checksum="E0CCCACBCDD0613C" modified="2016-11-30" version="1">MFSNTCFFQDYSDYRHKSFPRKHLLGNKKRQFTKGVRSNPYATPKKMNSDILSRTVLASLKANQGTTVDCYEKPTLYWCAQSVLDYIDIFHDDRSTQISREPHLLNEVYGFIKKSRTISKLTTANGSGSTSSSEAKNKKRKIDGKESFLGQKNGDYFDLVFKPSSVELGCLEKLKTSKMMKAFAMQVIDQFPAVGLNKVKIPLTGMHIEFLKLKHVSSVALLSSSGSYKMSESTLEIPSLLPLVLAVVYSCVQSMKYTNSHLDETSSAFLFIISVGDDLAARIKNLVGNNANWVKRSNRSYPNNIQFVGQSLANPLELESECTAKFMERIITDRFLYVHQWQHVDHKPSNVQKMIKARLLQEVSDRIKEMLTDYINP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NTD4</accession>
    <name>A0A1C7NTD4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Spindle assembly checkpoint component MAD1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">MAD1</name>
        <name evidence="10" type="ORF">A0J61_01200</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the MAD1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000035">
        <property type="protein sequence ID" value="OBZ90754.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NTD4"/>
    <dbReference type="STRING" id="101091.A0A1C7NTD4"/>
    <dbReference type="InParanoid" id="A0A1C7NTD4"/>
    <dbReference type="OrthoDB" id="331602at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000776">
        <property type="term" value="C:kinetochore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072686">
        <property type="term" value="C:mitotic spindle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005635">
        <property type="term" value="C:nuclear envelope"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051315">
        <property type="term" value="P:attachment of mitotic spindle microtubules to kinetochore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007094">
        <property type="term" value="P:mitotic spindle assembly checkpoint signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008672">
        <property type="entry name" value="Mad1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23168:SF0">
        <property type="entry name" value="MITOTIC SPINDLE ASSEMBLY CHECKPOINT PROTEIN MAD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23168">
        <property type="entry name" value="MITOTIC SPINDLE ASSEMBLY CHECKPOINT PROTEIN MAD1 MITOTIC ARREST DEFICIENT-LIKE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05557">
        <property type="entry name" value="MAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="4" id="KW-0132">Cell division</keyword>
    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0498">Mitosis</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="826"/>
            <end position="905"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="24"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="91"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="239"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="309"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="396"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="456"/>
            <end position="500"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="555"/>
            <end position="604"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="834"/>
            <end position="880"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="881"/>
            <end position="905"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008029"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OBZ90754.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="905" mass="104314" checksum="ED3E86867CE2A0F1" modified="2016-11-30" version="1">MSELSLKRKRIDSSVLSFSDGFVSSEKQRDVTKLENLIRKLEHKLSELETKAQSDAITRESAIQEKVATIQKLITSEAEAQRHAVYHKERYDEATQTLATMKEKHNAVANELRSTLEKQRQETRKLESTVQSQTEEIRKLIQQRETDQQVQSIQTKSFESMIASLKASAESDALKMEQALHREAKLNERIHQMEQERTSQYPTSSEAAEKLDAQFQSIIRRSFDLESENHKLKRDLDHYKSISQNVELLRSERDGLQRQAEALSELRATHFQLEAEMAQLRAEQADWAAYVASQPEFKQKKPDSVIYELTRKAEEADFLKRTVEQYQAQVKDQWHVIQSLESHLTELKKEVAEQKERRAIEASARTKLSVGADAWRQYIHLLETQLAVYADQDVGEDTKSKQIAELQQHIQQCQDKITALSQQLAEQEAQKADQAPIQVHLSNGPYEALASGLSLTDFLKQLVEKENQLIEELKQKSVNEAILQKQYDATKEQVERLQTSVRDQQPIQIPSDIVPIQTKQSTSTETQTTQDQDTRYLTVLDNPLSQDYAIRKSLLQRLQKENQSLLDQLADKSGDTILIPAISLENLKIEKTELQATIESRDKRIARLHAVWGNKIQQIVTEIQLLLGYNVNFRNDDLIRLEHALVDPTELAFLVKLETTQDETQGILRFVGSKRDAYMSQLQDIYQTYIIQDRNIPAFLNAAAQDIYVHYKEQHQSIELEMQHTPLDDQLEPYDEETRIHLDTGEDGVAEPMEEMTEQTAFDLFVEEDTIVYDKNEDEIIEESIMAEHVTQTAVSDGEMIEHESDGEMIETEIDQDITEQESEMIEPENEGEMIQHESEGEMVEHESESEMIEHESEGEMIEHESEGELAEHEIEREIIESENDQQENDTVESNDEDITSELSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NU25</accession>
    <name>A0A1C7NU25_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">diphthine methyl ester synthase</fullName>
            <ecNumber evidence="4">2.1.1.314</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">dph-5</name>
        <name evidence="11" type="ORF">A0J61_00941</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">S-adenosyl-L-methionine-dependent methyltransferase that catalyzes four methylations of the modified target histidine residue in translation elongation factor 2 (EF-2), to form an intermediate called diphthine methyl ester. The four successive methylation reactions represent the second step of diphthamide biosynthesis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>2-[(3S)-amino-3-carboxypropyl]-L-histidyl-[translation elongation factor 2] + 4 S-adenosyl-L-methionine = diphthine methyl ester-[translation elongation factor 2] + 4 S-adenosyl-L-homocysteine + 3 H(+)</text>
            <dbReference type="Rhea" id="RHEA:42652"/>
            <dbReference type="Rhea" id="RHEA-COMP:9749"/>
            <dbReference type="Rhea" id="RHEA-COMP:10173"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:73995"/>
            <dbReference type="ChEBI" id="CHEBI:79005"/>
            <dbReference type="EC" id="2.1.1.314"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Protein modification; peptidyl-diphthamide biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the diphthine synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.314" evidence="4"/>
    <dbReference type="EMBL" id="LUGH01000025">
        <property type="protein sequence ID" value="OBZ91014.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NU25"/>
    <dbReference type="FunCoup" id="A0A1C7NU25">
        <property type="interactions" value="721"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NU25"/>
    <dbReference type="InParanoid" id="A0A1C7NU25"/>
    <dbReference type="OrthoDB" id="2516at2759"/>
    <dbReference type="UniPathway" id="UPA00559"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0141133">
        <property type="term" value="F:diphthine methyl ester synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017183">
        <property type="term" value="P:protein histidyl modification to diphthamide"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd11647">
        <property type="entry name" value="DHP5_DphB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.950.10:FF:000004">
        <property type="entry name" value="Diphthine synthase putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.1010.10:FF:000004">
        <property type="entry name" value="Putative diphthine synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1010.10">
        <property type="entry name" value="Cobalt-precorrin-4 Transmethylase, Domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.950.10">
        <property type="entry name" value="Methyltransferase, Cobalt-precorrin-4 Transmethylase, Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01084">
        <property type="entry name" value="Diphthine_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000878">
        <property type="entry name" value="4pyrrol_Mease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035996">
        <property type="entry name" value="4pyrrol_Methylase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014777">
        <property type="entry name" value="4pyrrole_Mease_sub1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014776">
        <property type="entry name" value="4pyrrole_Mease_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004551">
        <property type="entry name" value="Dphthn_synthase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00522">
        <property type="entry name" value="dph5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10882:SF0">
        <property type="entry name" value="DIPHTHINE METHYL ESTER SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10882">
        <property type="entry name" value="DIPHTHINE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00590">
        <property type="entry name" value="TP_methylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036432">
        <property type="entry name" value="Diphthine_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53790">
        <property type="entry name" value="Tetrapyrrole methylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 9" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Tetrapyrrole methylase" evidence="10">
        <location>
            <begin position="1"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="9"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="84"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="87"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="112"/>
            <end position="113"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="163"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="246"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00048752"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR036432-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00590"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="OBZ91014.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="283" mass="31572" checksum="319CDCEC27B85960" modified="2016-11-30" version="1">MLYVVGLGLGDEKDITVAGLEAVKSSERIYLEAYTSILTVGKEKLEDYYGKEVVVADREMVESDSDTILANADTVDVSFLVVGDPYGATTHTDLVIRARELNIPVKVIHNASIMNAIGACGLQLYNFGQTISIVFFTETWRPDSFYDRIKENHRFGLHTLCLLDIKVKEQSIENMARGRLIYEPPRYMTVNQAVEQLLEIEENRQEGICKPSSLAIGCARIGTSTQKIIAGTLEELVDADFGGPLHSLVLIGSRMHEMEAEFVKEYALNPESFMAVVKKDYVH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MTK5</accession>
    <name>A0A1C7MTK5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Tc1-like transposase DDE domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_11771</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01002459">
        <property type="protein sequence ID" value="OBZ80180.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MTK5"/>
    <dbReference type="STRING" id="101091.A0A1C7MTK5"/>
    <dbReference type="InParanoid" id="A0A1C7MTK5"/>
    <dbReference type="OrthoDB" id="2428500at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038717">
        <property type="entry name" value="Tc1-like_DDE_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13358">
        <property type="entry name" value="DDE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tc1-like transposase DDE" evidence="2">
        <location>
            <begin position="108"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="48"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="68"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="193"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13358"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ80180.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="193" mass="21753" checksum="0186509851BEA17D" modified="2016-11-30" version="1" fragment="single">MYFTSSSISLRLIRSANQRNLEMDYATYCVFMDEAGFNAPSKKLLTVNQGNPSQADLTLRKPTPVTKKSTKGKKKRKRNDDSAVEAVEAVEAVEAVEAVEEVNGRVGTRAIQFLVFLDGVLTSLDQNDMTGRYIVMDNVTIHKTDEIRNYIQERGYKAAYLPLYSPFLNPIKEFWAKVKAGVGRDYLTVKDNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MTV8</accession>
    <name>A0A1C7MTV8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Reverse transcriptase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_11650</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01002297">
        <property type="protein sequence ID" value="OBZ80301.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MTV8"/>
    <dbReference type="STRING" id="101091.A0A1C7MTV8"/>
    <dbReference type="InParanoid" id="A0A1C7MTV8"/>
    <dbReference type="OrthoDB" id="2289688at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00303">
        <property type="entry name" value="retropepsin_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01647">
        <property type="entry name" value="RT_LTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.70.10">
        <property type="entry name" value="Acid Proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.10.10">
        <property type="entry name" value="HIV Type 1 Reverse Transcriptase, subunit A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043502">
        <property type="entry name" value="DNA/RNA_pol_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021109">
        <property type="entry name" value="Peptidase_aspartic_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053134">
        <property type="entry name" value="RNA-dir_DNA_polymerase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24559:SF444">
        <property type="entry name" value="REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24559">
        <property type="entry name" value="TRANSPOSON TY3-I GAG-POL POLYPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13650">
        <property type="entry name" value="Asp_protease_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50630">
        <property type="entry name" value="Acid proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56672">
        <property type="entry name" value="DNA/RNA polymerases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="169"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="14"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="172"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="209"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="417"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ80301.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="417" mass="47025" checksum="63C6C0669DC5FB73" modified="2016-11-30" version="1" fragment="single">SNITKPQEKKANQKQDNNVSQSIALLGETEDKLPKGKSAPRTSGTLNGHIAEFILDGGCTSYIISLKLAKEMGIRDVEPCNQSVMFGDGKQYDPIGIAKNIRLQVGDSEVISVNAMCFDVGDRYGFIVGREGLHALRIGTDWSSHFWYLKNDMGTVPLSVHYTKNMTRDQINSDDEEYPEDDDLANDNDYQEDHIDQDDNEEGHLIIEASDDEEGLEDNPIESNDGSNENRLGGLLDRITLYENINNITKAKLIQLVIEYKDCFGTGYEHLSQTNLLKFHVDTGNAKPIYKRPYAFLSLSEKRMLKKDLELMVQQGILVPNTHVPNNSSQSGWSFPCRYVPKKTGDKRLVTNFRELNAVTVRDTWPLPNVIDVLESLAGAHWFGILDLLKAFQQIAVEEDFIQKLTIATPWGNYSYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MU29</accession>
    <name>A0A1C7MU29_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">CENP-B protein 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">cbh2_3</name>
        <name evidence="4" type="ORF">A0J61_11565</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01002200">
        <property type="protein sequence ID" value="OBZ80385.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MU29"/>
    <dbReference type="InParanoid" id="A0A1C7MU29"/>
    <dbReference type="OrthoDB" id="125347at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041188">
        <property type="entry name" value="HTH_ABP1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006600">
        <property type="entry name" value="HTH_CenpB_DNA-bd_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18107">
        <property type="entry name" value="HTH_ABP1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03221">
        <property type="entry name" value="HTH_Tnp_Tc5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51253">
        <property type="entry name" value="HTH_CENPB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH CENPB-type" evidence="3">
        <location>
            <begin position="105"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51253"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OBZ80385.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="178" mass="20585" checksum="F0122E8072F69481" modified="2016-11-30" version="1">MPYHLPNQANSSKIRPSDLTPNHARSLLPRKQQIQAGKKRMRLTDVEKLELGYRCYEVKPKISQESLCAWAKREFQLEEEPIQSTISRALQKYSSLKEPPDNKLRAFSSKGAKFSLLESKFADFVKRMEDSSFAINSHSLKAEAERLCMSEPLLLNGELMPAFSNGWFDRFMKRNMLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MUC6</accession>
    <name>A0A1C7MUC6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Swc3 C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_11456</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01002051">
        <property type="protein sequence ID" value="OBZ80495.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MUC6"/>
    <dbReference type="STRING" id="101091.A0A1C7MUC6"/>
    <dbReference type="InParanoid" id="A0A1C7MUC6"/>
    <dbReference type="OrthoDB" id="2162994at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000812">
        <property type="term" value="C:Swr1 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140849">
        <property type="term" value="F:ATP-dependent H2AZ histone chaperone activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037651">
        <property type="entry name" value="Swc3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058986">
        <property type="entry name" value="Swc3_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28108">
        <property type="entry name" value="SWR1-COMPLEX PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28108:SF1">
        <property type="entry name" value="SWR1-COMPLEX PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26242">
        <property type="entry name" value="Swc3_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Swc3 C-terminal" evidence="2">
        <location>
            <begin position="188"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="140"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="157"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="353"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF26242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ80495.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="353" mass="40917" checksum="555543B807702181" modified="2016-11-30" version="1" fragment="single">MSTSGLIAAKKRIENAVRRYDVPTDTKPNQVDRCENGALLLSLLQSRLNWTNAVFARYKMDSLQQPKRTTSSRKKWPNMRYLGTCDLEIGAHLFEQTIFYEAIRTETWRSIAEKQGLHVPEKKTTQVMPDAELLPDASPALLESGSEEPPQNEEEQNEPKEMSSIEEGRQIETNQSEEEEEEKLIYMDIVFELREFPNERFVFPKETIVEAIPLSSTEYNMLASFTIPFDSDPAEAFFLPAKEKILKYGHTSQLDCIKQFLQLEPPETREAKARTLKHECYEPVTIQLTNTNQETVKALQGYVDDMEKVRKRMKEKMKLFPQHTYIQFDLPKEDPQSIEMLDLVRKAAFIPDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MUM1</accession>
    <name>A0A1C7MUM1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">U3 small nucleolar RNA-associated protein 21</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">A0J61_11376</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001968">
        <property type="protein sequence ID" value="OBZ80575.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MUM1"/>
    <dbReference type="STRING" id="101091.A0A1C7MUM1"/>
    <dbReference type="InParanoid" id="A0A1C7MUM1"/>
    <dbReference type="OrthoDB" id="10250769at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034388">
        <property type="term" value="C:Pwp2p-containing subcomplex of 90S preribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032040">
        <property type="term" value="C:small-subunit processome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007319">
        <property type="entry name" value="WDR36/Utp21_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22840">
        <property type="entry name" value="WD REPEAT-CONTAINING PROTEIN 36"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22840:SF12">
        <property type="entry name" value="WD REPEAT-CONTAINING PROTEIN 36"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25168">
        <property type="entry name" value="Beta-prop_WDR36-Utp21_2nd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04192">
        <property type="entry name" value="Utp21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="33"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="domain" description="WDR36/Utp21 C-terminal" evidence="5">
        <location>
            <begin position="162"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="131"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="139"/>
            <end position="153"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF04192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OBZ80575.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="373" mass="42448" checksum="84568E1DB00989CB" modified="2016-11-30" version="1">MRYHIDNDLLAVVCDDLGIRVIDLETKNIIREFWGHRNRITDFVFSSDSRWIVSASLDGTVRTWDLPTGAMVDIFRVQDIVTCLAFSPDGDFLATGHVDHVGIFLWSNRTQYTNVSLRNITDDQDIKELSLPSLSGGLDSDEEDESDEDAEFADQDKLDTVDQLADQMITLSMEPRAKWQNLLHLDTIKLRNKPKEAPKLPEKAPFFLPTLPGAKAQFDLDAAKDEKDQDATGEKSRQLNFSQLNTDTQFAKELRAGHEANRQYHTFVEYAKSLSPSAIDVEIRSFSIDPELSLLNHYLEAILYMLETRKNFELAQAWLSVFLNIHGDLIVSNPTNSIHDKLQSILDIQGAEFGRLSQQIHYSLCLIDFARRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-06-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MUU0</accession>
    <name>A0A1C7MUU0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_11712</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01002375">
        <property type="protein sequence ID" value="OBZ80239.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MUU0"/>
    <dbReference type="InParanoid" id="A0A1C7MUU0"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="40"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="171"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ80239.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="171" mass="19802" checksum="A95608DA76DA624F" modified="2016-11-30" version="1" fragment="single">MSHFTGTNNTYNVSSNKGISSVRTTTRLPTARSSVSDRRIANLEAAVTQLTREREEDRAEILALKRKNEELDAKLKKQRENNKLFGFPGSENELESLRQIIKRIEKKHVGADGWDLSETLMRRPTNNKKVKAIIDDFYVDTEVLILTRNYVWLREDMQAFVKSKLTQRFKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MV37</accession>
    <name>A0A1C7MV37_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_11271</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001847">
        <property type="protein sequence ID" value="OBZ80680.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MV37"/>
    <dbReference type="InParanoid" id="A0A1C7MV37"/>
    <dbReference type="OrthoDB" id="2285904at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="161"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="166"/>
            <end position="181"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ80680.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="181" mass="20442" checksum="99FCFAD4668D8AB9" modified="2016-11-30" version="1">MLNYAFLVDDAGAISSQESRGKALSDILPTSGSSSNQEFLPPPLTTNCVESRAFEKLYKNIFNQGHLQIIHSAYFGPIRTKQDTLNKNPIIKVFVDAMPPREDEKCNVDTYLMKKAYSMYFRLAIPKGKLKQQEEPNLIDDDNNELLDLMNLAEELPAAEGRILELEDDATQDNNDTPEEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MVB2</accession>
    <name>A0A1C7MVB2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_11191</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001762">
        <property type="protein sequence ID" value="OBZ80760.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MVB2"/>
    <dbReference type="STRING" id="101091.A0A1C7MVB2"/>
    <dbReference type="InParanoid" id="A0A1C7MVB2"/>
    <dbReference type="OrthoDB" id="2426083at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="unsure residue" description="I or L" evidence="1">
        <location>
            <position position="83"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="189"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ80760.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="189" mass="21265" checksum="8C6A79873159D8F4" modified="2016-11-30" version="1" fragment="single">MHSCRSLSVMGRATVINSLILSQCWFLFRVVPIPKSSLQAIRSLVSSFMNHSIFPRCGWHILTASKKEGGFGLLDPELQQSALYYRWLDPFLFPRPDHSMVHDFFRAHLCTSFLSSQPLIGLLFPRARPHATPGANLTTVSMVCGTMDAIPRRQFTYIPNPIECLLLPLRAVVIPSASFRLSPILRDAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MW39</accession>
    <name>A0A1C7MW39_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Reverse transcriptase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_10901</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001499">
        <property type="protein sequence ID" value="OBZ81050.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MW39"/>
    <dbReference type="STRING" id="101091.A0A1C7MW39"/>
    <dbReference type="InParanoid" id="A0A1C7MW39"/>
    <dbReference type="OrthoDB" id="2417874at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043502">
        <property type="entry name" value="DNA/RNA_pol_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000477">
        <property type="entry name" value="RT_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31635">
        <property type="entry name" value="REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31635:SF196">
        <property type="entry name" value="REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00078">
        <property type="entry name" value="RVT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56672">
        <property type="entry name" value="DNA/RNA polymerases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50878">
        <property type="entry name" value="RT_POL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Reverse transcriptase" evidence="1">
        <location>
            <begin position="1"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ81050.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="311" mass="36310" checksum="0ACAA33AB39D4542" modified="2016-11-30" version="1" fragment="single">ARSLHQGDPLSPLLFNLVFEHLLLFIQQDTQYHGYRPVKKKSIQEIKCIAYADDICVFVRHPEDFLRLQSHLLGYAKVSNARFNLFTTNSITTYYTKFSPNSLRYLGYPMAYTVPQQKVAEENLLETVRSAVAHYARRSLSFRGKITILNTLILSEVWYSLRLLRVTTKTLETIQSLCYQFVWMGKTPRLAFDTICLPRTQGGLGVINPYRHYLVLQMKWLFALFSTTNSPIRKLLTHHFALLQNTDNDPLFSFYSPEHRPLSNINPTSIVHFLYKTFDYPDVHFTLDRVPLNLLLRLSLRRMFVSVSTNY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MWG0</accession>
    <name>A0A1C7MWG0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Large ribosomal subunit protein uL4m</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">rplD</name>
        <name evidence="6" type="ORF">A0J61_10843</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uL4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001436">
        <property type="protein sequence ID" value="OBZ81108.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MWG0"/>
    <dbReference type="FunCoup" id="A0A1C7MWG0">
        <property type="interactions" value="252"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7MWG0"/>
    <dbReference type="InParanoid" id="A0A1C7MWG0"/>
    <dbReference type="OrthoDB" id="275876at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1370.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01328_B">
        <property type="entry name" value="Ribosomal_uL4_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002136">
        <property type="entry name" value="Ribosomal_uL4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013005">
        <property type="entry name" value="Ribosomal_uL4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023574">
        <property type="entry name" value="Ribosomal_uL4_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR03953">
        <property type="entry name" value="rplD_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10746">
        <property type="entry name" value="50S RIBOSOMAL PROTEIN L4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10746:SF6">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN UL4M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00573">
        <property type="entry name" value="Ribosomal_L4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52166">
        <property type="entry name" value="Ribosomal protein L4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 6" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="69"/>
            <end position="103"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00040565"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OBZ81108.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="235" mass="25985" checksum="671F412774DFAD3D" modified="2016-11-30" version="1">MEVAPIQKRAFATALETAPKAFPTTVQAFLRDFKTNEPISIIDLDKTVFGAPIRRDILHRVVVWQRDAMRQGTHSTKTRSEVNGTGKKQAPQKGRGKARIGDGKAPHIKGGGIAFGPKPRDHSTDLPRKVQEMGLRVALSTKYAQDQLIVVESLQDLATHKTRDLNNILISSYGSPKTLVVIDDCNFNLELAARNIPNCEVIHVEETNVLDLLTYDKLIIEKSAVEALESVLKAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MWN4</accession>
    <name>A0A1C7MWN4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_10740</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001358">
        <property type="protein sequence ID" value="OBZ81211.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MWN4"/>
    <dbReference type="InParanoid" id="A0A1C7MWN4"/>
    <dbReference type="OrthoDB" id="2226789at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ81211.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="102" mass="12084" checksum="EFAB9404A618FC54" modified="2016-11-30" version="1">MSSENIPQEYFNCFNFNSELPPADPTEVEELQQDLYETAAMEWHHWQPGRDFEPKSKKAEAEPNLKRLMNFYGFLQTQHEAHKPEKHEKFVESVNKKISWGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MWT5</accession>
    <name>A0A1C7MWT5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Putative transporter C11D3.06</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">A0J61_10664</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001299">
        <property type="protein sequence ID" value="OBZ81287.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MWT5"/>
    <dbReference type="FunCoup" id="A0A1C7MWT5">
        <property type="interactions" value="36"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7MWT5"/>
    <dbReference type="InParanoid" id="A0A1C7MWT5"/>
    <dbReference type="OrthoDB" id="2126698at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015297">
        <property type="term" value="F:antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042910">
        <property type="term" value="F:xenobiotic transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990961">
        <property type="term" value="P:xenobiotic detoxification by transmembrane export across the plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd13132">
        <property type="entry name" value="MATE_eukaryotic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045069">
        <property type="entry name" value="MATE_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002528">
        <property type="entry name" value="MATE_fam"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00797">
        <property type="entry name" value="matE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11206">
        <property type="entry name" value="MULTIDRUG RESISTANCE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01554">
        <property type="entry name" value="MatE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="126"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="157"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="190"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="218"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="262"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="303"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="344"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="383"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="412"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="439"/>
            <end position="464"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OBZ81287.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="491" mass="53908" checksum="F489E37D65884C8A" modified="2016-11-30" version="1">MQEHRIDCQDNDSQHSVSITLNESTPLINKSLDHTTVQRELKWLLINSLPIIGTYFLQNSFQLASIFTLGHLGETELGASALASMFVNVSAWSISYGITSALDTLCSQAWTASKDKTVIGVHLQRAYLVLMILFMPIACIWWNATSIMLSFDQEPELARFAGLFLRYLLPGAPAYMGFEATKRYLQAQGIMHASTLSMLVTAPINFVLNYLFVYTLDFGFIGAPLATSLSYWLMFALLLVYIKYVKGSEGWGGWSRECLTEWWPFLRLASSGIVIICAEWAAFEMSSLAASYLGTTDLAAQSILLTLSSATYTVPMGIAVAATNRVGNFLGAGLASNARVASKGALLFSVMFALINSTFFMVTRQQIGYLFTSEPKVASLVAHVLPLCAVFQVTDGIASVGGGVIRGLGRQGVAAMINLIAYYVIALPIGFYLTFRALWALTGLWAGLSIALFLVAAGEVMFLSRVDWFLEMKRAKQRCRSSQEDKSVRNV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MXE0</accession>
    <name>A0A1C7MXE0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Glutathione synthetase</fullName>
            <shortName evidence="10">GSH-S</shortName>
            <ecNumber evidence="10">6.3.2.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="primary">gshB</name>
        <name evidence="15" type="ORF">A0J61_10469</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>gamma-L-glutamyl-L-cysteine + glycine + ATP = glutathione + ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13557"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57305"/>
            <dbReference type="ChEBI" id="CHEBI:57925"/>
            <dbReference type="ChEBI" id="CHEBI:58173"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.2.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="10 12">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="10 12">Binds 1 Mg(2+) ion per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1 10">Sulfur metabolism; glutathione biosynthesis; glutathione from L-cysteine and L-glutamate: step 2/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the eukaryotic GSH synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.2.3" evidence="10"/>
    <dbReference type="EMBL" id="LUGH01001189">
        <property type="protein sequence ID" value="OBZ81482.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="FunCoup" id="A0A1C7MXE0">
        <property type="interactions" value="692"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7MXE0"/>
    <dbReference type="InParanoid" id="A0A1C7MXE0"/>
    <dbReference type="OrthoDB" id="2020073at2759"/>
    <dbReference type="UniPathway" id="UPA00142">
        <property type="reaction ID" value="UER00210"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043295">
        <property type="term" value="F:glutathione binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004363">
        <property type="term" value="F:glutathione synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1490.50:FF:000002">
        <property type="entry name" value="Glutathione synthetase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1760:FF:000001">
        <property type="entry name" value="Glutathione synthetase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.470.20">
        <property type="entry name" value="ATP-grasp fold, B domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1760">
        <property type="entry name" value="Glutathione synthase, substrate-binding domain superfamily, eukaryotic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1080.10">
        <property type="entry name" value="Glutathione Synthetase, Chain A, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005615">
        <property type="entry name" value="Glutathione_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014042">
        <property type="entry name" value="Glutathione_synthase_a-hlx"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014709">
        <property type="entry name" value="Glutathione_synthase_C_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014049">
        <property type="entry name" value="Glutathione_synthase_N_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037013">
        <property type="entry name" value="GSH-S_sub-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004887">
        <property type="entry name" value="GSH_synth_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016185">
        <property type="entry name" value="PreATP-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01986">
        <property type="entry name" value="glut_syn_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11130">
        <property type="entry name" value="GLUTATHIONE SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11130:SF0">
        <property type="entry name" value="GLUTATHIONE SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03917">
        <property type="entry name" value="GSH_synth_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03199">
        <property type="entry name" value="GSH_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001558">
        <property type="entry name" value="GSHase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56059">
        <property type="entry name" value="Glutathione synthetase ATP-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52440">
        <property type="entry name" value="PreATP-grasp domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 10 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 10" id="KW-0317">Glutathione biosynthesis</keyword>
    <keyword evidence="4 10" id="KW-0436">Ligase</keyword>
    <keyword evidence="9 10 12" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6 10 12" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 10 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glutathione synthase substrate-binding" evidence="14">
        <location>
            <begin position="208"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="121"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="143"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="143"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="145"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <begin position="147"/>
            <end position="150"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <begin position="217"/>
            <end position="219"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="223"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <begin position="272"/>
            <end position="275"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="311"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="368"/>
            <end position="377"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="372"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="379"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="401"/>
            <end position="404"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="427"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="452"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="454"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="460"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <begin position="463"/>
            <end position="464"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004965"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010385"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRNR" id="PIRNR001558"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR001558-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR001558-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR001558-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF03199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="OBZ81482.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="476" mass="53316" checksum="F9F550950FE0F3FA" modified="2016-11-30" version="1">MYSPKDLEQTVSLAIDWALSHGLVVRPPVDKQVHFTNNAAVTHAPFXLYPTPFPRGEYEKAKALQAPWNALIHQMSRDDSLIEETMESLSKLDDFMNQLYKIYLTVKEEGIVQTASLGIHRNDYLLHAEEGADAKSAKIQQVEFNTISASFMSLSHRTTELHRYLLSTSKGYAGGQIKMDQLPVNKAIDTIANGLAVGWKHYNKPSAYVAMIVQPGERNAFDQRWIEYKLLEDHNIHLVRLSLEDIADRATLDSETKALIIDDLEIAVTYYRAGYGPEDYHSQKEWDARLMIERSLSIKCPTVAYQLVGSKKVQQVLAEPGRLERYVDQQTADAIRESFAGLYPLDSSPEGVAAYEKALSQPDNLVMKPQREGGGHNIYGQDILAELKRLSPEERNAYILMDLIRSPPLDNYMVREGQVIAGQVVSELGIYGIYLGDGDKQLFNHTDGHLLRTKAITTREGGVAAGFAVIDSPLLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MXE9</accession>
    <name>A0A1C7MXE9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_10367</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001138">
        <property type="protein sequence ID" value="OBZ81585.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MXE9"/>
    <dbReference type="InParanoid" id="A0A1C7MXE9"/>
    <dbReference type="OrthoDB" id="2266007at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ81585.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="195" mass="23017" checksum="C8AB1348B220CFA5" modified="2016-11-30" version="1">MSVGTRLKRKNTVGIDEFIASDTFLETNTGKQGRPSQGGDLIKAKRYYVKNHMLILHKRKLKRYHDKVKKWLLFYEHDPHKIMKAFETSFSRYTKDHHHFFYAINQLREDGYVRLLNEEAERYLGERFGIDPEKEQVLAICQTLTDGHLLLLFKLCTLFSAFLLASYLKKECGDDREKLESVCSQEYMISYAHIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MXK0</accession>
    <name>A0A1C7MXK0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">60S ribosomal protein L12</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">A0J61_10386</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the universal ribosomal protein uL11 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001147">
        <property type="protein sequence ID" value="OBZ81567.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MXK0"/>
    <dbReference type="FunCoup" id="A0A1C7MXK0">
        <property type="interactions" value="435"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7MXK0"/>
    <dbReference type="InParanoid" id="A0A1C7MXK0"/>
    <dbReference type="OrthoDB" id="1478556at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022625">
        <property type="term" value="C:cytosolic large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070180">
        <property type="term" value="F:large ribosomal subunit rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002181">
        <property type="term" value="P:cytoplasmic translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000027">
        <property type="term" value="P:ribosomal large subunit assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd00349">
        <property type="entry name" value="Ribosomal_L11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.250:FF:000002">
        <property type="entry name" value="60S ribosomal protein L12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1550.10:FF:000002">
        <property type="entry name" value="60S ribosomal protein L12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.250">
        <property type="entry name" value="Ribosomal protein L11, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1550.10">
        <property type="entry name" value="Ribosomal protein L11/L12, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00736">
        <property type="entry name" value="Ribosomal_uL11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000911">
        <property type="entry name" value="Ribosomal_uL11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020783">
        <property type="entry name" value="Ribosomal_uL11_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036769">
        <property type="entry name" value="Ribosomal_uL11_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020785">
        <property type="entry name" value="Ribosomal_uL11_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020784">
        <property type="entry name" value="Ribosomal_uL11_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036796">
        <property type="entry name" value="Ribosomal_uL11_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11661">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11661:SF2">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN UL11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00298">
        <property type="entry name" value="Ribosomal_L11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03946">
        <property type="entry name" value="Ribosomal_L11_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00649">
        <property type="entry name" value="RL11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54747">
        <property type="entry name" value="Ribosomal L11/L12e N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46906">
        <property type="entry name" value="Ribosomal protein L11, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00359">
        <property type="entry name" value="RIBOSOMAL_L11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 7" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Large ribosomal subunit protein uL11 N-terminal" evidence="6">
        <location>
            <begin position="13"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="domain" description="Large ribosomal subunit protein uL11 C-terminal" evidence="5">
        <location>
            <begin position="74"/>
            <end position="143"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010537"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003978"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00298"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF03946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OBZ81567.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="165" mass="17713" checksum="A658F2677CF88C0F" modified="2016-11-30" version="1">MPPKFDPSEVKIIYLRATGGEVGASSALAPKIGPLGLSPKKVGEDIAKGTKDWKGLRVTVQLTIQNRQAQVSVVPSASSLVIKALKEPVRDRKKEKNIKHTGNISLDDVIEIARTMRFKSLARELKGTVKEILGTAFSVGCTVDGQNPKDLGDAIDAGEVEIPEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MXR0</accession>
    <name>A0A1C7MXR0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_10325</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001119">
        <property type="protein sequence ID" value="OBZ81627.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MXR0"/>
    <dbReference type="InParanoid" id="A0A1C7MXR0"/>
    <dbReference type="OrthoDB" id="2287714at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ81627.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="180" mass="19798" checksum="B478153DEA02A6E1" modified="2016-11-30" version="1" fragment="single">NFPLHTSRLHPMSAPGEIPWAKVAERGHQLRVPLSSKSHHQDSTVKYVPEIIFQTPDFETELLNRRAASIVHQTLTTGSVIFKFPPGTFANHLEAYEAIDTELGPVEGFQHLSGFTPNPYKGDMLIEARFESTESRDRAIQTGLVVGDATFRGTASSSGTSSTSFVHVALNRVGKWNGII</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MXY5</accession>
    <name>A0A1C7MXY5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Global transcription regulator sge1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">sge1_2</name>
        <name evidence="1" type="ORF">A0J61_10702</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001329">
        <property type="protein sequence ID" value="OBZ81249.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="InParanoid" id="A0A1C7MXY5"/>
    <dbReference type="OrthoDB" id="5572844at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018608">
        <property type="entry name" value="Gti1/Pac2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28027">
        <property type="entry name" value="TRANSCRIPTIONAL REGULATOR MIT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28027:SF2">
        <property type="entry name" value="TRANSCRIPTIONAL REGULATOR MIT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09729">
        <property type="entry name" value="Gti1_Pac2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ81249.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="253" mass="29395" checksum="1A96A21974D73AE5" modified="2016-11-30" version="1">MSFPXTFHGYIGDMTDTMLVIEACRHGVLPTISRRLLEKERNSIMSGTIIVFEESESGIKRWTDGFLWSPSRILGNFLVYRELKSRENRKKKGQQTDRQQTNQTLEKERALVGSLTASNTIYNFKEDGLIKKTIRLHINGKHLHIINYYNKNDVLNNLLQTPSSNPQFAYLQISPDLMLHLPWQMEDPSKERKRSYTIPTQVKRRTYSYDASIPVYPPYPIHMLSSHCGKRDILCHPNRLLGSHQVDIAHFPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MXZ1</accession>
    <name>A0A1C7MXZ1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Pre-mRNA-splicing factor CWC22</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">CWC22</name>
        <name evidence="8" type="ORF">A0J61_10272</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the CWC22 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001098">
        <property type="protein sequence ID" value="OBZ81678.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MXZ1"/>
    <dbReference type="FunCoup" id="A0A1C7MXZ1">
        <property type="interactions" value="920"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7MXZ1"/>
    <dbReference type="InParanoid" id="A0A1C7MXZ1"/>
    <dbReference type="OrthoDB" id="1924287at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071013">
        <property type="term" value="C:catalytic step 2 spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.180:FF:000004">
        <property type="entry name" value="pre-mRNA-splicing factor CWC22 homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.180">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050781">
        <property type="entry name" value="CWC22_splicing_factor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003891">
        <property type="entry name" value="Initiation_fac_eIF4g_MI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003890">
        <property type="entry name" value="MIF4G-like_typ-3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18034">
        <property type="entry name" value="CELL CYCLE CONTROL PROTEIN CWF22-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18034:SF3">
        <property type="entry name" value="PRE-MRNA-SPLICING FACTOR CWC22 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02847">
        <property type="entry name" value="MA3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02854">
        <property type="entry name" value="MIF4G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00544">
        <property type="entry name" value="MA3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00543">
        <property type="entry name" value="MIF4G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51366">
        <property type="entry name" value="MI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="4" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MI" evidence="7">
        <location>
            <begin position="344"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="299"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="541"/>
            <end position="702"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="300"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="543"/>
            <end position="611"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="612"/>
            <end position="632"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="633"/>
            <end position="655"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="656"/>
            <end position="676"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="686"/>
            <end position="702"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006856"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51366"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OBZ81678.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="702" mass="80929" checksum="BEAF80C701CC0D86" modified="2016-11-30" version="1">MSSEVETATGRVDALKLSNTRAGGAYIPPHRLRQMQQSITDTSSEEYQRITWEALKKSINGLINKVNTSNIKMIIPELFGENLVRGRGLYCRSMMKAQQASLPFTPVYAAVTAVVNTKLPAVGALLLSRLVLQFRRAYRRNDKTSCLATTMFIAHLTNQLIADKVLALQILALLLERPTDDSVEIAVGFMREVGALLAQICPKANNAIYERFRAVLHEGEIDKRVQYMIEVLFQVRKDKYKDNQPVAQELDLVEEEDQITHNISLDDDDLEAEEMLNIFKFDPNYTENEERYNAIKAEILGDDEDQSGSDDESGSGSEESSEEEEDEEESKFEMLDKTNADVIEVRRKIYLTVMSSVNFEEACHKLMKINIPEGYEIELCNMIIECCSQERTYLKYYGLMAERFCKMNREWVDNFTHCFKDVYETIHRYETNRLRNIGKLFAHLFNTDSLPWTSFEIIRLTEEETTSASRIFVKILFQEINEFLGLKTLKERLLDPYMSESLAGMFPKDNPKNTRFAINYWTSIGLGAITEDLREWLRTAPQQSMRQNDSSDSDSDSSSSSTSSSSSSDSDSDSSSVSSRSSRSSMSTRSSRSRSRSSSYSRSDSVSSRSLSRSRNRKRYRSLSRSPSRRRRSPIDRRRRSPSDRRRRSPSDRRRSFSRSRSPSRSRVRKRSRYRSPSRSPSRSHSPVRRRRERSRTPIRRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MYQ7</accession>
    <name>A0A1C7MYQ7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">BOD1/SHG1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_10006</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001000">
        <property type="protein sequence ID" value="OBZ81943.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MYQ7"/>
    <dbReference type="STRING" id="101091.A0A1C7MYQ7"/>
    <dbReference type="InParanoid" id="A0A1C7MYQ7"/>
    <dbReference type="OrthoDB" id="5579731at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055264">
        <property type="entry name" value="BOD1/SHG1_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05205">
        <property type="entry name" value="COMPASS-Shg1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BOD1/SHG1" evidence="1">
        <location>
            <begin position="7"/>
            <end position="97"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF05205"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ81943.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="111" mass="13074" checksum="33B2E93050FA64A3" modified="2016-11-30" version="1">MTPEETVLQLKRNGTFDELRKKLLSDFQSQTTGQKFLDDLKEFMEDLVQKSPSLLDTEPSTFHEQVMTELEKAGIYQQIRKEALETLKGDYYQQRVDKEIQLLEDNSKKEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MYU7</accession>
    <name>A0A1C7MYU7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">D-lactate dehydratase</fullName>
            <ecNumber evidence="1">4.2.1.130</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">park7</name>
        <name evidence="4" type="ORF">A0J61_09967</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>methylglyoxal + H2O = (R)-lactate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:27754"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16004"/>
            <dbReference type="ChEBI" id="CHEBI:17158"/>
            <dbReference type="EC" id="4.2.1.130"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.130" evidence="1"/>
    <dbReference type="EMBL" id="LUGH01000986">
        <property type="protein sequence ID" value="OBZ81983.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MYU7"/>
    <dbReference type="FunCoup" id="A0A1C7MYU7">
        <property type="interactions" value="251"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7MYU7"/>
    <dbReference type="InParanoid" id="A0A1C7MYU7"/>
    <dbReference type="OrthoDB" id="543156at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019172">
        <property type="term" value="F:glyoxalase III activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:1903189">
        <property type="term" value="P:glyoxal metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006979">
        <property type="term" value="P:response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd03135">
        <property type="entry name" value="GATase1_DJ-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006287">
        <property type="entry name" value="DJ-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002818">
        <property type="entry name" value="DJ-1/PfpI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050325">
        <property type="entry name" value="Prot/Nucl_acid_deglycase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01383">
        <property type="entry name" value="not_thiJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48094:SF12">
        <property type="entry name" value="PARKINSON DISEASE PROTEIN 7 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48094">
        <property type="entry name" value="PROTEIN/NUCLEIC ACID DEGLYCASE DJ-1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01965">
        <property type="entry name" value="DJ-1_PfpI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="Class I glutamine amidotransferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DJ-1/PfpI" evidence="3">
        <location>
            <begin position="5"/>
            <end position="174"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00013134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00048082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01965"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OBZ81983.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="194" mass="21086" checksum="6CD908483659EE6B" modified="2016-11-30" version="1">MSEQKKAIVFLADGTEEMEFTISAVDVLRRAKVDVTVVGVQLEKDYAVCSRGVKVLPDAKFEDINIDASQYDLVLIPGGAGGAKTLAAHEGIQKLIFDFYNKKKFVAFVCAGTLVAKAAGIPYKHKVTSYPGAVKEQLVSLYNYSDDRVVVDDNVITSRGPGTTFLFALTIVEQLVDAKTSEALREEMLTSADL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MZL3</accession>
    <name>A0A1C7MZL3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_09689</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000910">
        <property type="protein sequence ID" value="OBZ82263.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MZL3"/>
    <dbReference type="InParanoid" id="A0A1C7MZL3"/>
    <dbReference type="OrthoDB" id="2274890at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="157"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="215"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="162"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="225"/>
            <end position="236"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ82263.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="407" mass="46265" checksum="9679CC49D811AD3D" modified="2016-11-30" version="1">MESIISTFVGVFFPHTIEIVDVEQKVYFLLYEPRSARYSVKAIADREMVEKSLLDYDEAWTLDCIKTKKEPIIVSATGPMKQMPSVTGFLGRAMEEKFHITPLALQVIPCIPLVTEKLKDMVHPEVGPTVLEEGVKEGYFFVNLSLNQNFDDGAEFFGIDTNNRDQNEHDIDDNHNEENQHADEEEIVDPLEETGPSQQRDTEADDEFLFLNQLNDDEDARRFSDNSSIGSGDNNDAANRMRFVSDFDSFDHQEINVSNDTQRHLNETSKLASSNVYDDGEDFGTQIISAMYRSDSSERTIRQARPTTSATLANRNKPVHCYQPIIRPSYFEAESSTAFQFTEDNFEEERIDYSDNNINYERNICNSGLQKCTGEGKQRAEVSIVAASQNLKWPLHLAIQAPDLPLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N051</accession>
    <name>A0A1C7N051_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Anaphase-promoting complex subunit 1 N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">A0J61_09421</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000847">
        <property type="protein sequence ID" value="OBZ82525.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N051"/>
    <dbReference type="STRING" id="101091.A0A1C7N051"/>
    <dbReference type="InParanoid" id="A0A1C7N051"/>
    <dbReference type="OrthoDB" id="26401at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005680">
        <property type="term" value="C:anaphase-promoting complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0060090">
        <property type="term" value="F:molecular adaptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031145">
        <property type="term" value="P:anaphase-promoting complex-dependent catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007091">
        <property type="term" value="P:metaphase/anaphase transition of mitotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070979">
        <property type="term" value="P:protein K11-linked ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024990">
        <property type="entry name" value="Apc1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049255">
        <property type="entry name" value="Apc1_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12827:SF3">
        <property type="entry name" value="ANAPHASE-PROMOTING COMPLEX SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12827">
        <property type="entry name" value="MEIOTIC CHECKPOINT REGULATOR TSG24 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12859">
        <property type="entry name" value="ANAPC1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="1" id="KW-0132">Cell division</keyword>
    <keyword evidence="2" id="KW-0498">Mitosis</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Anaphase-promoting complex subunit 1 N-terminal" evidence="5">
        <location>
            <begin position="84"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="domain" description="Anaphase-promoting complex subunit 1 N-terminal" evidence="5">
        <location>
            <begin position="259"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="239"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="245"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="616"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF12859"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OBZ82525.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="616" mass="71574" checksum="AE8118AD678B80E2" modified="2016-11-30" version="1" fragment="single">MLSKIDRYQSIGQAFLTKHSHLGQYRNTNAEFDISTINQRSSNKPIYHAEDRCQLFSVSDAPTMVIGEPLDIQPVQGQIDNWALALDQELYIKNATVVVWSRGTHILKTFDFSQENQKVKQVLFAWFPIPTNQAENKHTSAQQVDLNDANSRMQWVKKYWHKRGPQALLMDEKKPVFESVDKPMFENTDLRRRALCIVFLDRIQIHFEDGINFTAYIPFEIDNVVPLDIGLLISERPDAEHSKQKSSPQLSIPSGNSTTSWNISSRFVSITHPLLMPCPVKIERIHSSSTNSIPSTLSNYSHRLLFATAQTSNEERPPVIVTLNLNDNKHSIWMYERQKYRIKPMKGAPQKTRSREEFQARKRKRSSSLSFYDELNELNQKELQVYHTILDPSELSLTKLWQEQKRFNKRLGKRPIRTNPDNIKSTAFLVHNLNGEELICLHNTTTNQLQLINLEKAFQKDTNIIEFKSTAKSAISVNATRDSCKDLLFLDVDGHLWLWVDGRMPLISVPLPSSQPVIDISQNVYDRFNLQYQNETIRYRIHLQPKSSIVRNCLAAFDCAHTPFFATFWYRFIQLKQQHVDWTEWHVLFVSLLSFIPLKRTQRRLAKKILVGEGRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N097</accession>
    <name>A0A1C7N097_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="15">Putative general negative regulator of transcription C16C9.04c</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">A0J61_09434</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000849">
        <property type="protein sequence ID" value="OBZ82517.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N097"/>
    <dbReference type="InParanoid" id="A0A1C7N097"/>
    <dbReference type="OrthoDB" id="1923159at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030014">
        <property type="term" value="C:CCR4-NOT complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004842">
        <property type="term" value="F:ubiquitin-protein transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016567">
        <property type="term" value="P:protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd16618">
        <property type="entry name" value="mRING-HC-C4C4_CNOT4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd12438">
        <property type="entry name" value="RRM_CNOT4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.40.10:FF:000006">
        <property type="entry name" value="CCR4-NOT transcription complex subunit 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034261">
        <property type="entry name" value="CNOT4_RRM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039780">
        <property type="entry name" value="Mot2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039515">
        <property type="entry name" value="NOT4_mRING-HC-C4C4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003954">
        <property type="entry name" value="RRM_euk-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000571">
        <property type="entry name" value="Znf_CCCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12603">
        <property type="entry name" value="CCR4-NOT TRANSCRIPTION COMPLEX RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12603:SF0">
        <property type="entry name" value="CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14570">
        <property type="entry name" value="zf-RING_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00361">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50103">
        <property type="entry name" value="ZF_C3H1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6 10" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4 9" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 9" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="12">
        <location>
            <begin position="10"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="13">
        <location>
            <begin position="105"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="domain" description="C3H1-type" evidence="14">
        <location>
            <begin position="181"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="9">
        <location>
            <begin position="181"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="225"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="307"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="407"/>
            <end position="528"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="555"/>
            <end position="605"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="679"/>
            <end position="702"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="717"/>
            <end position="793"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="851"/>
            <end position="882"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="894"/>
            <end position="932"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1014"/>
            <end position="1089"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1106"/>
            <end position="1132"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1348"/>
            <end position="1375"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="10">
        <location>
            <begin position="1180"/>
            <end position="1234"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="254"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="307"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="322"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="11">
        <location>
            <begin position="428"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="565"/>
            <end position="583"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="593"/>
            <end position="605"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="679"/>
            <end position="700"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="720"/>
            <end position="737"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="11">
        <location>
            <begin position="853"/>
            <end position="865"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="11">
        <location>
            <begin position="871"/>
            <end position="881"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="922"/>
            <end position="932"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="1014"/>
            <end position="1033"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="1040"/>
            <end position="1053"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="1076"/>
            <end position="1089"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="1109"/>
            <end position="1119"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="OBZ82517.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="1375" mass="153157" checksum="41FAFEB252FA3639" modified="2016-11-30" version="1">MSSDEEDTDCPLCMEELDIADRNFRPCPCGYQICRFCWHHIKTNLNGRCPACRRLYTDQIVEFIPVSAEEIMRLKKEKKEKDRQTREMRDPSRRQLSNIRVVQKNLVYILGLGPKHASTDNDLFKKYGRIEKVVVSKRSITSSGAASVGIYVTYAKKEDAGKAIEGINGMEYDGKTIRASYGTTKYCTYYLRHMSCPNPNCMYLHEPGDDVDSYSKDASTTSATSTVAIGKHANTGSSSTSTASAFPNKRPATAATSVARNTNGASSPSMSTGAIISSATVAAAEVKPPRAWAPIPKVVPISPVVVSKEEQADSSSKEAAVKPSSSMKTTSTPKSTPAIDTSSSNSISTASSPTMATNSISVASKKPIRKSSLVPAKKVVPMEIDEKPALPASASWAKVQAPITVPAQSTTPDNFGPSLSDALNAPQKPKHSPSLKVKKEKKSKAKMVRIEEFEEAEREAKLAATSSPKPKASLVQPPSPVQSAISSKSDGVVSTKPTLPESETVVMPPTEKKITEESTLASQSDLPLAEHTLTTTGNTVEKQEDNTLILDEAQQTIDETEDLESMNKEEKLNEMPEMIEVKRTITSPQILNSDERVDQNEAEQEMHHLEERLDDDLTSLNESIIKAFDDAAAAAHSTDTGNTSLTPEASIQTEHNGDNVKEAAEDHSLLFHKPQEQMEERIEHADDTKIESEQQSKPEDLSSPLIAMDKLSALVEQELQHSSPAQQPHQLESSGQSIPGPFEPIPQEMKQHLPLENRMPPPGLGAPHHHAHSHMPPPPPPQGLPEWFNRGFDPFNGQDPSVIAARRLQHSQRMLEASGLFGGNHFNPNPHPPAVVNQFDFNLNPQFMIPSNHPHRPPHPHHLPHSHSTPPQAPPVPPPPMGMFMGNHLMMRSVPPPPDMLSPFHPQPHPHHTPPLHSSMVSPQQQQQSPYLSLRQQQLNPMDELRKEFNELQMNGVPHSPAFSSAPEQQSRDDLRALLPNVNISFNNFQEKVKAEEFYQKQLLIQRQQQKQQLHQRLSEQQQEQIPSPQSSSRDSLMMQDSPTSLSQSQQQQPDEKLLTSEKALIQSSPDVTAWRQDEQKDEQKDDPDVRVEAQNFFGEFLRKAASHQHQDVPSKIEEQPPAQPVSTASSLPFQDPAIMSIRLADGQNTSVNNRPNSENGITSSQNTILQILGGQSSPLMTTEQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHQYQQQQQQQQQQQQQFYFNQQMQHRQQQMDPRLNNNIIHQGFGFGNDLGTKPFSNAIASPPFQQQQQQQQSFNNAPRSSFMSGFREVPINMMNRMPPPPHHPGMMRAPIPPPLHPMGFQNNNYHAHHLHAQQQGPYSSHHPPPPPPPGIFADENRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-06-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N0B2</accession>
    <name>A0A1C7N0B2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_09873</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000960">
        <property type="protein sequence ID" value="OBZ82079.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N0B2"/>
    <dbReference type="InParanoid" id="A0A1C7N0B2"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="97"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ82079.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="97" mass="11396" checksum="707EC189C1DF212D" modified="2016-11-30" version="1" fragment="single">LSCLSKQDKSRIRHLKATVNKPVKPSRSNSGNNIYNFTSVNLSNVSTTNESKKRKIDFTNDDQSWPINSQEDIWEAWKQYLETQWPWIMVSTQLQKH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N0R9</accession>
    <name>A0A1C7N0R9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Transcription factor of morphogenesis MCM1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">MCM1_0</name>
        <name evidence="8" type="ORF">A0J61_09287</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000816">
        <property type="protein sequence ID" value="OBZ82663.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N0R9"/>
    <dbReference type="STRING" id="101091.A0A1C7N0R9"/>
    <dbReference type="InParanoid" id="A0A1C7N0R9"/>
    <dbReference type="OrthoDB" id="2284405at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000987">
        <property type="term" value="F:cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00266">
        <property type="entry name" value="MADS_SRF_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.1810.10:FF:000002">
        <property type="entry name" value="Serum response factor b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1810.10">
        <property type="entry name" value="Transcription factor, MADS-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050142">
        <property type="entry name" value="MADS-box/MEF2_TF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033897">
        <property type="entry name" value="SRF-like_MADS-box"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002100">
        <property type="entry name" value="TF_MADSbox"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036879">
        <property type="entry name" value="TF_MADSbox_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48019">
        <property type="entry name" value="SERUM RESPONSE FACTOR HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00319">
        <property type="entry name" value="SRF-TF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00404">
        <property type="entry name" value="MADSDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00432">
        <property type="entry name" value="MADS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55455">
        <property type="entry name" value="SRF-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00350">
        <property type="entry name" value="MADS_BOX_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50066">
        <property type="entry name" value="MADS_BOX_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="MADS-box" evidence="7">
        <location>
            <begin position="37"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="117"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="19"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="122"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="144"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="6">
        <location>
            <begin position="164"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="174"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="188"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="225"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="267"/>
            <end position="278"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50066"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OBZ82663.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="315" mass="34915" checksum="675B5F936BEFF3CA" modified="2016-11-30" version="1">MNHNQLPTEDPLIKKVKMDDDDNDSGDDSDVKPSRRSGRRKIKIEYIEDKNRRHITFSKRKAGIMKKAYELSTLTGTQVLLLVVSETGLVYTFTTVKLQPIVTKPEGKNLIQACLNAPDPMSNEQADNESTYNPGNNTGGSSRADVDKKPVYEDSKLETVPQASAPPPPPPSQSTPNAYNNPGPAGNSASPYQPSYGSGSATSSMPPMVPNTYNGHPSYMSHPYHSQQQQQQQQQQQQSQPPSNQPNHSPQQQPYGQLPAPAFYGNQQQPPYMAHQQQAPPPQQHHGYWSNNSASPIMRQPQEDEKVRRGLPPKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N158</accession>
    <name>A0A1C7N158_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Endonuclease/exonuclease/phosphatase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_10611</name>
        <name evidence="2" type="ORF">A0J61_10857</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001451">
        <property type="protein sequence ID" value="OBZ81094.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="LUGH01001269">
        <property type="protein sequence ID" value="OBZ81340.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N158"/>
    <dbReference type="STRING" id="101091.A0A1C7N158"/>
    <dbReference type="InParanoid" id="A0A1C7N158"/>
    <dbReference type="OrthoDB" id="2208330at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.10.10">
        <property type="entry name" value="Endonuclease/exonuclease/phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036691">
        <property type="entry name" value="Endo/exonu/phosph_ase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005135">
        <property type="entry name" value="Endo/exonuclease/phosphatase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03372">
        <property type="entry name" value="Exo_endo_phos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56219">
        <property type="entry name" value="DNase I-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Endonuclease/exonuclease/phosphatase" evidence="1">
        <location>
            <begin position="52"/>
            <end position="245"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03372"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ81094.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ81340.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="383" mass="43525" checksum="E3AE20020281A425" modified="2016-11-30" version="1">MYRTWKTCLLHILDVSHAKIRLCMVPKYTSVLDVRCAHLDVHQTHPVCRGVRYIRTLSLDIIALQETYAVSTDLASQFHMQFQAVDSIWTPHCGLVPFSPDLFFSQIVKSPCGRLITAIVSHKSDLFEPLSVSVLYAPVCCKERYPFLQDLIHSLPSSPILQAQPLRHILLGDFNYSISSGINVRFRRSKAPTSWLNHVDRFYADAVTPRKQAAHATFSGGLSQSCIDYSYVSKDLYPARTYGSVFYINPAWTDHFMVKTCLQLVPSSVSNSLNQTGKGLWRAHPGLAKDPVFCEQLASALSQTVASFPDWYYPTLQWESLKTTTRSVAQLYSRKKAFSLKKAEQTLQVKRRILLKLIDHHPDRTKDVSSHLRVIEGKLQQLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-06-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N178</accession>
    <name>A0A1C7N178_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_09573</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000881">
        <property type="protein sequence ID" value="OBZ82379.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N178"/>
    <dbReference type="InParanoid" id="A0A1C7N178"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ82379.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="230" mass="26047" checksum="6760BF655BDBC2DF" modified="2016-11-30" version="1">MLTNAYSNFETAQGVQCNSNGHVEQSIGTTTVVEASESASDIDLVDFSVYTFNFTIQRVKQGFVQDGVQFVQQCCSQQASWNVDGIAKRIFEGQWRRFRFPATVAIFLKRDAVVTTCTSSNQNLTNAICKPKKMTKKCTGTVYKYDGFADKNTKWRNRQTAAGYLTDLHDASGFSQFKAYPTDSQPFVHLDKYHLLLTLNIDWFQHSDVIYNAKCIHMTIQNLSKKATEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N1W4</accession>
    <name>A0A1C7N1W4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_08957</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000743">
        <property type="protein sequence ID" value="OBZ82991.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N1W4"/>
    <dbReference type="STRING" id="101091.A0A1C7N1W4"/>
    <dbReference type="InParanoid" id="A0A1C7N1W4"/>
    <dbReference type="OrthoDB" id="2282872at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ82991.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="144" mass="16620" checksum="CD5B58E736264C72" modified="2016-11-30" version="1">MRTIALSNGLYFPENHHAIYSNLCGLKGLHGQFRSKGTMVNAPVNVDTYASSLPRNLDDNSTVHVHLARKTIYLRDYMQRFIKPDYMWTAVRYLQGIFLHIDHDIDIITRNLNQNNEGFKSTEINEGELDVLFEEKFSPGDDDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N274</accession>
    <name>A0A1C7N274_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_08850</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000722">
        <property type="protein sequence ID" value="OBZ83101.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N274"/>
    <dbReference type="FunCoup" id="A0A1C7N274">
        <property type="interactions" value="10"/>
    </dbReference>
    <dbReference type="InParanoid" id="A0A1C7N274"/>
    <dbReference type="OrthoDB" id="10034502at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013744">
        <property type="entry name" value="SidJ"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31591">
        <property type="entry name" value="UPF0613 PROTEIN PB24D3.06C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31591:SF1">
        <property type="entry name" value="UPF0613 PROTEIN PB24D3.06C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08538">
        <property type="entry name" value="DUF1749"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ83101.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="278" mass="31881" checksum="0CB2C61B9CD5783E" modified="2016-11-30" version="1">MNFTGQLFTYDEENRLTAFETGPIESGKVVVFIGGLGDGYNAVPFIPLLAETLDKLGWSLIQVQLQSSYDGYGTSNLQNDICQLDSLVSYLLKEKQKKKIVFIGHSTGSQDCYWHNKSGQYNQSISGYVLQAPVSDREHFSKNLDNFEHHLKLATQLRDEGKGQELLPRDTFWAPITADRFYSFGTRLGDDDVFSTDFTDEEIKGLYKDIHRPICWVYSENDEFYASEKDKRQVMERFKSLCPAIVETHIVPQGDHNITRTDSQQAFCQIIHDFLKQF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N319</accession>
    <name>A0A1C7N319_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Transcriptional regulator prz1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">prz1_1</name>
        <name evidence="10" type="ORF">A0J61_08487</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000659">
        <property type="protein sequence ID" value="OBZ83461.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N319"/>
    <dbReference type="STRING" id="101091.A0A1C7N319"/>
    <dbReference type="InParanoid" id="A0A1C7N319"/>
    <dbReference type="OrthoDB" id="8117402at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000125">
        <property type="entry name" value="Putative zinc finger protein 143"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000100">
        <property type="entry name" value="Zinc finger 45-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000145">
        <property type="entry name" value="Zinc finger protein 574"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23235">
        <property type="entry name" value="KRUEPPEL-LIKE TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23235:SF120">
        <property type="entry name" value="KRUPPEL-LIKE FACTOR 15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 7" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="9">
        <location>
            <begin position="317"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="9">
        <location>
            <begin position="347"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="9">
        <location>
            <begin position="375"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="275"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="276"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="290"/>
            <end position="304"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OBZ83461.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="460" mass="50763" checksum="45E07FE1AC79DEBC" modified="2016-11-30" version="1">MMHYQGQPNNFWGEDDIELFQNLSEVAAMPSSYNAALQNMNNSGINNYFDHNQVASVPLIAPLMASQTDLSHAVSRMNMEDLYEKPTTQARPRDSIASTLSLEIQPCISITEPTPVQHQPPAALNFVDQFISEHSMPYSQTQQPVDNNAFNQSIESTFVLEDLLMTQNGSVDWLSWTPANGSPISVGSNTFEDQFSNYSNSSQEFYDHTLMPASGDFVPSHYSVGHPSPSSLQEFNIDMSPTFSTNLTVKKPSRARRVSEPPKLSDSFQELLQQIQPSQPVSSSSVSAKAPERPIRRSHSDSRRARSNSSVSAAGVHVCTHPGCGKSFTRPYNLTSHMRTHTADRPFACSQCGRKFARQHDRNRHEKLHWGIKPYACMHCNKPFARMDALNRHLRVENGCQQQANLAAAAATAANTTTATNSAAANTTFTTTSNMTANDILAQMTNTAISNPIAVQTFIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N3C2</accession>
    <name>A0A1C7N3C2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Mitotic spindle-associated MMXD complex subunit MIP18</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">Fam96b</name>
        <name evidence="4" type="ORF">A0J61_08420</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the MIP18 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000646">
        <property type="protein sequence ID" value="OBZ83527.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N3C2"/>
    <dbReference type="FunCoup" id="A0A1C7N3C2">
        <property type="interactions" value="331"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N3C2"/>
    <dbReference type="InParanoid" id="A0A1C7N3C2"/>
    <dbReference type="OrthoDB" id="2746at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097361">
        <property type="term" value="C:cytosolic [4Fe-4S] assembly targeting complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007059">
        <property type="term" value="P:chromosome segregation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016226">
        <property type="term" value="P:iron-sulfur cluster assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051604">
        <property type="term" value="P:protein maturation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.300.130:FF:000005">
        <property type="entry name" value="Mitotic spindle-associated mmxd complex subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.1280">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.130">
        <property type="entry name" value="Fe-S cluster assembly (FSCA)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034904">
        <property type="entry name" value="FSCA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039796">
        <property type="entry name" value="MIP18"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002744">
        <property type="entry name" value="MIP18-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12377:SF0">
        <property type="entry name" value="CYTOSOLIC IRON-SULFUR ASSEMBLY COMPONENT 2B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12377">
        <property type="entry name" value="CYTOSOLIC IRON-SULFUR ASSEMBLY COMPONENT 2B-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01883">
        <property type="entry name" value="FeS_assembly_P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117916">
        <property type="entry name" value="Fe-S cluster assembly (FSCA) domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0159">Chromosome partition</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MIP18 family-like" evidence="3">
        <location>
            <begin position="38"/>
            <end position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010381"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OBZ83527.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="166" mass="18635" checksum="898180AFA5D32113" modified="2016-11-30" version="1">MAQNLINANPTVYNTKTLIRKETEAELDDDIEDPIDAQEVFDLIRSISDPEHPLTLEQLNVTQFEHIQVDNQSSKILIEFTPTIPHCSMATLIGLCIRVRLLRSLPDRFKVDIRVRKGTHQSEGAVNKQLNDKERVAAALENNHLLEVVNQCLATASLRGTEVAAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N3K5</accession>
    <name>A0A1C7N3K5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">tRNA-uridine aminocarboxypropyltransferase 1</fullName>
            <ecNumber evidence="2">2.5.1.25</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">DTW domain-containing protein 1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="primary">dtwd1</name>
        <name evidence="13" type="ORF">A0J61_08729</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes the formation of 3-(3-amino-3-carboxypropyl)uridine (acp3U) at position 20 in the D-loop of several cytoplasmic tRNAs (acp3U(20)).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>a uridine in tRNA + S-adenosyl-L-methionine = a 3-[(3S)-3-amino-3-carboxypropyl]uridine in tRNA + S-methyl-5'-thioadenosine + H(+)</text>
            <dbReference type="Rhea" id="RHEA:62432"/>
            <dbReference type="Rhea" id="RHEA-COMP:13339"/>
            <dbReference type="Rhea" id="RHEA-COMP:16092"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17509"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="ChEBI" id="CHEBI:82930"/>
            <dbReference type="EC" id="2.5.1.25"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the TDD superfamily. DTWD1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.25" evidence="2"/>
    <dbReference type="EMBL" id="LUGH01000700">
        <property type="protein sequence ID" value="OBZ83219.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N3K5"/>
    <dbReference type="InParanoid" id="A0A1C7N3K5"/>
    <dbReference type="OrthoDB" id="660555at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016432">
        <property type="term" value="F:tRNA-uridine aminocarboxypropyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008033">
        <property type="term" value="P:tRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005636">
        <property type="entry name" value="DTW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051521">
        <property type="entry name" value="tRNA_Mod/Golgi_Maint"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15627">
        <property type="entry name" value="NATURAL KILLER CELL-SPECIFIC ANTIGEN KLIP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15627:SF8">
        <property type="entry name" value="TRNA-URIDINE AMINOCARBOXYPROPYLTRANSFERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03942">
        <property type="entry name" value="DTW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01144">
        <property type="entry name" value="DTW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="5" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="DTW" evidence="12">
        <location>
            <begin position="49"/>
            <end position="232"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012386"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00037050"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00038290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00039242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00042508"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00048718"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM01144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="OBZ83219.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="259" mass="30490" checksum="E20B0AF5567A76E2" modified="2016-11-30" version="1">MSMSQEENKKRSFDKANAEGPFDQFKIDDDQVLHKIEKRSVCPGCNKTVKYFCYKCLAIVGMEASSVPHVDLPVHLDIIKHNKELDGKSTAVHACIIAKGNVDLHTWPQVPELEQPERTLLLFPSPGAKRLEDIPRDSFDRIAVIDGTWIQAKQIANNTPVLKKMQHVTIQPQKTHFWRFQNVDDQHLATIEAIYYLYREYGQTYEPPYRGQYDNLLFYYKFFYHLIQNTYQTTKRTATFSHRHQQKDYIKYKEEKEEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N3X4</accession>
    <name>A0A1C7N3X4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Alpha-1,3/1,6-mannosyltransferase ALG2</fullName>
            <ecNumber evidence="12">2.4.1.132</ecNumber>
            <ecNumber evidence="12">2.4.1.257</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12">GDP-Man:Man(1)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="15" type="primary">ALG2</name>
        <name evidence="15" type="ORF">A0J61_08596</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 12">Mannosylates Man(2)GlcNAc(2)-dolichol diphosphate and Man(1)GlcNAc(2)-dolichol diphosphate to form Man(3)GlcNAc(2)-dolichol diphosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10 12">
            <text>a beta-D-Man-(1-&gt;4)-beta-D-GlcNAc-(1-&gt;4)-alpha-D-GlcNAc-diphospho-di-trans,poly-cis-dolichol + GDP-alpha-D-mannose = an alpha-D-Man-(1-&gt;3)-beta-D-Man-(1-&gt;4)-beta-D-GlcNAc-(1-&gt;4)-alpha-D-GlcNAc-diphospho-di-trans,poly-cis-dolichol + GDP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:29515"/>
            <dbReference type="Rhea" id="RHEA-COMP:19511"/>
            <dbReference type="Rhea" id="RHEA-COMP:19513"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57527"/>
            <dbReference type="ChEBI" id="CHEBI:58189"/>
            <dbReference type="ChEBI" id="CHEBI:58472"/>
            <dbReference type="ChEBI" id="CHEBI:132510"/>
            <dbReference type="EC" id="2.4.1.132"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="10 12">
            <dbReference type="Rhea" id="RHEA:29516"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11 12">
            <text>an alpha-D-Man-(1-&gt;3)-beta-D-Man-(1-&gt;4)-beta-D-GlcNAc-(1-&gt;4)-alpha-D-GlcNAc-diphospho-di-trans,poly-cis-dolichol + GDP-alpha-D-mannose = an alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;6)]-beta-D-Man-(1-&gt;4)-beta-D-GlcNAc-(1-&gt;4)-alpha-D-GlcNAc-diphospho-di-trans,poly-cis-dolichol + GDP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:29519"/>
            <dbReference type="Rhea" id="RHEA-COMP:19513"/>
            <dbReference type="Rhea" id="RHEA-COMP:19515"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57527"/>
            <dbReference type="ChEBI" id="CHEBI:58189"/>
            <dbReference type="ChEBI" id="CHEBI:132510"/>
            <dbReference type="ChEBI" id="CHEBI:132511"/>
            <dbReference type="EC" id="2.4.1.257"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="11 12">
            <dbReference type="Rhea" id="RHEA:29520"/>
        </physiologicalReaction>
    </comment>
    <comment type="pathway">
        <text evidence="3 12">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 12">Endoplasmic reticulum membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="12">Belongs to the glycosyltransferase group 1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.132" evidence="12"/>
    <dbReference type="EC" id="2.4.1.257" evidence="12"/>
    <dbReference type="EMBL" id="LUGH01000678">
        <property type="protein sequence ID" value="OBZ83356.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N3X4"/>
    <dbReference type="FunCoup" id="A0A1C7N3X4">
        <property type="interactions" value="505"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N3X4"/>
    <dbReference type="InParanoid" id="A0A1C7N3X4"/>
    <dbReference type="OrthoDB" id="448893at2759"/>
    <dbReference type="UniPathway" id="UPA00378"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004378">
        <property type="term" value="F:GDP-Man:Man(1)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102704">
        <property type="term" value="F:GDP-Man:Man(2)GlcNAc(2)-PP-Dol alpha-1,6-mannosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033164">
        <property type="term" value="F:initiation-specific glycolipid 1,6-alpha-mannosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006488">
        <property type="term" value="P:dolichol-linked oligosaccharide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd03805">
        <property type="entry name" value="GT4_ALG2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2000">
        <property type="entry name" value="Glycogen Phosphorylase B"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027054">
        <property type="entry name" value="ALG2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001296">
        <property type="entry name" value="Glyco_trans_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028098">
        <property type="entry name" value="Glyco_trans_4-like_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45918">
        <property type="entry name" value="ALPHA-1,3/1,6-MANNOSYLTRANSFERASE ALG2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45918:SF1">
        <property type="entry name" value="ALPHA-1,3_1,6-MANNOSYLTRANSFERASE ALG2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13439">
        <property type="entry name" value="Glyco_transf_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00534">
        <property type="entry name" value="Glycos_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53756">
        <property type="entry name" value="UDP-Glycosyltransferase/glycogen phosphorylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 12" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="4 12 15" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 12 15" id="KW-0808">Transferase</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="Glycosyltransferase subfamily 4-like N-terminal" evidence="14">
        <location>
            <begin position="20"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyl transferase family 1" evidence="13">
        <location>
            <begin position="213"/>
            <end position="401"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003142"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004586"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00045103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00045104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU367136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF00534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF13439"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="OBZ83356.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="457" mass="51845" checksum="00D57A68C93DEF1C" modified="2016-11-30" version="1">MSEQKDAKLSIAFIHPDLGIGGAERLVVDAAVGIQSKGHQVVMYTSHHDRNHCFEETRDGTLQVRVHGDWLPRHVLGRCHIIFAILRQFVLVLWLLQHEKDTYDIIMVDQLSACVPLLKWFSTARVLFYCHFPDKLLTNRDSTLKQLYRVPIDKLEEWSTGMADAITVNSQFTGGMFRRSFPGILKKPRVLYPPINFAAYDKQVDLSDPSVQQIESHHQTIVSINRFEKKKNVELALNAFALLGNMIPPEEFKKYRLVLAGGYDKRVKENVDYLRFLDTMAKETYGLETCTLFPSSDNRPPATAQVVFLCSFNDAQRTYLLHASFLMLYTPSNEHFGITPVEGMYAGVPVIAANSGGPLETVKDKETGLILAPEPQLWAEGIHAFITQKYNSQEMGQAGRRHVQAKFSLEAFADQLEDVCEEIASGGRPTRHAYDNVEYTVRIIVAIGIFVIWYKFC</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-06-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N4M2</accession>
    <name>A0A1C7N4M2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_07946</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000570">
        <property type="protein sequence ID" value="OBZ84001.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N4M2"/>
    <dbReference type="InParanoid" id="A0A1C7N4M2"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ84001.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="72" mass="8130" checksum="5AC12D2731329F37" modified="2016-11-30" version="1">MTSSDFYVAKELNTLPKGEQTGPVNIYSEKVSSKKIERGIDFQVKADGAVILKSPPRREIRKQPESITIYFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N5C8</accession>
    <name>A0A1C7N5C8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">54S ribosomal protein L23, mitochondrial</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">MRPL23</name>
        <name evidence="5" type="ORF">A0J61_08085</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the universal ribosomal protein uL13 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000592">
        <property type="protein sequence ID" value="OBZ83866.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N5C8"/>
    <dbReference type="FunCoup" id="A0A1C7N5C8">
        <property type="interactions" value="356"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N5C8"/>
    <dbReference type="InParanoid" id="A0A1C7N5C8"/>
    <dbReference type="OrthoDB" id="274622at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005762">
        <property type="term" value="C:mitochondrial large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017148">
        <property type="term" value="P:negative regulation of translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00392">
        <property type="entry name" value="Ribosomal_L13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1180.10">
        <property type="entry name" value="Ribosomal protein L13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01366">
        <property type="entry name" value="Ribosomal_uL13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005822">
        <property type="entry name" value="Ribosomal_uL13"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005823">
        <property type="entry name" value="Ribosomal_uL13_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023563">
        <property type="entry name" value="Ribosomal_uL13_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036899">
        <property type="entry name" value="Ribosomal_uL13_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01066">
        <property type="entry name" value="rplM_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11545:SF2">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN UL13M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11545">
        <property type="entry name" value="RIBOSOMAL PROTEIN L13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00572">
        <property type="entry name" value="Ribosomal_L13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002181">
        <property type="entry name" value="Ribosomal_L13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52161">
        <property type="entry name" value="Ribosomal protein L13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00783">
        <property type="entry name" value="RIBOSOMAL_L13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 5" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006227"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003877"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OBZ83866.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="143" mass="16061" checksum="32C9E2FE985318FD" modified="2016-11-30" version="1">MSQAVGNTALAYARVWHVVDAKQRVLGRLATNVATTLMGKHKPIYDPAADCGDYVVVINAKDILVSGKKAEQKLYRHHTMHPGGLKEITFEKLQQKDPAEPIRKAVSGMLPKNRLRQVRLDRLKIFEGSEHPYKSNIIKQHGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N5Q5</accession>
    <name>A0A1C7N5Q5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">AP-3 complex subunit delta</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Adaptor-related protein complex 3 subunit delta</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">Delta-adaptin 3</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="primary">Ap3d1</name>
        <name evidence="13" type="ORF">A0J61_07479</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasmic vesicle</location>
            <location evidence="1">Clathrin-coated vesicle membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
            <orientation evidence="1">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the adaptor complexes large subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000506">
        <property type="protein sequence ID" value="OBZ84472.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N5Q5"/>
    <dbReference type="FunCoup" id="A0A1C7N5Q5">
        <property type="interactions" value="408"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N5Q5"/>
    <dbReference type="InParanoid" id="A0A1C7N5Q5"/>
    <dbReference type="OrthoDB" id="10264595at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030123">
        <property type="term" value="C:AP-3 adaptor complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030665">
        <property type="term" value="C:clathrin-coated vesicle membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010008">
        <property type="term" value="C:endosome membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006896">
        <property type="term" value="P:Golgi to vacuole transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006623">
        <property type="term" value="P:protein targeting to vacuole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.10.10:FF:000251">
        <property type="entry name" value="AP-3 complex subunit delta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017105">
        <property type="entry name" value="AP3_complex_dsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002553">
        <property type="entry name" value="Clathrin/coatomer_adapt-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058898">
        <property type="entry name" value="Mu_AP3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22781:SF12">
        <property type="entry name" value="AP-3 COMPLEX SUBUNIT DELTA-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22781">
        <property type="entry name" value="DELTA ADAPTIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01602">
        <property type="entry name" value="Adaptin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26171">
        <property type="entry name" value="Mu_AP3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Clathrin/coatomer adaptor adaptin-like N-terminal" evidence="11">
        <location>
            <begin position="20"/>
            <end position="584"/>
        </location>
    </feature>
    <feature type="domain" description="AP-3 complex subunit delta Mu C-terminal" evidence="12">
        <location>
            <begin position="1099"/>
            <end position="1173"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="651"/>
            <end position="693"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="737"/>
            <end position="832"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="844"/>
            <end position="908"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="10">
        <location>
            <begin position="660"/>
            <end position="674"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="10">
        <location>
            <begin position="742"/>
            <end position="751"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="757"/>
            <end position="772"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="783"/>
            <end position="793"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="799"/>
            <end position="809"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="844"/>
            <end position="861"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00015717"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00076742"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00083145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF01602"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF26171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="OBZ84472.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="1176" mass="133145" checksum="705A2DBB413696D5" modified="2016-11-30" version="1">MFEKSLTDLIRGIRANKKNEQKYITACLQEIRNEVKSNDLDIKSNAVAKLAYLHMLGYDMSWASFHMVEVMSSAKFIHKRTGYLAATLSFQQDTDVLMLTTNLIKKDLASPNVVDMGTALNGLSHIVTPDLARDLSPDLVSMLNHSRPYIRKKVVLVLYKIFLKYPEALRLSFARLKEKLEDPDPSVVSAAVSVICELARKNPKNYLSLAPQLFKLLTTSSNNWMLIKIIKLFASLTPLEPRLIKKLLPPLTSLIQTTPAMSLLYECIYTVITGGFLEAAGDAGNALAATCTNKLRRFLEDPDQNLKYVGLLAMGRLLSTHPKLVAEHKDIILECIDDEDISIRLRALDLVVGMVNRKNIVDIVKRLITHIMPQNDSLEPESLHHSSTIFDPAYRTDIINRIIFMCSQNRYHFINDFEWYLSVLVDITYAAGVNVGEILTDQLMDVSVRVKSVREYAVKQMYHLLQDKQFLETAKKRDANIEVLSAAAWICGEYCNYLEDIPSTLECMLLPQVAKLSTKVQTIYVHSVIKIFAYWTTELIPQWNAELQHEFLKVTQVMHDKMTMFVHSSDLEVQERALDVKSLFALVLNAVENTEDQVPSILEGLPELFFIYELNPVAPKAQTKVPVPEGLDLDAWINKPLPDLIQDLDSDETEEPKHLSAQKKHKKKKSGKSSRKYEASEDEEEKEKRRIARREARKNDPYYIGEDKHRKLLELDDSDIDSIPVVELSVDDIKKSVEAKKASKRSAKKPAVRPVYAEEEMPEDAVASDEEPTTEKRKKNKKKSEVYAKKSAHDIFANNEESGLNSVDLNTPLGEDENFQAPQTYLSPEELRLKEEARYRAERKELKALQKKNKEAVESKKKSSKSSSVDPTQPEKKKKKKKSSSSNKKSAKQKQEEEEQKLAEEDLTLNTEQVKEAIGYEESHFKPIQVFSDDHISLVATMKLLDSKEDLPVIAIHFTMENKNEETMLPSAHMEFAQSFDLTSVENTDTNIASATEHFELQAKEKVESEAHFKLNSNARKDICLRGDLFYDIDGSSALQQFDFEVPVPTSLLLTHDPDMDPNTFASMLAERGSEFEYHEHVTIDIPLPKEEESMQEAIVRAFEVITRTSGLAVVEVIAGAASLYGKSVQGDQVAGLLKCNIQPEQALASLDIDLKSTEEGLLEGLVHELKQIQMV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N5R9</accession>
    <name>A0A1C7N5R9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_09256</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000809">
        <property type="protein sequence ID" value="OBZ82694.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N5R9"/>
    <dbReference type="InParanoid" id="A0A1C7N5R9"/>
    <dbReference type="OrthoDB" id="2277358at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ82694.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="525" mass="61763" checksum="C3D190C8813BE792" modified="2016-11-30" version="1">MDISKKYEDYKLECDVEKTSLNYFKENSAKEWCFKSYLNKAHPEIRKYKRKNINYIYFCYLDDLKWIEDNKSLPREIRNYALNLKRDKLSTEELEKCTFPKPSDHQPIYTMHVSNNNCDVKIATNQEIYYCSNSRSTKRKLNKNEEKDRTKRTNIEDTDEDELTKKWKLFLEKAKHNPLIHKYSPAKNDIICCGEGISNKPSYPEDIYREYKQKHPEKKACFIDKKFIKYIDRVIDSSSIKQYKRNVQSTKELGDGELEEQAEFLNDFFLATYHMYQSLATPFHSESVFTYCLILPYLEMIAFHLSEIGDLKAACLPGEETLLSMSKCLKEKNGHFVYLADGVLRLQNLHDVELLLLEVSGTFLNTDMSKINFDHHKGMFGTLSMLKNIAKQFKYGDIKLFEKIKLFFLQGAGNRLRCWSVVYTDDVSHMWLEDTLLLKYDFEDKEEFLPRALNFFLNLKNNIQETLVALKELKESHKDNLRQSRYDISPSLLTDVVKPTIVRLTQSEHAKNMSSVGPFESSDTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N629</accession>
    <name>A0A1C7N629_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Protein GET1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7 9" type="primary">GET1</name>
        <name evidence="9" type="ORF">A0J61_07478</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the WRB/GET1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000506">
        <property type="protein sequence ID" value="OBZ84471.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N629"/>
    <dbReference type="FunCoup" id="A0A1C7N629">
        <property type="interactions" value="260"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N629"/>
    <dbReference type="InParanoid" id="A0A1C7N629"/>
    <dbReference type="OrthoDB" id="69461at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043529">
        <property type="term" value="C:GET complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043495">
        <property type="term" value="F:protein-membrane adaptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071816">
        <property type="term" value="P:tail-anchored membrane protein insertion into ER membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.660">
        <property type="entry name" value="Helix hairpin bin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03113">
        <property type="entry name" value="Get1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028945">
        <property type="entry name" value="Get1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027538">
        <property type="entry name" value="Get1_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029012">
        <property type="entry name" value="Helix_hairpin_bin_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42650:SF1">
        <property type="entry name" value="GUIDED ENTRY OF TAIL-ANCHORED PROTEINS FACTOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42650">
        <property type="entry name" value="TAIL-ANCHORED PROTEIN INSERTION RECEPTOR WRB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04420">
        <property type="entry name" value="CHD5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="6 7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="7" id="KW-0813">Transport</keyword>
    <feature type="topological domain" description="Lumenal" evidence="7">
        <location>
            <begin position="1"/>
            <end position="3"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="105"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="142"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="topological domain" description="Cytoplasmic" evidence="7">
        <location>
            <begin position="169"/>
            <end position="190"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010799"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OBZ84471.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="190" mass="21780" checksum="7C8058372DE8932B" modified="2016-11-30" version="1">MYLPITIFLLVLVTESILFLGYSYVTSLAYELYVKITKDARFIKQQKMKRDALKLKAELAQTSSQDEFAKWAKLRRKLDKSVADLEKLGSEITYSKTAFELKVKSVLWFLVHGSQFVMVMWFRKNAVFYLPPGWFGPAQRFLSWPFAPAGSVSVAVWFAACRRMIKSVALVVNDFVFIPAAEKKVKASQN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-06-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N671</accession>
    <name>A0A1C7N671_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_07326</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000487">
        <property type="protein sequence ID" value="OBZ84632.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N671"/>
    <dbReference type="InParanoid" id="A0A1C7N671"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ84632.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="59" mass="6984" checksum="B44AD0B6BABCF7BB" modified="2016-11-30" version="1">MYAKDDDLTIFQNEPIMIALNDDSSRTKGRQETERLIMKYVCLMGFSYIRESNNQQYVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N674</accession>
    <name>A0A1C7N674_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">GDT1 family protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">GDT1</name>
        <name evidence="8" type="ORF">A0J61_07421</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Membrane</location>
            <topology evidence="1 6">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the GDT1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000500">
        <property type="protein sequence ID" value="OBZ84521.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N674"/>
    <dbReference type="FunCoup" id="A0A1C7N674">
        <property type="interactions" value="497"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N674"/>
    <dbReference type="InParanoid" id="A0A1C7N674"/>
    <dbReference type="OrthoDB" id="442680at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005801">
        <property type="term" value="C:cis-Golgi network"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000329">
        <property type="term" value="C:fungal-type vacuole membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005797">
        <property type="term" value="C:Golgi medial cisterna"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015369">
        <property type="term" value="F:calcium:proton antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010486">
        <property type="term" value="F:manganese:proton antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032468">
        <property type="term" value="P:Golgi calcium ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032472">
        <property type="term" value="P:Golgi calcium ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030026">
        <property type="term" value="P:intracellular manganese ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001727">
        <property type="entry name" value="GDT1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049555">
        <property type="entry name" value="GDT1-like_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12608:SF1">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 165"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12608">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN HTP-1 RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01169">
        <property type="entry name" value="GDT1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01214">
        <property type="entry name" value="UPF0016"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008889502" description="GDT1 family protein" evidence="6">
        <location>
            <begin position="23"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="62"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="92"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="124"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="201"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="242"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="275"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="149"/>
            <end position="176"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU365102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OBZ84521.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="303" mass="33118" checksum="7C453E975D2D3356" modified="2016-11-30" version="1">MTYSQKLALVSSLLLLITLVKAQLDNPAEEILDATNEPPIMDTTLDTTDLVLGQDGVVEKSFVISLLMIIVSEIGDKTFLIAAIMAMKHSRLVVFAAAFSSLLIMSVLSAFLGHVVPNLIPKQYTDICAALLFLCFGLRMMYEAYHMDEAAGNEEMQEVEEELKTVEDREHANKLEELEVGGLENAAHAPTSQAEKAKEGLMNLMQLVFSPVFVQTFVLTFLGEWGDRSQISTIALAAANNVYYVTAGVVFGHAMCTALAVMGGRMLASKISVKTVTFAGSVLFLIFGVFYGFNAYKSLQEFN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N6C3</accession>
    <name>A0A1C7N6C3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Transcription factor tau subunit sfc1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">sfc1</name>
        <name evidence="8" type="ORF">A0J61_07252</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000480">
        <property type="protein sequence ID" value="OBZ84692.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N6C3"/>
    <dbReference type="FunCoup" id="A0A1C7N6C3">
        <property type="interactions" value="439"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N6C3"/>
    <dbReference type="InParanoid" id="A0A1C7N6C3"/>
    <dbReference type="OrthoDB" id="5598268at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000127">
        <property type="term" value="C:transcription factor TFIIIC complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001002">
        <property type="term" value="F:RNA polymerase III type 1 promoter sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001003">
        <property type="term" value="F:RNA polymerase III type 2 promoter sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006384">
        <property type="term" value="P:transcription initiation at RNA polymerase III promoter"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.160">
        <property type="entry name" value="TFIIIC, subcomplex tauA, subunit Sfc1, barrel domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019136">
        <property type="entry name" value="TF_IIIC_su-5_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040454">
        <property type="entry name" value="TF_IIIC_Tfc1/Sfc1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041499">
        <property type="entry name" value="Tfc1/Sfc1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042536">
        <property type="entry name" value="TFIIIC_tauA_Sfc1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13230:SF5">
        <property type="entry name" value="GENERAL TRANSCRIPTION FACTOR 3C POLYPEPTIDE 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13230">
        <property type="entry name" value="GENERAL TRANSCRIPTION FACTOR IIIC, POLYPEPTIDE 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09734">
        <property type="entry name" value="Tau95"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17682">
        <property type="entry name" value="Tau95_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <feature type="domain" description="Transcription factor IIIC subunit Tfc1/Sfc1 triple barrel" evidence="7">
        <location>
            <begin position="19"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="domain" description="Transcription factor IIIC subunit 5 HTH" evidence="6">
        <location>
            <begin position="164"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="491"/>
            <end position="537"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="497"/>
            <end position="524"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF09734"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF17682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OBZ84692.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="537" mass="62683" checksum="F6D6FE59DABCD805" modified="2016-11-30" version="1">MSNYDPAPILPIGPKKFFCVEFPGHVKRPERAIKMMGGQKAIADAIVNTSVVELRYRDTNTFAHPIKGDIVPTSKLLVKVTRRVKKKKQQQEEEEEEEEGPYTIEMMGTVSKTLRFRALADFQYHVPSDDRIRQLKEALMKGSLNRIIDFRVDLDEKEAELKQIPPPAFTPLENIFKYNYRQNAPVLRVRVRQPDGSFQVKLINKAKHAYNHITGINYEEENVPTKSWHTLVPPADGGPKETWETVCKLYQERPIWSRFALKNALDVKYHRYLRDSLVQVAYTFHSGPWRDCWVKYGLDPRQDPSCHIYQQVDIRKMFNLQSTDRPYKHIKRIKPDLGTSITKPEPVEVPEVPFNQNHIFDGQRVPGATSLYQLCDIIDPDITPLIRHPEYRKANCSKFSGYYYQCVFERIRRYVRAKHFSLLDDGVAEAIEDSEKGIMEEIQKEIDRDRQLEEEEEMDLMAKEKAVTEAMEINQSAQPLKEIADRYIEELGQNKDFDDEEVEIDALEEYDEWDEDAEMQDTETQDVGTQDVEMKED</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2024-01-24" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N6E3</accession>
    <name>A0A1C7N6E3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_07226</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000477">
        <property type="protein sequence ID" value="OBZ84725.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N6E3"/>
    <dbReference type="STRING" id="101091.A0A1C7N6E3"/>
    <dbReference type="InParanoid" id="A0A1C7N6E3"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ84725.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="75" mass="8960" checksum="A6ACE971FCDE4F38" modified="2016-11-30" version="1" fragment="single">MINVSWIAPYISYLPKNYKTHINIECCQVIQDMKIEKLLQGRYIDPTEAFSYIFEYKVHKEDLIVTILDCYLPNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N8H1</accession>
    <name>A0A1C7N8H1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">P-loop containing nucleoside triphosphate hydrolase protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_06590</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000405">
        <property type="protein sequence ID" value="OBZ85357.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N8H1"/>
    <dbReference type="STRING" id="101091.A0A1C7N8H1"/>
    <dbReference type="InParanoid" id="A0A1C7N8H1"/>
    <dbReference type="OrthoDB" id="408152at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040632">
        <property type="entry name" value="Sulfotransfer_4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36978:SF4">
        <property type="entry name" value="P-LOOP CONTAINING NUCLEOSIDE TRIPHOSPHATE HYDROLASE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36978">
        <property type="entry name" value="P-LOOP CONTAINING NUCLEOTIDE TRIPHOSPHATE HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17784">
        <property type="entry name" value="Sulfotransfer_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="206"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="217"/>
            <end position="228"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ85357.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="228" mass="26380" checksum="F9779EB5243067D9" modified="2016-11-30" version="1">MAPLEVIGGGFGRTGTESLRTALNMLGYNTHHMLMLFEDPEQDPEDFTNAFHNRDQADWDRIYKNYSAAVDWPSVTFYKDLLKKYPDAKVVLTVRDADSWYKSAKNTIFETAKRTKAEIANNNEKQAISFTKKDPVKLLEMASLVCLDGVFNDEERFSDEEKVKQMFIDHNEEVKRTVPPDQLLVMELGEGWNRLCAFLGKEVPKEPYPRSNSTEQFKQRFTQDMDCK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N8H9</accession>
    <name>A0A1C7N8H9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Type 2A phosphatase-associated protein 42</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">TAP42</name>
        <name evidence="3" type="ORF">A0J61_06582</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000404">
        <property type="protein sequence ID" value="OBZ85367.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="FunCoup" id="A0A1C7N8H9">
        <property type="interactions" value="460"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N8H9"/>
    <dbReference type="InParanoid" id="A0A1C7N8H9"/>
    <dbReference type="OrthoDB" id="10261753at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051721">
        <property type="term" value="F:protein phosphatase 2A binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035303">
        <property type="term" value="P:regulation of dephosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009966">
        <property type="term" value="P:regulation of signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.540">
        <property type="entry name" value="TAP42-like family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038511">
        <property type="entry name" value="TAP42/TAP46-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007304">
        <property type="entry name" value="TAP46-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10933">
        <property type="entry name" value="IMMUNOGLOBULIN-BINDING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10933:SF9">
        <property type="entry name" value="IMMUNOGLOBULIN-BINDING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04177">
        <property type="entry name" value="TAP42"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="232"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="157"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="232"/>
            <end position="243"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ85367.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="355" mass="40739" checksum="41CB830E4C1F6602" modified="2016-11-30" version="1">MSSTLDGLSLGQLFHSGQSILTQLEDSSLSSIDPGYQAQVNDGIQRLTRADDLISKLHIFSDNEIIDDINTNDLKFLLVTAYLGSLTLKLCGKDIERSDILNRSKEFFQRFLSTCQDHELLKKEDIMLMQRLNHNGKAPSLGAAQQREQKIARFKREKAIKEQIQQLRERLDQINAKHGEDEDRDVDETEREMVQALIELEIVRSLENWHSIEQELVMVKEMESMREMMQRAGKDMTVDRREPPTNTRATWGKDKPILTKEGKPLQPFVITNQREQIRSKVFGYGHNLPTMTIDEYLEQEMAQGNIIQGGGEPPEKPLIDDNDYEAQDAEXMKKREWDEFVEANPRGAGNRGNKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N8J2</accession>
    <name>A0A1C7N8J2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Kelch domain-containing protein 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">KLHDC3_0</name>
        <name evidence="4" type="ORF">A0J61_06994</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000450">
        <property type="protein sequence ID" value="OBZ84956.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N8J2"/>
    <dbReference type="STRING" id="101091.A0A1C7N8J2"/>
    <dbReference type="InParanoid" id="A0A1C7N8J2"/>
    <dbReference type="OrthoDB" id="432528at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.80">
        <property type="entry name" value="Kelch-type beta propeller"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000210">
        <property type="entry name" value="BTB/POZ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015915">
        <property type="entry name" value="Kelch-typ_b-propeller"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46093">
        <property type="entry name" value="ACYL-COA-BINDING DOMAIN-CONTAINING PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46093:SF18">
        <property type="entry name" value="FIBRONECTIN TYPE-III DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00651">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24681">
        <property type="entry name" value="Kelch_KLHDC2_KLHL20_DRC7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117281">
        <property type="entry name" value="Kelch motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54695">
        <property type="entry name" value="POZ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50097">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0880">Kelch repeat</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="BTB" evidence="3">
        <location>
            <begin position="389"/>
            <end position="456"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OBZ84956.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="642" mass="73838" checksum="17A45B5B5D9707FD" modified="2016-11-30" version="1">MYTAPIKTTGRNLAGLWRPSFVKVDQRLYVFGGGGNVTDDLHFLDLKTMNWVLIQNASGTPPCKRYGHTATRWKDSIIIFGGCNEYQEYCKDIHIFNLKTSSWHQPTIRGTVCSRYLHSATVFEDKLLIYGGFAKSSDCTYVLDELCVLDLVSMAWTRYHDMPPRYNHSATLVGNKMYIYAGKDEQGNTVSDLFMINLSKLPYTPHLVLSGTQEQQQQSRMVLLKSQHFCDTACGKLLVFGRYLSHQHYYQYTKSQQQQQQQQIQQQQIQQQVQQQQQLQSNYQDSTYSLWMLDLDTLEWEKQECDGHFEVGGWNYFTIIHEKYGTSEESQVNINNLLFLGNTDPYRPQGYDHFRDALVIHGESLGLYDIAEPRSSNEFVQLLNSPELSDFSIIAAKGEEIFVHQVILLTRWPHFKHIHKSGMSEAVEKKMKIPEPVEVIMAFLKFLYSDRLDESEPWQVVCDLMVMANMYLLYRLKKICCERLFKYHLTIESCGLIFEKAILAEETGLKLLTLGFMFQNYGLILKSNLLMDLPPSVQQEFLDYVPKEAVLEVGRTRCLIARNQAQTMYSSMSTSSISTSHSNLIYLRNSSAAQSANTTTAEYYTTSEGFRHSNTQQTMSELIPIQTTNNTTSNSNDMTVEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N8S9</accession>
    <name>A0A1C7N8S9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">2,3-bisphosphoglycerate-independent phosphoglycerate mutase</fullName>
            <ecNumber evidence="6">5.4.2.12</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12">Cofactor-independent phosphoglycerate mutase homolog</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="18" type="primary">ipgm-1</name>
        <name evidence="18" type="ORF">A0J61_06417</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18 19">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>(2R)-2-phosphoglycerate = (2R)-3-phosphoglycerate</text>
            <dbReference type="Rhea" id="RHEA:15901"/>
            <dbReference type="ChEBI" id="CHEBI:58272"/>
            <dbReference type="ChEBI" id="CHEBI:58289"/>
            <dbReference type="EC" id="5.4.2.12"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="4">Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 3/5.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the BPG-independent phosphoglycerate mutase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.4.2.12" evidence="6"/>
    <dbReference type="EMBL" id="LUGH01000386">
        <property type="protein sequence ID" value="OBZ85532.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N8S9"/>
    <dbReference type="STRING" id="101091.A0A1C7N8S9"/>
    <dbReference type="InParanoid" id="A0A1C7N8S9"/>
    <dbReference type="OrthoDB" id="1886626at2759"/>
    <dbReference type="UniPathway" id="UPA00109">
        <property type="reaction ID" value="UER00186"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030145">
        <property type="term" value="F:manganese ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004619">
        <property type="term" value="F:phosphoglycerate mutase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006007">
        <property type="term" value="P:glucose catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006096">
        <property type="term" value="P:glycolytic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd16010">
        <property type="entry name" value="iPGM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.1450.10:FF:000001">
        <property type="entry name" value="2,3-bisphosphoglycerate-independent phosphoglycerate mutase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.720.10:FF:000001">
        <property type="entry name" value="2,3-bisphosphoglycerate-independent phosphoglycerate mutase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.720.10">
        <property type="entry name" value="Alkaline Phosphatase, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1450.10">
        <property type="entry name" value="BPG-independent phosphoglycerate mutase, domain B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01038">
        <property type="entry name" value="GpmI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017850">
        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011258">
        <property type="entry name" value="BPG-indep_PGM_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006124">
        <property type="entry name" value="Metalloenzyme"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036646">
        <property type="entry name" value="PGAM_B_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005995">
        <property type="entry name" value="Pgm_bpd_ind"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01307">
        <property type="entry name" value="pgm_bpd_ind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31637">
        <property type="entry name" value="2,3-BISPHOSPHOGLYCERATE-INDEPENDENT PHOSPHOGLYCERATE MUTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31637:SF0">
        <property type="entry name" value="2,3-BISPHOSPHOGLYCERATE-INDEPENDENT PHOSPHOGLYCERATE MUTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06415">
        <property type="entry name" value="iPGM_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01676">
        <property type="entry name" value="Metalloenzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001492">
        <property type="entry name" value="IPGAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64158">
        <property type="entry name" value="2,3-Bisphosphoglycerate-independent phosphoglycerate mutase, substrate-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53649">
        <property type="entry name" value="Alkaline phosphatase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="10" id="KW-0413">Isomerase</keyword>
    <keyword evidence="9 15" id="KW-0464">Manganese</keyword>
    <keyword evidence="7 15" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Metalloenzyme" evidence="16">
        <location>
            <begin position="17"/>
            <end position="507"/>
        </location>
    </feature>
    <feature type="domain" description="BPG-independent PGAM N-terminal" evidence="17">
        <location>
            <begin position="96"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="active site" description="Phosphoserine intermediate" evidence="13">
        <location>
            <position position="76"/>
        </location>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="24"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="76"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="137"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <begin position="167"/>
            <end position="168"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="199"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="205"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <begin position="270"/>
            <end position="273"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="342"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="409"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="413"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="450"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="451"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="469"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>1</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00002315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004798"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00008819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00012026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00071648"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00083354"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR001492-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PIRSR" id="PIRSR001492-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PIRSR" id="PIRSR001492-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF01676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF06415"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="OBZ85532.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="519" mass="56520" checksum="9D9502A3FF8ACCFD" modified="2016-11-30" version="1">MTGGGEMPKTKQTPKNKACLICIDGWGISPESDSKGDAIRNAETPVMDKLEKEEPFVPIAAHGLSVGLPDGLMGNSEVGHLNIGAGRIVYQDIVRIDLAMKNNEFGKIENIKAAFDRAINGNGRLHFMGLVSDGGVHGHIDHLVSLLTAAKEAGVPESYIHFFGDGRDTAPKSAAKYMSQLVESLKKLGYGKIADINGRYYAMDRDKRWERVQVAFDGMTQAKGEKAEDPVKAIEARYEQDETDEFLKPIIIDEEGQIKDKDTIFTFNFRSDRMREIVQAFGISPTPFDSPVPKDIEIFTMTQYKSDFPFKVAFPAQSMDNVLAEWLSKNDVPQMHIAETEKYAHVTFFFNGGSEAQFEGEERGLVPSPKVATYDLQPEMSAAGVGEKVAEAIESGKYPFVMCNFAPPDMVGHTGVYDAAVKGVAATDKAIGVVLEACKKNGYALFVTADHGNAEKMIADDGESPFTAHTCAKVPFVMADKDAKFAEGVEGALCDVAPTILAYMGLDIPKEMTGKSLLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N8X3</accession>
    <name>A0A1C7N8X3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 9">Ornithine aminotransferase</fullName>
            <ecNumber evidence="4 9">2.6.1.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">car2</name>
        <name evidence="10" type="ORF">A0J61_06364</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>a 2-oxocarboxylate + L-ornithine = L-glutamate 5-semialdehyde + an L-alpha-amino acid</text>
            <dbReference type="Rhea" id="RHEA:13877"/>
            <dbReference type="ChEBI" id="CHEBI:35179"/>
            <dbReference type="ChEBI" id="CHEBI:46911"/>
            <dbReference type="ChEBI" id="CHEBI:58066"/>
            <dbReference type="ChEBI" id="CHEBI:59869"/>
            <dbReference type="EC" id="2.6.1.13"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 9">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2 9">Amino-acid biosynthesis; L-proline biosynthesis; L-glutamate 5-semialdehyde from L-ornithine: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.6.1.13" evidence="4 9"/>
    <dbReference type="EMBL" id="LUGH01000381">
        <property type="protein sequence ID" value="OBZ85592.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N8X3"/>
    <dbReference type="FunCoup" id="A0A1C7N8X3">
        <property type="interactions" value="391"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N8X3"/>
    <dbReference type="InParanoid" id="A0A1C7N8X3"/>
    <dbReference type="OrthoDB" id="10261433at2759"/>
    <dbReference type="UniPathway" id="UPA00098">
        <property type="reaction ID" value="UER00358"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042802">
        <property type="term" value="F:identical protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004587">
        <property type="term" value="F:ornithine aminotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019544">
        <property type="term" value="P:L-arginine catabolic process to L-glutamate"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010121">
        <property type="term" value="P:L-arginine catabolic process to proline via ornithine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055129">
        <property type="term" value="P:L-proline biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006591">
        <property type="term" value="P:ornithine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd00610">
        <property type="entry name" value="OAT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.640.10:FF:000011">
        <property type="entry name" value="Ornithine aminotransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.1150.10:FF:000152">
        <property type="entry name" value="Ornithine aminotransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005814">
        <property type="entry name" value="Aminotrans_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049704">
        <property type="entry name" value="Aminotrans_3_PPA_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050103">
        <property type="entry name" value="Class-III_PLP-dep_AT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010164">
        <property type="entry name" value="Orn_aminotrans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01885">
        <property type="entry name" value="Orn_aminotrans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11986">
        <property type="entry name" value="AMINOTRANSFERASE CLASS III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11986:SF18">
        <property type="entry name" value="ORNITHINE AMINOTRANSFERASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00202">
        <property type="entry name" value="Aminotran_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000521">
        <property type="entry name" value="Transaminase_4ab_Lys_Orn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00600">
        <property type="entry name" value="AA_TRANSFER_CLASS_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 9 10" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="7 8" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 9 10" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004998"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012924"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU365036"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OBZ85592.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="430" mass="47459" checksum="708E763467361C73" modified="2016-11-30" version="1">MTRHSSKEVVQLESNYGAHNYHPLPVVFSEAKGIWVWDPEGNKYMDFLSAYSAVNQGHCHPKIVKALCDQASRLTLSSRAFYNDVYGAYTKYMHDYFGYDMVLPVNTGAEAVETAIKMARKWGYMKKGIPENEAIVLSCENNFHGRTTGVISMSTDPESYGGFGPYLPLVGPKVPQADTLIRYNNLEDLEKVLDVVGKHVAGFLVEPIQGEAGIMVPDDGYLKKAYELCKKHNVLFIADEIQTGLARTGKMLCVDHDQVRPDMVLLGKALSGGVYPVSAVLADRDVMLCIKPGEHGSTYGGNPLGCAVAMAALDVIKEENLVENAERLGQKFREALIQLNSPLVKTVRGRGLLNAIVIDETKSERTAWELCLLLKSRGLLAKPTHVNIIRLAPPLCINEEELMQGVDIIAGALRDIVTMKKEDIPDDLEH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N9F4</accession>
    <name>A0A1C7N9F4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_07965</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000573">
        <property type="protein sequence ID" value="OBZ83984.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N9F4"/>
    <dbReference type="InParanoid" id="A0A1C7N9F4"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="50"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="55"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="66"/>
            <end position="84"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ83984.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="109" mass="11834" checksum="31CA08F40523DB4A" modified="2016-11-30" version="1">MRQSKHIVKKAKLKVVLLLEVLEKIGPVLKKSNGVKAICSDIVDNAQCHDVNASPADNKSGSNAVRSEDMTKSEQNSKDLVKNDLQKSSFVEVEGDHGFANDADSLSEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NAC5</accession>
    <name>A0A1C7NAC5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_06370</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000382">
        <property type="protein sequence ID" value="OBZ85576.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NAC5"/>
    <dbReference type="InParanoid" id="A0A1C7NAC5"/>
    <dbReference type="OrthoDB" id="2279226at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ85576.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="259" mass="30657" checksum="B3695A64D9F59EF5" modified="2016-11-30" version="1">MDQEIATPEPSRRYVQWRDEDVGLLLSDLEQPGHYGKWKENKSGYSKRVAEQVFKSVMYHEAIKFKVRWLESRFHRWHEQLTDPKINQDENAINNIREKMMKEFPYYDRCKPIFSQHDSPMDSPAVQHHVAPAEYTPTSDTNRSITMKPESMHVPTEPVQLETLAYPISIDSHSKRSLEPTDMSVIKKKKHFAKSAFISDVADEKRIKVLEMELELKKMDHHERMQEMKLEQLRLEIELQKLKRDIPLCNQHTNTTTDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NAF0</accession>
    <name>A0A1C7NAF0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Ras-related protein RABB1c</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">RABB1C</name>
        <name evidence="9" type="ORF">A0J61_05873</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Endomembrane system</location>
            <topology evidence="7">Lipid-anchor</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the small GTPase superfamily. Rab family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000330">
        <property type="protein sequence ID" value="OBZ86083.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NAF0"/>
    <dbReference type="STRING" id="101091.A0A1C7NAF0"/>
    <dbReference type="InParanoid" id="A0A1C7NAF0"/>
    <dbReference type="OrthoDB" id="9989112at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000263">
        <property type="entry name" value="Ras-related protein RABB1c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050209">
        <property type="entry name" value="Rab_GTPases_membrane_traffic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001806">
        <property type="entry name" value="Small_GTPase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47979">
        <property type="entry name" value="DRAB11-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00071">
        <property type="entry name" value="Ras"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00449">
        <property type="entry name" value="RASTRNSFRMNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00175">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00176">
        <property type="entry name" value="RAN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00173">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00174">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51419">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51421">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51420">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="5" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-0636">Prenylation</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="178"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="195"/>
            <end position="212"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023289"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00037868"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OBZ86083.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="212" mass="23614" checksum="2A1E7D0F90ABEFEC" modified="2016-11-30" version="1">MSNYNYNYIIKYIIIGDTGVGKSCILLQFTDKRFMPAHDLTIGVGFGTRFITVNDQQIKLQIWDTAGQESFRSITRSYYRGAAGALLVYDITRRETFEHLPVWLEDVRQHANPNTAIMLIGNKCDLEKNRQVSKEEAERFAQEHDLFFLETSAKSSENVEEAFAKTAEAIQKKIQNGTIDMNSETNGVKLAPPQGGSSLPSANSSSNSGGCC</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NAM8</accession>
    <name>A0A1C7NAM8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Clathrin light chain</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">clc1</name>
        <name evidence="8" type="ORF">A0J61_05843</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Clathrin is the major protein of the polyhedral coat of coated pits and vesicles.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Cytoplasmic vesicle membrane</location>
            <topology evidence="1 6">Peripheral membrane protein</topology>
            <orientation evidence="1 6">Cytoplasmic side</orientation>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="6">Membrane</location>
            <location evidence="6">Coated pit</location>
            <topology evidence="6">Peripheral membrane protein</topology>
            <orientation evidence="6">Cytoplasmic side</orientation>
        </subcellularLocation>
        <text evidence="6">Cytoplasmic face of coated pits and vesicles.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the clathrin light chain family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000328">
        <property type="protein sequence ID" value="OBZ86101.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NAM8"/>
    <dbReference type="FunCoup" id="A0A1C7NAM8">
        <property type="interactions" value="287"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NAM8"/>
    <dbReference type="InParanoid" id="A0A1C7NAM8"/>
    <dbReference type="OrthoDB" id="5512at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030132">
        <property type="term" value="C:clathrin coat of coated pit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030130">
        <property type="term" value="C:clathrin coat of trans-Golgi network vesicle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032050">
        <property type="term" value="F:clathrin heavy chain binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005198">
        <property type="term" value="F:structural molecule activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072583">
        <property type="term" value="P:clathrin-dependent endocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000996">
        <property type="entry name" value="Clathrin_L-chain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10639">
        <property type="entry name" value="CLATHRIN LIGHT CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10639:SF7">
        <property type="entry name" value="CLATHRIN LIGHT CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01086">
        <property type="entry name" value="Clathrin_lg_ch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0168">Coated pit</keyword>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5 6" id="KW-0968">Cytoplasmic vesicle</keyword>
    <keyword evidence="3 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="138"/>
            <end position="176"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005263"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU363137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OBZ86101.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="235" mass="26642" checksum="278FC2B888565169" modified="2016-11-30" version="1">MSDFGDFNTPSEDPTADFLARERAALGEDADFFNNDTDLISTSNDLTSPVNLASAASLPTSPAIFESPQIHHQTTDIGFPAQPDNSFTTFETNYPKAEELETSQAFHKALLPEEEPETVRQWREKQAEIIAQRDAEAEAKKEEKIKHAREEIDKFYEDYNDKKQKAIEENREREEVHQKSIEQVASSGNIWERVVKEVDATNAKTGYHSHDVSRMKELMVDLKRDSKAPGNIIEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NAS4</accession>
    <name>A0A1C7NAS4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Putative RWD, RING finger and WD repeat-containing protein C11E3.05</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">A0J61_06126</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000355">
        <property type="protein sequence ID" value="OBZ85819.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="FunCoup" id="A0A1C7NAS4">
        <property type="interactions" value="243"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NAS4"/>
    <dbReference type="InParanoid" id="A0A1C7NAS4"/>
    <dbReference type="OrthoDB" id="311712at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035859">
        <property type="term" value="C:Seh1-associated complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005774">
        <property type="term" value="C:vacuolar membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035591">
        <property type="term" value="F:signaling adaptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034198">
        <property type="term" value="P:cellular response to amino acid starvation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1904263">
        <property type="term" value="P:positive regulation of TORC1 signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049567">
        <property type="entry name" value="WDR59-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049566">
        <property type="entry name" value="WDR59_RTC1-like_RING_Znf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46170">
        <property type="entry name" value="GATOR COMPLEX PROTEIN WDR59"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46170:SF1">
        <property type="entry name" value="GATOR COMPLEX PROTEIN WDR59"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17120">
        <property type="entry name" value="zf-RING_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="130"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="186"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="229"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="domain" description="WDR59/RTC1-like RING zinc finger" evidence="5">
        <location>
            <begin position="1307"/>
            <end position="1356"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="414"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="611"/>
            <end position="652"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="727"/>
            <end position="759"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="617"/>
            <end position="628"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="727"/>
            <end position="744"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF17120"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OBZ85819.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="1363" mass="154064" checksum="406EE3B38156E515" modified="2016-11-30" version="1">MLQIGQQFNRSLSIAMAERQLTRIRRDDNPQEDTFYRALEIKFHHSVGSMSISPASRDVVLAGRQGLVVIDLEDPWLIPRILPHMSKWEVADVQWSPHMARESWVASTSNQKLLVWNLNYTGSRAIEHVFHAHARAISDINWSPHQPDILATCSIDTYVHLWDLREPQVRARNQDDDRKMRPSSSFTPWNAAATQVKFNRKNEYLIASAHDKDVKIWDIRKGAVPVTSIAAHSKKIYGIDWSRQNDHDIVTCSLDKLVKFWNIHTPDQEEEVIVTDTPIWRARNTPFGDGVLIMPQRTDSKLTLYSRACADTPVHAFDGHQDTVKEFVWRWKGDMNGANGDDREFQLVTWSKDQNLRLWPVSEDTMRAVGFEPSKTKTKLSVPSIALEGSKTGSTHSFQQEPIEKSVTDIRSSLTSTPATPTVRLTPNSSNSTGLLPYRSNTINNMSTGYDQNNAYREQKYSAINPLLWMQNVKTVGPTGSEIRRDASKSENSYQSVADEMSTVLNKYLPVGVKTEKINAASRTCTISLHGPWSDAGNALLRITIRFGPQYPDNSPPEFDIQKNSMISIYHRAHMTQDLNALASSYTSHKKWCLEACIRYLLGENMHEESEYGLENQHPSSSVDSSTGVFHGQGSNGSPGHHWRSSNAIDAGDSDDELGQAWGYMGEGYRFGKRESMTSERGIMVDMSVKQSTDAKVPFPRLCGAVFSGNGQLVCFFSTLRVRDNSRKNSDANKNKLQEQEQEQKNQPTQGDHSSGEYFENTYSDFYRHPKTYEQFEEYKEIAAMSRQGRNATVLVGGTGGAFGEYAYDDEQDDIDDGLSSVGTMGGIYYKSDNMALNNTIGSGDNLLYHGAKADRVSHNVIIVDFSDKMPYSPWLAREYILSSKDPVSACIHNAKACQRHGRLDLYKVWCLAVEILRDCVPVKPPESDQMVTDGHHILIDSLDASKVLMDENWQRDQKLAELKSILYNHGATSNTQRKANEQKLLAPFKHVKWGMHPLGQTLINELLQHFIGIGDIQTAAMLSCTFQVRTSKIPSALFGQKPFFADKTPDAIELDYFSLKKVNQRSHSHTLYRANSGPNTDASEKIHITPISHSYGAKTSNRVLSYLSESHEHKRLSPTEQRLMMTDTDSPTFLKRNSRLNRSWTATHPKLKIPSNTAPGIRHHVVGSLGSHSPALSSPLIMTPTTPLINREGKVLHDTSEMKIEFYNMEQFDHERFFENNHIPLMDAKGMAQRDILRICYADMLYRWNLLDQRAEILRFLDCQPFPLEKEIVSSHIQVSCYACGAELSANDKYCFQCHKLRKLIRCSFCHILVKGLVNFCIHCGHGGHSHHMKDWFVTSRQVYCMTGCGCKCALESIEISG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NCD9</accession>
    <name>A0A1C7NCD9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_06937</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000443">
        <property type="protein sequence ID" value="OBZ85014.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NCD9"/>
    <dbReference type="InParanoid" id="A0A1C7NCD9"/>
    <dbReference type="OrthoDB" id="10327191at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008889620" evidence="1">
        <location>
            <begin position="21"/>
            <end position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ85014.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="76" mass="8236" checksum="D98515DAE07215E2" modified="2016-11-30" version="1">MVSVSSLILASLALVATVNALPSDQIHALQKREELARIIESGFTLQPRVCRDPCCVNARSCCIAGGGTWRNNDCQY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NCF7</accession>
    <name>A0A1C7NCF7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Vacuolar morphogenesis protein 7</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">A0J61_05280</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Essential for proper morphogenesis of the vacuole. May exist as structural reinforcement on the surface of the vacuolar membrane and be required for maintenance against rupture by osmotic pressure.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Vacuole</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000281">
        <property type="protein sequence ID" value="OBZ86678.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NCF7"/>
    <dbReference type="FunCoup" id="A0A1C7NCF7">
        <property type="interactions" value="70"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NCF7"/>
    <dbReference type="InParanoid" id="A0A1C7NCF7"/>
    <dbReference type="OrthoDB" id="428895at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000329">
        <property type="term" value="C:fungal-type vacuole membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035091">
        <property type="term" value="F:phosphatidylinositol binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007034">
        <property type="term" value="P:vacuolar transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097576">
        <property type="term" value="P:vacuole fusion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016192">
        <property type="term" value="P:vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd06897">
        <property type="entry name" value="PX_SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd15858">
        <property type="entry name" value="SNARE_VAM7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.5.110:FF:000058">
        <property type="entry name" value="VAM7p Vacuolar SNARE protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1520.10">
        <property type="entry name" value="Phox-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001683">
        <property type="entry name" value="PX_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036871">
        <property type="entry name" value="PX_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000727">
        <property type="entry name" value="T_SNARE_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22775">
        <property type="entry name" value="SORTING NEXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22775:SF3">
        <property type="entry name" value="SORTING NEXIN-13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00787">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00312">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00397">
        <property type="entry name" value="t_SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64268">
        <property type="entry name" value="PX domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF58038">
        <property type="entry name" value="SNARE fusion complex"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50195">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50192">
        <property type="entry name" value="T_SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0926">Vacuole</keyword>
    <feature type="domain" description="PX" evidence="8">
        <location>
            <begin position="3"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="domain" description="T-SNARE coiled-coil homology" evidence="7">
        <location>
            <begin position="340"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="229"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="371"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="234"/>
            <end position="250"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004116"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022554"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00054927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OBZ86678.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="403" mass="46056" checksum="23EEF14459E4884A" modified="2016-11-30" version="1">MSEIIQAIFIRETQIRSVPKPHVVYKVEVHAAVRNWVVWKRYSEFSKLDAQFRSIFPKQPTPTKLPGKRFFPSTFSDPEKIEERRQGLEDYLRGILSSRDDRWRLTDVWKEFLAIPTGRSLDASTSYTSESWLDEYTTMLDTAREIRSLINKKSTHMARHEISASHNCTVQAKKLLMTLSSRLSNLEAGLAGLASITAEGELRRRQDMLATLKDEKDALLKLASTGRQQDQDLLYNSPNNTQNKTNSNHDSTYQINRATTAANKYLDDRKSLFYGDETVNYGFPAQNSETMKEAPKRAHTIGHGRAFGSAALQKQQQQKAAQETEVTRGLDNEGLVVHQQQLMDDQDQQIQQFSAILARQRQLGISIGHELETQNQVLDELDADVDRTQTKLKFANKKLQKIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7ND19</accession>
    <name>A0A1C7ND19_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Splicing factor subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_04950</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the SF3B5 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000254">
        <property type="protein sequence ID" value="OBZ86997.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7ND19"/>
    <dbReference type="FunCoup" id="A0A1C7ND19">
        <property type="interactions" value="333"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7ND19"/>
    <dbReference type="InParanoid" id="A0A1C7ND19"/>
    <dbReference type="OrthoDB" id="274726at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071011">
        <property type="term" value="C:precatalytic spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005686">
        <property type="term" value="C:U2 snRNP"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009846">
        <property type="entry name" value="SF3b5/RDS3-10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017089">
        <property type="entry name" value="Splicing_factor_3B_subunit_5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20978">
        <property type="entry name" value="SPLICING FACTOR 3B SUBUNIT 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20978:SF0">
        <property type="entry name" value="SPLICING FACTOR 3B SUBUNIT 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07189">
        <property type="entry name" value="SF3b10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037010">
        <property type="entry name" value="Splicing_factor_3B_subunit_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009568"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRNR" id="PIRNR037010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ86997.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="84" mass="9542" checksum="F0B10EEF8F5CE018" modified="2016-11-30" version="1">MDRLNINSQIEHLQSKYVGTGHADTIKHEWVANQYRDSLASFVGHNSLLSYISVAENETKARAKMNMLEKMLQPCGPPPEKEDQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NDG1</accession>
    <name>A0A1C7NDG1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Mid2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">A0J61_06538</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000399">
        <property type="protein sequence ID" value="OBZ85414.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NDG1"/>
    <dbReference type="InParanoid" id="A0A1C7NDG1"/>
    <dbReference type="OrthoDB" id="2290099at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071944">
        <property type="term" value="C:cell periphery"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051694">
        <property type="entry name" value="Immunoregulatory_rcpt-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15549:SF26">
        <property type="entry name" value="AXIAL BUDDING PATTERN PROTEIN 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15549">
        <property type="entry name" value="PAIRED IMMUNOGLOBULIN-LIKE TYPE 2 RECEPTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008889635" description="Mid2 domain-containing protein" evidence="7">
        <location>
            <begin position="24"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="161"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="103"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="313"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="103"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="313"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="348"/>
            <end position="357"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OBZ85414.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="357" mass="37523" checksum="00F4B5318437B605" modified="2016-11-30" version="1">MRLSSKTLSTTFVLLFLLTASEAQLSISDDPIVISSAASTTQRASVTSSRALPSATSDATSVIVTRPVPSSSSALPSSSSISTLQPSSSSIVSSVVVPSTTSTISTVAPSRSSTTTLSSTSLPASTSITSESTSSSSSMTSAAPSPTTTQPSDNHQNTTPIIIGSVVGGVVGLALIGGVIACINRRGGCTKRQKKKNDFEDYGLGDFPHQHKTNINSTSAGAGAVSAGAAAGAPMSMNNKTVSPTLPRLNDQGNYYQDDAYGYNNYGNYYDNSMDYGMQPQQQQGGYYYNPQQEYYDNNNAYYYDNSTSATAYSPQQPMHTSHNLHSGVTGXQQYNANAHVPQQNIYKPDDASKAPY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NDK3</accession>
    <name>A0A1C7NDK3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_05304</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000283">
        <property type="protein sequence ID" value="OBZ86636.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NDK3"/>
    <dbReference type="InParanoid" id="A0A1C7NDK3"/>
    <dbReference type="OrthoDB" id="2258660at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="41"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="41"/>
            <end position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ86636.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="124" mass="14019" checksum="FA5557C588190CA9" modified="2016-11-30" version="1">MPRASTIIAGAALVTALTYQSRINLITHTAQIQKEIDHVKDKSDSITRKANEPPTRLSLQRSPSPVERFVDNTSLYYKARLIPSVKEAWNAQVMQFTFALIQSDLPKKCSQFVQRNVFGKQDTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NDL9</accession>
    <name>A0A1C7NDL9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Putative MFS-type transporter C18.02</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">A0J61_04791</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. Vesicular transporter family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000242">
        <property type="protein sequence ID" value="OBZ87158.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NDL9"/>
    <dbReference type="STRING" id="101091.A0A1C7NDL9"/>
    <dbReference type="InParanoid" id="A0A1C7NDL9"/>
    <dbReference type="OrthoDB" id="5086884at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd17325">
        <property type="entry name" value="MFS_MdtG_SLC18_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050930">
        <property type="entry name" value="MFS_Vesicular_Transporter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001958">
        <property type="entry name" value="Tet-R_TetA/multi-R_MdtG-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23506">
        <property type="entry name" value="GH10249P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23506:SF23">
        <property type="entry name" value="GH10249P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01035">
        <property type="entry name" value="TCRTETA"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="73"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="105"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="162"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="186"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="239"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="268"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="304"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="328"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="378"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="403"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="8">
        <location>
            <begin position="19"/>
            <end position="429"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OBZ87158.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="456" mass="49948" checksum="8401B2518DE5B944" modified="2016-11-30" version="1">MNHKELPFLFQLRSSKCFVFSTAATGLFTSTFVHSILFPLSPFIVARIRNIEQNSDPSEDLTSHVDSNSRDTGILVALYAVGLLVGSPIFGWLGDRIAQRRLPMLLGTAASIAANILFMLSTTYPMLLAARLLQGISNACVWTMCLCLVADNWPREQLGVQMGKLIGFYPLGMMIGLPAGGHKAPFIASMLLSGIDFLMRLIVIERSSSPASWFADEPPRETEKTNSVTWLQLLRQPRLIVSLLLTSTVATVMSAFEPTLSMRMAQEWQFNAAGCSLIVLAYMIPSILASVVCGWLCDRLGTKIVALCSLLFATPSCLLIGFPDHERGSFWILVPFLVMGGITIAGCQAPVFPEIAKVVDTSNGHTQSSDGLARSYSLFNAAYGVGMCVGPILGGYLYAWIGFFWLCTLLSGLFLCFIPLAYFFIGDSRALIERNRLNAIDTVKDMEKSSLYTHDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NDN9</accession>
    <name>A0A1C7NDN9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Endonuclease/exonuclease/phosphatase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_05054</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000263">
        <property type="protein sequence ID" value="OBZ86889.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NDN9"/>
    <dbReference type="InParanoid" id="A0A1C7NDN9"/>
    <dbReference type="OrthoDB" id="2282565at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.10.10">
        <property type="entry name" value="Endonuclease/exonuclease/phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036691">
        <property type="entry name" value="Endo/exonu/phosph_ase_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56219">
        <property type="entry name" value="DNase I-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ86889.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="273" mass="31227" checksum="867E1A338FECEE7F" modified="2016-11-30" version="1">MAFLRSTTYPTFIMGDFNFDIRQPAPIEPTWLALLNDNFDNCFLNDYLPTFTSTHGNHRLLDYIFCSIPYSSQVRSSAQDFVNYAWTDHNLLSISFRASASNRGSGTWKANPMLAKLPSFRSGLIEHLLQVIDDHRYLAPDCTLSDQEIWDSLKVDVKAFVKSFQLGRNSWRTKALKRLQSKCNHIFRQYRHTVIWSTLLPSVEYLISTLQTEIAEVTALQAGTFWKEKGERSPGLLKRLACTLADQRDIPFLLNPSSSRLIDSTDDKTAVMS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NE06</accession>
    <name>A0A1C7NE06_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_04627</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000230">
        <property type="protein sequence ID" value="OBZ87322.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NE06"/>
    <dbReference type="InParanoid" id="A0A1C7NE06"/>
    <dbReference type="OrthoDB" id="2153609at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12937">
        <property type="entry name" value="F-box-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00256">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="1">
        <location>
            <begin position="5"/>
            <end position="44"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00256"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ87322.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="202" mass="22852" checksum="F3C758FD78E66D60" modified="2016-11-30" version="1">MDCLLPSEIISTIMSYMSIKDLARMERTSRLFQAFALQEIEHRIIKSSSNSDEWGVLIHLGQASAKPIRFDSRTKKAYYSILMDPVKIKTMFDHRRSVHCSLLRKNKTTKYQSFNEKGFIITVEKGMQEGKTVELDIKNDACQVHAALTRLPSSVNTNDPVSCGKQQTKLENVQPIKSMAPTPLLYTLQITELSLPLSTIAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NEG4</accession>
    <name>A0A1C7NEG4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_04448</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000218">
        <property type="protein sequence ID" value="OBZ87492.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NEG4"/>
    <dbReference type="InParanoid" id="A0A1C7NEG4"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="88"/>
            <end position="111"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ87492.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="130" mass="14752" checksum="C6837586C71E8CC9" modified="2016-11-30" version="1">MNAWKQAANERKEHARARITVRARASTPAPVQKSRKYAVPLTITAVAFTCTLSSYLVESAPPVIQDTTAQSNSCSSFCVCYSSCFICLVFWCIFCCYFAYAYLICIGYRLYVVARHAYWKINQKKAYEIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NEP8</accession>
    <name>A0A1C7NEP8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">NAD-dependent histone deacetylase HST3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">HST3_1</name>
        <name evidence="7" type="ORF">A0J61_04360</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the sirtuin family. Class I subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000212">
        <property type="protein sequence ID" value="OBZ87582.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NEP8"/>
    <dbReference type="FunCoup" id="A0A1C7NEP8">
        <property type="interactions" value="62"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NEP8"/>
    <dbReference type="InParanoid" id="A0A1C7NEP8"/>
    <dbReference type="OrthoDB" id="2919105at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017136">
        <property type="term" value="F:histone deacetylase activity, NAD-dependent"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070403">
        <property type="term" value="F:NAD+ binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1600.10">
        <property type="entry name" value="SIR2/SIRT2 'Small Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1220">
        <property type="entry name" value="TPP-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029035">
        <property type="entry name" value="DHS-like_NAD/FAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050134">
        <property type="entry name" value="NAD-dep_sirtuin_deacylases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003000">
        <property type="entry name" value="Sirtuin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026591">
        <property type="entry name" value="Sirtuin_cat_small_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026590">
        <property type="entry name" value="Ssirtuin_cat_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11085:SF8">
        <property type="entry name" value="NAD-DEPENDENT HISTONE DEACETYLASE HST3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11085">
        <property type="entry name" value="NAD-DEPENDENT PROTEIN DEACYLASE SIRTUIN-5, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02146">
        <property type="entry name" value="SIR2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52467">
        <property type="entry name" value="DHS-like NAD/FAD-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50305">
        <property type="entry name" value="SIRTUIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0520">NAD</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Deacetylase sirtuin-type" evidence="6">
        <location>
            <begin position="11"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="311"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="338"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="358"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="370"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="4">
        <location>
            <position position="142"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="150"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="153"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="175"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="178"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006924"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50305"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OBZ87582.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="380" mass="43172" checksum="823ABCAFE676FCE3" modified="2016-11-30" version="1">MKKTIVISEPSEVIDPLLTELSSFIAKSKRAIVVTGAGISCSSGIPDFRSSDGLYNLVKKRHPDIVLRGKELFDATLFRNEKTIKCFYTFMAELRSMITHAEPTITHEFIQSLTEKGQLLRCYTQNIDFLEDNLNIPAIQLHGTMKEVRCTLCSTTFDFTDEYEQQFRDGEAPGCPQCESADAERVRLGKRQLSTGTLRPAIVLYNEDHPQGDSIGQSQINDLKKKPDLMIVMGTSLKIPALKKFIKQAARIIHTKPGGCVVFVNRTSPTKEWEKVFDYEVMGDSDRWVELTNEKLADEKLMNQTASKIRRQLAQKEQEEEDEEDEKENKKGRKTSAKKTITIRSSNSKRPPLKRTLSKSQTTLQEFTTKRRQTVKTKAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NF05</accession>
    <name>A0A1C7NF05_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Androgen-induced gene 1 protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">A0J61_04277</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000205">
        <property type="protein sequence ID" value="OBZ87677.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NF05"/>
    <dbReference type="FunCoup" id="A0A1C7NF05">
        <property type="interactions" value="178"/>
    </dbReference>
    <dbReference type="InParanoid" id="A0A1C7NF05"/>
    <dbReference type="OrthoDB" id="1898221at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006838">
        <property type="entry name" value="ADTRP_AIG1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10989">
        <property type="entry name" value="ANDROGEN-INDUCED PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10989:SF16">
        <property type="entry name" value="AT02829P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04750">
        <property type="entry name" value="Far-17a_AIG1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="44"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="73"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="112"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="144"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="172"/>
            <end position="196"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OBZ87677.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="216" mass="24652" checksum="AB974F753C95AF47" modified="2016-11-30" version="1">MSSLLSLVLNTVGLVSNIYALKNINSEEFENPYALGFGGQYQYLTILGLTTATVAFALKIVRNFYPKFSDTIHEVVTNIATPLEGVISVLYWSMMLLDPHLIIPKDIPSPPLLLDFTLHLFPAIFLWIDFLVFNAEFKRSSRHVGVIYGFAAFYYVWSWYCQTVNGYWPYPFLGDFTLVMRTAFFVGAGVLAWGMYEFGALVHRKIHALEQHQKTQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NFA5</accession>
    <name>A0A1C7NFA5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Protein RTA1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">RTA1</name>
        <name evidence="6" type="ORF">A0J61_04307</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000208">
        <property type="protein sequence ID" value="OBZ87640.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NFA5"/>
    <dbReference type="FunCoup" id="A0A1C7NFA5">
        <property type="interactions" value="36"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NFA5"/>
    <dbReference type="InParanoid" id="A0A1C7NFA5"/>
    <dbReference type="OrthoDB" id="3358017at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007568">
        <property type="entry name" value="RTA1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31465">
        <property type="entry name" value="PROTEIN RTA1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31465:SF1">
        <property type="entry name" value="PROTEIN RTA1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04479">
        <property type="entry name" value="RTA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="20"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="53"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="80"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="125"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="163"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="204"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="239"/>
            <end position="261"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OBZ87640.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="304" mass="34576" checksum="D7BFF24B7997047D" modified="2016-11-30" version="1">MADASGTVPYKLQPIDLFHYIPNLPLAIICAILFLFFFFYLTYRVKRSKSPRFLYILPITSLFEFLGYVIRLKVRTDITIATYAVMTLFLLLPPNALALVNYKCAGEIIRLSNAEPKHFFLRPRFVTWFFFASDIFAFVMQGAGGGLQGTGDPDLSNMGSKIAMIGLAVQLLFFGSFAVITVYLDRKPEYVYTIQGQDQPKKKLIHCLYITTALLYIRAIYRIIEFAGGYDGPVASAEWAFYVFDSLVLFLCFVFYSVLYIGNYLPKRDEDDQSSKGWRGALSTEDVALTNIEKGNTNNYPHRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NFF8</accession>
    <name>A0A1C7NFF8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">C3HC-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">A0J61_04122</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000194">
        <property type="protein sequence ID" value="OBZ87842.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NFF8"/>
    <dbReference type="STRING" id="101091.A0A1C7NFF8"/>
    <dbReference type="InParanoid" id="A0A1C7NFF8"/>
    <dbReference type="OrthoDB" id="2592092at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013909">
        <property type="entry name" value="NuBaID_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012935">
        <property type="entry name" value="NuBaID_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15835">
        <property type="entry name" value="NUCLEAR-INTERACTING PARTNER OF ALK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15835:SF6">
        <property type="entry name" value="ZINC FINGER C3HC-TYPE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08600">
        <property type="entry name" value="NuBaID_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07967">
        <property type="entry name" value="zf-C3HC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C3HC-type" evidence="6">
        <location>
            <begin position="53"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="domain" description="NuBaID C-terminal" evidence="7">
        <location>
            <begin position="212"/>
            <end position="267"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF07967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF08600"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OBZ87842.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="333" mass="38823" checksum="325A607A05F2EB96" modified="2016-11-30" version="1">MDDDLRKEAQELRDLVARIRKETRLLPTLKRPRETDKEEIEAEKPVKVQKTVWDSAGLMTRLKTFNTLYHCAPRPISALDGAKHGWRHKATQEDATAVLGCEDCSQTMYVIEIPIRYQHKPEAIQAISYYKKGLLQCHQEDCPWRYHGCKSTTYTFPLTTLLEGLDRLRNEARSFMTVASSIPTLKHPLSTEAFHKLKFVVSHFEKTEEIDAYLLSLFGWTLLHPDLPGIQCDLCFSQKGFFQLDKLDVLEEHKPYCPWRTGEEEQSGYEWMMGIVSMEYNLLIKRQDLSLASDFERTERFYRLKQTMLQSEKTLLAWQARIEAVAKSKEPLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NG10</accession>
    <name>A0A1C7NG10_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">RlpA-like protein double-psi beta-barrel domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_04005</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000186">
        <property type="protein sequence ID" value="OBZ87958.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NG10"/>
    <dbReference type="STRING" id="101091.A0A1C7NG10"/>
    <dbReference type="InParanoid" id="A0A1C7NG10"/>
    <dbReference type="OrthoDB" id="623670at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd22191">
        <property type="entry name" value="DPBB_RlpA_EXP_N-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.40.10">
        <property type="entry name" value="RlpA-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051477">
        <property type="entry name" value="Expansin_CellWall"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036908">
        <property type="entry name" value="RlpA-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31836">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31836:SF28">
        <property type="entry name" value="SRCR DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50685">
        <property type="entry name" value="Barwin-like endoglucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="157"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="174"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="237"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="253"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="265"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="280"/>
            <end position="304"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ87958.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="304" mass="34463" checksum="451E412B0F5EC9CF" modified="2016-11-30" version="1">MITQMTLMMSLIHARPFEDKDITKRLLGGVQQSTYRGGGTYFYPKTQGGPIGACGPYEDNNSQIVALNADQYGPLDQRSDWCGKKVKICHRKICTVATITDACPRCEYGGLDLTPAVWDQLYGDRSRGVLDIVWSLFDEAEQNSILQSVEKKVLEKISPMKPVQQKSVKEKPTHPKSVKQSHAHKKSSQHKSAKRKSSQHKSAKKNSVKQKFVRQKLVQKKVIQQKPTPTKLIENKPTPTKSVEKTSTQQPNAIQQPKATQQPKPAKEEESKEEQAKKEEEEEKQEDDEDTDDDEDEDEEDENE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NG80</accession>
    <name>A0A1C7NG80_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">L-galactose dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">LGALDH</name>
        <name evidence="2" type="ORF">A0J61_04380</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000213">
        <property type="protein sequence ID" value="OBZ87566.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NG80"/>
    <dbReference type="STRING" id="101091.A0A1C7NG80"/>
    <dbReference type="InParanoid" id="A0A1C7NG80"/>
    <dbReference type="OrthoDB" id="5286008at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045290">
        <property type="term" value="F:D-arabinose 1-dehydrogenase [NAD(P)+] activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070485">
        <property type="term" value="P:dehydro-D-arabinono-1,4-lactone biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="entry name" value="NADP-dependent oxidoreductase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020471">
        <property type="entry name" value="AKR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036812">
        <property type="entry name" value="NAD(P)_OxRdtase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023210">
        <property type="entry name" value="NADP_OxRdtase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42686">
        <property type="entry name" value="GH17980P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42686:SF1">
        <property type="entry name" value="GH17980P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00248">
        <property type="entry name" value="Aldo_ket_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51430">
        <property type="entry name" value="NAD(P)-linked oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NADP-dependent oxidoreductase" evidence="1">
        <location>
            <begin position="15"/>
            <end position="292"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ87566.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="332" mass="37425" checksum="FFC61B8D076FD220" modified="2016-11-30" version="1">MSKPVPQDRFATSEVSFGAGALSGNYDAFSQTDTVEACREALSTGINSFDTSPYYGKSEYFLGDALLEIRNEFPRDHYYLATKVGRYGYTVKEFDYSAKRTYESVAESMKRLHTDYLDVVYCHDVEFVSFEEVVGPNQALEALFDLKSQGKIKYVGCSGYPLDVLLKVAEHQHAKGQPLDIVLSYCHYTLQNTLFADYAPKFKAAGVRYLMNASPLCMALLRDEKTPEWHPAYPAIREAADKAAAIAKENGLSISDLASRFAYQGKDQYGFDATLIGLARKSEVQDAMRAWKDSKRKNTETEDRVFEQIHALFAPHKNYSWQSPTDKELCKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NGL7</accession>
    <name>A0A1C7NGL7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Phosphatidylinositol-specific phospholipase C X domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_03658</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000161">
        <property type="protein sequence ID" value="OBZ88291.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NGL7"/>
    <dbReference type="InParanoid" id="A0A1C7NGL7"/>
    <dbReference type="OrthoDB" id="2343482at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008081">
        <property type="term" value="F:phosphoric diester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.190">
        <property type="entry name" value="Phosphatidylinositol (PI) phosphodiesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017946">
        <property type="entry name" value="PLC-like_Pdiesterase_TIM-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000909">
        <property type="entry name" value="PLipase_C_PInositol-sp_X_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00388">
        <property type="entry name" value="PI-PLC-X"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51695">
        <property type="entry name" value="PLC-like phosphodiesterases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008889691" description="Phosphatidylinositol-specific phospholipase C X domain-containing protein" evidence="1">
        <location>
            <begin position="20"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="domain" description="Phosphatidylinositol-specific phospholipase C X" evidence="2">
        <location>
            <begin position="77"/>
            <end position="164"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00388"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ88291.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="367" mass="41281" checksum="7160DD7028AE313D" modified="2016-11-30" version="1">MKALLVSLIALGLSSVTTAQYSDEVSVEAVGDYDDFDVGFSEALEGAPPCNGFPEYRKIPVNQAFYVGAHQAGSDAFENGSQTRNILQTLEDGIRLLDINLCKDQEGQLVVCSDNAPSKNTFSNVLEQAFTFARNEVEQFFVLHIKSKDSSADVKEIETVIDQICEIHTNKTQGADEFAAGKCSFIYTYNPEKAPWKSMGEIVNYDPEMAQWEGDGELVGVRTKFMLTLADNVKSSDNYTPSYVTPVFWRSVTNEAGSHEELKQTLHQTCRVPEQGIVLGPLDQQTSTPDYLEDALLNKDACNFNDAPLNTYFTAIFVDHYEHQLPYLKELERRMMDVNYAKWTGNYKTMTPSLFISKKKRFDHDEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NGP8</accession>
    <name>A0A1C7NGP8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 13">Tryptophan synthase</fullName>
            <ecNumber evidence="5 13">4.2.1.20</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="primary">trp-3</name>
        <name evidence="15" type="ORF">A0J61_03684</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12 13">
            <text>(1S,2R)-1-C-(indol-3-yl)glycerol 3-phosphate + L-serine = D-glyceraldehyde 3-phosphate + L-tryptophan + H2O</text>
            <dbReference type="Rhea" id="RHEA:10532"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:33384"/>
            <dbReference type="ChEBI" id="CHEBI:57912"/>
            <dbReference type="ChEBI" id="CHEBI:58866"/>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
            <dbReference type="EC" id="4.2.1.20"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 13">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2 13">Amino-acid biosynthesis; L-tryptophan biosynthesis; L-tryptophan from chorismate: step 5/5.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">In the C-terminal section; belongs to the TrpB family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">In the N-terminal section; belongs to the TrpA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.20" evidence="5 13"/>
    <dbReference type="EMBL" id="LUGH01000163">
        <property type="protein sequence ID" value="OBZ88267.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NGP8"/>
    <dbReference type="FunCoup" id="A0A1C7NGP8">
        <property type="interactions" value="423"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NGP8"/>
    <dbReference type="InParanoid" id="A0A1C7NGP8"/>
    <dbReference type="OrthoDB" id="10050244at2759"/>
    <dbReference type="UniPathway" id="UPA00035">
        <property type="reaction ID" value="UER00044"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004834">
        <property type="term" value="F:tryptophan synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd06446">
        <property type="entry name" value="Trp-synth_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd04724">
        <property type="entry name" value="Tryptophan_synthase_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.70:FF:000151">
        <property type="entry name" value="Tryptophan synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1100:FF:000001">
        <property type="entry name" value="Tryptophan synthase beta chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1100:FF:000004">
        <property type="entry name" value="Tryptophan synthase beta chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1100">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00131">
        <property type="entry name" value="Trp_synth_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00133">
        <property type="entry name" value="Trp_synth_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011060">
        <property type="entry name" value="RibuloseP-bd_barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006653">
        <property type="entry name" value="Trp_synth_b_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006654">
        <property type="entry name" value="Trp_synth_beta"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023026">
        <property type="entry name" value="Trp_synth_beta/beta-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018204">
        <property type="entry name" value="Trp_synthase_alpha_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002028">
        <property type="entry name" value="Trp_synthase_suA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001926">
        <property type="entry name" value="TrpB-like_PALP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036052">
        <property type="entry name" value="TrpB-like_PALP_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00262">
        <property type="entry name" value="trpA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00263">
        <property type="entry name" value="trpB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48077:SF3">
        <property type="entry name" value="TRYPTOPHAN SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48077">
        <property type="entry name" value="TRYPTOPHAN SYNTHASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00291">
        <property type="entry name" value="PALP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00290">
        <property type="entry name" value="Trp_syntA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51366">
        <property type="entry name" value="Ribulose-phoshate binding barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53686">
        <property type="entry name" value="Tryptophan synthase beta subunit-like PLP-dependent enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00167">
        <property type="entry name" value="TRP_SYNTHASE_ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00168">
        <property type="entry name" value="TRP_SYNTHASE_BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 13" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="10 13" id="KW-0057">Aromatic amino acid biosynthesis</keyword>
    <keyword evidence="11 13" id="KW-0456">Lyase</keyword>
    <keyword evidence="9 13" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 13" id="KW-0822">Tryptophan biosynthesis</keyword>
    <feature type="domain" description="Tryptophan synthase beta chain-like PALP" evidence="14">
        <location>
            <begin position="352"/>
            <end position="675"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004733"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005761"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00006095"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00018724"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022822"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00049047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU003663"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF00291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="OBZ88267.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="701" mass="76200" checksum="47989645CB71CEE8" modified="2016-11-30" version="1">MATGLRNAFKNAQEQNRPAFVTFLTAGYPSPDITVDNLIALEKGGADVIELGIPFTDPLADGPTIQYASTAALKHGVDIPMCLQMVRDARSRGLKVPVVFMGYYNPILAYGEEKMVKDCKDAGVNGYILVDLPPEESHEFRSICYKYGLSYIPLIAPSTTEARIQLLSKIADSFIYVVSRMGVTGAKDSVSSELPTIIQRIKKYTQAPLAVGFGVSTREHFVEVGSHSEGVVIGSRIITLIKDALEENKNVPQIVQQYASEITGRKEVEIPAAADAELADLEVNDAAGRGPFTGNDIKKFYQLEPRFGEFGGAYVPEALVDCLTQLEACFSDAMKDPAFKEEFESYYDYISRPSQLQLASRLTEDAGGAKIWLKREDLNHTGSHKINNAVGQILLAKRLGKKRIIAETGAGQHGVATATVCAKFGMECVVYMGEEDCRRQALNVFRMRMLGATVVPVTNGARTLKDAINEAMRDWVANVTTTHYLVGSAIGPHPFPMIVREFQSVIGKETKRQMLEKAGKLPDAVVACVGGGSNSIGMFHPFIEDKTVRIVGVEAGGDGVDTEKHSATLTKGTPGVLHGTRTYLLQDLKGQIIETHSVSAGLDYPGVGPEHAYLKDSGRAQYCVADDTQCLIGFRKLTQLEGIIPALESSHAIFAAHQLASQLPKDQDIVVCLSGRGDKDMHTVAEVLPKLGPKINWDLTF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NGP9</accession>
    <name>A0A1C7NGP9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="10 14">6-phosphogluconate dehydrogenase, decarboxylating</fullName>
            <ecNumber evidence="10 14">1.1.1.44</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="primary">6-PGD</name>
        <name evidence="16" type="ORF">A0J61_03686</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 10">Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9 10 14">
            <text>6-phospho-D-gluconate + NADP(+) = D-ribulose 5-phosphate + CO2 + NADPH</text>
            <dbReference type="Rhea" id="RHEA:10116"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58121"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:58759"/>
            <dbReference type="EC" id="1.1.1.44"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 10 14">Carbohydrate degradation; pentose phosphate pathway; D-ribulose 5-phosphate from D-glucose 6-phosphate (oxidative stage): step 3/3.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4 10">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 10 14">Belongs to the 6-phosphogluconate dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.44" evidence="10 14"/>
    <dbReference type="EMBL" id="LUGH01000163">
        <property type="protein sequence ID" value="OBZ88273.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NGP9"/>
    <dbReference type="FunCoup" id="A0A1C7NGP9">
        <property type="interactions" value="563"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NGP9"/>
    <dbReference type="InParanoid" id="A0A1C7NGP9"/>
    <dbReference type="OrthoDB" id="434986at2759"/>
    <dbReference type="UniPathway" id="UPA00115">
        <property type="reaction ID" value="UER00410"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004616">
        <property type="term" value="F:phosphogluconate dehydrogenase (decarboxylating) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019521">
        <property type="term" value="P:D-gluconate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009051">
        <property type="term" value="P:pentose-phosphate shunt, oxidative branch"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1040.10:FF:000002">
        <property type="entry name" value="6-phosphogluconate dehydrogenase, decarboxylating"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.5.320:FF:000002">
        <property type="entry name" value="6-phosphogluconate dehydrogenase, decarboxylating"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000007">
        <property type="entry name" value="6-phosphogluconate dehydrogenase, decarboxylating"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.320">
        <property type="entry name" value="6-Phosphogluconate Dehydrogenase, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1040.10">
        <property type="entry name" value="N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008927">
        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013328">
        <property type="entry name" value="6PGD_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006114">
        <property type="entry name" value="6PGDH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006113">
        <property type="entry name" value="6PGDH_Gnd/GntZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006115">
        <property type="entry name" value="6PGDH_NADP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006184">
        <property type="entry name" value="6PGdom_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006183">
        <property type="entry name" value="Pgluconate_DH"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00873">
        <property type="entry name" value="gnd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006765">
        <property type="entry name" value="PRK09287.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11811">
        <property type="entry name" value="6-PHOSPHOGLUCONATE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00393">
        <property type="entry name" value="6PGD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03446">
        <property type="entry name" value="NAD_binding_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000109">
        <property type="entry name" value="6PGD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00076">
        <property type="entry name" value="6PGDHDRGNASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM01350">
        <property type="entry name" value="6PGD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48179">
        <property type="entry name" value="6-phosphogluconate dehydrogenase C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00461">
        <property type="entry name" value="6PGD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 14" id="KW-0311">Gluconate utilization</keyword>
    <keyword evidence="5 10 14" id="KW-0521">NADP</keyword>
    <keyword evidence="6 10 14" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8 10 14" id="KW-0570">Pentose shunt</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="6-phosphogluconate dehydrogenase C-terminal" evidence="15">
        <location>
            <begin position="182"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="11">
        <location>
            <position position="186"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="11">
        <location>
            <position position="193"/>
        </location>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <begin position="12"/>
            <end position="17"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <begin position="35"/>
            <end position="37"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <begin position="77"/>
            <end position="79"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="105"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" description="in other chain" evidence="12">
        <location>
            <position position="105"/>
        </location>
        <ligand>
            <name>substrate</name>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" description="in other chain" evidence="12">
        <location>
            <begin position="131"/>
            <end position="133"/>
        </location>
        <ligand>
            <name>substrate</name>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" description="in other chain" evidence="12">
        <location>
            <begin position="189"/>
            <end position="190"/>
        </location>
        <ligand>
            <name>substrate</name>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" description="in other chain" evidence="12">
        <location>
            <position position="194"/>
        </location>
        <ligand>
            <name>substrate</name>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" description="in other chain" evidence="12">
        <location>
            <position position="263"/>
        </location>
        <ligand>
            <name>substrate</name>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" description="in other chain" evidence="12">
        <location>
            <position position="290"/>
        </location>
        <ligand>
            <name>substrate</name>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="448"/>
        </location>
        <ligand>
            <name>substrate</name>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="454"/>
        </location>
        <ligand>
            <name>substrate</name>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002526"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004874"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008419"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023064"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00048640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRNR" id="PIRNR000109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR000109-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR000109-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR000109-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU000485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="SMART" id="SM01350"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="OBZ88273.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="484" mass="52837" checksum="FD14D1BD2CE3158F" modified="2016-11-30" version="1">MVEAVADIGLIGLAVMGQNLILNMNDHGYTVCAYNRTTSKVDDFLNNEAKGTKVVGAHSVEELCAKLKRPRKVMLLVKAGSAVDAFIDQLLPYLEEGDIIIDGGNSHFPDSIRRAEELEKKGILFVGSGVSGGEEGARFGPSLMPGGNPKAWPAIKDIFQDISAKAPDGAPCCDWVGETGAGHYVKMVHNGIEYGDMQLICEVYQIMKEGLGLSHDEMANTFEEWNKGELDSFLIEITRDILKYKDTDGAPLVEKILDTAGQKGTGKWTGIDSLDRGIPVTLIGEAVYARCLSSLKGERTRASKILKGPTAKFEGDKTKFIAQLGQALYASKIVSYAQGFMLMRQAAKDNNWNLNNAGIALMWRGGCIIRSVFLGKIKDAYTNNPELENLLFDPFFQKATEDAQESWRAVIATAVQMGIPTPALSTALNFYDGLRHEILPANLLQAQRDYFGAHTYELLESPGKWVHTNWTGKGGNVSASTYLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NGR9</accession>
    <name>A0A1C7NGR9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 13">Hypoxanthine phosphoribosyltransferase</fullName>
            <ecNumber evidence="5 13">2.4.2.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="primary">Hprt1</name>
        <name evidence="15" type="ORF">A0J61_03608</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>IMP + diphosphate = hypoxanthine + 5-phospho-alpha-D-ribose 1-diphosphate</text>
            <dbReference type="Rhea" id="RHEA:17973"/>
            <dbReference type="ChEBI" id="CHEBI:17368"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58017"/>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
            <dbReference type="EC" id="2.4.2.8"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 13">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3 13">Purine metabolism; IMP biosynthesis via salvage pathway; IMP from hypoxanthine: step 1/1.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 13">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 13">Belongs to the purine/pyrimidine phosphoribosyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.2.8" evidence="5 13"/>
    <dbReference type="EMBL" id="LUGH01000158">
        <property type="protein sequence ID" value="OBZ88351.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NGR9"/>
    <dbReference type="STRING" id="101091.A0A1C7NGR9"/>
    <dbReference type="InParanoid" id="A0A1C7NGR9"/>
    <dbReference type="OrthoDB" id="9449045at2759"/>
    <dbReference type="UniPathway" id="UPA00591">
        <property type="reaction ID" value="UER00648"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004422">
        <property type="term" value="F:hypoxanthine phosphoribosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032263">
        <property type="term" value="P:GMP salvage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006178">
        <property type="term" value="P:guanine salvage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046100">
        <property type="term" value="P:hypoxanthine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032264">
        <property type="term" value="P:IMP salvage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006166">
        <property type="term" value="P:purine ribonucleoside salvage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06223">
        <property type="entry name" value="PRTases_typeI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.2020:FF:000053">
        <property type="entry name" value="Hypoxanthine phosphoribosyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2020">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050408">
        <property type="entry name" value="HGPRT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005904">
        <property type="entry name" value="Hxn_phspho_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029057">
        <property type="entry name" value="PRTase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000836">
        <property type="entry name" value="PRTase_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01203">
        <property type="entry name" value="HGPRTase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43340:SF1">
        <property type="entry name" value="HYPOXANTHINE PHOSPHORIBOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43340">
        <property type="entry name" value="HYPOXANTHINE-GUANINE PHOSPHORIBOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00156">
        <property type="entry name" value="Pribosyltran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53271">
        <property type="entry name" value="PRTase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 13" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7 13 15" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="12 13" id="KW-0460">Magnesium</keyword>
    <keyword evidence="9 13" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11 13" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10 13" id="KW-0660">Purine salvage</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 13 15" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Phosphoribosyltransferase" evidence="14">
        <location>
            <begin position="41"/>
            <end position="194"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004669"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00008391"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011895"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022726"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU364099"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF00156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="OBZ88351.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="217" mass="24519" checksum="28BD525BC938B017" modified="2016-11-30" version="1">MDPKDWIDVTVEKNHYSLDHFVIPNHYEEDVTSILIPHGVIMDRIRKLARMIVDDSQGPLVVCCILKGGHQYFADLVNEIKKLRRLNGTSVPLSLEFVRVKSYENDQSTGGVKISLTDSELEEFKGKNLLIVEDIIDTGATMVRLLDRLGAIQPNSIKVTSLLLKKTERSNGYVPDYVGFAIPDAFVVGYALDYNEYFRDLDHICVISDVGKKKYAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NI56</accession>
    <name>A0A1C7NI56_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">A0J61_03210</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000134">
        <property type="protein sequence ID" value="OBZ88735.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NI56"/>
    <dbReference type="STRING" id="101091.A0A1C7NI56"/>
    <dbReference type="InParanoid" id="A0A1C7NI56"/>
    <dbReference type="OrthoDB" id="415315at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45667">
        <property type="entry name" value="S-ADENOSYLMETHIONINE MITOCHONDRIAL CARRIER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 8 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 9" id="KW-0813">Transport</keyword>
    <feature type="repeat" description="Solcar" evidence="8">
        <location>
            <begin position="6"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="8">
        <location>
            <begin position="94"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="8">
        <location>
            <begin position="222"/>
            <end position="317"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU000488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OBZ88735.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="320" mass="35619" checksum="4DC337466AF84EBD" modified="2016-11-30" version="1">MTSVVDQFKINFTSGAVGLSLSYACMHPLDTVKTRIQADTTGHWRKVIFSRATLHSLGKGFFVSALGAAGQGGARFSTYEYCKSRMLPKEKNALTIPVTALSAVLGDLASSVIKVPREVITAKLQIDHYQTATNKRPTAAFVIRQTLLEEGPKGLFRGFWAIAARDSPFMIILLVSYENFKAFHHRSVREAIKKTREYRLKQKNVVAGAAFEELEANIPTMRSVVYGGVSGFLAGYFTTPMDVLRTRMIAQKSAQSVTVMTMARSMIARSWSRQDISPVRKSINTYHAFFAGAIPRSLWWFGICGIFFPSYETLKSLMSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NI87</accession>
    <name>A0A1C7NI87_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">sn-1-specific diacylglycerol lipase</fullName>
            <ecNumber evidence="14">3.1.1.116</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">A0J61_04905</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>a 1,2-diacyl-sn-glycerol + H2O = a 2-acylglycerol + a fatty acid + H(+)</text>
            <dbReference type="Rhea" id="RHEA:33275"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17389"/>
            <dbReference type="ChEBI" id="CHEBI:17815"/>
            <dbReference type="ChEBI" id="CHEBI:28868"/>
            <dbReference type="EC" id="3.1.1.116"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="13">
            <dbReference type="Rhea" id="RHEA:33276"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.116" evidence="14"/>
    <dbReference type="EMBL" id="LUGH01000251">
        <property type="protein sequence ID" value="OBZ87044.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NI87"/>
    <dbReference type="InParanoid" id="A0A1C7NI87"/>
    <dbReference type="OrthoDB" id="438440at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016298">
        <property type="term" value="F:lipase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016042">
        <property type="term" value="P:lipid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00519">
        <property type="entry name" value="Lipase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035892">
        <property type="entry name" value="C2_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052214">
        <property type="entry name" value="DAG_Lipase-Related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002921">
        <property type="entry name" value="Fungal_lipase-type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45792">
        <property type="entry name" value="DIACYLGLYCEROL LIPASE HOMOLOG-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45792:SF8">
        <property type="entry name" value="DIACYLGLYCEROL LIPASE-ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01764">
        <property type="entry name" value="Lipase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49562">
        <property type="entry name" value="C2 domain (Calcium/lipid-binding domain, CaLB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-0106">Calcium</keyword>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-0442">Lipid degradation</keyword>
    <keyword evidence="11" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="12" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="Fungal lipase-type" evidence="16">
        <location>
            <begin position="592"/>
            <end position="731"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="187"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="291"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="339"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="808"/>
            <end position="858"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="915"/>
            <end position="966"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="15">
        <location>
            <begin position="193"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="15">
        <location>
            <begin position="923"/>
            <end position="941"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="15">
        <location>
            <begin position="953"/>
            <end position="966"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022963"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00024531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00026104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF01764"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="OBZ87044.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="966" mass="109305" checksum="22D81627ADCB52DC" modified="2016-11-30" version="1">MENALESLPSSNVSPLNRRLSLPDLKKLREEWDRREAVQASAQVLPGKLQIDLLNVRSDVVVKRPLMRLRMGSQHYFSSRSKHTNGNWNEGFLFTISYHNQLFDTIELDLYDKRNKWRSKAKHIGKAKLKIAKLKDREDVFVTFLPMYEYHVKRYLPAHIQLPHTFLKSHMPNMARFTQYTNNLKRPNLLRPSKTDISEDANDHHDSIRTNDVTDHEQDKLYADIPPTYELHPSHSKNSMTPYIGSIQVRVRYSFQHPPIDNESDTLSPFYFAHSNRSMDTFSSLMTASRKSSRRSSTYSSSSSAHSSSAASTSYIKKDYHDAIEPRLIIVEDLQTIQEASSPLTPKPKHTEDGQKKMLPRSESTVEFMFHQSLDQNFRRNNIDLDQHNVDFPKNDGENKKKNLATELVSDTASIKSHNFGDKNFAFRWINESFEEVAISHPSLDRMIGMVVSPQTRILLRAVVKVFHAFGQGFKITILQLISSLSLLQNFYAEVPRPPPAEKINDLKFLDEAYYFLGHAIIAYGWRGISYLGDYAKYLKDVVKTKSNKEAIVRYLKIPQEDLLGYEYGLRKGAVFQPSYFVSYDRAHEAVVLGIRGTWSLYDCITDLVCEYRPWKGGLVHSGILASAQWFFTRIIPQIFLYVSEQTESSGRPVSSFIITGHSLGAGTAAVLTMMVADHIDQLRELSKNPNFKVHCYSYAPVASVSLDLSEKYKDHIDSFVCQDDLVGRLSYGTASCAKELIMDSVIAVDGLGGANKVNNNPSTRQECFSIIQARRNEIYHNKEPRYPLLYVPGCVYQFRRGKASAADKVPTAQDIQLPGTKSTPHRPRATSSADKRRRSIPTSLSHSEPVLSKSSTNTKTATADDVCFTLHKSSPMLSEEVLISKTCLEDHMVVTYLTAFQMARQGAMRQDAFRSYQKDNSHTPTASTSTSSSLSSSTSTAVENSAKPKIQLPSTSSFSQGLNVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NIU2</accession>
    <name>A0A1C7NIU2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">rRNA adenine N(6)-methyltransferase</fullName>
            <ecNumber evidence="10">2.1.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">dim1</name>
        <name evidence="12" type="ORF">A0J61_03003</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 18S rRNA in the 40S particle.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>adenosine(1779)/adenosine(1780) in 18S rRNA + 4 S-adenosyl-L-methionine = N(6)-dimethyladenosine(1779)/N(6)-dimethyladenosine(1780) in 18S rRNA + 4 S-adenosyl-L-homocysteine + 4 H(+)</text>
            <dbReference type="Rhea" id="RHEA:42780"/>
            <dbReference type="Rhea" id="RHEA-COMP:10234"/>
            <dbReference type="Rhea" id="RHEA-COMP:10236"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:74411"/>
            <dbReference type="ChEBI" id="CHEBI:74493"/>
            <dbReference type="EC" id="2.1.1.183"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="8 9 10">Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.-" evidence="10"/>
    <dbReference type="EMBL" id="LUGH01000122">
        <property type="protein sequence ID" value="OBZ88945.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NIU2"/>
    <dbReference type="FunCoup" id="A0A1C7NIU2">
        <property type="interactions" value="473"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NIU2"/>
    <dbReference type="InParanoid" id="A0A1C7NIU2"/>
    <dbReference type="OrthoDB" id="74991at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030688">
        <property type="term" value="C:preribosome, small subunit precursor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052909">
        <property type="term" value="F:18S rRNA (adenine(1779)-N(6)/adenine(1780)-N(6))-dimethyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000462">
        <property type="term" value="P:maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.480:FF:000002">
        <property type="entry name" value="rRNA adenine N(6)-methyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.150:FF:000007">
        <property type="entry name" value="rRNA adenine N(6)-methyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.480">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001737">
        <property type="entry name" value="KsgA/Erm"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020596">
        <property type="entry name" value="rRNA_Ade_Mease_Trfase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020598">
        <property type="entry name" value="rRNA_Ade_methylase_Trfase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011530">
        <property type="entry name" value="rRNA_adenine_dimethylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00755">
        <property type="entry name" value="ksgA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11727">
        <property type="entry name" value="DIMETHYLADENOSINE TRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11727:SF7">
        <property type="entry name" value="DIMETHYLADENOSINE TRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00398">
        <property type="entry name" value="RrnaAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00650">
        <property type="entry name" value="rADc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01131">
        <property type="entry name" value="RRNA_A_DIMETH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51689">
        <property type="entry name" value="SAM_RNA_A_N6_MT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 9 10" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 9" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="2 10" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="5 9 10" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="4 9 10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Ribosomal RNA adenine methylase transferase N-terminal" evidence="11">
        <location>
            <begin position="40"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="33"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="35"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="60"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="81"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="109"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="124"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00049478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00061109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU362106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM00650"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="OBZ88945.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="309" mass="34977" checksum="588157775AEE60E9" modified="2016-11-30" version="1">MPKLTAKAAQKANNAQEDMRAFGPIFNKDLGQHILKNPLVAQGIVDKANLVGSDTVLEIGPGTGNLTVRILQACKKVVAVEMDPRLAAELQKRVHGTPDQKKLHILLGDFMKTELPYFDVCISNTPYQISSVLVFKLLEHRPMFRVAILMFQREFALRLVAKPGDELYCRLSVNVQLLAKVDHVMKVGKNNFRPPPKVESSVVRLEPKNPPPPVDFKEFDGLLRILFTRKHKTFSANFKQTTVLNMLEQNYKTYCAAHEMMVESEFDIKQKVVQILDSVNMSEMRAARCDLDDFLKLLLAFNTANIHFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NIU6</accession>
    <name>A0A1C7NIU6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">N-acetyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_04706</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000236">
        <property type="protein sequence ID" value="OBZ87244.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NIU6"/>
    <dbReference type="STRING" id="101091.A0A1C7NIU6"/>
    <dbReference type="InParanoid" id="A0A1C7NIU6"/>
    <dbReference type="OrthoDB" id="5689at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016747">
        <property type="term" value="F:acyltransferase activity, transferring groups other than amino-acyl groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04301">
        <property type="entry name" value="NAT_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050276">
        <property type="entry name" value="MshD_Acetyltransferase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43617">
        <property type="entry name" value="L-AMINO ACID N-ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="7"/>
            <end position="178"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ87244.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="178" mass="20259" checksum="3C34D21A9A6C2A2B" modified="2016-11-30" version="1">MVQPATIFVRKALPSDIKYVQEATKIVNAAYRSEGGWTTEKDIVGGLRCTEEDMKHFVEESGQPNTLLLAFDEETVVGTLQIQPMKSEEKEAEIGLFSVSPLYQSRGIGGKLIRQALIEMQQLGFTFAVMHVLENRPEILSWYRKLGFSETGERIPFIWPEMLKVDKDLHFLTLKKPI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NIX0</accession>
    <name>A0A1C7NIX0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Putative E3 ubiquitin-protein ligase HERC2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">HERC2</name>
        <name evidence="6" type="ORF">A0J61_03199</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000133">
        <property type="protein sequence ID" value="OBZ88759.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NIX0"/>
    <dbReference type="STRING" id="101091.A0A1C7NIX0"/>
    <dbReference type="InParanoid" id="A0A1C7NIX0"/>
    <dbReference type="OrthoDB" id="61110at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.30">
        <property type="entry name" value="Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058923">
        <property type="entry name" value="RCC1-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009091">
        <property type="entry name" value="RCC1/BLIP-II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000408">
        <property type="entry name" value="Reg_chr_condens"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051210">
        <property type="entry name" value="Ub_ligase/GEF_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22870:SF408">
        <property type="entry name" value="OS09G0560450 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22870">
        <property type="entry name" value="REGULATOR OF CHROMOSOME CONDENSATION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00415">
        <property type="entry name" value="RCC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13540">
        <property type="entry name" value="RCC1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25390">
        <property type="entry name" value="WD40_RLD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00633">
        <property type="entry name" value="RCCNDNSATION"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50985">
        <property type="entry name" value="RCC1/BLIP-II"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00626">
        <property type="entry name" value="RCC1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50012">
        <property type="entry name" value="RCC1_3"/>
        <property type="match status" value="6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008889722" evidence="4">
        <location>
            <begin position="29"/>
            <end position="503"/>
        </location>
    </feature>
    <feature type="repeat" description="RCC1" evidence="2">
        <location>
            <begin position="41"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="domain" description="RCC1-like" evidence="5">
        <location>
            <begin position="62"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="repeat" description="RCC1" evidence="2">
        <location>
            <begin position="95"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="repeat" description="RCC1" evidence="2">
        <location>
            <begin position="147"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="repeat" description="RCC1" evidence="2">
        <location>
            <begin position="202"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="repeat" description="RCC1" evidence="2">
        <location>
            <begin position="380"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="repeat" description="RCC1" evidence="2">
        <location>
            <begin position="449"/>
            <end position="501"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="328"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="337"/>
            <end position="346"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF25390"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OBZ88759.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="503" mass="55046" checksum="D089CEB7B27FB8A6" modified="2016-11-30" version="1">MAPSSSIADLSTHYLFFFFLCTMDLVSSLPSSSDPRKQEAGTLYMVGSKNISKEEHEKINKQDITHPIRVEGLENVPIVKVSASPLHVLALSQEGNIYSWGDPQYGALGRKGNPHFPAPINHPSIRYIRFKEVVCGVTFSMALSSKGQLYTWGTYMGSENIYGYLPHVKIQYHPRIVDNVSGVQFVSIAAGATDCLALDSNGQVYSWGCGEFNQLGIPGCHNKKTKLELIPNKIALNRIVRIACGQFHSLAINSYGQLFAWGVNKFYQCGIMSNALPKEEVEEEILGPESIIAPQLVPGFKNCVGTETDHLKSKLGKRSLDEIQQGFSKRLRISTENQDDMMDTDDSSEKRNSEAKQPIKPGPVSVAAGADHTIVQMSDNSLVAFGRNDHGQLGIVIDPKNPLPGAVQTRKDGNYDALGIPLRNPWSPSVKIKKGISGFDHTLIIGTNGQVWGYGSAEHHQLGTYKSKDVTLPTLIESIQQSGKVIDGAANDATTYFIVANKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NIX2</accession>
    <name>A0A1C7NIX2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Putative phospholipase</fullName>
            <ecNumber evidence="4">3.1.1.47</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">paf-2</name>
        <name evidence="6" type="ORF">A0J61_02911</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>a 1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine + H2O = a 1-O-alkyl-sn-glycero-3-phosphocholine + acetate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17777"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30089"/>
            <dbReference type="ChEBI" id="CHEBI:30909"/>
            <dbReference type="ChEBI" id="CHEBI:36707"/>
            <dbReference type="EC" id="3.1.1.47"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the serine esterase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.47" evidence="4"/>
    <dbReference type="EMBL" id="LUGH01000117">
        <property type="protein sequence ID" value="OBZ89043.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NIX2"/>
    <dbReference type="FunCoup" id="A0A1C7NIX2">
        <property type="interactions" value="12"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NIX2"/>
    <dbReference type="InParanoid" id="A0A1C7NIX2"/>
    <dbReference type="OrthoDB" id="2363873at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003847">
        <property type="term" value="F:1-alkyl-2-acetylglycerophosphocholine esterase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016042">
        <property type="term" value="P:lipid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016715">
        <property type="entry name" value="PAF_acetylhydro_eukaryote"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10272">
        <property type="entry name" value="PLATELET-ACTIVATING FACTOR ACETYLHYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10272:SF0">
        <property type="entry name" value="PLATELET-ACTIVATING FACTOR ACETYLHYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03403">
        <property type="entry name" value="PAF-AH_p_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF018169">
        <property type="entry name" value="PAF_acetylhydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 4 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 4" id="KW-0442">Lipid degradation</keyword>
    <keyword evidence="3 4" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" description="Nucleophile" evidence="5">
        <location>
            <position position="212"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="5">
        <location>
            <position position="236"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="5">
        <location>
            <position position="296"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022963"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRNR" id="PIRNR018169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR018169-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OBZ89043.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="371" mass="42484" checksum="5AB2F9214D30D5E6" modified="2016-11-30" version="1">MTLFFGNFPSLSGQFDVGCRDIEWEDRQFSKKNSSDCKSVFMRLYYPARLKKGDTKANWVPHPDYAKALCDLAKLPTFVSNWLSKAASSKKTRFYQEADMLETEQPFPVIVFSHGLGGNRLVYSCICSDLASHGFVVAAIEHREGSASLAKGIEDQWIRYVNIPPEIWSFRHHQLRHRVAEVNLTLDCLDHLAQKEFKGRLDMSQMVMAGHSFGGATTILMLNDEESRFQCGLLLDPWAQPLMMMDKHIQIKRPVIAILSEQFFFWPDNYESVQELIDHAGCASQNVCLTLNGTEHQHQSDVMIVLRYLTLFDFRSPFQIHPSKAIELNTEASVQFIKNILSAPKPLKRKKRKSTLRMMAKKPKISHLNLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NIY6</accession>
    <name>A0A1C7NIY6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_04663</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000233">
        <property type="protein sequence ID" value="OBZ87284.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NIY6"/>
    <dbReference type="STRING" id="101091.A0A1C7NIY6"/>
    <dbReference type="InParanoid" id="A0A1C7NIY6"/>
    <dbReference type="OrthoDB" id="5860629at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ87284.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="149" mass="16956" checksum="C568AFBB9B88DFD3" modified="2016-11-30" version="1">MLLYHVSDAPSSGDLRTVRGVCYPTFQAAARALGLLASDNQWKECLEEAAHMQSPVSLRIIFVSFDPADPYQLWLDFKSKLSKDHWYQLHENPAFDPTVDDIHETACNYALIDIKDILQSHYGTSLQWYDQLQLPSVDCRIDPIGLSLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-06-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NJ12</accession>
    <name>A0A1C7NJ12_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_03158</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000131">
        <property type="protein sequence ID" value="OBZ88789.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NJ12"/>
    <dbReference type="InParanoid" id="A0A1C7NJ12"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ88789.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="112" mass="13141" checksum="7FA90B157A398455" modified="2016-11-30" version="1">MKRANWRVACLTKNNEQTVVVAVFDNEEDLLKWFKDVGFWPALRKINDEEEGESPTEAYLYSTSENDAHEKGFFKKNPEKGDDKAAYDRSEDSFLVIGERTTLDTIYLYRYK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NJ22</accession>
    <name>A0A1C7NJ22_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Trehalase</fullName>
            <ecNumber evidence="4">3.2.1.28</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">Alpha-trehalose glucohydrolase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">treh</name>
        <name evidence="6" type="ORF">A0J61_03161</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>alpha,alpha-trehalose + H2O = alpha-D-glucose + beta-D-glucose</text>
            <dbReference type="Rhea" id="RHEA:32675"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15903"/>
            <dbReference type="ChEBI" id="CHEBI:16551"/>
            <dbReference type="ChEBI" id="CHEBI:17925"/>
            <dbReference type="EC" id="3.2.1.28"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the glycosyl hydrolase 37 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.28" evidence="4"/>
    <dbReference type="EMBL" id="LUGH01000131">
        <property type="protein sequence ID" value="OBZ88799.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NJ22"/>
    <dbReference type="STRING" id="101091.A0A1C7NJ22"/>
    <dbReference type="InParanoid" id="A0A1C7NJ22"/>
    <dbReference type="OrthoDB" id="3542292at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004555">
        <property type="term" value="F:alpha,alpha-trehalase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005993">
        <property type="term" value="P:trehalose catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008928">
        <property type="entry name" value="6-hairpin_glycosidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012341">
        <property type="entry name" value="6hp_glycosidase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001661">
        <property type="entry name" value="Glyco_hydro_37"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018232">
        <property type="entry name" value="Glyco_hydro_37_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23403">
        <property type="entry name" value="TREHALASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23403:SF1">
        <property type="entry name" value="TREHALASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01204">
        <property type="entry name" value="Trehalase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00744">
        <property type="entry name" value="GLHYDRLASE37"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48208">
        <property type="entry name" value="Six-hairpin glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00927">
        <property type="entry name" value="TREHALASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00928">
        <property type="entry name" value="TREHALASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="2 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008889724" description="Trehalase" evidence="5">
        <location>
            <begin position="23"/>
            <end position="617"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005615"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU361180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OBZ88799.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="617" mass="70497" checksum="72376AC2FAE0AE89" modified="2016-11-30" version="1">MPSLRFICGALLAQIALVSVSAIQNNGDNYSCDSPIYCEGPLLKTIQLARIFPDSKTFVDMPTSKSESEVLTAFDQIGGVNATRDQLQQFLNDNFLTAGAELKRLQNISITNPSWLDKIENPDYHGWANQLNEAWANLTFTYDYSDLCEDCVTSTLPVNRPFVVPGGRFREFYYWDTYFVIRGLLLSSQNELAKNMLENFFDLIEKHGFIPNGPRIYYLNRSQPPFLSHMIQEYYDKTGDEDFMSKALPYLDKEYQGWIANTTVQIADPNNRNVKYKLNRYITENTSPRPESYLEDYNTVNNGTDFTDEVKKQMYADIAAGAESGWDYSSRWTRQKAPAPDQKENYEMLRSINTANVIPIDLNSLLWHTESKLAKWYTQFGKQNKSTKKKAVYYSKQAKDRLKAMYNIMWNETDTSFYDFNLTSHSQSIQYTPANVYPIWNGALPDKILKNETITRKLFDETENALKKYKGVLTTSYYYTTMQWDYPNGWPPLSFIAMDAMLRLEQLTKKNITTSSGTSLDRLSRVLGERYAASAYCGWVNTGGSIPGVLEKVNKTVEDNGHMFEKFDVNTIGVSGSQGEYVSQTGFGWTNGIALWVLDTWSNITAPDCTQPVTLNI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-06-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NJB8</accession>
    <name>A0A1C7NJB8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_04550</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000226">
        <property type="protein sequence ID" value="OBZ87394.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NJB8"/>
    <dbReference type="InParanoid" id="A0A1C7NJB8"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ87394.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="51" mass="5919" checksum="52BCA8A378BEAA5B" modified="2016-11-30" version="1" fragment="single">MSYEEKKIAETNLKKISEEIEDLPAVLKQGQGRFNLKQTNHKAKEMKGEEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NJS1</accession>
    <name>A0A1C7NJS1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Cyclic nucleotide-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">A0J61_04415</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000216">
        <property type="protein sequence ID" value="OBZ87534.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NJS1"/>
    <dbReference type="InParanoid" id="A0A1C7NJS1"/>
    <dbReference type="OrthoDB" id="421051at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00038">
        <property type="entry name" value="CAP_ED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="entry name" value="Jelly Rolls"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000595">
        <property type="entry name" value="cNMP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018490">
        <property type="entry name" value="cNMP-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51206">
        <property type="entry name" value="cAMP-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50042">
        <property type="entry name" value="CNMP_BINDING_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="32"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="67"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="248"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="domain" description="Cyclic nucleotide-binding" evidence="3">
        <location>
            <begin position="148"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="199"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="320"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="361"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="205"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="225"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="324"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="366"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="404"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OBZ87534.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="404" mass="46092" checksum="B6926D34327E5C91" modified="2016-11-30" version="1" fragment="single">MDXTIKSVTVPPPSEVLYETVQQPHRSLLTRILGFLPMTLLRLVSFATISVPLFFYRILTWSFTLHLNFSSLLVVLAVIATVVYLIVRYRFLTKYSRLKPITQPPKVASSFDLHPDTEEDDYADFSKTGGYKNYPDEFLSAFLSSIKIFGYLEQPVFHELARHLQTKKLLAGDTLFRNPEQERSFYIVVDGHVQMFVKPENSDSSQDDDNDTTSDSDFEDYHQPWRTQSDQFDSGTTRKRDKFKNYTLINEVGAGGTLSSLFTILSIFRESFNRSEAKERHRQRSTQHAHRNTSSRIAPMLMDHLANTGSEEWRQVFPGLEDSSGLNSRPDSDNSNPHRMNKAATMATAISQLTSELDDGYFAGEQDGHESEHLETTNEIAMPAPLRTTSIPPSYKNRDSPRRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NKI0</accession>
    <name>A0A1C7NKI0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_02312</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000085">
        <property type="protein sequence ID" value="OBZ89637.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NKI0"/>
    <dbReference type="InParanoid" id="A0A1C7NKI0"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="26"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="26"/>
            <end position="39"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ89637.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="72" mass="8323" checksum="FD5D22837C5CA34A" modified="2016-11-30" version="1">MVVLNLSCFSINLCGLVQHNLQSHAYKEKPKKETSHDFEGDPDEKDNIPCFEFKTKQKTSPILKQKKGRRFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NL73</accession>
    <name>A0A1C7NL73_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Cell pattern formation-associated protein stuA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">stuA_1</name>
        <name evidence="7" type="ORF">A0J61_03899</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the EFG1/PHD1/stuA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000179">
        <property type="protein sequence ID" value="OBZ88044.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NL73"/>
    <dbReference type="STRING" id="101091.A0A1C7NL73"/>
    <dbReference type="InParanoid" id="A0A1C7NL73"/>
    <dbReference type="OrthoDB" id="5407653at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.260.10">
        <property type="entry name" value="Transcription regulator HTH, APSES-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029790">
        <property type="entry name" value="EFG1/Phd1/StuA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036887">
        <property type="entry name" value="HTH_APSES_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018004">
        <property type="entry name" value="KilA/APSES_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003163">
        <property type="entry name" value="Tscrpt_reg_HTH_APSES-type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47792">
        <property type="entry name" value="PROTEIN SOK2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47792:SF1">
        <property type="entry name" value="PROTEIN SOK2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04383">
        <property type="entry name" value="KilA-N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01252">
        <property type="entry name" value="KilA-N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54616">
        <property type="entry name" value="DNA-binding domain of Mlu1-box binding protein MBP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51299">
        <property type="entry name" value="HTH_APSES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH APSES-type" evidence="6">
        <location>
            <begin position="129"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="272"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="272"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="286"/>
            <end position="302"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007247"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51299"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OBZ88044.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="302" mass="35274" checksum="69A2227D723F34BE" modified="2016-11-30" version="1">MQSNPYQYENRNNNSYSPHSTRNEYEYYPHQERLIDSETLYSYFEGQNNTSYHSQQQWRRPTINLDLIDNDSNSHCTKSNVMKPLPPLHPAPTATTFMSHSDIHSCQPSTAYQKTSKYYSKCIGSSRPRLTATLWEDENVMYYQIDCRGICVARRQDNDMINGTKLLNVAGISRGKRDGILKNERGRVVVKVGAIHLKGVWIPLSRAKVLATQFHIFEDLYPLLSDHPVSYLYPSCIQQLYRMNSNVYRDRHIKHERLPAYTYDMHYLSKEKEHSTHINEREHIRQTSSSQIAQGSDMTLYP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NLZ5</accession>
    <name>A0A1C7NLZ5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Rho-type GTPase-activating protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">rga1_3</name>
        <name evidence="10" type="ORF">A0J61_01920</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000067">
        <property type="protein sequence ID" value="OBZ90020.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NLZ5"/>
    <dbReference type="FunCoup" id="A0A1C7NLZ5">
        <property type="interactions" value="225"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NLZ5"/>
    <dbReference type="InParanoid" id="A0A1C7NLZ5"/>
    <dbReference type="OrthoDB" id="20689at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030036">
        <property type="term" value="P:actin cytoskeleton organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd09392">
        <property type="entry name" value="LIM2_Lrg1p_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.110.10">
        <property type="entry name" value="Cysteine Rich Protein"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.555.10">
        <property type="entry name" value="Rho GTPase activation protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008936">
        <property type="entry name" value="Rho_GTPase_activation_prot"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000198">
        <property type="entry name" value="RhoGAP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001781">
        <property type="entry name" value="Znf_LIM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24215">
        <property type="entry name" value="RHO-GTPASE-ACTIVATING PROTEIN LRG1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24215:SF10">
        <property type="entry name" value="RHO-GTPASE-ACTIVATING PROTEIN LRG1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00412">
        <property type="entry name" value="LIM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00620">
        <property type="entry name" value="RhoGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00132">
        <property type="entry name" value="LIM"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00324">
        <property type="entry name" value="RhoGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57716">
        <property type="entry name" value="Glucocorticoid receptor-like (DNA-binding domain)"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48350">
        <property type="entry name" value="GTPase activation domain, GAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00478">
        <property type="entry name" value="LIM_DOMAIN_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50023">
        <property type="entry name" value="LIM_DOMAIN_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50238">
        <property type="entry name" value="RHOGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0440">LIM domain</keyword>
    <keyword evidence="2 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 6" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="LIM zinc-binding" evidence="8">
        <location>
            <begin position="20"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="domain" description="LIM zinc-binding" evidence="8">
        <location>
            <begin position="82"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="domain" description="LIM zinc-binding" evidence="8">
        <location>
            <begin position="384"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="domain" description="Rho-GAP" evidence="9">
        <location>
            <begin position="734"/>
            <end position="936"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="571"/>
            <end position="625"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1060"/>
            <end position="1111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="579"/>
            <end position="592"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="594"/>
            <end position="616"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="1060"/>
            <end position="1071"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="1078"/>
            <end position="1091"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="1100"/>
            <end position="1111"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="10">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50238"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OBZ90020.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="1111" mass="126058" checksum="4B3C21C1D85A01AF" modified="2016-11-30" version="1" fragment="single">KMSQLSPTITSSPTSIKPTLVCSKCDMPLGEQLVRALDNAFHPECFTCRDCNVPVASRYLPHPTEPGQPLCERDYFKRLDLVCAQCDEPLRGTYIIALDKKYHTNHFNCSDCSTVFGPEDSYYEHNSKVYCHFHYSTRFAVSCTGCDMSILKQYVEIERNDTVDHWHPECYMIQKFWNVKIAYPTLKENESIVSRVPKPQTPLELLKTQKETEEKVIGIWSVLSAFEESSAVCISEMLLHVSNGAYIESICLSERFLVHVEALFAGIDQIQSVYLEYKQTEFKYTREAKMLCKKIINFFSLLSRTGDIELKKLGSTQELLSLVTGLAHYLKILIRLALTSALRLEITIGKPICVSRLLAKLMEIPGKERHSRDSQRLIKPKNTDYCQLCGVTIEDQCMRYGDYRWHMGCFKCRQCSRQLNANDDAVFNSASCTVHCLECSGLTRNDLTPFEYITKLNQYSFLLRIALSRLCNLLQITDNQLSSVDYSTKLKSPNTILKDANANVQLSPSAEKQLTLMTDERIQGIDVFPTEIVDAKIAVSSTSKLDRKMSRSFKSANKRSTILGNADLAASLRSQKDSPTTPINRNITPPTRMDSLQRTANQQNELPTPSKLQQNTTRHKPTRSVGLDDLPQMVAEAVSSRKPATNSTQQNIHITTGPSGQPRIYLSELSALQYMIIRYVAVVQIEEYVKSSFSSGELLNLIETKKSSIWGKFFPFKKQKSHMPKVKEEGTFGVPLDLLTERTGVESNLGSGHSPVKLAAFIDDSITAMRQMDMTVEGVFRKNGNIRRLKELTEALDRNPNEVDLSQENVVQVAALLKKFLRDLPDPLMTHRLHPLFMAIERIEDATERKRALHLACCMLPRCNRATMEVLFVFFRWVASFSHVTGNVGSRMDIPNLARVIAPNILTANHKDPLKDDSFASIRVVEVLLESYEEFCLVPDDLEPFLEDPNLSEVDMSPKEFLKRVEQTVRLKNNPNGTSTCSKLSLQSTAQENARLFDNTIADGRAHPPTSIYAQQQFLPYANHHPNSDFVPQQLNMRYHQNNPVPPPRRMDSHESFASHNLQPYDTSQSAPKHRYVSHYQQQSQQHYYQQPLNPPHPTPTTSNAISTPSH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NM10</accession>
    <name>A0A1C7NM10_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="14">NADH-ubiquinone oxidoreductase subunit, mitochondrial</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">nuo78</name>
        <name evidence="14" type="ORF">A0J61_01838</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="9">
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the complex I 75 kDa subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000063">
        <property type="protein sequence ID" value="OBZ90105.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NM10"/>
    <dbReference type="SMR" id="A0A1C7NM10"/>
    <dbReference type="STRING" id="101091.A0A1C7NM10"/>
    <dbReference type="InParanoid" id="A0A1C7NM10"/>
    <dbReference type="OrthoDB" id="10249365at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008137">
        <property type="term" value="F:NADH dehydrogenase (ubiquinone) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016651">
        <property type="term" value="F:oxidoreductase activity, acting on NAD(P)H"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042773">
        <property type="term" value="P:ATP synthesis coupled electron transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00207">
        <property type="entry name" value="fer2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd02773">
        <property type="entry name" value="MopB_Res-Cmplx1_Nad11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.740:FF:000012">
        <property type="entry name" value="NADH dehydrogenase [ubiquinone] iron-sulfur protein 1 mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.20.740:FF:000001">
        <property type="entry name" value="NADH-quinone oxidoreductase subunit G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.20:FF:000002">
        <property type="entry name" value="NADH-ubiquinone oxidoreductase 75 kDa subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.740">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.740">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.228.10">
        <property type="entry name" value="Dimethylsulfoxide Reductase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036010">
        <property type="entry name" value="2Fe-2S_ferredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001041">
        <property type="entry name" value="2Fe-2S_ferredoxin-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006656">
        <property type="entry name" value="Mopterin_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006963">
        <property type="entry name" value="Mopterin_OxRdtase_4Fe-4S_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000283">
        <property type="entry name" value="NADH_UbQ_OxRdtase_75kDa_su_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054351">
        <property type="entry name" value="NADH_UbQ_OxRdtase_ferredoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010228">
        <property type="entry name" value="NADH_UbQ_OxRdtase_Gsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019574">
        <property type="entry name" value="NADH_UbQ_OxRdtase_Gsu_4Fe4S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015405">
        <property type="entry name" value="NDUFS1-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050123">
        <property type="entry name" value="Prok_molybdopt-oxidoreductase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01973">
        <property type="entry name" value="NuoG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43105:SF13">
        <property type="entry name" value="NADH-UBIQUINONE OXIDOREDUCTASE 75 KDA SUBUNIT, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43105">
        <property type="entry name" value="RESPIRATORY NITRATE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13510">
        <property type="entry name" value="Fer2_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22151">
        <property type="entry name" value="Fer4_NDSU1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22117">
        <property type="entry name" value="Fer4_Nqo3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00384">
        <property type="entry name" value="Molybdopterin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10588">
        <property type="entry name" value="NADH-G_4Fe-4S_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09326">
        <property type="entry name" value="NADH_dhqG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00929">
        <property type="entry name" value="NADH-G_4Fe-4S_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54292">
        <property type="entry name" value="2Fe-2S ferredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54862">
        <property type="entry name" value="4Fe-4S ferredoxins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53706">
        <property type="entry name" value="Formate dehydrogenase/DMSO reductase, domains 1-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51085">
        <property type="entry name" value="2FE2S_FER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51839">
        <property type="entry name" value="4FE4S_HC3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51669">
        <property type="entry name" value="4FE4S_MOW_BIS_MGD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00641">
        <property type="entry name" value="COMPLEX1_75K_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00642">
        <property type="entry name" value="COMPLEX1_75K_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00643">
        <property type="entry name" value="COMPLEX1_75K_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="6" id="KW-0408">Iron</keyword>
    <keyword evidence="7" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0520">NAD</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-1278">Translocase</keyword>
    <keyword evidence="14" id="KW-0830">Ubiquinone</keyword>
    <feature type="domain" description="2Fe-2S ferredoxin-type" evidence="11">
        <location>
            <begin position="33"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="domain" description="4Fe-4S His(Cys)3-ligated-type" evidence="13">
        <location>
            <begin position="111"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="domain" description="4Fe-4S Mo/W bis-MGD-type" evidence="12">
        <location>
            <begin position="250"/>
            <end position="306"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00034078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU004523"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51669"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="OBZ90105.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="730" mass="80025" checksum="AB040E747A5006DB" modified="2016-11-30" version="1">MLRVLNKTSVARRTPALLKTGVRAFAASTNVKEEVEVFIDGKSVMIEQGAALIQACEKAGADIPRFCYHERLSVAGNCRMCLVEVERAPKPVASCAYPVMPGMKVKTNSPLVHKAREGVMEFLLYNHPLDCPICDQGGECDLQDQSMRYGTDRGRFSEPTGKRSVEDKNFGPLINTEMTRCIQCTRCVRFANEVAGATELGTSGRGNDMQISTYIEKTIDSEMSGNVIDLCPVGALTSKPYNMKARPWELKKYETIDVSDAIGSNIRLDTRGVEVMRILPRLNEEVNEEWISDKTRFFYDGLKVQRLTTPLIREGDRFVPATWEKALKRVGQELGRVQGNSAKAIAGHLADAESMVALKDLLNRVGSDNLAIDAPNGSKPLAIQADFRSNYTLNTTIAGAEEADVVLLVGTNPRHEAPILNTRFRKAYLHNGQDLGLIGQADDLNYEYAHIGESSKDIEKILDGSHPFAKRLAEAKRPMIVVGSSVVENAKDSEYLLSKVSELSEKFKNTLFQDGWNGVNVLQRAASRTAAYEIGFVPTSTEASSTSAKFLYLLNADEITASDVPKDAFVVYQGHHGDVGAQYADVILPGSAFTEKNATYVNTEGRTQITRAGVNPPAAAREDWKIIRALSEVAGYTLPYDDLPSVRARLSDISPALTRYDVIETPSISQIGLTAQRKPNAQSTGEVLTSVIKNFYRTDPISRASSTMAKCTKTWVAGKDVEAELKAATA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NM91</accession>
    <name>A0A1C7NM91_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Sterol regulatory element-binding protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">sre1_0</name>
        <name evidence="3" type="ORF">A0J61_01831</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000063">
        <property type="protein sequence ID" value="OBZ90110.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NM91"/>
    <dbReference type="STRING" id="101091.A0A1C7NM91"/>
    <dbReference type="InParanoid" id="A0A1C7NM91"/>
    <dbReference type="OrthoDB" id="2133190at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.280.10">
        <property type="entry name" value="Helix-loop-helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011598">
        <property type="entry name" value="bHLH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036638">
        <property type="entry name" value="HLH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052099">
        <property type="entry name" value="Regulatory_TF_Diverse"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47336">
        <property type="entry name" value="TRANSCRIPTION FACTOR HMS1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47336:SF2">
        <property type="entry name" value="TRANSCRIPTION FACTOR HMS1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00010">
        <property type="entry name" value="HLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00353">
        <property type="entry name" value="HLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47459">
        <property type="entry name" value="HLH, helix-loop-helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50888">
        <property type="entry name" value="BHLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BHLH" evidence="2">
        <location>
            <begin position="263"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="107"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="300"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="381"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="119"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="146"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="311"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="385"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="405"/>
            <end position="418"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50888"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ90110.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="1115" mass="125956" checksum="B8C2315301E060D9" modified="2016-11-30" version="1">MEAFAPLSLDLFAEANGGLDEEQSNFFSLSQFDMELQQQAQAALQQESWQDFDKYLAVDNQLFNTATNMARSQEAQPIFVNNDTMSGNNFNDQSTMLYEPLANLLPPSQEQPKALFDPNWNNNSSNENNNNMNFKNEYASPESLPYSPPHNPQPNPSLSSTSGQPDIALFQPAVEDKTTMNSVQTPTSILDSTNWNSPSIAPPFDSAQGIKRKKKEIGLTNQILLTISFIAKVPIQRLKTNSIINNAVNAALNTSTPPVGRQHKKTAHNAIERRYRNNINDRIAELKNAVPALLYAKVKDNRSGKRAHRDDEDDEGEDGEEFLDGVAVATKLNKATILRKATEYINHLKKTGEDIRRENQTLQHILSQLPGGQDVLQRYHMQKQQQEKETREQQLLERQMQKQKEHQRKLANRKRARHNNNSSHENSDEYESSSSSPGSFDPVTPPAMANRVFMALFMCITFFSTSPLTTGPTSEKYPEHHHISRTAPITDNSQSTQSLNHASSASGSYFALFESSGIWSIVRTVIFVVCITQLVLPYLKSMFIGSSLKLKRVQKFKRTTSSVRKEILNSTVTPGDLKCKQVYSLLEKSIKSQDNDDLPSNSFSLFFSLLREIVRVFSRHVLGYEIMYGDQDDVLPEEEWAKVCRWIKLNETRCVGGSSHNSRMFSVYSCLRMINLVDVLEDDIHDNTNQIHARAYATAAMQMLLAVPRLSVAEKLFSYFWQHAVDSSKHSHHQDDGVLEESDLWMQSLAWTDPEQKYDLTEEIRLSRAWSEAIEILQNQNSIRGDSSHPSNQPILSLSYTAPVTVPVAILSTLHLLDHLCTQFDRLISNFTLRSESRNLNNNSRIETAFVDIMLLAGPASPESDDNANQQRLAHWLSTVGAIAEALWKNDLEQVEKWLPSLMQRVPRSMTCKAATVSQKATLNQLDELTKKTMIHVLVGAALLKNTDVEKQKQGLAELENAEALRLVTRKLQNKLRSANIGYEDEEASLECTAMAFAEFVVSFVSLESWINAMTLDISPEKEILIDEEIREATLNLRRMIRFPCLQTLSQNQFIIDRLSRLGRFIAHHSGDADSACDLSDSEDLNHLLTEEKMNSRQLCIKKADKAHSILHGLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NMC2</accession>
    <name>A0A1C7NMC2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Glyceraldehyde-3-phosphate dehydrogenase</fullName>
            <ecNumber evidence="12">1.2.1.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">GPD1_1</name>
        <name evidence="14" type="ORF">A0J61_03537</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>D-glyceraldehyde 3-phosphate + phosphate + NAD(+) = (2R)-3-phospho-glyceroyl phosphate + NADH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:10300"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57604"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
            <dbReference type="EC" id="1.2.1.12"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 12">Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 1/5.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3 12">Homotetramer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.2.1.12" evidence="12"/>
    <dbReference type="EMBL" id="LUGH01000154">
        <property type="protein sequence ID" value="OBZ88414.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NMC2"/>
    <dbReference type="FunCoup" id="A0A1C7NMC2">
        <property type="interactions" value="398"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NMC2"/>
    <dbReference type="InParanoid" id="A0A1C7NMC2"/>
    <dbReference type="OrthoDB" id="1152826at2759"/>
    <dbReference type="UniPathway" id="UPA00109">
        <property type="reaction ID" value="UER00184"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004365">
        <property type="term" value="F:glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006006">
        <property type="term" value="P:glucose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006096">
        <property type="term" value="P:glycolytic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd18126">
        <property type="entry name" value="GAPDH_I_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd05214">
        <property type="entry name" value="GAPDH_I_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.360.10:FF:000001">
        <property type="entry name" value="Glyceraldehyde-3-phosphate dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000266">
        <property type="entry name" value="Glyceraldehyde-3-phosphate dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.360.10">
        <property type="entry name" value="Dihydrodipicolinate Reductase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020831">
        <property type="entry name" value="GlycerAld/Erythrose_P_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020830">
        <property type="entry name" value="GlycerAld_3-P_DH_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020829">
        <property type="entry name" value="GlycerAld_3-P_DH_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020828">
        <property type="entry name" value="GlycerAld_3-P_DH_NAD(P)-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006424">
        <property type="entry name" value="Glyceraldehyde-3-P_DH_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01534">
        <property type="entry name" value="GAPDH-I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10836">
        <property type="entry name" value="GLYCERALDEHYDE 3-PHOSPHATE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10836:SF76">
        <property type="entry name" value="GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02800">
        <property type="entry name" value="Gp_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00044">
        <property type="entry name" value="Gp_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000149">
        <property type="entry name" value="GAP_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00078">
        <property type="entry name" value="G3PDHDRGNASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00846">
        <property type="entry name" value="Gp_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55347">
        <property type="entry name" value="Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00071">
        <property type="entry name" value="GAPDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 12" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="5 9 12" id="KW-0520">NAD</keyword>
    <keyword evidence="9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4 12" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding" evidence="13">
        <location>
            <begin position="3"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="7">
        <location>
            <position position="152"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="12"/>
            <end position="13"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="35"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="80"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="122"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="151"/>
            <end position="153"/>
        </location>
        <ligand>
            <name>D-glyceraldehyde 3-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="182"/>
        </location>
        <ligand>
            <name>D-glyceraldehyde 3-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="211"/>
            <end position="212"/>
        </location>
        <ligand>
            <name>D-glyceraldehyde 3-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="234"/>
        </location>
        <ligand>
            <name>D-glyceraldehyde 3-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="316"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="site" description="Activates thiol group during catalysis" evidence="10">
        <location>
            <position position="179"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004869"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007406"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR000149-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR000149-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR000149-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR000149-4"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU000397"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU361160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="SMART" id="SM00846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="OBZ88414.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="338" mass="36024" checksum="AAD565C8B82D8C02" modified="2016-11-30" version="1">MVVKAGINGFGRIGRIVLRASQDKKEDVQVVHINDPFITLDYMVYMLKYDTVHGRFDGTVEAKDGKLVVNGQAISVSAERDPSQIPWGQSGAEYIIESTGVFTTTEGAEAHLKGGAKKVIISAPSKDAPMFVCGVNLDAYKSEYKVISNASCTTNCLAPLAKVINDNFGITEGLMTTVHATTATQKTVDGPSHKDWRGGRAAASNIIPSSTGAAKAVGKVIPELNGKLTGMAFRVPTPDVSVVDLTVNLAKEASYDEIKQVIKKASEGPMKGILGYTEDAVVSTDFVGEPHSSVFDAAAGIQLSPKFVKLIAWYDNEFGYSKRVVDLLVHAAKVDGAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NMD4</accession>
    <name>A0A1C7NMD4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Vacuolar amino acid transporter 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">avt3_2</name>
        <name evidence="8" type="ORF">A0J61_01766</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the amino acid/polyamine transporter 2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000060">
        <property type="protein sequence ID" value="OBZ90178.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NMD4"/>
    <dbReference type="STRING" id="101091.A0A1C7NMD4"/>
    <dbReference type="InParanoid" id="A0A1C7NMD4"/>
    <dbReference type="OrthoDB" id="1684102at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005774">
        <property type="term" value="C:vacuolar membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015179">
        <property type="term" value="F:L-amino acid transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1740.10">
        <property type="entry name" value="Amino acid/polyamine transporter I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013057">
        <property type="entry name" value="AA_transpt_TM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22950">
        <property type="entry name" value="AMINO ACID TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22950:SF666">
        <property type="entry name" value="VACUOLAR AMINO ACID TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01490">
        <property type="entry name" value="Aa_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="47"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="73"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="115"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="158"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="187"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="225"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="258"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="301"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="346"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="371"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="403"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="domain" description="Amino acid transporter transmembrane" evidence="7">
        <location>
            <begin position="41"/>
            <end position="424"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008066"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OBZ90178.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="445" mass="48729" checksum="868AAF5EF7704AB1" modified="2016-11-30" version="1">MNQTEKVLAGPQSTIHEKYHQEDQYENSLMEEQIEHVPEGTASPGKALFMLLKAFIGTGVIFLPGSFLSGGLILSIVLMILLASICCIAFQILVKAQQAIGGSYGDVAEHLYGPYLKHLIQFFLCISQVGFVCSYMIFISENIGIVVNTVNNCNSPFAPKYYIWIILAVIIPLCWVRKIAKLSPTAIIGDIFIAFGLICVLYFCSSQIHDHGVGPNLVMVNQNTFGLMIGTAIFSYEGIGMVLPIVNGMKDPKKFPLVLNLGMLICAIVFTLIGSIGYIAYGETTQASVVANIPRAPLSTTVQVLYAIAMIFSCPFMLYPPLTIIEKYVFGERSGTKSQKIKWGKNFVRSLIPLICAVISFGVGSENLSKFVSLVGSVACMPLCFIFPGLFHFKITTRKVAKVFDMGLVFFGLLCMGYTLYVNINSWVHPAETTGSVIDMNNCSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NN28</accession>
    <name>A0A1C7NN28_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_01452</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000046">
        <property type="protein sequence ID" value="OBZ90495.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NN28"/>
    <dbReference type="InParanoid" id="A0A1C7NN28"/>
    <dbReference type="OrthoDB" id="2278190at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008889801" evidence="2">
        <location>
            <begin position="17"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="151"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="154"/>
            <end position="163"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ90495.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="282" mass="30914" checksum="64C32E3B2F7F1803" modified="2016-11-30" version="1">MKFITSALLAISAVSAAIIAPRQDASQDQTQQIASQYPEGTNAGLVNGTWYVTGVTDDLWDMYEKLAQTMNIQLGCLQLNNTATSATSFDGLLSAFLTHTNNANVGVNASLAGAFMLQAPDTNTNTSDRTLLWDVYGSSVYVNKDQWNQFTSEGQQQQQQDGQQGDKDVGSTTIPGFQPFQATVYSKLIDSNAQPGTNDSTNFDTVFLWSSQMRFLNPNEYQKRAGEVFGVILSRDTYLEGDKFNQTVALLPEAIAANNISIVQLNDTCRTDNNDNNNQQQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NNJ6</accession>
    <name>A0A1C7NNJ6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">PPPDE domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">A0J61_01242</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the DeSI family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000037">
        <property type="protein sequence ID" value="OBZ90702.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NNJ6"/>
    <dbReference type="FunCoup" id="A0A1C7NNJ6">
        <property type="interactions" value="117"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NNJ6"/>
    <dbReference type="InParanoid" id="A0A1C7NNJ6"/>
    <dbReference type="OrthoDB" id="412286at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0101005">
        <property type="term" value="F:deubiquitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016579">
        <property type="term" value="P:protein deubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1720.30">
        <property type="entry name" value="PPPDE domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008580">
        <property type="entry name" value="PPPDE_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042266">
        <property type="entry name" value="PPPDE_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12378">
        <property type="entry name" value="DESUMOYLATING ISOPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12378:SF80">
        <property type="entry name" value="IP06716P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05903">
        <property type="entry name" value="Peptidase_C97"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01179">
        <property type="entry name" value="DUF862"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51858">
        <property type="entry name" value="PPPDE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PPPDE" evidence="5">
        <location>
            <begin position="21"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="166"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="169"/>
            <end position="184"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51858"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OBZ90702.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="260" mass="29088" checksum="A2B96E278A557C74" modified="2016-11-30" version="1">MLNLIRNALNKTEVDSEQEKRRIVLNVYDMLQPGFLTNLGFFLGIGIYHSGIEIGDNEYCFGGHDYEHVTGVFMVKPRVGPQGLLFKQSIHMGYTNLSQKEIDQVLQDISKEYVGTSYKLLTRNCNHFSEDLCKRLTGRTAPGWINRAAKLGTMFPCVIPTEWIEPPDADTSSPSSSSVASNVPLQHNKKSSPPPIHTDNKRKSANRRHSSSTDSIKLVRTPVLEHDELDCSSPVKEPDTHRPEVIRSATQVSMTAPVQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-06-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NNT9</accession>
    <name>A0A1C7NNT9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_01268</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000038">
        <property type="protein sequence ID" value="OBZ90668.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NNT9"/>
    <dbReference type="InParanoid" id="A0A1C7NNT9"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ90668.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="95" mass="10758" checksum="0A3DCBB4DD57D545" modified="2016-11-30" version="1">MTKILREDDAKATQRRRDGSYLLKIQLSCSSNATMEQAPPWIESLLGVSKGSRTISSEEQVVPEEEVSQKGQIFVQGLVWLLKTGEWLSTRHQLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NNV7</accession>
    <name>A0A1C7NNV7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Cell division control protein 15</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">cdc15_1</name>
        <name evidence="11" type="ORF">A0J61_02993</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000122">
        <property type="protein sequence ID" value="OBZ88954.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NNV7"/>
    <dbReference type="STRING" id="101091.A0A1C7NNV7"/>
    <dbReference type="InParanoid" id="A0A1C7NNV7"/>
    <dbReference type="OrthoDB" id="27823at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032153">
        <property type="term" value="C:cell division site"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043226">
        <property type="term" value="C:organelle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007010">
        <property type="term" value="P:cytoskeleton organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00174">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.60">
        <property type="entry name" value="Arfaptin homology (AH) domain/BAR domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.40">
        <property type="entry name" value="SH3 Domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027267">
        <property type="entry name" value="AH/BAR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031160">
        <property type="entry name" value="F_BAR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036028">
        <property type="entry name" value="SH3-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001452">
        <property type="entry name" value="SH3_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23065:SF7">
        <property type="entry name" value="NOSTRIN, ISOFORM H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23065">
        <property type="entry name" value="PROLINE-SERINE-THREONINE PHOSPHATASE INTERACTING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14604">
        <property type="entry name" value="SH3_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00326">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103657">
        <property type="entry name" value="BAR/IMD domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50044">
        <property type="entry name" value="SH3-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51741">
        <property type="entry name" value="F_BAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50002">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="11" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="11" id="KW-0132">Cell division</keyword>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="4" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0728">SH3 domain</keyword>
    <feature type="domain" description="F-BAR" evidence="10">
        <location>
            <begin position="1"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="domain" description="SH3" evidence="9">
        <location>
            <begin position="767"/>
            <end position="831"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="294"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="366"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="438"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="509"/>
            <end position="532"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="643"/>
            <end position="684"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="306"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="374"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="387"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="408"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="452"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="509"/>
            <end position="518"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="520"/>
            <end position="529"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="647"/>
            <end position="663"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="674"/>
            <end position="684"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="OBZ88954.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="834" mass="94406" checksum="A8B1CAE742636807" modified="2016-11-30" version="1">METTARAHIDLAQQLKDHLEAPLDGFLKDQREIRRMQQQQIESSKQLKGLHKSDVLRAKEVYATECQKLISLDQQAESTPLEEILKEIEEQKRMVTVADQVYRRSVENYNAMNEKFVNDWTVSANKFQEMEVKRITYLRSTLWSFANMMTSTFSIDEECCDRLRTALEITDVEKDMTHFVNKYATGSNLPQPMVCETLYDPALLVQTTPSSSIHSLMDKKRLELQNHPHQDLLQQKVEHTEQMEQPRSLPIDEARAERIVLTRNADSNLTNPDEELKSIDHQLQKIEIQNTSLDMVPDQPPQSSHSNDKAYKEVEQMLSSQPQEKTVVDQATPPSALQTAYTQDSQPLLGEFSTGIYNVLGLKDNEDHARPQHNPVSSAQETNTMKPMDEAKADKKYQPKPNPGYHPNTDQPETISSHPVANISPRGSSLLVNEQKLLEKPTRANGHYSIEENTEEEEGQKEEEYQSRIPKLPTKDEKWVISSIRRPQQLPVKTQHATMYDGSVRSSSIISNSASPVPHKQLDEGETKHQPKVHKPVVPLTIEIPNAVKTPADMAQQIIQEGRKQIKMSPVQPDHFHQEQHPNGALEENGMGIRPAPWQEEFKSNDHVIKNAGYRGPPMMATNTNAAMPAAAYYSYQQPARASVFRQEPHSHEPQQAHDDSANKKRFGVKNQLPPLSNTKQNGEATLKTAASNLKDKEKGRFSLGFFGGNKKEKKKEKEAAANAAVIASYQQQQPRPTSQVIYAGSHESFDSSNMTKQSNAYAAETRFISYAKAQWPFEATIEGEMSFHQDEVLGVIRKQTDGWWEAERIGAVNTGQRGLIPGNYMQDNYPAPN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NPH2</accession>
    <name>A0A1C7NPH2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_00938</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000025">
        <property type="protein sequence ID" value="OBZ91007.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NPH2"/>
    <dbReference type="STRING" id="101091.A0A1C7NPH2"/>
    <dbReference type="InParanoid" id="A0A1C7NPH2"/>
    <dbReference type="OrthoDB" id="2224620at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="119"/>
            <end position="143"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ91007.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="453" mass="51007" checksum="3A151D743E930A84" modified="2016-11-30" version="1">MVIERFSLVFLVFLSFLVVSHIYHLAHYGYSIGGKTHHGFLDYPNEIASADAIKLSRFMESLHTLWQLDERVKKPFDREIERHQEPYWAKEIDVKDLNKRHQVIQTIAQEVLGILPPPSSSLARPPLHSPRETGNQAGIPKLNHKIVNPPEELKIKRPLRPHHPVSPECGHLPYEKQKMLSFSPQEFKTLHMKLDGLFSEGGLIHLRSSPDSDDIRIQLKLFAQREDLFTHVLLSEDNHTSSKFKTVHINHHHPSILKSCMVYQLDIIFPSSLTDYEDLNIKVNHASQIEGDLGNTVLNKFSVGLGRGAIKLKGIKAKELMLGTLNGIILGSYHPLNTFGAATVVGATKIELFPTSQGVKSTVVALDGPVKAIVSLPNKETNIGYTAHCWLCDPEIVPLQRPKDLHLTSSKRSTIKMGHFGELRGQGYINVHSRHGESKLIIDVLPERDRLVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NQB7</accession>
    <name>A0A1C7NQB7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Protein sum2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">sum2_1</name>
        <name evidence="6" type="ORF">A0J61_00654</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000015">
        <property type="protein sequence ID" value="OBZ91315.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="FunCoup" id="A0A1C7NQB7">
        <property type="interactions" value="274"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NQB7"/>
    <dbReference type="InParanoid" id="A0A1C7NQB7"/>
    <dbReference type="OrthoDB" id="21539at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000932">
        <property type="term" value="C:P-body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033962">
        <property type="term" value="P:P-body assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034063">
        <property type="term" value="P:stress granule assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01736">
        <property type="entry name" value="LSm14_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025762">
        <property type="entry name" value="DFDF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019050">
        <property type="entry name" value="FDF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025761">
        <property type="entry name" value="FFD_box"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025609">
        <property type="entry name" value="Lsm14-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010920">
        <property type="entry name" value="LSM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047575">
        <property type="entry name" value="Sm"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13586">
        <property type="entry name" value="SCD6 PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13586:SF0">
        <property type="entry name" value="TRAILER HITCH, ISOFORM H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12701">
        <property type="entry name" value="LSM14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01199">
        <property type="entry name" value="FDF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01271">
        <property type="entry name" value="LSM14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50182">
        <property type="entry name" value="Sm-like ribonucleoproteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51512">
        <property type="entry name" value="DFDF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51513">
        <property type="entry name" value="FFD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52002">
        <property type="entry name" value="SM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Sm" evidence="5">
        <location>
            <begin position="1"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="domain" description="DFDF" evidence="3">
        <location>
            <begin position="333"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="domain" description="FFD box profile" evidence="4">
        <location>
            <begin position="376"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="92"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="275"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="355"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="391"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="FFD box" evidence="1">
        <location>
            <begin position="376"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="391"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="414"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="426"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="444"/>
            <end position="455"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51512"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS52002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OBZ91315.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="455" mass="51102" checksum="61CAD5A7F469C707" modified="2016-11-30" version="1">MSGQNYIGSKISLISLSDIRYVGVLHNINPVDSTVSLQKGICYQTTVRSFGTEGRKGNPSEEIPASDNVFDYVVFRGTDIKDLQVFEAPPSFQPSSSSQQMYEPISEPTSGVNQSQYYLNKPYEPNMAYAYENNYWQYAAYPTQQPNHLYQLSQHQFQQQPQLEPSSQVGLKMPVPEDYQGITENNAMASSSPETKTSNTINGNDAYKTEEKTIVSTPKEXVDVSSLESSLIQGKKVIEEKNTDDILVDALVKQVSELDIKQPYFSKQNKAIKPLQQKNKESGKKHTKRVNNKQAHPKSVAVVSTDASSPSKARRNSNNINKDNEKNPGHVRHNSRGILVPKSDFDFASANAKFNKNSDSLDENDTNAQASIGSDHFYDKKKSFFDDISCESKERQNGHRGGKYKEESKLNLETFGQATLSGQSAKRSRLRHRENRGKGRSKHQNSEQNKKEIKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NQD0</accession>
    <name>A0A1C7NQD0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Abhydrolase domain-containing protein C22H12.03</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">A0J61_02481</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the AB hydrolase superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000094">
        <property type="protein sequence ID" value="OBZ89474.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NQD0"/>
    <dbReference type="FunCoup" id="A0A1C7NQD0">
        <property type="interactions" value="337"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NQD0"/>
    <dbReference type="InParanoid" id="A0A1C7NQD0"/>
    <dbReference type="OrthoDB" id="8119704at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052689">
        <property type="term" value="F:carboxylic ester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1820:FF:000039">
        <property type="entry name" value="Esterase ybfF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46118">
        <property type="entry name" value="PROTEIN ABHD11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46118:SF4">
        <property type="entry name" value="PROTEIN ABHD11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="3">
        <location>
            <begin position="33"/>
            <end position="272"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008645"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OBZ89474.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="286" mass="32877" checksum="BAA51EEBEA2951C2" modified="2016-11-30" version="1">MFKVWPIVQKRSFKTVPLAFAKYSADEQIKSNKPLIICHGLFGSKQNWRSLARSLSQSCQRDVYAIDARNHGESPHAHEHHYEAISHDILEFIQHHQLHQPILLGHSMGGKAMMYVALQQPELVSKLIVVDIAPVHSPLTREYHDHIRIMREIQSRRLTRQKEADDILKTVEPDVAVRQFLLTNLKKNKSDGVYQFRVPLTILENALGHLGEFRPKLKKKGVYQGPTLFITGDQSPFRKPFLRMPSLVPSYFPNATVVTVKEAGHWVQAEKPDEFLSLTTEFILQH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NQU8</accession>
    <name>A0A1C7NQU8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Serine aminopeptidase S33 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_01138</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000033">
        <property type="protein sequence ID" value="OBZ90796.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NQU8"/>
    <dbReference type="STRING" id="101091.A0A1C7NQU8"/>
    <dbReference type="InParanoid" id="A0A1C7NQU8"/>
    <dbReference type="OrthoDB" id="408373at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050266">
        <property type="entry name" value="AB_hydrolase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022742">
        <property type="entry name" value="Hydrolase_4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43798:SF33">
        <property type="entry name" value="HYDROLASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G14860)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43798">
        <property type="entry name" value="MONOACYLGLYCEROL LIPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12146">
        <property type="entry name" value="Hydrolase_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Serine aminopeptidase S33" evidence="1">
        <location>
            <begin position="23"/>
            <end position="276"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ90796.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="289" mass="32577" checksum="5218CB6964BF3144" modified="2016-11-30" version="1">MAVLLKSGNMQLNYEVLGLSNSESKPLILLFHGAGGDLHHYDNVTHKLVKKGYRVLLMDIRHHGLSQPISKAEPVTFDFDDVLKDVDQVLTHVVQQHYTSKKTHSLYVGGLSMGGMIALMFGEEKAKVNYKWNKMELKGLVLMASAVPGMQIERSGWDAFRDRTATLDYLQWSKQAIIQSSITKRGQTETARALGLISDKALYECMVNIALQLPNPTDPPVAYKPRVCLPMLLLMPEQDPLTRPEMELLHKINRQNNIPSRFVLVPNSGHMVILDQSEAVYKQIHKFCS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NQY7</accession>
    <name>A0A1C7NQY7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_00601</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000014">
        <property type="protein sequence ID" value="OBZ91339.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NQY7"/>
    <dbReference type="InParanoid" id="A0A1C7NQY7"/>
    <dbReference type="OrthoDB" id="2274292at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="50"/>
            <end position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ91339.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="99" mass="11273" checksum="857FE8955A4A6BD6" modified="2016-11-30" version="1">MGKSAKFYKRPSKKEKEGIALKKLVEPTAISKKKAAKETKTISVPVEMFKSQKAEQQDNDIDMDSKPVVKKKQKEAELPDYVDLFSGKKTYKKIPGKRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NSC2</accession>
    <name>A0A1C7NSC2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein UNK4.09</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_00009</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000001">
        <property type="protein sequence ID" value="OBZ91929.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NSC2"/>
    <dbReference type="FunCoup" id="A0A1C7NSC2">
        <property type="interactions" value="186"/>
    </dbReference>
    <dbReference type="InParanoid" id="A0A1C7NSC2"/>
    <dbReference type="OrthoDB" id="74240at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.250.10">
        <property type="entry name" value="Rhodanese-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036873">
        <property type="entry name" value="Rhodanese-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52821">
        <property type="entry name" value="Rhodanese/Cell cycle control phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ91929.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="300" mass="35272" checksum="A8A870C2A603ACD9" modified="2016-11-30" version="1">MNRLYAWKNSQLPHLCLDLRTQAQYNACHLIPSTNIPFSQLVVRQAELPPKYMPMAVLHTHDTTHAIDWLIQRGWHCPFVIPEEALDWKQLIEQRWAASCDGRDNQKWVLFQPSPFLKKHISYLEAKIERPTRTCLDMGCGAGRDISWIVSTRQHWRATAFDSQPGAIQRMTQLVHYLNIQDRVQIGQVKFQHNQTWKWISKPVPIQTYDLVLNIRFLSRPFWYKVPSLLNKGGCFVLSQFLHDDDLCVYDQPKRSHRLEKGEIEEVFGQMEDMEIIMNEIEKTEDGRPLQCVIIKRINP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NVG4</accession>
    <name>A0A1C7NVG4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Putative low-specificity L-threonine aldolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">gly1_1</name>
        <name evidence="7" type="ORF">A0J61_00514</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the threonine aldolase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000011">
        <property type="protein sequence ID" value="OBZ91464.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NVG4"/>
    <dbReference type="FunCoup" id="A0A1C7NVG4">
        <property type="interactions" value="397"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NVG4"/>
    <dbReference type="InParanoid" id="A0A1C7NVG4"/>
    <dbReference type="OrthoDB" id="10261951at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008732">
        <property type="term" value="F:L-allo-threonine aldolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006545">
        <property type="term" value="P:glycine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006567">
        <property type="term" value="P:L-threonine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.640.10:FF:000030">
        <property type="entry name" value="Low-specificity L-threonine aldolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001597">
        <property type="entry name" value="ArAA_b-elim_lyase/Thr_aldolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023603">
        <property type="entry name" value="Low_specificity_L-TA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF041359">
        <property type="entry name" value="GntG_guanitoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48097:SF9">
        <property type="entry name" value="L-THREONINE ALDOLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48097">
        <property type="entry name" value="L-THREONINE ALDOLASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01212">
        <property type="entry name" value="Beta_elim_lyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF017617">
        <property type="entry name" value="Thr_aldolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0456">Lyase</keyword>
    <keyword evidence="3" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aromatic amino acid beta-eliminating lyase/threonine aldolase" evidence="6">
        <location>
            <begin position="48"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="5">
        <location>
            <position position="243"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR017617-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OBZ91464.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="402" mass="44281" checksum="3E8D1B1104FB1E27" modified="2016-11-30" version="1">MMSFTRNLVTPLVSRRLFSTAAARPAYYTSSLLSDQHKKVDPNAKLYDFRSDTVTAPTEEMFDLMRTATRCDDVFQEDKSVNDLQDYVADLTGHEAALFCASGTMTNQLALRTHLITPPHSVVCDHRAHVFLWEAGGIAVHSRASVSPVVAANGIHVTAEEIESNLLGEDIYSAPTRVVSLENTLNGMIFPIDEIAKISTMARERGLAMHLDGARLWNAAQETGISLKEYGKHFDSMSLCLSKGVGAPIGSIVVGNAKFIDRVRFNRKLFGGGWRQSGFLAVAAQYGIDRIVPTMKETHKLAKYLADELVSMGIDLQVPTHTNMVFIDTTRVGLQIERDLIPALAERNIKMGGMGKKARLVLHHQIDRKGVDSLLEVVREAVAARQQQSNEETVRLTSSTTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MTS8</accession>
    <name>A0A1C7MTS8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_11670</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01002320">
        <property type="protein sequence ID" value="OBZ80281.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MTS8"/>
    <dbReference type="InParanoid" id="A0A1C7MTS8"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="26"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="60"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ80281.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="70" mass="7979" checksum="814A722B225EAE3A" modified="2016-11-30" version="1" fragment="single">MTSQTKQKVLQQRIKNLEDQIDALKRHKNDETQDMEGNTSTIPYPTKARKVSGNLVKRKPVTEDVKDALA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-06-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MUB8</accession>
    <name>A0A1C7MUB8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_11521</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01002143">
        <property type="protein sequence ID" value="OBZ80430.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MUB8"/>
    <dbReference type="InParanoid" id="A0A1C7MUB8"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ80430.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="55" mass="6152" checksum="B8F83160D41C555D" modified="2016-11-30" version="1" fragment="single">MDRRIPEVSASFSRPRSIRPAAPSNRVYETRMLNVESRLGVVEAFLPAAPAIRGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MV17</accession>
    <name>A0A1C7MV17_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Integrase zinc-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_11240</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001815">
        <property type="protein sequence ID" value="OBZ80711.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MV17"/>
    <dbReference type="STRING" id="101091.A0A1C7MV17"/>
    <dbReference type="InParanoid" id="A0A1C7MV17"/>
    <dbReference type="OrthoDB" id="4499277at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.340.70:FF:000001">
        <property type="entry name" value="Retrovirus-related Pol polyprotein from transposon gypsy-like Protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.340.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052160">
        <property type="entry name" value="Gypsy_RT_Integrase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041588">
        <property type="entry name" value="Integrase_H2C2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47266">
        <property type="entry name" value="ENDONUCLEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17921">
        <property type="entry name" value="Integrase_H2C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Integrase zinc-binding" evidence="1">
        <location>
            <begin position="30"/>
            <end position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF17921"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ80711.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="114" mass="13122" checksum="DE0BA0D5806757E3" modified="2016-11-30" version="1">MLLQESVKAQYKWVQNMICYQEGDVLVPVVPKTLVKAVLTKAHEDITGGNIGEEKTLKKVKQMGWWTTRKEDVTNWVRHCQACQVYKVRNISQVALMKAILPTFFSEIWAADIQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MV58</accession>
    <name>A0A1C7MV58_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_11185</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001757">
        <property type="protein sequence ID" value="OBZ80765.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MV58"/>
    <dbReference type="STRING" id="101091.A0A1C7MV58"/>
    <dbReference type="InParanoid" id="A0A1C7MV58"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="20"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="26"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="44"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="69"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ80765.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="104" mass="11486" checksum="A3FFCB823828BF01" modified="2016-11-30" version="1" fragment="single">DTAEIKLRLLRLQQKFGYKTDVMEDTSGSNHVAGLSASSDTNRYESSTSYSSYSSRRQSGLSQDYLQRETGQGESDRQQSVSALKEKIAKMKQVINSAASSPNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MVI1</accession>
    <name>A0A1C7MVI1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_11045</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001621">
        <property type="protein sequence ID" value="OBZ80905.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MVI1"/>
    <dbReference type="STRING" id="101091.A0A1C7MVI1"/>
    <dbReference type="InParanoid" id="A0A1C7MVI1"/>
    <dbReference type="OrthoDB" id="2267579at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ80905.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="229" mass="26158" checksum="B7E8DEC2EBBB7DE7" modified="2016-11-30" version="1">MHLHKKISKISRAYDNLGWLDSDSRCAAQRDPSTTDINELTAKQIQELLELSRRLKESEERAERNDRPELPNEILEELDTFANSELKNKLKKLAKGTIKYEGGRWTKSGAINKLFAPEFRKYQVEATQTVAAYHKGADRLHTTARAATEIFNDLQYVIEEGGEEKDMRNILEKARRLTIYAYATGKVLDGDARDLTTKAIRLPGSLKYLEYAEDGDKDLVFPPDIVKKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MVI9</accession>
    <name>A0A1C7MVI9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_11036</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001610">
        <property type="protein sequence ID" value="OBZ80915.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MVI9"/>
    <dbReference type="InParanoid" id="A0A1C7MVI9"/>
    <dbReference type="OrthoDB" id="2286555at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ80915.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="317" mass="35824" checksum="72EA212CF57C1879" modified="2016-11-30" version="1">MEPEGYKALKSVLSQDEMNILEASQDNKYTGLSDADMQALLKILESGGKEEIDPEAIEEEILREQLRLRSLKLKNSDQYKMLDILKCMIERVDHCNENDSELTCYRHFAKLLDCLFKDTNLLLLDGEPACIAVKEEMIAGQSLYPSSSGNVLSTCAIRKIDAIIAIEQNKERVEFSTNEWKKNNASTTTAIKQQSKNLRSNLSILNQLERKFSIRTKDILAVDFVGNLEKKEGVAVATLVEEMAVPTVKSELERAPQTINALFMLKNHVLKLAEEVASKPKRSKLRGIVRCKQPLTAPCQTPRVIFSPKLKKRKLDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MVJ6</accession>
    <name>A0A1C7MVJ6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_11060</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001634">
        <property type="protein sequence ID" value="OBZ80891.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MVJ6"/>
    <dbReference type="InParanoid" id="A0A1C7MVJ6"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ80891.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="68" mass="7939" checksum="0DCA1954812EADE4" modified="2016-11-30" version="1">MDALSESFLLKVVPLDHLTSPVATLISGCELKEYHNRVYFFWPQMNRSDLQLDQTVTAFDFDTSFFDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MVM3</accession>
    <name>A0A1C7MVM3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_11144</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001712">
        <property type="protein sequence ID" value="OBZ80808.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MVM3"/>
    <dbReference type="InParanoid" id="A0A1C7MVM3"/>
    <dbReference type="OrthoDB" id="2364331at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.160">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038425">
        <property type="entry name" value="GAT_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89009">
        <property type="entry name" value="GAT-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ80808.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="121" mass="13461" checksum="21E2EB93607A73AD" modified="2016-11-30" version="1">MSLTQVAGYTVSKTTSLNITLEEAISNSKKSSSFLLHMLVMIEPSQIKTNEIAKDAYNECVQLKEFLSEQLWSEVDDDGISSVQSALDDLNQALGKYEMTNDMIEGEWEFVESAACCVSTY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-06-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MVP5</accession>
    <name>A0A1C7MVP5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_11454</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01002049">
        <property type="protein sequence ID" value="OBZ80496.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="InParanoid" id="A0A1C7MVP5"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="84"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ80496.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="84" mass="9716" checksum="3D68621592C72FF4" modified="2016-11-30" version="1" fragment="single">MSDLPAVFCAACNVPGHSRRTYRFCRMNPRNQSDEDVHIEEGQQERTQNDVVVCSACNEPXHSRRTFAGCRMNPRFQNMEVDEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MW14</accession>
    <name>A0A1C7MW14_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">OTU domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_11314</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001900">
        <property type="protein sequence ID" value="OBZ80636.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MW14"/>
    <dbReference type="STRING" id="101091.A0A1C7MW14"/>
    <dbReference type="InParanoid" id="A0A1C7MW14"/>
    <dbReference type="OrthoDB" id="2379842at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd22744">
        <property type="entry name" value="OTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ80636.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="161" mass="17888" checksum="0E6CD708EE4F8A59" modified="2016-11-30" version="1">MIKQEKDHRFASQISVEIPANAFTGIVDVKPDGFCGFRALAAQIFDDENEFLEAFGQLYDLKACKRIICFGIDEKVGSKKTAMDANTLVENRFWFLALECAQIAACTFGVPVAVYDSDNGNLIFLPVFDKFNCVNFKVIATVIATSTPPRMHISHVILSQI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MWC1</accession>
    <name>A0A1C7MWC1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_11195</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001765">
        <property type="protein sequence ID" value="OBZ80756.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MWC1"/>
    <dbReference type="InParanoid" id="A0A1C7MWC1"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ80756.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="241" mass="27456" checksum="A1C66780F8E6BA9D" modified="2016-11-30" version="1">MGNRASNKVESNYSGIKCHNKISSGKLANELKEGCVIFAHCFFSQTKGLYCNRRTVRKLLFKTILKNETSHAVGAKMSGLKGKIISFPLEPKPTLTMPFIIHVRCVKPTIFHVDIVLRNTKALFLWQPFIKDSTFCTKMIEQASKRTSLNSIKLSSHLTADLRIEGERVSLEDNSRALFNKYPKGKQTKRALPSPVVYDIKGDLKSTTREKVALEREVERIVQLPKIKFSRKDIMKNKSRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-06-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MXG9</accession>
    <name>A0A1C7MXG9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_10501</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001202">
        <property type="protein sequence ID" value="OBZ81451.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MXG9"/>
    <dbReference type="InParanoid" id="A0A1C7MXG9"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ81451.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="53" mass="5561" checksum="73585C6C4EB23793" modified="2016-11-30" version="1" fragment="single">SASEVSMASASEVSMASASEVSMASASEMALEGAVWIADSQAEARFQGYNWRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MXV2</accession>
    <name>A0A1C7MXV2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 7">Arabinan endo-1,5-alpha-L-arabinosidase</fullName>
            <ecNumber evidence="4 7">3.2.1.99</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">abnB</name>
        <name evidence="11" type="ORF">A0J61_10290</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>Endohydrolysis of (1-&gt;5)-alpha-arabinofuranosidic linkages in (1-&gt;5)-arabinans.</text>
            <dbReference type="EC" id="3.2.1.99"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 7">Glycan metabolism; L-arabinan degradation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 7">Belongs to the glycosyl hydrolase 43 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.99" evidence="4 7"/>
    <dbReference type="EMBL" id="LUGH01001105">
        <property type="protein sequence ID" value="OBZ81660.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MXV2"/>
    <dbReference type="STRING" id="101091.A0A1C7MXV2"/>
    <dbReference type="InParanoid" id="A0A1C7MXV2"/>
    <dbReference type="OrthoDB" id="195678at2759"/>
    <dbReference type="UniPathway" id="UPA00667"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046558">
        <property type="term" value="F:arabinan endo-1,5-alpha-L-arabinosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031222">
        <property type="term" value="P:arabinan catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd08998">
        <property type="entry name" value="GH43_Arb43a-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.115.10.20">
        <property type="entry name" value="Glycosyl hydrolase domain, family 43"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050727">
        <property type="entry name" value="GH43_arabinanases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006710">
        <property type="entry name" value="Glyco_hydro_43"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016840">
        <property type="entry name" value="Glyco_hydro_43_endo_a_Ara-ase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023296">
        <property type="entry name" value="Glyco_hydro_beta-prop_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43301">
        <property type="entry name" value="ARABINAN ENDO-1,5-ALPHA-L-ARABINOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43301:SF3">
        <property type="entry name" value="ARABINAN ENDO-1,5-ALPHA-L-ARABINOSIDASE A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04616">
        <property type="entry name" value="Glyco_hydro_43"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF026534">
        <property type="entry name" value="Endo_alpha-L-arabinosidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75005">
        <property type="entry name" value="Arabinanase/levansucrase/invertase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="5 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="10">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008889362" description="Arabinan endo-1,5-alpha-L-arabinosidase" evidence="10">
        <location>
            <begin position="20"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="8">
        <location>
            <position position="36"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="8">
        <location>
            <position position="193"/>
        </location>
    </feature>
    <feature type="site" description="Important for catalytic activity, responsible for pKa modulation of the active site Glu and correct orientation of both the proton donor and substrate" evidence="9">
        <location>
            <position position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004834"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012586"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRNR" id="PIRNR026534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR606710-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR606710-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="OBZ81660.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="313" mass="34282" checksum="EFF41A30AA6D923B" modified="2016-11-30" version="1">MKKTSLALLLQLFVTQISAAWPPAPGPVKGDIYVHDPAMIKRGSNYYLFGTHDDVNIKKSSDRTNFKSVGAAVPWMGKTDVWAPDVSEHNGQYWLYYSTSTFGTQNSCIYMATSSTLEPGSYSNKGQVICSKKGDPYNAIDPNFVRDVKGNNWLSFGSFYGGIYVVQLDGTGKVKSGAKPTLIAKRAFPDAMEGPFIYVKNNMYYLFTSWGNCCVDPTNVKEKSSEPYHIKVCRAKSITGPYVDAAGAACTNGGGLEVLKGQSGIWGVGGQGVMKDGNQDVLYYHYYDSKSNYAAKLGVNLLKWDSNGWPVAY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MY30</accession>
    <name>A0A1C7MY30_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Anthranilate phosphoribosyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">trp4</name>
        <name evidence="4" type="ORF">A0J61_10239</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001083">
        <property type="protein sequence ID" value="OBZ81708.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MY30"/>
    <dbReference type="FunCoup" id="A0A1C7MY30">
        <property type="interactions" value="487"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7MY30"/>
    <dbReference type="InParanoid" id="A0A1C7MY30"/>
    <dbReference type="OrthoDB" id="427800at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004048">
        <property type="term" value="F:anthranilate phosphoribosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000162">
        <property type="term" value="P:L-tryptophan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1030.10">
        <property type="entry name" value="Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005940">
        <property type="entry name" value="Anthranilate_Pribosyl_Tfrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000312">
        <property type="entry name" value="Glycosyl_Trfase_fam3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035902">
        <property type="entry name" value="Nuc_phospho_transferase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01245">
        <property type="entry name" value="trpD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43285">
        <property type="entry name" value="ANTHRANILATE PHOSPHORIBOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43285:SF2">
        <property type="entry name" value="ANTHRANILATE PHOSPHORIBOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00591">
        <property type="entry name" value="Glycos_transf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52418">
        <property type="entry name" value="Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 4" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glycosyl transferase family 3" evidence="3">
        <location>
            <begin position="1"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00591"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OBZ81708.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="231" mass="25194" checksum="D0C5DEE2B8C22D81" modified="2016-11-30" version="1" fragment="single">NRAASSKSGSADLMEAHGCQIAQVQPEQVASILHKTNFCFLFSQTYHPAMKHVASIRKEMGIPTVFNLLGPMSNPAKPTRVIVGVHSPEIGSLMANALRLTGVQQALVVCGAERLDEISPAGETHYWRIHKEGDITTGTLHPTEDFGLPTHPLDQVKGGDCHENAKILKRLLNNELEEHHPILDFVLLNAAALLVVAGIATDFKEGVSRARESIQSGRAQDVLDLFRQETL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MZE4</accession>
    <name>A0A1C7MZE4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">RNA helicase</fullName>
            <ecNumber evidence="1">3.6.4.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="19" type="primary">RH35</name>
        <name evidence="19" type="ORF">A0J61_09742</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="19 20" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19 20">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.13"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the DEAD box helicase family. DDX41 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="19">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.13" evidence="1"/>
    <dbReference type="EMBL" id="LUGH01000926">
        <property type="protein sequence ID" value="OBZ82207.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MZE4"/>
    <dbReference type="STRING" id="101091.A0A1C7MZE4"/>
    <dbReference type="InParanoid" id="A0A1C7MZE4"/>
    <dbReference type="OrthoDB" id="196131at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd17951">
        <property type="entry name" value="DEADc_DDX41"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18787">
        <property type="entry name" value="SF2_C_DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000449">
        <property type="entry name" value="Probable ATP-dependent RNA helicase DDX41"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000657">
        <property type="entry name" value="Probable ATP-dependent RNA helicase DDX41"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044113">
        <property type="entry name" value="DEADc_DDX41"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014014">
        <property type="entry name" value="RNA_helicase_DEAD_Q_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001878">
        <property type="entry name" value="Znf_CCHC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036875">
        <property type="entry name" value="Znf_CCHC_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47958">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE DBP3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57756">
        <property type="entry name" value="Retrovirus zinc finger-like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51195">
        <property type="entry name" value="Q_MOTIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50158">
        <property type="entry name" value="ZF_CCHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="14" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6 19" id="KW-0347">Helicase</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 12" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="DEAD-box RNA helicase Q" evidence="18">
        <location>
            <begin position="156"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="16">
        <location>
            <begin position="187"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="17">
        <location>
            <begin position="382"/>
            <end position="545"/>
        </location>
    </feature>
    <feature type="domain" description="CCHC-type" evidence="15">
        <location>
            <begin position="555"/>
            <end position="570"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="14">
        <location>
            <begin position="68"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Q motif" evidence="13">
        <location>
            <begin position="156"/>
            <end position="184"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023594"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00047984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS51195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="OBZ82207.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="594" mass="67669" checksum="FF9DBC20BCD6A0E9" modified="2016-11-30" version="1">MSDQTNFLEEDDDYVPYVPIKQRRLDKIHKYATQRKHVEQSDHENEEEEDVILAGPKANVSLLDQKMQQKMNNTIPEKTEEEKRLEEEKRIEEAQARHKALISVQESAMGKHYTEPMKSSWEPPHYIRNMTEVDHQLIRERYHILIEGEDPVPPIRHFRDMKLPEPILKYLKSKNIEKPSPIQIQGLPVALKGRDMIGIAFTGSGKTLTFSLPLVMFALEAEVRLPLSQGEGPIGMILCPSRELARQTFDGLNSMADALARDGYPQLRSLLCIGGINMMEQNDVLRRGIHMVVATPGRLMDMLSKKKFNLDNCRYLCMDEADRMIDMGFEEDVRNIMSYFKSQRQTLLFSATMPKKIQDFALSALVKPMVVNVGRAGAANLDVIQEVEYVKQEAKMVYLLECLQKTPPPVLVFAENKNDVDDIHEYFLLKGVEAVAIHGGKTQEEREYAIQSFKDYKKDVLVATDVASKGLDFPEIKHVINFDMPKEIEDYVHRIGRTGRSGKTGVATTFINQNCSEQIRLDLKHLLKEAKQRIPPFLAAMEDPTEKYGSLTGGCSFCGGLGHRINDCPKLEQQRKQQFNSMMGGSRHADRGGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N086</accession>
    <name>A0A1C7N086_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 6">Ubiquitin-related modifier 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">Urm1</name>
        <name evidence="5" type="synonym">URM1</name>
        <name evidence="7" type="ORF">A0J61_09544</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Acts as a sulfur carrier required for 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Serves as sulfur donor in tRNA 2-thiolation reaction by being thiocarboxylated (-COSH) at its C-terminus by the MOCS3 homolog UBA4. The sulfur is then transferred to tRNA to form 2-thiolation of mcm(5)S(2)U. Prior mcm(5) tRNA modification by the elongator complex is required for 2-thiolation. Also acts as a ubiquitin-like protein (UBL) that is covalently conjugated via an isopeptide bond to lysine residues of target proteins such as AHP1. The thiocarboxylated form serves as substrate for conjugation and oxidative stress specifically induces the formation of UBL-protein conjugates.</text>
    </comment>
    <comment type="pathway">
        <text evidence="5 6">tRNA modification; 5-methoxycarbonylmethyl-2-thiouridine-tRNA biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5 6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="PTM">
        <text evidence="5">C-terminal thiocarboxylation occurs in 2 steps, it is first acyl-adenylated (-COAMP) via the hesA/moeB/thiF part of UBA4, then thiocarboxylated (-COSH) via the rhodanese domain of UBA4.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5 6">Belongs to the URM1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000874">
        <property type="protein sequence ID" value="OBZ82408.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N086"/>
    <dbReference type="FunCoup" id="A0A1C7N086">
        <property type="interactions" value="425"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N086"/>
    <dbReference type="InParanoid" id="A0A1C7N086"/>
    <dbReference type="OrthoDB" id="10248987at2759"/>
    <dbReference type="UniPathway" id="UPA00988"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042803">
        <property type="term" value="F:protein homodimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031386">
        <property type="term" value="F:protein tag activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097163">
        <property type="term" value="F:sulfur carrier activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007114">
        <property type="term" value="P:cell budding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034599">
        <property type="term" value="P:cellular response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001403">
        <property type="term" value="P:invasive growth in response to glucose limitation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032447">
        <property type="term" value="P:protein urmylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002143">
        <property type="term" value="P:tRNA wobble position uridine thiolation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd01764">
        <property type="entry name" value="Ubl_Urm1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03048">
        <property type="entry name" value="Urm1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012675">
        <property type="entry name" value="Beta-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016155">
        <property type="entry name" value="Mopterin_synth/thiamin_S_b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015221">
        <property type="entry name" value="Urm1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14986">
        <property type="entry name" value="RURM1 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09138">
        <property type="entry name" value="Urm1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037379">
        <property type="entry name" value="Ubiquitin-related_modifier_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54285">
        <property type="entry name" value="MoaD/ThiS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 5 6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 5" id="KW-1017">Isopeptide bond</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5 6" id="KW-0819">tRNA processing</keyword>
    <keyword evidence="4 5" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="modified residue" description="1-thioglycine" evidence="5">
        <location>
            <position position="104"/>
        </location>
    </feature>
    <feature type="cross-link" description="Glycyl lysine isopeptide (Gly-Lys) (interchain with K-? in acceptor proteins)" evidence="5">
        <location>
            <position position="104"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022499"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU361182"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OBZ82408.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="104" mass="11932" checksum="2877509BDB6C3664" modified="2016-11-30" version="1">MAELTINLEFSGGMELLFQNVSKHTIKFPTTNSTTGKPSNLQDLIFYIRDTMMTEKQDLFVEKDTVRPGILVLINNTDWELCDELEYELEDKDEIVFISTLHGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N0B1</accession>
    <name>A0A1C7N0B1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">TM7S3/TM198-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">A0J61_09438</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000850">
        <property type="protein sequence ID" value="OBZ82513.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N0B1"/>
    <dbReference type="STRING" id="101091.A0A1C7N0B1"/>
    <dbReference type="InParanoid" id="A0A1C7N0B1"/>
    <dbReference type="OrthoDB" id="102260at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025256">
        <property type="entry name" value="TM7S3/TM198-like_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13886">
        <property type="entry name" value="TM7S3_TM198"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="24"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="48"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="77"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="111"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="domain" description="TM7S3/TM198-like" evidence="6">
        <location>
            <begin position="2"/>
            <end position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF13886"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OBZ82513.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="159" mass="17652" checksum="815BAF3914EC53D7" modified="2016-11-30" version="1">MGFVTWVMLANFEPSSTYGVNRQTIYFIVPFVVGLVTTCFMAVTIQLYLALLGGLGGLGFGLWILGWKDGLSITSDYGRAILLTVLVVVFMVLALYSCVWHKLGAAIAGSYLFFMGLDIFFHTGFLYCFTTSLDSNHGWFKLIAGFFFSRDSNSSLRDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N0F2</accession>
    <name>A0A1C7N0F2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Karyogamy protein 5</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_09453</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000853">
        <property type="protein sequence ID" value="OBZ82501.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N0F2"/>
    <dbReference type="InParanoid" id="A0A1C7N0F2"/>
    <dbReference type="OrthoDB" id="2245566at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008889393" description="Karyogamy protein 5" evidence="1">
        <location>
            <begin position="19"/>
            <end position="385"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ82501.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="385" mass="44867" checksum="D1FFAE9BABA1B138" modified="2016-11-30" version="1">MRFNLYTIALVCLTTVYAQYPLHENIAHDIHTLKQDVQLAHPIPHVSLSLKDRVVNYVHHLHQLVAEVRYELAHNNNQRPSTQYSLDDILFSIQYYLPHAPSDPKQQETKARRRQIARILNTSPLLTRPHLTEIRNQMVDWTRTSQQLMNTHYTLPTLDSLDSLLKSAHDFVTAATDADLMVDPIFLSSGYVTLDDAVKLFLTNNRHTFDRLMQQIHQQFNDLVCLSGSLRRPLEHVRQEAMQQTRVWRDQLVTTHLEPRLQHLSWRVRNELQLMTDELRGLSPEASRVVRHHTADALLAEIDTLYDLKSAVSRAGSMIQHVWSQAGHELVLKPTSVDYWVDVMEEVKETVRHLARDLAHQQHVIQQRRKPRLHEGHKGIMRLTH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N0H7</accession>
    <name>A0A1C7N0H7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">histidine kinase</fullName>
            <ecNumber evidence="2">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">NIK1_0</name>
        <name evidence="14" type="ORF">A0J61_09443</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="2"/>
    <dbReference type="EMBL" id="LUGH01000851">
        <property type="protein sequence ID" value="OBZ82508.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N0H7"/>
    <dbReference type="STRING" id="101091.A0A1C7N0H7"/>
    <dbReference type="InParanoid" id="A0A1C7N0H7"/>
    <dbReference type="OrthoDB" id="10266508at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071474">
        <property type="term" value="P:cellular hyperosmotic response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06225">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="CDD" id="cd16922">
        <property type="entry name" value="HATPase_EvgS-ArcB-TorS-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd17546">
        <property type="entry name" value="REC_hyHK_CKI1_RcsC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.565.10:FF:000010">
        <property type="entry name" value="Sensor histidine kinase RcsC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.130:FF:000002">
        <property type="entry name" value="Two-component osmosensing histidine kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.120.1530:FF:000002">
        <property type="entry name" value="Two-component osmosensing histidine kinase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1530">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="entry name" value="Histidine kinase-like ATPase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003660">
        <property type="entry name" value="HAMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45339">
        <property type="entry name" value="HYBRID SIGNAL TRANSDUCTION HISTIDINE KINASE J"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45339:SF1">
        <property type="entry name" value="HYBRID SIGNAL TRANSDUCTION HISTIDINE KINASE J"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00672">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00304">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="CheY-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="Homodimeric domain of signal transducing histidine kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF58104">
        <property type="entry name" value="Methyl-accepting chemotaxis protein (MCP) signaling domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50885">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7 14" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3 10" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="9" id="KW-0902">Two-component regulatory system</keyword>
    <feature type="domain" description="HAMP" evidence="13">
        <location>
            <begin position="29"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="domain" description="HAMP" evidence="13">
        <location>
            <begin position="121"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="domain" description="HAMP" evidence="13">
        <location>
            <begin position="213"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="domain" description="HAMP" evidence="13">
        <location>
            <begin position="305"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="11">
        <location>
            <begin position="379"/>
            <end position="600"/>
        </location>
    </feature>
    <feature type="domain" description="Response regulatory" evidence="12">
        <location>
            <begin position="752"/>
            <end position="872"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="10">
        <location>
            <position position="801"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="14">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="OBZ82508.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="890" mass="97466" checksum="5A528FDFB11136D8" modified="2016-11-30" version="1" fragment="single">EGKLGGQAVVQGVAGTWNELTDNVNIMAANLTNQVRSIAEVTKAVANGDLSKKIHVETRGEILDLKITVNDMVDQLREFSSEVTRVAREVGTDGALGGQANVQGVAGTWKDLTDNVNTMATNLTTQVRSIAVVTKAVAKGDLSKKIEVETRGEIRELKETVNDMVDQLRVFAAEVTRVAREVGTEGILGGQATIVGVDGTWKDLTDNVNLMASNLTDQLRAIAAVCKAVAQGDLSKKIEVEVHGEIAELKNTINTMVDQLSSFASEVTRVAKEVGTEGKLGVQAQVEDIEGLWRDITSNVNTMASNLTTQVRAFAQISAAATENDFSRLITVEASGEMDSLKTKINQMVGSLRDAIQKNRLAREAAELANRSKSEFLANMSHEIRTPMNGIIGMTTLTLETELTRQQRENLMIVSSLANSLLTIIDDILDISKIEAGRMTIESIPFSLRSAVFSVLKTLAVKANQKKLDLIYHVDQSIPDQLIGDPLRLRQVITNLIGNAVKFTTQGEVVLRTRSVRMQDGTVVLEFCVSDTGIGIQEDKLNVIFDTFCQADGSTTREYGGTGLGLSISRHLVQLMGGDLWVESKYGRGSEFYFTVSLLRYNLDDKEIKDKMHRFRNRRVLFLDSMNDQTGALNKISMLGLKPYRVGSIEEAAAVSIANSSKVKHAPFFDTVIIDKMAFAEKIREIVPLRYTPIVLIAPEAHLLNMKLCIDLGITGYANSPSNLADMFAVLLPALESHAALPSDASKTVPLEILLAEDNDVNQKLAVRILEKFGHHVKVVANGKLAVEAFESQEFDLILMDVQMPVMGGFEATQKIREIEHSMNNKSHIPIIALTAHAMIGDREKCLQAGMDEYVTKPLRFPELIAAIKKFAPQSAHMMEGKPKPSLLKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N0S1</accession>
    <name>A0A1C7N0S1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Pleckstrin y domain-containing family G member 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">PLEKHG2</name>
        <name evidence="3" type="ORF">A0J61_09214</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000799">
        <property type="protein sequence ID" value="OBZ82735.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N0S1"/>
    <dbReference type="FunCoup" id="A0A1C7N0S1">
        <property type="interactions" value="354"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N0S1"/>
    <dbReference type="InParanoid" id="A0A1C7N0S1"/>
    <dbReference type="OrthoDB" id="660555at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005085">
        <property type="term" value="F:guanyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035556">
        <property type="term" value="P:intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00160">
        <property type="entry name" value="RhoGEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.900.10">
        <property type="entry name" value="Dbl homology (DH) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035899">
        <property type="entry name" value="DBL_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000219">
        <property type="entry name" value="DH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051092">
        <property type="entry name" value="FYVE_RhoGEF_PH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001331">
        <property type="entry name" value="GDS_CDC24_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12673">
        <property type="entry name" value="FACIOGENITAL DYSPLASIA PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12673:SF159">
        <property type="entry name" value="LD03170P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00621">
        <property type="entry name" value="RhoGEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00325">
        <property type="entry name" value="RhoGEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48065">
        <property type="entry name" value="DBL homology domain (DH-domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00741">
        <property type="entry name" value="DH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50010">
        <property type="entry name" value="DH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DH" evidence="2">
        <location>
            <begin position="344"/>
            <end position="524"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="173"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="174"/>
            <end position="186"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ82735.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="539" mass="61237" checksum="0BED594CC1791BD0" modified="2016-11-30" version="1">MPIIDVHRSKKSTATTSLKPALFLRKIKKSSATVRNDEPSPTDTDITDKNSSISISSKIQSLMFAVRRKDSIAKQKKSSKYTTMKISSSTSLCVLPSACPNRSKCSNRPLSQFFFSTKSSLTEDSTEGEMISEDDLMIKDPAHVEKGFQQQQQTKQRQFKRLSLGLDFDRQQGRSHSCASSEKGTCSNSSSRSSSLKTIRNGYLDNRLLEEEENNICLQTNETGLQSDITFACSTTSSQSSTKEHYWSTPLYNKEKRLSSVARARTVLGFDSLRSRESRAIGVWRNTVSQLLSEPNSDTSTETIEENSHYQELYRIITHPALIKEDILEQQRFVRQSSPKNLAMIKFILNELSETERSYNQLLKLIQDRYMKPMIDASQAKYSLVKAADIPLLFSHLPELIELSDKLLDQFKSTSNVGLVFRSVEASLVVFLKYSMHYKSNMKLIRRACSNVLFMKINQENLSRKDTNRLGMSDYLIAPIQRIPRYCLLLKDLQKYTHPSESHRIDLDYVLKVLTGLAVAMDHVQSNNKAVALQPRISP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N0S5</accession>
    <name>A0A1C7N0S5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_10998</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001575">
        <property type="protein sequence ID" value="OBZ80954.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N0S5"/>
    <dbReference type="InParanoid" id="A0A1C7N0S5"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ80954.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="123" mass="14351" checksum="198E986AE62B6255" modified="2016-11-30" version="1">MVVLHLRYRRAKVALMNLVNAVCISLQKSITATDLDDMNRHTITKAYILEFERLTKQNRQQVESMPEKETGNILRRLNYFKELHSQQLHNTMLPSSLGAHDDFLDYLGDCIGDMPQLWSKFKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N138</accession>
    <name>A0A1C7N138_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_09242</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000806">
        <property type="protein sequence ID" value="OBZ82708.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N138"/>
    <dbReference type="STRING" id="101091.A0A1C7N138"/>
    <dbReference type="InParanoid" id="A0A1C7N138"/>
    <dbReference type="OrthoDB" id="270318at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ82708.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="351" mass="40762" checksum="D64E97C07224C0D6" modified="2016-11-30" version="1">MTLILSSKSLFKRLQLKKSNKKPDRISCLPRELLVCIYQQLQTPDCTRAFAATSRLFRQIALQPHSKAAWIVTRLGPRYALYYALLNLPDHCTGQFIQSLFHLGAQVPRCLLQALIQHYGKPVQDLHSDPRRRQDPFPRAIQRLSFDGYATIIQRAHLCYRPKLQSTEDLSLFLTALTDHDNKTVDTMVSQEWFLLTSFTARKTTPMSYPAFVQLLQSEHDRVLAPIFEFDPVARFCLWEACLMILFEEAFRSSELTAERKALLEHVSTFVSWPASFLDDRSLFCQAFSNFFTKYPKGYCQASTMNRLINLLYRYAQPACFHLPMALEHIIQAQMGREDTIQHIQQFLQTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N1R9</accession>
    <name>A0A1C7N1R9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glycogen debranching enzyme</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">GDB1_1</name>
        <name evidence="3" type="ORF">A0J61_08908</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000733">
        <property type="protein sequence ID" value="OBZ83042.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N1R9"/>
    <dbReference type="STRING" id="101091.A0A1C7N1R9"/>
    <dbReference type="InParanoid" id="A0A1C7N1R9"/>
    <dbReference type="OrthoDB" id="2415854at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004134">
        <property type="term" value="F:4-alpha-glucanotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004135">
        <property type="term" value="F:amylo-alpha-1,6-glucosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005980">
        <property type="term" value="P:glycogen catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11327">
        <property type="entry name" value="AmyAc_Glg_debranch_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010401">
        <property type="entry name" value="AGL/Gdb1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029436">
        <property type="entry name" value="AGL_euk_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032792">
        <property type="entry name" value="AGL_glucanoTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10569">
        <property type="entry name" value="GLYCOGEN DEBRANCHING ENZYME"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10569:SF2">
        <property type="entry name" value="GLYCOGEN DEBRANCHING ENZYME"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14701">
        <property type="entry name" value="hDGE_amylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14699">
        <property type="entry name" value="hGDE_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Eukaryotic glycogen debranching enzyme N-terminal" evidence="1">
        <location>
            <begin position="46"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="domain" description="Glycogen debranching enzyme glucanotransferase" evidence="2">
        <location>
            <begin position="144"/>
            <end position="585"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="616"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF14699"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF14701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ83042.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="616" mass="69883" checksum="21525768A96EDEFD" modified="2016-11-30" version="1" fragment="single">MVNAKEAKTTQDLPYLYALTLADNGSPTHDKNYIRIPLTKGDVLLRIILKAGSLAAGGKPILYTNYPVKGQFERHIFHPVKFIKDPNLLHAYCDVKLDLPGAYQYKVEYTEDDKKIVSETGYFIAEPRLKLPKAIGEHGKNDLLPLDGLMILSMVPKWMGPITKWKSLIQEVEYAGYNMIHFVPLQKRGSSNSPYSIADQLTYDDDVFEESDRKKSPNQKLAIVQSAIKEIHSKHGILSLSDVVWNHTSNSTAFLLDHPEAGYNLHNSPHLVPAYELDTALIELSGRFDQAGLPSDIRSSDDADKVIEYIKHNVFKDLKLYEFKVIDVDKHVEEIRNALQSRKLKCDPSAYQDVHGLSVKERVDLFGKSVVKDGHLGTRFHKSVDVSQAVSFLLAFNHISGLDQVSDDKVESLAQSFQGLLNDYNLPFYEEYDAECKIALDNIKGRLLFTRLAENGPKLGKITRENPVIETYFTRLEDKSNKHPKGSMMLANNGWIWNADPLNDFAGPGSTAYLRREVIIWGDCVKLRYGNAPQDNPWLWKHMRDYTEQIAGMFHGIRIDNCHSTPIHVAEYFLDAARKIRPDLYVLAELFTGSPERDNQFVSRLGIHALIREAMQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N1W2</accession>
    <name>A0A1C7N1W2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Pleckstrin y domain-containing family G member 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">PLEKHG1_1</name>
        <name evidence="3" type="ORF">A0J61_09333</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000826">
        <property type="protein sequence ID" value="OBZ82619.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N1W2"/>
    <dbReference type="STRING" id="101091.A0A1C7N1W2"/>
    <dbReference type="InParanoid" id="A0A1C7N1W2"/>
    <dbReference type="OrthoDB" id="1716625at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005085">
        <property type="term" value="F:guanyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.900.10">
        <property type="entry name" value="Dbl homology (DH) domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035899">
        <property type="entry name" value="DBL_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000219">
        <property type="entry name" value="DH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051092">
        <property type="entry name" value="FYVE_RhoGEF_PH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12673">
        <property type="entry name" value="FACIOGENITAL DYSPLASIA PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12673:SF270">
        <property type="entry name" value="FYVE-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00621">
        <property type="entry name" value="RhoGEF"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00325">
        <property type="entry name" value="RhoGEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48065">
        <property type="entry name" value="DBL homology domain (DH-domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50010">
        <property type="entry name" value="DH_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DH" evidence="2">
        <location>
            <begin position="40"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="domain" description="DH" evidence="2">
        <location>
            <begin position="120"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="604"/>
            <end position="625"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="675"/>
            <end position="696"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="604"/>
            <end position="616"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ82619.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="755" mass="86086" checksum="2434F03719AF7E48" modified="2016-11-30" version="1">MNSTALSESTKVLQSSRGTLLIDDKNIQQESNEPEKMQKKKLLAIEELLQTEHDYVQDLFYLVQVYLETLSRQPWISQEHKQIIVRNAPDIFKFHKQFIASFSAGSLTYDFNSSIVAKKFLDQPVQRICRYHLLIREIIRYTSPQTAEYDLWNVVLSEMQDVVSEINDFKLQRDMKERTELFIKRLDEDWRMSKQHLTQLGNLLIAGGIEVTYSALGQSVSKPRYLGCFVFNTYIIMVRPKKVISYEPKHWFPLHLTDFEDLPNIEVRCKKHTFAFSASCAQEKQAWIKKIQEAISYAKDNYNNSREGIMMPHDFIVSSLPGLSNKQSSSFQKLHLSRSFSSLLDMSGGSHKINEREAISNSPVGSYRALHADLKSNNSDTIVSDQTFLKSISNEEAMKKGQRANHPNHISRRSQSSLQLQLGAHSDLDVSTDYMDKPTTCRRPSSLELLSSNSNMIGKMSLQFKSNQQNAFRITVDHKLRDVCTQEYLSSRAWHVRDKDQTTGESMATESNLLKKRKSTSFIRTSASSFSLIKRATTDSTKLALQTADLEDPLTGSYPSSIDRSGSPINHLLDKIQLGSSMQGSSSSQLLRGMSFIRVDSPLSYDSESSINSNSSQKRVERKTSRRHVLVDKVLRRITSVHHKHLSSSSERSSFGFDGDHELKKAAFIDTKMKHEESSHLEINDRPSEETENAKKERQIVITGDQNNTSTCSFSAFAYASTPIPVEEEPIKKKKKWKTKLNRMRPASFLKLAAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-06-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N1Z7</accession>
    <name>A0A1C7N1Z7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_08820</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000716">
        <property type="protein sequence ID" value="OBZ83132.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N1Z7"/>
    <dbReference type="InParanoid" id="A0A1C7N1Z7"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ83132.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="153" mass="17888" checksum="C541DE7AD3EC5419" modified="2016-11-30" version="1">MQYVQSLNLASQSHLLQDISLINLIRSRTGLSIVYLMALNALLSRLCFILQNQAYSMPNFYFDSYIIHQTNSLITYCLISASHVCWPQLNSTTRRPLCRLPFQNRQDTLNCRRTSNKHKLLWLSLGYSMTCPIHPPHSLTEFHAIHFLNLHYY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N2B3</accession>
    <name>A0A1C7N2B3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Polyadenylation factor subunit 2</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="18">WD repeat-containing protein 33</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="19">WD repeat-containing protein of 146 kDa</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="17">pre-mRNA 3' end processing protein WDR33</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="22" type="primary">Wdr33</name>
        <name evidence="22" type="ORF">A0J61_08699</name>
    </gene>
    <organism evidence="22 23">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="22 23" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="22 23">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="14">Essential for both cleavage and polyadenylation of pre-mRNA 3' ends.</text>
    </comment>
    <comment type="function">
        <text evidence="12">Required for 3'-end cleavage and polyadenylation of pre-mRNAs. Also involved in chromosome segregation where it has a role in chromosome attachment to the mitotic spindle.</text>
    </comment>
    <comment type="subunit">
        <text evidence="16">Component of the cleavage and polyadenylation specificity factor (CPSF) module of the pre-mRNA 3'-end processing complex. Interacts with CPSF3/CPSF73.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="15">Belongs to the WD repeat WDR33 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="22">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000695">
        <property type="protein sequence ID" value="OBZ83252.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="FunCoup" id="A0A1C7N2B3">
        <property type="interactions" value="151"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N2B3"/>
    <dbReference type="InParanoid" id="A0A1C7N2B3"/>
    <dbReference type="OrthoDB" id="16717at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005847">
        <property type="term" value="C:mRNA cleavage and polyadenylation specificity factor complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031124">
        <property type="term" value="P:mRNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.10:FF:000069">
        <property type="entry name" value="WD repeat domain 33"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.10:FF:000077">
        <property type="entry name" value="WD repeat domain 33"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.10:FF:000085">
        <property type="entry name" value="WD repeat domain 33"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045245">
        <property type="entry name" value="Pfs2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22836:SF0">
        <property type="entry name" value="PRE-MRNA 3' END PROCESSING PROTEIN WDR33"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22836">
        <property type="entry name" value="WD40 REPEAT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="6"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0007">Acetylation</keyword>
    <keyword evidence="10" id="KW-0176">Collagen</keyword>
    <keyword evidence="3" id="KW-1017">Isopeptide bond</keyword>
    <keyword evidence="2" id="KW-0488">Methylation</keyword>
    <keyword evidence="6" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="11" id="KW-0539">Nucleus</keyword>
    <keyword evidence="4" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="23" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0677">Repeat</keyword>
    <keyword evidence="8" id="KW-0832">Ubl conjugation</keyword>
    <keyword evidence="5 20" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="20">
        <location>
            <begin position="126"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="20">
        <location>
            <begin position="161"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="20">
        <location>
            <begin position="202"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="20">
        <location>
            <begin position="244"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="20">
        <location>
            <begin position="286"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="20">
        <location>
            <begin position="328"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="20">
        <location>
            <begin position="372"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="21">
        <location>
            <begin position="1"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="21">
        <location>
            <begin position="404"/>
            <end position="679"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="21">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="21">
        <location>
            <begin position="412"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="21">
        <location>
            <begin position="537"/>
            <end position="549"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="21">
        <location>
            <begin position="565"/>
            <end position="584"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="21">
        <location>
            <begin position="585"/>
            <end position="595"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="21">
        <location>
            <begin position="601"/>
            <end position="616"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="21">
        <location>
            <begin position="646"/>
            <end position="665"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="21">
        <location>
            <begin position="670"/>
            <end position="679"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022499"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022843"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022990"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00025498"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00026154"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00058681"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00061690"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00063159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00068823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00075792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00076133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="21">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="EMBL" id="OBZ83252.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="679" mass="78383" checksum="C7406652184F6F60" modified="2016-11-30" version="1">MIDVSSHNNWDSENNNGGGSSNNRRPMRTSNREEGGGGNIPFSKMVFDGKRMRKAIQRRTVDYNHSVARWMQERVWIRDRRDTRYLRPDPNFIVDLLPPAAYLDNPINAVTTKFIHTSTNKIRFPVNVVRWTPEGRRLITGSSSGEFTLWNGLTFNFETILQAHDSAVRAMNWSHNDNWMVTGDHSGIIKYWQSNMSNLKIIQGHKEAIRDLTFAPSDTRFATCSDDSLIKIWDFNTGAEEKQLTGHGWDVKCIDWHPYKSLLASGSKDNLIKLWDPKTAKNITTLHGHKNTVLALQWNQNGNWLVTAGRDQLVKVYDIRTMKELQIFRGHKKEICSAKWHPQHERLLATGGSDGALMFWMTGQDRPIGEQETAHESNIWSLDWHPVGHILVSGSNDHTTRFWTRPRPGELTSDKFDSSQHHEEEAAVNTQNNGYAMKSFEDHARSQQFTEPPPFRPHNAPQPTKLEPPPFRPANGPLLSNSIPPPASSSSYQNASGPPPFRPTHYDIPGHSSFRPLPPLMMDNYMRQNQPHPPPTHMQQQNYNNNNNNRGSSIRPFGRGGGHMQQQHQQHQQQQQQQQPQQQQRSHHQQQHHYKPPPPMMNHNSSNNRYNHNDFNQQRMNNHNTKRPYQHNNDGPGYRPPPPFGSPGMMQPPXMILQQQQQQQQAYQRDPNKKMRRWD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N2G1</accession>
    <name>A0A1C7N2G1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">BZIP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_08644</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000686">
        <property type="protein sequence ID" value="OBZ83303.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N2G1"/>
    <dbReference type="STRING" id="101091.A0A1C7N2G1"/>
    <dbReference type="InParanoid" id="A0A1C7N2G1"/>
    <dbReference type="OrthoDB" id="2593073at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd14688">
        <property type="entry name" value="bZIP_YAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.170">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004827">
        <property type="entry name" value="bZIP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046347">
        <property type="entry name" value="bZIP_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021833">
        <property type="entry name" value="DUF3425"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38116:SF9">
        <property type="entry name" value="BZIP DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38116">
        <property type="entry name" value="CHROMOSOME 7, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00170">
        <property type="entry name" value="bZIP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11905">
        <property type="entry name" value="DUF3425"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00338">
        <property type="entry name" value="BRLZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57959">
        <property type="entry name" value="Leucine zipper domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50217">
        <property type="entry name" value="BZIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00036">
        <property type="entry name" value="BZIP_BASIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BZIP" evidence="2">
        <location>
            <begin position="70"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="19"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="197"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="498"/>
            <end position="540"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="39"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="80"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="219"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="252"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="295"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="305"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="514"/>
            <end position="526"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="566"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ83303.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="566" mass="63198" checksum="72080734D1362C90" modified="2016-11-30" version="1" fragment="single">MEGNVIGTSSYSEAMDLSDFDESGYDHTSVVSHDDHLVHSSQHANSSQDPPVKIRKKPGRKPNPASPALRKAQNRAAQRAFRERKERHMKELESSIKGIKEQRDKLLQENEKITNENEIIKAENWYLKGIVLSLQLVCLQHNLVIPQHGPHVNEQTLAVLAQSIPESISSYLNVNAKGKLHVSSRLLNETPDISNLSTLQQQKQQQEQQHRQDRQPSQSPNQFHNPLSQPLPVGSLIITQDGVHPVQDKRGSTTSSQSYNHYNTNSNNINSNLQQPSSWYHQANKPGQQPAFDFVSERLSRHESPSVSSQDESLNNMPPLSPMSASDRERAGINRASSPLSMFSSDLGRELPSQLPRPATLNEPVASNLAAIQALRLRLRLQSACVSMQSVPFAIQPTLLQLAVPHDPRIDLIPTPHMRDRMILYRDQFDLDDCFRCLLGGSVFHGGDPGVAGNWQLPAEFFEKFWFLTIDYNLRRCTNEWRKKQGLKELKTNITSLNEGAKPSQAPSSVPFNSASSTKSTTSTASIPSEPIYTNQSPVNPSMGIRPELSYDQLQGYLGVQIGSKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N2W4</accession>
    <name>A0A1C7N2W4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_08943</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000740">
        <property type="protein sequence ID" value="OBZ83006.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N2W4"/>
    <dbReference type="InParanoid" id="A0A1C7N2W4"/>
    <dbReference type="OrthoDB" id="2287781at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="144"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="146"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="232"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="251"/>
            <end position="275"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ83006.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="285" mass="33372" checksum="2C40FA8D20FD6D86" modified="2016-11-30" version="1">MVETKKISQEDSSEYTVIYIENPDTENITYKAIGTYKDQEEAYAAAIVNQLQVIEHVSKSWPKAILINKQDHILELCQKLKQDFTTYQERFIFLTAQCSHLFQDLLHGQHHVLISNRANKPQIINESIFKTKLRNFLDAFQTRTDIEEDLDNSDEDDDEDEEDDSDGEEEDLGEEEESEDGEELEEDIPEEEEEEGHNEDSMEEDLIEEEEEEEEEEEEEEERSNTNVVPETTEDELDEEEGSGLKREASTLDEEDDEEDEIEEDNDEDELEEEDNSNKRRRTTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N306</accession>
    <name>A0A1C7N306_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_08444</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000651">
        <property type="protein sequence ID" value="OBZ83503.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N306"/>
    <dbReference type="InParanoid" id="A0A1C7N306"/>
    <dbReference type="OrthoDB" id="2417678at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ83503.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="78" mass="8815" checksum="CF19C7B975E351FB" modified="2016-11-30" version="1">MSMPNYADKVMSRFGHHLSPQQRTMFSDAMIPNFHSSSHQQYQANHSLASVIVARDQQQRPGVTINSCLLHADKTDCN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N351</accession>
    <name>A0A1C7N351_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">40S ribosomal protein S14</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">rps14</name>
        <name evidence="6" type="ORF">A0J61_08446</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the universal ribosomal protein uS11 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000651">
        <property type="protein sequence ID" value="OBZ83501.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N351"/>
    <dbReference type="FunCoup" id="A0A1C7N351">
        <property type="interactions" value="434"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N351"/>
    <dbReference type="InParanoid" id="A0A1C7N351"/>
    <dbReference type="OrthoDB" id="1677536at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.80:FF:000002">
        <property type="entry name" value="40S ribosomal protein S14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.80">
        <property type="entry name" value="Ribosomal protein S11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01310">
        <property type="entry name" value="Ribosomal_uS11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001971">
        <property type="entry name" value="Ribosomal_uS11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018102">
        <property type="entry name" value="Ribosomal_uS11_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036967">
        <property type="entry name" value="Ribosomal_uS11_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF007176">
        <property type="entry name" value="PRK09607.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11759">
        <property type="entry name" value="40S RIBOSOMAL PROTEIN S14/30S RIBOSOMAL PROTEIN S11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00411">
        <property type="entry name" value="Ribosomal_S11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002131">
        <property type="entry name" value="Ribosomal_S11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53137">
        <property type="entry name" value="Translational machinery components"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00054">
        <property type="entry name" value="RIBOSOMAL_S11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 6" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="130"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="141"/>
            <end position="150"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003629"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OBZ83501.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="150" mass="15947" checksum="C7C867064C6E2FEE" modified="2016-11-30" version="1">MSKKTAAPKVVEKVQLGPQVREGELVFGVAHIFASFNDTFVHVTDLSGRETISRITGGMQVKADRDESSPYAAMLAAQQVAAKCKELGINALHVKLRATGGTGTKTPGPGGQAALRALARAGMRIGRIEDVTPIPTDSTRRKGGRRGRRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N353</accession>
    <name>A0A1C7N353_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">SEC7 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_08415</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000645">
        <property type="protein sequence ID" value="OBZ83532.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N353"/>
    <dbReference type="STRING" id="101091.A0A1C7N353"/>
    <dbReference type="InParanoid" id="A0A1C7N353"/>
    <dbReference type="OrthoDB" id="2157641at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005085">
        <property type="term" value="F:guanyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032012">
        <property type="term" value="P:regulation of ARF protein signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1000.11">
        <property type="entry name" value="Arf Nucleotide-binding Site Opener,domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023394">
        <property type="entry name" value="Sec7_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000904">
        <property type="entry name" value="Sec7_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035999">
        <property type="entry name" value="Sec7_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10663">
        <property type="entry name" value="GUANYL-NUCLEOTIDE EXCHANGE FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01369">
        <property type="entry name" value="Sec7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00222">
        <property type="entry name" value="Sec7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48425">
        <property type="entry name" value="Sec7 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50190">
        <property type="entry name" value="SEC7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SEC7" evidence="2">
        <location>
            <begin position="164"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="15"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="58"/>
            <end position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ83532.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="309" mass="35630" checksum="DC2BDEC14BC3F2DD" modified="2016-11-30" version="1">MALNLPKRSHSLAYRNQISESNRHGRSSSLTDTTKSRSDQIVRGKNQSMPSAPIVYQESDSNLSSKSIIPPTRSSSLTQSSTDEEVRQSLLDWKHKSVFRIDNLFSPVSLWNKQELIFGTVESLLLTEYQQQAENKASSLWEEQCNPREEIASDPFCHKVLVCYLRRFDFAGLTEAQEIDRILEAFSLQYWNTHQDDLLYKCADVVYTVTYSIMLLNTDLHLVQISHHRKMSCQTFCSNTLATLLEQDIPFEKNDILNTIWKYDMIERLKTIYVSVQNQGILHPSSGNQAKSFLKKVGSIRKRKKEVEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N4B3</accession>
    <name>A0A1C7N4B3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Leucine-rich repeat-containing protein 40</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">lrrc40</name>
        <name evidence="4" type="ORF">A0J61_08090</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000593">
        <property type="protein sequence ID" value="OBZ83857.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N4B3"/>
    <dbReference type="STRING" id="101091.A0A1C7N4B3"/>
    <dbReference type="InParanoid" id="A0A1C7N4B3"/>
    <dbReference type="OrthoDB" id="660555at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003591">
        <property type="entry name" value="Leu-rich_rpt_typical-subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050216">
        <property type="entry name" value="LRR_domain-containing"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48051">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48051:SF1">
        <property type="entry name" value="RAS SUPPRESSOR PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00560">
        <property type="entry name" value="LRR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13855">
        <property type="entry name" value="LRR_8"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00364">
        <property type="entry name" value="LRR_BAC"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SMART" id="SM00369">
        <property type="entry name" value="LRR_TYP"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="408"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="417"/>
            <end position="429"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OBZ83857.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="657" mass="73386" checksum="7CFDCF471FC5375F" modified="2016-11-30" version="1">MPTHLSNLLEGKTLTGVLPPEKQPPVQNLLPQYNQPALLDIESCVDSPFLGLHLKEPNRRRKSVKHHSGQVHIKRKQKIVTTTNTNSQHTDNTGGGHGLVMLRRRDLEADQLGEELDHLFLPTSNSYLKPTFSLSQYSSLVELDISRNQLSRLPSQICHLTQLRVLNMTSNQLIEIPFELYALHALEVLVLSQNQIQVIPEDMPERLPNLITLRLAANKINQLPEKLEHWQRMRHLQLGSVFGGNQLVRLPDSITQMSALEELDISYNQLKSLPHDLVIDSLQILNVSHNQLDFIPKSITQCRQLKSLNVSKNHLTTLPADLVQLNRLELLDISENLLCIMPAEILEQMQSTNLLITGNPLTRPGHCDLSNQDPYSRILRQMTQYGVARSPASSPKVARISLREQCGPKGMGCLTPSSDQSSASSSSSFSDSQFITQSTLSTSNPSYFPPVTLPSFSSLPPLSPPPSSSLSLPPPMIVEESKAESVNSFTSVPHPQQDEDATIDHELSYHAQQLNIDGSRPVHDTNDLIGTSRSRIVQDSTQSKCILIDFPRESPLPTETGLLLSLREIASRTILKHKIDIPLIYLPRHLLQDLKAGRTCANCQDPFVNEWVTSVQVKSFGGHPAVVRRVRFCSTQCWTQCLPTKAHSKSVICVHQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N4M5</accession>
    <name>A0A1C7N4M5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">ATP-dependent DNA helicase pif1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">pif1_8</name>
        <name evidence="3" type="ORF">A0J61_09686</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000909">
        <property type="protein sequence ID" value="OBZ82264.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N4M5"/>
    <dbReference type="STRING" id="101091.A0A1C7N4M5"/>
    <dbReference type="InParanoid" id="A0A1C7N4M5"/>
    <dbReference type="OrthoDB" id="2281104at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd18809">
        <property type="entry name" value="SF1_C_RecD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025476">
        <property type="entry name" value="Helitron_helicase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049163">
        <property type="entry name" value="Pif1-like_2B_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051055">
        <property type="entry name" value="PIF1_helicase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47642">
        <property type="entry name" value="ATP-DEPENDENT DNA HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14214">
        <property type="entry name" value="Helitron_like_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21530">
        <property type="entry name" value="Pif1_2B_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0347">Helicase</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helitron helicase-like" evidence="1">
        <location>
            <begin position="35"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="domain" description="DNA helicase Pif1-like 2B" evidence="2">
        <location>
            <begin position="294"/>
            <end position="325"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF14214"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF21530"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ82264.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="426" mass="48975" checksum="5FD97FAE47529BD4" modified="2016-11-30" version="1">MTKNNIAAANRLVISTKGRSNIRQRDVIDAATKTYNKNIVSNVPYTVRLSYAYKRKNFLDLQTVFNNLGAPQLFFTFSCNDYSPDFTAATGTQYPWEDPVLFANHFNRKWNHFFNTYVLGHFAKMIGDVKDFSWVLEIQDRGSPHIHCVLWTEKSLQELVRFNVITCKLLPRRAADDPLLHDLILKHQTHICNPVYCKLGENRTCCFGYPKQAAPRTEFVGGSCIYERRVEDMNINNYNSYLLAVWRANMDIQYNCNDFDSMSEEPEFFLAHDTYNAGSKNSATRALNESRLLQELKLKTDMPVMLIQNLHVSSGWVNGTIAQVKEIDEETVLLSKEGPDGDELTLWIQKISRSVPETSYLRSQFSIVPAFASTIHKAQRTTIDSVAIYLDDMIAHGQLYVAMSRIRKSENLYFFGAELPLRIKRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N4Q8</accession>
    <name>A0A1C7N4Q8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">BZIP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">A0J61_07866</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000557">
        <property type="protein sequence ID" value="OBZ84093.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N4Q8"/>
    <dbReference type="STRING" id="101091.A0A1C7N4Q8"/>
    <dbReference type="InParanoid" id="A0A1C7N4Q8"/>
    <dbReference type="OrthoDB" id="5380163at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090575">
        <property type="term" value="C:RNA polymerase II transcription regulator complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001228">
        <property type="term" value="F:DNA-binding transcription activator activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000976">
        <property type="term" value="F:transcription cis-regulatory region binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033554">
        <property type="term" value="P:cellular response to stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd14688">
        <property type="entry name" value="bZIP_YAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.170">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.100">
        <property type="entry name" value="YAP1 redox domain. Chain B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050936">
        <property type="entry name" value="AP-1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004827">
        <property type="entry name" value="bZIP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046347">
        <property type="entry name" value="bZIP_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013910">
        <property type="entry name" value="TF_PAP1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023167">
        <property type="entry name" value="Yap1_redox_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40621:SF6">
        <property type="entry name" value="AP-1-LIKE TRANSCRIPTION FACTOR YAP1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40621">
        <property type="entry name" value="TRANSCRIPTION FACTOR KAPC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00170">
        <property type="entry name" value="bZIP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08601">
        <property type="entry name" value="PAP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00338">
        <property type="entry name" value="BRLZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57959">
        <property type="entry name" value="Leucine zipper domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111430">
        <property type="entry name" value="YAP1 redox domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00036">
        <property type="entry name" value="BZIP_BASIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BZIP" evidence="5">
        <location>
            <begin position="100"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="52"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="197"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="197"/>
            <end position="212"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS00036"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OBZ84093.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="332" mass="37812" checksum="8F0444E5508CC621" modified="2016-11-30" version="1">MNTTTLADIVQKIASQGNNPDVSFLKDDPEAQTMLLLALLSNNNVNTTTVEKRKYDASDDPISPPPPVESPTKSIDNKPKKVGRKPLTSEEEDSDNPKSKRKAQNRAAQRAFRERKENHVRVLEERVRELEQKISQQSNTDLAAENEKLKATIRQLEDENHRLLGATTSFDLPLVSEDGTRPQKLIRSSNHQSPISYFDSFSSTSSSNKSRSNTPEETLSLDDILQLPSNTLIDHSELLGLADDSLDLNNFFDQQKFTTDPSQFDFFYPVVEEPNKKKKKDVTQVWDDIANHPRFDEFDMDDLCDKMTKKATCSDYNHDKELKNLIDEHYPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N4R3</accession>
    <name>A0A1C7N4R3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_09647</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000899">
        <property type="protein sequence ID" value="OBZ82304.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N4R3"/>
    <dbReference type="STRING" id="101091.A0A1C7N4R3"/>
    <dbReference type="InParanoid" id="A0A1C7N4R3"/>
    <dbReference type="OrthoDB" id="2292563at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="22"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="28"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="40"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="116"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ82304.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="116" mass="13227" checksum="2CD740FEE5B89395" modified="2016-11-30" version="1" fragment="single">MVILLTFDMGVFAIIKTVFQSKENRRASSNSTSKDSSISVGNYTTNTQISSRSTGSYADQILTAKQINSEAGGYNYQYKDGRRYHAQKDVSYLLPNDDDEVDRVHQQHWILRHAFQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N4S7</accession>
    <name>A0A1C7N4S7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Protein pacG</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">pacG</name>
        <name evidence="5" type="ORF">A0J61_09626</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000894">
        <property type="protein sequence ID" value="OBZ82324.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N4S7"/>
    <dbReference type="InParanoid" id="A0A1C7N4S7"/>
    <dbReference type="OrthoDB" id="2288358at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000228">
        <property type="term" value="C:nuclear chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051321">
        <property type="term" value="P:meiotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1390">
        <property type="entry name" value="NDT80 DNA-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052605">
        <property type="entry name" value="Fungal_trans_regulator"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024061">
        <property type="entry name" value="NDT80_DNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037141">
        <property type="entry name" value="NDT80_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008967">
        <property type="entry name" value="p53-like_TF_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35144">
        <property type="entry name" value="MEIOSIS-SPECIFIC TRANSCRIPTION FACTOR NDT80"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35144:SF2">
        <property type="entry name" value="MEIOSIS-SPECIFIC TRANSCRIPTION FACTOR NDT80"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05224">
        <property type="entry name" value="NDT80_PhoG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49417">
        <property type="entry name" value="p53-like transcription factors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51517">
        <property type="entry name" value="NDT80"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NDT80" evidence="4">
        <location>
            <begin position="12"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="NDT80" evidence="2">
        <location>
            <begin position="12"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="253"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="459"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="515"/>
            <end position="542"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="20"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="319"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="340"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="362"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="373"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="459"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="520"/>
            <end position="531"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OBZ82324.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="542" mass="60669" checksum="255766A07705357E" modified="2016-11-30" version="1" fragment="single">SADSSAQITTNEGFPPPISKSVSTHFHAPSNNNHESHNVPETNFFCQSKPIYHLYDYNNKNSYPAILNCKMDRGFFVSQSHWTCYRRNYFQVTASVIIPDHTDQSSYALQVNPDKPXQPIQEFSVQLKAYTTTTTTTNNNTVHSLPSPSDTQTPFESHHAVKPITLTQMTAKRDKGPQNEPPILTIIPSDSAFNCEQLCVTFERLQFRVATANNGKRRASQQYFRLAFQLLAQLEDGSRHVISECCSSPLVVRGRSPGHYSSEPQRDLKRKKKMSPPVLSAPRQPSPSSVVINKAKDMLPSPTHSAGHPHMPVRTLSDGVPSSGTEGSSPSPHYSHSATLPPPPPPPPQYIYTPPSIVMDTRQPNTTDTSLSSPPPPPPPQHQQPLIPASIVNSAFSHLHARSQSANDSDFFARQRQNMKYPSVHQESGLFEYNVGIQNALRNWQQQVVRQRTDSATTFDSSYMSSSTTSHQEQVRSGTRPGTPLPYQNHAMFQHSPNPMANHWSPRQSHFMEDSKMNHHPQQNGYVNSQEESTKLYHSPTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N5P3</accession>
    <name>A0A1C7N5P3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">NADH-cytochrome b5 reductase</fullName>
            <ecNumber evidence="11">1.6.2.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">MCR1</name>
        <name evidence="13" type="ORF">A0J61_07495</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9 11">
            <text>2 Fe(III)-[cytochrome b5] + NADH = 2 Fe(II)-[cytochrome b5] + NAD(+) + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46680"/>
            <dbReference type="Rhea" id="RHEA-COMP:10438"/>
            <dbReference type="Rhea" id="RHEA-COMP:10439"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
            <dbReference type="ChEBI" id="CHEBI:29034"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.6.2.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 10 11">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion outer membrane</location>
            <topology evidence="2">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 11">Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.6.2.2" evidence="11"/>
    <dbReference type="EMBL" id="LUGH01000508">
        <property type="protein sequence ID" value="OBZ84453.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N5P3"/>
    <dbReference type="STRING" id="101091.A0A1C7N5P3"/>
    <dbReference type="InParanoid" id="A0A1C7N5P3"/>
    <dbReference type="OrthoDB" id="432685at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005741">
        <property type="term" value="C:mitochondrial outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090524">
        <property type="term" value="F:cytochrome-b5 reductase activity, acting on NADH"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd06183">
        <property type="entry name" value="cyt_b5_reduct_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.80:FF:000009">
        <property type="entry name" value="NADH-cytochrome b5 reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.80">
        <property type="entry name" value="Nucleotide-binding domain of ferredoxin-NADP reductase (FNR) module"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.10">
        <property type="entry name" value="Translation factors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001834">
        <property type="entry name" value="CBR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008333">
        <property type="entry name" value="Cbr1-like_FAD-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017927">
        <property type="entry name" value="FAD-bd_FR_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001709">
        <property type="entry name" value="Flavoprot_Pyr_Nucl_cyt_Rdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039261">
        <property type="entry name" value="FNR_nucleotide-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001433">
        <property type="entry name" value="OxRdtase_FAD/NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017938">
        <property type="entry name" value="Riboflavin_synthase-like_b-brl"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19370">
        <property type="entry name" value="NADH-CYTOCHROME B5 REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19370:SF171">
        <property type="entry name" value="NADH-CYTOCHROME B5 REDUCTASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00970">
        <property type="entry name" value="FAD_binding_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00175">
        <property type="entry name" value="NAD_binding_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00406">
        <property type="entry name" value="CYTB5RDTASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00371">
        <property type="entry name" value="FPNCR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52343">
        <property type="entry name" value="Ferredoxin reductase-like, C-terminal NADP-linked domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63380">
        <property type="entry name" value="Riboflavin synthase domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51384">
        <property type="entry name" value="FAD_FR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 10 11" id="KW-0274">FAD</keyword>
    <keyword evidence="4 10 11" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="8" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="7 11" id="KW-0520">NAD</keyword>
    <keyword evidence="6 11" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding FR-type" evidence="12">
        <location>
            <begin position="59"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="108"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="109"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="110"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="126"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="128"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="135"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="136"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004572"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006105"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00047682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR601834-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU361226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="OBZ84453.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="308" mass="35545" checksum="63D075E88F21C348" modified="2016-11-30" version="1">MFAHRSILTSSRRLFSTATHTKKSKKLQTLLLGTACLTASYFGWEKYDAYTNNNKLSQDQYTPLGLIKKQQISPDSYLLRLEVKKEQNKEYPVPSCVYIKDDAIQVMRPYTPINQNPYLDGYMDLVIKKYQDGSVSRTLTSFTPHQHKVHIRGPMVEPECLYEPKSVDEVGMIAGGTGISPMYQLICRILENPDDQTTSVWLIYGNKTEKDILLRQELDQLQAKYNDRFRVKYVLEDPPSDAYERGYVTENMIRDMMLNKEKRKIYVCGPNRMLAAVCGERARDYSQGPVTGLLSELGFQSDEIWKFQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N5R1</accession>
    <name>A0A1C7N5R1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="20">Phospholipid-transporting ATPase</fullName>
            <ecNumber evidence="20">7.6.2.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="25" type="ORF">A0J61_07971</name>
    </gene>
    <organism evidence="25 26">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="25 26" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="25 26">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="14 20">
            <text>ATP + H2O + phospholipidSide 1 = ADP + phosphate + phospholipidSide 2.</text>
            <dbReference type="EC" id="7.6.2.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="16">
            <text>a 1,2-diacyl-sn-glycero-3-phospho-L-serine(out) + ATP + H2O = a 1,2-diacyl-sn-glycero-3-phospho-L-serine(in) + ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:38567"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57262"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="16">
            <dbReference type="Rhea" id="RHEA:38568"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="15">
            <text>a 1,2-diacyl-sn-glycero-3-phosphoethanolamine(out) + ATP + H2O = a 1,2-diacyl-sn-glycero-3-phosphoethanolamine(in) + ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:66132"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:64612"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="15">
            <dbReference type="Rhea" id="RHEA:66133"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 19">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Golgi apparatus</location>
            <location evidence="2">trans-Golgi network membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="20">Membrane</location>
            <topology evidence="20">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 20">Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="25">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="7.6.2.1" evidence="20"/>
    <dbReference type="EMBL" id="LUGH01000574">
        <property type="protein sequence ID" value="OBZ83979.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N5R1"/>
    <dbReference type="FunCoup" id="A0A1C7N5R1">
        <property type="interactions" value="192"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N5R1"/>
    <dbReference type="InParanoid" id="A0A1C7N5R1"/>
    <dbReference type="OrthoDB" id="377733at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005802">
        <property type="term" value="C:trans-Golgi network"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090556">
        <property type="term" value="F:phosphatidylserine floppase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032456">
        <property type="term" value="P:endocytic recycling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045332">
        <property type="term" value="P:phospholipid translocation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006892">
        <property type="term" value="P:post-Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02073">
        <property type="entry name" value="P-type_ATPase_APLT_Dnf-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.70.150.10:FF:000026">
        <property type="entry name" value="Phospholipid-transporting ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.1110.10:FF:000087">
        <property type="entry name" value="Phospholipid-transporting ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1000:FF:000010">
        <property type="entry name" value="Phospholipid-transporting ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.150.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023299">
        <property type="entry name" value="ATPase_P-typ_cyto_dom_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018303">
        <property type="entry name" value="ATPase_P-typ_P_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023298">
        <property type="entry name" value="ATPase_P-typ_TM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008250">
        <property type="entry name" value="ATPase_P-typ_transduc_dom_A_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059000">
        <property type="entry name" value="ATPase_P-type_domA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006539">
        <property type="entry name" value="P-type_ATPase_IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032631">
        <property type="entry name" value="P-type_ATPase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001757">
        <property type="entry name" value="P_typ_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032630">
        <property type="entry name" value="P_typ_ATPase_c"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044492">
        <property type="entry name" value="P_typ_ATPase_HD_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01652">
        <property type="entry name" value="ATPase-Plipid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01494">
        <property type="entry name" value="ATPase_P-type"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24092:SF150">
        <property type="entry name" value="PHOSPHOLIPID-TRANSPORTING ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24092">
        <property type="entry name" value="PROBABLE PHOSPHOLIPID-TRANSPORTING ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13246">
        <property type="entry name" value="Cation_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00122">
        <property type="entry name" value="E1-E2_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16212">
        <property type="entry name" value="PhoLip_ATPase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16209">
        <property type="entry name" value="PhoLip_ATPase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00119">
        <property type="entry name" value="CATATPASE"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG00002">
        <property type="entry name" value="C1.7:_P-type_atpase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00003">
        <property type="entry name" value="Haloacid_Dehalogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00027">
        <property type="entry name" value="p-type_atpase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81653">
        <property type="entry name" value="Calcium ATPase, transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81665">
        <property type="entry name" value="Calcium ATPase, transmembrane domain M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81660">
        <property type="entry name" value="Metal cation-transporting ATPase, ATP-binding domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00154">
        <property type="entry name" value="ATPASE_E1_E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 18 20" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="12" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="9 19 20" id="KW-0460">Magnesium</keyword>
    <keyword evidence="13 20" id="KW-0472">Membrane</keyword>
    <keyword evidence="6 19" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 18 20" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="26" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10 20" id="KW-1278">Translocase</keyword>
    <keyword evidence="5 20" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="11 20" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="20">
        <location>
            <begin position="410"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="20">
        <location>
            <begin position="453"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="20">
        <location>
            <begin position="971"/>
            <end position="990"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="20">
        <location>
            <begin position="1010"/>
            <end position="1032"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="20">
        <location>
            <begin position="1053"/>
            <end position="1076"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="20">
        <location>
            <begin position="1088"/>
            <end position="1106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="20">
        <location>
            <begin position="1118"/>
            <end position="1140"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="20">
        <location>
            <begin position="1160"/>
            <end position="1178"/>
        </location>
    </feature>
    <feature type="domain" description="P-type ATPase N-terminal" evidence="23">
        <location>
            <begin position="145"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="domain" description="P-type ATPase A" evidence="22">
        <location>
            <begin position="239"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="domain" description="P-type ATPase C-terminal" evidence="24">
        <location>
            <begin position="939"/>
            <end position="1192"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="21">
        <location>
            <begin position="1"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="21">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="21">
        <location>
            <begin position="34"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="21">
        <location>
            <begin position="60"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="active site" description="4-aspartylphosphate intermediate" evidence="17">
        <location>
            <position position="522"/>
        </location>
    </feature>
    <feature type="binding site" evidence="18">
        <location>
            <position position="522"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="19">
        <location>
            <position position="522"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="18">
        <location>
            <position position="523"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="18">
        <location>
            <position position="524"/>
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        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
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        <location>
            <position position="524"/>
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        <ligand>
            <name>Mg(2+)</name>
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        <location>
            <position position="617"/>
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        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
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        <location>
            <position position="658"/>
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        <ligand>
            <name>ATP</name>
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        </ligand>
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    <feature type="binding site" evidence="18">
        <location>
            <position position="681"/>
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        <ligand>
            <name>ATP</name>
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        </ligand>
    </feature>
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        <location>
            <position position="714"/>
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        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="18">
        <location>
            <position position="794"/>
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        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="18">
        <location>
            <position position="795"/>
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        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="18">
        <location>
            <position position="796"/>
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        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="18">
        <location>
            <position position="887"/>
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        <ligand>
            <name>ATP</name>
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        <location>
            <position position="893"/>
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        <ligand>
            <name>ATP</name>
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        <location>
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            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
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        <location>
            <position position="916"/>
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            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
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        <location>
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        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
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            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
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    <feature type="non-terminal residue" evidence="25">
        <location>
            <position position="1"/>
        </location>
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    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
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    </evidence>
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            <dbReference type="ARBA" id="ARBA00004166"/>
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    </evidence>
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            <dbReference type="ARBA" id="ARBA00008109"/>
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    </evidence>
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            <dbReference type="ARBA" id="ARBA00022553"/>
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    </evidence>
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            <dbReference type="ARBA" id="ARBA00022692"/>
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        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
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    </evidence>
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            <dbReference type="ARBA" id="ARBA00051303"/>
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        <source>
            <dbReference type="PIRSR" id="PIRSR606539-1"/>
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        <source>
            <dbReference type="PIRSR" id="PIRSR606539-2"/>
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        <source>
            <dbReference type="RuleBase" id="RU362033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="21">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="22">
        <source>
            <dbReference type="Pfam" id="PF00122"/>
        </source>
    </evidence>
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            <dbReference type="Pfam" id="PF16209"/>
        </source>
    </evidence>
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            <dbReference type="Pfam" id="PF16212"/>
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    </evidence>
    <evidence type="ECO:0000313" key="25">
        <source>
            <dbReference type="EMBL" id="OBZ83979.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="26">
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            <dbReference type="Proteomes" id="UP000093000"/>
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    </evidence>
    <sequence length="1260" mass="143057" checksum="35148B4E87C3ED02" modified="2016-11-30" version="1" fragment="single">DSTEENPFTDQQGYSPSIARNDLIDLQQGPPSPAQTTFPFSSSSQPPLKDPSLAHRRQSRQRDALLDDPKLEDHEDHSNTYNERSIILSEGESTSPYARANMQLPTKKKKIHRPWRQVLKDTYHHLIGNTGKASGIPTENGARIIHINNKLLNDEQKFLHNGITTGKYSIISFLPKFLYEEFSKYANLFFLFVSCIQQIPDVSPTSRWTTLVPLVIVLLITAIKEMVEDWGVHRSDRELNSKSCKVLEGTQFVEKQWKDIKVGDVLRIESGENFPADLVLISSSEPEGLCYIETSNLDGEVNLKIKQALPQTAKILNPTDMSQLQGVIQSEQPNNRLYNYDGTLSLTDAGHPRDIPIDPTQLLLRGAQLRNTSWIYGIAIFTGHETKLMLNSSKKPSKISNVTRITNRNIMYLFWILVGMSLAGAIGGVLFSMYKGSSATYLPLRSLSYGQEFGYDILTFLILFNSFIPISLMVTMEVVKFVLSYLIECDLDIYYELTDTPATARSSSLIEELGQVKFIFSDKTGTLTCNEMQFRQASIGGLFYVDQVDPDKKAQGESNDPTLQYSFDQLLQEHLQTHSTANVINEFLTLLAVCHTVIPERQEGSEDIVYQASSPDEGALVKGAANLGYRFHTRRPNSITCSIRGQDQEFQVLNICEFNSTRKRMSAIIRGPDGRIKLYCKGADTVILERLAAENPFVEPTLVQLEECASEGLRTLCIAMREIPEEEYQRWSQIQEAASTTLVNRAEELDKAAELIEKDLFLLGATAIEDRLQDGVPDTIHTLQEAGIKVWVLTGDRQETAINIGYSCRLLNEDMSLIVCNEDNHWETKSFLEKKLRDINEVKLRGEELEPLALIIDGKALTFALEKDIEKVFFDLAVLCKAVVCCRVSPLQKALVVKCVKKFDTSILLAIGDGANDVSMIQAAHVGIGISGVEGLQAARSADFAISQFRFLKKLLLVHGAWAYQRLSKMIFYYFYKNVALYLTQFWYAFYNGFSGSTLYESWTMSCFNVIFTFLPPLAIGIFDQIVSSRMLDKYPQMYMLGQNNVFFNQKKFWGWMTNATYHSLVLFFLGVGAFRTEGVFKNGMTSGQWWAGAAVFTGVLGAILWKGALIIDYWTKYTAIAMIASMAVWFLYVIIVSYIPPAISIDALPEYYDMVPMLWGNVNFWLFLLIVPFICNLRDFIWKYAQRVIWPMPYHFVQEIQKHNLPDYRPRMDRFRQAVNKVRRIQRLKRNRGYAFSQNETDQTKIIRAYDTTVQKPSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N669</accession>
    <name>A0A1C7N669_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Phylloquinone omega-hydroxylase CYP4F2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">CYP4F2</name>
        <name evidence="9" type="ORF">A0J61_07308</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1 8">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000486">
        <property type="protein sequence ID" value="OBZ84645.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N669"/>
    <dbReference type="STRING" id="101091.A0A1C7N669"/>
    <dbReference type="InParanoid" id="A0A1C7N669"/>
    <dbReference type="OrthoDB" id="1470350at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050196">
        <property type="entry name" value="Cytochrome_P450_Monoox"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24291:SF50">
        <property type="entry name" value="BIFUNCTIONAL ALBAFLAVENONE MONOOXYGENASE_TERPENE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24291">
        <property type="entry name" value="CYTOCHROME P450 FAMILY 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 7 8" id="KW-0349">Heme</keyword>
    <keyword evidence="5 7 8" id="KW-0408">Iron</keyword>
    <keyword evidence="3 7 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 8" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="4 8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" description="axial binding residue" evidence="7">
        <location>
            <position position="469"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OBZ84645.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="525" mass="60313" checksum="616BF3BE431B52FD" modified="2016-11-30" version="1">MFTETALQIYHQMAEKVLPILKRQPKSSYIGAALVFLLVAEIRRQLSVPKHLKKFPTIGVFTLMKSFMRNDSVIERHNRLVAPIVKQGHKFYAAKIPFDWSLSIVDPEIAKIMLMKSDAFPKSQGFTRKLGDSSLIVRFTGRDNVSISNGHVWKRQRKFMNPAFRRSTPIKTFGELTLKFFDCVDEQPQDFPAAIKLKNYTLDALGIAAFDFDFKSLSGDPEGWTEIYNVIMKGMFDPWVFLFGKMEFILQYIIPSKRECIKSVVKFNKMLVEMADKRRQEIQNGKKLNTPNSEKDLLTLMIEAEMEEGIMTTNEELRENIALFFLAGQDSTGNSLSFCLYHLAKNKHVQDKLRREIMSVMGDRDLDAIPTVEDFKDMPYLNMVIKENLRLSGPADRFLDRVVAEDIVLGGELIPKGTLITVDVASIHYNPEYWHDPEVFIPERFEPNGEFDQHAGVAWLPFSNGARQCIGMNFSLAEQRVFLTMLLRRYEVGISKDSIHYDSIVYEQSFTFAPSSLTLNFTKLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N6A9</accession>
    <name>A0A1C7N6A9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">TBC1 domain family member 20</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">Tbc1d20_1</name>
        <name evidence="3" type="ORF">A0J61_07285</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000484">
        <property type="protein sequence ID" value="OBZ84662.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N6A9"/>
    <dbReference type="FunCoup" id="A0A1C7N6A9">
        <property type="interactions" value="320"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N6A9"/>
    <dbReference type="InParanoid" id="A0A1C7N6A9"/>
    <dbReference type="OrthoDB" id="206700at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006888">
        <property type="term" value="P:endoplasmic reticulum to Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.1310">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.80">
        <property type="entry name" value="Ypt/Rab-GAP domain of gyp1p, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000195">
        <property type="entry name" value="Rab-GAP-TBC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035969">
        <property type="entry name" value="Rab-GAP_TBC_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045913">
        <property type="entry name" value="TBC20/Gyp8-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20913:SF7">
        <property type="entry name" value="RE60063P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20913">
        <property type="entry name" value="TBC1 DOMAIN FAMILY MEMBER 20/GTPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00566">
        <property type="entry name" value="RabGAP-TBC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00164">
        <property type="entry name" value="TBC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47923">
        <property type="entry name" value="Ypt/Rab-GAP domain of gyp1p"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50086">
        <property type="entry name" value="TBC_RABGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0343">GTPase activation</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rab-GAP TBC" evidence="2">
        <location>
            <begin position="42"/>
            <end position="226"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022468"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ84662.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="364" mass="42788" checksum="2397A31CC15CA49D" modified="2016-11-30" version="1">MNHKDSVAISLRRAGQRKQVLEAIHKKDWNALKRLARAPDGYVDDRLRNYVWPILLHTQHGTYIAEKGSEKDLADPVQVAKDVERSLYYYPQDVTPTFKAHKQQELHCMIIEILWRNPSLKYYQGFHDICTCFLLVLGKKAAIPAVENVALFFIRDAMLDSFEPVSKQLRLMSSMIEYEDPQLSLFLEKANVMSYYALSWILTWFSHDFEDYEKVIRLFDLFLSSQAFMPVYVASAITLLRRDEIMQTEKDLVHSLVTHIPQEMDIERVIQKAIVLEAKYSLLYLQKQSGIWLHQDSVINTWEKDWSSLTWDQVPDHLQANSYLAQNVEKEAWEDEMLTQWTINRRKHIEEEDEFSFVSVAHAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N6E8</accession>
    <name>A0A1C7N6E8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">H/ACA ribonucleoprotein complex subunit CBF5</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">H/ACA ribonucleoprotein complex subunit cbf5</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="primary">cbf5</name>
        <name evidence="11" type="ORF">A0J61_07217</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a uridine in mRNA = a pseudouridine in mRNA</text>
            <dbReference type="Rhea" id="RHEA:56644"/>
            <dbReference type="Rhea" id="RHEA-COMP:14658"/>
            <dbReference type="Rhea" id="RHEA-COMP:14659"/>
            <dbReference type="ChEBI" id="CHEBI:65314"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>uridine in 5S rRNA = pseudouridine in 5S rRNA</text>
            <dbReference type="Rhea" id="RHEA:47036"/>
            <dbReference type="Rhea" id="RHEA-COMP:11730"/>
            <dbReference type="Rhea" id="RHEA-COMP:11731"/>
            <dbReference type="ChEBI" id="CHEBI:65314"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>uridine in snRNA = pseudouridine in snRNA</text>
            <dbReference type="Rhea" id="RHEA:51124"/>
            <dbReference type="Rhea" id="RHEA-COMP:12891"/>
            <dbReference type="Rhea" id="RHEA-COMP:12892"/>
            <dbReference type="ChEBI" id="CHEBI:65314"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the pseudouridine synthase TruB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000477">
        <property type="protein sequence ID" value="OBZ84723.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N6E8"/>
    <dbReference type="FunCoup" id="A0A1C7N6E8">
        <property type="interactions" value="995"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N6E8"/>
    <dbReference type="InParanoid" id="A0A1C7N6E8"/>
    <dbReference type="OrthoDB" id="10250002at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031429">
        <property type="term" value="C:box H/ACA snoRNP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009982">
        <property type="term" value="F:pseudouridine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000495">
        <property type="term" value="P:box H/ACA sno(s)RNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990481">
        <property type="term" value="P:mRNA pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031118">
        <property type="term" value="P:rRNA pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031120">
        <property type="term" value="P:snRNA pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02572">
        <property type="entry name" value="PseudoU_synth_hDyskerin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd21148">
        <property type="entry name" value="PUA_Cbf5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.2350.10:FF:000001">
        <property type="entry name" value="H/ACA ribonucleoprotein complex subunit CBF5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2350.10">
        <property type="entry name" value="Pseudouridine synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.130.10">
        <property type="entry name" value="PUA domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012960">
        <property type="entry name" value="Dyskerin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020103">
        <property type="entry name" value="PsdUridine_synth_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002501">
        <property type="entry name" value="PsdUridine_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002478">
        <property type="entry name" value="PUA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015947">
        <property type="entry name" value="PUA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036974">
        <property type="entry name" value="PUA_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004802">
        <property type="entry name" value="tRNA_PsdUridine_synth_B_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032819">
        <property type="entry name" value="TruB_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004521">
        <property type="entry name" value="Uncharacterised_CHP00451"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00425">
        <property type="entry name" value="CBF5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003280">
        <property type="entry name" value="PRK04270.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00451">
        <property type="entry name" value="unchar_dom_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23127">
        <property type="entry name" value="CENTROMERE/MICROTUBULE BINDING PROTEIN CBF5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23127:SF0">
        <property type="entry name" value="H_ACA RIBONUCLEOPROTEIN COMPLEX SUBUNIT DKC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08068">
        <property type="entry name" value="DKCLD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01472">
        <property type="entry name" value="PUA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16198">
        <property type="entry name" value="TruB_C_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01509">
        <property type="entry name" value="TruB_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01136">
        <property type="entry name" value="DKCLD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00359">
        <property type="entry name" value="PUA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55120">
        <property type="entry name" value="Pseudouridine synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88697">
        <property type="entry name" value="PUA domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50890">
        <property type="entry name" value="PUA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0413">Isomerase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Dyskerin-like" evidence="10">
        <location>
            <begin position="17"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="domain" description="PUA" evidence="9">
        <location>
            <begin position="266"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="424"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="446"/>
            <end position="469"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001166"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001896"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00008999"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00019272"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00072225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM01136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="OBZ84723.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="469" mass="52206" checksum="7E9ED16AE913337A" modified="2016-11-30" version="1">MADNSVIKPTASAPAIDTSNWPLLLKNYDQLNVRTGHYTPIPSGCSPLKRPLDEYVRYGVINLDKPANPSSHEVVAWIKRILRVEKTGHSGTLDPKVTGGLIVCVDRATRLVKSQQGAGKEYVCILRLHDAIESEKKLSQAIETLTGALFQRPPLISAVKRQLRVRTIHESKLIEFDNDRHLAVFWASCEAGTYMRTLCVHLGLLLGVGGHMQELRRVRSGTTSENDDIVTMHDVMDAQWLYDNTKDESYLRRVIRPLESLLTNYKRVVVKDSAVNAICYGAKLMLPGLLRFESGIEINDEIVLMTTKGEAIALAYAQMTTAVMATCDHGVVAKVKRVIMERDTYPRRWGLGPVALAKKKLKTEGKLDKYGRITDETPSTWKSTYVDYANNPDGKQPEPVFGTSTEAVAAAAGMAPKITVLDVAAKDSGATKRPAEEQLDDEHDNKKAKKEKKEKKEKKEKKKEKKSKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N6F0</accession>
    <name>A0A1C7N6F0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Pre-mRNA-splicing factor srp1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">srp1_0</name>
        <name evidence="6" type="ORF">A0J61_07275</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000482">
        <property type="protein sequence ID" value="OBZ84680.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N6F0"/>
    <dbReference type="FunCoup" id="A0A1C7N6F0">
        <property type="interactions" value="76"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N6F0"/>
    <dbReference type="InParanoid" id="A0A1C7N6F0"/>
    <dbReference type="OrthoDB" id="5970at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071011">
        <property type="term" value="C:precatalytic spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005685">
        <property type="term" value="C:U1 snRNP"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071004">
        <property type="term" value="C:U2-type prespliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030619">
        <property type="term" value="F:U1 snRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051183">
        <property type="entry name" value="U1_U11-U12_snRNP_70-35kDa"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13952">
        <property type="entry name" value="U1 SMALL NUCLEAR RIBONUCLEOPROTEIN 70 KD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13952:SF5">
        <property type="entry name" value="U1 SMALL NUCLEAR RIBONUCLEOPROTEIN 70 KDA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="5">
        <location>
            <begin position="5"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="88"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="97"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="126"/>
            <end position="135"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OBZ84680.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="152" mass="18105" checksum="A1D57EEB35F3E3FF" modified="2016-11-30" version="1">MKQRTTLFVSGFDIKTRARNLAYEFERYGRLVRLDIPAPKNYNSKPYAFVEFETNQDAEDAYQEMNGRTIDGYTLSIQWARTTPAYLQNHQRTYPKYNRDNRSRSPYRRERSPSSPPRYDNAIHSAPHRRMRSRSRSPSGYQRRYSQSPPIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N6U7</accession>
    <name>A0A1C7N6U7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Nuclear fusion protein KAR5</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">A0J61_07164</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 11">Required for nuclear membrane fusion during karyogamy.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="11">Endoplasmic reticulum membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="11">Nucleus membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the KAR5 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000469">
        <property type="protein sequence ID" value="OBZ84781.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N6U7"/>
    <dbReference type="InParanoid" id="A0A1C7N6U7"/>
    <dbReference type="OrthoDB" id="5311848at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031965">
        <property type="term" value="C:nuclear membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000742">
        <property type="term" value="P:karyogamy involved in conjugation with cellular fusion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048288">
        <property type="term" value="P:nuclear membrane fusion involved in karyogamy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007292">
        <property type="entry name" value="Nuclear_fusion_Kar5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28012">
        <property type="entry name" value="NUCLEAR FUSION PROTEIN KAR5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28012:SF1">
        <property type="entry name" value="NUCLEAR FUSION PROTEIN KAR5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04163">
        <property type="entry name" value="Tht1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 11" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="9" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="3 11" id="KW-0415">Karyogamy</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10 11" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 11" id="KW-0732">Signal</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022459"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU368082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="OBZ84781.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="14">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="439" mass="51053" checksum="BDD48857A9FDE7D8" modified="2016-11-30" version="1">MLSFVFTFDRKENSNKNLFEQRSTHVLYHLELYRQLQNQESDCYKKVTAELLEGCYSLNLNSVQHIQYAIKLALCELSLAQLKIPIECHSTDARNLKNCVRKLSYSPQTWTSYSGYFRDVAKNFEILYQQQKHLIEWQQQEIALLDQLRGSQSRLIDQLEHIRAAHLKSANQIQSIFESLVLLEDQADLIVSKYNQVITHQVQSASLQLKELSLQHQIELDRMANLITSSLEAADRQLWTIIRGMTQVTENVEKTVQLQTIYFEDWSKIMSSINSQLSEALNHTSSINDRITLINEHVSWFSSLLISPKQWAHIVVSNLKDGALATLSYAIVFYNLYRSMSVTFWKRIALAIFTTTGKYDLGLFETHWSKLVVALIQFVLVQYFPVIKRYRSDLRQPTYFHPEAVISASTPVSAPVYHFQSYYPPYSLDHEFALKNEME</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N6Z2</accession>
    <name>A0A1C7N6Z2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_07534</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000513">
        <property type="protein sequence ID" value="OBZ84416.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N6Z2"/>
    <dbReference type="InParanoid" id="A0A1C7N6Z2"/>
    <dbReference type="OrthoDB" id="2288643at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ84416.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="126" mass="14510" checksum="7B299EE62670BE3A" modified="2016-11-30" version="1">MRLSLKLDDMSSLEDIKKQKTKIEIIESLIRLLKVMRESINLNSETSVSKSTVPAVFDAIAQTGYVPTNLPYFQWKGYVVDRNHSIYSTPDECVREFENILNSYSLSVEGNWRRSLLITAPIQIIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N6Z6</accession>
    <name>A0A1C7N6Z6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Calcium/calmodulin-dependent protein kinase kinase 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">Camkk2</name>
        <name evidence="10" type="ORF">A0J61_07527</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="7">Belongs to the protein kinase superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000512">
        <property type="protein sequence ID" value="OBZ84426.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N6Z6"/>
    <dbReference type="FunCoup" id="A0A1C7N6Z6">
        <property type="interactions" value="127"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N6Z6"/>
    <dbReference type="InParanoid" id="A0A1C7N6Z6"/>
    <dbReference type="OrthoDB" id="68483at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd14008">
        <property type="entry name" value="STKc_LKB1_CaMKK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000571">
        <property type="entry name" value="Maternal embryonic leucine zipper kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43895">
        <property type="entry name" value="CALCIUM/CALMODULIN-DEPENDENT PROTEIN KINASE KINASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43895:SF150">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE STK11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 10" id="KW-0418">Kinase</keyword>
    <keyword evidence="3 6 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 7" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="9">
        <location>
            <begin position="43"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="72"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OBZ84426.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="414" mass="46952" checksum="86843501A2C0EAF3" modified="2016-11-30" version="1">MSSPSPSPSSSSARRHHSPPVIRETLGATTSETKEGLRKINNYLLKKEIGRGAFGTVHLGIDEITQNEYAIKEFSKSRLRKKEQMDLFRSGRGRGRARMTGLGVHNRQQQKEPENPLNLIRGEMAVLKKLNHPHIVRLYEVLDDPSGDSIYMVFEMMHQGVLMTIEVDQVATPYTPDVARRYFKEMMLGIEYLHANDIVHRDIKPDNLLLSKEDVLKIVDFGVSEMFVKGNDRLKKSAGSPAFMAPELCVAKHGEVSGKAADIWSMGVTLYCMIFGKTPFNSTNILELYEMINEASIEYNDTIDDDLLDLFHKILDRNPDTRITMKELREHPWITNNGTETMLSEEDNCDIVSEVTEEEMNNAIKSIASIFAVIKAVSKFKRHSRSLSQKSLNQIMQDPDEVTVVKATEELHIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N714</accession>
    <name>A0A1C7N714_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Chitin deacetylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">CDA_5</name>
        <name evidence="4" type="ORF">A0J61_07103</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000462">
        <property type="protein sequence ID" value="OBZ84847.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N714"/>
    <dbReference type="InParanoid" id="A0A1C7N714"/>
    <dbReference type="OrthoDB" id="407355at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004099">
        <property type="term" value="F:chitin deacetylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009272">
        <property type="term" value="P:fungal-type cell wall biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.370">
        <property type="entry name" value="Glycoside hydrolase/deacetylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011330">
        <property type="entry name" value="Glyco_hydro/deAcase_b/a-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002509">
        <property type="entry name" value="NODB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050248">
        <property type="entry name" value="Polysacc_deacetylase_ArnD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10587:SF133">
        <property type="entry name" value="CHITIN DEACETYLASE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10587">
        <property type="entry name" value="GLYCOSYL TRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01522">
        <property type="entry name" value="Polysacc_deac_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88713">
        <property type="entry name" value="Glycoside hydrolase/deacetylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51677">
        <property type="entry name" value="NODB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NodB homology" evidence="3">
        <location>
            <begin position="156"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="344"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OBZ84847.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="344" mass="39500" checksum="0F784BF6137DDAAA" modified="2016-11-30" version="1" fragment="single">MRGSIDVEEIDRIVLFLHVIYINKTHAQSFSFAKLDKYDRAPVILPVSSPTFLPQFPFHGTRPLQPVPTGPLEPHPNFNAHAYPPFWKTPDSRHREVQAAIRAINWDYVPKLARHLSQNDTYEIQKAEGCWETNKLCSTPKVTYLPNDVIECARPYDFGLTFDDGPLITNASNRIDRMPYLYDFLASLNQTATLFIDSPQAALRAFQSGHTLCAHTWSHTHMTMLTNEQIVAELYWTIRAIKEATGVTTRCWRPSYGDVDDRVRAIAHQLGLRTITWNSDSLDWYISLANDAEDFIRDEVDAAFKSWISAYQSGNQTHGRIVLMHESTQQTIKVARKWIPRLKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N7W3</accession>
    <name>A0A1C7N7W3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_06740</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000421">
        <property type="protein sequence ID" value="OBZ85220.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="InParanoid" id="A0A1C7N7W3"/>
    <dbReference type="OrthoDB" id="2270879at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ85220.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="109" mass="12577" checksum="66D1A784D94AE126" modified="2016-11-30" version="1" fragment="single">MKLGFVFTSPNFHVFDLCVYISTNNNFFYKDGQDEQGNDAVEWKEEVDPYNLGTLLTLSQYXAFQSRFPINDTEELGVQMEELAEELSQTEANGKKYNAYSDSQNSVFY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N846</accession>
    <name>A0A1C7N846_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="9">F-box-like/WD repeat-containing protein TBL1XR1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">Tbl1xr1</name>
        <name evidence="9" type="ORF">A0J61_06709</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000419">
        <property type="protein sequence ID" value="OBZ85241.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N846"/>
    <dbReference type="FunCoup" id="A0A1C7N846">
        <property type="interactions" value="202"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N846"/>
    <dbReference type="InParanoid" id="A0A1C7N846"/>
    <dbReference type="OrthoDB" id="1367865at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034967">
        <property type="term" value="C:Set3 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003714">
        <property type="term" value="F:transcription corepressor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.960.30:FF:000001">
        <property type="entry name" value="F-box-like/WD repeat-containing protein TBL1XR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.10:FF:000218">
        <property type="entry name" value="WD40 repeat-containing protein HOS15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.960.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045183">
        <property type="entry name" value="Ebi-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006594">
        <property type="entry name" value="LisH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22846:SF2">
        <property type="entry name" value="F-BOX-LIKE_WD REPEAT-CONTAINING PROTEIN EBI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22846">
        <property type="entry name" value="WD40 REPEAT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08513">
        <property type="entry name" value="LisH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00667">
        <property type="entry name" value="LisH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50896">
        <property type="entry name" value="LISH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="4" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="2 7" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="7">
        <location>
            <begin position="167"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="7">
        <location>
            <begin position="219"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="7">
        <location>
            <begin position="260"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="7">
        <location>
            <begin position="343"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="7">
        <location>
            <begin position="385"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="7">
        <location>
            <begin position="431"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="92"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="111"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OBZ85241.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="508" mass="56961" checksum="DBC02E14433AD813" modified="2016-11-30" version="1">MVLTSEEVNIIVYKYLQESGFRHTSFAFQYESQVEKSIYRDAQIQPGALINIIHKGLQFMEIEAHMNEDGELMECSVPFSLLEPHHCELTGNTFNSEPMSIKPPTSAKRQRKEEKKQKDREKRARRENIEEEIDGRIKEENGGASSAMEDVVKEEPTAIKEDHVTVLKGHKSEVFSCAWNPVLPSLLASGSGDATARLWNVPANKDEATEPIVLNHLPNLNDNKDVTTLDWNPSGTLLVTGSYDGQARIWTQKGQLRFVMGHHSGPIFSLKWNMRGDLVLSGSADTTTIVWDPETGEMKQQFEIHSLAILDVDWMDNTTFASCSSDKTIYVCRVGSPKPLKKWIGHEDEVNAVRWDPSGQYLASCSDDMTTKIWSLSSDEPVREIKGHNLQIYTIQWAPYTNNSPRILATASFDATVRLWDALKGTCLHVLKNHSEAVYSISFSPDARLLASGSFDEVLNVWDTKDGTLKKTFKANGGIFEVHFNKTGDKIAACTSNKQVVILNNIQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N852</accession>
    <name>A0A1C7N852_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_06815</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000429">
        <property type="protein sequence ID" value="OBZ85138.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N852"/>
    <dbReference type="InParanoid" id="A0A1C7N852"/>
    <dbReference type="OrthoDB" id="2439595at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="1"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="409"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="77"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="8"/>
            <end position="19"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ85138.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="438" mass="50802" checksum="A3E9195EBB75DF01" modified="2016-11-30" version="1">MSDKEPTITASSTKETSYSQEEDAADRSSQEEQTLTTPRRKPSVHSFRVMEAKESESDKDLVIHSLNESLHIHKEILEKIQSEKEAYHQQIEKERELEKQQADSWRQASERALEEQLNRCSELEYSISQLRRELEIKKEDYKKLEVKFYSYVKQIRVTDDDLSTIQPEISHLLSQLNNTCMGLKSKMNREQGTIFVFKHWEHRTDLIRKYMIPSGNDSDLLDTSYITFFVEKYLIHTLLQRILDVPIHLGVSINDSFQEVNEWMASRNKEWANRLRQQVCALVVQQPGDEEKGIADARQQLLDEIVEELHPVYPSLKQDPKKIENLISRASKLNLAIKGQEIKIERLPIEEGVTRFDGETMKATAKGKPDGIVFLSITPTFVARDEVDNEHGFTIPGKVFCIEEVTDHMEEDQHTPDVDKDIKENTSHEEESDDESSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N8I1</accession>
    <name>A0A1C7N8I1_9FUNG</name>
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        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_06554</name>
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    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
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            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000401">
        <property type="protein sequence ID" value="OBZ85393.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N8I1"/>
    <dbReference type="InParanoid" id="A0A1C7N8I1"/>
    <dbReference type="OrthoDB" id="2247662at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ85393.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="93" mass="11161" checksum="0C2941DBD1A223C4" modified="2016-11-30" version="1">MQHSVQYHQHITLREFLYQLMNTFKHSFDSKAHRTSHSCQSEVEKANAKLSQFEKTYVSFPEFVDIDAEDGRRRFNQEEADARHWFQHKTLAC</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N8U4</accession>
    <name>A0A1C7N8U4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_06460</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000390">
        <property type="protein sequence ID" value="OBZ85487.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N8U4"/>
    <dbReference type="STRING" id="101091.A0A1C7N8U4"/>
    <dbReference type="InParanoid" id="A0A1C7N8U4"/>
    <dbReference type="OrthoDB" id="2358153at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="123"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="211"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
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            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="221"/>
            <end position="235"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ85487.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="417" mass="47301" checksum="E27DE5C03731A1D9" modified="2016-11-30" version="1">MHYQPHRSEGHSPSTPLPANRPLSTRKNACIVCAVCFTCSGYYGSNCHCPEIQPRRGKNLPEGGLDSRAKKLSPLDKDDYDFTIQWLDEFTHTVYRDSHRRVHLRDLTEVSLCKAHSSTLYRAKKKHQRMQQQAPPSPADSMMEDITRHRSSSVDSYPHLPQPQCSTIHEDKLPYHENNGLMGGPLAAKVREISCQFAYPKESPDLFMITTSHSHKRKRTSTLSRPSPSASTPLYSNPPLQRHPLPPPPSSHSFSSQLPPLHLRTPSLSSLSNNLQHQLHVSNAYHHVFHDKDTNHHHSLDLPPPYTKTIETVSLKSSPTLKSIDLHSQVKENDEGVYFVKNLAITDAYTFQDLLSEIDFAGSPPAGKRLVISDKKRERIFPLGQAIRSVIRFPRDTHVEFYLGLSDKASINWNHYQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N9M8</accession>
    <name>A0A1C7N9M8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Btz domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_06101</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000352">
        <property type="protein sequence ID" value="OBZ85843.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N9M8"/>
    <dbReference type="STRING" id="101091.A0A1C7N9M8"/>
    <dbReference type="InParanoid" id="A0A1C7N9M8"/>
    <dbReference type="OrthoDB" id="3361414at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="167"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="221"/>
            <end position="641"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="691"/>
            <end position="772"/>
        </location>
    </feature>
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        <location>
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            <end position="894"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="976"/>
            <end position="1047"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="23"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="45"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="80"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="107"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="173"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="194"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="221"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
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            <begin position="284"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="308"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="333"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="376"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="386"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="410"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="497"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="566"/>
            <end position="590"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="591"/>
            <end position="600"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="694"/>
            <end position="711"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="727"/>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="746"/>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="803"/>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="857"/>
            <end position="871"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="880"/>
            <end position="894"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1020"/>
            <end position="1047"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ85843.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1047" mass="119272" checksum="1C79B5A9966BC5E0" modified="2016-11-30" version="1">MSRLLRSRRGHISEGEEDDYGSDSYSITTNSFSDSDSERDYTDGSSDEEYTDSEEETVTEEEDETEEEEDDSDAEEDQSQPVTSSQQQALVSNTTEDVEPNFQQSSHTKDPNIVKEEEIDYQSHYDDKEKRIQEHREYRRKLVEDPSFVPYVGSFWGHDDRYREDLLTETRAESSQPYFSNNHASNGHTAGGSRNHDGNRHDIDPLMYKKWDHSGYEELLRMDEEDERRKRSLIEAGKTEELANFRPYRPRYHNNHNQHYSRGPRNYKGHGSGDQRSPHRQQRTQHEEWPELSHNSQEKLNETATVNKEQRDEWSQPPKDDHGWGNALVTGIEEIKLEENGWKEESKGWKEESTGWGDTATNENNDGWSKPSPSSPDKHGWDSTDKTIVSNDNQPDQNNWSASENQAVTDDLKDHTDWSNTKFSERNSDRHSPSDKQRKVQPNIPNEEKASSSWTLNAVPEIEVPTTPSKWTTRSDRGRGRFNNNDNYQNRPRRDHRNTEDSWRPKKAEQEEQITQEWKADNLDPSPVTNSPAISSVRWDKPDTTTTTAENGWGESVATTDDNKGATATNGWEASSTVENGTGWNSDMPESNNTNNNSTTQAADPVKEPSAVWNQSKETELQPNAVEVDTKGWGPAPVLESQNKVDSDISWATHTNNNLTDNLQNISSEGTAAGWGDLDVSKLSEDANVGWKTDTNDEKFNNWDTHKESVHHPPRKGRGYLSQKMDAVAPTTATATPSNVSEEDQFSSQQQLSQEATPVMSAWGNFHNGGDEDSDVEIILEAEEEPEWLKQEQVLGMTAPGDMDASASSPYISSSPSMDDSPSKHASRQHYYSQAEYSPRFDSRKPRYNTNSSRPRRQFDESWRRRKDDSPHQGPPLPQQPQQQPVPTYYPTPQHMNGANITYVPMIPNTNYLHMGGNVQPNDSSVNGSNKFYAPLPPGFEANGMVYYGVDPNLYPPVQPFYYYMPINNNNGVMGSSVAYEEPRSPPTQRLQEEDDDEGWGPSPDIGDADTQWKSHNNRHQQNPPNHTVNYNPSPYYYYPQQSQPHF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NAL2</accession>
    <name>A0A1C7NAL2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Transmembrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_05793</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000324">
        <property type="protein sequence ID" value="OBZ86155.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NAL2"/>
    <dbReference type="InParanoid" id="A0A1C7NAL2"/>
    <dbReference type="OrthoDB" id="2352759at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF041646">
        <property type="entry name" value="VC0807_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="36"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="67"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="94"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="124"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="188"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="227"/>
            <end position="247"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ86155.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="288" mass="33467" checksum="151B99F4F10FEBD6" modified="2016-11-30" version="1">MSIPKDSTPLLNKKKVRHVHRVPTFFRSSLPNRRSILRAFVDMVVHMIFELVLPIVLYYVLREFTSPLLALLLAGVPTAMTVLYKGYRERKVDMMGVLMLMGFVVSAILAFVQSDPKLYLLRESAMTLAMGLMLLITMLPLRWGHHFLRPFMFYVARQIAVSSNSLMQRTTVLDHWDWFWHHYSTFRWFLRGLTGIWGLGLISEFLVRVALINALDDVDDVVYYSNIYMLVVMVVLGTITVVSTLLLRHYFNIKQNRIKMAERQSEIERIIARAAAEQEERERQAALA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NB88</accession>
    <name>A0A1C7NB88_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Pyruvate dehydrogenase E1 component subunit beta</fullName>
            <ecNumber evidence="10">1.2.4.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">PDB1</name>
        <name evidence="12" type="ORF">A0J61_05649</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>N(6)-[(R)-lipoyl]-L-lysyl-[protein] + pyruvate + H(+) = N(6)-[(R)-S(8)-acetyldihydrolipoyl]-L-lysyl-[protein] + CO2</text>
            <dbReference type="Rhea" id="RHEA:19189"/>
            <dbReference type="Rhea" id="RHEA-COMP:10474"/>
            <dbReference type="Rhea" id="RHEA-COMP:10478"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:83099"/>
            <dbReference type="ChEBI" id="CHEBI:83111"/>
            <dbReference type="EC" id="1.2.4.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 10">
            <name>thiamine diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58937"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.2.4.1" evidence="10"/>
    <dbReference type="EMBL" id="LUGH01000311">
        <property type="protein sequence ID" value="OBZ86301.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NB88"/>
    <dbReference type="FunCoup" id="A0A1C7NB88">
        <property type="interactions" value="440"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NB88"/>
    <dbReference type="InParanoid" id="A0A1C7NB88"/>
    <dbReference type="OrthoDB" id="10266385at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042645">
        <property type="term" value="C:mitochondrial nucleoid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045254">
        <property type="term" value="C:pyruvate dehydrogenase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004739">
        <property type="term" value="F:pyruvate dehydrogenase (acetyl-transferring) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006086">
        <property type="term" value="P:pyruvate decarboxylation to acetyl-CoA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd07036">
        <property type="entry name" value="TPP_PYR_E1-PDHc-beta_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.920:FF:000001">
        <property type="entry name" value="Pyruvate dehydrogenase E1 beta subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.970:FF:000006">
        <property type="entry name" value="Pyruvate dehydrogenase E1 component subunit beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.920">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.970">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027110">
        <property type="entry name" value="PDHB_mito-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029061">
        <property type="entry name" value="THDP-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009014">
        <property type="entry name" value="Transketo_C/PFOR_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005475">
        <property type="entry name" value="Transketolase-like_Pyr-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033248">
        <property type="entry name" value="Transketolase_C"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006667">
        <property type="entry name" value="PRK09212.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF008854">
        <property type="entry name" value="PRK11892.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11624">
        <property type="entry name" value="DEHYDROGENASE RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11624:SF96">
        <property type="entry name" value="PYRUVATE DEHYDROGENASE E1 COMPONENT SUBUNIT BETA, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02779">
        <property type="entry name" value="Transket_pyr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02780">
        <property type="entry name" value="Transketolase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00861">
        <property type="entry name" value="Transket_pyr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52518">
        <property type="entry name" value="Thiamin diphosphate-binding fold (THDP-binding)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52922">
        <property type="entry name" value="TK C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6 10" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-0630">Potassium</keyword>
    <keyword evidence="9 10 12" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 10" id="KW-0786">Thiamine pyrophosphate</keyword>
    <keyword evidence="4" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="Transketolase-like pyrimidine-binding" evidence="11">
        <location>
            <begin position="43"/>
            <end position="218"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU364074"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM00861"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="OBZ86301.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="373" mass="40193" checksum="3ACEAA0E3241B36E" modified="2016-11-30" version="1">MTFLATLNRMAPSAVKRAATTSIKPTAVALSQKRFNSTAGTQMTVREALNQALEEEMIKDQNVYIMGEEVAQYNGAYKVTKGLLDKFGPKRVIDTPITEMGFAGIAVGSAFCGLKPVCEFMTFNFAMQAIDQIVNSAAKTHYMSGGIVKCPIVFRGPNGAAAGVGAQHSQDFSAWYGSVPGLKVVSPWNSEDAKGLLKAAIRDPNPVVVLENELEYGVSYPMSAEALKDDFVIPIGKAKIEREGKDITIVTHSRTVGFAMKAADDLAKNGISAEVVNLRSIKPLDTETIFKSVKKTNHIITVENAWASFGVGSEIAAQIMESDAFWHLDSPLTRVTGADVPTPYAANLEALAFPDEHVIAKAARDNLDKKIGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NBI4</accession>
    <name>A0A1C7NBI4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Negative regulator of differentiation 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">nrd1_1</name>
        <name evidence="6" type="ORF">A0J61_05834</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000327">
        <property type="protein sequence ID" value="OBZ86119.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NBI4"/>
    <dbReference type="FunCoup" id="A0A1C7NBI4">
        <property type="interactions" value="32"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NBI4"/>
    <dbReference type="InParanoid" id="A0A1C7NBI4"/>
    <dbReference type="OrthoDB" id="6407164at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010494">
        <property type="term" value="C:cytoplasmic stress granule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008266">
        <property type="term" value="F:poly(U) RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031138">
        <property type="term" value="P:negative regulation of conjugation with cellular fusion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000122">
        <property type="term" value="P:negative regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.330:FF:000120">
        <property type="entry name" value="Negative regulator of differentiation 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039171">
        <property type="entry name" value="Cwc2/Slt11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14089">
        <property type="entry name" value="PRE-MRNA-SPLICING FACTOR RBM22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14089:SF8">
        <property type="entry name" value="RNA-BINDING PROTEIN MRN1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 3" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="5">
        <location>
            <begin position="120"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="5">
        <location>
            <begin position="210"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="5">
        <location>
            <begin position="323"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="5">
        <location>
            <begin position="413"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="485"/>
            <end position="511"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="495"/>
            <end position="511"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OBZ86119.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="528" mass="58392" checksum="7E86BC4254A924A5" modified="2016-11-30" version="1">MKRSNDSQTSQAELNLNDDSNKRPRYSQSNYSDMYAQYGLMSQYNAASFPHNAAQYAGYAQPMYGANYNPQYNMMATQYAGYPQGFPTANTTTNAAVAAAAAAAAAATGTGASLTGETSRTIYLGNVTSAILPHDILRHVRHGQVESFRMVPEKNCAFLAFVDPSSAQMFYQDFMTKKLIVKDAEIKIGWGKPSMIPYNLKLSIDNGATRNVYLGRLTQADTEETIQAALARFGPIEQIKLVRDKNIAFVHFLSIIAAVKCVSSLQSDPAWSEKRVNYGKDRCGDLVDPYNAAMALHNPYATAANGFHFDPYSGHNLGNNTQRTLYFGNIHPEASCEDICNAIRGGNLLQIRYFPEKHIAFVTFMDASTANAVYNNCNTFGLAVKGKRVRVGWGKPSSVSTQVAMAVQNGATRNIYIGNICDSHTAEKLRNDFSEYGEIELINVCKEKNCAFVNFTSVSSAINALQGAKTKSGYSQMKLNYGKDRCGNPWRTNKPKADDHKKVPEKKEEPKLETFDELDHFDFEKENA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NBS6</accession>
    <name>A0A1C7NBS6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_05390</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000289">
        <property type="protein sequence ID" value="OBZ86562.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NBS6"/>
    <dbReference type="InParanoid" id="A0A1C7NBS6"/>
    <dbReference type="OrthoDB" id="2256950at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ86562.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="60" mass="6450" checksum="A896551AD2563639" modified="2016-11-30" version="1">MAQQPASAHPTHEPFTSPTEPSKVNNCNCCAIIFAPLAALGGLVDQIMRKCSRLVRGDKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NCG9</accession>
    <name>A0A1C7NCG9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_05490</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000297">
        <property type="protein sequence ID" value="OBZ86459.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NCG9"/>
    <dbReference type="InParanoid" id="A0A1C7NCG9"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="74"/>
            <end position="97"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ86459.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="110" mass="12481" checksum="A9EE2A66019A86A8" modified="2016-11-30" version="1">MIQSYSSLWNEHCGIASFNPLYTVQPHADIVPTDARFIFASVASANDLISPLMHILNIYAPATRQARLPYFRDLATNLSLMSLLRSFTVLIIIIGNFNYDMYQRNILDPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NCZ6</accession>
    <name>A0A1C7NCZ6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Rho-GTPase-activating protein 8</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">rga8_0</name>
        <name evidence="3" type="ORF">A0J61_05507</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000298">
        <property type="protein sequence ID" value="OBZ86446.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NCZ6"/>
    <dbReference type="STRING" id="101091.A0A1C7NCZ6"/>
    <dbReference type="InParanoid" id="A0A1C7NCZ6"/>
    <dbReference type="OrthoDB" id="2155291at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007264">
        <property type="term" value="P:small GTPase-mediated signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.60">
        <property type="entry name" value="Arfaptin homology (AH) domain/BAR domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.555.10">
        <property type="entry name" value="Rho GTPase activation protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027267">
        <property type="entry name" value="AH/BAR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008936">
        <property type="entry name" value="Rho_GTPase_activation_prot"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000198">
        <property type="entry name" value="RhoGAP_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45808">
        <property type="entry name" value="RHO GTPASE-ACTIVATING PROTEIN 68F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45808:SF2">
        <property type="entry name" value="RHO GTPASE-ACTIVATING PROTEIN 68F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00620">
        <property type="entry name" value="RhoGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00324">
        <property type="entry name" value="RhoGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103657">
        <property type="entry name" value="BAR/IMD domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48350">
        <property type="entry name" value="GTPase activation domain, GAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50238">
        <property type="entry name" value="RHOGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rho-GAP" evidence="2">
        <location>
            <begin position="244"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="556"/>
            <end position="591"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="567"/>
            <end position="591"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="591"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50238"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ86446.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="591" mass="68361" checksum="E41E624AF8C11C1D" modified="2016-11-30" version="1" fragment="single">MTRSVYWSRCRAFKSVCPQFRPNINLTNQPLLQTLKSLSDQEMILSKEFVLRRLANESHINDSTSQDVWQNLLVLGFVKSVEDGYKLQHDIIDYYIKQPTKDWGQLLSVFRSAHPSEAVYKAYMEMLRSERAYKEKVLSTDNMRMQLEEKLLDCFDQMEQWEKKRMRILKEATKALHSMVTTFSSSTSIISQTYDQMSLFQEAISPEQDISCIVQQYKTSPFCPKPFIFENFFDDQASHQMFGVPIEQTTKLHKTYVPPIVSCAMQLIEQDIEALPSEEKHNRIKHIWCQTKEMKDINKACKELNDLSNSSYEELLTALKLYDVCTLANVIRVYLLELPECLLTYDFYETVKILYSGQQDDEESRIVSTAKLLSTLPSANYHTIKAFCRHMSRLLAYQTSDKLLQTICSLFSYVLLRPRQYSSTNVHDRHPKRLLRDLLIFYDKVFTQETDNSQEKNASRLTITAEVYLSQDASLPPPPPPKDTCGFHLAHSNDTKARSHSSLNGIPIVPHSSVTLFEDPEYSQVSTPTYQTFDIQYGNGLNPERLSTDISFVLDSEVSDDSSQTRTSEHDSFSTKEMLDNIDLEENRPYA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7ND87</accession>
    <name>A0A1C7ND87_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Cell division cycle-related protein res2/pct1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">res2_0</name>
        <name evidence="6" type="ORF">A0J61_05022</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000260">
        <property type="protein sequence ID" value="OBZ86930.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7ND87"/>
    <dbReference type="STRING" id="101091.A0A1C7ND87"/>
    <dbReference type="InParanoid" id="A0A1C7ND87"/>
    <dbReference type="OrthoDB" id="6718656at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030907">
        <property type="term" value="C:MBF transcription complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033309">
        <property type="term" value="C:SBF transcription complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001228">
        <property type="term" value="F:DNA-binding transcription activator activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.260.10">
        <property type="entry name" value="Transcription regulator HTH, APSES-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036887">
        <property type="entry name" value="HTH_APSES_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018004">
        <property type="entry name" value="KilA/APSES_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051642">
        <property type="entry name" value="SWI6-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003163">
        <property type="entry name" value="Tscrpt_reg_HTH_APSES-type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43828">
        <property type="entry name" value="ASPARAGINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43828:SF3">
        <property type="entry name" value="CHROMO DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13637">
        <property type="entry name" value="Ank_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04383">
        <property type="entry name" value="KilA-N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM01252">
        <property type="entry name" value="KilA-N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54616">
        <property type="entry name" value="DNA-binding domain of Mlu1-box binding protein MBP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51299">
        <property type="entry name" value="HTH_APSES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="6" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="6" id="KW-0132">Cell division</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="HTH APSES-type" evidence="5">
        <location>
            <begin position="6"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="215"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="108"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="462"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="116"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="142"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="477"/>
            <end position="486"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51299"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OBZ86930.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="587" mass="66711" checksum="46DDE172174B7F14" modified="2016-11-30" version="1">MSSGKVYAAVYSGVLVYEMMIHGIATMVRGEDSYLNATQILKVAGFEKTRRSKILEREVLIGEHEKVQGGYGKYQGTWIPFEKGKELAERYEVLDSLMPLLTFDPSTLKQDEDTQEGNSQTNALSPLPSNKSRAVAPTSPKSQKRPKQIIQPQRKRQRLEGAPPEPISSEDAFYEHHRSLLMSLFLTDNPEDVPSLFASILLTKDLNIDLVIDDQGHTALHWAAALGRVRVVELLIENGANVCRVNYQGETPLMRAAMITCCYENKCFTEMVEMLADSTHVTDNRGRTVLHHIALTATVEGFTDAAIYYMKRFVKAVPKKSILKNILNIKDTQYYESALAIALRVECQEIADVLVKQGAIDPLLTRAEEDEEVEFDPVDYKAKSKAPDALKSIQSIIEKLEEDYHEQLKKKDLIAFELRRELGIMKYELREAQRRLEFPVSMQLAEARKKISQLEAKLAEDEQASELKTDQEEEESNDKSVKERKLEKKLKSLQHQVEASNKTIKRLQHDLETERKQAHEKEMEYRRLIAVSCGLPIERVDSLIQPLTLAVESDPPDFDMVKVIGFMENQNQQQKANLHSPNNSTPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NDB8</accession>
    <name>A0A1C7NDB8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Peptide hydrolase</fullName>
            <ecNumber evidence="13">3.4.-.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">A0J61_04868</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">May be involved in vacuolar sorting and osmoregulation.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Vacuole membrane</location>
            <topology evidence="3">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 13">Belongs to the peptidase M28 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.-.-" evidence="13"/>
    <dbReference type="EMBL" id="LUGH01000249">
        <property type="protein sequence ID" value="OBZ87077.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NDB8"/>
    <dbReference type="FunCoup" id="A0A1C7NDB8">
        <property type="interactions" value="19"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NDB8"/>
    <dbReference type="InParanoid" id="A0A1C7NDB8"/>
    <dbReference type="OrthoDB" id="76293at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005774">
        <property type="term" value="C:vacuolar membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008235">
        <property type="term" value="F:metalloexopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.10">
        <property type="entry name" value="Zn peptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045175">
        <property type="entry name" value="M28_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007484">
        <property type="entry name" value="Peptidase_M28"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12147">
        <property type="entry name" value="METALLOPEPTIDASE M28 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12147:SF58">
        <property type="entry name" value="VACUOLAR MEMBRANE PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04389">
        <property type="entry name" value="Peptidase_M28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53187">
        <property type="entry name" value="Zn-dependent exopeptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="8 13" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="14" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="6 13 16" id="KW-0645">Protease</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 14" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10 14" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0926">Vacuole</keyword>
    <keyword evidence="9 13" id="KW-0862">Zinc</keyword>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="162"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="203"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="240"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="275"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="300"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="332"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="370"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="400"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M28" evidence="15">
        <location>
            <begin position="2"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="16">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00003273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022554"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU361240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF04389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="OBZ87077.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="637" mass="70807" checksum="FBE8F2579C067BF2" modified="2016-11-30" version="1" fragment="single">GGLIGADAFALHPWFSTIKLFVNLEGTGAGGRALLFRSNIMSAVESLASNAYYLHGSMLGNSLLQSRLLRSDTDYTTFSKHGVPGLDISFYYPRSHYHTQRDDLAHTTPESLQHMGQMALGAVLGIDETNAIVEQAGKPEPFIYYDILGRFMLVYSFSTCQLLNLLALVVIPLGFLGLFWTSRSQEEDRKAILKQNVVLIGQSLIATLVAVVLMVVFITLSCLLLLWINPSVTYGSTYFVAVYLFAASFLSLVLSQWILLTYSKTMAHQLTTAQTGLYGLTSFWWLLLLVATILTSQGYAASYFAIYFFVSSALATGLLANTVDSEEEGSRYWSVAFLVQVVLPVTLMTEFLLLVVDSLRHTTADGTPEWAIYGLLATPIVIVVLHLLPWVYAAGDLRRTTFFASLVFVVIMVLCLLISPFDGQISPNRIVFRQEHDVVSNISTVTLVTGTSFGLADKAKEMLSSSEYDSMVCEPYLTYQTRCTYQTDLIPLYARDPQKEIHVAYDSVDCNKKVCRLKIKTQVQHSLLCQLEFTQTDIQGLEAKLNGHWVKQIGNQSIHALTVYSKEQASQVAWDLVYDVDQDHVGEAIFSCIYDDWTEGELPAFTTLKNNLPHYALLTMTGGVGLAKVHYTPISLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NDL5</accession>
    <name>A0A1C7NDL5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_04781</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000241">
        <property type="protein sequence ID" value="OBZ87175.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NDL5"/>
    <dbReference type="InParanoid" id="A0A1C7NDL5"/>
    <dbReference type="OrthoDB" id="5573882at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="97"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="101"/>
            <end position="119"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ87175.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="276" mass="31499" checksum="A1A2234B69C63D87" modified="2016-11-30" version="1">MVTLQKKQWLPYGTIPKRTNKKTKPPASVLPTTTPYPFFLPKTDSIFSFFSHLFSDCKAENGPVGFMPCVTPTQTQTSPFDVIAVSSPIDCSYHAHDHDSSSSYSSSSSSSESSLSSYMESEERKNTITTTHALSDILCDHYVQTKQNAPSSADSELINVPLETFRIFEAPPTEEQYWMETTDREWTLVETLSKPSKRLQKILDQQEPEEKKIPPKPLVYHDRDIRSNTAYLRMIVAEVNMMRSQKIVGPLRPRRVLPKRTDRFMHRPSPLQLVLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NDW3</accession>
    <name>A0A1C7NDW3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_04675</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000233">
        <property type="protein sequence ID" value="OBZ87272.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NDW3"/>
    <dbReference type="InParanoid" id="A0A1C7NDW3"/>
    <dbReference type="OrthoDB" id="2289831at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="92"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="132"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="18"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ87272.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="153" mass="17431" checksum="EC4EE6170964BD38" modified="2016-11-30" version="1">MSKAYYNNNNTSDVDQEAPPPAYQETPPFNPNYQPPFHPSSSQPLYPQIPSAPQLVTPNTQVRYQTIEMPSAEPVQISTQRRHQLIAEHRKFPLAAIFFLFGWFCPPLWVIGACCCAGSRNPYESFWGKANFFMAMVMIITSVIYSMIAMNDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NEG6</accession>
    <name>A0A1C7NEG6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Calmodulin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">CALM_1</name>
        <name evidence="5" type="ORF">A0J61_04447</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000218">
        <property type="protein sequence ID" value="OBZ87495.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NEG6"/>
    <dbReference type="STRING" id="101091.A0A1C7NEG6"/>
    <dbReference type="InParanoid" id="A0A1C7NEG6"/>
    <dbReference type="OrthoDB" id="26525at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00051">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.238.10:FF:000001">
        <property type="entry name" value="Calmodulin 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050145">
        <property type="entry name" value="Centrin_CML-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23050">
        <property type="entry name" value="CALCIUM BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13499">
        <property type="entry name" value="EF-hand_7"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00054">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0106">Calcium</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="EF-hand" evidence="4">
        <location>
            <begin position="16"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="4">
        <location>
            <begin position="88"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="4">
        <location>
            <begin position="124"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="159"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="176"/>
            <end position="186"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OBZ87495.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="186" mass="21087" checksum="DD7A85B1834432CB" modified="2016-11-30" version="1">MGSKRISLGSHFLSRKKKQDLSELFTSFDRDKDGKISTSELKEMLNSACVDDPAVQNMVASQPDGSLDFEDFANLMRSTLSDPHRMTSKQLELKEAFDAFDKDGDGVINVTELQAMMEKLGDKLSLQEAEDLIQDVDLDRDGVVSFNEFCIMMGVKQPTEPIVKRSPDQPSQQRFSIKRFFRSHKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-06-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NER3</accession>
    <name>A0A1C7NER3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_04346</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000211">
        <property type="protein sequence ID" value="OBZ87595.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NER3"/>
    <dbReference type="InParanoid" id="A0A1C7NER3"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ87595.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="113" mass="12894" checksum="35BB49F403B09BFF" modified="2016-11-30" version="1">MGYLNSNISSDNEFAVWFSAFCQGAREADKKAEKGDAKAVWDKMITKHEISTFNLTINTRHKKVVCGDHGPDDVEIKEWLVEGADMRSTFKAKRKEVVSLVKQDKPIKENEYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NFH0</accession>
    <name>A0A1C7NFH0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_05864</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000330">
        <property type="protein sequence ID" value="OBZ86084.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NFH0"/>
    <dbReference type="InParanoid" id="A0A1C7NFH0"/>
    <dbReference type="OrthoDB" id="2284791at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="253"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="253"/>
            <end position="270"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ86084.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="479" mass="55700" checksum="DC5BE72C2AFCEEE9" modified="2016-11-30" version="1">MVYIGQEDLHNFLRSQENYNLEAFLRQHEQLISSTNSYNSWEKLRTTWVMRYKAALKEVKPELKHISRKLTAVEDTFWQQLYRKVNMVQNGELRIELLDWCTQLMCKKPVTVQTEAIKDKINRLEEENSNALVDRLNIMSFKLLNSFDTLTPIEKCLLKLSVSNVINMSKKVYSDQYQKHFSLSLYESLSSLSPPTLTLSYEQQLQTHFAEFKKIIFEESEAMVPMAIAKRGLKDQICYVMIYLRNKMAEWEDNDEGKDDDEDEENDDEAESAREKKRKRVETTSENDMMMVVKFVLDAVFADSNLRWRSGEKTTSSTKRSKIINELASSSSNNNNSCSNVMGRRSDLVLTNKHGVNLCLVESKNGSSCYEEISQDSKSVRCTKSLYAYNSALSHQCLWSMNWNGYEGDMYYMRKHEGVDVVLAVEHLSIPTRACLIDSLKNTLVAFYKFKEQMLAYDRSITYSFTISEETDTRVYHSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NFJ7</accession>
    <name>A0A1C7NFJ7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Protein SGT1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">ECD</name>
        <name evidence="2" type="ORF">A0J61_04087</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000192">
        <property type="protein sequence ID" value="OBZ87865.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NFJ7"/>
    <dbReference type="FunCoup" id="A0A1C7NFJ7">
        <property type="interactions" value="841"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NFJ7"/>
    <dbReference type="InParanoid" id="A0A1C7NFJ7"/>
    <dbReference type="OrthoDB" id="27237at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010770">
        <property type="entry name" value="Ecd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13060:SF0">
        <property type="entry name" value="PROTEIN ECDYSONELESS HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13060">
        <property type="entry name" value="SGT1 PROTEIN HSGT1 SUPPRESSOR OF GCR2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07093">
        <property type="entry name" value="SGT1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="509"/>
            <end position="538"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="572"/>
            <end position="605"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="525"/>
            <end position="537"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="592"/>
            <end position="603"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ87865.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="648" mass="74273" checksum="B0BB6620FF307D5E" modified="2016-11-30" version="1">MSELNLEDIFKGSSSKEINYIQYAIYLPPKESDQATRSYLRDTLDMIHSLTQPIIDDYIWQKDRFQLSIAYAQDQDPAYPFLFGASRFGDCINDEWFIVYLLQQISKDVPEAVIALNDNDGDVILIEAALDLPHWLDPSNSQNRVYLYRGQVHIIPLPTSPADIMQLNTGRLRRERAIDQVRTQPSTLASSGIQQAIADRTGPYPLAARQEHHRSRILLPSKAAFTLLSQPQLITYAIEAFYLRDPIAMKACAAMATFSPSEGMVETTIRFTKTSYAQAVSQKFYAPKPFRLPSMKEKKKYHAAELGMKVACGLEMLYHNSLASHGHNEESMETYDFEADKKFAAYLAHLDQLGYFRDQKKGSQLYRQLYAQAKEQYLMYKKEESLSEKPYCVPLEDLDVDDEETFKQSLSLLSLPRQTMDTLLSQYSDEALEKLLDRYSNEPEDSDDWMNVDPQQLEELLMKRMGTMNQSMMADLQKDFSPTESRQLEEGVDLEKMMSSFENFVENSKSGIDGVEFPNDLREFSDDEDEDEDEEDGAIQFDMNEFMRILKGTKHLESEKDLTEVMDEMDQEISGHEKISNSFTKLSKKDTEEDEEDEDEDAPVDVQLNLVKNVLESFKSQQGLPGPVGNMLSQFGFVLPGDNEEEEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NFP7</accession>
    <name>A0A1C7NFP7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Response regulatory domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">A0J61_03999</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000186">
        <property type="protein sequence ID" value="OBZ87943.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NFP7"/>
    <dbReference type="InParanoid" id="A0A1C7NFP7"/>
    <dbReference type="OrthoDB" id="21225at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd17546">
        <property type="entry name" value="REC_hyHK_CKI1_RcsC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45339">
        <property type="entry name" value="HYBRID SIGNAL TRANSDUCTION HISTIDINE KINASE J"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45339:SF1">
        <property type="entry name" value="HYBRID SIGNAL TRANSDUCTION HISTIDINE KINASE J"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="CheY-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="1 3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0902">Two-component regulatory system</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="100"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="124"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="153"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="domain" description="Response regulatory" evidence="6">
        <location>
            <begin position="1060"/>
            <end position="1246"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="27"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="546"/>
            <end position="565"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="578"/>
            <end position="597"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="632"/>
            <end position="683"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="917"/>
            <end position="951"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="999"/>
            <end position="1058"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1151"/>
            <end position="1191"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1263"/>
            <end position="1291"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1321"/>
            <end position="1365"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="27"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="40"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="547"/>
            <end position="565"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="585"/>
            <end position="595"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="639"/>
            <end position="648"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="655"/>
            <end position="670"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="917"/>
            <end position="930"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="1004"/>
            <end position="1019"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="1020"/>
            <end position="1031"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="1032"/>
            <end position="1047"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="1152"/>
            <end position="1170"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="1171"/>
            <end position="1191"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="1279"/>
            <end position="1291"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="1339"/>
            <end position="1355"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="3">
        <location>
            <position position="1109"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OBZ87943.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="1391" mass="153469" checksum="D9D37B14713AA849" modified="2016-11-30" version="1">MTSQQNNNHSPPSAFLNATSALPTFSLPPNLNNRSIHNKQTQENKDDSDNKASSNRLTIADLTPDNLLRQTSEDNCIDIKLPDVTTSHLELSLLTREMKLLLLVATTCCLVSSCYLTMTSERSLLATASTGKWLLVMLWIVSDQHQPSLYSSYSIFLSVSAFCLWMFTMYGWSCVSIIRASQFGAVVSFVMVYRLSVIYRQLQAQLTEQQQQYHSKVQQVIDQAIEKHAVQRKSFLAIASQEMKDIASTIMATIEQFAPSSILSNTHELLSACSIAVPTTSISAINTMVKQTCHISSHFTLLIKLLQSSDHAPVQSYICREFDVGELIQSVGDALAGMSAKLGVHLIIYHMDDVLYYPNVMGDEDATRHALISLLKNMLEGCTPGACIEVGLSVAPIPDSDKHKVTFHITHTASPSIPPGLSAAPIPNTGLTVRLIHFIRGQMDMEDLNKNKTLVKLTLELSPGSNNEQRLLLIERQLSNVQFANEPTLEELNSFVTKLKGVRLILHAPEKSIFAKHLTSCLASWNTDISHLPVLGYSTVDEEGSVASDTTAHGTDSDTSVHSQQPIKTPLDIHALLSPSSRPINTANTSANTNSKIPSPAIAEEQIHSIPPAFILIDDDIMTFERKLKEFRDKPPVPSQQQQQQQTPTVPPVTPQLQSSQAQQTSSQQPSRRHRRTKSRSSLASDVILHGTVAVVFFSSLGNYKRVRDTIQWFSSIHVPGLPRVIVVPKPAGPRRFLTALHTAWRNAVVEPQFIPIATSPVSPFIGVTHLTPTAGTVPPEGLTPSAALTPHDATRFSPGTRRNRLHSPSGLHLESEKGNYFFDPLAARPNLTSSTNHTGSGMNHNAMLPPKLNTSPHLMAAKSNGLMGVATPISASASTAVGGLTTPKNLSSTPILGNNVNTANGKQVDLKRTFRSHSNNTFAPSTPSRRNLVDLARSPSSSGKQASPLLEDEKHLSMNDLATESLPPPIVNANHLPAFHGSSPHLEHIVSPKLDSQGAQIENTNPTTKVVTANTTGTSDASNDNTVNTKPKSKYNFKLSNRKRKEKSSQPEKQSPPITVLIVEDNMINQAILSTWMRKHKIKFSVASDGKEAVEKWKGGGFHLILMDIQLPVLDGIEATKMIRSIEKERKIGVLPATIDEVDEEAVLQAEKQKEEEEKIRQQEEEIKQQEAATKQESGSAKLSPSASSKTVSEKRVFQSPVIIVALTASSLESDRQAALAAGCNDFLTKPVSLEWLEKKIMEWGCMQALIDFEGWRKWKDKQNAPNNPFLKQPQPLQKRDSQDKEQQQRVQEELNRRVKEMFKDESKAIVLLGLNKKRDGRSAADNNRASNAKKSRNNYSSRRSASDSLLELSIPRQMEARERKRQLEQEAFMKLTQSSLSQDEDEDED</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NG12</accession>
    <name>A0A1C7NG12_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_03917</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000180">
        <property type="protein sequence ID" value="OBZ88032.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NG12"/>
    <dbReference type="InParanoid" id="A0A1C7NG12"/>
    <dbReference type="OrthoDB" id="64113at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="106"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="106"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="119"/>
            <end position="135"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ88032.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="135" mass="15982" checksum="865DBF7E4C706786" modified="2016-11-30" version="1">MEQRIQQFHDDTKTIPKPPTAKTVKQMNALKKFIFKNQDYRFSDKEKNKLFACIEAYFTVFDRSGLTDTMSAFPLIEDALKVPCFTTKQKSQLLKWYDEILAKQEGGEKQTDQKKNNEEENYDDFDWDAFAEEEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NG94</accession>
    <name>A0A1C7NG94_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_04189</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000199">
        <property type="protein sequence ID" value="OBZ87759.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NG94"/>
    <dbReference type="InParanoid" id="A0A1C7NG94"/>
    <dbReference type="OrthoDB" id="2281185at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="49"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="55"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ87759.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="93" mass="10406" checksum="A79CCB4DF429E1FD" modified="2016-11-30" version="1">MDPGYKLLQHIKTVPNLINEDPSITTPKNSTFMDLPWSDFSKLLADKKIQRRSSDTSVNSSASSSSDESPENFSLGNWDSMTGYQDAEHRPTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NGT0</accession>
    <name>A0A1C7NGT0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein C4G3.03</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">SPCC4G3.03</name>
        <name evidence="1" type="ORF">A0J61_03649</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000161">
        <property type="protein sequence ID" value="OBZ88307.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NGT0"/>
    <dbReference type="STRING" id="101091.A0A1C7NGT0"/>
    <dbReference type="InParanoid" id="A0A1C7NGT0"/>
    <dbReference type="OrthoDB" id="64353at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43991:SF9">
        <property type="entry name" value="DUF2415 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43991">
        <property type="entry name" value="WD REPEAT PROTEIN (AFU_ORTHOLOGUE AFUA_8G05640)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ88307.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="218" mass="24518" checksum="0156356FCE21FCBC" modified="2016-11-30" version="1">MTIIDTTCVSRSDILNTFVIPKPVVHDQKVTIHHWQLRDVLIPNDEQHKHELIVPTGQDIFRYNYKTGQKSYFLKDIGYPPTCMASGYGYWAAGGQKGDLTLKDTTSDYQVSITTAPGFTINNGLCFSQLNGEVRLLVSNNDASIRIYSVPDLDLIDTLDFRTAVNHTSVSPDGRKMITVGDDNRVQLFHVTSLGHYELVTTMAGKNDISFLFLMSYY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NGW4</accession>
    <name>A0A1C7NGW4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">p21-activated protein kinase-interacting protein 1-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">pak1ip1</name>
        <name evidence="5" type="ORF">A0J61_04160</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000197">
        <property type="protein sequence ID" value="OBZ87786.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NGW4"/>
    <dbReference type="FunCoup" id="A0A1C7NGW4">
        <property type="interactions" value="470"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NGW4"/>
    <dbReference type="InParanoid" id="A0A1C7NGW4"/>
    <dbReference type="OrthoDB" id="308449at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042254">
        <property type="term" value="P:ribosome biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051959">
        <property type="entry name" value="PAK1-Kinase_Regulator"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44675:SF1">
        <property type="entry name" value="P21-ACTIVATED PROTEIN KINASE-INTERACTING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44675">
        <property type="entry name" value="PAK1 INTERACTING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="1" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="2 4" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="78"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="119"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="159"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="241"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="285"/>
            <end position="320"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OBZ87786.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="359" mass="40507" checksum="B8F827F05991877A" modified="2016-11-30" version="1">MENKKRPRSSDDMTDNQAKKRQILEKVSQSTLLPTSALLEIEEDFRVIVGTYERLLFGLNANWLENEEKVKLEPVFIIPAHTACIRTVAVGGHFLASGSSDEIIRLYDVKKRKEYGSLGGHHSGDITDIQFHGKYMLSASDDHLINLWRTKDWEFLKTLKGHKAKVNAMAVHPTGKIALSVSADRTAIVWNLMTGRKASVNKLGREEPMSVLWNTAGDQYAILFDKSIQVYKVVDAKVALTISHRSRIHTMRYFKLEDKEYIVTGSEDKTIRIWDTTTGDCLKEIKGHAMRIKSTSVLETGNRKILISASSDGMVKCWDLAALMKDEEAEALGEYNTKCRITCITSHDGFSTEPTKQQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NHE8</accession>
    <name>A0A1C7NHE8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_03392</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000145">
        <property type="protein sequence ID" value="OBZ88552.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NHE8"/>
    <dbReference type="InParanoid" id="A0A1C7NHE8"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ88552.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="111" mass="12847" checksum="598946A357783438" modified="2016-11-30" version="1">MILLRTDEPAMDTPKQKQYSSHSRLMLKPLEVDSNGIVPGRKTQTLCLKLLFEESTTRAFRARHSRGVKSYYLLINNASIHTFKLIKFVTESNKHRCVCLLSYSFELNLID</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NHX2</accession>
    <name>A0A1C7NHX2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_03318</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000140">
        <property type="protein sequence ID" value="OBZ88635.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NHX2"/>
    <dbReference type="InParanoid" id="A0A1C7NHX2"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ88635.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="88" mass="9399" checksum="186925A4195C810A" modified="2016-11-30" version="1">MSVPNPVYNASPMYASPAMPIMTPGSPYGPSPYAPGMAAQTAYYPPMGAMQVGPGQPMVMPQQPYGIYTRQRRCCDCCYGDCNCCAGM</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NHZ9</accession>
    <name>A0A1C7NHZ9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">NodB homology domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_03334</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000141">
        <property type="protein sequence ID" value="OBZ88620.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NHZ9"/>
    <dbReference type="STRING" id="101091.A0A1C7NHZ9"/>
    <dbReference type="InParanoid" id="A0A1C7NHZ9"/>
    <dbReference type="OrthoDB" id="504708at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052740">
        <property type="entry name" value="CE4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45985">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45985:SF3">
        <property type="entry name" value="CHITIN DEACETYLASE-LIKE 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008889705" description="NodB homology domain-containing protein" evidence="1">
        <location>
            <begin position="20"/>
            <end position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ88620.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="95" mass="10297" checksum="5B52D0F3895116FE" modified="2016-11-30" version="1">MKLLTISLVLSLFVTESWAQSEGAIVRPGPPTSFSYSCDPNSCKIANNCACASKNPPNGLLPNETPQFVTVTFDDSIQAQLYQTAKKMLNVTQVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NI48</accession>
    <name>A0A1C7NI48_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">B box-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">A0J61_03227</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000135">
        <property type="protein sequence ID" value="OBZ88725.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NI48"/>
    <dbReference type="InParanoid" id="A0A1C7NI48"/>
    <dbReference type="OrthoDB" id="406045at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.640.40">
        <property type="entry name" value="Cytoplasmic polyadenylation element-binding protein, ZZ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038446">
        <property type="entry name" value="CEBP_ZZ_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018553">
        <property type="entry name" value="E2_Ub-conjug_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057668">
        <property type="entry name" value="E2_Ub-conjug_enz_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000315">
        <property type="entry name" value="Znf_B-box"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31560">
        <property type="entry name" value="UPF0652 PROTEIN C16A11.03C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31560:SF0">
        <property type="entry name" value="UPF0652 PROTEIN C22H10.08"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22586">
        <property type="entry name" value="ANCHR-like_BBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09418">
        <property type="entry name" value="DUF2009"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57845">
        <property type="entry name" value="B-box zinc-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50119">
        <property type="entry name" value="ZF_BBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="B box-type" evidence="3">
        <location>
            <begin position="40"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="79"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="87"/>
            <end position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OBZ88725.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="589" mass="67911" checksum="741D55930A9B523D" modified="2016-11-30" version="1">MPTDEKKRHQLENILSDNVSIMDTEDLSYEQPSLETEEQVREGFCVECKDQEADMFCTNCNEPFCEVCYGMIHRTGKRATHKSKPFNVRETKEENEGAEQEDHQVKVTEEKDPLPNKKAEINIGEIMEERAKYIPLRLEMAERKFLRMLEAALNVTNYTEKIDDPVSTGKAKRVVNQIKELCAILTGIVLGCDYKRGQELFADRSYEDNEEFFQTIFEIGRRYKIMNPEKMRSAYGKLMYLLSDSMIPEVKEMLGFDCVVPIKTVYSFLKERHGLSVLHEDIVLLATMEIIPDGKTRPQIQLEIKRKERSIEQLSRKYQSKFLSADEIRRCLYSIGDNNAYLRANRDPCEKMIRYLEKYFSPKQEDNGDYSLSIASGSQGHRLSHDHETQYIYVNQTLQLWRAILNDMFKLWTLADQDMLSTSNPYQLAQTGQGLHRVQPCPAVSREMHRTLFKAQKKAGTWIGSSVIHLGDKNVPNALMFIDKYNQVARILSPICITIDRLEELAKDKGICKFIENKFGGLDLCRKTILTDFFRFAFDGSGADNFYDAGSCIDGRLTSAWNWCSQIEKKPYFPVFLLTGFAGFDGGGW</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NIF5</accession>
    <name>A0A1C7NIF5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_03063</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000125">
        <property type="protein sequence ID" value="OBZ88892.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NIF5"/>
    <dbReference type="InParanoid" id="A0A1C7NIF5"/>
    <dbReference type="OrthoDB" id="2267458at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ88892.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="151" mass="17387" checksum="3AB3413A85A573CB" modified="2016-11-30" version="1">MNSTTSYPSFHPTYTQTKSSKDIDASVYHLLSLYLTKDALTNTTTLLKRPTKPSSKTYLHRIFQPQRSWLGEETKEECDTVLERNTIENAFIQVTQTTNTTLKKKKKRAKAVSFSNTVTVVLSEDNVSTTHLNREENEEEECFVDALEYIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NIM9</accession>
    <name>A0A1C7NIM9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_03101</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000128">
        <property type="protein sequence ID" value="OBZ88850.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NIM9"/>
    <dbReference type="InParanoid" id="A0A1C7NIM9"/>
    <dbReference type="OrthoDB" id="2300010at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ88850.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="71" mass="8622" checksum="8692A0249F8102A8" modified="2016-11-30" version="1">MSECRFSHTDKPHLRAHLLQLEELQQQYFRDHPKEDQEEVRYFEAGHFGRSLVSRFSENLVETDLKERENC</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NJ57</accession>
    <name>A0A1C7NJ57_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">4-hydroxybenzoate polyprenyltransferase, mitochondrial</fullName>
            <shortName evidence="10">4-HB polyprenyltransferase</shortName>
            <ecNumber evidence="10">2.5.1.39</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Para-hydroxybenzoate--polyprenyltransferase</fullName>
            <shortName evidence="10">PHB:PPT</shortName>
            <shortName evidence="10">PHB:polyprenyltransferase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="primary">Coq2</name>
        <name evidence="11" type="ORF">A0J61_02797</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9 10">Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8 10">
            <text>an all-trans-polyprenyl diphosphate + 4-hydroxybenzoate = a 4-hydroxy-3-(all-trans-polyprenyl)benzoate + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:44504"/>
            <dbReference type="Rhea" id="RHEA-COMP:9514"/>
            <dbReference type="Rhea" id="RHEA-COMP:9564"/>
            <dbReference type="ChEBI" id="CHEBI:17879"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58914"/>
            <dbReference type="ChEBI" id="CHEBI:78396"/>
            <dbReference type="EC" id="2.5.1.39"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 10">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="10">Cofactor biosynthesis; ubiquinone biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 10">Mitochondrion inner membrane</location>
            <topology evidence="2 10">Multi-pass membrane protein</topology>
            <orientation evidence="2 10">Matrix side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the UbiA prenyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.39" evidence="10"/>
    <dbReference type="EMBL" id="LUGH01000110">
        <property type="protein sequence ID" value="OBZ89167.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NJ57"/>
    <dbReference type="FunCoup" id="A0A1C7NJ57">
        <property type="interactions" value="226"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NJ57"/>
    <dbReference type="InParanoid" id="A0A1C7NJ57"/>
    <dbReference type="OrthoDB" id="18170at2759"/>
    <dbReference type="UniPathway" id="UPA00232"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008412">
        <property type="term" value="F:4-hydroxybenzoate polyprenyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008299">
        <property type="term" value="P:isoprenoid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006744">
        <property type="term" value="P:ubiquinone biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd13959">
        <property type="entry name" value="PT_UbiA_COQ2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.120.1780:FF:000001">
        <property type="entry name" value="4-hydroxybenzoate octaprenyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.357.140:FF:000003">
        <property type="entry name" value="4-hydroxybenzoate polyprenyltransferase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.357.140">
        <property type="entry name" value="UbiA prenyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1780">
        <property type="entry name" value="UbiA prenyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01635">
        <property type="entry name" value="UbiA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006370">
        <property type="entry name" value="HB_polyprenyltransferase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039653">
        <property type="entry name" value="Prenyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000537">
        <property type="entry name" value="UbiA_prenyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030470">
        <property type="entry name" value="UbiA_prenylTrfase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044878">
        <property type="entry name" value="UbiA_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01474">
        <property type="entry name" value="ubiA_proteo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11048:SF28">
        <property type="entry name" value="4-HYDROXYBENZOATE POLYPRENYLTRANSFERASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11048">
        <property type="entry name" value="PRENYLTRANSFERASES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01040">
        <property type="entry name" value="UbiA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00943">
        <property type="entry name" value="UBIA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0414">Isoprene biosynthesis</keyword>
    <keyword evidence="7 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="10" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10 11" id="KW-0808">Transferase</keyword>
    <keyword evidence="5 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="10" id="KW-0831">Ubiquinone biosynthesis</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004292"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00052313"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00058997"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="OBZ89167.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="363" mass="40157" checksum="0A90EE54FAD6FCA9" modified="2016-11-30" version="1">MSFRLIVPSLLKQPIRSIQIRPFIRPLVRPHVLKATSHHFIVQKQWTSTITDTEKLKENRIVYNNWLDHLPTKIAPYAALTRIDKPIGTWLLFWPCAWSISMASYHMDGSIMDAAKMIGLFGAGALIMRGAGCTINDLWDRDIDNKVERTKVRPITSGVISPKQAIGFLGLQLSAGLAILTQLNMYSILLGASSLSLVVTYPLMKRVTYWPQTVLGLAFNWGALLGWSAMTGSLDLSVAGPLYAGGVCWTLVYDTIYAHQDKKDDIKVGVKSTALRFGEKTPEWLAGFSSVFVGMTALSGYMNDQGLPFYAISVLGTAAHLAWQLKTVDYNSPTSCWSRFKSNTWTGAILWSGILADAAYTSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NJD5</accession>
    <name>A0A1C7NJD5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Calcium influx-promoting protein ehs1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">ehs1</name>
        <name evidence="5" type="ORF">A0J61_02764</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000109">
        <property type="protein sequence ID" value="OBZ89185.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NJD5"/>
    <dbReference type="FunCoup" id="A0A1C7NJD5">
        <property type="interactions" value="102"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NJD5"/>
    <dbReference type="InParanoid" id="A0A1C7NJD5"/>
    <dbReference type="OrthoDB" id="5405745at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005262">
        <property type="term" value="F:calcium channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098703">
        <property type="term" value="P:calcium ion import across plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.2000.10">
        <property type="entry name" value="Frizzled cysteine-rich domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020067">
        <property type="entry name" value="Frizzled_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036790">
        <property type="entry name" value="Frizzled_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024338">
        <property type="entry name" value="MID1/Yam8"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39142:SF1">
        <property type="entry name" value="AEL197CP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39142">
        <property type="entry name" value="MID1P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12929">
        <property type="entry name" value="Mid1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50038">
        <property type="entry name" value="FZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008889733" evidence="3">
        <location>
            <begin position="20"/>
            <end position="506"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="484"/>
            <end position="503"/>
        </location>
    </feature>
    <feature type="domain" description="FZ" evidence="4">
        <location>
            <begin position="273"/>
            <end position="496"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50038"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OBZ89185.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="506" mass="55659" checksum="4CFE11724042A8F1" modified="2016-11-30" version="1">MILQYTILFIAVLFQYACTQSTTPINNNQILSSSVSVNTYQYFYFTIPSTTQFFRKRDYPPIHLTVSTCSQPQSSSSQSIPPVSIYLSTSSANTLPGPGNGITVDNSLNGLTSWTSDGTSSQLWIAVGGPSLENASGNWTFEIGVSINNPLHVVYQNEDRADNSSIPYFILDDTDRNNALFLSSPFSGSAPNASILIASNLPSELTYSLCAAKLNAATNYSVNTTTTMRGSTNSSKFQFMVSNLSQDTIYTAYMTQTVNGVTGMTTPIRMSTKSDANCRIIYDLPFCDQVAYSVPVNPSTFGTENIWDVANQYDAQALEKFEPFSVALSQFNCETTQYSLVRNCTDCYRDYKTWLCSVTIPRCTDSSSTADLTQGTDDVVAAPALRDTSINASRNPWIDETMTPGEWTELLPCIDLCYHVVQSCPPFLSFRCPTGDLRSVQYGYWQQGLGTANGTTYRFDINNPTCNRMGVSPQQLVISTALKMAPTMTIVICTSLSLLFIIYDVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NJZ0</accession>
    <name>A0A1C7NJZ0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="11">E3 ubiquitin-protein ligase MARCH5</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">March5_1</name>
        <name evidence="11" type="ORF">A0J61_02454</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000093">
        <property type="protein sequence ID" value="OBZ89483.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NJZ0"/>
    <dbReference type="FunCoup" id="A0A1C7NJZ0">
        <property type="interactions" value="12"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NJZ0"/>
    <dbReference type="InParanoid" id="A0A1C7NJZ0"/>
    <dbReference type="OrthoDB" id="5817083at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011016">
        <property type="entry name" value="Znf_RING-CH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46283">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE MARCH5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12906">
        <property type="entry name" value="RINGv"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00744">
        <property type="entry name" value="RINGv"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51292">
        <property type="entry name" value="ZF_RING_CH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4" id="KW-0863">Zinc-finger</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="120"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="160"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="186"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="208"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="280"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="319"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="domain" description="RING-CH-type" evidence="10">
        <location>
            <begin position="32"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="10"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51292"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="OBZ89483.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="366" mass="41303" checksum="AF30EAC5A15A32C7" modified="2016-11-30" version="1">MSHFRGYLAQSETDLHQNSSDSSTILAPRQPTRTVDDRRCWICFGDSSDSQGQWIKPCQCSLEAHQSCLLDWIAENQKATPNKTVNCPQCATPYQLAQTNSISLALMTIVDSLVRTSTPYITVLGIGCSLLITCTTYGAFSVMTLFGPRDGDRLIGHPASWTYKTWIGLPAIPFMLISSRTRYGDLILPSASFLILGAAGTTPNHLRFTWPLSPAFTVGIMPWVRLFYKNMFLQVQKHVTKKLAIQPVERVNRSRNTNNVDISDREHHLELDIIQGRGSVGISLLGTLLMPVISSAMGSLLNRLYWVRENFPQPFQRNVLGGCVFVVVKDLGILLYKYERIRQYRSRRVKSYEEVIATRKSHQQTQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NK17</accession>
    <name>A0A1C7NK17_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_02563</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000098">
        <property type="protein sequence ID" value="OBZ89385.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NK17"/>
    <dbReference type="STRING" id="101091.A0A1C7NK17"/>
    <dbReference type="InParanoid" id="A0A1C7NK17"/>
    <dbReference type="OrthoDB" id="2358153at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="149"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="160"/>
            <end position="180"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ89385.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="471" mass="53111" checksum="3788D592CD4A9DE8" modified="2016-11-30" version="1">MSENNLFQFARVIADLPIQNTASHERQGHHLSRENHHHLHNYNSRYLNIRKNACIVCSVCFTCSKYYGIDCACQEVQPRRGKNLPEGGLDSRAKKLHREDTDDYEFSIRWINENAHAMYKDESGQVVGLRDLIEVSLCKAHSSTLYRAKKRHERTKDFSMPPPAPLGSLPPPSSNAPPSPADSNEMHYNPYPMNQSIVSSGGLAAKVREISSLQHPQQMVRMHDTPDFSRMTHSTSNKRKRIYKHAVQKSPPKIEANTIRPHSSISTPLYGTPRQDNMFMQPHYPFTPSTSANHNPHIQEFQPAHDNIQTVDSFPSQLPPLHPSRGIANMASPPQQQQQLVYPLESPRPTATKSMINTSVPMPEPMDISPLMVETVSLRPLIPSSASSSASDNYYFRNLAITDTFTFRDLLAEIDMTGSPPPGKRIVISDADKFYPLDQAIRSVIRRPTSTHLELCLGLTDKPSIDWSTYS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NK34</accession>
    <name>A0A1C7NK34_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">BAG domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_02536</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000097">
        <property type="protein sequence ID" value="OBZ89405.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NK34"/>
    <dbReference type="STRING" id="101091.A0A1C7NK34"/>
    <dbReference type="InParanoid" id="A0A1C7NK34"/>
    <dbReference type="OrthoDB" id="417450at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051087">
        <property type="term" value="F:protein-folding chaperone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.120">
        <property type="entry name" value="BAG domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036533">
        <property type="entry name" value="BAG_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003103">
        <property type="entry name" value="BAG_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02179">
        <property type="entry name" value="BAG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00264">
        <property type="entry name" value="BAG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63491">
        <property type="entry name" value="BAG domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51035">
        <property type="entry name" value="BAG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BAG" evidence="1">
        <location>
            <begin position="143"/>
            <end position="199"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ89405.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="211" mass="24046" checksum="7AFA64178EEC3063" modified="2016-11-30" version="1">MSVRLNISWRGKKFFIEFGSLSELNNTTVNQLKVSCQRVVGIDAASFDLFAFGGELNLFVRPRMNNLELPLYTYELQPSCNVVLVENKNVLQELTGTKPQKDEGYLLTQLDTIQVKLRQEIVPQIEQYEQQAKALSHKCSAKKKKQHTYTAAYLSEQLMHILFDLDSVICGPEAATAKQTRKQIVKQAQTLLDKTDEIKSIVNHISLEQQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NKA0</accession>
    <name>A0A1C7NKA0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Putative helicase mug81</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">mug81</name>
        <name evidence="10" type="ORF">A0J61_02396</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000089">
        <property type="protein sequence ID" value="OBZ89563.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="FunCoup" id="A0A1C7NKA0">
        <property type="interactions" value="401"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NKA0"/>
    <dbReference type="InParanoid" id="A0A1C7NKA0"/>
    <dbReference type="OrthoDB" id="5575at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022626">
        <property type="term" value="C:cytosolic ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0180022">
        <property type="term" value="C:RQC-trigger complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002181">
        <property type="term" value="P:cytoplasmic translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006417">
        <property type="term" value="P:regulation of translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072344">
        <property type="term" value="P:rescue of stalled ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990116">
        <property type="term" value="P:ribosome-associated ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd18020">
        <property type="entry name" value="DEXHc_ASCC3_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18022">
        <property type="entry name" value="DEXHc_ASCC3_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18795">
        <property type="entry name" value="SF2_C_Ski2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000198">
        <property type="entry name" value="Activating signal cointegrator 1 complex subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.3380.10:FF:000002">
        <property type="entry name" value="Activating signal cointegrator 1 complex subunit 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.150:FF:000113">
        <property type="entry name" value="activating signal cointegrator 1 complex subunit 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000231">
        <property type="entry name" value="Activating signal cointegrator 1 complex subunit 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.150:FF:000004">
        <property type="entry name" value="RNA helicase, activating signal cointegrator 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000102">
        <property type="entry name" value="RNA helicase, activating signal cointegrator 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.10:FF:000012">
        <property type="entry name" value="U5 small nuclear ribonucleoprotein helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.10:FF:000024">
        <property type="entry name" value="U5 small nuclear ribonucleoprotein helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.150.20:FF:000004">
        <property type="entry name" value="U5 small nuclear ribonucleoprotein helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.3380.10:FF:000001">
        <property type="entry name" value="U5 small nuclear ribonucleoprotein helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000062">
        <property type="entry name" value="U5 small nuclear ribonucleoprotein helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.20">
        <property type="entry name" value="5' to 3' exonuclease, C-terminal subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.150">
        <property type="entry name" value="C2 domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3380.10">
        <property type="entry name" value="Sec63 N-terminal domain-like domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035892">
        <property type="entry name" value="C2_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050474">
        <property type="entry name" value="Hel308_SKI2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004179">
        <property type="entry name" value="Sec63-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057842">
        <property type="entry name" value="WH_MER3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47961:SF13">
        <property type="entry name" value="ACTIVATING SIGNAL COINTEGRATOR 1 COMPLEX SUBUNIT 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47961">
        <property type="entry name" value="DNA POLYMERASE THETA, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G05260)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02889">
        <property type="entry name" value="Sec63"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23445">
        <property type="entry name" value="WHD_SNRNP200"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF039073">
        <property type="entry name" value="BRR2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00973">
        <property type="entry name" value="Sec63"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="E set domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF158702">
        <property type="entry name" value="Sec63 N-terminal domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 10" id="KW-0347">Helicase</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="8">
        <location>
            <begin position="122"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="9">
        <location>
            <begin position="351"/>
            <end position="549"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="8">
        <location>
            <begin position="983"/>
            <end position="1158"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="9">
        <location>
            <begin position="1190"/>
            <end position="1399"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OBZ89563.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="1802" mass="204708" checksum="75F5EBA20296AF90" modified="2016-11-30" version="1">MSILGFDGDDLRQAREDALLNASQAPLFSSNYKTKSQPTYPHVYQANQAGGTLSLFGTRFALPAGTVREDYNDYEETIIPVPKIAPVRTGERRIPIAELDNLASNAFKAYETLNRVQSIVYPVAYETNENMLVCAPTGAGKTDVAMLTVLRCLSQHCSPPPHTGTTEIDFTIAKNDFKIVYVAPMKALAAEVVEKMSKRLKFLGVSVRELTGDMQLTKAEISATQFIVTTPEKWDVITRKGTGDVELTQKVKLLIIDEVHLLHEDRGAVIESIIARTLRQVESSQSLIRIVGLSATLPNYVDVAAFLRVNPYQGLFYFDNGFRPVPLEQHFLGIKGKPNTVPSNERMNRACFDKVSELVRDGHQVMVFVHARKETVKTAQMLREEVANEMMGSYFDCSDSPKYSQFKRDVSKSRNKELKELFQYGFGIHHAGMLRSDRNLTEKMFQEGALKVLCCTATLAWGVNLPAYAVVIKGTQVYDSTKGSFVDLSILDVLQIFGRAGRPQYETHGVGYILTTHDRLSHYISAITQQHPIESKFIENIVDNLNAEISLGTVTNVDEAVTWLSYTYLYVRMKKNPMVYGMDHSEAVNDPLLGRKRHEIITMAARKLANCQMIIFDENTGYLLPKDLGRIASNFYIKHTSIEIFNTMMKPRMTEADVLSMMSMSSEFDQIKSRENEHQELKNLLDNACACDIRGGTEDTHGKVNILLQSYVSNAYIEDFALVSDCAYVAQNSGRIARALFEIALNRNWGPTASVLLQINKAVEKRMWTFQHPLRQMPLPQDIINKIENRTHEVSIEEMRDMDPTELGDLVRHARMGMTISKCVDEFPMLLLDARIAPITRNVLHIELTITPDFVWNDRLHGSVEPWYIWAEDSENVEIYYSEYFLLYKKQFGEPIKIVFTVPLVEPLPSQIYVRAVSDRWLGAETVLPISFQHLILPQLYPPHTDLLDLQPLPITALKNEVLEEICAKRFTHFNPVQTQIFHTLYNTDCNSLVGAPTGSGKTVAAELVMWAAFRDRPGSKVVYIAPMKALVKERVADWNKRLTGPMKKKLVELTGDVTPDLKTIESADIIITTPEKWDGISRSWQKRSYVRNVSCVIIDEIHLLGGDRGPILEVIVSRMNYIGSQLDQKVRIVGLSTALANAIDLANWLGIDKVGLFNFRHSVRPVPLEIYIDGFPGKHYCPRMATMNKPTYAAIKTHSPTQPVIVFVSSRRQTRLTAQDLIAYCGMEDNPRQWLHMDDNELEMLLSSIHDDSLRMSLAFGIGLHHAGLKESDRKVVEELFLNMKIQILIATSTLAWGVNLPAHLVVIKGTEFYNYKERRYVDFPITDVLQMMGRAGRPQFDNTGISRVFVQDSKKNFFKKFLHEPFPVESSLHKFLDDHINAEIVGGTIKTKQDALDYLTWTYFYRRLQQNPTYYGLDDMTQKGIDTYLSNTINEVAARLEKAGCVEVVDDFELVPLISARIASYYYLHPHTVRHFHDTLDEKSQIDDILTTLGNVPEYEELPARCQEDLLNQEIEKFIPYDVKGTANYISPHVKAYVLVQAHISRLQLPSSDYITDQITVLDSAIRFCQAMIDVVADNGYLNTCLTIMNVLQCIKQARWHDQSNLLTLPHIEPKMLHHIRHRGKTIKSVADLLRLPASQVKSIFSSVRDLDEEKIIEIQRVIDRMPCMNVKAEIDTQKTYLIPDTEYKISIQLNRIPHGSEKKMHDGRVYTPLFPKPQYESWWIVLGNPATDELLALKRISMRNGPNETLSNKASTSISFETPEHLGKHSYTLQLISDGYLGLDRKVDINFETRMDLDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NKG9</accession>
    <name>A0A1C7NKG9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Ribonuclease P protein subunit p21</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">Rpp21</name>
        <name evidence="5" type="ORF">A0J61_02644</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the eukaryotic/archaeal RNase P protein component 4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000102">
        <property type="protein sequence ID" value="OBZ89299.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NKG9"/>
    <dbReference type="FunCoup" id="A0A1C7NKG9">
        <property type="interactions" value="2"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NKG9"/>
    <dbReference type="InParanoid" id="A0A1C7NKG9"/>
    <dbReference type="OrthoDB" id="128536at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005655">
        <property type="term" value="C:nucleolar ribonuclease P complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008033">
        <property type="term" value="P:tRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.20.50.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007175">
        <property type="entry name" value="Rpr2/Snm1/Rpp21"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14742:SF0">
        <property type="entry name" value="RIBONUCLEASE P PROTEIN SUBUNIT P21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14742">
        <property type="entry name" value="RIBONUCLEASE P SUBUNIT P21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04032">
        <property type="entry name" value="Rpr2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0819">tRNA processing</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00038402"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OBZ89299.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="152" mass="17504" checksum="5ABF9A5F55C17B25" modified="2016-11-30" version="1">MAKKDKKTGVNPKNAQIFERLSYLHQASMLMSTIEYPTTTSDTPKEDTHVKHWQGDPPGRLHSTSRYFNHNMKQITARLVLRLDPSIKRTVCKRCETSLLPFITSKSRIHSKPVPSVVQTCTVCKAKRRYTSQNPDHVLFNEKAVVRPEEEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NLG9</accession>
    <name>A0A1C7NLG9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">FYVE-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">A0J61_01921</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000067">
        <property type="protein sequence ID" value="OBZ90021.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NLG9"/>
    <dbReference type="InParanoid" id="A0A1C7NLG9"/>
    <dbReference type="OrthoDB" id="2289620at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033565">
        <property type="term" value="C:ESCRT-0 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032266">
        <property type="term" value="F:phosphatidylinositol-3-phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043130">
        <property type="term" value="F:ubiquitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006623">
        <property type="term" value="P:protein targeting to vacuole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043328">
        <property type="term" value="P:protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd15760">
        <property type="entry name" value="FYVE_scVPS27p_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000306">
        <property type="entry name" value="Znf_FYVE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017455">
        <property type="entry name" value="Znf_FYVE-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47794">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47794:SF1">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01363">
        <property type="entry name" value="FYVE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00064">
        <property type="entry name" value="FYVE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50178">
        <property type="entry name" value="ZF_FYVE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="FYVE-type" evidence="6">
        <location>
            <begin position="592"/>
            <end position="645"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="19"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="106"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="180"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="221"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="37"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="114"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="221"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="232"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="276"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="291"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="311"/>
            <end position="328"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50178"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OBZ90021.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="653" mass="74232" checksum="2D22C8322AF2E3D6" modified="2016-11-30" version="1">MLQELQPVNLLARTNELSFPTKYSDPQRLDVGRKTTGRQQSITRGTASSNAKSVRINSAFNEPTARRKSLIKARIQSLASQVADKPAIQRKPSLIAVKHETIKLSTRPANNDHSTTNNSNLTSLNKQQPFQRRLSRKSSAISLAREQLTAQDKEDFVHPFEAPKAESPKVLADAVVNRTQQSPMLSQSSSEHTHHHYHSGDEHLPRYMRRPICAACNRNVKVTSSSETNNMRKSXSAVTASSTKSSFSSRNSKHMMHRSSNDNTNNKPNLALNKVSPGSTSSDYSRPSSMNNRSTSIGSISSASSHNSSIDQDTVSESQIVLRSKSPSSPIPTRRRKVVHRRKNINIKSHSNNALAKLSLDKWMKLLTQQQSALSALSGENSMILEGFDQMKIELNNANRDQHEAILLEIQTQVLQKFAFSLIEQQQQLFQYQKQQLLNYQLQEEQKTQTQIQKHMQLKDDSVQMIKSLDWLTKLEYDAVLLKWSMIQWTGNTIGIGEIEEQEFDMFGYPQSVVVSGVCVTVEPALLSKDLQKFLKPSDGQRKAICHKYKIQLTKDDRLFKFQLMKKEDWTKDKDVNQCEFSIRTDHKTNKCSREFGFFERRHHCRSCGHVFCQAHSANNLPLFVDNGQRGEWARVCDICFYRTIDPNSISRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NLK8</accession>
    <name>A0A1C7NLK8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Guanine nucleotide-binding protein subunit beta-2-like 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">gnb2l1</name>
        <name evidence="7" type="ORF">A0J61_01953</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the WD repeat G protein beta family. Ribosomal protein RACK1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000068">
        <property type="protein sequence ID" value="OBZ90013.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NLK8"/>
    <dbReference type="STRING" id="101091.A0A1C7NLK8"/>
    <dbReference type="InParanoid" id="A0A1C7NLK8"/>
    <dbReference type="OrthoDB" id="7875889at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043022">
        <property type="term" value="F:ribosome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045182">
        <property type="term" value="F:translation regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.10:FF:000018">
        <property type="entry name" value="Receptor for activated C kinase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045223">
        <property type="entry name" value="RACK1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19868">
        <property type="entry name" value="RECEPTOR FOR ACTIVATED PROTEIN KINASE C RACK1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="2 6" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="51"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="93"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="136"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="180"/>
            <end position="221"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007253"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OBZ90013.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="354" mass="39478" checksum="4781A49533754B99" modified="2016-11-30" version="1">MNNFALRGTLEVTSIVTSPNAPDMVVSASREITHDCPYRDEINYGVPRKALVGHNHIIQDLALSSDGQFVLSASWDHTLRLWDLATGKTTRRFVGHNKDVLSVSFSADNRQIVSGSRDKSIKLWNTLGECKYNISEDSHSDWVSCVRFSPNPAVPLIVSGGWDKLIKVWDLTKMKLRTNFIGHNGYVNTVAISPDASLCASAGKDGQVMLWDLSESKHLFSFEAGKEVNSLTFCPNHYWLCAAVGSSIKIWNLEDKSVVEVLTPEFNTTAKQADPLCLTLAWSDDGSALYAGYSDNLIRVYQVVRTLLYKSAAHHFLLKVESKHQNSHCIGHTNASDWGQKTSQNDEELKTFQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NM80</accession>
    <name>A0A1C7NM80_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">RNA-binding protein rnc1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">rnc1</name>
        <name evidence="5" type="ORF">A0J61_01672</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000056">
        <property type="protein sequence ID" value="OBZ90263.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NM80"/>
    <dbReference type="FunCoup" id="A0A1C7NM80">
        <property type="interactions" value="701"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NM80"/>
    <dbReference type="InParanoid" id="A0A1C7NM80"/>
    <dbReference type="OrthoDB" id="1937934at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035925">
        <property type="term" value="F:mRNA 3'-UTR AU-rich region binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070935">
        <property type="term" value="P:3'-UTR-mediated mRNA stabilization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:1903138">
        <property type="term" value="P:negative regulation of cell integrity MAPK cascade"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:1903753">
        <property type="term" value="P:negative regulation of p38MAPK cascade"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd22455">
        <property type="entry name" value="KH-I_Rnc1_rpt1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd22457">
        <property type="entry name" value="KH-I_Rnc1_rpt3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1370.10">
        <property type="entry name" value="K Homology domain, type 1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004087">
        <property type="entry name" value="KH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004088">
        <property type="entry name" value="KH_dom_type_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036612">
        <property type="entry name" value="KH_dom_type_1_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049786">
        <property type="entry name" value="Rnc1_KH-I_3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10288">
        <property type="entry name" value="KH DOMAIN CONTAINING RNA BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00013">
        <property type="entry name" value="KH_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00322">
        <property type="entry name" value="KH"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54791">
        <property type="entry name" value="Eukaryotic type KH-domain (KH-domain type I)"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50084">
        <property type="entry name" value="KH_TYPE_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="K Homology" evidence="4">
        <location>
            <begin position="21"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="domain" description="K Homology" evidence="4">
        <location>
            <begin position="112"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="domain" description="K Homology" evidence="4">
        <location>
            <begin position="234"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="211"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="213"/>
            <end position="224"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00322"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OBZ90263.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="325" mass="35559" checksum="CAFEA7B856A454C0" modified="2016-11-30" version="1">MSSAPSEQYDVETMSNQTQEEPLTLRALVSTKEAGVIIGKGGKNVAELREVTGVKAGVSKVVQGVHDRVLTVSGTLEGVAKAYSLIARTIIENSVQTQQTDGQEQNNHTDTAIATIRLLISHNLMGTVIGRQGAKIKYIQDLSGVRMTASKTLLPQSTERVVEVRGNVQSIEQAMSEIGTCLIEDKDRAYGTILYNPTKAAVNVQNNNFMPPRQHHQQQHHHHPSNVNNTSMEDIRTQHISIPSDMVGCIIGKGGQKISEIRKLSGSHISIAKFPHDDSGERMFTIQGTMGSNEKALFLLYGQLEAEKERRLRGVASMQPTSLEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NMH7</accession>
    <name>A0A1C7NMH7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Nucleoplasmin-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_01858</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000064">
        <property type="protein sequence ID" value="OBZ90079.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NMH7"/>
    <dbReference type="STRING" id="101091.A0A1C7NMH7"/>
    <dbReference type="InParanoid" id="A0A1C7NMH7"/>
    <dbReference type="OrthoDB" id="2265977at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.340">
        <property type="entry name" value="Nucleoplasmin core domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041232">
        <property type="entry name" value="NPL"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17800">
        <property type="entry name" value="NPL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nucleoplasmin-like" evidence="2">
        <location>
            <begin position="7"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="123"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="124"/>
            <end position="140"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF17800"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ90079.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="234" mass="26374" checksum="EDC0BC03C9D0C07E" modified="2016-11-30" version="1">MDNIFWEPGETCPVRIDGILRIQQACLPDNPKEGKTVLKVLVNGTNFVLCTLTKNRVESQKLSHIFTPKDQAKLSVEGPNGVDVTGYFDFMPVSEEDEEEEEEETVTGQPTYMNYLSDLLGPDLADDDDDDYEDEMDPSQDDYGTLAFRDPTDNDLLGGFELRHFNLVPNAPGFDRVDLRAEEQDIEETLLNDNIAKGLVNALLNSGDDMQIAKGKELARKLKKQCKQRRKKSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NMI2</accession>
    <name>A0A1C7NMI2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Eukaryotic translation initiation factor 1A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">tif11</name>
        <name evidence="5" type="ORF">A0J61_01650</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the eIF-1A family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000055">
        <property type="protein sequence ID" value="OBZ90285.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NMI2"/>
    <dbReference type="FunCoup" id="A0A1C7NMI2">
        <property type="interactions" value="688"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NMI2"/>
    <dbReference type="InParanoid" id="A0A1C7NMI2"/>
    <dbReference type="OrthoDB" id="274995at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd05793">
        <property type="entry name" value="S1_IF1A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00216">
        <property type="entry name" value="aIF_1A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006196">
        <property type="entry name" value="RNA-binding_domain_S1_IF1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001253">
        <property type="entry name" value="TIF_eIF-1A"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00523">
        <property type="entry name" value="eIF-1A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21668">
        <property type="entry name" value="EIF-1A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01176">
        <property type="entry name" value="eIF-1a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00652">
        <property type="entry name" value="eIF1a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50832">
        <property type="entry name" value="S1_IF1_TYPE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 5" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="1" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="S1-like" evidence="4">
        <location>
            <begin position="22"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="16"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU004364"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OBZ90285.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="139" mass="15943" checksum="00C2CBDB5BF8B892" modified="2016-11-30" version="1">MVKNKGKGGKSRRRGKNDTENDKRELVFKEEGQEYAQVTKMLGNGRVEAQCFDGVKRLALIRGKLRKKVWINQGDIVLLSLRDFQDEKADVIQRYNPDEARQLKSYGELPDTAKINETDNAFGGEEDDDVEFDFDIDDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NMI6</accession>
    <name>A0A1C7NMI6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">MULE transposase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_01618</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000053">
        <property type="protein sequence ID" value="OBZ90332.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NMI6"/>
    <dbReference type="InParanoid" id="A0A1C7NMI6"/>
    <dbReference type="OrthoDB" id="2276242at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ90332.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="140" mass="16076" checksum="44E5E7A7E0301F9B" modified="2016-11-30" version="1">MRKISFGLEQNSSARKVQNTISKDSPYNKSTKYDVKNMKNVYNQKTREASQRASTEQANVLIQQMESNGYMAFYDFNQTMFLKSIFFANKPMTERAKQFPEAIVIDANCKTDNLFMPSIDIYGVANIDQKSFKSFTVAFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NN25</accession>
    <name>A0A1C7NN25_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Hybrid signal transduction histidine kinase J</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">dhkJ_0</name>
        <name evidence="7" type="ORF">A0J61_02087</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000074">
        <property type="protein sequence ID" value="OBZ89876.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NN25"/>
    <dbReference type="STRING" id="101091.A0A1C7NN25"/>
    <dbReference type="InParanoid" id="A0A1C7NN25"/>
    <dbReference type="OrthoDB" id="10266508at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd16922">
        <property type="entry name" value="HATPase_EvgS-ArcB-TorS-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd17546">
        <property type="entry name" value="REC_hyHK_CKI1_RcsC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="entry name" value="Histidine kinase-like ATPase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45339">
        <property type="entry name" value="HYBRID SIGNAL TRANSDUCTION HISTIDINE KINASE J"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45339:SF1">
        <property type="entry name" value="HYBRID SIGNAL TRANSDUCTION HISTIDINE KINASE J"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="CheY-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="Homodimeric domain of signal transducing histidine kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0418">Kinase</keyword>
    <keyword evidence="1 3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <keyword evidence="2" id="KW-0902">Two-component regulatory system</keyword>
    <feature type="domain" description="Histidine kinase" evidence="5">
        <location>
            <begin position="229"/>
            <end position="554"/>
        </location>
    </feature>
    <feature type="domain" description="Response regulatory" evidence="6">
        <location>
            <begin position="777"/>
            <end position="919"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="557"/>
            <end position="590"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="679"/>
            <end position="711"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="719"/>
            <end position="738"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="844"/>
            <end position="868"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="948"/>
            <end position="979"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="565"/>
            <end position="590"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="679"/>
            <end position="688"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="721"/>
            <end position="734"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="851"/>
            <end position="867"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="3">
        <location>
            <position position="827"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OBZ89876.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="979" mass="109446" checksum="BDE656D0B5862EE5" modified="2016-11-30" version="1">MSSELTSILSNTFDYVGMEFIDTLLREITLQTKVQSTLLLQLLSAEEYNELSSIYKKDNFHVLQSSSSSPEIVSSPVHQDSTANQFLLIRSCYIDQPSMNSSLKDTMIPLSHLNPSSPYIKTLFNKEPILSLLNQQSETEQQEIERGIYPAYQQFIGLRLDHPHTKAILCVTDCHTMDTCKLNKVTHILEYVKTRCLNELNQLRRQEQLMSARDLAIVDAENKLKFLADMSHEIRTPMNAVIALTDLLLQERSTLNMEQIEHLEVIQTSGSHLLTIINDILDISKLNHDPKFKLESRRFSLRKCLKDTLNMARHQASMSQQNKVVYVLECPPDKDDNVPLPQLISQLENSGVLLRPLLHKKGKTVLPVIWKIDSDVPDHLLGDTMRLTQIMLNLCSNAVKFTKQGGIHIRIKRSTPTPLRTPSTQSKLDKRMTFKERYDAKIETIWNRAMQEKRDRNHASPNNGLVDEEVDYFGEKTVLEISVTDTGIGIPGDRLPKLFKSFSQIDISTARRYGGTGLGLAISSTLVNRMGGCVWVESEEGIGSRFALTLPMTVAPRGRNHSSDSTPLGFTGSPSSPGSTVSDSSSSVHSTLGNTNCVSNDIISPLSSAFFTFTTPTVTSSGSATSSHSGYFPATPVTFNQQQQQQQRPLLPRTSHQHLYTNEPYQQRSEPISIPQANQNTTQDQSFSPMAEDGHPLNPNPSLPPSSELETDQNKRINISGNNHAATNTGNTTARKNYNDLLSPATRNNRVSISKQHYHNRKPQTKEENLAKAHPLRILLAEDNILNQKIAISILKRLGYVDVAIANNGSEVLTLMKTSVFDVIFMDLYMPEMDGLEVTREIIKERTRQKSTTTETTNTPSSPTESNGTLLNSNDVYIIALTASASREDRQICIDAGMNDFISKPFTMTEMKSALKTCANKRKKRRKLTQKVADMDEVIDDVSTIVEDADEEGSASLEAEQHTTDDPMLDIETGAPHPH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NND0</accession>
    <name>A0A1C7NND0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Vacuolar protein sorting-associated protein 54</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">scat</name>
        <name evidence="11" type="ORF">A0J61_01419</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Golgi apparatus</location>
            <location evidence="1">trans-Golgi network</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the VPS54 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000045">
        <property type="protein sequence ID" value="OBZ90518.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NND0"/>
    <dbReference type="FunCoup" id="A0A1C7NND0">
        <property type="interactions" value="303"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NND0"/>
    <dbReference type="InParanoid" id="A0A1C7NND0"/>
    <dbReference type="OrthoDB" id="10259024at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000938">
        <property type="term" value="C:GARP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019905">
        <property type="term" value="F:syntaxin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006896">
        <property type="term" value="P:Golgi to vacuole transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042147">
        <property type="term" value="P:retrograde transport, endosome to Golgi"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.860">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039745">
        <property type="entry name" value="Vps54"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012501">
        <property type="entry name" value="Vps54_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019515">
        <property type="entry name" value="VPS54_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12965">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING 54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12965:SF0">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07928">
        <property type="entry name" value="Vps54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10475">
        <property type="entry name" value="Vps54_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="5" id="KW-0653">Protein transport</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Vacuolar protein sorting-associated protein 54 N-terminal" evidence="10">
        <location>
            <begin position="294"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="domain" description="Vacuolar protein sorting-associated protein 54 C-terminal" evidence="9">
        <location>
            <begin position="750"/>
            <end position="884"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="52"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="60"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004601"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00017665"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF07928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF10475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="OBZ90518.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="1005" mass="113884" checksum="D6607B1CC5CDC991" modified="2016-11-30" version="1">MSNNNTTPRSSIDNNIYGARLNQTSLKSEHADAPPLLIATNNISYSRPLARERPYARNETANSSNSSSRPPSIRSATSFGRPLGRFVTGQHARHQSTYSNFSTMSETALPWTTKDIGFNAISGVLNDPAKPKDLTKPSKGDIPPVTHASISRIKPSNFEAYLNHIGPAFERYHYNKLQNPPHHNNPNTEIAEEEEAALISPQFPFGKHQPRRTTRNPYSLPQHILSSESLLDDDESSKTPPRDLPMLENVPSIFFEPDFLLENPQVFDTVCEGADIVGNTGPNPPTSTNSILQEKLSYYLDTVEVHLLREIENRSSSFFEALSNLQALHQQTLDCVSQIHTIRQKMKQIQDTECKDGLEIIRLQVRKRNLEKLYRVTKTVRDIRATQPMIQALLGKGDYFAALDLIEETKLVLNNNRKSQSQDDEVDLSSIKALANFSAQLDEMQKAVGVMTQHDFLSTLLSDFTFILENIDLERAKQSLLNTNAQVMQPDLQKEKDLRDKLRPIVMGLLRTEMLLSTLREYREQLMIEIKDIIRKRYPASVLSQSTISSQEEQINSQLSKQLKAMPFSAFFDMLLDMFSALMKAIERTSIYHQLIASIASDQPEIEKESADILFSVADLAHVRCGKLIGFRNDQNALLNPTDFYRFSNVIRTFVVQCESMCKRTCFGLRGTMTTQQKAFIEHFHMERVKQEAQLIENEQWVASEVPSDFQSIVDNICDGHIASHLNELTSRSSQKGEKPTKHLVLDGYSFYVVGCSLLILKMFEDYLKCALNLDNPTLTIEIVHRLIEMLKLFNSRVCQVILGAGAMRSAGLKNITAKHLALASQSLAVMITLIPKLKHYVAHQLLTKSLSDPLLSEFDHAVEDYRNHQGEIHSKLVAIMNERFAAHAKAMQAIDWDQEAMETGKHANIYMETLVTETVRLHKVLSKYLPERDLKSVMSQVFQSFTTRLSVQITNTVIKTEKGKERLKRDVLFFNDRLRSLPQVDPPSHATIEAMDTLVVQDKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-06-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NNE9</accession>
    <name>A0A1C7NNE9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_03150</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000131">
        <property type="protein sequence ID" value="OBZ88794.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NNE9"/>
    <dbReference type="InParanoid" id="A0A1C7NNE9"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ88794.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="76" mass="9010" checksum="38C14802AE689EB8" modified="2016-11-30" version="1">MQHTFQKIDCQQRSETESAFWSNTVFHVDLQHKFQAKFGKITLNLSKKRIEVAGNHDKFKETTIDSKEAYNFNYQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NNU9</accession>
    <name>A0A1C7NNU9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">G-box-binding factor 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">GBF1</name>
        <name evidence="4" type="ORF">A0J61_01303</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000039">
        <property type="protein sequence ID" value="OBZ90650.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NNU9"/>
    <dbReference type="STRING" id="101091.A0A1C7NNU9"/>
    <dbReference type="InParanoid" id="A0A1C7NNU9"/>
    <dbReference type="OrthoDB" id="2257100at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12193">
        <property type="entry name" value="bZIP_GCN4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004827">
        <property type="entry name" value="bZIP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046347">
        <property type="entry name" value="bZIP_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031106">
        <property type="entry name" value="C/EBP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23334:SF20">
        <property type="entry name" value="BASIC LEUCINE ZIPPER 24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23334">
        <property type="entry name" value="CCAAT/ENHANCER BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07716">
        <property type="entry name" value="bZIP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00338">
        <property type="entry name" value="BRLZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57959">
        <property type="entry name" value="Leucine zipper domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50217">
        <property type="entry name" value="BZIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00036">
        <property type="entry name" value="BZIP_BASIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BZIP" evidence="3">
        <location>
            <begin position="141"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="56"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="159"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="68"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OBZ90650.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="225" mass="25142" checksum="F5D8217448567982" modified="2016-11-30" version="1">MNSQYQEPQFSQPQQDQLSPSETYIQPSSMMDSWLTDSFSQSGLFSQDLIHLLQQQLLPDSPPISPPETKQQPSSVSPAVPLFPDIHPTSTPTPIVTHKLPRLAPRPSTQLLTPVTPVISSPAPPTPIISNKRKAAPLEDEDEIALKRQKNTDAARRSRLKKLMKMESLEKRVSELESDNNQLNTRIAVLESEKSGLTSKDQSLQERIRVLEAQLAEAHRALTSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NPF3</accession>
    <name>A0A1C7NPF3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Glycerophosphodiester phosphodiesterase GDE1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">GDE1</name>
        <name evidence="8" type="ORF">A0J61_01187</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000034">
        <property type="protein sequence ID" value="OBZ90779.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NPF3"/>
    <dbReference type="FunCoup" id="A0A1C7NPF3">
        <property type="interactions" value="72"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NPF3"/>
    <dbReference type="InParanoid" id="A0A1C7NPF3"/>
    <dbReference type="OrthoDB" id="197419at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047389">
        <property type="term" value="F:glycerophosphocholine phosphodiesterase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046475">
        <property type="term" value="P:glycerophospholipid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.190">
        <property type="entry name" value="Phosphatidylinositol (PI) phosphodiesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057506">
        <property type="entry name" value="C2_GPCPD1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051578">
        <property type="entry name" value="GDPD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030395">
        <property type="entry name" value="GP_PDE_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017946">
        <property type="entry name" value="PLC-like_Pdiesterase_TIM-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004331">
        <property type="entry name" value="SPX_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22958:SF1">
        <property type="entry name" value="GLYCEROPHOSPHOCHOLINE PHOSPHODIESTERASE GPCPD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22958">
        <property type="entry name" value="GLYCEROPHOSPHORYL DIESTER PHOSPHODIESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13637">
        <property type="entry name" value="Ank_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25329">
        <property type="entry name" value="C2_GDE1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03009">
        <property type="entry name" value="GDPD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03105">
        <property type="entry name" value="SPX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51695">
        <property type="entry name" value="PLC-like phosphodiesterases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51704">
        <property type="entry name" value="GP_PDE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50007">
        <property type="entry name" value="PIPLC_X_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51382">
        <property type="entry name" value="SPX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="SPX" evidence="6">
        <location>
            <begin position="1"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="4">
        <location>
            <begin position="283"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="4">
        <location>
            <begin position="466"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="domain" description="GP-PDE" evidence="7">
        <location>
            <begin position="752"/>
            <end position="1113"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="368"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="537"/>
            <end position="560"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="860"/>
            <end position="934"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="368"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="545"/>
            <end position="557"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="877"/>
            <end position="889"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="890"/>
            <end position="907"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51704"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OBZ90779.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="1116" mass="124476" checksum="933D2A31C48CF93A" modified="2016-11-30" version="1">MKFGKTLLSNQIPEWSRNYLSYKSLKGEIKSVANHLPASEDDITAIVFHLDRELEKVNTFYVYKQSMIHRRLWILQEKLNDENDEVALALKETRSQMDKLMWFAELNSKGFRKILKKLDKKIGLDMQHIYWETKVAVLPFATSTQLRKELDQVAEWISTLTSSAELEQNLKSNNNNSSLKLARYTSKNEDIFKAVQQDNQQELQALLKEDTRINDTIVELAVEHESLACLDYLVSTLGLSLLNNKDINERNLLHRACLRASSTKMADRLLTLAPSLSLQKDFAGRRPLHYAAEKNNPELVRLLMKHAMDHQAYSMQDGFAANAWQDREGFTPLFFGIIHGSTKAVEAMIEVGHIQNIDESIASTHQLPTTSMDGSFSSEESKDEEGAEHVPDYARSLHHPSSVALACKLSNPELLTLLINKGASVDLADEDGDTPLLFAIRSHFIEGIQVLIEQGHVNVDLSERVNGWTPLMVAAMEGFQDVVEILLKANANKETVDFNGWTATDHAVFRGYLDIGRLTLPKDPKAYLDPSVRAKLTGTSDDESGSSTPNSSVSKQSKSVRKSVSKASRLYGHKYLTDLCMIVIRLGSNDVRNPLCHQFIELSKEFLGEDQEKRLSLSVSATNASGEFPIIDLPSEFKHDFYPEPIVLFTPNPNEVTLRFDLIETFGSSRESNVLARGTSVLAGDFIFSKLKGFKGPIEKASLRGQQKVPLVQAKNLDCIGSLGFEFLVITPFKHKNLRVGDRYTYYKSVDTQVIGHRGSGMNKKGAKLQVGENTVLSFVTAASLGAEYVEFDVQLTKDLVPVIYHDWTVTETGYDIPLNSITLEQFLNLRRSGHIKEYHTGVSDGKHGIVVPRSSSITSLEKPLPLTPPLTDQHINRANGSNGTQTPNSVRPSRSLSFSSSSPSRFGGFTDPFEQTRTSKAGKMKGNGPETIQGPFTTLAETLRSVPKSAGFNIEVKYPMVDEAEQDEMTSFQELNVYVDTILECVYDNVEQDRHVIFSSFHPEICLALNLKQPNYPVFFLTDAGTLPMADIRCNSLQEAVRFAKQADLLGIVAASEPILEAPRMVQVIKEMGLLLFTYGVLNNEVENAIAQKCYGVDAVIVDSVLPVRKGLRGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NQE4</accession>
    <name>A0A1C7NQE4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Solute carrier family 2, facilitated glucose transporter member 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">SLC2A2</name>
        <name evidence="9" type="ORF">A0J61_00712</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000017">
        <property type="protein sequence ID" value="OBZ91238.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NQE4"/>
    <dbReference type="STRING" id="101091.A0A1C7NQE4"/>
    <dbReference type="InParanoid" id="A0A1C7NQE4"/>
    <dbReference type="OrthoDB" id="4540492at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015149">
        <property type="term" value="F:hexose transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045263">
        <property type="entry name" value="GLUT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23503:SF8">
        <property type="entry name" value="FACILITATED GLUCOSE TRANSPORTER PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23503">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00171">
        <property type="entry name" value="SUGRTRNSPORT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00216">
        <property type="entry name" value="SUGAR_TRANSPORT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00217">
        <property type="entry name" value="SUGAR_TRANSPORT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0762">Sugar transport</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="19"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="73"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="105"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="129"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="161"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="194"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="329"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="364"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="394"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="422"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="8">
        <location>
            <begin position="19"/>
            <end position="451"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OBZ91238.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="451" mass="48702" checksum="16298297F3C474B1" modified="2016-11-30" version="1">MNEKTCQTISSMDLLYPRYMVFCVFAASFTFFSTGWVTGSPNLPGAVTHLCEQGDLHVANPVFPDCLPMGTSMWGFAVASFCIGGLIGGIAGGTIQTRLGRRKAIMCNTIGYIVGGILIGVSVSPAMFVVGRIICGFSCGLGTVATPVYVGEIATIKSRGLMGTINQLMICFGILATSLVGLPLSHVPLWRVNYALGAAPAILQAILMLFCTESPRYLVSINKIDLARTCLQKLRPGSDVTLELCSMIEGQLGSEAAAAYLASDGYFQSKIPSEETIMETISDKEKVYGSDVSSQLPTPPPMYEQESKNQMRSPMNVVEIFRDPIIRKITCIVIFIHAAQQLIGINAVMYYSTDMFGVVFDSNMASYMAIVCYAINVISTFPAIFLVDRLGRRVLLLVSEVGAVVCSILLAIGYIYNKGPLMVFSIFGYVFLFGVGIAPIPWILTSEVAPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NRH9</accession>
    <name>A0A1C7NRH9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_00257</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000005">
        <property type="protein sequence ID" value="OBZ91703.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NRH9"/>
    <dbReference type="InParanoid" id="A0A1C7NRH9"/>
    <dbReference type="OrthoDB" id="2237582at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000776">
        <property type="term" value="C:kinetochore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000070">
        <property type="term" value="P:mitotic sister chromatid segregation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013950">
        <property type="entry name" value="Mis14/Nsl1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08641">
        <property type="entry name" value="Mis14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ91703.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="194" mass="22280" checksum="3E6EE1FDFB329A75" modified="2016-11-30" version="1">MNSQTTKDRLASESRDLLAIRDLLDVYCQKVVDKELPSATSDLRRKRVLLEPKLKESMDKIISSLAECLSIVDFEGDIDSTSFNRTEPVDENLKQKVKDKQQELDNTLSKAIEMRNTYPKKQLNIALEICAAARQEIDKVEYKIVSQEQSTIDTIEVTDNTVEAYRDAIRLSKNIIKKTQYLPEKIETILDILE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NRW2</accession>
    <name>A0A1C7NRW2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_00112</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000002">
        <property type="protein sequence ID" value="OBZ91857.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NRW2"/>
    <dbReference type="InParanoid" id="A0A1C7NRW2"/>
    <dbReference type="OrthoDB" id="2279373at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ91857.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="97" mass="11178" checksum="DAED4BD5F1FF9A23" modified="2016-11-30" version="1">MLLTGGLNDSKMPNDVVRFLGSNEPLKELVDGGSFFKGTISSKKFAKLNKSITILQMDMCMRVILQERFYNRRSYERQEQFAFGLTDFSHFSAKEIQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NTR7</accession>
    <name>A0A1C7NTR7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">peptide-methionine (S)-S-oxide reductase</fullName>
            <ecNumber evidence="2">1.8.4.11</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">Peptide-methionine (S)-S-oxide reductase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">mxr1_1</name>
        <name evidence="8" type="ORF">A0J61_01048</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>L-methionyl-[protein] + [thioredoxin]-disulfide + H2O = L-methionyl-(S)-S-oxide-[protein] + [thioredoxin]-dithiol</text>
            <dbReference type="Rhea" id="RHEA:14217"/>
            <dbReference type="Rhea" id="RHEA-COMP:10698"/>
            <dbReference type="Rhea" id="RHEA-COMP:10700"/>
            <dbReference type="Rhea" id="RHEA-COMP:12313"/>
            <dbReference type="Rhea" id="RHEA-COMP:12315"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:16044"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:44120"/>
            <dbReference type="ChEBI" id="CHEBI:50058"/>
            <dbReference type="EC" id="1.8.4.11"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>[thioredoxin]-disulfide + L-methionine + H2O = L-methionine (S)-S-oxide + [thioredoxin]-dithiol</text>
            <dbReference type="Rhea" id="RHEA:19993"/>
            <dbReference type="Rhea" id="RHEA-COMP:10698"/>
            <dbReference type="Rhea" id="RHEA-COMP:10700"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:50058"/>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
            <dbReference type="ChEBI" id="CHEBI:58772"/>
            <dbReference type="EC" id="1.8.4.11"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the MsrA Met sulfoxide reductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.8.4.11" evidence="2"/>
    <dbReference type="EMBL" id="LUGH01000029">
        <property type="protein sequence ID" value="OBZ90894.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NTR7"/>
    <dbReference type="FunCoup" id="A0A1C7NTR7">
        <property type="interactions" value="468"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NTR7"/>
    <dbReference type="InParanoid" id="A0A1C7NTR7"/>
    <dbReference type="OrthoDB" id="77405at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008113">
        <property type="term" value="F:peptide-methionine (S)-S-oxide reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034599">
        <property type="term" value="P:cellular response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1060.10:FF:000006">
        <property type="entry name" value="Peptide methionine sulfoxide reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1060.10">
        <property type="entry name" value="Peptide methionine sulphoxide reductase MsrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01401">
        <property type="entry name" value="MsrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002569">
        <property type="entry name" value="Met_Sox_Rdtase_MsrA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036509">
        <property type="entry name" value="Met_Sox_Rdtase_MsrA_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00401">
        <property type="entry name" value="msrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43774">
        <property type="entry name" value="PEPTIDE METHIONINE SULFOXIDE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43774:SF1">
        <property type="entry name" value="PEPTIDE METHIONINE SULFOXIDE REDUCTASE MSRA 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01625">
        <property type="entry name" value="PMSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55068">
        <property type="entry name" value="Peptide methionine sulfoxide reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptide methionine sulphoxide reductase MsrA" evidence="7">
        <location>
            <begin position="5"/>
            <end position="159"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005591"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00030643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00047806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00048782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01625"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OBZ90894.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="166" mass="19165" checksum="9F3E5CB1087799F5" modified="2016-11-30" version="1">MTTEKATFAAGCFWGVEHIYNKHFKQFDIKCKVGYIGGDIENPNYRQVCSGTTNHAEAVQIDFDPAKVSYASLVEFFYRMHDPTQLNQQGPDRGTQYRSAIFYHSPEQKEVAEKVTAEIQEKHFKGKKIVTELIPAGVFYDAESYHQKYLEKNPSGYECPTHFLHW</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NUZ2</accession>
    <name>A0A1C7NUZ2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 13">Phosphomannomutase</fullName>
            <ecNumber evidence="5 13">5.4.2.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">PMM1</name>
        <name evidence="14" type="ORF">A0J61_00631</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">Involved in the synthesis of the GDP-mannose and dolichol-phosphate-mannose required for a number of critical mannosyl transfer reactions.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>alpha-D-mannose 1-phosphate = D-mannose 6-phosphate</text>
            <dbReference type="Rhea" id="RHEA:11140"/>
            <dbReference type="ChEBI" id="CHEBI:58409"/>
            <dbReference type="ChEBI" id="CHEBI:58735"/>
            <dbReference type="EC" id="5.4.2.8"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="12">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2 13">Nucleotide-sugar biosynthesis; GDP-alpha-D-mannose biosynthesis; alpha-D-mannose 1-phosphate from D-fructose 6-phosphate: step 2/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4 13">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 13">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 13">Belongs to the eukaryotic PMM family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.4.2.8" evidence="5 13"/>
    <dbReference type="EMBL" id="LUGH01000015">
        <property type="protein sequence ID" value="OBZ91304.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="FunCoup" id="A0A1C7NUZ2">
        <property type="interactions" value="448"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NUZ2"/>
    <dbReference type="InParanoid" id="A0A1C7NUZ2"/>
    <dbReference type="OrthoDB" id="10264771at2759"/>
    <dbReference type="UniPathway" id="UPA00126">
        <property type="reaction ID" value="UER00424"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004615">
        <property type="term" value="F:phosphomannomutase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042803">
        <property type="term" value="F:protein homodimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0180047">
        <property type="term" value="P:dolichol phosphate mannose biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009298">
        <property type="term" value="P:GDP-mannose biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006013">
        <property type="term" value="P:mannose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006487">
        <property type="term" value="P:protein N-linked glycosylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02585">
        <property type="entry name" value="HAD_PMM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1240.20:FF:000001">
        <property type="entry name" value="Phosphomannomutase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1240.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006379">
        <property type="entry name" value="HAD-SF_hydro_IIB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005002">
        <property type="entry name" value="PMM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043169">
        <property type="entry name" value="PMM_cap"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01484">
        <property type="entry name" value="HAD-SF-IIB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10466">
        <property type="entry name" value="PHOSPHOMANNOMUTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10466:SF0">
        <property type="entry name" value="PHOSPHOMANNOMUTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03332">
        <property type="entry name" value="PMM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00445">
        <property type="entry name" value="alpha-phosphomannomutase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01143">
        <property type="entry name" value="C2.B.3:_Phosphomannomutase_Lik"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01140">
        <property type="entry name" value="C2.B:_Phosphomannomutase_and_P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00003">
        <property type="entry name" value="Haloacid_Dehalogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 13" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9 13" id="KW-0413">Isomerase</keyword>
    <keyword evidence="8 12" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7 12" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" description="Nucleophile" evidence="10">
        <location>
            <position position="20"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor/acceptor" evidence="10">
        <location>
            <position position="22"/>
        </location>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="20"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="22"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="29"/>
        </location>
        <ligand>
            <name>alpha-D-mannose 1-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58409"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="131"/>
        </location>
        <ligand>
            <name>alpha-D-mannose 1-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58409"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="142"/>
        </location>
        <ligand>
            <name>alpha-D-mannose 1-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58409"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="149"/>
        </location>
        <ligand>
            <name>alpha-D-mannose 1-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58409"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="187"/>
        </location>
        <ligand>
            <name>alpha-D-mannose 1-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58409"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="189"/>
        </location>
        <ligand>
            <name>alpha-D-mannose 1-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58409"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="217"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="229"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004699"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009736"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR605002-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR605002-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR605002-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU361118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="OBZ91304.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="254" mass="29189" checksum="FEA56D6C65B66CEA" modified="2016-11-30" version="1">MSPVNEFSDRQHPDTIVLFDVDGTLTPARAFVSQEMKDTLASLRKKAVIGFVGGSDISKQYEQLGESILQDFDFCFAENGLTAYRLGKQMASQSFIQWIGDEEYNKLVNFILRYIADMDIPKKRGTFIEFRNXMINVSPIGRNCSREERNEFEKYDLARGLRQKFVDALKKEFSHLALTYSIGGQISFDVFPTGWDKTYCLRHVKEDGFKNIHFFGDKTFEGGNDFEIYTHPDVQGHSVKCPEDTMRILAELFP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7LU89</accession>
    <name>A0A1C7LU89_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_11902</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01002669">
        <property type="protein sequence ID" value="OBZ68361.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7LU89"/>
    <dbReference type="InParanoid" id="A0A1C7LU89"/>
    <dbReference type="OrthoDB" id="2302136at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ68361.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="202" mass="23284" checksum="C80386A6DC772D18" modified="2016-11-30" version="1">MAPRSASTQQQLTELVASIQQFTTELRQEMREELMAQRAVLDDQQANFARQLEALSDRDRLVLEQLQQPRPGQLGSSALAPVVSRFTHAKPNKGGERQKIMTLLEQVFVEKDQDDLDIMYKKIGRKVKLVCDFYAEKEENHGKFYRNVSPMDSISLASSVVDKLMEKDEEFQFLLECEGLWPVEFLISLCWSNKSKAINKKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MTC8</accession>
    <name>A0A1C7MTC8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Helitron helicase-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_11828</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01002545">
        <property type="protein sequence ID" value="OBZ80123.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MTC8"/>
    <dbReference type="STRING" id="101091.A0A1C7MTC8"/>
    <dbReference type="InParanoid" id="A0A1C7MTC8"/>
    <dbReference type="OrthoDB" id="2447509at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45786:SF74">
        <property type="entry name" value="ATP-DEPENDENT DNA HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45786">
        <property type="entry name" value="DNA BINDING PROTEIN-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="217"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ80123.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="217" mass="24326" checksum="7C73ADCCA18FFD03" modified="2016-11-30" version="1" fragment="single">MDLSAVPSSWNDGGLMNCVCTHCGALMWTHERVSTTSRHRPEFQLCCYTRKSVLPSLQSTPSEIAGYLKSNNVNYKEFQKNIRLYNSSLCFTSLGVSLDLNLANNRSGAYTFRIQGSPYHLVGSGVPTEGSNPKFAQLYIYDAEHELQNRHAIAPSVNIATLEKIKEMMHWLNPFVSIFKSTAQVVNEQRSNSNTESQQNNISSLENIKLVFRAEGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-06-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MVS7</accession>
    <name>A0A1C7MVS7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_11074</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001647">
        <property type="protein sequence ID" value="OBZ80877.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="InParanoid" id="A0A1C7MVS7"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ80877.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="124" mass="14332" checksum="1A3754736258AA8E" modified="2016-11-30" version="1">MRFEIKKVKGILSFGISDNNAFCPLEYWYNGIECSQIVXDTYKIAVTIMDSNKANKPTLMVPICDVILEKTPIVLQLEAYHYNILIVDEDCVYSPINPIYSKIDLDIKYIEEKTKDNIKYSVKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MW41</accession>
    <name>A0A1C7MW41_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_10939</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the MYG1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001526">
        <property type="protein sequence ID" value="OBZ81012.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MW41"/>
    <dbReference type="FunCoup" id="A0A1C7MW41">
        <property type="interactions" value="1214"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7MW41"/>
    <dbReference type="InParanoid" id="A0A1C7MW41"/>
    <dbReference type="OrthoDB" id="10265310at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003226">
        <property type="entry name" value="MYG1_exonuclease"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11215">
        <property type="entry name" value="METAL DEPENDENT HYDROLASE - RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11215:SF1">
        <property type="entry name" value="MYG1 EXONUCLEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03690">
        <property type="entry name" value="MYG1_exonuc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="233"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010105"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ81012.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="233" mass="26045" checksum="959602CFA3936406" modified="2016-11-30" version="1" fragment="single">MLKMVKTIGTHSGHFHCDEALAVSLLKKTKEFNDASLIRTRDASKLAECDIIVDVGGVYDPATHRYDHHQRGFTETFDAEHKTKLSSAGLVYKHFGKEVIMNVLGKTEIDSDVEMLYQKTYDGFVESLDANDNGISAYPSNINPLFKDSPTSLYHRVAQKNPGWNEPLNDAEIDARFVEASDMAGSELIGYVKRLQTSWLPARSLVVEALDKATEIHSSGRVIALERSCPWKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MWF8</accession>
    <name>A0A1C7MWF8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Fork-head transcriptional regulator 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">FKH2_1</name>
        <name evidence="10" type="ORF">A0J61_10809</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001410">
        <property type="protein sequence ID" value="OBZ81142.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MWF8"/>
    <dbReference type="FunCoup" id="A0A1C7MWF8">
        <property type="interactions" value="200"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7MWF8"/>
    <dbReference type="InParanoid" id="A0A1C7MWF8"/>
    <dbReference type="OrthoDB" id="5954824at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd20024">
        <property type="entry name" value="FH_FOXJ2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd22701">
        <property type="entry name" value="FHA_FKH1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.10:FF:000030">
        <property type="entry name" value="Forkhead box protein K2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.200.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000253">
        <property type="entry name" value="FHA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001766">
        <property type="entry name" value="Fork_head_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008984">
        <property type="entry name" value="SMAD_FHA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018122">
        <property type="entry name" value="TF_fork_head_CS_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030456">
        <property type="entry name" value="TF_fork_head_CS_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45881">
        <property type="entry name" value="CHECKPOINT SUPPRESSOR 1-LIKE, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45881:SF1">
        <property type="entry name" value="FORK HEAD PROTEIN HOMOLOG 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00498">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00250">
        <property type="entry name" value="Forkhead"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00053">
        <property type="entry name" value="FORKHEAD"/>
    </dbReference>
    <dbReference type="SMART" id="SM00339">
        <property type="entry name" value="FH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00240">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49879">
        <property type="entry name" value="SMAD/FHA domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50006">
        <property type="entry name" value="FHA_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00657">
        <property type="entry name" value="FORK_HEAD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00658">
        <property type="entry name" value="FORK_HEAD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50039">
        <property type="entry name" value="FORK_HEAD_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5 6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="FHA" evidence="8">
        <location>
            <begin position="81"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="domain" description="Fork-head" evidence="9">
        <location>
            <begin position="248"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="Fork-head" evidence="6">
        <location>
            <begin position="248"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="339"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="360"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="10">
        <location>
            <position position="398"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50039"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OBZ81142.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="398" mass="45203" checksum="DDC7B2479ED81ACA" modified="2016-11-30" version="1" fragment="single">MLVAKHHPQNEMTASCFSCIEDQLNDRKRVESQSLKACPSVLFTSMASTEQTVTDSSKETVQAYAKLEGEDFCYYIRTLQVTLGRRVKKPDSVDIPLGNIKSVSRQHARLFYNFTTQRFEMMVFGKNGAFVNEQFIEKGVTVPLENKTKIQIGEVSFVFLLPRMELTATTGGTDALSNEGFGYISAPQQLEKNCKLKKPLHLTSPIGSSTEQEAEQKKYTIDRNEINTDEWVESSPEDPSIYESKDIKPPYSYASLIAQAISSSRNKRMTLNGIYTFITTNYPYYQMASNGWQNSIRHNLSLNKAFVKVPRKDSEPGKGAFWTIDESAEGQFIKTTIPKKSKRSGTYSHKANKRRRVENGEEVLDEDEDDEGDEDIDEDDNDEMEEIEDIDCEDIDDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MWG7</accession>
    <name>A0A1C7MWG7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_10791</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001395">
        <property type="protein sequence ID" value="OBZ81160.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MWG7"/>
    <dbReference type="STRING" id="101091.A0A1C7MWG7"/>
    <dbReference type="InParanoid" id="A0A1C7MWG7"/>
    <dbReference type="OrthoDB" id="2415504at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ81160.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="180" mass="21559" checksum="60F07BB4934796FF" modified="2016-11-30" version="1">MFEVTNEWVVPYNPYLLKRYKARINGECCASIDAIKYINKGQDRTTLKISDSRNEVEKYLHARYIDPSEAVWHLFEFPFHEEDPIVILLPVHLLNKQTIYFDPQASHCDIRDKLNDDKTTLMAWFEYNQRNVDGRSYLYQEFSEHFVFDHTNKVWKPRKKGFAIGRMFYINPICGKPYHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MYB4</accession>
    <name>A0A1C7MYB4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_10181</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001061">
        <property type="protein sequence ID" value="OBZ81771.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="InParanoid" id="A0A1C7MYB4"/>
    <dbReference type="OrthoDB" id="2284342at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ81771.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="98" mass="11046" checksum="911F53F4BE4B6A4F" modified="2016-11-30" version="1" fragment="single">MSQVTPETITNIQNQLLETQQLLQRLVLQTQTNAADVNTSATXSPDMEEVDTSAPVHSIAVRQQFDWTPPEELAEMLNLKQSPFISSPMPDTQRRELI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MYJ4</accession>
    <name>A0A1C7MYJ4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">ketol-acid reductoisomerase (NADP(+))</fullName>
            <ecNumber evidence="6">1.1.1.86</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="16">Acetohydroxy-acid reductoisomerase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="15">Alpha-keto-beta-hydroxylacyl reductoisomerase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="21" type="primary">ilv-2</name>
        <name evidence="21" type="ORF">A0J61_10079</name>
    </gene>
    <organism evidence="21 22">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="21 22" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="21 22">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="4">Amino-acid biosynthesis; L-isoleucine biosynthesis; L-isoleucine from 2-oxobutanoate: step 2/4.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3">Amino-acid biosynthesis; L-valine biosynthesis; L-valine from pyruvate: step 2/4.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5 17">Belongs to the ketol-acid reductoisomerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="21">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.86" evidence="6"/>
    <dbReference type="EMBL" id="LUGH01001024">
        <property type="protein sequence ID" value="OBZ81872.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7MYJ4"/>
    <dbReference type="InParanoid" id="A0A1C7MYJ4"/>
    <dbReference type="OrthoDB" id="10255643at2759"/>
    <dbReference type="UniPathway" id="UPA00047">
        <property type="reaction ID" value="UER00056"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00049">
        <property type="reaction ID" value="UER00060"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016853">
        <property type="term" value="F:isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004455">
        <property type="term" value="F:ketol-acid reductoisomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009097">
        <property type="term" value="P:isoleucine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009099">
        <property type="term" value="P:L-valine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1040.10:FF:000003">
        <property type="entry name" value="Ketol-acid reductoisomerase, mitochondrial"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000167">
        <property type="entry name" value="Ketol-acid reductoisomerase, mitochondrial"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1040.10">
        <property type="entry name" value="N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase, domain 2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008927">
        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013328">
        <property type="entry name" value="6PGD_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013023">
        <property type="entry name" value="KARI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000506">
        <property type="entry name" value="KARI_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013116">
        <property type="entry name" value="KARI_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00465">
        <property type="entry name" value="ilvC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21371">
        <property type="entry name" value="KETOL-ACID REDUCTOISOMERASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21371:SF1">
        <property type="entry name" value="KETOL-ACID REDUCTOISOMERASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01450">
        <property type="entry name" value="KARI_C"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07991">
        <property type="entry name" value="KARI_N"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48179">
        <property type="entry name" value="6-phosphogluconate dehydrogenase C-terminal domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51851">
        <property type="entry name" value="KARI_C"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51850">
        <property type="entry name" value="KARI_N"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 17" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="14 17" id="KW-0100">Branched-chain amino acid biosynthesis</keyword>
    <keyword evidence="21" id="KW-0413">Isomerase</keyword>
    <keyword evidence="9 17" id="KW-0460">Magnesium</keyword>
    <keyword evidence="18" id="KW-0472">Membrane</keyword>
    <keyword evidence="8 17" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="10" id="KW-0521">NADP</keyword>
    <keyword evidence="12 17" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="22" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="18" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="18" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="396"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="domain" description="KARI N-terminal Rossmann" evidence="19">
        <location>
            <begin position="53"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="domain" description="KARI C-terminal knotted" evidence="20">
        <location>
            <begin position="243"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="domain" description="KARI N-terminal Rossmann" evidence="19">
        <location>
            <begin position="468"/>
            <end position="657"/>
        </location>
    </feature>
    <feature type="domain" description="KARI C-terminal knotted" evidence="20">
        <location>
            <begin position="658"/>
            <end position="775"/>
        </location>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="251"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="251"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="255"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="287"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="291"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="313"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="666"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="666"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="670"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="702"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="706"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="728"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="non-terminal residue" evidence="21">
        <location>
            <position position="775"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004864"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00010318"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00013102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00030209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00030593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="PROSITE" id="PS51850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="PROSITE" id="PS51851"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="EMBL" id="OBZ81872.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="775" mass="86541" checksum="FCF49A9A774ACD11" modified="2016-11-30" version="1" fragment="single">MSSRVFASALRRATTMARPSMTMMIRPAFQQTTIKATTTLQVRGMKTLDFGGTKETVYERADVPKEKLLETFKDDTIAVLGYGPQGRGQALNLRDNGVNVIIGQREGKTYQQAIEEGWVPGKNLFPVLDAVDKGTVVMNLLSDAYQKEIWPQMKPLITPGKTLYFSHGFSIVYKDQTHIEAPEGVDVVLVAPKGSGFTVRRLFQEGRGINSSFAVYQDASGKAKERTVALGIGIGSGYMYETTFEKEVYSDLFGERGVLMGAIQGLFQAQYEVLRANGHSPSEAFNETVEEATQSLYPLIGERGMDWMYSNCSTTAMRGALDWWKPFHHASKPVFEKLYQSVRDGSETARSLDRNSQPDYXIRFLIFISDWATQTFSDFICLEAFFYDAYKAEASFFFFYFILFFNFIMASRTFIAAARASIRSRPATTAFAVARPMSVLANNIRHTAVKSSIITQVRGMKTLDFGGTKETVYERADVPKEKLLETFKDDTIAVLGYGPQGRGQALNLRDNGVNVIIGQREGKTYQQAIEEGWVPGKNLFPVLDAVDKGTVVMNLLSDAYQKEIWPQMKPLITPGKTLYFSHGFSIVYKDQTNIEAPEGVDVVLVAPKGSGFTVRRLFQEGRGINSSFAVYQDASGKAKERTVALGIGIGSGYMYETTFEKEVYSDLFGERGVLMGAIQGLFQAQYEVLRANGHSPSEAFNETVEEATQSLYPLIGERGMDWMYSNCSTTAMRGALDWWKPFHNASKPVFEKLYQSVRDGSETARSLDRNSQPDY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MYQ1</accession>
    <name>A0A1C7MYQ1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">UDP-glucose 6-dehydrogenase</fullName>
            <ecNumber evidence="2">1.1.1.22</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">sgl</name>
        <name evidence="5" type="ORF">A0J61_09909</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>UDP-alpha-D-glucose + 2 NAD(+) + H2O = UDP-alpha-D-glucuronate + 2 NADH + 3 H(+)</text>
            <dbReference type="Rhea" id="RHEA:23596"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:58052"/>
            <dbReference type="ChEBI" id="CHEBI:58885"/>
            <dbReference type="EC" id="1.1.1.22"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Nucleotide-sugar biosynthesis; UDP-alpha-D-glucuronate biosynthesis; UDP-alpha-D-glucuronate from UDP-alpha-D-glucose: step 1/1.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.22" evidence="2"/>
    <dbReference type="EMBL" id="LUGH01000969">
        <property type="protein sequence ID" value="OBZ82045.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MYQ1"/>
    <dbReference type="STRING" id="101091.A0A1C7MYQ1"/>
    <dbReference type="InParanoid" id="A0A1C7MYQ1"/>
    <dbReference type="OrthoDB" id="5059218at2759"/>
    <dbReference type="UniPathway" id="UPA00038">
        <property type="reaction ID" value="UER00491"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003979">
        <property type="term" value="F:UDP-glucose 6-dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006024">
        <property type="term" value="P:glycosaminoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006065">
        <property type="term" value="P:UDP-glucuronate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000114">
        <property type="entry name" value="UDP-glucose 6-dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008927">
        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014027">
        <property type="entry name" value="UDP-Glc/GDP-Man_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036220">
        <property type="entry name" value="UDP-Glc/GDP-Man_DH_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014026">
        <property type="entry name" value="UDP-Glc/GDP-Man_DH_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028356">
        <property type="entry name" value="UDPglc_DH_euk"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11374:SF3">
        <property type="entry name" value="UDP-GLUCOSE 6-DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11374">
        <property type="entry name" value="UDP-GLUCOSE DEHYDROGENASE/UDP-MANNAC DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00984">
        <property type="entry name" value="UDPG_MGDP_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03720">
        <property type="entry name" value="UDPG_MGDP_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00984">
        <property type="entry name" value="UDPG_MGDP_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48179">
        <property type="entry name" value="6-phosphogluconate dehydrogenase C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52413">
        <property type="entry name" value="UDP-glucose/GDP-mannose dehydrogenase C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UDP-glucose/GDP-mannose dehydrogenase C-terminal" evidence="4">
        <location>
            <begin position="89"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="229"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00047473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OBZ82045.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="229" mass="25917" checksum="34F523271BAAD02A" modified="2016-11-30" version="1" fragment="single">TGADVDEVAYACGRDNRLGSRFLKASVGFGGSCFQKDILNLVYLSTQLNLPEVAEYWKQVYTLNEYQKKRFVKKIISTLFNTITNKRIAVLGFAFKKDTGDTRESAAITLIKDFIQENAHVAIYDPKVEHEQIYMDLTEPGVVDNRKQVEKSITICSSAYEAAQDADAVVIVTEWDEFKSEHLDYQKIYDNMHKPAFLFDGRLLLDAAEMRKIGFKVHIIGKNELAGTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MYT6</accession>
    <name>A0A1C7MYT6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_10384</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001147">
        <property type="protein sequence ID" value="OBZ81566.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MYT6"/>
    <dbReference type="InParanoid" id="A0A1C7MYT6"/>
    <dbReference type="OrthoDB" id="10645125at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="159"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="237"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="167"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="245"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="255"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="267"/>
            <end position="293"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ81566.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="293" mass="32992" checksum="C937A859F205C844" modified="2016-11-30" version="1">MKEEEEDKKTRPISRHIPAGLIMPRQLGTLSFDGQPLQLYHVFCQEDNAFSIIAVTQGRLDRLLPLQDDEMGVRVTVYGLLDPEILGIAGQPDIYIDLTFVDDIDVLDHQVPLSERIRTLYAEEMDRFRAWTSIPFVLHSYSPLPAACPIEVLAYADPDDSLPDRASSPSSNKENQPVQLDSNHEEEEERNVTVETMDPLPPSVVSSEEVLNVTVEIVGPSVSLVASTETITLTHVEKTPPAKPVLRRSPRLKRNPTEAKEEQKTVGAKKKRKIEVLRRSPRHANKKKVKYSC</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MYZ9</accession>
    <name>A0A1C7MYZ9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Chromosome segregation in meiosis protein 3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_10315</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001115">
        <property type="protein sequence ID" value="OBZ81636.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MYZ9"/>
    <dbReference type="STRING" id="101091.A0A1C7MYZ9"/>
    <dbReference type="InParanoid" id="A0A1C7MYZ9"/>
    <dbReference type="OrthoDB" id="437078at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006974">
        <property type="term" value="P:DNA damage response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031297">
        <property type="term" value="P:replication fork processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012923">
        <property type="entry name" value="Csm3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07962">
        <property type="entry name" value="Swi3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Chromosome segregation in meiosis protein 3" evidence="2">
        <location>
            <begin position="66"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="26"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="129"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="300"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="26"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="129"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="174"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="239"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="316"/>
            <end position="325"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ81636.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="325" mass="37760" checksum="8E13B1FE11D08CD6" modified="2016-11-30" version="1">MSEFDDLVLDDYELDGELTKQLDGLLNNTAAPSSETQDPEEATKKPVKRPKLDDESLLIYCFPLKQQEQDLKDLMQFYMFWANNLFPKLKFQDFAKRVTKPASTAAVKSQIKTWQEEFKERRQVRLEVENELNRQNESEDEQSRSQEEEEEASSEDDNRPLFFPITKPLPTNKPKPKKAVHRPHQASTHESNKSGEDETESSSSHRKRRMVSLDDSSDEEQEPSSSGTKNRQDVLALLQERRRQKEDAKKKEQEKAEQEELMKKKAELERSAEELTQEYLGEDVELALSDSELLLLNKDDTSFSDNELIQDLDTHQEEDESMTDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MZ35</accession>
    <name>A0A1C7MZ35_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">F5/8 type C domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_09906</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000969">
        <property type="protein sequence ID" value="OBZ82042.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MZ35"/>
    <dbReference type="STRING" id="101091.A0A1C7MZ35"/>
    <dbReference type="InParanoid" id="A0A1C7MZ35"/>
    <dbReference type="OrthoDB" id="1684102at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.260">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="77"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="13"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ82042.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="576" mass="66884" checksum="3E629BAE985EAAA1" modified="2016-11-30" version="1">MRSLVNHEKSSGHILSSRRQTHQSTPSSDLRGIHINISSDPFQHRIPPYIQRLWQESKLRRHLSLWKRRLAKRYEKLGWIEIALASVVIVGSCIVLLIHVGFFSGKKYQDWQLEHYYNDGLDEVDLLDKVYPDEGRLQTTAIVLIRDEPMYASTIVKQLCQYDMFSTITVWNDDPARTYTLDDILSNASYCTPNQVNVVNAPQSMGSAARYHACRLSKTPYCYFQDTPKNVLHLRSLYANFLRSPQLIHGQSADHDAFVDSQWRYCFSNTDIQLHTCYIDIESGTFVAKAMVTRFLSNNQDGVTGPFSDMYFMMFINQIPYQLEGDHGISKKQLEGQTLKHLEMGLAILYEDLKEGNEQASLKPYLKSTFERNVRASCQDDRCLFLTNKAILPDIQLFSYNPSLGIELSRDMHSDYIESNEDYRYMYAVDGNDQTSWKSLSNIEAGDYIGLDLLMPMRTPLRYRFLVRHPYRYRTTMAIQISYDGILWIKLHPSPHVTCQNMDLEDGTLQLLECKYVVTDTGYRYIRLESQMNHDFVFDVYDFSFSAKVKKDATGHLLDIDYDEDGIAFIEDDWMD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MZ56</accession>
    <name>A0A1C7MZ56_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Transposase Tc1-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_11536</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01002161">
        <property type="protein sequence ID" value="OBZ80414.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7MZ56"/>
    <dbReference type="InParanoid" id="A0A1C7MZ56"/>
    <dbReference type="OrthoDB" id="2255715at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="122"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ80414.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="122" mass="13605" checksum="CDB55C10B07FFF46" modified="2016-11-30" version="1" fragment="single">MPSHVSNDKRNDAKAMLLHGKSVREVASALGISKSXVSNIRRECDVDMRQQKGGRPAKMSKYLERKVLEGINTGTFLNAKDAQRYLADNQVVVSSDTVRKLLKRANLEAVHKPDVLPLTPKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MZ75</accession>
    <name>A0A1C7MZ75_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Mannose-1-phosphate guanyltransferase</fullName>
            <ecNumber evidence="4">2.7.7.13</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">GDP-mannose pyrophosphorylase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="15" type="primary">mpg1_1</name>
        <name evidence="15" type="ORF">A0J61_10241</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>alpha-D-mannose 1-phosphate + GTP + H(+) = GDP-alpha-D-mannose + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:15229"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:57527"/>
            <dbReference type="ChEBI" id="CHEBI:58409"/>
            <dbReference type="EC" id="2.7.7.13"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Nucleotide-sugar biosynthesis; GDP-alpha-D-mannose biosynthesis; GDP-alpha-D-mannose from alpha-D-mannose 1-phosphate (GTP route): step 1/1.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the transferase hexapeptide repeat family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.13" evidence="4"/>
    <dbReference type="EMBL" id="LUGH01001083">
        <property type="protein sequence ID" value="OBZ81709.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MZ75"/>
    <dbReference type="FunCoup" id="A0A1C7MZ75">
        <property type="interactions" value="375"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7MZ75"/>
    <dbReference type="InParanoid" id="A0A1C7MZ75"/>
    <dbReference type="OrthoDB" id="1733332at2759"/>
    <dbReference type="UniPathway" id="UPA00126">
        <property type="reaction ID" value="UER00930"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004475">
        <property type="term" value="F:mannose-1-phosphate guanylyltransferase (GTP) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071554">
        <property type="term" value="P:cell wall organization or biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009298">
        <property type="term" value="P:GDP-mannose biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd06425">
        <property type="entry name" value="M1P_guanylylT_B_like_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.160.10.10:FF:000017">
        <property type="entry name" value="Mannose-1-phosphate guanyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.550.10:FF:000013">
        <property type="entry name" value="mannose-1-phosphate guanyltransferase beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.10.10">
        <property type="entry name" value="Hexapeptide repeat proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="entry name" value="Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056729">
        <property type="entry name" value="GMPPB_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045233">
        <property type="entry name" value="GMPPB_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050486">
        <property type="entry name" value="Mannose-1P_guanyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005835">
        <property type="entry name" value="NTP_transferase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22572">
        <property type="entry name" value="SUGAR-1-PHOSPHATE GUANYL TRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25087">
        <property type="entry name" value="GMPPB_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00483">
        <property type="entry name" value="NTP_transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 15" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Nucleotidyl transferase" evidence="13">
        <location>
            <begin position="2"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="domain" description="Mannose-1-phosphate guanyltransferase C-terminal" evidence="14">
        <location>
            <begin position="254"/>
            <end position="362"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00018601"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00031190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00047343"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF00483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF25087"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="OBZ81709.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="363" mass="40111" checksum="2C54AF4389446EE5" modified="2016-11-30" version="1">MKALILVGGFGTRLRPLTLTLPKPLVEFANRPMILHQIEALSKAGVTDIVLAVNYRPEIMVSALKEYEKEYGVSITFSVETEPLGTAGPLALARDILGKDESPFFVLNSDVICDYPFEQIRDFHASHGDEGTIIVTKVDDPSKYGVVVNHPDSTKIERFVEKPQIFISNKINAGIYLFNPSVLDRIELKPTSIEKEIFPSIAHDGQLHTFDLDGFWMDVGQPKDYLTGTCLYLSHLSKHKPEQVANPNLDYVHKGNVMVHPTAKIGKGCRIGPNVVIGPNVVVGDGVRLQRCVIMEGAQVKDYAWVQSSIVGWHSSIGRWSRLEGCSVLGDDVTIKDEIYVNGGSILPHKSIANNITEPQIIM</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MZE2</accession>
    <name>A0A1C7MZE2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_09685</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000909">
        <property type="protein sequence ID" value="OBZ82265.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MZE2"/>
    <dbReference type="InParanoid" id="A0A1C7MZE2"/>
    <dbReference type="OrthoDB" id="2269854at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="105"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="105"/>
            <end position="126"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ82265.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="498" mass="56339" checksum="27ECAA37A599AB9F" modified="2016-11-30" version="1">MSTDNTTDIFSLSDLDNEQIYSAIHALQSSGQSVTISTIVAHLTNYINNKITSILKSENITYSKSRPDWENIGFLMFDRKIGISENLDSNRKIVSKKKCAIENTTTTPATTTTPATTTTPATTTTTGVSSSKQPKLSTADKASIIERFESLEESKMWKLSTGTIVEKQMKEFALICNYEHSSPVHSLVLNTTDLTWKKYFTSQEMQEIKQHRCKRLVDLPASLDQYIHQLQQSADVPALKQQLLTEKDDENCEWLRNCVLNYLNLFKCGYLPLTDQTEGDMLRRIWFFVDTAFDTSHISCRGGEKSSKTSSANLNSQRVLAGESPMQRKIMGRELDMVYFTQNSEYGSCECGRSEEQTKELYDGGFKMAKVSKDMLVDLCHKAPSSIRDFSVVGFLLFGAKFTLMTYDLPAGYVCRANSLSPMYLPEAAEDISIKLIDMLNATFRARLVMEENNLLVRRSRSRFDIAGLEEEVTIPSFKCVENHCKRRRSEANASERE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MZL2</accession>
    <name>A0A1C7MZL2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Uncharacterized protein PYUK71.03c</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">A0J61_09772</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000933">
        <property type="protein sequence ID" value="OBZ82178.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="FunCoup" id="A0A1C7MZL2">
        <property type="interactions" value="39"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7MZL2"/>
    <dbReference type="InParanoid" id="A0A1C7MZL2"/>
    <dbReference type="OrthoDB" id="1029639at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008289">
        <property type="term" value="F:lipid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006869">
        <property type="term" value="P:lipid transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00030">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd21678">
        <property type="entry name" value="SMP_TCB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.150">
        <property type="entry name" value="C2 domain"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000008">
        <property type="entry name" value="C2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035892">
        <property type="entry name" value="C2_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031468">
        <property type="entry name" value="SMP_LBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056910">
        <property type="entry name" value="TCB1-3_C2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052455">
        <property type="entry name" value="Tricalbin_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46980">
        <property type="entry name" value="TRICALBIN-1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46980:SF2">
        <property type="entry name" value="TRICALBIN-1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00168">
        <property type="entry name" value="C2"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24920">
        <property type="entry name" value="C2_TCB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25669">
        <property type="entry name" value="SMP_MUG190-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00360">
        <property type="entry name" value="C2DOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00239">
        <property type="entry name" value="C2"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49562">
        <property type="entry name" value="C2 domain (Calcium/lipid-binding domain, CaLB)"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50004">
        <property type="entry name" value="C2"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51847">
        <property type="entry name" value="SMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0445">Lipid transport</keyword>
    <keyword evidence="4" id="KW-0446">Lipid-binding</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="157"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="181"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="domain" description="SMP-LTD" evidence="9">
        <location>
            <begin position="222"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="domain" description="C2" evidence="8">
        <location>
            <begin position="446"/>
            <end position="563"/>
        </location>
    </feature>
    <feature type="domain" description="C2" evidence="8">
        <location>
            <begin position="594"/>
            <end position="704"/>
        </location>
    </feature>
    <feature type="domain" description="C2" evidence="8">
        <location>
            <begin position="728"/>
            <end position="846"/>
        </location>
    </feature>
    <feature type="domain" description="C2" evidence="8">
        <location>
            <begin position="1066"/>
            <end position="1195"/>
        </location>
    </feature>
    <feature type="domain" description="C2" evidence="8">
        <location>
            <begin position="1289"/>
            <end position="1416"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="894"/>
            <end position="920"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1249"/>
            <end position="1277"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="894"/>
            <end position="916"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="1254"/>
            <end position="1277"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OBZ82178.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="1436" mass="162196" checksum="749B4F61D5D7BFDB" modified="2016-11-30" version="1">MNPEDLDGNPQKGGSVMPSHLRRRSRTSQFEEFDYEDPTGLSRNEQLANAADLVPDLHGIAPSKGLDTDIDTHDTTSLQEALNASERKSVPPTMPGEFMSSKSSLIPDWYRTGWTALSENGENPGGALHMLATQFKKKGMLDDPIEDRLPSILYGGWYHNVAALFITAIVSYTLAKLKAGLGSIVLFCFVIASYYRVSTKRFRRDTRDDIQREIFKLKTEADEESVEWMNSFVQKFWLIFEPVLSALVVENLDNYISDYLPPYLDSIRLTTFTLGTKPFRVETVKTFLNTEPDTVCMDWRVSFIPNDLEDLTPEELDYKVNPKVIMVARIGKGRVGAGFPVLVENMAFSGYLRVKIKFMSRYPFVKLAQLSFLEKPQFDYVLKPLGTDHFGFDVNIIPGLQSFIREQVHGILGPLMYSPNVFTVDVDRFLAGDFDFGKFYSVFRSYSAEPKPNCHLDAANGVLAVTVYSTDRIKNIDGLVDGAPNPYIRFYLDHGQELDRTSVCENTFTPKWNETYYLKINNLNSLLSIELKTSRPGKKDRRLGTANFDLSVLDGETQAEQEELNLMMLRNGKYVTDVRVDLRYLPISKATKRDDGTVEPATESNSGVVRFKIHECQDLTSTAQIISPYVRLIVNGKEKKKTSVVKRSNDPKYEEAYEIVALDKTTLYLRVEVRNSADNDQLLGVFTSRLLDVIHQQERNNGWWPLTNNDTQNGQIRLSADWKPMMMSPISDFVGANGFDKPPIGIIRFTFWEARDLRNVEMVTNGKSDPYVRILSGHQIRGRTGVIDNNLNPEWGETIYVPVHSLKENFILEAMDWNARSRDKSLGITVFKVAEIIQQQIGDQSVNPDVWYESKGTPYDKWHKLHSADRQSSKGDLHFSAEFFPVLELPNDTTDSAADNQPLTKSNGNSNISSHSAPEVSISRPLPLRDLHGTYIRYTPDDLVDLHSYNSGILKIRIHEVQLSSPAYCYCQVIVDSLMPQYKTAKLRGDNLQFDEYADAFLKQVDFCRVAIEVKPAYSDEKDVHKLGYYIDTGSSVIRRVMKHRRRGYTIENDEGTWFKLMGTDGPARIRLSFDYYPMEKFVLNPDEGVDNQGILHVELVSAKNLMAADKSGTSDPYVVFNVNGEKVHKSDTIKKTLNPKWTNERFSVPIQSRVTASIRIEVFDWNHVKGHQPIGSGGITLRGDAVESFLSRMVDIPLDGVAGVSGSVQVKFTWHPRLSVNKKTPTSVLGANQTYVHDDVNLEVSGPLLENPGWSNSNMERISSESGESNDQRSYGRQSFESFQMHDDSGSLETSTIADTRTISDATGRAGIVTITLIEARGLRGVDKSGTSDPYVRVDVGKEQVFKTKYISKTLNPEWNETFTHHVGGEPYIFEFTVRDHNRLRSSVSLGQSRVNIWDLIKVDVPGGDLFNQWLPLFPAGSGELRVNIQFKATM</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MZW0</accession>
    <name>A0A1C7MZW0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_09550</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000876">
        <property type="protein sequence ID" value="OBZ82400.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MZW0"/>
    <dbReference type="InParanoid" id="A0A1C7MZW0"/>
    <dbReference type="OrthoDB" id="2291032at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="55"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="107"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="147"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="65"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="107"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="128"/>
            <end position="137"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ82400.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="203" mass="22397" checksum="B909F43BE821EC27" modified="2016-11-30" version="1">MLRVSSILYLEKVWSPPTVALLRETRSIDTSMDEANYTSEAIVKGLETVISSSHSVSTVDDDSPGMTNSLLSASSSVGPETPQQPTEVPNVTSDMIHSVCQYDEPVQSNASFSSRLSPKRILRGSRSNLKDDPKPSRRRSLFLEKFSHHPLNQEIPPLPNTDTSLVAADPPSSLAVFRRKSAKLSTKGKSLSKRIRRVISFHH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MZY5</accession>
    <name>A0A1C7MZY5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_09654</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000901">
        <property type="protein sequence ID" value="OBZ82298.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MZY5"/>
    <dbReference type="InParanoid" id="A0A1C7MZY5"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="26"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="33"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ82298.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="61" mass="6579" checksum="B053E361AC1BF29A" modified="2016-11-30" version="1" fragment="single">MLQSLAYAEFCMPLSSSSLFPVDEVSASTGEVDGDRSDYGSDHESEASNDNDSIPFESKPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N042</accession>
    <name>A0A1C7N042_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">transketolase</fullName>
            <ecNumber evidence="4">2.2.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="primary">TKL1_1</name>
        <name evidence="16" type="ORF">A0J61_09592</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>D-sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate = aldehydo-D-ribose 5-phosphate + D-xylulose 5-phosphate</text>
            <dbReference type="Rhea" id="RHEA:10508"/>
            <dbReference type="ChEBI" id="CHEBI:57483"/>
            <dbReference type="ChEBI" id="CHEBI:57737"/>
            <dbReference type="ChEBI" id="CHEBI:58273"/>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
            <dbReference type="EC" id="2.2.1.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Co(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:48828"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="13">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="13">Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+).</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="12">
            <name>thiamine diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58937"/>
        </cofactor>
        <text evidence="12">Binds 1 thiamine pyrophosphate per subunit. During the reaction, the substrate forms a covalent intermediate with the cofactor.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the transketolase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.2.1.1" evidence="4"/>
    <dbReference type="EMBL" id="LUGH01000886">
        <property type="protein sequence ID" value="OBZ82358.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="FunCoup" id="A0A1C7N042">
        <property type="interactions" value="454"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N042"/>
    <dbReference type="InParanoid" id="A0A1C7N042"/>
    <dbReference type="OrthoDB" id="10267175at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004802">
        <property type="term" value="F:transketolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006098">
        <property type="term" value="P:pentose-phosphate shunt"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07033">
        <property type="entry name" value="TPP_PYR_DXS_TK_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd02012">
        <property type="entry name" value="TPP_TK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.920:FF:000003">
        <property type="entry name" value="Transketolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.970:FF:000003">
        <property type="entry name" value="Transketolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.970:FF:000004">
        <property type="entry name" value="Transketolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.920">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.970">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029061">
        <property type="entry name" value="THDP-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009014">
        <property type="entry name" value="Transketo_C/PFOR_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055152">
        <property type="entry name" value="Transketolase-like_C_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005475">
        <property type="entry name" value="Transketolase-like_Pyr-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005478">
        <property type="entry name" value="Transketolase_bac-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049557">
        <property type="entry name" value="Transketolase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033247">
        <property type="entry name" value="Transketolase_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005474">
        <property type="entry name" value="Transketolase_N"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00232">
        <property type="entry name" value="tktlase_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43522">
        <property type="entry name" value="TRANSKETOLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43522:SF2">
        <property type="entry name" value="TRANSKETOLASE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02779">
        <property type="entry name" value="Transket_pyr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22613">
        <property type="entry name" value="Transketolase_C_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00456">
        <property type="entry name" value="Transketolase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00861">
        <property type="entry name" value="Transket_pyr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52518">
        <property type="entry name" value="Thiamin diphosphate-binding fold (THDP-binding)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52922">
        <property type="entry name" value="TK C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00801">
        <property type="entry name" value="TRANSKETOLASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 13" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6 13" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 12" id="KW-0786">Thiamine pyrophosphate</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Transketolase-like pyrimidine-binding" evidence="15">
        <location>
            <begin position="355"/>
            <end position="531"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="10">
        <location>
            <position position="417"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="28"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="68"/>
        </location>
        <ligand>
            <name>thiamine diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58937"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <begin position="116"/>
            <end position="118"/>
        </location>
        <ligand>
            <name>thiamine diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58937"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="157"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="158"/>
        </location>
        <ligand>
            <name>thiamine diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58937"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="187"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="187"/>
        </location>
        <ligand>
            <name>thiamine diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58937"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="189"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="263"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="263"/>
        </location>
        <ligand>
            <name>thiamine diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58937"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="358"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="385"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="443"/>
        </location>
        <ligand>
            <name>thiamine diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58937"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="467"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="475"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="479"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="526"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="site" description="Important for catalytic activity" evidence="14">
        <location>
            <position position="28"/>
        </location>
    </feature>
    <feature type="site" description="Important for catalytic activity" evidence="14">
        <location>
            <position position="263"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007131"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00049473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR605478-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR605478-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR605478-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR605478-4"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PIRSR" id="PIRSR605478-5"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="SMART" id="SM00861"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="OBZ82358.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="678" mass="73676" checksum="52F72B1ACEB8673D" modified="2016-11-30" version="1">MVQNIDQRAINTVRCLAADVVKGANSGHPGAPMGCAPIAHVLFNKFMTYNPKNPKFINRDRFVLSNGHACALQYIMLHIAGYDVSIEDLKHFRQLDSKTPGHPEVNDTPGIEVTTGPLGQGISNAVGLAAAEAHLAATFNKPGFEIFNNYTYCLLGDGCLQEGVSAEAISLAGHWKLGKLVALYDDNAITIDGSTEVSFTEDVLKRFESYGWHTIVVADGDNDIAALQKAIEEAHXVTDKPTLIKVKTTIGYGSLNQGEEKVHGAPLSEDDIKQVKEKFGFNPEEKYTVPQEVYDLYAAHAAEGAKAEEAWNALFAKYKAEFPQEASEIERRFSGKLPEGWEAALPRFTPADAPVATRKLSEGVLTALSDVLPELLGGSADLTGSNLTRWKKAVDFQHPSTNLGDYTGRYFRYGVREHGMFAIMNGLTAYGGSIPYGGTFLNFLTYGWGAARLSALSHFRVIYVMTHDSIGLGEDGPTHQPIETLVLTRATPNMLTFRPADGNEVSGTYLVAIENQHRPSVIALSRQNLPQLEGSSVEAVRRGGYVLQDAENAKLILVATGSEVSLAVDAAKELAAQGIPTRVVSMPCSEIYDEQPEEYKKSVLSAGLPIISIEALGITGWERYSHAHIGMRTFGASAPIKQLYNKFEITVDATVAKAKNVIAYYEKAGYVPEVGLDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N0V4</accession>
    <name>A0A1C7N0V4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">E2 ubiquitin-conjugating enzyme</fullName>
            <ecNumber evidence="1">2.3.2.23</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">UBC35</name>
        <name evidence="9" type="ORF">A0J61_09246</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="7">Belongs to the ubiquitin-conjugating enzyme family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.23" evidence="1"/>
    <dbReference type="EMBL" id="LUGH01000807">
        <property type="protein sequence ID" value="OBZ82703.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N0V4"/>
    <dbReference type="FunCoup" id="A0A1C7N0V4">
        <property type="interactions" value="726"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N0V4"/>
    <dbReference type="InParanoid" id="A0A1C7N0V4"/>
    <dbReference type="OrthoDB" id="7851174at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061631">
        <property type="term" value="F:ubiquitin conjugating enzyme activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd23813">
        <property type="entry name" value="UBCc_UBE2N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.110.10:FF:000020">
        <property type="entry name" value="Ubiquitin-conjugating enzyme E2 N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.110.10">
        <property type="entry name" value="Ubiquitin Conjugating Enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000608">
        <property type="entry name" value="UBC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023313">
        <property type="entry name" value="UBQ-conjugating_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016135">
        <property type="entry name" value="UBQ-conjugating_enzyme/RWD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24068">
        <property type="entry name" value="UBIQUITIN-CONJUGATING ENZYME E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00179">
        <property type="entry name" value="UQ_con"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00212">
        <property type="entry name" value="UBCc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54495">
        <property type="entry name" value="UBC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00183">
        <property type="entry name" value="UBC_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50127">
        <property type="entry name" value="UBC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 7" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="UBC core" evidence="8">
        <location>
            <begin position="2"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="active site" description="Glycyl thioester intermediate" evidence="6">
        <location>
            <position position="86"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012486"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU362109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OBZ82703.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="149" mass="16777" checksum="D35F71C769D2666A" modified="2016-11-30" version="1">MALPKRIIKETERLMADPAPGISATAHEDNLRYFDVVIAGPTQSPFEGGVFRLELFLPEDYPMGPPKVRFLTKIYHPNIDKLGRICLDILKDKWSPALQIRTVLLSIQALLSAPNPDDPLANDVASHWKEDEKGAIDQARQWTTMYAHS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N1I3</accession>
    <name>A0A1C7N1I3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Tubulin alpha chain</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="primary">TUBA1C</name>
        <name evidence="17" type="ORF">A0J61_09104</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="14">Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>GTP + H2O = GDP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:19669"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58189"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="13">
            <dbReference type="Rhea" id="RHEA:19670"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="4 14">Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
            <location evidence="2">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 14">Belongs to the tubulin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000774">
        <property type="protein sequence ID" value="OBZ82848.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N1I3"/>
    <dbReference type="FunCoup" id="A0A1C7N1I3">
        <property type="interactions" value="116"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N1I3"/>
    <dbReference type="InParanoid" id="A0A1C7N1I3"/>
    <dbReference type="OrthoDB" id="1662883at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005200">
        <property type="term" value="F:structural constituent of cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007017">
        <property type="term" value="P:microtubule-based process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02186">
        <property type="entry name" value="alpha_tubulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.600:FF:000005">
        <property type="entry name" value="Tubulin alpha chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1330.20:FF:000001">
        <property type="entry name" value="Tubulin alpha chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1440:FF:000008">
        <property type="entry name" value="Tubulin alpha chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.600">
        <property type="entry name" value="Helix hairpin bin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.20">
        <property type="entry name" value="Tubulin/FtsZ, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1440">
        <property type="entry name" value="Tubulin/FtsZ, GTPase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002452">
        <property type="entry name" value="Alpha_tubulin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013838">
        <property type="entry name" value="Beta-tubulin_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008280">
        <property type="entry name" value="Tub_FtsZ_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000217">
        <property type="entry name" value="Tubulin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037103">
        <property type="entry name" value="Tubulin/FtsZ-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018316">
        <property type="entry name" value="Tubulin/FtsZ_2-layer-sand-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036525">
        <property type="entry name" value="Tubulin/FtsZ_GTPase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023123">
        <property type="entry name" value="Tubulin_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017975">
        <property type="entry name" value="Tubulin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003008">
        <property type="entry name" value="Tubulin_FtsZ_GTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11588">
        <property type="entry name" value="TUBULIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00091">
        <property type="entry name" value="Tubulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03953">
        <property type="entry name" value="Tubulin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01162">
        <property type="entry name" value="ALPHATUBULIN"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01161">
        <property type="entry name" value="TUBULIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00864">
        <property type="entry name" value="Tubulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00865">
        <property type="entry name" value="Tubulin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55307">
        <property type="entry name" value="Tubulin C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52490">
        <property type="entry name" value="Tubulin nucleotide-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00227">
        <property type="entry name" value="TUBULIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00228">
        <property type="entry name" value="TUBULIN_B_AUTOREG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="12" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="11 14" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 14" id="KW-0493">Microtubule</keyword>
    <keyword evidence="8 14" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tubulin/FtsZ GTPase" evidence="15">
        <location>
            <begin position="47"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="domain" description="Tubulin/FtsZ 2-layer sandwich" evidence="16">
        <location>
            <begin position="246"/>
            <end position="391"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00049117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU000352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="SMART" id="SM00864"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="SMART" id="SM00865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="OBZ82848.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="446" mass="50090" checksum="C5E6C8ECACD5311E" modified="2016-11-30" version="1">MREIISLHVGQAGVQIGNACWELYCHEHGIQPNGHFIEGTHINDHSFETFFSETERGRHVPRTVMVDLEPSVIDETRNGVYRELFHPEQLINGKEDAANNYARGHYTVGKQMVDRVLDRIRRLADNCSGLQGFLVFHSFGGGTGSGFGALLMERLSVDYGKKSKLEFSIYPAPQLATSVVEPYNSVLTTHTTLEHSDVSFLVDNEAIYDICRRNLDISQPTYVNLNRLIAQVVSSITASLRFDGSLNVDLNEFQTNLVPYPRIHFPLVTYAPIISAAKAYHEQHSVPEITSSCFEANNQMVKCDPHSGKYMACCLLYRGDVVPKDTNAAISTIRTKRTIQFVDWCLTGFKVGINHQRPTVVPGSDMAEVQRAVCMLSSTTAISQAWSRLNHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDLAALEKDYEEVGADSVGESEMEEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N206</accession>
    <name>A0A1C7N206_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_08808</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000715">
        <property type="protein sequence ID" value="OBZ83142.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N206"/>
    <dbReference type="InParanoid" id="A0A1C7N206"/>
    <dbReference type="OrthoDB" id="2231921at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ83142.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="108" mass="12343" checksum="5A96B2512A2107E7" modified="2016-11-30" version="1">MLNSNTQANHWSPVFRSSSSFQQPTEVNLIEIDPPIQPNLPKPEPSNVVNITLDDLTGGEGFGFQVVRPKSMMDVINYLDRCNEKHTWLMSQVSETRLQCQRMMYSSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N273</accession>
    <name>A0A1C7N273_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Beta-lactamase-like protein 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">lactb2_0</name>
        <name evidence="6" type="ORF">A0J61_09221</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the metallo-beta-lactamase superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000801">
        <property type="protein sequence ID" value="OBZ82729.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N273"/>
    <dbReference type="STRING" id="101091.A0A1C7N273"/>
    <dbReference type="InParanoid" id="A0A1C7N273"/>
    <dbReference type="OrthoDB" id="17458at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044550">
        <property type="term" value="P:secondary metabolite biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07722">
        <property type="entry name" value="LACTB2-like_MBL-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.15.10:FF:000041">
        <property type="entry name" value="Metallo-beta-lactamase domain protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="entry name" value="Ribonuclease Z/Hydroxyacylglutathione hydrolase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047921">
        <property type="entry name" value="LACTB2-like_MBL-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050662">
        <property type="entry name" value="Sec-metab_biosynth-thioest"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23131">
        <property type="entry name" value="ENDORIBONUCLEASE LACTB2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23131:SF0">
        <property type="entry name" value="ENDORIBONUCLEASE LACTB2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00753">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00849">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="Metallo-hydrolase/oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Metallo-beta-lactamase" evidence="5">
        <location>
            <begin position="33"/>
            <end position="209"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007749"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OBZ82729.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="330" mass="37424" checksum="7F2166A45BED972A" modified="2016-11-30" version="1">MAEASVQSNLPVLPDFEQLSDRVWRLIYLHQTGTNTYLVGLGQRKVLIDCGDGHPGYVPLLIRSLQSIHPNAYISDILISHGHKDHWGGLNDILTSELNKNRKIQVHKYPLSEDARLLKYMTTFPTSAELIDLEDGQLFEIDQDTHVRVMHTPGHCEDHCSFYLEQEKVLFTADCILGHGSVAFDDLKEYMNSLQHIRNLNPGRLYPGHGQVVEDSLQKIDQYFSMRLAKEKLIIDTMIQNKDTPMSAYDIVEATSNNAKKKLEGYILISAAIVIGLHLIKLFSDGKAELVHPEEFVKAKGIDPYNSANVVDILHEKWRYIGDIHTISKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N2J1</accession>
    <name>A0A1C7N2J1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">RING-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_08630</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000683">
        <property type="protein sequence ID" value="OBZ83323.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N2J1"/>
    <dbReference type="InParanoid" id="A0A1C7N2J1"/>
    <dbReference type="OrthoDB" id="8062037at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13639">
        <property type="entry name" value="zf-RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="2">
        <location>
            <begin position="9"/>
            <end position="48"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ83323.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="222" mass="25690" checksum="1A6489E1112671E2" modified="2016-11-30" version="1">MLVINPDLCTFCGELSNEETFETANCDHRFHITCLTKQLQKNIICPICPNKIVVDIQRKQANTSLGSEVKAELHRHFDIMTKEINVLIKQQLEQGQELKTIYQALCDKSQSVRPEGIWTKLTEKANKTEGLSFEDRRRLLDQLIESYHAASKALWKHVFHQFDQFHQSVQALEKDKSILIESDSIKQKINDFKKEQLALDTLYANRYLKIARICSVPACLDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N2K4</accession>
    <name>A0A1C7N2K4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Poly(A) polymerase</fullName>
            <ecNumber evidence="11">2.7.7.19</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="19" type="primary">pla1_0</name>
        <name evidence="19" type="ORF">A0J61_08709</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="19 20" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19 20">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Polymerase that creates the 3'-poly(A) tail of mRNA's.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>RNA(n) + ATP = RNA(n)-3'-adenine ribonucleotide + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:11332"/>
            <dbReference type="Rhea" id="RHEA-COMP:14527"/>
            <dbReference type="Rhea" id="RHEA-COMP:17347"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:140395"/>
            <dbReference type="ChEBI" id="CHEBI:173115"/>
            <dbReference type="EC" id="2.7.7.19"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="13">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="13">Binds 2 magnesium ions. Also active with manganese.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 11">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 11">Belongs to the poly(A) polymerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="19">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.19" evidence="11"/>
    <dbReference type="EMBL" id="LUGH01000697">
        <property type="protein sequence ID" value="OBZ83241.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N2K4"/>
    <dbReference type="STRING" id="101091.A0A1C7N2K4"/>
    <dbReference type="InParanoid" id="A0A1C7N2K4"/>
    <dbReference type="OrthoDB" id="412748at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990817">
        <property type="term" value="F:poly(A) RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031123">
        <property type="term" value="P:RNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05402">
        <property type="entry name" value="NT_PAP_TUTase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.460.10:FF:000002">
        <property type="entry name" value="Poly(A) polymerase alpha, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1410.10:FF:000001">
        <property type="entry name" value="Putative poly(A) polymerase gamma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1410.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.460.10">
        <property type="entry name" value="Beta Polymerase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.590">
        <property type="entry name" value="Poly(A) polymerase predicted RNA binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043519">
        <property type="entry name" value="NT_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011068">
        <property type="entry name" value="NuclTrfase_I-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007012">
        <property type="entry name" value="PolA_pol_cen_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048840">
        <property type="entry name" value="PolA_pol_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007010">
        <property type="entry name" value="PolA_pol_RNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014492">
        <property type="entry name" value="PolyA_polymerase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10682">
        <property type="entry name" value="POLY A POLYMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10682:SF10">
        <property type="entry name" value="POLYNUCLEOTIDE ADENYLYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04928">
        <property type="entry name" value="PAP_central"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20750">
        <property type="entry name" value="PAP_NTPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04926">
        <property type="entry name" value="PAP_RNA-bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF018425">
        <property type="entry name" value="PolyA_polymerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81301">
        <property type="entry name" value="Nucleotidyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55003">
        <property type="entry name" value="PAP/Archaeal CCA-adding enzyme, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81631">
        <property type="entry name" value="PAP/OAS1 substrate-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 11 12" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9 13" id="KW-0460">Magnesium</keyword>
    <keyword evidence="15" id="KW-0472">Membrane</keyword>
    <keyword evidence="6 13" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 11" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="7 11 12" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10 11" id="KW-0539">Nucleus</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 11" id="KW-0808">Transferase</keyword>
    <keyword evidence="15" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="15" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="222"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="domain" description="Poly(A) polymerase nucleotidyltransferase" evidence="18">
        <location>
            <begin position="8"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="domain" description="Poly(A) polymerase central" evidence="17">
        <location>
            <begin position="206"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="domain" description="Poly(A) polymerase RNA-binding" evidence="16">
        <location>
            <begin position="357"/>
            <end position="512"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="517"/>
            <end position="576"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="14">
        <location>
            <begin position="517"/>
            <end position="528"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="14">
        <location>
            <begin position="563"/>
            <end position="576"/>
        </location>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <begin position="87"/>
            <end position="89"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <begin position="100"/>
            <end position="102"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="100"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="100"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>2</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="102"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="102"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>2</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="154"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="154"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>2</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="215"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="224"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <begin position="233"/>
            <end position="234"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRNR" id="PIRNR018425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR018425-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR018425-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF04926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF04928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="Pfam" id="PF20750"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="OBZ83241.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="576" mass="65387" checksum="D69F714DC71FB588" modified="2016-11-30" version="1">MRTQKYPGITEPLSLQSPTATDISMTDSLELCLQQNNMYEPPERIQQREAALHHLEKITKHFVRIVCQRKGLSKEKAEKAGGAIFTFGSYKLGVNSIDADIDTLCVVPCHVERRDFFIDMLALLKSTSCISDIMPVPDSFVPVIKFKYKDISIDLVCARLTLSEVPQDINLQNTHLLVGLDDKCVRSINGTRVAEDIMSLVPNLNTFRIALRCIKLWAERRAIYSNVLGFFGGVAWAILVARVCQLYPHATASVIVSKFFRIMTEWNWAAAPVILRHIEEGPPLSSSLRPWNNRVNMIDRSHRMPVITPSYPSMCATHNVTASTQRIILGEFAIANDIVDQILKGEASWSHLFSTHTFFQNYKYYLQVVVSCDHYHGFLSWAGFVEAKLRLLVTKLETVPAIALVHPYVHGLKREHLCQTSDDVWAVTHGQIFTPSQTVRRRKPAKIYTKTFYLGLYIRMRSDSRTLDLTRPICEFSRSIKSWSDYDNNHMGMIVENVKCSDLPEEVRTQMNHASTISKRALSKSPSPKLQPISPFIQEKQDVKKNVNKKPKTSNKNTEHSKSNNTNGSLMMTTSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N2N0</accession>
    <name>A0A1C7N2N0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Protein max</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">Max_2</name>
        <name evidence="9" type="ORF">A0J61_09013</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000755">
        <property type="protein sequence ID" value="OBZ82936.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N2N0"/>
    <dbReference type="STRING" id="101091.A0A1C7N2N0"/>
    <dbReference type="InParanoid" id="A0A1C7N2N0"/>
    <dbReference type="OrthoDB" id="8964853at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090575">
        <property type="term" value="C:RNA polymerase II transcription regulator complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.280.10">
        <property type="entry name" value="Helix-loop-helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011598">
        <property type="entry name" value="bHLH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036638">
        <property type="entry name" value="HLH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10328:SF3">
        <property type="entry name" value="PROTEIN MAX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10328">
        <property type="entry name" value="PROTEIN MAX MYC-ASSOCIATED FACTOR X"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00010">
        <property type="entry name" value="HLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00353">
        <property type="entry name" value="HLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47459">
        <property type="entry name" value="HLH, helix-loop-helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50888">
        <property type="entry name" value="BHLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0010">Activator</keyword>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="BHLH" evidence="8">
        <location>
            <begin position="73"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="57"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="199"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="129"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="199"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="222"/>
            <end position="236"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50888"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OBZ82936.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="297" mass="33857" checksum="C8B90C470759E104" modified="2016-11-30" version="1">MYPAQRGLYGHQKTTMTQFANPKHSMTSFDPFPFTNANLTDLPLRNTHSTPSHCADFELTRESNMKKPQSQEERRAEHNAIERARRETLNAKFQALAQALPNLMSYRRPSKSQIVEKALDWVKQGISREDRYRSQIIHLQRENKQLLAQLMQYQQDSNPSSNSLTSNTNSTASHVTAESVYAGMNSVYPWPVPGLMNSTQPITSSGSMDDVSRQSLSSPRTDDEDNISSANEEETEYQTSPYHISYQNNQDKQYFLQPDGSTHQALLNSFCSDIDVYPNEIQTNLALHHLNSHFQPI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N2N4</accession>
    <name>A0A1C7N2N4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Transcription initiation factor IIE subunit alpha</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">tfa1</name>
        <name evidence="6" type="ORF">A0J61_08695</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the TFIIE alpha subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000694">
        <property type="protein sequence ID" value="OBZ83258.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N2N4"/>
    <dbReference type="FunCoup" id="A0A1C7N2N4">
        <property type="interactions" value="400"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N2N4"/>
    <dbReference type="InParanoid" id="A0A1C7N2N4"/>
    <dbReference type="OrthoDB" id="361102at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005673">
        <property type="term" value="C:transcription factor TFIIE complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006367">
        <property type="term" value="P:transcription initiation at RNA polymerase II promoter"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039997">
        <property type="entry name" value="TFE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017919">
        <property type="entry name" value="TFIIE/TFIIEa_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002853">
        <property type="entry name" value="TFIIE_asu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021600">
        <property type="entry name" value="TFIIE_asu_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024550">
        <property type="entry name" value="TFIIEa/SarR/Rpc3_HTH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13097:SF7">
        <property type="entry name" value="GENERAL TRANSCRIPTION FACTOR IIE SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13097">
        <property type="entry name" value="TRANSCRIPTION INITIATION FACTOR IIE, ALPHA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11521">
        <property type="entry name" value="TFIIE-A_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02002">
        <property type="entry name" value="TFIIE_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00531">
        <property type="entry name" value="TFIIE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57783">
        <property type="entry name" value="Zinc beta-ribbon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51344">
        <property type="entry name" value="HTH_TFE_IIE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="6" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH TFE/IIEalpha-type" evidence="5">
        <location>
            <begin position="4"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="334"/>
            <end position="356"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51344"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OBZ83258.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="398" mass="45974" checksum="9ED17B0EC765A176" modified="2016-11-30" version="1">MDVLKTLVARIARAFYEPKYIAIIDALNGATPNSNGVKEEDLVYSLKMTPRDIHRICGKLKEDRLIKMANRMEPRKQDQRMVPKTYYYIDYKEFVDVVKWKMYKMQTIVRDKLRTESENKGYVCQNCEKQFSPLDVLSLVDMTDQLFHCDQCEHILVENDNAENVKGSQQTLTRLREQSQPIITLLKQTDSIVIPSTYIYKHAPGSRANGGNRDEFELAVAQDTGAGQGDIIVDLQMDNEAARRAKMQEAEQKRQQNALPVWHQQSTISGTSLINTGDNNHATDDHEEEDAFEEIRPMEMDADTEDYYAKYYESLSYNNNSSNGNGEAVEYNEPTETFEETNHQSGSGEEFEEDEDVPLVSVNGKMIPLNEVQEEDQRNMTTDEYKAYYEAWERWQNN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N2R3</accession>
    <name>A0A1C7N2R3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Carboxylic acid transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">JEN1</name>
        <name evidence="8" type="ORF">A0J61_09041</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000760">
        <property type="protein sequence ID" value="OBZ82909.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N2R3"/>
    <dbReference type="STRING" id="101091.A0A1C7N2R3"/>
    <dbReference type="InParanoid" id="A0A1C7N2R3"/>
    <dbReference type="OrthoDB" id="5296287at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046943">
        <property type="term" value="F:carboxylic acid transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd17316">
        <property type="entry name" value="MFS_SV2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23508">
        <property type="entry name" value="CARBOXYLIC ACID TRANSPORTER PROTEIN HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23508:SF10">
        <property type="entry name" value="CARBOXYLIC ACID TRANSPORTER PROTEIN HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00217">
        <property type="entry name" value="SUGAR_TRANSPORT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="132"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="156"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="190"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="218"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="274"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="311"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="339"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="447"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="65"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="476"/>
            <end position="505"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="495"/>
            <end position="505"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OBZ82909.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="505" mass="55859" checksum="78627A21EE44780F" modified="2016-11-30" version="1">MTDQEKTPTKVHVEQVEHFPSEQRDSPNEHKNIFVRFKDSIYTKPEKSPNPWHLLTNLTNTQRITFASAFFGWSLDAFDFFSVSLSATRIAETYGVQPSDVTSAITTTLMLRPIGALIFGALADKYGRRWPLLFDIVLFSLINMASGFAPNLQTFIALRAVFGIAMGGEWGLGASLALESLPIEARGLFSGIYQQGYACGYLLATLVNYAVVETDSSWRILFWVGAGFALLAVVIRLWVPESETFEKQKVARKILGRSLWTEVKLAVRNHWLRLIYMVILMAFMNFFSHGSQDLYPTFLLTQLEYTVTQQTVTGVIMNVGAICGGMIFGHLSNSFGRRFILALCAICAGAFIPLWIYAPNIHALQFGAFVMQFFVQGAWGVIPAHINELAPPSFRGLMPGLAYQLGNLISAASSQIEATIGEKYPIRNADGSYKTNSKGEPIADYGLTQAIFMGCVCAGLLIAAVVGKEERNRDFSQDLAEDQTSNHIAVSPEDVSAHKIEEGQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N2X8</accession>
    <name>A0A1C7N2X8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Serine/threonine-protein kinase ste20</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">stk-4_1</name>
        <name evidence="3" type="ORF">A0J61_08581</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000675">
        <property type="protein sequence ID" value="OBZ83368.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N2X8"/>
    <dbReference type="STRING" id="101091.A0A1C7N2X8"/>
    <dbReference type="InParanoid" id="A0A1C7N2X8"/>
    <dbReference type="OrthoDB" id="4062651at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044773">
        <property type="term" value="P:mitotic DNA damage checkpoint signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44167">
        <property type="entry name" value="OVARIAN-SPECIFIC SERINE/THREONINE-PROTEIN KINASE LOK-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44167:SF24">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE CHK2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="2">
        <location>
            <begin position="20"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="394"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="474"/>
            <end position="583"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="394"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="493"/>
            <end position="506"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="547"/>
            <end position="565"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ83368.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="583" mass="65194" checksum="304A35609D05DB90" modified="2016-11-30" version="1">MQQVNGVPVLSSDPSLLYIGLEEEPTWFSAQGGVYKCIERSSEKEVAIKKYLVEENQYEDMFVMPKELVENEIYSMTKCVHPNILKLFAVHLHEEFVYLVMPLYTGGSLQHYAFDHQLSLGQLVYVITAIVSGLAKVHSHGYIHRDMKCDNIFLDQKTNSIVIGDFGVVSISPVADSSIEEAGVVLFWSPELVLQKIVNHKIDIWALGIIKKRILSVGKPKYPQNLPDQLVDLLDCCLDPDPRKRSSAQQLLQHPFLKAYPPEPLFPTTELAPITLIEPERPFKCRLPLPSFSVDRSISAAIPVREKIASVIQKRQSMTDTNRSQGSRIPMLSVPKKLSQLAPSQPVSARFSALAPKSSFTGARTLLQKPQLTRSNTVPTRIEQPPMRQLRSPISLQSSTRSIQPSSYLTTDRKIERSRPKKEKVKRELPPKCSVYRKRLPAGESRTARLTMGVSTNARRQSYRQREEEVEEAIEMTPTLGRSARLLKPPKQRPQSFAPSHSTINHSLIPESIKSSTVKSKIRRQSVPVPSKTMDPKKKGDHNNGTSNSSNSSSSSSSSSSSSSNSKEDASSLKNSIKALRVH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N3H7</accession>
    <name>A0A1C7N3H7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">5-demethoxyubiquinone hydroxylase, mitochondrial</fullName>
            <shortName evidence="8">DMQ hydroxylase</shortName>
            <ecNumber evidence="8">1.14.99.60</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Ubiquinone biosynthesis monooxygenase COQ7</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">coq7</name>
        <name evidence="8" type="synonym">COQ7</name>
        <name evidence="9" type="ORF">A0J61_08252</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Catalyzes the hydroxylation of 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) during ubiquinone biosynthesis. Has also a structural role in the COQ enzyme complex, stabilizing other COQ polypeptides.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>a 5-methoxy-2-methyl-3-(all-trans-polyprenyl)benzene-1,4-diol + AH2 + O2 = a 3-demethylubiquinol + A + H2O</text>
            <dbReference type="Rhea" id="RHEA:50908"/>
            <dbReference type="Rhea" id="RHEA-COMP:10859"/>
            <dbReference type="Rhea" id="RHEA-COMP:10914"/>
            <dbReference type="ChEBI" id="CHEBI:13193"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:17499"/>
            <dbReference type="ChEBI" id="CHEBI:84167"/>
            <dbReference type="ChEBI" id="CHEBI:84422"/>
            <dbReference type="EC" id="1.14.99.60"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </cofactor>
        <text evidence="8">Binds 2 iron ions per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1 8">Cofactor biosynthesis; ubiquinone biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Component of a multi-subunit COQ enzyme complex, composed of at least COQ3, COQ4, COQ5, COQ6, COQ7 and COQ9.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Mitochondrion inner membrane</location>
            <topology evidence="8">Peripheral membrane protein</topology>
            <orientation evidence="8">Matrix side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the COQ7 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.14.99.60" evidence="8"/>
    <dbReference type="EMBL" id="LUGH01000619">
        <property type="protein sequence ID" value="OBZ83695.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="FunCoup" id="A0A1C7N3H7">
        <property type="interactions" value="228"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N3H7"/>
    <dbReference type="InParanoid" id="A0A1C7N3H7"/>
    <dbReference type="OrthoDB" id="275371at2759"/>
    <dbReference type="UniPathway" id="UPA00232"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031314">
        <property type="term" value="C:extrinsic component of mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008682">
        <property type="term" value="F:3-demethoxyubiquinol 3-hydroxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0160224">
        <property type="term" value="F:3-demethoxyubiquinone 3-hydroxylase (NADH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006744">
        <property type="term" value="P:ubiquinone biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01042">
        <property type="entry name" value="DMQH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01658">
        <property type="entry name" value="COQ7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009078">
        <property type="entry name" value="Ferritin-like_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011566">
        <property type="entry name" value="Ubq_synth_Coq7"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11237:SF4">
        <property type="entry name" value="5-DEMETHOXYUBIQUINONE HYDROXYLASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11237">
        <property type="entry name" value="COENZYME Q10 BIOSYNTHESIS PROTEIN 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03232">
        <property type="entry name" value="COQ7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47240">
        <property type="entry name" value="Ferritin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8" id="KW-0408">Iron</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="8" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="6 8" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="4 8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0830">Ubiquinone</keyword>
    <keyword evidence="2 8" id="KW-0831">Ubiquinone biosynthesis</keyword>
    <feature type="binding site" evidence="8">
        <location>
            <position position="55"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="86"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="86"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="89"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="138"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="176"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="176"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="179"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <label>2</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004749"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022688"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OBZ83695.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="215" mass="24192" checksum="EFAED3060D21D6DC" modified="2016-11-30" version="1">MLTQHLSLSLKRSMNRTLKRTLATYKSSPIVSQRSLTEEERQAIEPMIRVDQAGEVGAYYIYKGQIAVLGKDKALKPILQEMWDQEKLHLAKFDQLIGHHRVRPSMLRPVWEVAGYAVGFGTAMLGKEAAMACTEAVETVIGGHYDDQLRELVTFKDPNQELVDLSETVAKFRDEELEHHDIAVAHDAQAAPFHSVLXQVIMQGCKTAIWVASRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N3Z9</accession>
    <name>A0A1C7N3Z9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_08183</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000607">
        <property type="protein sequence ID" value="OBZ83767.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N3Z9"/>
    <dbReference type="InParanoid" id="A0A1C7N3Z9"/>
    <dbReference type="OrthoDB" id="2299019at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00646">
        <property type="entry name" value="F-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="1">
        <location>
            <begin position="1"/>
            <end position="49"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ83767.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="566" mass="64540" checksum="81C5984822786596" modified="2016-11-30" version="1">MTASNLPFEIQQIILSHLNSTAQIQYSLVSKHWRAAAKHVLFDTIYLPSGQKVDECVDLLLVSSPLGEFVKKLVFLTCASLNEAKQYSSLIHLTPNLKVLATEKSSNRLFQTAIQEVRSGHWKHLHSIGDLSIENDYDSVTEMGTEPFKSSVLDYYALASVLQDRLSAFVFDITSIDNSSVEPYCFQLPLYITRQTRFNALKDLICFSQGTTTIESLDDTLALCQNATEVKLSVHHFRTSKERWRQIEPNASVKSLSVFVTKFTEASLGYIYRKFSAVKQLTMHALDHSISNTDETIDPLEVPVDMKHQLAYYVHSTTTSDIWFYGINNSIELFLAFVSMQWPGEMQINLESNLFQLQHDSSKPKHSELHIDLDIGGLNVKQATLRDYLNQLDVLSIGPIDVRYYPLLAQCTRIRVLRMYYGNPSGYQGPTLAISRLILFSEDYNANFLKEFSASTPNLRHVNLVLCTFGKIEIDTPCVSYDSLCVENLGWIMQSSVCLLLIRSGIQSYYKTIENRLCEIGIDEFKGQAVKMDRAKVELICNDIKRLEIHWRVKDSGRVRILHDFY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N401</accession>
    <name>A0A1C7N401_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">G patch domain-containing protein 11</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">GPATCH11</name>
        <name evidence="3" type="ORF">A0J61_08152</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000602">
        <property type="protein sequence ID" value="OBZ83800.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N401"/>
    <dbReference type="STRING" id="101091.A0A1C7N401"/>
    <dbReference type="InParanoid" id="A0A1C7N401"/>
    <dbReference type="OrthoDB" id="786951at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000776">
        <property type="term" value="C:kinetochore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025239">
        <property type="entry name" value="DUF4187"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000467">
        <property type="entry name" value="G_patch_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039249">
        <property type="entry name" value="GPATCH11"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21032">
        <property type="entry name" value="G PATCH DOMAIN-CONTAINING PROTEIN 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21032:SF0">
        <property type="entry name" value="G PATCH DOMAIN-CONTAINING PROTEIN 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13821">
        <property type="entry name" value="DUF4187"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01585">
        <property type="entry name" value="G-patch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01173">
        <property type="entry name" value="DUF4187"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00443">
        <property type="entry name" value="G_patch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50174">
        <property type="entry name" value="G_PATCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="G-patch" evidence="2">
        <location>
            <begin position="66"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="18"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="95"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="182"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="19"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="182"/>
            <end position="200"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50174"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ83800.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="265" mass="31412" checksum="0E8C0C190CB791C1" modified="2016-11-30" version="1">MSDDEDYMSLKFLEEAQEFESKRKETTYSERRKKQIREQEKKGYIKPRAQLEAEERQKGLERSMDESNKGMKMLMKMGFKKGMSLGTDGIREPIKVDLKSGRGGIGMESELKKRAREQEEEEERERKRTAIDPEDFRSVMAQRMKESKLVRYLTAAVSICEKLDEENNVEFNILWILKPVQKEPEEQKADEEGQEEKQQKEEEEIDSSYPPEEVEELKSLTTEQQLRKILEYLRNNYLYCFWCSAKYENKSDLDDNCPGLEEDDH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N456</accession>
    <name>A0A1C7N456_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">FUZ/MON1/HPS1 first Longin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_08496</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000660">
        <property type="protein sequence ID" value="OBZ83456.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N456"/>
    <dbReference type="InParanoid" id="A0A1C7N456"/>
    <dbReference type="OrthoDB" id="10255234at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016192">
        <property type="term" value="P:vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043972">
        <property type="entry name" value="FUZ/MON1/HPS1_longin_1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19036">
        <property type="entry name" value="Fuz_longin_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FUZ/MON1/HPS1 first Longin" evidence="2">
        <location>
            <begin position="3"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="355"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="368"/>
            <end position="382"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF19036"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ83456.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="570" mass="65151" checksum="841B237556C26231" modified="2016-11-30" version="1">MIYFILNKLGSVIYQSEQHDLMTENNKIRYLPLLVIKDLIRANLHDVLEYVDTGQKLVVFKEQQNLLYVAYADKYPSLPVSVIQLHLKTMHQYLKFHYGPHWALQLQGNHPRRHKHTPSLRPSDIHTCLSQLPFTQRIHSIRSIESLCATEQVQLDDDLRTRLTESLAQCCQPFVYSPSKSPFFSLDTVDTWSRCFLFAREKLVVEASHQSNHAPDEFVYFLRLLVSHYLLEKHEIATPQHTLSQSIVSNTTSIFPSSPSSSSSSSLAYVYEANSSSAPFKMRGKSTSSATVVSSDSSLSYWHTQTPRMDIQRVPSNVLHHPVNSSSTIADILNMDEIGYSKPFLSSSVPSSHQGIPLISPTSSEHIASAPSSPTSRSRSQSFNLGDDEEEEGTIDSSSVKHLLTHLMKGEHGYFDQPDDVKLVRRWVNLDGHIYLANLILVYYSGLCAIVVCKDDPTPNKAMLRHTWKPKSSQVKQFKSQLKDCLQDFYDFLLTKEATHFTNLSFALTYPGLVHFIHFNQRMMTAPCLVDLNELDRHHELLHEVYNQYSTDPCPWVWPHQSHLKQLNWP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N4D1</accession>
    <name>A0A1C7N4D1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Methyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">A0J61_07983</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000577">
        <property type="protein sequence ID" value="OBZ83963.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N4D1"/>
    <dbReference type="STRING" id="101091.A0A1C7N4D1"/>
    <dbReference type="InParanoid" id="A0A1C7N4D1"/>
    <dbReference type="OrthoDB" id="10253390at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021829">
        <property type="entry name" value="DUF3419"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041698">
        <property type="entry name" value="Methyltransf_25"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47473">
        <property type="entry name" value="BTA1P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47473:SF1">
        <property type="entry name" value="METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11899">
        <property type="entry name" value="DUF3419"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13649">
        <property type="entry name" value="Methyltransf_25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008889480" description="Methyltransferase domain-containing protein" evidence="2">
        <location>
            <begin position="23"/>
            <end position="688"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="38"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="domain" description="Methyltransferase" evidence="3">
        <location>
            <begin position="135"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="688"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OBZ83963.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="688" mass="79518" checksum="09B87CE9DCD875C8" modified="2016-11-30" version="1" fragment="single">MSKLRQHLPLTLRLSLVPLSLATTYLAQLDLFVHDQKWVSASLYAVVGLTMVLLVAWDHLKVPVQFMYSCFFKRIGHHGNDQQSRLESFYQDQAKIYDHSRQSLLRGRKTMLKLCAAQLKEQIATGMMNKRPIWVDLGGGTGWNIETMHESFPVDQFEQVILVDLTPSLCQVARERFAQKGWKNVTVLCQDAATFELPGLNGQLEGQVGLVTVSYALSMMDHFYPVVDRIQSLLAPEGVVGVVDFYVSGRTNAPAEKWSPQQNRQCNWFTRHFWQAWFELDHIQLAPGRRDYLEYRFGTIKSLNRRNHFIIPYLIQMPYYVWLGCSPARQNELSGLMEITDDADSIASGNSSPSSFSLASRRRRSSFAYQNKQWRLDYNPALACHTQFRSYIYAFTWEDPRVDLEYLQLTKEDVMFVITSAGDNALEYALKAQPKRIHCIDMNPCQNHLLELKLAGIASLEYTDFWRMFGDGQHPHFSTLLHDVISPHLSSYAFQYWSHNKDRFSHKFYKTGYSGLALSILEWWIRMQGLGKDIDAMTSASTIEEQMAIWNSKIRPAIFSPMIQKVLHNPMFMWNALGVPINQMNMFLKECTTQDYIENTLDPIPSYSLFSHDQYFYYLCLKQRYSKDSCPSYLTRDGFETLKSSGALQSFRLHTQSILGALQSMSDGYLTRLVVMDHMDWFDPESCE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N4G2</accession>
    <name>A0A1C7N4G2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">rhizopuspepsin</fullName>
            <ecNumber evidence="4">3.4.23.21</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="primary">pep2</name>
        <name evidence="17" type="ORF">A0J61_08008</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Hydrolysis of proteins with broad specificity similar to that of pepsin A, preferring hydrophobic residues at P1 and P1'. Clots milk and activates trypsinogen. Does not cleave 4-Gln-|-His-5, but does cleave 10-His-|-Leu-11 and 12-Val-|-Glu-13 in B chain of insulin.</text>
            <dbReference type="EC" id="3.4.23.21"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Vacuole</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 14">Belongs to the peptidase A1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.23.21" evidence="4"/>
    <dbReference type="EMBL" id="LUGH01000580">
        <property type="protein sequence ID" value="OBZ83941.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N4G2"/>
    <dbReference type="FunCoup" id="A0A1C7N4G2">
        <property type="interactions" value="57"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N4G2"/>
    <dbReference type="InParanoid" id="A0A1C7N4G2"/>
    <dbReference type="OrthoDB" id="771136at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005773">
        <property type="term" value="C:vacuole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004190">
        <property type="term" value="F:aspartic-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.70.10:FF:000036">
        <property type="entry name" value="Vacuolar aspartic protease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.70.10:FF:000002">
        <property type="entry name" value="Vacuolar aspartic proteinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.70.10">
        <property type="entry name" value="Acid Proteases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001461">
        <property type="entry name" value="Aspartic_peptidase_A1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001969">
        <property type="entry name" value="Aspartic_peptidase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033121">
        <property type="entry name" value="PEPTIDASE_A1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021109">
        <property type="entry name" value="Peptidase_aspartic_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47966">
        <property type="entry name" value="BETA-SITE APP-CLEAVING ENZYME, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47966:SF51">
        <property type="entry name" value="BETA-SITE APP-CLEAVING ENZYME, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00026">
        <property type="entry name" value="Asp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00792">
        <property type="entry name" value="PEPSIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50630">
        <property type="entry name" value="Acid proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00141">
        <property type="entry name" value="ASP_PROTEASE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51767">
        <property type="entry name" value="PEPTIDASE_A1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 14" id="KW-0064">Aspartyl protease</keyword>
    <keyword evidence="10 13" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="11" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="9 14" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6 14 17" id="KW-0645">Protease</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 15" id="KW-0732">Signal</keyword>
    <keyword evidence="5" id="KW-0926">Vacuole</keyword>
    <feature type="signal peptide" evidence="15">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008889477" description="rhizopuspepsin" evidence="15">
        <location>
            <begin position="21"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase A1" evidence="16">
        <location>
            <begin position="87"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="active site" evidence="12">
        <location>
            <position position="105"/>
        </location>
    </feature>
    <feature type="active site" evidence="12">
        <location>
            <position position="291"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="13">
        <location>
            <begin position="118"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="13">
        <location>
            <begin position="325"/>
            <end position="358"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001130"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004116"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013205"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022554"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022750"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR601461-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR601461-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU000454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS51767"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="OBZ83941.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="402" mass="44524" checksum="4440CFC4BD3EE3A9" modified="2016-11-30" version="1">MKIFALSAIVATVFATVSEAALTRIPIKKIDESPAERLQRYTHTGEYLTQKYFGSRQKNGNVAPFQVKPDGSVEHGVPISNYMNAQYYGDIEIGTPPQTFSVVFDTGSSNLWVPSTHCNSIACFLHRRYDSSQSRTYAENGTEFAIQYGTGSLEGFISQDTLRVAGVQVENQGFAESVKEPGFTFAFAKFDGIFGLGYDTISVKRTVPPFYNMVNKDLIDEPLFSFWLNDVNKGGEDVGGELVFGGVDPDHYKGNITWSDIRRKGYWEIELENIKFGEEYVDLDPVGAAIDTGSSLIVAPTTIADLINHELGAEKNWAGQYVVDCSLIPSLPEFCFVFSGKNFCLKGEDYVLKVQDQCISGFMGMDIPEPAGPLWIVGDVFLRKFYSVYDLGNNRVGLAESK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N4H4</accession>
    <name>A0A1C7N4H4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">PRA1 family protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">A0J61_08019</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 5">Membrane</location>
            <topology evidence="1 5">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the PRA1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000582">
        <property type="protein sequence ID" value="OBZ83928.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N4H4"/>
    <dbReference type="FunCoup" id="A0A1C7N4H4">
        <property type="interactions" value="377"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N4H4"/>
    <dbReference type="InParanoid" id="A0A1C7N4H4"/>
    <dbReference type="OrthoDB" id="63113at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004895">
        <property type="entry name" value="Prenylated_rab_accept_PRA1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19317">
        <property type="entry name" value="PRENYLATED RAB ACCEPTOR 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19317:SF0">
        <property type="entry name" value="PRENYLATED RAB ACCEPTOR PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03208">
        <property type="entry name" value="PRA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="73"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="118"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="144"/>
            <end position="163"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU363107"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OBZ83928.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="176" mass="19498" checksum="9B146482A16298F0" modified="2016-11-30" version="1">MSSPLLSTNTAEAIGNVASDAGRSFFQRFREQRLSNLRPLGEFLDKNRISFTANFGTITKRWNYNLQYFSANYLLIVLLLSIYAIITSWWLVFTIAFVFGGFYFISRLNGPLEFAGQSIPASTLYATYIISTIILLLFSGATGAIFWIIGAAAVIILGHAALLEEGIEGDFADEQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N4K3</accession>
    <name>A0A1C7N4K3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Ankyrin repeat domain-containing protein 16</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">ANKRD16</name>
        <name evidence="4" type="ORF">A0J61_07886</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000561">
        <property type="protein sequence ID" value="OBZ84065.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N4K3"/>
    <dbReference type="STRING" id="101091.A0A1C7N4K3"/>
    <dbReference type="InParanoid" id="A0A1C7N4K3"/>
    <dbReference type="OrthoDB" id="539213at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24198">
        <property type="entry name" value="ANKYRIN REPEAT AND PROTEIN KINASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24198:SF165">
        <property type="entry name" value="ANKYRIN REPEAT-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="31"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="121"/>
            <end position="153"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OBZ84065.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="322" mass="35916" checksum="D876E3ABC957B7F1" modified="2016-11-30" version="1">MQKYIKAIESENISKVDKNELKQVLSEKDEHGDTLLHFASRVHNLPAIRLLVDLGADPEAMNEHGRRPIHEAIDSVECLSYLIKTCGVDTNAMKRGDWTPIMIAGKLLVESGALLKRTTRDGRTPLYLAVQEGHLEASKFLTDQYPDAITQATNSGRLAIQAAAALPSTDTAFEITNYLLSHATVPLSTLLSYRDNSGRNIVLDAVVAQNLPLLEYLLFKANANVDDADSLGRRMVHHAAMMGHLKVLKALNQWNTISDWNIVDNWDHWTPLMHAARQGHQQVVDYLINTIHADPTIKDKQQRTAKDIASLWQHTAIAELLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N5Z2</accession>
    <name>A0A1C7N5Z2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Serine/threonine-protein phosphatase T</fullName>
            <ecNumber evidence="5">3.1.3.16</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="primary">Ppp5c</name>
        <name evidence="18" type="ORF">A0J61_07397</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18 19">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">Protein phosphatase that specifically binds to and dephosphorylates the molecular chaperone Hsp90. Dephosphorylation positively regulates the Hsp90 chaperone machinery.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>O-phospho-L-seryl-[protein] + H2O = L-seryl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:20629"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="EC" id="3.1.3.16"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="12">
            <dbReference type="Rhea" id="RHEA:20630"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the PPP phosphatase family. PP-5 (PP-T) subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.16" evidence="5"/>
    <dbReference type="EMBL" id="LUGH01000497">
        <property type="protein sequence ID" value="OBZ84553.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N5Z2"/>
    <dbReference type="FunCoup" id="A0A1C7N5Z2">
        <property type="interactions" value="1099"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N5Z2"/>
    <dbReference type="InParanoid" id="A0A1C7N5Z2"/>
    <dbReference type="OrthoDB" id="445564at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004722">
        <property type="term" value="F:protein serine/threonine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd07417">
        <property type="entry name" value="MPP_PP5_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.21.10:FF:000039">
        <property type="entry name" value="Serine/threonine-protein phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041753">
        <property type="entry name" value="PP5_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013235">
        <property type="entry name" value="PPP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051134">
        <property type="entry name" value="PPP_phosphatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006186">
        <property type="entry name" value="Ser/Thr-sp_prot-phosphatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45668">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN PHOSPHATASE 5-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45668:SF5">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN PHOSPHATASE 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08321">
        <property type="entry name" value="PPP5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13414">
        <property type="entry name" value="TPR_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF033096">
        <property type="entry name" value="PPPtase_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00114">
        <property type="entry name" value="STPHPHTASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00156">
        <property type="entry name" value="PP2Ac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="Metallo-dependent phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-0464">Manganese</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-0539">Nucleus</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0677">Repeat</keyword>
    <keyword evidence="9 16" id="KW-0802">TPR repeat</keyword>
    <feature type="repeat" description="TPR" evidence="16">
        <location>
            <begin position="9"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="domain" description="Serine/threonine specific protein phosphatases" evidence="17">
        <location>
            <begin position="187"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor/acceptor" evidence="15">
        <location>
            <position position="287"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00008786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00013081"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00047986"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00059747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00073946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PIRSR" id="PIRSR033096-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="SMART" id="SM00156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="OBZ84553.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="483" mass="54946" checksum="A173424872E0B254" modified="2016-11-30" version="1">MSEELKAKAEEIKNQANVFFKEKQFPAAVEKYSEAIELNPQVASYYTNRAFCHLKLENYGYSIADANKALEIDPTFTKANYRRASANMALGNFKEALKDLRVVSKRAPSDKDARAKFDECAKIVRRMEFEKAIEHNDQKRSVAENLDIDSIVVDDKYDGPRIDEETKMIDRTFVENMIDHFKAQKKIHKKYAFMILLAIRNYMYEAPSLIDVTIPEHGQLTVCGDVHGQFYDFINIFQINGYPSEDHAYLFNGDFVDRGSFSVEVILTLFAYKWLYPNRLFLARGNHETDNMNKVYGFEGEVKAKFSEMMFNLFSETFNALPLAHVIQNKIFVTHGGLFSRDNVTLDEIRKIDRIGQGQPGSEGLMCELLWSDPQPQLGRSPSKRGVGIQFGPDVTQNFLETNGLDMVIRSHEVKAEGYVKDHQGKCVTVFSAPNYCDTVGNKGALINITPDLKIDYVTFEAVPHPTVKPMQYASQFSGLLGM</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N620</accession>
    <name>A0A1C7N620_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Branched-chain-amino-acid aminotransferase</fullName>
            <ecNumber evidence="11">2.6.1.42</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">BAT2</name>
        <name evidence="12" type="ORF">A0J61_07387</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>L-isoleucine + 2-oxoglutarate = (S)-3-methyl-2-oxopentanoate + L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:24801"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:35146"/>
            <dbReference type="ChEBI" id="CHEBI:58045"/>
            <dbReference type="EC" id="2.6.1.42"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>L-leucine + 2-oxoglutarate = 4-methyl-2-oxopentanoate + L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:18321"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:17865"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:57427"/>
            <dbReference type="EC" id="2.6.1.42"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>L-valine + 2-oxoglutarate = 3-methyl-2-oxobutanoate + L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:24813"/>
            <dbReference type="ChEBI" id="CHEBI:11851"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:57762"/>
            <dbReference type="EC" id="2.6.1.42"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 10">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.6.1.42" evidence="11"/>
    <dbReference type="EMBL" id="LUGH01000495">
        <property type="protein sequence ID" value="OBZ84572.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N620"/>
    <dbReference type="FunCoup" id="A0A1C7N620">
        <property type="interactions" value="412"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N620"/>
    <dbReference type="InParanoid" id="A0A1C7N620"/>
    <dbReference type="OrthoDB" id="1732691at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052656">
        <property type="term" value="F:L-isoleucine-2-oxoglutarate transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052654">
        <property type="term" value="F:L-leucine-2-oxoglutarate transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052655">
        <property type="term" value="F:L-valine-2-oxoglutarate transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901705">
        <property type="term" value="P:L-isoleucine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009098">
        <property type="term" value="P:L-leucine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009099">
        <property type="term" value="P:L-valine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd01557">
        <property type="entry name" value="BCAT_beta_family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.10.10:FF:000004">
        <property type="entry name" value="Branched-chain-amino-acid aminotransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.470.10:FF:000005">
        <property type="entry name" value="Branched-chain-amino-acid aminotransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.470.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.10.10">
        <property type="entry name" value="D-amino Acid Aminotransferase, subunit A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001544">
        <property type="entry name" value="Aminotrans_IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018300">
        <property type="entry name" value="Aminotrans_IV_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036038">
        <property type="entry name" value="Aminotransferase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005786">
        <property type="entry name" value="B_amino_transII"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043132">
        <property type="entry name" value="BCAT-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043131">
        <property type="entry name" value="BCAT-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033939">
        <property type="entry name" value="BCAT_family"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01123">
        <property type="entry name" value="ilvE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF009897">
        <property type="entry name" value="PRK13357.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11825:SF44">
        <property type="entry name" value="BRANCHED-CHAIN-AMINO-ACID AMINOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11825">
        <property type="entry name" value="SUBGROUP IIII AMINOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01063">
        <property type="entry name" value="Aminotran_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006468">
        <property type="entry name" value="BCAT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56752">
        <property type="entry name" value="D-aminoacid aminotransferase-like PLP-dependent enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00770">
        <property type="entry name" value="AA_TRANSFER_CLASS_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 11" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="3 11 12" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="7 11" id="KW-0100">Branched-chain amino acid biosynthesis</keyword>
    <keyword evidence="6 10" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 11 12" id="KW-0808">Transferase</keyword>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="8">
        <location>
            <position position="220"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009320"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR006468-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU004106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU004516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU004517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="OBZ84572.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="389" mass="43481" checksum="A824BA9C4CF33A0B" modified="2016-11-30" version="1">MFTFKSISLKNQLVAQSKRFYSELSASKLKLSKADSLKPLVANNELVFGHTFTDHMITADWNEKEGWAAPEVRPYENLSLAPSAVVFHYASECFEGMKAYKDKQGKIRLFRPDMNMARMNRSTSRIALPEFNGDELIKIIGEYLKVDERWIPTEKGYSLYLRPTMIGTQEALGVNPPTKAKLFVIGCPVGPYYKTGFNAVRLLATTEYVRAWPRGTGAAKIGGNYAPGLLPQRLAAKKGYQQNLWLFGDDHQLTEVGTMNLFILMKNDDGDLELVTPPLDGAILPGVTRDSIIGLAKEWNEFKVNERNMTMPELRDLAKSGRVVEMFGAGTACIVSPIKEIGYMGEDIKIPLDPKDPNSQAGPYTRRFNDAISAIQYGEVDHPWSVVVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N6B7</accession>
    <name>A0A1C7N6B7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Large ribosomal subunit protein uL5m</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">mrpl7</name>
        <name evidence="7" type="ORF">A0J61_07238</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uL5 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000479">
        <property type="protein sequence ID" value="OBZ84705.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N6B7"/>
    <dbReference type="FunCoup" id="A0A1C7N6B7">
        <property type="interactions" value="267"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N6B7"/>
    <dbReference type="InParanoid" id="A0A1C7N6B7"/>
    <dbReference type="OrthoDB" id="539541at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1440.10:FF:000001">
        <property type="entry name" value="50S ribosomal protein L5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1440.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002132">
        <property type="entry name" value="Ribosomal_uL5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031309">
        <property type="entry name" value="Ribosomal_uL5_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022803">
        <property type="entry name" value="Ribosomal_uL5_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031310">
        <property type="entry name" value="Ribosomal_uL5_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11994">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L11-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00281">
        <property type="entry name" value="Ribosomal_L5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00673">
        <property type="entry name" value="Ribosomal_L5_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55282">
        <property type="entry name" value="RL5-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 7" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Large ribosomal subunit protein uL5 N-terminal" evidence="5">
        <location>
            <begin position="115"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="domain" description="Large ribosomal subunit protein uL5 C-terminal" evidence="6">
        <location>
            <begin position="171"/>
            <end position="268"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00040368"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00673"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OBZ84705.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="272" mass="30113" checksum="687D11BBDC0B4D47" modified="2016-11-30" version="1">MASLLRTVCRQSLSRPFAVRSFSATATPASSHGLLRLKEYYDSTLSEDLMVLGYDHTRVAPTVSRYPDIEAKIAKALEATEELVKEEVKAPEVVRTRKGGKPVKPIQPLKSPRVIPSLDKITLHAMIKDSIHNKSNLLSAFMAFQSITGVRPEVVRARNSVANWKLREGMPVGVKVTLRGEEMYQFMDKLVEIVLPRLKEWPGLSMTAGDGNGNIALGFPPSALALFPEIEGSFDVYPKMTGFDVIFNTTAYTNTDGRLLLSAFSVPFKNKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-06-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N6H4</accession>
    <name>A0A1C7N6H4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_07229</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000477">
        <property type="protein sequence ID" value="OBZ84732.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N6H4"/>
    <dbReference type="InParanoid" id="A0A1C7N6H4"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008889509" evidence="1">
        <location>
            <begin position="21"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="42"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ84732.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="42" mass="4392" checksum="0AE49D0F78A87D5A" modified="2016-11-30" version="1" fragment="single">MRFITVSIVLAAAFIACSSAASIHQRDISDLDLLDDILGGDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N6P3</accession>
    <name>A0A1C7N6P3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_08970</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000745">
        <property type="protein sequence ID" value="OBZ82984.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N6P3"/>
    <dbReference type="InParanoid" id="A0A1C7N6P3"/>
    <dbReference type="OrthoDB" id="2363105at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="78"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="135"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="151"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ82984.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="151" mass="17357" checksum="A8AC590F19CDA2CC" modified="2016-11-30" version="1" fragment="single">MTHQIGNLNTSFSSSYCQQPFNSMPRTSSKRRMDEDDNDTGYQQVITNKYSLEIVIYFCLQPSTSAFTTKRHFDLNTQFSPEEPKQEPLPAITYASPDYRPPPPTETPLWLQPMPSNANSPMTEDGYSEDDNVLLTPSLQKFQQQQDDKTY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N7C5</accession>
    <name>A0A1C7N7C5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">SWI5-dependent HO expression protein 3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_06947</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000444">
        <property type="protein sequence ID" value="OBZ85002.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N7C5"/>
    <dbReference type="InParanoid" id="A0A1C7N7C5"/>
    <dbReference type="OrthoDB" id="2277294at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="56"/>
            <end position="112"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ85002.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="227" mass="26375" checksum="674319BC87D9BB7E" modified="2016-11-30" version="1">MIQSKRPLPPTPGTNTKYKNDNTELLLDKHHGSLTDGERKWYNDIHKSIEQKDSIIANLKTVASEWKKKANEYETAYKETKRLFEEREKFLMKQHEAEIEATTKIQAEQLNESHELILQLEKENMFLRSQLNQFNYLEQSSIQTQSANLNNDMYNQICHTAKRDSEIVNMHTPLSKENSNDLLQRINDMVIIVEGTLHRFKDREGIHSKASFVSLNATPDASNEQAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N8W0</accession>
    <name>A0A1C7N8W0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_06374</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000382">
        <property type="protein sequence ID" value="OBZ85572.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N8W0"/>
    <dbReference type="STRING" id="101091.A0A1C7N8W0"/>
    <dbReference type="InParanoid" id="A0A1C7N8W0"/>
    <dbReference type="OrthoDB" id="337486at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043625">
        <property type="term" value="C:delta DNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003887">
        <property type="term" value="F:DNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000731">
        <property type="term" value="P:DNA synthesis involved in DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006261">
        <property type="term" value="P:DNA-templated DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007218">
        <property type="entry name" value="DNA_pol_delta_4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14303">
        <property type="entry name" value="DNA POLYMERASE DELTA SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14303:SF0">
        <property type="entry name" value="DNA POLYMERASE DELTA SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04081">
        <property type="entry name" value="DNA_pol_delta_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ85572.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="110" mass="13072" checksum="B69008982B3CFA02" modified="2016-11-30" version="1">MPPTKQSPIRFTRARRYTNLQKQQLDPAVIQIGREHTDHLDRIEDILKAFDLNLAYGPCVETSIYLRNLYVYMKERAHALGLNPPRIVKEILKDQTQKYNHSLFDEYRMI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N984</accession>
    <name>A0A1C7N984_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 7">5-formyltetrahydrofolate cyclo-ligase</fullName>
            <ecNumber evidence="5 7">6.3.3.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">MTHFS</name>
        <name evidence="8" type="ORF">A0J61_06305</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="4 7">
            <text>(6S)-5-formyl-5,6,7,8-tetrahydrofolate + ATP = (6R)-5,10-methenyltetrahydrofolate + ADP + phosphate</text>
            <dbReference type="Rhea" id="RHEA:10488"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57455"/>
            <dbReference type="ChEBI" id="CHEBI:57457"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.3.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.3.2" evidence="5 7"/>
    <dbReference type="EMBL" id="LUGH01000374">
        <property type="protein sequence ID" value="OBZ85650.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N984"/>
    <dbReference type="FunCoup" id="A0A1C7N984">
        <property type="interactions" value="223"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N984"/>
    <dbReference type="InParanoid" id="A0A1C7N984"/>
    <dbReference type="OrthoDB" id="2015992at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030272">
        <property type="term" value="F:5-formyltetrahydrofolate cyclo-ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009396">
        <property type="term" value="P:folic acid-containing compound biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035999">
        <property type="term" value="P:tetrahydrofolate interconversion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.10420:FF:000007">
        <property type="entry name" value="5-formyltetrahydrofolate cyclo-ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10420">
        <property type="entry name" value="NagB/RpiA/CoA transferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002698">
        <property type="entry name" value="FTHF_cligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024185">
        <property type="entry name" value="FTHF_cligase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037171">
        <property type="entry name" value="NagB/RpiA_transferase-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02727">
        <property type="entry name" value="MTHFS_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23407:SF1">
        <property type="entry name" value="5-FORMYLTETRAHYDROFOLATE CYCLO-LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23407">
        <property type="entry name" value="ATPASE INHIBITOR/5-FORMYLTETRAHYDROFOLATE CYCLO-LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01812">
        <property type="entry name" value="5-FTHF_cyc-lig"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006806">
        <property type="entry name" value="FTHF_cligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100950">
        <property type="entry name" value="NagB/RpiA/CoA transferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0436">Ligase</keyword>
    <keyword evidence="7" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2 6 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="9"/>
            <end position="13"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="55"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="61"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="145"/>
            <end position="153"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010638"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00036539"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR006806-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU361279"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OBZ85650.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="208" mass="24096" checksum="3E510A66E5CB4147" modified="2016-11-30" version="1">MNQTIVTLKKQLRKDMAKKLKELSAAEIQNQSHLVFKRLQQLDHFKNSKNISVYISMPSGEIMTKDIIRYILNSDKRCYIPRCHKNTMDMVRITTIEDFESLPNNKWNIPEPPLDQPRQNALEQGSDGLDLILVPGVAFDRNRNRIGHGKGYYDRYIRQCKLWAEQNQLPPPKTVALSLEEQIVEPGRIPLEDTDQTLDTVLTCTTIY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-06-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N9B5</accession>
    <name>A0A1C7N9B5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_06724</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000420">
        <property type="protein sequence ID" value="OBZ85229.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N9B5"/>
    <dbReference type="InParanoid" id="A0A1C7N9B5"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ85229.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="66" mass="7761" checksum="2F1717F619921662" modified="2016-11-30" version="1">MFQTSNENWDVFINQHLFPFLESFYLLDEKLSYRKPFDIISCATITSGSEQVVTRGCRPTHRSDDQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N9P6</accession>
    <name>A0A1C7N9P6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Restriction of telomere capping protein 5</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">RTC5</name>
        <name evidence="8" type="ORF">A0J61_06173</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">May be involved in a process influencing telomere capping.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the RTC5 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000360">
        <property type="protein sequence ID" value="OBZ85780.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N9P6"/>
    <dbReference type="STRING" id="101091.A0A1C7N9P6"/>
    <dbReference type="InParanoid" id="A0A1C7N9P6"/>
    <dbReference type="OrthoDB" id="289228at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006979">
        <property type="term" value="P:response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006571">
        <property type="entry name" value="TLDc_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23354">
        <property type="entry name" value="NUCLEOLAR PROTEIN 7/ESTROGEN RECEPTOR COACTIVATOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23354:SF130">
        <property type="entry name" value="RESTRICTION OF TELOMERE CAPPING PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07534">
        <property type="entry name" value="TLD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00584">
        <property type="entry name" value="TLDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51886">
        <property type="entry name" value="TLDC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TLDc" evidence="7">
        <location>
            <begin position="275"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="14"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006731"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00015163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51886"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OBZ85780.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="515" mass="58681" checksum="7E8C23336C224C42" modified="2016-11-30" version="1">MGQSSTKPEVLPQPSISSSTANSFRPKKHLSRVELVSLQHTFKDLKSTFKDDFECIEAKQFLARSYPACTVAGPVPLSFNAFITAFVLLTGRLDEPSHPLSEKMLFKSLSILPTPESTPPSPPLVSNEELNQDTVKSTSSKGLSLAELGVDFNDLDLDVKDTDDSKASDKILSRDLVEILVLLLWLGETDKQNSHDFATFSKIANGIVSTMQTSKDEPCVTYKSFCHWKDRFAPHWLKPIQSMVIRSFGYYDPIPTSKQPRLLPEDTVPSPDTTDILSPLHTTLLSWPIAEPILITKQWTRLYSADKDGFSMNRFESHVFKYPGPTLLVIQANAPDRNLLIGAYIAQPWKHSKQFWGNDQCFLFELEPDLDVYRPVINRRTKEAQNDHFIYYHHEFGIGLGATTRTTKHDFVIHLDNTLQKGGYQHEAYPPLPSFMSAIKSQKQVEFSYLFETDNIEVFGLGNEKDRERQAREWKFERQEADRRAHLNIRQADGDLDKELLKMAGIIDEDNRQDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NA66</accession>
    <name>A0A1C7NA66_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Translation initiation factor IF-2, mitochondrial</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">MTIF2</name>
        <name evidence="13" type="ORF">A0J61_05935</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000336">
        <property type="protein sequence ID" value="OBZ86022.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NA66"/>
    <dbReference type="FunCoup" id="A0A1C7NA66">
        <property type="interactions" value="548"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NA66"/>
    <dbReference type="InParanoid" id="A0A1C7NA66"/>
    <dbReference type="OrthoDB" id="361630at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01887">
        <property type="entry name" value="IF2_eIF5B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03702">
        <property type="entry name" value="IF2_mtIF2_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03692">
        <property type="entry name" value="mtIF2_IVc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.30.10:FF:000007">
        <property type="entry name" value="Translation initiation factor IF-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.30.10:FF:000008">
        <property type="entry name" value="Translation initiation factor IF-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.10050:FF:000001">
        <property type="entry name" value="Translation initiation factor IF-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000019">
        <property type="entry name" value="Translation initiation factor IF-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.10">
        <property type="entry name" value="Translation factors"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10050">
        <property type="entry name" value="Translation initiation factor IF- 2, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00100_B">
        <property type="entry name" value="IF_2_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053905">
        <property type="entry name" value="EF-G-like_DII"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044145">
        <property type="entry name" value="IF2_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000795">
        <property type="entry name" value="T_Tr_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000178">
        <property type="entry name" value="TF_IF2_bacterial-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015760">
        <property type="entry name" value="TIF_IF2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023115">
        <property type="entry name" value="TIF_IF2_dom3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036925">
        <property type="entry name" value="TIF_IF2_dom3_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43381:SF20">
        <property type="entry name" value="TRANSLATION INITIATION FACTOR IF-2, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43381">
        <property type="entry name" value="TRANSLATION INITIATION FACTOR IF-2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22042">
        <property type="entry name" value="EF-G_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00009">
        <property type="entry name" value="GTP_EFTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11987">
        <property type="entry name" value="IF-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52156">
        <property type="entry name" value="Initiation factor IF2/eIF5b, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="Translation proteins"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51722">
        <property type="entry name" value="G_TR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="3 13" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="7" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="Tr-type G" evidence="12">
        <location>
            <begin position="255"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="37"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="77"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="113"/>
            <end position="144"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007733"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00025162"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00044200"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="OBZ86022.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="807" mass="90119" checksum="6038B62CB51CB95A" modified="2016-11-30" version="1">MSATRQLLWLLNQYKPYGVHQVQRSWMGRPMFFQTTSRLSNRLGKPTEGTAGSKKIKRTDWQRPDQVGNNPLKKVAPKRDWSRPVDQHVEKHAGETPKQHERHVNKFAKQPPKKSETQAQKRERKKREEELAALARQEEKERSQIEMRKAKQKAKEKEASNQMKDVFIPEIINVANLSRVLGIRLAWRSYSVSVEHLVRTMEELEMGNTSHDRMLNAEESSLIAMQLDMNPIVDSRQSLDLYPRSAPVDPSQLVDRPPIVTIMGHVDHGKTTLLDTLRKTSVAAGEAGGITQHIGAFSVKLPSNKTITFLDTPGHAAFSAMRQRGAQVTDIVVLVVAADDGVMPQTQEAIRHAQAANVPIVVAINKCDKPGVDPSRVKQELTRYNVHLEEIGGDVPCVEVSGLTGKNLDQLEETIITLSEILELKAERNNGAEGVVIESQIEKGRGNVATVLVQRGTLTPGSVIVAGRTWCKVRSMTDHQGKIVKAATPGMPVKVIGWKDVPSAGDEMLTAKDEGLAKTVVDNRVARHQREQQLRDLEVINDKRKIQREQLEQERMAEKAYKKEMYMYQRGLIDTLPDSLNKRLYALQEQNEEEKPEDNMLELRAVVKGDVSGTVEAVVDCLAGLQNKQIRVKVVHSSVGNITESDVQLAAACEGQVIGFNVRADKRIQAEAAKIGVPVKSYSIIYKLLEDVKDELSNMLPPIVSTQVVGEAALLQVFDINTKGRETRPVAGCRVTNGSIQRNGRVRIVRDKETIWEGELDTLRQVKKDITEAKKGLECGMSFEGFSDFKPGDVIQCVQTIETKQKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NA79</accession>
    <name>A0A1C7NA79_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">DNA mismatch repair protein MLH1</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13">DNA mismatch repair protein Mlh1</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="15">MutL protein homolog 1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="17" type="primary">MLH1</name>
        <name evidence="17" type="ORF">A0J61_06363</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Chromosome</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the DNA mismatch repair MutL/HexB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000381">
        <property type="protein sequence ID" value="OBZ85589.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NA79"/>
    <dbReference type="FunCoup" id="A0A1C7NA79">
        <property type="interactions" value="440"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NA79"/>
    <dbReference type="InParanoid" id="A0A1C7NA79"/>
    <dbReference type="OrthoDB" id="10263226at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005694">
        <property type="term" value="C:chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032389">
        <property type="term" value="C:MutLalpha complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031981">
        <property type="term" value="C:nuclear lumen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140664">
        <property type="term" value="F:ATP-dependent DNA damage sensor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030983">
        <property type="term" value="F:mismatched DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006298">
        <property type="term" value="P:mismatch repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd16926">
        <property type="entry name" value="HATPase_MutL-MLH-PMS-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03483">
        <property type="entry name" value="MutL_Trans_MLH1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.230.10:FF:000014">
        <property type="entry name" value="DNA mismatch repair protein Mlh1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.565.10:FF:000034">
        <property type="entry name" value="DNA mismatch repair protein mlh1, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="entry name" value="Histidine kinase-like ATPase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014762">
        <property type="entry name" value="DNA_mismatch_repair_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013507">
        <property type="entry name" value="DNA_mismatch_S5_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032189">
        <property type="entry name" value="Mlh1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002099">
        <property type="entry name" value="MutL/Mlh/PMS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038973">
        <property type="entry name" value="MutL/Mlh/Pms-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_Su5_D2-typ_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribsml_uS5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00585">
        <property type="entry name" value="mutl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10073">
        <property type="entry name" value="DNA MISMATCH REPAIR PROTEIN MLH, PMS, MUTL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10073:SF12">
        <property type="entry name" value="DNA MISMATCH REPAIR PROTEIN MLH1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01119">
        <property type="entry name" value="DNA_mis_repair"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13589">
        <property type="entry name" value="HATPase_c_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16413">
        <property type="entry name" value="Mlh1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01340">
        <property type="entry name" value="DNA_mis_repair"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="Ribosomal protein S5 domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00058">
        <property type="entry name" value="DNA_MISMATCH_REPAIR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0007">Acetylation</keyword>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="12" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="4" id="KW-0158">Chromosome</keyword>
    <keyword evidence="7" id="KW-0227">DNA damage</keyword>
    <keyword evidence="10" id="KW-0234">DNA repair</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA mismatch repair protein S5" evidence="16">
        <location>
            <begin position="222"/>
            <end position="341"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022990"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00071080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00072852"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00082865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="SMART" id="SM01340"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="OBZ85589.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="667" mass="74661" checksum="4232DA27AA3DEBFC" modified="2016-11-30" version="1">MTTIPSIKKLDQAVVNRIAAGEVIQRPANALKELIENSLDAGSTQIQILIKDGGLKLLQIQDNGHGIRKEDMRIVCERFTTSKLSKFEDLMGISTYGFRGEALASISHVAHVTITTKTAESPCAYRALYSDGQLTPARPGASAEPKACAGNNGTQITAEDLFYNVPTRRKALKSPSDEYNRILDIVSRYAVHNAGISFTCRKQGATMADVQTSTGATVVDTIRQLYGSSVASELLPVEQSLETLDVTVKGQITNANYSMKRMTLLLFINHRAVESSSIKRAIESVYSALLPKGGHPFVYLSLQMDPKNVDVNVHPTKKEVHFLHEERIVQALGDVFQKVLENANTSRTFYTQALLPGVSDPTVEPQEASFNHRQSVPEYKYVRTDSRVTTLDAFVHSKSNPSCASLAGDKDETHSTEVDTVSKPRVEVRLTSVLQLRKEIKKAENQGLTYILSNHTFIGCVDDALALIQHEQNIYIINYSAASEELMYQIVLNEFCNMGHIRFTEPISIRDCLRIAIDHEAQQGNLPATIKTPEEMIELITSMLISRAEMLQEYFSLTLSPEGQLVAIPMLIRDYIPCMEKLPLFLLRLGTEVDWEHEKECFHTLSREIAIFYSAEPPMTDKEGYLWKVQHLVFPCFKTRFSAPTKLKTFVTQLANLADLYKIFERC</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NAD9</accession>
    <name>A0A1C7NAD9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">P-type Cu(+) transporter</fullName>
            <ecNumber evidence="3">7.2.2.8</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="17">Cu(2+)-ATPase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="20" type="primary">Atp7b</name>
        <name evidence="20" type="ORF">A0J61_05965</name>
    </gene>
    <organism evidence="20 21">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="20 21" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="20 21">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="18">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 18">Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="20">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="7.2.2.8" evidence="3"/>
    <dbReference type="EMBL" id="LUGH01000340">
        <property type="protein sequence ID" value="OBZ85980.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NAD9"/>
    <dbReference type="InParanoid" id="A0A1C7NAD9"/>
    <dbReference type="OrthoDB" id="432719at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005507">
        <property type="term" value="F:copper ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043682">
        <property type="term" value="F:P-type divalent copper transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140581">
        <property type="term" value="F:P-type monovalent copper transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055070">
        <property type="term" value="P:copper ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00371">
        <property type="entry name" value="HMA"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.100:FF:000001">
        <property type="entry name" value="ATPase copper transporting beta"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="2.70.150.10:FF:000002">
        <property type="entry name" value="Copper-transporting ATPase 1, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.100">
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.150.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023299">
        <property type="entry name" value="ATPase_P-typ_cyto_dom_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018303">
        <property type="entry name" value="ATPase_P-typ_P_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023298">
        <property type="entry name" value="ATPase_P-typ_TM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008250">
        <property type="entry name" value="ATPase_P-typ_transduc_dom_A_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059000">
        <property type="entry name" value="ATPase_P-type_domA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017969">
        <property type="entry name" value="Heavy-metal-associated_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006122">
        <property type="entry name" value="HMA_Cu_ion-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006121">
        <property type="entry name" value="HMA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036163">
        <property type="entry name" value="HMA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027256">
        <property type="entry name" value="P-typ_ATPase_IB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001757">
        <property type="entry name" value="P_typ_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044492">
        <property type="entry name" value="P_typ_ATPase_HD_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01525">
        <property type="entry name" value="ATPase-IB_hvy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01494">
        <property type="entry name" value="ATPase_P-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00003">
        <property type="entry name" value="copper ion binding protein"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43520">
        <property type="entry name" value="ATP7, ISOFORM B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43520:SF8">
        <property type="entry name" value="P-TYPE CU(+) TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00122">
        <property type="entry name" value="E1-E2_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00403">
        <property type="entry name" value="HMA"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00702">
        <property type="entry name" value="Hydrolase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00119">
        <property type="entry name" value="CATATPASE"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG00002">
        <property type="entry name" value="C1.7:_P-type_atpase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00003">
        <property type="entry name" value="Haloacid_Dehalogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00027">
        <property type="entry name" value="p-type_atpase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81653">
        <property type="entry name" value="Calcium ATPase, transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81665">
        <property type="entry name" value="Calcium ATPase, transmembrane domain M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55008">
        <property type="entry name" value="HMA, heavy metal-associated domain"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81660">
        <property type="entry name" value="Metal cation-transporting ATPase, ATP-binding domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00154">
        <property type="entry name" value="ATPASE_E1_E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01047">
        <property type="entry name" value="HMA_1"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50846">
        <property type="entry name" value="HMA_2"/>
        <property type="match status" value="7"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 18" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="14" id="KW-0186">Copper</keyword>
    <keyword evidence="9" id="KW-0187">Copper transport</keyword>
    <keyword evidence="15" id="KW-0406">Ion transport</keyword>
    <keyword evidence="11" id="KW-0460">Magnesium</keyword>
    <keyword evidence="16 18" id="KW-0472">Membrane</keyword>
    <keyword evidence="6 18" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8 18" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0677">Repeat</keyword>
    <keyword evidence="12" id="KW-1278">Translocase</keyword>
    <keyword evidence="5 18" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="13 18" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="697"/>
            <end position="720"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="732"/>
            <end position="754"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="774"/>
            <end position="798"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="985"/>
            <end position="1004"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="1024"/>
            <end position="1044"/>
        </location>
    </feature>
    <feature type="domain" description="HMA" evidence="19">
        <location>
            <begin position="13"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="domain" description="HMA" evidence="19">
        <location>
            <begin position="105"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="domain" description="HMA" evidence="19">
        <location>
            <begin position="192"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="domain" description="HMA" evidence="19">
        <location>
            <begin position="305"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="domain" description="HMA" evidence="19">
        <location>
            <begin position="413"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="domain" description="HMA" evidence="19">
        <location>
            <begin position="502"/>
            <end position="570"/>
        </location>
    </feature>
    <feature type="domain" description="HMA" evidence="19">
        <location>
            <begin position="599"/>
            <end position="665"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="20">
        <location>
            <position position="1434"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022796"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00080126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="RuleBase" id="RU362081"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="PROSITE" id="PS50846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="OBZ85980.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="1434" mass="157246" checksum="DD80C1E6ED72F652" modified="2016-11-30" version="1" fragment="single">MPELIRDSSNFSYSIEIGIEGMTCNHCVNTIKKALEEYSGSVSGSVEVSLDQSKAILKYENTENNTENDLKDAFTELIENLGYEATSLILVRINQSDCHEAYEELQVKISVYGMTCSHCTNTVQKALQTFPFIDPESVCVSLEKEQATMVYHGSNYTSDKDEIKAKIEDLGYDVGNVTLNTELPELNDYEAKCMVLSISGMTCQHCTQTVSNALEELPGTITGSVDVSLEKKQARFSFEGSVIDAEVVKELIENLGYDLNGKPRIKQDSGRELSKSYTSQLSITMPNDNSVVQLNDNNCDDGGKRKVVMRVLGMTCKSCVASVTDALENEIPNVQPGSIHVNLQTEMAMFICTNPDIDFIHTVIEERGFDVENVQIIHNLIPPVVLLSRQQQQRQGSIVSLVSVESQTVSVPHKVRFQISGMTCASCVRTVEEGLRKLPGVNPSSVQVNLLTQTGSLSVYGSFLDEKSLVKAIKKMGYKASKVSFISELQASDIQTASNAIYKANMIIVGMFCANCVEKTYGALKKLLGIRSQSIQIDLESGKASFEFTGELITRQKIYQAILQIGFTAESIKIKKMANEFPSDNDSSSIRSQGTIQIVSTHLVVTGMTCSSCVANIERTMMKQNGVTSCQVNLLAKSAVIQHDPNVVGSRSLAQMIEQIGYKAELSADKQGDTILEQRESMRESMNKELAILKSRFLWSLLFAIPVVLISMIFMMALPASSPVHRAFMKQITHGLSIGDLILFLLATPVQFWLGKPFYTKAYKSLVYAHTANMETLVAMGTTVAYFASVASVVAAMVRKTAGAMSLNYFETSVLLITFIHFGKWLEALAKGKTAETITKLMDLQPEKAILIETQRDDVESSAARDGDGNFVDRIVSEREIESKDIQVGDILKINAGGRIPCDGKVWRGSSTADESMITGESIPVIKNKGDNVITATINLTAPIYVRAVRVGSDTTLSRIIQLVQDAQASPKAPIEQMADNISSIFVPIVILLALITFIVWEVLSIKNMYPDSWLPAGENKTLFSLMLAVTVLVIACPCGLGLASPTAVMVGTGVAAKYGVLIKGGGYALEMANRITTVAFDKTGTLTMGKPLVTHVWIDQSGPEKTKDNTAGQRITMWKILGCVSSASNHPLSKSIEKKSRYIIEQLLENPSISDIELLANDVIGSEQEEEEESDTSRPSKDINHFEGVMITNAQEIPGRGLLATITLSSDLSCNLAGRLQNVRALNVFLGNQEWMDENHARYQNSYQTRTCHNLLTDWQNLGQSIVMVSASPVSDNDREPSSADNHKEGCRNDCACDVCHCATSSLCCSASRTMMMAQLAIADIPRPEAMQLISELQERNIEVWMITGDNERTGSAVGKQLGINSDHVLAGVKPEQKADKIRNLQRRGIRSSEQQNHNFSKHYRRLRKHENAVVAMVGDGINDSPALAQADV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NAE1</accession>
    <name>A0A1C7NAE1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">UDP-N-acetylglucosamine transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">SLC35A3_1</name>
        <name evidence="7" type="ORF">A0J61_05874</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000331">
        <property type="protein sequence ID" value="OBZ86073.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NAE1"/>
    <dbReference type="FunCoup" id="A0A1C7NAE1">
        <property type="interactions" value="46"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NAE1"/>
    <dbReference type="InParanoid" id="A0A1C7NAE1"/>
    <dbReference type="OrthoDB" id="408493at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015165">
        <property type="term" value="F:pyrimidine nucleotide-sugar transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037185">
        <property type="entry name" value="EmrE-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007271">
        <property type="entry name" value="Nuc_sug_transpt"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00803">
        <property type="entry name" value="nst"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10231">
        <property type="entry name" value="NUCLEOTIDE-SUGAR TRANSMEMBRANE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04142">
        <property type="entry name" value="Nuc_sug_transp"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005799">
        <property type="entry name" value="UDP-gal_transpt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103481">
        <property type="entry name" value="Multidrug resistance efflux transporter EmrE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="13"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="121"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="173"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="242"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="273"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="202"/>
            <end position="224"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OBZ86073.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="343" mass="37681" checksum="92265EF0877C5056" modified="2016-11-30" version="1">MRYTRANVEEDKLYLASTAVVMSEVIKSFVCLVVLYFAPESRKRSLSKLTSLLNRELILNWRETAKLAIPAALYLVQNNLQYVAASNLDAATFQVTYQLKILTTAFFSVIILKRNLSKLKWIALAILTMGIALVVLPKSASTAFVAYITGNTMITDSTIEGTTSVPEGNQSNLHGFLAVLCACMLSGLAGVYFEKILKAPTPKPVPTEDDEEEIKRASVQDDDDDETTVSNQIWIRNIQMSFFSVLLGLVFVVMLQDGATIAERGFFVNYTPLTWTVIGIQALGGLIVALVVKYADNILKGFATSISIILSSIVSVWLFNFAFSGSFLLGAALVIYATYLYGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NAI7</accession>
    <name>A0A1C7NAI7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="16">DNA repair protein rad13</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="16" type="primary">rad13</name>
        <name evidence="16" type="ORF">A0J61_06303</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="12">Belongs to the XPG/RAD2 endonuclease family. GEN subfamily.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the XPG/RAD2 endonuclease family. XPG subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000374">
        <property type="protein sequence ID" value="OBZ85646.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NAI7"/>
    <dbReference type="FunCoup" id="A0A1C7NAI7">
        <property type="interactions" value="480"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NAI7"/>
    <dbReference type="InParanoid" id="A0A1C7NAI7"/>
    <dbReference type="OrthoDB" id="31113at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048256">
        <property type="term" value="F:flap endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006289">
        <property type="term" value="P:nucleotide-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd09904">
        <property type="entry name" value="H3TH_XPG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd09868">
        <property type="entry name" value="PIN_XPG_RAD2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.150.20:FF:000030">
        <property type="entry name" value="Flap endonuclease GEN-like 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1010:FF:000061">
        <property type="entry name" value="Single-stranded DNA endonuclease (Eurofung)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.20">
        <property type="entry name" value="5' to 3' exonuclease, C-terminal subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1010">
        <property type="entry name" value="5'-nuclease"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036279">
        <property type="entry name" value="5-3_exonuclease_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008918">
        <property type="entry name" value="HhH2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029060">
        <property type="entry name" value="PIN-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006086">
        <property type="entry name" value="XPG-I_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006084">
        <property type="entry name" value="XPG/Rad2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001044">
        <property type="entry name" value="XPG/Rad2_eukaryotes"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019974">
        <property type="entry name" value="XPG_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006085">
        <property type="entry name" value="XPG_DNA_repair_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16171">
        <property type="entry name" value="DNA REPAIR PROTEIN COMPLEMENTING XP-G CELLS-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16171:SF7">
        <property type="entry name" value="DNA REPAIR PROTEIN RAD2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00867">
        <property type="entry name" value="XPG_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00752">
        <property type="entry name" value="XPG_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00853">
        <property type="entry name" value="XPGRADSUPER"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00066">
        <property type="entry name" value="XRODRMPGMNTG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00279">
        <property type="entry name" value="HhH2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00484">
        <property type="entry name" value="XPGI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00485">
        <property type="entry name" value="XPGN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47807">
        <property type="entry name" value="5' to 3' exonuclease, C-terminal subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88723">
        <property type="entry name" value="PIN domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00841">
        <property type="entry name" value="XPG_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0227">DNA damage</keyword>
    <keyword evidence="10" id="KW-0234">DNA repair</keyword>
    <keyword evidence="6" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0540">Nuclease</keyword>
    <keyword evidence="11" id="KW-0539">Nucleus</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="XPG N-terminal" evidence="15">
        <location>
            <begin position="1"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="domain" description="XPG-I" evidence="14">
        <location>
            <begin position="849"/>
            <end position="918"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="602"/>
            <end position="636"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="702"/>
            <end position="731"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="611"/>
            <end position="636"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005283"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00038112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="SMART" id="SM00484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="SMART" id="SM00485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="OBZ85646.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="1115" mass="129233" checksum="144D770AFEABE58D" modified="2016-11-30" version="1">MGVQGLWTLVNPVARPTQLESLRRKRVAVDASIWIHQFMRTMRDKEGQALRNGHLLGFFRRICKLLFFDIKPVFVFDGGAPSLKRNTIRERRKRREGVRLNLKATARKILSAQVKSHVLVEQERKQRGMTSTDKDSIDYVYYDDLQQSTTKDVLRKKRKLDQFELPEIDKKANNSRLNKLDPRLATTDELREFVSEFNPSEMDIDSEAFSALPPEVQYEVIQDMMWKSRSTSWSRLDNMVRNSNTALDFSKQQIKLLKHRNTMTQRLQQASTMQNGASTVEPVRIASERGRQYVLYKNEDLDQGLGWKLPGLSAAQPVEIDVTPKPSTRSEPKLEIPLKHELSSSTSTVIEEPEDKVAAAMASNPKLAGLFDSLLSDNEEENDKFDKIDTSMKDDSADDQEPLFVSDRQHDTFANDTHDHIHNGNQEQQDDTALNQIISRIYEQDTRDSLEQYIEDKQDANYSILSLNSEDTYDLWLSRVPDAFVYLHSFNDEYKKMIRRAIEESTLESLSNDLEVVKSQLFKANEIDELTVEALQFQETFLESIKEWKQRQFLNQEPLDVYFSEEESEVAPLTTTKEHDASSDIHQQDNDIILDDDEEEEEIHFISTKDSPQKKENDTPKLADDTQDDTNHLHIDMDKSTLKVNKKTEHIVDDTSSEEDVDFEDIENLQLKQESMEEFKDQSEETIKCQQEDTKAYNEEDILSHNEHERQNTAKQEIKDGKEQETQKLDDNKLDAKEQERQHIYEDTITEHYISNAEDTPFKTETVPSEAIPVNDHGYNSEDELGESFRGEDDEFVRFVSDISSKKIEDIRSQLFYDMKELNKQKRKEMGNSDDVTDRMIQDIQELLKLFGIPYIVSPMEAEAQCAELERLSLVDGTVTDDSDVFLFGASRVYKNMFNQQKYVECFMSQDIEREMQLTRKNLIQLAFLLGSDYTDGIPGVGPVAAMEILAEFSNVDVEDSENEEPLEKPLERFRDWYLSHEDKTPFQKKFRKRHQALEIPDDFPNPVVKNAYYYPTVDNSSQQFEWGQPQLELLRTFLMEAFGWPEDKADQVLLPVLREMNKKKTTGEQSTIGSFFHVAGNVSSTTAGSTQKKHSSKRVQNIVDNWKKQKKARK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NAW5</accession>
    <name>A0A1C7NAW5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Histone deacetylase complex subunit SAP30L</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">sap30l</name>
        <name evidence="9" type="ORF">A0J61_05811</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SAP30 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000325">
        <property type="protein sequence ID" value="OBZ86140.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NAW5"/>
    <dbReference type="InParanoid" id="A0A1C7NAW5"/>
    <dbReference type="OrthoDB" id="510958at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000118">
        <property type="term" value="C:histone deacetylase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003712">
        <property type="term" value="F:transcription coregulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.160.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024145">
        <property type="entry name" value="His_deAcase_SAP30/SAP30L"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038291">
        <property type="entry name" value="SAP30_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025718">
        <property type="entry name" value="SAP30_Sin3-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13286:SF6">
        <property type="entry name" value="HISTONE DEACETYLASE COMPLEX SUBUNIT SAP30L-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13286">
        <property type="entry name" value="SAP30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13867">
        <property type="entry name" value="SAP30_Sin3_bdg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0678">Repressor</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="4" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Histone deacetylase complex subunit SAP30 Sin3 binding" evidence="8">
        <location>
            <begin position="48"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="7"/>
            <end position="19"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006283"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF13867"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OBZ86140.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="111" mass="12779" checksum="C29940AFBF4E40FA" modified="2016-11-30" version="1">MGVKQKPIQSTFSNGVSQNPDRERDKKRRTAETNVGKEFQTIDFNSMDTSVLRKYARVHKLKVKSKANKEELAATVSRHFAXQTVKELDTITCFLYTAHYKDSVLRLPLHI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NAZ6</accession>
    <name>A0A1C7NAZ6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">SAP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_05751</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000320">
        <property type="protein sequence ID" value="OBZ86201.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NAZ6"/>
    <dbReference type="STRING" id="101091.A0A1C7NAZ6"/>
    <dbReference type="InParanoid" id="A0A1C7NAZ6"/>
    <dbReference type="OrthoDB" id="445357at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.720.30">
        <property type="entry name" value="SAP domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003034">
        <property type="entry name" value="SAP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036361">
        <property type="entry name" value="SAP_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02037">
        <property type="entry name" value="SAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00513">
        <property type="entry name" value="SAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF68906">
        <property type="entry name" value="SAP domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50800">
        <property type="entry name" value="SAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SAP" evidence="2">
        <location>
            <begin position="192"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="116"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="290"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="346"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="294"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="346"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="370"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="384"/>
            <end position="393"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50800"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ86201.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="489" mass="55567" checksum="BC4DD512A0C90945" modified="2016-11-30" version="1">MDFNHDKDNPFDLYSYPLESHSLPVDSFLMNDLFQEQDFHHQAILLTDPNFTRQQQLLQKAKEQPRSNLSAMLDNTKTTEPIPIHNTILSSSVPNTVDHQRRFNELQARFRVNYNRKPTSPVEKPITNPPNTKPVRLNRTKPAESPPPLSSSLPSRTMPIQIQRMQRNTPSQPFDLEQRQKRLDDQLVKVDFDDITVAELKEMLRQRGKPATGKKAVLLQRLQEEREMIQHARANGIPILHRHAMNHQSPVIPSPMMDSHYAASVPESVFSSSPLSSSLNGLHCSIANMHIGSPPSPQAPLPPSASSVAQSRRFAPYNTRPNSIMSSYSYSSSVPVHGNNLDAMMQQAQQAQQQAQQAQQAQQAHHHHNQQQQQQQQQQRELETSSWQPSITPEQEDFDDFGSSSIKAQAIPIHSNTNDTIMDWTHPSVDFLLQPDYNHDFEGKSAEEILSMMHSIDNQYHDNIEDIMGHGPDLTSVMFDHTKGYPFSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NBJ5</accession>
    <name>A0A1C7NBJ5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Protein LAS1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">LAS1</name>
        <name evidence="1" type="ORF">A0J61_05447</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000294">
        <property type="protein sequence ID" value="OBZ86495.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NBJ5"/>
    <dbReference type="FunCoup" id="A0A1C7NBJ5">
        <property type="interactions" value="7"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NBJ5"/>
    <dbReference type="InParanoid" id="A0A1C7NBJ5"/>
    <dbReference type="OrthoDB" id="10263222at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090730">
        <property type="term" value="C:Las1 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030687">
        <property type="term" value="C:preribosome, large subunit precursor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000460">
        <property type="term" value="P:maturation of 5.8S rRNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000470">
        <property type="term" value="P:maturation of LSU-rRNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007174">
        <property type="entry name" value="Las1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15002">
        <property type="entry name" value="RIBOSOMAL BIOGENESIS PROTEIN LAS1L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15002:SF0">
        <property type="entry name" value="RIBOSOMAL BIOGENESIS PROTEIN LAS1L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04031">
        <property type="entry name" value="Las1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="316"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ86495.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="316" mass="36459" checksum="A2D61514B312EC68" modified="2016-11-30" version="1" fragment="single">MYQTRIVPWVNYQEFETVYQWLFADRKTQVDQVRRGIDRVQTWTNRGEIPSSVETTAALIEIIIHDEQSSHLSHKELRLTYAMALVRFVNGLVDREQKGKFAKSIQVLARSIGLPSWFVDLRHASTHEHLPSLMVLRDGAMQAVAWLHDHYWVRNLKKADQQNHDEIKSKLNQYKECRKSFMKEKYSAKSSDPDAYVACIQQLIEMIGYQEEQLQQDVIPLLLNVGGLVPTGKKKRASAEEMQISKGLIELWTPLIQGLDVGFPDFGRQLVKAMIKRLNINEEFKVNETLLNPYAAFATKEKTDDPTQAPSYLLTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-06-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NBQ3</accession>
    <name>A0A1C7NBQ3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_05425</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000292">
        <property type="protein sequence ID" value="OBZ86523.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="InParanoid" id="A0A1C7NBQ3"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008889588" evidence="2">
        <location>
            <begin position="22"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="84"/>
            <end position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ86523.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="109" mass="11258" checksum="D9535D68AE032EBE" modified="2016-11-30" version="1">MRQFXLITLALVVCLVDTAFGEVQSMASNEKQINKVVAGGSGVLIENDTFVAQAQANSKRGLLDNGGSGSGDLTGSLTKGIPINGLLGGGGEQVAQTESARGQSRKRRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NBV5</accession>
    <name>A0A1C7NBV5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_07116</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000464">
        <property type="protein sequence ID" value="OBZ84834.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NBV5"/>
    <dbReference type="InParanoid" id="A0A1C7NBV5"/>
    <dbReference type="OrthoDB" id="2286195at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004190">
        <property type="term" value="F:aspartic-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001969">
        <property type="entry name" value="Aspartic_peptidase_AS"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00141">
        <property type="entry name" value="ASP_PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="253"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="440"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ84834.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="440" mass="49746" checksum="A0C9A6632337844D" modified="2016-11-30" version="1" fragment="single">MAGDLRESHTEDVLNGSFDEEKSQKVEKAYHQLEVFRVASARQFPKVKEFVKEESNGGPRLQISELSCLMGVVERPEGKHGSVYRNIKGFTDHLERYCASQGIDLDFEHEKRMPSLLGKQYRAHYEAKRCAVSEQGTLVTWGMVKGWLDEYIDTPKQRALNIKALLSLAPREGEGGHEFAERWRDVLSSMNVEKFTIDEFIFVAVSNNFGYEWKQRXNAATNGSSGSIMKKSIDDMVTMFHNLDLVAERKRKHEGYQGGNANKSGRFNSPAGGTGASKWANHKLAKDKFCRRCGVAWQKGHREICPKWNGGDRGQPQVNRMATMAKPEEEASPVDEQLDDIADSLAESIDISDLEDDKMPCKHKKSREGELVHFIDGETDVPIYVEMHPIRALVDSGANFSSLNKAFCIQNKIPILKYQEDKQPVIHLATTEATIKRYGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NC39</accession>
    <name>A0A1C7NC39_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">RNA polymerase II subunit A C-terminal domain phosphatase</fullName>
            <ecNumber evidence="6">3.1.3.16</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">fcp1_0</name>
        <name evidence="10" type="ORF">A0J61_05285</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">This promotes the activity of RNA polymerase II.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>O-phospho-L-seryl-[protein] + H2O = L-seryl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:20629"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="EC" id="3.1.3.16"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:47004"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="EC" id="3.1.3.16"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.16" evidence="6"/>
    <dbReference type="EMBL" id="LUGH01000281">
        <property type="protein sequence ID" value="OBZ86673.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NC39"/>
    <dbReference type="FunCoup" id="A0A1C7NC39">
        <property type="interactions" value="355"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NC39"/>
    <dbReference type="InParanoid" id="A0A1C7NC39"/>
    <dbReference type="OrthoDB" id="10249888at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008420">
        <property type="term" value="F:RNA polymerase II CTD heptapeptide repeat phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd17729">
        <property type="entry name" value="BRCT_CTDP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd07521">
        <property type="entry name" value="HAD_FCP1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10190">
        <property type="entry name" value="BRCT domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.10">
        <property type="entry name" value="S15/NS1, RNA-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001357">
        <property type="entry name" value="BRCT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036420">
        <property type="entry name" value="BRCT_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039189">
        <property type="entry name" value="Fcp1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004274">
        <property type="entry name" value="FCP1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011947">
        <property type="entry name" value="FCP1_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02250">
        <property type="entry name" value="FCP1_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23081">
        <property type="entry name" value="RNA POLYMERASE II CTD PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23081:SF36">
        <property type="entry name" value="RNA POLYMERASE II SUBUNIT A C-TERMINAL DOMAIN PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00533">
        <property type="entry name" value="BRCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03031">
        <property type="entry name" value="NIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00292">
        <property type="entry name" value="BRCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00577">
        <property type="entry name" value="CPDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52113">
        <property type="entry name" value="BRCT domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50172">
        <property type="entry name" value="BRCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50969">
        <property type="entry name" value="FCP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FCP1 homology" evidence="9">
        <location>
            <begin position="56"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="domain" description="BRCT" evidence="8">
        <location>
            <begin position="292"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="386"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="427"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="399"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="440"/>
            <end position="502"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00047761"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00048336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU366066"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50969"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OBZ86673.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="513" mass="59255" checksum="FA9875A0990FDBA9" modified="2016-11-30" version="1">MSCLHEMIFEGLCAICGQTVDTGSKDHINMTHNTTGITVSLVEAERLEKQDRERLLKEKKLSLIVDLDQTVLHATWEPNIANWVDEQKAKNSVKDLRTFSLDGSMNKYTIKLRPGLDAFLKEMSKYYEMHVYTMGTRSYANAVAKEIDPDGSLFQDRILTRDENKDKSTTKKYLERLFPSDQSKVVILDDRADVWDYSPHLIQVKPYEFFYGIGDINAPTNSPVIIEDTVNKSPPKQDSIQLEQDHRPNYIPDPNDADDILTVIQKILINIHTQYYQHYEQTNNTATILSQLKSDILKDCHIVFSGVIPLQTKPQDSSIWRMATSFGARCFEDLTGKATHLIAASPGTNKFNTAIRYQHIKIVYPTWLTNSIWHWKKEDETKYLVPHNKREGSNTSEVENPEEAQLDFDDGLGFEWEDDEVDAILMESEDDKSSLKQEQTEEEEDEDEEDEDIEDWLGAELSGSEEGDDVAYGEEHEDEDQDKEEEEDEDDDKEEEKEDDEDLRSQKRIKRVY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NCI9</accession>
    <name>A0A1C7NCI9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Putative mitochondrial carrier C4G8.08</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">A0J61_06894</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000438">
        <property type="protein sequence ID" value="OBZ85064.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NCI9"/>
    <dbReference type="InParanoid" id="A0A1C7NCI9"/>
    <dbReference type="OrthoDB" id="250329at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031966">
        <property type="term" value="C:mitochondrial membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005381">
        <property type="term" value="F:iron ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002067">
        <property type="entry name" value="MCP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45758:SF3">
        <property type="entry name" value="MITOCHONDRIAL SUBSTRATE CARRIER FAMILY PROTEIN E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45758">
        <property type="entry name" value="MITOFERRIN-1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00926">
        <property type="entry name" value="MITOCARRIER"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 9 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 10" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="75"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="172"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="209"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="9">
        <location>
            <begin position="4"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="9">
        <location>
            <begin position="116"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="9">
        <location>
            <begin position="205"/>
            <end position="294"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="OBZ85064.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="303" mass="33870" checksum="17F4E04398B137DC" modified="2016-11-30" version="1">MSNTIDSYYVFASSAAGLVARTITHPIDTINIRLQTTTLQSTQPRSAHVFKTIIFPDLVDRNTSFKEKMQSVKGLYRGLPVALFFAVPALSVYLSCYESTKRKLSTTYHVPQDSSLNHLISGCAAEVAGGLLFTPMEVMKNRLQTQRGQHVGLRLFVSNIYKQEGFRGFFRGYWMGLAVFVPHSMAYFATYEKLKQWVLSKVDKKHFSIYMACSSTAGVASILISTPLDIIKTRWQISAAEQGKAYRDGPIAIAKNMLLKEGRGAFIRGIYARIAWGIPTTAISMTVFEVLKDNKSKILNILN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NCT9</accession>
    <name>A0A1C7NCT9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 9">Histone deacetylase</fullName>
            <ecNumber evidence="2 9">3.5.1.98</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="primary">phd1</name>
        <name evidence="15" type="ORF">A0J61_05123</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>N(6)-acetyl-L-lysyl-[histone] + H2O = L-lysyl-[histone] + acetate</text>
            <dbReference type="Rhea" id="RHEA:58196"/>
            <dbReference type="Rhea" id="RHEA-COMP:9845"/>
            <dbReference type="Rhea" id="RHEA-COMP:11338"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29969"/>
            <dbReference type="ChEBI" id="CHEBI:30089"/>
            <dbReference type="ChEBI" id="CHEBI:61930"/>
            <dbReference type="EC" id="3.5.1.98"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8 9">Belongs to the histone deacetylase family. HD Type 1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.5.1.98" evidence="2 9"/>
    <dbReference type="EMBL" id="LUGH01000268">
        <property type="protein sequence ID" value="OBZ86828.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="FunCoup" id="A0A1C7NCT9">
        <property type="interactions" value="83"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NCT9"/>
    <dbReference type="InParanoid" id="A0A1C7NCT9"/>
    <dbReference type="OrthoDB" id="1918432at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000792">
        <property type="term" value="C:heterochromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034399">
        <property type="term" value="C:nuclear periphery"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070210">
        <property type="term" value="C:Rpd3L-Expanded complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034967">
        <property type="term" value="C:Set3 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0141221">
        <property type="term" value="F:histone deacetylase activity, hydrolytic mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0040029">
        <property type="term" value="P:epigenetic regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045835">
        <property type="term" value="P:negative regulation of meiotic nuclear division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032874">
        <property type="term" value="P:positive regulation of stress-activated MAPK cascade"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045727">
        <property type="term" value="P:positive regulation of translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.800.20:FF:000007">
        <property type="entry name" value="Histone deacetylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.800.20">
        <property type="entry name" value="Histone deacetylase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003084">
        <property type="entry name" value="HDAC_I/II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000286">
        <property type="entry name" value="HDACs"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023801">
        <property type="entry name" value="His_deacetylse_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037138">
        <property type="entry name" value="His_deacetylse_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023696">
        <property type="entry name" value="Ureohydrolase_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10625:SF36">
        <property type="entry name" value="HISTONE DEACETYLASE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10625">
        <property type="entry name" value="HISTONE DEACETYLASE HDAC1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00850">
        <property type="entry name" value="Hist_deacetyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037913">
        <property type="entry name" value="His_deacetylse_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01270">
        <property type="entry name" value="HDASUPER"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01271">
        <property type="entry name" value="HISDACETLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52768">
        <property type="entry name" value="Arginase/deacetylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 9" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="3 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="12" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 9" id="KW-0804">Transcription</keyword>
    <keyword evidence="5 9" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Histone deacetylase" evidence="14">
        <location>
            <begin position="63"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="459"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="13">
        <location>
            <begin position="462"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="10">
        <location>
            <position position="176"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="134"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="184"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="211"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="213"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="300"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="339"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012111"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRNR" id="PIRNR037913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR037913-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR037913-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR037913-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF00850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="OBZ86828.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="486" mass="56018" checksum="C3C1E5A3AA756F12" modified="2016-11-30" version="1">MVRRSYNDDDDDESSTFSEDYXSQQKAKYMSASNSVRLASHNKTRVAYFHDEGVGNYHYGERHPMKPHRLTLTNHLVLKYGMHDKMEIFQPRRATDDEILNFHSSDYVDFLKRVTPDNADNYEKLFQRFNVGDDCPIFDGIYDFCQRYAGATIEASRKLIANGADICINWSGGLHHAKKSEASGFCYVNDIVLGILELLRYFPRVLYIDIDIHHGDGVQEAFYSTDRVMTVSFHKYNGDFFPATGHIDEIGASLGKYYSVNVPLRDGIDDEAYVWMFKEVIDSVIEAFRPSAIVLQCGADSLGCDRLGCFNLSINAHGHCVKIVKNYNIPLLVVGGGGYTVRNVARCWTYETSVLVDTTLDENLPPNEYIDFFKPDYKLHPDLKGRVENQNDQAYLMRVRERVLEQLRYLDHAPSIQMQEIPPDIQGFLDGEEEQRDAEEDTERNKDRRYVTGRRVAHEAEWFENDQDNEGEAQDSLWHNRMDLDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NCW7</accession>
    <name>A0A1C7NCW7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_06747</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000422">
        <property type="protein sequence ID" value="OBZ85204.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NCW7"/>
    <dbReference type="InParanoid" id="A0A1C7NCW7"/>
    <dbReference type="OrthoDB" id="8117402at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="2">
        <location>
            <begin position="92"/>
            <end position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ85204.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="152" mass="17137" checksum="A9B879C84B89B947" modified="2016-11-30" version="1">MLIKHCYSXEEEEVDHHHEDDIDDLIIPSSPLSSCSSLSSAPDSPLLQSTTSVSPTPLSPFSLYHHHKKTSSKKPTLSAKAEQFLNSIYPPLQCPSCNQLFGRKTNVIKHLTEAHIGQEPYRCIYPSCNHPRLYATREGLVYHIVHAHDKIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7ND63</accession>
    <name>A0A1C7ND63_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Septation initiation network scaffold protein cdc11</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">cdc11</name>
        <name evidence="4" type="ORF">A0J61_06640</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000411">
        <property type="protein sequence ID" value="OBZ85314.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7ND63"/>
    <dbReference type="STRING" id="101091.A0A1C7ND63"/>
    <dbReference type="InParanoid" id="A0A1C7ND63"/>
    <dbReference type="OrthoDB" id="7451790at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061499">
        <property type="term" value="C:outer plaque of mitotic spindle pole body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035591">
        <property type="term" value="F:signaling adaptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902412">
        <property type="term" value="P:regulation of mitotic cytokinesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031028">
        <property type="term" value="P:septation initiation signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052574">
        <property type="entry name" value="CDIRP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47566">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47566:SF1">
        <property type="entry name" value="PROTEIN NUD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00364">
        <property type="entry name" value="LRR_BAC"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SMART" id="SM00365">
        <property type="entry name" value="LRR_SD22"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="10"/>
            <end position="19"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OBZ85314.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="846" mass="97864" checksum="A70FAE5DA25E8DEB" modified="2016-11-30" version="1">MEEDWDLVDSSSSSQLSQQKNKEDSRPSLDFSRFNSTPNAYDLDNPISPLLIPHEDTEDLFCQSPIPDNESFYGQDIYQDASIEELGIKMHEADLTKKEQEDETMDEMQEQVCSEPDKETDRSITIEETNDTRANDDDTMDHNNESGNHCDIYPVDHEKAHFDFLFTHFVNPATPVNSTEDTRESEADRNTFWKNTTTGSSVPFMIPALATPNLDDQEQSETVIPPFNFSQANPTYLYTPNKEKAIKENFERLQEQVNVNPSSTSIENEKKEDSIMNNRTIKPLKKRTPQLSIKSLSPYAFSPTKPPFLTLHQPFSFDIPPLDNSDEDEQTEEADPSVIRRSLAECFAFAPTIDNEFLQSDPVDDNEHGLATLLYELERICPVASEWYRLTKLNLSRQNLISICDLNKHFPYLETLQISHNQLKTISGLPSLLIYLHASHNKLSEVDIYELDRLQHLDVSNNSITAFEDMSRLKSLRRLDASHNAITSCKAFQNLSGLLSLSLKANCLRRLINFEAVIENNQLESLDVSFNRIEYLSAVENLNQLRELNADHNDIQYVQLTKPMKRLCRLQLCFNRLKSFDMSLFPDLRVLYLDDNQIQRIIGMSSVTPLGSFSIRDQGREAIEFNIQCLRASQKLYLSGNPSPNLNHLVDFYSLQYLELCSAGLEQLPSDFSKYVPNLITLNLSMNRLENIWPLRKLRYLKRLLLIQNRLISLNEVIRVVQCMRQLHYLDLRQNPMSSNIYPPLNTTNILQKHSQEIVSPYVAMVQDDGWALKDLMFYENLSDHWRTRRQVYRALFMHKCPRLIELDQIKIEPTDRSEGDIVIDHFRRTQTPHTLSSNESFSYQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NDP2</accession>
    <name>A0A1C7NDP2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Restriction of telomere capping protein 4</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">A0J61_04718</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">May be involved in a process influencing telomere capping.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the RTC4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000237">
        <property type="protein sequence ID" value="OBZ87223.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NDP2"/>
    <dbReference type="STRING" id="101091.A0A1C7NDP2"/>
    <dbReference type="InParanoid" id="A0A1C7NDP2"/>
    <dbReference type="OrthoDB" id="128308at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039024">
        <property type="entry name" value="RTC4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028094">
        <property type="entry name" value="RTC4_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR41391">
        <property type="entry name" value="RESTRICTION OF TELOMERE CAPPING PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR41391:SF1">
        <property type="entry name" value="RESTRICTION OF TELOMERE CAPPING PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14474">
        <property type="entry name" value="RTC4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01312">
        <property type="entry name" value="RTC4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Restriction of telomere capping protein 4 C-terminal" evidence="9">
        <location>
            <begin position="242"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="377"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="18"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="384"/>
            <end position="404"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00009461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00015162"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM01312"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OBZ87223.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="413" mass="46947" checksum="BD30CE7A033B4D4A" modified="2016-11-30" version="1">MVSDEPQASSISAPSKVDMSRFKELTGKSKRSYEEDEGLDDFQPDKKPKPSSQPEKPKNTLTLPKRSHNVARGSPQASNDAMLNDPFRPEGGATFKDLRRNRLTLPKKVSRTPNPFPHANKKIIESSKDDNKEQCPYCGEVFKAMTGPLRRALDTIKKKDREYEKSQSAKLEEESATSIYNLPTDLTIKRRVLPAEKDAFCKLHRIELVIKPEGRKKNYPEEIAFDKIERRIDRMRPDLDKIIRNDLSSEFRDIAENAYKNMGANKARSTMGVMTRFEATLPGYYGPKGAAVILEALTKFYLETGFLSRELVSPQLPLEFAQQVLVPEVGLRLIQGDLTKHKVLPNARAKARKVMEESIQYGHHIFPVKDQEIESSSLTNVLESDAEEEEEEEEVEDDDGVQELELEHIEDSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NEC8</accession>
    <name>A0A1C7NEC8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">RING-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">A0J61_04488</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000221">
        <property type="protein sequence ID" value="OBZ87452.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NEC8"/>
    <dbReference type="STRING" id="101091.A0A1C7NEC8"/>
    <dbReference type="InParanoid" id="A0A1C7NEC8"/>
    <dbReference type="OrthoDB" id="10009520at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd20353">
        <property type="entry name" value="Rcat_RBR_RNF216"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1750">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051628">
        <property type="entry name" value="LUBAC_E3_Ligases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047546">
        <property type="entry name" value="Rcat_RBR_RNF216"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047544">
        <property type="entry name" value="RING-HC_RBR_RNF216"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044066">
        <property type="entry name" value="TRIAD_supradom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22770:SF42">
        <property type="entry name" value="FINGER PROTEIN (ZIN), PUTATIVE (AFU_ORTHOLOGUE AFUA_4G03910)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22770">
        <property type="entry name" value="UBIQUITIN CONJUGATING ENZYME 7 INTERACTING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26200">
        <property type="entry name" value="Rcat_RNF216"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26191">
        <property type="entry name" value="RING-HC_RBR_RNF216"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51873">
        <property type="entry name" value="TRIAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="6" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <keyword evidence="5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="8">
        <location>
            <begin position="244"/>
            <end position="502"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51873"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OBZ87452.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="570" mass="65791" checksum="F5AAD84A9CDAB74C" modified="2016-11-30" version="1">MSSKRKEDLDDKHLSQLLGLFPNGDPEYFRSCLGHYSQDPVERIADKVITELGGHYPQLPKFKRGDNRLNACLRILALDLFPDCDISFLRDRVLQYSYAHVEQVADYILSIRIYPERLEYGKMDIAESIRSDTYKTQAQLQLIHDFPQIWKSSIRAVLAENNWDYLKCYDQLKSFGSHGFWNTLKNFFLHWSSTPSHRDKLKVSDYSLLDQLDQLRQRGIKIQVENDKKLAHGINFDEYTECHQLITCDCCYGDQSFEQLIFCSEGQHAFCFDCITHFVTEGLFGQGSLRGQPRIHCISSTDSCLGCLPTRSLREVMTKDLWNTYEHSLLENSYKEEQQVQCCACPYFELDESIRPLESINGNGMLRTVARWIMWDIERDIQIAYSRVVIARRGNTFQCKNQDCKTLTCLTCHRPIRGAHICWEKESDGLRLFVEKAMADAVKRTCPNCSLSFQKLDGCNKITCPCGYKMCYICRKDIGKESYAHFCDHFRSIPGSKCTQCNRCDLYKTDSDDEAVSKAAERAKAQYLLAHPEVVHPDVSIGPAGSLERFVQMKQNAVLWLLERGVERLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NEP7</accession>
    <name>A0A1C7NEP7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Saccharopine dehydrogenase NADP binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">A0J61_04376</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the saccharopine dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000213">
        <property type="protein sequence ID" value="OBZ87575.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NEP7"/>
    <dbReference type="STRING" id="101091.A0A1C7NEP7"/>
    <dbReference type="InParanoid" id="A0A1C7NEP7"/>
    <dbReference type="OrthoDB" id="10268090at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009247">
        <property type="term" value="P:glycolipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051276">
        <property type="entry name" value="Saccharopine_DH-like_oxidrdct"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005097">
        <property type="entry name" value="Sacchrp_dh_NADP-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12286">
        <property type="entry name" value="SACCHAROPINE DEHYDROGENASE-LIKE OXIDOREDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12286:SF5">
        <property type="entry name" value="SACCHAROPINE DEHYDROGENASE-LIKE OXIDOREDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03435">
        <property type="entry name" value="Sacchrp_dh_NADP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="284"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="domain" description="Saccharopine dehydrogenase NADP binding" evidence="3">
        <location>
            <begin position="11"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00038048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF03435"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OBZ87575.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="419" mass="47701" checksum="52BBCBC2BC467A55" modified="2016-11-30" version="1">MTDYNTRKYDIVIFGATGFTGALTAEYLAEIKDKDLSWAISGRTLSKLEKTRERLVKIDPSLKDLDLLIADTSNPDSLDEVLSQTRVVITTVGPYTKYGTPLVEACLRQRTHYVDLTGEYGWTRRIIDDHHKEAQEKKVLIVPSCGFDSVPSDLGVYMVAQHMRNKHNLDLGYVKMSVTDADGGVSGGTVQSLLEVFTDPKLTRKEHMDPYLLSTRRGVDKFRWPTFKYDRDFSSKWQVMFIMAVVNERVVRRSWSIWSERGQGYGNMFSYEEYMSFLPVVASFIYHISLYTFVPFLTCMFKLFPSSTEKFKSIMPGSGFGPDEKKRSKGRFTMEFIATAETEPYDEPRRVRGIVKGFRDPGYGDTCRMICESALCIAKSLKDLPGKDGGVLTPSTAFGQVLIDRLTRNKEMIFKVEDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-06-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NEQ4</accession>
    <name>A0A1C7NEQ4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_04365</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000212">
        <property type="protein sequence ID" value="OBZ87585.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NEQ4"/>
    <dbReference type="InParanoid" id="A0A1C7NEQ4"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ87585.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="93" mass="10298" checksum="7E7B159CF6340F96" modified="2016-11-30" version="1">MLKFIFSIDPFAANVSALPLADSSMPCNLDEVGAAFPGSYANPACSTDNRLVQARKPDKPRFDFLHELKVHNHNSCQPDDPIPSRASSFWYTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NEV7</accession>
    <name>A0A1C7NEV7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">protein-serine/threonine phosphatase</fullName>
            <ecNumber evidence="2">3.1.3.16</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">A0J61_04315</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>O-phospho-L-seryl-[protein] + H2O = L-seryl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:20629"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="EC" id="3.1.3.16"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:47004"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="EC" id="3.1.3.16"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.16" evidence="2"/>
    <dbReference type="EMBL" id="LUGH01000209">
        <property type="protein sequence ID" value="OBZ87631.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NEV7"/>
    <dbReference type="STRING" id="101091.A0A1C7NEV7"/>
    <dbReference type="InParanoid" id="A0A1C7NEV7"/>
    <dbReference type="OrthoDB" id="277011at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004722">
        <property type="term" value="F:protein serine/threonine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd07521">
        <property type="entry name" value="HAD_FCP1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1000:FF:000192">
        <property type="entry name" value="CTD small phosphatase-like protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011948">
        <property type="entry name" value="Dullard_phosphatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004274">
        <property type="entry name" value="FCP1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050365">
        <property type="entry name" value="TIM50"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02251">
        <property type="entry name" value="HIF-SF_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12210">
        <property type="entry name" value="DULLARD PROTEIN PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03031">
        <property type="entry name" value="NIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00577">
        <property type="entry name" value="CPDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50969">
        <property type="entry name" value="FCP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0904">Protein phosphatase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FCP1 homology" evidence="10">
        <location>
            <begin position="151"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="52"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="56"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013081"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047761"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00048336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50969"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="OBZ87631.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="323" mass="36715" checksum="B7D15782054A1499" modified="2016-11-30" version="1">MSQERGPVCVLPPSTKPSLFQRSSRKSSTNKTTKSKKNTFLSFLLCCTLKKKNKKSKEPDSIRIDNILPHEKTTEPPVESDLVDQTLKQPSSSSIDEKGILTEDEETKSDVVVTAVEPDVTHAQTEEEEEEKTLDDHDSNVAFLLNPIEKQHRGRKCLVLDLDETLIHSSFKTVAEADFIVPVEIDGHYHNVFVLKRPGVDDFMRKMGELYEIVIFTASLSKYADPVLDKFDLHNVIHHRLFRESCHPYKGSYIKDLSRLGRDLKHVIILDNTPASYSFHPSNAVPVSTWFNDQHDSELIDLIPFLQDLSKVDDVVEVLNTSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NF32</accession>
    <name>A0A1C7NF32_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Protein SPT2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">A0J61_04228</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SPT2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000202">
        <property type="protein sequence ID" value="OBZ87723.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NF32"/>
    <dbReference type="FunCoup" id="A0A1C7NF32">
        <property type="interactions" value="42"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NF32"/>
    <dbReference type="InParanoid" id="A0A1C7NF32"/>
    <dbReference type="OrthoDB" id="6259853at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042393">
        <property type="term" value="F:histone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006334">
        <property type="term" value="P:nucleosome assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006360">
        <property type="term" value="P:transcription by RNA polymerase I"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013256">
        <property type="entry name" value="Chromatin_SPT2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22691:SF8">
        <property type="entry name" value="PROTEIN SPT2 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22691">
        <property type="entry name" value="YEAST SPT2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08243">
        <property type="entry name" value="SPT2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00784">
        <property type="entry name" value="SPT2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="13"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="57"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="22"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="72"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="88"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="112"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="152"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="213"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="252"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="314"/>
            <end position="339"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OBZ87723.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="416" mass="48578" checksum="9326DD642FB6B21A" modified="2016-11-30" version="1">MLNFDQLMAQATKVAKQQDASLMERARQKRREDEERQRRELKLLKEREAEQALLAKKRELQEKKQKALSAQKKMEKGRRVQNEKLASKSRTTVGSTNAFGSRKAMPVSSLLPEKKKPEHLSFEDLMKKAKEQTISKKTSDSKPSPTQATLTKKTEIRQSTNHHDHLNTSSLYHRSKRPDMTRPVATGTASHSLSARERARQMIAEPPKKLSVQKRDQRSISDVQREIRHSKGIYSDDESDRVRKVNRQRNSSPPPLPMPRKRVPSPPRRPMAGKRPPMDSKRPPAPQPRRMPFSGRPLDPHARRAVPKRRPRDEEDEDLDQDLAEFIVDDEDDDDEGDGYADFRRPRKNSYSDEISKIFRYDRNRYANEPVWSDDDMEANASDVLREEKRSERIARREDLIEEQKELERLKKKKRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NFL0</accession>
    <name>A0A1C7NFL0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Ubiquinone biosynthesis protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">Coq9</name>
        <name evidence="10" type="ORF">A0J61_04049</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Membrane-associated protein that warps the membrane surface to access and bind aromatic isoprenes with high specificity, including ubiquinone (CoQ) isoprene intermediates and presents them directly to Coq7, therefore facilitating the Coq7-mediated hydroxylase step. Participates in the biosynthesis of coenzyme Q, also named ubiquinone, an essential lipid-soluble electron transporter for aerobic cellular respiration.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 8">Cofactor biosynthesis; ubiquinone biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 8">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the COQ9 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000190">
        <property type="protein sequence ID" value="OBZ87892.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="FunCoup" id="A0A1C7NFL0">
        <property type="interactions" value="180"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NFL0"/>
    <dbReference type="InParanoid" id="A0A1C7NFL0"/>
    <dbReference type="OrthoDB" id="619536at2759"/>
    <dbReference type="UniPathway" id="UPA00232"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008289">
        <property type="term" value="F:lipid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006744">
        <property type="term" value="P:ubiquinone biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.357.10:FF:000004">
        <property type="entry name" value="Ubiquinone biosynthesis protein COQ9, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.357.10">
        <property type="entry name" value="Tetracycline Repressor, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013718">
        <property type="entry name" value="COQ9_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012762">
        <property type="entry name" value="Ubiq_biosynth_COQ9"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02396">
        <property type="entry name" value="diverge_rpsU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21427">
        <property type="entry name" value="UBIQUINONE BIOSYNTHESIS PROTEIN COQ9, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21427:SF19">
        <property type="entry name" value="UBIQUINONE BIOSYNTHESIS PROTEIN COQ9, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08511">
        <property type="entry name" value="COQ9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0446">Lipid-binding</keyword>
    <keyword evidence="7 8" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="10" id="KW-0830">Ubiquinone</keyword>
    <keyword evidence="4 8" id="KW-0831">Ubiquinone biosynthesis</keyword>
    <feature type="domain" description="COQ9 C-terminal" evidence="9">
        <location>
            <begin position="161"/>
            <end position="230"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004749"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010766"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022688"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU366063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF08511"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OBZ87892.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="260" mass="29256" checksum="77618D037C65D0D3" modified="2016-11-30" version="1">MSAIRSVFNHTIRQKNTFVGLCRPAFVRVYTMEHAASKQATVPPTQPKDPRVELLEATLPFVQKHGWSMESMMQGARSLGYPSVAHGIFSGGEAGLIDVHLAVQRENFVKQIKEKAEQGELEGLTMNEKIKLLTSMRLELNKPYIKQWPEALAIMARPSNVPMSLKHLGDIVDDIWYYAGDRSPDFNWYTKRASLAAVYSATDIFMTQDLSPNYIETXRFLSRKLDQANWIGSSARQLGTMLEFGARSMLSAVANRGGRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NFT4</accession>
    <name>A0A1C7NFT4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Transcriptional regulator of yeast-form-adherence 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">TRY3_1</name>
        <name evidence="7" type="ORF">A0J61_05726</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000318">
        <property type="protein sequence ID" value="OBZ86224.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NFT4"/>
    <dbReference type="STRING" id="101091.A0A1C7NFT4"/>
    <dbReference type="InParanoid" id="A0A1C7NFT4"/>
    <dbReference type="OrthoDB" id="5588846at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd23137">
        <property type="entry name" value="RING-HC_TRY3-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004331">
        <property type="entry name" value="SPX_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018957">
        <property type="entry name" value="Znf_C3HC4_RING-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017907">
        <property type="entry name" value="Znf_RING_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23327">
        <property type="entry name" value="RING FINGER PROTEIN 127"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23327:SF51">
        <property type="entry name" value="TRANSCRIPTIONAL REGULATOR OF YEAST FORM ADHERENCE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03105">
        <property type="entry name" value="SPX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00097">
        <property type="entry name" value="zf-C3HC4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51382">
        <property type="entry name" value="SPX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00518">
        <property type="entry name" value="ZF_RING_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="SPX" evidence="6">
        <location>
            <begin position="1"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="domain" description="RING-type" evidence="5">
        <location>
            <begin position="406"/>
            <end position="445"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OBZ86224.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="517" mass="60055" checksum="1F5CC8DF2506035C" modified="2016-11-30" version="1">MKFGKQLETEAEDIPSEWRPYLIQYKALKKIITRVAEEIESRGLSASLLHECLEDSGNEESFAIHDNEQDHDNDSIPKIKYYFIGEVPNVKPCIEFSYDPSEPKVQQMLSKLLISSETPNQDADRPKLEYKRSHNNKDIFSLSSSINSGEEDVLHSPAFTRQRRDSTVQLVKELVKLTLAERDRIKDSHEHEDMTERTESMERGKLKTLVIELEQDDEFFKLLLAELDQAAKLQNVTSQRFEEDINSLELCMIKAAAPTQKSEMYHWRKIFSVYMDAQIFQGNAEADRTFRSVERAKRQMTWFVEQLNKQDLLKKFKTKESKSAFEQFIALNTELITMKHYQVLNQTAMRKILKKHDKRSGLTASQSFPELVSTEQLFSPKLAGMLYATITSKLTSIIPQPDDYACPVCMNVAWRPIRLRCDHVFCVRCLVKAQKKKMNGCPLCRHPTAVRDATALNLDEGLQNFLKLYFPQEIKEKKRDNEREQAIEDIQAMTGKKYSEEQLMRMSQQSHNKCLIM</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NGH1</accession>
    <name>A0A1C7NGH1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Elongator complex protein 6</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">elp6</name>
        <name evidence="3" type="ORF">A0J61_03874</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">tRNA modification; 5-methoxycarbonylmethyl-2-thiouridine-tRNA biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ELP6 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000176">
        <property type="protein sequence ID" value="OBZ88080.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NGH1"/>
    <dbReference type="STRING" id="101091.A0A1C7NGH1"/>
    <dbReference type="InParanoid" id="A0A1C7NGH1"/>
    <dbReference type="OrthoDB" id="9995306at2759"/>
    <dbReference type="UniPathway" id="UPA00988"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033588">
        <property type="term" value="C:elongator holoenzyme complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002098">
        <property type="term" value="P:tRNA wobble uridine modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd19495">
        <property type="entry name" value="Elp6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018627">
        <property type="entry name" value="ELP6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16184">
        <property type="entry name" value="ELONGATOR COMPLEX PROTEIN 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16184:SF6">
        <property type="entry name" value="ELONGATOR COMPLEX PROTEIN 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09807">
        <property type="entry name" value="ELP6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ88080.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="269" mass="30097" checksum="46E17559B1D7083E" modified="2016-11-30" version="1">MGYATLDAALAFPNNVVPKSAHIVITDTLKSDANFLIHHFIVNHLKNDKPVILVGFSQIFNHYFLIARKLASSLLFLFGVNLQTYKQSDKFVFIDGLTHLNGYTMQTPYPPSNAPTAPTDTLNFNGSHSMKSFYQTIAAYNKPDTLIILDDISCFLYNKFDHVNTFLPKLKTLVERTQGTLLTVMHADEGGVEDTEQDNFVKQTIYGSSLVLQVQPLHSGLARDVHGQLDVIYGPQCTPLIEKHTPAQSMHYKILDNNVHFFAKGIAQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NGM7</accession>
    <name>A0A1C7NGM7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Enoyl-CoA delta isomerase 2, mitochondrial</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">Eci2</name>
        <name evidence="4" type="ORF">A0J61_03644</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Peroxisome</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000161">
        <property type="protein sequence ID" value="OBZ88301.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NGM7"/>
    <dbReference type="STRING" id="101091.A0A1C7NGM7"/>
    <dbReference type="InParanoid" id="A0A1C7NGM7"/>
    <dbReference type="OrthoDB" id="448450at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005777">
        <property type="term" value="C:peroxisome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004165">
        <property type="term" value="F:delta(3)-delta(2)-enoyl-CoA isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd06558">
        <property type="entry name" value="crotonase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.226.10">
        <property type="entry name" value="2-enoyl-CoA Hydratase, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.12.10">
        <property type="entry name" value="Lyase 2-enoyl-coa Hydratase, Chain A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051053">
        <property type="entry name" value="ECH/Chromodomain_protein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001753">
        <property type="entry name" value="Enoyl-CoA_hydra/iso"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014748">
        <property type="entry name" value="Enoyl-CoA_hydra_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43684">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43684:SF1">
        <property type="entry name" value="ENOYL-COA DELTA ISOMERASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00378">
        <property type="entry name" value="ECH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="ClpP/crotonase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4" id="KW-0413">Isomerase</keyword>
    <keyword evidence="2" id="KW-0576">Peroxisome</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004275"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OBZ88301.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="278" mass="30929" checksum="C8B77591F22A9384" modified="2016-11-30" version="1">MVISIPLLESFQITLNSSGVTEIAFNRPKKFNALSPQVYRDWLAVLRWAAQSDAVKVVVMTGRGPYYTSGQELQEPDYSPAGQEFNRNRRLVTKALVDTFIQFPKLLIAGVNGNAIGFGVTSLALCDVVYSVPDATFSTPFMKLGYCAEGCSSVLFPRIMGSSKANEMLLMGRTFTAQELVDCGMVSRILPAEEFHGRVLALAEEAAKFSGEAIAISKRLIRDVDRQLLLNTNEIEMIRLDERSRSKDSQDAIMRFMEDQKRKKAAKLARQAQSQSKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NGR0</accession>
    <name>A0A1C7NGR0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">PHD-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">A0J61_03793</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000171">
        <property type="protein sequence ID" value="OBZ88160.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NGR0"/>
    <dbReference type="STRING" id="101091.A0A1C7NGR0"/>
    <dbReference type="InParanoid" id="A0A1C7NGR0"/>
    <dbReference type="OrthoDB" id="5863171at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019786">
        <property type="entry name" value="Zinc_finger_PHD-type_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001965">
        <property type="entry name" value="Znf_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019787">
        <property type="entry name" value="Znf_PHD-finger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00628">
        <property type="entry name" value="PHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00249">
        <property type="entry name" value="PHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01359">
        <property type="entry name" value="ZF_PHD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50016">
        <property type="entry name" value="ZF_PHD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="PHD-type" evidence="5">
        <location>
            <begin position="58"/>
            <end position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OBZ88160.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="136" mass="15852" checksum="7E3CF6815EB288DF" modified="2016-11-30" version="1">MADIRGLTTTNQTTQPTDFSKAYRPVYVFYVNLALLQAEQSQGITLEDYTLEEEEEESIPCMHCGIKEIADDINDIFFCESCHQGVHQLCEDPPIQSFELKIDPWYCRTCCRNKNLPIPILEDTFLSHKRKREEEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NH81</accession>
    <name>A0A1C7NH81_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_03489</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000151">
        <property type="protein sequence ID" value="OBZ88457.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NH81"/>
    <dbReference type="STRING" id="101091.A0A1C7NH81"/>
    <dbReference type="InParanoid" id="A0A1C7NH81"/>
    <dbReference type="OrthoDB" id="2100128at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39398:SF1">
        <property type="entry name" value="CSN8_PSMD8_EIF3K DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39398">
        <property type="entry name" value="YALI0F14311P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="26"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="34"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="69"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ88457.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="337" mass="39126" checksum="33A5774E94FD9A83" modified="2016-11-30" version="1">MSNKKAPIEGLTIRIWDLDNEVEKSDVNNRGSRGYREYTEQIGSDKLKHNVHKFNNDKNEEENQGLKKSTRDWTAEKEKANSVEELSLVSRSDNTNPKQSLKSVELQHELWSLILSKVSQIEDDFDPKAWSPIVDLLRKLREGVYASEWSRGDYDFAIKVFELSVDCCIKAGRFEELSKSLLGLMDQLYAIKKEAVQPYYTVLDIIYQCCHTQNPKAANRRITLVSLDTNEGVFGRSLIKSVVNNNPIRYFEHYHYNPYPTFKLLMTKYNDSMRILAIEMLCKAYLSAPIAWVGKWIGIYHDNGEVLKEMERLIQPTCIKSIDYDAQVVYFLKKSKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NHG1</accession>
    <name>A0A1C7NHG1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Inositol polyphosphate 5-phosphatase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">INPP5E</name>
        <name evidence="3" type="ORF">A0J61_03385</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000144">
        <property type="protein sequence ID" value="OBZ88561.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NHG1"/>
    <dbReference type="STRING" id="101091.A0A1C7NHG1"/>
    <dbReference type="InParanoid" id="A0A1C7NHG1"/>
    <dbReference type="OrthoDB" id="405996at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004439">
        <property type="term" value="F:phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046856">
        <property type="term" value="P:phosphatidylinositol dephosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.10.10">
        <property type="entry name" value="Endonuclease/exonuclease/phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036691">
        <property type="entry name" value="Endo/exonu/phosph_ase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046985">
        <property type="entry name" value="IP5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000300">
        <property type="entry name" value="IPPc"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11200">
        <property type="entry name" value="INOSITOL 5-PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11200:SF275">
        <property type="entry name" value="LD06095P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22669">
        <property type="entry name" value="Exo_endo_phos2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00128">
        <property type="entry name" value="IPPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56219">
        <property type="entry name" value="DNase I-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Inositol polyphosphate-related phosphatase" evidence="2">
        <location>
            <begin position="22"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="340"/>
            <end position="377"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ88561.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="566" mass="65204" checksum="70CC8E327FAADE98" modified="2016-11-30" version="1">MIYMQQPNSRLDKALFFIKHPDRLKVFIGTWNMYGRLLPIDLSTFLTKTEVLENTATSVHLDDSVSHPYHLLVIGTQECERDISESLFYPSKEVWEKKLSEYLGVHYRLLKTETLAALHLAVFVWQPIAHLIKDVQSEHIKTGWANMVGNKGAVAVSVLVGSKSLIFINCHLRETKLSLLAHQTHVAERNANIQRILYELKMPKFKTQKKKKKNTDLCVLNQFDHVFLFGDTNYRLNAERSFVFQAIRNGDYKNLLEYDQLTEERRVEGSLLSAFQEHDILFPPTYKLDTIIVDSSSSLSDELKQGQKHLTEDACTLFNHTHPLSTYFSHHNVMINNKKKSPKLVRRSSTSSLPTAMATPSKLKAVDEKPVSRHKRGTSLTQIGRRLSKRYRSSASEPTIVLCSQEEAEDIHVHQESRIVLDGSPNITLCYDSSEKQRVPSWTDRILWYDQNASTMHKHSQKKDSIGKRLSTTTTILFPFKNRNKPIKDATLCYAYDAVLHESLMGVSDHMPVIGVFGIAFDEWNIVQQKLSRILPRKSTDTLPSMTKQSKPLKKKKKHWWRHLFH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NHG6</accession>
    <name>A0A1C7NHG6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_03488</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000151">
        <property type="protein sequence ID" value="OBZ88458.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NHG6"/>
    <dbReference type="InParanoid" id="A0A1C7NHG6"/>
    <dbReference type="OrthoDB" id="10339186at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ88458.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="417" mass="47848" checksum="05D973414B802743" modified="2016-11-30" version="1">MSWAELPSEILQQITKILGRDLSQFRLACNWWYQQAYGFPYHQFKVTGNVFEFTDIISKSPCHPGDIVRSITFTDDFAISDFNGRLKQIVDTIFRACPNIESIHCSPLARNLIWPCIIDNVNKNRCLQRVKYVGESSNMLTKYLKTDEESDLLYVHVMYALRESITLLKLFNDGYHNLLPAFAALRNRLCCFKSLTALRLHGCFAIEELNTILDSCQTIQVLIIFNDQLKPCIFGLMPSVPVTPHMRLRHLQIQNGLAQDRKDIEFILQKFPSLDSCVLERIDLVHQNDIALDATVQQLIRFGMQIKDFNVRFCHDSYPLSKLRTCLYHLESSMSVFVDICFTLDREMSHVHINKCNTKVSIYIAWDNSSASLDDLSSLSDLCNHASVQTKIHGKTTDAAKLAFLNSMTQNTIELCQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NHX9</accession>
    <name>A0A1C7NHX9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">PPP2R5D_2</name>
        <name evidence="10" type="ORF">A0J61_03190</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">PP2A consists of a common heterodimeric core enzyme, composed of a 36 kDa catalytic subunit (subunit C) and a 65 kDa constant regulatory subunit (PR65 or subunit A), that associates with a variety of regulatory subunits. Proteins that associate with the core dimer include three families of regulatory subunits B (the R2/B/PR55/B55, R3/B''/PR72/PR130/PR59 and R5/B'/B56 families), the 48 kDa variable regulatory subunit, viral proteins, and cell signaling molecules.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the phosphatase 2A regulatory subunit B family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000133">
        <property type="protein sequence ID" value="OBZ88752.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NHX9"/>
    <dbReference type="FunCoup" id="A0A1C7NHX9">
        <property type="interactions" value="423"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NHX9"/>
    <dbReference type="InParanoid" id="A0A1C7NHX9"/>
    <dbReference type="OrthoDB" id="10264446at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000775">
        <property type="term" value="C:chromosome, centromeric region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000159">
        <property type="term" value="C:protein phosphatase type 2A complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005816">
        <property type="term" value="C:spindle pole body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019888">
        <property type="term" value="F:protein phosphatase regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035556">
        <property type="term" value="P:intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051754">
        <property type="term" value="P:meiotic sister chromatid cohesion, centromeric"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901991">
        <property type="term" value="P:negative regulation of mitotic cell cycle phase transition"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098813">
        <property type="term" value="P:nuclear chromosome segregation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.10.10:FF:000016">
        <property type="entry name" value="Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002554">
        <property type="entry name" value="PP2A_B56"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10257">
        <property type="entry name" value="SERINE/THREONINE PROTEIN PHOSPHATASE 2A PP2A REGULATORY SUBUNIT B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10257:SF3">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN PHOSPHATASE 2A 56 KDA REGULATORY SUBUNIT GAMMA ISOFORM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01603">
        <property type="entry name" value="B56"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF028043">
        <property type="entry name" value="PP2A_B56"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008259"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00064351"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRNR" id="PIRNR028043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OBZ88752.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="657" mass="76380" checksum="94713FD70B0E98FB" modified="2016-11-30" version="1">MIKGWKEALTRTKTEKPMPVEPNTDMNNSPVNRDMPPDSPKPNGIISSSNVEMQQKGIRANTTTTTTINSNNAVSFMHSNSHAKDVPKTGPLHHRLKNAPIDQIPISKAPRRQKSSRFYVTEKVQLEPTPAFHEVPSHMRPDLFLKKIKQCTVIFDFSDASAELREKEIKRQTLQEILDHISMNRGVLTENVYPEIINMFAINLFRPIPPQVNPVGDAFDPEEDEPVLELAWPHLQTVYEFFLRFLESPEFNINFAKKHIDHKFILQLLDLFDSEDPRERDYLKTTLHRIYGKFLNLRAFIRRSINNIFFQFIYETERHNGIAEFLEILGSIINGFALPLKEEHKTFLSRVLIPLHKAKSLALYHPQLAYCVVQFLEKDRALTFEVVTGLLRYWPKVNSSKEVMFLNEMEEILDIIDIPEFQQIMCPLFTKLSQCVASPHFQVSERALYYWSNDYIVSLMAENIKIIMPIIFPTFYKTSKTHWNKNILSLVYTALKLCVDIDPALFDECANEYKNQRQLERKLQKEREDNWRHLQQKAEKIVASKKNGDHPSAHEIFEEYNTNSHYVFGQSDINDMLNELEELDMDDSQEIMSEHGGEQKDDIHPDMQQFETPPAQFQVFRRKSIIPVDETVYNELSRHVSLDEVLNQAPGAHSPSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NJR0</accession>
    <name>A0A1C7NJR0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">AMP deaminase</fullName>
            <ecNumber evidence="4">3.5.4.6</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Myoadenylate deaminase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="primary">ada1_0</name>
        <name evidence="13" type="ORF">A0J61_02635</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Purine metabolism; IMP biosynthesis via salvage pathway; IMP from AMP: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 11">Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.5.4.6" evidence="4"/>
    <dbReference type="EMBL" id="LUGH01000102">
        <property type="protein sequence ID" value="OBZ89305.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NJR0"/>
    <dbReference type="FunCoup" id="A0A1C7NJR0">
        <property type="interactions" value="379"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NJR0"/>
    <dbReference type="InParanoid" id="A0A1C7NJR0"/>
    <dbReference type="OrthoDB" id="1723809at2759"/>
    <dbReference type="UniPathway" id="UPA00591">
        <property type="reaction ID" value="UER00663"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003876">
        <property type="term" value="F:AMP deaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046033">
        <property type="term" value="P:AMP metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032264">
        <property type="term" value="P:IMP salvage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd01319">
        <property type="entry name" value="AMPD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="4.10.800.20:FF:000001">
        <property type="entry name" value="AMP deaminase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.140:FF:000035">
        <property type="entry name" value="Probable amp deaminase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.800.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.140">
        <property type="entry name" value="Metal-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006650">
        <property type="entry name" value="A/AMP_deam_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006329">
        <property type="entry name" value="AMPD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01429">
        <property type="entry name" value="AMP_deaminase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11359">
        <property type="entry name" value="AMP DEAMINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11359:SF0">
        <property type="entry name" value="AMP DEAMINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19326">
        <property type="entry name" value="AMP_deaminase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001251">
        <property type="entry name" value="AMP_deaminase_met"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="Metallo-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00485">
        <property type="entry name" value="A_DEAMINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0546">Nucleotide metabolism</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="131"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="12">
        <location>
            <begin position="141"/>
            <end position="152"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004955"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00072037"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00078830"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRNR" id="PIRNR001251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="OBZ89305.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="788" mass="90971" checksum="714F117E9F9BC05C" modified="2016-11-30" version="1">MPFSKKPTDGIDIPTDEGINNFDDSPYFDYHHLKAIENHDSKYLGQSLSVSPAGHHLSELHLNDQEFSDLTQVPENDVPQESTSINPKVKLEVKDDAVTAELRELYGALQKCLDLREKYIELSSQRLMDDPRNHDDWEIYPAPPPKSWPLPSPEELERRKAKEKAREADPVAAVGSDFDFDQCKIPDPHVYQYGICSDGYYQVYKNELDQVVNQPLHQFPSPREFFDDMEFVLSVISDGPAKSFAFRRLRYLDSKWQMYILLNEFQELADSKCTPHRDFYNVRKVDTHVHHSSSMNQKHLLRFIKSKMKKSPDDVVIYRDGHHLTLKGVFESLGLTAYDLSIDTLDMHAHKDSFHRFDKFNLKYNPIGESRLREIFMKTDNYIQGRYLAEITKEVVSDLESSKYQMVEYRVSIYGRSIDEWDKLAKWVVNNKLFSSNVRWLIQVPRLYNIYKASNAINNFQEYITNIFQPLFDVTQDPSRHPELHVFLQRVIGFDTVDDESKPEKPIYHDFPLPKDWTSNTNPPYSYYLYYLYANIASLNKWRQARKFNTLVLRPHCGEAGDTDHLTAAFLTSYGISHGILLRKVPALQYLYYLAQIGIAMSPLSNNALFLTYERNPLPQFFQRGLNISLSTDDPLQFHFTKEPLIEEYSVAAQIWKFSATDMCELARNSVIQSGWENQIKSHWIGQDWYKPGVEGNDMQKTNVPNIRVGFRYETLSEELDALRRYAPGAKKTDVSVNKQDLVGVAGLAENSSIQQHLLNGVSSSDSQMASFPGAGLVAERAKFRAGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NKU8</accession>
    <name>A0A1C7NKU8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="1">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">SAT4_0</name>
        <name evidence="10" type="ORF">A0J61_02502</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="1"/>
    <dbReference type="EMBL" id="LUGH01000095">
        <property type="protein sequence ID" value="OBZ89439.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="FunCoup" id="A0A1C7NKU8">
        <property type="interactions" value="541"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NKU8"/>
    <dbReference type="InParanoid" id="A0A1C7NKU8"/>
    <dbReference type="OrthoDB" id="6513151at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24343:SF558">
        <property type="entry name" value="PROTEIN KINASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24343">
        <property type="entry name" value="SERINE/THREONINE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 10" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="9">
        <location>
            <begin position="1"/>
            <end position="230"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OBZ89439.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="233" mass="27019" checksum="48F000B3DAA606BF" modified="2016-11-30" version="1">MKKLISEFCIASVLGHLNICKTLDLVLDEKKRYCIVMEYCSGGDLYSYIKEGHLXDSIDETHDLFKQLLTGLSYLHELGVAHRDIKPENLLLVKKREHCSILKITDFGEADVFRETWQPTNHRLSHGLCGSTPYIAPEIFLNFKQGYLASQSDVWSAGIVYFCMRMNGVPFFSAQRTDSNYRLYQKHYSLANYPAFDSFDHESRQMLYAMLNVNPDERLTVKDLLESNWLTRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NLT0</accession>
    <name>A0A1C7NLT0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">HTH APSES-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_01973</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000069">
        <property type="protein sequence ID" value="OBZ89988.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NLT0"/>
    <dbReference type="InParanoid" id="A0A1C7NLT0"/>
    <dbReference type="OrthoDB" id="5597783at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.260.10">
        <property type="entry name" value="Transcription regulator HTH, APSES-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036887">
        <property type="entry name" value="HTH_APSES_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003163">
        <property type="entry name" value="Tscrpt_reg_HTH_APSES-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057511">
        <property type="entry name" value="WH_GDS1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25318">
        <property type="entry name" value="WHD_GDS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54616">
        <property type="entry name" value="DNA-binding domain of Mlu1-box binding protein MBP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51299">
        <property type="entry name" value="HTH_APSES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH APSES-type" evidence="2">
        <location>
            <begin position="841"/>
            <end position="951"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="103"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="445"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="489"/>
            <end position="551"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="565"/>
            <end position="622"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="795"/>
            <end position="824"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1031"/>
            <end position="1100"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1115"/>
            <end position="1135"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1154"/>
            <end position="1303"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="12"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="165"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="187"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="220"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="238"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="250"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="300"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="322"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="447"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="489"/>
            <end position="527"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="531"/>
            <end position="551"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="565"/>
            <end position="574"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="575"/>
            <end position="622"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="811"/>
            <end position="824"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1036"/>
            <end position="1045"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1068"/>
            <end position="1079"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1118"/>
            <end position="1135"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1172"/>
            <end position="1182"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1188"/>
            <end position="1202"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1209"/>
            <end position="1235"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1239"/>
            <end position="1262"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1280"/>
            <end position="1303"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51299"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ89988.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="1303" mass="140490" checksum="A490B33ED0E44353" modified="2016-11-30" version="1">MAQKSTSHDNTQQKAKQPQQQQELEQEQPPPQQQRQGGGLPVSIHPDDAKDKVFTAILKALLKMGNKPSSPKELANIIVKHKYATLGGATPFATVSSRISQHFKRAAEHNPPRAPLLAKHVDQNHSRKINYSLATESVSKTADDSSHTAATDDDEERPNPLRTNSKTRRTPFSKAKRSLRSAHKPDEDDNENDEEEEDDDSEEEEERKDAHQQKRLKPNTYLSQESNASLPNLVNSNNDDEEEESEGEQSDYHEEMLKDADEEIDLQLPTGRRLSRRHSKITAKPQNTIDIKKTSPPASPKSTNYPNTSPASSTQSPEANNTTTTTVIDSTSSPSPATVTVTSAPNISNNNITIPASSSSAATPTTILPKPSNKLTVPQDNIPHAPTRKPSFSFSSGFANDQEFWTPFSFEHDFDNVFVHDGSTAHHIPFNIATPESVSVSELDDYFTSTGSTPNRSQRKSFSSAMLGPNDKSLLQKVLLASAARGVADRIEEKSEQETGGRPESIKAIKKEKGERDEKETKQEDALATKTVEQPTESVMSTADKSKSVSVSKLMDVKNSEDFVKFEDDEKKESSPSTAAVSSTAPVPVSEPPSTQTNSITSTNATAAAAPPPASSAANASTTNTGTAAIASSAPSTSNTPPVKKVAEILPATSTTLTAAEILKSMNIQNLNLSALHQMTSNIPSLQHLSPTFDLAKTMAAYMQSLAKSASASNPSSSSSSHSADLKTILARFPALEAFIKKDSPAPASNNTATTTPSTASGLSVLPLAPSTSSVSLVTPSSSIHCVAAGTATPPLLSPTATEHAPHLHNSTSSTATPTPSITAGSTEPIVHTLTPFNPPMYITLVDHIAVCVVVLPKTEHSPEYRIMRRVDSGFINGTVLLTAGGIETESERSMILSFEMERIRMPKKKSPLFGTWIPLRRAQELAVTCSIQHKLGHFLEDSIESFFPSPLPIQINARKPTRDSRLTALALAALRSTSDTTKNNGFVIPPISRQASSSGSMAAATQLQELLLTHPHKALKSNGLINTAREPLLGRFDEPEKTDKLLMTTKPTTTANQQEDKDESDVDVVNSSDSSVASNDEESDTESSSGTIHSATGLDKKKQAKFLQRVKPPPINTNAAALSSASTATTPTTSTATSAAALDLQEILSRVTSKQPLHIHPRDLQKKRRRSVDGKSDKEDIPEPAAKTSKSLHTSSPPLSSTRKKPSNHTNTNTSSKATKPSQVKKQPIANHTSVVKHRSEASNKKKKEEEIDNVVVEHKSLPAIQNSTATQPPIVKQEDEDEDDEDEDIDIGGSDFDDDLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NM05</accession>
    <name>A0A1C7NM05_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_01781</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000061">
        <property type="protein sequence ID" value="OBZ90171.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NM05"/>
    <dbReference type="InParanoid" id="A0A1C7NM05"/>
    <dbReference type="OrthoDB" id="10452613at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="25"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="33"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="52"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ90171.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="150" mass="17290" checksum="CFB6CB03A386DDB6" modified="2016-11-30" version="1">MASNDFIHTLQHIFCCRNVNGIDAHDSAPPSQPNETNQSTLAETPYILTDPDTNEELEDEDWEQQDQPAIAQPVYPYQEDFIHTDTEPEQAVLKEFEHANRPDEMEWFKTKINPEVIYSWKFDTDNDKSNNWESNVPAPVSNAPLEIITV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NM41</accession>
    <name>A0A1C7NM41_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">G patch domain and ankyrin repeat-containing protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">GPANK1</name>
        <name evidence="2" type="ORF">A0J61_01729</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000058">
        <property type="protein sequence ID" value="OBZ90213.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NM41"/>
    <dbReference type="STRING" id="101091.A0A1C7NM41"/>
    <dbReference type="InParanoid" id="A0A1C7NM41"/>
    <dbReference type="OrthoDB" id="4822at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000467">
        <property type="entry name" value="G_patch_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039146">
        <property type="entry name" value="GPANK1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20923">
        <property type="entry name" value="BAT4 PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20923:SF1">
        <property type="entry name" value="G PATCH DOMAIN AND ANKYRIN REPEAT-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01585">
        <property type="entry name" value="G-patch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00443">
        <property type="entry name" value="G_patch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50174">
        <property type="entry name" value="G_PATCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="G-patch" evidence="1">
        <location>
            <begin position="108"/>
            <end position="155"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50174"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ90213.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="205" mass="23263" checksum="B71FBA0C99D82D2B" modified="2016-11-30" version="1">MSNNLNNAKKTTIVSKYARPIHFVAAKEQKEKPLKRQKKESDGQQVASLYHSIVSTNAKKNKEVKEEMTFCEDCQLNTKDYKRHLLGTAHMVSSKSTVAAPDLLKLDGRNVGFQMMVSQGWQHEVGGLGPQQSGRRHPIATVLKQDRLGIGHQATGKKAITHTHEEIEKKKRKETTEVMDPGREIARRARNESQRRVAMLHYLKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NM76</accession>
    <name>A0A1C7NM76_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Serine/threonine-protein phosphatase</fullName>
            <ecNumber evidence="7">3.1.3.16</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">pzh1_0</name>
        <name evidence="10" type="ORF">A0J61_01841</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:47004"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="EC" id="3.1.3.16"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the PPP phosphatase family. PP-Z subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.16" evidence="7"/>
    <dbReference type="EMBL" id="LUGH01000063">
        <property type="protein sequence ID" value="OBZ90118.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NM76"/>
    <dbReference type="FunCoup" id="A0A1C7NM76">
        <property type="interactions" value="266"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NM76"/>
    <dbReference type="InParanoid" id="A0A1C7NM76"/>
    <dbReference type="OrthoDB" id="1930084at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000324">
        <property type="term" value="C:fungal-type vacuole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004722">
        <property type="term" value="F:protein serine/threonine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008104">
        <property type="term" value="P:intracellular protein localization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006883">
        <property type="term" value="P:intracellular sodium ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.21.10:FF:000006">
        <property type="entry name" value="Serine/threonine-protein phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050341">
        <property type="entry name" value="PP1_catalytic_subunit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011159">
        <property type="entry name" value="PPPtase_PPZ/Ppq1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006186">
        <property type="entry name" value="Ser/Thr-sp_prot-phosphatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031675">
        <property type="entry name" value="STPPase_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11668">
        <property type="entry name" value="SERINE/THREONINE PROTEIN PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11668:SF484">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN PHOSPHATASE PP-Z1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16891">
        <property type="entry name" value="STPPase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000909">
        <property type="entry name" value="PPPtase_PPZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00114">
        <property type="entry name" value="STPHPHTASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00156">
        <property type="entry name" value="PP2Ac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="Metallo-dependent phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00125">
        <property type="entry name" value="SER_THR_PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0464">Manganese</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0904">Protein phosphatase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Serine/threonine specific protein phosphatases" evidence="9">
        <location>
            <begin position="258"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="9"/>
            <end position="19"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00029458"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU004273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS00125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OBZ90118.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="453" mass="51322" checksum="42B88BCDE3EBC62C" modified="2016-11-30" version="1">MGNNVSTKRNAKKERRANKSKSMPLPPRIEVTENEHSTNTAHSVNSILLTSKKNNTVTNNTLAQLNPDYPLPNNNNEDTLPRGTDPFQGKVENLHQHKLLAASDFWPPQQQQQQQVEDYNQLTVGSLNQLTVNSMASDYSSTTNIDDYINRLLEAGYASKVSKQLCLKNSEVTAICRAAMDIFLSQPSLLELSPPVKVVGDTHGQYTDLIRLFEMGGFPPTSNYLFLGDYVDRGKQSLENMLLLFCYKIKYPENFFLLRGNHECANVTKVYGFYDECKRRLSPKMWRTFVDVFNTLPIAALVAGKIFCVHGGLSPSLHSMDDIRQIQRPTDVPDYGLLNDLLWSDPADIEGDWEDNERGVSYVFGKKIINEFLAKYDLDLVCRAHMVVEDGYEFFSNRSLVTVFSAPNYCGEFDNFGAIMSVNEDLLCSFELLTPADHPLAKERLRQTKNTKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NM82</accession>
    <name>A0A1C7NM82_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Major facilitator superfamily associated domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">A0J61_01695</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. MFSD6 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000057">
        <property type="protein sequence ID" value="OBZ90241.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NM82"/>
    <dbReference type="STRING" id="101091.A0A1C7NM82"/>
    <dbReference type="InParanoid" id="A0A1C7NM82"/>
    <dbReference type="OrthoDB" id="2286425at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024989">
        <property type="entry name" value="MFS_assoc_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051717">
        <property type="entry name" value="MFS_MFSD6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16172">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN 6-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16172:SF41">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN 6-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12832">
        <property type="entry name" value="MFS_1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="24"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="58"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="84"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="128"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="150"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="332"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="360"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="391"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="423"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="465"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="496"/>
            <end position="515"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily associated" evidence="7">
        <location>
            <begin position="3"/>
            <end position="488"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF12832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OBZ90241.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="523" mass="57936" checksum="5DA21A5C3D6EC585" modified="2016-11-30" version="1" fragment="single">AHAATTSIHPYLCLYYLHRLGFDFLAISLLTAFVMLLKLPASAFWIDLVDHRPSLHGVLTGLLTAIGTAGILLTLSVPPTWTPFLLPIVMIACILDGLFYQPLEVLIDSAIIKILGDYKILYANERQYGKIISAFMAIGIGWSLDDDHDFDTLMVTLLIGSVILFLLSLSTTVQPADPTLLGILPDEQSPFLKQTENHHYKPYSLFKEHLSHISEEDPSLLQRMATNHSMITKALPRPISLSSELSYATLPIQSPSAMRVPRVDSDAKSLQPIQPTVHQLLDDHLPPSFELARLPYPPPQAPAIVLITLMPGYSHCPEMNCRHPSKWIVRSFASSIFCLGIVYGMTQPLLYLYLHDTLGFPMHTLGLMGCVTMMADYLANYLVLKVIHYGHLPVMIASAHLVLTLCTLSYTQLQPGGAPSTQLWAIVLQSLFALAMHSIWLIAAHQVDSVVLIGHERMMLKGTMAACYSSLGPTLGLLLTGYLVQIQHDDTTLHGYYFVYPYAALLSLISGILSWEWSASHCI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NMD9</accession>
    <name>A0A1C7NMD9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Putative formaldehyde dehydrogenase AdhA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">adhA_0</name>
        <name evidence="8" type="ORF">A0J61_01666</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 5">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the zinc-containing alcohol dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000056">
        <property type="protein sequence ID" value="OBZ90282.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NMD9"/>
    <dbReference type="FunCoup" id="A0A1C7NMD9">
        <property type="interactions" value="328"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NMD9"/>
    <dbReference type="InParanoid" id="A0A1C7NMD9"/>
    <dbReference type="OrthoDB" id="1879366at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016616">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05283">
        <property type="entry name" value="CAD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000022">
        <property type="entry name" value="Cinnamyl alcohol dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002328">
        <property type="entry name" value="ADH_Zn_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047109">
        <property type="entry name" value="CAD-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42683">
        <property type="entry name" value="ALDEHYDE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00059">
        <property type="entry name" value="ADH_ZINC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Alcohol dehydrogenase-like N-terminal" evidence="7">
        <location>
            <begin position="3"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="domain" description="Alcohol dehydrogenase-like C-terminal" evidence="6">
        <location>
            <begin position="132"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU361277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00107"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF08240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OBZ90282.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="292" mass="32102" checksum="3AB3E499AC317F75" modified="2016-11-30" version="1" fragment="single">PTDYPCVVGHEIVGVVTRVGKNVTNLKVGDRAGVGAQCHSCHKCQNCLDGCENNCSAGFKGTYNSNWDNGDKTYGGYADKWRGDYRFAFKVPDNLPSEVAATFFCAGVTTYAPLRRTNVNEKSVVGVMGIGGLGHYAILWAKAMGAKVVGMSSSDRKREIATQLGCDEYINTSDEKALAAYKDTFTHILCTGCGEDFTWEKYLTLIQPHGHFINVNAPDWKFPPLNPLLLIMTQVSISGSLIGSPKEIEEMLAFAAEKNIRPWITVLPMKDVNKAIEDFNAGKPRFRFVLEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NMX6</accession>
    <name>A0A1C7NMX6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Pre-mRNA-processing-splicing factor 8</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">Prpf8</name>
        <name evidence="10" type="ORF">A0J61_02113</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000076">
        <property type="protein sequence ID" value="OBZ89836.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="FunCoup" id="A0A1C7NMX6">
        <property type="interactions" value="1171"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NMX6"/>
    <dbReference type="InParanoid" id="A0A1C7NMX6"/>
    <dbReference type="OrthoDB" id="1931567at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071013">
        <property type="term" value="C:catalytic step 2 spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005682">
        <property type="term" value="C:U5 snRNP"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008237">
        <property type="term" value="F:metallopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097157">
        <property type="term" value="F:pre-mRNA intronic binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030619">
        <property type="term" value="F:U1 snRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030620">
        <property type="term" value="F:U2 snRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030623">
        <property type="term" value="F:U5 snRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017070">
        <property type="term" value="F:U6 snRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000244">
        <property type="term" value="P:spliceosomal tri-snRNP complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd08056">
        <property type="entry name" value="MPN_PRP8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd13838">
        <property type="entry name" value="RNase_H_like_Prp8_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.80.40:FF:000001">
        <property type="entry name" value="Pre-mRNA-processing-splicing factor 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.230:FF:000003">
        <property type="entry name" value="Pre-mRNA-processing-splicing factor 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.43.40:FF:000001">
        <property type="entry name" value="Pre-mRNA-processing-splicing factor 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.140.10:FF:000002">
        <property type="entry name" value="Pre-mRNA-processing-splicing factor 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.1570.40:FF:000001">
        <property type="entry name" value="Pre-mRNA-processing-splicing factor 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.80.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.230">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1570.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.140.10">
        <property type="entry name" value="Cytidine Deaminase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.43.40">
        <property type="entry name" value="Pre-mRNA-processing-splicing factor 8, U5-snRNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000555">
        <property type="entry name" value="JAMM/MPN+_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037518">
        <property type="entry name" value="MPN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012591">
        <property type="entry name" value="PRO8NT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012592">
        <property type="entry name" value="PROCN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012984">
        <property type="entry name" value="PROCT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027652">
        <property type="entry name" value="PRP8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021983">
        <property type="entry name" value="PRP8_domainIV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043173">
        <property type="entry name" value="Prp8_domainIV_fingers"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043172">
        <property type="entry name" value="Prp8_domainIV_palm"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019581">
        <property type="entry name" value="Prp8_U5-snRNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042516">
        <property type="entry name" value="Prp8_U5-snRNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019580">
        <property type="entry name" value="Prp8_U6-snRNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019582">
        <property type="entry name" value="RRM_spliceosomal_PrP8"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11140">
        <property type="entry name" value="PRE-MRNA SPLICING FACTOR PRP8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11140:SF0">
        <property type="entry name" value="PRE-MRNA-PROCESSING-SPLICING FACTOR 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01398">
        <property type="entry name" value="JAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08082">
        <property type="entry name" value="PRO8NT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08083">
        <property type="entry name" value="PROCN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08084">
        <property type="entry name" value="PROCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12134">
        <property type="entry name" value="PRP8_domainIV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10598">
        <property type="entry name" value="RRM_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10597">
        <property type="entry name" value="U5_2-snRNA_bdg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10596">
        <property type="entry name" value="U6-snRNA_bdg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00232">
        <property type="entry name" value="JAB_MPN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50249">
        <property type="entry name" value="MPN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="5" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3" id="KW-0747">Spliceosome</keyword>
    <feature type="domain" description="MPN" evidence="9">
        <location>
            <begin position="2121"/>
            <end position="2252"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="23"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="33"/>
            <end position="43"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OBZ89836.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="2351" mass="274304" checksum="F3DB9EA285E871AD" modified="2016-11-30" version="1">MASNEHEMPVPVGGAPSAYSNQYDQYAYEANPETEKSHEDKLKEKARKWQQLQNKRYGEKRKFGFIEHEKAEMPPEHLRKIIKDHGDMTAKKFRHDKRIYLGALKYVPHAVLKLLENMPMPWEQVREVNVLYHITGAITFVNEIPWVIEPVYIAQWGSMWIMMRREKRDRRHFKRMRFPPFDDEEPPLDYGDNIMDVEPLEAIQMELDEEEDDAIFDWFYDNKPLMDTKFVNGPTYRQWRLNLPIMSTLYRIANQLLSDLNDKNYFYLFDLNSFFTAKALSMAIPGGPKFEPLYRDMDTADDDWNEFNDINKIIIRQPVRTEYKIAFPFLYNSLPRSVKVSWYHYPAVVYVKSEDPDLPAYYFDPIINPISSRTIDGAGTRHEDEIFGDEEEDTEFTLPTEVVPFLDDTELYTENTSNAIALYWAPHPFDKRSGRTRRAQDVPLVKSWYLEHCPAGQPVKVRVSYQKLLKCYVLNALHHRPPKALNKKYLFRSLKATKFFQTTQIDWVEAGLQVCRQGYNMLNLLIHRKNLNYLHLDYNFNLKPVKTLTTKERKKSRFGNAFHLCREILRLTKLIVDSHVQYRLGNVDAFQLADGLQYIFAHVGQLTGMYRYKYRLMRQIRMCKDLKHLIYYRFNTGPVGKGPGVGIWAPGWRVWLFFMRGIVPLLERWLGNLLARQFEGRHSKGIAKTVTKQRVDSHYDLELRAAVLHDIMDAMPEGVKGNKSRTILQHLSEAWRAWKANIPWKVPGMPAPIENMILRYIKAKADWWTSVAHYNRERIRRGATVDKTICRKNLGRLTRLWLKAEQERQHNYLKDGPYITAEEAVAIYTSTVHWLESRKFSPIPFPPLSYKHDTKLLILALERLREAYSVQGRLNQSQREELGLIEQAYDNPHEALSRIKRLLLTQRAFKEVGIEFMDLYSHLIPVYDIEPLEKITDAYLDQYLWYEADKRHLFPAWIKPSDSEPPPLLVYKWCQGINNLTDVWDTTEGQCNVMMETSFSRVYEKIDLTLLGRLLRLILDHNLADYATAKNNVVLSYKDMNHVNAFGLIRGLQFASFIFQYYGLVLDLLVLGLHRASEMAGPPQLPNDFLQYRDVDTETRHPIRLYSRYIDRIHIFFRFTADEARDLIQRYLTEHPDPNFENIVGYNNKKCWPRDCRMRLMKHDVNLGRAVFWDIKNRLPRSLTTIEWDTSFVSVYSKDNPNLLFSMCGFEVRILPKIRSMNEEFTLRDGVWNLVNEQTKERTAQAYLRVDQESMDRFHNRIRQILMASGSTTFSKIANKWNTALIGLMTYYREAVVHTRELLDLLVKCENKIQTRVKIGLNSKMPSRFPPVVFMTPKELGGLGMLSMGHILIPQSDLRWSKQTDTGITHFRSGMSHDEDALIPNLYRYIQSWESEFVDSQRVWAEYALKRQEANAQNRRLTLEDLEDSWDRGIPRINTLFQKDRHTLAYDKGWRVRTDFKQYQVLKNNPFWWTHQRHDGKLWNLNNYRTDMIQALGGIESILEHTLFKALGYTSWEGLFWEKASGFEASMQTKKLTNAQRSGLNQIPNRRFTLWFSPTINRSNVYVGFQVQLDLTGIFMHGKIPTLKISLIQIFRAHLWQKIHEALTMDFAQVFDRELEALQIETVQKETIHPRKSYKMNSSASDILLFAAYKWPVSRPSLLNDPKDVMDGPTTTKYWLDIQLRWGDFDSHDIERYTRAKFLDYTTDNMSIYPSPTGLMVGIDLAYNMYSAYGNWIPGMKPLVQQAMSKIMKANPALYVLRERIRKALQLYSSEPTEPYLSSTNYGELFSNQIIWFVDDTNVYRVTIHKTFEGNLTTKPINGAIFIFNPRTGQLFLKIIHTSVWAGQKRLGQLAKWKTAEEVAALIRSLPVEEQPKQIIVTRKGMLDPLEVHLLDFPNIVIKGSELQLPFQACLKVEKFGDLILKATEPQMVLFNLYDDWLKSFSSYTAFSRLVLILRALHVNTEKTKLILRPDRSTITEPHHIWPTLSDEEWAKVEVQLKDLILADYGKKNNVNVASLTQSEIRDIILGMEIQAPSLQRQQIAEIEKQTKEQSQLTAVTTKTRNIHGDEIVVTTTSNYEQATFSSKTEWRIRAISATNLHLRTNHIYVNSDDIHENTYTYVMPKNVLKRFITISDLRTQIAGFLYGVSPPDAPNVKEIRCIVIPPQWGTHQTVHLPSTFPEHEYLNDLEPLGWIHTQPQELMNISPQDVTTHAKMLAGNRAWDGEKTITLTCSFTPGSCSLTAYKLSPAGFEWGKNNVDPGSQPQGYLPTHGEKVQILLSDRFLGHFMVPSETWNYNFMGAQFSANMNYRLVLDVPKEFYHESHRAAHFMNFSSETEATTEADIEDAFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-06-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NMY0</accession>
    <name>A0A1C7NMY0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_03338</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000141">
        <property type="protein sequence ID" value="OBZ88624.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NMY0"/>
    <dbReference type="InParanoid" id="A0A1C7NMY0"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ88624.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="68" mass="7732" checksum="76C8C2E6598A9FFB" modified="2016-11-30" version="1">MAGSYQCDKPGRSQSTNDYGCSIWKHKNSSDLKFPRHHFKVAFATFVKNNFAPLTSFGMTVLVLENQF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NNC5</accession>
    <name>A0A1C7NNC5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Tropomyosin-2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_01369</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000042">
        <property type="protein sequence ID" value="OBZ90587.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NNC5"/>
    <dbReference type="STRING" id="101091.A0A1C7NNC5"/>
    <dbReference type="InParanoid" id="A0A1C7NNC5"/>
    <dbReference type="OrthoDB" id="128924at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.170">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000533">
        <property type="entry name" value="Tropomyosin"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00261">
        <property type="entry name" value="Tropomyosin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57997">
        <property type="entry name" value="Tropomyosin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="1"/>
            <end position="119"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ90587.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="141" mass="16728" checksum="F88BD45EC203453A" modified="2016-11-30" version="1">MEKVKERLASLRADAEQATALAEEFEAKIKQLELEHTNKDHELLSIQIRAKNLEEQLDKTEDALHQISAKYNEADLKAEEAEKRVQKLEQELADKEQYNEELQEKYRGIKSELDELSRQFEELYKYYQVLLSLYEVDFYPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NNW7</accession>
    <name>A0A1C7NNW7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">ATP synthase subunit 4</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">atp-3_0</name>
        <name evidence="9" type="ORF">A0J61_01260</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Subunit b, of the mitochondrial membrane ATP synthase complex (F(1)F(0) ATP synthase or Complex V) that produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. ATP synthase complex consist of a soluble F(1) head domain - the catalytic core - and a membrane F(1) domain - the membrane proton channel. These two domains are linked by a central stalk rotating inside the F(1) region and a stationary peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. In vivo, can only synthesize ATP although its ATP hydrolase activity can be activated artificially in vitro. Part of the complex F(0) domain. Part of the complex F(0) domain and the peripheric stalk, which acts as a stator to hold the catalytic alpha(3)beta(3) subcomplex and subunit a/ATP6 static relative to the rotary elements.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. In yeast, the dimeric form of ATP synthase consists of 17 polypeptides: alpha, beta, gamma, delta, epsilon, 4 (B), 5 (OSCP), 6 (A), 8, 9 (C), d, E (Tim11), f, g, h, i/j and k.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Mitochondrion</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="8">Mitochondrion inner membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the eukaryotic ATPase B chain family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000038">
        <property type="protein sequence ID" value="OBZ90670.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NNW7"/>
    <dbReference type="FunCoup" id="A0A1C7NNW7">
        <property type="interactions" value="107"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NNW7"/>
    <dbReference type="InParanoid" id="A0A1C7NNW7"/>
    <dbReference type="OrthoDB" id="67388at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045259">
        <property type="term" value="C:proton-transporting ATP synthase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046933">
        <property type="term" value="F:proton-transporting ATP synthase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.2210">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008688">
        <property type="entry name" value="ATP_synth_Bsub_B/MI25"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013837">
        <property type="entry name" value="ATP_synth_F0_suB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12733:SF3">
        <property type="entry name" value="ATP SYNTHASE F(0) COMPLEX SUBUNIT B1, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12733">
        <property type="entry name" value="MITOCHONDRIAL ATP SYNTHASE B CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05405">
        <property type="entry name" value="Mt_ATP-synt_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161060">
        <property type="entry name" value="ATP synthase B chain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 8" id="KW-0138">CF(0)</keyword>
    <keyword evidence="3 8" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="5 8" id="KW-0406">Ion transport</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="6 8" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="4 8" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 8" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022547"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU368017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OBZ90670.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="241" mass="26880" checksum="D302B9F801F5CF9F" modified="2016-11-30" version="1">MAFRLITKNATAAALARPAMLSASRQSLGAAAVRHYTTQKEVEPKEKANSIINALPGNSLVSKTGYLTLGTGIATFMISKEIYVFNEETLVLVASTGLLGLLLKYLREPFTNMANEHIERIKNVLVQARDDHKTAVKERINEVGQMKDLVDVTKALFELSRETAKLEAEAFTLKQQVAVANEVKATLDSWVRHEANVREREQKQLAAHLIEKINKDLQDPKIQQQILEQAIVDVQKIAKTH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NNY8</accession>
    <name>A0A1C7NNY8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Cytosol aminopeptidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">lap_0</name>
        <name evidence="6" type="ORF">A0J61_01357</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase M17 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000042">
        <property type="protein sequence ID" value="OBZ90599.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NNY8"/>
    <dbReference type="FunCoup" id="A0A1C7NNY8">
        <property type="interactions" value="446"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NNY8"/>
    <dbReference type="InParanoid" id="A0A1C7NNY8"/>
    <dbReference type="OrthoDB" id="412814at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030145">
        <property type="term" value="F:manganese ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070006">
        <property type="term" value="F:metalloaminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00433">
        <property type="entry name" value="Peptidase_M17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.220.10">
        <property type="entry name" value="Leucine Aminopeptidase, subunit E, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.10">
        <property type="entry name" value="Zn peptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011356">
        <property type="entry name" value="Leucine_aapep/pepB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043472">
        <property type="entry name" value="Macro_dom-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000819">
        <property type="entry name" value="Peptidase_M17_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008283">
        <property type="entry name" value="Peptidase_M17_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11963:SF23">
        <property type="entry name" value="CYTOSOL AMINOPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11963">
        <property type="entry name" value="LEUCINE AMINOPEPTIDASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00883">
        <property type="entry name" value="Peptidase_M17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02789">
        <property type="entry name" value="Peptidase_M17_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00481">
        <property type="entry name" value="LAMNOPPTDASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52949">
        <property type="entry name" value="Macro domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53187">
        <property type="entry name" value="Zn-dependent exopeptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00631">
        <property type="entry name" value="CYTOSOL_AP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 6" id="KW-0031">Aminopeptidase</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cytosol aminopeptidase" evidence="5">
        <location>
            <begin position="349"/>
            <end position="356"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS00631"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OBZ90599.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="491" mass="53375" checksum="ECC1E6815C17AB84" modified="2016-11-30" version="1">MLLLTRKSLIKAAKIPSPHRFFSNKQGFDSLVIGAYSAKEPLLTTQHVSQQTRDLIQRQLATSNFKKLGDTRIFYNLDGIGQVAVVSLGEKQQDGPKRQENVRMATAIGIQALQKQNAIYTGVDVSVDVQGAAEGTVLAQFSFDKLKQKKLEDQVDRVVEPYMPESSKAIQDAWEVGQICGASQNVARMLMTSPANLMTPKLFADEVAYLLAGLENIDIHVRNEEWAKKQKMNAFLSVSRGSTEPLRFLEIHYNGAKDSQQKPYGLVGKGVTFDTGGISLKPSANMASMKGDMGGAATVAGALYGISKLKLPVNIIAMIPLCENMPSGVATKPGDVFKAMNGKSIEVLNTDAEGRLILADALHYLSSQFEPQYIIDLATLTGAMDVALGQVFAGVFTNSDSLWEELESAGKAVSDRFWRMPLHSDYVKDMKQSLVADLSNVGLRRSGGSCAAAGFLQEFVDKNTPWAHIDIAGVMECHSTKGHHIKGMSGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NP88</accession>
    <name>A0A1C7NP88_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">U3 small nucleolar RNA-interacting protein 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">RRP9</name>
        <name evidence="7" type="ORF">A0J61_01682</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000056">
        <property type="protein sequence ID" value="OBZ90276.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NP88"/>
    <dbReference type="FunCoup" id="A0A1C7NP88">
        <property type="interactions" value="698"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NP88"/>
    <dbReference type="InParanoid" id="A0A1C7NP88"/>
    <dbReference type="OrthoDB" id="189968at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031428">
        <property type="term" value="C:box C/D methylation guide snoRNP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032040">
        <property type="term" value="C:small-subunit processome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034511">
        <property type="term" value="F:U3 snoRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000480">
        <property type="term" value="P:endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000447">
        <property type="term" value="P:endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000472">
        <property type="term" value="P:endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.10:FF:000509">
        <property type="entry name" value="U3 small nucleolar RNA-interacting protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039241">
        <property type="entry name" value="Rrp9-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19865">
        <property type="entry name" value="U3 SMALL NUCLEOLAR RNA INTERACTING PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19865:SF0">
        <property type="entry name" value="U3 SMALL NUCLEOLAR RNA-INTERACTING PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 5" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="137"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="189"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="231"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="273"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="391"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="18"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="38"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="56"/>
            <end position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OBZ90276.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="482" mass="54174" checksum="69C384489F09A56E" modified="2016-11-30" version="1">MAVDSFFASARKRKRPTKTTSMSGKKTNGIKQKKQDSDLEEDEEEDQFNANLSAESEAESSEEELVETAAEKRVRLAKAYLNKIEDSLEDGDGFDAADLDRDLIAERLKKDDDESEGRLHLRIADTFKWDSLDLHTNRGHQLPVTAVALAENGSVYYSASKDGSIVKWDLSTKKRLHTFPGGRKGVKNFDGHTDHILCLAISHDGKYLVSGGKDKSINLWSVTEDKHLAKFTQHRDTVSGLAFRKGQNQLYSASHDRTIKLWNIDERAYIETLFGHQDQITDIDTLVRERCVSTGGRDKTARVWKIVEESQLVYRGGVSSKKEGETLYVEGSLDCIAQIDESMFVTGGDSGVISLWELNRKKPVYSMSSAHGLQDEKSPYWITAVASLRYSDLFVSGSWDGYVRVWKLSSDNKQFSQIATIAVEGVVNSIQIKTVFPSNRTWIIVGVGQELKLGRWIRMKKGVKNCTKVIELERASSSFRII</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NPU7</accession>
    <name>A0A1C7NPU7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_00940</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000025">
        <property type="protein sequence ID" value="OBZ91010.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NPU7"/>
    <dbReference type="InParanoid" id="A0A1C7NPU7"/>
    <dbReference type="OrthoDB" id="2276649at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ91010.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="110" mass="11877" checksum="BFB06A303235B4F6" modified="2016-11-30" version="1">MSSNSQKAAQKTDKVANQVSSGAHEAANKVDQVLDNAPEKAAKATQIAEDEVNRLKAELADLKQKAGPKIQEAENMLTSPAAINFYKGLITGVALVLAYNRYTTTYVRLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NQD1</accession>
    <name>A0A1C7NQD1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_00656</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000015">
        <property type="protein sequence ID" value="OBZ91313.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NQD1"/>
    <dbReference type="InParanoid" id="A0A1C7NQD1"/>
    <dbReference type="OrthoDB" id="2387215at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008889832" evidence="1">
        <location>
            <begin position="21"/>
            <end position="143"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ91313.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="143" mass="15682" checksum="BDB179C813241B41" modified="2016-11-30" version="1">MKFSTLLLAALAFFCSLAFSASIPYSDLSDDQVARLYVSKVSEIDTQNNIEYPPANTTWYVGESVNVTFKDTASANETVAIFFFNQSPLLAGGPLTTKVFPFVVPQEAVSPEDGTSLLLAVRRKNYYLQTVDSVVVRVLPARS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NQT4</accession>
    <name>A0A1C7NQT4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">THP3 C2A9.11c</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_00674</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000016">
        <property type="protein sequence ID" value="OBZ91279.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NQT4"/>
    <dbReference type="STRING" id="101091.A0A1C7NQT4"/>
    <dbReference type="InParanoid" id="A0A1C7NQT4"/>
    <dbReference type="OrthoDB" id="199574at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.990">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000717">
        <property type="entry name" value="PCI_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045107">
        <property type="entry name" value="SAC3/GANP/THP3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005062">
        <property type="entry name" value="SAC3/GANP/THP3_conserved"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12436">
        <property type="entry name" value="80 KDA MCM3-ASSOCIATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12436:SF4">
        <property type="entry name" value="LEUKOCYTE RECEPTOR CLUSTER MEMBER 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03399">
        <property type="entry name" value="SAC3_GANP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50250">
        <property type="entry name" value="PCI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PCI" evidence="1">
        <location>
            <begin position="260"/>
            <end position="430"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50250"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ91279.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="442" mass="50302" checksum="E824A94CDB0D6BEC" modified="2016-11-30" version="1">MSKKQPQYIPVKVGNKKKSVAVNQTPGIKLGTLKAAASEQPLPQSLQEYVQHAMENCLPESKPLVEMQLKKIITQAKNTDMLNVIDWNERDLPSACIDTKNPNSLSLFHKKPATIVSKLGNIELTPAEEKRRQLRALRFQNDTATAPPPLKKKNKKNITPIVWNDNGNDLDEVIIGTSTNLEKPYFRLTSAADPATVRPLNVLKKTYKMLRTKWKTEANYSYICEQFKSMRQDLTVQRIRNEFTVMVYETHARIALEKGDIGEYNQCQTQLKYLYEQGISGCEDEFTAYRILYLIFSQNQSDINSMLEEMCDIGLENHASCVQHALMVRTSLAKGNYHKFFQLYEEAPNMGGYLLDQFVGRVRIDALLVMCKAYKLGVPLSYIAQELSFKSIKKLVQFLREHGIRVIPSKDKSAPLFDTKSALPILIAQSKSYNKVDIKGQI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NR54</accession>
    <name>A0A1C7NR54_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_00524</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000012">
        <property type="protein sequence ID" value="OBZ91399.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NR54"/>
    <dbReference type="STRING" id="101091.A0A1C7NR54"/>
    <dbReference type="InParanoid" id="A0A1C7NR54"/>
    <dbReference type="OrthoDB" id="2226733at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ91399.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="464" mass="53224" checksum="4300573AD73209AD" modified="2016-11-30" version="1">MSFFPHGDFATQHEAVRNAFRIALETKRTLILPHIRLGRKEIPWAPFPVLQKYYEAQDKDVLKLACAKKHENWYTQYQPCRDLNQWVELPWSSLFDLKAVTDQFDIRIIERSWDRGWGVNEGKLSHIGLTQDDVVVVDANSFPSNGSDWELKQQISVINLAEETEQSMKLKSPLKNLVTSDQLLKLKQKYIQFGSLVFGLRYQTTLTKQQVALQKALRSTLFTSPNQYNTLNTIAHSIVQALGGAGKFNVIHMNLETIVKVELQNRASMNRENAEIEGKPFTDKTAYFDSNGVPLRGSELLKQLGHQDQSELMSAVVRELQGDMPINQAVSAALPFRPSLLKDFLSVSSVKEQRRDLLSACIDYHATVDQRYPIYFLTNDIYSDIFTHPELFGPFTKAFPCTFTKQDVYEWGVVNPKWANQINLLQDVDYEDILSPIIEILVAKEAYSFFEVPTTKLTRLLSWH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NRE4</accession>
    <name>A0A1C7NRE4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 8">Malate synthase</fullName>
            <ecNumber evidence="2 8">2.3.3.9</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">acu-9</name>
        <name evidence="12" type="ORF">A0J61_00421</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6 8">
            <text>glyoxylate + acetyl-CoA + H2O = (S)-malate + CoA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:18181"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15589"/>
            <dbReference type="ChEBI" id="CHEBI:36655"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="EC" id="2.3.3.9"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="8">Carbohydrate metabolism; glyoxylate cycle; (S)-malate from isocitrate: step 2/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 8">Belongs to the malate synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.3.9" evidence="2 8"/>
    <dbReference type="EMBL" id="LUGH01000009">
        <property type="protein sequence ID" value="OBZ91530.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NRE4"/>
    <dbReference type="STRING" id="101091.A0A1C7NRE4"/>
    <dbReference type="InParanoid" id="A0A1C7NRE4"/>
    <dbReference type="OrthoDB" id="186072at2759"/>
    <dbReference type="UniPathway" id="UPA00703">
        <property type="reaction ID" value="UER00720"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005782">
        <property type="term" value="C:peroxisomal matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004474">
        <property type="term" value="F:malate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006097">
        <property type="term" value="P:glyoxylate cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00727">
        <property type="entry name" value="malate_synt_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1220.12:FF:000001">
        <property type="entry name" value="Malate synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.360:FF:000001">
        <property type="entry name" value="Malate synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.360">
        <property type="entry name" value="Malate synthase, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1220.12">
        <property type="entry name" value="Malate synthase, domain III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044856">
        <property type="entry name" value="Malate_synth_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011076">
        <property type="entry name" value="Malate_synth_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006252">
        <property type="entry name" value="Malate_synthA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019830">
        <property type="entry name" value="Malate_synthase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001465">
        <property type="entry name" value="Malate_synthase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048355">
        <property type="entry name" value="MS_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048356">
        <property type="entry name" value="MS_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046363">
        <property type="entry name" value="MS_N_TIM-barrel_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01344">
        <property type="entry name" value="malate_syn_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42902">
        <property type="entry name" value="MALATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42902:SF1">
        <property type="entry name" value="MALATE SYNTHASE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20659">
        <property type="entry name" value="MS_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20656">
        <property type="entry name" value="MS_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01274">
        <property type="entry name" value="MS_TIM-barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001363">
        <property type="entry name" value="Malate_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51645">
        <property type="entry name" value="Malate synthase G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00510">
        <property type="entry name" value="MALATE_SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 8" id="KW-0329">Glyoxylate bypass</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 8" id="KW-0816">Tricarboxylic acid cycle</keyword>
    <feature type="domain" description="Malate synthase N-terminal" evidence="10">
        <location>
            <begin position="19"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="domain" description="Malate synthase TIM barrel" evidence="9">
        <location>
            <begin position="174"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="domain" description="Malate synthase C-terminal" evidence="11">
        <location>
            <begin position="425"/>
            <end position="544"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="7">
        <location>
            <position position="178"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="7">
        <location>
            <position position="459"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006394"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022435"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00047918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR001363-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF20656"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF20659"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="OBZ91530.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="553" mass="62588" checksum="F77E99F71D9A7B81" modified="2016-11-30" version="1">MSAVTSRSSAKLIKTSVPGVAVLAPVTASEADILSPQALQFVATLQRIFNPTRKTLMQKRALRQQELDRGVLPNFLPETAYIRDDPNWRAAPPAPGLQDRRVEITGPVDRKMVINALNSGAFTFMADFEDSTSPTWENIISGQVNLRDAVRESIEFTNPNGKKYALRKDGKIATLLVRPRGWHMVEKHVLVDGEPCSASIFDFALYFFHNAKELVKRGKGPYFYLPKMESHLEARLWNDIFNVAQDMINIPRGTIRGTVLIETLLAAYEMDEIIYELRDHSSGLNCGRWDYIFSFIKKLRNHPQFVLPQRSQVTMTVPFMDAYVRLLIQTCHKRGVHAMGGMAAQIPIKNNPEANEAAMAKVRSDKLREVTAGHDGTWVAHPDLVKIALDIFNEHMPQPNQLHIRRDDVKVTATDLIDINFKGTITEDSIRENIQIGLAYMEAWLRGVGCVPIFNLMEDLATYEISRSQLYQWVHHQVRTNEGKTVTSEYVGNILNEEVEKIRKNLGNDKFSQSKYEAAKKAFATNVTGERYDDFLPDLLYDDIVSASAHSKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NRT9</accession>
    <name>A0A1C7NRT9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">SAP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_00088</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000002">
        <property type="protein sequence ID" value="OBZ91841.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NRT9"/>
    <dbReference type="STRING" id="101091.A0A1C7NRT9"/>
    <dbReference type="InParanoid" id="A0A1C7NRT9"/>
    <dbReference type="OrthoDB" id="445357at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.720.30">
        <property type="entry name" value="SAP domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003034">
        <property type="entry name" value="SAP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036361">
        <property type="entry name" value="SAP_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02037">
        <property type="entry name" value="SAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00513">
        <property type="entry name" value="SAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF68906">
        <property type="entry name" value="SAP domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50800">
        <property type="entry name" value="SAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SAP" evidence="2">
        <location>
            <begin position="289"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="120"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="194"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="124"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="196"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="213"/>
            <end position="224"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50800"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ91841.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="495" mass="56012" checksum="6E18C91119D4D6D7" modified="2016-11-30" version="1">MDESTEYWRIIDYPPFFSNIDWNGNQPTSSFIPMEFDQQKIPPSYQNPPPFQRRRSSSVDLPINPLYLNSNRFMFGNTENTIHEEEQAPFKVGSSATLEFPANQPNNHAQFSYNTPANNNMFLTTAESPSLSTSSSTNNDEHMISPPLSHQGPLAPNQPMNTTSPKKPPTPPDSTTNTFFPELHRTSYNTILGKQLRQHQKRRRSSSLPPAFHTTNKNVNSKGPTPLIFTQIQVTDPTPIQHTQKAAKVDARPIAIERVHKKPQMAKPMDIDPIETQKKLDEQLLQLNFDDVTVAELKEMLKERGLSSTGKKAVLSDRLKEVRDQLIAKRQPIKQEEEEKVKWAEPKEAPWTIPSEETKPNPTWISPPIKMETITASPAIQGIADMSIHSPAPPPVKMSFSPVAQPVNTQPTPPSDAALFPQDYSYPPPSQPMIQEPNDLNMNGLFDFDTLLDGNAILFPPTQSSPQRQNEDHIQHDWDINWDQDKLDHFLTELV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NS40</accession>
    <name>A0A1C7NS40_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Elongation of fatty acids protein</fullName>
            <ecNumber evidence="10">2.3.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">ELO1</name>
        <name evidence="11" type="ORF">A0J61_00160</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>an acyl-CoA + malonyl-CoA + H(+) = a 3-oxoacyl-CoA + CO2 + CoA</text>
            <dbReference type="Rhea" id="RHEA:50252"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57384"/>
            <dbReference type="ChEBI" id="CHEBI:58342"/>
            <dbReference type="ChEBI" id="CHEBI:90726"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="10">
            <dbReference type="Rhea" id="RHEA:50253"/>
        </physiologicalReaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the ELO family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.-" evidence="10"/>
    <dbReference type="EMBL" id="LUGH01000003">
        <property type="protein sequence ID" value="OBZ91790.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NS40"/>
    <dbReference type="STRING" id="101091.A0A1C7NS40"/>
    <dbReference type="InParanoid" id="A0A1C7NS40"/>
    <dbReference type="OrthoDB" id="10259681at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009922">
        <property type="term" value="F:fatty acid elongase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034625">
        <property type="term" value="P:fatty acid elongation, monounsaturated fatty acid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034626">
        <property type="term" value="P:fatty acid elongation, polyunsaturated fatty acid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019367">
        <property type="term" value="P:fatty acid elongation, saturated fatty acid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030148">
        <property type="term" value="P:sphingolipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042761">
        <property type="term" value="P:very long-chain fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002076">
        <property type="entry name" value="ELO_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11157:SF169">
        <property type="entry name" value="ELONGATION OF FATTY ACIDS PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11157">
        <property type="entry name" value="FATTY ACID ACYL TRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01151">
        <property type="entry name" value="ELO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 10" id="KW-0275">Fatty acid biosynthesis</keyword>
    <keyword evidence="5 10" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="2 10" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="7 10" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 10" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="72"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="124"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="175"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="208"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="241"/>
            <end position="261"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU361115"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="OBZ91790.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="274" mass="31284" checksum="7A805BDC6874B0D8" modified="2016-11-30" version="1">MDVDQLKPIPGIPFPEYYEFFMDWKTPVAIATIYAVTVHLLNPSAESAKLSRVEAKNRGVNNATKSSKLMTAFVFVHNLILSVYSGITFVSMAYNMHKLFNRGSSLHDAYCDMDSFLWNEGLGYWGYLFYLSKFYEVIDTAIIIMKGRRSSLLQTYHHSGAMITMWSGIRYQAQPIWIFVVFNSLIHSIMYMYYAMTSIGFHPPGKRYLTTMQISQFLIGMSTAISYLIVPNCLKSPGQQFAVGINVGYLLPLTYLFVDFARKTYGNRKAKKAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NS72</accession>
    <name>A0A1C7NS72_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Putative 4-coumarate--CoA ligase 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">4cl1_1</name>
        <name evidence="6" type="ORF">A0J61_00104</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ATP-dependent AMP-binding enzyme family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000002">
        <property type="protein sequence ID" value="OBZ91830.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NS72"/>
    <dbReference type="STRING" id="101091.A0A1C7NS72"/>
    <dbReference type="InParanoid" id="A0A1C7NS72"/>
    <dbReference type="OrthoDB" id="1898221at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016405">
        <property type="term" value="F:CoA-ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05911">
        <property type="entry name" value="Firefly_Luc_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.300.30:FF:000007">
        <property type="entry name" value="4-coumarate--CoA ligase 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.980">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.38.10">
        <property type="entry name" value="Luciferase, Domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025110">
        <property type="entry name" value="AMP-bd_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_synth/lig_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24096:SF149">
        <property type="entry name" value="AMP-BINDING DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24096">
        <property type="entry name" value="LONG-CHAIN-FATTY-ACID--COA LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13193">
        <property type="entry name" value="AMP-binding_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56801">
        <property type="entry name" value="Acetyl-CoA synthetase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 6" id="KW-0436">Ligase</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="147"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="domain" description="AMP-dependent synthetase/ligase" evidence="4">
        <location>
            <begin position="1"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="domain" description="AMP-binding enzyme C-terminal" evidence="5">
        <location>
            <begin position="357"/>
            <end position="436"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF13193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OBZ91830.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="456" mass="50046" checksum="3A205501A4F7AD4D" modified="2016-11-30" version="1">MGAVAAGGSTSPANPNYTPKELAYQLEMTKAKVLIAHPSNLPNALAAAKLVGLDKSNVFLFGTKTVDGVLPYTQVFLNKRRAQPAKLTPEQARDTVAYLCFSSGTTGKSKGVMTTHTNIISNVLQYYAMDHPFVNGQKDRMIGVLPFFHIFGLTVLLHVALYLGVPVYVMSRFELTQFCETVQNSKITFTCLVPPIILLLAKHPIVDQYDLSSLRQVICGAAPLSAELQALVNLRLPKMIVKQGYGLTETSPVAVLEPSDRVIPGSIGILVPNMTAKIVNEEGQEVKQGERGELWLKGPNVMKGYINNPEATADCIDQEGYFHTGDVAVQDEKGHFYIVDRIKELIKYKGFQVPPAELEAVLLGSPLVDDCAVIGVYDHEQATELPRGYIVLKSGVPATKETEEVIKKFVADHVVYYKQLRSVVFVQEIPKSPAGKILRRILRDAAAQEQNNKAKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NSF1</accession>
    <name>A0A1C7NSF1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Protein transport protein SFT2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">Sft2d1_1</name>
        <name evidence="9" type="ORF">A0J61_00516</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Nonessential protein required for the fusion of transport vesicles derived from the endocytic pathway with the Golgi complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Golgi apparatus membrane</location>
            <topology evidence="8">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7 8">Belongs to the SFT2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000011">
        <property type="protein sequence ID" value="OBZ91466.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NSF1"/>
    <dbReference type="STRING" id="101091.A0A1C7NSF1"/>
    <dbReference type="InParanoid" id="A0A1C7NSF1"/>
    <dbReference type="OrthoDB" id="73614at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016192">
        <property type="term" value="P:vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007305">
        <property type="entry name" value="Vesicle_transpt_Got1/SFT2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011691">
        <property type="entry name" value="Vesicle_transpt_SFT2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23137:SF6">
        <property type="entry name" value="VESICLE TRANSPORT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23137">
        <property type="entry name" value="VESICLE TRANSPORT PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04178">
        <property type="entry name" value="Got1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 8" id="KW-0653">Protein transport</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2 8" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="32"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="60"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="92"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="118"/>
            <end position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00025800"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU363111"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OBZ91466.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="157" mass="17601" checksum="7F25E95B0ADDB9EB" modified="2016-11-30" version="1">MAFGFFSSQYDDQGTMDEGNWQFFGLSKTQRLYAFGISFIAGTVLSILATIVLISSVPAFAILYSLGNIVSLLSLTFIIGLKKQFKTMFAPVRFWATVTYLGMLVLTIILSITLAKFFLSLILVIIQFSALVWYSASYIPYGREMIRRFFGSCITSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MTT2</accession>
    <name>A0A1C7MTT2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">CASTOR ACT domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_11784</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01002485">
        <property type="protein sequence ID" value="OBZ80167.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MTT2"/>
    <dbReference type="InParanoid" id="A0A1C7MTT2"/>
    <dbReference type="OrthoDB" id="58529at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006520">
        <property type="term" value="P:amino acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046394">
        <property type="term" value="P:carboxylic acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2130.10">
        <property type="entry name" value="VC0802-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045865">
        <property type="entry name" value="ACT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027795">
        <property type="entry name" value="CASTOR_ACT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051719">
        <property type="entry name" value="CASTOR_mTORC1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31131:SF6">
        <property type="entry name" value="CASTOR ACT DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31131">
        <property type="entry name" value="CHROMOSOME 1, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13840">
        <property type="entry name" value="ACT_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55021">
        <property type="entry name" value="ACT-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CASTOR ACT" evidence="1">
        <location>
            <begin position="137"/>
            <end position="195"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ80167.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="204" mass="22757" checksum="994BE0BD726EF10F" modified="2016-11-30" version="1">MEALREDGFEIESALPEIRFDLVTPHWNEDEGVLLDEGDKQPPSPIADPSRFLLATSVLVNELQCVGLNKHDRSIWVQTVLKILCYPELVQSDCGPDHKRFCSFVATSDDISIIADKQIIAFFDDSSLMQEQDAPAQKVIQVHFSGSNTDRYGIVRSISKPLSIDANINMLYLSSYMTANIIVSADDLERAVSIISPQKDLLIC</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MU38</accession>
    <name>A0A1C7MU38_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Tr-type G domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">A0J61_11608</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01002248">
        <property type="protein sequence ID" value="OBZ80343.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MU38"/>
    <dbReference type="STRING" id="101091.A0A1C7MU38"/>
    <dbReference type="InParanoid" id="A0A1C7MU38"/>
    <dbReference type="OrthoDB" id="342024at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000795">
        <property type="entry name" value="T_Tr_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050100">
        <property type="entry name" value="TRAFAC_GTPase_members"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23115">
        <property type="entry name" value="TRANSLATION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00009">
        <property type="entry name" value="GTP_EFTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tr-type G" evidence="3">
        <location>
            <begin position="5"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="49"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00009"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OBZ80343.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="49" mass="5356" checksum="D62FAF3247047A05" modified="2016-11-30" version="1" fragment="single">MGKEKTHVNVVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-06-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MU64</accession>
    <name>A0A1C7MU64_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_11571</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01002207">
        <property type="protein sequence ID" value="OBZ80380.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MU64"/>
    <dbReference type="InParanoid" id="A0A1C7MU64"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ80380.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="78" mass="9136" checksum="0378EA90DC468F03" modified="2016-11-30" version="1">MEDNTIILLTNYLISLEYPQNATKSDITYPKKNAHKFVLHDKVLYRFNPEVNAKLKKVLNKEQAIEAIETFGRKFHCP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MUP5</accession>
    <name>A0A1C7MUP5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_11355</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001943">
        <property type="protein sequence ID" value="OBZ80595.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MUP5"/>
    <dbReference type="InParanoid" id="A0A1C7MUP5"/>
    <dbReference type="OrthoDB" id="3691720at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ80595.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="84" mass="9780" checksum="D56B0A7C8215587A" modified="2016-11-30" version="1">MKQKRHVLIASILQPSGSSSSQYHLIPRIKLSTLEDWRYEVFTHGQLYVAFSRATSWKNITVLFSEDKEEETTRNIVCPELLIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MUP9</accession>
    <name>A0A1C7MUP9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_11389</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001979">
        <property type="protein sequence ID" value="OBZ80562.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MUP9"/>
    <dbReference type="STRING" id="101091.A0A1C7MUP9"/>
    <dbReference type="InParanoid" id="A0A1C7MUP9"/>
    <dbReference type="OrthoDB" id="2289697at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="187"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ80562.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="187" mass="21873" checksum="96B326A62551CF62" modified="2016-11-30" version="1" fragment="single">MIMHVFMNGDNDMISERMMKKILFLSKLVLLIAKNAFKDNRRVRLPSLNELMRYQENKRSKIPAFPSKKLEVKIKEDKKVDVFINLPSDHLQLLAANPKKATTILPVPHHTPDQSACLQQGDKWKKNKFFQQPMWTVNGVDVWSGDVVLVTDDQKDMYYILIDSLFRMQGEMFALAHHMFFSDNNNF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MUW7</accession>
    <name>A0A1C7MUW7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Clock-controlled protein 8</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">ccg-8_0</name>
        <name evidence="2" type="ORF">A0J61_11320</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001903">
        <property type="protein sequence ID" value="OBZ80632.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MUW7"/>
    <dbReference type="STRING" id="101091.A0A1C7MUW7"/>
    <dbReference type="InParanoid" id="A0A1C7MUW7"/>
    <dbReference type="OrthoDB" id="2441642at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003714">
        <property type="term" value="F:transcription corepressor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030968">
        <property type="term" value="P:endoplasmic reticulum unfolded protein response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008654">
        <property type="term" value="P:phospholipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013927">
        <property type="entry name" value="TF_Opi1_Ccg-8"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38406">
        <property type="entry name" value="TRANSCRIPTIONAL REPRESSOR OPI1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38406:SF1">
        <property type="entry name" value="TRANSCRIPTIONAL REPRESSOR OPI1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08618">
        <property type="entry name" value="Opi1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="26"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="255"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="30"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ80632.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="274" mass="30950" checksum="4673B86DDC0B2593" modified="2016-11-30" version="1" fragment="single">IAEDDDTLAATTALARASLYDSQYQDIAHQRHTNRERKSRPTSRSTSPHRPYKLVRPDQQKSRWQQLVLNASSAAGTTAAVISEESMKCLRYCLSWLRYAIMHIEQQVALLRQHLNSLFTSSSSLLTSRTELAVTEDEVIENSTLASIRREIVDTLRKVVDVVSRYAGAGLPEQAKANVRSFILELPNRWAALDQKPKQSMHREQSMHEASIRLLEFGGESIEMLKSVSTIFSDTIERAELWLKRLKVVSMHTASSQPSNFCPTSSPDTSMDMK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MVM4</accession>
    <name>A0A1C7MVM4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_11091</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001665">
        <property type="protein sequence ID" value="OBZ80860.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MVM4"/>
    <dbReference type="InParanoid" id="A0A1C7MVM4"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="33"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="59"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="103"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="65"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="127"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ80860.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="127" mass="14141" checksum="9B2A07195B152F7E" modified="2016-11-30" version="1" fragment="single">MNCVDNQDYYDLYAARLFKPPVVADSSTLMAKDTRTKRVTKPTKGKEKADEVKRRVLKTTKHTEAQIQPTQGPTPYTSAAPITDIYDPMMDVTPSLPIAQVPSSALSSIKRQRSTSTFPDTSLTYDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-06-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MW89</accession>
    <name>A0A1C7MW89_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_11235</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001811">
        <property type="protein sequence ID" value="OBZ80716.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MW89"/>
    <dbReference type="InParanoid" id="A0A1C7MW89"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ80716.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="83" mass="9506" checksum="ED09325B30C25C95" modified="2016-11-30" version="1" fragment="single">MLSKDCHKEAMSLCTKTLTFKTNAILCKDFGTADFEVGLWVAEDVDFRRLFTEERRKAVAFVNQGKYMKEDHYALVFCGTLAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MWE2</accession>
    <name>A0A1C7MWE2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_11175</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001742">
        <property type="protein sequence ID" value="OBZ80776.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MWE2"/>
    <dbReference type="InParanoid" id="A0A1C7MWE2"/>
    <dbReference type="OrthoDB" id="2288255at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="78"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="78"/>
            <end position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ80776.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="475" mass="55311" checksum="28009D8C2DAAC0BC" modified="2016-11-30" version="1">MNQQTWCLNNLATMSAKKFADEYKYSNPRVLSHQYLKIIKEITTGEEQKRLVKEYNAWKRSEDYEKYWNEKTKDLKDRNGTESKVEEKEENKESDKEDQKQEKKTSINSSQSKSNKKLTAAEKQRVLSNYAAIPENQFWYLSTGTCVNEKMKQLVELSVFEHPVHSLIFDPDDQIWLEYFSVDELDEIRTFKQKPLQELPTDLQNCLDIYDKQWKDGVELYQFASSQQFHPINDFEKNWVRESMMQVAKLFLSGTSRSMESMSEADQLHHLWSFVYHLYDISEIKALLGERSSGATSFARNQSRSLEVSNTRIRKNIGAKLDILYKWYSNEVGSCEVGKNDVESTDDKYINDGLMKLPKTLKDMLCVLQRENPEKVSSLKSIGLLIMGNKLELIVMDVPVGNHISRISRTMPFGFPSSIEQVNTNFLPLLELAWKGKQAMEELVAVLKNRKRKAVELRSTAITKSNMPFTLYREK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MWN1</accession>
    <name>A0A1C7MWN1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">RING finger protein B</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">A0J61_10739</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001357">
        <property type="protein sequence ID" value="OBZ81212.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MWN1"/>
    <dbReference type="STRING" id="101091.A0A1C7MWN1"/>
    <dbReference type="InParanoid" id="A0A1C7MWN1"/>
    <dbReference type="OrthoDB" id="432528at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.80">
        <property type="entry name" value="Kelch-type beta propeller"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015915">
        <property type="entry name" value="Kelch-typ_b-propeller"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46093:SF3">
        <property type="entry name" value="ACYL-COA-BINDING DOMAIN-CONTAINING PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46093">
        <property type="entry name" value="ACYL-COA-BINDING DOMAIN-CONTAINING PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24681">
        <property type="entry name" value="Kelch_KLHDC2_KLHL20_DRC7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117281">
        <property type="entry name" value="Kelch motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0880">Kelch repeat</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="96"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="149"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="413"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="540"/>
            <end position="638"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="541"/>
            <end position="557"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="577"/>
            <end position="590"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="628"/>
            <end position="638"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OBZ81212.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="638" mass="71547" checksum="1F5B91FAEA97D249" modified="2016-11-30" version="1" fragment="single">TGDNNEQIRNKAYLNQVAVLDTNTWQWSLPSIQGIPPSRRSYASGGLVGNNLVVAFGSGYNTYYNDINVLNLNTMSWLQSFDSSTGSGSSGLSGGAIAGISIACVVVLVIILFLLWKFQKYARWLVQRIHRDIWKPRTGEPLWAETTRIVCQIFLLFIFFIFLAFVIRQAINSPNVTQKIVKSVPEVQVPDVRFCFDGFPLYPSTDIRTPGVSCSTDTGYSCTQFVQPLNMSVFQPTFTDNLGAVSCVLFTAPKTFTLTSTSGSNNGSRLLFTMFGDQNAPQARVHVSVYPKAMDPNTVVYGLTPNEPNLMSTENILNWQTGERNDIQVNNIYTVEPFTYSALSYDLIDHQYLKDADWNYVGFLPISNSTPEVQTNFRSEAPNPNYRSGHIDLGVFAVFPGSFVTTIEREVKMYTLVNALGFVGGIFGLLIALQAWLFGYRPRSPWGVVHRWSVGNLKRSLLRGLHSKFKITESGVPLVHPVHHRFSVTNLNDLSYEDSEAQRINRVEERMQMLEMLFKAYYVDDEVFRSLDDANRVDTARNAQKSHGTSFNPNAHLNDSARFSPPPSFRNVVGTPKTEKVPDNDYHPVAKSEQPLVHPFTRQDTDASSASHIPLTHHQRPHAPPYQPSTTVQLSDED</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-06-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MWP8</accession>
    <name>A0A1C7MWP8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_10711</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001333">
        <property type="protein sequence ID" value="OBZ81240.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MWP8"/>
    <dbReference type="InParanoid" id="A0A1C7MWP8"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ81240.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="71" mass="8281" checksum="C41329071C7852DC" modified="2016-11-30" version="1" fragment="single">KSKRNTDKDNTITMHTRQRYLPSTDDSYISSKIISSSNNTADWIKEHMDNAGIDTSYTNLNQFEQLQVRKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MX95</accession>
    <name>A0A1C7MX95_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Large ribosomal subunit protein bL27m</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">MRP7</name>
        <name evidence="8" type="ORF">A0J61_10563</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the bacterial ribosomal protein bL27 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001237">
        <property type="protein sequence ID" value="OBZ81388.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MX95"/>
    <dbReference type="FunCoup" id="A0A1C7MX95">
        <property type="interactions" value="192"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7MX95"/>
    <dbReference type="InParanoid" id="A0A1C7MX95"/>
    <dbReference type="OrthoDB" id="1867012at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005762">
        <property type="term" value="C:mitochondrial large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.100:FF:000042">
        <property type="entry name" value="50S ribosomal protein L27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00539">
        <property type="entry name" value="Ribosomal_bL27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001684">
        <property type="entry name" value="Ribosomal_bL27"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018261">
        <property type="entry name" value="Ribosomal_bL27_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00062">
        <property type="entry name" value="L27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15893:SF0">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN BL27M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15893">
        <property type="entry name" value="RIBOSOMAL PROTEIN L27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01016">
        <property type="entry name" value="Ribosomal_L27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00063">
        <property type="entry name" value="RIBOSOMALL27"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110324">
        <property type="entry name" value="Ribosomal L27 protein-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00831">
        <property type="entry name" value="RIBOSOMAL_L27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 8" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="44"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010797"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00035267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OBZ81388.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="154" mass="16923" checksum="56BDBBD76CBB69DC" modified="2016-11-30" version="1">MSLLGRSFLQISSKLSNNVALSSQSRPMLMPLKNATDLGQVRWATKKSGGSSRNGRDSAGRRLGVKKFGGQQVVPGNIIVRQRGTKFHAGDNVGMGKDHTLFALEPGFVRFYSDPQHPKRRLVGIVYEQNATLPIPEGQPKPRRFDLVDLAALQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MXD2</accession>
    <name>A0A1C7MXD2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">ribonuclease T2</fullName>
            <ecNumber evidence="2">4.6.1.19</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">RNRH_0</name>
        <name evidence="7" type="ORF">A0J61_10482</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the RNase T2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.6.1.19" evidence="2"/>
    <dbReference type="EMBL" id="LUGH01001195">
        <property type="protein sequence ID" value="OBZ81470.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MXD2"/>
    <dbReference type="STRING" id="101091.A0A1C7MXD2"/>
    <dbReference type="InParanoid" id="A0A1C7MXD2"/>
    <dbReference type="OrthoDB" id="435754at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033897">
        <property type="term" value="F:ribonuclease T2 activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006401">
        <property type="term" value="P:RNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01061">
        <property type="entry name" value="RNase_T2_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.730.10">
        <property type="entry name" value="Ribonuclease T2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033697">
        <property type="entry name" value="Ribonuclease_T2_eukaryotic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001568">
        <property type="entry name" value="RNase_T2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036430">
        <property type="entry name" value="RNase_T2-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018188">
        <property type="entry name" value="RNase_T2_His_AS_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033130">
        <property type="entry name" value="RNase_T2_His_AS_2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11240">
        <property type="entry name" value="RIBONUCLEASE T2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11240:SF22">
        <property type="entry name" value="RIBONUCLEASE T2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00445">
        <property type="entry name" value="Ribonuclease_T2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55895">
        <property type="entry name" value="Ribonuclease Rh-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00530">
        <property type="entry name" value="RNASE_T2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00531">
        <property type="entry name" value="RNASE_T2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008889342" description="ribonuclease T2" evidence="6">
        <location>
            <begin position="20"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="active site" evidence="4">
        <location>
            <position position="66"/>
        </location>
    </feature>
    <feature type="active site" evidence="4">
        <location>
            <position position="125"/>
        </location>
    </feature>
    <feature type="active site" evidence="4">
        <location>
            <position position="129"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007469"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012571"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR633697-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU004328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OBZ81470.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="243" mass="26306" checksum="1D4DCF5302F8AD93" modified="2016-11-30" version="1">MKLSLLSFALLGLLGTAKADSDSCPLNVISCQASGADSCCSPTYGLLVLTQQWSPGYGPANQFTLHGLWPDTCSGAYGPSSGCDSSRSSSTIGTVIRNNDSALYNRMLTYWPSNQGDNNKFWSHEWTKHGTCVSTLKPTCYGDSYKKNQDVIDYFKQTMALRDEYNLYDALSASGITPGGSYNVEDMRDAIQEAFGATAKLDCISGAINEVGLYFYVKGTNTYIPTDTLALGNCKGSVKYPKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MXJ5</accession>
    <name>A0A1C7MXJ5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Large ribosomal subunit protein bL32m</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">mrpl32</name>
        <name evidence="8" type="ORF">A0J61_10471</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the bacterial ribosomal protein bL32 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001190">
        <property type="protein sequence ID" value="OBZ81481.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MXJ5"/>
    <dbReference type="FunCoup" id="A0A1C7MXJ5">
        <property type="interactions" value="184"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7MXJ5"/>
    <dbReference type="InParanoid" id="A0A1C7MXJ5"/>
    <dbReference type="OrthoDB" id="2014905at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005762">
        <property type="term" value="C:mitochondrial large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00340">
        <property type="entry name" value="Ribosomal_bL32"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051991">
        <property type="entry name" value="Mitoribosomal_protein_bL32"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002677">
        <property type="entry name" value="Ribosomal_bL32"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011332">
        <property type="entry name" value="Ribosomal_zn-bd"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01031">
        <property type="entry name" value="rpmF_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21026">
        <property type="entry name" value="39S RIBOSOMAL PROTEIN L32, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21026:SF2">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN BL32M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01783">
        <property type="entry name" value="Ribosomal_L32p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57829">
        <property type="entry name" value="Zn-binding ribosomal proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4 8" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="3" id="KW-0809">Transit peptide</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00039935"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OBZ81481.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="111" mass="12621" checksum="ED824F6F4181B4AE" modified="2016-11-30" version="1">MSMLRFVSIRPILQQQAMKAPTLRFGTLTNRWNESISHSTFQIPTWLESILWAAPKKKTSHSKKRMRASNKGLKQKENVTSCPACGSNKLLHHLCGHCYGDIKKKAKLSVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MYA7</accession>
    <name>A0A1C7MYA7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">60S ribosomal protein L44 Q</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">RIM-C</name>
        <name evidence="6" type="ORF">A0J61_10129</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the eukaryotic ribosomal protein eL42 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001045">
        <property type="protein sequence ID" value="OBZ81820.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MYA7"/>
    <dbReference type="STRING" id="101091.A0A1C7MYA7"/>
    <dbReference type="InParanoid" id="A0A1C7MYA7"/>
    <dbReference type="OrthoDB" id="2967263at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.450.80:FF:000001">
        <property type="entry name" value="60S ribosomal protein L44"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.450.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000552">
        <property type="entry name" value="Ribosomal_eL44"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053708">
        <property type="entry name" value="Ribosomal_LSU_eL42"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011332">
        <property type="entry name" value="Ribosomal_zn-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10369">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L36A/L44"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00935">
        <property type="entry name" value="Ribosomal_L44"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57829">
        <property type="entry name" value="Zn-binding ribosomal proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01172">
        <property type="entry name" value="RIBOSOMAL_L44E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 6" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009364"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000666"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OBZ81820.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="76" mass="8563" checksum="E3DC5E7F978ED06B" modified="2016-11-30" version="1" fragment="single">GKASLFAQGKRRYDRKQSGYGGQTKPVFHKKAKTTKKVVLRLECTACKYKMQLALKRCKHFELGGDKKTKGAALVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MYF8</accession>
    <name>A0A1C7MYF8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Proteasome subunit alpha type</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">Psma6</name>
        <name evidence="7" type="ORF">A0J61_10108</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="5">The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="5">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 5">Belongs to the peptidase T1A family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001036">
        <property type="protein sequence ID" value="OBZ81842.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MYF8"/>
    <dbReference type="FunCoup" id="A0A1C7MYF8">
        <property type="interactions" value="545"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7MYF8"/>
    <dbReference type="InParanoid" id="A0A1C7MYF8"/>
    <dbReference type="OrthoDB" id="431557at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019773">
        <property type="term" value="C:proteasome core complex, alpha-subunit complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010499">
        <property type="term" value="P:proteasomal ubiquitin-independent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043161">
        <property type="term" value="P:proteasome-mediated ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd03754">
        <property type="entry name" value="proteasome_alpha_type_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.20.10:FF:000036">
        <property type="entry name" value="Proteasome subunit alpha type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.10">
        <property type="entry name" value="Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050115">
        <property type="entry name" value="Proteasome_alpha"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023332">
        <property type="entry name" value="Proteasome_alpha-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000426">
        <property type="entry name" value="Proteasome_asu_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001353">
        <property type="entry name" value="Proteasome_sua/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034642">
        <property type="entry name" value="Proteasome_subunit_alpha6"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003075">
        <property type="entry name" value="PRK03996.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11599">
        <property type="entry name" value="PROTEASOME SUBUNIT ALPHA/BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00227">
        <property type="entry name" value="Proteasome"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10584">
        <property type="entry name" value="Proteasome_A_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00948">
        <property type="entry name" value="Proteasome_A_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="N-terminal nucleophile aminohydrolases (Ntn hydrolases)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00388">
        <property type="entry name" value="PROTEASOME_ALPHA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51475">
        <property type="entry name" value="PROTEASOME_ALPHA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="2 4 5" id="KW-0647">Proteasome</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Proteasome alpha-type subunits" evidence="6">
        <location>
            <begin position="9"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00808"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU000551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS00388"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OBZ81842.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="246" mass="27435" checksum="8CD7A8E6C025F00E" modified="2016-11-30" version="1">MSRGSGAGYDRHITIFSPEGRLYQVEYAFKAISNSGITSIGVRGRDGCVVVTQRKVPDKLLDPSTITHVFKLTPKIGCVMTGMIADARSQVTRARQEAAEFRYKYGYEIPTDMLAKRVANINQVYTQQAAMRPYGVSMILVGYDDELGPQLYKCDPAGYYVGYKATSAGAKQQEALNHLEKKLKKNPELNMEDAIELAITTLSTVLAVDFKATEIEVGIVHKEDTDFRTLSTEEIEDHLQRIVEKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MYI9</accession>
    <name>A0A1C7MYI9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 14">Saccharopine dehydrogenase [NAD(+), L-lysine-forming]</fullName>
            <shortName evidence="14">SDH</shortName>
            <ecNumber evidence="5 14">1.5.1.7</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12 14">Lysine--2-oxoglutarate reductase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="20" type="primary">lys3</name>
        <name evidence="20" type="ORF">A0J61_09977</name>
    </gene>
    <organism evidence="20 21">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="20 21" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="20 21">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the NAD(+)-dependent cleavage of saccharopine to L-lysine and 2-oxoglutarate, the final step in the alpha-aminoadipate (AAA) pathway for lysin biosynthesis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13 14">
            <text>L-saccharopine + NAD(+) + H2O = L-lysine + 2-oxoglutarate + NADH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:12440"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:32551"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:57951"/>
            <dbReference type="EC" id="1.5.1.7"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 14">Amino-acid biosynthesis; L-lysine biosynthesis via AAA pathway; L-lysine from L-alpha-aminoadipate (fungal route): step 3/3.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Monomer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 14">Belongs to the AlaDH/PNT family.</text>
    </comment>
    <comment type="caution">
        <text evidence="20">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.5.1.7" evidence="5 14"/>
    <dbReference type="EMBL" id="LUGH01000989">
        <property type="protein sequence ID" value="OBZ81975.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MYI9"/>
    <dbReference type="FunCoup" id="A0A1C7MYI9">
        <property type="interactions" value="377"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7MYI9"/>
    <dbReference type="InParanoid" id="A0A1C7MYI9"/>
    <dbReference type="OrthoDB" id="265306at2759"/>
    <dbReference type="UniPathway" id="UPA00033">
        <property type="reaction ID" value="UER00034"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004754">
        <property type="term" value="F:saccharopine dehydrogenase (NAD+, L-lysine-forming) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019878">
        <property type="term" value="P:lysine biosynthetic process via aminoadipic acid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016558">
        <property type="term" value="P:protein import into peroxisome matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd12188">
        <property type="entry name" value="SDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000217">
        <property type="entry name" value="Saccharopine dehydrogenase [NAD(+), L-lysine-forming]"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000627">
        <property type="entry name" value="Saccharopine dehydrogenase [NAD(+), L-lysine-forming]"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051168">
        <property type="entry name" value="AASS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007886">
        <property type="entry name" value="AlaDH/PNT_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007698">
        <property type="entry name" value="AlaDH/PNT_NAD(H)-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027281">
        <property type="entry name" value="Lys1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11133">
        <property type="entry name" value="SACCHAROPINE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11133:SF23">
        <property type="entry name" value="SACCHAROPINE DEHYDROGENASE [NAD(+), L-LYSINE-FORMING]"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05222">
        <property type="entry name" value="AlaDh_PNT_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF018250">
        <property type="entry name" value="Saccharopine_DH_Lys"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01002">
        <property type="entry name" value="AlaDh_PNT_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01003">
        <property type="entry name" value="AlaDh_PNT_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52283">
        <property type="entry name" value="Formate/glycerate dehydrogenase catalytic domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 14" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="11" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="10 14" id="KW-0457">Lysine biosynthesis</keyword>
    <keyword evidence="9 14 16" id="KW-0520">NAD</keyword>
    <keyword evidence="8 14" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Alanine dehydrogenase/pyridine nucleotide transhydrogenase N-terminal" evidence="19">
        <location>
            <begin position="12"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="domain" description="Alanine dehydrogenase/pyridine nucleotide transhydrogenase NAD(H)-binding" evidence="18">
        <location>
            <begin position="191"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="15">
        <location>
            <position position="83"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="15">
        <location>
            <position position="102"/>
        </location>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="136"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <begin position="209"/>
            <end position="210"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="233"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="237"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="257"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="283"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <begin position="323"/>
            <end position="326"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="disulfide bond" evidence="17">
        <location>
            <begin position="211"/>
            <end position="255"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005689"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00021221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023154"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00033228"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00047860"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PIRNR" id="PIRNR018250"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PIRSR" id="PIRSR018250-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PIRSR" id="PIRSR018250-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="PIRSR" id="PIRSR018250-4"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="SMART" id="SM01002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="SMART" id="SM01003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="OBZ81975.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="374" mass="41612" checksum="E4BD8A2187D060E0" modified="2016-11-30" version="1">MSTTTGNGPHLWLRAETKPMEHRAALTPATAKTLLDAGFRITVERSEQRIFDDEEYAKVGCPLVEKLSWKTDAPADAYIVGLKELPENDDSPLNHTHIFFAHCFKNQGGWKELLHRFDAGNGTILDLEFLNDANGRRVAAFGYMAGFAGSAVGVDVWCHQKFGTNEKYGALTPYPNEEALISYTKDRLAKAIALNNNEYPKVMVMGALGRCGTGACDFARKVGIPEENIIKWDINETKKGGPFPEILQSDIFVNCIYLNQKIPPFITQEMINGDRKLSIICDVSCDTTNPNNPIPVYSINTTFDKPTVPVETTNPYPLEVCSIDHLPTLLPRESSDMFSHDLLPTMLALKDRSNSPVWIGAENLYKEKLQASRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MZ73</accession>
    <name>A0A1C7MZ73_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein C29B5.04c</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_09868</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000959">
        <property type="protein sequence ID" value="OBZ82082.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MZ73"/>
    <dbReference type="STRING" id="101091.A0A1C7MZ73"/>
    <dbReference type="InParanoid" id="A0A1C7MZ73"/>
    <dbReference type="OrthoDB" id="2117591at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008195">
        <property type="term" value="F:phosphatidate phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019236">
        <property type="entry name" value="APP1_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052935">
        <property type="entry name" value="Mg2+_PAP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28208">
        <property type="entry name" value="PHOSPHATIDATE PHOSPHATASE APP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28208:SF3">
        <property type="entry name" value="PHOSPHATIDATE PHOSPHATASE APP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09949">
        <property type="entry name" value="APP1_cat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Phosphatidate phosphatase APP1 catalytic" evidence="2">
        <location>
            <begin position="227"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="39"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="39"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="56"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF09949"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ82082.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="491" mass="55385" checksum="D77F8862A8BF98EA" modified="2016-11-30" version="1">MNNLPISSTKLRKRDQLLSFVQSKSHVLKQEFNRYASTSVPNLTSSSSSTRSTSSLNEQGHRTTVQRSETQEIDDILQDNNPEISQPQCILFPTYASPYQDLGYKVILSGWAFTKPTSSRLDRWLLAAGRSYGGLERDSVEDHHFSNLLNHFRSQSMRMTEIALALPSILKERMAEHINTGPTGRFQQELYLDPHVKGPCTVEASFLTDSAKVIASTSIDVIDHLGISIISDIDDTIKITGVLDGKDTILQNTFFRKARQVPHMSEVYQNWASIGAHIHYVSNSPWQVFPALSEFMTQQHFPQGSVHLRNVGTGDLLRNKPGKHKLEVISAILRDFPHRKFILVGDSGEMDPEIYQQIYELFPDQVIKIFIHDVSSERAINADRLARDRPDSYYSSVRKFLSRESIIRKGSSSQLVMDAMAQTEIPEEQQDMGDPQIPLLTKLEQFEARMKRVSGKLPDGLFTVFTLATQLILDPVVTEGFLMYSSSSSSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MZ94</accession>
    <name>A0A1C7MZ94_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Mitochondrial import inner membrane translocase subunit TIM17</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">TIM17</name>
        <name evidence="11" type="ORF">A0J61_09857</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the Tim17/Tim22/Tim23 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000956">
        <property type="protein sequence ID" value="OBZ82091.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MZ94"/>
    <dbReference type="FunCoup" id="A0A1C7MZ94">
        <property type="interactions" value="151"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7MZ94"/>
    <dbReference type="InParanoid" id="A0A1C7MZ94"/>
    <dbReference type="OrthoDB" id="2261329at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005744">
        <property type="term" value="C:TIM23 mitochondrial import inner membrane translocase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008320">
        <property type="term" value="F:protein transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030150">
        <property type="term" value="P:protein import into mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10485:SF0">
        <property type="entry name" value="AT05822P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10485">
        <property type="entry name" value="MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM-17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02466">
        <property type="entry name" value="Tim17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0811">Translocation</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="non-terminal residue" evidence="11">
        <location>
            <position position="149"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008444"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="OBZ82091.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="149" mass="15208" checksum="FEE68A3B4AA39DD9" modified="2016-11-30" version="1" fragment="single">MGRSAQDHSRDPCPWVILNDLGGAFVMGAVGGGIWHSVKGAKNSPRGERLTGAVSAMKARAPVLGGNFAVWGGLFSTFDCALKGIRQKEDPWNSIISGGVTGGVLAARGGVKAAAVSAVVGGSLLALIEGVGIAITRMTADQHKPMMPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MZB1</accession>
    <name>A0A1C7MZB1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Endonuclease/exonuclease/phosphatase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_10204</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001072">
        <property type="protein sequence ID" value="OBZ81746.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MZB1"/>
    <dbReference type="InParanoid" id="A0A1C7MZB1"/>
    <dbReference type="OrthoDB" id="2282763at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.10.10">
        <property type="entry name" value="Endonuclease/exonuclease/phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036691">
        <property type="entry name" value="Endo/exonu/phosph_ase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005135">
        <property type="entry name" value="Endo/exonuclease/phosphatase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03372">
        <property type="entry name" value="Exo_endo_phos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56219">
        <property type="entry name" value="DNase I-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Endonuclease/exonuclease/phosphatase" evidence="1">
        <location>
            <begin position="11"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="191"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03372"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ81746.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="191" mass="21481" checksum="CA469E4D4927259A" modified="2016-11-30" version="1" fragment="single">MEVPFFSPTHAADIPSFILGDLNSTLKDPSFQNHVFVEPLLEWLNAHYTNCFPDALPTYTSAANHNTRKTIDYTFVDKSWMISVTSPPTAPPVPFVASIATKRHRGWESVKLLLQNAAKSYSRHSKARSQHILSRLQLERNDLLASVSSAVSFDAAHLSRLQQRDTAIEALVEKETAQYSLRTATRWNDQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MZT6</accession>
    <name>A0A1C7MZT6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Cytochrome b-c1 complex subunit Rieske, mitochondrial</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">rip1_0</name>
        <name evidence="2" type="ORF">A0J61_09582</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000884">
        <property type="protein sequence ID" value="OBZ82367.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MZT6"/>
    <dbReference type="SMR" id="A0A1C7MZT6"/>
    <dbReference type="STRING" id="101091.A0A1C7MZT6"/>
    <dbReference type="InParanoid" id="A0A1C7MZT6"/>
    <dbReference type="OrthoDB" id="1637982at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008121">
        <property type="term" value="F:quinol-cytochrome-c reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.102.10.10">
        <property type="entry name" value="Rieske [2Fe-2S] iron-sulphur domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.270">
        <property type="entry name" value="Ubiquinol cytochrome reductase, transmembrane domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037008">
        <property type="entry name" value="bc1_Rieske_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036922">
        <property type="entry name" value="Rieske_2Fe-2S_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014349">
        <property type="entry name" value="Rieske_Fe-S_prot"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004192">
        <property type="entry name" value="Rieske_TM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10134">
        <property type="entry name" value="CYTOCHROME B-C1 COMPLEX SUBUNIT RIESKE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02921">
        <property type="entry name" value="UCR_TM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50022">
        <property type="entry name" value="ISP domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81502">
        <property type="entry name" value="ISP transmembrane anchor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cytochrome b-c1 complex subunit Rieske transmembrane" evidence="1">
        <location>
            <begin position="86"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="212"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02921"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ82367.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="212" mass="23282" checksum="65190536BDCF66BE" modified="2016-11-30" version="1" fragment="single">MASLSRTFASAISNRSYTNVPASANALKRIFHYSSTSEDEHHETTNSQSLFNAATKQRSTGGLVQKSSVNVSPINQFQLRRNHTTSVPDFSKYKKEKSSGEASRNFAYMMVGTTGLISAAGAQATVSDFLANMSASADVLALAKAEVDMASIPEGKNVTIKWRGKPVFIRHRTQSEIEEANQVNITELRDPQQDAERVKDPKWLVMLGVCTH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N030</accession>
    <name>A0A1C7N030_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_09927</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000973">
        <property type="protein sequence ID" value="OBZ82026.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N030"/>
    <dbReference type="InParanoid" id="A0A1C7N030"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12937">
        <property type="entry name" value="F-box-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="1">
        <location>
            <begin position="8"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12937"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ82026.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="559" mass="63907" checksum="FECD4D5E30071390" modified="2016-11-30" version="1">MPTRQLSNEIHLGILTYLTRKDQIQYSLVCRNWREAAKHLLFKTICLNDDQQIASFVHLLATAPSLRDLVKILVLRGRRCLTNETVCASLIHMTPCLKTLITDFASMLLYQIASQEVKFGHWCFLDYLEYKHFEYDHVSTIGMDDGYHALLASLQDRLSTVTLSIQSHPQSPLEPICFHFPLLINRQTCFGASKHLICISNSMAAIRSLDDALKLCPHATKLTLDLDHLDSYEDQMIPIVPNTTIEHLSINLSYGTPAIFDYMNSKFTGIKQLTLTIHRLDISPKNTPYSDATLESTILQIFQCAQTTDVFDIALEEMGNYLKLTSFFLHPWEGAMEIILDRNMIQLKHDKSKSKHSYLCIKPDAGQTDFLLGMPTAYLNRLNTLDLAKLHPSYGRPLAYCTHLQALYLSYDGGLDAYSGPTLPITHLTLRRMGDSGYFQTQFTRQTPNLRHVCIETTGNDDRIDMPTCSFDSIRIRVRHNQLSRQFSIHLRYSGQSTFYQVTNNQTVSTYRSLVGEVFVIQCRETKYVEIQWDDFLFSLELPSPLSLKTPKINPLDPT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N0D0</accession>
    <name>A0A1C7N0D0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">MULE transposase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_11148</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001715">
        <property type="protein sequence ID" value="OBZ80804.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="InParanoid" id="A0A1C7N0D0"/>
    <dbReference type="OrthoDB" id="2422867at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031052">
        <property type="entry name" value="FHY3/FAR1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018289">
        <property type="entry name" value="MULE_transposase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31669:SF251">
        <property type="entry name" value="PROTEIN FAR1-RELATED SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31669">
        <property type="entry name" value="PROTEIN FAR1-RELATED SEQUENCE 10-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10551">
        <property type="entry name" value="MULE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MULE transposase" evidence="1">
        <location>
            <begin position="48"/>
            <end position="153"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF10551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ80804.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="263" mass="30090" checksum="3C4D55F77DC32981" modified="2016-11-30" version="1">MMYEYVNRLQSKGYEVFCTLDSDRRVNAVFFSSKSSIERARLXPENLVIGATYKINAHRLAFINIVGTSSVEGSKPSTLVTLEVASAFISEEGFNQYQWVLRCLKEAIWSQSAEESHPGPLTITTDNEQALKNAIADVFPSTQHILCYVHMQKRVEIKLMECISEKDKDRRDIIRQEIQKRFQAIVLKAITRKEINVAVLDLKNLFLDEPDIFPESVKQNMEVQVDGTLLFISYVSEEGKKKAVIFIESKMEEAEKMDSFSYA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N135</accession>
    <name>A0A1C7N135_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">60S ribosomal protein L13</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">rpl13_1</name>
        <name evidence="7" type="synonym">rpl13_0</name>
        <name evidence="7" type="ORF">A0J61_07849</name>
        <name evidence="6" type="ORF">A0J61_09549</name>
    </gene>
    <organism evidence="6 8">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 8" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the eukaryotic ribosomal protein eL13 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000876">
        <property type="protein sequence ID" value="OBZ82396.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="LUGH01000556">
        <property type="protein sequence ID" value="OBZ84101.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N135"/>
    <dbReference type="FunCoup" id="A0A1C7N135">
        <property type="interactions" value="516"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N135"/>
    <dbReference type="InParanoid" id="A0A1C7N135"/>
    <dbReference type="OrthoDB" id="10264538at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022625">
        <property type="term" value="C:cytosolic large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.5.110:FF:000003">
        <property type="entry name" value="60S ribosomal protein L13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00499">
        <property type="entry name" value="Ribosomal_eL13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001380">
        <property type="entry name" value="Ribosomal_eL13"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018256">
        <property type="entry name" value="Ribosomal_eL13_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11722">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11722:SF0">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN EL13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01294">
        <property type="entry name" value="Ribosomal_L13e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01104">
        <property type="entry name" value="RIBOSOMAL_L13E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 6" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="190"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="193"/>
            <end position="211"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000572"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OBZ82396.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OBZ84101.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="211" mass="24250" checksum="EE3C4953AF891572" modified="2016-11-30" version="1">MVLKHNNQLPNQHFRKQWDRRVKTWFDQAGRKQSRRIARAQKAGRIAPRPLDGLLRPAVRCPTVRYNMKLRAGRGFTLEELKEAGIRRKEARTIGIAVDFRRRNRSNESLELNVQRLKAYKAKLIVFPRKATSPKKGDSEPTEVATAVQLRTPLFPVEQVAAAPEARAITAEEKNVNAYMKLRYARSAARTLGAREKRARDKAEEEANKKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N136</accession>
    <name>A0A1C7N136_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">F-box/WD repeat-containing protein 7</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">FBXW7</name>
        <name evidence="2" type="ORF">A0J61_09161</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000786">
        <property type="protein sequence ID" value="OBZ82793.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N136"/>
    <dbReference type="STRING" id="101091.A0A1C7N136"/>
    <dbReference type="InParanoid" id="A0A1C7N136"/>
    <dbReference type="OrthoDB" id="3219396at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25499">
        <property type="entry name" value="Beta-prop_pof12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12937">
        <property type="entry name" value="F-box-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00256">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="1">
        <location>
            <begin position="24"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ82793.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="442" mass="50660" checksum="35E4D9F9865EE76D" modified="2016-11-30" version="1">MTLSIKKRIKRLNKSTCESDKRIDFTRSLFSKELVLKVFGFLSSSDLVQCAAVNYRWFQIANDELLWKPLFIKTFSTHEKPTAIRYGGSWKTKYRIHHNWLLGNYNINDVVQRPDDSTPHHIQFLHDVLFISQRHTIDIWQYRKERSSRISQLNASTSQVCYLKLVDHQPTVRFLIASYADGQLCIWQINGLSSADLAITHQLSHMAHPAVSLDMHYPLLAIYTVQKTLVVYRLDGPELVEIACLQSPMDWSPVIMDIQPMRSPGRWQVVLCFGSSSSHSGPSSVGIQEMIFSDSRLLSSRQGMYTYPMSLSCASLDQITSMVYAAPYLITAHPNNTMKQYRITNRGRHLDISFQQTLYGHTCRVDALAIAKQKLISGDRSGIKIWDLARQQQVMTLNIYPDQSSMNELPESSIRTLGFDEDKIVAVVNDNNNAFVRLWSFN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N1F2</accession>
    <name>A0A1C7N1F2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Methionine adenosyltransferase 2 subunit beta</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">mat2b</name>
        <name evidence="2" type="ORF">A0J61_09107</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000775">
        <property type="protein sequence ID" value="OBZ82841.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N1F2"/>
    <dbReference type="FunCoup" id="A0A1C7N1F2">
        <property type="interactions" value="21"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N1F2"/>
    <dbReference type="InParanoid" id="A0A1C7N1F2"/>
    <dbReference type="OrthoDB" id="6235964at2759"/>
    <dbReference type="UniPathway" id="UPA00315">
        <property type="reaction ID" value="UER00080"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048269">
        <property type="term" value="C:methionine adenosyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048270">
        <property type="term" value="F:methionine adenosyltransferase regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006556">
        <property type="term" value="P:S-adenosylmethionine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd05254">
        <property type="entry name" value="dTDP_HR_like_SDR_e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000357">
        <property type="entry name" value="Methionine adenosyltransferase 2 subunit beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005913">
        <property type="entry name" value="dTDP_dehydrorham_reduct"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029903">
        <property type="entry name" value="RmlD-like-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10491">
        <property type="entry name" value="DTDP-4-DEHYDRORHAMNOSE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10491:SF4">
        <property type="entry name" value="METHIONINE ADENOSYLTRANSFERASE 2 SUBUNIT BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04321">
        <property type="entry name" value="RmlD_sub_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="RmlD-like substrate binding" evidence="1">
        <location>
            <begin position="1"/>
            <end position="278"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF04321"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ82841.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="300" mass="33325" checksum="722978E5E857C44D" modified="2016-11-30" version="1">MKAVVTGASGLLGRPVVKQFENAGWEVIGTAYSRAKNNLLKLDLTDGDAVEQFLNEHKPDVVVHCAAERRPDVADQDRDGALRLNVETPKKLGKLCKEKHIMLIYISTDYVFDGTSPPYEVDDKPNPLQFYGETKLAGEEAIKSVYPDATILRVPILYGHTEYNSESAINILIDVVMNSDKPSSVDNVAVRYPTNVEDVGRVLKDLAVAKLQNGKDIKGIYHFTARECLTKYQVCEIFADVLNVSINHLTPQNTVDKAASVSRPENSHLSVKRLEEDGIDTGFVKFTEWCSNNLSSKNKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N255</accession>
    <name>A0A1C7N255_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Exopolygalacturonase rpg16</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">rpg16_4</name>
        <name evidence="13" type="ORF">A0J61_08829</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the glycosyl hydrolase 28 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000718">
        <property type="protein sequence ID" value="OBZ83117.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N255"/>
    <dbReference type="STRING" id="101091.A0A1C7N255"/>
    <dbReference type="InParanoid" id="A0A1C7N255"/>
    <dbReference type="OrthoDB" id="187139at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004650">
        <property type="term" value="F:polygalacturonase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046576">
        <property type="term" value="F:rhamnogalacturonan alpha-L-rhamnopyranosyl-(1-&gt;4)-alpha-D-galactopyranosyluronide lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045490">
        <property type="term" value="P:pectin catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.20.10">
        <property type="entry name" value="Single-stranded right-handed beta-helix, Pectin lyase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000743">
        <property type="entry name" value="Glyco_hydro_28"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006626">
        <property type="entry name" value="PbH1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012334">
        <property type="entry name" value="Pectin_lyas_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011050">
        <property type="entry name" value="Pectin_lyase_fold/virulence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31736">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31736:SF19">
        <property type="entry name" value="PECTIN LYASE SUPERFAMILY PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00295">
        <property type="entry name" value="Glyco_hydro_28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00710">
        <property type="entry name" value="PbH1"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51126">
        <property type="entry name" value="Pectin lyase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="7" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="8" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="9 11" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="6 11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0964">Secreted</keyword>
    <keyword evidence="4 12" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="12">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008889433" evidence="12">
        <location>
            <begin position="24"/>
            <end position="381"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008834"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU361169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="OBZ83117.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="381" mass="40471" checksum="92690E26CE1A1290" modified="2016-11-30" version="1">MVYVPSLTSAFALLTVLATSAQAATCTVSNKGNVANNIVSAFNNCKNGGTVVFTKGVTYNLNDLVQVQGLKNVNVHFYGTLNLPDYNTKYNGKSAYFIIKGDKINFDGGNTGVFNGNGQKWWDAKNRKAPTVLRITATGGSNFANFKIVQAPRAHIGITSSDGVTLNKITINTVSKSSNDAHNTDAVDISNSKNVNWFNSVVRNGDDCMAINGNTSNVNVDNVQCTGSHGFSVGSLGKGGETAVVSNIKVANSKCTNCQNGLRIKTWPGGKGSVSNVQFSNVQLNNSDNPILITTHYCDNNQQSFCKGNDNASLSIKNVQIKNISGSVSSKGRPAISINCSKNTPCSNFSLSNINISKSSKTKKNECINLSGSNSIAYCKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N328</accession>
    <name>A0A1C7N328_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_08542</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000668">
        <property type="protein sequence ID" value="OBZ83408.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="InParanoid" id="A0A1C7N328"/>
    <dbReference type="OrthoDB" id="2253871at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12937">
        <property type="entry name" value="F-box-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="1">
        <location>
            <begin position="1"/>
            <end position="44"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ83408.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="575" mass="66893" checksum="55E3DAF7C1447DE8" modified="2016-11-30" version="1">MLQNQPLEIILGIFSFLDLNTLIQCQLVSRKWSQPAQAQIYNKISFYGAEKGRLLLRTLKSSSFIGSLVRQLEFCSVHIREIEDYRQWIQHTPNLRLFYDFGLRDAHYELILQLINQGYWEKLDSLHYPVSFCRTNTDKQPVTILEEYYYYAVCSAKKDRLKTIAFDATTFSQPHGEIHCFRFPDCITRQTXFNKVEHLTCTSNTSMSLKDLEDILQLCPAMNILTLNFVSLVIHANDLHAIKPNTLVNNLRLEVKEANENHFRYVFKKFPNVKRLCLIMNYHVSDATIYLNRLSFEVINLLVVYATQADTLELQVNGISNTMDLFDNFKTATFKTGRMALSLKTSSASSSLLFIPNFKVEFQKESSSTSSLCLEHGQFPLDFGKXNATFLSTLNRFRYIGPIVPIDPTLETCKQILKFCKELYYLEIERYDFDEFVLPTSIQSYKGIDLNEYICYGGALKTLSRSFPRLTELHFAATDIEQKDGFYDPELPDLELDMLKCNDSMYPVPLLLRLREDDCNDTYFHLKNYQLLEITKEEFNRQVLDPKALKFDVVSQFLVALEMEFEGIFCSHKLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N347</accession>
    <name>A0A1C7N347_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Programmed cell death protein 6</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">Pdcd6_1</name>
        <name evidence="8" type="ORF">A0J61_08426</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000647">
        <property type="protein sequence ID" value="OBZ83522.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N347"/>
    <dbReference type="STRING" id="101091.A0A1C7N347"/>
    <dbReference type="InParanoid" id="A0A1C7N347"/>
    <dbReference type="OrthoDB" id="186625at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048306">
        <property type="term" value="F:calcium-dependent protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051426">
        <property type="entry name" value="Peflin/Sorcin_CaBP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46212:SF3">
        <property type="entry name" value="GH27120P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46212">
        <property type="entry name" value="PEFLIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13202">
        <property type="entry name" value="EF-hand_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13499">
        <property type="entry name" value="EF-hand_7"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00054">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0106">Calcium</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="EF-hand" evidence="7">
        <location>
            <begin position="71"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="7">
        <location>
            <begin position="108"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="7">
        <location>
            <begin position="138"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="12"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="6">
        <location>
            <begin position="45"/>
            <end position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OBZ83522.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="244" mass="27798" checksum="58A1EB6B848F5B89" modified="2016-11-30" version="1">MSYNQGYGGYNPQGYQQGGYQQQGYGAPPPQSPYNSYRPQAQGGYPPPQQGGYPPPQQGYALQRPHGPPPGSDPQLWSWFTAVDTDNSGQLSVDELQRALVNGDWSPFNIETVRTMVNMFDKDNSGTIDFNEFAGLWKYIEDWKRCFQTFDADNSGNIDVVEMRNALKTFGYNLSDQFIRVLVQKFDKYGHVEGKGNITFDNFVQACVTVKTLTDSFRQFDTDNDGWIQINYEQFLELVIRQRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N419</accession>
    <name>A0A1C7N419_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Rho GTPase-activating protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">ARHGAP1</name>
        <name evidence="2" type="ORF">A0J61_08544</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000668">
        <property type="protein sequence ID" value="OBZ83406.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N419"/>
    <dbReference type="FunCoup" id="A0A1C7N419">
        <property type="interactions" value="428"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N419"/>
    <dbReference type="InParanoid" id="A0A1C7N419"/>
    <dbReference type="OrthoDB" id="19923at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007264">
        <property type="term" value="P:small GTPase-mediated signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.525.10">
        <property type="entry name" value="CRAL-TRIO lipid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.555.10">
        <property type="entry name" value="Rho GTPase activation protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001251">
        <property type="entry name" value="CRAL-TRIO_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036865">
        <property type="entry name" value="CRAL-TRIO_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008936">
        <property type="entry name" value="Rho_GTPase_activation_prot"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000198">
        <property type="entry name" value="RhoGAP_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45808">
        <property type="entry name" value="RHO GTPASE-ACTIVATING PROTEIN 68F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45808:SF2">
        <property type="entry name" value="RHO GTPASE-ACTIVATING PROTEIN 68F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13716">
        <property type="entry name" value="CRAL_TRIO_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00620">
        <property type="entry name" value="RhoGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00324">
        <property type="entry name" value="RhoGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48350">
        <property type="entry name" value="GTPase activation domain, GAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50238">
        <property type="entry name" value="RHOGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rho-GAP" evidence="1">
        <location>
            <begin position="108"/>
            <end position="337"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50238"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ83406.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="338" mass="38543" checksum="D4A5F185CB289042" modified="2016-11-30" version="1">MSKAFALSSSSPEYKGIAGLNIIYEAGLDRESRPVLILCADNLPNPDIYDYDLILSFILARLDEFVENDYVLVFFSSPARYRPGWLWLLRAYRSLDRKLIFDLANKIVSLEELKQYVELAAQFIPQRVVDYDQQLPTTYSSYFSMLQQRQLSASSPSLAFGLDKEGIFRKSPASDELQAVKNAFNKGEAVNLNQYDIDVSAALFKVFIRELPTPLISLKLSENMGALPDASICTKGTIDKIRNKLLEQYKDTPNYLYLLNYVCKFLKEVSDNSNKNRMNTHNLSVVFTPNMIRADESLKNVHETEQSALADAAIYLKQMEQGMQLVRLLIAKHEDIFQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N4V9</accession>
    <name>A0A1C7N4V9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_09590</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000885">
        <property type="protein sequence ID" value="OBZ82364.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N4V9"/>
    <dbReference type="STRING" id="101091.A0A1C7N4V9"/>
    <dbReference type="InParanoid" id="A0A1C7N4V9"/>
    <dbReference type="OrthoDB" id="5430106at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031931">
        <property type="term" value="C:TORC1 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031929">
        <property type="term" value="P:TOR signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018857">
        <property type="entry name" value="TORC1_cplx_su_TCO89"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10452">
        <property type="entry name" value="TCO89"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="25"/>
            <end position="36"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ82364.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="285" mass="32341" checksum="F206D380798AFD4F" modified="2016-11-30" version="1">MVGEEEEDVTQKKPSRSTTPTATKRPVRHHVKRRSSGKVVHVTKLTPMAKMHHHTDSEADPSDETHRPAIKRSQSQRSFHPLKDTKHKTPAIPSSLTCKAMADPIQQPLNALANNLSVPKLDSNHCLMPKLPPEPAIKPTTQKHLLRSQFISPDDPMRPMSRTQQKLMLQKQQCSVQDETSPFHPRNIQKLNKELDAISRQLRCIKRYQDPMRASLARCIEPHLASGEHRSIAHRYHRLKEVALSRQQQASHTAAYPPSKEEPHGFSWSAAAFLDKLFHPTLSST</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N5G9</accession>
    <name>A0A1C7N5G9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Hsp90 chaperone protein kinase-targeting subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">cdc37</name>
        <name evidence="11" type="ORF">A0J61_09358</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the CDC37 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000831">
        <property type="protein sequence ID" value="OBZ82594.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N5G9"/>
    <dbReference type="FunCoup" id="A0A1C7N5G9">
        <property type="interactions" value="532"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N5G9"/>
    <dbReference type="InParanoid" id="A0A1C7N5G9"/>
    <dbReference type="OrthoDB" id="440202at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031072">
        <property type="term" value="F:heat shock protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019901">
        <property type="term" value="F:protein kinase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051087">
        <property type="term" value="F:protein-folding chaperone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050821">
        <property type="term" value="P:protein stabilization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.610">
        <property type="entry name" value="Cdc37, Hsp90 binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004918">
        <property type="entry name" value="Cdc37"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013873">
        <property type="entry name" value="Cdc37_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013874">
        <property type="entry name" value="Cdc37_Hsp90-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038189">
        <property type="entry name" value="Cdc37_Hsp90-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013855">
        <property type="entry name" value="Cdc37_N_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12800">
        <property type="entry name" value="CDC37-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12800:SF4">
        <property type="entry name" value="HSP90 CO-CHAPERONE CDC37"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08564">
        <property type="entry name" value="CDC37_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08565">
        <property type="entry name" value="CDC37_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03234">
        <property type="entry name" value="CDC37_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01069">
        <property type="entry name" value="CDC37_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01070">
        <property type="entry name" value="CDC37_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01071">
        <property type="entry name" value="CDC37_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101391">
        <property type="entry name" value="Hsp90 co-chaperone CDC37"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0143">Chaperone</keyword>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cdc37 N-terminal" evidence="10">
        <location>
            <begin position="2"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="domain" description="Cdc37 Hsp90 binding" evidence="9">
        <location>
            <begin position="183"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="domain" description="Cdc37 C-terminal" evidence="8">
        <location>
            <begin position="371"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="171"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="139"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="173"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="223"/>
            <end position="232"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00031396"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM01069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM01070"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM01071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="OBZ82594.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="445" mass="50531" checksum="EFBE38B4F87C8481" modified="2016-11-30" version="1">MPLDYSKWDNLEISDDSDIEVHPNVDKRSMIKWKQEALHRERAERRAKMDYLNQFVPQQKNVLKKVQEFIDMLKNSSDASEAIQRVLKALDQHQTEASQLPAPKDPNMMDMSQVFGAMKDQIKTGLETTSPEQVKSSLLERFEQTQATVQKTVDQASAELDKLTKEASKKLTSENMFTSEKSNKTVINKSKPTPTPKKKTTTKVVETLNPNATMKDLSLQDQASDDADDEDEDIEMSPKATQFSKLRGFEDSYKFLLKHADIINEKTSDSILGQAFTAQLKGEEEYAKNCVIQSLMLQYCGQLGKDGVNLFFSRMSAPNTQGRKMFFDDVDKTYGRIQTRCAEIAAEEVTEQNGVETIQLQPMGDGSQLTIRIPTPEDQEPYKIFNDMPTTFQEALKTGKLEEINKVLEKLPVPEAEQLVHICSEYGFLDVEGEVIDETQQQQQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N5P5</accession>
    <name>A0A1C7N5P5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Paladin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">PALD1_0</name>
        <name evidence="2" type="ORF">A0J61_07633</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000526">
        <property type="protein sequence ID" value="OBZ84318.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="InParanoid" id="A0A1C7N5P5"/>
    <dbReference type="OrthoDB" id="66369at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd14496">
        <property type="entry name" value="PTP_paladin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.190.10">
        <property type="entry name" value="Protein tyrosine phosphatase superfamily"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029021">
        <property type="entry name" value="Prot-tyrosine_phosphatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050561">
        <property type="entry name" value="PTP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23339">
        <property type="entry name" value="TYROSINE SPECIFIC PROTEIN PHOSPHATASE AND DUAL SPECIFICITY PROTEIN PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14566">
        <property type="entry name" value="PTPlike_phytase"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM01301">
        <property type="entry name" value="PTPlike_phytase"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52799">
        <property type="entry name" value="(Phosphotyrosine protein) phosphatases II"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="63"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="626"/>
            <end position="649"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ84318.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="1518" mass="172059" checksum="F3D1EA033982A09E" modified="2016-11-30" version="1">MSHSSSPRIPSEPGSASGSPHIQSKVISSPQQDQPTRRFVPPRIDHSNNLSFRHNLLLSSASSSRSESSLGDDQSTDDHVSQDPRKLLNAAKNLIRNRHGSVLARNTILKMDHFEKAINTKLDFHLQGAPNFRMANLNVYGVAQPTAIGLSTVLAILNCHPNSASDAACTWFLTREEPLIYINGYPYVLREYADPLQNMISFLGISARRLEKLEERLKADVQREAKAMGGLILVHQELPDSTIVPCFIAADQVQTPRELFEQFKDQNYRVSYFRIPISPEQAPEDNYFDEYVRVIKSLKPTDPLIFNCGMGVVRTTVGIVLAQIIRRTQLIEMNCPDPFPLSGYKYDQINESTARALSHELFRGWEGADALQSQNHALMRLMYILEKGLDSKMSPRSAIEWALERGPMIENLKEAVLGNYQVITSLTAVLDSGNFSKRMLDDVIDQSDSVINLREDILLNRIKQTTKQSTGYESKTSFIAKAGAGIQRYFSLLCFASYINESPDTTFSTKFSDWLKSRTEIWTMLQSIRRKSPKLYLFRPVDDLHRLANHTGIYSASFHCHHRTLGFGPGMFDMIGAGNQVGSVAPELEEFILKSRTGVVLTSQTILKIDFWSAASQLDVDEHNQLQKLPTPGDTNSDEDNNNSMEYKRPQRHHVFLVEGGSNFRRIKHTHVYGIAQPTVDGLRTVIRRLLTDQPKNEQIRWINLREEPIIYINGIPYVLRDRYFTLRNMRVYKGITGNRLEQLEERLKQDVIREVTNSDGRILLHGEDKDGNVLAAWEEVNVKDIMTVREVMLSIAAEVVEELDHDTGANSGNSSSNNSIHSIDSDDVSNEKINLKARSILDYYRLPITSENTPEWCDFDEMRHLISSVDLSKTAIILNCQVGLGRSTLGTIIATLITNWIKPAEKSEHEDSNNRCKYLNYQIVNSLLRVIKNGLEVKRNVDEVIDKCGAFLNLREMIESEHLKAENESDEKKKAAYVRRGVAALHRYFMLLCFGAYLDSTPPDSATSTETFDVWMNKRPEIGTLLHEFNDRDEKLIVPVEKSIGDGMALSSEIMSVVASRHGQVLAQQTILKHDAFPGCQKMSLKEKIEGAYNFRRVPVKDVKLAVKASSKAADESGLSADLERSDDELLEAPFICGCAMPSKDAIKAVLKRMQAGPGGKRKVLWTCLREEPVLYVNRQPYVLRLFQDPLKNLESTGITTDRVEGIEERMKLEAKNECVEYEGRLLLHDEKANDRGEFDLVGMWETVNLEEIETPKEAFQSIINEGYQVDYLRIPITDEQAPIPDVFDELISRTKSAHKGVDVLYNCQMGRGRTSTGMVTACLLAMIMNNDAIFADKNGTIMIDPSTLSRQPSVIMGTGINSIYNSENEESMEESYHNGEFKIILQVISVLTYGKLAKRLTDKAINMCDHMQNLRKAIFDYKLRMDALDDPKSKQYKLIKEVALNYLIRYFYLIVFANYLLEELASKQTENGSQRLEEEQEAICDDKMNESPSFKDWLSSRREITNILRLKPIELD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N657</accession>
    <name>A0A1C7N657_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">RNA-binding protein vts1-like alpha-helical domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">A0J61_07347</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000490">
        <property type="protein sequence ID" value="OBZ84603.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="InParanoid" id="A0A1C7N657"/>
    <dbReference type="OrthoDB" id="2155283at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000932">
        <property type="term" value="C:P-body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000289">
        <property type="term" value="P:nuclear-transcribed mRNA poly(A) tail shortening"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050897">
        <property type="entry name" value="SMAUG/VTS1_RNA-bind"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057327">
        <property type="entry name" value="Vts1_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12515:SF5">
        <property type="entry name" value="PROTEIN SMAUG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12515">
        <property type="entry name" value="STERILE ALPHA MOTIF DOMAIN CONTAINING PROTEIN 4-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25479">
        <property type="entry name" value="Vts1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RNA-binding protein vts1-like alpha-helical" evidence="3">
        <location>
            <begin position="60"/>
            <end position="103"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF25479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OBZ84603.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="163" mass="19075" checksum="56BBE5B3A24330AD" modified="2016-11-30" version="1">MHPSDFSSSKQGRPISSYLDCNDSVDGNALGTWYEDLEEYEDNLEKMATANLDQSFQDELQHVNQWFGFLSDAEKTATIYALLQHSSQVQIKFFIRMLQEMRKSNXPARSNSYMSDDWDTTLDDLCHLFPRLDRRYVDDFLRSARGDFYVAKNMILDMIMKMP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N6D5</accession>
    <name>A0A1C7N6D5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Protein trichome birefringence-like 13</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">TBL13_0</name>
        <name evidence="4" type="ORF">A0J61_07353</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the PC-esterase family. TBL subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000491">
        <property type="protein sequence ID" value="OBZ84597.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N6D5"/>
    <dbReference type="STRING" id="101091.A0A1C7N6D5"/>
    <dbReference type="InParanoid" id="A0A1C7N6D5"/>
    <dbReference type="OrthoDB" id="630188at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016413">
        <property type="term" value="F:O-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029962">
        <property type="entry name" value="TBL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026057">
        <property type="entry name" value="TBL_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32285:SF48">
        <property type="entry name" value="PROTEIN TRICHOME BIREFRINGENCE-LIKE 19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32285">
        <property type="entry name" value="PROTEIN TRICHOME BIREFRINGENCE-LIKE 9-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13839">
        <property type="entry name" value="PC-Esterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="14"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="domain" description="Trichome birefringence-like C-terminal" evidence="3">
        <location>
            <begin position="129"/>
            <end position="388"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OBZ84597.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="394" mass="44836" checksum="C9DA3361F98FAD4D" modified="2016-11-30" version="1">MLENSKSKNDKSKLIYAISIFGCLALWITVYNQPAGFLSSQPEILASDIDETRPLCTPEDFNSGRWIYSPLPLKANFSATDIANVAGYHCLKKFAHRCFRRPGENELTRAKQIMDYKWQPDSCDMLEMNPKRLADHFVSHPILFVGDSITQLQYESLGCLLGNHLPNRHPTGGNLNGGNSKIRVNQLAPKDKETAAIAYIRSDYLLRLDDLKVISPFEPVGVQLGSGENYPWVHALSEFDYVVINTGPHWHPNLHWGPNASEEELLDAFKRAMTNVLDYLKEHVKPHQKVWIRTTPYGHARCSRFKEPQPNPLAPSGQTGEYEWHLFDRFDQIWKDLLTSVGDDGRFGMFDIAGLSNQRGDAHSKPDVDCLHTCIPGPVDDWNRLLYHEVMKHQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N705</accession>
    <name>A0A1C7N705_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Protein UXT</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_07040</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UXT family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000456">
        <property type="protein sequence ID" value="OBZ84910.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N705"/>
    <dbReference type="STRING" id="101091.A0A1C7N705"/>
    <dbReference type="InParanoid" id="A0A1C7N705"/>
    <dbReference type="OrthoDB" id="433124at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016592">
        <property type="term" value="C:mediator complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003714">
        <property type="term" value="F:transcription corepressor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000122">
        <property type="term" value="P:negative regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd23158">
        <property type="entry name" value="Prefoldin_UXT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.370">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009053">
        <property type="entry name" value="Prefoldin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004127">
        <property type="entry name" value="Prefoldin_subunit_alpha"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003994">
        <property type="entry name" value="UXT"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00293">
        <property type="entry name" value="prefoldin subunit alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13345">
        <property type="entry name" value="MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13345:SF9">
        <property type="entry name" value="PROTEIN UXT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02996">
        <property type="entry name" value="Prefoldin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01502">
        <property type="entry name" value="UXTPROTEIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46579">
        <property type="entry name" value="Prefoldin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="99"/>
            <end position="126"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007666"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ84910.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="147" mass="16793" checksum="7B277E4BBD18C667" modified="2016-11-30" version="1">MEDPVKKDLGALLKKYDEFITHKLKPSLKKELDERDAIFNSIAEYQKLNTQIETIQGNNLKELKTMVDLGSQFYVQAHVPDTQYIYVNVGFGFHVQFTLDEAKAFIAKKEKQLQSLADKHSKEADKIRAHIKMALEAISEIIVNQAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N7A3</accession>
    <name>A0A1C7N7A3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_07021</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000454">
        <property type="protein sequence ID" value="OBZ84927.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N7A3"/>
    <dbReference type="InParanoid" id="A0A1C7N7A3"/>
    <dbReference type="OrthoDB" id="2279197at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ84927.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="128" mass="14884" checksum="7D4F2382D41C4D20" modified="2016-11-30" version="1">MTSIRFPPATLSSKLSTKMLRKTSDQVEPSYLEDVAYWPSDLNESDNESECYTTTTSSTSGKHNIYQFYRQQQALHQLEPILCIQSVDSQIVSVEPKKKKKRLVLIKRLMMKMRDAAERPFQSIDHHF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N7T4</accession>
    <name>A0A1C7N7T4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="10">E3 ubiquitin-protein ligase DMA2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">DMA2_1</name>
        <name evidence="10" type="ORF">A0J61_07266</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000481">
        <property type="protein sequence ID" value="OBZ84689.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N7T4"/>
    <dbReference type="FunCoup" id="A0A1C7N7T4">
        <property type="interactions" value="9"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N7T4"/>
    <dbReference type="InParanoid" id="A0A1C7N7T4"/>
    <dbReference type="OrthoDB" id="687730at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032153">
        <property type="term" value="C:cell division site"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000151">
        <property type="term" value="C:ubiquitin ligase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016567">
        <property type="term" value="P:protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006511">
        <property type="term" value="P:ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.200.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000253">
        <property type="entry name" value="FHA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008984">
        <property type="entry name" value="SMAD_FHA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15067:SF7">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE DMA1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15067">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE RNF8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00498">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17123">
        <property type="entry name" value="zf-RING_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00240">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49879">
        <property type="entry name" value="SMAD/FHA domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50006">
        <property type="entry name" value="FHA_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <keyword evidence="4" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 6" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="FHA" evidence="8">
        <location>
            <begin position="94"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="domain" description="RING-type" evidence="9">
        <location>
            <begin position="223"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="33"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="41"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OBZ84689.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="357" mass="39571" checksum="F4D68E6900D471A2" modified="2016-11-30" version="1">MASHYTNEENQHEEDEPRGLIGNTLRRSLGNSALFGRRSSRSSPPAAIRPASEIQLDDKRQKTIRIRIVPSIENPSRSLIFSIIERDLEVGRMIKIGRFTDRSSIQNHISFKSKVVSRSHCEIWQSHHGKVFLKDTKSSSGTFVNHVRLSPANTESRPVEIHDGDLVQLGVDYQGGYEEVYRAVKMRFEVNRTKQERPLSYSVSAYKHLRNLTNDHVTDVEECCICLYALAPFQALFVAPCAHSYHFKCIKPLFESYPGFQCPICRTYSDLDASVAIEAEEVVEKFGLRTSSTATTLSFVDSKQRTHEASSVLPHAPLSSVSSSPATPVAEPSLSASLVGCSASLSGLVSSVGIEGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N7Y5</accession>
    <name>A0A1C7N7Y5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_06719</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000420">
        <property type="protein sequence ID" value="OBZ85223.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N7Y5"/>
    <dbReference type="InParanoid" id="A0A1C7N7Y5"/>
    <dbReference type="OrthoDB" id="2288107at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="478"/>
            <end position="500"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ85223.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="500" mass="57815" checksum="C896A301BE1379D2" modified="2016-11-30" version="1">MSNSQPHEYTFPTGLDPSVSAFFSNHNVNEWTFEKYKEFCLHDNPTTQMNSIITHYQDNLIKIINNKDVPINIKGKAGNLRASIKGKATEKHSPQNVYNVNIKTNHGTIYGDVFNNNDPYRSDKRQKTDHINDKSSDWKINKQEDVWEAVRQYLEASITHDFCLEKSHIIQCGYSIKCDPSIPDELWAYFKDDEYTISTPFQSCSRYTTSVLSAMKKNELKAIQKVIRSLEAADDIPSKKQTFVEEFFHVCLYIYRKPNLYERLSVNETGFNHSFIWLVMEFVIDSIPDMPLKLYPAEYILKCSKEEYKTDACILLEEDELSILETSGKILLDDNSKYGSDHIKVHYGALSIFNSLYKKYCWASEAAALKLQVPFLHARHDQIHLWSLELCSSELYCSKRIFKTKVPKSMADSQDILSLGNLSWSYRRLLEGATRVVKMMKEEHEEYLLQKVLSNEAESRTSLSTLLKLDIQKPVKGPGYSLLLPEENDEEQSVKYSEAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N831</accession>
    <name>A0A1C7N831_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="15">Phosphoglucomutase-2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="15" type="primary">Pgm2</name>
        <name evidence="15" type="ORF">A0J61_06667</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 11">Belongs to the phosphohexose mutase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000413">
        <property type="protein sequence ID" value="OBZ85290.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N831"/>
    <dbReference type="FunCoup" id="A0A1C7N831">
        <property type="interactions" value="230"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N831"/>
    <dbReference type="InParanoid" id="A0A1C7N831"/>
    <dbReference type="OrthoDB" id="8300170at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008973">
        <property type="term" value="F:phosphopentomutase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006006">
        <property type="term" value="P:glucose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046115">
        <property type="term" value="P:guanosine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006148">
        <property type="term" value="P:inosine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006166">
        <property type="term" value="P:purine ribonucleoside salvage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd05799">
        <property type="entry name" value="PGM2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.120.10:FF:000035">
        <property type="entry name" value="Pgm3p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.120.10">
        <property type="entry name" value="Alpha-D-Glucose-1,6-Bisphosphate, subunit A, domain 3"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.310.50">
        <property type="entry name" value="Alpha-D-phosphohexomutase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005844">
        <property type="entry name" value="A-D-PHexomutase_a/b/a-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016055">
        <property type="entry name" value="A-D-PHexomutase_a/b/a-I/II/III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005845">
        <property type="entry name" value="A-D-PHexomutase_a/b/a-II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005846">
        <property type="entry name" value="A-D-PHexomutase_a/b/a-III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036900">
        <property type="entry name" value="A-D-PHexomutase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016066">
        <property type="entry name" value="A-D-PHexomutase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005841">
        <property type="entry name" value="Alpha-D-phosphohexomutase_SF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45745:SF1">
        <property type="entry name" value="PHOSPHOGLUCOMUTASE 2B-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45745">
        <property type="entry name" value="PHOSPHOMANNOMUTASE 45A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02878">
        <property type="entry name" value="PGM_PMM_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02879">
        <property type="entry name" value="PGM_PMM_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02880">
        <property type="entry name" value="PGM_PMM_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00509">
        <property type="entry name" value="PGMPMM"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55957">
        <property type="entry name" value="Phosphoglucomutase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53738">
        <property type="entry name" value="Phosphoglucomutase, first 3 domains"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00710">
        <property type="entry name" value="PGM_PMM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0313">Glucose metabolism</keyword>
    <keyword evidence="9" id="KW-0413">Isomerase</keyword>
    <keyword evidence="8 11" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7 11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Alpha-D-phosphohexomutase alpha/beta/alpha" evidence="12">
        <location>
            <begin position="44"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="domain" description="Alpha-D-phosphohexomutase alpha/beta/alpha" evidence="13">
        <location>
            <begin position="211"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="domain" description="Alpha-D-phosphohexomutase alpha/beta/alpha" evidence="14">
        <location>
            <begin position="328"/>
            <end position="452"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010231"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022526"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU004326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF02878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF02879"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF02880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="OBZ85290.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="600" mass="67491" checksum="3B38D82C2B7A3B51" modified="2016-11-30" version="1">MTSIEVLVEKWLSLDKNQDTRNEILELQKANNIQELEKRLSSRIEFGTAGLRARMEAGFSRMNDLTVLQASQGLAVYIEQHVKDAKSRGVVVGHDHRHHSLDFARLTAAAFLQRGFKVWFYHDLVHTPLVPYTIKKLNAAGGVMITASHNPKDDNGYKVYWENACQIIPPHDEGIAQSILDHLEPWGWEYDLVNTKTDLVSDPTDLGVIDSYFKEVEQLCQNRSDNESSPVKFAYTAMHGVGTPFAKRAFACFGLPAFELVQEQIMPDPDFPTVAFPNPEEGKGSLSLAMQTADRTGAQIILANDPDADRLAIAEKRSDTGEWHIFTGNQIGSILGAASFEKAKDQYPPSQLAMVASTVSSKFLARMAEVEGFIFEDALTGFKWIGNTAMRLEQEGKRVIFAYEEAIGFTIGDIVKDKDGVSALAFFSEWAVQLYKRGMTVYEYLESLYKKYGYFVSENSYFICHDKQKIAAIFDRIRFGETKQKQDQSKYGYALNYPTTVGGHKVIGIRDLTIGYDNSKPNNEPTMPVSASSEMITFRLENNTVFTIRTSGTEPKIKYYSELRGDNEEQAKLDLHKVVEAIGEELMEYTKNGLAKKKED</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N994</accession>
    <name>A0A1C7N994_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="14">Ergosterol biosynthetic protein 28</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">ERG28</name>
        <name evidence="14" type="ORF">A0J61_06238</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ERG28 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000368">
        <property type="protein sequence ID" value="OBZ85702.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="FunCoup" id="A0A1C7N994">
        <property type="interactions" value="224"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N994"/>
    <dbReference type="InParanoid" id="A0A1C7N994"/>
    <dbReference type="OrthoDB" id="6485510at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030674">
        <property type="term" value="F:protein-macromolecule adaptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016126">
        <property type="term" value="P:sterol biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005352">
        <property type="entry name" value="Erg28"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15451:SF19">
        <property type="entry name" value="ERGOSTEROL BIOSYNTHETIC PROTEIN 28 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15451">
        <property type="entry name" value="ERGOSTEROL BIOSYNTHETIC PROTEIN 28-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03694">
        <property type="entry name" value="Erg28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="3" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="9" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="10 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0752">Steroid biosynthesis</keyword>
    <keyword evidence="12" id="KW-0753">Steroid metabolism</keyword>
    <keyword evidence="8" id="KW-0756">Sterol biosynthesis</keyword>
    <keyword evidence="11" id="KW-1207">Sterol metabolism</keyword>
    <keyword evidence="4 13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 13" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="92"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="116"/>
            <end position="133"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005377"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022955"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023166"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="OBZ85702.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="143" mass="16560" checksum="DA79C32474614C6D" modified="2016-11-30" version="1">MEAFYGRFAEVFSTLPEGYLPKWLLFTSALXIFNSVQNFCTSSLTKRVYANKPEEVTPLSGRLFATWTWSVSMIRIYAAFHLQHKFMYDLGIWTYVIALTHFASELLVFKGCKLNGPYMSPIIVAVTSLVWLTQVKDQYVKFY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N9F5</accession>
    <name>A0A1C7N9F5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Ribosomal RNA-processing protein 17</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">rrp17</name>
        <name evidence="6" type="ORF">A0J61_06245</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the RRP17 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000368">
        <property type="protein sequence ID" value="OBZ85711.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N9F5"/>
    <dbReference type="STRING" id="101091.A0A1C7N9F5"/>
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    <dbReference type="OrthoDB" id="551633at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019186">
        <property type="entry name" value="Nucleolar_protein_12"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14577">
        <property type="entry name" value="NUCLEOLAR PROTEIN 12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14577:SF0">
        <property type="entry name" value="NUCLEOLAR PROTEIN 12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09805">
        <property type="entry name" value="Nop25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="76"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="102"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="109"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="122"/>
            <end position="132"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OBZ85711.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="150" mass="17626" checksum="8E9303911D9C0F25" modified="2016-11-30" version="1">MKVKNVKGKGKFKNSDVLSAGSKVYAKKRKAKQETVEYVEFDPAKRSEFLTGFHKRKMERKKKTIEKYAQLEREEKLRNRKEAREQRQRMADKNVQEMAAMLRGHVDEPDSFQSEEDDEEEDKKPVVQEFKNKSTLTTVTVIEDLDLDDP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N9Q2</accession>
    <name>A0A1C7N9Q2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_06621</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000408">
        <property type="protein sequence ID" value="OBZ85336.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N9Q2"/>
    <dbReference type="InParanoid" id="A0A1C7N9Q2"/>
    <dbReference type="OrthoDB" id="10624556at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="35"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="82"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="35"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="111"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="155"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="181"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="215"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="231"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="254"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="278"/>
            <end position="292"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ85336.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="386" mass="43051" checksum="83DDA0726CEFE141" modified="2016-11-30" version="1">MSTDVLTPEVQTLLSYVSNRPRVMRVSDLMKAEFSDELKDDKQTPESDEEDLDDQKASLALKMLEMLDKNPSDEEALVLKKEDIATIENLSIEEDLQKEKVTNYDEATEDQAVSESSTNKQAPEEQDTERSQTTEDQDVEEQNEIVQTVKEKASSDSVLKSVSTKGKHKPSSGTDMSNSSDDERKTNVTEAFADKDSDYAELLYGHEDTSFLDVGADDEEDPEEDEESSSNGAQESEVTKSQNKKQSGFTDIGYNEDEEEEEDEEEDEEEEELEEPEAATATATDATFKAAAFDSNSNNYINRWDQPPSKNPNDSPFSPVPEKKIEMPASRKNTTVVQHNVRGNHTASSSPSEVNFFSNNAHSNLALSWVVSSSFIALTVFFTYCA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NA13</accession>
    <name>A0A1C7NA13_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">phosphoinositide 5-phosphatase</fullName>
            <ecNumber evidence="4">3.1.3.36</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">syj1</name>
        <name evidence="11" type="ORF">A0J61_06158</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the synaptojanin family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">In the central section; belongs to the inositol 1,4,5-trisphosphate 5-phosphatase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.36" evidence="4"/>
    <dbReference type="EMBL" id="LUGH01000358">
        <property type="protein sequence ID" value="OBZ85798.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NA13"/>
    <dbReference type="FunCoup" id="A0A1C7NA13">
        <property type="interactions" value="279"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NA13"/>
    <dbReference type="InParanoid" id="A0A1C7NA13"/>
    <dbReference type="OrthoDB" id="405996at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990651">
        <property type="term" value="F:inositol-1,2,4,5,6-pentakisphosphate 5-phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990649">
        <property type="term" value="F:inositol-1,2,4,5-tetrakisphosphate 5-phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052659">
        <property type="term" value="F:inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052658">
        <property type="term" value="F:inositol-1,4,5-trisphosphate 5-phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990650">
        <property type="term" value="F:inositol-2,4,5,6-tetrakisphosphate 5-phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990640">
        <property type="term" value="F:inositol-2,4,5-triphosphate 5-phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990648">
        <property type="term" value="F:inositol-4,5,6-triphosphate 5-phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030487">
        <property type="term" value="F:inositol-4,5-bisphosphate 5-phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034485">
        <property type="term" value="F:phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043813">
        <property type="term" value="F:phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004439">
        <property type="term" value="F:phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046856">
        <property type="term" value="P:phosphatidylinositol dephosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.10.10:FF:000029">
        <property type="entry name" value="Inositol polyphosphate 5-phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.10.10">
        <property type="entry name" value="Endonuclease/exonuclease/phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036691">
        <property type="entry name" value="Endo/exonu/phosph_ase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046985">
        <property type="entry name" value="IP5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000300">
        <property type="entry name" value="IPPc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002013">
        <property type="entry name" value="SAC_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11200">
        <property type="entry name" value="INOSITOL 5-PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11200:SF257">
        <property type="entry name" value="PHOSPHOINOSITIDE 5-PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22669">
        <property type="entry name" value="Exo_endo_phos2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02383">
        <property type="entry name" value="Syja_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00128">
        <property type="entry name" value="IPPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56219">
        <property type="entry name" value="DNase I-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50275">
        <property type="entry name" value="SAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-0653">Protein transport</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="domain" description="SAC" evidence="10">
        <location>
            <begin position="141"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="882"/>
            <end position="905"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="948"/>
            <end position="1034"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="973"/>
            <end position="1001"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="1002"/>
            <end position="1012"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="1021"/>
            <end position="1034"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009678"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013044"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50275"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="OBZ85798.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="1034" mass="117544" checksum="C66396F11957B66D" modified="2016-11-30" version="1">MQSHLLLREYPRALALRPTVLEEAPSGVLVFEEYQGSDTRAITKLYPPSEFEDAQWHILNSRPVFGCLGLITVQSECFVAIVTDCVSVGRIRAGEEVYKIQSVSFYSLSSARYDDLDDPSGNWDDEWEPNTTAIQHPCSQLQKLFSVGSFYFTPDFDLTKTVQARTSVASLGVHAFDEHFLWNQFLISGLLEFRSKLDRKSQMDLDRGGFLVLAIRGFVGTETVEIDHERYEMSVISKLSCQRAGTRFNSRGIDDNGHVANFVETETILYSDRICYSYTQIRGSVPVFWEQQGMQLVQHKIQISRGPGATQPAVKRHFDELINRYHCVSNINLLSQKETSAAGESVLSQAFNTAVHQLNYDPQLVQMVNFDLHAECRGGNYDNVSLLMRDIRESMENYGFFLMDTEDNQIICTQKGVFRTNCMDCLDRTNLVQNEISRKALLDFLHAKFRQQQFSFGNLVSRHSHLWAENGDSLSKIYAGTGALKSAFTRTGKVTFMNVLSDATRSVNRFYINNFQDKARQEVIDQLLGKLANQTMIMIYDPISDNVTRQLSTRIKEYSRNRKITIFAGTYNLNGKRFKGESLEPWLLDHLKLNKEEPDLYVIGFQEIVELSPQQVMATDAEKRLVWEQQIEKTLNQRSGSKFRYTLLRSNQLVGAALIVFAKSTIVDEIRNVETSIKKTGIMGIAGNKGAVAIRMDYGDTSFCFVAAHFASGHSNVDDRNTDFHTINEGLRFLRGKTIDSHDNIIWVSDFNYRVSLPNEEVRLYARDGNIEALLKQDQLRREMYEGRVFFGYQEGDITFLPTYKYDNGTDVYDTSEKQRIPGWTDRILYKGKELKQLQYSRAELYTSDHRPVFALFETNIVTLDQEAKSKLQRELYQSLSSIEVKPSSSPPELPKRKNTIPTTKPLKLSDSFVDTLIDVSLDSNEYPPPSSDTKKWWEDGQEIPKADIGRATSHNPFEEDGFVLTGGPNSLKFPSSLQSDSEWTPLSPSSYQGPSLMNGNIQQQQQTTKSSSPPPITTSANVSSVIGFWNNKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NA35</accession>
    <name>A0A1C7NA35_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Quinidine resistance protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">QDR1</name>
        <name evidence="9" type="ORF">A0J61_07735</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000540">
        <property type="protein sequence ID" value="OBZ84214.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NA35"/>
    <dbReference type="STRING" id="101091.A0A1C7NA35"/>
    <dbReference type="InParanoid" id="A0A1C7NA35"/>
    <dbReference type="OrthoDB" id="440553at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1720.10">
        <property type="entry name" value="Multidrug resistance protein D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502:SF51">
        <property type="entry name" value="QUINIDINE RESISTANCE PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="64"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="104"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="129"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="159"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="8">
        <location>
            <begin position="64"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OBZ84214.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="190" mass="20936" checksum="C24BB0C82A749D0B" modified="2016-11-30" version="1">MTSTKSLSELESNRFTSSTISDESNEKVSNVDLSHQNNNMQQIEEKKQKKEPYTIFTMPQQIRILTITAFTAAISPLTASIYLPSLLQIQEDLMTTTESVNLTVTAYMVMQAISPTFWGTIADSYGRRVVLISTMFIYCCASIGLALSPNYVALLLFRMLQAFGSSSVIAVGAGVLGDIADSKKLVWIKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NAW8</accession>
    <name>A0A1C7NAW8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">GRIP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_05683</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000314">
        <property type="protein sequence ID" value="OBZ86265.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NAW8"/>
    <dbReference type="STRING" id="101091.A0A1C7NAW8"/>
    <dbReference type="InParanoid" id="A0A1C7NAW8"/>
    <dbReference type="OrthoDB" id="1926336at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000237">
        <property type="entry name" value="GRIP_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01465">
        <property type="entry name" value="GRIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00755">
        <property type="entry name" value="Grip"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50913">
        <property type="entry name" value="GRIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GRIP" evidence="2">
        <location>
            <begin position="226"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="4"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="209"/>
            <end position="236"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ86265.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="281" mass="33097" checksum="A1E3E3DE5AECB813" modified="2016-11-30" version="1">MVTTNKLSNNKKVLQAQVTRLTNEIEELYLEKEESKKNVLHFMQEADLARQEAKRALETLDQSTVLSSAWTRISNLDDTCLTQLLTLLDHHAVDEWAQLRSDHVSLQSTLDQTRDEVHATRVALEEETKRANLMKKRWQNAEYQLEKAEHIIDSNKMTQEKEIRQEYQSKLNQSEQSQLHWKNQCEKLISQNALYEEQTKASKAKEIHLMLVNKTLKQEIRKLNREERELVNLEYLRNVILKFLERKNTRAQLVPILSTLLQCSQEDQTRLFQLTQNTITS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NAZ4</accession>
    <name>A0A1C7NAZ4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">histone acetyltransferase</fullName>
            <ecNumber evidence="3">2.3.1.48</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="primary">GCN5_0</name>
        <name evidence="16" type="ORF">A0J61_06143</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the acetyltransferase family. GCN5 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.48" evidence="3"/>
    <dbReference type="EMBL" id="LUGH01000357">
        <property type="protein sequence ID" value="OBZ85806.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NAZ4"/>
    <dbReference type="FunCoup" id="A0A1C7NAZ4">
        <property type="interactions" value="54"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NAZ4"/>
    <dbReference type="InParanoid" id="A0A1C7NAZ4"/>
    <dbReference type="OrthoDB" id="1937912at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000123">
        <property type="term" value="C:histone acetyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010484">
        <property type="term" value="F:histone H3 acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05509">
        <property type="entry name" value="Bromo_gcn5_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.630.30:FF:000004">
        <property type="entry name" value="Histone acetyltransferase KAT2A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.920.10">
        <property type="entry name" value="Bromodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001487">
        <property type="entry name" value="Bromodomain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036427">
        <property type="entry name" value="Bromodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018359">
        <property type="entry name" value="Bromodomain_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037800">
        <property type="entry name" value="GCN5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45750">
        <property type="entry name" value="GH11602P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45750:SF3">
        <property type="entry name" value="HISTONE ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00439">
        <property type="entry name" value="Bromodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00503">
        <property type="entry name" value="BROMODOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00297">
        <property type="entry name" value="BROMO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47370">
        <property type="entry name" value="Bromodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00633">
        <property type="entry name" value="BROMODOMAIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50014">
        <property type="entry name" value="BROMODOMAIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0010">Activator</keyword>
    <keyword evidence="11" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="7 12" id="KW-0103">Bromodomain</keyword>
    <keyword evidence="5" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0804">Transcription</keyword>
    <keyword evidence="6" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="4 16" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="15">
        <location>
            <begin position="310"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="domain" description="Bromo" evidence="14">
        <location>
            <begin position="550"/>
            <end position="620"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="116"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="116"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="13">
        <location>
            <begin position="142"/>
            <end position="211"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008607"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="OBZ85806.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="642" mass="74726" checksum="0121EA15FEA0EA7E" modified="2016-11-30" version="1">MVASSSLPLFPQLAEMNNEEKYGIIARFIPCDLCSGCKGWHPYQNDNSQTDCQCGHDAFHHVNQGQDLNRRLKVALRLIELLEEKGKLDDYDYEDEDISSLKKQILFNATLESEDLKRDRHDQEEEDMIEHNGMKRLKVSQESEEEVENDDDEEEEEEEEEEGEEEEEENEEEENENENEEEDEEDEEEEQQLQQETIDEDEEEDEEEDQKVEDNLKSSNENFAPMDVVKSPTINLPKEEEDLMDRLPMKPKEETNDTVTHVVLNGTEKEDESLEEENEIHRLIKELKPKETIETAAMVEERKGEIQVQVVLNDGSRQSMILLTGLKNIFQKQLPKMPKEYIARLVYDRNHRSIALIRPPQKVFGGICYRPFDAQEFAEIVFCAVASTEQVKGYGSFIMNHLKDYVSAHTNVKHFLTYADNYAVGYFKKQGFTTEITLDKRKWVGYIKDYEGGTIMQCTVVPRVKYLQVRDLLGLQKNAILRKIEERSTEHIVFPGLRMPIGKNGKRSIDPMEVPGIVGSGWTPEMDALSNRPRHPPHHNQMLFLVEEMQNYTHSWPFLEPVSIEEVADYYDIIKDPMDLATLEENVKADAYPTMEDFVRDTQKIFDNCRIYNGEDTEYARCSAKLERFFNDKLKALNKKSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NB99</accession>
    <name>A0A1C7NB99_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="17">5-aminolevulinate synthase</fullName>
            <ecNumber evidence="17">2.3.1.37</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="17">5-aminolevulinic acid synthase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="17">Delta-ALA synthase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="17">Delta-aminolevulinate synthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="21" type="primary">hem-1</name>
        <name evidence="21" type="ORF">A0J61_05545</name>
    </gene>
    <organism evidence="21 22">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="21 22" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="21 22">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Catalyzes the synthesis of 5-aminolevulinate (ALA) from succinyl-CoA and glycine, the first and rate-limiting step in heme biosynthesis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="15 17">
            <text>succinyl-CoA + glycine + H(+) = 5-aminolevulinate + CO2 + CoA</text>
            <dbReference type="Rhea" id="RHEA:12921"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57292"/>
            <dbReference type="ChEBI" id="CHEBI:57305"/>
            <dbReference type="ChEBI" id="CHEBI:356416"/>
            <dbReference type="EC" id="2.3.1.37"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 16">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="5 17">Porphyrin-containing compound metabolism; protoporphyrin-IX biosynthesis; 5-aminolevulinate from glycine: step 1/1.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Membrane</location>
            <topology evidence="3">Peripheral membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="4">Mitochondrion inner membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="17">Mitochondrion matrix</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6 16">Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="21">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.37" evidence="17"/>
    <dbReference type="EMBL" id="LUGH01000302">
        <property type="protein sequence ID" value="OBZ86405.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NB99"/>
    <dbReference type="FunCoup" id="A0A1C7NB99">
        <property type="interactions" value="390"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NB99"/>
    <dbReference type="InParanoid" id="A0A1C7NB99"/>
    <dbReference type="OrthoDB" id="10263824at2759"/>
    <dbReference type="UniPathway" id="UPA00251">
        <property type="reaction ID" value="UER00375"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003870">
        <property type="term" value="F:5-aminolevulinate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902117">
        <property type="term" value="P:positive regulation of organelle assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006782">
        <property type="term" value="P:protoporphyrinogen IX biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd06454">
        <property type="entry name" value="KBL_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.640.10:FF:000006">
        <property type="entry name" value="5-aminolevulinate synthase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010961">
        <property type="entry name" value="4pyrrol_synth_NH2levulA_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015118">
        <property type="entry name" value="5aminolev_synth_preseq"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001917">
        <property type="entry name" value="Aminotrans_II_pyridoxalP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004839">
        <property type="entry name" value="Aminotransferase_I/II_large"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050087">
        <property type="entry name" value="AON_synthase_class-II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01821">
        <property type="entry name" value="5aminolev_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13693:SF102">
        <property type="entry name" value="2-AMINO-3-KETOBUTYRATE COENZYME A LIGASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13693">
        <property type="entry name" value="CLASS II AMINOTRANSFERASE/8-AMINO-7-OXONONANOATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00155">
        <property type="entry name" value="Aminotran_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09029">
        <property type="entry name" value="Preseq_ALAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00599">
        <property type="entry name" value="AA_TRANSFER_CLASS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="14 17" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="12 17" id="KW-0350">Heme biosynthesis</keyword>
    <keyword evidence="13" id="KW-0472">Membrane</keyword>
    <keyword evidence="11 17" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="8" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="9 16" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="22" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 17" id="KW-0808">Transferase</keyword>
    <keyword evidence="10" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="5-aminolevulinate synthase presequence" evidence="20">
        <location>
            <begin position="10"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="domain" description="Aminotransferase class I/classII large" evidence="19">
        <location>
            <begin position="138"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="18">
        <location>
            <begin position="52"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="18">
        <location>
            <begin position="52"/>
            <end position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00003076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00005029"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00008392"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00047654"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="RuleBase" id="RU003693"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="RuleBase" id="RU910713"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="Pfam" id="PF00155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="Pfam" id="PF09029"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="EMBL" id="OBZ86405.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="553" mass="59915" checksum="7A4218348C629050" modified="2016-11-30" version="1">MEVALLQAKKSCPFINVASASSLRRLTSGNMNPLITKAKQCPVMGQAISSRSLSTSSVATQTPTKPTKATAVTNSHARGPIDATACVSHQTQKHFDYERFYQEELDKKHKDKSYRYFNNINRLAQKFPRAHTARVTDEVTVWCANDYLGMGRSPVLTDNMKRTLDRYGAGAGGTRNIAGNADLHLRLESELADLHHAEGALVFSSCYVANDATLSTLASKLPGCVIFSDALNHASMIQGMRHSGAPKKIFRHNDMDHLEQLLQSVDPSIPKIIAFESVYSMCGSIGPIRKIVELAKKYGAITFLDEVHAVGMYGPKGAGVAEHLDYDLNAANPARGNGSIMDDIDIYTGTLGKAYGVVGGYIAGSASLVDMIRSYAPGFIFTTSLPPVVVSGALASVQYLKESSAERHLQQMNARTVKSRLGNLGIPVIPNPSHIVPVLVGDAAAAKLASDELLSEHNIYVQSINYPTVPVGEERLRIAPCPGHTPEMVDHLVGSLESIWSRYGFKRIQDWTAEGGRAGVGIQNAVEPTPIWTDKQLGLDKMVEEKVVSTTVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NBW6</accession>
    <name>A0A1C7NBW6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">SUR7 family protein pun1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_07110</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000463">
        <property type="protein sequence ID" value="OBZ84844.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NBW6"/>
    <dbReference type="STRING" id="101091.A0A1C7NBW6"/>
    <dbReference type="InParanoid" id="A0A1C7NBW6"/>
    <dbReference type="OrthoDB" id="2327445at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.140.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009571">
        <property type="entry name" value="SUR7/Rim9-like_fungi"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06687">
        <property type="entry name" value="SUR7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="107"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="139"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="181"/>
            <end position="201"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ84844.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="216" mass="24269" checksum="1047FC2AB838EB0C" modified="2016-11-30" version="1">MSTFSRILEGTASLFIFAAIVLELFTLLGNTYDKPFLRDLYVIRLTQNSTTDFIDLGLWNSCNGTDGQVLYCDIPQPAFIWTNATGIDKFTSDAFDGYSPVFQANFILYWIGVGFTLLAFVFSVMTWSNNRRFDYTKTAIVTFFGFLIMLAVFCITIVMGARIANTAFLSDTTNASHIGPATWTTLGAMVGLLYATAFYCLSCSFRHRDTRKYDNI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NCG2</accession>
    <name>A0A1C7NCG2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_05140</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000270">
        <property type="protein sequence ID" value="OBZ86807.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NCG2"/>
    <dbReference type="InParanoid" id="A0A1C7NCG2"/>
    <dbReference type="OrthoDB" id="10311276at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008889621" evidence="1">
        <location>
            <begin position="21"/>
            <end position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ86807.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="76" mass="7961" checksum="BB91356E002CC5DC" modified="2016-11-30" version="1">MVSVSSFLFCGLALVVAVNALPAPETHSLKENHEFNAIVASNFQVQPAGCTDGCCSSARQCCTLMGGTMKNGKCYT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NCX7</accession>
    <name>A0A1C7NCX7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_04999</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000258">
        <property type="protein sequence ID" value="OBZ86947.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NCX7"/>
    <dbReference type="STRING" id="101091.A0A1C7NCX7"/>
    <dbReference type="InParanoid" id="A0A1C7NCX7"/>
    <dbReference type="OrthoDB" id="2238957at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="274"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="412"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="57"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="285"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="340"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="412"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="427"/>
            <end position="436"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ86947.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="811" mass="92216" checksum="34E1358B5784F337" modified="2016-11-30" version="1">MEITQADQSSYEAIKDRVVTIQKILNDNSNDKTEATETLRDTLDISLRAIELKDQKQAEQAKEIEQLKLKLSQLKHKIETEGVSDNHARLTDMLQQNISRLENERSAQDVQIRGQLAHIKTLERQMQALKKQLDTLKAKPTVTSAMELKRKKEVDGYQIQIEKLKEKLTVTEQAKERLAQKIDQLESELTNEDEQMTYHELYGKYTFYMTENAFLREQLIQLHTRLSEQQLTAKPSTFVDYTIESQRPVLSRFKKPFNNHAKLVTDQKVLLRSSSGLVPPPSNVTQRQKLQKPQKPQTTTTAAIELDTTIIRSRSNSPDIPSSPILPSPSSSLLPPPPSSALVAPSSPPVSISTPVALPTPVPVSEFVTAPELVTESILEPVLEPALSSSVPSLPANKERAKSKLNQSVDVTKISKTSSSIPQKRTVSMDDNRGEEKRQKIVEQKHYEKANSLLESQAILKSEDIKGKMAVSVVAEIDEHYAHMKSSFTIPGKAGLINYGILNVCTITLPKKMDKHEKIYAWYLAMIYKVEPSEFNIILNHLIQKTHDASMQKASASIFKNRFLRLFRLVTVLLRMTDSKERLRVIFYDYLKTPGCAMQMIPCLYNVVVAWKEVFEGDGIMMASIQACTQHIATRLTMPPTVLSIYNRTNTILKWTPLSIKQCIEITMEFIKSDQLKHIFRTNKEKFHQLKFNITRGLELCFIVLNDWKYVYDYIFSVRLWPLLTQEIIYLIVVDLIGTVGRMGIQQSADTKHGVRFIARCLTTVMNQPNPKEIDLKLAAAKSLLNFSDDTSDHKHIVSMLSEVKASFKKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-06-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NDW2</accession>
    <name>A0A1C7NDW2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_04812</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000243">
        <property type="protein sequence ID" value="OBZ87140.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NDW2"/>
    <dbReference type="InParanoid" id="A0A1C7NDW2"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ87140.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="91" mass="10492" checksum="90D6272B31E4EEC7" modified="2016-11-30" version="1">MYLIFLKSFEQKTTSKCTETRSIRRVSSSLQLSSLNTGLKRKLETNMPLRIKDLTFEPAGFASEQKLKNMFSVLVEYQKHQDNTALTTMVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NDY1</accession>
    <name>A0A1C7NDY1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_04646</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000231">
        <property type="protein sequence ID" value="OBZ87313.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NDY1"/>
    <dbReference type="InParanoid" id="A0A1C7NDY1"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="22"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="22"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="46"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="69"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="98"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="118"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="128"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ87313.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="128" mass="14063" checksum="DADBC443BB99A040" modified="2016-11-30" version="1" fragment="single">MQVKSMEGIYQNNLYSQQSPSYILQSGHQADHTSYSNYGNPYHRTSAFSDARSYQPNSSASPPNPHSSPYPAAAANGLNSTNNHYTTDFHHHTNNTHSLNWSHSAPPNNVSWNTVSSPLPPPPNPSNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NE01</accession>
    <name>A0A1C7NE01_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Chondroitinase-AC</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">cslA_0</name>
        <name evidence="8" type="ORF">A0J61_04624</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the polysaccharide lyase 8 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000230">
        <property type="protein sequence ID" value="OBZ87323.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NE01"/>
    <dbReference type="InParanoid" id="A0A1C7NE01"/>
    <dbReference type="OrthoDB" id="5980780at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016837">
        <property type="term" value="F:carbon-oxygen lyase activity, acting on polysaccharides"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.98.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.100">
        <property type="entry name" value="Chondroitin AC/alginate lyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.220.10">
        <property type="entry name" value="Polysaccharide lyase family 8-like, C-terminal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008929">
        <property type="entry name" value="Chondroitin_lyas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011013">
        <property type="entry name" value="Gal_mutarotase_sf_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014718">
        <property type="entry name" value="GH-type_carb-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038970">
        <property type="entry name" value="Lyase_8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011071">
        <property type="entry name" value="Lyase_8-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012970">
        <property type="entry name" value="Lyase_8_alpha_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004103">
        <property type="entry name" value="Lyase_8_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003159">
        <property type="entry name" value="Lyase_8_central_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38481">
        <property type="entry name" value="HYALURONATE LYASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38481:SF1">
        <property type="entry name" value="HYALURONATE LYASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02278">
        <property type="entry name" value="Lyase_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02884">
        <property type="entry name" value="Lyase_8_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08124">
        <property type="entry name" value="Lyase_8_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48230">
        <property type="entry name" value="Chondroitin AC/alginate lyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74650">
        <property type="entry name" value="Galactose mutarotase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49863">
        <property type="entry name" value="Hyaluronate lyase-like, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0456">Lyase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008889642" evidence="4">
        <location>
            <begin position="19"/>
            <end position="747"/>
        </location>
    </feature>
    <feature type="domain" description="Polysaccharide lyase 8 N-terminal alpha-helical" evidence="7">
        <location>
            <begin position="145"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="domain" description="Polysaccharide lyase family 8 central" evidence="5">
        <location>
            <begin position="381"/>
            <end position="627"/>
        </location>
    </feature>
    <feature type="domain" description="Polysaccharide lyase family 8 C-terminal" evidence="6">
        <location>
            <begin position="653"/>
            <end position="714"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006699"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF02278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF02884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF08124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OBZ87323.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="747" mass="82021" checksum="50036C70120C36D2" modified="2016-11-30" version="1">MRSTLATICLLFIGSIYAVVMPTADDMATMKSRRIDHIVKYNSANSTYFLNRWKNTLNENGTWTDIDMTSGCGSRIANWPAQQHLIRVLNLAIGYHETMQPEYLKTSLASLDYWLENDFSEHDCIENSGVASMNCPCGTPGLWSKNWFNQLIGIPSAIGDTCLLLRNELNESQKKSCITIQARAFAKVTSMTQAISVLTAANLLDVADIGITLAMFKDDLEMLKTALEAFYDGITISKTTAGDGIQADGSFIQHNGILYNGNYGKDFASDVLAVFTETVGLDIAPSESALAAFKTLIDGSEWMMIADTKLQQLLWQYSAIGRMVSFKYSDKQSSGGVVLDLKEIAKSAQGSATEKEMQAISDRLNGSPTGNANQGNLIGTRYFYNSDYMVHRTADYVVTLKMYSSRTINSECLNIQNPQGFHMSDGAIFNYITGNEYVDSFGSWDWDLVPGITVDYQGTLLTCSKVKNKGKKKFVGGVTDGNMGIAVMDYLNPLNGNLAFKKTVFFFPSGYAVQVGPTTSKNTTAELITVLDQRFRKGNIYISGELKNTLMSYLSPKTNYLWHDNIGYYFPTAEDIYVDSKPRYANWSKVGISVGADPQQLWSSYIKHPKTNTSGLLTQYIVQPAVSHAAFSANASEGNMPIQLAFHASSPLVNAAYSPANKTIAAAFWTAGTYTTPWSCTIKTDNPCVILLNQLSQHSYRVTVSDPSQSLTSIKLTVTIEGVTKYATYSLPSGNKAGSGVVKTLTF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NFA8</accession>
    <name>A0A1C7NFA8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="11">GTP-binding protein ypt5</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">ypt5</name>
        <name evidence="11" type="ORF">A0J61_04713</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Lipid-anchor</topology>
            <orientation evidence="1">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000236">
        <property type="protein sequence ID" value="OBZ87236.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NFA8"/>
    <dbReference type="FunCoup" id="A0A1C7NFA8">
        <property type="interactions" value="642"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NFA8"/>
    <dbReference type="InParanoid" id="A0A1C7NFA8"/>
    <dbReference type="OrthoDB" id="63533at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005768">
        <property type="term" value="C:endosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016192">
        <property type="term" value="P:vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd01860">
        <property type="entry name" value="Rab5_related"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000464">
        <property type="entry name" value="GTP-binding protein ypt5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001806">
        <property type="entry name" value="Small_GTPase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47978">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00071">
        <property type="entry name" value="Ras"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00449">
        <property type="entry name" value="RASTRNSFRMNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00175">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00176">
        <property type="entry name" value="RAN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00173">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00174">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51419">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51421">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51420">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="8" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-0636">Prenylation</keyword>
    <keyword evidence="5" id="KW-0653">Protein transport</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="178"/>
            <end position="208"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004342"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023289"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="OBZ87236.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="208" mass="22856" checksum="CF06D753A51BC602" modified="2016-11-30" version="1">MSTQQGKTYQFKLVLLGESAVGKSSLVMRFVKDHFDEYRESTIAAFLAQTIPLDDNTTVKFEIWDTAGQERYKSLAPMYYRNANCAVVVYDITQASSLDKAKAWVTELQRQADPNIVIALAGNKSDLEARRAIETKTAQEYADEAGLLFFETSAKTADNVHTLFHAIAKRMPLDQLADNSRGRNRMNARGGGVDLESSGNSAAGGCAC</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NFB0</accession>
    <name>A0A1C7NFB0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Importin subunit alpha</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">IMA</name>
        <name evidence="4" type="ORF">A0J61_04154</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the importin alpha family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000197">
        <property type="protein sequence ID" value="OBZ87791.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NFB0"/>
    <dbReference type="InParanoid" id="A0A1C7NFB0"/>
    <dbReference type="OrthoDB" id="29145at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000225">
        <property type="entry name" value="Armadillo"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23316">
        <property type="entry name" value="IMPORTIN ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00514">
        <property type="entry name" value="Arm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00185">
        <property type="entry name" value="ARM"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0653">Protein transport</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010394"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OBZ87791.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="579" mass="66358" checksum="D658E6892B2F76CB" modified="2016-11-30" version="1">MVISEFEPDDIFKELNQKFASVSLDRNDDQGYREILFDQLPEYRDTLEFSSDYHQCYYAMKNIRRYLTQSVSLERIQHVFDLHLQDRFRTILETPGYDELKYETAWTITNLAYGSTEHAARLIDTGVIDALIYCFRSTENYRVKSQTAWALANISIESPRYRESMAQDNLIGDIAQALSDKCHMIATKLQSAINQDIISQNEQGQIVCHSKPDAEDIKDLTWSLANICRGGFRTVEHWEQYLVAFQAFSQCINFENRDIWSEACWGLSRIFSNMYDYTPFYQSLKLDPTLCPRLVHLLRNQPVDAILPILQTISNFSSGPNELVEILLSADLLNNIWWYLSPDTPHQLRRNAMLTVSNLAAGHEEIVSKVVSNENSMQYVMAHLHIPGHRYHHHAHQWXVSSNAATPDSIEEWRIVKEALWVLSNICTLANDDTLFMLLHEHTKLVYSLASLLHYTDLPEPICSKVVDVLLRIVNRTAQIPGLSEDDINTYAEEMIQEGVMPELNFLSRKLGSYELSSQVDLLHKALLSSTAKVQANAFGLPHQGLSLPGADVRRIVHGFEDGDVRAIENAFHHVKIDQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NFE0</accession>
    <name>A0A1C7NFE0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Reverse transcriptase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_04126</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000195">
        <property type="protein sequence ID" value="OBZ87815.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NFE0"/>
    <dbReference type="STRING" id="101091.A0A1C7NFE0"/>
    <dbReference type="InParanoid" id="A0A1C7NFE0"/>
    <dbReference type="OrthoDB" id="5598377at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000477">
        <property type="entry name" value="RT_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31635">
        <property type="entry name" value="REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31635:SF196">
        <property type="entry name" value="REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00078">
        <property type="entry name" value="RVT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50878">
        <property type="entry name" value="RT_POL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Reverse transcriptase" evidence="1">
        <location>
            <begin position="173"/>
            <end position="283"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ87815.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="283" mass="31953" checksum="58FEB3EF8117ACB7" modified="2016-11-30" version="1">MLDFNELNLLRNSSLYPELSPQLHVVQEQLSSFQQYHVETLALKAGYLKRTASSRFSKSIVPPLEHPSLNRVCQTKEKMLDSDFIFYDKLYSPDPIDFTAAQSLLKSIPPSACISASDSALLVERITFDELVEAFSHFPTTSSPGLDGLSYEIAKLIILHPSCREIALQAFNDALQYGIFPSPWLHTSVFLLPKKGDLSGLKNWRSISLINTDAKVFTRILNARFLLVTDDLINTYQLGFVRGRFITDNGLLVKLLMERARLIHSPAIALLLDQEKAYDRVHP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NGA5</accession>
    <name>A0A1C7NGA5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="8">CDGSH iron-sulfur domain-containing protein 3, mitochondrial</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">Cisd3</name>
        <name evidence="8" type="ORF">A0J61_04174</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000198">
        <property type="protein sequence ID" value="OBZ87769.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NGA5"/>
    <dbReference type="STRING" id="101091.A0A1C7NGA5"/>
    <dbReference type="InParanoid" id="A0A1C7NGA5"/>
    <dbReference type="OrthoDB" id="15717at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.5.90">
        <property type="entry name" value="CDGSH iron-sulfur domain, mitoNEET-type"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052950">
        <property type="entry name" value="CISD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018967">
        <property type="entry name" value="FeS-contain_CDGSH-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042216">
        <property type="entry name" value="MitoNEET_CISD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46491">
        <property type="entry name" value="CDGSH IRON SULFUR DOMAIN PROTEIN HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46491:SF3">
        <property type="entry name" value="CDGSH IRON-SULFUR DOMAIN-CONTAINING PROTEIN 3, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09360">
        <property type="entry name" value="zf-CDGSH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00704">
        <property type="entry name" value="ZnF_CDGSH"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0001">2Fe-2S</keyword>
    <keyword evidence="3" id="KW-0408">Iron</keyword>
    <keyword evidence="4" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="129"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="domain" description="Iron-binding zinc finger CDGSH type" evidence="7">
        <location>
            <begin position="16"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="domain" description="Iron-binding zinc finger CDGSH type" evidence="7">
        <location>
            <begin position="55"/>
            <end position="91"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00034078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00704"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OBZ87769.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="153" mass="17351" checksum="4F5D709F401AAB14" modified="2016-11-30" version="1">MSSATETAPEPVFVQAKPYKVDLEPGKEYYWCTCGESKNQPFCDGSHRAAGQFKPKKITVDEAKTYYLCGCKYTHNEQGFCDGTHRKEEGIKKYNEFLLKANNKLKTQHEEDKQAWEAKLNQAERKQKVASLMAGLSAALLAVGVYIKYTQKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NGS2</accession>
    <name>A0A1C7NGS2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_03635</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000160">
        <property type="protein sequence ID" value="OBZ88312.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NGS2"/>
    <dbReference type="InParanoid" id="A0A1C7NGS2"/>
    <dbReference type="OrthoDB" id="2286114at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="57"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="208"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="311"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="11"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="71"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="110"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="130"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="161"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="178"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="213"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="240"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="262"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="324"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="344"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="379"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="395"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="422"/>
            <end position="439"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ88312.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="486" mass="53541" checksum="93FF315CA5EED631" modified="2016-11-30" version="1">MSNKEVEDSDVSSSPSQSPSDSLFSNFVSVISGAQQSASQEFSRFWDSLCAPKDIHTRDIAKPYSKMQRISSSNSSSSSSNNGADRRKQQIQAIRKRKADTNLYSNIIPDRNRRSCVRDAEIQTDFPSPPDKRKWTSDVEGEARPRKAPRLDIAKSSPASESHKRYEEKGQLPRKVARSSTAPSSPINQIITGSKSVKSLALELEEALAQRLPSESPNRPTHSPIRPTQSPNRPIPSPNKAPQLSSISTNSPNRPIHSPVKTTQSALALSTTTSTSYNKPTLDHSLTSPKTMTPKTMTPISHVTYQLGSDLSDVVGSPEEDEDIRLNKLTESIRRTRTRVSELMASSNASPPKPTHTLSSPRDYDDSSCIPSLTSPTPLSTPPPPPPPPPPPPTFSQSPQRISKVVSSSPSPTQQRHRSPFTYLSPTQSRSTPLKNSALETHPYFKLQQAITSPSKLKPTDKHKAKMRELIQLIPNVRLRKTDTIM</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NGZ5</accession>
    <name>A0A1C7NGZ5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="11">High-affinity glucose transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">HGT1_2</name>
        <name evidence="11" type="ORF">A0J61_03914</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000180">
        <property type="protein sequence ID" value="OBZ88029.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NGZ5"/>
    <dbReference type="FunCoup" id="A0A1C7NGZ5">
        <property type="interactions" value="330"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NGZ5"/>
    <dbReference type="InParanoid" id="A0A1C7NGZ5"/>
    <dbReference type="OrthoDB" id="4142200at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005351">
        <property type="term" value="F:carbohydrate:proton symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000026">
        <property type="entry name" value="MFS quinate transporter QutD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050360">
        <property type="entry name" value="MFS_Sugar_Transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00879">
        <property type="entry name" value="SP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022:SF2">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00171">
        <property type="entry name" value="SUGRTRNSPORT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00216">
        <property type="entry name" value="SUGAR_TRANSPORT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00217">
        <property type="entry name" value="SUGAR_TRANSPORT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0762">Sugar transport</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="21"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="69"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="100"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="124"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="188"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="275"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="320"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="345"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="386"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="425"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="453"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="10">
        <location>
            <begin position="28"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="517"/>
            <end position="542"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="OBZ88029.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="542" mass="59805" checksum="B0D4DA30459A0D82" modified="2016-11-30" version="1">MAPLIPTGSNKIDPNAAKSEAGLVLYLITAFAAIGGFLFGYDFGVTSGVMAMPQFQAYFDPLTPAIKGALNSLMGCGAAFGCLVAGVMSDRFGRRDTIGAAALIFIVGGVLQCASHNIEMQLVGRFISGISVGACSVLSPMYNAELAPKEIRGRLIGFQQLMIDTGLLVSAWLDFGTIYINSDWSWRIPYLVQVVPAVLLAFCPLILPRSPRWLIEKGRTEEALDVLAYVHGKGDRQHPYVLQEFNEINDNVQLENNIAVGSYWEMIKDAKNRRVLWVGCSVAIFQQLTGANVIMYYAAFMFQQAGLKGSMSLMANGLDYAVMVIFCIPGMILVDRVGRVKLMTIGSIGMCACFFIIAGLYGGVGYTEWNEEQLSHVVNMSHNPAAGNAVIVFIFIFVAFYGTTWAPVAWIYIAEIFPLRIRSKGFALASAVLWVGNILVGQVTPILMDSITWGTYIIYGIIGIIMLVWMWLFAPEPKGLSLEEIEVVFHGPLVVTKINYEEYLSAHRDDVEKIRQEQFGQEKEKQMEKQGHEDKDGFDITH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NH86</accession>
    <name>A0A1C7NH86_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">glycerol kinase</fullName>
            <ecNumber evidence="3">2.7.1.30</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">ATP:glycerol 3-phosphotransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="primary">glpK_1</name>
        <name evidence="13" type="ORF">A0J61_05222</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Polyol metabolism; glycerol degradation via glycerol kinase pathway; sn-glycerol 3-phosphate from glycerol: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the FGGY kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.30" evidence="3"/>
    <dbReference type="EMBL" id="LUGH01000276">
        <property type="protein sequence ID" value="OBZ86734.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NH86"/>
    <dbReference type="STRING" id="101091.A0A1C7NH86"/>
    <dbReference type="InParanoid" id="A0A1C7NH86"/>
    <dbReference type="OrthoDB" id="5422795at2759"/>
    <dbReference type="UniPathway" id="UPA00618">
        <property type="reaction ID" value="UER00672"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004370">
        <property type="term" value="F:glycerol kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019563">
        <property type="term" value="P:glycerol catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046167">
        <property type="term" value="P:glycerol-3-phosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006641">
        <property type="term" value="P:triglyceride metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.40:FF:000108">
        <property type="entry name" value="Glycerol kinase, glycosomal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018483">
        <property type="entry name" value="Carb_kinase_FGGY_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018485">
        <property type="entry name" value="FGGY_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018484">
        <property type="entry name" value="FGGY_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10196:SF69">
        <property type="entry name" value="GLYCEROL KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10196">
        <property type="entry name" value="SUGAR KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02782">
        <property type="entry name" value="FGGY_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00370">
        <property type="entry name" value="FGGY_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00445">
        <property type="entry name" value="FGGY_KINASES_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0319">Glycerol metabolism</keyword>
    <keyword evidence="6 10 13" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Carbohydrate kinase FGGY N-terminal" evidence="11">
        <location>
            <begin position="1"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="domain" description="Carbohydrate kinase FGGY C-terminal" evidence="12">
        <location>
            <begin position="77"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="13">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012099"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022798"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00043149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU003733"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF02782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="OBZ86734.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="325" mass="35369" checksum="BDF46F54E6C663D4" modified="2016-11-30" version="1" fragment="single">TNASRTMFMNLKSREWDQRLLDFFGIPSHMLPTIVSSAENYGNMHWGPLEGVPIMGCLGDQQAALVGQKCFDPGEAKNTYGTGAFLLMNVGEAPVISSNGLLSTVGYQFGADGPVSYALEGSISVAGAAVKWLRDNMEIIKTSDDIDKLAAKVKSTGGVFFVTAFSGLFSPYWRDDARGTLVGLTQYTNKHHIARATLEAVCFSTRAILEAMKADGDVPLRLLKADGGMSNSDQCMQIQADVLGIPVVRPGMRDTSALGAAYAAGYAAGIWKNLDDIKKGSIDREDAFNAKWDDEGRERKYKQWEEAVQRSLGWTDVYTPADRIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NHV3</accession>
    <name>A0A1C7NHV3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_03258</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000137">
        <property type="protein sequence ID" value="OBZ88697.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NHV3"/>
    <dbReference type="InParanoid" id="A0A1C7NHV3"/>
    <dbReference type="OrthoDB" id="2284342at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="66"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="66"/>
            <end position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ88697.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="93" mass="10555" checksum="951F3E07E00D27F4" modified="2016-11-30" version="1">METYCSIQNQLLETQTNAADVNTSVTSSPDMEEVDASAPVHSIAVRQRFDWTPPEELAGMLNLKQSPFISSPMNDTQRRELIESYPPMRTMDY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NI76</accession>
    <name>A0A1C7NI76_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_03240</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000136">
        <property type="protein sequence ID" value="OBZ88700.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NI76"/>
    <dbReference type="InParanoid" id="A0A1C7NI76"/>
    <dbReference type="OrthoDB" id="2285859at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd09917">
        <property type="entry name" value="F-box_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="1">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ88700.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="258" mass="29659" checksum="ADACF523FF2B7DD8" modified="2016-11-30" version="1">MDRLPLEVLLEIFSYLSLSSFEALYQVFDRAIVNEALVHKLRCSKTKPLLNLVSTNLHELAAMTANKRNESYLPLYFACFDPIHQLVWTLPDFSGASHYFRVKDAYVSHGKLVIQPHDPQYDQQKVLVSLWDIRKSFPPTRAGTFSGASEYAHIQSQEWTLHQSGCILDSCLIPQHNAIHTETIQCNIKSMDISTKETSVKRPALPSHYLRQTPKNQTKHNLNSPYYVPVYPDPTCGYFMVERLALTIPTLFELFRSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-06-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NJ08</accession>
    <name>A0A1C7NJ08_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_02853</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000114">
        <property type="protein sequence ID" value="OBZ89093.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NJ08"/>
    <dbReference type="InParanoid" id="A0A1C7NJ08"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ89093.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="85" mass="10001" checksum="E7119530DE67BF48" modified="2016-11-30" version="1">MFYPLPWRFINLMILHEPLYSNSRYTLTEDKMAIEVTPTLIGTQKQQLPRPIRIHCGHGDLLLTRQTPLAIYSVCLLHRMSSEYQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NJ38</accession>
    <name>A0A1C7NJ38_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">assimilatory sulfite reductase (NADPH)</fullName>
            <ecNumber evidence="4">1.8.1.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">A0J61_02920</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">This enzyme catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>hydrogen sulfide + 3 NADP(+) + 3 H2O = sulfite + 3 NADPH + 4 H(+)</text>
            <dbReference type="Rhea" id="RHEA:13801"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17359"/>
            <dbReference type="ChEBI" id="CHEBI:29919"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.8.1.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Sulfur metabolism; hydrogen sulfide biosynthesis; hydrogen sulfide from sulfite (NADPH route): step 1/1.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.8.1.2" evidence="4"/>
    <dbReference type="EMBL" id="LUGH01000117">
        <property type="protein sequence ID" value="OBZ89030.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NJ38"/>
    <dbReference type="FunCoup" id="A0A1C7NJ38">
        <property type="interactions" value="293"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NJ38"/>
    <dbReference type="InParanoid" id="A0A1C7NJ38"/>
    <dbReference type="OrthoDB" id="1856718at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009337">
        <property type="term" value="C:sulfite reductase complex (NADPH)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004783">
        <property type="term" value="F:sulfite reductase (NADPH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000103">
        <property type="term" value="P:sulfate assimilation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd06207">
        <property type="entry name" value="CyPoR_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd07034">
        <property type="entry name" value="TPP_PYR_PFOR_IOR-alpha_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.990.10:FF:000010">
        <property type="entry name" value="Sulfite reductase [NADPH] flavoprotein component"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.920">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.970">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.990.10">
        <property type="entry name" value="NADPH-cytochrome p450 Reductase, Chain A, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.80">
        <property type="entry name" value="Nucleotide-binding domain of ferredoxin-NADP reductase (FNR) module"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.920.10">
        <property type="entry name" value="Pyruvate-ferredoxin oxidoreductase, PFOR, domain III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.10">
        <property type="entry name" value="Translation factors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003097">
        <property type="entry name" value="CysJ-like_FAD-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017927">
        <property type="entry name" value="FAD-bd_FR_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001709">
        <property type="entry name" value="Flavoprot_Pyr_Nucl_cyt_Rdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039261">
        <property type="entry name" value="FNR_nucleotide-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023173">
        <property type="entry name" value="NADPH_Cyt_P450_Rdtase_alpha"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001433">
        <property type="entry name" value="OxRdtase_FAD/NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033412">
        <property type="entry name" value="PFOR_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002880">
        <property type="entry name" value="Pyrv_Fd/Flavodoxin_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002869">
        <property type="entry name" value="Pyrv_flavodox_OxRed_cen"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017938">
        <property type="entry name" value="Riboflavin_synthase-like_b-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029061">
        <property type="entry name" value="THDP-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009014">
        <property type="entry name" value="Transketo_C/PFOR_II"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19384">
        <property type="entry name" value="NITRIC OXIDE SYNTHASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19384:SF109">
        <property type="entry name" value="SULFITE REDUCTASE [NADPH] FLAVOPROTEIN COMPONENT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00667">
        <property type="entry name" value="FAD_binding_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00175">
        <property type="entry name" value="NAD_binding_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17147">
        <property type="entry name" value="PFOR_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01855">
        <property type="entry name" value="POR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00371">
        <property type="entry name" value="FPNCR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52343">
        <property type="entry name" value="Ferredoxin reductase-like, C-terminal NADP-linked domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53323">
        <property type="entry name" value="Pyruvate-ferredoxin oxidoreductase, PFOR, domain III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63380">
        <property type="entry name" value="Riboflavin synthase domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52518">
        <property type="entry name" value="Thiamin diphosphate-binding fold (THDP-binding)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52922">
        <property type="entry name" value="TK C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51384">
        <property type="entry name" value="FAD_FR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="10" id="KW-0249">Electron transport</keyword>
    <keyword evidence="8" id="KW-0274">FAD</keyword>
    <keyword evidence="6" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="7" id="KW-0288">FMN</keyword>
    <keyword evidence="9" id="KW-0521">NADP</keyword>
    <keyword evidence="11" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="domain" description="FAD-binding FR-type" evidence="14">
        <location>
            <begin position="656"/>
            <end position="884"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="15">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004774"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00052219"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00059320"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="OBZ89030.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="1038" mass="114573" checksum="4658376970FB51DC" modified="2016-11-30" version="1" fragment="single">LTADSQNSQVRLVDANHAVDYVAYGLSDLVFVYPGSTSGYLGQELPSWTSSVRNAFGELVKVVEMETRAGALQAVQGALADAQNKLVSVLASSQALLSMIPNLHTLAVERQPVVFHVAAQYVDQDLTVSTNVDAVLAARNTGAILLSSSNAQEAHDIGIVAHLIARSVNLPVIHFFNGVTASKEIEKVNLTSFTQLAKLFGTATTSSVAYNEAYEVSKKILAQLNYKPFEYTGAEDAETVLITLNASDATIKQAVSRATSYLNASVGLLSVRVFRPWSDADLIAALPKSARRVVVLEEGAGLYAFNGPLYLDIAAAIRFGPIARDHRPRLISAQADDFAHLHATHIPSLVKEAEQETFINLAAEPFTLSVSDEVIALEKSDAAWSAIFWDVDSNGSSAAAIHSAHLVHAAQPDAPVHARVTRDAYRVGGPVTHTHVTHGSSKFAQHQYIAIHDIAVIREYNTLAHAGKNAAVVLHGPWKHGDELEGILSNEFKFGLTQIDAKLYTVDVSRIAQELGLSTKSTHLVWEAVFLALTQKTSATDQLVQLYDEIQQTGDEEGKRTLAGLVSKVVEAVSEDLSAVELLPPWTILEISDDVLPALPADRLVNEEEEEIAGTVVSEEEEGDGIESDKWHKAAWQLMFNEAYKTETAIRPDLHESTYVIRVSENRRLTPESYDRYVFHIEFDTSDASLKYELGDALGVHGHNDYEEVQAFLNWYGLNGNDVLSVKDAEKGTEEVRTVFQLFSQNLDIFGRPSKKFYESLAAFATDPKEREQLLYLISPEGKEDFKKRVDETVTYEDLLREFTSAKPSVEALAKIVSPIKPRHYSIASSQKMHKNSVHLLIVAVDWEVNGKKRYGQCTRYLSNLRAGDNVTVSIKPSVMKLPPLDTQPVIMAGLGTGMAPFRAFIQERYMAKAAGKKVGPVVLYFGSRHRSMEYLYGEELEAYHADGVLSHMGLAFSRDQKEKIYIQHKMKEDAEMLNEYLMNQNGHFYLCGPTWPVPDVKDAVVYGLTKYGGIDAAKASALIEEWKEKESYILEVY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NJ54</accession>
    <name>A0A1C7NJ54_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Protein BCP1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">BCP1</name>
        <name evidence="4" type="ORF">A0J61_02809</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Involved in nuclear export, actin cytoskeleton organization and vesicular transport.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the BCP1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000111">
        <property type="protein sequence ID" value="OBZ89141.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NJ54"/>
    <dbReference type="FunCoup" id="A0A1C7NJ54">
        <property type="interactions" value="836"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NJ54"/>
    <dbReference type="InParanoid" id="A0A1C7NJ54"/>
    <dbReference type="OrthoDB" id="27543at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025602">
        <property type="entry name" value="BCP1_family"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13261">
        <property type="entry name" value="BRCA2 AND CDKN1A INTERACTING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13261:SF0">
        <property type="entry name" value="BRCA2 AND CDKN1A-INTERACTING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13862">
        <property type="entry name" value="BCCIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF028983">
        <property type="entry name" value="BCP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="2" id="KW-0653">Protein transport</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRNR" id="PIRNR028983"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OBZ89141.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="306" mass="34941" checksum="DF05CD6AF0622103" modified="2016-11-30" version="1">MSPNLKRKAPEDDEEKPLKRASSTQNMASDGEDSDDGLQEIVDVDFDFYNPDDIDYHALKKLLGQLFSSDAELINLGDIADVMIEENQVGTTVKVDDQKSDPYAILSIINMNQQKQKEGVKQLCNYLSNKCPKKNESLATAVKKILSLNSEDQHLGWVVSERFINMPVEIMAPMYSMLQEELKKAVEEKEPYVFEWYMFISKTYKEVASTVDEDEEEKPQQKKAKTSEDSETFYFQSEDEIIAKYAEHQFDFKFTNSDKEQAADSRRAFSDFGIAPSRKLFLVHKPKFDDLVNEIIKTCSSTAAAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NJG4</accession>
    <name>A0A1C7NJG4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Phosphatidylserine decarboxylase proenzyme 2</fullName>
            <ecNumber evidence="12">4.1.1.65</ecNumber>
        </recommendedName>
        <component>
            <recommendedName>
                <fullName evidence="12">Phosphatidylserine decarboxylase 2 beta chain</fullName>
            </recommendedName>
        </component>
        <component>
            <recommendedName>
                <fullName evidence="12">Phosphatidylserine decarboxylase 2 alpha chain</fullName>
            </recommendedName>
        </component>
    </protein>
    <gene>
        <name evidence="15" type="primary">psd3_0</name>
        <name evidence="12" type="synonym">PSD2</name>
        <name evidence="15" type="ORF">A0J61_02673</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer). Plays a central role in phospholipid metabolism and in the interorganelle trafficking of phosphatidylserine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="17">
            <text>a 1,2-diacyl-sn-glycero-3-phospho-L-serine + H(+) = a 1,2-diacyl-sn-glycero-3-phosphoethanolamine + CO2</text>
            <dbReference type="Rhea" id="RHEA:20828"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:57262"/>
            <dbReference type="ChEBI" id="CHEBI:64612"/>
            <dbReference type="EC" id="4.1.1.65"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="12">
            <name>pyruvate</name>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
        </cofactor>
        <text evidence="12">Binds 1 pyruvoyl group covalently per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1">Lipid metabolism.</text>
    </comment>
    <comment type="pathway">
        <text evidence="12">Phospholipid metabolism; phosphatidylethanolamine biosynthesis; phosphatidylethanolamine from CDP-diacylglycerol: step 2/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="12">Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="12">Golgi apparatus membrane</location>
            <topology evidence="12">Peripheral membrane protein</topology>
            <orientation evidence="12">Cytoplasmic side</orientation>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="12">Endosome membrane</location>
            <topology evidence="12">Peripheral membrane protein</topology>
            <orientation evidence="12">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="12">The C2 domains have an essential, but non-catalytic function. They may facilitate interactions with other proteins and are required for lipid transport function.</text>
    </comment>
    <comment type="PTM">
        <text evidence="12">Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The autoendoproteolytic cleavage occurs by a canonical serine protease mechanism, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain. During this reaction, the Ser that is part of the protease active site of the proenzyme becomes the pyruvoyl prosthetic group, which constitutes an essential element of the active site of the mature decarboxylase.</text>
    </comment>
    <comment type="similarity">
        <text evidence="12">Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Eukaryotic type II sub-subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.1.1.65" evidence="12"/>
    <dbReference type="EMBL" id="LUGH01000104">
        <property type="protein sequence ID" value="OBZ89267.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NJG4"/>
    <dbReference type="FunCoup" id="A0A1C7NJG4">
        <property type="interactions" value="80"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NJG4"/>
    <dbReference type="InParanoid" id="A0A1C7NJG4"/>
    <dbReference type="OrthoDB" id="5973539at2759"/>
    <dbReference type="UniPathway" id="UPA00558">
        <property type="reaction ID" value="UER00616"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010008">
        <property type="term" value="C:endosome membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005795">
        <property type="term" value="C:Golgi stack"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004609">
        <property type="term" value="F:phosphatidylserine decarboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006646">
        <property type="term" value="P:phosphatidylethanolamine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016540">
        <property type="term" value="P:protein autoprocessing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00030">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.150">
        <property type="entry name" value="C2 domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00663">
        <property type="entry name" value="PS_decarb_PSD_B_type2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000008">
        <property type="entry name" value="C2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035892">
        <property type="entry name" value="C2_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003817">
        <property type="entry name" value="PS_Dcarbxylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033177">
        <property type="entry name" value="PSD-B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033179">
        <property type="entry name" value="PSD_type2_pro"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00163">
        <property type="entry name" value="PS_decarb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10067">
        <property type="entry name" value="PHOSPHATIDYLSERINE DECARBOXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10067:SF17">
        <property type="entry name" value="PHOSPHATIDYLSERINE DECARBOXYLASE PROENZYME 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00168">
        <property type="entry name" value="C2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02666">
        <property type="entry name" value="PS_Dcarbxylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00239">
        <property type="entry name" value="C2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49562">
        <property type="entry name" value="C2 domain (Calcium/lipid-binding domain, CaLB)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50004">
        <property type="entry name" value="C2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0106">Calcium</keyword>
    <keyword evidence="3 12" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="12" id="KW-0967">Endosome</keyword>
    <keyword evidence="12" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="2 12" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="5 12" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="9 12" id="KW-0456">Lyase</keyword>
    <keyword evidence="6 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="8 12" id="KW-0594">Phospholipid biosynthesis</keyword>
    <keyword evidence="10 12" id="KW-1208">Phospholipid metabolism</keyword>
    <keyword evidence="11 12" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 12" id="KW-0865">Zymogen</keyword>
    <feature type="chain" id="PRO_5023513299" description="Phosphatidylserine decarboxylase 2 beta chain" evidence="12">
        <location>
            <begin position="1"/>
            <end position="955"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5023513300" description="Phosphatidylserine decarboxylase 2 alpha chain" evidence="12">
        <location>
            <begin position="956"/>
            <end position="995"/>
        </location>
    </feature>
    <feature type="domain" description="C2" evidence="14">
        <location>
            <begin position="1"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="domain" description="C2" evidence="14">
        <location>
            <begin position="245"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="192"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="523"/>
            <end position="575"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="198"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="13">
        <location>
            <begin position="233"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="13">
        <location>
            <begin position="546"/>
            <end position="564"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system; for autoendoproteolytic cleavage activity" evidence="12">
        <location>
            <position position="813"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system; for autoendoproteolytic cleavage activity" evidence="12">
        <location>
            <position position="869"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system; for autoendoproteolytic cleavage activity" evidence="12">
        <location>
            <position position="956"/>
        </location>
    </feature>
    <feature type="active site" description="Schiff-base intermediate with substrate; via pyruvic acid; for decarboxylase activity" evidence="12">
        <location>
            <position position="956"/>
        </location>
    </feature>
    <feature type="site" description="Cleavage (non-hydrolytic); by autocatalysis" evidence="12">
        <location>
            <begin position="955"/>
            <end position="956"/>
        </location>
    </feature>
    <feature type="modified residue" description="Pyruvic acid (Ser); by autocatalysis" evidence="12">
        <location>
            <position position="956"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="OBZ89267.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="995" mass="113627" checksum="49FE490948CD2658" modified="2016-11-30" version="1">MTETKQELIFKVDIIEARSLSKDDEVIHPYAQVTYGGIKHKTDTIKKTQQPNWNCSFEFDLNDILSHKKRVRSLKDHGLTLSIYNKDRFTSVFLGQTRWSLEELFSGQSVAYEENSVEYQNKKYDRAKWHPLSHVRHHKRFRLRKRREDTSASEAEQAEVHVRYGLIGKHDQTAENIAAEWQNVLSMLSVQEVPSPPELQSSSSTSSANQESRIMVENSSTLSVSSTNTPKTTRPRRKLRSKFSRRGKSQKQAGYYSRFLSKVTGVTFLEIESANDLPPERNVTRTGFDMDPFVIVTYGVNTFRTSAIRHNLNPVWNEKLFFHVRSSQENYKIKFAVYDKDKFSSNDFVASQEIKLSDIVNKTLESAEKPVEPENMDGDHTPADEIDRNMARYSIPLTLARPDKWPELRPKLTIRAKFVPYVEIRKLFWTALAKTCDADSSNTMSKLEVQTMLETLGSNISECTINRFWKENNKDLSEDLTMDELVNSLEALMLDLDERQKRVDVNALIESGQDVPEEIANKKLSNPFFPGSSDDESVSEAVGSSDTEDDYDSDMGYDSAEYDESISTSPETPDEADYEVLAEADGVQYVDDSLESLRIHEDEKQHEHKDHNAHLAKEKLIHLTECPICHKTDLTKRMQMDTITHVAICAANDWTTVDQFLIGNFGSEAQAQRRWFVKLVSKVGYGKYSEGENNANIIVQDRSTGLLIDERMSVYVRLGMRLLYKGMKTGIHTKTAHRILANMSIKQGRRFDNPNSVREIAPFIKFHRLDLSEVLEPIENFKTFNEFFYRKLKPGSRPCDNPEDKRVAVSTADCRMMAFPTVDDATRIWIKGVEFSLAKLLDDEEEAKTFEGGALAIFRLAPQDYHRYHSPVDGTVRKIHHVKGEYYTVNPMAIRTTLDVYGDNKRDIVYMDTEVFGRVAIVCIGAMMVGSIVLTAKEGDYLARTDELGYFAFGGSTLVVLFEKDSIQFDNDLIDNANRSLETLVRVGNHIGVHP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NJK5</accession>
    <name>A0A1C7NJK5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="10">NAD-dependent protein deacetylase hst1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">A0J61_02946</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the sirtuin family. Class I subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000119">
        <property type="protein sequence ID" value="OBZ88999.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NJK5"/>
    <dbReference type="FunCoup" id="A0A1C7NJK5">
        <property type="interactions" value="288"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NJK5"/>
    <dbReference type="InParanoid" id="A0A1C7NJK5"/>
    <dbReference type="OrthoDB" id="420264at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046970">
        <property type="term" value="F:histone H4K16 deacetylase activity, NAD-dependent"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070403">
        <property type="term" value="F:NAD+ binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1600.10">
        <property type="entry name" value="SIR2/SIRT2 'Small Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1220">
        <property type="entry name" value="TPP-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029035">
        <property type="entry name" value="DHS-like_NAD/FAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050134">
        <property type="entry name" value="NAD-dep_sirtuin_deacylases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003000">
        <property type="entry name" value="Sirtuin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026591">
        <property type="entry name" value="Sirtuin_cat_small_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026590">
        <property type="entry name" value="Ssirtuin_cat_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11085:SF9">
        <property type="entry name" value="NAD-DEPENDENT PROTEIN DEACETYLASE SIRTUIN-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11085">
        <property type="entry name" value="NAD-DEPENDENT PROTEIN DEACYLASE SIRTUIN-5, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02146">
        <property type="entry name" value="SIR2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52467">
        <property type="entry name" value="DHS-like NAD/FAD-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50305">
        <property type="entry name" value="SIRTUIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0520">NAD</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="5 7" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Deacetylase sirtuin-type" evidence="9">
        <location>
            <begin position="195"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="362"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="487"/>
            <end position="511"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="545"/>
            <end position="579"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="14"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="31"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="61"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="492"/>
            <end position="511"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="562"/>
            <end position="572"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="7">
        <location>
            <position position="320"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="328"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="331"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="352"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="355"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006924"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50305"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OBZ88999.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="579" mass="65168" checksum="588298E3EAD2509B" modified="2016-11-30" version="1">MSDEDENQHREGLSSGNKRFSSEHNSVQEEEQIKKARLDDQSEETQPDPAVTASLSINDALFDDYNEESDQDWASGDESESSLSDQGILSHPAFQVDGDSLDDVDIDGSDEESRYQLSWTSFSEEEMEAIREEAREKGLIKFIEKYIVQESVPVPKMLEAFDIFMHPKAAALASDIELLPILRSVVTRCLRKRRRLENVNTLEDVADLLSKANNIMIVTGAGVSVSCGIPDFRSEKGIYSRLQEYELDDPQQMFDIEYFREMPEIFYTFAKELYPANYEPSPGHMFVKLIEEKGKLLRNYTQNIDTLEHKANIKRVVNCHGSFATASCVTCGYKVDGKEIEEYIMAQKVAPCPQCQAIKASLPDKSRKDGSDDDDDDAVPSPRGVSIMKPDITFFGERLPAEFDNLLAVDTDQVDLLIVMGSSLKVSPVSEIMSQIPHSIPQILINRTPITHMTFDIQLLGDSDAIVPELCRMLNWDLKHPKLPGGSALSEESMRLSREGSGDLVQTKDESGQIRSERKIWSFVRDGLYTFPGAVVDPKYMNNQRCDERGCINSSDSEDEQETKSTTEKETSEVNPQED</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NJS7</accession>
    <name>A0A1C7NJS7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">A0J61_02558</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000098">
        <property type="protein sequence ID" value="OBZ89381.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NJS7"/>
    <dbReference type="FunCoup" id="A0A1C7NJS7">
        <property type="interactions" value="96"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NJS7"/>
    <dbReference type="InParanoid" id="A0A1C7NJS7"/>
    <dbReference type="OrthoDB" id="2985014at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000013">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000057">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791">
        <property type="entry name" value="PERMEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791:SF36">
        <property type="entry name" value="TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_6G08340)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="156"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="190"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="260"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="293"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="323"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="347"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="382"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="413"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="24"/>
            <end position="440"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OBZ89381.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="472" mass="52514" checksum="AD68548512628FF1" modified="2016-11-30" version="1">MATSVTKSNSSLSMLSADQPMDEQTFQVTEKRLVRKLDLRLIPWLSVLYLMLSLDRNNIGNARLGSLEKDLNLVGNEYYTALTIFFAVVKRFSPSRWMAGTMVLWGICSLCQAFTHNAAGLIVCRFFLGCFEVGVGPSTPLYLSFWYQRKELATRVAIYFGSSTIAGAFAGAIAYGVLSNLDGAHGVAGWRWLFIVEAIPTIVLGIMSFIVLPDLPETANRWLTAEEKRVALQRTRQSGNTDAVFFDKQQFFAALMDYKVWLAVIIYVGLNIALSSFAIFLPTIIRDMGFSSLHAQLLSIPPYVVACCLLVSWNSDRTLQRGYHIIGVCSLGILGYIFLLATDQIGVRYTGAILVACGIYPIIPLTLSWVSNNQLGHTKRGVAIAMTSMIAQCFSMLGTQIYRTEDGPRYIKGHVICLIFLGLAACSAGLLRFLLARENTRRNKEFGAPSEDMTHIDFIGLYDRHPSFRYTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NJT0</accession>
    <name>A0A1C7NJT0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">ATP-dependent DNA helicase</fullName>
            <ecNumber evidence="1">5.6.2.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_02534</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="5.6.2.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the helicase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.6.2.3" evidence="1"/>
    <dbReference type="EMBL" id="LUGH01000097">
        <property type="protein sequence ID" value="OBZ89403.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NJT0"/>
    <dbReference type="STRING" id="101091.A0A1C7NJT0"/>
    <dbReference type="InParanoid" id="A0A1C7NJT0"/>
    <dbReference type="OrthoDB" id="1075553at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043139">
        <property type="term" value="F:5'-3' DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000723">
        <property type="term" value="P:telomere maintenance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010285">
        <property type="entry name" value="DNA_helicase_pif1-like_DEAD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10492">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05970">
        <property type="entry name" value="PIF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0227">DNA damage</keyword>
    <keyword evidence="1" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="1" id="KW-0234">DNA repair</keyword>
    <keyword evidence="1" id="KW-0347">Helicase</keyword>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA helicase Pif1-like DEAD-box helicase" evidence="2">
        <location>
            <begin position="326"/>
            <end position="425"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU363044"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF05970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ89403.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="427" mass="48727" checksum="D6BB254C8B25CCC1" modified="2016-11-30" version="1">MKSVYLTNQNVVPYNPFLTKKYKAHINIELCGSADAIKCINKCVYKGPDRTTIHLRNENDEIERYLTSRYIGPTEAVWRLFEYVMHEEDPSVTSLSVHLENGQPIYFDPEASAEEIQLILDNMHSALMGFFKYNAANENGRRMYYCTPTAGERFFLRLFLTVVRGPTSFQDLRTVKGVVYATFREACQALHLIEDDQDLCSLLISALLFQELNQPAALWNEFCLSICDDLDVRMRQLGFADQLNSHETEHAFHKDLPKLDYGLYLLEQALIDAGKTLADFNMPQPLFDWRHLMEQIGEISSNAVFQTGVAYDRNIEEAKYQQKVSMMNTGQKVAFDEIIDNIFSNPKTAHFFLQGPAGTGKTLVYNTLCHYFRRQRRVVVRIASSGIASLLLPGGRTSHSRFKIPLNIFPDSVCLIKKDSDLASIVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NJX1</accession>
    <name>A0A1C7NJX1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">SET domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_02470</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000094">
        <property type="protein sequence ID" value="OBZ89462.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NJX1"/>
    <dbReference type="STRING" id="101091.A0A1C7NJX1"/>
    <dbReference type="InParanoid" id="A0A1C7NJX1"/>
    <dbReference type="OrthoDB" id="5792673at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.270.10">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001214">
        <property type="entry name" value="SET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046341">
        <property type="entry name" value="SET_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00856">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00317">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82199">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50280">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SET" evidence="1">
        <location>
            <begin position="75"/>
            <end position="196"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ89462.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="214" mass="24472" checksum="AA885DB63E677682" modified="2016-11-30" version="1">MNYLKDIKTVTPPSGWTPETKYIDKLFWSPNVPADQKELFQPTNPNKEDPRRTINFMNQHVNLVGTFPGIKEQKRHVKIKKITDPNHPCCGAYGLFAAQTLQPKQLIIDYLGVVEYQDGYEATSDYVLKYSVDLSIDAGRCGNEARFCNDFRGCGPEPNVCFMNYMDEKTKHIKVAIFVNGNRKIKKGDELLVTYGKSFWAKRGIDMSGQKHKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NK49</accession>
    <name>A0A1C7NK49_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Adenylate cyclase type 10</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">ADCY10</name>
        <name evidence="5" type="ORF">A0J61_02575</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000098">
        <property type="protein sequence ID" value="OBZ89378.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NK49"/>
    <dbReference type="InParanoid" id="A0A1C7NK49"/>
    <dbReference type="OrthoDB" id="194468at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004016">
        <property type="term" value="F:adenylate cyclase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009190">
        <property type="term" value="P:cyclic nucleotide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035556">
        <property type="term" value="P:intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1230">
        <property type="entry name" value="Nucleotide cyclase"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001054">
        <property type="entry name" value="A/G_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041664">
        <property type="entry name" value="AAA_16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16305:SF28">
        <property type="entry name" value="GUANYLATE CYCLASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16305">
        <property type="entry name" value="TESTICULAR SOLUBLE ADENYLYL CYCLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13191">
        <property type="entry name" value="AAA_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="Nucleotide cyclase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50125">
        <property type="entry name" value="GUANYLATE_CYCLASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="1535"/>
            <end position="1557"/>
        </location>
    </feature>
    <feature type="domain" description="Guanylate cyclase" evidence="4">
        <location>
            <begin position="33"/>
            <end position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OBZ89378.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="1703" mass="194600" checksum="4D145E362DC3B2C2" modified="2016-11-30" version="1">MLNIAPYIAKYVRSLHAHKEQLKLPYIQSQFGVVLMVDVVGFSALTTKAAEKGGSGAEAIALEIGTYMGECIEIIEHFGGDVVKFLGDAVLVSFQTIDCEEEEQDMTESNISVKEREARHKKLLVKKAVECGLQLLSRLSHYRVYLTAEERSRHRSNTATEMEHRFNPNIANASNERFLLFDGGGTASESERTLSRDSFQNMSSLFDYDYGYHEEYSTSFNFWNCIPMLFGKGSSRKKNRVYASMRRRSHTSDTTNGEPDAIDLELHIGLSCGDITNVVLGDMKSSVSNIKKKRKSQTRVTTTDEQATLDYAGRLEYAICGPAVESLEDALTVAKAGEMSITAEAYNIFQSQHISLSCEKRNQFYVAKSSDTITYSHSNTNNKKRSFTAHYRSSSAYNTNYFSDHPGLTKRSTAPTMTPMHSDSRVESVVSIPPDSNPNYFKYINQSALYRLQHSPDGNFLPQFRDVTIMFISLGKLNVATPEGARIAQRATVATIRALLRYEGVLQQFAVDDKGATLLAVFGLPPLSHEREAIFAAKAAIDLRDNFMGFLDDFAISLSTGVIFNAVLPQDNPYRRDPGIAGDTIILAVRMLKFPFSKKNIVCDFATKQQIGRICDFEEYGENFVKGKVKPILIYGILRFAVSKNKRISTQSQEKNSDFIGYKAEMSLATRCVDDWMESSNHHLLVVSGPSGVGKSFFCHALSRNIISNGAICCWSSCTEVEKSSKYYLVKNILLSLFEIIDSDQVPQNTRRRVPYLSGSGGFYLADSVQSHQSNPEVASIISSSSSVCPSPTTTKDNYSHTHRQLFDHAQRLRSYSTISRFSSNNEPRERIEGFNELEDLIIRCLRICGEEDGFLPLFKVVFSVLTDMEDNRYTRRLDGRARDVLLTSLISRMTRYVSEHVGLVFILDDVQWADSASIRLLQHIHEHCQRVMLILATRPVKDYNVTFVNDFRETGHSKEIELNGLGAAEIGEIILQTFQTANVKEVSPKIVRVIQERTAGNPLYVKNMAIVLKDFNHVTVVENTLVPTSTRFDLEDLLGNFDYKRIIKMQFDRLEGSFQEFLTVASCLDQYFTIQEVQAVIKEYNMDFKYATDEEARQKIELYDVYHFLQKTDDSLLSSELYTFTHITIPQSIYDMASYETRIMLHRLLAKYYESLLTRENYTELLGKVTRHYLQTEWLDKQLYYLEALADINMKAFLLPEATTNLERIVKILDSNQDLEAQFGRIHRSDIYRRLGMCFTMRTKLKEGEKYLHQALVCLGEPWPQSDPEFLFKFWVNRIAQYRHRKLRVFRKVDKDLKKEIAKRVVEIMAQLSSIYFYTGKGRFFVYTCLVGLNACERLDEVGPNYTLFLARNSLLSWLNDEKQQSIFYITKALRYMDQKNDADTLTICSFLCFAAGKFKNARDLLYQSIEAVKTLGVITDCQAFYRSVGLIITMRIFEGTLDNSPDDLVLLKQMADTAHSNCDFEAEIWLSVYNVGNALIKDRLRDCEPFVALLEAHLKQSEDFNRIAIHGTLLCYYARTRNYEYARRHTRNLVAVLPLLTVTPNIFPIFGLIFATMGMYCMIEDSQVDFVNTGDAKNYDRFILGVSRINHAFQQVKFWEFTQPCLYLARALPYISTGRTVEGFMVLQHGVLEMRFIQEIRFLKAFYWANLGKYAFTPADRIEWTHRAKVDFEELKIPSHVYCNPDPENSYSRHSPADLTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NKE2</accession>
    <name>A0A1C7NKE2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">protein-serine/threonine phosphatase</fullName>
            <ecNumber evidence="2">3.1.3.16</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">CPL4</name>
        <name evidence="9" type="ORF">A0J61_02353</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>O-phospho-L-seryl-[protein] + H2O = L-seryl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:20629"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="EC" id="3.1.3.16"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:47004"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="EC" id="3.1.3.16"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.16" evidence="2"/>
    <dbReference type="EMBL" id="LUGH01000087">
        <property type="protein sequence ID" value="OBZ89601.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NKE2"/>
    <dbReference type="STRING" id="101091.A0A1C7NKE2"/>
    <dbReference type="InParanoid" id="A0A1C7NKE2"/>
    <dbReference type="OrthoDB" id="10249888at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008420">
        <property type="term" value="F:RNA polymerase II CTD heptapeptide repeat phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039189">
        <property type="entry name" value="Fcp1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004274">
        <property type="entry name" value="FCP1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23081">
        <property type="entry name" value="RNA POLYMERASE II CTD PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23081:SF36">
        <property type="entry name" value="RNA POLYMERASE II SUBUNIT A C-TERMINAL DOMAIN PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03031">
        <property type="entry name" value="NIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00577">
        <property type="entry name" value="CPDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50969">
        <property type="entry name" value="FCP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FCP1 homology" evidence="8">
        <location>
            <begin position="326"/>
            <end position="511"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="99"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="135"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="30"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="50"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="111"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="151"/>
            <end position="162"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013081"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00047761"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00048336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50969"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OBZ89601.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="576" mass="65779" checksum="8BBDA2B80963D5BA" modified="2016-11-30" version="1">MDLSSMLNDAVPAPKAPVITNNKRAHNDNMKSTVNEKNTQSREFNYHPHPSNTSSAATTPQPSNNNNNNHIDHMPSKGKAMVYQLATSVHYLVSKDPSVNRTHMLTPPPRSNTTTPPLTSTVSGRPIANLLSSPFRPPSEHNSPRMSVLHTSVPSPSGSSATSNLLRLGPALRNDPSLWKTKLSLRLVINEQPVSLRPSKRPKVNRLEDNLETPLKIHEIIIRGDEPKVLLEDVYEIQGAYPRGFFVLMAKRNIMHNFVFAYPDHPWFEDLYGLRKSAYICMRTEEGELYELHLKPSRDKMFLFGYLIKHIDMIRIVKDSMTEIVYQQRRLPLVLDLDDTLVRLVGEGNERYVPEAELSKCRDRVATLKDGRRVVLADRVHDFLEWAQNLYDISVCSLGDQNYVENVVEVLDPNRTRIRGILYSARMEHDYIKKSPDPGRPPKDLLALYSFCALKDRSFGSAFSLPLILDDETRMWPLEQQDNIIEVMSQRNAPVWTVSLFPVVKDTLEFIHAQFFRQFDMWNAKCQEAEQVGTVYTRPPPSAVAIYKAHLRSLMRDMIAKGPLIYSANNQQNNHH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NL85</accession>
    <name>A0A1C7NL85_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">CBS domain-containing protein CBSCBSPB3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">A0J61_03879</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000177">
        <property type="protein sequence ID" value="OBZ88064.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NL85"/>
    <dbReference type="FunCoup" id="A0A1C7NL85">
        <property type="interactions" value="10"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NL85"/>
    <dbReference type="InParanoid" id="A0A1C7NL85"/>
    <dbReference type="OrthoDB" id="418595at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd17781">
        <property type="entry name" value="CBS_pair_MUG70_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd17782">
        <property type="entry name" value="CBS_pair_MUG70_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.580.10">
        <property type="entry name" value="CBS-domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000644">
        <property type="entry name" value="CBS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046342">
        <property type="entry name" value="CBS_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051462">
        <property type="entry name" value="CBS_domain-containing"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053793">
        <property type="entry name" value="PB1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000270">
        <property type="entry name" value="PB1_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48108">
        <property type="entry name" value="CBS DOMAIN-CONTAINING PROTEIN CBSX2, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48108:SF26">
        <property type="entry name" value="CBS DOMAIN-CONTAINING PROTEIN DDB_G0289609"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00571">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00564">
        <property type="entry name" value="PB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00116">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00666">
        <property type="entry name" value="PB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54277">
        <property type="entry name" value="CAD &amp; PB1 domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54631">
        <property type="entry name" value="CBS-domain pair"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51371">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51745">
        <property type="entry name" value="PB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0129">CBS domain</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="624"/>
            <end position="643"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="5">
        <location>
            <begin position="69"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="5">
        <location>
            <begin position="136"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="5">
        <location>
            <begin position="307"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="domain" description="PB1" evidence="6">
        <location>
            <begin position="460"/>
            <end position="549"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="585"/>
            <end position="614"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="30"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="48"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="585"/>
            <end position="596"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="603"/>
            <end position="614"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51745"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OBZ88064.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="648" mass="72016" checksum="924D9D734573CC75" modified="2016-11-30" version="1">MSTVKKNTPKKLRAIETHDQADSSGRQRQQKRDEAIRKKLEQDFSKKGSSKSSRKSQKYNRIPGTVSALRPGQALTVKENMLVLEASQLMAAKRCDCVLVVNENDHLSGIFTAKDIAYRLVAEDLKAKKTLVIDIMTKNPVCVTSDTSATEALNLMVTRGFRHLPVCNEEGDIFGLLDITKCLYGALEKIERTFETSQANYNNSVLEGMQREWGNVPPAQLAEYMETLREQMSCPNLQSLLDGTPPAEVKYKTNVRDIAVMMKQLRTTAVLVTRHRSLAGIFTSKDIVLRVIAAGLDPEICTVARVMTPNPDTATPETSVLDALKLMNEGHYLNLPVLENGTITGMVDVLKLTYVTLEQMSNIEGERDGAGHDGPMWGRFWDSFGATDITDSASQLSDTTSSYLVPNKGSSGGSQLYPYPNISPQPSTSLSHLKSFPDISPNESASMVNQTEVSSVTHSTFTFKFTSQNNKTHRVVCQPAFSILLEAVRAKLLPEHGEGDVGEEEWLTLSYVDDEDDTVLISCDADVIDAVHLARKEGQSRVKLIVHDSHLNTTPTHLETTIIEEKEELEEPVAQRTVLAREVVHEEEKQEEKVEEKEEEKEEEKPVKKSKRAHEAAVHVPNELLLPAAITFLGVVILGVFVFSRKQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NLD2</accession>
    <name>A0A1C7NLD2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Transcription factor LBX2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">LBX2</name>
        <name evidence="9" type="ORF">A0J61_02027</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 5 6">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000072">
        <property type="protein sequence ID" value="OBZ89922.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NLD2"/>
    <dbReference type="STRING" id="101091.A0A1C7NLD2"/>
    <dbReference type="InParanoid" id="A0A1C7NLD2"/>
    <dbReference type="OrthoDB" id="6159439at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030154">
        <property type="term" value="P:cell differentiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00086">
        <property type="entry name" value="homeodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001356">
        <property type="entry name" value="HD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051000">
        <property type="entry name" value="Homeobox_DNA-bind_prot"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24324:SF5">
        <property type="entry name" value="HEMATOPOIETICALLY-EXPRESSED HOMEOBOX PROTEIN HHEX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24324">
        <property type="entry name" value="HOMEOBOX PROTEIN HHEX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00046">
        <property type="entry name" value="Homeodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00389">
        <property type="entry name" value="HOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50071">
        <property type="entry name" value="HOMEOBOX_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 5 6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3 5 6" id="KW-0371">Homeobox</keyword>
    <keyword evidence="4 5 6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Homeobox" evidence="8">
        <location>
            <begin position="29"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="Homeobox" evidence="5">
        <location>
            <begin position="31"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OBZ89922.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="204" mass="23929" checksum="0FE209840C7E0DA4" modified="2016-11-30" version="1">MPSNKRKATRKRKTVEESEDNWSDDYIYPSSIKRRRRFSVQETNKLEEEYSFNASPSQERLQQIANEIGTARKIVTTWFQNRRAKHKRNEKKEEAVMNDGEIGLTRDVRYDVPQIHYINQIVDACRPPETSTNNPEYTMVDSSVMYPPCMNTLQSHVMLNLAESDSWIPTDEAQEEHFMLPYSIETNDGSLYINPSQLLLNYQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NLZ1</accession>
    <name>A0A1C7NLZ1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">PHD finger protein 14</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">Phf14</name>
        <name evidence="7" type="ORF">A0J61_01956</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000068">
        <property type="protein sequence ID" value="OBZ90010.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NLZ1"/>
    <dbReference type="STRING" id="101091.A0A1C7NLZ1"/>
    <dbReference type="InParanoid" id="A0A1C7NLZ1"/>
    <dbReference type="OrthoDB" id="2209589at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048189">
        <property type="term" value="C:Lid2 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004842">
        <property type="term" value="F:ubiquitin-protein transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036205">
        <property type="term" value="P:histone catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029617">
        <property type="entry name" value="Snt2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001965">
        <property type="entry name" value="Znf_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019787">
        <property type="entry name" value="Znf_PHD-finger"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47672">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE SNT2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47672:SF1">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE SNT2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00249">
        <property type="entry name" value="PHD"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50016">
        <property type="entry name" value="ZF_PHD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="PHD-type" evidence="6">
        <location>
            <begin position="114"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="26"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="442"/>
            <end position="539"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="442"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="468"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="479"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="501"/>
            <end position="528"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OBZ90010.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="657" mass="74354" checksum="C895DAE6C21BD258" modified="2016-11-30" version="1">MSYTGRGAPLNWDSTSSTLLMPLELTPSQLPTTASNQSQSFIENGSSSAPSQSTTAKPLLLMPSESPSAKSPEIVTHTSNVDPQKYAVPDRSTSFEKIKNLGRFVYTWRFRHAPSACCICFDDNSAEPIESCDNLLCDVRLHSSCYQKIKKTTRARIHRRWLCDKCTYLESSSLTVVCALCPSTAGLFCMINPNHYSIFWVHYNCAKAFLGEEAIVYKPDLGHFDIKIDSISLVNFEQPCSDCAKSSYSRYGAKIVCRICRTYHHITCIEQYNLKIPDEPYECPDHGSARPRGSEILRRRRLATSYHRWIGKKNHFLLEEFKKVPRMFGLDYWKSLNLDTLSMGDVTEWYKKSVYIIQTNETYPVANTYYNQWVDYVLSLAMSAYSSYEIGNSKLMFTTKHFDEDIGYDFKIPDGAIISESGESSSAQRLAEQTFMTQLTAIQPENTQSDKIQPQKTQPKRIQPKNAQSESTQSEQTQPTKTGTESAQLSTTDPTVKEPVATRSTIARSAATRTSSRQSSPSSNTSVSRKSRNTHLPPAVTPSDDLICAICLQHDLSEAVWERHGLDSEYKENLERTKHKRQPGFTGSGNNWDPRVFIQCCKCDVTVHCGCPVPPIKSYPQRFRVFICIRCDTKQDETTIEQEPTGVRRTNVVNYKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NM88</accession>
    <name>A0A1C7NM88_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Protein KES1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">KES1_1</name>
        <name evidence="3" type="ORF">A0J61_01740</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the OSBP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000059">
        <property type="protein sequence ID" value="OBZ90195.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NM88"/>
    <dbReference type="FunCoup" id="A0A1C7NM88">
        <property type="interactions" value="75"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NM88"/>
    <dbReference type="InParanoid" id="A0A1C7NM88"/>
    <dbReference type="OrthoDB" id="14833at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008142">
        <property type="term" value="F:oxysterol binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.2720">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.160.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.3490">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.1430">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037239">
        <property type="entry name" value="OSBP_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000648">
        <property type="entry name" value="Oxysterol-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018494">
        <property type="entry name" value="Oxysterol-bd_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10972:SF184">
        <property type="entry name" value="OXYSTEROL-BINDING PROTEIN HOMOLOG 4-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10972">
        <property type="entry name" value="OXYSTEROL-BINDING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01237">
        <property type="entry name" value="Oxysterol_BP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144000">
        <property type="entry name" value="Oxysterol-binding protein-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01013">
        <property type="entry name" value="OSBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003844"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ90195.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="391" mass="44401" checksum="89261DEA66B4D6BB" modified="2016-11-30" version="1">MSNTDNEVNNVDQIPQEQKGAFHSFLKSLASFSGDLSSLTCPAFLLAPVSLIEYSEYWTQQPDLFTDIAKSDDEVERMVAFVKWFISSLNASYSRRVPKGEWEKKPYNPVLGEQFKMTWGDLNGTGNTDVLVEQVSHHPPVTGFYIKNDKAGISLNGHTGQKTRFSSTSLIVDQVGQSLVTLKNRDNEQYLFSYPSITVNGIWYAAPYIELLGTSYIQSSTGLYCSIEYTSRGWISGTRNYFKCYIRRNSGGNSKEYLYKIEGQWSGKSTITKYGSKTAEPFLDVTELTPAPMHVKEIEEQDEMESRRIWQKVSEAIRANDTNLAGVEKAKIENQKREEKAARQAAGTEWEPHYFHWVPEEPTVSALQRMLTSTVKNKYTPATNGNWVYKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NMF6</accession>
    <name>A0A1C7NMF6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">FAR1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_01681</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000056">
        <property type="protein sequence ID" value="OBZ90277.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NMF6"/>
    <dbReference type="InParanoid" id="A0A1C7NMF6"/>
    <dbReference type="OrthoDB" id="2276242at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010106">
        <property type="term" value="P:cellular response to iron ion starvation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014842">
        <property type="entry name" value="AFT"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08731">
        <property type="entry name" value="AFT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ90277.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="200" mass="23299" checksum="F766953236650B51" modified="2016-11-30" version="1">MASFIFYEQMTVNETEHHPDLHAVVEPFPQMTTGMTRESLDGLMTEYATRNNFVMVVDKSDAKRLVLQCEKGGHYKHKKLGARKRQPRSSHKINCPYRIRFSKLKNDKGFKVNKPVNQTELLHNHPLDFHNLISTNRGRKNHGLFTEVKLEPKLDVAPSWKDTVARLEATFYRYREDPEKMQSLMNAIESILHDYTPSAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NMJ6</accession>
    <name>A0A1C7NMJ6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">histidinol-phosphate transaminase</fullName>
            <ecNumber evidence="4">2.6.1.9</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Imidazole acetol-phosphate transaminase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="primary">his3</name>
        <name evidence="13" type="ORF">A0J61_01700</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>L-histidinol phosphate + 2-oxoglutarate = 3-(imidazol-4-yl)-2-oxopropyl phosphate + L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:23744"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:57766"/>
            <dbReference type="ChEBI" id="CHEBI:57980"/>
            <dbReference type="EC" id="2.6.1.9"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Amino-acid biosynthesis; L-histidine biosynthesis; L-histidine from 5-phospho-alpha-D-ribose 1-diphosphate: step 7/9.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.6.1.9" evidence="4"/>
    <dbReference type="EMBL" id="LUGH01000057">
        <property type="protein sequence ID" value="OBZ90238.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NMJ6"/>
    <dbReference type="FunCoup" id="A0A1C7NMJ6">
        <property type="interactions" value="134"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NMJ6"/>
    <dbReference type="InParanoid" id="A0A1C7NMJ6"/>
    <dbReference type="OrthoDB" id="2015537at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004400">
        <property type="term" value="F:histidinol-phosphate transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000105">
        <property type="term" value="P:L-histidine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00609">
        <property type="entry name" value="AAT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01023">
        <property type="entry name" value="HisC_aminotrans_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001917">
        <property type="entry name" value="Aminotrans_II_pyridoxalP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004839">
        <property type="entry name" value="Aminotransferase_I/II_large"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005861">
        <property type="entry name" value="HisP_aminotrans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01141">
        <property type="entry name" value="hisC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42885:SF2">
        <property type="entry name" value="HISTIDINOL-PHOSPHATE AMINOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42885">
        <property type="entry name" value="HISTIDINOL-PHOSPHATE AMINOTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00155">
        <property type="entry name" value="Aminotran_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00599">
        <property type="entry name" value="AA_TRANSFER_CLASS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="5 13" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="9" id="KW-0368">Histidine biosynthesis</keyword>
    <keyword evidence="8" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 13" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotransferase class I/classII large" evidence="12">
        <location>
            <begin position="31"/>
            <end position="365"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008392"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012748"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00030262"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00047481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF00155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="OBZ90238.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="378" mass="41919" checksum="DD72DD97D054F3D4" modified="2016-11-30" version="1">MPFDLTRVIRPNILALKPYRCARDDFSEGVLLDANENAYGPALKTEQKGDLNRYPDPYQVQVKERLLKLRNLKSVRNLFLGVGSDEVIDLLIRVACVPTKDKILITPPTYGMYSVCAQINDVEVIKSPLNVENGAYQLDLDHVFTTIKSNPDIKLIFLCSPGNPTGTCLSHASIRAVLESDYEGIVVVDEAYVDFVDKEEGSVANWVDQYPNLVVMQTLSKSFGLAGIRVGIAVGHADLIQILNNTKAPYNIGTPSALLAAEALSEEGIQKMLEYRQRLIAQRGLMIERLNGMQEMGRILGGNDANFVLVEVLDKATQKPSNDRAHKIYLMMAESLGVVVRFRGTEYGCDSCLRITVGTEEENEKMFVMLEKALEATA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NMT6</accession>
    <name>A0A1C7NMT6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein YbeQ</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">ybeQ_2</name>
        <name evidence="2" type="ORF">A0J61_01512</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the sel-1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000049">
        <property type="protein sequence ID" value="OBZ90443.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NMT6"/>
    <dbReference type="STRING" id="101091.A0A1C7NMT6"/>
    <dbReference type="InParanoid" id="A0A1C7NMT6"/>
    <dbReference type="OrthoDB" id="2260164at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006597">
        <property type="entry name" value="Sel1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050767">
        <property type="entry name" value="Sel1_AlgK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11102:SF160">
        <property type="entry name" value="ERAD-ASSOCIATED E3 UBIQUITIN-PROTEIN LIGASE COMPONENT HRD3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11102">
        <property type="entry name" value="SEL-1-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08238">
        <property type="entry name" value="Sel1"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SMART" id="SM00671">
        <property type="entry name" value="SEL1"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81901">
        <property type="entry name" value="HCP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00038101"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ90443.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="359" mass="41212" checksum="5344FDA4E4AE63DD" modified="2016-11-30" version="1">MKRLISIIKEDAFIKKKETSTKLDQLYQTGLNYYKASEYENAFIFLSLAAEHEHKIAQYVLGVMYGKGKGVTQDFAKAVAWYRKSALNGHPKAHYNLGVCYRDGIGVPKDWSKALYWFTLAAENGDVDSQYSTAIIYYKGDPQDHKMAYLWFKAAAENDHVMARYALGTLFFHGHGVSRDLKKALVWFERASDLESSGDAYYHVGLIQEMFSRYEEAIAAYVKGSDKGSSEAELHLGRLYETFYQNNTKAVYWYAKSAIHGNRYAQTYLTQLYMRHGPSQDFKLALEWLEQHHEADNTNFSQPLYDLQKLMASVYNENIFQASFPTIDQLKTNRVDTFVKKCNMTNNSDLSDEGNDLAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NMW6</accession>
    <name>A0A1C7NMW6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Eukaryotic translation initiation factor 3 subunit G</fullName>
            <shortName evidence="5">eIF3g</shortName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Eukaryotic translation initiation factor 3 RNA-binding subunit</fullName>
            <shortName evidence="5">eIF-3 RNA-binding subunit</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="5">Translation initiation factor eIF3 p33 subunit homolog</fullName>
            <shortName evidence="5">eIF3 p33 homolog</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">tif35</name>
        <name evidence="5" type="synonym">TIF35</name>
        <name evidence="9" type="ORF">A0J61_01586</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. This subunit can bind 18S rRNA.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Component of the eukaryotic translation initiation factor 3 (eIF-3) complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the eIF-3 subunit G family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000052">
        <property type="protein sequence ID" value="OBZ90358.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NMW6"/>
    <dbReference type="FunCoup" id="A0A1C7NMW6">
        <property type="interactions" value="676"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NMW6"/>
    <dbReference type="InParanoid" id="A0A1C7NMW6"/>
    <dbReference type="OrthoDB" id="639027at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016282">
        <property type="term" value="C:eukaryotic 43S preinitiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033290">
        <property type="term" value="C:eukaryotic 48S preinitiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071540">
        <property type="term" value="C:eukaryotic translation initiation factor 3 complex, eIF3e"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071541">
        <property type="term" value="C:eukaryotic translation initiation factor 3 complex, eIF3m"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043614">
        <property type="term" value="C:multi-eIF complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001732">
        <property type="term" value="P:formation of cytoplasmic translation initiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002188">
        <property type="term" value="P:translation reinitiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006415">
        <property type="term" value="P:translational termination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd12933">
        <property type="entry name" value="eIF3G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd12408">
        <property type="entry name" value="RRM_eIF3G_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03006">
        <property type="entry name" value="eIF3g"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017334">
        <property type="entry name" value="eIF3_g"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024675">
        <property type="entry name" value="eIF3g_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034240">
        <property type="entry name" value="eIF3G_RRM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10352">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12353">
        <property type="entry name" value="eIF3g"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037949">
        <property type="entry name" value="Transl_init_eIF-3_RNA-bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 5 9" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="4 5" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="8">
        <location>
            <begin position="228"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="177"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="180"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="201"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="218"/>
            <end position="228"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OBZ90358.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="307" mass="33492" checksum="6B4E28B4197FC5E2" modified="2016-11-30" version="1">MAVDTTMPGKASWADEYDEEESFQPQVYTDEDGNKVIIEYRENDDGKKVKVTRKIRAKLVTEHVNKAVAERKKWAKFGEEAGKKAGPDLSTTTIGENIPLKLGSTTGKSAEAVAEEEAKNKIKAQAKTKNIACRICKGEHFTSKCPYKDTMQPMDEIASTIEAVKLDSLDAAAAAAASPSLESVSGSGPTKYTPPHLRNKAAGGAPATNGGAPTGESMRSEQKRDDSATLRVTNLSEDVTDNDIYDLFSRFGSIARVYLARDRETNLCKGFAFVSFSEREQAERAQQAINGYGYDNLILRVEFARSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NN40</accession>
    <name>A0A1C7NN40_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Palmitoyltransferase</fullName>
            <ecNumber evidence="10">2.3.1.225</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">PFA4_0</name>
        <name evidence="13" type="ORF">A0J61_03266</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9 10">
            <text>L-cysteinyl-[protein] + hexadecanoyl-CoA = S-hexadecanoyl-L-cysteinyl-[protein] + CoA</text>
            <dbReference type="Rhea" id="RHEA:36683"/>
            <dbReference type="Rhea" id="RHEA-COMP:10131"/>
            <dbReference type="Rhea" id="RHEA-COMP:11032"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57379"/>
            <dbReference type="ChEBI" id="CHEBI:74151"/>
            <dbReference type="EC" id="2.3.1.225"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="10">The DHHC domain is required for palmitoyltransferase activity.</text>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the DHHC palmitoyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.225" evidence="10"/>
    <dbReference type="EMBL" id="LUGH01000137">
        <property type="protein sequence ID" value="OBZ88684.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NN40"/>
    <dbReference type="STRING" id="101091.A0A1C7NN40"/>
    <dbReference type="InParanoid" id="A0A1C7NN40"/>
    <dbReference type="OrthoDB" id="331948at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019706">
        <property type="term" value="F:protein-cysteine S-palmitoyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001594">
        <property type="entry name" value="Palmitoyltrfase_DHHC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039859">
        <property type="entry name" value="PFA4/ZDH16/20/ERF2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011332">
        <property type="entry name" value="Ribosomal_zn-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12246">
        <property type="entry name" value="PALMITOYLTRANSFERASE ZDHHC16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01529">
        <property type="entry name" value="DHHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57829">
        <property type="entry name" value="Zn-binding ribosomal proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50216">
        <property type="entry name" value="DHHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 10" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="7" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="5 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0564">Palmitate</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 10 13" id="KW-0808">Transferase</keyword>
    <keyword evidence="3 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="12"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="48"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="144"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="184"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="domain" description="Palmitoyltransferase DHHC" evidence="12">
        <location>
            <begin position="99"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="296"/>
            <end position="317"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00048048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU079119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF01529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="OBZ88684.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="359" mass="41450" checksum="01939217BF3E33F5" modified="2016-11-30" version="1">MDVLESIPEQIVVAFVVCLISYLQLTTNFYVLGPALGGWFSLEAQKTLVPMNILLVSLYVNYYFACTTSPGYTPEGWEPPYAILNPSEDSVIQTGLTGPRFCKKCDAYKPPRAHHCRQCGRCVLRMDHHCPWIANCVGFGNYSYFVRFVFSVILCCSYGGYLLFWRLQRIFEARYNPWIPDPSLIEMGIIMMNLIFLFFIIMLVGVLAVYHSYCLLKGQTTIEGSERTKTKRLIRLRKIDPVEFPFDIGYCQNICSVLGSNPLFWMWPQGTPGNGLQYPTRPDTDPMVVYSWPPQDPKEMNSNSIDEHEETEESSRMIRRDSEGYIVPEITMEDRMRMLHEHLENDGFLENFSFDEENS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-06-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NNH4</accession>
    <name>A0A1C7NNH4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_01272</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000038">
        <property type="protein sequence ID" value="OBZ90693.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NNH4"/>
    <dbReference type="InParanoid" id="A0A1C7NNH4"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008889806" evidence="1">
        <location>
            <begin position="21"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ90693.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="78" mass="8672" checksum="97E0BAAB90DC75BE" modified="2016-11-30" version="1">MVKLAATFTALSTAASVVLADYSQNGCQYSYSDKGRCVYSCDENACNKSGSWIKDHFHKSMSDKGYDCRLEGDKRMEP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NPQ1</accession>
    <name>A0A1C7NPQ1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Peptidyl-prolyl cis-trans isomerase</fullName>
            <shortName evidence="10">PPIase</shortName>
            <ecNumber evidence="10">5.2.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="primary">cyp13</name>
        <name evidence="15" type="ORF">A0J61_00847</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 10">PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 17">
            <text>[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)</text>
            <dbReference type="Rhea" id="RHEA:16237"/>
            <dbReference type="Rhea" id="RHEA-COMP:10747"/>
            <dbReference type="Rhea" id="RHEA-COMP:10748"/>
            <dbReference type="ChEBI" id="CHEBI:83833"/>
            <dbReference type="ChEBI" id="CHEBI:83834"/>
            <dbReference type="EC" id="5.2.1.8"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3 10">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 10">Belongs to the cyclophilin-type PPIase family. PPIL4 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.2.1.8" evidence="10"/>
    <dbReference type="EMBL" id="LUGH01000022">
        <property type="protein sequence ID" value="OBZ91092.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NPQ1"/>
    <dbReference type="FunCoup" id="A0A1C7NPQ1">
        <property type="interactions" value="1056"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NPQ1"/>
    <dbReference type="InParanoid" id="A0A1C7NPQ1"/>
    <dbReference type="OrthoDB" id="2083at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01921">
        <property type="entry name" value="cyclophilin_RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd12235">
        <property type="entry name" value="RRM_PPIL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.100.10:FF:000015">
        <property type="entry name" value="Peptidyl-prolyl cis-trans isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.330:FF:000287">
        <property type="entry name" value="Peptidyl-prolyl cis-trans isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.100.10">
        <property type="entry name" value="Cyclophilin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035542">
        <property type="entry name" value="CRIP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029000">
        <property type="entry name" value="Cyclophilin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002130">
        <property type="entry name" value="Cyclophilin-type_PPIase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035538">
        <property type="entry name" value="Cyclophilin_PPIL4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45843">
        <property type="entry name" value="PEPTIDYL-PROLYL CIS-TRANS ISOMERASE-LIKE 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45843:SF1">
        <property type="entry name" value="PEPTIDYL-PROLYL CIS-TRANS ISOMERASE-LIKE 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00160">
        <property type="entry name" value="Pro_isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00153">
        <property type="entry name" value="CSAPPISMRASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50891">
        <property type="entry name" value="Cyclophilin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50072">
        <property type="entry name" value="CSA_PPIASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10 15" id="KW-0413">Isomerase</keyword>
    <keyword evidence="12" id="KW-0472">Membrane</keyword>
    <keyword evidence="8 10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 9 10" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="6 10" id="KW-0697">Rotamase</keyword>
    <keyword evidence="12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="12" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="56"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="domain" description="PPIase cyclophilin-type" evidence="13">
        <location>
            <begin position="171"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="14">
        <location>
            <begin position="409"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="502"/>
            <end position="601"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="519"/>
            <end position="529"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="543"/>
            <end position="601"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002388"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010739"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU365081"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="OBZ91092.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="601" mass="69666" checksum="4A78EA504CD50156" modified="2016-11-30" version="1">MSEGSITTSSWKSKFFDFYQWCKIVSISLNVIYMVRTFEDIYDAGSRIDHATSLQYGFQILIGCLMVFCLIGDLIVINTCNQSKLAVANWYWRPGILFFTFTFGNEVINITDRVLNADIVFQNCQQRLMNAARGSSIALVSDVCGLENQLGHLYSTGTMMRNIILCSVLIETSLGDLVIDLYIDECPKTSLNFIKLCKIKYYNFAPFFNVQKDFMAQTGDPTGKGDQGESVYGILNGPSQRYFPAEINPKLKHNKRGMVSMAVAQDASIESGGVSGSQFFITLADDLDYLDGKYTLFGEVVEGFDVLDKMNNAYCDEKGRPFRDIRIKHTIIIDDPFPDPEGLQVPDESPLPTKEQMESMRIADDEDLEEMGDPEEIEKRMREKEAKAHALTLEMIGDLPFAEVKAPENVLFVCKLNPVTRDEDLEMIFSRFGPIHSCEIIRDRQTGDSLSYAFIEFENREDAEEAYFKMQSVLIDDRRINVDFSQSVSKLHKDWISKRTAGNRQSMGGFDNLKKRTRYREDENNDRNNYDLVFEQKRKKTSSSRDDDRRRDDRSSHRRESSRDDERRRKSSHRRDSSREYDRRRDYDRRRRDDDDRRRRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-06-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NPS3</accession>
    <name>A0A1C7NPS3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_01052</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000029">
        <property type="protein sequence ID" value="OBZ90909.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NPS3"/>
    <dbReference type="InParanoid" id="A0A1C7NPS3"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ90909.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="79" mass="8890" checksum="A1FF66BFEE4BF8C7" modified="2016-11-30" version="1">MPSKNDSPHLCLDTVVIDTRSSISSQSPSELSPYLLTSCNENLHAEQTYHAVQIASKNYCFAHNTYHIMSWCPICAFKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NPV9</accession>
    <name>A0A1C7NPV9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">DNA-directed RNA polymerase</fullName>
            <ecNumber evidence="10">2.7.7.6</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">RPO41</name>
        <name evidence="13" type="ORF">A0J61_00791</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9 15">
            <text>RNA(n) + a ribonucleoside 5'-triphosphate = RNA(n+1) + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:21248"/>
            <dbReference type="Rhea" id="RHEA-COMP:14527"/>
            <dbReference type="Rhea" id="RHEA-COMP:17342"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61557"/>
            <dbReference type="ChEBI" id="CHEBI:140395"/>
            <dbReference type="EC" id="2.7.7.6"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the phage and mitochondrial RNA polymerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.6" evidence="10"/>
    <dbReference type="EMBL" id="LUGH01000020">
        <property type="protein sequence ID" value="OBZ91143.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="FunCoup" id="A0A1C7NPV9">
        <property type="interactions" value="149"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NPV9"/>
    <dbReference type="InParanoid" id="A0A1C7NPV9"/>
    <dbReference type="OrthoDB" id="276422at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034245">
        <property type="term" value="C:mitochondrial DNA-directed RNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003899">
        <property type="term" value="F:DNA-directed RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001018">
        <property type="term" value="F:mitochondrial promoter sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006390">
        <property type="term" value="P:mitochondrial transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.150.20:FF:000041">
        <property type="entry name" value="DNA-directed RNA polymerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.280:FF:000001">
        <property type="entry name" value="DNA-directed RNA polymerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.260">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.280">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.20">
        <property type="entry name" value="5' to 3' exonuclease, C-terminal subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1320.10">
        <property type="entry name" value="DNA-directed RNA polymerase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024075">
        <property type="entry name" value="DNA-dir_RNA_pol_helix_hairp_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046950">
        <property type="entry name" value="DNA-dir_Rpol_C_phage-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002092">
        <property type="entry name" value="DNA-dir_Rpol_phage-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043502">
        <property type="entry name" value="DNA/RNA_pol_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037159">
        <property type="entry name" value="RNA_POL_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029262">
        <property type="entry name" value="RPOL_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10102">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10102:SF0">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00940">
        <property type="entry name" value="RNA_pol"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14700">
        <property type="entry name" value="RPOL_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01311">
        <property type="entry name" value="RPOL_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56672">
        <property type="entry name" value="DNA/RNA polymerases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00900">
        <property type="entry name" value="RNA_POL_PHAGE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00489">
        <property type="entry name" value="RNA_POL_PHAGE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 10 13" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="7" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5 10" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 10" id="KW-0804">Transcription</keyword>
    <keyword evidence="4 10" id="KW-0808">Transferase</keyword>
    <keyword evidence="6" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="DNA-directed RNA polymerase N-terminal" evidence="12">
        <location>
            <begin position="306"/>
            <end position="631"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1001"/>
            <end position="1030"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1228"/>
            <end position="1262"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="1236"/>
            <end position="1252"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009493"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00048552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU003805"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM01311"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="OBZ91143.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="1296" mass="145347" checksum="070A9279C73623D5" modified="2016-11-30" version="1">MSLSLVRQTATKGRLFPIHRYQRQTLLKCASIAIRYNSSSATVEASSSSAAESKPLNNRRQHIIFPSPALDNFTETTRVLPSSIAEQFAILKACIASGSMERAERIMTELYKTKPKEMKMFADINVYNSFLNGFVEAPDKPMTKNCLSWFDHMKAYGVNADADTFAIIVKGFLKVKSYHTARALLRDLSETENITVDQMLRSQYLSKDDVHLFRQMVDILKTGGHDVNMEQLLNELENRTDNILGKPAAKEVLSKTRLAIDTAKNDVKVEVVPEVKPTKSIGVHFLQEQLAALRDPHASAKMDPFELQLALEQQGYEMALQKLLHSKEQSIERGDTLNAMNLTPLKRIMWTWHQSMMPLIKEEIERCDAATLREADRRAYGPFLKLLPPQTLSIVTILELLRLHNSSGIGDGMKTARAIIDIGKAVEMEYNAVQIKRRASSSSILDRNTDPQALFSNARLFNLAVRKAQSKIEQNALNKEVDILASDWNPVWPSTIRAKVGSVLTSLLLEAAKIPVPSKDPETGMKIIENIPAFFHTYQYVHGKRVGIIKFSEQLTRMLSREPVRDTLHPRLLPMLVHPRPWLSYNSGGYLSTKSVCMRIKDSAEQLVYLSKASEQDHLTQVLAGLDVLGSTRWRVNKDVFKVILDVWNSGEALADIPPAIGEPAPLPPKPANYDTDPKAKFLWVSEVKQQQTNEKNFHSLRCDVNYKVETARAFLNLPMYFPHNMDFRGRAYPMPPTLNHLGNDLCRGLLHFDEAKPLGPRGWRWLKIHLANLYGYDKHSFTEREQYTMDNIEHILDSVDKPLEGKRWWLKAENPWQCLAACYEVAAAFRSGKPEEFKSQLPVHQDGTCNGLQHYAALGGDLAGARAVNLAAGDRPADVYTGVADMVNSTINKSAAEGDEMAKLLQGNISRKVVKQTVMTNVYGVTFVGARAQIENRLRENPNIPREKVYALSGYLAKVVFSSLGEMFAGARQIQDWLTDSARRIARSVPLETLQDAGIVPGGTNIEKTATGQKGKRSKKSKEFSARNPSASQMSSVIWTTPLGLPIVQPYRRSGKKQVATLLQTIFIEDPDASRPVNAMKQSTAFPPNFIHSLDATHMLLSAVACHKKGMTFASVHDSYWTHACDVDNMNEVIRDQFIELHSQPIMENLIAEFKERYKDYRVPHSALMSETSTTSAKKTIGGSEDDISDDGIGSSLFGDPLAMEKELEQEKFKKESEKKDALKAIFGLGGTPETDGDGDEDLEEEVEEEDASPKKKKGAAQKYKHSWEPLTFAPLPAKGEFDINEVKKSQYFFH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NQ33</accession>
    <name>A0A1C7NQ33_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_02588</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000099">
        <property type="protein sequence ID" value="OBZ89364.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NQ33"/>
    <dbReference type="InParanoid" id="A0A1C7NQ33"/>
    <dbReference type="OrthoDB" id="2378114at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ89364.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="254" mass="29232" checksum="90B19C3231258469" modified="2016-11-30" version="1">MVNTTSSFFGFKQSPSYPARELLGLIMKTLKQNDSHMRLEENQQLGEGFKSVTRPWALVLAKEPNVFEDTLKNRIVSIHTTGATALDNMPPEERLWLDAIQVCRVENIHQLRAIVCSLHMKETGKKAQNIVQWIEREKDGQPPNLIVVVDLLDYLVNQQEKLNDPLRYLYIDEGELSRILSNLVETCIYETDVGSIYWEKSLGRKVGHFTELLITDKECLPPLSQITTDISPFVKDGIQKLHRILNYYLDSLYI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NQ81</accession>
    <name>A0A1C7NQ81_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_00879</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000023">
        <property type="protein sequence ID" value="OBZ91069.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NQ81"/>
    <dbReference type="STRING" id="101091.A0A1C7NQ81"/>
    <dbReference type="InParanoid" id="A0A1C7NQ81"/>
    <dbReference type="OrthoDB" id="2447509at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45786:SF74">
        <property type="entry name" value="ATP-DEPENDENT DNA HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45786">
        <property type="entry name" value="DNA BINDING PROTEIN-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ91069.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="112" mass="12408" checksum="D710A1DA3F480537" modified="2016-11-30" version="1">MREFQQPANIVLSFSFVVVEGKSVLPSLQSTPSEIADYLKSSDDISKEFRKNIRLLCFTSLGMNLNLNLANNRSGAYTFRIQGSPYHLVGSAVPTEGANLKFAQICVYDAEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NQD6</accession>
    <name>A0A1C7NQD6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_00735</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000018">
        <property type="protein sequence ID" value="OBZ91228.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NQD6"/>
    <dbReference type="STRING" id="101091.A0A1C7NQD6"/>
    <dbReference type="InParanoid" id="A0A1C7NQD6"/>
    <dbReference type="OrthoDB" id="9451547at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="94"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="278"/>
            <end position="312"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ91228.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="511" mass="58996" checksum="77BF5A17F1FBB40D" modified="2016-11-30" version="1">MLASQIKTRPRLQVIPRHKISQSTPTDKLHHEEEPLCSPAESNASFLSSVVSGIAEKSASELGSLLKNAYKSLREKEKNLLLAAEIGKSLLEHNQALKSDYDKLLENVRNCEIETKKQQEEHKENENMRFISNKRSYDEMIESLERKNAELQLLLEQTQKESDLTNQAYHKKHQKLEAEIEVLKHDLDLAAQKVQDLEEIKKIQHVGQLDERREFEQRRSEDLELLDELTKKLGELCMENKHLQISKKSVEDKLIVSLNDLNALKREFEQFELTQQNYMTLQEAFEQQRKHIKELNDSLEDHRMILSKLRDRGVWSLNTPSLTSKRSASSTIGSFLLNQKQQRSLLGELEHVWRQNHTVKKSASETNLSDLSSDEGLSSKLYEMTERHLTSFYNASADYAVDTLLSTLGIDDRTFLEDAEELMTKSLSDSSLFGPEGNGTAYAEHDLYPALIKRQTQTQVESLPKSGLINRILFHIRYLFHSLFRWCRFAIILSAAVFINLWKGPDLLLEH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NQQ5</accession>
    <name>A0A1C7NQQ5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="16">Double-strand break repair protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="21" type="primary">MRE11A</name>
        <name evidence="21" type="ORF">A0J61_00550</name>
    </gene>
    <organism evidence="21 22">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="21 22" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="21 22">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="16">Core component of the MRN complex, which plays a central role in double-strand break (DSB) repair, DNA recombination, maintenance of telomere integrity and meiosis. The MRN complex is involved in the repair of DNA double-strand breaks (DSBs) via homologous recombination (HR), an error-free mechanism which primarily occurs during S and G2 phases. The complex (1) mediates the end resection of damaged DNA, which generates proper single-stranded DNA, a key initial steps in HR, and is (2) required for the recruitment of other repair factors and efficient activation of ATM and ATR upon DNA damage. Within the MRN complex, MRE11 possesses both single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. MRE11 first endonucleolytically cleaves the 5' strand at DNA DSB ends to prevent non-homologous end joining (NHEJ) and licence HR. It then generates a single-stranded DNA gap via 3' to 5' exonucleolytic degradation, which is required for single-strand invasion and recombination.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 16">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Chromosome</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2 16">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 16 18">Belongs to the MRE11/RAD32 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="21">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000012">
        <property type="protein sequence ID" value="OBZ91423.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NQQ5"/>
    <dbReference type="FunCoup" id="A0A1C7NQQ5">
        <property type="interactions" value="740"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NQQ5"/>
    <dbReference type="InParanoid" id="A0A1C7NQQ5"/>
    <dbReference type="OrthoDB" id="30417at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140445">
        <property type="term" value="C:chromosome, telomeric repeat region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030870">
        <property type="term" value="C:Mre11 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035861">
        <property type="term" value="C:site of double-strand break"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008296">
        <property type="term" value="F:3'-5'-DNA exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004017">
        <property type="term" value="F:AMP kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003691">
        <property type="term" value="F:double-stranded telomeric DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051880">
        <property type="term" value="F:G-quadruplex DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030145">
        <property type="term" value="F:manganese ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0060090">
        <property type="term" value="F:molecular adaptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000014">
        <property type="term" value="F:single-stranded DNA endodeoxyribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043047">
        <property type="term" value="F:single-stranded telomeric DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006284">
        <property type="term" value="P:base-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010791">
        <property type="term" value="P:DNA double-strand break processing involved in repair via synthesis-dependent strand annealing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990918">
        <property type="term" value="P:double-strand break repair involved in meiotic recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000727">
        <property type="term" value="P:double-strand break repair via break-induced replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006303">
        <property type="term" value="P:double-strand break repair via nonhomologous end joining"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035753">
        <property type="term" value="P:maintenance of DNA trinucleotide repeats"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010780">
        <property type="term" value="P:meiotic DNA double-strand break formation involved in reciprocal meiotic recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097552">
        <property type="term" value="P:mitochondrial double-strand break repair via homologous recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007095">
        <property type="term" value="P:mitotic G2 DNA damage checkpoint signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031573">
        <property type="term" value="P:mitotic intra-S DNA damage checkpoint signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0062176">
        <property type="term" value="P:R-loop processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000723">
        <property type="term" value="P:telomere maintenance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd00840">
        <property type="entry name" value="MPP_Mre11_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.21.10:FF:000011">
        <property type="entry name" value="Double-strand break repair protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.110.110">
        <property type="entry name" value="Mre11, capping domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003701">
        <property type="entry name" value="Mre11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038487">
        <property type="entry name" value="Mre11_capping_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007281">
        <property type="entry name" value="Mre11_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041796">
        <property type="entry name" value="Mre11_N"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00583">
        <property type="entry name" value="mre11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10139">
        <property type="entry name" value="DOUBLE-STRAND BREAK REPAIR PROTEIN MRE11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10139:SF1">
        <property type="entry name" value="DOUBLE-STRAND BREAK REPAIR PROTEIN MRE11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04152">
        <property type="entry name" value="Mre11_DNA_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000882">
        <property type="entry name" value="DSB_repair_MRE11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01347">
        <property type="entry name" value="Mre11_DNA_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="Metallo-dependent phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0158">Chromosome</keyword>
    <keyword evidence="9 16 18" id="KW-0227">DNA damage</keyword>
    <keyword evidence="12 16 18" id="KW-0234">DNA repair</keyword>
    <keyword evidence="8 16 18" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="11 16 18" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="10 16 18" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="13 16 18" id="KW-0464">Manganese</keyword>
    <keyword evidence="15 16 18" id="KW-0469">Meiosis</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 16 18" id="KW-0540">Nuclease</keyword>
    <keyword evidence="14 16 18" id="KW-0539">Nucleus</keyword>
    <keyword evidence="22" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Mre11 DNA-binding" evidence="20">
        <location>
            <begin position="293"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="19">
        <location>
            <begin position="512"/>
            <end position="712"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="19">
        <location>
            <begin position="512"/>
            <end position="521"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="19">
        <location>
            <begin position="537"/>
            <end position="551"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="19">
        <location>
            <begin position="574"/>
            <end position="586"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="19">
        <location>
            <begin position="588"/>
            <end position="598"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="19">
        <location>
            <begin position="599"/>
            <end position="611"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="19">
        <location>
            <begin position="650"/>
            <end position="659"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="17">
        <location>
            <position position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00009028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PIRNR" id="PIRNR000882"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="PIRSR" id="PIRSR000882-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="RuleBase" id="RU003447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="SMART" id="SM01347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="EMBL" id="OBZ91423.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="712" mass="80492" checksum="F9B23E18EEFB162D" modified="2016-11-30" version="1">MTQQNNDNAFKILIATDNHLGYLERDPIRGQDSFETFEEILQIAEAEKVDFILLGGDLFHHNRPSRSCLYRTMKMIRRHCFGERESKVWIASDQSVNFADEFSTANYLDENLNISIPVFSIHGNHDDPSGVDNLCALNLLSVSGMVNYFGASQSIEDVVVHPILMQKGQSKLALYGLGNIREERLHRQWRGGHVKFMRPQEDGTGDGWKDCFNLFVFHQNRARHGPTSHIPEEFLDGFIDLVFWGHEHECRIHPEEFQYFAVTQPGSSVATSLSQGEAEPKHVGLLTIEGDEYHLEKIRLKTIRPFQFTTITLSRVEGLAPSDTKGIQHYLEGVVESLIEKAKLEWKEQQQQSRYRLHPHLEDEPNMEMPMPLIRIRVDYSGGYETFNPQQFGQKFIDRVANPKDILKFQRTRPETQVRLKPSEIMNDLATAIPERLDTLKVEDLVSELLSRDLSILPENGLEEAVKSLVEKSDKEAIRSFVSNSVAQTRESMTASYEHLTVDYIVQKSTEAKQSQIQPSRRNIAAVPPVEEMRGSTEISSNTVSIVSQPAFSEDDNDDMQDMILSSSNPPPSQSSRQRSSTPSRGGSRGRGRGRARGHSVANSRARSNNNGHDDSNDDMDEDLSNISSSLPPSRTRRVATEAPSYVILSEDDQDEDDYHEVQLNQKRAKRAAPSPSPPPLMSTQSSITPLSQSTQKKRRTLPAASLSQKKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NQU3</accession>
    <name>A0A1C7NQU3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Sorting nexin mvp1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">mvp1_1</name>
        <name evidence="11" type="ORF">A0J61_00645</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the sorting nexin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000015">
        <property type="protein sequence ID" value="OBZ91320.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NQU3"/>
    <dbReference type="InParanoid" id="A0A1C7NQU3"/>
    <dbReference type="OrthoDB" id="2289269at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005768">
        <property type="term" value="C:endosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032266">
        <property type="term" value="F:phosphatidylinositol-3-phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006623">
        <property type="term" value="P:protein targeting to vacuole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042147">
        <property type="term" value="P:retrograde transport, endosome to Golgi"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.910">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009449">
        <property type="entry name" value="Sec2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028662">
        <property type="entry name" value="SNX8/Mvp1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045734">
        <property type="entry name" value="Snx8_BAR_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47554">
        <property type="entry name" value="SORTING NEXIN MVP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47554:SF1">
        <property type="entry name" value="SORTING NEXIN MVP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06428">
        <property type="entry name" value="Sec2p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19566">
        <property type="entry name" value="Snx8_BAR_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144284">
        <property type="entry name" value="Sec2 N-terminal region"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="domain" description="GDP/GTP exchange factor Sec2 N-terminal" evidence="9">
        <location>
            <begin position="44"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="domain" description="Sorting nexin 8/Mvp1 BAR" evidence="10">
        <location>
            <begin position="233"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="86"/>
            <end position="135"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF06428"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF19566"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="OBZ91320.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="374" mass="43250" checksum="20165600A9A764AE" modified="2016-11-30" version="1">MQVPKPLPALLAPSVTTIDISTDSRYLSSSIACFDTLPYEIQSKALLDTSKSYHHATTQAQLTEIQELRGDLIKLNHKYIQQMERAQIAQQARLQTEAELEDLSIKLFEQANGMVSEEKRKRVDAEKRAIQLENTLTYVVQELMQLKEFRSRFEIRTIEDEVMLKHTKSSFIAPSGSAARKMPNRLDDLCMDNRPIASLEDFLTWRPTAPIDVAKHGFIQIRVNIDNFINEXTDGVLENLKQFRDLLVSFRDLDERRARLSNNQTDAISKRIQANRSKLHQNKGVPGLEAETQKLEESVRTDEKELAFQQDREVFIRYSLWSELIYLHKQQAFVSTLYQNFTKSAVHFSKLRAENWQDLEEPAFNMPSDIASFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NQX7</accession>
    <name>A0A1C7NQX7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">uS12 prolyl 3,4-dihydroxylase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">ofd1</name>
        <name evidence="14" type="ORF">A0J61_00482</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>[ribosomal protein uS12]-(3S)-3-hydroxy-L-proline + 2-oxoglutarate + O2 = [ribosomal protein uS12]-(3S)-3,4-dihydroxy-L-proline + succinate + CO2</text>
            <dbReference type="Rhea" id="RHEA:54160"/>
            <dbReference type="Rhea" id="RHEA-COMP:13817"/>
            <dbReference type="Rhea" id="RHEA-COMP:13818"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:30031"/>
            <dbReference type="ChEBI" id="CHEBI:85428"/>
            <dbReference type="ChEBI" id="CHEBI:138052"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>[ribosomal protein uS12]-L-proline + 2-oxoglutarate + O2 = [ribosomal protein uS12]-(3S)-3-hydroxy-L-proline + succinate + CO2</text>
            <dbReference type="Rhea" id="RHEA:54156"/>
            <dbReference type="Rhea" id="RHEA-COMP:13816"/>
            <dbReference type="Rhea" id="RHEA-COMP:13818"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:30031"/>
            <dbReference type="ChEBI" id="CHEBI:50342"/>
            <dbReference type="ChEBI" id="CHEBI:85428"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>L-ascorbate</name>
            <dbReference type="ChEBI" id="CHEBI:38290"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the TPA1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000010">
        <property type="protein sequence ID" value="OBZ91503.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NQX7"/>
    <dbReference type="FunCoup" id="A0A1C7NQX7">
        <property type="interactions" value="436"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NQX7"/>
    <dbReference type="InParanoid" id="A0A1C7NQX7"/>
    <dbReference type="OrthoDB" id="430522at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031418">
        <property type="term" value="F:L-ascorbic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031543">
        <property type="term" value="F:peptidyl-proline dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009896">
        <property type="term" value="P:positive regulation of catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010604">
        <property type="term" value="P:positive regulation of macromolecule metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006449">
        <property type="term" value="P:regulation of translational termination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.120.620:FF:000014">
        <property type="entry name" value="Prolyl 3,4-dihydroxylase TPA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.620">
        <property type="entry name" value="q2cbj1_9rhob like domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005123">
        <property type="entry name" value="Oxoglu/Fe-dep_dioxygenase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019601">
        <property type="entry name" value="Oxoglutarate/Fe-dep_Oase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006620">
        <property type="entry name" value="Pro_4_hyd_alph"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039558">
        <property type="entry name" value="TPA1/OFD1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051842">
        <property type="entry name" value="uS12_prolyl_hydroxylase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12117">
        <property type="entry name" value="HISTONE ACETYLTRANSFERASE COMPLEX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12117:SF0">
        <property type="entry name" value="PROLYL 3-HYDROXYLASE OGFOD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13661">
        <property type="entry name" value="2OG-FeII_Oxy_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10637">
        <property type="entry name" value="Ofd1_CTDD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00702">
        <property type="entry name" value="P4Hc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51471">
        <property type="entry name" value="FE2OG_OXY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="8" id="KW-0408">Iron</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0847">Vitamin C</keyword>
    <feature type="domain" description="Fe2OG dioxygenase" evidence="13">
        <location>
            <begin position="128"/>
            <end position="234"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001961"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022896"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00047444"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00051966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00081607"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="OBZ91503.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="510" mass="57529" checksum="E4D59AD86CC6C14B" modified="2016-11-30" version="1">MTNKKQKLDTEEHKEKFHEGLLEQECVDTLKSAYKVSKPYLHCKIDTLMNDDLLQKVRKEILSSLHFTLKETDIYKVNQTGDLANLDGLPKEELKQLSSLFELRNAIYSPAFRSFVSEVTGCGPLSGSKTDMSINSYQQGCHLLNHDDVIGTRRVSYILYLTDPAKPWDPKDGGALELYPVIKKGTPANEPTVTIPPQWNQFVMFTVQPGHSFHTVEEVVGTGNRLSISGWFHIPQEGEIGYSADSKNEDAAKSSLEQLQEEKDSSDQFVKYDVQNPQEEEIVGLTEEVMVELAEWMNPQYLDLAMLSQMSEKFLEESAIQCKEILNDKTLEKLVQATTELDKQDKLYTGEDGIAPHGTGVRKGWVVEGPPHRSRFMVHQKTDEEDIFDYLKKQFESESFRIWLVTVAQLMPVGYRGQARRFRPGHDYTLATTNTRGQGVLDVTFCHVNKPEAWEDGDRGGYECYMAPHDEEEDAAVYKAADEDGALLTLPAGRNEILASLSISGLSKSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NQZ3</accession>
    <name>A0A1C7NQZ3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Tubulin alpha chain</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">Tuba1c_0</name>
        <name evidence="14" type="ORF">A0J61_02271</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>GTP + H2O = GDP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:19669"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58189"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="9">
            <dbReference type="Rhea" id="RHEA:19670"/>
        </physiologicalReaction>
    </comment>
    <comment type="subunit">
        <text evidence="2 10">Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 10">Belongs to the tubulin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000083">
        <property type="protein sequence ID" value="OBZ89684.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NQZ3"/>
    <dbReference type="FunCoup" id="A0A1C7NQZ3">
        <property type="interactions" value="116"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NQZ3"/>
    <dbReference type="InParanoid" id="A0A1C7NQZ3"/>
    <dbReference type="OrthoDB" id="1662883at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005200">
        <property type="term" value="F:structural constituent of cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007017">
        <property type="term" value="P:microtubule-based process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02186">
        <property type="entry name" value="alpha_tubulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.600:FF:000005">
        <property type="entry name" value="Tubulin alpha chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1330.20:FF:000001">
        <property type="entry name" value="Tubulin alpha chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1440:FF:000019">
        <property type="entry name" value="Tubulin alpha chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.600">
        <property type="entry name" value="Helix hairpin bin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.20">
        <property type="entry name" value="Tubulin/FtsZ, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1440">
        <property type="entry name" value="Tubulin/FtsZ, GTPase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002452">
        <property type="entry name" value="Alpha_tubulin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013838">
        <property type="entry name" value="Beta-tubulin_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008280">
        <property type="entry name" value="Tub_FtsZ_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000217">
        <property type="entry name" value="Tubulin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037103">
        <property type="entry name" value="Tubulin/FtsZ-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018316">
        <property type="entry name" value="Tubulin/FtsZ_2-layer-sand-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036525">
        <property type="entry name" value="Tubulin/FtsZ_GTPase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023123">
        <property type="entry name" value="Tubulin_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017975">
        <property type="entry name" value="Tubulin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003008">
        <property type="entry name" value="Tubulin_FtsZ_GTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11588">
        <property type="entry name" value="TUBULIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00091">
        <property type="entry name" value="Tubulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03953">
        <property type="entry name" value="Tubulin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01162">
        <property type="entry name" value="ALPHATUBULIN"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01161">
        <property type="entry name" value="TUBULIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00864">
        <property type="entry name" value="Tubulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00865">
        <property type="entry name" value="Tubulin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55307">
        <property type="entry name" value="Tubulin C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52490">
        <property type="entry name" value="Tubulin nucleotide-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00227">
        <property type="entry name" value="TUBULIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00228">
        <property type="entry name" value="TUBULIN_B_AUTOREG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 10" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0460">Magnesium</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 10" id="KW-0493">Microtubule</keyword>
    <keyword evidence="5 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tubulin/FtsZ GTPase" evidence="12">
        <location>
            <begin position="47"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="domain" description="Tubulin/FtsZ 2-layer sandwich" evidence="13">
        <location>
            <begin position="246"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="431"/>
            <end position="450"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00049117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM00864"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="SMART" id="SM00865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="OBZ89684.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="450" mass="50096" checksum="303DE6AE1CBCFCBE" modified="2016-11-30" version="1">MREIISVHVGQAGIQIGNACWELYCLEHGIQPDGIIPQENATDNASFSTFFSETGNGKYVPRTVFVDLEPTVVDEVRTGTYRQLFHPEQLITGKEDAANNYARGHYTVGKELVDSVLDRIRKLADACTGLQGFLVFHSFGGGTGSGFGALLMERLSVDYGKKSKLEFSVYPAPQVSTAVVEPYNSILTTHTTLEHSDCSFMVDNEAIYDICRRNLDIERPTYQNLNRLIAQVVSSITASLRFDGSLNVDMNEFQTNLVPYPRIHFPLVTYAPIISASKAYHEQLSVAEITYSCFEPNNQMVKCDPRNGKYMACCLLYRGDVVPKDTNAAIGTIKTKRTIQFVDWCPTGFKVGINNRAPAVVPGGDLANVQRAVCMLSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDLAALEKDYEEVGSDSLGDSEIEEEDVEY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NR12</accession>
    <name>A0A1C7NR12_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Coth-domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_00378</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000008">
        <property type="protein sequence ID" value="OBZ91575.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NR12"/>
    <dbReference type="STRING" id="101091.A0A1C7NR12"/>
    <dbReference type="InParanoid" id="A0A1C7NR12"/>
    <dbReference type="OrthoDB" id="10267127at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014867">
        <property type="entry name" value="Spore_coat_CotH_CotH2/3/7"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40050">
        <property type="entry name" value="INNER SPORE COAT PROTEIN H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40050:SF1">
        <property type="entry name" value="INNER SPORE COAT PROTEIN H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08757">
        <property type="entry name" value="CotH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008889835" description="Coth-domain-containing protein" evidence="1">
        <location>
            <begin position="20"/>
            <end position="585"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ91575.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="585" mass="66041" checksum="17DC1EB00C817401" modified="2016-11-30" version="1">MHLRKAILCSILLIQATYAADILYSVILNSPSTDTGIVIDDTVYSLKPSKESNILFQGKAPANSPYSYCKLEKVTAKIIECENFKRKGINTSSLNEFYGRNWNVKALSTFESVDSIPKRFNRQPNNSDLHPVGEIPTIYVQADQSDIDNIHTHYLQDIQVKANITFISTKSTQTFSNAKFEIGGRSSRRLTKFSYNFKIDKKSKNSLGGYKKLKLRSTVTDPSYMREFIVTEMLNAANQPASRASYVRVFINDRPVGLYSMLEKYDKTWLENEFGDSSTGILYESEGGSRNSRADLSYKGAEPSAYESSAYSVSEESEMGASGLDDLSSFIQFIHDQQQFQKKADDKSISATISKWEEQIDVEGFLVSMASEFAFGLFDAYLQNTNNYFLYKCPKQNRFVWIMWDFDLSMGSGPVNMKKIAVGDYTSFEGFKTRPLITALLKINEYRALFEKHLDSIMNKLYNPLVAFPIIDSVAEFIRDDVAWDKSLPHVGKGPEYVGPILGNIINHNHNNQSNNNIGVPSSLSLITAAEYVIRLNSDVSFDKAINGPTGHASLYGLKEWIKTKSDNYKKKTRYDPIIDLPLKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NR28</accession>
    <name>A0A1C7NR28_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_00538</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000012">
        <property type="protein sequence ID" value="OBZ91420.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NR28"/>
    <dbReference type="InParanoid" id="A0A1C7NR28"/>
    <dbReference type="OrthoDB" id="6244550at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ91420.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="167" mass="19419" checksum="A720C681DA22DC38" modified="2016-11-30" version="1">MNLTQSSRIEFAELSEQVKTILCAHHKHYEKLISNDDPHETFEIYLIEWATGIKPFYERYIESLAKLSSSSCQEIIPSALWQPSPNSTHKQEKPITIEAPLQQLETYKYLFEQAHQANIIHKSTLQQLDQEFDKLMNSIPVSLKSNPELLHNQIDCTRSLIETFSLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NR86</accession>
    <name>A0A1C7NR86_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Origin recognition complex subunit 3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">ORC3</name>
        <name evidence="14" type="ORF">A0J61_00505</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent. The specific DNA sequences that define origins of replication have not been identified yet. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. Binds histone H3 and H4 trimethylation marks H3K9me3, H3K27me3 and H4K20me3.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Component of ORC, a complex composed of at least 6 subunits: ORC1, ORC2, ORC3, ORC4, ORC5 and ORC6. ORC is regulated in a cell-cycle dependent manner. It is sequentially assembled at the exit from anaphase of mitosis and disassembled as cells enter S phase.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ORC3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000011">
        <property type="protein sequence ID" value="OBZ91439.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="FunCoup" id="A0A1C7NR86">
        <property type="interactions" value="418"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NR86"/>
    <dbReference type="InParanoid" id="A0A1C7NR86"/>
    <dbReference type="OrthoDB" id="10265211at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031261">
        <property type="term" value="C:DNA replication preinitiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005664">
        <property type="term" value="C:nuclear origin of replication recognition complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005656">
        <property type="term" value="C:nuclear pre-replicative complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003688">
        <property type="term" value="F:DNA replication origin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006270">
        <property type="term" value="P:DNA replication initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd20704">
        <property type="entry name" value="Orc3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020795">
        <property type="entry name" value="ORC3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045663">
        <property type="entry name" value="ORC3_ins"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045667">
        <property type="entry name" value="ORC3_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040855">
        <property type="entry name" value="ORC_WH_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12748">
        <property type="entry name" value="ORIGIN RECOGNITION COMPLEX SUBUNIT 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12748:SF0">
        <property type="entry name" value="ORIGIN RECOGNITION COMPLEX SUBUNIT 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19675">
        <property type="entry name" value="ORC3_ins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07034">
        <property type="entry name" value="ORC3_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18137">
        <property type="entry name" value="WHD_ORC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0235">DNA replication</keyword>
    <keyword evidence="6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="4" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Origin recognition complex subunit 3 N-terminal" evidence="11">
        <location>
            <begin position="16"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="domain" description="Origin recognition complex subunit 3 insertion" evidence="13">
        <location>
            <begin position="427"/>
            <end position="673"/>
        </location>
    </feature>
    <feature type="domain" description="Origin recognition complex subunit 3 winged helix C-terminal" evidence="12">
        <location>
            <begin position="686"/>
            <end position="796"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="31"/>
            <end position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00019085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00026084"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00045241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF07034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF18137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF19675"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="OBZ91439.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="799" mass="92648" checksum="B558B8B6DDE0ECED" modified="2016-11-30" version="1">MTLADSASSALVRDQLDSISEGCFLVLPAKKRSHTGPSQSRTTKRNKPTNIDNKQSILHNGFQQLLNGQESYQAMLYRKQSFESAWHKIETMIHDTLLDMNESAVQKICHFVDKEHDSKDSLISLPFHEIPTALVFAGINTPDHGKQFQHIAARLSQPPSMDNERQRDNLVILLHSKDCTNIKAMMRVMIEKFMSLPSKSKDRVDIEMQDLDEENEEEDLDDEDLIHTTSHTNSGYQFGAKAVVRPSKCLPYDMRLLEGWYKNTARYYQKQPNLIIILQDFESFEPSVLQDFFTICSNYRQNLPIICIIGIATSTEILHQSLTKATIGLLRIEKFRLELSEVWFKRILEQLFLESTDTLKFXARPYKFLLDRFYLYDFSISKVTASLKYALMHQYYGNPLSVFLSLLEKDQQDMQQTVESWLYDDLLNEHHVTHTRMLSSFKSYIESLAQIDPKQALCLLEDDHTLLVQTVPSLLSEIKIYQKQFKLGFNLIVSLQAQFPRFAGLRKSRHLILLESLQTRATTDTDETQKTVHLLANLVRKMDEEHISQLLIEWRKLVDQAAYQDINQPVLEQLSLWEERYQNLMDADDNYTARMERKAKLLEGMVLPEDGSGGRHTETAKKVQTQSIEHIKKKGTEASKIALSIADWIERTVIHYLRPYNTMPLYEIVYYTNVALHEKSFAPQPRASVQTALTQPQHYINCSCCSIEKSDQILPSEPDTCILYKLYLECGRMINLYDWYVAFESFVEREGRPVGKQTLLKNEVQARFIRSVAELQFLGFIKPTQRKTDHVIRLTWSNI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NRC4</accession>
    <name>A0A1C7NRC4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">DNA damage-binding protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">DDB1_0</name>
        <name evidence="6" type="ORF">A0J61_00399</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000008">
        <property type="protein sequence ID" value="OBZ91578.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="FunCoup" id="A0A1C7NRC4">
        <property type="interactions" value="898"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NRC4"/>
    <dbReference type="InParanoid" id="A0A1C7NRC4"/>
    <dbReference type="OrthoDB" id="433457at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018846">
        <property type="entry name" value="Beta-prop_RSE1/DDB1/CPSF1_1st"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058543">
        <property type="entry name" value="Beta-prop_RSE1/DDB1/CPSF1_2nd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050358">
        <property type="entry name" value="RSE1/DDB1/CFT1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004871">
        <property type="entry name" value="RSE1/DDB1/CPSF1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10644">
        <property type="entry name" value="DNA REPAIR/RNA PROCESSING CPSF FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10433">
        <property type="entry name" value="Beta-prop_RSE1_1st"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23726">
        <property type="entry name" value="Beta-prop_RSE1_2nd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03178">
        <property type="entry name" value="CPSF_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RSE1/DDB1/CPSF1 first beta-propeller" evidence="4">
        <location>
            <begin position="18"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="domain" description="RSE1/DDB1/CPSF1 second beta-propeller" evidence="5">
        <location>
            <begin position="426"/>
            <end position="738"/>
        </location>
    </feature>
    <feature type="domain" description="RSE1/DDB1/CPSF1 C-terminal" evidence="3">
        <location>
            <begin position="787"/>
            <end position="883"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="885"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF03178"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF10433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF23726"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OBZ91578.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="885" mass="98536" checksum="86B01C75F9C80C4D" modified="2016-11-30" version="1" fragment="single">TMTYHKYVVTAQKPTATQLSIKGSFISPHETNLILGKGTRIEVYTLTPDGLKPTIEFSVHGTIIALRLYIPKDKDKASLFLLTSRHKYCTLSYDTSQQQIITESSGEIGFPGQPRKETIDSTLVVDTSCRYFATSLYDSTVTIIIPDIFKSKDYVPTSQPLRKISLRAKDGKRRQQQDHIIQSPPDYINISLHDKHIVSLAFLNDDSPTPTLLILYDDPLGRRYLQQFTLDTKNRQLVPGDVLMDHFESDANLLISMPALLGGVVLIAGKFIRYLKPNQPPIAIGIRPSTITSFSIMNEQGTRILLGDAEGLLYLLNLHIFENKVDSLSFIALGSISAPSCLTYLGNEVVFVGSTVADSQIIHIRRTSTSETGETLSVIDELPNLGPITDFCVADLDKQGQTQLITCSGVGKDSSLRIIRNGVGLNELAAIQISGVKGVWALRPSFEETFDDMLVLSFVNQTRLLALRGNGMTQLESHSALDLHARTLIXSNVKNDMLIQVTDKSIRLMSSHNHGQLIDQWTPNQPNTHITVASVNPTQCVISTGFGELLAFELSQQGLRLIGSAQLDNEVSCIDISPIDTEHPYQSNVVAVGTWSNVGVCLLTLPDLRFITEEKLAGTIMPRSLLMAQFENICYLLVALGDGQFYNFKLDVREGKLFDKKRSFLGKLPIQLARFTSNGTTHVFAASDKPSVIHSRNKKLIYSSVNLREVRHVSSFNSLSFPDAVALATKDGLIIGQMEEIQKLHITKIPTKDTPRRIAYQEASRTFGLVTERVVSEPYTRSTTTGGFEILDDQSFNVLDRVYFQQFERPTAAISITFENDHNEYYVLATGKETDEYENNSIGRICIFQVTFERKLKLVHQFQTEGMVDSIRSFNGKLIASIHGM</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NTE1</accession>
    <name>A0A1C7NTE1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Peptidyl-prolyl cis-trans isomerase</fullName>
            <ecNumber evidence="12">5.2.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="primary">pin4</name>
        <name evidence="15" type="ORF">A0J61_01172</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 12">
            <text>[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)</text>
            <dbReference type="Rhea" id="RHEA:16237"/>
            <dbReference type="Rhea" id="RHEA-COMP:10747"/>
            <dbReference type="Rhea" id="RHEA-COMP:10748"/>
            <dbReference type="ChEBI" id="CHEBI:83833"/>
            <dbReference type="ChEBI" id="CHEBI:83834"/>
            <dbReference type="EC" id="5.2.1.8"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
            <location evidence="2">Cytoskeleton</location>
            <location evidence="2">Spindle</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="3">Nucleus</location>
            <location evidence="3">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the PpiC/parvulin rotamase family. PIN4 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.2.1.8" evidence="12"/>
    <dbReference type="EMBL" id="LUGH01000034">
        <property type="protein sequence ID" value="OBZ90764.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NTE1"/>
    <dbReference type="STRING" id="101091.A0A1C7NTE1"/>
    <dbReference type="InParanoid" id="A0A1C7NTE1"/>
    <dbReference type="OrthoDB" id="1911748at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005819">
        <property type="term" value="C:spindle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.50.40:FF:000015">
        <property type="entry name" value="Peptidyl-prolyl cis-trans isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.50.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043323">
        <property type="entry name" value="PIN4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046357">
        <property type="entry name" value="PPIase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000297">
        <property type="entry name" value="PPIase_PpiC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45995">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00639">
        <property type="entry name" value="Rotamase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54534">
        <property type="entry name" value="FKBP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50198">
        <property type="entry name" value="PPIC_PPIASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="7" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="9 11 12" id="KW-0413">Isomerase</keyword>
    <keyword evidence="10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 11 12" id="KW-0697">Rotamase</keyword>
    <feature type="domain" description="PpiC" evidence="14">
        <location>
            <begin position="28"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="13">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU363014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="OBZ90764.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="125" mass="13668" checksum="417B6D84FA922F7D" modified="2016-11-30" version="1">MAKGKQSGGKGKSAGGSKDESNSKLKPANAIKVRHILCEKHSRIMEALAKIKEENMRFDKVAELYSEDKAKAGGSLGWMNRGSMVGAFQDAAFALQPSTCDKPILTDPPIKTQFGYHLIMVEERK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NTM0</accession>
    <name>A0A1C7NTM0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_01109</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000032">
        <property type="protein sequence ID" value="OBZ90834.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NTM0"/>
    <dbReference type="InParanoid" id="A0A1C7NTM0"/>
    <dbReference type="OrthoDB" id="2239391at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ90834.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="94" mass="10724" checksum="24DED481535E55C9" modified="2016-11-30" version="1">MDSLFYLLFIDEFIVSSGITLQSIASSLALQANIPGEDIANMSDWSLPTTFENCYQRDHLSCFKFANILITPSFKIDIDIHLDDYTDVYFKSLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NWR6</accession>
    <name>A0A1C7NWR6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Male-enhanced antigen 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_00057</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000001">
        <property type="protein sequence ID" value="OBZ91894.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NWR6"/>
    <dbReference type="InParanoid" id="A0A1C7NWR6"/>
    <dbReference type="OrthoDB" id="5593200at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06910">
        <property type="entry name" value="MEA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="24"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="27"/>
            <end position="41"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ91894.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="127" mass="14989" checksum="52E20A1F2E664AA5" modified="2016-11-30" version="1">MNEIDEDFVEDFARQLDSIVRIQEQHQEEEDEEESFNEDTSEYQQIPQDEEDMYQQLMSEEEEIEEEVEVDLDAPLVIKVEPSNQLNSETSDLIRSIMSNIQLSNDAIPDWAKKIPEDAWLPRVKEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7LJI6</accession>
    <name>A0A1C7LJI6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">A0J61_11970</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the NGG1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01002793">
        <property type="protein sequence ID" value="OBZ63280.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7LJI6"/>
    <dbReference type="STRING" id="101091.A0A1C7LJI6"/>
    <dbReference type="InParanoid" id="A0A1C7LJI6"/>
    <dbReference type="OrthoDB" id="1232at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000124">
        <property type="term" value="C:SAGA complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003713">
        <property type="term" value="F:transcription coactivator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019340">
        <property type="entry name" value="Histone_AcTrfase_su3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13556:SF2">
        <property type="entry name" value="TRANSCRIPTIONAL ADAPTER 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13556">
        <property type="entry name" value="TRANSCRIPTIONAL ADAPTER 3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10198">
        <property type="entry name" value="Ada3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="247"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005330"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OBZ63280.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="247" mass="28544" checksum="4C1E2076B327B198" modified="2016-11-30" version="1" fragment="single">MLSIHLSSHLTIPPLTDLLNMKDGLESLLCLSERISSEFQRDLTIMDPSKDNLINQQTPKQEELISLCTLIGDRQITFESLSKKREGRVMSPIVKLRRLHDMPPLAITVGGRKNRPGERAEPVLPIQDEIPILTFWSTLDPYFRPLTEEDRAYLMATDQDPTDYNLASLDRYSHIAINDYGLTERVLNSLILDDMGWIKEEMKAIDTIEFEERLKQELVYVGLLEEEITEEDEISAEFRLILDELRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-06-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MU09</accession>
    <name>A0A1C7MU09_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_11631</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01002278">
        <property type="protein sequence ID" value="OBZ80320.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MU09"/>
    <dbReference type="InParanoid" id="A0A1C7MU09"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ80320.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="72" mass="7544" checksum="348B42364C1CB61E" modified="2016-11-30" version="1">MLVPSEATSEFAAIELVAFPEGVATMLTACVFSVAATAEFIKADTVGTLINGEHADKKDKIGAMVKLNVLFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-06-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MUF5</accession>
    <name>A0A1C7MUF5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_11500</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01002119">
        <property type="protein sequence ID" value="OBZ80452.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MUF5"/>
    <dbReference type="InParanoid" id="A0A1C7MUF5"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ80452.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="146" mass="16248" checksum="5BB65BB3B2B29B97" modified="2016-11-30" version="1">MLEHLGPVALSQMIFALERLEIDWRRTSYTKTPIEVRNSVCSSLRSLAENRNIPTSRCHNFWLEDAVLAYLYHNKARLIRPKCLESAAAAAATITTTTTTTFAVSATNTITTIDVFVVATTSIVTIDVFTVIATNTLTKKKVTYFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MV05</accession>
    <name>A0A1C7MV05_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">40S ribosomal protein S5</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">rps-5_1</name>
        <name evidence="6" type="ORF">A0J61_11288</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the universal ribosomal protein uS7 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001870">
        <property type="protein sequence ID" value="OBZ80663.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MV05"/>
    <dbReference type="FunCoup" id="A0A1C7MV05">
        <property type="interactions" value="596"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7MV05"/>
    <dbReference type="InParanoid" id="A0A1C7MV05"/>
    <dbReference type="OrthoDB" id="10264639at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015935">
        <property type="term" value="C:small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd14867">
        <property type="entry name" value="uS7_Eukaryote"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.455.10:FF:000002">
        <property type="entry name" value="40S ribosomal protein S5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.455.10">
        <property type="entry name" value="Ribosomal protein S7 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000235">
        <property type="entry name" value="Ribosomal_uS7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020606">
        <property type="entry name" value="Ribosomal_uS7_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023798">
        <property type="entry name" value="Ribosomal_uS7_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036823">
        <property type="entry name" value="Ribosomal_uS7_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005716">
        <property type="entry name" value="Ribosomal_uS7_euk/arc"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01028">
        <property type="entry name" value="uS7_euk_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11205">
        <property type="entry name" value="RIBOSOMAL PROTEIN S7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00177">
        <property type="entry name" value="Ribosomal_S7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002122">
        <property type="entry name" value="RPS7p_RPS7a_RPS5e_RPS7o"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47973">
        <property type="entry name" value="Ribosomal protein S7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00052">
        <property type="entry name" value="RIBOSOMAL_S7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 6" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Small ribosomal subunit protein uS7" evidence="5">
        <location>
            <begin position="44"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="180"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003619"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OBZ80663.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="180" mass="20002" checksum="2F4C3DBFA9C1DFBE" modified="2016-11-30" version="1" fragment="single">MPALGLPADVSATADGTRRLFNKWSYEDVEVKDISLQDYIQIRQQVYLPHTAGRFAVKRFRKAQCPIVERLTNALMMTGRNNGKKLMAARIVQHAFEIINLLTDANPLQILVDAIINCGPREDSTRIGSQGTVRRQAVDVSPLRRVNQAISLLTVGTRESAFRNVKTVAECLADELINAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MVQ6</accession>
    <name>A0A1C7MVQ6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Retrotransposon gag domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_11432</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01002030">
        <property type="protein sequence ID" value="OBZ80519.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7MVQ6"/>
    <dbReference type="InParanoid" id="A0A1C7MVQ6"/>
    <dbReference type="OrthoDB" id="2278008at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005162">
        <property type="entry name" value="Retrotrans_gag_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33223">
        <property type="entry name" value="CCHC-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33223:SF6">
        <property type="entry name" value="CCHC-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03732">
        <property type="entry name" value="Retrotrans_gag"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Retrotransposon gag" evidence="2">
        <location>
            <begin position="75"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="232"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="300"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="252"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="310"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="327"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="352"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="522"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03732"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ80519.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="522" mass="58485" checksum="84CC1FD3AED51E76" modified="2016-11-30" version="1" fragment="single">VHPAVIDFVNQLTRVLQSQTYDSSTSGLAKPPSIQLQRPKAYDSSRNVWKLDGWVRSIERLKEYYSWDDTQTFRFARTLLSGRAEAWFSLQETNVHGPVDWLSFKTLLINTFRPANAEDMVRDRLYSIKQSSSIQVYVDTFMDISMLLSASNLSPQQVMDRFLSDIFFRGXRDVELVQRIRGIHIEDRSLERVMREALDFEAAHNPSVHPTVYNNVDTVNTRRSFAAAGSVRDSHQTIDDPMDCDVLHSRSHQSGSLTSSNKDNRVSRGSSFTGNCHYCSRQGNTISECRTRAKDLANYESKMKDKYRNNKTSNNSGSNGPGRKSNLNAIDSNIAEPNSECSYSSTPHNKVTDSSSYLSTTSMSDNSHNEVIHSKHKCENKSDTQFTRLSSAVKMLGSQTDVHHLPTELVPIVASGTMKDSYSIDHKQTLNSSSFDLDVARIASLNTVVSCNLPLYHGIVTSSDGLPLDVHVLIDKGASENYISPRISKLIEGRHHHVRGREVETAGGNTSPITENVLFDLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MWP9</accession>
    <name>A0A1C7MWP9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_10719</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001339">
        <property type="protein sequence ID" value="OBZ81232.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MWP9"/>
    <dbReference type="STRING" id="101091.A0A1C7MWP9"/>
    <dbReference type="InParanoid" id="A0A1C7MWP9"/>
    <dbReference type="OrthoDB" id="5396806at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="165"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="450"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="530"/>
            <end position="632"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="54"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="113"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="188"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="209"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="240"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="264"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="453"/>
            <end position="491"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="493"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="532"/>
            <end position="541"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="552"/>
            <end position="593"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="604"/>
            <end position="632"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ81232.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="632" mass="69643" checksum="5CD06C00F71CBC32" modified="2016-11-30" version="1" fragment="single">APISSNSTTTKPATYDESSEDQPKTWASLLKSKPKPEEPAPTNTTNDTADHIDNSNNNTFTNEWDSSNTSTGNDWNATETTDGWNEPTVDEWSTPAHESKPVAAESHAKVDETPFEEEQETKEEEKHTEISAGANNNRLHNQEEPVVLPSSAAISSLDVKFGSLNVDDENATSEESTKEVTPVATEESVAQTANADTSAINNIPANDIPATTSVAPTSSSPVNTDATPAPTATSVTASNDTFAQSSGSYLKQQESSYTSQTNLPQQQQQQQQQQTHQQQQQQQQPQQPQQQQQPQQPQQQQPQQVPQHQQAPQQVPQQQFGMDHLTSAYSSYLPNQPPTGVAGFGMNPMGNLPDYGIYGSEAQRAAAMGYYDPTVFSHSPSVTSASVYQSRDKYSQDGLHGQSSQGANMPQQMYPTNLPYYQYYYMPNQFNAYQQSAYGQPFMNKSMYPSMYQQQQQQQQTQQQVQPQAAGKPSTTTGASAASPYGSAASPYGQPSQLYSSHQYDDLGMGLNDYQKSMYSQPQLQSFLGNLQQQPQQQQAQSKSANDLNARSAASTGANTSSAATGAAATPQQQPQQPQHHQQPQQQPYAANYFGQPQMFSYGQYPQHHQFQQMPPQQQQTQPTRQQQYWNQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MXB0</accession>
    <name>A0A1C7MXB0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">GATA-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">A0J61_10498</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001202">
        <property type="protein sequence ID" value="OBZ81452.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MXB0"/>
    <dbReference type="STRING" id="101091.A0A1C7MXB0"/>
    <dbReference type="InParanoid" id="A0A1C7MXB0"/>
    <dbReference type="OrthoDB" id="2162994at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00202">
        <property type="entry name" value="ZnF_GATA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.50.10">
        <property type="entry name" value="Erythroid Transcription Factor GATA-1, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051140">
        <property type="entry name" value="GATA_TF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000679">
        <property type="entry name" value="Znf_GATA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013088">
        <property type="entry name" value="Znf_NHR/GATA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45658">
        <property type="entry name" value="GATA TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45658:SF122">
        <property type="entry name" value="GATA ZINC FINGER DOMAIN-CONTAINING PROTEIN 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00320">
        <property type="entry name" value="GATA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00401">
        <property type="entry name" value="ZnF_GATA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57716">
        <property type="entry name" value="Glucocorticoid receptor-like (DNA-binding domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00344">
        <property type="entry name" value="GATA_ZN_FINGER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50114">
        <property type="entry name" value="GATA_ZN_FINGER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="GATA-type" evidence="6">
        <location>
            <begin position="195"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="46"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="251"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="46"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="251"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="289"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00094"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50114"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OBZ81452.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="289" mass="33772" checksum="20DCD2378AB726D3" modified="2016-11-30" version="1" fragment="single">YHNASPTPNQKQHYQHQYQLQHQYQLQHQYLKPYAHLPLRSEENQVYTNPPSFQKPKQQSSALPPLINRRPLAPHIVAQPPTNEEGDMLKLIIDQCTMIYQKVGKYRVDPLRESERNQIMDEVFGTTEVLLKSLKDLQARQQRHSVENDMQKPTFYEDDTNITHEATSEEYKMIRQARNLQESTRPKYRRRSKRSMVGQRCHSCNTSETPEWRRGPDGARTLCNACGLHYSKLLRKGSLTVQTHNYMLESASDSNRAQSMPYSIQQRTSSPHLPTEPTSLRITELKETE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MXH3</accession>
    <name>A0A1C7MXH3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Casein kinase II subunit alpha</fullName>
            <shortName evidence="10">CK II alpha</shortName>
            <ecNumber evidence="10">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">cka1_0</name>
        <name evidence="12" type="ORF">A0J61_10429</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Catalytic subunit of a constitutively active serine/threonine-protein kinase complex that phosphorylates a large number of substrates containing acidic residues C-terminal to the phosphorylated serine or threonine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="10">Heterotetramer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. CK2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="10"/>
    <dbReference type="EMBL" id="LUGH01001169">
        <property type="protein sequence ID" value="OBZ81523.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MXH3"/>
    <dbReference type="STRING" id="101091.A0A1C7MXH3"/>
    <dbReference type="InParanoid" id="A0A1C7MXH3"/>
    <dbReference type="OrthoDB" id="10254671at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005956">
        <property type="term" value="C:protein kinase CK2 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106310">
        <property type="term" value="F:protein serine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051726">
        <property type="term" value="P:regulation of cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd14132">
        <property type="entry name" value="STKc_CK2_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000059">
        <property type="entry name" value="Casein kinase II subunit alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000088">
        <property type="entry name" value="Casein kinase II subunit alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045216">
        <property type="entry name" value="CK2_alpha"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24054">
        <property type="entry name" value="CASEIN KINASE II SUBUNIT ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24054:SF0">
        <property type="entry name" value="CASEIN KINASE II SUBUNIT ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 10 12" id="KW-0418">Kinase</keyword>
    <keyword evidence="3 8 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 9" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="2 10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="11">
        <location>
            <begin position="84"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="119"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU000304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU369118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="OBZ81523.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="376" mass="44167" checksum="13E68AAB150BA854" modified="2016-11-30" version="1">MTRYSRKPANINKWGSIFLLSLVSVLTKTYLNRSNRITATQIVHDQTTILQPVEHPYAEVNRYMPSSYWDYESLQVNWSSPENYQMADEIGRGKYSEVFMGIDIRTNKKVAIKRLRPIKHLKIQREVKILEVVSGSINIITLLDVLKDPKTNTTSFVFEHVNSTNFRTLHPQLTDMDVRYYMYQLLKALDSCHSKGIMHRDIKPNNIMIDHQRRKLRLIDWGLAEFYHPEKTYNVRVASRSFKGPELLVGFKKYDYSLDLWSFGCVFAGVIFGVDPLFYGYDNTDQLVNIAHILGTDDLVDYTEKYEFDLDPYYVSTIQQHKRVPWSHFINSENTKYMSKEALDLLDRLLRYDHQERLTAKQAMAHPYFYPITASE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MXL7</accession>
    <name>A0A1C7MXL7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_10390</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001150">
        <property type="protein sequence ID" value="OBZ81560.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MXL7"/>
    <dbReference type="STRING" id="101091.A0A1C7MXL7"/>
    <dbReference type="InParanoid" id="A0A1C7MXL7"/>
    <dbReference type="OrthoDB" id="2256709at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="196"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="239"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="261"/>
            <end position="275"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ81560.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="281" mass="32229" checksum="B8D2EDE93E24A70A" modified="2016-11-30" version="1">MTPDEEMQQMRQQLAETQNMLSQLIEQHHLHPFGMRPRFDWAPDLLVQDQFALDRDLFNNEVLLDETRGELIDKYPPMRQLNYQPPPTMPEAKRRMNASQAKEDINFKHIQYLLSGTFRPLDILASEVCITDLPNDHPQRFIEIINDIRSLMLNINASISSSRTDIAFRDINPSFRAPSTNNQNYLMSSKAFQSAISQQSSSNKALKEASSRHRRSNGPASKPTARNNNPFFRDGSPIGQSGYNNNSDQSNNNGFSGGQRPSYQNTNPFIKTNRFNPKKKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-06-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MXQ1</accession>
    <name>A0A1C7MXQ1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_10333</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001122">
        <property type="protein sequence ID" value="OBZ81617.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MXQ1"/>
    <dbReference type="InParanoid" id="A0A1C7MXQ1"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ81617.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="79" mass="8792" checksum="F769081729D50A6A" modified="2016-11-30" version="1">MQTFIQEARLFMELNLKELLADVIDISPQDIELIMKKRKFSITVDYILATEKSVLAQIALVKSGGGVNDPCIAVITRLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-06-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MYD5</accession>
    <name>A0A1C7MYD5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_10105</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001034">
        <property type="protein sequence ID" value="OBZ81847.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MYD5"/>
    <dbReference type="InParanoid" id="A0A1C7MYD5"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ81847.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="103" mass="11539" checksum="53BB4A4FF59F5508" modified="2016-11-30" version="1">MDKAARNESWEGVTIDDSFVEDNSHSHRNSLTLLNHLFRIAPARPVSSLTEYMALIVSRNFRPLDSVSNRFLALPVISAPEEQETSVDSCIEIQVLPKVSSKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MYE2</accession>
    <name>A0A1C7MYE2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_10025</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001005">
        <property type="protein sequence ID" value="OBZ81925.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MYE2"/>
    <dbReference type="STRING" id="101091.A0A1C7MYE2"/>
    <dbReference type="InParanoid" id="A0A1C7MYE2"/>
    <dbReference type="OrthoDB" id="2385347at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd23767">
        <property type="entry name" value="IQCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.190">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000048">
        <property type="entry name" value="IQ_motif_EF-hand-BS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00612">
        <property type="entry name" value="IQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00015">
        <property type="entry name" value="IQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50096">
        <property type="entry name" value="IQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="392"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="402"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="440"/>
            <end position="452"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ81925.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="452" mass="52522" checksum="CC20A41CBECB2752" modified="2016-11-30" version="1">MLQQEFYNNQESHHYYDQDAITVTQHLTPEQYLYEFPTRDCLEALSYLDNDTQDSCFDLCSFVSSSAAFTSAYYNCYSIMDHEMEDELVDDGRLSPLQLPAQLVQSSRPVEPSSTLKPVGPSSFLADVQLCDHVTQTDVDSLDFDSSDSIISSTIRTLESRVVLIKLNRSQKQLTFIKTKQTDHDGSYSDEGYDDTTELDEELESNCIFYPIQENDDEQTKAAIRIQALWRGYCSRKQHKSNLKPDQQLLVQLMKFSNRVHHRQMQFMQDRLAHLEHQVRQESAMRTAFEKAMEDTVVLMDQQQKVIYDRLEQEVHLRQTYEAKVKTTLDQLQPLESRLRKETNARLRLEEMMTRVLDQMHASEESRKKQIQQDEASRCQLQAKLDQALSELDQLKRKDTSRPSNIPNTSSRRQPRSTITPTKTSPIERPSIVPSIRRSAVQQKSSTTNRRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MYW7</accession>
    <name>A0A1C7MYW7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_10353</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001131">
        <property type="protein sequence ID" value="OBZ81599.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MYW7"/>
    <dbReference type="STRING" id="101091.A0A1C7MYW7"/>
    <dbReference type="InParanoid" id="A0A1C7MYW7"/>
    <dbReference type="OrthoDB" id="2429120at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ81599.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="445" mass="50678" checksum="37528089FADD2E5D" modified="2016-11-30" version="1">MLPPGPLIESFINAAKEAKTIARMRDFVSQNFYTLQMENMTEQEKSDMIRDFKREAHSCGVEVCLLDIVWKQKGKRKADEIAVEVSESSRSKSRTTASSKSTGVSSFLSMLPSFEDQLKLNEKWMVDDTDVSSELALIRRKCIEKHRQGISMKSAESLTLGSIFFFSKDRNKSVTCFFNLATHKRILSSLDLKEKEYELPSVVDSWLTALKKEAKGDNLKTLRLMLRSLLNSREADDDDDLMLVASALFSLVPKHRTWSASCVVEDTFVKNQIADVIDVILGQSDDISMHYEWCNKKLSICVLKPDYTLSIEGRQAVNVEFFVVEVKTPSRNRNSNDFVKMGFILKFMLDNMVKHGMKKPKAFGLLVDGFNCYLYKMQLLYEAIYEMTEMESFALPRSADELPLLKDFLQSMLRVKAFASEAFEELESAAADADPQLLSRCRFAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MZ08</accession>
    <name>A0A1C7MZ08_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_09885</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000963">
        <property type="protein sequence ID" value="OBZ82063.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MZ08"/>
    <dbReference type="InParanoid" id="A0A1C7MZ08"/>
    <dbReference type="OrthoDB" id="2264251at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="108"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="125"/>
            <end position="137"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ82063.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="137" mass="15733" checksum="5CD68ED33B4783FA" modified="2016-11-30" version="1">MQVLPLLTPNQYNAKKRMRSTTDDFESHCFKKRLISTQTDFLPKPKLPLKDTLHMVDVNGTWLPMEQKAGSSRYTIPHFILSNSSSDYLPFTSGPLVLYQKHDSMPRITEITDNEDTDSLTSSESDNDDMFEPMDLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MZE8</accession>
    <name>A0A1C7MZE8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">MULE transposase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_09747</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000927">
        <property type="protein sequence ID" value="OBZ82203.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MZE8"/>
    <dbReference type="InParanoid" id="A0A1C7MZE8"/>
    <dbReference type="OrthoDB" id="2422867at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018289">
        <property type="entry name" value="MULE_transposase_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10551">
        <property type="entry name" value="MULE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008889383" description="MULE transposase domain-containing protein" evidence="1">
        <location>
            <begin position="18"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="domain" description="MULE transposase" evidence="2">
        <location>
            <begin position="34"/>
            <end position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF10551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ82203.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="95" mass="10681" checksum="B1B45F00B17FBD74" modified="2016-11-30" version="1">MTLLKFVVVGTVGAVASERDQKQHATIRFIGPRMRNETAGSYQWAMSQLNLIVWSSSTYTSQLPNNFVIDNDQVLMNAIENISPESKHILCVLQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MZV2</accession>
    <name>A0A1C7MZV2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 6">Autophagy-related protein 17</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">atg17</name>
        <name evidence="8" type="ORF">A0J61_09524</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Autophagy-specific protein that functions in response to autophagy-inducing signals as a scaffold to recruit other ATG proteins to organize preautophagosomal structure (PAS) formation. Modulates the timing and magnitude of the autophagy response, such as the size of the sequestering vesicles. Plays particularly a role in pexophagy and nucleophagy.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="6">Preautophagosomal structure membrane</location>
            <topology evidence="6">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the ATG17 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000869">
        <property type="protein sequence ID" value="OBZ82425.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MZV2"/>
    <dbReference type="FunCoup" id="A0A1C7MZV2">
        <property type="interactions" value="16"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7MZV2"/>
    <dbReference type="InParanoid" id="A0A1C7MZV2"/>
    <dbReference type="OrthoDB" id="1937984at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990316">
        <property type="term" value="C:Atg1/ULK1 kinase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034045">
        <property type="term" value="C:phagophore assembly site membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0060090">
        <property type="term" value="F:molecular adaptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030295">
        <property type="term" value="F:protein kinase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000045">
        <property type="term" value="P:autophagosome assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000422">
        <property type="term" value="P:autophagy of mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034727">
        <property type="term" value="P:piecemeal microautophagy of the nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007240">
        <property type="entry name" value="Atg17"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045326">
        <property type="entry name" value="ATG17-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28005">
        <property type="entry name" value="AUTOPHAGY-RELATED PROTEIN 17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28005:SF1">
        <property type="entry name" value="AUTOPHAGY-RELATED PROTEIN 17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04108">
        <property type="entry name" value="ATG17_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0072">Autophagy</keyword>
    <keyword evidence="3 6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Autophagy protein ATG17-like" evidence="7">
        <location>
            <begin position="16"/>
            <end position="392"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006259"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU368080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF04108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OBZ82425.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="457" mass="52839" checksum="ECA1510EA1E84701" modified="2016-11-30" version="1">MEQELIEFLLASKKALQTGQSICAQANTYLQTSESHVETIAKTHPKLVFVDNHILFQLSVLEKVREYLLTQSDDRKNRVKEHEAKLQSLTIELTNVFDLLKQCEVDPDILRVNQERKPTIDQQQYSCLFDYISDQEIIELQRQADDEIGEIETVSNSLKNQQKLLSAFISNTAKARIKALAISLDEPAAFYSGEKIQTQEEIISSMAEILTSLTNHYDQSSEAARIYQSDPDGRIDLDITVLRDDHEHIPTILEKLKSSLDAVESISEEIQGRMQMYLQVKNDMLKILNQLESFSAGGQADTILEKLTDADVEIKERELNLDDFFKQLSALAEWYRCYASSYNYLLLEIERRRKAEERQEAHRKELMKSFEDAYNDELQERRSWSAQHGQYLPEVLCPFINDSPSMLRVVIERESLTNQLPKLSMDNVQKVTTNNVNLYIQFTQDFFKALSEIHNSH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N067</accession>
    <name>A0A1C7N067_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_09886</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000963">
        <property type="protein sequence ID" value="OBZ82066.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N067"/>
    <dbReference type="STRING" id="101091.A0A1C7N067"/>
    <dbReference type="InParanoid" id="A0A1C7N067"/>
    <dbReference type="OrthoDB" id="2276327at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ82066.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="110" mass="12645" checksum="35BE51E3890210C1" modified="2016-11-30" version="1">MLPSILLKKEQGTVLSLLPKVHMLHHLAEDIFRFGLPIHYETEHGKQFNKFIREEILRTNRHNPSKDVATSFAKQFTIRHLINGGSFLVTTTGSDGTKETRRVMEVGYEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N0F6</accession>
    <name>A0A1C7N0F6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Endonuclease/exonuclease/phosphatase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_11117</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001689">
        <property type="protein sequence ID" value="OBZ80834.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N0F6"/>
    <dbReference type="InParanoid" id="A0A1C7N0F6"/>
    <dbReference type="OrthoDB" id="2282565at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.10.10">
        <property type="entry name" value="Endonuclease/exonuclease/phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036691">
        <property type="entry name" value="Endo/exonu/phosph_ase_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56219">
        <property type="entry name" value="DNase I-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ80834.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="367" mass="41650" checksum="17AC9375027C7507" modified="2016-11-30" version="1">MLSKTTADLPSTQSMLNTQFLPHSALWSKHCGIVSLNPSIFVTPYFITIDQRVIACHISHVNHLFPPTIVLVIYAPAQRVQREPFFESLLQLPLIQQYSPSSDDILSFNPDPALPPILILGNFNFQISNYQGKSYSDQPITLLPTYRLGNRKFTIDYIFASPALFNHLHSATVDFINSAWTDHAFLGCTFTFASQDQEPGLWRAHTNLAQNKYFKDTLITKLDQFHSLIQATSESATPQEQWDTVKDITKTLARQVGRRKAAAHLRLLSHLQRKRNKLLWDYKLTSILPLKLETTENQIGAMQQDRVDTLALRAGRHWRENGETSAGYLKSSITSRSIKHNISILNHPHTHQLCTSSRDMQSAATAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N0Q2</accession>
    <name>A0A1C7N0Q2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Esterase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">est_1</name>
        <name evidence="3" type="ORF">A0J61_09372</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000834">
        <property type="protein sequence ID" value="OBZ82578.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N0Q2"/>
    <dbReference type="FunCoup" id="A0A1C7N0Q2">
        <property type="interactions" value="18"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N0Q2"/>
    <dbReference type="InParanoid" id="A0A1C7N0Q2"/>
    <dbReference type="OrthoDB" id="408631at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013094">
        <property type="entry name" value="AB_hydrolase_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050300">
        <property type="entry name" value="GDXG_lipolytic_enzyme"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48081">
        <property type="entry name" value="AB HYDROLASE SUPERFAMILY PROTEIN C4A8.06C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48081:SF31">
        <property type="entry name" value="STERYL ACETYL HYDROLASE MUG81-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07859">
        <property type="entry name" value="Abhydrolase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Alpha/beta hydrolase fold-3" evidence="2">
        <location>
            <begin position="90"/>
            <end position="310"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07859"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ82578.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="337" mass="38523" checksum="F10238CAF1DB1A4A" modified="2016-11-30" version="1">MTSNHKVITSSRQVIGLLPYSIKRVILGRTFYFPLFISRRVLFFLTQPLASERRWIHKVIREDWKGVWITPHAKNATEAEKQATELDRIILYIHGGGFSLGYSTMYMSFFQQLIKSLHTQFKLSTAILSVEYSLCPEHRWPTACHECVNAYRYLVHEVGISPSKIVVIGDSAGGNLALTTLLSIRDLKRERQEKKEKDLPPLPLPSKVALLSPWVDLSLRQYPKRPDCILPDLIEMYVRNYVVDMTEASLKHPLVSPTYASLDQLDSTQWLICYGQHEILGPSIESFIDKVKGHKYDVTVSECDGEGHASFVHTMMSSSPVAYERDVRVLVNWISNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N0W9</accession>
    <name>A0A1C7N0W9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Inhibitor I9 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_09226</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the protease inhibitor I9 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000803">
        <property type="protein sequence ID" value="OBZ82723.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N0W9"/>
    <dbReference type="STRING" id="101091.A0A1C7N0W9"/>
    <dbReference type="InParanoid" id="A0A1C7N0W9"/>
    <dbReference type="OrthoDB" id="5518345at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004866">
        <property type="term" value="F:endopeptidase inhibitor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042144">
        <property type="term" value="P:vacuole fusion, non-autophagic"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.80:FF:000005">
        <property type="entry name" value="Proteinase inhibitor I2B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.80">
        <property type="entry name" value="Peptidase S8 propeptide/proteinase inhibitor I9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052471">
        <property type="entry name" value="PBI_I9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010259">
        <property type="entry name" value="S8pro/Inhibitor_I9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037045">
        <property type="entry name" value="S8pro/Inhibitor_I9_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28288">
        <property type="entry name" value="PROTEASE B INHIBITOR 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28288:SF2">
        <property type="entry name" value="PROTEASE B INHIBITOR 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05922">
        <property type="entry name" value="Inhibitor_I9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54897">
        <property type="entry name" value="Protease propeptides/inhibitors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Inhibitor I9" evidence="2">
        <location>
            <begin position="4"/>
            <end position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00038069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF05922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ82723.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="81" mass="8825" checksum="87FFEAADC47027A1" modified="2016-11-30" version="1">MSSQYIVTFKRDTPSEIIEQKIKEVEASGATITHRYDSAIKGFSVAVPDDAVNTLSFEHEHITGVEADGEVTTQGKSLLKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N0X7</accession>
    <name>A0A1C7N0X7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_10957</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001538">
        <property type="protein sequence ID" value="OBZ80994.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="InParanoid" id="A0A1C7N0X7"/>
    <dbReference type="OrthoDB" id="10044727at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ80994.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="96" mass="10845" checksum="56582FBC62F6111E" modified="2016-11-30" version="1">MEVYXRNXEEEALEPILQXGEKKMVLVTHDESTFYANDARKERWVEQGEASIAPKGQGKSIMVSRFMCACHGTIKGVIEGEEISSRTLFFPGGDEW</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-06-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N1F0</accession>
    <name>A0A1C7N1F0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_08985</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000748">
        <property type="protein sequence ID" value="OBZ82965.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N1F0"/>
    <dbReference type="InParanoid" id="A0A1C7N1F0"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ82965.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="96" mass="10723" checksum="ECC4333B6FD94D51" modified="2016-11-30" version="1">MYRSHISQLQDSLAFSTAALADDLMDSLKQSPLAKSSSLGCLLFEVYQSLFPKLPALKQYLMASFLGAFTLLHGCFNTVGRLETSVIDQYRYQALH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N316</accession>
    <name>A0A1C7N316_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Large ribosomal subunit protein mL54</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">mrpl37</name>
        <name evidence="9" type="ORF">A0J61_08461</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the mitochondrion-specific ribosomal protein mL54 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000653">
        <property type="protein sequence ID" value="OBZ83492.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N316"/>
    <dbReference type="FunCoup" id="A0A1C7N316">
        <property type="interactions" value="38"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N316"/>
    <dbReference type="InParanoid" id="A0A1C7N316"/>
    <dbReference type="OrthoDB" id="10252718at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005762">
        <property type="term" value="C:mitochondrial large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013870">
        <property type="entry name" value="Ribosomal_mL54"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28595">
        <property type="entry name" value="39S RIBOSOMAL PROTEIN L54, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28595:SF1">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN ML54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08561">
        <property type="entry name" value="Ribosomal_L37"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 9" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="2" id="KW-0809">Transit peptide</keyword>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="85"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="102"/>
            <end position="117"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00033752"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00035179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OBZ83492.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="117" mass="13517" checksum="DA8B51103A8A9487" modified="2016-11-30" version="1">MLSTIVRSSRPIYQPTLVRASYLHTTLLARNTADATTTTTRKPSAAPKGTVLKGLQYIKDKPEPVALDDSEYPDWLWDLLDEKKQKQKTTKPVNRQYHRKQNRDAIKAMNFMKDKKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N318</accession>
    <name>A0A1C7N318_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Transcription factor atf21</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">atf21</name>
        <name evidence="9" type="ORF">A0J61_08429</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000647">
        <property type="protein sequence ID" value="OBZ83525.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N318"/>
    <dbReference type="STRING" id="101091.A0A1C7N318"/>
    <dbReference type="InParanoid" id="A0A1C7N318"/>
    <dbReference type="OrthoDB" id="295274at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd14687">
        <property type="entry name" value="bZIP_ATF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.170">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004827">
        <property type="entry name" value="bZIP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046347">
        <property type="entry name" value="bZIP_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051027">
        <property type="entry name" value="bZIP_transcription_factors"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002112">
        <property type="entry name" value="Leuzip_Jun"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19304">
        <property type="entry name" value="CYCLIC-AMP RESPONSE ELEMENT BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00170">
        <property type="entry name" value="bZIP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00043">
        <property type="entry name" value="LEUZIPPRJUN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00338">
        <property type="entry name" value="BRLZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57959">
        <property type="entry name" value="Leucine zipper domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50217">
        <property type="entry name" value="BZIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00036">
        <property type="entry name" value="BZIP_BASIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="BZIP" evidence="8">
        <location>
            <begin position="107"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="68"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="195"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="132"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="7">
        <location>
            <begin position="93"/>
            <end position="103"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OBZ83525.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="216" mass="24653" checksum="2EE8F965D358F961" modified="2016-11-30" version="1">MFKVNTYQPTSDTLTPTKLLMNPAANDWNFHHKSNSMADFNPYMSEINPFDTNTNDLFDQKFQQAVPSMMMMPPPSPEEDSSNHSLELTRPMASPPSSPPTTDTPPKKQRKKLLEKNREAAYRCRQKKKKWIHDLEEKSVVVESKNKELQEQVSQLREESIYLRNLLLTHGNCNCKVVQAYLRRTSEQLSSSMSNTGLTQLANSPTCSSGHENFGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N364</accession>
    <name>A0A1C7N364_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Cytosolic Fe-S cluster assembly factor CFD1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">CFD1</name>
        <name evidence="13" type="ORF">A0J61_08412</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery. Required for maturation of extramitochondrial Fe-S proteins. The NBP35-CFD1 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins.</text>
    </comment>
    <comment type="function">
        <text evidence="10">Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery. Required for maturation of extramitochondrial Fe-S proteins. The NUBP1-NUBP2 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins. Negatively regulates cilium formation and structure.</text>
    </comment>
    <comment type="subunit">
        <text evidence="11">Heterotetramer of 2 NUBP1 and 2 NUBP2 chains. Interacts with KIFC1. Interacts with NUBP1.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
            <location evidence="2">Cytoskeleton</location>
            <location evidence="2">Cilium axoneme</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
            <location evidence="1">Microtubule organizing center</location>
            <location evidence="1">Centrosome</location>
            <location evidence="1">Centriole</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="12">Belongs to the Mrp/NBP35 ATP-binding proteins family. NUBP2/CFD1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000644">
        <property type="protein sequence ID" value="OBZ83540.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N364"/>
    <dbReference type="STRING" id="101091.A0A1C7N364"/>
    <dbReference type="InParanoid" id="A0A1C7N364"/>
    <dbReference type="OrthoDB" id="1741334at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005930">
        <property type="term" value="C:axoneme"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005814">
        <property type="term" value="C:centriole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:1904564">
        <property type="term" value="C:cytosolic [4Fe-4S] assembly scaffold complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140663">
        <property type="term" value="F:ATP-dependent FeS chaperone activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016226">
        <property type="term" value="P:iron-sulfur cluster assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002098">
        <property type="term" value="P:tRNA wobble uridine modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd02037">
        <property type="entry name" value="Mrp_NBP35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000796">
        <property type="entry name" value="Cytosolic Fe-S cluster assembly factor NUBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02040">
        <property type="entry name" value="Mrp_NBP35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03039">
        <property type="entry name" value="NUBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000808">
        <property type="entry name" value="Mrp-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019591">
        <property type="entry name" value="Mrp/NBP35_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028600">
        <property type="entry name" value="NUBP2/Cfd1_eukaryotes"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033756">
        <property type="entry name" value="YlxH/NBP35"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23264:SF19">
        <property type="entry name" value="CYTOSOLIC FE-S CLUSTER ASSEMBLY FACTOR NUBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23264">
        <property type="entry name" value="NUCLEOTIDE-BINDING PROTEIN NBP35 YEAST -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10609">
        <property type="entry name" value="ParA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01215">
        <property type="entry name" value="MRP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 12" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="7 12" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 12" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8 12" id="KW-0408">Iron</keyword>
    <keyword evidence="9 12" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="5 12" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 12" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="12">
        <location>
            <begin position="18"/>
            <end position="25"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="192"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="195"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004114"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004430"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00053368"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00065349"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03039"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="OBZ83540.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="266" mass="28919" checksum="E675BE86DA6E3BD8" modified="2016-11-30" version="1">MSEANLAGIKHIVLVLSGKGGVGKSSVTTQLALALVHQGKKVGVLDIDLTGPSIPRMLGLDGKQVHQASQGWVPVYADENKRLACMSIGFLLSNKNDSVVWRGPKKNAMIKQFLQDVCWGELDYLLVDTPPGTSDEHIGIVEYLREFNPDGAVIVTTPQGVAIADVRKELSFCKKVKLPILGVVENMSGFVCPHCAECTNIFSSGGGESMAQEYGIEFFGRVPIDPGFTQMVDAEGEGSYIHLFEKSNLFPLFQQICHKVVEKVNQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N3C7</accession>
    <name>A0A1C7N3C7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_08371</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000637">
        <property type="protein sequence ID" value="OBZ83581.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N3C7"/>
    <dbReference type="InParanoid" id="A0A1C7N3C7"/>
    <dbReference type="OrthoDB" id="2259910at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="170"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="288"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="296"/>
            <end position="314"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ83581.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="314" mass="35526" checksum="07019884B79A02B9" modified="2016-11-30" version="1">MIYLLPYLVQQEPIREDNEEENDEAQIESVEEEDLDKCGLISNQHCREDGLCEYCAMCLRDSCITDANTCSEATTNKTNLYDWFDDCLIDESSSSKNLCATNVECFQYYKTSGRPSTYTLHSLTCNPSNCMLIRNKNHLLPEPKPLPPVKSPETHSQPRKIDRHQTKEHGLVIVASCCTTCVLFIAIFFWFCRKKRWLPFQKTKQECCESISSIPNSAPPSFRTIPSCAGDRASCRSSQTLPVYVSACHPPPKYEQAIVTQIRDQPENVVIHHYAHYDPVMCPSWSPSSSGLSSSQNRTENSFSDIPANIQTSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N3D8</accession>
    <name>A0A1C7N3D8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Nicotinamide riboside kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">nrk1</name>
        <name evidence="2" type="ORF">A0J61_08790</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000712">
        <property type="protein sequence ID" value="OBZ83159.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N3D8"/>
    <dbReference type="FunCoup" id="A0A1C7N3D8">
        <property type="interactions" value="280"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N3D8"/>
    <dbReference type="InParanoid" id="A0A1C7N3D8"/>
    <dbReference type="OrthoDB" id="10041966at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02024">
        <property type="entry name" value="NRK1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006083">
        <property type="entry name" value="PRK/URK"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10285">
        <property type="entry name" value="URIDINE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00485">
        <property type="entry name" value="PRK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Phosphoribulokinase/uridine kinase" evidence="1">
        <location>
            <begin position="22"/>
            <end position="168"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ83159.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="246" mass="28248" checksum="23D5EE7B2D8B13D0" modified="2016-11-30" version="1">MVNVVTIGIGLQVTSETDVDVVRGPSCSGKTTATRILRQILTHSVVIYQDDFYKASLKPEDKVPLHPETQYGNWDCPESVDFDRMAAMIDYVRTHQGCLPEDYDSNEENNVHDGSSLVSESTLASLKELLAPFMKDHVFVFVDGFMLYYDDKVASQLNLKFQFTSDYQIVKERREKRQGYHTVEGYWVDPPGYFDKVVWPEHLRLTQYYHQSIQGLHQIDTAKYSIDQTALRVAHIIRDNTQCVSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N3G2</accession>
    <name>A0A1C7N3G2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulatory protein rxt2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">rtx2</name>
        <name evidence="3" type="ORF">A0J61_08296</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000625">
        <property type="protein sequence ID" value="OBZ83653.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N3G2"/>
    <dbReference type="InParanoid" id="A0A1C7N3G2"/>
    <dbReference type="OrthoDB" id="2405722at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013904">
        <property type="entry name" value="RXT2_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08595">
        <property type="entry name" value="RXT2_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Transcriptional regulatory protein RXT2 N-terminal" evidence="2">
        <location>
            <begin position="69"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="204"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="204"/>
            <end position="216"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF08595"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ83653.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="307" mass="35569" checksum="5EBEBF40FFB3E330" modified="2016-11-30" version="1">MSQPLSTDALPPANKWIQPDNDESDSDQKWATQELGGNKLRAPKTLAEEEEFSKFGKKRAIVKRKRKRSEDGISDEEEDPYTLINIEDILSPIELPTDIVRRPALRRILLSTQIDALAKTSMEFIENEKNFNKILCRLSSIMHQDDPRYLNLTFERTVEERQKYQQEQEAAREAALSSHISSDAVDALDPRRLDADVESSIHKERIVSEQQKKVPNEDDDEEHVEQEQVVVVVEEQEEEGDVEARDVVKRVKELLLENINYSNEYIARLQGARNKLCKASMQKETLWKELKASAREEDMRNKATYHH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N3Y3</accession>
    <name>A0A1C7N3Y3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">PDZ domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">A0J61_08583</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S1C family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000675">
        <property type="protein sequence ID" value="OBZ83366.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="FunCoup" id="A0A1C7N3Y3">
        <property type="interactions" value="45"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N3Y3"/>
    <dbReference type="InParanoid" id="A0A1C7N3Y3"/>
    <dbReference type="OrthoDB" id="4217619at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006915">
        <property type="term" value="P:apoptotic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034605">
        <property type="term" value="P:cellular response to heat"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0120174">
        <property type="term" value="P:stress-induced homeostatically regulated protein degradation pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd06786">
        <property type="entry name" value="cpPDZ1_ScNma111-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd06719">
        <property type="entry name" value="PDZ2-4_Nma111p-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.42.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.120">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001478">
        <property type="entry name" value="PDZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025926">
        <property type="entry name" value="PDZ-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036034">
        <property type="entry name" value="PDZ_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009003">
        <property type="entry name" value="Peptidase_S1_PA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001940">
        <property type="entry name" value="Peptidase_S1C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46366">
        <property type="entry name" value="PRO-APOPTOTIC SERINE PROTEASE NMA111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46366:SF8">
        <property type="entry name" value="PRO-APOPTOTIC SERINE PROTEASE NMA111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12812">
        <property type="entry name" value="PDZ_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13365">
        <property type="entry name" value="Trypsin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00834">
        <property type="entry name" value="PROTEASES2C"/>
    </dbReference>
    <dbReference type="SMART" id="SM00228">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50156">
        <property type="entry name" value="PDZ domain-like"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50494">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="PDZ" evidence="4">
        <location>
            <begin position="300"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="domain" description="PDZ" evidence="4">
        <location>
            <begin position="780"/>
            <end position="849"/>
        </location>
    </feature>
    <feature type="domain" description="PDZ" evidence="4">
        <location>
            <begin position="871"/>
            <end position="952"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010541"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00228"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OBZ83366.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="986" mass="109461" checksum="9E5A5C3FEB1A5C77" modified="2016-11-30" version="1">MSNTPLSPEKQSMPLLPKDHNFEGGDSPASNMGSYPSKRRKLDADSMEEDDGVNGYISEGFPIAPELKPSKWQGTINTVVKAIVSIRFSQVAAFDTEGPETSEASGFIVDAQNGIILTNRHVACAGPFVGEAICHDHEEVDVFPIYRDPVHDFGFLKFDPTKIKYMPLTQVELHPELAKVGLDIRVVGNDAGEKLSILAGSISRLDRNTPEYGDLTYNDFNTFYLQAASSTSGGSSGSPVIDIDGNAVALQAGGHTKAATDFFLPLDRVKRALEFIQRGESVPRGDIQTQFMYRPFDEARRLGLQPETEERLRTLFPDEIGLLVVETVLPEGPAHRKLEEGDILLTMDGEYITKFVPFESVLDSNVGKEIKVGIERGGQPMELLIQVGDLHAITPDRYVEIGGSKLNEVSYQLARAYCVPCRGVYVSEPSGMFRLDGPDNGWIVKSVDDKETPTLNTFVEXMQSIPDRARVPVVYYSIADTHTIMVAVVQVERHWSSFRLAVRNDATGLWDFTNLGDPLPPKPIEPSTKHFVQLDDSLGPAKDLIRCLVKVNYYMPCRLDGFPRSRKQGAGIIVDKENGFVVVSRSIVPTAMGDLTLNVADSLVIPAKVLFLHPTHNFTIVQYNPKLLDKTDVMSAPFSEKTLSQGHKVTLVAHNHNQRPVCLSTVVTDITCITIPHNGTPRFRSINMDAITLDTPLALQCSSGLLADADGLVQGLWMNFLGERNMNGHDNEYHLGIHITTVRPILDRLKAGERHLVLRSINAELMPVQMAQATAMGLSDHWIHQVEQANPAKHQLFMVRRTEAGCESSKVLKELDLILAVNGQVITRMYEMDIQYTSESLQMTILRGKKEMIVDVRTSPVSGEGTDRVIFWAGAVLHEPHKAVLQQSKTLPSRIYISARSKGSPAYMYGLVPTMWITHINGQQVVTLDDLVTAVKHIEDNTYVRVRCVSFDNVPIMLSVKMVNHYFPLEDMIRDPKAECGWSKKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N422</accession>
    <name>A0A1C7N422_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Acetolactate synthase small subunit, mitochondrial</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">ILV6_0</name>
        <name evidence="8" type="ORF">A0J61_08140</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Amino-acid biosynthesis; L-isoleucine biosynthesis; L-isoleucine from 2-oxobutanoate: step 1/4.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2">Amino-acid biosynthesis; L-valine biosynthesis; L-valine from pyruvate: step 1/4.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the acetolactate synthase small subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000600">
        <property type="protein sequence ID" value="OBZ83811.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N422"/>
    <dbReference type="FunCoup" id="A0A1C7N422">
        <property type="interactions" value="127"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N422"/>
    <dbReference type="InParanoid" id="A0A1C7N422"/>
    <dbReference type="OrthoDB" id="2013116at2759"/>
    <dbReference type="UniPathway" id="UPA00047">
        <property type="reaction ID" value="UER00055"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00049">
        <property type="reaction ID" value="UER00059"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005948">
        <property type="term" value="C:acetolactate synthase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042645">
        <property type="term" value="C:mitochondrial nucleoid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990610">
        <property type="term" value="F:acetolactate synthase regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009097">
        <property type="term" value="P:isoleucine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009099">
        <property type="term" value="P:L-valine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd04878">
        <property type="entry name" value="ACT_AHAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.260:FF:000001">
        <property type="entry name" value="Acetolactate synthase, small subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.260">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1150">
        <property type="entry name" value="ACT-like. Chain A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004789">
        <property type="entry name" value="Acetalactate_synth_ssu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027271">
        <property type="entry name" value="Acetolactate_synth/TF_NikR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019455">
        <property type="entry name" value="Acetolactate_synth_ssu_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045865">
        <property type="entry name" value="ACT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002912">
        <property type="entry name" value="ACT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039557">
        <property type="entry name" value="AHAS_ACT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054480">
        <property type="entry name" value="AHAS_small-like_ACT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053050">
        <property type="entry name" value="ALS_regulatory_subunit"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00119">
        <property type="entry name" value="acolac_sm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31242">
        <property type="entry name" value="ACETOLACTATE SYNTHASE SMALL SUBUNIT, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31242:SF2">
        <property type="entry name" value="ACETOLACTATE SYNTHASE SMALL SUBUNIT, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22629">
        <property type="entry name" value="ACT_AHAS_ss"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10369">
        <property type="entry name" value="ALS_ss_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55021">
        <property type="entry name" value="ACT-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51671">
        <property type="entry name" value="ACT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="5" id="KW-0100">Branched-chain amino acid biosynthesis</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ACT" evidence="7">
        <location>
            <begin position="70"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="281"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="289"/>
            <end position="298"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005025"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006341"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51671"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OBZ83811.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="306" mass="34230" checksum="0E46C58C29591086" modified="2016-11-30" version="1">MLRFIQRQLVNPSTTPVRALSTSGLAFKKHLRQKKIGPAPAYSPSSIEDAVYNIIYNTPEEEAQRPTRHVLNCLAENEPGVISRISGILASRNFNIESMVAAHTEVEGLSRMTIVFKGKESQIEQARRQLEDLVPVWAVLDYSRTKIIERELLMIKVSILGPEHLHEQLPTAKLDENTVEYVDEKLNDSMTNDVTESDKPPSVALRETFSHLRAITELSRLFEGKIVDVSSDSVIVQICAKPERITSFMRLCKPFGIIEAARTGVMAMPRSPVHDYYGAQTEHAYSSETAEEDDDDVVDPTSLPPG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N455</accession>
    <name>A0A1C7N455_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">U2 snRNP-associated SURP motif-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">U2surp</name>
        <name evidence="7" type="ORF">A0J61_08048</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000586">
        <property type="protein sequence ID" value="OBZ83902.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N455"/>
    <dbReference type="STRING" id="101091.A0A1C7N455"/>
    <dbReference type="InParanoid" id="A0A1C7N455"/>
    <dbReference type="OrthoDB" id="377209at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006396">
        <property type="term" value="P:RNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12223">
        <property type="entry name" value="RRM_SR140"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.790">
        <property type="entry name" value="Surp module"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006569">
        <property type="entry name" value="CID_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008942">
        <property type="entry name" value="ENTH_VHS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051485">
        <property type="entry name" value="SR-CTD_assoc_factor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035009">
        <property type="entry name" value="SR140_RRM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000061">
        <property type="entry name" value="Surp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035967">
        <property type="entry name" value="SWAP/Surp_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23140">
        <property type="entry name" value="RNA PROCESSING PROTEIN LD23810P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23140:SF0">
        <property type="entry name" value="U2 SNRNP-ASSOCIATED SURP MOTIF-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04818">
        <property type="entry name" value="CID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01805">
        <property type="entry name" value="Surp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00582">
        <property type="entry name" value="RPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00648">
        <property type="entry name" value="SWAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48464">
        <property type="entry name" value="ENTH/VHS domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109905">
        <property type="entry name" value="Surp module (SWAP domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51391">
        <property type="entry name" value="CID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50128">
        <property type="entry name" value="SURP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="4">
        <location>
            <begin position="202"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="domain" description="SURP motif" evidence="5">
        <location>
            <begin position="341"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="domain" description="CID" evidence="6">
        <location>
            <begin position="447"/>
            <end position="592"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="173"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="596"/>
            <end position="664"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="601"/>
            <end position="656"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51391"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OBZ83902.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="664" mass="75327" checksum="1894384EDBE853FB" modified="2016-11-30" version="1">MSEKRKREETSEEEEEEEFQRPIKPIPASKLQAFTIGSHKKTAFQRHKEEADLKKQQENLEAAKVYAEFVASFEEPKPYQLGTTSFVKSGTLMPKDPVDQYHNQTPAVPSTFKPMPFVKAGESPMQSTLKVKHKLESLDDEDDALAKLKSIPKAQKKRNLDSFLEEIKKGQEVRTRNDNKHGTAPIEGDTIGSFDEGNPNTTNLYVGNINPTTTEAGLCQEFGKFGPIASVKIMWPRTQEEKDKGNNCGFVSFMTRKDAAEAIRGLDGKELHGFTLRVGWGKAVPLPATPFFVLDKKVSLGQAKTGLPFNAQIYPGPPGVNSRPRAEVHVTKPVDVKLMRVMHRMIERVLKHGPLFEAIIMDKELNNPTFKFLFDNSSPEHIYYRWRLYSLSQGDTKSRWRDEPFQMFEGGPWWIPPELPLLDKETEPMFDTDDELADQDNVAKGTLGQIAKQRLGGLIREVTFQRGTIARAMSFAIDHSDAASEVVDVLSKSILIPDIPFSVKLARLYLVSDILHNSSVHVSNAWKYRKEFEAHLPVIFDHFNSIYRSINARLKAEQVRKYISSIIHVWENWMIFPKYYTDQLSDIFLKKEKASSITQPEDVDGEPIEDVDGEPMEDVDGEPIEDVDGEPMDDVDGEPMEDADGEPIQDNEEEDFTQVNDMFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N4G8</accession>
    <name>A0A1C7N4G8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 7">Protein phosphatase PP2A regulatory subunit B</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">pab1_2</name>
        <name evidence="8" type="ORF">A0J61_07999</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Phosphatase 2A affects a variety of biological processes in the cell such as transcription, cell cycle progression and cellular morphogenesis, and provides an initial identification of critical substrates for this phosphatase. The regulatory subunit may direct the catalytic subunit to distinct, albeit overlapping, subsets of substrates.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the phosphatase 2A regulatory subunit B family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000579">
        <property type="protein sequence ID" value="OBZ83951.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N4G8"/>
    <dbReference type="FunCoup" id="A0A1C7N4G8">
        <property type="interactions" value="430"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N4G8"/>
    <dbReference type="InParanoid" id="A0A1C7N4G8"/>
    <dbReference type="OrthoDB" id="6274823at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000159">
        <property type="term" value="C:protein phosphatase type 2A complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019888">
        <property type="term" value="F:protein phosphatase regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010972">
        <property type="term" value="P:negative regulation of G2/M transition of mitotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902531">
        <property type="term" value="P:regulation of intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.10:FF:000189">
        <property type="entry name" value="Protein phosphatase PP2A regulatory subunit B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000009">
        <property type="entry name" value="PP2A_PR55"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018067">
        <property type="entry name" value="PP2A_PR55_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11871">
        <property type="entry name" value="PROTEIN PHOSPHATASE PP2A REGULATORY SUBUNIT B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037309">
        <property type="entry name" value="PP2A_PR55"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00600">
        <property type="entry name" value="PP2APR55"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01024">
        <property type="entry name" value="PR55_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01025">
        <property type="entry name" value="PR55_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 7" id="KW-0853">WD repeat</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008259"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00055525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00067298"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU331113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OBZ83951.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="427" mass="48637" checksum="357CF7E36D01306D" modified="2016-11-30" version="1">MSEEEKRWKFAQCFGDKGDSDDITEADIISAVEFDHTGNYLATGDKGGRVVLFERNDGKKGCEYKFYTEFQSHEPEFDYLKSLEIEEKINKIKWCRRTNSAHFLLSTNDKTIKLWKVFERNVKIPTSNNITSGGLSIPKFSQQDNLVAAVPKKIYANAHAYHINSISVNSDAETYISADDLRINLWNLNISEQSFNIVDIKPANMEELTEVITAAEFHPQQCNLLMYSSSKGTVKLADMRQSALCDQNAKVFEAYEDPNSRSFFSEIISSISDVKFSPDGRYILARDYLTLKIWDINMESKPVQTINVNDNLRSSLCDLYENDCIFDKFECMFSGDGKSVMTGSYSNNFSIYNRETNNEIPLQADKSVFKSKRLGPAAKNKLTLGRNGKRDDMEVIDFNKKILHASWHPRDNVIAVAATNNLFIFAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N4J5</accession>
    <name>A0A1C7N4J5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">EamA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_07968</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000573">
        <property type="protein sequence ID" value="OBZ83981.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N4J5"/>
    <dbReference type="STRING" id="101091.A0A1C7N4J5"/>
    <dbReference type="InParanoid" id="A0A1C7N4J5"/>
    <dbReference type="OrthoDB" id="10062838at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037185">
        <property type="entry name" value="EmrE-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026505">
        <property type="entry name" value="Solute_c_fam_35_mem_F3/F4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19346">
        <property type="entry name" value="SUGAR PHOSPHATE TRANSPORTER DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19346:SF4">
        <property type="entry name" value="SUGAR PHOSPHATE TRANSPORTER DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103481">
        <property type="entry name" value="Multidrug resistance efflux transporter EmrE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="29"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="63"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="114"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="146"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="173"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="212"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="241"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="280"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="308"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="334"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ83981.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="369" mass="41304" checksum="A33701DB5285F14D" modified="2016-11-30" version="1">MASYHTLPTDEQPPRSPTIQYRHKQSRSVLATAMLTICIITFVLQTELAQYVQKTTQYSKPYFILYISHSCYVFMIPIQILAEYTQLPHKTLSTALHDLIQYRVQGNHTDPMQFVIKTSLWLSVLLTLPAYIWYLSVNLTSMSSLTAIYNTGCFFAYLFSILMLKDKLRLTKICAVLLCLIGVLTMACWPLPSEDSDIKQAQKDKIAEWMGILVASIGAALYGFYEVYYKKYASPSQPTVLFANTLTGTIGLITLLVLWIPFPILHMLNIETFELPDLETFGYILAIASMSVIYNATFMAVIALVNPVFAAVGVMLTIPAVAVTDVLITGVMVPLPTIFGSLFILVGFVILNKQVGIEEKIDQEMSIEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N5M7</accession>
    <name>A0A1C7N5M7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_07638</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000527">
        <property type="protein sequence ID" value="OBZ84311.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N5M7"/>
    <dbReference type="InParanoid" id="A0A1C7N5M7"/>
    <dbReference type="OrthoDB" id="10463826at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ84311.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="74" mass="8508" checksum="F2D04F9E85AF0870" modified="2016-11-30" version="1">MEASIAPYSRQYRLDISHTALGIQRLSLSVGNCRYTCVSNFYDETSATVQKYRLHLCPYMADYAMSLIYPSRES</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N5R0</accession>
    <name>A0A1C7N5R0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Palmitoyltransferase PFA4</fullName>
            <ecNumber evidence="11">2.3.1.225</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">Protein S-acyltransferase</fullName>
            <shortName evidence="11">PAT</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11">Protein fatty acyltransferase 4</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="15" type="primary">PFA4_1</name>
        <name evidence="11" type="synonym">PFA4</name>
        <name evidence="15" type="ORF">A0J61_07599</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Mediates the reversible addition of palmitate to target proteins, thereby regulating their membrane association and biological function.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>L-cysteinyl-[protein] + hexadecanoyl-CoA = S-hexadecanoyl-L-cysteinyl-[protein] + CoA</text>
            <dbReference type="Rhea" id="RHEA:36683"/>
            <dbReference type="Rhea" id="RHEA-COMP:10131"/>
            <dbReference type="Rhea" id="RHEA-COMP:11032"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57379"/>
            <dbReference type="ChEBI" id="CHEBI:74151"/>
            <dbReference type="EC" id="2.3.1.225"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="11">Endoplasmic reticulum membrane</location>
            <topology evidence="11">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="11 12">The DHHC domain is required for palmitoyltransferase activity.</text>
    </comment>
    <comment type="similarity">
        <text evidence="11">Belongs to the DHHC palmitoyltransferase family. PFA4 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.225" evidence="11"/>
    <dbReference type="EMBL" id="LUGH01000521">
        <property type="protein sequence ID" value="OBZ84351.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N5R0"/>
    <dbReference type="InParanoid" id="A0A1C7N5R0"/>
    <dbReference type="OrthoDB" id="331948at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019706">
        <property type="term" value="F:protein-cysteine S-palmitoyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03199">
        <property type="entry name" value="DHHC_PAT_PFA4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001594">
        <property type="entry name" value="Palmitoyltrfase_DHHC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033682">
        <property type="entry name" value="PFA4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039859">
        <property type="entry name" value="PFA4/ZDH16/20/ERF2-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12246">
        <property type="entry name" value="PALMITOYLTRANSFERASE ZDHHC16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01529">
        <property type="entry name" value="DHHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50216">
        <property type="entry name" value="DHHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 11 12" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="4 11" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="8 11" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="6 11 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 11" id="KW-0564">Palmitate</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 11 12" id="KW-0808">Transferase</keyword>
    <keyword evidence="3 11 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 11 12" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11 12">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11 12">
        <location>
            <begin position="41"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11 12">
        <location>
            <begin position="143"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11 12">
        <location>
            <begin position="183"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="domain" description="Palmitoyltransferase DHHC" evidence="14">
        <location>
            <begin position="94"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="363"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="364"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="13">
        <location>
            <begin position="393"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="active site" description="S-palmitoyl cysteine intermediate" evidence="11">
        <location>
            <position position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00048048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU079119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF01529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="OBZ84351.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="403" mass="46743" checksum="ACEEE8B13BD43E05" modified="2016-11-30" version="1">MLELIPGKVFVAGVVLLICTIAYSSQLVLFLPAYGWWTTQSVINLVPYNLLVIMVFYNYYLCVYTDPGKIPTNWEPPSSLVAAKEITSEGITGPRYCKTCRVYKPPRSHHCRYCKRCVLKMDHHCPWIDNCVGYQNHGHFIRFIVYAVTACXYTIGLLVGRVRDIMEAIRRFEFNAEPSTMEIIFMILNFVLAFVVAFCVGILMMYQLYCVSRNQSNIESWERSKVEKLMQRGKIMPIQYPFDIGFYRNLCEVLGPHPLTWFWPKQMHGDGLSFPIVMGTDPSIPYFWPPRDPDDLRPSIFSSKYRRQQEMQRLLAENPDAIFEEDESEGYYDSGSFASDSEHDEEQGMRRFVNQSVLDLSGASHHDYNRRTYHHTEQSDSEEDKIPLSVLTVKKKMSSSKED</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N6H0</accession>
    <name>A0A1C7N6H0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">HPP transmembrane region domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_07321</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000487">
        <property type="protein sequence ID" value="OBZ84631.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N6H0"/>
    <dbReference type="STRING" id="101091.A0A1C7N6H0"/>
    <dbReference type="InParanoid" id="A0A1C7N6H0"/>
    <dbReference type="OrthoDB" id="2016548at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007065">
        <property type="entry name" value="HPP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058581">
        <property type="entry name" value="TM_HPP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33741">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN DDB_G0269096-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33741:SF5">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN DDB_G0269096-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04982">
        <property type="entry name" value="TM_HPP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="33"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="63"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="93"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="169"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="domain" description="HPP transmembrane region" evidence="2">
        <location>
            <begin position="31"/>
            <end position="197"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ84631.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="339" mass="37630" checksum="12BFF62B33B9DFF8" modified="2016-11-30" version="1">MSRTLEKIPYFISHFLGYRRPDHKSRTLAVWRIYLWSFLAAWIGIAVLEIVFAYGPSFTEHQAPIIIASFGATAVLVYGVIDSPLAQPRNVIGGHIVGALSGAIISQLFLGIKQTWESESQRLAVQWVGGATAMALSLNIMQITKTVHPPGGATALIAVVTPSIIQIRWFYIGIVALSSVLQVVVACLINNIERKYPLYWWTPEKLPLKVDPTTFSTVIPTHGTRRHEDTVFDNLTNVEEGRLQEGQYDDDKDDSSSHEVVEGIAVTETRSSSATALGHAHTVHKALSALQENASTWNDRDNQYILLTTKNQIFMSPQIQLTQNEKAILDSLINKLQQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N6J3</accession>
    <name>A0A1C7N6J3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_07288</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000484">
        <property type="protein sequence ID" value="OBZ84667.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N6J3"/>
    <dbReference type="InParanoid" id="A0A1C7N6J3"/>
    <dbReference type="OrthoDB" id="426882at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="81"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="170"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="83"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="100"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="118"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="170"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="180"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="205"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="220"/>
            <end position="234"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ84667.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="291" mass="32896" checksum="08CD1D122B78CCE9" modified="2016-11-30" version="1">MSSSIDNPYAITDTTTVKSILENIANEKNWSKEDVTNDLSILARNRIHHVHDLRALSSESWAQIELLPLVKDLLRNAIDSDWPKNNTCNSSKQVEDQLSEYEKKKDKKKKDEEDEAKKKKKDKKKKGGSLLGSPVEPAILTHHSVSNGYLHDNSSDTSLISQDPITIENTIRNANVGNTSEEEDNESDESEEYNTPTTPARRKSVSFSNETSIINDITKKEKKKDKKNKKKKKEKGLVNPSLAYPYTHRPIVNIHHQPSRNYQTLPPVPPDDSFLQSIHDKLVSSSTTVDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N7B1</accession>
    <name>A0A1C7N7B1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_06993</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000450">
        <property type="protein sequence ID" value="OBZ84961.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N7B1"/>
    <dbReference type="InParanoid" id="A0A1C7N7B1"/>
    <dbReference type="OrthoDB" id="2264193at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ84961.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="142" mass="16141" checksum="DB442AF60773A68B" modified="2016-11-30" version="1">MPKTVRFDPIDTVIITYSAEEYDRSYFVSAVPVTYSFRPVVSDVTMNTPVLSTTTQPSHHTGRPSIKPLDLSIVPNSHRRALESPIQPEVDSINDKKTKRPKLSINTQSLTPLFFSELSTHYKCKNEDEEEEHGFLIPVMAY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N859</accession>
    <name>A0A1C7N859_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_06641</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000411">
        <property type="protein sequence ID" value="OBZ85315.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N859"/>
    <dbReference type="STRING" id="101091.A0A1C7N859"/>
    <dbReference type="InParanoid" id="A0A1C7N859"/>
    <dbReference type="OrthoDB" id="2384350at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="26"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="74"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="26"/>
            <end position="36"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ85315.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="94" mass="10689" checksum="596D5CE52CB7BC9D" modified="2016-11-30" version="1">MPGPVTFFSLGAAGATAYYVNRRNSMTSDVDNSNMTPHKYARRRSSTVIPDHDWPSHKQAEYLWRRDNGVSFSHNSAPKYPQGFQPKDLKQTSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N8J7</accession>
    <name>A0A1C7N8J7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Transmembrane 9 superfamily member</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">A0J61_06549</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the nonaspanin (TM9SF) (TC 9.A.2) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000400">
        <property type="protein sequence ID" value="OBZ85401.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N8J7"/>
    <dbReference type="STRING" id="101091.A0A1C7N8J7"/>
    <dbReference type="InParanoid" id="A0A1C7N8J7"/>
    <dbReference type="OrthoDB" id="1666796at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072657">
        <property type="term" value="P:protein localization to membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007034">
        <property type="term" value="P:vacuolar transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004240">
        <property type="entry name" value="EMP70"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10766:SF111">
        <property type="entry name" value="TRANSMEMBRANE 9 SUPERFAMILY MEMBER 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10766">
        <property type="entry name" value="TRANSMEMBRANE 9 SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02990">
        <property type="entry name" value="EMP70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="6"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="34"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="73"/>
            <end position="94"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005227"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU363079"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OBZ85401.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="104" mass="12019" checksum="06A3DE3FFBD23FA7" modified="2016-11-30" version="1">MVFVVLILTCSQVTILMCYFHLCSEDYHWSWRAFLTSAATGFYVFMYSVLYYFTKLDINSFTSTVLYFGYSSVISFLISVFTGAVGYLSCLYFLQKIFASIKVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N8R0</accession>
    <name>A0A1C7N8R0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">BAG family molecular chaperone regulator 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">Bag1_0</name>
        <name evidence="5" type="ORF">A0J61_06426</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000387">
        <property type="protein sequence ID" value="OBZ85525.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N8R0"/>
    <dbReference type="FunCoup" id="A0A1C7N8R0">
        <property type="interactions" value="229"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N8R0"/>
    <dbReference type="InParanoid" id="A0A1C7N8R0"/>
    <dbReference type="OrthoDB" id="417450at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000774">
        <property type="term" value="F:adenyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051087">
        <property type="term" value="F:protein-folding chaperone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050821">
        <property type="term" value="P:protein stabilization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.120">
        <property type="entry name" value="BAG domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039773">
        <property type="entry name" value="BAG_chaperone_regulator"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036533">
        <property type="entry name" value="BAG_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003103">
        <property type="entry name" value="BAG_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000626">
        <property type="entry name" value="Ubiquitin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12329:SF16">
        <property type="entry name" value="BAG FAMILY MOLECULAR CHAPERONE REGULATOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12329">
        <property type="entry name" value="BCL2-ASSOCIATED ATHANOGENE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02179">
        <property type="entry name" value="BAG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63491">
        <property type="entry name" value="BAG domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51035">
        <property type="entry name" value="BAG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50053">
        <property type="entry name" value="UBIQUITIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0143">Chaperone</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ubiquitin-like" evidence="3">
        <location>
            <begin position="61"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="domain" description="BAG" evidence="4">
        <location>
            <begin position="180"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="18"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OBZ85525.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="235" mass="26275" checksum="3A038C5894B38945" modified="2016-11-30" version="1">MHSLASFLGLNKKDAQPRPSNNHNTQPTPQRDLRDTVVVAYDNRYYDVHFRDVRGGIRFATVGMLKQRCKQVTGVTIATMKLKVSGAYIKDDTATLPSSGIHEGSVVFVLGERANREQLEQTTSGNPEEAGYMTRISNLMQKVNQSREQIETLDIQVVAAIEHTLDDKGLKETEDLGIFLSEVLMQALIGLDSVECPPEFETARAKRREGVKQCQALMDRVDQSRSALKQAIQQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N923</accession>
    <name>A0A1C7N923_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Calmodulin-4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">CAM4_1</name>
        <name evidence="5" type="ORF">A0J61_06365</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000381">
        <property type="protein sequence ID" value="OBZ85591.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N923"/>
    <dbReference type="STRING" id="101091.A0A1C7N923"/>
    <dbReference type="InParanoid" id="A0A1C7N923"/>
    <dbReference type="OrthoDB" id="26525at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016460">
        <property type="term" value="C:myosin II complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00051">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.238.10:FF:000181">
        <property type="entry name" value="CALML5 isoform 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.238.10:FF:000251">
        <property type="entry name" value="Calmodulin-related protein 97A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003299">
        <property type="entry name" value="Calflagin-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050230">
        <property type="entry name" value="CALM/Myosin/TropC-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23048:SF0">
        <property type="entry name" value="CALMODULIN LIKE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23048">
        <property type="entry name" value="MYOSIN LIGHT CHAIN 1, 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13499">
        <property type="entry name" value="EF-hand_7"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01362">
        <property type="entry name" value="CALFLAGIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00054">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0106">Calcium</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="EF-hand" evidence="4">
        <location>
            <begin position="8"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="4">
        <location>
            <begin position="44"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="4">
        <location>
            <begin position="80"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="4">
        <location>
            <begin position="116"/>
            <end position="147"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OBZ85591.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="147" mass="16268" checksum="339078D33572C273" modified="2016-11-30" version="1">MSDQLSPEEIAEYQEAFQLFDTDGDGSITAKELGTVLRKFGMNPSEGELQDMVNDVDADGNGNIDFNEFLGLVKHMKNGNEGDDLKEAFKVFDVDGNGLIDREELRKVMASLNESLSEEELEAMIKEADTNGDGQISFEEFKIMMGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N935</accession>
    <name>A0A1C7N935_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Pleckstrin homology domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">A0J61_08101</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000594">
        <property type="protein sequence ID" value="OBZ83854.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N935"/>
    <dbReference type="STRING" id="101091.A0A1C7N935"/>
    <dbReference type="InParanoid" id="A0A1C7N935"/>
    <dbReference type="OrthoDB" id="2149224at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005938">
        <property type="term" value="C:cell cortex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005543">
        <property type="term" value="F:phospholipid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015631">
        <property type="term" value="F:tubulin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032065">
        <property type="term" value="P:maintenance of protein location in cell cortex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000226">
        <property type="term" value="P:microtubule cytoskeleton organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053005">
        <property type="entry name" value="Nuclear_Pos-Cytoskel_Interact"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024774">
        <property type="entry name" value="PH_dom-Mcp5-type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28190">
        <property type="entry name" value="NUCLEAR MIGRATION PROTEIN NUM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28190:SF1">
        <property type="entry name" value="NUCLEAR MIGRATION PROTEIN NUM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12814">
        <property type="entry name" value="Mcp5_PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="571"/>
            <end position="590"/>
        </location>
    </feature>
    <feature type="domain" description="Pleckstrin homology" evidence="4">
        <location>
            <begin position="506"/>
            <end position="568"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="214"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="101"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="257"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="217"/>
            <end position="231"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF12814"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OBZ83854.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="633" mass="72775" checksum="17F225A528722A00" modified="2016-11-30" version="1">MLHTTSFLGYESPELSELYTNKTSTEYTCVGEAPVTFRRLTPRPVRKQAFQEHSLQTPDSLLMQGDAALASLKVEIADKQQEITYLMNSKAKAEGKYKDEIWSLELEKQDLLQRINDLTNNLVKSNLDLARLEQQEKSLFNELEHLKMLRDEEMNETKIKHEQEVMAYKEMLLVQRTEKERALKELQRLNQKPQLRSNSVILRPISQRTNDCRHADSASIASAASPPQSRSMFAVGQSQSVNKKDESLEMKSLRISLDQAHDIIKSMQDRINKETEERTKTDKLLREAQEMAEHFRNSKNRQTAFDSNNRSLKSVVGQEHLQRKKSKKIMVSEQIPISLLSEELERCQKQPTVDSFSSLKSQKEMKKQALEGEEMLGRHFLCTGLQQVCTSSIGLKPNVATSTICQTSPHLYQARNPPILLRLRELDSFTNSPTTYFADKTNENVKRDTMSFLEGSLKKENDLKSFAFSDKKNNQQSSNAPVVDFNTQVSLDLLLKPLSKDQIQEVLAALTRCIIGEWVWKYTRKVVGVGFSEKKHRRFFWINPYTRVLHWSTHKPGSSAQAHSKSGKESFHLSVILVVLFIILFHVAFVESFRIICDNKKASTVPYLLIKTSERNVKIQCLDLDCHYSWVKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N9S7</accession>
    <name>A0A1C7N9S7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Hsp70 nucleotide exchange factor FES1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">FES1</name>
        <name evidence="4" type="ORF">A0J61_06257</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the FES1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000369">
        <property type="protein sequence ID" value="OBZ85698.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N9S7"/>
    <dbReference type="FunCoup" id="A0A1C7N9S7">
        <property type="interactions" value="401"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N9S7"/>
    <dbReference type="InParanoid" id="A0A1C7N9S7"/>
    <dbReference type="OrthoDB" id="10250458at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000774">
        <property type="term" value="F:adenyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000357">
        <property type="entry name" value="HEAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050693">
        <property type="entry name" value="Hsp70_NEF-Inhibitors"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013918">
        <property type="entry name" value="Nucleotide_exch_fac_Fes1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19316:SF18">
        <property type="entry name" value="HSP70-BINDING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19316">
        <property type="entry name" value="PROTEIN FOLDING REGULATOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08609">
        <property type="entry name" value="Fes1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02985">
        <property type="entry name" value="HEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Nucleotide exchange factor Fes1" evidence="3">
        <location>
            <begin position="1"/>
            <end position="90"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011045"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF08609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OBZ85698.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="294" mass="32827" checksum="AC84851EF52D4AB5" modified="2016-11-30" version="1">MEKLLQWAVNNSDQNSLSEQAAAIRRGEAQPDPAKYDPKILEAILGKDDATRMKESVECINNPEDTVDNKVIALDNLEMLIEGIDNARNIENMKLWPGIIKQLSAAEPEVRKGTAWVCGTAVQNNPEAQKAFLDNEGLAPLVQLLKDQDSSVRSKAIYAISCFLKHNPVGVQSFDQLEGLSVLQTLLKQSDDTTALRKIVFLYNSLIFENESVLKRAVENDTMRDLDAILVKYTTKESEDEDMVEKTLRTLHTLITKGGLSVPDELKQHIKAACTQFGLENLALVESEYQELIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NB08</accession>
    <name>A0A1C7NB08_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">60S ribosomal protein L34-B</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">RPL34B_2</name>
        <name evidence="5" type="synonym">RPL34B_0</name>
        <name evidence="4" type="synonym">RPL34B_1</name>
        <name evidence="6" type="ORF">A0J61_06001</name>
        <name evidence="5" type="ORF">A0J61_09192</name>
        <name evidence="4" type="ORF">A0J61_10532</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the eukaryotic ribosomal protein eL34 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001220">
        <property type="protein sequence ID" value="OBZ81419.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="LUGH01000794">
        <property type="protein sequence ID" value="OBZ82757.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="LUGH01000343">
        <property type="protein sequence ID" value="OBZ85939.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NB08"/>
    <dbReference type="FunCoup" id="A0A1C7NB08">
        <property type="interactions" value="491"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NB08"/>
    <dbReference type="InParanoid" id="A0A1C7NB08"/>
    <dbReference type="OrthoDB" id="277449at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.20.340.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.20.370.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008195">
        <property type="entry name" value="Ribosomal_eL34"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038562">
        <property type="entry name" value="Ribosomal_eL34_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018065">
        <property type="entry name" value="Ribosomal_eL34_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46595">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L34"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01199">
        <property type="entry name" value="Ribosomal_L34e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01250">
        <property type="entry name" value="RIBOSOMALL34"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01145">
        <property type="entry name" value="RIBOSOMAL_L34E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 6" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009875"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OBZ81419.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OBZ82757.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OBZ85939.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="109" mass="12393" checksum="8401B93C19B92F35" modified="2016-11-30" version="1">MAQRLTYRRRLSYNTRSNRVKAVKTPGGNLVYQYQKKPVKAPRCGDCGETLAGIKALRAREFATVSKTNKHVSRAYGGSRCAHCVRNRIVRAFLIEEQKIVKKVLKAQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NBA4</accession>
    <name>A0A1C7NBA4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_07316</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000487">
        <property type="protein sequence ID" value="OBZ84624.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NBA4"/>
    <dbReference type="InParanoid" id="A0A1C7NBA4"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="71"/>
            <end position="91"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ84624.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="97" mass="10903" checksum="12B8B376942121FD" modified="2016-11-30" version="1">MGLDIKQGLVGTYITHLSPKWSDHAILFATAQLGSSKLKGGLWRATPAYITNYSIETALTILHHAGIEIPFLTFILILLLFFHICHILFVFSPFNEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NC14</accession>
    <name>A0A1C7NC14_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Putative 12-oxophytodienoate reductase 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">OPR2</name>
        <name evidence="5" type="ORF">A0J61_07047</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the NADH:flavin oxidoreductase/NADH oxidase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000457">
        <property type="protein sequence ID" value="OBZ84894.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NC14"/>
    <dbReference type="FunCoup" id="A0A1C7NC14">
        <property type="interactions" value="288"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NC14"/>
    <dbReference type="InParanoid" id="A0A1C7NC14"/>
    <dbReference type="OrthoDB" id="276546at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016628">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd02933">
        <property type="entry name" value="OYE_like_FMN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.70:FF:000059">
        <property type="entry name" value="N-ethylmaleimide reductase, FMN-linked"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001155">
        <property type="entry name" value="OxRdtase_FMN_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045247">
        <property type="entry name" value="Oye-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22893">
        <property type="entry name" value="NADH OXIDOREDUCTASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22893:SF91">
        <property type="entry name" value="NADPH DEHYDROGENASE 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00724">
        <property type="entry name" value="Oxidored_FMN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51395">
        <property type="entry name" value="FMN-linked oxidoreductases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NADH:flavin oxidoreductase/NADH oxidase N-terminal" evidence="4">
        <location>
            <begin position="7"/>
            <end position="341"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00724"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OBZ84894.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="368" mass="41409" checksum="50FBA8C79C11D6E1" modified="2016-11-30" version="1">MTVKNALFSPTKVGNLELKHRVVLCPLTRYRATKEAVPTDLQVEYYKQRASEGGLLITEATFISPSAGSYPQAPGIFTDEQIEGWKKVTKAVHEKKAYIYLQLWHIGRAGSHLLNPNHEATVSASAIPIKGKDMLGNDFETPRPLEVNEIKSIVEDYRQASLNAIKAGFDGVEIHSANGYLLDQFLNSNSNKRTDEYGGSVENRCRFTLEVVDAVADAIGAERTGIRFSPGGSFQDMADENPTETWGHALTQLQKKHPNLSYVHVTEPRSSWLTDNNTERTDSLDSFRKIWQGAFITASGFSNRKEQAFEIAERTGNLCAFGRAFIANPDLPERLRNGWELNKYDRSTFYTHDAKGYIDYPFYNDKQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NC69</accession>
    <name>A0A1C7NC69_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Disintegrin and metalloproteinase domain-containing protein B</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">ADM-B_2</name>
        <name evidence="9" type="ORF">A0J61_05247</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Probable zinc protease.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000278">
        <property type="protein sequence ID" value="OBZ86712.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NC69"/>
    <dbReference type="FunCoup" id="A0A1C7NC69">
        <property type="interactions" value="49"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NC69"/>
    <dbReference type="InParanoid" id="A0A1C7NC69"/>
    <dbReference type="OrthoDB" id="5951731at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007229">
        <property type="term" value="P:integrin-mediated signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="4.10.70.10:FF:000003">
        <property type="entry name" value="Disintegrin and metalloproteinase domain-containing protein 17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.390.10">
        <property type="entry name" value="Collagenase (Catalytic Domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.70.10">
        <property type="entry name" value="Disintegrin domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006586">
        <property type="entry name" value="ADAM_Cys-rich"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001762">
        <property type="entry name" value="Disintegrin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036436">
        <property type="entry name" value="Disintegrin_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024079">
        <property type="entry name" value="MetalloPept_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001590">
        <property type="entry name" value="Peptidase_M12B"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11905">
        <property type="entry name" value="ADAM A DISINTEGRIN AND METALLOPROTEASE DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11905:SF159">
        <property type="entry name" value="ADAM METALLOPROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00200">
        <property type="entry name" value="Disintegrin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13688">
        <property type="entry name" value="Reprolysin_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00608">
        <property type="entry name" value="ACR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00050">
        <property type="entry name" value="DISIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57552">
        <property type="entry name" value="Blood coagulation inhibitor (disintegrin)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55486">
        <property type="entry name" value="Metalloproteases ('zincins'), catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50215">
        <property type="entry name" value="ADAM_MEPRO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50214">
        <property type="entry name" value="DISINTEGRIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 4" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="9" id="KW-0401">Integrin</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="680"/>
            <end position="699"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M12B" evidence="8">
        <location>
            <begin position="265"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="domain" description="Disintegrin" evidence="7">
        <location>
            <begin position="500"/>
            <end position="585"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="751"/>
            <end position="776"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="791"/>
            <end position="835"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="794"/>
            <end position="803"/>
        </location>
    </feature>
    <feature type="active site" evidence="4">
        <location>
            <position position="418"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="417"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="421"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="427"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="disulfide bond" evidence="4">
        <location>
            <begin position="436"/>
            <end position="441"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00056552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00074021"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00276"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50214"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50215"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OBZ86712.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="835" mass="91868" checksum="ACB9ABB29072B73F" modified="2016-11-30" version="1">MKLICRSVNNKQLLWVEPIQSVKLDIAKRSDLFFEKREISPNYHFQPTRPQSLQFDDSFRLSIDAYNKTFYLHLTPNYDLFHPQAVIHQQGKSVRMNPSDYRVYRGHVVDPIYSQHYWLAGIDEDMQDKPGVLGWARIIVRNDIEHHLDHPLFEGAFTLYGDTYHVKLKENYHLTKRSDDAELAEQHVDAYMVTYRDSDTAEATQHNLSTQSNGCGFDKITHTTQKRYSPLEIDYDPLKIDYTPFGSVGKTLAKRAPTGCPTTKKILYMGVAADCTYVKYYQNADNARMQIINDWNSVSNVYDSTFNVAIGLINITIMDSTCPSSPASSTNWNQACSTSYSISSRLSDFSRWRGTIGDDGAGLWHLMTNCATGQEVGIAWMSQVCNTGSVFSSSSNQYTSGTGVSSIIRDEWKVIAHEVGHGFGAIHDCTSQNCPCSGSSCQCCPYSSTQCDAGGRYFMNPTSNASSDAFSPCSITTICTDMPNYTSCLQDPGSRNITTLQMCGNGIKETGEDCDTGGKDSNCCDPSTCKFKSGAVCDDFNDLCCNNCQLRPANYTCRPASGECDVAEVCSGTSGDCPADKYKDDLTSCSNGMQCASGQCTSRDAQCVARGTTNNIKKSCSADSGCAMSCQNPSSSFSCIIFPGNFMDGTPCGVGGVCKSGSCDQSNFGNNAVNWINSHLYIVIPIAAVIGLIFLFCLFRCCCYSYSDGYNNLGKTTIYTVPAQQAVYPTQYSTTPQPYYPQQPYYPNNNGWVDPTLYNGPPGPRGYPQQPLPAYSQATPQHDAYELNNANNWQNQPTSQTPAPTSPAPNYSRVPNPPSQGNTAMANRPHNEGVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NC89</accession>
    <name>A0A1C7NC89_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_05268</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000280">
        <property type="protein sequence ID" value="OBZ86691.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NC89"/>
    <dbReference type="InParanoid" id="A0A1C7NC89"/>
    <dbReference type="OrthoDB" id="2251104at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="49"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="60"/>
            <end position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ86691.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="73" mass="7895" checksum="2BDBCFC3603F803C" modified="2016-11-30" version="1">MKNDPEHPTKEPFTSPEHSKTNGSDVLFKAVSVPFAALGGFVDQVSRKATQIISPEDQKPTPTTDNPTPTTTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7ND16</accession>
    <name>A0A1C7ND16_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Expansin-YoaJ</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">yoaJ_1</name>
        <name evidence="5" type="ORF">A0J61_05036</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000261">
        <property type="protein sequence ID" value="OBZ86918.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7ND16"/>
    <dbReference type="STRING" id="101091.A0A1C7ND16"/>
    <dbReference type="InParanoid" id="A0A1C7ND16"/>
    <dbReference type="OrthoDB" id="406505at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd22272">
        <property type="entry name" value="DPBB_EXLX1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.40.10">
        <property type="entry name" value="RlpA-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051477">
        <property type="entry name" value="Expansin_CellWall"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009009">
        <property type="entry name" value="RlpA-like_DPBB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036908">
        <property type="entry name" value="RlpA-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31836">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31836:SF21">
        <property type="entry name" value="EXPANSIN-LIKE PROTEIN 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03330">
        <property type="entry name" value="DPBB_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50685">
        <property type="entry name" value="Barwin-like endoglucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008889628" evidence="3">
        <location>
            <begin position="26"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="domain" description="RlpA-like protein double-psi beta-barrel" evidence="4">
        <location>
            <begin position="163"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="68"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="68"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF03330"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OBZ86918.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="249" mass="27734" checksum="222C4569218D5933" modified="2016-11-30" version="1">MRLTHSSLFALTTVITSSLLYQVQSAPLNEVDTVADKDHVVVAFDVQSQNQHNGLNEWTQHLDKRCGHSHVAARRRTHKKKTTRRKSHKKKKVIKKKTTHKKKTTKRKTTKRKTTKRKTTHKKKTTKRKTTKRKTTKKTVKKTSSSSGEKFSGDGTYYTPGLGSCGITNTESEMVAAMNAPQMNNGANPNLNPLCGKYITVKGPKGSVRVKIVDTCPPCAKGDIDLSVGAFGKVGSYIDGRIPITWEWS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2024-05-29" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7ND43</accession>
    <name>A0A1C7ND43_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_05080</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000264">
        <property type="protein sequence ID" value="OBZ86880.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7ND43"/>
    <dbReference type="InParanoid" id="A0A1C7ND43"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ86880.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="77" mass="8602" checksum="6BCC62E75646840B" modified="2016-11-30" version="1" fragment="single">STGEHHAPPLPLYLISSETCLTKCTWRLSSTMLHPLAFLQSQVFTKALLSFSPFLYSIYDLPSLLCPQFLSDTLSPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7ND80</accession>
    <name>A0A1C7ND80_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex</fullName>
            <ecNumber evidence="9">2.3.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">Dbt_1</name>
        <name evidence="12" type="ORF">A0J61_04927</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 9">
            <name>(R)-lipoate</name>
            <dbReference type="ChEBI" id="CHEBI:83088"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion matrix</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 9">Belongs to the 2-oxoacid dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.-" evidence="9"/>
    <dbReference type="EMBL" id="LUGH01000252">
        <property type="protein sequence ID" value="OBZ87025.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7ND80"/>
    <dbReference type="STRING" id="101091.A0A1C7ND80"/>
    <dbReference type="InParanoid" id="A0A1C7ND80"/>
    <dbReference type="OrthoDB" id="15567at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016407">
        <property type="term" value="F:acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031405">
        <property type="term" value="F:lipoic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045333">
        <property type="term" value="P:cellular respiration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd06849">
        <property type="entry name" value="lipoyl_domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.100:FF:000013">
        <property type="entry name" value="Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.559.10:FF:000007">
        <property type="entry name" value="Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.10">
        <property type="entry name" value="Chloramphenicol acetyltransferase-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.320.10">
        <property type="entry name" value="E3-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003016">
        <property type="entry name" value="2-oxoA_DH_lipoyl-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001078">
        <property type="entry name" value="2-oxoacid_DH_actylTfrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050743">
        <property type="entry name" value="2-oxoacid_DH_E2_comp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000089">
        <property type="entry name" value="Biotin_lipoyl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023213">
        <property type="entry name" value="CAT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036625">
        <property type="entry name" value="E3-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004167">
        <property type="entry name" value="PSBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011053">
        <property type="entry name" value="Single_hybrid_motif"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43178">
        <property type="entry name" value="DIHYDROLIPOAMIDE ACETYLTRANSFERASE COMPONENT OF PYRUVATE DEHYDROGENASE COMPLEX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43178:SF5">
        <property type="entry name" value="LIPOAMIDE ACYLTRANSFERASE COMPONENT OF BRANCHED-CHAIN ALPHA-KETO ACID DEHYDROGENASE COMPLEX, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00198">
        <property type="entry name" value="2-oxoacid_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00364">
        <property type="entry name" value="Biotin_lipoyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02817">
        <property type="entry name" value="E3_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52777">
        <property type="entry name" value="CoA-dependent acyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47005">
        <property type="entry name" value="Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51230">
        <property type="entry name" value="Single hybrid motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50968">
        <property type="entry name" value="BIOTINYL_LIPOYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00189">
        <property type="entry name" value="LIPOYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51826">
        <property type="entry name" value="PSBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9 12" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="5 9" id="KW-0450">Lipoyl</keyword>
    <keyword evidence="7" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9 12" id="KW-0808">Transferase</keyword>
    <keyword evidence="6" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="Lipoyl-binding" evidence="10">
        <location>
            <begin position="23"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="domain" description="Peripheral subunit-binding (PSBD)" evidence="11">
        <location>
            <begin position="130"/>
            <end position="167"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001938"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004305"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU003423"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51826"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="OBZ87025.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="430" mass="47787" checksum="0FD86F3CD2E59116" modified="2016-11-30" version="1">MLSCLVKPRLSRSIHTSLQRSAVQPFLLADIGEGITECEIVQWFVKPGSRVAEFDKICEVQSDKASVEISSRYAGNILKLHYQPHEVALVGRPLVDIETEEQSMVDTAVEAIKQHQSEPLKKNMAYQKSWCMPSVRRLLDLYGIEYSHLLGSGKHGMVLKSDVLKHIQQNNLSIKTPQVETPQVEIAPVEQVKAKSVPLTAIQKAMFKTMTKSLSIPQLGYKDEVELNAATEYRKALNKYLADHPDKYPFRKISYLPLLLKSLSLALTHYPILNAQLVNEHQLQYRDAHNIGIAVDSPQGLIVPNIKHVEQKSILQIASEIHRLTELAKKNAIPLADLKGGTISLSNIGSIGGTYANPIVVSQEMAIVAIGSAKRLPFVDTETGKIVPKQMLPISWSADHRVVDGATIAQFSNTWKHFIENPALLASNLH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NDE8</accession>
    <name>A0A1C7NDE8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Splicing factor 3A subunit 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">SF3A1</name>
        <name evidence="10" type="ORF">A0J61_04849</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000247">
        <property type="protein sequence ID" value="OBZ87105.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="FunCoup" id="A0A1C7NDE8">
        <property type="interactions" value="859"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NDE8"/>
    <dbReference type="InParanoid" id="A0A1C7NDE8"/>
    <dbReference type="OrthoDB" id="447637at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071013">
        <property type="term" value="C:catalytic step 2 spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005686">
        <property type="term" value="C:U2 snRNP"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071004">
        <property type="term" value="C:U2-type prespliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045292">
        <property type="term" value="P:mRNA cis splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000381">
        <property type="term" value="P:regulation of alternative mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01800">
        <property type="entry name" value="Ubl_SF3a120"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.790:FF:000002">
        <property type="entry name" value="Splicing factor 3A subunit 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.790:FF:000001">
        <property type="entry name" value="Splicing factor 3a, subunit 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.790">
        <property type="entry name" value="Surp module"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045146">
        <property type="entry name" value="SF3A1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022030">
        <property type="entry name" value="SF3A1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035563">
        <property type="entry name" value="SF3As1_ubi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000061">
        <property type="entry name" value="Surp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035967">
        <property type="entry name" value="SWAP/Surp_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000626">
        <property type="entry name" value="Ubiquitin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15316">
        <property type="entry name" value="SPLICEOSOME ASSOCIATED PROTEIN 114/SWAP SPLICING FACTOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15316:SF1">
        <property type="entry name" value="SPLICING FACTOR 3A SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12230">
        <property type="entry name" value="PRP21_like_P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01805">
        <property type="entry name" value="Surp"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00240">
        <property type="entry name" value="ubiquitin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00648">
        <property type="entry name" value="SWAP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00213">
        <property type="entry name" value="UBQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109905">
        <property type="entry name" value="Surp module (SWAP domain)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50128">
        <property type="entry name" value="SURP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50053">
        <property type="entry name" value="UBIQUITIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="5" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0747">Spliceosome</keyword>
    <feature type="domain" description="SURP motif" evidence="9">
        <location>
            <begin position="33"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="domain" description="SURP motif" evidence="9">
        <location>
            <begin position="136"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="domain" description="Ubiquitin-like" evidence="8">
        <location>
            <begin position="615"/>
            <end position="666"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="284"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="518"/>
            <end position="580"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="299"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="316"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="7">
        <location>
            <begin position="523"/>
            <end position="545"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="553"/>
            <end position="571"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OBZ87105.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="666" mass="74694" checksum="5DB542F045661581" modified="2016-11-30" version="1">MSAMEIDQPQANGNHDSPVVSGIIYPPPDIRKMIDKAAANLATKGPELENHIRETNKDGRFNFLNPNDPYYAYYRFKYQEVKDGXVQNNTQQTQQVQQIQQTFETQQKPMSLAPKEPEPFEFSSPMPAMSAQDLDIMKLTAQFAARNGRAFINQLAQRESRNYQFDFLRPSHSLFPYFTELVKQYTKVFLPPKDLQDKLNANKNDKHHILERVKERVEWVAYQEAERKKKNDEDEKERIAYASIDWHDFVVVETVEFTQADEQADLPPPMSLAELESMSLAQKRLAAMPTESVAKKEEEEPEDVDMDQSDDEDETTPAPITTPKIPDTTAPIKIRTDYKPRLIGTTPIKVAVPTELCPRCGEAIPVDEMAEHMRIELLDPKWKEQKMAMEAKQRDSNLLQEGNDVAKILKNISGLRPDIFGSDEADANKRIREQAEEAKKKDRVIWDGHTATMGLANQRAQKTSIEEQIANMHKKVVGDDIGPQIPGQPHTNYAAYPPAGYSAPQYYAPNHAQLFANQMPGGYMPPPNVVPPPPSSQQPPPPPPSTSGTPTIRKADQEGAGGPEKKPRLDEPEWQATTDPSFSVLIQTPDIPDKPEWNLTGASISINSLLPNTLISTVKDRIASQLGMPAGKQKLTAAGTVLNNSKTLGFYNIAEGTTLSLEVRKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NEP1</accession>
    <name>A0A1C7NEP1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Multifunctional methyltransferase subunit trm112</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_04392</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="2">Interacts with TRM9.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the TRM112 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000214">
        <property type="protein sequence ID" value="OBZ87561.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NEP1"/>
    <dbReference type="FunCoup" id="A0A1C7NEP1">
        <property type="interactions" value="552"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NEP1"/>
    <dbReference type="InParanoid" id="A0A1C7NEP1"/>
    <dbReference type="OrthoDB" id="2187549at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035657">
        <property type="term" value="C:eRF1 methyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043528">
        <property type="term" value="C:tRNA (m2G10) methyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046982">
        <property type="term" value="F:protein heterodimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008276">
        <property type="term" value="F:protein methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016435">
        <property type="term" value="F:rRNA (guanine) methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0160102">
        <property type="term" value="F:tRNA (guanine(10)-N2)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000470">
        <property type="term" value="P:maturation of LSU-rRNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030490">
        <property type="term" value="P:maturation of SSU-rRNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070476">
        <property type="term" value="P:rRNA (guanine-N7)-methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030488">
        <property type="term" value="P:tRNA methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002098">
        <property type="term" value="P:tRNA wobble uridine modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd21089">
        <property type="entry name" value="Trm112-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.20.25.10:FF:000018">
        <property type="entry name" value="Multifunctional methyltransferase subunit TRM112-like B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.25.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039127">
        <property type="entry name" value="Trm112"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005651">
        <property type="entry name" value="Trm112-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12773:SF0">
        <property type="entry name" value="MULTIFUNCTIONAL METHYLTRANSFERASE SUBUNIT TRM112-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12773">
        <property type="entry name" value="UPF0315 PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03966">
        <property type="entry name" value="Trm112p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF158997">
        <property type="entry name" value="Trm112p-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00065633"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ87561.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="123" mass="14154" checksum="026D9AE2BF453410" modified="2016-11-30" version="1">MRLITHNMLQCHVKNCNNNNFPLRFEDVQVEQIEADFNPEFVANMLNKLEWEALCSTAVQLGINTLPAQMPEDAEENEAFLQLVHNVILETHVQQGQMVCPNCNHVYKIRDGIPNMLLAEHEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NFC0</accession>
    <name>A0A1C7NFC0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_04494</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000221">
        <property type="protein sequence ID" value="OBZ87459.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NFC0"/>
    <dbReference type="InParanoid" id="A0A1C7NFC0"/>
    <dbReference type="OrthoDB" id="2287714at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ87459.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="164" mass="18387" checksum="A1A5E34377FFE4DB" modified="2016-11-30" version="1">MFTTHVAAYKLIRKNIGPITSFQHLSGHTRFVSAEDCDKALEQDTIIGSRKFVGVVAPGGTHAKNFVDVALTLLHIPTKRELLHGLRASLQHYDTIHQIEQLTHKGFFVGEISFMIDTRSPATSAASDTAVRIHALSRQLYSSFWDKHTPVSFRGAAHIRFYCR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NFS3</accession>
    <name>A0A1C7NFS3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_04130</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000195">
        <property type="protein sequence ID" value="OBZ87820.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NFS3"/>
    <dbReference type="InParanoid" id="A0A1C7NFS3"/>
    <dbReference type="OrthoDB" id="2294143at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008889669" evidence="2">
        <location>
            <begin position="19"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="28"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="72"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="72"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="85"/>
            <end position="94"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ87820.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="268" mass="30930" checksum="CCA9A8EA5D9E742C" modified="2016-11-30" version="1">MKVPFCIFTIFTIGLVRAATYGRYDENHSSLNEKDYSQNERNHHTKSNTDYDNDHDTNSIYSDSKDTFYDEEYGRSSDAKKEKSTTNTTASSTNQLPPPLLFEWKYAYNPPRVNPFYCTGFYIDHPKYPGLSFAADSIQEIKWRINETELPVWKPNIIWRIRVINSTQHNESVVGANMTLYTGEDMTGSALFPLNVTSPSGFYHYRIMVNYFGQPVHCVYESVPFFVSHDPSEEPVYPGPPIWEGYNSFYYSQDPKYGMAYHNPAVVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NG17</accession>
    <name>A0A1C7NG17_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Serine/arginine-rich splicing factor RS2Z32</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">RS2Z32_1</name>
        <name evidence="6" type="ORF">A0J61_03983</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000185">
        <property type="protein sequence ID" value="OBZ87968.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NG17"/>
    <dbReference type="STRING" id="101091.A0A1C7NG17"/>
    <dbReference type="InParanoid" id="A0A1C7NG17"/>
    <dbReference type="OrthoDB" id="1099063at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.60.10">
        <property type="entry name" value="Zinc finger, CCHC-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050907">
        <property type="entry name" value="SRSF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001878">
        <property type="entry name" value="Znf_CCHC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036875">
        <property type="entry name" value="Znf_CCHC_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23147">
        <property type="entry name" value="SERINE/ARGININE RICH SPLICING FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00098">
        <property type="entry name" value="zf-CCHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00343">
        <property type="entry name" value="ZnF_C2HC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57756">
        <property type="entry name" value="Retrovirus zinc finger-like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50158">
        <property type="entry name" value="ZF_CCHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RRM" evidence="4">
        <location>
            <begin position="56"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="domain" description="CCHC-type" evidence="5">
        <location>
            <begin position="171"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="132"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="176"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="132"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="195"/>
            <end position="242"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OBZ87968.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="276" mass="32602" checksum="6F8BEA0C25FAE576" modified="2016-11-30" version="1">MHISCSKNAFVPILFLTSAYHIIADDIHVKVFEILKYQIVVIVTEEEIELDPTLVVSMLVRNINRYVREQDLKDLFSRYGRVRDFILRDYYAFIEFDSVREADDAAKELNGYRLEDDRLVVQVANVARNRLESRDRDSRRNRDRDYRSDRRHISLPKGSGERALRFQKGSCFECGQTGHRARDCPEKNNGGANSSRRRRSRSQSRSRSPRRSRSPRRRSRSPRRRSRSPRRRSRSPRRRRRSDSRSVSPRRSPSPRRRSSSPRRPLSNERSNNGSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NG77</accession>
    <name>A0A1C7NG77_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Ribosomal protein L37</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">RpL37a_2</name>
        <name evidence="10" type="ORF">A0J61_04214</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Component of the large ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 9">Belongs to the eukaryotic ribosomal protein eL37 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000200">
        <property type="protein sequence ID" value="OBZ87739.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NG77"/>
    <dbReference type="FunCoup" id="A0A1C7NG77">
        <property type="interactions" value="272"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NG77"/>
    <dbReference type="InParanoid" id="A0A1C7NG77"/>
    <dbReference type="OrthoDB" id="10259236at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022625">
        <property type="term" value="C:cytosolic large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="2.20.25.30:FF:000001">
        <property type="entry name" value="Ribosomal protein L37"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.25.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00547">
        <property type="entry name" value="Ribosomal_eL37"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001569">
        <property type="entry name" value="Ribosomal_eL37"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011331">
        <property type="entry name" value="Ribosomal_eL37/eL43"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018267">
        <property type="entry name" value="Ribosomal_eL37_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011332">
        <property type="entry name" value="Ribosomal_zn-bd"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003214">
        <property type="entry name" value="PRK04179.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10768">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L37"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10768:SF0">
        <property type="entry name" value="RIBOSOMAL PROTEIN L37"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01907">
        <property type="entry name" value="Ribosomal_L37e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57829">
        <property type="entry name" value="Zn-binding ribosomal proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01077">
        <property type="entry name" value="RIBOSOMAL_L37E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 9" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="7 9 10" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="6 9" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3 9" id="KW-0699">rRNA-binding</keyword>
    <keyword evidence="5 9" id="KW-0862">Zinc</keyword>
    <keyword evidence="4" id="KW-0863">Zinc-finger</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009805"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU000576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OBZ87739.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="89" mass="10160" checksum="0C0237678AD53C79" modified="2016-11-30" version="1">MTKGTSSFGKRHTKTHTLCRRCGNRSFHKQKKTCAQCGYPAAKIRSFNWSEKGKRRKTTGTGRMAHLKDVQRRFKNGFREGTQAKKVAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NGE0</accession>
    <name>A0A1C7NGE0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">WD repeat-containing protein 81</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">WDR81_0</name>
        <name evidence="4" type="ORF">A0J61_04324</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000209">
        <property type="protein sequence ID" value="OBZ87626.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NGE0"/>
    <dbReference type="STRING" id="101091.A0A1C7NGE0"/>
    <dbReference type="InParanoid" id="A0A1C7NGE0"/>
    <dbReference type="OrthoDB" id="26681at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004672">
        <property type="term" value="F:protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06071">
        <property type="entry name" value="Beach"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1540.10">
        <property type="entry name" value="BEACH domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000409">
        <property type="entry name" value="BEACH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036372">
        <property type="entry name" value="BEACH_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46866">
        <property type="entry name" value="GH12955P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46866:SF1">
        <property type="entry name" value="GH12955P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02138">
        <property type="entry name" value="Beach"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01026">
        <property type="entry name" value="Beach"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81837">
        <property type="entry name" value="BEACH domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50197">
        <property type="entry name" value="BEACH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Protein kinase" evidence="2">
        <location>
            <begin position="122"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="domain" description="BEACH" evidence="3">
        <location>
            <begin position="311"/>
            <end position="573"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="658"/>
            <end position="677"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="664"/>
            <end position="677"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50197"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OBZ87626.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="911" mass="103111" checksum="1282D88082D351FA" modified="2016-11-30" version="1">MGNGYSTQDLKRKIYQDLKIDVAFPFFPLERKTGFSACCVVDIEWLEKLHQASTVLEDIVLKNPSYLRQVTEGSLQKQSPTANVYVTALSKDTAESLSLYTPISNSKSREHQKEERWPLMTYIQSLIEGNGLDQKVELLRDDFDNYTLSDEKQDPIDRVNLIRSMLSPKCKWFKKTLDGQDEEITVQLQNTLSDDEEEPEDLANASLPDIFSIIETDGTFYLLTSYRSTTLQDLLVYNPGVISSSLKRSFVVYQLIRVVASLHDRGILHGNLKPSNILIDENLWIQLAGIEFEPYAPDFDLSQWLYNREASRMIDEIPQEPLVISWVKGNISNFTYLMALNHLAGRREGDPNFYPILPWITDFSGDSVEDGWRNFAQTKFRINKGDEQLDFTFEGPVPHHITDILSDITYYVYQARKTPIPVLCQFVRSKYEPNEYPSSMQRLYQWTPDECIPEFYTDPTIFKSIHPDMPDMQVPAWASSPEDFIKKHSEALESDYVSAHLHYWIDLTFGKDLTGKGAVEAKNVALPLLAGQNSFMKHGIIQLFKDKHPQRGCNWGKVRKESDQAYLKAQSNEQTKTTSIKKTEASYNPEVPGISTAFSSITNRAHRSGSVRTRQTLLSNNASLENATFGLLSHTPSLATTNAHSNTAVSIMINGNVTRDRTPSVHSTASSVDTSRSLPTSSLSAIEPLTSALRAEPIRLSNALSDDYFVDDLDRYEEMITFAAKYKSLMDFPERIKNPVYPDPPHRFAIDINGCTTKLSFSAFSAGTAHDVFCLGQVIQAIYTAGDAKLVDSDDLSPNGYSELNQIDISNDIPYAGKPEIPPSIAGFLDALQSSHWQERPTAKSILCSSFPTMTLPNLQSSFPFPIMIPEIYEYLAAFQQAKWSRRLYLADKWIDRLCDLEDEVSLFYLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NGN7</accession>
    <name>A0A1C7NGN7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Thioredoxin domain-containing protein 5</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">Txndc5</name>
        <name evidence="10" type="ORF">A0J61_03687</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Probable disulfide isomerase, which participates in the folding of proteins containing disulfide bonds. May act as a dithiol oxidase. Acts as a regulator of endoplasmic reticulum-mitochondria contact sites via its ability to regulate redox signals.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000163">
        <property type="protein sequence ID" value="OBZ88272.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NGN7"/>
    <dbReference type="STRING" id="101091.A0A1C7NGN7"/>
    <dbReference type="InParanoid" id="A0A1C7NGN7"/>
    <dbReference type="OrthoDB" id="427280at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="CDD" id="cd02961">
        <property type="entry name" value="PDI_a_family"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="CDD" id="cd02981">
        <property type="entry name" value="PDI_b_family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052250">
        <property type="entry name" value="PDI_TMX3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017937">
        <property type="entry name" value="Thioredoxin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46426">
        <property type="entry name" value="PROTEIN DISULFIDE-ISOMERASE TMX3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46426:SF1">
        <property type="entry name" value="PROTEIN DISULFIDE-ISOMERASE TMX3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00085">
        <property type="entry name" value="Thioredoxin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00421">
        <property type="entry name" value="THIOREDOXIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00194">
        <property type="entry name" value="THIOREDOXIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008889692" evidence="8">
        <location>
            <begin position="22"/>
            <end position="605"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="551"/>
            <end position="574"/>
        </location>
    </feature>
    <feature type="domain" description="Thioredoxin" evidence="9">
        <location>
            <begin position="5"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="domain" description="Thioredoxin" evidence="9">
        <location>
            <begin position="196"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="136"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="139"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="176"/>
            <end position="191"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00045246"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OBZ88272.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="605" mass="67635" checksum="357E05622EC9F8BA" modified="2016-11-30" version="1">MHLSLAAGTALLICLLKTVSAETTELRPDNIKKHISTGTWLIEHFSPYCPHCQNFAPHWKKATDEFNDLAKEYDLYFGTIDCSTQGDLCDEHEVMAYPTLQLWEDGKKVERYTAKTAYEPLVEYIQAKIDMKKSLKAEEEAEEEAEEEEVEEEVEGELVVEGEEDENLIELKDNQEAEDEAEELSEQEQEEEEVVAALALPNPEGISVNMDGTQLKEIASGSTPWFIKFYAPWCGHCKALAPTWTQMATQLQGQVNVGEVDCQALPAVCQEYGVQGFPTLKMLGNGEPVQYLSDRSLASLTQFALSHSGPTVKKVDFNELIQHLAVKDVAIVYLLNEAKGNVPVLIESIANEHAATLPFYASSDEASFKRFGVSPSDLPVLLIAKDNSFQVYGSHDFSNTKMAKEALARWIEQEQYPLVTQLGAHNGQAILKGTQPVVLHLYRTKANSKKFYQMATAKAKSSSDVIFAEMDYSLWKEYAATKFDVELKEASDQVLIYDAPHYKVYKAGLDHQLFSLDHTEAVYEALDHLDQLEGQTVLSPHEKLGVSVTNAFAWMGVHWIFSLVSLSALGAFVYRYLTHHSPKRVSAGILPSFKAVPTTSDYHKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NGQ8</accession>
    <name>A0A1C7NGQ8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DNA damage-binding protein CMR1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">A0J61_03743</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">DNA-binding protein that binds to both single- and double-stranded DNA. Binds preferentially to UV-damaged DNA. May be involved in DNA-metabolic processes.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the WD repeat DDB2/WDR76 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000168">
        <property type="protein sequence ID" value="OBZ88198.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NGQ8"/>
    <dbReference type="InParanoid" id="A0A1C7NGQ8"/>
    <dbReference type="OrthoDB" id="10258692at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006974">
        <property type="term" value="P:DNA damage response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:2000001">
        <property type="term" value="P:regulation of DNA damage checkpoint"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00167">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001005">
        <property type="entry name" value="SANT/Myb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050853">
        <property type="entry name" value="WD_repeat_DNA-damage-binding"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14773">
        <property type="entry name" value="WD REPEAT-CONTAINING PROTEIN 76"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14773:SF0">
        <property type="entry name" value="WD REPEAT-CONTAINING PROTEIN 76"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00249">
        <property type="entry name" value="Myb_DNA-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50090">
        <property type="entry name" value="MYB_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0227">DNA damage</keyword>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="Myb-like" evidence="4">
        <location>
            <begin position="209"/>
            <end position="253"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU365004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OBZ88198.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="282" mass="32192" checksum="DFDE348BE7A4804C" modified="2016-11-30" version="1">MTKELTPYEKARLENIELNKELLASLEIGSAKRSLNATEVITVKKRKRAPVTSVKKEQPVIQIRKSSRIRGEKALEITLDDHEAVKALDEAVKQDPRYAEMVDAGKLLTADEYFPEDIKAKAIRVDGHFTGWVNPEIMEKYGLASSATEAWEENGGGTYTFADPTGSGKKRKKGPSNAKAEALKMFKKNPNQYFYRHNEPGEEQWMHDWSEEEKQLFLKVAKMYGCGDKWGLFASYIPHRFGYQCSSFYRHDIIQNGLVFDPNFQFTPSGEPVYIGNQRSRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NHE3</accession>
    <name>A0A1C7NHE3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_03783</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000170">
        <property type="protein sequence ID" value="OBZ88169.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NHE3"/>
    <dbReference type="InParanoid" id="A0A1C7NHE3"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ88169.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="149" mass="16753" checksum="A6592C2BEAE7B8C7" modified="2016-11-30" version="1">MNQDNVLPTNSVESDDKTSDVDIESCDVEEIELKNKISGEMSNKAIVIDSTDCELDIETSVEETEATKCAVELVVNKIIEDSEEAIQKVISDVARKKEMEQIFFVGSEFSDIDELRARAQELGKKYSCPITTDKSYKKLQTITFDLSAW</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NHJ3</accession>
    <name>A0A1C7NHJ3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">LYR motif-containing protein 5A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">lyrm5a</name>
        <name evidence="3" type="ORF">A0J61_03342</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the complex I LYR family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000142">
        <property type="protein sequence ID" value="OBZ88593.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NHJ3"/>
    <dbReference type="STRING" id="101091.A0A1C7NHJ3"/>
    <dbReference type="InParanoid" id="A0A1C7NHJ3"/>
    <dbReference type="OrthoDB" id="10258445at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090324">
        <property type="term" value="P:negative regulation of oxidative phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022904">
        <property type="term" value="P:respiratory electron transport chain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd20265">
        <property type="entry name" value="Complex1_LYR_ETFRF1_LYRM5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008011">
        <property type="entry name" value="Complex1_LYR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045296">
        <property type="entry name" value="Complex1_LYR_ETFRF1_LYRM5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052000">
        <property type="entry name" value="ETFRF1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21024:SF0">
        <property type="entry name" value="ELECTRON TRANSFER FLAVOPROTEIN REGULATORY FACTOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21024">
        <property type="entry name" value="GROWTH HORMONE-INDUCIBLE SOLUBLE PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05347">
        <property type="entry name" value="Complex1_LYR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Complex 1 LYR protein" evidence="2">
        <location>
            <begin position="5"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009508"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF05347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ88593.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="82" mass="10111" checksum="A322121B9D1472DB" modified="2016-11-30" version="1">MLRSRVISLYKQLVYLGREYPAGYTDFFRPKLKDAFMKKKDLTDPQEIEKAIQFGEYIIKELETLYYLRKYRTLRKRYNETQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NHU0</accession>
    <name>A0A1C7NHU0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Angiogenic factor with G patch and FHA domains 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">Aggf1</name>
        <name evidence="4" type="ORF">A0J61_03396</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000145">
        <property type="protein sequence ID" value="OBZ88550.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NHU0"/>
    <dbReference type="STRING" id="101091.A0A1C7NHU0"/>
    <dbReference type="InParanoid" id="A0A1C7NHU0"/>
    <dbReference type="OrthoDB" id="21470at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.200.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053027">
        <property type="entry name" value="AGGF1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000253">
        <property type="entry name" value="FHA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000467">
        <property type="entry name" value="G_patch_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008984">
        <property type="entry name" value="SMAD_FHA_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23106">
        <property type="entry name" value="ANGIOGENIC FACTOR WITH G PATCH AND FHA DOMAINS 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23106:SF24">
        <property type="entry name" value="ANGIOGENIC FACTOR WITH G PATCH AND FHA DOMAINS 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00498">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01585">
        <property type="entry name" value="G-patch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00240">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00443">
        <property type="entry name" value="G_patch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49879">
        <property type="entry name" value="SMAD/FHA domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50006">
        <property type="entry name" value="FHA_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50174">
        <property type="entry name" value="G_PATCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FHA" evidence="2">
        <location>
            <begin position="137"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="domain" description="G-patch" evidence="3">
        <location>
            <begin position="326"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="237"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="355"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="246"/>
            <end position="256"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50174"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OBZ88550.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="397" mass="45343" checksum="F73BBDC2DDDE26F2" modified="2016-11-30" version="1">MIAKATDDELTNQLDDYLKTTSDSKQDESDWTFDEEKGVYVIHSRRLVMYQLENQWICGDYDSFYTDRYLFDSTLQAWYDTLTEEYSVFDESTQTYVPIDHGGDAGQPLSNQSIRFVVKSSPFYQLGQVVLADANGLSVGRDRSWDCRLRLPEMIVSKYHAMIFWDPKLKQFCLIDNGSQHGTFLNDKRLSEAKQSSLPMPLDHLDRIRIGSTELEVHYHSQTGWPCQECISNSLVDTNSGKKKPTSSTYATSATPEELEESRRTWIKNTKKEYMDHNSSGSSYINRAQIRRMTTQPEKFIKENDTPSPSLPDPSSVVVSASPTVVKGIGAHMLQKLGWQEGQGLGRHQDGVLEPIAPTANNTRSGLGHTQPMHNNNDNMSRKDRQRIIQQQRYYQT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NI75</accession>
    <name>A0A1C7NI75_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="1">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">ssp1</name>
        <name evidence="12" type="ORF">A0J61_03237</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="1"/>
    <dbReference type="EMBL" id="LUGH01000136">
        <property type="protein sequence ID" value="OBZ88718.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NI75"/>
    <dbReference type="FunCoup" id="A0A1C7NI75">
        <property type="interactions" value="539"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NI75"/>
    <dbReference type="InParanoid" id="A0A1C7NI75"/>
    <dbReference type="OrthoDB" id="68483at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035556">
        <property type="term" value="P:intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd14008">
        <property type="entry name" value="STKc_LKB1_CaMKK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000206">
        <property type="entry name" value="Serine/threonine-protein kinase Ssp1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24346">
        <property type="entry name" value="MAP/MICROTUBULE AFFINITY-REGULATING KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24346:SF77">
        <property type="entry name" value="SERINE THREONINE PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 12" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="11">
        <location>
            <begin position="51"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="413"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="527"/>
            <end position="565"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="423"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="10">
        <location>
            <begin position="436"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="447"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="80"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="OBZ88718.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="582" mass="65765" checksum="061B8086304C075B" modified="2016-11-30" version="1">MLKRRASENPTTLKPPQEIVLGSHYYHDVLTTTTLVKTYDTETGNKLINNFMILQEIGRGVHGKVKLAQDTFTGELVAIKIVDKKNRRRQMGYSLLRGSQAQGSEPASKENEDKIRREIAILSKCYHPNVVRLYEVIDDPTSRKIYMALEYTANGEIEWRDENEKPVMTVQDARRIFRDIVCGLDYLHYQGIIHRDIKPANLLLSHDGIAKISDFGVSYYNDLLAVNNASLLEAAEEKVIQKIDRELAETAGTPAFFAPELCCAGETTSISTSSSISSTKKLRISKAVDVWALGVTLYCFIFGQCPFVAATEFELFDTIPTQPLTFPSGFDLDPELQDLLEKLLVKNPHDRITLDQVKVHPWVIRDLSNRQEWLIRSDPRHYLIEKPQELETTESVGLMERLRQSIRKLSFSFGSNNRRRSSKQFSSPRHLSYQSPHHHTMHRHSQPIMSKQPSYSKSLLPHTTNSVTPTVSLSTGHTLILNSGLHSSIIPSPSSPTTIQPAPLQSISYLSEDDSSSSIIDEEDEEYHLHLEPEGRQSTSSRRPDISRRVSSSSSSSGIAFGTRYRNQMTQLTPLEVMANKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NIC5</accession>
    <name>A0A1C7NIC5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Histone-lysine N-methyltransferase SET5</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">SET domain-containing protein 5</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="primary">SET5</name>
        <name evidence="14" type="ORF">A0J61_03166</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>L-lysyl-[histone] + S-adenosyl-L-methionine = N(6)-methyl-L-lysyl-[histone] + S-adenosyl-L-homocysteine + H(+)</text>
            <dbReference type="Rhea" id="RHEA:10024"/>
            <dbReference type="Rhea" id="RHEA-COMP:9845"/>
            <dbReference type="Rhea" id="RHEA-COMP:9846"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29969"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:61929"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="9">
            <dbReference type="Rhea" id="RHEA:10025"/>
        </physiologicalReaction>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000132">
        <property type="protein sequence ID" value="OBZ88785.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NIC5"/>
    <dbReference type="FunCoup" id="A0A1C7NIC5">
        <property type="interactions" value="224"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NIC5"/>
    <dbReference type="InParanoid" id="A0A1C7NIC5"/>
    <dbReference type="OrthoDB" id="438641at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042799">
        <property type="term" value="F:histone H4K20 methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045814">
        <property type="term" value="P:negative regulation of gene expression, epigenetic"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd20071">
        <property type="entry name" value="SET_SMYD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.220.160">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.2220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.270.10">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001214">
        <property type="entry name" value="SET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046341">
        <property type="entry name" value="SET_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002893">
        <property type="entry name" value="Znf_MYND"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46402:SF2">
        <property type="entry name" value="HISTONE-LYSINE N-TRIMETHYLTRANSFERASE SMYD5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46402">
        <property type="entry name" value="SET AND MYND DOMAIN-CONTAINING PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00856">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01753">
        <property type="entry name" value="zf-MYND"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00317">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144232">
        <property type="entry name" value="HIT/MYND zinc finger-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82199">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50280">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50865">
        <property type="entry name" value="ZF_MYND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <keyword evidence="5 10" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="SET" evidence="12">
        <location>
            <begin position="86"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="domain" description="MYND-type" evidence="13">
        <location>
            <begin position="146"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="54"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="54"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00042380"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00044528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00048619"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="OBZ88785.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="412" mass="47604" checksum="4841AF560469CFC5" modified="2016-11-30" version="1">MSEKIIPTEEELVSAIKSIKLEHPEAGIKTVTSQVLTQQPEWQVSEKRVKKYMQSTGLTNSSGTPKEPVKSGLPDDPSVPVSYIDPKLDFKSVSDCVVARMVDPVTGKGLFAARDIKKDEVIFTETPFSYFPPWEAFQLTRNGNACGLCCKPILYPNRLTQHCGHCNVYYCSKECRIKAWESFHQLECTHLNNKIGSFITFCELEKWQAPMAVSRIYAQLILAHQRGELDQVMGHLDAFATVSQEERQAKETEWIFMEAPTRELWTRARDLLRAAYKIPPKRCKITKPLPNDLLESLFEKEETFLNFLGKFNINNQNGGMYLVHSHINHNCYPNVSIDYPQKNSQYKITVRAIREIKKDEQLFETYVNPRWNKETRQTYLDKSYLFTCKCDRCEQDIPLTDELRQGLRLRGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NIG5</accession>
    <name>A0A1C7NIG5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_03056</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000125">
        <property type="protein sequence ID" value="OBZ88902.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NIG5"/>
    <dbReference type="InParanoid" id="A0A1C7NIG5"/>
    <dbReference type="OrthoDB" id="2272201at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ88902.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="216" mass="24854" checksum="1194F3924C5B25A3" modified="2016-11-30" version="1">MNGSKKFKLFTHKKHKVTPVKESLSLEDLTTLVRRLSVQIDDIESQVRKPIRWIMDPYATSVPEDYASLIKRLETSDPTHLYFTVESAGGIPWPEPHTLSNPTPLEAQYVHWCTLLRCLPWMDHMTAQYVKTMALYAMRDILASNPPNITSTPPDIPNFPNIPSHSSSVISPPKKIPSPVFSHDQFSKWSQYKHKKRLTDKTPSLQNLRKIGSWFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NIZ6</accession>
    <name>A0A1C7NIZ6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">WHI2-like protein P4H10.16c</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_02933</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000118">
        <property type="protein sequence ID" value="OBZ89025.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NIZ6"/>
    <dbReference type="FunCoup" id="A0A1C7NIZ6">
        <property type="interactions" value="166"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NIZ6"/>
    <dbReference type="InParanoid" id="A0A1C7NIZ6"/>
    <dbReference type="OrthoDB" id="9451547at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54695">
        <property type="entry name" value="POZ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ89025.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="307" mass="35569" checksum="E28123316AC2BEC1" modified="2016-11-30" version="1">MSSESPIMQVPEPEESYNNEELIYQQHQDDLDEFDNHDTIPQKLKLDLRGTRMELHRDTLINLPESLLIAMFPNGLVLARPHEDFDEDDEDDDDDGHSVGMDEQVNIVDFDPACLEYVLQFYTHAAQVRDQNQQNPELQHLLAASAASSPVYYTLLTKQPIIVLREELEYFCLPTQKNQNAKHLKLAAGKYLTKHDLIFDALQKNISRENNVAEQHLIDMLCDAGFQRDDHWGYREIEPLKTTIVSMALVLLKTIGPDNHMATAQKLFLFWRKPARKCWWDGDSVEIEGQSIRLWARRTWTLELALV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NL16</accession>
    <name>A0A1C7NL16_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Chitin deacetylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">CDA_9</name>
        <name evidence="4" type="ORF">A0J61_02770</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000109">
        <property type="protein sequence ID" value="OBZ89176.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NL16"/>
    <dbReference type="InParanoid" id="A0A1C7NL16"/>
    <dbReference type="OrthoDB" id="407355at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004099">
        <property type="term" value="F:chitin deacetylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009272">
        <property type="term" value="P:fungal-type cell wall biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.370">
        <property type="entry name" value="Glycoside hydrolase/deacetylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011330">
        <property type="entry name" value="Glyco_hydro/deAcase_b/a-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002509">
        <property type="entry name" value="NODB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050248">
        <property type="entry name" value="Polysacc_deacetylase_ArnD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10587:SF98">
        <property type="entry name" value="CHITIN DEACETYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10587">
        <property type="entry name" value="GLYCOSYL TRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01522">
        <property type="entry name" value="Polysacc_deac_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88713">
        <property type="entry name" value="Glycoside hydrolase/deacetylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51677">
        <property type="entry name" value="NODB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008889765" evidence="2">
        <location>
            <begin position="19"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="domain" description="NodB homology" evidence="3">
        <location>
            <begin position="144"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="372"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="374"/>
            <end position="392"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OBZ89176.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="484" mass="53045" checksum="7A87BFEBFB3D8151" modified="2016-11-30" version="1">MRVTQSVFFVIAASQAYAATIQKRGYAPQFQPSFPNVNEPSGVVTSYNPGPYDTSDTLSTAQLTGFPTPWTSPPTDSEEVLAVYNKIDWSFVPKAPIRKRDAYGNWLSNSDGASDPYCWWSSTNCLKPKASYLPPDIYTCPSSGDWGLNYDDGPFNRYTGSNARKENEYAEPTLYNFLAKHNVHSTLFYIGSNVATYPAAAKRGLNNGHQLCVHTWSHPPMTTQTDKQVVAELYWTLKAIKAATGVTSKCWRPPQGDVDDRVRAIAWQMGLRTILWDEDTDDWNVSGGPNGGTLSPRKVDAKFAKWINNYKTGKDISGHIVLEHELNHVTVNLSMFWMPKLKETFNVIPALSCNGITRPYWEESFVYPVAEANSPSTKSTTTTTSKPATTSGSTKTIVTISTQTAAQTTTKKITTTKKVTTTTAKKVTTTITKAITTSTKITSPTSTSCIAGVAGKKQGNGNTGYCCATSDDCLETCRSGKCDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NLB2</accession>
    <name>A0A1C7NLB2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Protein STB2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">STB2</name>
        <name evidence="4" type="ORF">A0J61_02329</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000086">
        <property type="protein sequence ID" value="OBZ89629.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NLB2"/>
    <dbReference type="STRING" id="101091.A0A1C7NLB2"/>
    <dbReference type="InParanoid" id="A0A1C7NLB2"/>
    <dbReference type="OrthoDB" id="19806at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070822">
        <property type="term" value="C:Sin3-type complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038919">
        <property type="entry name" value="STB2/STB2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059025">
        <property type="entry name" value="STB6_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31011">
        <property type="entry name" value="PROTEIN STB2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31011:SF2">
        <property type="entry name" value="PROTEIN STB2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25995">
        <property type="entry name" value="STB6_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="STB6-like N-terminal" evidence="3">
        <location>
            <begin position="3"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="383"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="434"/>
            <end position="550"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="633"/>
            <end position="664"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="395"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="438"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="467"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="483"/>
            <end position="500"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="509"/>
            <end position="529"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF25995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OBZ89629.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="770" mass="87572" checksum="186BA9DEEE503FB7" modified="2016-11-30" version="1">MAATCGLSVIEEQQELRGYQIYIVEQWVCNRKIDSNVVKVFTGDENHVIQVAVIAISTAELQQPRPQIQAFLNVGSHLKYKPTPLGEISLTNPGELPFDMDMVLVPDGDYDKWIKRTYVNINLRRANCTGRSSLNLRPPNPASEEKFRSLYRIADTAKFEDAVINLVSLVQIALYLFDLLHRDYIDGLICDETTAAFWEFYTKYDPVKTTEFSLKEPWMEPHLLAAIISKLLMCRNKLQDYNFTTIKDPFLDYDSFRADIGDYQRHKNIQITRLINLETLAKLNEHTSSQLKVKKVIKSKLDDISGITNSPLFSETSDPETFRHHATIESLRTIWRPRLKGSSHHSTDQQSNELLHMIKGVSRTGGAAVDMLSRVAGSIPWISTADTGKKDTNRSPTLGGSSPSSSHMNADSLMVASPQRTSYQGDQEDELGFRTVTPSRKPSPLSLQKSPSFSSTPNTPHLMHQDSTSPLSAISSTNSSSTKQLNHQDIPSYVQSTNMMPISPGLRISRSSETTSSHPDSTTPSTTSTKHTRQTEGDFVPYKPNRSAIRHTRSVSDSILLSSLFTKTLTNEPEDRVTALQSPFDQYESSLKTRRRSQTALDIIPKIDTKPVTKINVQTYLAYEQLCQQQRMLQQAYQEIKSLADTYEKTANELKNLYEARSQQFEIVQKDSRHVMDDQNETERRLKDVEDNSAKIHYELKVMNDKLKDIEDNVGTFYGKVDLLEQKMDDSQQSITTMLIIGNYFNHYWLKVVEWVQWLGFIQQNKVKDN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NLE6</accession>
    <name>A0A1C7NLE6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="8">3-hydroxybenzoate 4-monooxygenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">mobA</name>
        <name evidence="8" type="ORF">A0J61_02041</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the PheA/TfdB FAD monooxygenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000072">
        <property type="protein sequence ID" value="OBZ89917.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NLE6"/>
    <dbReference type="STRING" id="101091.A0A1C7NLE6"/>
    <dbReference type="InParanoid" id="A0A1C7NLE6"/>
    <dbReference type="OrthoDB" id="1716816at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016709">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.9.10">
        <property type="entry name" value="D-Amino Acid Oxidase, subunit A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012941">
        <property type="entry name" value="Phe_hydrox_C_dim_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038220">
        <property type="entry name" value="PHOX_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050641">
        <property type="entry name" value="RIFMO-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43004:SF19">
        <property type="entry name" value="BINDING MONOOXYGENASE, PUTATIVE (JCVI)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43004">
        <property type="entry name" value="TRK SYSTEM POTASSIUM UPTAKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07976">
        <property type="entry name" value="Phe_hydrox_dim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00420">
        <property type="entry name" value="RNGMNOXGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="8" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding" evidence="6">
        <location>
            <begin position="15"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="domain" description="Phenol hydroxylase-like C-terminal dimerisation" evidence="7">
        <location>
            <begin position="412"/>
            <end position="573"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF07976"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OBZ89917.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="575" mass="64666" checksum="5133EF1EA722B741" modified="2016-11-30" version="1">MITADSTPLPPPPNEVDFLVVGGGPVGLLAANLAVQAGFTVRILDIETEPNHWGRGDWIHGRTLELLERANLASELLKTGVKVEKMTSYKNGTIQKEIPFVPEDAESKYQYLLCVGQHITESSLQSQLSEHDVQVERPSTVVQMTREADSTYPVIATVMHLGKGSEQVRCKYLLGCDGAHSDIRQQLNIAYEGTTTETHAGVLDALIRTNFASRKEVCLVQSDHAKTISMFPRENGLTRIFVHFNENEHELRKEQHNRNKIQVEDIQREAKRALLPHRIEFLGILYWTVYVVGQRSASQLASEDHRVFLCGDAAHSQSPTLGQGVNTGFGDIFNLIWKICLVEKGQMNRSLLSSYHYERWPIAQKVLEVDKIASKAAAGHEATDYCQVVEKHRSFTSGFGIHYTAHPHLVTTSEEDTNYHLQPGMRAPNFKVFSVQTGKKIRLFDIQQAVPSWLTFTLLVLVHDIRVTHGAVKTLREHLQPHQETFPATQVMLVTTSTMDQIQSVAMDTSCLVMDKLNQAQCHRAYHQTSKHSSNHLIQVVVVRPDGYIGTICRHENDGVYLSEQVAHYFNQLSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NLW7</accession>
    <name>A0A1C7NLW7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Molybdopterin synthase catalytic subunit</fullName>
            <ecNumber evidence="4">2.8.1.12</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">Molybdenum cofactor synthesis protein 2 large subunit</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="4">Molybdenum cofactor synthesis protein 2B</fullName>
            <shortName evidence="4">MOCS2B</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">MOCS2</name>
        <name evidence="5" type="ORF">A0J61_01833</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Catalytic subunit of the molybdopterin synthase complex, a complex that catalyzes the conversion of precursor Z into molybdopterin. Acts by mediating the incorporation of 2 sulfur atoms from thiocarboxylated MOCS2A into precursor Z to generate a dithiolene group.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>2 [molybdopterin-synthase sulfur-carrier protein]-C-terminal-Gly-aminoethanethioate + cyclic pyranopterin phosphate + H2O = molybdopterin + 2 [molybdopterin-synthase sulfur-carrier protein]-C-terminal Gly-Gly + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:26333"/>
            <dbReference type="Rhea" id="RHEA-COMP:12202"/>
            <dbReference type="Rhea" id="RHEA-COMP:19907"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:58698"/>
            <dbReference type="ChEBI" id="CHEBI:59648"/>
            <dbReference type="ChEBI" id="CHEBI:90778"/>
            <dbReference type="ChEBI" id="CHEBI:232372"/>
            <dbReference type="EC" id="2.8.1.12"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="4">Cofactor biosynthesis; molybdopterin biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Heterotetramer; composed of 2 small (MOCS2A) and 2 large (MOCS2B) subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the MoaE family. MOCS2B subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.8.1.12" evidence="4"/>
    <dbReference type="EMBL" id="LUGH01000063">
        <property type="protein sequence ID" value="OBZ90112.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NLW7"/>
    <dbReference type="STRING" id="101091.A0A1C7NLW7"/>
    <dbReference type="InParanoid" id="A0A1C7NLW7"/>
    <dbReference type="OrthoDB" id="5531344at2759"/>
    <dbReference type="UniPathway" id="UPA00344"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990140">
        <property type="term" value="C:molybdopterin synthase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030366">
        <property type="term" value="F:molybdopterin synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006777">
        <property type="term" value="P:Mo-molybdopterin cofactor biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00756">
        <property type="entry name" value="MoaE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.1170.40:FF:000002">
        <property type="entry name" value="Molybdopterin synthase catalytic subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1170.40">
        <property type="entry name" value="Molybdopterin biosynthesis MoaE subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03052">
        <property type="entry name" value="MOC2B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036563">
        <property type="entry name" value="MoaE_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028888">
        <property type="entry name" value="MOCS2B_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003448">
        <property type="entry name" value="Mopterin_biosynth_MoaE"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23404">
        <property type="entry name" value="MOLYBDOPTERIN SYNTHASE RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02391">
        <property type="entry name" value="MoaE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54690">
        <property type="entry name" value="Molybdopterin synthase subunit MoaE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 4" id="KW-0501">Molybdenum cofactor biosynthesis</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0808">Transferase</keyword>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="103"/>
            <end position="104"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="119"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="126"/>
            <end position="128"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OBZ90112.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="148" mass="16545" checksum="2A660612501CA46F" modified="2016-11-30" version="1">MIKNIIEISSQELPSLELVADLVQDDSAGAISTFSGTTRDEFEGKKVIELEYEAYIPMAKKVLQELVLETRDKWDLKHIAVYHRTGVVPVGKVSVIIATSSKHRADSLNAVGYLIDELKARCPIWKREVYEDGSVWKGSCTGCKKAEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NLX6</accession>
    <name>A0A1C7NLX6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">DNA/RNA-binding protein KIN17</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">Kin</name>
        <name evidence="7" type="ORF">A0J61_01975</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the KIN17 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000069">
        <property type="protein sequence ID" value="OBZ89990.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NLX6"/>
    <dbReference type="FunCoup" id="A0A1C7NLX6">
        <property type="interactions" value="843"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NLX6"/>
    <dbReference type="InParanoid" id="A0A1C7NLX6"/>
    <dbReference type="OrthoDB" id="10266249at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003690">
        <property type="term" value="F:double-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006974">
        <property type="term" value="P:DNA damage response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.2030:FF:000001">
        <property type="entry name" value="DNA/RNA-binding protein KIN17, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.2030">
        <property type="entry name" value="DNA/RNA-binding protein Kin17, conserved domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056767">
        <property type="entry name" value="C2H2-Znf_KIN17"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019447">
        <property type="entry name" value="DNA/RNA-bd_Kin17_WH-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037321">
        <property type="entry name" value="KIN17-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038254">
        <property type="entry name" value="KIN17_WH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12805:SF0">
        <property type="entry name" value="DNA_RNA-BINDING PROTEIN KIN17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12805">
        <property type="entry name" value="KIN17 KIN, ANTIGENIC DETERMINANT OF RECA PROTEIN HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25095">
        <property type="entry name" value="C2H2-zf_KIN17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10357">
        <property type="entry name" value="WH_KIN17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01253">
        <property type="entry name" value="Kin17_mid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="6">
        <location>
            <begin position="28"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="177"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="236"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="236"/>
            <end position="253"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS00028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OBZ89990.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="289" mass="32487" checksum="9BAB01A12F355508" modified="2016-11-30" version="1">MPKAEFMSPKAIANRMKSKGLQKLKFYCQACEKQCRDENGFKCHIMSESHQRQMLLVAANPGKFVHNYSEEFKRDFLSLLSRAHGTKRVFANKVYQEYIAHKEHIHMNATKWNSLTEFCKQMGRQGILRVDETERGLHIAWVDNSPKALARQAAIQKMDRAKKDDEERDIQLLKEQMEKASKSAEDRGVAEQEVTELKREGEEPIKLSLSMKPAAPIVEAPKSTGSKMMLGGMKKKTSLSALAKKSSTPSTTPANGNSMKVGGMMTMKRKTGSDSQDDSDSKRLKSVSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NLZ6</accession>
    <name>A0A1C7NLZ6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_01846</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000063">
        <property type="protein sequence ID" value="OBZ90117.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NLZ6"/>
    <dbReference type="InParanoid" id="A0A1C7NLZ6"/>
    <dbReference type="OrthoDB" id="2421456at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ90117.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="491" mass="56114" checksum="7E12711BFBACC6F5" modified="2016-11-30" version="1">MSRTQVVTAIIELNAFVDATENPSLNDFISLNFKSFKDHNVSDLSHFRESIVNAFKQVMAKLKPETEIDPQIDSLLLDEAFYKNKKTPAAIRHILFQWYHLLSEGHDLDAFFDKHRAEVNSFLHTKTTEPRALMDKMSIKMLQNYGNLSNKERNILKSCLSYIVDLVDGVDIYKQHIGNKFFWEALDEDSQEEISNEVHEDISAFCSPIIEAMKKDIDTAHVLILEKKIELIKQKKKHTTEFQTLMAFNYLIDNEHEWLLNKKFSETELVCHLNDLLKIFFANTNIVTKIGETTASSSKESRSINEQNFSKGSSSSFITSGTFFSSTNTSSSERSMSGRKIDLLVTTKQKVELSCCEFKASSSSSLTCHQRSKNLRLNQGVMESLRRMHIDSKVIGLNWEGKYGYLFALKQVNGLYLGKKIGYVNLPARADVVNHNFVNTLKLIVAWKGFLVDLEKKIAENMMLPPADSSEHLLTCHTPQYIPNKRQRGSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NMW7</accession>
    <name>A0A1C7NMW7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">CTD nuclear envelope phosphatase 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">cnep-1_0</name>
        <name evidence="2" type="ORF">A0J61_02129</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000076">
        <property type="protein sequence ID" value="OBZ89826.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NMW7"/>
    <dbReference type="STRING" id="101091.A0A1C7NMW7"/>
    <dbReference type="InParanoid" id="A0A1C7NMW7"/>
    <dbReference type="OrthoDB" id="277011at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016791">
        <property type="term" value="F:phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07521">
        <property type="entry name" value="HAD_FCP1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1000:FF:000093">
        <property type="entry name" value="NLI interacting factor-like phosphatase family protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011948">
        <property type="entry name" value="Dullard_phosphatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004274">
        <property type="entry name" value="FCP1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050365">
        <property type="entry name" value="TIM50"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02251">
        <property type="entry name" value="HIF-SF_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12210">
        <property type="entry name" value="DULLARD PROTEIN PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03031">
        <property type="entry name" value="NIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00577">
        <property type="entry name" value="CPDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50969">
        <property type="entry name" value="FCP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FCP1 homology" evidence="1">
        <location>
            <begin position="57"/>
            <end position="224"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50969"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ89826.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="245" mass="27848" checksum="5B9D389113458F22" modified="2016-11-30" version="1">MPTTTVTGSNSNSSQPLILQKIYQLFTFILKYIQSIFLLNHNPKTAKRNTSLQKGLQYYKGKTLVLDLDETLVHSVRLGTSESIHVSASIKKKTIEVINDQQSILYEVYKRPHVDFFLSTISKWYKLVIFTASMSEYADPVIDWLDGDQTLISQRYFRQSCTLKGGNYLKDISVAEPDLSKVCLIDNSPAAYELCQENAIPLPTWISNPKDDCLLDLLPLLDALRFTADVRSILSLRDPETKSIY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NNY1</accession>
    <name>A0A1C7NNY1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Pathogenesis-related protein 5</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_01159</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000033">
        <property type="protein sequence ID" value="OBZ90797.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NNY1"/>
    <dbReference type="STRING" id="101091.A0A1C7NNY1"/>
    <dbReference type="InParanoid" id="A0A1C7NNY1"/>
    <dbReference type="OrthoDB" id="430315at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.110.10:FF:000004">
        <property type="entry name" value="THAUMATIN-LIKE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.110.10">
        <property type="entry name" value="Thaumatin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037176">
        <property type="entry name" value="Osmotin/thaumatin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001938">
        <property type="entry name" value="Thaumatin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31013">
        <property type="entry name" value="THAUMATIN FAMILY PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31013:SF2">
        <property type="entry name" value="THAUMATIN-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00314">
        <property type="entry name" value="Thaumatin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002703">
        <property type="entry name" value="Thaumatin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00347">
        <property type="entry name" value="THAUMATIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00205">
        <property type="entry name" value="THN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49870">
        <property type="entry name" value="Osmotin, thaumatin-like protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51367">
        <property type="entry name" value="THAUMATIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="disulfide bond" evidence="1">
        <location>
            <begin position="23"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="1">
        <location>
            <begin position="133"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="1">
        <location>
            <begin position="143"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="1">
        <location>
            <begin position="163"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="1">
        <location>
            <begin position="173"/>
            <end position="183"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR002703-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ90797.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="223" mass="23386" checksum="03F742EF9E693EA1" modified="2016-11-30" version="1">MYATAYLIYIVFSSKSIVVQNNCKQIVSVGVLTNGVGGGPEQSFDLTPGASNSFSKPDQWGGRVWGRYSCSGSSGKNLEYCNTPGASNPASLAEFFFKGSGGKDFYDISLVDGYNIPMSITPSGGGDANGYSCGSPQCQMNECPAEYAVKDATGNIISCQSACSKTGTDEHCCTGSYNDPNTCTPSGSSAVIKEACPDAYSFAYDDQTSTFQCEATSYTVSLC</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NP85</accession>
    <name>A0A1C7NP85_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Rhomboid-type serine protease</fullName>
            <ecNumber evidence="10">3.4.21.105</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">A0J61_01169</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Serine protease involved in intramembrane proteolysis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 10">
            <text>Cleaves type-1 transmembrane domains using a catalytic dyad composed of serine and histidine that are contributed by different transmembrane domains.</text>
            <dbReference type="EC" id="3.4.21.105"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 10">Membrane</location>
            <topology evidence="2 10">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the peptidase S54 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.21.105" evidence="10"/>
    <dbReference type="EMBL" id="LUGH01000034">
        <property type="protein sequence ID" value="OBZ90790.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NP85"/>
    <dbReference type="STRING" id="101091.A0A1C7NP85"/>
    <dbReference type="InParanoid" id="A0A1C7NP85"/>
    <dbReference type="OrthoDB" id="2146116at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1540.10">
        <property type="entry name" value="Rhomboid-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002610">
        <property type="entry name" value="Peptidase_S54_rhomboid-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022764">
        <property type="entry name" value="Peptidase_S54_rhomboid_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035952">
        <property type="entry name" value="Rhomboid-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22936:SF69">
        <property type="entry name" value="RHOMBOID-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22936">
        <property type="entry name" value="RHOMBOID-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01694">
        <property type="entry name" value="Rhomboid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144091">
        <property type="entry name" value="Rhomboid-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 10" id="KW-0645">Protease</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 10" id="KW-0720">Serine protease</keyword>
    <keyword evidence="5 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="171"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="277"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="309"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="333"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="366"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="388"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="417"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S54 rhomboid" evidence="12">
        <location>
            <begin position="268"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="34"/>
            <end position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009045"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU362115"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF01694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="OBZ90790.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="468" mass="50982" checksum="09639D0FE8A26A89" modified="2016-11-30" version="1">MAGSIKEDSTKENTTHFAEDGFTSPITAHTPLPSDDKPTSPLDDKSSLASPRENQGKLEIDSTNYGPTFKEELGNHYDPSAVPATSALLTSGFAPPSSDEKSVPYHEASSVPPPPLHTEQRRVDTFVQRMKGYQQPNDLEGQFKAFPRSAPNDNRSFKGLLYRQICGGSRFATFTYTTAIIMIGVFIYELVRNNQLTGSVIQTSPSFNPMIGPNYMVLINMGSRFNPCMRTMSSWTPTTAVSNCYTSDSTCTVESLCGFGGFNGVTPNQTFRFFTSIFLHGGVVHILMNMITHFSLGSDVERTLGTPRYALLYLGSGVFGFVLSALLAGPTVSSMGCSGALFGIVGFTVIDLLFRWRQTRRPGRELCQLVFVVVISLVLGLLPGLDNFAHIGGLVMGLLIGTLISTVRSESSPRAKILAWSSKLVSLVLIVVLFIVCLRAFYNTSDLSTVCPNCKYLSCLPVNGWCDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NPM7</accession>
    <name>A0A1C7NPM7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_00877</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000023">
        <property type="protein sequence ID" value="OBZ91072.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NPM7"/>
    <dbReference type="STRING" id="101091.A0A1C7NPM7"/>
    <dbReference type="InParanoid" id="A0A1C7NPM7"/>
    <dbReference type="OrthoDB" id="2414723at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.80">
        <property type="entry name" value="Phosphotransferase system, lactose/cellobiose-type IIA subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036181">
        <property type="entry name" value="MIT_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF116846">
        <property type="entry name" value="MIT domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="21"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="369"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="375"/>
            <end position="393"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ91072.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="393" mass="43507" checksum="67454A165B11DA93" modified="2016-11-30" version="1">MASFVSSILHSSANKIERTILGSGKKDSGTRSGFHASNGPSLYHPSQMNCNTEPISAPPPYDTMHPTVLTSPIPTPSTSWTSEMSALAEKIKDDVTNTLKGNSKSNQQQVDRYGISQGMKLVSIAADEYEGGNESVALNLYLTGVDKILMALPNKTDLNTKRAIREKLQSVEERVGILNLASSEKKLAQQQKGNPTDSSDTRQSTLNTYILSHLASAISTFSGKAYQTTMPEEPDDNVVRSKAGYDSHHVTTTTNQSERDSMVQFKRLGQYITDFTVTTAVLIKQSPLPDLISYLLNCLYQLLLWADSQYHIIQKLRNASVHFVKLGLQADEKYRIHEYLSEGVYMFMTAGLKAAVAFKEAPGHKDLIEPEPTRCSPQAPQKARTSWLWTSRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NPQ6</accession>
    <name>A0A1C7NPQ6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">ATP-dependent DNA helicase</fullName>
            <ecNumber evidence="1">5.6.2.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">pif1_1</name>
        <name evidence="4" type="ORF">A0J61_01527</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="5.6.2.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the helicase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.6.2.3" evidence="1"/>
    <dbReference type="EMBL" id="LUGH01000049">
        <property type="protein sequence ID" value="OBZ90426.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NPQ6"/>
    <dbReference type="STRING" id="101091.A0A1C7NPQ6"/>
    <dbReference type="InParanoid" id="A0A1C7NPQ6"/>
    <dbReference type="OrthoDB" id="3691720at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043139">
        <property type="term" value="F:5'-3' DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000723">
        <property type="term" value="P:telomere maintenance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd18809">
        <property type="entry name" value="SF1_C_RecD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010285">
        <property type="entry name" value="DNA_helicase_pif1-like_DEAD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049163">
        <property type="entry name" value="Pif1-like_2B_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10492">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10492:SF95">
        <property type="entry name" value="HELITRON HELICASE-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05970">
        <property type="entry name" value="PIF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21530">
        <property type="entry name" value="Pif1_2B_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0227">DNA damage</keyword>
    <keyword evidence="1" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="1" id="KW-0234">DNA repair</keyword>
    <keyword evidence="1 4" id="KW-0347">Helicase</keyword>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA helicase Pif1-like DEAD-box helicase" evidence="2">
        <location>
            <begin position="2"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="domain" description="DNA helicase Pif1-like 2B" evidence="3">
        <location>
            <begin position="194"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU363044"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF05970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF21530"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OBZ90426.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="342" mass="38527" checksum="D885E1C82397DC64" modified="2016-11-30" version="1" fragment="single">NALCNYFRSQEEIVLCVASSGIASLLLSGGCTSHFRFKMPIAINETSFCYITKKGHLADLLRSITLIIWDEVPMQNKLCFGAVDRSLKDICSSDKLLGSIPVVLGEDFVQIPPVIRNVEKLISKIHPKQDLDRSLENPHFFFKSAVLTTQNSVVDSLNEMVLDLMPRDSITLLSADTADTSEQENDEIHRLAPEYLQTLNPPSFPPAKLTLKKGCIVMFLRNLNSQKGLFSVLHEDGSGNKQIEVIPRVQLSILEDEYPFILTRKQFPVRLSFAMTINKVQGQSLENVGIDLRNPTFTHRQLYVALSRSTNLKGIRILHQPNSDNTNYSKIENIIYPELLLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NQE3</accession>
    <name>A0A1C7NQE3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Nitrogen assimilation transcription factor nit-4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">nit-4_3</name>
        <name evidence="9" type="ORF">A0J61_02459</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000093">
        <property type="protein sequence ID" value="OBZ89484.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NQE3"/>
    <dbReference type="STRING" id="101091.A0A1C7NQE3"/>
    <dbReference type="InParanoid" id="A0A1C7NQE3"/>
    <dbReference type="OrthoDB" id="3362851at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050815">
        <property type="entry name" value="TF_fung"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47338:SF5">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47338">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="8">
        <location>
            <begin position="4"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="172"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="659"/>
            <end position="692"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="768"/>
            <end position="897"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="46"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="178"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="659"/>
            <end position="676"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="681"/>
            <end position="692"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="792"/>
            <end position="802"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="824"/>
            <end position="835"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="856"/>
            <end position="865"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="874"/>
            <end position="890"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OBZ89484.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="903" mass="103845" checksum="A14296B400E3F8CA" modified="2016-11-30" version="1">MTMACERCRSKKVKCDFAHPQCGRCQQAKVECSYDGSATQIDLFNLVKLNETVDLLQKRVQSIESDIKDVCNNTQYVANEIRVNRESSNEKNKEKEIVEEEDSLQQKPDIAPVIQRNTSNINRLMAATASQWSLSLTSKGLRIDTNIASLHDLYDILLSGMSQFDFPPNLHDSAHLDTSSQSSSSTSGCDSPNMETVTMKKRKPLWKTRIKAFPLYSSWGPDDHRHDTNTKRNDTQQDDDIKAVEDIPYEVLRSMIGIYEQCFLCFPCYNPNNSVAVRFKNGTLDPLLANSIFAWTARHAAIYHNLFPGKDPNRVGHSFFLNAKFLVKERFMKTSVDTMHSLLIMYIYAIGIPSRQKVEVESEAYIYLGLAIRMCLDLKMNMESKSKDIYEQESHRRFFWSLHFLETLGSIHSDRPFALPPDNTITTEFPTVMKHEEAEEEKRYQVEFMIQRYRITRIYRDIIWKTTEEKPLFSHISALDKQLQNWHHALPDYLKFKPGDIHKRNWSSTSFREQACIKLNFEYNFQLCQLYSLFLSRPEEHVREESSTVEVLSRDICLKAANNTVELLECWIQLKQLWCHFSLETLMMATHIYGSILSQPENNNPQQKETIQANLKKIANILANSPVRHHHYVITLVNRIKSIFKETLHMDLYLEDANRQQGPSSQSSVRSTTTDSAVHLSPSTQPSCSSHSIVHSYTPPHLAVNNTNTSLSLGSDQFNPRMLNLFGTHPPVSHFDMHFSDFVYTPTVLDYAGPIDQANLITPHARNYTENDKKPFNPYVPQQGHHFEHSTMYPSNTSSSHPNLPFQPLRHSAEHQRTQHHPKQNQPSPLASTSWVPLHPPNPSSQPMMMDHSQESYYSPHHLSPSQPPPPPSSTSSQSPSQNSSSSNRSKGFYHNYDHIYYQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NQK0</accession>
    <name>A0A1C7NQK0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Transcription initiation factor TFIID subunit 4</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">TBP-associated factor 4</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">A0J61_00586</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Functions as a component of the DNA-binding general transcription factor complex TFIID. Binding of TFIID to a promoter (with or without TATA element) is the initial step in pre-initiation complex (PIC) formation. TFIID plays a key role in the regulation of gene expression by RNA polymerase II through different activities such as transcription activator interaction, core promoter recognition and selectivity, TFIIA and TFIIB interaction, chromatin modification (histone acetylation by TAF1), facilitation of DNA opening and initiation of transcription.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TAF4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000013">
        <property type="protein sequence ID" value="OBZ91387.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NQK0"/>
    <dbReference type="STRING" id="101091.A0A1C7NQK0"/>
    <dbReference type="InParanoid" id="A0A1C7NQK0"/>
    <dbReference type="OrthoDB" id="21060at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005669">
        <property type="term" value="C:transcription factor TFIID complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046982">
        <property type="term" value="F:protein heterodimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016251">
        <property type="term" value="F:RNA polymerase II general transcription initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006367">
        <property type="term" value="P:transcription initiation at RNA polymerase II promoter"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd08045">
        <property type="entry name" value="HFD_TAF4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.20.10">
        <property type="entry name" value="Histone, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009072">
        <property type="entry name" value="Histone-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045144">
        <property type="entry name" value="TAF4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007900">
        <property type="entry name" value="TAF4_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15138">
        <property type="entry name" value="TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15138:SF14">
        <property type="entry name" value="TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05236">
        <property type="entry name" value="TAF4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="4" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Transcription initiation factor TFIID component TAF4 C-terminal" evidence="10">
        <location>
            <begin position="450"/>
            <end position="583"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="108"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="319"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="367"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="586"/>
            <end position="617"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="14"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="142"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="158"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="325"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="367"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="9">
        <location>
            <begin position="401"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="586"/>
            <end position="600"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006178"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00017306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00025346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00031747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF05236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="OBZ91387.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="655" mass="72884" checksum="D6EB571E8ED68A65" modified="2016-11-30" version="1">MPVDGEDSNEPNASSQNSQQQQIPHQDLNFSLSDLLSNNHDVNDSSFQSIVQTLSNNSDEQHIAPSYAHLPAELQDLFNTNETDDLLSVQGSNADASSILQGDMLWHQQQPFVPPPPPQQQQQPNNTLTLQPNSSPVPNPSTPTTVLSPSPFHSVQLPSQSSPSISPIQQQQQQQASPTTLLDNITAQLPPDRKDMFIQLFRELQTNQVSAQQFLSKAKNLLGQQEYQQLEDLKNKPAQFKSSIDEENRKRALLHSPIKSEDLQTSANIPQLKRVKTEHIPMFSQQQQQQQQLQQLQMQLQQQHQMQIAQAQAQAQAQAQAQAQKTPRQTNKTPKQAQPVLPPSPSPLQPNTTIATPSVQIAQPTVFKTPTVPATPTLQVPTKTNLVTPSKTASPSNDNTLPPPPLPNTMPTPNTPSAEPVNPTVTVTNNNNSGSGGGSGGDSRIDYDTLTDVMGYAGVDLKEEAEHFMREEENIANLLPDGVDRSKAQDFMNTDMLRTKVLSYAKHVNIKEIDSDFLSYLALATQDRVRTVLEAMVAASKHRTFDPFRKPPTENGHPLFKIQLKQHVTSQLKAIERVERQIELDLDPVEESEEESESEEPGWYSTRSKKPLQSITSSDRKVTVQDAIFVMERDVQGGRGTNQRTLLKAYNEWLY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NQW5</accession>
    <name>A0A1C7NQW5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_00426</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000009">
        <property type="protein sequence ID" value="OBZ91535.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NQW5"/>
    <dbReference type="InParanoid" id="A0A1C7NQW5"/>
    <dbReference type="OrthoDB" id="3599883at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024368">
        <property type="entry name" value="Ecl1/2/3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12855">
        <property type="entry name" value="Ecl1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ91535.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="120" mass="13553" checksum="2E42BBD9AC56D6CA" modified="2016-11-30" version="1">MDLSWCIICDNRVDDVLNESSLYCSESCQLKDQMKSITNQLAINQQQQQQQQQQKKLMLSSKPIASLRNKRPAAPSASYPWVPLYRRRRGVVVSKRCQPVVASSFTTANALFSSNKSTLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NQX4</accession>
    <name>A0A1C7NQX4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 16">Peroxisome assembly protein 12</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="14 16">Peroxin-12</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="19" type="primary">PEX12</name>
        <name evidence="19" type="ORF">A0J61_00442</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="19 20" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19 20">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="16">Component of a retrotranslocation channel required for peroxisome organization by mediating export of the PEX5 receptor from peroxisomes to the cytosol, thereby promoting PEX5 recycling.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="subunit">
        <text evidence="15">Component of the PEX2-PEX10-PEX12 retrotranslocation channel, composed of PEX2, PEX10 and PEX12.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Peroxisome membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 16">Belongs to the pex2/pex10/pex12 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="19">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000010">
        <property type="protein sequence ID" value="OBZ91502.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NQX4"/>
    <dbReference type="FunCoup" id="A0A1C7NQX4">
        <property type="interactions" value="258"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NQX4"/>
    <dbReference type="InParanoid" id="A0A1C7NQX4"/>
    <dbReference type="OrthoDB" id="107372at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990429">
        <property type="term" value="C:peroxisomal importomer complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005778">
        <property type="term" value="C:peroxisomal membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004842">
        <property type="term" value="F:ubiquitin-protein transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016562">
        <property type="term" value="P:protein import into peroxisome matrix, receptor recycling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006513">
        <property type="term" value="P:protein monoubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd16451">
        <property type="entry name" value="mRING_PEX12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017375">
        <property type="entry name" value="PEX12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006845">
        <property type="entry name" value="Pex_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12888:SF0">
        <property type="entry name" value="PEROXISOME ASSEMBLY PROTEIN 12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12888">
        <property type="entry name" value="PEROXISOME ASSEMBLY PROTEIN 12 PEROXIN-12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04757">
        <property type="entry name" value="Pex2_Pex12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF038074">
        <property type="entry name" value="Peroxisome_assembly_p12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12 16" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13 16" id="KW-0576">Peroxisome</keyword>
    <keyword evidence="10" id="KW-0653">Protein transport</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <keyword evidence="9" id="KW-0862">Zinc</keyword>
    <keyword evidence="8" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Pex N-terminal" evidence="18">
        <location>
            <begin position="24"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="293"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="17">
        <location>
            <begin position="299"/>
            <end position="312"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004585"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008704"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00018980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00029692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00034505"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PIRNR" id="PIRNR038074"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="Pfam" id="PF04757"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="OBZ91502.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="382" mass="43972" checksum="4BE1215C1E7D72E4" modified="2016-11-30" version="1">MEFMSALGSQEDAYRPSLFELVAQEKLRELLQPAVQYILAIYAQRYPRLLIKIVNNHEEFYALLMLLIERHYLKEWGGSFAENFYGLKRVSSTRSDRIRFNAPVNSGSSPSLTQREIIKSLLILVGLPYVKSKLDLLYQKTSGGAASSILGDNEQEELEIEQLASAETSQTTKWMIRLKRLFKKIYPLLNLLFYGSNLCYHVAYLFDKTRYYTPWLHLAGIEVKRMSMQDYRTYYDKTAGPASNTSSFSLRHPLHTLSIVSSKVIEFLKVLLPMSIFFFKFLEWWYSSEFSRNNTSQEGDEKIIPPPEKIKPDPNGIELPVTPNTCPLCKTNPINNPTALPSGYVFCYTCVYHHVQEHGRCPVSLIKVNPDNQLTKLYADVM</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NQY2</accession>
    <name>A0A1C7NQY2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Small ribosomal subunit protein mS33</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">RSM27</name>
        <name evidence="8" type="ORF">A0J61_00506</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the mitochondrion-specific ribosomal protein mS33 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000011">
        <property type="protein sequence ID" value="OBZ91438.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NQY2"/>
    <dbReference type="STRING" id="101091.A0A1C7NQY2"/>
    <dbReference type="InParanoid" id="A0A1C7NQY2"/>
    <dbReference type="OrthoDB" id="2257454at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013219">
        <property type="entry name" value="Ribosomal_mS33"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13362">
        <property type="entry name" value="MITOCHONDRIAL RIBOSOMAL PROTEIN S33"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13362:SF2">
        <property type="entry name" value="SMALL RIBOSOMAL SUBUNIT PROTEIN MS33"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08293">
        <property type="entry name" value="MRP-S33"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 8" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="79"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="81"/>
            <end position="103"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00035132"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OBZ91438.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="103" mass="11706" checksum="66876FB038F92BD8" modified="2016-11-30" version="1">MSQPASRLAQLTQLSCKVFSNVYNPTSARTGNKILRQRLFGSTLTGYHPQKLVHFRDIQALYPQLGLVDLEEKERLDEIARRKRRGKGAPKKGQGKRASNKKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NR37</accession>
    <name>A0A1C7NR37_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_00498</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000011">
        <property type="protein sequence ID" value="OBZ91430.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NR37"/>
    <dbReference type="STRING" id="101091.A0A1C7NR37"/>
    <dbReference type="InParanoid" id="A0A1C7NR37"/>
    <dbReference type="OrthoDB" id="2412648at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008889833" evidence="1">
        <location>
            <begin position="19"/>
            <end position="162"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ91430.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="162" mass="16844" checksum="C0E34C6814FE1F32" modified="2016-11-30" version="1">MYFTLALLLAASVATVSASATGCNPSYNVTGSGSCFTNCNTQAGSAYLSGWTMDPDSPLFIKSLSVMCNKGTPEYLAFMTKAGMCMVNCPDDPALFNNEFSGACSWYSQHKNDTCTVSNASSTATNSSSVSVAKEASSAEVKQVQYGAALLLTLAGTGLLIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NR63</accession>
    <name>A0A1C7NR63_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_02210</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000080">
        <property type="protein sequence ID" value="OBZ89744.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NR63"/>
    <dbReference type="InParanoid" id="A0A1C7NR63"/>
    <dbReference type="OrthoDB" id="5576441at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ89744.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="256" mass="29101" checksum="7EDAE56ED466E432" modified="2016-11-30" version="1">MTNSLEREGSYILYQLTRTLTPEPISCHTCRKKEDKIDIQQCLKKDLSPQTYLKLALILSNNGSNVDLDNSREDVVLLGNFATLIAEDSTFALLLIERLYLLCSEHEGLDTIQIISQLLGKSDEFHKYRELEFIKLLRQEMKPSTIQQIKQQVEAKAVQLDRLVVSDIKLARLIPLLGAVYGSPNSLYDMSFFRQDSLTIISDVVNQQPELAERAQSYEEDSQSSQTNICDYLPDVDDNEHLILSLPLDSSTSDIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NRC1</accession>
    <name>A0A1C7NRC1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Rieske domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">A0J61_00474</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000010">
        <property type="protein sequence ID" value="OBZ91479.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NRC1"/>
    <dbReference type="InParanoid" id="A0A1C7NRC1"/>
    <dbReference type="OrthoDB" id="426882at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.102.10.10">
        <property type="entry name" value="Rieske [2Fe-2S] iron-sulphur domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017941">
        <property type="entry name" value="Rieske_2Fe-2S"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036922">
        <property type="entry name" value="Rieske_2Fe-2S_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00355">
        <property type="entry name" value="Rieske"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50022">
        <property type="entry name" value="ISP domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51296">
        <property type="entry name" value="RIESKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0001">2Fe-2S</keyword>
    <keyword evidence="3" id="KW-0408">Iron</keyword>
    <keyword evidence="4" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rieske" evidence="6">
        <location>
            <begin position="39"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OBZ91479.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="144" mass="16305" checksum="2E2203F7D09B15C7" modified="2016-11-30" version="1">MFEPTIKYRRVNESSEAPQDIPVQAKATTPEPETQTESKYDFTFEEEKETKIEADPNDESRIIITLSTGKKYSADRYCPHAGADLTYHGRIGEHDYPPEIGPILMCSIHYWEFPLEKGGSGLTSLNACPMDSTTSCPLEKKLEW</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NRD2</accession>
    <name>A0A1C7NRD2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Ent-kaurene oxidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">CYP503A1_0</name>
        <name evidence="7" type="ORF">A0J61_00454</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 5">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000010">
        <property type="protein sequence ID" value="OBZ91489.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NRD2"/>
    <dbReference type="STRING" id="101091.A0A1C7NRD2"/>
    <dbReference type="InParanoid" id="A0A1C7NRD2"/>
    <dbReference type="OrthoDB" id="1844152at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11041">
        <property type="entry name" value="CYP503A1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002403">
        <property type="entry name" value="Cyt_P450_E_grp-IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46206">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46206:SF7">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00465">
        <property type="entry name" value="EP450IV"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0349">Heme</keyword>
    <keyword evidence="4 5 6" id="KW-0408">Iron</keyword>
    <keyword evidence="3 5 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" description="axial binding residue" evidence="5">
        <location>
            <position position="485"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR602403-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OBZ91489.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="538" mass="60808" checksum="B1201D4A81B495A3" modified="2016-11-30" version="1">MLTGAAKNTITTIANYWQDNSEWVAQNIPLTKKQCTSLSIAATITYITWKLYKSKTTDRYGSNASNLPPMVKGAMPIYGHLLELQKDPAKFVDEAKETYGPCFRISVPGLGTVAVVSELLISEVMKSGKNFSFNKGIEKVFPSEKIVELSYKHKYDAYKISTREKHPVIYPIKHNFKEHQIDLFTERIVKAFEVGLKKHLNLKKGEQKEIDVRPIISLIVADISCACFAGSQATKNDELIRSMAEFTTKLIKVSALWTLLPTWLGEIVVRRFYSVEREMDQIMNELVPHLRKVQNGEFGNDYEKTFATMVLEIPREDGSLRSPEDAAYRFNGIALASIHTTSHFTAFALHELAPRPELIQALRDELAPLGNDRTPETVSKLPLMESFFRELLRHNADYLGLHHVALQDTVLSSGHFIPKGTMVVLSVHQMHRNLRFLPVDETTGEPVAGDSPLDVFDAYRYYNKNVKSTTVGVEFLPFGMGAHACPGRFFAANEIKYIIAEIICRFNIKTKTGHRAKDNIFIGMTRFPPSEKLIFEAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NRL6</accession>
    <name>A0A1C7NRL6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">RAD50-interacting protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">Rint1</name>
        <name evidence="2" type="ORF">A0J61_00287</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000006">
        <property type="protein sequence ID" value="OBZ91658.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NRL6"/>
    <dbReference type="STRING" id="101091.A0A1C7NRL6"/>
    <dbReference type="InParanoid" id="A0A1C7NRL6"/>
    <dbReference type="OrthoDB" id="407410at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070939">
        <property type="term" value="C:Dsl1/NZR complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006888">
        <property type="term" value="P:endoplasmic reticulum to Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0060628">
        <property type="term" value="P:regulation of ER to Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006890">
        <property type="term" value="P:retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.1420">
        <property type="entry name" value="Dsl1p vesicle tethering complex, Tip20p subunit, domain B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.670">
        <property type="entry name" value="Dsl1p vesicle tethering complex, Tip20p subunit, domain D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042044">
        <property type="entry name" value="EXOC6PINT-1/Sec15/Tip20_C_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007528">
        <property type="entry name" value="RINT1_Tip20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042042">
        <property type="entry name" value="Tip20p_domB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13520:SF0">
        <property type="entry name" value="RAD50-INTERACTING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13520">
        <property type="entry name" value="RAD50-INTERACTING PROTEIN 1 RINT-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04437">
        <property type="entry name" value="RINT1_TIP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51386">
        <property type="entry name" value="RINT1_TIP20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="33"/>
            <end position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ91658.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="787" mass="91198" checksum="D9412C0DC4003B0F" modified="2016-11-30" version="1">MTHSIVADDLQQFLADTIKSEHDLNLEHLQTLLDARQKEQKALDSQLSSLKDETKSILETRLKQAKQHHVTLEELSSSIETTEQAVDQAITLNQTNSDFFNELSMIEQKLRTVDHARTYLKTLLLASELSSQALSYVQTSPEKAMTPYVQLVQLEQYIHQQSIQQPHYDSLHVHVKKTQQRLSEELEAILVKNFKTVLDDIGWPTQIKPPYGPQLKSKLGAFKAAFHHLIQLQKSTEGQVQQDVLLIPVVLMLDGLSLRFRFHFEGSKPTNRADKPEWYLAHTKNTIASHIPFIMTTIQPILDKQDNVSIKDQFIQGFLVNVDRKLQKSMPQLMAHPNWLSHTMHELLEFDKALVEEFAYRYPYALSQKVTENSTWFQAWFQAEKSFAQSRYDDIMLDREAFDVYAEDAFVGDQQPSKQDIPRTKSAVRLVNLLENITAAYQLVPGLHQKLMFFVHIQLNLIGQYQKRLSTAIDSFEALSLIRSVPVPGALPEAVTGVMTSNEKDGTVSALYRLHRWWTSARSMRDVLKDWNEDDFFLELQLQFNQYPEAIQQVVDRMPLQERNNCMLNLAHHQTDNIFSDALTAFDQLIKRIEKIIVKIALKEWSADARKYAKRDAWWQSSESANSYEDISDELYKPLQDLRMTLNYLHRTLPQPEFLSLFRQLMKEIEEWYWKNVITASQFSGAGALQLETDIKFGLWKIGQRWVNKPENYTKRLKEAIQLLTLPFEQQSGTDSSSCGDLMRALSDTSQLEFIQKMLDKLGIEVLSNGQIRDVLRRRNDMLYSWS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NRP0</accession>
    <name>A0A1C7NRP0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">chitinase</fullName>
            <ecNumber evidence="3">3.2.1.14</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">chiB_1</name>
        <name evidence="11" type="ORF">A0J61_00269</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Random endo-hydrolysis of N-acetyl-beta-D-glucosaminide (1-&gt;4)-beta-linkages in chitin and chitodextrins.</text>
            <dbReference type="EC" id="3.2.1.14"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the glycosyl hydrolase 18 family. Chitinase class V subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.14" evidence="3"/>
    <dbReference type="EMBL" id="LUGH01000005">
        <property type="protein sequence ID" value="OBZ91688.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NRP0"/>
    <dbReference type="STRING" id="101091.A0A1C7NRP0"/>
    <dbReference type="InParanoid" id="A0A1C7NRP0"/>
    <dbReference type="OrthoDB" id="76388at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008061">
        <property type="term" value="F:chitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008843">
        <property type="term" value="F:endochitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006032">
        <property type="term" value="P:chitin catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000272">
        <property type="term" value="P:polysaccharide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06548">
        <property type="entry name" value="GH18_chitinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.50.10:FF:000005">
        <property type="entry name" value="Endochitinase B1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.50.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011583">
        <property type="entry name" value="Chitinase_II/V-like_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029070">
        <property type="entry name" value="Chitinase_insertion_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001223">
        <property type="entry name" value="Glyco_hydro18_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001579">
        <property type="entry name" value="Glyco_hydro_18_chit_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050314">
        <property type="entry name" value="Glycosyl_Hydrlase_18"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11177">
        <property type="entry name" value="CHITINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11177:SF317">
        <property type="entry name" value="CHITINASE 12-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00704">
        <property type="entry name" value="Glyco_hydro_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00636">
        <property type="entry name" value="Glyco_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54556">
        <property type="entry name" value="Chitinase insertion domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01095">
        <property type="entry name" value="GH18_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51910">
        <property type="entry name" value="GH18_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="5" id="KW-0146">Chitin degradation</keyword>
    <keyword evidence="7 9" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="4 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GH18" evidence="10">
        <location>
            <begin position="1"/>
            <end position="343"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000822"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU000489"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="OBZ91688.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="366" mass="42128" checksum="8A259B17E38E162A" modified="2016-11-30" version="1">MTTPPPSTNGPVIAGYFSNWQDSYADKEIHFPANECIDGKADSWDDQGNNLYGNFKQFYLLKQRYRHLKVSISIGGWTWSKNFGGVVCDSEKRQRFVESSVKLVSDFGLDGIDIDWEYPKNDKEALHYVHLLYDIRIALDKYQEECGQLSQPRLLLTVAVPCGPENYRKLRLADMEPYVDLFYLMAYDYAGSWDEKTGHQAAMFGGALNTEQAVNDYLKFVPSRKLVVGLPMYGRGFSDTDGPDSPYNGVPKGTWEEGQFDYRDLPKPGATEYYDHQKIASWSYDSNTREFISYDNPQAIAAKCNYVQQRQLGGCMFWELSGDQHHHNPRNLVNTVYRSFDGQIDQITNHLDYPKSQFDNLRNYMK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NRX0</accession>
    <name>A0A1C7NRX0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_00245</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000005">
        <property type="protein sequence ID" value="OBZ91679.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NRX0"/>
    <dbReference type="STRING" id="101091.A0A1C7NRX0"/>
    <dbReference type="InParanoid" id="A0A1C7NRX0"/>
    <dbReference type="OrthoDB" id="2287482at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="41"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="147"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="280"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="55"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="147"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="170"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="182"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="198"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="299"/>
            <end position="313"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ91679.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="374" mass="42937" checksum="306453F5826972C5" modified="2016-11-30" version="1">MPATSTTTVVAMLPASNPITIPGQMDTELSYREIIKQLAAQTTTKPYGDIPPMLSKRKKKRVRKEKQPIPSERAKPIRRMSHVEDWIQVDSKESLPDEEELVQSPFRNFLSADFFTEVLPLHMPPPSLSEKYQIEEQVGQVERLDDMLDDSEEDEDEDEDEEEESEEERYDLPLKKNENHKSISKSLHHKSLLRRHSISSFTQKSSPTSSTTTASYPISSSPPHLSNTDHTLWKATLAKLKQSLLLVTQPSPSLNSVTKQEKATADETLVAKNKKRTNKLIPMPIPPRRPLSQKRRSEATTQPRFNPDTNTYTRDTRSNPDHLRMISAELNMMRGRKLLSPLKPRGFLPRRKDPFIRGEHRRPSNLIQEITFSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NRY4</accession>
    <name>A0A1C7NRY4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Protein SDS23</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">SDS23_1</name>
        <name evidence="5" type="ORF">A0J61_00130</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000003">
        <property type="protein sequence ID" value="OBZ91778.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NRY4"/>
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        <property type="interactions" value="37"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NRY4"/>
    <dbReference type="InParanoid" id="A0A1C7NRY4"/>
    <dbReference type="OrthoDB" id="449052at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004865">
        <property type="term" value="F:protein serine/threonine phosphatase inhibitor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042149">
        <property type="term" value="P:cellular response to glucose starvation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02205">
        <property type="entry name" value="CBS_pair_SF"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.580.10">
        <property type="entry name" value="CBS-domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050511">
        <property type="entry name" value="AMPK_gamma/SDS23_families"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000644">
        <property type="entry name" value="CBS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046342">
        <property type="entry name" value="CBS_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13780">
        <property type="entry name" value="AMP-ACTIVATED PROTEIN KINASE, GAMMA REGULATORY SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13780:SF36">
        <property type="entry name" value="CBS DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00571">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="4"/>
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        <property type="entry name" value="CBS"/>
        <property type="match status" value="4"/>
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        <property type="entry name" value="CBS"/>
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    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0129">CBS domain</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="CBS" evidence="4">
        <location>
            <begin position="22"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="4">
        <location>
            <begin position="135"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="4">
        <location>
            <begin position="210"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="4">
        <location>
            <begin position="289"/>
            <end position="348"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OBZ91778.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="354" mass="39022" checksum="91D5B8AE4E5AA142" modified="2016-11-30" version="1">MAHREGITTSPSDWTLVKASSLIKDQKVITIDGSLPVEEACNVLIDNNISSAPVYDNTETSRTPIVHAKSYVGMFDYGDVIAYILLVLQNMPTPPPGLSDEGIKHDLDNMTFEIKDIVRRAHEGQQVPVKLASDLSEKNPFYSIMPEATLLSAVEEFAYGAHRVCVLNHDGSIKGILSQSVVAKYLYENQRHFPEIEIVMNKTLRQLGLGVSDVISVNADSPVLHALALMSKHAISSVAVLGHMGVVLGNISLTDVKHVMKSYHHQLLWKTCFQFVGMIRIQQGIDDGQDRLPVFDVRLDTTLGFAVAKLLATKSHRVWVIDEKERAIGVVSITDVMRAIASTTGIEINNTNKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NRY9</accession>
    <name>A0A1C7NRY9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="24">Glutamate synthase [NADH]</fullName>
            <ecNumber evidence="8">1.4.1.13</ecNumber>
            <ecNumber evidence="20">1.4.1.14</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="30" type="primary">glt1_1</name>
        <name evidence="30" type="ORF">A0J61_00785</name>
    </gene>
    <organism evidence="30 31">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="30 31" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="30 31">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="23">Forms L-glutamate from L-glutamine and 2-oxoglutarate. Represents an alternative pathway to L-glutamate dehydrogenase for the biosynthesis of L-glutamate. Participates with glutamine synthetase in ammonia assimilation processes. The enzyme is specific for NADH, L-glutamine and 2-oxoglutarate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="22">
            <text>2 L-glutamate + NAD(+) = L-glutamine + 2-oxoglutarate + NADH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13753"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="EC" id="1.4.1.14"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="21">
            <text>2 L-glutamate + NADP(+) = L-glutamine + 2-oxoglutarate + NADPH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:15501"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="EC" id="1.4.1.13"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="26">
            <name>[3Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:21137"/>
        </cofactor>
        <text evidence="26">Binds 1 [3Fe-4S] cluster.</text>
    </comment>
    <comment type="pathway">
        <text evidence="5">Amino-acid biosynthesis; L-glutamate biosynthesis via GLT pathway; L-glutamate from 2-oxoglutarate and L-glutamine (NAD(+) route): step 1/1.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3">Energy metabolism; nitrogen metabolism.</text>
    </comment>
    <comment type="pathway">
        <text evidence="4">Nitrogen metabolism.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Homotrimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the glutamate synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="30">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.4.1.13" evidence="8"/>
    <dbReference type="EC" id="1.4.1.14" evidence="20"/>
    <dbReference type="EMBL" id="LUGH01000020">
        <property type="protein sequence ID" value="OBZ91166.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="FunCoup" id="A0A1C7NRY9">
        <property type="interactions" value="193"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NRY9"/>
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    <dbReference type="OrthoDB" id="4327079at2759"/>
    <dbReference type="UniPathway" id="UPA00045"/>
    <dbReference type="UniPathway" id="UPA00634">
        <property type="reaction ID" value="UER00690"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051538">
        <property type="term" value="F:3 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016040">
        <property type="term" value="F:glutamate synthase (NADH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004355">
        <property type="term" value="F:glutamate synthase (NADPH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016639">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019676">
        <property type="term" value="P:ammonia assimilation cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097054">
        <property type="term" value="P:L-glutamate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd00982">
        <property type="entry name" value="gltB_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00713">
        <property type="entry name" value="GltS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd02808">
        <property type="entry name" value="GltS_FMN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.50.50.60:FF:000207">
        <property type="entry name" value="Glutamate synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1060.10:FF:000006">
        <property type="entry name" value="Glutamate synthase (NADPH/NADH)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.70:FF:000031">
        <property type="entry name" value="Glutamate synthase 1 [NADH]"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.70:FF:000017">
        <property type="entry name" value="Glutamate synthase [NADH], amyloplastic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000113">
        <property type="entry name" value="Glutamate synthase [NADH], amyloplastic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.50.50.60:FF:000124">
        <property type="entry name" value="Glutamate synthase small subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.160.20.60:FF:000001">
        <property type="entry name" value="Glutamate synthase, large subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.20.10:FF:000001">
        <property type="entry name" value="Glutamate synthase, large subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1060.10">
        <property type="entry name" value="Alpha-helical ferredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.20.60">
        <property type="entry name" value="Glutamate synthase, alpha subunit, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.10">
        <property type="entry name" value="Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017896">
        <property type="entry name" value="4Fe4S_Fe-S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028261">
        <property type="entry name" value="DPD_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023753">
        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017932">
        <property type="entry name" value="GATase_2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002489">
        <property type="entry name" value="Glu_synth_asu_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036485">
        <property type="entry name" value="Glu_synth_asu_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006982">
        <property type="entry name" value="Glu_synth_centr_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012220">
        <property type="entry name" value="Glu_synth_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002932">
        <property type="entry name" value="Glu_synthdom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006005">
        <property type="entry name" value="Glut_synth_ssu1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051394">
        <property type="entry name" value="Glutamate_Synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009051">
        <property type="entry name" value="Helical_ferredxn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01317">
        <property type="entry name" value="GOGAT_sm_gam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF008730">
        <property type="entry name" value="PRK11750.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43100">
        <property type="entry name" value="GLUTAMATE SYNTHASE [NADPH] SMALL CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43100:SF1">
        <property type="entry name" value="GLUTAMATE SYNTHASE [NADPH] SMALL CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14691">
        <property type="entry name" value="Fer4_20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00310">
        <property type="entry name" value="GATase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04898">
        <property type="entry name" value="Glu_syn_central"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01645">
        <property type="entry name" value="Glu_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01493">
        <property type="entry name" value="GXGXG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000187">
        <property type="entry name" value="GOGAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00419">
        <property type="entry name" value="ADXRDTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69336">
        <property type="entry name" value="Alpha subunit of glutamate synthase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46548">
        <property type="entry name" value="alpha-helical ferredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51395">
        <property type="entry name" value="FMN-linked oxidoreductases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="N-terminal nucleophile aminohydrolases (Ntn hydrolases)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51971">
        <property type="entry name" value="Nucleotide-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51379">
        <property type="entry name" value="4FE4S_FER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51278">
        <property type="entry name" value="GATASE_TYPE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="19 26" id="KW-0003">3Fe-4S</keyword>
    <keyword evidence="9" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="13" id="KW-0274">FAD</keyword>
    <keyword evidence="10" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="11" id="KW-0288">FMN</keyword>
    <keyword evidence="18" id="KW-0314">Glutamate biosynthesis</keyword>
    <keyword evidence="14" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="16" id="KW-0408">Iron</keyword>
    <keyword evidence="17 26" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="12" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="15" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="31" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glutamine amidotransferase type-2" evidence="28">
        <location>
            <begin position="26"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="29">
        <location>
            <begin position="1595"/>
            <end position="1630"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="27">
        <location>
            <begin position="924"/>
            <end position="945"/>
        </location>
    </feature>
    <feature type="active site" description="For GATase activity" evidence="25">
        <location>
            <position position="26"/>
        </location>
    </feature>
    <feature type="binding site" evidence="26">
        <location>
            <position position="1145"/>
        </location>
        <ligand>
            <name>[3Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:21137"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="26">
        <location>
            <position position="1151"/>
        </location>
        <ligand>
            <name>[3Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:21137"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="26">
        <location>
            <position position="1156"/>
        </location>
        <ligand>
            <name>[3Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:21137"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004802"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004909"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00004944"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00009716"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00011233"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00012079"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00022962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00023164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00023291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="ARBA" id="ARBA00024383"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="21">
        <source>
            <dbReference type="ARBA" id="ARBA00048151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="22">
        <source>
            <dbReference type="ARBA" id="ARBA00048867"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="23">
        <source>
            <dbReference type="ARBA" id="ARBA00057049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="24">
        <source>
            <dbReference type="ARBA" id="ARBA00068518"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="25">
        <source>
            <dbReference type="PIRSR" id="PIRSR000187-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="26">
        <source>
            <dbReference type="PIRSR" id="PIRSR000187-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="27">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="28">
        <source>
            <dbReference type="PROSITE" id="PS51278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="29">
        <source>
            <dbReference type="PROSITE" id="PS51379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="30">
        <source>
            <dbReference type="EMBL" id="OBZ91166.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="31">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="2061" mass="227322" checksum="CD610486AAD95375" modified="2016-11-30" version="1">MENTSWAGAIPAAQGLYNPEFEKDACGVGFMVHVKGVRSHKILSDASSILCNMTHRGASGADIRDGDGAGVMTGIPHQFFVNETSRELGITLPQEGHYAVGNLFMKGDTESVAECKKVFEQLAEALHLKVLGWRSVPRDSTIIGPAARSKEPAIEQPFVVLADQSKEFDEPYFERQLYVLRKHATHTLTMKKWFYICSLSNKNIIYKGQLTPKQVYSYFHDLNNVQYTTHFALVHSRFSTNTFPSWDRAQPMRWCAHNGEINTVRGNKNWMRSREGMMQSDKFGDELELLYPIIEEGGSDSAAFDNVLELLVINGVLSLPEAVMMMIPEAWQNNDNMSPEMKAFYKWAASLMEPWDGPALFTFSDGRYCGASLDRNGLRPCRYYLTNEDIMICASEVGTVFIDPETVVEKGRLKPGRMLLVDTVEGKIVDDKQLKLQTAAKRDFTQWIKNQSIVLKDIVERSNSVKPYTPALDDTTVQADPRLKXFGYTLEQLNLIMVPLASTGKEPLGSMGNDTALACLAEQPRLIYEYFRELFAQVTNPPIDPIREEIVMSLECYVGPEGNILEVDESQCQRLALPSPILSMEELSSIKNMSQFYPDWKVATIDITFPKADGVQGYVSTLERICNEVSQAIKDHYKVIVLSDRAVNAERVAISSLIAAGGVHHYLVRNKQRSRIALMVETAEAREVHHFCVLLGYGVDAVCPYLSLETMLKLHRERAVHEGLTPEKLIYNFKKGIDNGIHKVMSKMGISTLASYKGAQIFEALGIDDSVISRCFSGTASRIKGVTFDIFALDALTLHEAGYPTRNLVQPVGLPESGEYHWRDGGAPHIAEPTGIANLQDAVRQKNQSSYDAYSRNAYEAIKKCTLRGMLEFDFENSKAIPVEQVESWDKIVKRFVTGAMSYGSISMEAHSSLAIAMNKLGGKSNTGEGGEKPERSIPLENGDSMRSSIKQVASGRFGVTSFYLSDSEELQIKMAQGAKPGEGGELAGSKVSEEIASTRKTTPGIGLISPPPHHDIYSIEDLKQLIYDLKCANPRSRVSVKLVSEVGVGIVAAGVAKAKADHILISGHDGGTGASRWTGIKYAGLPWELGLAETHQTLVLNDLRGRVIVQTDGQIKTGRDIAIACLLGAEEWGFATTPLIALGCTMMRKCHLNTCPVGIATQDPELRKKFEGSPEHVVNFFYYLAEEMRSIMAKLGFRSINEMVGHAEKLKVNDALRTYKTANLDLSPILTPASTLRPGVSNVCATKQKHNLHIRLDNYLIDEAEAALSNKEKVRIEADVINTDRALGTTLSYHVSKRHGEAGLPADTIHVKLNGSAGQSLGAFLAPGIFFELEGDSNDYVGKGLSGGQIAIYPPKNSSFKSEENVIVGNVCLYGATSGKAFFRGIAAERFCVRNSGAYAVCEGVGDHGCEYMTGGRAVILGSTGRNFAAGMSGGIAYVLDLQGDFKQNVNMEMVELDTVNDPERVAELRDMIEDHRHYTGSEIADRVLKNFNEYLPKFVMVMPTEFRALLEKQRAEKLAAITPAKKECEKAHQKAEPQVEDLEDSVLSEEAILARRAKLDKVRGFKKYKRKTDPYRDAKKRGSXWDEVNVRLSRPELHEQAARCMDCGVPFCQSDTGCPIGNIIPKWNELVYKDNWKEALDRLMMTNNFPEFTGRVCPAPCENACVLGINEPPVAIKSIECAVIDRGFDEGWIVPNPPAQRTGKKIAVIGSGPAGLAAADQLNKAGHLVTVYDRNDRIGGLLMYGIPXMKLDKKIVQRRVDLLAAEGITFVTNAHVGVDVDVNTLREQNDAIVVATGATWPRDLKIPGREADGIHFAMEFLQANTKSLLDSELKDGQYLSAKGKKVVVIGGGDTGNDCIGTSIRHGCESVVNFELLPQPPASRAPDNPWPQFQRIFRVDYGHSEVKAHFGKDPREYCVLSKEFIVENGQVKGIKTVRVEWTKDDAGRWAMTEVPGSEETFEADLVLLSMGFLGPEEAVIKQLSIKQDGRSNIETPKGKYATSVPGVYAAGDCRRGQSLIVWGINEGRMCAREVDHNLMGSTYLPVTGGIQQRILPNHAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NS67</accession>
    <name>A0A1C7NS67_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_00132</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000003">
        <property type="protein sequence ID" value="OBZ91820.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NS67"/>
    <dbReference type="STRING" id="101091.A0A1C7NS67"/>
    <dbReference type="InParanoid" id="A0A1C7NS67"/>
    <dbReference type="OrthoDB" id="28939at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009563">
        <property type="entry name" value="SSSCA1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051888">
        <property type="entry name" value="UPF0148_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16537:SF1">
        <property type="entry name" value="PROTEIN ZNRD2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16537">
        <property type="entry name" value="SJOEGREN SYNDROME/SCLERODERMA AUTOANTIGEN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06677">
        <property type="entry name" value="Auto_anti-p27"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="60"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="176"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="195"/>
            <end position="211"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ91820.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="280" mass="31389" checksum="CC8CE2623CA99F85" modified="2016-11-30" version="1">MSSDPLRSKKEADQLLGSFLLQGWVMTDTICSQEGCCFPMMRSKDGSLSFCTHHDQLPNQGAHHNYKTTPSTPKELPQESKTVPVKAIPRASTDINSGDEELRIRRERREQSSKASQVIGQKMLQRWALLNEHCPNSSCYAVPLVRNPETHQMYCVICENIILTEQEVMELENKKKQDNKKQAKQSVEPIQKPSTTTTTTTTTATATATDTPNSKRQKVTSATTQASSNDVVTKLSKKMDELTQRVENCHDPKELCSLFKSIKQCANAIQACIEVNKAMR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NS80</accession>
    <name>A0A1C7NS80_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">WD repeat-containing protein 53</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">wdr53</name>
        <name evidence="4" type="ORF">A0J61_00036</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000001">
        <property type="protein sequence ID" value="OBZ91898.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NS80"/>
    <dbReference type="STRING" id="101091.A0A1C7NS80"/>
    <dbReference type="InParanoid" id="A0A1C7NS80"/>
    <dbReference type="OrthoDB" id="2161379at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45296">
        <property type="entry name" value="TRANSDUCIN/WD40 REPEAT-LIKE SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45296:SF1">
        <property type="entry name" value="TRANSDUCIN_WD40 REPEAT-LIKE SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="11"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="219"/>
            <end position="259"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OBZ91898.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="306" mass="33725" checksum="9FCD7944328C78CA" modified="2016-11-30" version="1">MMEVLEPLIELKGHKGSIISLEYSESSVIGDHLLASGSEDNTCRIWDLKSTRVAKGIKGFSEPVTSIKFAQKSSLPLIYIASGTKVHTFDLRNESVMLTEPIQTYEFSKDEINQIDVNENNKFMATADDEGVVNVIWSGGMDSKVYEWDFSRGLPTNIYDMSNKEPSAKQMFNPPFVYNMAVSSDGEWIAAGLGDTSIQLLSPPNKKQKKSELQEKRLEDGHNTLVNCLSFVSTTHLLSGSANGQVALWDLNTLEKRAFKTNDSFGRLNSLCVLESDNKDAMLQFAAAGTSQSNQSGALSIFTIKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NSI1</accession>
    <name>A0A1C7NSI1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Arrestin domain-containing protein C31A2.12</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_01511</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000049">
        <property type="protein sequence ID" value="OBZ90444.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NSI1"/>
    <dbReference type="FunCoup" id="A0A1C7NSI1">
        <property type="interactions" value="100"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NSI1"/>
    <dbReference type="InParanoid" id="A0A1C7NSI1"/>
    <dbReference type="OrthoDB" id="2333384at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030674">
        <property type="term" value="F:protein-macromolecule adaptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031625">
        <property type="term" value="F:ubiquitin protein ligase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070086">
        <property type="term" value="P:ubiquitin-dependent endocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.640">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014752">
        <property type="entry name" value="Arrestin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011021">
        <property type="entry name" value="Arrestin-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011022">
        <property type="entry name" value="Arrestin_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050357">
        <property type="entry name" value="Arrestin_domain-protein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11188">
        <property type="entry name" value="ARRESTIN DOMAIN CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11188:SF17">
        <property type="entry name" value="FI21816P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02752">
        <property type="entry name" value="Arrestin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00339">
        <property type="entry name" value="Arrestin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01017">
        <property type="entry name" value="Arrestin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="E set domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Arrestin C-terminal-like" evidence="2">
        <location>
            <begin position="178"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="391"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="405"/>
            <end position="420"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM01017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ90444.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="480" mass="53423" checksum="FC54E6401A51122E" modified="2016-11-30" version="1">MIQAFGKNIDLKINVVTDEIVLYGLAENAPAKVLRGSLFVTLSEPIKVKSVVLSFIGKMTVAWSEDSSLALGVGHHQQIHKQERNIIIHFWDFVKNKKKSLVVLEAGQHKWNFELPLPGNLPQSLESDAGSVSYRLKATIERPAFIQNIIKKKVIRIQRCVIPSQFELVQSLEIRSTLADKIVYDISAPSKIYAFGDKIPVTFKIEPLASTLKVHAIRASLKEYCSYRANERSKTDTRTICRVSLDNPFTPSSSTVVEKAGHTWKRVIELPVPPQSPMVFADTESDLIRIRHRLKFIISLVNAAGQVSELRSAVQVTMLESFAVTEELTCLPAYDEMWRSIPYSHDVLEQLRTQPSQAEAEPTLSDLTASRQPLTVSGWSRLLSLSSKTVPLSESHSDRTSNQEASSSNASTAVNSSANSIQDEDIERQQTLSDSQPWWDGVDLAKVPSYRTISSIDSTIVSNSLAPAYDSVLPRHATRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NSL8</accession>
    <name>A0A1C7NSL8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Putative magnesium transporter NIPA8</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">A0J61_00246</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000005">
        <property type="protein sequence ID" value="OBZ91676.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NSL8"/>
    <dbReference type="InParanoid" id="A0A1C7NSL8"/>
    <dbReference type="OrthoDB" id="2504919at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015095">
        <property type="term" value="F:magnesium ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037185">
        <property type="entry name" value="EmrE-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008521">
        <property type="entry name" value="Mg_trans_NIPA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12570">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12570:SF86">
        <property type="entry name" value="ADR321CP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05653">
        <property type="entry name" value="Mg_trans_NIPA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103481">
        <property type="entry name" value="Multidrug resistance efflux transporter EmrE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="6"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="46"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="68"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="101"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="140"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="220"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="254"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="281"/>
            <end position="305"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OBZ91676.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="369" mass="41367" checksum="2E06E439F6F648BB" modified="2016-11-30" version="1">MGTNDIWGPLVIALIASMTQACGISLQRKAHLIYQDANTSLYKQPLWISGFLIYTLSNLVGSTCTIGYLPIVILAPVGAIGLVFNAIFAKWILGDPFTKRTIFGTGLIVLGAGLIAGFGTVPEPNHTLDDLIKLYKRPSFIVYFSLVEAFILIGLLSTHVLEYWMELRPYDWISAIPDLKMYLGISYGVLGANISSQAMLFAKSGLELLILTLFQHDNQFIYPLTWAIVLALILTAILQLYYLNRGVQLCDTIILVPLNFCSFNVSCLFNGLVYYNQVNRLYWWQLLAVFFGIIILICGVLIISLQQQPAPIMLSDDVSSNYSDYSHPLFFKTSSLDEEAGMSWWTRMKFIYNKPVNEPDEHTGLLNSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NT28</accession>
    <name>A0A1C7NT28_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_00110</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000002">
        <property type="protein sequence ID" value="OBZ91856.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NT28"/>
    <dbReference type="InParanoid" id="A0A1C7NT28"/>
    <dbReference type="OrthoDB" id="2231920at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043900">
        <property type="entry name" value="DUF5788"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19101">
        <property type="entry name" value="DUF5788"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ91856.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="206" mass="24639" checksum="CAAA5C6A3A238133" modified="2016-11-30" version="1">MSDQLSIWHDNYLELRKKREDRIKLLQDHQKRVQRLEHHLFKIRNYLAKAVVERAQMQEKYEQLVQYDIWVTAEEHERIHLVRDKVEREYSEWVRRKKSRVCMIDEEAKKAKQHASHIIGIDRALVCLEELMRTHLLQEKEGQPELMKEIEAQTPPVFLRRFNSSYSFQSVNTANSKDSTSLSGALLKKWLEPRLQASQTHLQLAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NTX0</accession>
    <name>A0A1C7NTX0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Upstream stimulatory factor 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">USF1</name>
        <name evidence="3" type="ORF">A0J61_00999</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000027">
        <property type="protein sequence ID" value="OBZ90944.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NTX0"/>
    <dbReference type="STRING" id="101091.A0A1C7NTX0"/>
    <dbReference type="InParanoid" id="A0A1C7NTX0"/>
    <dbReference type="OrthoDB" id="690068at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00083">
        <property type="entry name" value="bHLH_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.280.10">
        <property type="entry name" value="Helix-loop-helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011598">
        <property type="entry name" value="bHLH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036638">
        <property type="entry name" value="HLH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46266">
        <property type="entry name" value="TRANSCRIPTION FACTOR TT8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46266:SF4">
        <property type="entry name" value="TRANSCRIPTION FACTOR TT8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00010">
        <property type="entry name" value="HLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00353">
        <property type="entry name" value="HLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47459">
        <property type="entry name" value="HLH, helix-loop-helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50888">
        <property type="entry name" value="BHLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BHLH" evidence="2">
        <location>
            <begin position="84"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="58"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="58"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="73"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="91"/>
            <end position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50888"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ90944.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="176" mass="20036" checksum="0F2AAB5CEEB632AC" modified="2016-11-30" version="1">MSTSPNKTPTDIPNDNNKTLDDKLPFEGLPPIQLPTPVIHYYIAPTMPPSPMEYRPSSWPNFPTSSPQPSSVRIHKATNRNNNKRKSSHSAVEKRRRERMNDKIEKLKTLIPSCTAQFPTSVQQPIHKLSVLQAAIDYIQELHDQLKNTLPQDDPVIKDISIVAMHQNKKQDKIKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NUH3</accession>
    <name>A0A1C7NUH3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Cutinase gene palindrome-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">CGPB</name>
        <name evidence="8" type="ORF">A0J61_00795</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000020">
        <property type="protein sequence ID" value="OBZ91144.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NUH3"/>
    <dbReference type="STRING" id="101091.A0A1C7NUH3"/>
    <dbReference type="InParanoid" id="A0A1C7NUH3"/>
    <dbReference type="OrthoDB" id="2162994at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00202">
        <property type="entry name" value="ZnF_GATA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.50.10">
        <property type="entry name" value="Erythroid Transcription Factor GATA-1, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.20">
        <property type="entry name" value="PAS domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051140">
        <property type="entry name" value="GATA_TF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013655">
        <property type="entry name" value="PAS_fold_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000679">
        <property type="entry name" value="Znf_GATA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013088">
        <property type="entry name" value="Znf_NHR/GATA"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00229">
        <property type="entry name" value="sensory_box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45658">
        <property type="entry name" value="GATA TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45658:SF18">
        <property type="entry name" value="PROTEIN GAT2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00320">
        <property type="entry name" value="GATA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08447">
        <property type="entry name" value="PAS_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00091">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00401">
        <property type="entry name" value="ZnF_GATA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57716">
        <property type="entry name" value="Glucocorticoid receptor-like (DNA-binding domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="PYP-like sensor domain (PAS domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00344">
        <property type="entry name" value="GATA_ZN_FINGER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50114">
        <property type="entry name" value="GATA_ZN_FINGER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50112">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="PAS" evidence="6">
        <location>
            <begin position="74"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="domain" description="GATA-type" evidence="7">
        <location>
            <begin position="348"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="12"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="237"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="309"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="17"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="32"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="250"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="277"/>
            <end position="288"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00094"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50114"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OBZ91144.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="389" mass="44587" checksum="7A274D2934CF721E" modified="2016-11-30" version="1">MQQPEYYSYILDNSKPLQTDDNNNIFNNLDLPTSQNLPQQPLLGESSSSSTNPQQQQQQQQLTSAKGTTDFRRRKNWSERILVEITGLLHVLSPTGKILYCSESTHELTGFRPHELVGQPLVDFLHVDDIDVFIRDFQMAFHMRSQIKTYYRFRRKDDSHVIFEVVGQPKSDHPGQAPQSFFGIAQPVPTRSGNLLDTFLELKTENNWLKKRIDELSAKYGPVNPQREEDSTMTNAPIALDPMSSHHRLSNTYPSSNNHSNTHHDSTHFSPPALPPSNSHHSNDSLNHMHTHIKSDPWLDSTDMDHHSFHTEDKHVSNPDQDMSADNLERKDKWKRRKKTKGSDEYVCADCGTTSSPEWRKGPQGPKTLCNACGLRWAKKNKKRDLNDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MU11</accession>
    <name>A0A1C7MU11_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">MULE transposase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_11628</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01002275">
        <property type="protein sequence ID" value="OBZ80323.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MU11"/>
    <dbReference type="STRING" id="101091.A0A1C7MU11"/>
    <dbReference type="InParanoid" id="A0A1C7MU11"/>
    <dbReference type="OrthoDB" id="2289420at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018289">
        <property type="entry name" value="MULE_transposase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47718">
        <property type="entry name" value="OS01G0519700 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47718:SF3">
        <property type="entry name" value="PROTEIN FAR1-RELATED SEQUENCE 5-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10551">
        <property type="entry name" value="MULE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MULE transposase" evidence="1">
        <location>
            <begin position="4"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="229"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF10551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ80323.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="229" mass="26070" checksum="09204D767EBFD7AE" modified="2016-11-30" version="1" fragment="single">MDQVFVIDATYKTNDRNMPLICVYGVHNLGADVLRTFPVAFAFVCDEQQVTYIWFMETLKNALGNTHLEQPVFVTDKCLALMEALETVFPESDKLLCIWHMMGNIKKELSKNGRFFDKKIKEEAIKLLAQFSCLSTQRAESGHRILKVGLSRRLDLISAFENIDAYCSLLKQKLALLEQKETQKQDLLMRRNNRLNRVRGKVSRAALIAAHSVCIAVESGEVARENGDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MUE4</accession>
    <name>A0A1C7MUE4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_11532</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01002157">
        <property type="protein sequence ID" value="OBZ80418.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MUE4"/>
    <dbReference type="STRING" id="101091.A0A1C7MUE4"/>
    <dbReference type="InParanoid" id="A0A1C7MUE4"/>
    <dbReference type="OrthoDB" id="2268133at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="212"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ80418.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="212" mass="24271" checksum="8128ED289ADFFD8B" modified="2016-11-30" version="1" fragment="single">MKNADLDKAYQSARNSESAALNSDKEHIFNICAHIINIYRHRRSSLNNSMKDNTELDGLVKLWAEVFESLFPDSQHNIKCRWGESKTHHNDYKVDCRVIAITNTQKVDVLDVEAARYLQNQKTNNDHLKLAIESKGVLDHIVRHAASFDPRKDMALMLQIGQNQCDVKVFSLCDRGLYCLWKEISLSLPPCPKLFAENADLWTATLELIRSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MW01</accession>
    <name>A0A1C7MW01_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">ARS-binding protein 1 N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_10930</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001521">
        <property type="protein sequence ID" value="OBZ81021.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="InParanoid" id="A0A1C7MW01"/>
    <dbReference type="OrthoDB" id="155630at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041188">
        <property type="entry name" value="HTH_ABP1_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18107">
        <property type="entry name" value="HTH_ABP1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ARS-binding protein 1 N-terminal" evidence="1">
        <location>
            <begin position="39"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF18107"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ81021.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="98" mass="11534" checksum="F5E83DF25536ED4B" modified="2016-11-30" version="1" fragment="single">MPYHLPNQANSNRIRPSDLTXNRARSLLPRMQQTQAGKKRMRLTDAEKLELGYRYFEVKPKISQESLCAWAKREFQLEEEPTQSTISRALQKYPSLKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MW71</accession>
    <name>A0A1C7MW71_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Chromo domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">A0J61_10860</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001453">
        <property type="protein sequence ID" value="OBZ81091.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MW71"/>
    <dbReference type="FunCoup" id="A0A1C7MW71">
        <property type="interactions" value="10"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7MW71"/>
    <dbReference type="InParanoid" id="A0A1C7MW71"/>
    <dbReference type="OrthoDB" id="433924at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="CDD" id="cd00024">
        <property type="entry name" value="CD_CSD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016197">
        <property type="entry name" value="Chromo-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000953">
        <property type="entry name" value="Chromo/chromo_shadow_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023780">
        <property type="entry name" value="Chromo_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051219">
        <property type="entry name" value="Heterochromatin_chromo-domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025768">
        <property type="entry name" value="TFG_box"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22812">
        <property type="entry name" value="CHROMOBOX PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00385">
        <property type="entry name" value="Chromo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00298">
        <property type="entry name" value="CHROMO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54160">
        <property type="entry name" value="Chromo domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50013">
        <property type="entry name" value="CHROMO_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51536">
        <property type="entry name" value="TFG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Chromo" evidence="5">
        <location>
            <begin position="105"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="domain" description="TFG box profile" evidence="6">
        <location>
            <begin position="384"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="38"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="162"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="366"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="TFG box" evidence="3">
        <location>
            <begin position="384"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="50"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="91"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="163"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="243"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="376"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="404"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00869"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50013"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51536"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OBZ81091.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="404" mass="46702" checksum="1D749F3435E0DC0E" modified="2016-11-30" version="1" fragment="single">MPSTKREKIDSKHHVIDLDADIGFDDDIASLDSDLKALGEKESSPVAEINKSRKEKSSSETTDKYPPRAMRQRTPKLESHPTRSASTQRKVKPEPVKKQEEEEEYEIERIEGHRIFKGKVVTYEIKWKGYPTSQNTTERANTIHADVYDLCAAYWDSLPHITRPSNAPKRTQPNPSPAVENESPNSLENKEAKAVSPKPQETSSPKKRSQANVSTNNKRPRLQEPKQEITPKALSPSPVTRQSSEESEKRTRKRNVESSEEEEEEVYARHVPDYMTELGYRFETEFPKANANWNRDIIKVCVQASPVNPKRILCYAEWNNGKKTIHPMNVAHQKIPQLNDYNSFNHNKAEHILYCIVSSCESKERIEQQQEQQQEQQHHHQGDNRRSRFHEERKLNMETFGQAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MWB3</accession>
    <name>A0A1C7MWB3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Tyr recombinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">A0J61_10893</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001491">
        <property type="protein sequence ID" value="OBZ81058.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MWB3"/>
    <dbReference type="STRING" id="101091.A0A1C7MWB3"/>
    <dbReference type="InParanoid" id="A0A1C7MWB3"/>
    <dbReference type="OrthoDB" id="2288922at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015074">
        <property type="term" value="P:DNA integration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.443.10">
        <property type="entry name" value="Intergrase catalytic core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011010">
        <property type="entry name" value="DNA_brk_join_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013762">
        <property type="entry name" value="Integrase-like_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010998">
        <property type="entry name" value="Integrase_recombinase_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35617:SF3">
        <property type="entry name" value="CORE-BINDING (CB) DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35617">
        <property type="entry name" value="PHAGE_INTEGRASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56349">
        <property type="entry name" value="DNA breaking-rejoining enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="25"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="62"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="250"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="308"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="25"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="62"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="324"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OBZ81058.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="728" mass="81099" checksum="70E7E3BF7DF95805" modified="2016-11-30" version="1" fragment="single">RFSSGQLLHDCSFAGKEVARFTTLHTTGNPKSHSVTPGNSQSNHEDTGSYVCSTTSSLVYPLPTTSEEPIGSQQGRLGYSSLPPQRVPQGVDMVARQPLLLEWQEHSPPDSGSDHLCGCKRHGLGLLCTSTEHSSSKDGVRLLDLTGSRHVNQLEGVEGGSSSPPNFPGPQKYDHFNPDRQHNLSGVYQQTRRHQVSIIDATSHSLLEVVSPEGHTVAGTPHTWSGESSCRLRISANILEKPMDVETISVRSNPTGVGSSRYRPLRRQDNPPPPKIRRMVAGSGVDLDRCLHDRLVHLREPIYTSTLEPDLEMPGENSLRPSAICNNSRPSLDASTLVPSAPPIECRSATTAPKRRRPSDNPFDCSSLSQQQLEAFRMEAIRSRFQSSAALGEGAKRLMMDTLLADTPTNRSYRSHHHHFLRWTHYHGIPINSYTPADMINFLADLQLYKNYQVATLLLARTAVTHLHHDPATIRNSAEVAVFLRSQKAQAPPVRLHKPTVDLTPTFALLRRSLPSTLSSCQRKLAFLLAFTCFLRPSDLNRIPFSSVAIDSVSGVLSFEVVAPKEKRAGRRIIKSYEVKPHQDRLLCPVETLRVLLPLRNRLHASCPLLFVHTKSPSSHIVDRTIEIWLRDYLSCSTSDSRISVRFLTSSLALKCGIPRDDIVTMGNWSNDSVFENHYRREHLTQFDFTNTLLPVAPATSFTLESDFLEEDDEFYDAVEHQKELVSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MX54</accession>
    <name>A0A1C7MX54_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_10562</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001236">
        <property type="protein sequence ID" value="OBZ81390.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MX54"/>
    <dbReference type="InParanoid" id="A0A1C7MX54"/>
    <dbReference type="OrthoDB" id="2287450at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ81390.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="121" mass="13555" checksum="839C724692CAB598" modified="2016-11-30" version="1">MSGSNRRKRQTDPNTQARKRDFSVYTCDNHLSQLVSLMECKPPRASPSDDFVKMANCLKDCLDKAIKNGVDHSALTVCGLLYESGCQRKGQRKHERKQFGETATCACHHLAPQSDSPKTRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MX66</accession>
    <name>A0A1C7MX66_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">26S proteasome non-ATPase regulatory subunit RPN1 C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_10932</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001523">
        <property type="protein sequence ID" value="OBZ81019.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MX66"/>
    <dbReference type="STRING" id="101091.A0A1C7MX66"/>
    <dbReference type="InParanoid" id="A0A1C7MX66"/>
    <dbReference type="OrthoDB" id="10252509at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008540">
        <property type="term" value="C:proteasome regulatory particle, base subcomplex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034515">
        <property type="term" value="C:proteasome storage granule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043161">
        <property type="term" value="P:proteasome-mediated ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041433">
        <property type="entry name" value="RPN1_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10943">
        <property type="entry name" value="26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10943:SF1">
        <property type="entry name" value="26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18051">
        <property type="entry name" value="RPN1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="26S proteasome non-ATPase regulatory subunit RPN1 C-terminal" evidence="2">
        <location>
            <begin position="8"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF18051"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ81019.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="67" mass="7319" checksum="FFD392E00F7BA110" modified="2016-11-30" version="1" fragment="single">VGQAVDVVGQAGRPKTITGFQTHSTPVLLAHSERAELATEEYLSLAPVLEGIVLLRKNPDYMEEDKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MY67</accession>
    <name>A0A1C7MY67_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Mitochondrial import inner membrane translocase subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">tim8_1</name>
        <name evidence="7" type="ORF">A0J61_10231</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Heterohexamer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Mitochondrion inner membrane</location>
            <topology evidence="5">Peripheral membrane protein</topology>
            <orientation evidence="5">Intermembrane side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="5">The twin CX3C motif contains 4 conserved Cys residues that form 2 disulfide bonds in the mitochondrial intermembrane space.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the small Tim family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001080">
        <property type="protein sequence ID" value="OBZ81721.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MY67"/>
    <dbReference type="FunCoup" id="A0A1C7MY67">
        <property type="interactions" value="166"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7MY67"/>
    <dbReference type="InParanoid" id="A0A1C7MY67"/>
    <dbReference type="OrthoDB" id="344165at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.810">
        <property type="entry name" value="Mitochondrial import inner membrane translocase subunit tim13 like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004217">
        <property type="entry name" value="Tim10-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035427">
        <property type="entry name" value="Tim10-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02953">
        <property type="entry name" value="zf-Tim10_DDP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144122">
        <property type="entry name" value="Tim10-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0143">Chaperone</keyword>
    <keyword evidence="5" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="2 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="2 5" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="3 5" id="KW-0653">Protein transport</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0811">Translocation</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Tim10-like" evidence="6">
        <location>
            <begin position="16"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006720"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU367043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF02953"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OBZ81721.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="84" mass="9687" checksum="225EB3823998EC2E" modified="2016-11-30" version="1">MSQPQFSENDQRELAEFLQAEQAKARVQETVHSMTDTCWDKCISKVNNKLDRSEEACLANCVDRFLDTSLFIVKRLEDLRSSGM</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MZ09</accession>
    <name>A0A1C7MZ09_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_09905</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000968">
        <property type="protein sequence ID" value="OBZ82047.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MZ09"/>
    <dbReference type="STRING" id="101091.A0A1C7MZ09"/>
    <dbReference type="InParanoid" id="A0A1C7MZ09"/>
    <dbReference type="OrthoDB" id="2285856at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ82047.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="89" mass="10602" checksum="07FEA488BBDFBE2E" modified="2016-11-30" version="1">MHKEDPSVTSVAVHLENEQPVCFDPEANAKEIQQILINTNSTLMTLFKYHATNQDKHDHLYQKFTFCYTWKRDERKRQARKKGFVDPTY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-06-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MZ80</accession>
    <name>A0A1C7MZ80_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_09745</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000927">
        <property type="protein sequence ID" value="OBZ82205.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MZ80"/>
    <dbReference type="InParanoid" id="A0A1C7MZ80"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ82205.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="79" mass="9284" checksum="A08A7EE604E658EA" modified="2016-11-30" version="1">MSRCCDSGASFNARELVIAEKFPLKIQVGFRAIDSVELERFQKILRELQVLRHDRVELQYLISKFRTQWNLNILVKCAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-06-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MZ92</accession>
    <name>A0A1C7MZ92_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_10224</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001079">
        <property type="protein sequence ID" value="OBZ81726.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MZ92"/>
    <dbReference type="InParanoid" id="A0A1C7MZ92"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ81726.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="25" mass="2884" checksum="1F6B06908FC72B24" modified="2016-11-30" version="1" fragment="single">CDPTFFDALYENYQTTITSATKPEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MZK3</accession>
    <name>A0A1C7MZK3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Putative mitochondrial ATP-dependent helicase irc3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">irc3</name>
        <name evidence="4" type="ORF">A0J61_09624</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000893">
        <property type="protein sequence ID" value="OBZ82325.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MZK3"/>
    <dbReference type="FunCoup" id="A0A1C7MZK3">
        <property type="interactions" value="13"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7MZK3"/>
    <dbReference type="InParanoid" id="A0A1C7MZK3"/>
    <dbReference type="OrthoDB" id="16911at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036121">
        <property type="term" value="F:double-stranded DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061749">
        <property type="term" value="F:forked DNA-dependent helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000403">
        <property type="term" value="F:Y-form DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032042">
        <property type="term" value="P:mitochondrial DNA metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070125">
        <property type="term" value="P:mitochondrial translational elongation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd18799">
        <property type="entry name" value="SF2_C_EcoAI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006935">
        <property type="entry name" value="Helicase/UvrB_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050742">
        <property type="entry name" value="Helicase_Restrict-Modif_Enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47396:SF1">
        <property type="entry name" value="ATP-DEPENDENT HELICASE IRC3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47396">
        <property type="entry name" value="TYPE I RESTRICTION ENZYME ECOKI R PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04851">
        <property type="entry name" value="ResIII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 4" id="KW-0347">Helicase</keyword>
    <keyword evidence="1 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="2">
        <location>
            <begin position="42"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="3">
        <location>
            <begin position="256"/>
            <end position="419"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OBZ82325.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="630" mass="71503" checksum="6BDA542E005FACEE" modified="2016-11-30" version="1">MFRVLFVKKNVSFTLSQRLYSTAITFNMLRPYQKDCIKTTLTELENGCHRQIVSLPVGSGKTVIMSNLIPLIPSPTPKATKVLLLAHRTELLDQAHNQITKYNPSLNVQIEQGKRTVDLDKADVIIASVPTLGRKGSPRIEKFDPHEFKAILIDEAHHAVAETYTNILDYFGILDDANKKLLWGCSATVKRHDGKALNAVFDKIAYHVGFLEMIEQGFLSSMRVTTVKTDIDLDQVRYTKVDFVEKELAPVINTDTRNEVIVSSWKKYAHEQDRKSTLVFALNIEHTIELCNKFLDAGVNAKCITSKTNAIERLQILEEFKSGKIPVLVNCAILTEGTDIPCVDCILMTRPTRSATLFQQMFGRGLRLYPGKENCLVVDFVDNFTRSGPDGLITVPTLLGLDSSSVTENADVLELEELAERKKKEETEDAREIDPELVSIKVTEYNDLKELMVDISTTNEIRSTSSFNWINVGNDKCVLNIFNTGYIVLERTNGRWKATFRREDVKKNFFPRPLEIPLETEDLPSAIRASETWIQSNLKVNRSFMLRSAPFRKHKITTPQQDALSRYKIEVSPNLTKGQAMDLLTKLKYGQLSVWKKEIKLSDKMQAAEQKKMDAAILRRENQAKFTVLH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MZX5</accession>
    <name>A0A1C7MZX5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_09660</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000904">
        <property type="protein sequence ID" value="OBZ82288.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MZX5"/>
    <dbReference type="InParanoid" id="A0A1C7MZX5"/>
    <dbReference type="OrthoDB" id="2276242at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ82288.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="135" mass="15827" checksum="306E2463C9220608" modified="2016-11-30" version="1">MVTDQLYKASETFPKIPSNIDRRSLNTIIKEYSIRNKLVVSVTRFDAKSLIFQCVKSGKQREAKRIENPSKCRTKMSQKTERPYTIKFFKPRGKNLLNHLDPKNEMSIEQLKDSCNSLYLAFLRCIDHSFIDNHI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N089</accession>
    <name>A0A1C7N089_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative germ cell-less protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">GMCL1P1</name>
        <name evidence="3" type="ORF">A0J61_09441</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000851">
        <property type="protein sequence ID" value="OBZ82507.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N089"/>
    <dbReference type="STRING" id="101091.A0A1C7N089"/>
    <dbReference type="InParanoid" id="A0A1C7N089"/>
    <dbReference type="OrthoDB" id="6359943at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000210">
        <property type="entry name" value="BTB/POZ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47369">
        <property type="entry name" value="BTB/POZ DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47369:SF1">
        <property type="entry name" value="BTB_POZ DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00651">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00225">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54695">
        <property type="entry name" value="POZ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50097">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BTB" evidence="2">
        <location>
            <begin position="92"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="364"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="586"/>
            <end position="615"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="19"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="364"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="590"/>
            <end position="603"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ82507.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="675" mass="77258" checksum="ED56AE23C47EC940" modified="2016-11-30" version="1">MEEYSQQRTNSVQATPQENRNKSTKVTDHPFLPSSVAQSEFHTTFAESKSTSYTAAYSTASANNSSKYDWRIHSLALCRHILNRGLLDGIGSDIQIYIPSWKKTYHLHKLILDQNPYFKLLLQGPFLESEKSQIDLYLENEDNPFIDMESFQFVLDYLYGKIEQPSIYQSNVKQILATCSYFQIDAICNLCVDFILKSLNQANAIDYLLFSNEYMVIGNDRICDAVCAFLCREAYGMSRSILVALPLEWLEKIIESDAFWVPSEFERYKFIKQVITARYAFYLTRKDSFVMSELDTNPECHIICKSIYYMHMTFEQLESIRNDKNPFTKKSLVPEKVLKDALWLQVQLRSRIESIQEKDTKLGMAVSRDEREKEQDNKDDNNDEAYKYHYPIPTDDTTTYTGESAISLASMSIHQTKRRISEKSEQYSVYPPFRFSVEFTDVASLKHGMRVYSDTVFYAGSNWNMYIQKTRSQRKGILQLGVYLHRQSVPQGYNSCQNTASSNSTPTAILASNSDPLNSRCTESSSSDTFSFSKYIDKRKVVKTWFKIYCPTRGPKHALTLFQSSPDNFSVLQSWGWRSTTLCADEEAHGSQSTDASNNSLADSNEEPNSSSTSNDLFATTVVHASNTPNQLQYLQSMYDLRTLNSTSNTNCQQGHKHNVPAGPTLRFTVVMGHV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N0Z1</accession>
    <name>A0A1C7N0Z1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Armadillo repeat-containing protein 8</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">Armc8</name>
        <name evidence="6" type="ORF">A0J61_09615</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000891">
        <property type="protein sequence ID" value="OBZ82336.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N0Z1"/>
    <dbReference type="STRING" id="101091.A0A1C7N0Z1"/>
    <dbReference type="InParanoid" id="A0A1C7N0Z1"/>
    <dbReference type="OrthoDB" id="5559898at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034657">
        <property type="term" value="C:GID complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043161">
        <property type="term" value="P:proteasome-mediated ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000225">
        <property type="entry name" value="Armadillo"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038739">
        <property type="entry name" value="ARMC8/Vid28"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15651">
        <property type="entry name" value="ARMADILLO REPEAT-CONTAINING PROTEIN 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15651:SF7">
        <property type="entry name" value="ARMADILLO REPEAT-CONTAINING PROTEIN 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00514">
        <property type="entry name" value="Arm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00185">
        <property type="entry name" value="ARM"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OBZ82336.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="270" mass="30138" checksum="035DB327038D19D3" modified="2016-11-30" version="1">MTTSKYEESIKELSSNDDLKRLKALKFIKNSVIGNKTKKELYIKLGVVQRLVEYLSLPDNDASTDLKIQAVTILGSIAYGKDENVSTVVASGAIVPLLDTLELPRDKTPLESILERRKLIEATTRALKAIFASSRSIRYDSFSGKHIHDLILLLDTTSSYLTRKPQQTNVSSEALSFAMIAEFTASIVAKCCDTQIQQLQLEEAGAIQPLVNLLHSGCIKAQKASLDAIATLCRENKELGEQIIRTKCKKEKRQKEIYVRMISFILHPIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N1E9</accession>
    <name>A0A1C7N1E9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_09057</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000763">
        <property type="protein sequence ID" value="OBZ82897.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N1E9"/>
    <dbReference type="STRING" id="101091.A0A1C7N1E9"/>
    <dbReference type="InParanoid" id="A0A1C7N1E9"/>
    <dbReference type="OrthoDB" id="6499973at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="61"/>
            <end position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ82897.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="109" mass="11971" checksum="B96ECA4763375CDB" modified="2016-11-30" version="1">MVITPLWFNRRRGLATGIASGGTGIGGPEHRLDLPFSSCFDCDAIACLLIKEAIFIFRNMSFFFILWTGGSIITTMGYFIPYLPAYLDLSASQSSVLIAFSFIGRMMVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N1M4</accession>
    <name>A0A1C7N1M4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Acyl-CoA-binding domain-containing protein 5A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">acbd5a</name>
        <name evidence="4" type="ORF">A0J61_09429</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000848">
        <property type="protein sequence ID" value="OBZ82519.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N1M4"/>
    <dbReference type="STRING" id="101091.A0A1C7N1M4"/>
    <dbReference type="InParanoid" id="A0A1C7N1M4"/>
    <dbReference type="OrthoDB" id="346910at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000062">
        <property type="term" value="F:fatty-acyl-CoA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006631">
        <property type="term" value="P:fatty acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.80.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022408">
        <property type="entry name" value="Acyl-CoA-binding_prot_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000582">
        <property type="entry name" value="Acyl-CoA-binding_protein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035984">
        <property type="entry name" value="Acyl-CoA-binding_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014352">
        <property type="entry name" value="FERM/acyl-CoA-bd_prot_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23310">
        <property type="entry name" value="ACYL-COA-BINDING PROTEIN, ACBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23310:SF133">
        <property type="entry name" value="COA BINDING PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G12300)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00887">
        <property type="entry name" value="ACBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00689">
        <property type="entry name" value="ACOABINDINGP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47027">
        <property type="entry name" value="Acyl-CoA binding protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00880">
        <property type="entry name" value="ACB_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51228">
        <property type="entry name" value="ACB_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0446">Lipid-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ACB" evidence="3">
        <location>
            <begin position="7"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="235"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="259"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="239"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="262"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="280"/>
            <end position="307"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51228"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OBZ82519.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="408" mass="47050" checksum="BF1537EA6EEDBBB9" modified="2016-11-30" version="1">MNSSYTTQLCFAHALSIVRAIPPDTTLQPTAADKLRFYGLYKQATEGDTNIPRPSSRQIVDYAKWKAWHRMKGMSPVEAQRLYVDSLIQLLAELIYRYPHHPHLEFIKNALSELQFDEQRHLDDTQVDEEAESFQDAYDPAEFESQEHFLSRFEADQLMEENAILSPPATSTQFSFKPPHRYSVSDANVADYPITPIASPHTGQWVQGQLEQQQPHRLPIEPDLISEADTLDREVAKVTQSLTQSSPTQSPYIPVHYDARKSSQPSFSQKPSSTRKKNRTVSASTAHTTRSASLSSSSSLNSSKQTSNRAIERLQTELTALTEQMDQLRQNIKTREERDRQFRWSPWYIFKLLLKHLLVNSAIFMIAFYVLWKRNSPLADKVIAYLRPWIRNIVRNILRNIVFWKVTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N2P1</accession>
    <name>A0A1C7N2P1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">ER membrane protein SH3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_08636</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000684">
        <property type="protein sequence ID" value="OBZ83317.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N2P1"/>
    <dbReference type="InParanoid" id="A0A1C7N2P1"/>
    <dbReference type="OrthoDB" id="5229808at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006888">
        <property type="term" value="P:endoplasmic reticulum to Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013248">
        <property type="entry name" value="Psh3/Shr3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28228">
        <property type="entry name" value="SECRETORY COMPONENT PROTEIN SHR3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28228:SF1">
        <property type="entry name" value="SECRETORY COMPONENT PROTEIN SHR3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08229">
        <property type="entry name" value="SHR3_chaperone"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00786">
        <property type="entry name" value="SHR3_chaperone"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="63"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="91"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="137"/>
            <end position="159"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ83317.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="178" mass="19378" checksum="56532A8EA7CF1AC2" modified="2016-11-30" version="1">MPGEHMQSAKVVLILCSCFFAYGTTWSDWAFDYYFLWANIAEHPGAVARATQYYISRASAPDIIKYIPFINLMIAAVGFAAGLANMTDGNVLFDGASLVLMLFAISTYSTSVKPAIENIAQTEDVAELSQNLKNIAAAHFIMTLAITGIVGLQITHYALTKRADSAEKVEAAVEKKNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N3R6</accession>
    <name>A0A1C7N3R6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">protein-tyrosine-phosphatase</fullName>
            <ecNumber evidence="2">3.1.3.48</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">Mkp3</name>
        <name evidence="8" type="ORF">A0J61_08652</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.48" evidence="2"/>
    <dbReference type="EMBL" id="LUGH01000688">
        <property type="protein sequence ID" value="OBZ83296.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N3R6"/>
    <dbReference type="STRING" id="101091.A0A1C7N3R6"/>
    <dbReference type="InParanoid" id="A0A1C7N3R6"/>
    <dbReference type="OrthoDB" id="273181at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004725">
        <property type="term" value="F:protein tyrosine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043409">
        <property type="term" value="P:negative regulation of MAPK cascade"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd14498">
        <property type="entry name" value="DSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.190.10">
        <property type="entry name" value="Protein tyrosine phosphatase superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.250.10">
        <property type="entry name" value="Rhodanese-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000340">
        <property type="entry name" value="Dual-sp_phosphatase_cat-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029021">
        <property type="entry name" value="Prot-tyrosine_phosphatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001763">
        <property type="entry name" value="Rhodanese-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036873">
        <property type="entry name" value="Rhodanese-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000387">
        <property type="entry name" value="Tyr_Pase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020422">
        <property type="entry name" value="TYR_PHOSPHATASE_DUAL_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10159">
        <property type="entry name" value="DUAL SPECIFICITY PROTEIN PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10159:SF530">
        <property type="entry name" value="DUAL SPECIFICITY PROTEIN PHOSPHATASE DDB_G0271350-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00782">
        <property type="entry name" value="DSPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00581">
        <property type="entry name" value="Rhodanese"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00195">
        <property type="entry name" value="DSPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00450">
        <property type="entry name" value="RHOD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52799">
        <property type="entry name" value="(Phosphotyrosine protein) phosphatases II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52821">
        <property type="entry name" value="Rhodanese/Cell cycle control phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50206">
        <property type="entry name" value="RHODANESE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50056">
        <property type="entry name" value="TYR_PHOSPHATASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50054">
        <property type="entry name" value="TYR_PHOSPHATASE_DUAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0904">Protein phosphatase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rhodanese" evidence="7">
        <location>
            <begin position="14"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="domain" description="Tyrosine-protein phosphatase" evidence="5">
        <location>
            <begin position="261"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="domain" description="Tyrosine specific protein phosphatases" evidence="6">
        <location>
            <begin position="328"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008601"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013064"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OBZ83296.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="441" mass="50865" checksum="3B55635826B50CB8" modified="2016-11-30" version="1" fragment="single">WPPLEPEALARLIELDEVILIDVRNLIDYQRRRIRQSLNVNLPSLLIKRYQRGTIANFNLENFITTSEGRAIYQAQCKKGPDVPRTGTLLEQKAAEAELRHRRKKCWVVYDEEMQQDDQTSQAWTLLHVLDRFVQADRSHEGQVYYLQGGFQGFQARFEHLLETTSATFSLPDPPQMKLGNLPRRSISYTIGESKNKRTSLFTLDTQAARVNNANALARRAKRRQPEDTQMAMPATQLIRVTEDEETMTASPRTEQDFSFVISEIIPGFLFVGPEIETEEQAKALDERHIKRVLNMAEECHDEGLASRSIVYHKISARDTLEMKNIELVMMEAVCFIEEAKKHHEPIYVHCKAGKSRSITAILAYLVTSERWTLKRAYRHVIKARPNMSPNIGFISELMKMEGKVHGRVSSFMETDWQSTSLPSPEYANELFQLEKAWQIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N4M0</accession>
    <name>A0A1C7N4M0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">UDP-galactose:fucoside alpha-3-galactosyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">agtA_0</name>
        <name evidence="4" type="ORF">A0J61_08335</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the glycosyltransferase 77 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000631">
        <property type="protein sequence ID" value="OBZ83616.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N4M0"/>
    <dbReference type="STRING" id="101091.A0A1C7N4M0"/>
    <dbReference type="InParanoid" id="A0A1C7N4M0"/>
    <dbReference type="OrthoDB" id="540503at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005069">
        <property type="entry name" value="Nucl-diP-sugar_transferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052636">
        <property type="entry name" value="UDP-D-xylose:L-fucose_XylT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47032">
        <property type="entry name" value="UDP-D-XYLOSE:L-FUCOSE ALPHA-1,3-D-XYLOSYLTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47032:SF1">
        <property type="entry name" value="UDP-D-XYLOSE:L-FUCOSE ALPHA-1,3-D-XYLOSYLTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03407">
        <property type="entry name" value="Nucleotid_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="7"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="domain" description="Nucleotide-diphospho-sugar transferase" evidence="3">
        <location>
            <begin position="140"/>
            <end position="347"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF03407"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OBZ83616.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="372" mass="43284" checksum="5A5F8BB3E9CD5B72" modified="2016-11-30" version="1">MLDQRKSLYLIVIILLVSSLVYLSHLYSRETQPKTDASYLTNEQTFFDANTTYDPFVCDCSTIAQNISSSLPSEPITLPDENQNTQDIEIPDHLPPPPAALMKKIKANLLENRVLVVATANFGMRHHVYNWIESLKRTGQKKFLIFCFDQKLYDHLKAAGYSRHASMIPDIWFHTQVEADFKTYFSKEYRIITHSKTLVVQQLLYLDINVFFSDVDIIWLRPNIVDYVNTLMQMRQETHVLFQQEGMNQQEVNSGFYLMRPSLEMKRLLAETIAIQDANDAKTQQGAMNMALDKLNLDLRTGSVVLLDALHFPNGFVYFTQDLPNKHGIKPFIIHANYLVGEEKKTKLKEYDYWYLNETWLDQIDTQLELQH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N4M9</accession>
    <name>A0A1C7N4M9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_07937</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000569">
        <property type="protein sequence ID" value="OBZ84011.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N4M9"/>
    <dbReference type="InParanoid" id="A0A1C7N4M9"/>
    <dbReference type="OrthoDB" id="2156793at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ84011.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="270" mass="31188" checksum="E855E7E7CB705281" modified="2016-11-30" version="1">MSQHPHSAIQIFQFLSSLHDHCPTQETFESVLLSLRTPRFAPVSSITDRWAPVLATETPNLVQNFQSMMASAAKSPDYDSLLIRVAEHHPLIYRVSCFLEDDLQLELFVRCLCLDSTTPVSAVEVQATLKQFLDQLPQDSREYVQAILKEDPHGYYAESFDGFLDLDKVYKIVNDSQLFNQLMAIIQTNTQNQVIWSQTIQEVYELVYNKGIWNQLAPLLQQVYIRSDNTQYTSYEDYVQKNFLDDGGQQYLDEEIDRAQVEHMFGNLTM</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N4P9</accession>
    <name>A0A1C7N4P9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_08314</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000628">
        <property type="protein sequence ID" value="OBZ83636.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N4P9"/>
    <dbReference type="InParanoid" id="A0A1C7N4P9"/>
    <dbReference type="OrthoDB" id="2218844at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ83636.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="100" mass="12017" checksum="7E2DD66AC929815F" modified="2016-11-30" version="1">MSNNNKPVHLETTPRVYYENYTKTMPSYDLYPALSRRLGNGYVHQPVRPKTLSKKQNHFLCTSPRRIQHREQQQNTQPPWDLYPAMMRSYRNLDNNDQHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N4Y9</accession>
    <name>A0A1C7N4Y9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_07829</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000553">
        <property type="protein sequence ID" value="OBZ84121.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N4Y9"/>
    <dbReference type="InParanoid" id="A0A1C7N4Y9"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008889489" evidence="2">
        <location>
            <begin position="25"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="59"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="70"/>
            <end position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ84121.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="148" mass="15367" checksum="EBA31111DFF7813B" modified="2016-11-30" version="1">MHFSRLISLVAAFLAIALIQENYALRLDRSKLNQFLKRADTTTSSPSLPQRQFDCSVAQNSSNPACFTPTPTPTPTPSPSPSPAPIAGVPPVPAVPPLPSLPALSPVPPVDLTKTMPNLPDTSGLGAFSLPDTSSITPGLLSGGAKED</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N503</accession>
    <name>A0A1C7N503_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_09533</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000872">
        <property type="protein sequence ID" value="OBZ82414.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N503"/>
    <dbReference type="InParanoid" id="A0A1C7N503"/>
    <dbReference type="OrthoDB" id="10666105at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ82414.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="168" mass="16769" checksum="A50FE32C591F550B" modified="2016-11-30" version="1" fragment="single">SALTGLTSALSSLPGGFTGILGSLGSSADVSNVLNLLTGNVQLPSLPNLSLPSLTFPNPLLSSLGLNANLAGNIGSNLSGLFSGALSGGLPQLPSLSPSITSDLLGQAIKVLQAAQAFSGQGIDPTINSVLNVANQAQLQSNEVVKQLALALTLKAIQNIGYNIAVNI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N565</accession>
    <name>A0A1C7N565_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Exocyst complex component Sec8</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">sec8</name>
        <name evidence="8" type="ORF">A0J61_08162</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the SEC8 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000604">
        <property type="protein sequence ID" value="OBZ83789.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N565"/>
    <dbReference type="FunCoup" id="A0A1C7N565">
        <property type="interactions" value="39"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N565"/>
    <dbReference type="InParanoid" id="A0A1C7N565"/>
    <dbReference type="OrthoDB" id="272977at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000145">
        <property type="term" value="C:exocyst"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006893">
        <property type="term" value="P:Golgi to plasma membrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006612">
        <property type="term" value="P:protein targeting to membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006904">
        <property type="term" value="P:vesicle docking involved in exocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090522">
        <property type="term" value="P:vesicle tethering involved in exocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039682">
        <property type="entry name" value="Sec8/EXOC4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007191">
        <property type="entry name" value="Sec8_exocyst_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048630">
        <property type="entry name" value="Sec8_M"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14146">
        <property type="entry name" value="EXOCYST COMPLEX COMPONENT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14146:SF0">
        <property type="entry name" value="EXOCYST COMPLEX COMPONENT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20652">
        <property type="entry name" value="Sec8_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04048">
        <property type="entry name" value="Sec8_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4" id="KW-0268">Exocytosis</keyword>
    <keyword evidence="3 4" id="KW-0653">Protein transport</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Exocyst complex component Sec8 N-terminal" evidence="6">
        <location>
            <begin position="49"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="domain" description="Exocyst complex component Sec8 middle helical bundle" evidence="7">
        <location>
            <begin position="310"/>
            <end position="570"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="800"/>
            <end position="836"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="808"/>
            <end position="828"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU367079"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF04048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF20652"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OBZ83789.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="1066" mass="123740" checksum="09FAF8F890368A72" modified="2016-11-30" version="1">MSGNPFLQSDASSIPNSPRNRMHMMPSSSPVRSDDYYDDDMTRGNFSEFEAVLREIHEGWAFMLEDNFDPVTLTLKLMDDSSVGKKKDYKAFQRVLYNLDMALKTIVNDYYKGFNSSIGTFGGVLQYINDSSSRVVQMKSNLKKCKEELLSKRSDLLNLWDKSQQYKEMLSILETIEELRTTPEKIENMMDSKLVLGASKLLVSSTKQAMNKDMIKIGALDDVRRSLLSQKNALYDLIIEELHDHLYLKNAHCDNRWSAYVPQQQDLPEIPIKPREFNESSQKEQFKDYQDPENMFALEHDVLAEDPEKNPETDSYYYIEIMTEALLVLDEIPTAIETIQERLPFEVHSIVDRTIAEVELRHMNLKSFQRRNKSNDENDIYCLDKANSESKNEILKDLLWTLYSKLEAVLCGHRFLETCLRRIQKRNELAKANLEEVETGRDFRVYHFHEIWRPVQTEIRSILQDYLTSSDQNIVSVNEDKPYRGKRDNPRQMFTFADAAGDENLDESYENLRKTLLMSYKKQVPGFSGSNASIHSIIVDKYGNDISSKSYKVLVKPDAYNVSVLLKPTMAFLNRLRQVFPSYDDRNEEGFGSFLDDFAVNVFLPQIEEKVMQLIQHATVGLDAFQDARDYIDYSRYPIAKSAVALISVIQSLCRTMHSMPFHTDEYVRLVEVVLLKFYEKCYQRFYSTVARGSSYADNQQKNAAEVTISTSGDWAQDESLVGLLAQNPFFNEDSTMDQEYMKALNQTEITMELKLKNDRLLEPNELIFDSKKLIALGRLYHTLKWFVREIWDLRSSNVSPSLTNSSMKEDTDSYEVRKSKRWSRQELKPQTLENSDDKRPVLLPLHSEIAKRFDALLTTYQQLAETCLFTLRLEGRCHTMYYLEMAIRDGNYHLEDESFEPDPYIITLNSDLMELDDCINASLPHKDELFAFEGLPALIVHILVSEAVYIKKLNKNGVQKMNRNILALQQNLSNFVPISQCSVMERAREYYQLYMLGSEGIIRSIQENGAKFTFDEYRVMLGLIHDVAREQDEENTTTEEKKTSNSAKYSEWLMELVEVMADYEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N5D1</accession>
    <name>A0A1C7N5D1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Putative 4-coumarate--CoA ligase 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">4cl1_0</name>
        <name evidence="5" type="ORF">A0J61_07719</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ATP-dependent AMP-binding enzyme family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000538">
        <property type="protein sequence ID" value="OBZ84231.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N5D1"/>
    <dbReference type="STRING" id="101091.A0A1C7N5D1"/>
    <dbReference type="InParanoid" id="A0A1C7N5D1"/>
    <dbReference type="OrthoDB" id="1898221at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016405">
        <property type="term" value="F:CoA-ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05911">
        <property type="entry name" value="Firefly_Luc_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.300.30:FF:000007">
        <property type="entry name" value="4-coumarate--CoA ligase 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="entry name" value="N-terminal domain of ligase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025110">
        <property type="entry name" value="AMP-bd_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_synth/lig_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24096:SF149">
        <property type="entry name" value="AMP-BINDING DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24096">
        <property type="entry name" value="LONG-CHAIN-FATTY-ACID--COA LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13193">
        <property type="entry name" value="AMP-binding_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56801">
        <property type="entry name" value="Acetyl-CoA synthetase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0436">Ligase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AMP-dependent synthetase/ligase" evidence="3">
        <location>
            <begin position="31"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="domain" description="AMP-binding enzyme C-terminal" evidence="4">
        <location>
            <begin position="445"/>
            <end position="525"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF13193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OBZ84231.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="548" mass="60772" checksum="27B16CE23FEE85EC" modified="2016-11-30" version="1">MPIYKSTRDPIEIPNIDIYSFLFNPNRFNTTRSPDRPLLIDGVTGESISFGQAKEWIDSIAHGWKHHIGLEKGNVVAVFAPNQYDHAILYFSLLAAECTVSPGNPNYTEAEFEHQIRTSEAKAIVTIPELLPVLARIAERHAIPQERIFLFGHQTIGKARPFRSIASQHHAPICTDQINPKQDLAFICFSSGTTGVAKGVMLTHHNFVSQAVTVFDFEGTDSNRENDIIIGFLPFFHIFGLTTLVLRAFYSNTPVVVLPKYHLETVCQLIERYRITIAPVVPPVVVQLAKNEVVTKYDLSSLRMMTSGAAPLGIEHIEALHRRVKAPIRQGYGLTETTAGCMYQKIGMSPAGASGVLVANMECKLVDQDGNDVGPGQAGEILFKGPMVMKGYLNDDKANAETFTPDGWMKTGDIAKYDAKTGEFYIIDRIKELIKYKGYQVAPAELEALLMSHASVADCCVVGVYDNTQATELPRAYVVLQSSMPPTKATVDAINAFVESHVVNHKRLRGGIRLVSWIPKSASGKILRRQVREWIEKEQAQEPLVARL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N5Y8</accession>
    <name>A0A1C7N5Y8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">A0J61_07528</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Chromosome</location>
            <location evidence="2">Centromere</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the CENP-N/CHL4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000512">
        <property type="protein sequence ID" value="OBZ84421.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N5Y8"/>
    <dbReference type="STRING" id="101091.A0A1C7N5Y8"/>
    <dbReference type="InParanoid" id="A0A1C7N5Y8"/>
    <dbReference type="OrthoDB" id="6585699at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000775">
        <property type="term" value="C:chromosome, centromeric region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005654">
        <property type="term" value="C:nucleoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034080">
        <property type="term" value="P:CENP-A containing chromatin assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007059">
        <property type="term" value="P:chromosome segregation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052011">
        <property type="entry name" value="CENP-NAC/CAD_complex"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007902">
        <property type="entry name" value="Chl4/mis15/CENP-N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46790">
        <property type="entry name" value="CENTROMERE PROTEIN N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46790:SF1">
        <property type="entry name" value="CENTROMERE PROTEIN N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05238">
        <property type="entry name" value="CENP-N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0137">Centromere</keyword>
    <keyword evidence="4" id="KW-0158">Chromosome</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="372"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="383"/>
            <end position="403"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004584"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005566"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OBZ84421.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="414" mass="48211" checksum="E268B704E330C0F9" modified="2016-11-30" version="1">MLTEKDLVLIKHDDKIERILYGLRHKQLLMIIKPWFDIPELRPENESTTLDHYFDPNLMKANIIKRMLTKDWARGFRAIQLAHIDLYKLILNADSKRWNIVRLLKKSGDLRLDLEVTAVQELLMGYLTQFYSCYLAHIKDSHTGMYWIRIQLDQAQDFSIRAKRTFKGCIVYVPRSEFLLITGNIKSNINPDIKEALLRVFKAEDLVYQSVQDRAVEHFRNFTRMRQEGGVFAQLRKNQVDANPLDVRQQSKTKDWEQSYVREGEQSRRIKVAEPKKLAARFDILKKEFGWNTMAATNRLDVDLDLPFQPVAGNRSYQDGLKNVKFSMSLRGKHIPLGVKHMIEKGLLETPAPDWLTSLPTTAATYFHVTKDKVSQTKPTPNLEEEDEEEEGEEEEGDNETEQQEMSGIETNQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N643</accession>
    <name>A0A1C7N643_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Putative PH domain-containing protein C19A8.02</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">A0J61_07366</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the YSP2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000493">
        <property type="protein sequence ID" value="OBZ84580.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N643"/>
    <dbReference type="FunCoup" id="A0A1C7N643">
        <property type="interactions" value="49"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N643"/>
    <dbReference type="InParanoid" id="A0A1C7N643"/>
    <dbReference type="OrthoDB" id="10070851at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140268">
        <property type="term" value="C:endoplasmic reticulum-plasma membrane contact site"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032934">
        <property type="term" value="F:sterol binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0120015">
        <property type="term" value="F:sterol transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032366">
        <property type="term" value="P:intracellular sterol transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.60">
        <property type="entry name" value="Arfaptin homology (AH) domain/BAR domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027267">
        <property type="entry name" value="AH/BAR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004148">
        <property type="entry name" value="BAR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051482">
        <property type="entry name" value="Cholesterol_transport"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004182">
        <property type="entry name" value="GRAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001849">
        <property type="entry name" value="PH_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031968">
        <property type="entry name" value="VASt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23319">
        <property type="entry name" value="GRAM DOMAIN CONTAINING 1B, ISOFORM E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23319:SF4">
        <property type="entry name" value="GRAM DOMAIN CONTAINING 1B, ISOFORM E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16746">
        <property type="entry name" value="BAR_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02893">
        <property type="entry name" value="GRAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00169">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16016">
        <property type="entry name" value="VASt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00568">
        <property type="entry name" value="GRAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00233">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103657">
        <property type="entry name" value="BAR/IMD domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50003">
        <property type="entry name" value="PH_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51778">
        <property type="entry name" value="VAST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="PH" evidence="8">
        <location>
            <begin position="308"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="domain" description="VASt" evidence="9">
        <location>
            <begin position="855"/>
            <end position="1020"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="745"/>
            <end position="771"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1018"/>
            <end position="1052"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="128"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="752"/>
            <end position="761"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="1020"/>
            <end position="1031"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="1033"/>
            <end position="1045"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006582"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51778"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OBZ84580.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="1208" mass="138246" checksum="DE29BA6BAC66CC6B" modified="2016-11-30" version="1">MLQPSLVSSSTNTLTIQDVVLDSPVWRSNLLHLQDQVDLFEKWVEGFMKALRSYLESIVKHNMQASNLCKKTLLTGLDGTLIDNTIAGNVVTRFATTLQFTIAYKTKMASDLEDTLLVPLQNIVKNDLKTFKETRKQFERTLDRYEAQLNRYYVLSKQKEASALREDAFQMFELRKSYVRSSVDFFSILVSFKTNLEQLLVSCFADALGAYIQDIDESAAACDHVRTKLNGWKQWMDENKMTSEYQLTKINNRCLELQDAYINKSKPDRSLKRYSTLSNDPMVAVSPTENTSDDDSNSNKEWVNTLKKGEKQGYLNCRIVSSRNRTPWSRRWFFLQQGWFGTCTVSTIQKEKGCVMVNDRIRITEATFRVFSESDRRFCFDLIHPRYTFHLQAETDHEMQQWLWAMEQAKEAELSSEDRVPQALLSPKANMFNKLSNKDNTSLVVAMSTSPLPSPTLEPSLSTTTSSLTSVMIRESQTVPLEETIPEVTNTNRLSLSSWGMPWLSTSMNAFSHNSTDDDANTTTSLFPITTSSNSSTTNNTTNNSNTNIIQNEQQDTNQLIVWPTKLELDTPKPNLPRYSAHLEESQRELRRYFDHVPEEETVLESLIASFYPSTEGYSGKMYLTQSRIWFYSCTFMTCVHVAVIPLAHIKSVHLENSTLILIETETDKFCFSVWLTSPATIVEKIKYAVEHHKTIPLDQFYDALRRIHPPKRKTKIPTSHVTTTMSNTLYTSVTPLTVQAQQQQPILIKQNPSTSTSNTTDEGEDTHSMANPEEDIASSLGTSFHSSPAQGALAAVAAKSQQRKSASKSALSSQPIVAETLTAEPSLLTEEADEWPSDVPKPQEKVSCRCKDHLEKIETDLVLDISPKVLFDLLFSDRGTLWHKLNQVKNNSPPVLSPWQQQERTMEYIMPVSNPLVKVKEADVIETQQIIEQQPYLSYVVMVSTKTPQLPYADAFVPCIKYCITYVSPTQSRLVCSMGVQWLKTIFVKGMVNRAAMKGMQETVQGLVSLLQQELASKSSKEPAKDEKQIPPKQSTKHQPQYDSQQHKKERKEKNIKWPSLWTWILCVLCMLSAIHQLYLQHKYQALVQENQTVSWRGVYLRDIEEQLIQREQSATRMNHSVYALFQEAKEKKDTKWSSRQHRIMAAEISIMKEKLGVLRFELLSSFRILNLIEHQLLENEYHNWVADQLLDCKEDAVCHLLRKEIT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N694</accession>
    <name>A0A1C7N694_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Homeobox protein HD-10</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">HD-10_1</name>
        <name evidence="9" type="ORF">A0J61_07332</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 5 6">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000488">
        <property type="protein sequence ID" value="OBZ84620.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N694"/>
    <dbReference type="STRING" id="101091.A0A1C7N694"/>
    <dbReference type="InParanoid" id="A0A1C7N694"/>
    <dbReference type="OrthoDB" id="6159439at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030154">
        <property type="term" value="P:cell differentiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00086">
        <property type="entry name" value="homeodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001356">
        <property type="entry name" value="HD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017970">
        <property type="entry name" value="Homeobox_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051000">
        <property type="entry name" value="Homeobox_DNA-bind_prot"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057939">
        <property type="entry name" value="TRF2_HOY1_PH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24324:SF5">
        <property type="entry name" value="HEMATOPOIETICALLY-EXPRESSED HOMEOBOX PROTEIN HHEX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24324">
        <property type="entry name" value="HOMEOBOX PROTEIN HHEX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00046">
        <property type="entry name" value="Homeodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24818">
        <property type="entry name" value="PH_TRF2_HOY1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00389">
        <property type="entry name" value="HOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00027">
        <property type="entry name" value="HOMEOBOX_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50071">
        <property type="entry name" value="HOMEOBOX_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 5 6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3 5 6" id="KW-0371">Homeobox</keyword>
    <keyword evidence="4 5 6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Homeobox" evidence="8">
        <location>
            <begin position="48"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="Homeobox" evidence="5">
        <location>
            <begin position="50"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="126"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="320"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="470"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="8"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="27"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="126"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="320"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="344"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="355"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="626"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OBZ84620.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="626" mass="70215" checksum="C24BCE2903859729" modified="2016-11-30" version="1" fragment="single">MTYLLNKSSQQSWSQQLSENNHHGDNNENSDNLISASNEEEETTGSSAPPVRKRTRATADQLSVLEDTFAVNVSPNSKLRKQLAEQLQMSERSIQIWFQNRRAKVKHMQKRAQMQMHQASIRAQLYQYHQQQQQQQQQQQQPPPPFGQPLLPMQTPYQQQPYYYNPAAARLAIPPRAQSVDAVQFHYNANINNRLATQTEAMFTPPSSVPPASLATVANTSYSTPPPMSYPQYFGQQQIATPWPSSAQDDIQLMRQSMPPQVYPYDLSGSIDSTTGLDFPEYIHGPASPSPGPLNAKSTIPTLVSVPDAGPTAVLTTSTVISDSNSSKHSLSPAPIEQPVPTIDPSSLIMTPSSESKDNTSEKDGFKSEKEEPVVVLPDEDDEEPKDLYLSATTLTIGTWHRLKMQETDLVCVYRPDTRIFAWHIVDGGCHFKMEVPQKAVSSIEFILDEHEALADVHFDISEPPLFYMESTTSTPPEKKKKKSEDTDSPSETLSSMWVQCSDFTEGKQASRFFRHTLKGISHNMKQELLALISNHEETRRLVHFIESTTAPIVHPYTATMYQPLIVDQQVPHHPHTHLFHPQQHLIPTTDESLLMQSAATGTGFNPVYWPGQANSEPIACELYMS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N727</accession>
    <name>A0A1C7N727_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Phospholipase/carboxylesterase/thioesterase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">A0J61_07011</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the AB hydrolase superfamily. AB hydrolase 2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000453">
        <property type="protein sequence ID" value="OBZ84933.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N727"/>
    <dbReference type="FunCoup" id="A0A1C7N727">
        <property type="interactions" value="350"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N727"/>
    <dbReference type="InParanoid" id="A0A1C7N727"/>
    <dbReference type="OrthoDB" id="437457at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052689">
        <property type="term" value="F:carboxylic ester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008474">
        <property type="term" value="F:palmitoyl-(protein) hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050565">
        <property type="entry name" value="LYPA1-2/EST-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003140">
        <property type="entry name" value="PLipase/COase/thioEstase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10655">
        <property type="entry name" value="LYSOPHOSPHOLIPASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10655:SF67">
        <property type="entry name" value="PHOSPHOLIPASE_CARBOXYLESTERASE SUPERFAMILY (AFU_ORTHOLOGUE AFUA_5G09340)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02230">
        <property type="entry name" value="Abhydrolase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Phospholipase/carboxylesterase/thioesterase" evidence="3">
        <location>
            <begin position="40"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006499"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02230"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OBZ84933.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="216" mass="23854" checksum="10732605B2B7241F" modified="2016-11-30" version="1">MQSISVKESAVDPKNKKATPPNPKKTKLQFDYSPSQDGIDHNLLILFHGLGDSKGPFARLGQQLKLPQTAIISIQAPEPVPYLDGCFQWYPSFDFLTGDLLTPTNPERLKGLIRTRQLIAELLHHLINDCGFQPPNIFLFGFSQGGTVALDTVLFGKIRNLGGVVSISGYLLEEQRADQKIGDGYAGYILITQGEKDKTIGSQSEAEKRVKSQEKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N7E8</accession>
    <name>A0A1C7N7E8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_06964</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000446">
        <property type="protein sequence ID" value="OBZ84991.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N7E8"/>
    <dbReference type="InParanoid" id="A0A1C7N7E8"/>
    <dbReference type="OrthoDB" id="2265153at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ84991.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="145" mass="16298" checksum="3560CFC3D6A1ACF3" modified="2016-11-30" version="1">MSQVYLSNQPNASEKRPIAYKTELPPTPSSSAISLFVNDQKEPAESFSEFSLQVPSNSSNYGSLSTEFSYTRANSLSTVSPNGDDESLYLLWTHQLLREKGLQPSSCIDNDDSYSIDSSITEVSQIETRMSQLYQPWWKSCFPMC</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N7X0</accession>
    <name>A0A1C7N7X0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Extragenic suppressor of kinetochore protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">ekc1_0</name>
        <name evidence="4" type="ORF">A0J61_06735</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SAPS family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000421">
        <property type="protein sequence ID" value="OBZ85213.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N7X0"/>
    <dbReference type="FunCoup" id="A0A1C7N7X0">
        <property type="interactions" value="603"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N7X0"/>
    <dbReference type="InParanoid" id="A0A1C7N7X0"/>
    <dbReference type="OrthoDB" id="295029at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019903">
        <property type="term" value="F:protein phosphatase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019888">
        <property type="term" value="F:protein phosphatase regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007587">
        <property type="entry name" value="SAPS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12634:SF8">
        <property type="entry name" value="FIERY MOUNTAIN, ISOFORM D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12634">
        <property type="entry name" value="SIT4 YEAST -ASSOCIATING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04499">
        <property type="entry name" value="SAPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="542"/>
            <end position="566"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="585"/>
            <end position="768"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="557"/>
            <end position="566"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="587"/>
            <end position="597"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="598"/>
            <end position="609"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="611"/>
            <end position="620"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="625"/>
            <end position="645"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="649"/>
            <end position="660"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="679"/>
            <end position="699"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OBZ85213.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="768" mass="88139" checksum="690A703A4C5122DC" modified="2016-11-30" version="1">MFWRFGFNSSTLDTLLDKEDVTLEEVLEEEDLLQEAKSMNPKLVEFLSKMDHVKALLNYIVATDLEETKRFKYPFLASEIIACEIQPIIDAIVMDHKDELLLPFWSYLDQPAPPRRKANSASKEEGIGLDSLQASYFCKTIGVLLSKYPIEMMTFIQSDPSNLDKILSHLQTSAVMDLLLTLVRMEELPEGKGVVKWLSNHGLLENLIDRLDPYLDNEEHSIAQQCICEIVRMSQTSLPESPSIGLNELIVQLKSESTIQKLAKYMLDSDAPNATSTLINGVGIIIDIIRHNNSDLENDPTVAALYEYQQQQQQQQSFQRAGVSLAEMLKVMGDHVADFTHLLLKPRSVRGPIHTTLGEMEPLGFERLKICELFAELLHCSNMSNLNHFNGSEEEQPKSTELSVGDYLKSKFVENKALPICVDLFFTFPWNNFLHYVIYDMLHQVFNGRMDVGLNRHLAISILKDGQLTDKIVVAQKANDEECAKPKGIRAGYMGHLTFISDEIMKLFEGYPETIVLEIKDDIDMEGWNAYCSHELKETKERDQLPLGGLRPNDDVPPSDEEDDEDVLEGTAAIQYSRFLAQRGEEGQFDEDDDDDADHWITGRDDFNRDYSYTSNNYTKNEQNLPEEEEEEEEYNSHDEEENDVTPDWTRNFSKFSESASLRRIPSHTEEEEEEYDDFDHLADAEELERRAALRRYKEQEEEDDFGDFESAADHAEQLDALPSQMENLDVNKKTPAQDVVRAVKTKEEDEQYLKQYQHDTDEQEGEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N8A8</accession>
    <name>A0A1C7N8A8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">SAP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_06651</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000412">
        <property type="protein sequence ID" value="OBZ85297.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N8A8"/>
    <dbReference type="InParanoid" id="A0A1C7N8A8"/>
    <dbReference type="OrthoDB" id="2290844at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="73"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="186"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="88"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="210"/>
            <end position="234"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ85297.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="265" mass="29572" checksum="5AC87950A0FD39AB" modified="2016-11-30" version="1">MKKTELIQLAKENKLPVSGTKNEIIIDLLTHQTAKIVGSTTPSSINVQPEQHQPEEDPVVNADWVNAFDMKVAQRRSSRKPFSPQTESNRESKPHPLNDAFKKTVLSPTFVSQAEERVEEEKAMDVKKELVDDELDGMDPLWVEAFALKVSSRDKRQKTQDTLSPMTSTELDPITITESAAIETKPMEAEPANVESSNTTPVETKPVHVDTNSMEQPTPTHSSHESSNPSNRQWTSAAIGSSMLIWYFGGEEGFSKLWNFFTSSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N8G2</accession>
    <name>A0A1C7N8G2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Vacuolar protein sorting-associated protein 27</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">vps27_0</name>
        <name evidence="14" type="ORF">A0J61_06576</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endosome membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
            <orientation evidence="1">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the VPS27 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000403">
        <property type="protein sequence ID" value="OBZ85373.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N8G2"/>
    <dbReference type="FunCoup" id="A0A1C7N8G2">
        <property type="interactions" value="124"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N8G2"/>
    <dbReference type="InParanoid" id="A0A1C7N8G2"/>
    <dbReference type="OrthoDB" id="957735at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010008">
        <property type="term" value="C:endosome membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033565">
        <property type="term" value="C:ESCRT-0 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032266">
        <property type="term" value="F:phosphatidylinositol-3-phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043130">
        <property type="term" value="F:ubiquitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006623">
        <property type="term" value="P:protein targeting to vacuole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043328">
        <property type="term" value="P:protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd15735">
        <property type="entry name" value="FYVE_spVPS27p_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd16979">
        <property type="entry name" value="VHS_Vps27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.40.10:FF:000105">
        <property type="entry name" value="WD repeat and FYVE domain-containing protein 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.1940">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008942">
        <property type="entry name" value="ENTH_VHS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003903">
        <property type="entry name" value="UIM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002014">
        <property type="entry name" value="VHS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049425">
        <property type="entry name" value="Vps27_GAT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000306">
        <property type="entry name" value="Znf_FYVE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017455">
        <property type="entry name" value="Znf_FYVE-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47794">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47794:SF1">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01363">
        <property type="entry name" value="FYVE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02809">
        <property type="entry name" value="UIM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00790">
        <property type="entry name" value="VHS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21356">
        <property type="entry name" value="Vps27_GAT-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00064">
        <property type="entry name" value="FYVE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00726">
        <property type="entry name" value="UIM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00288">
        <property type="entry name" value="VHS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48464">
        <property type="entry name" value="ENTH/VHS domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89009">
        <property type="entry name" value="GAT-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50330">
        <property type="entry name" value="UIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50179">
        <property type="entry name" value="VHS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50178">
        <property type="entry name" value="ZF_FYVE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0967">Endosome</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="8" id="KW-0862">Zinc</keyword>
    <keyword evidence="7 10" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="VHS" evidence="13">
        <location>
            <begin position="25"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="domain" description="FYVE-type" evidence="12">
        <location>
            <begin position="165"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="232"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="272"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="441"/>
            <end position="540"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="441"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="467"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="503"/>
            <end position="526"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008597"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00017753"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022753"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50178"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="OBZ85373.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="540" mass="61047" checksum="628E325B39C60D52" modified="2016-11-30" version="1">MSWWGQSAFEETIEKATSELLPGGQEDLVLNLDISDQIRSKKVNAKDAMRLLKKRLSHANPNVQLATLSLVDTCVKNGGDLFVREIASREFMDELVLILRRDSNPEVRNKILSIIQTWGLASKNKPTLSYMYDTYALLKAEGTSFPPVDVNADSILLETAAAPEWSDSDVCDRCRTPFTLTNRKHHCRNCGGTFCQQCSAKTMPLPKLGINESVRVCDGCYIKLKLEKASVQTATPKPAAIPPPSTNQTEDSDHFDDDMKRAIELSLKEAEQSKNSYGAGYVAPKEPEPQRETAPANDEEDDADLAAAIAASLRDLEIAQQPTKKTNTNELSSVEMENILLFSTLMDRVYASGGDVSNDTQINQLYTQIGTLQPKLVKNLNETIQKRNAFIELHEKLNMAVRAYDRLLEERLRGVRQQPSTYYLPEQQYQPQPLYHQAYYQPSPQQQQQQQQQPSAYYPTPSPHMATPTTPSQDYTNQQDMSQYYSAPPHYQLSPQVTDQHAYPQPQQQQQQQQPYPQQPQQPQQQHYTKPIDEAPLIDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N8M5</accession>
    <name>A0A1C7N8M5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Universal stress protein A-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_06650</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000412">
        <property type="protein sequence ID" value="OBZ85298.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N8M5"/>
    <dbReference type="STRING" id="101091.A0A1C7N8M5"/>
    <dbReference type="InParanoid" id="A0A1C7N8M5"/>
    <dbReference type="OrthoDB" id="843225at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd23659">
        <property type="entry name" value="USP_At3g01520-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006015">
        <property type="entry name" value="Universal_stress_UspA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006016">
        <property type="entry name" value="UspA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31964">
        <property type="entry name" value="ADENINE NUCLEOTIDE ALPHA HYDROLASES-LIKE SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31964:SF140">
        <property type="entry name" value="UNIVERSAL STRESS PROTEIN FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00582">
        <property type="entry name" value="Usp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01438">
        <property type="entry name" value="UNVRSLSTRESS"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52402">
        <property type="entry name" value="Adenine nucleotide alpha hydrolases-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UspA" evidence="2">
        <location>
            <begin position="31"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="174"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="174"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="186"/>
            <end position="196"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00582"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ85298.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="196" mass="21954" checksum="CAAC2310899B6EE9" modified="2016-11-30" version="1">MTSNNSSTLPPLQKTDTLVHSHPEEIPDLTRVVLICLDPDSAEVTFHWAMENFIEPHKDLVVLVHVRQIDIPVAPYINSTGYVDDVSAERREESHHLLRTYAEKLSKNKIACKAISMVGDPKLELLRKAKEIKSDVVLMGARKMGAIKRTLLGSVSDYLVHNCPCTVIVTKPEEVSHHEERRKSIASLTSNPDSTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-06-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N8T8</accession>
    <name>A0A1C7N8T8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_06447</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000389">
        <property type="protein sequence ID" value="OBZ85511.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N8T8"/>
    <dbReference type="InParanoid" id="A0A1C7N8T8"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ85511.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="93" mass="10620" checksum="0EDCFD316E012F7D" modified="2016-11-30" version="1">MTGHNLTEMTKYNKYSIAEHPTKFVDSECAEDLWLDGLIIQIFDCTRKARFSDSDFHNPHTLPIVHNGVSNVVLRFVGEIARFVPVFLNKVLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N8V6</accession>
    <name>A0A1C7N8V6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Kinesin-like protein unc-104</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">A0J61_06591</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="11">Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000405">
        <property type="protein sequence ID" value="OBZ85358.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N8V6"/>
    <dbReference type="InParanoid" id="A0A1C7N8V6"/>
    <dbReference type="OrthoDB" id="3176171at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008017">
        <property type="term" value="F:microtubule binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005546">
        <property type="term" value="F:phosphatidylinositol-4,5-bisphosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008574">
        <property type="term" value="F:plus-end-directed microtubule motor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047496">
        <property type="term" value="P:vesicle transport along microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd22705">
        <property type="entry name" value="FHA_KIF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01365">
        <property type="entry name" value="KISc_KIF1A_KIF1B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.200.20:FF:000001">
        <property type="entry name" value="Kinesin family member 1B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.850.10:FF:000047">
        <property type="entry name" value="Kinesin family protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.200.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.2520">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.850.10">
        <property type="entry name" value="Kinesin motor domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000253">
        <property type="entry name" value="FHA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022164">
        <property type="entry name" value="Kinesin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022140">
        <property type="entry name" value="Kinesin-like_KIF1-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032405">
        <property type="entry name" value="Kinesin_assoc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019821">
        <property type="entry name" value="Kinesin_motor_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001752">
        <property type="entry name" value="Kinesin_motor_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036961">
        <property type="entry name" value="Kinesin_motor_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008984">
        <property type="entry name" value="SMAD_FHA_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47117:SF10">
        <property type="entry name" value="KINESIN-LIKE PROTEIN KIF1B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47117">
        <property type="entry name" value="STAR-RELATED LIPID TRANSFER PROTEIN 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12473">
        <property type="entry name" value="DUF3694"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00498">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12423">
        <property type="entry name" value="KIF1B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00225">
        <property type="entry name" value="Kinesin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16183">
        <property type="entry name" value="Kinesin_assoc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00380">
        <property type="entry name" value="KINESINHEAVY"/>
    </dbReference>
    <dbReference type="SMART" id="SM00240">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00129">
        <property type="entry name" value="KISc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49879">
        <property type="entry name" value="SMAD/FHA domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50006">
        <property type="entry name" value="FHA_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00411">
        <property type="entry name" value="KINESIN_MOTOR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50067">
        <property type="entry name" value="KINESIN_MOTOR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8 12" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="10" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="5" id="KW-0493">Microtubule</keyword>
    <keyword evidence="9 11" id="KW-0505">Motor protein</keyword>
    <keyword evidence="6 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Kinesin motor" evidence="15">
        <location>
            <begin position="5"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="domain" description="FHA" evidence="14">
        <location>
            <begin position="525"/>
            <end position="576"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="395"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="617"/>
            <end position="643"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="687"/>
            <end position="717"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1131"/>
            <end position="1166"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="12">
        <location>
            <begin position="734"/>
            <end position="772"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="402"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="1132"/>
            <end position="1143"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="101"/>
            <end position="108"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="non-terminal residue" evidence="16">
        <location>
            <position position="1555"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00020751"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00283"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50067"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="OBZ85358.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="1555" mass="176323" checksum="AFC6CF7D4CEA481A" modified="2016-11-30" version="1" fragment="single">MSGGNIKVVVRCRPFNSREIARGAVGLIRMEGNQTIISRPPDQRTGKESEDVKAFTFDKSYWSVDKNHPSYADQQTVYNDLGEELLNHAFDGYNCCIFAYGQTGAGKSYSMMGYGEDKGITPRTCSELFNRINSNSDPNLTYRVEVSYIEIYNEKVRDLLNPKNKGNLKVREHPSLGPYVEDLSRLVVTSFDDIEHLMDEGNKARTVAATNMNETSSRSHAVFTLFLTQKRLDDLTKLETEKVARISLVDLAGSERANSTGATGARLKEGANINRSLTTLGKVIAGLAEQSQLEGKRGKKKEAFIPYRDSVLTWLLKDSLGGNSKTAMIAAISQADYDETLSTLRYADQAKKIKNKAIVNEDPNAKLIRDLKDELELLRDRLRTYAPEEVEQLTAASAYKSPGSNSTSNLPRNPTPAPTSSKKVPEFEITDSTGKKKKMSKEEIVEQLQSSEKLLANLNESWEEKLKKTEEIHLEREKSLKELGITIEKNDMGVYTPKTIPFIVNLNEDPLMSECLMYQIKPGLTKLGRQDSDVPADIRLSGSNIQDEHCVFENKNGVVTLLPNPESLTMVNGRRITEPHQLKSGYRIILGYYHIFRFNNPEEVRKERDLHKVAIENSMQGATSTADEEDARPDSPSTESTVGSEVIDWNFARREAVLAYYSADNNFEAFKDDELEKLYDGIAKIRNSRRSRSESRADNNDDDDSSTTRDSFRNSTSATMVEDGLESVCTDLSVAQSEVLEEKIKQEKERLQKELDNQKRLFEAKINRMSRQYSQQHSDFALPTYTPHQIALIEKVLGKWRQLRTVDMAEVVLTNAVMLKEANIISRELNKEILYQFTVIEDDPFSNPLSYHEPTSLLHQFETDEDTMLVSTPKPCVGVRVIDKKNQVIYIWSLEKLKQRLHKMRNLYNFMDKPLYRKHFNWEDPFFENPCPKYTFIGAALVSARNLITQQAYETCCEIICRSTGQTRGQLRVLISPIARSVAIRNESSRLSLLDNTQLVFPENNGFVEDIDDEEEEDQQHTHDEHATLQVGQNLLFEIKLIEFSGINESEFTDVHIQFRLSSFGGIPSYSPSEKTFATEPANYFESNPVQLGYSQTLSLTVNETVLKTLKHGCIPFEVFGQAQPRVLIQQERWDDQREKPPRLPELLSHRKSSSDHASLRSSSGSSSDITIASIERRSEEELLAAERHDIVAWIEVRELSPSGEYTPVQLTAKSPMDKGYFTIRQGLQRRFCFTLCHTSGRQFQWTKITKASVGHVRLLDGKGRILESPAQENIPIKLLSKQQVFYNSDGTSRLTAQGAWDSSQHECIFLNRLTEANSRVILNLRWEVAVESCEKPIHFNMDVAFQIQGRDRSIGGSKFISFRKLLYSNGRQLSKYSGVFLVHLKPPMTRNLSQLWRLNTASKYVHGEEFLGTWRPRGVSLVNDYRQIQDSISRKLQVAFTRQVLELKQTENDTLLSPTSISSLSTAVTKDASDTDEKQALLKKIIDLWTLKLGTDQEIIISQDPPILLENNGPLTQEPLSISKLIAEVELVAQPANISKKGFLLYQEDASQDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N901</accession>
    <name>A0A1C7N901_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">pectinesterase</fullName>
            <ecNumber evidence="3">3.1.1.11</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">PECS-2.1</name>
        <name evidence="8" type="ORF">A0J61_06862</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Glycan metabolism; pectin degradation; 2-dehydro-3-deoxy-D-gluconate from pectin: step 1/5.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the pectinesterase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.11" evidence="3"/>
    <dbReference type="EMBL" id="LUGH01000435">
        <property type="protein sequence ID" value="OBZ85086.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N901"/>
    <dbReference type="STRING" id="101091.A0A1C7N901"/>
    <dbReference type="InParanoid" id="A0A1C7N901"/>
    <dbReference type="OrthoDB" id="1546079at2759"/>
    <dbReference type="UniPathway" id="UPA00545">
        <property type="reaction ID" value="UER00823"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030599">
        <property type="term" value="F:pectinesterase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042545">
        <property type="term" value="P:cell wall modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045490">
        <property type="term" value="P:pectin catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.20.10">
        <property type="entry name" value="Single-stranded right-handed beta-helix, Pectin lyase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012334">
        <property type="entry name" value="Pectin_lyas_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011050">
        <property type="entry name" value="Pectin_lyase_fold/virulence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000070">
        <property type="entry name" value="Pectinesterase_cat"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31321">
        <property type="entry name" value="ACYL-COA THIOESTER HYDROLASE YBHC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31321:SF58">
        <property type="entry name" value="METHYLESTERASE, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01095">
        <property type="entry name" value="Pectinesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51126">
        <property type="entry name" value="Pectin lyase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0063">Aspartyl esterase</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5011118796" description="pectinesterase" evidence="6">
        <location>
            <begin position="21"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="domain" description="Pectinesterase catalytic" evidence="7">
        <location>
            <begin position="23"/>
            <end position="319"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008891"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01095"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OBZ85086.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="358" mass="39356" checksum="B15EEFBE5C568482" modified="2016-11-30" version="1">MKYFYGTLFALLAYATLSLAATVNVCPTCTYKTVSAALTSIPGGSTEYRIDIAPGVYHETFTISRSNIILAKKGDGEVVIEYAIGHDTQGSHGNTTEMAVVTITGSNIRFYDITIANTYKQTFNIANVALSVKGKQVGFYRSKIYGFQDTLLINEGATVYFKSCYVEGNVDFIYGYGTGYFQECNIASNGVGYVTAQKRRTPNSEGGLYFNGCYLIPTLPSGPIAKSANPSHSFTRTSRKDNTSYLGRPWNENARVIFISSQLGSHIRPEGWSIWSRIRPNISNVLFGEYGNSGPRSSLAKRKYTTKLTPAQAAQYSVGGVFGSTSWIDTTSSTSIKTFDNFALFYYVSLKIECYKAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N956</accession>
    <name>A0A1C7N956_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Reverse transcriptase zinc-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_06287</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000373">
        <property type="protein sequence ID" value="OBZ85663.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="InParanoid" id="A0A1C7N956"/>
    <dbReference type="OrthoDB" id="2290079at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ85663.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="533" mass="60570" checksum="AAF57800BD91EB9C" modified="2016-11-30" version="1" fragment="single">VNYHKSVVFPLSRIPVPNLPLRSSVQEKGLRWYDHRSHGFLRYLGYPIWLAPHQQTSYVEGMIRTIKASIAIHSGRQISVYARALIANSLILSKLWHVLRLTPLPANVLNKINSLTYQFVSHGFFPKIRRSILHLPKASGGLGLLDIRAQRLSLQLRCLSPSLPTASSVPMTPFLYRMMCWLLQTLSNSPSVMIPILFSSSRSSALTDTDSPFAAILEAVDAIPKSPSHEAFPNLPTCLALPLKDICAIPEASSFVFSRTMRXFXVTDIFITDLASNRLRFRSXPECQFPRLLSRFKKAVAQADLILPPFIAVRMLXSISVTTPESLDFSPFSDLLSYQAVPLSFLNKRALKQLFKDVVASLVPSSLPAIPPSRWKLFLSTPMDGATRTLWYRLIHDKISSKNSLYRLLPDVIGDDRCHYCYNTETPCRMFFTCGIKSHVWYRGFSHHIGSPNRVLLSVLFENFRLLSFPLYTISDYSIKLHIYQMMGVFVFSIWSAQWREHFSAIPFLSDRVFCNILKKVHSLNQITSLSLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N993</accession>
    <name>A0A1C7N993_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Glutaredoxin-1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">GRX1</name>
        <name evidence="6" type="ORF">A0J61_08036</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000584">
        <property type="protein sequence ID" value="OBZ83914.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N993"/>
    <dbReference type="FunCoup" id="A0A1C7N993">
        <property type="interactions" value="286"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N993"/>
    <dbReference type="InParanoid" id="A0A1C7N993"/>
    <dbReference type="OrthoDB" id="418495at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015038">
        <property type="term" value="F:glutathione disulfide oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004602">
        <property type="term" value="F:glutathione peroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034599">
        <property type="term" value="P:cellular response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd03419">
        <property type="entry name" value="GRX_GRXh_1_2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.30.10:FF:000026">
        <property type="entry name" value="Glutaredoxin 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011767">
        <property type="entry name" value="GLR_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002109">
        <property type="entry name" value="Glutaredoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011899">
        <property type="entry name" value="Glutaredoxin_euk/vir"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014025">
        <property type="entry name" value="Glutaredoxin_subgr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02180">
        <property type="entry name" value="GRX_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45694">
        <property type="entry name" value="GLUTAREDOXIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45694:SF18">
        <property type="entry name" value="GLUTAREDOXIN-1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00462">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00160">
        <property type="entry name" value="GLUTAREDOXIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00195">
        <property type="entry name" value="GLUTAREDOXIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51354">
        <property type="entry name" value="GLUTAREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="2" id="KW-0249">Electron transport</keyword>
    <keyword evidence="4" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Glutaredoxin" evidence="5">
        <location>
            <begin position="30"/>
            <end position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OBZ83914.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="112" mass="12530" checksum="C1A632CE136E3314" modified="2016-11-30" version="1">MGGLQSKQLSPEEMSKIQQVVEEIINNNKIAVFSKSYCPYCQKAKKLLQDLGYEFFAIELDNESDGAAIQQYLQEKTGQRTVPNIFVNQQHVGGCDDLFAAKSSGKLQKLVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N9V0</accession>
    <name>A0A1C7N9V0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Ubiquitin domain-containing protein DSK2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">DSK2</name>
        <name evidence="4" type="ORF">A0J61_06086</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000351">
        <property type="protein sequence ID" value="OBZ85857.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N9V0"/>
    <dbReference type="FunCoup" id="A0A1C7N9V0">
        <property type="interactions" value="477"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N9V0"/>
    <dbReference type="InParanoid" id="A0A1C7N9V0"/>
    <dbReference type="OrthoDB" id="267397at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031593">
        <property type="term" value="F:polyubiquitin modification-dependent protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006511">
        <property type="term" value="P:ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd14399">
        <property type="entry name" value="UBA_PLICs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd16106">
        <property type="entry name" value="Ubl_Dsk2p_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.20.90:FF:000205">
        <property type="entry name" value="2'-5'-oligoadenylate synthase-like protein 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.10:FF:000079">
        <property type="entry name" value="Ubiquitin family protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.10">
        <property type="entry name" value="DNA helicase RuvA subunit, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006636">
        <property type="entry name" value="STI1_HS-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015940">
        <property type="entry name" value="UBA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009060">
        <property type="entry name" value="UBA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015496">
        <property type="entry name" value="Ubiquilin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000626">
        <property type="entry name" value="Ubiquitin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019954">
        <property type="entry name" value="Ubiquitin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019956">
        <property type="entry name" value="Ubiquitin_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10677:SF3">
        <property type="entry name" value="FI07626P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10677">
        <property type="entry name" value="UBIQUILIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00627">
        <property type="entry name" value="UBA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00240">
        <property type="entry name" value="ubiquitin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23195">
        <property type="entry name" value="UBQLN1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00348">
        <property type="entry name" value="UBIQUITIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00727">
        <property type="entry name" value="STI1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00165">
        <property type="entry name" value="UBA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00213">
        <property type="entry name" value="UBQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46934">
        <property type="entry name" value="UBA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50030">
        <property type="entry name" value="UBA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00299">
        <property type="entry name" value="UBIQUITIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50053">
        <property type="entry name" value="UBIQUITIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ubiquitin-like" evidence="3">
        <location>
            <begin position="4"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="domain" description="UBA" evidence="2">
        <location>
            <begin position="264"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="73"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="78"/>
            <end position="102"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50030"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OBZ85857.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="310" mass="33079" checksum="EB275CFE33F6CB9D" modified="2016-11-30" version="1">MSSINVNIKSSSDKKFIITIETEKTVLDLKTAIAEQTEVPADRQRLIYSGRVLKDHDTLADCKIADGNTVHMVKGSQPATTTTTTPNTNTTPSTTPSTAPNTPANPFAGLAGMPADSQSNPFNMFGAGFGAGALGNSFGAMDPNMTNQMLQNPMFAQYMSSVLQNPAILDNIIQTNPQLASMGPEIRNMMQSPEFRQMLSNPDMIRQMASMASLMQNNGLGTTSEPANPFASLGNAPAIDPQLQQRMAALFGGGGGASPTDSRPPEERFQVQLQQLNEMGFWDAAKNIRALTATGGNVNAAIEMLFSDNI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NAH8</accession>
    <name>A0A1C7NAH8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Coiled-coil domain-containing protein 25</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">CCDC25</name>
        <name evidence="4" type="ORF">A0J61_06246</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CCDC25 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000368">
        <property type="protein sequence ID" value="OBZ85709.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NAH8"/>
    <dbReference type="STRING" id="101091.A0A1C7NAH8"/>
    <dbReference type="InParanoid" id="A0A1C7NAH8"/>
    <dbReference type="OrthoDB" id="200398at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039730">
        <property type="entry name" value="Jlp2/Ccd25"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008532">
        <property type="entry name" value="NFACT_RNA-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13049:SF2">
        <property type="entry name" value="COILED-COIL DOMAIN-CONTAINING PROTEIN 25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13049">
        <property type="entry name" value="DUF814-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05670">
        <property type="entry name" value="NFACT-R_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NFACT RNA-binding" evidence="3">
        <location>
            <begin position="8"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="134"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="134"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="182"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008998"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF05670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OBZ85709.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="182" mass="21362" checksum="A85A8302E08D4131" modified="2016-11-30" version="1" fragment="single">MGKDKYESFHVDKMSSAHVYVRLQPGQTWLDIPDEVVDDCAQLVKANSIEGNKKNGITVIYTPWDNLKKTPGMETGQVTFHNNKKVKRVFVEKRLNEVVNRLNKTKVERFPDLMQEKINRDKIDRLKARQSEFAEKERARQLAEEKKRAEQEMSDLFDPNQMKSNWRDTEVDDINAAEEDFM</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NAJ0</accession>
    <name>A0A1C7NAJ0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">rhizopuspepsin</fullName>
            <ecNumber evidence="3">3.4.23.21</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">PEP4</name>
        <name evidence="14" type="ORF">A0J61_05921</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Hydrolysis of proteins with broad specificity similar to that of pepsin A, preferring hydrophobic residues at P1 and P1'. Clots milk and activates trypsinogen. Does not cleave 4-Gln-|-His-5, but does cleave 10-His-|-Leu-11 and 12-Val-|-Glu-13 in B chain of insulin.</text>
            <dbReference type="EC" id="3.4.23.21"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the peptidase A1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.23.21" evidence="3"/>
    <dbReference type="EMBL" id="LUGH01000335">
        <property type="protein sequence ID" value="OBZ86030.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NAJ0"/>
    <dbReference type="FunCoup" id="A0A1C7NAJ0">
        <property type="interactions" value="57"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NAJ0"/>
    <dbReference type="InParanoid" id="A0A1C7NAJ0"/>
    <dbReference type="OrthoDB" id="771136at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004190">
        <property type="term" value="F:aspartic-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.70.10:FF:000149">
        <property type="entry name" value="Uncharacterized protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.70.10:FF:000002">
        <property type="entry name" value="Vacuolar aspartic proteinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.70.10">
        <property type="entry name" value="Acid Proteases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001461">
        <property type="entry name" value="Aspartic_peptidase_A1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001969">
        <property type="entry name" value="Aspartic_peptidase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033121">
        <property type="entry name" value="PEPTIDASE_A1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021109">
        <property type="entry name" value="Peptidase_aspartic_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47966">
        <property type="entry name" value="BETA-SITE APP-CLEAVING ENZYME, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47966:SF51">
        <property type="entry name" value="BETA-SITE APP-CLEAVING ENZYME, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00026">
        <property type="entry name" value="Asp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00792">
        <property type="entry name" value="PEPSIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50630">
        <property type="entry name" value="Acid proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00141">
        <property type="entry name" value="ASP_PROTEASE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51767">
        <property type="entry name" value="PEPTIDASE_A1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 11" id="KW-0064">Aspartyl protease</keyword>
    <keyword evidence="7 10" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="8" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="6 11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 11" id="KW-0645">Protease</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="12" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="12">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008889575" description="rhizopuspepsin" evidence="12">
        <location>
            <begin position="21"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase A1" evidence="13">
        <location>
            <begin position="76"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="active site" evidence="9">
        <location>
            <position position="94"/>
        </location>
    </feature>
    <feature type="active site" evidence="9">
        <location>
            <position position="279"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="10">
        <location>
            <begin position="107"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="10">
        <location>
            <begin position="313"/>
            <end position="346"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001130"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013205"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022750"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR601461-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR601461-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU000454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51767"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="OBZ86030.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="390" mass="43194" checksum="B1BB1B38838B5E7F" modified="2016-11-30" version="1">MRFFALSAVVLTVCSVWTEAAMTRIPLKKHQETPAERLQRYSHTGEYLVQKYFKGQQSREVDTFQRQADGSASHGYYGEIQLGSPPQPFTVVFDTGSSNLWVPSTHCNSIACFLHKRYDSGKSQTFSENGTEFSIRYGTGSLEGFISEDTLTVGGIKVDGQGFAESVKEPGFTFAFAKFDGIFGLGYDTISVKHTVPPFYHMVNRDLVDEPLFSVWLNSFEEGGENGGELVFGGSDPSHYTGDIVWSDIRRKGYWEITLENVKFGGDYVDLDPVGAAIDTGSSLLVVPTTIADLINHELGAEKNWAGQYVLDCGRISELPEFCLTFSGKDFCLSAEDYVLNVQNQCISGFMGMDIPEPAGPLWIIGDVFLRKYYSIYDLGNDRVGLAKAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NAZ2</accession>
    <name>A0A1C7NAZ2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">A0J61_05690</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000315">
        <property type="protein sequence ID" value="OBZ86253.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NAZ2"/>
    <dbReference type="InParanoid" id="A0A1C7NAZ2"/>
    <dbReference type="OrthoDB" id="8922241at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000100">
        <property type="entry name" value="Zinc finger 45-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="7">
        <location>
            <begin position="83"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="99"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="105"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="6">
        <location>
            <begin position="128"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="155"/>
            <end position="170"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OBZ86253.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="217" mass="24144" checksum="F6F541B9D1E907C6" modified="2016-11-30" version="1">MNKVNSQHSPLNHHNKDFSPPPLISLSISSDHVSPIKEQFIMKIDSQQKSTTPVSPTQDFSSLFGQFSLKTVPSSPYENQKIFTCIECGQTFNRAHNLKSHKATHSATKPFQVNTKTLPNPFLSPDQPTIPSPTLPPPILSSSSSSSPPLPSPKTSPSKTSLPPFLLPFSNSTTDQDEIDVLRQRIHDLEVENRVLRSLLCNKEEDDLSKPKRQRSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NB80</accession>
    <name>A0A1C7NB80_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="10">E3 ubiquitin-protein ligase MARCH5</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">march5</name>
        <name evidence="10" type="ORF">A0J61_05564</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000303">
        <property type="protein sequence ID" value="OBZ86385.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NB80"/>
    <dbReference type="FunCoup" id="A0A1C7NB80">
        <property type="interactions" value="12"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NB80"/>
    <dbReference type="InParanoid" id="A0A1C7NB80"/>
    <dbReference type="OrthoDB" id="5817083at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011016">
        <property type="entry name" value="Znf_RING-CH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46283">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE MARCH5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12906">
        <property type="entry name" value="RINGv"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00744">
        <property type="entry name" value="RINGv"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51292">
        <property type="entry name" value="ZF_RING_CH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4" id="KW-0863">Zinc-finger</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="132"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="230"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="302"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="340"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="domain" description="RING-CH-type" evidence="9">
        <location>
            <begin position="47"/>
            <end position="112"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51292"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OBZ86385.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="381" mass="43793" checksum="8D7293A5F7888429" modified="2016-11-30" version="1">MSYFRYPGSSSFVDEASLYIYRPIRGLDDSQLSFEEEDKMDNFTKLRESTDNKRCWICFGEDADSEGKWVFPCRCSLVSHEQCLLDWIAENQKNTPLKKVACPQCATKYVLTERQSIPLALMSIADNLVRIAAPYLTVLGLGCSMLITSSTLGAHVILTVFGAKDGEQLIGNPALWTWKTWLGLPSIPVALIASRSKWADHVLPATTLFLLKMTTIPHPLKLTWPPSPTVVFGLLPWMRLLYNNIYLVFQRKLLNQLIRSQQRERSDHNNALEEVEITEGADSDREANQDADILFNREGRNMSVIVIGALLWPTIGSIMGRYLSHSKLIRQYFPEQFQRTVLGGCLFVVAKDMANLYYRYERIRRKRTRHVLNYNERKFRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NBB9</accession>
    <name>A0A1C7NBB9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Protein RTF2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">RTFDC1</name>
        <name evidence="3" type="ORF">A0J61_05525</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the rtf2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000300">
        <property type="protein sequence ID" value="OBZ86432.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NBB9"/>
    <dbReference type="FunCoup" id="A0A1C7NBB9">
        <property type="interactions" value="839"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NBB9"/>
    <dbReference type="InParanoid" id="A0A1C7NBB9"/>
    <dbReference type="OrthoDB" id="247013at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006274">
        <property type="term" value="P:DNA replication termination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd16653">
        <property type="entry name" value="RING-like_Rtf2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006735">
        <property type="entry name" value="Rtf2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027799">
        <property type="entry name" value="Rtf2_RING-finger"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12775">
        <property type="entry name" value="PROTEIN C20ORF43 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12775:SF0">
        <property type="entry name" value="REPLICATION TERMINATION FACTOR 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04641">
        <property type="entry name" value="Rtf2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="189"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="241"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="189"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="210"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="247"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="268"/>
            <end position="278"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ86432.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="278" mass="30962" checksum="E626C22D9EB75D2B" modified="2016-11-30" version="1">MGNDGGSIPRRIELVKEKARDILLNPDIERAAAWLYCALSKLLLEQPVVSCGLGKLYNQDAILEYLLNPNTYGDGDKICSHITSVKDTIKLNLTPNPAYNLKVNNDSATMGNLEKDIKSKFICPLSMKEMNGKHRFVYLNTCGCTFAEQALKEVPSAECLTCGKPFEADNIVVINPTKEEQEVMRKKLEEKKAKARAEKKSKSSKKKRKREDVDAERSVKKTVIHSSAASAVMDKVAQDLADKNKKTQMSSAVKSIFSSSEKKEANGNYLTKGTFTRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NBG9</accession>
    <name>A0A1C7NBG9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="17">DASH complex subunit DUO1</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="18">Outer kinetochore protein DUO1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="20" type="ORF">A0J61_05846</name>
    </gene>
    <organism evidence="20 21">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="20 21" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="20 21">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Chromosome</location>
            <location evidence="3">Centromere</location>
            <location evidence="3">Kinetochore</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
            <location evidence="2">Cytoskeleton</location>
            <location evidence="2">Spindle</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the DASH complex DUO1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="20">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000328">
        <property type="protein sequence ID" value="OBZ86099.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NBG9"/>
    <dbReference type="STRING" id="101091.A0A1C7NBG9"/>
    <dbReference type="InParanoid" id="A0A1C7NBG9"/>
    <dbReference type="OrthoDB" id="5599235at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042729">
        <property type="term" value="C:DASH complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072686">
        <property type="term" value="C:mitotic spindle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007059">
        <property type="term" value="P:chromosome segregation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000278">
        <property type="term" value="P:mitotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013960">
        <property type="entry name" value="DASH_Duo1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28216">
        <property type="entry name" value="DASH COMPLEX SUBUNIT DUO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28216:SF1">
        <property type="entry name" value="DASH COMPLEX SUBUNIT DUO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08651">
        <property type="entry name" value="DASH_Duo1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="15" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="7" id="KW-0132">Cell division</keyword>
    <keyword evidence="16" id="KW-0137">Centromere</keyword>
    <keyword evidence="5" id="KW-0158">Chromosome</keyword>
    <keyword evidence="10" id="KW-0159">Chromosome partition</keyword>
    <keyword evidence="12" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="13" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="11" id="KW-0995">Kinetochore</keyword>
    <keyword evidence="8" id="KW-0493">Microtubule</keyword>
    <keyword evidence="9" id="KW-0498">Mitosis</keyword>
    <keyword evidence="14" id="KW-0539">Nucleus</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="19">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="19">
        <location>
            <begin position="126"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="19">
        <location>
            <begin position="132"/>
            <end position="148"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004629"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005366"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022838"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00044152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00044358"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="OBZ86099.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="158" mass="17882" checksum="582366B54BA006AB" modified="2016-11-30" version="1">MVSQGNNENRFRQPLPITPLPATPIHATPSHRQSTALRIAGRRSTFLVAPEDLSKPPIENPNNSSAYNEQLRQEYETLKSLNSTLETVIESTKGTSLKMKDFGDSVKQASHLLDMWISVQKRAQDTYSVMEEMSRESTKKRSAAHDNRNTANKKKRED</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NBK6</accession>
    <name>A0A1C7NBK6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_05524</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000300">
        <property type="protein sequence ID" value="OBZ86431.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NBK6"/>
    <dbReference type="InParanoid" id="A0A1C7NBK6"/>
    <dbReference type="OrthoDB" id="2355621at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ86431.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="86" mass="9297" checksum="2A97E0674623AFCA" modified="2016-11-30" version="1">MKHFLRSHKDNSTTSTPAHSNNATPITSPTGSIINVDATIQPVASDRYYNDPMRTGRKPDFVGGFFDPMGGYGSYTVSRDVTNTGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NBL8</accession>
    <name>A0A1C7NBL8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Serine palmitoyltransferase small subunit B</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">Protein ADMP</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="10">Small subunit of serine palmitoyltransferase B</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">A0J61_05504</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Component of the serine palmitoyltransferase multisubunit enzyme (SPT) that catalyzes the initial and rate-limiting step in sphingolipid biosynthesis by condensing L-serine and activated acyl-CoA (most commonly palmitoyl-CoA) to form long-chain bases. The SPT complex is composed of SPTLC1, SPTLC2 or SPTLC3 and SPTSSA or SPTSSB. Within this complex, the heterodimer consisting of SPTLC1 and SPTLC2/SPTLC3 forms the catalytic core. Within the SPT complex, SPTSSB stimulates the catalytic activity and plays a role in substrate specificity. SPT complexes with this subunit showing a preference for longer acyl-CoAs. The SPTLC1-SPTLC2-SPTSSB complex shows a strong preference for C18-CoA substrate, while the SPTLC1-SPTLC3-SPTSSB isozyme displays an ability to use a broader range of acyl-CoAs, without apparent preference.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2">Lipid metabolism.</text>
    </comment>
    <comment type="subunit">
        <text evidence="13">Component of the serine palmitoyltransferase (SPT) complex, which is composed of SPTLC1, SPTLC2 or SPTLC3 and SPTSSA or SPTSSB. The heterodimer consisting of SPTLC1 and SPTLC2/SPTLC3 forms the catalytic core of the enzyme, while SPTSSA or SPTSSB subunits determine substrate specificity. SPT also interacts with ORMDL proteins, especially ORMDL3, which negatively regulate SPT activity in the presence of ceramides.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the SPTSS family. SPTSSB subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000298">
        <property type="protein sequence ID" value="OBZ86451.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NBL8"/>
    <dbReference type="STRING" id="101091.A0A1C7NBL8"/>
    <dbReference type="InParanoid" id="A0A1C7NBL8"/>
    <dbReference type="OrthoDB" id="202672at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024512">
        <property type="entry name" value="Ser_palmitoyltrfase_ssu-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28612">
        <property type="entry name" value="SERINE PALMITOYLTRANSFERASE SMALL SUBUNIT B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28612:SF1">
        <property type="entry name" value="SERINE PALMITOYLTRANSFERASE SMALL SUBUNIT B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11779">
        <property type="entry name" value="SPT_ssu-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="6" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="7 14" id="KW-0472">Membrane</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 14" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 14" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="33"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00038059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00041140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00041982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00042334"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00045772"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00046416"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="OBZ86451.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="69" mass="8020" checksum="3EAF701095B5EBFA" modified="2016-11-30" version="1">MSVFNAFSEYLSKKKYQYELQTALYMLEPWEKALFNSLALCLFVVSAITVYHFITPLYTATAVDMLSQH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NCF3</accession>
    <name>A0A1C7NCF3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Nascent polypeptide-associated complex subunit alpha</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">Alpha-NAC</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">Nacalpha</name>
        <name evidence="6" type="ORF">A0J61_05515</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the NAC-alpha family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000299">
        <property type="protein sequence ID" value="OBZ86439.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NCF3"/>
    <dbReference type="FunCoup" id="A0A1C7NCF3">
        <property type="interactions" value="584"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NCF3"/>
    <dbReference type="InParanoid" id="A0A1C7NCF3"/>
    <dbReference type="OrthoDB" id="3169036at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005854">
        <property type="term" value="C:nascent polypeptide-associated complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd22054">
        <property type="entry name" value="NAC_NACA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd14358">
        <property type="entry name" value="UBA_NAC_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.10:FF:000006">
        <property type="entry name" value="Putative nascent polypeptide-associated complex subunit alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.10">
        <property type="entry name" value="DNA helicase RuvA subunit, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.70.30">
        <property type="entry name" value="Nascent polypeptide-associated complex domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016641">
        <property type="entry name" value="EGD2/NACA0like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044034">
        <property type="entry name" value="NAC-like_UBA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038187">
        <property type="entry name" value="NAC_A/B_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002715">
        <property type="entry name" value="Nas_poly-pep-assoc_cplx_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21713">
        <property type="entry name" value="NASCENT POLYPEPTIDE ASSOCIATED COMPLEX ALPHA SUBUNIT-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01849">
        <property type="entry name" value="NAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19026">
        <property type="entry name" value="UBA_HYPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF015901">
        <property type="entry name" value="NAC_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01407">
        <property type="entry name" value="NAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51151">
        <property type="entry name" value="NAC_AB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAC-A/B" evidence="5">
        <location>
            <begin position="7"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="77"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="90"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="102"/>
            <end position="111"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009882"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00014437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00030300"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OBZ86439.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="154" mass="16477" checksum="00F5DCFFED39CAC2" modified="2016-11-30" version="1">MSDSIQSRGEQKARKAILSLGLKPVAGINRVTFTRGRTLVYAIANPEVFKSTNSDTHIVFGEMQVEDMAARAQQAALEQQLAAEAEKTGEAAPEAAATSEAAAEEDDEEVDATGVEEKDIELVVSQANVSRSKAVKALKNNNNDVVNAIMELTM</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NCX3</accession>
    <name>A0A1C7NCX3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_05090</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000265">
        <property type="protein sequence ID" value="OBZ86868.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NCX3"/>
    <dbReference type="InParanoid" id="A0A1C7NCX3"/>
    <dbReference type="OrthoDB" id="9986409at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="34"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="73"/>
            <end position="94"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ86868.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="103" mass="11742" checksum="D6D2385DFA0B8CE0" modified="2016-11-30" version="1">MFQTRLADSRLVLTVVYVLFGAWAYWGFREDKAYYRATFIPVSEYLCVYFALGVGKLTQYTLQYIPQSLRKTLIFISALATTVCLTVGLALTLAGNLKVYNDY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-06-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7ND20</accession>
    <name>A0A1C7ND20_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_04945</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000254">
        <property type="protein sequence ID" value="OBZ87003.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7ND20"/>
    <dbReference type="InParanoid" id="A0A1C7ND20"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ87003.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="28" mass="3414" checksum="533AD914488AF0F3" modified="2016-11-30" version="1">MISIKQERSWFPRHRSLNRGMTVTILQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7ND39</accession>
    <name>A0A1C7ND39_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Oligopeptide transporter 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">OPT1</name>
        <name evidence="11" type="ORF">A0J61_04921</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the oligopeptide OPT transporter family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000252">
        <property type="protein sequence ID" value="OBZ87027.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7ND39"/>
    <dbReference type="FunCoup" id="A0A1C7ND39">
        <property type="interactions" value="10"/>
    </dbReference>
    <dbReference type="InParanoid" id="A0A1C7ND39"/>
    <dbReference type="OrthoDB" id="9986677at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035673">
        <property type="term" value="F:oligopeptide transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004648">
        <property type="entry name" value="Oligpept_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004813">
        <property type="entry name" value="OPT"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00727">
        <property type="entry name" value="ISP4_OPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00728">
        <property type="entry name" value="OPT_sfam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22601">
        <property type="entry name" value="ISP4 LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03169">
        <property type="entry name" value="OPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0571">Peptide transport</keyword>
    <keyword evidence="6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="75"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="139"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="176"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="232"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="304"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="379"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="433"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="461"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="613"/>
            <end position="631"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="659"/>
            <end position="677"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="689"/>
            <end position="710"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022856"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="OBZ87027.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="746" mass="84150" checksum="2E215376A8A75E97" modified="2016-11-30" version="1">MASKASIHSSHSSNEARNEYRETTFDEKKAASFYDEEVEGVKTATFVDEDSPIEEVRAVVPNTDDPTLPVYTFRMWSLGIIFSCLLSFVNQFFWYRRNAMTLSPLVVQLISFPIGKLMEKVIPKSRFFNPGPFNMKEHVLITAMANCCYSTAYAIDIITIQNLWYDQDMGWGGDILLIWTTQLIGFGMAGVLRPFLVYPSSMIWPANLANISLFRSFHIPDGDWSGTPRFKYFLYCFAAMFVYYWLPGYLFQTLAFFSWACWISPSNKVLSQLTGGAEGLGMLAISFDWSTIVSFLSSPLVVPWWATANVAVGFVLVSWIIAPALYYSNTWNAQKFPIITSALFTKDGLDWDNSIVLNPDKTLNEEAYAAYGPLYMSSFFAFTYGIMFAGVTSIISHTALYHGKEIIAQFKQSRTEDEDIHRKLMRAYPEVPTWWYIAIFIGSFGVSFGVIYGWPEIKLPWWGLILAILIPIIFTLPIGIIQAVTNQQPGLNIITELIIGYALPGHPIANVTFKTYGYISMAQCLTFVSDLKLGHYTKVPPKAMFWVQTVGTVIAGLINLSTAKWLMGSIANICTKDAYPFTCPSAHTFYSASIIWGTIGPGKMFGGNSPYSSVNWFFLIGFFLPIPFWFLSKKYPNSPFKYVHIPLIFNATGMMPPAVPMNFSMWCALGFISMYWLRKYRRNWWIKYNYLTSAAFDSGCAIAALVIWGVSQGTNNYVVEWWGNGSDVSIDHCPLSGQPLITPPEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NE05</accession>
    <name>A0A1C7NE05_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">U3 small nucleolar RNA-associated protein 20</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">utp20</name>
        <name evidence="4" type="ORF">A0J61_04626</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000230">
        <property type="protein sequence ID" value="OBZ87321.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="FunCoup" id="A0A1C7NE05">
        <property type="interactions" value="640"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NE05"/>
    <dbReference type="InParanoid" id="A0A1C7NE05"/>
    <dbReference type="OrthoDB" id="360653at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030686">
        <property type="term" value="C:90S preribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032040">
        <property type="term" value="C:small-subunit processome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052575">
        <property type="entry name" value="SSU_processome_comp_20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057525">
        <property type="entry name" value="UTP20_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046523">
        <property type="entry name" value="UTP20_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011430">
        <property type="entry name" value="UTP20_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17695">
        <property type="entry name" value="SMALL SUBUNIT PROCESSOME COMPONENT 20 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17695:SF11">
        <property type="entry name" value="SMALL SUBUNIT PROCESSOME COMPONENT 20 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20416">
        <property type="entry name" value="UTP20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23099">
        <property type="entry name" value="UTP20_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07539">
        <property type="entry name" value="UTP20_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="U3 small nucleolar RNA-associated protein 20 N-terminal" evidence="1">
        <location>
            <begin position="949"/>
            <end position="1568"/>
        </location>
    </feature>
    <feature type="domain" description="U3 small nucleolar RNA-associated protein 20" evidence="2">
        <location>
            <begin position="1805"/>
            <end position="2023"/>
        </location>
    </feature>
    <feature type="domain" description="U3 small nucleolar RNA-associated protein 20 C-terminal" evidence="3">
        <location>
            <begin position="2372"/>
            <end position="2733"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07539"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF20416"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF23099"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OBZ87321.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="2736" mass="313005" checksum="DA67A57FF1345972" modified="2016-11-30" version="1">MKDNNIPLELNTGQGANRFKYQTFKTRVERIKVDVVRRSKLVDDEPDEHGSFFYESLLEWKDLNMTRNFKDFAKDIQPLVKSLPSIIYHKDTIVDILEKHLKVKGSMALDGLLDLVTKLAKDLEGEFYPYYPRILSCIIPLVYHQDINLLESVFNCIAYLFKFLSRQILPDLDQTFLLLAKLLGEDNQTKPYIRHFTAEAFAFLLRKTRGADLSKAVKCILDTLKAEPSVEFEEGLAMLFFESIKQVDHRLHSRGESIFKELLSQALAEEVSIDDLPTHPVYILLTKTTLLILHHTYRQHFTPIIDIILKEIDLQHSTKKLDEKRFAIQMSLFNMIVTVRKGSRVEDFKPIISCLEQVTKTVFTPKPNTYNNFMYTQVLRSITGVLYHGSLEVIVGGGRVILDTLTKFEDVHLIYGFYLSLAKLRWSSYTQICLPYILKYTSTHFEKHPTETVLFLSKVLAADALVLASGSLSSSLTPEGLLRFPSFGSQKSIVEGMLDIITSSYNWELERDSFNTTDVYSEDRNVSAISLLASVLRVLGKSQVSVDKAFPAIMSLFNSLLDFLQNTTDNSIINSSFVLGHKNFVLESLMGITLQSLVEIATHNAAALTELKKMHDKLVDDILLKHSQNEMVLGSIFLYLELLSLSNADKDKFALVYLEKIYPVLKSNLSSYKRNCRLNTLKILALYDQPLMKPDEDHKLPEVSDIARIALNLEEVEASFKEYRDKVVLIQKLKLITSSKRTPDMLVDFAPLLALGILTINLRPLWDEAKQLLIAFSNVNSEGYWQLLHGELLKFADPKSLVWDGFSKGAVNKLLTMDEAESSNATKTGNISFECPTLNNLLHVENRSWSIMDKERAQNLALLFVESSHQGASHMDFWNYYNLLLLTLKETQSITEAKGRNLVVLFFEFLEHEFISTSEEEDEEENDDFREQKETDTSLQILARSSRIIKNRMANWLSMFSVFKNPRAAYRSQDLYAAFMRIIAMGDAKLQAAALECLFTWKDPNVKPYADNLRNLLDDIKFRDELATFIQNEEQIQIDPAHRNGLMPVVMRVLYGRLIQRSKASSKISKGTRRKVILGGISCCKTEEIRYFIDLALEPFQGILELPGVELDDEDNVSKFEFVAEGKHTVEQIAWRKQTGLLNLLEDTIKQFATHILPFLPDLLKVVLYLINFAHSRKSHEDDMEIDGHDAAQSTKSKEIKSLALKRIVEMFKINGDFNFTPFMPSMFSSFISPRLPNLPSESSQDLSSLTSLFLVWSKKSSYAPYLVDYDNRVLPQIVSTLSIKSINEQVLSALLEILESILDLCEDEMEVDTGSTLKDKLVIPHVDLILNHLKYRLTQSKDDTKFNSGRYSVREIAIAARVAPYTKNGDQAASIVELLLPSLKKPSRIIPEKSKQDILTIWAKFIRIVPGFETGSNLYHHYYVMASSMFATAYSRESRVGLLQVFQAFADINPELVKVNELLVMLNTYSEKRIDQPDYDLMLDALSAIADTHYELFNLHQWLPILHQLTHCMHDSEEMAIRGQATYCMAQYLKATKQKADEDEKRKMIGYVNHVIYPAIKRGLRSRVELVRIEFTSLLNSCVKTFSELPAFEDMTPLLGDGDEEVNFFSNIYHMQIHRRARALSRLADYAEQLKLKVATINNIFIPIISAFFSESDRTVDHNLLNQCTATLSALAKILPWGHYYRLLQTYLSYIKENDEKERTYVRVVIGILDAFHFDIQHIELSDETVKSIMGRQKVRIDYLTNDEIMKQAAKDAGEVIAEDDQGDEHIEEEVETKDKSEKIHDVLVEKVLPDLNNLLNNNKSRKSVIVRVPLALGITKLLCHFPEKSKRINLPGLLTSVCHIIRSRAQDVRDITRETLIKISAFLGHTYFDFIIKELRAALQKGYELHVLGYTVNSLLLDMFPRLSVGDLDYCLPQLVDLLVSDIFGETGQEKDADEMTGKTKEARSRRSPAAFEMISKITEFKNVGLLLIPLKDIMSHTESSRTLRKVEDLLRRIALGLVNNPGFESLELLDFAYGLISENNEEYKAQPKAKVKKTQKELNFEVQMKRVLVEPVDFYRANAYRFVYFGLSLLSSALKKIKFDLSNQEYVTRLRKLVNTVGNTLYSSQSANVVLAARIMCHFITLRLPNISGAVTVSIERCFAIIKSSGNSKTNTVQACLRLLTVCIRDNDKSKLTEAQLTYILNFVRPDMEEIERQGTIFALVRAIISRKFMAPEMYDLMDTVSNIMVTNQSREIREQARSVYFMFLMDYPQGKGRLKTQMSFIIKNLEYVHESGRESIMELLHHIISKFGQDILADYVDAIFLALVMRLINDESAKCREMSATLIKSLFTRISDRLPTIYKLLNKWLDQTSKTNLQRAACQVYGLAIDAFGTQLRTQADALVQRLAAILNASHTLINEQTQQDDDVDDAMEVDIQWEVTYYAINTFAKITKTFPKLVYNQETEPVWRSLQHMLLFPHSWVRSSTTKLYGAYFAGVDPENRVIKDTNAKCIYLDVNTLRSLATDFLEQLKSNYVTQEQADQIVKNLFFVGRCLYHIPNDEDVYGEAEEEIKIDDARDEVIEEEENDQHAQVAVSKIGKSAHKRSLNWLFRKASFDARGAAIRKIKSAMILRSSVFKWFAAMCNLMTSDELPPYLMPVVAPIYRTVNDEQNKADGFEELQQLGNEVLSLLQNKAGPTVYFAVYQRVRQQVLKAREDRKSQEAILAVTNPALAAKRKLDKHHKSQAKKKRTRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NE11</accession>
    <name>A0A1C7NE11_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Urease accessory protein F</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">UREF</name>
        <name evidence="4" type="ORF">A0J61_04659</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the UreF family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000232">
        <property type="protein sequence ID" value="OBZ87298.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NE11"/>
    <dbReference type="FunCoup" id="A0A1C7NE11">
        <property type="interactions" value="10"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NE11"/>
    <dbReference type="InParanoid" id="A0A1C7NE11"/>
    <dbReference type="OrthoDB" id="2550922at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016151">
        <property type="term" value="F:nickel cation binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.4190.10">
        <property type="entry name" value="Urease accessory protein UreF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002639">
        <property type="entry name" value="UreF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038277">
        <property type="entry name" value="UreF_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33620">
        <property type="entry name" value="UREASE ACCESSORY PROTEIN F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33620:SF1">
        <property type="entry name" value="UREASE ACCESSORY PROTEIN F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01730">
        <property type="entry name" value="UreF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF009467">
        <property type="entry name" value="Ureas_acces_UreF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0143">Chaperone</keyword>
    <keyword evidence="1" id="KW-0996">Nickel insertion</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022988"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00046339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OBZ87298.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="245" mass="27456" checksum="5DBFCE1B422C44D2" modified="2016-11-30" version="1">MNGLTDFFSSNETSSWLLYILTDSALPTGGFVASSGLEASWQAGLVDNKNLVDFVTSSAHNYASNTNCFVRAGYESLDQEDPLAELTEADTTCDAVMTANSVAKRASLAQGIAMLTLFLKCFTQEDQKHDINIIKKWKSMIRGEKVDGHFAICYGLVCRYLQVDIENTLHLWLYLFTRTIYSSAVRLNIIGPYEAQKMLLMSRKAIETILKQTKEIGLEDCCQTNPLLDVCQGMHDRLYSRLFNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NE32</accession>
    <name>A0A1C7NE32_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">A0J61_04751</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000239">
        <property type="protein sequence ID" value="OBZ87200.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NE32"/>
    <dbReference type="FunCoup" id="A0A1C7NE32">
        <property type="interactions" value="79"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NE32"/>
    <dbReference type="InParanoid" id="A0A1C7NE32"/>
    <dbReference type="OrthoDB" id="6730379at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791">
        <property type="entry name" value="PERMEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791:SF81">
        <property type="entry name" value="TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_7G01190)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="59"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="95"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="120"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="155"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="188"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="221"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="291"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="327"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="354"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="384"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="413"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="442"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="62"/>
            <end position="471"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OBZ87200.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="501" mass="55557" checksum="45D9A1ED0DCDA770" modified="2016-11-30" version="1">MSHQEEQAQQNYEEKVVLDDVQTIVYDTQDLEKTAVIDSTEMTPELVAAEKSLLRKLDYLYVMPCIAILNFLQFFDKSALNYAAVLGIKEDTHITTAEFGWLGSIFYLGYLVYQVPNVYLLQIFPIGKYVGGLIVVWGVILAVTCEAKNFSQLAALRFLLGFFEAGIYPCCIMLISTMYRRTEQSGRIGCVYICNGLALAVGGLIGYGIGHMANVGGKAAWQWIMIILGCVTVLFGCFCFFLLVDKPKSKFMRLTPEQQKVVDIRQLDNATVVTRAVNYGQILEALKEPRFYCFILASALINLQNGALNTFGAIITSGFGFSGLNSILLTVPNGVTDCIYIAFAIWYNRKYGNTIHLACVMMGISILGLVLLLVIPIAQVKLVGLYMCWSFAAAYVLFLTAIANNVIGYTKKIFYSSAVMVLYTIGNFAGPQMMSASAGPLYLGGMIGFIVADFLAIILLQIARYLMLKTNKERLANPSSEKFDPSLDLTDIQNTNFIYRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NED9</accession>
    <name>A0A1C7NED9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Regulator of cytoskeleton and endocytosis RVS167</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">A0J61_04484</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000220">
        <property type="protein sequence ID" value="OBZ87465.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NED9"/>
    <dbReference type="FunCoup" id="A0A1C7NED9">
        <property type="interactions" value="117"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NED9"/>
    <dbReference type="InParanoid" id="A0A1C7NED9"/>
    <dbReference type="OrthoDB" id="443981at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030479">
        <property type="term" value="C:actin cortical patch"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043332">
        <property type="term" value="C:mating projection tip"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031097">
        <property type="term" value="C:medial cortex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990528">
        <property type="term" value="C:Rvs161p-Rvs167p complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008289">
        <property type="term" value="F:lipid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051666">
        <property type="term" value="P:actin cortical patch localization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006897">
        <property type="term" value="P:endocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097320">
        <property type="term" value="P:plasma membrane tubulation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07599">
        <property type="entry name" value="BAR_Rvs167p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.30.40:FF:000100">
        <property type="entry name" value="SH3 domain-containing YSC84-like protein 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.60">
        <property type="entry name" value="Arfaptin homology (AH) domain/BAR domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.40">
        <property type="entry name" value="SH3 Domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027267">
        <property type="entry name" value="AH/BAR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004148">
        <property type="entry name" value="BAR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046982">
        <property type="entry name" value="BIN3/RVS161-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036028">
        <property type="entry name" value="SH3-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001452">
        <property type="entry name" value="SH3_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47174">
        <property type="entry name" value="BRIDGING INTEGRATOR 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47174:SF2">
        <property type="entry name" value="SH3 DOMAIN SIGNALLING PROTEIN (AFU_ORTHOLOGUE AFUA_5G07670)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03114">
        <property type="entry name" value="BAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00018">
        <property type="entry name" value="SH3_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00452">
        <property type="entry name" value="SH3DOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00721">
        <property type="entry name" value="BAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00326">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103657">
        <property type="entry name" value="BAR/IMD domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50044">
        <property type="entry name" value="SH3-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51021">
        <property type="entry name" value="BAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50002">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0728">SH3 domain</keyword>
    <feature type="domain" description="BAR" evidence="5">
        <location>
            <begin position="15"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="domain" description="SH3" evidence="4">
        <location>
            <begin position="382"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="309"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="317"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="342"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="360"/>
            <end position="370"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51021"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OBZ87465.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="441" mass="50237" checksum="1BB7A94C74744592" modified="2016-11-30" version="1">MRFQGFQKAVSRLPHQIMSKKGEVTKDAEFIQLETRFNETSKIADQLRIEAQTFRDSVSALLTHQSEMANYLAAMYNQQLSTATDEDQVQFSEQSASPGSLQAVNDAEAAMAYCRDEVLPHLDSVDQFVIRPTYELQEIIKTIQKTIVKRNHKLIDYDRHRLALSKLTTKAERSLNDEKTIIKLQSQLDTATQDYEYLNNALKQQLPAFFNLLFQMMQPIFEHLYNLQNTIFGMIYARCHELITANDQQFVTHAMAVLAGYQWRKQQFDAQAEIENTDLLRSGGKAWLTASGATNSSKLTLQERAALKPDEHRPHEPQQITYSQPQQPQLQQKPSYSQPQQNLSYSQPQQSYYDNPPPSYTTQASSASTRAPPPAPPSRGSSTKTYVIALYDYDAQADGDLSFKKDDKIELVERTRDANDWWTGKLRGAVGVFPGNYVTEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NEN6</accession>
    <name>A0A1C7NEN6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Putative aromatic compound monooxygenase YhjG</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">yhjG</name>
        <name evidence="7" type="ORF">A0J61_04373</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000213">
        <property type="protein sequence ID" value="OBZ87572.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NEN6"/>
    <dbReference type="STRING" id="101091.A0A1C7NEN6"/>
    <dbReference type="InParanoid" id="A0A1C7NEN6"/>
    <dbReference type="OrthoDB" id="2690153at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016709">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.2450">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050641">
        <property type="entry name" value="RIFMO-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43004:SF19">
        <property type="entry name" value="BINDING MONOOXYGENASE, PUTATIVE (JCVI)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43004">
        <property type="entry name" value="TRK SYSTEM POTASSIUM UPTAKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00420">
        <property type="entry name" value="RNGMNOXGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="7" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding" evidence="6">
        <location>
            <begin position="5"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="246"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="255"/>
            <end position="265"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OBZ87572.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="608" mass="68235" checksum="CA5254C134C41627" modified="2016-11-30" version="1">MSNEKVDVFVSGAGPVGLFFTYCMAMRGHTVYCVDPKPCPTDQSRAILMTSRTMEVFESQGLAGDILSDAVILWGTRTHKDGVPVGQIEACGNTPYAHNTVIMQSKTEEILYNRIIKNTSCKIHWNNELISYAQDDNKVISIVRDIHTGEKRTIESKYIVGADGTHSAVRKGNPDWTYLGSTINTKFALADFHLKGDGLEDVFSKFNLYLSNSNAFGMVRVNATHEQGEKPIIRVFGNLEAFERKAEDSGASTHGLRDKSEGVPPNKKEIQEWMDRMCAPTKYEIDELIWSSYFRVNERIANGFRRKRAFLVGDSAHCHSPAGGQGLNTGLQDAFNLCWKLSDVLSGVSSDPDKLLDSFSNEREPIAKAVIQDTGNTIEAASSASTWFQAVRTITMKVALKFPFIRHFAFTKLMQLHIRIDPETSGIIGSSDKGLIKAGEFLPHCVGLRKSIIPRHEVPNTIQRYYLRDLFIRTNKYTAIFLGTCPSSISPDLSLLKKFWIDTRQLPIRRIVIQSSWHTRQSSFPSWISEDEKEEAKQSFYTEESFDRADSVSYHVGLYSIATSYFAGKKPYSVVLIVRPDLYVAHAKLVQSENELDTALGFFSSMFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NEW0</accession>
    <name>A0A1C7NEW0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_06095</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000351">
        <property type="protein sequence ID" value="OBZ85864.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NEW0"/>
    <dbReference type="STRING" id="101091.A0A1C7NEW0"/>
    <dbReference type="InParanoid" id="A0A1C7NEW0"/>
    <dbReference type="OrthoDB" id="2216069at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ85864.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="75" mass="8356" checksum="51A1D309BA51F0D6" modified="2016-11-30" version="1">MHWSQNRIFINEAGFNMLIRRNFSHSKTGMPVKAVVPSNRGVTMTIIGAVCKKGIVELTLCKPNVVQKKNNGTNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NEZ8</accession>
    <name>A0A1C7NEZ8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Transmembrane protein 135 N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_04629</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000230">
        <property type="protein sequence ID" value="OBZ87329.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NEZ8"/>
    <dbReference type="InParanoid" id="A0A1C7NEZ8"/>
    <dbReference type="OrthoDB" id="291792at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026749">
        <property type="entry name" value="Tmem135"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031926">
        <property type="entry name" value="TMEM135_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12459:SF6">
        <property type="entry name" value="GB|AAD46013.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12459">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 135-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02466">
        <property type="entry name" value="Tim17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15982">
        <property type="entry name" value="TMEM135_C_rich"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Transmembrane protein 135 N-terminal" evidence="1">
        <location>
            <begin position="265"/>
            <end position="402"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF15982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ87329.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="452" mass="52056" checksum="4EDE37E0C3CBD7FF" modified="2016-11-30" version="1">MSLESEKPRRTTSYQRLVMKLKRNPSERMDPKDWPKPNTPKDIVQHALIGASRAFLLAYGVRGSISFCLYLFRVLRKRAPWSLILEASFKNPDSLRFGAMFGTFALLWKSINNGMRYYRGKDDRLNGLVSGAIAGLSILFEKKERRVDIAQQLLVRSLQAIYNAGKARDIFYFKNGDALLFAVTCAQVLYAYTMHPETLPPDFYSFMVKAARCPKGALLLNEKNVRGVPITPTEALDMISKLRPTTHAVEVVSKIPLDMPAIPCEMLHPWMDGCQMTALERFAKVFKNFLPVYGTLHFVPMLLLRTQHFKKDPVSMLSKTTLATLKSGAFLASFVTLYQYQICMHRQLLKTGLIGRWNSKYIYGWAGFVCAYLSIFLEDKKRRSELALYVLPKALQSFYRIAYSHQWIFKVKHFEVMMTSFAMGVIMSFYQEEADVLSPFVRKIMYQFFQKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NF07</accession>
    <name>A0A1C7NF07_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Copper transport protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">A0J61_04251</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 5">Membrane</location>
            <topology evidence="1 5">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the copper transporter (Ctr) (TC 1.A.56) family. SLC31A subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000204">
        <property type="protein sequence ID" value="OBZ87691.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NF07"/>
    <dbReference type="STRING" id="101091.A0A1C7NF07"/>
    <dbReference type="InParanoid" id="A0A1C7NF07"/>
    <dbReference type="OrthoDB" id="73901at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005375">
        <property type="term" value="F:copper ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007274">
        <property type="entry name" value="Cop_transporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12483:SF27">
        <property type="entry name" value="COPPER TRANSPORT PROTEIN CTR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12483">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 31 COPPER TRANSPORTERS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04145">
        <property type="entry name" value="Ctr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0186">Copper</keyword>
    <keyword evidence="5" id="KW-0187">Copper transport</keyword>
    <keyword evidence="5" id="KW-0406">Ion transport</keyword>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="139"/>
            <end position="165"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU367022"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OBZ87691.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="186" mass="20582" checksum="3F9BC8335D503C67" modified="2016-11-30" version="1">MSHQHTTSSSMDMDSSSMDMGIFHWSSRGDGLWLDSWIPQTEPAYIGACIGLFIISILSRSLPALESYFVIWRASRNSSASIATTSSTELKSNHEKHYDVLEGSFNSAAYPKPLATPSIPSFSWTTDTVRSLLHTLNAFVGYLLMMVVMTGNGGFFLVITLGIFFGEMAFGRYKYLTNTLHADHAC</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NFQ4</accession>
    <name>A0A1C7NFQ4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Reticulon-4-interacting protein 1, mitochondrial</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">rtn4ip1</name>
        <name evidence="2" type="ORF">A0J61_03972</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000184">
        <property type="protein sequence ID" value="OBZ87971.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NFQ4"/>
    <dbReference type="FunCoup" id="A0A1C7NFQ4">
        <property type="interactions" value="375"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NFQ4"/>
    <dbReference type="InParanoid" id="A0A1C7NFQ4"/>
    <dbReference type="OrthoDB" id="201656at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd08267">
        <property type="entry name" value="MDR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="ER"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050700">
        <property type="entry name" value="YIM1/Zinc_Alcohol_DH_Fams"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11695">
        <property type="entry name" value="ALCOHOL DEHYDROGENASE RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11695:SF294">
        <property type="entry name" value="RETICULON-4-INTERACTING PROTEIN 1, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13602">
        <property type="entry name" value="ADH_zinc_N_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Enoyl reductase (ER)" evidence="1">
        <location>
            <begin position="11"/>
            <end position="333"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ87971.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="335" mass="36637" checksum="6A64F39C360A163F" modified="2016-11-30" version="1">MRALELVQFGSPVDCFSYNEHVPTPSIQSPYQLLVRVKAAGTNPVDTKIASGDFHLGSRLPYIIGADFAGVVEEVGDQVDGFKLGDAVFGSLHMPFSWCGSYAEYTLIDLRHDSVAKKPDSLSFEQAASAGIAILTAYQGIVNHSRTSYPSRRILIVGASGGVGAYGVQLAKALNHKVIGICSGKNVPFVKQMGADQVVAYTDTDQFTQFRMDHQGYFDLVFDCVGGEDYYTMLDPLLNDQGQYVSAVTPGTTHSTLSMASKLVYKHCFATHAYSMILSLPHHDFRSRIAPLFETGALRGMVQDEKENVMSLREGYKAHLKLATHRTVGKIVLQI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NG61</accession>
    <name>A0A1C7NG61_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Solute carrier family 2, facilitated glucose transporter member 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">SLC2A1_0</name>
        <name evidence="9" type="ORF">A0J61_03944</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000182">
        <property type="protein sequence ID" value="OBZ88008.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NG61"/>
    <dbReference type="InParanoid" id="A0A1C7NG61"/>
    <dbReference type="OrthoDB" id="4540492at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015149">
        <property type="term" value="F:hexose transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045263">
        <property type="entry name" value="GLUT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23503:SF8">
        <property type="entry name" value="FACILITATED GLUCOSE TRANSPORTER PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23503">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00171">
        <property type="entry name" value="SUGRTRNSPORT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00217">
        <property type="entry name" value="SUGAR_TRANSPORT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0762">Sugar transport</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="52"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="86"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="109"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="142"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="170"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="281"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="319"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="8">
        <location>
            <begin position="1"/>
            <end position="352"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OBZ88008.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="352" mass="38380" checksum="7E345986DA60F7CE" modified="2016-11-30" version="1">MVASLGSFNSGFNTSALNIPGNAVRNCPNVPAGEVTYYSNSSLPQCIPMSDWIWGVATGMFAVGGLVGAMASGYLSNKFGRRDSMILMNVNFFIGAALLSTATTSGQFALGRIFVGAGSGFMTCVIGIYVSEISPPKYRGALTSLLQLFTTLGILIIECISIGLNSAIGWRIVVIITVVPTILQMLLLPFCARSPRWLVSQNRIDEARVQFLRLRNGDIESEFTDMLLGITKGVEEKKHADSDMDSASAFDNNAINKTEKTSAAFESEAQLNLIQIMSIPVLAWLCIKIFIFHALSQLTGINAIMYYSTNIFEASFGDNAQYVTVGXFSCASFIRFFVLKGFQRQKLIAYYI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NG99</accession>
    <name>A0A1C7NG99_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">separase</fullName>
            <ecNumber evidence="2">3.4.22.49</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">bimB</name>
        <name evidence="7" type="ORF">A0J61_03876</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>All bonds known to be hydrolyzed by this endopeptidase have arginine in P1 and an acidic residue in P4. P6 is often occupied by an acidic residue or by a hydroxy-amino-acid residue, the phosphorylation of which enhances cleavage.</text>
            <dbReference type="EC" id="3.4.22.49"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.22.49" evidence="2"/>
    <dbReference type="EMBL" id="LUGH01000177">
        <property type="protein sequence ID" value="OBZ88065.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NG99"/>
    <dbReference type="InParanoid" id="A0A1C7NG99"/>
    <dbReference type="OrthoDB" id="10255632at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072686">
        <property type="term" value="C:mitotic spindle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044732">
        <property type="term" value="C:mitotic spindle pole body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004197">
        <property type="term" value="F:cysteine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051307">
        <property type="term" value="P:meiotic chromosome separation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005314">
        <property type="entry name" value="Peptidase_C50"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030397">
        <property type="entry name" value="SEPARIN_core_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12792">
        <property type="entry name" value="EXTRA SPINDLE POLES 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12792:SF0">
        <property type="entry name" value="SEPARIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03568">
        <property type="entry name" value="Separin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51700">
        <property type="entry name" value="SEPARIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0159">Chromosome partition</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase C50" evidence="6">
        <location>
            <begin position="1828"/>
            <end position="1923"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1094"/>
            <end position="1113"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000451"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012489"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51700"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OBZ88065.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="2010" mass="229650" checksum="7C922555F2B70856" modified="2016-11-30" version="1">MSDLASRLLLQLKDYGKCNDELAVSVKKAILEPFQVDLNRPESARKPPTTSKFKQMATQLAPIAMRIVNQNIDGLLNLKRTIKETSHYTIAVNCLLDTSFYALTALRHMNTYTALKPLDIEKATSNLICKMVELGEYQRALDEMRKFRVLLAGIAKVQLNPKSTPVIVVDNRQKGVLTESNVLNVGSLKNTNSDIPESVIKNQWENDMLKEYQDLFQFPLDSTINDRTMILLVLAYQMNTIRSWCEIRDGALVKYVPYFLERPGNFLHWCKHLLQLDQTTARKQLDTLYKLLYKATNRLPISEENAFYSYHIQVFSLKALLLAGSTSLQSIMDRLVVIGTTYEKATKQVSYSYVQQCCHEFLELIQPNIEKLSVMDSYFVLCEYYAYISRKAKSYKGAFYAYKFMVRPIRHLLDGEHGNYYYAAYAANAKLALGAVQMDKIVLDNNFADISTTLNESIACLRIVSHAVSQSSHHDSHSEQALYNLSKSVNTFLQSAKRLHQHIEKTEGSSLSDKWHGLVVYLIRVLQQCSETLPANFSLAKDSPAKRVATQSDMVLTFVDIMILLSRLQLDANNPDSHHTAYEYLSTAEQMCIEKKCTDGYRWLSGAYYTIGTTIIKTEEYGAAIYPLRKSSSLLEKDVERANTEEGKLQLCKRYEILGLCCHKHKDYEDSVKAYRLALKRVPLSTIKQFTSQVESTAISTIIEREILIPKLMDRFLRAVVVDPDMTSIHFASEYITTTGFSALEQAALYECELKVWYGISLKMNVYKYQKMLVDKLLQIYQASKHPIRRARVLLSQVRIERSKPSVNQNESIQTALACAQEAFELLKVQDYGKDSSLLAYRRYYVALSMSWMVICERELGQASSSNSFEFSLQQWSVLLKKITPIYYAKPSVKQDIQQVFDEIDDVDQFYDHIRMLADLFAVVGEPVFRIRALRILLKLNNGFRDAQIDHISDSITYLCTIGKIFCELGYTGKASVEFNYAKKLISSYKCSNLADIYYRVYYAHYLTYIDDFETSKETFEEARDIWKNTPVVSSKDSSATVKSYTSRCMLLADVYTTQSSILSHTDSLDRAIDAATAALSLLNKCIKVIQKSDQDRQPSASKQLEDPFMPARDQQEDSKVVYRESQWILAQKIGQLLQRLAQLYMDKGSWHEAHYFVKQGPLLAEKVKSNSLYFESYLCTSAYYLKYGDLDKSQQALEDAAELQLTGEYHGLDEIRIKLWMANLALANAFPNIAMDAYQEAEGLLDQLLLPAYISGLEQLVETKKTIDESADLSDAYSCLPLQKIKSVILLKKATVFFEQGQPEVALDLLEKMEESGAMIADEIEFSACLSRFKLAITHKALEPELGKFYHESTVLPAMKTQAARGTMMKKSTINQELLMVRDDLTNVLERMLDARLVAWAREPTPVIQFLSNASGFTMFLKNQLYGQSRALATNYALLEAYYTSMANGIHMRREMQNSLRVKINPSCLTLPSDTDWPLSEEERDQQQQHTRLPRWLQAHLNTLVELYREENDLSDKEFQDKFINILPSHWTICSLTMDIERKDLYIAQLRSHEEPFVVKIPLNRTTHRKDNCYPPVMQYEDAASELKDIIEASDDTIHNGASCVQPAQVEAWWNARKDLDNRLKVLLDNIEDQWLSGFRGLLAGRCQEHKEELRKYQKALSETVFRSVHQASGTKKQTELSLPFCRMVLRLGRQPLVRDLEDIVWFILSCYEAQDALIDYSKLNLKKLMDDIRLLGSRYHEKCNMTGINTTKNIPNDHLILILDKHLQMLPLESMPLLRSQSVSRLPCLSFLRDRVLYARAHHGRAAFDDFGAIITDQWSDIAISQKNAFYVLNPGGDLKDTQKEFEPFFKSVRGWDGVIQKKPLELQLKEALQTRDLYMYFGHSAGQAFMRGTTVRQLPVCAVSLLMGCSSGLIETQGEFDPYGYVLNYLLAGSPAVVANLWDVTDRSIDRLTKHMLSTWGMLKQTAQNKSIVQAVAESRSKCKLSYLIGAAPVVYGIPVYLEPYST</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NGE4</accession>
    <name>A0A1C7NGE4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">PHD-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">A0J61_03739</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000167">
        <property type="protein sequence ID" value="OBZ88211.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NGE4"/>
    <dbReference type="STRING" id="101091.A0A1C7NGE4"/>
    <dbReference type="InParanoid" id="A0A1C7NGE4"/>
    <dbReference type="OrthoDB" id="5863171at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.50.10">
        <property type="entry name" value="Erythroid Transcription Factor GATA-1, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013088">
        <property type="entry name" value="Znf_NHR/GATA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001965">
        <property type="entry name" value="Znf_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019787">
        <property type="entry name" value="Znf_PHD-finger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00628">
        <property type="entry name" value="PHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00249">
        <property type="entry name" value="PHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50016">
        <property type="entry name" value="ZF_PHD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="PHD-type" evidence="6">
        <location>
            <begin position="376"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="108"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="197"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="250"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="111"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="260"/>
            <end position="271"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OBZ88211.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="457" mass="51582" checksum="BAAF55896F4472EC" modified="2016-11-30" version="1">MTDIQPDIQLTVLSQSFPYNLWDAVLLDQTTLAKPIGDSSPDTYHECNPAALPIGGPRIAISQLILGPTLDFTRPFMLLSGNTLIKDDVFLASDSPLYPTSSFHLDQDDNASLSSHSTSSSQQLATSPHLSPVTSPTNFLYNHEPLFDGGIIEPTHESDDDILSVSTESTKQPSSSENDLDWYKLLDAFHEDVACDNIPSPRSEPTVFDEPNDDSEDGFSILFHNSAKNLKRARSQTPASELSFLDLDEFPYKRPTTNPRQKRRKKHTQALKKKEDKKKPAPSFTASRCQLIEPIANQKDNKTVFQHLTETSIDWCRYCGTTEGVNWRPGPWGKRTLCNKHGCDYKGYGLASRLPRLDLSAFSNERLQDRIRPVVQHFCIVCQSPEETEKDNQLILCEGGCSRAYHQKCHAPMITVNPTMDAVRWYCSPLCKENRKRNKVVVELPRKHMPLMHLLKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NGK0</accession>
    <name>A0A1C7NGK0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Zinc phosphodiesterase ELAC protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">ELAC1</name>
        <name evidence="9" type="ORF">A0J61_03833</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="2">Homodimer.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000174">
        <property type="protein sequence ID" value="OBZ88110.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NGK0"/>
    <dbReference type="STRING" id="101091.A0A1C7NGK0"/>
    <dbReference type="InParanoid" id="A0A1C7NGK0"/>
    <dbReference type="OrthoDB" id="527344at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042781">
        <property type="term" value="F:3'-tRNA processing endoribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd07717">
        <property type="entry name" value="RNaseZ_ZiPD-like_MBL-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="entry name" value="Ribonuclease Z/Hydroxyacylglutathione hydrolase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01818">
        <property type="entry name" value="RNase_Z_BN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013471">
        <property type="entry name" value="RNase_Z/BN"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46018">
        <property type="entry name" value="ZINC PHOSPHODIESTERASE ELAC PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46018:SF2">
        <property type="entry name" value="ZINC PHOSPHODIESTERASE ELAC PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23023">
        <property type="entry name" value="Anti-Pycsar_Apyc1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="Metallo-hydrolase/oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0540">Nuclease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0819">tRNA processing</keyword>
    <keyword evidence="8" id="KW-0862">Zinc</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OBZ88110.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="377" mass="42559" checksum="F0E5B8035EA74A29" modified="2016-11-30" version="1">MVVSMDITFLGTGSAQPSATRNHQAMALRVDGDIWLFDCGEATQHQFQKSQLKMGKITRIFITHMHGDHCFGLGPLLCSMTDNLNPNQEDKKDEKPIEIYGPSPLRAWIRTTLKSTYSNLGRTYRVHELLHEHDPVDLHQDRHPNELEGQNVLIDGNKFDLPCFDGDYRVQAAPIEHSIPSLGYVIHEAEIPGKLDSLIPLIKKNAQALKAQGIKNPMSLLGQVQRTQKPYDLPDGDKLIPPPKRPGRQLVILGDTKDPSSLIPLVHRPTLLVHEATNALTRLDLDAKDPMTLEQVEERTKNHGHSTPQMAAHFAKKISCSKLILTHFSARYRGDEDPEAIEVMEEIRKLAVDVFDKRDQDVFCARDLWSFDIKLES</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NGK8</accession>
    <name>A0A1C7NGK8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_03709</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000165">
        <property type="protein sequence ID" value="OBZ88233.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NGK8"/>
    <dbReference type="InParanoid" id="A0A1C7NGK8"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ88233.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="66" mass="7431" checksum="99F55022B8806010" modified="2016-11-30" version="1">MLAIHCQFAIEPTQIKIELSSNGEYDKEWVKALSSMATHGQCAVDIIFRPNHLISYELLHSVTAET</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NHB3</accession>
    <name>A0A1C7NHB3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Polyamine oxidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">PAO_0</name>
        <name evidence="3" type="ORF">A0J61_05195</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000274">
        <property type="protein sequence ID" value="OBZ86754.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NHB3"/>
    <dbReference type="STRING" id="101091.A0A1C7NHB3"/>
    <dbReference type="InParanoid" id="A0A1C7NHB3"/>
    <dbReference type="OrthoDB" id="5046242at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006598">
        <property type="term" value="P:polyamine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.660.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002937">
        <property type="entry name" value="Amino_oxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050281">
        <property type="entry name" value="Flavin_monoamine_oxidase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10742:SF313">
        <property type="entry name" value="AMINE OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10742">
        <property type="entry name" value="FLAVIN MONOAMINE OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01593">
        <property type="entry name" value="Amino_oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008889702" evidence="1">
        <location>
            <begin position="21"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="domain" description="Amine oxidase" evidence="2">
        <location>
            <begin position="34"/>
            <end position="464"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ86754.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="499" mass="56616" checksum="AF60E1D3F043B0F9" modified="2016-11-30" version="1">MRSLFLTSSIVLLYGMLAQAKEYHTKVVILGGGVSGISAALNLTANNISNFMMVEARDILGGRAQDVPFADVNVEMGCNWVQGLGTNPINQLAIKYNLRTADTDGDNVVFYDEKGKVNATERYKDMNDAYTAMSEIADKRVKNDQVDISGRVGLSLAGWYPKNSVDDAIEYYVWDWEMGENPELSSTLFTVVNDYWTYGNKAFGPNSDGDHMVIDPRGFKHIFLQEAKRVFKHNDPRLLLNTTVTKVAYNGKGVTISTRQGDTIHADYAITTFSLGVLQHRDVEWEPPLPEWKLEGLYGFHMATYTKIFLNFPSKFWDDQQFIVYADPDQRGYYAAWQNLNAPGFLPNNSHSHIFFATVTQDMSYRVEAMEDDEVKEEIMQVLRRMYGDDIPEPTDFVFPRWHSNPLFRGSYSNWPIGEMDEHHANMKAPVKNRVFFAGEAMSEEYYGFLQGAWLSGAETAVHVAQCVKSTCPEAKFYPEIKKAKLEASIVRRSILENN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NHV6</accession>
    <name>A0A1C7NHV6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">acetyl-CoA C-acetyltransferase</fullName>
            <ecNumber evidence="2">2.3.1.9</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">erg10</name>
        <name evidence="10" type="ORF">A0J61_03836</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="5">Metabolic intermediate biosynthesis; (R)-mevalonate biosynthesis; (R)-mevalonate from acetyl-CoA: step 1/3.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the thiolase-like superfamily. Thiolase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.9" evidence="2"/>
    <dbReference type="EMBL" id="LUGH01000174">
        <property type="protein sequence ID" value="OBZ88116.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NHV6"/>
    <dbReference type="FunCoup" id="A0A1C7NHV6">
        <property type="interactions" value="271"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NHV6"/>
    <dbReference type="InParanoid" id="A0A1C7NHV6"/>
    <dbReference type="OrthoDB" id="5404651at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003985">
        <property type="term" value="F:acetyl-CoA C-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006696">
        <property type="term" value="P:ergosterol biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006635">
        <property type="term" value="P:fatty acid beta-oxidation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00751">
        <property type="entry name" value="thiolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.47.10:FF:000007">
        <property type="entry name" value="acetyl-CoA acetyltransferase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002155">
        <property type="entry name" value="Thiolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020615">
        <property type="entry name" value="Thiolase_acyl_enz_int_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020610">
        <property type="entry name" value="Thiolase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020617">
        <property type="entry name" value="Thiolase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020613">
        <property type="entry name" value="Thiolase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020616">
        <property type="entry name" value="Thiolase_N"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01930">
        <property type="entry name" value="AcCoA-C-Actrans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18919:SF165">
        <property type="entry name" value="ACETYL-COA ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18919">
        <property type="entry name" value="ACETYL-COA C-ACYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02803">
        <property type="entry name" value="Thiolase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00108">
        <property type="entry name" value="Thiolase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000429">
        <property type="entry name" value="Ac-CoA_Ac_transf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="Thiolase-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00098">
        <property type="entry name" value="THIOLASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00737">
        <property type="entry name" value="THIOLASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00099">
        <property type="entry name" value="THIOLASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7 10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Thiolase N-terminal" evidence="8">
        <location>
            <begin position="6"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="domain" description="Thiolase C-terminal" evidence="9">
        <location>
            <begin position="275"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="active site" description="Acyl-thioester intermediate" evidence="6">
        <location>
            <position position="90"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="6">
        <location>
            <position position="352"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="6">
        <location>
            <position position="382"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00037924"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR000429-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF02803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OBZ88116.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="396" mass="41368" checksum="DAF2C76887916D1A" modified="2016-11-30" version="1">MTQREVYIAAAVRTPLGGFNGSLASLPATKLGSIAIEAAVKKVNLPAEAVEEVVFGCVLTANLGQNPARQAALGAGLADTTVATTVNKVCASGMKAVILAAQTIMLGNAEVVVAGGMESMSNTPYYLPKQRFGSTYGNTEVVDGIVKDGLTDVYNNYLMGIAAEECAAEYEITRDQQDDFAIESYKRAQAAFAAGHYKEEIVPVTVSGGRGKPDRVIEQDDEVAKLNEEKLRAVRPAFQPKNGTVTAPNSSPLSDGASALILVSKEAAEKYNLPLIAKIKGWGEAAQAPARFTTSPALAIPKAIKHASLTAEEIEFYEINEAFSVVACANKKILNLPDNKVNVWGGAVAMGHPLGCSGARIITTLSSVLKGHNAKYGVAGVCNGGGGASAIVIERL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NI05</accession>
    <name>A0A1C7NI05_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Histone-lysine N-methyltransferase ASH1L</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">Ash1l</name>
        <name evidence="13" type="ORF">A0J61_03173</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Chromosome</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000132">
        <property type="protein sequence ID" value="OBZ88772.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NI05"/>
    <dbReference type="STRING" id="101091.A0A1C7NI05"/>
    <dbReference type="InParanoid" id="A0A1C7NI05"/>
    <dbReference type="OrthoDB" id="422362at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016593">
        <property type="term" value="C:Cdc73/Paf1 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005694">
        <property type="term" value="C:chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042054">
        <property type="term" value="F:histone methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006368">
        <property type="term" value="P:transcription elongation by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00202">
        <property type="entry name" value="ZnF_GATA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.50.10">
        <property type="entry name" value="Erythroid Transcription Factor GATA-1, subunit A"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.270.10">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006560">
        <property type="entry name" value="AWS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007149">
        <property type="entry name" value="Leo1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050777">
        <property type="entry name" value="SET2_Histone-Lys_MeTrsfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001214">
        <property type="entry name" value="SET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046341">
        <property type="entry name" value="SET_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000679">
        <property type="entry name" value="Znf_GATA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013088">
        <property type="entry name" value="Znf_NHR/GATA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22884">
        <property type="entry name" value="SET DOMAIN PROTEINS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17907">
        <property type="entry name" value="AWS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00320">
        <property type="entry name" value="GATA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04004">
        <property type="entry name" value="Leo1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00856">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00570">
        <property type="entry name" value="AWS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00317">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00401">
        <property type="entry name" value="ZnF_GATA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57716">
        <property type="entry name" value="Glucocorticoid receptor-like (DNA-binding domain)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82199">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51215">
        <property type="entry name" value="AWS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00344">
        <property type="entry name" value="GATA_ZN_FINGER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50114">
        <property type="entry name" value="GATA_ZN_FINGER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50280">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0158">Chromosome</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 13" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="5 13" id="KW-0808">Transferase</keyword>
    <keyword evidence="8" id="KW-0862">Zinc</keyword>
    <keyword evidence="8" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="GATA-type" evidence="10">
        <location>
            <begin position="82"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="domain" description="GATA-type" evidence="10">
        <location>
            <begin position="190"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="domain" description="AWS" evidence="12">
        <location>
            <begin position="343"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="domain" description="SET" evidence="11">
        <location>
            <begin position="397"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="35"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="118"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="221"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="537"/>
            <end position="634"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="858"/>
            <end position="950"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="537"/>
            <end position="546"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="599"/>
            <end position="611"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="612"/>
            <end position="623"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="873"/>
            <end position="888"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="902"/>
            <end position="913"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="914"/>
            <end position="933"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00094"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50114"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51215"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="OBZ88772.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="950" mass="108935" checksum="F947B14ED7DB068E" modified="2016-11-30" version="1">MADILSKENIPPPSIDNKIISTCSIMDNHHTMIHTDDHHISSSSSSSSSEEPSTPIPVTIENAPSLNDLDKVPVLEEGVRWCQRCGTIETPRWRYGPGGPLTLCNACHLRWKTQGRPASGYSSTTYPPPHYSPTLKRKRTSKSNATGLKRVKREDEDQDLKLTKAILKKPKITSSPSPPVIEPEIIPGTCTSCHCTTTPLWRKGPLGPKTLCNACGLKWAKETDKPPSSRSSPPKPVVKATTTHKKSPNHSLLHHQKQFIKHGLYADEVRLEKPKPKSRFVFELPVHQGAFMLSKQADFELPADILQERELGLIKGLRSDRQPSFTRIRSNIFVERKPSTTSADPVVCHCQKPANQEEAGCGEDCINRMLFYECDPKSCPCGDQCSNQRFQRKERKKELQIFQTENRGWGLRTLVDIKKDELVIEYRGEIISHQLCEERMCTIYVNEKNFYFLDYCNGEVIDACYKGTEARFINHSCDPNCHIEKWSLRGESHFGVFASTDIKANSELFYDYNFSTFNGSVESQQPCYCGTVKYEENQSGSDRDFGDLFGSEDEASDIDDGRSQSSHEAQPPPAQQTNNDLDNLFGSGESESESEQNDDQQQTIKSRSSPMSEDEKEMEDNDYEGPSSQKQRVEVSLEMPQLSIPYSDNNQYYLAKLPRFLDIETTPFVPEDFEIRVEEGLTEAQEQEAIREQVESTIRWRRLNENGVETMRSNAHLVEWEDGKISLMLGDECFDVSSKPVGTHEHAYLLAHQTDSGALESQTEFTHHMTFRPSGLKSDTHRHLTAQIADKQIKKNKTKMFFTEKDPELMKQELETQENERLKAQKKLELQRRKADIRYSDSSLRRNLNDFGDYEAASDYTRTQSTSRAQDRYEDDFVVDDEEYDEEEERSRENRLAQAKRVGMDKYKRPRYSDDDDEEEEEEDYGNDDEEEELVVRRHKRNRVFSDEDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NI14</accession>
    <name>A0A1C7NI14_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">1-phosphatidylinositol 4-kinase</fullName>
            <ecNumber evidence="2">2.7.1.67</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">pik1_0</name>
        <name evidence="8" type="ORF">A0J61_03163</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol 4-phosphate) + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:19877"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57880"/>
            <dbReference type="ChEBI" id="CHEBI:58178"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.67"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.67" evidence="2"/>
    <dbReference type="EMBL" id="LUGH01000132">
        <property type="protein sequence ID" value="OBZ88782.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NI14"/>
    <dbReference type="FunCoup" id="A0A1C7NI14">
        <property type="interactions" value="782"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NI14"/>
    <dbReference type="InParanoid" id="A0A1C7NI14"/>
    <dbReference type="OrthoDB" id="10264149at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004430">
        <property type="term" value="F:1-phosphatidylinositol 4-kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046854">
        <property type="term" value="P:phosphatidylinositol phosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048015">
        <property type="term" value="P:phosphatidylinositol-mediated signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05168">
        <property type="entry name" value="PI4Kc_III_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1070.11:FF:000016">
        <property type="entry name" value="PIK1p Phosphatidylinositol 4-kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.1260">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1070.11">
        <property type="entry name" value="Phosphatidylinositol 3-/4-kinase, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1010.10">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021601">
        <property type="entry name" value="Phosphatidylino_kinase_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015433">
        <property type="entry name" value="PI3/4_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000403">
        <property type="entry name" value="PI3/4_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036940">
        <property type="entry name" value="PI3/4_kinase_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018936">
        <property type="entry name" value="PI3/4_kinase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001263">
        <property type="entry name" value="PI3K_accessory_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057754">
        <property type="entry name" value="PI4-kinase_beta/PIK1_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049160">
        <property type="entry name" value="PI4KB-PIK1_PIK"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10048:SF22">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL 4-KINASE BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10048">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00454">
        <property type="entry name" value="PI3_PI4_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21245">
        <property type="entry name" value="PI4KB-PIK1_PIK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11522">
        <property type="entry name" value="Pik1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00146">
        <property type="entry name" value="PI3Kc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00915">
        <property type="entry name" value="PI3_4_KINASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00916">
        <property type="entry name" value="PI3_4_KINASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50290">
        <property type="entry name" value="PI3_4_KINASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51545">
        <property type="entry name" value="PIK_HELICAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 8" id="KW-0418">Kinase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PIK helical" evidence="7">
        <location>
            <begin position="1"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="domain" description="PI3K/PI4K catalytic" evidence="6">
        <location>
            <begin position="695"/>
            <end position="969"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="216"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="314"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="570"/>
            <end position="594"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="220"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="318"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="570"/>
            <end position="590"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001686"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51545"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OBZ88782.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="984" mass="110187" checksum="74F177D6C62A8C26" modified="2016-11-30" version="1">MSNALLLRLFTSEYFNAWIAISYIFRHPDNVGIQHYLCTQLRKFPIAEIEFFLPQLMHLLITRPTESVALELYIIDACEKSTHIAVMCLWYLQAYLSDLSANPNHPSFQLCKRVFNRCQTIIFADDDTKEENEEDQKEEWSHSSLYAARLDRTQRVRENALPALVGMGALLAGIGQPCVTRPVGSIAIAQGRKPSFQTFDSSNLAMNRSSTYEHDHPIARSQSQPHLSISTTKRARPHSLSSALSSVLVDKDHDFSVSLEDLHRGKAFSISRYLKQAQQKIQHTVHSTLTTTHNNNVPLELMNSDGISSVNMKAMAQSSVPSSQDVPSTPTTPTTLVSPSRSFSSDDAFGQSPPKGPVSFDPRLDEEDLVQNSSDSDDDEVYALAKLSLGDRRQLLRSNYFRSEMQFLLALVDIATRLVIVPKPARLSALHAELTLLNHNLPAEICMPLWCPATVDRPYHHRIVRISPTDAVVLNSAERAPYLLMIEVLDDELSLENGFKSSLSKIKKSTKNNHLKRLSIAKQKEALEDAIVDLGDLGSPISTRNSLEIAPSSSTATTATAVSYNKSRDSIDSRVLHDEPEQNKTIEKEPSSSFDDDAFAEKMKTAAILLAQLQLEPQPIVKTSTEGIRQKIIAEMMALEDDRMEKMALEGVAKGIGGGGGEGAGSAKKLDDEQRVAMVVNKEDPSAAVFSEDWETKKERIRTASPYGHLPNWRLISVIVKNGADLRQEQFAIQLIREMQKIWQDTKVNVWVQYIRVLVTSDDSGLIETVKNSISIHSIKKEAYTRKWNEQGAVFSLKDYFVRRWGSSESSRFKKAQDAFMRSLAGYSVASYLLQIKDRHNGNLLLDDMGHIIHIDFGFILSNSPGSVGFEMAPFKLPQEYVDILGGVDSPKFNEYKALTKAAFLAVRKHSDNILLLTEMMSKDSKLPCFQNGPATVSALRDRFQLQMTETQVEAHVEKLIVSSCCNVFTRLYDTYQYYSQGIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NJB2</accession>
    <name>A0A1C7NJB2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Probable electron transfer flavoprotein subunit alpha</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">ETFA</name>
        <name evidence="12" type="ORF">A0J61_02747</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8 9">The electron transfer flavoprotein serves as a specific electron acceptor for several dehydrogenases, including five acyl-CoA dehydrogenases, glutaryl-CoA and sarcosine dehydrogenase. It transfers the electrons to the main mitochondrial respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase).</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="9 10">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
        <text evidence="9 10">Binds 1 FAD per dimer.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3 9">Heterodimer of an alpha and a beta subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Mitochondrion matrix</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the ETF alpha-subunit/FixB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000107">
        <property type="protein sequence ID" value="OBZ89217.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NJB2"/>
    <dbReference type="FunCoup" id="A0A1C7NJB2">
        <property type="interactions" value="316"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NJB2"/>
    <dbReference type="InParanoid" id="A0A1C7NJB2"/>
    <dbReference type="OrthoDB" id="1715808at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033539">
        <property type="term" value="P:fatty acid beta-oxidation using acyl-CoA dehydrogenase"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01715">
        <property type="entry name" value="ETF_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.620:FF:000041">
        <property type="entry name" value="Electron transfer flavoprotein alpha subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1220:FF:000001">
        <property type="entry name" value="Electron transfer flavoprotein, alpha subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1220">
        <property type="entry name" value="TPP-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029035">
        <property type="entry name" value="DHS-like_NAD/FAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014730">
        <property type="entry name" value="ETF_a/b_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001308">
        <property type="entry name" value="ETF_a/FixB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033947">
        <property type="entry name" value="ETF_alpha_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014731">
        <property type="entry name" value="ETF_asu_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018206">
        <property type="entry name" value="ETF_asu_C_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43153">
        <property type="entry name" value="ELECTRON TRANSFER FLAVOPROTEIN ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43153:SF1">
        <property type="entry name" value="ELECTRON TRANSFER FLAVOPROTEIN SUBUNIT ALPHA, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01012">
        <property type="entry name" value="ETF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00766">
        <property type="entry name" value="ETF_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000089">
        <property type="entry name" value="Electra_flavoP_a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00893">
        <property type="entry name" value="ETF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52402">
        <property type="entry name" value="Adenine nucleotide alpha hydrolases-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52467">
        <property type="entry name" value="DHS-like NAD/FAD-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00696">
        <property type="entry name" value="ETF_ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 9" id="KW-0249">Electron transport</keyword>
    <keyword evidence="6 9 10" id="KW-0274">FAD</keyword>
    <keyword evidence="5 9" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="9" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Electron transfer flavoprotein alpha/beta-subunit N-terminal" evidence="11">
        <location>
            <begin position="30"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="231"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="256"/>
            <end position="257"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="270"/>
            <end position="274"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="287"/>
            <end position="294"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="308"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004305"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005817"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011355"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00025416"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRNR" id="PIRNR000089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR000089-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM00893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="OBZ89217.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="339" mass="35219" checksum="B564F7323E6B8813" modified="2016-11-30" version="1">MFFTATSRIALQARATLAQRFYATGAGANTLLYVEHKDGAISGATLNALTAANKLGGSISALVAGDAPESVVQQVAKLNGVSKVLTAKDAAYTNALPEDIAPLLVAAQKQFGFTHLFTGHTASGKNIFPRAAALLDVAAVSDIVGIEGEDTFVRPIYAGNAIATVKSNDNVKVVTVRGTAFEAAGTKDDSAAEEAAPAADKPALTQWISEEIQKSDRPDLNTAKRVISGGRGMKNGENFKMLYDLADKLGAAVGASRAAVDAGFVDNSLQVGQTGKIIAPELYIAVGISGAIQHLAGMKDSKTIVAINKDADAPIFQVADYGLVDDLFKAIPELTEKVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NK36</accession>
    <name>A0A1C7NK36_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Protein MSP1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">MSP1</name>
        <name evidence="8" type="ORF">A0J61_03097</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion outer membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000127">
        <property type="protein sequence ID" value="OBZ88856.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NK36"/>
    <dbReference type="InParanoid" id="A0A1C7NK36"/>
    <dbReference type="OrthoDB" id="39734at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005741">
        <property type="term" value="C:mitochondrial outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041569">
        <property type="entry name" value="AAA_lid_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003960">
        <property type="entry name" value="ATPase_AAA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051701">
        <property type="entry name" value="Mito_OM_Translocase_MSP1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45644:SF56">
        <property type="entry name" value="AAA ATPASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G12920)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45644">
        <property type="entry name" value="AAA ATPASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G12920)-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17862">
        <property type="entry name" value="AAA_lid_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00674">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="3" id="KW-1000">Mitochondrion outer membrane</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="7">
        <location>
            <begin position="589"/>
            <end position="726"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="183"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="192"/>
            <end position="205"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004572"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OBZ88856.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="831" mass="93691" checksum="F057E1FEFF8FE022" modified="2016-11-30" version="1">MSFVARLNRLPIRQTQKWLQNSMINRNASSSTKLPKPNTLGRQKSIKLRRNRVPATLSDSFLRTNYMQPTSLSSLPDKYASFIPDYVLKELEYSVRSGLSPKGTIATFNHTDHIAISIPNTGACYLQDHIVRQLSAKANADLFVLDPQDFVSIAQQNFSRDVAAVLPILSSVDPESNVILALSQSDIDDPYENTKEDQDDTERGNSDGAYEIFVKSNSEKENDGNNLPEDDQDENIEDTLEDDRLKINVHPSEPSTNRVINMEGVEIDLDDIYGNGSQDQKAQQMHKISKSTLNQVSSRYTSMFKKLLSNGSIPKSENKEKGTVIYLRDYGSMQDAFTRIMLKSLLLAVEDLKQRGHRLMIVASYCLKPDLDEILVPAIPNLRYISVLPSLKNKQHMEQWKTLMKQDEISRAAEINAKQVLAVYRQKNILETQSLQEQEELLSSLIFSLKNDSMSKSVWTPKEVDRRVTTAIGHALESSKTKLELDDWIQANKIVDSAIELRDKAINTLKSTMNVKLDNDGSIDMNYLKRSCNDYERKLLSRIVDPSKVHGSFKDVRAPPSTIETLQSLISFPLLYPELFCKGILKKNFIPGVLLFGPPGTGKTMLAKAVAKESGSRMLDIQASDVYDMYVGQGEKNVKAIFSLARKLSPCVIFIDEVDSLMNKRGSDYSSKSHREIINQFMVEWDGLSSNNQGVVVMAATNRPFDLDDAVLRRMPRRILVDLPNEQDRAEILKVLLQDEQHEVPIEDXAKATEHYSGSDLKNVCVTAALKAVQQQVTTKTPQSLRMEHFEEALKMVPPSSSEEMDSLVEIRKWDSKFGDGKKKPKTTIGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NKT4</accession>
    <name>A0A1C7NKT4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Nucleoside diphosphate kinase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">nme6</name>
        <name evidence="10" type="ORF">A0J61_02185</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 7 8">Belongs to the NDK family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000079">
        <property type="protein sequence ID" value="OBZ89753.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NKT4"/>
    <dbReference type="STRING" id="101091.A0A1C7NKT4"/>
    <dbReference type="InParanoid" id="A0A1C7NKT4"/>
    <dbReference type="OrthoDB" id="2162449at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004550">
        <property type="term" value="F:nucleoside diphosphate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006241">
        <property type="term" value="P:CTP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006183">
        <property type="term" value="P:GTP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006228">
        <property type="term" value="P:UTP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.141">
        <property type="entry name" value="Nucleoside diphosphate kinase-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034907">
        <property type="entry name" value="NDK-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036850">
        <property type="entry name" value="NDK-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001564">
        <property type="entry name" value="Nucleoside_diP_kinase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46161">
        <property type="entry name" value="NUCLEOSIDE DIPHOSPHATE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46161:SF3">
        <property type="entry name" value="NUCLEOSIDE DIPHOSPHATE KINASE DDB_G0292928-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00334">
        <property type="entry name" value="NDK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01243">
        <property type="entry name" value="NUCDPKINASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00562">
        <property type="entry name" value="NDK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54919">
        <property type="entry name" value="Nucleoside diphosphate kinase, NDK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51374">
        <property type="entry name" value="NDPK_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 10" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Nucleoside diphosphate kinase-like" evidence="9">
        <location>
            <begin position="11"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="active site" description="Pros-phosphohistidine intermediate" evidence="7">
        <location>
            <position position="129"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="19"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="68"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="96"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="102"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="116"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="126"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008142"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00017632"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00706"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU004011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00562"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OBZ89753.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="149" mass="16974" checksum="0BDCB6E386D3D4FB" modified="2016-11-30" version="1">MSLRQLLKTKPQVTLALLKPDICANPALLPKIKEAIQHQQLEIVKERQVLWTEEDASQFYAEHKGKFFYHRLCSYMTSGPFTAMILASPEAIKDWRALIGPTHPVRARINQPDTLRALYGLTDTRNSFHGSDSDASAKKEIQFFFPEAC</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NL24</accession>
    <name>A0A1C7NL24_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">NET domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_02094</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000075">
        <property type="protein sequence ID" value="OBZ89853.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NL24"/>
    <dbReference type="STRING" id="101091.A0A1C7NL24"/>
    <dbReference type="InParanoid" id="A0A1C7NL24"/>
    <dbReference type="OrthoDB" id="2416617at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="146"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="17"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="37"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="151"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="201"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="211"/>
            <end position="228"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ89853.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="326" mass="37265" checksum="92118C590EDD45FF" modified="2016-11-30" version="1">MNSTIINEPLTAKRRTSSSTSSLSSYSSSSEEEDHNTFSTFYSQKSSMDSSGDEEEVEENYNTMKPSLMHRRQMEETILEKITQQLDAEKLPGILSIIAEKHEEHVEEVEIDLAKLNYIQLEQILLYIEACFREKNGGPKVKLADFVPKPVKTKPKPKNNRQRQKRRRSSLVGAGHVVNGSSTSRLSETHGPISMSTLTQLEREEKEMASTRRRNNRRKGPKKNKSRFNKMSPPVKKLPKRKTALHKRRLLEEMIQPSLSEEEEEEDDTKEGGIIIFGNEQMDFAVKDNQTIVHTSPSTGKKPIVPAIDYKSLEDDEDDEMIDIML</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NLA2</accession>
    <name>A0A1C7NLA2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Methyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_02327</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000086">
        <property type="protein sequence ID" value="OBZ89619.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NLA2"/>
    <dbReference type="FunCoup" id="A0A1C7NLA2">
        <property type="interactions" value="432"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NLA2"/>
    <dbReference type="InParanoid" id="A0A1C7NLA2"/>
    <dbReference type="OrthoDB" id="2013972at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041698">
        <property type="entry name" value="Methyltransf_25"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43591">
        <property type="entry name" value="METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43591:SF105">
        <property type="entry name" value="METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13649">
        <property type="entry name" value="Methyltransf_25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Methyltransferase" evidence="2">
        <location>
            <begin position="201"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="19"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="36"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="67"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="84"/>
            <end position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ89619.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="456" mass="52076" checksum="2EAF9C82FE43537C" modified="2016-11-30" version="1">MKRSKTGIETKKSSRRRSWLNNNPLFNIFTSAPSSPERRSSTELTRHRSHSLTPIDSPTTPPPVRPAPLKSSKSTLSSILSKASSKKKKKQHARKESSQTTYTFTDYSSIHESFCSSNRRSSNKSDATVVSDMDPYLMHDRYHQKSKPNSMQDGIGHQQQLIKSDEEEADRIQLKNDLVKLAFEGEFSLPFDYQKMKGGRVLDIGCGPGSWCIDLSTTYPNIHVVGVDSEDMFPCKHSLPSNCELIVCNVLNGLKEFPDASFDVIHIRFMVLAFTTRQYYQVVKDCWRLLKPKGYLEIFETDLTVYSAGPVTQKLNEEMFDVAISRGINPRELVNDLKHLVPSSSKSTTSTEDNLIHQQIKYRSIPIGVWGGRIGVLCRDDIVNILTKFQPAIRNFYGRSNYEQHAFERDVLAASREMEQYKSFTNYYSYTAQKPEIIEPIIRRQYTPPTFNPKSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NLM2</accession>
    <name>A0A1C7NLM2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Sialate O-acetylesterase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_02072</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000074">
        <property type="protein sequence ID" value="OBZ89870.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NLM2"/>
    <dbReference type="InParanoid" id="A0A1C7NLM2"/>
    <dbReference type="OrthoDB" id="42638at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1110">
        <property type="entry name" value="SGNH hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052940">
        <property type="entry name" value="Carb_Esterase_6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005181">
        <property type="entry name" value="SASA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036514">
        <property type="entry name" value="SGNH_hydro_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31988:SF19">
        <property type="entry name" value="9-O-ACETYL-N-ACETYLNEURAMINIC ACID DEACETYLASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31988">
        <property type="entry name" value="ESTERASE, PUTATIVE (DUF303)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03629">
        <property type="entry name" value="SASA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52266">
        <property type="entry name" value="SGNH hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Sialate O-acetylesterase" evidence="2">
        <location>
            <begin position="52"/>
            <end position="305"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03629"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ89870.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="431" mass="48151" checksum="ADE0D202847D57EE" modified="2016-11-30" version="1">MLYRLNEILLNQVLQRDSVTNCAAVIVDKEHVVRFEAGGPYFIQNKGPFYVGDVWVMAGQSNMRGHGLYYDPFTNQDLREPLKHSQLFLFDSSEQWLPFTYDPSHRLSISPRTVHHTLPDPTVKDPALLTYRGASLTNGFANAYQQLHPKVPLGLIACAHGGTSLYDWRPTVNEPDTSLYGAMIDKIKRSGHHVCGILWYQGESDATDPSFACHYAHKFKQWLANVRTDLSNPDLPVAMVQIGPHRLDKPNMIDLWDIVQDQQRQLFGITPFTAGAASLDADLDDRLHISARSLTVIGKRLAYAAEKARLGQGASATPLPSRAYCQSFSFHQLTMMTVVIEFDHLDTPWQLALNQQVSGFSLAVNETNEPVGLLKAMIEDPQKGSVRLYLISPTKNDLVINYGIHSSSGNLITTDGRALPAFYNFPVNNTQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NMB7</accession>
    <name>A0A1C7NMB7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="10">GTP-binding protein RHO1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">RHO1</name>
        <name evidence="10" type="ORF">A0J61_01820</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Lipid-anchor</topology>
            <orientation evidence="1">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the small GTPase superfamily. Rho family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000062">
        <property type="protein sequence ID" value="OBZ90140.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NMB7"/>
    <dbReference type="STRING" id="101091.A0A1C7NMB7"/>
    <dbReference type="InParanoid" id="A0A1C7NMB7"/>
    <dbReference type="OrthoDB" id="8830751at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007264">
        <property type="term" value="P:small GTPase-mediated signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000983">
        <property type="entry name" value="Rho family GTPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001806">
        <property type="entry name" value="Small_GTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003578">
        <property type="entry name" value="Small_GTPase_Rho"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24072">
        <property type="entry name" value="RHO FAMILY GTPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00071">
        <property type="entry name" value="Ras"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00449">
        <property type="entry name" value="RASTRNSFRMNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00175">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00176">
        <property type="entry name" value="RAN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00173">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00174">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51419">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51421">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51420">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="8" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0488">Methylation</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-0636">Prenylation</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004342"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010142"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023289"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OBZ90140.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="196" mass="22245" checksum="8949D1BFFF34FBAB" modified="2016-11-30" version="1">MTRGVARKKLVVVGDGGCGKTSLLVVYQRKAFPQRYVPTVFENYIANVPLDSGKIVELALWDTAGQEDYDRLRPLSYPETDVVLICFAINFRQSFTNVQDRWLPEVTHFCENVPKLLVGTKLDFRQNQEEIQRLSLAGQRLITVEEGEQLAREIGAKYYECSAMHKINVDEVIEAATKAAVAGNMKRLHKRLCKIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NMN0</accession>
    <name>A0A1C7NMN0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative inositol polyphosphate 5-phosphatase C9G1.10c</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_01570</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000051">
        <property type="protein sequence ID" value="OBZ90392.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NMN0"/>
    <dbReference type="STRING" id="101091.A0A1C7NMN0"/>
    <dbReference type="InParanoid" id="A0A1C7NMN0"/>
    <dbReference type="OrthoDB" id="2248459at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004439">
        <property type="term" value="F:phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046856">
        <property type="term" value="P:phosphatidylinositol dephosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.10.10">
        <property type="entry name" value="Endonuclease/exonuclease/phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036691">
        <property type="entry name" value="Endo/exonu/phosph_ase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046985">
        <property type="entry name" value="IP5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000300">
        <property type="entry name" value="IPPc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11200">
        <property type="entry name" value="INOSITOL 5-PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11200:SF240">
        <property type="entry name" value="INOSITOL POLYPHOSPHATE 5-PHOSPHATASE C9G1.10C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22669">
        <property type="entry name" value="Exo_endo_phos2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00128">
        <property type="entry name" value="IPPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56219">
        <property type="entry name" value="DNase I-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Inositol polyphosphate-related phosphatase" evidence="2">
        <location>
            <begin position="426"/>
            <end position="713"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="35"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="50"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="67"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="111"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="166"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="204"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="777"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ90392.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="777" mass="85840" checksum="449BB2D80F4B1848" modified="2016-11-30" version="1" fragment="single">MEGNEEQQSFQALKSKWAQQSLTKQEQSANTSPIISPPPIPPKPALHPKPAVDVEAKGTDREVPSKRVSTLTNQFETVNTPPGNFSNSQSPHHAAKISEDEDDPFYGSSDGDSDIEEDDDEENEEANMEGDTSLIQQVQKAHLQYTKLEEPRFVGAPGARSQDNLSVIPAPSPSVSSSSIRSTNGNKRPPPPPPPSRKYHNATKPISHTSICNGSIAPPIVQSPAPPPPVVDIPLASEPSNPSSTLQLPIAVEAVNVSPPVLPPRPTGSPLMPQLPPRPSQSTLARAHTIASAPHPKPLAVASFESSAPVLGSVEVDDNALRIRRANTTSTNKQRAMSRSELLITSSTCPDFSKATRNAPLIVLEKPFSTGHRSSLNAVAVTQNVLVTGASSLRTWDVHTGTVISTILTEGSNNNGGNSQNSDGGDRVRALAVAPSRIPADEGRYVWVARNDNSISVIDIRGGGAHKVLSKRHDVHMTSINFLLRYGNSEIWSIDDSGILNVWDVISSDYHAQQNPLLTAMPRRYHVTAHAVAATIYGSKLWMSSGRTLAAHTIPGILQSASFPRRDYADVFVHGGDGAMILDHEFCFLSGDLNYRIKMARKDVLRILANNNKKEAWEKLQEQDQLLRQKINNPLFKLLTFEEAPIQFDPTYKYDPGTDFYDSSEKKRVPAWCDRILYKGKNIQNLFYRRYEPRCSDHRPIAAGFSFETKITDQKKRDMLMSKVEEEWREHVERFIKDKKARYVADYEMCSLSEAFTRLEKSDWDVNDTVIKLLGEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NMR5</accession>
    <name>A0A1C7NMR5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">1-phosphatidylinositol-3-phosphate 5-kinase</fullName>
            <ecNumber evidence="2">2.7.1.150</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Type III PIP kinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="16" type="primary">fab1_1</name>
        <name evidence="16" type="ORF">A0J61_01508</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,5-bisphosphate) + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13609"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57923"/>
            <dbReference type="ChEBI" id="CHEBI:58088"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.150"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.150" evidence="2"/>
    <dbReference type="EMBL" id="LUGH01000049">
        <property type="protein sequence ID" value="OBZ90423.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="FunCoup" id="A0A1C7NMR5">
        <property type="interactions" value="668"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NMR5"/>
    <dbReference type="InParanoid" id="A0A1C7NMR5"/>
    <dbReference type="OrthoDB" id="158357at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010008">
        <property type="term" value="C:endosome membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000329">
        <property type="term" value="C:fungal-type vacuole membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000285">
        <property type="term" value="F:1-phosphatidylinositol-3-phosphate 5-kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046854">
        <property type="term" value="P:phosphatidylinositol phosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd03334">
        <property type="entry name" value="Fab1_TCP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd15725">
        <property type="entry name" value="FYVE_PIKfyve_Fab1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd17300">
        <property type="entry name" value="PIPKc_PIKfyve"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.810.10:FF:000001">
        <property type="entry name" value="1-phosphatidylinositol 3-phosphate 5-kinase FAB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.50.7.10:FF:000007">
        <property type="entry name" value="1-phosphatidylinositol 3-phosphate 5-kinase isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.800.10:FF:000005">
        <property type="entry name" value="1-phosphatidylinositol-3-phosphate 5-kinase (Fab1)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.810.10">
        <property type="entry name" value="2-Layer Sandwich"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.7.10">
        <property type="entry name" value="GroEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.800.10">
        <property type="entry name" value="Phosphatidylinositol Phosphate Kinase II Beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002423">
        <property type="entry name" value="Cpn60/GroEL/TCP-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027409">
        <property type="entry name" value="GroEL-like_apical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044769">
        <property type="entry name" value="PIKfyve_PIPKc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027483">
        <property type="entry name" value="PInositol-4-P-4/5-kinase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002498">
        <property type="entry name" value="PInositol-4-P-4/5-kinase_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027484">
        <property type="entry name" value="PInositol-4-P-5-kinase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000306">
        <property type="entry name" value="Znf_FYVE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017455">
        <property type="entry name" value="Znf_FYVE-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45748">
        <property type="entry name" value="1-PHOSPHATIDYLINOSITOL 3-PHOSPHATE 5-KINASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45748:SF7">
        <property type="entry name" value="1-PHOSPHATIDYLINOSITOL 3-PHOSPHATE 5-KINASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00118">
        <property type="entry name" value="Cpn60_TCP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01363">
        <property type="entry name" value="FYVE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01504">
        <property type="entry name" value="PIP5K"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00064">
        <property type="entry name" value="FYVE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00330">
        <property type="entry name" value="PIPKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52029">
        <property type="entry name" value="GroEL apical domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56104">
        <property type="entry name" value="SAICAR synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51455">
        <property type="entry name" value="PIPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50178">
        <property type="entry name" value="ZF_FYVE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="9 12" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7 12 16" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 12" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 12" id="KW-0808">Transferase</keyword>
    <keyword evidence="8" id="KW-0862">Zinc</keyword>
    <keyword evidence="6 11" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="FYVE-type" evidence="14">
        <location>
            <begin position="221"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="domain" description="PIPK" evidence="15">
        <location>
            <begin position="2064"/>
            <end position="2393"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="75"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="600"/>
            <end position="641"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1005"/>
            <end position="1040"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1883"/>
            <end position="1904"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="600"/>
            <end position="611"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="613"/>
            <end position="630"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="631"/>
            <end position="641"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="1893"/>
            <end position="1904"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000768"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012009"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00075294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50178"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51455"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="OBZ90423.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="2426" mass="273218" checksum="105AEAB4BA17F4AD" modified="2016-11-30" version="1">MDKERRSSLTTFNFQLPEEHNNDEGVLSKIFDKVLHAVSGPAAQDNTDRRTSSESDLKRDLSLASIPSIIQSQALTTPASTSSSLNKHLASTSSSSSVSVSKEQFNASGIPTAAVIPPSPASTTATTTATVTVGNQKLDALPLNETHTNSSVQFNVSDTKRPQEQEAIDYLLSSPLAKRRSIDSDTQSVITNFSISNSNSLSRILARLRGQKSDKEFWMPDEQCKECYKCRKPFTLLRRKHHCRICGQIFCSKCASHIISGKLYKQKGQVRVCNFCYAEQLQQLNDRSSTASLNTNQADYASSKIDTISKTASVSNLSHVLYNRGDEESIQSIQQPHKEHYSSAIIPSQKPPLEVPQMQIPTTALRQAKSIYGNDDATTTTFALELPTIASDTYVGTSPQTNHDLFGLNERSHSSGTPQGDLNIESPIMGHSNIVSANTATASNTDGMSNAGGFKRLFDAGTSLLKSTSRPRSNTSSSAPLEDTARQLHMSWAYPTSPYISDRGGGTVLAESELSPFPGNGNPAIDFYQDQLHHHQQYYDRYQQPTLGFSISSSLIPSVSAELYPAKSMLLEPTLSASHSSPNIPNDMLVLGSDDELYDQTRSKHKEDPRRNAATSARPSYNSYQRMNITNGNNSNGNKRSFRNSMIRINTTSLHKPGHFDNSDNWSSSPMLSPFVGDDSNSKFHPQSLESSNSIMAMNRFSFTNRQRRASGLPQNVELSLSARNHARRILRQLMNEIDLTQGSKEEWEEVIMNLLLKVTNHVRPDIRAGDDMDVRHYVKIKKVPGGLPSDSTYVKGVMCTKNVAHKRMVKNITNPRILILMFSLDYSRIEMENQLLSIAPVISQEREHVRKLIGRIVALKPSLLIVKSTVSRLALEFLLEANIPVIHNVKRSVIEAIARCTQASIVTSVDKLQHDLSFGRCGSFEIKTIMHEWIANRRKTFLVFDNCAPELGGTIVLRGEKMENLHAIKRLIDFMVFVVNNLKLETSLLLDSFAKSRGSLETEAESKSLPSIPTDHKKQAITGSTDSVPMSPLDEEGEHSTNSLYLDGLLKLYQNTILSVSQFVTFPPPYLLLVLKDTEDKLALIQNQKRRKSVSGSSVITNSTTINLKEAILTASPTKSTFEKQSLETYRFQQMNDDALMDTEFELMTKNHQTSRAWDAFIGENPESISPFYHQNIVVLYSSVCTVTTVPCQGPEIRIFGFYRYPSDKTLGQYIMDLCNDAQQSCSSFMCDHPMIQHYRSYAHGNARVNVMIEKFPCPLPGMSDKLLMWSYCRECNKPTPVLPMSDNTWNYSFGKFLEVFFYQTGVQCRADICPHDITRNHVRYFGYMDLTVRFQYDSINLLEVAVPPAKLFIHSQIQRDMKEAELKSLRQKINKFYQSVIDRNKAFPFDLVDPHKLEACKAELQDMSLEAQGEKKEALQLVQNVYATSDPHDTLTINVVHRSLFQVVSHWEAIYTDFVQYYLQPERELKKITANQLRKMFPTDITDSSSLKNTDNERTKRATETTDLPLIGIDLNDDDDILIDHNLKNQALNNVASKINQDYAMMPLLSTSPSECLPVLFDKKEQQELERKGTTNLQMSLADKSSNSKKSCLSPEIRRRLSLDLLHELNEKFKTTGDGNQPTGIISLNRMTSNKYLRVKSPGTLSAAYTPSQIPIIRQQDNSSSTMESSPGRQRSYTNAALALPEEGLQGKGMKNNRLLKKHHRHHSIGHGQEAYLQNMFKTQFGYEQEEESHNSFLRRSSTTKGDRCFRSRLPRKKTYIQVYTQANDLVIEDIDDEFSGGGEDAISIASRQERTSSKTRKCDGFLGSSISRRNTFASGLSRFHQYDSNVNQDEGDINILYDSDDNIEPIAPNLNEEIDYFTSLAPFANEVVEPERPSMKFNERRRKGLSTHSSSPSMTLSKSPVSFERSWLSFSDCPMDFSSGVSGEEEGDSCNLPKATDLLKIQAPSNNENLGFSDLQNIHPDIILNRVASVATKGGKSIAENLEEIRHSAEKSSFMKTLTNLLTDSGLGNLLPLEYPLQPTEHLFPDSYVVVKEDEPSTIIAYTLSSEDYLDKMHDIQDADTETGSHDGIMKPENASLLDAKAPSEVTTLDYGGSLHHTHMNDDIQETLRRESGSHMRYNFSTGSTKFFCKIFFSEQFDALRRNCGCDESYIMSLASCIKWDSSGGKSGSAFLKTKDDRLLMKQLSKYELDAFLRFAPAYFQYMSEAFFSELPTVLAKIFGFYSIGYKNSTTGKSMRMDVLIMENLFYQRNIKKIFDLKGSMRNRHVQSTGKQDEVLLDENLVELIYQSPLFIRAHSKEILRSSLHNDTLFLSNRNVMDYSLLVGIDEEKQELVVGIVDFIRTFTWDKKLESWVKESGILGGGGKEPTIVSPRQYRIRFREAMERYFLMVPDYWALSRQSKTSYSVLHYVTDRGESDEDM</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NMU3</accession>
    <name>A0A1C7NMU3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">OPT superfamily oligopeptide transporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">A0J61_01611</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the oligopeptide OPT transporter family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000053">
        <property type="protein sequence ID" value="OBZ90338.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NMU3"/>
    <dbReference type="STRING" id="101091.A0A1C7NMU3"/>
    <dbReference type="InParanoid" id="A0A1C7NMU3"/>
    <dbReference type="OrthoDB" id="627262at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000329">
        <property type="term" value="C:fungal-type vacuole membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035673">
        <property type="term" value="F:oligopeptide transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004813">
        <property type="entry name" value="OPT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045035">
        <property type="entry name" value="YSL-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00728">
        <property type="entry name" value="OPT_sfam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31645">
        <property type="entry name" value="OLIGOPEPTIDE TRANSPORTER YGL114W-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31645:SF0">
        <property type="entry name" value="OLIGOPEPTIDE TRANSPORTER YGL114W-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03169">
        <property type="entry name" value="OPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="51"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="92"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="172"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="233"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="278"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="348"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="374"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="413"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="461"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="516"/>
            <end position="534"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="598"/>
            <end position="624"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OBZ90338.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="629" mass="68984" checksum="603E79360C87B155" modified="2016-11-30" version="1">MCFSNMYFGLQTGWISMMSLQASLLGFALFKSWHRHIQPSFGPKENVYLQTVAVATATMPLAAGFVGILPALSQLTQEDHVDGSIVLSVSQLILWSLGLCLMGVFFAIPLRQQAIVREQLRFPSGTATAQMIELLHETKQDPQRDRIELTAYVDSDVDNDDLVTSIDRERTWALKLSALVISFSLSSVYTLASYFFPAIYALPVFNWLTLNLIDFKAWEWYFTPSLSYVGQGIIMGLPTTLSMLLGCVVGWGLLSPLAYFSGWAPGPIDDWKTGSKGWILWIALGIMIAESTISLLIVFSKQIYSMIYPSSSTLDEQQIGFLEYEEGPMSPKESSEDAPLHEQVPISVTLIGLVISVILCIIAIQVVFGNQTMPIGMTCISIAFAFFLSILGVRALGETDLNPVSGIGKMSQVAFAALMPGAIVANLIAGGIAEAGAQQAGDLMQDLKTGYLLGASPRAQLIGQLIGSCISSVVATVAYLLYTTIYTIPGPEFPAPTAQVWLDMSRLVNGHPLPPHVSEFVWFFAFLFGSFVILKETRHVPYLPQGIAFAIGMYNPPSFTLARVVGGLLVTLWDMYCHRSADHWFDRWFLNYKDLGQVAIVIIASGFVLGEGTCAIVNMILHAFEVPHF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NMU5</accession>
    <name>A0A1C7NMU5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">40S ribosomal protein S30</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">rps30a_0</name>
        <name evidence="6" type="synonym">rps30a_1</name>
        <name evidence="7" type="ORF">A0J61_01487</name>
        <name evidence="6" type="ORF">A0J61_10185</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the eukaryotic ribosomal protein eS30 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001063">
        <property type="protein sequence ID" value="OBZ81765.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="LUGH01000048">
        <property type="protein sequence ID" value="OBZ90461.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NMU5"/>
    <dbReference type="FunCoup" id="A0A1C7NMU5">
        <property type="interactions" value="269"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NMU5"/>
    <dbReference type="InParanoid" id="A0A1C7NMU5"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022627">
        <property type="term" value="C:cytosolic small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006846">
        <property type="entry name" value="Ribosomal_eS30"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12650">
        <property type="entry name" value="40S RIBOSOMAL PROTEIN S30/UBIQUITIN-LIKE PROTEIN FUBI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12650:SF15">
        <property type="entry name" value="RIBOSOMAL PROTEIN S30, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04758">
        <property type="entry name" value="Ribosomal_S30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 7" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="25"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU364011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OBZ81765.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OBZ90461.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="65" mass="7129" checksum="671AF81D22FDC692" modified="2016-11-30" version="1">MGKVHGSLARAGKVKSQTPKVAKQEKKKAKTGRAKKRQVYNRRFVNITSQIGGKRRMNPAPTAGP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NN73</accession>
    <name>A0A1C7NN73_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Zinc finger protein sfp1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">sfp1_0</name>
        <name evidence="8" type="ORF">A0J61_01497</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000048">
        <property type="protein sequence ID" value="OBZ90458.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NN73"/>
    <dbReference type="STRING" id="101091.A0A1C7NN73"/>
    <dbReference type="InParanoid" id="A0A1C7NN73"/>
    <dbReference type="OrthoDB" id="3269380at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051580">
        <property type="entry name" value="ZnF-Chromatin_assoc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23057">
        <property type="entry name" value="JUXTAPOSED WITH ANOTHER ZINC FINGER PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23057:SF0">
        <property type="entry name" value="JUXTAPOSED WITH ANOTHER ZINC FINGER PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="7">
        <location>
            <begin position="226"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="7">
        <location>
            <begin position="266"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="89"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="136"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="314"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="94"/>
            <end position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OBZ90458.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="334" mass="36592" checksum="8F8B2007546A53B7" modified="2016-11-30" version="1">MPVPVEFNHSVRRMSTITVPKQDINFDSYDFQFCQPQTDVRSAFEARELEASFCRDFACCGLVLEDLHDLLQHYEECHVRIEDEEGSFYDDSDSGSWSAPSSVPNSPLPSADDEQQIATLKKRAAAYLSDLYNSSVSCPPTPTEENLPEETDDSLPLISKRTGKKRAYGLISTPDAFELLTQSAAKKIVLASGDLPTPLFTDEDFLAQAGALLASANTNSNADKPYKCPVGGCDKAYKNPNGLKYHNQHGHCNMTADESESLSKPYQCTIGDCGKRYKNLNGLKYHIEHSHMAALNHTLAAFGSSLFSAISPSLPEEPTSSVSSPSSSSFSSFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NN89</accession>
    <name>A0A1C7NN89_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">dolichyl-phosphate beta-glucosyltransferase</fullName>
            <ecNumber evidence="4">2.4.1.117</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="primary">alg5</name>
        <name evidence="15" type="ORF">A0J61_01348</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>a di-trans,poly-cis-dolichyl phosphate + UDP-alpha-D-glucose = a di-trans,poly-cis-dolichyl beta-D-glucosyl phosphate + UDP</text>
            <dbReference type="Rhea" id="RHEA:15401"/>
            <dbReference type="Rhea" id="RHEA-COMP:19498"/>
            <dbReference type="Rhea" id="RHEA-COMP:19502"/>
            <dbReference type="ChEBI" id="CHEBI:57525"/>
            <dbReference type="ChEBI" id="CHEBI:57683"/>
            <dbReference type="ChEBI" id="CHEBI:58223"/>
            <dbReference type="ChEBI" id="CHEBI:58885"/>
            <dbReference type="EC" id="2.4.1.117"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="12">
            <dbReference type="Rhea" id="RHEA:15402"/>
        </physiologicalReaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the glycosyltransferase 2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.117" evidence="4"/>
    <dbReference type="EMBL" id="LUGH01000041">
        <property type="protein sequence ID" value="OBZ90601.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NN89"/>
    <dbReference type="FunCoup" id="A0A1C7NN89">
        <property type="interactions" value="529"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NN89"/>
    <dbReference type="InParanoid" id="A0A1C7NN89"/>
    <dbReference type="OrthoDB" id="3784at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004581">
        <property type="term" value="F:dolichyl-phosphate beta-glucosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006487">
        <property type="term" value="P:protein N-linked glycosylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd04188">
        <property type="entry name" value="DPG_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="entry name" value="Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035518">
        <property type="entry name" value="DPG_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001173">
        <property type="entry name" value="Glyco_trans_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10859:SF91">
        <property type="entry name" value="DOLICHYL-PHOSPHATE BETA-GLUCOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10859">
        <property type="entry name" value="GLYCOSYL TRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00535">
        <property type="entry name" value="Glycos_transf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="5" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="11 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0735">Signal-anchor</keyword>
    <keyword evidence="6 15" id="KW-0808">Transferase</keyword>
    <keyword evidence="7 13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10 13" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyltransferase 2-like" evidence="14">
        <location>
            <begin position="62"/>
            <end position="239"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006739"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012583"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00045097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF00535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="OBZ90601.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="312" mass="35496" checksum="061146FD65953363" modified="2016-11-30" version="1">MSFIQLLSGLITTVIALFIGFLLFCSPKPRARTKNEEYYRDATDEEKKKLPSLFDKASITLSCIVPAFDESQRLPKMLQETVSYLKDLKDLTFEVIIVDDGSRDKTIDVALKFAKQYPQVDIRILALDKNRGKGGAVTQGMLAARGEYCLMVDADGATQFSDLGQLLKEMKRIEKDGYGIVIGSRSHLVTTEAVVKRSFIRNFLMRSFHTLVYVLGIRGIEDTQCGFKLFTRKSAQTIFPNMHVERWIFDIECLMIAQIQKMPIAEVQVTWHEIDGSKVNLMVDSIKMAVDLLLIRMNYVLGFWSVKKVVQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NP62</accession>
    <name>A0A1C7NP62_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Tetratricopeptide repeat protein 39B</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">ttc39b_2</name>
        <name evidence="2" type="ORF">A0J61_01023</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000028">
        <property type="protein sequence ID" value="OBZ90923.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NP62"/>
    <dbReference type="InParanoid" id="A0A1C7NP62"/>
    <dbReference type="OrthoDB" id="43460at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019412">
        <property type="entry name" value="IML2/TPR_39"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31859">
        <property type="entry name" value="TETRATRICOPEPTIDE REPEAT PROTEIN 39 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31859:SF1">
        <property type="entry name" value="TETRATRICOPEPTIDE REPEAT PROTEIN 39C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10300">
        <property type="entry name" value="Iml2-TPR_39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="63"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="116"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="883"/>
            <end position="910"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="73"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="137"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="166"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="184"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="204"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="240"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="885"/>
            <end position="896"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="901"/>
            <end position="910"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ90923.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="910" mass="102355" checksum="870967C547D1FF77" modified="2016-11-30" version="1">MSSITDKQVLDAHIDKSDTKSVEHIQLEVSTQPKEFSDTREATNELSNVISALKESVVFEPVPSLENQDETSNEQLLTATSEPGSPRPTAIKTTTHHELMNHTVEIPAGQNMADYFTPPTPGMPPSSIELSENFSKLSKENVDENVKKEKNHCLELDDDTSSTNVEDNRDKMNAKVEDDDEEADAKSEEDGKGESDTDVKNNESEDDVEAKDNVLEDGTEDKDGEAKDNVEANDNNAKTEAIEAKDPSEGIEKSSDTSKETTIAAKKEEKPKDPHYIGPFNIDYDGVRANYINARSQEKYDADMVTGIELFFDNKFAEARAIFEKRTRQDPLYSLGLSSMAFARAFTSYNPKDLDTALARLTETFLFADAQVDAAFAKKPIADAVSHYFTNLLGTNPTNLPTKSSALNKYELQNRTFITNGALRAHIVRGESALLMSILYLAMDTTIGYIKAGENLRRAYGSYSYAWQEYKQMGQNYSRYIDRDSISGLQFGIGSVHLLLSSLPQKILKTVSAFCWSADKHLGFAMLKLCVEGKRTRSPIASLMLLSYYVTLTTHAPQVFTRELLQPAIECLLEAQKQYPNSAFFLFFAGRISRLARNIPVSTQSFVYTNEVCQGTWAEPALGDLASFEIIINSAMSLDWESMATKILELQPKYNNPALFKYLYGCCKEMTSDRTEAILSFAQISGLVDKRRNSQTELFIAHRVSFFEISGYQDLDFTLPVLELLMIWNLFPCMTATALEKCMELVDERLSLVYEREKMEYEIRKIELAPISTAPSYYDQRGVLLLIKASLLNALNRFSEGIVHLNWIIDNQDKFKFTNWIAPFAYWESGIVCWGTEDFKKARALWETGLTFTDFDFENKMSIRMHLAVQHAIELGVPETVVPKNKGKTNHGRKRLSIVPSKSSSKTSLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NP96</accession>
    <name>A0A1C7NP96_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Oligopeptide transporter 4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">OPT4</name>
        <name evidence="11" type="ORF">A0J61_01253</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the oligopeptide OPT transporter family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000037">
        <property type="protein sequence ID" value="OBZ90719.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NP96"/>
    <dbReference type="InParanoid" id="A0A1C7NP96"/>
    <dbReference type="OrthoDB" id="9986677at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035673">
        <property type="term" value="F:oligopeptide transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004648">
        <property type="entry name" value="Oligpept_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004813">
        <property type="entry name" value="OPT"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00727">
        <property type="entry name" value="ISP4_OPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00728">
        <property type="entry name" value="OPT_sfam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22601">
        <property type="entry name" value="ISP4 LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03169">
        <property type="entry name" value="OPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0571">Peptide transport</keyword>
    <keyword evidence="6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="87"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="112"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="151"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="183"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="243"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="316"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="390"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="453"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="479"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="511"/>
            <end position="531"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="563"/>
            <end position="584"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="630"/>
            <end position="651"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="709"/>
            <end position="732"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="25"/>
            <end position="36"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022856"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="OBZ90719.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="764" mass="86080" checksum="901DA1F40CCE6823" modified="2016-11-30" version="1">MAEDHNRADREEVLSEKVPTTNQQEKTEEVLNEKGHTDLDEPWIAEKYDTEKPPVYISGEDDLDIAIINDVSVTEDDPTMKVMTFRAVLTGVLLSALSSSVAQLMVFKPVGIALTDTFMLILAYVFCNAWAHYLPRGGWLNPGPFNMKEHACIFVMVSSANTSAYGTYILSAQELFYPNQVPSAAGGIFLLFATQMVGYGIAGQLRPYLVYPKTMTWPTSLPVVSLLKTLNTDRGEAKRRTRYFFLVFLAIFIYEFIPQYMFPMLGGISIICLAKNDSRWVQRLFGGLATNEGMGMFQLCFDWNLLSSYTPLVIPLWSQLNVFFGIFLLWIIAPLLYYYDVWHAQSFPYLSNSIYRLYDNGTSAIYPQDDVLNADSSLNQTALEEVGNPYFAAVYAFSYVAINLGVTSTMTHVALFYGKDILNYFRKTKKAVQEHEEDIHMRLMKAYKEVPTWWYYAVYVIGIGINIGICYANKSQLPWWGVIVAIAISTILSLPLNMISAITGYGFGLNVLTEMICGFVLPGYPVANMYFKTLGYNTMSQAGIMTKDLKIGHYLKVPPRLTFLNQMLGTSIGCIFNYIVNFTITQSKRDVLLDPVGNQFWNGATPQTINSAAITWGALGPMAMFGPGTAYYIVLWAFVIGFFLPVPFWLLHKKFPTVGFNFVNVPMIMIGLCFMPGSNTSWVTVSFLLILFTQGYVKRRHSDWFAKNNYLLSAALDSGTSLMVFFISMALYGGVSGNTYEFPVWWGNRADIDYIDQCCMNCSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-06-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NPK7</accession>
    <name>A0A1C7NPK7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_01574</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000052">
        <property type="protein sequence ID" value="OBZ90366.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NPK7"/>
    <dbReference type="InParanoid" id="A0A1C7NPK7"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ90366.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="111" mass="12670" checksum="FDDC2EE6BD24C95C" modified="2016-11-30" version="1">MLEFWDSTVTQHTITPTLLFDQRLLALAACSDKDKASIKQILNEQAIKSQCALLSVPKLIRQEPARFYWFEFRLNDDTDVSNTETVISSTLQQTKAEEQARVENVGLKKPN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NPV2</accession>
    <name>A0A1C7NPV2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">dolichyl-phosphate-mannose--protein mannosyltransferase</fullName>
            <ecNumber evidence="4">2.4.1.109</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="primary">PMT1_2</name>
        <name evidence="17" type="ORF">A0J61_00800</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>a di-trans,poly-cis-dolichyl beta-D-mannosyl phosphate + L-seryl-[protein] = 3-O-(alpha-D-mannosyl)-L-seryl-[protein] + a di-trans,poly-cis-dolichyl phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17377"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:13546"/>
            <dbReference type="Rhea" id="RHEA-COMP:19498"/>
            <dbReference type="Rhea" id="RHEA-COMP:19501"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:57683"/>
            <dbReference type="ChEBI" id="CHEBI:58211"/>
            <dbReference type="ChEBI" id="CHEBI:137321"/>
            <dbReference type="EC" id="2.4.1.109"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>a di-trans,poly-cis-dolichyl beta-D-mannosyl phosphate + L-threonyl-[protein] = 3-O-(alpha-D-mannosyl)-L-threonyl-[protein] + a di-trans,poly-cis-dolichyl phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:53396"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:13547"/>
            <dbReference type="Rhea" id="RHEA-COMP:19498"/>
            <dbReference type="Rhea" id="RHEA-COMP:19501"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:57683"/>
            <dbReference type="ChEBI" id="CHEBI:58211"/>
            <dbReference type="ChEBI" id="CHEBI:137323"/>
            <dbReference type="EC" id="2.4.1.109"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the glycosyltransferase 39 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.109" evidence="4"/>
    <dbReference type="EMBL" id="LUGH01000020">
        <property type="protein sequence ID" value="OBZ91151.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NPV2"/>
    <dbReference type="STRING" id="101091.A0A1C7NPV2"/>
    <dbReference type="InParanoid" id="A0A1C7NPV2"/>
    <dbReference type="OrthoDB" id="292747at2759"/>
    <dbReference type="UniPathway" id="UPA00378"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004169">
        <property type="term" value="F:dolichyl-phosphate-mannose-protein mannosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.80.10.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003342">
        <property type="entry name" value="ArnT-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036300">
        <property type="entry name" value="MIR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016093">
        <property type="entry name" value="MIR_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027005">
        <property type="entry name" value="PMT-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10050">
        <property type="entry name" value="DOLICHYL-PHOSPHATE-MANNOSE--PROTEIN MANNOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10050:SF46">
        <property type="entry name" value="PROTEIN O-MANNOSYL-TRANSFERASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02815">
        <property type="entry name" value="MIR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02366">
        <property type="entry name" value="PMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00472">
        <property type="entry name" value="MIR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82109">
        <property type="entry name" value="MIR domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50919">
        <property type="entry name" value="MIR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="5 17" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="11 15" id="KW-0472">Membrane</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0677">Repeat</keyword>
    <keyword evidence="6 17" id="KW-0808">Transferase</keyword>
    <keyword evidence="7 15" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10 15" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="93"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="131"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="184"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="232"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="263"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="601"/>
            <end position="619"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="650"/>
            <end position="671"/>
        </location>
    </feature>
    <feature type="domain" description="MIR" evidence="16">
        <location>
            <begin position="320"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="domain" description="MIR" evidence="16">
        <location>
            <begin position="384"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="837"/>
            <end position="883"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="14">
        <location>
            <begin position="842"/>
            <end position="863"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00045085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00045102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="OBZ91151.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="883" mass="101548" checksum="85D5F0373771D311" modified="2016-11-30" version="1">MFSVRSRKASDRQEKDPFIMEDDEKYGKKHYAYKESIWADKMQDRFRLFILTCLGLYLRVMNLEYPAFVVESELETTRQVNWYMASKFFIGKFPPLLGMIASGVTRVVGYYGTEDLIYPGQPFTEFPIITVRRFSALLGALLIPLCYLTLRNMNHSRSSATMAAALLVFENGIITQSRYATPEIYVLFFSALTTCLWTYMHTFSQESQNMLHMSALQTATGISMGCAISSKWTGILVFPMIWSSIVIDTWYKICDKKNRIKPVLIQIFGYLFTVGIVPLAVYLSIFCLHLQLIPNKGDHDLSLSTKLRYSLEGNNYDTSQPDIAYGSQIVIKHEATAGGYLHSHKKRFSGGSTQQEVTLYPHIDLNNIWTVHKAGELWNTSQPLEKVRNRDMIRLEHFSSSRKLHSHDVRPQISNRKEHSEVTAYGDKFIADHNDFWVLHIIDEQGYPSLNTSILWKPLEQRFRLQHIRGCALISHNIYYAPPEGENHQEVTCMASAHPVISNWIVESAFHDKLQNTTLITYNNPTLLQKIQEVHVLMYDYTNMIYDRLKAGGKGDTSTRSDSGNNQTPSAWLLKRTAMPLWNLMVGNATYMTLNPVVQRVSVTMIAVYFGYFALYTFLTKRQVKLPSCLTWLNATGMDAILHDHYTKSFYFFLYAFITQVVCLRFLPHHILSMPDILSAVYYGIGLTGVMLEACTSRWPSFWRRLCLYGLLLTSIIRFTQLSHLSYGGHKWTRSECEKSQLDIDCYKFPPSELERQELIKNNGNSSSFIFQLDLPLRSESYKYDMGEETEADKNVAILKQAVYLKEAQKATGIYRYHRVLPTPGISAEEAAAWTEEVTEGGFRREEEARRQQAEELQKKQEEEQQAANSNQPITEEAIEERA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NPW7</accession>
    <name>A0A1C7NPW7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Mediator of RNA polymerase II transcription subunit 9</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_01486</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000047">
        <property type="protein sequence ID" value="OBZ90476.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NPW7"/>
    <dbReference type="InParanoid" id="A0A1C7NPW7"/>
    <dbReference type="OrthoDB" id="2405052at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="3"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ90476.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="65" mass="7680" checksum="DCFFC99FA0993597" modified="2016-11-30" version="1" fragment="single">VAIQSLQQQVEQLKRIVNKKVDDLPDTTNQEALKEEIKQLKIANEKAEYRIRFLLRTLEQKETSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NQB1</accession>
    <name>A0A1C7NQB1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">A0J61_00649</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000015">
        <property type="protein sequence ID" value="OBZ91301.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NQB1"/>
    <dbReference type="STRING" id="101091.A0A1C7NQB1"/>
    <dbReference type="InParanoid" id="A0A1C7NQB1"/>
    <dbReference type="OrthoDB" id="2383663at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030677">
        <property type="term" value="C:ribonuclease P complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042781">
        <property type="term" value="F:3'-tRNA processing endoribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004526">
        <property type="term" value="F:ribonuclease P activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_Su5_D2-typ_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribsml_uS5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000100">
        <property type="entry name" value="RNase_P"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33992">
        <property type="entry name" value="RIBONUCLEASE P PROTEIN COMPONENT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33992:SF1">
        <property type="entry name" value="RIBONUCLEASE P PROTEIN COMPONENT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00825">
        <property type="entry name" value="Ribonuclease_P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="Ribosomal protein S5 domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0540">Nuclease</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="1" id="KW-0819">tRNA processing</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="114"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="118"/>
            <end position="135"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OBZ91301.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="135" mass="15357" checksum="5910D14201D63AC4" modified="2016-11-30" version="1">MKIPGIHSERLFAIFSKQSNLRTSTDLFNIKALPNGTLDLNRFALITSKKNISKSAVIRNRADRRIKAALQTEHDVITVKGYDFLFYLKPALVTAPWTTITTELASSLKKIQHMASTKPKKRAPHHQYKKTKSHD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NQU5</accession>
    <name>A0A1C7NQU5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Ecotropic viral integration site 5 like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">Evi5</name>
        <name evidence="4" type="ORF">A0J61_00525</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000012">
        <property type="protein sequence ID" value="OBZ91398.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NQU5"/>
    <dbReference type="STRING" id="101091.A0A1C7NQU5"/>
    <dbReference type="InParanoid" id="A0A1C7NQU5"/>
    <dbReference type="OrthoDB" id="159449at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031267">
        <property type="term" value="F:small GTPase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.270:FF:000001">
        <property type="entry name" value="TBC1 domain family member 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.270">
        <property type="entry name" value="putative rabgap domain of human tbc1 domain family member 14 like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.750">
        <property type="entry name" value="Ypt/Rab-GAP domain of gyp1p, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000195">
        <property type="entry name" value="Rab-GAP-TBC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035969">
        <property type="entry name" value="Rab-GAP_TBC_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050302">
        <property type="entry name" value="Rab_GAP_TBC_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47219">
        <property type="entry name" value="RAB GTPASE-ACTIVATING PROTEIN 1-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47219:SF22">
        <property type="entry name" value="RAB-GAP TBC DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00566">
        <property type="entry name" value="RabGAP-TBC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47923">
        <property type="entry name" value="Ypt/Rab-GAP domain of gyp1p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50086">
        <property type="entry name" value="TBC_RABGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0343">GTPase activation</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rab-GAP TBC" evidence="3">
        <location>
            <begin position="159"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="27"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="32"/>
            <end position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022468"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OBZ91398.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="264" mass="30073" checksum="7132937B560F3C0E" modified="2016-11-30" version="1">MYNDDTLLSESCVTSKEDETMHFSLLPDNPRSSRSSLTTVETSSTTNTKSLYGSTKEENQTLFDRLKEENAKLPPQDSTAFILALVERQNVLLERDPKSIYIHSNKLKANFSTVQKLVHGNMDEIEEDIDWGFWEAVIEDSDQVALKLPHLLSLKLKSGIPSKVRGLIWQAMSKSASLHLETVYKQLCSERSPHERIIQRDLSRTFPRIDMFKQEDGHGQNAMKRILEAYSLYDTEVGYCQGLAFLVGPLLMNVVYYCSLKITS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NRC9</accession>
    <name>A0A1C7NRC9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative methyltransferase C70.08c</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">SPCC70.08c</name>
        <name evidence="2" type="ORF">A0J61_00268</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000005">
        <property type="protein sequence ID" value="OBZ91687.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NRC9"/>
    <dbReference type="InParanoid" id="A0A1C7NRC9"/>
    <dbReference type="OrthoDB" id="6329284at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008757">
        <property type="term" value="F:S-adenosylmethionine-dependent methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013216">
        <property type="entry name" value="Methyltransf_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43861:SF1">
        <property type="entry name" value="TRANS-ACONITATE 2-METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43861">
        <property type="entry name" value="TRANS-ACONITATE 2-METHYLTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08241">
        <property type="entry name" value="Methyltransf_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransferase type 11" evidence="1">
        <location>
            <begin position="39"/>
            <end position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF08241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ91687.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="264" mass="29882" checksum="C464C72C101FD808" modified="2016-11-30" version="1">MSIQDDWSASNYAKHASFVPKLGSVILDMLDPQPDERILDFGCGDGVLTEILAARCQAVTGIDSSQDMIQAAKKQQRDSNTSYHVVDGYHLDQWFDGQTRNNSLYXAVFSNATLHWLKKDPAKVIENIHHVLRPKGRFVAEFGGFMNVGEIHAALINGLCKRGLDGNAISPWYFPSAESYSQLLEQNGFKVVEANLTPRATLLNTDIVGWIETFGFEFLKVLPDDEERKKLAQEVQLQLQPCYQRENGRWFTMYTRLRIVAVKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NRL2</accession>
    <name>A0A1C7NRL2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_00175</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000004">
        <property type="protein sequence ID" value="OBZ91762.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NRL2"/>
    <dbReference type="STRING" id="101091.A0A1C7NRL2"/>
    <dbReference type="InParanoid" id="A0A1C7NRL2"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="7"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ91762.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="198" mass="21170" checksum="2496B4B09249B7F5" modified="2016-11-30" version="1" fragment="single">KEEDHKEEDHKEEDHKEEDHKEEDGDKKDDSKDDDKAEEDKKEDDKKEDDKTEEDKKDDEKKEDGKAEEIKKEDSKEGEKKEDNKEQAKVDAKDHSKEDDKKKASAGQAIHANAFSVAQVSSISSRVSSALSASASASASSSGLAASITSSVSSRISSAISSAASAATSSRASSGATNIRVGGAFIATAAGFVAYMLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NS45</accession>
    <name>A0A1C7NS45_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Oligopeptide transporter 5</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">OPT5_0</name>
        <name evidence="10" type="ORF">A0J61_00152</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the oligopeptide OPT transporter family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000003">
        <property type="protein sequence ID" value="OBZ91800.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="FunCoup" id="A0A1C7NS45">
        <property type="interactions" value="10"/>
    </dbReference>
    <dbReference type="InParanoid" id="A0A1C7NS45"/>
    <dbReference type="OrthoDB" id="9986677at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035673">
        <property type="term" value="F:oligopeptide transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004648">
        <property type="entry name" value="Oligpept_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004813">
        <property type="entry name" value="OPT"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00727">
        <property type="entry name" value="ISP4_OPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00728">
        <property type="entry name" value="OPT_sfam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22601">
        <property type="entry name" value="ISP4 LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03169">
        <property type="entry name" value="OPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0571">Peptide transport</keyword>
    <keyword evidence="6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="64"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="168"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="239"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="280"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="309"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="441"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="467"/>
            <end position="490"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="551"/>
            <end position="572"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="584"/>
            <end position="605"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="617"/>
            <end position="638"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="664"/>
            <end position="683"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="695"/>
            <end position="717"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022856"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OBZ91800.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="752" mass="84181" checksum="1EE827F9331DAB9D" modified="2016-11-30" version="1">MELDKKQQPTYGTNEVVYPDSIKSSSGKVTINEDAYQEDSPIEEVRSSIPPTDDTTLPTATFRSWFWGIVFSAAISFTNQFFWFRANPLTIKVIVVQLLAFPAGILTEKILPDFTIPLGRFSFSLNPGPFSVKEHVLITVMANAAATSFDAIDIIVVQKLYYNQDWGFGGGILLVLTTSLLGFGFAGILRRFLVRPAAMVWPINLVNATLFHTLHRKVPKEVEDAEAVTPGLGLSRNKFFLIAFGASFCWYFFPGYIMPILTSISWICWIKKDSILVSQIGSGISGLGVASFTLDWSSLAAWYPSPLAIPWVVQANMLAGFVFFIYILVPIIYXTDTWESKKFPFYNTHQYDIWGNPFNRTRVLTPDQYLDEEAYANYSPIRITGFFAVCYGQGLAALGAIITHTILYNGKEIWNRVKSARQSDDDIHARLMDHYKEVPDLWYAILFVIALALSFVTIILWPSNMPWWTLIIAVILALAWLLPIGIITAITSQSPTISMISEWVFGAIHPGNPIGNMMFKTYGYITVRQALLFAQDLKLGHYMKIPPRHMFTFQVVGTIIASFVSLGTTNYLMNSIPNICTSSAYPWTCPNAGLFGASSVIWGLIGPNKFFAPDSLYHGLPYFLLAGFLAPIPIYFLAKRYPDSWVANINIPVFMLGIAPFPPAPTNITTTWALIGFIFNFVIKRRAVAWWKKYNYVLSAALDSGVAICAIVIFFAFQYSNINFPTWWGNSTGSVDQCPLATANWNGTDVYA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NS61</accession>
    <name>A0A1C7NS61_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">A0J61_00065</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000001">
        <property type="protein sequence ID" value="OBZ91937.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NS61"/>
    <dbReference type="InParanoid" id="A0A1C7NS61"/>
    <dbReference type="OrthoDB" id="2287072at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="3">
        <location>
            <begin position="15"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="101"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="103"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="116"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="139"/>
            <end position="149"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OBZ91937.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="180" mass="20705" checksum="9A8F9B4E4E62834E" modified="2016-11-30" version="1">MVVTSKEKEVVKFIYACSICGDSFRGAVQSIDHYLRIHGYSAPRRSIGRRRPPHPDYDYQNKADGDCDCEHYACGSCWFHVPATKEGLEDLRDHFFNAHHPKKVDTSKDSGKDYEPDNMEEEQEETEEDGGEEEDQKEKVKKGPNRRKSTSSAQPDNKEDMTTVLQKLNELSDLFKNLMK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NTJ4</accession>
    <name>A0A1C7NTJ4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="19">Putative thiamine biosynthetic bifunctional enzyme</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="19" type="primary">thi4</name>
        <name evidence="19" type="ORF">A0J61_01143</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="19 20" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19 20">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>2-(2-carboxy-4-methylthiazol-5-yl)ethyl phosphate + 4-amino-2-methyl-5-(diphosphooxymethyl)pyrimidine + 2 H(+) = thiamine phosphate + CO2 + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:47848"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:37575"/>
            <dbReference type="ChEBI" id="CHEBI:57841"/>
            <dbReference type="ChEBI" id="CHEBI:62890"/>
            <dbReference type="EC" id="2.5.1.3"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="15">
            <text>2-[(2R,5Z)-2-carboxy-4-methylthiazol-5(2H)-ylidene]ethyl phosphate + 4-amino-2-methyl-5-(diphosphooxymethyl)pyrimidine + 2 H(+) = thiamine phosphate + CO2 + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:47844"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:37575"/>
            <dbReference type="ChEBI" id="CHEBI:57841"/>
            <dbReference type="ChEBI" id="CHEBI:62899"/>
            <dbReference type="EC" id="2.5.1.3"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>4-methyl-5-(2-phosphooxyethyl)-thiazole + 4-amino-2-methyl-5-(diphosphooxymethyl)pyrimidine + H(+) = thiamine phosphate + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:22328"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:37575"/>
            <dbReference type="ChEBI" id="CHEBI:57841"/>
            <dbReference type="ChEBI" id="CHEBI:58296"/>
            <dbReference type="EC" id="2.5.1.3"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>5-(2-hydroxyethyl)-4-methylthiazole + ATP = 4-methyl-5-(2-phosphooxyethyl)-thiazole + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:24212"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17957"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:58296"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.50"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="4">Cofactor biosynthesis; thiamine diphosphate biosynthesis; 4-methyl-5-(2-phosphoethyl)-thiazole from 5-(2-hydroxyethyl)-4-methylthiazole: step 1/1.</text>
    </comment>
    <comment type="pathway">
        <text evidence="5">Cofactor biosynthesis; thiamine diphosphate biosynthesis; thiamine phosphate from 4-amino-2-methyl-5-diphosphomethylpyrimidine and 4-methyl-5-(2-phosphoethyl)-thiazole: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="16">In the C-terminal section; belongs to the Thz kinase family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="17">In the N-terminal section; belongs to the thiamine-phosphate synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="19">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000033">
        <property type="protein sequence ID" value="OBZ90814.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NTJ4"/>
    <dbReference type="FunCoup" id="A0A1C7NTJ4">
        <property type="interactions" value="343"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NTJ4"/>
    <dbReference type="InParanoid" id="A0A1C7NTJ4"/>
    <dbReference type="OrthoDB" id="4994at2759"/>
    <dbReference type="UniPathway" id="UPA00060">
        <property type="reaction ID" value="UER00139"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004417">
        <property type="term" value="F:hydroxyethylthiazole kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004789">
        <property type="term" value="F:thiamine-phosphate diphosphorylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009228">
        <property type="term" value="P:thiamine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009229">
        <property type="term" value="P:thiamine diphosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd01170">
        <property type="entry name" value="THZ_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00564">
        <property type="entry name" value="TMP_TenI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.70:FF:000104">
        <property type="entry name" value="Thiamine biosynthetic bifunctional enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1190.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00228">
        <property type="entry name" value="Thz_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00097">
        <property type="entry name" value="TMP_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000417">
        <property type="entry name" value="Hyethyz_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029056">
        <property type="entry name" value="Ribokinase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036206">
        <property type="entry name" value="ThiamineP_synth_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022998">
        <property type="entry name" value="ThiamineP_synth_TenI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034291">
        <property type="entry name" value="TMP_synthase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006830">
        <property type="entry name" value="PRK09355.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00693">
        <property type="entry name" value="thiE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00694">
        <property type="entry name" value="thiM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20857:SF23">
        <property type="entry name" value="THIAMINE BIOSYNTHETIC BIFUNCTIONAL ENZYME"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20857">
        <property type="entry name" value="THIAMINE-PHOSPHATE PYROPHOSPHORYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02110">
        <property type="entry name" value="HK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02581">
        <property type="entry name" value="TMP-TENI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01099">
        <property type="entry name" value="HYETHTZKNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53613">
        <property type="entry name" value="Ribokinase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51391">
        <property type="entry name" value="Thiamin phosphate synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9" id="KW-0418">Kinase</keyword>
    <keyword evidence="11" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="12" id="KW-0784">Thiamine biosynthesis</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Thiamine phosphate synthase/TenI" evidence="18">
        <location>
            <begin position="10"/>
            <end position="201"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00003814"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004868"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00005165"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00047334"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00047851"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00047883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00061146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00061283"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="Pfam" id="PF02581"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="OBZ90814.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="506" mass="53969" checksum="F1B13CE3CCDA2D0F" modified="2016-11-30" version="1">MSIKKIDYSLYLVTDRSLVPEGKTFLGQIERALEGGVTIVQLREKDTDTGPFIELAHQVKALTRKYGVPLIINDRLDVAQAIDAEGVHIGQDDMPLTQARHILGPKKIIGVSCNTEEEAAIAIRDGADYLGIGAVWFTSTKKNIKEPLGVAGVQRILKSMEANPVPTVAIGGISAQNACELLEGSSTEKLYIDGLAIVSAIMAAEDPKVVCEELVQLIKKSFRTMGVRSISSVDQVIEHAIRAAINIKNKTPMIHHMTNYVVINDNANATLAVGASPIMSTNGQELEDLAAVNGAMLLNLGTLNDVNLMISAAQVNAAHKNPVILDPVGCGATQFRKETTARFLDECDLTVIKGNAGEILSLAGLGGKSRGVDSVGINDEQVMVDAVKRLARQNNCVVGLTGPVDYISDGDHVYAIENGSKYLPLITGSGCLVSSVVACFAAANRDNYLLATVAGILTVTVASEIAAKRSYVNGPGTFRAALIDELYNLTNSPALFRDYAKIRIIC</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NTV7</accession>
    <name>A0A1C7NTV7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">chitin synthase</fullName>
            <ecNumber evidence="2">2.4.1.16</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="primary">chs1</name>
        <name evidence="17" type="ORF">A0J61_01008</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Polymerizes chitin, a structural polymer of the cell wall and septum, by transferring the sugar moiety of UDP-GlcNAc to the non-reducing end of the growing chitin polymer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.16" evidence="2"/>
    <dbReference type="EMBL" id="LUGH01000027">
        <property type="protein sequence ID" value="OBZ90934.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NTV7"/>
    <dbReference type="STRING" id="101091.A0A1C7NTV7"/>
    <dbReference type="InParanoid" id="A0A1C7NTV7"/>
    <dbReference type="OrthoDB" id="26569at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030428">
        <property type="term" value="C:cell septum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004100">
        <property type="term" value="F:chitin synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006031">
        <property type="term" value="P:chitin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010960">
        <property type="term" value="P:magnesium ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd04590">
        <property type="entry name" value="CBS_pair_CorC_HlyC_assoc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd04190">
        <property type="entry name" value="Chitin_synth_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.580.10:FF:000006">
        <property type="entry name" value="DUF21 and CBS domain protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.580.10">
        <property type="entry name" value="CBS-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000644">
        <property type="entry name" value="CBS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046342">
        <property type="entry name" value="CBS_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004835">
        <property type="entry name" value="Chitin_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013616">
        <property type="entry name" value="Chitin_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002550">
        <property type="entry name" value="CNNM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044751">
        <property type="entry name" value="Ion_transp-like_CBS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22914">
        <property type="entry name" value="CHITIN SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22914:SF9">
        <property type="entry name" value="CHITIN SYNTHASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00571">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01644">
        <property type="entry name" value="Chitin_synth_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08407">
        <property type="entry name" value="Chitin_synth_1N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01595">
        <property type="entry name" value="CNNM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54631">
        <property type="entry name" value="CBS-domain pair"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51371">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51846">
        <property type="entry name" value="CNNM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="12" id="KW-0129">CBS domain</keyword>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="10" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="4" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="9 13 14" id="KW-0472">Membrane</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="6 13 14" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 13 14" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="477"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="524"/>
            <end position="544"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="556"/>
            <end position="584"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="604"/>
            <end position="623"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="732"/>
            <end position="753"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="765"/>
            <end position="783"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="803"/>
            <end position="822"/>
        </location>
    </feature>
    <feature type="domain" description="CNNM transmembrane" evidence="16">
        <location>
            <begin position="795"/>
            <end position="984"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="15">
        <location>
            <begin position="1065"/>
            <end position="1127"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012543"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00024009"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS51846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="OBZ90934.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="1170" mass="132929" checksum="2F00FC91D4E9C3AD" modified="2016-11-30" version="1">MDDKQYYYYMPSQIARPTAPLPTLVSPNDMYTIPQHNEDYIDNDPYSTFPPFRQARRYKTVKQLVHIPQGKLILNCPVPIQYLERVPLRDSPEFSNMRYTAITCDPSEFQPQGYTLRQDFMKRDTEIAICITMYNEDEILLSRTLHGIMKNIYQLTKRHRSSIWGENAWKKIVVCIIADGREKINRRVLDMLSVLGLYQEGIAKNAVNGKQVHAHLYEYTTQLCLTPDLTYQGALDGIVPTQVVFCLKEKNQRKINSHRWFFQAMCPILKPNVCILLDVGTKPGPHSIYKLWQPFHKFRDVGGACGEIKAMTGKGGVYLLNPLVGAQNFEYKISNILDKPLESLLGYIQVLPGAFSAYRYSAIQNDLMTQEGPLKKYFLGDTSSPLTASLEGIFDANMYLAEDRILCYELVAKRNSQWRLHYVAGAYGETDVPFTIAEFISQRRRWLNGSFFAGVYSLVHWGKILNTNHTGKRKLLLLIELIYLCISWLFSWFALGNFFISFYILTRSLSTMSYPPFDQNAADVIHIAFTYIYAVLIICLFLMSMGNRPQGSQASYGMIMVFFAMLMLYVVFASVWIAYIGIFTELSKPQSGIGLLSNGPFRDIVISVTSTLGIYILSGLLYFDPWHMITSFLQYFLLAPSYINILNTYAFCNTHDVSWGTKDITLVPYLGHVETKIDETTAEVTLPEQQDVGYLYEVSAQSLQQKMDSRKSIFTDPKQRQEDYYRNFRTRLVVCWILTNLVLVIVICTIDNLGRLGNFDDRTNVYLSFLLWCVAGLAAFRFVGSTLYRLQETAKTFELYERLLCIIFLVLIGGVFAGMYLWNSSRGLGLTIGLMGLDQTNLHVLMETGSPFEKENARKVSSLLDRGKHWVLVTLLLSNVIVNETLPIVLHGVLSGGWQAVVLSTALIVIFGDHMRSTRFSYWREDILTLMYVMYPIAYPIAKLLDYVLGESHGTVYKKAGLKSLVSLHQAVHPSDVDALTSDEVTIIGAVLDLKQKPVSLIMTPISDVFTLSKDDVLDEALVDKILTAGYSRIPIHASEDDTRFVGMLLTKRLITYDPEDALPVQQLPLSALPETGSETSCLDILNFFQEGKSHMALVNDDTNTVIGVITLEDVIEELIGEEIIDETDVYVDVRNKIRVVRRHMINKRSAIAKQAIRHKLIEKSTYGAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NU13</accession>
    <name>A0A1C7NU13_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_00928</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000025">
        <property type="protein sequence ID" value="OBZ90994.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NU13"/>
    <dbReference type="InParanoid" id="A0A1C7NU13"/>
    <dbReference type="OrthoDB" id="2398733at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="165"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="13"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="64"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="76"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="93"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="165"/>
            <end position="177"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ90994.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="242" mass="27432" checksum="2D5B1479D82830A2" modified="2016-11-30" version="1">MDNNPFRNNQSPPMNGNYSYMSSNYQSQQPPLQQQQQQQQQQQQQLPYQQSYNTGYPTPPNGYQQQPQSWQLQQQISNTPMMSQQTSSFSNYPSQTQTSMVSSSLSPLSKGQYSAYTNNNDLMSSSVSSSNNFGNTQSSYGLSFSMPNTNSFPANTNSMYMQQQYPSFQQQQQQSSSNFYIPPNFGMSNYTSPPPSQPRHPPVDASSLLKGTQIRRVECPTCQKMIEGDDMAINHHVNQHFT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NV28</accession>
    <name>A0A1C7NV28_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Protein YOP1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">REEP5_1</name>
        <name evidence="8" type="ORF">A0J61_00596</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Membrane</location>
            <topology evidence="1 6">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the DP1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000014">
        <property type="protein sequence ID" value="OBZ91334.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NV28"/>
    <dbReference type="InParanoid" id="A0A1C7NV28"/>
    <dbReference type="OrthoDB" id="10009287at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004345">
        <property type="entry name" value="TB2_DP1_HVA22"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12300">
        <property type="entry name" value="HVA22-LIKE PROTEINS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12300:SF161">
        <property type="entry name" value="RECEPTOR EXPRESSION-ENHANCING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03134">
        <property type="entry name" value="TB2_DP1_HVA22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0675">Receptor</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="182"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="227"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="186"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="227"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="250"/>
            <end position="266"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008573"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU362006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OBZ91334.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="281" mass="32542" checksum="F093978D021BEC5F" modified="2016-11-30" version="1">MPLKHDLTSKLVEDWLNSLNHSAPINLTFVTEPLSKAVTGRVRSLEEIYHTFTVYRFLSRKGVYPLLLFTATSSSIGYSLFRAYTKSTKFVLSLVGVLYPAYRSWKLIKDIPSDRSDDKLERWLTYWLIYGSFQVFDHWVASDYFTSSRRKYNFYKLLILYWAQSPHSDGASLIYRHVIQKPQNRQRREEENKKKEVEECTTTNGSEASVMPYRYLDEFQSPTVDHHEDTFHCSKDNHSSSSSSSDDDSIGSTHQHDSNLTTSEKSSFPPLLMSVSTEAAW</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NVP2</accession>
    <name>A0A1C7NVP2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">chitin synthase</fullName>
            <ecNumber evidence="2">2.4.1.16</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="primary">CHS8_6</name>
        <name evidence="17" type="ORF">A0J61_00407</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="12">Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.16" evidence="2"/>
    <dbReference type="EMBL" id="LUGH01000009">
        <property type="protein sequence ID" value="OBZ91544.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NVP2"/>
    <dbReference type="InParanoid" id="A0A1C7NVP2"/>
    <dbReference type="OrthoDB" id="370884at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030428">
        <property type="term" value="C:cell septum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016459">
        <property type="term" value="C:myosin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003779">
        <property type="term" value="F:actin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004100">
        <property type="term" value="F:chitin synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003774">
        <property type="term" value="F:cytoskeletal motor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006031">
        <property type="term" value="P:chitin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031505">
        <property type="term" value="P:fungal-type cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.530">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.120.10">
        <property type="entry name" value="Cytochrome b5-like heme/steroid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.850.10">
        <property type="entry name" value="Kinesin motor domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.720">
        <property type="entry name" value="Myosin VI head, motor domain, U50 subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004835">
        <property type="entry name" value="Chitin_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001199">
        <property type="entry name" value="Cyt_B5-like_heme/steroid-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036400">
        <property type="entry name" value="Cyt_B5-like_heme/steroid_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036961">
        <property type="entry name" value="Kinesin_motor_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001609">
        <property type="entry name" value="Myosin_head_motor_dom-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22914">
        <property type="entry name" value="CHITIN SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22914:SF45">
        <property type="entry name" value="CHITIN SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03142">
        <property type="entry name" value="Chitin_synth_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00173">
        <property type="entry name" value="Cyt-b5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00063">
        <property type="entry name" value="Myosin_head"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00193">
        <property type="entry name" value="MYOSINHEAVY"/>
    </dbReference>
    <dbReference type="SMART" id="SM01117">
        <property type="entry name" value="Cyt-b5"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00242">
        <property type="entry name" value="MYSc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55856">
        <property type="entry name" value="Cytochrome b5-like heme/steroid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50255">
        <property type="entry name" value="CYTOCHROME_B5_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51456">
        <property type="entry name" value="MYOSIN_MOTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-0009">Actin-binding</keyword>
    <keyword evidence="12" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="11" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="4" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="9 14" id="KW-0472">Membrane</keyword>
    <keyword evidence="10 12" id="KW-0505">Motor protein</keyword>
    <keyword evidence="8 12" id="KW-0518">Myosin</keyword>
    <keyword evidence="12" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="6 14" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 14" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="837"/>
            <end position="856"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="876"/>
            <end position="895"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="1142"/>
            <end position="1161"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="1537"/>
            <end position="1558"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="1564"/>
            <end position="1585"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="1592"/>
            <end position="1615"/>
        </location>
    </feature>
    <feature type="domain" description="Myosin motor" evidence="16">
        <location>
            <begin position="9"/>
            <end position="716"/>
        </location>
    </feature>
    <feature type="domain" description="Cytochrome b5 heme-binding" evidence="15">
        <location>
            <begin position="902"/>
            <end position="1000"/>
        </location>
    </feature>
    <feature type="region of interest" description="Actin-binding" evidence="12">
        <location>
            <begin position="594"/>
            <end position="616"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1750"/>
            <end position="1779"/>
        </location>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <begin position="112"/>
            <end position="119"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012543"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS51456"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="OBZ91544.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="1779" mass="202935" checksum="C92E839C8EB6ACC0" modified="2016-11-30" version="1">MSLSEREAEAVTDLCNINDVNNKKIINVLHSRFTGYNVYTYLGTLGLVSINPSRYLAQNDEQTSEEYVAIYRNTSLETISTKTLNPHLFGLVNRAFFHMRRTGRDQVVLLCGESGSGKTENSKLIIQHLLRLSNSKKQNKLYQAIQNVHQVLNAFGCAKTGYNKQAASRYGAYTELHFNERGKLVGAKTLEYSLEKSRLSNTCHRPSEGNFNIFYWLLAGTSPDEKQTLQLKESPKDYPYLAHYGRDLLEEDAMHYKDLKSAMRTVGIRKEHISRIIQLLAAILHLGTLQFNSSAEEGLAIHSQEILETIADLLGLESEALGSVLRFRTVMIGNDTTTLILTEDQAIIQRDRLAEVLYSLLFSWIVSHINRKTYTDHFSALFSLVDFPGTQSTGFGAVGFEQFCINYANERIYHFLHTHSFNHQELAIDGLQIPMIENPISTACIDLFEQPNRGIRAIVDGHSIHCNRKTATEEEQAMLTAIKQHNYQNPALSFRYSDTGARQFAVQHFSGKVYYDTNSFIAKNTNESLDDFVSLFRGTAESPGSWNSLMLSLFSDENLPMDNIRPSPEEPSEKMVQTENVTPRTVLSQIGSSLDDLLDSFRDKNLWSVFCIRPNSNEDPTQFDKTEVESQVDALNMLSFAKRSTPFFIESLTHFEFLSIYQALFSEYAFDRSQTEKDQCKTIKFLGDWSDTDMLVGSTKIFLSYPLWSQFEEELRVLEKIEQKSKKLSGSYTGPLEDQIEQSRIPMRTGTPLDPSALPSMTNISELDNRYPLTANSPQNHFMSTESFLNSQYAESRFGESDNGFSLNREEELRKNLVMNDDNTAGENSKSMTAGRKRWLCFVWALTFWIPDFCLIKCGRMKRKDVRVAWREKVALCSLILLGCAFVIWFLVFFADLICPSQKVYSENELASHNSDTDGYISIRGEVFKLSDFASHHYPGVVSIGSVLQYVGKDVTNLFPVQVSDLCEGASPYVSLDYTHAFPDNNSQYHDFRYNTGNYRPNWYYDQLTMLRNNYKVGNMGYDVKGIKDQASGAYKINGQSMNRNWAIINDHIYDLTPYIIGGRYISAPPNEVAPSNISTDFLNTNVVNLFWQNSGMDITSKFYNLSLTDVEKERELVCLRNLYYVGLVDVRNSARCQFSTYFMLIITVLLCAIVFFKFAASIRFTQARMPEESDKFVICQVTCYTEDEQSLKKTIDSLACLRYDDKRKLILVICDGMIVGSGNDRPTPRIVLDILGVDPNIDPKPLSFVSVGEGLKKHNRAKLYSGLYEIRGHVVPFLVVVKVGAPNERQKPGNRGKRDSQLVLMEFLNRVQFDAPMNPMQLEMYHQMRNVIGISPEMYDYILMVDADTEVMPMGMSYLVSSMAHDSKIIGLCGETTLSNEKDTWVTMIQVYEYFISHHMIKSFESLFSTVSCLPGCFTMYRIRTVDGKRPLFVSNEIIQDYSVNVVDTLHKKNLLYLGEDRYLTTLLLKHFPSYKTKFNPDAQCKTNAPDTWSVLVSQRRRWINSTVHNLGELAFLDQLCGFCCFSMRFVVMLDLISTLVQPALLAYLGVLIWKLATATNGIPYITIITLGCTYGLQMFIFILHKRWEYIAWFIISILALPVFSFYIPLYSYWHFDDFSWGNTRIVVGEKGKKKTIHDEGEFDPRSIPLMRWSEYEPSRVADDVRSERMSQNAYQASVHSNAMPPMYSNPSMIYPGYFMGHPYFSAGYYNGYPYYMNTAQSVSGYSMNGPSISPTMMRYSFNGLNCSQPVNTDNKSNDSINESISPSMTKSQHPQKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MTY0</accession>
    <name>A0A1C7MTY0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Peptidase A2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">A0J61_11606</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01002244">
        <property type="protein sequence ID" value="OBZ80345.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MTY0"/>
    <dbReference type="InParanoid" id="A0A1C7MTY0"/>
    <dbReference type="OrthoDB" id="2216358at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004190">
        <property type="term" value="F:aspartic-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00303">
        <property type="entry name" value="retropepsin_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.70.10">
        <property type="entry name" value="Acid Proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001995">
        <property type="entry name" value="Peptidase_A2_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021109">
        <property type="entry name" value="Peptidase_aspartic_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13650">
        <property type="entry name" value="Asp_protease_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50630">
        <property type="entry name" value="Acid proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50175">
        <property type="entry name" value="ASP_PROT_RETROV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase A2" evidence="3">
        <location>
            <begin position="292"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="326"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="347"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OBZ80345.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="347" mass="38564" checksum="7AB52D8A33A9867F" modified="2016-11-30" version="1" fragment="single">MSNYQMLVHISDYLPERVRDWILNEPNLTTRTKIKSELIQAFGMPPKEHRLLLLKQMQALLQNKTASREFRIYFQTAINKFPEDMRPDAEDLRAIYLMVMSPNLKDLVAPNAHKLTTWVEINQTAEALERSLYMDPANSLACEYERLTLQASEEPSGTPAATVRDDPMQVDVIRQKPVRNSSSTPHQQDPMRRWTADHKPICGHCHKIGHLTKKCRLRNKVNAVSSQDPQPSVNAMSQQSQATYAAVPIENDPLGRTQPTVNNIGLSRSSSPIVSTKVRTPMVATTLQGHLVKALLNTGADISVIRTSLAEKLGLSPDPSKATTFTIADNSNTSSRGTASVVSMVGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MU16</accession>
    <name>A0A1C7MU16_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Mitochondrial outer membrane protein iml2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">iml2_0</name>
        <name evidence="3" type="ORF">A0J61_11694</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01002356">
        <property type="protein sequence ID" value="OBZ80257.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MU16"/>
    <dbReference type="InParanoid" id="A0A1C7MU16"/>
    <dbReference type="OrthoDB" id="2154985at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005741">
        <property type="term" value="C:mitochondrial outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019412">
        <property type="entry name" value="IML2/TPR_39"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31859">
        <property type="entry name" value="TETRATRICOPEPTIDE REPEAT PROTEIN 39 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31859:SF1">
        <property type="entry name" value="TETRATRICOPEPTIDE REPEAT PROTEIN 39C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10300">
        <property type="entry name" value="Iml2-TPR_39"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="96"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="152"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="16"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="29"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="364"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ80257.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="364" mass="41460" checksum="D8735B60A9759211" modified="2016-11-30" version="1" fragment="single">MFESITGQKASEYAHQLKKTPHQTKQRASFTSLESSQSRSSSWTDKRTSMLHLFSDTIDVPNTKTPSLMLADTTTKPRPISTSDDPLDLIETSFSLIDTAVGSGIFFGIGLFSLIFSLLPPRVNKILNTLGFHSSRPFALHLLLKSFKSHGLYSSLSALSLLAYYTNLSLFIHPKLLPKSLSLDTARQILDRMKITFPQGKIWKLLEGKLCKMEGKTRRGVEILRDARRRENARVDLIISSSTYHYQQQKTNKKKSGSASGCSELAQLQALAVYEMGWGQIFLGDFFQAAETFFRLESMNNWSRAFYHYIATCCMFADEEYDKSALEFMQIPSILKRKRQLGGRLLPNEIFAERKIKHWRSKNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MUL7</accession>
    <name>A0A1C7MUL7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_11407</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01002000">
        <property type="protein sequence ID" value="OBZ80543.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MUL7"/>
    <dbReference type="InParanoid" id="A0A1C7MUL7"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ80543.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="99" mass="10996" checksum="A73732CB1BD6C7B7" modified="2016-11-30" version="1">MFSSFASQNSSQLFKCECSACQLSIPDGYTFIKKRTYNDHQKRDALKKLKTEVPSSSLTTIPANSTTDATNVEEVVTSIDCQAANESYPIEDIDQEGNY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MUV9</accession>
    <name>A0A1C7MUV9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_11276</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001858">
        <property type="protein sequence ID" value="OBZ80675.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MUV9"/>
    <dbReference type="InParanoid" id="A0A1C7MUV9"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017956">
        <property type="entry name" value="AT_hook_DNA-bd_motif"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00929">
        <property type="entry name" value="ATHOOK"/>
    </dbReference>
    <dbReference type="SMART" id="SM00384">
        <property type="entry name" value="AT_hook"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="51"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ80675.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="84" mass="9585" checksum="3D06C62FD9FDB052" modified="2016-11-30" version="1">MLSQKRNISPPKASSEKSKKRPRVSSVLVIQPDQDVRKRGRPKKVLDNTIKKPKKTRGRPKKATEEPSSETPVHQFIFQPPDTN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MUW6</accession>
    <name>A0A1C7MUW6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_11266</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001841">
        <property type="protein sequence ID" value="OBZ80685.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7MUW6"/>
    <dbReference type="InParanoid" id="A0A1C7MUW6"/>
    <dbReference type="OrthoDB" id="2286663at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ80685.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="150" mass="17377" checksum="5D5735C47653564C" modified="2016-11-30" version="1">MKPLYEKHFPAFQVERLGKVTEKGLKKGDIAEWFYGPDCGQLVADTYGVPVCLYPFAESELPGINPPLTFLPLNLPKTKSKPVAIHIQNGHNLHWYAISLGVNQNNLPSVYHYFFMNDEKIEDYDKXWNKWRQFSKRKSPKKSPEIITLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MVU5</accession>
    <name>A0A1C7MVU5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">60S ribosomal protein L36</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">rpl36a_1</name>
        <name evidence="5" type="ORF">A0J61_10926</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the eukaryotic ribosomal protein eL36 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001517">
        <property type="protein sequence ID" value="OBZ81025.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MVU5"/>
    <dbReference type="FunCoup" id="A0A1C7MVU5">
        <property type="interactions" value="407"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7MVU5"/>
    <dbReference type="InParanoid" id="A0A1C7MVU5"/>
    <dbReference type="OrthoDB" id="9616667at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.1760:FF:000003">
        <property type="entry name" value="60S ribosomal protein L36"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.1760">
        <property type="entry name" value="60S ribosomal protein L36"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000509">
        <property type="entry name" value="Ribosomal_eL36"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038097">
        <property type="entry name" value="Ribosomal_eL36_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10114">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L36"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01158">
        <property type="entry name" value="Ribosomal_L36e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01190">
        <property type="entry name" value="RIBOSOMAL_L36E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 5" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006509"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000665"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OBZ81025.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="99" mass="10885" checksum="183B9A42DABC893D" modified="2016-11-30" version="1">MAASGIAVGINKGHIVTRRELKAKPSNKIGAASKRATFVRGVIREVAGFAPYERRLMELIKNSKDKRAKKLCKAKLGTFLRAKKKIEELTAAVAASRRH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-06-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MWG6</accession>
    <name>A0A1C7MWG6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_11182</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001753">
        <property type="protein sequence ID" value="OBZ80769.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MWG6"/>
    <dbReference type="InParanoid" id="A0A1C7MWG6"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ80769.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="69" mass="7857" checksum="16A07ED90B820F67" modified="2016-11-30" version="1">MVTSLFNRTSNANRNDSQANEVGYIFNLSCVEVRNKAERNALVEDITQERNEELILEPAEDLVEDLAED</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MWZ3</accession>
    <name>A0A1C7MWZ3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">3'-5' exonuclease domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">A0J61_10547</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001229">
        <property type="protein sequence ID" value="OBZ81405.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MWZ3"/>
    <dbReference type="InParanoid" id="A0A1C7MWZ3"/>
    <dbReference type="OrthoDB" id="1920326at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008408">
        <property type="term" value="F:3'-5' exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051132">
        <property type="entry name" value="3-5_Exonuclease_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13620:SF109">
        <property type="entry name" value="3'-5' EXONUCLEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13620">
        <property type="entry name" value="3-5 EXONUCLEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1" id="KW-0540">Nuclease</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OBZ81405.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="157" mass="17576" checksum="F48AF46FB90AA46A" modified="2016-11-30" version="1">MYDTGGELELSLFCFNRNAISSNRKSLSDIYSTVLGFHLPKNNDVRLSNWEALELSDQQKHYAALDAYGAIVVYKSVKYMKLVNEPVSRSTCSGTFVGIYPENSSKLIAATVFGHICNPDDDKSYFCSVPSNISVSTERNNLALIKFVDVKRPDYIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MXB7</accession>
    <name>A0A1C7MXB7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">A0J61_10882</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001480">
        <property type="protein sequence ID" value="OBZ81069.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MXB7"/>
    <dbReference type="STRING" id="101091.A0A1C7MXB7"/>
    <dbReference type="InParanoid" id="A0A1C7MXB7"/>
    <dbReference type="OrthoDB" id="2290773at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046700">
        <property type="entry name" value="DUF6570"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025476">
        <property type="entry name" value="Helitron_helicase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20209">
        <property type="entry name" value="DUF6570"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14214">
        <property type="entry name" value="Helitron_like_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF6570" evidence="3">
        <location>
            <begin position="239"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="domain" description="Helitron helicase-like" evidence="2">
        <location>
            <begin position="544"/>
            <end position="681"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="41"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="61"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="74"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="757"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF14214"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF20209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OBZ81069.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="757" mass="87340" checksum="8205EE0FB0C54880" modified="2016-11-30" version="1" fragment="single">MSENPTESSSTHQRRSQRVRVPNQDPDFVYATNFTQGRQNRVIFISEETNEATRRPRKRKEPSSLEQRRQNARERKRASRLRRAQSESLAIENNENMLALEESEVGENSVQRPLRIESVTLADTTTGELPVNDLANEERRLEERRHLAAERQREHRARIHNSLREEKIEKKYQAMIKEGPTVVCVCCGGLWFPVQTKSVTKAFLLSREAIEEFIERVFNVEVTDQLEEFCDNCSLFVKKKKVPHLCLSNGLKLPEIPEEIKRLNRIEERLVAAKHVFQSIYTVFGLRGQYKSKGAIVNVPVSVDKTVSCIPRLPEDTNIIQVKLKRRLDQANSYMSGNVNISKVWAAAVVLKDTDAYKKHNVTIRDSLEIFNELSILTSEQNLMDKLVEALADIDINDDDAMDEIANPGGAETLYSGIEIPTMPIQIDTEGIQIAPAEGSRPMRLLLDKDVEYLAFPTLFGGAIMEPIYEEKPISYASIVKSWARTHDRRMVKRIDFLLFMDRKRQLLNLASHVTTVMRMSKARLENPLRVHNILENDGLSDILKKDQAFQVLQKVRSSPAYWKKERSNVMSMVRQLGVSTLFVTLSAAEAKWPELLVILKKVVNNEVLTENEANELSREEKARLIQSDSTTCARYFDRRMRILKNTWKPPYGPFGNYAIKDYYYRIEFQHRGLPHAHMLLWLDNAPELEQDINDPFGRGVNRQSVAKLIDSMMTCDVDDANNDEAFKELVLSRQVHRHTRSCFRYCKNDKTKCRFN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-06-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MXM6</accession>
    <name>A0A1C7MXM6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_10369</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001139">
        <property type="protein sequence ID" value="OBZ81583.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MXM6"/>
    <dbReference type="InParanoid" id="A0A1C7MXM6"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ81583.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="115" mass="12781" checksum="3572DFECE63CC082" modified="2016-11-30" version="1">MALDMSVDSNRGLFTDKDSACDNGRAIHQRIEFSLQRSGESLEVETINHVKATSHSDPVTTSLLQASTGHNSQREGTVVDVSLFQPMTFEKTVLHDTLIYSVLRWRAFDPVISTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MY10</accession>
    <name>A0A1C7MY10_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">glucose-6-phosphate dehydrogenase (NADP(+))</fullName>
            <ecNumber evidence="2">1.1.1.49</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">gsdA_1</name>
        <name evidence="8" type="ORF">A0J61_10260</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Carbohydrate degradation; pentose phosphate pathway; D-ribulose 5-phosphate from D-glucose 6-phosphate (oxidative stage): step 1/3.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.49" evidence="2"/>
    <dbReference type="EMBL" id="LUGH01001090">
        <property type="protein sequence ID" value="OBZ81692.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MY10"/>
    <dbReference type="STRING" id="101091.A0A1C7MY10"/>
    <dbReference type="InParanoid" id="A0A1C7MY10"/>
    <dbReference type="OrthoDB" id="60984at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004345">
        <property type="term" value="F:glucose-6-phosphate dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006006">
        <property type="term" value="P:glucose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009051">
        <property type="term" value="P:pentose-phosphate shunt, oxidative branch"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001282">
        <property type="entry name" value="G6P_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022674">
        <property type="entry name" value="G6P_DH_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23429:SF0">
        <property type="entry name" value="GLUCOSE-6-PHOSPHATE 1-DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23429">
        <property type="entry name" value="GLUCOSE-6-PHOSPHATE 1-DEHYDROGENASE G6PD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00479">
        <property type="entry name" value="G6PD_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="3" id="KW-0313">Glucose metabolism</keyword>
    <keyword evidence="4" id="KW-0521">NADP</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glucose-6-phosphate dehydrogenase NAD-binding" evidence="7">
        <location>
            <begin position="23"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="179"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004937"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022526"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OBZ81692.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="179" mass="20292" checksum="8EDB56DF857B1217" modified="2016-11-30" version="1" fragment="single">MTSAIQILRDQVAKELQGSVTIVVLGASGDLAKKKTYPALFGLYRNGFLPENTHIVGYARTKMEHDDYLKRITQYIKVNDAEKLEEFKKITSYVSGHYDDDASYQNLDKYIQESESKRGIDVKNRNRVFYMALPPSVFIPVAKGLKRNVYSKEAINRLVVEKPFGMDSESSAHLAHELG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MY97</accession>
    <name>A0A1C7MY97_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Methylsterol monooxygenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">ERG25</name>
        <name evidence="7" type="ORF">A0J61_10179</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001061">
        <property type="protein sequence ID" value="OBZ81772.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MY97"/>
    <dbReference type="FunCoup" id="A0A1C7MY97">
        <property type="interactions" value="158"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7MY97"/>
    <dbReference type="InParanoid" id="A0A1C7MY97"/>
    <dbReference type="OrthoDB" id="1658724at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000254">
        <property type="term" value="F:C-4 methylsterol oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006696">
        <property type="term" value="P:ergosterol biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006694">
        <property type="entry name" value="Fatty_acid_hydroxylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050307">
        <property type="entry name" value="Sterol_Desaturase_Related"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11863">
        <property type="entry name" value="STEROL DESATURASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04116">
        <property type="entry name" value="FA_hydroxylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="26"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="domain" description="Fatty acid hydroxylase" evidence="6">
        <location>
            <begin position="122"/>
            <end position="267"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF04116"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OBZ81772.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="288" mass="34620" checksum="A7C89920825724A3" modified="2016-11-30" version="1">MNTTVEDYQLNWLETRWEDLYKDRNALLVTGLLAFTMHEIVYFGRFIPFLICDYIPYFKQYKIQPDKQNKSEDVWKCTKLVLYQHFFYEGPLIFLFHPMATFLGMNVSAPFPEWKYIAIQIAIFFVFEDAYHYAVHRLMHWPPLYKKIHKVHHEYAAPFGIAAEYAHPLETSILGLGTIGGPLLYHTVETLYFHQGRNWQLHLFTMLTWIVCRLFQAIDCHSGYDFPWSLRHIIPFWAGADHHDYHHMAFVGNYASSFRWWDWLLGTDVKYRAYRKRQAEMKRKLKEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MYV8</accession>
    <name>A0A1C7MYV8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Protein CobW</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">cobW</name>
        <name evidence="8" type="ORF">A0J61_10362</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>GTP + H2O = GDP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:19669"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58189"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="5">
            <dbReference type="Rhea" id="RHEA:19670"/>
        </physiologicalReaction>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001136">
        <property type="protein sequence ID" value="OBZ81589.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MYV8"/>
    <dbReference type="STRING" id="101091.A0A1C7MYV8"/>
    <dbReference type="InParanoid" id="A0A1C7MYV8"/>
    <dbReference type="OrthoDB" id="272672at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd03112">
        <property type="entry name" value="CobW-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1220.10">
        <property type="entry name" value="CobW-like, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036627">
        <property type="entry name" value="CobW-likC_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011629">
        <property type="entry name" value="CobW-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003495">
        <property type="entry name" value="CobW/HypB/UreG_nucleotide-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051316">
        <property type="entry name" value="Zinc-reg_GTPase_activator"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13748:SF62">
        <property type="entry name" value="COBW DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13748">
        <property type="entry name" value="COBW-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02492">
        <property type="entry name" value="cobW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07683">
        <property type="entry name" value="CobW_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90002">
        <property type="entry name" value="Hypothetical protein YjiA, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0143">Chaperone</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CobW/HypB/UreG nucleotide-binding" evidence="6">
        <location>
            <begin position="9"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="domain" description="CobW C-terminal" evidence="7">
        <location>
            <begin position="238"/>
            <end position="316"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00034320"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00049117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF02492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF07683"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OBZ81589.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="336" mass="37857" checksum="C56DD1FAF15091CB" modified="2016-11-30" version="1">MASTAKPLPITVFTGFLGSGKTTQILSLLQRVPKDYKVCLLKNEFGDIAVDSQLAKETNVGVQEMVNGCMCCVLVGQMKLALQELKDQYNPDRIIIETSGSAFPAPIAWQIREMEPEGFVLDSIITVVDCENFKGYEDTSYTAKLQAQYTDVILLNKHELVNERQLDDVLDHVNVLNTDTPKVKCDKNGVSPDLVFGLDTQLFKVGYDKHKSLEESVFDPHHQENEVDLIQILQSVNDNRLTLAQFESFLKTMPKDDIYRIKGFIRLQDQPLSIVNHAFGRWTLTAVENEDTLENTKDVQIKITVMGQDLRMYIEKVKALLNGGDGDVKLTPAHRH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N1D5</accession>
    <name>A0A1C7N1D5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Cysteine-rich transmembrane CYSTM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_09045</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000761">
        <property type="protein sequence ID" value="OBZ82903.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N1D5"/>
    <dbReference type="InParanoid" id="A0A1C7N1D5"/>
    <dbReference type="OrthoDB" id="2259212at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ82903.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="74" mass="8201" checksum="B30EBBADEFAE6EFD" modified="2016-11-30" version="1">MTQEIKSKRKSHLSDQHHVLDATSFSKKAQFYHPTPAPDTVVVHSVPKKTDDACCWGCAAALCLCFGIKECCNH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N1U2</accession>
    <name>A0A1C7N1U2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">BZIP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">A0J61_08878</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000727">
        <property type="protein sequence ID" value="OBZ83073.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N1U2"/>
    <dbReference type="InParanoid" id="A0A1C7N1U2"/>
    <dbReference type="OrthoDB" id="1939598at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd14705">
        <property type="entry name" value="bZIP_Zip1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.170">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004827">
        <property type="entry name" value="bZIP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046347">
        <property type="entry name" value="bZIP_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07716">
        <property type="entry name" value="bZIP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00338">
        <property type="entry name" value="BRLZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57959">
        <property type="entry name" value="Leucine zipper domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50217">
        <property type="entry name" value="BZIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00036">
        <property type="entry name" value="BZIP_BASIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BZIP" evidence="3">
        <location>
            <begin position="141"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="47"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="169"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="85"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="105"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="121"/>
            <end position="132"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OBZ83073.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="278" mass="31589" checksum="568A96D8579DC57E" modified="2016-11-30" version="1">MVLPASKSDSYSNPLGKPMSISSILTMPHINVSSSSLTHKVYHKEAMERRASAPSHPYHHPQKYPVVNFARSPPMTPEERLFETSIPSSPSSSISSISSQKPPFRSTQTYNQSNSRQESSFEGEDEDIDDADMNNPPLTLQERRLRNKAASAKYRQKKNQQQNEMRLMIGRLSEQNAVLERQLQELRLENDRLKTTTDKLRGKMXAKKILKKWIDRQTSDGNEDKKSFVHNQKEAQMNYSYSHTALGYSTNNGNMNTVIASILSSQSEDEQLDNIVSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N265</accession>
    <name>A0A1C7N265_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_08825</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000717">
        <property type="protein sequence ID" value="OBZ83127.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N265"/>
    <dbReference type="InParanoid" id="A0A1C7N265"/>
    <dbReference type="OrthoDB" id="2280528at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="87"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="22"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="34"/>
            <end position="45"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ83127.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="130" mass="14967" checksum="C0B21D8A6A3E717C" modified="2016-11-30" version="1">MHVLFNRLLSSKKSRDEKKRLSTSTTSSSSSSSMKKKYWIKKKQNRTASVDHEQHQKQQDLLTQCISNALFVDVNPSQVEPGIRFQEHAQEEEKKKPRTRKLSLPPQPAHMGYLASIPEAEDSQVTLYKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N2G3</accession>
    <name>A0A1C7N2G3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Beta-chimaerin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">Chn2_1</name>
        <name evidence="6" type="ORF">A0J61_08758</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000705">
        <property type="protein sequence ID" value="OBZ83191.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N2G3"/>
    <dbReference type="FunCoup" id="A0A1C7N2G3">
        <property type="interactions" value="278"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N2G3"/>
    <dbReference type="InParanoid" id="A0A1C7N2G3"/>
    <dbReference type="OrthoDB" id="79452at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.60">
        <property type="entry name" value="Arfaptin homology (AH) domain/BAR domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.555.10">
        <property type="entry name" value="Rho GTPase activation protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027267">
        <property type="entry name" value="AH/BAR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031160">
        <property type="entry name" value="F_BAR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001060">
        <property type="entry name" value="FCH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050729">
        <property type="entry name" value="Rho-GAP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008936">
        <property type="entry name" value="Rho_GTPase_activation_prot"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000198">
        <property type="entry name" value="RhoGAP_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23176:SF134">
        <property type="entry name" value="RHO-TYPE GTPASE-ACTIVATING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23176">
        <property type="entry name" value="RHO/RAC/CDC GTPASE-ACTIVATING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00611">
        <property type="entry name" value="FCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00620">
        <property type="entry name" value="RhoGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00055">
        <property type="entry name" value="FCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00324">
        <property type="entry name" value="RhoGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103657">
        <property type="entry name" value="BAR/IMD domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48350">
        <property type="entry name" value="GTPase activation domain, GAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51741">
        <property type="entry name" value="F_BAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50238">
        <property type="entry name" value="RHOGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0343">GTPase activation</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-BAR" evidence="5">
        <location>
            <begin position="40"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="domain" description="Rho-GAP" evidence="4">
        <location>
            <begin position="358"/>
            <end position="564"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="8"/>
            <end position="32"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022468"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50238"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OBZ83191.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="569" mass="64490" checksum="3EACB1721A53CBE1" modified="2016-11-30" version="1">MLTVEENAPQTFPDSNISDNSMDMASSPKPLTTTLTEADSEVTGKLVEVEGGFQCLLDKVKQDMQATKDVITFLEKRAAIEKEYGKQLMKLSQSMHETYEKAHTKKSSYGTVWTRFLKVHETIGEQRVKFAGDISEVADDLQIVYKDTEKNRKASKEQGNRHDKNRLDSEIALEKSKVKYESLSEEWEKAILTKNTNESEYMPKKSGLFKSNKTPAQLQKIVDDSCAKANQAQTVYKNQLNTTNITRQGYFQTQLPSDIAHLKSVSDECCGATRYQLARYSYFFEVAVTADGNALDNDQGTGLRSLCEKINYDQDMAIIVNEFGADAPRLKKADIPYKEFPMSQVALSILRPNPVFSVDLTKLMQRDGHEVPLFLTKCVEAIESSGLKTEGLYRVSGTGTHIQRLKNSFDRDCAAVDLSTDEGTADINNVTSLLKLWFRELPDPLFPRSSYQHFMNAAKIENERMRVLGLHTIINDLPDAHYATLKYLMCHLDKVQKYQEFNKMTTGNLSTIFGITLMGGETSSNQSSISSQEQCLQQEEQRLADTHWHVRVVKTILENYRLIFEPDEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N2H3</accession>
    <name>A0A1C7N2H3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_08696</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000694">
        <property type="protein sequence ID" value="OBZ83257.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N2H3"/>
    <dbReference type="STRING" id="101091.A0A1C7N2H3"/>
    <dbReference type="InParanoid" id="A0A1C7N2H3"/>
    <dbReference type="OrthoDB" id="2379842at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ83257.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="99" mass="11379" checksum="A1B50224098D1C28" modified="2016-11-30" version="1">MLSVMSKEFENGMSYEDFYRSSFGMTTDEVKMTITCGIDLHKKEDEVTHYDRHRKAKTAGMAFWFDSIDCMQVLADAYSRPVCYHPDSGSKSQLDIALM</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N2H9</accession>
    <name>A0A1C7N2H9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_09056</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000763">
        <property type="protein sequence ID" value="OBZ82896.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N2H9"/>
    <dbReference type="InParanoid" id="A0A1C7N2H9"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ82896.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="145" mass="16061" checksum="5D74B2CC29917DB3" modified="2016-11-30" version="1">MNERQFNASPIVFPSVSPKLSSTPSKKLPSNEWHEIGIDLPHKRQTILTNLEEPEVGLSSILSTPSAYTLASQRTSQSSQTPSVQSTMPDYLDINVFQDKTPHAQFKLILLKICTTLFGPLAQIISMRFAIVVLIIEGPWGIELA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N2W1</accession>
    <name>A0A1C7N2W1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">CLIP1 zinc knuckle domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">A0J61_08590</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000677">
        <property type="protein sequence ID" value="OBZ83358.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N2W1"/>
    <dbReference type="STRING" id="101091.A0A1C7N2W1"/>
    <dbReference type="InParanoid" id="A0A1C7N2W1"/>
    <dbReference type="OrthoDB" id="2130750at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032108">
        <property type="entry name" value="CLIP1_ZNF"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16641">
        <property type="entry name" value="CLIP1_ZNF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="3" id="KW-0493">Microtubule</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CLIP1 zinc knuckle" evidence="7">
        <location>
            <begin position="601"/>
            <end position="616"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="176"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="498"/>
            <end position="518"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="52"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="85"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="6">
        <location>
            <begin position="100"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="190"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="498"/>
            <end position="517"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF16641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OBZ83358.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="650" mass="73932" checksum="353A854883A3BA73" modified="2016-11-30" version="1">MKPSNSSTTSNGSLKKQSILRSSAIPATSNMKRPPSVTRPASTTRPPSVARSPSTTQSSSSPPLSSSAPTTSFVESPVLPPTPSQKPTLTPSTQTKKPQTPTPPPPPPATITMDEHQETTNQLYEMLEKVQRERDQLLAQMKTKETAWERLVSSRESLSLQVQENESRCQRLSRELESAQNEVEQLRNGLAERDASLAKNQRDEEKTSQDQKRIERLEALVRDLQSQLQASKDEQLQLSRDHAGILEQVRREVSSNEAMTASLEKECEELRRTSLEAIRAYESSLLEINEKHGAELKQREQQIQQLEYTIADLRHKQSTLFDDDEQDIDTRLNEMRHASMGSASTAEADQRHRLEEQLELAMAELDHERHSIQTLQQEMDQLKLELGQARQQSLSVEQKYESLQAEFEKELNDKKRLIEEADNAFEAQARAEDEHYQMKLSKMALEKEFNELSEAHKQLEHDYSHLMDDMLALEKQDLKNPMDPAVTPDTARLQEKVQQLERENESHRHSLSAEKKQVSQLSKDLAELESLVESRVFGEADLEEQLNDERKKVIALQKELDAIKNRTSIQTKDVLASPMTLGTPSPTLSPNQKHQDKTPSKYCELCESDGHTIMECKSELSLSESKLFCENCDDFGDHVTEECPNQDETF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N3C3</accession>
    <name>A0A1C7N3C3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Calcineurin-like phosphoesterase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_08350</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000634">
        <property type="protein sequence ID" value="OBZ83600.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N3C3"/>
    <dbReference type="FunCoup" id="A0A1C7N3C3">
        <property type="interactions" value="5"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N3C3"/>
    <dbReference type="InParanoid" id="A0A1C7N3C3"/>
    <dbReference type="OrthoDB" id="5976022at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46546">
        <property type="entry name" value="SHEWANELLA-LIKE PROTEIN PHOSPHATASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46546:SF4">
        <property type="entry name" value="SHEWANELLA-LIKE PROTEIN PHOSPHATASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="Metallo-dependent phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008889457" description="Calcineurin-like phosphoesterase domain-containing protein" evidence="1">
        <location>
            <begin position="24"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="domain" description="Calcineurin-like phosphoesterase" evidence="2">
        <location>
            <begin position="30"/>
            <end position="245"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ83600.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="314" mass="34490" checksum="2D7BAFF9AA03BDBF" modified="2016-11-30" version="1">MVRIATTLASLAYAALTGWSVSADIEADRRIVALGDLHGDLPNTLEILKFSHLIDDDHHWIGGDAIFVQTGDVVDRGTDTIKLYELIQNLRDEAPLQGGMVIPLLGNHEIMNLIGDWRYVYPGEPETFGGLEARRKAFEHDGFIGEYLTMLNMTTKVGSTVFCHGGITPYFGELGIDWINNQTHATIVPFMKSFGQHGDPHGIYGAEGPTWYRGYALDDEDIVCNLLDQALDYMEANRMVVGHTVQHDGAIHTRCGGKVVLIDIGISSAYGGQKGALEIRGNKAVALYAHHNETLPTPAPYKPKSKSPIVHEEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N3H1</accession>
    <name>A0A1C7N3H1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Arrestin-like N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_08763</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000706">
        <property type="protein sequence ID" value="OBZ83186.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N3H1"/>
    <dbReference type="STRING" id="101091.A0A1C7N3H1"/>
    <dbReference type="InParanoid" id="A0A1C7N3H1"/>
    <dbReference type="OrthoDB" id="2225514at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.640">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014752">
        <property type="entry name" value="Arrestin-like_C"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ83186.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="229" mass="25694" checksum="27C0FE978158E955" modified="2016-11-30" version="1">MEYISGDTIDAIICIANQEAASSSSIITPSFKFDYSITANLYQVCHFHHSQRTAPPQLVGTQSYSLDLNENIHEEETQHHISLKLESYLPPSFDFSKILSFSYKLRVKVYVKRARTSLSSAVSQQDSKMLKEAMALPWPTSTMLIFETPIVIGTLGQGIRTRDELQTYTSFNGENNVLPTPKFIQHLEHEDELPKYEPIRLPEYEENAEDQAAVGSVISSSSASSITVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N3I9</accession>
    <name>A0A1C7N3I9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_08266</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000621">
        <property type="protein sequence ID" value="OBZ83682.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N3I9"/>
    <dbReference type="InParanoid" id="A0A1C7N3I9"/>
    <dbReference type="OrthoDB" id="2563506at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024368">
        <property type="entry name" value="Ecl1/2/3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12855">
        <property type="entry name" value="Ecl1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ83682.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="92" mass="10899" checksum="DCA85A5FB3AF5227" modified="2016-11-30" version="1">MDLSWCIICDSRIPDEWMMANNSLYCSQECRQKDDVKTETLKPWMTRKSTARHHLYRTVAPTTAYPWVPLYRKRRGSAVLRCIVQPSSHLIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N3U5</accession>
    <name>A0A1C7N3U5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">PhoD-like phosphatase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_08137</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000600">
        <property type="protein sequence ID" value="OBZ83815.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N3U5"/>
    <dbReference type="InParanoid" id="A0A1C7N3U5"/>
    <dbReference type="OrthoDB" id="9999821at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07389">
        <property type="entry name" value="MPP_PhoD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.70">
        <property type="entry name" value="PhoD-like phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018946">
        <property type="entry name" value="PhoD-like_MPP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038607">
        <property type="entry name" value="PhoD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043904">
        <property type="entry name" value="PhoD_2-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46689">
        <property type="entry name" value="MEMBRANE PROTEIN, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46689:SF1">
        <property type="entry name" value="PHOD-LIKE PHOSPHATASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19050">
        <property type="entry name" value="PhoD_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PhoD-like phosphatase" evidence="1">
        <location>
            <begin position="151"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="domain" description="PhoD-like phosphatase" evidence="1">
        <location>
            <begin position="412"/>
            <end position="578"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF19050"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ83815.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="674" mass="77526" checksum="FD61805240B9F041" modified="2016-11-30" version="1">MQGYGAPPQNQSSFHGFSESFSQLQIGERWNNLQSHFHHDDRPGEVVCGPLLRYIDINYRTRIWRGSILVVSTDHHPPPVEIQLTDASRRLINTLQPQAEKLDSYRRQYHFWRYEVRIPLLDGPQVATYRTAANNWAEQSFQMHLPSFYESMRFMFYSCNGFSDIPQEVKDKFGEKTAPLWQDVLDRHEVMPFHVLLGGGDQLYQDRLIKEEFMKPWVAEKDPAKRLAMKLPDFMKEGFEEFFFWNYCKNFGFKENPVVAKAFATIPSMNMWDDHDIIDGYGSYPADMQNAECFQVLFXNATRFYYLFQHHTTVELAPQHGLFRGTLETCNSIISTLGPDIGYVALDCRGERTKHDICKSTTYDSLFALLPTQLPPTVKHLFIQTGVPLIYPRLTLFENLMDGAAGFNLATIAGKTGALGDMISGQLNVWNGDPELLDDMNDHWTAGVHEAERKMFIERLQQYARERSIRVSFLGGDVHCCGAGKMYSKDMKEKEEGDPFFMVQIISSAIVNVPPPQALLTVLNQNSSYITFNGNTEERMYNIFKKSPNGNNRQNKKLMGMRNYCAGYYDEQTGKVNFWIQAEKEVGVKGTMGYLVDVPKLLFGQAGYHLSHQNKRQVLNDLSQPPPQHQNFFQGHSEHFHLGHHREENGEHDHSAFHRLHSKIGGFVMPRSTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-06-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N436</accession>
    <name>A0A1C7N436_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_08107</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000595">
        <property type="protein sequence ID" value="OBZ83840.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N436"/>
    <dbReference type="InParanoid" id="A0A1C7N436"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008889463" evidence="1">
        <location>
            <begin position="20"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ83840.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="61" mass="7073" checksum="F79CE6705D6CA60E" modified="2016-11-30" version="1">MQFHLLILIIGGQTVYVKEERTTRAYVTAFHNKTLGLRGTSFFEINRKDGTSQQCVRAWLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N487</accession>
    <name>A0A1C7N487_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Phosphotransferase</fullName>
            <ecNumber evidence="6">2.7.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">hxk1_3</name>
        <name evidence="9" type="ORF">A0J61_09826</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the hexokinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.-" evidence="6"/>
    <dbReference type="EMBL" id="LUGH01000948">
        <property type="protein sequence ID" value="OBZ82124.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N487"/>
    <dbReference type="STRING" id="101091.A0A1C7N487"/>
    <dbReference type="InParanoid" id="A0A1C7N487"/>
    <dbReference type="OrthoDB" id="419537at2759"/>
    <dbReference type="UniPathway" id="UPA00109">
        <property type="reaction ID" value="UER00180"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005536">
        <property type="term" value="F:D-glucose binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008865">
        <property type="term" value="F:fructokinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004340">
        <property type="term" value="F:glucokinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019158">
        <property type="term" value="F:mannokinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006006">
        <property type="term" value="P:glucose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006096">
        <property type="term" value="P:glycolytic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001678">
        <property type="term" value="P:intracellular glucose homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006013">
        <property type="term" value="P:mannose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.367.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001312">
        <property type="entry name" value="Hexokinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022673">
        <property type="entry name" value="Hexokinase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022672">
        <property type="entry name" value="Hexokinase_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19443">
        <property type="entry name" value="HEXOKINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19443:SF24">
        <property type="entry name" value="PHOSPHOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00349">
        <property type="entry name" value="Hexokinase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03727">
        <property type="entry name" value="Hexokinase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00475">
        <property type="entry name" value="HEXOKINASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51748">
        <property type="entry name" value="HEXOKINASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="4 6 9" id="KW-0418">Kinase</keyword>
    <keyword evidence="3 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Hexokinase N-terminal" evidence="7">
        <location>
            <begin position="4"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="domain" description="Hexokinase C-terminal" evidence="8">
        <location>
            <begin position="209"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU362007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00349"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF03727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OBZ82124.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="539" mass="59569" checksum="BFA43742757C0EEC" modified="2016-11-30" version="1" fragment="single">SSFLEKIKLAFELDDTAFESIVNGFKAEYNTGLESASASGLATMIPSYVTTLPTGKETGTYLSLDLGGSTLRVCAVELLGNCNSKVTEIRRHIAPNDPLRTSGATAFFDWIVDTVTELLQRIGHDTVYAEGPLSMGICWSFPVDQTSISDGKILRMGKGFTIGGIEGYDLAGLFEQSFKRRNVNVKVMALLNDTVGTLVAHAYSNPDVRVGFIYGTGVNAAYPEKVRRIIKLRDQQQIYTADTTMLVNTEIDIFGNDTYLPRNKYDKQLDENHSQPNFQLYEKMMSGACIGELVRLSALDLIGEGHLFEGHQPMELDKAMEFGTAVTSDIESHLNNDPKARLDHFKGLLSFKDGYLVSQKDLDIFSKLCVIVSDRAARLAAAAMASLIEQQPELINEAGPIVIGVNGSTYEKYTRMHDRICTSLTRWFGAEVGRRIKVEVATDGGSIGGALIAMLAEKEEKRRLRSTYQTDQSYGIAIDNTKKQPLDLSSKPLNREVAVSTRSPSLFGCLFGWLTPSRTKRRDRSSLIEETVNMKQEKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N4F5</accession>
    <name>A0A1C7N4F5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Candidapepsin-7</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">SAP7_0</name>
        <name evidence="3" type="ORF">A0J61_07970</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase A1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000573">
        <property type="protein sequence ID" value="OBZ83980.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N4F5"/>
    <dbReference type="STRING" id="101091.A0A1C7N4F5"/>
    <dbReference type="InParanoid" id="A0A1C7N4F5"/>
    <dbReference type="OrthoDB" id="771136at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004190">
        <property type="term" value="F:aspartic-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.70.10">
        <property type="entry name" value="Acid Proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001461">
        <property type="entry name" value="Aspartic_peptidase_A1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033121">
        <property type="entry name" value="PEPTIDASE_A1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021109">
        <property type="entry name" value="Peptidase_aspartic_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47966:SF65">
        <property type="entry name" value="ASPARTIC-TYPE ENDOPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47966">
        <property type="entry name" value="BETA-SITE APP-CLEAVING ENZYME, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00026">
        <property type="entry name" value="Asp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50630">
        <property type="entry name" value="Acid proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51767">
        <property type="entry name" value="PEPTIDASE_A1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase A1" evidence="2">
        <location>
            <begin position="1"/>
            <end position="157"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51767"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ83980.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="212" mass="23940" checksum="4A6447E8C49DBF5F" modified="2016-11-30" version="1">MVGSDSIQVRRDHTRDQNLVYSNTFSHARGLIIDTGTTLTYMDHEMAEAIVHRVAYGSVLFDSKSGVYIVDCRTGVDPSRSYSVHFTLSQSQTKLSIPVRDLVLPIGDGLCMFGIAPWMNTGNSAKMKEKGWILVGDSVLRSSYLVFDMKQHQIGFAKAASQTSFRQNYVSLELLPQKQRKEKRMLIEFNLQFPTNEEFKTDKGAKETALDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N4P2</accession>
    <name>A0A1C7N4P2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_07864</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000557">
        <property type="protein sequence ID" value="OBZ84092.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N4P2"/>
    <dbReference type="STRING" id="101091.A0A1C7N4P2"/>
    <dbReference type="InParanoid" id="A0A1C7N4P2"/>
    <dbReference type="OrthoDB" id="190098at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ84092.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="120" mass="14352" checksum="81A2FD9B95EEF34C" modified="2016-11-30" version="1">MYRQFLKAGQAATEGHNKKHIRSLIREGFENPTFARDPEIEIKARNTLRLLQLAGERRGIEFDLVRNLCQLKYFRDRDNLRPPLFNRRIPQQQKALHDQPRKDLELMIEMLNRDLQLCLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N4S0</accession>
    <name>A0A1C7N4S0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Bromodomain and WD repeat-containing protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">Brwd1</name>
        <name evidence="8" type="ORF">A0J61_09638</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000896">
        <property type="protein sequence ID" value="OBZ82314.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N4S0"/>
    <dbReference type="InParanoid" id="A0A1C7N4S0"/>
    <dbReference type="OrthoDB" id="538223at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006325">
        <property type="term" value="P:chromatin organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007010">
        <property type="term" value="P:cytoskeleton organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd04369">
        <property type="entry name" value="Bromodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.920.10">
        <property type="entry name" value="Bromodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052060">
        <property type="entry name" value="Bromo_WD_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001487">
        <property type="entry name" value="Bromodomain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036427">
        <property type="entry name" value="Bromodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057451">
        <property type="entry name" value="BRWD/PHIP_AD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057452">
        <property type="entry name" value="BRWD/PHIP_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16266:SF17">
        <property type="entry name" value="BRWD3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16266">
        <property type="entry name" value="WD REPEAT DOMAIN 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00439">
        <property type="entry name" value="Bromodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25437">
        <property type="entry name" value="BRWD1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25313">
        <property type="entry name" value="BRWD_AD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00503">
        <property type="entry name" value="BROMODOMAIN"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00297">
        <property type="entry name" value="BROMO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47370">
        <property type="entry name" value="Bromodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50014">
        <property type="entry name" value="BROMODOMAIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4" id="KW-0103">Bromodomain</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 5" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="167"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="209"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="394"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="545"/>
            <end position="587"/>
        </location>
    </feature>
    <feature type="domain" description="Bromo" evidence="7">
        <location>
            <begin position="1271"/>
            <end position="1341"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="450"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="745"/>
            <end position="1037"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1359"/>
            <end position="1417"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="456"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="6">
        <location>
            <begin position="758"/>
            <end position="767"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="770"/>
            <end position="779"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="803"/>
            <end position="813"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="908"/>
            <end position="930"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="959"/>
            <end position="970"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="971"/>
            <end position="982"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="990"/>
            <end position="1003"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="1014"/>
            <end position="1024"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="1376"/>
            <end position="1393"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1394"/>
            <end position="1407"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="1408"/>
            <end position="1417"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OBZ82314.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="1417" mass="162834" checksum="418AD51CC0F1F3FD" modified="2016-11-30" version="1">MLWSKLYYLITKFLAAGPCKDAARVLERELDQHRELLPHTITYEGKQVPMTLDRLSKEYPDISNNYLLELLSNLLSHFKETGDPTVLRANALRHGDRSLFTMLSAFIPSPQVQQCHYMIMPSKQLDKLPIRTLLDRLLIAREMGAKVMKKTEMPTSLSTFYRERVTISGHRNPVYSVVFDKTNRRLFTGSDDFLVKVWCVRTGYLIHTIRGHQNAIADIAINQENTLIATASTDGCVRVWTMDEYKPIFCLRPNSNTIKPFTTVKFSPSPRSDTRYLMATNEDGFVRLWRWDRDTLQFFDLDTPVTFSCRFRARDRLRCSSFNYTGTKFAVAGDDGFVYVFSTLPVQTKLEGTQTEDANRSNNSGRGRRRFANALFPDKNSPLNDQPVVTIGTLEGHRGSVTDLAYSHDGQRILSGSQDGTARIWTLDTQTKEWSSIVLDLKLPLPDTPIVRPSKPHSTAMSRSASYQHLPEPSQELGQLMPPLGTPTEEEPMQVDFMSHEETEEQSPKVSMIAWSADDRWCIVASNQGEIRVYYAYNGQPACILKGHEGEIYALDNHPLDSSTLLSAGYDGNVILWDIQKQKVMTCTHHRGRTFTDCKFSKDATKYAITDEEGHCTLYSLGGLDRDYEQVRSWERGQYFMTDYQALRHFVDGTFVDEPTQQLPYAMAPSPIIDLQGVAYPNQKKLGYGRTIPTQSETFELEDQRRSACYDQEEEEMRRIKLIVLPHLDRATVARNRRDFVKMDDEEEDNSTHATQLFPPPLPPPTLLPDDSEDEDYHDDEQQAAYATSGNSSSDDEDEPGSDDFVSRSSSVRIQEEDEEDGEEGGPVTRSRAGQVPLRTLDPTRHRGRGRGRGRGSQLSRVPTTRGRPSRKRTRGRLESDDDLDEEQPVRARARRRRVAERPSYVESDLEEEEEEDEFVDVDTPQEEIFEAGPSTQPPSSTEDRKGKRRLRSNAAIIQDDDEDDDEEEEQQKKEKEPERRSVYVPSHFRIPSTSTTTEPTPTRRGRLTRSRTANEPTKPIQQRRTGRQRDVPRELSEEEIKEYEPIPWITTTERSLVKYLPQLGDRVAILTEGYKEYLKVSELKSLFDHHRIDRHEPVLFAKVSQIQWQVGPPAYCKLKLSMFELANPQQVVHQQADPVWTTLNRDETIEYTDEDGSPEFIVLWERFRASMTIFKTLKQGQRVDALYDEGQYTGTIAYCNANSMNWKRAGMPSPWAYYHVIWDDPGSNAEDLCPWELVPSGEDFRSHYDVQPSLTVAQIQRARDVIEWLSNTDDFFLYVQQVNYHDYPAYLSVIAYPICLDMVRERLENNFYRSIEGLMDDVELIKKNAQKYNADSSPAHKNAARLANFFKTRIQKPSMPLSLSRGPRKRIIKDDSDDEYDVEAAVSEEEEEEVRRPYDSDDFVRDDSDEDYSDAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N4S1</accession>
    <name>A0A1C7N4S1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_07919</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000567">
        <property type="protein sequence ID" value="OBZ84027.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N4S1"/>
    <dbReference type="InParanoid" id="A0A1C7N4S1"/>
    <dbReference type="OrthoDB" id="2330750at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="158"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="215"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="337"/>
            <end position="508"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="158"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="215"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="337"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="368"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="398"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="462"/>
            <end position="482"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ84027.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="552" mass="61512" checksum="0C7ED950E5CDDD21" modified="2016-11-30" version="1">MLENRQSAHYWSNSHTQIGVAHDRSVSAQQNMLEMVPFSELQQGELYIIKIKLVVIALFQGWDDDMCCFSVLRSDLVTDLPIRWSEARYLPNDFDAYPAFDRLGNPPIHLWSKNISSSMPYNWFSMFEEARQWQRQWHASFEEPPIPLENEHHYDENVTTCGSENLPQHHQKPHQETIADETTAEENKETEDSATCGSYASQDAAFLPRHRLSSAGTQEIQSRPQQQLNRSNSSFSSSVSASESLLINRAHVRDYILRPQVEEPTHSRPTPAVQLRKQYGELAEVTQQQLPAFIPSSSQQIVSSSLTLAQAPSTISAQAQAQTVLAQAQAVLSSQSCASSLPPSCPTSPSSAPRSTLLPSVTPLPPLHTEKHPSQIKESRSSSAEKTKNASFISSKPETQHIEPKQPENKQPETNLKQRRSLSSFFTRKKKNKKPTEEAKKDSKHRKSAPPTPLITPKQTASLSEVVPLPSLSTSTTMPTLTNVSSVTAPEEKTKKRVSSIKPSKSMASMNSKMELYDMDSLLDMQATFAFLNGDNEHPSLASSSTHLTKAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N4V4</accession>
    <name>A0A1C7N4V4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_09595</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000887">
        <property type="protein sequence ID" value="OBZ82354.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N4V4"/>
    <dbReference type="STRING" id="101091.A0A1C7N4V4"/>
    <dbReference type="InParanoid" id="A0A1C7N4V4"/>
    <dbReference type="OrthoDB" id="2285161at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="77"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="92"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="135"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ82354.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="135" mass="15153" checksum="5F9F84FCC78AA31F" modified="2016-11-30" version="1" fragment="single">MPPSRGRRSTLSHLTPEEILRLSQLFETHRSNFSCMQCHATGTLHRNGHSTGNPPQPSFICKQCSKTHNARTVFETLTKPSQPTDTNDSHSMEISSSFPLTQQSHGDSVETLRALVLQLQEELNRTKAELQQARS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N529</accession>
    <name>A0A1C7N529_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">60S ribosomal protein L3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">RPL3_0</name>
        <name evidence="4" type="ORF">A0J61_07707</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uL3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000537">
        <property type="protein sequence ID" value="OBZ84233.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N529"/>
    <dbReference type="STRING" id="101091.A0A1C7N529"/>
    <dbReference type="InParanoid" id="A0A1C7N529"/>
    <dbReference type="OrthoDB" id="1611972at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022625">
        <property type="term" value="C:cytosolic large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="4.10.960.10:FF:000002">
        <property type="entry name" value="60S ribosomal protein L3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.30.10:FF:000351">
        <property type="entry name" value="Ribosomal protein L3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.10">
        <property type="entry name" value="Translation factors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045077">
        <property type="entry name" value="L3_arc_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000597">
        <property type="entry name" value="Ribosomal_uL3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11363">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11363:SF5">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN UL3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00297">
        <property type="entry name" value="Ribosomal_L3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="Translation proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OBZ84233.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="174" mass="19576" checksum="EE67F78085AEDC5B" modified="2016-11-30" version="1">MIDIIATTKGHGFEGVTHRWGTKKLPRKTHRGLRKVACIGAWHPSRVMYSVARAGQRGYHRRTEINKKIYRIAKGSDAKSGTTEYDLTEKNITPMGGFPHYGVVNDDFVMIKGCCAGSKKRVITLRKSLTVHTKRSALEKVTLKFIDTSSKFGHGRFQTAAEKHQFMGTLKKDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N599</accession>
    <name>A0A1C7N599_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Glutamyl aminopeptidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">ENPEP</name>
        <name evidence="11" type="ORF">A0J61_07651</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peptidase M1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000529">
        <property type="protein sequence ID" value="OBZ84302.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N599"/>
    <dbReference type="STRING" id="101091.A0A1C7N599"/>
    <dbReference type="InParanoid" id="A0A1C7N599"/>
    <dbReference type="OrthoDB" id="79562at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070006">
        <property type="term" value="F:metalloaminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042277">
        <property type="term" value="F:peptide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043171">
        <property type="term" value="P:peptide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd09603">
        <property type="entry name" value="M1_APN_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.390.10">
        <property type="entry name" value="Neutral Protease Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1730">
        <property type="entry name" value="tricorn interacting facor f3 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045357">
        <property type="entry name" value="Aminopeptidase_N-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042097">
        <property type="entry name" value="Aminopeptidase_N-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001930">
        <property type="entry name" value="Peptidase_M1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050344">
        <property type="entry name" value="Peptidase_M1_aminopeptidases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014782">
        <property type="entry name" value="Peptidase_M1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027268">
        <property type="entry name" value="Peptidase_M4/M1_CTD_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11533:SF299">
        <property type="entry name" value="AMINOPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11533">
        <property type="entry name" value="PROTEASE M1 ZINC METALLOPROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01433">
        <property type="entry name" value="Peptidase_M1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17900">
        <property type="entry name" value="Peptidase_M1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00756">
        <property type="entry name" value="ALADIPTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63737">
        <property type="entry name" value="Leukotriene A4 hydrolase N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55486">
        <property type="entry name" value="Metalloproteases ('zincins'), catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0031">Aminopeptidase</keyword>
    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Aminopeptidase N-like N-terminal" evidence="10">
        <location>
            <begin position="34"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M1 membrane alanine aminopeptidase" evidence="9">
        <location>
            <begin position="250"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="826"/>
            <end position="860"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF17900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="OBZ84302.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="865" mass="98865" checksum="8701F0301C8AE714" modified="2016-11-30" version="1">MPHNLCCSSKGGDSFFSASAVNQYAPNKVIEPIHLDINVHFEDLTKKSFTGKVTVTFKHTGKALVSSPKDLSKILLNAEDFENVNVTGDGLKDFHYDGHHIHLFWQQAFAKQEERKVTIEYTIESPTAGLYFNKDDENLNATPVWAITDHETEKARYWLPTVDFPTVRTKLSWTITAPKQYTSLANGTLTSTETSDNFTTTKWELDHPCPSYLICFAVGEFIEVDDGEVDGKPIKYYTAKGYAKEDLKRSFDQTPKMIRWLQNKLGVPFPWTKYYQIALPAIRGAMENISLVTWVEVLLLDETLALERKLIVDTVNIHEMGHTYFGDLLVIRHFEHAWLKESWATYIESCWLQDNASEDEFRYEMLQNSTSYINECGSYMRPIVTRKYDASWDMFDMHTYPGGAWRIHMLRKRLGEEVFWHAIQIYIERFYNKTVQTSDFQNVLEEVSGLNLTRFFDEWLYSKGYPKLSGKYEYEADKNRVKISIAQTQVNAAEQIPLFAFDLDVVITTDKEEKASTTLTFDRDDSATGFIHLPEGQKPSQISIDPEGKVLFAIEMPSIDRDVLIGTAKHSKNLIDRIMAYSELISSGSRPALKAVHEAILKEPFYGVRVKCANQLAKQNSAYSLQILTELLDNEKDPMALEHIAASAKAVDDRIRASLLRLLKRENLPYRAHCNALISLGSQRNPEDLEYLLQVAKDDSKLGQHGIIRSGALKALGQHRSEEAFRYLLGRVHYKQEHFRARPFALQGLIYSAEWQTKRLKNEAVEALETLIRDPNSSVRRVAVAGLVKMNVTSKYGQIATTKSMYSTDEQAWIDRKLVELRSSGSNGSQKEINAQKETIDKLETRVKKLEEKLALQELEENASK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N5M3</accession>
    <name>A0A1C7N5M3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Cell division control protein 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">CRK2</name>
        <name evidence="4" type="ORF">A0J61_07637</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000526">
        <property type="protein sequence ID" value="OBZ84317.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N5M3"/>
    <dbReference type="STRING" id="101091.A0A1C7N5M3"/>
    <dbReference type="InParanoid" id="A0A1C7N5M3"/>
    <dbReference type="OrthoDB" id="413582at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050108">
        <property type="entry name" value="CDK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008266">
        <property type="entry name" value="Tyr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24056">
        <property type="entry name" value="CELL DIVISION PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00109">
        <property type="entry name" value="PROTEIN_KINASE_TYR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="4" id="KW-0132">Cell division</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Protein kinase" evidence="3">
        <location>
            <begin position="1"/>
            <end position="305"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OBZ84317.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="307" mass="35450" checksum="89BE4379ED72A84D" modified="2016-11-30" version="1">MMGCMSGTFACIEKKVLKDGRHVAYKTYSKSHGKLVYKHFKRELNICKQLQTKHPYHPNILYLMDYQETSTNCILVFDCFEQSLQSLLDKKDPFLAHQCLNQIAKGLAYLHQYAIIHCDLSPSNILINLNSWHMVICDFGCAHTMDELIDSSQEEIGTRLYKAPEHLFGNKQCSPSTDIWSLGAIFTQLLIGYPIFEGHSDIEQIARIVFRLGKPSEEIQETELSNCPDIHKLDFFTESEDEDEIEFDSEEEYVEFTSIRRPLSIVLEQEKLSSKDCTLILGLLTWSMQERQDNFLSIINHHQTNSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N5R5</accession>
    <name>A0A1C7N5R5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Solute carrier family 2, facilitated glucose transporter member 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">Slc2a1_1</name>
        <name evidence="11" type="ORF">A0J61_07974</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000575">
        <property type="protein sequence ID" value="OBZ83976.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N5R5"/>
    <dbReference type="STRING" id="101091.A0A1C7N5R5"/>
    <dbReference type="InParanoid" id="A0A1C7N5R5"/>
    <dbReference type="OrthoDB" id="4540492at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015149">
        <property type="term" value="F:hexose transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045263">
        <property type="entry name" value="GLUT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00879">
        <property type="entry name" value="SP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23503:SF8">
        <property type="entry name" value="FACILITATED GLUCOSE TRANSPORTER PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23503">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00171">
        <property type="entry name" value="SUGRTRNSPORT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00216">
        <property type="entry name" value="SUGAR_TRANSPORT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00217">
        <property type="entry name" value="SUGAR_TRANSPORT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0762">Sugar transport</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="25"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="99"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="130"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="153"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="186"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="214"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="320"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="358"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="388"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="414"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="450"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="479"/>
            <end position="500"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="10">
        <location>
            <begin position="33"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="275"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="11">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="OBZ83976.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="530" mass="57360" checksum="A38A0227096E2218" modified="2016-11-30" version="1" fragment="single">FPAIKFCNKQINVTSNRIMDSRTSGLHPFVIFCALIAALGAFNNGVNTSALNIPSGALTQCPGVPYGTVTYYPNSPLPQCIPMSDCKFFLKKKEKLTEGAATGMFAVGGLLGAMMASYMATKFGRRDSMIILNISFFIGAILLSLATEPGQFAVGRIFVGIGSGFMTVVVSMYIAEISPPKYRGALGCCLQLLMTVGILIIECIGLGLSSAIGWRIVVVITVVPALIQMLVLPFCARSPRWLISQNRIDEARVQLMRLRHGDVQEEFTDMILSLTKGGNSNEPKKAPANDDGFDNEEGSAEKPFEGEENISIVQIFKIPVLAVLTLKMMVVHASSQLTGINAVMYYSTSIFENSFGDTAKYVTIGVSGLNVVVTMVGLVLADRLGRKMLMYISAFGMCVWAVLMTIGLHFDVSALQVVSIYVFVGFYAIGLGVIPFVINSEVFPTYAVSASSSIALVINWLCNFIVGLIFPALKTACGPYVFLIFAGLSLVFGLFILFLVPETKQKSIDQLGRELGWYGINPADINGQKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N5S6</accession>
    <name>A0A1C7N5S6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Protein rolling stone</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_07967</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000573">
        <property type="protein sequence ID" value="OBZ83986.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N5S6"/>
    <dbReference type="STRING" id="101091.A0A1C7N5S6"/>
    <dbReference type="InParanoid" id="A0A1C7N5S6"/>
    <dbReference type="OrthoDB" id="419711at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12242:SF1">
        <property type="entry name" value="MYND-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12242">
        <property type="entry name" value="OS02G0130600 PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="41"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="67"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="112"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="147"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="178"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="215"/>
            <end position="235"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ83986.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="270" mass="31714" checksum="72EECB3DF3B50DEF" modified="2016-11-30" version="1">MMYKDQRIEPSKYAIVNWLGLSELVPERAVTSYWFSSKIFFVIRLILTLYSTIVLWTDIGITHSGHFFMFFTSFTFIGLHAYLVTSCVHHARYLMNKNMDFMLNQYAILNYLYMYLYSTVITFNIVTPVVYWSLLNSTSTAKTPVEVWLNVSVHGVSFFLMIFDVIMNRMKIPIRMVFFPFATIVGFMLFSFVVYACNGIWIYPFLDWKQGGMAAVWYIMVGVICVIGFFVQYLIHWLRDFIARKLGKTTTQELDEKAETPYKMEEAQMV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N615</accession>
    <name>A0A1C7N615_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">LIN1-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">SPBC83.09c</name>
        <name evidence="2" type="ORF">A0J61_07379</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000495">
        <property type="protein sequence ID" value="OBZ84562.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N615"/>
    <dbReference type="FunCoup" id="A0A1C7N615">
        <property type="interactions" value="691"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N615"/>
    <dbReference type="InParanoid" id="A0A1C7N615"/>
    <dbReference type="OrthoDB" id="331341at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005682">
        <property type="term" value="C:U5 snRNP"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039905">
        <property type="entry name" value="CD2BP2/Lin1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13138:SF3">
        <property type="entry name" value="CD2 ANTIGEN CYTOPLASMIC TAIL-BINDING PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13138">
        <property type="entry name" value="PROTEIN LIN1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="201"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="268"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="35"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="75"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="134"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="148"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="201"/>
            <end position="220"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ84562.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="338" mass="39096" checksum="17839B9874CB77CD" modified="2016-11-30" version="1">MSYAQKRSFDFAGSSSKRVRFDEKSKSRKKATGDTDFEFDHEDQLEERKTRRGAVNFDVYGSDDEEVGGGMYSDSDQEEKEEEEPAPKQDEEFDMFGGDGDDKMEVDKKGKKKATTDELLEGQELNSHSRDRLEADDDEDDDEDDVEDGQKKQSRIEAFNMKEELEEGSVDSNGNYIRNKVDPQAFHDNWMKGITRKDINKAKEAQQKRDREEALKEAERQSNLPQSETDIYLALVHHLRPGQSVQEALTSLANSLPKKLPAWKQKMLDKKNKNKPVQQSQLTEQEETERREKVEKITGLADQMMALGHFNIYQDTYEMMIRHLRKEGAVDQDWLPPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N6F7</accession>
    <name>A0A1C7N6F7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Eukaryotic translation initiation factor 5A</fullName>
            <shortName evidence="8">eIF-5A</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">ANB1</name>
        <name evidence="11" type="ORF">A0J61_07771</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Translation factor that promotes translation elongation and termination, particularly upon ribosome stalling at specific amino acid sequence contexts. Binds between the exit (E) and peptidyl (P) site of the ribosome and promotes rescue of stalled ribosome: specifically required for efficient translation of polyproline-containing peptides as well as other motifs that stall the ribosome. Acts as ribosome quality control (RQC) cofactor by joining the RQC complex to facilitate peptidyl transfer during CAT tailing step.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="PTM">
        <text evidence="8">eIF-5A seems to be the only eukaryotic protein to have a hypusine residue which is a post-translational modification of a lysine by the addition of a butylamino group.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the eIF-5A family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000545">
        <property type="protein sequence ID" value="OBZ84179.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N6F7"/>
    <dbReference type="FunCoup" id="A0A1C7N6F7">
        <property type="interactions" value="453"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N6F7"/>
    <dbReference type="InParanoid" id="A0A1C7N6F7"/>
    <dbReference type="OrthoDB" id="9975114at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043022">
        <property type="term" value="F:ribosome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045901">
        <property type="term" value="P:positive regulation of translational elongation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045905">
        <property type="term" value="P:positive regulation of translational termination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006452">
        <property type="term" value="P:translational frameshifting"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd04468">
        <property type="entry name" value="S1_eIF5A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.30.30:FF:000007">
        <property type="entry name" value="Eukaryotic translation initiation factor 5A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.140:FF:000034">
        <property type="entry name" value="Eukaryotic translation initiation factor 5A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001884">
        <property type="entry name" value="IF5A-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048670">
        <property type="entry name" value="IF5A-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020189">
        <property type="entry name" value="IF5A_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014722">
        <property type="entry name" value="Rib_uL2_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019769">
        <property type="entry name" value="Trans_elong_IF5A_hypusine_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008991">
        <property type="entry name" value="Translation_prot_SH3-like_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00037">
        <property type="entry name" value="eIF_5A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11673">
        <property type="entry name" value="TRANSLATION INITIATION FACTOR 5A FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01287">
        <property type="entry name" value="eIF-5a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21485">
        <property type="entry name" value="IF5A-like_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF003025">
        <property type="entry name" value="eIF5A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01376">
        <property type="entry name" value="eIF-5a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50104">
        <property type="entry name" value="Translation proteins SH3-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00302">
        <property type="entry name" value="IF5A_HYPUSINE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0251">Elongation factor</keyword>
    <keyword evidence="7 8" id="KW-0385">Hypusine</keyword>
    <keyword evidence="11" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="6 8" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="Translation initiation factor 5A C-terminal" evidence="10">
        <location>
            <begin position="85"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="109"/>
            <end position="128"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022768"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU362005"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM01376"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="OBZ84179.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="157" mass="17381" checksum="43308298EB29B3CA" modified="2016-11-30" version="1">MSEEHDHTFESADAGASLTYPMQCSALRKNGHVVIKGRPCKIIEMTTSKTGKHGHAKVHLVATDIFTGRKYEDLSPSTHNMDVPNVVRNDYDLINIDDGFLSLMEKDGSTKDDVKLPEGELGEKMEQDFEEGKELIVSVVSSMGEEHALSYKEAPKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N6J7</accession>
    <name>A0A1C7N6J7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Replication factor C subunit 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">rfc1</name>
        <name evidence="10" type="ORF">A0J61_07283</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the activator 1 large subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000484">
        <property type="protein sequence ID" value="OBZ84661.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N6J7"/>
    <dbReference type="FunCoup" id="A0A1C7N6J7">
        <property type="interactions" value="902"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N6J7"/>
    <dbReference type="InParanoid" id="A0A1C7N6J7"/>
    <dbReference type="OrthoDB" id="446168at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005663">
        <property type="term" value="C:DNA replication factor C complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003682">
        <property type="term" value="F:chromatin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003689">
        <property type="term" value="F:DNA clamp loader activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902983">
        <property type="term" value="P:DNA strand elongation involved in mitotic DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006272">
        <property type="term" value="P:leading strand elongation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006298">
        <property type="term" value="P:mismatch repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070914">
        <property type="term" value="P:UV-damage excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd00009">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18140">
        <property type="entry name" value="HLD_clamp_RFC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.60:FF:000021">
        <property type="entry name" value="Replication factor C subunit 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.10190:FF:000001">
        <property type="entry name" value="Replication factor C subunit 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000395">
        <property type="entry name" value="Replication factor C subunit 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.272.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10190">
        <property type="entry name" value="BRCT domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001357">
        <property type="entry name" value="BRCT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036420">
        <property type="entry name" value="BRCT_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008921">
        <property type="entry name" value="DNA_pol3_clamp-load_cplx_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013725">
        <property type="entry name" value="DNA_replication_fac_RFC1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012178">
        <property type="entry name" value="RFC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047854">
        <property type="entry name" value="RFC_lid"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23389">
        <property type="entry name" value="CHROMOSOME TRANSMISSION FIDELITY FACTOR 18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23389:SF6">
        <property type="entry name" value="REPLICATION FACTOR C SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25361">
        <property type="entry name" value="AAA_lid_RFC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00533">
        <property type="entry name" value="BRCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08519">
        <property type="entry name" value="RFC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036578">
        <property type="entry name" value="RFC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00364">
        <property type="entry name" value="DISEASERSIST"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00292">
        <property type="entry name" value="BRCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52113">
        <property type="entry name" value="BRCT domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48019">
        <property type="entry name" value="post-AAA+ oligomerization domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50172">
        <property type="entry name" value="BRCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0235">DNA replication</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BRCT" evidence="9">
        <location>
            <begin position="79"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="159"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="31"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="10">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006116"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00020401"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OBZ84661.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="699" mass="77849" checksum="37D8A48BF3836683" modified="2016-11-30" version="1" fragment="single">KAKKASSPPPTKKTTVKQEDTNKKRRVLPTKKAEDAPIKQEEGKQEEEKPKPAAKKNYFAMMKSVEGPKALGTRPEPVGAPNCLDGLAFVISGQYETLTKEQTKDIVMRYGGRVTGAVSGKTHYLLRGRDAGESKLAKAKSVGTKILNEDEFYELVENPAEKKPSTAPPPKAAAPKIAKGKGKAAETKTDTSNSVDTKSLLWTEKYKPTELKEIIGNKELVNTISQWLAQWQESLANGFEGSDIHSHRAVLLSGPPGIGKTTTANVVARVNGYEALEFNASDVRSKKILEESISEMMDNRTMTEFFQASKNQANRMIKGKKVVLIMDEVDGMSEGDRGGAAELARMIKESKIPVICICNDSRSQKVAPLLRVCYEAKFRRSTAAQIRSRILSIAYKENLNITPNAIDELVAATQNDIRQIINILSAYRINETSLSYDQAKTLGKSNQKNSTVGLFDIPGELLTGGSWRSKSLTEKYEIYFNDYSLSNLMIQMYTYFLKQENYLKCLPELARSETGNPKETACNEMDLFAKASEAIADGDLADAMIHGTTQHWSLMPVHSIFSCVRPASFVRGGVQSRYNFPGWLGQNSKADKYSRQLSEVQARMRLKASGDKYEIRQNYIPTLNDRIIKELQDGDYDGAMEIMDSYYLDRECLDTFNDLTFAPTGKGPLAQLPTKIKSTLTRRYNNSKHPVLFQSIKPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N6S7</accession>
    <name>A0A1C7N6S7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative PH domain-containing protein PB16A4.02c</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_07244</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000479">
        <property type="protein sequence ID" value="OBZ84708.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N6S7"/>
    <dbReference type="STRING" id="101091.A0A1C7N6S7"/>
    <dbReference type="InParanoid" id="A0A1C7N6S7"/>
    <dbReference type="OrthoDB" id="2157866at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.29.30:FF:000286">
        <property type="entry name" value="PH-protein kinase domain containing protein"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001849">
        <property type="entry name" value="PH_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051707">
        <property type="entry name" value="PI-Interact_SigTrans_Reg"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14336:SF8">
        <property type="entry name" value="PROTEIN OPY1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14336">
        <property type="entry name" value="TANDEM PH DOMAIN CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00169">
        <property type="entry name" value="PH"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00233">
        <property type="entry name" value="PH"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50003">
        <property type="entry name" value="PH_DOMAIN"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PH" evidence="2">
        <location>
            <begin position="62"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="domain" description="PH" evidence="2">
        <location>
            <begin position="292"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ84708.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="482" mass="54693" checksum="8991D6F20D68ACEC" modified="2016-11-30" version="1">MQPKINSVASTKPNRLVLSEDEDEENIISNNQKYVSDGDNDDDEPVIEPVSAEALELLKAEKVLKAGYLLKKGEKRRTWKKRWFVLRSTKLAMYKDKKEYKLLRLIDLHEIHKVVQVTTKHKYKFVFAFVTAKRMYYVQANDQQEMDDWFNSVNKAKEEQRLYDADDDTSSVDRDQEFAKDVIASYRQNHVVSVMQNQRRRSSGLIETSKSAIDTTSKLKPVDIPKKTNNFPVVSSYSTSQSSEYVLGQSYPLSPTSDFQQQNGLEGVASSEDDEEYSVDRANIESEENRNRVLVEGYLLKLGRNKGWRKRWFVLRTDTLAYYEDDKEYSPHRIIPLHHIIDSLEIEPVSKSKQNCFKIIIPKRSYVLCASTEADMDAWLNALVVAIKRAKKDADDTSPLTPHPQSYQSRLLSLIPENQTPQLQKVNSTPSSIDSFENISHISGVSGACGCGGAGGALGAAPTPNSLLQLHSRASERFGRAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-06-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N7K4</accession>
    <name>A0A1C7N7K4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_06822</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000430">
        <property type="protein sequence ID" value="OBZ85125.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N7K4"/>
    <dbReference type="InParanoid" id="A0A1C7N7K4"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ85125.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="66" mass="7702" checksum="D65B53A205AF8714" modified="2016-11-30" version="1">MLLLHNIISQVLVLTDFVRPYQILISNRSNPVKWSLILTKQSLVEIQQKTEIELLQAIRKFRGQEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N8E0</accession>
    <name>A0A1C7N8E0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Cytokinesis protein sepA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">sepA_1</name>
        <name evidence="5" type="ORF">A0J61_06560</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the formin homology family. BNI1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000401">
        <property type="protein sequence ID" value="OBZ85395.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N8E0"/>
    <dbReference type="STRING" id="101091.A0A1C7N8E0"/>
    <dbReference type="InParanoid" id="A0A1C7N8E0"/>
    <dbReference type="OrthoDB" id="1104827at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015629">
        <property type="term" value="C:actin cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005938">
        <property type="term" value="C:cell cortex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032153">
        <property type="term" value="C:cell division site"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043332">
        <property type="term" value="C:mating projection tip"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003779">
        <property type="term" value="F:actin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031267">
        <property type="term" value="F:small GTPase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051017">
        <property type="term" value="P:actin filament bundle assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051016">
        <property type="term" value="P:barbed-end actin filament capping"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1903475">
        <property type="term" value="P:mitotic actomyosin contractile ring assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.150">
        <property type="entry name" value="Formin, FH3 diaphanous domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051661">
        <property type="entry name" value="Actin_filament_regulator"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010472">
        <property type="entry name" value="FH3_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014768">
        <property type="entry name" value="GBD/FH3_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010473">
        <property type="entry name" value="GTPase-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47102">
        <property type="entry name" value="PROTEIN BNI1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47102:SF2">
        <property type="entry name" value="PROTEIN BNI1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06367">
        <property type="entry name" value="Drf_FH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06371">
        <property type="entry name" value="Drf_GBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01139">
        <property type="entry name" value="Drf_FH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01140">
        <property type="entry name" value="Drf_GBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51232">
        <property type="entry name" value="GBD_FH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GBD/FH3" evidence="4">
        <location>
            <begin position="78"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="125"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="511"/>
            <end position="545"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="125"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="140"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="579"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00037935"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51232"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OBZ85395.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="579" mass="66057" checksum="E53EF54D29740C26" modified="2016-11-30" version="1" fragment="single">MDLFGRNKAKVKKRPVIDPPMIETATTTNTTQMLQHSPISPHSITDDYMTGVGRLLDTTSIRSSQSSTPSVDIESTNAEHMSEAEIEEFFERMLTRRGIHDATARAKMSSFPMEKKRLMVAQDIQSESNTSATQTNRRGGGMDKKSEHQTESKGPEYYVQKLSDMSRGVNTKIVSHLAVGLRTMPLSWVRQFIDMQGLLVITDLLEAFNKAKNKQELSLSVEADLLKCFKALLNNRVGAREALKHPRCIQEVVHCIISPSVTSRRLVCEVLVFMCYYEVPVGQDLVLKALDQLRDKNGGLGRFDAWLRELEITLGGRGRMGSMVGASEDFKQMAAYGSPDNQLTEYALYNMILVNAIINVVDDPEIRIHLRNQMTASGLERIMDKMLELSDEHVDRQIREFKNLAENDQDELMDLYNDYVISDQNDPRDVFECILTNLEGTRAYDFFLSCLQHLLLVNNEENGMKSRYFQVIDNLVSQVVLDHKGLAEDFSTDYSTTVQHLMHKLDNQDQLKTSLDELKDLQHNYDELEKERDMLRHELSQQADALDLVQLKEKTASLEDLLRISRHTISTLQEKLRDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N8E8</accession>
    <name>A0A1C7N8E8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">NADP-dependent alcohol dehydrogenase C 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">adhC2_2</name>
        <name evidence="7" type="ORF">A0J61_08326</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 5">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the zinc-containing alcohol dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000630">
        <property type="protein sequence ID" value="OBZ83624.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N8E8"/>
    <dbReference type="FunCoup" id="A0A1C7N8E8">
        <property type="interactions" value="328"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N8E8"/>
    <dbReference type="InParanoid" id="A0A1C7N8E8"/>
    <dbReference type="OrthoDB" id="1879366at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016616">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05283">
        <property type="entry name" value="CAD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000022">
        <property type="entry name" value="Cinnamyl alcohol dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002328">
        <property type="entry name" value="ADH_Zn_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047109">
        <property type="entry name" value="CAD-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="ER"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42683">
        <property type="entry name" value="ALDEHYDE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00059">
        <property type="entry name" value="ADH_ZINC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Enoyl reductase (ER)" evidence="6">
        <location>
            <begin position="19"/>
            <end position="349"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU361277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OBZ83624.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="351" mass="39295" checksum="5F7446FE9D296A3F" modified="2016-11-30" version="1">MSSTESDIFNGWAGTGKGKPLERMQLSLRRWDEDCVDINITHCGVCASDLHCLDQDDQWGPTDYPCVVGHEIVGVVARVGKNVSRFKVGDRVGVGAQCTSCHECDECNNHRENLCPNFGMTYNARWPNGDKTYGGYADKWRGDHRFVFKIPDHLSSEVAATFFCAGITSYSPLKRTGVNEDSVVGIMGIGGLGHYGILWAKAMGAKVVAISTGDRKRNVSYELGCDDFIDSTNPDDMARYEKKFTHILCTGCSPDFQWSTYLNLIRGNGYFLNVNAPAWELPPMPPFMMLMAQVFIQGSCLGSPVEIEEMLKFAEQKNVRPWITMFSMKDVNKVLEDFRAGKPRFRFVLEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N8N1</accession>
    <name>A0A1C7N8N1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Presequence protease, mitochondrial</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">Pitrilysin metalloproteinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">A0J61_06451</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Degrades mitochondrial transit peptides after their cleavage in the intermembrane space or in the matrix, and presequence peptides; clearance of these peptides is required to keep the presequence processing machinery running. Preferentially cleaves the N-terminal side of paired basic amino acid residues. Also degrades other unstructured peptides. May function as an ATP-dependent peptidase as opposed to a metalloendopeptidase.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Monomer and homodimer; homodimerization is induced by binding of the substrate.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase M16 family. PreP subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000390">
        <property type="protein sequence ID" value="OBZ85495.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="FunCoup" id="A0A1C7N8N1">
        <property type="interactions" value="7"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N8N1"/>
    <dbReference type="InParanoid" id="A0A1C7N8N1"/>
    <dbReference type="OrthoDB" id="4953at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.830.10:FF:000015">
        <property type="entry name" value="Putative zinc metalloprotease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.830.10:FF:000031">
        <property type="entry name" value="Putative zinc metalloprotease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.830.10">
        <property type="entry name" value="Metalloenzyme, LuxS/M16 peptidase-like"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011249">
        <property type="entry name" value="Metalloenz_LuxS/M16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007863">
        <property type="entry name" value="Peptidase_M16_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013578">
        <property type="entry name" value="Peptidase_M16C_assoc"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43016:SF16">
        <property type="entry name" value="METALLOPROTEASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_4G07610)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43016">
        <property type="entry name" value="PRESEQUENCE PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05193">
        <property type="entry name" value="Peptidase_M16_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01264">
        <property type="entry name" value="M16C_associated"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63411">
        <property type="entry name" value="LuxS/MPP-like metallohydrolase"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase M16C associated" evidence="6">
        <location>
            <begin position="468"/>
            <end position="730"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007575"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00020167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00034552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00045897"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM01264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OBZ85495.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="1023" mass="115146" checksum="52545CE47ED07EEC" modified="2016-11-30" version="1">MSNFKEVCVISTDFGVNFTKLKSERTGLTVMLADIEGPLVNGYFALATESFDDFGCPHTLEQCSHANKQSSLVFLGSEQYPYKGVLDLLANRAIAQGTNAWTDVDHTCYTITTAGSEGFLKLLPIYVDHILYXTLTETGYHTEVHHINGKGEDAGVVYSEMQGCQNLGDDRLHLRMKRMLHPESCGYRYETGGLMERLRELSVEKIRNYHQSYYRPDNLCLIVTGQVNKESLLKALEPVEESILKKGELPAMQRPWVETGNFPNLKENLTETVLFADEDESMGSVLIAWNGPMCNEKPTDDYLQQKELEVLNEYLTDSPVSVLQKEFVETEDALCTDVDFHISDHIKSTLMFTASSVAIEEIENFPKEFFGLLKRLVDTNDIDMTRMATVIEKEVLKLLDSAETDAHGTAAAAVAISDFLYGSPDGKDLKNAVKDQEYLKRLATYSAEDWLRILKKWYLDAPHIILFGKPSAEFAEQQTEEETNRVEKQRAELGPDKLAELQKKLDDAMAKNDLPVPKEILENFEIPSVSTIKFIDVITAKNNDRTLSNPVQDHINQDNSANVPICIQYDHVKSHFTKISVHINTSAVPSHLLLYTRLFLKAIFSLPIEKDGQLISYEDVVKGLGEDTVEYEASLGTSFGFKEFAVFTLKAKASKFEKSIQWLRDILWNTVFTAERLKIVAFQIINDIPQYKRDGHDMGNATLRALQIDPKKSAYGARNILFQNIFLKEVLKRLENDAEGVLEDINQFLCSPKNMRVHVTGDILHLDRPRTAFRDFRPQTPCEYEPLTPITLSQQVLLPAGNQPGKHSFVVTLPSIENSFSYHSVKGPHQFDDPDIAPLLVMIELLDTMEGIFWKLIRGQGLAYSCFLDANIESGLINFTVFRSPDAFKAFEQAKLVIEQLVDQKMKIDAAAVHGAKSAVIYSLVAKENTMDRAALQSFVNQALKKMPATYNRDLLVAIQAVDMADLQRVLNKYFVNMFKPDTSNVVVVSTPAKVADIQHGFNNLGFNMKSITLNDITIDGLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N8R5</accession>
    <name>A0A1C7N8R5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">A0J61_06611</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000407">
        <property type="protein sequence ID" value="OBZ85338.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N8R5"/>
    <dbReference type="STRING" id="101091.A0A1C7N8R5"/>
    <dbReference type="InParanoid" id="A0A1C7N8R5"/>
    <dbReference type="OrthoDB" id="2152896at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="3">
        <location>
            <begin position="172"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="122"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="229"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="122"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="233"/>
            <end position="261"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OBZ85338.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="279" mass="31413" checksum="53254646FCAF49E6" modified="2016-11-30" version="1">MSSLLTFQLIQQQQEQEKKENSCLPSPPSSFCGEENVSVVISEQKLPPQLQCRRDSLQTVFNDMTLKDCSTSLPENYTIDHSTQKHLTASKPANRKIFSSSFNPSFLHPPGATATAAATGGLTVRNNNTNSNNNSTASISIHSNHNRSRQQDISNSVRKKSRGLSESFSGQYRCNDCGKSYKHPNCLQKHRWEHSEEWEITRKLPLTKHQQVQMLEAAAILAGINKNYRPKDEEEDVQIDDDDDNKEDSEDEESIVIDDEEEKGHTSSIDSLGIFMDDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N8X7</accession>
    <name>A0A1C7N8X7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">N-acetyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_06874</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000436">
        <property type="protein sequence ID" value="OBZ85079.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N8X7"/>
    <dbReference type="STRING" id="101091.A0A1C7N8X7"/>
    <dbReference type="InParanoid" id="A0A1C7N8X7"/>
    <dbReference type="OrthoDB" id="416222at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016747">
        <property type="term" value="F:acyltransferase activity, transferring groups other than amino-acyl groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04301">
        <property type="entry name" value="NAT_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43072">
        <property type="entry name" value="N-ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13508">
        <property type="entry name" value="Acetyltransf_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="27"/>
            <end position="185"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ85079.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="341" mass="38772" checksum="DB42AF6A3811AAFB" modified="2016-11-30" version="1">MSSKLPVTIPVPSAPVCSLPKDPLETITAFDCTDKNLQSAYALWDTVFRACWPLSFESFKKVLTHLEQPYHIAVYDDQGKLVGFAATQTVVSENAGQLALLMVHPEYRNKGVGTRLNDCCLNMFRSNGSSVMLGSTYPRFFCGVPNDDLGEQAQAFFEHRGYSFNNTVWDMMGDVSQYEIPKQIQERMIKENIWFGRITKDQTQELFDFQSKYFDFWLSTYKHHIELGDYQDILIAREHDENGRLIGSLILFCPGQSSPHRTDLIWTHESLFGSKSGGMACVGVASEDRGRGIGLGLVSYANSALRKRGVYKSYVDWVELTDFYGRTNYCKWRSYRLGAIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N965</accession>
    <name>A0A1C7N965_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Homoserine kinase</fullName>
            <ecNumber evidence="3">2.7.1.39</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="primary">THR1</name>
        <name evidence="15" type="ORF">A0J61_06319</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Commits homoserine to the threonine biosynthesis pathway by catalyzing its O-phosphorylation.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>L-homoserine + ATP = O-phospho-L-homoserine + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13985"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57476"/>
            <dbReference type="ChEBI" id="CHEBI:57590"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.39"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="11">
            <dbReference type="Rhea" id="RHEA:13986"/>
        </physiologicalReaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Amino-acid biosynthesis; L-threonine biosynthesis; L-threonine from L-aspartate: step 4/5.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the GHMP kinase family. Homoserine kinase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.39" evidence="3"/>
    <dbReference type="EMBL" id="LUGH01000376">
        <property type="protein sequence ID" value="OBZ85630.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N965"/>
    <dbReference type="FunCoup" id="A0A1C7N965">
        <property type="interactions" value="142"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N965"/>
    <dbReference type="InParanoid" id="A0A1C7N965"/>
    <dbReference type="OrthoDB" id="195231at2759"/>
    <dbReference type="UniPathway" id="UPA00050">
        <property type="reaction ID" value="UER00064"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004413">
        <property type="term" value="F:homoserine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009092">
        <property type="term" value="P:homoserine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009088">
        <property type="term" value="P:threonine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.230.10:FF:000068">
        <property type="entry name" value="Homoserine kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.890">
        <property type="entry name" value="GHMP kinase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00384">
        <property type="entry name" value="Homoser_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013750">
        <property type="entry name" value="GHMP_kinase_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036554">
        <property type="entry name" value="GHMP_kinase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006204">
        <property type="entry name" value="GHMP_kinase_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006203">
        <property type="entry name" value="GHMP_knse_ATP-bd_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000870">
        <property type="entry name" value="Homoserine_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_Su5_D2-typ_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribsml_uS5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00191">
        <property type="entry name" value="thrB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20861:SF1">
        <property type="entry name" value="HOMOSERINE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20861">
        <property type="entry name" value="HOMOSERINE/4-DIPHOSPHOCYTIDYL-2-C-METHYL-D-ERYTHRITOL KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08544">
        <property type="entry name" value="GHMP_kinases_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00288">
        <property type="entry name" value="GHMP_kinases_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000676">
        <property type="entry name" value="Homoser_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00958">
        <property type="entry name" value="HOMSERKINASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55060">
        <property type="entry name" value="GHMP Kinase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="Ribosomal protein S5 domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00627">
        <property type="entry name" value="GHMP_KINASES_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9 15" id="KW-0418">Kinase</keyword>
    <keyword evidence="8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0791">Threonine biosynthesis</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="GHMP kinase N-terminal" evidence="13">
        <location>
            <begin position="65"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="domain" description="GHMP kinase C-terminal" evidence="14">
        <location>
            <begin position="255"/>
            <end position="315"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00017858"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00049913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00054121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF00288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF08544"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="OBZ85630.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="347" mass="37467" checksum="68D23BA0ED016B18" modified="2016-11-30" version="1">MNTPRKFRIESPCSTANIGPGFDVLGISLSLYLTMDVEILEKGSDFEMTYSGEGAEDVPLTPEHNLITKTALYVLSANGISALPKPLKIHVDNPIPLGRGLGSSGAAVVGGVLLGNALGQLNLSRDRLLDYCLMIERHPDNVAAALMGGFVASYLRELDPKDMEGVPASESLLDIALSQQVPQPPLGIGHYVNLGWAKEIKCIAIVPQFQVATAKARAVLPTQYERQDMVFNFQRLAVLTTALGQSPPNPELIYNAMQDKVHQPYRKTLIPGLPEILSTITYQKYDGLLGICLSGAGPTILALATKNFDEIAEAAIALFKKHGDFECFYKVLDVVTDGSTCIDLLKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N970</accession>
    <name>A0A1C7N970_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Conserved oligomeric Golgi complex subunit 8</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Component of oligomeric Golgi complex 8</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="primary">Cog8</name>
        <name evidence="11" type="ORF">A0J61_06311</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Golgi apparatus membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the COG8 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000375">
        <property type="protein sequence ID" value="OBZ85637.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N970"/>
    <dbReference type="STRING" id="101091.A0A1C7N970"/>
    <dbReference type="InParanoid" id="A0A1C7N970"/>
    <dbReference type="OrthoDB" id="1661054at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017119">
        <property type="term" value="C:Golgi transport complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006891">
        <property type="term" value="P:intra-Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007255">
        <property type="entry name" value="COG8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016159">
        <property type="entry name" value="Cullin_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21311">
        <property type="entry name" value="CONSERVED OLIGOMERIC GOLGI COMPLEX COMPONENT 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21311:SF0">
        <property type="entry name" value="CONSERVED OLIGOMERIC GOLGI COMPLEX SUBUNIT 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04124">
        <property type="entry name" value="Dor1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74788">
        <property type="entry name" value="Cullin repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0653">Protein transport</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="548"/>
            <end position="587"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="604"/>
            <end position="785"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="9">
        <location>
            <begin position="89"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="548"/>
            <end position="560"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="568"/>
            <end position="583"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="604"/>
            <end position="622"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="643"/>
            <end position="654"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="655"/>
            <end position="690"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="700"/>
            <end position="749"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="753"/>
            <end position="765"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="10">
        <location>
            <begin position="772"/>
            <end position="785"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004395"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006419"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00020983"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00031347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="OBZ85637.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="785" mass="90095" checksum="6D2ABAD4545F0410" modified="2016-11-30" version="1">MTMSSQTAYEENNDDLLCLLTDAWENPLKETIKDARWIHDYLTRLTSLSLDQLLHEPLELRQEQANAIKDAQQLACHEYPLLLHAQTCRDTVEETMDELDGQLEQFIQSVPELEEACRVFEAHANTIKQERNKIVRLLEHQQVLTDVLEIPQLMETCVRNSYYSEAMDLASHVRLLSVRYPLPIIHSIQQQVQASSDRMLIQLISHLRKPVRLAAAMNMVGFLRRMDAFDSEAELRMVFLRCRHDYLQQRLLRIKRDLSDDTRQRGVDAFEYTKKFIDIMREQMFETGTQYVSIFPHEQGTLLSDYMVHVTQLIKSTLTTYLPMIEDTSSLASLLNQLQYCGMSLGRIGLDFRNIIVHLFEEALQPMLIRWINNAAEELKTTISKATLEGSLPSTWMASKTTSTTQTKRSAFQPPMLLVGYPSLAVFTNNILSVLNSLRLLPAISLCQPIISTLDSCFLFISVALQQYGDYVQKHMPDELVFLQSYAAAYAQCCVPYLESCLVDGIYGHLSMPKKHEDAVNLVLQAYLPVRVKEPIPSELDKELLSKDQQMLDSKSSSLEKVNEIKTSPENLNETNTNTNTSSDETDWEHMQATDEIVIANDMKGKASQEERSEVNEVKTDDLVTEETTASPEEKEQYPTQESTEEENNDGNEILEEKTRDDGNVLEEKINEAKDEVNEKEDEREIKADEQDFQQMTEPIEEKVKEEESKKIDEADNTKKNDEADNTKKNDEADNTKKNDEADNTKEIEEAPSTDNKQNQQNAKQTESKPKTNQKKKHKNKKGKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-06-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N991</accession>
    <name>A0A1C7N991_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_06750</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000422">
        <property type="protein sequence ID" value="OBZ85199.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N991"/>
    <dbReference type="InParanoid" id="A0A1C7N991"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ85199.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="87" mass="9877" checksum="CE0A4C3CBB5CB519" modified="2016-11-30" version="1">MQMMTAMHTEDSPNIASYLTTTAQCFIGTSDVCLNNVLLWRTPSPKMWISYSVVSHSSAFFHEHFLTFVIPSHLFGLDLADPIQRQN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N9V7</accession>
    <name>A0A1C7N9V7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="13">GTP-binding protein rhb1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">rhb1</name>
        <name evidence="13" type="ORF">A0J61_07816</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>GTP + H2O = GDP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:19669"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58189"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="12">
            <dbReference type="Rhea" id="RHEA:19670"/>
        </physiologicalReaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="11">Endomembrane system</location>
            <topology evidence="11">Lipid-anchor</topology>
            <orientation evidence="11">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the small GTPase superfamily. Rheb family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000551">
        <property type="protein sequence ID" value="OBZ84134.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N9V7"/>
    <dbReference type="FunCoup" id="A0A1C7N9V7">
        <property type="interactions" value="299"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N9V7"/>
    <dbReference type="InParanoid" id="A0A1C7N9V7"/>
    <dbReference type="OrthoDB" id="5976022at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04137">
        <property type="entry name" value="RheB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000273">
        <property type="entry name" value="GTP-binding protein Rheb homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001806">
        <property type="entry name" value="Small_GTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020849">
        <property type="entry name" value="Small_GTPase_Ras-type"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24070">
        <property type="entry name" value="RAS, DI-RAS, AND RHEB FAMILY MEMBERS OF SMALL GTPASE SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00071">
        <property type="entry name" value="Ras"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00449">
        <property type="entry name" value="RASTRNSFRMNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00175">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00173">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00174">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51419">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51421">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51420">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="5" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1" id="KW-0488">Methylation</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-0636">Prenylation</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023289"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00037969"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00046278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00049117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="OBZ84134.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="186" mass="20677" checksum="D15AA796E347871D" modified="2016-11-30" version="1">MSSANAKSRRIAVLGSRAVGKSSLVIQFCENHFVDSYYPTIENTFTKTIKYRGNEYSVEIMDTAGQDEYSILSSHHATSMNGYVLVYSIASRSSFDMIKIIRDKILDFTGLESVPCVIVGNKSDLNIQRQVTVEEGKELAQQWNCPTIETSAKHDENVSKIFDLLIAQIENANKPPTEEKGGCVIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NAU8</accession>
    <name>A0A1C7NAU8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Proline iminopeptidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">pip</name>
        <name evidence="4" type="ORF">A0J61_06107</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S33 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000352">
        <property type="protein sequence ID" value="OBZ85849.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NAU8"/>
    <dbReference type="STRING" id="101091.A0A1C7NAU8"/>
    <dbReference type="InParanoid" id="A0A1C7NAU8"/>
    <dbReference type="OrthoDB" id="1898734at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002410">
        <property type="entry name" value="Peptidase_S33"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051601">
        <property type="entry name" value="Serine_prot/Carboxylest_S33"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43248">
        <property type="entry name" value="2-SUCCINYL-6-HYDROXY-2,4-CYCLOHEXADIENE-1-CARBOXYLATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43248:SF2">
        <property type="entry name" value="PROLYL AMINOPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00793">
        <property type="entry name" value="PROAMNOPTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="3">
        <location>
            <begin position="60"/>
            <end position="221"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010088"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OBZ85849.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="459" mass="52433" checksum="E36A3C857963FF89" modified="2016-11-30" version="1">MHPLDSSVESFSIPGAQVFERYFECPLDYANETTSSKIRVFVRHLVPIEKVSLMKKMPFFLYLQGGPGFECALPSSGTSGWVKVAFERGYQVLLLDQRGTGLSSQISTESLDQLFKTDEEKAEYLAHFRADNIVRDCEHIRKELTAGRSSDEESRISLLGQSFGGFCITTYLSLFPDSIQEAYITGGVPPLSDNPDQVYRALYPRIAKKNTLYYKKFPRDVARVRQIHDYLSSNKVILPNGGCLSERRFLQLGLMFGGSGGYDAVHIAVQSAAEDLDRLGRLSYRTLNMIQSMQSWDTNVIYAILHEAIYCQSNQSSRWSAERLLKEEPFCTTFEWRSENLKKDQPVFFTGETIYPFMFEDYAELRPLKQVAHLLAEKQWTSLYDVQTLNKLKGVCVAGVSYFDDMYVDRELSEQTAAEINGFQQWITNEYAHNGLRVDGERILNYLVKLARGDESFNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NB12</accession>
    <name>A0A1C7NB12_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Methyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_07414</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000499">
        <property type="protein sequence ID" value="OBZ84534.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NB12"/>
    <dbReference type="FunCoup" id="A0A1C7NB12">
        <property type="interactions" value="432"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NB12"/>
    <dbReference type="InParanoid" id="A0A1C7NB12"/>
    <dbReference type="OrthoDB" id="2013972at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041698">
        <property type="entry name" value="Methyltransf_25"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43591:SF24">
        <property type="entry name" value="2-METHOXY-6-POLYPRENYL-1,4-BENZOQUINOL METHYLASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43591">
        <property type="entry name" value="METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13649">
        <property type="entry name" value="Methyltransf_25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Methyltransferase" evidence="2">
        <location>
            <begin position="202"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="74"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="95"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="128"/>
            <end position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ84534.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="463" mass="52533" checksum="977E7E65E0BE331E" modified="2016-11-30" version="1">MGQPQSSVTMDTPKSYPTRDPQSTTKRPPVKKLPPPNMGSFFDAQMAAPLPHAHVRKPNRPKNDFNFYFESASVTPQPATSTNSRSHNSSKKKSSSSSYGSSYKNCTRTTASSSSTSSTASSTLINEQNEKQDKTDQKANHIIIQGRRYWRGHASHNFYLPHDDDESDRLMNLHYILKSIFQGNFTAPVNRLLEQTTKKAKVLDIGCGAGTWVLEMATEYPQAEFIGIDEYPGFPTHIKPSNSRFVAHNVLKGLPFEDKTFDFVYMRMMIIYFTPEKLSYLLSEINRVMKHGAYLEIVDTNYTVRHAGPLTTKAINQDLKFILYSGSLAQRMIQQDLATNHPIFNYLLMASSSPQQPATSFIGNFIDICQDYVSLPLGWNDNQVCALHTKNFESFLRGLRPRDPEALALTQHVIDDVMDECERFKSQLDWFSCYARKPAMETEEIDQNTLESIHEFVEGFVDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NBE7</accession>
    <name>A0A1C7NBE7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_07287</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000484">
        <property type="protein sequence ID" value="OBZ84664.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NBE7"/>
    <dbReference type="InParanoid" id="A0A1C7NBE7"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ84664.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="96" mass="10723" checksum="AFF5A712D02B1CFD" modified="2016-11-30" version="1">MQVGAETSKSLQAFLVLKWYMRLVFDKDRSKKKSTKSKRTYQKSNVVEEFEALKENLAENAVSAATTLIYAIGTEIVAAAGIRPALRLILVKGFKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NBI2</accession>
    <name>A0A1C7NBI2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Plasma membrane fusion protein PRM1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">PRM1</name>
        <name evidence="11" type="ORF">A0J61_05952</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 10">Involved in cell fusion during mating by stabilizing the plasma membrane fusion event.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cell envelope</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="10">Cell membrane</location>
            <topology evidence="10">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Endomembrane system</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 10">Belongs to the PRM1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000338">
        <property type="protein sequence ID" value="OBZ85996.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NBI2"/>
    <dbReference type="FunCoup" id="A0A1C7NBI2">
        <property type="interactions" value="3"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NBI2"/>
    <dbReference type="InParanoid" id="A0A1C7NBI2"/>
    <dbReference type="OrthoDB" id="10248838at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043332">
        <property type="term" value="C:mating projection tip"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032220">
        <property type="term" value="P:plasma membrane fusion involved in cytogamy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026777">
        <property type="entry name" value="PRM1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31030">
        <property type="entry name" value="PLASMA MEMBRANE FUSION PROTEIN PRM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31030:SF1">
        <property type="entry name" value="PLASMA MEMBRANE FUSION PROTEIN PRM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 10" id="KW-0184">Conjugation</keyword>
    <keyword evidence="9" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="12"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="244"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="332"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="519"/>
            <end position="540"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002512"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004196"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010780"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU366035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="OBZ85996.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="544" mass="61167" checksum="3CA55C487AF7B1D5" modified="2016-11-30" version="1">MSDAMRSISMSYSYAWVQISAIVIGTIIGSLFYMVKQIGSSVESVKLKAESACDIVDATATQLYNMPQLQLESAIQSIYTTKENIHKTLIVITSSVEKCIVWLSGFYKSTYRCLLGVAIHTVLELVKQVVGPVQTVASGIASFFHVDDTSINNIQWFQALNDVQGKIDQWFQKDDVLLEQVIHKPFSLLQSQINSTIGSWNPPPFHLNQIERNVSAQFLLRQPCDTDELVHSLDYAYHNLAKQIYILVGVLFGLLLVCGIANLTVARLRHRQVMQARTIFLKLASELPEKGYDLTSLLDEYTWNTNYLSPFVSWKTYNKPVYRVLSVLMHPGSICCLFVAISGILMVHFLCWLLIARSEQAFTAFNDQAHQWALGMTSEWSINANSQINEINEWINQTEYHLNNNMLSVIQGSAVALNGTLSHVVDQIGELISNILGGTVLETSAKQLAQCLVVEKIENIEAGLTWIADVTFVHLGRINSSKADTSLFEEKMTKAIDNHMEATATQSFGVTNSLDHLMIFYYMLLAVWCAHTCISLVFHFRKKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NBW4</accession>
    <name>A0A1C7NBW4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Mediator complex subunit 15 KIX domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">A0J61_05356</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000287">
        <property type="protein sequence ID" value="OBZ86593.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NBW4"/>
    <dbReference type="STRING" id="101091.A0A1C7NBW4"/>
    <dbReference type="InParanoid" id="A0A1C7NBW4"/>
    <dbReference type="OrthoDB" id="1938591at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016592">
        <property type="term" value="C:mediator complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003712">
        <property type="term" value="F:transcription coregulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036546">
        <property type="entry name" value="MED15_KIX"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008626">
        <property type="entry name" value="Mediator_Med15_fun"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36721:SF1">
        <property type="entry name" value="OS04G0446401 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36721">
        <property type="entry name" value="PROLINE-RICH FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16987">
        <property type="entry name" value="KIX_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05397">
        <property type="entry name" value="Med15_fungi"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Mediator complex subunit 15 KIX" evidence="5">
        <location>
            <begin position="41"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="278"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="359"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="776"/>
            <end position="831"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="662"/>
            <end position="719"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="278"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="329"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="362"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="401"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="791"/>
            <end position="800"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="810"/>
            <end position="822"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="831"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF16987"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OBZ86593.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="831" mass="92834" checksum="241E4388BCF073B4" modified="2016-11-30" version="1" fragment="single">MNQQNPNQQIPSGQPPPSQPQQMLQQQQVNLGHPNDIPNANWRTEVSVPDRSLFVSQLSLALKHLSPATPESETYNVASNFEAGLYKRCSSKNEYVLAYARKFQQIKEQINQQNTAMMNANPMLQPMSPLNTNNNGQVTSSPQRHNFQASLDLNQPPSQLVPGQNQIRPTVQQTNFAHSLQQGRPPQQVMQSPAQAQMFAYQRSAAAAAAAAAAAMAASNTPQMMPQQRGPQPQQQIPMNLLNATNAANPNNANQAGLGITSQQFQMYFARQMALQQQQQLQQPQQSSQPSQTQATSQPSSSSYSPHMQNPMLQPPQPQPQSSPVQQQGFLPQGNNSSMIGMTQQQLMNMGLVSKPMMTGVNYRSQPSSTQPQVPFSQPDNTNNSLGSPLQQNMNYPNTMGSGSASSTPVTASATLPTTTTTTTSNTTTGVNTNTSTMAGTNTHMAQVAAQAAIQPFHMRPNNTTGPNQELLMQRLQQQNMMVPRPPMMQQTPQPFVPPQMQRPLMNSQPQMQTMMKPVTPQQRNQAANIVRQIDESVRQGRVRGALIEDMSEEDKNAIREQIGQTKQMYDKIDNLLPVFLAMTGNVEATRRLVMMKYMFEDQLNALPHNKFIISLENLQKLRDQFNGYFTWVRNAVGQQQQQMNVMNQQNQIGLGLLPMHLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQGSPLVHYNQLGQQGMLPQQQNAMHQMQAMSQTQAMNQAQAMSQSQAQALAMLRQQQQLQAQQQESPAMVPATTTTTTNTTTKSAENTPIMTHSTANTTPTTPSLGIKRGSID</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NC20</accession>
    <name>A0A1C7NC20_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_05433</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000292">
        <property type="protein sequence ID" value="OBZ86520.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NC20"/>
    <dbReference type="STRING" id="101091.A0A1C7NC20"/>
    <dbReference type="InParanoid" id="A0A1C7NC20"/>
    <dbReference type="OrthoDB" id="2287217at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008889610" evidence="2">
        <location>
            <begin position="24"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="230"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="307"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="383"/>
            <end position="411"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ86520.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="422" mass="44851" checksum="D4F695EB52981F89" modified="2016-11-30" version="1">MKTKNIFTAITVTAASLLACVETVDNRQFRIDVYPEDTSNSQVRLCLSVNGCQYLCNSFFDGEENTIARIDVNNCSNQDDYEPAVVFPKKGSVTVPGVLFGEDSGGPIRCTLAGRDPLDAHQYYYCPPKSISETSTSSISTATATTIEEPITVVDISTDTTTQKSTMTGTTTTTITTEEPTTATTITNWPTATITTDVVTKEPTKTTATSTKEPTTTTTITTKEPTITTTTAAATATTTTNTTSTKEPTTTTTTKEPTTTTSTKEPTTTTTTKEPTTTTTTKEPTTTTTKKSTMTTKKSTATTKKSTTSTKKSTTSTKKSTTSTKKSTMTTKKSTTATKKSTTTIKKPTMTTKKSTTTIKKSTTATKKPTTTIKKSTITVKSSATSSCIPGYSGKKKGNGPKSACCSSKSDCKDSCVKEKCT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NCQ7</accession>
    <name>A0A1C7NCQ7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">A0J61_05071</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the cytochrome c oxidase VIIa family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000264">
        <property type="protein sequence ID" value="OBZ86875.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NCQ7"/>
    <dbReference type="STRING" id="101091.A0A1C7NCQ7"/>
    <dbReference type="InParanoid" id="A0A1C7NCQ7"/>
    <dbReference type="OrthoDB" id="5511599at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045277">
        <property type="term" value="C:respiratory chain complex IV"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006123">
        <property type="term" value="P:mitochondrial electron transport, cytochrome c to oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.91.10">
        <property type="entry name" value="Cytochrome c oxidase, subunit VIIa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039297">
        <property type="entry name" value="COX7a"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036539">
        <property type="entry name" value="Cyt_c_oxidase_su7a_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02238">
        <property type="entry name" value="COX7a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81419">
        <property type="entry name" value="Mitochondrial cytochrome c oxidase subunit VIIa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="3" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="34"/>
            <end position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009331"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OBZ86875.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="75" mass="8455" checksum="0F1FF9490C39AC29" modified="2016-11-30" version="1">MSLVNRPNNVQAYQKFYQAPSNTLLFLRGPRDKLFVYSTFAVLGAGLLGSLYGAVNMARVCIKTFFFDSLARRTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7ND23</accession>
    <name>A0A1C7ND23_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="11">SWI/SNF and RSC complexes subunit ssr2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">ssr2_0</name>
        <name evidence="11" type="ORF">A0J61_04948</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the SMARCC family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000254">
        <property type="protein sequence ID" value="OBZ87007.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7ND23"/>
    <dbReference type="STRING" id="101091.A0A1C7ND23"/>
    <dbReference type="InParanoid" id="A0A1C7ND23"/>
    <dbReference type="OrthoDB" id="118550at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016514">
        <property type="term" value="C:SWI/SNF complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048858">
        <property type="term" value="P:cell projection morphogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd00167">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.10:FF:000020">
        <property type="entry name" value="SWI/SNF complex subunit SMARCC2 isoform c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.60:FF:000014">
        <property type="entry name" value="SWI/SNF complex subunit SMARCC2 isoform C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10190">
        <property type="entry name" value="BRCT domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036420">
        <property type="entry name" value="BRCT_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049898">
        <property type="entry name" value="MARR_BRCT_CHROMO"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017930">
        <property type="entry name" value="Myb_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001005">
        <property type="entry name" value="SANT/Myb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017884">
        <property type="entry name" value="SANT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007526">
        <property type="entry name" value="SWIRM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15381:SF1">
        <property type="entry name" value="CHONDROITIN SULFATE PROTEOGLYCAN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15381">
        <property type="entry name" value="CHONDROITIN SULFATE PROTEOGLYCAN 5 -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00249">
        <property type="entry name" value="Myb_DNA-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04433">
        <property type="entry name" value="SWIRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00717">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52113">
        <property type="entry name" value="BRCT domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51294">
        <property type="entry name" value="HTH_MYB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52032">
        <property type="entry name" value="MARR_BRCT_CHROMO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50090">
        <property type="entry name" value="MYB_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51293">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50934">
        <property type="entry name" value="SWIRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Chromo" evidence="10">
        <location>
            <begin position="1"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="domain" description="SWIRM" evidence="7">
        <location>
            <begin position="323"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="domain" description="HTH myb-type" evidence="9">
        <location>
            <begin position="536"/>
            <end position="592"/>
        </location>
    </feature>
    <feature type="domain" description="SANT" evidence="8">
        <location>
            <begin position="539"/>
            <end position="590"/>
        </location>
    </feature>
    <feature type="domain" description="Myb-like" evidence="6">
        <location>
            <begin position="543"/>
            <end position="586"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="439"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="626"/>
            <end position="647"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="709"/>
            <end position="764"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="451"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="711"/>
            <end position="764"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00049655"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50934"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51293"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS52032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="OBZ87007.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="764" mass="89128" checksum="036C08D9207D3419" modified="2016-11-30" version="1">MSAPPKKPSIDIEYYEQPKVIGYFESIIDPLRIELDKAGCDTHITTPDLGYFTAHFQKFQLHHLKKQHETYIPFAYFNVVSLSTQSPLYHILKSAYRFKSERQIVDWRWDAPEETETYLHMIQVIKEDLDKAGFELCKPRIWFHETSAEEQKKKRHHYSNHQGQLNHWHALVEQLGGIVVDTMEEATFIVYHHEQTFDRYHRNWRMLHQTDEEAMVHWIGLPDSYNTLVKLNQCVLDKEETTDLAEDNQCAPWHVKSNWIDDSAKYNEWMSPLDYVMSAQQSLKRKLVVMEETNNKKVKTAEERKQKTWAMARQYMPIQQYEVIIPSYAAWFDLETIHPIETKGLPEFFNQKNKSKTPSIYKEYRDIMINTYRLNPMEYLTVTACRRNMAGDVCAIIRVHGFLEQWGLINYQMDPSAKPTAIGPPLEGQVKVIAEFPKGMAYPSSPPSTPPSTTATPSATTTTDTPSSPSTATPSITPSLETTKAPSNIDLNLDLRQDIYKKNTFCHVCKKEKKKGYMSTKQFICDDCYQPEQHKEFTKRLTPWTDQEDMLLLEGLEMFSEDWQKIAEHVGTKTRDECILHYLQLPLLDPVYATDQHQHNDMENPIMSVVAFLAANVKPKVAASILASDETKENQQEKEEDIEEDTHEEKFRLIRTKMKAYSARISQFEKLEGWVDSEKRQLEKGRCLIQSQHVAIRKQIDEIRHLMFQKQQTQPQPQSQEQSQQPQQPQLEQQPLPQQLQEQSQQLPQQLPQIQPQQPDSHSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7ND61</accession>
    <name>A0A1C7ND61_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">alpha-L-fucosidase</fullName>
            <ecNumber evidence="3">3.2.1.51</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">Fuca2</name>
        <name evidence="10" type="ORF">A0J61_04906</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Alpha-L-fucosidase is responsible for hydrolyzing the alpha-1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the glycosyl hydrolase 29 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.51" evidence="3"/>
    <dbReference type="EMBL" id="LUGH01000251">
        <property type="protein sequence ID" value="OBZ87043.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7ND61"/>
    <dbReference type="STRING" id="101091.A0A1C7ND61"/>
    <dbReference type="InParanoid" id="A0A1C7ND61"/>
    <dbReference type="OrthoDB" id="6039950at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004560">
        <property type="term" value="F:alpha-L-fucosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006004">
        <property type="term" value="P:fucose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016139">
        <property type="term" value="P:glycoside catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1180">
        <property type="entry name" value="Golgi alpha-mannosidase II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016286">
        <property type="entry name" value="FUC_metazoa-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031919">
        <property type="entry name" value="Fucosidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000933">
        <property type="entry name" value="Glyco_hydro_29"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057739">
        <property type="entry name" value="Glyco_hydro_29_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013780">
        <property type="entry name" value="Glyco_hydro_b"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10030">
        <property type="entry name" value="ALPHA-L-FUCOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10030:SF37">
        <property type="entry name" value="ALPHA-L-FUCOSIDASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01120">
        <property type="entry name" value="Alpha_L_fucos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16757">
        <property type="entry name" value="Fucosidase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00741">
        <property type="entry name" value="GLHYDRLASE29"/>
    </dbReference>
    <dbReference type="SMART" id="SM00812">
        <property type="entry name" value="Alpha_L_fucos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008889631" description="alpha-L-fucosidase" evidence="7">
        <location>
            <begin position="19"/>
            <end position="764"/>
        </location>
    </feature>
    <feature type="domain" description="Glycoside hydrolase family 29 N-terminal" evidence="8">
        <location>
            <begin position="313"/>
            <end position="658"/>
        </location>
    </feature>
    <feature type="domain" description="Alpha-L-fucosidase C-terminal" evidence="9">
        <location>
            <begin position="681"/>
            <end position="761"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007951"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012662"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01120"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF16757"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OBZ87043.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="764" mass="86528" checksum="F9963EB5F806DF93" modified="2016-11-30" version="1">MILSISFWALLLIGYVLALENLKDTQYQIQLESFFNNKGGSGPGSNLDGANNYFDCPALKSSNLTIGNIDFHLSTSEENDNVVSQAQIIPLGAPFLGAIYLLSAVNHGPLTSDIIVVYQDGTYSTTTLNLPDWQVSHSQQIDRLDHIACSLHHGANAYLFLTPVFVDPTKRVAHIRLPSTNAIGSFGPSLHIFGITTIPAKPSGLTVVAAKGTRRWKQSHDGKRSYQIITVRVHNTSPTWIQDANVHITGAFIRTHYFGIIARLAPGHILNIDVAVSTLRKDRGRQDILVDVIDSSDNQIALTTLFKDIKVGLEDYEPTEASLQTHSAPAWYQAAKFGIFIHWGVYSVPSWAPVGADYAEWYWWNYNQKNSATYQYHRTFYGPDVEYDDFIQAWHPDQFDPIRWLETIDSSGAKYFVFTTKHHDGIALFDTKVSNRSSVQLNPHRDFVKELFDAAEKHYPHLKRGVYFSLPEWYHPDYRDDSIHWNGPPVNPYTGKTVPYTGGQRVSDFVNDIQVPQFLELIQQFEPDIMWCDIGAINNSTAWQAKFLNSARNQGRDVTFNDRCGNGVSDFATVEYNDVNYVPSRYWESTRGIDPHSFGYNHQTKDQQYASTASLLQELVSTVAKGGNFLLNIGPEGSGHIPHVMKKTLNQMGQWLDTVDESVFQSIPYWVTSLDFHEPGQQLYFTQSNNGKAFYIFCLNRPVDERLVIKSPVPLHSKSHISLLNSKTFSLSWRIFGDGKLVIHVPNELLDREKWIWVFKIDHT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7ND86</accession>
    <name>A0A1C7ND86_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">3-hydroxyisobutyryl-CoA hydrolase</fullName>
            <ecNumber evidence="2">3.1.2.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">hibch_0</name>
        <name evidence="5" type="ORF">A0J61_04877</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>3-hydroxy-2-methylpropanoyl-CoA + H2O = 3-hydroxy-2-methylpropanoate + CoA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:20888"/>
            <dbReference type="ChEBI" id="CHEBI:11805"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57340"/>
            <dbReference type="EC" id="3.1.2.4"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.2.4" evidence="2"/>
    <dbReference type="EMBL" id="LUGH01000249">
        <property type="protein sequence ID" value="OBZ87067.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7ND86"/>
    <dbReference type="FunCoup" id="A0A1C7ND86">
        <property type="interactions" value="413"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7ND86"/>
    <dbReference type="InParanoid" id="A0A1C7ND86"/>
    <dbReference type="OrthoDB" id="1737613at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003860">
        <property type="term" value="F:3-hydroxyisobutyryl-CoA hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006574">
        <property type="term" value="P:L-valine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06558">
        <property type="entry name" value="crotonase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.226.10">
        <property type="entry name" value="2-enoyl-CoA Hydratase, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045004">
        <property type="entry name" value="ECH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032259">
        <property type="entry name" value="HIBYL-CoA-H"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF004127">
        <property type="entry name" value="PRK05617.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43176:SF3">
        <property type="entry name" value="3-HYDROXYISOBUTYRYL-COA HYDROLASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43176">
        <property type="entry name" value="3-HYDROXYISOBUTYRYL-COA HYDROLASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16113">
        <property type="entry name" value="ECH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="ClpP/crotonase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Enoyl-CoA hydratase/isomerase" evidence="4">
        <location>
            <begin position="51"/>
            <end position="379"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001709"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011915"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF16113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OBZ87067.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="474" mass="53521" checksum="39287E14AAD8BE0B" modified="2016-11-30" version="1">MHRLSLIGKRPILLGHLNRPLCRSISVACHQTLEDELPETYVLHRKVSGARMFILNRPEKLNALNLGMIRNIGPQLKAWDVSSLAKVILLKGAGKGKLSVGDDILDILLKAQAKDPDALYFFQDKFGLVQMIATLKTPYVAILDGYALGGALGLFVHGPFRIATEKTIFAVPEVSIGAFLNSGSSFFLSRLDGQIGTYLALTGSRLEGIDAFFAGIATHYVPSSRIQALEQKLIDLDISEHEIIQRVLENFVEPKPVEKIGFQKDTRQIIDRCFAFNTIEEIIAALDKEKQTSWIRETKQKLLSVSPTSLKVTLKALRKGKSMSLVECLKMEFDLIQKFLVTRDFHEGVEASFTSKPRRKPQWQPSQLAGVTEEDVEQLYFSDPSPNVLSLPTKLDLKRYPYARFALPTEEEVRLAITGEGAEFRTEGRLKEDEEILSWFQKGHKGKWGVREKVMDILSRKTILKDQKDREWLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-06-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NDM4</accession>
    <name>A0A1C7NDM4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_04752</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000239">
        <property type="protein sequence ID" value="OBZ87197.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NDM4"/>
    <dbReference type="InParanoid" id="A0A1C7NDM4"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ87197.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="76" mass="9071" checksum="CF56482F0DA40C03" modified="2016-11-30" version="1">MYRSQKVDRTMSATALVSGSFILVSNYQHYLAYIPEMLRFAYYNKRAQLSGKSFFMYLYHKNRHLSPKLFVIIDLH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NDP1</accession>
    <name>A0A1C7NDP1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Putative GTP-binding protein EngB</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">engB_1</name>
        <name evidence="8" type="ORF">A0J61_05282</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000281">
        <property type="protein sequence ID" value="OBZ86676.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NDP1"/>
    <dbReference type="STRING" id="101091.A0A1C7NDP1"/>
    <dbReference type="InParanoid" id="A0A1C7NDP1"/>
    <dbReference type="OrthoDB" id="391988at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01876">
        <property type="entry name" value="YihA_EngB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00321">
        <property type="entry name" value="GTPase_EngB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030393">
        <property type="entry name" value="G_ENGB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006073">
        <property type="entry name" value="GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019987">
        <property type="entry name" value="GTP-bd_ribosome_bio_YsxC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR03598">
        <property type="entry name" value="GTPase_YsxC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47560">
        <property type="entry name" value="EXPRESSED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47560:SF1">
        <property type="entry name" value="EXPRESSED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01926">
        <property type="entry name" value="MMR_HSR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51706">
        <property type="entry name" value="G_ENGB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="5" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="EngB-type G" evidence="7">
        <location>
            <begin position="118"/>
            <end position="292"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009638"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51706"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OBZ86676.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="323" mass="36955" checksum="52ADE850EFDA2F5F" modified="2016-11-30" version="1">MQASRLLRSCQPIKPNVQFFVRSFVTATSETSSTLSNRQKFNMIQPPIKLYEKLERLGFGTLLKTKRYSGLHKQRAKREAKTLKYTEKKEVEKEPSYNFPLLSFYAGAKTPSSFPKESLDEIAFVGRSNVGKSSLINSLAESSTVRTSNKPGLTQQLNFYNVGRLFSIVDMPGYGFAFADEEEREQWKTLIETYITQRKTLKRVYVVLDGRHGVKIADIEFFKMLNSKRVKFQVVLTKCDLLVLPNLARRVVTVEDHIKTLPNAVKDVVIVSSKSGAGINQFRKEVLFLMNHLQPKSFYKALELEKAEKIAKAEKAQRKREGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NDU8</accession>
    <name>A0A1C7NDU8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Putative NADH-ubiquinone oxidoreductase 30 subunit, mitochondrial</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">ALI1</name>
        <name evidence="11" type="ORF">A0J61_04823</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>a ubiquinone + NADH + 5 H(+)(in) = a ubiquinol + NAD(+) + 4 H(+)(out)</text>
            <dbReference type="Rhea" id="RHEA:29091"/>
            <dbReference type="Rhea" id="RHEA-COMP:9565"/>
            <dbReference type="Rhea" id="RHEA-COMP:9566"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16389"/>
            <dbReference type="ChEBI" id="CHEBI:17976"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="7.1.1.2"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the complex I 30 kDa subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000244">
        <property type="protein sequence ID" value="OBZ87130.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NDU8"/>
    <dbReference type="STRING" id="101091.A0A1C7NDU8"/>
    <dbReference type="InParanoid" id="A0A1C7NDU8"/>
    <dbReference type="OrthoDB" id="37721at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008137">
        <property type="term" value="F:NADH dehydrogenase (ubiquinone) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016651">
        <property type="term" value="F:oxidoreductase activity, acting on NAD(P)H"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.460.80:FF:000002">
        <property type="entry name" value="NADH dehydrogenase iron-sulfur protein 3, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.460.80">
        <property type="entry name" value="NADH:ubiquinone oxidoreductase, 30kDa subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01357">
        <property type="entry name" value="NDH1_NuoC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010218">
        <property type="entry name" value="NADH_DH_suC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037232">
        <property type="entry name" value="NADH_quin_OxRdtase_su_C/D-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001268">
        <property type="entry name" value="NADH_UbQ_OxRdtase_30kDa_su"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020396">
        <property type="entry name" value="NADH_UbQ_OxRdtase_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01961">
        <property type="entry name" value="NuoC_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF004733">
        <property type="entry name" value="PRK06074.1-5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10884:SF14">
        <property type="entry name" value="NADH DEHYDROGENASE [UBIQUINONE] IRON-SULFUR PROTEIN 3, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10884">
        <property type="entry name" value="NADH DEHYDROGENASE UBIQUINONE IRON-SULFUR PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00329">
        <property type="entry name" value="Complex1_30kDa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143243">
        <property type="entry name" value="Nqo5-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00542">
        <property type="entry name" value="COMPLEX1_30K"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8" id="KW-0520">NAD</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-1278">Translocase</keyword>
    <keyword evidence="3 8" id="KW-0813">Transport</keyword>
    <keyword evidence="6 11" id="KW-0830">Ubiquinone</keyword>
    <feature type="domain" description="NADH:ubiquinone oxidoreductase 30kDa subunit" evidence="10">
        <location>
            <begin position="86"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="235"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="246"/>
            <end position="261"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00049551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003456"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="OBZ87130.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="261" mass="29928" checksum="4DFB0922CAD6DDFA" modified="2016-11-30" version="1">MASRLISASLMRLPRTMPAVRQTAVRSFATTSVSLQAAEKKNYNKVSADPNFKSGNDDLHEYGKYLMSVMPKFIQQFSVYKDELTIYIAPTAVTPVMTFLRDHTNAQFKSVMDITAADYPTRDNRFEVVYNMLSMKYNGRIRVKTYASEISPVPSVVPLFSGANWQERETYDMFGVFFTGHPDLRRILTDYGFEGHPLRKDFPLTGYVEVRYDEEKKRVVSEPVELAQAFRNFEGALSPWEQNGPGRDDTPKQIESEEKKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NE92</accession>
    <name>A0A1C7NE92_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Protein transport protein sec73</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">sec73</name>
        <name evidence="5" type="ORF">A0J61_04695</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000235">
        <property type="protein sequence ID" value="OBZ87260.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NE92"/>
    <dbReference type="STRING" id="101091.A0A1C7NE92"/>
    <dbReference type="InParanoid" id="A0A1C7NE92"/>
    <dbReference type="OrthoDB" id="430364at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005085">
        <property type="term" value="F:guanyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032012">
        <property type="term" value="P:regulation of ARF protein signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1000.11:FF:000002">
        <property type="entry name" value="Cytohesin 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1000.11">
        <property type="entry name" value="Arf Nucleotide-binding Site Opener,domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041681">
        <property type="entry name" value="PH_9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001849">
        <property type="entry name" value="PH_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023394">
        <property type="entry name" value="Sec7_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000904">
        <property type="entry name" value="Sec7_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035999">
        <property type="entry name" value="Sec7_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10663:SF405">
        <property type="entry name" value="ARF GUANINE NUCLEOTIDE EXCHANGE FACTOR SYT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10663">
        <property type="entry name" value="GUANYL-NUCLEOTIDE EXCHANGE FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15410">
        <property type="entry name" value="PH_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01369">
        <property type="entry name" value="Sec7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00233">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00222">
        <property type="entry name" value="Sec7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48425">
        <property type="entry name" value="Sec7 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50003">
        <property type="entry name" value="PH_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50190">
        <property type="entry name" value="SEC7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SEC7" evidence="4">
        <location>
            <begin position="17"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="domain" description="PH" evidence="3">
        <location>
            <begin position="231"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="540"/>
            <end position="583"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="373"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="555"/>
            <end position="569"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OBZ87260.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="612" mass="69821" checksum="25598A34A362263A" modified="2016-11-30" version="1">MVTTTDEQTEANFASQVQQFDFCGESIDASLRKLLAKVHLPKEAQQIDRAMEDFAKQYYECNPGLVDSPDAVYAVAFSILLLHTDAHNKNVRQKMNKDTFIMRTKIIEGGEGFPHEILDIIYDNIVMSEFTYADHPQSTRNHSWFSKLKSTASTTDLHSQTNTNPWMIDLAQKLEQLMPAENSYSYKRTLKPIPIMEIHLSLLKAKSLCLAGVKSRQDTSDQSSNSTFQVRVTKAGILDRKYDLLQGGKKATARGWRPLGVILSGSQIIFFADLVAYQQWLETGSPTNSSFHSLSSNIPTPAYLRPVQIISLSYAVCICDEQYTKYPHVFRLIVGDGQQFLMRAEDDQDMEDWMLKINYAATIKTTGVRLQSKSKESRREERARAKVDELSDRIDEQVRLLDRELQLRRNLMVFVPQQKSTKDRILSFSDAVGKRIKMKRIELQRLECYRDFLEAELSWYQSTYPTRKMSLPLPTHLCSFVQPQGKENKKLSNLVFTAPDIQEEEGSDEEQHINSQPPVLPTFSFPRPLVETVPFTTATDRVTRRRSQSNPVRPVLDKKVLLEPPPEHKARCRSGSVASSVQEDDSMSVVIINESEELLEPVTDVWHDAASQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NEA5</accession>
    <name>A0A1C7NEA5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Transcription activator GCR1-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_04678</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000233">
        <property type="protein sequence ID" value="OBZ87280.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="InParanoid" id="A0A1C7NEA5"/>
    <dbReference type="OrthoDB" id="2287578at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0060963">
        <property type="term" value="P:positive regulation of ribosomal protein gene transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052146">
        <property type="entry name" value="HOT1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022210">
        <property type="entry name" value="TF_GCR1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37784:SF2">
        <property type="entry name" value="HIGH-OSMOLARITY-INDUCED TRANSCRIPTION PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37784">
        <property type="entry name" value="PROTEIN MSN1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12550">
        <property type="entry name" value="GCR1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Transcription activator GCR1-like" evidence="2">
        <location>
            <begin position="100"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="46"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="55"/>
            <end position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12550"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ87280.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="144" mass="15798" checksum="12D3AB595D9FEA9F" modified="2016-11-30" version="1">MTQQWNRIVSEGATLNVRLNMPESSQQAELSTASLSSNITVPSVASNPPILQRESSPSIXXSSSXIXXAXQPTQTAPXSHSIQTAPVTSGSLELNIKAFRNVKTLSALWRLWFEGLPGHHPICKLDEVYGVKSWRRTSSDSKIY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NEJ4</accession>
    <name>A0A1C7NEJ4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Protein Hook 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">hook3</name>
        <name evidence="10" type="ORF">A0J61_04413</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the hook family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000215">
        <property type="protein sequence ID" value="OBZ87543.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NEJ4"/>
    <dbReference type="STRING" id="101091.A0A1C7NEJ4"/>
    <dbReference type="InParanoid" id="A0A1C7NEJ4"/>
    <dbReference type="OrthoDB" id="49395at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005815">
        <property type="term" value="C:microtubule organizing center"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051959">
        <property type="term" value="F:dynein light intermediate chain binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008017">
        <property type="term" value="F:microtubule binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031122">
        <property type="term" value="P:cytoplasmic microtubule organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030705">
        <property type="term" value="P:cytoskeleton-dependent intracellular transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd22211">
        <property type="entry name" value="HkD_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.418.10">
        <property type="entry name" value="Calponin-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001715">
        <property type="entry name" value="CH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036872">
        <property type="entry name" value="CH_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008636">
        <property type="entry name" value="Hook_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043936">
        <property type="entry name" value="HOOK_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18947:SF28">
        <property type="entry name" value="GIRDIN, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18947">
        <property type="entry name" value="HOOK PROTEINS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05622">
        <property type="entry name" value="HOOK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19047">
        <property type="entry name" value="HOOK_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF116907">
        <property type="entry name" value="Hook domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50021">
        <property type="entry name" value="CH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="4" id="KW-0493">Microtubule</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Calponin-homology (CH)" evidence="9">
        <location>
            <begin position="9"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="772"/>
            <end position="800"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="186"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="473"/>
            <end position="500"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="555"/>
            <end position="630"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="674"/>
            <end position="701"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="725"/>
            <end position="759"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="774"/>
            <end position="790"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="791"/>
            <end position="800"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50021"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OBZ87543.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="800" mass="94223" checksum="0312A3757E68F3C5" modified="2016-11-30" version="1">MMRMAESEGGPAAAVVQWVNSFESVSNPVSRIQDLSDGIALFEVVSHIDYKWFKLIRSTDVGDNWVLKINNLKKLYKLIDRYYEEKLGISFKRLPEVNLNAIAKDANATEIIQLCKYVLYIAVCCPDNTQYIQSITQLNSVSQENLMFFIDEVMRYTKEDQPMTSQQTSSQYTQMNDFGDDNYSEMTRIMRQNEELELQNKQLIDKHSELLTRYDRLENEKQDLQARLKDMDTAVAQANETGRADFIMRTEIDHLKQDLQRSEDTRQEQERQLDQHTFQINDLTRRNEELTRQAELAARLKDQLDEHRHVAEKLQKAENVIEKYKKKLDETADLRRQVKALEDQNHSLMERNQKIEDEYRNVLAFKTLMDSYKDQVATLETKNNEIMREKNKIEYELVQATKKLELMEADRERDYDRIQALEENLQEAQLGIGSIIDRPSANKTTSDTDDMMEIEDEFHINDSLEDTLKESNVTELKLSKRRLERQLKTLQEENAQGRNQKVVVLQHLLDDANRLKTQFEKSYLEVSQERDILQSDMARIREGIPDALADQNKNTLSLRLRIIELEKDVKSLNEQIKKLEQKISESRLMDESENVPGDFKVKYNEMETRCKQLEEQTRKQLQDINKLLLEKDLLQGQSIEQKDLLLEKERMTSEMKATLAAFEAKGDEPFKQLNAQMQQQMIQLQEELHVFKARHKKAKELIKRQDKMIKEGLVEANGNNYSEAISSMKTEIVMREEEIEKLKKLLQETRLQSRREQQLMISAWYDMSKRVNKETSSQKAFPNSWLAQQRRSLDNKVKRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NEU4</accession>
    <name>A0A1C7NEU4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_04348</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000211">
        <property type="protein sequence ID" value="OBZ87597.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NEU4"/>
    <dbReference type="STRING" id="101091.A0A1C7NEU4"/>
    <dbReference type="InParanoid" id="A0A1C7NEU4"/>
    <dbReference type="OrthoDB" id="2279385at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="15"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="163"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="225"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="25"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="176"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="225"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="244"/>
            <end position="257"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ87597.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="340" mass="39652" checksum="D67EDD8D40763973" modified="2016-11-30" version="1">MMHGYRQQEPYWYNPQRSYSAHNHPTYRKRRSSRQRKPSKYKVIYEEDVFPDHPQVYPYDTSQPYRGPDQVSWLDPVSPYMMQSTGPPWPPHLNQPVITFDPMMMHFYPPQHLDTRATELLYPAHVLYDQAQRLPMMQPYFMPTGLPPNLASHFLDPMPFMDVASSKVDEPPSPDSQEKLEEVRPKSMAPSTSPIEPPQPLRRRLSLMESLLDSFSLLNEPKVMSQTSYQEMDPSTSESSGSNDEVKEEPKLIDRRPSLSRKLSKKANALQSRQFIWCYRLRDTEGALWTAFDVKNQSTLDKQYALLVSKKQQQQQNSDGSLNDEDITYGVSEYWHCLVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NEU9</accession>
    <name>A0A1C7NEU9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Trafficking protein particle complex subunit 6B</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">TRAPPC6B</name>
        <name evidence="2" type="ORF">A0J61_06088</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the TRAPP small subunits family. BET3 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000351">
        <property type="protein sequence ID" value="OBZ85854.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NEU9"/>
    <dbReference type="FunCoup" id="A0A1C7NEU9">
        <property type="interactions" value="22"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NEU9"/>
    <dbReference type="InParanoid" id="A0A1C7NEU9"/>
    <dbReference type="OrthoDB" id="941624at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005801">
        <property type="term" value="C:cis-Golgi network"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005802">
        <property type="term" value="C:trans-Golgi network"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030008">
        <property type="term" value="C:TRAPP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006888">
        <property type="term" value="P:endoplasmic reticulum to Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd14944">
        <property type="entry name" value="TRAPPC6A_Trs33"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1380.20:FF:000008">
        <property type="entry name" value="trafficking protein particle complex subunit 6B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1380.20">
        <property type="entry name" value="Trafficking protein particle complex subunit 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024096">
        <property type="entry name" value="NO_sig/Golgi_transp_ligand-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007194">
        <property type="entry name" value="TRAPP_component"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037992">
        <property type="entry name" value="TRAPPC6/Trs33"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12817:SF0">
        <property type="entry name" value="GEO08327P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12817">
        <property type="entry name" value="TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 6B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04051">
        <property type="entry name" value="TRAPP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111126">
        <property type="entry name" value="Ligand-binding domain in the NO signalling and Golgi transport"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006218"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ85854.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="173" mass="19597" checksum="62E0D2876CD41245" modified="2016-11-30" version="1">MSDDDSLSTRLVSETCMDLFLIEMVDTICRTTVAETDGDSDAVFYKLETLGYAVGQRLVERFTKDRPRFVDTLDVVKFICKDLWTIMFKKQIDNLKTNHRGVYVLQDNGFRWFMRMSTDVGGADSAKKAMPYVWFPCGIIRGALASLGVPTVVVAETSNLPQCTFQIKIVKQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NFA3</accession>
    <name>A0A1C7NFA3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">RRM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_04505</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000222">
        <property type="protein sequence ID" value="OBZ87439.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NFA3"/>
    <dbReference type="InParanoid" id="A0A1C7NFA3"/>
    <dbReference type="OrthoDB" id="2441396at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RRM" evidence="1">
        <location>
            <begin position="33"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ87439.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="114" mass="13377" checksum="62BF6CBF30D42C80" modified="2016-11-30" version="1">MTSALQAIKRTSLSPTRAFFRIPQKISSVDQAREIFKVLRSYGDMVEYKLMRCPETLDYLKYGFVVYKYRESANKAIQDQFIRVQSDLFSLPFDIKIELSQNNTYVTKQNKSET</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NFB5</accession>
    <name>A0A1C7NFB5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">GTPase-activating protein GYP5</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">GYP5_0</name>
        <name evidence="5" type="ORF">A0J61_04210</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000200">
        <property type="protein sequence ID" value="OBZ87748.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NFB5"/>
    <dbReference type="STRING" id="101091.A0A1C7NFB5"/>
    <dbReference type="InParanoid" id="A0A1C7NFB5"/>
    <dbReference type="OrthoDB" id="421393at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031267">
        <property type="term" value="F:small GTPase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.270:FF:000001">
        <property type="entry name" value="TBC1 domain family member 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.270">
        <property type="entry name" value="putative rabgap domain of human tbc1 domain family member 14 like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.750">
        <property type="entry name" value="Ypt/Rab-GAP domain of gyp1p, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.80">
        <property type="entry name" value="Ypt/Rab-GAP domain of gyp1p, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000195">
        <property type="entry name" value="Rab-GAP-TBC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035969">
        <property type="entry name" value="Rab-GAP_TBC_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050302">
        <property type="entry name" value="Rab_GAP_TBC_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47219:SF9">
        <property type="entry name" value="GTPASE ACTIVATING PROTEIN AND CENTROSOME-ASSOCIATED, ISOFORM B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47219">
        <property type="entry name" value="RAB GTPASE-ACTIVATING PROTEIN 1-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23436">
        <property type="entry name" value="RabGap-TBC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00164">
        <property type="entry name" value="TBC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47923">
        <property type="entry name" value="Ypt/Rab-GAP domain of gyp1p"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50086">
        <property type="entry name" value="TBC_RABGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0343">GTPase activation</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rab-GAP TBC" evidence="4">
        <location>
            <begin position="294"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="64"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="171"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="574"/>
            <end position="647"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="66"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="139"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="171"/>
            <end position="186"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022468"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OBZ87748.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="682" mass="78769" checksum="B673553D558EEEA2" modified="2016-11-30" version="1">MTTLYDTPINHQKDLYESGSDYEENDESLEMAEYDLDVVDDALLNPNSHEYMDHFGFKIHVRTDDESSSGDESDFEQVKKKTMPAVPSTTSTATSDDDSIDTTLTTPHQVYAQRSLDQKSPVVPILKNPPARQRSATYDSRESKETHRSSTSQNSARYSILSSFMKPATRPSSVVSVQSISRPSESYQRRQSKRYSDKPQVIGTPRSPGANHRHFDKLVSRFRRFSHNDHKYDSEKHVMLKEQAMEELGHYRDKGGYQNNSYDWDFWAMVIDDFGRVIETQMDDLRQNLSKNGGIPSPIRGLVWQLISKSRDSFDMELEYRDILKRSNSPFEKQIQRDISRTFPNHPYFMQESGRQSLFNVAKAYSVFDQEVGYCQGLAFIIGCLLLHMSEENAFCVLIKLMGKYGLRGHFTPRMEILHQHIYQFDNVFQQKLPVIHRHMENEGVTPSMYASQWFITLFAYRCPIEFAFRVIDLLLIEGTQVLIQIGLAIIVRNQEKILKLHFETLVDFLCNGVFTVFGDDGNSFVEDTYRVDLPARFMARLAQQFTGDEARESKSSSQEDNLRRVNGQLTEHIRAVEGQLQIVKTENKELTQKIIHAKMDHARTEDEKDQLKNDLARVKASFEKELQALRLENQRLADENTHLTGQLTDTESQLIHLKMSLAEQQGEFEALRHDLKKQHAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NFD1</accession>
    <name>A0A1C7NFD1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Ribose-5-phosphate isomerase</fullName>
            <ecNumber evidence="4">5.3.1.6</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">D-ribose-5-phosphate ketol-isomerase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">Phosphoriboisomerase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">RKI1</name>
        <name evidence="9" type="ORF">A0J61_04139</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>aldehydo-D-ribose 5-phosphate = D-ribulose 5-phosphate</text>
            <dbReference type="Rhea" id="RHEA:14657"/>
            <dbReference type="ChEBI" id="CHEBI:58121"/>
            <dbReference type="ChEBI" id="CHEBI:58273"/>
            <dbReference type="EC" id="5.3.1.6"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Carbohydrate degradation; pentose phosphate pathway; D-ribose 5-phosphate from D-ribulose 5-phosphate (non-oxidative stage): step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the ribose 5-phosphate isomerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.3.1.6" evidence="4"/>
    <dbReference type="EMBL" id="LUGH01000195">
        <property type="protein sequence ID" value="OBZ87812.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NFD1"/>
    <dbReference type="FunCoup" id="A0A1C7NFD1">
        <property type="interactions" value="677"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NFD1"/>
    <dbReference type="InParanoid" id="A0A1C7NFD1"/>
    <dbReference type="OrthoDB" id="1555531at2759"/>
    <dbReference type="UniPathway" id="UPA00115">
        <property type="reaction ID" value="UER00412"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004751">
        <property type="term" value="F:ribose-5-phosphate isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006014">
        <property type="term" value="P:D-ribose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009052">
        <property type="term" value="P:pentose-phosphate shunt, non-oxidative branch"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008615">
        <property type="term" value="P:pyridoxine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd01398">
        <property type="entry name" value="RPI_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1360:FF:000014">
        <property type="entry name" value="Ribose 5-phosphate isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.260:FF:000018">
        <property type="entry name" value="Ribose-5-phosphate isomerase A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.260">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1360">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00170">
        <property type="entry name" value="Rib_5P_isom_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037171">
        <property type="entry name" value="NagB/RpiA_transferase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020672">
        <property type="entry name" value="Ribose5P_isomerase_typA_subgr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004788">
        <property type="entry name" value="Ribose5P_isomerase_type_A"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF001924">
        <property type="entry name" value="PRK00702.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00021">
        <property type="entry name" value="rpiA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11934">
        <property type="entry name" value="RIBOSE-5-PHOSPHATE ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11934:SF0">
        <property type="entry name" value="RIBOSE-5-PHOSPHATE ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06026">
        <property type="entry name" value="Rib_5-P_isom_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75445">
        <property type="entry name" value="D-ribose-5-phosphate isomerase (RpiA), lid domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100950">
        <property type="entry name" value="NagB/RpiA/CoA transferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9" id="KW-0413">Isomerase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001713"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004988"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008088"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011959"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00019150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00029734"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00032273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OBZ87812.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="238" mass="26363" checksum="993B118EDAC28989" modified="2016-11-30" version="1">MSNPVEEGKKLAAYRAVDEYITPDLKVVGIGSGSTVVYVVERILQRPELKRIVYIPTSFQSKILILENGLQLGSIEQHPEIDVTIDGADEVDEELNAIKGGGACQFQEKVVAEAAKKFVIVADFRKKSQKLGTGWTKGVPIEVVPMTYKSVMKHIETKLSVKPVESKLRMAINKAGPVVTDNGNFVIDVHFGVIENPYELLKELKLLTGVYEVGLFCNMADKAYFGEENGSVDIWFKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NFZ0</accession>
    <name>A0A1C7NFZ0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glucose-induced degradation protein 4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">Gid4_1</name>
        <name evidence="2" type="ORF">A0J61_04022</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the GID4/VID24 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000187">
        <property type="protein sequence ID" value="OBZ87938.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NFZ0"/>
    <dbReference type="FunCoup" id="A0A1C7NFZ0">
        <property type="interactions" value="288"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NFZ0"/>
    <dbReference type="InParanoid" id="A0A1C7NFZ0"/>
    <dbReference type="OrthoDB" id="62at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034657">
        <property type="term" value="C:GID complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005773">
        <property type="term" value="C:vacuole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045721">
        <property type="term" value="P:negative regulation of gluconeogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043161">
        <property type="term" value="P:proteasome-mediated ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007039">
        <property type="term" value="P:protein catabolic process in the vacuole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006623">
        <property type="term" value="P:protein targeting to vacuole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018618">
        <property type="entry name" value="GID4/10-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14534:SF3">
        <property type="entry name" value="GID COMPLEX SUBUNIT 4 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14534">
        <property type="entry name" value="VACUOLAR IMPORT AND DEGRADATION PROTEIN 24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09783">
        <property type="entry name" value="Vac_ImportDeg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00061469"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ87938.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="280" mass="32316" checksum="89E21F916FA6CC22" modified="2016-11-30" version="1">MPIPSNHNLADSTCSNENNVMETETKISNHKQQSKTVTSLQDTCSDAMETDVAKEEDLPSKYKAHRKNQKRSLLLHARAEGEKIVDISETRLRPVSSNGLYAGSFFHGTQKCGIASYEVNVELLHVDLKESTLCGYLKIKGLTSEFPELTTFFEAEIIGSKYSFHTRKWQADQQSDLLHWKKFPSFAPYINTFNDDGFALDKTKADSDFVYMRWKELFLVPNHHVSAIHGASFAGFYYICYQRSTNRIKGFYFFRHHKDWFQELTLDHVPDHGMSAYEFR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NG27</accession>
    <name>A0A1C7NG27_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Serine/threonine-protein kinase ppk6</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">ppk6_2</name>
        <name evidence="5" type="ORF">A0J61_03965</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000183">
        <property type="protein sequence ID" value="OBZ87995.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="FunCoup" id="A0A1C7NG27">
        <property type="interactions" value="144"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NG27"/>
    <dbReference type="InParanoid" id="A0A1C7NG27"/>
    <dbReference type="OrthoDB" id="10252171at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035556">
        <property type="term" value="P:intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045719">
        <property type="term" value="P:negative regulation of glycogen biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000320">
        <property type="entry name" value="Serine/threonine protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.20">
        <property type="entry name" value="PAS domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24346">
        <property type="entry name" value="MAP/MICROTUBULE AFFINITY-REGULATING KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24346:SF51">
        <property type="entry name" value="PAS DOMAIN-CONTAINING SERINE_THREONINE-PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="4">
        <location>
            <begin position="434"/>
            <end position="691"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="469"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OBZ87995.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="697" mass="80618" checksum="9CAE582C6379F9DB" modified="2016-11-30" version="1">MRRHVTSPRRLSQPNLERFIDLDLTARSSLDVELQPAVTEKYSKALHAPTRFLPQNQAVLTTKQDGTILLFNDIASLCFKIDKSLIGQSVFXTLLEDPFRKQITTILNRRKQQPGHVLVCGTIVSIVKLNGTKSIASLWLKEKHSDQGDSIYLWIFEEIYETSLSVYMDSECIIHSVMGTMIDVYGYQESEMIGKPIYSLIPALAKEQRNRLDKMDELKFFGSQTSKGASFPVLLHLSRHVAMDQNDHANYVVKITSLPSITGSLILEPNTGRITDLSAVLAKYLFGRSMQHILDQPVYASDLIPCLSTLLPIMKRYNTLSSKQCRHFHNSDLIYVVHRDGSQFEMDLQLTNREDGLVEAIITYDRIRAFSRHERRLEHANKPKRPVAMRSLRISSFGSVEEHKRIFPTVDAFPHSPSPSHLDIANQSHSLDDYVILNALGQGTYGMAKLAYRKDDPSKKKVVIKYIFKSRILIDSWIRDRQLGSVPMEIHILRKLQRHPHVNCCQLVTFMEDEDYYFLVMDLLDNSMDLFDYIERNKNMTENETKRIFYQVACATKHLHQHGIVHRDIKDENIILDDQGRALLIDFGCATYYKRDKRFDTFTGTLEYCAPEMLRGQPYAGPPQDIWSCGVLLYTLIYQENPFHNIDEIMEKELRVPFVLSEESFDLITHMLQRDVESRFDIDDVLNHPWFHDIRQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-06-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NGB4</accession>
    <name>A0A1C7NGB4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_03808</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000172">
        <property type="protein sequence ID" value="OBZ88142.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NGB4"/>
    <dbReference type="InParanoid" id="A0A1C7NGB4"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ88142.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="111" mass="12750" checksum="A149B1EE8A6AFE39" modified="2016-11-30" version="1">MLTFLQLNCGQSNSLNSLRKHQDLLTYKQPDTVLSSSDKKNAGSFNNTIANHVLDYTRSQRMWWVPALGMKIGGRFPYPEVLEKILMMTPFLEQTQGLKAYNHILCLRFAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NGG2</accession>
    <name>A0A1C7NGG2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Vacuolar protein sorting-associated protein 35</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">VPS35_0</name>
        <name evidence="7" type="ORF">A0J61_03755</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Plays a role in vesicular protein sorting.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the VPS35 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000168">
        <property type="protein sequence ID" value="OBZ88203.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NGG2"/>
    <dbReference type="FunCoup" id="A0A1C7NGG2">
        <property type="interactions" value="945"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NGG2"/>
    <dbReference type="InParanoid" id="A0A1C7NGG2"/>
    <dbReference type="OrthoDB" id="10258141at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005770">
        <property type="term" value="C:late endosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030906">
        <property type="term" value="C:retromer, cargo-selective complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042147">
        <property type="term" value="P:retrograde transport, endosome to Golgi"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.660">
        <property type="entry name" value="Vacuolar protein sorting-associated protein 35, helical subcomplex Vps35-C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005378">
        <property type="entry name" value="Vps35"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042491">
        <property type="entry name" value="Vps35_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11099:SF0">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11099">
        <property type="entry name" value="VACUOLAR SORTING PROTEIN 35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03635">
        <property type="entry name" value="Vps35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF009375">
        <property type="entry name" value="Retromer_Vps35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006536"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRNR" id="PIRNR009375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OBZ88203.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="798" mass="92114" checksum="A460AD2C929D1104" modified="2016-11-30" version="1">MTFSLPPPPSTKEHLKEALDVVKIQSKLMRHCLDKHRLMDAIKACSSLLSELRTDELSPRHYYELYMTVFDTMRHLTSYLVETHTSGKHHLGDLYNLVQYASSIVPRLYLMVTVGTVYLSVPDAPPHADVLLDMIEMTKGVQHPIRGLFLRHYLGGMTRDFMPQKQIEDIEAIIQFYLTNFAEMNKLWVRMQHIGHSRDREKRESERKELATLVGTNLVRLSQLEGVDLKLYETTVLPGIMNEVVSCQDVLAQEYLMDVVIQIFPDEFHMHTLKPFLATTAQLQAQVQIKTIIMSLLDRLSSFAQQEVMDYGELFVLFWQEIVELVKTRRTALPMQDQTSLFLSLAQFSVSCYPNRLDYMDRIYLFAYEEYHLNQSSDYQIHSKQSDTNLLELLLLPVKTWDVLLVITTLKHYQSLLVIQPYMTRRRVALAILESILSQSRQIDQPEQVYQLLEICHVLINTSTVTPLRNSLEEASLQERDSNGWVARLVHLFYSPDNDLQFLLLSAARQQLEQAVDDGCKIRAVLPSLIISSLQLARRYAQDTTQTEYHKKMTALYTFLHQLIMLLNQHSTGQDSICVQFALMAGQNADFCKDFDDIAFQFYLDAFRIYQESVAHSRAQFNAIVYAIGTLLTTSDLFRQHHLLELSHQLTQFGTKLLKKPDQSRAVFLSSHLWEPHGRVTDCLDKSIKIADHCIDLATNQMLLIELLNQSLYYFEKQSNSEITADVLNTLIATISTHMQHLKASDQPLTTSSSNLMETENLKDYVSCQWKQTVRHIQACRARSEHYLAIQCPDISLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NGP6</accession>
    <name>A0A1C7NGP6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="10">NFX1-type zinc finger-containing protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">Znfx1_1</name>
        <name evidence="10" type="ORF">A0J61_03625</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000159">
        <property type="protein sequence ID" value="OBZ88331.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NGP6"/>
    <dbReference type="InParanoid" id="A0A1C7NGP6"/>
    <dbReference type="OrthoDB" id="2423195at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031380">
        <property type="term" value="C:nuclear RNA-directed RNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002376">
        <property type="term" value="P:immune system process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031048">
        <property type="term" value="P:regulatory ncRNA-mediated heterochromatin formation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06008">
        <property type="entry name" value="NF-X1-zinc-finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045055">
        <property type="entry name" value="DNA2/NAM7-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041679">
        <property type="entry name" value="DNA2/NAM7-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041677">
        <property type="entry name" value="DNA2/NAM7_AAA_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046439">
        <property type="entry name" value="ZF_RZ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000967">
        <property type="entry name" value="Znf_NFX1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10887">
        <property type="entry name" value="DNA2/NAM7 HELICASE FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10887:SF341">
        <property type="entry name" value="NFX1-TYPE ZINC FINGER-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13086">
        <property type="entry name" value="AAA_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13087">
        <property type="entry name" value="AAA_12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20173">
        <property type="entry name" value="ZnF_RZ-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00438">
        <property type="entry name" value="ZnF_NFX"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51981">
        <property type="entry name" value="ZF_RZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0391">Immunity</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <keyword evidence="5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RZ-type" evidence="9">
        <location>
            <begin position="1897"/>
            <end position="1978"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="23"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1972"/>
            <end position="1991"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="58"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="103"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="138"/>
            <end position="157"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022859"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51981"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OBZ88331.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="1991" mass="224289" checksum="2E8513154881B6D0" modified="2016-11-30" version="1">MSKSFAQFKEVVKSRSTIYDLDNQKRKVETPSQRSGIVTMDHLVPPRPKITRKKPTTASPNETYVDQTRQRVLTSDSTIKANGNEKPNSIQSNSSQTYSHYTPNEKSHASTKESDNNHRSETQSVSGTISADPAWAAESTSFNHTSSKQKTQQSPNHRQPRSREQTIDSIQFTKRMPGAGSFEDIKSEAINSWGEGVDLELESGARAKKRADWLAPGDFFASTTDSSNSSESHIKNDISVPASMHPTDEQQSYASAAKQKTPAWAIENSTMSFDTHTASFTQTTEWRTNNQLHHISPQVPHMAPLVVMPSGYPYLPITNGFAANPNSSNPAAVTAALMVPSLPDGIAHPNSMMLHDERDMESGLYLISFLENHDQKSTLIEFQKKVGHLLHHRLPEFSMRNFSLLVDVLAIAMEHEIHHKAHVETARKIKEVWGLFKARLIHYTQAYAYMPTELEGLLQFSMALSYHEPKLAPELPVSDYLSMYQRMSKSIASDTRENILKYLYKLKTISASDKSVDNLWDDAPSQDLPLIPNASLVITEVSEQVNLLKGYQDQHGTIITNQTNPAWSDNISDYFVTQFLLLREEMIGPAKKVMNNLFRESSDQHYSEYQHASPKALTLLASSSEPAVVFQLGHVHTTDNPMLDFQEGYLVFLLPERDLTSKSQRRPSIKSVADKALMGQAIRASMRHNALGQPLRIVSIHINKNDLPKLNWSKRYTLITSPINAASTLSTLEWLYESCYNLDIKKFSFVLTPRLIAATNILSPEQMKAWEERYANSAIESNADAIPDYIGDAEIDVSCIMTRTNTSHRACPGTDSWPSHPPQVRDISSKLPSLYCLSPSQLKSVKFALTHRIAIISGAPGTGKTFLASKLAQLLSNALTAGQFHQPVLVIAKSQSSLDDILSNVVSAIPNIVRFGGELHKDNLIEKQITRQATLSVSDPNYRQHQHLERQLARNQAHLNGLLNLRAQISDHDPSILSTSIPPSHRQMLEKGFVKTYGASSYISDIAIWSSWASHDKKSKTFDSVAKPRHSFFKSLQWQMESAYVKRAGRGLLPLMDQHLVKNRFANVANMSFPILPITSATRWPFESSENQSGPHIRTALMNEWKKVPADCIWTISEEEKTKLIEGLVSVMISFIDKEIQHVMQEQVKAAQAHDDNLIQKWLSLCRFNRIIGMTADFASAHREFLANLWPRSVIVDEASEILESTVSSIVLGPRTEHVILLGTSDCLKKPRINNDALAGEPHQLDISLFERWKLTNIEKAHLEEQWRMHSEIARVVSQFNARKKNGANSLLITAPLASRDENLVDGKRPAKEVLYGITQRALYVHYKPHEYTQRDDHFAHAYYSRMLMTEVTNAQVDEARFVASFGTYLSQQPYPSPDIAILTISNLQKSLITAILKEEIPKRTCFVSNIKNIAVETVDQYLGRQNSFTILSTATPGHYRNTIDNVSHALTRAKYGLFVVGQPDVDQVHPQWKEFAKYMQECGLYSHSIRLTCHTHGDTINAKHWKDFLMMKNGGCQNPCGTLMNDGHVCKEECHFLSHSEVICREPCNRLRPTGCAHACRRKCYECSKEGICPPCTEETEVVLPCGHKQVNLCHRLQGNQNNRQQVKCHEIVKVELPCGHTKQIECYQAHQKNVDKLKCDVKQSVTLACGHTAMSHCGVETICAEPCKESLECGHKCKELCGMLHSHSRSECAASCPKQLICGHMCAKGCANPDQHTERCIEKCNYTCSHGYKCSRECYKDCIRCISECPYRCAHYKCTKKCFEICDRPPCEAPCRIKLSCGHKCSGLCGENCPPCMICEKQLKCSITLRHLYEFEKDEKIYQLPECGCVFAVEALDAYFETQAKNGEHTAIKLWQCPECQKPIYTALRYSKYIKIEIALVNAIKIRMEKDRQKLTHHEREQIINAMNDETRHHRVYNIVGGRWFVCENQHPYYVGDCGGATEISKCPECDAPIGGTKHRVVESNRFYGEFDGSEKPAWPAQPGASSEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NH54</accession>
    <name>A0A1C7NH54_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Pathogenesis-related protein 5</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_03528</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000153">
        <property type="protein sequence ID" value="OBZ88427.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NH54"/>
    <dbReference type="STRING" id="101091.A0A1C7NH54"/>
    <dbReference type="InParanoid" id="A0A1C7NH54"/>
    <dbReference type="OrthoDB" id="430315at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.110.10">
        <property type="entry name" value="Thaumatin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037176">
        <property type="entry name" value="Osmotin/thaumatin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001938">
        <property type="entry name" value="Thaumatin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31048">
        <property type="entry name" value="OS03G0233200 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00314">
        <property type="entry name" value="Thaumatin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002703">
        <property type="entry name" value="Thaumatin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00347">
        <property type="entry name" value="THAUMATIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00205">
        <property type="entry name" value="THN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49870">
        <property type="entry name" value="Osmotin, thaumatin-like protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51367">
        <property type="entry name" value="THAUMATIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="disulfide bond" evidence="1">
        <location>
            <begin position="19"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="1">
        <location>
            <begin position="73"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="1">
        <location>
            <begin position="78"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="1">
        <location>
            <begin position="84"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="1">
        <location>
            <begin position="104"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="1">
        <location>
            <begin position="114"/>
            <end position="124"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR002703-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ88427.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="164" mass="17225" checksum="0296B73639058B49" modified="2016-11-30" version="1">MPTTKRVQVLLPVVPSKDCDGSADCHPGAPASLAEFLFKGAQGKDFYDVSFVDGYNLPITISPDSGNADGYECGVPACAALPDCPKELQDKDANGNVVGCKSACAAFGTDEYCCTGDAAQRGECVASKYSSPVKDACPDVYTYAYDDNTSMFSCSSHGYTVTFC</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NI29</accession>
    <name>A0A1C7NI29_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">GmrSD restriction endonucleases N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_03247</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000136">
        <property type="protein sequence ID" value="OBZ88705.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NI29"/>
    <dbReference type="STRING" id="101091.A0A1C7NI29"/>
    <dbReference type="InParanoid" id="A0A1C7NI29"/>
    <dbReference type="OrthoDB" id="5419821at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004919">
        <property type="entry name" value="GmrSD_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036086">
        <property type="entry name" value="ParB/Sulfiredoxin_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39639">
        <property type="entry name" value="CHROMOSOME 16, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39639:SF1">
        <property type="entry name" value="DUF262 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03235">
        <property type="entry name" value="GmrSD_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110849">
        <property type="entry name" value="ParB/Sulfiredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GmrSD restriction endonucleases N-terminal" evidence="2">
        <location>
            <begin position="20"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="407"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="421"/>
            <end position="433"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ88705.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="433" mass="50335" checksum="2B8361BAF6790AFA" modified="2016-11-30" version="1">MVHRQLPTPKTRMLTTWKLKDMIRKKELIMDAPYQRAIVWETNKMSELVDSILNNYYIPPLLFATRKIRGKQTRIVIDGKQRLTSMRRFMRNLIPYVDTSTGESVSTYYADQSDNERDDEEEANIRKSKPSPIHFLDEAMFDKFSSYEFVCVEYTDISEDDEYEIFSRVQLGVAITSAERLKAHNTPVAKLCRQLASEHNLLTEVLQRKKSADVFQIISHLLMTLRDDPKDFKGTIRALLEFVSSSFNPPTTLTNTLRHVLSVYHAILSDEDHAVALYKRGRSPCAMKALEFLAFGKYISLVKRHRSPSLFARDFISFREFLFDKREGKFYLGREAFNDAMIWVDRQISQENLAPLVQSAHQYSTISSDEEEEEGVDRDQLKDDEYEHEPTYTNPYHSSTLAVANKRRRDERINGTVPVARRGRRMAGGIPRH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NJ17</accession>
    <name>A0A1C7NJ17_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Autophagy-related protein 2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">ATG2</name>
        <name evidence="14" type="ORF">A0J61_04642</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>a 1,2-diacyl-sn-glycero-3-phospho-L-serine(in) = a 1,2-diacyl-sn-glycero-3-phospho-L-serine(out)</text>
            <dbReference type="Rhea" id="RHEA:38663"/>
            <dbReference type="ChEBI" id="CHEBI:57262"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>a 1,2-diacyl-sn-glycero-3-phosphoethanolamine(in) = a 1,2-diacyl-sn-glycero-3-phosphoethanolamine(out)</text>
            <dbReference type="Rhea" id="RHEA:38895"/>
            <dbReference type="ChEBI" id="CHEBI:64612"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Preautophagosomal structure membrane</location>
            <topology evidence="2">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the ATG2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000231">
        <property type="protein sequence ID" value="OBZ87314.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="FunCoup" id="A0A1C7NJ17">
        <property type="interactions" value="176"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NJ17"/>
    <dbReference type="InParanoid" id="A0A1C7NJ17"/>
    <dbReference type="OrthoDB" id="18982at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061908">
        <property type="term" value="C:phagophore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034045">
        <property type="term" value="C:phagophore assembly site membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032266">
        <property type="term" value="F:phosphatidylinositol-3-phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043495">
        <property type="term" value="F:protein-membrane adaptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000045">
        <property type="term" value="P:autophagosome assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000422">
        <property type="term" value="P:autophagy of mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061723">
        <property type="term" value="P:glycophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006869">
        <property type="term" value="P:lipid transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034727">
        <property type="term" value="P:piecemeal microautophagy of the nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061709">
        <property type="term" value="P:reticulophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026849">
        <property type="entry name" value="ATG2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13190">
        <property type="entry name" value="AUTOPHAGY-RELATED 2, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13190:SF1">
        <property type="entry name" value="AUTOPHAGY-RELATED 2, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13329">
        <property type="entry name" value="ATG2_CAD"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0072">Autophagy</keyword>
    <keyword evidence="12" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="8" id="KW-0445">Lipid transport</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="751"/>
            <end position="798"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1349"/>
            <end position="1371"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="12">
        <location>
            <begin position="1584"/>
            <end position="1614"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="754"/>
            <end position="773"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="774"/>
            <end position="786"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="1349"/>
            <end position="1358"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004406"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004623"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00018070"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00024479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00024615"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="OBZ87314.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="1887" mass="215190" checksum="2E9126F032B672F7" modified="2016-11-30" version="1">MKAWTYLTGLTSYVLPNNIQKRLYKFVLRRLIGQFLEKELDLENFDIALASGNMELRDLSVNKEFINKMLADTPFLLEEGKIGCITACIPWSKLLSADILLEIQGLDLTMKPIKNKPKPKEPTFFGSKSIIEEHIMSSSLHFADDFLRTEIDQTQELHRSMQESYGATASEDSIDLDTEGLQVLSKVVDKMISRIKIDIVNTVLRIIHSSAVPLTSNQPLEQSDYHIEVRIPRISYFDQTPEYNERMMESSVLLPNEPSAYIKEDETIKVITVTSPEVWLKSAAQFNTSSSSSSSSCSSQDTSPLAQSIYVPSSSSLFRYEGDSDSLSQTEFFETDQANSSIFQSQYSANMMSGSITPKANPSNQAPPYEALLLTTMDKLSHIVLRLRPLMDTISPMSVKQVELKLAHVRTMMTPHQLAFFMDFMDTLSTSHTDDLDALSHQPSLSPTLSTEALLDDLDAMQRPSSNPIPSTPLLDQKIKFKLPLFEFFMLADEESTLDCKTTPKGNHLCLAIEQLRGRFQRTQHNTSVIDVRVLDIKLNEWIKRPAFVRHQSTSQTRYHHYNPILQFDNRIKQDYSDQDQFPEYENRPSSPLSYHQTLLDSPEALRIRVEMRQAREPGRFVDAVSFEQDVNVELAAFKLHVDPRTIDRLDSYLYAVLDYQKHKTTPYIHSRPSTTRQEEKIFDDLQVIENIQKRKIRVRCAFIRLLLSVPDMSAVSTREEFNDLFHQSQLSVDIKKLMGTWSSTTVVDESHHTTPNATHATTHPTVHTPTGTLASSSPGVSTLNPDSRHPKRPHKPNKIHIDLNYINVFLQPSPEEKVKCWFTSKTVLNSKKSLSEDGLSPSIEITIQDKDAIYPGTSVRSGYFGAGSEIPKNLFDFLERNESFNGEQKLHIPMEDQSDSAMIFKQRTIETSLFVVNCHFPQADMDLPKKLWDTVQIVQNDLILWQPRFLLHQSKLNPPTPQSRVDDPKKPSLFSIVAVMSHGTWDLHTSPLHTFRLQFSDFRYFAAIQHLGQNENITTLDIEELDLWDLSNKQQLLHKTMPKEIHPKRNTSMVSLFSRLTQYPELNQIDKVTSVVACHLCWKATTQLDFIQQLIAFQKMPDDMVFIDPPTQYIKVYAHLLETSVDYSPVHSPSCAVLVLDGVQVMTNILAGQPLIEIKNCIQSIELYLVDDRQSLDIQGVHQQLASKFSDTRKYWATLGLVNILTIQNIELAVKLRLDDHLAAPQLDVALVSTDITIDSSADSFQTLINLLTYLQNDGDQSQCVSLSPKTKPVASTFVEQESRPIPFNHHRRRRSSTIKVYRENMLASLDEEAFKLSPPKISPPTLIEAPEMEDCYVEEFYQTNEPSSSFYSTTRLPPTKPRRKQHRSKTSEDIIRVLLSDQSEEKAHLRFEMVEDFFGVEKRVQPPTHAVDTTKAVLCLRVSHLNLVWRLYDGYEWDYVQLEMATKEVQPQSGFGDHQKRQRGREAHIEFRLDQVSIDLDWMPAHDSTAMHLDLSIKDVEIIDHIKTSNWKKFLGYMRSGSQQREVDECMVNIELTSLRPVLNDPQQEFRLKIKLLPVRLYVDQDPLDFLEKYFSFDKTCLRSTEAANQSIETKKQQQEETEQQQQESNDLFFQHVDIHPIVLKVDYKPKHFKLGNVKEGQYLELVKLFHLDGAEISLTHVKLTGIQGIQGLFDRLGQEWLPHLKQTSQVFNVASGVPPVRSLVNLGTGVADLVLLPIQQYKKDGRLMKGIQRGTSSFARATAIEAIKLSSKMATGTQVILEHADGFFSTSQPNQKAVSDHQQYHFIYTEGVDLQDDELQIIGKEELDPTEYNNLGSATQTIFAVPTDIQDEDTSKTVVRAVPIAVIKPMIGLTGALQSILAGLRNSIDPTMRLQSEDKYKKRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NK00</accession>
    <name>A0A1C7NK00_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">SWIM-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">A0J61_02630</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000101">
        <property type="protein sequence ID" value="OBZ89320.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NK00"/>
    <dbReference type="STRING" id="101091.A0A1C7NK00"/>
    <dbReference type="InParanoid" id="A0A1C7NK00"/>
    <dbReference type="OrthoDB" id="2213870at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007527">
        <property type="entry name" value="Znf_SWIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039903">
        <property type="entry name" value="Zswim2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21540:SF0">
        <property type="entry name" value="PHD FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21540">
        <property type="entry name" value="RING FINGER AND SWIM DOMAIN-CONTAINING PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50966">
        <property type="entry name" value="ZF_SWIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="SWIM-type" evidence="3">
        <location>
            <begin position="106"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="40"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="42"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00325"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OBZ89320.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="167" mass="18788" checksum="041B6120486D538B" modified="2016-11-30" version="1">MSSVSSNDSYGYSDSSFSTDTEQQIGYMLDQFVKEEHFVTPTLPSTTTDDNTISTPPPQPASKIPDQLESRLKRVSKEPIRILSSKMTNYENGHEFKVRGSTGKTYIVTIGPKLDCTCYDHKIRSVHCKHILYVLLKELKVQDLTSTIYITQFPSSDSVLGPYHMAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NKC5</accession>
    <name>A0A1C7NKC5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Tubulin beta chain</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="primary">Tubb3_0</name>
        <name evidence="16" type="ORF">A0J61_02374</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11 12">Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="4 12">Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
            <location evidence="2">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 12">Belongs to the tubulin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000088">
        <property type="protein sequence ID" value="OBZ89577.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NKC5"/>
    <dbReference type="FunCoup" id="A0A1C7NKC5">
        <property type="interactions" value="144"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NKC5"/>
    <dbReference type="InParanoid" id="A0A1C7NKC5"/>
    <dbReference type="OrthoDB" id="1662883at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005200">
        <property type="term" value="F:structural constituent of cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000070">
        <property type="term" value="P:mitotic sister chromatid segregation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007052">
        <property type="term" value="P:mitotic spindle organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097435">
        <property type="term" value="P:supramolecular fiber organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd02187">
        <property type="entry name" value="beta_tubulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.600:FF:000002">
        <property type="entry name" value="Tubulin beta chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1330.20:FF:000002">
        <property type="entry name" value="Tubulin beta chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1440:FF:000006">
        <property type="entry name" value="Tubulin beta chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.600">
        <property type="entry name" value="Helix hairpin bin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.20">
        <property type="entry name" value="Tubulin/FtsZ, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1440">
        <property type="entry name" value="Tubulin/FtsZ, GTPase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013838">
        <property type="entry name" value="Beta-tubulin_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002453">
        <property type="entry name" value="Beta_tubulin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008280">
        <property type="entry name" value="Tub_FtsZ_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000217">
        <property type="entry name" value="Tubulin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037103">
        <property type="entry name" value="Tubulin/FtsZ-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018316">
        <property type="entry name" value="Tubulin/FtsZ_2-layer-sand-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036525">
        <property type="entry name" value="Tubulin/FtsZ_GTPase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023123">
        <property type="entry name" value="Tubulin_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017975">
        <property type="entry name" value="Tubulin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003008">
        <property type="entry name" value="Tubulin_FtsZ_GTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11588">
        <property type="entry name" value="TUBULIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00091">
        <property type="entry name" value="Tubulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03953">
        <property type="entry name" value="Tubulin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01163">
        <property type="entry name" value="BETATUBULIN"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01161">
        <property type="entry name" value="TUBULIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00864">
        <property type="entry name" value="Tubulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00865">
        <property type="entry name" value="Tubulin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55307">
        <property type="entry name" value="Tubulin C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52490">
        <property type="entry name" value="Tubulin nucleotide-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00227">
        <property type="entry name" value="TUBULIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00228">
        <property type="entry name" value="TUBULIN_B_AUTOREG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="10" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="9 12" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 12" id="KW-0493">Microtubule</keyword>
    <keyword evidence="7 12" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tubulin/FtsZ GTPase" evidence="14">
        <location>
            <begin position="47"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="domain" description="Tubulin/FtsZ 2-layer sandwich" evidence="15">
        <location>
            <begin position="246"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="421"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="13">
        <location>
            <begin position="429"/>
            <end position="454"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00034296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU000352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="SMART" id="SM00864"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="SMART" id="SM00865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="OBZ89577.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="454" mass="51197" checksum="0FB1363E69638B22" modified="2016-11-30" version="1">MREIIHLQAGQCGNQIGQKFWETISQEHGIDENGNYKGDDDLQLERINVFYNEGSKDKYVPRAVLVDLEPATMDAIRSSQYGKIFRPDNFVNAQSGAGNSWAKGYYTEGAELVETIMDVVRKEAENTDCLQGFQLCHSLGGGTGSGLGSLLLSKIREEYPDRILSTYSVVPSPKVSDTVVEPYNAVLSVHQLVENCDATFCIDNEALYDICFRTLKLTNPGYGDLNQLVSGVMSGVSTSLRFPGQLNSDLRKLCVNMVPFPRLHFFMVGIAPLTASNSQQYRNLSVPELTAQMFDARNMMAASDPRHGRYLTAATIFRGRLSTKEVENQMLAVQQKNSSYFVEWIPNSVKTSLCDIPPVGLKMSGTFIGNSTAIQDLFKRVNEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQEATVDDEYDEEEYDDEHMEEEDEEAMEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NKG7</accession>
    <name>A0A1C7NKG7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">WD repeat-containing protein 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">Wdr3</name>
        <name evidence="6" type="ORF">A0J61_02385</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the WD repeat WDR3/UTP12 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000089">
        <property type="protein sequence ID" value="OBZ89555.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NKG7"/>
    <dbReference type="FunCoup" id="A0A1C7NKG7">
        <property type="interactions" value="1069"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NKG7"/>
    <dbReference type="InParanoid" id="A0A1C7NKG7"/>
    <dbReference type="OrthoDB" id="407922at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034388">
        <property type="term" value="C:Pwp2p-containing subcomplex of 90S preribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032040">
        <property type="term" value="C:small-subunit processome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034511">
        <property type="term" value="F:U3 snoRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000480">
        <property type="term" value="P:endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000447">
        <property type="term" value="P:endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000472">
        <property type="term" value="P:endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.10:FF:000172">
        <property type="entry name" value="WD repeat domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.10:FF:000178">
        <property type="entry name" value="WD repeat domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007148">
        <property type="entry name" value="SSU_processome_Utp12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051570">
        <property type="entry name" value="TBC1_cilium_biogenesis"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19853">
        <property type="entry name" value="WD REPEAT CONTAINING PROTEIN 3 WDR3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19853:SF0">
        <property type="entry name" value="WD REPEAT-CONTAINING PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25173">
        <property type="entry name" value="Beta-prop_WDR3_1st"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25172">
        <property type="entry name" value="Beta-prop_WDR3_2nd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04003">
        <property type="entry name" value="Utp12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="12"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="7"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 4" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="57"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="99"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="198"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="415"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="496"/>
            <end position="530"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="591"/>
            <end position="632"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="633"/>
            <end position="665"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="675"/>
            <end position="707"/>
        </location>
    </feature>
    <feature type="domain" description="Small-subunit processome Utp12" evidence="5">
        <location>
            <begin position="808"/>
            <end position="911"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00038229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF04003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OBZ89555.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="945" mass="106770" checksum="8D52EDA2170D1C04" modified="2016-11-30" version="1">MVKAYLRYEPLATFGVIASTLANVLYDQTGKIAIAPALEEVVLWDLKKGTQVGKWREFGNKSEVTCIAKSPNNKDFAVGYGDGTIRLWNIQSSTSTVTLSGHRAAVTALAFDSDGTRLASGSKDTDLIIWDIVSESGLYRLKGHKDQITCLTFLDPKKNSELDDSEVGISSEGYVLSSSKDTLIKLWDLSAQYCRETLVGHRSEVWSFAVSQDQKVIISGGAENQLKAWKIDWKILGLSLEALGQQEQQKKKEEDAMQVDSPQPATLQKAINSYGQILRQSRDRIVTIHFHPSGKFVGVQANDRSVEVLRVRDHEQIRKKIQRRKKRAREKGKDEAEISEEIEAHDEFTFECLVRTPAKVRSFDFAPIVDVEKTGELQLVVSLSNNTVEAYSVPVSHEKKTEESQEPSRLYSIDGPGHRSDIRSLALSGDDELLASASSNLLKVWNMKTRACIRSIECGFAICSAFLPGNKHILIGTKTGELELYDIGSSSLVESVKAHDGPVYSMQVRPDKRGFVTGSADKDVKFWDFDMVQDKNSAAKRLTFVHMRTLKMSDEVLCVRYSPDQNLLAVSLLDSTVKVFYHDTLKFFLSLYGHKLPVLSMDISSDNTLIATCSADKNVKLWGLDFGDCHKSLFAHQDSVMAVQFVWGTHYFFTVSKDKTVKYWDGDKFENIMKLEGHHGEVWALAIAKHGSYVITGSHDRSLRIWEKTDEQLFLEEEREKELEELYENTLVSQLEKTDVNGNEMEIDSAGKQTMETLKAGERLIEAIDIGDEEKNGWLAYENAKSKGLPGQPPQRHAILMAMGDIEPDRYVLDVLKKIKANDLEEALMILPFSKVMSLFSYIESWAKKNWSIVLVSRVLFSLVKTHHNQIVANRMMRPMLDSIRHHLRTQLQRQKDIMGYNRAALAYIQRDYKARNTTDFLDETIENKSAADDEKKRKFVKLSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-06-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NKM1</accession>
    <name>A0A1C7NKM1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_02262</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000083">
        <property type="protein sequence ID" value="OBZ89671.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NKM1"/>
    <dbReference type="InParanoid" id="A0A1C7NKM1"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ89671.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="75" mass="8408" checksum="E3C15C3888347F16" modified="2016-11-30" version="1">MVSEAMLNTLLYMKQSFSSIVYSQTKHVLGEIITIETTVGGESQFDSVKTYRNAEGSTHILLCGTCNLKTKLFWI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NLS6</accession>
    <name>A0A1C7NLS6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_01896</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000066">
        <property type="protein sequence ID" value="OBZ90052.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NLS6"/>
    <dbReference type="InParanoid" id="A0A1C7NLS6"/>
    <dbReference type="OrthoDB" id="2212603at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12937">
        <property type="entry name" value="F-box-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00256">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="1">
        <location>
            <begin position="1"/>
            <end position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ90052.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="573" mass="65574" checksum="ED488DACE87D6711" modified="2016-11-30" version="1">MTDWYSLPLELWNMIFELLPKSDLVQCQLACDGWCSVVNKIMYTEIILSTVTQKTTLINTLLQSSYAPGSYLKRFYLNNTPITTTQASWDIQAVVHQLAVHCPFLESISVAQPSDVLYQQIVRELGMNRLQHLNKLSYPETYGEALESYTRAIVLLRKRITVIKLSDYVTPSFYKKAYVPLMENVADFVCVETVLFEKRKECTPILLDDLIDALPSLKEIKFVLHQPLPLGNYKYACRTLPRPNMRRFSINRIAGSDTAFMYIMTKFPNLEHLVMDGASPSQPSLSSYPASVSRHEVAAYLSQLKSFRISGLENMLSLALLLNQNVLPGNLQIKLCFDMSPETVQGSLDLDYQQDVNSKKKYVHLFVCKMSRSVQLVPLLKQFGSLAHEFTLWHAGEELGDEDDLDLVLEHCPNLRHMHLKNYQIDTCQSTNSSLCTLALVKCFYSSQALNTLSQRLPSLYRLDIVKSSRISSHRDMIASHIYCSMPETNFKLLQYKWSCLRKLSDDMYLQLSTSSHPQRHYKINTTSIYPVTSQEYNQHVTNEQVLTINLVCSELQCLNVTEGQLSICHTFI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NM51</accession>
    <name>A0A1C7NM51_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">A0J61_02442</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000092">
        <property type="protein sequence ID" value="OBZ89516.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NM51"/>
    <dbReference type="STRING" id="101091.A0A1C7NM51"/>
    <dbReference type="InParanoid" id="A0A1C7NM51"/>
    <dbReference type="OrthoDB" id="2262349at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050797">
        <property type="entry name" value="Carb_Metab_Trans_Reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31668">
        <property type="entry name" value="GLUCOSE TRANSPORT TRANSCRIPTION REGULATOR RGT1-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="4">
        <location>
            <begin position="31"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="66"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="567"/>
            <end position="635"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="577"/>
            <end position="598"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OBZ89516.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="734" mass="83954" checksum="8B73C60AFD2723BB" modified="2016-11-30" version="1">MSQERKKKAIEYHFVDMNDPDRYKKLKVARACDFCRKRKSKCDVGVPGSSTCSNCKKSNRICQFSPVTQQQTTHHETDSKQKSSKNQTPPVLTNTLTQTFQFYSQHSPLHSPHTDTTPQRLSFTTNYINQNPFFSIDHQGYCGYEKHGSILNTHLLLGSVLHELPTYTKQFEQELFDVYFCYVHPCYPILDRYSISQTLRYDNNAIPLSLKWAVMAIALRFTKQYPDANLISIAYHQHACIELDGKEPSLFTLQTLFLLYKYQELLTPVGMPMTAAALTYLRHIQAMIPEVQQQLNENSSTWPLQDEMLCRASWILLIIVSMSSPADSRFSELMDYCTTPTRKPVLTETEHYDKTELQTACNLIQLINLTLLFSRGICLLSNHASLFVYGDDPKFNLLASDLEEWKAALPPSISAEFVNQQQHPFYDASSHPASTFMAYICLIHDILQLILAIQQPSAHHAEYVVSKAFQLSYRAYQFCVHDMHLSKLAFIQGSRLIAYGLTIAYQSLYYCYAEQQEQHRQTFLECRSLIFQTFESLHLIPQLFMALQTLNNQLDAKEKLLSAEKHHYQPPPLSNASTSDSFSTPPTGSSGTLTTDTSQSRSGDYFFGSNPPSFYESSSSTSTPGYHQRTTHLEQRSWPENAYPSEENSFHDNLIHHYETNAPMTPTFEDDTGMSSIDLHYGPLTPPVPHLMVDSYFHTVVEHTRRDGSSIAMANDLLPMEIKNFKSCERKRLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NM85</accession>
    <name>A0A1C7NM85_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_02384</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000089">
        <property type="protein sequence ID" value="OBZ89556.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NM85"/>
    <dbReference type="InParanoid" id="A0A1C7NM85"/>
    <dbReference type="OrthoDB" id="2097874at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ89556.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="138" mass="16090" checksum="F12E653EF96482DB" modified="2016-11-30" version="1">MQTDLEAVQDMIQKETKPCSPNKSLTKEFAEKLHKDYQQMSPDDTWHLNDILRNRMIMFGPSVDKIKVAQNLCLWLPQLQPQKWWNKIPILVLSPKTEKPSKEASSGMIVFSSDMTMEDLKHHLEKNIDQILKDANKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NMD8</accession>
    <name>A0A1C7NMD8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Transmembrane protein 62</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">Tmem62_0</name>
        <name evidence="7" type="ORF">A0J61_03516</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000153">
        <property type="protein sequence ID" value="OBZ88434.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NMD8"/>
    <dbReference type="STRING" id="101091.A0A1C7NMD8"/>
    <dbReference type="InParanoid" id="A0A1C7NMD8"/>
    <dbReference type="OrthoDB" id="45365at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056229">
        <property type="entry name" value="Ig_TMM62"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056230">
        <property type="entry name" value="TMEM62_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14795">
        <property type="entry name" value="HELICASE RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14795:SF0">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 62"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24384">
        <property type="entry name" value="Ig_TMM62"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24394">
        <property type="entry name" value="TMEM62_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="Metallo-dependent phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008889787" evidence="3">
        <location>
            <begin position="22"/>
            <end position="825"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="491"/>
            <end position="509"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="569"/>
            <end position="587"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="625"/>
            <end position="645"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="666"/>
            <end position="685"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="705"/>
            <end position="727"/>
        </location>
    </feature>
    <feature type="domain" description="Calcineurin-like phosphoesterase" evidence="4">
        <location>
            <begin position="72"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="domain" description="TMEM62 Ig-like" evidence="5">
        <location>
            <begin position="357"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="domain" description="TMEM62 C-terminal" evidence="6">
        <location>
            <begin position="496"/>
            <end position="653"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="779"/>
            <end position="825"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="816"/>
            <end position="825"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF24384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF24394"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OBZ88434.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="825" mass="94327" checksum="3EFAF25275C6B38B" modified="2016-11-30" version="1">MKLSSSSFICLSITLIGLLRSIQLYLSSTQDLRVANEQDPWFFRQPKTDVEHSLTGKESTPIGNQPEKIFYFVQVSDLHISKFQPKGHTIHFLHFLQSVLPNLKPEFVVITGDLIDAKDATKTVSAQYREEWQVYRAAIDQSANGTVWYDMRGNHDCFDLTSWQAENNYYRDFGESSQLLNEGKGVYSWQISKPFGDYNFVAVDACPKKGPSRPFNFFGYLTTNTMNRLVSSILSKTYNHTFMFGHYPTTTLVPGVSSEGYTFRDLASRFSIYFCGHLHRLTAGLGDVLKSYNRGTDSLELELSDMKDHGSYRIVAVDHDLISFVDVDLPITDIPPATQLIPLKSNGKIIWPRKLKTAPTVLITNPKDSRYTLPTKEPLASSHHSSHIRFLVFSEYEHSLLKVRLFVDDKHHPFPAEFVGHSSKTTNLPLWTSVWEPNDFNDFATHTLRVEVTAPNGQIGTHQISFRMDNMRVKIQGGAGEWIVWSDIASLLRFLSIFALGAMLITLIVPKVFNDYEQYSGHAHTLRDQLLLCIHEIDAGLNLSIYANVQRHIYTWTHRFLQFPEAQPNVWYLCFGLLLSLLTLPWFKTELIPSGREQAQNMGYFYLWALMLEPGNQWIPLADTWMYAIFEVTFTVAVFILYFVWKSTDAYQFHCKGNPEGGSIEYQNVCDRIWFQVLVLIYWLWRFKGLTELAVWYGSAWPTLVFNVLVWWLLAVLVVLIMGKHGIMSYVNSHRRHQVGAQPVSAPLAICSACCNAVGDLSQHQSDTNLQEFEISNSQLTDESPLTVSTSEEEESRRLIYDESGSDSSSTEARRAFRRSTLKKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NML9</accession>
    <name>A0A1C7NML9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Proteoglycan 4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">Prg4</name>
        <name evidence="2" type="ORF">A0J61_03437</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000148">
        <property type="protein sequence ID" value="OBZ88514.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NML9"/>
    <dbReference type="STRING" id="101091.A0A1C7NML9"/>
    <dbReference type="InParanoid" id="A0A1C7NML9"/>
    <dbReference type="OrthoDB" id="2289669at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016187">
        <property type="entry name" value="CTDL_fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02389">
        <property type="entry name" value="Cornifin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56436">
        <property type="entry name" value="C-type lectin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008889789" evidence="1">
        <location>
            <begin position="20"/>
            <end position="411"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ88514.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="411" mass="41857" checksum="6FD5095EFA5AC34A" modified="2016-11-30" version="1">MKSIIFASVALVAAASAQGFPNTNAQMPRSCQNGLYFIPPRFVSQDRAAQVCNAFGGRLVDVSNNNFLQLTTLASTCLGPQSRAWIRTWDGNNYNSNCLAIYTGVGYPGGAINLDCVGQNFNPPVCMRTGGIPPIVYPNPIPTIVAPTTTSTIAPTTRVVTSTRVVTSTSVVASSTTTTTTPATPNAAQASLLGLAADLSDVAAGVSSSASEASLIASNLSLFAIDFTDVPASTVTVTVTPTVTPVVPPPQSSLASLASELSDVASGISASAAEASLIASSLSEAASGITAPVPTTVTVVPEPTAVVVPEPTTIVVPEPTTVVVPEPTTVVVPEPTTVVVPEPTTVVVPEPTIVVPEPAIVVVPEPTIDTIVEPALPTVTALPVEPATDLIITETLPSNSDVTLTVVETII</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NMY7</accession>
    <name>A0A1C7NMY7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Holocytochrome c-type synthase</fullName>
            <ecNumber evidence="10">4.4.1.17</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">Hccs</name>
        <name evidence="12" type="ORF">A0J61_03319</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Lyase that catalyzes the covalent linking of the heme group to the cytochrome C apoprotein to produce the mature functional cytochrome.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>holo-[cytochrome c] = apo-[cytochrome c] + heme b</text>
            <dbReference type="Rhea" id="RHEA:22648"/>
            <dbReference type="Rhea" id="RHEA-COMP:10725"/>
            <dbReference type="Rhea" id="RHEA-COMP:10726"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
            <dbReference type="ChEBI" id="CHEBI:83739"/>
            <dbReference type="EC" id="4.4.1.17"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 10">Mitochondrion inner membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the cytochrome c-type heme lyase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.4.1.17" evidence="10"/>
    <dbReference type="EMBL" id="LUGH01000140">
        <property type="protein sequence ID" value="OBZ88634.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NMY7"/>
    <dbReference type="FunCoup" id="A0A1C7NMY7">
        <property type="interactions" value="334"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NMY7"/>
    <dbReference type="InParanoid" id="A0A1C7NMY7"/>
    <dbReference type="OrthoDB" id="4243at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005758">
        <property type="term" value="C:mitochondrial intermembrane space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004408">
        <property type="term" value="F:holocytochrome-c synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000511">
        <property type="entry name" value="Holocyt_c/c1_synthase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12743">
        <property type="entry name" value="CYTOCHROME C1 HEME LYASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12743:SF0">
        <property type="entry name" value="HOLOCYTOCHROME C-TYPE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01265">
        <property type="entry name" value="Cyto_heme_lyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00821">
        <property type="entry name" value="CYTO_HEME_LYASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00822">
        <property type="entry name" value="CYTO_HEME_LYASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 10" id="KW-0349">Heme</keyword>
    <keyword evidence="6 10" id="KW-0408">Iron</keyword>
    <keyword evidence="9 10 12" id="KW-0456">Lyase</keyword>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 10" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5 10" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="53"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="11"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="86"/>
            <end position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU363130"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="OBZ88634.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="273" mass="31618" checksum="A119E74A4977BDB4" modified="2016-11-30" version="1">MQPTTTSSDKCPIDHTQLKKEEPKCPVDHTQLKNPTESAAQCPVDHTSYKHFLPPTTPDAKESCPVDPSSYKHFMPPKEGCDSDAIDSSNNMPKVSQQQRQPDQKLPLSLDREISTIPRSNSDDKLWIYPSEQMFFNAMRRKNWSPEEKDMSVVVPIHNAVNEMAWQKILEWENMHQTECNQPKLEKFEGRPKDITPKARIRSWFGYSLPFDRHDWVVDRCGQKVTYVIDFYSGKQDPNKPMSLSFYLDVRPAVSPAGIWDRLKMSFRKGQFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NNS1</accession>
    <name>A0A1C7NNS1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">A0J61_01327</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000040">
        <property type="protein sequence ID" value="OBZ90630.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NNS1"/>
    <dbReference type="InParanoid" id="A0A1C7NNS1"/>
    <dbReference type="OrthoDB" id="5595797at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000446">
        <property type="entry name" value="Zinc finger protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021386">
        <property type="entry name" value="SPP41_DUF3020"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11223">
        <property type="entry name" value="DUF3020"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="6">
        <location>
            <begin position="9"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="53"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="59"/>
            <end position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OBZ90630.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="171" mass="20646" checksum="EF862FDF34FE8815" modified="2016-11-30" version="1">MAEESDNQYICTKCSKLFATRSNLKRHMENPNIHNMPYERSRDQKRWQGHARKISSRAETTERMRKWRAQNKEKNKQNDLRCRVYRIARQKFGKKESEEKNRFIEEEINKRTRRITIPTEQDNHHHTNYLNELPFYCAPLDKIELPSIRTSKQPIVKTEVPINLPPMQPKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NPF9</accession>
    <name>A0A1C7NPF9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_00931</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000025">
        <property type="protein sequence ID" value="OBZ91002.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NPF9"/>
    <dbReference type="InParanoid" id="A0A1C7NPF9"/>
    <dbReference type="OrthoDB" id="2220517at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="31"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ91002.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="237" mass="27393" checksum="535C85B88DBC8578" modified="2016-11-30" version="1">MSLIQINGYSIRFVLDEKYVELAPKDLIEDIYGVALIWMLIPGSLILLLLAPLLMNTTIHEEFETPLTEYYSLCGYHIASKEKMPYQKYHQESFQFFSQLPSLKTSDINQFARASIARYLNHELISDYYGKDCWLSKSKFQVYVKKQKATYEISNRLFHGSKKYDKDNIVGSKQKNDFKWVSSPPENHDAKSRMPIIAYGNATFSSSMRGEVVAPTKRITQAIRKLANTMAKLNLFM</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NQ03</accession>
    <name>A0A1C7NQ03_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="10">CDP-diacylglycerol--inositol 3-phosphatidyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">pis1_0</name>
        <name evidence="9" type="synonym">pis1_1</name>
        <name evidence="10" type="ORF">A0J61_00990</name>
        <name evidence="9" type="ORF">A0J61_11342</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001928">
        <property type="protein sequence ID" value="OBZ80609.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="LUGH01000026">
        <property type="protein sequence ID" value="OBZ90979.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="FunCoup" id="A0A1C7NQ03">
        <property type="interactions" value="617"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NQ03"/>
    <dbReference type="InParanoid" id="A0A1C7NQ03"/>
    <dbReference type="OrthoDB" id="10251079at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003881">
        <property type="term" value="F:CDP-diacylglycerol-inositol 3-phosphatidyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006661">
        <property type="term" value="P:phosphatidylinositol biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1760">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043130">
        <property type="entry name" value="CDP-OH_PTrfase_TM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15362:SF4">
        <property type="entry name" value="CDP-DIACYLGLYCEROL--INOSITOL 3-PHOSPHATIDYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15362">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1208">Phospholipid metabolism</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 10" id="KW-0808">Transferase</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="57"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="122"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="189"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="217"/>
            <end position="235"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OBZ80609.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OBZ90979.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="264" mass="30534" checksum="02E3471E616B19B1" modified="2016-11-30" version="1">MSPISIDKEHVAKVKKMIEVIKVTMDKNYAFKSNRKTNYSTDKPQRIPVIRELSWRLCLYTICLGILKSVLLCIVYLVYWMLLMEMLLDILINVSSKFGAVLDMVTDRCTTTCLLCFLSLQYPQWTILFQLLISLDFXSHYMHMYRLTRDLFSFWGGGENSSMISGSSSHKKISEKQSWYLRIYYTNNIVLFIMCAGNELFFVALYVLKFIGSLNMFWYIALSVTGIICFAKQFINIVQIVNASKTLANIDQEDKAKESSGKNN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NQ21</accession>
    <name>A0A1C7NQ21_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="16">Pre-mRNA-splicing factor cef-1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="16" type="primary">cef-1</name>
        <name evidence="16" type="ORF">A0J61_00766</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CEF1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000019">
        <property type="protein sequence ID" value="OBZ91197.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NQ21"/>
    <dbReference type="FunCoup" id="A0A1C7NQ21">
        <property type="interactions" value="805"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NQ21"/>
    <dbReference type="InParanoid" id="A0A1C7NQ21"/>
    <dbReference type="OrthoDB" id="1410009at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000974">
        <property type="term" value="C:Prp19 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005681">
        <property type="term" value="C:spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd00167">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd11659">
        <property type="entry name" value="SANT_CDC5_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.60:FF:000021">
        <property type="entry name" value="CDC5 cell division cycle 5-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.60:FF:000091">
        <property type="entry name" value="CDC5 cell division cycle 5-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047242">
        <property type="entry name" value="CDC5L/Cef1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021786">
        <property type="entry name" value="Cdc5p/Cef1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017930">
        <property type="entry name" value="Myb_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001005">
        <property type="entry name" value="SANT/Myb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047240">
        <property type="entry name" value="SANT_CDC5L_II"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45885">
        <property type="entry name" value="CELL DIVISION CYCLE 5-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45885:SF1">
        <property type="entry name" value="CELL DIVISION CYCLE 5-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11831">
        <property type="entry name" value="Myb_Cef"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13921">
        <property type="entry name" value="Myb_DNA-bind_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00717">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51294">
        <property type="entry name" value="HTH_MYB"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50090">
        <property type="entry name" value="MYB_LIKE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="6 12" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0227">DNA damage</keyword>
    <keyword evidence="9" id="KW-0234">DNA repair</keyword>
    <keyword evidence="7" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="8" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0747">Spliceosome</keyword>
    <feature type="domain" description="HTH myb-type" evidence="15">
        <location>
            <begin position="2"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="domain" description="Myb-like" evidence="14">
        <location>
            <begin position="6"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="domain" description="Myb-like" evidence="14">
        <location>
            <begin position="54"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="domain" description="HTH myb-type" evidence="15">
        <location>
            <begin position="58"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="110"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="264"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="418"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="12">
        <location>
            <begin position="753"/>
            <end position="787"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="132"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="264"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="423"/>
            <end position="444"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010506"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="OBZ91197.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="787" mass="89207" checksum="60FFBE5973EE7BAC" modified="2016-11-30" version="1">MKFIIKGGVWKNTEDEILKAAVSKYGKNQWARISSLLVRKTPKQCKARWYEWLDPSIKKTEWSKEEDEKLLHLAKLMPTQWRTIAPIVGRTPAQCLERYQRLLDEAESKDSERAAELGLTGSVGHEAGPSADDVRKLRPGEVDPEPESKPARPDPVDMDEDEKEMLSEARARLANTQGKKAKRKARERQLEEARRLTALQKRRELKAAGIHMRLRQKKGVMDYNTDIPFEKKPSLGFYDTTEEANKKVDPGKLTNVHLSKLNRRRADIEDEKNREKKRKAKANPNAHLEGNQGRFVPAKNAKIVQMQEQEQIAKRRKLVLPAPQVGEQELEEIVKSGFAGENTKNLVLDSEVDATQGLVGDYAFTPNTMATRTPRAPPSNDNLMVEARNLIALSNAQTPLLGGENTKLHEGTGFEGVTPKTAPIQTPNPLATPLRQNTNTTAFGNETPFKTPREAKAFQTQRKRTLLESLSSLPKPRNEWEIKLPEMKQEKEQTASSGLPASVDSVDDMTDLEHEMKVSAESEAKERAARRSMAVQLNLPRPTILPDLKLDPSSSEAEQLIHEELVRLLNHDAAKYPVVGGKVAPGATQLADSLAQLEEEFDSKTLQEARQEMDKEIAQQFGFELTDIKQAVWQHVSEHPSFEKKWQQEHDELLFSAKFNQFMTLEEMDDEKDIIQGLDKIVEANRQTMIRDATRAGKLENKLDVRLGGYMNRSKVLSQQIIQAFEEFEAANIEYQSFVSLQIAEKAAIPRRVEALEDEVYKLASRERDLQQKYKELTEEKMALLAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NQF1</accession>
    <name>A0A1C7NQF1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Protein ras-2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">ras-2_1</name>
        <name evidence="5" type="ORF">A0J61_00610</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the small GTPase superfamily. Ras family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000014">
        <property type="protein sequence ID" value="OBZ91355.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NQF1"/>
    <dbReference type="STRING" id="101091.A0A1C7NQF1"/>
    <dbReference type="InParanoid" id="A0A1C7NQF1"/>
    <dbReference type="OrthoDB" id="5976022at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000654">
        <property type="entry name" value="Small g-protein ras2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001806">
        <property type="entry name" value="Small_GTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020849">
        <property type="entry name" value="Small_GTPase_Ras-type"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24070">
        <property type="entry name" value="RAS, DI-RAS, AND RHEB FAMILY MEMBERS OF SMALL GTPASE SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00071">
        <property type="entry name" value="Ras"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00449">
        <property type="entry name" value="RASTRNSFRMNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00175">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00173">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00174">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51419">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51421">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51420">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="163"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="170"/>
            <end position="183"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008344"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OBZ91355.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="183" mass="20721" checksum="5500B1D8A43CB3BE" modified="2016-11-30" version="1">MMLYKLVVLGDGGVGKTALTIQTYDPTIEDSYRKQVVIDDQPCVLEVLDTAGQEEYTALRDQWIRDGEGFLLVYSIASRSTFERIERFRNQIFRVKDLENVPMMLVGNKCDKVTEREVTREEGAAMAKQLACDFIETSAKTCVNVERSFYQVVKAIRAQREGLKPGGPKGKSKKEKKSKCLIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NQI1</accession>
    <name>A0A1C7NQI1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">UBA domain-containing protein 7</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">ucp7_1</name>
        <name evidence="5" type="ORF">A0J61_00579</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000013">
        <property type="protein sequence ID" value="OBZ91363.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NQI1"/>
    <dbReference type="FunCoup" id="A0A1C7NQI1">
        <property type="interactions" value="74"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NQI1"/>
    <dbReference type="InParanoid" id="A0A1C7NQI1"/>
    <dbReference type="OrthoDB" id="1717591at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0101031">
        <property type="term" value="C:protein folding chaperone complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd14291">
        <property type="entry name" value="UBA1_NUB1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.110:FF:000002">
        <property type="entry name" value="putative tyrosine-protein phosphatase auxilin isoform X2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.10">
        <property type="entry name" value="DNA helicase RuvA subunit, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051966">
        <property type="entry name" value="RPAP3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015940">
        <property type="entry name" value="UBA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009060">
        <property type="entry name" value="UBA-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46423">
        <property type="entry name" value="RNA POLYMERASE II-ASSOCIATED PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46423:SF1">
        <property type="entry name" value="RNA POLYMERASE II-ASSOCIATED PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13181">
        <property type="entry name" value="TPR_8"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22562">
        <property type="entry name" value="UBA_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00165">
        <property type="entry name" value="UBA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46934">
        <property type="entry name" value="UBA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50030">
        <property type="entry name" value="UBA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0802">TPR repeat</keyword>
    <feature type="domain" description="UBA" evidence="4">
        <location>
            <begin position="232"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="2">
        <location>
            <begin position="489"/>
            <end position="522"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="2">
        <location>
            <begin position="580"/>
            <end position="613"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="54"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="182"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="278"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="347"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="401"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="630"/>
            <end position="676"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="8"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="67"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="85"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="207"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="278"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="350"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="401"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="439"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="630"/>
            <end position="651"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50030"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OBZ91363.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="797" mass="88870" checksum="D6E914051DB0F3B8" modified="2016-11-30" version="1">MDDLLDLNWSSNTNATSTPPPSSSSIKLDSKPKDAFADLLSTPAKPVDVTKLSMLEQQRLRQQQQQPSWASPQRSTTPLSQHTMTPSPKSSAAPSPSLSATTNTKSSLDDLLGSFGTPKKQNQPDKHMPLNQLRAQMHNVPMTHQSESDWDFDFLSSKSNTTNTSVSKDNLDPFDMDSLTQSTSVSVTEIEQEDDNPLGVLAEPASVSASFSQTESTPPSPPLQNKDEISDEQEDEMVARLIDMGFSMRQSKFALEATGGHDLQAAIDLLVQHTEEQQQQQQQQQQPRPQQQQQQQQQRQQQPQRQESDMHIQSEKLMSQAQELGGFLYKNATSYLKAGRQKVTKAVTDWQEQQRTQRLQESSGRPKWMTDQTQEPHMISKTVERFADDQDSDDELKEQTRALDLQKNELAKKRQEEQKKKEAMITEDTYVSPSRRRPASSGRSTPRSAPTPSSPPIPAKETTTASPKPVKISVSRPRVNASPTVMVQVNQARELGNQKFKLGQFGDAETAYSQAIKLLPSGHDHLVLLCNNRAMTRLKTGEYKQCIEDCDKAIAINRQNNDGGDIEVEGVTIVWRDQMTKSLYRKAEAYENLENYQEALTVYGQLVKLEGTQNLKVNRGMARCRQALNPKQPLKASSASALSSPSPQPKQDLMSVFDPSKQASSSPVSEEELKKSKAVTAMRAKAAEQEAEEAERLEKTDAVNTRLTAWKAGKEQNLRALLATLDTLLWPGAQWKGAQMSELINPKKCKICYMKAIGKVHPDKLPADVTVEQRMIASGIFAALNEAWDAFKAQNQM</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NQI7</accession>
    <name>A0A1C7NQI7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Transcription initiation factor IIE subunit beta</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">tfa2</name>
        <name evidence="10" type="ORF">A0J61_01259</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6 7">Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Tetramer of two alpha and two beta chains.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the TFIIE beta subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000038">
        <property type="protein sequence ID" value="OBZ90686.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NQI7"/>
    <dbReference type="FunCoup" id="A0A1C7NQI7">
        <property type="interactions" value="462"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NQI7"/>
    <dbReference type="InParanoid" id="A0A1C7NQI7"/>
    <dbReference type="OrthoDB" id="3907302at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005673">
        <property type="term" value="C:transcription factor TFIIE complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016251">
        <property type="term" value="F:RNA polymerase II general transcription initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001097">
        <property type="term" value="F:TFIIH-class transcription factor complex binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006367">
        <property type="term" value="P:transcription initiation at RNA polymerase II promoter"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054600">
        <property type="entry name" value="TFA2_E-tether"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040501">
        <property type="entry name" value="TFA2_Winged_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016656">
        <property type="entry name" value="TFIIE-bsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003166">
        <property type="entry name" value="TFIIE_bsu_DNA-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12716:SF8">
        <property type="entry name" value="TRANSCRIPTION INITIATION FACTOR IIE SUBUNIT BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12716">
        <property type="entry name" value="TRANSCRIPTION INITIATION FACTOR IIE, BETA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22254">
        <property type="entry name" value="TFA2_E-tether"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18121">
        <property type="entry name" value="TFA2_Winged_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02186">
        <property type="entry name" value="TFIIE_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016398">
        <property type="entry name" value="TFIIE-beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51351">
        <property type="entry name" value="TFIIE_BETA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="10" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="5 7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0804">Transcription</keyword>
    <keyword evidence="2 7" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="TFIIE beta" evidence="9">
        <location>
            <begin position="64"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="25"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="37"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00025581"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRNR" id="PIRNR016398"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51351"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OBZ90686.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="284" mass="32037" checksum="2F83F81469118FBE" modified="2016-11-30" version="1">MSSLNSQLQNFKKSFKASTDIAVKRAGQATVHKDSTKTTSGSISNNTKASFESESKKRKRATVYSQPANTGTGHHAMSQLYTVIQFLKDSDTPQSVTSIVSRTKVDITKNKLLWDKLAENEKIEYDPVNNTFAYKPTYQIRSKEDLLSLLIQHKDEGGMDYKDLKDSYSKLSSAVEELAASGQILVVRNKDGNPRVLFYNDIEYNTPIDSEFKQMWSEISIPDETDLPKALEAAGLKTMEVFEKKVTSESKPKRSKTRNKRIKITNTHLSHIDLSKDYVPANKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NR78</accession>
    <name>A0A1C7NR78_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">ATP-dependent RNA helicase DED1</fullName>
            <ecNumber evidence="1">3.6.4.13</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">ATP-dependent RNA helicase ded1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="16" type="primary">ded1_0</name>
        <name evidence="16" type="ORF">A0J61_00330</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">ATP-binding RNA helicase involved in translation initiation. Remodels RNA in response to ADP and ATP concentrations by facilitating disruption, but also formation of RNA duplexes.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.13"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="11">Belongs to the DEAD box helicase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.13" evidence="1"/>
    <dbReference type="EMBL" id="LUGH01000007">
        <property type="protein sequence ID" value="OBZ91613.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NR78"/>
    <dbReference type="STRING" id="101091.A0A1C7NR78"/>
    <dbReference type="InParanoid" id="A0A1C7NR78"/>
    <dbReference type="OrthoDB" id="196131at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd18787">
        <property type="entry name" value="SF2_C_DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000008">
        <property type="entry name" value="ATP-dependent RNA helicase RhlB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000397">
        <property type="entry name" value="Probable ATP-dependent RNA helicase DDX4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000629">
        <property type="entry name" value="RNA-helicase_DEAD-box_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014014">
        <property type="entry name" value="RNA_helicase_DEAD_Q_motif"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47958">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE DBP3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00039">
        <property type="entry name" value="DEAD_ATP_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51195">
        <property type="entry name" value="Q_MOTIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 11 16" id="KW-0347">Helicase</keyword>
    <keyword evidence="3 11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DEAD-box RNA helicase Q" evidence="15">
        <location>
            <begin position="307"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="13">
        <location>
            <begin position="338"/>
            <end position="531"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="14">
        <location>
            <begin position="542"/>
            <end position="704"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="15"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="234"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="702"/>
            <end position="729"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Q motif" evidence="10">
        <location>
            <begin position="307"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="20"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="12">
        <location>
            <begin position="54"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="80"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="160"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="244"/>
            <end position="259"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00024397"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00024405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00025161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00047984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU000492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="OBZ91613.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="729" mass="81935" checksum="F64A6CAAC3435689" modified="2016-11-30" version="1">MSHWQNKKLVETYNEHEWNKSAQQKTGWNTQSNESSGDSAFGNNGHDNQRTRPGGRGRGGYESGRGHGRGSHQQRDRSNDQPWNSRPANQGSWENQSSNTRNWDQPDNSAQKQESGSSDGWSTVTKTNQSRSETKPSSNNWNQTSWAAKMNEPKPDKQEPNQWNTAKSDNQWNTTKSNQWATESKPASGGWNASAQQDRWATKTKETPAATGWDAPSKTDKVDQWGTVTLDSLGWSDTGKRRKDAKEPGKGIWKDGQHELGEENEELRLKLFGTPTDDLTLHSGINFDKYDNIPVEVVGHDPSDFLTTFEDAQMDDHLRTNIELARYKVPTPVQKHSVPIVLKGNDLMACAQTGSGKTAGFLFPILSAMFSRGPKPDPKEPPIKQGYQTYRKAYPQALILAPTRELASQIYNEARKFCYRSYVRPCVAYGGADIQQQLRLLDRGCHLLVATPGRLVDILERRRISFKNIQYLVLDEADRMLDMGFEPQVRRIVENEDMPSSVDRQTLMFSATFPDKIQALARDFMKEYVFLSVGRVGATSENITQKILLVKDEEKRSCLLDVLENHKDQKGLTLVFTETKRMADAVCDFLNENHYAATAIHGDRVQSEREASLDLFRRGVMPIMVATAVAARGLDIPNVMHVISYDLPSDIDDYVHRIGRTGRAGNTGHATSFFTHSNRFVASDMVKLLKGAHQEVPGWLQSMADDPANAPSNASPMGGRRNNRRPRVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NRE1</accession>
    <name>A0A1C7NRE1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Rpb7-binding protein seb1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">seb1</name>
        <name evidence="5" type="ORF">A0J61_00362</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000007">
        <property type="protein sequence ID" value="OBZ91598.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NRE1"/>
    <dbReference type="FunCoup" id="A0A1C7NRE1">
        <property type="interactions" value="62"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NRE1"/>
    <dbReference type="InParanoid" id="A0A1C7NRE1"/>
    <dbReference type="OrthoDB" id="79367at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006569">
        <property type="entry name" value="CID_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008942">
        <property type="entry name" value="ENTH_VHS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048892">
        <property type="entry name" value="Nrd1_Seb1_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04818">
        <property type="entry name" value="CID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21380">
        <property type="entry name" value="Nrd1-Seb1_dom2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00582">
        <property type="entry name" value="RPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48464">
        <property type="entry name" value="ENTH/VHS domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51391">
        <property type="entry name" value="CID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="CID" evidence="4">
        <location>
            <begin position="6"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="3">
        <location>
            <begin position="411"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="187"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="227"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="544"/>
            <end position="605"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="227"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="255"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="286"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="328"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="367"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="386"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="544"/>
            <end position="553"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="562"/>
            <end position="579"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="580"/>
            <end position="590"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51391"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OBZ91598.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="605" mass="68451" checksum="6AE2A799D80EBC53" modified="2016-11-30" version="1">MTDTWDRTLFDKDLKAILETKLPVSASKITALQSLATAHPQHHNYIVQCITRFIENAPPDYRLAGLYVIDAISRVVHKQQRKREDSQDGRLSDLEGYLKRFSIVLRDDALKGCFEPCSAKDKEKVRKTLDFWEQGNLYSKDLVQYLKTSFLNSKQVEQHQKVTPPPVDTASLLATLSTIGNGSLANLTIPGLTPTPAPPQVQSPTNEQDKNALPPALAKLLGGLVSTPATASSTPASPTSSVSDPRVRNDPRMASVNNELTQPKNWPPPQGPSIPARASTERKSRWSNANDNTNPTLNQSAHDPWSQRQGIQDPRMPPQAPNYLPAYQQSNPVPSYQQPNPPQSYQQPNPTQPYQQSNPTQPYQQPLYHTQPTYHSPYQQPQEQRISSEDRGTEPTHDPSLPPGCIRVLTRTLFVGPIPDHYERDDVAQLFMRYGELASVIVSKKIKGRHNAFLKFTTRASTEAAKYNSVNLIVQDVPVKVNWAFGFGPKKHFNYDRGDSIIPLSELSTEEKENLVTAPLGGFQGQPVRERMVIEEPEAQYRPEWKNNDEPRGTKRFYRPGFQHEDNNKRGRFQHEDNRQNFYPQFQPSYQPYDPSSMIPYSNQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NS36</accession>
    <name>A0A1C7NS36_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Ketohexokinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">KHK_1</name>
        <name evidence="4" type="ORF">A0J61_00733</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000018">
        <property type="protein sequence ID" value="OBZ91206.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NS36"/>
    <dbReference type="STRING" id="101091.A0A1C7NS36"/>
    <dbReference type="InParanoid" id="A0A1C7NS36"/>
    <dbReference type="OrthoDB" id="204058at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1190.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002173">
        <property type="entry name" value="Carboh/pur_kinase_PfkB_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052562">
        <property type="entry name" value="Ketohexokinase-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011611">
        <property type="entry name" value="PfkB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029056">
        <property type="entry name" value="Ribokinase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42774:SF3">
        <property type="entry name" value="KETOHEXOKINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42774">
        <property type="entry name" value="PHOSPHOTRANSFERASE SYSTEM TRANSPORT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00294">
        <property type="entry name" value="PfkB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53613">
        <property type="entry name" value="Ribokinase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00584">
        <property type="entry name" value="PFKB_KINASES_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 4" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Carbohydrate kinase PfkB" evidence="3">
        <location>
            <begin position="5"/>
            <end position="301"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OBZ91206.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="309" mass="34792" checksum="4FA50D6D1EF33DCA" modified="2016-11-30" version="1">MKGHSILLVGQVYLDNILHVDHFPKEDTKLRAFAAEQRLGGNTCNTAQVLAQSQPSNVYYLSAVGSRETSSYIIESLKPVKTSDTFLYRQNQITPSSTIIHSKETSSRTIISNNNLDEISLEEFIKVFEQLHSDNGWWVHFEGRNIAETIRQIEWLKKKATQEGWDSKLIISIELEKPDRPDIDLLLPLGDIAFFSKLYAQHHGYQTPASFLSELEKKLCPNAIAFCTWGAESAVAFNNKTKQTWHALPPPVDEVIDSVGAGDTFIAGVIYHMTHFDASLEEVLEFACHLATKKVSQQGFQQLLVCEPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NSW6</accession>
    <name>A0A1C7NSW6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Mitochondrial group I intron splicing factor dmr1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">dmr1</name>
        <name evidence="3" type="ORF">A0J61_00164</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000003">
        <property type="protein sequence ID" value="OBZ91786.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NSW6"/>
    <dbReference type="STRING" id="101091.A0A1C7NSW6"/>
    <dbReference type="InParanoid" id="A0A1C7NSW6"/>
    <dbReference type="OrthoDB" id="5588846at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051222">
        <property type="entry name" value="PPR/CCM1_RNA-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002885">
        <property type="entry name" value="PPR_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00756">
        <property type="entry name" value="PPR"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47942:SF63">
        <property type="entry name" value="PENTATRICOPEPTIDE REPEAT-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47942">
        <property type="entry name" value="TETRATRICOPEPTIDE REPEAT (TPR)-LIKE SUPERFAMILY PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01535">
        <property type="entry name" value="PPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13041">
        <property type="entry name" value="PPR_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13812">
        <property type="entry name" value="PPR_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51375">
        <property type="entry name" value="PPR"/>
        <property type="match status" value="5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="PPR" evidence="2">
        <location>
            <begin position="173"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="repeat" description="PPR" evidence="2">
        <location>
            <begin position="208"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="repeat" description="PPR" evidence="2">
        <location>
            <begin position="243"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="repeat" description="PPR" evidence="2">
        <location>
            <begin position="278"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="repeat" description="PPR" evidence="2">
        <location>
            <begin position="313"/>
            <end position="344"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00708"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ91786.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="643" mass="74231" checksum="8453D19F56C5DBCA" modified="2016-11-30" version="1">MLSRTILSGRSRLATCTLPTRSRTLATKSGLQEDRTKKVVEEIKRLKYQLESKQKQTSGPFEKIDDQEIAAIYKELAAPTPVRPKISPDYLESLRLKFLDTRPLVEGNPTPALVDDSVTQPSDNALIEQQKNAIRDFTVEDFEQLIYANALAKRSSEAQQAFDLMQKYNLTPSVKAVNHLMDAYANTNQLEQVVSLFKRLDDMGLKADMYTYASLIKAFVGSKRLEDAFVLFEKMKEMSLIPSQPIFSSLISGCLKSNQFDRAWEVFDSMRLSYHQPDEVSFTLMLHACAKRGEVERALNLFEDMAGHHLYPTDVTFNVLINACAKRPDYYNEAFSLLDQMQSSYGFLPDRITFNTLLMACARKKDLVQARRILDFMWQDTTSLLSPDHHTYTNLFWCYASYQPTAKTKVESQPKETSSALSTEQHRLSMQAPTTRTQMIQEVHWLFKQMPQTVQRTSGLLNAYLAIHVSHKQPMATCLKIYNKLFTQYKLKHDAFTFSHMLDYCYKTKEHNLAWKVWEDYQDFLEERSRLGHASATLSEQKAIENEKHVLAIKEGWTDQQQQQLAVLMANTLGRCDDIENAMSLLISESRRIGLDSPRLRDMMPLYNKCVQLEDEQNRQQLIQLCSKDPYRAQSKKFKRVYT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7LQV2</accession>
    <name>A0A1C7LQV2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Homeodomain-like DNA binding domain-containing transcription factor</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_11940</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01002736">
        <property type="protein sequence ID" value="OBZ65154.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7LQV2"/>
    <dbReference type="STRING" id="101091.A0A1C7LQV2"/>
    <dbReference type="InParanoid" id="A0A1C7LQV2"/>
    <dbReference type="OrthoDB" id="2214365at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="30"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="44"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="237"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ65154.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="237" mass="27671" checksum="991472E2C991DA94" modified="2016-11-30" version="1" fragment="single">MEGILTDVSDPNIVLENITSREKYLNAKCPEKSRVPTSTKKQSKHEELRKATSHKNYNDLTRETFIDRMLEQPVERGVVSRVAKDLNINYRTALRWWHLYNETEEVAYKKSEQNTKRKSSFTAAHNAHIYELIDNDPQLVSDDIIDSLTKSFKDFKISKSQLNNHLRNAMLIAIKKPVFEAEMRNSAGSLQTRYEWFMKWRNSDLDYTENCVFIDEAGFQINMRNNWARSKSGSIAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MV62</accession>
    <name>A0A1C7MV62_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_11304</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001889">
        <property type="protein sequence ID" value="OBZ80647.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7MV62"/>
    <dbReference type="InParanoid" id="A0A1C7MV62"/>
    <dbReference type="OrthoDB" id="2288643at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004190">
        <property type="term" value="F:aspartic-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.70.10">
        <property type="entry name" value="Acid Proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001969">
        <property type="entry name" value="Aspartic_peptidase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021109">
        <property type="entry name" value="Peptidase_aspartic_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50630">
        <property type="entry name" value="Acid proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00141">
        <property type="entry name" value="ASP_PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0064">Aspartyl protease</keyword>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0645">Protease</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="54"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="54"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="336"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022750"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ80647.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="336" mass="36832" checksum="F70578B3E0AC7FFB" modified="2016-11-30" version="1" fragment="single">MARLSFDISTIYELDDRINITLKSVSTEKKVSLDYICSKARNLYNQARVQYETSSGSKRSFSLPNTQANRDQGSSSDHKPVRFSKPASGSAVSEKKPKTGMFCAFHRVTTHSTEECQARKRGDAPKNKNNCRHCGSPGWTPAHRCGSVVRSGPSDKDITVRVASVQDKKAVAAWSDFVQSSPTSASVESAAAFPGSAPSSSHVHSPGPSQAIDNMDIDSYEEFLMITIQAQKCKSNTQLMQKLKLESNSILLPVTIENVQTYALLDTGATRSSVTPSFLRSLDTSIPLTKATGKIQLGHKDASVXRIGFTPLKVFYNKIDITHTFEVFAFFSHENV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MV70</accession>
    <name>A0A1C7MV70_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Hybrid signal transduction histidine kinase J</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">dhkJ_1</name>
        <name evidence="4" type="ORF">A0J61_11602</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01002240">
        <property type="protein sequence ID" value="OBZ80349.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MV70"/>
    <dbReference type="STRING" id="101091.A0A1C7MV70"/>
    <dbReference type="InParanoid" id="A0A1C7MV70"/>
    <dbReference type="OrthoDB" id="10266508at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06225">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.120.1530:FF:000002">
        <property type="entry name" value="Two-component osmosensing histidine kinase"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1530">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.950">
        <property type="entry name" value="Methyl-accepting chemotaxis protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003660">
        <property type="entry name" value="HAMP_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45339">
        <property type="entry name" value="HYBRID SIGNAL TRANSDUCTION HISTIDINE KINASE J"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45339:SF1">
        <property type="entry name" value="HYBRID SIGNAL TRANSDUCTION HISTIDINE KINASE J"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00672">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SMART" id="SM00304">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF58104">
        <property type="entry name" value="Methyl-accepting chemotaxis protein (MCP) signaling domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50885">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="2" id="KW-0902">Two-component regulatory system</keyword>
    <feature type="domain" description="HAMP" evidence="3">
        <location>
            <begin position="21"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="domain" description="HAMP" evidence="3">
        <location>
            <begin position="113"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="domain" description="HAMP" evidence="3">
        <location>
            <begin position="205"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="domain" description="HAMP" evidence="3">
        <location>
            <begin position="297"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="domain" description="HAMP" evidence="3">
        <location>
            <begin position="389"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="458"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OBZ80349.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="458" mass="48701" checksum="076D467BE54A097E" modified="2016-11-30" version="1" fragment="single">MVPNVAGTWFELTDNVNIMAANLTNQVRSIAEVTKAVALGDLSKKIEVESGGEILDLKVTVNSMVDQLRIFASEVTRVAREVGTEGKLGGQATVEGVAGTWNELTDNVNTMAANLTTQVRSIAQVTKAVANGDLSKKIEVQTNGEILELKDTVNDMVDQLRVFAAEVTRVAKEVGTEGKLGGQAKVEGVAGTWMDLTDNVNTMAANLTTQVRSIAQVTKAVALGDLSKKIEVESGGEILELKDIVNNMVDQLRIFASEVTRVSKEVGTEGKLGGQAVVQGVAGTWMDLTDNVNQMAANLTNQVRSIAEVTKAVARGDLSKKIEVESGGEILDLKNIVNNMVDQLNVFAAEVTRVAKEVGTEGKLGGQARVPNVDGTWKDLTDNVNTMATNLTNQVRSIAEVTKAVALGDLSKKIEVESGGEILDLKNIVNNMVDQLNVFASEVSRVAREVGTEGKLGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MVD7</accession>
    <name>A0A1C7MVD7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_11110</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001683">
        <property type="protein sequence ID" value="OBZ80841.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MVD7"/>
    <dbReference type="InParanoid" id="A0A1C7MVD7"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="43"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ80841.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="67" mass="7317" checksum="B2DBDCBB227A73D5" modified="2016-11-30" version="1">MVEKLGESYSLEGRAQVPIPKFNAVDDPSQVIPSTVSASERSLFCSCRGCLATVVLFSFALWSHLLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MVN5</accession>
    <name>A0A1C7MVN5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">ATP-dependent DNA helicase</fullName>
            <ecNumber evidence="1">5.6.2.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">pif1_6</name>
        <name evidence="3" type="ORF">A0J61_11082</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="5.6.2.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the helicase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.6.2.3" evidence="1"/>
    <dbReference type="EMBL" id="LUGH01001655">
        <property type="protein sequence ID" value="OBZ80870.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MVN5"/>
    <dbReference type="STRING" id="101091.A0A1C7MVN5"/>
    <dbReference type="InParanoid" id="A0A1C7MVN5"/>
    <dbReference type="OrthoDB" id="2325450at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043139">
        <property type="term" value="F:5'-3' DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000723">
        <property type="term" value="P:telomere maintenance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010285">
        <property type="entry name" value="DNA_helicase_pif1-like_DEAD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051055">
        <property type="entry name" value="PIF1_helicase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47642">
        <property type="entry name" value="ATP-DEPENDENT DNA HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05970">
        <property type="entry name" value="PIF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0227">DNA damage</keyword>
    <keyword evidence="1" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="1" id="KW-0234">DNA repair</keyword>
    <keyword evidence="1 3" id="KW-0347">Helicase</keyword>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA helicase Pif1-like DEAD-box helicase" evidence="2">
        <location>
            <begin position="7"/>
            <end position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU363044"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF05970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ80870.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="276" mass="31380" checksum="2A43FE97C49F7F34" modified="2016-11-30" version="1">MLERHYKIEDDKVFELAPTGVAAYNISGQTLHRFFGLTNVALVPNFALLDRYVEQYPRMILLIDEYSMIGSKMPESISEALTKVTNRNRNMGGIRTIFFGDIVQLLPVKANEGKIWEFPTYNTVNRYQLRIPVKQNDAYFVSILNKIKTYKFDQSVIEFINSRTVAKSESSSRCLRLHTTLERVTAANERDYNSFPGGGKSYEAQDNFTGTAGTARATLNETRLVQRLPLNKKMPLMLIQNLNLQGGWVNGTIAQIEYLEDGNICLRKMSNNSNSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MW45</accession>
    <name>A0A1C7MW45_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_10917</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001511">
        <property type="protein sequence ID" value="OBZ81033.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MW45"/>
    <dbReference type="InParanoid" id="A0A1C7MW45"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="27"/>
            <end position="48"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ81033.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="119" mass="13698" checksum="9F3A8D66A58E6EE8" modified="2016-11-30" version="1">MVAKKKELTATVNLCLDKLNRLEAREGHELHQQANSSGPVGTSDVPIYRPQISRSSNNKLKQKLNHFIQQWLGDAVIVNHNDTSESRREKEYRLEMYESSLRQLGKIALDKLIMKLQAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MWI8</accession>
    <name>A0A1C7MWI8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Helitron helicase-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_11152</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001717">
        <property type="protein sequence ID" value="OBZ80799.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MWI8"/>
    <dbReference type="STRING" id="101091.A0A1C7MWI8"/>
    <dbReference type="InParanoid" id="A0A1C7MWI8"/>
    <dbReference type="OrthoDB" id="2282872at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025476">
        <property type="entry name" value="Helitron_helicase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14214">
        <property type="entry name" value="Helitron_like_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helitron helicase-like" evidence="1">
        <location>
            <begin position="58"/>
            <end position="154"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF14214"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ80799.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="157" mass="18260" checksum="998B5337E8FABF04" modified="2016-11-30" version="1">MVKRIDFLLFMERKRQLLSSASHVTTVMRMSKARLKNPLRVHNILENDGLSDIMKKGLAFQVLQKVRSSPAYWKNERINVMAMVRQLGISTLFVTLSAAEAKWPELLVILKIVLDNEVLTKNEVNELSREEKARLIQSDSITCARYFNRRMRILKNT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MWW9</accession>
    <name>A0A1C7MWW9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_10624</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001275">
        <property type="protein sequence ID" value="OBZ81327.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MWW9"/>
    <dbReference type="STRING" id="101091.A0A1C7MWW9"/>
    <dbReference type="InParanoid" id="A0A1C7MWW9"/>
    <dbReference type="OrthoDB" id="2275976at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="112"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ81327.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="112" mass="13334" checksum="83FCBBDC695A01DB" modified="2016-11-30" version="1" fragment="single">MAQYAVNAQFRHLHSTRAFTAMFFRQPNPLTDYTKVEPTLSFEKSEHKRINEQLKHVKEVVVPALHEHIKDRQQTDHQKYLKSHNIRADKYPLHSKVMIVNVNRNGKTEPRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MWZ8</accession>
    <name>A0A1C7MWZ8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 15">Elongator complex protein 3</fullName>
            <ecNumber evidence="15">2.3.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="19" type="primary">elp3</name>
        <name evidence="19" type="ORF">A0J61_10604</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="19 20" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19 20">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="15">Catalytic tRNA acetyltransferase subunit of the elongator complex, which is required for multiple tRNA modifications, including mcm5U (5-methoxycarbonylmethyl uridine), mcm5s2U (5-methoxycarbonylmethyl-2-thiouridine), and ncm5U (5-carbamoylmethyl uridine). In the elongator complex, acts as a tRNA uridine(34) acetyltransferase by mediating formation of carboxymethyluridine in the wobble base at position 34 in tRNAs.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>uridine(34) in tRNA + acetyl-CoA + S-adenosyl-L-methionine + H2O = 5-(carboxymethyl)uridine(34) in tRNA + 5'-deoxyadenosine + L-methionine + CoA + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:61020"/>
            <dbReference type="Rhea" id="RHEA-COMP:10407"/>
            <dbReference type="Rhea" id="RHEA-COMP:11727"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17319"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="ChEBI" id="CHEBI:74882"/>
            <dbReference type="EC" id="2.3.1.311"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="14">
            <dbReference type="Rhea" id="RHEA:61021"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="15 16">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="15 16">Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1">tRNA modification; 5-methoxycarbonylmethyl-2-thiouridine-tRNA biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 15">Belongs to the ELP3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="19">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.-" evidence="15"/>
    <dbReference type="EMBL" id="LUGH01001263">
        <property type="protein sequence ID" value="OBZ81347.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MWZ8"/>
    <dbReference type="FunCoup" id="A0A1C7MWZ8">
        <property type="interactions" value="765"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7MWZ8"/>
    <dbReference type="InParanoid" id="A0A1C7MWZ8"/>
    <dbReference type="OrthoDB" id="10265243at2759"/>
    <dbReference type="UniPathway" id="UPA00988"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033588">
        <property type="term" value="C:elongator holoenzyme complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106261">
        <property type="term" value="F:tRNA uridine(34) acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140018">
        <property type="term" value="P:regulation of cytoplasmic translational fidelity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002926">
        <property type="term" value="P:tRNA wobble base 5-methoxycarbonylmethyl-2-thiouridinylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd01335">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.630.30:FF:000003">
        <property type="entry name" value="Elongator complex protein 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039661">
        <property type="entry name" value="ELP3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034687">
        <property type="entry name" value="ELP3-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056591">
        <property type="entry name" value="ELP3-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006638">
        <property type="entry name" value="Elp3/MiaA/NifB-like_rSAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032432">
        <property type="entry name" value="Radical_SAM_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007197">
        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058240">
        <property type="entry name" value="rSAM_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01211">
        <property type="entry name" value="ELP3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11135:SF0">
        <property type="entry name" value="ELONGATOR COMPLEX PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11135">
        <property type="entry name" value="HISTONE ACETYLTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23613">
        <property type="entry name" value="ELP3_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04055">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16199">
        <property type="entry name" value="Radical_SAM_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005669">
        <property type="entry name" value="Hist_AcTrfase_ELP3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01086">
        <property type="entry name" value="elongater_protein-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00344">
        <property type="entry name" value="ELP3-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00029">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00729">
        <property type="entry name" value="Elp3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102114">
        <property type="entry name" value="Radical SAM enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51918">
        <property type="entry name" value="RADICAL_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="13 15" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="11 16" id="KW-0408">Iron</keyword>
    <keyword evidence="12 15 16" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="9 15 16" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="7 15" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="6 15" id="KW-0808">Transferase</keyword>
    <keyword evidence="8 15" id="KW-0819">tRNA processing</keyword>
    <keyword evidence="5 15" id="KW-0820">tRNA-binding</keyword>
    <feature type="domain" description="Radical SAM core" evidence="18">
        <location>
            <begin position="83"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="domain" description="N-acetyltransferase" evidence="17">
        <location>
            <begin position="397"/>
            <end position="548"/>
        </location>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="100"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="110"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="113"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00020266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00047372"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PIRNR" id="PIRNR005669"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PIRSR" id="PIRSR005669-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS51918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="OBZ81347.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="548" mass="61784" checksum="79F997753EF8DA46" modified="2016-11-30" version="1">MSSKTKKGGPSQAELLVKTCSEIVAELVAAVEAGKDVNLNGVKNRAARRNKLQNQPKLVEIIAAIPEQHKAALLPKLKAKPVRTASGIAVVAVMCKPHRCPHIAMTGNICVYCPGGPDSDFEYSTQSYTGYEPTSMRAIRARYDPYEQSRGRVDQLRSLGHSVDKVEYIIMGGTFMSLAEEYRNWFIQNLHDALSGHTSNNLDEAVRYSQQSQTKCIGITIETRPDYCLKPHLSQMLRYGCTRLEVGVQSVYEDVARDTNRGHTVKAVTECFQMAKDAGFKVVSHMMPDLPNVGMERDIEQFKEYFENPAFRSDGLKIYPTLVIRGTGLYELWRTKRYQNYTPNALVDLVARILALVPPWTRIYRVQRDIPMPLVSSGVEHGNLRELALNRMKDLGTECRDVRTREVGITEIHQKIKPDQVELIRRDYVANGGWETFLSYEDPHQDILVGLLRLRKCSSQAFRPELTSGPTSIVRELHVYGSVVPMHDRDPTKFQHQGFGTLLMEEAARIAKEEHGSVKLSVISGVGVRDYYAKLGYELDGPYMSKML</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MXA9</accession>
    <name>A0A1C7MXA9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_10892</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001490">
        <property type="protein sequence ID" value="OBZ81059.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MXA9"/>
    <dbReference type="InParanoid" id="A0A1C7MXA9"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="30"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ81059.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="103" mass="11448" checksum="E4FEA66C73D55EE6" modified="2016-11-30" version="1">MQEMMTKQNELVATLKICLDKLNRLEAREASTGREIHQEANSSGPLGISDVPIYRPQISGSSDKKLKQKVDHFIQQWLGDAVMVNANDTSESQRKKGIPPGDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MXQ4</accession>
    <name>A0A1C7MXQ4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Transcription factor cbf11</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">cbf11_0</name>
        <name evidence="9" type="ORF">A0J61_10383</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the Su(H) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001147">
        <property type="protein sequence ID" value="OBZ81568.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7MXQ4"/>
    <dbReference type="InParanoid" id="A0A1C7MXQ4"/>
    <dbReference type="OrthoDB" id="5600360at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001228">
        <property type="term" value="F:DNA-binding transcription activator activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.80.10.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1450">
        <property type="entry name" value="LAG1, DNA binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015350">
        <property type="entry name" value="Beta-trefoil_DNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036358">
        <property type="entry name" value="BTD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040159">
        <property type="entry name" value="CLS_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008967">
        <property type="entry name" value="p53-like_TF_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015351">
        <property type="entry name" value="RBP-J/Cbf11/Cbf12_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037095">
        <property type="entry name" value="RBP-J/Cbf11_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10665">
        <property type="entry name" value="RECOMBINING BINDING PROTEIN SUPPRESSOR OF HAIRLESS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09270">
        <property type="entry name" value="BTD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09271">
        <property type="entry name" value="LAG1-DNAbind"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM01268">
        <property type="entry name" value="BTD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01267">
        <property type="entry name" value="LAG1_DNAbind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110217">
        <property type="entry name" value="DNA-binding protein LAG-1 (CSL)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49417">
        <property type="entry name" value="p53-like transcription factors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="RBP-J/Cbf11/Cbf12 DNA binding" evidence="7">
        <location>
            <begin position="81"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="domain" description="Beta-trefoil DNA-binding" evidence="8">
        <location>
            <begin position="203"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="304"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009704"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM01267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM01268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OBZ81568.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="304" mass="34460" checksum="1023B3186865483F" modified="2016-11-30" version="1" fragment="single">MTEQLFMTPMESLLSAIDDAKPIYLPNPHNKQKRARSPTPQQMSIESILDHEPSCKRHQPYYRPLSPPPQSPPHSTYDKTIVTCYHASVAQKSYGTEKRFLCPPPIVMMSNPVHHHHQPMVSMTVVXETGDRQLEQRTLLDEQLKGSFKYLFVNGTAKAKQFCLRVSLSHQQQQQHYASFFSQPISIISKPSKKTAKARNVSTCLFTNSHVSLFNRINSQTVRTKYLTTEDKQLCAKHASWSPFEIIVVRQPNQAVNPDNHSVSVPITYGTEIILKDVQTAVSSPPLIIRKVDKGQVVHHAYGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MXW0</accession>
    <name>A0A1C7MXW0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Putative RNA-binding protein C17H9.04c</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">A0J61_10288</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001104">
        <property type="protein sequence ID" value="OBZ81663.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MXW0"/>
    <dbReference type="FunCoup" id="A0A1C7MXW0">
        <property type="interactions" value="67"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7MXW0"/>
    <dbReference type="InParanoid" id="A0A1C7MXW0"/>
    <dbReference type="OrthoDB" id="448399at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000175">
        <property type="term" value="F:3'-5'-RNA exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06133">
        <property type="entry name" value="ERI-1_3'hExo_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.1060.10">
        <property type="entry name" value="Zinc finger, RanBP2-type"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047201">
        <property type="entry name" value="ERI-1_3'hExo-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013520">
        <property type="entry name" value="Ribonucl_H"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001876">
        <property type="entry name" value="Znf_RanBP2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036443">
        <property type="entry name" value="Znf_RanBP2_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23111:SF40">
        <property type="entry name" value="RNA-BINDING PROTEIN INVOLVED IN HETEROCHROMATIN ASSEMBLY-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23111">
        <property type="entry name" value="ZINC FINGER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00929">
        <property type="entry name" value="RNase_T"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00641">
        <property type="entry name" value="Zn_ribbon_RanBP"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00479">
        <property type="entry name" value="EXOIII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00547">
        <property type="entry name" value="ZnF_RBZ"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90209">
        <property type="entry name" value="Ran binding protein zinc finger-like"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01358">
        <property type="entry name" value="ZF_RANBP2_1"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50199">
        <property type="entry name" value="ZF_RANBP2_2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RRM" evidence="7">
        <location>
            <begin position="318"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="domain" description="RanBP2-type" evidence="8">
        <location>
            <begin position="419"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="domain" description="RanBP2-type" evidence="8">
        <location>
            <begin position="463"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="domain" description="RanBP2-type" evidence="8">
        <location>
            <begin position="559"/>
            <end position="590"/>
        </location>
    </feature>
    <feature type="domain" description="RanBP2-type" evidence="8">
        <location>
            <begin position="726"/>
            <end position="755"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="592"/>
            <end position="639"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="73"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="592"/>
            <end position="621"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00322"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OBZ81663.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="772" mass="84054" checksum="F8989BBE6BCD8F51" modified="2016-11-30" version="1">MEAQAELDRKRKADDESLEENSVKRPFIQNNEYDTTEPFPKAEEAASESATETQAVDDESCLVKLEHKDEAEQTTQQPTSSSTTKQEPATSTNIPFDRLIFFHLEATCDENPTNPAAVQVTKENSEVIEMSFVVVDGASLEVLHQQSIYVKPERTPLTPFCSEVTGIKWSMLEHAGSLSDAINQLDDYIQKEIEAEKKSFCFVTHGGWVLRIQLPREARDKNLTLPNYMAFCRMFDLKQEIQRWQVHHPEISLRSTSLRDLCEIFEIKRVTDQTVGLNATLTTLKIVRHLTRFRHSDVFVHPIDTNADLKQFKKEESKVIHLAGLPFEVTQGELEAWFSSNGLRPTTMWMIQPSDSSKPSISGFVVFQLHDDAMRALSLNGRCLGDRPIEVCPSSSRVIDAAGNMLVPFPLQAKSRQLRPGDWNCYNCSFHNFASRLYCFKCNTKNPNPGPQAGQGPPVQPFTRGDWMCPNPSCNFHNYASRMQCKKCGHMKPMGNKKPIKMGKIDSGQPPYHMSMHNMPAGAAGAAGAGGPSGDVNNNGGGYHGGYSSRPHHHHISFRPGDWYCPNANCGFQNFASRNSCFRCHTPNPNLSQIPSSSTQSQIGSVPAPAPNASSAAVASAQHSQYSPHQPGYGYSDSNANYQSNTGYVGNNGGVAGGNNNNSGGYGYGQPGGGYGGQNSSYAAPGGGYGGGGNGSGYAYGGGGYAYGGAHQNGPPGSTPGTTQFRAGDWICPSCSSHNFASRFHCLKCSTSKPFNPTGGPPSAVGTPYKRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MY76</accession>
    <name>A0A1C7MY76_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Vacuolar protein sorting-associated protein 72</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">VPS72</name>
        <name evidence="4" type="ORF">A0J61_10196</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the VPS72/YL1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001068">
        <property type="protein sequence ID" value="OBZ81752.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MY76"/>
    <dbReference type="FunCoup" id="A0A1C7MY76">
        <property type="interactions" value="508"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7MY76"/>
    <dbReference type="InParanoid" id="A0A1C7MY76"/>
    <dbReference type="OrthoDB" id="78296at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013272">
        <property type="entry name" value="Vps72/YL1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046757">
        <property type="entry name" value="YL1_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13275:SF4">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 72 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13275">
        <property type="entry name" value="YL-1 PROTEIN TRANSCRIPTION FACTOR-LIKE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05764">
        <property type="entry name" value="YL1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08265">
        <property type="entry name" value="YL1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00993">
        <property type="entry name" value="YL1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Vps72/YL1 C-terminal" evidence="3">
        <location>
            <begin position="287"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="23"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="65"/>
            <end position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00993"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OBZ81752.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="349" mass="40337" checksum="47C54E6917AC6212" modified="2016-11-30" version="1">MSLVQERERRANAGSRMRALLNQEEDMEELFEYQEDDEEDAAFSAAEEEEDKVDSDFDLDSSEGEQEHIEEGRQMDKQIALDEKKARKATTFNPSSTVPKPATKKPAEKRKRVFVEELTEERTIRYSSRKNTILNRILVEGQLREHEKRRALQPKRDRPVVNKLTQEELLAEAAITEEANKNSLLEWQQREAERKENAKKTDIKGVVGPFVRYHSFKDALQVKSADSETIVYDLDAMGRTLMTFVEEEDLQEYDPEEREREVGIDQLGMIHHLSEWFEKLPKPNKPIVCPINGDLAKYRDPSSDVPYANVQSYRAIKSCLNHQTRWSPISHLYLGRLPSAKGVPEGFDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MYR9</accession>
    <name>A0A1C7MYR9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Putative V-type proton ATPase proteolipid subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">vma16</name>
        <name evidence="13" type="ORF">A0J61_10033</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Proton-conducting pore forming of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments.</text>
    </comment>
    <comment type="function">
        <text evidence="9">Proton-conducting pore forming subunit of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments.</text>
    </comment>
    <comment type="subunit">
        <text evidence="10 11">V-ATPase is a heteromultimeric enzyme composed of a peripheral catalytic V1 complex (components A to H) attached to an integral membrane V0 proton pore complex (components: a, c, c', c'', d, e, f and VOA1). The decameric c-ring forms the proton-conducting pore, and is composed of eight proteolipid subunits c, one subunit c' and one subunit c''.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the V-ATPase proteolipid subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001008">
        <property type="protein sequence ID" value="OBZ81918.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MYR9"/>
    <dbReference type="FunCoup" id="A0A1C7MYR9">
        <property type="interactions" value="137"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7MYR9"/>
    <dbReference type="InParanoid" id="A0A1C7MYR9"/>
    <dbReference type="OrthoDB" id="10264021at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000220">
        <property type="term" value="C:vacuolar proton-transporting V-type ATPase, V0 domain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008553">
        <property type="term" value="F:P-type proton-exporting transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046961">
        <property type="term" value="F:proton-transporting ATPase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007035">
        <property type="term" value="P:vacuolar acidification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd18177">
        <property type="entry name" value="ATP-synt_Vo_c_ATP6F_rpt1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18178">
        <property type="entry name" value="ATP-synt_Vo_c_ATP6F_rpt2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.120.610:FF:000002">
        <property type="entry name" value="V-type proton ATPase proteolipid subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.610">
        <property type="entry name" value="lithium bound rotor ring of v- atpase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002379">
        <property type="entry name" value="ATPase_proteolipid_c-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000245">
        <property type="entry name" value="ATPase_proteolipid_csu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035921">
        <property type="entry name" value="F/V-ATP_Csub_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10263">
        <property type="entry name" value="V-TYPE PROTON ATPASE PROTEOLIPID SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00137">
        <property type="entry name" value="ATP-synt_C"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00122">
        <property type="entry name" value="VACATPASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81333">
        <property type="entry name" value="F1F0 ATP synthase subunit C"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="7 11" id="KW-0406">Ion transport</keyword>
    <keyword evidence="8 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 11" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="31"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="71"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="114"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="157"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="193"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="domain" description="V-ATPase proteolipid subunit C-like" evidence="12">
        <location>
            <begin position="76"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="domain" description="V-ATPase proteolipid subunit C-like" evidence="12">
        <location>
            <begin position="160"/>
            <end position="217"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00045519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00046480"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU363060"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF00137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="OBZ81918.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="226" mass="23670" checksum="D636B1A2EDE83F37" modified="2016-11-30" version="1">MSGSSYGPLTYWAVHKNITSIIMSGSSYGPLTYWAGLSISLLTIVGLYMLFTGSGEEFNVGRLLQETSPYAWALTGMGLCIGLSVTGAAWGIFITGSALLGAAVKTPRIQSRNLISIIFCEVVAIYGVIMAIVYSAKLSDVPPEGLYTTSNYFTGHAIFWGGLTVGICNLLCGMSVGVTGSSAALADAQNPELFVKVLVVEIFGSVLGLFGLIVGLLTTGKAADFH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-06-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MYU1</accession>
    <name>A0A1C7MYU1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_11666</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01002317">
        <property type="protein sequence ID" value="OBZ80284.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MYU1"/>
    <dbReference type="InParanoid" id="A0A1C7MYU1"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ80284.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="27" mass="3281" checksum="FA0AE3291AADCD62" modified="2016-11-30" version="1" fragment="single">MNEEVAPYLEFFSKIVTTEYNNKEDLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MZ33</accession>
    <name>A0A1C7MZ33_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_09831</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000949">
        <property type="protein sequence ID" value="OBZ82120.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MZ33"/>
    <dbReference type="InParanoid" id="A0A1C7MZ33"/>
    <dbReference type="OrthoDB" id="1684102at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ82120.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="306" mass="35272" checksum="2527E021C538DE3F" modified="2016-11-30" version="1">MKWRFYNKEIKLHTGYADFRYGAFVPRWKVQSFLTQLGKSGLGSDSIRHAEHYFGIWMNQYPWLLSNPPYMANGDKATEKNVAFDTSLDHYTYDAVRHLQRSLTADQSEAPQDYFERTEEPPVLSYRDVRSSCANDRCLFISNMDPFVSPQQVPFDYQNITSISKLEQAYNGLLSLPGSIEWEEHSFHRAADSDPNSCWNTIHAPRQKDYFGLILVGTANTKTVVIHTPQKIQNPERQLEVSVLQSDSEWTRCKITDQTIQNTDRITLDLHCPANVQFFRAIKVAFKKQQAEPFQICGLSIDTLSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MZY6</accession>
    <name>A0A1C7MZY6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_11277</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001859">
        <property type="protein sequence ID" value="OBZ80674.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MZY6"/>
    <dbReference type="InParanoid" id="A0A1C7MZY6"/>
    <dbReference type="OrthoDB" id="2202621at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="265"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ80674.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="265" mass="29439" checksum="FD4998B48945F996" modified="2016-11-30" version="1" fragment="single">MPAFKCSGCQCLFASHSLLRIHQRETGCFRSVIESSLAAFTQTRNSSSSSALGEDIPDFEGVSPVASVALNNPAEIDEADENTAAAQVEEEASFAEVNAEENSVERGPIVQQWFDDAQVEDCDDVAMQLMRVFDMNKISRQDQRNIFKLVILGTLTGKHFKTPDTYGRIIIKNSSTTVRYDICPNGCYLYPVGDSSEVTCPNGNCDVARYRDATAINIENRDPTMPPPALVAKKQMAYTSISQALTQLYVDDERSEMLSYRDHFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N0C4</accession>
    <name>A0A1C7N0C4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF6729 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_09343</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000829">
        <property type="protein sequence ID" value="OBZ82605.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N0C4"/>
    <dbReference type="InParanoid" id="A0A1C7N0C4"/>
    <dbReference type="OrthoDB" id="2287572at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046616">
        <property type="entry name" value="DUF6729"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20499">
        <property type="entry name" value="DUF6729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF6729" evidence="1">
        <location>
            <begin position="139"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="307"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF20499"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ82605.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="307" mass="35290" checksum="F48F0B256390B5C3" modified="2016-11-30" version="1" fragment="single">MKSNQKHKITKSSARQFSIGRFSATKGFDSSQQTIQNAFDRIQNNVDLSSASASQAADSSVEIVVTDYSESGVIATALTTEEQKHEQNEQVEEEDLEEDIEEFISVSLPEESATSLYLESIQNRLSREDYPSVYARGTFWIEPMMPFFMLKKNKKIEFLHHLQVFLWIPHLLLSEWLAAIHCPCCKSKMETKEFNKQPHARKIVDIDSCFHLMSMRYRCLSPGCGKTINAHDSQVIKQLTYELQFEFPAILTHKGDVFKAVADLLRPCIQNPIGPKRFQKILVELHHLCHDCIELQYLLSVYRKRSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N0K2</accession>
    <name>A0A1C7N0K2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Golgi pH regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">GPR89</name>
        <name evidence="9" type="ORF">A0J61_09275</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000814">
        <property type="protein sequence ID" value="OBZ82675.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N0K2"/>
    <dbReference type="STRING" id="101091.A0A1C7N0K2"/>
    <dbReference type="InParanoid" id="A0A1C7N0K2"/>
    <dbReference type="OrthoDB" id="264392at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025969">
        <property type="entry name" value="ABA_GPCR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022535">
        <property type="entry name" value="Golgi_pH-regulator_cons_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015672">
        <property type="entry name" value="GPHR/GTG"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15948">
        <property type="entry name" value="G-PROTEIN COUPLED RECEPTOR 89-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15948:SF0">
        <property type="entry name" value="GOLGI PH REGULATOR A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12430">
        <property type="entry name" value="ABA_GPCR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12537">
        <property type="entry name" value="GPHR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="15"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="49"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="86"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="214"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="274"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="312"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="355"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="domain" description="Golgi pH regulator conserved" evidence="8">
        <location>
            <begin position="80"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="domain" description="Abscisic acid G-protein coupled receptor-like" evidence="7">
        <location>
            <begin position="206"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="127"/>
            <end position="154"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF12430"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF12537"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OBZ82675.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="410" mass="47798" checksum="B06F22FD4E00A6C0" modified="2016-11-30" version="1">MTLLNIRSRSHYWQLNLYLILLLVIIVVPWFQLYTFFHSTQACRKRTSVVFATCFWVGYLCLFDQIQHHSKSDHTWLELGIIRVSVIGISLISILSGFGVVSTPYATWLSYRRHVSDQDYQVAKRAYQQTESMIKDKKDLLDQLQSNKQSTSHEDASLFTKLKTTLFHPPDEMVALQTEVDQMTILANQMKSDLEELERSHAKSKYAQTWRGKLWRLIELLFAIYCIYRLISTTVNVVLRRTGSSDPITTMIFIVLSQFGDSVQINTEFWSQQLSFWFAGIIVVGSIRGFLKLLIRILDVFQWNVTLSINHLLLLTAHIMGMYFLSSILMMQLSLPTEYRYLLSSSVEFDFFRRWSDVIFVISSLISLAVTYVVYSTHDVKSMAQDFWDVEMMQLESGDRTSSHRLEKQM</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N0W7</accession>
    <name>A0A1C7N0W7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_09204</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000796">
        <property type="protein sequence ID" value="OBZ82750.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N0W7"/>
    <dbReference type="InParanoid" id="A0A1C7N0W7"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="39"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="39"/>
            <end position="48"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ82750.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="61" mass="6795" checksum="93F348EB38CCDDBA" modified="2016-11-30" version="1">MFDSELAQTVQILFSEVLVDGLGCLAKRVYSPLIAKSSNTDTVSQTKRGISKHRIEEKQAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N102</accession>
    <name>A0A1C7N102_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="11">DNA-(Apurinic or apyrimidinic site) lyase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">apeA</name>
        <name evidence="11" type="ORF">A0J61_09191</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="6 8">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <cofactor evidence="6 8">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <text evidence="6 8">Probably binds two magnesium or manganese ions per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 8">Belongs to the DNA repair enzymes AP/ExoA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000794">
        <property type="protein sequence ID" value="OBZ82762.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N102"/>
    <dbReference type="STRING" id="101091.A0A1C7N102"/>
    <dbReference type="InParanoid" id="A0A1C7N102"/>
    <dbReference type="OrthoDB" id="498125at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003906">
        <property type="term" value="F:DNA-(apurinic or apyrimidinic site) endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008311">
        <property type="term" value="F:double-stranded DNA 3'-5' DNA exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008081">
        <property type="term" value="F:phosphoric diester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006284">
        <property type="term" value="P:base-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd09087">
        <property type="entry name" value="Ape1-like_AP-endo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.10.10">
        <property type="entry name" value="Endonuclease/exonuclease/phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004808">
        <property type="entry name" value="AP_endonuc_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020847">
        <property type="entry name" value="AP_endonuclease_F1_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036691">
        <property type="entry name" value="Endo/exonu/phosph_ase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005135">
        <property type="entry name" value="Endo/exonuclease/phosphatase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00195">
        <property type="entry name" value="exoDNase_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00633">
        <property type="entry name" value="xth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22748">
        <property type="entry name" value="AP ENDONUCLEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22748:SF6">
        <property type="entry name" value="DNA-(APURINIC OR APYRIMIDINIC SITE) ENDONUCLEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03372">
        <property type="entry name" value="Exo_endo_phos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56219">
        <property type="entry name" value="DNase I-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00726">
        <property type="entry name" value="AP_NUCLEASE_F1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51435">
        <property type="entry name" value="AP_NUCLEASE_F1_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0227">DNA damage</keyword>
    <keyword evidence="8" id="KW-0234">DNA repair</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="11" id="KW-0456">Lyase</keyword>
    <keyword evidence="4 6 8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6" id="KW-0464">Manganese</keyword>
    <keyword evidence="2 6 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Endonuclease/exonuclease/phosphatase" evidence="10">
        <location>
            <begin position="76"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="active site" evidence="5">
        <location>
            <position position="178"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor/acceptor" evidence="5">
        <location>
            <position position="218"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="5">
        <location>
            <position position="325"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="78"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="106"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="218"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="220"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="324"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="325"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="7">
        <location>
            <position position="220"/>
        </location>
    </feature>
    <feature type="site" description="Important for catalytic activity" evidence="7">
        <location>
            <position position="298"/>
        </location>
    </feature>
    <feature type="site" description="Interaction with DNA substrate" evidence="7">
        <location>
            <position position="325"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007092"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR604808-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR604808-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR604808-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU362131"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF03372"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="OBZ82762.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="340" mass="38956" checksum="65D647AF931EBAAD" modified="2016-11-30" version="1">MAKTVQTQSTTVKLARKRSHSTEPVEQTEELKKPKLASKPKAKAWEPFDPSLPNNMTFPEKFNIPVKPEGSIKITSYNVAGLQACIKKGFNRYIDAEDADIVCIQEHKLSAALSTAVNDKIYKYRYWGCDEKKGYAGVAFFSKFKPEKIIYGIPGYEQKTRGRVISLTFPSFTIIGCYVPNAGDKLVRLPERRVFNEHMEKYIRSLQKEGKSVIWTGDLNVAHTENDLARPETNQRSAGFTIEERTDFSKVLSPSEEDSSLPGLIDTWRHFNPEQKGHYTFYGYRFKCREKLMGWRLDYFTVTPDLMDHVVSSEIRHEGWGASDHVPLVLTLKDVKMQQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N1D2</accession>
    <name>A0A1C7N1D2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Pre-mRNA-splicing factor cwf25</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">cwf25</name>
        <name evidence="10" type="ORF">A0J61_10777</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the CWC25 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001385">
        <property type="protein sequence ID" value="OBZ81174.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N1D2"/>
    <dbReference type="InParanoid" id="A0A1C7N1D2"/>
    <dbReference type="OrthoDB" id="21123at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005684">
        <property type="term" value="C:U2-type spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019339">
        <property type="entry name" value="CIR_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022209">
        <property type="entry name" value="CWC25"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051376">
        <property type="entry name" value="CWC25_splicing_factor"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16196">
        <property type="entry name" value="CELL CYCLE CONTROL PROTEIN CWF25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16196:SF0">
        <property type="entry name" value="PRE-MRNA-SPLICING FACTOR CWC25 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10197">
        <property type="entry name" value="Cir_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12542">
        <property type="entry name" value="CWC25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01083">
        <property type="entry name" value="Cir_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="6" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0747">Spliceosome</keyword>
    <feature type="domain" description="CBF1-interacting co-repressor CIR N-terminal" evidence="9">
        <location>
            <begin position="11"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="47"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="108"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="156"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="47"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="130"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="170"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="190"/>
            <end position="234"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM01083"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OBZ81174.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="243" mass="28949" checksum="26E607AC4DA02F79" modified="2016-11-30" version="1">MGSSDLNLKKSWHPATFKNQERVWKEEQKRKEEDRKLDQLKKELAEERQLQDLQRMQEEAGTKKRSNKLDWMYASPNANLNGSANNTMEDYLLGKKNVDDLLRAKQKEQVQAATAAEENRFTLSNANANSERDIQSKIREDPLLMIKKREQMALKAIVENPLKLKELKKKEKKKKKSSEHKHHHHSSSRSRHEERGSYRDDHSQRRHDTRESSXRHRHDSRERSSRYRDEDDSRRKRRSASPY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N2D9</accession>
    <name>A0A1C7N2D9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Hydroxymethylglutaryl-CoA synthase</fullName>
            <shortName evidence="5">HMG-CoA synthase</shortName>
            <ecNumber evidence="5">2.3.3.10</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">3-hydroxy-3-methylglutaryl coenzyme A synthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">HMGCS1</name>
        <name evidence="8" type="ORF">A0J61_09159</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Catalyzes the condensation of acetyl-CoA with acetoacetyl-CoA to form HMG-CoA.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>acetoacetyl-CoA + acetyl-CoA + H2O = (3S)-3-hydroxy-3-methylglutaryl-CoA + CoA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:10188"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:43074"/>
            <dbReference type="ChEBI" id="CHEBI:57286"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="EC" id="2.3.3.10"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the thiolase-like superfamily. HMG-CoA synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.3.10" evidence="5"/>
    <dbReference type="EMBL" id="LUGH01000786">
        <property type="protein sequence ID" value="OBZ82789.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N2D9"/>
    <dbReference type="FunCoup" id="A0A1C7N2D9">
        <property type="interactions" value="276"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N2D9"/>
    <dbReference type="InParanoid" id="A0A1C7N2D9"/>
    <dbReference type="OrthoDB" id="1269963at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004421">
        <property type="term" value="F:hydroxymethylglutaryl-CoA synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006084">
        <property type="term" value="P:acetyl-CoA metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006696">
        <property type="term" value="P:ergosterol biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010142">
        <property type="term" value="P:farnesyl diphosphate biosynthetic process, mevalonate pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd00827">
        <property type="entry name" value="init_cond_enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.47.10:FF:000008">
        <property type="entry name" value="3-hydroxy-3-methylglutaryl coenzyme A synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013746">
        <property type="entry name" value="HMG_CoA_synt_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013528">
        <property type="entry name" value="HMG_CoA_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010122">
        <property type="entry name" value="HMG_CoA_synthase_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01833">
        <property type="entry name" value="HMG-CoA-S_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43323">
        <property type="entry name" value="3-HYDROXY-3-METHYLGLUTARYL COENZYME A SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43323:SF2">
        <property type="entry name" value="HYDROXYMETHYLGLUTARYL-COA SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08540">
        <property type="entry name" value="HMG_CoA_synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01154">
        <property type="entry name" value="HMG_CoA_synt_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="Thiolase-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Hydroxymethylglutaryl-coenzyme A synthase N-terminal" evidence="6">
        <location>
            <begin position="9"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="domain" description="Hydroxymethylglutaryl-coenzyme A synthase C-terminal" evidence="7">
        <location>
            <begin position="183"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor/acceptor" evidence="3">
        <location>
            <position position="91"/>
        </location>
    </feature>
    <feature type="active site" description="Acyl-thioester intermediate" evidence="3">
        <location>
            <position position="125"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor/acceptor" evidence="3">
        <location>
            <position position="256"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="217"/>
        </location>
        <ligand>
            <name>CoA</name>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="261"/>
        </location>
        <ligand>
            <name>CoA</name>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="265"/>
        </location>
        <ligand>
            <name>CoA</name>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR610122-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR610122-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU364071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01154"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF08540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OBZ82789.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="452" mass="50545" checksum="07888F97168B4705" modified="2016-11-30" version="1">MTASNYSHYPENVGVLAMEMYFPKRCVVQSDMEAFDGVSAGKYTIGLGQEKMAFIDDREDIQSICLTAVQNLMEKYNISYNDIGRLEVGTETIIDKSKAVKTCLMTLFSEHGNTEIEGIDTTNACYGGFAAFSNAVNWIESSSWDGRFAIVVAGDLALYASGAARPTSGAGVVAMLIGKDAPIVVERGLRSTHMEHAYDFYKPDMHSEYPVVDGKFSNVCYLRAFDSCYRRYMARLAKLENKEKPSMDDIDYVVCHSPYAKLVNKSFARASYNDFLLDKDNEKYATLKTFEELSYADSLESKDLEKALMGLTKAAYTQKVGPAAFAPKQIGNMYTAAVWAGLASLVSEVDSETLQDKRIMLYSYGSGLASSMISFRVRGNTSDIQSKLSLRERLDARVHSKPEEFAEAMKMREHTHNACNFTPSGSLDNIATGAYYVEKIDDKWRRFYKRKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N2F1</accession>
    <name>A0A1C7N2F1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 11">Nucleoside diphosphate kinase</fullName>
            <ecNumber evidence="3 11">2.7.4.6</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">swoH</name>
        <name evidence="13" type="ORF">A0J61_10416</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="15 11">
            <text>a 2'-deoxyribonucleoside 5'-diphosphate + ATP = a 2'-deoxyribonucleoside 5'-triphosphate + ADP</text>
            <dbReference type="Rhea" id="RHEA:44640"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61560"/>
            <dbReference type="ChEBI" id="CHEBI:73316"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.4.6"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 9 10">Belongs to the NDK family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.4.6" evidence="3 11"/>
    <dbReference type="EMBL" id="LUGH01001162">
        <property type="protein sequence ID" value="OBZ81534.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N2F1"/>
    <dbReference type="FunCoup" id="A0A1C7N2F1">
        <property type="interactions" value="517"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N2F1"/>
    <dbReference type="InParanoid" id="A0A1C7N2F1"/>
    <dbReference type="OrthoDB" id="2162449at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004550">
        <property type="term" value="F:nucleoside diphosphate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006241">
        <property type="term" value="P:CTP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006183">
        <property type="term" value="P:GTP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006228">
        <property type="term" value="P:UTP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04413">
        <property type="entry name" value="NDPk_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.141:FF:000002">
        <property type="entry name" value="Nucleoside diphosphate kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.141">
        <property type="entry name" value="Nucleoside diphosphate kinase-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00451">
        <property type="entry name" value="NDP_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034907">
        <property type="entry name" value="NDK-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036850">
        <property type="entry name" value="NDK-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001564">
        <property type="entry name" value="Nucleoside_diP_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023005">
        <property type="entry name" value="Nucleoside_diP_kinase_AS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF001908">
        <property type="entry name" value="PRK00668.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11349">
        <property type="entry name" value="NUCLEOSIDE DIPHOSPHATE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00334">
        <property type="entry name" value="NDK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01243">
        <property type="entry name" value="NUCDPKINASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00562">
        <property type="entry name" value="NDK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54919">
        <property type="entry name" value="Nucleoside diphosphate kinase, NDK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00469">
        <property type="entry name" value="NDPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51374">
        <property type="entry name" value="NDPK_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7 11 13" id="KW-0418">Kinase</keyword>
    <keyword evidence="6 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 11" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Nucleoside diphosphate kinase-like" evidence="12">
        <location>
            <begin position="1"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="active site" description="Pros-phosphohistidine intermediate" evidence="9">
        <location>
            <position position="115"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="9"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="57"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="85"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="91"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="102"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="112"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008142"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00017632"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00706"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU004011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU004013"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM00562"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="OBZ81534.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="151" mass="16852" checksum="1F1E2B41CD9140B3" modified="2016-11-30" version="1">MERTYIMVKPDGVERGIVGEIIKRFENKGYQLTALELIHPTAELLEEHYGDLKGKPFFPSLIEYMTSGPVVGMVWTGKDAVKTGRRMLGETNPLASAPGTIRGDFCIEVGRNICHGSDSVENAEKEIALWFPRGVKTVARSHSIHSLFYEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N3A9</accession>
    <name>A0A1C7N3A9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Cytochrome c oxidase assembly protein COX11, mitochondrial</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">COX11</name>
        <name evidence="6" type="ORF">A0J61_08449</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion inner membrane</location>
            <topology evidence="2">Single-pass membrane protein</topology>
            <orientation evidence="2">Intermembrane side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000651">
        <property type="protein sequence ID" value="OBZ83507.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N3A9"/>
    <dbReference type="STRING" id="101091.A0A1C7N3A9"/>
    <dbReference type="InParanoid" id="A0A1C7N3A9"/>
    <dbReference type="OrthoDB" id="1704689at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005758">
        <property type="term" value="C:mitochondrial intermembrane space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005761">
        <property type="term" value="C:mitochondrial ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005507">
        <property type="term" value="F:copper ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009060">
        <property type="term" value="P:aerobic respiration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045454">
        <property type="term" value="P:cell redox homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033617">
        <property type="term" value="P:mitochondrial respiratory chain complex IV assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.370.10:FF:000001">
        <property type="entry name" value="COX11 cytochrome c oxidase assembly homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.370.10">
        <property type="entry name" value="Ctag/Cox11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00155">
        <property type="entry name" value="CtaG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023471">
        <property type="entry name" value="CtaG/Cox11_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007533">
        <property type="entry name" value="Cyt_c_oxidase_assmbl_CtaG"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003465">
        <property type="entry name" value="PRK05089.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21320:SF3">
        <property type="entry name" value="CYTOCHROME C OXIDASE ASSEMBLY PROTEIN COX11, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21320">
        <property type="entry name" value="CYTOCHROME C OXIDASE ASSEMBLY PROTEIN COX11-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04442">
        <property type="entry name" value="CtaG_Cox11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005413">
        <property type="entry name" value="COX11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110111">
        <property type="entry name" value="Ctag/Cox11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004243"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OBZ83507.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="223" mass="25455" checksum="5D31950ED9CD1A0E" modified="2016-11-30" version="1">MFKTTLRSLYTTRTIRQCHRIPQGHRFYSSRPNYESNSSAGMYTASVFISMLGISYAAVPLYRLFCASTGYSGTPVVDNARFGPERLVPQEQSRRIRVTFESNTSDSLPWTFKPEMREVYVVPGETALTFYKAKSKAKEDVIGIATYNVTPYRAGSYFNKIQCFCFEEQKLKPGEDVDMPVFFFIDPDFLEDPLMKDVNTITLSYTFFNSKHAQGLAPVQPLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N3E0</accession>
    <name>A0A1C7N3E0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">60S acidic ribosomal protein P2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">RLA2</name>
        <name evidence="7" type="ORF">A0J61_08359</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the eukaryotic ribosomal protein P1/P2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000635">
        <property type="protein sequence ID" value="OBZ83591.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N3E0"/>
    <dbReference type="STRING" id="101091.A0A1C7N3E0"/>
    <dbReference type="InParanoid" id="A0A1C7N3E0"/>
    <dbReference type="OrthoDB" id="1227494at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022625">
        <property type="term" value="C:cytosolic large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002182">
        <property type="term" value="P:cytoplasmic translational elongation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05833">
        <property type="entry name" value="Ribosomal_P2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.1410:FF:000002">
        <property type="entry name" value="60S acidic ribosomal protein P2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.1410">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01478">
        <property type="entry name" value="Ribosomal_L12_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038716">
        <property type="entry name" value="P1/P2_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027534">
        <property type="entry name" value="Ribosomal_P1/P2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001859">
        <property type="entry name" value="Ribosomal_P1/P2_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044076">
        <property type="entry name" value="Ribosomal_P2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21141">
        <property type="entry name" value="60S ACIDIC RIBOSOMAL PROTEIN FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21141:SF5">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN P2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00428">
        <property type="entry name" value="Ribosomal_60s"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00456">
        <property type="entry name" value="RIBOSOMALP2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 7" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008889464" evidence="6">
        <location>
            <begin position="17"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="79"/>
            <end position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005436"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OBZ83591.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="109" mass="10687" checksum="5FE806BFA82C0438" modified="2016-11-30" version="1">MKHLAAYLLLVAGGNAHPTADDLKKVMGSVGVEVDESRVSALLKAMEGKTAAEAIAEGSSKLASVSAGPVAAAGGAAAAGAAGADAPAEEAKAEEKEESDDDMGFGLFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N431</accession>
    <name>A0A1C7N431_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">anthranilate synthase</fullName>
            <ecNumber evidence="3">4.1.3.27</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">trp3</name>
        <name evidence="10" type="ORF">A0J61_09875</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Amino-acid biosynthesis; L-tryptophan biosynthesis; L-tryptophan from chorismate: step 1/5.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the anthranilate synthase component I family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.1.3.27" evidence="3"/>
    <dbReference type="EMBL" id="LUGH01000961">
        <property type="protein sequence ID" value="OBZ82074.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N431"/>
    <dbReference type="FunCoup" id="A0A1C7N431">
        <property type="interactions" value="154"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N431"/>
    <dbReference type="InParanoid" id="A0A1C7N431"/>
    <dbReference type="OrthoDB" id="1865897at2759"/>
    <dbReference type="UniPathway" id="UPA00035">
        <property type="reaction ID" value="UER00040"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005950">
        <property type="term" value="C:anthranilate synthase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004049">
        <property type="term" value="F:anthranilate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006541">
        <property type="term" value="P:glutamine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000162">
        <property type="term" value="P:L-tryptophan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.120.10">
        <property type="entry name" value="Anthranilate synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005801">
        <property type="entry name" value="ADC_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019999">
        <property type="entry name" value="Anth_synth_I-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006805">
        <property type="entry name" value="Anth_synth_I_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005256">
        <property type="entry name" value="Anth_synth_I_PabB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015890">
        <property type="entry name" value="Chorismate_C"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00564">
        <property type="entry name" value="trpE_most"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11236">
        <property type="entry name" value="AMINOBENZOATE/ANTHRANILATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11236:SF9">
        <property type="entry name" value="ANTHRANILATE SYNTHASE COMPONENT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04715">
        <property type="entry name" value="Anth_synt_I_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00425">
        <property type="entry name" value="Chorismate_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00095">
        <property type="entry name" value="ANTSNTHASEI"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56322">
        <property type="entry name" value="ADC synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="6" id="KW-0057">Aromatic amino acid biosynthesis</keyword>
    <keyword evidence="7" id="KW-0456">Lyase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0822">Tryptophan biosynthesis</keyword>
    <feature type="domain" description="Anthranilate synthase component I N-terminal" evidence="9">
        <location>
            <begin position="34"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="domain" description="Chorismate-utilising enzyme C-terminal" evidence="8">
        <location>
            <begin position="221"/>
            <end position="474"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004873"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009562"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022822"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF04715"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OBZ82074.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="497" mass="55924" checksum="B5CD5B2AA82DA2C8" modified="2016-11-30" version="1">MSLQLKPTLEEVQEIVSSGKGNTIPIYAELEADFLTPVSAYLKVADRCDYSFLFESVEGGENISRYSFIGSDPYKLIRVGSDEKINGDPLIPIQRELEHIRYVKIPGLPSFTGGAVGYVGFDCYQYFEPSIQGELEDPLGIPDAIFMMCDTLVIFDRVRQIVNVVSHFRSDVTEPEEVAREYRKAAEEIETTLCLLNQERIPPVPQGPITLGKQAVSNVGKEGYMGFVSQLKHHIKEGDIFQAVPSQRLARPTDLHPFNVYRHLRSLNPSPYMFYMNLKEFTIVGASPEMLTKVQDGKAYTHPIAGTRKRGKTAEEDQALADDLLKDPKEIAEHVMLVDLGRNDINRICRPESVKVDRLMQIEYYSHVMHIVSNVSGQLRDNQTPFDAFRAIFPAGTVSGAPKIRAVELIRGLEKQKRGIYAGAVGHFDYSGDLDTCIAIRTMVFKDQVAYLQAGGGIVYDSVEEDEYQETMNKMGSNLATIDQCERKLYQQQQQQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N4B5</accession>
    <name>A0A1C7N4B5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_08485</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000658">
        <property type="protein sequence ID" value="OBZ83469.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N4B5"/>
    <dbReference type="STRING" id="101091.A0A1C7N4B5"/>
    <dbReference type="InParanoid" id="A0A1C7N4B5"/>
    <dbReference type="OrthoDB" id="2504266at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="90"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="287"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="567"/>
            <end position="606"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="91"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="112"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="139"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="159"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="189"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="212"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="287"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="299"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="337"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="372"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="405"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="569"/>
            <end position="578"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="596"/>
            <end position="606"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ83469.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="606" mass="69035" checksum="A3C2EB2C324F9C05" modified="2016-11-30" version="1">MSDKATEVIRYTKEAMISLHDSPLVQKPENMPSLLTWFGEDPESPASKSILNGYVITRTSSEKSIVLGPTKTNFASSLYGGLKNQNEHYHTTSTKTQPMSNSRYNHHQNHARQMDDRTNTTSIREYRSPRGPSFMNDRGFSHNRQDKSTDNRKFMNSPPHKRNNNNNNHHHERNNNSNGKLHHHRNNRHHELEGSERVPEWMDYTPDEETIGEVREDIKKEKELETHDLEAWKSSMKQKDNPTTTAIEAPLSSLSLEPSQDPLLFFDESSEPRREQKGGSRFAKFFAKREEPHQETEETNTPQPRSISLNDLFQQPSPKKRQEDLTEPHIPQAGRIYSEEDILKSLGAKKETTSPDEQLNEEGAMGFNRVLQILSQPKPSLSSSSHSSPIPEEHASPSPKLVHENTGSESSSRIANRFGNNNLPTSVLRQMSARSSSEGKSPLLQNTKSTPTSTKPVQPVFNHPPPPHMPPLPMPPQQFFAMQQNGPYSPGHPMMDHRAFEQLMQFNNDPRMPPPHPHHLRNGNNGDFLPPHMMMGPPPPPLPPGQRPMMTPPQFNQQLPLHMQRFPLQQQQQQQQQQMTSMLPHLLANGIPPQLANKSQGWEQRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N4F4</accession>
    <name>A0A1C7N4F4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_07927</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000568">
        <property type="protein sequence ID" value="OBZ84015.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N4F4"/>
    <dbReference type="STRING" id="101091.A0A1C7N4F4"/>
    <dbReference type="InParanoid" id="A0A1C7N4F4"/>
    <dbReference type="OrthoDB" id="10256309at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="81"/>
            <end position="175"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ84015.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="306" mass="35587" checksum="A014C072A26574D1" modified="2016-11-30" version="1">MSTQSIDQLALAISNISHVEQPYMNNLLVIKKLEIAKEPIDIEHREALSKVVMWETEVLNLDSWTVQWLLAKLTCSVQAEKDRTRKGLEKAKSLVEETEKKVQVETDKIHEVEVQNEKYAVDHRELQKYREEISSLLDKALQQETSKTQECKDKIDETKKKAEEQLENVKKLDKVKEYIKNADIALLEAILELRSSNVKESLMGNGKVYFPELAYECLKKAREEYPDLPGFSSPTEYVNEADNTGAYYSPMQKYLWDVRKKLAELIIWCDREVISLLEKETQLQIELGKHTDNYNYERRDALKASV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N4Q7</accession>
    <name>A0A1C7N4Q7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">UDP-N-acetylglucosamine transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">Slc35a3</name>
        <name evidence="7" type="ORF">A0J61_07836</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000554">
        <property type="protein sequence ID" value="OBZ84112.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N4Q7"/>
    <dbReference type="InParanoid" id="A0A1C7N4Q7"/>
    <dbReference type="OrthoDB" id="408493at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015165">
        <property type="term" value="F:pyrimidine nucleotide-sugar transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd09274">
        <property type="entry name" value="RNase_HI_RT_Ty3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043502">
        <property type="entry name" value="DNA/RNA_pol_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037185">
        <property type="entry name" value="EmrE-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007271">
        <property type="entry name" value="Nuc_sug_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041577">
        <property type="entry name" value="RT_RNaseH_2"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00803">
        <property type="entry name" value="nst"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10231">
        <property type="entry name" value="NUCLEOTIDE-SUGAR TRANSMEMBRANE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04142">
        <property type="entry name" value="Nuc_sug_transp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17919">
        <property type="entry name" value="RT_RNaseH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56672">
        <property type="entry name" value="DNA/RNA polymerases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103481">
        <property type="entry name" value="Multidrug resistance efflux transporter EmrE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="326"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="429"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="467"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="499"/>
            <end position="520"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="536"/>
            <end position="556"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="563"/>
            <end position="583"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="589"/>
            <end position="610"/>
        </location>
    </feature>
    <feature type="domain" description="Reverse transcriptase/retrotransposon-derived protein RNase H-like" evidence="6">
        <location>
            <begin position="59"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="unsure residue" description="D or N" evidence="7">
        <location>
            <position position="157"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF17919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OBZ84112.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="620" mass="70185" checksum="1D075934CE012006" modified="2016-11-30" version="1" fragment="single">KIDLSRLSNINNWKIPQTAAQVRSLMKVISHLRDFCPMLSKVVAPIDQLRTDADVKTKWTDLHTERLNSIKKILQSGLVLHQVDLSKKIYLECDASLYGLGCALSQRDELGRTKYIAFISRSLSPXERSWSTNRRETEALCFGXERFRPLLWGRSKDXFEXRVDHMALTFLHTSKCLNPTLQSRLEIIGDFDFTITHIKGLENTLPDSLSRLYPPIPEDQALEGKDDKQLKRLKRMILTKRADLIQKKDKYTHTRRIYLKLTSVLEHLINQQLQQSNFQIIVIDNNNVASVQLKQLSLVVLVVQNSTLVLMMRYSRIVQKPGQQLYIASTAVFLAEVLKIVACLIVLRYQIGSWDRFRYAIQREIIGRPTETLKMLIPSGLYALQNNLLYVALSNLEAASFQVTYQMKIMSTAIFSVVLLGKSLSRDKWFALFLLMIGVTLVQSQSMSASSSSSVTDEVILAPQNPLIGFLAVITSCISSGFAGCYFEKILKTSETSMWIRNIQLGISGTLFSMLGMLIYDIQPIMNDGMLQGYDWLTWVVVANQALGGLLVAIVVKYADNILKGFATSLSIIVSGVISIYLFHFQPSSVFIVGAFIVMLSSYLYGIDFLKRFQTRAKPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-06-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N5F5</accession>
    <name>A0A1C7N5F5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_08062</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000588">
        <property type="protein sequence ID" value="OBZ83886.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N5F5"/>
    <dbReference type="InParanoid" id="A0A1C7N5F5"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ83886.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="110" mass="12425" checksum="FD423279EBA87918" modified="2016-11-30" version="1">MPTKFQAFRSSLIDLLSSFNRSTTEFSGNVAKQSFDPTSFLHLKISSLSCKSRLLRSLFFKLENSGKKKTNGRPLYLSTQFAPLLARETSLLSGVSLILIWFISRMEKLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N5G2</accession>
    <name>A0A1C7N5G2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Guanine nucleotide-binding protein alpha-3 subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">FIL1</name>
        <name evidence="12" type="ORF">A0J61_07723</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000538">
        <property type="protein sequence ID" value="OBZ84228.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N5G2"/>
    <dbReference type="FunCoup" id="A0A1C7N5G2">
        <property type="interactions" value="171"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N5G2"/>
    <dbReference type="InParanoid" id="A0A1C7N5G2"/>
    <dbReference type="OrthoDB" id="5817230at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005834">
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        <property type="entry name" value="P-loop_NTPase"/>
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        <property type="entry name" value="GTP-BINDING PROTEIN ALPHA SUBUNIT"/>
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        <property type="entry name" value="GUANINE NUCLEOTIDE-BINDING PROTEIN ALPHA-2 SUBUNIT"/>
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        <property type="entry name" value="G-alpha"/>
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        <property type="entry name" value="GPROTEINA"/>
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        <property type="entry name" value="GPROTEINAFNG"/>
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        <property type="entry name" value="G_ALPHA"/>
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    <proteinExistence type="predicted"/>
    <keyword evidence="5 9" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="8" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="4 10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="2 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1" id="KW-0519">Myristate</keyword>
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    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0807">Transducer</keyword>
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        <location>
            <begin position="1"/>
            <end position="21"/>
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            <begin position="44"/>
            <end position="49"/>
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        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
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        <location>
            <position position="48"/>
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        <ligand>
            <name>Mg(2+)</name>
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            <begin position="153"/>
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            <begin position="178"/>
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        <ligand>
            <name>GTP</name>
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            <position position="184"/>
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        <ligand>
            <name>Mg(2+)</name>
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            <begin position="203"/>
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            <dbReference type="ARBA" id="ARBA00022723"/>
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    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
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    </evidence>
    <sequence length="355" mass="41012" checksum="EB95CD91D2B090F8" modified="2016-11-30" version="1">MGLCHSSEEDNQEHQRSNEIDKLIEKERNNREKECKILLLGSGESGKSTILKQMKIINLNGYSQEELFTWRTTVYRNIVESTQTIVQAFVDSGKSFQTPQLNDYVERILAYRISGNPKSQLSPEIVAFIRLLWKDPSVKDSIEDVEKRYYIMDSAAYFFDSIDRIGQASYLPDEQDVLRARLKTTGITEIEFQLGSLMIHMFDVGGQRSERKKWIHCFESVTSIIFCVALSEYDQVLLEESSQNRMMESLALFESVVNSRWFIHSSIMLFLNKVDIFKAKLSASPLDRYFPDYGGGHDANKAAKYILWRFLQCNRNKLNIYPHLTQATDTSNIRFVFAAVRETLLQNALRDSGML</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N5K3</accession>
    <name>A0A1C7N5K3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="15">Kinesin-like protein KIF21A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="15" type="primary">Kif21a_1</name>
        <name evidence="15" type="ORF">A0J61_07680</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="11">Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000533">
        <property type="protein sequence ID" value="OBZ84268.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N5K3"/>
    <dbReference type="FunCoup" id="A0A1C7N5K3">
        <property type="interactions" value="331"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N5K3"/>
    <dbReference type="InParanoid" id="A0A1C7N5K3"/>
    <dbReference type="OrthoDB" id="3176171at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005875">
        <property type="term" value="C:microtubule associated complex"/>
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        <property type="project" value="TreeGrafter"/>
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        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008017">
        <property type="term" value="F:microtubule binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003777">
        <property type="term" value="F:microtubule motor activity"/>
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        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007018">
        <property type="term" value="P:microtubule-based movement"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007052">
        <property type="term" value="P:mitotic spindle organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051231">
        <property type="term" value="P:spindle elongation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01372">
        <property type="entry name" value="KISc_KIF4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.850.10:FF:000011">
        <property type="entry name" value="Kinesin family member 21A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.850.10">
        <property type="entry name" value="Kinesin motor domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027640">
        <property type="entry name" value="Kinesin-like_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019821">
        <property type="entry name" value="Kinesin_motor_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001752">
        <property type="entry name" value="Kinesin_motor_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036961">
        <property type="entry name" value="Kinesin_motor_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47969">
        <property type="entry name" value="CHROMOSOME-ASSOCIATED KINESIN KIF4A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47969:SF15">
        <property type="entry name" value="CHROMOSOME-ASSOCIATED KINESIN KIF4A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00225">
        <property type="entry name" value="Kinesin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00380">
        <property type="entry name" value="KINESINHEAVY"/>
    </dbReference>
    <dbReference type="SMART" id="SM00129">
        <property type="entry name" value="KISc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00411">
        <property type="entry name" value="KINESIN_MOTOR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50067">
        <property type="entry name" value="KINESIN_MOTOR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8 12" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="10" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="4" id="KW-0493">Microtubule</keyword>
    <keyword evidence="9 11" id="KW-0505">Motor protein</keyword>
    <keyword evidence="6 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="Kinesin motor" evidence="14">
        <location>
            <begin position="4"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="516"/>
            <end position="553"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="12">
        <location>
            <begin position="398"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="12">
        <location>
            <begin position="567"/>
            <end position="594"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="12">
        <location>
            <begin position="651"/>
            <end position="806"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="13">
        <location>
            <begin position="533"/>
            <end position="552"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="84"/>
            <end position="91"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="non-terminal residue" evidence="15">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="15">
        <location>
            <position position="1074"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00283"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50067"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="OBZ84268.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="1074" mass="122272" checksum="57A1985C0E28A87A" modified="2016-11-30" version="1" fragment="single">NSSSVRVALRIRPLTEQEKQHHQNNVISFIPDSQQQINVNNERSFTFDYVYPPSVNQHDVYATCVVPLLDKFVEGYNATILAYGQTGSGKTYSMGIGLDNVMKMSINDHGIVPRFIHALFNHLHAKQKSPNYSFQLSVSFLELHNEDLVDLLCPAKQRDGLNLTIREDSHGNICWAGVREETVTTANELLEILQKGSIARTTASTDMNNTSSRSHAIFSVMLKQSVLQQDVTDDESTLHSDMELSPTPLEKKLISKFHFVDLAGSERLKRTNAVGDRAKEGISINTGLLALGNVISALGDESRRVSHIPYRDSKLTRLLQDSLGGNSQTLMLACASPASSNLTETLNTLKYANRARNIRNRVKINQQQQQDISNKKEERLKAVITRLKQELRSTDDFLRAVNDEMDSLKMEVGSLQQTLSQTVNELTHIKSERDSFKRQLMAATGQEDVQSHDDQMAREYINTIESLKLELYQTQQRLINQKQQKNLSLEINPIDSSPTLVGSPCQSPYLELKPQVIPDNIFQSSTPSEKTDKKRKKHRANSKRSKTTRRKAAIPSVNNSITKPTLNLSLNEAKQALQNELELAQSANIALNEMAVKYEHTANHSPNANKHRRHTLDSDSFKVLAQFDSMNEAKRCIQKLTLVIENKHQMIRQFEKSEKQQTDQIKQLSRTVNDLASKKATSIQNLKKELNDLRTQYEARLKKQQGEQVALRRKHLQLIRSSDRTRHQHESKIEQCNRTIEKLGHEKKKLLKRIKVEADRAKEKASEADREMKKMKRQEAQSVTIKRRMERELALQKSACKRATEEIVALSGHMKQIAAILKKVMASTTVLSQRNLLAKAIACASVRGYLIKQNAVKKAGGKFQVTTLQQNVYQKKKFIHKALYLYVKGQYATHPLIQELVQKRTRLLEEQKELLAERQMVLMEENTMDSTEPQYMDERIELITMELDTLDQHIYHLTTSSEAPLLQHLDDDSDINWTDDQMDQQVAYELALSLIRSLEPDEARLISEALLQDVIALKADQITHTNSLHHFNSVMRVFQSALVNIKRLTNEPTIMTDTIKGPSCVQYGLVLPQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N666</accession>
    <name>A0A1C7N666_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Vacuolar amino acid transporter 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">avt3_4</name>
        <name evidence="8" type="ORF">A0J61_07349</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the amino acid/polyamine transporter 2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000490">
        <property type="protein sequence ID" value="OBZ84600.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N666"/>
    <dbReference type="STRING" id="101091.A0A1C7N666"/>
    <dbReference type="InParanoid" id="A0A1C7N666"/>
    <dbReference type="OrthoDB" id="1684102at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005774">
        <property type="term" value="C:vacuolar membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015179">
        <property type="term" value="F:L-amino acid transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1740.10">
        <property type="entry name" value="Amino acid/polyamine transporter I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013057">
        <property type="entry name" value="AA_transpt_TM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22950">
        <property type="entry name" value="AMINO ACID TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22950:SF666">
        <property type="entry name" value="VACUOLAR AMINO ACID TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01490">
        <property type="entry name" value="Aa_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006060">
        <property type="entry name" value="AA_transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="71"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="97"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="139"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="183"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="206"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="249"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="282"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="324"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="371"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="396"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="428"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="domain" description="Amino acid transporter transmembrane" evidence="7">
        <location>
            <begin position="65"/>
            <end position="446"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008066"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OBZ84600.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="454" mass="50036" checksum="FAA2712E5E572502" modified="2016-11-30" version="1">MSNTDSVRPPISQEKSGYSVRQVNNSDKHEVAMPHQEDVYIQHDKEASSIITYDEEQIEHAPEGTAGPLKALYMLLKSFIGTGVIFLPGSFVNGGLVVSTVLMVVIAIICTYSFHALVQSQRTVGGSYGNVAQVLYGRWMRYFIDFSLCLSQMGFVSSYFIFISSNIGVAVRSLNDGYEPFDSKYYIWLILLIIAPFTWARKLNKLAPLVALAEIFIAFGLICVVYFSSREISQSGLGPGIVMANSKDFALMIGTAVFAFEGIGMVVPVVEAMKEPEKFPRVLNLGMIISTVVFTFIGLIGYLAYGENTASNVVTNFPAEPLSVAVQILYAVAIISSAPFMLYPAVTITERGLYGPNQSGRISWRYKWMKNFTRSLIPIVCACVSFGVGASNLDKFVSLVGSVACMPLCFIYPGLFHYKTSPGKYTRPLDIVLVIFGIAILIYTLYINVNSWIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N681</accession>
    <name>A0A1C7N681_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">WD repeat-containing protein 89</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">Wdr89</name>
        <name evidence="4" type="ORF">A0J61_07343</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000489">
        <property type="protein sequence ID" value="OBZ84610.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N681"/>
    <dbReference type="FunCoup" id="A0A1C7N681">
        <property type="interactions" value="334"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N681"/>
    <dbReference type="InParanoid" id="A0A1C7N681"/>
    <dbReference type="OrthoDB" id="25131at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039328">
        <property type="entry name" value="WDR89"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22889">
        <property type="entry name" value="WD REPEAT-CONTAINING PROTEIN 89"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22889:SF0">
        <property type="entry name" value="WD REPEAT-CONTAINING PROTEIN 89"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="65"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="299"/>
            <end position="334"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OBZ84610.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="334" mass="37522" checksum="8170CB99F9356E41" modified="2016-11-30" version="1">MSSNIQVETCTDLLAPFQLIKGIDLGYEDAYVFDVTANSQYAITSASDNFIRLYDLSTLQLSLTIPAHSNRISKMKLKSDQYLFTSSEDGTLKRWDLRTPQNPIQQFQYNKPLTAFDINCNDTMAILGTEFSTETQSADLAFFDTRNTNLLHAFTESHGDDVTEIQCHPSLPAQFLSCSTDGIINSYDVTEFDEEEAMTSAINSGSSVNKIGYFGPNAEYLYCLTHIETFSLHTLEGDLICDYGDIRTIQLTEIDYAIDCSYDPITQRFYLVTGNNSGTVDFFHVNIGQLQHCQQLKMPNSHSDVVRSLYWNHPTQSVLTGGEDGRLCAWQGQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N6A8</accession>
    <name>A0A1C7N6A8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">ATP-dependent (S)-NAD(P)H-hydrate dehydratase</fullName>
            <ecNumber evidence="8">4.2.1.93</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">ATP-dependent NAD(P)HX dehydratase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">A0J61_07801</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ATP, which is converted to ADP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>(6S)-NADHX + ATP = ADP + phosphate + NADH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:19017"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:64074"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="4.2.1.93"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7 8">
            <text>(6S)-NADPHX + ATP = ADP + phosphate + NADPH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:32231"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:64076"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="4.2.1.93"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the NnrD/CARKD family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.93" evidence="8"/>
    <dbReference type="EMBL" id="LUGH01000549">
        <property type="protein sequence ID" value="OBZ84146.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N6A8"/>
    <dbReference type="FunCoup" id="A0A1C7N6A8">
        <property type="interactions" value="18"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N6A8"/>
    <dbReference type="InParanoid" id="A0A1C7N6A8"/>
    <dbReference type="OrthoDB" id="8110916at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047453">
        <property type="term" value="F:ATP-dependent NAD(P)H-hydrate dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0110051">
        <property type="term" value="P:metabolite repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046496">
        <property type="term" value="P:nicotinamide nucleotide metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01171">
        <property type="entry name" value="YXKO-related"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.1190.20:FF:000023">
        <property type="entry name" value="ATP-dependent (S)-NAD(P)H-hydrate dehydratase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1190.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01965">
        <property type="entry name" value="NADHX_dehydratase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000631">
        <property type="entry name" value="CARKD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029056">
        <property type="entry name" value="Ribokinase-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00196">
        <property type="entry name" value="yjeF_cterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12592:SF0">
        <property type="entry name" value="ATP-DEPENDENT (S)-NAD(P)H-HYDRATE DEHYDRATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12592">
        <property type="entry name" value="ATP-DEPENDENT (S)-NAD(P)H-HYDRATE DEHYDRATASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01256">
        <property type="entry name" value="Carb_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53613">
        <property type="entry name" value="Ribokinase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51383">
        <property type="entry name" value="YJEF_C_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 8" id="KW-0456">Lyase</keyword>
    <keyword evidence="5 8" id="KW-0520">NAD</keyword>
    <keyword evidence="4" id="KW-0521">NADP</keyword>
    <keyword evidence="2 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="1 8" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="YjeF C-terminal" evidence="9">
        <location>
            <begin position="6"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="116"/>
        </location>
        <ligand>
            <name>(6S)-NADPHX</name>
            <dbReference type="ChEBI" id="CHEBI:64076"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="169"/>
            <end position="175"/>
        </location>
        <ligand>
            <name>(6S)-NADPHX</name>
            <dbReference type="ChEBI" id="CHEBI:64076"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="209"/>
            <end position="213"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="228"/>
            <end position="237"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="238"/>
        </location>
        <ligand>
            <name>(6S)-NADPHX</name>
            <dbReference type="ChEBI" id="CHEBI:64076"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047472"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51383"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OBZ84146.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="316" mass="34577" checksum="F9101E496B374030" modified="2016-11-30" version="1">MPKLPDISKVRQLVPPLSGRMHKGQAGRIGVVGGSEDYTGAPFFSGIASMKVGVDLCHIFCEPGAGTVIKGYSPDLIVHPYMRTKEKLEPELSVDKIVDRVSSVFSRLHVLVVGPGLSRDEVMQETTRQLILRAREQDMAIVVDADGLYLVQQHPETVKDYKKAVLTPNVVEFKRLCDKMGVDIDKEDSHESAAKKLAKSFGGLTVVQKGSEDCITNGDEVLKCDAEGGLKRMGGQGDILSGAIAAFLAWGKAYEDGVWSHSNEIASKDIAMFASWGACWISRTSSKLAYEKHGRSVLTSHMLEEIGTSYDRFMKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N6J1</accession>
    <name>A0A1C7N6J1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Palmitoyltransferase</fullName>
            <ecNumber evidence="12">2.3.1.225</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="primary">AKR1</name>
        <name evidence="15" type="ORF">A0J61_07330</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>L-cysteinyl-[protein] + hexadecanoyl-CoA = S-hexadecanoyl-L-cysteinyl-[protein] + CoA</text>
            <dbReference type="Rhea" id="RHEA:36683"/>
            <dbReference type="Rhea" id="RHEA-COMP:10131"/>
            <dbReference type="Rhea" id="RHEA-COMP:11032"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57379"/>
            <dbReference type="ChEBI" id="CHEBI:74151"/>
            <dbReference type="EC" id="2.3.1.225"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="12">The DHHC domain is required for palmitoyltransferase activity.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the DHHC palmitoyltransferase family. AKR/ZDHHC17 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.225" evidence="12"/>
    <dbReference type="EMBL" id="LUGH01000488">
        <property type="protein sequence ID" value="OBZ84618.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N6J1"/>
    <dbReference type="FunCoup" id="A0A1C7N6J1">
        <property type="interactions" value="331"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N6J1"/>
    <dbReference type="InParanoid" id="A0A1C7N6J1"/>
    <dbReference type="OrthoDB" id="6781668at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019706">
        <property type="term" value="F:protein-cysteine S-palmitoyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001594">
        <property type="entry name" value="Palmitoyltrfase_DHHC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24161">
        <property type="entry name" value="ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24161:SF85">
        <property type="entry name" value="PALMITOYLTRANSFERASE HIP14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13637">
        <property type="entry name" value="Ank_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01529">
        <property type="entry name" value="DHHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01415">
        <property type="entry name" value="ANKYRIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50216">
        <property type="entry name" value="DHHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="6 11" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="9" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="7 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0564">Palmitate</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="12 15" id="KW-0808">Transferase</keyword>
    <keyword evidence="3 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 12" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="309"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="335"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="366"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="394"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="494"/>
            <end position="518"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="550"/>
            <end position="570"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="11">
        <location>
            <begin position="86"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="11">
        <location>
            <begin position="120"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="11">
        <location>
            <begin position="153"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="11">
        <location>
            <begin position="187"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="11">
        <location>
            <begin position="220"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="domain" description="Palmitoyltransferase DHHC" evidence="14">
        <location>
            <begin position="448"/>
            <end position="583"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="20"/>
            <end position="35"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00048048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU079119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF01529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="OBZ84618.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="710" mass="79130" checksum="99D898292438CD13" modified="2016-11-30" version="1">MTAEDHSEDKVPLLEESVVSEPTTPFSVLPKQPTTTVSTEQATAEIRNEATENATTIFEAAQKGSFQTIRYLLDNKLATVYDVDAQGATALHYAILANNDVCLKYLIDKGAVVDAPAGDLQATPLHWASRQGRLGAVHRLIKEGANPSLKDGQGFNALHLAVHSSHAMLVLYLLYLDIEIDTSDNVGGHTPLMWAAYQGHPQSVDLLLKFGASVTATDHSQLTPLHWAAVRGNKMCIRKMLEYGADVNARDQNGKSVMDFIKEKKFERVWDRAVLEFDVLAEGNPAQQDRIGKYPGSLGKPLPKRTVNIIAYIVPFITLGFALKCLAMFSWYAGLPLATMCFAITHISIVKYLVQVPSNDAVWKLPYFSSVFQSSAFWVVVTWLWVLVPSTSHLLFTHLIFLVTFFTAMFSFFKAMSSDPGFIRKDLSREKQRMAVEELADENMLDIRHFCLTCLIKKPLRSKHCKICNRCVAKFDHHCPWIFNCVGVRNHRPFILFLINMAIAIVTFALLSVNYLSITAPIYDRGPDSTCLLGSTVCGYFDYDTWTLSLTIWVLIQLTWSMFLLGVQLYQIAVAMTTNESANVNRYSYMKAPANGIVSSLPVGAVNGVEGSDGPSALPLNGEPQNHHHHHHHGGFCPCLQLVAGARALHKARNQPGSGVKRNVFDHGCWANCLDFWSDSTEGKSHGVNYYELYDIHQINYHNKSLTMEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N793</accession>
    <name>A0A1C7N793_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Chromatin remodeling factor mit1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">mit1</name>
        <name evidence="10" type="ORF">A0J61_07030</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000455">
        <property type="protein sequence ID" value="OBZ84917.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="FunCoup" id="A0A1C7N793">
        <property type="interactions" value="21"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N793"/>
    <dbReference type="InParanoid" id="A0A1C7N793"/>
    <dbReference type="OrthoDB" id="5857104at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000785">
        <property type="term" value="C:chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140658">
        <property type="term" value="F:ATP-dependent chromatin remodeler activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003682">
        <property type="term" value="F:chromatin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042393">
        <property type="term" value="F:histone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd18793">
        <property type="entry name" value="SF2_C_SNF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10810">
        <property type="entry name" value="Tandem AAA-ATPase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016197">
        <property type="entry name" value="Chromo-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056616">
        <property type="entry name" value="Chromo_MIT1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038718">
        <property type="entry name" value="SNF2-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049730">
        <property type="entry name" value="SNF2/RAD54-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000330">
        <property type="entry name" value="SNF2_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45623:SF17">
        <property type="entry name" value="CHROMODOMAIN-HELICASE-DNA-BINDING PROTEIN 3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45623">
        <property type="entry name" value="CHROMODOMAIN-HELICASE-DNA-BINDING PROTEIN 3-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23615">
        <property type="entry name" value="Chromo_MIT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00176">
        <property type="entry name" value="SNF2-rel_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54160">
        <property type="entry name" value="Chromo domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="8">
        <location>
            <begin position="501"/>
            <end position="668"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="9">
        <location>
            <begin position="796"/>
            <end position="947"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1086"/>
            <end position="1109"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1126"/>
            <end position="1155"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1172"/>
            <end position="1206"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="1373"/>
            <end position="1404"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="1133"/>
            <end position="1143"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="1178"/>
            <end position="1195"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OBZ84917.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="1449" mass="167363" checksum="AB77CE8EA9AEDCCE" modified="2016-11-30" version="1">MTTFTHVPESSIKDRFKPVEIKLDPWPYFFSSAKKILSEETSAHGKTTYKVQFVGNQIAEDQLGPLKDTVLAAYKTEKVERYARVQQISSSDSSDDSDVEHLAIARKRSLTTDSEEDSEDEFEFVATSRATARGRQVSKPRSYQEDFKHLNKLPKVYRSATKSTFTIPLYKNTSFIQHHASICFNCKRSGDCNSQEEVQIGKEEKRQRLLLCHHCSLSTHNNCIANLRMIDRASGRMKCGKCQLSHKCCGCQKSLLASDDQWEDETKSEKGVAFRCSTCFRGFHRGCVLKNVSPSLVKDHQDLVELYQSGLCMECSAFQNRTPQSIVSERSESKAGPEVLIKWKDESFRHTTWVLKDWICAFSPTLYRGYEKRKAEKGIPAVSDEWCIVDRILNVEWEDKAQTKASRILAVFKDTDYAEAVWDEPPSEDETEAYTEYKNALERYRLASKVQAPKGMDSLIKNVRKAATSEGYEKHALKEQPDFIQNGTLMKHQMEALNWLIYQWEKKQSCILADDMGLGKTIQIISFLYFLFKKFDIFPFLIVVPNSTATNWIREFAKWAPEMVVAPFFGYNAARDLALTYEILDRHKRIRCHVVVATYESILDPSPLHSAFWPVLIVDESQRLKNDESQLFRTLRSFRIDHTVLLTGTPLQNNLRELFNIMHFIHPKEFHGIEADNYEDMTAAQVEELHTRLRPHFLRRTKEEVLKKLPPKYELIVPVSMTPLQKEVYKQCISREIHETLAMTSGYKRQKGLSSIFTNLRKNLNHPYLLDGVEKPQPSPDLTQKNMIDACAKLKLFHQIFPKLKQKGHRILIFSTMTRALDVLEDYFHYEHILYTRIDGSTRERERVRNIDAFNAPNSKLDVFLLSTRAGGVGINLTTADTVIIWDSDFNPYADLQAISRAHRIGQTKMVLIYRLMTRLTIEEKVLQIGKKKMALEHVVVERMKADDEEKLEDIESILKYGTEALFADDDSKDIVYDEAAIDNLLNREQYRQVATEQQQKEIEASEEESKRENGGMNFSFAQVWQVDGTVKELDENQADEEKESDFWQKFLKEQQAAAEKKKQEQKIAEANLGRGARKRAQIVYTEKPGLDQPKPGKQGKQKEHDDEYVDVEEPMVIDVLELDELGDEDQGTPYNPQTSDQTRLPYHPTQHQQPVPQENLMHTFSTANKIPTHKQTHTPSQTSSMPSTSSSRPPLTHPAPDTTTITFDIQTPADHKSASPMTNVPTAPPPPPQVPIVLPNLPQQYKIHKLNQLYRISRKHIQSFQDFYSEEYKHNETPFARVHSAFQEVFSHFITEVNTIFVAEAAQERQIESNYGYPRVIIDHLYMQKQQTLSIALGEMIQYMEVEMNTFTLKKLREKYMKDMEIEEQKIRRDYQDKLSKLMKEQENQRSALLAEQASAQCKIRAHYTKLMPIIQPLPLPPTIVRQNNTDAEDSMQHLADHLRKEFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N7J1</accession>
    <name>A0A1C7N7J1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">SET domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">SET6</name>
        <name evidence="2" type="ORF">A0J61_06916</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000441">
        <property type="protein sequence ID" value="OBZ85031.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N7J1"/>
    <dbReference type="STRING" id="101091.A0A1C7N7J1"/>
    <dbReference type="InParanoid" id="A0A1C7N7J1"/>
    <dbReference type="OrthoDB" id="1028014at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd20071">
        <property type="entry name" value="SET_SMYD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.270.10">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050869">
        <property type="entry name" value="H3K4_H4K5_MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001214">
        <property type="entry name" value="SET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046341">
        <property type="entry name" value="SET_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12197">
        <property type="entry name" value="HISTONE-LYSINE N-METHYLTRANSFERASE SMYD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12197:SF294">
        <property type="entry name" value="POTENTIAL PROTEIN LYSINE METHYLTRANSFERASE SET6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00856">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82199">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50280">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SET" evidence="1">
        <location>
            <begin position="4"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="405"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ85031.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="405" mass="46632" checksum="14B32A0CE5B51F3D" modified="2016-11-30" version="1" fragment="single">MNNQYLQVAILPGKGRGYEATQTVEAGTIVHVSEPIAAIVSHEWTPETCFWCFEFSYPKKQKIKALTDQDRLTLLQAWGLCTAKQIKNNKLPVFLNNILFCSEHCRDAFKQSQSSLVEWEQLLAAYHRIDVEFKKIVPTTPPIEQVPISKTIDVWTLDSRDDEVLSHWLDQVWDILQDRPEICNREVEPSDITMCRLIATCIVRKNADQTLSTQPFENLMVIQNNELSHFRAHYDHLMLPELNPTSSVQALLLLQTLPAQVLDIIALYAFLKRALTAPLFNTPAIPSVTHALFRAILFRERANSFGLWEMPKQTQSQDEGAITDDLELLGWGIYPSAVYFNHSCDANVIKVREKRNIKFIARRTIEKGQEACISYGIVHEPVERRRARLLENYHFDCQCTRCIYE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N7L2</accession>
    <name>A0A1C7N7L2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_06811</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000429">
        <property type="protein sequence ID" value="OBZ85135.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N7L2"/>
    <dbReference type="InParanoid" id="A0A1C7N7L2"/>
    <dbReference type="OrthoDB" id="2222642at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="81"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="533"/>
            <end position="558"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ85135.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="574" mass="64622" checksum="A9E9457DCFA1B2B0" modified="2016-11-30" version="1">MFLTERILVTSIVSSAIFNITRLVYTFAFSITTTIIFSKLPGGSSTRFWYEQQDLLGKVMSYFFYPSGPTGTRGVKSTNTFGIVFLIITLALNFLPMLLEGLSPKVIVSLPGTQGPVLSPISNIFIPTLNEISLPHLSVPSKSKNATEKFLCSHIEGGCLDASNHTVAEIIWDAVDINPVKFYRDSSQDDLLVSFGDSFVAATVKPQFLQLAKDTLGSQTQYTTGLSFKIWNSNNLTGFISNAYAPNLENTTFGKYDILNSDQLTPLDTPDLSEMLKQGRRKGEPLPRNGSINRAERWTAIHRTSTLSSLLWQSVNAHSGTTDADWIMNCFFCQMIGIENYSSEAYLIQESLLNHPNNASRFNTFTIQSYVDQDFRLSTVLCTVEFNRTNSGVNYWCTHTFSQIWNVEHSKNPIDFYKDYNGDVANTDQFSDLSSTPFPYYPVPKDTENRTSYIPVVPIFEIRSIGQCRTDWNFRTQTLQSWMKECASRNLGQLTQDELKLIAGNIWQIASTITTRGFLINVKHWVPTIRIHISLAAIIVIGAGVGFFVIANLVYFTVINPAHRRSLYESIRHR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N8P2</accession>
    <name>A0A1C7N8P2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Pyruvate dehydrogenase E1 component subunit alpha</fullName>
            <ecNumber evidence="5">1.2.4.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">PDA1</name>
        <name evidence="7" type="ORF">A0J61_06955</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9 5">
            <text>N(6)-[(R)-lipoyl]-L-lysyl-[protein] + pyruvate + H(+) = N(6)-[(R)-S(8)-acetyldihydrolipoyl]-L-lysyl-[protein] + CO2</text>
            <dbReference type="Rhea" id="RHEA:19189"/>
            <dbReference type="Rhea" id="RHEA-COMP:10474"/>
            <dbReference type="Rhea" id="RHEA-COMP:10478"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:83099"/>
            <dbReference type="ChEBI" id="CHEBI:83111"/>
            <dbReference type="EC" id="1.2.4.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 5">
            <name>thiamine diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58937"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.2.4.1" evidence="5"/>
    <dbReference type="EMBL" id="LUGH01000445">
        <property type="protein sequence ID" value="OBZ84999.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N8P2"/>
    <dbReference type="FunCoup" id="A0A1C7N8P2">
        <property type="interactions" value="157"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N8P2"/>
    <dbReference type="InParanoid" id="A0A1C7N8P2"/>
    <dbReference type="OrthoDB" id="10256198at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042645">
        <property type="term" value="C:mitochondrial nucleoid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045254">
        <property type="term" value="C:pyruvate dehydrogenase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004739">
        <property type="term" value="F:pyruvate dehydrogenase (acetyl-transferring) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007124">
        <property type="term" value="P:pseudohyphal growth"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006086">
        <property type="term" value="P:pyruvate decarboxylation to acetyl-CoA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd02000">
        <property type="entry name" value="TPP_E1_PDC_ADC_BCADC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.970:FF:000013">
        <property type="entry name" value="Pyruvate dehydrogenase E1 component subunit alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.970">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001017">
        <property type="entry name" value="DH_E1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050642">
        <property type="entry name" value="PDH_E1_Alpha_Subunit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017597">
        <property type="entry name" value="Pyrv_DH_E1_asu_subgrp-y"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029061">
        <property type="entry name" value="THDP-binding"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR03182">
        <property type="entry name" value="PDH_E1_alph_y"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11516:SF60">
        <property type="entry name" value="PYRUVATE DEHYDROGENASE E1 COMPONENT SUBUNIT ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11516">
        <property type="entry name" value="PYRUVATE DEHYDROGENASE E1 COMPONENT, ALPHA SUBUNIT BACTERIAL AND ORGANELLAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00676">
        <property type="entry name" value="E1_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52518">
        <property type="entry name" value="Thiamin diphosphate-binding fold (THDP-binding)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4 5 7" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0786">Thiamine pyrophosphate</keyword>
    <feature type="domain" description="Dehydrogenase E1 component" evidence="6">
        <location>
            <begin position="68"/>
            <end position="361"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU361139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OBZ84999.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="390" mass="42928" checksum="BE8F2169613A9EC7" modified="2016-11-30" version="1">MLRSASRLFAAKRVAAFTPMRALSTSMPRFSDKLSITLPETSFETYNCEKPGLEVEVTKEELLDMYNKMTVMRRMEMVADGLYKAKKIRGFCHLCNGQEAVSVGMEAAITKTDHVITAYRCHGFTYLRGGSVESILAELMGRSTGISKGKGGSMHMFAESFYGGNGIVGAQVPLGAGVAFAQKYLENPSVTFSLYGDGASNQGQVFEAYNMAKLWDLPVVFVCENNKYGMGTAANRSSASTEYYKRGDYIPGLKVNGMDVLSVLKACQYAKEWTTSGKGPLVMEMATYRYGGHSMSDPGTTYRTREEIQHMRSTSDPITGLKAILIDNGVATEAELKEMDKEARKMVDEASKKAQAAPEPSLSEFHTNIYIPGSEPTVVRGREPNEVYHY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N8T9</accession>
    <name>A0A1C7N8T9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Zinc finger protein ZPR1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">Zpr1</name>
        <name evidence="8" type="ORF">A0J61_06424</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Acts as a protein folding chaperone for elongation factor 1-alpha.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the ZPR1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000387">
        <property type="protein sequence ID" value="OBZ85523.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N8T9"/>
    <dbReference type="FunCoup" id="A0A1C7N8T9">
        <property type="interactions" value="941"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N8T9"/>
    <dbReference type="InParanoid" id="A0A1C7N8T9"/>
    <dbReference type="OrthoDB" id="308464at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044183">
        <property type="term" value="F:protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061770">
        <property type="term" value="F:translation elongation factor binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006458">
        <property type="term" value="P:'de novo' protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000086">
        <property type="term" value="P:G2/M transition of mitotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009749">
        <property type="term" value="P:response to glucose"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="FunFam" id="2.20.25.420:FF:000001">
        <property type="entry name" value="Zinc finger protein ZPR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.20.25.420:FF:000002">
        <property type="entry name" value="Zinc finger protein ZPR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.120.1040:FF:000003">
        <property type="entry name" value="Zinc finger protein zpr1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.120.1040:FF:000006">
        <property type="entry name" value="Zinc finger protein zpr1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.1040">
        <property type="entry name" value="ZPR1, A/B domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.25.420">
        <property type="entry name" value="ZPR1, zinc finger domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004457">
        <property type="entry name" value="Znf_ZPR1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040141">
        <property type="entry name" value="ZPR1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042451">
        <property type="entry name" value="ZPR1_A/B_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056180">
        <property type="entry name" value="ZPR1_jr_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042452">
        <property type="entry name" value="ZPR1_Znf1/2"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00310">
        <property type="entry name" value="ZPR1_znf"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10876">
        <property type="entry name" value="ZINC FINGER PROTEIN ZPR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10876:SF0">
        <property type="entry name" value="ZINC FINGER PROTEIN ZPR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22794">
        <property type="entry name" value="jr-ZPR1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03367">
        <property type="entry name" value="Zn_ribbon_ZPR1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00709">
        <property type="entry name" value="Zpr1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Zinc finger ZPR1-type" evidence="7">
        <location>
            <begin position="19"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="domain" description="Zinc finger ZPR1-type" evidence="7">
        <location>
            <begin position="244"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="414"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="414"/>
            <end position="423"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008354"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00054139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00709"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OBZ85523.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="434" mass="48377" checksum="3A3AB28D1A0E912E" modified="2016-11-30" version="1">MSEPIFVDLSETKPTEIESLCMRCQENGTTRILLSKIPHFREIIIMAFECPHCGFRNNELQSAGTFNERGHTITLTVKGKEDMNRQLVKSDYCSVKFEELDMEIPANNNRGLLTTVEGLITNAIEDLSAGQPIRKATDEAVFNKIEEIIATMNSYKEGTPLTLTLDDPSGNSYIENKCLPQQDPQIKLRWYTRTPEQQAFLGLQVGSDQTPAEAAAAEVIRRGVTASDMVNEKTGLPEVMSFPANCPSCSSPCATNMHVMEIPHFKEVVIMATNCEQCGYKSNEVKAGGPISEKGKRITLKITDPEDLSRDILKSETCGLSIPEINLELTQGTLGGRFTTVEGLLRQVHTDLRDRANFIEVADGLKMPVTLIIDDPLSNSYLQNLYAPDPDPEMIIEDYERSWEVNEDLGLNDMKLDNYEDPKNVNANTEEESA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N8U8</accession>
    <name>A0A1C7N8U8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Haloacid dehalogenase-like hydrolase domain-containing protein 2</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">Phospholysine phosphohistidine inorganic pyrophosphate phosphatase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="primary">HDHD2</name>
        <name evidence="13" type="ORF">A0J61_06421</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Phosphatase that hydrolyzes imidodiphosphate, 3-phosphohistidine and 6-phospholysine. Has broad substrate specificity and can also hydrolyze inorganic diphosphate, but with lower efficiency.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the HAD-like hydrolase superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000387">
        <property type="protein sequence ID" value="OBZ85531.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N8U8"/>
    <dbReference type="STRING" id="101091.A0A1C7N8U8"/>
    <dbReference type="InParanoid" id="A0A1C7N8U8"/>
    <dbReference type="OrthoDB" id="426235at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016791">
        <property type="term" value="F:phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016462">
        <property type="term" value="F:pyrophosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1000:FF:000051">
        <property type="entry name" value="Phospholysine phosphohistidine inorganic pyrophosphate phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006357">
        <property type="entry name" value="HAD-SF_hydro_IIA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006355">
        <property type="entry name" value="LHPP/HDHD2"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01460">
        <property type="entry name" value="HAD-SF-IIA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01458">
        <property type="entry name" value="HAD-SF-IIA-hyp3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19288">
        <property type="entry name" value="4-NITROPHENYLPHOSPHATASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19288:SF46">
        <property type="entry name" value="HALOACID DEHALOGENASE-LIKE HYDROLASE DOMAIN-CONTAINING PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13344">
        <property type="entry name" value="Hydrolase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13242">
        <property type="entry name" value="Hydrolase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7 13" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00037258"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00039357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00039666"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="OBZ85531.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="264" mass="29172" checksum="9DE4E9EAA9AFF791" modified="2016-11-30" version="1">MSVIKGVLIDLSGTIHIDAKVIPGAVEAIQRLKKSQIPFRFATNTTKVSSKKLVEKLTKLGFDVKEKEVFTSLSACRNLLETQQLRPLLLMEDEALDEFSHIDQTNPNAVVVGLAPSKFNYEKLNQAFRLLSSDSNVSLIAIHKAKYFADKDEKLSMGPGGFVQALEFASGTTAQVVGKPTIDFFKLALQQIHMEHEPHQVAIIGDDLSNDLGGGAKELGLHRFLVQTGKYRSQDMDHKEEGVQVFKSVVEAIDHIIGQYHSDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N8Z8</accession>
    <name>A0A1C7N8Z8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">60S acidic ribosomal protein P1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">CLAH12_1</name>
        <name evidence="6" type="synonym">CLAH12_2</name>
        <name evidence="6" type="ORF">A0J61_04685</name>
        <name evidence="5" type="ORF">A0J61_06854</name>
    </gene>
    <organism evidence="5 7">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 7" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the eukaryotic ribosomal protein P1/P2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000434">
        <property type="protein sequence ID" value="OBZ85099.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="LUGH01000234">
        <property type="protein sequence ID" value="OBZ87263.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N8Z8"/>
    <dbReference type="FunCoup" id="A0A1C7N8Z8">
        <property type="interactions" value="346"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N8Z8"/>
    <dbReference type="InParanoid" id="A0A1C7N8Z8"/>
    <dbReference type="OrthoDB" id="2194681at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022625">
        <property type="term" value="C:cytosolic large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030295">
        <property type="term" value="F:protein kinase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043021">
        <property type="term" value="F:ribonucleoprotein complex binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002181">
        <property type="term" value="P:cytoplasmic translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006414">
        <property type="term" value="P:translational elongation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05831">
        <property type="entry name" value="Ribosomal_P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.1410:FF:000001">
        <property type="entry name" value="60S acidic ribosomal protein P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.1410">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01478">
        <property type="entry name" value="Ribosomal_L12_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038716">
        <property type="entry name" value="P1/P2_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027534">
        <property type="entry name" value="Ribosomal_P1/P2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45696">
        <property type="entry name" value="60S ACIDIC RIBOSOMAL PROTEIN P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45696:SF10">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00428">
        <property type="entry name" value="Ribosomal_60s"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 5" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="71"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="71"/>
            <end position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005436"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OBZ85099.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OBZ87263.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="106" mass="10690" checksum="909E6EF181BEE0F0" modified="2016-11-30" version="1">MSAELAVVYAALILEDDNIEITADKLQALVAAAGIEVEPIWFSLYAKALAGQDLKALLLNVGAPGAGPAVAAGGAAAGGAADAPAEEEKAEEKEESDDDMGFGLFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N9X1</accession>
    <name>A0A1C7N9X1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Cytokinesis protein sepH</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">sepH_0</name>
        <name evidence="7" type="ORF">A0J61_06063</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000349">
        <property type="protein sequence ID" value="OBZ85877.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N9X1"/>
    <dbReference type="STRING" id="101091.A0A1C7N9X1"/>
    <dbReference type="InParanoid" id="A0A1C7N9X1"/>
    <dbReference type="OrthoDB" id="8693905at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001245">
        <property type="entry name" value="Ser-Thr/Tyr_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11584:SF369">
        <property type="entry name" value="MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 19-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11584">
        <property type="entry name" value="SERINE/THREONINE PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00109">
        <property type="entry name" value="TYRKINASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="6">
        <location>
            <begin position="1"/>
            <end position="203"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OBZ85877.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="434" mass="49437" checksum="D39A429E0DD1FCFD" modified="2016-11-30" version="1">MLKTLSHANVVKYVGFIPSERYFDVVLEYAENGSLMSTLKAFGAFPEKLVASFCIKILHGLQYLHDNQVVHCDLKAANILTTKTGDVKLTDFGVSLNLKLKPVDSDTIAGTPNWMAPEVIELEGATTKSDIWSLGCTLIELITGKPPYSQLLAMSAMFHIVEDEYPPLPQNISSEMRDFLLCCFQKNPKKRPSSQQLQNHVWIRQHQQQKGLSSKKLSSDTKYQASKKSYQGLQTRYYSLNANSTLDENHNHQFIQTSFGKDVECKVCNKALSSKSLFCESKSDSMNTQIKECKKMALSCPPRIHDQQPSYEVSYLLFYQVVSTDFFSSDYQWLFSAKVYNRSYKERQGQRGQVPIEFLRKSLQEHPQADSIRKYSKALGLTEQEQLALCENPALLEHTMTMERFQLATPVASNEPFNKTKKKKELEESFPVLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NA16</accession>
    <name>A0A1C7NA16_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Zinc finger protein ZIC 5</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">zic5</name>
        <name evidence="12" type="ORF">A0J61_05976</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the GLI C2H2-type zinc-finger protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000341">
        <property type="protein sequence ID" value="OBZ85973.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NA16"/>
    <dbReference type="InParanoid" id="A0A1C7NA16"/>
    <dbReference type="OrthoDB" id="654211at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000532">
        <property type="entry name" value="GLIS family zinc finger 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:002343">
        <property type="entry name" value="Zinc finger protein 33A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043359">
        <property type="entry name" value="GLI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048420">
        <property type="entry name" value="Zap1-like_Znf1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056436">
        <property type="entry name" value="Znf-C2H2_ZIC1-5/GLI1-3-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45718:SF8">
        <property type="entry name" value="GLIS FAMILY ZINC FINGER 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45718">
        <property type="entry name" value="TRANSCRIPTIONAL ACTIVATOR CUBITUS INTERRUPTUS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21816">
        <property type="entry name" value="Zap1_zf1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23561">
        <property type="entry name" value="zf-C2H2_15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <keyword evidence="5 9" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="11">
        <location>
            <begin position="485"/>
            <end position="515"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="11">
        <location>
            <begin position="518"/>
            <end position="550"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="11">
        <location>
            <begin position="551"/>
            <end position="580"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="11">
        <location>
            <begin position="581"/>
            <end position="610"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="86"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="376"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="436"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="678"/>
            <end position="709"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="436"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="465"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="679"/>
            <end position="701"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010831"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="OBZ85973.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="709" mass="79294" checksum="C46E6F0E90596590" modified="2016-11-30" version="1">MDLQQTKLTPNLTQLDVVNKPPTPSTNEFFPSRFEGLQSPQPPPFVSITSSASVPTTTTTENPPAMQRLFSHQDMLSTADVSLSTLTSPPANRISSINSTSPSRQATPLSIVTSPTQLIPMANNTNPNLLNENALLMHHNNTNSIFDMAESPNRLSTLFSPYQPPSTPQDHMMMNNQAGIDHHPIVPSQRMMTQPSTTDEENERVAAAAQQVMAQQMAMAQQFAVMQPMTPTELVQTPSQETPHVVLSQMANINSSAPSTPIATTPTQQMHQVKSDNISLHDAIVHHQHQQQQQQKGMVFIDESIRSVKRGFMDLNESSKKKSRRHTVSTAYRPTLNIDTKNLIHSANAPRSAAVSSPTMAYNSFQPHVPSQMYTXNEPKPSMVEQKQPLSITLPPPPTPQELGLKTETTQVTAKDYENMSREQLIARLIRLETEKQASDTGDTSHEEQGLPAFSQTDEDKSTVDDDEEEEEETGETANETDLQLQCKWKDCGDSFSSLQKLISHINDTHVGSGKATYCCEWEGCARNQKPFTKRHKMYNHLRTHTGERPFVCDKPNCGKRFSRPDSLTTHVKTHSNVRPYICVAKGCGKAYYHSRSLKKHEKTHETAQYNSSFNVAPMDYVNSQLHRPIHTQSLPSSPHPQLHTPTSQASFALLQQANKPYTPNTNHLLSFTPAGMVEQQQQQHQQQQHEPQPLLTQPHPMFDSENQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NA53</accession>
    <name>A0A1C7NA53_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Helitron helicase-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_06114</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000353">
        <property type="protein sequence ID" value="OBZ85838.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NA53"/>
    <dbReference type="STRING" id="101091.A0A1C7NA53"/>
    <dbReference type="InParanoid" id="A0A1C7NA53"/>
    <dbReference type="OrthoDB" id="2285856at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10492">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10492:SF57">
        <property type="entry name" value="ATP-DEPENDENT DNA HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="300"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ85838.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="300" mass="35198" checksum="063279F6B91434D4" modified="2016-11-30" version="1" fragment="single">MDERSHRVQIRDKQTNEMKSVYLTNQNVVPYNPFLTKKYKAHINVELCGSVGAIKYINKYVYKRPGRTTVHLKNENDEIERYLISRYIGPTEAVWCLFKYAMHEEDPSVTSLAIHLENEQPVYFDPEASAEEIQLIIDNTHSTLMGFFKYNTTNEDGRGYLYQEFPTYFTWKKNERKWQARKKGFAVGRMYYCTPTAGERFFLRLLLIVVRGPTSFQDLRTVNSVVFDTFREACQALHLIEDDQEWFKCFPEAVVFVSGSSLRSLLISALLFQELNQPAALWNEFCLSICDDHDVRMRQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NAF1</accession>
    <name>A0A1C7NAF1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_06274</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000371">
        <property type="protein sequence ID" value="OBZ85679.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NAF1"/>
    <dbReference type="FunCoup" id="A0A1C7NAF1">
        <property type="interactions" value="15"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NAF1"/>
    <dbReference type="InParanoid" id="A0A1C7NAF1"/>
    <dbReference type="OrthoDB" id="2209940at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.150">
        <property type="entry name" value="Haem-degrading domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00761">
        <property type="entry name" value="UPF0303"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005624">
        <property type="entry name" value="PduO/GlcC-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038084">
        <property type="entry name" value="PduO/GlcC-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010371">
        <property type="entry name" value="YBR137W-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF002696">
        <property type="entry name" value="PRK02487.1-5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28255">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28255:SF1">
        <property type="entry name" value="UPF0303 PROTEIN YBR137W"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03928">
        <property type="entry name" value="HbpS-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF008757">
        <property type="entry name" value="UCP008757"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143744">
        <property type="entry name" value="GlcG-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ85679.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="156" mass="17540" checksum="D7751E46E1845F12" modified="2016-11-30" version="1">MSDLKQLVASIVEQEEKCQFTSFTSEDALKLGLLLIEKAKPYKKSVVIDITLGDHQLFHYAMDGTSKDNDEWVRRKNNTVNRFGRSSYYVGRNLASQNKTIEEKYFVSESDYATHGGAFPLKIKNVGVVGTITVSGLAQQDDHNLVADTIQEYISQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NAG7</accession>
    <name>A0A1C7NAG7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_05995</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000342">
        <property type="protein sequence ID" value="OBZ85958.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NAG7"/>
    <dbReference type="InParanoid" id="A0A1C7NAG7"/>
    <dbReference type="OrthoDB" id="2281772at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ85958.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="122" mass="13981" checksum="FFB497EA03CF227A" modified="2016-11-30" version="1">MPFILSPVDNTNNLEAFKRIIRNYQHVIERNPTACCMIGFTAARMIRDVEGELIDLEDMELWLQSLENESNDTGMASTERLDQIEKILHMIGETEPTTLSNKSEDLVDNTYYTTLNYTSSSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NBR0</accession>
    <name>A0A1C7NBR0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Threonine--tRNA ligase, cytoplasmic</fullName>
            <ecNumber evidence="3">6.1.1.3</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Threonyl-tRNA synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="16" type="primary">THS1</name>
        <name evidence="16" type="ORF">A0J61_05764</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>tRNA(Thr) + L-threonine + ATP = L-threonyl-tRNA(Thr) + AMP + diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:24624"/>
            <dbReference type="Rhea" id="RHEA-COMP:9670"/>
            <dbReference type="Rhea" id="RHEA-COMP:9704"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57926"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78534"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.3"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the class-II aminoacyl-tRNA synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.3" evidence="3"/>
    <dbReference type="EMBL" id="LUGH01000321">
        <property type="protein sequence ID" value="OBZ86189.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NBR0"/>
    <dbReference type="FunCoup" id="A0A1C7NBR0">
        <property type="interactions" value="385"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NBR0"/>
    <dbReference type="InParanoid" id="A0A1C7NBR0"/>
    <dbReference type="OrthoDB" id="5423599at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004829">
        <property type="term" value="F:threonine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006435">
        <property type="term" value="P:threonyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01667">
        <property type="entry name" value="TGS_ThrRS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00860">
        <property type="entry name" value="ThrRS_anticodon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00771">
        <property type="entry name" value="ThrRS_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.930.10:FF:000009">
        <property type="entry name" value="Threonine--tRNA ligase 2, cytoplasmic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.20.30:FF:000006">
        <property type="entry name" value="Threonine--tRNA ligase, cytoplasmic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.980.10:FF:000005">
        <property type="entry name" value="Threonyl-tRNA synthetase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.800">
        <property type="entry name" value="Anticodon-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="entry name" value="Bira Bifunctional Protein, Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.980.10">
        <property type="entry name" value="Threonyl-trna Synthetase, Chain A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00184">
        <property type="entry name" value="Thr_tRNA_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002314">
        <property type="entry name" value="aa-tRNA-synt_IIb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006195">
        <property type="entry name" value="aa-tRNA-synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004154">
        <property type="entry name" value="Anticodon-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036621">
        <property type="entry name" value="Anticodon-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012675">
        <property type="entry name" value="Beta-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004095">
        <property type="entry name" value="TGS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012676">
        <property type="entry name" value="TGS-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002320">
        <property type="entry name" value="Thr-tRNA-ligase_IIa"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018163">
        <property type="entry name" value="Thr/Ala-tRNA-synth_IIc_edit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047246">
        <property type="entry name" value="ThrRS_anticodon"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033728">
        <property type="entry name" value="ThrRS_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012947">
        <property type="entry name" value="tRNA_SAD"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00418">
        <property type="entry name" value="thrS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11451:SF46">
        <property type="entry name" value="THREONINE--TRNA LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11451">
        <property type="entry name" value="THREONINE-TRNA LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03129">
        <property type="entry name" value="HGTP_anticodon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02824">
        <property type="entry name" value="TGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00587">
        <property type="entry name" value="tRNA-synt_2b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07973">
        <property type="entry name" value="tRNA_SAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01047">
        <property type="entry name" value="TRNASYNTHTHR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00863">
        <property type="entry name" value="tRNA_SAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52954">
        <property type="entry name" value="Class II aaRS ABD-related"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="Class II aaRS and biotin synthetases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81271">
        <property type="entry name" value="TGS-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55186">
        <property type="entry name" value="ThrRS/AlaRS common domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50862">
        <property type="entry name" value="AA_TRNA_LIGASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51880">
        <property type="entry name" value="TGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 16" id="KW-0436">Ligase</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TGS" evidence="15">
        <location>
            <begin position="64"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="domain" description="Aminoacyl-transfer RNA synthetases class-II family profile" evidence="14">
        <location>
            <begin position="332"/>
            <end position="605"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="10"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00031900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00049515"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00073157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="OBZ86189.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="716" mass="81492" checksum="57B03731A47FFE6C" modified="2016-11-30" version="1">MSAPEQTVPKNEKKAKAPKAKKDANASAYPLEMTPPPEYLQHRIDMFDKLKAAADAEVAKQPREPITITLPDGSTKEGTSWETSPMTIAAGIAKSLAERTVIAKVDGELWDLTRPLEKSCKLELLDFENDEGKMVFWHSSAHMLGEACERHYGCNLCIGPPLKEGGFYYEMGLADRVVSQTDYPNLEKLVNQFAKEKQTFERLVISKEDILEMFKHNPYKVHIIKDKIPDGSSTTVYRCGPLIDLCRGPHVPHTGRVKAFSVTKNSASYFLGDAKNDSLQRLYGISFPDKKLMTEYKQFIEEAAKRDHRKIGKEQELFFFHELSPGSAFMLPHGARVYNALMGLIKDEYQQRGFTEVITPNMFNLKLWNQSGHAQKYKENMFCLEVDKEEFALKPMNCPGHCLMFGHKERSYRDLPVRFADFGVLHRNEFSGALSGLTRVRRFQQDDAHIFCRIDQIEQEMAGCFDFLDKVYGIFGFDFHLKLSTRPENYIGELDVWNKAEKMLEDSLNRFTAQKGTTWDVDPGDGAFYGPKIDIVISDALRRKHQCATIQLDFQLPERFKLEYRTDGTGAEDAMARPVIIHRAILGSVERMMGIVIEHFAGKFPFWLSPRQIQVVPVAQAFNGYAKEIVDQLVKLGVYADADLGDNTLNKKIRNAELAHYNFIFVVGEVEQNTRSVNVRNRDDVGTKAKGQTVPLEQVIESVQRLKTERSLENKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-06-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NCP2</accession>
    <name>A0A1C7NCP2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_05097</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000266">
        <property type="protein sequence ID" value="OBZ86855.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NCP2"/>
    <dbReference type="InParanoid" id="A0A1C7NCP2"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ86855.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="70" mass="8254" checksum="5D62BD59EFC13E93" modified="2016-11-30" version="1">MLDKAACRKYKQVPWTDLLSGEAGSLQLRDWPRYDSDTSKKGKYQLQNLTVSQLQDIKDKLDMNIIFYKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NCX6</accession>
    <name>A0A1C7NCX6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_04970</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000255">
        <property type="protein sequence ID" value="OBZ86982.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NCX6"/>
    <dbReference type="InParanoid" id="A0A1C7NCX6"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="51"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="92"/>
            <end position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ86982.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="115" mass="12670" checksum="4F4AB486FB2609C4" modified="2016-11-30" version="1">MLHHLVGDANNTKLWLVQLSSSSLMLLESLMHRIPNYHPNLVKSVCALFPIPYMVICTARAVCALLIVTTMIQKGWFLNVYPKTSANTPPDSIFALIFVLTVTTIASCSPALAKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7ND01</accession>
    <name>A0A1C7ND01_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Mitochondrial inner membrane protein COX18</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">COX18</name>
        <name evidence="9" type="ORF">A0J61_04936</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Membrane</location>
            <topology evidence="1 6">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the OXA1/ALB3/YidC family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000253">
        <property type="protein sequence ID" value="OBZ87012.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7ND01"/>
    <dbReference type="FunCoup" id="A0A1C7ND01">
        <property type="interactions" value="48"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7ND01"/>
    <dbReference type="InParanoid" id="A0A1C7ND01"/>
    <dbReference type="OrthoDB" id="2148490at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032977">
        <property type="term" value="F:membrane insertase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033617">
        <property type="term" value="P:mitochondrial respiratory chain complex IV assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032979">
        <property type="term" value="P:protein insertion into mitochondrial inner membrane from matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd20069">
        <property type="entry name" value="5TM_Oxa1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001708">
        <property type="entry name" value="YidC/ALB3/OXA1/COX18"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028055">
        <property type="entry name" value="YidC/Oxa/ALB_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12428:SF65">
        <property type="entry name" value="CYTOCHROME C OXIDASE ASSEMBLY PROTEIN COX18, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12428">
        <property type="entry name" value="OXA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02096">
        <property type="entry name" value="60KD_IMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="167"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="225"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="266"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="domain" description="Membrane insertase YidC/Oxa/ALB C-terminal" evidence="8">
        <location>
            <begin position="79"/>
            <end position="295"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009877"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003945"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02096"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OBZ87012.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="319" mass="35982" checksum="E261995CC9633DEF" modified="2016-11-30" version="1">MWCIRSRPTAIRKQIVPILQRSSTQLNPSSHSDPPTSWPLSSSLIATTAIDPNSLDASLPAVLATNESILQAIHTSLPWWATIVSSTILLRSCLTLPIAIYQQKSIGTMIQLAPMVQSWGETLKQELGKRSKHQGWSYPEYQAQLQKQYRYKVNTIYAHYGCPRWKLLLLPYVQMPLFICMSLTLRHMTAMPLPYWGQTASEPVAGLSEEGLAWFTDLTLTDPTLTLPVLIGVGNLLNVEMNAWYARKTQTFKQKVMTNIMRAVSIAFVPIAAHTPMSIGLYWFSSAWYSVIQNVSFRVPAVRKALGMPLFDKLKKEQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7ND35</accession>
    <name>A0A1C7ND35_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Protein ras-2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">ras-2_0</name>
        <name evidence="4" type="ORF">A0J61_06661</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000413">
        <property type="protein sequence ID" value="OBZ85284.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7ND35"/>
    <dbReference type="STRING" id="101091.A0A1C7ND35"/>
    <dbReference type="InParanoid" id="A0A1C7ND35"/>
    <dbReference type="OrthoDB" id="5976022at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:001423">
        <property type="entry name" value="Ras family GTPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001806">
        <property type="entry name" value="Small_GTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020849">
        <property type="entry name" value="Small_GTPase_Ras-type"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24070">
        <property type="entry name" value="RAS, DI-RAS, AND RHEB FAMILY MEMBERS OF SMALL GTPASE SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00071">
        <property type="entry name" value="Ras"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00449">
        <property type="entry name" value="RASTRNSFRMNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00175">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00176">
        <property type="entry name" value="RAN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00173">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00174">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51419">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51421">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="161"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="167"/>
            <end position="182"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OBZ85284.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="182" mass="20753" checksum="5C798F812FCBC3CD" modified="2016-11-30" version="1">MMLYKLVVLGDGGVGKTALTIQTYDPTIEDSYRKQVVIDDQPCILEVLDTAGQEEYTALRDQWIRDGEGFLLVYSITSRSTYDRIERFRDQIFRVKDAENVPLMLVGNKCDKVTEREVTREEGYATAKRLACDFIETSAKTCVNVERSFYQVVKAIRAQREGSHAGPKGKPKKEKKNKCMIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NDH8</accession>
    <name>A0A1C7NDH8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">BHLH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">A0J61_04824</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000244">
        <property type="protein sequence ID" value="OBZ87131.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NDH8"/>
    <dbReference type="STRING" id="101091.A0A1C7NDH8"/>
    <dbReference type="InParanoid" id="A0A1C7NDH8"/>
    <dbReference type="OrthoDB" id="5778525at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.280.10">
        <property type="entry name" value="Helix-loop-helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011598">
        <property type="entry name" value="bHLH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036638">
        <property type="entry name" value="HLH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052207">
        <property type="entry name" value="Max-like/E-box_TFs"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15741">
        <property type="entry name" value="BASIC HELIX-LOOP-HELIX ZIP TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15741:SF27">
        <property type="entry name" value="TRANSCRIPTION FACTOR AP-4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00010">
        <property type="entry name" value="HLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00353">
        <property type="entry name" value="HLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47459">
        <property type="entry name" value="HLH, helix-loop-helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50888">
        <property type="entry name" value="BHLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="BHLH" evidence="7">
        <location>
            <begin position="181"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="242"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="248"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="266"/>
            <end position="295"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50888"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OBZ87131.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="375" mass="43282" checksum="FFDFED72A0AAFF55" modified="2016-11-30" version="1">MSTKDRQIQEPVPFEDFKFSLDFPQDPFLQQSPTLDFAAPSTHAILDEHDQKAFSSFLDAFFMDSDTIPQPSFEHGHLFYHEDNPAALVTHTLPSSSYYEEQRRHSILQSLDEQKKKLQLNHEPQTIYLRSSDTLKSPYTFYSDSKKRRYSFDEDIKRPQSIAPLPVKKQRTTKELLTEEEKKANHIASEQKRRSTIRHGFKELTELIPTLKNVNHSKSVVLFKAAEFIQNLEKRNKHLRHKLESLKLRTQSCSQSPPRMDQRRASSSSSTDSSSGNSHDSSTSASTATTTTLNTQYDLSDPLRDLPIETKKALMMHKTQQEELMLYQEQLQQSSLFRANKLPPILGQYGHKSINDHTLLRDFQDKTIPATMNIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NDX2</accession>
    <name>A0A1C7NDX2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Prefoldin subunit 4</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">GIM3</name>
        <name evidence="6" type="ORF">A0J61_04974</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3 4">Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Heterohexamer of two PFD-alpha type and four PFD-beta type subunits.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the prefoldin subunit beta family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000256">
        <property type="protein sequence ID" value="OBZ86969.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NDX2"/>
    <dbReference type="FunCoup" id="A0A1C7NDX2">
        <property type="interactions" value="398"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NDX2"/>
    <dbReference type="InParanoid" id="A0A1C7NDX2"/>
    <dbReference type="OrthoDB" id="10250441at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016272">
        <property type="term" value="C:prefoldin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015631">
        <property type="term" value="F:tubulin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071629">
        <property type="term" value="P:cytoplasm protein quality control by the ubiquitin-proteasome system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032968">
        <property type="term" value="P:positive regulation of transcription elongation by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007021">
        <property type="term" value="P:tubulin complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd23165">
        <property type="entry name" value="Prefoldin_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.370:FF:000005">
        <property type="entry name" value="Prefoldin subunit 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.370">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002777">
        <property type="entry name" value="PFD_beta-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016661">
        <property type="entry name" value="PFDN4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009053">
        <property type="entry name" value="Prefoldin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21100">
        <property type="entry name" value="PREFOLDIN SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21100:SF9">
        <property type="entry name" value="PREFOLDIN SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01920">
        <property type="entry name" value="Prefoldin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016477">
        <property type="entry name" value="Prefoldin_subunit_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46579">
        <property type="entry name" value="Prefoldin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4" id="KW-0143">Chaperone</keyword>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="31"/>
            <end position="122"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008045"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00024667"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRNR" id="PIRNR016477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OBZ86969.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="136" mass="15713" checksum="EB95EE018852E7BD" modified="2016-11-30" version="1">MSNIRMLNQKEEANGGDVEVSWVDQQRINEFSKYNAKIDDLEEKYQKLKQEKEYLDDVAMELELADEDEAVRYKVGDAFVHVSASEAVERVEKDSEKLGLEIDDVKQQMDAVQTKMSELKKELYAKFGSAINLEKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NDZ0</accession>
    <name>A0A1C7NDZ0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Methyltransferase-like protein 13</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">Mettl13</name>
        <name evidence="9" type="ORF">A0J61_06359</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000381">
        <property type="protein sequence ID" value="OBZ85584.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NDZ0"/>
    <dbReference type="STRING" id="101091.A0A1C7NDZ0"/>
    <dbReference type="InParanoid" id="A0A1C7NDZ0"/>
    <dbReference type="OrthoDB" id="411785at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003910">
        <property type="term" value="F:DNA ligase (ATP) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.150:FF:000217">
        <property type="entry name" value="Methyltransferase protein 13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.470.30">
        <property type="entry name" value="DNA ligase/mRNA capping enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012310">
        <property type="entry name" value="DNA_ligase_ATP-dep_cent"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029319">
        <property type="entry name" value="DNA_ligase_OB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041698">
        <property type="entry name" value="Methyltransf_25"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050326">
        <property type="entry name" value="NAD_dep_DNA_ligaseB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47810">
        <property type="entry name" value="DNA LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47810:SF1">
        <property type="entry name" value="DNA LIGASE B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01068">
        <property type="entry name" value="DNA_ligase_A_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14743">
        <property type="entry name" value="DNA_ligase_OB_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13649">
        <property type="entry name" value="Methyltransf_25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56091">
        <property type="entry name" value="DNA ligase/mRNA capping enzyme, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0227">DNA damage</keyword>
    <keyword evidence="5" id="KW-0234">DNA repair</keyword>
    <keyword evidence="3" id="KW-0235">DNA replication</keyword>
    <keyword evidence="2" id="KW-0436">Ligase</keyword>
    <keyword evidence="9" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransferase" evidence="7">
        <location>
            <begin position="60"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="domain" description="ATP-dependent DNA ligase family profile" evidence="6">
        <location>
            <begin position="360"/>
            <end position="566"/>
        </location>
    </feature>
    <feature type="domain" description="DNA ligase OB-like" evidence="8">
        <location>
            <begin position="589"/>
            <end position="657"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01068"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF13649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF14743"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OBZ85584.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="666" mass="77175" checksum="2E43E9D19F029016" modified="2016-11-30" version="1">MVASTSLDVVPEDPTAYKTQEYWEERYQKEDSDTTFDWFKTYDELKPLLNEVIPNKDARILILGCGNSTLGEDMYNDGYKNIVNIDYSRTVIENMKKRCEDKPEMTWLEMDIRALKFDDASFDAIIDKGTMDALMCDRGDVWDPSEELINDVKGEVDEVQRTLKVGGVFIYITFGQPHFRKRHLQRDCWTINTKTMGDAFHYFFYTMQIEAIKELSKAVNSTSSTHEKRALLLKYPDTHDTLRRIYDPHLRHHVSAKVVSSYLMKNPTTTSEHIFEDLNQLLDALSSRQLTGHDAYSAIGTFFNAYCKTEEHKATFWHILDRNLKMGVSIRTIRHMLSKDTPVKNTQSTMKKNSNFHVALATSLSKKDLDFTSNNEDKWYASQKLDGVRCITFVTLDDSNHYNIQFYSRTGRPFSSLEKLRKEIEKRLSNIQCKDSFVLDGEVCAYNDADPTREDFLKALGQVRRLNTEMENPVYQVFDYICLDDFLKEKSDVLFSQRQKRLSDFIGQSSCSDLQHIKLVKQTLLRDLDHLNHLKQESARLGWEGLILRKDVAYEGKRTRNMLKVKEWEDAEYTVQSIETGLMRMPDTGEVKQVMTNVMIEHKGNIVSVGSGFSMQSRINFAQDPSKIIGKVITVRYFSEFFKDNGAISLRFPTIKAVYNEGKRDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NE64</accession>
    <name>A0A1C7NE64_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Meiotic recombination protein DMC1/LIM15</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">DMC1</name>
        <name evidence="13" type="ORF">A0J61_04543</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the RecA family. DMC1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000225">
        <property type="protein sequence ID" value="OBZ87403.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NE64"/>
    <dbReference type="FunCoup" id="A0A1C7NE64">
        <property type="interactions" value="214"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NE64"/>
    <dbReference type="InParanoid" id="A0A1C7NE64"/>
    <dbReference type="OrthoDB" id="10251254at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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        <property type="term" value="C:condensed nuclear chromosome"/>
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        <property type="term" value="F:DNA strand exchange activity"/>
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        <property type="term" value="P:chromosome organization involved in meiotic cell cycle"/>
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    <dbReference type="GO" id="GO:0000730">
        <property type="term" value="P:DNA recombinase assembly"/>
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        <property type="term" value="P:DNA strand invasion"/>
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        <property type="term" value="P:meiotic joint molecule formation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
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    <dbReference type="GO" id="GO:0006312">
        <property type="term" value="P:mitotic recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
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        <property type="entry name" value="DMC1"/>
        <property type="match status" value="1"/>
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        <property type="entry name" value="Meiotic recombination protein DMC1"/>
        <property type="match status" value="1"/>
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    <dbReference type="FunFam" id="1.10.150.20:FF:000032">
        <property type="entry name" value="meiotic recombination protein DMC1/LIM15 homolog"/>
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        <property type="entry name" value="5' to 3' exonuclease, C-terminal subdomain"/>
        <property type="match status" value="1"/>
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        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
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        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011940">
        <property type="entry name" value="Dmc1"/>
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    <dbReference type="InterPro" id="IPR016467">
        <property type="entry name" value="DNA_recomb/repair_RecA-like"/>
    </dbReference>
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        <property type="entry name" value="DNA_repair_Rad51/TF_NusA_a-hlx"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
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        <property type="entry name" value="Rad51_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020588">
        <property type="entry name" value="RecA_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020587">
        <property type="entry name" value="RecA_monomer-monomer_interface"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003301">
        <property type="entry name" value="PRK04301.1"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="recomb_DMC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22942:SF30">
        <property type="entry name" value="MEIOTIC RECOMBINATION PROTEIN DMC1_LIM15 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22942">
        <property type="entry name" value="RECA/RAD51/RADA DNA STRAND-PAIRING FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14520">
        <property type="entry name" value="HHH_5"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Rad51"/>
        <property type="match status" value="1"/>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
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    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47794">
        <property type="entry name" value="Rad51 N-terminal domain-like"/>
        <property type="match status" value="1"/>
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        <property type="entry name" value="RECA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50163">
        <property type="entry name" value="RECA_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-0469">Meiosis</keyword>
    <keyword evidence="3 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RecA family profile 1" evidence="11">
        <location>
            <begin position="111"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="domain" description="RecA family profile 2" evidence="12">
        <location>
            <begin position="291"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008897"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU003422"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50162"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="OBZ87403.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="354" mass="38823" checksum="754EDEC33BC10CC8" modified="2016-11-30" version="1">MPSRREESVLDEDVSVTQTQEIDQQPQEEEETLFYTEIDELQMHGIGVADIQKLKAAGICTVRGAQMMTKKALLKIKGLSETKVDKIKEAAIKSQGPAFVSAKEVALQRQKVVKISTGSQQLDTLLGGGIQTMSLTEVFGEFRTGKTQMAHTLCVQVQMPPESGGANGRAAYIDTEGTFRPDRIMSIADRFGADPDIVLDNIVVARAWNSDQQMELIAELAAHFAEQKGVYRLLVIDSIISLFRCDYSGRGELADRQQKLNQMLSRLTKISEEYNIAVFLTNQVSSDPGAGMTFVADPKKPVGGHVLAHASSTRIYLRKGRGEERVAKLFDSPDMPESEASYSISSGGIVDVSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NE86</accession>
    <name>A0A1C7NE86_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">DNA-directed RNA polymerase subunit</fullName>
            <ecNumber evidence="14">2.7.7.6</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="primary">rpa1</name>
        <name evidence="17" type="ORF">A0J61_04541</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Largest and catalytic core component of RNA polymerase I which synthesizes ribosomal RNA precursors. Forms the polymerase active center together with the second largest subunit. A single stranded DNA template strand of the promoter is positioned within the central active site cleft of Pol I. A bridging helix emanates from RPA1 and crosses the cleft near the catalytic site and is thought to promote translocation of Pol I by acting as a ratchet that moves the RNA-DNA hybrid through the active site by switching from straight to bent conformations at each step of nucleotide addition.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12 14">
            <text>RNA(n) + a ribonucleoside 5'-triphosphate = RNA(n+1) + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:21248"/>
            <dbReference type="Rhea" id="RHEA-COMP:14527"/>
            <dbReference type="Rhea" id="RHEA-COMP:17342"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61557"/>
            <dbReference type="ChEBI" id="CHEBI:140395"/>
            <dbReference type="EC" id="2.7.7.6"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="3">Component of the RNA polymerase I (Pol I) complex consisting of at least 13 subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 14">Belongs to the RNA polymerase beta' chain family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.6" evidence="14"/>
    <dbReference type="EMBL" id="LUGH01000225">
        <property type="protein sequence ID" value="OBZ87405.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="FunCoup" id="A0A1C7NE86">
        <property type="interactions" value="629"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NE86"/>
    <dbReference type="InParanoid" id="A0A1C7NE86"/>
    <dbReference type="OrthoDB" id="270392at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005736">
        <property type="term" value="C:RNA polymerase I complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003899">
        <property type="term" value="F:DNA-directed RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02735">
        <property type="entry name" value="RNAP_I_Rpa1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01435">
        <property type="entry name" value="RNAP_I_RPA1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.40.20:FF:000019">
        <property type="entry name" value="DNA-directed RNA polymerase II subunit RPB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.150.390:FF:000005">
        <property type="entry name" value="DNA-directed RNA polymerase subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.274.100:FF:000006">
        <property type="entry name" value="DNA-directed RNA polymerase subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1490.180:FF:000003">
        <property type="entry name" value="DNA-directed RNA polymerase subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="4.10.860.120:FF:000006">
        <property type="entry name" value="DNA-directed RNA polymerase subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.132.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.390">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.357.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.40.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.2850">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.180">
        <property type="entry name" value="RNA polymerase ii"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.860.120">
        <property type="entry name" value="RNA polymerase II, clamp domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.274.100">
        <property type="entry name" value="RNA polymerase Rpb1, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047107">
        <property type="entry name" value="DNA-dir_RNA_pol1_lsu_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015699">
        <property type="entry name" value="DNA-dir_RNA_pol1_lsu_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045867">
        <property type="entry name" value="DNA-dir_RpoC_beta_prime"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000722">
        <property type="entry name" value="RNA_pol_asu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006592">
        <property type="entry name" value="RNA_pol_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007080">
        <property type="entry name" value="RNA_pol_Rpb1_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007066">
        <property type="entry name" value="RNA_pol_Rpb1_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042102">
        <property type="entry name" value="RNA_pol_Rpb1_3_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007083">
        <property type="entry name" value="RNA_pol_Rpb1_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007081">
        <property type="entry name" value="RNA_pol_Rpb1_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044893">
        <property type="entry name" value="RNA_pol_Rpb1_clamp_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038120">
        <property type="entry name" value="Rpb1_funnel_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19376">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19376:SF11">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE I SUBUNIT RPA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04997">
        <property type="entry name" value="RNA_pol_Rpb1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00623">
        <property type="entry name" value="RNA_pol_Rpb1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04983">
        <property type="entry name" value="RNA_pol_Rpb1_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05000">
        <property type="entry name" value="RNA_pol_Rpb1_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04998">
        <property type="entry name" value="RNA_pol_Rpb1_5"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00663">
        <property type="entry name" value="RPOLA_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64484">
        <property type="entry name" value="beta and beta-prime subunits of DNA dependent RNA-polymerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 14 17" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="9" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 14" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="11" id="KW-0539">Nucleus</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10 14" id="KW-0804">Transcription</keyword>
    <keyword evidence="5 14" id="KW-0808">Transferase</keyword>
    <keyword evidence="8" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="RNA polymerase N-terminal" evidence="16">
        <location>
            <begin position="320"/>
            <end position="661"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="1339"/>
            <end position="1429"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="15">
        <location>
            <begin position="1369"/>
            <end position="1379"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="15">
        <location>
            <begin position="1381"/>
            <end position="1416"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00048552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00053996"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU004279"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="SMART" id="SM00663"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="OBZ87405.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="1648" mass="184923" checksum="CB1A276CA87E51FD" modified="2016-11-30" version="1">MNISVPIGTEVDSVSFSFYEPSEIRKISVKQIVNPVLFDTLGHPTKGGLYDPALGPYQKTQICATCSQDHYNCPGHYGHIEVPIPAYNPMFFDNLYAILRAKCVYCHHFRISRAVMKRFSGQLKLLQHGLIREAQALDEVYFDQKKVKKEKEDETLEDKMEEDSLLMSNAEEYIDYIDNFVKSSLADEEARRFAADNYKITVINEVRKKVMADFMRLCLHTKKCLNCQGISPPVRRDGAAKLFQLQLTKKEQAHMDRIKSNLGFEDEVKGFNANGQRFMTPYEVRKQVQALFEKEGDITTLLYGARDPRIPSFIKKATYHMFFIETLAVAPTRFRPPSVMGDKIFESPQNELLSGILKGSHLVRDLSDELQKVSDEEQSDKNKIERVRTNFVESIINLQHAVNSFIDSTKNPAQVAQGQTNPPGIRQALEKKEGLFRKHMMGKRVNYAARSVISPDPFIETSEIGIPPVFATKLTYPEPVTPHNFKEMRQAVINGPNKWPGATHVQNEDQSIDVLADLSIESRIALANSLLAPQSSTATQSGNNPYPTRTQTVNKKVLRHLRNGDMLLLNRQPTLHKPSIMAHKARILPGEKTIRMHYANCNTYNADFDGDEMNIHFPQNEIARAEASFIANTDNQYLVPTSGDPLRGLIQDSVDSGVWMSCRDTFFTREEYQQLLYGSLRPEVDGTGGGKIQMLPPTIWKPQPLWTGKQVISTILKNLTWGSAQLNMTSKSKVPARYWGPNAKEEEVVNIMEGELLHGILDKSQFGASAFGLVHSIYEIYGAEKAGMLLSILGRLFIKFIQSHGFTCRMDDLVLTKEGDQWRRDLLDDGKDLGNEAHMEFLGLTETAKSANSDVLAKEFKLRMNEVVRDDNKLAGLDNAMKAKVNKLTSSITTKCLPNGLFRPFPKNDMQMMTVSGAKGSNVNATQISCLLGQQELEGRRVPLMVSGRSLPSFRPFDTRPRAGGFVTGRFLTGIRPQEYYFHCMAGREGLIDTAVKTSRSGYLQRCLIKHLEGLRVHYDHTVRDSDGSVLQFHYGEDSLDVIKAKHINQFSFSAHNFEALSQKYNPKAALESLETKKGEEFAKKALKKPNKYDPALSVFNPGTHLGVVSERFAIAMKDYMEKNPDKMPFEKDTEPSKNTARYAGLTKSKFKALMNLKYLHSLVEPGEAVGLLAAQSVGEPSTQMTLNTFHFAGYGAANVTLGIPRLREIIMTAARKIKTPTMLLPLRPETSAKKASQFCKSASRLTLAQLVDDVSVTEKTTAKSAETNYRRSKTYSIRLNLFNESEYKEEYRVSANKIKEVLSSTFLRDLEELIRRDLKDTKKIDDISKAHKMADVADDDANENLGDAAAKDSYDSDADNEDDAKASRTSARNKQQATYDEADDDEMVVDEADKSLEDEEAEFEESVMAGEDDEDDKPKKKSSKNSEESIIQKSKYAKKFVFDDVNGSYCQIDMVFPADTKKILMVGLVEEACTRTVVHEIKGIQTCFEYVNPTENDTSKRLQTEGVNLRGMWAHSDLIDVNFIDTNDIAAILNTYGVEAARNAIIKEVGAVFGVYGIKVDRRHLTLIADYMTFEGGYKPFSRIGIGSNVAPFLKMSFESTCKFLTEATLHGDYDTLDSPSSRIVVGRVVEGGTGSFDILQPLTSEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NEL2</accession>
    <name>A0A1C7NEL2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">GrpE protein homolog</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">grpe</name>
        <name evidence="7" type="ORF">A0J61_04410</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 4">Mitochondrion matrix</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the GrpE family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000215">
        <property type="protein sequence ID" value="OBZ87545.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NEL2"/>
    <dbReference type="FunCoup" id="A0A1C7NEL2">
        <property type="interactions" value="219"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NEL2"/>
    <dbReference type="InParanoid" id="A0A1C7NEL2"/>
    <dbReference type="OrthoDB" id="201635at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001405">
        <property type="term" value="C:PAM complex, Tim23 associated import motor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000774">
        <property type="term" value="F:adenyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042803">
        <property type="term" value="F:protein homodimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051087">
        <property type="term" value="F:protein-folding chaperone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030150">
        <property type="term" value="P:protein import into mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042026">
        <property type="term" value="P:protein refolding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd00446">
        <property type="entry name" value="GrpE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.22.10:FF:000002">
        <property type="entry name" value="GrpE protein homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.20.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.22.10">
        <property type="entry name" value="Head domain of nucleotide exchange factor GrpE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01151">
        <property type="entry name" value="GrpE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000740">
        <property type="entry name" value="GrpE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013805">
        <property type="entry name" value="GrpE_CC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009012">
        <property type="entry name" value="GrpE_head"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21237">
        <property type="entry name" value="GRPE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21237:SF23">
        <property type="entry name" value="GRPE PROTEIN HOMOLOG, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01025">
        <property type="entry name" value="GrpE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00773">
        <property type="entry name" value="GRPEPROTEIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF58014">
        <property type="entry name" value="Coiled-coil domain of nucleotide exchange factor GrpE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51064">
        <property type="entry name" value="Head domain of nucleotide exchange factor GrpE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01071">
        <property type="entry name" value="GRPE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0143">Chaperone</keyword>
    <keyword evidence="4" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="34"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="40"/>
            <end position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004305"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU004478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OBZ87545.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="231" mass="25974" checksum="75274278B07B44B6" modified="2016-11-30" version="1">MLSANLFRNAAAMSVKRSSMMAASIRPTSFGLRTFATENNDTKDEKKEEQATEETKVELSEEVKKMLAEKDKQIAEIKDAYLRCLADQENIRERSRKEIETTKEFAIQKFAKDLLDTVDILNMALTAVPDELRQKTDNLTADVNTVFNQLTNLYTGVSMTESELVKALKRHGVERENPEGEVFDPNRHQALFQAPMPGKEAGTIFVVQKMGYSLKGRVLRPAQVGVVAESQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NEN8</accession>
    <name>A0A1C7NEN8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">C3H1-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">A0J61_04533</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000224">
        <property type="protein sequence ID" value="OBZ87420.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NEN8"/>
    <dbReference type="InParanoid" id="A0A1C7NEN8"/>
    <dbReference type="OrthoDB" id="7459479at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.1000.10">
        <property type="entry name" value="Zinc finger, CCCH-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000571">
        <property type="entry name" value="Znf_CCCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036855">
        <property type="entry name" value="Znf_CCCH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36971:SF3">
        <property type="entry name" value="C3H1-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36971">
        <property type="entry name" value="UNNAMED PRODUCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90229">
        <property type="entry name" value="CCCH zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50103">
        <property type="entry name" value="ZF_C3H1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C3H1-type" evidence="5">
        <location>
            <begin position="128"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="4">
        <location>
            <begin position="128"/>
            <end position="155"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OBZ87420.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="405" mass="46564" checksum="10C6C11E5F057811" modified="2016-11-30" version="1">MISITHTINGQIRHRRKLTKLIFFVDIQESTGLKSQVFFRKDDNSLDDQQFQEAFRSCKPGQTVEIQVGLPLDPSERVGKPFPVWQSDCPVQVIEPYTARQAFIQDRALGSTDILTDIRLTDGTRKHKSQLVCKYWINKNKCIQGDNCLFQHPTGDAFDTSRSLWLDQKFQSRKEINHDPNDPHKDKKPHSVRAIVFADWIQKTFGNIIGQGIVLDVAGGKGELAMFLSRGFGIPSVVVEPNERNRPSYWYTRLRRLLYRFEIGDLDQPDWKRKDIQIDMNQWPYSTTPDYLHTFLDSQFLNEHTELLSKVSLFIGLHADQATVPIVEAALKAGKAFAVVPCCVFSHENRERRLQSGQLVTTTEQQIQYICELKEPGEIKTAYLDFEGKNVVVYWLPSHPTLSIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NEV6</accession>
    <name>A0A1C7NEV6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="19">Myosin-1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="19" type="primary">MYO1</name>
        <name evidence="19" type="ORF">A0J61_04314</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="19 20" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19 20">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
            <location evidence="1">Actin patch</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 14">Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="19">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000208">
        <property type="protein sequence ID" value="OBZ87642.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NEV6"/>
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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        <property type="term" value="C:actin cortical patch"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
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    <dbReference type="GO" id="GO:0051285">
        <property type="term" value="C:cell cortex of cell tip"/>
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        <property type="project" value="EnsemblFungi"/>
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    <dbReference type="GO" id="GO:0043332">
        <property type="term" value="C:mating projection tip"/>
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        <property type="term" value="C:medial cortex"/>
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        <property type="term" value="C:myosin I complex"/>
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        <property type="term" value="C:plasma membrane raft"/>
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        <property type="term" value="F:Arp2/3 complex binding"/>
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    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
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        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
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        <property type="project" value="UniProtKB-KW"/>
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    <dbReference type="GO" id="GO:0000146">
        <property type="term" value="F:microfilament motor activity"/>
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    <dbReference type="GO" id="GO:0000147">
        <property type="term" value="P:actin cortical patch assembly"/>
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        <property type="project" value="EnsemblFungi"/>
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    <dbReference type="GO" id="GO:0051666">
        <property type="term" value="P:actin cortical patch localization"/>
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    </dbReference>
    <dbReference type="GO" id="GO:0007015">
        <property type="term" value="P:actin filament organization"/>
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    </dbReference>
    <dbReference type="GO" id="GO:0006897">
        <property type="term" value="P:endocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000281">
        <property type="term" value="P:mitotic cytokinesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd01378">
        <property type="entry name" value="MYSc_Myo1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd11858">
        <property type="entry name" value="SH3_Myosin-I_fungi"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.820:FF:000001">
        <property type="entry name" value="Myosin heavy chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.120.720:FF:000015">
        <property type="entry name" value="Myosin I"/>
        <property type="match status" value="1"/>
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        <property type="entry name" value="Unconventional Myosin IB"/>
        <property type="match status" value="1"/>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.4820">
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Kinesin motor domain"/>
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    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.720">
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Fungal_myosin-I_SH3"/>
    </dbReference>
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        <property type="entry name" value="Kinesin_motor_dom_sf"/>
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        <property type="entry name" value="Myosin_head_motor_dom-like"/>
    </dbReference>
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        <property type="entry name" value="Myosin_TH1"/>
    </dbReference>
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        <property type="entry name" value="MYSc_Myo1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036028">
        <property type="entry name" value="SH3-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001452">
        <property type="entry name" value="SH3_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13140">
        <property type="entry name" value="MYOSIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13140:SF837">
        <property type="entry name" value="MYOSIN-3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00063">
        <property type="entry name" value="Myosin_head"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06017">
        <property type="entry name" value="Myosin_TH1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00018">
        <property type="entry name" value="SH3_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00193">
        <property type="entry name" value="MYOSINHEAVY"/>
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        <property type="entry name" value="MYSc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00326">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SH3-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51456">
        <property type="entry name" value="MYOSIN_MOTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="TH1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12 14" id="KW-0009">Actin-binding</keyword>
    <keyword evidence="9 14" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="11 14" id="KW-0505">Motor protein</keyword>
    <keyword evidence="10 14" id="KW-0518">Myosin</keyword>
    <keyword evidence="7 14" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 13" id="KW-0728">SH3 domain</keyword>
    <feature type="domain" description="Myosin motor" evidence="17">
        <location>
            <begin position="34"/>
            <end position="715"/>
        </location>
    </feature>
    <feature type="domain" description="TH1" evidence="18">
        <location>
            <begin position="773"/>
            <end position="963"/>
        </location>
    </feature>
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        <location>
            <begin position="1035"/>
            <end position="1094"/>
        </location>
    </feature>
    <feature type="region of interest" description="Actin-binding" evidence="14">
        <location>
            <begin position="588"/>
            <end position="610"/>
        </location>
    </feature>
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        <location>
            <begin position="961"/>
            <end position="1037"/>
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    </feature>
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        <location>
            <begin position="1092"/>
            <end position="1252"/>
        </location>
    </feature>
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        <location>
            <begin position="996"/>
            <end position="1008"/>
        </location>
    </feature>
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        <location>
            <begin position="1014"/>
            <end position="1033"/>
        </location>
    </feature>
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            <end position="1107"/>
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            <begin position="1108"/>
            <end position="1149"/>
        </location>
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            <begin position="1168"/>
            <end position="1177"/>
        </location>
    </feature>
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            <begin position="1178"/>
            <end position="1188"/>
        </location>
    </feature>
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        <location>
            <begin position="1216"/>
            <end position="1233"/>
        </location>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <begin position="127"/>
            <end position="134"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004134"/>
        </source>
    </evidence>
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            <dbReference type="ARBA" id="ARBA00008314"/>
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            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
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        </source>
    </evidence>
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        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS51456"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS51757"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="OBZ87642.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="1252" mass="139259" checksum="A665788FED8A4D6D" modified="2016-11-30" version="1">MAKKLLGKKGEKKVIKANRPARADWKEGVKKKQVGVSDMTLLTKITNEAINENLQKRWQNAEIYTYIGHVLISVNPFRDLGIYTDDVLNSYKGKNLLEMPPHVFAIAEASYHHMNSYKENQCIIISGESGAGKTEAAKRIMQYIAAVSGDGQNSSIKEIKEMVLATNPLLESFGCAKTLRNDNSSRHGKYLEIQFNAQGEPVGAIITNYLLEKNRVVGQIDNERNFHIFYQMTKAASPEYQQSFGLQGPESFLYTSRSGCLDVAGIDDVQDFQATINAMNVIGLEQYEQDEIFKMLAIILWLGNVVFVENDEGYAAISDADVANFIAYLMEVDAEALTKALTSRVMETARGGRRGSVYEVPLNIVQATAVRDALSKAIYERLFEWIVTRVNVSLQARTAHQFTIGVLDIYGFEIFEENSFEQLCINYVNEKLQQIFIELTLKAEQEEYVREQIQWTPIKFFNNKIVCDLIEEKRPPGLFAALNDACATAHADSSAADNSFVQRLGFLSQNAHFESRGSKFLIRHYAGDVLYNVENMTDKNKDSLSKDLLNLCTGSSNQFIASTLFPERIDPNSKKRPPTASDKIKQSCNTLVSKLMQCHPSYIRTIKSNDNRSPSEFDEKRVLHQIQYLGLCENIRVRRAGFAYRTTFEKFVERFYLLCPTTGYAGEYIWNRDAQSGALEILKHNNIPAEEWQLGTTKVFIRHPETIFALENLRDKYWHNMATRIQRAWRAYVRYKIECAKKVQRFWRQNKYNIGYLQLREYGHQILAGQKERRRYSLVSMRRFTGDYLDIKQGSGLSTMIRNAISLKPGEDVVFSMRGSTLVPRAMRSSVPSPRSFVLTNQNLHIVVATKNGKVLSMVDEKVISLNVINGISVSTYQDDWVVLHIDSSPDGDTILSCVFKTELLAHMLQQTGGRIKVSVTPQIQYKKKGGKAVTMKFVKDETAKGDGVYKSHVVKIASGCPASSQSDPACPVKPRATKPTTNRAPPRKSNPVRNTTRPIPSSTPSSTANRSVPAPPSSSSSPPPPPPPPPASAPTLPQYKAIYPFQSQQAGEIAFEKDDILEIVEKDDNGWWLARKNGVEGWVPHNYLEEYVPPPAARSTPPPPPTRRAAPSIPSAAATPTQNKPVIPAAPVAPTNNNNNSSASNVPAWKQELEARKLAAANGSNGGSPVPAARRAPPAPGPKPMVPAKPSGMTKPAIPSRPGASAPTPAPRAPPRNANGTPSNAAASLADALRARRQQAPSHHEDDDDEW</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NEY2</accession>
    <name>A0A1C7NEY2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Pore membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">POM33</name>
        <name evidence="7" type="ORF">A0J61_04839</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the PER33/POM33 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000246">
        <property type="protein sequence ID" value="OBZ87106.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NEY2"/>
    <dbReference type="STRING" id="101091.A0A1C7NEY2"/>
    <dbReference type="InParanoid" id="A0A1C7NEY2"/>
    <dbReference type="OrthoDB" id="5581259at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071786">
        <property type="term" value="P:endoplasmic reticulum tubular network organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061024">
        <property type="term" value="P:membrane organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051645">
        <property type="entry name" value="PER33/POM33_regulator"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005344">
        <property type="entry name" value="TMEM33/Pom33"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12703">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 33"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12703:SF4">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 33"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03661">
        <property type="entry name" value="TMEM33_Pom33"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="37"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="75"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="140"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007322"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OBZ87106.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="221" mass="25931" checksum="22BB0B29A906D6EB" modified="2016-11-30" version="1" fragment="single">QGQFYWWLGHIFVLFNGLVYFSSILSFHTNPLFYKRAFASVFVSYSTVLYHIISTKNPTFKMLLSNQNMHYLIMAFYWYSSTPIAVTLVPFFLSSLVHCIAYIQSELISRLPDTSLLAKDQLSSYLQQWIQRHYKSVKQWIAYTEVVFIPAYLIIHVILWRVSILALIVYSYFLQSRYTQSTEIQATVHQTVDYLDSRLLNKHQPALITNVYSAIKQLVVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NEZ3</accession>
    <name>A0A1C7NEZ3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_04828</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000244">
        <property type="protein sequence ID" value="OBZ87126.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NEZ3"/>
    <dbReference type="STRING" id="101091.A0A1C7NEZ3"/>
    <dbReference type="InParanoid" id="A0A1C7NEZ3"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="55"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="518"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ87126.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="518" mass="53024" checksum="040C65973D747B0D" modified="2016-11-30" version="1" fragment="single">MRKIYADPMLNIRSLKGNPRKDIAIKVLILLKKTLQLRFSKAPYTFLLPMRTTSIFFAIFLVQLGGALGAVTLPLGKREVDSDVYQEEEFLPHIDRQLIGPLLGTTTVTATVGATATVTTTVRLQPVTVTTTTLSNPLTVTVPTTVNVPVLTTVSVTIPTTVPFPTTVSVPVPTLVSVTVPTVISITVPTTVTIPVPTTVSVPVPTLVSVTVPTLVTVPVPTTISVPVLTTINVPVISTLSVPVPTTLTIPVPTTISVPSFITVPTTVNVPSFITVNLPTTVAGPPVTITAPAICPTLPIPTPTTVTLPPITLPTPQITCPTLPIPGLPLPPVTVTSFILPPAVSSLSSLLPALNSALPALSSAIPPLNTAIPNLNNVIPSLTSVISRISVVLPSVNAPGVLPTLTNIASDLQNVLPGLYSAVPQLAGVVPNLSGALPVITSVLPQLPKVANDLSQAASNIAAIGAVPSNVASLLSSLASLPTGLPGFPGLPTDLPGLLGALAGLPTGLPVLPGLPTD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NF15</accession>
    <name>A0A1C7NF15_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Chitinase A1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">chiA1_0</name>
        <name evidence="5" type="ORF">A0J61_04395</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000214">
        <property type="protein sequence ID" value="OBZ87560.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NF15"/>
    <dbReference type="STRING" id="101091.A0A1C7NF15"/>
    <dbReference type="InParanoid" id="A0A1C7NF15"/>
    <dbReference type="OrthoDB" id="76388at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008061">
        <property type="term" value="F:chitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004568">
        <property type="term" value="F:chitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006032">
        <property type="term" value="P:chitin catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd12215">
        <property type="entry name" value="ChiC_BD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.50.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.10.20">
        <property type="entry name" value="Carbohydrate-binding module superfamily 5/12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003610">
        <property type="entry name" value="CBM5/12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036573">
        <property type="entry name" value="CBM_sf_5/12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011583">
        <property type="entry name" value="Chitinase_II/V-like_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029070">
        <property type="entry name" value="Chitinase_insertion_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001223">
        <property type="entry name" value="Glyco_hydro18_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050314">
        <property type="entry name" value="Glycosyl_Hydrlase_18"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11177">
        <property type="entry name" value="CHITINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11177:SF392">
        <property type="entry name" value="HAP41P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02839">
        <property type="entry name" value="CBM_5_12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00704">
        <property type="entry name" value="Glyco_hydro_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00495">
        <property type="entry name" value="ChtBD3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00636">
        <property type="entry name" value="Glyco_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51055">
        <property type="entry name" value="Carbohydrate binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54556">
        <property type="entry name" value="Chitinase insertion domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51910">
        <property type="entry name" value="GH18_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GH18" evidence="4">
        <location>
            <begin position="38"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="421"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="431"/>
            <end position="467"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OBZ87560.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="521" mass="56004" checksum="11ECEF0316BCD6E4" modified="2016-11-30" version="1">MKINAFLISVITTAYLCLLDGITASPLRLQARAGRSDKVIVGYFPNWLYGRYLPSKIDFKRYTHINYAFAIQNSGGTPIWQDTGVFDDYVQYGFPKLISLAHQAGTKVLISVGGWSGSTGFSTMAASASSRKSFVQWNIDFIKKFNTDGVDIDWEYPNSVGAGCNAVSDQDVDNFNLLIKELREALDSNFPNGHKEISIAVHITPWGGATKSDDVSGFVPYVDRFHVMAFDVNGAWNSTSGPNAPFRAEPGKGYSVGFAQGIEAWNAAGVPYNKLVGGIPFYGRAQTLTVSSNPTTQYNPAVSPNPPLGDSLDGPWTNPYCSKDSSQASGVWRWANMRSSGLLSSPTTAASPWIRHFDDITQTPWLYNPTNKQFISYDDPISLGVKTKYALDKGLAGLFVWSIEQDNGELLDAISPMIGGNSPPSAITSGAPSATNTPSQTSTQSATASVPPTSSSTTTNGSPTGTAGCDSANTWSSGTVYTSGSLATYQGKLYKAQWWTQGETPSANGPSWSVWSLVKTC</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NF61</accession>
    <name>A0A1C7NF61_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Fizzy-related protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">Fzr1</name>
        <name evidence="8" type="ORF">A0J61_04209</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the WD repeat CDC20/Fizzy family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000200">
        <property type="protein sequence ID" value="OBZ87743.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NF61"/>
    <dbReference type="FunCoup" id="A0A1C7NF61">
        <property type="interactions" value="273"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NF61"/>
    <dbReference type="InParanoid" id="A0A1C7NF61"/>
    <dbReference type="OrthoDB" id="10263272at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005680">
        <property type="term" value="C:anaphase-promoting complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010997">
        <property type="term" value="F:anaphase-promoting complex binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990757">
        <property type="term" value="F:ubiquitin ligase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031145">
        <property type="term" value="P:anaphase-promoting complex-dependent catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1905786">
        <property type="term" value="P:positive regulation of anaphase-promoting complex-dependent catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033010">
        <property type="entry name" value="Cdc20/Fizzy"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056150">
        <property type="entry name" value="WD40_CDC20-Fz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19918">
        <property type="entry name" value="CELL DIVISION CYCLE 20 CDC20 FIZZY -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19918:SF1">
        <property type="entry name" value="FIZZY-RELATED PROTEIN HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24807">
        <property type="entry name" value="WD40_CDC20-Fz"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 5" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="CDC20/Fizzy WD40" evidence="7">
        <location>
            <begin position="215"/>
            <end position="508"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="341"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="383"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="477"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="152"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="14"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="26"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006445"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF24807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OBZ87743.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="530" mass="59332" checksum="72BDE6426047849E" modified="2016-11-30" version="1">MSNNYKRKLRSYKPNKETQVEVKKEEDEETAKEEVEEESRQLPQTPSPVDDIQPFFPPSPFGRKRQQPAGDRFIPSRERDIVRDFQVHSDPNKRYSTDLSTEPVLSESSRRFHAFFRAEILNDPAAADEYISPERNTQRILYYQPNSSSSSVYPAVGHSDTSEATAESLGVEPSDSPTPHAPRFHTSVISEAGRRILSSTSHLERPINQTPIKTLDAPNLQDDFYLNLIDWGTNDFVAVGLNHAVYLWDAGTSRVTKLHEFVDTVTSVNWSQASSLLAIGTSSGHSFLYDTVTTRCIRAWHNHVSRIGTIAWRSNILSTGGRDRKIYHHDVRSPNAFFRKLSGHRHEVCGLKWNPEGTMLASGGNDNKLLVWDSHQDKVSHCFSEHQAAVKAISWSPHKRGILASGGGTADMTIKLWNTISGQLNASYHVGSQVCNLLWSKKTDEIVSTHGYSQDGAASSNSVILWKADKMKKLASLSGHNSRVLYMALSHDGSTVVTGAGDETIKFWDLFSLVKKTKPIETDERKGCLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NFC9</accession>
    <name>A0A1C7NFC9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_04480</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000220">
        <property type="protein sequence ID" value="OBZ87469.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NFC9"/>
    <dbReference type="InParanoid" id="A0A1C7NFC9"/>
    <dbReference type="OrthoDB" id="2289193at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ87469.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="62" mass="7318" checksum="73BBA255D9A24548" modified="2016-11-30" version="1">MLQQEYTVNLYDIVESLTKLFGNFNSKETSIHSFIETECNLLSVRATSRSSERNFKDELRQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NG09</accession>
    <name>A0A1C7NG09_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Phosphotransferase</fullName>
            <ecNumber evidence="6">2.7.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">hxk1_0</name>
        <name evidence="9" type="ORF">A0J61_05658</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the hexokinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.-" evidence="6"/>
    <dbReference type="EMBL" id="LUGH01000312">
        <property type="protein sequence ID" value="OBZ86294.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NG09"/>
    <dbReference type="STRING" id="101091.A0A1C7NG09"/>
    <dbReference type="InParanoid" id="A0A1C7NG09"/>
    <dbReference type="OrthoDB" id="419537at2759"/>
    <dbReference type="UniPathway" id="UPA00109">
        <property type="reaction ID" value="UER00180"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005536">
        <property type="term" value="F:D-glucose binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008865">
        <property type="term" value="F:fructokinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004340">
        <property type="term" value="F:glucokinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006006">
        <property type="term" value="P:glucose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006096">
        <property type="term" value="P:glycolytic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001678">
        <property type="term" value="P:intracellular glucose homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.367.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001312">
        <property type="entry name" value="Hexokinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022673">
        <property type="entry name" value="Hexokinase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022672">
        <property type="entry name" value="Hexokinase_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19443:SF30">
        <property type="entry name" value="GLUCOKINASE-1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19443">
        <property type="entry name" value="HEXOKINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00349">
        <property type="entry name" value="Hexokinase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03727">
        <property type="entry name" value="Hexokinase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00475">
        <property type="entry name" value="HEXOKINASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51748">
        <property type="entry name" value="HEXOKINASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="4 6 9" id="KW-0418">Kinase</keyword>
    <keyword evidence="3 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Hexokinase N-terminal" evidence="7">
        <location>
            <begin position="23"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="domain" description="Hexokinase C-terminal" evidence="8">
        <location>
            <begin position="225"/>
            <end position="468"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU362007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00349"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF03727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OBZ86294.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="479" mass="53236" checksum="658BC6A17E9D546D" modified="2016-11-30" version="1">MSQRQSVPLVELKHSTPPQVEAVKELEQLFCLDKATLLNVVGSFRHELVAGLADDRSSDLNMIPTYVTGYPTGDEKGTYLALEIAGMDIYACQVKLKGDNGKLAINQYQYKIPQNLASGEDFAVLIDYVVECISDFLMRVGTQDLFVYPMAVSFGFAIKQTRLDTGRILSLGYGFSYPNGVGIDIVELMHERIQFKGLPIKIVAIANDSVCTLLAHAYQHPATRLGIVHSLGTNCAYYEPVKNVTKLRDHSVTRNTDMIMNTEWCNFGSSRRTLPCTWFDRKLARESINPQFHVFEKMTTGIFLGELVRNIIIYLVDRDILFRGESSEILNTMHSFDTSYMYVCEADDTDTLEDTRIVLEDMLDLSRTSIGDREVVKKICELVGARAAALVGASIAAIVQHMTEKGIGMTEEGYAISISGSIYEDYPSFHPRVCKTLKDLIPEKLAGKLSVGVVKHSRIVGAAIVAMMAEKIASNTTQH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NGT3</accession>
    <name>A0A1C7NGT3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_03714</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000165">
        <property type="protein sequence ID" value="OBZ88245.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NGT3"/>
    <dbReference type="InParanoid" id="A0A1C7NGT3"/>
    <dbReference type="OrthoDB" id="2289096at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="47"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="248"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="47"/>
            <end position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ88245.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="326" mass="38004" checksum="2B2205A23EC1ACA3" modified="2016-11-30" version="1">MVTVLEPKGAKTTSYEICSDDDSVTEIKAKPRKRKTGTQALVEFLNTTSPKEFQKSTQHSKRSPSFFLRQKPKSQNKCVVNLDNVQLVYRKNHIEIITRPTTDTSSSYIKEDFVRQQPPLRFQAIYSQQQQQQQQQQQQQQQQQQQQQDHCLIERVGTTGEHDIIQEGLKQRLALYEQLNLESPGDPLSKIIAHEYLDTRKTTEYPKSFQKNARHVQIQTMPLDVMSLENTFVTLENQDNKEDADGSTKSIKKELQEARTKNARLEAALRETHDQLELISGVAYQRLKQMWQEKMMWEQACIQVKEQCWQDHQQHIFAGIDLSDNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NGX0</accession>
    <name>A0A1C7NGX0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">UDP-glucuronosyltransferase 2B9</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">UGT2B9_0</name>
        <name evidence="6" type="ORF">A0J61_03693</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the UDP-glycosyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000164">
        <property type="protein sequence ID" value="OBZ88258.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NGX0"/>
    <dbReference type="STRING" id="101091.A0A1C7NGX0"/>
    <dbReference type="InParanoid" id="A0A1C7NGX0"/>
    <dbReference type="OrthoDB" id="5835829at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008194">
        <property type="term" value="F:UDP-glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03784">
        <property type="entry name" value="GT1_Gtf-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2000">
        <property type="entry name" value="Glycogen Phosphorylase B"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050271">
        <property type="entry name" value="UDP-glycosyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002213">
        <property type="entry name" value="UDP_glucos_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035595">
        <property type="entry name" value="UDP_glycos_trans_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48043">
        <property type="entry name" value="EG:EG0003.4 PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48043:SF145">
        <property type="entry name" value="FI06409P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00201">
        <property type="entry name" value="UDPGT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53756">
        <property type="entry name" value="UDP-Glycosyltransferase/glycogen phosphorylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00375">
        <property type="entry name" value="UDPGT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 3" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <keyword evidence="2 3 6" id="KW-0808">Transferase</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008889695" evidence="5">
        <location>
            <begin position="23"/>
            <end position="552"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="513"/>
            <end position="539"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003718"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OBZ88258.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="552" mass="61971" checksum="3057BDC24AD4A044" modified="2016-11-30" version="1">MKLKSISLFSLTASLLLSFGQANDLETTYYQDQGFKKVAFFAAMGGSSHYNWVLNICDELGSRGHNTTFLTAEKVTKFGKPFKHVQTVPIVPDIKYDAKNVANSETIRSIHPGKLISFVFELNVKDYKKSYLAIRDYLAENEVDLALCDHFAGSCVDAAKAVGIPYIITTTPVSVDGASAPYITVDPDYGSQPTTEFQSLFSRFYDRYVSSFIFHKHLSPVLKKQMQAKKELGLPAKMEDQSETWKDSLILVNNAFGLLPARPLGPLVELIGPIMNKQYPPLTDSFKTFLDSHQRVAYIAFGQTATPSPKDATTILLSLLEGLEQGVLDGFIWSTVNSDDLFPETVKTKSGKVYHTQDIFAGTYPEIRMVTWSPQMSLLLHPSVRLFVSHAGFGSISESIFAGKPLLLFPFFGDQPNNARWLEQNKLGMAFAYDTPSLEITKKMKLLVEDKDSVYSEHMKRMKAHVQIRSRHSVIRGADLVEEVLYTHRDGVVEHRVSADRRMSYIKAHNLDLYALLSLVVTSILSVFGFVAFKLYALAQPYLRQHNKLKTQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NH85</accession>
    <name>A0A1C7NH85_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Putative cytosolic iron-sulfur protein assembly protein CIAO1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">A0J61_03842</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000174">
        <property type="protein sequence ID" value="OBZ88119.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NH85"/>
    <dbReference type="FunCoup" id="A0A1C7NH85">
        <property type="interactions" value="248"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NH85"/>
    <dbReference type="InParanoid" id="A0A1C7NH85"/>
    <dbReference type="OrthoDB" id="284782at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097361">
        <property type="term" value="C:cytosolic [4Fe-4S] assembly targeting complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016226">
        <property type="term" value="P:iron-sulfur cluster assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002098">
        <property type="term" value="P:tRNA wobble uridine modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.10:FF:000136">
        <property type="entry name" value="Probable cytosolic iron-sulfur protein assembly protein CIAO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03037">
        <property type="entry name" value="ciao1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028608">
        <property type="entry name" value="CIAO1/Cia1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19920:SF0">
        <property type="entry name" value="CYTOSOLIC IRON-SULFUR PROTEIN ASSEMBLY PROTEIN CIAO1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19920">
        <property type="entry name" value="WD40 PROTEIN CIAO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="5"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="6"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="55"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="101"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="146"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="190"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OBZ88119.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="339" mass="38516" checksum="9C27ED2E408EBFFC" modified="2016-11-30" version="1" fragment="single">FFFVSSTGHQDRVWQAAWHPTKTLLATCSGDKTVRLWQPASHDNFSEWHCVETLEGAHKRTIRSVAWSPTGNEIATASFDATTGIWENDPRENDWECVATLEGHENEIKSVSWSSTGALLATCSRDKSVWIWEVEQDNDFECLSVLQEHTQDVKMVTWHPKLEILASASYDDTIKIWKEDDDDWYCADTLQGHTSTVWSLDFNAEGDQIVSASDDQTLRIWKMYKANNPQGVMTPNGDAAWKSICTLSGFHERCIYSVSWSKVNDRIASVSGDNSIRIFEKDMEREDPDAPVYKNLTTTTDAHGVYDINGVAWFPTEKHADWLSTVGDDGLVRIWRLVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NHG0</accession>
    <name>A0A1C7NHG0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Maintenance of mitochondrial morphology protein 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="primary">prp40</name>
        <name evidence="11" type="synonym">MMM1</name>
        <name evidence="17" type="ORF">A0J61_03485</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria. The MDM12-MMM1 subcomplex functions in the major beta-barrel assembly pathway that is responsible for biogenesis of all outer membrane beta-barrel proteins, and acts in a late step after the SAM complex. The MDM10-MDM12-MMM1 subcomplex further acts in the TOM40-specific pathway after the action of the MDM12-MMM1 complex. Essential for establishing and maintaining the structure of mitochondria and maintenance of mtDNA nucleoids.</text>
    </comment>
    <comment type="subunit">
        <text evidence="11">Homodimer. Component of the ER-mitochondria encounter structure (ERMES) or MDM complex, composed of MMM1, MDM10, MDM12 and MDM34. A MMM1 homodimer associates with one molecule of MDM12 on each side in a pairwise head-to-tail manner, and the SMP-LTD domains of MMM1 and MDM12 generate a continuous hydrophobic tunnel for phospholipid trafficking.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="11">Endoplasmic reticulum membrane</location>
            <topology evidence="11">Single-pass type I membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
        <text evidence="11">The ERMES/MDM complex localizes to a few discrete foci (around 10 per single cell), that represent mitochondria-endoplasmic reticulum junctions. These foci are often found next to mtDNA nucleoids.</text>
    </comment>
    <comment type="similarity">
        <text evidence="11">Belongs to the MMM1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000151">
        <property type="protein sequence ID" value="OBZ88465.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NHG0"/>
    <dbReference type="FunCoup" id="A0A1C7NHG0">
        <property type="interactions" value="888"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NHG0"/>
    <dbReference type="InParanoid" id="A0A1C7NHG0"/>
    <dbReference type="OrthoDB" id="187617at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032865">
        <property type="term" value="C:ERMES complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005685">
        <property type="term" value="C:U1 snRNP"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071004">
        <property type="term" value="C:U2-type prespliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008289">
        <property type="term" value="F:lipid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006869">
        <property type="term" value="P:lipid transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045292">
        <property type="term" value="P:mRNA cis splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045040">
        <property type="term" value="P:protein insertion into mitochondrial outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd21671">
        <property type="entry name" value="SMP_Mmm1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00201">
        <property type="entry name" value="WW"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.440:FF:000013">
        <property type="entry name" value="pre-mRNA-processing protein 40A isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.70.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.440">
        <property type="entry name" value="FF domain"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03103">
        <property type="entry name" value="Mmm1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002713">
        <property type="entry name" value="FF_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036517">
        <property type="entry name" value="FF_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027537">
        <property type="entry name" value="Mmm1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019411">
        <property type="entry name" value="MMM1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039726">
        <property type="entry name" value="Prp40-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031468">
        <property type="entry name" value="SMP_LBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001202">
        <property type="entry name" value="WW_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036020">
        <property type="entry name" value="WW_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11864">
        <property type="entry name" value="PRE-MRNA-PROCESSING PROTEIN PRP40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11864:SF0">
        <property type="entry name" value="PRP40 PRE-MRNA PROCESSING FACTOR 40 HOMOLOG A (YEAST)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01846">
        <property type="entry name" value="FF"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25432">
        <property type="entry name" value="FF_PRPF40A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10296">
        <property type="entry name" value="MMM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00397">
        <property type="entry name" value="WW"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00441">
        <property type="entry name" value="FF"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SMART" id="SM00456">
        <property type="entry name" value="WW"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81698">
        <property type="entry name" value="FF domain"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51045">
        <property type="entry name" value="WW domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51676">
        <property type="entry name" value="FF"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51847">
        <property type="entry name" value="SMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01159">
        <property type="entry name" value="WW_DOMAIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50020">
        <property type="entry name" value="WW_DOMAIN_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="6" id="KW-0445">Lipid transport</keyword>
    <keyword evidence="7" id="KW-0446">Lipid-binding</keyword>
    <keyword evidence="8 11 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="9" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="11 13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="11 13" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="topological domain" description="Lumenal" evidence="11">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="30"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="topological domain" description="Cytoplasmic" evidence="11">
        <location>
            <begin position="55"/>
            <end position="983"/>
        </location>
    </feature>
    <feature type="domain" description="SMP-LTD" evidence="16">
        <location>
            <begin position="100"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="domain" description="WW" evidence="14">
        <location>
            <begin position="354"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="domain" description="WW" evidence="14">
        <location>
            <begin position="399"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="domain" description="FF" evidence="15">
        <location>
            <begin position="495"/>
            <end position="549"/>
        </location>
    </feature>
    <feature type="domain" description="FF" evidence="15">
        <location>
            <begin position="707"/>
            <end position="768"/>
        </location>
    </feature>
    <feature type="domain" description="FF" evidence="15">
        <location>
            <begin position="839"/>
            <end position="901"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="905"/>
            <end position="983"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="915"/>
            <end position="926"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="12">
        <location>
            <begin position="965"/>
            <end position="976"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS51847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="OBZ88465.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="983" mass="115336" checksum="178E81C80D78AC3E" modified="2016-11-30" version="1">MENSTNESFTPQLLKLITDISCSRRSTLSFLSGFVLGQISVILIVALVLRYLFTEDVRNVKKRYIPSRLSSTPPSRLNASIPLPKDHITSKTYYDMIHHPPESTDWLNVLLAQVILQYREDAKINDRLILAMDEILNGGVKPNFIGHIHVTELNLGEEFPIFSNARIRRSDEVGSMRAEIDFEYNDQATLGIETQLILNWPVQAFAALPISLVLSVVRFSGTLTIELISPPATTTQPEIALDRYIAISSHSDFVLDLKVQSLIGSKTKLEDIPKLRDLIQTKLRNVYIDKLVYPTFVKIKVPSMWKETPPMPPTSDLNPLQPTAAEKIEEFVQEYAPPQPGPFPGMPPATTWGMPAMPVWKEHQTPEGRKYWYNNATGKSTWEKPDELLTPEERVLKASPWKEYTTPEGKKYYSNTKTKETVWEVPAELKEQLEQAKQQAATLLETPSEPPSMPIQPHPIQHHPIHHYPNQSIRPTMPITSQLIAQSPAPEYATKEEAEKAFFGLLKETGVKSDWTWEQAMRAIITKPLYRALKTTVERKAAFHTWAEAEAKREREEREQKEARLKANFFTMLRQRDQIKSYTRFRTVVKLCGALTPFLAVPERQREVYFEEYIQTMQREEKDRLRDMRKNSMDSFGRLLRSIPEITYKTSWKEAQELYGQRQRDEHLSFEGMDMLDFLSVFEEYNRALWEEPLGELNKRIQSRRRKDRKAREEFKVLLKELVAQRQINVRTLWKEIYPIIKDDPRYLAAVGLPDSTPLDMFWDVIDDLDEQLYQQKKLVYGTLKKANYDVDLESTFKDYLNALEADSHIKQEVNEDNLRFIFEHLQAKAAQRVKDEKRRQEKKLRKKLDIFRYILKHLQPPIQLEDSWETVKPRVEYLEEYKDIESEEAKQEVFEKYLKRLKEKKEDEEEEEEGMIREDEEGMIRDEDELMDKRRRSRRKDYDSENEEERNKKRRKHLSKSYSDAEEGEALDDYQNDPRRLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NHJ8</accession>
    <name>A0A1C7NHJ8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Isocitrate dehydrogenase [NAD] subunit 1, mitochondrial</fullName>
            <ecNumber evidence="5">1.1.1.41</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Isocitric dehydrogenase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">NAD(+)-specific ICDH</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="primary">IDH1_1</name>
        <name evidence="13" type="ORF">A0J61_03461</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>D-threo-isocitrate + NAD(+) = 2-oxoglutarate + CO2 + NADH</text>
            <dbReference type="Rhea" id="RHEA:23632"/>
            <dbReference type="ChEBI" id="CHEBI:15562"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.1.1.41"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="4">Octamer of two non-identical subunits IDH1 and IDH2.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the isocitrate and isopropylmalate dehydrogenases family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.41" evidence="5"/>
    <dbReference type="EMBL" id="LUGH01000149">
        <property type="protein sequence ID" value="OBZ88488.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NHJ8"/>
    <dbReference type="FunCoup" id="A0A1C7NHJ8">
        <property type="interactions" value="575"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NHJ8"/>
    <dbReference type="InParanoid" id="A0A1C7NHJ8"/>
    <dbReference type="OrthoDB" id="10261637at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004449">
        <property type="term" value="F:isocitrate dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006102">
        <property type="term" value="P:isocitrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.718.10:FF:000001">
        <property type="entry name" value="Isocitrate dehydrogenase [NAD] subunit, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.718.10">
        <property type="entry name" value="Isopropylmalate Dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019818">
        <property type="entry name" value="IsoCit/isopropylmalate_DH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004434">
        <property type="entry name" value="Isocitrate_DH_NAD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024084">
        <property type="entry name" value="IsoPropMal-DH-like_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00175">
        <property type="entry name" value="mito_nad_idh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11835">
        <property type="entry name" value="DECARBOXYLATING DEHYDROGENASES-ISOCITRATE, ISOPROPYLMALATE, TARTRATE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11835:SF42">
        <property type="entry name" value="ISOCITRATE DEHYDROGENASE [NAD] SUBUNIT BETA, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00180">
        <property type="entry name" value="Iso_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01329">
        <property type="entry name" value="Iso_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53659">
        <property type="entry name" value="Isocitrate/Isopropylmalate dehydrogenase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00470">
        <property type="entry name" value="IDH_IMDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="6" id="KW-0816">Tricarboxylic acid cycle</keyword>
    <feature type="domain" description="Isopropylmalate dehydrogenase-like" evidence="12">
        <location>
            <begin position="47"/>
            <end position="373"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007769"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011567"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00013012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00030631"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00030683"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00071938"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM01329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="OBZ88488.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="377" mass="41158" checksum="B4D010513817A16B" modified="2016-11-30" version="1">MLLKAIARPTVAKSAKKTAIRSFASIPTAAAVEQKSVFPKKYGGKYTVTLIPGDGIGQELAASVKDVFKAASVPVEFEQYDVSGITSTDDELFQESIASLRRNKVGLKGTLFTPTSRFGHKSFNVTMRKDLDMYASLSLCKNVPGVESRLSDVDIAIIRENTEGEYSGLEHQSVPGVVESLKIITRAKTERIARFAFDFAVKNNRKKVTIIHKANIMKLADGLFLRTCREVAKEYAHHDIQVNDMIVDNTAMQLVSRPQQFDVMVMPNLYGNIVSNVGAGLIGSPGLIPGCNIGREYAMFEPGCRHVALDIQNQNSANPTAMLLSSVMMLRHLNLDEHANRISSAVYETIGTNAAKTVDIGGTSTLKEFTNAVISKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NHU7</accession>
    <name>A0A1C7NHU7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 7">6,7-dimethyl-8-ribityllumazine synthase</fullName>
            <shortName evidence="7">DMRL synthase</shortName>
            <ecNumber evidence="3 7">2.5.1.78</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">A0J61_03254</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6 7">
            <text>(2S)-2-hydroxy-3-oxobutyl phosphate + 5-amino-6-(D-ribitylamino)uracil = 6,7-dimethyl-8-(1-D-ribityl)lumazine + phosphate + 2 H2O + H(+)</text>
            <dbReference type="Rhea" id="RHEA:26152"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15934"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58201"/>
            <dbReference type="ChEBI" id="CHEBI:58830"/>
            <dbReference type="EC" id="2.5.1.78"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 7">Cofactor biosynthesis; riboflavin biosynthesis; riboflavin from 2-hydroxy-3-oxobutyl phosphate and 5-amino-6-(D-ribitylamino)uracil: step 1/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the DMRL synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.78" evidence="3 7"/>
    <dbReference type="EMBL" id="LUGH01000137">
        <property type="protein sequence ID" value="OBZ88693.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NHU7"/>
    <dbReference type="FunCoup" id="A0A1C7NHU7">
        <property type="interactions" value="117"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NHU7"/>
    <dbReference type="InParanoid" id="A0A1C7NHU7"/>
    <dbReference type="OrthoDB" id="2965at2759"/>
    <dbReference type="UniPathway" id="UPA00275">
        <property type="reaction ID" value="UER00404"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005758">
        <property type="term" value="C:mitochondrial intermembrane space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009349">
        <property type="term" value="C:riboflavin synthase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000906">
        <property type="term" value="F:6,7-dimethyl-8-ribityllumazine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902444">
        <property type="term" value="F:riboflavin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009231">
        <property type="term" value="P:riboflavin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd09209">
        <property type="entry name" value="Lumazine_synthase-I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.960">
        <property type="entry name" value="Lumazine/riboflavin synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00178">
        <property type="entry name" value="Lumazine_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034964">
        <property type="entry name" value="LS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002180">
        <property type="entry name" value="LS/RS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036467">
        <property type="entry name" value="LS/RS_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00114">
        <property type="entry name" value="lumazine-synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21058:SF0">
        <property type="entry name" value="6,7-DIMETHYL-8-RIBITYLLUMAZINE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21058">
        <property type="entry name" value="6,7-DIMETHYL-8-RIBITYLLUMAZINE SYNTHASE DMRL SYNTHASE LUMAZINE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00885">
        <property type="entry name" value="DMRL_synthase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52121">
        <property type="entry name" value="Lumazine synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0686">Riboflavin biosynthesis</keyword>
    <keyword evidence="5 7" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007424"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022619"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00048785"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003795"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OBZ88693.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="195" mass="21161" checksum="7E416319AB8318E7" modified="2016-11-30" version="1">MSEKTFQKGVSAPKVKLDGSGLRVAIVHTRWNYALVDLLYKKVYDTLVERYNVKPENIHTDTVSGSYELPMAAKQLIELSQSQASETANDLLGSPAIGTAAAKSSGRKTGPFDAVICIGLVIKGGTAHFEYICDAVTHGIMRVQLDTGVPVVFGVLTCYNDEQAIARSSTEEGFHHAEEWAAAAIESGLRKYQKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NHV7</accession>
    <name>A0A1C7NHV7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">COX assembly mitochondrial protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">A0J61_03607</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Required for mitochondrial cytochrome c oxidase (COX) assembly and respiration.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Mitochondrion inner membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the CMC family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000158">
        <property type="protein sequence ID" value="OBZ88349.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NHV7"/>
    <dbReference type="STRING" id="101091.A0A1C7NHV7"/>
    <dbReference type="InParanoid" id="A0A1C7NHV7"/>
    <dbReference type="OrthoDB" id="6224010at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013892">
        <property type="entry name" value="Cyt_c_biogenesis_Cmc1-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08583">
        <property type="entry name" value="Cmc1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0143">Chaperone</keyword>
    <keyword evidence="2" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="3" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU364104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OBZ88349.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="102" mass="11861" checksum="711260EDBDFC0563" modified="2016-11-30" version="1">MGKSQEETMSNPFISKHSELHALTRQEEENCNKELKANALEACQLPIRDFVTCSKEHNVTVMWTCRNKLKTMNNCLKERTTQQELDKLLLAKLAKKRSDMHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NID4</accession>
    <name>A0A1C7NID4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_03185</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CDC123 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000133">
        <property type="protein sequence ID" value="OBZ88750.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NID4"/>
    <dbReference type="FunCoup" id="A0A1C7NID4">
        <property type="interactions" value="623"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NID4"/>
    <dbReference type="InParanoid" id="A0A1C7NID4"/>
    <dbReference type="OrthoDB" id="360540at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044183">
        <property type="term" value="F:protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:1905143">
        <property type="term" value="P:eukaryotic translation initiation factor 2 complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009772">
        <property type="entry name" value="CDC123"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15323:SF6">
        <property type="entry name" value="CELL DIVISION CYCLE PROTEIN 123 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15323">
        <property type="entry name" value="D123 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07065">
        <property type="entry name" value="D123"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ88750.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="352" mass="41405" checksum="F331534EEF93FF74" modified="2016-11-30" version="1">MTEDREIQKLTFVNISYRDIDNCSFSHWYPRFKANTFKSKILRLDQQFVDYLNAEGIYLPEDGQPKAATIEEYESDEEFIADDQEDKTPHFPEIEQAIRQAIYEFDGAVFPKLNWTSPRDAAWISATQTLKCTSPFDVFLLLKSSDFIEHDLNHAYENCGDVEDRPEKQTTYDLVLRKWYDLQPSMEFRCFVKDQEIIGITQRDTNFYPFLLDIQQDIEQQIFHFFEDVIHDQFDSVNYVFDVYIQRTNNKVFLVDFNPFSPTTDALLYDWHELMSFDLDKTQPEIRLVENQAQADVLSCHAPKFATNMIPRDVVDLSSGKSIAEFAQEFERAMKKTEEDGHTYDTTDDDSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NIF8</accession>
    <name>A0A1C7NIF8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">U3 small nucleolar ribonucleoprotein protein MPP10</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">MPP10</name>
        <name evidence="10" type="ORF">A0J61_03051</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Involved in nucleolar processing of pre-18S ribosomal RNA.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Nucleus</location>
            <location evidence="1 7">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6 7">Belongs to the MPP10 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000125">
        <property type="protein sequence ID" value="OBZ88897.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NIF8"/>
    <dbReference type="FunCoup" id="A0A1C7NIF8">
        <property type="interactions" value="574"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NIF8"/>
    <dbReference type="InParanoid" id="A0A1C7NIF8"/>
    <dbReference type="OrthoDB" id="445326at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034457">
        <property type="term" value="C:Mpp10 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032040">
        <property type="term" value="C:small-subunit processome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005732">
        <property type="term" value="C:sno(s)RNA-containing ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012173">
        <property type="entry name" value="Mpp10"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17039">
        <property type="entry name" value="U3 SMALL NUCLEOLAR RIBONUCLEOPROTEIN PROTEIN MPP10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17039:SF0">
        <property type="entry name" value="U3 SMALL NUCLEOLAR RIBONUCLEOPROTEIN PROTEIN MPP10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04006">
        <property type="entry name" value="Mpp10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF017300">
        <property type="entry name" value="snoRNP_Mpp10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4 7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 7" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="3 7" id="KW-0698">rRNA processing</keyword>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="95"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="509"/>
            <end position="539"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="113"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="192"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="263"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="283"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="294"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="unsure residue" description="I or L" evidence="10">
        <location>
            <position position="343"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00029455"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRNR" id="PIRNR017300"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OBZ88897.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="589" mass="68007" checksum="0767074B3ADA4CBA" modified="2016-11-30" version="1">MSSKKTDSIHQFITNIVEKPHVFFSADQTIADNALAMAKYFYDDVKKVEPVQFSPFTELLTEGFDNDQIWEEIAAQNEPFLDYAKTALKTFNRRSTLEDMSEESETDHSMDLDQAESDQAESDEAESDQAESDQAESDEEMEEFEDEGDMSETPAQVEKPSKGVHLRNTSKKTSEVDDEFFNLDEFNKWTEQQEELDMMSDREDQDDEFDFDRDLDDLEEESEEEEEMDEQDTTVAAELLYDDFYEKPMKNKPSPAKKVQFKEEEEEEKEDDASEGSVRDLFANDDSEEENDDEKSAFQKQQERLQAQIEEFEEENVQDRHWTLRGEASAGARPVNSLLEEDLEFEHGNKPVPVITQETTNTLEEVIKKRILDNMFDDVERKVDPTLKPFVPSKRVELSDEKSKKSLADMYEDDYLSKKTGEATTDARDEALEKEHADITQMFQELCHKLDALSNFHYTPKAPKPEMSIVSNTAAISMEEVTPVNVSDATLLAPEEIYDKKRTDVKAVTEMDQAERKRLRAQKKKMKRKERDMKERELKVMQKYNPKVGEKQSKQKAVKELLGQKNVTVIGKDGQKKTNTKTVTSASLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NIL7</accession>
    <name>A0A1C7NIL7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Multidrug resistance protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">ABCB1_1</name>
        <name evidence="12" type="ORF">A0J61_02987</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ABC transporter superfamily. ABCB family. Multidrug resistance exporter (TC 3.A.1.201) subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000121">
        <property type="protein sequence ID" value="OBZ88961.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NIL7"/>
    <dbReference type="FunCoup" id="A0A1C7NIL7">
        <property type="interactions" value="20"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NIL7"/>
    <dbReference type="InParanoid" id="A0A1C7NIL7"/>
    <dbReference type="OrthoDB" id="6500128at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015421">
        <property type="term" value="F:ABC-type oligopeptide transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090374">
        <property type="term" value="P:oligopeptide export from mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd18577">
        <property type="entry name" value="ABC_6TM_Pgp_ABCB1_D1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18578">
        <property type="entry name" value="ABC_6TM_Pgp_ABCB1_D2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03249">
        <property type="entry name" value="ABC_MTABC3_MDL1_MDL2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000205">
        <property type="entry name" value="ABC transporter B family member 4"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="entry name" value="ABC transporter type 1, transmembrane domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039421">
        <property type="entry name" value="Type_1_exporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43394">
        <property type="entry name" value="ATP-DEPENDENT PERMEASE MDL1, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43394:SF27">
        <property type="entry name" value="ATP-DEPENDENT TRANSLOCASE ABCB1-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="ABC transporter transmembrane region"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="40"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="88"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="164"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="188"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="268"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="302"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="700"/>
            <end position="728"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="748"/>
            <end position="774"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="825"/>
            <end position="844"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="850"/>
            <end position="867"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="933"/>
            <end position="954"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="966"/>
            <end position="986"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="11">
        <location>
            <begin position="44"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="10">
        <location>
            <begin position="362"/>
            <end position="604"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="11">
        <location>
            <begin position="704"/>
            <end position="993"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="10">
        <location>
            <begin position="1029"/>
            <end position="1271"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007577"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="OBZ88961.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="1277" mass="141743" checksum="9A819A4BC325C245" modified="2016-11-30" version="1">MTDYNKPIKKDSKALQDTADNKPDAIPIWRLFQFATPFEYCLIFIATLCSITSGIIQPISILFFGNVLRSFNEAALNHEDLMGKASPIITTYLLMGLVVLLASYFSSCLWILTGENQTRRIRQKYVHSVLRQDMGWFDKAEEGSLTTRLAADVQLIQEGISERFGQCIMCFAQFVAGCAVSFSKGWRLAAVMISITPALACTGGLMGIMVNKYTVAAQDAYAEAGSISEQVFAGIRTIYSFSLQERFARRYNDSLENAMIAGMKRGTVLGLGLGAYIFCLFSMYGLSFWYGATLVRAHVMDGPTVLVVFLSMMTGAFSLLQLPTNLAVVSSASAAAHKIFETIGRIPAIDTDSPKGAKPRKVRGEIIFRHVQFKYPARPDVTILKDFNLKIKAGTTVAFVGPSGSGKSTSVQLLQRFYDPVRGKVTLDGRNIKDLNVQWLRQQIGVVSQEPVLFNMSIRQNLMMGNTDSDVTSEDIVIACKKANCHSFIKQLPQGYDTLVGEHGGMLSGGQKQRIAIARAIIKDPAILLLDEATSALDTQSERLVQKALDKASADRTTIVIAHRLSTIRNADLIVVMQKGEIIEQGTHAELLSKGGMYSDLVKKQEIQTTLEDQAHSNDDDEALIKEETDELNRRSAIEMNRRSMIEIQSPRRSSILSFGRFSHISFIGESDAKEKQKSLEKKKQKAPVWRVFMQMRPQWSWMLLGSIGAFFAGSVFPMYSLFFSKVIMLLNANDDKSYGPLEGPNLYSFYFFLLGLAGFLGFSLQTVCFEIAGAKYTRTLRCMLFSAFMRQEIAYFDHNENSVGALTTKLAVDAKNVNEMITRVWADLIQIFCTTILGLTIAFLQSWKLTLIIMCMSPLIIIAAGWNSKVQEGYEDNTREANQQSSEVANEAIKQIRTVAALNQQIYFEGKYYEATDRPHQLARRKAFTSSIGFSLLQGVPLFTNAVAFYAGAKLIVQQELSLEGMIMTMMAIMIMADGIGRSSIFVPMFIKAKFAAIATFEVIDREPTIDPDLEGLELDHDEVNGNIAFDNIAFRYPARPDIPIFDGEFNLKGKSGQTIALVGPSGCGKSTTIGMLQRWYDPLRGHVRLDSYNVKSYSLNNLRSKMALVGQEPILFDLSIAENIRFGVDEDREVSQEEIEEACKAANIHKFITGLPDCYQTRVGEKGSQLSGGQKQRIAIARALIRKPKLLLLDEATSALDSESEKIVQEALDKILNEGGRTTITIAHRLSTITNADLICVIKGGKVIEQGNHWDLLKLNGVYADLVKQQSLNAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NIW7</accession>
    <name>A0A1C7NIW7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">IMS import disulfide relay-system CHCH-CHCH-like Cx9C domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_02856</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000114">
        <property type="protein sequence ID" value="OBZ89097.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NIW7"/>
    <dbReference type="InParanoid" id="A0A1C7NIW7"/>
    <dbReference type="OrthoDB" id="2581252at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005758">
        <property type="term" value="C:mitochondrial intermembrane space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045333">
        <property type="term" value="P:cellular respiration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.2900">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052848">
        <property type="entry name" value="CHCH_domain-containing_protein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031731">
        <property type="entry name" value="CX9C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47106">
        <property type="entry name" value="COILED-COIL-HELIX-COILED-COIL-HELIX DOMAIN-CONTAINING PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47106:SF1">
        <property type="entry name" value="COILED-COIL-HELIX-COILED-COIL-HELIX DOMAIN-CONTAINING PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16860">
        <property type="entry name" value="CX9C"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51808">
        <property type="entry name" value="CHCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="IMS import disulfide relay-system CHCH-CHCH-like Cx9C" evidence="1">
        <location>
            <begin position="6"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="domain" description="IMS import disulfide relay-system CHCH-CHCH-like Cx9C" evidence="1">
        <location>
            <begin position="52"/>
            <end position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF16860"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ89097.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="106" mass="12201" checksum="549A73A396292E42" modified="2016-11-30" version="1">MDDTLTQVREKCAIQLEAYQKCVESNPHSWDKSCMEQKKALTKCSEENVGILKYVKEHCTRQISAYDQCLSANTEKPEECVQALKDLYLCTEATSTAYREQQRKAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NJD8</accession>
    <name>A0A1C7NJD8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Nuclear distribution protein nudE 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">NDE1</name>
        <name evidence="10" type="ORF">A0J61_03011</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the nudE family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000123">
        <property type="protein sequence ID" value="OBZ88929.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NJD8"/>
    <dbReference type="STRING" id="101091.A0A1C7NJD8"/>
    <dbReference type="InParanoid" id="A0A1C7NJD8"/>
    <dbReference type="OrthoDB" id="5877028at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005871">
        <property type="term" value="C:kinesin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000776">
        <property type="term" value="C:kinetochore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008017">
        <property type="term" value="F:microtubule binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051642">
        <property type="term" value="P:centrosome localization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007059">
        <property type="term" value="P:chromosome segregation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000132">
        <property type="term" value="P:establishment of mitotic spindle orientation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007020">
        <property type="term" value="P:microtubule nucleation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047496">
        <property type="term" value="P:vesicle transport along microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.1080">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033494">
        <property type="entry name" value="NUDE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006964">
        <property type="entry name" value="NUDE_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10921:SF1">
        <property type="entry name" value="NUCLEAR DISTRIBUTION PROTEIN NUDE HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10921">
        <property type="entry name" value="NUCLEAR DISTRIBUTION PROTEIN NUDE HOMOLOG 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04880">
        <property type="entry name" value="NUDE_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57997">
        <property type="entry name" value="Tropomyosin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="4" id="KW-0493">Microtubule</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NUDE" evidence="9">
        <location>
            <begin position="144"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="216"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="312"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="32"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="220"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="257"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="315"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="10">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF04880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OBZ88929.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="359" mass="41742" checksum="C55A595B66FF7F73" modified="2016-11-30" version="1" fragment="single">ITNDKRHFLSHNKIYRQFNSAQEELDYWRSHAEDLESTLQDTRAALDEFQISSRELEEELEKELMTTEKAYSELKSRCEHFKRDAEDWKSKYTESKHEQNITMVQMQREIDILRATEDSFRKKVLELELDNDDLERTERAATSSLTDLEMKLNKAIERNVILENEIQAKDNLTEQAQRLRDELNEVHQELAVLRTQSVKQQEYIGELENKIEEVEKKNRQQAALQEQQQRSPTPDRASSGFYDPYSRSRATRIPRTSASGSISSSSNPVKMVQEMVGRVRSLEARLQSCRSLVTPLLNPPPSYSSSNYIHRDTHMSTGNSRPSSPDTMSIRSGSPMHFSNIKARRPSEYMKTSMDTNEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NJR7</accession>
    <name>A0A1C7NJR7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Nickel/cobalt efflux system</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">hoxN</name>
        <name evidence="9" type="ORF">A0J61_03203</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cell membrane</location>
            <topology evidence="8">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the NiCoT transporter (TC 2.A.52) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000134">
        <property type="protein sequence ID" value="OBZ88746.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NJR7"/>
    <dbReference type="STRING" id="101091.A0A1C7NJR7"/>
    <dbReference type="InParanoid" id="A0A1C7NJR7"/>
    <dbReference type="OrthoDB" id="5197598at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044750">
        <property type="term" value="F:high-affinity nickel cation transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098716">
        <property type="term" value="P:nickel cation import across plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004688">
        <property type="entry name" value="Ni/Co_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011541">
        <property type="entry name" value="Ni/Co_transpt_high_affinity"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00802">
        <property type="entry name" value="nico"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31611">
        <property type="entry name" value="HIGH-AFFINITY NICKEL TRANSPORT PROTEIN NIC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31611:SF0">
        <property type="entry name" value="HIGH-AFFINITY NICKEL TRANSPORT PROTEIN NIC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03824">
        <property type="entry name" value="NicO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0533">Nickel</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 8" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="38"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="105"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="146"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="205"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="246"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="288"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="334"/>
            <end position="357"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022596"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU362101"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OBZ88746.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="391" mass="43677" checksum="6723E59DCAD392FF" modified="2016-11-30" version="1">MSDSTGVLSRFALKFMSENSFGYKMFFGPDPHKVRFKVLLLLLGLSILQVVVWVIAVILFKPYPSMMGTGALAYTLGLRHAVDADHISAIDNVTRKLLNNNQHPVCVGLFFSLGHSTVVFITSIIVAATANAVANSIDHFSEIGGLIGTSVSIAFLVLIAILNLICMIGVIKTMRQVKKEGVYTEIDIEEFLSNRGILGRFFRPVFRFVNASWKMYPLGFLFGLGFDTASEVTLLGITAVQGANGMSMWLIILLPILFASGMALIDSLDSMLMLFTYTWAYVNPVRKLFYNLTITSISVVVAVIVALIELFSLIGEQLELDNGWWQFWYFLSDSFEWIGIIIVGAFIVTWFVSAVVYRLAGYRDLEREFDDYTPEKITTAVKNNNEIEEKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NKM6</accession>
    <name>A0A1C7NKM6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Alpha-1,2-galactosyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">gma12</name>
        <name evidence="6" type="ORF">A0J61_02330</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the glycosyltransferase 34 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000086">
        <property type="protein sequence ID" value="OBZ89625.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NKM6"/>
    <dbReference type="STRING" id="101091.A0A1C7NKM6"/>
    <dbReference type="InParanoid" id="A0A1C7NKM6"/>
    <dbReference type="OrthoDB" id="205108at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006487">
        <property type="term" value="P:protein N-linked glycosylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="entry name" value="Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008630">
        <property type="entry name" value="Glyco_trans_34"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31306:SF4">
        <property type="entry name" value="ALPHA-1,2-GALACTOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31306">
        <property type="entry name" value="ALPHA-1,6-MANNOSYLTRANSFERASE MNN11-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05637">
        <property type="entry name" value="Glyco_transf_34"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 6" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0808">Transferase</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="32"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="91"/>
            <end position="123"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OBZ89625.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="638" mass="72437" checksum="D456119CFDAD7750" modified="2016-11-30" version="1">MAGGSDLPFPNNSRAEGTSLFGGARFGRKKRTIIILLLVVVFFVLWFNSDLDRSSAVSVGNYVPDDATGISPDEQKASEHKNVLEEEEQLIEEEEEVQDMPVAHTEPVSTSKKPPTVKKPSESTLKPVTTISMTPQHFKYFVVIASKADSMSRRQLIRDTYFGQKDNIEPCMKRDKGVNYMFWVYGNEPTPKSAERRLYETEKMEWNDLEKVTATTYSQDAVLKWVNTNLAARGVTFDYLIIQDAHSVIQFNYIQQQVLNEVGKMWEVKKGATDLVWVSPEHENVLVAGSEAIKKVLENETQFKDIVAEGALMTNYYEFYRSIKVQLNFVTARKEVDRLVETMSQLPVFIEKDDSFITWTNTIESIPDMPIAVTDVYQDGDFASVAKTIKIGVTSLCKPLEKASIAVMTSSFIYADSCMEPSAALAADNKREYAKAHNYAFVARSTEFAQQEVRSVKRRTVWGKIDAVQKVLPRYDWLFWMDMDAVIMNPDITVQDILDDLRKKYPDGPRAFESKIDLVIAKPTKDKMINAGVFFLRNTPWAQKFLNDVQASKNWYNQGPSYEQGAMWDLIQLPGYKEHVLLLENDDHTFNTLPKRYVPGDFIVHFAPDKCPGPAVLKGLEAAQLIQEGEIITSFEEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NKN2</accession>
    <name>A0A1C7NKN2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">chitin synthase</fullName>
            <ecNumber evidence="2">2.4.1.16</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">CHS8_7</name>
        <name evidence="12" type="ORF">A0J61_04115</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.16" evidence="2"/>
    <dbReference type="EMBL" id="LUGH01000194">
        <property type="protein sequence ID" value="OBZ87834.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NKN2"/>
    <dbReference type="STRING" id="101091.A0A1C7NKN2"/>
    <dbReference type="InParanoid" id="A0A1C7NKN2"/>
    <dbReference type="OrthoDB" id="370884at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030428">
        <property type="term" value="C:cell septum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004100">
        <property type="term" value="F:chitin synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006031">
        <property type="term" value="P:chitin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031505">
        <property type="term" value="P:fungal-type cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="entry name" value="Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004835">
        <property type="entry name" value="Chitin_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014876">
        <property type="entry name" value="DEK_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22914">
        <property type="entry name" value="CHITIN SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22914:SF13">
        <property type="entry name" value="CHITIN SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03142">
        <property type="entry name" value="Chitin_synth_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08766">
        <property type="entry name" value="DEK_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109715">
        <property type="entry name" value="DEK C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51998">
        <property type="entry name" value="DEK_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="9" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="4" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="6 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="320"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="347"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="375"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="domain" description="DEK-C" evidence="11">
        <location>
            <begin position="550"/>
            <end position="605"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012543"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51998"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="OBZ87834.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="608" mass="70154" checksum="BECAF1148215552D" modified="2016-11-30" version="1">MIVGSGNDRSTPRIVLDILGVDPNLDPQPRSFLSLGEGRKQHNMGKVYSGLYDYSGHIVPYIVVVKCGTADERQKPGNRGKRDSQMVLMRFLNKVHYDAPMTPLELEIHHQLKNVIGVNPVFYEFVLMVDADTEVLPDSLNRMVSCFVNDAKIIGLCGETMLSNEKDTWITMIQVYEYYISHHLAKAFESLFGSVTCLPGCFCMYRIRSTTRHQPLLASNQVIKDYAENRVDTLHKKNLLHLGEDRYLTTLILKHFPTYKTKFTPDAACMTNAPDQWPVLLSQRRRWINSTVHNLGELMFLPQLCGFCCFSMRFVVMLDLLSTLVMPAVVMYLGYLVYQLFTNTNQVPLMSIITLAGVYGLQAIIFILRRKWEHIGWMIVYILAIPVFSFLIPLYAFWHFDDFSWGTTRIVVGEKGQKRAIRPEEGYFDPEEIPTKTWSEYEQEMTDNFDDTKHYAKQEKQPMDYPDYPSSTYSKKIQDNFSQSYTAINPPTDDRRLVYPATEVSSSHSYQYNLPNIASSLYSNHTKQHSQDYFYFSKPSSVRESSSFSIPSDSVIVQEIERILDHHNLMKLTKKQVRDMLSSLFGVDMTCKKEFINRCIDESLSSRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NKR2</accession>
    <name>A0A1C7NKR2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">GDP-L-fucose synthase</fullName>
            <ecNumber evidence="3">1.1.1.271</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">TSTA3</name>
        <name evidence="8" type="ORF">A0J61_04055</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Nucleotide-sugar biosynthesis; GDP-L-fucose biosynthesis via de novo pathway; GDP-L-fucose from GDP-alpha-D-mannose: step 2/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the NAD(P)-dependent epimerase/dehydratase family. Fucose synthase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.271" evidence="3"/>
    <dbReference type="EMBL" id="LUGH01000190">
        <property type="protein sequence ID" value="OBZ87894.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NKR2"/>
    <dbReference type="STRING" id="101091.A0A1C7NKR2"/>
    <dbReference type="InParanoid" id="A0A1C7NKR2"/>
    <dbReference type="OrthoDB" id="202470at2759"/>
    <dbReference type="UniPathway" id="UPA00128">
        <property type="reaction ID" value="UER00191"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050577">
        <property type="term" value="F:GDP-L-fucose synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016853">
        <property type="term" value="F:isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042351">
        <property type="term" value="P:'de novo' GDP-L-fucose biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd05239">
        <property type="entry name" value="GDP_FS_SDR_e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.25.10">
        <property type="entry name" value="UDP-galactose 4-epimerase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00956">
        <property type="entry name" value="GDP_fucose_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001509">
        <property type="entry name" value="Epimerase_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028614">
        <property type="entry name" value="GDP_fucose/colitose_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43238">
        <property type="entry name" value="GDP-L-FUCOSE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43238:SF1">
        <property type="entry name" value="GDP-L-FUCOSE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01370">
        <property type="entry name" value="Epimerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0413">Isomerase</keyword>
    <keyword evidence="4" id="KW-0521">NADP</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD-dependent epimerase/dehydratase" evidence="7">
        <location>
            <begin position="7"/>
            <end position="245"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005959"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OBZ87894.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="323" mass="37049" checksum="ED61EC3E3CE4CA83" modified="2016-11-30" version="1">MSTESVILVTGGTGLVGEAIKWVIENETDPRYGKKENEKWVFLSSKDGDLRKEEEVKAIFEKYKPTHVIHLAALVGGLFKNMKYKLDFLRDNMLINDNVLWQSKEHNVKKVVSCLSTCIFPDKTSYPIDETMVHNGPPHESNFGYAHGKRMIDVYNHAYKDQFGCHFTSVIPTNIFGPHDNYELEGSHVLPGLTHKCYLAKKNNTPFIVWGSGKPLRQFIYSRDLAKLFVWTLREYEEIDPIILSVGEEDEVSIKDVADGIVKAMDFQGEYAFDTTKADGQYKKTASNVKLMKYIPDFKFTPFDVAIKESVEWFVENYDSCRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NKS5</accession>
    <name>A0A1C7NKS5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="14">Putative cation-transporting ATPase 13A2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">ATP13A2</name>
        <name evidence="14" type="ORF">A0J61_02516</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000096">
        <property type="protein sequence ID" value="OBZ89419.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NKS5"/>
    <dbReference type="InParanoid" id="A0A1C7NKS5"/>
    <dbReference type="OrthoDB" id="48943at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019829">
        <property type="term" value="F:ATPase-coupled monoatomic cation transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140358">
        <property type="term" value="F:P-type transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.150.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, transmembrane domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023299">
        <property type="entry name" value="ATPase_P-typ_cyto_dom_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018303">
        <property type="entry name" value="ATPase_P-typ_P_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023298">
        <property type="entry name" value="ATPase_P-typ_TM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008250">
        <property type="entry name" value="ATPase_P-typ_transduc_dom_A_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059000">
        <property type="entry name" value="ATPase_P-type_domA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006544">
        <property type="entry name" value="P-type_TPase_V"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001757">
        <property type="entry name" value="P_typ_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044492">
        <property type="entry name" value="P_typ_ATPase_HD_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01494">
        <property type="entry name" value="ATPase_P-type"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01657">
        <property type="entry name" value="P-ATPase-V"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45630">
        <property type="entry name" value="CATION-TRANSPORTING ATPASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45630:SF11">
        <property type="entry name" value="CATION-TRANSPORTING P-TYPE ATPASE N-TERMINAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00122">
        <property type="entry name" value="E1-E2_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00119">
        <property type="entry name" value="CATATPASE"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG00002">
        <property type="entry name" value="C1.7:_P-type_atpase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00003">
        <property type="entry name" value="Haloacid_Dehalogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00027">
        <property type="entry name" value="p-type_atpase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81653">
        <property type="entry name" value="Calcium ATPase, transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81665">
        <property type="entry name" value="Calcium ATPase, transmembrane domain M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81660">
        <property type="entry name" value="Metal cation-transporting ATPase, ATP-binding domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00154">
        <property type="entry name" value="ATPASE_E1_E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0460">Magnesium</keyword>
    <keyword evidence="10 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="12" id="KW-0732">Signal</keyword>
    <keyword evidence="8" id="KW-1278">Translocase</keyword>
    <keyword evidence="3 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="12">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008889770" evidence="12">
        <location>
            <begin position="20"/>
            <end position="1426"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="161"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="268"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="315"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="460"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="493"/>
            <end position="517"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="673"/>
            <end position="694"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="700"/>
            <end position="722"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="1164"/>
            <end position="1183"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="1189"/>
            <end position="1206"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="1226"/>
            <end position="1251"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="1282"/>
            <end position="1300"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="1312"/>
            <end position="1330"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="1382"/>
            <end position="1405"/>
        </location>
    </feature>
    <feature type="domain" description="P-type ATPase A" evidence="13">
        <location>
            <begin position="533"/>
            <end position="655"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006000"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF00122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="OBZ89419.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="1426" mass="160945" checksum="C14954154C051CA4" modified="2016-11-30" version="1">MKINTVLCGLYAFIIGAAAIPLFEIPNDYDRYGNVCPLKQHNNVACPLLCVTNQNLCPSALAASCPEGLQFCGDGTCQASCKDIANACQCGDDTVQYYPCAAGQLVNISHFDPNNQVVQTQNTCAANVNLSNIGTWGEFSNPSVWLSCPVVEPYFTFKEPMWIAVWCLMSAEAVILLLWAIYKYVREMKFHTIMASNALDKDSTRMKSSHDPDAVIKVNSQVNEAECQKDMMVSEKKQFXSAKDDSTIATDSIKESEKLRFRGFLVDYFGLFAFGSVVVTTLLFFVFLGCIVGDYYGTMGGQFAIFLSSDVSSKVFSAVWHIAAAWFCLVMFKKKTIRNYFRIESFPHNCPYVQIERKQDELIFLADGSKWISKLRALEQRVNDRLGLNMVITTCSVKVTENKLRYFEYQCMRYIYNNDKGRFEPYEFDLGSTNRQLQAWSKGVSTEEANRRAALIGENLIRVTVPSIPLAIIQEFSSFLYLYQMMCMWVWYYFQYFIMGLVQTGIILVAAFIRVILRLRAEHRIKEMAEHVTDVTVLRDGEWKSTSSANLIPGDVFEVEENTIIPCDSVILSGTVVVNESSLTGEAMPIRKFAIANDDNAYEMNGSGKVNTLFAGTIVSQTTPTITSDTTDEKGRVYALALRTGISSEKGMLIHKILFPSPVSFIFNEHLKVAISILLVWGLVAFALSLYLMGRGNINSWFYGVFVISEIFSPLLPAAFTINQSVCATRLRKNKILCIDLPRINLSGKVRIFCFDKTGTLTREGLEFYGGVAAPPAPIAPFGYREEDPLKMEPLLAMGIATCHAVTEVKGQFIGNPVDIESFNAMKWTLLPPDHPDYLDTLAMPSSTPVDEKDKKRVHVIRRFEFVHARASQSVAVLDPETQHVHVFLKGSFERIKYLSSPDSVPADYDDQAAKYAQEGCYVLAMASRDIGVLGQDVTMEQIKSMTRDELEQDCDFVGFILFRNMLKHDTTQAIEELKGGDTRVVMITGDTALTGIFIARQCGMIEPHQRVLLGDVVSGTVVWRDIDSNEEVDVDHVIELDPREEHEKRVELAVTGRAFEALIKEDRMRKYLLMTRVFARMTPNDKVMCVQLHMEKXVTAMCGDGGNDCGALRAAHVGLALSEAEASIVSPFSTSNRSIMQCVELLKQGRSALATSFANYKFLILYGECMACWELIMFYFTVIAYQSVWITIDGFITTTMTLAITQAQPAKKLSPSRPTAKPLGLYTLASLLGVIFINFWFIVCSVVWLFQQDWFICNEFDSSSINSAQWWLLGDNYEAEVISLVIIFQFFNNAAVVNFGTQFRQSWWRNYALVFVWICFFVSTSYMTLADPNPYSCIFRINCGTASVLEELGYPKPYWNIPEYNSPIGHNVLPEYFRWQLWGYILANCAATIIWERICVLWIARDWAIKRKKTHPKENRIVFKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NLG4</accession>
    <name>A0A1C7NLG4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Nitrogen assimilation transcription factor nirA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">nirA_0</name>
        <name evidence="4" type="ORF">A0J61_01943</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000068">
        <property type="protein sequence ID" value="OBZ90001.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NLG4"/>
    <dbReference type="STRING" id="101091.A0A1C7NLG4"/>
    <dbReference type="InParanoid" id="A0A1C7NLG4"/>
    <dbReference type="OrthoDB" id="4161332at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050987">
        <property type="entry name" value="AtrR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46910:SF1">
        <property type="entry name" value="MISCELLANEOUS ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46910">
        <property type="entry name" value="TRANSCRIPTION FACTOR PDR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Xylanolytic transcriptional activator regulatory" evidence="3">
        <location>
            <begin position="294"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="626"/>
            <end position="753"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="786"/>
            <end position="808"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="646"/>
            <end position="659"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="715"/>
            <end position="728"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="793"/>
            <end position="808"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OBZ90001.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="931" mass="105107" checksum="4294284B701EA7BD" modified="2016-11-30" version="1">MYEEPPPLPFPSLTSLKSTAIDILKSQRSPNTPDVEFKFCYPEQSGQTEKRRLKPNNKACDVCKKKKIRCDINALPHEPCTRANCQCEHHHQHFVSTEEASHSSEMMVTNTNSESIPSTTVFRKPGLLHSGHYTGETSFCGYLRAQNQPPVITKEDQYPTFSTLPLPPIAPNISSADQRYLIDVYYDNLNPFYPIINKTDMLEQLDLVQKKSSSYLSPLFFFALFARAAHVESNRQYTEDRQFTFHDLGIACLDYASALVHYYKDKPRISTVLALVIMTNHLEQEKKHRDLTKTWLWAGDAFRMALDLGIHRSFISKESDSFGQLCIRTFWLAYIADCTVSMTYGRPSATEEKVLDVTYPSKLPNDDDYATQWIDGLSSLISLSKVTARVIKFNYCPPPPFIIQGPVKRHNAFLVSVDSWLMDIISPVKEGEEPEEPESPLSQLPNTFKDESLISARITLQKKMFLYANLILLHRPYVNDVLTTRNTSNRPSYDICSYAAIIITDLASKLDPAELVYHSKSPLMAYALVMALRIHIMNATNANPEKYNAQKNFNLCLATLNRLPQAKDTSSMLYEALVDLVEQYNDRFLLAQEREDDIKLQQQLHQQMNLRQPVITAAQVVFSPGAIDKRKDRPNSDASNGVPLMSFNTSLDSSGSQPNRLVIKHHQHSADPNNRKKKKVKATHDSPAMTVESSKHKPKQPQQKPNKTFSEFQHMSSPQLSMQPPSSSNISRSNAKTPRQRQRQQQQQQAIQPVPFDAQLSSSTTSTSSFGQFSFSGQANPFIPTQYTNINKSNSHSSSSSSVSSTNTFSHSDNYYAAPLPNQGNNDLVNQPTNDIMQPYDFTPNMFPFGEDISFDEVLSKMNTYQNTFLSNLNPSSLINNGFVNDNFSTELMAMYHFTPQDSAIGISVSKGPNEMMIPSNDTNNSALDFP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-06-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NLJ0</accession>
    <name>A0A1C7NLJ0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_02070</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000074">
        <property type="protein sequence ID" value="OBZ89868.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NLJ0"/>
    <dbReference type="InParanoid" id="A0A1C7NLJ0"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="24"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ89868.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="94" mass="10213" checksum="5556310CBFDC766A" modified="2016-11-30" version="1">MQRCLSGPEVSEIKLEVDLFLSSSTSPSPDVDAEEVKDNSECGLSPDDPSETRLRSPFAKKEISFLSTSASDTIGGGVFFKHLAKAIIHMNARR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NMF8</accession>
    <name>A0A1C7NMF8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_01597</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000053">
        <property type="protein sequence ID" value="OBZ90343.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NMF8"/>
    <dbReference type="InParanoid" id="A0A1C7NMF8"/>
    <dbReference type="OrthoDB" id="2236116at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ90343.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="62" mass="7076" checksum="4749FB87A3EC9AFB" modified="2016-11-30" version="1">MISKLTLFINTLKRTRSTKKKNQYWVDHAQEAFGGTAENMRVLLSTLTVSESHTEMSVSLFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NMS9</accession>
    <name>A0A1C7NMS9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Ran-binding protein 10</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">RANBP10_0</name>
        <name evidence="3" type="ORF">A0J61_01675</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000056">
        <property type="protein sequence ID" value="OBZ90270.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NMS9"/>
    <dbReference type="STRING" id="101091.A0A1C7NMS9"/>
    <dbReference type="InParanoid" id="A0A1C7NMS9"/>
    <dbReference type="OrthoDB" id="25503at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.920">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001870">
        <property type="entry name" value="B30.2/SPRY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043136">
        <property type="entry name" value="B30.2/SPRY_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006594">
        <property type="entry name" value="LisH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003877">
        <property type="entry name" value="SPRY_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050618">
        <property type="entry name" value="Ubq-SigPath_Reg"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12864">
        <property type="entry name" value="RAN BINDING PROTEIN 9-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00622">
        <property type="entry name" value="SPRY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00667">
        <property type="entry name" value="LisH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00449">
        <property type="entry name" value="SPRY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50188">
        <property type="entry name" value="B302_SPRY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50896">
        <property type="entry name" value="LISH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="B30.2/SPRY" evidence="2">
        <location>
            <begin position="76"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="23"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="429"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="32"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="433"/>
            <end position="446"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50188"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ90270.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="628" mass="69878" checksum="049CF5818DE2D3C6" modified="2016-11-30" version="1">MTTAYSSAFPPLQSFSPWSIPNNKNVTKRHSSPVTSTTHHCPANSQFVTTPLSPPKYPSYLKHTRYASLVMEQYHHLLNKQRTYDHIETTDLRLPQYWNKNDKSRSIEVGMNGLDLSYVLGSGKAAHATQQNMAEAATVRTHFPVRAQCGVYYFEIKVNALGLDGLFAIGLCSLQHKLDVLPGHDAFSFGYHGQSGQIFKQKQAQDYGPNYSSGDVIGCGVNFATGNVFFTKNGIFLGSAFEFDTDASYYPCVGLSTPGERMTANFGQEPFLFDIVHYIKDQHVSFNQSIQSYSKDKASIDQMVASYLIHLGYTETAKSLLKNSHQLNPTKQETSVCLSDDDINMNHLRQTIMSGGCMDVALNQIQTEYPGLLEAHPDLHFELKTRKFLDFFMATPDTHPLLQPSSSCSSTPSLASSLCLSDPIAEDTDDDTLSSYSGRSRTLSISSEDEKPGFPFGHAMPLISPPMHVAASGRRLSWAAVAASPNTNLFESHCDSPLTAKRRPSLFTRQKSLDEEETGLPESSVRQAMLYGQSLQEEYQHQPKYQHRLMELFCLLTMSDPKTSTEGPLLTLAARDATVSRLIKAIRAYKHQSKTSTLEMAYKQTMTVTKELSLSGHGKASLIQFEYH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NNR3</accession>
    <name>A0A1C7NNR3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Inner spore coat protein H</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">cotH_1</name>
        <name evidence="2" type="ORF">A0J61_01334</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000041">
        <property type="protein sequence ID" value="OBZ90620.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NNR3"/>
    <dbReference type="STRING" id="101091.A0A1C7NNR3"/>
    <dbReference type="InParanoid" id="A0A1C7NNR3"/>
    <dbReference type="OrthoDB" id="2387105at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014867">
        <property type="entry name" value="Spore_coat_CotH_CotH2/3/7"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40050">
        <property type="entry name" value="INNER SPORE COAT PROTEIN H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40050:SF1">
        <property type="entry name" value="INNER SPORE COAT PROTEIN H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08757">
        <property type="entry name" value="CotH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0167">Capsid protein</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0946">Virion</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008889808" evidence="1">
        <location>
            <begin position="19"/>
            <end position="524"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ90620.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="524" mass="59163" checksum="1038F4A6241536EF" modified="2016-11-30" version="1">MKFSLFAASACLLSAVQAATVEFKIVAPGAKSVQVNVNGQATALNAPYPNVPFYNGTVEVGASNSYNYIVDGKQEGFARSLPANILATNNDFYNRPITIASVPALPRPLDNGKQWTKADKNPDLFDTNFIPTVFVNGDESQINNLVETVPKDKVTVELTFIGRDYVQQFRNVSLGISGAGKKHNPAKQSWRWYLSEGDFINNRNIFKIRHMEEDPTQMREKLYADVLRAMGTYANQANMVRFYMNGEGYGTFNMLEDVDRYSYIRATFYGGNPPAQMGPVYDGGSGASFKYSEDTDGYSSFEPTKGSPEGYEAIAPLAEAFSKLNLQDNNAIQEFEKMFDVDQFLRFMVMEYLTGSWDAYWMMQTNDGAYKDYADNNKWYYLGQDYDATFGVNLAEDVMNLSYKDYIEKNPEAVLINGFLQNNDLRSRFESYLVDTVKTLFNNNTLGNHIMTYREFIAPDLEWDRSIKQRSPGMVFNWSYEQTYENLFHGVDSPTDGIGGAAYGLTEWIAKKAAVVAKEFNFTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NNW0</accession>
    <name>A0A1C7NNW0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_01293</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000039">
        <property type="protein sequence ID" value="OBZ90660.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NNW0"/>
    <dbReference type="STRING" id="101091.A0A1C7NNW0"/>
    <dbReference type="InParanoid" id="A0A1C7NNW0"/>
    <dbReference type="OrthoDB" id="2351940at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="41"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ90660.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="268" mass="29748" checksum="CCB215F71A6D1711" modified="2016-11-30" version="1">MPNVNRFTSADDIIPASAFTVSPILTSNLLDEIDSAVARDTSNFSHSTTPPAPPPSTRWSRRLTSSNLHCLSEKAFDTSSLLKENEEAHDILDFEIMCNDGGRFGEMYGIENVLLNDGSVYCSGRKGTVNILVRYCGFIQSGLIADTNCSITKMVLKAPQHGFSAPCKEGLVFISHREINIQDTSKFDHFSKAEYEQYRLSNNQDTDPVAWFSLSKERTCIVDLEARSAKYVLIKLLRAETESDNIDIQYIGFIGFSGARSFSSAKLC</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NPL5</accession>
    <name>A0A1C7NPL5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">eIF-2-alpha kinase activator GCN1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">gcn1</name>
        <name evidence="6" type="ORF">A0J61_00876</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the GCN1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000023">
        <property type="protein sequence ID" value="OBZ91073.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="FunCoup" id="A0A1C7NPL5">
        <property type="interactions" value="991"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NPL5"/>
    <dbReference type="InParanoid" id="A0A1C7NPL5"/>
    <dbReference type="OrthoDB" id="5148094at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030295">
        <property type="term" value="F:protein kinase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034198">
        <property type="term" value="P:cellular response to amino acid starvation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1904688">
        <property type="term" value="P:regulation of cytoplasmic translational initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.10.10:FF:000090">
        <property type="entry name" value="eIF-2-alpha kinase activator GCN1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.10.10:FF:000096">
        <property type="entry name" value="eIF-2-alpha kinase activator gcn1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022716">
        <property type="entry name" value="Gcn1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056810">
        <property type="entry name" value="GNC1-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000357">
        <property type="entry name" value="HEAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057546">
        <property type="entry name" value="HEAT_GCN1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056809">
        <property type="entry name" value="HEAT_GCN1_fung"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021133">
        <property type="entry name" value="HEAT_type_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034085">
        <property type="entry name" value="TOG"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23346:SF7">
        <property type="entry name" value="STALLED RIBOSOME SENSOR GCN1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23346">
        <property type="entry name" value="TRANSLATIONAL ACTIVATOR GCN1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12074">
        <property type="entry name" value="Gcn1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24993">
        <property type="entry name" value="GNC1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02985">
        <property type="entry name" value="HEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24984">
        <property type="entry name" value="HEAT_EF3_GNC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24987">
        <property type="entry name" value="HEAT_EF3_N"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23271">
        <property type="entry name" value="HEAT_GCN1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24916">
        <property type="entry name" value="HEAT_GCN1_fung"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01349">
        <property type="entry name" value="TOG"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50077">
        <property type="entry name" value="HEAT_REPEAT"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="TOG" evidence="5">
        <location>
            <begin position="1376"/>
            <end position="1606"/>
        </location>
    </feature>
    <feature type="repeat" description="HEAT" evidence="4">
        <location>
            <begin position="1547"/>
            <end position="1585"/>
        </location>
    </feature>
    <feature type="repeat" description="HEAT" evidence="4">
        <location>
            <begin position="1666"/>
            <end position="1704"/>
        </location>
    </feature>
    <feature type="domain" description="TOG" evidence="5">
        <location>
            <begin position="1694"/>
            <end position="1962"/>
        </location>
    </feature>
    <feature type="repeat" description="HEAT" evidence="4">
        <location>
            <begin position="2024"/>
            <end position="2060"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007366"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00072275"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM01349"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OBZ91073.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="2413" mass="266228" checksum="2B6D21FE1ADF0FBA" modified="2016-11-30" version="1">MADLQENTGELGWPEFIRTRVMTTITYSGVSDRLDFLNHVLLIRIRRKDLPVEALPSLLQLIFLTIPRYQDRASRVAIIEVLKELNNWNAEVFQKVLVPVIVREAERYGKRKPTGECVFPAADRFVLLTWINVLFSCVLKKVTIEGAKTNIMFSSVLNAQAVLIDSLMNDAKKTITKSAVADVRRTIRNNAEAIPVILHVALNNAQTCTPSFKNAVLIGTVIDVSIRLKTRQDGKAMIEQAEPQLIEYYLKNIVSSRTAVHLGALDAFNDFISTFITKEKFEKDFLPVLDKVMLRSPEVVLLALARATPAFSFDPSDIFANKWLDSLLNQLRSTSPTTVHGAKSFWEALACKCHGTDSLVKVADGISKLLTSGKVSSWEHRVVIYNALSSLAQVTEPTVSQKALESYFAMTVKEAHEQAMAAAVDGIGRHLTVLIYNDEFCAANQDFVNKAVKASADGLQAAKPLARKSWAQAVGSTVWNHQGAASATLSANIVKYLQALFKTFSTVVDKPLVWKDGPLEVYVMIAMISGRIQHWPAIPPAVVDLLKSQKYPSQLLVSSPKPSYLLWDRIYTKALSADEGTWFIRALAHVFMNESQDSLQSTGAGHLAAVALIWIATSHPEHTVRRAAFDEIAVIAAKDASKLNCFMKPAVKQWLLDIEHNIKDSTAVVATNTDDYREDIAVSRLASILYSMTSFSSDLPESSKGVELIDLMVLSHHKLIASPTNKYNWITLAQRAHVDPGKLVKEKEHKVLEILKQALQARQESELFYQAAISAISTLVFISPESIVEFVDFAEQNLNPELTKDIGELESNIWKAPADTPFVDVLNKNKKTESRNNRKGKNDDEWEEELRAELAKKKGVAQKLTKEEQAAVNAQLRKETEIRAHVQSVHDKLTLGLDVVRSIVNGNSEAAEEYLVDLVRILISAGKHQAGRLVGELLVDTYCQLGHCVAEDIQPIRDAIALATLRANRIQPIPMRWLDEPLGALVSRVLFRLRFITESRALPPASFGFVFPVLYQVIAQGGVGCEKNDEAILEQITMAIDVINFHCIHGESLILPRQEMIDILLRSIKDYPACSKTAKTSLVTLCESMGDTDEQNEIDTLLQGLLSSEVLVRTAALQALELLDLTDIDYSPQLWVARHDDNESNAELAKAQWEDNAMEVEENFRDQLLEYVVSDSNYVRQAASQALAEAVEEYPESAYDTLQAIYAMYKKLAAPLDPEYDEYGMVIPETLDRVDPWEARVGLALTLKALAPLMQLENAANFCKFLINEQALGDRNEQVRRRMLEAGMAAINAYGNVDIEGFLETFETYLNSPTDNSDVQDHIRQAAVILYGGAAGYLNPGDEKVSTAVEKLIETLDTPSETVQSAVADCLPPLIKMCKDEVPRLIKSLLNKLFKGEKYAHRRGAAYGLAGVVKGRGITALKECNVMNSLKDAVDNKRMYEYRQGALFAFETLSATLGRLFEPYIIQIIPLLLVCSSDANIDVREASSDAARVIMSKISGHCVKLILPSILEGLEERQWRTKKASVELLGSMAYCAPKQLSVSLPNIIPRISEVLADTHSQVQAAANRSLQLFGEVISNPEIQELVPVLLKALSDPNTKTAPALTALLQTSFVHYIDPPSLALVMPILERGLRERATEIKTKSAQIVGNMASLTDQKDLVPYLNIIMPGLHGVLVDPVPAARGTAAKALGALVEKLGEENFPGLVLDLLDTLKTDSGGVDRQGAAQGLSEVLAGLGLERLDGLLPEIISNADSPRAYVREGFISLLIYLPATFGTRFQPYLGRIIPPILTGLADESEYVREASLRAGRMIVTNYATKAVDLLLPELEKGIFDNKWRIRQSSVQLVGELLFRITGITHKNNDMALGNVDELADDEVDAGYEDYGSDNKKKQLVEVLGKERRDRILAALYIVRQDSSGVVRQASLQVWKVLVSNTPRTLKDIMISMVSMIIKILASDNFEQRAVAGRTLGDLVQKLGEGILPEILPVLEQDMQSDDESIRLGVTLAYSEIMTSADKVQVMDFADQIIPVVKGALCDPSEEVREAAAQAFDTLHQNIGAKAIDGILPSLLNKLQSSDESSSYALSALKEIMSVRSNVVFPVLIPTLITVPISAFNARALASLVTVAGPALNKRLIAILDALIETLMAEEDEETIQALKATTEAFLLSVDDEDGLHTLIVTLMEYVRDDNPLKRAVSCDITAQFFTESELDASYYIPDWIHLLMLLLDDPSEQVIQSAWNALSAITKSLPKEEYEELVAPTRHAITTAGQAGVDIPGFCLPKGIGCVLPIFLQGLMYGSNDVREQSALAVGDLIERTDATALKPFVTQITGPLIRILGDRYPAEVKAAILQTLSLMLNKVPMHLKLFLPQLQRTFVKSYSDSTSDIVRERAVTALKALSALQPRVDPTVAEILKNES</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NPV3</accession>
    <name>A0A1C7NPV3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">H/ACA ribonucleoprotein complex subunit 2</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Nucleolar protein family A member 2</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="primary">nhp2</name>
        <name evidence="11" type="ORF">A0J61_00887</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Common component of the spliceosome and rRNA processing machinery.</text>
    </comment>
    <comment type="function">
        <text evidence="8">Required for ribosome biogenesis. Part of a complex which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Pseudouridine ('psi') residues may serve to stabilize the conformation of rRNAs.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 8">Nucleus</location>
            <location evidence="1 8">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the eukaryotic ribosomal protein eL8 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000023">
        <property type="protein sequence ID" value="OBZ91058.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NPV3"/>
    <dbReference type="FunCoup" id="A0A1C7NPV3">
        <property type="interactions" value="488"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NPV3"/>
    <dbReference type="InParanoid" id="A0A1C7NPV3"/>
    <dbReference type="OrthoDB" id="5364946at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031429">
        <property type="term" value="C:box H/ACA snoRNP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034513">
        <property type="term" value="F:box H/ACA snoRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000493">
        <property type="term" value="P:box H/ACA snoRNP assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000454">
        <property type="term" value="P:snoRNA guided rRNA pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031120">
        <property type="term" value="P:snRNA pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1330.30:FF:000015">
        <property type="entry name" value="H/ACA ribonucleoprotein complex subunit NHP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050257">
        <property type="entry name" value="eL8/uL1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002415">
        <property type="entry name" value="H/ACA_rnp_Nhp2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029064">
        <property type="entry name" value="Ribosomal_eL30-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004037">
        <property type="entry name" value="Ribosomal_eL8-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004038">
        <property type="entry name" value="Ribosomal_eL8/eL30/eS12/Gad45"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018492">
        <property type="entry name" value="Ribosomal_eL8/Nhp2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23105">
        <property type="entry name" value="RIBOSOMAL PROTEIN L7AE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01248">
        <property type="entry name" value="Ribosomal_L7Ae"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00881">
        <property type="entry name" value="L7ARS6FAMILY"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00883">
        <property type="entry name" value="NUCLEARHMG"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55315">
        <property type="entry name" value="L30e-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01082">
        <property type="entry name" value="RIBOSOMAL_L7AE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 8 11" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="5 8" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4" id="KW-0698">rRNA processing</keyword>
    <feature type="domain" description="Ribosomal protein eL8/eL30/eS12/Gadd45" evidence="10">
        <location>
            <begin position="44"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007337"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU366039"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF01248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="OBZ91058.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="162" mass="18088" checksum="603A9F25D01D26E5" modified="2016-11-30" version="1">MAKEQKKEKKVKAPKNEGSDNEEEVLRFQSPIAHPLAEKKLVKKLYKTIKKASKVKHVRRGVKEVGKALRKGEKGLVVIAGDISPLDVISHMPVLCEDSNVPYIFVPSKEQLGEASSTKRPTSVTMIVFGGKNKDTKAAADYKELYDECYAQAKDLDEKLVY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NQ88</accession>
    <name>A0A1C7NQ88_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">DSC E3 ubiquitin ligase complex subunit 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">dsc3_0</name>
        <name evidence="4" type="ORF">A0J61_00891</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000023">
        <property type="protein sequence ID" value="OBZ91079.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NQ88"/>
    <dbReference type="FunCoup" id="A0A1C7NQ88">
        <property type="interactions" value="9"/>
    </dbReference>
    <dbReference type="InParanoid" id="A0A1C7NQ88"/>
    <dbReference type="OrthoDB" id="2556122at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044695">
        <property type="term" value="C:Dsc E3 ubiquitin ligase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045226">
        <property type="entry name" value="Dsc3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025390">
        <property type="entry name" value="Dsc3_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019413">
        <property type="entry name" value="Dsc3_ub-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000626">
        <property type="entry name" value="Ubiquitin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28049:SF1">
        <property type="entry name" value="DSC E3 UBIQUITIN LIGASE COMPLEX SUBUNIT 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28049">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN YOR223W"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13373">
        <property type="entry name" value="Dsc3_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10302">
        <property type="entry name" value="Dsc3_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50053">
        <property type="entry name" value="UBIQUITIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0436">Ligase</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="177"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="210"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="domain" description="Ubiquitin-like" evidence="3">
        <location>
            <begin position="7"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="89"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="92"/>
            <end position="102"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OBZ91079.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="228" mass="26497" checksum="0A13D62DA24A7911" modified="2016-11-30" version="1">MMTGNDLNLHIRWNNQPDLVLSIHYTSDTIQSIKQKIKMAAPRQTDQKMLRLIYRGQLLDQDQAQLSDYGIIYQPRLFFHCALSDNTLSKSQQQQHQQGQQQNRERHHTKRLTGFDQLIESGYNEEEIRSIRVRFHQSHPDYVDGEPVSQELLELEQAWIEQNGHFIPPEESVQGSFKEMVCGLMLGCLLGILCLFWLKESVFTRRHQMGILAGMLINVSCGVMHVYS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NQ97</accession>
    <name>A0A1C7NQ97_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">AP-1-like transcription factor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">pap1</name>
        <name evidence="6" type="ORF">A0J61_00840</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000022">
        <property type="protein sequence ID" value="OBZ91089.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NQ97"/>
    <dbReference type="STRING" id="101091.A0A1C7NQ97"/>
    <dbReference type="InParanoid" id="A0A1C7NQ97"/>
    <dbReference type="OrthoDB" id="2593073at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090575">
        <property type="term" value="C:RNA polymerase II transcription regulator complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001228">
        <property type="term" value="F:DNA-binding transcription activator activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000976">
        <property type="term" value="F:transcription cis-regulatory region binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd14688">
        <property type="entry name" value="bZIP_YAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.170">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.100">
        <property type="entry name" value="YAP1 redox domain. Chain B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050936">
        <property type="entry name" value="AP-1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004827">
        <property type="entry name" value="bZIP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046347">
        <property type="entry name" value="bZIP_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023167">
        <property type="entry name" value="Yap1_redox_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40621:SF6">
        <property type="entry name" value="AP-1-LIKE TRANSCRIPTION FACTOR YAP1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40621">
        <property type="entry name" value="TRANSCRIPTION FACTOR KAPC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00170">
        <property type="entry name" value="bZIP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00338">
        <property type="entry name" value="BRLZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57959">
        <property type="entry name" value="Leucine zipper domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111430">
        <property type="entry name" value="YAP1 redox domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00036">
        <property type="entry name" value="BZIP_BASIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BZIP" evidence="5">
        <location>
            <begin position="100"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="36"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="178"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="41"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="62"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="191"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="210"/>
            <end position="223"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS00036"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OBZ91089.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="426" mass="47430" checksum="ECA4D59AA8F7170E" modified="2016-11-30" version="1">MSLTSDTLQFNLNDTALDLLNAAIASHHQIGTENNSLLIDKTNKPEDKEITPKQKTSPGTHTKRELDKDEQTTITAPKRAGRKPLEKSAAAEASLDPKQKRKAQNRAAQRAFRDRKEKHVAELQARIAELEALNSKKDEDLVKENEKLKEQLKKLQEENYALKGAQFTFEFPVADHQHPVYHHPSDAQYQTTTSSSSISSSNSYSGEDGTCSSTEHSPLSNPNTHDDDSPTTADAQLFASTPLQFGPIVDNTPDFLAMSVTHGFGNDLTGSHNFSVTNSDLVFPTGDLFHGKDDPFTNYQAPSTNNLNDDFLFANENLSNLFGPTDDIFSGNQFALNTQFGLPETPAIRRNKISAEKKKCLIDKLKKGQQEGKYVYQVHQEIRQQCPDFDLDSLCDELKMKAQCSLSTHLVTDREVEAFVKCLDKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NQK9</accession>
    <name>A0A1C7NQK9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Polyadenylate-binding protein</fullName>
            <shortName evidence="13">PABP</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="primary">PAB1_1</name>
        <name evidence="17" type="ORF">A0J61_00528</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">Binds the poly(A) tail of mRNA.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 13">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 13">Belongs to the polyadenylate-binding protein type-1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000012">
        <property type="protein sequence ID" value="OBZ91397.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NQK9"/>
    <dbReference type="FunCoup" id="A0A1C7NQK9">
        <property type="interactions" value="458"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NQK9"/>
    <dbReference type="InParanoid" id="A0A1C7NQK9"/>
    <dbReference type="OrthoDB" id="19742at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051028">
        <property type="term" value="P:mRNA transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006417">
        <property type="term" value="P:regulation of translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd12378">
        <property type="entry name" value="RRM1_I_PABPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd12379">
        <property type="entry name" value="RRM2_I_PABPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd12380">
        <property type="entry name" value="RRM3_I_PABPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd12381">
        <property type="entry name" value="RRM4_I_PABPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1900.10:FF:000004">
        <property type="entry name" value="Polyadenylate-binding protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.330:FF:000003">
        <property type="entry name" value="Polyadenylate-binding protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.330:FF:000441">
        <property type="entry name" value="Polyadenylate-binding protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.330:FF:000520">
        <property type="entry name" value="Polyadenylate-binding protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.330:FF:000648">
        <property type="entry name" value="Polyadenylate-binding protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1900.10">
        <property type="entry name" value="c-terminal domain of poly(a) binding protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036053">
        <property type="entry name" value="PABP-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006515">
        <property type="entry name" value="PABP_1234"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002004">
        <property type="entry name" value="PABP_HYD_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034364">
        <property type="entry name" value="PABP_RRM1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045305">
        <property type="entry name" value="RRM2_I_PABPs"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003954">
        <property type="entry name" value="RRM_euk-type"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01628">
        <property type="entry name" value="PABP-1234"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24012">
        <property type="entry name" value="RNA BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00658">
        <property type="entry name" value="MLLE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00517">
        <property type="entry name" value="PolyA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00361">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63570">
        <property type="entry name" value="PABC (PABP) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51309">
        <property type="entry name" value="PABC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 13" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="8" id="KW-0509">mRNA transport</keyword>
    <keyword evidence="11" id="KW-0539">Nucleus</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0677">Repeat</keyword>
    <keyword evidence="10 12 13" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="9" id="KW-0810">Translation regulation</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="domain" description="RRM" evidence="15">
        <location>
            <begin position="38"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="15">
        <location>
            <begin position="126"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="15">
        <location>
            <begin position="219"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="15">
        <location>
            <begin position="322"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="domain" description="PABC" evidence="16">
        <location>
            <begin position="517"/>
            <end position="594"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="461"/>
            <end position="517"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="14">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="14">
        <location>
            <begin position="488"/>
            <end position="504"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022816"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022845"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU362004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS51309"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="OBZ91397.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="598" mass="67041" checksum="8DE3AE490A16CBB5" modified="2016-11-30" version="1">MSTPSAENTGTSAMPEQFQQPPQQPQSGGISSTGAPSASLYVGELDPSVTEAMLFEMFNMVGPVASIRVCRDAVTRRSLGYAYVNFHNFADAERALESLNYSLVKGRACRIMWSQRDPALRKTGNGNIFIKNLDSTIDTKALHDTFSAFGNILSCKIARDDEGKSKGYGFVHYETEEAADKAIKHVNGMLLNDRKVFVGHHISRKERQSKLEEVRAHFTNVYVKNLSDDVTDEQLAELFNQYGKTTSAIISRDEDGRSRGFGFVNFEDHDEAATAVDQLNETEFHGQQLYVSRAQKKTEREEELRRQYEQAKLEKLNKYQGVNLYVKNLDDDMDDNRLRQEFSIYGAITSAKVMRDEKTDASRGFGFVCFSSPEEATRAVTEMNGRMLGSKPVYVALAQRKEVRRSHLEAQMTQRSQMHGMGMPGAAGGYMPPGAPLFYAPPGNAFIPQAGQRPMFPQGQMMPRPRWAQQQPYPQGMAHPGYPPMPRPPREPRPPKVQKDHNEAQEEEPVGNQTNNVNTLTASDLESVSPEAQKQMIGERLYPLINEQEPEYAGKITGMLLEMDNMELLRLLGDKASLHSKIEEAVDVLKQHLANTSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NQW3</accession>
    <name>A0A1C7NQW3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Nuclear pore complex protein Nup85</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">nup85</name>
        <name evidence="10" type="ORF">A0J61_00430</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Functions as a component of the nuclear pore complex (NPC).</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Component of the nuclear pore complex (NPC).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Nucleus</location>
            <location evidence="1 9">Nuclear pore complex</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the nucleoporin Nup85 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000009">
        <property type="protein sequence ID" value="OBZ91517.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NQW3"/>
    <dbReference type="STRING" id="101091.A0A1C7NQW3"/>
    <dbReference type="InParanoid" id="A0A1C7NQW3"/>
    <dbReference type="OrthoDB" id="17644at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031965">
        <property type="term" value="C:nuclear membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031080">
        <property type="term" value="C:nuclear pore outer ring"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017056">
        <property type="term" value="F:structural constituent of nuclear pore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006406">
        <property type="term" value="P:mRNA export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045893">
        <property type="term" value="P:positive regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006606">
        <property type="term" value="P:protein import into nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011502">
        <property type="entry name" value="Nucleoporin_Nup85"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13373">
        <property type="entry name" value="FROUNT PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13373:SF21">
        <property type="entry name" value="NUCLEAR PORE COMPLEX PROTEIN NUP85"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07575">
        <property type="entry name" value="Nucleopor_Nup85"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 9" id="KW-0509">mRNA transport</keyword>
    <keyword evidence="7 9" id="KW-0906">Nuclear pore complex</keyword>
    <keyword evidence="8 9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5 9" id="KW-0653">Protein transport</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 9" id="KW-0811">Translocation</keyword>
    <keyword evidence="3 9" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004567"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005573"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022816"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023132"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU365073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OBZ91517.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="592" mass="68640" checksum="BF11D5C05E82B67C" modified="2016-11-30" version="1">MSDTNSTHTPDLDDKISNVDLLSQKLNDLQTKNLTKEQLYRDSFKTFNKINNMIRSHAVFDHADHRENIEAIAEYSDKVHDCLETKHLEPIWELAESLYFPLYPHSTAADLAGELSGWLDQYYPLPEDNVDWICTLRHLLRGNTAMALNGLESIKQESQQSELDRMLGPLIQLIEQYNSLSATNTTGYINTWQQWQEACKTHYQKFSDICQTNEVDVDNDSIYWCHLIYQTLIGEEMHQLDDDVLLMEQLVAILLYSRPYMKPTSLQYTAQQIENCDSDDQLLTIADYLLKGLLDDALDCSDDLWLQTHLGQALIASGAYPIHQLTSATAEDGVALDPVFYCIQQYAHWIADTYDMWTEAFVYLTFCQENQALWVQQLLGKDEAHLSIPWEYVDKVLSLAIEYNLKPVEQFVYRAIGKHEEAQENRRQATVAYGKAQDWTSVDRLAEAALKRYQKTGQLDSVVMDMESLHQSQPYSFLIRYQQLKDTMTQKAWEEAAQLLWALLKDEHIPPKYSIVLLIDNRSILKDPKHHFYQLDQLVEWIRLFNQIKLDTAAFSFIQHYYNMTQQTQLTTDIILAQLREQLAFKAATAPC</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NR05</accession>
    <name>A0A1C7NR05_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Gamma-secretase subunit PEN-2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">psenen</name>
        <name evidence="8" type="ORF">A0J61_01119</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the PEN-2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000032">
        <property type="protein sequence ID" value="OBZ90846.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NR05"/>
    <dbReference type="STRING" id="101091.A0A1C7NR05"/>
    <dbReference type="InParanoid" id="A0A1C7NR05"/>
    <dbReference type="OrthoDB" id="524898at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070765">
        <property type="term" value="C:gamma-secretase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019379">
        <property type="entry name" value="Gamma_Secretase_Asp_P_PEN2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16318">
        <property type="entry name" value="GAMMA-SECRETASE SUBUNIT PEN-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16318:SF0">
        <property type="entry name" value="GAMMA-SECRETASE SUBUNIT PEN-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10251">
        <property type="entry name" value="PEN-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0914">Notch signaling pathway</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="20"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="54"/>
            <end position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009607"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022976"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OBZ90846.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="98" mass="11373" checksum="5439DEC2B2899CDA" modified="2016-11-30" version="1">MAALEKMSSQEHIAISRKMFYGGFAFLPLLWLVNFLYFYKQSQKTDAPKELKRYIYLSLGGCVVWFVVLTTWYGLFVNKRIDWGQGADRITVVIPKGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NSA0</accession>
    <name>A0A1C7NSA0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Putative pyrimidine permease RutG</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">rutG_1</name>
        <name evidence="8" type="ORF">A0J61_00653</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000015">
        <property type="protein sequence ID" value="OBZ91316.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NSA0"/>
    <dbReference type="STRING" id="101091.A0A1C7NSA0"/>
    <dbReference type="InParanoid" id="A0A1C7NSA0"/>
    <dbReference type="OrthoDB" id="1641903at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042907">
        <property type="term" value="F:xanthine transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006043">
        <property type="entry name" value="NCS2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42810">
        <property type="entry name" value="PURINE PERMEASE C1399.01C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42810:SF4">
        <property type="entry name" value="URIC ACID TRANSPORTER UACT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00860">
        <property type="entry name" value="Xan_ur_permease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="104"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="162"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="193"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="225"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="250"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="372"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="404"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="438"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="511"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008821"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OBZ91316.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="511" mass="55939" checksum="AD750EA06615597A" modified="2016-11-30" version="1" fragment="single">MNSSIHIIKKQSIMSDATDLETSLNEHNDTFRSVCRQHGLRKAVAFSIIHYFPHYAHNNSGSIQIEERPSWLQCVTYGIQHVLAMFSNVVVILRYKLKHLQHRLKIAIASILFSGISTLLFFITTAGRVPSYLGCSGSFIGSILAVSGYTRTGNSSFNQNTAPVQGAIFILSLVYMAISFLVMLVGYHWLEFFMPPIVTGSIIAGIGFHLSFISYRQATSTSFDSYLAIATALIVMLISVYAPTQILKRIALLLGTIIGYFIYAMCGLKDIGPGIDYSGIVSSAWVKVPPIGTHFEFHSSAISTIMPILIVLLAENLGHMKAIGSITSRPMLKHMGRAYLGDAVGCLLTSLGGTLPSTTYAENIGVLSVTRVFSPLVIVFAALFAILLGFFAKFNAVVRSIPDGVLAGVMFVLYALIAMTGIRIWVASRIDFNNSQNIFIGGIPVLIAVVLQTPVQLGNFQLDGIGAATFGAIILNQLLQGYDGMKRCYPYIRKLKTFFSDKLRRFSLPRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NW46</accession>
    <name>A0A1C7NW46_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Denticleless</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">dtl</name>
        <name evidence="7" type="ORF">A0J61_00310</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the WD repeat cdt2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000006">
        <property type="protein sequence ID" value="OBZ91664.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NW46"/>
    <dbReference type="FunCoup" id="A0A1C7NW46">
        <property type="interactions" value="244"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NW46"/>
    <dbReference type="InParanoid" id="A0A1C7NW46"/>
    <dbReference type="OrthoDB" id="2096344at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030674">
        <property type="term" value="F:protein-macromolecule adaptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043161">
        <property type="term" value="P:proteasome-mediated ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051865">
        <property type="entry name" value="WD-repeat_CDT2_adapter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22852:SF0">
        <property type="entry name" value="DENTICLELESS PROTEIN HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22852">
        <property type="entry name" value="LETHAL 2 DENTICLELESS PROTEIN RETINOIC ACID-REGULATED NUCLEAR MATRIX-ASSOCIATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="2 6" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="120"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="162"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="262"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="383"/>
            <end position="419"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038344"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OBZ91664.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="419" mass="48192" checksum="7FE561A5E776044A" modified="2016-11-30" version="1">MQSSSLKRKNSQLLSKEPSCSKYNVYRSLKQRSLGHPRLFGRQVKVSARPLLSHFMSPPEMVYQFVYSESSEFCSPLYCDFAHHRNDGNLLAVSDEDGRVSLLRTDKNNDINNYEFHEFFKCHQHAISDIKWSTDDRVLATASHDRTVRLWDPNTRTLLAKYDGHEDIVKSIHWHPTNSDLLVTSSKDGSFRVWDAREQQRENEQEIDDSTRVKVCKPTLTVSEAHQGQEPQTRKRKNGPQPLVIRSVTCALYMHTDETKIISSGSSDGSIKLWDLRAKRSPAVLSSTTFVTESGKLSGVTDLKIDSTGTRLFSSCMDNRIYMHYLSDLSKPACYFRHPDYKVGTFDIKICLSPDDRFLASGSFDKHCFVWDTKEPERDAYLFEGHTRKVTGVSWNKYSLDQFATCSEDYTTRIWSLDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-06-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MTV3</accession>
    <name>A0A1C7MTV3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_11688</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01002346">
        <property type="protein sequence ID" value="OBZ80263.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MTV3"/>
    <dbReference type="InParanoid" id="A0A1C7MTV3"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="10"/>
            <end position="41"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ80263.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="63" mass="7741" checksum="8E1D0568F0AFED99" modified="2016-11-30" version="1">MFRIEPLQPNQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQIPFIFQHAINPAIHIELLLNID</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MUF6</accession>
    <name>A0A1C7MUF6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_11522</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01002144">
        <property type="protein sequence ID" value="OBZ80428.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MUF6"/>
    <dbReference type="InParanoid" id="A0A1C7MUF6"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="43"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ80428.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="43" mass="4746" checksum="4AF63B84B1711762" modified="2016-11-30" version="1" fragment="single">MFISQNSKSKRDQGSESSKGKQPIEGLRTTVSEKNVPDHLSTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MUI0</accession>
    <name>A0A1C7MUI0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">A0J61_11481</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01002090">
        <property type="protein sequence ID" value="OBZ80470.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MUI0"/>
    <dbReference type="STRING" id="101091.A0A1C7MUI0"/>
    <dbReference type="InParanoid" id="A0A1C7MUI0"/>
    <dbReference type="OrthoDB" id="1882547at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006004">
        <property type="term" value="P:fucose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11340">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11350">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019378">
        <property type="entry name" value="GDP-Fuc_O-FucTrfase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36050">
        <property type="entry name" value="O-FUCOSYLTRANSFERASE 30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36050:SF1">
        <property type="entry name" value="O-FUCOSYLTRANSFERASE 30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10250">
        <property type="entry name" value="O-FucT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="2" id="KW-0294">Fucose metabolism</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008889318" evidence="4">
        <location>
            <begin position="29"/>
            <end position="467"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023253"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OBZ80470.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="467" mass="53557" checksum="85EF2FD16A52B8CF" modified="2016-11-30" version="1">MMRSMRFVWATCLSVLVLTLFLVTYTSTQSMSVQLKFNITPLTQQQKAKNSEKYITFLPHSGLHNQRIGLLNALLLAKSLNRTLILPEINIGTAVWWRPNTLAEFRLSECPQLGVEGHANCKDFKKYVPVSVESIFDLSAAHAQGIRTIQRSSMSQDYFKDVMGLKDPEDIYRLQDNSRYSYRIYDSEDNQDDIRTFAQRVEMNDLRQLDQKVIMFGSLHYTLRVAYQDPAMIWLANHLREEISIAHPVVIRQALSVIPLLGGPETFVGVHLRQGDGYFKALMDETVNTLRATLEQPELTQEQIIAQQQSLEPVPFQATPLTMEDETKIAILKSLSADNRDLLNQCVAWHSQENHPRLRLIFMATDTPQPRTTLKDLYDEFPCIFTLSDFPEVIESTLSMSPMLTGHAMVDEEMKRLDTTIASLLFPMIDAEIASHGSIFIGTRKSTFSQYINFRYNRFQSMYHTLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MV27</accession>
    <name>A0A1C7MV27_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_11332</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001917">
        <property type="protein sequence ID" value="OBZ80618.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MV27"/>
    <dbReference type="InParanoid" id="A0A1C7MV27"/>
    <dbReference type="OrthoDB" id="2281104at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="44"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ80618.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="44" mass="4910" checksum="F8B0CBBF5D347363" modified="2016-11-30" version="1" fragment="single">MLIQNLHVSSGWVNGTIAQVKEIEKENVLLSKEGPDGDEMTLWV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MW80</accession>
    <name>A0A1C7MW80_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Small ribosomal subunit protein uS5</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">40S ribosomal protein S2</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">rps2_1</name>
        <name evidence="8" type="ORF">A0J61_11244</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001819">
        <property type="protein sequence ID" value="OBZ80706.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MW80"/>
    <dbReference type="STRING" id="101091.A0A1C7MW80"/>
    <dbReference type="InParanoid" id="A0A1C7MW80"/>
    <dbReference type="OrthoDB" id="10253125at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022627">
        <property type="term" value="C:cytosolic small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.20:FF:000002">
        <property type="entry name" value="40S ribosomal protein S2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000851">
        <property type="entry name" value="Ribosomal_uS5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005711">
        <property type="entry name" value="Ribosomal_uS5_euk/arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013810">
        <property type="entry name" value="Ribosomal_uS5_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018192">
        <property type="entry name" value="Ribosomal_uS5_N_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01020">
        <property type="entry name" value="uS5_euk_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13718:SF4">
        <property type="entry name" value="40S RIBOSOMAL PROTEIN S2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13718">
        <property type="entry name" value="RIBOSOMAL S SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00333">
        <property type="entry name" value="Ribosomal_S5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54768">
        <property type="entry name" value="dsRNA-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00585">
        <property type="entry name" value="RIBOSOMAL_S5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50881">
        <property type="entry name" value="S5_DSRBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="1 5 8" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="S5 DRBM" evidence="7">
        <location>
            <begin position="76"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="16"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="152"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00035255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00035407"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OBZ80706.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="152" mass="16858" checksum="807F71EF0FDE134A" modified="2016-11-30" version="1" fragment="single">MADSAPADRRGNFGRGRGRGGPRRGGRRGEEKNEWVPVTKLGRLVKANKIKSIEEIYLFSLPIKEYQIVDYFLPKLTDQVMKIMPVQKQTTAGQRTRFKAFVVIGDENGHVGLGVKCAKEVATAIRGGIILAKLSIIPVRRGYWGSNLGEPH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MWH2</accession>
    <name>A0A1C7MWH2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">CCHC-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">A0J61_10823</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001421">
        <property type="protein sequence ID" value="OBZ81128.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MWH2"/>
    <dbReference type="STRING" id="101091.A0A1C7MWH2"/>
    <dbReference type="InParanoid" id="A0A1C7MWH2"/>
    <dbReference type="OrthoDB" id="2211282at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00303">
        <property type="entry name" value="retropepsin_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.70.10">
        <property type="entry name" value="Acid Proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021109">
        <property type="entry name" value="Peptidase_aspartic_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001878">
        <property type="entry name" value="Znf_CCHC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13975">
        <property type="entry name" value="gag-asp_proteas"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50630">
        <property type="entry name" value="Acid proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50158">
        <property type="entry name" value="ZF_CCHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="CCHC-type" evidence="3">
        <location>
            <begin position="250"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="208"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="464"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="208"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="470"/>
            <end position="489"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OBZ81128.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="570" mass="62137" checksum="B4014C62B70E8475" modified="2016-11-30" version="1">MTTHNEENIISALNQIVTQNRYAALQSMRLIYNYVPGTNIELWLRIFHQRGKHLGLDDGMLVDQLPSYLPVDMAQWILSSLTLDTWTKVKKALTETYGIPVAAQKQMCREKLEALQQGNTPSRQFKARFQMILQELPEGVSLPAEQTRSIYLCVMNQHLAVKICGFVSSSWDWSKVANKAIEVEDMLTADHRLAALYLQNTQSPASIPTVPLQQPGSALASNLGPAPMGRQDDKRKDRFNQWVRPGVPLCGHCGKEGHLSKRCRSTRCERVNAMAVQGTTPVAPTSTDTAWAPFSHTEVGSDSYHTTVNYAVVPEASDTAAPTVTSTETVDAAHTLCYLSQKVDYREGFTLNCSILGTDTQCLIDSGATFSAISIRLAEQLKLPLDKSQKLCFTTATGVDAWTHGTTDVQVMLNGTLVNLHCHVVEDLAYPIIAGVKGLKANKAFVDFATYSIKFPGSPDWFPLGRSPGEDSSGSGSTLQVHSGNSGSSGDAPLVSPGSVVKAPKRYLDKPNDCHLVDTLLLPGHHHAYCTISGHRNTLAMVTTPTDLAAEKLIAVAAGIVQFDNYGHAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MWH7</accession>
    <name>A0A1C7MWH7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_11145</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001713">
        <property type="protein sequence ID" value="OBZ80806.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MWH7"/>
    <dbReference type="STRING" id="101091.A0A1C7MWH7"/>
    <dbReference type="InParanoid" id="A0A1C7MWH7"/>
    <dbReference type="OrthoDB" id="2289822at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ80806.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="243" mass="27355" checksum="E4831DA0FD21422E" modified="2016-11-30" version="1">MIQVAIFPRKPYDLSSFLRPLIAEVNQLYSRGLIIKKGDEVKYDGSVAIFGFTGEIPGIAQLINFVEHTGTYGYKICLAVADLHTEHVRHGQYFSTEAAERTMESLLQGDEDPGIGGIPQLIGSLETFLGVYSFFGDELHMLGHGINRWIDDSKPTTPTVFDFSFDHKKHFFRAVEWQHVLLHVAPTIIAPYLKQNVATDALMDLVNACSISLQRSISPSELTYMESAFGRWGDFLRREIRAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MWI9</accession>
    <name>A0A1C7MWI9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_10774</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001383">
        <property type="protein sequence ID" value="OBZ81177.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MWI9"/>
    <dbReference type="STRING" id="101091.A0A1C7MWI9"/>
    <dbReference type="InParanoid" id="A0A1C7MWI9"/>
    <dbReference type="OrthoDB" id="2287989at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="146"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ81177.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="146" mass="16320" checksum="E0F618D793D95365" modified="2016-11-30" version="1" fragment="single">MSISPSRIVYNLANIETALVSTEVPGVSSLPLNDTICVVANEWKECFDRISELSASKWIKKRSRSAENLIMGETRECHRRGQHTPTRTVRISQKDSKKIGCKGTLSILQYVENPDVVEIKMSMGHVNHVPGSNSDIRTLPLTRETV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MWR0</accession>
    <name>A0A1C7MWR0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_11071</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001645">
        <property type="protein sequence ID" value="OBZ80879.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MWR0"/>
    <dbReference type="InParanoid" id="A0A1C7MWR0"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="27"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ80879.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="80" mass="8915" checksum="C47E5D101E223ED3" modified="2016-11-30" version="1" fragment="single">MVAKQNELIATVNLCLDKLNRLEAREGHELHQQANSSGPVGTSDVPIYRPQISGSSDNKLKQKLNHFIQQWLGDAVIVNH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MX97</accession>
    <name>A0A1C7MX97_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_10494</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001200">
        <property type="protein sequence ID" value="OBZ81457.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MX97"/>
    <dbReference type="InParanoid" id="A0A1C7MX97"/>
    <dbReference type="OrthoDB" id="2269660at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="31"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="58"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="123"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="151"/>
            <end position="171"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ81457.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="198" mass="22544" checksum="9E2BAC163A8B6A33" modified="2016-11-30" version="1">MSIQFLTSKVIHTNILLICLYRYASRQQTHYSMLIGILSAILPAIIIILGYITPSNTLHLSLSIMLMILLSYIGYHMVQSSKQTLDKQFKLDISLILLCPVYLVKQTLDSVPKSMIDEPWEVIVAHLISSLVLAVVFSMTMWYAAPWCQQCVYSIMIYWTAAIQCAEWIGYLELIHNPSYASLIFIIRSNATPTHRLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MXD7</accession>
    <name>A0A1C7MXD7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Putative cinnamyl alcohol dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">CAD1</name>
        <name evidence="4" type="ORF">A0J61_10529</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001218">
        <property type="protein sequence ID" value="OBZ81421.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MXD7"/>
    <dbReference type="STRING" id="101091.A0A1C7MXD7"/>
    <dbReference type="InParanoid" id="A0A1C7MXD7"/>
    <dbReference type="OrthoDB" id="1879366at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016616">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047109">
        <property type="entry name" value="CAD-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42683">
        <property type="entry name" value="ALDEHYDE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OBZ81421.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="93" mass="10567" checksum="196D293C578437A9" modified="2016-11-30" version="1" fragment="single">EKYLTLIRANGHFLNVNLPDWKFPPLSPLVLTFGQVNISGSLIGSPKEIEEMLAFAAEKNIRPWITVLPMKDVNKAIEDFNAGKPRFRFVLEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MXM7</accession>
    <name>A0A1C7MXM7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">MFS antiporter QDR2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">QDR2_2</name>
        <name evidence="7" type="ORF">A0J61_10380</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001145">
        <property type="protein sequence ID" value="OBZ81570.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MXM7"/>
    <dbReference type="STRING" id="101091.A0A1C7MXM7"/>
    <dbReference type="InParanoid" id="A0A1C7MXM7"/>
    <dbReference type="OrthoDB" id="3936150at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502:SF5">
        <property type="entry name" value="QUINIDINE RESISTANCE PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="44"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="78"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="110"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="200"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="288"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="326"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="368"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="397"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="435"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="461"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="6">
        <location>
            <begin position="44"/>
            <end position="487"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OBZ81570.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="495" mass="54326" checksum="87050EB6F3823FDB" modified="2016-11-30" version="1">MQEKTVDTNANGSRIRSYFRERMALKPPVLEDPRLLDPKIKSGIVACISLVACTGGFSSTIYFPGIPYVTADLNAPPIATTLTAALFILFMGIMPVVWASISEHFHVRRIIFLVAMVIYSASSLGAAFVQNIWVLVVLRCIQSMGVSSGQSVGSGYISDLYPIEQRGAAFGKYMFGAVFGPLLGPILGGLLTMSSMGWRATFWFCFSFGIFIFIITFLFTPETFRDEAKFEQQLPIFEKDSNSQLSTRTTVSDVPDTKTIDNNDIDKEVLPKKRFNPFKPFGLLRHPFIFMVALTGGFFFGAMFATETILPSAFEKTYGLNSWQTGLCYLGAGIGNICGTFVGGRLSDRLLLRSRRLRGGIPRCEDRLTANIWAAGLFCVPLGCLIFGWVVEYKLSFWGAIVGFGIQCFGNMQVMSTCTAYLVDAVPGRGSSVTAATGFVRMTLSCVLTVVATPMVQALGAGWTCTLFACLSWVGMLLLFILKIYGEPIRSWSGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MYP5</accession>
    <name>A0A1C7MYP5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Protein csx2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">csx2_1</name>
        <name evidence="8" type="ORF">A0J61_09982</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000991">
        <property type="protein sequence ID" value="OBZ81970.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MYP5"/>
    <dbReference type="FunCoup" id="A0A1C7MYP5">
        <property type="interactions" value="231"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7MYP5"/>
    <dbReference type="InParanoid" id="A0A1C7MYP5"/>
    <dbReference type="OrthoDB" id="10266696at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd08204">
        <property type="entry name" value="ArfGap"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.29.30:FF:000252">
        <property type="entry name" value="ARF GTPase activator (Csx2)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.220.150:FF:000017">
        <property type="entry name" value="ARF GTPase activator (Csx2), putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.220.150">
        <property type="entry name" value="Arf GTPase activating protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.60">
        <property type="entry name" value="Arfaptin homology (AH) domain/BAR domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045258">
        <property type="entry name" value="ACAP1/2/3-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027267">
        <property type="entry name" value="AH/BAR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037278">
        <property type="entry name" value="ARFGAP/RecO"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001164">
        <property type="entry name" value="ArfGAP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038508">
        <property type="entry name" value="ArfGAP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004148">
        <property type="entry name" value="BAR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001849">
        <property type="entry name" value="PH_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23180:SF160">
        <property type="entry name" value="ADP-RIBOSYLATION FACTOR GTPASE-ACTIVATING PROTEIN EFFECTOR PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23180">
        <property type="entry name" value="CENTAURIN/ARF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01412">
        <property type="entry name" value="ArfGap"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16746">
        <property type="entry name" value="BAR_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00169">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00405">
        <property type="entry name" value="REVINTRACTNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00105">
        <property type="entry name" value="ArfGap"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00233">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57863">
        <property type="entry name" value="ArfGap/RecO-like zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103657">
        <property type="entry name" value="BAR/IMD domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50115">
        <property type="entry name" value="ARFGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50003">
        <property type="entry name" value="PH_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="PH" evidence="6">
        <location>
            <begin position="402"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="domain" description="Arf-GAP" evidence="7">
        <location>
            <begin position="597"/>
            <end position="721"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="304"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="312"/>
            <end position="362"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50115"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OBZ81970.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="908" mass="102421" checksum="80AABA15D35769E5" modified="2016-11-30" version="1">MTEYVSQVDNFSPPIKPLTTKSSEQKGQVVDLEDGPLFRATIKEYESRTSVLKGYLKRILKQASATLDAKQALLEQDKLFIEALREAPFTEPLFSHYLDATWNKLHEQQERLAVCMQNLLIIPLQKLYDMDIKAVDAKSRQFEDVSKDYYSNLSKYLSIKTPGTQHWASIPTQQIQQLTSLTNTNSQQDLKEKRKQKAETEFRVKKSEFDLVRFDYYQFLTDLHGGKKEQEILYHLLNHYEKEYAYHQAVLKTLEPHKGGLDQLATIIAEASREQKIVNQERDEKRKILVSRYSTPVIQIDDSEKRRSFLGSSTSPSAPLPQPSTSSTSSTSTSPPVLPPISLNSNILSISPPPHSSQLHSPPFLPPTEQQRVGLGISQMESKFKGIRDLEQQDPAFKDHIGRRKEGFLFATSKPSKNHHHTPSTFDMSSTVNWHKYWCVLSCGQLHEYSNWKKQLESHIEPINLRFATVREARNVDRRFCFEVITPSFRRMYQATSEEELISWMATINNAISSLLNGMSSAIDLPVSSSSKKSNGHWKHTRSFSGALSGLAAATKDKYLKKRNLSTSSASTMQKPLVISLPLDESMSQAHCPLSSDDLLSALRKDLSNTICADCSAKDPDWCSLNLGILICIECSGIHRSLGTHISKVRSLTLDSASFTPDIVQLLLSIGNAKSNDISEAQLSTSQVVKPVATDTREMKLKYIQQKYLDRALVKDTTMDPMHLLYEAIEQDSIPMAMEAIALGANVNQPLEKINWIVPLLSLQRHPEKTIEVASPVARTSDGDPSVLKLPMLDVNGNEYLDRTVDVLLSPDQQPFTVRYAIHFALLNHPHLNPIESNHRLFPMAEFLFQNGADVFIVDECSGRLLADLIGVGELVDDEAIHYLNMKNSLRGQSTIVRRQTIPPPYAY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MZ32</accession>
    <name>A0A1C7MZ32_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">AB hydrolase superfamily protein C4A8.06c</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">A0J61_10282</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the 'GDXG' lipolytic enzyme family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001102">
        <property type="protein sequence ID" value="OBZ81669.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MZ32"/>
    <dbReference type="STRING" id="101091.A0A1C7MZ32"/>
    <dbReference type="InParanoid" id="A0A1C7MZ32"/>
    <dbReference type="OrthoDB" id="408631at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013094">
        <property type="entry name" value="AB_hydrolase_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050300">
        <property type="entry name" value="GDXG_lipolytic_enzyme"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033140">
        <property type="entry name" value="Lipase_GDXG_put_SER_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48081">
        <property type="entry name" value="AB HYDROLASE SUPERFAMILY PROTEIN C4A8.06C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48081:SF19">
        <property type="entry name" value="AB HYDROLASE SUPERFAMILY PROTEIN C4A8.06C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07859">
        <property type="entry name" value="Abhydrolase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01174">
        <property type="entry name" value="LIPASE_GDXG_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Alpha/beta hydrolase fold-3" evidence="4">
        <location>
            <begin position="200"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="active site" evidence="3">
        <location>
            <position position="281"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010515"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10038"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF07859"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OBZ81669.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="588" mass="65686" checksum="6623FAB7883C9449" modified="2016-11-30" version="1">MLPKGLKKIVTVKGKPLNYPSDSGSFTSSLNNKHFTSSSAALNSSNSMEKTEQHHHSTPIADSFLWAHLIPPVPIIASTMYRHYAKGPPAKSWTLTTELTIAVIRDFLQRSSKLKVEDLQKLSTNKKLPIPPNIKRTKFTVPNEYRKRAGDLISKQLSHSDQQRIAWNWEKDRENAAPIKGEWLQAKGNPLDPCKESTTFYLHGGAYYLACYGLYRQFLSKIIKYSKGRTCAIDYRLAPQHPFPAAVEDALATYLYLIDPPKDSEHMQPVDPKKIVVAGDSAGGGLTMALLIAIRDAGLPAPAGAMALSPWMDLTHSLPSILSNMMTDYLPPTGFKHAPSAALDYAQLPAREQDVDILEKIDEEVKGDLKEKEQVNRVSIGPFSEAVPINGSDLHRVQFYANNDALKIPMVSPIFDKKCLRGLPKLLIQCGTAERLRDESIFSAFQASNTSPLPINNERYGQDTKVALEMYKDQPHVFQLLFSNKGTTQAMKNLGAFVRDVTGSPAPFDYKREKHSPGYVTDEKLTVKSISTDGQTTDIKQELLNQLTPEVWKDWVDRLARPSLKQRMDEVSVAYDKHISKIVANTQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MZ36</accession>
    <name>A0A1C7MZ36_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_09922</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000972">
        <property type="protein sequence ID" value="OBZ82031.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7MZ36"/>
    <dbReference type="InParanoid" id="A0A1C7MZ36"/>
    <dbReference type="OrthoDB" id="2258247at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="35"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="38"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="210"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ82031.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="210" mass="23334" checksum="7AABD503090CB657" modified="2016-11-30" version="1" fragment="single">MASSAINHKGIFQTPIPYQTNQKSWVAIVNEGIKRTSSRTPDPSTARPSAEPGQLTESAVRDVYRHVARPFLKGTVSNSLLIDITTIRDVKVFVQELHEVCNGSEHLWSVSSTLRRDFSRVYAEIVVSPSKYIQFAQEGFELKTQGKFLAFPSLSPSAEVLKISLXGLPSQYGRRQGGLDQLRTDMNHNLRHYGKIIDSGLVTNSSGVYT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MZ54</accession>
    <name>A0A1C7MZ54_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Reverse transcriptase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_10262</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001091">
        <property type="protein sequence ID" value="OBZ81689.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MZ54"/>
    <dbReference type="STRING" id="101091.A0A1C7MZ54"/>
    <dbReference type="InParanoid" id="A0A1C7MZ54"/>
    <dbReference type="OrthoDB" id="2417874at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000477">
        <property type="entry name" value="RT_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33116">
        <property type="entry name" value="REVERSE TRANSCRIPTASE ZINC-BINDING DOMAIN-CONTAINING PROTEIN-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33116:SF84">
        <property type="entry name" value="RNA-DIRECTED DNA POLYMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00078">
        <property type="entry name" value="RVT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Reverse transcriptase" evidence="1">
        <location>
            <begin position="19"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="271"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ81689.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="271" mass="31432" checksum="56997CD2E47F7B66" modified="2016-11-30" version="1" fragment="single">PLLLSIVQDPAYKGYISVHQDQRQQIKCLAYADDICVFVKDREDFSRLQIHLQAYGAVSNARFNQHKTEAFALDGRVSPTWQSILQEHRISQYYHASSPSAFRYLGFYICYTVAQRQSVESMLLEKIKTQIQVFSSRSLSFRGRASVANTLILSKLWFTLRILNPPKRFFVKVRSLIYSFVWQKKYPLVAFNQLCLPYTSGGVGLLEPSRQHMLFQVKWRVSLFDRRADRLTVAALEHHLSFLSPISGVTLLALFEPTFRSHHTSIRLFHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MZ84</accession>
    <name>A0A1C7MZ84_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">C2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_09858</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000956">
        <property type="protein sequence ID" value="OBZ82092.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MZ84"/>
    <dbReference type="STRING" id="101091.A0A1C7MZ84"/>
    <dbReference type="InParanoid" id="A0A1C7MZ84"/>
    <dbReference type="OrthoDB" id="270970at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.150">
        <property type="entry name" value="C2 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000008">
        <property type="entry name" value="C2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035892">
        <property type="entry name" value="C2_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052981">
        <property type="entry name" value="Ingression_C2_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47052">
        <property type="entry name" value="CONSERVED SERINE PROLINE-RICH PROTEIN (AFU_ORTHOLOGUE AFUA_2G01790)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47052:SF3">
        <property type="entry name" value="INGRESSION PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00168">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49562">
        <property type="entry name" value="C2 domain (Calcium/lipid-binding domain, CaLB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50004">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="C2" evidence="2">
        <location>
            <begin position="1"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="121"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="269"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="155"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="188"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="223"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="269"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="282"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="307"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="334"/>
            <end position="396"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ82092.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="402" mass="43964" checksum="5474E80F6F7B78EA" modified="2016-11-30" version="1">MPAGTLTFTPLTIAGLAQNGYAESRAFIGCYVSSNEKHRTNSADGPEPQFRDVLKLNVNEGDQALHIDVVNEDQSRPGLIGTTQVQLGKVFESGKFEDWVPLSSAQGAPLGHIFMKLDFQSEGAPQGHPSERQNSSSLGPQTPLPNQYGAGQAPSFPQHQPVSYGSDSSFGKPSNDSEQRSAAGGYYGNNQASYGGNQANYAQPPAYNSPMGGAPPSMASPGTPGTPTSAASTEKKKKMNPDWMKYGGAALAGAAAVGLGTWIKHEIDEDEEEAREEELEQREETIRQTEHRLAELEREDIREHGHNTNPYSFSTEETPRGFGDLNEEVQVAEPEPEPEQEEEEAEEEAEEEAEEEAEEEAEEEAEEEEEAEEEAEEEEEAEEEAEEEAEEEEPEVDDSKWI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MZP0</accession>
    <name>A0A1C7MZP0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_11347</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001933">
        <property type="protein sequence ID" value="OBZ80604.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MZP0"/>
    <dbReference type="STRING" id="101091.A0A1C7MZP0"/>
    <dbReference type="InParanoid" id="A0A1C7MZP0"/>
    <dbReference type="OrthoDB" id="2278185at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ80604.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="149" mass="17194" checksum="48B72AAE04C9DE18" modified="2016-11-30" version="1">MTNEYEEIVHQVLVPLKALSYLKHSFENMREAYFDYRHQMPVAFFTDNVKGNQSFAEGIFESLKEGVEPADLERMNTLSTDSSTYLQLPSEINVLYLCRDFDTMEISLRSLLEEIKPPTEDGSDVAKGFDREWDICYSEGVDSCRVDVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MZP1</accession>
    <name>A0A1C7MZP1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_09658</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000903">
        <property type="protein sequence ID" value="OBZ82293.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MZP1"/>
    <dbReference type="InParanoid" id="A0A1C7MZP1"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="36"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="41"/>
            <end position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ82293.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="65" mass="7498" checksum="C0D347789921B353" modified="2016-11-30" version="1">MAISHLRLALFHQMLTKKSSYANVFDKAKFDAQKKKDFEENSSNNVSTRSFIIRKPKKTSSANVY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MZW1</accession>
    <name>A0A1C7MZW1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_09680</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000907">
        <property type="protein sequence ID" value="OBZ82268.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MZW1"/>
    <dbReference type="STRING" id="101091.A0A1C7MZW1"/>
    <dbReference type="InParanoid" id="A0A1C7MZW1"/>
    <dbReference type="OrthoDB" id="2873061at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35587:SF4">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35587">
        <property type="entry name" value="EXPRESSED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="32"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="44"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="59"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ82268.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="108" mass="11532" checksum="91D375B0C238957A" modified="2016-11-30" version="1">MAPTKEDKQSKLKEITESEEEMPPKKSSSKDKKSKKSKKKSKSNSLVPSDQLSELTDGVTGGGQQQSGGGGGKKDGQQPLSLRLDLNLDVEITLKARVHGDVTLALLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N062</accession>
    <name>A0A1C7N062_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">SWIM-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">A0J61_09485</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000861">
        <property type="protein sequence ID" value="OBZ82463.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N062"/>
    <dbReference type="InParanoid" id="A0A1C7N062"/>
    <dbReference type="OrthoDB" id="2287999at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007527">
        <property type="entry name" value="Znf_SWIM"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04434">
        <property type="entry name" value="SWIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50966">
        <property type="entry name" value="ZF_SWIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="SWIM-type" evidence="3">
        <location>
            <begin position="160"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="48"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="225"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="67"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="78"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="225"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="264"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="351"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00325"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OBZ82463.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="351" mass="40383" checksum="F8BC2092D94F34AE" modified="2016-11-30" version="1" fragment="single">MATRQPSNADRVVQQTPAKDGGPSLNSSTASVRGVREEVVDAKINIACSQKRAQHNQSQQAAKRRKPTVEVRESRSPDEEEESDYEGFEDQGESDYEERQYWNDRRFYRGLSDNQRRQHRALSVSESTLKRTIKHPRNYDGKNHAGEWTIQAQSSASAYYKMRVDRKDFIRSCTCPDYESRKLPCKHMYMLRQYSQDALRIHSYDSYIPGRTFVQMPEAATDIEQTNDTTNNIDNSHLPNIDRSNTSNATENHQPPNETSSVDQNHDKQVQHQESNKHESWTQMDRMLYDISTARTHQLLNDTESLFKGTNPQQFISVITKGFQETIKEYCARSNIIVQTTVSTSSHAPAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N063</accession>
    <name>A0A1C7N063_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">5'-deoxynucleotidase</fullName>
            <ecNumber evidence="7">3.1.3.89</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">SPCC4G3.17</name>
        <name evidence="11" type="ORF">A0J61_09919</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Catalyzes the dephosphorylation of the nucleoside 5'-monophosphates deoxyadenosine monophosphate (dAMP), deoxycytidine monophosphate (dCMP), deoxyguanosine monophosphate (dGMP) and deoxythymidine monophosphate (dTMP).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a 2'-deoxyribonucleoside 5'-phosphate + H2O = a 2'-deoxyribonucleoside + phosphate</text>
            <dbReference type="Rhea" id="RHEA:36167"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:18274"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:65317"/>
            <dbReference type="EC" id="3.1.3.89"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Co(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:48828"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="6">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the HDDC2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.89" evidence="7"/>
    <dbReference type="EMBL" id="LUGH01000972">
        <property type="protein sequence ID" value="OBZ82029.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N063"/>
    <dbReference type="FunCoup" id="A0A1C7N063">
        <property type="interactions" value="154"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N063"/>
    <dbReference type="InParanoid" id="A0A1C7N063"/>
    <dbReference type="OrthoDB" id="10254258at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002953">
        <property type="term" value="F:5'-deoxynucleotidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.3210.10:FF:000016">
        <property type="entry name" value="HD domain-containing protein 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3210.10">
        <property type="entry name" value="Hypothetical protein af1432"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003607">
        <property type="entry name" value="HD/PDEase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006674">
        <property type="entry name" value="HD_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039356">
        <property type="entry name" value="YfbR/HDDC2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11845">
        <property type="entry name" value="5'-DEOXYNUCLEOTIDASE HDDC2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11845:SF13">
        <property type="entry name" value="5'-DEOXYNUCLEOTIDASE HDDC2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13023">
        <property type="entry name" value="HD_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00471">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109604">
        <property type="entry name" value="HD-domain/PDEase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51831">
        <property type="entry name" value="HD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HD" evidence="10">
        <location>
            <begin position="50"/>
            <end position="153"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001638"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004074"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00009999"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00012964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51831"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="OBZ82029.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="200" mass="22961" checksum="2DA6E667BFF29B5B" modified="2016-11-30" version="1">MAQANPASVIRFLHVIENLKVWARYRATRVANRTKRTGWIDNGIQQPESIADHMHRMGIMAMLVNDPSINREKCIKMAIVHDLAEAVVGDITPHAGVSKEDKFKMEKAAMDDFKASLGHTETAEEIVSLWQEYEDASTPEALFVKDLDKFEMIVQALEYEKSDKKKLQGFFDSTHGKFQHPTVKGWAEALYREREQVWKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N0C6</accession>
    <name>A0A1C7N0C6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Protein YOP1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">reep6</name>
        <name evidence="7" type="ORF">A0J61_09417</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Membrane</location>
            <topology evidence="1 6">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the DP1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000846">
        <property type="protein sequence ID" value="OBZ82533.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N0C6"/>
    <dbReference type="FunCoup" id="A0A1C7N0C6">
        <property type="interactions" value="110"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N0C6"/>
    <dbReference type="InParanoid" id="A0A1C7N0C6"/>
    <dbReference type="OrthoDB" id="10009287at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004345">
        <property type="entry name" value="TB2_DP1_HVA22"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12300">
        <property type="entry name" value="HVA22-LIKE PROTEINS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12300:SF161">
        <property type="entry name" value="RECEPTOR EXPRESSION-ENHANCING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03134">
        <property type="entry name" value="TB2_DP1_HVA22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0675">Receptor</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="51"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="132"/>
            <end position="152"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008573"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU362006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OBZ82533.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="188" mass="22233" checksum="4FB5AC82551BB43B" modified="2016-11-30" version="1">MTTKLDQTFHQADTLNNYLNRGNQYLQRLDKELSKIEYANQLERKIGIPKSYLVAGISLFFLAFVILDRGAKILTSAMAWIYPAYASFKTIESPSRENDTQWLTYWTVIAFFHMIEYFSDILLFWFPFYYTFKIIFILWLILPQFQGAQFVYSRVLRPFLLGAQPEIERRKTKFNNTFHAATGMTKTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N1C1</accession>
    <name>A0A1C7N1C1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="18">Regulator of nonsense transcripts 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="18" type="primary">Upf1</name>
        <name evidence="18" type="ORF">A0J61_09067</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18 19">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="14">RNA-dependent helicase required for nonsense-mediated decay (NMD) of aberrant mRNAs containing premature stop codons and modulates the expression level of normal mRNAs. Also capable of unwinding double-stranded DNA and translocating on single-stranded DNA.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.12"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="12">
            <dbReference type="Rhea" id="RHEA:13066"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.13"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="13">
            <dbReference type="Rhea" id="RHEA:13066"/>
        </physiologicalReaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the DNA2/NAM7 helicase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000766">
        <property type="protein sequence ID" value="OBZ82883.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N1C1"/>
    <dbReference type="FunCoup" id="A0A1C7N1C1">
        <property type="interactions" value="1131"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N1C1"/>
    <dbReference type="InParanoid" id="A0A1C7N1C1"/>
    <dbReference type="OrthoDB" id="6513042at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003678">
        <property type="term" value="F:DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000184">
        <property type="term" value="P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd21407">
        <property type="entry name" value="1B_UPF1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18039">
        <property type="entry name" value="DEXXQc_UPF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18808">
        <property type="entry name" value="SF1_C_Upf1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd21400">
        <property type="entry name" value="ZBD_UPF1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000097">
        <property type="entry name" value="Regulator of nonsense transcripts 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.230">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.1240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045055">
        <property type="entry name" value="DNA2/NAM7-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041679">
        <property type="entry name" value="DNA2/NAM7-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041677">
        <property type="entry name" value="DNA2/NAM7_AAA_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047187">
        <property type="entry name" value="SF1_C_Upf1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040812">
        <property type="entry name" value="UPF1_1B_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018999">
        <property type="entry name" value="UPF1_CH/ZBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10887">
        <property type="entry name" value="DNA2/NAM7 HELICASE FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10887:SF364">
        <property type="entry name" value="REGULATOR OF NONSENSE TRANSCRIPTS 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13086">
        <property type="entry name" value="AAA_11"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13087">
        <property type="entry name" value="AAA_12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18141">
        <property type="entry name" value="UPF1_1B_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09416">
        <property type="entry name" value="UPF1_Zn_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51997">
        <property type="entry name" value="UPF1_CH_RICH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-0347">Helicase</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 15" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-0866">Nonsense-mediated mRNA decay</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9 15" id="KW-0862">Zinc</keyword>
    <keyword evidence="6 15" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Upf1" evidence="17">
        <location>
            <begin position="93"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="region of interest" description="C3H" evidence="15">
        <location>
            <begin position="101"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="region of interest" description="CC/SHH/C" evidence="15">
        <location>
            <begin position="115"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="region of interest" description="C4" evidence="15">
        <location>
            <begin position="161"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="1008"/>
            <end position="1031"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="16">
        <location>
            <begin position="1014"/>
            <end position="1028"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00048432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00049390"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00055561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01341"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS51997"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="OBZ82883.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="1126" mass="126633" checksum="5B14BB08B43E837E" modified="2016-11-30" version="1">MDHFEGASQDDFTFLEYSADTQSSQYEYGDFTQTPQDNTDLSLSSLHLNDTPTKKLESEQTENTTTTASTSFINDFQFEDTDDFGELIVCPEEKDLPPHACKYCGIHSPASVVKCVTCDRWFCNSRGNTSGSHIVNHLVRAKHKEVCLHPESPLGDTVLECYNCGCRNVFLLGFIPAKSDTVVVLICRQPCAAVPSSKDMTWDTTQWMPLIDDRCFLTWLVKIPTDQEQLRARQISSAQINKLEELWKDNGEATLEDLEKPGVDDEPHPVLLRYEDAYQYQNIFGPLVMMEADYDKKLKESQTCDDIVVRWDVGLNQKNIAWFYFPKLEMGEIKLAVGDELCLRYRGELHEPWSATGHVIKIPNNVSDEIALELTRANKAPTDCTHNFSVDFVWKSTSFDRMQSAMKTFAVDETSVSGYIYHRLLGHDVEPQVLKTQMPKRFSAPNLPELNHSQVYAVKSVLQKPLSLIQGPPGTGKTVTSASIVYHLAKMNPGQVLVCAPSNVAVDQLAEKIHQTGLKVVRITAKSREELDSPVSFLTLHEQVQNNDTNVELQKLIHLKRDQGELSAADEKKYKSLKRACEKEILQNADVICCTSVGAGDPRVAKLRFRTVLIDEATQASEPECMIPLVLGCKQAVLVGDHQQLGPVIMNKKAARAGLCQSLFERLVILGIRPIRLQVQYRMHPCLSEFPSNMFYEGTLQNGITTQERIRKNVDFPWPVPETPMMFYVNLGNEEISTSGTSYLNRTEASNCEKIVTRFMKSGILPSQIGVVTPYEGQRSYIVQYMQFNGSLRKDLYKEIEVASVDAFQGREKDYIILSCVRSNEHQGIGFLSDPRRLNVALTRAKYGVVILGNPKILSRHPLWHHLLVHYKEKGCLVDGALNNLRVSMIQFNRPRKAYRKDDKFRQGLAHQVDAREAFARPPLAADNRRGMNGGSGMSSMMTGGSDGRGYGQDFMQTHDPVGYIPSEMGSLPNSQFSIPFIPSASGPFTQDLSQSSVFNRKNMRQVGEDMPDSQSTYSQQTSTQQSQRYVPGSSTFANHAMGWQHMGNHTNGSSQNLYSSQTSIGLALSQSDRLRMMSEMASQNPSMSQDSIQYPYEDYKTQDVSSMMSQDFDIRSQASQSFTQF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N1J2</accession>
    <name>A0A1C7N1J2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Cytosolic endo-beta-N-acetylglucosaminidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">Engase</name>
        <name evidence="3" type="ORF">A0J61_09093</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000772">
        <property type="protein sequence ID" value="OBZ82858.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N1J2"/>
    <dbReference type="STRING" id="101091.A0A1C7N1J2"/>
    <dbReference type="InParanoid" id="A0A1C7N1J2"/>
    <dbReference type="OrthoDB" id="284473at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033925">
        <property type="term" value="F:mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd06547">
        <property type="entry name" value="GH85_ENGase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.260">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032979">
        <property type="entry name" value="ENGase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005201">
        <property type="entry name" value="TIM_ENGase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13246:SF1">
        <property type="entry name" value="CYTOSOLIC ENDO-BETA-N-ACETYLGLUCOSAMINIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13246">
        <property type="entry name" value="ENDO BETA N-ACETYLGLUCOSAMINIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03644">
        <property type="entry name" value="Glyco_hydro_85"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cytosolic endo-beta-N-acetylglucosaminidase TIM barrel" evidence="2">
        <location>
            <begin position="65"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="340"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="351"/>
            <end position="362"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03644"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ82858.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="747" mass="85138" checksum="1602FB2384904129" modified="2016-11-30" version="1">MPSRQLQEDLLLPRSYALHSMDELRGWEPSDLDIPHIASIPLRVRKTNSTAKPRILLTHDMAGGYKEDASVQGNMFKDIYYIQRWHLVDMFNYFSHERVSIPPVNWINACHRNGIKCLGTFLVEGNSQMHQMEALLHGPPFINSSDDDPMRLWHPFYADKLVAIAKRYNFDGWLINIECEFFPFPTNPRFKAQELAKFIGYLTNKIHEEIPGSQIIWYDSMTDTGEIDYQNQLTHHNGLFFKNADGIFINYWWKKEYPEMTRRAAERYGKSGYDVYFGTDVWGRGTFGGGGFNSYRSVKTATLAQTSSALFGMAWTYENFDKADFDKMDRLFWTGGSYSEYPPMPPNDSELSPESEDSEDESVSQVHHKGIEDIVSLLPPAPGQDWFSTSFDKGFGLSFYHEGKKLLSQPWSHLSHQSILPNLKYHSPKMIPFDGNIKLTCSLENDYDAFIGGTSLLLKGQRLSHRESRDMETEISVPLYSLNVDTSQGCLIRYVYRNLLGDDAKVIMACHMLLQTVDSDASDELLDTWLLDTLLMDKDEGLRTTITVQSGDRLHSRCCIIPAMEEDQNKNGWIVKSAYIPAVSEGIKLTVSQVEMSVMANTANLVGIQPHLIMCLGHLSIVPLVEDEINQLKESQGQVGQLSWSQTKTKKIAENENEQIAHFFGTLHWRKQISLASRSQPWKQTDYYLIFYEAPDNTRMFLGTAFCPQYRISGLSCVNLQAEHRIIVEAVNVVGNIGAIAHITIPF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N210</accession>
    <name>A0A1C7N210_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Thiol-specific monooxygenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">fmo1_1</name>
        <name evidence="6" type="ORF">A0J61_08804</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the FMO family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000714">
        <property type="protein sequence ID" value="OBZ83150.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N210"/>
    <dbReference type="STRING" id="101091.A0A1C7N210"/>
    <dbReference type="InParanoid" id="A0A1C7N210"/>
    <dbReference type="OrthoDB" id="66881at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004499">
        <property type="term" value="F:N,N-dimethylaniline monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000960">
        <property type="entry name" value="Flavin_mOase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020946">
        <property type="entry name" value="Flavin_mOase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050346">
        <property type="entry name" value="FMO-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23023">
        <property type="entry name" value="DIMETHYLANILINE MONOOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00743">
        <property type="entry name" value="FMO-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000332">
        <property type="entry name" value="FMO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00419">
        <property type="entry name" value="ADXRDTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="6" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="4" id="KW-0521">NADP</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="283"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009183"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OBZ83150.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="283" mass="31732" checksum="F428DAC293B32728" modified="2016-11-30" version="1" fragment="single">MVLDSFVKKTIKRVAIVGCGPGGLAAARALKNEQCFDTITIFERNNHTGGTWKYSPEKNTPPPFPSVNALEVDNTLREPELHSPIYANLHTNLPHSVMCFHDVPFPEDTPLYPSHAHVMDYLSHVAEQENIVSLVRFRTLVENAEFIDEAWHISVLELETDRRYTEKFDALVVATGHYAVPYIPGLPGLKQISENKSIELVHSREYRQPNEYKNKVVFVIGGGSSANDIVREVATVAKKVYQSIRTPTELSRQSISLNPPNVQQVALVKQFSDGAIQLEDNQT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N2A5</accession>
    <name>A0A1C7N2A5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_08818</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000716">
        <property type="protein sequence ID" value="OBZ83131.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N2A5"/>
    <dbReference type="InParanoid" id="A0A1C7N2A5"/>
    <dbReference type="OrthoDB" id="2290289at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ83131.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="121" mass="13578" checksum="69F5050AEF720C80" modified="2016-11-30" version="1">MNNTAFRSLVQAVLSGIDTNRPLLGSSKLENCHQKDALPDVKAFIQDTQTEAQQGRSSPLKYTDPHGSRFLPLLPMYDCTPKQTQVHEQSFRKIIKSVDKEGIDTGKNLMMTLLKPAVIFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N2R1</accession>
    <name>A0A1C7N2R1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Translation machinery-associated protein 16</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">tma16</name>
        <name evidence="3" type="ORF">A0J61_08578</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the TMA16 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000674">
        <property type="protein sequence ID" value="OBZ83370.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N2R1"/>
    <dbReference type="STRING" id="101091.A0A1C7N2R1"/>
    <dbReference type="InParanoid" id="A0A1C7N2R1"/>
    <dbReference type="OrthoDB" id="270284at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1440.170">
        <property type="entry name" value="Translation machinery-associated protein 16-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021346">
        <property type="entry name" value="Tma16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038356">
        <property type="entry name" value="Tma16_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13349">
        <property type="entry name" value="TRANSLATION MACHINERY-ASSOCIATED PROTEIN 16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13349:SF2">
        <property type="entry name" value="TRANSLATION MACHINERY-ASSOCIATED PROTEIN 16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11176">
        <property type="entry name" value="Tma16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="165"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="176"/>
            <end position="191"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00034127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ83370.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="191" mass="22551" checksum="231316482BEC2521" modified="2016-11-30" version="1">MPTIKGNRKITLKTIKNRDGIHPYSRKAHQLSRVHQRKEKLAVQEKKKQNNPTGERWIWFRYAFDEDKTCATKAEMHELIEIYLSRHDEEIEALDNDRNKAHRRPKTPRQELLESIKQSELNEYISGMDLPDMTNGKVLRLLREWDGDKNSMKRITTIRLHKPAESATNTSMTVDTPKKETPKMKLDMMEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N2T6</accession>
    <name>A0A1C7N2T6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Putative oligoribonuclease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">rexo2-1</name>
        <name evidence="6" type="ORF">A0J61_10287</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the oligoribonuclease family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001104">
        <property type="protein sequence ID" value="OBZ81664.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N2T6"/>
    <dbReference type="FunCoup" id="A0A1C7N2T6">
        <property type="interactions" value="598"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N2T6"/>
    <dbReference type="InParanoid" id="A0A1C7N2T6"/>
    <dbReference type="OrthoDB" id="270189at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000175">
        <property type="term" value="F:3'-5'-RNA exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000467">
        <property type="term" value="P:exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034475">
        <property type="term" value="P:U4 snRNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034476">
        <property type="term" value="P:U5 snRNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd06135">
        <property type="entry name" value="Orn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.10:FF:000003">
        <property type="entry name" value="Oligoribonuclease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00045">
        <property type="entry name" value="Oligoribonuclease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022894">
        <property type="entry name" value="Oligoribonuclease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013520">
        <property type="entry name" value="Ribonucl_H"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003765">
        <property type="entry name" value="PRK05359.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11046">
        <property type="entry name" value="OLIGORIBONUCLEASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11046:SF0">
        <property type="entry name" value="OLIGORIBONUCLEASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00929">
        <property type="entry name" value="RNase_T"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00479">
        <property type="entry name" value="EXOIII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0540">Nuclease</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Exonuclease" evidence="5">
        <location>
            <begin position="16"/>
            <end position="189"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009921"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OBZ81664.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="191" mass="22025" checksum="D73D57816C074485" modified="2016-11-30" version="1">MNRLASSKILRMIKNPLVWIDCEMTGLDIEKDYLIEIAVLVTDSELNIVAKGPELIIHQPKEVMDNMNDWCIEHHGKSGLTKQVLESKVSIEEAEDKVYSFLKEHVPRGVAPLAGNSVHEDKRFLLKEMPKVVDHLHYRIVDVSTIKELTKRWYPEVASGVVKKAGHRALDDIVESIEELRYYRKHVFVKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N2W3</accession>
    <name>A0A1C7N2W3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">DIS3-like exonuclease 2</fullName>
            <ecNumber evidence="5">3.1.13.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">Dis3l2_1</name>
        <name evidence="8" type="ORF">A0J61_08489</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">3'-5'-exoribonuclease that specifically recognizes RNAs polyuridylated at their 3' end and mediates their degradation. Component of an exosome-independent RNA degradation pathway that mediates degradation of cytoplasmic mRNAs that have been deadenylated and subsequently uridylated at their 3'.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <cofactor evidence="5">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
            <location evidence="5">P-body</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the RNR ribonuclease family. DIS3L2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.13.-" evidence="5"/>
    <dbReference type="EMBL" id="LUGH01000659">
        <property type="protein sequence ID" value="OBZ83463.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N2W3"/>
    <dbReference type="FunCoup" id="A0A1C7N2W3">
        <property type="interactions" value="534"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N2W3"/>
    <dbReference type="InParanoid" id="A0A1C7N2W3"/>
    <dbReference type="OrthoDB" id="372421at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000932">
        <property type="term" value="C:P-body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000175">
        <property type="term" value="F:3'-5'-RNA exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000956">
        <property type="term" value="P:nuclear-transcribed mRNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990074">
        <property type="term" value="P:polyuridylation-dependent mRNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.690">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.700">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03045">
        <property type="entry name" value="DIS3L2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041505">
        <property type="entry name" value="Dis3_CSD2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028591">
        <property type="entry name" value="DIS3L2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041093">
        <property type="entry name" value="Dis3l2-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001900">
        <property type="entry name" value="RNase_II/R"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022966">
        <property type="entry name" value="RNase_II/R_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050180">
        <property type="entry name" value="RNR_Ribonuclease"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23355:SF9">
        <property type="entry name" value="DIS3-LIKE EXONUCLEASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23355">
        <property type="entry name" value="RIBONUCLEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17877">
        <property type="entry name" value="Dis3l2_C_term"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17849">
        <property type="entry name" value="OB_Dis3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00773">
        <property type="entry name" value="RNB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00955">
        <property type="entry name" value="RNB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01175">
        <property type="entry name" value="RIBONUCLEASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 8" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 5" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5" id="KW-0464">Manganese</keyword>
    <keyword evidence="2 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0540">Nuclease</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RNB" evidence="7">
        <location>
            <begin position="374"/>
            <end position="713"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="190"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="828"/>
            <end position="850"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="12"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="28"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="190"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="207"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="828"/>
            <end position="839"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="841"/>
            <end position="850"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="386"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="395"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="site" description="Important for catalytic activity" evidence="5">
        <location>
            <position position="394"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03045"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00955"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OBZ83463.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="924" mass="106486" checksum="9178203B78C1458A" modified="2016-11-30" version="1">MHRTNRYRRRKAADESDNWRRKEPEEYNLNQSRWLPNDNTSQWNNHWDQQPLTDTTPYPAKTEQESPWQAYSLQHQSPPVKEPVLAWTAYSENNRTPVEDTSYRPPVRKSIYRPYLRLDEIERRMTEGGDVFEGCLRLSRNKDDAYVTCNRLDSDIYIGGIFDRNRAMDGDFVAVELLDIDDIWRQRQEREQKKETRRKEQERTDDQPGEDPDASVTLEEEVELEDEQKPKYGGRVVGLLEKSPNTAYHGTIVKTRHADVKLEGPLKLAWFKPTDRRLPFFALKGNDIPEDLQENEEYYKTHLFSAKIRSWAATSHNPLGTILGNLGPISDFSTQKNAILTDYSIEMDAFSHQALDCLPKQLPWQIPSAEYQKRRDLRLKRIFTIDPRTAKDLDDAVHITELEDGFFEVGVHIADVTHFLKMGTALDNEAKARGTSTYFVDGVIPMLPPLLSEELCSLNPGVDRLAFSVIWKMDMTGRPVDTWYGKTIIRTCAKLAYQDAQVVIEGGELPSDVILFDGHDGAGIAYDIQLLQRLSVHMRKRRYENGSLSLNSVKLQFELDQFGAPVEVTAFEAKEANRLIEEFMLQANISVASKILSTFPEEALLRRHQDPTERRLNQFLRITEVLGLDFDGSTAGSLQDSFDRISNPHVRNVLLVLAIRTMQRAKYICSGKISIAKYRHYALNEPIYTHFTSPIRRYADVVVHRLLNAALSCKEEEVQCPYDRKIVQKISFLCNAKKDGAKNAQDTDSTVYLAKYLWQRERSTGPIYKKADVIVVSKDTFEVYIAEYGIERRIYLKGLPVQKYHFDKHTLALDIYWKRGEPVTMHNEEKIYAQERTPSDDFSDSDDEEEDRAIEDSLAGLLLQDTPAYDPDHTVNADDLIPPVILDSESCLQQLKMFSTIDVRLQVNMDRIPPIINIYPVNPF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N2Y2</accession>
    <name>A0A1C7N2Y2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">histidine kinase</fullName>
            <ecNumber evidence="2">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="primary">NIK1_1</name>
        <name evidence="15" type="ORF">A0J61_08559</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="2"/>
    <dbReference type="EMBL" id="LUGH01000671">
        <property type="protein sequence ID" value="OBZ83387.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N2Y2"/>
    <dbReference type="SMR" id="A0A1C7N2Y2"/>
    <dbReference type="STRING" id="101091.A0A1C7N2Y2"/>
    <dbReference type="InParanoid" id="A0A1C7N2Y2"/>
    <dbReference type="OrthoDB" id="10266508at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071474">
        <property type="term" value="P:cellular hyperosmotic response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06225">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="CDD" id="cd16922">
        <property type="entry name" value="HATPase_EvgS-ArcB-TorS-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd17546">
        <property type="entry name" value="REC_hyHK_CKI1_RcsC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.2300:FF:000235">
        <property type="entry name" value="Probable nik-1 protein (Os-1p protein)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.565.10:FF:000010">
        <property type="entry name" value="Sensor histidine kinase RcsC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.130:FF:000002">
        <property type="entry name" value="Two-component osmosensing histidine kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.120.1530:FF:000002">
        <property type="entry name" value="Two-component osmosensing histidine kinase"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1530">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="entry name" value="Histidine kinase-like ATPase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003660">
        <property type="entry name" value="HAMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45339">
        <property type="entry name" value="HYBRID SIGNAL TRANSDUCTION HISTIDINE KINASE J"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45339:SF1">
        <property type="entry name" value="HYBRID SIGNAL TRANSDUCTION HISTIDINE KINASE J"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00672">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18947">
        <property type="entry name" value="HAMP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00304">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="CheY-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF158472">
        <property type="entry name" value="HAMP domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="Homodimeric domain of signal transducing histidine kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF58104">
        <property type="entry name" value="Methyl-accepting chemotaxis protein (MCP) signaling domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50885">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="11" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7 15" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3 10" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="9" id="KW-0902">Two-component regulatory system</keyword>
    <feature type="domain" description="HAMP" evidence="14">
        <location>
            <begin position="70"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="domain" description="HAMP" evidence="14">
        <location>
            <begin position="162"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="domain" description="HAMP" evidence="14">
        <location>
            <begin position="254"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="domain" description="HAMP" evidence="14">
        <location>
            <begin position="346"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="12">
        <location>
            <begin position="420"/>
            <end position="641"/>
        </location>
    </feature>
    <feature type="domain" description="Response regulatory" evidence="13">
        <location>
            <begin position="796"/>
            <end position="916"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="11">
        <location>
            <begin position="379"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="10">
        <location>
            <position position="845"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="15">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="OBZ83387.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="931" mass="101821" checksum="7D8E0C4EE974A491" modified="2016-11-30" version="1" fragment="single">KKIEVESGGEILELKNIVNNMVDQLNVFASEVSRVAREVGTEGKLGGQAVVPNVDGTWMDLTDNVNQMAANLTSQVRSIAEVTKAVALGDLSKKIEVESGGEILELKNIVNDMVDQLRVFASEVTRVAKEVGTEGKLGGQAVVKGVAGTWNELTDNVNQMAANLTTQVRSIAEVTKAVASGDMSKKIHVETSGEILELKITVNSMVDQLRVFASEVTRVAREVGTEGKLGGQATIIGVDGTWKDLTDNVNLMASNLTDQLRSIAAVCKAVAQGDLSKKIEVEVHGEIAELKNTINTMVDQLSSFASEVTRVAKEVGTEGKLGVQAQVEDIQGLWRDITSNVNTMASNLTTQVRAFAQISAAATENDFSRLITVEASGEMDSLKTKINQMVNSLRDAIQKNRQAREAAELANRSKSEFLANMSHEIRTPMNGIIGMTSLTLETELTRQQRENLMIVSSLANSLLSIIDDILDISKIEAGRMTIESIPFSLRSAVFSVLKTLAVKANQKKLDLIYNVDSAIPDHLIGDPLRLRQVITNLIGNAVKFTTRGEVSLETRVVSDSDDNVILELCVKDTGIGIQEDKLSLIFDTFCQADGSTTREYGGTGLGLSISKHLVQLMGGDLWVKSVYGRGSQFYFTLNFKRYPKERHDAFEKMKRYKGRNILFLDGNNDEMGIEPKLCELGLTPFRVTGISDSANMSSLPIFQSTNNKQPPLFDTVIVDNVAYAEKIREAVHLRYTPIILIAPEVHSLNMKLCIDLGITGHINSTVTLSDLAYTLLPALESHSSLPSDSSIPLPLDILLAEDNIVNQKLAVRILEKFGHKVEIVSNGKLAVEAFENSNYDLILMDVQMPVMGGFEATQKIREIEHRIGNGSRVPIIALTAHAMIGDREKCLQSGMDEYVTKPLRFPELIAAIKKFAPQSAHTMLVRSNKKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N302</accession>
    <name>A0A1C7N302_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_08507</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000662">
        <property type="protein sequence ID" value="OBZ83441.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N302"/>
    <dbReference type="InParanoid" id="A0A1C7N302"/>
    <dbReference type="OrthoDB" id="2263516at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ83441.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="110" mass="12657" checksum="2F8E648614BEF301" modified="2016-11-30" version="1">MNPKDIVLPPPLPMHKETTLLYSPINRTSFESDSTFMSDDSDLNEHDFWQAHSSTMIISPTQNKPISLAAQVKRILGTVIQETDQAIEQEWDQSRQRLDQTLIHLPHIHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N3B5</accession>
    <name>A0A1C7N3B5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Mediator of RNA polymerase II transcription subunit 23</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">med23</name>
        <name evidence="6" type="ORF">A0J61_08457</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the Mediator complex subunit 23 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000653">
        <property type="protein sequence ID" value="OBZ83488.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N3B5"/>
    <dbReference type="InParanoid" id="A0A1C7N3B5"/>
    <dbReference type="OrthoDB" id="9982951at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016592">
        <property type="term" value="C:mediator complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005667">
        <property type="term" value="C:transcription regulator complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010628">
        <property type="term" value="P:positive regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021629">
        <property type="entry name" value="Mediator_Med23"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12691">
        <property type="entry name" value="MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12691:SF10">
        <property type="entry name" value="MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OBZ83488.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="1672" mass="193084" checksum="4A8A9F5E167DAAA6" modified="2016-11-30" version="1">MEPLRAVISRLFVDIQDNQPIPDWLSLEKESTQTFDGLFDKSPSRKRRRYLLHPETKDEHNYKNTIVNHIHTTHRIDCEALALDFVRASQVGGGNITDQLKVIMLKYREPPLTLEKASRLITFLHHVLKLVPVTPALNTPQKPFPLGLLLEDITLTLSTLQPAIWIITIQFMLSCLRSTPQLHTAITTPVVLSIIKHVLLELTRLPSTNMNYMQEKSFLVGKELLDLFLIRNGHNEHDVNITVVAGSSQSKSTGIAISYYDVVYSFPKLYGHFLNAQSMPEAAAAPQPSIANQNIWLMTITYLAQSILQDHRLIDRVPSLMAINIIKHILREINTLPADLTTAQVNCLNKGKELINLLLLGPLGDGAGAVSHYDVIVALPDVYGHFQHGTFAQSVHWVMEKFINELGKRRRHLAFLMMPPDASWPLISQMSRRHEYNDLTTRTSYHMFEGDLIEFVKEGSSTNIQTHFRDMLFQRASMDEFRELAMSLTQTGLDTTLIRKAMVSKVRDVIRCIQHYSQTGKRDGQNAEMVDKLQESFNPATTSIRSEDIKMMIPSNIDLWELMIETADQLYSFVSAEFFTYEDLLHDFYDLVYTSYDEPYHPTVKDRITKDNGLVWLLLQLFYIEKVSKEVIQKDFEQDEKLFGKLVRLYNQEQTDSKDAFTLRDLALQCAVNHQKANIRDVANIKHRHPLIATSLQHAGLCYQIQAYFSSYYHSNVPTNSTLFSQLDLQEMVKIAMESQLRQDVVPYTLYVYLVPTKADIDTLGYPSATYIKGGMLNYRLLDLLCVNAKHRLLQVIYKMMLDSETGPRYQSNTGAPSVACVPPNVVDVVYKLLYSAPCSAELMVKEILDKLRRCDKTIKTKHTGEATQQPQLPDQTMRWLQSILQLMNYRFIRFLKYSSFSSGLLHYIRYSISYLENRQCYQTLESFAINVIHMQTDAKLLRSLDDPHREKPIWFAESEMLSRLTVCTISRLIKTRGQADIRTDQIHRVLSSLYEYRIEWSPQAMSFFPPAVQSFYNTVNASLPARPVVTPQKVQYLMSNNKAFTAYILQGSPEAEQMTVQFFSALENQPLLLCSIWVIALTRNTTECFNMPAVRKLLMLISPSRMATNTIDLVDFILSVEYPPNSSEFLFALLDTFIWKNQWINFNHVLFAFMKGSGSSDRTTKAIRYVRYLLLESTEFQNRVKLWDSLDFSRRYWTEEDFHDKLMRYLYEYPEYHEFEAYGMHQFKPTMDIPQTQTKLPIYYSSIISDFVSWMESLVMRLIEYDQLDLLVNMLDKYSHLFYLHQSPLAFVVNILLYYHTSPTLRNPLLLKRILRLLDFEQYTIAHEIQNYAFSDQDDGSAFNSTYFENVIHKLAGNIDPRKCAPRTNPNLPERHFREIGSPAVEGILIAALEIMATPIAPSVVIRQLLNLALLRKSHHVGVSALTLHAIGLLIPMLPQNEYVHPIFLELNELIASDPYLLEVSEPCRLIRCGIPRKVNGRFIMTQSLPDMTATTTLKDTLGVRLRKAMMFPYIFNDYTFNLHNYSTNAPNSFLCLFHSIIHYSSLDIFSIFLEYTQKLRSSGQVKTDVQLLYMCFLIGPALHRIEKLDCGDADFLIELMYMVKQVTTFMELRDGWTTQALEQVYDFLYHIRTRFVKSNELASQLKDIIKSMNPPISQRLLRLVSEKKTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N3G7</accession>
    <name>A0A1C7N3G7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_08287</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000624">
        <property type="protein sequence ID" value="OBZ83662.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N3G7"/>
    <dbReference type="STRING" id="101091.A0A1C7N3G7"/>
    <dbReference type="InParanoid" id="A0A1C7N3G7"/>
    <dbReference type="OrthoDB" id="5570013at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="109"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ83662.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="487" mass="54136" checksum="EB8249538BF223BA" modified="2016-11-30" version="1">MSSSNNPKSFYNQSEYGTAKDGHQMIGHSGDTSSDLTPPPPYTNGQSSGDIYPRESDGRLQQGEQTGLLGNQNVLSSLKSNIPNWRGLPYSFLGENRIQLEEPRRPRRYCRWICLIIPICILAILSIALYLKPRRGSRFACGGSTESLNSIPFFIEFKDNVEVIVMGHVSGGRILVSPGNQRHEGAIWTDIQYTPSRLQPQFSHRIEQLDNGDLTRLVLNMPQRQEPDDCIQVSLLIDLPYGAKIARFITSNMDIEVEQPIKKELETFELTTSNGDIFLNHWVGESLLAKTTNGNIHVQGSLSADKSIHLETTQGKVTFFHAAIAKSTLEVYNTNGPIRVLEALRSDGSVQLKTTNGMIEANTIAADTILLVNSNGKVNTNHIRAEKSIVVETTNAPIQLAVTGVKNNHLSLRTTNAPVRLHVTHEFEGDFSLETSHSEKVIVKDDPDITFQSDFRYFKQGYRKGLGNKGDLSVKTTNDLIEVSFDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N3Q1</accession>
    <name>A0A1C7N3Q1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">A0J61_08280</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000623">
        <property type="protein sequence ID" value="OBZ83667.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N3Q1"/>
    <dbReference type="FunCoup" id="A0A1C7N3Q1">
        <property type="interactions" value="14"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N3Q1"/>
    <dbReference type="InParanoid" id="A0A1C7N3Q1"/>
    <dbReference type="OrthoDB" id="39175at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050987">
        <property type="entry name" value="AtrR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46910:SF3">
        <property type="entry name" value="HALOTOLERANCE PROTEIN 9-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46910">
        <property type="entry name" value="TRANSCRIPTION FACTOR PDR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="6">
        <location>
            <begin position="40"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="119"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="134"/>
            <end position="146"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OBZ83667.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="694" mass="79194" checksum="41A208A804EF0B54" modified="2016-11-30" version="1">MYHPNTSPNSQPPLPRLPVVPIRKQQPEKSERKRTKKSRACDLCRRKKIRCDYDQDYPQHSCSSCKSYGKDCTFNEAAKKRGPPKGYVEGLESRLRRMEKLLLTVAENGNLPPEVLRATSELAESSSEKEESPNSDLTEEAQSPNKKPSVAQKMEDGSEEGATRIPTCDSSEPFSYVGSSSGIYLLSRLFTRDTAHMDRKEKEALPRPLDDNEEDLMVARFGGDPLNKLGFGRILNPDWKMPPKDLTDHLIQMYFKRINTMLPILDEDSFYQEYRKANHASTFIPIIMAICRGSCRLLEEDDFLVQKYKIDRAHFFRDIQKQMDTYFEVDFLQPKIETIQVLLIQASNTEKWGIESSDWITTSIAVKMAQDLGLHRANTQHQGVPKKDMEAKKRLWWSAYIIDRWVCASLGRPLTISDADCDIDHPDPNDQKYALFFYMVKLSCILGDVLRALCSPRARLMSEKGIGLENISRSLEQMLLEWKRLLPPHLSLSEFELHRISRKDLDIEFKAKLSNGGLCVVTPRIASQLQMAYIAVYLLIKRPFISMGIGNGSTVKMPVECQNAIKIAVDLFDVMRITDLLCNWSLGSYWLSQTQMLLLLNFRNVDTGLSAESKRFSERFKTRHHPSIVPFLELVSSVISGEGNHDTNSNDSHSSTSNKNIVTSVDQQQSLWEASNGIEWQEMVKLLAETGYQI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N3W3</accession>
    <name>A0A1C7N3W3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">GATA zinc finger domain-containing protein 8</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">gtaH</name>
        <name evidence="7" type="ORF">A0J61_08187</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000608">
        <property type="protein sequence ID" value="OBZ83760.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N3W3"/>
    <dbReference type="STRING" id="101091.A0A1C7N3W3"/>
    <dbReference type="InParanoid" id="A0A1C7N3W3"/>
    <dbReference type="OrthoDB" id="2162994at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00202">
        <property type="entry name" value="ZnF_GATA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.50.10">
        <property type="entry name" value="Erythroid Transcription Factor GATA-1, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051140">
        <property type="entry name" value="GATA_TF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000679">
        <property type="entry name" value="Znf_GATA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013088">
        <property type="entry name" value="Znf_NHR/GATA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45658">
        <property type="entry name" value="GATA TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45658:SF122">
        <property type="entry name" value="GATA ZINC FINGER DOMAIN-CONTAINING PROTEIN 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00320">
        <property type="entry name" value="GATA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00401">
        <property type="entry name" value="ZnF_GATA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57716">
        <property type="entry name" value="Glucocorticoid receptor-like (DNA-binding domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00344">
        <property type="entry name" value="GATA_ZN_FINGER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50114">
        <property type="entry name" value="GATA_ZN_FINGER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="GATA-type" evidence="6">
        <location>
            <begin position="192"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="120"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="328"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="136"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="328"/>
            <end position="345"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00094"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50114"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OBZ83760.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="357" mass="40433" checksum="D8DAAD61E0C0C657" modified="2016-11-30" version="1">MDVAQLCTDPLEPSPSLISTNHEENSSQRSSANVNKIDFLLSGYQESDSTTTTTTTTATEIPNSIKKVLIQCSQLCEDIWQLKLHNKSMSDQERDETINHLSEAAQIALKAIQSSEYYTADNQKRRNSNANMSLSQDEDEEEEEEEDEEDDFRSIHTSTINDYAEYQLIRQARNIQSNSRARPRYRRRNRRSMIGQKCHSCNTTETPEWRRGPDGARTLCNACGLHYSKLLKKGSIGVQTQNYLITGGVPKVSSSSKQTAANTLKNYRPTEGNTINYPFVLMDPRRNANNEELKQEAPTSRSYQTSVHPQHLAPATIEDFVNINQNNASYSNRNSRKSNSNGSASIGPLRIHQWKHQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N417</accession>
    <name>A0A1C7N417_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">GTPase-activating protein GYP5</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">GYP5_2</name>
        <name evidence="4" type="ORF">A0J61_08104</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000595">
        <property type="protein sequence ID" value="OBZ83843.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N417"/>
    <dbReference type="InParanoid" id="A0A1C7N417"/>
    <dbReference type="OrthoDB" id="295078at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031267">
        <property type="term" value="F:small GTPase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.270">
        <property type="entry name" value="putative rabgap domain of human tbc1 domain family member 14 like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.80">
        <property type="entry name" value="Ypt/Rab-GAP domain of gyp1p, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000195">
        <property type="entry name" value="Rab-GAP-TBC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035969">
        <property type="entry name" value="Rab-GAP_TBC_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050302">
        <property type="entry name" value="Rab_GAP_TBC_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47219:SF9">
        <property type="entry name" value="GTPASE ACTIVATING PROTEIN AND CENTROSOME-ASSOCIATED, ISOFORM B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47219">
        <property type="entry name" value="RAB GTPASE-ACTIVATING PROTEIN 1-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23436">
        <property type="entry name" value="RabGap-TBC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00164">
        <property type="entry name" value="TBC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47923">
        <property type="entry name" value="Ypt/Rab-GAP domain of gyp1p"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50086">
        <property type="entry name" value="TBC_RABGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rab-GAP TBC" evidence="3">
        <location>
            <begin position="160"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="536"/>
            <end position="556"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="586"/>
            <end position="605"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="852"/>
            <end position="871"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="440"/>
            <end position="509"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="705"/>
            <end position="735"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="543"/>
            <end position="556"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OBZ83843.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="929" mass="105324" checksum="E5DBCA9BA6D8106F" modified="2016-11-30" version="1">MAATVLENSLLLAPQEQQRLEDFSPNQPHILQHDLILRPSKSEDINKRPQCVCPEKSVSSTHVERKKDSQIPAPLCLESNNTVKEEKEMKREENAISQTCLIKVLEKQKSDSKSISMDTIVTPLLDNSTATEPFWENFIRNANSIEARAELLEKLAHGHDIPEDIRGIVWQAICQTSSASRAAILYEQLITEPSPYDAVIEKDTQEMDRQESLMRILKAYSLYDTRVGYLPGMAQLVSPLLIYMPENEAFGMLTRLMETYDMRSLYMLNMEGLHLRLDQFKMILAQTLPKLDEHLTRLSIYPSIYASQWYLTLLASCISSQQHIARIVDIALLEGVAETVIRVSILLLQKNEARILSLNQYDDVLNYLTSTELHSASYANGDIGGRALVRDIIQMNPMIVKMHHIAXTQAKDLEREKSRTHAAMTTWRMKKEKIASVQTIPKLQQQIEDLVTAMSQLQKEHAAMAQNNMSLRMREVDQEAAQSKLAKRNAVLEKRIKKYKVKLANATTHSESDDIAPAKLTSASAIPNTTAILAPLPASMAPENKETNPENTNERRQDQYDSFVASLRGSGDFGALIAGALAPKLAEEKKEHESEEKKDMSETEKRLLEEQENRKKIDMTLQNVTSELVAIKLDHFETKQRYETLYHHCEQLTAQIQHMQESQNALVQKIIYLESELDDTQAERDQILQDQEEVLEVAMVAKKTAAELQFEKLSMAKEMERLEQAIKDLEEEKKAFFMPRSSFTEEVFAAHSILFGPSKLTTQKEANRRHTMQLGSHKSTTDDEYKTKFVESELRCRELEKYLAETKVRLAEFESGTGTIGSPRGSMQLPRRASIYNNKRSSAASLSMLANRMSTPTSPRERRGSTESYASSVTSLTSVNSSNYNSKRSSVYSRIWNAFGAPTTPINATAPTNMKSEILCQEPEIIEQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N4J2</accession>
    <name>A0A1C7N4J2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="9">ABC transporter G family member 21</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">abcG21_1</name>
        <name evidence="9" type="ORF">A0J61_08002</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000579">
        <property type="protein sequence ID" value="OBZ83948.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N4J2"/>
    <dbReference type="FunCoup" id="A0A1C7N4J2">
        <property type="interactions" value="139"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N4J2"/>
    <dbReference type="InParanoid" id="A0A1C7N4J2"/>
    <dbReference type="OrthoDB" id="245989at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03233">
        <property type="entry name" value="ABCG_PDR_domain1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013525">
        <property type="entry name" value="ABC2_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029481">
        <property type="entry name" value="ABC_trans_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034001">
        <property type="entry name" value="ABCG_PDR_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010929">
        <property type="entry name" value="PDR_CDR_ABC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19241">
        <property type="entry name" value="ATP-BINDING CASSETTE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01061">
        <property type="entry name" value="ABC2_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14510">
        <property type="entry name" value="ABC_trans_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06422">
        <property type="entry name" value="PDR_CDR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="525"/>
            <end position="545"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="557"/>
            <end position="578"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="598"/>
            <end position="622"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="634"/>
            <end position="656"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="662"/>
            <end position="680"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="692"/>
            <end position="710"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="771"/>
            <end position="795"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="8">
        <location>
            <begin position="158"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="87"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="47"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="98"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="882"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OBZ83948.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="882" mass="100089" checksum="51BE141D74CE399F" modified="2016-11-30" version="1" fragment="single">MDNPSLQNMQQQRTNRDEEFGHKHHHSSDESTIEGVHGKEEIALNDTEVTFETQQNSTTGGYGEADGNAVNIEDAMSNYEEIRRELTHQSRLSRHKSVSPDDAEKGDSNDFDLTDFLRDQSDKGQAAGFFPKHMGVVWKNLTVQGLGADAKTIPTNWTWIRDFGKFWKWGKHSGHDFTILRDNDGFVKDGEMLLVLGRPGAGCTTLLRILSNMRASYTKVEGEVHYGGIEATEFGKHFRGEVCYNEEEDLHYPTLTTKQTLSFALKNKTPGKRLPDETKKEFINKILYMLGNMLGLTKQMDTMVGNAFVRGLSGGERKRLSIAEQMTTRSSINCWDCSTRGLDASSALDYVRSLRIMTDIMHKTTISTLYQASDSIFHLFDKVMVLDEGRCIYFGPTSGAKSYFEDMGFYCPDRKSTPDFLTGLCNMNEREYREGYKNKVPINAVQFEKAYKESTIYAEMMRERTEYEQKIAQDRPDEKFRQAFVEAHQKHASKRSPFVATYYQQVKSLTVRQFQLILGDKGALVSRYGGVVVKGLIMASCFFMMPNDASGAFSRGGSFLFSLLFNALIAQSELAAFMQGRRVLEKHKHYALYHPSAFYIATVVADIPLAIVQVIIFEICVYFMMGLVMEAGRFFTFAIILIVTNLCMNGFFRFWGAVSPNFFTASQLSSILLIACLIYCGYQIPYKHMHPWLFWIYWINPLAYGYKALISNEMRNFHFSCEGIYSVPYGPSYTDDQYKTCLLEGAKPGVNYVLGDDYMAEGYGYYVWQRWINFVAVILFFLFFTVLTALAMEYVELQKEGSITKVYKAGKAPKELDESQALQQTVTEVEEKMEAVTDGTTFSWHHMNYTVPVKGGTRQLLNDIGGIVRPGHLTALMGSSGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N4S6</accession>
    <name>A0A1C7N4S6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein YbeQ</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">ybeQ_0</name>
        <name evidence="1" type="ORF">A0J61_07837</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000554">
        <property type="protein sequence ID" value="OBZ84113.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N4S6"/>
    <dbReference type="STRING" id="101091.A0A1C7N4S6"/>
    <dbReference type="InParanoid" id="A0A1C7N4S6"/>
    <dbReference type="OrthoDB" id="272077at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052945">
        <property type="entry name" value="Mitotic_Regulator"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006597">
        <property type="entry name" value="Sel1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43628">
        <property type="entry name" value="ACTIVATOR OF C KINASE PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43628:SF1">
        <property type="entry name" value="CHITIN SYNTHASE REGULATORY FACTOR 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08238">
        <property type="entry name" value="Sel1"/>
        <property type="match status" value="15"/>
    </dbReference>
    <dbReference type="SMART" id="SM00671">
        <property type="entry name" value="SEL1"/>
        <property type="match status" value="14"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81901">
        <property type="entry name" value="HCP-like"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ84113.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="687" mass="76893" checksum="3B6F7A66050A9B24" modified="2016-11-30" version="1">MTASLTHLVYASKRMFKNNRLSFLSLPASLSSKTNNKSFISIYRRSRRSSVSTCHTEASSHVLSEYTPDDLFELAQDHLFGRDNKPKDETLAILCLKDAAINFHHSGAQAILGFCYEFGMGTTINFQLAEHYYMMSIKTALQQEHTNQFECFTEPTLVSVIRLSFLRKYGRPGVRINRVEAEYWENKINQRGEQAIQWIRRAAEEYYCSSSQYCLGVCYHDGIAVPKDETVAFAWYKLSAEQGNSRGQGILGFCYGEGFGVAKSEQTALTWYRLAAAQGETVAIYNIGYCYEDGIGVDKDHEEAVRWYILAAEQGNAFAQNSLGYCYEDGIGVSRDKVAAASWYRRSAEQGYPWAECNLGYCFQNGIGVEKNVALGAYWYGQAARQGHARAQHNLGFCYQNGIGVTKNLKLAVAWYTKSAQQGNIFAFHSLGYCYQNGLGVEKNQRESVYWYLKSAEHNHAPAQLSLGFCFRNGMGVAKDEVEAVKWFRRSALQGNPLAQNSLGFCYEEGLGVAKDMKTAVYWYIKAAKQDNPWAQCNLAFLYANGNGVVKNSVKAVYWYRKAAAQNHARALDKLGLHLQSGVGVEQDLKLAFQLFLRAAKQDHISAQYHLGDCYEAGLGVPVDLQQAAIWFERAAMAGCRNSYERLRRLLARVCLNSQSMVTPGSSKTEDDLIYSGFICGHAAPAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N539</accession>
    <name>A0A1C7N539_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Endonuclease/exonuclease/phosphatase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_09495</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000863">
        <property type="protein sequence ID" value="OBZ82454.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N539"/>
    <dbReference type="InParanoid" id="A0A1C7N539"/>
    <dbReference type="OrthoDB" id="2290280at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="31"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ82454.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="295" mass="34003" checksum="52CAB2FAA07E09E0" modified="2016-11-30" version="1">MTHYLTSPIMHILNIYAFATRQDHLAYFRALAANLPLMSILHSFIITVIVVGNFDYDTHKYNTIDLSWSDLLLGVFHDCFEQLRLPTLIDTTGRRSLPDYIFYSSYFPGDLVSMSHSFVSYEWTDHALLTTAFRLSCESMGKGLWKANLFLAKLAPFREGLTSHIQDYIMSENLLNPLSTNSAHKIRDALKVQAKIYTRSFQMDRLNWQRKSLKLPQAKFNRILREYKHTSILSKILPSIEVLIGKLQSEVAYIDQMKSGKHWREQGKNLAGFLKKTASTRIAQHMNLALQDPPN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N638</accession>
    <name>A0A1C7N638_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 8">Protein N-terminal glutamine amidohydrolase</fullName>
            <ecNumber evidence="3 8">3.5.1.122</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6 8">Protein NH2-terminal glutamine deamidase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="primary">tun</name>
        <name evidence="10" type="ORF">A0J61_07368</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Mediates the side-chain deamidation of N-terminal glutamine residues to glutamate, an important step in N-end rule pathway of protein degradation. Conversion of the resulting N-terminal glutamine to glutamate renders the protein susceptible to arginylation, polyubiquitination and degradation as specified by the N-end rule. Does not act on substrates with internal or C-terminal glutamine and does not act on non-glutamine residues in any position.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7 8">
            <text>N-terminal L-glutaminyl-[protein] + H2O = N-terminal L-glutamyl-[protein] + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:50680"/>
            <dbReference type="Rhea" id="RHEA-COMP:12668"/>
            <dbReference type="Rhea" id="RHEA-COMP:12777"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:64721"/>
            <dbReference type="ChEBI" id="CHEBI:64722"/>
            <dbReference type="EC" id="3.5.1.122"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="2 8">Monomer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 8">Belongs to the NTAQ1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.5.1.122" evidence="3 8"/>
    <dbReference type="EMBL" id="LUGH01000493">
        <property type="protein sequence ID" value="OBZ84583.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N638"/>
    <dbReference type="STRING" id="101091.A0A1C7N638"/>
    <dbReference type="InParanoid" id="A0A1C7N638"/>
    <dbReference type="OrthoDB" id="191192at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008418">
        <property type="term" value="F:protein-N-terminal asparagine amidohydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070773">
        <property type="term" value="F:protein-N-terminal glutamine amidohydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.620.10">
        <property type="entry name" value="Protein N-terminal glutamine amidohydrolase, alpha beta roll"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037132">
        <property type="entry name" value="N_Gln_amidohydro_ab_roll_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039733">
        <property type="entry name" value="NTAQ1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023128">
        <property type="entry name" value="Prot_N_Gln_amidohydro_ab_roll"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13035">
        <property type="entry name" value="PROTEIN N-TERMINAL GLUTAMINE AMIDOHYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13035:SF0">
        <property type="entry name" value="PROTEIN N-TERMINAL GLUTAMINE AMIDOHYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09764">
        <property type="entry name" value="Nt_Gln_amidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Protein N-terminal glutamine amidohydrolase alpha beta roll" evidence="9">
        <location>
            <begin position="21"/>
            <end position="194"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012718"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00021247"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00029677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00048768"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU367082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF09764"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OBZ84583.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="201" mass="23830" checksum="D9BE3F5D8BC95393" modified="2016-11-30" version="1">MTLTEDQGLDVLKFKQAELNYTANYCEENIYKLCEEIQTKRPDLLEYFHVVFISNKNRMVPLWQQRAGREEDHMVVWDYHVVLYFEKEGEKALVYDFDTLLPFPTPADVYATNTFKPHLVFNDRYHHAFRLIPAKVYLESFQSDRSHMLKEDGCYIAQPPSYPIISKGQHNLDEFISMESCLYGNVLSNNQFYDRLFNTLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N658</accession>
    <name>A0A1C7N658_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Zinc finger PHD-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">A0J61_07337</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000489">
        <property type="protein sequence ID" value="OBZ84612.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N658"/>
    <dbReference type="STRING" id="101091.A0A1C7N658"/>
    <dbReference type="InParanoid" id="A0A1C7N658"/>
    <dbReference type="OrthoDB" id="5876363at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001965">
        <property type="entry name" value="Znf_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="SMART" id="SM00249">
        <property type="entry name" value="PHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Zinc finger PHD-type" evidence="4">
        <location>
            <begin position="3"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OBZ84612.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="205" mass="24153" checksum="2C5DD4E17131F04F" modified="2016-11-30" version="1">MLICYRCREQLREHGKKPYITCKYCTVSWHIDCLIQPSHTPIPDTLDWRCPQHQERAHTTKQRVKGKDGRTVKVQHTSEDITFHEAENIVKYGGVVYGIPTWHIENEFLDFAAKRRRAMTLDRDYKDSTEEWINSLPVDFPVYKTKEQQQGVEMLLEAAHHVNTNKRQIELDEDEYKRMEAIDQLIKLKGGEDELLKILSSKTNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N6C1</accession>
    <name>A0A1C7N6C1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_07785</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000546">
        <property type="protein sequence ID" value="OBZ84166.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N6C1"/>
    <dbReference type="InParanoid" id="A0A1C7N6C1"/>
    <dbReference type="OrthoDB" id="2279408at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ84166.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="87" mass="9573" checksum="E9C8079F4C0D25B1" modified="2016-11-30" version="1">MRVLGIGYIGLAITWDPPAKEIKESPFKDAPQPNEDPFGTVAEQQDFLQAICKHLQANEAVPAGTFCTHPDAMIYLNIPDTVDGYKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N6F4</accession>
    <name>A0A1C7N6F4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Alpha-mannosidase</fullName>
            <ecNumber evidence="3">3.2.1.24</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">ams1_1</name>
        <name evidence="10" type="ORF">A0J61_07242</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Degrades free oligosaccharides in the vacuole.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Hydrolysis of terminal, non-reducing alpha-D-mannose residues in alpha-D-mannosides.</text>
            <dbReference type="EC" id="3.2.1.24"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the glycosyl hydrolase 38 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.24" evidence="3"/>
    <dbReference type="EMBL" id="LUGH01000479">
        <property type="protein sequence ID" value="OBZ84712.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="FunCoup" id="A0A1C7N6F4">
        <property type="interactions" value="73"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N6F4"/>
    <dbReference type="InParanoid" id="A0A1C7N6F4"/>
    <dbReference type="OrthoDB" id="10261055at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000329">
        <property type="term" value="C:fungal-type vacuole membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004559">
        <property type="term" value="F:alpha-mannosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006013">
        <property type="term" value="P:mannose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009313">
        <property type="term" value="P:oligosaccharide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1270.50:FF:000004">
        <property type="entry name" value="alpha-mannosidase 2C1 isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.110.10:FF:000002">
        <property type="entry name" value="alpha-mannosidase 2C1 isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.70.98.30:FF:000001">
        <property type="entry name" value="alpha-mannosidase 2C1 isoform X2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.110.10">
        <property type="entry name" value="Glycoside hydrolase 38, N terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.50">
        <property type="entry name" value="Glycoside hydrolase family 38, central domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.98.30">
        <property type="entry name" value="Golgi alpha-mannosidase II, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054723">
        <property type="entry name" value="Ams1-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011013">
        <property type="entry name" value="Gal_mutarotase_sf_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041147">
        <property type="entry name" value="GH38_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011330">
        <property type="entry name" value="Glyco_hydro/deAcase_b/a-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011682">
        <property type="entry name" value="Glyco_hydro_38_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015341">
        <property type="entry name" value="Glyco_hydro_38_cen"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037094">
        <property type="entry name" value="Glyco_hydro_38_cen_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000602">
        <property type="entry name" value="Glyco_hydro_38_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027291">
        <property type="entry name" value="Glyco_hydro_38_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028995">
        <property type="entry name" value="Glyco_hydro_57/38_cen_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46017">
        <property type="entry name" value="ALPHA-MANNOSIDASE 2C1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46017:SF1">
        <property type="entry name" value="ALPHA-MANNOSIDASE 2C1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09261">
        <property type="entry name" value="Alpha-mann_mid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22907">
        <property type="entry name" value="Ams1-like_1st"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17677">
        <property type="entry name" value="Glyco_hydro38C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07748">
        <property type="entry name" value="Glyco_hydro_38C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01074">
        <property type="entry name" value="Glyco_hydro_38N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00872">
        <property type="entry name" value="Alpha-mann_mid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88688">
        <property type="entry name" value="Families 57/38 glycoside transferase middle domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74650">
        <property type="entry name" value="Galactose mutarotase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88713">
        <property type="entry name" value="Glycoside hydrolase/deacetylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glycoside hydrolase family 38 central" evidence="9">
        <location>
            <begin position="527"/>
            <end position="610"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000365"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012752"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00054985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00071615"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00872"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OBZ84712.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="1072" mass="122148" checksum="228FA095321ADB36" modified="2016-11-30" version="1">MRPALDNAPRVPNNIAQSRINNFLAGSGQFYGMGIQRGLWAIRKKGPPHVQLKVYSVPELKRISFKEAVAQEFEDFTLGQKDFGPSWSTHWFRILVRIPSELDGHKVVFQWDMGSEGMVWSKKGVPLQGLTGGLDQARHEYILTNHAKEGDVFEFYIEAACNGMFGVGNGDSMVAFPNRYFCLEKADLVVPNEPIQRLFHDLTVLRGIGFDTDSSSPRARQALWVINEVINRFICDDEDSIKSCLDLTQGYLNAKNGVGQHKITAVGNCHIDTAWLWPYDETKRKIARSWSSQLDLIERYPEYVFTGSQVQQYEWLKELYHPVFEKIQHAEKSGQWEIIGGSWVEHDTNMPSGESLCRQMLLGQKFFEKHFGKRTRVFWLPDSFGYSAQLPQVLRESGCDYFFTQKLSWNNINKFPLSTFWWTGIDDTSILAHLTPAETYTASVTPAELYKCAKNHHDLEFTNESLLVYGHGDGGGGPTPEMLERLRRMKNVDGLPSVKTGSATSFFEGLEKHADRLQXYKGELYLEFHRGTYTSQALVKRGNRKGEVIIRDVEFLATAAKLLANESKASYSYPVEDIERLWKLLCLNQFHDCLPGSAINLAYVDVHKFHRQVISESSLLRHKAQTLLISESCQPKEGRDPKAKGVVVFNTLPWPRSDVIMCPEKNTKWVNQQWKDNYEYLLVNEVPGLGASGYIETDDMKPIPPERSAHAYVTKTGYFVIENFNLKATFNSNGQLIELEDKKFDRGNLIPKDKKGNVLQLYEDVPTYWDAWDVEIYHLQKYVDLQGQHTLKVLSDGPIKAELCFEHKISDVSSIKQIISLTCVGKRIEFENFVDWHESHQFLKVEFNWDIVTDFATYDIQYGVVRRPTHHNTTIDSAKFEVCGHKFADLSESNYGVALLNDCKYGYATHGKTQRLSLLRAPKGPDEHADMGQHKFKYAIYPHQGNYSSSDVMQAALEFNTPLSVRVANSTEIQSGPFIPSLFTIEKSQQIIIDTIKLSEDDKGKGKQVILRLYEAYGGRSTGVLKSRLNVKRAQISNVLEDSTDRELEKKHGGFLVTLKAFQILTLKVDLH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N6V2</accession>
    <name>A0A1C7N6V2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_07104</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000462">
        <property type="protein sequence ID" value="OBZ84850.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N6V2"/>
    <dbReference type="InParanoid" id="A0A1C7N6V2"/>
    <dbReference type="OrthoDB" id="2283494at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ84850.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="255" mass="28483" checksum="40897875E3E73F58" modified="2016-11-30" version="1">MSTALNNSSNNSIQQDSNLIVSLAELYDSIVLEKKWKLKSGRYAEDVLRGFALKCAVEHPSQSLILDLYDTNLAGVFTQEEEEILAEGGFPLENDLDTAYREILNSLVGQSKYDELEEVIEKIEAKGRSDFAKKMFEDEDEILYSLWSFIKTLLIGTGGEVHGHAQANEVSTSTNEGGIMPIRRKQSCEIPDMSFQYLNRHLGCLEIGAQSGEYETKTLQEAYFKCPLMLKNQASALSSNMKQVGIVIDSTTCKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N7L5</accession>
    <name>A0A1C7N7L5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Transcription initiation factor TFIID subunit 14</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">TAF14_0</name>
        <name evidence="5" type="ORF">A0J61_06899</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000439">
        <property type="protein sequence ID" value="OBZ85051.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N7L5"/>
    <dbReference type="STRING" id="101091.A0A1C7N7L5"/>
    <dbReference type="InParanoid" id="A0A1C7N7L5"/>
    <dbReference type="OrthoDB" id="1741717at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008023">
        <property type="term" value="C:transcription elongation factor complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003682">
        <property type="term" value="F:chromatin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045893">
        <property type="term" value="P:positive regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd16905">
        <property type="entry name" value="YEATS_Taf14_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1970">
        <property type="entry name" value="YEATS domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038704">
        <property type="entry name" value="YEAST_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055129">
        <property type="entry name" value="YEATS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052790">
        <property type="entry name" value="YEATS_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47827:SF3">
        <property type="entry name" value="AF-9 ANC1 HOMOLOGY DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47827">
        <property type="entry name" value="AHD DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03366">
        <property type="entry name" value="YEATS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51037">
        <property type="entry name" value="YEATS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="1 2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="YEATS" evidence="4">
        <location>
            <begin position="1"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="139"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="272"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="397"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="159"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="207"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="248"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="276"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="412"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="482"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="unsure residue" description="D or N" evidence="5">
        <location>
            <position position="490"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00376"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51037"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OBZ85051.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="492" mass="55487" checksum="0300141FFB418127" modified="2016-11-30" version="1">MAIVTQDIRISCQNSVIKGSGAKSNEGHPWRNWKITLVAMDGEKEVKGKLSVILDHVEYILHPTFEEPRRVKKEEPYILQEKGWGEFDMRVVLYFTENITDPQVLLFDLNFALSNYSITHTVKFPNASPELIELLSREPLPRKGGKKPMSTVQPPPPLQVSQSLPPSTSHSSTSPTKAKKSSSERTSKKKPVTNSPQTSKVASKKAKSSDTKRKSSLDSKPVAISQSNHRMYSSPSPLIPPPSSSQSTTTLARSPSFTDLSPMQISVQPILSTPESSHHIQERNRSLEDATETPAEHVYNLSDVYNLNPIHHAKIDRSVRDKWNIPQINMMELAKRMYGMTAEQNEEVQRLIVRYQSDTIKTVVGEDASVGIDLYSLGKPLLEKIWDCLADMASDDNESFTSQDHHPSDLEFGSDIEMGEYNSDEGELFDDNRPLSDMDEPGFHMSDFESDQEHRLNGYPVENGYHYHRQHISDNPIASDMDMQEGDEDDDY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N7N3</accession>
    <name>A0A1C7N7N3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Meiosis-specific transcription factor NDT80</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">NDT80_1</name>
        <name evidence="5" type="ORF">A0J61_08599</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000679">
        <property type="protein sequence ID" value="OBZ83344.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N7N3"/>
    <dbReference type="STRING" id="101091.A0A1C7N7N3"/>
    <dbReference type="InParanoid" id="A0A1C7N7N3"/>
    <dbReference type="OrthoDB" id="2288358at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000228">
        <property type="term" value="C:nuclear chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051321">
        <property type="term" value="P:meiotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1390">
        <property type="entry name" value="NDT80 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052605">
        <property type="entry name" value="Fungal_trans_regulator"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024061">
        <property type="entry name" value="NDT80_DNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037141">
        <property type="entry name" value="NDT80_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008967">
        <property type="entry name" value="p53-like_TF_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35144">
        <property type="entry name" value="MEIOSIS-SPECIFIC TRANSCRIPTION FACTOR NDT80"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35144:SF2">
        <property type="entry name" value="MEIOSIS-SPECIFIC TRANSCRIPTION FACTOR NDT80"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05224">
        <property type="entry name" value="NDT80_PhoG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49417">
        <property type="entry name" value="p53-like transcription factors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51517">
        <property type="entry name" value="NDT80"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NDT80" evidence="4">
        <location>
            <begin position="65"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="NDT80" evidence="2">
        <location>
            <begin position="65"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="19"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="328"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="410"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="469"/>
            <end position="488"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="27"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="40"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="89"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="328"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="357"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="410"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="476"/>
            <end position="485"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OBZ83344.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="520" mass="58428" checksum="988C9C7AE26D5440" modified="2016-11-30" version="1">MQPNKWPSIQPEAMTSYVPLPYYNNGEYPSNDPSSGSEASSQLPVSSPLQPGILSMSQPETPRPESPSSLPPVPSNASLPNNKMIGQPSMPSRSSSYTTTFHSIPYSNPGPIRRRRTDSFFSFETGPTFTETRQHYDLCSLDQTNNFQVHLYAKMDRGFFRADQDWTCYRRNYFQVSSVFEIQGTNYELRGPEVPCLLRKPDIQEWLQVEYFSIGISARIASNDKKIEIVQHTPKRDKGPQIIPEPRIVRAGGNLHLASVGANHNIVTFERLQFKTATANNGKRRAAQQYYEIVIDLYANFSNQPPLCVASCSSAPLVVRGRSPGHYADSHTRFRHNNHEDIDSQRPPQSIPMAPDVSNSTHSTLDNNEQSSPNTSTHYSSIPNSPISDFGPYPGYQGYPYPSLSTGYSSMMSSQPMSQYPSSQPNPSHFQHHALPPPAPPTPSSHMYHNYQFNGSKVSKQDTEKMNTDYWSSPQHDPRIHHEAPHYPAGNHMYMASYQSRLHQQEDNHSGFSGIDAGRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N7Q1</accession>
    <name>A0A1C7N7Q1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Rho-related GTP-binding protein RhoB</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">Rhob</name>
        <name evidence="10" type="ORF">A0J61_08587</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Lipid-anchor</topology>
            <orientation evidence="1">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the small GTPase superfamily. Rho family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000676">
        <property type="protein sequence ID" value="OBZ83364.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N7Q1"/>
    <dbReference type="STRING" id="101091.A0A1C7N7Q1"/>
    <dbReference type="InParanoid" id="A0A1C7N7Q1"/>
    <dbReference type="OrthoDB" id="8830751at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007264">
        <property type="term" value="P:small GTPase-mediated signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000983">
        <property type="entry name" value="Rho family GTPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001806">
        <property type="entry name" value="Small_GTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003578">
        <property type="entry name" value="Small_GTPase_Rho"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24072">
        <property type="entry name" value="RHO FAMILY GTPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00071">
        <property type="entry name" value="Ras"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00449">
        <property type="entry name" value="RASTRNSFRMNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00175">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00173">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00174">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51419">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51421">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51420">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="8" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0488">Methylation</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-0636">Prenylation</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004342"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010142"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023289"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OBZ83364.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="195" mass="22060" checksum="D0FF45D2092F1505" modified="2016-11-30" version="1">MQRLSRKKLVVVGDGFCGKTSLLHVFQHNEFPEDYVPTVFENYISIINHESGKSIELSLWDTAGQEDYDRLRPLCYPETDVILVCFAIDQVQSFMNVKDTWIPEMDHFLFNVPRLLVGTKSDLRTDAARIAELRANGQQLISVEQAEALARTLKMQYIECSARTNTNVAKVIHTATGLILSNRKGGLKTKICTLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N8A3</accession>
    <name>A0A1C7N8A3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_06603</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000406">
        <property type="protein sequence ID" value="OBZ85352.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N8A3"/>
    <dbReference type="InParanoid" id="A0A1C7N8A3"/>
    <dbReference type="OrthoDB" id="10291024at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="59"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="67"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="78"/>
            <end position="90"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ85352.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="90" mass="10033" checksum="509DEFCF6D5A1C57" modified="2016-11-30" version="1">MNSNESTEQPLKSSKYNINNAFDFDITSYSSLIVDSCSIHPLQTTDEAYAIDISRTSPKQKEGQLSAMMSNLSLTKTDSTDKDKPMPYCL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N8J3</accession>
    <name>A0A1C7N8J3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">fumarate reductase (NADH)</fullName>
            <ecNumber evidence="10">1.3.1.6</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">NADH-dependent fumarate reductase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="primary">osm1_1</name>
        <name evidence="14" type="ORF">A0J61_06507</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>succinate + NAD(+) = fumarate + NADH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:18281"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29806"/>
            <dbReference type="ChEBI" id="CHEBI:30031"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.3.1.6"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.3.1.6" evidence="10"/>
    <dbReference type="EMBL" id="LUGH01000395">
        <property type="protein sequence ID" value="OBZ85445.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N8J3"/>
    <dbReference type="FunCoup" id="A0A1C7N8J3">
        <property type="interactions" value="20"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N8J3"/>
    <dbReference type="InParanoid" id="A0A1C7N8J3"/>
    <dbReference type="OrthoDB" id="10252157at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016156">
        <property type="term" value="F:fumarate reductase (NADH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.700.10:FF:000007">
        <property type="entry name" value="NADH-dependent fumarate reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.120.10:FF:000007">
        <property type="entry name" value="Sulfite oxidase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.120.10">
        <property type="entry name" value="Cytochrome b5-like heme/steroid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.700.10">
        <property type="entry name" value="Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001199">
        <property type="entry name" value="Cyt_B5-like_heme/steroid-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036400">
        <property type="entry name" value="Cyt_B5-like_heme/steroid_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018506">
        <property type="entry name" value="Cyt_B5_heme-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003953">
        <property type="entry name" value="FAD-dep_OxRdtase_2_FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050315">
        <property type="entry name" value="FAD-oxidoreductase_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010960">
        <property type="entry name" value="Flavocytochrome_c"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027477">
        <property type="entry name" value="Succ_DH/fumarate_Rdtase_cat_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01813">
        <property type="entry name" value="flavo_cyto_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43400">
        <property type="entry name" value="FUMARATE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43400:SF1">
        <property type="entry name" value="FUMARATE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00173">
        <property type="entry name" value="Cyt-b5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00890">
        <property type="entry name" value="FAD_binding_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00363">
        <property type="entry name" value="CYTOCHROMEB5"/>
    </dbReference>
    <dbReference type="SMART" id="SM01117">
        <property type="entry name" value="Cyt-b5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55856">
        <property type="entry name" value="Cytochrome b5-like heme/steroid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56425">
        <property type="entry name" value="Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00191">
        <property type="entry name" value="CYTOCHROME_B5_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50255">
        <property type="entry name" value="CYTOCHROME_B5_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0274">FAD</keyword>
    <keyword evidence="4" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="3" id="KW-0349">Heme</keyword>
    <keyword evidence="8" id="KW-0408">Iron</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cytochrome b5 heme-binding" evidence="13">
        <location>
            <begin position="560"/>
            <end position="636"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="517"/>
            <end position="548"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="526"/>
            <end position="545"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00050832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00067004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00077246"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="OBZ85445.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="637" mass="68784" checksum="A22A3290B711BE60" modified="2016-11-30" version="1">MSLQNQIIVVGGGLSGLSAAHTVYEQGGNVLLLDKNPYFGGNSTKATSGINGALTRTQVALNIQDSVEQFFQDTLKSARDLARPDLIRVLTGRSASAVEWLQDKFELDLSLVSRLGGHSFPRTHRGKEQFPGMTITYALMEGLEDLAKSQPNRAKIIKKAKVTNLIKDAEGNVIGVEYVLVGKDATGEVLKEYGPVILATGGYAADFTDNDSLLKKHRPELYNLSTTNGDHCTGDGIKMAAAIGASTIDLEKVQVHPTGLVDPKEPDAKVKFLAAEALRGCGGILLDADGKRFCDELGHRDYVTGMMNKNKFPIRLVLNTAASKEIEWHCRHYAGRGLMKRFDSGEALAKEMGISPKQLEETFETYNKIAEGKEKDPWGKRFFHNVPIKMSDYFYVALMQPVLHYTMGGVEITPDAEIKSTDGKPIPGLFATGEMCGGVHGANRLGGSSLLGCVVFGRVAGQTAAKHLFSQLVNKTQMAQQRLGAIGQHLNGGVGINIVFNPTQPNVISMDISLPQGGAGGQQVGPSTNALPSSSTSPSAVVKPTTQDEIKQAEEPKKKMGEYTLEDVAKHNKPEDCWVVVNGQVLDVTDFLPDHPGGKKAILIYAGRDATEEFNMLHKPDVVEKYAPSAIIGTLKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N9F2</accession>
    <name>A0A1C7N9F2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Calcium/calmodulin-dependent protein kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">cmkA_0</name>
        <name evidence="10" type="ORF">A0J61_06692</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="7">Belongs to the protein kinase superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000417">
        <property type="protein sequence ID" value="OBZ85256.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N9F2"/>
    <dbReference type="STRING" id="101091.A0A1C7N9F2"/>
    <dbReference type="InParanoid" id="A0A1C7N9F2"/>
    <dbReference type="OrthoDB" id="40902at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05117">
        <property type="entry name" value="STKc_CAMK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000315">
        <property type="entry name" value="Calcium-dependent protein kinase 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000026">
        <property type="entry name" value="Calcium/calmodulin-dependent protein kinase type 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24347">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 10" id="KW-0418">Kinase</keyword>
    <keyword evidence="3 6 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 7" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="9">
        <location>
            <begin position="27"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="342"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="345"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="56"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OBZ85256.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="362" mass="40589" checksum="45D9AED33ECE9D1A" modified="2016-11-30" version="1">MGLFKALDAIVHGGVSQPDSYEKKKEYTFGEILGSGSFGSVRKAVRLSDNKEVAIKVIPKRNVKNHLDMVKDEVDVLKNLNHPNVIGFYDTFESRDKFYLVFELATGGELFERLFERGKFTEKDAVAIIHSVLKGVEYLHKNNIVHRDMKPENLLFKTPESDSDLVICDFGIAKSSSETSPLETVCGSPGYVAPEVILKKGYGPAIDMWAVGVITYTLLCGYQPFQAEDQVELMDEITHARFEFHERYWRNISIEAKDFIRALLTLDDKKRLTATEAMQHKWMTSNSATDIDILDTVRTNFNPRRTLKSAVSAIRAMNRLKTSSMIVDKSSELVASLKITEEANHPSNSSSGTTVPAVAEVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N9U7</accession>
    <name>A0A1C7N9U7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_07825</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000552">
        <property type="protein sequence ID" value="OBZ84124.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N9U7"/>
    <dbReference type="InParanoid" id="A0A1C7N9U7"/>
    <dbReference type="OrthoDB" id="2289903at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008889563" evidence="2">
        <location>
            <begin position="19"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="89"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="116"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ84124.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="116" mass="12051" checksum="D658296ED9A87386" modified="2016-11-30" version="1" fragment="single">MKSTILLSISLLIASVSAACNCKPSEQACIDTCVKTANACVTQCNTHNPSKECINGCIAATWPTSITLPDQKVTLDIKNTTSVATLSHAPSQSIVASKSTGSILPTTSPKTNLETN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NA05</accession>
    <name>A0A1C7NA05_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Ribonuclease P/MRP protein subunit POP5</fullName>
            <ecNumber evidence="5">3.1.26.5</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">A0J61_05989</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Component of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>Endonucleolytic cleavage of RNA, removing 5'-extranucleotides from tRNA precursor.</text>
            <dbReference type="EC" id="3.1.26.5"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the eukaryotic/archaeal RNase P protein component 2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.26.5" evidence="5"/>
    <dbReference type="EMBL" id="LUGH01000342">
        <property type="protein sequence ID" value="OBZ85955.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NA05"/>
    <dbReference type="FunCoup" id="A0A1C7NA05">
        <property type="interactions" value="171"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NA05"/>
    <dbReference type="InParanoid" id="A0A1C7NA05"/>
    <dbReference type="OrthoDB" id="24745at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030681">
        <property type="term" value="C:multimeric ribonuclease P complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000172">
        <property type="term" value="C:ribonuclease MRP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004526">
        <property type="term" value="F:ribonuclease P activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033204">
        <property type="term" value="F:ribonuclease P RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001682">
        <property type="term" value="P:tRNA 5'-leader removal"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.3250">
        <property type="entry name" value="Ribonuclease P, Pop5 subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002759">
        <property type="entry name" value="Pop5/Rpp14/Rnp2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016819">
        <property type="entry name" value="RNase_P/MRP_POP5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038085">
        <property type="entry name" value="Rnp2-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15441">
        <property type="entry name" value="RIBONUCLEASE P PROTEIN SUBUNIT P14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15441:SF2">
        <property type="entry name" value="RIBONUCLEASE P_MRP PROTEIN SUBUNIT POP5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01900">
        <property type="entry name" value="RNase_P_Rpp14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF023803">
        <property type="entry name" value="Ribonuclease_P_prd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160350">
        <property type="entry name" value="Rnp2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0819">tRNA processing</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010800"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRNR" id="PIRNR023803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OBZ85955.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="156" mass="18133" checksum="49746A40DD871F94" modified="2016-11-30" version="1">MVRFKNRWVLFQIIEDPILEQGKVVFPKTQFSVNDTIITKAIFQAIETNYGHFGKGQGNVTVKWYNPMTRVGILRIPRDYTDMYLSTMFFMKQIGNMACSFSILRVSGTIIFIQQAAIEWDRQFYLKEQAEAEKKGEHYNATEKIMNSKEIISALS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NAC8</accession>
    <name>A0A1C7NAC8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="8">DNA polymerase alpha-associated DNA helicase A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">hcs1_0</name>
        <name evidence="8" type="ORF">A0J61_05983</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the DNA2/NAM7 helicase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000341">
        <property type="protein sequence ID" value="OBZ85970.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NAC8"/>
    <dbReference type="InParanoid" id="A0A1C7NAC8"/>
    <dbReference type="OrthoDB" id="6513042at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005694">
        <property type="term" value="C:chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043139">
        <property type="term" value="F:5'-3' DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd18044">
        <property type="entry name" value="DEXXQc_SMUBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18808">
        <property type="entry name" value="SF1_C_Upf1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000326">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050534">
        <property type="entry name" value="Coronavir_polyprotein_1ab"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041679">
        <property type="entry name" value="DNA2/NAM7-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041677">
        <property type="entry name" value="DNA2/NAM7_AAA_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047187">
        <property type="entry name" value="SF1_C_Upf1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43788:SF8">
        <property type="entry name" value="DNA-BINDING PROTEIN SMUBP-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43788">
        <property type="entry name" value="DNA2/NAM7 HELICASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13086">
        <property type="entry name" value="AAA_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13087">
        <property type="entry name" value="AAA_12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0347">Helicase</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA2/NAM7 helicase helicase" evidence="6">
        <location>
            <begin position="325"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="domain" description="DNA2/NAM7 helicase-like C-terminal" evidence="7">
        <location>
            <begin position="416"/>
            <end position="615"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF13086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF13087"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OBZ85970.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="671" mass="75227" checksum="865E3A63CB9F517B" modified="2016-11-30" version="1">MVSKLIKIFKYLLSSNGASDIESFDDQSSNGTIQDPQRSQDYIQHLIELTRKESEQEKPPVEPLPVLVKKGIAVCNLKIKESQPSVAGLHKLVLGLERTIIGKEVAIPPHKITKGNIVSLSKYNPYSNSIGGEIQATVAEVKKFRIHLILYNDFDSLPSSLMGACQMMLNALYNLKIKDKLSSYNSLASVLLEKETPILPSIHRDKLIPFDWKLNKYQKEAASFAIASPEIALIHGPPGNRLKTTDFKSVLVETGKTQTLVEVIRQLHKQRKKILVSGPSNVAVDNLMERIAKHKDMDIIRVGNLARVSQEVIPYCLDKLAPKDSQKREMAAELVSNADVIFSTLSGAGCKDLNPIEFDVIIIDEASQATEPDCWVALLKGKKAILAGDHLQLAPTVLSTMDNAVKEKGMSVRNTLSYSLFDRMLDTYGDRIKRMLEVQYRMNTDIMYFSSANLYNNKLVAHPSVEDHRLHELQHVVKNDDTTATIALYDTSSFANAKEQKNKQFDDGSYYNLKEVSIIVDVVHKLLKYGVKKKEVGIITPYSAQVRYLQDGMGDQLEEIEVGSVDGFQGREKEVIVLSMVRSNERGQVGFLSEKRRLNVAITRAKRQLIVVGNMRTLKGRGVISSQDNGFISKWAKWLTDKAEEDSTLCCTTITKAKKRNIKAYLNKDHH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NB91</accession>
    <name>A0A1C7NB91_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Protein BUD31</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">BUD31</name>
        <name evidence="4" type="ORF">A0J61_05699</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the BUD31 (G10) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000315">
        <property type="protein sequence ID" value="OBZ86260.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NB91"/>
    <dbReference type="FunCoup" id="A0A1C7NB91">
        <property type="interactions" value="612"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NB91"/>
    <dbReference type="InParanoid" id="A0A1C7NB91"/>
    <dbReference type="OrthoDB" id="277109at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071014">
        <property type="term" value="C:post-mRNA release spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000974">
        <property type="term" value="C:Prp19 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005686">
        <property type="term" value="C:U2 snRNP"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005684">
        <property type="term" value="C:U2-type spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001748">
        <property type="entry name" value="BUD31"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018230">
        <property type="entry name" value="BUD31/G10-rel_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19411:SF0">
        <property type="entry name" value="PROTEIN BUD31 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19411">
        <property type="entry name" value="PROTEIN BUD31-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01125">
        <property type="entry name" value="BUD31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00322">
        <property type="entry name" value="G10"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00997">
        <property type="entry name" value="G10_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00998">
        <property type="entry name" value="G10_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005287"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OBZ86260.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="147" mass="17409" checksum="260561FFB91F6FF0" modified="2016-11-30" version="1">MPKIRTSRTKRPPEGFDEIEPTLEEFSRKMREVENESHEGKRIVESSWPVFRIHHQRSRYIYDLFYKRKLISRELYDYLLKNKYADANLIAKWKKPGFEKLCCLRCIQPKDTNFGTTCICRVPKEKLEEGKMIECVHCGCRGCASGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NBD8</accession>
    <name>A0A1C7NBD8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Protein ERD1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">ERD1</name>
        <name evidence="7" type="ORF">A0J61_05599</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000307">
        <property type="protein sequence ID" value="OBZ86351.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NBD8"/>
    <dbReference type="STRING" id="101091.A0A1C7NBD8"/>
    <dbReference type="InParanoid" id="A0A1C7NBD8"/>
    <dbReference type="OrthoDB" id="2159384at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004342">
        <property type="entry name" value="EXS_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10783:SF46">
        <property type="entry name" value="PROTEIN ERD1 HOMOLOG 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10783">
        <property type="entry name" value="XENOTROPIC AND POLYTROPIC RETROVIRUS RECEPTOR 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03124">
        <property type="entry name" value="EXS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51380">
        <property type="entry name" value="EXS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="65"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="140"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="domain" description="EXS" evidence="6">
        <location>
            <begin position="1"/>
            <end position="223"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51380"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OBZ86351.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="234" mass="28418" checksum="AEBE7CFF2A6062CB" modified="2016-11-30" version="1">MPYLIRLKQCVAEYLESKERRHIFNALKYASSIPVVIFSAVQRKAIMYITEVGSVPQYWYLKEDAIFRFWIMFVFINSMYSFWWDISMDWNLVTVQLDPTEINDHHQPQLKHHNKVIRHPPQITTPMIHFRRQLYFSQPFWYVLSIFFDFLLRITWSLKLSSHIYLRKLDGSIFLMELLEIFRRWVWVIFRLESEWVKKVYNSLPNAAFENLRMNLLDRRSSGTLSPIVEEEDP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NCH8</accession>
    <name>A0A1C7NCH8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Vacuolar calcium ion transporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">VCX1_0</name>
        <name evidence="13" type="ORF">A0J61_05179</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Has a role in promoting intracellular calcium ion sequestration via the exchange of calcium ions for hydrogen ions across the vacuolar membrane. Involved also in manganese ion homeostasis via its uptake into the vacuole.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="10">Vacuole membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000273">
        <property type="protein sequence ID" value="OBZ86771.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NCH8"/>
    <dbReference type="STRING" id="101091.A0A1C7NCH8"/>
    <dbReference type="InParanoid" id="A0A1C7NCH8"/>
    <dbReference type="OrthoDB" id="1699231at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000329">
        <property type="term" value="C:fungal-type vacuole membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015369">
        <property type="term" value="F:calcium:proton antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006874">
        <property type="term" value="P:intracellular calcium ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1420.30:FF:000011">
        <property type="entry name" value="Vacuolar calcium ion transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1420.30">
        <property type="entry name" value="NCX, central ion-binding region"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004713">
        <property type="entry name" value="CaH_exchang"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004798">
        <property type="entry name" value="CAX-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004837">
        <property type="entry name" value="NaCa_Exmemb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044880">
        <property type="entry name" value="NCX_ion-bd_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00846">
        <property type="entry name" value="caca2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00378">
        <property type="entry name" value="cax"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31503:SF20">
        <property type="entry name" value="CA(2+)_H(+) EXCHANGER, PUTATIVE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31503">
        <property type="entry name" value="VACUOLAR CALCIUM ION TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01699">
        <property type="entry name" value="Na_Ca_ex"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0050">Antiport</keyword>
    <keyword evidence="6 10" id="KW-0106">Calcium</keyword>
    <keyword evidence="4 10" id="KW-0109">Calcium transport</keyword>
    <keyword evidence="8 10" id="KW-0406">Ion transport</keyword>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 10" id="KW-0813">Transport</keyword>
    <keyword evidence="10" id="KW-0926">Vacuole</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="60"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="85"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="114"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="141"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="184"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="222"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="284"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="321"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="351"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="384"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="412"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="domain" description="Sodium/calcium exchanger membrane region" evidence="12">
        <location>
            <begin position="82"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="domain" description="Sodium/calcium exchanger membrane region" evidence="12">
        <location>
            <begin position="287"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="253"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="9"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="36"/>
            <end position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022568"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU365028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF01699"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="OBZ86771.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="454" mass="49407" checksum="CF328716DA68F7C0" modified="2016-11-30" version="1">MEKQENHENSSITTMDQSAMSSTPIAQTQPSVSNLSQQQQQKKTKQISTKDGLMTIIKSSWLNVMLVFVPIGIASHFVWPPTVTFIMNFLAIVPLAKLLGFATEDIALRTGEVIGGLLNATFGNAVELIISIISLTQNLVVVVQASMLGSILSNLLLVLGMCFMGGGYYHKVQYFNRTVAQTSASLLFISVASLLIPASFYGSIHSADSESPAILSQDILNISRATSIILLILYFSYLFFQLSTHKHLFMGPSSPEVSQISQHDQEQGQTEEEEEEIEEPQLPAWMAIALLIIVTVIVGVCAEFLVSAIEEVTELWHISETFVGLILLPIVGNAAEHLTAVTCAMKNKMDLALGVAVGSSMQIALLVTPLMVIIGWGMNVNMSLFFNIYETAVLLIAVIMVNYLIMDGESNWLEGLMLIAVYIVIAISFYYYPDETSAAVTSQATGVNSTVSAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NCN0</accession>
    <name>A0A1C7NCN0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Putative vacuolar amino acid transporter YPQ1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">YPQ1</name>
        <name evidence="9" type="ORF">A0J61_05619</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>L-histidine(out) + L-arginine(in) = L-histidine(in) + L-arginine(out)</text>
            <dbReference type="Rhea" id="RHEA:71063"/>
            <dbReference type="ChEBI" id="CHEBI:32682"/>
            <dbReference type="ChEBI" id="CHEBI:57595"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the laat-1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000308">
        <property type="protein sequence ID" value="OBZ86336.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NCN0"/>
    <dbReference type="FunCoup" id="A0A1C7NCN0">
        <property type="interactions" value="125"/>
    </dbReference>
    <dbReference type="InParanoid" id="A0A1C7NCN0"/>
    <dbReference type="OrthoDB" id="8048523at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098852">
        <property type="term" value="C:lytic vacuole membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015174">
        <property type="term" value="F:basic amino acid transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034486">
        <property type="term" value="P:vacuolar transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1280.290:FF:000009">
        <property type="entry name" value="PQ loop repeat family protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1280.290:FF:000012">
        <property type="entry name" value="Vacuolar membrane PQ loop repeat protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.290">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051415">
        <property type="entry name" value="LAAT-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006603">
        <property type="entry name" value="PQ-loop_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16201:SF44">
        <property type="entry name" value="SEVEN TRANSMEMBRANE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16201">
        <property type="entry name" value="SEVEN TRANSMEMBRANE PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04193">
        <property type="entry name" value="PQ-loop"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00679">
        <property type="entry name" value="CTNS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="6"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="39"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="65"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="146"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="218"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="252"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="119"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038039"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00050768"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OBZ86336.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="285" mass="32661" checksum="13F398FE0C189628" modified="2016-11-30" version="1">MMDHTLASSVAGYLSILCWLIVFTPQLWENYRRKSGDGLSMTFLVIWLAGDVFNLLGVIMQDLLVTMFVLALYYTVADMALIWQVIYYRRTRKQHSKQLALADEEALSQDQQETSGLLNHTQPVDYDTSSPKHHQRNSTKDDSTSALNLVSAISVLAVTVFSCYAYYRAHWHNHHDDQGELNRFNWLPQLMGWSSAVLYVGSRVPQILKNWRNKSTEGLSFGMFLCAVMGNVFFTSSIFLKSTQLDYIIVNLSWIVGSCGTLLFDFVIFLQFFAYDNDRKDKIVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7ND22</accession>
    <name>A0A1C7ND22_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">MYND-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">A0J61_05019</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000260">
        <property type="protein sequence ID" value="OBZ86928.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7ND22"/>
    <dbReference type="InParanoid" id="A0A1C7ND22"/>
    <dbReference type="OrthoDB" id="412876at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.2220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002893">
        <property type="entry name" value="Znf_MYND"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01753">
        <property type="entry name" value="zf-MYND"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144232">
        <property type="entry name" value="HIT/MYND zinc finger-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50865">
        <property type="entry name" value="ZF_MYND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="MYND-type" evidence="5">
        <location>
            <begin position="241"/>
            <end position="279"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OBZ86928.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="281" mass="32068" checksum="405F885A92A4E871" modified="2016-11-30" version="1">MPSIVLSKVAIAQEEIPNTDFSKCLQRTTEAASTINQKHDSLSECHQCHEIANQYLLGFQWVKQQPTLVCNAPLLKLVQQSVELIRNHIDMARVQHLVWVPVLMNTLRELGKTIKDECSESDRMVSLPLCIESESEEEQLYNHSTKRGTSSHEDYGRAIRITIYYCRASMCEELDLPKSIHYYRKCISVRPSQYESQPFQVSARTALQHLIAEQYHNKRPSLTSRTSSISSITTSSCSMACANCGVEKRAMPVCSRCKSQYYCSIQCLKIHKPVHQIDCHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7ND91</accession>
    <name>A0A1C7ND91_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">SH3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">A0J61_04900</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000251">
        <property type="protein sequence ID" value="OBZ87041.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7ND91"/>
    <dbReference type="STRING" id="101091.A0A1C7ND91"/>
    <dbReference type="InParanoid" id="A0A1C7ND91"/>
    <dbReference type="OrthoDB" id="27823at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.40">
        <property type="entry name" value="SH3 Domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036028">
        <property type="entry name" value="SH3-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001452">
        <property type="entry name" value="SH3_domain"/>
    </dbReference>
    <dbReference type="SMART" id="SM00326">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50044">
        <property type="entry name" value="SH3-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50002">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0728">SH3 domain</keyword>
    <feature type="domain" description="SH3" evidence="3">
        <location>
            <begin position="122"/>
            <end position="188"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OBZ87041.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="188" mass="21274" checksum="FF509CBCA26195BD" modified="2016-11-30" version="1">MHPTNQIEKQLSQVAVYQPITLSDTSTLTHYHEKGDNSSPITSQNAYTNPAKPANNEYYASYSTQAALNSSQPYQPAYSHYLPYSNSTHSRTHVSSTDYAYYSGLKENMYCPPSNIPQGTQPTLFWALALDDWYTGNPEELQYSRGTWLAVTEVQDNGWYFAAKFDPRANCLTNETGYVAQNYVQVYS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NE89</accession>
    <name>A0A1C7NE89_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Protein AAR2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">AAR2</name>
        <name evidence="4" type="ORF">A0J61_04516</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the AAR2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000223">
        <property type="protein sequence ID" value="OBZ87433.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NE89"/>
    <dbReference type="FunCoup" id="A0A1C7NE89">
        <property type="interactions" value="476"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NE89"/>
    <dbReference type="InParanoid" id="A0A1C7NE89"/>
    <dbReference type="OrthoDB" id="201752at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000244">
        <property type="term" value="P:spliceosomal tri-snRNP complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd13778">
        <property type="entry name" value="Aar2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd13777">
        <property type="entry name" value="Aar2_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.34.20:FF:000001">
        <property type="entry name" value="protein AAR2 homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.34.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.550">
        <property type="entry name" value="Aar2, C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007946">
        <property type="entry name" value="AAR2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033648">
        <property type="entry name" value="AAR2_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038514">
        <property type="entry name" value="AAR2_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033647">
        <property type="entry name" value="Aar2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038516">
        <property type="entry name" value="AAR2_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12689">
        <property type="entry name" value="A1 CISTRON SPLICING FACTOR AAR2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12689:SF4">
        <property type="entry name" value="PROTEIN AAR2 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05282">
        <property type="entry name" value="AAR2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20981">
        <property type="entry name" value="AAR2_1st"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAR2 N-terminal" evidence="3">
        <location>
            <begin position="13"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="domain" description="AAR2 C-terminal" evidence="2">
        <location>
            <begin position="188"/>
            <end position="346"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF05282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF20981"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OBZ87433.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="366" mass="42654" checksum="19F5CC8BF287CF1E" modified="2016-11-30" version="1">MDQELANKLFDVGAFLLFLDAPPNLEFGVDYIAWTVGPLFKGIKLIPPGLHFVYFSSTNKEGTSGIRTGFFHFFESQEIVVREWNPQIEDLRDETELDPKQVERLRINIRDFDRNMGPYPLDQPVYYQRWKKLTSYITPGLVRRVLPNNGKVSHLPEKSSDLSALLNETSINDKRLGKSFEREEGMEFTRFDVRRSFPPGATGDEITKWSLDKSWLVKDLLSTVYHDDMRLDYRVMLGELQLAFVCLLMAQNFSGFHQWKQLVHLLCSCSDFMEEKPQLFLEFIDVLETQLEECPDDFYRDILSENNFTSIMLKTLKGNIPGSNEELVKKYGRLQRFLIEKFGWEVPEEDEADEDDEDAPVIVEME</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NEL1</accession>
    <name>A0A1C7NEL1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">2-dehydropantoate 2-reductase</fullName>
            <ecNumber evidence="4">1.1.1.169</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">Ketopantoate reductase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">A0J61_04428</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>(R)-pantoate + NADP(+) = 2-dehydropantoate + NADPH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:16233"/>
            <dbReference type="ChEBI" id="CHEBI:11561"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15980"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.1.1.169"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the ketopantoate reductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.169" evidence="4"/>
    <dbReference type="EMBL" id="LUGH01000216">
        <property type="protein sequence ID" value="OBZ87527.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NEL1"/>
    <dbReference type="FunCoup" id="A0A1C7NEL1">
        <property type="interactions" value="295"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NEL1"/>
    <dbReference type="InParanoid" id="A0A1C7NEL1"/>
    <dbReference type="OrthoDB" id="3609at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008677">
        <property type="term" value="F:2-dehydropantoate 2-reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015940">
        <property type="term" value="P:pantothenate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1040.10:FF:000017">
        <property type="entry name" value="2-dehydropantoate 2-reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000609">
        <property type="entry name" value="2-dehydropantoate 2-reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1040.10">
        <property type="entry name" value="N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008927">
        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013328">
        <property type="entry name" value="6PGD_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003710">
        <property type="entry name" value="ApbA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013752">
        <property type="entry name" value="KPA_reductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051402">
        <property type="entry name" value="KPR-Related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013332">
        <property type="entry name" value="KPR_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00745">
        <property type="entry name" value="apbA_panE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21708:SF30">
        <property type="entry name" value="2-DEHYDROPANTOATE 2-REDUCTASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21708">
        <property type="entry name" value="PROBABLE 2-DEHYDROPANTOATE 2-REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02558">
        <property type="entry name" value="ApbA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08546">
        <property type="entry name" value="ApbA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48179">
        <property type="entry name" value="6-phosphogluconate dehydrogenase C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4" id="KW-0521">NADP</keyword>
    <keyword evidence="3 4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ketopantoate reductase N-terminal" evidence="5">
        <location>
            <begin position="10"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="domain" description="Ketopantoate reductase C-terminal" evidence="6">
        <location>
            <begin position="186"/>
            <end position="310"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007870"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU362068"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF02558"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF08546"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OBZ87527.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="317" mass="35153" checksum="5AD8FFB64AA40F02" modified="2016-11-30" version="1">MSSRPRVLNVGAGAVGAIYSWRLAKTCDVTTVCRSNYQAVKDNGFDIDSAKFGKEIFRPHQVVRYVEDCNGDPFDYILVTMKALPECYNVADIIAPAVSEKTTIVLIQNGLGVEEPITERFPNNPIVSIVAYIGTSQTGLGKISMVGKETLVIGKYLNAKTDSDKQREAFVELLKQGDVDVSVVEDVERVRWQKLFWNTAFSSVCATTGMNTTECLNNPEAMKVVRNVMSEVIDAANAHDYQFDHDAEMRTMIARTEATAQNYKPSMQLDRERNSPMEVEVILGSPLKRARAKGLAVPHLETMHAILSAINAQMIKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NFD5</accession>
    <name>A0A1C7NFD5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">A0J61_04138</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000195">
        <property type="protein sequence ID" value="OBZ87811.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="InParanoid" id="A0A1C7NFD5"/>
    <dbReference type="OrthoDB" id="1555531at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050335">
        <property type="entry name" value="ERT1_acuK_gluconeogen_tf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47659:SF4">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47659">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="4">
        <location>
            <begin position="45"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="351"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="458"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="372"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="459"/>
            <end position="479"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OBZ87811.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="479" mass="52977" checksum="B9069748FD03FC9C" modified="2016-11-30" version="1">MDYNGSLIETGTLPSLMYVDYTQQPSQPQLNPSKKRPNKIHVSAACANCKKAHLACDVSRPCNRCVATDKADTCHDIQHKKRGRPKMMRDANNNKIRPAAPIEISRSSQKTLSSSSPDLFILPSNEVMTILLSMDLCCARISDRSLEYLELYPQEFSHRSLYDFLVPGESQQTLSRLHRYLLDNAVQHQKTKLPTNLIRSSYEKFFSCTLESLLNIANGSLTIKQKLKFKHGSDNSRTEEMNCRFYLGGGFGADLIEAKDLEQLYIVCIXSPINPTGTSHPSSTAHINVPIGSHSLNSTLATSSSGDSLSTTIPHTMSDMIHLPPLIINNDSSPTLSSASPTVTHLAVSDEMAKPGVSNEEKNENQDEESSTQHQSKSPTSSSAKRITNDSNTIHLPLISSALVYENNKGKSLLERFKYNTQPQSQHFIHPNELYYMKTTSSRLSSEAIARTTYPYLSKASTNTTGSGPLASYNSSLNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NFJ5</accession>
    <name>A0A1C7NFJ5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Tyrosine-protein phosphatase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">iphP</name>
        <name evidence="1" type="ORF">A0J61_04623</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000230">
        <property type="protein sequence ID" value="OBZ87326.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NFJ5"/>
    <dbReference type="STRING" id="101091.A0A1C7NFJ5"/>
    <dbReference type="InParanoid" id="A0A1C7NFJ5"/>
    <dbReference type="OrthoDB" id="9988524at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004721">
        <property type="term" value="F:phosphoprotein phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.190.10">
        <property type="entry name" value="Protein tyrosine phosphatase superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029021">
        <property type="entry name" value="Prot-tyrosine_phosphatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026893">
        <property type="entry name" value="Tyr/Ser_Pase_IphP-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016130">
        <property type="entry name" value="Tyr_Pase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31126:SF1">
        <property type="entry name" value="TYROSINE SPECIFIC PROTEIN PHOSPHATASES DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31126">
        <property type="entry name" value="TYROSINE-PROTEIN PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13350">
        <property type="entry name" value="Y_phosphatase3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52799">
        <property type="entry name" value="(Phosphotyrosine protein) phosphatases II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00383">
        <property type="entry name" value="TYR_PHOSPHATASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ87326.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="319" mass="36425" checksum="DFF6A3DD625BCEEF" modified="2016-11-30" version="1">MAQLSDAYYNKVEGSFGVLNFRDLGVSSAENIENKKYIKEGLIFRSATLDNMRQEDVDAFIKAHRINTILDLRTGMEGREGLPIDKSFPTSALVNIDPKAIMKDDSKHKEPVALEEIDTTGKGSLVRRKYRIDFAGKNFQRYCVFASCSFRLKLYVIYLMLFCQRKRAAYIIGQEVLSPMGVNQMYKEFATYCKEEIREALMVFTDPSNYPIEIHCTQGKDRTGMVSAFVMAIAGVPQDVIVNDYAKTQKGLAPVYNEMLEEVRRSGLSEDFAQAPPQYMHDLLNFLTEKYGSIDNYLDNIGFGEEMRNRVRKIICVNH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NFM4</accession>
    <name>A0A1C7NFM4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Solute carrier family 35 member F6</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">SLC35F6_0</name>
        <name evidence="2" type="ORF">A0J61_04053</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000190">
        <property type="protein sequence ID" value="OBZ87902.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NFM4"/>
    <dbReference type="STRING" id="101091.A0A1C7NFM4"/>
    <dbReference type="InParanoid" id="A0A1C7NFM4"/>
    <dbReference type="OrthoDB" id="29773at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037185">
        <property type="entry name" value="EmrE-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13146">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13146:SF0">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 35 MEMBER F6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103481">
        <property type="entry name" value="Multidrug resistance efflux transporter EmrE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="47"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="106"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="163"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="189"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="228"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="265"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="321"/>
            <end position="340"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ87902.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="356" mass="39907" checksum="F559DF24762FC908" modified="2016-11-30" version="1">MSVLHTSFLTLGLLISGVCIPLILSFQDNQKIYLDKDQDEYYFFSQPLLQTSMIFLGEIVCILIIHIVNRSSMDQSMRETINSNGNNYSDYNEWVTPRTSTWSWSAIWFALPSACDLIATTLLNLGLIYTTPSIYQMMRSSIIGFSAIFSCLFLSRKFLRKEWVSIAFILLGTGIIVFSSIWHRDDANYLGPLLLVAAQLFVAGQFILEEYLMDRYHLDPVRAMGIEGIFGTLLLSVTLIITAFVGQGQFDVAQGIQDMIHHASLWQSALALTFMVAIFNFFGLTVSTSIGVPGRSIIDTLRTILTWAIAIHYSWDSFSWLELVGFIVLVLGVFIFNGVFSNLKSGSISETAPLLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NFT0</accession>
    <name>A0A1C7NFT0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">ribonuclease T2</fullName>
            <ecNumber evidence="2">4.6.1.19</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">RNRH_1</name>
        <name evidence="7" type="ORF">A0J61_03938</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the RNase T2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.6.1.19" evidence="2"/>
    <dbReference type="EMBL" id="LUGH01000181">
        <property type="protein sequence ID" value="OBZ88011.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NFT0"/>
    <dbReference type="STRING" id="101091.A0A1C7NFT0"/>
    <dbReference type="InParanoid" id="A0A1C7NFT0"/>
    <dbReference type="OrthoDB" id="435754at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033897">
        <property type="term" value="F:ribonuclease T2 activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006401">
        <property type="term" value="P:RNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01061">
        <property type="entry name" value="RNase_T2_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.730.10">
        <property type="entry name" value="Ribonuclease T2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033697">
        <property type="entry name" value="Ribonuclease_T2_eukaryotic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001568">
        <property type="entry name" value="RNase_T2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036430">
        <property type="entry name" value="RNase_T2-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018188">
        <property type="entry name" value="RNase_T2_His_AS_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033130">
        <property type="entry name" value="RNase_T2_His_AS_2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11240">
        <property type="entry name" value="RIBONUCLEASE T2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11240:SF22">
        <property type="entry name" value="RIBONUCLEASE T2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00445">
        <property type="entry name" value="Ribonuclease_T2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55895">
        <property type="entry name" value="Ribonuclease Rh-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00530">
        <property type="entry name" value="RNASE_T2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00531">
        <property type="entry name" value="RNASE_T2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013221243" description="ribonuclease T2" evidence="6">
        <location>
            <begin position="16"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="active site" evidence="4">
        <location>
            <position position="68"/>
        </location>
    </feature>
    <feature type="active site" evidence="4">
        <location>
            <position position="127"/>
        </location>
    </feature>
    <feature type="active site" evidence="4">
        <location>
            <position position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007469"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012571"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR633697-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU004328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OBZ88011.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="245" mass="27255" checksum="79A6B92D715DDC2E" modified="2016-11-30" version="1">MKLSLILPFLLSCTAQIIQLKNPSCSPNVLSCHWSGSVDACCSPKYGLVVLALQWAPGYGPNDQFTIHGLWPDTCSGGHGPFRGCDASRRSNAVGTIIRNNDPELYSRMRTFWPSNKDDNNWFWSHEWTKHGTCVSTLRPTCYGADYTKYQDVIDYFKKTLDLRDQFDLFGALNLNGVSPGRTYNVQTIRDAIKTAFGATAKLDCLHGALSEVSLNFYVKGTSDYVITDVLDQGNCRGAVSYPKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NFW2</accession>
    <name>A0A1C7NFW2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">ASX DEUBAD domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_04510</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000222">
        <property type="protein sequence ID" value="OBZ87446.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NFW2"/>
    <dbReference type="STRING" id="101091.A0A1C7NFW2"/>
    <dbReference type="InParanoid" id="A0A1C7NFW2"/>
    <dbReference type="OrthoDB" id="2289918at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028020">
        <property type="entry name" value="ASX_DEUBAD_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13919">
        <property type="entry name" value="ASXH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ASX DEUBAD" evidence="2">
        <location>
            <begin position="224"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="95"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="95"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="115"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="141"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="184"/>
            <end position="210"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ87446.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="346" mass="40094" checksum="FC76FD9C88BF7AB9" modified="2016-11-30" version="1">MSFTDLTDHSSDAPVGDKRKMTEIGQDENKKKKRYTVQDIFAFPISTEIKPKKVEARGRKKKTVEIKKVKKGKVETRGRKRRIVKTEEVLKEKQVKADTVQKEKPVKADIIQKPTKPETIQKSDKLAEPVRRSARAAKPIRFFDEETVVQKKEARGRKKKTIVIENDKEEQLKAQLNGRPKASLNERPKTPLNEQSKEEPIKQPKEEPIPKTKQNNEVVNGTPLDYFLTDKSSYLATADLRTLIPKWIKLLDPEERKELAQLLPSLDVSADDIHPSCYSLSNNFFWESVDRWQEDLAVGRFDRHALAKAKQKQQTEQDTTFKDENYEAYWGERLKRDKALKSSNQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NG16</accession>
    <name>A0A1C7NG16_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">A0J61_04041</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the krueppel C2H2-type zinc-finger protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000189">
        <property type="protein sequence ID" value="OBZ87910.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NG16"/>
    <dbReference type="STRING" id="101091.A0A1C7NG16"/>
    <dbReference type="InParanoid" id="A0A1C7NG16"/>
    <dbReference type="OrthoDB" id="654211at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000125">
        <property type="entry name" value="Putative zinc finger protein 143"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:002343">
        <property type="entry name" value="Zinc finger protein 33A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:001498">
        <property type="entry name" value="Zinc finger protein 404"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000624">
        <property type="entry name" value="zinc finger protein 697"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050329">
        <property type="entry name" value="GLI_C2H2-zinc-finger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19818:SF159">
        <property type="entry name" value="C2H2-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19818">
        <property type="entry name" value="ZINC FINGER PROTEIN ZIC AND GLI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <keyword evidence="5 8" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="9">
        <location>
            <begin position="18"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="9">
        <location>
            <begin position="49"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="9">
        <location>
            <begin position="79"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="9">
        <location>
            <begin position="109"/>
            <end position="132"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OBZ87910.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="203" mass="23986" checksum="B29D6449B7EBFD91" modified="2016-11-30" version="1">MDISFLLNTPSNEKDRPFVCYWDNACTKSFTRKSDLVRHKRIHTGERPYRCQWKDCNKQFIQRSALTVHLRTHTGERPHVCEFLNCQKSFSDSSSLARHRKTHSGKRPYICEKCDKCFTRNATLKRHQKQAHPIEIVSPFDATYPLTPPQESIQFVKKLNDGFSTFRSFKFEHYNITRNESSIVHLTPTACQNQGYEFRNFYV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NG23</accession>
    <name>A0A1C7NG23_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Ras-related protein YPT3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">YPT3</name>
        <name evidence="9" type="ORF">A0J61_04031</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Golgi apparatus membrane</location>
            <topology evidence="7">Lipid-anchor</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the small GTPase superfamily. Rab family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000188">
        <property type="protein sequence ID" value="OBZ87920.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NG23"/>
    <dbReference type="STRING" id="101091.A0A1C7NG23"/>
    <dbReference type="InParanoid" id="A0A1C7NG23"/>
    <dbReference type="OrthoDB" id="9989112at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016197">
        <property type="term" value="P:endosomal transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006887">
        <property type="term" value="P:exocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd01868">
        <property type="entry name" value="Rab11_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000067">
        <property type="entry name" value="ras-related protein RABA1f"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050209">
        <property type="entry name" value="Rab_GTPases_membrane_traffic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001806">
        <property type="entry name" value="Small_GTPase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47979">
        <property type="entry name" value="DRAB11-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00071">
        <property type="entry name" value="Ras"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00449">
        <property type="entry name" value="RASTRNSFRMNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00175">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00176">
        <property type="entry name" value="RAN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00173">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00174">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51419">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51421">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51420">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="5" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-0636">Prenylation</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="180"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="212"/>
            <end position="230"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023289"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00037794"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OBZ87920.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="230" mass="25753" checksum="7AAA0E94F8B7A3D0" modified="2016-11-30" version="1">MLSDDEYDYLFKLVLIGDSGVGKSNLLSRFTTNEFNLESKSTIGVEFATKNIEIEKRSIKAQIWDTSGQERYRAITGAYYRGAVGALVVYDITRRNSFQNVSHWLKELRDHADQNIVIMLVGNKVDLSETSRAVTTEEGAELAEKDGYLFMETSALDATNVDNAFEKVFTTIFENLPKTQTSADEKSAAGPTNGERVQLRPPSVRSMSRNSSMDENREYRKKDKASGGCC</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NGA2</accession>
    <name>A0A1C7NGA2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">sterol 22-desaturase</fullName>
            <ecNumber evidence="6">1.14.19.41</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">A0J61_03903</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 7">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.14.19.41" evidence="6"/>
    <dbReference type="EMBL" id="LUGH01000179">
        <property type="protein sequence ID" value="OBZ88048.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NGA2"/>
    <dbReference type="FunCoup" id="A0A1C7NGA2">
        <property type="interactions" value="424"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NGA2"/>
    <dbReference type="InParanoid" id="A0A1C7NGA2"/>
    <dbReference type="OrthoDB" id="1372046at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000249">
        <property type="term" value="F:C-22 sterol desaturase (NADPH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016125">
        <property type="term" value="P:sterol metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd11082">
        <property type="entry name" value="CYP61_CYP710"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.630.10:FF:000021">
        <property type="entry name" value="Cytochrome P450 61"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002403">
        <property type="entry name" value="Cyt_P450_E_grp-IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24286:SF228">
        <property type="entry name" value="C-22 STEROL DESATURASE ERG5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24286">
        <property type="entry name" value="CYTOCHROME P450 26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00465">
        <property type="entry name" value="EP450IV"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8" id="KW-0349">Heme</keyword>
    <keyword evidence="5 7 8" id="KW-0408">Iron</keyword>
    <keyword evidence="3 7 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="4 8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" description="axial binding residue" evidence="7">
        <location>
            <position position="460"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00039038"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR602403-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OBZ88048.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="517" mass="58596" checksum="A7C14B978C42BC03" modified="2016-11-30" version="1">MSSTSIFDPRSIESAKNAVASFMKAAFSQQKVSTTAVVCSAVVGLFAYEQYVYLKKKKNLPGPTFKIPIIGAFMDSLYPTFEGYMSKWKSGDLSCVSVFDRFVVIASTCDLSRKVLNAPAYAEPAVVDSMKYILCDDNWVFLSGKAHVDYRKGLNVLFTRKALGLYIPIQEKVYHKHFAEWLALDGLTEQYQLRFRELNMESSLRVFLGDYMSDEVAAKISVEYFNITAALELVNFPIPLPGTKVYKAIQSRKYIVKEFIECVKDSRIRMSNKGEIKSMMDAWINSMNEYEAECAANGKPAPRKFDDREISLTLLTFLFASQDATSSALTWAYQLLADHPEVLQKVYDEQVQVRKGQLDQPLTLELMEESTYLRQVVKEILRLRPPVLMVPYQTVREWPLTPGYVVPKGAMIIPSTYPALHDPVAYPNPDAFDPDRWGPEGTAEKYPKNFMVFGNGPHHCLGREYAIMHLMAVIAESALKLEWTHTRTDQSDDISIFATIYPQDGCIMSFRPKQVSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NGD7</accession>
    <name>A0A1C7NGD7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Galactose oxidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">GAOA_1</name>
        <name evidence="5" type="ORF">A0J61_05512</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000299">
        <property type="protein sequence ID" value="OBZ86434.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NGD7"/>
    <dbReference type="STRING" id="101091.A0A1C7NGD7"/>
    <dbReference type="InParanoid" id="A0A1C7NGD7"/>
    <dbReference type="OrthoDB" id="2019572at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02851">
        <property type="entry name" value="E_set_GO_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.80">
        <property type="entry name" value="Galactose oxidase/kelch, beta-propeller"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011043">
        <property type="entry name" value="Gal_Oxase/kelch_b-propeller"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037293">
        <property type="entry name" value="Gal_Oxidase_central_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009880">
        <property type="entry name" value="Glyoxal_oxidase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015202">
        <property type="entry name" value="GO-like_E_set"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32208:SF21">
        <property type="entry name" value="LOW QUALITY PROTEIN: ALDEHYDE OXIDASE GLOX-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32208">
        <property type="entry name" value="SECRETED PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07250">
        <property type="entry name" value="Glyoxal_oxid_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09118">
        <property type="entry name" value="GO-like_E_set"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="E set domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50965">
        <property type="entry name" value="Galactose oxidase, central domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008889683" evidence="2">
        <location>
            <begin position="24"/>
            <end position="559"/>
        </location>
    </feature>
    <feature type="domain" description="Glyoxal oxidase N-terminal" evidence="3">
        <location>
            <begin position="85"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="domain" description="Galactose oxidase-like Early set" evidence="4">
        <location>
            <begin position="447"/>
            <end position="548"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF07250"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF09118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OBZ86434.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="559" mass="62593" checksum="43ED247B099D595B" modified="2016-11-30" version="1">MKTLSFVSILSAISLILPHSVNGQISNNDSPFHWPDSQNIISPFSQTGKMEQIGRTGVAAMHAVLLNEKTILVIDKAEWNEAQFDSGQSAFSVQYDIETNEYRPLPLETNTFCSAGGFLANGTFISTGGGEKRGRDWKAEPGWQSIRHFNPCVDNTCLWSEFKTGKMTENRWYPTVEQLPEGDLFIIGGSTKGAAVNRAEINVPSYEFWPPRPEGEVPFPFLNETMPYNLYPFVFTLPDGNLFIFANKKAIIYDYNNQKIVKELPKIPGNPRTYPLTAGAIMLPLDPKNNYNVEILICGGSERMNRNAAADDTCGRINLGDEQPQWKMETFVHKRLMPDGLIMADGNLIWVNGCQRGWAGYNGRNHDPTFDPLIYTPDAPAGKRWTQNLANTDIARMYHSVALTLPDGRIWIAGSNNVDPPDVNAEYPTEFRVEYFSPPYLFKTATRPKISHVPRVVTYGQTFDILLNLDGLAISKEDASKIRVGLLRTGFSTHSMHMSQRYVFLEHEVSEDLQTLKVTAPPRAPIFPPGGGFLYVLYDGVPSVGTQIFVEHQLSDLKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NGM9</accession>
    <name>A0A1C7NGM9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Serine/threonine-protein kinase MAK</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">MAK</name>
        <name evidence="11" type="ORF">A0J61_03746</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the protein kinase superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000168">
        <property type="protein sequence ID" value="OBZ88195.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NGM9"/>
    <dbReference type="FunCoup" id="A0A1C7NGM9">
        <property type="interactions" value="434"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NGM9"/>
    <dbReference type="InParanoid" id="A0A1C7NGM9"/>
    <dbReference type="OrthoDB" id="2158884at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000624">
        <property type="entry name" value="Mitogen-activated protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050117">
        <property type="entry name" value="MAPK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24055">
        <property type="entry name" value="MITOGEN-ACTIVATED PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 11" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 8 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 9" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="10">
        <location>
            <begin position="12"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="41"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU000304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="OBZ88195.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="447" mass="51669" checksum="7C7F4CEE1E1679D6" modified="2016-11-30" version="1">MSIKQAPFLNTYELLEQIGNGSFAVVYKGKKRDSNELVAIKAMKKKISPSYQKEYKTMERLAPHPNIIQLFDVCHQTQSFLVMEYMNSGDLYQLLETRKQAGKRFHWKEIRSILTQVLAAFHHMHHIQGLFHRDIKPENLLIHQTQDAMIVKLADFGLATEIKSKRVAEDDYVSTRWYRAPEVLLKSTDYSFPIDLWALGTIFAELISLRPLFPGQSEEDQLIRISRLLGHPDLSYRKPSRRHRLYHHRSMPCLPEPLITQLGLGGFWREGALLAQKIGFEFPQTPPDPDALAQCLKPYCISTEAEDLLLKLLQYDPKKRITSTEALQHPFFLNDTVHSPTFQSLSPTVQLPKIPLSPINLEPSISSSCPLRPVDDSHVHTYFETPSSFAKTTSMPDFQLPQQQEPVLIPLQDAPKRLLKTPFQRLHRWTKRYISIDEQHSQNYHTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NGP3</accession>
    <name>A0A1C7NGP3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">A0J61_05388</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000289">
        <property type="protein sequence ID" value="OBZ86554.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NGP3"/>
    <dbReference type="STRING" id="101091.A0A1C7NGP3"/>
    <dbReference type="InParanoid" id="A0A1C7NGP3"/>
    <dbReference type="OrthoDB" id="2290221at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050815">
        <property type="entry name" value="TF_fung"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47338:SF5">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47338">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="38"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OBZ86554.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="604" mass="70486" checksum="FDF0B4CE1EB9C455" modified="2016-11-30" version="1">MLPCAACRKGRRKCVMTDGAKQCQRCERLQKLCLSGTLATEEQQVEFLETQIQQLNVAYDQLASLHAAVRSNNARMVQLIRNWKIKIEDGRFIIETNINNIHDLMSLASIPYLSPWSNLGTATEAKGSGLLFKFRSESKSNWTPFMIKLFTRSSQHASLTEPPLPKQQLFVKHCVDAFFSCHYFFRVLVHENSFRAKLDSLQDPLSDLTVLSICCYVCAIPCYHMSYDLTELRHRADTCYKKAKSMLLDQFDVHEKRLENAVSICLLAHYLHVTLRFSESRRLLDLAYQLCLDLEKDNKGHLKLFQTTHSSFPNENMDPEATDDPDQAVLVRVIYLIIYFRRLVNFFSSESSYYEPRLRLPKWKYLSDEKDQVKRTIRSQNWIISIFSHPFITCLWKEIHCVRIGRTCKLSFETIFRVEEVMMEWASIVPEEFRLSKDLNSYDLCSSAIESTIDVFKILLFTDFHMIQISIFSSLLQPSEEDLQIAQFVLHYAHEKSLQSCMHSLVASDALFFIIRVVHLLTLSSEEHISIQARELMKACYEQMHHLPFIHGLYLSTEESPMADILTLCKKEKPLNLDYYDTYTHPWFTLMYDMTRFTATHCYP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NGS8</accession>
    <name>A0A1C7NGS8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DNA helicase</fullName>
            <ecNumber evidence="3">3.6.4.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">fft2</name>
        <name evidence="14" type="ORF">A0J61_03991</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SNF2/RAD54 helicase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.12" evidence="3"/>
    <dbReference type="EMBL" id="LUGH01000185">
        <property type="protein sequence ID" value="OBZ87959.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NGS8"/>
    <dbReference type="FunCoup" id="A0A1C7NGS8">
        <property type="interactions" value="1108"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NGS8"/>
    <dbReference type="InParanoid" id="A0A1C7NGS8"/>
    <dbReference type="OrthoDB" id="448448at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000775">
        <property type="term" value="C:chromosome, centromeric region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000781">
        <property type="term" value="C:chromosome, telomeric region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031934">
        <property type="term" value="C:mating-type region heterochromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140658">
        <property type="term" value="F:ATP-dependent chromatin remodeler activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003682">
        <property type="term" value="F:chromatin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003678">
        <property type="term" value="F:DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042802">
        <property type="term" value="F:identical protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990918">
        <property type="term" value="P:double-strand break repair involved in meiotic recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000706">
        <property type="term" value="P:meiotic DNA double-strand break processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000122">
        <property type="term" value="P:negative regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033120">
        <property type="term" value="P:positive regulation of RNA splicing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000183">
        <property type="term" value="P:rDNA heterochromatin formation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030466">
        <property type="term" value="P:silent mating-type cassette heterochromatin formation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031509">
        <property type="term" value="P:subtelomeric heterochromatin formation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd18793">
        <property type="entry name" value="SF2_C_SNF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.10810:FF:000014">
        <property type="entry name" value="SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A containing DEAD/H box 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10810">
        <property type="entry name" value="Tandem AAA-ATPase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038718">
        <property type="entry name" value="SNF2-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049730">
        <property type="entry name" value="SNF2/RAD54-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000330">
        <property type="entry name" value="SNF2_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10799">
        <property type="entry name" value="SNF2/RAD54 HELICASE FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00176">
        <property type="entry name" value="SNF2-rel_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="9" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6 14" id="KW-0347">Helicase</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="12">
        <location>
            <begin position="426"/>
            <end position="596"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="13">
        <location>
            <begin position="803"/>
            <end position="962"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="55"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="93"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="142"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="242"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="56"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="96"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="163"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="251"/>
            <end position="261"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007025"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="OBZ87959.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="987" mass="113256" checksum="DB48623B56BEE34D" modified="2016-11-30" version="1">MPPPQGYSVSQANRTINSFFMPAKRTESTSGGPKIAVKNALKSNNLPTSNITRQLSSMSKALSSSSRSSSTDTLTRDLAKARIMDSNTAINKFNLSDDEEEEEVDDGDDDNNSVDINMKRVLRKRGPAKKMQLYFFSSEDEDEDDIVSTESSQLNRKRRIVLSDDEGSDDDKDTDDVSYIDKNEKINRSYNSANRRETIERLQKVCPNKSLEEIERVLIAKGSAVEALTALNQENRQILAGRNKRRRMIQDSDDDVDTEEEESRKTLSDAQKDRLVLKYFNNCTSKDLQDVTGCKPEYADKIINELRPFLDRDDLEEKLRKTKGTSPKYIDACSEMLDGYTAVDQIIEQIENVGSSLRKVLDYWEGQTGEEHDGLHMASIDQTLTSKTADPEYRKATRYCVTKQPACINPNLTLKDYQIVGLNWMLLLYGKGISGILADEMGLGKTAQVISFLGRLHEVGESGPHLIIVPSSTIENWIRELERFCPSLVVRLYHGSVDERAEQRMYLREERKQSAFQVIITTYQLAAGNPDDCNFLRKLRCESMILDEGHMVKNCQSSRYKKLMTIDTKFRLLLTGTPLQNNLQELVSLLTFIMPETFAECEDEIRSLFKIRNTAANSDDKKNQGKSNVSSVQMLSRERILRAKKMMTPFVLRRKKEDVLKDLPQKIQKIEYCAMTERQEELYSDIILKSKKTYQESVKEEPKKEKSAMSEQFESMRNIVIHLRKAVDHPLMFRKIYTDSMLREMAKKLKSDVKYWDSVEEYIYEDMTIMSDFELNSLCKEERTIKSYQLSNNEWMDSGKIDQLKILLPKFKKEGNKVLIFSQFTKMLDILELVMATLGVSFLRLDGETKVMERQNLIDEFNENQDIEVFLLSTKAGGFGINLTSANIVILYDLDFNPQNDKQAEDRAHRVGQTKDVTIYKLITKDSIEEHILKMANLKLSLDKNVSSKDGEETVDELEDTSNQKQSLQAMIKEAFVLADRRQARHV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NIS6</accession>
    <name>A0A1C7NIS6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_03230</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000135">
        <property type="protein sequence ID" value="OBZ88719.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="InParanoid" id="A0A1C7NIS6"/>
    <dbReference type="OrthoDB" id="2300795at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="21"/>
            <end position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ88719.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="261" mass="29492" checksum="EFE9FAB5B47E74F2" modified="2016-11-30" version="1">MIKGIVKVDLGISDDLAAYAKKKKEDKYGKLQRLRVSLKQELEDVLEDFREDNDLKKLKKKLMLISMDFEGAEERVVAVLLSLLNNLTVEKKQMNEMRIQSGLLXAVCNLFKLTMKHDAHGYNKILFETDALKNCRPDYVVEVGDDDLIINMVAEVKXENSXKNGVXIAPTSLSSSARFRQAICLMTKAGDLVVLSTFDDLGIIISQLNTMYNISLLYEKHCVVIEEEAKEWQLVDFEAVKELYNLPTTTLASTANISVIH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NIW6</accession>
    <name>A0A1C7NIW6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_03012</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000123">
        <property type="protein sequence ID" value="OBZ88930.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NIW6"/>
    <dbReference type="InParanoid" id="A0A1C7NIW6"/>
    <dbReference type="OrthoDB" id="10634977at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="204"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="211"/>
            <end position="227"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ88930.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="246" mass="27079" checksum="8CC5FA750D850124" modified="2016-11-30" version="1">MMASVAEELYAAHLKHIREAIAVVATPPPNMIIKQNSLVPALLSRVTANEIRCLWGSDCAPGHQVIVEVISTAVRDRLLAAPFFVDGVRLSFRLPVAKVSRYLLRQVPRGMTVDLLSRFFARFGDVMEVAPAPGEIPRSSDWTLSIVELNGYPLPLKIELWPSMAIDVFPVGACRRDHRPAACSSPTNIFTMESLTDNLDSLSISSAAPSSKKKKKNRRRRSKKNKLVKADPKLGVAENAPITDTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NJA5</accession>
    <name>A0A1C7NJA5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Calreticulin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="primary">CALR</name>
        <name evidence="16" type="ORF">A0J61_03066</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 11">Endoplasmic reticulum lumen</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11 14">Belongs to the calreticulin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000125">
        <property type="protein sequence ID" value="OBZ88889.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NJA5"/>
    <dbReference type="STRING" id="101091.A0A1C7NJA5"/>
    <dbReference type="InParanoid" id="A0A1C7NJA5"/>
    <dbReference type="OrthoDB" id="1938156at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005788">
        <property type="term" value="C:endoplasmic reticulum lumen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000324">
        <property type="term" value="C:fungal-type vacuole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036503">
        <property type="term" value="P:ERAD pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06503">
        <property type="entry name" value="ATP-synt_Fo_b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.10.250.10:FF:000002">
        <property type="entry name" value="Calreticulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.250.10">
        <property type="entry name" value="Calreticulin/calnexin, P domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001580">
        <property type="entry name" value="Calret/calnex"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018124">
        <property type="entry name" value="Calret/calnex_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009169">
        <property type="entry name" value="Calreticulin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009033">
        <property type="entry name" value="Calreticulin/calnexin_P_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11073:SF2">
        <property type="entry name" value="CALRETICULIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11073">
        <property type="entry name" value="CALRETICULIN AND CALNEXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00262">
        <property type="entry name" value="Calreticulin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002356">
        <property type="entry name" value="Calreticulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00626">
        <property type="entry name" value="CALRETICULIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63887">
        <property type="entry name" value="P-domain of calnexin/calreticulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00804">
        <property type="entry name" value="CALRETICULIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00805">
        <property type="entry name" value="CALRETICULIN_REPEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0106">Calcium</keyword>
    <keyword evidence="10 11 14" id="KW-0143">Chaperone</keyword>
    <keyword evidence="13" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="7 11 14" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="5" id="KW-0430">Lectin</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 14" id="KW-0732">Signal</keyword>
    <keyword evidence="8" id="KW-0862">Zinc</keyword>
    <feature type="signal peptide" evidence="14">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008810995" description="Calreticulin" evidence="14">
        <location>
            <begin position="19"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="229"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="366"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="15">
        <location>
            <begin position="366"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="15">
        <location>
            <begin position="394"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="109"/>
        </location>
        <ligand>
            <name>an alpha-D-glucoside</name>
            <dbReference type="ChEBI" id="CHEBI:22390"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="111"/>
        </location>
        <ligand>
            <name>an alpha-D-glucoside</name>
            <dbReference type="ChEBI" id="CHEBI:22390"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="128"/>
        </location>
        <ligand>
            <name>an alpha-D-glucoside</name>
            <dbReference type="ChEBI" id="CHEBI:22390"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="135"/>
        </location>
        <ligand>
            <name>an alpha-D-glucoside</name>
            <dbReference type="ChEBI" id="CHEBI:22390"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="316"/>
        </location>
        <ligand>
            <name>an alpha-D-glucoside</name>
            <dbReference type="ChEBI" id="CHEBI:22390"/>
        </ligand>
    </feature>
    <feature type="disulfide bond" evidence="13">
        <location>
            <begin position="105"/>
            <end position="137"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004319"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010983"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022734"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRNR" id="PIRNR002356"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR002356-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR002356-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU362126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="OBZ88889.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="419" mass="47569" checksum="144DB2BE0BF8EF48" modified="2016-11-30" version="1">MKIPTIAAILGLAAVASAEVFLHETFSDGEGWKERWTPSTYREDLGQLEVSSGKWSVNEAAQAGLRTTEDYRFYAVSSKIPKPFNNKDKNLVIQYDVKNEQDIDCGGSYLKIFNNELDQKTFNGDSQYNIMFGPDICGPKAMVHAIFNYNGTNHDLKKTVSAPKDTLTHTYTLTVKPDQTYAILVDGKEEASGSLLEDWDFLPPKKIKDPNASKPKDWVDEEMIDDVNDVKPEGYDDIPEFIPDQDAKKPEDWDDDMDGEWEPPSIANPDYKGPWSPKKIPNPLYKGEWEHPEIDNPEYKEDNEIYAFDFGHVGIDIWQVKSGTLFDNILITDDIEEAKKVREESKAAREDEEKALADYKEKLAAETKAKNEAEGILTEEKDSKVNVDEILAEQSEKAKEEEILEAIKEDEKRPAKDEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NJE8</accession>
    <name>A0A1C7NJE8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">CTP synthase</fullName>
            <ecNumber evidence="9">6.3.4.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">UTP--ammonia ligase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="primary">ura7_0</name>
        <name evidence="12" type="ORF">A0J61_03343</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8 9">
            <text>UTP + L-glutamine + ATP + H2O = CTP + L-glutamate + ADP + phosphate + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:26426"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:37563"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:46398"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.4.2"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 9">Pyrimidine metabolism; CTP biosynthesis via de novo pathway; CTP from UDP: step 2/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the CTP synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.4.2" evidence="9"/>
    <dbReference type="EMBL" id="LUGH01000142">
        <property type="protein sequence ID" value="OBZ88606.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NJE8"/>
    <dbReference type="FunCoup" id="A0A1C7NJE8">
        <property type="interactions" value="325"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NJE8"/>
    <dbReference type="InParanoid" id="A0A1C7NJE8"/>
    <dbReference type="OrthoDB" id="1739076at2759"/>
    <dbReference type="UniPathway" id="UPA00159">
        <property type="reaction ID" value="UER00277"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097268">
        <property type="term" value="C:cytoophidium"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003883">
        <property type="term" value="F:CTP synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042802">
        <property type="term" value="F:identical protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044210">
        <property type="term" value="P:'de novo' CTP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019856">
        <property type="term" value="P:pyrimidine nucleobase biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd03113">
        <property type="entry name" value="CTPS_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01746">
        <property type="entry name" value="GATase1_CTP_Synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000207">
        <property type="entry name" value="CTP synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.880:FF:000005">
        <property type="entry name" value="CTP synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01227">
        <property type="entry name" value="PyrG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004468">
        <property type="entry name" value="CTP_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017456">
        <property type="entry name" value="CTP_synthase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017926">
        <property type="entry name" value="GATASE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033828">
        <property type="entry name" value="GATase1_CTP_Synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003792">
        <property type="entry name" value="PRK05380.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00337">
        <property type="entry name" value="PyrG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11550">
        <property type="entry name" value="CTP SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11550:SF0">
        <property type="entry name" value="CTP SYNTHASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06418">
        <property type="entry name" value="CTP_synth_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00117">
        <property type="entry name" value="GATase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="Class I glutamine amidotransferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51273">
        <property type="entry name" value="GATASE_TYPE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 9" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="3 9" id="KW-0436">Ligase</keyword>
    <keyword evidence="4 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7 9" id="KW-0665">Pyrimidine biosynthesis</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CTP synthase N-terminal" evidence="11">
        <location>
            <begin position="3"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="domain" description="Glutamine amidotransferase" evidence="10">
        <location>
            <begin position="318"/>
            <end position="554"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00047781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU810713"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF06418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="OBZ88606.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="564" mass="62441" checksum="8B9941FEB083A4FE" modified="2016-11-30" version="1">MTKYIVVSGGVISGIGKGVIASSTGTLLKTLGLRVTAIKIDPYLNIDAGLMTPLDHGEVFVLNDGGEVDLDLGNYERFLDVELSKINNITTGKIYQEVIEKERKGDYLGKTVQVVPHVTDAIQNWVERVAAMPVDDSGEKPDVCIIELGGTVGDIESAPFVEAMRQFQFRVGHDNFCLIHVSLVPVVGSVGEQKTKPTQMSVRDLRGAGLSPDLIACRSSKPLDDSVASKISMFCHVAPEQVLAVHDVSSVYHVPILMRESGVIDFFRRRLNLDALKINEDCRVAGEHLWNEWTTLASSYTHLHETVTIAIVGKYTDLHDSYISVYKALEHASLAHQRKIKIRWVDASDLESETLKSNPLKYHESWKDVCSSDGILVPGGFGSRGIEGMIMAAKWAREHKVPYLGICLGMQIAVIEFARHVCGMADAHSAEMNPDTPTPVVVYMPEISKTHMGGTMRLGLRPTHFQKGTENSRVRKLYGGKSSVDERHRHRYEVNPELVNEIEAKGLQFVGKDETGQRMEIVELDDHPYFVGCQYHPEYLTRPLKPCPLFSGLVLAAIGKIDTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NJS9</accession>
    <name>A0A1C7NJS9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Transcription factor SOX-6</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">SOX6</name>
        <name evidence="5" type="ORF">A0J61_02695</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000105">
        <property type="protein sequence ID" value="OBZ89248.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NJS9"/>
    <dbReference type="STRING" id="101091.A0A1C7NJS9"/>
    <dbReference type="InParanoid" id="A0A1C7NJS9"/>
    <dbReference type="OrthoDB" id="2275950at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001228">
        <property type="term" value="F:DNA-binding transcription activator activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030154">
        <property type="term" value="P:cell differentiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.30.10">
        <property type="entry name" value="High mobility group box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009071">
        <property type="entry name" value="HMG_box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036910">
        <property type="entry name" value="HMG_box_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050140">
        <property type="entry name" value="SRY-related_HMG-box_TF-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10270:SF161">
        <property type="entry name" value="SEX-DETERMINING REGION Y PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10270">
        <property type="entry name" value="SOX TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00505">
        <property type="entry name" value="HMG_box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00398">
        <property type="entry name" value="HMG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47095">
        <property type="entry name" value="HMG-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50118">
        <property type="entry name" value="HMG_BOX_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0804">Transcription</keyword>
    <feature type="domain" description="HMG box" evidence="4">
        <location>
            <begin position="91"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="HMG box" evidence="3">
        <location>
            <begin position="91"/>
            <end position="159"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OBZ89248.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="285" mass="32918" checksum="F088EF9AC8A019B4" modified="2016-11-30" version="1">MKATKVEAITFSKDNKGSTILTVFPGAVSIQAKELINMVRENFNEIFIDGSTCILREEILKAIHDYPSDSRYTVSEKSVMSSSNPSKTHEPKRPTNAFIIYNNDHRKKIKMLFPEFNNSEVSKLLGAIWKSIGSEVKDTYIRKAIECRKIHKQKYPHFEYNLKRGLFAQKPSTISTNHSENWDDYFNWCLENVSTQSASGMIREDNLAGLEVAEANEQMEIHFNPDARLCIEKNSQESWEEVYNIISNLLPEEDSRNTFFDEQLWGSLDQITVFNETDSDFIRFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NK26</accession>
    <name>A0A1C7NK26_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Protein translation factor SUI1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">SUI1A</name>
        <name evidence="4" type="ORF">A0J61_02552</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SUI1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000097">
        <property type="protein sequence ID" value="OBZ89395.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NK26"/>
    <dbReference type="FunCoup" id="A0A1C7NK26">
        <property type="interactions" value="333"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NK26"/>
    <dbReference type="InParanoid" id="A0A1C7NK26"/>
    <dbReference type="OrthoDB" id="10248435at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11566">
        <property type="entry name" value="eIF1_SUI1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.780.10">
        <property type="entry name" value="SUI1-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001950">
        <property type="entry name" value="SUI1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036877">
        <property type="entry name" value="SUI1_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005874">
        <property type="entry name" value="SUI1_euk"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10388">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR SUI1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01253">
        <property type="entry name" value="SUI1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004499">
        <property type="entry name" value="SUI1_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55159">
        <property type="entry name" value="eIF1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50296">
        <property type="entry name" value="SUI1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SUI1" evidence="3">
        <location>
            <begin position="30"/>
            <end position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005422"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OBZ89395.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="112" mass="12799" checksum="0C26C98A0378947B" modified="2016-11-30" version="1">MSSIEELSVPFDPFADVEETTVQTTNTRNIHLRIQQRNGRKTVTTLQGLPKEYDAKKILKVFRKEFACSGKVVEHEEFGDILQLAGDQRLKIAEFLVNEHIATKTDIKIHGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NKD5</accession>
    <name>A0A1C7NKD5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="8">GTPase-activating protein BEM2/IPL2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">BEM2</name>
        <name evidence="8" type="ORF">A0J61_02511</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000095">
        <property type="protein sequence ID" value="OBZ89450.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NKD5"/>
    <dbReference type="InParanoid" id="A0A1C7NKD5"/>
    <dbReference type="OrthoDB" id="79452at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005085">
        <property type="term" value="F:guanyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007264">
        <property type="term" value="P:small GTPase-mediated signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.840.10">
        <property type="entry name" value="Ras guanine-nucleotide exchange factors catalytic domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.555.10">
        <property type="entry name" value="Rho GTPase activation protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.870.10">
        <property type="entry name" value="Son of sevenless (SoS) protein Chain: S domain 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041681">
        <property type="entry name" value="PH_9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001849">
        <property type="entry name" value="PH_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000651">
        <property type="entry name" value="Ras-like_Gua-exchang_fac_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023578">
        <property type="entry name" value="Ras_GEF_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001895">
        <property type="entry name" value="RASGEF_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036964">
        <property type="entry name" value="RASGEF_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050729">
        <property type="entry name" value="Rho-GAP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008936">
        <property type="entry name" value="Rho_GTPase_activation_prot"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000198">
        <property type="entry name" value="RhoGAP_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23176:SF133">
        <property type="entry name" value="GTPASE-ACTIVATING PROTEIN PAC-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23176">
        <property type="entry name" value="RHO/RAC/CDC GTPASE-ACTIVATING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15410">
        <property type="entry name" value="PH_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00617">
        <property type="entry name" value="RasGEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00618">
        <property type="entry name" value="RasGEF_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00620">
        <property type="entry name" value="RhoGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00233">
        <property type="entry name" value="PH"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00147">
        <property type="entry name" value="RasGEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00324">
        <property type="entry name" value="RhoGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48350">
        <property type="entry name" value="GTPase activation domain, GAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48366">
        <property type="entry name" value="Ras GEF"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50003">
        <property type="entry name" value="PH_DOMAIN"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50009">
        <property type="entry name" value="RASGEF_CAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50212">
        <property type="entry name" value="RASGEF_NTER"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50238">
        <property type="entry name" value="RHOGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0343">GTPase activation</keyword>
    <keyword evidence="2" id="KW-0344">Guanine-nucleotide releasing factor</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PH" evidence="4">
        <location>
            <begin position="150"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="domain" description="N-terminal Ras-GEF" evidence="6">
        <location>
            <begin position="361"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="domain" description="Ras-GEF" evidence="5">
        <location>
            <begin position="532"/>
            <end position="800"/>
        </location>
    </feature>
    <feature type="domain" description="N-terminal Ras-GEF" evidence="6">
        <location>
            <begin position="1032"/>
            <end position="1217"/>
        </location>
    </feature>
    <feature type="domain" description="PH" evidence="4">
        <location>
            <begin position="1799"/>
            <end position="1834"/>
        </location>
    </feature>
    <feature type="domain" description="Rho-GAP" evidence="7">
        <location>
            <begin position="1875"/>
            <end position="2066"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="41"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="874"/>
            <end position="917"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="43"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="54"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="874"/>
            <end position="890"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="891"/>
            <end position="900"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022468"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00168"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50009"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50238"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OBZ89450.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="2088" mass="237947" checksum="B57AB7AF84D368D8" modified="2016-11-30" version="1">MKTKKTSLSRPSNERSPNRNAFSFIKNRFFISSANSLDQHLISSPRPSVSTSSQLLNVETPNQRTREAITERAQIRNHSDTWLISGSLNEIDICKVDRTRPVSMVCVDLTSHSQSINELALQQSSVCRRNSTNTVPLKSGREQENRNSLIIVKEGYLYKKSDLKPFHRQSKSDRGWKPYRVVLRGHKLYLYKLATESLFRAHSPSSPTRHSSSSSAASIDIAVSEDKLYKSSNSTRPILSEFDEDTQRMFLEKSSDQLFGFVFVQLDPSSKKQIQHVYLILSEDTLHICNQLNNSWSSQATYPISSLTFKHNDQDGFVFSLLHEQATIGLFSIQRRDLGQAWISTLNSRMYDATQNCNRSHRLGYRCTTINALVHQLLKAEDETFLNTFLLTWPTFTTSACIFKELEACLMQQNQSNVVKLIKVWCQKSGLDVMGDIATSMMSILDTLDCKEAEDTRTLVLDVANENARKVRNNNTTFTFAITHSHAEEDQEISKEEENIQACQADGIKRDSINLSNLLITGLTPYLFLSIDHGSFAQQIYLFHSIKHAQFKSDLLNPLYFLPRPQIPIQMTSTLMFTSNSPHFLTKIIRTHILIDSQQEDMVKDHKKMRSRLLSHWIRVGEHLFNLGDMIGWSAVSLGVCSVGIVRLREAWKLVDRSLVHVVQDSWIPILVDHKLLNQDVGSGFETKQEILQSAKVLRLNGASLPFFGTIRQAADQYRRHATNTLESTLINFGEAEFLYKIVTTNLLDWQKKQTEQETVELLDILPVCPLQSYFEYLITDTMSVPHKHLLEWSMACEPKVFDQGCGRQNFKSNRLPFGLSNAIPPSATLLSFPKILESCTIFNSSYQDTLHLHTKPKKSKNTKSILDSDFFVSSQRDPSRSSAHTENNGSSSVTTSLSSPQRRPLPQRTHSFPPSAITDTDLIFNETSYSTHVRFGLLGHTSSHTWLDPKKCNKYHHTFSAKPSTDVRRNSKKAQEDILINARYGDIVFKVISENERKKGKIILRNLDHTTERTSKLKSNFSVVEIDRNTLIVTVKAGCLEQLVDLLLTGVSPYQDILIEQWHAKSLAEGRQQQKYTKIMMDEKEYASIFFVTYRTFCSSFHLVKTLHERFVDTKAKPWSPVETISKSALSESHAEQRNCTTSENSKLLNNQCGWKTLASTQLRILKVLLLWIERHPYDFADEVRTIQNFDIFLSDARAFFTNWSQSLRTKSKENEYVGTEEILKLIDNSEQCFRDLYTKFTAKIMSPIYDFDSVESDTKLSEEIENLYHQLKSGKQRYCTTLQIADNDSDSFSLSSHSFLPGAESLLDSFSPEVLLEQIDKNVRCLFNTVTMEEWLQLFSVIDAQANDLYAWLPAKKPSRTSRMEIALASVINAPLSYPTTYHILPEEVVISDIFTAIESARRSIVSLSAFSDDDLLLGFPATIQHLYCIHFIIRNWVVNDIANTKIDTKTRMMRIEKFLQMISFSNSKSEKLTMFPEGHAPGFVEYAISSALVSPEVRMFSKVWLDVAAKRSHANLSTLESLLRQTSASSSSFHNSCMYNLPSLKSESSTRSQKQNDWFVPSLGWIFECMLELCFHVPQIYQAGDNLINFDKSQCVSQFLQLVTSFQTIPIERPVAADGVRLALVVSPNLSRDTWKDLREVATQENKKQTTSGLAIRGSQRAIVFSKLVSEQLDKLKRHFKEKDKIDKEWLSYQQKLQKKQLEQAKQSDKQDRKTKMIFSAAMSASQAQQMQSHSMMPRINSFFKGLRPHSMISFPSLDLKNEFLLNPHSLTTKASTVVSLIHANTSVAITYTRRDFVFRIVTEDGGQFLLQAANREDMQSWVHHINNASKQGTAKRQSVLAAETAGINPFALSDNTQIRNHNPSRTSVFGVPLQILMKDNSIPLIVDKCIQEIEKRGLEEVGIYRIAGTGSIVSALKAAFNKDVTKVNLSAPIWADINVVADILKQFLRELPEPLATYRYYEEFVATAALEDHDERIYSLKLIIKKLPQANYTLLKRIVEHFVIVTDYEATNHMYATNLAIVFGPTLLQPTPSPIAFATTMSNIAHHQTIVKYLILNYHYLFDIDHDEIEPSAREEDQQILLKH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NKL6</accession>
    <name>A0A1C7NKL6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Transcription factor E2FC</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">E2FC</name>
        <name evidence="9" type="ORF">A0J61_02323</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the E2F/DP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000086">
        <property type="protein sequence ID" value="OBZ89615.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NKL6"/>
    <dbReference type="STRING" id="101091.A0A1C7NKL6"/>
    <dbReference type="InParanoid" id="A0A1C7NKL6"/>
    <dbReference type="OrthoDB" id="1743261at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090575">
        <property type="term" value="C:RNA polymerase II transcription regulator complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.10:FF:000008">
        <property type="entry name" value="E2F transcription factor 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.540">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015633">
        <property type="entry name" value="E2F"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037241">
        <property type="entry name" value="E2F-DP_heterodim"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003316">
        <property type="entry name" value="E2F_WHTH_DNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12081">
        <property type="entry name" value="TRANSCRIPTION FACTOR E2F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12081:SF18">
        <property type="entry name" value="TRANSCRIPTION FACTOR E2F2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02319">
        <property type="entry name" value="WHD_E2F_TDP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01372">
        <property type="entry name" value="E2F_TDP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144074">
        <property type="entry name" value="E2F-DP heterodimerization region"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3 5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0804">Transcription</keyword>
    <keyword evidence="2 5" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="E2F/DP family winged-helix DNA-binding" evidence="8">
        <location>
            <begin position="27"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="189"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="108"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="197"/>
            <end position="214"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010940"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003796"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM01372"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OBZ89615.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="246" mass="28559" checksum="675E79A94137EEEF" modified="2016-11-30" version="1">MCPIDNKRRKHDIDSKQSKVSNVQSCRYDSSLGLLTKKFIALLRSSTQGDLDLNRAAIQLKVQKRRIYDITNVLEGIHLIEKNSKNHVRWIGSHHPSNASPTSHSTTNNELEQRLELLKSYNQTLENEQRQLSTFKQQIDQEIESMIKTNSPYCYLTLDDIAKFEVIMAAQQEALVVVNAPYDTDIEVHHHHHHHQPQQNSHYSPYPTKKSSQTRTKCYIRVPENSNQSLQILSLRQSKQKDNEHQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NKN4</accession>
    <name>A0A1C7NKN4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Putative transporter C5D6.04</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">A0J61_02585</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000099">
        <property type="protein sequence ID" value="OBZ89369.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NKN4"/>
    <dbReference type="FunCoup" id="A0A1C7NKN4">
        <property type="interactions" value="36"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NKN4"/>
    <dbReference type="InParanoid" id="A0A1C7NKN4"/>
    <dbReference type="OrthoDB" id="191139at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004776">
        <property type="entry name" value="Mem_transp_PIN-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31794">
        <property type="entry name" value="AUXIN EFFLUX TRANSPORTER FAMILY PROTEIN (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31794:SF2">
        <property type="entry name" value="AUXIN EFFLUX TRANSPORTER FAMILY PROTEIN (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03547">
        <property type="entry name" value="Mem_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="6"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="42"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="68"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="102"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="143"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="269"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="339"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="376"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="411"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="186"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="190"/>
            <end position="203"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OBZ89369.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="438" mass="49113" checksum="2E47FE795D47940E" modified="2016-11-30" version="1">MWNLIIAAIQAIMQVMVIVFCGSILAKYGYFDMNKQKWLSKLNLIFFTPCLLFSNISSIISFEKLLAFWPIPCFYLIYAIMNYTSSQIITRLAGLTPAYRRFVLACVMFSNSNSLPIAIISSLSVSEAAHILFWKEDDTPETIAARGISYTLFFAIFGNLIRWSYGYQLLQKHDDDNSHLTIQGHDEEQTQPSSYQSFNQPVASSSSSSSSIEYLTTTGHISSRQMSSTTLADENTQLLNKNKQQQQQQQQGRLRSLARRIHSFMSPPLYAAFLALAVGLSPLKPILYDKQSFLYPSFTKAIELCGKAAVPLILTCLGAQLVDIAQSTHPASPQMKKPVALAIAIRMVLMPFLVVPLVVLFVVYGSHWSTMASDPVFITMMIVLGCTPTAINLVQITQVNNIFEEEMLRMLFWSYGVVCVPVCTFVVFLALNVVDRLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NKX2</accession>
    <name>A0A1C7NKX2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Putative eukaryotic translation initiation factor 2 subunit beta</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">tif212</name>
        <name evidence="6" type="ORF">A0J61_02168</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the eIF-2-beta/eIF-5 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000078">
        <property type="protein sequence ID" value="OBZ89777.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NKX2"/>
    <dbReference type="FunCoup" id="A0A1C7NKX2">
        <property type="interactions" value="630"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NKX2"/>
    <dbReference type="InParanoid" id="A0A1C7NKX2"/>
    <dbReference type="OrthoDB" id="10255414at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016282">
        <property type="term" value="C:eukaryotic 43S preinitiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005850">
        <property type="term" value="C:eukaryotic translation initiation factor 2 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043614">
        <property type="term" value="C:multi-eIF complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990856">
        <property type="term" value="F:methionyl-initiator methionine tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031369">
        <property type="term" value="F:translation initiation factor binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001731">
        <property type="term" value="P:formation of translation preinitiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.30.170:FF:000001">
        <property type="entry name" value="Eukaryotic translation initiation factor 2 subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.30.170">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045196">
        <property type="entry name" value="IF2/IF5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002735">
        <property type="entry name" value="Transl_init_fac_IF2/IF5_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016189">
        <property type="entry name" value="Transl_init_fac_IF2/IF5_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016190">
        <property type="entry name" value="Transl_init_fac_IF2/IF5_Zn-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23001">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23001:SF3">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 2 SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01873">
        <property type="entry name" value="eIF-5_eIF-2B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00653">
        <property type="entry name" value="eIF2B_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100966">
        <property type="entry name" value="Translation initiation factor 2 beta, aIF2beta, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75689">
        <property type="entry name" value="Zinc-binding domain of translation initiation factor 2 beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 6" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="3" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Translation initiation factor IF2/IF5" evidence="5">
        <location>
            <begin position="175"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="36"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="81"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="101"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="117"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="129"/>
            <end position="143"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010397"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00653"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OBZ89777.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="307" mass="35030" checksum="F1209E0810CD1C86" modified="2016-11-30" version="1">MSDNEKEPVQDQFEDEEVDFSKLKKKKKSKKKVDFEAEVEAEPVEEAPVDAEQNDDAEEDPEAMFADLKKKKKKKSKPVEEDAPEAEAAAENEEDLDFGALKKKKKKKKSMAQFEADLADENDDQDEAVEGKTNSKESGGEEAWLKSDRDYAYDELLDRVFNILRQNNPELAGEKKKYTIVPPSIHREGNKKTIFANVSEISKRLHRPADHVIQFLFAELGTTGSIDAAQRLIIKGRFQQKQIENVLRRYIVEYVTCKTCKSPNTIMTKDNRLYFVTCEHCGSTRSVSAIKTGFKAQTKEDRRALRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NL55</accession>
    <name>A0A1C7NL55_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 10">Carbonic anhydrase</fullName>
            <ecNumber evidence="2 10">4.2.1.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7 10">Carbonate dehydratase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="primary">can</name>
        <name evidence="11" type="ORF">A0J61_02230</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Reversible hydration of carbon dioxide.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8 10">
            <text>hydrogencarbonate + H(+) = CO2 + H2O</text>
            <dbReference type="Rhea" id="RHEA:10748"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:17544"/>
            <dbReference type="EC" id="4.2.1.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="9">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="9">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 10">Belongs to the beta-class carbonic anhydrase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.1" evidence="2 10"/>
    <dbReference type="EMBL" id="LUGH01000081">
        <property type="protein sequence ID" value="OBZ89728.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NL55"/>
    <dbReference type="FunCoup" id="A0A1C7NL55">
        <property type="interactions" value="317"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NL55"/>
    <dbReference type="InParanoid" id="A0A1C7NL55"/>
    <dbReference type="OrthoDB" id="10248475at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004089">
        <property type="term" value="F:carbonate dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015976">
        <property type="term" value="P:carbon utilization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00883">
        <property type="entry name" value="beta_CA_cladeA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.1050.10:FF:000001">
        <property type="entry name" value="Carbonic anhydrase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1050.10">
        <property type="entry name" value="Carbonic anhydrase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001765">
        <property type="entry name" value="Carbonic_anhydrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015892">
        <property type="entry name" value="Carbonic_anhydrase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036874">
        <property type="entry name" value="Carbonic_anhydrase_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF007756">
        <property type="entry name" value="PRK10437.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11002">
        <property type="entry name" value="CARBONIC ANHYDRASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11002:SF76">
        <property type="entry name" value="CARBONIC ANHYDRASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00484">
        <property type="entry name" value="Pro_CA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00947">
        <property type="entry name" value="Pro_CA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53056">
        <property type="entry name" value="beta-carbonic anhydrase, cab"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00704">
        <property type="entry name" value="PROK_CO2_ANHYDRASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00705">
        <property type="entry name" value="PROK_CO2_ANHYDRASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 10" id="KW-0456">Lyase</keyword>
    <keyword evidence="4 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 9 10" id="KW-0862">Zinc</keyword>
    <feature type="binding site" evidence="9">
        <location>
            <position position="71"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="73"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="127"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="130"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012925"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00014628"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00031969"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00048348"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR601765-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU003956"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="OBZ89728.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="239" mass="26776" checksum="BD875D6F3C286DB8" modified="2016-11-30" version="1">MSQPNKSLEFNEVFDKQASSALVNKFDPNDINLDGILESNRKWAKAVREQDPNFFSNIANKQTPKILWIGCSDSRVPANTVLQLNPGEVFVHRNIANVVSHSDLNCLSVLQYAVEVLKVEHIIVCGHYNCGGVGAAAGHGQFGLIDNWLRNIKDVYRLHEKELEAIKDEGLRLRKLIELNTINSAENVCHSTIVQNAWKRGQKLTIHALAYDIEDGCAKKLNWSASDKKACHSIFLSEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NLE2</accession>
    <name>A0A1C7NLE2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Cystinosin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">A0J61_02173</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000078">
        <property type="protein sequence ID" value="OBZ89790.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NLE2"/>
    <dbReference type="STRING" id="101091.A0A1C7NLE2"/>
    <dbReference type="InParanoid" id="A0A1C7NLE2"/>
    <dbReference type="OrthoDB" id="75720at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000324">
        <property type="term" value="C:fungal-type vacuole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005774">
        <property type="term" value="C:vacuolar membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015184">
        <property type="term" value="F:L-cystine transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.290">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005282">
        <property type="entry name" value="LC_transporter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006603">
        <property type="entry name" value="PQ-loop_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13131">
        <property type="entry name" value="CYSTINOSIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13131:SF5">
        <property type="entry name" value="CYSTINOSIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04193">
        <property type="entry name" value="PQ-loop"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00679">
        <property type="entry name" value="CTNS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="20"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="53"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="108"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="139"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="168"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="202"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="241"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="286"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="297"/>
            <end position="329"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OBZ89790.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="329" mass="37851" checksum="4DD91FF2DD6E2401" modified="2016-11-30" version="1">MATKSWDESSWTGWNLFSVFVGWSYVVVWSISFYPQAYLNWKRKSVRGLSIDFLFYNVLGFFCYSSAHSLVWCNQAYSLALYFDDEIRDEYHQRHPSSRNSLVRLNDVVFSVHGFLLSLFILLQTCVYRKQARQHISSFAAAFVWLTMLMSVLVLATIHYGGATSLDFLYFLSTVTLIVSFIKYLPQVWVNYKRQSTQGWSIQYISWDLAGGLLSIVQLLIDAYLDGDWTGIEGDNVKLGLGSIVVCYDALFMIQHYILYPKRISKHPIRDERKRLIEQCQPSRSDFKPIVEDDSNDASPSTAGSRLPINTRQAYGSTQHEFTPFSSSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NMD7</accession>
    <name>A0A1C7NMD7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_01918</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000067">
        <property type="protein sequence ID" value="OBZ90029.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NMD7"/>
    <dbReference type="InParanoid" id="A0A1C7NMD7"/>
    <dbReference type="OrthoDB" id="2284474at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="9"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="67"/>
            <end position="84"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ90029.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="303" mass="34769" checksum="B99951DEEA6EFC01" modified="2016-11-30" version="1">MDTVKPKRFSFSGFGSSLSRSLSFSSTKSKDEDPGLPSPPSEDELRKNKRTQKTKSLYIKSFRRSTGDTPKTTFDPSEANQPNSKEVKNAIRRSLSAVLYATPHASSENTNKLVPILVTSDLSDSVGGIMISEPGKSQEEEEKAIENKKKAVEYDNTLEIFSNKQNDAVTILWQGYGYTVQYDREALEVASEILQKEENVTDTPHYLESRFEKEVWTSYRGLIHPLHLFEPKQEEEVVDRGRWAGLGVSELRRYYDNYGSMMLKIRETRMIQQQRQYHCLTDVNKEWIIMSPTEAERKVDEMS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NMQ7</accession>
    <name>A0A1C7NMQ7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">60S ribosomal protein L8</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">rpl7a_3</name>
        <name evidence="7" type="ORF">A0J61_01806</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Component of the ribosome.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the eukaryotic ribosomal protein eL8 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000061">
        <property type="protein sequence ID" value="OBZ90159.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NMQ7"/>
    <dbReference type="FunCoup" id="A0A1C7NMQ7">
        <property type="interactions" value="613"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NMQ7"/>
    <dbReference type="InParanoid" id="A0A1C7NMQ7"/>
    <dbReference type="OrthoDB" id="2340007at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022625">
        <property type="term" value="C:cytosolic large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042254">
        <property type="term" value="P:ribosome biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050257">
        <property type="entry name" value="eL8/uL1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029064">
        <property type="entry name" value="Ribosomal_eL30-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004037">
        <property type="entry name" value="Ribosomal_eL8-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004038">
        <property type="entry name" value="Ribosomal_eL8/eL30/eS12/Gad45"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018492">
        <property type="entry name" value="Ribosomal_eL8/Nhp2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001921">
        <property type="entry name" value="Ribosomal_eL8_euk"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23105">
        <property type="entry name" value="RIBOSOMAL PROTEIN L7AE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01248">
        <property type="entry name" value="Ribosomal_L7Ae"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00881">
        <property type="entry name" value="L7ARS6FAMILY"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00882">
        <property type="entry name" value="RIBOSOMALL7A"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55315">
        <property type="entry name" value="L30e-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01082">
        <property type="entry name" value="RIBOSOMAL_L7AE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 7" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="204"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="277"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="domain" description="Ribosomal protein eL8/eL30/eS12/Gadd45" evidence="6">
        <location>
            <begin position="35"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007337"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU367042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OBZ90159.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="319" mass="35818" checksum="BCE99024119912BE" modified="2016-11-30" version="1" fragment="single">NTATQVFKLLHKYRPESKTEKRDRLRAAAAAKAEKKEVAKTDKPVVVKYGINHITALVEAKKAQLVVIADDVDPIEMVIWLPALCRKMGIPYCIVKGKARLGTLVHKKTATALALTEVSEADKAELATVVSAVNTNFTSKWEEVRRHWGGGIMGPKSNAKMAKRAAIAAKEIAARQDTRPVLALLESHRDQSVFLHDMIENKRLIATLVAAQASIFYPLFLLLNPQEHPDEKHQITIFESLMPSGLALSWAFCISFEDRINLIQALKPSLTLYLEHHLKYIVVITLLFEVIVIWMSFICSIREERSIQLPLDQKSDLPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NMU6</accession>
    <name>A0A1C7NMU6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="1">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">FRK1_0</name>
        <name evidence="13" type="ORF">A0J61_03367</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="1"/>
    <dbReference type="EMBL" id="LUGH01000143">
        <property type="protein sequence ID" value="OBZ88584.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NMU6"/>
    <dbReference type="FunCoup" id="A0A1C7NMU6">
        <property type="interactions" value="257"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NMU6"/>
    <dbReference type="InParanoid" id="A0A1C7NMU6"/>
    <dbReference type="OrthoDB" id="193931at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106310">
        <property type="term" value="F:protein serine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035556">
        <property type="term" value="P:intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000571">
        <property type="entry name" value="Maternal embryonic leucine zipper kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.310.80">
        <property type="entry name" value="Kinase associated domain 1, KA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028375">
        <property type="entry name" value="KA1/Ssp2_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001772">
        <property type="entry name" value="KA1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24346">
        <property type="entry name" value="MAP/MICROTUBULE AFFINITY-REGULATING KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24346:SF110">
        <property type="entry name" value="NON-SPECIFIC SERINE_THREONINE PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02149">
        <property type="entry name" value="KA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103243">
        <property type="entry name" value="KA1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50032">
        <property type="entry name" value="KA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 13" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="11">
        <location>
            <begin position="77"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="domain" description="KA1" evidence="12">
        <location>
            <begin position="753"/>
            <end position="803"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="359"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="485"/>
            <end position="528"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="583"/>
            <end position="617"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="719"/>
            <end position="742"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="359"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="487"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="499"/>
            <end position="521"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="586"/>
            <end position="606"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="607"/>
            <end position="617"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="719"/>
            <end position="737"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="106"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="OBZ88584.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="857" mass="97632" checksum="C56C4804EE8CB046" modified="2016-11-30" version="1">MATQVNQSNMTMATPVSPHQRAYSVMAIPSELEQHRHNKRHQHNNRTNHPDLSWHQEIYKKYGYEPKHKNPSYFGPYLLLQTLGEGEFAKVKAGVHVHTNQEVAIKLMRKDLIKHASLETKLEREISVLRSVHHPYIVQLFDVLTIKNYIGIVLQRAAGGELFDYILKHHYLQESEAKRLFAQLISGVHYMHQKHIVHRDLKLENLLLSKDRNILITDFGFANRFQMAQEDLMVTSCGSPCYAAPELVINDDSHYVGTAVDIWSCGVILFAMLCGYLPFDDDPSNPQGANINALYKYIVSTPLEIPSTMSVDATHLLRRMLVPDPAKRCTMDEIRSHPWLSDHWELLNMSIEELEQQMNHMPTSDPQPAVAEQNQNATTVTAESDVEPVSIDKEPVPELSSVVENEKTEQETDETPQFSEKAVIQPVCTTVQEDDEIPSLEVKQVSLDDEKHAEITQEQPKTIVEQEKLQPTSFLHDKFLKLQRRVSTNSHSSSSVSSRKQTPHVTLNDQIPDRSQSFQPQKTRRERTVSEYYTTTAQQAAARNGRKNSLKVVPSVSEQYVVSGSNTHKAKTKGQKLIDWFKRKPSQSTKFPRSNAANQNKLSTAESSDRFPLHERPISALPNPIRAMPIGKPLGSYAADFNDSRLRLHKGAVDQDALTSKAPNEVLQTITESLNMMGIDMKKSHDFKIKCVRPARQQSTYQRTRKISAVPFKLFFHPNTTQQQQQQQRQNKPSQRSHPVQEKKANVLYGEQGIDSGDEVQFTVELSKIENLPGLYVVDIRRTRGNIWAFKFLYHTLLDLLNLSGQSGMGYMAHRRVSDAEIKQQKQAEQQKNRISYMTTSSSGSSMMVFEEPIPHK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NN94</accession>
    <name>A0A1C7NN94_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 13">Transcription elongation factor SPT5</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="primary">spt5</name>
        <name evidence="18" type="ORF">A0J61_01346</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18 19">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11 13">The SPT4-SPT5 complex mediates both activation and inhibition of transcription elongation, and plays a role in pre-mRNA processing. This complex seems to be important for the stability of the RNA polymerase II elongation machinery on the chromatin template but not for the inherent ability of this machinery to translocate down the gene.</text>
    </comment>
    <comment type="subunit">
        <text evidence="12">Component of the SPT4-SPT5 complex. Interacts with RNA polymerase II.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 13">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 13">Belongs to the SPT5 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000041">
        <property type="protein sequence ID" value="OBZ90603.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NN94"/>
    <dbReference type="FunCoup" id="A0A1C7NN94">
        <property type="interactions" value="810"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NN94"/>
    <dbReference type="InParanoid" id="A0A1C7NN94"/>
    <dbReference type="OrthoDB" id="28901at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000785">
        <property type="term" value="C:chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032044">
        <property type="term" value="C:DSIF complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140463">
        <property type="term" value="F:chromatin-protein adaptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003711">
        <property type="term" value="F:transcription elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032784">
        <property type="term" value="P:regulation of DNA-templated transcription elongation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006368">
        <property type="term" value="P:transcription elongation by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd06081">
        <property type="entry name" value="KOW_Spt5_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd06082">
        <property type="entry name" value="KOW_Spt5_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd06083">
        <property type="entry name" value="KOW_Spt5_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd06084">
        <property type="entry name" value="KOW_Spt5_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd06085">
        <property type="entry name" value="KOW_Spt5_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd06086">
        <property type="entry name" value="KOW_Spt5_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd09888">
        <property type="entry name" value="NGN_Euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.30.30:FF:000018">
        <property type="entry name" value="Transcription elongation factor SPT5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.940:FF:000005">
        <property type="entry name" value="Transcription elongation factor SPT5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.30">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.940">
        <property type="entry name" value="NusG, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005824">
        <property type="entry name" value="KOW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041973">
        <property type="entry name" value="KOW_Spt5_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041975">
        <property type="entry name" value="KOW_Spt5_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041976">
        <property type="entry name" value="KOW_Spt5_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041977">
        <property type="entry name" value="KOW_Spt5_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041978">
        <property type="entry name" value="KOW_Spt5_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057934">
        <property type="entry name" value="KOW_Spt5_7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057936">
        <property type="entry name" value="KOWx_Spt5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005100">
        <property type="entry name" value="NGN-domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006645">
        <property type="entry name" value="NGN-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036735">
        <property type="entry name" value="NGN_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039385">
        <property type="entry name" value="NGN_Euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014722">
        <property type="entry name" value="Rib_uL2_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039659">
        <property type="entry name" value="SPT5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024945">
        <property type="entry name" value="Spt5_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022581">
        <property type="entry name" value="Spt5_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017071">
        <property type="entry name" value="TF_Spt5_eukaryote"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008991">
        <property type="entry name" value="Translation_prot_SH3-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11125">
        <property type="entry name" value="SUPPRESSOR OF TY 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11125:SF7">
        <property type="entry name" value="TRANSCRIPTION ELONGATION FACTOR SPT5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12815">
        <property type="entry name" value="CTD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00467">
        <property type="entry name" value="KOW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23042">
        <property type="entry name" value="KOW1_SPT5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23284">
        <property type="entry name" value="KOW2_Spt5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23291">
        <property type="entry name" value="KOW4_SPT5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23290">
        <property type="entry name" value="KOW5_SPT5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23287">
        <property type="entry name" value="KOW7_SPT5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23037">
        <property type="entry name" value="KOWx_SPT5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03439">
        <property type="entry name" value="Spt5-NGN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11942">
        <property type="entry name" value="Spt5_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036945">
        <property type="entry name" value="Spt5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01104">
        <property type="entry name" value="CTD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00739">
        <property type="entry name" value="KOW"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SMART" id="SM00738">
        <property type="entry name" value="NGN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50104">
        <property type="entry name" value="Translation proteins SH3-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0010">Activator</keyword>
    <keyword evidence="18" id="KW-0251">Elongation factor</keyword>
    <keyword evidence="10 13" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="18" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0678">Repressor</keyword>
    <keyword evidence="9 13" id="KW-0804">Transcription</keyword>
    <keyword evidence="7" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="NusG-like N-terminal" evidence="15">
        <location>
            <begin position="142"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="domain" description="KOW" evidence="16">
        <location>
            <begin position="236"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="domain" description="KOW" evidence="16">
        <location>
            <begin position="394"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="domain" description="KOW" evidence="16">
        <location>
            <begin position="446"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="domain" description="KOW" evidence="16">
        <location>
            <begin position="568"/>
            <end position="592"/>
        </location>
    </feature>
    <feature type="domain" description="KOW" evidence="16">
        <location>
            <begin position="678"/>
            <end position="705"/>
        </location>
    </feature>
    <feature type="domain" description="Spt5 C-terminal" evidence="17">
        <location>
            <begin position="765"/>
            <end position="918"/>
        </location>
    </feature>
    <feature type="domain" description="KOW" evidence="16">
        <location>
            <begin position="1046"/>
            <end position="1073"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="1"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="278"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="620"/>
            <end position="679"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="743"/>
            <end position="917"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="14">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="14">
        <location>
            <begin position="12"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="14">
        <location>
            <begin position="51"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="14">
        <location>
            <begin position="620"/>
            <end position="635"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="14">
        <location>
            <begin position="640"/>
            <end position="655"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="14">
        <location>
            <begin position="656"/>
            <end position="673"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="14">
        <location>
            <begin position="776"/>
            <end position="797"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="14">
        <location>
            <begin position="821"/>
            <end position="839"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="14">
        <location>
            <begin position="846"/>
            <end position="857"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="14">
        <location>
            <begin position="864"/>
            <end position="873"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006956"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00020181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00024691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00025870"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRNR" id="PIRNR036945"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="SMART" id="SM00738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="SMART" id="SM00739"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="SMART" id="SM01104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="OBZ90603.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="1104" mass="121443" checksum="62A450A935FFA068" modified="2016-11-30" version="1">MALKRSDRREDREDEVPYNEEEEEEDDDYDEDDEDVRPAKRRHNPFIDEMAIVDDDDDEEDDDEEYGKEDGFIEEENEELTTTKTTSRRHLELDRRRREMEGMDDEQVAAFYAEKYGGRSKPQSFKDTEEVPQQLLLPSVSDPNLWMVKCKPGKEKDVIFGLMKKYFDRQNGPYPIDTFSAFARETLKGYIYIEARRQAHVQETLTNIPNVYMSTLMLVPIKDMVDSITVQKKEVEIPLGGWVRVKRGTYAGDLAQVLEVSDSQDSARVKVVPRLDLESTHEDLQQQQSAGGKRKKGVRAPPKLFNPERLANRSLSSLQKKGPYWVYNGDHYRDGYLEKYMKIATLQVEDVNPTLDEIARFAGNGELNGEEGERSIDLTSLSSMAINNAQASTVFQNGDAVSVTEGDMIHSWGTVESVNDTQVTVSLEVEGLRKRVTLPARQLRKRFKEGDHVKVINGRFKDESGMVLNIQDNIVTLLSDASLKEVRVFAKDLREAAEVMFGKTVIGNYELHDLVQLDFYTVGVIVKVNRDSFQVLTQNGEMRTVQPHQITNKRDSNKAVATDANGNSIRSGDTVMEVGDKRTCSILHLYRHLAFLHSREHSENFGVWVTNTRSIVSATTRSRSLAQPKLQNPPYNNGYGRDDRGANGHGFDGRGGRGGARGGRGGAYGGRGGRGGRDNLVSKTVRISQGPHKGYIGIVKEATDTQARVELHTNSKVLNVDKSHLMILDAQGNPVGQAAPDRFDSPANNGGFARPMATPSRYGEGAMTPMHGAASGSRTPAWNASGSKTPAWNSGARTPNPYANDGGRTPAWDSGSKTPMWSHESSSSAWSSSYDNHASSNKHHSSSASQSHYGSSSEVAKTPGYSSMSNSSHRYPDVDSAPTPGASWTAPTPAASYEPRAPTPAVNFAQTPYDAPTPYDAGPSLNAGIIPPTPAAMMSAPTPGNYIPTTPGNFVPTTPATGIPQTPFMPSGGDYGHVEDQGDQGEDNWPIEEIEVVVKKNYGEAQKGQFAKIVTVNRNGRKCLISLLDASQAKVDVPFDSIEPVRPSKKDSVKIILGEHRGELGSLIGVDSHDGIVRLKGDGSGFKILSMNSVAKYTGTDNVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NPE1</accession>
    <name>A0A1C7NPE1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_02839</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000113">
        <property type="protein sequence ID" value="OBZ89114.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NPE1"/>
    <dbReference type="STRING" id="101091.A0A1C7NPE1"/>
    <dbReference type="InParanoid" id="A0A1C7NPE1"/>
    <dbReference type="OrthoDB" id="3363286at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ89114.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="120" mass="13590" checksum="1BB4AE3314D9E84E" modified="2016-11-30" version="1">MSKITVTELMQRWSKQAPKRAEKLSKCQISEMIKTTPNSLEARLAVNPYAAMLASPLRKCGFHSRIFPSSLLLRFGLAWHPETNRNWAYPTTDSKSENEGFGYYIQLKKGVVEAIQKGGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NPT7</accession>
    <name>A0A1C7NPT7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_00932</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000025">
        <property type="protein sequence ID" value="OBZ91000.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NPT7"/>
    <dbReference type="InParanoid" id="A0A1C7NPT7"/>
    <dbReference type="OrthoDB" id="2287173at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="47"/>
            <end position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ91000.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="298" mass="33446" checksum="4FC53BE06FA693B1" modified="2016-11-30" version="1">MTEKSFGNIILRARPDTSSSYCDDFQTPLPIKPKKQETEPSSPPSLPSTSSSAGTSTARFKTPTSLKSRKVQAGIDKPDEIRVIRDQEQTKSLSSSVVCKTCEVRHARSSSSQRRLQEPNKREKFKYFISTSVIKTNLNNVCQSEEFIKKLQDIVAHINQLVYAGAMFVASIGEMLHKKLEIALENLEESPSFGLRITKAEIFGQSSHRWQSIILSVINTNNLFVKFEKLENCHQKDALPAVEASIQEIQTKISQEKISPLKYIDTHGTPFVSLLPLHGCTPKHIRIKSNHSGRLPDQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NPX8</accession>
    <name>A0A1C7NPX8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="14">Peptidyl-prolyl cis-trans isomerase-like 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">cyp14</name>
        <name evidence="14" type="ORF">A0J61_02636</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">May catalyze the cis-trans isomerization of proline imidic peptide bonds in oligopeptides thereby assisting the folding of proteins. May also function as a chaperone, playing a role in intracellular transport of proteins. May also have a protein ubiquitin ligase activity acting as an E3 ubiquitin protein ligase or as a ubiquitin-ubiquitin ligase promoting elongation of ubiquitin chains on proteins.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.</text>
            <dbReference type="EC" id="2.3.2.27"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)</text>
            <dbReference type="Rhea" id="RHEA:16237"/>
            <dbReference type="Rhea" id="RHEA-COMP:10747"/>
            <dbReference type="Rhea" id="RHEA-COMP:10748"/>
            <dbReference type="ChEBI" id="CHEBI:83833"/>
            <dbReference type="ChEBI" id="CHEBI:83834"/>
            <dbReference type="EC" id="5.2.1.8"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the cyclophilin-type PPIase family. PPIL2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000102">
        <property type="protein sequence ID" value="OBZ89304.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NPX8"/>
    <dbReference type="FunCoup" id="A0A1C7NPX8">
        <property type="interactions" value="636"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NPX8"/>
    <dbReference type="InParanoid" id="A0A1C7NPX8"/>
    <dbReference type="OrthoDB" id="407558at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071013">
        <property type="term" value="C:catalytic step 2 spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000209">
        <property type="term" value="P:protein polyubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01923">
        <property type="entry name" value="cyclophilin_RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd16663">
        <property type="entry name" value="RING-Ubox_PPIL2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.40.10:FF:000079">
        <property type="entry name" value="Peptidyl-prolyl cis-trans isomerase 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.100.10:FF:000014">
        <property type="entry name" value="Peptidyl-prolyl cis-trans isomerase cyp65"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.100.10">
        <property type="entry name" value="Cyclophilin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029000">
        <property type="entry name" value="Cyclophilin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020892">
        <property type="entry name" value="Cyclophilin-type_PPIase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002130">
        <property type="entry name" value="Cyclophilin-type_PPIase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044666">
        <property type="entry name" value="Cyclophilin_A-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026951">
        <property type="entry name" value="PPIL2_U-box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003613">
        <property type="entry name" value="Ubox_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45625">
        <property type="entry name" value="PEPTIDYL-PROLYL CIS-TRANS ISOMERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45625:SF1">
        <property type="entry name" value="RING-TYPE E3 UBIQUITIN-PROTEIN LIGASE PPIL2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00160">
        <property type="entry name" value="Pro_isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04564">
        <property type="entry name" value="U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00153">
        <property type="entry name" value="CSAPPISMRASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00504">
        <property type="entry name" value="Ubox"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50891">
        <property type="entry name" value="Cyclophilin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00170">
        <property type="entry name" value="CSA_PPIASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50072">
        <property type="entry name" value="CSA_PPIASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51698">
        <property type="entry name" value="U_BOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 14" id="KW-0413">Isomerase</keyword>
    <keyword evidence="10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0697">Rotamase</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <keyword evidence="7" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="U-box" evidence="13">
        <location>
            <begin position="38"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="domain" description="PPIase cyclophilin-type" evidence="12">
        <location>
            <begin position="293"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="213"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="457"/>
            <end position="532"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="457"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="517"/>
            <end position="532"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00000971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00003697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00007930"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51698"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="OBZ89304.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="532" mass="60815" checksum="6F31D2022DFD4651" modified="2016-11-30" version="1">MGKWTDKLYITHSEWSGEVGQHSASAGITGHKSSSGFKRLPFYCCSLSLQPFEHPVCTPDGTIFDLVHIIPYIKKYGTNPVTGEKLETKQLIKLNFHKNDKDEYHCPVTFKVFSDHTAIAAIKTTGNVFAFDTIEKLNIKPKHWQDLLTDEPFSRKDIIMLQDPHNIEKKDRTQFDYVKSNKKVVNAAEEREKRKPENNINIAGMGNIKKVYDQLSQKKKSDEEEEEQPVPTSFHQKKANLPYNAAHYTTGAAAESFTSTAMNTYTQATRALIDEDEFMYKKIKSKAYARIITNYGNINVELFSDRVPRTCHNFVQLAKTGYYNNVIFHRNIKHFMIQGGDPTGTGRGGQSIWKRDFPDEIKTTLKHDARGVLSMANKGKDTNSSQFFITYGPAPQLDGQHTVFGKVVGGMDVLAKLEKVPVDDKDRPEREIKMKQVQVFVDPFEVYQTRLNNKLTHEANKEAEDEEAKRKREKEDKMGWFGPSVTESHVGVGKYLQQEKKREAVSEEEINSKRLKTTQQTKSKTYGNFDNF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NQQ3</accession>
    <name>A0A1C7NQQ3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Ketimine reductase mu-crystallin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">CRYM</name>
        <name evidence="2" type="ORF">A0J61_01210</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ornithine cyclodeaminase/mu-crystallin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000035">
        <property type="protein sequence ID" value="OBZ90746.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NQQ3"/>
    <dbReference type="FunCoup" id="A0A1C7NQQ3">
        <property type="interactions" value="382"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NQQ3"/>
    <dbReference type="InParanoid" id="A0A1C7NQQ3"/>
    <dbReference type="OrthoDB" id="41492at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1780.10">
        <property type="entry name" value="ornithine cyclodeaminase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003462">
        <property type="entry name" value="ODC_Mu_crystall"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023401">
        <property type="entry name" value="ODC_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13812">
        <property type="entry name" value="KETIMINE REDUCTASE MU-CRYSTALLIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13812:SF19">
        <property type="entry name" value="KETIMINE REDUCTASE MU-CRYSTALLIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02423">
        <property type="entry name" value="OCD_Mu_crystall"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001439">
        <property type="entry name" value="CryM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008903"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ90746.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="324" mass="35210" checksum="7A3BBE65AD1F4E9F" modified="2016-11-30" version="1">MVGQLRVLSETDIKCLLTQGGTKLALEIIDLMAKTFNKYSSNSTDIQSPQRISVSTDLHKVLFMPSRLETTTSIKIVSVPSDDRSSGLPATILVLNESSGSVEAIMNAVALTAIRTAAGSGVATDYYANPDSRNLVVFGAGAQGRSHVDMMIAIRPTIQQVAIWNRGQARRDRLIEELKRDYPDRLFVSANEALESYVREADIICTCTNATEPVLFGKWLKPGVHLNCVGSYQLHMHEVDAETVKRAELIVVDSTSACAHEAGELVLSSQPEAWAELGQVVLDQKDRQKITLFKSVGISVQDSAIAGLILQQAKNQGLGLEAPF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NR52</accession>
    <name>A0A1C7NR52_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">DIS3-like exonuclease 1</fullName>
            <ecNumber evidence="6">3.1.13.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="17">Ribosomal RNA-processing protein 44</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="20" type="primary">Dis3l</name>
        <name evidence="20" type="ORF">A0J61_00396</name>
    </gene>
    <organism evidence="20 21">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="20 21" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="20 21">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Exonucleolytic cleavage in the 3'- to 5'-direction to yield nucleoside 5'-phosphates.</text>
            <dbReference type="EC" id="3.1.13.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="3">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5 18">Belongs to the RNR ribonuclease family.</text>
    </comment>
    <comment type="caution">
        <text evidence="20">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.13.1" evidence="6"/>
    <dbReference type="EMBL" id="LUGH01000008">
        <property type="protein sequence ID" value="OBZ91583.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NR52"/>
    <dbReference type="STRING" id="101091.A0A1C7NR52"/>
    <dbReference type="InParanoid" id="A0A1C7NR52"/>
    <dbReference type="OrthoDB" id="372421at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000177">
        <property type="term" value="C:cytoplasmic exosome (RNase complex)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000176">
        <property type="term" value="C:nuclear exosome (RNase complex)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008859">
        <property type="term" value="F:exoribonuclease II activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000956">
        <property type="term" value="P:nuclear-transcribed mRNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016075">
        <property type="term" value="P:rRNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.700:FF:000001">
        <property type="entry name" value="Exosome complex exonuclease exoribonuclease (Rrp44)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.690">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.700">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041505">
        <property type="entry name" value="Dis3_CSD2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001900">
        <property type="entry name" value="RNase_II/R"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022966">
        <property type="entry name" value="RNase_II/R_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050180">
        <property type="entry name" value="RNR_Ribonuclease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033771">
        <property type="entry name" value="Rrp44_CSD1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23355:SF30">
        <property type="entry name" value="DIS3-LIKE EXONUCLEASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23355">
        <property type="entry name" value="RIBONUCLEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17849">
        <property type="entry name" value="OB_Dis3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00773">
        <property type="entry name" value="RNB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17216">
        <property type="entry name" value="Rrp44_CSD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00955">
        <property type="entry name" value="RNB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01175">
        <property type="entry name" value="RIBONUCLEASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="13 20" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="12" id="KW-0271">Exosome</keyword>
    <keyword evidence="11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="14" id="KW-0460">Magnesium</keyword>
    <keyword evidence="10" id="KW-0540">Nuclease</keyword>
    <keyword evidence="16" id="KW-0539">Nucleus</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="15" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="9" id="KW-0698">rRNA processing</keyword>
    <feature type="domain" description="RNB" evidence="19">
        <location>
            <begin position="293"/>
            <end position="634"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00005785"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00012163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00016366"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00077930"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="RuleBase" id="RU003901"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="SMART" id="SM00955"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="OBZ91583.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="865" mass="97912" checksum="EF46CCC59394B672" modified="2016-11-30" version="1">MTMKQYLDTYWKESHLLQNLVQVLAEVVLDETDDGRIRIASRQSNGEKGNSTAVAGYKEYKPMDELEAGIKSGRYLSGTLRCRKDSRDQAYISYQGKDILVVGNENRNRAVHGDSVVVELFSEKNWSMVSSEIAFDSSNADDEFEEDRFMSSTLSDQPTGRVVGILNRNWRSYVATLQEDSLETGGSIHLAIPLDPVIPKIRIRYHDVKLIENQRIVVRIDNWPISSQYPNGHFVRSLGPIHQLDTEISAILVEHAISVSQATQGFSQASLNEMPIDSSEQPWRTEKDEIKQRRDLRDLTVFSIDPPNCQDIDDALSIKDLENGNLELGVHIADVSYFVKENYMTDLEARSRGTTVYLADRRFDMLPSVLSERVCSLRHQVDRYAVSVIWTMDKDYNVIDTWFGRTVIKSSCEMEYEQAQQLLDGESVATGLDPSLCKKLKPKVIRLAEVLRVIRDRRLAKGALELEGSEIKFKITDQKKITDIIPKASMEIHGLVAEAMILANASVGRRIYDGFKDSALLRHHPSPSSQQFDRLVKAAESKGFSVDFSSNKALADSLKGITEGCKDDPEIAKLIKVMATIAMNEASYISSGHHAVNEYYHYGLALEFYTHFTSPIRRYADVVAHRQLLMCVGDPTAMKDVEERGSMMSKARTIADICENLNIKSRESKFAQRDSTELFQSLYVLQNSSEENPLIETGIISEIRSNGFYVFVPRLGLKGPVYLKEKDGKPHIPLSLISGTDAGNESIPNCQVEVNMPTHIKVTSADLPHPIEFNLFHHVRVSLKLRQSHAHRHLVYMTLIDFDLVETAKRPTMDRLSNTQMMQSIEAKEQEKVIKKPSSKKKKQTMYSVLEKFRKMSIIQTTANE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NR80</accession>
    <name>A0A1C7NR80_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Cilia-and flagella-associated protein 20</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">CFAP20</name>
        <name evidence="3" type="ORF">A0J61_02184</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000079">
        <property type="protein sequence ID" value="OBZ89754.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NR80"/>
    <dbReference type="STRING" id="101091.A0A1C7NR80"/>
    <dbReference type="InParanoid" id="A0A1C7NR80"/>
    <dbReference type="OrthoDB" id="7486196at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040441">
        <property type="entry name" value="CFA20/CFAP20DC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007714">
        <property type="entry name" value="CFA20_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12458">
        <property type="entry name" value="ORF PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05018">
        <property type="entry name" value="CFA20_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0966">Cell projection</keyword>
    <keyword evidence="3" id="KW-0969">Cilium</keyword>
    <keyword evidence="3" id="KW-0282">Flagellum</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CFA20" evidence="2">
        <location>
            <begin position="29"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF05018"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ89754.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="207" mass="24220" checksum="764DF89E607AF202" modified="2016-11-30" version="1">MCNSSTDPLQLWSSHLPENDTISNEEEHEQEVSYIKRVADDLISSTVFELSSPNLSNTFITCPQSHISLGIKLPYLVLVVKNMNRFFSFEVEVLDDENQKRRLRASNYQVTTRVKPYMLTMPMRLDQGWNQIVLNLSDYVKKGYGTNYLETSRVTIHANCRIRRVYFTDRLYQEDELPAEFKLFLPVKYMFLFSNMFCISHSSSTLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NRH5</accession>
    <name>A0A1C7NRH5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">A0J61_00200</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000004">
        <property type="protein sequence ID" value="OBZ91722.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NRH5"/>
    <dbReference type="InParanoid" id="A0A1C7NRH5"/>
    <dbReference type="OrthoDB" id="2290950at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008889848" evidence="3">
        <location>
            <begin position="22"/>
            <end position="500"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="137"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="89"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="197"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="111"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="121"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="202"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="223"/>
            <end position="237"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OBZ91722.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="500" mass="55184" checksum="92B24E162BA02C88" modified="2016-11-30" version="1">MQLSRTLSFLLLILIFHHVQTAAPAKRVTDEEVQCNENDASCQSNIRIQPTISPEIPKDELAFKTLISAASYETISNFHEAKVAHPPHQLGLPPLVENQPTNLPGFDLPDDTSSGIEQNPSSSEETVSSGLSRVETAVLSTCGVLVIAGIAVGIFVWRNTARNRQRHTDSDLEYEYEDEQDAANRDPVRRNLIRLNPVYSVSKEQPSSVHTFQEQGSQRDRNVSPTHEQQSKLSTELSRSESQTTSQSLILTSHHLRNSLYGPMFGGAPSIEPNSQSLTSSPQAIDIVQDPSTLTYPLQKFLKSSVSATHIPLAWASPSDSVGNSPNGISNNFNNEYTCDNIQEALHHNNDQTRKSMEQPSKSAHSLGHQLVNLFNKTSNITQNTKPLTKPKHPIVKLSNDNQLAIQVYTNKPISTTVTALGFFSPLDLPEDQYVPMRDAIGLPLVSRAEVMADPIRRLGKDEIALWEEGKRKKAIEVSKQRESTLVSPATLAAPDHCSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NRU7</accession>
    <name>A0A1C7NRU7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Putative tRNA/rRNA methyltransferase YsgA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">ysgA</name>
        <name evidence="4" type="ORF">A0J61_00069</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000002">
        <property type="protein sequence ID" value="OBZ91851.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NRU7"/>
    <dbReference type="STRING" id="101091.A0A1C7NRU7"/>
    <dbReference type="InParanoid" id="A0A1C7NRU7"/>
    <dbReference type="OrthoDB" id="270651at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008173">
        <property type="term" value="F:RNA methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006396">
        <property type="term" value="P:RNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd18095">
        <property type="entry name" value="SpoU-like_rRNA-MTase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1280.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029028">
        <property type="entry name" value="Alpha/beta_knot_MTases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029064">
        <property type="entry name" value="Ribosomal_eL30-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051259">
        <property type="entry name" value="rRNA_Methyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001537">
        <property type="entry name" value="SpoU_MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029026">
        <property type="entry name" value="tRNA_m1G_MTases_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43191">
        <property type="entry name" value="RRNA METHYLTRANSFERASE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43191:SF2">
        <property type="entry name" value="RRNA METHYLTRANSFERASE 3, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00588">
        <property type="entry name" value="SpoU_methylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75217">
        <property type="entry name" value="alpha/beta knot"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55315">
        <property type="entry name" value="L30e-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 4" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="tRNA/rRNA methyltransferase SpoU type" evidence="3">
        <location>
            <begin position="129"/>
            <end position="291"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00588"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OBZ91851.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="299" mass="33680" checksum="9278E517EC276E3D" modified="2016-11-30" version="1">MSKLFKEITSQHNVVAKHWIALREKKQYRLDHKSVLVQGAKTIRELHKQGCKITSLAITTSRKDPEMKQPGLSVFQDPSLLPAEKYYLADVNVVRRALGTSSKPAKHDVFAEIPIPEKTEQEVFKQDRLLVFDKITDPGNLGTLVRTAKALGWHAGVNASGTCDLYNDKTVRASRGLTVVWPHVAYPNMRIILNHLREQNYTPLVADMLPKDTKSSDLWSPEYNTLEPGKGVWFWNFQNGPFKEVPKRVALILSSEHHGVGELLDKEIKVSLPMYPGVESLNVANAGSIIMSELNRSMF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-06-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NUU5</accession>
    <name>A0A1C7NUU5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_00662</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000016">
        <property type="protein sequence ID" value="OBZ91264.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="InParanoid" id="A0A1C7NUU5"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ91264.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="9" mass="1174" checksum="930946C403240325" modified="2016-11-30" version="1">MSKRKRQIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NV47</accession>
    <name>A0A1C7NV47_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Glycerol 2-dehydrogenase (NADP(+))</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">GCY1</name>
        <name evidence="7" type="ORF">A0J61_00611</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the aldo/keto reductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000014">
        <property type="protein sequence ID" value="OBZ91354.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NV47"/>
    <dbReference type="FunCoup" id="A0A1C7NV47">
        <property type="interactions" value="460"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NV47"/>
    <dbReference type="InParanoid" id="A0A1C7NV47"/>
    <dbReference type="OrthoDB" id="416253at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.100:FF:000007">
        <property type="entry name" value="NAD(P)H-dependent D-xylose reductase xyl1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="entry name" value="NADP-dependent oxidoreductase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020471">
        <property type="entry name" value="AKR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018170">
        <property type="entry name" value="Aldo/ket_reductase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036812">
        <property type="entry name" value="NAD(P)_OxRdtase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023210">
        <property type="entry name" value="NADP_OxRdtase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11732">
        <property type="entry name" value="ALDO/KETO REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00248">
        <property type="entry name" value="Aldo_ket_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000097">
        <property type="entry name" value="AKR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00069">
        <property type="entry name" value="ALDKETRDTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51430">
        <property type="entry name" value="NAD(P)-linked oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00063">
        <property type="entry name" value="ALDOKETO_REDUCTASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NADP-dependent oxidoreductase" evidence="6">
        <location>
            <begin position="18"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="3">
        <location>
            <position position="51"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="109"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="site" description="Lowers pKa of active site Tyr" evidence="5">
        <location>
            <position position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007905"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR000097-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR000097-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR000097-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OBZ91354.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="302" mass="33813" checksum="58DC507FB1A64BA4" modified="2016-11-30" version="1">MSNTAVLTLNTGAKMPQIGLGTWQSKPNEVYEAVLTAIKTGYKHIDAAYIYGNEKEVGKAIKDSGIPRSELFVTTKLWNTFHRPEDVEKALQKSLDNLGLDYVDLYLMHWPVAFKAGEDNSPKGEDGKTLFEDVDFTETYAAMEKLDKNKVRAIGVSNFNVTKLEKLAKTQKIVPAANQVELHPYLPQDELVNYCKEKGIIVTAYSPLGSTDSPLLKDEVVAKIAEKNKVSPAQILISWGAKRGYSVIPKSVTASRIKANFEIVDLSDDDFETLNKIVHSQKKQRLVDPYNFWGVDVFDEHE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7M0P1</accession>
    <name>A0A1C7M0P1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_11893</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01002654">
        <property type="protein sequence ID" value="OBZ70513.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7M0P1"/>
    <dbReference type="InParanoid" id="A0A1C7M0P1"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ70513.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="46" mass="5236" checksum="1E7E34FCDC752F2C" modified="2016-11-30" version="1" fragment="single">MFSSSASQNSSQLFKCECSACQLSIPDGYTFIKKRTYNDHQKRDAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7M5H0</accession>
    <name>A0A1C7M5H0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Protein SSH4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">SSH4</name>
        <name evidence="2" type="ORF">A0J61_11878</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01002631">
        <property type="protein sequence ID" value="OBZ71998.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7M5H0"/>
    <dbReference type="STRING" id="101091.A0A1C7M5H0"/>
    <dbReference type="InParanoid" id="A0A1C7M5H0"/>
    <dbReference type="OrthoDB" id="258495at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008888954" evidence="1">
        <location>
            <begin position="28"/>
            <end position="146"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ71998.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="146" mass="16609" checksum="2BC3FB4A5ABE4D40" modified="2016-11-30" version="1">MLALWILGVVLFFVTTIFLVCFTKASSESAISLDNYIDYDDWPTDSEESIANLPEDARLSYERARVFQERHPPDSIPTDITPPQFISIQEKGVSAFEFEGEPDANVYVAARTELQFIHGECCIQTNLPLPRHQEVYYWEGAENEAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MTM0</accession>
    <name>A0A1C7MTM0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Tigger transposable element-derived protein 6</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">TIGD6_1</name>
        <name evidence="3" type="ORF">A0J61_11783</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01002484">
        <property type="protein sequence ID" value="OBZ80168.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MTM0"/>
    <dbReference type="STRING" id="101091.A0A1C7MTM0"/>
    <dbReference type="InParanoid" id="A0A1C7MTM0"/>
    <dbReference type="OrthoDB" id="2392502at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050863">
        <property type="entry name" value="CenT-Element_Derived"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004875">
        <property type="entry name" value="DDE_SF_endonuclease_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006600">
        <property type="entry name" value="HTH_CenpB_DNA-bd_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19303:SF73">
        <property type="entry name" value="PROTEIN PDC2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19303">
        <property type="entry name" value="TRANSPOSON"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03184">
        <property type="entry name" value="DDE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03221">
        <property type="entry name" value="HTH_Tnp_Tc5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00674">
        <property type="entry name" value="CENPB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51253">
        <property type="entry name" value="HTH_CENPB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH CENPB-type" evidence="2">
        <location>
            <begin position="52"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="345"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51253"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ80168.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="345" mass="39770" checksum="0A33967429275922" modified="2016-11-30" version="1" fragment="single">KQKLFENNNWSYSKLGAWAKEEFDLEKPLSKDVISRIIQDESLLFMSETDLQKKSKKTTNLVALEEQVEKFVLDMQARQLPVSEYLISSMALRFAKDMQIEEEFNASKGLFDRFVSRKSLRSFNLHGFEHGFIYYHNSKAWMAKHIFNKMMRLIDRRMDVMNRKILLLLDNASSHSKDLALKNVRPEHLSANTISRVQPLDAGIITNFKSNYNLCGCKYMRNREATENMYKVNQLDAIHFCKAAWNLVTPQTITNCFQHTTLMKGKTVSTAFNEEEEAEVASALESIRQPVNAESEGMMEQVEAAVYDLAVDEDSIQVRKDLTLDDDEDFSIVDEANEGDEAEDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MTZ2</accession>
    <name>A0A1C7MTZ2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Helitron helicase-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_11596</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01002234">
        <property type="protein sequence ID" value="OBZ80355.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7MTZ2"/>
    <dbReference type="InParanoid" id="A0A1C7MTZ2"/>
    <dbReference type="OrthoDB" id="2269493at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025476">
        <property type="entry name" value="Helitron_helicase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14214">
        <property type="entry name" value="Helitron_like_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helitron helicase-like" evidence="1">
        <location>
            <begin position="56"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="unsure residue" description="D or N" evidence="2">
        <location>
            <position position="276"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="386"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF14214"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ80355.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="386" mass="44956" checksum="F7A5696C39F3A63A" modified="2016-11-30" version="1" fragment="single">FLALVFPYLYTNCTGHCSLIPTHTNVFKNRNGIYGLPARQEGVAKATLNGKSLGYYAKTRLLAKDRRFARDPSFLFFMLDLIGKRNIAAANXFVVSTKGRENFKRSDVVDSSTNKLKKNIVSTVPPQIRSSYSYKRKNFLDLQCIFDNLGPPQLFLTFTCDDKNPEFQGLSDEDIKFSWEDPVMFSRHFKRKWQKFYTDYICKNFARQIGXIKEYSWVMEVQDRGSPHIYMVLWTNKSVQELIDMNIVHTWFPQDSTNDPLLYRLIENLQVHRCNDNYCKRADPTRKCRFDYPKPYSDGTLIEDNSNVIYKRDVGDAQVNSYNPYLLATFRIGMDIQYNNGPQAVRYLAKILLKNCTSFVSKRDHYQTRIVGAVEATYDVLGWTKH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MUQ2</accession>
    <name>A0A1C7MUQ2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_11360</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001949">
        <property type="protein sequence ID" value="OBZ80591.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MUQ2"/>
    <dbReference type="InParanoid" id="A0A1C7MUQ2"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="37"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="8"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="50"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ80591.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="66" mass="6977" checksum="06667756E8F2B0BB" modified="2016-11-30" version="1">MELDNEVCTETSPTEIISTFSPGSPVLDEYTMVPLATANGPLPTSPPSPIQHTINITTDTAPIKHG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-06-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MV02</accession>
    <name>A0A1C7MV02_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_11353</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001941">
        <property type="protein sequence ID" value="OBZ80598.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MV02"/>
    <dbReference type="InParanoid" id="A0A1C7MV02"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ80598.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="98" mass="11868" checksum="35C0F3296F3F5830" modified="2016-11-30" version="1" fragment="single">MHSISMFRNRFEYLGQQFKFHTQCEPYLQEEENKGICLFFLEMVQVLPINYNNTTNEHYKQTFMNNDYLHQQQMPIPMPVPMINPMMPPHPHHPKTMP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MVS1</accession>
    <name>A0A1C7MVS1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_11424</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01002020">
        <property type="protein sequence ID" value="OBZ80526.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MVS1"/>
    <dbReference type="InParanoid" id="A0A1C7MVS1"/>
    <dbReference type="OrthoDB" id="25131at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ80526.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="30" mass="3575" checksum="A754EE43EEF7BB14" modified="2016-11-30" version="1" fragment="single">MQAGSLFNTPSLFQPMIPNRRLEMLLRHFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MWR7</accession>
    <name>A0A1C7MWR7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Helitron helicase-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_10709</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001332">
        <property type="protein sequence ID" value="OBZ81243.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7MWR7"/>
    <dbReference type="InParanoid" id="A0A1C7MWR7"/>
    <dbReference type="OrthoDB" id="2282872at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051055">
        <property type="entry name" value="PIF1_helicase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47642">
        <property type="entry name" value="ATP-DEPENDENT DNA HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47642:SF5">
        <property type="entry name" value="ATP-DEPENDENT DNA HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008889340" description="Helitron helicase-like domain-containing protein" evidence="1">
        <location>
            <begin position="20"/>
            <end position="414"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ81243.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="414" mass="48199" checksum="9A7A4AF2E191340E" modified="2016-11-30" version="1">MAMVHQLGIPTLFVTLSAAETKWXELLNFENTWKPPPGPFGDFAIKDYCFRIEFQHRGSPHAHMMIWLEGAPSIDLDVTIPAVKEANRKDVCAFVDAVMTSNAHYPDFDDNFKELIALRQSHHHTKACFKKSKKIQNCRFAIPIFPMDETVVLDPLPDRDNSDYARWVKQVRKYLDDNHNTLSSSNLTFDQFISIFDLSKSNYLTAVRSTLKTSKVFLKREVKHACINQFDPKILKMHRANIDILYELAAAYYNVNEVSAQEAKYNLLQLRMCDASRKTEFVATGSPEYRRRMLKSKDELEGMNRHSSDVYKKGMIEYYQARPDDLEQLNLAQFVANYEFFSKKRARTTDDDADNANDDADNDENLREVSRFIALKDKLGYVKKRKQTKVIRYHLQGINKNPDWFFYRGRSQTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MX23</accession>
    <name>A0A1C7MX23_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_10972</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001549">
        <property type="protein sequence ID" value="OBZ80979.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MX23"/>
    <dbReference type="InParanoid" id="A0A1C7MX23"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="50"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="55"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ80979.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="223" mass="24491" checksum="BE244F8831392A58" modified="2016-11-30" version="1">MFTVYQCPNCVSFYANTQMELTAHINSTQCAYNSAVVATEETQAVESVVTPSENATSSVATSSDVVSEDTNMSSNSDVDVGEVDFSVEPKDVDVSLPIIDENVNSTDSVTYKWTLSEPLSEAKAAWITVMQVLDEAKTPRKYQRKLINVVNSRILSGIDQGPFANETFLFPDTYRRMVQGSTSTTVKHDICPNGCYLFGSDDSTTMACTVLVCKAHRYSTRPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-06-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MXL1</accession>
    <name>A0A1C7MXL1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_10433</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001171">
        <property type="protein sequence ID" value="OBZ81518.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MXL1"/>
    <dbReference type="InParanoid" id="A0A1C7MXL1"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ81518.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="85" mass="9924" checksum="2D0133B14DAD83A5" modified="2016-11-30" version="1">MYLFKSFKVQAIGGIVDCNLMYYLTFSFESRLGVVLECKHMQLLAALLKASKLSNFRLMYLYLISLLQDITVLRRNHLIDCEQIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MYN2</accession>
    <name>A0A1C7MYN2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Protein transport protein Sec61 subunit gamma</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">9G6.310</name>
        <name evidence="11" type="ORF">A0J61_09926</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SecE/SEC61-gamma family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000973">
        <property type="protein sequence ID" value="OBZ82025.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MYN2"/>
    <dbReference type="FunCoup" id="A0A1C7MYN2">
        <property type="interactions" value="329"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7MYN2"/>
    <dbReference type="InParanoid" id="A0A1C7MYN2"/>
    <dbReference type="OrthoDB" id="2401875at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005637">
        <property type="term" value="C:nuclear inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005784">
        <property type="term" value="C:Sec61 translocon complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071261">
        <property type="term" value="C:Ssh1 translocon complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015450">
        <property type="term" value="F:protein-transporting ATPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005198">
        <property type="term" value="F:structural molecule activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031204">
        <property type="term" value="P:post-translational protein targeting to membrane, translocation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006616">
        <property type="term" value="P:SRP-dependent cotranslational protein targeting to membrane, translocation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.820">
        <property type="entry name" value="Preprotein translocase SecE subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00422">
        <property type="entry name" value="SecE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023391">
        <property type="entry name" value="Prot_translocase_SecE_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008158">
        <property type="entry name" value="Translocase_Sec61-g"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001901">
        <property type="entry name" value="Translocase_SecE/Sec61-g"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00327">
        <property type="entry name" value="secE_euk_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12309">
        <property type="entry name" value="SEC61 GAMMA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00584">
        <property type="entry name" value="SecE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103456">
        <property type="entry name" value="Preprotein translocase SecE subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0811">Translocation</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="41"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="OBZ82025.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="13">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="74" mass="8140" checksum="36255A4AE804BAD3" modified="2016-11-30" version="1">MSSDLKETAQQVVDGPKQFFKEGVQFINRCKKPDQQEYLKITQAVAMGFAALGALGYFVKLIHIPINNILVGAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MZ01</accession>
    <name>A0A1C7MZ01_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">N-alpha-acetyltransferase 30</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">NAA30</name>
        <name evidence="5" type="ORF">A0J61_09870</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the acetyltransferase family. MAK3 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000959">
        <property type="protein sequence ID" value="OBZ82080.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MZ01"/>
    <dbReference type="FunCoup" id="A0A1C7MZ01">
        <property type="interactions" value="17"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7MZ01"/>
    <dbReference type="InParanoid" id="A0A1C7MZ01"/>
    <dbReference type="OrthoDB" id="249099at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031417">
        <property type="term" value="C:NatC complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000822">
        <property type="term" value="F:inositol hexakisphosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004596">
        <property type="term" value="F:protein-N-terminal amino-acid acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032880">
        <property type="term" value="P:regulation of protein localization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd04301">
        <property type="entry name" value="NAT_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044542">
        <property type="entry name" value="NAA30-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45896">
        <property type="entry name" value="N-ALPHA-ACETYLTRANSFERASE 30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45896:SF1">
        <property type="entry name" value="N-ALPHA-ACETYLTRANSFERASE 30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="4">
        <location>
            <begin position="2"/>
            <end position="150"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00024025"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OBZ82080.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="165" mass="19377" checksum="CD67419EEED3504C" modified="2016-11-30" version="1">MIEYSEFQSEVQLPEIIHLIENDLSEPYSVYTYRYFIHNWPNLCFLAKEENAYVGVIICKLDRHKDRLRGYIAMLAVAKTHRKRSIGSNLVKKALYAMKKMNADEVVLETEYTNLGALGLYQKLGFIRDKRLYRYYLNGIDAFRLKLFCKTMMPSKEQEEGSAII</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MZ44</accession>
    <name>A0A1C7MZ44_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_10265</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001092">
        <property type="protein sequence ID" value="OBZ81686.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MZ44"/>
    <dbReference type="InParanoid" id="A0A1C7MZ44"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ81686.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="94" mass="10335" checksum="4FD9EA9F8BA889A8" modified="2016-11-30" version="1">MTDVSHCQLHHLPVVWANHSLLTFELAASDVPTGSGAWRSDPALLLDKHFTDLFTVSVDTFLTQVVFEGLQIPLGGCLHVHTEPHNASPVPERQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MZS6</accession>
    <name>A0A1C7MZS6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Transferrin receptor-like dimerisation domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_09555</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000877">
        <property type="protein sequence ID" value="OBZ82395.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MZS6"/>
    <dbReference type="STRING" id="101091.A0A1C7MZS6"/>
    <dbReference type="InParanoid" id="A0A1C7MZS6"/>
    <dbReference type="OrthoDB" id="5841748at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.930.40">
        <property type="entry name" value="Transferrin receptor-like, dimerisation domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039373">
        <property type="entry name" value="Peptidase_M28B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007365">
        <property type="entry name" value="TFR-like_dimer_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036757">
        <property type="entry name" value="TFR-like_dimer_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10404">
        <property type="entry name" value="N-ACETYLATED-ALPHA-LINKED ACIDIC DIPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10404:SF46">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04253">
        <property type="entry name" value="TFR_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47672">
        <property type="entry name" value="Transferrin receptor-like dimerisation domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Transferrin receptor-like dimerisation" evidence="1">
        <location>
            <begin position="3"/>
            <end position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF04253"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ82395.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="110" mass="12736" checksum="A78BC6FA8159EDF9" modified="2016-11-30" version="1">MSDNFQTNMLKWANSSLLNKNYLHNLRKHIKTINERLIQLERTFIHVEGISPDRPWFGHVLYGPDLYTGSSVLFPGLSEAMEKDNATLALWAEERIVEAIHQAEKTLSRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N0W1</accession>
    <name>A0A1C7N0W1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_09236</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000805">
        <property type="protein sequence ID" value="OBZ82713.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N0W1"/>
    <dbReference type="InParanoid" id="A0A1C7N0W1"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ82713.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="83" mass="8962" checksum="A844CB260098E7AC" modified="2016-11-30" version="1">MANKDARWSAPGSVTICDLFRIGLLLDPVSTDVDGLLRLQPDYGPVGGAPSRTDETDVNARTGIATEIWTEEDLDVIEDEGTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N0Y5</accession>
    <name>A0A1C7N0Y5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Phospholipase DDHD1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">Ddhd1</name>
        <name evidence="2" type="ORF">A0J61_09207</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000797">
        <property type="protein sequence ID" value="OBZ82743.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N0Y5"/>
    <dbReference type="STRING" id="101091.A0A1C7N0Y5"/>
    <dbReference type="InParanoid" id="A0A1C7N0Y5"/>
    <dbReference type="OrthoDB" id="431378at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004620">
        <property type="term" value="F:phospholipase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004177">
        <property type="entry name" value="DDHD_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058055">
        <property type="entry name" value="PA-PLA1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23509:SF10">
        <property type="entry name" value="LD21067P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23509">
        <property type="entry name" value="PA-PL1 PHOSPHOLIPASE FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02862">
        <property type="entry name" value="DDHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01127">
        <property type="entry name" value="DDHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51043">
        <property type="entry name" value="DDHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DDHD" evidence="1">
        <location>
            <begin position="187"/>
            <end position="411"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ82743.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="413" mass="47756" checksum="C45A67E45A18F786" modified="2016-11-30" version="1">MLEDQAVKEDVYSDHLVFFIHGMGQQYEKYGNMKHHVSTMQKNTTEILSSRYPNRKIRVKYIPIEWHSEVHKMVDDKINRSTLNTVPKVRLTTNEWLMDCLYYFSKPHGQYIIDSVCNQCNSAYLQHKSNHPGFKGDVHFIGFSLGGIIAYDIASMQWLQEDGLPPWHDTGLEESVCRTPDIKVPLLDFKIRSVFTCGSPIAAGLVCRGLDYVHYRPPFRTKIYNIFHPFDPLGYRLEPMVNSDYESIEPVQIDRMKRYSSPLPKIPNLGIRSSIAGAKPLLQSFWQYVSSTVIKNELDSRTPEKELHIATNDVTVSKKRAHEEEGRHCDKKRRLSSMSQEQVRVETESSKEAIAFSIEGQDGCLYPRTDYVLSENLIDAYASEWIVALKSHFRYWANRDLALHIIKVFLNES</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N114</accession>
    <name>A0A1C7N114_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">DUF788-domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">A0J61_09642</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TMEM208 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000898">
        <property type="protein sequence ID" value="OBZ82309.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N114"/>
    <dbReference type="FunCoup" id="A0A1C7N114">
        <property type="interactions" value="5"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N114"/>
    <dbReference type="InParanoid" id="A0A1C7N114"/>
    <dbReference type="OrthoDB" id="276296at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005773">
        <property type="term" value="C:vacuole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006624">
        <property type="term" value="P:vacuolar protein processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008506">
        <property type="entry name" value="SND2/TMEM208"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13505">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 208"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13505:SF7">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 208"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05620">
        <property type="entry name" value="TMEM208_SND2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="20"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="49"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="93"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="144"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="144"/>
            <end position="154"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009950"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OBZ82309.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="177" mass="19897" checksum="6733E9D48EA6ADCD" modified="2016-11-30" version="1">MANASSKKIASQNKQTLANLQKGFLIVNAIYFLWRIVYHWSSFSLSQFILYITTMGLSVLLYRVLISSGSPVYASDGSLIQSGDDLNSEGLTAYMFDIIYVTWFVHITTAFISNKFWYTYLVIPGYAAYKLVPMIMSYLGKGQTSVDEADSSNGKSKRQIKMEKRASKGGQVKYATR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N1B7</accession>
    <name>A0A1C7N1B7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Protease KEX1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">KEX1_0</name>
        <name evidence="12" type="ORF">A0J61_09070</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S8 family. Furin subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000767">
        <property type="protein sequence ID" value="OBZ82877.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N1B7"/>
    <dbReference type="FunCoup" id="A0A1C7N1B7">
        <property type="interactions" value="58"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N1B7"/>
    <dbReference type="InParanoid" id="A0A1C7N1B7"/>
    <dbReference type="OrthoDB" id="300641at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005802">
        <property type="term" value="C:trans-Golgi network"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007323">
        <property type="term" value="P:peptide pheromone maturation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016485">
        <property type="term" value="P:protein processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd04059">
        <property type="entry name" value="Peptidases_S8_Protein_convertases_Kexins_Furin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.200:FF:000005">
        <property type="entry name" value="Proprotein convertase subtilisin/kexin type 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.260">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.850">
        <property type="entry name" value="Peptidase S8, pro-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.200">
        <property type="entry name" value="Peptidase S8/S53 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008979">
        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034182">
        <property type="entry name" value="Kexin/furin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002884">
        <property type="entry name" value="P_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000209">
        <property type="entry name" value="Peptidase_S8/S53_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036852">
        <property type="entry name" value="Peptidase_S8/S53_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022398">
        <property type="entry name" value="Peptidase_S8_His-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023828">
        <property type="entry name" value="Peptidase_S8_Ser-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015500">
        <property type="entry name" value="Peptidase_S8_subtilisin-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038466">
        <property type="entry name" value="S8_pro-domain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42884:SF14">
        <property type="entry name" value="NEUROENDOCRINE CONVERTASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42884">
        <property type="entry name" value="PROPROTEIN CONVERTASE SUBTILISIN/KEXIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01483">
        <property type="entry name" value="P_proprotein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00082">
        <property type="entry name" value="Peptidase_S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00723">
        <property type="entry name" value="SUBTILISIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49785">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52743">
        <property type="entry name" value="Subtilisin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51829">
        <property type="entry name" value="P_HOMO_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51892">
        <property type="entry name" value="SUBTILASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00137">
        <property type="entry name" value="SUBTILASE_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00138">
        <property type="entry name" value="SUBTILASE_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0106">Calcium</keyword>
    <keyword evidence="4 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 8 12" id="KW-0645">Protease</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0720">Serine protease</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="733"/>
            <end position="756"/>
        </location>
    </feature>
    <feature type="domain" description="P/Homo B" evidence="11">
        <location>
            <begin position="502"/>
            <end position="638"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="659"/>
            <end position="724"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="789"/>
            <end position="812"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="664"/>
            <end position="674"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="685"/>
            <end position="699"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="700"/>
            <end position="712"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="789"/>
            <end position="802"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="7 8">
        <location>
            <position position="217"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="7 8">
        <location>
            <position position="255"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="7 8">
        <location>
            <position position="427"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005325"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR615500-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="OBZ82877.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="812" mass="90117" checksum="A3B5E3410AF4E23C" modified="2016-11-30" version="1">MVADHVALLSQAGYGYLQQFKHRCRICEDILDMVNYRLATIALWVAAISPFAQAQTYMGKREADRDYYTVHVDSRDGAQHLAKRLNVRYEGNVGELDSWHMFSTPKLVKRATQENEEEDRVLVAFEQLKSTLSKRDNVHWQNAHSLTKQVYKKRTKRGPIPVDYKIEQAKEKLSIDDPWFPRQWHLINQINPGNDINVTGVWEQGITGKGVNVVILDDGLDYKSKDLADNFYAEGSYDFNDHEDLPTPKLWDDSHGTRCAGQIAAVKNDVCGVGIAYGAKVAGVRILSGELSDADEALALNYKYQKNHIFSCSWGPPDNGQTMEAPKGILADAFMNGIKKGRDGKGSIYVFATGNGGISGDNCNFDGYTNSIYTITVGAIDFRDQHPPYSEACSAQLVVTYSSGGGKYIHTTDVGTDSCSDRHGGTSAAAPNAAGIFALVLSVRPDLSWRDLQHLCVQTAVPVNLDDGDWKKLPSGRLYNHKYGYGKLDAYALVEAAKTFELVNQQTWLELPSPVKRRFIPDSTDLKTRKALKNIVVVTQGMIEAAGLLRLEHITATVNIQHQRRGSIVIDLESPNHVKSELATRRVLDSDETGMHNWKFMEEDPVGNWTLSVYDVDNPETTGYMFNWTLTLFGEMDPKFEGTPIHTTIGFHEDKEHEVPVISTTKEPVTTTLTEHVPARPTRVKPSSSSANHQDNVVNQQSSTQPSTESPTGDAQIENEKEAENISDKDNGYLTIVYGVVGSAAIFGIAVGLFFYQKHGFSGNVTAADRNVGPGGYEFDVLQPLTELDEDELVDSDRDEDESGRLVRNNSH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N1C9</accession>
    <name>A0A1C7N1C9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Subtilisin inhibitor domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_09055</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000763">
        <property type="protein sequence ID" value="OBZ82893.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N1C9"/>
    <dbReference type="InParanoid" id="A0A1C7N1C9"/>
    <dbReference type="OrthoDB" id="2278061at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004867">
        <property type="term" value="F:serine-type endopeptidase inhibitor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.350.10">
        <property type="entry name" value="Subtilisin inhibitor-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023549">
        <property type="entry name" value="Subtilisin_inhibitor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036819">
        <property type="entry name" value="Subtilisin_inhibitor-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00720">
        <property type="entry name" value="SSI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55399">
        <property type="entry name" value="Subtilisin inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008889411" description="Subtilisin inhibitor domain-containing protein" evidence="1">
        <location>
            <begin position="19"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="domain" description="Subtilisin inhibitor" evidence="2">
        <location>
            <begin position="34"/>
            <end position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00720"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ82893.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="118" mass="13021" checksum="1AB4B62493E66D42" modified="2016-11-30" version="1">MLSRVFFMLLLLTLVVRATPLASLKITILGFRQARRYSLTCDPTGGSHTAADGACDILDDIGGNISSLPTVSANGRSHPVYVSIEGYYHHKPVQFFKNYRNEATAITELDGLYPEEED</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N1T4</accession>
    <name>A0A1C7N1T4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">WH1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_10616</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001272">
        <property type="protein sequence ID" value="OBZ81334.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N1T4"/>
    <dbReference type="STRING" id="101091.A0A1C7N1T4"/>
    <dbReference type="InParanoid" id="A0A1C7N1T4"/>
    <dbReference type="OrthoDB" id="8963340at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000697">
        <property type="entry name" value="WH1/EVH1_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00568">
        <property type="entry name" value="WH1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50229">
        <property type="entry name" value="WH1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="WH1" evidence="1">
        <location>
            <begin position="17"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ81334.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="81" mass="9034" checksum="28C937B6DE3DF81A" modified="2016-11-30" version="1" fragment="single">MKSVTLPSAEDKDNVRKAVPTSKILMAAVARLFVASPDPSKWTYTHLWGAAVFCTDKSKNNGHFIRMVDIEKGKGVVWEQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N230</accession>
    <name>A0A1C7N230_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="17">Putative global transcription activator SNF2L1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="17" type="primary">Smarca1</name>
        <name evidence="17" type="ORF">A0J61_08902</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SNF2/RAD54 helicase family. ISWI subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000732">
        <property type="protein sequence ID" value="OBZ83048.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N230"/>
    <dbReference type="STRING" id="101091.A0A1C7N230"/>
    <dbReference type="InParanoid" id="A0A1C7N230"/>
    <dbReference type="OrthoDB" id="5857104at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031010">
        <property type="term" value="C:ISWI-type complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140658">
        <property type="term" value="F:ATP-dependent chromatin remodeler activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042393">
        <property type="term" value="F:histone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031491">
        <property type="term" value="F:nucleosome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034728">
        <property type="term" value="P:nucleosome organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd17997">
        <property type="entry name" value="DEXHc_SMARCA1_SMARCA5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00167">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18793">
        <property type="entry name" value="SF2_C_SNF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000082">
        <property type="entry name" value="ISWI chromatin remodeling complex ATPase ISW1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.60:FF:000022">
        <property type="entry name" value="ISWI chromatin-remodeling complex ATPase CHR11 isoform A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.10810:FF:000002">
        <property type="entry name" value="ISWI chromatin-remodeling complex ATPase CHR11 isoform A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1040.30">
        <property type="entry name" value="ISWI, HAND domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10810">
        <property type="entry name" value="Tandem AAA-ATPase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044754">
        <property type="entry name" value="Isw1/2_DEXHc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015194">
        <property type="entry name" value="ISWI_HAND-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036306">
        <property type="entry name" value="ISWI_HAND-dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001005">
        <property type="entry name" value="SANT/Myb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017884">
        <property type="entry name" value="SANT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015195">
        <property type="entry name" value="SLIDE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038718">
        <property type="entry name" value="SNF2-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049730">
        <property type="entry name" value="SNF2/RAD54-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000330">
        <property type="entry name" value="SNF2_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45623">
        <property type="entry name" value="CHROMODOMAIN-HELICASE-DNA-BINDING PROTEIN 3-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45623:SF49">
        <property type="entry name" value="SWI_SNF-RELATED MATRIX-ASSOCIATED ACTIN-DEPENDENT REGULATOR OF CHROMATIN SUBFAMILY A MEMBER 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09110">
        <property type="entry name" value="HAND"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09111">
        <property type="entry name" value="SLIDE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00176">
        <property type="entry name" value="SNF2-rel_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00717">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101224">
        <property type="entry name" value="HAND domain of the nucleosome remodeling ATPase ISWI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51293">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="7" id="KW-0347">Helicase</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-0539">Nucleus</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="11" id="KW-0804">Transcription</keyword>
    <keyword evidence="10" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="14">
        <location>
            <begin position="103"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="15">
        <location>
            <begin position="400"/>
            <end position="551"/>
        </location>
    </feature>
    <feature type="domain" description="SANT" evidence="16">
        <location>
            <begin position="762"/>
            <end position="814"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="42"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="717"/>
            <end position="748"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="936"/>
            <end position="973"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="13">
        <location>
            <begin position="59"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="726"/>
            <end position="744"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="955"/>
            <end position="973"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="17">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS51293"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="OBZ83048.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="973" mass="113454" checksum="A2B34DC70EA1014C" modified="2016-11-30" version="1" fragment="single">YETRIKRYRYLLGQTELFAHFLNLKDIKDDAMKAVLKEKELQKSNADDGSRRRRKTEKEEDEEILKDEQQENEDETTVFTQSPSYVTGGTLREYQIQGLNWMISLFENGINGILADEMGLGKTLQTISFLGYLKHVRGIKGPHLVVVPKSTLHNWHNEFKKWVPDFNAFVFHGDKDARAQLIKDRILPGDFEVCITSYEICLLEKTQFKKVKWQYIIVDEAHRIKNENSMLSQLVRILQSRNRLLITGTPLQNNLHELWALLNFLLPDVFSSSEVFDEWFEKQGGDQKKVVEQLHKVLRPFLLRRIKSDVEKSLLPKKEINVYVRMSPMQRQWYQKILEKDIDAINGVGVNKREGKTRLLNIVMQLRKCCNHPYLFDGAEPGPPFTTDQHLVDNAGKMVVLDKLLKKCKAQGSRVLLFSQMSRVLDILEDYCWWKDYQYCRIDGQTSQEERIDAIDEYNRPGSDKFIFLLTTRAGGLGINLTTADVVVLYDSDWNPQVDLQAMDRAHRIGQTKQVYVFRFVTENAIEEKVLERAAQKLRLDQLVIQQGRMNTGQKSKTASKEDLLTMIQHGAENIFKDGNENDDTTDDIDEILRVGEEKTAELNNKYSNLNIDDLKNFSSESAYKWDGEDWSHKRKAESVGLSWLGPAKRERKANYAVDDYYKEALRTSARTPSTKAPRPKKYNIEDFQFFPPRLAELNERDTLYLRKSLGYKIPPVNAEEGATEEDIKQLEQERQEEQKKIDLAEPLTEEEEEERKELFTKGFSNWSKKDFAIFINACAKYGRKDLQSITAELEGKTLDEVKKYAKIFWSRYKEIADYERHISKIERGENELEKQADIQGQLTEKVQRHRVPLQQLKIHYTQPTKGKNYTEEEDRFLVVMLEKYGYGTENVYDHIRREIKQSPLFRFDWFLKSRTSQEVARRCNTLISLIQKENAELEEAEEKKPQAKNKSGRSKSSTPVASVTATSKSKRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N249</accession>
    <name>A0A1C7N249_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Peroxisomal ATPase PEX6</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Peroxin-6</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="primary">PEX6</name>
        <name evidence="13" type="ORF">A0J61_08765</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="10">
            <dbReference type="Rhea" id="RHEA:13066"/>
        </physiologicalReaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the AAA ATPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000707">
        <property type="protein sequence ID" value="OBZ83182.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N249"/>
    <dbReference type="FunCoup" id="A0A1C7N249">
        <property type="interactions" value="125"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N249"/>
    <dbReference type="InParanoid" id="A0A1C7N249"/>
    <dbReference type="OrthoDB" id="5553750at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005778">
        <property type="term" value="C:peroxisomal membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016558">
        <property type="term" value="P:protein import into peroxisome matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd19527">
        <property type="entry name" value="RecA-like_PEX6_r2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000109">
        <property type="entry name" value="Peroxisomal biogenesis factor 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.60:FF:000039">
        <property type="entry name" value="peroxisome biogenesis factor 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050168">
        <property type="entry name" value="AAA_ATPase_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041569">
        <property type="entry name" value="AAA_lid_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003960">
        <property type="entry name" value="ATPase_AAA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056995">
        <property type="entry name" value="PEX6_4th_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047533">
        <property type="entry name" value="RecA-like_PEX6_r2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23077">
        <property type="entry name" value="AAA-FAMILY ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23077:SF9">
        <property type="entry name" value="PEROXISOMAL ATPASE PEX6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17862">
        <property type="entry name" value="AAA_lid_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23315">
        <property type="entry name" value="PEX6_4th"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00674">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3" id="KW-0962">Peroxisome biogenesis</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="12">
        <location>
            <begin position="521"/>
            <end position="660"/>
        </location>
    </feature>
    <feature type="domain" description="AAA+ ATPase" evidence="12">
        <location>
            <begin position="802"/>
            <end position="947"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1074"/>
            <end position="1124"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="1085"/>
            <end position="1095"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="11">
        <location>
            <begin position="1109"/>
            <end position="1124"/>
        </location>
    </feature>
    <feature type="unsure residue" description="D or N" evidence="13">
        <location>
            <position position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006914"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00034811"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00034920"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00048778"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="OBZ83182.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="1124" mass="124302" checksum="6428C1DD1D53C241" modified="2016-11-30" version="1">MPFCTTGNIRLTFEDHQDQHVFVSQKLWQEIAPASQTQDSVPVSVTIPSLVSSSPLKLDDRPSLKNFLAYCRPAEEKEEGHYVYISSHLIQTMYGKDALNQLDEDEEDTLCTVELKKIELIELDELVLGALNEKSYKFAQTDQEALAKLLMGQSRQIIRGSEQYKFENDLSYKILMTSPVQQGYIAAADRTQIITMDLSADVEEETIDGNDTPAKANHHAFNLLQSTSKPDVIEPKEFSVRILQKRWPEIRLWPAPVDSDDDESRIYIDIKDLAQCGVFSGDWVLVSGNNPKRSRLCRVYGIDDETGSQGIAFLPPPLYFNLDLPLPPAPIDEARITVTRIHANSTENPPVASSVTIARIASPASMDKAFQSVFLESLKAWFEAKERIVCKGDVIAISLNEDTARLKPQDEDLVGQEISFLQKEPTTLVYFKVTSLECHTEVDNSQHPHPSYFGSGRRIVPSKTQMIQTGVEYSRVPCGSLSHYYGFFKKLPLMRSQSLAHQQLYELVSSSLHPLSRDFELSCNALFHGPRGGGKTTLVKEVAEELGVHLYEFSVYDIISDTDAKTEVHLRAKFDKAAALAPCVVLMRHMEGLAKKSAVVESGQEPLLATVLQECIKNVNNSHASTGYPVMVIATASDVDALPSSILSCFRHEISIGAPDEKSRYQILQDLLIDSPLAPDVSLSSLATQTAALVAKDLVDLVGRAGLLSLQRIDKSIHSKSQATNEICAQDIQAAGIMLTAADFESALGQARSSYSDSIGAPKIPTVTWDDVGGMAHVKDDILDTIQLPLEHPELFGAGLKKRSGILLYGPPGTGKTLLAKAIATSCSLNFFSVKGPELLNMYIGESEANVRRVFQRARDAKPCVIFFDELDSVAPKRGEKGDSGGVMDRIVSQLLAELDGMSEGSGEAAGAGDVFVIGATNRPDLLDPALLRPGRFDKLLYLGVSQDHESQLRIIEALTRKFRLHPDLDLRKVAERCPFHYTGADFYALCSDAMLKAMTRVADTIEEKVKQLNQEKRTDLPQPLTVQYYLSHLVTPEEILVQAEEVDFIKALEELIPSVSATELEHYSKVREKFEQSADEVPEEDKAPVAHEAEESAPIESSPERGKQKVTMKSRKDKGKQRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N2F9</accession>
    <name>A0A1C7N2F9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="1">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">ATG1</name>
        <name evidence="10" type="ORF">A0J61_10405</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="7">Belongs to the protein kinase superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="1"/>
    <dbReference type="EMBL" id="LUGH01001157">
        <property type="protein sequence ID" value="OBZ81544.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N2F9"/>
    <dbReference type="STRING" id="101091.A0A1C7N2F9"/>
    <dbReference type="InParanoid" id="A0A1C7N2F9"/>
    <dbReference type="OrthoDB" id="346907at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005776">
        <property type="term" value="C:autophagosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034045">
        <property type="term" value="C:phagophore assembly site membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000045">
        <property type="term" value="P:autophagosome assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000422">
        <property type="term" value="P:autophagy of mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034727">
        <property type="term" value="P:piecemeal microautophagy of the nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010506">
        <property type="term" value="P:regulation of autophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042594">
        <property type="term" value="P:response to starvation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061709">
        <property type="term" value="P:reticulophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd14009">
        <property type="entry name" value="STKc_ATG1_ULK_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000042">
        <property type="entry name" value="Aurora kinase A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000571">
        <property type="entry name" value="Maternal embryonic leucine zipper kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045269">
        <property type="entry name" value="Atg1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24348:SF22">
        <property type="entry name" value="NON-SPECIFIC SERINE_THREONINE PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24348">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE UNC-51-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 10" id="KW-0418">Kinase</keyword>
    <keyword evidence="3 6 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="9">
        <location>
            <begin position="13"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="351"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="399"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="351"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="377"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="42"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="non-terminal residue" evidence="10">
        <location>
            <position position="442"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OBZ81544.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="442" mass="50069" checksum="F2810D58145BC7C6" modified="2016-11-30" version="1" fragment="single">MSPEKRLEQVGDYIIQNKIGQGSFATVYKAQHKDTQQTVAIKSVKRSKLTKKLLENLESEISILTSIRHENIVGLIECQKTETNIYLVMEFCSLGDLSHYIKQKRPSKDAAGGLEQPVVRHFLRQLANALQFLRSQNLIHRDIKPQNLLLTPDRNPNNLPLLKVADFGFARFLPNASLADTLCGSPLYMGPEILSYKKYDAKADLWSVGAVLYEMVTGRPPFRASNHIELLKKIKENKDQIHFPDHSVVIDSDLKDLIRKLLKMYPVERLSFDEFFQHPAILPYRRTRPTSTYEPPPFIHHLSDSPVQRRYREKPKEEIEDVLQDYVVLNIRSIETNRFADELKATPSMATSHAVNIPRSNRISPSQSPFHRERKSSTGSSSAGSALAKALSMASIRLFGSSMPSPPKDNHVHGSPHGFMSQETSSDHLKTIERLSCMAHAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N335</accession>
    <name>A0A1C7N335_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ATP synthase mitochondrial F1 complex assembly factor 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">ATPAF1</name>
        <name evidence="5" type="ORF">A0J61_10197</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ATP11 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001068">
        <property type="protein sequence ID" value="OBZ81754.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N335"/>
    <dbReference type="FunCoup" id="A0A1C7N335">
        <property type="interactions" value="271"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N335"/>
    <dbReference type="InParanoid" id="A0A1C7N335"/>
    <dbReference type="OrthoDB" id="16535at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033615">
        <property type="term" value="P:mitochondrial proton-transporting ATP synthase complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010591">
        <property type="entry name" value="ATP11"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13126:SF0">
        <property type="entry name" value="ATP SYNTHASE MITOCHONDRIAL F1 COMPLEX ASSEMBLY FACTOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13126">
        <property type="entry name" value="CHAPERONE ATP11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06644">
        <property type="entry name" value="ATP11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0809">Transit peptide</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009116"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OBZ81754.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="294" mass="33226" checksum="964FCB7759963F17" modified="2016-11-30" version="1">MLSRISRQITSNVGAYRKSAYATLQNNILGSRTVQSRFLNAQVRPIDFESKYADKIKDMAKKQGLTVDELKKKIKDDALKRLKAAQPRPVEPKIAKDTAKKASASTIAAKSKLPYDSSAPTLDKFVKLELLEQETPENIEKIWNAGHANKDCITAAIPSDVYNKLYEHGQKYPMFVVPMPREEGVEFFFLQFNFNQCNFTSLLEYKTKGTEARPFLTLTHFTELQESKGIVLMKGDINDDPRMITTANAQFLAFALQQFYVTGGPDKLKLVEKFHTAPGEFDFNELIKAVETVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N346</accession>
    <name>A0A1C7N346_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_08520</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000665">
        <property type="protein sequence ID" value="OBZ83428.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N346"/>
    <dbReference type="InParanoid" id="A0A1C7N346"/>
    <dbReference type="OrthoDB" id="2157595at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33324">
        <property type="entry name" value="EXPRESSED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33324:SF2">
        <property type="entry name" value="MYB_SANT-LIKE DNA-BINDING DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="177"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="258"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="190"/>
            <end position="202"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ83428.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="335" mass="38728" checksum="C790D859AD73DDA0" modified="2016-11-30" version="1">MAITKNTRSKSMNVDWNNDGVKGKRSSQQVILDWISDDGNYSRLKRIGAKENTKTSCYKEIVNTLVAEGITWRTVKNVKSFMKNLEDSYQNAIDLKNSTEIMRSHKEEEGLSQQECSNRMMNDLGFANHCLAGKILETCPHYEILHSVMASQPGTTAFYLSSSTDNDDVAEIIDQATNRRKKAAQQKTRSIKDDQDDMKQLADDDEGDAPSNYKTTNAASAARNKRQKGDLDSMLFEGLQRSEVLYMERTEMERASRKNEYQLKLAQDNKRLEVEKERWEREFELKVNQARFQQEHHRRELRIKEAHAQAEYVKMMFSLGKTPEQVVKAVQDFFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N352</accession>
    <name>A0A1C7N352_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Solute carrier family 35 member F2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">Slc35f2</name>
        <name evidence="9" type="ORF">A0J61_08882</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SLC35F solute transporter family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000728">
        <property type="protein sequence ID" value="OBZ83066.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N352"/>
    <dbReference type="STRING" id="101091.A0A1C7N352"/>
    <dbReference type="InParanoid" id="A0A1C7N352"/>
    <dbReference type="OrthoDB" id="429955at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037185">
        <property type="entry name" value="EmrE-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009262">
        <property type="entry name" value="SLC35_F1/F2/F6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052221">
        <property type="entry name" value="SLC35F_Transporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14233">
        <property type="entry name" value="DUF914-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14233:SF4">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 35 MEMBER F2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06027">
        <property type="entry name" value="SLC35F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103481">
        <property type="entry name" value="Multidrug resistance efflux transporter EmrE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008889452" evidence="8">
        <location>
            <begin position="28"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="87"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="116"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="213"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="237"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="269"/>
            <end position="287"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007863"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OBZ83066.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="318" mass="35256" checksum="6B88608473AD1C29" modified="2016-11-30" version="1">MPTLSKNTVLAVGLGQLLSLCITGTSAASSALWNKYQISIPFTQNFCNYLLLASVYTLIATETRSASTQTHWQCNALAVLAFKRTSVLSALILSSWSIPCIMLLSAFFLNVRYSKLHVQSAIVCLIGLVLLIWGDVMGNEDESTVNHSWIGDMICVHATLYAVSNVTEEHLVQHYDSSEFLRKAGYWGSLFCGIQMLIFEFDHLIAIEWSWPILGLVTMYVLCLFCMYSLVPTVYRMAGAAFLSMNLITSNFYSLIVGLLFLNAKMPPLYPIAYALVITSVTIFSLVSPTTISGQLKQDEESMPISNDSSKRVLYTLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N3C0</accession>
    <name>A0A1C7N3C0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">NAD(P)H dehydrogenase (Quinone) FQR1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">FQR1_0</name>
        <name evidence="4" type="ORF">A0J61_08815</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the WrbA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000716">
        <property type="protein sequence ID" value="OBZ83136.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N3C0"/>
    <dbReference type="FunCoup" id="A0A1C7N3C0">
        <property type="interactions" value="146"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N3C0"/>
    <dbReference type="InParanoid" id="A0A1C7N3C0"/>
    <dbReference type="OrthoDB" id="504689at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003955">
        <property type="term" value="F:NAD(P)H dehydrogenase (quinone) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.360:FF:000001">
        <property type="entry name" value="NAD(P)H dehydrogenase (Quinone) FQR1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.360">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008254">
        <property type="entry name" value="Flavodoxin/NO_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029039">
        <property type="entry name" value="Flavoprotein-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010089">
        <property type="entry name" value="Flavoprotein_WrbA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005025">
        <property type="entry name" value="FMN_Rdtase-like_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01755">
        <property type="entry name" value="flav_wrbA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF002999">
        <property type="entry name" value="PRK03767.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30546">
        <property type="entry name" value="FLAVODOXIN-RELATED PROTEIN WRBA-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30546:SF23">
        <property type="entry name" value="FLAVOPROTEIN-LIKE PROTEIN YCP4-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03358">
        <property type="entry name" value="FMN_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52218">
        <property type="entry name" value="Flavoproteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50902">
        <property type="entry name" value="FLAVODOXIN_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Flavodoxin-like" evidence="3">
        <location>
            <begin position="6"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="230"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="258"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="265"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="302"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="314"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="359"/>
            <end position="373"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006961"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50902"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OBZ83136.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="386" mass="40468" checksum="2E383D320A012AA6" modified="2016-11-30" version="1">MNKPVVYIVIYSLYQHVYKLALSVKEGLEDKGVEVQLFQVAETLPKEVLVKMEAPPKPDIPVITVDKLAEPDGIIFGLPTRFGTMPAQVKALLDASGALWAKGALAGKFAGTFFCTASQHGGQETTAFTIIPYFAHHGMLFVPIGYSHPALGDNEDEQVIGGSSYGAGTVSDGDGSRQPTFVELDIAKHQGAGFGQIVSTFVKGRHIKDPISQSVTADEKDTNQRAVEVDDANVATETNDHEGTEIGGGTATSAAAVTSAVNPDKSADVQVKEGSLEKESDPLGTASDKEAIVNGLSNTKSNLKEGETVEDNTKSNTLGQTESSSKLAGDNTRSGLESSKQHESTTENTAGNIAGDSGAANNKAESNAATQNPKKSKLKSLLCCGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N4E2</accession>
    <name>A0A1C7N4E2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Rab proteins geranylgeranyltransferase component A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">Rep</name>
        <name evidence="2" type="ORF">A0J61_07942</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the Rab GDI family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000570">
        <property type="protein sequence ID" value="OBZ84005.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N4E2"/>
    <dbReference type="STRING" id="101091.A0A1C7N4E2"/>
    <dbReference type="InParanoid" id="A0A1C7N4E2"/>
    <dbReference type="OrthoDB" id="9446342at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005968">
        <property type="term" value="C:Rab-protein geranylgeranyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005092">
        <property type="term" value="F:GDP-dissociation inhibitor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007264">
        <property type="term" value="P:small GTPase-mediated signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016192">
        <property type="term" value="P:vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.405.10">
        <property type="entry name" value="Guanine Nucleotide Dissociation Inhibitor, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.519.10">
        <property type="entry name" value="Guanine Nucleotide Dissociation Inhibitor, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018203">
        <property type="entry name" value="GDP_dissociation_inhibitor"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11787:SF4">
        <property type="entry name" value="CHM, RAB ESCORT PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11787">
        <property type="entry name" value="RAB GDP-DISSOCIATION INHIBITOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00996">
        <property type="entry name" value="GDI"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00891">
        <property type="entry name" value="RABGDIREP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ84005.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="521" mass="58603" checksum="3F27CF4AB9C7987D" modified="2016-11-30" version="1">MEEDLEQTHFDYIILGTGLIESILAGSLARIGKKVLHLDSHQNYGGNWAVFGMRELIQWYLDQKKVVSPSRDTSDRHIDYETNYLANFSQVELNLFPSTSPTDPSRLLSSDQSLLDAYQPDESTRAFLTHLLSSSRSYNLDTTPKLVRSNEELVSILVQSGVGRYLEFKNVEDVYMFDRVQQQLEKVPSSKEDVFTNKSVTLVEKRKLMKCLTFALESTLEDPLLEGTDNMSYGQFLEDRFKITGKLQEAMIYAISLVNHTGKSLLEKIGKNLKRKAMSVSVKAGLEKTRLFVQSMGRFGKGAYLCPLYGGASEIAQAFCRVCAVYGGIYILKQPLEQFLVKEDTCIGVRTADGKELKCERLITGMDYLPSSWSKETESRTVSRAMILSQQLDTSISYSVIPPNTCGNSDPIYGIHQNEKSMACPKGQSVTYLWTVSGERSVLKSAIDLLFKDQDKLLTVSYQHHVRQTEKAELPKNVIVCSGPDASLDFESAIAEAKALFYQCEESHVEFMPEAEENDDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N4H1</accession>
    <name>A0A1C7N4H1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">TauD/TfdA-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_08422</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000646">
        <property type="protein sequence ID" value="OBZ83529.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N4H1"/>
    <dbReference type="STRING" id="101091.A0A1C7N4H1"/>
    <dbReference type="InParanoid" id="A0A1C7N4H1"/>
    <dbReference type="OrthoDB" id="272271at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.130.10">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050411">
        <property type="entry name" value="AlphaKG_dependent_hydroxylases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042098">
        <property type="entry name" value="TauD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003819">
        <property type="entry name" value="TauD/TfdA-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10696:SF54">
        <property type="entry name" value="FAMILY OXIDOREDUCTASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_4G13850)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10696">
        <property type="entry name" value="GAMMA-BUTYROBETAINE HYDROXYLASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02668">
        <property type="entry name" value="TauD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TauD/TfdA-like" evidence="2">
        <location>
            <begin position="94"/>
            <end position="345"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02668"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ83529.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="385" mass="44797" checksum="C6202A0B1BEA60AD" modified="2016-11-30" version="1">MPTVQIKNASQPDFTYLPNLKNYKERTARRLSEKQLQKELPDGFPEQLDGPKLWKGSDYEGKESEWVYELTKEELQEIDNAVHKFEDTEKPFSEISKDTFPLPYFGPKVKELVEEEVVDGRGFIVIRGINPDKYTRAQNIIAYTGVSAYVGKRGLQGRHVLAHIKDLVNEKGLEEIKAPAYTNDHQVYHTDAGDIISLYALGVAEEGGKSRIASSWTVYNELAKTRPDLIHTLSQDWPFQLDLHNDERAYLLRPLLYYVDNKLIIQYARRNFTGFGKNPRREDIPPITEAQAEALDALHYTAEKYNLGIDFQKGDIQYINNLSIFHARDGYVDSEKNTRHLLRHWLHPENAWKIPHQLEDNWNKIYHEEREEIFPVEATIRIFNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N508</accession>
    <name>A0A1C7N508_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Reverse transcriptase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_07783</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000546">
        <property type="protein sequence ID" value="OBZ84170.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N508"/>
    <dbReference type="InParanoid" id="A0A1C7N508"/>
    <dbReference type="OrthoDB" id="2282358at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ84170.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="83" mass="9167" checksum="F74D88EAA3ADC60C" modified="2016-11-30" version="1">MAPIVARVVNLFQKGFLPGKLIGENGLLVHLIAQQAQYQPSTGIGLLLDQKKACDKVLDIYLIQVLHAFCFPVVVIECIEFDT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N6Y9</accession>
    <name>A0A1C7N6Y9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_07059</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000458">
        <property type="protein sequence ID" value="OBZ84893.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N6Y9"/>
    <dbReference type="STRING" id="101091.A0A1C7N6Y9"/>
    <dbReference type="InParanoid" id="A0A1C7N6Y9"/>
    <dbReference type="OrthoDB" id="3170343at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="32"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="93"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="127"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="95"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="127"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="167"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="212"/>
            <end position="221"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ84893.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="336" mass="33224" checksum="3DFB14A8C17920AE" modified="2016-11-30" version="1">MSAAHNTQPSTLASTGVTNDATRQLNENHGIAATGLNGPAVGPTGGHASLGGNTHPNAEHIRHQDAEHAIHAGPGGHHTSGPLSGQDAIRHDVAGLGGQGATGRGAAGSGVTGADAAAATTTKAGLGAASNAHPTSHMGTTGTHTGAGTHPSAYTGNDARPDEIHPTAHTGAHTGAHTGAHTGAHTGAHTGAHTGDHTHTQPTTGVTGSGATGTSAIPSSSLNNDTHVHHDNSKPSAPLGDHGASLHSKNNGGVPNHQDGQRHAGEPQVGPTLKTHNNEPHTVDATTGHHPTTAGDMEHKPSAGEKIKGNLEKMAGKITGNEAKVIKGDNIAHGRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N7P6</accession>
    <name>A0A1C7N7P6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Methylenetetrahydrofolate dehydrogenase [NAD(+)]</fullName>
            <ecNumber evidence="11">1.5.1.15</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="primary">mtd1_0</name>
        <name evidence="15" type="ORF">A0J61_07294</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Catalyzes oxidation of cytoplasmic one-carbon units for purine biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.5.1.15" evidence="11"/>
    <dbReference type="EMBL" id="LUGH01000485">
        <property type="protein sequence ID" value="OBZ84649.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N7P6"/>
    <dbReference type="FunCoup" id="A0A1C7N7P6">
        <property type="interactions" value="449"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N7P6"/>
    <dbReference type="InParanoid" id="A0A1C7N7P6"/>
    <dbReference type="OrthoDB" id="41403at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004487">
        <property type="term" value="F:methylenetetrahydrofolate dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004488">
        <property type="term" value="F:methylenetetrahydrofolate dehydrogenase (NADP+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006730">
        <property type="term" value="P:one-carbon metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009113">
        <property type="term" value="P:purine nucleobase biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01079">
        <property type="entry name" value="NAD_bind_m-THF_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000255">
        <property type="entry name" value="Methylenetetrahydrofolate dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.10860:FF:000012">
        <property type="entry name" value="Methylenetetrahydrofolate dehydrogenase [NAD(+)]"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10860">
        <property type="entry name" value="Leucine Dehydrogenase, chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046346">
        <property type="entry name" value="Aminoacid_DH-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035812">
        <property type="entry name" value="m-THF_DH_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000672">
        <property type="entry name" value="THF_DH/CycHdrlase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020630">
        <property type="entry name" value="THF_DH/CycHdrlase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020631">
        <property type="entry name" value="THF_DH/CycHdrlase_NAD-bd_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48099">
        <property type="entry name" value="C-1-TETRAHYDROFOLATE SYNTHASE, CYTOPLASMIC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48099:SF3">
        <property type="entry name" value="METHYLENETETRAHYDROFOLATE DEHYDROGENASE [NAD(+)]"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00763">
        <property type="entry name" value="THF_DHG_CYH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02882">
        <property type="entry name" value="THF_DHG_CYH_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00085">
        <property type="entry name" value="THFDHDRGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53223">
        <property type="entry name" value="Aminoacid dehydrogenase-like, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0520">NAD</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-0554">One-carbon metabolism</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tetrahydrofolate dehydrogenase/cyclohydrolase catalytic" evidence="13">
        <location>
            <begin position="13"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="domain" description="Tetrahydrofolate dehydrogenase/cyclohydrolase NAD(P)-binding" evidence="14">
        <location>
            <begin position="145"/>
            <end position="205"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00053076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00061364"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00066980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00074830"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF00763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF02882"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="OBZ84649.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="308" mass="34221" checksum="55AE9BA6AC6B5AE6" modified="2016-11-30" version="1">MSTTTSCKTVLASKVSASFRNQIKADIKERNIHPKLVGFLANEDPAAMKYADWTAKTCAETGVDFELRKVSKMDLEEAITEANQDKAVNGIMIYYPVFGGKQDAYLQSCVSKFKDVEGLCHEFVHNVYHNIRFMDEEETMKCIIPCTPLAIVKILEYIGVYNPVIPYGNRLYGRTIAVVNRSEIVGRPLAAMLSNDGAKVYSIDVNGIQLFTRGTGLSLKSHKVEETEATVEQVVPQCDVVITGVPSANYKMPTHLLKEGVVAINFSSLANFQEDIKQKASIFVPSVGKVTVAMLERNLLRLHDYQSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N8R4</accession>
    <name>A0A1C7N8R4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Heat shock factor protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">hsf1_5</name>
        <name evidence="10" type="ORF">A0J61_06453</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the HSF family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000390">
        <property type="protein sequence ID" value="OBZ85493.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N8R4"/>
    <dbReference type="STRING" id="101091.A0A1C7N8R4"/>
    <dbReference type="InParanoid" id="A0A1C7N8R4"/>
    <dbReference type="OrthoDB" id="60033at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.10:FF:000027">
        <property type="entry name" value="Heat shock transcription factor 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000232">
        <property type="entry name" value="HSF_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10015:SF427">
        <property type="entry name" value="HEAT SHOCK FACTOR PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10015">
        <property type="entry name" value="HEAT SHOCK TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00447">
        <property type="entry name" value="HSF_DNA-bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00056">
        <property type="entry name" value="HSFDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00415">
        <property type="entry name" value="HSF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00434">
        <property type="entry name" value="HSF_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0346">Stress response</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HSF-type DNA-binding" evidence="9">
        <location>
            <begin position="69"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="228"/>
            <end position="258"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006403"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU004020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OBZ85493.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="295" mass="34031" checksum="98AA45A6DE779AC3" modified="2016-11-30" version="1">MDMTLPSKSYFSSVLQPSLTNSSTAKSSTFVHKLYNMVADEHFQHLIAWNYTGASFIVCNIMEFARDVLPKHFKHNNFSSFVRQLNMYGFHKVNKSPRGHRTLAENQIWEFSHNKFLKNHPELLDDIKRKTMESDVVRRETDLQAHLAVLQVSQTDMLQQINHLYDSFNQIYKELHETKQRQQDHQKLVKNVMGYLAHQNGGQLPHEIESKKLALNELDRQSLTPSIFVTSHAPPSSSSEQPILLSQTPSTTQHTPYLETSTARQPISLFDILRSPTPTRATLNRDFHFSTTRNG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N8V4</accession>
    <name>A0A1C7N8V4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">40S ribosomal protein S18</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">RPS18_2</name>
        <name evidence="5" type="ORF">A0J61_06404</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the universal ribosomal protein uS13 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000384">
        <property type="protein sequence ID" value="OBZ85553.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N8V4"/>
    <dbReference type="FunCoup" id="A0A1C7N8V4">
        <property type="interactions" value="586"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N8V4"/>
    <dbReference type="InParanoid" id="A0A1C7N8V4"/>
    <dbReference type="OrthoDB" id="5534642at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015935">
        <property type="term" value="C:small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.50:FF:000002">
        <property type="entry name" value="40S ribosomal protein S18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.910.10">
        <property type="entry name" value="30s ribosomal protein s13, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027437">
        <property type="entry name" value="Rbsml_uS13_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001892">
        <property type="entry name" value="Ribosomal_uS13"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010979">
        <property type="entry name" value="Ribosomal_uS13-like_H2TH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10871">
        <property type="entry name" value="30S RIBOSOMAL PROTEIN S13/40S RIBOSOMAL PROTEIN S18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10871:SF3">
        <property type="entry name" value="SMALL RIBOSOMAL SUBUNIT PROTEIN US13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00416">
        <property type="entry name" value="Ribosomal_S13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002134">
        <property type="entry name" value="Ribosomal_S13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46946">
        <property type="entry name" value="S13-like H2TH domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50159">
        <property type="entry name" value="RIBOSOMAL_S13_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 5" id="KW-0689">Ribosomal protein</keyword>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="128"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003830"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OBZ85553.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="128" mass="14794" checksum="27FBFC0B87962197" modified="2016-11-30" version="1" fragment="single">MSLVVPERTTFQHIIRLLNTNVDGRVKIQIALTSIKGVGRRFANIACKKADVDLTKRAGELSSEELERIVTILQNPAQYKIPNWFLNRQKDIVDGKSSQVISNVLDTKFREDLERLKKIRNHRGLRHY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N963</accession>
    <name>A0A1C7N963_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="12">ATP synthase subunit beta, mitochondrial</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">ATP2_0</name>
        <name evidence="12" type="ORF">A0J61_06788</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>ATP + H2O + 4 H(+)(in) = ADP + phosphate + 5 H(+)(out)</text>
            <dbReference type="Rhea" id="RHEA:57720"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="7.1.2.2"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ATPase alpha/beta chains family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000426">
        <property type="protein sequence ID" value="OBZ85169.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N963"/>
    <dbReference type="STRING" id="101091.A0A1C7N963"/>
    <dbReference type="InParanoid" id="A0A1C7N963"/>
    <dbReference type="OrthoDB" id="14523at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045259">
        <property type="term" value="C:proton-transporting ATP synthase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046933">
        <property type="term" value="F:proton-transporting ATP synthase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042776">
        <property type="term" value="P:proton motive force-driven mitochondrial ATP synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd18115">
        <property type="entry name" value="ATP-synt_F1_beta_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.170">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050053">
        <property type="entry name" value="ATPase_alpha/beta_chains"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004100">
        <property type="entry name" value="ATPase_F1/V1/A1_a/bsu_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036121">
        <property type="entry name" value="ATPase_F1/V1/A1_a/bsu_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15184">
        <property type="entry name" value="ATP SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15184:SF71">
        <property type="entry name" value="ATP SYNTHASE SUBUNIT BETA, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02874">
        <property type="entry name" value="ATP-synt_ab_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50615">
        <property type="entry name" value="N-terminal domain of alpha and beta subunits of F1 ATP synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0066">ATP synthesis</keyword>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0139">CF(1)</keyword>
    <keyword evidence="6" id="KW-0406">Ion transport</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ATPase F1/V1/A1 complex alpha/beta subunit N-terminal" evidence="11">
        <location>
            <begin position="38"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="12">
        <location>
            <position position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023196"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023310"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00048383"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF02874"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="OBZ85169.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="95" mass="10085" checksum="EBADBADFB8AFA355" modified="2016-11-30" version="1" fragment="single">MYISRALGFVARAQTNATSRFAATQARRYASAASAGQIRSVIGAVVDVQFEQDNLPAILNALEVKDHAGGRLVLEVAQHLGENTVRTIAMDGTEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N969</accession>
    <name>A0A1C7N969_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Phospho-2-dehydro-3-deoxyheptonate aldolase</fullName>
            <ecNumber evidence="6">2.5.1.54</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">aroG_1</name>
        <name evidence="8" type="ORF">A0J61_06275</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5 6">
            <text>D-erythrose 4-phosphate + phosphoenolpyruvate + H2O = 7-phospho-2-dehydro-3-deoxy-D-arabino-heptonate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:14717"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:16897"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58394"/>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
            <dbReference type="EC" id="2.5.1.54"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the class-I DAHP synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.54" evidence="6"/>
    <dbReference type="EMBL" id="LUGH01000371">
        <property type="protein sequence ID" value="OBZ85675.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N969"/>
    <dbReference type="STRING" id="101091.A0A1C7N969"/>
    <dbReference type="InParanoid" id="A0A1C7N969"/>
    <dbReference type="OrthoDB" id="4699125at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003849">
        <property type="term" value="F:3-deoxy-7-phosphoheptulonate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008652">
        <property type="term" value="P:amino acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009073">
        <property type="term" value="P:aromatic amino acid family biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.70:FF:000005">
        <property type="entry name" value="Phospho-2-dehydro-3-deoxyheptonate aldolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006218">
        <property type="entry name" value="DAHP1/KDSA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006219">
        <property type="entry name" value="DAHP_synth_1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00034">
        <property type="entry name" value="aroFGH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF009395">
        <property type="entry name" value="PRK12755.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF009396">
        <property type="entry name" value="PRK12756.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21225:SF20">
        <property type="entry name" value="PHOSPHO-2-DEHYDRO-3-DEOXYHEPTONATE ALDOLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21225">
        <property type="entry name" value="PHOSPHO-2-DEHYDRO-3-DEOXYHEPTONATE ALDOLASE DAHP SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00793">
        <property type="entry name" value="DAHP_synth_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001361">
        <property type="entry name" value="DAHP_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51569">
        <property type="entry name" value="Aldolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 6" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="4 6" id="KW-0057">Aromatic amino acid biosynthesis</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="DAHP synthetase I/KDSA" evidence="7">
        <location>
            <begin position="49"/>
            <end position="348"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00047508"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRNR" id="PIRNR001361"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OBZ85675.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="364" mass="39433" checksum="AE00B61B8BC5D79B" modified="2016-11-30" version="1">MSAFSALNELDDKRITNIKPLIPPQILMEDLPLSLKAAATILEGRQGAENIIHGNDDRLLVVVGPCSIHDVKAGLEYAERLIEYAKSAKEDLHIIMRVYFEKPRTTVGWKGLINDPNLNNTYEINKGLRIARKLLLDLNEMGIPAACEFLDTISPQYTGDLVSWGAIGARTTESQIHRELASGLSCPVGFKNGTDGGMRVAIDAIGAASHGHHFLSVTKQGLSAIVQTGGNDSCHVILRGGKSGPNYSAEYISSAAEDLKKSKLSPIVMVDCSHGNSSKDHNRQPVVARDIAAQLANPDETGSYIVGVMIESNLVEGRQNIPSDGPEKLTYGKSITDACINWEDTVQVLDSLREGVRARRAARN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N9I8</accession>
    <name>A0A1C7N9I8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Beclin-1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">BECN1</name>
        <name evidence="5" type="ORF">A0J61_06636</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the beclin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000411">
        <property type="protein sequence ID" value="OBZ85309.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N9I8"/>
    <dbReference type="FunCoup" id="A0A1C7N9I8">
        <property type="interactions" value="313"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N9I8"/>
    <dbReference type="InParanoid" id="A0A1C7N9I8"/>
    <dbReference type="OrthoDB" id="20368at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000407">
        <property type="term" value="C:phagophore assembly site"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034271">
        <property type="term" value="C:phosphatidylinositol 3-kinase complex, class III, type I"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034272">
        <property type="term" value="C:phosphatidylinositol 3-kinase complex, class III, type II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043548">
        <property type="term" value="F:phosphatidylinositol 3-kinase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030674">
        <property type="term" value="F:protein-macromolecule adaptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000045">
        <property type="term" value="P:autophagosome assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006995">
        <property type="term" value="P:cellular response to nitrogen starvation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045324">
        <property type="term" value="P:late endosome to vacuole transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000423">
        <property type="term" value="P:mitophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.418.40">
        <property type="entry name" value="Autophagy protein 6/Beclin 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007243">
        <property type="entry name" value="Atg6/Beclin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038274">
        <property type="entry name" value="Atg6/Beclin_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041691">
        <property type="entry name" value="Atg6/beclin_CC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040455">
        <property type="entry name" value="Atg6_BARA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12768">
        <property type="entry name" value="BECLIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12768:SF4">
        <property type="entry name" value="BECLIN-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04111">
        <property type="entry name" value="APG6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17675">
        <property type="entry name" value="APG6_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Atg6/beclin coiled-coil" evidence="4">
        <location>
            <begin position="148"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="domain" description="Atg6 BARA" evidence="3">
        <location>
            <begin position="279"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="188"/>
            <end position="243"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005965"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF04111"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF17675"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OBZ85309.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="464" mass="53417" checksum="37D3B7F1E18E222A" modified="2016-11-30" version="1">MTFQCQRCGHALRIDDSLTHMDEASADVLLAPLIAEEQLAIQAQKSRPSTTTKTAKALHTRLIGIKSQPAKQPGPSESFVVLTHPETHHSPSTDNTSAIQSSTKILLQATTSEDASWSRDSNNSLSHRLKVANRLFDIMSSKSSVDHPMCQECTDMLLEHLQKQMTDVGRERDCYIDFLKKIKDSRVTAEEEAELTQQVEELVLAEKEAKEELDRWMDEENKLDQELNALSEEMKRLDQQEQIFWEKCNSYQLDLQTFQNERDSINLKYDHDVKQYERLQKTVVYNDAFCISQDGPFGTINGFRLGKLSTHPVEWSEINAAWGQTLLLLYTVANKLRFQFKTYRLVPLGSFSKVQKVNGDVVMDYELYGSGDFGINKMLFLNRKFDHAMVAVLNCLEQLTDFAEERDRATRLPYRINKDKIGELSIRIQFNQLDQWTKALKYMLVNMKYILAFASRFNAIEENT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N9Q7</accession>
    <name>A0A1C7N9Q7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Suppressor of SWI4 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">Ppan</name>
        <name evidence="3" type="ORF">A0J61_06271</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000371">
        <property type="protein sequence ID" value="OBZ85678.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N9Q7"/>
    <dbReference type="FunCoup" id="A0A1C7N9Q7">
        <property type="interactions" value="450"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N9Q7"/>
    <dbReference type="InParanoid" id="A0A1C7N9Q7"/>
    <dbReference type="OrthoDB" id="10261452at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030687">
        <property type="term" value="C:preribosome, large subunit precursor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000027">
        <property type="term" value="P:ribosomal large subunit assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007109">
        <property type="entry name" value="Brix"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045112">
        <property type="entry name" value="PPAN-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12661">
        <property type="entry name" value="PETER PAN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12661:SF5">
        <property type="entry name" value="SUPPRESSOR OF SWI4 1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04427">
        <property type="entry name" value="Brix"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00879">
        <property type="entry name" value="Brix"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52954">
        <property type="entry name" value="Class II aaRS ABD-related"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50833">
        <property type="entry name" value="BRIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Brix" evidence="2">
        <location>
            <begin position="23"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="236"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="297"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="297"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="344"/>
            <end position="393"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ85678.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="393" mass="45362" checksum="B4B4DFA0CEBC3C04" modified="2016-11-30" version="1">MAKRKRKNRTHVAPTEEEMNKIPKSFVMRSGIVGTSVTALVRDVRRVLEPHTASHLRERRSNRLKDFVMVAGQLGVTHFLIFSRTDKNVNLRICRVPRGPTLTFRVVEYALTKDCLALQKNPKTSDVEYRKSPLLVLNNFQQPGKEFKVMTAMLQNMFPSVDIHTMQLSEAKRVLLFNYNDETGMIDVRHYSIGVKATGVSKSIKRVINTNLPNLGDFEDISDYVLREAIVSESDVEDGPDSTVTLPQDYGRNNRKNDQRAVRLHELGPRMTLELTKVENGMCGGEVLYHRYITKTQKEVKESERKRQRKLQEKAARREQQEQNVEKKKAEKEARKQSGKASDDEADEDQKEEEDEDEYDDGEEEFDDMQLDEEDSQEEDDDDDDGTEEEDDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N9X0</accession>
    <name>A0A1C7N9X0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">1-phosphatidylinositol 4-kinase</fullName>
            <ecNumber evidence="2">2.7.1.67</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">pik1_1</name>
        <name evidence="8" type="ORF">A0J61_06071</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol 4-phosphate) + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:19877"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57880"/>
            <dbReference type="ChEBI" id="CHEBI:58178"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.67"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.67" evidence="2"/>
    <dbReference type="EMBL" id="LUGH01000349">
        <property type="protein sequence ID" value="OBZ85881.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N9X0"/>
    <dbReference type="FunCoup" id="A0A1C7N9X0">
        <property type="interactions" value="782"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N9X0"/>
    <dbReference type="InParanoid" id="A0A1C7N9X0"/>
    <dbReference type="OrthoDB" id="10264149at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004430">
        <property type="term" value="F:1-phosphatidylinositol 4-kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046854">
        <property type="term" value="P:phosphatidylinositol phosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048015">
        <property type="term" value="P:phosphatidylinositol-mediated signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05168">
        <property type="entry name" value="PI4Kc_III_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1070.11:FF:000016">
        <property type="entry name" value="PIK1p Phosphatidylinositol 4-kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.1260">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1070.11">
        <property type="entry name" value="Phosphatidylinositol 3-/4-kinase, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1010.10">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021601">
        <property type="entry name" value="Phosphatidylino_kinase_fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015433">
        <property type="entry name" value="PI3/4_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000403">
        <property type="entry name" value="PI3/4_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036940">
        <property type="entry name" value="PI3/4_kinase_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018936">
        <property type="entry name" value="PI3/4_kinase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001263">
        <property type="entry name" value="PI3K_accessory_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057754">
        <property type="entry name" value="PI4-kinase_beta/PIK1_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049160">
        <property type="entry name" value="PI4KB-PIK1_PIK"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10048:SF22">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL 4-KINASE BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10048">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00454">
        <property type="entry name" value="PI3_PI4_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21245">
        <property type="entry name" value="PI4KB-PIK1_PIK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11522">
        <property type="entry name" value="Pik1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00146">
        <property type="entry name" value="PI3Kc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00916">
        <property type="entry name" value="PI3_4_KINASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50290">
        <property type="entry name" value="PI3_4_KINASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51545">
        <property type="entry name" value="PIK_HELICAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 8" id="KW-0418">Kinase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PIK helical" evidence="7">
        <location>
            <begin position="1"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="domain" description="PI3K/PI4K catalytic" evidence="6">
        <location>
            <begin position="716"/>
            <end position="993"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="187"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="303"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="342"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="402"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="550"/>
            <end position="624"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="216"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="343"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="403"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="550"/>
            <end position="569"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="570"/>
            <end position="585"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="588"/>
            <end position="600"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="603"/>
            <end position="620"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001686"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51545"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OBZ85881.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="1030" mass="115616" checksum="3EBF3F614505F361" modified="2016-11-30" version="1" fragment="single">VIMSNALLLRLFTSEFFNSWIAVSYLFRYSDNVGIQHYLCTELKRFPISEIEFFLPQLIHLLIISPSESVALECFMIEMCEKSTHIALMTLWYLQAYLSDLSANPTSPSFQLCKRLLNRAQAIVFSEDATEEDKTTFQKTQKVRENALPALVGMSAMLLGIGQPKMTKPAGRIAIAQGRKVFNLSPSTLDSSERLPLDEPPALSRRNTTDDTQYNSQHQSPSKLSTSSLVHSSSFISTSQPDLPIRHQRKKSNFNLFTHSPSLEDLHRGKAFSVSRYIKTAQHKINRKMIQLSQEVIDQHASSIHHGSPLNPKHPSSSSSSSDGTKKRLANTLSVFDPKLTALGQSSVPTNPSTYSPVPSQYSSSEEAILSYASKQRAHQSSHLSTSLESVNYHEDDRASIFSTSSSSSSSSSSSSTQIQEITAENKMNMESCKTALLRSNYFRSEMQFLLALVDIATRLVIVPKPARMSALQAELTLLNHNLPAEICLPLWCPATVEKPYHHRVVRISPSDAVVLNSAERAPYLLMIEVLDDEMSFEDAGHFYRMRRQQLKKLKKKKKRQQKEQHRKPAPAGAGSGSMSSADMADCLDSKEKQTQHQEEENGTLSAHLSLPLTPTSNKAGGQDDYADRMRTAAVMLAQLQSSTTTNKNTEQIRQKIIKEMVALEEQRMKKMKTEGVGSGVGGGGGEGAGGDMLEDEQRIAWVVNKEDPSAAVLSEDWETKKERLRAASPYGHLPNWRLISVIVKNGSDLRQEQFAIQLIREMQRIWEDTGVNVWVKYYRVLVTSDGSGLIETLKNTISIHSIKKDAYTRGWNQKGAVFTLHDYFEKLYGSPDSDEFIKAQDAFMQSLAGYSIACYLLQIKDRHNGNLLLDDTGHLIHIDFGFMLSNSPGSVSFEMAPFKLSQEYIDLLGGFNGEKFAEYKALMKAAFLAVRKHSENILLLTEMMSKDSKLPCFQNGDLTVAQLRDRFQLHLTEPQAEEFVDRLIMSSCCNVFTRLYDTFQYYSQVSGRGNDNNPMLITNFFNRAFCRCN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N9Y7</accession>
    <name>A0A1C7N9Y7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">alpha-1,2-Mannosidase</fullName>
            <ecNumber evidence="9">3.2.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">MNS3</name>
        <name evidence="11" type="ORF">A0J61_06181</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 7">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 9">Belongs to the glycosyl hydrolase 47 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.-" evidence="9"/>
    <dbReference type="EMBL" id="LUGH01000361">
        <property type="protein sequence ID" value="OBZ85768.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N9Y7"/>
    <dbReference type="STRING" id="101091.A0A1C7N9Y7"/>
    <dbReference type="InParanoid" id="A0A1C7N9Y7"/>
    <dbReference type="OrthoDB" id="8118055at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004571">
        <property type="term" value="F:mannosyl-oligosaccharide 1,2-alpha-mannosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036503">
        <property type="term" value="P:ERAD pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012341">
        <property type="entry name" value="6hp_glycosidase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001382">
        <property type="entry name" value="Glyco_hydro_47"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050749">
        <property type="entry name" value="Glycosyl_Hydrolase_47"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036026">
        <property type="entry name" value="Seven-hairpin_glycosidases"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11742:SF103">
        <property type="entry name" value="ENDOPLASMIC RETICULUM MANNOSIDASE MNL2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11742">
        <property type="entry name" value="MANNOSYL-OLIGOSACCHARIDE ALPHA-1,2-MANNOSIDASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01532">
        <property type="entry name" value="Glyco_hydro_47"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00747">
        <property type="entry name" value="GLYHDRLASE47"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48225">
        <property type="entry name" value="Seven-hairpin glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0106">Calcium</keyword>
    <keyword evidence="5 8" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="9" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="4 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="20"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="6">
        <location>
            <position position="193"/>
        </location>
    </feature>
    <feature type="active site" evidence="6">
        <location>
            <position position="327"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="6">
        <location>
            <position position="436"/>
        </location>
    </feature>
    <feature type="active site" evidence="6">
        <location>
            <position position="525"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="627"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </ligand>
    </feature>
    <feature type="disulfide bond" evidence="8">
        <location>
            <begin position="393"/>
            <end position="422"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007658"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR601382-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR601382-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR601382-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU361193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="OBZ85768.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="648" mass="74458" checksum="9B4B356593F75F17" modified="2016-11-30" version="1">MKNQEVALPYTTRVPKKWRIALAVLSVVLVIGQLWVIAESSTSSIAIPEEIDTILNEQQSLDNSVQKSSTNRSHPKKQSLLEGFGGFLSKLPQLQHDFKKEPTEYTKLRNERRAAIKKSFLHGWSGYKKYALGHDELKPISNKTSDPFGGWGVTMVDALSTLAVMELNNEIQEMLPKALKIKFKVDENISVFETVIRYMGGLISIYELTDRKSEALIQKAEKLGQELLPAFDTPTGLPYHYWNPVKQESEGDVTLIAEVGSVQLEFMMLSQLTGNPIYGEKAQAITDFLDNLDYGHGLYIKGLYPTKLDVSDGRFLDATASFGAMGDSAFEYFLKEYILTDGLVPQYGRMYRQSIESMKRYMLRQVPGYDMLMLSSFDTQHKTHKDVMDHLTCFMPGMLAMGAKTFDQPEDLEIAKGLLETCVFMYRTTKTGLSPESWAIPKTEPYNPLTFNKTKAQLAKSRDWWYDPEMTNPLILQKQNAQNVTTELDDERPPSGYVTNYKLPPVRKRPESLYFGDKQYVLRPETVESLFILYRLTGDQKYQEYGWEIYQAIERWCKTKSAYAAIRNVDIDEDYSKENSNKNEAFDPSFNQIDTMESFLLAETFKYLYLLFSPPELISLDKFVFNTEAHPFVRKQWNWDKILKHKLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-06-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NAE8</accession>
    <name>A0A1C7NAE8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_06345</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000379">
        <property type="protein sequence ID" value="OBZ85606.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NAE8"/>
    <dbReference type="InParanoid" id="A0A1C7NAE8"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ85606.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="68" mass="8115" checksum="C3F859CC481A4837" modified="2016-11-30" version="1">MFAKQPKREQWLPLGDIELNLAHNCTIYKYPIRFNPINIVRSGREAQHKRQDQTAIQTLTQKKSFLYQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NAP9</accession>
    <name>A0A1C7NAP9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_07496</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000508">
        <property type="protein sequence ID" value="OBZ84454.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NAP9"/>
    <dbReference type="InParanoid" id="A0A1C7NAP9"/>
    <dbReference type="OrthoDB" id="10373400at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38926:SF5">
        <property type="entry name" value="F-BOX AND LEUCINE-RICH REPEAT PROTEIN 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38926">
        <property type="entry name" value="F-BOX DOMAIN CONTAINING PROTEIN, EXPRESSED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ84454.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="573" mass="67584" checksum="61EE980BB450D775" modified="2016-11-30" version="1">MLLLFPSEIIDHISQFLTQSEYSQLILVNRACYNRFIIPLHKQIEFDDEFQFGEFLQVSKYHQHIQDLKLRIKYISQASKPNFETSFPIWVSRGYKGKPFYSTSPLLPFRDLKTLTLTDCGDYPTPVDIAAHMPNLTHLTIETMDEFNISVGLLDNILQTCPHLEYLDIAAHVADVPKEAQLVSSQSFDKLKTLALRLTSGPSHHELFNRFYIGFRPVHLWLQYVANRFSKLESLTLEAHSIRKNEPHTSSFYSWFHSQCPFLRYFEWHNVFPDDVFLESLSEQQRQLQQFRLTDQYLIEQYIIGALPPYTYLSNIMNLEIEVPSEMECNVLLAILGKTCPQLKQLEMYQSSTHNKEPLYFNYLLDLFPCLTTVCLRRVALDVKQTETIRQPHPLNKLHLQNCCLSTHVFDYLSPCCLNLQYLVLENIVYRDQEYMAKIHLPYQQLIEVDIQYIRIEPDDFDSFIQLFHIKQSDTSYWHLIKQYDDETGQTLTRQQLNEIDMKEFDTTLSQLRTVWLEPDYQLGRYAASPPSVFGNWDLCKMIEKGYVDFECQSVRSVFINDKPYDDFFLSLW</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NAT0</accession>
    <name>A0A1C7NAT0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_05868</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000330">
        <property type="protein sequence ID" value="OBZ86078.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NAT0"/>
    <dbReference type="InParanoid" id="A0A1C7NAT0"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="18"/>
            <end position="36"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ86078.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="220" mass="25542" checksum="4ECE26EED43B35CD" modified="2016-11-30" version="1">MVSQSHSCQAFSLINYNMFKISVSIASWVALSVLLFRSCSTLQNYLQLQIDHTYFRLSFYINLYIFSQIHSFIIYYLISTSLLIHSIGTVSHIIYCGNSIDSTTCHSLHIPSLQNREDSLNRRQASNRHTILSHCRPSKRKHSILWLLMSHGDHNPSFALDIQNFTTLVIPWTIRWPTLYTILFKLDHLQHSKASLSPLAYLGQRLLNWFSPLSTRWPNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-06-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NB07</accession>
    <name>A0A1C7NB07_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_06132</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000355">
        <property type="protein sequence ID" value="OBZ85826.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NB07"/>
    <dbReference type="InParanoid" id="A0A1C7NB07"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ85826.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="77" mass="8964" checksum="C56EE7F36287742F" modified="2016-11-30" version="1">MKFRNCIDQASARKTRFRASSNSQQLKSLGFEIQQIVFNRFQCQQGSQDVYSDSSIKTKDYTTKHNQNNARLPQNKC</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NB28</accession>
    <name>A0A1C7NB28_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Ubiquitin-conjugating enzyme E2 J1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">UBE2J1</name>
        <name evidence="4" type="ORF">A0J61_05746</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000320">
        <property type="protein sequence ID" value="OBZ86200.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NB28"/>
    <dbReference type="InParanoid" id="A0A1C7NB28"/>
    <dbReference type="OrthoDB" id="1158011at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd23799">
        <property type="entry name" value="UBCc_UBE2J"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.110.10:FF:000086">
        <property type="entry name" value="Ubiquitin-conjugating enzyme E2 J1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.110.10">
        <property type="entry name" value="Ubiquitin Conjugating Enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050113">
        <property type="entry name" value="Ub_conjugating_enzyme"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000608">
        <property type="entry name" value="UBC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016135">
        <property type="entry name" value="UBQ-conjugating_enzyme/RWD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24067">
        <property type="entry name" value="UBIQUITIN-CONJUGATING ENZYME E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00179">
        <property type="entry name" value="UQ_con"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00212">
        <property type="entry name" value="UBCc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54495">
        <property type="entry name" value="UBC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50127">
        <property type="entry name" value="UBC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="1" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="231"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="domain" description="UBC core" evidence="3">
        <location>
            <begin position="12"/>
            <end position="161"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OBZ86200.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="254" mass="29206" checksum="62B50D527624F34D" modified="2016-11-30" version="1">MMNNTKYNLKNPGVKRIMQEAKELAKENNYEYDAHPLEDNIFEWHFTVRGPKDTEFEDGRYHGRILLPTEYPFKPPEIIFLTPNGRFELNTKICXSITGFHPEFWQPAWGIRTALLAVIGFFPTEAKGAIGGLDYTKGERKKLAKKSLDWTCPQCEVNLKDALSDTLPEIDDNDNDRVALPDFKMDYKVEDQSEQDQDIVPIKSTQNPIIQNIQLIPERTVTTPHRPPPPIWLDALIAGLASFVIVLIIRRYIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NB74</accession>
    <name>A0A1C7NB74_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">RING-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">A0J61_05733</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000319">
        <property type="protein sequence ID" value="OBZ86208.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NB74"/>
    <dbReference type="STRING" id="101091.A0A1C7NB74"/>
    <dbReference type="InParanoid" id="A0A1C7NB74"/>
    <dbReference type="OrthoDB" id="8062037at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036503">
        <property type="term" value="P:ERAD pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040176">
        <property type="entry name" value="RNF121/RNF175"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13407:SF0">
        <property type="entry name" value="FI05221P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13407">
        <property type="entry name" value="RNF121 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13639">
        <property type="entry name" value="zf-RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <keyword evidence="6" id="KW-0863">Zinc-finger</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="55"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="81"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="106"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="143"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="170"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="315"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="domain" description="RING-type" evidence="8">
        <location>
            <begin position="227"/>
            <end position="288"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OBZ86208.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="339" mass="38905" checksum="067C222A893B6370" modified="2016-11-30" version="1">MDPNSGQDISFSAAWLEGALTDEQISHLTPEQLENYKLQLDYNKQHKGHEAQHELMAFILLFALFASQFLILWWKKKHYASYQSISLGGLYFFPMLFGIYAGWPRFLVIWTIFSILNGLVLYKATRKPLEAMTPRMVYKWYYVLYNVSFVVGLMGYILMLFVFFGLSELFGFSAGMIQVGVLLLSYGLYFGVLGRDFVEICTDRMAATIGYYNKEGLPNKYLGEGICAVCGHATSVSTGQVALAHEPANRPMFSDDPVHQLTCKHTFHEKCIRGWVMIGKKDICPYCKEKVDLKEFKRNPWDTQQQLYLNLLDGVRYLVVWQPIIFGAVQLAYYIIGLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NB97</accession>
    <name>A0A1C7NB97_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Proteasome subunit alpha type</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">Psma8</name>
        <name evidence="7" type="ORF">A0J61_05702</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="4">The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="4">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 4">Belongs to the peptidase T1A family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000316">
        <property type="protein sequence ID" value="OBZ86238.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NB97"/>
    <dbReference type="FunCoup" id="A0A1C7NB97">
        <property type="interactions" value="380"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NB97"/>
    <dbReference type="InParanoid" id="A0A1C7NB97"/>
    <dbReference type="OrthoDB" id="431557at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042175">
        <property type="term" value="C:nuclear outer membrane-endoplasmic reticulum membrane network"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034399">
        <property type="term" value="C:nuclear periphery"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019773">
        <property type="term" value="C:proteasome core complex, alpha-subunit complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034515">
        <property type="term" value="C:proteasome storage granule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010499">
        <property type="term" value="P:proteasomal ubiquitin-independent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043161">
        <property type="term" value="P:proteasome-mediated ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd03755">
        <property type="entry name" value="proteasome_alpha_type_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.20.10:FF:000004">
        <property type="entry name" value="Proteasome subunit alpha type-4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.10">
        <property type="entry name" value="Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050115">
        <property type="entry name" value="Proteasome_alpha"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023332">
        <property type="entry name" value="Proteasome_alpha-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000426">
        <property type="entry name" value="Proteasome_asu_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001353">
        <property type="entry name" value="Proteasome_sua/b"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003075">
        <property type="entry name" value="PRK03996.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11599">
        <property type="entry name" value="PROTEASOME SUBUNIT ALPHA/BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00227">
        <property type="entry name" value="Proteasome"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10584">
        <property type="entry name" value="Proteasome_A_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00948">
        <property type="entry name" value="Proteasome_A_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="N-terminal nucleophile aminohydrolases (Ntn hydrolases)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00388">
        <property type="entry name" value="PROTEASOME_ALPHA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51475">
        <property type="entry name" value="PROTEASOME_ALPHA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="2 3 4" id="KW-0647">Proteasome</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Proteasome alpha-type subunits" evidence="6">
        <location>
            <begin position="4"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="231"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="231"/>
            <end position="240"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00808"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS00388"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OBZ86238.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="251" mass="27881" checksum="3FB5D0D6FFB20D76" modified="2016-11-30" version="1">MSGYDRALTVFSPDGHLFQVEYASEAVRKGTCAVGVRGKNVVVLGVEKKSVLKLQDPRTVRKICMLDDHICMAFAGLTADARVLVNKARIECQSHRLTVEDPASVEYITRHIAQVQQKYTQSGGVRPFGISTLIVGFDNKEPRLYMTEPSGIYTAWKANAIGRSSKTVREFLEKNYNEEMDQKETIKLAIKSLLEVVQTGAKNIEIAVMTSDSVVKHLEQDEVESVVAEIEKEKEEEAEKKKKPTAASSSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NBM6</accession>
    <name>A0A1C7NBM6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Serrate RNA effector molecule</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">Ars2</name>
        <name evidence="7" type="ORF">A0J61_05574</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ARS2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000304">
        <property type="protein sequence ID" value="OBZ86378.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NBM6"/>
    <dbReference type="FunCoup" id="A0A1C7NBM6">
        <property type="interactions" value="20"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NBM6"/>
    <dbReference type="InParanoid" id="A0A1C7NBM6"/>
    <dbReference type="OrthoDB" id="342064at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016604">
        <property type="term" value="C:nuclear body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031047">
        <property type="term" value="P:regulatory ncRNA-mediated gene silencing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016070">
        <property type="term" value="P:RNA metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025239">
        <property type="entry name" value="DUF4187"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039727">
        <property type="entry name" value="SE/Ars2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007042">
        <property type="entry name" value="SERRATE/Ars2_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021933">
        <property type="entry name" value="SERRATE/Ars2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13165">
        <property type="entry name" value="ARSENITE-RESISTANCE PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13165:SF0">
        <property type="entry name" value="SERRATE RNA EFFECTOR MOLECULE HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04959">
        <property type="entry name" value="ARS2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13821">
        <property type="entry name" value="DUF4187"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12066">
        <property type="entry name" value="SERRATE_Ars2_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01173">
        <property type="entry name" value="DUF4187"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="6">
        <location>
            <begin position="563"/>
            <end position="593"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="476"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="11"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="74"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="480"/>
            <end position="494"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005407"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OBZ86378.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="724" mass="84095" checksum="22CC8BD9FEA75AE4" modified="2016-11-30" version="1">MAYNEWSDDETVSRSHGRDKFRHERSLERDRYAEDYDRYDRKKRGRRSPTPPEDRRHKRRPSYSPPPMRNYGRSNRDYRNDPETDHYIPNYERDGYVPGPRYGSKPEAPAGGGNTLSHPFVNNNNSPNLGGYPMIDMMNPQMVNQNWNGGVGRFPLVDPAQLDYLVPFKQFSEYTKRTSSRRVDDEDMQKRFAHYKEKFAARQLAQFFNANKDKEWFQEKYHPTISRPRQEDVKERRRRYLNEFLQELENGQYDEVCFDKDDSPTTHEEEEQIPEAIETNEEDDENVEFESRLVIKTVPPTIAREKILEMCSKVEGFEYLALSEPGPNKKFHRIGWINFKPGTDIKKAFEELDSQKVDDFVFHLAMNRKNAPQNRVPRVAPDIANTPERLQKDLEQAKELALALEAMLGEDTPEGLKAVESRALRSDESTKKTLDMIIAYLRRVHMYCYYCALECDSLEELSRKCFEPHCRTTTTLADKSPTDSKQAAKAERGGKHSIRVIRNSTNLFHFQVQQWAKNLDQRISLKIHTPDDREIKRLGGRIFQTEVDDFVKEHVLKEHESKFKCQVTGCSKAFKGFDYVEKHILSKHPEEIDRIRNEVEYYNNYVLDPNHIVPNSTPNNNQNMMPLQAMSFHPQQFVLAPNMRMAPPTAAMAGTPWDQIPRIGFGANANDAWGASGRKQSRPTSSSAALMMDLDDSMPKDPRQMKSYVDLDAPAEGDSNISFY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NBY2</accession>
    <name>A0A1C7NBY2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_05305</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000283">
        <property type="protein sequence ID" value="OBZ86637.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NBY2"/>
    <dbReference type="InParanoid" id="A0A1C7NBY2"/>
    <dbReference type="OrthoDB" id="2282689at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="62"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="118"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="340"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="118"/>
            <end position="133"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ86637.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="405" mass="45077" checksum="BF7F2F3F15E84C70" modified="2016-11-30" version="1">MMHPLEQQNDNLGLSLHSDSLLTLQAESLFKSDSNEDSEEEDAKLDRISDILSSLIQEANEAVNQSDVKVSPPKPLGSIPMVRKLSSSSSSEQRQHQKRRVSRIAVRPLSYPSAIKRSAAVSSSSYSNPSNTNHTVCYPKHNHQVVSLHTRRPSSSSSFSHAVQVHQQGATEDVLMESFKRLDTSLAMIDSLSRDLAPPETNKPVSADQSISFVSAKSSNRNQINTIMTITNNTKNSLSLDSRLSALLLLPLLHVPHALISIAFESISNNDHHAPNNSLSGAFIWAILFAITNLVVDKALISPITIKNTPSENSDHKIELKEPPCTFAPSVRLNTTNTRMRRKSVNSKRIATHRRKHSFHQKQHKFFHDNTPFSTSPMQSSSFTSFVLPHRTLSNQPNLSRRYSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-06-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NC48</accession>
    <name>A0A1C7NC48_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_05397</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000290">
        <property type="protein sequence ID" value="OBZ86550.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NC48"/>
    <dbReference type="InParanoid" id="A0A1C7NC48"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ86550.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="89" mass="10369" checksum="88800CED9167F80D" modified="2016-11-30" version="1">MNVFDTIYKVLLFGFNEPDSETALKVLNSKVKEHLDRRKDVGRDSVNEREGVEKQQTLLLESESEIERDRLMLTRSWEPHHVLCTGVVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NCZ3</accession>
    <name>A0A1C7NCZ3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Beta,beta-carotene 9',10'-oxygenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">Bco2</name>
        <name evidence="7" type="ORF">A0J61_04946</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
        <text evidence="5">Binds 1 Fe(2+) ion per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the carotenoid oxygenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000254">
        <property type="protein sequence ID" value="OBZ87002.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NCZ3"/>
    <dbReference type="STRING" id="101091.A0A1C7NCZ3"/>
    <dbReference type="InParanoid" id="A0A1C7NCZ3"/>
    <dbReference type="OrthoDB" id="407010at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010436">
        <property type="term" value="F:carotenoid dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016121">
        <property type="term" value="P:carotene catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004294">
        <property type="entry name" value="Carotenoid_Oase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10543">
        <property type="entry name" value="BETA-CAROTENE DIOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10543:SF24">
        <property type="entry name" value="CAROTENOID ISOMEROOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03055">
        <property type="entry name" value="RPE65"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0408">Iron</keyword>
    <keyword evidence="2 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="27"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="39"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="266"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR604294-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OBZ87002.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="636" mass="71716" checksum="902A7794AA8F8ABA" modified="2016-11-30" version="1">MEDTNDNNNVPEKVEEVALIENAIEEHPLQPESVEDSTLLDNQGRPNLSPSESSISQLEQPKEQILDTDTSHIKGFYNVADSSDILDLTVEGKLPEWLLGEHYTVGPGVYDVRYSRKIEVEGVLQSATSTFTLGHWFDALPLVNRFDLDGQRNTVTYRHRLVNKRLIEKIRDHHGYAPQYPAGLFKTNSNQTMLIKFLNNGKKPKPDRVPCGQRITTQLPGIEGRLFCQNLANHIQELDPIDLKPMRVETWDEVNPEFKGYSASPHGQYDPNTGEYINFTMEIGYRSTKYHFFSISEADPKGSTIATIWNAPTGWTQQFCLTPNYIVMIIHPMLANTGAVKFSWSESILDSFDFYPSEPTLFYVISRQAKDVIACYRSNASFSFNQANAFEDIHGNVVVDLASYQDDAIAHQLSTEMLRQPEKMGRLAAAELRRYTLNQPQHDAHQTYVANNSFIPSAVSITSRVGTVWNYVTGSTNLPENAIGSSGWHAWMPVVDYEKLTNVTLELPTINPDYKMKPYSFVYGLAFKDNLSSLAVPEGKLWDSIVKLDINDRKVVASWHQEHCYPSEAQFIPKSGDKSNQEEDAGALVSIVMDSARATSFLLVLDAKDLQVLAKVELNKLIPLSFGRGCYKPRML</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NDE7</accession>
    <name>A0A1C7NDE7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Sialate O-acetylesterase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_05162</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000271">
        <property type="protein sequence ID" value="OBZ86789.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NDE7"/>
    <dbReference type="InParanoid" id="A0A1C7NDE7"/>
    <dbReference type="OrthoDB" id="42638at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001681">
        <property type="term" value="F:sialate O-acetylesterase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1110">
        <property type="entry name" value="SGNH hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005181">
        <property type="entry name" value="SASA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036514">
        <property type="entry name" value="SGNH_hydro_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039329">
        <property type="entry name" value="SIAE"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22901">
        <property type="entry name" value="SIALATE O-ACETYLESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22901:SF0">
        <property type="entry name" value="SIALATE O-ACETYLESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03629">
        <property type="entry name" value="SASA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52266">
        <property type="entry name" value="SGNH hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Sialate O-acetylesterase" evidence="2">
        <location>
            <begin position="1"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03629"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ86789.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="230" mass="25617" checksum="561F868BB12B01E5" modified="2016-11-30" version="1" fragment="single">LWYQGESDAFDSARAKIYGKLFQAWVSQLREDLSQPNLPVVFVQIGPYNLESSEHRNNWKKIQAAQFEMFGQSPYTAGVASMDAMLDSSRDLSASGLSLVGRRLALAADKAMKGEGASATPLPLTAYRQRLSWNHEWHSLDVMSIYLKFKHLSSPWKLEPDQPVVGFSFGSFKTPITKAFVADAKKGSVRLYLHRVIEGPLVIHYGMQPGRANLVTQDGRALPAFANFPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NDI0</accession>
    <name>A0A1C7NDI0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="1">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">oca2_2</name>
        <name evidence="12" type="ORF">A0J61_05350</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="1"/>
    <dbReference type="EMBL" id="LUGH01000286">
        <property type="protein sequence ID" value="OBZ86606.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NDI0"/>
    <dbReference type="FunCoup" id="A0A1C7NDI0">
        <property type="interactions" value="77"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NDI0"/>
    <dbReference type="InParanoid" id="A0A1C7NDI0"/>
    <dbReference type="OrthoDB" id="6513151at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd13994">
        <property type="entry name" value="STKc_HAL4_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24343">
        <property type="entry name" value="SERINE/THREONINE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24343:SF137">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE HRK1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 12" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="11">
        <location>
            <begin position="225"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="58"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="188"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="511"/>
            <end position="566"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="16"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="58"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="188"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="557"/>
            <end position="566"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="254"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="OBZ86606.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="566" mass="63962" checksum="BF0F312418CFBCD5" modified="2016-11-30" version="1">MHLVNQRYDVVTPERSVPSSPSLSPAVVTPTVATSKPQRRSWDPSAVDLSELTKLLAKNSTKNRPRSQLFQSSKPPSPTLSTSSAEPTFCTDANATAVPILSQQQSRPVLSHRPASTCSTPSQFIFKKPEYNETYHQTHFHRNQPPPLIPSSSLTINTSPPSPMAPQDRKDLFLAWSDLRRFFVNTQQAAGSVSPSSPTPSNHSQEERPDTFANQFRQDIGGRYGTWGKYIGKGAGGSVRLIRRSADQKTFAVKQFRKRLPHESEKDYIKKVTAEFCIGSTLHHPNIIETLDIIQEDDTFYEIMEYAPNDLFNVVMSGMMSREEIACCWRQLLYGIEYLQSMGIAHRDIKLDNLVLDHLGILKIIDFGCSTVYRYPFEDTITLTKGVYGSDPYIAPEQYTQPTYDPRLSDIWSCGIVFLCMTIRRFPWRIPRLTDPSFRAYATNHNQQQFRLLKLLPREARPVMAGILDIDPNRRSNLETILADKWIQQIDVCQVHEPGKRHVHHVLSIPPSSHGRDNLVVVTPEPPGVVAEKEKRKRSSRPASPSIPQKAVMNAAVQAQQKQQSH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NDI9</accession>
    <name>A0A1C7NDI9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 9">Isocitrate lyase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">ACU-7</name>
        <name evidence="13" type="ORF">A0J61_05120</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>(2S,3R)-3-hydroxybutane-1,2,3-tricarboxylate = pyruvate + succinate</text>
            <dbReference type="Rhea" id="RHEA:16809"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:30031"/>
            <dbReference type="ChEBI" id="CHEBI:57429"/>
            <dbReference type="EC" id="4.1.3.30"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>D-threo-isocitrate = glyoxylate + succinate</text>
            <dbReference type="Rhea" id="RHEA:13245"/>
            <dbReference type="ChEBI" id="CHEBI:15562"/>
            <dbReference type="ChEBI" id="CHEBI:30031"/>
            <dbReference type="ChEBI" id="CHEBI:36655"/>
            <dbReference type="EC" id="4.1.3.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="12">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="12">Can also use Mn(2+) ion.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2">Carbohydrate metabolism; glyoxylate cycle; (S)-malate from isocitrate: step 1/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 9">Belongs to the isocitrate lyase/PEP mutase superfamily. Isocitrate lyase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000268">
        <property type="protein sequence ID" value="OBZ86829.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NDI9"/>
    <dbReference type="FunCoup" id="A0A1C7NDI9">
        <property type="interactions" value="97"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NDI9"/>
    <dbReference type="InParanoid" id="A0A1C7NDI9"/>
    <dbReference type="OrthoDB" id="4078635at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004451">
        <property type="term" value="F:isocitrate lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046421">
        <property type="term" value="F:methylisocitrate lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006097">
        <property type="term" value="P:glyoxylate cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00377">
        <property type="entry name" value="ICL_PEPM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.850:FF:000001">
        <property type="entry name" value="Isocitrate lyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.850">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.60">
        <property type="entry name" value="Phosphoenolpyruvate-binding domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039556">
        <property type="entry name" value="ICL/PEPM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006254">
        <property type="entry name" value="Isocitrate_lyase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018523">
        <property type="entry name" value="Isocitrate_lyase_ph_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015813">
        <property type="entry name" value="Pyrv/PenolPyrv_kinase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040442">
        <property type="entry name" value="Pyrv_kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01346">
        <property type="entry name" value="isocit_lyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21631:SF3">
        <property type="entry name" value="BIFUNCTIONAL GLYOXYLATE CYCLE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21631">
        <property type="entry name" value="ISOCITRATE LYASE/MALATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00463">
        <property type="entry name" value="ICL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001362">
        <property type="entry name" value="Isocit_lyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51621">
        <property type="entry name" value="Phosphoenolpyruvate/pyruvate domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00161">
        <property type="entry name" value="ISOCITRATE_LYASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0329">Glyoxylate bypass</keyword>
    <keyword evidence="7 9 13" id="KW-0456">Lyase</keyword>
    <keyword evidence="12" id="KW-0460">Magnesium</keyword>
    <keyword evidence="12" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0816">Tricarboxylic acid cycle</keyword>
    <feature type="active site" description="Proton acceptor" evidence="10">
        <location>
            <position position="205"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="96"/>
            <end position="98"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="167"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="206"/>
            <end position="207"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="242"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="419"/>
            <end position="423"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="454"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001050"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005704"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00017446"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022435"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRNR" id="PIRNR001362"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR001362-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR001362-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR001362-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="OBZ86829.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="535" mass="59068" checksum="A443FD41000A7F79" modified="2016-11-30" version="1">MTVDYEQKLFLEEVEKVKQWWASPRFANVKRPYTAEAIVSKRGYFPIQYRSDVQAKKVWKLLQNHKANGTTSHTFGALDPVQVTQMAPHLETVYVSGWQCSSTASTSNEPGPDLADYPMDTVPNKVEHLFFAQLFHDRKQREARLAMSPEERAKTPAIDYLRPIIADGDTGHGGITAVMKLAKMFVERGAAGMHVEDQSPSTKKCGHMAGKVLVPIGEHINRLVAIRVQYDIMGVENLIVARSDAEAATLITSNIDPRDHEFIVGTTNPQAGALATLMNEAEAAGKTGAALQAVEDEWIAKAGLKRFGTAVADELQKAGKASAAQEFLNKIHYKSNAEARAIAKNEYGIDIFWDWDLPRVREGLYRYEGGTEAATSRAVAFAPFADMLWMETKKPILSQAKQFSEGVLSVYPKALLCYNLSPSFNWDAAGLNDNAMQSYIHDLAKLGFVWQFITLGGLHANALATATFAKAYKEYGMLGYVSQVQRREREHGVDVLQHQKWSGANYVDELIKVVTGGVAATAAMGKGVTEDQFKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NDW6</accession>
    <name>A0A1C7NDW6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">peptidylprolyl isomerase</fullName>
            <ecNumber evidence="3">5.2.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">cyp15</name>
        <name evidence="11" type="ORF">A0J61_04698</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 13">
            <text>[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)</text>
            <dbReference type="Rhea" id="RHEA:16237"/>
            <dbReference type="Rhea" id="RHEA-COMP:10747"/>
            <dbReference type="Rhea" id="RHEA-COMP:10748"/>
            <dbReference type="ChEBI" id="CHEBI:83833"/>
            <dbReference type="ChEBI" id="CHEBI:83834"/>
            <dbReference type="EC" id="5.2.1.8"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the cyclophilin-type PPIase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.2.1.8" evidence="3"/>
    <dbReference type="EMBL" id="LUGH01000235">
        <property type="protein sequence ID" value="OBZ87258.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NDW6"/>
    <dbReference type="FunCoup" id="A0A1C7NDW6">
        <property type="interactions" value="879"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NDW6"/>
    <dbReference type="InParanoid" id="A0A1C7NDW6"/>
    <dbReference type="OrthoDB" id="10264753at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01927">
        <property type="entry name" value="cyclophilin_WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.100.10:FF:000003">
        <property type="entry name" value="Peptidylprolyl isomerase domain and WD repeat-containing 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.10:FF:000450">
        <property type="entry name" value="Peptidylprolyl isomerase domain and WD-repeat protein 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.100.10">
        <property type="entry name" value="Cyclophilin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029000">
        <property type="entry name" value="Cyclophilin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020892">
        <property type="entry name" value="Cyclophilin-type_PPIase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002130">
        <property type="entry name" value="Cyclophilin-type_PPIase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044666">
        <property type="entry name" value="Cyclophilin_A-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45625">
        <property type="entry name" value="PEPTIDYL-PROLYL CIS-TRANS ISOMERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45625:SF4">
        <property type="entry name" value="PEPTIDYLPROLYL ISOMERASE DOMAIN AND WD REPEAT-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00160">
        <property type="entry name" value="Pro_isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00153">
        <property type="entry name" value="CSAPPISMRASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50891">
        <property type="entry name" value="Cyclophilin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00170">
        <property type="entry name" value="CSA_PPIASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50072">
        <property type="entry name" value="CSA_PPIASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 11" id="KW-0413">Isomerase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="6" id="KW-0697">Rotamase</keyword>
    <keyword evidence="4 8" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="8">
        <location>
            <begin position="130"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="domain" description="PPIase cyclophilin-type" evidence="10">
        <location>
            <begin position="514"/>
            <end position="657"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007365"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="OBZ87258.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="658" mass="74721" checksum="163D7500405741F7" modified="2016-11-30" version="1">MADDLNTNNKRPLEDDPSVQEEESGKSIFILKVVGSNAYHITDDDIGPMLPPTSSSTEEVPKKKKRTLAYEKLYLEHLPNADMYEKSYMHRDILSQVAVTKNDFVVTTSADGHLKFWKKTASGIEFVKHYKSHLSSIVDISLSADGELLATISDDMSMKVYDITNFDMINMIKLKYKPKAVCWIHQKGQAQALVAVSFTQSYTFSSEAENPTIHIYDGRSDGKPLHSLPKMHSKPVHLIEFNWRFNTVVSVDTLGMIEYWTPEEPFGLPTHDLEFEMKSQTDLYEFRKKKSVPTCLTFSPDGLNFVTMSFPDRQVRLFKFLSGKKYREYDESLHVISEMQQAGTSVFKLDDMEFGRRLAVEKELEKSYQAKFVNAVFDETGHFIIYGALLGIKVVNTLTNKVVRIIGKSESNRFVNMGLYQGAPRKKGVYTLAMAASDNAALKESQELDPTLFCTAFNKNRFYMMTRREPFEHGQKGERDVFNEKPSREEQTVAATQERKQVLGTSAIIRTTSGDIHMRLFPDAAPKAVENFVTHSKNGYYDNLIFHRIIKGFMIQTGCPFGDGTGGESIWGDDFEDEFSREFRHDRPYTVSMANAGPNTNGSQFFITVAPATWLDNKHSVFGRVTAGMDVVHSIENAKVDKTSKPYDDIKIINIEIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NEJ2</accession>
    <name>A0A1C7NEJ2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">12-oxophytodienoate reductase 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">OPR1_5</name>
        <name evidence="2" type="ORF">A0J61_04442</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000217">
        <property type="protein sequence ID" value="OBZ87507.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NEJ2"/>
    <dbReference type="FunCoup" id="A0A1C7NEJ2">
        <property type="interactions" value="288"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NEJ2"/>
    <dbReference type="InParanoid" id="A0A1C7NEJ2"/>
    <dbReference type="OrthoDB" id="276546at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02933">
        <property type="entry name" value="OYE_like_FMN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.70:FF:000138">
        <property type="entry name" value="NADPH dehydrogenase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001155">
        <property type="entry name" value="OxRdtase_FMN_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045247">
        <property type="entry name" value="Oye-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22893">
        <property type="entry name" value="NADH OXIDOREDUCTASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22893:SF91">
        <property type="entry name" value="NADPH DEHYDROGENASE 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00724">
        <property type="entry name" value="Oxidored_FMN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51395">
        <property type="entry name" value="FMN-linked oxidoreductases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NADH:flavin oxidoreductase/NADH oxidase N-terminal" evidence="1">
        <location>
            <begin position="8"/>
            <end position="342"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00724"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ87507.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="367" mass="40948" checksum="3FCF01251288274B" modified="2016-11-30" version="1">MSAANSALFAPIKVGKNELKHRVVLAPLTRFRATPKAVPTDLQVEHYKQRATEGGLLITEATYINRLAGSYPQAPGIYTKEQIEAWKKVTEAVHEKKGVIYLQLWHVGRAGLKSFNPNQEQIVSASDIPISGKNMFGVDHEVPRPLTVDEIKAIVQDYRQAALNAIEAGFDGVEIHGANGYLIDQFINSGTNKRTDQYGGSIENRARFAFEVIDAIAGAIGADRTAIRFSPGGSFQDMHDDTVVETWSYLTSQLQQNHPDLAYLHFIEARANFLNDETNSADTLEPYRQIWKGPFVAASGFSTNIPHAIETANKTGNLIAFGRAFIANPDLPERIRNGWELNKYDRSTFYTYDPVGYNDYPFYDTKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NEK0</accession>
    <name>A0A1C7NEK0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_04770</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000240">
        <property type="protein sequence ID" value="OBZ87179.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NEK0"/>
    <dbReference type="InParanoid" id="A0A1C7NEK0"/>
    <dbReference type="OrthoDB" id="2237231at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="unsure residue" description="I or L" evidence="1">
        <location>
            <position position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ87179.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="318" mass="36300" checksum="5A65B887A3F612BF" modified="2016-11-30" version="1">MMDHYINTSIYLDQSVEAIEMHQQGFFSDNDGMEMEDDHVMEEMAEEDFSILATDANDQDWTEEEILGFEPEASTEVVELDEVDQLAETFASTKVSHSAISKILYMMVTKLNNKYTTQEGTEFVMDCLSQVFEETGGSFRFPKRVPTFANRNXLLNCSNEGIKAFVVCPKCHALHESGNHGVQRDKPTANAVWVPTHASFYCTGNLLALNNRVPPAMSLQMEYAYCSVKATLGNFLMRREFAEQLAQWKHRRTVDGHFLDLQDASMFNQFKALPTDAMPFAYESNYNLQLALNMDWFSPFEHSYSVGCIYMSILNLPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NFH1</accession>
    <name>A0A1C7NFH1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Actin-related protein 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">arpC</name>
        <name evidence="8" type="ORF">A0J61_04097</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the actin family. ARP3 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000193">
        <property type="protein sequence ID" value="OBZ87845.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NFH1"/>
    <dbReference type="FunCoup" id="A0A1C7NFH1">
        <property type="interactions" value="276"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NFH1"/>
    <dbReference type="InParanoid" id="A0A1C7NFH1"/>
    <dbReference type="OrthoDB" id="421448at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030479">
        <property type="term" value="C:actin cortical patch"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005885">
        <property type="term" value="C:Arp2/3 protein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051285">
        <property type="term" value="C:cell cortex of cell tip"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032153">
        <property type="term" value="C:cell division site"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051015">
        <property type="term" value="F:actin filament binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044396">
        <property type="term" value="P:actin cortical patch organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030041">
        <property type="term" value="P:actin filament polymerization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034314">
        <property type="term" value="P:Arp2/3 complex-mediated actin nucleation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd10221">
        <property type="entry name" value="ASKHA_NBD_Arp3-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.40:FF:000029">
        <property type="entry name" value="Actin-related protein 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.640.10:FF:000006">
        <property type="entry name" value="Actin-related protein 3 (ARP3)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.640.10">
        <property type="entry name" value="Actin, Chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004000">
        <property type="entry name" value="Actin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020902">
        <property type="entry name" value="Actin/actin-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11937">
        <property type="entry name" value="ACTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00022">
        <property type="entry name" value="Actin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00268">
        <property type="entry name" value="ACTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01132">
        <property type="entry name" value="ACTINS_ACT_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0009">Actin-binding</keyword>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006681"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OBZ87845.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="430" mass="48367" checksum="E781099C6F456378" modified="2016-11-30" version="1">MSRLPVVVMDNGTGYTKLGFSGNSEPSFVFPTAISTRESPTSTGRPGVPSKPSFLSNNLASKRGIEDLDFYIGDEAIAQAKTMALNYPIRHGQINNWDHMERFWEQSIFKYLRCEPEDHYFLLTEPPMNSPENREMTAEIMFESFNVQGLYIAVQAVLALAASWTSSKVSEQTLTGTVVDSGDGVTHVIPVAEGYVIASSIKSVPIAGSDITSFVQNLLRERGETSIPPEDSFRIAQAIKEDYSYVCPDIVKEFKKYEQEPSKYFKQYDGIHSVTGKSYSVDIGFERFLAPEIFFNPEIASSDFLTPLPEIVDTVIQTSPIDARRGLYKNIVLSGGSTMFKGFDKRLQRDIKRTVDKRIQDSELRSRSEMKATPMEVNVISHKKQRHAVWFGGALLASTAEFYNTCHTKAEYDEYGPSICRHNRVFRQSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NGD6</accession>
    <name>A0A1C7NGD6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">40S ribosomal protein S7</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">rps7_1</name>
        <name evidence="5" type="ORF">A0J61_03843</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the eukaryotic ribosomal protein eS7 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000175">
        <property type="protein sequence ID" value="OBZ88095.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NGD6"/>
    <dbReference type="FunCoup" id="A0A1C7NGD6">
        <property type="interactions" value="576"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NGD6"/>
    <dbReference type="InParanoid" id="A0A1C7NGD6"/>
    <dbReference type="OrthoDB" id="1724687at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030686">
        <property type="term" value="C:90S preribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022627">
        <property type="term" value="C:cytosolic small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032040">
        <property type="term" value="C:small-subunit processome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042274">
        <property type="term" value="P:ribosomal small subunit biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000554">
        <property type="entry name" value="Ribosomal_eS7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047861">
        <property type="entry name" value="Ribosomal_eS7_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11278">
        <property type="entry name" value="40S RIBOSOMAL PROTEIN S7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11278:SF0">
        <property type="entry name" value="SMALL RIBOSOMAL SUBUNIT PROTEIN ES7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01251">
        <property type="entry name" value="Ribosomal_S7e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00948">
        <property type="entry name" value="RIBOSOMAL_S7E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 5" id="KW-0689">Ribosomal protein</keyword>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007820"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU364105"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OBZ88095.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="192" mass="21401" checksum="3F8D93D1B2C6D402" modified="2016-11-30" version="1" fragment="single">TTMASHKIQKASGAAPADETELAVAQALVDLESSIPELRPLVLSSAKEVELGAGKKALVVFVPVPQLKSYNKIQQKLTRELEKKFSDRHVVFIAQRRILPVPNRRNTGKQPRPRSRTLTAVHDAILDDMVYPTEIVGKRLRQKVDGTKTLKVFLDAKDATSLEYKLDTFSAVYKKLTGKDVAFEFPANTELF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NGV9</accession>
    <name>A0A1C7NGV9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_03729</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000166">
        <property type="protein sequence ID" value="OBZ88230.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NGV9"/>
    <dbReference type="STRING" id="101091.A0A1C7NGV9"/>
    <dbReference type="InParanoid" id="A0A1C7NGV9"/>
    <dbReference type="OrthoDB" id="2257025at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ88230.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="335" mass="38619" checksum="DFF904171B7C33EE" modified="2016-11-30" version="1">MSSHILLNAEVTNLIVRDLVGLNAVDQYLSQAPEWSTKRIFPNVLYSAIDAKKLPPIVIEVVHVVNSNFLHQVVQYCEEVNLRYGVVPLVLIFVVERVQDDITSNTTRHYKYPFLLKLPSFPWAKDCFVVSKSSIQGHLTDMPLHPLVALAIFFTTQKPDLLDHDPTIQKLYNILKKTSENVILNREEIAYDISRICNDFESRLDESVRLLSRLKNTESKKRAIDCLNGGIATLVTYKRKYIPNSSRELSPLTSSSSRSSVSLVATSPSLSENWNFVERFIKDYDKKKMDWKACYSEGKRQGYFTNYTTHISLKNSYQRWKIQHGPPCRSRRRTD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NHL0</accession>
    <name>A0A1C7NHL0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Protein air1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">air1</name>
        <name evidence="10" type="ORF">A0J61_03328</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000141">
        <property type="protein sequence ID" value="OBZ88613.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NHL0"/>
    <dbReference type="STRING" id="101091.A0A1C7NHL0"/>
    <dbReference type="InParanoid" id="A0A1C7NHL0"/>
    <dbReference type="OrthoDB" id="7608935at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031499">
        <property type="term" value="C:TRAMP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071031">
        <property type="term" value="P:nuclear mRNA surveillance of mRNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071039">
        <property type="term" value="P:nuclear polyadenylation-dependent CUT catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071035">
        <property type="term" value="P:nuclear polyadenylation-dependent rRNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071036">
        <property type="term" value="P:nuclear polyadenylation-dependent snoRNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071037">
        <property type="term" value="P:nuclear polyadenylation-dependent snRNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071038">
        <property type="term" value="P:TRAMP-dependent tRNA surveillance pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.60.10">
        <property type="entry name" value="Zinc finger, CCHC-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051644">
        <property type="entry name" value="TRAMP_AT-DNA-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001878">
        <property type="entry name" value="Znf_CCHC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036875">
        <property type="entry name" value="Znf_CCHC_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46543">
        <property type="entry name" value="ZINC FINGER CCHC DOMAIN-CONTAINING PROTEIN 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46543:SF1">
        <property type="entry name" value="ZINC FINGER CCHC DOMAIN-CONTAINING PROTEIN 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00343">
        <property type="entry name" value="ZnF_C2HC"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57756">
        <property type="entry name" value="Retrovirus zinc finger-like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50158">
        <property type="entry name" value="ZF_CCHC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 7" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="CCHC-type" evidence="9">
        <location>
            <begin position="207"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="domain" description="CCHC-type" evidence="9">
        <location>
            <begin position="298"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="50"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="343"/>
            <end position="543"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="8">
        <location>
            <begin position="60"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="118"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="368"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="399"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="429"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="505"/>
            <end position="523"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OBZ88613.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="543" mass="61601" checksum="DC71BD35B67D6B68" modified="2016-11-30" version="1">MFDEDEEELELLRQYEDKALDADDDEKYSSDQMDSDLEDKILSMVQYGSGITKKKTLPTKPEPAIEPTPDSVPEPVVVRAPISDAADQKRPVDFSASEEYGLADTDSDSSESHKAASDTEDESDEGTEDDDDNNSSSNEARENTLADAPQPAVTHYINLDDKRYMENDETSEEEAELGIKLQKLIDDQIFNRQSRKRYQTLKPVRVCFVCNQPGHERKDCNRCMECGLPRHKESRCVGARYCARCKRRGHNAIDCKNAKTSENCKICNVHYHHKSVCPSLLHTYVDEVSPRKIPEAWCYYCTSKGHYGDECPHLPTYLSTIPSAFSKHSIGLGNRFEAKKSMKNSAASFSRQHERWSNTSSRESSPHRNNKKPSKKRPRNDFNSSDTDDSRYDRGNNKSSKKNKKNKGKGNLNEFFDRGSSSRNDDYRSGNSNWKALNNNSLPQPTRSGTVHMNNPKQRSKQGQGNNYSSSFPRGNMSDLPRPSSSGVIDLVNDNHHGHKRNHNHNNNNNNNHGNNHNNNNNNSGGQYSRRAPKYHGGYRQNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NHZ1</accession>
    <name>A0A1C7NHZ1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Multidrug resistance protein fnx1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">fnx1</name>
        <name evidence="8" type="ORF">A0J61_03291</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000139">
        <property type="protein sequence ID" value="OBZ88665.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NHZ1"/>
    <dbReference type="FunCoup" id="A0A1C7NHZ1">
        <property type="interactions" value="31"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NHZ1"/>
    <dbReference type="InParanoid" id="A0A1C7NHZ1"/>
    <dbReference type="OrthoDB" id="10021397at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000329">
        <property type="term" value="C:fungal-type vacuole membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015174">
        <property type="term" value="F:basic amino acid transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd17502">
        <property type="entry name" value="MFS_Azr1_MDR_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1720.10">
        <property type="entry name" value="Multidrug resistance protein D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501:SF191">
        <property type="entry name" value="VACUOLAR BASIC AMINO ACID TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="56"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="94"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="125"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="154"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="188"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="214"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="253"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="285"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="324"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="360"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="387"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="414"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="456"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="527"/>
            <end position="546"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="59"/>
            <end position="551"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OBZ88665.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="556" mass="60164" checksum="03CBE2D61A4693E0" modified="2016-11-30" version="1">MPSTATENARLLNQSSHYGSVEVQDEDTGMISVVTSTGNKSHDDDLLAKRLKGASLMVVLVGLWIGVGLSSLDASIVATIYPQIGTEFKRSNEIVWIATAYMLSYTALQPLYGRVSDALGRRRTILFATIVFFIGSGLCGASNSLWALVISRTIAGVGGGGMNTMSAVITSDLVSLRERGKYQGYANIAYGLGSVIGAPLGGLITDNVGWRYCFYINLPLLLISIYVGIYLLTDYNLEEDASGSTLYQRFKKIDFLGAFFVVISVVCFLVATSLGGNSRAWTDPVVYGLLIASVLMATCFCLVEAKVAQNPLMPWHIISKRTPFASSLVNFFGVMCSFAMTYTTPLFFQGVLGYSSSQAGLFFLPKVIAMSCGSLASGFWMARTGEYCRFITFSALVALISMIGISLWTPDTSLVFIVICLILDGFSSGSLVTTALVSMLSCVNSTDMATITSISYLFRSTGGVIGISVTSAIFQGVVKRVLSERITGPDREAIIEIARKSMNQVREVLPPDALEIVLDTYQVAVSYAFYFCALISLLSVISTLFIQQYQLHSKLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NI11</accession>
    <name>A0A1C7NI11_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Zinc finger protein OZF</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">ZNF146</name>
        <name evidence="7" type="ORF">A0J61_03265</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000137">
        <property type="protein sequence ID" value="OBZ88685.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NI11"/>
    <dbReference type="STRING" id="101091.A0A1C7NI11"/>
    <dbReference type="InParanoid" id="A0A1C7NI11"/>
    <dbReference type="OrthoDB" id="654211at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000785">
        <property type="term" value="C:chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031519">
        <property type="term" value="C:PcG protein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005667">
        <property type="term" value="C:transcription regulator complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000125">
        <property type="entry name" value="Putative zinc finger protein 143"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:001297">
        <property type="entry name" value="Zinc finger and SCAN domain-containing protein 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14003">
        <property type="entry name" value="TRANSCRIPTIONAL REPRESSOR PROTEIN YY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14003:SF19">
        <property type="entry name" value="YY2 TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="6">
        <location>
            <begin position="17"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="6">
        <location>
            <begin position="47"/>
            <end position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OBZ88685.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="92" mass="10863" checksum="5186151C677788B1" modified="2016-11-30" version="1">MNIQNLLNNPIIEEKLFACTWIECSKSFSRRSDLLRHTRIHTGERPYHCKWPSCGKQFIQRSALTVHYRTHTGERPHVCEYTPCGKTFSDVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NI36</accession>
    <name>A0A1C7NI36_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_03232</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000136">
        <property type="protein sequence ID" value="OBZ88715.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NI36"/>
    <dbReference type="InParanoid" id="A0A1C7NI36"/>
    <dbReference type="OrthoDB" id="2301950at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="61"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="27"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="165"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ88715.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="165" mass="18237" checksum="7044E4B4437F4A1F" modified="2016-11-30" version="1" fragment="single">MKKSEHANRVVAQEDSTTKRGRPFGTTKATLLKTHSSNQSRMTSFLSNQDDAMISNQNATDLVSTTSPDDSFIITDNSADTNKATQSVSQCSEMESRLEGVVSNLEVQNSNSIVNDCITNEPAEEERSSRVSEGRVIDGFEEELLDDLNEEIIEQMDREAGLVEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NI62</accession>
    <name>A0A1C7NI62_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Rab3 GTPase-activating protein catalytic subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">rab3gap1</name>
        <name evidence="8" type="ORF">A0J61_03118</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the Rab3-GAP catalytic subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000129">
        <property type="protein sequence ID" value="OBZ88822.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NI62"/>
    <dbReference type="STRING" id="101091.A0A1C7NI62"/>
    <dbReference type="InParanoid" id="A0A1C7NI62"/>
    <dbReference type="OrthoDB" id="17346at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045700">
        <property type="entry name" value="Rab3GAP1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026147">
        <property type="entry name" value="Rab3GAP1_conserved"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21422">
        <property type="entry name" value="RAB3 GTPASE-ACTIVATING PROTEIN CATALYTIC SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21422:SF9">
        <property type="entry name" value="RAB3 GTPASE-ACTIVATING PROTEIN CATALYTIC SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13890">
        <property type="entry name" value="Rab3-GTPase_cat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0343">GTPase activation</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rab3GAP catalytic subunit conserved" evidence="7">
        <location>
            <begin position="548"/>
            <end position="694"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="357"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="366"/>
            <end position="377"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008856"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00015817"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022468"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF13890"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OBZ88822.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="867" mass="99981" checksum="3D96EAD5C80DD74B" modified="2016-11-30" version="1">MSSTIKRRQSSTYSEDLSRYEFVDYTAASDFEKLITHIEEIISTWGLKEGSNGIFSDHTQTPGDIRKEKINLTDDTYELVYHYHPSSVQSNTLAFPDFYQYGFQFHPLHRWTGLSRLLILRPLQDSFRKKMLGSTGQSTQLSQAKQLISACAIAFQNTGCCLPIFVPLGQHRHELYTGYRMNRQPGTLFDQTESRFNMSLVPLTSPFYSLEEVRTLFIQKLIQQQDDYGISKPSPISMTTVLTYNLKTWFDERWKEWDESPTPKRRTSFSDESDAWEEEADQMTLPFGSLNDPLRSLTLNAIFPFTDQIPEEPMDALTAAEWQLAREFAPDHQQRAYLAHLLDTAIQSWVQDPSNQSYLAPFDENNKEEEDEDEEENSMVHSSLIQQGDDQVTLITSDLVEDILTRLFTSEVKAGKPLIQSPHVVPYRSLLWNMVYYSLKAMVDQKESFIGLLRVVWLQVLHKIRWHWEHHLPLPHVSPYLYDQTEDVLGIDLRYPLIHQKLCMINCCIHRLNKSDALSEESDLFVDAVEDDLDGSYISLAQDQQEEDSMEGQVGSHPTLTLLKTGQPMQIPITQDPGFMTEDMVNEQADVFEKLGTSNDATQKRARLQSAQLLSDMQAFKAANPYACLEDFVRWHSPRDWIVVDGQGQLSARMSEPNNIWQELWQSAKRIPCARQQPLFDVTKEAEKALVYLETLSVQDVFAILLPTCGFIAYDTLANHPVVQFSQKVKQGLDNLGQQLTQFPWEDLRHGKQTFHTLSNCIRQQESRMCHAISLARKLPQQARLVDLLIEHDQAKVQEGQERSIVFELFKNDQNVISEPSYKEYMFYSDCQELTGHDRALPARQYALVKENEIRLVEMQSTDALYS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NIY7</accession>
    <name>A0A1C7NIY7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_02995</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000122">
        <property type="protein sequence ID" value="OBZ88958.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NIY7"/>
    <dbReference type="InParanoid" id="A0A1C7NIY7"/>
    <dbReference type="OrthoDB" id="2344405at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ88958.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="354" mass="40954" checksum="234763412D60919A" modified="2016-11-30" version="1">MATAYYPMFFSPLSQPESDFQKQEEPKEEINNYLIDLPATCQFDSNENWDYVLSQMRQQIFNSSTVSYQSPERHIIKKTQESNPVLADELVMATKSNALHDLSDPNILRSSDPLSYRRYRSENLLLRMIHCRKLDLDQVSLMRLSRGVFIHQKWQSSVSHPSPTLSAIEDALGFIDDTRGEAPIDTFQFDTTLFKSNLTRSCFDMFVPYSYTLGARYTNPYNGAHDLVIRGKLPLWCQTLFLSTCLKQAKPIQSHVPQYGLFPYLPQVAVVFKPWNEEDYGDLIMPDLALTYELFTLEHYDPLLSIDQNDFDYQWPRKKKEILQNMLVCDLPDDFAAFLSEMAASWAANQGLMI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NJ01</accession>
    <name>A0A1C7NJ01_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Exopolygalacturonase rpg16</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">rpg16_5</name>
        <name evidence="12" type="ORF">A0J61_02821</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the glycosyl hydrolase 28 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000112">
        <property type="protein sequence ID" value="OBZ89127.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NJ01"/>
    <dbReference type="InParanoid" id="A0A1C7NJ01"/>
    <dbReference type="OrthoDB" id="187139at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004650">
        <property type="term" value="F:polygalacturonase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046576">
        <property type="term" value="F:rhamnogalacturonan alpha-L-rhamnopyranosyl-(1-&gt;4)-alpha-D-galactopyranosyluronide lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.20.10">
        <property type="entry name" value="Single-stranded right-handed beta-helix, Pectin lyase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000743">
        <property type="entry name" value="Glyco_hydro_28"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012334">
        <property type="entry name" value="Pectin_lyas_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011050">
        <property type="entry name" value="Pectin_lyase_fold/virulence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31736">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31736:SF19">
        <property type="entry name" value="PECTIN LYASE SUPERFAMILY PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00295">
        <property type="entry name" value="Glyco_hydro_28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51126">
        <property type="entry name" value="Pectin lyase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="6" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="7" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="8 10" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="5 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0964">Secreted</keyword>
    <keyword evidence="4 11" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="11">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008889725" evidence="11">
        <location>
            <begin position="24"/>
            <end position="381"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008834"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU361169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="OBZ89127.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="381" mass="40296" checksum="1A761ACF1FBE15E3" modified="2016-11-30" version="1">MVYIPSLSSSLALITVLASAAQAATTCTVATGGDAAKSIASAFEACKNGGTVVFTKGATYNLQSLVEVENLKNVNVQFYGTVNLPGFNSKHAGENSYFRIKGDGIQWDGGKVGTFNGNGQKWWDAENREAPTVFRIQATNSYFGNFNIVQSPRAHIGITSSNSVKLDGITLKTVSKSSKPAKNTDAVDISNSSNIEFTNSVLTVGDDCTAMNNDVXNVVIKNVKCTGGHGFSIGSLGKGGSSATVKNISIQNSVCDNCQNGIRIKTWPGGKGSVSAVTFKDVKLNNVENPVLITTHYCDKNQQSFCNGNDNHSLTIKDITMQNISGSTSTSKSNPAISINCSKDTPCSGFKMTNVNISTHSKTKKNECINLSGSSSISYCK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NJ16</accession>
    <name>A0A1C7NJ16_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Bromodomain testis-specific protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">BRDT</name>
        <name evidence="6" type="ORF">A0J61_02859</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000114">
        <property type="protein sequence ID" value="OBZ89091.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NJ16"/>
    <dbReference type="STRING" id="101091.A0A1C7NJ16"/>
    <dbReference type="InParanoid" id="A0A1C7NJ16"/>
    <dbReference type="OrthoDB" id="21449at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000785">
        <property type="term" value="C:chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006338">
        <property type="term" value="P:chromatin remodeling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.920.10">
        <property type="entry name" value="Bromodomain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050935">
        <property type="entry name" value="Bromo_chromatin_reader"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001487">
        <property type="entry name" value="Bromodomain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036427">
        <property type="entry name" value="Bromodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018359">
        <property type="entry name" value="Bromodomain_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22880:SF225">
        <property type="entry name" value="BROMODOMAIN-CONTAINING PROTEIN BET-1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22880">
        <property type="entry name" value="FALZ-RELATED BROMODOMAIN-CONTAINING PROTEINS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00439">
        <property type="entry name" value="Bromodomain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00503">
        <property type="entry name" value="BROMODOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00297">
        <property type="entry name" value="BROMO"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47370">
        <property type="entry name" value="Bromodomain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00633">
        <property type="entry name" value="BROMODOMAIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50014">
        <property type="entry name" value="BROMODOMAIN_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0103">Bromodomain</keyword>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Bromo" evidence="5">
        <location>
            <begin position="42"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="domain" description="Bromo" evidence="5">
        <location>
            <begin position="243"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="335"/>
            <end position="530"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="536"/>
            <end position="582"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="338"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="385"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="436"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="457"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="488"/>
            <end position="508"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="513"/>
            <end position="530"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OBZ89091.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="764" mass="87476" checksum="0A12946CD1F3EDE3" modified="2016-11-30" version="1">MSHVAQKRSFSSLQDDEPIKTTQAVMSPAEKKWCIQTIRSLKKHKRAIAFLDPVDPIYFNIPDYFDIVKHPMDLGTVERKLLADKYLNVDAFKSDVQLIFDNCYLYNNPGDPVCLDAKKLEEHYQKLCKKEPSLMTVPLPTPPSLVTGAVSTEYPSMDLDHNYIDSSSIPSSAPPPSINHTPNPTTIKLAVQKPQSIPPLSPPIHTSLPDTAMDNVNTASPTTMPEDQFKRCEALVRELKKPKYKGYAWPFENPVDAAAWGATDYYEIIKQPMDMSTYEKKLYNHQYSHEEQLAEDIRLMFRNCYMYNPPDHLVTNLGKEFEAVFERQWAKLHQQNPIKKKKSVNKKQRTSSSSSMLDDDYVQDEPLPPTLPEPTTEPNHEMPTPTETKSNNGPTILRLKIKVSQPKEEPTISTPSSPPKPKIPGLALSKEPPTPTTNTPITNGPKLAIGTKPPSPVKEKKVDKPMLANHDKWLALAKKTSPPPSSQPPSQLSSQLPSTLPKLPTTPTNQFKPKKEPTPSKPKEADIKPFDIADIYSQIHNEKRLKEQQKREEQEKWERMEKTRLEQERIATEKRMHELREQSRKFKARKEQDKRMRLEALNAVSIDISQQKMRFNEYEKEHMSRDQDWHDVYVWQRDTNDYRHMPAPGFVKRAQIKLPELRKRLLSKCVRLENSKNYQPIDMVDDGAAAAATVASNNPRSTLLLESPSYLGHIVLQFTRQVMRPKIVLPMFFMIVLLFDLEGSLDLDDDLFNDDNDDNASHPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NJB9</accession>
    <name>A0A1C7NJB9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">O-glycoside alpha-1,2-mannosyltransferase 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">omh2</name>
        <name evidence="4" type="ORF">A0J61_02738</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the glycosyltransferase 15 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000107">
        <property type="protein sequence ID" value="OBZ89201.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NJB9"/>
    <dbReference type="InParanoid" id="A0A1C7NJB9"/>
    <dbReference type="OrthoDB" id="76388at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000026">
        <property type="term" value="F:alpha-1,2-mannosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008061">
        <property type="term" value="F:chitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000032">
        <property type="term" value="P:cell wall mannoprotein biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006487">
        <property type="term" value="P:protein N-linked glycosylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.50.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="entry name" value="Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011583">
        <property type="entry name" value="Chitinase_II/V-like_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029070">
        <property type="entry name" value="Chitinase_insertion_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001223">
        <property type="entry name" value="Glyco_hydro18_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002685">
        <property type="entry name" value="Glyco_trans_15"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31121">
        <property type="entry name" value="ALPHA-1,2 MANNOSYLTRANSFERASE KTR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31121:SF6">
        <property type="entry name" value="ALPHA-1,2 MANNOSYLTRANSFERASE KTR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00704">
        <property type="entry name" value="Glyco_hydro_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01793">
        <property type="entry name" value="Glyco_transf_15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00636">
        <property type="entry name" value="Glyco_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51910">
        <property type="entry name" value="GH18_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="GH18" evidence="3">
        <location>
            <begin position="351"/>
            <end position="752"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OBZ89201.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="810" mass="92372" checksum="065426A7327B94B4" modified="2016-11-30" version="1">MSYQDFYGDRFATHQIKLYNSPSYDYLLPDTKLDWNAVNSSLQTKAAFVSVVHENDLYGLRVSILDIEDRFNRQHGYPWVIVSEKALSRKFREWITSSTTAPVFFGQAPAIEWNEPYWIDMQLAEKNLRQLVKTTDNPDVESMNFRKMTRYNAGFLAYHPLLRNLEYTWRVQPGSRYTCDILEDPFEKMKRENKKLSFASTTTENHVNIEGLQDKVFEFIQQNRDIVVPTSKSIYKALLNDATRSSPIDLNNPLGEYHGHFSNCMIDNSLMIASLQFLRSKEYTQFFEALDLSGGFFYHKWGESMPQTVAAALFLERSEIDYDHVIGYEYGYISICPSEFKAHAHVSEKDKVVVGYWGYWESKLLPIEYIPWSQITHLNYGFATMEDEVVPKLSNPAQLMKVVGIAHQNNVKVLLSIGGWYGSRSMSKMASTLDGRTQFVEKAVEWILQFGIDIDWEYPGKSALECNTLDYANDTDNYLLLLKQLREALDNAFSTIKPSTTDTTYYKHLYTNGTNKDEDHKLLTLAVGTVPFSKSNAPITDVSSFSAVIDWVFVMMYDTYVGKSVIGPNAPLQTSKQEGSTKQSFAQAWEAWATAHMPPEKIIMGLPLYGYVSKPKEDVVHLKRLLVTAHASKPQGDAEDELSQSPCPNSRRAYSGMWKWRSLLSSGILLDYKTPGGQWIKNWDVESQTPWLYNPVTHHLIVYDDPDSIALKVDFAICKGARGVGVWDVTYDDYSQKKGQLLDVINQELSNNDQKEACQRISPIAPYKVVGPQFNALSKEQLYSNAVKLAPTTLVFFAFLCAVFSLANQI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NJM5</accession>
    <name>A0A1C7NJM5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Peptidyl-prolyl cis-trans isomerase</fullName>
            <shortName evidence="4">PPIase</shortName>
            <ecNumber evidence="4">5.2.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">cyp1</name>
        <name evidence="6" type="ORF">A0J61_02601</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)</text>
            <dbReference type="Rhea" id="RHEA:16237"/>
            <dbReference type="Rhea" id="RHEA-COMP:10747"/>
            <dbReference type="Rhea" id="RHEA-COMP:10748"/>
            <dbReference type="ChEBI" id="CHEBI:83833"/>
            <dbReference type="ChEBI" id="CHEBI:83834"/>
            <dbReference type="EC" id="5.2.1.8"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the cyclophilin-type PPIase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.2.1.8" evidence="4"/>
    <dbReference type="EMBL" id="LUGH01000100">
        <property type="protein sequence ID" value="OBZ89352.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NJM5"/>
    <dbReference type="FunCoup" id="A0A1C7NJM5">
        <property type="interactions" value="254"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NJM5"/>
    <dbReference type="InParanoid" id="A0A1C7NJM5"/>
    <dbReference type="OrthoDB" id="193499at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016018">
        <property type="term" value="F:cyclosporin A binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01926">
        <property type="entry name" value="cyclophilin_ABH_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.100.10:FF:000013">
        <property type="entry name" value="Peptidyl-prolyl cis-trans isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.100.10">
        <property type="entry name" value="Cyclophilin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029000">
        <property type="entry name" value="Cyclophilin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024936">
        <property type="entry name" value="Cyclophilin-type_PPIase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020892">
        <property type="entry name" value="Cyclophilin-type_PPIase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002130">
        <property type="entry name" value="Cyclophilin-type_PPIase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11071">
        <property type="entry name" value="PEPTIDYL-PROLYL CIS-TRANS ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11071:SF561">
        <property type="entry name" value="PEPTIDYL-PROLYL CIS-TRANS ISOMERASE D-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00160">
        <property type="entry name" value="Pro_isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001467">
        <property type="entry name" value="Peptidylpro_ismrse"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00153">
        <property type="entry name" value="CSAPPISMRASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50891">
        <property type="entry name" value="Cyclophilin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00170">
        <property type="entry name" value="CSA_PPIASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50072">
        <property type="entry name" value="CSA_PPIASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4 6" id="KW-0413">Isomerase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0697">Rotamase</keyword>
    <feature type="domain" description="PPIase cyclophilin-type" evidence="5">
        <location>
            <begin position="8"/>
            <end position="164"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OBZ89352.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="165" mass="17807" checksum="677C7A899D6D709C" modified="2016-11-30" version="1">MSNNPKVFFDVSIGGQPAGRISFELFQDEVPKTAENFRALCTGEKGFGYKGCSFHRIIPQFMLQGGDFTNHNGTGGKSIYGEKFADENFKIKHTVPGLLSMANAGKNTNGSQFFITTVPCPWLDGKHVVFGKVIDGFDIVSKIESYGSGSGTPKAKVIIEDCGAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NJR1</accession>
    <name>A0A1C7NJR1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Transcription factor domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">A0J61_02716</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000106">
        <property type="protein sequence ID" value="OBZ89228.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NJR1"/>
    <dbReference type="STRING" id="101091.A0A1C7NJR1"/>
    <dbReference type="InParanoid" id="A0A1C7NJR1"/>
    <dbReference type="OrthoDB" id="2265990at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050815">
        <property type="entry name" value="TF_fung"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47338:SF5">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47338">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="3"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OBZ89228.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="591" mass="69393" checksum="F76D56F35265DDD6" modified="2016-11-30" version="1">MNEDENQKKLEAYNAQIRQLEETIQCMEKEVEHYRSHSLTTTTTATSTIIPSDFYGWKFHMHNGMISIDTGIKSISDLLPLSYLSPLSADWGSFDQKEECDIYLNNRSDLLLQFMQETNSSWISFFLSLLERPNQPNRRLILPAPRSLVSQALFDQLVTIFFQCHNMYKLCLHKPSFEAHYATLEDVLSDVITLSVCCYVCTTPCNHLDMINPQEQRALADFLFDRCKSMILDQFDDYEKRFENVAAIVLLVQYMHFTLRFSDCRHLLDLAYSLCLDIQREMTDEHLTIQQALFKRHFYFIVYFRRIINCVANDSFFSESCHIPLLDEVEDESEESKRWIRALNWSIRAFDHPFITRVLRQVNLAYIGQIGVFSFESMVKLEIIIDEWISIVPDDIRLCHDYHSQEACEAAIRQTTDDVKLFSFADFCVLHLWVYCFLLKPLPDQRMNEQMSRYVLQKSLEKSAKYCYLAVRAIHRMFEVALNERRCDMSLVGCDSLLVTIDLLLILTSSDSRYLAKDTRELIHSIYRMLNKFHFMYNICATYGPSPMESILSGAKQSMRFHIEYYDQLSHPWLSVVYDATCYISHFDTSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NJW8</accession>
    <name>A0A1C7NJW8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_02653</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000102">
        <property type="protein sequence ID" value="OBZ89298.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NJW8"/>
    <dbReference type="STRING" id="101091.A0A1C7NJW8"/>
    <dbReference type="InParanoid" id="A0A1C7NJW8"/>
    <dbReference type="OrthoDB" id="1938591at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="63"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="2"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="63"/>
            <end position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ89298.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="227" mass="26499" checksum="E24B3BF02F416271" modified="2016-11-30" version="1">MMHLLQQQQQQQQQQAQQQQQAQQQLQQQLQQQQQQLQQQQQQQQQQQQQQQLLQQQQQQLHSLPSAQVPQPQQTQVQIPSPQTQLQQQQALPRPVTSISTMRPGMGPDDKISNTMMYVNDVLKDVAAILAVADRTQEPEPSMQVVKEERSHTALLFEPYTLELESEENDIMIENDVKKETLDEKEVLNSWYEVGMDTSVLRLNEIMTGFCWNDNDCEQKRRFSSCC</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NK56</accession>
    <name>A0A1C7NK56_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Cupin 2 conserved barrel domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_03075</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000126">
        <property type="protein sequence ID" value="OBZ88876.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NK56"/>
    <dbReference type="InParanoid" id="A0A1C7NK56"/>
    <dbReference type="OrthoDB" id="2225991at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="entry name" value="Jelly Rolls"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="RmlC-like cupins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ88876.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="127" mass="14500" checksum="6BB607F1E08BA05B" modified="2016-11-30" version="1">MISSVHTSLLKNKQSEDHYTPIPQFPACLGGQWKNLTITPYLKTTMKFSAGTSLPPHHFPAMSRITVLSGSIQIDDLQTSQAYILHASENCVIPALLVHELQFLEDVEFEFELNSNEMTIYWDFEER</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NL50</accession>
    <name>A0A1C7NL50_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ADP-ribosylation factor-like protein 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">ARL3</name>
        <name evidence="5" type="ORF">A0J61_02398</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000089">
        <property type="protein sequence ID" value="OBZ89559.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NL50"/>
    <dbReference type="STRING" id="101091.A0A1C7NL50"/>
    <dbReference type="InParanoid" id="A0A1C7NL50"/>
    <dbReference type="OrthoDB" id="414781at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043001">
        <property type="term" value="P:Golgi to plasma membrane protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034067">
        <property type="term" value="P:protein localization to Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd04160">
        <property type="entry name" value="Arfrp1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:001317">
        <property type="entry name" value="Putative ADP-ribosylation factor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024156">
        <property type="entry name" value="Small_GTPase_ARF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006689">
        <property type="entry name" value="Small_GTPase_ARF/SAR"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45909">
        <property type="entry name" value="ADP-RIBOSYLATION FACTOR-RELATED PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45909:SF1">
        <property type="entry name" value="ADP-RIBOSYLATION FACTOR-RELATED PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00025">
        <property type="entry name" value="Arf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00449">
        <property type="entry name" value="RASTRNSFRMNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00177">
        <property type="entry name" value="ARF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00175">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00178">
        <property type="entry name" value="SAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51417">
        <property type="entry name" value="ARF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51419">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="4" id="KW-0460">Magnesium</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="24"/>
            <end position="31"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="31"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="55"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="77"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="133"/>
            <end position="136"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR606689-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR606689-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OBZ89559.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="198" mass="22327" checksum="759892044D4D199D" modified="2016-11-30" version="1">MYTLLSGLYHHLTRKEEYYVLIIGLDNAGKTTLLERIKAIYTGTSGLDPDKIAPTVGLNIGKVNIKSSRINFWDLGGQKDLHSIWERYYSECHAIVFVVDSTDPIRLEDCRDTFEKMITNDAVEGVPILMLANKQDVSGALKVEEVKEVFNKIAMKLGARDSRVLSVSALEGHGVEDAIDWLVLRLQRNKTNRPPILR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NLB9</accession>
    <name>A0A1C7NLB9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">ATPase inhibitor, mitochondrial</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">A0J61_02151</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Inhibits the enzyme activity of ATPase.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 4">Belongs to the ATPase inhibitor family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000078">
        <property type="protein sequence ID" value="OBZ89798.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NLB9"/>
    <dbReference type="STRING" id="101091.A0A1C7NLB9"/>
    <dbReference type="InParanoid" id="A0A1C7NLB9"/>
    <dbReference type="OrthoDB" id="5532350at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042030">
        <property type="term" value="F:ATPase inhibitor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.500">
        <property type="entry name" value="Single helix bin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007648">
        <property type="entry name" value="ATPase_inhibitor_mt"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04568">
        <property type="entry name" value="IATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010901"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU368087"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OBZ89798.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="86" mass="9608" checksum="07A7880070A7DA16" modified="2016-11-30" version="1">MFSQLSTRVSGRTNILSRRALHMTSIARSEGATASSKGFSEREAAAENRWARAHDAEKIKILREHLAAQEQSTADIKKKLAELEKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NLG3</accession>
    <name>A0A1C7NLG3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">DNA repair protein RAD14</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">rhp14</name>
        <name evidence="13" type="ORF">A0J61_02241</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the XPA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000082">
        <property type="protein sequence ID" value="OBZ89699.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NLG3"/>
    <dbReference type="FunCoup" id="A0A1C7NLG3">
        <property type="interactions" value="253"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NLG3"/>
    <dbReference type="InParanoid" id="A0A1C7NLG3"/>
    <dbReference type="OrthoDB" id="68328at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000110">
        <property type="term" value="C:nucleotide-excision repair factor 1 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003684">
        <property type="term" value="F:damaged DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006284">
        <property type="term" value="P:base-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901255">
        <property type="term" value="P:nucleotide-excision repair involved in interstrand cross-link repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000715">
        <property type="term" value="P:nucleotide-excision repair, DNA damage recognition"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070914">
        <property type="term" value="P:UV-damage excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd21077">
        <property type="entry name" value="DBD_Rad14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.530.10:FF:000003">
        <property type="entry name" value="Dna repair rad14 protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.530.10">
        <property type="entry name" value="XPA C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009061">
        <property type="entry name" value="DNA-bd_dom_put_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000465">
        <property type="entry name" value="XPA/RAD14"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022656">
        <property type="entry name" value="XPA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022658">
        <property type="entry name" value="XPA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037129">
        <property type="entry name" value="XPA_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00598">
        <property type="entry name" value="rad14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10142">
        <property type="entry name" value="DNA REPAIR PROTEIN COMPLEMENTING XP-A CELLS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10142:SF0">
        <property type="entry name" value="DNA REPAIR PROTEIN COMPLEMENTING XP-A CELLS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05181">
        <property type="entry name" value="XPA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46955">
        <property type="entry name" value="Putative DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00753">
        <property type="entry name" value="XPA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0227">DNA damage</keyword>
    <keyword evidence="8" id="KW-0234">DNA repair</keyword>
    <keyword evidence="7" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <keyword evidence="5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="XPA C-terminal" evidence="12">
        <location>
            <begin position="141"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="30"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="236"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="236"/>
            <end position="255"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005548"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00072989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF05181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="OBZ89699.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="279" mass="32666" checksum="02A4D42928C57405" modified="2016-11-30" version="1">MMSTPVDVQKQLTQEQIERIAKNKAAALERLKETNKRKREEAEQQKKDAPKKARWIKSFYEYDLSTMVDLKGGFILDETTEDKQKEEKKKLYNIEPYFPSSSDPAENPKCKECQSLDLDPVFFSVFHINLCPTCKDKYPEKYSLITKTEAKEDYLLTDPELKDPELLPHWSKPNPHKSTWNDMMLYVREMVEEYAFKKWGGAEGLDAEYERRVAQKQEKKEKKFKEKLADLRRRTLTTAKERKRQEGPHKHEFGDVKGQGGATVQKCLTCGLVIESEEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NLH8</accession>
    <name>A0A1C7NLH8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Proteasome subunit alpha type</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">Psma1</name>
        <name evidence="8" type="ORF">A0J61_02122</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="5">The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="5">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 5">Belongs to the peptidase T1A family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000076">
        <property type="protein sequence ID" value="OBZ89820.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NLH8"/>
    <dbReference type="FunCoup" id="A0A1C7NLH8">
        <property type="interactions" value="627"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NLH8"/>
    <dbReference type="InParanoid" id="A0A1C7NLH8"/>
    <dbReference type="OrthoDB" id="431557at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019773">
        <property type="term" value="C:proteasome core complex, alpha-subunit complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034515">
        <property type="term" value="C:proteasome storage granule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010499">
        <property type="term" value="P:proteasomal ubiquitin-independent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043161">
        <property type="term" value="P:proteasome-mediated ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd03749">
        <property type="entry name" value="proteasome_alpha_type_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.20.10:FF:000016">
        <property type="entry name" value="Proteasome subunit alpha type-6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.10">
        <property type="entry name" value="Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050115">
        <property type="entry name" value="Proteasome_alpha"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023332">
        <property type="entry name" value="Proteasome_alpha-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035144">
        <property type="entry name" value="Proteasome_alpha1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000426">
        <property type="entry name" value="Proteasome_asu_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001353">
        <property type="entry name" value="Proteasome_sua/b"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11599">
        <property type="entry name" value="PROTEASOME SUBUNIT ALPHA/BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00227">
        <property type="entry name" value="Proteasome"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10584">
        <property type="entry name" value="Proteasome_A_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00948">
        <property type="entry name" value="Proteasome_A_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="N-terminal nucleophile aminohydrolases (Ntn hydrolases)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00388">
        <property type="entry name" value="PROTEASOME_ALPHA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51475">
        <property type="entry name" value="PROTEASOME_ALPHA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="2 4 5" id="KW-0647">Proteasome</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Proteasome alpha-type subunits" evidence="7">
        <location>
            <begin position="6"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="239"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="243"/>
            <end position="255"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00808"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU000551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS00388"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OBZ89820.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="262" mass="29057" checksum="C88917B19BBB74EA" modified="2016-11-30" version="1">MFRNQYDNDVSTWSPQGRIHQVEYAVEAVKQGSAAIGLRSKKYAILLALKRSSGELASYQKKLIKIDDHMGIGIAGLTSDARVLSNFMRSEAMKSKMLYDRPLPTQRIVNAIADKAQVNTQQYGRRPYGVGLLVIGHDETGPHLFECSPSGTSFEYHAMSIGARSQSAKTYLERYYEEFADASLEELVRHGLQALRDTLQQDKDLNIHNTSIGIVGEDHPFEIVEGEALQTYLNLLGEETGRTRPSGSGVATTTAEPMETDN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NLJ1</accession>
    <name>A0A1C7NLJ1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_02023</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000072">
        <property type="protein sequence ID" value="OBZ89925.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NLJ1"/>
    <dbReference type="InParanoid" id="A0A1C7NLJ1"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ89925.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="81" mass="9273" checksum="C24F3F41B078280D" modified="2016-11-30" version="1" fragment="single">MMQAPHQQQQQQQPYSHHQYYQQYYQHYGDGSAGANTSSSTNNTGYDYNYSQYYYPYNQSNYAHSSPPPPPPSTSSSTTTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NLJ7</accession>
    <name>A0A1C7NLJ7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">DNA-binding protein RFX2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">rfx2</name>
        <name evidence="4" type="ORF">A0J61_01949</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000068">
        <property type="protein sequence ID" value="OBZ90003.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NLJ7"/>
    <dbReference type="FunCoup" id="A0A1C7NLJ7">
        <property type="interactions" value="417"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NLJ7"/>
    <dbReference type="InParanoid" id="A0A1C7NLJ7"/>
    <dbReference type="OrthoDB" id="10056949at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.10:FF:000422">
        <property type="entry name" value="DNA-binding protein RFX7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003150">
        <property type="entry name" value="DNA-bd_RFX"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039779">
        <property type="entry name" value="RFX-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057321">
        <property type="entry name" value="RFX1-4/6/8-like_BCD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12619">
        <property type="entry name" value="RFX TRANSCRIPTION FACTOR FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12619:SF5">
        <property type="entry name" value="TRANSCRIPTION FACTOR RFX4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25340">
        <property type="entry name" value="BCD_RFX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02257">
        <property type="entry name" value="RFX_DNA_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51526">
        <property type="entry name" value="RFX_DBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RFX-type winged-helix" evidence="3">
        <location>
            <begin position="53"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="512"/>
            <end position="561"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="512"/>
            <end position="527"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="535"/>
            <end position="551"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51526"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OBZ90003.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="561" mass="64925" checksum="93B9EA6CC00B35A0" modified="2016-11-30" version="1">MDTETNKEHKSNNENSQERSLVPASSSSALAISDSLEVLDSTLIADKESSMVVTRWVRANYVEEREHNVPRKDMFEHYKAYCVANGLRPVNSATFGKLLRIVFPSLKTRRLGVRGQSKYHYCGIRVKNAYDSGNMALMSEHQSVRSPAVRASASISYLPSTSTRLPYGNEASSSMQESDALPAFVVPLVPSYRYSHEIDFELANSFTLAYEKHCKKILHMISTHQIQKVRSTMQEFYQTMPAKFMNLIQSVPEIIESIWRWDCSLYDASMSLAIINTVLPSVSHSLTQTMATVLRTYTRELKEYIENALINFPTLLLQRKLDVARIFSAKCRRQLSLNFAAQTASDALNRMEQLVVMRQDWDRFDVDGILDQTLWICDCDANEVRAILRNEIYDLLNNKPVIEQWMEWIASIVARYLKRYMPSSPNEINQYLSRSKQLLLKWNYYTSLIMKELSLQQAQSFTSFQNLRLFLDDYIVFLVEENIAQMNFIISHHHQTQQQMHQQQIQQQQQQQQQQQQQQQQQQQQQQYKTEDESFFNYNSSSPSSTNGNGSDQSKGKPFSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NLN8</accession>
    <name>A0A1C7NLN8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">PHO85 cyclin-1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">PCL1_1</name>
        <name evidence="2" type="ORF">A0J61_01954</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000068">
        <property type="protein sequence ID" value="OBZ90012.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NLN8"/>
    <dbReference type="STRING" id="101091.A0A1C7NLN8"/>
    <dbReference type="InParanoid" id="A0A1C7NLN8"/>
    <dbReference type="OrthoDB" id="10250320at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000307">
        <property type="term" value="C:cyclin-dependent protein kinase holoenzyme complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016538">
        <property type="term" value="F:cyclin-dependent protein serine/threonine kinase regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019901">
        <property type="term" value="F:protein kinase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd20557">
        <property type="entry name" value="CYCLIN_ScPCL1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.10">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036915">
        <property type="entry name" value="Cyclin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006671">
        <property type="entry name" value="Cyclin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013922">
        <property type="entry name" value="Cyclin_PHO80-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15615">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15615:SF10">
        <property type="entry name" value="PHO85 CYCLIN-2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00134">
        <property type="entry name" value="Cyclin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47954">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cyclin N-terminal" evidence="1">
        <location>
            <begin position="56"/>
            <end position="158"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ90012.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="179" mass="20652" checksum="9610D5ED2C6EE558" modified="2016-11-30" version="1">MLQKPPTYNFAITRPHNLSTCRLSRNTSIPSVMIDFTAMTLCDLISTKRTKCRSLPEFVYFVQKVTHNANINVRTLLVALIYLKRAKSNLPKRAVGSDDTNHRMFLASLLIASKFLQDTAWTADALTNRRIYEICSGLFSLEEVNQFERGFLKLIQYECWVDDEALNRFVELHRSDLSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NLR8</accession>
    <name>A0A1C7NLR8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Suppressor of ferric uptake 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">SFU1_0</name>
        <name evidence="11" type="ORF">A0J61_02553</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000097">
        <property type="protein sequence ID" value="OBZ89396.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NLR8"/>
    <dbReference type="STRING" id="101091.A0A1C7NLR8"/>
    <dbReference type="InParanoid" id="A0A1C7NLR8"/>
    <dbReference type="OrthoDB" id="515401at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000122">
        <property type="term" value="P:negative regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00202">
        <property type="entry name" value="ZnF_GATA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.50.10:FF:000007">
        <property type="entry name" value="Nitrogen regulatory AreA, N-terminal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.50.10">
        <property type="entry name" value="Erythroid Transcription Factor GATA-1, subunit A"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039355">
        <property type="entry name" value="Transcription_factor_GATA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000679">
        <property type="entry name" value="Znf_GATA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013088">
        <property type="entry name" value="Znf_NHR/GATA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10071:SF335">
        <property type="entry name" value="IRON-SENSING TRANSCRIPTIONAL REPRESSOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10071">
        <property type="entry name" value="TRANSCRIPTION FACTOR GATA FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00320">
        <property type="entry name" value="GATA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00619">
        <property type="entry name" value="GATAZNFINGER"/>
    </dbReference>
    <dbReference type="SMART" id="SM00401">
        <property type="entry name" value="ZnF_GATA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57716">
        <property type="entry name" value="Glucocorticoid receptor-like (DNA-binding domain)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00344">
        <property type="entry name" value="GATA_ZN_FINGER_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50114">
        <property type="entry name" value="GATA_ZN_FINGER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0804">Transcription</keyword>
    <keyword evidence="5" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 8" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="GATA-type" evidence="10">
        <location>
            <begin position="79"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="domain" description="GATA-type" evidence="10">
        <location>
            <begin position="178"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="252"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="256"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="270"/>
            <end position="281"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00094"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50114"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="OBZ89396.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="396" mass="44161" checksum="990D119CB78A7463" modified="2016-11-30" version="1">MTVKSPFYNKPSTSTSVDSCHKCPLIQPSKTELSKNNVQQQQKVQSFSGFEQPTQSVSSSNNLFIEPSNSSVAKSDIGSTTVTSCSNCGTTTTPLWRRSPVGETICNACGLYLKARNTTRPVWLKRNAYKRPKQTIHPVTLAPRISPTPLLLLAPAPPQPTLLQIEPKSKEENEMPESSSALICANCQTTTTPLWRRDESGQPICNACGLYFKLHSIHRPITMKRSTIKRRKRVTAATMVTHQPVVIQYGATKRRPPTDDSARRTDHLRPLLPASPLRSSPDPIEPNAFQPTRYLPSPPMRPIKNNLACLLNPEIERQDRSLPSLPSPPLPYDEILPNKTEPAALNRLFQHGQPTQEVLEAHRIELKREVTNLTSLLSRTTAMLQNIDQVMANHHA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NM77</accession>
    <name>A0A1C7NM77_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">PHD-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">A0J61_01737</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000058">
        <property type="protein sequence ID" value="OBZ90222.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NM77"/>
    <dbReference type="STRING" id="101091.A0A1C7NM77"/>
    <dbReference type="InParanoid" id="A0A1C7NM77"/>
    <dbReference type="OrthoDB" id="79252at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019786">
        <property type="entry name" value="Zinc_finger_PHD-type_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001965">
        <property type="entry name" value="Znf_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019787">
        <property type="entry name" value="Znf_PHD-finger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00628">
        <property type="entry name" value="PHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00249">
        <property type="entry name" value="PHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01359">
        <property type="entry name" value="ZF_PHD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50016">
        <property type="entry name" value="ZF_PHD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="PHD-type" evidence="6">
        <location>
            <begin position="205"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="147"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="283"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="147"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="162"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="173"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="287"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="333"/>
            <end position="348"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OBZ90222.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="445" mass="50744" checksum="31A1F6070088E3FD" modified="2016-11-30" version="1">MSKHNNTKPCNRFKSDTVTISLPHRSVRHEERPVSQISLMAKQLKERLSMASQRLLPTEDVKQPLSSSDWPARKSLRHLQLLKQYLTFVSEEETASSDIVLRDRSIQLELSNQTNSIEPLTERQQSARLGATLIETLVHDPTGFEIHHGRQHDEGRHPIHRLDRRRPGRPPKTKMEEEKAEQTRVKRKSISQPRPSPQLKKKKELIRCICDSSSEEIGSMVQCDDCSRWLHLECLELNDDALEETFRCPSCFLSLGSLPNDSKLLSSITWRYAAQWKSQRLAAADSVSDDEEDEDEEMDDTIPPPLHDDDDGYSTDLPGPETPVDWPDVASESRFSTSQESEVTTPSEQLEPFFKEDNLEMTLDPGSLEILSRLAYLQSLDSVKKELFSPHAADVFLCENFTNDNIHLLTHQVPRFAPNTPPSSICSQDLSEFSFDSGPFWESLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NM89</accession>
    <name>A0A1C7NM89_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">A0J61_01717</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000057">
        <property type="protein sequence ID" value="OBZ90251.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NM89"/>
    <dbReference type="STRING" id="101091.A0A1C7NM89"/>
    <dbReference type="InParanoid" id="A0A1C7NM89"/>
    <dbReference type="OrthoDB" id="8117402at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="3">
        <location>
            <begin position="251"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="160"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="232"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="9"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="21"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="163"/>
            <end position="172"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OBZ90251.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="318" mass="34964" checksum="64C1281C571DC558" modified="2016-11-30" version="1">MYKGEEQRQQQQAVTLQVTVSPETTEPSSYHQPLTLPIDIPGSYSHSAFDNEALFASYRSSLGFGHQASPLDDPFFSSSSCPGLTTEDLTAGFDSLAVKSPSQPTTSPAQVGSPISLYTTNVISGSHSSSRLYYSPSFVNSPASHSPAISSCYLSPQYPSPSLAGSPSNRNHQFLYPPQPQLSRSTSPVPDDVILTTAEVNDLTTGIPISDFFTSVLNTITTDDLELFPSVVQPASPTQPRSIGKRKGKLHQCPHCQHTSNRANNMKEHILIHDPNRPKSHLCKLCRRAFARKHDMNRHYISCKKKEKSTKVKPQFTF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NMK1</accession>
    <name>A0A1C7NMK1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">G-protein coupled receptors family 1 profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_02249</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000082">
        <property type="protein sequence ID" value="OBZ89696.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NMK1"/>
    <dbReference type="InParanoid" id="A0A1C7NMK1"/>
    <dbReference type="OrthoDB" id="3210850at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38848">
        <property type="entry name" value="G-PROTEIN COUPLED RECEPTORS FAMILY 3 PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38848:SF3">
        <property type="entry name" value="G-PROTEIN COUPLED RECEPTORS FAMILY 3 PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="39"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="75"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="115"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="154"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="201"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="228"/>
            <end position="249"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ89696.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="293" mass="32887" checksum="B401431C9DA410A0" modified="2016-11-30" version="1">MYSPDQWEILAEVNSVACITIVSLIFGRKIAAMEGPVRYVQSLLFILYTFSWAFNLVACMLTSTNNGNYLSCVLTNFNSVILYTGTKIVLFLYFIEKAYIISAPKKSRFRSPLYLINLGLLLPSVAIISLQVMYRVTIVSDAYPYHCTVGFDMPASVVSLCYDVFLLALYMSIFIKFYSFPSDAQQNAYQATSLHMMAKRNAIACGASLVTSCVNFAIMIMTNGRERGLVASSVCALSVTIICCVIHWVTTHPIETQMNEKAFKGFNADKQIRLEIMQHQEVVVLTEVKHNRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NMV2</accession>
    <name>A0A1C7NMV2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Protein ERGIC-53</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">Lman1</name>
        <name evidence="11" type="ORF">A0J61_01640</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass type I membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000055">
        <property type="protein sequence ID" value="OBZ90300.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NMV2"/>
    <dbReference type="STRING" id="101091.A0A1C7NMV2"/>
    <dbReference type="InParanoid" id="A0A1C7NMV2"/>
    <dbReference type="OrthoDB" id="10265193at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030134">
        <property type="term" value="C:COPII-coated ER to Golgi transport vesicle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005793">
        <property type="term" value="C:endoplasmic reticulum-Golgi intermediate compartment"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005537">
        <property type="term" value="F:D-mannose binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006888">
        <property type="term" value="P:endoplasmic reticulum to Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051136">
        <property type="entry name" value="Intracellular_Lectin-GPT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005052">
        <property type="entry name" value="Lectin_leg"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12223:SF28">
        <property type="entry name" value="LECTIN, MANNOSE BINDING 1 LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12223">
        <property type="entry name" value="VESICULAR MANNOSE-BINDING LECTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03388">
        <property type="entry name" value="Lectin_leg-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51328">
        <property type="entry name" value="L_LECTIN_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 9" id="KW-0732">Signal</keyword>
    <keyword evidence="2 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008889794" evidence="9">
        <location>
            <begin position="20"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="458"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="domain" description="L-type lectin-like" evidence="10">
        <location>
            <begin position="38"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="255"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="381"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="270"/>
            <end position="290"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="OBZ90300.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="489" mass="55775" checksum="A31154E7B882FDF0" modified="2016-11-30" version="1">MKVHSIFFVSSILLQTCSAGLWGSKKEDPIQAEYRLADAPASMFDYKLSFKKNYYYNSSIPFWSTGGDIIKSEDFIRLSPSIPNTKGWIWSDIPNPYPEWEVEIGFKVKGNNLHGGRGLAFWYAKDPKETGPVFGSKDKWDGLSVWLDSANPRTHQQSTMILLNDGTLAFAAGEDPTKHMLGQCSISYRNSENPAFLKVTYKDQIITVALDNGSGAKDYRLCAQQSGIKLPTGYFFGISASSHTPADDHDVLSFETKQLNPPQKRQHPKRPLEEEKKKKGQDFKGIDEKQKKKIQEAEFQMKKLREAAEEDFQGEAAVTMATIYDTQRRAIEHLQIVQMQIEALGAPSPNDAISGNYKRINLDQLTMRDNKDNSYTNNDELKRITDQIRAESQKNENQIQEQDRKMKDIQVSLSRLEDALAALDRRILSHSNMIQTEMNKVNLHSVETKGTMSSLLKYIFYAFVAQFLFGIAGYLYWKLRVERNDKKFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NNF4</accession>
    <name>A0A1C7NNF4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Anthocyanidin 3-O-glucosyltransferase 7</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">GT7</name>
        <name evidence="6" type="ORF">A0J61_01262</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the UDP-glycosyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000038">
        <property type="protein sequence ID" value="OBZ90672.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NNF4"/>
    <dbReference type="STRING" id="101091.A0A1C7NNF4"/>
    <dbReference type="InParanoid" id="A0A1C7NNF4"/>
    <dbReference type="OrthoDB" id="5835829at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008194">
        <property type="term" value="F:UDP-glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03784">
        <property type="entry name" value="GT1_Gtf-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2000">
        <property type="entry name" value="Glycogen Phosphorylase B"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050271">
        <property type="entry name" value="UDP-glycosyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002213">
        <property type="entry name" value="UDP_glucos_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035595">
        <property type="entry name" value="UDP_glycos_trans_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48043">
        <property type="entry name" value="EG:EG0003.4 PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48043:SF145">
        <property type="entry name" value="FI06409P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00201">
        <property type="entry name" value="UDPGT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53756">
        <property type="entry name" value="UDP-Glycosyltransferase/glycogen phosphorylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00375">
        <property type="entry name" value="UDPGT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 3" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <keyword evidence="2 3 6" id="KW-0808">Transferase</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008889802" evidence="5">
        <location>
            <begin position="26"/>
            <end position="551"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="513"/>
            <end position="541"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003718"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OBZ90672.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="551" mass="61967" checksum="023A5F0E613DC622" modified="2016-11-30" version="1">MKTNLEKALTAFLLAIALLLRSAHATYTFEPTYHDNGLKNIAFFAVWGGTSHSVWVLNICDELGKRGHNVSYLTTDEQAKYGRPYQHVNTVAIGPGNYRMKDVGDNSIIKNLGRIGFMLRAFDMLYINYERGMKINYFLANDIDVAICDHFGEACVDAATTLSIPYIVTSSMDFTKDSSTPYVRTDVSSLDEPTTEFQSLATRFYNGFIVPMKFVKIMFPTLRKLNDRKRAIGIDSKITDPSVKWQNALKLVNSAHGFSAPRPVGPLVELVGPIIPREYPSLTESIKAFLDQHKRVAYIAFGQYSTPNKHDVNLVLTSLLESIEKDYIDGFIWAAVSYDHLLPEAVTTSSGTVYPTEAILNQTNSHARMFSWAPQVAILTHPSLHLFVSHGGLGSCYESIYAGKRMIMYPFFGDQPINSHMIEQNGLGAILKYDYTVEESVNTIKRVALDQDGEIIRNVKRFQSLVQVRSKHSVVRGADAVEEVVYTHKNGVLPHRISADHRMSFIKSHNIDIYSIFIMLTFVILRTATFAVTRFVSYLLALKAKNKIKTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NNM2</accession>
    <name>A0A1C7NNM2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">pyridoxal 5'-phosphate synthase (glutamine hydrolyzing)</fullName>
            <ecNumber evidence="3">4.3.3.6</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">PDX1_1</name>
        <name evidence="12" type="ORF">A0J61_01343</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>aldehydo-D-ribose 5-phosphate + D-glyceraldehyde 3-phosphate + L-glutamine = pyridoxal 5'-phosphate + L-glutamate + phosphate + 3 H2O + H(+)</text>
            <dbReference type="Rhea" id="RHEA:31507"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58273"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
            <dbReference type="EC" id="4.3.3.6"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Cofactor biosynthesis; pyridoxal 5'-phosphate biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the PdxS/SNZ family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.3.3.6" evidence="3"/>
    <dbReference type="EMBL" id="LUGH01000041">
        <property type="protein sequence ID" value="OBZ90608.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NNM2"/>
    <dbReference type="FunCoup" id="A0A1C7NNM2">
        <property type="interactions" value="177"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NNM2"/>
    <dbReference type="InParanoid" id="A0A1C7NNM2"/>
    <dbReference type="OrthoDB" id="1660966at2759"/>
    <dbReference type="UniPathway" id="UPA00245"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036381">
        <property type="term" value="F:pyridoxal 5'-phosphate synthase (glutamine hydrolysing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006520">
        <property type="term" value="P:amino acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042823">
        <property type="term" value="P:pyridoxal phosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008615">
        <property type="term" value="P:pyridoxine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd04727">
        <property type="entry name" value="pdxS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.70:FF:000001">
        <property type="entry name" value="Pyridoxine biosynthesis protein PDX1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01824">
        <property type="entry name" value="PdxS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001852">
        <property type="entry name" value="PdxS/SNZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033755">
        <property type="entry name" value="PdxS/SNZ_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011060">
        <property type="entry name" value="RibuloseP-bd_barrel"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003215">
        <property type="entry name" value="PRK04180.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00343">
        <property type="entry name" value="pyridoxal 5'-phosphate synthase lyase subunit PdxS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31829">
        <property type="entry name" value="PYRIDOXAL 5'-PHOSPHATE SYNTHASE SUBUNIT SNZ1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31829:SF0">
        <property type="entry name" value="PYRIDOXAL 5'-PHOSPHATE SYNTHASE SUBUNIT SNZ1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01680">
        <property type="entry name" value="SOR_SNZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF029271">
        <property type="entry name" value="Pdx1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51366">
        <property type="entry name" value="Ribulose-phoshate binding barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01235">
        <property type="entry name" value="PDXS_SNZ_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51129">
        <property type="entry name" value="PDXS_SNZ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0456">Lyase</keyword>
    <keyword evidence="4" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 8" id="KW-0704">Schiff base</keyword>
    <feature type="domain" description="PdxS/SNZ N-terminal" evidence="11">
        <location>
            <begin position="24"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="active site" description="Schiff-base intermediate with D-ribose 5-phosphate" evidence="8">
        <location>
            <position position="98"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="41"/>
        </location>
        <ligand>
            <name>D-ribose 5-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:78346"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="170"/>
        </location>
        <ligand>
            <name>D-ribose 5-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:78346"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="182"/>
        </location>
        <ligand>
            <name>D-glyceraldehyde 3-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="231"/>
        </location>
        <ligand>
            <name>D-ribose 5-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:78346"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="252"/>
            <end position="253"/>
        </location>
        <ligand>
            <name>D-ribose 5-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:78346"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012084"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR029271-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR029271-51"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF01680"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="OBZ90608.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="311" mass="33289" checksum="C604C665D0F24318" modified="2016-11-30" version="1">MASAFTVPANLHSNKAEENGAESFSIKAGLAQMLKGGVIMDVIDAEQARIAEEAGACAVMALERVPADIRKNGGVARMSDPKMIKEIIEAVTIPVMAKVRIGHFVEAQIIESIGVDYIDESEVLTPADESNHINKHNFKVPYVCGAKNLGEALRRINEGAAMIRTKGEAGTGNVVEAVRHIRTVNSEIRRASAMTDEELYAYAKDLQAPYALLKETAKLGRLPVVNFAAGGVATPADAALMMQLGCDGVFVGSGIFKSGDPAKRARAIVQAVTHYNDAKVLAEVSEDLGEAMVGINLDQLPEDQKYAKRGW</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NNR1</accession>
    <name>A0A1C7NNR1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">UDP-glucuronosyltransferase 2B37</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">Ugt2b37</name>
        <name evidence="5" type="ORF">A0J61_01423</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the UDP-glycosyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000045">
        <property type="protein sequence ID" value="OBZ90519.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NNR1"/>
    <dbReference type="STRING" id="101091.A0A1C7NNR1"/>
    <dbReference type="InParanoid" id="A0A1C7NNR1"/>
    <dbReference type="OrthoDB" id="5835829at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008194">
        <property type="term" value="F:UDP-glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03784">
        <property type="entry name" value="GT1_Gtf-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2000">
        <property type="entry name" value="Glycogen Phosphorylase B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050271">
        <property type="entry name" value="UDP-glycosyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002213">
        <property type="entry name" value="UDP_glucos_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035595">
        <property type="entry name" value="UDP_glycos_trans_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48043">
        <property type="entry name" value="EG:EG0003.4 PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48043:SF145">
        <property type="entry name" value="FI06409P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00201">
        <property type="entry name" value="UDPGT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53756">
        <property type="entry name" value="UDP-Glycosyltransferase/glycogen phosphorylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00375">
        <property type="entry name" value="UDPGT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 3" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3 5" id="KW-0808">Transferase</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="264"/>
            <end position="287"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003718"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OBZ90519.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="296" mass="34218" checksum="2623E44C9113821B" modified="2016-11-30" version="1">MINSFWGIESPRPVGPLVEYVGPIINAVYDPLDSKLSKFMDTHQRVVYIAFGQMYNPSKKEFEVLLTSLVEAYESDYLNGFIWSLSMKSRHNLPEQIITRSGRVYKVNDLLQNHADLRFETWSPQFAILQHPHCRLFISHGGASSIHESLYNGVPLLLHPFTSDQPQNANSIVASGVALQVDRKKYNVTDTFEKLSEILLDKDQKFATQMKSMQALVQIRSRRKVYAADIIEEVLYSVRSGDDLWYRRQVNERMPWYKATNWDINMFGVCIIAFVFSGVYAVIRFVFVSHKKHKVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NP39</accession>
    <name>A0A1C7NP39_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Chromodomain-helicase-DNA-binding protein 9</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">CHD9</name>
        <name evidence="13" type="ORF">A0J61_01068</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000030">
        <property type="protein sequence ID" value="OBZ90875.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NP39"/>
    <dbReference type="InParanoid" id="A0A1C7NP39"/>
    <dbReference type="OrthoDB" id="5857104at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008094">
        <property type="term" value="F:ATP-dependent activity, acting on DNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd17995">
        <property type="entry name" value="DEXHc_CHD6_7_8_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00167">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18793">
        <property type="entry name" value="SF2_C_SNF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10810">
        <property type="entry name" value="Tandem AAA-ATPase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016197">
        <property type="entry name" value="Chromo-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000953">
        <property type="entry name" value="Chromo/chromo_shadow_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023780">
        <property type="entry name" value="Chromo_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023779">
        <property type="entry name" value="Chromodomain_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056342">
        <property type="entry name" value="HTH_CHD6-9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001005">
        <property type="entry name" value="SANT/Myb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038718">
        <property type="entry name" value="SNF2-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049730">
        <property type="entry name" value="SNF2/RAD54-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000330">
        <property type="entry name" value="SNF2_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45623">
        <property type="entry name" value="CHROMODOMAIN-HELICASE-DNA-BINDING PROTEIN 3-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45623:SF11">
        <property type="entry name" value="KISMET, ISOFORM C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00385">
        <property type="entry name" value="Chromo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23078">
        <property type="entry name" value="HTH_CHD6-9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00176">
        <property type="entry name" value="SNF2-rel_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00298">
        <property type="entry name" value="CHROMO"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54160">
        <property type="entry name" value="Chromo domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00598">
        <property type="entry name" value="CHROMO_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50013">
        <property type="entry name" value="CHROMO_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="13" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="13" id="KW-0347">Helicase</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="7" id="KW-0804">Transcription</keyword>
    <keyword evidence="6" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Chromo" evidence="10">
        <location>
            <begin position="384"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="11">
        <location>
            <begin position="488"/>
            <end position="663"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="12">
        <location>
            <begin position="800"/>
            <end position="952"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="168"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="200"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1076"/>
            <end position="1113"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1312"/>
            <end position="1341"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1370"/>
            <end position="1398"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1459"/>
            <end position="1487"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1626"/>
            <end position="1651"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1663"/>
            <end position="1763"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="9">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="173"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="203"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="221"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="9">
        <location>
            <begin position="237"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="260"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="1332"/>
            <end position="1341"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="1388"/>
            <end position="1398"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="1668"/>
            <end position="1677"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="1718"/>
            <end position="1731"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="1736"/>
            <end position="1749"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50013"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="OBZ90875.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="1763" mass="203940" checksum="2B7E64D7AFAE8D0F" modified="2016-11-30" version="1">MAHQGHHHHTQAGGEADNMPPPFGEQAFDQEDLLSTFIGQNGFGQSLFVDTQQTNGLDLYHHHHQSPNNSHFTADTTHFITQSPRNPSSFVNLIQFNPSEPESLGSFSPSPLPSVRLQGAYDGVPISGSNQQLRMFNMANQLQGFPSTMHQPSYSPLYQQQVQMQQHRIQTQPNSFQHSMYQRTSTALPQQQQIMFQQMPSQLVSSPQQQHHSMLSHHYHPQQQHRQSQQASQPRTTTKRPASKRSGRAASKRKVKYQESSEEEEEDVDHLSDEEPPQAESDSDFEDQPRSSKAKNTSAAATEVPVVMIPMPTRIFEKMLDYRLNPTTQQPELLVKYKYSSYHHAEWVPKEKIEAEHLGKHRVKKFLTKWHQDGQRGEDFSEYLKVDRVIDEGELVDPQTGEPTLYYLVKWSGLFYDASTWESEEAVQKMDMSKIVEYQRHRVISQEKLPNPPSRHEFPPFIKYEQSQKYKFGNELRPXQLEGLNWMRFCYYNARSCILADEMGLGKTVQSVAFLNDLYYQLSIRGPFLIVAPLSTIPHWERAFRAWTDLNVIDYRGSVLSRDLLVETEFYYKDIQNKPIPNRYKFDVLITTYEMASAGAPHIKDITWRCAVFDEAHRLKNKQSKVGEILKSFSIDHKLLLTGTPLQNNLDELYSLLNFMQPELFNNERAFFAEYGNLQTALEVEKLQSLLRPIMLRRFKEDVEKSIPVKEETVIEVELTNSQKKWYRAILEKNFSFLKKGAKSNKEMPQLRNVMMQLRKCCIHPYLLEGAEEVIVNENHARTIHDQFKCLIDASGKLVLIDKLLRKLFEGNHKVLIFSQFTSCLDILSDYLRGRQYPHERIDGSIPGEQRQAAIDRFSTLPIDQSFVFLLCTKAGGVGINLTAADTCIIFDSDWNPQNDLQAQARCHRIGQTKPVQVYRLICRNTYEKDMFDRAGMKLGLDKAVMQRMNASSHQAVEEDTQHVSKNELNRKEIEDLLKKGAYGAILDDEESAQFCEEDIDQILERRTTVIRHEGNEKGSVFSKATFASSAGHQVELDDPDFWDKWATKANVDVQDMQDENELIVYEPRRRRQVQRFGARAADGTYSDNDHADDSDAYEDESERSRKRDTPRPWTLSEKTKYERKLMIYGYGPWHQMQAHFPRRSEKDLKAATRCLMRKIKHVIEGQTEEDRKLLQDIEFILSNDAQDDDPGDETVPYKHANKKQIAEFRSFLIQAPADYVEHIERKGRNFLLRIQMLHMVRDRIVPKDWEEAKQLVIPKVTGSLPCDWWGESEDRDLLLGICKHGYQQYLTMRKDKEFCFFGKRFDDSKAGTLQEDDDEPANEKIQDDSSELQQESENSTVYVWPSKADIGMRLRRIIAAFLREQGVENRRRRVNQEQSRPSRSRSRATDSGHRWQKKNRSDFMRTILSFGIETVQGDPNIRWDRFREISGLEKRSDASLDQYYYKFYAACKEIMRREKEEEEEEEGAVDQKSRESSEEPASTPVESEELELVNIIPYDKARRALKRIEQMKMIREHVIVDPDFDHAITKARKTSGLPPWWEVPLHDKALLEGICKHGIGRHDLMITDPELPFQQIVKDTTGQSDLAQADPASISAILLQIAWPKELVIARRIDALCSLILRPKPEKRSRGSRKQKTIHPEPIAARPMTGGKTILPFLSSSLSVSSPHTQSTAGSTDSEDENEDRRKQARYELYQQQEERAPTKPLKSQGFRYPLPVNTTPSNYITQRPSSHLDEEMEEGEITDEDDTDSMHKSSSSSSFAY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NPK8</accession>
    <name>A0A1C7NPK8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">MMS19 nucleotide excision repair protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">mms19_1</name>
        <name evidence="4" type="ORF">A0J61_00897</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Key component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into apoproteins specifically involved in DNA metabolism and genomic integrity. In the CIA complex, MMS19 acts as an adapter between early-acting CIA components and a subset of cellular target iron-sulfur proteins.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the MET18/MMS19 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000024">
        <property type="protein sequence ID" value="OBZ91052.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NPK8"/>
    <dbReference type="STRING" id="101091.A0A1C7NPK8"/>
    <dbReference type="InParanoid" id="A0A1C7NPK8"/>
    <dbReference type="OrthoDB" id="342900at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097361">
        <property type="term" value="C:cytosolic [4Fe-4S] assembly targeting complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016226">
        <property type="term" value="P:iron-sulfur cluster assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051604">
        <property type="term" value="P:protein maturation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039920">
        <property type="entry name" value="MMS19"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024687">
        <property type="entry name" value="MMS19_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12891">
        <property type="entry name" value="DNA REPAIR/TRANSCRIPTION PROTEIN MET18/MMS19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12891:SF0">
        <property type="entry name" value="MMS19 NUCLEOTIDE EXCISION REPAIR PROTEIN HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12460">
        <property type="entry name" value="MMS19_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0227">DNA damage</keyword>
    <keyword evidence="2" id="KW-0234">DNA repair</keyword>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MMS19 C-terminal" evidence="3">
        <location>
            <begin position="303"/>
            <end position="730"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009340"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU367072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF12460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OBZ91052.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="774" mass="87368" checksum="9F41601C36294116" modified="2016-11-30" version="1">MLSHIIKRCDQRDLDESTNAIETLTACIPIYPVNDFFAIGAKLLNAIKIELFNDDPDPSLKEPSLEAIKAIAKVTTVDPKRESDALSVLKYLVNDCIQLLSELNEGNVKPSSLVLRAIASASPFAYCLVENAVMPKLLRQYEEKIDISDRYLLLCTMIALIQARKIVYGTSDRSEEFDPNETNHSSILFSHKRRIIDIFVFIIKQPIEHTEVHVMATLGLGQLCVLKSYLRKDERTFCVQELSKILERENDRKLRASVETSLSEIATLDSTLISNITMPILMKCLPEFSSNEGSSLTDLKLTFESVRNLCVSFCIYRTVEHDLLQKFMNTCSHNKDQKYAFEIISTLLKLIQARENESRLSECAKTLVHNLISSTASAAKDATIAPGDAIILNSDIVETISLIVQAVFRNMNEEEQKEYAIKIFKYFKDGDLSEFGMIFNNDISFCPLNANTSNAQAACVPIFAAVVSAAHFNELLPIESDAYFLDFVVNEALRTTCEIQLVSFCRILASILNKWKNKDRDNYIQAHEKKLKFCVENENSTSALALYIWITKALVIQSHKDYEEMTDMILHWMNHPVIGKKASYGFDVLTINDLLCLNKQCFADVSLLYKQKFADYALPKLLDVFSKSITKDQRSNSLVATVCLLKNMPNSILIDQFPPLIHLLIESLSLPDNVLKLSTLSIFQSALSDATQCIEKHTGTLLSKLLLLIKPEEKSMNVRAAALRCIGLIPVKVSRDVTLPLAKDTIKTLAIALDDKKRIVRRQAVECREHWYCV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NPZ3</accession>
    <name>A0A1C7NPZ3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">UDP-N-acetylglucosamine diphosphorylase</fullName>
            <ecNumber evidence="3">2.7.7.23</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">UAP1</name>
        <name evidence="8" type="ORF">A0J61_00752</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>N-acetyl-alpha-D-glucosamine 1-phosphate + UTP + H(+) = UDP-N-acetyl-alpha-D-glucosamine + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:13509"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:46398"/>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
            <dbReference type="ChEBI" id="CHEBI:57776"/>
            <dbReference type="EC" id="2.7.7.23"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Nucleotide-sugar biosynthesis; UDP-N-acetyl-alpha-D-glucosamine biosynthesis; UDP-N-acetyl-alpha-D-glucosamine from N-acetyl-alpha-D-glucosamine 1-phosphate: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the UDPGP type 1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.23" evidence="3"/>
    <dbReference type="EMBL" id="LUGH01000019">
        <property type="protein sequence ID" value="OBZ91181.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NPZ3"/>
    <dbReference type="FunCoup" id="A0A1C7NPZ3">
        <property type="interactions" value="175"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NPZ3"/>
    <dbReference type="InParanoid" id="A0A1C7NPZ3"/>
    <dbReference type="OrthoDB" id="532420at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003977">
        <property type="term" value="F:UDP-N-acetylglucosamine diphosphorylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006048">
        <property type="term" value="P:UDP-N-acetylglucosamine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd04193">
        <property type="entry name" value="UDPGlcNAc_PPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.550.10:FF:000075">
        <property type="entry name" value="Probable UDP-N-acetylglucosamine pyrophosphorylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="entry name" value="Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039741">
        <property type="entry name" value="UDP-sugar_pyrophosphorylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002618">
        <property type="entry name" value="UDPGP_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11952:SF2">
        <property type="entry name" value="LD24639P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11952">
        <property type="entry name" value="UDP- GLUCOSE PYROPHOSPHORYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01704">
        <property type="entry name" value="UDPGP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="47"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005208"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010401"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012457"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00048493"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OBZ91181.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="504" mass="55712" checksum="4E680BBCFCA9A17E" modified="2016-11-30" version="1">MTTQPTTLPINESELQALKTRFEANGQGHVFHFFDNLEVEQKAQLINQLLEIDVERLNQIYQKAIEAAEAAATDKETQFEPLPASVFESVPKASAEKIREWETIGLSHIAKGQVAVILMAGGQGTRLGSSDPKGCYDINLPSKKSLFQLQAERILRLQDIARQYTKPGKDCIIPWYIMTSGPTHAPTYNFFEKNNFFGLKKENVIFFEQGVLPCLTMDGKIILEGKDKVAVAPDGNGGIYAAVQNKGVIASLKERGILYSHCYCVDNCLARVADPVFLGYSISKGTDCGVKVVSKTAPEEPVGVVCVRDGKYGVVEYSEISQELSEKRQDDGSLAFCAANIANHFFSTEFLERVPSFASQLEYHIAKKKIKYIDLETGEVIAPKSNSGMKLECFVFDVFPFAQNFSVLEVDRKDDFSPLKNAPGSGADCPETSRRDIVAQHVRFIEAAGGKVVGEHEGDFEKLEFELSSWVSYAGEGLVEYVSGKTITTPAIIETKEDLIRFAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NQ02</accession>
    <name>A0A1C7NQ02_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Protochlorophyllide reductase B, chloroplastic</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">PORB</name>
        <name evidence="3" type="ORF">A0J61_01424</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000045">
        <property type="protein sequence ID" value="OBZ90526.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NQ02"/>
    <dbReference type="STRING" id="101091.A0A1C7NQ02"/>
    <dbReference type="InParanoid" id="A0A1C7NQ02"/>
    <dbReference type="OrthoDB" id="542013at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24320">
        <property type="entry name" value="RETINOL DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24320:SF152">
        <property type="entry name" value="SHORT-CHAIN DEHYDROGENASE_REDUCTASE FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ90526.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="301" mass="33638" checksum="40654D92361DDC82" modified="2016-11-30" version="1">MSDTRLVVFITGATVGLGRLTAKKCIGAGHTVVITGRTEQKLKDAKQWILKDTPQYEENLHGLVMDLLDTPSMKKAVEKLGALGLPAIDVIVHNAGGTRREFSQIHGYESTIYMNAVAPLLLNQMLLPFIEKSQHPSKRIIFIASQIHNPEINGGGGGESRKIPKDVQVADFKGDKKNWDSMKYYKMSKLAVIWIAFSLAKKYPSIKSIAICPGFVPTTELARNSSYVLRMAMKYAISKFNFATTEDDSTDFYMFHITNPDIKTGAYYEKTEPATPSEDALNITKQEEFYQLAEKTVEENM</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NQM2</accession>
    <name>A0A1C7NQM2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">37S ribosomal protein mrp4, mitochondrial</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">mrp4</name>
        <name evidence="5" type="ORF">A0J61_01250</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uS2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000037">
        <property type="protein sequence ID" value="OBZ90716.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NQM2"/>
    <dbReference type="FunCoup" id="A0A1C7NQM2">
        <property type="interactions" value="264"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NQM2"/>
    <dbReference type="InParanoid" id="A0A1C7NQM2"/>
    <dbReference type="OrthoDB" id="2320368at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005763">
        <property type="term" value="C:mitochondrial small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01425">
        <property type="entry name" value="RPS2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10490">
        <property type="entry name" value="Glucose-6-phosphate isomerase like protein, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00291_B">
        <property type="entry name" value="Ribosomal_uS2_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001865">
        <property type="entry name" value="Ribosomal_uS2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005706">
        <property type="entry name" value="Ribosomal_uS2_bac/mit/plastid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018130">
        <property type="entry name" value="Ribosomal_uS2_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023591">
        <property type="entry name" value="Ribosomal_uS2_flav_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01011">
        <property type="entry name" value="rpsB_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12534">
        <property type="entry name" value="30S RIBOSOMAL PROTEIN S2 PROKARYOTIC AND ORGANELLAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12534:SF0">
        <property type="entry name" value="SMALL RIBOSOMAL SUBUNIT PROTEIN US2M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00318">
        <property type="entry name" value="Ribosomal_S2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00395">
        <property type="entry name" value="RIBOSOMALS2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52313">
        <property type="entry name" value="Ribosomal protein S2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00962">
        <property type="entry name" value="RIBOSOMAL_S2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 5" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="268"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="274"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="284"/>
            <end position="295"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OBZ90716.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="295" mass="32526" checksum="EC719E22247E0F5B" modified="2016-11-30" version="1">MASRALYKSAVLRGGLAARQNLFRSFSTSTFVRQTADTTNNDQITPESLVPPSSTPLKQSIRQAVTIAATEPITPYNLTISKLMAAGLHLGHSTSLWEPTTLPFIFGTREGISIINLEHTLVYLRRACNVAREVSLRGGSILFVGTRPGFQDLTIDAARNCDGFHVSSKWIPGTLTNRHQVLGRHAPPDPEDPGRPPKTYKPDLIVLLNPLEHKIAIAEAQLNNIPIIAITDTDYDPRLVTYPIPANDDSIRGVELVAKVLSAAAKDGLHKRKQMLDQREKEKKLLKKQHSGSRH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NQN0</accession>
    <name>A0A1C7NQN0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">phenylalanine--tRNA ligase</fullName>
            <ecNumber evidence="5">6.1.1.20</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="14">Phenylalanyl-tRNA synthetase beta subunit</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">A0J61_01221</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="15">
            <text>tRNA(Phe) + L-phenylalanine + ATP = L-phenylalanyl-tRNA(Phe) + AMP + diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:19413"/>
            <dbReference type="Rhea" id="RHEA-COMP:9668"/>
            <dbReference type="Rhea" id="RHEA-COMP:9699"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58095"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78531"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.20"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="4">Tetramer of two alpha and two beta subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.20" evidence="5"/>
    <dbReference type="EMBL" id="LUGH01000036">
        <property type="protein sequence ID" value="OBZ90726.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NQN0"/>
    <dbReference type="FunCoup" id="A0A1C7NQN0">
        <property type="interactions" value="769"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NQN0"/>
    <dbReference type="InParanoid" id="A0A1C7NQN0"/>
    <dbReference type="OrthoDB" id="1698572at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009328">
        <property type="term" value="C:phenylalanine-tRNA ligase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004826">
        <property type="term" value="F:phenylalanine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990825">
        <property type="term" value="F:sequence-specific mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006432">
        <property type="term" value="P:phenylalanyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd00769">
        <property type="entry name" value="PheRS_beta_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.930.10:FF:000059">
        <property type="entry name" value="phenylalanine--tRNA ligase beta subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.50.40.10:FF:000002">
        <property type="entry name" value="phenylalanine--tRNA ligase beta subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.56.10:FF:000004">
        <property type="entry name" value="Phenylalanyl-tRNA synthetase, beta subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.56.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="entry name" value="Bira Bifunctional Protein, Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.40.10">
        <property type="entry name" value="Phenylalanyl-trna Synthetase, Chain B, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005146">
        <property type="entry name" value="B3/B4_tRNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009061">
        <property type="entry name" value="DNA-bd_dom_put_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045060">
        <property type="entry name" value="Phe-tRNA-ligase_IIc_bsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004531">
        <property type="entry name" value="Phe-tRNA-synth_IIc_bsu_arc_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020825">
        <property type="entry name" value="Phe-tRNA_synthase-like_B3/B4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041616">
        <property type="entry name" value="PheRS_beta_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040659">
        <property type="entry name" value="PhetRS_B1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005147">
        <property type="entry name" value="tRNA_synthase_B5-dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00471">
        <property type="entry name" value="pheT_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10947:SF0">
        <property type="entry name" value="PHENYLALANINE--TRNA LIGASE BETA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10947">
        <property type="entry name" value="PHENYLALANYL-TRNA SYNTHETASE BETA CHAIN AND LEUCINE-RICH REPEAT-CONTAINING PROTEIN 47"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03483">
        <property type="entry name" value="B3_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03484">
        <property type="entry name" value="B5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18262">
        <property type="entry name" value="PhetRS_B1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17759">
        <property type="entry name" value="tRNA_synthFbeta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00873">
        <property type="entry name" value="B3_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00874">
        <property type="entry name" value="B5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="Class II aaRS and biotin synthetases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56037">
        <property type="entry name" value="PheT/TilS domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46955">
        <property type="entry name" value="Putative DNA-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51483">
        <property type="entry name" value="B5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="13" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7 17" id="KW-0436">Ligase</keyword>
    <keyword evidence="11" id="KW-0460">Magnesium</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="B5" evidence="16">
        <location>
            <begin position="302"/>
            <end position="380"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012814"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00033189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00049255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS51483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="OBZ90726.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="604" mass="68640" checksum="4EC411D38912C7FE" modified="2016-11-30" version="1">MPTVNIDKQRLFEALEREYTSQEFFELCFRFGIELEEDTSEREIVEKDTSKSAEEVPERPVLKIDIPANRYDLLCQEGLARALRIFEGKSNPPVFKAVKPADGKLEQIRVLESTQQIRPYIVGAILRNITFTAENYASFIDLQDKLHNNICRKRTLASMGTHDLDTIKGPFTYEALPHKDIKFVPLNKDVEVDGDELMELYSEDRNLGKFLHIIRDSPVYPVVFDANRTVCSLPPIINSDHSKITLNTKNVLIEITATDEHKASTVLNTLVAMFSEYCAEPFTVEPVEIVYPDNTVKVYPQMEPRDASAKVDYINSCTGLELPGDEICRLLNRMSLDATIDPKDNNQVLVKVPPTRWDILHACDIMEDVAISYGYDNLPKKMPNVNTFASALPLNKLSDSVRRELAMSGFTEVAPLILCSHDENFKFLNRKDDGTTAIQLANPKTAEYQVVRTSLLPGILKTLNSNKKLPLPLKTFEVSDVGFKDESRDRRTRNERHVCATYTSKTSGFEVIHGLLERIMNMLSTKRIAKSDNKSLGYWIEESEDATYFPDRSAYIFLRYLDAETNERKSAQIGSFGILHPVVLQNFELTNPTTALEFNLEPFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-06-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NQP1</accession>
    <name>A0A1C7NQP1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_00532</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000012">
        <property type="protein sequence ID" value="OBZ91412.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NQP1"/>
    <dbReference type="InParanoid" id="A0A1C7NQP1"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ91412.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="130" mass="15304" checksum="5D962E377D04BEBB" modified="2016-11-30" version="1">MGTVNSIDDPYAYYNSNYISELDRYYRRYYPQYYNSQPPYYPSTNAAASYYSNSLYPQPYYPQIPNSYSAPGYNNMMYNSLLPQNYYSSPYSFNSSNMYMNSMPTSFQGGAGGNMYGYPYYPNYPQRTYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-06-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NQT9</accession>
    <name>A0A1C7NQT9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_00513</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000011">
        <property type="protein sequence ID" value="OBZ91463.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NQT9"/>
    <dbReference type="InParanoid" id="A0A1C7NQT9"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ91463.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="119" mass="13749" checksum="E037E8E8AB216CE8" modified="2016-11-30" version="1">MINTALWFKKKYPGNRHQNNQDTKLSTISFNMEQGHLLPKDEVTMQKSLGAEAMEKYISQTKNKAIRIKKQHSASSRIGCSLLISTWTQNRPDNLRKLCHQTGALSWHKPLSDLNRETR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NR69</accession>
    <name>A0A1C7NR69_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Protein arginine N-methyltransferase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">PMRT15</name>
        <name evidence="12" type="ORF">A0J61_00326</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the class I-like SAM-binding methyltransferase superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000007">
        <property type="protein sequence ID" value="OBZ91592.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NR69"/>
    <dbReference type="FunCoup" id="A0A1C7NR69">
        <property type="interactions" value="903"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NR69"/>
    <dbReference type="InParanoid" id="A0A1C7NR69"/>
    <dbReference type="OrthoDB" id="1368803at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071521">
        <property type="term" value="C:Cdc42 GTPase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051286">
        <property type="term" value="C:cell tip"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990463">
        <property type="term" value="C:lateral cortical node"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016274">
        <property type="term" value="F:protein-arginine N-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071470">
        <property type="term" value="P:cellular response to osmotic stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061246">
        <property type="term" value="P:establishment or maintenance of bipolar cell polarity regulating cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:1903359">
        <property type="term" value="P:lateral cortical node assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:1903360">
        <property type="term" value="P:protein localization to lateral cortical node"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:2000100">
        <property type="term" value="P:regulation of establishment or maintenance of bipolar cell polarity regulating cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.150:FF:000149">
        <property type="entry name" value="Protein arginine N-methyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.150">
        <property type="entry name" value="Divalent-metal-dependent TIM barrel enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.160.11">
        <property type="entry name" value="Hnrnp arginine n-methyltransferase1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025799">
        <property type="entry name" value="Arg_MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007857">
        <property type="entry name" value="Arg_MeTrfase_PRMT5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035075">
        <property type="entry name" value="PRMT5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035248">
        <property type="entry name" value="PRMT5_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035247">
        <property type="entry name" value="PRMT5_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10738">
        <property type="entry name" value="PROTEIN ARGININE N-METHYLTRANSFERASE 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10738:SF0">
        <property type="entry name" value="PROTEIN ARGININE N-METHYLTRANSFERASE 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05185">
        <property type="entry name" value="PRMT5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17286">
        <property type="entry name" value="PRMT5_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17285">
        <property type="entry name" value="PRMT5_TIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF015894">
        <property type="entry name" value="Skb1_MeTrfase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51678">
        <property type="entry name" value="SAM_MT_PRMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 4 8" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4 6" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2 4 8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PRMT5 TIM barrel" evidence="10">
        <location>
            <begin position="36"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="domain" description="PRMT5 arginine-N-methyltransferase" evidence="9">
        <location>
            <begin position="290"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="domain" description="PRMT5 oligomerisation" evidence="11">
        <location>
            <begin position="458"/>
            <end position="637"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor/acceptor" evidence="5">
        <location>
            <position position="426"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor/acceptor" evidence="5">
        <location>
            <position position="435"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="317"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="326"/>
            <end position="327"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="383"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="410"/>
            <end position="411"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="site" description="Critical for specifying symmetric addition of methyl groups" evidence="7">
        <location>
            <position position="320"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRNR" id="PIRNR015894"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR015894-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR015894-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR015894-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF05185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF17285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF17286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="OBZ91592.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="639" mass="73001" checksum="CF8E77E4B390A3AA" modified="2016-11-30" version="1">MTEAVDSSRFCSVGLLTTECYDDVGNFISQAEEAGHDFVVSPLTHPIFRRVLNENKQVEKQTHANWKDRPVFDRNDLVFKSAEWSTRAMGLVANWIQLDSTDSEIRLCSEIALRQEIDWTCHISLSGLILPALPKGSLYNTARVINDAVKSMTYTQFAVRVPLLEKSNIQGNVSWKQWNRFRTLTEHNTKIHVALEITSELPSDEKLLNLWLAEPVKTVIVPGEIFVSNSKGYPVLPKPHQRFIQKLMDKMKPDIVVTVPPTQLHKMATPSSYSEYINYLNRHLPPLNEVEQFAAGYHDYLQAPLQPLMDNLENQTYEVFEKDPIKYQQYEKAVYQALLDRVEPNSDYVTTIMVVGAGRGPLVNCCLRASEKSERKVHIYALEKNHNAFVTLQNAKADIWGDRVTLVFADMRKWSPPSQCDILVSELLGSFGDNELSPECLDGAQKFIKEDGISIPASYTAFASPLASTRLHNNVAAYKDLEHFETPYVVMFQQVCELASPEPLWTFAHPNKQDIPDRGDPLNNLHNKRYSHVEFKVKHDMVMHGIAGYFESVLYKDVMISIHPKTHSPGMFSWFPIYFPLRTPVQVPQNATVSFDFWRLTDDKKVWYEWTASVHGSHGEEMTVLPIHNVNGRSYWVGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NRE7</accession>
    <name>A0A1C7NRE7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">SET domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">A0J61_00251</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Chromosome</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000005">
        <property type="protein sequence ID" value="OBZ91673.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NRE7"/>
    <dbReference type="STRING" id="101091.A0A1C7NRE7"/>
    <dbReference type="InParanoid" id="A0A1C7NRE7"/>
    <dbReference type="OrthoDB" id="6627536at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005694">
        <property type="term" value="C:chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042799">
        <property type="term" value="F:histone H4K20 methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd10524">
        <property type="entry name" value="SET_Suv4-20-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.1700">
        <property type="entry name" value="Histone-lysine N-methyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.270.10">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041938">
        <property type="entry name" value="Hist-Lys_N-MTase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001214">
        <property type="entry name" value="SET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046341">
        <property type="entry name" value="SET_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039977">
        <property type="entry name" value="Suv4-20/Set9"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12977:SF4">
        <property type="entry name" value="HISTONE-LYSINE N-METHYLTRANSFERASE KMT5B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12977">
        <property type="entry name" value="SUPPRESSOR OF VARIEGATION 4-20-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00856">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00317">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82199">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50280">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="3" id="KW-0158">Chromosome</keyword>
    <keyword evidence="4" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="SET" evidence="10">
        <location>
            <begin position="110"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="257"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="394"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="466"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="554"/>
            <end position="609"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="295"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="399"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="9">
        <location>
            <begin position="556"/>
            <end position="575"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="OBZ91673.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="609" mass="70126" checksum="A8E148B00C298BA3" modified="2016-11-30" version="1">MQPANKDNLMNFKVLSRYDDLFTDIFLDNLYLWFSTIKMNNDHRRPRVPNTKILDIIQKHVLEKARPTDAVNELLALDYFRHYIASKNQRQVQEFVQHMKRYLYMYMPNAGYEIGDTRRYGGHGRRVEACLVATKDWHVGDEMRLLTGMIACLDPKDDAELKKGNRDFSVMWSTRKNCSCLFLGPARFANHDCDSNCKFISMGQNLITVKVLKEIQSGEEITVYYGKHYFGDNNSECKCSTCENLGMGYFASLGTPVQTEQGSTRRSTRKRKSVLQEEQKRSKRTSPTKTHSADSLEDLIGEEPEEPKKPFQPQDLPPMPVSPTTATTAKLKVMSIDFLCNKEETRERRTSNCPMLDMLVEAAMDAEYLSSNPTKTVIVNPEIHRDATQRILLRQQPQSTPDASSTDSKADSAISLSPPSHPIRIKAEQDDRCWQREMDDALFNQDDMDVLSDFLDDVSDLSSVSSTELSNWTSDEEEEEHVSKKKKSQQDLSCIACMRPLRREDISEQLGADVSVTNELATWTWTPSAIFTDWKPKRCPRCERHYTIFRQEWPSRKPKKKSSKKPKKKKTKKKPITTLSQDERSLDDYIPPSPLSEISHFEDEEITTF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NS69</accession>
    <name>A0A1C7NS69_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_00142</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000003">
        <property type="protein sequence ID" value="OBZ91809.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NS69"/>
    <dbReference type="STRING" id="101091.A0A1C7NS69"/>
    <dbReference type="InParanoid" id="A0A1C7NS69"/>
    <dbReference type="OrthoDB" id="2017405at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021475">
        <property type="entry name" value="Pants/Emi1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28052">
        <property type="entry name" value="UPF0545 PROTEIN C22ORF39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28052:SF1">
        <property type="entry name" value="UPF0545 PROTEIN C22ORF39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11326">
        <property type="entry name" value="PANTS-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ91809.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="119" mass="13714" checksum="5D831EF56F6DD8C2" modified="2016-11-30" version="1">MYSFFNSELWKNPIAVGDLAGWVPFVDSMNKTATVRQRRQHSSQGKSVKCYTLSSQATNYYRYGTKKDCSGKWDDFKFCLKTKTKPVDVADAMLRERKAAKEAVKKQGRSSEEVWEARQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NV11</accession>
    <name>A0A1C7NV11_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Subtilisin inhibitor-like protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">SSI1_1</name>
        <name evidence="3" type="ORF">A0J61_00655</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000015">
        <property type="protein sequence ID" value="OBZ91314.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NV11"/>
    <dbReference type="InParanoid" id="A0A1C7NV11"/>
    <dbReference type="OrthoDB" id="2270081at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004867">
        <property type="term" value="F:serine-type endopeptidase inhibitor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.350.10">
        <property type="entry name" value="Subtilisin inhibitor-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023549">
        <property type="entry name" value="Subtilisin_inhibitor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036819">
        <property type="entry name" value="Subtilisin_inhibitor-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00720">
        <property type="entry name" value="SSI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55399">
        <property type="entry name" value="Subtilisin inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008889938" evidence="1">
        <location>
            <begin position="19"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="domain" description="Subtilisin inhibitor" evidence="2">
        <location>
            <begin position="30"/>
            <end position="104"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00720"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ91314.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="118" mass="12294" checksum="369F957217130CBB" modified="2016-11-30" version="1">MFKLTLCLLASLALFVSAAPGATSDRLTISCSSQKAKYTLSCSPVGGNHPHRQEACKALKRCGGNLNSIPPTTTICSSVFAPVTVTVEGTYGGKAVNLQREYENPCAANAHLGPIVQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7LKX4</accession>
    <name>A0A1C7LKX4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">PRELI/MSF1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_11933</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01002723">
        <property type="protein sequence ID" value="OBZ65373.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7LKX4"/>
    <dbReference type="STRING" id="101091.A0A1C7LKX4"/>
    <dbReference type="InParanoid" id="A0A1C7LKX4"/>
    <dbReference type="OrthoDB" id="407630at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006797">
        <property type="entry name" value="PRELI/MSF1_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04707">
        <property type="entry name" value="PRELI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50904">
        <property type="entry name" value="PRELI_MSF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PRELI/MSF1" evidence="1">
        <location>
            <begin position="1"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50904"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ65373.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="67" mass="7378" checksum="EBF0AF063B665801" modified="2016-11-30" version="1" fragment="single">PEDSSKTQFTQQAAISAGSLVSTWSNILEDFSLKRFQQNAAVGRAGFTKVLERFVVMAEAQQQTNNV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7LNQ9</accession>
    <name>A0A1C7LNQ9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_11931</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01002718">
        <property type="protein sequence ID" value="OBZ65639.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7LNQ9"/>
    <dbReference type="STRING" id="101091.A0A1C7LNQ9"/>
    <dbReference type="InParanoid" id="A0A1C7LNQ9"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="22"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="58"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="69"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ65639.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="69" mass="7845" checksum="518DDCA531696AFB" modified="2016-11-30" version="1" fragment="single">MDVDNEPVVKQQVQEEFEEIDTTNKPRVLKDTSLLDRGKGIKKQSRTNSPSPSIPPGSKTNMTRDQIKY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MNT4</accession>
    <name>A0A1C7MNT4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_11849</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01002585">
        <property type="protein sequence ID" value="OBZ78523.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MNT4"/>
    <dbReference type="InParanoid" id="A0A1C7MNT4"/>
    <dbReference type="OrthoDB" id="2225763at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ78523.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="240" mass="27657" checksum="AB093AFB53FBBE6B" modified="2016-11-30" version="1">MLFLSLVRQLCLKFASWQNKPITENTLIFQNIACFVDVFLLNDSSFFGVWTHGTLERYDVESSNLDEIKSSKSSSRKRTSSNSNSKKRLLPDLIVKCKVEDEICFDLLVMEVKNKDVKPSQAISDNAKIAMCLKKMLDEQVAFGVQDPVALGLEVEVEKVKIFIAKLQHESVYQVHLDSHFFLPRDYTDICSIPRVMQCLIKINKILKGLKKRLRSRNNSNSIPTSWRRPSFDWPVHESE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MTY6</accession>
    <name>A0A1C7MTY6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Transcription activator GCR1-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_11663</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01002313">
        <property type="protein sequence ID" value="OBZ80288.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="InParanoid" id="A0A1C7MTY6"/>
    <dbReference type="OrthoDB" id="4325529at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0060963">
        <property type="term" value="P:positive regulation of ribosomal protein gene transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052146">
        <property type="entry name" value="HOT1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022210">
        <property type="entry name" value="TF_GCR1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37784:SF2">
        <property type="entry name" value="HIGH-OSMOLARITY-INDUCED TRANSCRIPTION PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37784">
        <property type="entry name" value="PROTEIN MSN1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12550">
        <property type="entry name" value="GCR1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Transcription activator GCR1-like" evidence="1">
        <location>
            <begin position="139"/>
            <end position="184"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12550"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ80288.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="199" mass="22506" checksum="8C6CDE122CB37C19" modified="2016-11-30" version="1">MKLKEIVPEIEVVLNNMNMKLDSVSTIVNHINSQTXRSIINSSSTSNDNNLAAINVLMRNIATNFNQLKSACAYFVNGSPRVDSEAHVDDDEEQLAIGLSNGLTGESSSIPVASTANVELVKCSMKRWVKRVPGLWLEFTVSWRRYEKERKMYSRRITIINKIRQLVSEGMTEEDAVKQLEEKRVSEKLSLNKLHDALK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MUK8</accession>
    <name>A0A1C7MUK8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_11386</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001977">
        <property type="protein sequence ID" value="OBZ80565.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="InParanoid" id="A0A1C7MUK8"/>
    <dbReference type="OrthoDB" id="2447509at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ80565.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="105" mass="11782" checksum="5A93860A68531FD5" modified="2016-11-30" version="1">MTQIATEQRGNLDNDDXREGIASLENVKLVFRAEGVLDRRLYNRPTGGSQVAVITVSGDNDDNAVTNSRGIVVQYQESSVTRVSESNQFYDPLHYALLFPFVSFW</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MV35</accession>
    <name>A0A1C7MV35_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_11206</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001775">
        <property type="protein sequence ID" value="OBZ80745.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MV35"/>
    <dbReference type="InParanoid" id="A0A1C7MV35"/>
    <dbReference type="OrthoDB" id="2281860at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.443.20">
        <property type="entry name" value="Centromere DNA-binding protein complex CBF3 subunit, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038279">
        <property type="entry name" value="Ndc10_dom2_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ80745.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="61" mass="7219" checksum="A579591D17B42EE3" modified="2016-11-30" version="1">MQPMMLLRGESTRRMDLTDLFTLDLKDEDYSERPALVFLMREGKTNHTGRSEYATTIRHKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MVB4</accession>
    <name>A0A1C7MVB4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_11245</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001819">
        <property type="protein sequence ID" value="OBZ80707.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MVB4"/>
    <dbReference type="InParanoid" id="A0A1C7MVB4"/>
    <dbReference type="OrthoDB" id="2241374at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ80707.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="254" mass="29838" checksum="B11CC04B9CF30020" modified="2016-11-30" version="1">MECLDSIFDLVKHTSIQHLNVHVRHPYDHSFIENYTLGLLYAFSVLDSQSIPSLSIYFRYFDWTDYTLTESNYLIREIPEALDSSSTVYKATSHHTLSFEFGIGEEYDFNEMNVLSTWLTKPINFLVTHLTLERQIRDTNYAGKACPLFLDSVLAHFPQLISLTYSREIKLRKGIDNADLALLTLLDRHDNTKHEHIRYLHIKNVKIDRYVYRHLFRQCPHIVKIELVNCDLDEETVLALEYYCLSNDVTLILK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MVT4</accession>
    <name>A0A1C7MVT4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">60S ribosomal protein L3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">rpl-3</name>
        <name evidence="5" type="ORF">A0J61_11063</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the universal ribosomal protein uL3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001637">
        <property type="protein sequence ID" value="OBZ80887.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MVT4"/>
    <dbReference type="FunCoup" id="A0A1C7MVT4">
        <property type="interactions" value="312"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7MVT4"/>
    <dbReference type="InParanoid" id="A0A1C7MVT4"/>
    <dbReference type="OrthoDB" id="1611972at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022625">
        <property type="term" value="C:cytosolic large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.30.10:FF:000079">
        <property type="entry name" value="60S ribosomal protein L3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1430.10:FF:000001">
        <property type="entry name" value="60S ribosomal protein L3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="4.10.960.10:FF:000002">
        <property type="entry name" value="60S ribosomal protein L3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.30.10:FF:000351">
        <property type="entry name" value="Ribosomal protein L3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1430.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.960.10">
        <property type="entry name" value="Ribosomal protein L3, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.10">
        <property type="entry name" value="Translation factors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045077">
        <property type="entry name" value="L3_arc_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044892">
        <property type="entry name" value="Ribosomal_L3_dom_3_arc_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000597">
        <property type="entry name" value="Ribosomal_uL3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019926">
        <property type="entry name" value="Ribosomal_uL3_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11363">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11363:SF5">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN UL3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00297">
        <property type="entry name" value="Ribosomal_L3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="Translation proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00474">
        <property type="entry name" value="RIBOSOMAL_L3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 5" id="KW-0689">Ribosomal protein</keyword>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003905"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OBZ80887.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="351" mass="39839" checksum="47C365740E3A41EE" modified="2016-11-30" version="1" fragment="single">AKLPVHLTAFMGYKAGMTHIVRDLERPGSKMHKKEIVEAVTVIESPPMVIVGMVGYVETPRGLRSLTTVWAEHLSEEAKRRFYKNWYRSKKKAFTKYAQKYADGAKDITRETERIKKYCSVVRVLAHTQISKAKINQRKAHIMEIQLNGGSIADKVDFARNHFEKEVSVGSIFEQDEMIDIIATTKGHGFEGVTHRWGTKKLPRKTHRGLRKVACIGAWHPSRVMYSVARAGQRGYHRRTEINKKIYRIAKGSDAKSGTTEYDLTEKNITPMGGFPHYGVVNDDFVMIKGCCAGSKKRVITLRKSLTVHTKRSALEKVTLKFIDTSSKFGHGRFQTAAEKHQFMGTLKKDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MW61</accession>
    <name>A0A1C7MW61_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_10897</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001497">
        <property type="protein sequence ID" value="OBZ81053.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MW61"/>
    <dbReference type="InParanoid" id="A0A1C7MW61"/>
    <dbReference type="OrthoDB" id="2281596at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ81053.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="220" mass="24633" checksum="F6C0DACCA9D5941D" modified="2016-11-30" version="1">MLVSLVFEVNQHNVNKPEFHIQCGFIHPVVRSICKQNDNVVAHSSNKLAMDDQEASSSRVRPDYRVDMYDTTCSVVSTNMYGGVKPKNIKPVEVLNDFHKIAIFGKVGLKHSSTGAAMTFRSVDNHVFFYLNYRVANYGFVCLDLGDFEIPTTKGTLMSILGSLPLIYKLAYIYNCTCLNRAQVIPDQDNLSGYTTTLSFSLGKSIISNKDNKKRRSACL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MX79</accession>
    <name>A0A1C7MX79_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_10541</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001226">
        <property type="protein sequence ID" value="OBZ81410.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MX79"/>
    <dbReference type="STRING" id="101091.A0A1C7MX79"/>
    <dbReference type="InParanoid" id="A0A1C7MX79"/>
    <dbReference type="OrthoDB" id="2287076at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="64"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="79"/>
            <end position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ81410.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="390" mass="43128" checksum="93A984517EA07C4D" modified="2016-11-30" version="1">MANSSLDLQVSGNVLGPTLYRPLRRSNYQPPSKVRIVDGRSGIHLDRHLHDGLEPAFEPIYESTMESDRSLPSQDRPRSSSLRDNSSPPLDSGTLVSNPAPTKHRSSSSATTGLRAAQDPFDATSITQSELVALRMAAIRSGFNVFTKELMIKSLLADAATNRSYMPAQLLFFLWAHHLQIDVNNFHATDLINFLSNLHRSKKHQVATLLLARSAVTHFLFNPYSISSCGDISQYLNKLKLLAPPILLHRPTIELTPTFDALQSEDPATMIFAPLQRKLAFLLAFSERKTGSSSNHQFLLCQDAYKPSLVSYRCLSSSGTSSGKTTLFLLNSFCEHYLLSSPLATRTTGVWLKHYLRLSTSDVRVSVRSLASSLALRAGILKEDIVTMGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MXK4</accession>
    <name>A0A1C7MXK4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_10443</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001174">
        <property type="protein sequence ID" value="OBZ81508.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MXK4"/>
    <dbReference type="InParanoid" id="A0A1C7MXK4"/>
    <dbReference type="OrthoDB" id="2284791at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="322"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="439"/>
            <end position="507"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="333"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="452"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="463"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="481"/>
            <end position="494"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ81508.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="507" mass="58087" checksum="637DC6DAA3180051" modified="2016-11-30" version="1">MVINLLSELENYIAETQDPLLLDFVQKNENLVVMTNKFKSAINLKNKWVARFKNALIQLNKYDNRVFKVSSNVSADVWESMFNKACTKMEKKMTAEERTRFVQRAEKMMVEENKVTFFNAVNKLSLSLLKNFASLTAVEVETLKLSLSGLLNIASANFENVLKRHLSEDVFLTLQDARYNEDVDSETMKVIKETLTDLKKEAEKDEPDFKVKHGTNSFITLENQVRLVFQHYFTSLRLGAKRSVEFNFVALVNQLLCFVLNDTTLRTLPGETQCFATKKYILKNELSYSSSNKSSSSTAGRKIDILITTENEEEIAALEFKAEKGSRSKSQKSSKSNSQKSSSKRSALSLGQEGKSIRINKAILSSFPDQVTSNCGMDFNGWSGYSYAIIPFQDIHVIVKLKSFVLPSCQKDLQGDMLLDVLSAFYQIKQHWVTTAAAISRNSKGEEVKEEEKEEEEEEEEKEEQKEEQKEEQKEEQKEEKEEEDLEDDKEENDIVFFSPKLSPRTF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MYD2</accession>
    <name>A0A1C7MYD2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Reverse transcriptase zinc-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_11817</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01002533">
        <property type="protein sequence ID" value="OBZ80134.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MYD2"/>
    <dbReference type="InParanoid" id="A0A1C7MYD2"/>
    <dbReference type="OrthoDB" id="2278241at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ80134.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="153" mass="17807" checksum="99E76BF3EDCC3243" modified="2016-11-30" version="1">MILSNLLPETTSSSLPRISASQWQAFVDAPMQYNVRNVWYRLIHRQLSSRARLCPLMRDVEDDRCRVCHDIESDEHMLFTCPGKLSLSTLQLNLFNIRSPDRVSIYDILGAILQTIWRTHWDEVFNSVAFVEGSVLNATHKKILRFKAFLELK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MZ21</accession>
    <name>A0A1C7MZ21_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Sorting nexin-14</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">Snx14</name>
        <name evidence="4" type="ORF">A0J61_09929</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the sorting nexin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000974">
        <property type="protein sequence ID" value="OBZ82022.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MZ21"/>
    <dbReference type="STRING" id="101091.A0A1C7MZ21"/>
    <dbReference type="InParanoid" id="A0A1C7MZ21"/>
    <dbReference type="OrthoDB" id="5582218at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035091">
        <property type="term" value="F:phosphatidylinositol binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003114">
        <property type="entry name" value="Phox_assoc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013937">
        <property type="entry name" value="Sorting_nexin_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22775">
        <property type="entry name" value="SORTING NEXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22775:SF3">
        <property type="entry name" value="SORTING NEXIN-13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08628">
        <property type="entry name" value="Nexin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02194">
        <property type="entry name" value="PXA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00313">
        <property type="entry name" value="PXA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51207">
        <property type="entry name" value="PXA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PXA" evidence="3">
        <location>
            <begin position="39"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="240"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="242"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="276"/>
            <end position="294"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51207"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OBZ82022.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="552" mass="64836" checksum="E1CD4DE3BC256E34" modified="2016-11-30" version="1">MKKDTSLRPFHIRILFPDLLTLSKNDPRRFDTPKSITKSRAVDLELYTYFALLLRDFIHPWYKLLTTDEDLTREVRDILILIVQRLEKRLCEEVDWTELILVDLPNLLLIHYQDYRQAKKRLHMDHSSGCHSLTELFRGMQPHFALQPIENREKEYLGMLADSLLKILLRPQDYQSDCVRYLVRDILSNLVLFNAIDALTDPYTIHMIICKLLASYETTLDELEASGKFSETYYSASTNEQVKSKQQDHIISDHGSETPREEEKQLEGLTRQMQRLQEKRREKEGLDVMEDDLHPQTSPAEKPKGRKKFSFGYITLQVLLAPFRTLWLYLMATLTQSQERYQRVNQYKKRTRQIRLIEPSMDLIYNACRIEEKPVLQWTWQMIGMLFWPLIRVFGGALLVDKFLEQTVLHLLSEDHIVFYLRLGSDLLWPDGVFIQRTDPPTPLEKEQMRARAERLLTVSIPGIMNGTDKGCQFKLKLNMQIILLSSKISIEKVGTVMFNTKDLNELQNQIHDIVEPFQNKQINKHLIYLLVDHILAKVLPELLTSTNDPKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MZ42</accession>
    <name>A0A1C7MZ42_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Mitotic spindle assembly checkpoint protein MAD2B</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">Mad2l2</name>
        <name evidence="3" type="ORF">A0J61_09820</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the MAD2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000946">
        <property type="protein sequence ID" value="OBZ82130.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MZ42"/>
    <dbReference type="STRING" id="101091.A0A1C7MZ42"/>
    <dbReference type="InParanoid" id="A0A1C7MZ42"/>
    <dbReference type="OrthoDB" id="21254at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016035">
        <property type="term" value="C:zeta DNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.900.10">
        <property type="entry name" value="HORMA domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003511">
        <property type="entry name" value="HORMA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036570">
        <property type="entry name" value="HORMA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045091">
        <property type="entry name" value="Mad2-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11842">
        <property type="entry name" value="MITOTIC SPINDLE ASSEMBLY CHECKPOINT PROTEIN MAD2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11842:SF10">
        <property type="entry name" value="MITOTIC SPINDLE ASSEMBLY CHECKPOINT PROTEIN MAD2B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02301">
        <property type="entry name" value="HORMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56019">
        <property type="entry name" value="The spindle assembly checkpoint protein mad2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50815">
        <property type="entry name" value="HORMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HORMA" evidence="2">
        <location>
            <begin position="1"/>
            <end position="186"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010348"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50815"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ82130.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="210" mass="24388" checksum="91637494187F45A5" modified="2016-11-30" version="1">MSCLVETWLNQILYQCNIYPKAVFETQKKFEVPVQVVSHSDLKDYIANFVQSCYPLLQKDELKQVSLTVIAEENQAPIKKFVFSIHSLINSIDIPLDLLHESESVYSLADLKQHLRACLVRLHSVTIDDQESDMTFYLSMETKQSDNFPCKQQEDWIPAPNTDVTWGQIVPLKSLHMDIFRVSYVSWLMIYFNAFIMELSNSKKGKERCP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MZ89</accession>
    <name>A0A1C7MZ89_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Acyl-CoA-binding domain-containing protein 4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">ACBP4_1</name>
        <name evidence="4" type="ORF">A0J61_10222</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001077">
        <property type="protein sequence ID" value="OBZ81729.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MZ89"/>
    <dbReference type="STRING" id="101091.A0A1C7MZ89"/>
    <dbReference type="InParanoid" id="A0A1C7MZ89"/>
    <dbReference type="OrthoDB" id="432528at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.80">
        <property type="entry name" value="Kelch-type beta propeller"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015915">
        <property type="entry name" value="Kelch-typ_b-propeller"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006652">
        <property type="entry name" value="Kelch_1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46093:SF3">
        <property type="entry name" value="ACYL-COA-BINDING DOMAIN-CONTAINING PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46093">
        <property type="entry name" value="ACYL-COA-BINDING DOMAIN-CONTAINING PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24681">
        <property type="entry name" value="Kelch_KLHDC2_KLHL20_DRC7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00612">
        <property type="entry name" value="Kelch"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117281">
        <property type="entry name" value="Kelch motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0880">Kelch repeat</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="330"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="387"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="528"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OBZ81729.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="528" mass="58341" checksum="93B73242DDD9679B" modified="2016-11-30" version="1" fragment="single">MATAQRNSSLIMFGGETPLSTFNNSNMYELTQTSNSFDWRTINQVNAPPGNIYGQAVVSSDQNRMYLLGGMTNATDNREVPFQYYTFNFQNNSWTAAPTNTNATNMPLNRKLFSATYDNANKIYIYGGALNSTAIFNNFFSFDISTNQFTPLASPNVYRFGHTASYLSNGKIVVIGGSAQIVQNQTTLNTLVPMSTIHVYDIASNTWEEKTATAVGTMPSTRHVHNAVVTSDNKIIVFGGDNNEQIRNKAYLNQVAVLDTNTWQWSLPSIQGIPPSRRSYASGGLVGNNLVVAFGSGYNTYYNDINVLNLNTMSWLQSFDSSTGSGSSGLSGGAIAGISIACVVVLVIILFLLWKFQKYARWLVQRIHRDIWKPRTGEPLWAETTRIVCQIFLLFIFFIFLAFVIRQAINSPNVTQKIVKSVPEVQVPDVRFCFDGFPLYPSTDIRTPGVSCSTDTGYSCTQFVQPLNMSVFQPTFTDNLGAVSCVLFTAPKTFTLTSTSGSNNGSRLLFTMFGDQNAPQARVHVSVY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MZC9</accession>
    <name>A0A1C7MZC9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_09761</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000930">
        <property type="protein sequence ID" value="OBZ82187.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MZC9"/>
    <dbReference type="STRING" id="101091.A0A1C7MZC9"/>
    <dbReference type="InParanoid" id="A0A1C7MZC9"/>
    <dbReference type="OrthoDB" id="5592879at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="27"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="71"/>
            <end position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ82187.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="352" mass="40096" checksum="3123EA1DF2CBE6A5" modified="2016-11-30" version="1">MQSPRRRSILKGSHTPLRYNSPLFQHEQVKRRERLEEKKKVSFAPDTQLREDSPPIPNIIEETEPAGMSSDLFTSPLNSTRIRGSPLDQHRRDRQPDLFGSPPTNKSLHQRSGGHPPSLLNKVYHEEQPDLTHFLHPHQKSPHNLFEDGSSDEEERVEGSSSRKKQRLDEDVTMEITQVIGPLEKKKEQQEEEEDDAMQITQEIAYPMEFSPLRPIAYHSPIRPSPSPVAYSPLRPQSNMLVASPATAKSTQSRMSSAYSPAKSFYLHDRSPLSTHSRRSMSMGSDHVFSYDQTNLLEEEFSGLYDSTIEEGDLDPNITLTDFLRYVGIEFPNPTPKPFKPTFHEASSKLGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N020</accession>
    <name>A0A1C7N020_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">ATP synthase mitochondrial F1 complex assembly factor 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">Atpaf2</name>
        <name evidence="6" type="ORF">A0J61_09490</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ATP12 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000862">
        <property type="protein sequence ID" value="OBZ82460.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N020"/>
    <dbReference type="FunCoup" id="A0A1C7N020">
        <property type="interactions" value="409"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N020"/>
    <dbReference type="InParanoid" id="A0A1C7N020"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033615">
        <property type="term" value="P:mitochondrial proton-transporting ATP synthase complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3580.10">
        <property type="entry name" value="ATP12 ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2180.10">
        <property type="entry name" value="ATP12-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011419">
        <property type="entry name" value="ATP12_ATP_synth-F1-assembly"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042272">
        <property type="entry name" value="ATP12_ATP_synth-F1-assembly_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023335">
        <property type="entry name" value="ATP12_ortho_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21013:SF10">
        <property type="entry name" value="ATP SYNTHASE MITOCHONDRIAL F1 COMPLEX ASSEMBLY FACTOR 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21013">
        <property type="entry name" value="ATP SYNTHASE MITOCHONDRIAL F1 COMPLEX ASSEMBLY FACTOR 2/ATP12 PROTEIN, MITOCHONDRIAL PRECURSOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07542">
        <property type="entry name" value="ATP12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160909">
        <property type="entry name" value="ATP12-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0143">Chaperone</keyword>
    <keyword evidence="4" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0809">Transit peptide</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008231"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OBZ82460.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="286" mass="32625" checksum="B30A325F8BF6367F" modified="2016-11-30" version="1">MSSFKLLTRPAAQWARSHRSIHTSAILRNAVEKEEAATQRAERTMTRFWKRAGIKEDADSVTVVLDQRNLRTPSKHIVKFPKERRQLALMTAAEWDAQTKNLKAHTLPLTSIVARSFDAFDPTLAEDPTVRSAVIDKLFTYFDTDSICYFEELPEVLTNLQDKYWKPIIDWTEKTYQVKINTTNDIFAVTQPEETKAKLRSVVEQMDPLGLASFEKAVMSSKSFLIGFALVHHGITVEQAAQAAHVEMNAQMERWGEVEDSHDVEREYIRQTLGSVAIAMMDKHQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N090</accession>
    <name>A0A1C7N090_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_09479</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000860">
        <property type="protein sequence ID" value="OBZ82472.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N090"/>
    <dbReference type="InParanoid" id="A0A1C7N090"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ82472.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="82" mass="9190" checksum="820AD82F1E8F316C" modified="2016-11-30" version="1">MDQGCYRCTSCFDAFMSAEDVALHETKDPLCNTVRRRSTAFSIVDPNSTYTSPVGPSFARKPTLHAIPYHLLLILPQKKKSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N0L4</accession>
    <name>A0A1C7N0L4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_09338</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000828">
        <property type="protein sequence ID" value="OBZ82612.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N0L4"/>
    <dbReference type="FunCoup" id="A0A1C7N0L4">
        <property type="interactions" value="88"/>
    </dbReference>
    <dbReference type="InParanoid" id="A0A1C7N0L4"/>
    <dbReference type="OrthoDB" id="2256928at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="543"/>
            <end position="582"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="598"/>
            <end position="631"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="362"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="565"/>
            <end position="578"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="616"/>
            <end position="631"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="631"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ82612.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="631" mass="72696" checksum="B84159F277E6EAE4" modified="2016-11-30" version="1" fragment="single">MATHGQMYVAMSRVRRPEDLYFFGADLPLKIKRKFGADVDAVESPNKSRFNDYEISLHPTCPFPDKQQQTDEGYLNNTTNEHAENTLEDNLSEKKTSFSRRPSQLSQDLSFNALCPPSHVLKARRLSKNTIKASVSTPIISSTQRSRKPSFVDGYQKEFISSQSAVSPRFMALRKLSEVTSLPSHSLSFAAVPPVPQIPSSYQPSAENKEEDTLENRMLSRIDDIIETQLQFHLGQIVWRASENHLEARRFWEEQKKDMLSFAANVVDRMESQMDIQRKAISASERKHEDHSECRQSRLSDYPLFDFEVLKTRNTELERQHELDLVSLQTLAQTTEAMASRLKALEQPAPKTPEGSVDRKKLYDLETENKQLKSQIQQMQEINQQLLEEATAHENKIKTQNKELRQLKHQLAEAELTILNTKRRMKSTSSTSTVSLEDRGIDCSEDFGKKTKKKKRPSIEDWADMMQSEDEAKKTAEEWALKYKELQLKYHEVCTTLEENNPEDLTVLLNKKDEEIRHLKQAENVNRIQIDYLQLELDKYQKKSSTDVKQKARRSQPPRTRPITPVNQTVPTKPSNPDSGYITEDGYLTFTTEINGKPSRYSIKIPQKPREHVKNSKLNPNASAWKKQQSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N199</accession>
    <name>A0A1C7N199_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">TLC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_09080</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000769">
        <property type="protein sequence ID" value="OBZ82870.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N199"/>
    <dbReference type="STRING" id="101091.A0A1C7N199"/>
    <dbReference type="InParanoid" id="A0A1C7N199"/>
    <dbReference type="OrthoDB" id="341353at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="15"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="45"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="86"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="166"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="196"/>
            <end position="214"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ82870.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="257" mass="29797" checksum="BA27CC063461869C" modified="2016-11-30" version="1">MATKLTFSQAFSQPVIPISLLASTCTLLGFFFYMKSRFAKTEKQVSWILTLASSFVCTVVSIPYFVRFWLSGWDMASLQVESDYHSAVACFFISYLVLDLTLGSIYYVKQITILTGWIHHPLYIYILSWLIRCQSSSFFTTNCILELPTLVLALGSMQKRWRCDILFAVSFFVLRLVFHSYMIIALKQKHRLESLWVLAVVVFPLHIYWFYGIISSLMKKYPLTSFSLLSSSSKVNSTKIVHRRKPKNSFLERVYTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N1R3</accession>
    <name>A0A1C7N1R3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">E3 ubiquitin-protein ligase RBBP6</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">Rbbp6</name>
        <name evidence="4" type="ORF">A0J61_09314</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000822">
        <property type="protein sequence ID" value="OBZ82636.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N1R3"/>
    <dbReference type="STRING" id="101091.A0A1C7N1R3"/>
    <dbReference type="InParanoid" id="A0A1C7N1R3"/>
    <dbReference type="OrthoDB" id="106784at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004842">
        <property type="term" value="F:ubiquitin-protein transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016567">
        <property type="term" value="P:protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd16620">
        <property type="entry name" value="vRING-HC-C4C4_RBBP6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.60.10">
        <property type="entry name" value="Zinc finger, CCHC-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003613">
        <property type="entry name" value="Ubox_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001878">
        <property type="entry name" value="Znf_CCHC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036875">
        <property type="entry name" value="Znf_CCHC_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48134">
        <property type="entry name" value="GLYCOPROTEIN 96-92-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48134:SF2">
        <property type="entry name" value="OS04G0609100 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04564">
        <property type="entry name" value="U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00098">
        <property type="entry name" value="zf-CCHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00343">
        <property type="entry name" value="ZnF_C2HC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57756">
        <property type="entry name" value="Retrovirus zinc finger-like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50158">
        <property type="entry name" value="ZF_CCHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="CCHC-type" evidence="3">
        <location>
            <begin position="103"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="213"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="371"/>
            <end position="600"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="13"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="227"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="238"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="410"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="429"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="439"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="486"/>
            <end position="537"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="546"/>
            <end position="556"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="574"/>
            <end position="583"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OBZ82636.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="600" mass="70792" checksum="65059965CF07871F" modified="2016-11-30" version="1">MADEPNREEDKQQQQQDSSNNDPKQPSFRGNSGGFDPSLMKMGMMNPVQYQHFQQIMMMQQFRRQQIQRQAAAAAAAAMANGPNAPVSNIPPETQKPPTGYVCFKCGQPGHWIYYCPNVPKGQFVQRNTTHPTPRHETTPSRPQELTCIICEKLMTEAVLIPCCGKSYCITSTLDKTNTCPYCNQQTSTVDQLVPNKTLRLVIEDHLQQVEEEEKKKQEQIEEQEQEEQKKKEKEDVEMAETEEENTQETGNKGGGMPIQVFDSSQEERKMPTRKHYDNSMMMPNPDMFNNEMNWMNMARPPFMNNRFTGFGMPDMNWMKEGGEEGSERPPFMPFPGFNNEMAPFPGMPPHPNPQDMFGFNMFHHRGGFNGNSMRGARGRGGRGGYYHNSRRPPQQHDEETMATGSQEPTRSEKSDDHHSHHHYESKYTRHHRSKSPRRTRDESTSRHHKHRDDSREDSRHRRRDDDRYKHESSSSRHKSSSGYESRSRRDDSRSRRDDSRSRREDSRSKRDESRSKRDDSRSKRDDSRSRRDDKYSSRRYHHHDEDEEEEEEDEDRDYKRRRRSKSPHDRRSSSSRHRSRYSRSRDERRDRDRKRHDKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-06-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N1X7</accession>
    <name>A0A1C7N1X7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_08836</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000719">
        <property type="protein sequence ID" value="OBZ83112.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N1X7"/>
    <dbReference type="InParanoid" id="A0A1C7N1X7"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ83112.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="69" mass="8189" checksum="9CED844DF6AA38B7" modified="2016-11-30" version="1">MRNRVCIDVVTTRRRNVDEQSQIVSRSVVYFVFEKDEMLHQRIVSSFAFAVRLCEVEEDMETDKYALSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N2N2</accession>
    <name>A0A1C7N2N2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_10340</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001124">
        <property type="protein sequence ID" value="OBZ81614.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N2N2"/>
    <dbReference type="InParanoid" id="A0A1C7N2N2"/>
    <dbReference type="OrthoDB" id="2288352at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ81614.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="247" mass="28000" checksum="EE1B4C9A5F6433C9" modified="2016-11-30" version="1">MHKFLMQVHSEEIVAALTPSLSTSFANEIHRRLFGSSSQDKNTDNEEYLAACTSFNADDYVALLGKQGMSVGNERLPPSTLMSQKYDETFIDERMCFGLTASTSVSPSILIFKEINLMGNKYKSAASSTVNKRGSFALVRCSVGGRSMFRCCQIQFFFRHEVDVYDDFDDKFINMHTFAYVKWFKTSNIAFDKFQEHNFMQVVQNTFEPESVDSILPITNLFAPAAVVTNHLQNIDVVVHLPQRLIP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N307</accession>
    <name>A0A1C7N307_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Nucleoside diphosphate kinase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">A0J61_08916</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 7 8">Belongs to the NDK family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000735">
        <property type="protein sequence ID" value="OBZ83036.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N307"/>
    <dbReference type="STRING" id="101091.A0A1C7N307"/>
    <dbReference type="InParanoid" id="A0A1C7N307"/>
    <dbReference type="OrthoDB" id="2162449at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004550">
        <property type="term" value="F:nucleoside diphosphate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006241">
        <property type="term" value="P:CTP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006183">
        <property type="term" value="P:GTP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006228">
        <property type="term" value="P:UTP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.141">
        <property type="entry name" value="Nucleoside diphosphate kinase-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034907">
        <property type="entry name" value="NDK-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036850">
        <property type="entry name" value="NDK-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001564">
        <property type="entry name" value="Nucleoside_diP_kinase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46161">
        <property type="entry name" value="NUCLEOSIDE DIPHOSPHATE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46161:SF3">
        <property type="entry name" value="NUCLEOSIDE DIPHOSPHATE KINASE DDB_G0292928-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00334">
        <property type="entry name" value="NDK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01243">
        <property type="entry name" value="NUCDPKINASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00562">
        <property type="entry name" value="NDK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54919">
        <property type="entry name" value="Nucleoside diphosphate kinase, NDK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51374">
        <property type="entry name" value="NDPK_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 10" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Nucleoside diphosphate kinase-like" evidence="9">
        <location>
            <begin position="5"/>
            <end position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008142"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00017632"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00706"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU004011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00562"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OBZ83036.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="208" mass="24014" checksum="286C9BDF3045E963" modified="2016-11-30" version="1">METTKESTLAIITLNENTKETKDYILSQGFLIAQSKDIQFSPNEAHLFYQAHKEQSYYDKFIKWLTTFTLHAMILEKPNGIQEWKQLMGPSNYKKARKIQPDSIRALFGQNKADNITHGSDTVDHAKREIEFIFGPSRKRFISQIPIRTQQNMMLIEKCPLRFKGHSRIARPIGSFKIEPLKESSIKKSSLPIMKGRTLIQLSTKISV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N3E8</accession>
    <name>A0A1C7N3E8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">glutathione-specific gamma-glutamylcyclotransferase</fullName>
            <ecNumber evidence="1">4.3.2.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">chac2</name>
        <name evidence="3" type="ORF">A0J61_08304</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.3.2.7" evidence="1"/>
    <dbReference type="EMBL" id="LUGH01000627">
        <property type="protein sequence ID" value="OBZ83643.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N3E8"/>
    <dbReference type="FunCoup" id="A0A1C7N3E8">
        <property type="interactions" value="381"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N3E8"/>
    <dbReference type="InParanoid" id="A0A1C7N3E8"/>
    <dbReference type="OrthoDB" id="1933483at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003839">
        <property type="term" value="F:gamma-glutamylcyclotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061928">
        <property type="term" value="F:glutathione specific gamma-glutamylcyclotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006751">
        <property type="term" value="P:glutathione catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd06661">
        <property type="entry name" value="GGCT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.490.10">
        <property type="entry name" value="Gamma-glutamyl cyclotransferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006840">
        <property type="entry name" value="ChaC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013024">
        <property type="entry name" value="GGCT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036568">
        <property type="entry name" value="GGCT-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12192">
        <property type="entry name" value="CATION TRANSPORT PROTEIN CHAC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12192:SF2">
        <property type="entry name" value="GLUTATHIONE-SPECIFIC GAMMA-GLUTAMYLCYCLOTRANSFERASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04752">
        <property type="entry name" value="ChaC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110857">
        <property type="entry name" value="Gamma-glutamyl cyclotransferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0456">Lyase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012344"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ83643.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="223" mass="25557" checksum="0664280E4EDB9FF9" modified="2016-11-30" version="1">MPPTIETAEDIKNIQEQNNNNAQLQDGIWVFGYGSLIWKPPIHYEAKQIGYIKNYVRRFWQHSEDHRGTPEKPGRVVTLIPFDEWKEIESIEGHDRVTWGVAFKIPSDDVEATRAYLDHREKNGYTVHTVDVYSPEDDQVPAVRNALVYIGTTDNEAYVGPAPYDAIAQQIYETYGPSGWNAEYLLNLAEALREISPGVRDDHVFELEARVRKLIDASQQKTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N3L1</accession>
    <name>A0A1C7N3L1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Protein Jade-1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">jade1</name>
        <name evidence="7" type="ORF">A0J61_08290</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000624">
        <property type="protein sequence ID" value="OBZ83660.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N3L1"/>
    <dbReference type="STRING" id="101091.A0A1C7N3L1"/>
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    <dbReference type="OrthoDB" id="20839at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd15571">
        <property type="entry name" value="ePHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd15492">
        <property type="entry name" value="PHD_BRPF_JADE_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050701">
        <property type="entry name" value="Histone_Mod_Regulator"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001965">
        <property type="entry name" value="Znf_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019787">
        <property type="entry name" value="Znf_PHD-finger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13793:SF107">
        <property type="entry name" value="BROMODOMAIN-CONTAINING PROTEIN HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13793">
        <property type="entry name" value="PHD FINGER PROTEINS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13832">
        <property type="entry name" value="zf-HC5HC2H_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00249">
        <property type="entry name" value="PHD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50016">
        <property type="entry name" value="ZF_PHD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="PHD-type" evidence="6">
        <location>
            <begin position="5"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="170"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="268"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="407"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="170"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="191"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="232"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="272"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="293"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="318"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="336"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="378"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="407"/>
            <end position="430"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OBZ83660.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="517" mass="59124" checksum="6CF44C40DE77C52A" modified="2016-11-30" version="1">MPYEGDACVVCKGIKSTHENPIIYCDGEDKSNTENEKCNMPVHKRCYNLKEIPEGDWFCQSCLNKIKKKPTNIICCTTKDGALKPTDMPGKYMHIVCGMWNKSVVSKKEPYTIVESELGQHKCMYCSKKQGLCIACEDNSCSVHFHVTCAINKGMLKAFAVVPDEYSPRCSRHQIKSQKKGRRLRAKHIDDTEESEEETEEDSEESDEDADEEESDRDSDDDEEEEEEDEEEKMKKEMEEKKKNPMFMAPKKKLALSSNKLIAQNAANMKSLKKDIPAKRHTRFDESSDDDMGTSNNKKPRNMSNPANYRKNPALGISLNNNNPPSNTQQKNDGMSYRERFKKPDTELIPSLLSELKRPSTGNAVASPSAMDDHFRRQQIQQQQAQHTQQLQQQQQQQQQQQQQQQLVQPQPQSQPQLAQLLQQQQSPQQANKNTSIELNKLREEVKKLNSFKQKVAEIFLALNVPVSPSTPSPQIDVESYVDHLRQTIQRVGPVRDDEMDQIKDYAESLVSKSKPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N3V0</accession>
    <name>A0A1C7N3V0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Calcium/calmodulin-dependent protein kinase type I</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">cmk1</name>
        <name evidence="4" type="ORF">A0J61_08122</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000598">
        <property type="protein sequence ID" value="OBZ83825.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N3V0"/>
    <dbReference type="FunCoup" id="A0A1C7N3V0">
        <property type="interactions" value="277"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N3V0"/>
    <dbReference type="InParanoid" id="A0A1C7N3V0"/>
    <dbReference type="OrthoDB" id="40902at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004683">
        <property type="term" value="F:calcium/calmodulin-dependent protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005516">
        <property type="term" value="F:calmodulin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071277">
        <property type="term" value="P:cellular response to calcium ion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106057">
        <property type="term" value="P:negative regulation of calcineurin-mediated signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010972">
        <property type="term" value="P:negative regulation of G2/M transition of mitotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000122">
        <property type="term" value="P:negative regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd05117">
        <property type="entry name" value="STKc_CAMK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000571">
        <property type="entry name" value="Maternal embryonic leucine zipper kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24347">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="3">
        <location>
            <begin position="12"/>
            <end position="302"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OBZ83825.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="378" mass="42833" checksum="DA3E7B83BE43BBD6" modified="2016-11-30" version="1">MSRQPVTVPCKYKTGRVLGNGTYATVKGKRADETEKEMSYACELLKDTIKLNRLMTCLKQIETGKYYACKIINKKLMEGREHMIRNEINILKRVSQGNKNILSLVDYFETLNNLYLVTDLASGGELFDRICEKGSYFEKDAAHIVQTICAAVAYLHENGIVHRGMYIPENLLFRERDEDADLLIADFGLSRIIDTEKFHTLKTTCGTPGYMAPEIFKKTGHSKPVDMWAIGVITYFLLSGYTPFERDNNIEEMNAIMHADYNYDDACWDNISDTAKNFIDRCLTIDANERITAHQALEHPWLLDAANQSKSQTDGGDLLPNLRTNFNARRTFKKAINMVTLSNHFGHSLLKNNSTNTTSVADEIKPVNEGIDQVLESS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N428</accession>
    <name>A0A1C7N428_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="11">General transcriptional corepressor ssn6</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">ssn6_0</name>
        <name evidence="11" type="ORF">A0J61_08086</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the CYC8/SSN6 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000592">
        <property type="protein sequence ID" value="OBZ83863.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N428"/>
    <dbReference type="InParanoid" id="A0A1C7N428"/>
    <dbReference type="OrthoDB" id="418911at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017053">
        <property type="term" value="C:transcription repressor complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031490">
        <property type="term" value="F:chromatin DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010468">
        <property type="term" value="P:regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.10:FF:000403">
        <property type="entry name" value="General transcriptional repressor, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.10:FF:000078">
        <property type="entry name" value="Transcriptional corepressor Cyc8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051630">
        <property type="entry name" value="Corepressor-Demethylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14017:SF1">
        <property type="entry name" value="LD02225P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14017">
        <property type="entry name" value="LYSINE-SPECIFIC DEMETHYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00515">
        <property type="entry name" value="TPR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13174">
        <property type="entry name" value="TPR_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13181">
        <property type="entry name" value="TPR_8"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="9"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81901">
        <property type="entry name" value="HCP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50293">
        <property type="entry name" value="TPR_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0678">Repressor</keyword>
    <keyword evidence="4 9" id="KW-0802">TPR repeat</keyword>
    <keyword evidence="6" id="KW-0804">Transcription</keyword>
    <keyword evidence="5" id="KW-0805">Transcription regulation</keyword>
    <feature type="repeat" description="TPR" evidence="9">
        <location>
            <begin position="34"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="9">
        <location>
            <begin position="101"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="9">
        <location>
            <begin position="137"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="9">
        <location>
            <begin position="174"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="9">
        <location>
            <begin position="211"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="9">
        <location>
            <begin position="283"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="9">
        <location>
            <begin position="317"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="399"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="471"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00061082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="OBZ83863.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="519" mass="59221" checksum="00D97BEE43DDC812" modified="2016-11-30" version="1">MSSTLSRNMNYSQPPPPPPPPIVDTAKKLSSVNEQTWLRFGSLAEMMNDQDKAIEAYQSAXRHNPQSIPALTQMAGLFRAKEKFSEAHYFKMILALQENNGEAWASLGHCYLMIDGLQEAYDAYQQALHHLQNPKDPKLWYGIGILYDRYGSLEHAEEAFSAVMRMDPQFEKSNEIYFRLGIIYKQQRKFDPSLQCFRHILHNPPAPLTESDIWFQIGHVHEQKKEYDAAKEAYEHVLSEHPNHAKVLQQLGWLYHQPETSFCNQQLATDFLTQSLKTDGNDAQSWYLLGRCYMANQNHNKAYEAYQQAVYRDARNPIFWCSIGVLYYQISQYRDALDAYSRAIRLNPYISEVWYDLGTLYESCNNQVQDALDAYHRAAELDPHNALIKQRLEHLERNQNSSNGSAGEAPAPRDISDPGQYASNAMAGSSSLLPYDQRSKQAMDHPRSKPETDRDLTLNALSSMASPVTTLNGLKSAIKEEPKSPQPTVAFKHPNDDHDMAEAARIPKQEDQISMDTSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N4D3</accession>
    <name>A0A1C7N4D3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Ran-specific GTPase-activating protein 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">YRB2</name>
        <name evidence="5" type="ORF">A0J61_08039</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000585">
        <property type="protein sequence ID" value="OBZ83911.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N4D3"/>
    <dbReference type="FunCoup" id="A0A1C7N4D3">
        <property type="interactions" value="7"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N4D3"/>
    <dbReference type="InParanoid" id="A0A1C7N4D3"/>
    <dbReference type="OrthoDB" id="185618at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="CDD" id="cd13180">
        <property type="entry name" value="RanBD_RanBP3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000156">
        <property type="entry name" value="Ran_bind_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045255">
        <property type="entry name" value="RanBP1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23138">
        <property type="entry name" value="RAN BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23138:SF142">
        <property type="entry name" value="RAN-BINDING PROTEIN 3B-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00638">
        <property type="entry name" value="Ran_BP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00160">
        <property type="entry name" value="RanBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50196">
        <property type="entry name" value="RANBD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RanBD1" evidence="4">
        <location>
            <begin position="264"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="218"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="70"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="87"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="111"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="125"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="218"/>
            <end position="245"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50196"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OBZ83911.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="406" mass="44059" checksum="C1B7971B29B31A7F" modified="2016-11-30" version="1">MSSPTDSITDLDEASLNKKRGRATSVEPTADQHAPIQDKSTTEAITSIAPKKTKREDEDSTATVGSIRRNMKDMSTTDRVSEEAEESSSSPEQPSLLAQFGGSKSGHADDDWGEFADEDEDEDDVNQKTTKEPVAEEKPKYTFGASSGFGTKGWAATHQTIPKSTFGSFGDFKSSPMASNTNLTVSTEHKQVPSFSSFAKATSSPFAAAAAAAVSNTKGNDTPINAFSGNSTETNSSASSPNTVGLSKERQEESDTSFGGSVKVKVPGVKQTEVKTGEEEEDTIFQTKAKLLVLDTATSNWKERGVGTFRINQNEETNQARLVMRTDSVYRLILNLKLFKGMKVFIMQDKFVRFAGFEAEVKEDNTSETKLINFALKLGSPSVAQDVCERIIKCIPSDEEEEKEAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N4E5</accession>
    <name>A0A1C7N4E5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_08451</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000651">
        <property type="protein sequence ID" value="OBZ83499.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N4E5"/>
    <dbReference type="InParanoid" id="A0A1C7N4E5"/>
    <dbReference type="OrthoDB" id="2275636at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ83499.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="106" mass="11998" checksum="3263B0E884F847B0" modified="2016-11-30" version="1">MVQNLRNRSIVDKVFVSKSSNANQPFDKRDINSTIIEGTDGTTKEIILVVLDYAGLTTNVEDRKEFLIDKLPITTNVEVYQTDLLLQGQKAINESDCRTRPVQRSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-06-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N4N3</accession>
    <name>A0A1C7N4N3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_08329</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000630">
        <property type="protein sequence ID" value="OBZ83626.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N4N3"/>
    <dbReference type="InParanoid" id="A0A1C7N4N3"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="494"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ83626.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="494" mass="56195" checksum="4BA2405015C32169" modified="2016-11-30" version="1" fragment="single">MSFVEGPEDIVLQSIKGGDLIGDIDRTLTGFMQCDISSEFCATLLVPFLKHAAENNQLTQDILVYSRIFQDIYIYVLKDDPSNDQLLIEAQQSLLELQSFLTHESITEITYLSSLRGLAPIKILTIMDSILNFISPLLSKNIIRFSEPIVSVVWDAIPIIIMHLVKLRYPKDTLLKALVDSIKNSLEGLKHTYPSRWTVTSLLQSLLVLWDQGGLDEKSKDEVADVISAVVVSAPEADQGDFLELDALTVPITIKEASTCNGVQAHALFCIFCFLVKNHVKPQIIEWPDERSLHSLSHVREKVALFFESNQKEMSSQYMEVDLNSMPTRNVTRSQLGCFQQALQDQLEKITRMMVNMREHKFDISREDLDQLMDSMKEAVIISGNTDWEDLFYNQMEHVVPLIIYLLTADEAEADSITHLFGHDVNGFLIYYMHFALYYALISDEEGALLRMATTIDMTVENMCIEHGHHLVIALMKEEDQAVKKFAIRRLNNV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N4Z0</accession>
    <name>A0A1C7N4Z0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Protection of telomeres protein 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">pot1</name>
        <name evidence="10" type="ORF">A0J61_08242</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Chromosome</location>
            <location evidence="2">Telomere</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the telombin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000617">
        <property type="protein sequence ID" value="OBZ83709.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N4Z0"/>
    <dbReference type="FunCoup" id="A0A1C7N4Z0">
        <property type="interactions" value="160"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N4Z0"/>
    <dbReference type="InParanoid" id="A0A1C7N4Z0"/>
    <dbReference type="OrthoDB" id="2186770at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000783">
        <property type="term" value="C:nuclear telomere cap complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098505">
        <property type="term" value="F:G-rich strand telomeric DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010521">
        <property type="term" value="F:telomerase inhibitor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032210">
        <property type="term" value="P:regulation of telomere maintenance via telomerase"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016233">
        <property type="term" value="P:telomere capping"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028389">
        <property type="entry name" value="POT1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032042">
        <property type="entry name" value="POT1PC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011564">
        <property type="entry name" value="Telomer_end-bd_POT1/Cdc13"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14513">
        <property type="entry name" value="PROTECTION OF TELOMERES 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14513:SF0">
        <property type="entry name" value="PROTECTION OF TELOMERES PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02765">
        <property type="entry name" value="POT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16686">
        <property type="entry name" value="POT1PC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00976">
        <property type="entry name" value="Telo_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0158">Chromosome</keyword>
    <keyword evidence="7" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0779">Telomere</keyword>
    <feature type="domain" description="Telomeric single stranded DNA binding POT1/Cdc13" evidence="9">
        <location>
            <begin position="15"/>
            <end position="146"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008442"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00015253"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022895"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00976"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OBZ83709.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="485" mass="55393" checksum="1021C512DB0837A3" modified="2016-11-30" version="1">MMKTPYEITLAKSQYIALRDLKVGRFASVFGVIVHVSPIKVPQQSGKNYSCSLKITDPTLNSSSITINIFRPDGSLLPTANIGDIIFTRNVKVKMFNNSPQLTNEREMFYVCVDPYTRKAKMAQDRMVHFTRSDAEIIALLHQWSLNNISQVQAARVVSIGRPILTTQGIYEDSSRYFDYIGMVVGCYPEEGPAHKTNLVLTDFTDNPMPFMDDKGDYRLDIEYTKLLQCTLWDENSVRCPKLESGDYVLLRNCSRNEKNRNALEISMHGDRTGSTQSRNRVEILKPSDSRLKELLERKSRYVSTRHNSAKDVASLIGWGDDPLRTRVKDLKGHKSLKDIKESQQPGLYLTRAIIRKMSPNNVEDWIVGQCKHCRKFYKEPISLCDTCEGLNVPVFKVVFGIFDGTDEVPLVVFDKEAEMLFSGLSAEDAYIDESGMEQLRKLAKLIRHDNKDIYYDIGLYCYDTPGFGQTFRITRTEFIENNQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N608</accession>
    <name>A0A1C7N608_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Enhancer of polycomb-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">EPL1</name>
        <name evidence="10" type="ORF">A0J61_07370</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histone H4 and H2A. The NuA4 complex is also involved in DNA repair. Involved in gene silencing by neighboring heterochromatin, blockage of the silencing spreading along the chromosome, and required for cell cycle progression through G2/M.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the enhancer of polycomb family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000493">
        <property type="protein sequence ID" value="OBZ84585.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N608"/>
    <dbReference type="FunCoup" id="A0A1C7N608">
        <property type="interactions" value="405"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N608"/>
    <dbReference type="InParanoid" id="A0A1C7N608"/>
    <dbReference type="OrthoDB" id="435275at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035267">
        <property type="term" value="C:NuA4 histone acetyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024943">
        <property type="entry name" value="Enhancer_polycomb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019542">
        <property type="entry name" value="Enhancer_polycomb-like_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14898">
        <property type="entry name" value="ENHANCER OF POLYCOMB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10513">
        <property type="entry name" value="EPL1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0804">Transcription</keyword>
    <keyword evidence="3 7" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Enhancer of polycomb-like N-terminal" evidence="9">
        <location>
            <begin position="10"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="572"/>
            <end position="593"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="630"/>
            <end position="658"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="632"/>
            <end position="651"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00025513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU361124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF10513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OBZ84585.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="658" mass="73605" checksum="2C349FEF95C3D0AE" modified="2016-11-30" version="1">MPVQMVSRFRVKKLSPKHPLPIYKESQLPDLADTVNQIQRSVPQIETGVEKEEEEEHDLQAAISAHQAAVTTGAKVESYIPIPDASNRIDTKDYESLYKKKYKEPSTLIRFSSTVEDTIGCPYFMDEVDESFLNKFNAEHPTLSEDDFERIMYEFESVTKEKLPHIHLDPDHIPDYTNFMELAPESSFLHSRAPVMIEPIFAHWRKRKQDRKGHSIIPDLKYEELMKNEVDPYVCFRRRETKPVRKTRRTDQQSLERLRKLRSEMEMARNLLEMVLRREKIRKEGMVLDHTAFDKKCKLREYQRILGIKEDEDLLLPSKKKRKTSIGSGATIKIRLKKDDGRIEKSPAQLAIEADLARKKQLDAPYEDLTNCSYQPFPASLPSQFFETASNGIRYRKRVGRGGRIFIDRAGYQRPISHGGKTKPGVKLEESVTKRYQFDFDSNDEDSDIEVDEMQDSYLRHRTQLLSEMELRSLVTIPFLTPMNMINIQAARNQAAAAAAVAAAASTNGNNGIASGPSAASAIAASSQRLSLATGGNAAALAAAAAAAAANSNGNNNNGIANGLNLADGNRSASPGIAGHPLKRQASRSRMTPQQAAVAMANGMIAANMAAAVNGASNPNRTAVQMALAAAQQQQQQQQQQQQQQQQQQQQRNTNGIM</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N684</accession>
    <name>A0A1C7N684_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">tRNA ligase 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">trl1</name>
        <name evidence="2" type="ORF">A0J61_07270</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000482">
        <property type="protein sequence ID" value="OBZ84675.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N684"/>
    <dbReference type="STRING" id="101091.A0A1C7N684"/>
    <dbReference type="InParanoid" id="A0A1C7N684"/>
    <dbReference type="OrthoDB" id="276239at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003972">
        <property type="term" value="F:RNA ligase (ATP) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006388">
        <property type="term" value="P:tRNA splicing, via endonucleolytic cleavage and ligation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019039">
        <property type="entry name" value="T4-Rnl1-like_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32004">
        <property type="entry name" value="TRNA LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32004:SF1">
        <property type="entry name" value="TRNA LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09511">
        <property type="entry name" value="RNA_lig_T4_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0436">Ligase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="T4 RNA ligase 1-like N-terminal" evidence="1">
        <location>
            <begin position="68"/>
            <end position="286"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF09511"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ84675.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="367" mass="43238" checksum="0DC96A49693BA504" modified="2016-11-30" version="1">MSAVNIPSLDLDQAHTKDVIERLYKYKQEYPKELRSKEYTLEDGQVWTSWTMRESVYKKKTSVFPTMARGFFTQEEKRVMARGYDKFFNVFETSMTQWPALASDTEGPYEVTAKENGCIIFISVLSDEKVVVTSKHSIPSVKDDPKAHAGVGYRWLLTHLASVEKSEKDLAQWLSKQDITLVAELCDDEFEEHVLAYVEKDRGLYLHGANYNRVDLHTIPSGTVRQLAEDFGFHKTDYMVLETIEEVKQFSEDMQKTGLFRNREVEGAVVRCKRKGHDFMFKIKNERYLTFREYREVTNQLIETQEGLIRFVDKPNLKITYEKTRFYVDWLRKQVIANPDWFQQYKLQKGIIQVRLAFEDYWEKGQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N6F2</accession>
    <name>A0A1C7N6F2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">CCHC-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_07318</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000487">
        <property type="protein sequence ID" value="OBZ84627.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N6F2"/>
    <dbReference type="InParanoid" id="A0A1C7N6F2"/>
    <dbReference type="OrthoDB" id="2283392at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.60.10">
        <property type="entry name" value="Zinc finger, CCHC-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036875">
        <property type="entry name" value="Znf_CCHC_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57756">
        <property type="entry name" value="Retrovirus zinc finger-like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="51"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="57"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ84627.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="190" mass="21427" checksum="7E717E5AB5BECF0F" modified="2016-11-30" version="1">MPTWCCYCHQPNHTKFECEKSKASIICYSCQHFGHQSFECSRKVALPAQKKRKGSSLRRETAEKDYRPSKEVLKSQHAPGASTALKIQHSTNYFDSLPSLDESNSMRGQSYLTEIPEDNEDTKDPDYTMHYATSESDFSKFEDGIVDEESLDFIQDLHILTDAISETQSSFTIALPTPSPSLSLTTLTPT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N6M7</accession>
    <name>A0A1C7N6M7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_07165</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000469">
        <property type="protein sequence ID" value="OBZ84782.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N6M7"/>
    <dbReference type="InParanoid" id="A0A1C7N6M7"/>
    <dbReference type="OrthoDB" id="66510at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="271"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="12"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ84782.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="469" mass="53483" checksum="A0C7B8283EA9678E" modified="2016-11-30" version="1">MATLEKKRKSTSRPIQEDTQPTTTVSSVQDDQDLLDDLAKEPVEYNNLSCLSPQVVESLKSVKHTCLVVLDALLKQIIKELPSTQNHNRTRRLSESSCNLLSSLTQHTNVLQELSNDTSMSRSQSTPPPAIISDLYRLLDSNSAQHSTQHYTLSCSLAALLNDIYRLLELNSTQQHQDALLASRSDDITFLQQELHDKVSTFRHERAQGIMSIVEQDASQEMIMLWDEMDHLMNIVTKLAIHQLAPPAYDESDNKIDIPTKEKLPTYDSVLETNQNDLDQLLDAIDRLSHTVPRLNDQRVCLTDTQVKELAAAALSKSIERLSRGRMENQCASLPAKTRQEVLHDLVLQIQKSASRSLDNQRVVLNTQKQRNIELASIHGLVSRLEKTRYSDQDWISHEEMLIKDLSRTTDLLVKSLNRPAYNRQRYSLPATKERNMFMSSLFDKVQHLEKQRFVNQDAEFTSSSTRTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N7G3</accession>
    <name>A0A1C7N7G3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">RNA helicase</fullName>
            <ecNumber evidence="1">3.6.4.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="primary">dbp9</name>
        <name evidence="15" type="ORF">A0J61_06872</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.13"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the DEAD box helicase family. DDX56/DBP9 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.13" evidence="1"/>
    <dbReference type="EMBL" id="LUGH01000436">
        <property type="protein sequence ID" value="OBZ85075.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N7G3"/>
    <dbReference type="FunCoup" id="A0A1C7N7G3">
        <property type="interactions" value="616"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N7G3"/>
    <dbReference type="InParanoid" id="A0A1C7N7G3"/>
    <dbReference type="OrthoDB" id="1191041at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd17961">
        <property type="entry name" value="DEADc_DDX56"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18787">
        <property type="entry name" value="SF2_C_DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050079">
        <property type="entry name" value="DEAD_box_RNA_helicase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014014">
        <property type="entry name" value="RNA_helicase_DEAD_Q_motif"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47959">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE RHLE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47959:SF21">
        <property type="entry name" value="DEAD-BOX HELICASE 56"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51195">
        <property type="entry name" value="Q_MOTIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4 15" id="KW-0347">Helicase</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="DEAD-box RNA helicase Q" evidence="14">
        <location>
            <begin position="11"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="12">
        <location>
            <begin position="42"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="13">
        <location>
            <begin position="232"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="321"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="553"/>
            <end position="586"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="10">
        <location>
            <begin position="482"/>
            <end position="509"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Q motif" evidence="9">
        <location>
            <begin position="11"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="326"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="11">
        <location>
            <begin position="561"/>
            <end position="586"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="15">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00038041"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00047984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="OBZ85075.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="586" mass="66557" checksum="724CB57A3C2A5883" modified="2016-11-30" version="1" fragment="single">KYSLSRLMTEQTFASFDFDPRLARAIAQLNFTRPTPIQAQGIPLALAGKDILARARTGSGKTATYALPIVQKILTAKQDLETESVTKALILVPTRELAEQVTNHINKLLVYANQLVKVVNLAGQMSVQLQRPLLAEKPDIIVSTPSRALTHLEANNLVLKDSLENLIIDEADLVLSFGYEEDVRKILTHLPKIYQSFLMSATFTKEIEQLTALVLRKPAILALDDSKEENDLLSQYVVKCTEFEKFLFTFVIIKLRLIKGKILLFVNDIDRCYKLKLFLEQFSIKSCVLNSELPLNSRYHIVEEFNRGIYDYLIATDESELKGEQDSDDEQEDEEKEDDEASSDDEKKNGLSKHVLAKTKKGSKVQKDKEYGVSRGVDFQGVAAVINFDFPSSSKAYTHRIGRTARGGQRGMSLSFVVTKDLVEERKEVARGKNITDEAVYNRVQKQQEAKGAELKPYSFEKKNVAGFKYRVEGALKAVNKVAIKEARIKEIKREIMNSEKLKAHFEDKPKDLEFLRHDHALQPARVQDHLKHIPSYLMPRIAVPTAMANTEPIDVPFQSQKRKRGSFKKGPNKKRKDPLKVIRRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N7P2</accession>
    <name>A0A1C7N7P2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Charged multivesicular body protein 6</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">CHMP6</name>
        <name evidence="9" type="ORF">A0J61_06794</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endosome membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SNF7 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000427">
        <property type="protein sequence ID" value="OBZ85153.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N7P2"/>
    <dbReference type="FunCoup" id="A0A1C7N7P2">
        <property type="interactions" value="403"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N7P2"/>
    <dbReference type="InParanoid" id="A0A1C7N7P2"/>
    <dbReference type="OrthoDB" id="441172at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000815">
        <property type="term" value="C:ESCRT III complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005771">
        <property type="term" value="C:multivesicular body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043328">
        <property type="term" value="P:protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006900">
        <property type="term" value="P:vesicle budding from membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.1060">
        <property type="entry name" value="ESAT-6-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005024">
        <property type="entry name" value="Snf7_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22761">
        <property type="entry name" value="CHARGED MULTIVESICULAR BODY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22761:SF5">
        <property type="entry name" value="CHARGED MULTIVESICULAR BODY PROTEIN 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03357">
        <property type="entry name" value="Snf7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0967">Endosome</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0653">Protein transport</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="164"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="20"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="195"/>
            <end position="210"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004608"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022753"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OBZ85153.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="210" mass="23904" checksum="CDDC8E5CC1A4E83D" modified="2016-11-30" version="1">MGAGASKNKITSQDKAILDLKVQRDKLKRYQKNINKVIEKEIEAAKLALQQDNKQKALLALKKKKYQVQLLEKTDQQLLNLEELTHSIEYALVEKQVLEGLQKGNDVLKEIHKETSLEAVEKLMDDTADAIAYQNEIDEMLHGLISAEDEEEIERELEALREEEIDAELPEVPANKLPEPVVDHEIPSVPTHVPKQAEKPRKEKQAMMAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N801</accession>
    <name>A0A1C7N801_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Serine aminopeptidase S33 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_06718</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000419">
        <property type="protein sequence ID" value="OBZ85232.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N801"/>
    <dbReference type="FunCoup" id="A0A1C7N801">
        <property type="interactions" value="188"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N801"/>
    <dbReference type="InParanoid" id="A0A1C7N801"/>
    <dbReference type="OrthoDB" id="10249433at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022742">
        <property type="entry name" value="Hydrolase_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051044">
        <property type="entry name" value="MAG_DAG_Lipase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11614">
        <property type="entry name" value="PHOSPHOLIPASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12146">
        <property type="entry name" value="Hydrolase_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Serine aminopeptidase S33" evidence="1">
        <location>
            <begin position="27"/>
            <end position="268"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ85232.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="292" mass="32671" checksum="E9CD702743808181" modified="2016-11-30" version="1">MVTVTKDWIKTKDNHEIFTMTWKPDSEPIATLVVIHGFGDHIARYDRMLKEFANHGIQSYGYDQRGWGETAKKSQQLGNNQGYDKALQDIDNAVLTTKKDKVPHFLMGHSMGGGLILNYLARGDKFKGVSTLTGAIASAPLVTLSMPISAFRYYSLRAMSTVVPGVTIQTKVDPKGISRDQDEVNAYINDPLVSDYATLSTLRSFIDAGSDILKSKAKLIKTPILYSHSDSDPINAHKGTAEAFELTASQDKELKTWNGYYHELHNEKPSDREAVYLCYIQWIKKRCNTSSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N8W9</accession>
    <name>A0A1C7N8W9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Thioredoxin-like fold domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_06357</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000381">
        <property type="protein sequence ID" value="OBZ85582.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N8W9"/>
    <dbReference type="STRING" id="101091.A0A1C7N8W9"/>
    <dbReference type="InParanoid" id="A0A1C7N8W9"/>
    <dbReference type="OrthoDB" id="37297at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02972">
        <property type="entry name" value="DsbA_family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012336">
        <property type="entry name" value="Thioredoxin-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33875:SF2">
        <property type="entry name" value="ACR183CP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33875">
        <property type="entry name" value="OS09G0542200 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13462">
        <property type="entry name" value="Thioredoxin_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin-like fold" evidence="1">
        <location>
            <begin position="9"/>
            <end position="180"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ85582.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="200" mass="22727" checksum="C986E275A4964DCC" modified="2016-11-30" version="1">MALAPQFSGHRLGSIAAAHTIELYLDYVCPFSAKMYKKIRQEVWPYIEQAYPNKVQLIFRQQVQPWHASSTIVHEAAIAVEKVDNKKFFEFSDVLFEKQKDYFDEALETKTRRDVAKELAELAGSVGVSSEKVLELLVNGTDEPKNAGNKVTNDLKLAIRIGRQNGIHVSPTLLLDGIRDDSVSSSWELDQWKEYLKSKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N900</accession>
    <name>A0A1C7N900_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Myb-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_06578</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000403">
        <property type="protein sequence ID" value="OBZ85378.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N900"/>
    <dbReference type="InParanoid" id="A0A1C7N900"/>
    <dbReference type="OrthoDB" id="2282747at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00167">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001005">
        <property type="entry name" value="SANT/Myb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13384">
        <property type="entry name" value="HTH_23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13921">
        <property type="entry name" value="Myb_DNA-bind_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50090">
        <property type="entry name" value="MYB_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Myb-like" evidence="2">
        <location>
            <begin position="190"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="78"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="127"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="163"/>
            <end position="175"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ85378.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="250" mass="28296" checksum="B5EB7BA6708B9BF2" modified="2016-11-30" version="1">MKVQPSSVDKSDAKRWLVIGAYQAGANVKKIARLCGLNQSAVRRIILNFKRTGSPNMPRGLSAQEKSKPFVEYDEQGNLIDSEEDEPPPQTLKEKIKARRPSAKDLIAYVLSKAQQQSSSEEAILFAPQKQDPSSKWRPPTPPRDPIHPEEAQQADQQRRRSILSPPLSEPSISPKTNYDDTVIRGYETWTMEEDKLLMAHVLTRLHGGRWEEASSKLKGKHSPKVCQQRWEVLRNLLMHGANKSGTRGW</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N9C8</accession>
    <name>A0A1C7N9C8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Protein SKT5</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">SKT5_1</name>
        <name evidence="3" type="ORF">A0J61_06712</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000419">
        <property type="protein sequence ID" value="OBZ85239.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N9C8"/>
    <dbReference type="STRING" id="101091.A0A1C7N9C8"/>
    <dbReference type="InParanoid" id="A0A1C7N9C8"/>
    <dbReference type="OrthoDB" id="272077at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051726">
        <property type="entry name" value="Chitin_Synth_Reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006597">
        <property type="entry name" value="Sel1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46430:SF1">
        <property type="entry name" value="CHITIN SYNTHASE REGULATOR SKT5-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46430">
        <property type="entry name" value="PROTEIN SKT5-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08238">
        <property type="entry name" value="Sel1"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SMART" id="SM00671">
        <property type="entry name" value="SEL1"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81901">
        <property type="entry name" value="HCP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="403"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="32"/>
            <end position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ85239.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="439" mass="48502" checksum="B59AE2FAD50E5D34" modified="2016-11-30" version="1">MPQASASMPVLTNQRSGSIKTPSRASSRDHPIISSGSSSSSLSMPTTPSPHTHRYPSTVSSSVSINSDYLMNHSHLKPGTNAELLSYDKTINMYRENAKRTNDPNLQHDLAIFIFESCKNKVMDNKQRLAYLTEAVKMLKTLALRGHADSQYYLANIYASGILHKSGKPNFNGAFPLFVQAAKHQHADAAYRAAKCYEDGLGCLKNKSKAIQYYKLASTLNHPGAMYRLGIAFIHGDLGLQRNVREGNKWLKRSAEAATPEYPHALHEFGLLHEKGLDGIIFKDTSYSVQLYRQAAELGYAPSAYRLGQCYEHGYLGCQPDIIKSMSFYQLAARQEHAEACFALSVLYLTGDPPQLPPSEEKAYHWAKLAALKGLPKAEFALGYYAEMGIGRPKDSQDAMAWYQKAAQHGDERAKKRMSSVQATPPLPSVQPAVAAKVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-06-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N9R8</accession>
    <name>A0A1C7N9R8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_07867</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000557">
        <property type="protein sequence ID" value="OBZ84094.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N9R8"/>
    <dbReference type="InParanoid" id="A0A1C7N9R8"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ84094.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="76" mass="8692" checksum="54FA5A3B3FB69714" modified="2016-11-30" version="1">MLPGNNMIGNRSLKEQKLILESILCMTFFCVSAIKMDRIDLSSKDSNPTAWIDHKISADIYHTYINLIGSYKTIRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N9S4</accession>
    <name>A0A1C7N9S4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">High mobility group-T protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">HMGT_0</name>
        <name evidence="5" type="ORF">A0J61_06110</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000353">
        <property type="protein sequence ID" value="OBZ85841.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N9S4"/>
    <dbReference type="STRING" id="101091.A0A1C7N9S4"/>
    <dbReference type="InParanoid" id="A0A1C7N9S4"/>
    <dbReference type="OrthoDB" id="1919336at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00084">
        <property type="entry name" value="HMG-box_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.30.10">
        <property type="entry name" value="High mobility group box domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009071">
        <property type="entry name" value="HMG_box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036910">
        <property type="entry name" value="HMG_box_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050342">
        <property type="entry name" value="HMGB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48112">
        <property type="entry name" value="HIGH MOBILITY GROUP PROTEIN DSP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00505">
        <property type="entry name" value="HMG_box"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00398">
        <property type="entry name" value="HMG"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47095">
        <property type="entry name" value="HMG-box"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50118">
        <property type="entry name" value="HMG_BOX_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HMG box" evidence="4">
        <location>
            <begin position="127"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="domain" description="HMG box" evidence="4">
        <location>
            <begin position="273"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="HMG box" evidence="2">
        <location>
            <begin position="127"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="HMG box" evidence="2">
        <location>
            <begin position="273"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="101"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="235"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="348"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="260"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="348"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="358"/>
            <end position="367"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OBZ85841.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="393" mass="44965" checksum="0A6E645D7CE81817" modified="2016-11-30" version="1">MLSTLLQHEECKELLDSPPMHIVSPEAIQEAMKEEKEEAMGHSQRRPFSRFASINALKQRIPFVGLPPSLPANVPITTNLPSSTIIPPISIAHSSFTLPNIKEEDEDSDGTKATVSSSTKARKSEKPKRPPNAYLLFNRDMRRKLLQTSPRMTVAEISKEIGDNWKVLPNDQRSRYVQEASILKQEHLKKHPDFIYTRRSKAELAEAKRNPKPNKQNSTSKQTFSLIQAMPADNSKSTLVIENSRRKAKRSLLNGQKDPRGRKKKRYKHPFAPKHPMSAYLHYLASVYPQVSAKFPGSTVGPISKSISRTWHAMSAEERLPWKQKADSDKARYAQEMKVYMAKNDLDKHEEKLSHASDEEEEEEGEANEIQYFHSQVFYRLSDEMNNKHVNLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NAV9</accession>
    <name>A0A1C7NAV9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">CigA protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">A0J61_05692</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000315">
        <property type="protein sequence ID" value="OBZ86255.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NAV9"/>
    <dbReference type="STRING" id="101091.A0A1C7NAV9"/>
    <dbReference type="InParanoid" id="A0A1C7NAV9"/>
    <dbReference type="OrthoDB" id="1882547at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006004">
        <property type="term" value="P:fucose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd11296">
        <property type="entry name" value="O-FucT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11350">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019378">
        <property type="entry name" value="GDP-Fuc_O-FucTrfase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36050">
        <property type="entry name" value="O-FUCOSYLTRANSFERASE 30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36050:SF1">
        <property type="entry name" value="O-FUCOSYLTRANSFERASE 30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10250">
        <property type="entry name" value="O-FucT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="2" id="KW-0294">Fucose metabolism</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="21"/>
            <end position="40"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023253"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OBZ86255.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="526" mass="60992" checksum="72B9106830F9F42B" modified="2016-11-30" version="1">MSKKAHPLDILTTSKQRNKRGGIAVGILLSCLALVYWIYFQSSSVRRDDPVQKESIPPLKQDVTEPVIPVIYPDPFAFHTITPEERYVTYLPHSGFHNQRIELENAFLLAAYLNRTLLLPSVYLGNPAFPWLRFDKMYERLLLQTKNGLDYCSQIRDDEPMPSECLTYKQWTAIPWTFFYDFKELRKHVRIVFRDDLSLEWIQDHLNATEQDIYLFKDYSPFDYRIYDLAESKTPLTRFVHRIELEALEAIEEKVLHFGSVFGSYRVLAQTEDHRDFFKLVRKDMIFTNPTLMTVAERIVKKLGGVGSFVGLHVRVGDGLFKVRASIQIDDLFHRLVDDFTDLMESELKNIYDRDHDQDRKENNEYEIRQLREDYQNATDGFDMPIRVQHPADNQESLGPASDSLQLSCQVGDGRNDRFAKTTVFIATDCPQPRAHPLLRKLFAVFPCTFVLSDFKDDLSELSQIEVMQEKVKLESYLIPMVDAIISAQGHTFYGTNSSTFSTYIERQLHPAYTNQPIELLGAPSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NB51</accession>
    <name>A0A1C7NB51_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 10">Orotidine 5'-phosphate decarboxylase</fullName>
            <ecNumber evidence="3 10">4.1.1.23</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">pyrG</name>
        <name evidence="12" type="ORF">A0J61_05598</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>orotidine 5'-phosphate + H(+) = UMP + CO2</text>
            <dbReference type="Rhea" id="RHEA:11596"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:57538"/>
            <dbReference type="ChEBI" id="CHEBI:57865"/>
            <dbReference type="EC" id="4.1.1.23"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 10">Pyrimidine metabolism; UMP biosynthesis via de novo pathway; UMP from orotate: step 2/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the OMP decarboxylase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.1.1.23" evidence="3 10"/>
    <dbReference type="EMBL" id="LUGH01000307">
        <property type="protein sequence ID" value="OBZ86352.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NB51"/>
    <dbReference type="FunCoup" id="A0A1C7NB51">
        <property type="interactions" value="980"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NB51"/>
    <dbReference type="InParanoid" id="A0A1C7NB51"/>
    <dbReference type="OrthoDB" id="10263753at2759"/>
    <dbReference type="UniPathway" id="UPA00070">
        <property type="reaction ID" value="UER00120"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004588">
        <property type="term" value="F:orotate phosphoribosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004590">
        <property type="term" value="F:orotidine-5'-phosphate decarboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006207">
        <property type="term" value="P:'de novo' pyrimidine nucleobase biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044205">
        <property type="term" value="P:'de novo' UMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd04725">
        <property type="entry name" value="OMP_decarboxylase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.70:FF:000114">
        <property type="entry name" value="Decarboxylase,orotidine phosphate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014732">
        <property type="entry name" value="OMPdecase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018089">
        <property type="entry name" value="OMPdecase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001754">
        <property type="entry name" value="OMPdeCOase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011060">
        <property type="entry name" value="RibuloseP-bd_barrel"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01740">
        <property type="entry name" value="pyrF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19278">
        <property type="entry name" value="OROTATE PHOSPHORIBOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19278:SF9">
        <property type="entry name" value="URIDINE 5'-MONOPHOSPHATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00215">
        <property type="entry name" value="OMPdecase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00934">
        <property type="entry name" value="OMPdecase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51366">
        <property type="entry name" value="Ribulose-phoshate binding barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00156">
        <property type="entry name" value="OMPDECASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 10" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="7 10" id="KW-0456">Lyase</keyword>
    <keyword evidence="6 10" id="KW-0665">Pyrimidine biosynthesis</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Orotidine 5'-phosphate decarboxylase" evidence="11">
        <location>
            <begin position="32"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="active site" description="For OMPdecase activity" evidence="8">
        <location>
            <position position="91"/>
        </location>
    </feature>
    <feature type="active site" description="For OMPdecase activity" evidence="8">
        <location>
            <position position="93"/>
        </location>
    </feature>
    <feature type="active site" description="For OMPdecase activity" evidence="8">
        <location>
            <position position="96"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="38"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="60"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="151"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="211"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="231"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="232"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004861"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011018"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012321"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00021923"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR614732-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR614732-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000512"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM00934"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="OBZ86352.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="266" mass="29618" checksum="DCDA057241E78999" modified="2016-11-30" version="1">MNTYKTYSERAKQHPNACARSLFELMERKQSNLSVAVDVTTKKELLSIADSVGPYVCVLKTHIDIVEDFDADLVEQLQKLAKKHDFLIFEDRKFADIGNTVKHQYGKGVYKIASWSHITNAHTVPGEGIIKGLAEVGLPLGRGLLLLAEMSSQGALTKGSYTTESVEMARRNKDFVFGFIAQHKMNQFDDEDFVVMSPGVGLDVKGDGLGQQYRTPHQVIVESGGDVIIVGRGIYGQPDQVEAQAQRYRQAGWDAYLERVSLHNKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NBG3</accession>
    <name>A0A1C7NBG3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Lysine-specific permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">lysP_5</name>
        <name evidence="9" type="ORF">A0J61_05861</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000329">
        <property type="protein sequence ID" value="OBZ86089.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NBG3"/>
    <dbReference type="FunCoup" id="A0A1C7NBG3">
        <property type="interactions" value="426"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NBG3"/>
    <dbReference type="InParanoid" id="A0A1C7NBG3"/>
    <dbReference type="OrthoDB" id="3900342at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015171">
        <property type="term" value="F:amino acid transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1740.10:FF:000001">
        <property type="entry name" value="Amino acid permease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1740.10">
        <property type="entry name" value="Amino acid/polyamine transporter I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004841">
        <property type="entry name" value="AA-permease/SLC12A_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004840">
        <property type="entry name" value="Amino_acid_permease_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050524">
        <property type="entry name" value="APC_YAT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43341">
        <property type="entry name" value="AMINO ACID PERMEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43341:SF1">
        <property type="entry name" value="GENERAL AMINO-ACID PERMEASE GAP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00324">
        <property type="entry name" value="AA_permease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006060">
        <property type="entry name" value="AA_transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00218">
        <property type="entry name" value="AMINO_ACID_PERMEASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0029">Amino-acid transport</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="44"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="74"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="122"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="153"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="183"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="224"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="266"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="314"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="365"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="398"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="437"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="470"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="domain" description="Amino acid permease/ SLC12A" evidence="8">
        <location>
            <begin position="43"/>
            <end position="498"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OBZ86089.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="543" mass="58642" checksum="85280893A80E4DD7" modified="2016-11-30" version="1">MHQEKDKVQVGEQTIVEDVQSFTSADSTAEKTHSLQRNLKARHIQMIALGGTIGTGLFISSGKAINAGGPGGALIGYGLVGILVYIVMMSLGEMAAFIPVAGSFSHFATRFADPSLGFMVGWIYWANWAVGVAVELTGVAVIMEYWVRNINSVIWSVICLVILVGINVFSVKGYGEIEYWISMIKILVVVIFIIVGLCVDTGALGGVNIGVTNFHLEGGAFPQGFLGVFNVFITAAFSYNGVEIAGITAGESANPHKTVPSAVKQVFIRIVLFYVLSILVIGLCIPYTDPNLLSASSHNISVSPFTLVFKKAGAAWAADMMNAIILITMISAGNSGVYSSSRTLMSLANDGYAPRFFTRVNRWGIPIWSVLATCAIGCLAFLTSLFGSGVVFNWLTRLTSLAGLITWVSICITHLRFRRGYIAQGRSLTSLPYVAPLYPYCDILVIVIGTIIIFGQGYSSFIAPINGSDIVSTYIGLILAVVLYAAHKLWKRDGFVKCPDMDFETGTLQQTVIDIRQDEGLDKNGNPIPRWKRVLGKIVSIIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NBJ1</accession>
    <name>A0A1C7NBJ1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Synaptobrevin homolog YKT6</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">A0J61_05820</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Endomembrane system</location>
            <topology evidence="8">Single-pass type IV membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the synaptobrevin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000326">
        <property type="protein sequence ID" value="OBZ86129.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NBJ1"/>
    <dbReference type="STRING" id="101091.A0A1C7NBJ1"/>
    <dbReference type="InParanoid" id="A0A1C7NBJ1"/>
    <dbReference type="OrthoDB" id="248747at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016192">
        <property type="term" value="P:vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd14824">
        <property type="entry name" value="Longin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd15843">
        <property type="entry name" value="R-SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.450.50:FF:000015">
        <property type="entry name" value="Synaptobrevin 2 isoform 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.5.110:FF:000004">
        <property type="entry name" value="Vesicle-associated membrane protein 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.50">
        <property type="entry name" value="Longin domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011012">
        <property type="entry name" value="Longin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010908">
        <property type="entry name" value="Longin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001388">
        <property type="entry name" value="Synaptobrevin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051097">
        <property type="entry name" value="Synaptobrevin-like_transport"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042855">
        <property type="entry name" value="V_SNARE_CC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21136">
        <property type="entry name" value="SNARE PROTEINS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21136:SF168">
        <property type="entry name" value="VESICLE-ASSOCIATED MEMBRANE PROTEIN 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13774">
        <property type="entry name" value="Longin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00957">
        <property type="entry name" value="Synaptobrevin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00219">
        <property type="entry name" value="SYNAPTOBREVN"/>
    </dbReference>
    <dbReference type="SMART" id="SM01270">
        <property type="entry name" value="Longin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF58038">
        <property type="entry name" value="SNARE fusion complex"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64356">
        <property type="entry name" value="SNARE-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50859">
        <property type="entry name" value="LONGIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00417">
        <property type="entry name" value="SYNAPTOBREVIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50892">
        <property type="entry name" value="V_SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0653">Protein transport</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="189"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="domain" description="Longin" evidence="11">
        <location>
            <begin position="7"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="domain" description="V-SNARE coiled-coil homology" evidence="12">
        <location>
            <begin position="125"/>
            <end position="185"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008025"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00026133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00046280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50859"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="OBZ86129.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="219" mass="25094" checksum="68B739AF313E5DBA" modified="2016-11-30" version="1">MSLIYGLVARGSTILAEHTTSNGNYGTVTQAILEKIPPNNSKLTYVYDRYLFHYICEDGIIYMCMADDTFGRRIPFVFLQDLKDKFLTTYGKSRALDAPPFGLNEFSRVIEKQMEYFSTNPGADRLKQVHGEIEQVKDVMVHNIERVLERGERIELLVDKTDNLNQQAFAFKKRSTQLKRAMWWKNTKIMAMIGLVCFLIAYFIAASVCGFPAFGQCRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NC32</accession>
    <name>A0A1C7NC32_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Arrestin domain-containing protein C31A2.12</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_05809</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000325">
        <property type="protein sequence ID" value="OBZ86146.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NC32"/>
    <dbReference type="InParanoid" id="A0A1C7NC32"/>
    <dbReference type="OrthoDB" id="2333384at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030674">
        <property type="term" value="F:protein-macromolecule adaptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031625">
        <property type="term" value="F:ubiquitin protein ligase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070086">
        <property type="term" value="P:ubiquitin-dependent endocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.640">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014752">
        <property type="entry name" value="Arrestin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011022">
        <property type="entry name" value="Arrestin_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050357">
        <property type="entry name" value="Arrestin_domain-protein"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11188">
        <property type="entry name" value="ARRESTIN DOMAIN CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11188:SF17">
        <property type="entry name" value="FI21816P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02752">
        <property type="entry name" value="Arrestin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01017">
        <property type="entry name" value="Arrestin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Arrestin C-terminal-like" evidence="1">
        <location>
            <begin position="164"/>
            <end position="305"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM01017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ86146.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="371" mass="42184" checksum="63813E25E0C748A8" modified="2016-11-30" version="1">MVYKVANRPSNKLKIHVESSQLVMYGSSTESSGCVLRGALSLRLKKPSRFVSLALCFYGSISVSWNQCKLAKIYFYIKRYKPNKIHLLEAGHHTYEFELALPGNLPESTHVAKHYISQYHLKASAQRAGILSLNYTTQQDIHLSRQNFSLGTEYFDPMTVVNVCPGKISYDISMPTKVYGHGDTVPITVRAVLLSPNVQLRYVSCIFKEYVTCRPINGWYNGKNKSYSHMIQYTRQPIEQQRDHSYTVVLHTKIPDSFAEIQCDAQNDSVRVKHKLKFILSIEDQNGNRSEVKATMXIVVAVTCIMGGLPAYNDIWKTMPYDPVLMMALIRRENSDLHHYAFHPIHHRQNNEVSSCLPSYSSIMATAEAIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NC64</accession>
    <name>A0A1C7NC64_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">G1/S-specific cyclin pas1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">pas1_5</name>
        <name evidence="1" type="ORF">A0J61_05289</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000282">
        <property type="protein sequence ID" value="OBZ86661.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NC64"/>
    <dbReference type="FunCoup" id="A0A1C7NC64">
        <property type="interactions" value="5"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NC64"/>
    <dbReference type="InParanoid" id="A0A1C7NC64"/>
    <dbReference type="OrthoDB" id="286814at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000307">
        <property type="term" value="C:cyclin-dependent protein kinase holoenzyme complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016538">
        <property type="term" value="F:cyclin-dependent protein serine/threonine kinase regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019901">
        <property type="term" value="F:protein kinase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd20557">
        <property type="entry name" value="CYCLIN_ScPCL1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.10">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036915">
        <property type="entry name" value="Cyclin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013922">
        <property type="entry name" value="Cyclin_PHO80-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15615">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15615:SF36">
        <property type="entry name" value="PHO85 CYCLIN-5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08613">
        <property type="entry name" value="Cyclin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47954">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ86661.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="218" mass="25367" checksum="7B021B92EA2C639C" modified="2016-11-30" version="1">MTTKDTTQLLRTNDLTQYQKIYVDTLIDITTLTIRTSWPMEASTTKEGQPVVNTNLFVRHLLKRSRATRSTLQLAIFYLFRIRPFICKRSQFDPIVKCGRRMFLASLICAHKYLYDNTFTNASWAKISKLPVKEINGAERALLDMLDYRLHISLELYQKFESQLREAVPSHASIPTSHPLVGQKRSVEQELTTVKRHRQHYHTVYGIPTPEDDKVELV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NCB4</accession>
    <name>A0A1C7NCB4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_05240</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000278">
        <property type="protein sequence ID" value="OBZ86711.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NCB4"/>
    <dbReference type="InParanoid" id="A0A1C7NCB4"/>
    <dbReference type="OrthoDB" id="10373301at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019005">
        <property type="term" value="C:SCF ubiquitin ligase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031146">
        <property type="term" value="P:SCF-dependent proteasomal ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13318">
        <property type="entry name" value="PARTNER OF PAIRED, ISOFORM B-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ86711.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="565" mass="65212" checksum="8278A6997C137BA9" modified="2016-11-30" version="1">MPRTIPHKVLRRIGAYLSKEEYYQLIFVNHLFYYIYIEFLLHTVKVHTVNQLSQFMNQTKNHRFVEHLEIYSNEMRGSDLKKMRQSLSCLRSVRFNLSSCDSASFEAYFSLRNITSITLDGLPKSIYAVTDLSFPHQLKSLTLQIGSALKVNADLLEHIYAECPILEYLSVGGNYGSMSEAEQSDRYLATNTIKELELKAECGLGDIHIWFTYIGNRFPNLTSLKLKYCSDSFDISQFTNADNKMPGTFYDWFLSGCPILTCIETENILLDQAFFRQWKTQQGVNVASIISNAGTKTVFLEACKLDWTDFLALTKLDICFFYDTVKNGLIATIAKASPNLTQLILRRAKLFQNGTLWIGAILHGFPHLKYLGLVKANLSANPHILEKDNDAWHPLEKVYIEDCNLHEGFFGCVSIRCLELQHVSFIGTRFKYQHYKGHLDLRQQNMHTVDLQCPRISNLNQVIRLFNVRRQTTSEWYYMRKYRTPHGTLMEAAESFEKLNETNTLLLDVMLSQHPSSWEDLVTNAYLHTSDLLEGIHLPKALSAGYFEIKCHSLRALRINHKHIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NDD2</accession>
    <name>A0A1C7NDD2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Serine/threonine-protein phosphatase 2A activator</fullName>
            <ecNumber evidence="7">5.2.1.8</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Phosphotyrosyl phosphatase activator</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">PPP2R4</name>
        <name evidence="8" type="ORF">A0J61_05183</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 10">
            <text>[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)</text>
            <dbReference type="Rhea" id="RHEA:16237"/>
            <dbReference type="Rhea" id="RHEA-COMP:10747"/>
            <dbReference type="Rhea" id="RHEA-COMP:10748"/>
            <dbReference type="ChEBI" id="CHEBI:83833"/>
            <dbReference type="ChEBI" id="CHEBI:83834"/>
            <dbReference type="EC" id="5.2.1.8"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 7">Belongs to the PTPA-type PPIase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.2.1.8" evidence="7"/>
    <dbReference type="EMBL" id="LUGH01000273">
        <property type="protein sequence ID" value="OBZ86769.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NDD2"/>
    <dbReference type="FunCoup" id="A0A1C7NDD2">
        <property type="interactions" value="217"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NDD2"/>
    <dbReference type="InParanoid" id="A0A1C7NDD2"/>
    <dbReference type="OrthoDB" id="16120at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000785">
        <property type="term" value="C:chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000159">
        <property type="term" value="C:protein phosphatase type 2A complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008160">
        <property type="term" value="F:protein tyrosine phosphatase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006914">
        <property type="term" value="P:autophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000082">
        <property type="term" value="P:G1/S transition of mitotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007052">
        <property type="term" value="P:mitotic spindle organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd04087">
        <property type="entry name" value="PTPA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.120.1150:FF:000002">
        <property type="entry name" value="Serine/threonine-protein phosphatase 2A activator"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004327">
        <property type="entry name" value="Phstyr_phstse_ac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043170">
        <property type="entry name" value="PTPA_C_lid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037218">
        <property type="entry name" value="PTPA_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10012">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN PHOSPHATASE 2A REGULATORY SUBUNIT B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10012:SF0">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN PHOSPHATASE 2A ACTIVATOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03095">
        <property type="entry name" value="PTPA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016325">
        <property type="entry name" value="Phstyr_phstse_ac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140984">
        <property type="entry name" value="PTPA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 7" id="KW-0413">Isomerase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7" id="KW-0697">Rotamase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU361210"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OBZ86769.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="308" mass="35330" checksum="5AC2A895AC50C830" modified="2016-11-30" version="1">MLQLPNISQDYQPQEPIACIQTQRDIDRFVQTKAFERIMTFVALLNDSVMGSKVSDPCFISTQTQSILDLLTTLDSWVDAIPPLDQPQRFGNKAFRQFILRLQQSSDRLQREALPESMHLALPELTEYLVHGFGNETRIDYGSGHELSFVAWLAGIAMLGGFEPEDYQAIVLRIFVQYLELVRKIQKRYTLEPAGSHGVWGLDDHQFLPYVWGSAQLINHPQLKPNAIQSKDTVHAMAADYMYFRCIQFILEVKRGPFFEHSPMLNDIASVISWSKVNSGMTKMFIAEVLKKVPVVQHFKFGRLFPFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NDP6</accession>
    <name>A0A1C7NDP6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Pepsin-2B</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">PEP2B</name>
        <name evidence="4" type="ORF">A0J61_04735</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase A1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000238">
        <property type="protein sequence ID" value="OBZ87217.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NDP6"/>
    <dbReference type="STRING" id="101091.A0A1C7NDP6"/>
    <dbReference type="InParanoid" id="A0A1C7NDP6"/>
    <dbReference type="OrthoDB" id="2747330at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004190">
        <property type="term" value="F:aspartic-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05471">
        <property type="entry name" value="pepsin_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.70.10">
        <property type="entry name" value="Acid Proteases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001461">
        <property type="entry name" value="Aspartic_peptidase_A1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034164">
        <property type="entry name" value="Pepsin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033121">
        <property type="entry name" value="PEPTIDASE_A1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021109">
        <property type="entry name" value="Peptidase_aspartic_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47966">
        <property type="entry name" value="BETA-SITE APP-CLEAVING ENZYME, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47966:SF51">
        <property type="entry name" value="BETA-SITE APP-CLEAVING ENZYME, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00026">
        <property type="entry name" value="Asp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00792">
        <property type="entry name" value="PEPSIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50630">
        <property type="entry name" value="Acid proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51767">
        <property type="entry name" value="PEPTIDASE_A1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase A1" evidence="3">
        <location>
            <begin position="16"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="2">
        <location>
            <begin position="293"/>
            <end position="332"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR601461-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51767"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OBZ87217.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="381" mass="42608" checksum="90A9A8544149A47A" modified="2016-11-30" version="1">MKFPNFGKKPPKLPLTYIQGVVSTPSQEFIGVFDTASSISWVASDQCQSRACLNSFDDRKFHSRESYTNLKFPFFVDLSYIDGTHIRIKPELDVLTFGGFSLPPHLIGEAFEIDYPKGYLPPANARIGMGGFGSIDWIKTGLSIDRNALPLISHIFKNKRAVGDDRFSTGYISSGSENFRKRGPVQSELFESFAWIVGVDKSLYHGPIYDLSLAPMHGLRSPFWNIPILGIDFQYNNRTSGNTTFSFKLASNAYGKVYSSSPMLTVPEEIAEKMNTALGAVYDENLNIYTISCSAYLTAPNLVFRFDDGVHAEIPPEQFIYRLEQRSKTKGCYTAIAGGPDSSRIFLGGPFFRSFYLVYQFRNFKVGIAESIAKAGKVYKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NDV5</accession>
    <name>A0A1C7NDV5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">2-oxoglutarate dehydrogenase, mitochondrial</fullName>
            <ecNumber evidence="5">1.2.4.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="15">2-oxoglutarate dehydrogenase complex component E1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="19" type="primary">kgd1</name>
        <name evidence="19" type="ORF">A0J61_04670</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="19 20" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19 20">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components: 2-oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="16">
            <text>N(6)-[(R)-lipoyl]-L-lysyl-[protein] + 2-oxoglutarate + H(+) = N(6)-[(R)-S(8)-succinyldihydrolipoyl]-L-lysyl-[protein] + CO2</text>
            <dbReference type="Rhea" id="RHEA:12188"/>
            <dbReference type="Rhea" id="RHEA-COMP:10474"/>
            <dbReference type="Rhea" id="RHEA-COMP:20092"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:83099"/>
            <dbReference type="ChEBI" id="CHEBI:83120"/>
            <dbReference type="EC" id="1.2.4.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>thiamine diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58937"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Mitochondrion matrix</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the alpha-ketoglutarate dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="19">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.2.4.2" evidence="5"/>
    <dbReference type="EMBL" id="LUGH01000233">
        <property type="protein sequence ID" value="OBZ87277.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NDV5"/>
    <dbReference type="FunCoup" id="A0A1C7NDV5">
        <property type="interactions" value="248"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NDV5"/>
    <dbReference type="InParanoid" id="A0A1C7NDV5"/>
    <dbReference type="OrthoDB" id="413077at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042645">
        <property type="term" value="C:mitochondrial nucleoid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045252">
        <property type="term" value="C:oxoglutarate dehydrogenase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004591">
        <property type="term" value="F:oxoglutarate dehydrogenase (succinyl-transferring) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030976">
        <property type="term" value="F:thiamine pyrophosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006103">
        <property type="term" value="P:2-oxoglutarate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02016">
        <property type="entry name" value="TPP_E1_OGDC_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.1150:FF:000002">
        <property type="entry name" value="2-oxoglutarate dehydrogenase E1 component"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.11610:FF:000009">
        <property type="entry name" value="2-oxoglutarate dehydrogenase E1 component"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.12470:FF:000003">
        <property type="entry name" value="2-oxoglutarate dehydrogenase E1 component"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.970:FF:000002">
        <property type="entry name" value="2-oxoglutarate dehydrogenase, E1 component"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12470">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.970">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11610">
        <property type="entry name" value="Multifunctional 2-oxoglutarate metabolism enzyme, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.1150">
        <property type="entry name" value="TPP helical domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032106">
        <property type="entry name" value="2-oxogl_dehyd_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011603">
        <property type="entry name" value="2oxoglutarate_DH_E1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001017">
        <property type="entry name" value="DH_E1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042179">
        <property type="entry name" value="KGD_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031717">
        <property type="entry name" value="ODO-1/KGD_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029061">
        <property type="entry name" value="THDP-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005475">
        <property type="entry name" value="Transketolase-like_Pyr-bd"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00239">
        <property type="entry name" value="2oxo_dh_E1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006914">
        <property type="entry name" value="PRK09404.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF008907">
        <property type="entry name" value="PRK12270.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23152:SF4">
        <property type="entry name" value="2-OXOADIPATE DEHYDROGENASE COMPLEX COMPONENT E1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23152">
        <property type="entry name" value="2-OXOGLUTARATE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16078">
        <property type="entry name" value="2-oxogl_dehyd_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00676">
        <property type="entry name" value="E1_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16870">
        <property type="entry name" value="OxoGdeHyase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02779">
        <property type="entry name" value="Transket_pyr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000157">
        <property type="entry name" value="Oxoglu_dh_E1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00861">
        <property type="entry name" value="Transket_pyr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52518">
        <property type="entry name" value="Thiamin diphosphate-binding fold (THDP-binding)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="10" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0786">Thiamine pyrophosphate</keyword>
    <keyword evidence="9" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="6" id="KW-0816">Tricarboxylic acid cycle</keyword>
    <feature type="domain" description="Transketolase-like pyrimidine-binding" evidence="18">
        <location>
            <begin position="647"/>
            <end position="857"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="969"/>
            <end position="995"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004305"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00006936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00037426"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00040267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00042984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00051911"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="SMART" id="SM00861"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="OBZ87277.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="1028" mass="115305" checksum="565624AE1105174D" modified="2016-11-30" version="1">MYRLSTLSRVSRTLRPSVQAVPQATRQSIFRASVAPFHTTRTRRAAPETNDGFLHGSSANYIEEMYEAWLKDPSSVHLSWQVYFKNMANGVSPGQAYSPPPTLVPSASARLPVLPGEGAAAGSDVIDHMKIQLLTRAYQVRGHHIANLDPLGILHADLNSSTPPELEYTYYGFKDSDLDRTFTIGPGILPAFTKSGATLTLREIIAHLKKIYCGSIGVEYIHIPDRAQCDWIRERIETPQPYKYSVEEKRVILDRLTWSDSFERFVASKYPSEKRFGLEGGETLIPGMKAMIDRSVDLGVESIVIGMPHRGRLNVLSNVVRKPAESIFCEFSGTAPSEEGSGDVKYHLGMNYVRPTPSGKRVHLSLVANPSHLEAVDPVVLGKTRALQFYSKDIKGDKSMAVLIHGDAAFAGQGVVYETMGFHDLPSYSTGGTIHVVVNNQIGFTTDPRYGRSTPYCTDIAKAINAPIFHVNGDDAEAVTYVMQLAADWRQTFHKDVVIDLVCYRKHGHNETDQPMFTQPRMYEAIAKQKPVAQKYETQLKEEGSLTDAEIKDNKKRVWDILEESYARSKDYKPTSTEWQSSSWPGFKSPKELAEENLPHYPTGVSPEALSTVGNALTTLPHNFNIHRNLKRILQNREKSLTSGKDIDWSTAEALAWGTLLAEGKHVRISGQDVERGTFSQRHAVLHDQKDGSKHTLLNHISPEQGVLSISNSSLSEYGVLGFELGYSLVNPDSLVVWEAQFGDFANTAQVIVDQFLAAGEQKWLQRSGLVMSLPHGYDGQGPEHSSARIERYLQMCDDYPYTYPSPEKLSRQHQDCNMQVVYASTPSQYFHVLRRQICRQFRKPLIMPFSKSLLRHPLVKSDIDELIGDTHFQLYLPEEHPEHLVAPEKIKKHILCTGQVYYNLLKARDQNKIDDVAISRVEQLNPFPYEQVKEHADKYPNAEIIWCQEEPLNMGAWQHVQPRIATSLSQTEHHAGKSPRYAGRAPSASVATGNKKKHLQEEYGLLAEALTGESRQPKEITSGVPVW</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NE44</accession>
    <name>A0A1C7NE44_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_04738</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000238">
        <property type="protein sequence ID" value="OBZ87210.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NE44"/>
    <dbReference type="InParanoid" id="A0A1C7NE44"/>
    <dbReference type="OrthoDB" id="2284923at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ87210.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="108" mass="12061" checksum="E7A9D2AC024A9C3F" modified="2016-11-30" version="1">MFGCMLDDSWAEEAVGVKISNENEVVSRISSLSSNGASTGPPPFWSALLQLLYAIDSLVHPLVTSLLNPILTDRGFLYRPHRPHRRRNDLFSLLIAQPRCSYNSTYAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NEX1</accession>
    <name>A0A1C7NEX1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">N-alpha-acetyltransferase 25, NatB auxiliary subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">Naa25</name>
        <name evidence="3" type="ORF">A0J61_04278</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the MDM20/NAA25 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000205">
        <property type="protein sequence ID" value="OBZ87673.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NEX1"/>
    <dbReference type="FunCoup" id="A0A1C7NEX1">
        <property type="interactions" value="711"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NEX1"/>
    <dbReference type="InParanoid" id="A0A1C7NEX1"/>
    <dbReference type="OrthoDB" id="1874341at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031416">
        <property type="term" value="C:NatB complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.1040">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019183">
        <property type="entry name" value="NAA25_NatB_aux_su"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22767:SF3">
        <property type="entry name" value="N-ALPHA-ACETYLTRANSFERASE 25, NATB AUXILIARY SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22767">
        <property type="entry name" value="N-TERMINAL ACETYLTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09797">
        <property type="entry name" value="NatB_MDM20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="142"/>
            <end position="164"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006298"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ87673.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="901" mass="104262" checksum="6183914DA1E63B35" modified="2016-11-30" version="1">MDYTTEKKLRPLYEALDEGQNKSALQHCTKLLKKNPDWPLVKALKALVLVRIGKEDEALEICEQVKKVIPTDEPTLQAVTMALKELGKHTMIVELYENASNIQPKNEEFANHWFMAMVRNSDYKGQQAAAVKLHRLFKQNKYLFWAIMSLALQGANNPLSYVLAERMMAKALEENRLDQVEHMRLYLLILMDQNKKEEALKLLMADTKLSQTALKDPEVNQIQSELLRDNQQWDSVLEMSQKALQENADDWFHWLAYFDAVDALHQDDHVVQQARELIARSQAAELEKKVLKRGPFLAELELEYRLHKIGKQDESVMLDHIVSYFKRFGSKNCAFEDLHTYMSFLQSDKKRSMQLVKRFEETIDSTSEKSSQIKNVYKLANIQKIQRFLGLHAADNIKDSMTIVNSLFESYRQALPLGEGLEKTELQYGDDFVILAAHLLLDLYHHHQQTVFLLQAITILESALLKSVYNFQIKLLLVRIYIMCGVYKRPFEIYRSMEIKQIQFDTMIHYFTDRYASLGCASELETLMYDSLSIYKSNEVETPEMLVKAYQYGTFSKIQEFIEFRHRLDASLQHTITRIELLRLEFIHSSFQTKYAIQYFQEQDVSKLVLDEKQLSDNRDRKVFINFNATNQPTAEATSKPAPSTDSIWAQVMSFILTILHIMCETKDSGRDLATYLENFKTLLEKEDTKSHLTTCEFWLSQYFIALTNALVLSKQNQDVTGKLEEATAILRDECKFADLTFWYFIVAYTMSKIDAFSDKNLCWNTFHQISTSLEAFNYGSVVIEMISRTLGLSSKEAKRKAAENAGSNPLMAAYTGLLAQVKASLQQIQTIARNGKEVFRSQLQKKLCKDLLDAEHNITALKDIKEYQNVATNHIKTMVQSWSLSVTELSEEIDRRVQKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NF95</accession>
    <name>A0A1C7NF95_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">F-box/LRR-repeat protein 7</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">FBXL7</name>
        <name evidence="2" type="ORF">A0J61_04157</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000197">
        <property type="protein sequence ID" value="OBZ87783.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NF95"/>
    <dbReference type="STRING" id="101091.A0A1C7NF95"/>
    <dbReference type="InParanoid" id="A0A1C7NF95"/>
    <dbReference type="OrthoDB" id="421226at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019005">
        <property type="term" value="C:SCF ubiquitin ligase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031146">
        <property type="term" value="P:SCF-dependent proteasomal ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057135">
        <property type="entry name" value="At4g27190-like_LRR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006553">
        <property type="entry name" value="Leu-rich_rpt_Cys-con_subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13318">
        <property type="entry name" value="PARTNER OF PAIRED, ISOFORM B-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23247">
        <property type="entry name" value="LRR_RPS2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00367">
        <property type="entry name" value="LRR_CC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Disease resistance protein At4g27190-like leucine-rich repeats" evidence="1">
        <location>
            <begin position="96"/>
            <end position="212"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF23247"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ87783.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="236" mass="27274" checksum="9AE125B6883C8791" modified="2016-11-30" version="1">MSVFWPNELLSQVFNYLKEDQATLAQLTLTSKQFRLVALPFLYYAPQWTRLSQIELFASVLNDNTGLMVHRIDLHMVSHRWQASASMLHHLRLITQKTPHLEWLNLDYCARLTNMVFREMTAPLHDLRILSVASCSLVGDDAMIDLPKHNPYLQEIYLGSTQVSDQTLELLTQMKLLTHVSLKDCQQVTERGVEILMNLKTLKSLDIEDCYNVLGDHPIPVIVDDEIDDLWIDIDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-06-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NFA9</accession>
    <name>A0A1C7NFA9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_05916</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000335">
        <property type="protein sequence ID" value="OBZ86034.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NFA9"/>
    <dbReference type="InParanoid" id="A0A1C7NFA9"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ86034.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="66" mass="7548" checksum="634694C0D11EBCC3" modified="2016-11-30" version="1">MHMQQHIYQNTIVKLTVAKEVADLIMSLFSLVINVSHIKSAFLSRGNKMSIQTQPVANKIWIRLDP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NFJ6</accession>
    <name>A0A1C7NFJ6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Tonsoku-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">TONSL</name>
        <name evidence="5" type="ORF">A0J61_04405</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000215">
        <property type="protein sequence ID" value="OBZ87539.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NFJ6"/>
    <dbReference type="STRING" id="101091.A0A1C7NFJ6"/>
    <dbReference type="InParanoid" id="A0A1C7NFJ6"/>
    <dbReference type="OrthoDB" id="78308at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043596">
        <property type="term" value="C:nuclear replication fork"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000724">
        <property type="term" value="P:double-strand break repair via homologous recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031297">
        <property type="term" value="P:replication fork processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052311">
        <property type="entry name" value="MMS22L-TONSL_complex_comp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46358">
        <property type="entry name" value="TONSOKU-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46358:SF1">
        <property type="entry name" value="TONSOKU-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="954"/>
            <end position="974"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="956"/>
            <end position="974"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OBZ87539.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="974" mass="112538" checksum="03B2635B24E5BC43" modified="2016-11-30" version="1">MKNKVTYAIEYTKSNTLADGYNFYIEQYKQQLNNGKQIKAAQLIIELIDWLVDADDDNDEFLHYLDHAIKYCRKVVKSLKEVNYPFLLAKAYSCLSQAYSIQEIFDQAIHYGLESIQLLQSQQKQDEDAMDIDQPKIKLALQFGYRLLGNIYFNKGLHPKASRYSDYQHALQFYTSEREVIDTMTLTDMDSTDEDDLTKLRQSSHFNMGVMERKLPDHYTQANDDLKSALKLAQQLKDPQSEKNAWWELGNLYKTLGDHEAVKRCQASEHSVALHCGLKEDVIICFEERIKYHLYLGEFNACMKLYKKLLDYVDEDAKEACRSFLKMVKQVKALREELDRLIDKGDLNAQIATKFLTYIRLLNYYELYRVLIQTIDTSFIAITNTRDFSPLIYAQILHIKTEALWHLNESTKEVYLQASNEAYDYVEASLSESPLNQYMLMIDIFQLRVQIYEYFELDFQKTATEKVLADAIKQEKLLRYKLENNLVGVNHLYSRITPSLNQLSKKKIQVNIMTKPPVEFSMVYDHAPETVRFLMNDIASQCWNTFGFEPNISHVRTLDHDILPEDLVNNVIVEDDQHLEVHIHGIVKKTPLELYLNASRRLEIAPIKAIEYAMEMQNVTDISFMGLNIKANHQFDIVQQILEHSTALYRLNLSSNSLVNEDLEKLLKIVNPSVGEVRLSNNQLTTECLDTLTKLRVAILDLSHNPIDATLFVRLPQFLEKVPVLKRLELENTDIGRIKKDVCHAIQTKSSVNMSSSLTLDISNNHFEQDMLSKLTELWLQFNRIEGLELSSITSDFGWNNFDLLSELSSLSKLSFKYSVKTTFGYCHFKEFFMMKKTINELDLTGCGLDLEDMVMFGYSLSYIDRLNRLMLNSNPNIGDAGIKYLDAAIEKSKIISISLSHCGLTSESSQLIIRWTRYLKMLDITHNPIFDQDTLPSNSTAVMRLDPIKPAPTIRTPSMSFQSLSDLPNSPFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NFP6</accession>
    <name>A0A1C7NFP6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Cyclase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_04159</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the Cyclase 1 superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000197">
        <property type="protein sequence ID" value="OBZ87790.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NFP6"/>
    <dbReference type="STRING" id="101091.A0A1C7NFP6"/>
    <dbReference type="InParanoid" id="A0A1C7NFP6"/>
    <dbReference type="OrthoDB" id="5396at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004061">
        <property type="term" value="F:arylformamidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019441">
        <property type="term" value="P:L-tryptophan catabolic process to kynurenine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.30.50">
        <property type="entry name" value="Putative cyclase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007325">
        <property type="entry name" value="KFase/CYL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037175">
        <property type="entry name" value="KFase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34861">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34861:SF11">
        <property type="entry name" value="CYCLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04199">
        <property type="entry name" value="Cyclase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102198">
        <property type="entry name" value="Putative cyclase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ87790.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="318" mass="36071" checksum="5BC1455C28B4A676" modified="2016-11-30" version="1">MTIPTYDQLPIHPKHPKGTAWGVWGEDDNIGTANLLTPERVVNAAQYIKTGKRFPLNWGLEHPRVSLFGRQKFKHNLIEKMNGLHFDDSLDGFNLQTSSQWDGLRHFSFVPSRQFYNGVKVDQIRLNTPLSDDRLGMHHMAQKGLAGRAVLLDFHRWAAQHRPDFDPFQRHEITVEELEQVATHQQVQFELGDILLIRTGWTARYEQGGPEVEALAGDHWPLCAGIQAGEKTYRWIWDHQFSAIATDAIPVEALPFDVEDCCHSVLNGGFGMMLGEMFYLEDLAQDSAEDKVYAYFFTSAPLNLKNGIASPPNAMCIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NFS0</accession>
    <name>A0A1C7NFS0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_03995</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000186">
        <property type="protein sequence ID" value="OBZ87947.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NFS0"/>
    <dbReference type="InParanoid" id="A0A1C7NFS0"/>
    <dbReference type="OrthoDB" id="2277003at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="89"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="157"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="299"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="397"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="95"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="115"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="172"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="214"/>
            <end position="224"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ87947.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="441" mass="49984" checksum="AADA0C3740E2665B" modified="2016-11-30" version="1">MPNESPTRSYISQKKKSIDRSRYSDQFIFSDIKQRKFRWSSCFSFVSKLKKPKSTTEQQIRVAQSYEDIATSDRLDTITKVKSEKSLWPIQSLPLPQPQLQPPSSLSPPPRQTKSKRESVSYKEETPLPIEPKPRVIPRAIKTSSMLRLSLDAEALSSAESLENEGHPHRLSTASSNFTVSQPAPFRTGTLGSCSSSSSQSNHQYTFTSLPPNTAIPPLPPIPLESPRLDTPLEDKKLALKDRRRRRSPLLAPNADQLTLALKDLKEEKKEDEIQATNVVSLQPIAQVQELDQHFQTRRSAVGREKAQYDAVVSRSTSLHRRQLSHEDQKRPLQSTNHYRTSLRARSPSFSESAKPQEENEERQLDMICENQPLSTSGPTPPNQSKPFFARHHLTVTPETPPYHKHMAPSLISAPSTPNSMDSFDQDYDYLHHKKPSFSFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NHF1</accession>
    <name>A0A1C7NHF1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Vacuolar amino acid transporter 6</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">AVT6</name>
        <name evidence="11" type="ORF">A0J61_03768</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Vacuole membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the amino acid/polyamine transporter 2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000169">
        <property type="protein sequence ID" value="OBZ88179.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NHF1"/>
    <dbReference type="FunCoup" id="A0A1C7NHF1">
        <property type="interactions" value="329"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NHF1"/>
    <dbReference type="InParanoid" id="A0A1C7NHF1"/>
    <dbReference type="OrthoDB" id="438545at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000329">
        <property type="term" value="C:fungal-type vacuole membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061459">
        <property type="term" value="F:L-arginine transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005313">
        <property type="term" value="F:L-glutamate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005290">
        <property type="term" value="F:L-histidine transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015189">
        <property type="term" value="F:L-lysine transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015194">
        <property type="term" value="F:L-serine transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005302">
        <property type="term" value="F:L-tyrosine transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013057">
        <property type="entry name" value="AA_transpt_TM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22950">
        <property type="entry name" value="AMINO ACID TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22950:SF678">
        <property type="entry name" value="VACUOLAR AMINO ACID TRANSPORTER 5-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01490">
        <property type="entry name" value="Aa_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0029">Amino-acid transport</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <keyword evidence="4" id="KW-0926">Vacuole</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="74"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="99"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="187"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="215"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="253"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="286"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="328"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="379"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="403"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="439"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="domain" description="Amino acid transporter transmembrane" evidence="10">
        <location>
            <begin position="64"/>
            <end position="457"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008066"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022554"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF01490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="OBZ88179.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="463" mass="51164" checksum="1D372ECDD81507EA" modified="2016-11-30" version="1">MKNYSTIVENDTAASSISSVPTSSVFSGIGGALLDEQRPLLTNETEDSSIYNSSLCIEEPIATKISASINLSNTILGTGMLAMPAALASVGLIPGIIMIIYAGSTSCFGLYFLARCAERVGGRNASFSSLSKLTWPKLGIFFDTAIAIKCFGVAVSYLIILGDLMPQVILSFFHGAKDVELLMDRKFWISLSMITAVGPLSCLRKLDSLKYTSLIALFAVVYLVAIVVYHYFSPSYPLPPPEAIEYFRFSTKVFGQLPVFIFAFTCHQNIFSVYNELRHNDEKSIVKVITTSIGSAAFIYELVAVLGYLSFGKDVLGNIILEYPQTHFVAFGRLAIVILVIFSYPLQTHPCRASIDKILDTIQHKPFPTLETNSFDRRYWLVTTSIVVLSYLVAISISQLDIVLSFVGSTGSTAISFILPGLFYFKIYSADGYHWKRMLALFLVCYGFMVMTICLTFNIKRLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NHL3</accession>
    <name>A0A1C7NHL3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">WRKY domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">A0J61_03354</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000142">
        <property type="protein sequence ID" value="OBZ88597.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NHL3"/>
    <dbReference type="InParanoid" id="A0A1C7NHL3"/>
    <dbReference type="OrthoDB" id="2362414at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.25.80">
        <property type="entry name" value="WRKY domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003657">
        <property type="entry name" value="WRKY_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036576">
        <property type="entry name" value="WRKY_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03106">
        <property type="entry name" value="WRKY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00774">
        <property type="entry name" value="WRKY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF118290">
        <property type="entry name" value="WRKY DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50811">
        <property type="entry name" value="WRKY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="WRKY" evidence="7">
        <location>
            <begin position="216"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50811"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OBZ88597.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="283" mass="32536" checksum="343E3308E3685E97" modified="2016-11-30" version="1">MLTSHPLFYRKKDSIDSYPPSPPTSSESPTMIKSNSTLLAHAWYPPQPASPPTSAIESAQFLNLERVVQAYGDQPELLELILSSKVEEDRRRAEEAKLRRKEIDYVLHKQQSKKEESPFSMPKRSSLPRIETTKRKNSLEMLLSPSPPRSNLKLPKIQYTLPQPHVFQKPHASMEKLPPMAAGSAHSDLDLPAQKRRRREMQAITTIIETREFPYNDDYLWKNNGNTVHKKSGFKSIYYKCTNSIKGCPVNKTVTFKDNGEHLIKYRGQHLPECNRIKRISDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NHX6</accession>
    <name>A0A1C7NHX6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_03345</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000142">
        <property type="protein sequence ID" value="OBZ88608.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NHX6"/>
    <dbReference type="STRING" id="101091.A0A1C7NHX6"/>
    <dbReference type="InParanoid" id="A0A1C7NHX6"/>
    <dbReference type="OrthoDB" id="2273669at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="32"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="76"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="448"/>
            <end position="517"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="84"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="104"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="116"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="172"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="207"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="250"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="261"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="308"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="323"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="344"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="453"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="493"/>
            <end position="511"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ88608.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="517" mass="57344" checksum="C1B01FE1B2A05865" modified="2016-11-30" version="1">MTSSHTRLLMSDSEEEYGPLAAAWGDQAPKTVQPDWNSLLDPSVKTGPNDVGSGNLHRKGKNYKPIDEEYILAHRKNQQVPKKKMQEAIRKTEEALGLPESTRLSKKKPGNHKKYSTPSQTSPVSLQKTTSLPKRSKTVELATIRSPPINDEVGSKWSQSTLVDTPFWEQKNQSDSEKKNDMAHPNWTSTALPTPSSPPPMTKTDTVTHSKTQSLPASKKSPRKTGHGWDFLDEITETKPTDDETVTTNTKDERREKNKGQIWSTSTADAQDSGWNTPGENNWSTDSNWNTPSLGKNANTKNGWDVASVSSDSNSIPSDRPSWLNTIPNQDNSSNHHQRRDSNNGRTSRFSNPSKQRYSDYSTPDLPKPANYQGNRRVFIPTETAPPPPPKNSLLVTVNVELSESVKVPVPIRELDEPSKLAQEFGEKYKVQTPSVIAALTKLFSSQKELAAKKKQQKLQRRVHNHTTHSPVSSAGHHPSPQPQPQPASFSSYTSNRFANTTSPPTESASPLESALK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NIJ6</accession>
    <name>A0A1C7NIJ6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Tyrosine aminotransferase</fullName>
            <ecNumber evidence="5">2.6.1.5</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12">L-tyrosine:2-oxoglutarate aminotransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="17" type="primary">Tat</name>
        <name evidence="17" type="ORF">A0J61_03335</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>L-tyrosine + 2-oxoglutarate = 3-(4-hydroxyphenyl)pyruvate + L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:15093"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:36242"/>
            <dbReference type="ChEBI" id="CHEBI:58315"/>
            <dbReference type="EC" id="2.6.1.5"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 14 15">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Amino-acid degradation; L-phenylalanine degradation; acetoacetate and fumarate from L-phenylalanine: step 2/6.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 14">Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.6.1.5" evidence="5"/>
    <dbReference type="EMBL" id="LUGH01000141">
        <property type="protein sequence ID" value="OBZ88619.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NIJ6"/>
    <dbReference type="STRING" id="101091.A0A1C7NIJ6"/>
    <dbReference type="InParanoid" id="A0A1C7NIJ6"/>
    <dbReference type="OrthoDB" id="7042322at2759"/>
    <dbReference type="UniPathway" id="UPA00139">
        <property type="reaction ID" value="UER00338"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004838">
        <property type="term" value="F:L-tyrosine-2-oxoglutarate transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006559">
        <property type="term" value="P:L-phenylalanine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006572">
        <property type="term" value="P:L-tyrosine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00609">
        <property type="entry name" value="AAT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.640.10:FF:000048">
        <property type="entry name" value="tyrosine aminotransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004839">
        <property type="entry name" value="Aminotransferase_I/II_large"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004838">
        <property type="entry name" value="NHTrfase_class1_PyrdxlP-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005958">
        <property type="entry name" value="TyrNic_aminoTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005957">
        <property type="entry name" value="Tyrosine_aminoTrfase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01264">
        <property type="entry name" value="tyr_amTase_E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01265">
        <property type="entry name" value="tyr_nico_aTase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45744">
        <property type="entry name" value="TYROSINE AMINOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45744:SF2">
        <property type="entry name" value="TYROSINE AMINOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00155">
        <property type="entry name" value="Aminotran_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000517">
        <property type="entry name" value="Tyr_transaminase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00753">
        <property type="entry name" value="ACCSYNTHASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00105">
        <property type="entry name" value="AA_TRANSFER_CLASS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 17" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="11" id="KW-0585">Phenylalanine catabolism</keyword>
    <keyword evidence="10 14" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 17" id="KW-0808">Transferase</keyword>
    <keyword evidence="9" id="KW-0828">Tyrosine catabolism</keyword>
    <feature type="domain" description="Aminotransferase class I/classII large" evidence="16">
        <location>
            <begin position="39"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="15">
        <location>
            <position position="247"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012749"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00015959"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023232"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00031696"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00047798"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PIRNR" id="PIRNR000517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PIRSR" id="PIRSR000517-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF00155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="OBZ88619.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="409" mass="45302" checksum="121A49F227FA6840" modified="2016-11-30" version="1">MSSSRTSWNIKASRIANQAHNPIRAIVDKLKLNPDLTKPLISLSIGDPTIFGNFNVDTSINNAVIKQIESFRSNGYPPADGYLAARNAVAQAHSVPAAPLTADDVILTNGCSGALEMCFTALCNEGQNILLPRPGFSLYPSLAALKFVEPRFYDLLPEQSWEADLKQMESLIDEKTAAILINNPSNPCGSVFSREHLLDILALAEKHHVPIIADEIYCDLVFEGNTFFPMATLTSTVPILSVGGLAKKWLVPGWRIGWIFIHDRNKVFAEIHNALHQLAQTILGPNSLIQAALPDILEKTPAAFFESTIKQLEENVKLSMDKVSRIDGLVPVNPQGAMYMMVGIAVEKFKDIESDVDFCAKLLNEENVVCLPGACFNYPNFFRIVVTPTYDRLEEAYKRLDDFCARHKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NIV6</accession>
    <name>A0A1C7NIV6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Ovarian cancer-associated gene 2 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">ovca2_2</name>
        <name evidence="4" type="ORF">A0J61_03208</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000134">
        <property type="protein sequence ID" value="OBZ88749.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NIV6"/>
    <dbReference type="FunCoup" id="A0A1C7NIV6">
        <property type="interactions" value="193"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NIV6"/>
    <dbReference type="InParanoid" id="A0A1C7NIV6"/>
    <dbReference type="OrthoDB" id="414698at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1820:FF:000073">
        <property type="entry name" value="esterase OVCA2 isoform X6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005645">
        <property type="entry name" value="FSH-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050593">
        <property type="entry name" value="LovG"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48070">
        <property type="entry name" value="ESTERASE OVCA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48070:SF6">
        <property type="entry name" value="ESTERASE OVCA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03959">
        <property type="entry name" value="FSH1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Serine hydrolase" evidence="3">
        <location>
            <begin position="5"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="58"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="69"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF03959"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OBZ88749.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="238" mass="26771" checksum="A6D1CC9522A30900" modified="2016-11-30" version="1">MTNTQKLRILCLHGMVQNSTVFRKKTAVIRKKLDKMADMVYVTAPHLVTDPRYTSEAHRAAAADENAPEEEKPFGWWQPRRDPLPEDGYFEGFRESIEHIKEILIREGPFDGIFGFSQGACLAAVLLVMLENRETMPLFGPDFKHPNFKFAIVAAGFISSQQKATEHIWAHKIKAPVLHMIGEEDTLITPELQQTLVDQCLEPTIIRHTGGHVVPSNAASRNETVAFVSKFCQLDSSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NJA1</accession>
    <name>A0A1C7NJA1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">SUR7 family protein pun1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">A0J61_04560</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000226">
        <property type="protein sequence ID" value="OBZ87384.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NJA1"/>
    <dbReference type="STRING" id="101091.A0A1C7NJA1"/>
    <dbReference type="InParanoid" id="A0A1C7NJA1"/>
    <dbReference type="OrthoDB" id="2327445at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032153">
        <property type="term" value="C:cell division site"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035838">
        <property type="term" value="C:growing cell tip"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.140.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051380">
        <property type="entry name" value="pH-response_reg_palI/RIM9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009571">
        <property type="entry name" value="SUR7/Rim9-like_fungi"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28013">
        <property type="entry name" value="PROTEIN DCV1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28013:SF3">
        <property type="entry name" value="PROTEIN DCV1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06687">
        <property type="entry name" value="SUR7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="94"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="126"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="171"/>
            <end position="195"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OBZ87384.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="208" mass="22878" checksum="9770EC370F6A9D75" modified="2016-11-30" version="1">MSFFGFIATFFTFAALVLQVFTMIGSTYNQPFLRSLYFAKVNEGREFLTFGLWSYCSGTGDSVSSCSHPTPAFDWSTVSTVSQYLQINHIDKVFLANFILYWIALGFTFIALVITIMSSFRRGPDFLASLMTFVAFVVQLVVFVIILVIAVKGVNAAKDAGSSVSGSLGPSTWMTLGAFVALLISSISYCFACICGPGRVRSEEKYDY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NJR9</accession>
    <name>A0A1C7NJR9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_02649</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000102">
        <property type="protein sequence ID" value="OBZ89315.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NJR9"/>
    <dbReference type="InParanoid" id="A0A1C7NJR9"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ89315.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="76" mass="8872" checksum="5EF830611EDD59E1" modified="2016-11-30" version="1">MENCAIPGEIYKLEERVWVNDCVTFDKHTFVQFRITEEDGFFNIVFDSKLQLLQSAALFKSGWVKSMLNLRVSPLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NJY5</accession>
    <name>A0A1C7NJY5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_02493</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000095">
        <property type="protein sequence ID" value="OBZ89451.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NJY5"/>
    <dbReference type="STRING" id="101091.A0A1C7NJY5"/>
    <dbReference type="InParanoid" id="A0A1C7NJY5"/>
    <dbReference type="OrthoDB" id="5585416at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="361"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="35"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="361"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="386"/>
            <end position="401"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ89451.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="492" mass="55056" checksum="5EFB2BCDAB3BCF18" modified="2016-11-30" version="1">MAAFTQELEPCLARLGTTPEDKPLFVKEVYAIDDIESLRQLVIRKERERQSIANDLEVAARIGLVISETNEAIQIKLEQLERENKLFQDELALRANNTRQEVPPEEPEGMTDEEERLYLTRELEQARRELTKFRKEMDGLSAQLNDMASEMVDSRQKVAVYAKRLAEVEQKLTATREVNTNLQSLLDKALTSQKQSSTNTSHLVKNIQIDLARVISENEQLRARIAELENQQVECEEKLAAMVIQAQEYAARLEQAQDTIHSLSEPKLQDEEDILSMHHGGYNTYSVSSHEGGKESEITKGPVFSAEFRQEMQKEIERNLNLRNEIRHRIITADTTTTTFTDKKKSQEGLKYLVSSERESGGLASLSTSTSTSTSSSVLSAKKESNSLSPQKPSEPTQEQKASPLLMPGETGKGPVLRPASFLTGFGGFNDSGLGIAGGMASSNFITRGIPPRTFASNRNNNEPSISTRFFQRLASRLDEYDKRMSSSSSTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NKF0</accession>
    <name>A0A1C7NKF0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_02965</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000120">
        <property type="protein sequence ID" value="OBZ88976.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NKF0"/>
    <dbReference type="InParanoid" id="A0A1C7NKF0"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008889748" evidence="1">
        <location>
            <begin position="22"/>
            <end position="126"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ88976.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="126" mass="14175" checksum="936A07F33C631C2F" modified="2016-11-30" version="1">MMKSFTSFVLATMALLSVVSADIWSLNLYCYRDAQIVLWHSNELGSQTIIWNRDNLKGGNELCSSDQVICVKDAAVNMKSCEEVTFDFKVQYANIWSNNVTAVLHGNLSDVGYTSKTYNFNPSFQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NKP9</accession>
    <name>A0A1C7NKP9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">CsbD-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">A0J61_02259</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UPF0337 (CsbD) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000082">
        <property type="protein sequence ID" value="OBZ89702.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NKP9"/>
    <dbReference type="STRING" id="101091.A0A1C7NKP9"/>
    <dbReference type="InParanoid" id="A0A1C7NKP9"/>
    <dbReference type="OrthoDB" id="9999611at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008462">
        <property type="entry name" value="CsbD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036629">
        <property type="entry name" value="YjbJ_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40460">
        <property type="entry name" value="CHROMOSOME 1, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40460:SF1">
        <property type="entry name" value="CSBD-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05532">
        <property type="entry name" value="CsbD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69047">
        <property type="entry name" value="Hypothetical protein YjbJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CsbD-like" evidence="3">
        <location>
            <begin position="6"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="72"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="33"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="73"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="88"/>
            <end position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009129"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF05532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OBZ89702.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="98" mass="10161" checksum="4B08B0CA4EA9BEDA" modified="2016-11-30" version="1">MNSPSRTDAKKDQFVGSMKQNVGSALGNESMESKGQAQNTAGHGQETAANVSDYVKGTMDQVAGAVKGAYNSLAGNTGAETGNKMQQKKGEAQKEFSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NKX9</accession>
    <name>A0A1C7NKX9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">A0J61_02163</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000078">
        <property type="protein sequence ID" value="OBZ89782.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NKX9"/>
    <dbReference type="InParanoid" id="A0A1C7NKX9"/>
    <dbReference type="OrthoDB" id="2284457at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008889757" evidence="3">
        <location>
            <begin position="19"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="243"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="60"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="159"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="65"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="99"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="160"/>
            <end position="180"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OBZ89782.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="304" mass="35430" checksum="D1F068566039D234" modified="2016-11-30" version="1">MKPFILFCLFLIVTAVFAQQQKEEVANQNLANTDDSSLFRGVENAIDESTEEDDAYRILKSLQDVTDEGEEDSDMDDDNDEADSDLSEQDLIDMIHEADNDDNDDNDDEDDDEDEDDEDFVSSFPEFQNEETTEFFKNLPQQSTNKGHMQDEIEQKIENVDQEEEDDQANEPVEEAEEDEVEEQIKQEEENIEMDHAAAPFEGSQQFIPWKRPDHIIKTDNTDFYQDINFRESPETTVKSSRFKLWHFLCIIVILMIVYYRQARKTTNNMVELSNAGPSLSWPNEKDFLPSHSYNNNNKHFKFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NKZ9</accession>
    <name>A0A1C7NKZ9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_02133</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000077">
        <property type="protein sequence ID" value="OBZ89801.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NKZ9"/>
    <dbReference type="STRING" id="101091.A0A1C7NKZ9"/>
    <dbReference type="InParanoid" id="A0A1C7NKZ9"/>
    <dbReference type="OrthoDB" id="2288643at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="71"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="79"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="189"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ89801.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="189" mass="21242" checksum="7E9A65C8C369D76D" modified="2016-11-30" version="1" fragment="single">MSRSGDRSRCWQTGQDSKHETIEQFIDKFNTLRIKSGVQDSHVLVNYFLEALPNELVERFNITLESVSTEKKRPAHVQYETSSGSKRSSSLPNTQVNRDQGSSSDHKLVRFPRPTSGFAVSEKKPKTGMFCAFHRVTTHNTEECQARKRGDVPKNKNNCRRCGSPGWTPAHRCGSAVCSGPSDKDITVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NL12</accession>
    <name>A0A1C7NL12_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Endothelin-converting enzyme 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">Ece1</name>
        <name evidence="10" type="ORF">A0J61_02134</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peptidase M13 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000077">
        <property type="protein sequence ID" value="OBZ89812.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NL12"/>
    <dbReference type="STRING" id="101091.A0A1C7NL12"/>
    <dbReference type="InParanoid" id="A0A1C7NL12"/>
    <dbReference type="OrthoDB" id="6475849at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016485">
        <property type="term" value="P:protein processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd08662">
        <property type="entry name" value="M13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.390.10">
        <property type="entry name" value="Collagenase (Catalytic Domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1380.10">
        <property type="entry name" value="Neutral endopeptidase , domain2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024079">
        <property type="entry name" value="MetalloPept_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000718">
        <property type="entry name" value="Peptidase_M13"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018497">
        <property type="entry name" value="Peptidase_M13_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042089">
        <property type="entry name" value="Peptidase_M13_dom_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008753">
        <property type="entry name" value="Peptidase_M13_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11733:SF167">
        <property type="entry name" value="FI17812P1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11733">
        <property type="entry name" value="ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01431">
        <property type="entry name" value="Peptidase_M13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05649">
        <property type="entry name" value="Peptidase_M13_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00786">
        <property type="entry name" value="NEPRILYSIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55486">
        <property type="entry name" value="Metalloproteases ('zincins'), catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51885">
        <property type="entry name" value="NEPRILYSIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Peptidase M13 N-terminal" evidence="9">
        <location>
            <begin position="46"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M13 C-terminal" evidence="8">
        <location>
            <begin position="549"/>
            <end position="760"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01431"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF05649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OBZ89812.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="764" mass="86346" checksum="13316838AAA64D3F" modified="2016-11-30" version="1">MIGSLLPNSLSVHSSQLLARAETCTTQVCKDASKSILNDLDLNADPCSDFYQYTCGGWSKVNRIPDAESGTFAVLRNKNLDDLTHMLESNYDSLIENLKTAKVNSTDFLNSTQIAKDRENFNKIKDFYQSCINEPAIDSLGPTPIYPEIATMLKKLGYNASVADGRFSLDYAKQLTDALIHLGKEGIYPLFSSGVGPDDRTPEQNSVSIAQPSLGLPSREYYEQPEALSNYREGLTSLLTLILGEPAENDPLASVRRQKMLENNLSLLNEKDIEAMVDRFIEFETKLAKITVPNEQLQNPLDLYNPMSIAELHQKYPAIDWIKFFRHLIPDDASLPEKIILVTPRFMEALNDWVANSPTSADAISTQSMREFLTIKVIMSYIDTVDKKTREAYRKMYSKIASGTVAPPSRARTCISSTSKVFGQLLGRYFVMKNFGGEKQRKQVSEFMDNIKQSWSERLNAVDWLDSETKARALDKVKKIAHKEAYSIMAPDVRSSYSLGEYYASVTTDPSSYFNCQKSARLWNVKNEWKKFAEVVDKAEWYMTPHEVNAYYTPVFNEIVVPAGILQNPFYHSDLPQYLNYGGIGVVIGHEITHAFDNSGRLYDGDGRLNEWWTDATSKAFDSKSQCFIDQYSKFSVKGNNNTEYHVNGKMTLGENLADNGGVNAALMSMRRSLIEEPHKNMNLPQLEHLSPEQLFFINFGRAWCNNIRPEMSLQRIRNDVHSPPRTRVNAAVQNSPEFANAFKCNGQSQLMNPSNKCQICLRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NL17</accession>
    <name>A0A1C7NL17_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="10">L-ascorbate oxidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">AAO_0</name>
        <name evidence="10" type="ORF">A0J61_02139</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the multicopper oxidase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000077">
        <property type="protein sequence ID" value="OBZ89817.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NL17"/>
    <dbReference type="STRING" id="101091.A0A1C7NL17"/>
    <dbReference type="InParanoid" id="A0A1C7NL17"/>
    <dbReference type="OrthoDB" id="2121828at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005507">
        <property type="term" value="F:copper ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04206">
        <property type="entry name" value="CuRO_1_LCC_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd04205">
        <property type="entry name" value="CuRO_2_LCC_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd04207">
        <property type="entry name" value="CuRO_3_LCC_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.420">
        <property type="entry name" value="Cupredoxins - blue copper proteins"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011707">
        <property type="entry name" value="Cu-oxidase-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001117">
        <property type="entry name" value="Cu-oxidase_2nd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011706">
        <property type="entry name" value="Cu-oxidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045087">
        <property type="entry name" value="Cu-oxidase_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008972">
        <property type="entry name" value="Cupredoxin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11709:SF394">
        <property type="entry name" value="FI03373P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11709">
        <property type="entry name" value="MULTI-COPPER OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00394">
        <property type="entry name" value="Cu-oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07731">
        <property type="entry name" value="Cu-oxidase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07732">
        <property type="entry name" value="Cu-oxidase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49503">
        <property type="entry name" value="Cupredoxins"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0186">Copper</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008889762" evidence="6">
        <location>
            <begin position="21"/>
            <end position="695"/>
        </location>
    </feature>
    <feature type="domain" description="Plastocyanin-like" evidence="9">
        <location>
            <begin position="33"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="domain" description="Plastocyanin-like" evidence="7">
        <location>
            <begin position="169"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="domain" description="Plastocyanin-like" evidence="8">
        <location>
            <begin position="549"/>
            <end position="684"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="369"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="395"/>
            <end position="409"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00394"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF07731"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF07732"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OBZ89817.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="695" mass="79008" checksum="77016A94ACAA6E81" modified="2016-11-30" version="1">MFLKRRILFASLALIATTQAVLRRYELNVDEALVNPDCSTGAFSYPVVNGQFPGPTLYANKGDEVEVLVRNLSPSRNTSIHFHGIRQIGTNEYDGVPGVSQYFIEPGESFLHRFKIVEQAGTYFYHAHVGLQDDSVKGSFIVYESEKANPYDQPANLMLQAGPYEYNDDLVLQVSEWWHQNLKEREDYYMGSNFTIDLGAHSILLNGRTVHDQDQPGLSEDNCDGYAALEVEPNSVYRLRVIGATSFRVLAMAIKDHNMTLIEIDGELIEPYETSYLEIAPGQRYSVLIRTGDYAPGTTFSIGTSYIWRIRGGGITENGFGYIRYKEPSDRRVISEDYTYLFKKMEWIANSPTTNETANAGNSSVSIAQVNPQVMKKQNRASRKDFDGIEMPSEIVEDNESDSDDEDEHVVETNILRSASRGRATVNRYMPTSDDQTINTAAEKDTKVGQKPTGARNGNGGRPKRPGAPSQRQSRLYPGLPQLPNIDQPDWMYHQIVPLEPRKDWLDQTDVRTIVLNTEYHRLEDNRTRYSINNRIYQPEIEPALERYQAMDSSLRPDTNSEYNAHLDTYPIQFNEVIDLVLQNRRATFGCVLHPWHTHGHSHYVIASGTGDYDHSKDKDIRNFANPIYRDTTVAYPSLEVGPNKGCGWTKVRILADNPGFWAVHCHITTHMMQGKMIVLEEAPELIQKYRRYSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NLB8</accession>
    <name>A0A1C7NLB8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_02318</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000085">
        <property type="protein sequence ID" value="OBZ89639.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NLB8"/>
    <dbReference type="InParanoid" id="A0A1C7NLB8"/>
    <dbReference type="OrthoDB" id="2504162at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="414"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="307"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="312"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="340"/>
            <end position="350"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ89639.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="435" mass="50600" checksum="89C22E7F2D316358" modified="2016-11-30" version="1">METAEKHKPLSLQFQLFYNWEIESTSEAFHKHKARVYSAFKVELNQTPVFRLIHYEFERHFVSAGQLFKASGLTLTEGLFLFGLKPADFEVDFLITQFPYSDIWVSVDQARSMAMALGVEDELSLLLSEVLDDCFSSDNINRNEIMHNWIVPSIPTLQYSTRALLEATFDEIQLLDPLNRKIRTQISISKQAXMIMKDRTETGLVRWQVWAYDQFLQINEDEDESKGSLDRTGAVWDTLQGILTDMQNMSRGESQIKRTRVLSDNMMVGNMPLKKEYVGHSLPLQQLYIAVMAEKIFNELNRTFPKAPESLKQPKDEPHEQPRSQSSLSVPEAEKITGLSTETTNTSITSNHHHSNMLFHDRMDLLEQELYRVKKRSKKKLEDLQSYQDDMAQQLNELISWKSQSDRARKSERVWMLMLMFCVIFSTVSLRTFFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NLP3</accession>
    <name>A0A1C7NLP3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">RNA helicase</fullName>
            <ecNumber evidence="2">3.6.4.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="primary">DHH1</name>
        <name evidence="18" type="ORF">A0J61_02019</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18 19">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.13"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">P-body</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the DEAD box helicase family. DDX6/DHH1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.13" evidence="2"/>
    <dbReference type="EMBL" id="LUGH01000071">
        <property type="protein sequence ID" value="OBZ89928.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NLP3"/>
    <dbReference type="FunCoup" id="A0A1C7NLP3">
        <property type="interactions" value="873"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NLP3"/>
    <dbReference type="InParanoid" id="A0A1C7NLP3"/>
    <dbReference type="OrthoDB" id="10265785at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010494">
        <property type="term" value="C:cytoplasmic stress granule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000932">
        <property type="term" value="C:P-body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006417">
        <property type="term" value="P:regulation of translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd17940">
        <property type="entry name" value="DEADc_DDX6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18787">
        <property type="entry name" value="SF2_C_DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000114">
        <property type="entry name" value="ATP-dependent RNA helicase DDX6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000364">
        <property type="entry name" value="ATP-dependent RNA helicase DDX6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000629">
        <property type="entry name" value="RNA-helicase_DEAD-box_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014014">
        <property type="entry name" value="RNA_helicase_DEAD_Q_motif"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47960">
        <property type="entry name" value="DEAD-BOX ATP-DEPENDENT RNA HELICASE 50"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00039">
        <property type="entry name" value="DEAD_ATP_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51195">
        <property type="entry name" value="Q_MOTIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 13" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 13 18" id="KW-0347">Helicase</keyword>
    <keyword evidence="5 13" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 13" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="8" id="KW-0810">Translation regulation</keyword>
    <feature type="domain" description="DEAD-box RNA helicase Q" evidence="17">
        <location>
            <begin position="38"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="15">
        <location>
            <begin position="69"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="16">
        <location>
            <begin position="249"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="421"/>
            <end position="542"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Q motif" evidence="12">
        <location>
            <begin position="38"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="14">
        <location>
            <begin position="9"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="14">
        <location>
            <begin position="421"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="14">
        <location>
            <begin position="434"/>
            <end position="507"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="14">
        <location>
            <begin position="515"/>
            <end position="531"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="14">
        <location>
            <begin position="532"/>
            <end position="542"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022845"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00038316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00047984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU000492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS51195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="OBZ89928.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="542" mass="62179" checksum="57708193FE1E90EB" modified="2016-11-30" version="1">MASQQQLSHENDNWKKTLNLPKKDTRPQTEDVTATKGNEFEDYFLKRELLMGIFEAGFEHPSPIQEEAIPIALTGRDILARAKNGTGKTAAFVIPTLEKINNKKAKIQALLLVPTRELALQTAQVCKTLGKHLNIQVMVTTGGTTLKDDIMRLGETVHVVVGTPGRILDLASKNVADFSEANTFVMDEADKLLSPEFTPIIDQLISYFPKDRQIMLFSATFPMIVKSFKDKYLVKPYEINLMDELTLRGVTQYYAYVEEKQKVHCLNTLFSKLQINQSIIFCNSTNRVELLAKKITELGYSCFYSHAKMLQSHRNRVFHDFRNGVCRNLVCSDLLTRGIDIQAVNVVINFDFPKNAETYLHRIGRSGRFGHLGLAINLITYEDRFNLYKIERELGTEIQPIPPVIDKTLYVAPNALEDAQVQQPNRQQAIATRQQQQQREFHVQQQQQQQPNNYPQQYQQQMNGQQHYHQGNGQYQQQASLPPSQQQQPQQQHQHQQQQQQAQQHYQGNGGQRGYHNHHHHHGRGGRRNHNMQRGGHQSSRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NLP9</accession>
    <name>A0A1C7NLP9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Aspartate aminotransferase</fullName>
            <ecNumber evidence="7">2.6.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">Got1</name>
        <name evidence="9" type="ORF">A0J61_01966</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>L-aspartate + 2-oxoglutarate = oxaloacetate + L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:21824"/>
            <dbReference type="ChEBI" id="CHEBI:16452"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:29991"/>
            <dbReference type="EC" id="2.6.1.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="3 7">Homodimer.</text>
    </comment>
    <comment type="miscellaneous">
        <text evidence="7">In eukaryotes there are cytoplasmic, mitochondrial and chloroplastic isozymes.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.6.1.1" evidence="7"/>
    <dbReference type="EMBL" id="LUGH01000069">
        <property type="protein sequence ID" value="OBZ89975.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NLP9"/>
    <dbReference type="FunCoup" id="A0A1C7NLP9">
        <property type="interactions" value="473"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NLP9"/>
    <dbReference type="InParanoid" id="A0A1C7NLP9"/>
    <dbReference type="OrthoDB" id="6752799at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004069">
        <property type="term" value="F:L-aspartate:2-oxoglutarate aminotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006532">
        <property type="term" value="P:aspartate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00609">
        <property type="entry name" value="AAT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.640.10:FF:000064">
        <property type="entry name" value="Aspartate aminotransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.1150.10:FF:000001">
        <property type="entry name" value="Aspartate aminotransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004839">
        <property type="entry name" value="Aminotransferase_I/II_large"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000796">
        <property type="entry name" value="Asp_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004838">
        <property type="entry name" value="NHTrfase_class1_PyrdxlP-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006719">
        <property type="entry name" value="PRK09257.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11879">
        <property type="entry name" value="ASPARTATE AMINOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11879:SF55">
        <property type="entry name" value="GLUTAMATE OXALOACETATE TRANSAMINASE 1, ISOFORM B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00155">
        <property type="entry name" value="Aminotran_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00799">
        <property type="entry name" value="TRANSAMINASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00105">
        <property type="entry name" value="AA_TRANSFER_CLASS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7 9" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="6" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7 9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotransferase class I/classII large" evidence="8">
        <location>
            <begin position="49"/>
            <end position="417"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000480"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OBZ89975.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="424" mass="47585" checksum="10F1FF2A46B3791E" modified="2016-11-30" version="1">MPNAPSTRLNQINNHIMSNTASVFQEVPQAPPDMIFNLTAQYKADTNPNKINIGVGAFRTDELKPYVLPVVKKAEAILYNDETLDHEYQPIAGTATFTNAAAKLILGEESPAIKENRFAAVQTISGTGANHTAALFLSKFYEKSKTCYISNPTWANHRAIFSLVGFDVQDYPYWDPQTRGLDYEGLLQCMRDAPEGAIFVLHACAHNPTGVDPTREQWMGIANVMREKNLFPFFDCAYQGFASGDLDNDAWAVRYFVEQGFELFVCQSFAKNFGLYGERAGNLTMVAKSTQESQRILSQVEKLQRAEISNPPAFGARIVSIVLNDKALYQEWKENLQYMSHRIIEMRKALYHHLTELQTPGTWHHITDQIGMFSFTGLKAPQVKVLKEKYSIYLTDNGRVSMAGVSSSNVAYLAKAIDDVVRHV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NLR2</accession>
    <name>A0A1C7NLR2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Lysophospholipase</fullName>
            <ecNumber evidence="6">3.1.1.5</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">PLA2G4A</name>
        <name evidence="10" type="ORF">A0J61_01913</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>a 1-acyl-sn-glycero-3-phosphocholine + H2O = sn-glycerol 3-phosphocholine + a fatty acid + H(+)</text>
            <dbReference type="Rhea" id="RHEA:15177"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16870"/>
            <dbReference type="ChEBI" id="CHEBI:28868"/>
            <dbReference type="ChEBI" id="CHEBI:58168"/>
            <dbReference type="EC" id="3.1.1.5"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the lysophospholipase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.5" evidence="6"/>
    <dbReference type="EMBL" id="LUGH01000066">
        <property type="protein sequence ID" value="OBZ90037.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NLR2"/>
    <dbReference type="FunCoup" id="A0A1C7NLR2">
        <property type="interactions" value="277"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NLR2"/>
    <dbReference type="InParanoid" id="A0A1C7NLR2"/>
    <dbReference type="OrthoDB" id="6121437at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004622">
        <property type="term" value="F:phosphatidylcholine lysophospholipase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004623">
        <property type="term" value="F:phospholipase A2 activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046475">
        <property type="term" value="P:glycerophospholipid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1090.10">
        <property type="entry name" value="Cytosolic phospholipase A2 catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016035">
        <property type="entry name" value="Acyl_Trfase/lysoPLipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002642">
        <property type="entry name" value="LysoPLipase_cat_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10728">
        <property type="entry name" value="CYTOSOLIC PHOSPHOLIPASE A2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10728:SF40">
        <property type="entry name" value="PATATIN FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01735">
        <property type="entry name" value="PLA2_B"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00022">
        <property type="entry name" value="PLAc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52151">
        <property type="entry name" value="FabD/lysophospholipase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51210">
        <property type="entry name" value="PLA2C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 5 6" id="KW-0442">Lipid degradation</keyword>
    <keyword evidence="4 5 6" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="15"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="domain" description="PLA2c" evidence="9">
        <location>
            <begin position="138"/>
            <end position="774"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="406"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="410"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="442"/>
            <end position="457"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008780"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022963"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU362103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51210"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OBZ90037.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="774" mass="87532" checksum="9ED598055B6DAA6D" modified="2016-11-30" version="1">MNRLVDTPMSTRSKVVLLALVVPVIAGLYFTYTSEKSKSRRKSQCDDFIDSLPKKSTLLDTTPDGLLNRLFNASLTDMIPSAVEDLKAKMASLYPSFENQLETIRNMYNAFWEFLMLDEFKAIVQESLEEDTDPQLHPEIEWEATVREGQALSEEEVAFVKRRKQKIRAAFAFFIGVDEHEVEVEDIPHVGIASSGGGYRAMISCSGYLHAMYETGLLDTVLYFSGVSGSTWTMCQLYSPLTNASLDTLYSHLSSRIHTHIANLSNFLNVLNASRHNAKVLLHGIVQRYHQQNNSISLVDIFGMLLGGTLLAKKITLSPATRPTTSENYSESIEQFSATAINEEQDGSLIRPQLLKRSEIKLSRQREYFEDGSLPMPIYCAVRHEIESAGEAKATALMEQQEDELGMAHGDQDKEKKASEEEGAKIAQEKGSEEENEQTAQEEDKKGSQEEGEESEKKDLYQWFEFNPFDMGSEEINAWIPVWAFGRRFKEGKSQEGLPEQSIGVLMGMFGSAFVASLAHFYQEIRSLLPTTAIDKADEIIFRYQSSVSTIHPISPACFPNPFYKMPAVIQDKDETHEEVLRPKSIVESQQIELMDAGMDNNIPFYPLLRKGRDVDVIIAVDSSAEIQHMPYFDRAEGYAKRRGIQGWPKGAGWPKTASDRTYALGTCTVFDSSSSETIPDREDASATTTTYPDHVNPITLIYLPLIVNENYDPDFDPQQAEFTSTWNFSYTREQVEKLHGLAKHNVHDNIDTIRQVIRKTWERKRNERLGLLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NLZ0</accession>
    <name>A0A1C7NLZ0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Arrestin-like N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_02474</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000094">
        <property type="protein sequence ID" value="OBZ89466.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NLZ0"/>
    <dbReference type="InParanoid" id="A0A1C7NLZ0"/>
    <dbReference type="OrthoDB" id="2277683at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030674">
        <property type="term" value="F:protein-macromolecule adaptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031625">
        <property type="term" value="F:ubiquitin protein ligase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070086">
        <property type="term" value="P:ubiquitin-dependent endocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.640">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014752">
        <property type="entry name" value="Arrestin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011021">
        <property type="entry name" value="Arrestin-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050357">
        <property type="entry name" value="Arrestin_domain-protein"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11188">
        <property type="entry name" value="ARRESTIN DOMAIN CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11188:SF17">
        <property type="entry name" value="FI21816P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00339">
        <property type="entry name" value="Arrestin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Arrestin-like N-terminal" evidence="1">
        <location>
            <begin position="33"/>
            <end position="166"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ89466.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="479" mass="54956" checksum="62E0FD14F2C8872C" modified="2016-11-30" version="1">MTSALQLNIVSNVDTIHTFHSEDDTSLPDESYSITGVVELDLYHPIHIRQLSVQFEGQIESIFSTSDFFQDTNNTKADDEIPLNKWSTVESGKLMERLTRKAMGESSATFSILKEKVKILQGSHYLNKGKYSWPFSIVIQNVASLPPSILIPHHRIHYQLSARIKLNSIKERMKISYWQATNRMLQSNPRSDALSLSPSSAVSTDALSPSSSSPLSPESLSFSTLENANKSKRRNLLGVSMPIKICRHSYPSLYSLYQLHRIRYRGHRENHIEYEISMTKFACLQKRSFGFTCRFLPICPEAKIAKLEYYLEQIETYPIRAGDFSPKLVFSNTGSSPLLPRHRRFSRTTFEMNEYQHGSEIDLTLLLDLPQISPHIQTDMLRIHHKLRLIVRFVDEEKERNMSLSFPITLGTVPKLRSSIDSAERPLIEESDTVHVRQGLDAWLFEGQEQFTASYFEAYNKLPSYRDAIREGNPPSPFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NM61</accession>
    <name>A0A1C7NM61_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Vesicular inhibitory amino acid transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">slc32a1_6</name>
        <name evidence="10" type="ORF">A0J61_02426</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the amino acid/polyamine transporter 2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000091">
        <property type="protein sequence ID" value="OBZ89526.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NM61"/>
    <dbReference type="STRING" id="101091.A0A1C7NM61"/>
    <dbReference type="InParanoid" id="A0A1C7NM61"/>
    <dbReference type="OrthoDB" id="40134at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005774">
        <property type="term" value="C:vacuolar membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015179">
        <property type="term" value="F:L-amino acid transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1740.10">
        <property type="entry name" value="Amino acid/polyamine transporter I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013057">
        <property type="entry name" value="AA_transpt_TM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22950">
        <property type="entry name" value="AMINO ACID TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22950:SF692">
        <property type="entry name" value="TRANSMEMBRANE AMINO ACID TRANSPORTER FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01490">
        <property type="entry name" value="Aa_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0029">Amino-acid transport</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="47"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="74"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="120"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="163"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="186"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="226"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="265"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="303"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="348"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="374"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="405"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="domain" description="Amino acid transporter transmembrane" evidence="9">
        <location>
            <begin position="46"/>
            <end position="425"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008066"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OBZ89526.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="435" mass="47830" checksum="59DCCB986A996E00" modified="2016-11-30" version="1">MPQEDKVIVECKSAATDSHESALTENEFRFEDSGFIDVDRSNGYSSLVAFLNVFCVIAGTGILGLPYALRQGGFIGVLIFFLSWSMSTYAANILIRCLYADGRARLATYKDVAEAAFGRFGGWIAFFFNTWMLIGIPVLYVLLSGTNINTLCQGTSAELGLKLWIVICCALIGTPFVLAKSLKETAWMSVLSAFTILVVVIIVLIMCGIDSPNHPGAHHNAVIWEMFPISLSTISFSFGGNAVYTRVEASMKRPQDWPKVTASSLSTCAVLYLSVAIAGYIVYGDQVTNPVYFSIPSGAPQTIAIVLTTIHCLATAPIMVTSFSIDIEQMFDISVKRYGKVRECVIRILMRIIIMVVIALIACFVPHFSALMSLIGAFGNCTLVFMFPVLMYLRLTGFRNKPFYELIWCFFVVLLGVIGLIFGSIDAIRELKASY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NMA6</accession>
    <name>A0A1C7NMA6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">SAGA-associated factor 73</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">sgf73_1</name>
        <name evidence="3" type="ORF">A0J61_01732</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000058">
        <property type="protein sequence ID" value="OBZ90227.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NMA6"/>
    <dbReference type="STRING" id="101091.A0A1C7NMA6"/>
    <dbReference type="InParanoid" id="A0A1C7NMA6"/>
    <dbReference type="OrthoDB" id="21678at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000124">
        <property type="term" value="C:SAGA complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031048">
        <property type="term" value="P:regulatory ncRNA-mediated heterochromatin formation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1904802">
        <property type="term" value="P:RITS complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.1270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013243">
        <property type="entry name" value="SCA7_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037804">
        <property type="entry name" value="SGF73"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47805">
        <property type="entry name" value="SAGA-ASSOCIATED FACTOR 73"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47805:SF1">
        <property type="entry name" value="SAGA-ASSOCIATED FACTOR 73"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08313">
        <property type="entry name" value="SCA7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51505">
        <property type="entry name" value="SCA7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SCA7" evidence="2">
        <location>
            <begin position="64"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="126"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="207"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="11"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="39"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="52"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="154"/>
            <end position="166"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51505"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ90227.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="227" mass="26065" checksum="C3EDFD89BAA99487" modified="2016-11-30" version="1">MASNKKALSYDEQDMLSETFEEIDGKKRKRKEPADEEDSARNELEATEDKKKLKKDKKLKQKPTPKKKAPLDLDKQCGVLIPPNNNPCTRSLTCKIHSMGAKRSVEGRSQPFNDLLAVYQKKSIDKVQDKKGPISHNKNETLPAQPQEELMAEKEEEVDVDSDEETESVRLAIEQSRPLPLCRKQVFYVRRKRAYFRLRDVLFDTITPKHDSSNDLSQKAPLPSIPF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NME4</accession>
    <name>A0A1C7NME4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_01911</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000066">
        <property type="protein sequence ID" value="OBZ90039.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NME4"/>
    <dbReference type="InParanoid" id="A0A1C7NME4"/>
    <dbReference type="OrthoDB" id="2280717at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="105"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ90039.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="216" mass="25328" checksum="EFFD2A45450F4B41" modified="2016-11-30" version="1">MLMSSSNSVSSSDSSEPKEIKNSILLSRIPASPRLHQRQTPLTPPRPIASTSLDHLWSKQEKLETLESRLFALEDSERRFEHRLQLLEQPEEKDDDYMQLYITLLDQYNTLKADYKQKEKGYQQQIDQLTASLELERSKRKEEKEEAEEEAYYREEDGYLMFDSTSISGEITHYRVKIPDIHPSPHFQSVVHFQSPHLHMTLSKGLNPNAPEWKRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NMG6</accession>
    <name>A0A1C7NMG6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">AP complex subunit sigma</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">AP4S1</name>
        <name evidence="8" type="ORF">A0J61_01885</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the adaptor complexes small subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000065">
        <property type="protein sequence ID" value="OBZ90069.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NMG6"/>
    <dbReference type="STRING" id="101091.A0A1C7NMG6"/>
    <dbReference type="InParanoid" id="A0A1C7NMG6"/>
    <dbReference type="OrthoDB" id="371463at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016635">
        <property type="entry name" value="AP_complex_ssu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022775">
        <property type="entry name" value="AP_mu_sigma_su"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011012">
        <property type="entry name" value="Longin-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11753">
        <property type="entry name" value="ADAPTOR COMPLEXES SMALL SUBUNIT FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01217">
        <property type="entry name" value="Clat_adaptor_s"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF015588">
        <property type="entry name" value="AP_complex_sigma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64356">
        <property type="entry name" value="SNARE-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0813">Transport</keyword>
    <feature type="domain" description="AP complex mu/sigma subunit" evidence="7">
        <location>
            <begin position="1"/>
            <end position="137"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004308"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006972"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRNR" id="PIRNR015588"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OBZ90069.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="141" mass="16693" checksum="4EE999B426502669" modified="2016-11-30" version="1">MIRFLLVVNKSCHTRFSRYYQEIDKDHTGFELEVARQCITRQPNQALFTFIYDHKIVYRIYASLCFIIGCDSEDNEFAMLELIQLCVECLDQSFEKVTELDFVFSLEKIHMIMDEIIVKGLVTETNQQRVLEAMHALIRDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NMV3</accession>
    <name>A0A1C7NMV3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Mitochondrial import inner membrane translocase subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">tim13</name>
        <name evidence="14" type="ORF">A0J61_01473</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space.</text>
    </comment>
    <comment type="subunit">
        <text evidence="12">Heterohexamer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 12">Mitochondrion inner membrane</location>
            <topology evidence="1 12">Peripheral membrane protein</topology>
            <orientation evidence="1 12">Intermembrane side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="12">The twin CX3C motif contains 4 conserved Cys residues that form 2 disulfide bonds in the mitochondrial intermembrane space.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 12">Belongs to the small Tim family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000047">
        <property type="protein sequence ID" value="OBZ90471.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NMV3"/>
    <dbReference type="FunCoup" id="A0A1C7NMV3">
        <property type="interactions" value="357"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NMV3"/>
    <dbReference type="InParanoid" id="A0A1C7NMV3"/>
    <dbReference type="OrthoDB" id="7813104at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042719">
        <property type="term" value="C:mitochondrial intermembrane space chaperone complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140318">
        <property type="term" value="F:protein transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045039">
        <property type="term" value="P:protein insertion into mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.810:FF:000001">
        <property type="entry name" value="mitochondrial import inner membrane translocase subunit TIM13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.810">
        <property type="entry name" value="Mitochondrial import inner membrane translocase subunit tim13 like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004217">
        <property type="entry name" value="Tim10-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035427">
        <property type="entry name" value="Tim10-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02953">
        <property type="entry name" value="zf-Tim10_DDP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144122">
        <property type="entry name" value="Tim10-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11 12" id="KW-0143">Chaperone</keyword>
    <keyword evidence="10 12" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9 12" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5 12" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="7 12" id="KW-0653">Protein transport</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 12" id="KW-0811">Translocation</keyword>
    <keyword evidence="3 12" id="KW-0813">Transport</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Tim10-like" evidence="13">
        <location>
            <begin position="23"/>
            <end position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006720"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU367043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF02953"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="OBZ90471.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="95" mass="10742" checksum="4C867878D08FA081" modified="2016-11-30" version="1">MSDYSSNYGLGDLSNKKQEVMDQVRSELALANAQELINKINEKCYFKCVPKPGARLESGEQACLSKCMDRYMEAWNVVSRAYVARLQRETQGGNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NMV4</accession>
    <name>A0A1C7NMV4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Dynamin-related protein DNM1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">DNM1_1</name>
        <name evidence="7" type="ORF">A0J61_01538</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000050">
        <property type="protein sequence ID" value="OBZ90415.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NMV4"/>
    <dbReference type="FunCoup" id="A0A1C7NMV4">
        <property type="interactions" value="804"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NMV4"/>
    <dbReference type="InParanoid" id="A0A1C7NMV4"/>
    <dbReference type="OrthoDB" id="5061070at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
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    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
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    </dbReference>
    <dbReference type="GO" id="GO:0005777">
        <property type="term" value="C:peroxisome"/>
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        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
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        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008017">
        <property type="term" value="F:microtubule binding"/>
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        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006897">
        <property type="term" value="P:endocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048312">
        <property type="term" value="P:intracellular distribution of mitochondria"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000266">
        <property type="term" value="P:mitochondrial fission"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016559">
        <property type="term" value="P:peroxisome fission"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd08771">
        <property type="entry name" value="DLP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:001027">
        <property type="entry name" value="dynamin-related protein 3A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1240">
        <property type="entry name" value="Dynamin, middle domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022812">
        <property type="entry name" value="Dynamin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001401">
        <property type="entry name" value="Dynamin_GTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019762">
        <property type="entry name" value="Dynamin_GTPase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045063">
        <property type="entry name" value="Dynamin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000375">
        <property type="entry name" value="Dynamin_stalk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030381">
        <property type="entry name" value="G_DYNAMIN_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003130">
        <property type="entry name" value="GED"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020850">
        <property type="entry name" value="GED_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11566">
        <property type="entry name" value="DYNAMIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11566:SF235">
        <property type="entry name" value="DYNAMIN-RELATED PROTEIN DNM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01031">
        <property type="entry name" value="Dynamin_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00350">
        <property type="entry name" value="Dynamin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02212">
        <property type="entry name" value="GED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00195">
        <property type="entry name" value="DYNAMIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00053">
        <property type="entry name" value="DYNc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00302">
        <property type="entry name" value="GED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00410">
        <property type="entry name" value="G_DYNAMIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51718">
        <property type="entry name" value="G_DYNAMIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51388">
        <property type="entry name" value="GED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Dynamin-type G" evidence="6">
        <location>
            <begin position="24"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="domain" description="GED" evidence="5">
        <location>
            <begin position="604"/>
            <end position="691"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="504"/>
            <end position="535"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51388"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51718"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OBZ90415.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="691" mass="77234" checksum="A71BAF014F2BE107" modified="2016-11-30" version="1">MPDHIIGLINKIQDALVSIGGNESLDLPQIITVGEQSSGKSSVLEHIVQRDFLPRGSGIVTRRPLVLQLITSQHGDDYAEFLHLPQQKFFDFDQVRAEIANETDRIAGTNKGISRSPIHLKIYSKNVLNLTLIDLPGLTKIPIGDQPHDIDIQIRKLVLDYVSKSNSIILAVTPANADLANSDSLKLAKQIDPAGQRTIGVLTKLDLMDAGTHALDVLTGKAFPLKLGFIGLVNRSQQDIITNKSMQEAIKSEQLFFQSHPSYRNIADQCGSLYLSKQLNNILVNHIRQKLPDLRSKLSSLIGQTQHELTQYGDPAFHGSIHQGSLILRLLTMFSNEFISSIQGTSDIPTKELSGGARIYFIFNSIFGHALDAIQPCSNLTNDDIRTAIRNSTGPRCSLFVPEAAFDLLVRPQIKLLEAPSLRCVDLAFEELSKICHTCGTKEITRFPQLHAQLVDVVSSLLHERLTPTSDYVESLIAIECAYINTDHPDFPGAAGAMAELHKRHREEEKAERKRAARQQLMHPDQPHHKTTRSMSITSIASNASSPPRDSFLNAFFNGSQHSINKPSLGLSTEERFSKMMASLSDELDNEIKVTTSERHDREVELIRYLITAYFNIVRKTIQDLVPKAIMHLLVNFTKETVQNRLVSHLYREELFANLLQEDPAIATERERCKAMLEVYKNVFSLISEAM</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NN31</accession>
    <name>A0A1C7NN31_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">alpha-1,2-Mannosidase</fullName>
            <ecNumber evidence="13">3.2.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="primary">mns1B_0</name>
        <name evidence="15" type="ORF">A0J61_01427</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>N(4)-(alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;6)]-alpha-D-Man-(1-&gt;6)]-beta-D-Man-(1-&gt;4)-beta-D-GlcNAc-(1-&gt;4)-beta-D-GlcNAc)-L-asparaginyl-[protein] (N-glucan mannose isomer 9A1,2,3B1,2,3) + 4 H2O = N(4)-(alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;6)]-alpha-D-Man-(1-&gt;6)]-beta-D-Man-(1-&gt;4)-beta-D-GlcNAc-(1-&gt;4)-beta-D-GlcNAc)-L-asparaginyl-[protein] (N-glucan mannose isomer 5A1,2) + 4 beta-D-mannose</text>
            <dbReference type="Rhea" id="RHEA:56008"/>
            <dbReference type="Rhea" id="RHEA-COMP:14356"/>
            <dbReference type="Rhea" id="RHEA-COMP:14367"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:28563"/>
            <dbReference type="ChEBI" id="CHEBI:59087"/>
            <dbReference type="ChEBI" id="CHEBI:139493"/>
            <dbReference type="EC" id="3.2.1.113"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>N(4)-(alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;6)]-alpha-D-Man-(1-&gt;6)]-beta-D-Man-(1-&gt;4)-beta-D-GlcNAc-(1-&gt;4)-beta-D-GlcNAc)-L-asparaginyl-[protein] (N-glucan mannose isomer 8A1,2,3B1,3) + 3 H2O = N(4)-(alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;6)]-alpha-D-Man-(1-&gt;6)]-beta-D-Man-(1-&gt;4)-beta-D-GlcNAc-(1-&gt;4)-beta-D-GlcNAc)-L-asparaginyl-[protein] (N-glucan mannose isomer 5A1,2) + 3 beta-D-mannose</text>
            <dbReference type="Rhea" id="RHEA:56028"/>
            <dbReference type="Rhea" id="RHEA-COMP:14358"/>
            <dbReference type="Rhea" id="RHEA-COMP:14367"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:28563"/>
            <dbReference type="ChEBI" id="CHEBI:59087"/>
            <dbReference type="ChEBI" id="CHEBI:60628"/>
            <dbReference type="EC" id="3.2.1.113"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 11">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 13">Belongs to the glycosyl hydrolase 47 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.-" evidence="13"/>
    <dbReference type="EMBL" id="LUGH01000045">
        <property type="protein sequence ID" value="OBZ90523.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NN31"/>
    <dbReference type="STRING" id="101091.A0A1C7NN31"/>
    <dbReference type="InParanoid" id="A0A1C7NN31"/>
    <dbReference type="OrthoDB" id="8118055at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004571">
        <property type="term" value="F:mannosyl-oligosaccharide 1,2-alpha-mannosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036503">
        <property type="term" value="P:ERAD pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012341">
        <property type="entry name" value="6hp_glycosidase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001382">
        <property type="entry name" value="Glyco_hydro_47"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050749">
        <property type="entry name" value="Glycosyl_Hydrolase_47"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036026">
        <property type="entry name" value="Seven-hairpin_glycosidases"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11742:SF101">
        <property type="entry name" value="MANNOSYL-OLIGOSACCHARIDE ALPHA-1,2-MANNOSIDASE 1B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11742">
        <property type="entry name" value="MANNOSYL-OLIGOSACCHARIDE ALPHA-1,2-MANNOSIDASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01532">
        <property type="entry name" value="Glyco_hydro_47"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00747">
        <property type="entry name" value="GLYHDRLASE47"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48225">
        <property type="entry name" value="Seven-hairpin glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0106">Calcium</keyword>
    <keyword evidence="6 12" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="7" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="8 13" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="5 13" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 14" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="14">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008889796" description="alpha-1,2-Mannosidase" evidence="14">
        <location>
            <begin position="20"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="484"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </ligand>
    </feature>
    <feature type="disulfide bond" evidence="12">
        <location>
            <begin position="321"/>
            <end position="354"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007658"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00047669"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00048605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR601382-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR601382-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU361193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="OBZ90523.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="498" mass="56606" checksum="2E4D4E870B5A9B18" modified="2016-11-30" version="1">MLSLNRAVACCLFALAVEAAIPSNMLNRACQPKSQRAKLIRDAYLYAYDGYKEFAFGHDELLPVSESHSDSRNGWGASIIDSLDTMLIMGLHDEYEEALGFVEELDFSTAIGNSKGFETNIRYLGGLLAAYDLKPDPILLSKAIEVAELTLVPLFVSTKTPSGRSVKVPLTYMDVNNGNSVNTNTINLAEFGSYLMEFTRLSQVSGDPKYKQLVDDLADAIFEQPSAIPGIYPMDWTVSPFRANEKSYISVGGGADSYYEYLIKNYLLDNKKKPELLKMWQTSVESMDDYMLTPTAEDPEIQFVPAVSDNKLKYYSQELSCFWPGNIVLGATQTQDPSKQNKYIKFARTFLRSCVEVWKDTKTGIAPEAWSFNPIDNRVQDKLTKLINSKHKQKRARTFSIINSIYDLRPGDKQYQDLAWNMFLNIDRYAKAKAGYSRMKDVDQIQTNLDDFQESFFFAETLKYLYLMFVDKDCISLNDFVFNTEAHPFKLPEAIKYQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-06-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NNK0</accession>
    <name>A0A1C7NNK0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_01269</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000038">
        <property type="protein sequence ID" value="OBZ90667.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NNK0"/>
    <dbReference type="InParanoid" id="A0A1C7NNK0"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ90667.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="150" mass="16857" checksum="BA4E54F46C3EB763" modified="2016-11-30" version="1">MAPELFRSAFRVIPPAYHLLRLVDRFLPLGMDDSWTLQWLLDLPLQALLQNPPASPSPPPKVFSHHLLKDLLCYDASGPALLDSRAYVRPSHPLLVRLFDGLFFLDQESASTWVLHPYILCFCPFVAPSPMVPAPSSYPLVSSYLPTLCD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NNP5</accession>
    <name>A0A1C7NNP5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_01459</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000046">
        <property type="protein sequence ID" value="OBZ90499.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NNP5"/>
    <dbReference type="InParanoid" id="A0A1C7NNP5"/>
    <dbReference type="OrthoDB" id="10641329at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="132"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="141"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="157"/>
            <end position="169"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ90499.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="177" mass="19871" checksum="FC31150E3CCF9884" modified="2016-11-30" version="1">MHKNSKLNNTNHPQMLELQIQDNYLGVKLEIPVSVTVSANKKDKELNKKDLQATLGYRNRQINAGRALFSVDKSNVSFRVKRLGFRQRELLKRLKQSPGDTLLQSFGSSKDGVVQRGPDYLDVENIPLDKSNKATLEPLPSSRSINTPSTASDWDPLSKLPSLQPLSELSETKRDSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NNZ3</accession>
    <name>A0A1C7NNZ3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Trifunctional UDP-glucose 4,6-dehydratase/UDP-4-keto-6-deoxy-D-glucose 3,5-epimerase/UDP-4-keto-L-rhamnose-reductase RHM3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">RHM3</name>
        <name evidence="5" type="ORF">A0J61_01092</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000031">
        <property type="protein sequence ID" value="OBZ90851.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NNZ3"/>
    <dbReference type="FunCoup" id="A0A1C7NNZ3">
        <property type="interactions" value="133"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NNZ3"/>
    <dbReference type="InParanoid" id="A0A1C7NNZ3"/>
    <dbReference type="OrthoDB" id="331544at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008460">
        <property type="term" value="F:dTDP-glucose 4,6-dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009225">
        <property type="term" value="P:nucleotide-sugar metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05246">
        <property type="entry name" value="dTDP_GD_SDR_e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000304">
        <property type="entry name" value="UDP-glucose 4,6-dehydratase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.25.10">
        <property type="entry name" value="UDP-galactose 4-epimerase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005888">
        <property type="entry name" value="dTDP_Gluc_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016040">
        <property type="entry name" value="NAD(P)-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43000">
        <property type="entry name" value="DTDP-D-GLUCOSE 4,6-DEHYDRATASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16363">
        <property type="entry name" value="GDP_Man_Dehyd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0456">Lyase</keyword>
    <keyword evidence="2" id="KW-0520">NAD</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD(P)-binding" evidence="4">
        <location>
            <begin position="48"/>
            <end position="350"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001911"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF16363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OBZ90851.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="388" mass="43971" checksum="EE3C8961B78D7778" modified="2016-11-30" version="1">MSPSKDIVKSDMEKHSELVKTLDEFDLVDIGERVNEIADDLSDVKNILITGGAGFIGSFLVRKLVVLYPEYQIFVIDKLDYCGSLHNLKAVEGFPNYHFIRGDITSADFISFFLKEKKIDVIFHLAAQTHVDNSFGDSFEFTKNNVMGTHVLLEAAKINKVHRFIHVSTDEVYGEVINGPDCPEDTILSPTNPYSATKAAAECLVKAYHKSFGLPVMITRSNNVYGPYQFPEKITSKFVCSLLRGKKCYIHGDGLNSRKYLYAADVADAIDIIFHKGSVGETYNIGSPLEISNLEMARRLILLFGYREDEVDNHIEFVRDRAFNDKRYAIDCSKLERLGWAPKVDFDKGLLKTIEWYRHCTDTWWGDISSALIPHPFKVIPAYNEPSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NP35</accession>
    <name>A0A1C7NP35_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">F-box/WD repeat-containing protein pof11</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">pof11_2</name>
        <name evidence="6" type="ORF">A0J61_01096</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000031">
        <property type="protein sequence ID" value="OBZ90847.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NP35"/>
    <dbReference type="InParanoid" id="A0A1C7NP35"/>
    <dbReference type="OrthoDB" id="19711at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050995">
        <property type="entry name" value="WD-F-box_domain-protein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14604:SF4">
        <property type="entry name" value="F-BOX DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14604">
        <property type="entry name" value="WD40 REPEAT PF20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12937">
        <property type="entry name" value="F-box-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00256">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="F-box" evidence="5">
        <location>
            <begin position="59"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="388"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="428"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="468"/>
            <end position="507"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="508"/>
            <end position="547"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="548"/>
            <end position="587"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="588"/>
            <end position="629"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="234"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="282"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="234"/>
            <end position="253"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OBZ90847.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="672" mass="76402" checksum="3CED9885B21DE9F4" modified="2016-11-30" version="1">MEKHDQTDEGFVEQRFEEPHFMKGWTVDQKAEFAYQLLLCMPVSKTIELVERLSPLLHRDIISALPYEIAVQILYYLDINSLAQMTRVSKRWKAQSEDQTLWKSLFYASGWKANQTSIDRYLSGENVLLTPQTTMSAMIPSTGSSSRFADTPIKRANIAINTPYEPLSSLPITRXKPXKRSTNILLDRMILGNDQPVSPNRSDFARLAADKTDIRQPSIVQLDDAHHEDIMPSASMTTSISSSSSSSNSSNDEMISDHTITSNLQHLNLNDGLQTGTSLVIRPTQVYPSRSQPLQKRRSPSSIRNHREVLSHMIVERPFLNRPPPRRHVKYDESAIFHYREQTDTRYINWKRLYRNRSLIEKRWTEGDYRSRQFPSAQYLADLILIEEAQHNSGIYCLQFNAELLVTGSRDRNLKIWDIRTGRLRHTLEGHTGSVLCLQFNDHHLISGSSDGTLILWDIQTGQKIKTFVGHGESVLNVKLLGNKIVSCSKDRTVRTWDLKKGTTIRVFRGHRAAVNAVQFKGDRIVSASGDRTIKIWNMNTGECLKTLDSHSRGIACVEYDGEYIVSGSSDQSIKVWNATTGECIHTLLGHTDLVRTLQLDSKTKTIVSGSYDGSLKIWGLEDGKLQRTLNQSSHGRILNLQFDFSKIVCCSNLGKVIMYDFTHGMDMQFLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NP67</accession>
    <name>A0A1C7NP67_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">SNF1-related protein kinase regulatory subunit gamma-like PV42b</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">PV42B</name>
        <name evidence="6" type="ORF">A0J61_01009</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000027">
        <property type="protein sequence ID" value="OBZ90933.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NP67"/>
    <dbReference type="STRING" id="101091.A0A1C7NP67"/>
    <dbReference type="InParanoid" id="A0A1C7NP67"/>
    <dbReference type="OrthoDB" id="449052at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.580.10">
        <property type="entry name" value="CBS-domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050511">
        <property type="entry name" value="AMPK_gamma/SDS23_families"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000644">
        <property type="entry name" value="CBS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046342">
        <property type="entry name" value="CBS_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13780">
        <property type="entry name" value="AMP-ACTIVATED PROTEIN KINASE, GAMMA REGULATORY SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13780:SF128">
        <property type="entry name" value="CBS DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00116">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54631">
        <property type="entry name" value="CBS-domain pair"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51371">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0129">CBS domain</keyword>
    <keyword evidence="6" id="KW-0418">Kinase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="CBS" evidence="5">
        <location>
            <begin position="38"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OBZ90933.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="317" mass="34985" checksum="CCDC422DD6E6DB37" modified="2016-11-30" version="1">MTASVLSSNTHSSNRQDTHLHQFIQSQTVGGVLNKVKPTHRELMDLPLTSTMEQAFDLLLAGDILSVPIYKLNEQGEKQYVAIVSALDLLKLLGSKVSLETVQSNSDTLLMPLCDAISITEPLSILKSSDSLVELLQLFSSAKVHRVLIQQHNGAYVLLSQMDLIRFFQASNHQLGSTILDLPASEIKSNHATARLDYKCTAAEAFLTLAANDQISALPVMDGNGDLITDISAQDVRGLNRARWDSLMKPVVMYLKSSHGDLIPPSTCHDRFNLSQVMSAFVLRKAHRLWLVDYQTGELKGVITLTDIFTTFVSHSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NPN1</accession>
    <name>A0A1C7NPN1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Mitochondrial genome maintenance protein MGM101</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">A0J61_00867</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion matrix</location>
            <location evidence="1">Mitochondrion nucleoid</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the MGM101 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000023">
        <property type="protein sequence ID" value="OBZ91085.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NPN1"/>
    <dbReference type="STRING" id="101091.A0A1C7NPN1"/>
    <dbReference type="InParanoid" id="A0A1C7NPN1"/>
    <dbReference type="OrthoDB" id="17164at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000262">
        <property type="term" value="C:mitochondrial chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036297">
        <property type="term" value="P:interstrand cross-link repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000725">
        <property type="term" value="P:recombinational repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009446">
        <property type="entry name" value="Mgm101"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31404">
        <property type="entry name" value="MITOCHONDRIAL GENOME MAINTENANCE PROTEIN MGM101"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31404:SF0">
        <property type="entry name" value="MITOCHONDRIAL GENOME MAINTENANCE PROTEIN MGM101"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06420">
        <property type="entry name" value="Mgm101p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0227">DNA damage</keyword>
    <keyword evidence="8" id="KW-0234">DNA repair</keyword>
    <keyword evidence="6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="9" id="KW-1135">Mitochondrion nucleoid</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0809">Transit peptide</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004436"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013628"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023271"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OBZ91085.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="144" mass="16759" checksum="0A477A8F69F347A2" modified="2016-11-30" version="1">MHHINLFYGLLYLPEIKYRRILNKAFGPGGWGLAPRGEHTISPKNVSREYALICRGRFVSQARGEQDFFDVSGLPTASEGCKSNALMRCCKDLGIASELWDPTFIRKFKKKYCVEVWAEHVTTKKKKKLWRKKDDVLEYPYKEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NQ26</accession>
    <name>A0A1C7NQ26_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Ras-related protein Rab-4B</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">RAB4B</name>
        <name evidence="6" type="ORF">A0J61_00741</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the small GTPase superfamily. Rab family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000018">
        <property type="protein sequence ID" value="OBZ91215.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NQ26"/>
    <dbReference type="FunCoup" id="A0A1C7NQ26">
        <property type="interactions" value="469"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NQ26"/>
    <dbReference type="InParanoid" id="A0A1C7NQ26"/>
    <dbReference type="OrthoDB" id="9989112at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007033">
        <property type="term" value="P:vacuole organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:001193">
        <property type="entry name" value="Rab family, other"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050209">
        <property type="entry name" value="Rab_GTPases_membrane_traffic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001806">
        <property type="entry name" value="Small_GTPase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47979">
        <property type="entry name" value="DRAB11-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00071">
        <property type="entry name" value="Ras"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00449">
        <property type="entry name" value="RASTRNSFRMNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00177">
        <property type="entry name" value="ARF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00175">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00176">
        <property type="entry name" value="RAN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00173">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00174">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51419">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51421">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="182"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="198"/>
            <end position="213"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OBZ91215.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="213" mass="24090" checksum="8A1873609BEF2C74" modified="2016-11-30" version="1">MLADAYDFLLKLLLVGDSGTGKSCLLHHFLENQFKKDSVNTIGMEFGTRIIHIADKSIKLQIWDTAGQERFRSLTKSYFRGAAGALVVYDICNRDTFLGVRSWLKDVRTLANPELVIILVGNKNDKSDEREVSYLEASRFAQEHEMMFLEASALSGDGVEDMFFKCARSILSKIETGQIDPERSGSGVHFGDSSLRRMTQRTRTRKKEKSCCF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NQ32</accession>
    <name>A0A1C7NQ32_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Putative 37S ribosomal protein S16, mitochondrial</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">mrps16</name>
        <name evidence="4" type="ORF">A0J61_00724</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the bacterial ribosomal protein bS16 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000018">
        <property type="protein sequence ID" value="OBZ91222.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NQ32"/>
    <dbReference type="FunCoup" id="A0A1C7NQ32">
        <property type="interactions" value="381"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NQ32"/>
    <dbReference type="InParanoid" id="A0A1C7NQ32"/>
    <dbReference type="OrthoDB" id="407221at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005763">
        <property type="term" value="C:mitochondrial small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032543">
        <property type="term" value="P:mitochondrial translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1320.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00385">
        <property type="entry name" value="Ribosomal_bS16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000307">
        <property type="entry name" value="Ribosomal_bS16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020592">
        <property type="entry name" value="Ribosomal_bS16_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023803">
        <property type="entry name" value="Ribosomal_bS16_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00002">
        <property type="entry name" value="S16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12919">
        <property type="entry name" value="30S RIBOSOMAL PROTEIN S16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12919:SF20">
        <property type="entry name" value="SMALL RIBOSOMAL SUBUNIT PROTEIN BS16M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00886">
        <property type="entry name" value="Ribosomal_S16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54565">
        <property type="entry name" value="Ribosomal protein S16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00732">
        <property type="entry name" value="RIBOSOMAL_S16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006668"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OBZ91222.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="103" mass="11759" checksum="A2574732621BB768" modified="2016-11-30" version="1">MVVRIRLARHGRRNLPFYHIVIANARTGRNSKPIEKIGTYNPIPDETGSKLINLNFDRAKYWLTVGAQPTETVEKILVNAQLMPQAPKPWMEQAAKKFKETSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NQI5</accession>
    <name>A0A1C7NQI5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">NADP-dependent alcohol dehydrogenase C 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">adhC2_3</name>
        <name evidence="7" type="ORF">A0J61_00578</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 5">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the zinc-containing alcohol dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000013">
        <property type="protein sequence ID" value="OBZ91362.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NQI5"/>
    <dbReference type="FunCoup" id="A0A1C7NQI5">
        <property type="interactions" value="328"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NQI5"/>
    <dbReference type="InParanoid" id="A0A1C7NQI5"/>
    <dbReference type="OrthoDB" id="1879366at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016616">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05283">
        <property type="entry name" value="CAD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000022">
        <property type="entry name" value="Cinnamyl alcohol dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002328">
        <property type="entry name" value="ADH_Zn_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047109">
        <property type="entry name" value="CAD-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="ER"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42683">
        <property type="entry name" value="ALDEHYDE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00059">
        <property type="entry name" value="ADH_ZINC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Enoyl reductase (ER)" evidence="6">
        <location>
            <begin position="17"/>
            <end position="348"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU361277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OBZ91362.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="350" mass="39162" checksum="9A95F8C0458DBC15" modified="2016-11-30" version="1">MSSDNTFTAYAGVAKDKPLEKMQLELREWDEDCVQIDITHCGICGSDIHTLDQGDQWGATDYPCVVGHEITGIVTRIGRNVTHVKEGDRVGIGAQSGSCHHCSHCEEGMENLCYNGHVGTYNGKYENGSKSYGGYADKWRGDRRFVFKIPDHLSNEVAATFFCAGVTTFAPLRRSGVNEDSVVGIMGLGGLGHYGVLWAKAMGAKVIGMSHSDKKRDVAKELGCDEYLVTSDPEQMKKYKKQLTHILCTGCSPDFKWSDYLSLLHGNGYFLNVNFPEWEFPPIPPLVLIFNQCFIHGSAIGSPKEIEEMLKFAEEKQVKPWIQKYPMKDVQRAVDDFRAGKPRFRFVLEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NQM8</accession>
    <name>A0A1C7NQM8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">C-type lectin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_00537</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000012">
        <property type="protein sequence ID" value="OBZ91417.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NQM8"/>
    <dbReference type="InParanoid" id="A0A1C7NQM8"/>
    <dbReference type="OrthoDB" id="2251369at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016187">
        <property type="entry name" value="CTDL_fold"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56436">
        <property type="entry name" value="C-type lectin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008889826" description="C-type lectin domain-containing protein" evidence="2">
        <location>
            <begin position="21"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="133"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="148"/>
            <end position="167"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ91417.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="228" mass="23794" checksum="81C0A64489538FD0" modified="2016-11-30" version="1">MMNRILTAALLTSMVTLSLADVGGYVCDPPGTDGYYFAKNLTYWDEANHSCGEEGILANVNNRNFEIATNLVRNCIGDNSAAWIGTWDYTAADPQVRDCLTLYVDGEGTGGGINISCGSRRYALCRRKPTRSNSPDFHTALPAPFEGGNNGGNNGGNNGGNNGGNNGGNTSIVEVTVDNTVATVSTTTTATTTTTAITATTVSSTTTTNVVSTSVVTEPTTYVIYTSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NQR2</accession>
    <name>A0A1C7NQR2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="13">ATPase 4, plasma membrane-type</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">AHA4</name>
        <name evidence="13" type="ORF">A0J61_00503</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIIA subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000011">
        <property type="protein sequence ID" value="OBZ91433.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NQR2"/>
    <dbReference type="STRING" id="101091.A0A1C7NQR2"/>
    <dbReference type="InParanoid" id="A0A1C7NQR2"/>
    <dbReference type="OrthoDB" id="116380at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006812">
        <property type="term" value="P:monoatomic cation transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="2.70.150.10:FF:000042">
        <property type="entry name" value="Plasma membrane ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1000:FF:000008">
        <property type="entry name" value="Plasma membrane ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.150.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, transmembrane domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004014">
        <property type="entry name" value="ATPase_P-typ_cation-transptr_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023298">
        <property type="entry name" value="ATPase_P-typ_TM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008250">
        <property type="entry name" value="ATPase_P-typ_transduc_dom_A_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059000">
        <property type="entry name" value="ATPase_P-type_domA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001757">
        <property type="entry name" value="P_typ_ATPase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01494">
        <property type="entry name" value="ATPase_P-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42861">
        <property type="entry name" value="CALCIUM-TRANSPORTING ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00690">
        <property type="entry name" value="Cation_ATPase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00122">
        <property type="entry name" value="E1-E2_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00702">
        <property type="entry name" value="Hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00120">
        <property type="entry name" value="HATPASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00831">
        <property type="entry name" value="Cation_ATPase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81653">
        <property type="entry name" value="Calcium ATPase, transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81665">
        <property type="entry name" value="Calcium ATPase, transmembrane domain M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-1278">Translocase</keyword>
    <keyword evidence="4 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="85"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="109"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="412"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="440"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="477"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="519"/>
            <end position="540"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="552"/>
            <end position="573"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="585"/>
            <end position="605"/>
        </location>
    </feature>
    <feature type="domain" description="Cation-transporting P-type ATPase N-terminal" evidence="12">
        <location>
            <begin position="29"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="660"/>
            <end position="695"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="668"/>
            <end position="677"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="679"/>
            <end position="695"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008804"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM00831"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="OBZ91433.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="695" mass="76242" checksum="8E41E5DB855D0544" modified="2016-11-30" version="1">MAEEQPHAKITGDFHNITVEELYDKEKYDLSTMEQQDVMQLLQTQPEGLTTAEAEKRTEKFGRNKLETKDVNPFFQFLGFMWNPLSWVMEAAAIVAIALSNGFGKPPDYPDFIGIVLLLLANATIGFLEERQAGNAVKALMASLAPECKVKRDGEWKTMEAAELVPGDIISVKLGDVIPADGRLLSAHGDVSIDQAALTGESLPVATIKALNDDVDEFARRGLRALAVAIDEIPSGEVGGEGIGFKLVGLLPIYDPPRSDTKETIDRSLALGVAVKMITGDQLAIAKETGRRLGMGDNMFLSKTLKEGPPAGSGYTDVDQMVLHADGFAGVYPEHKYEIVERLQNMGYMVAMTGDGVNDAPALSKANVGVAVADASDAARSAADIVLTAPGLSTIVEAIIGSRQIFQRMRNYSIYTCSVTIRVVVGFSILIWAFQFDFPPFMILIIAILNDGTIMTISKDRVKPSPFPDAWNLKEIFSYAIVYGLYLTASTVAFVAVALKTSFFQSKFGIQTFTDPNDYVLHSAVYLQVSTISQALIFITRSRGWFFTERPSILLVISFIIAQLVAMFISVYANWGFTSIQGTGWSIAGIVWIWNFVWFAPMDLIKFAMQRVFEPRTNNPEDAKAVASRRASQVSGTSGRLYANRTRSLRSMERPQNFANKIMGKSGKKMDPKEMRRFSSVQTSHAAQVLGGNNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NQV4</accession>
    <name>A0A1C7NQV4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Transcriptional regulatory protein dep1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">dep1</name>
        <name evidence="7" type="ORF">A0J61_02304</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000085">
        <property type="protein sequence ID" value="OBZ89644.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NQV4"/>
    <dbReference type="STRING" id="101091.A0A1C7NQV4"/>
    <dbReference type="InParanoid" id="A0A1C7NQV4"/>
    <dbReference type="OrthoDB" id="20886at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005654">
        <property type="term" value="C:nucleoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010468">
        <property type="term" value="P:regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.1500">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013907">
        <property type="entry name" value="Sds3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21964">
        <property type="entry name" value="BREAST CANCER METASTASIS-SUPPRESSOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08598">
        <property type="entry name" value="Sds3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01401">
        <property type="entry name" value="Sds3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0678">Repressor</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="15"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="46"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="66"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="80"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="145"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="175"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="244"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="266"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="310"/>
            <end position="328"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OBZ89644.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="513" mass="58599" checksum="F2C860D7DA8D1BA6" modified="2016-11-30" version="1">MMDSHVTEESNTRQGSKLSLGSSPSALSADEQLEGEGPLTPTDKLQDDEEDEEVHNEDDDDDDLSALNSILQAGSAGSLSDEEEDDEEDHDDKTTTAKAEEEDDDEQDSASPLSSVPDDFPLSRSASPELPLVEPLSQPEPSTVKNEKRETEKKPATRKRRKDSLMKTTTNTRDSIADSHDLPESKRPKLAETIETKAVDAIDHSANEEEDMMSHDETNPKNKRRRVSRSSLVEVESRTRRRQSKDGPVIKKEEDSTDTADQPMDETPKRPLADKSNLHEHQTESPKAQAIRPEDELEETDETKDKKKKKEEPIEQGHHESHDDHDYQQRHKEALDALTHIEVEFARLRDKMYQEKMSELNEEAIMIANGTHPELVTLMAEIEEKKGRRIHSAEAWRRYQHANFRQQFEGFEYQANIHFISQRNALRRQLLEQINGKRWSIEDERSKLNDPSKNGHLFPDGREMIAHKRELKEETGELQDIKEAIGFPMAPNPSGLNAHDLNEDLKLLGIHRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NSC5</accession>
    <name>A0A1C7NSC5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Beta-chimaerin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">Chn2_0</name>
        <name evidence="5" type="ORF">A0J61_01771</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000060">
        <property type="protein sequence ID" value="OBZ90184.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NSC5"/>
    <dbReference type="STRING" id="101091.A0A1C7NSC5"/>
    <dbReference type="InParanoid" id="A0A1C7NSC5"/>
    <dbReference type="OrthoDB" id="79452at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00159">
        <property type="entry name" value="RhoGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.555.10">
        <property type="entry name" value="Rho GTPase activation protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050729">
        <property type="entry name" value="Rho-GAP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008936">
        <property type="entry name" value="Rho_GTPase_activation_prot"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000198">
        <property type="entry name" value="RhoGAP_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23176:SF128">
        <property type="entry name" value="RHO GTPASE-ACTIVATING PROTEIN RGD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23176">
        <property type="entry name" value="RHO/RAC/CDC GTPASE-ACTIVATING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00620">
        <property type="entry name" value="RhoGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00324">
        <property type="entry name" value="RhoGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48350">
        <property type="entry name" value="GTPase activation domain, GAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50238">
        <property type="entry name" value="RHOGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0343">GTPase activation</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rho-GAP" evidence="4">
        <location>
            <begin position="212"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="110"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="9"/>
            <end position="43"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022468"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50238"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OBZ90184.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="395" mass="45134" checksum="7925DF2D0E510F28" modified="2016-11-30" version="1">MLAHWKTIEQFYVNRLNSLQKEIESAIQQNEKLSIARDELVQDILHLHKKSTELTMKNECLTKSITEKQELKKTHYITETRGVTLEDTPYTPPSPPPISGGNEHHVAEVTFESKSEQPPKLNPENVRQPGLFRKISLRLSTKKRRQEDHQPPLQISDPLNAPAPISSPTVDAIAPTASISEPLLHPAAVVTSSFDCSSPVTQKRKKNAIFGNDLVQQAKSENTRIPFIILNCIREVELRGLSVEGIYRKSGTLIQIKELQDAMSEQKNIMLSQYQDVSVITSVLKLYFRELPTPLISNDFICPADMQVQERVDKICSLLRLMPNECYHTLKYLMEHLRRVHQNHTINRMPSKNLAVIFGPTLMRFTAGNEEQQMRDMIDTIDFFILHSHVIFAEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7LQ28</accession>
    <name>A0A1C7LQ28_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_11920</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01002696">
        <property type="protein sequence ID" value="OBZ66117.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7LQ28"/>
    <dbReference type="STRING" id="101091.A0A1C7LQ28"/>
    <dbReference type="InParanoid" id="A0A1C7LQ28"/>
    <dbReference type="OrthoDB" id="2274210at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="163"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ66117.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="163" mass="18774" checksum="ADF5629A4101C3F8" modified="2016-11-30" version="1" fragment="single">MDYVIEEGEEFNLRNLTNLSEYNDCQAVPIELDAEDENLESRISLVIEKANKTVADKVGNQTNKSSRAKSQLQEPQKLHILELFDNKPYTTTDEVVDSLTKAFEGFTLKQSTVNSFILHECDLTIKRLQRQPKARNDPARNQARYDWVMKYDSPGMDSLRNCI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MTD9</accession>
    <name>A0A1C7MTD9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_11821</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01002537">
        <property type="protein sequence ID" value="OBZ80130.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MTD9"/>
    <dbReference type="InParanoid" id="A0A1C7MTD9"/>
    <dbReference type="OrthoDB" id="10366247at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ80130.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="138" mass="15917" checksum="04EC9B94A409E5EE" modified="2016-11-30" version="1" fragment="single">MMKEEEPQFFDLILNYRENADNNDYFEKTGNFLRVGKAGIFTCSSSDINQDIIGIIDSVEKFTVQENGKDVKSAKYTISIYRFETLNPSFSFIYLDRNPGSDSLFPGWLTTQNNNIVMRKRMTVVRGLATKSEVVQRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MU70</accession>
    <name>A0A1C7MU70_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_11568</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01002204">
        <property type="protein sequence ID" value="OBZ80383.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MU70"/>
    <dbReference type="InParanoid" id="A0A1C7MU70"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="72"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="100"/>
            <end position="122"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ80383.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="177" mass="19477" checksum="79FF4552607CCB7F" modified="2016-11-30" version="1">MKQVSDLSSAPWCLLYKIPFQNQKEALLSLRALAVQNKIPTTRCHNFWFENSLLAYLYHIKARPSRAKINPLVAAITITISTSTTTATATTITTTITTTIAIITAIITTTAIITATTVIITITIKVIFDNRSAAVAAATAITTATSGEKKKKYVGWFRGSYLIETMIDARFLEDHHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MU93</accession>
    <name>A0A1C7MU93_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_11569</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01002205">
        <property type="protein sequence ID" value="OBZ80382.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MU93"/>
    <dbReference type="STRING" id="101091.A0A1C7MU93"/>
    <dbReference type="InParanoid" id="A0A1C7MU93"/>
    <dbReference type="OrthoDB" id="2289822at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="172"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ80382.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="172" mass="19280" checksum="8AF19BCAE682A57F" modified="2016-11-30" version="1" fragment="single">MYDNKLVIKKEGVELFRNRVAILGVTGDIPGISELMMAAEHTATFGCRICKVKGHKPHGVSNKGKYYPKMGPLRTLDELKNGDLAHGMPGVPKLSTDLKTFINPHFFFGDELHMLGHGMGHMVYKLLDPKTSYWFQAANVNHYPFQVSSSFRPKNFMKKLGDWIAASKPTCP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-06-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MUG8</accession>
    <name>A0A1C7MUG8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_11491</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01002104">
        <property type="protein sequence ID" value="OBZ80460.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MUG8"/>
    <dbReference type="InParanoid" id="A0A1C7MUG8"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ80460.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="63" mass="7342" checksum="B9CADE8B2A0729B2" modified="2016-11-30" version="1" fragment="single">MSLCTKTLTFKTNAILCKDFGTADFEVGLWVAEDVDFRILFTEERRKAVAFVNQGKYMKEDHY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MV38</accession>
    <name>A0A1C7MV38_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_11249</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001828">
        <property type="protein sequence ID" value="OBZ80702.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MV38"/>
    <dbReference type="STRING" id="101091.A0A1C7MV38"/>
    <dbReference type="InParanoid" id="A0A1C7MV38"/>
    <dbReference type="OrthoDB" id="2290219at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00303">
        <property type="entry name" value="retropepsin_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.70.10">
        <property type="entry name" value="Acid Proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021109">
        <property type="entry name" value="Peptidase_aspartic_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13650">
        <property type="entry name" value="Asp_protease_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50630">
        <property type="entry name" value="Acid proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ80702.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="377" mass="40700" checksum="BA2798D03E1552BB" modified="2016-11-30" version="1">MNLYRNNRSGSSGPSRKPTLNAIDTTVTDADCDCSPSSSTSHNKATDSSSYLSSVSSQLSQNVVISSESETDSKCENKLNPQFTSLPSAVRMIGPPNEASRLPVELVSEKSSDAIHLSNLNTVVSCNLPLYHGVLTSVDGDSIDVHVLIDNGASENYIAPHVSHLIEGTRHRVQGRKVETAGGNTSPITEKVVFDLSLQGHTSSMSAFVFDTKFDIILGRSWLKEHKPKANWLDDSGKVSCCLDVGSDGTILPVQDDFRPLLDDVVAPVSLNYLISKKQAKKVIGKDGADVCLLYLLDDSDSSSTVRDNASSFWSHLPEDFPSVFLDRLPGLPSDRGVQHVIDTGDCKPITPQLMGKKSCVADCVGATLKIWANHTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MWF6</accession>
    <name>A0A1C7MWF6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">CCHC-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">A0J61_10736</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001355">
        <property type="protein sequence ID" value="OBZ81215.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MWF6"/>
    <dbReference type="STRING" id="101091.A0A1C7MWF6"/>
    <dbReference type="InParanoid" id="A0A1C7MWF6"/>
    <dbReference type="OrthoDB" id="2273366at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.60.10">
        <property type="entry name" value="Zinc finger, CCHC-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001878">
        <property type="entry name" value="Znf_CCHC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036875">
        <property type="entry name" value="Znf_CCHC_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33223">
        <property type="entry name" value="CCHC-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33223:SF6">
        <property type="entry name" value="CCHC-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00098">
        <property type="entry name" value="zf-CCHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00343">
        <property type="entry name" value="ZnF_C2HC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57756">
        <property type="entry name" value="Retrovirus zinc finger-like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50158">
        <property type="entry name" value="ZF_CCHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="CCHC-type" evidence="3">
        <location>
            <begin position="561"/>
            <end position="576"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="76"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="486"/>
            <end position="560"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="17"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="31"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="43"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="101"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="494"/>
            <end position="517"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="526"/>
            <end position="537"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OBZ81215.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="698" mass="78275" checksum="8D8D0A4C24CD2D0B" modified="2016-11-30" version="1">MVNNTISGSVPEGGDGSNSRSSTPASRRSSGAESTVNTELHATVSGSGSRITGSTRETSSISSRASVATITNYGNATAGASSQDDRIPAPPSFSGSALEAMEAHRSLSEQGDYHSERSVVIEDHLEQYHRIMNQYQDLHDYVHWRRQEMLNEITAAENSYTAVERAVVHFGPSEKQAVGDLFATYAKKIEELKARVSFFDAEIMPTRERIRDELIGGLNSLPGHVMLRIVQETQWPNESISQDLGLPYDYLLLYRGTYALPKVDVRTEEAPTTETLEKARIRELEAMVQQLSLQIKRGDTGGRLADKAATTKLIETKPEADRIDYQERRKRTRFPTFGSGTVAEAQGWVKRYELLCEFVNFTDKEKVAELSVLFIDAALSWYLNTDHSSWATVKRGFLKQFGGGTDPSKAAHNELKSLRKGRMSMKQFGPLITDLLHRAEIYRPSMQLDYFKERLNDELQMAMVYRGPKTLEEAIHVMTSVEEELQRMAQGKTAPSALPGPYAASSSGSSSTTQPLQQNYQQTRGYGDRRSGKEAYDRNQGSRKASAGGRPQPKGTESRTCFICGKRGHLAKNCRRRKQEHSQSQQMTQDEAHADGMVDIFAHLGKPIQNTQVAKELEVSTQYRFLKEFYLKNGGRQTGSSHVLNPVDTYSIRHWNHPVNYTEGNSQVHHRWNTNKSLPLYRRESKHGRYIGYGLDGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MWT7</accession>
    <name>A0A1C7MWT7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Protein SET</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">SET</name>
        <name evidence="4" type="ORF">A0J61_10670</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the nucleosome assembly protein (NAP) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001302">
        <property type="protein sequence ID" value="OBZ81282.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MWT7"/>
    <dbReference type="STRING" id="101091.A0A1C7MWT7"/>
    <dbReference type="InParanoid" id="A0A1C7MWT7"/>
    <dbReference type="OrthoDB" id="19419at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006334">
        <property type="term" value="P:nucleosome assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1120.90">
        <property type="entry name" value="Nucleosome assembly protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037231">
        <property type="entry name" value="NAP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002164">
        <property type="entry name" value="NAP_family"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11875">
        <property type="entry name" value="TESTIS-SPECIFIC Y-ENCODED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00956">
        <property type="entry name" value="NAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143113">
        <property type="entry name" value="NAP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="176"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="183"/>
            <end position="205"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003876"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OBZ81282.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="212" mass="24648" checksum="CD91B38509301390" modified="2016-11-30" version="1">MSVEDSISDDFAVLQEETIEAIQQVEAYQRKLMAPIYHKRREIAKKIPHFWSQSLGNSPLFAFEPSDNDVEALENLTELHVEYDDSKPNYRKVVATFKKNDLFKNETLTKEFSIDPEDEGSVISKTTIEYHESKDSKKRKSREDDEDDATFLEWFGNDDVRSGILITEDFFPNALDYYKGDEESGDEIDDDIELGSEDDEDDEDEHIQKKKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MX82</accession>
    <name>A0A1C7MX82_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_10528</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001217">
        <property type="protein sequence ID" value="OBZ81423.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MX82"/>
    <dbReference type="InParanoid" id="A0A1C7MX82"/>
    <dbReference type="OrthoDB" id="2273669at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ81423.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="77" mass="8867" checksum="031137E245A082CD" modified="2016-11-30" version="1">MQPPLIHHRLDSPCVNFNIELTAGVTATLAVYENDIPIEVVNRFEKEHHLVMSEVAKNKFALTVEGYLSQYRPRPMF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MXK9</accession>
    <name>A0A1C7MXK9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Protein LSM12 B</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">lsm12b</name>
        <name evidence="3" type="ORF">A0J61_10374</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001141">
        <property type="protein sequence ID" value="OBZ81577.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MXK9"/>
    <dbReference type="STRING" id="101091.A0A1C7MXK9"/>
    <dbReference type="InParanoid" id="A0A1C7MXK9"/>
    <dbReference type="OrthoDB" id="1057137at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047574">
        <property type="entry name" value="AD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039683">
        <property type="entry name" value="Lsm12-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019181">
        <property type="entry name" value="LSM12_ABD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13542">
        <property type="entry name" value="LSM12 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09793">
        <property type="entry name" value="AD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00995">
        <property type="entry name" value="AD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52001">
        <property type="entry name" value="AD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AD" evidence="2">
        <location>
            <begin position="58"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS52001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ81577.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="154" mass="17421" checksum="99E97F4B0899A223" modified="2016-11-30" version="1">MEEVATRQQKHHNNNTTHVNKKSLESMIGKMIKIKTASNEQLEEIISVHGESKKDEIYPIPLDRLKHREIETTKEFKNNIAKMGVGVTKEAQDIFNALSKTLPCRWSKDTIVVMDEILISPPYGVEDCKANATSAPLLARVKKVINKQLDRSLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MXU8</accession>
    <name>A0A1C7MXU8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Transposon Tf2-6 polyprotein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">Tf2-6_1</name>
        <name evidence="9" type="ORF">A0J61_10360</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001135">
        <property type="protein sequence ID" value="OBZ81591.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="FunCoup" id="A0A1C7MXU8">
        <property type="interactions" value="2"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7MXU8"/>
    <dbReference type="InParanoid" id="A0A1C7MXU8"/>
    <dbReference type="OrthoDB" id="2275801at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016779">
        <property type="term" value="F:nucleotidyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015074">
        <property type="term" value="P:DNA integration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00303">
        <property type="entry name" value="retropepsin_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd09274">
        <property type="entry name" value="RNase_HI_RT_Ty3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01647">
        <property type="entry name" value="RT_LTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.270:FF:000020">
        <property type="entry name" value="Transposon Tf2-6 polyprotein-like Protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.70.10">
        <property type="entry name" value="Acid Proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.10.10">
        <property type="entry name" value="HIV Type 1 Reverse Transcriptase, subunit A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043502">
        <property type="entry name" value="DNA/RNA_pol_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001584">
        <property type="entry name" value="Integrase_cat-core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021109">
        <property type="entry name" value="Peptidase_aspartic_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050951">
        <property type="entry name" value="Retrovirus_Pol_polyprotein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000477">
        <property type="entry name" value="RT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041577">
        <property type="entry name" value="RT_RNaseH_2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37984">
        <property type="entry name" value="PROTEIN CBG26694"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37984:SF5">
        <property type="entry name" value="PROTEIN NYNRIN-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13650">
        <property type="entry name" value="Asp_protease_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17919">
        <property type="entry name" value="RT_RNaseH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00078">
        <property type="entry name" value="RVT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56672">
        <property type="entry name" value="DNA/RNA polymerases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50994">
        <property type="entry name" value="INTEGRASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50878">
        <property type="entry name" value="RT_POL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="3" id="KW-0540">Nuclease</keyword>
    <keyword evidence="2" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Reverse transcriptase" evidence="7">
        <location>
            <begin position="350"/>
            <end position="529"/>
        </location>
    </feature>
    <feature type="domain" description="Integrase catalytic" evidence="8">
        <location>
            <begin position="865"/>
            <end position="1026"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="738"/>
            <end position="757"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1154"/>
            <end position="1187"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1375"/>
            <end position="1400"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1437"/>
            <end position="1512"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1164"/>
            <end position="1173"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="1437"/>
            <end position="1454"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1455"/>
            <end position="1468"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="1488"/>
            <end position="1497"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="1531"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50994"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OBZ81591.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="1531" mass="172865" checksum="4D37086173D180B1" modified="2016-11-30" version="1" fragment="single">NNESEVTASEAPVVHKEEKTTKHQYNNSTQLDSDKLTADNNVASNTHNQPITSINTAIKQSSRPTIELIPVVHDIFLDSQEANRWEQDALYLSSLNAAITSSLPLYNGTIPSLNDKPITVQILIDNGASENYISPRVAEVILGIRTSVRDREVETAGGNISAITEKMSFELGLQGHINSMSAFVFNTKFDIIIGRSWIKRHKPEAHWDNDSWTLHCCCSRTGYPSVTIIPSNDTSTNRSSHQLNYLISHLQLESILEEEGTDCYYLYLLDNENKSKTKVDDLEDTALWTRELAKDFPSVFQEKLPGLPPMRNDFSHVIETLEDVRPINRPPFGMSPAELDELKLQLNELLSLGLIRKSTSEWGAPILFVRKKNGELRMCIDYRALNKVTKRNTNPLPQIDECLDRLQGASYFTSPDLRSGYHQIRIQDSDVPKTAFNTRYGKYGFLVLPFGLSNAPPSYQTWMNQILGDYIDKFALVYLHDVCIYSRTKEDHIRHVRDIQKRFEKEGLVVNLKKCEFGKRELEFLGYRVSQKGILPSESKIKAVKQLKRPTNVQEVRQFLGLAQHYRRFCPGFSTVASPMTELTHGTGAKKRAIIWNDACEESIKKIKNMLTSPPLLKLPDMNLSYRIETDSSDYGIDAVLLQQDPSSQAWRSIAYEFKKLSKPEQAFPAQDRELIAIIHALRTWRCFIDGCIGGYTVYSDHKPLLYFQSQLKPTPRLIRWMSEYELFNPRVEYKPGKDNNAADALSRRPNLLDDNEPEQAPLEPEYLYSIWDTLSPDIRVDWPMLYINDNHHKLRSSTLHRKLEMEKDHFVVRGNQVHRKVKVDDDSTVEAKFVPFVERADLVTKYHEGFGHAGIKHSTVVENMSTVPTEQQSRKSPSRREMPKTIYGNKWLLVAVDYLINWPIARAVPVASQEAVADFIYEEIVMRFGCPTEIITDRGANFTSGLVKAYVKRLSVNHELTSAFHPRTNGKVERYNGVLKQMLRKYVNGAIHRWDDFVNAALWTSRIRVHSTTGFSPFYLTYGREPKLPGDIQQPCISLDVLNDARTKADINLRELQLLGQHRAAADFRLRAMGEREKQIWDAKIKKVKFEAGDMVMLTHEGKYGLEPRFKGPYIITKTFPDYGTFQLETVAGEPLSSLVHADRLKPALGEKPLNPWYHPTASRRDVRDHNKTLSNTPASDEREGTMSVYKDQPPISSHPAFDINNPPPDWVDPPISSIPNLSGRAVTSTPTVQLPLDPDVTVGSRDLNNSDVTIINEDPPFETHYEVQFDADMNTVTLESNTESMEVADVNQSLSENILPSVSNEPLGIDEDMRLPDADMSDNDFLSLNESEIALDERLSLPDPVDNMMIPSSPTLSTESRNDSDTQLVETISLPTNSPLPPRQVVEPSTPISVEPSTVPTGSFSFRADIPSFAPPPVLQTKATSTTAPLKFKVPLVSPKPASPASSSSRPDSAVDVRGRTSDSKGGDVGLVLAAGGDIDEELSRSKHKDKRKRFAPTIAQRNQSKRTNKNLLRSTINKLKLLPLGFSY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MY25</accession>
    <name>A0A1C7MY25_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">40S ribosomal protein S0</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">RPS0_1</name>
        <name evidence="3" type="ORF">A0J61_10211</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001074">
        <property type="protein sequence ID" value="OBZ81740.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MY25"/>
    <dbReference type="STRING" id="101091.A0A1C7MY25"/>
    <dbReference type="InParanoid" id="A0A1C7MY25"/>
    <dbReference type="OrthoDB" id="414863at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015935">
        <property type="term" value="C:small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10490">
        <property type="entry name" value="Glucose-6-phosphate isomerase like protein, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005707">
        <property type="entry name" value="Ribosomal_uS2_euk/arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023591">
        <property type="entry name" value="Ribosomal_uS2_flav_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11489">
        <property type="entry name" value="40S RIBOSOMAL PROTEIN SA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52313">
        <property type="entry name" value="Ribosomal protein S2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="1 3" id="KW-0689">Ribosomal protein</keyword>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ81740.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="80" mass="8947" checksum="EBCFFD2CB28C5316" modified="2016-11-30" version="1" fragment="single">MSRVPSVLNPTEEDIKLLLSAQCHIGTKNVNTRMTPYVHKRRADGINLINIGKTWEKLILAARVIAAIENVSLGQFHANR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MYA2</accession>
    <name>A0A1C7MYA2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_10171</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001058">
        <property type="protein sequence ID" value="OBZ81782.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MYA2"/>
    <dbReference type="STRING" id="101091.A0A1C7MYA2"/>
    <dbReference type="InParanoid" id="A0A1C7MYA2"/>
    <dbReference type="OrthoDB" id="2202398at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ81782.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="125" mass="14206" checksum="6E7D3A44745D7BC0" modified="2016-11-30" version="1">MSLGLTSSEDYLGTVIEISLVFKETCDIATSQPIIVDEKNFYASPAIHPDRALLKVDLTKLPIWEGQCLQDSLLNNLSRYGIVREMTLYLDDWSGCWFTGNGHLYLEQPNDNNKTFESLTYKIPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MZ30</accession>
    <name>A0A1C7MZ30_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">PB1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_09933</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000975">
        <property type="protein sequence ID" value="OBZ82018.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MZ30"/>
    <dbReference type="STRING" id="101091.A0A1C7MZ30"/>
    <dbReference type="InParanoid" id="A0A1C7MZ30"/>
    <dbReference type="OrthoDB" id="9450131at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000935">
        <property type="term" value="C:division septum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043332">
        <property type="term" value="C:mating projection tip"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030010">
        <property type="term" value="P:establishment of cell polarity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031106">
        <property type="term" value="P:septin ring organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05992">
        <property type="entry name" value="PB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053026">
        <property type="entry name" value="CDC42_GEF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053793">
        <property type="entry name" value="PB1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000270">
        <property type="entry name" value="PB1_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47339">
        <property type="entry name" value="CELL DIVISION CONTROL PROTEIN 24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47339:SF1">
        <property type="entry name" value="CELL DIVISION CONTROL PROTEIN 24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00564">
        <property type="entry name" value="PB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00666">
        <property type="entry name" value="PB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54277">
        <property type="entry name" value="CAD &amp; PB1 domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51745">
        <property type="entry name" value="PB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PB1" evidence="1">
        <location>
            <begin position="63"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51745"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ82018.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="144" mass="16476" checksum="9BB1CF3857540BF1" modified="2016-11-30" version="1" fragment="single">ESIDNDFYSELEEVYGSLHEMTVQDREKDRIRSRLGNNGKDDFKLQASTSTSTVGSNSSNGGRIKIKVHYTDTRILLVSTAITFDELKSRIIDKFTAPPSIRLQYKDEDNEMVLMIDDDDLFMARQVNKSTSDLEKVEIWCVNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MZ38</accession>
    <name>A0A1C7MZ38_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_09872</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000960">
        <property type="protein sequence ID" value="OBZ82077.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MZ38"/>
    <dbReference type="InParanoid" id="A0A1C7MZ38"/>
    <dbReference type="OrthoDB" id="2425129at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ82077.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="260" mass="29668" checksum="7D79191E926A03F6" modified="2016-11-30" version="1">MVDFESLDEAVRLRYPADSSPFSRHRIPVFKARVSTCSEYKDRLRIKFDSILDRFPFKTKEQRKIVQTLGNDEHWDAVDYGLLNAKFIYSSFIAMNTLFSQPISLEANESMFNHMAIWPILSLAIDDRTSFLPGEIELSASSKNYNADALIKYGEVEVCVLETSGRYKLEDNARFGYDHVKGAFALLSMIKAIYKKYRFATKETAVELRVHFVHARGTKMHLWSLEAPFENTFVIQRVASTEIPATASDSSSILSLCSFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MZ40</accession>
    <name>A0A1C7MZ40_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">tRNA-splicing endonuclease subunit Sen15 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">A0J61_11557</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SEN15 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01002188">
        <property type="protein sequence ID" value="OBZ80394.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MZ40"/>
    <dbReference type="FunCoup" id="A0A1C7MZ40">
        <property type="interactions" value="1"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7MZ40"/>
    <dbReference type="InParanoid" id="A0A1C7MZ40"/>
    <dbReference type="OrthoDB" id="10002170at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006388">
        <property type="term" value="P:tRNA splicing, via endonucleolytic cleavage and ligation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1350.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018593">
        <property type="entry name" value="tRNA-endonuc_su_Sen15"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011856">
        <property type="entry name" value="tRNA_endonuc-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036167">
        <property type="entry name" value="tRNA_intron_Endo_cat-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28582">
        <property type="entry name" value="TRNA-SPLICING ENDONUCLEASE SUBUNIT SEN15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28582:SF1">
        <property type="entry name" value="TRNA-SPLICING ENDONUCLEASE SUBUNIT SEN15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09631">
        <property type="entry name" value="Sen15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53032">
        <property type="entry name" value="tRNA-intron endonuclease catalytic domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="tRNA-splicing endonuclease subunit Sen15" evidence="3">
        <location>
            <begin position="28"/>
            <end position="127"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF09631"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OBZ80394.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="134" mass="15459" checksum="AA49AAC863462C31" modified="2016-11-30" version="1">MSFNHKLGDIATRSAGFESSKTILSQAIYTDLVLGKKWKEVDYKPVQSLDICIFLAKDPDRHEQLFILPIFQENTKLSIERIKDIFDLLSEDLAIEEEIEKLTLAIYAPDSTIVYYHIKKGLTRPIQRNLEKST</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MZC0</accession>
    <name>A0A1C7MZC0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Tc1-like transposase DDE domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_09819</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000945">
        <property type="protein sequence ID" value="OBZ82132.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MZC0"/>
    <dbReference type="STRING" id="101091.A0A1C7MZC0"/>
    <dbReference type="InParanoid" id="A0A1C7MZC0"/>
    <dbReference type="OrthoDB" id="2283132at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="197"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ82132.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="197" mass="22781" checksum="4E32E6CC6EBF47B8" modified="2016-11-30" version="1" fragment="single">MADFHILKDGGITTEDGAEVMDYVIEEGEEFNLRNLTNLSEYDDCQAVPIELNAEDENLESRIPFVIEKNIYEKQTNKNNRAKSQLQELQKLHILELFDNKPYTTTDEVVDSLTKAFEGFTLKQSTVNSLILHECNLAIKRLQRQPKARNNPARIQVRYDWVMKYDSSGMNFLRNCIFIDESGFDINMRPSYGRSAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MZM4</accession>
    <name>A0A1C7MZM4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Methylglutaconyl-CoA hydratase, mitochondrial</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">auh</name>
        <name evidence="4" type="ORF">A0J61_09737</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the enoyl-CoA hydratase/isomerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000925">
        <property type="protein sequence ID" value="OBZ82211.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MZM4"/>
    <dbReference type="STRING" id="101091.A0A1C7MZM4"/>
    <dbReference type="InParanoid" id="A0A1C7MZM4"/>
    <dbReference type="OrthoDB" id="410701at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016836">
        <property type="term" value="F:hydro-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006635">
        <property type="term" value="P:fatty acid beta-oxidation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06558">
        <property type="entry name" value="crotonase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.226.10:FF:000009">
        <property type="entry name" value="Carnitinyl-CoA dehydratase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.12.10:FF:000001">
        <property type="entry name" value="Probable enoyl-CoA hydratase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.226.10">
        <property type="entry name" value="2-enoyl-CoA Hydratase, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.12.10">
        <property type="entry name" value="Lyase 2-enoyl-coa Hydratase, Chain A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018376">
        <property type="entry name" value="Enoyl-CoA_hyd/isom_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001753">
        <property type="entry name" value="Enoyl-CoA_hydra/iso"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014748">
        <property type="entry name" value="Enoyl-CoA_hydra_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11941">
        <property type="entry name" value="ENOYL-COA HYDRATASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11941:SF171">
        <property type="entry name" value="SD19268P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00378">
        <property type="entry name" value="ECH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="ClpP/crotonase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00166">
        <property type="entry name" value="ENOYL_COA_HYDRATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0456">Lyase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OBZ82211.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="281" mass="30826" checksum="2152158BC4FD3350" modified="2016-11-30" version="1">MSMFARRLFYFRGTTIRTISTQPSKEAYLEHVEGGISVLNLNRPSSRNALSVNLVSEFRQALSNVRFSNESRVLIVRSSTPGAFCSGADLKERANMTPAQVNQFLYSLRQAYRELETLPIPTIAAIDGPAFGGGLEMALSCDLRVAGPDAKMGLTETKLAIIPGAGGTQRLPRLIGIPKAKELIFTGQIMNSVTAKEYGVVNHVSQDSAFEKAMEIAQSILPQGPIAIRMAKMAIDRGAHLDMDSGLEVEQSYYAQVIPTEDRLEGLKAFKEKRKPVYKGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N023</accession>
    <name>A0A1C7N023_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_09527</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000870">
        <property type="protein sequence ID" value="OBZ82423.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N023"/>
    <dbReference type="STRING" id="101091.A0A1C7N023"/>
    <dbReference type="InParanoid" id="A0A1C7N023"/>
    <dbReference type="OrthoDB" id="10265994at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ82423.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="196" mass="22314" checksum="EAF4C2E37471742B" modified="2016-11-30" version="1">MDRKSRTSRSATLNGTNEEVNLWNQICNSLTKLESIQKDTTHVVTNINHIHTSLDSNQGIPATIGSKLVEYYKGCIELSSNEVKTINDIIEKLSILVALRDASEYNNDRLIYFAKQPRQKDSGHSLSLAVMKLKKNKSFDVKPIPDVKEASHFIELDSGQNIFTFYLGTEYSYQVEAHHFWKLGWIAHTKKVKTTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N025</accession>
    <name>A0A1C7N025_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Transposon TX1 uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">YTX2_3</name>
        <name evidence="8" type="ORF">A0J61_09546</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <cofactor evidence="5">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <text evidence="5">Probably binds two magnesium or manganese ions per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the DNA repair enzymes AP/ExoA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000875">
        <property type="protein sequence ID" value="OBZ82402.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N025"/>
    <dbReference type="InParanoid" id="A0A1C7N025"/>
    <dbReference type="OrthoDB" id="2443300at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003906">
        <property type="term" value="F:DNA-(apurinic or apyrimidinic site) endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008311">
        <property type="term" value="F:double-stranded DNA 3'-5' DNA exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008081">
        <property type="term" value="F:phosphoric diester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006284">
        <property type="term" value="P:base-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.10.10">
        <property type="entry name" value="Endonuclease/exonuclease/phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004808">
        <property type="entry name" value="AP_endonuc_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036691">
        <property type="entry name" value="Endo/exonu/phosph_ase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005135">
        <property type="entry name" value="Endo/exonuclease/phosphatase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22748">
        <property type="entry name" value="AP ENDONUCLEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22748:SF4">
        <property type="entry name" value="DNA-(APURINIC OR APYRIMIDINIC SITE) ENDONUCLEASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03372">
        <property type="entry name" value="Exo_endo_phos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56219">
        <property type="entry name" value="DNase I-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 5" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5" id="KW-0464">Manganese</keyword>
    <keyword evidence="2 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Endonuclease/exonuclease/phosphatase" evidence="7">
        <location>
            <begin position="9"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="12"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="44"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="154"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="156"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="6">
        <location>
            <position position="156"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="573"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007092"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR604808-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR604808-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF03372"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OBZ82402.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="573" mass="64678" checksum="25EE2D12AA1629C5" modified="2016-11-30" version="1" fragment="single">MVRSSFSIATLNCRGLRKAHNPSSSNSFIRYLRSLNIDILCLQETHAADAQIMAQFDMLFNTNSSLWSSHCGIVSLHRNLTIRALPSITQADGRFLCASVASDTDPSTPILHLLNIYAPAQSGPRQLFFQQLVDNPLLMSLLYRPELPTFILGDFNFNPSRRSNITDSWLELLDLHYTDCFEQEPTPTFTSASASRTRIDFVFCSTLHSLTITSTDHAFISSSWTDHDLLSVTFRPALQTTGPGLWKADPFLARIPSFREGLTSHIELFVASQNLLDDTCSSSAQDVWDTLKAEVKAYTRSYQFETNRWRSKTLKRYQSKRNRILRDYKNAAILCSLLPAVETMISSLQADIAHVNALKAGKFWREHGERSAGFLKNLASSRKLQRTIPALYDSSKEQLVTSTEDKTAAMADFYDQLYEPAPIDPAALEHLLATSAPQRASFTFXFLRSLRRVVELHSTRNLSVLGRATVSNVLLLSQCWHIMRVTPFPKSTLSSIQSIVSGFVSXGIFPRLSWKIMTSTKYCGGLGXLDPAVQQHALFYKWIDPLLFDRPYRTLVQQFLYVHLANQFQTANV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N041</accession>
    <name>A0A1C7N041_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Tetratricopeptide repeat protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">TTC1</name>
        <name evidence="3" type="ORF">A0J61_09433</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000849">
        <property type="protein sequence ID" value="OBZ82515.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N041"/>
    <dbReference type="STRING" id="101091.A0A1C7N041"/>
    <dbReference type="InParanoid" id="A0A1C7N041"/>
    <dbReference type="OrthoDB" id="1872379at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052769">
        <property type="entry name" value="TPR_domain_protein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46014">
        <property type="entry name" value="TETRATRICOPEPTIDE REPEAT PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46014:SF1">
        <property type="entry name" value="TETRATRICOPEPTIDE REPEAT PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13424">
        <property type="entry name" value="TPR_12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0802">TPR repeat</keyword>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="57"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="8"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="17"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ82515.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="235" mass="26624" checksum="13B2DD5EBA68659B" modified="2016-11-30" version="1">MAVIEEIHEQVSQAKTTHTEESTKDVITEGETDQDGDVFYDSTDYQLEELKQLLKEASEYKAKGNALFAQSEYQKAIAEYENALMVCPESQRKERSIYFSNIAACHLKLDQYKEARDMCTRSLELDSTYSKALLRRAQANERIGTSSAMSSALDDYKQLQKQAQDAYTLKECKRAQQELPGKIKIKMEQEKEEMIGKLKDLGNTLLGKFGLSTDNFQFTPDPSGSGGYSMNFVNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N0D8</accession>
    <name>A0A1C7N0D8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Reticulon-4-interacting protein 1, mitochondrial</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">Rtn4ip1</name>
        <name evidence="2" type="ORF">A0J61_09815</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000945">
        <property type="protein sequence ID" value="OBZ82136.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N0D8"/>
    <dbReference type="STRING" id="101091.A0A1C7N0D8"/>
    <dbReference type="InParanoid" id="A0A1C7N0D8"/>
    <dbReference type="OrthoDB" id="201656at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050700">
        <property type="entry name" value="YIM1/Zinc_Alcohol_DH_Fams"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11695">
        <property type="entry name" value="ALCOHOL DEHYDROGENASE RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11695:SF294">
        <property type="entry name" value="RETICULON-4-INTERACTING PROTEIN 1, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Alcohol dehydrogenase-like C-terminal" evidence="1">
        <location>
            <begin position="14"/>
            <end position="106"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00107"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ82136.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="140" mass="15274" checksum="4AF9A46DA6C65698" modified="2016-11-30" version="1">MQKRKALIVGVSGGVGSYGIQFAKAFHPENTAVAICSGRYAKFVKSLGADVVIDYTDKTAFEEFLKQEKGTFDYIFDCVGGDAYLKKLDPLLKKLGVYSIAAGPIEHIGSENVGLFSIASALYTIVRIKLFSPHTYKLIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N0R5</accession>
    <name>A0A1C7N0R5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_09262</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000810">
        <property type="protein sequence ID" value="OBZ82687.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N0R5"/>
    <dbReference type="STRING" id="101091.A0A1C7N0R5"/>
    <dbReference type="InParanoid" id="A0A1C7N0R5"/>
    <dbReference type="OrthoDB" id="2289909at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ82687.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="179" mass="20218" checksum="AFDEE96EE03379F6" modified="2016-11-30" version="1">MIVDSPGAEYTTRASDLSFKNRNTDSLLELESFDPQQDTPTEILHTVLLRIAKYLINDLVKLVLTDEQTKKVNAALDSYKSSLGFSRQFSRNLSHCGSFLGRDYKSLLQILPVILITEFPVAKDHLGRLIPCFTKLGKLCSLLFVRQVTENFTIYVDEVDAAAKDLIKSLYEYDCTCTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N0Z8</accession>
    <name>A0A1C7N0Z8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Rab GDP dissociation inhibitor</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">gdi1_1</name>
        <name evidence="3" type="ORF">A0J61_09197</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the Rab GDI family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000795">
        <property type="protein sequence ID" value="OBZ82752.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N0Z8"/>
    <dbReference type="FunCoup" id="A0A1C7N0Z8">
        <property type="interactions" value="642"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N0Z8"/>
    <dbReference type="InParanoid" id="A0A1C7N0Z8"/>
    <dbReference type="OrthoDB" id="9446342at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005093">
        <property type="term" value="F:Rab GDP-dissociation inhibitor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007264">
        <property type="term" value="P:small GTPase-mediated signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016192">
        <property type="term" value="P:vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.405.10:FF:000001">
        <property type="entry name" value="Rab GDP dissociation inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.405.10">
        <property type="entry name" value="Guanine Nucleotide Dissociation Inhibitor, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.519.10">
        <property type="entry name" value="Guanine Nucleotide Dissociation Inhibitor, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018203">
        <property type="entry name" value="GDP_dissociation_inhibitor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000806">
        <property type="entry name" value="RabGDI"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11787:SF8">
        <property type="entry name" value="RAB GDP DISSOCIATION INHIBITOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11787">
        <property type="entry name" value="RAB GDP-DISSOCIATION INHIBITOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00996">
        <property type="entry name" value="GDI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00892">
        <property type="entry name" value="RABGDI"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00891">
        <property type="entry name" value="RABGDIREP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU363124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ82752.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="441" mass="49090" checksum="FAA1E9FD91DC7F78" modified="2016-11-30" version="1">MDDNYDIIVLGTGLTECILSGIFSVEGKKVLHMDRNDYYGGESASLNLTQLYRKYRPDAEVPAELGRDRDYNIDLIPKFMMANGEIVRFLTHTDVTRYLEFKQIAGSFVYKDGKISKVPASETEAISTSLLGLAEKRRLQKFLEFIQNYKDSDEATHQGLDLDKNTMADVYAKFGLESATQQFIGHAMALHLDDEYINHPARETTEKIILYVASMARYGKSPYIYPLHGLGELPQSFARLSAIYGGTYMLDRAADEIIYENGVAVGIRSGTETAKAKQIICDPSYAKDKVKATGKVVRAICFLKHPIPDTSESDSVQIVIPQNELGRNHDVYVASVSSNHAVCPKDMYLAIVSTIVETEDPESEIKAGLDVLGPIHDKFISVSDIEEPLADGKADQVFVSKSYDATSHFETVCDDVKSIYKRMTGNDLVLKKRAEAEKTEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N186</accession>
    <name>A0A1C7N186_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Tumor susceptibility gene 101 protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">A0J61_09178</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endosome</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ubiquitin-conjugating enzyme family. UEV subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000791">
        <property type="protein sequence ID" value="OBZ82771.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N186"/>
    <dbReference type="STRING" id="101091.A0A1C7N186"/>
    <dbReference type="InParanoid" id="A0A1C7N186"/>
    <dbReference type="OrthoDB" id="306304at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000813">
        <property type="term" value="C:ESCRT I complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043130">
        <property type="term" value="F:ubiquitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072666">
        <property type="term" value="P:establishment of protein localization to vacuole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043162">
        <property type="term" value="P:ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd11685">
        <property type="entry name" value="UEV_TSG101-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.110.10">
        <property type="entry name" value="Ubiquitin Conjugating Enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052070">
        <property type="entry name" value="ESCRT-I_UEV_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037202">
        <property type="entry name" value="ESCRT_assembly_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017916">
        <property type="entry name" value="SB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016135">
        <property type="entry name" value="UBQ-conjugating_enzyme/RWD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008883">
        <property type="entry name" value="UEV_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23306:SF3">
        <property type="entry name" value="TUMOR SUPPRESSOR PROTEIN 101"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23306">
        <property type="entry name" value="TUMOR SUSCEPTIBILITY GENE 101 PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05743">
        <property type="entry name" value="UEV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09454">
        <property type="entry name" value="Vps23_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140111">
        <property type="entry name" value="Endosomal sorting complex assembly domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54495">
        <property type="entry name" value="UBC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51312">
        <property type="entry name" value="SB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51322">
        <property type="entry name" value="UEV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0967">Endosome</keyword>
    <keyword evidence="5 7" id="KW-0653">Protein transport</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0813">Transport</keyword>
    <feature type="domain" description="UEV" evidence="10">
        <location>
            <begin position="1"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="domain" description="SB" evidence="9">
        <location>
            <begin position="337"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="165"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="216"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="176"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="216"/>
            <end position="241"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009594"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022753"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00644"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51312"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51322"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="OBZ82771.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="13">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="398" mass="44755" checksum="18C79E888F356B62" modified="2016-11-30" version="1">MNIESWLRTVLQHYQDPDKTFRDVDAVLQTYLSLKPKMDAYTSNDGHTQLLLCLHGTIPITYRSIPYNIPVAFWIPREYPKIAPIPYVKPTSSMLIREGRHVDKSGMCYHHYRSSWSSDQKHTIVELVAILQQVFGQEPPVYTKPASMAVPSNSIGSPQFQESLLDKASPSPQHPPQRSFSNGSPSTVYTSPELHRRTGEGIYQLNQSLAGLSLNSPNPLSASTSTSTSLLSTPTTIPPNSDHSSLHNQLYRKVAERLQQHKMSVSEEVDKLLRQNQQLAGAGMTIEQIYRASTSIKQALEHNNRVLEAKSKEIDQVIEKVNAMPDVQVDEALCGTTVVANQLFELVADDNAISDTVYFLARALSTERIDLATFMKYTRILSREQFMKRALIKKITQT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N1P9</accession>
    <name>A0A1C7N1P9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_08928</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000738">
        <property type="protein sequence ID" value="OBZ83022.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N1P9"/>
    <dbReference type="InParanoid" id="A0A1C7N1P9"/>
    <dbReference type="OrthoDB" id="2287236at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="112"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ83022.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="112" mass="13257" checksum="59C945BAD38B7144" modified="2016-11-30" version="1" fragment="single">MFVLDLKSDKTCVLIRMNHYITRTSHQDKERDTGDMGFVQKWVDFLADAEKNRSFHRYSPERNGVVRLGNHVLFRNDDMKDMYKRLTSQLMPSSSPDFCSDLKRYLSEIMNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N1Q7</accession>
    <name>A0A1C7N1Q7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Transcriptional regulator prz1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">prz1_4</name>
        <name evidence="10" type="ORF">A0J61_09326</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000825">
        <property type="protein sequence ID" value="OBZ82626.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N1Q7"/>
    <dbReference type="STRING" id="101091.A0A1C7N1Q7"/>
    <dbReference type="InParanoid" id="A0A1C7N1Q7"/>
    <dbReference type="OrthoDB" id="8922241at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005694">
        <property type="term" value="C:chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045893">
        <property type="term" value="P:positive regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:001732">
        <property type="entry name" value="Zgc:162936"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000100">
        <property type="entry name" value="Zinc finger 45-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24394">
        <property type="entry name" value="ZINC FINGER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24394:SF44">
        <property type="entry name" value="ZINC FINGER PROTEIN 271-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 7" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="9">
        <location>
            <begin position="24"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="9">
        <location>
            <begin position="52"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="9">
        <location>
            <begin position="80"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="179"/>
            <end position="230"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OBZ82626.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="235" mass="27561" checksum="959D15D6B6401AE0" modified="2016-11-30" version="1">MSHTIASSKTNQNTITILTPDRPYACTHCHQTFSRTHNLKSHLATHSATRPFQCETCHHYFRRQHDLKRHQKLHTGERPYVCGNCRRSFSRLDALNRHLRVDGGTACHSNRKSSNKMPKKMEHKLYLSTPQPLTSFEHVSLPPLKLNRPSSDDDDDDLLTKPFRSWTYPALDRILPPPTRLQEQQIKSLERENASLRKEMQQLLSSRTRVHELEVENHLLRSLIEDQQQQQMYIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N218</accession>
    <name>A0A1C7N218_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">SWI/SNF and RSC complexes subunit Ssr4 C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">A0J61_08913</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000735">
        <property type="protein sequence ID" value="OBZ83038.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N218"/>
    <dbReference type="InParanoid" id="A0A1C7N218"/>
    <dbReference type="OrthoDB" id="5321006at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046464">
        <property type="entry name" value="SWI-SNF_Ssr4_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20497">
        <property type="entry name" value="SWI-SNF_Ssr4_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SWI/SNF and RSC complexes subunit Ssr4 C-terminal" evidence="3">
        <location>
            <begin position="78"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="129"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="37"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="76"/>
            <end position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF20497"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OBZ83038.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="254" mass="29519" checksum="171692C83E94621B" modified="2016-11-30" version="1">MTSAYYFNQQGAGVPMPQQRGMPGQIGINPAQGHFLQQQQQQQQQQQQQFRNQAQFNDARKRSHNKTPRPNVPIAEEAEEPSGDELDDISARDIAMARYKRNHDYLSEIFTPYHADTILPPSLDISFTKEELDKQIEEYTEKTKRHQTQYEQQLSSLQQEQTRFWEMMNQLNEANTLETIESTANTLAKQMDLQIEHSANPVKVVSIPGLQEEKPSFVQEMDTSMDMYFNDQRDQEESNDSFFNEMVNTEDMGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N397</accession>
    <name>A0A1C7N397_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 11">Protoporphyrinogen oxidase</fullName>
            <ecNumber evidence="4 11">1.3.3.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">hem14</name>
        <name evidence="13" type="ORF">A0J61_08845</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 11">Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10 11">
            <text>protoporphyrinogen IX + 3 O2 = protoporphyrin IX + 3 H2O2</text>
            <dbReference type="Rhea" id="RHEA:25576"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16240"/>
            <dbReference type="ChEBI" id="CHEBI:57306"/>
            <dbReference type="ChEBI" id="CHEBI:57307"/>
            <dbReference type="EC" id="1.3.3.4"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="11">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
        <text evidence="11">Binds 1 FAD per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 11">Porphyrin-containing compound metabolism; protoporphyrin-IX biosynthesis; protoporphyrin-IX from protoporphyrinogen-IX: step 1/1.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="11">Mitochondrion inner membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 11">Belongs to the protoporphyrinogen/coproporphyrinogen oxidase family. Protoporphyrinogen oxidase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.3.3.4" evidence="4 11"/>
    <dbReference type="EMBL" id="LUGH01000721">
        <property type="protein sequence ID" value="OBZ83106.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N397"/>
    <dbReference type="FunCoup" id="A0A1C7N397">
        <property type="interactions" value="244"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N397"/>
    <dbReference type="InParanoid" id="A0A1C7N397"/>
    <dbReference type="OrthoDB" id="438553at2759"/>
    <dbReference type="UniPathway" id="UPA00251">
        <property type="reaction ID" value="UER00324"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004729">
        <property type="term" value="F:oxygen-dependent protoporphyrinogen oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006782">
        <property type="term" value="P:protoporphyrinogen IX biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002937">
        <property type="entry name" value="Amino_oxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004572">
        <property type="entry name" value="Protoporphyrinogen_oxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050464">
        <property type="entry name" value="Zeta_carotene_desat/Oxidored"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00562">
        <property type="entry name" value="proto_IX_ox"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42923">
        <property type="entry name" value="PROTOPORPHYRINOGEN OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42923:SF3">
        <property type="entry name" value="PROTOPORPHYRINOGEN OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01593">
        <property type="entry name" value="Amino_oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 11" id="KW-0274">FAD</keyword>
    <keyword evidence="5 11" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="8 11" id="KW-0350">Heme biosynthesis</keyword>
    <keyword evidence="7 11" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9 11" id="KW-0627">Porphyrin biosynthesis</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amine oxidase" evidence="12">
        <location>
            <begin position="11"/>
            <end position="506"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002600"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012867"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00047554"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU367069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF01593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="OBZ83106.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="559" mass="61930" checksum="723D8C0F113459E6" modified="2016-11-30" version="1">MSNIAVLGGGISGLSAAYYLARLAPQTTKITLIEGKDRLGGWIKSRRVAPGKYTSQTELPPISTEKNSVLFEGGPRTLRPKGAGGTVMLEMIQHLGLDNDDLLAVPTTHPSAQNRYIYFNGEINQLPSSLSSALFNKPPVLKSVLLAGALESFRSSRFQQGQPKDGQEDESIYSFMERRFNQHAALHLMGAMTHGIYAGDVKQLSLQSTFRMLHEAERNYNGVIRGLMKGVNTETMRERGMAVRARDHRPEWFSQLEKMSVVGFKSGLESLPERLLTWLRQRPNVEILTNEPVESIHLLSNGKEGKIKTRSRELFVDHMISTLPSFTLDSLISSNRLPHLNHNPSVDVAVVNLAYPSDVKLAYDGFGFLTPHRDTPYPIPLPGTLGVIFDSNALSDQEKDYQPETTKLTAMIGGSDWEDAFGKTPIDQLDPDVAHDYACRIMRTFLNIDAKPTHAMVHLQKQCIPQYLVGHESRMRELHHALEKQYGQVLSVTGASYLGVSVPDCIKYSRMLVEELLVSGALGTRDKAVTGLGKTVQNNQELKDGARLSKGNTNVILKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N3Z1</accession>
    <name>A0A1C7N3Z1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">ER-derived vesicles protein ERV41</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">ERV41</name>
        <name evidence="7" type="ORF">A0J61_08172</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000605">
        <property type="protein sequence ID" value="OBZ83781.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N3Z1"/>
    <dbReference type="FunCoup" id="A0A1C7N3Z1">
        <property type="interactions" value="53"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N3Z1"/>
    <dbReference type="InParanoid" id="A0A1C7N3Z1"/>
    <dbReference type="OrthoDB" id="5541786at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030134">
        <property type="term" value="C:COPII-coated ER to Golgi transport vesicle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061852">
        <property type="term" value="C:retrograde transporter complex, Golgi to ER"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042802">
        <property type="term" value="F:identical protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006888">
        <property type="term" value="P:endoplasmic reticulum to Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006890">
        <property type="term" value="P:retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045888">
        <property type="entry name" value="Erv"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012936">
        <property type="entry name" value="Erv_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039542">
        <property type="entry name" value="Erv_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10984">
        <property type="entry name" value="ENDOPLASMIC RETICULUM-GOLGI INTERMEDIATE COMPARTMENT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10984:SF81">
        <property type="entry name" value="ER-DERIVED VESICLES PROTEIN ERV41"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07970">
        <property type="entry name" value="COPIIcoated_ERV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13850">
        <property type="entry name" value="ERGIC_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="Endoplasmic reticulum vesicle transporter N-terminal" evidence="6">
        <location>
            <begin position="12"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="domain" description="Endoplasmic reticulum vesicle transporter C-terminal" evidence="5">
        <location>
            <begin position="140"/>
            <end position="304"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF07970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF13850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OBZ83781.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="330" mass="36876" checksum="3FC1ACD5E1B345B7" modified="2016-11-30" version="1">MVLKKLVEKAAKIDAFPKVEDDNQQRSEKGGLLTVLVALCLCLLALSEFSDYRKIHTNYTFIVDSTIDTTMQVNIDLTVAMPCPSLMVHVVDATGQRTRLTDALRLIPAEFSATTATKHRQVDNPEYVHEIIQAASGKEYNHEIAKDMGACRLYGSLHVNKVASNLHITSDGHGYASHAHTSHDLLNFTHRIDEFSFGPFYPNLVNPLDDNLLTMVEIDFEVYTYTMAVVPTTYIDSSNNQLLTNQYSVIDSHKSYEEGQAVPGLFFKYDIEPISVQISESRQQSFFQFMVRLCGIIGGFAVTAGTCYRLVNFVLTGGREDSKLYSAIHA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N439</accession>
    <name>A0A1C7N439_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Autophagy-related protein 14</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">UVRAG</name>
        <name evidence="6" type="ORF">A0J61_08071</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ATG14 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000589">
        <property type="protein sequence ID" value="OBZ83882.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N439"/>
    <dbReference type="STRING" id="101091.A0A1C7N439"/>
    <dbReference type="InParanoid" id="A0A1C7N439"/>
    <dbReference type="OrthoDB" id="72772at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005768">
        <property type="term" value="C:endosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000323">
        <property type="term" value="C:lytic vacuole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032991">
        <property type="term" value="C:protein-containing complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000149">
        <property type="term" value="F:SNARE binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035493">
        <property type="term" value="P:SNARE complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018791">
        <property type="entry name" value="UV_resistance/autophagy_Atg14"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15157">
        <property type="entry name" value="UV RADIATION RESISTANCE-ASSOCIATED GENE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15157:SF5">
        <property type="entry name" value="UV RADIATION RESISTANCE-ASSOCIATED GENE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10186">
        <property type="entry name" value="ATG14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="599"/>
            <end position="630"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="313"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="615"/>
            <end position="630"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OBZ83882.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="665" mass="75453" checksum="9FD757BBFBE0E76B" modified="2016-11-30" version="1">MAENDSKIPLNPRQASIPFLYEVEGRRIRHIRSIAGRNIVWNDLATNQDNSESKNSKPMSRSESATMLSLAAVEDSSLMKRAYQKSKRQEKEQLSTLGLLDAYFTLHVADQDAPVFYKSEMIPNTVNPTFRALPFPFDWMNWYAAAGSLVIARLWVRHSIPDSAGQHTEPVLGYQDAEDHHGFQLLIEWQLDLSALSKVGNSISDLQCSFRENTLLFELEDGFYSTPDVKATKAVNQNKRLSMLDLDQKDTASIHSVNSSKGSKTKRSYTYNNIINTMTDCIYDTQRSSEEVRLSIQQVLEQEDHGLRLRRELNQHRCALVEIEAQIMQQKKRIQAKKELVRAKQQQLEKRRIALGDCNDRCLSNSEDLQENQIVLEKNISMRQNMHHTLSRRKKELIADLFSIYPIEQFSIRCIHLPNSVYDGQNEETIATALGYTAHLVSMLAYYLEIPLRYPTIPMGSRAYIRDLVSVISGSRDFPLYSKGVDRYRFEFGVFLLNKNIEQASKTNSYMRVCACVYVYLSFLFAEIILQLMNAYGLIVIDLRHTLPNIHYFIQAILTTSVTSGPTSMSVLSISSYANGSRNNNNEENGIRQHHNHLTLQPKPSIQPPSPSISNHSVSQSSKLNSPKLHSSAAFLNTPQAMAAPTILDPITTSSSRHDLVLSSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N451</accession>
    <name>A0A1C7N451_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_08508</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000662">
        <property type="protein sequence ID" value="OBZ83446.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="InParanoid" id="A0A1C7N451"/>
    <dbReference type="OrthoDB" id="2289980at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="193"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="372"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="22"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="147"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="193"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="391"/>
            <end position="400"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ83446.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="400" mass="44658" checksum="A5B8BCC349423B27" modified="2016-11-30" version="1">MSFKSKQRAKHGHLFGDDPLNASLQNTSDDPLFRPTSQSTRTDSPQDPLSHPDTSSSTPVFHSPRRAKQQGSIFGDIDVSKLGNKKTPLRSTATLRHYDLENEEDLFGGNRKKTSTKTSPSSSIHKRSPVLTHPELPPPLSKASPILTPTMQVSPXTTTSLKGITYPYTNYAKQPKDKIDEKTQERSSSFFRFFKTSSSSKTTSSASSVKSIPSGPIHEPEPIPQNRSKQPSQQQEEVVVIEDEATRAFADDMISFQSKPTNYLDIMTPELTMDALKLNTPPIPAPTTTSSSSVSTHSVDDPWLDPTLQPATVDLAIQVQDIEPQKRTAFADLINSWNTSTLKTHDVYLPKEQEEPDQFFDHVAEERRDIGFAGIEATPTRKEDNHPIEWVTEEEENPWH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N4W8</accession>
    <name>A0A1C7N4W8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Transcription elongation factor</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">tfs1</name>
        <name evidence="13" type="ORF">A0J61_08271</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Necessary for efficient RNA polymerase II transcription elongation past template-encoded arresting sites.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7 8">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the TFS-II family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000621">
        <property type="protein sequence ID" value="OBZ83679.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N4W8"/>
    <dbReference type="FunCoup" id="A0A1C7N4W8">
        <property type="interactions" value="779"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N4W8"/>
    <dbReference type="InParanoid" id="A0A1C7N4W8"/>
    <dbReference type="OrthoDB" id="44867at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001139">
        <property type="term" value="F:RNA polymerase II complex recruiting activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000977">
        <property type="term" value="F:RNA polymerase II transcription regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031440">
        <property type="term" value="P:regulation of mRNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031564">
        <property type="term" value="P:transcription antitermination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006362">
        <property type="term" value="P:transcription elongation by RNA polymerase I"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006368">
        <property type="term" value="P:transcription elongation by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00183">
        <property type="entry name" value="TFIIS_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd13749">
        <property type="entry name" value="Zn-ribbon_TFIIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.20.25.10:FF:000001">
        <property type="entry name" value="Probable Transcription elongation factor S-II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.472.30:FF:000003">
        <property type="entry name" value="Transcription elongation factor S-II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.25.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.930.10">
        <property type="entry name" value="Conserved domain common to transcription factors TFIIS, elongin A, CRSP70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.30">
        <property type="entry name" value="Transcription elongation factor S-II, central domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035100">
        <property type="entry name" value="TF_IIS-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003617">
        <property type="entry name" value="TFIIS/CRSP70_N_sub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035441">
        <property type="entry name" value="TFIIS/LEDGF_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003618">
        <property type="entry name" value="TFIIS_cen_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036575">
        <property type="entry name" value="TFIIS_cen_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017923">
        <property type="entry name" value="TFIIS_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006289">
        <property type="entry name" value="TFSII"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001222">
        <property type="entry name" value="Znf_TFIIS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01385">
        <property type="entry name" value="TFSII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11477:SF0">
        <property type="entry name" value="IP08861P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11477">
        <property type="entry name" value="TRANSCRIPTION FACTOR S-II ZINC FINGER DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08711">
        <property type="entry name" value="Med26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07500">
        <property type="entry name" value="TFIIS_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01096">
        <property type="entry name" value="Zn_ribbon_TFIIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006704">
        <property type="entry name" value="TF_IIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00510">
        <property type="entry name" value="TFS2M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00509">
        <property type="entry name" value="TFS2N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00440">
        <property type="entry name" value="ZnF_C2C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47676">
        <property type="entry name" value="Conserved domain common to transcription factors TFIIS, elongin A, CRSP70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46942">
        <property type="entry name" value="Elongation factor TFIIS domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57783">
        <property type="entry name" value="Zinc beta-ribbon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51321">
        <property type="entry name" value="TFIIS_CENTRAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51319">
        <property type="entry name" value="TFIIS_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00466">
        <property type="entry name" value="ZF_TFIIS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51133">
        <property type="entry name" value="ZF_TFIIS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="13" id="KW-0251">Elongation factor</keyword>
    <keyword evidence="2 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 7 8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0804">Transcription</keyword>
    <keyword evidence="8" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="4 8" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 6 8" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="TFIIS N-terminal" evidence="11">
        <location>
            <begin position="5"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="domain" description="TFIIS central" evidence="12">
        <location>
            <begin position="151"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="domain" description="TFIIS-type" evidence="10">
        <location>
            <begin position="268"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="76"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="82"/>
            <end position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00472"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU368078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51319"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51321"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="OBZ83679.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="310" mass="34037" checksum="A1A030E2068CDB4A" modified="2016-11-30" version="1">MSVEEQINKAKSSLNTALERENVQTCLEILDTLSKLEVTGDLLKKTDIGKVIGKLRTHKDPKLSVKAKLVVKKWKDDVVRQTPPQSSTPVNKPPSQTSTPINKPPSISVNVSKRTSPTSSQASSPKTPPTEGPPRTVKSDEVTYTSTGNVPRNKTIELMYASIGYGSGADSELLMKRAIAIEKTIFREYGDINQDYKNKARSLALNLKNKANPGLRESVVSGELPVEKLCKMSVEAMASEEAQARDRKLAEEALFKARGAESAQAETDMFKCGKCGGRKCTYFQMQTRSADEPMTTFVTCVGCGNHWKFC</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N576</accession>
    <name>A0A1C7N576_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_07671</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000531">
        <property type="protein sequence ID" value="OBZ84283.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N576"/>
    <dbReference type="InParanoid" id="A0A1C7N576"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ84283.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="76" mass="8553" checksum="FCAE5000B4C97275" modified="2016-11-30" version="1">MNCCSKTPTLCHINQKQDCCFENESTQPISGNYSPSTVFADNNSACYQLKSGFCQYCGVDVSFLAHEFWCRFSTTD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N582</accession>
    <name>A0A1C7N582_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">A0J61_09456</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000854">
        <property type="protein sequence ID" value="OBZ82494.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N582"/>
    <dbReference type="STRING" id="101091.A0A1C7N582"/>
    <dbReference type="InParanoid" id="A0A1C7N582"/>
    <dbReference type="OrthoDB" id="2290256at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="461"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="110"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="193"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="524"/>
            <end position="544"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="388"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="37"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="121"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="202"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OBZ82494.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="564" mass="64983" checksum="1793B83B8E034151" modified="2016-11-30" version="1" fragment="single">KMTHCCIERPSPSIQTTSTPASSVSSLENPTDTKRASWLRKLKPNRSRSSRKENNILSSDDLPDGKTPAAYMVEQFYQKHGRSPALEDQSSDVDSFVRQRRHSFDSFQSYHSDTLFLPQDESGEDEDEERTQGEVETEGSEENISKNKVVRLLFDYDSLPTELKSLIDAYEYKGKVEHVQKTVWYEQKDKGDDALSSVLTTEGDEDEDEENEEEEEEEEDAVYFKQLIKGKVDQANFKSNPVRDIAILTTTDAEPIEFTKLVQLPSEKPNEHGPLLNLQISLVDPDRDSQQEEEEIEIQEMIHGLDLKLASLNAFEAYSKQFLQDHFDANLLNSNRPLTRTTSNPQLKEMKQEEASFLTGHRHSMYENNHDYAEDTFDNRVKSTAFLINSLAEELKEFKQSLDQTELLIQDVQLDMDDFRNRMEVYIKDIPESHYSALKQLELDIESILSKRAKNPWMDTGYALLSYLLTLFALGVWIVIYMIKLSKKIVLFPFKLWKDYSDYLVERNKAVKKASMRTVSTSRRSSQANLIGRTQERASSSSSFVTAYHGDDHLFPQRPPSKKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N5A4</accession>
    <name>A0A1C7N5A4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Metal-response element-binding transcription factor 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">MTF2</name>
        <name evidence="7" type="ORF">A0J61_07739</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000541">
        <property type="protein sequence ID" value="OBZ84211.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N5A4"/>
    <dbReference type="STRING" id="101091.A0A1C7N5A4"/>
    <dbReference type="InParanoid" id="A0A1C7N5A4"/>
    <dbReference type="OrthoDB" id="4080456at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.980.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053835">
        <property type="entry name" value="ASH2L-like_WH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019786">
        <property type="entry name" value="Zinc_finger_PHD-type_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001965">
        <property type="entry name" value="Znf_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019787">
        <property type="entry name" value="Znf_PHD-finger"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21198">
        <property type="entry name" value="ASH2L-like_WH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00249">
        <property type="entry name" value="PHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01359">
        <property type="entry name" value="ZF_PHD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50016">
        <property type="entry name" value="ZF_PHD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="PHD-type" evidence="6">
        <location>
            <begin position="24"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="186"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="192"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="223"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="240"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="263"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="280"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="291"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="303"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OBZ84211.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="303" mass="35379" checksum="C226A643716BA63F" modified="2016-11-30" version="1" fragment="single">MKKKFPYNIEGLTWDAQHNTNMEDKYCYCGKGLKESQPMIRCDRCRQLFHRDCIECMKKPLLFGDTFGTFKCSVCNQGPETFERKPVSWITIVHLVIYNLMKHAMVEDAKKPKKDKREHYYFRWKEDVCAFIDDYWDYLMPDKTRSATWNNTIASVLSTHSNIFLSGLEKLHQSAWWTLRDFEPPKNEKKTKAAARPKPNIKRTLKRTTSQDAINNRPKRVKKDTESKPKQQEPQEDLLDLSSLSELSSAADSSDSENEIPTKKKNSQHQKKPVIVQTQEETEPLTEVEQQEQTVTITQPSVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N5B6</accession>
    <name>A0A1C7N5B6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">uracil phosphoribosyltransferase</fullName>
            <ecNumber evidence="4">2.4.2.9</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">FUR1</name>
        <name evidence="11" type="ORF">A0J61_07740</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Pyrimidine metabolism; UMP biosynthesis via salvage pathway; UMP from uracil: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the UPRTase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.2.9" evidence="4"/>
    <dbReference type="EMBL" id="LUGH01000541">
        <property type="protein sequence ID" value="OBZ84207.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N5B6"/>
    <dbReference type="FunCoup" id="A0A1C7N5B6">
        <property type="interactions" value="182"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N5B6"/>
    <dbReference type="InParanoid" id="A0A1C7N5B6"/>
    <dbReference type="OrthoDB" id="106623at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004845">
        <property type="term" value="F:uracil phosphoribosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008655">
        <property type="term" value="P:pyrimidine-containing compound salvage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd06223">
        <property type="entry name" value="PRTases_typeI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.2020:FF:000023">
        <property type="entry name" value="Probable uracil phosphoribosyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2020">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029057">
        <property type="entry name" value="PRTase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000836">
        <property type="entry name" value="PRTase_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF001097">
        <property type="entry name" value="PRK00129.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14681">
        <property type="entry name" value="UPRTase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53271">
        <property type="entry name" value="PRTase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0021">Allosteric enzyme</keyword>
    <keyword evidence="6 11" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="9" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 11" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Phosphoribosyltransferase" evidence="10">
        <location>
            <begin position="17"/>
            <end position="219"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011894"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF14681"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="OBZ84207.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="220" mass="24630" checksum="8A890C951B9475BC" modified="2016-11-30" version="1">MSAENYKLPEQVKLLAQTTQLKGLMTIIRDKNTPRADFIFYADRIIRLLVEEGLNHLPVVDQTVLTPTGSEYKGISFEGRICGVSIMRAGEAMEQGLRECCRSVRIGKILIQRDEETHQPKLYYSKLPKDISSRYVLLLDPMLATGGSAMQAVQVLLDNNVKEERIIFLNLIAAPEGIDAFIKAFPKVKIVIGALDLCLNEEKYIIPGCGDFGCRYFGTD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N600</accession>
    <name>A0A1C7N600_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_07372</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000494">
        <property type="protein sequence ID" value="OBZ84575.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N600"/>
    <dbReference type="InParanoid" id="A0A1C7N600"/>
    <dbReference type="OrthoDB" id="2441427at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ84575.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="185" mass="21095" checksum="C19A296DAC7019C8" modified="2016-11-30" version="1">MLNQPPNNNNNNSFESDLEVIENAMNNMVQGAFAMLFREMTNGSGIFESVITDPHVTTIMDGRNLDHSHTHDDFGGSDFKRLASKSKQKQLTLESASNSIFDYLVPTKRLLFNRDSYENNNAAEGWSFSSTSQRTVYHPNGTQETILTRKVNGNTETTRRIQYPDGRTEETRENKSSIWNKLGWH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N6J2</accession>
    <name>A0A1C7N6J2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Grainyhead-like protein 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">Grhl2</name>
        <name evidence="7" type="ORF">A0J61_07695</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000535">
        <property type="protein sequence ID" value="OBZ84256.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N6J2"/>
    <dbReference type="STRING" id="101091.A0A1C7N6J2"/>
    <dbReference type="InParanoid" id="A0A1C7N6J2"/>
    <dbReference type="OrthoDB" id="7680836at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001228">
        <property type="term" value="F:DNA-binding transcription activator activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007604">
        <property type="entry name" value="CP2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057520">
        <property type="entry name" value="GRHL1/CP2_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040167">
        <property type="entry name" value="TF_CP2-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11037:SF20">
        <property type="entry name" value="PROTEIN GRAINYHEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11037">
        <property type="entry name" value="TRANSCRIPTION FACTOR CP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04516">
        <property type="entry name" value="CP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25416">
        <property type="entry name" value="GRHL1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51968">
        <property type="entry name" value="GRH_CP2_DB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Grh/CP2 DB" evidence="6">
        <location>
            <begin position="88"/>
            <end position="321"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OBZ84256.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="507" mass="57995" checksum="D9DD10E9A694921C" modified="2016-11-30" version="1">MLSSSHLSFSTESYPYYYYPVQQKILYNSPPSFNSPLSSPQILNHYNYPTMESYNMSSPHMPMSISPSSPTSIVSTAQHHRYRSQSNSPIRFEVRLEAPTAASQKSDEPALTYLNKGQYYTIVLNDTQRYDGDINSTVSITFHDENHRMSATDYWKFWLTQQKDSDEAKAVELDLARSSGAQAIDGRMFDRVSFKWNGKQGATIHIRFNCLSTDFSRIKGVKGIPLRLQIQSEQLPSEQDIRFSQFFNEKTYCRIKLFRDKGAERKNKDDAKHIERQLEKLRGKNGEPHPFWLTYSPTLPYTLFKELVSPEDDLQPSYTSIFENKGLLQPQHPQQHIAGGSIGSPTHTGALLPPSILASSPSVPSMLPTSMKRSFSSYSESHAEILSSYSSQINNNLALDVDPTYIPQRRRRVAKLSLLVRFMTSNVFRAIYLEHLTLSEFIDKVSQRLDIKQTIVNVYRKIDNKDKSIVVKVDNEVIQDLKEEQDIRIEIENDGLGPDAVNLILHF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N6T1</accession>
    <name>A0A1C7N6T1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">GTPase-activating protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">gap1_0</name>
        <name evidence="4" type="ORF">A0J61_07601</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000522">
        <property type="protein sequence ID" value="OBZ84346.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N6T1"/>
    <dbReference type="FunCoup" id="A0A1C7N6T1">
        <property type="interactions" value="4"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N6T1"/>
    <dbReference type="InParanoid" id="A0A1C7N6T1"/>
    <dbReference type="OrthoDB" id="775356at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005938">
        <property type="term" value="C:cell cortex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046580">
        <property type="term" value="P:negative regulation of Ras protein signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05132">
        <property type="entry name" value="RasGAP_GAPA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.506.10">
        <property type="entry name" value="GTPase Activation - p120gap, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000593">
        <property type="entry name" value="RasGAP_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023152">
        <property type="entry name" value="RasGAP_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001936">
        <property type="entry name" value="RasGAP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008936">
        <property type="entry name" value="Rho_GTPase_activation_prot"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14149:SF17">
        <property type="entry name" value="GTPASE-ACTIVATING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14149">
        <property type="entry name" value="RAS GTPASE-ACTIVATING PROTEIN WITH IQ MOTIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00616">
        <property type="entry name" value="RasGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03836">
        <property type="entry name" value="RasGAP_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00323">
        <property type="entry name" value="RasGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48350">
        <property type="entry name" value="GTPase activation domain, GAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143885">
        <property type="entry name" value="RGC domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00509">
        <property type="entry name" value="RAS_GTPASE_ACTIV_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50018">
        <property type="entry name" value="RAS_GTPASE_ACTIV_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ras-GAP" evidence="3">
        <location>
            <begin position="183"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="685"/>
            <end position="704"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="55"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="685"/>
            <end position="695"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50018"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OBZ84346.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="823" mass="93955" checksum="746DB659B6BF156D" modified="2016-11-30" version="1">MSTQDGSLSVEIRNGSVVRRAVTAAAANIRRRSTQHRFSQQYSVSLFYAMAAEEDSEVEDELALAQKRLRDLKTKISKESKNNFLLERDVRVLDSRIALLIQNRMALDDSSENIMNSIEDTDYSDTSSNLDSRKLQLYGNLFFLLQTEPQHIATLCRLVSLSEIDMLLQTVMFTLYGNQYESREENLLLTMFQSVLAAQFEATVEFGSLLRANTPVSRMLTTYTRRGPGQSYLKFVLSKNINQLLERKRDLNLQINPLKVFDEVVAEMEEKGTCPPDFCKSVTPEIAASNSEVQAKIKPRLEQLIAIANEYLQVIIDSLDYVPYGIRWVCKQIRSLTKRKYPEASESSISSLIGGFFFLRFINPAIVTPNAYMLIESNPDQNVRTTLTLIAKMLQNLANKPSYAKEAYMIPTNSFVTDNKQRINEFLNDLCEVSDFYDTLEMDQYMALSKRDLSINITPNEIYNTQALLKKHLDKLAPEPTHHLHILLDDLGPNVPEQIPRKNNRPIQLMLESRWEASSIIAQEQESLLNTDGENITQNDLLYMETKSTFVQIVRSLPHTIRNLDLIHIMEAAGSAKDTQIAIKGMKAQALLFELETAGVVNQQDGYRLLTKEIQLELSHLGDLKTRVINEMESLIHVYKAIIDHNRYLQSQLDTYKTYLNNVRAQSGHLTTEIPVQKRSGLWSSSASSDLSQTSNEYNTDPSCLKKPGDKLRKKSSGIFKFSHQQLEKDGVIVESDVPDQRKANIFLTLQCPMTGTFIISLHYKGRDKPILELDLKLDDLLEKQKEHDSILDLEYIKLNTSKVVQLLNKNFKSKNAVRRNFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N6Y4</accession>
    <name>A0A1C7N6Y4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Serine/threonine-protein phosphatase 2A activator</fullName>
            <ecNumber evidence="6">5.2.1.8</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Phosphotyrosyl phosphatase activator</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">RRD2</name>
        <name evidence="7" type="ORF">A0J61_08863</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 9">
            <text>[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)</text>
            <dbReference type="Rhea" id="RHEA:16237"/>
            <dbReference type="Rhea" id="RHEA-COMP:10747"/>
            <dbReference type="Rhea" id="RHEA-COMP:10748"/>
            <dbReference type="ChEBI" id="CHEBI:83833"/>
            <dbReference type="ChEBI" id="CHEBI:83834"/>
            <dbReference type="EC" id="5.2.1.8"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the PTPA-type PPIase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.2.1.8" evidence="6"/>
    <dbReference type="EMBL" id="LUGH01000724">
        <property type="protein sequence ID" value="OBZ83084.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N6Y4"/>
    <dbReference type="FunCoup" id="A0A1C7N6Y4">
        <property type="interactions" value="70"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N6Y4"/>
    <dbReference type="InParanoid" id="A0A1C7N6Y4"/>
    <dbReference type="OrthoDB" id="16120at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000159">
        <property type="term" value="C:protein phosphatase type 2A complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008160">
        <property type="term" value="F:protein tyrosine phosphatase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007052">
        <property type="term" value="P:mitotic spindle organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006970">
        <property type="term" value="P:response to osmotic stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd04087">
        <property type="entry name" value="PTPA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.120.1150:FF:000002">
        <property type="entry name" value="Serine/threonine-protein phosphatase 2A activator"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004327">
        <property type="entry name" value="Phstyr_phstse_ac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043170">
        <property type="entry name" value="PTPA_C_lid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037218">
        <property type="entry name" value="PTPA_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10012">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN PHOSPHATASE 2A REGULATORY SUBUNIT B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10012:SF5">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN PHOSPHATASE 2A ACTIVATOR 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03095">
        <property type="entry name" value="PTPA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016325">
        <property type="entry name" value="Phstyr_phstse_ac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140984">
        <property type="entry name" value="PTPA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 6" id="KW-0413">Isomerase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6" id="KW-0697">Rotamase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU361210"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OBZ83084.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="356" mass="41056" checksum="9CC4046F4C9240CC" modified="2016-11-30" version="1">MSFRVPTKRIITKEDLDEFLQSQAYHEYIGYIERLNESVKNTKIDPSMPVSPNVQKTLDILETLLNWIKEIPPVENEKSRFGNPAFRTFYDKIQENIHDVFKDLVPKEAIEEVARYFYESFGNRKRIDYGTGHEANFIAWLLCLDKLAILTPEDDQTVVLTVFVKYIKVMRQLQFHYWLEPAGSHGVWGLDDYHFLPFMFGSSQLFDHKHIKPKSIHDQDIVEQFSAEYMYLACIQFINSVKTTASLRWHSPMLDDISACKTWIKVNQGMVKMYKAEVLSKLPIMQHFMFGSLICFEGGHAESEEMEDACGHHHTSTKQDVFALGQEYPDCCGIPIPSAIAAAAATQTKPRPIPFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N715</accession>
    <name>A0A1C7N715_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_07564</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000517">
        <property type="protein sequence ID" value="OBZ84379.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N715"/>
    <dbReference type="InParanoid" id="A0A1C7N715"/>
    <dbReference type="OrthoDB" id="2279365at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="133"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="318"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="27"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="145"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="186"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="209"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="322"/>
            <end position="331"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ84379.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="346" mass="39299" checksum="0AB084198E89A29C" modified="2016-11-30" version="1">MPPKTANKKKLAANDNHRKINTYFKPTPKEPIKRKLETNENSELHEESHKRTPSPPNTKPMESKKGLSIQNRPVLRDINPAQSLNPEAKSDTHSIRPTFAVLSDADIERGLEKATTPPISIYCDEKPIFVYRDSQESDKTRNTHKQALNTQTIPDSESQWTEDTHSPLHVFEDEEPFEISASQVQEKADYEKYGSRKRKTDENAAEQRPEEDEDSNFEDSDLFTKTVDTTVRFRPTSVEQDKSEDEEDDLFFSSALQPNIGGSTFFDDEKDDTYIDHHEFSVASDYADPELEFSIGEDEQPTLSPEVVEAVSQVHVPYPNPRGKDILEKLDLSPSSSSSVDDELPT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N765</accession>
    <name>A0A1C7N765_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Pentacotripeptide-repeat region of PRORP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_07036</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000456">
        <property type="protein sequence ID" value="OBZ84911.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N765"/>
    <dbReference type="STRING" id="101091.A0A1C7N765"/>
    <dbReference type="InParanoid" id="A0A1C7N765"/>
    <dbReference type="OrthoDB" id="185373at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007005">
        <property type="term" value="P:mitochondrion organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006396">
        <property type="term" value="P:RNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051114">
        <property type="entry name" value="Mito_RNA_Proc_CCM1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002885">
        <property type="entry name" value="PPR_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00756">
        <property type="entry name" value="PPR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47934:SF6">
        <property type="entry name" value="MITOCHONDRIAL GROUP I INTRON SPLICING FACTOR CCM1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47934">
        <property type="entry name" value="PENTATRICOPEPTIDE REPEAT-CONTAINING PROTEIN PET309, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13812">
        <property type="entry name" value="PPR_3"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51375">
        <property type="entry name" value="PPR"/>
        <property type="match status" value="6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="repeat" description="PPR" evidence="1">
        <location>
            <begin position="362"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="repeat" description="PPR" evidence="1">
        <location>
            <begin position="397"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="repeat" description="PPR" evidence="1">
        <location>
            <begin position="432"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="repeat" description="PPR" evidence="1">
        <location>
            <begin position="467"/>
            <end position="501"/>
        </location>
    </feature>
    <feature type="repeat" description="PPR" evidence="1">
        <location>
            <begin position="537"/>
            <end position="571"/>
        </location>
    </feature>
    <feature type="repeat" description="PPR" evidence="1">
        <location>
            <begin position="572"/>
            <end position="606"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00708"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ84911.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="662" mass="75514" checksum="4DDD5D607DCDAC34" modified="2016-11-30" version="1">MRKPTTHFKDVSRLLSATIDSGRSFAMSHNCRQITQLKALLWEAFPQHNSCSSQSIPHSRRSPLIAALRNMSTSSSAVLIDKPLSSTSVMPRPSHRLPGSIFNMSAQLTFADLDCAIQAHNADKAWSIFATLASRKNEIIPLTLCCSLYALLIYAKRLSSSPNKANKLRQRQVGQLLDYVELQSSRELFLSSVQEIPISSQKQLSRAIKSGNYKEAWQIFYRSYRENQRKNGNEQLKLSRNTCLKLMLMVMNDKSLNKNQLKMRLQLIALHGAGTSEFDSRYLSAADVCRLAHICHGYQKNKLTAHELIDDYVLGLEKKKQMHRADALDELIWRMLIHGDIEKAQQVLHLVTEKLVDKVEINETVFINMMNAYRKQKRYHESLKLFEQLLETGKRPTVKAFNAVLQVFTAQASVEQAEYIFESMLQLDVEPDAATFTEMIKVGANAGQMRHCIHYYSKMLQTNVKPNAYTYSALIEASGRRNDTNLMLRWFHTMLAQEIEPNGIVLASILRAFSKQNMSDVALQVAQQAAMTGIKTDTVLYTILLKMQAESQGVEGALNIHRDMLADSIQPNTYTYTTLIDICGSSNMPETAEKIFDLMKKSRRHKPNTVTYSALIDAWLKARRKDKAESVIFDFLKECKSDRSGRFWLDSRIRDRLKMRCC</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N7P3</accession>
    <name>A0A1C7N7P3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Trans-acting T-cell-specific transcription factor GATA-3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">GATA3</name>
        <name evidence="4" type="ORF">A0J61_06877</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000436">
        <property type="protein sequence ID" value="OBZ85077.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N7P3"/>
    <dbReference type="STRING" id="101091.A0A1C7N7P3"/>
    <dbReference type="InParanoid" id="A0A1C7N7P3"/>
    <dbReference type="OrthoDB" id="515401at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00202">
        <property type="entry name" value="ZnF_GATA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.50.10">
        <property type="entry name" value="Erythroid Transcription Factor GATA-1, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000679">
        <property type="entry name" value="Znf_GATA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013088">
        <property type="entry name" value="Znf_NHR/GATA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00320">
        <property type="entry name" value="GATA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00401">
        <property type="entry name" value="ZnF_GATA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57716">
        <property type="entry name" value="Glucocorticoid receptor-like (DNA-binding domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50114">
        <property type="entry name" value="GATA_ZN_FINGER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="GATA-type" evidence="3">
        <location>
            <begin position="249"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="226"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="241"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="258"/>
            <end position="268"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00094"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50114"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OBZ85077.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="351" mass="39079" checksum="42A620DA878B01B7" modified="2016-11-30" version="1">MTELAYCTNQVLRASSMNNEQSPIAHSTASNSSIAAETPSIMSHSSSVSPLGDYALSCPAGPIERGYFTSTAPAVHNVLSAMDGYSDRFNPEAMGYSSSSGSPDEHAVLLDSFHGSISPPVLVSDGSLLRLSAENMASQASSQSMLSFYRHPEQQQAHVLSNYYDQDYINHRRHSTSIVPLYHQDFDSPNSATVPQVSLDSPSGYESISKKPYYHSDCRRNSFPEHVCQKSHSHSTEKKHSSSKKQSRHKDKKRCTNCHASTSPSWRRSISKDTKGNLLCNACGLYEKTAKKKRMLLTQPDGNTKVIRKRDFREFKCSNCKSDTGARWRKIPNSKEDRVVCEKCARLLARR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N805</accession>
    <name>A0A1C7N805_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Protein SKT5</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">SKT5_0</name>
        <name evidence="3" type="ORF">A0J61_06708</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000418">
        <property type="protein sequence ID" value="OBZ85242.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N805"/>
    <dbReference type="STRING" id="101091.A0A1C7N805"/>
    <dbReference type="InParanoid" id="A0A1C7N805"/>
    <dbReference type="OrthoDB" id="272077at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051726">
        <property type="entry name" value="Chitin_Synth_Reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006597">
        <property type="entry name" value="Sel1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46430:SF1">
        <property type="entry name" value="CHITIN SYNTHASE REGULATOR SKT5-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46430">
        <property type="entry name" value="PROTEIN SKT5-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08238">
        <property type="entry name" value="Sel1"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SMART" id="SM00671">
        <property type="entry name" value="SEL1"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81901">
        <property type="entry name" value="HCP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="235"/>
            <end position="258"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ85242.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="258" mass="28661" checksum="7840587778F1F330" modified="2016-11-30" version="1">MHSRDSSIDRAAKCYEDGLGCRRDYAKAVQFYRKAATLSHPGAMYRLGVAEVNGELGISKNPRDGVKWLKRSAEAATSEYPHAIHELALLHERGIPNVVFVDLSYAVSLYAQAAELGYAPSAFRLGECYEYGKLECNPDPAMSIHFYTIAAQQGHREACFALTAWYLVGSPQVLPQSDEDAYLWAKRAAEKELPKAEYAVGYFTEVGIGVVKNPNEAMEWYKKAAEHGDKRAIQRLQGKGVEQKSKKKSGSQDDCTIM</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N8T7</accession>
    <name>A0A1C7N8T7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_06401</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000384">
        <property type="protein sequence ID" value="OBZ85555.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N8T7"/>
    <dbReference type="STRING" id="101091.A0A1C7N8T7"/>
    <dbReference type="InParanoid" id="A0A1C7N8T7"/>
    <dbReference type="OrthoDB" id="2384193at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="34"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="131"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="168"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="252"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="281"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="511"/>
            <end position="536"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="289"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="511"/>
            <end position="520"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="521"/>
            <end position="536"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="536"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ85555.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="536" mass="61553" checksum="5003DFCF7A2E0B76" modified="2016-11-30" version="1" fragment="single">MISFGYLYIWYTYRVWTLDKFSCMSLEKFKQGELKSIVTLLILFMIPFQLFYDITSVKIKYEEGFADLLGRIFTKPEIMWTKADRNLVVPTEYSLCIGFSLQTGTLVLLQCFWNYLSNSVAKKSFMSSKEFMFYICWTFSSFIIFPLLQYNFSRDVYEATYKEIIPEMVYGIELFIVACLGVVSHFRFKKLLRSSRNTVNGRSIQQKVLYFQEINIILSTVLFGHGTLLTILSCDGLTKRKFLNIHKFTADFFICNINMCAVITWLCMILIFHPKHNLSPEANSDENTNDSQRPLNNQSGLSSANTFPQSCQYSQARSMSEYPYPSVHPLSKQEVSVADTFSHPFDNSFKYPTYQADLGYYRDKNNSITSSIPSVSTIVSRQPSYSSKLRLSKALPLRETAADLFQPMPDSDRRKSYVIMHPLSSPSDDSFQDLTSFQRDEDISIPPILPPVRKRSEPIIHHPDFRRYTNSVAIPLIDEDLEDFGVYKKAGPSEEQPQMIDIDLESSLQNYGLSSLSQQIAPPPSVPPPPIPHNCN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N9A2</accession>
    <name>A0A1C7N9A2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_06763</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000424">
        <property type="protein sequence ID" value="OBZ85186.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N9A2"/>
    <dbReference type="InParanoid" id="A0A1C7N9A2"/>
    <dbReference type="OrthoDB" id="124998at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47150:SF5">
        <property type="entry name" value="OS07G0546750 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47150">
        <property type="entry name" value="OS12G0169200 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="145"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="154"/>
            <end position="166"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ85186.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="166" mass="18730" checksum="727E23B478AE664F" modified="2016-11-30" version="1">MSIQSEDSIEDNSPILMNFFDFKIAVINERQRELEEESTERIRYAFGRRFIRRDRNVQEAGVLEADAKFALLKDAGGLPGASTRQEVASGIRLLAKGSDFDAMDEYFEKSKSSSADYFVRFLKTIIKIFGNEYLRKPNAVGATLIGTTSDPPEDAPKETYQDLKSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N9G4</accession>
    <name>A0A1C7N9G4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">GBD/FH3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">A0J61_06211</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000365">
        <property type="protein sequence ID" value="OBZ85737.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N9G4"/>
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    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
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        <property type="term" value="F:actin filament binding"/>
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    </dbReference>
    <dbReference type="GO" id="GO:0031267">
        <property type="term" value="F:small GTPase binding"/>
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        <property type="project" value="InterPro"/>
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    <dbReference type="GO" id="GO:0016477">
        <property type="term" value="P:cell migration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
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        <property type="term" value="P:cortical actin cytoskeleton organization"/>
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    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
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        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043592">
        <property type="entry name" value="FMNL_animal"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014768">
        <property type="entry name" value="GBD/FH3_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010473">
        <property type="entry name" value="GTPase-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45857">
        <property type="entry name" value="FORMIN-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45857:SF4">
        <property type="entry name" value="FORMIN-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06371">
        <property type="entry name" value="Drf_GBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01140">
        <property type="entry name" value="Drf_GBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101447">
        <property type="entry name" value="Formin homology 2 domain (FH2 domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51232">
        <property type="entry name" value="GBD_FH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GBD/FH3" evidence="3">
        <location>
            <begin position="399"/>
            <end position="866"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="196"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="283"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1013"/>
            <end position="1063"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="906"/>
            <end position="940"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="81"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="114"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="126"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="213"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="241"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="308"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="1023"/>
            <end position="1039"/>
        </location>
    </feature>
    <feature type="unsure residue" description="D or N" evidence="4">
        <location>
            <position position="279"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="1221"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51232"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OBZ85737.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="1221" mass="136967" checksum="2A48657EEF8A789B" modified="2016-11-30" version="1" fragment="single">MNTKQPLSTKNGSFDQPDNPPEVKLVRKSLSSPGSGIPTLVTKSELVTSSSSSSSHNDKKELQASIHSKNKKSNMNQSSNDRQLPRQSSTSSRFGKKNLLPTWLGGHTTIENNSQHSFASSSQASPELTNITIPPVNSSTSNLLSMSPTDDLLTEMSSTELDDAFEVLLDELNMRDIQREKLRQMPLERKLYLLQQSQQVKKSKNPTQQSRKSMMSTSTSNSSLLQPKILRPKQMKRSETSSRSLFSNTSNQSQKAQHRPSFQSSLRSKSLTSFLITNDHANMLTDPGPLLHGPDSQASSDKDEDNPHMQSSRTQIKASNPNDTKTPIPNKRAALYKFSRKTVENNRTKVGSMVLEFDALAHKSEDNSPDDSDAWLLLDNKTLSRQYLKYNTANRGVVAARPSVSSVFSSASVSPNKHLQSIKDPSQSNLSADKLALETTSREDELKRRDHSSPFYFVERLRSRNITIDALTKHLVSLQIVLLSGTVSWINEFLSRRHGGLIAIENVLEKLINKKFRKKEGSKLTELEELCLLECTKCLKALINTKPGLQQVLMRPVVLHQSLVILIACFMTTHQSLSSSVDESQLTIATNDTNISAQSLASTENMLLNESSSKKGLSKLESLKNEPLLESRTMTTTSYKISILIFEMFASLCITSPVTYNVIINVLSEVKGEQYRFERLIRCLQDLGIDKRACGNDFAQSMHMSEEQERQEKYEYAIAALNFFNSMIQAPNTAEERNSLRIELERRGYEDFTNSLYHIKESLPSRLEKQIANYIANKQMDLKKIECIESNKRQSILQLQPDDFAASALKTFHSEPDIYYLVVDSISELVKIGSDQIPLNKPFVQDIWRVIHLFIKSLASVKGNNDFHQALQQFIKSIQPIVGKISIENSENEIKEYSSSYTVPSSNNNLEDVEGLRNTVEELKEDLLKSQDSASKIRREKNELLIKMSKSLADIKDKDIHIINLEAEKRELLLKLHQFHRHTPSATTISRSISSNQLLSCTASQHVSKNVSFTLDSSSPSLSSPPSPPPPPPPPPLPPMMHVSGDVLRPSESGHPNSTNKKSRYLHPLALNLSFPSLKLLHEKTLPSVNTHDGYPIDSLNQLSSIPHIATKQFFWSKLPIDKIENTVWNEMLKLPISSPYLDNSSSISSSSSSSSSFYDAFDNDKEAEKHECQMIKLDTAELECLFKKSSKSITTSNTKPSILDNIRKQSAVILLDFNRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NA87</accession>
    <name>A0A1C7NA87_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein C6G9.01c</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_05929</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000336">
        <property type="protein sequence ID" value="OBZ86017.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NA87"/>
    <dbReference type="InParanoid" id="A0A1C7NA87"/>
    <dbReference type="OrthoDB" id="20835at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013885">
        <property type="entry name" value="DUF1764_euk"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34066:SF1">
        <property type="entry name" value="DUF1764 FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34066">
        <property type="entry name" value="GROWTH FACTOR 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08576">
        <property type="entry name" value="DUF1764"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="20"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="53"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="76"/>
            <end position="91"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ86017.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="172" mass="19013" checksum="AB02A6A8F6FCCB68" modified="2016-11-30" version="1">MAKQATDTKGKKDASKKKSTKDAGVKKATKETKSKTVVDEIDDIFSGKAKKSAPKEKEAEEKSTRKTKKATKKEESDSDSEDEEDQEELTEDQAQKVQEVVFAELAAVKSTKSNTKKRSAPPSTDEDFGDSRGLKKTNRTTEDGYPLYDVKELNIGNGLDTPECPFDCKCCF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NBE0</accession>
    <name>A0A1C7NBE0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Protein pob1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">pob1</name>
        <name evidence="10" type="ORF">A0J61_05502</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000298">
        <property type="protein sequence ID" value="OBZ86445.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NBE0"/>
    <dbReference type="FunCoup" id="A0A1C7NBE0">
        <property type="interactions" value="72"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NBE0"/>
    <dbReference type="InParanoid" id="A0A1C7NBE0"/>
    <dbReference type="OrthoDB" id="73680at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005769">
        <property type="term" value="C:early endosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055037">
        <property type="term" value="C:recycling endosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005802">
        <property type="term" value="C:trans-Golgi network"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005085">
        <property type="term" value="F:guanyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007032">
        <property type="term" value="P:endosome organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001881">
        <property type="term" value="P:receptor recycling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042147">
        <property type="term" value="P:retrograde transport, endosome to Golgi"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd09535">
        <property type="entry name" value="SAM_BOI-like_fungal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00174">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.29.30:FF:000286">
        <property type="entry name" value="PH-protein kinase domain containing protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.418.10">
        <property type="entry name" value="Calponin-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.40">
        <property type="entry name" value="SH3 Domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.50">
        <property type="entry name" value="Transcription Factor, Ets-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045188">
        <property type="entry name" value="Boi1/Boi2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001715">
        <property type="entry name" value="CH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036872">
        <property type="entry name" value="CH_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001849">
        <property type="entry name" value="PH_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001660">
        <property type="entry name" value="SAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013761">
        <property type="entry name" value="SAM/pointed_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036028">
        <property type="entry name" value="SH3-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001452">
        <property type="entry name" value="SH3_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22902:SF27">
        <property type="entry name" value="PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY A MEMBER 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22902">
        <property type="entry name" value="SESQUIPEDALIAN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00307">
        <property type="entry name" value="CH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00169">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07647">
        <property type="entry name" value="SAM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14604">
        <property type="entry name" value="SH3_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00033">
        <property type="entry name" value="CH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00233">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00454">
        <property type="entry name" value="SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00326">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47576">
        <property type="entry name" value="Calponin-homology domain, CH-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47769">
        <property type="entry name" value="SAM/Pointed domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50044">
        <property type="entry name" value="SH3-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50021">
        <property type="entry name" value="CH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50003">
        <property type="entry name" value="PH_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50105">
        <property type="entry name" value="SAM_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50002">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0344">Guanine-nucleotide releasing factor</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0728">SH3 domain</keyword>
    <feature type="domain" description="SH3" evidence="6">
        <location>
            <begin position="1"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="domain" description="SAM" evidence="9">
        <location>
            <begin position="174"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="domain" description="PH" evidence="7">
        <location>
            <begin position="435"/>
            <end position="531"/>
        </location>
    </feature>
    <feature type="domain" description="Calponin-homology (CH)" evidence="8">
        <location>
            <begin position="683"/>
            <end position="790"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="72"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="237"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="654"/>
            <end position="680"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="801"/>
            <end position="820"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="80"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="118"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="245"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="269"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="329"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="383"/>
            <end position="405"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022658"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50021"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50105"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OBZ86445.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="844" mass="95582" checksum="BC1C5A63B6F562F5" modified="2016-11-30" version="1">MSNIVYAIHDFKAENEDEIDFLVGEPITVLEKDEHYLDGWWQGINMHGQTGLFPMNYTSSEKPEQFYLDKPFQSHEDEPSSPQILEQQPQQSFELKPQQSFEQKPQPKELQQQDDTRQSYQMLHPHQQTSQNTSPGLSARSSRSTIEEEIDETISQLQVSSNNNDIRSTKTELWDVNQVAAWLKSVGLESAADNFVDQEITGDILLDLDADALKELGINTFGKRYKIMQAITSLKEGSPVENKPIPNSSVSTSAISRPESRKSIPASLRRSNSQSGPSIDTNESLYQHPRKAPLPPDTDNNHTAETGSILSHHLAPHSRPHTGIVRPLSPQSMTSSGISRSNTFNTVSTGGSYKSQENSIRKVLSRQSQQSVEKESITEWMAPSKSTSSTLSNTPTPSTSTSKKPLQISTTHKLSVSPLEEPTPVRTSTTEAFQAPEHEGWLHKQSDKYRTWNKRWFVLKGTNLFYFKSPKDVRMKGIINLRGYKIIVDSAIHAGKYCFKAQHERERTFYFYTDTEESMRAWLKMLMKTTIARDFRAPVMSSNQIATVSLDTARRMRPRPPSVIMYKNQKQMNTNNDLKMDMVQELDEMSERMPDTPPQDMTIPPPAPRLTEMFMHAREPSNYRASEQRIVPPELPKNYPNFDPPERIMSEEEEDLIDPQHRSLPIESSTSTASTLSNRSSREWSSEEYLDWVNSYLPPGKRVVDLSNAFRNGDALIQLLEAISGKEVRRPPAQKGGSMSALMLDNIVAAFKFMGREGVEVDGRYTLKDVFSANESKIIVMLEAIKVWADKNYPMSVSTNKDSYYSDESSSHSKKSDTSVLINENSGWRGSAMMDQLQGYQHSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NBV2</accession>
    <name>A0A1C7NBV2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Tubulin-specific chaperone B</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">F53F4.3</name>
        <name evidence="4" type="ORF">A0J61_05875</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000331">
        <property type="protein sequence ID" value="OBZ86076.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NBV2"/>
    <dbReference type="STRING" id="101091.A0A1C7NBV2"/>
    <dbReference type="InParanoid" id="A0A1C7NBV2"/>
    <dbReference type="OrthoDB" id="2130750at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd18186">
        <property type="entry name" value="BTB_POZ_ZBTB_KLHL-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.190">
        <property type="entry name" value="CAP Gly-rich-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000210">
        <property type="entry name" value="BTB/POZ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036859">
        <property type="entry name" value="CAP-Gly_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000938">
        <property type="entry name" value="CAP-Gly_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18916">
        <property type="entry name" value="DYNACTIN 1-RELATED MICROTUBULE-BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00651">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01302">
        <property type="entry name" value="CAP_GLY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00225">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01052">
        <property type="entry name" value="CAP_GLY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74924">
        <property type="entry name" value="Cap-Gly domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54695">
        <property type="entry name" value="POZ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50097">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00845">
        <property type="entry name" value="CAP_GLY_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50245">
        <property type="entry name" value="CAP_GLY_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BTB" evidence="2">
        <location>
            <begin position="96"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="domain" description="CAP-Gly" evidence="3">
        <location>
            <begin position="614"/>
            <end position="656"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="57"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="519"/>
            <end position="543"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OBZ86076.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="664" mass="75344" checksum="9B132961D9E0B831" modified="2016-11-30" version="1">MTTEKIYPDVRNGTLITFFPFHFPPFYFFSLLIFSTMDIHGPPNVFIRLKPQTIPVKRRHSKSDTTETIKRKKRHSRVSESSDEDESDQDIHWSCHTQILYNESPYFASLFGESFCDSKSNTTYLPAGIIDSTAFNNIVQYMYTQEVEKKESLQELCDMYSAADYLGMDQLCTLLTKRMTEFVHNCTCYCQTCVTSVPYLFPFCRTRTVELQDERMAAMTQKSIMILTGDPEKALPTYWITRHMAQLLIQLPQEISQALSQKVLHRVNKYNAIESLHACFAASSTLSTSDPLLSWSKPLHATLTSVQSRATRTIARHFDFFCCQYPALLSCIDGITYSFDFLEYLLLHVLEDQMDSDNVGILYKGIVYDLMSRHAVQYNDQAKHILNIAKVMILQYITRRIGDIKKHGGLDNLHEDMLKQLADDLDVRPKTLVHSKHPLFHRGIFSFLIPSIPNLTITSSSTHTNGLSRYSSHSTTHTARRVSIPGRSLNHTTTHTFSSSSSATFISHLAKLFKKFSDRSTSPTQSLSESRASRTLSAPTANTEVSTTSWSQIKVSQIKISQIQGRENGLFSFAKMKRKRSMKGQVSAPMIGMHRRVQLTRRPAPTVGTVMFVGHVSFGEGVWVGVELDRRVGKNDGSVDGIRYFTCSPNRGVFVRPEDVSIVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NBX0</accession>
    <name>A0A1C7NBX0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_05871</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000330">
        <property type="protein sequence ID" value="OBZ86086.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NBX0"/>
    <dbReference type="InParanoid" id="A0A1C7NBX0"/>
    <dbReference type="OrthoDB" id="2290418at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ86086.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="95" mass="10940" checksum="6574C5C19D2197E4" modified="2016-11-30" version="1">MTTDTCQSKASLYDSIPYLDSWYQTKDETYQVVPCVQPKKRKTCNAVSFSTAPPAVYCYQDKPTQEERPVALRRSSSEQVKGLIRFCTNKFSRRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NC38</accession>
    <name>A0A1C7NC38_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">1-acyl-sn-glycerol-3-phosphate acyltransferase</fullName>
            <ecNumber evidence="4">2.3.1.51</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">SLC1_0</name>
        <name evidence="7" type="ORF">A0J61_05265</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>a 1-acyl-sn-glycero-3-phosphate + an acyl-CoA = a 1,2-diacyl-sn-glycero-3-phosphate + CoA</text>
            <dbReference type="Rhea" id="RHEA:19709"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57970"/>
            <dbReference type="ChEBI" id="CHEBI:58342"/>
            <dbReference type="ChEBI" id="CHEBI:58608"/>
            <dbReference type="EC" id="2.3.1.51"/>
        </reaction>
    </comment>
    <comment type="domain">
        <text evidence="4">The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.51" evidence="4"/>
    <dbReference type="EMBL" id="LUGH01000280">
        <property type="protein sequence ID" value="OBZ86682.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="FunCoup" id="A0A1C7NC38">
        <property type="interactions" value="255"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NC38"/>
    <dbReference type="InParanoid" id="A0A1C7NC38"/>
    <dbReference type="OrthoDB" id="202234at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003841">
        <property type="term" value="F:1-acylglycerol-3-phosphate O-acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006654">
        <property type="term" value="P:phosphatidic acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07989">
        <property type="entry name" value="LPLAT_AGPAT-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004552">
        <property type="entry name" value="AGP_acyltrans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002123">
        <property type="entry name" value="Plipid/glycerol_acylTrfase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00530">
        <property type="entry name" value="AGP_acyltrn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10434">
        <property type="entry name" value="1-ACYL-SN-GLYCEROL-3-PHOSPHATE ACYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10434:SF11">
        <property type="entry name" value="1-ACYL-SN-GLYCEROL-3-PHOSPHATE ACYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01553">
        <property type="entry name" value="Acyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00563">
        <property type="entry name" value="PlsC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69593">
        <property type="entry name" value="Glycerol-3-phosphate (1)-acyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4 7" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="4" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="4" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0594">Phospholipid biosynthesis</keyword>
    <keyword evidence="4" id="KW-1208">Phospholipid metabolism</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4 7" id="KW-0808">Transferase</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="37"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="domain" description="Phospholipid/glycerol acyltransferase" evidence="6">
        <location>
            <begin position="100"/>
            <end position="217"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008655"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU361267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OBZ86682.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="278" mass="31495" checksum="4291119D27899121" modified="2016-11-30" version="1">MKEEASFALSWPVITISILSFLVVYRNYGGFFYRNFVNLLCFVTMAVYGTIIALVLPLFGKRDLINWSVARGYYYLGGFFTGVHVEVEGEENLHQHEGPAIYVCNHQSSLDIMLMGKVYPKNTAIIAKKQLKYVPFLGMFVRLNNTILLDRKNRESAVKEARKAAEDIQKKNTNVWVFPEGTRGHESEVTLLPXKKGPFYMAVQAHVPIIPVVLSNYTDLYSAKQKRFNSGVVRCRVLPAISTEGVEETSADIEKLATECREQMLTALKEITIKDKSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NCJ5</accession>
    <name>A0A1C7NCJ5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Rab guanine nucleotide exchange factor SEC2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">SEC2</name>
        <name evidence="5" type="ORF">A0J61_06873</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000436">
        <property type="protein sequence ID" value="OBZ85074.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NCJ5"/>
    <dbReference type="FunCoup" id="A0A1C7NCJ5">
        <property type="interactions" value="7"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NCJ5"/>
    <dbReference type="InParanoid" id="A0A1C7NCJ5"/>
    <dbReference type="OrthoDB" id="5560525at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051286">
        <property type="term" value="C:cell tip"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070319">
        <property type="term" value="C:Golgi to plasma membrane transport vesicle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005085">
        <property type="term" value="F:guanyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006887">
        <property type="term" value="P:exocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd21044">
        <property type="entry name" value="Rab11BD_RAB3IP_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.910">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040351">
        <property type="entry name" value="RAB3IL/RAB3IP/Sec2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009449">
        <property type="entry name" value="Sec2_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14430">
        <property type="entry name" value="RABIN3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14430:SF0">
        <property type="entry name" value="SEC2P DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25555">
        <property type="entry name" value="RAB3A-like_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06428">
        <property type="entry name" value="Sec2p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144284">
        <property type="entry name" value="Sec2 N-terminal region"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GDP/GTP exchange factor Sec2 N-terminal" evidence="4">
        <location>
            <begin position="119"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="34"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="261"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="583"/>
            <end position="667"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="106"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="44"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="591"/>
            <end position="603"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="628"/>
            <end position="647"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="657"/>
            <end position="667"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF06428"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OBZ85074.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="667" mass="75258" checksum="E7099942354148AF" modified="2016-11-30" version="1">MSAQNKEEVKPIDKQVTTKDIANLYSHLQTMIDNVPKSPRYKQPSPDLPLTPTASSSSLNIASPTTSTSKSLPTRSAKEPDCPCHHILVSKDSQHCALCDDVIPILAEIQDDREKKRNEIEEIKSLLKKEQVEAEQQQKKVIVLTKKEKELSEKIKATVEQYKSLQKDLVVLEKKYEFEKTEAEKAKKDKAAVENELEDLSQRLFEEANGMVANEKREKHQLEIQYRHLQEELKLCREQVEAEELQLRELKQKMCAMEEAREKSNSVSNLANSSTTSLEDSLLEDDPVHAQRASRDMSGLFTHEDNTVEVQETTDPMAINEFKAFFQLDQSIPIRKLHSATSFMKCSLTEDVEPCLRFGPNSRLSPKKLYEAILLNTCFIEETPYGFAIEQAKRPYDMPLRISASKNMIWERLSSAPVAVFTGCQACGRVTKDLPYRFRISMVDDWACIDRYCRDRLVAVCEFYTFIRNIRQGYYNGRTLNDLYGENIRLKLQMFYARMGTLSQTLQNMGIKGDTIGHASPPNMVIPPPISESETDTPAVVPVDGNTAAATNTTNAIDNNNENDIHTMDDHASIEAYTDKHTASIDDDKASVTSSQAESNISHKISDDEEEEPKTASTHPENAEESESTSVHSQDSNEPKNTSVQSKNAEEPKTASVHPQNASWADL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NCN3</accession>
    <name>A0A1C7NCN3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Malic enzyme</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">malA_0</name>
        <name evidence="12" type="ORF">A0J61_05241</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <cofactor evidence="7">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <text evidence="7">Divalent metal cations. Prefers magnesium or manganese.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the malic enzymes family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000278">
        <property type="protein sequence ID" value="OBZ86710.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NCN3"/>
    <dbReference type="STRING" id="101091.A0A1C7NCN3"/>
    <dbReference type="InParanoid" id="A0A1C7NCN3"/>
    <dbReference type="OrthoDB" id="5365701at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004471">
        <property type="term" value="F:malate dehydrogenase (decarboxylating) (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006108">
        <property type="term" value="P:malate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000182">
        <property type="entry name" value="NAD-dependent malic enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10380">
        <property type="entry name" value="Malic enzyme, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046346">
        <property type="entry name" value="Aminoacid_DH-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015884">
        <property type="entry name" value="Malic_enzyme_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012301">
        <property type="entry name" value="Malic_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037062">
        <property type="entry name" value="Malic_N_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012302">
        <property type="entry name" value="Malic_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001891">
        <property type="entry name" value="Malic_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF010052">
        <property type="entry name" value="PRK13529.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23406">
        <property type="entry name" value="MALIC ENZYME-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23406:SF32">
        <property type="entry name" value="NADP-DEPENDENT MALIC ENZYME"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00390">
        <property type="entry name" value="malic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03949">
        <property type="entry name" value="Malic_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000106">
        <property type="entry name" value="ME"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00072">
        <property type="entry name" value="MALOXRDTASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM01274">
        <property type="entry name" value="malic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00919">
        <property type="entry name" value="Malic_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53223">
        <property type="entry name" value="Aminoacid dehydrogenase-like, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00331">
        <property type="entry name" value="MALIC_ENZYMES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Malic enzyme N-terminal" evidence="11">
        <location>
            <begin position="71"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="domain" description="Malic enzyme NAD-binding" evidence="10">
        <location>
            <begin position="270"/>
            <end position="531"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="5">
        <location>
            <position position="94"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="5">
        <location>
            <position position="174"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="156"/>
        </location>
        <ligand>
            <name>(S)-malate</name>
            <dbReference type="ChEBI" id="CHEBI:15589"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="245"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="246"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="269"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="417"/>
        </location>
        <ligand>
            <name>(S)-malate</name>
            <dbReference type="ChEBI" id="CHEBI:15589"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="463"/>
        </location>
        <ligand>
            <name>(S)-malate</name>
            <dbReference type="ChEBI" id="CHEBI:15589"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008785"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR000106-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR000106-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR000106-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003426"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM00919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM01274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="OBZ86710.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="531" mass="58836" checksum="E2E6164BA8E993F3" modified="2016-11-30" version="1">MPSSTTESSNQISSYENEGTAIQHPKRKALHLTGLLPTGIETMDVQRRRALKQIHSKSTMLEKYIFLAQLRSSNVRLFYKIIMDDLQEFAPIIYTPTVGTACMEYSNIYPFLASPGVPDGLYLNSTDLDGLREAILNYRPVPDFSPEIAVITDGSRILGLGDLGSNGIGISIGKLQLYVAGAGIDPRKTLPIVLDLGTNNEKLRQDEFYLGLRKPRPSDDEFYDIVDTVLQTIHSIYPQLIIQFEDWSSEHAFGLLEKYKRKLVCFNDDIQGTGAVILSGVINAIRRVQIEADVAPHEHRIVFYGAGSAAIGVARQIQDYFQCELGLSEEQAKQLFWIVDSKGLVTIDRGDKLAQHKIYYARHDNNSQQFKNLIDIVDYVKPTALIGLSSSAGAFTEKVLKRLSELNKRPIVFPLSNPATQAECTFAEAMEATENRVIFASGTAFPSYTIPNTGEVCIPGQGNNMYIFPGLGLGSVLSKTRSISDSMVYHASVALADSLTEQERSQGWLYPSLTRIREVSATVATAIFELM</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NCR0</accession>
    <name>A0A1C7NCR0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Transcription factor SPT8</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">SPT8</name>
        <name evidence="4" type="ORF">A0J61_05075</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000264">
        <property type="protein sequence ID" value="OBZ86871.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NCR0"/>
    <dbReference type="FunCoup" id="A0A1C7NCR0">
        <property type="interactions" value="52"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NCR0"/>
    <dbReference type="InParanoid" id="A0A1C7NCR0"/>
    <dbReference type="OrthoDB" id="10260946at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000124">
        <property type="term" value="C:SAGA complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005669">
        <property type="term" value="C:transcription factor TFIID complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016251">
        <property type="term" value="F:RNA polymerase II general transcription initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017025">
        <property type="term" value="F:TBP-class protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003712">
        <property type="term" value="F:transcription coregulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006325">
        <property type="term" value="P:chromatin organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000122">
        <property type="term" value="P:negative regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:1900237">
        <property type="term" value="P:positive regulation of induction of conjugation with cellular fusion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006367">
        <property type="term" value="P:transcription initiation at RNA polymerase II promoter"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057544">
        <property type="entry name" value="Beta-prop_SPT8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19879:SF1">
        <property type="entry name" value="CANNONBALL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19879">
        <property type="entry name" value="TRANSCRIPTION INITIATION FACTOR TFIID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23798">
        <property type="entry name" value="Beta-prop_SPT8"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="Transcription factor spt8 beta-propeller" evidence="3">
        <location>
            <begin position="65"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="1">
        <location>
            <begin position="72"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="1">
        <location>
            <begin position="209"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="domain" description="Transcription factor spt8 beta-propeller" evidence="3">
        <location>
            <begin position="282"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="143"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="21"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="31"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="153"/>
            <end position="164"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF23798"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OBZ86871.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="466" mass="51996" checksum="E0014E86EDF49434" modified="2016-11-30" version="1">MSSDEEDIDLNDEATSQMTDDAGDLMEVEDQSASIQNSPPSLENLPETRQLNLKIDPQLLTCKAYDCVPLAAVLHPSPIFSLATTICYRWVLTGSEDGYIRKWDFFASMNGKSSLTQAQRHHYVDSVVHSGILSSWWENEEVPEQVKQETPEDSIQPTRSNTAHQEPKLSPVYSLAVHSEALWALQGCENGTINLTTVRHEEGKCHHVLRKHTGPVSVLVITPDETGAISGSWDKSVVEWDLNTGSIVRSYDGHNTQISSAEFQPIYTPQGSLDALYWNKKNPNTLLTTSVDGQCLLWDRREPEQAARRLPLPEKTPPWCLSATWNTDGSKIYIGRRNGTVDEYDYASQKWIQSFRMPANSGPVSCVKSMPNGKHIICASNDNIRIWDTTLESNFTVKPDTEQGFHQPSKLSSVIPFHILPGHHGGTISHISIDPTCKYMITTSGNRGWDGVSTNACLFYEIVNKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NCS4</accession>
    <name>A0A1C7NCS4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_06785</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000426">
        <property type="protein sequence ID" value="OBZ85164.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NCS4"/>
    <dbReference type="STRING" id="101091.A0A1C7NCS4"/>
    <dbReference type="InParanoid" id="A0A1C7NCS4"/>
    <dbReference type="OrthoDB" id="2158884at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="170"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="225"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="277"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="357"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="236"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="277"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="366"/>
            <end position="378"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ85164.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="395" mass="45032" checksum="A7558C5CEEAA1E24" modified="2016-11-30" version="1">MMTASTISSLDGGGEWKEGVKLAYKIGFKFPQRRSADVALKHPFFSESDENVVPMECEPITPPTTVDRHLASSYGRAPKDITPFDLLTTPQVPYQICPDWNIDHPISRHGRLSSCTTHVDKFLHDVDGADANPWLPQTRPIYSSHQKVHPVTDRPNSSQHHYHHQNRYSYGAHHSHRPSTPVVEHKKNIPTSSHTPSKRHSVRHEEEELPRRTSSHLLHHLHHPHHNDYHQQHRPSNGSSGGSNSASFGLDRVPHYGNQLIKWAPCRFTIPMDKKEEGLVDKESRPESRQCRTPGPFSSSLIHGKYASTTTVSSPTSFISNSAIRPWTPPSSQSTSREKTSYYEEHQQIWMHKSETHHATVHHRVDKYTNEGKKKDQENGDDENDCSNKRYICVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7ND05</accession>
    <name>A0A1C7ND05_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="8">E3 ubiquitin-protein ligase RNF13</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">RNF13</name>
        <name evidence="8" type="ORF">A0J61_05109</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000267">
        <property type="protein sequence ID" value="OBZ86840.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7ND05"/>
    <dbReference type="STRING" id="101091.A0A1C7ND05"/>
    <dbReference type="InParanoid" id="A0A1C7ND05"/>
    <dbReference type="OrthoDB" id="8062037at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006511">
        <property type="term" value="P:ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd16454">
        <property type="entry name" value="RING-H2_PA-TM-RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051826">
        <property type="entry name" value="E3_ubiquitin-ligase_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046450">
        <property type="entry name" value="PA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003137">
        <property type="entry name" value="PA_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22765:SF416">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE GODZILLA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22765">
        <property type="entry name" value="RING FINGER AND PROTEASE ASSOCIATED DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02225">
        <property type="entry name" value="PA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13639">
        <property type="entry name" value="zf-RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52025">
        <property type="entry name" value="PA domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="5" id="KW-0863">Zinc-finger</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="176"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="domain" description="RING-type" evidence="7">
        <location>
            <begin position="313"/>
            <end position="355"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OBZ86840.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="508" mass="56187" checksum="C836D57625A88BB0" modified="2016-11-30" version="1">MMIYSNGTAVDFENVYLKPREFKSGIVPFDNLTQPPSSGLEGILYDRGYSCQPDASFGFKRPDLLNMSSKIALVKKGGGCSFYQKVYLSELDGASGVIIFDDIAFRDDDNSGSMKITKGNITISMYYVDLNIGQELTNMLQYVAAYPISNTSDNATTFQPVISLTMHPAVGGFPSAWEFTLIIVVALLAISFLASVGMHWHLWRIRRRQRAIFENGLLDINAATVMPQPQKKTIEPASLALFPTRIIGDEPLPPSIDEVTSITLPSLTRVESARSERSSKAIENAELLLSATIPVATPHSSLPEQPSAVSDACVICLDEFALGEQVRKLPCGHEYHCECIDPWLTIKSASCPLCKYDCSLNIPKSQEQEETLAGETSTPPPPSYRSNPFFSTISSFRSRQNGSPFSMSSSSAFGPTIHADQAEEFSRSWMARSLPRNMRRQIEAVAAANRESVIELPARMTQQPSVHTPLTDEWQDNTISRRLGRKLIRTLPRLGNLDHRSHGSRDPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NDE0</accession>
    <name>A0A1C7NDE0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Plasma membrane proteolipid 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">pmp3</name>
        <name evidence="8" type="ORF">A0J61_04838</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the UPF0057 (PMP3) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000246">
        <property type="protein sequence ID" value="OBZ87107.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NDE0"/>
    <dbReference type="STRING" id="101091.A0A1C7NDE0"/>
    <dbReference type="InParanoid" id="A0A1C7NDE0"/>
    <dbReference type="OrthoDB" id="2802411at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000612">
        <property type="entry name" value="PMP3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21659">
        <property type="entry name" value="HYDROPHOBIC PROTEIN RCI2 LOW TEMPERATURE AND SALT RESPONSIVE PROTEIN LTI6 -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21659:SF42">
        <property type="entry name" value="UPF0057 MEMBRANE PROTEIN ZK632.10-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01679">
        <property type="entry name" value="Pmp3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008889634" evidence="7">
        <location>
            <begin position="25"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="33"/>
            <end position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009530"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OBZ87107.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="92" mass="9994" checksum="8A83E56097C9C24C" modified="2016-11-30" version="1">MSPYTGRDIALFIVAFFFPPASVAIKTGCSADLLINICLCALGAIPGIIHGFYIVHKHNENLEDIETGGLRYERVPVEDPSRVTYGTTAPNN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NDH4</accession>
    <name>A0A1C7NDH4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">ACAP2</name>
        <name evidence="9" type="ORF">A0J61_04815</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000243">
        <property type="protein sequence ID" value="OBZ87135.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NDH4"/>
    <dbReference type="STRING" id="101091.A0A1C7NDH4"/>
    <dbReference type="InParanoid" id="A0A1C7NDH4"/>
    <dbReference type="OrthoDB" id="10266696at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd13250">
        <property type="entry name" value="PH_ACAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.220.150:FF:000009">
        <property type="entry name" value="stromal membrane-associated protein 1 isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.220.150">
        <property type="entry name" value="Arf GTPase activating protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.60">
        <property type="entry name" value="Arfaptin homology (AH) domain/BAR domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045258">
        <property type="entry name" value="ACAP1/2/3-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027267">
        <property type="entry name" value="AH/BAR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037278">
        <property type="entry name" value="ARFGAP/RecO"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001164">
        <property type="entry name" value="ArfGAP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038508">
        <property type="entry name" value="ArfGAP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004148">
        <property type="entry name" value="BAR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001849">
        <property type="entry name" value="PH_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23180:SF160">
        <property type="entry name" value="ADP-RIBOSYLATION FACTOR GTPASE-ACTIVATING PROTEIN EFFECTOR PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23180">
        <property type="entry name" value="CENTAURIN/ARF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01412">
        <property type="entry name" value="ArfGap"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16746">
        <property type="entry name" value="BAR_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00169">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00405">
        <property type="entry name" value="REVINTRACTNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00105">
        <property type="entry name" value="ArfGap"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00233">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57863">
        <property type="entry name" value="ArfGap/RecO-like zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103657">
        <property type="entry name" value="BAR/IMD domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50115">
        <property type="entry name" value="ARFGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50003">
        <property type="entry name" value="PH_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="1" id="KW-0343">GTPase activation</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 6" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="PH" evidence="7">
        <location>
            <begin position="262"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="domain" description="Arf-GAP" evidence="8">
        <location>
            <begin position="403"/>
            <end position="526"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="5">
        <location>
            <begin position="563"/>
            <end position="595"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="5">
        <location>
            <begin position="596"/>
            <end position="628"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022468"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50115"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OBZ87135.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="723" mass="83052" checksum="5595ED2C1C7E56FA" modified="2016-11-30" version="1">MPALDIRGCLEDSPTFRKRIQSHEESIHNFENSLKALIKLTRSQVDLSIAYSHQQTELAREFMDFAHAQDDPIVAQALEKFGKSVVEVEKSRHMFVMDTFISPLDHFLKNTIMPIKELRKRFEKSSDEVDSALSRYMSKKPKDPTLQESAKELADTRKIFHKSYMEYVSQLNDIEAKKKVDYMENVLAYMYTESAFHHQSYEILKDLEPYMRDLTGLLHDSRQRYEEEVEEGLMYQQTCGQNASDQYNPMQQPYTPVEVIPKAHKSGYLFERKNGRVYQSWLRKYFSIYDDELISTTRGSKISTKEEDGTHVYNLRVCSVKLTDGYDRRFCFEVISPNRVLVLQAENEQDMNEWIASIRTASQTALNSEDAPRYVQGSPNVRKSLFESQHKETNNDQDQEKQRESLRKIRMIPGNNQCADCKEKDPEWSCTNLGIIVCIECSGIHRSLGVHISKVRSVILDKWEPDAIEVMLRLGNSVGNGIYEAFVPKHMEPFRIDPSSNRNDRDLWIIEKYAKRSFVRQSNLDQSSLDKAFWEAVVKQDLPQALKRLAQGAHVDYGNPEEELRTALHKAVDGGDEVSVEFLLQRLSDIDQQDERGWTALHYAAANNNVRLVLALLKRHAKADIKDNADMTPLDLAVDRQSVQAVTALRLFAFDKQHNDSPASSLDFGFREAMSSFKHVNSERPPIGSSHSAIDLREADAMVSKSSGILLDDQNNQLLSIEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NDU7</accession>
    <name>A0A1C7NDU7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_04702</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000235">
        <property type="protein sequence ID" value="OBZ87255.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NDU7"/>
    <dbReference type="InParanoid" id="A0A1C7NDU7"/>
    <dbReference type="OrthoDB" id="42638at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ87255.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="88" mass="9919" checksum="6DF81E020A86E0F3" modified="2016-11-30" version="1">MTACVAFKHLNFPWKIEPHQCVVGSSFGEVEIPILKEFVINAKIGIVHLYLPTVIKGPFMMHYGMHPGQVNLITQDGRVLPAFRNFPT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NDV0</accession>
    <name>A0A1C7NDV0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">H15 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_04687</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000234">
        <property type="protein sequence ID" value="OBZ87265.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NDV0"/>
    <dbReference type="InParanoid" id="A0A1C7NDV0"/>
    <dbReference type="OrthoDB" id="2208992at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ87265.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="90" mass="10398" checksum="68E060062D229281" modified="2016-11-30" version="1">MSAPTHSAGKLVKHLIAKNGPMTTQTLFNYVPTYPQQFISKTHLKQKVLKSLEGEGVLFKKVNREKTQPKPVWEWQFVDPKLAEKYKDLM</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-06-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NE15</accession>
    <name>A0A1C7NE15_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_06347</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000379">
        <property type="protein sequence ID" value="OBZ85604.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NE15"/>
    <dbReference type="InParanoid" id="A0A1C7NE15"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ85604.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="89" mass="9943" checksum="8C89A55B3FCE126B" modified="2016-11-30" version="1">MVFSYLLSGEFYLVTGYKLGEICAVKVGRGGIESPCDAIPEISENLKRENSKLLMFLHSRRKKLDLAVTKFLGNSSDKMLKLVIMSSLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NE42</accession>
    <name>A0A1C7NE42_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">peptide-methionine (S)-S-oxide reductase</fullName>
            <ecNumber evidence="2">1.8.4.11</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">Peptide-methionine (S)-S-oxide reductase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">mxr1_0</name>
        <name evidence="8" type="ORF">A0J61_05137</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>L-methionyl-[protein] + [thioredoxin]-disulfide + H2O = L-methionyl-(S)-S-oxide-[protein] + [thioredoxin]-dithiol</text>
            <dbReference type="Rhea" id="RHEA:14217"/>
            <dbReference type="Rhea" id="RHEA-COMP:10698"/>
            <dbReference type="Rhea" id="RHEA-COMP:10700"/>
            <dbReference type="Rhea" id="RHEA-COMP:12313"/>
            <dbReference type="Rhea" id="RHEA-COMP:12315"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:16044"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:44120"/>
            <dbReference type="ChEBI" id="CHEBI:50058"/>
            <dbReference type="EC" id="1.8.4.11"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>[thioredoxin]-disulfide + L-methionine + H2O = L-methionine (S)-S-oxide + [thioredoxin]-dithiol</text>
            <dbReference type="Rhea" id="RHEA:19993"/>
            <dbReference type="Rhea" id="RHEA-COMP:10698"/>
            <dbReference type="Rhea" id="RHEA-COMP:10700"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:50058"/>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
            <dbReference type="ChEBI" id="CHEBI:58772"/>
            <dbReference type="EC" id="1.8.4.11"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the MsrA Met sulfoxide reductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.8.4.11" evidence="2"/>
    <dbReference type="EMBL" id="LUGH01000270">
        <property type="protein sequence ID" value="OBZ86816.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NE42"/>
    <dbReference type="FunCoup" id="A0A1C7NE42">
        <property type="interactions" value="468"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NE42"/>
    <dbReference type="InParanoid" id="A0A1C7NE42"/>
    <dbReference type="OrthoDB" id="77405at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008113">
        <property type="term" value="F:peptide-methionine (S)-S-oxide reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034599">
        <property type="term" value="P:cellular response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1060.10:FF:000006">
        <property type="entry name" value="Peptide methionine sulfoxide reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1060.10">
        <property type="entry name" value="Peptide methionine sulphoxide reductase MsrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01401">
        <property type="entry name" value="MsrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002569">
        <property type="entry name" value="Met_Sox_Rdtase_MsrA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036509">
        <property type="entry name" value="Met_Sox_Rdtase_MsrA_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00401">
        <property type="entry name" value="msrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43774">
        <property type="entry name" value="PEPTIDE METHIONINE SULFOXIDE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43774:SF1">
        <property type="entry name" value="PEPTIDE METHIONINE SULFOXIDE REDUCTASE MSRA 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01625">
        <property type="entry name" value="PMSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55068">
        <property type="entry name" value="Peptide methionine sulfoxide reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptide methionine sulphoxide reductase MsrA" evidence="7">
        <location>
            <begin position="8"/>
            <end position="162"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005591"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00030643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00047806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00048782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01625"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OBZ86816.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="170" mass="19625" checksum="CA0E003E495E601A" modified="2016-11-30" version="1">MTIDALEKATFAAGCFWGVEHIFNKHFKELGIITKVGYMGGELEDPTYKQVKTGTTNHAEVCEILFDPSKVSFETLVEFFYKMHDPTTLNAQGPEDIGTQYRSAIFYHTDEQKSIAEKVTKEVQEKHYPETKIVTEISSAAKFYDAEEYHQFYLEKNPEGYACPTHYLRW</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NE87</accession>
    <name>A0A1C7NE87_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_04861</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000248">
        <property type="protein sequence ID" value="OBZ87089.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NE87"/>
    <dbReference type="InParanoid" id="A0A1C7NE87"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.60.10">
        <property type="entry name" value="Zinc finger, CCHC-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ87089.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="152" mass="17496" checksum="ED7A09FBE9A3B04C" modified="2016-11-30" version="1">MPAIRTCDSCNQEGHSRITSRLCPNNCRAATCTSCGNIDHRYTTHRDCPNNVANRMFFMLSLSYIVSKSNDNLSIYQKYIKSGCFWKVVDDIKSDIKLIEEKKNLETISKEIACRKGVDEGLEVILTQQLKLIKERRRLSSEYQMLQSFSCL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NEB2</accession>
    <name>A0A1C7NEB2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="15">Kinesin-like protein KIF21B</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="15" type="primary">Kif21b</name>
        <name evidence="15" type="ORF">A0J61_04514</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="11">Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000223">
        <property type="protein sequence ID" value="OBZ87431.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="FunCoup" id="A0A1C7NEB2">
        <property type="interactions" value="331"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NEB2"/>
    <dbReference type="InParanoid" id="A0A1C7NEB2"/>
    <dbReference type="OrthoDB" id="3176171at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005875">
        <property type="term" value="C:microtubule associated complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008017">
        <property type="term" value="F:microtubule binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003777">
        <property type="term" value="F:microtubule motor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007018">
        <property type="term" value="P:microtubule-based movement"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007052">
        <property type="term" value="P:mitotic spindle organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051231">
        <property type="term" value="P:spindle elongation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01372">
        <property type="entry name" value="KISc_KIF4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.850.10:FF:000011">
        <property type="entry name" value="Kinesin family member 21A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.850.10">
        <property type="entry name" value="Kinesin motor domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027640">
        <property type="entry name" value="Kinesin-like_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019821">
        <property type="entry name" value="Kinesin_motor_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001752">
        <property type="entry name" value="Kinesin_motor_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036961">
        <property type="entry name" value="Kinesin_motor_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47969">
        <property type="entry name" value="CHROMOSOME-ASSOCIATED KINESIN KIF4A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47969:SF15">
        <property type="entry name" value="CHROMOSOME-ASSOCIATED KINESIN KIF4A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25764">
        <property type="entry name" value="KIF21A_4th"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00225">
        <property type="entry name" value="Kinesin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00380">
        <property type="entry name" value="KINESINHEAVY"/>
    </dbReference>
    <dbReference type="SMART" id="SM00129">
        <property type="entry name" value="KISc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00411">
        <property type="entry name" value="KINESIN_MOTOR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50067">
        <property type="entry name" value="KINESIN_MOTOR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8 12" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="10" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="4" id="KW-0493">Microtubule</keyword>
    <keyword evidence="9 11" id="KW-0505">Motor protein</keyword>
    <keyword evidence="6 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="Kinesin motor" evidence="14">
        <location>
            <begin position="5"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="542"/>
            <end position="616"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="683"/>
            <end position="705"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="729"/>
            <end position="763"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1143"/>
            <end position="1166"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1327"/>
            <end position="1378"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1467"/>
            <end position="1525"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1539"/>
            <end position="1558"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1591"/>
            <end position="1651"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="12">
        <location>
            <begin position="371"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="12">
        <location>
            <begin position="489"/>
            <end position="516"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="12">
        <location>
            <begin position="808"/>
            <end position="961"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="542"/>
            <end position="551"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="13">
        <location>
            <begin position="552"/>
            <end position="562"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="563"/>
            <end position="573"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="581"/>
            <end position="594"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="13">
        <location>
            <begin position="595"/>
            <end position="606"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="690"/>
            <end position="700"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="743"/>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="1149"/>
            <end position="1160"/>
        </location>
    </feature>
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        <location>
            <begin position="1365"/>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="1479"/>
            <end position="1506"/>
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    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="1515"/>
            <end position="1525"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="1541"/>
            <end position="1558"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="1605"/>
            <end position="1616"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="1627"/>
            <end position="1637"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="84"/>
            <end position="91"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00283"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50067"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="OBZ87431.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="1651" mass="185674" checksum="751699FFBB8EEB6A" modified="2016-11-30" version="1">MTSTAVRVGLRVRPLTQKEQIENCTECISFIPNEPQILVGTDKSFTYDYVFSNESHQQQVYEQAAKPLLDKFLEGFNATILAYGQTGSGKTYSMGTGLESTVNPEHEGIVPRCIVDLFRNLKERSESNPDFTYEVFVSFLELYNEELIDLLSPQQQQISAAAKRKSGSGLPPPVAPVEVTIREDIAGNIYWSGVREEPCSNPEELLSFLAKGSLCRTVGSTEMNTVSSRSHAVFSVILKQQKSPEEASLTSKFHFVDLAGSERLKRTNAQGDRAREGISINSGLLALGNVISALGDEARRISHIPYRDSKLTRLLQDSLGGNSQTLMLACVSPADSNFMETLNTLKYANRARNIKNKVTINQDFAGSSIEVNQLRAQLARLRIELASLRAESAGTEKGRSNNSFNSFQHDEEVRALRSEVTRLRDRVQDLSTNLIQVTSERDTMLIERELGEFMTQADDSSLTTSNSNTYIVDGDASVAQKSVKTHPIIAQYQKTIADLTNELSDTQARLSFLENTKAAGMNAMSMGNSTSISFSGKTTSFYKPEQSVSTRRSSKTNRRGRKSANSSTGTSANTKHKVSRRAPALSLSQSSSSKTSRKRRNNRSKHYQGDVDSEEDEAYANDNLLNENEIKQSIAKAKEEILKGMEVLDLIKPMEDAAQSWEDELEAFEKAEKEMYEKVNQIERIESDEGNYSASSSPTDDNQRHENDLDLMMEIEALSVPCWDHKSTTTYAKKPPQADDNTETSSASYTSMTSSASSKPTADAAILQTEKQNPQLVRMLHQIQSDIRVKEELVSHLEKSETKYCFMRRKFDEKVSELHNRLAELQKEKDKALAKTKSSFSSVPNRNDMSIQIKEKQQVLETRQLYENKMKQLVMEIHELKRNYTRTINNLQSTRSQHESLLKSLRVNVETLKLEKKRMIKRMKQETERVREQMAKQERKISKLQRQHSEISHARTKLEKEHEAQKLTLKRRDKEILINNSQLKQLIDILKKAVREGGMLDDQLLGKVSHIVGGNFAAVARRGGMRNLPGYRQSRKKKNPIPVHVRVARKKELLDKMLYQFIQGKQAIVEMEQLLFRRERLASEKMELLEERKSIFMAEKEAADMTGEPMDMLAIDLADERIDLLEAEISYLSARIRALQSEASGEANDASTYGGTMERQQSQEKRKVTFADDIVTNPPASEEWTDMDALEEQFNISPNAAPELVYDATIKLLKTLEADECRSITEALVDDITNARMSECNRQITMQNLEKSVQDLRRTLIVMKRAAIATTVENERRIRKLEEKDKGVNNSGGHLDDKIEDYIMNSGNTIFDKIYEDGLRGMITTPEPEYMINDSTDDLSSSSSTYERRSSTHSEGLIPPPSPLTLPTYTNNPSTLTNNLMLSPTRPPTSSGIRAPVSLTEKGGVMRVNNSNYPTRDTTPSPDRFYNMIQKRLSWQQRAGGSESPIPMIMANPAEFARYAMDRESSTSSIHSGHLRRASLQSDYSSSQNSSSWNNSGPPTVSSSQSSRKRAFSVQQPAAQPQLLQQQLNRRRASLRELSMKGSNSTVPMGAQSPSSSTYMSEYDYEVSATLQRANSLPPKRAPAVSMSNLERVSTPTGGNVFRRLSQTPTRASQAKVSHRHSSSSMDELRLRWEQQEQRSSSAMSGSYYGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NEC4</accession>
    <name>A0A1C7NEC4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Sorting nexin-41</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">SNX41_0</name>
        <name evidence="10" type="ORF">A0J61_04508</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endosome membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the sorting nexin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000222">
        <property type="protein sequence ID" value="OBZ87445.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NEC4"/>
    <dbReference type="FunCoup" id="A0A1C7NEC4">
        <property type="interactions" value="51"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NEC4"/>
    <dbReference type="InParanoid" id="A0A1C7NEC4"/>
    <dbReference type="OrthoDB" id="289314at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010008">
        <property type="term" value="C:endosome membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035091">
        <property type="term" value="F:phosphatidylinositol binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006914">
        <property type="term" value="P:autophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042147">
        <property type="term" value="P:retrograde transport, endosome to Golgi"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06867">
        <property type="entry name" value="PX_SNX41_42"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.60">
        <property type="entry name" value="Arfaptin homology (AH) domain/BAR domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1520.10">
        <property type="entry name" value="Phox-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027267">
        <property type="entry name" value="AH/BAR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001683">
        <property type="entry name" value="PX_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036871">
        <property type="entry name" value="PX_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044106">
        <property type="entry name" value="PX_Snx41/Atg20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051079">
        <property type="entry name" value="Sorting_Nexin_Autophagy"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46979">
        <property type="entry name" value="SORTING NEXIN-41"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46979:SF2">
        <property type="entry name" value="SORTING NEXIN-41"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00787">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00312">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103657">
        <property type="entry name" value="BAR/IMD domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64268">
        <property type="entry name" value="PX domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50195">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0072">Autophagy</keyword>
    <keyword evidence="4" id="KW-0967">Endosome</keyword>
    <keyword evidence="7" id="KW-0446">Lipid-binding</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0653">Protein transport</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="PX" evidence="9">
        <location>
            <begin position="23"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022753"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OBZ87445.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="473" mass="53718" checksum="2C8FA57C3E7B9A20" modified="2016-11-30" version="1">MSHRNSFVKSGCGCSVERVLIQDESYIFITGAQKQSDSPSGKAYFAYHIRIGDIETKRRYSEFESLRKAFTLLYPALIVPPIPEKHSLVDYAALSTRVKDDLPMVEKRKRMLQTFLNRVAKHPELGREHVFHRFLESTTIWSDVLHSPPLSTLPKNPLQMIVSKQLDLPTHTYHPVLGSNLVPSPSAAYQLKKPDPRFEESEKFTFRIANYMSNHLDKSQRKVIRRLGELANDYAELGAVYNGFSLNETGAVANAIEKIGQAVDASYTETGQMVTSLEGEFAEPIQEHAQFAQIIKQVLKFRHMKHAQVELIEGSLESKRHHLDSLLRMEGEARRLEEAMSQSNDTTFVEESPSSYVSRQSNPSWTGGPMKVISAVGHTLQTMIDVNPEATRRNQIGMSKDAMGVLQEALDVSSKDLNAISLQLQNDLDRFQTEKIQDMRDMLIAYAKIHIRYCQQNLESWQEARAEVEKIPI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NER6</accession>
    <name>A0A1C7NER6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">DnaJ subfamily C member 21</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">DNAJC21</name>
        <name evidence="7" type="ORF">A0J61_04356</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000211">
        <property type="protein sequence ID" value="OBZ87602.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NER6"/>
    <dbReference type="FunCoup" id="A0A1C7NER6">
        <property type="interactions" value="702"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NER6"/>
    <dbReference type="InParanoid" id="A0A1C7NER6"/>
    <dbReference type="OrthoDB" id="5894at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.110:FF:000046">
        <property type="entry name" value="dnaJ homolog subfamily C member 21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051964">
        <property type="entry name" value="Chaperone_stress_response"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018253">
        <property type="entry name" value="DnaJ_domain_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003604">
        <property type="entry name" value="Matrin/U1-like-C_Znf_C2H2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022755">
        <property type="entry name" value="Znf_C2H2_jaz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054076">
        <property type="entry name" value="ZUO1-like_ZHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44029">
        <property type="entry name" value="DNAJ HOMOLOG SUBFAMILY C MEMBER 21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44029:SF1">
        <property type="entry name" value="DNAJ HOMOLOG SUBFAMILY C MEMBER 21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12171">
        <property type="entry name" value="zf-C2H2_jaz"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21884">
        <property type="entry name" value="ZUO1-like_ZHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00625">
        <property type="entry name" value="JDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00451">
        <property type="entry name" value="ZnF_U1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00636">
        <property type="entry name" value="DNAJ_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="J" evidence="6">
        <location>
            <begin position="4"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="383"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="419"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="498"/>
            <end position="519"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="242"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="383"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="455"/>
            <end position="466"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OBZ87602.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="519" mass="60257" checksum="E88011629DDB995C" modified="2016-11-30" version="1">MRICYYDLLGVERQATSTDIKKAYRKQALIWHPDKNGDRIQEATERFAMIHEAYEVLSDPQERSWYDGHRDSILRGDDHSGQRDSSAGTTAEDLMRYFSVSEFKGYEDTTKGFYNVYRSLFERLANEEEEAFRNNPAEDEDEVRSTATFYPSFGNASTLFIVPNDYGVKDFYGAWSNFSTLKSFAWMDKWRLSDAPNRYVRRQMEKENKKARETGRKEYNDTVRSLAEFLRKRDPRVKEYLAEEQKRKEAAAAENKARMLREKQELQAKVAEYQVPEWAQVEEEELDEDENASEEELEEEISEFYCVVCDKAYKSERQFKSHELSKRHIDNLELLREEMLKDDAHFDFDNQDELDAGIPLDTDELSQTLDDLELNEEIPVVKDKKKKKKNKAKTPHWGFDEDTVPDDLDEVSALAAALEEEKSRRRRKGHGKAALSDDESAPASPPDETVEKMSAKTKREKRKEKKKLKEETVGSPETACNVCTEQFETRNQLFAHIKETGHALASEQGGKGGKKGKRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NFX6</accession>
    <name>A0A1C7NFX6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Squamous cell carcinoma antigen recognized by T-cells 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">sart3</name>
        <name evidence="8" type="ORF">A0J61_03911</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000179">
        <property type="protein sequence ID" value="OBZ88051.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NFX6"/>
    <dbReference type="STRING" id="101091.A0A1C7NFX6"/>
    <dbReference type="InParanoid" id="A0A1C7NFX6"/>
    <dbReference type="OrthoDB" id="360390at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008380">
        <property type="term" value="P:RNA splicing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003107">
        <property type="entry name" value="HAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008847">
        <property type="entry name" value="Suf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17204">
        <property type="entry name" value="PRE-MRNA PROCESSING PROTEIN PRP39-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17204:SF25">
        <property type="entry name" value="RRM DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05843">
        <property type="entry name" value="Suf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00386">
        <property type="entry name" value="HAT"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="4" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Suppressor of forked" evidence="7">
        <location>
            <begin position="42"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="537"/>
            <end position="731"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="545"/>
            <end position="560"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="561"/>
            <end position="579"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="637"/>
            <end position="665"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="675"/>
            <end position="688"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="697"/>
            <end position="724"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF05843"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OBZ88051.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="731" mass="85940" checksum="10842134D50C84B8" modified="2016-11-30" version="1">MDQISDKIVSDATEQQVDDIVKDEPIDEANDTLNALEAIPDVIEKLDEDNTQYDLHVRLIQLLRRAELYDQLEQARINMHAIYPMSEALWLEWIQDAKKEADTVEGKKKLFQLYDLAQEDYVYYTEYILENFYEDFTDNITTLDESVEDWIDHTRQDLLKAVRASSNHVKQSQEIWKLYSEFELAVLGRFNEDEYQLSRTKKMYLDRLAVLHIDCEDTFNSYSQFVTQYSNTNYEESMLEANKIYAKTKAAAEERDYYELQLTSTGYALDTFYQYIEYELTTKNMFALNHVRSLYERAIIYYCTDPSLWDDYILFLIERARIQAYLETTCKRAVRNCPWSGVLWAHLARAFESGQKSVEQVQNIFDRALASKPILSSIEDLVTVLLAKCDHARRRIDWEDLDEDAVMDLKVAFEESLEYIAEAFPESGDPYYRIEKYYAYISLKRFDDAEKARELWEDVVERQGLNTEAWIQLILFERDQENYERCATLFKQAIQKKIDNPARLIDVWNTIEHEVGTLASFEESLVRINRKTKQLSRQWQSQYTQEKEEKSKEKSKEKKTMDRKKKSQHRIAQKQRAREKKNQSDFKAPIQKALQSQHHQKPVEKEEPVFAADYESTKEDISTEVASKEPNPLKRKLSAENEQEAKKVKSGPKEEQEEAKQDKPKSTAAFMPRPRSARPHTAIRRGKALKLGQRSVNRNDADKLMTESDKKEEPETSKSNDDFRAMLLGKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NG22</accession>
    <name>A0A1C7NG22_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">WD repeat domain-containing protein 83</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">WDR83</name>
        <name evidence="7" type="ORF">A0J61_04272</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the WD repeat MORG1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000205">
        <property type="protein sequence ID" value="OBZ87679.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NG22"/>
    <dbReference type="FunCoup" id="A0A1C7NG22">
        <property type="interactions" value="141"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NG22"/>
    <dbReference type="InParanoid" id="A0A1C7NG22"/>
    <dbReference type="OrthoDB" id="1068471at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071013">
        <property type="term" value="C:catalytic step 2 spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045292">
        <property type="term" value="P:mRNA cis splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051980">
        <property type="entry name" value="WD_repeat_MORG1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22842:SF3">
        <property type="entry name" value="WD REPEAT DOMAIN-CONTAINING PROTEIN 83"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22842">
        <property type="entry name" value="WD40 REPEAT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 6" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="35"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="77"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="119"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="287"/>
            <end position="319"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OBZ87679.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="319" mass="35519" checksum="A23555D1DB10CFBB" modified="2016-11-30" version="1">MKFDWSQLLFPSVLFCLFYFLNFMTAYPTRIETTLKGHKGPINDVCYNHSGQYCLSGGRDRSIRLWNPSTGLLLHTYNGHGRDVLGIACSSDNAKIASGGADRTVLLWDVGTGEIMRRYTAHWERVNSVAFNDDATVLISGSFDATIRLWDLRSSNFQPIQVMEDCKDSVMSVDVRGPEIVAGCADGKLRTYDIRMGDLKEDYIGPAITSARLSKDKNCILVSSLDSTMRFMDKSNGRLLNEFKGHTHQSYKLDSVLSNTDAYAITGSEDGRIYIYDVLEANIVATLKAHEGVTTTLDYHPDNINMISAGSDGLIHIWA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NHD0</accession>
    <name>A0A1C7NHD0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">E3 UFM1-protein ligase 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_03520</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000153">
        <property type="protein sequence ID" value="OBZ88418.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NHD0"/>
    <dbReference type="STRING" id="101091.A0A1C7NHD0"/>
    <dbReference type="InParanoid" id="A0A1C7NHD0"/>
    <dbReference type="OrthoDB" id="10258297at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061666">
        <property type="term" value="F:UFM1 ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990592">
        <property type="term" value="P:protein K69-linked ufmylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032434">
        <property type="term" value="P:regulation of proteasomal ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034976">
        <property type="term" value="P:response to endoplasmic reticulum stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018611">
        <property type="entry name" value="Ufl1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056761">
        <property type="entry name" value="Ufl1-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056579">
        <property type="entry name" value="Ufl1_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31057">
        <property type="entry name" value="E3 UFM1-PROTEIN LIGASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31057:SF0">
        <property type="entry name" value="E3 UFM1-PROTEIN LIGASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09743">
        <property type="entry name" value="E3_UFM1_ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25041">
        <property type="entry name" value="UFL1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0436">Ligase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="E3 UFM1-protein ligase 1-like N-terminal" evidence="1">
        <location>
            <begin position="6"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="domain" description="E3 UFM1-protein ligase-like C-terminal" evidence="2">
        <location>
            <begin position="586"/>
            <end position="647"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF09743"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF25041"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ88418.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="665" mass="77313" checksum="025B8CD97BD30AA1" modified="2016-11-30" version="1">MTPTLDLVSQLIEQGIQKGLVQQVHRTLDGKHYLAHHYIEDTIQTIVKRDRRTTLSRLAKELGLEQAIVEDKVPFLHQNWTCVDDLILTDDYLEMIQKELARSLESNGCMSIASQVQGLKLPYAFIKSMVSRQFDTEDYVHYPTLPDLITTKEYTENSKSNIQSLLLSLEEPYPVFKLQKSMTMPEDLFYFKVYLEQLVQENTTLGLLRGKRSRAIFEPKQYRQRQLTLIKSIFDSNECITMDTVESLYAFSNPLDLIHDAYGKDSFLSLHSCLIKHTVKQRAREAIESMVDYCDVNDILPEGLTFKDVNKVVDLVMDDMNTNNKRQVDGGYVITTDYMDHLVNESSLYLRSLLVRHQSKLSDSEIIKAFENLGCPHHIAEKILPFKRTEMIKHYAELLKTPYLETGMTASDDPWIQEHKSLTRKKLCNLRQSIYFNYQAAQLFGDAKRSLEKYILKTQCIEFLFQLVIYLILDQSYNKAEVSQSSSLCISLEDIERQRVVDAKERKWVVTYFIRENDHKYDKTSVVEMEALMKKKDLELFVTTILVQDKHHLFNGENLESERTRQQASTLIYSQLHSQLKRLPLSTQTAPELLHLVSLLLFQKTYRIPLYVSGKFVPAILEQVKPLISQEDQHLLTVTHLSIVNNKREEHMDDFRALNQLGMTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NHH7</accession>
    <name>A0A1C7NHH7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Transcription factor GATA-4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">GATA4</name>
        <name evidence="11" type="ORF">A0J61_03361</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000143">
        <property type="protein sequence ID" value="OBZ88582.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NHH7"/>
    <dbReference type="STRING" id="101091.A0A1C7NHH7"/>
    <dbReference type="InParanoid" id="A0A1C7NHH7"/>
    <dbReference type="OrthoDB" id="515401at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000122">
        <property type="term" value="P:negative regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00202">
        <property type="entry name" value="ZnF_GATA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.50.10:FF:000007">
        <property type="entry name" value="Nitrogen regulatory AreA, N-terminal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.50.10">
        <property type="entry name" value="Erythroid Transcription Factor GATA-1, subunit A"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013860">
        <property type="entry name" value="AreA_GATA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039355">
        <property type="entry name" value="Transcription_factor_GATA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000679">
        <property type="entry name" value="Znf_GATA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013088">
        <property type="entry name" value="Znf_NHR/GATA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10071:SF281">
        <property type="entry name" value="BOX A-BINDING FACTOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10071">
        <property type="entry name" value="TRANSCRIPTION FACTOR GATA FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00320">
        <property type="entry name" value="GATA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08550">
        <property type="entry name" value="GATA_AreA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00619">
        <property type="entry name" value="GATAZNFINGER"/>
    </dbReference>
    <dbReference type="SMART" id="SM00401">
        <property type="entry name" value="ZnF_GATA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57716">
        <property type="entry name" value="Glucocorticoid receptor-like (DNA-binding domain)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00344">
        <property type="entry name" value="GATA_ZN_FINGER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50114">
        <property type="entry name" value="GATA_ZN_FINGER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0804">Transcription</keyword>
    <keyword evidence="5" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 8" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="GATA-type" evidence="10">
        <location>
            <begin position="352"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="domain" description="GATA-type" evidence="10">
        <location>
            <begin position="404"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="83"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="264"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="301"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="455"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="89"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="264"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="310"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="461"/>
            <end position="471"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00094"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50114"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="OBZ88582.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="556" mass="61153" checksum="F0C284F56902637B" modified="2016-11-30" version="1">MAPIVLKIKGDKTFSSFSALASEEDLSQAWRVCSKVRDSLEQGSRLENLSWRLWHRHHTVTEGPSFKTLSATTARKLSNQCTLSPTQPKVEHSPVHPLERTEPDIPMAEPLRFPDSFYNSQQNTHFGLAEFNGSGNVVELDDIFHAFSNSFAIPTAPMDMADGWDFGIPSPTNPYYSPSQSNSTTPPSATQVNAPSLQLEETNTSPVLLNFDMMATSNEISTNSSNDAMYVSGSTMPPPPTATLRNKILGSIHQQQQQFNSSGQLYNTTNQTPPMSASSSVSTAGSNTSVQLNLLVDDTNHTLGNHLLNPPSSHFNQPTPVSAPNSPPSFDSVKSNNRTASSHLDHQDRPICTNCGATSTPLWRRSAEDELLCNACGLYQKLHNAPRPKTLKPHNARKEARDDESSQLVCSNCSTTTTPLWRRDDEGAPLCNACGLYLKLHHERRPLSMKTDIIKKRQRYESNVNSTTPGRKNTKKSKPEPSPPASRMEEMLSNPTTSFPQSLYVNNDCLEFPTITHSDNISDDVSAAVAAAFTGYPSSHFTNPTSTETMMSGNYY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NHP0</accession>
    <name>A0A1C7NHP0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="12">ABC transporter G family member 21</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">abcG21_0</name>
        <name evidence="12" type="ORF">A0J61_03321</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ABC transporter superfamily. ABCG family. PDR (TC 3.A.1.205) subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000140">
        <property type="protein sequence ID" value="OBZ88633.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="FunCoup" id="A0A1C7NHP0">
        <property type="interactions" value="139"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NHP0"/>
    <dbReference type="InParanoid" id="A0A1C7NHP0"/>
    <dbReference type="OrthoDB" id="245989at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03233">
        <property type="entry name" value="ABCG_PDR_domain1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03232">
        <property type="entry name" value="ABCG_PDR_domain2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000054">
        <property type="entry name" value="ABC multidrug transporter atrF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013525">
        <property type="entry name" value="ABC2_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029481">
        <property type="entry name" value="ABC_trans_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043926">
        <property type="entry name" value="ABCG_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034001">
        <property type="entry name" value="ABCG_PDR_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034003">
        <property type="entry name" value="ABCG_PDR_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010929">
        <property type="entry name" value="PDR_CDR_ABC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19241">
        <property type="entry name" value="ATP-BINDING CASSETTE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01061">
        <property type="entry name" value="ABC2_membrane"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19055">
        <property type="entry name" value="ABC2_membrane_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14510">
        <property type="entry name" value="ABC_trans_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06422">
        <property type="entry name" value="PDR_CDR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="522"/>
            <end position="542"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="563"/>
            <end position="593"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="599"/>
            <end position="620"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="627"/>
            <end position="647"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="736"/>
            <end position="755"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1145"/>
            <end position="1162"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1174"/>
            <end position="1194"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1215"/>
            <end position="1240"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1252"/>
            <end position="1276"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1288"/>
            <end position="1310"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1408"/>
            <end position="1428"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="11">
        <location>
            <begin position="135"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="11">
        <location>
            <begin position="807"/>
            <end position="1050"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="OBZ88633.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="1433" mass="162276" checksum="142F8C35556045BA" modified="2016-11-30" version="1">MSLPNQPHRNSVDSDGNTIAERDEKYVPLAQVHSRGGYGEADGNAVDIENAIEEYRSLERELTRQSLAASRNNQDTEKGQGFDLTEFLSDQHSQLTSAGLKPKNMGVIWKNLSAYGLSAEARSIRTNVSAFTDALQFWNWGRKKGTDVTIIHEVDGFVKSGEMLLVLGRPGAGCSTLLRILANIRSGYTNITGEVTYGGIDALEFGKYFKGEVGYNEEEDVHYPTLTTEQTLRFALKNKTPSTRLPGETRKDFVNKILYMLGNMLGLTKQMHTKVGNAFVRGLSGGERKRLSIAEQMTTHSSINCWDCSTRGLDASSALDYVRSLRIMTDIMHKTTISTLYQASDNIFELFDKVMVLDESRCIYFGPTSEAKQYFVDMGFHCPSRKSTPDFLTGLCNLNEREIQEGYESKVPLNAAQFEKVYKESEMYKEMMAQRQAYEEEICKDKPYETFKQAFQQAHSSSPIYSYYQQVKSLTVREYQLIQGDIMSLIIRFADVIVKGLITASVFYMMPLDGTGAFSRSGAILFIVLIIAFIAQGELPTFMEGRGILQKHKRFAMYHPSALYIAQVIIDFPLAILQSIVFTLCVYFIMGLALDAGKFFFMFINLVFLTLCVNGFFRFWGAISPNFYIASQVSGILFIALVMYTGYQIPYPRMHPWLMWIYWINPLAYNFKALLSSEMTGAAFSCEGPNAVPYGPSYTEQAYRACVLPGGNPGDEYVLGDNYLKFVYDYDTWQKWIDFVAVALFFVLFTALTALSMEYVEYNQGGSITKVYKKGFSPIEETEESQLKQTTKHEEQDMEAVSDGTTFSWHNINYTVPVKGGTRQLLDNVSGIVKPGHLTALMGSSGAGKTTLLDVLARRKTIGKIEGQIYMNGEHLASDFERLTGYCEQMDVHNPNATVREALQFSAYLRQPADIPKEEKDAYVEQIIDLLEMKKIGDALVGDLSTGTGISVEERKRLTIAIELVGKPKLLFLDEPTSGLDAQSSFNIIRFIRKLADAGWPVLCTIHQPSATLFEHFDHLILLVRGGKTAYFGEIGKDSRTMIDYFESNNGPICSPKANPAEYILECVGAGTASNNTQDWAEIWKNSPQAKALEDELNEIDRSMDHTVKRQVKTYALPFWSQLFLVFKRMNTSWWRAPSYNVGRMLNLTFIALIAGFTFFQIGNTSWDMQNRMFAILVTMFSGNLFIILIQARFMEERLWFRREYASRYYSWGPFALSCVLVEFPYIVTSAALFLVIYYWTVGFTNASDRAGYFFLHFIAYLSHSVSSGYAIAAACESMSLPGIINPVYLTILYNFTGLFTPPSAMPRFWSSWMYWLDPYHYFIEGLVTNALDGVKVECGNDDVIKIKSPPGQTCGQYMSEYFASGGLGYVTNPDSTDYCNYCQYSTGNEYYETRIGWSFSNRWRNFGILWIFTAFNICLFVLFTYLLRKPKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NHR8</accession>
    <name>A0A1C7NHR8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Acyl carrier protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="primary">MTACP2</name>
        <name evidence="16" type="ORF">A0J61_03364</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="14">Carrier of the growing fatty acid chain in fatty acid biosynthesis.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2">Lipid metabolism; fatty acid biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the acyl carrier protein (ACP) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000143">
        <property type="protein sequence ID" value="OBZ88585.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NHR8"/>
    <dbReference type="FunCoup" id="A0A1C7NHR8">
        <property type="interactions" value="411"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NHR8"/>
    <dbReference type="InParanoid" id="A0A1C7NHR8"/>
    <dbReference type="OrthoDB" id="448946at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0099128">
        <property type="term" value="C:mitochondrial [2Fe-2S] assembly complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000035">
        <property type="term" value="F:acyl binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000036">
        <property type="term" value="F:acyl carrier activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016226">
        <property type="term" value="P:iron-sulfur cluster assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009107">
        <property type="term" value="P:lipoate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1200.10:FF:000003">
        <property type="entry name" value="Acyl carrier protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.10">
        <property type="entry name" value="ACP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01217">
        <property type="entry name" value="Acyl_carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003231">
        <property type="entry name" value="ACP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036736">
        <property type="entry name" value="ACP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009081">
        <property type="entry name" value="PP-bd_ACP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006162">
        <property type="entry name" value="Ppantetheine_attach_site"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00517">
        <property type="entry name" value="acyl_carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF002148">
        <property type="entry name" value="PRK00982.1-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20863">
        <property type="entry name" value="ACYL CARRIER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20863:SF28">
        <property type="entry name" value="ACYL CARRIER PROTEIN, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00550">
        <property type="entry name" value="PP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47336">
        <property type="entry name" value="ACP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50075">
        <property type="entry name" value="CARRIER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00012">
        <property type="entry name" value="PHOSPHOPANTETHEINE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0249">Electron transport</keyword>
    <keyword evidence="13 14" id="KW-0275">Fatty acid biosynthesis</keyword>
    <keyword evidence="8" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="6 14" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="11" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="12" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5 14" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="7" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Carrier" evidence="15">
        <location>
            <begin position="39"/>
            <end position="114"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010930"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU000722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="OBZ88585.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="117" mass="12843" checksum="123021C8DFD7506A" modified="2016-11-30" version="1">MFLRPNAILSAASRAAATQRTRVVAPAVFSRMYASLPKEDVQSRVLDVVKSFEKVDAAKVTPDSSFIKDLGLDSLDTVEVVMAIEEEFSVEIPDKEADAIHSIKQAIDYIASREDAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NHS3</accession>
    <name>A0A1C7NHS3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Chromatin structure-remodeling complex subunit RSC7</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">NPL6_0</name>
        <name evidence="2" type="ORF">A0J61_03268</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000137">
        <property type="protein sequence ID" value="OBZ88682.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="FunCoup" id="A0A1C7NHS3">
        <property type="interactions" value="179"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NHS3"/>
    <dbReference type="InParanoid" id="A0A1C7NHS3"/>
    <dbReference type="OrthoDB" id="5598844at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013933">
        <property type="entry name" value="CRC_Rsc7/Swp82"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08624">
        <property type="entry name" value="CRC_subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="120"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="16"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="50"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="68"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="146"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="164"/>
            <end position="180"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ88682.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="450" mass="50944" checksum="5595EF579202B3C4" modified="2016-11-30" version="1">MAKRKRSRSRSGGLDEKDDLNYVDEDSELSSGDDGLDASDLDNPTPDGHIRKRGRPKTHYGREERTRSPAQTPTSNQSYNQAPATPSGYISDIDESGETKVDKXVLIILFDEKDDLNYVDEDSELSSGDDGLDASDLDNPTPDGHIRKRGRPKTHYGREERTRSPAQTPTSNQSYNQAPATPSGYISDIDESGETKVDKYGRLLGGREYRVPTFTLPTRDNTLFMFSKDPAALLGFRDSFVFLKKNVKLQKVHIDNTEKGHLVDLNLLRSTFRTREISVVTARSVFKQFGHRVVRKGRKGRDDYYYTDEVDEGEDEPSDEEPVIKEILDKPTSSAAFLPVNVEVGRNNLIHKLTPQDTMSTELNWLHNAAVSARQFNTSLFSYRRANPTNYDLMTNVYQIPENRQSLRDTSSFMTDNKQDDTMLMNNSNNTLDNNIAMMNQPKMEMDVGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NHW8</accession>
    <name>A0A1C7NHW8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Cryptochrome DASH</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">cry-dash</name>
        <name evidence="10" type="ORF">A0J61_05009</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">May have a photoreceptor function.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>(6R)-5,10-methylene-5,6,7,8-tetrahydrofolate</name>
            <dbReference type="ChEBI" id="CHEBI:15636"/>
        </cofactor>
        <text evidence="7">Binds 1 5,10-methenyltetrahydrofolate (MTHF) per subunit.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5 7">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
        <text evidence="5 7">Binds 1 FAD per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the DNA photolyase class-1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000259">
        <property type="protein sequence ID" value="OBZ86934.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NHW8"/>
    <dbReference type="STRING" id="101091.A0A1C7NHW8"/>
    <dbReference type="InParanoid" id="A0A1C7NHW8"/>
    <dbReference type="OrthoDB" id="435881at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003684">
        <property type="term" value="F:damaged DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003904">
        <property type="term" value="F:deoxyribodipyrimidine photo-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000719">
        <property type="term" value="P:photoreactive repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.579.10">
        <property type="entry name" value="DNA Cyclobutane Dipyrimidine Photolyase, subunit A, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014133">
        <property type="entry name" value="Cry_DASH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036134">
        <property type="entry name" value="Crypto/Photolyase_FAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036155">
        <property type="entry name" value="Crypto/Photolyase_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005101">
        <property type="entry name" value="Cryptochr/Photolyase_FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002081">
        <property type="entry name" value="Cryptochrome/DNA_photolyase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006050">
        <property type="entry name" value="DNA_photolyase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02765">
        <property type="entry name" value="crypto_DASH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11455">
        <property type="entry name" value="CRYPTOCHROME"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11455:SF22">
        <property type="entry name" value="CRYPTOCHROME DASH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00875">
        <property type="entry name" value="DNA_photolyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03441">
        <property type="entry name" value="FAD_binding_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00147">
        <property type="entry name" value="DNAPHOTLYASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48173">
        <property type="entry name" value="Cryptochrome/photolyase FAD-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52425">
        <property type="entry name" value="Cryptochrome/photolyase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51645">
        <property type="entry name" value="PHR_CRY_ALPHA_BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0157">Chromophore</keyword>
    <keyword evidence="3 5 7" id="KW-0274">FAD</keyword>
    <keyword evidence="2 5 7" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Photolyase/cryptochrome alpha/beta" evidence="9">
        <location>
            <begin position="5"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="359"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="359"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="261"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="274"/>
            <end position="278"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="325"/>
            <end position="332"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="447"/>
            <end position="449"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="site" description="Electron transfer via tryptophanyl radical" evidence="6">
        <location>
            <position position="381"/>
        </location>
    </feature>
    <feature type="site" description="Electron transfer via tryptophanyl radical" evidence="6">
        <location>
            <position position="434"/>
        </location>
    </feature>
    <feature type="site" description="Electron transfer via tryptophanyl radical" evidence="6">
        <location>
            <position position="457"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR602081-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR602081-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU367151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51645"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OBZ86934.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="567" mass="67286" checksum="3B109CFC973C1202" modified="2016-11-30" version="1">MMTNSINICFFRNVLRVHDNMSLHAILKTNSQLLPVVCIDPRMIDISRINKKINQNFEPPKTWYFKFDRVANFRTRFLYECIKSLKKELKNRDSDLLILYGKPEEVLPKLKKHLTDNNLKVDKIHTHKEYAFEELRNEKDLSKAMDDDVVYHHDTMLVNPDDLDFVGERTYKVYTHFRKRIEAMENPVRAPLEIPKKLPAFPEVAWTFEHAKQGEELLQELYEHVPVKKDERTAFPWEGGEHSALERLNNYCFKSDGVANYKHTRNGLVGTEYSTKFSAFLANGCLSPRTIWHEMDLFEQQDGKKRKRSVKPHSDDDGVYWVKFELLWRDFFRLLTIGYGKRIFMLHGFRNLEKPEIAKEDRKKKVDKPPHPKNSYQDKVWRSDDDQFNKWADGETGIPFIDASMREMKYTGFLNNRGRQNVASFFAKDLEIDWRLGAEYFEYMLRDHDVYSNYGNWQYVAGVGCDPREGFRHFNILKQGFDYDPDAEYIKLWCPELKDLPTHYAHCPWLMSEEEQEEHKCKIGSDYPKPMAIFENWKRYYPAEAKKGSLHKFMKGGKEKTKKTKTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NI20</accession>
    <name>A0A1C7NI20_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Proteasome subunit alpha type</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">pup2</name>
        <name evidence="8" type="ORF">A0J61_03303</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="4">The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits. The 20S proteasome core is composed of 28 subunits that are arranged in four stacked rings, resulting in a barrel-shaped structure. The two end rings are each formed by seven alpha subunits, and the two central rings are each formed by seven beta subunits. The catalytic chamber with the active sites is on the inside of the barrel.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="6">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5 6">Belongs to the peptidase T1A family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000139">
        <property type="protein sequence ID" value="OBZ88658.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NI20"/>
    <dbReference type="FunCoup" id="A0A1C7NI20">
        <property type="interactions" value="666"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NI20"/>
    <dbReference type="InParanoid" id="A0A1C7NI20"/>
    <dbReference type="OrthoDB" id="431557at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019773">
        <property type="term" value="C:proteasome core complex, alpha-subunit complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034515">
        <property type="term" value="C:proteasome storage granule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010499">
        <property type="term" value="P:proteasomal ubiquitin-independent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043161">
        <property type="term" value="P:proteasome-mediated ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd03753">
        <property type="entry name" value="proteasome_alpha_type_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.20.10:FF:000015">
        <property type="entry name" value="Proteasome subunit alpha type-5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.10">
        <property type="entry name" value="Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050115">
        <property type="entry name" value="Proteasome_alpha"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023332">
        <property type="entry name" value="Proteasome_alpha-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033812">
        <property type="entry name" value="Proteasome_alpha_type_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000426">
        <property type="entry name" value="Proteasome_asu_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001353">
        <property type="entry name" value="Proteasome_sua/b"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003075">
        <property type="entry name" value="PRK03996.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11599">
        <property type="entry name" value="PROTEASOME SUBUNIT ALPHA/BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00227">
        <property type="entry name" value="Proteasome"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10584">
        <property type="entry name" value="Proteasome_A_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00948">
        <property type="entry name" value="Proteasome_A_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="N-terminal nucleophile aminohydrolases (Ntn hydrolases)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00388">
        <property type="entry name" value="PROTEASOME_ALPHA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51475">
        <property type="entry name" value="PROTEASOME_ALPHA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="2 5 6" id="KW-0647">Proteasome</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Proteasome alpha-type subunits" evidence="7">
        <location>
            <begin position="8"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00026071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00808"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS00388"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OBZ88658.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="242" mass="26633" checksum="D54977FEE54EA3AD" modified="2016-11-30" version="1">MFLTRSEYDRGVNTFSPEGRLFQVEYAIEAIKLGTTAIGVQTSEGVVLAVEKRVSSSLLEPSSIEKVMEIDTHLGCAVSGMTADARTMIEHARVAAQNHRFTYDEHLKVESVTQSVCDLALRFGEGAEGEESIMSRPFGVALLIAGVDENGPQLFHADPSGTFMKYQAKAIGSGSEGAQTELQKEYHKSMTLKEAETLALTVLKSVMEEKLNKTNVQIASVTPEHNFRIYSEEELQSIIERL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NJT1</accession>
    <name>A0A1C7NJT1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Late endosomal/lysosomal adaptor and MAPK and MTOR activator 5</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">A0J61_04411</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Lysosome</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the LAMTOR5 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000215">
        <property type="protein sequence ID" value="OBZ87544.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NJT1"/>
    <dbReference type="InParanoid" id="A0A1C7NJT1"/>
    <dbReference type="OrthoDB" id="76862at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071986">
        <property type="term" value="C:Ragulator complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005085">
        <property type="term" value="F:guanyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071230">
        <property type="term" value="P:cellular response to amino acid stimulus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043066">
        <property type="term" value="P:negative regulation of apoptotic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1904263">
        <property type="term" value="P:positive regulation of TORC1 signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.30">
        <property type="entry name" value="Dynein light chain 2a, cytoplasmic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024135">
        <property type="entry name" value="LAMTOR5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13342">
        <property type="entry name" value="RAGULATOR COMPLEX PROTEIN LAMTOR5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13342:SF2">
        <property type="entry name" value="RAGULATOR COMPLEX PROTEIN LAMTOR5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16672">
        <property type="entry name" value="LAMTOR5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103196">
        <property type="entry name" value="Roadblock/LC7 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0458">Lysosome</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007795"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023228"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00032692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OBZ87544.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="91" mass="10075" checksum="FCE87A0C7CAA4CAE" modified="2016-11-30" version="1">MEEELIATLDNLSNKEGVKGVLVADEKGLCLGVRGIARSESAAFITSIANNARRLEKTHEDKLECPTIHLQYENNQVVVRNEGTFTLAIFM</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NK11</accession>
    <name>A0A1C7NK11_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Zinc transporter ZIP9</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">SLC39A9</name>
        <name evidence="8" type="ORF">A0J61_02466</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Golgi apparatus membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000093">
        <property type="protein sequence ID" value="OBZ89492.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NK11"/>
    <dbReference type="STRING" id="101091.A0A1C7NK11"/>
    <dbReference type="InParanoid" id="A0A1C7NK11"/>
    <dbReference type="OrthoDB" id="19859at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046873">
        <property type="term" value="F:metal ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006829">
        <property type="term" value="P:zinc ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003689">
        <property type="entry name" value="ZIP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045891">
        <property type="entry name" value="ZIP9"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16133">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 39 ZINC TRANSPORTER , MEMBER 9-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16133:SF0">
        <property type="entry name" value="ZINC_IRON REGULATED TRANSPORTER-RELATED PROTEIN 102B, ISOFORM E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02535">
        <property type="entry name" value="Zip"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="27"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="67"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="172"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="207"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="239"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="269"/>
            <end position="286"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004394"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OBZ89492.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="292" mass="31176" checksum="53A638F52D76336C" modified="2016-11-30" version="1">MLVASFVAGCIPLATKLSETKLNTLTFISVGLLISTSLVVIIPEGVETLYTNKAPETIDAPGEAKHLHLADHTAVGLSLLVGFAVMFIIDHISTMHVHPTNTASEPANFKSRNSLELDAMLAPTSNASSSSPDTTTAPHTHDLTTPTIGLIVHAAADGIALGASASHPQLSIVVFFAIMLHKAPSAFALTTVLLSEGLSRTRVRQHLLMFSLSAPTGAISTYALLHFFSESVLTVNLEYWTGVLLLFSGGTFLYVAMHAIHELPSNKGDYWQMGSILLGMLIPFVLNMNHSH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NK59</accession>
    <name>A0A1C7NK59_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Trehalose-phosphatase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">tpp1_2</name>
        <name evidence="4" type="ORF">A0J61_02779</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">In the C-terminal section; belongs to the trehalose phosphatase family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">In the N-terminal section; belongs to the glycosyltransferase 20 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000109">
        <property type="protein sequence ID" value="OBZ89179.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NK59"/>
    <dbReference type="FunCoup" id="A0A1C7NK59">
        <property type="interactions" value="53"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NK59"/>
    <dbReference type="InParanoid" id="A0A1C7NK59"/>
    <dbReference type="OrthoDB" id="755951at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005946">
        <property type="term" value="C:alpha,alpha-trehalose-phosphate synthase complex (UDP-forming)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003825">
        <property type="term" value="F:alpha,alpha-trehalose-phosphate synthase (UDP-forming) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004805">
        <property type="term" value="F:trehalose-phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005992">
        <property type="term" value="P:trehalose biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03788">
        <property type="entry name" value="GT20_TPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01627">
        <property type="entry name" value="HAD_TPP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1000:FF:000052">
        <property type="entry name" value="Alpha,alpha-trehalose-phosphate synthase [UDP-forming] 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.2000:FF:000036">
        <property type="entry name" value="Alpha,alpha-trehalose-phosphate synthase subunit Tps2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.1020:FF:000002">
        <property type="entry name" value="Trehalose-6-phosphate synthase 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2000">
        <property type="entry name" value="Glycogen Phosphorylase B"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1020">
        <property type="entry name" value="Trehalose-6-phosphate phosphatase related protein, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001830">
        <property type="entry name" value="Glyco_trans_20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006379">
        <property type="entry name" value="HAD-SF_hydro_IIB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003337">
        <property type="entry name" value="Trehalose_PPase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01484">
        <property type="entry name" value="HAD-SF-IIB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF011071">
        <property type="entry name" value="PRK14501.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00685">
        <property type="entry name" value="T6PP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10788">
        <property type="entry name" value="TREHALOSE-6-PHOSPHATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10788:SF123">
        <property type="entry name" value="TREHALOSE-PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00982">
        <property type="entry name" value="Glyco_transf_20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02358">
        <property type="entry name" value="Trehalose_PPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53756">
        <property type="entry name" value="UDP-Glycosyltransferase/glycogen phosphorylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="41"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="45"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006330"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OBZ89179.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="851" mass="96410" checksum="E85E2B2CF7842F92" modified="2016-11-30" version="1">MSSLTAEKVADYLPLAGKMPKISGRIINVTHQIPYHISRSGPTMVEQKQPEQQQQQQQQEVPVGRRESIFDNVAAAPISKLARHHVRTRTLRAKFQAAEWVIVQNRGHGALNSGLQSLNDEYQTLHIGWTGPIKDEATKKSIPAEELSEQDKDKIQSLLMQNGNIMPVFLDSKSRGHYEGYCKEVLWPLFHYLVWTNDTDGRSEKKYWEDYVAVNRVFADTIASQYKPGDVIFINDYHLLLVPEMLREKIHDAPIGLFLHATFPSSEIFRCLTTRKEILHGFLGANLVGFQTYSYARHFIGACTRVLGCESTQTGVNVNGHIVSVGTFPIGIDADRVDQFRHEPNVAPKMKAIRDMYAGKKVIIGRDKLDSTKGVLQKLHAFEKFLKDYPEFRQEVVLVQVTTPTYGDNSKLETKVSELVSHINGLYGNLQHQPVHHYYQDIDRDEYYALLSVADVGLITSLRDGMNTTSLEYIICQQETHGPLILSEFTGTAGSLGAAMIVNPFDYAGVAKAIYDALVMSPEDKATRNKQLFQYVREHSAAYWARSFIKQLVESTKNFSLQSQSTPALKSDQFIDQYKKAKKRVMFFDYDGTLTPIVSVPTDAKPSQEMLQYLQKLCDDPRNEIWIISGRDQACLEDWLGGITNLGLSAEHGCFLKPAGSNQWTDVLEGIDMAWKKDVTEIFNYYTERTEGSFVEHKKSSITWHYRMADEEYGLFQAKECQNHLENTIVSKMPVEILVGKKNLEVRPMMVNKGEVVKRILALSPEPDFIVCAGDDKTDEDMFRTLSATYFAKYQNEINEGKSSANWENTKSQLYSITVGPVMKKSMANWQVEAPANVIELLGKMVEADKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NKJ9</accession>
    <name>A0A1C7NKJ9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Elongation of fatty acids protein</fullName>
            <ecNumber evidence="12">2.3.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">A0J61_04147</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>a very-long-chain acyl-CoA + malonyl-CoA + H(+) = a very-long-chain 3-oxoacyl-CoA + CO2 + CoA</text>
            <dbReference type="Rhea" id="RHEA:32727"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57384"/>
            <dbReference type="ChEBI" id="CHEBI:90725"/>
            <dbReference type="ChEBI" id="CHEBI:90736"/>
            <dbReference type="EC" id="2.3.1.199"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>an acyl-CoA + malonyl-CoA + H(+) = a 3-oxoacyl-CoA + CO2 + CoA</text>
            <dbReference type="Rhea" id="RHEA:50252"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57384"/>
            <dbReference type="ChEBI" id="CHEBI:58342"/>
            <dbReference type="ChEBI" id="CHEBI:90726"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="12">
            <dbReference type="Rhea" id="RHEA:50253"/>
        </physiologicalReaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 12">Belongs to the ELO family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.-" evidence="12"/>
    <dbReference type="EMBL" id="LUGH01000196">
        <property type="protein sequence ID" value="OBZ87804.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NKJ9"/>
    <dbReference type="STRING" id="101091.A0A1C7NKJ9"/>
    <dbReference type="InParanoid" id="A0A1C7NKJ9"/>
    <dbReference type="OrthoDB" id="434092at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009922">
        <property type="term" value="F:fatty acid elongase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034625">
        <property type="term" value="P:fatty acid elongation, monounsaturated fatty acid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034626">
        <property type="term" value="P:fatty acid elongation, polyunsaturated fatty acid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019367">
        <property type="term" value="P:fatty acid elongation, saturated fatty acid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030148">
        <property type="term" value="P:sphingolipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042761">
        <property type="term" value="P:very long-chain fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030457">
        <property type="entry name" value="ELO_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002076">
        <property type="entry name" value="ELO_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11157:SF134">
        <property type="entry name" value="ELONGATION OF FATTY ACIDS PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11157">
        <property type="entry name" value="FATTY ACID ACYL TRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01151">
        <property type="entry name" value="ELO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01188">
        <property type="entry name" value="ELO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 12" id="KW-0275">Fatty acid biosynthesis</keyword>
    <keyword evidence="6 12" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="3 12" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="8 12" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="9 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 12" id="KW-0808">Transferase</keyword>
    <keyword evidence="5 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 12" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="53"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="83"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="181"/>
            <end position="201"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007263"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00047375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU361115"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="OBZ87804.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="211" mass="24593" checksum="43F397955FEB376E" modified="2016-11-30" version="1">MEALKHLHFTPETPFGLPLYPIFEKAFEAVVGQPASEFRYVPGVTPLSTVNEVTITCITYFITIFGGRYLMTNMPAFKLKVPFMIHNILLTLVSGILLVLMVEQIFPILYRQGFLAAICAQTTWTQPLELLYYLNYLVKYWELIDTLFLVLKKKNLEFLHYYHHSLTMVLCFTQLNGRTSVSWVPIILNLTVHVLMYYYYFRTAADHSIHH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NLM0</accession>
    <name>A0A1C7NLM0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Very-long-chain 3-oxoacyl-CoA reductase</fullName>
            <ecNumber evidence="12">1.1.1.330</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12">3-ketoacyl-CoA reductase</fullName>
            <shortName evidence="12">3-ketoreductase</shortName>
            <shortName evidence="12">KAR</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="12">Microsomal beta-keto-reductase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">A0J61_02095</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Component of the microsomal membrane bound fatty acid elongation system, which produces the 26-carbon very long-chain fatty acids (VLCFA) from palmitate. Catalyzes the reduction of the 3-ketoacyl-CoA intermediate that is formed in each cycle of fatty acid elongation. VLCFAs serve as precursors for ceramide and sphingolipids.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>a very-long-chain (3R)-3-hydroxyacyl-CoA + NADP(+) = a very-long-chain 3-oxoacyl-CoA + NADPH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:48680"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:85440"/>
            <dbReference type="ChEBI" id="CHEBI:90725"/>
            <dbReference type="EC" id="1.1.1.330"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Lipid metabolism; fatty acid biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="12">Endoplasmic reticulum membrane</location>
            <topology evidence="12">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="12 13">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.330" evidence="12"/>
    <dbReference type="EMBL" id="LUGH01000075">
        <property type="protein sequence ID" value="OBZ89860.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NLM0"/>
    <dbReference type="FunCoup" id="A0A1C7NLM0">
        <property type="interactions" value="548"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NLM0"/>
    <dbReference type="InParanoid" id="A0A1C7NLM0"/>
    <dbReference type="OrthoDB" id="5545019at2759"/>
    <dbReference type="UniPathway" id="UPA00094"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045703">
        <property type="term" value="F:ketoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0141040">
        <property type="term" value="F:very-long-chain 3-oxoacyl-CoA reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030497">
        <property type="term" value="P:fatty acid elongation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030148">
        <property type="term" value="P:sphingolipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042761">
        <property type="term" value="P:very long-chain fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd05356">
        <property type="entry name" value="17beta-HSD1_like_SDR_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000137">
        <property type="entry name" value="Hydroxysteroid (17-beta) dehydrogenase 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03107">
        <property type="entry name" value="3_ketoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027533">
        <property type="entry name" value="3_ketoreductase_fungal"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43086:SF2">
        <property type="entry name" value="HYDROXYSTEROID DEHYDROGENASE-LIKE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43086">
        <property type="entry name" value="VERY-LONG-CHAIN 3-OXOOACYL-COA REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000126">
        <property type="entry name" value="11-beta-HSD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 12" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="11 12" id="KW-0275">Fatty acid biosynthesis</keyword>
    <keyword evidence="5 12" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="2 12" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="9 12" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="10 12 14" id="KW-0472">Membrane</keyword>
    <keyword evidence="6 12" id="KW-0521">NADP</keyword>
    <keyword evidence="8 12" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 12 14" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 12 14" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="6"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="181"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="281"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="12">
        <location>
            <position position="200"/>
        </location>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="187"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03107"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU000363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="OBZ89860.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="324" mass="35510" checksum="EE43336D1AD09BC3" modified="2016-11-30" version="1">MVECNSVTLFAAIGAAFLGYKALALFKILFETFVASGIPLQKFGAGKGSWAVVTGATDGIGKEFALQLAKKKFNVFLISRTASKLDALANDISGQYGVETKTFAMDFTKGDVEDFKKVGQILDTIRVGALINNVGVNHEIPTSFFEEDEALINNIVEVNIKGLMKMTKLVLPQMKENRNGLILNIGSFAGLVATPYLSVYSASKAFLSTWSQALGKEVEKDGIVVEHVSTYFVVSAMSKIRKSSLLIPTAKDYVGNVLKRIGLSCGANVPFTSTPHPMHGVIYWAITNLFTTSFWVNYNDSIQKDIRKRALRKREREAAARKTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NLW6</accession>
    <name>A0A1C7NLW6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Acetyl-CoA hydrolase</fullName>
            <ecNumber evidence="4">3.1.2.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Acetyl-CoA deacylase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="primary">acu-8</name>
        <name evidence="11" type="ORF">A0J61_01808</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>acetyl-CoA + H2O = acetate + CoA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:20289"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30089"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="EC" id="3.1.2.1"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the acetyl-CoA hydrolase/transferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.2.1" evidence="4"/>
    <dbReference type="EMBL" id="LUGH01000062">
        <property type="protein sequence ID" value="OBZ90143.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NLW6"/>
    <dbReference type="FunCoup" id="A0A1C7NLW6">
        <property type="interactions" value="224"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NLW6"/>
    <dbReference type="InParanoid" id="A0A1C7NLW6"/>
    <dbReference type="OrthoDB" id="10250396at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008775">
        <property type="term" value="F:acetate CoA-transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003986">
        <property type="term" value="F:acetyl-CoA hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006083">
        <property type="term" value="P:acetate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.750.70:FF:000002">
        <property type="entry name" value="Acetyl-CoA hydrolase Ach1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.1080.10:FF:000003">
        <property type="entry name" value="Acetyl-coA hydrolase Ach1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.1080.20:FF:000001">
        <property type="entry name" value="Acetyl-CoA hydrolase Ach1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1080.20">
        <property type="entry name" value="Acetyl-CoA hydrolase/transferase C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1080.10">
        <property type="entry name" value="Glutaconate Coenzyme A-transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026888">
        <property type="entry name" value="AcetylCoA_hyd_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038460">
        <property type="entry name" value="AcetylCoA_hyd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046433">
        <property type="entry name" value="ActCoA_hydro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003702">
        <property type="entry name" value="ActCoA_hydro_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037171">
        <property type="entry name" value="NagB/RpiA_transferase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43609">
        <property type="entry name" value="ACETYL-COA HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43609:SF1">
        <property type="entry name" value="ACETYL-COA HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13336">
        <property type="entry name" value="AcetylCoA_hyd_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02550">
        <property type="entry name" value="AcetylCoA_hydro"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100950">
        <property type="entry name" value="NagB/RpiA/CoA transferase-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7 11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Acetyl-CoA hydrolase/transferase N-terminal" evidence="9">
        <location>
            <begin position="14"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="domain" description="Acetyl-CoA hydrolase/transferase C-terminal" evidence="10">
        <location>
            <begin position="333"/>
            <end position="483"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001831"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009632"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011920"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00017958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00029672"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF02550"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF13336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="OBZ90143.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="524" mass="58446" checksum="5561941B39F72E7A" modified="2016-11-30" version="1">MSTVSTALKSRVRRPQLLKKVMKADETLQFFRGGQYLGWSGFTGVGYPKMVPLALADHVEKNNLQGKMKFNLFVGASSGAECEDKWAELDMIDRRYPHQVGKNIKKGINEGRIRFADKHLSMFPQDLVYGYYTKDKPDHKKLDIVVVEATAITEDGWIVPGASVGATPELIQMADKIIIEVNTRLPSFEGLHDISMCDLPPNRKPYLIMNTEDRIGTTAIPVDTDKILAIVESDRPDMTGGNTPADDKSEAIANHLIEFFEHEVKQGRLPENLLPLQSGIGNIANAVIGGLAKSRFQNVTVFTEVLQDTFLEFFDSEKLKFASATSVRFSPEGFDRFYNNWGKYKDRLLLRSQQVSNSPEVIRRLGCIAMNTPVEFDMYGHANSTLVCGSGMLNGLGGSGDFLRNAKISIMHSPSSRPSKKDPNGVSCVVPMVSHVDQTEHDLDIFVTEQGLADLRGLSPRERAQVVIDNCAHPEYKPQLQDYFDMATKKCLAAGRGHEPQMLDKVFKMHTNLLENGTMKLDSW</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NM83</accession>
    <name>A0A1C7NM83_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">DNA replication licensing factor MCM7</fullName>
            <ecNumber evidence="12">3.6.4.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">mcm7</name>
        <name evidence="12" type="synonym">MCM7</name>
        <name evidence="14" type="ORF">A0J61_01962</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Acts as component of the MCM2-7 complex (MCM complex) which is the replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.12"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="10">
            <dbReference type="Rhea" id="RHEA:13066"/>
        </physiologicalReaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 12">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="11">Belongs to the MCM family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.12" evidence="12"/>
    <dbReference type="EMBL" id="LUGH01000069">
        <property type="protein sequence ID" value="OBZ89979.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NM83"/>
    <dbReference type="FunCoup" id="A0A1C7NM83">
        <property type="interactions" value="770"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NM83"/>
    <dbReference type="InParanoid" id="A0A1C7NM83"/>
    <dbReference type="OrthoDB" id="3207464at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031261">
        <property type="term" value="C:DNA replication preinitiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042555">
        <property type="term" value="C:MCM complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005656">
        <property type="term" value="C:nuclear pre-replicative complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043596">
        <property type="term" value="C:nuclear replication fork"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017116">
        <property type="term" value="F:single-stranded DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006270">
        <property type="term" value="P:DNA replication initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006271">
        <property type="term" value="P:DNA strand elongation involved in DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000727">
        <property type="term" value="P:double-strand break repair via break-induced replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006279">
        <property type="term" value="P:premeiotic DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd17758">
        <property type="entry name" value="MCM7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.20.28.10:FF:000004">
        <property type="entry name" value="DNA replication licensing factor MCM7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000288">
        <property type="entry name" value="DNA replication licensing factor MCM7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.28.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1640.10">
        <property type="entry name" value="mini-chromosome maintenance (MCM) complex, chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031327">
        <property type="entry name" value="MCM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008050">
        <property type="entry name" value="MCM7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018525">
        <property type="entry name" value="MCM_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001208">
        <property type="entry name" value="MCM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041562">
        <property type="entry name" value="MCM_lid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027925">
        <property type="entry name" value="MCM_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033762">
        <property type="entry name" value="MCM_OB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11630">
        <property type="entry name" value="DNA REPLICATION LICENSING FACTOR MCM FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11630:SF26">
        <property type="entry name" value="DNA REPLICATION LICENSING FACTOR MCM7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00493">
        <property type="entry name" value="MCM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17855">
        <property type="entry name" value="MCM_lid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14551">
        <property type="entry name" value="MCM_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17207">
        <property type="entry name" value="MCM_OB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24901">
        <property type="entry name" value="WHD_MCM7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01657">
        <property type="entry name" value="MCMFAMILY"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01663">
        <property type="entry name" value="MCMPROTEIN7"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00350">
        <property type="entry name" value="MCM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00847">
        <property type="entry name" value="MCM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50051">
        <property type="entry name" value="MCM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9 12" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="2 12" id="KW-0235">DNA replication</keyword>
    <keyword evidence="7 11" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5 12" id="KW-0347">Helicase</keyword>
    <keyword evidence="4 12" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8 12" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MCM C-terminal AAA(+) ATPase" evidence="13">
        <location>
            <begin position="343"/>
            <end position="549"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00048432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU004070"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU365012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50051"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="OBZ89979.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="737" mass="82904" checksum="C81A24F52A435E3C" modified="2016-11-30" version="1">MAALAPVQIHINYEEEKESLRTFLSEFKQEASSMGEEEAHLKYDVQLQRIVDREQSVLYIELDDLAMFEDSNSRTVANIMKNTKHYIDLASSVIDELLSQKQPANPDLSYKDSVLDVIIRQRSIRDSNRTNETEQTFPPVLTRRYEVFFKPLTGSPAHAVRQINGAELGHLVTVRGIITRVSDVKPFIQVNTYSCDSCGYEIFQEIKQRQFTPLTECVSEECKSNGIKGKLYMQTRASKFLAFQEVKLQELTDQVPVGHIPRTMTLHLYGAACRQLTPGDVANVSGVFLPMPYTGFRALRAGLLTDTYLEVQYVHRLKKQYDEIELTEEDEAKLNALKQDANIYSHLARSIAPEIYGHDDVKKALLLLLVGGVNKTVGDGMKIRGDINICLMGDPGVAKSQLLKFIAKVAPRGVYTTGRGSSGVGLTAAVMRDPVTDEMILEGGALVLADNGICCIDEFDKMDDSDRTAIHEVMEQQTISISKAGINTTLNARASILAAANPLYGRYNTRISPTQNINLPAALLSRFDLLYLILDKPSDDLDRLLAEHVTYVHTHNKPPKMDFDVLEPYMIRHYVAHARTKRPVLTPEVSDYVTSAYVGLRRQYKIDEDRQQQFTYASARTLLGIIRMAQALARVRLSDRVEPMDVDEALRLIDVSKSSLVDDNQKRDGRADRSPTSGIFNIVKELTYQYGSSIALSTIRQRVLSRGYTEAQLTTAIREYTDLDIWQADHARLTVVH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NMS3</accession>
    <name>A0A1C7NMS3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_01556</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000051">
        <property type="protein sequence ID" value="OBZ90385.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NMS3"/>
    <dbReference type="InParanoid" id="A0A1C7NMS3"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="40"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ90385.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="81" mass="9211" checksum="241D0085077D74A4" modified="2016-11-30" version="1">MCAIESFLRLHIAKDLKITDVLVLSFVIINFDLSVIAVSFDLDYLDIASKASSTVDSKRQFLAFYLLCNECKRIKTNVISY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NN13</accession>
    <name>A0A1C7NN13_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_02076</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000074">
        <property type="protein sequence ID" value="OBZ89866.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NN13"/>
    <dbReference type="InParanoid" id="A0A1C7NN13"/>
    <dbReference type="OrthoDB" id="5366606at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="103"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="110"/>
            <end position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ89866.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="145" mass="15710" checksum="6F4BF981AAECCAAA" modified="2016-11-30" version="1">MSFQVMLREGIVGGFAGPTVKQMIQIQGDHTGALIQQHTLKPESKTDFSVQSGGLATDQVSGILDAIKKQLQELPTEQPPGSEDIYGQDISLGFMSDDFQWINGGPEGCSNGTSEVQPTPEQKEKFKELVELVKGLGQQYAIEAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NN84</accession>
    <name>A0A1C7NN84_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_01393</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000044">
        <property type="protein sequence ID" value="OBZ90555.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NN84"/>
    <dbReference type="InParanoid" id="A0A1C7NN84"/>
    <dbReference type="OrthoDB" id="2281940at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008889800" evidence="1">
        <location>
            <begin position="20"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="unsure residue" description="I or L" evidence="2">
        <location>
            <position position="255"/>
        </location>
    </feature>
    <feature type="unsure residue" description="D or N" evidence="2">
        <location>
            <position position="264"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="365"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ90555.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="365" mass="40848" checksum="3E6B991DC03A35D4" modified="2016-11-30" version="1" fragment="single">MIISLTIYILFPLSNIALGEHPFDSCESCAKTGLYFRKRDQAERTKNHLLLLEKDDSINKRNCGIHKVNMCKDVPVFDVAGAFFHGLDEMHLFSNIAKLVYGMLAPTLNKPFNKYRSVDYIDIHRYVIPTLIAPRLDNLATGKALCCLCRGVALAMQRCLSAAEVNEIESNFKKWFGFLNQCVANDSISLTVFRINTHLLSHMGSVIRKLGPMTTYSVRSMERSIGALKKKMKASNRAGVNAGNLIEXDQLIDFLDVHKLIDXDVDSEVKDNSDSGLNPNDLGSSCLCSPFAKTECSFVGSNPEANVEGVVKFRELARAIIHMVSRQQGRATPNWDSIQKKHKIKIAGKIEIDTTSYASEMFRIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NNK1</accession>
    <name>A0A1C7NNK1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="14">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">A0J61_01235</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000037">
        <property type="protein sequence ID" value="OBZ90713.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NNK1"/>
    <dbReference type="InParanoid" id="A0A1C7NNK1"/>
    <dbReference type="OrthoDB" id="48943at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019829">
        <property type="term" value="F:ATPase-coupled monoatomic cation transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140358">
        <property type="term" value="F:P-type transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.150.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, transmembrane domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004014">
        <property type="entry name" value="ATPase_P-typ_cation-transptr_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023299">
        <property type="entry name" value="ATPase_P-typ_cyto_dom_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018303">
        <property type="entry name" value="ATPase_P-typ_P_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023298">
        <property type="entry name" value="ATPase_P-typ_TM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008250">
        <property type="entry name" value="ATPase_P-typ_transduc_dom_A_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059000">
        <property type="entry name" value="ATPase_P-type_domA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006544">
        <property type="entry name" value="P-type_TPase_V"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001757">
        <property type="entry name" value="P_typ_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044492">
        <property type="entry name" value="P_typ_ATPase_HD_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01494">
        <property type="entry name" value="ATPase_P-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01657">
        <property type="entry name" value="P-ATPase-V"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45630">
        <property type="entry name" value="CATION-TRANSPORTING ATPASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45630:SF11">
        <property type="entry name" value="CATION-TRANSPORTING P-TYPE ATPASE N-TERMINAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00690">
        <property type="entry name" value="Cation_ATPase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00122">
        <property type="entry name" value="E1-E2_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00119">
        <property type="entry name" value="CATATPASE"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG00002">
        <property type="entry name" value="C1.7:_P-type_atpase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00003">
        <property type="entry name" value="Haloacid_Dehalogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00027">
        <property type="entry name" value="p-type_atpase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81653">
        <property type="entry name" value="Calcium ATPase, transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81665">
        <property type="entry name" value="Calcium ATPase, transmembrane domain M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81660">
        <property type="entry name" value="Metal cation-transporting ATPase, ATP-binding domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00154">
        <property type="entry name" value="ATPASE_E1_E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0460">Magnesium</keyword>
    <keyword evidence="10 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-1278">Translocase</keyword>
    <keyword evidence="3 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="20"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="104"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="148"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="310"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="333"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="500"/>
            <end position="520"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="526"/>
            <end position="549"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="999"/>
            <end position="1018"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="1024"/>
            <end position="1041"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="1062"/>
            <end position="1086"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="1117"/>
            <end position="1135"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="1147"/>
            <end position="1165"/>
        </location>
    </feature>
    <feature type="domain" description="Cation-transporting P-type ATPase N-terminal" evidence="13">
        <location>
            <begin position="268"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="domain" description="P-type ATPase A" evidence="12">
        <location>
            <begin position="365"/>
            <end position="483"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006000"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF00122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF00690"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="OBZ90713.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="1257" mass="142819" checksum="055589B89F4535E8" modified="2016-11-30" version="1">MWGSCPTADYGTLTFTEPVFIALYVFYGSCVFFLVSWYFYKKTRERYIKSRFHKVDEIRHDDYPISIDEKKAAKAEDDVIASTSSINSDEDNDMVIKAYKRDPFGMLVSVLYFLQTIGMFAYMILLVYDYYQNYLFFRGSAVVQSSTFIAMWYIFFIWLATLTIFKSRLANFFRIQCTYEQGQYIQIEHNEPSIILLEDDDKIMAFVRGLESFGKRLFGLDVVVATATLQKTSAGTKYFIYQCTRYVYHPETQMFKPHQFQLGETNSDLARLTQGLTSQEAMEREQLVGPNFIEVYVPNVFMAVLREFSSFFYIYQFTALWLFYYFAYWQVGIADTAVILVSALVKVFVRLRSEKRIKKMAEFTDTVMILRDGQWFEGSSSDLVPGDVFEVAEGKTAPCDAVVLTGNIVADESSLTGEPLPIRKFPVRSNDPXAYDSLGASKIHTIFSGTTISQAQRTEHDSPVTALVLKTGTATDKGELVKKILFPTRVSFIFDEQIKIVILILLCCGLIMLGLAIWLYTSGTSAWFYAMFAICQLVSPLLPAGLVVGQSVAAGRLRKKQIYCVDLPRILMAGKVQLFCFDKTGTLTKEGLEFFGAKPIADINSIVEQRQNKIIPEFDSHIGNVEDIPRLMQIGIATCHAVTTLNGQFIGNPVDIEMFKASKWTLNDTPEKEEYVDTLTPPMDKPGHVNTPVHVLKRFEFVHARMSMSVAVLDSHTNKIHIFVKGAYEKIKDLCNPDSIPKDYDATTAGLARQGCYVLSLAHREIDLEEIGGMERFRNWSRDEMEQDIDFCGLIIFKNQLKEDTTENILELKRGDTRTIMITGDTALTGVYIARQCKMVQDGARVLLADFDKSLNRLVWTDVDEPEVFADVDVDKVMLNQDHTPYELAMTGKAFEWLCEHDLIRRYLLNTRVFARMTPSGKVKCVQLHMEYGITAMTGDGGNDCGALRAAHVGIAMSDAEASIVSPFSTSNRSVRSCVELIRQGRGALATSITNYKYLVMYGQVMMMLKIFTFYFSITMSQNVWIAIDVLITVLLTWAVSQSHAAKRLEGQRPTARLLGPQTLSSAMGIAAINWLFLIGAFVMLFKQAWFRCHEFDASAVDISKWWLLADNYEAEVLALVTLFQFINNAATFNFGYKFRKSFWRNYALVFLWLLYIAIVSYWTLADPNRFGCLFRFNCGTKQVLNQLGYTPPPTYIEPYNTPLGHNIMPSDFRWKLWGLCVGNMIAALAYEKLVVLGPVHSFLAKKYPVDRLKKTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NNV1</accession>
    <name>A0A1C7NNV1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Quinidine resistance protein 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">QDR2_0</name>
        <name evidence="9" type="ORF">A0J61_01139</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000033">
        <property type="protein sequence ID" value="OBZ90795.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NNV1"/>
    <dbReference type="STRING" id="101091.A0A1C7NNV1"/>
    <dbReference type="InParanoid" id="A0A1C7NNV1"/>
    <dbReference type="OrthoDB" id="440553at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd17323">
        <property type="entry name" value="MFS_Tpo1_MDR_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1720.10:FF:000009">
        <property type="entry name" value="MFS multidrug transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502:SF51">
        <property type="entry name" value="QUINIDINE RESISTANCE PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="81"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="117"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="148"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="177"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="209"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="236"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="391"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="424"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="485"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="508"/>
            <end position="531"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="543"/>
            <end position="564"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="576"/>
            <end position="599"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="8">
        <location>
            <begin position="82"/>
            <end position="600"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="42"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="276"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="303"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="279"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="311"/>
            <end position="325"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OBZ90795.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="615" mass="68560" checksum="554425805DC39304" modified="2016-11-30" version="1">MHSNTDSSNNYQHSHPESNTISNKSIDEKNLPSSTEIIAQSTENTLPEELSPTIASPKRHSTASSSFYEPYSVFSKNEKMVIVLIASISCFFSPFSANIYFPALTLIQEDMHITERMVSTTVTVYMILQGISPSFWGSLADSWGRRPVYISTFMIYTLACIGLAHTENYATLLSLRMLQAFGTSSAVAVGAGTIGDIASPIERGGYMGIYTMGSMLGSCLGPPLGGLLSYQLGWRWVFWVLAIMALGLWIVQIFCLPETLRSLVGNGTGYANPTPIQYWRHKKNQNKKNKTDQRQGIEEEMIEGSTASTKSNQLSDQSCLSLSSDTTAGNHSNSNKEIDEKQTYVSNSDSGILKPDCMDDLKINRQTQSDKKQWKFPNPFQSLTYLKEKDVAALLIYNSMQYASLYCVLTSLTSLFSDIYKLNVFQIGLCFLSGGLGATIGSFTSGKVLNWRFKKISNQMNLSEEYAKRAKIDPEFPIEKARMEITWIWGIIFNIFMIVYGWCLQQRVHIAIPLVINFILSYNSTCILNACNTLLVDCFPKNSAAIIAANNLTRCLLGAGAVMIVEPAISKLGVGWFFTMISLILFVSRISIVILLKFGPKWRLERLKRQQEAST</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NNV6</accession>
    <name>A0A1C7NNV6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Nucleoside diphosphate kinase</fullName>
            <ecNumber evidence="3">2.7.4.6</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">awd</name>
        <name evidence="10" type="ORF">A0J61_01282</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 7 8">Belongs to the NDK family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.4.6" evidence="3"/>
    <dbReference type="EMBL" id="LUGH01000038">
        <property type="protein sequence ID" value="OBZ90678.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NNV6"/>
    <dbReference type="STRING" id="101091.A0A1C7NNV6"/>
    <dbReference type="InParanoid" id="A0A1C7NNV6"/>
    <dbReference type="OrthoDB" id="2162449at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004550">
        <property type="term" value="F:nucleoside diphosphate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006241">
        <property type="term" value="P:CTP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006183">
        <property type="term" value="P:GTP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006228">
        <property type="term" value="P:UTP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04413">
        <property type="entry name" value="NDPk_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.141:FF:000002">
        <property type="entry name" value="Nucleoside diphosphate kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.141">
        <property type="entry name" value="Nucleoside diphosphate kinase-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00451">
        <property type="entry name" value="NDP_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034907">
        <property type="entry name" value="NDK-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036850">
        <property type="entry name" value="NDK-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001564">
        <property type="entry name" value="Nucleoside_diP_kinase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF001908">
        <property type="entry name" value="PRK00668.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11349">
        <property type="entry name" value="NUCLEOSIDE DIPHOSPHATE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00334">
        <property type="entry name" value="NDK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01243">
        <property type="entry name" value="NUCDPKINASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00562">
        <property type="entry name" value="NDK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54919">
        <property type="entry name" value="Nucleoside diphosphate kinase, NDK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51374">
        <property type="entry name" value="NDPK_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 10" id="KW-0418">Kinase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Nucleoside diphosphate kinase-like" evidence="9">
        <location>
            <begin position="75"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="active site" description="Pros-phosphohistidine intermediate" evidence="7">
        <location>
            <position position="190"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="83"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="131"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="160"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="166"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="177"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="187"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008142"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00017632"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00706"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU004011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00562"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OBZ90678.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="227" mass="24212" checksum="14ED138FBF7350B7" modified="2016-11-30" version="1">MFARAATRFAVRPAAASLKARTFATATRATAAAGSQRLALATAGVVTASALSYAYLQKPVSADSKPIAGVKGTPTERTFIAIKPDGVQRGLVGKIITRFEDKGYKLVGMKAIAPSKELAEKHYDDLKARPFFSGLVNYITSGTPVIAMVWQGPDVIRTGRVILGATDPLKADPSTIRGQYCVSVGRNIIHGSDSFESAEKEIGLWFPNAGELIDWTPANVDWVQSAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NP22</accession>
    <name>A0A1C7NP22_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Meiosis-specific transcription factor NDT80</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">NDT80_0</name>
        <name evidence="5" type="ORF">A0J61_01076</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000030">
        <property type="protein sequence ID" value="OBZ90872.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NP22"/>
    <dbReference type="STRING" id="101091.A0A1C7NP22"/>
    <dbReference type="InParanoid" id="A0A1C7NP22"/>
    <dbReference type="OrthoDB" id="2288358at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000228">
        <property type="term" value="C:nuclear chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051321">
        <property type="term" value="P:meiotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1390">
        <property type="entry name" value="NDT80 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052605">
        <property type="entry name" value="Fungal_trans_regulator"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024061">
        <property type="entry name" value="NDT80_DNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037141">
        <property type="entry name" value="NDT80_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008967">
        <property type="entry name" value="p53-like_TF_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35144">
        <property type="entry name" value="MEIOSIS-SPECIFIC TRANSCRIPTION FACTOR NDT80"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35144:SF2">
        <property type="entry name" value="MEIOSIS-SPECIFIC TRANSCRIPTION FACTOR NDT80"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05224">
        <property type="entry name" value="NDT80_PhoG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49417">
        <property type="entry name" value="p53-like transcription factors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51517">
        <property type="entry name" value="NDT80"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NDT80" evidence="4">
        <location>
            <begin position="93"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="NDT80" evidence="2">
        <location>
            <begin position="93"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="331"/>
            <end position="598"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="10"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="35"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="347"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="375"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="406"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="416"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="483"/>
            <end position="500"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="533"/>
            <end position="553"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="578"/>
            <end position="598"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OBZ90872.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="598" mass="67066" checksum="7EA9E6D5C3E7ECD3" modified="2016-11-30" version="1">MNSVHENKDWQGNNCQQPPLQTPPIALDSAASPKLSHSANAFPTSPANAYQQNNVYRAQSQQNMQQPYTPTETDPNARLPGMMAHSQPGTPCPENNNGNVTNLTSEPALYQQPPPFATRNVCRGRSNLFANETGPYFSSSKPFDNLYASDKQTLLSVRVQSKMDRGFFLADNDWTCYRRNYFQVSSVFSVHGFNHYYSINEPRVYVKSDEDGALYPVQRFLLGISARVANSEKEIDLIQHTPKRDKGPQFKPDPKPISPGGNLTMSSVANNQNIVTFERVQFKTATANNGKRRAAQQYYICITELYAETDRNQLVKVASCQSAPLVVRGRSPGHYADNQERHHPYAASSSAPINSVSDAMTSQPMTPQPTPPIHQENNNRQMMYNSYPKTPTQETSPMMQHGYDQPNPPPPPPPQVQQQQQQQQQQSSYSYYPAYPSYSHVQGQQPQQHQMAPSVSSPMSHPPMPSPYAHHPQVNYAVHDGNHSNPYGNEVYHNNSTPTTEEPKMPHHFHMQQTGPIESPHSGYDWQRARYNSSSSGSSSVPSPGGQQGEPQQAYFPHHHHPEGRPYSPTTPTYPPNMMQSRKYSSTVSNLMNKQQLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NP25</accession>
    <name>A0A1C7NP25_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Sec14 cytosolic factor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">sec14</name>
        <name evidence="2" type="ORF">A0J61_01326</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000040">
        <property type="protein sequence ID" value="OBZ90629.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NP25"/>
    <dbReference type="FunCoup" id="A0A1C7NP25">
        <property type="interactions" value="48"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NP25"/>
    <dbReference type="InParanoid" id="A0A1C7NP25"/>
    <dbReference type="OrthoDB" id="1434354at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00170">
        <property type="entry name" value="SEC14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.525.10">
        <property type="entry name" value="CRAL-TRIO lipid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001251">
        <property type="entry name" value="CRAL-TRIO_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036865">
        <property type="entry name" value="CRAL-TRIO_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036273">
        <property type="entry name" value="CRAL/TRIO_N_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051026">
        <property type="entry name" value="PI/PC_transfer"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45657">
        <property type="entry name" value="CRAL-TRIO DOMAIN-CONTAINING PROTEIN YKL091C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45657:SF1">
        <property type="entry name" value="CRAL-TRIO DOMAIN-CONTAINING PROTEIN YKL091C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00650">
        <property type="entry name" value="CRAL_TRIO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00516">
        <property type="entry name" value="SEC14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52087">
        <property type="entry name" value="CRAL/TRIO domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46938">
        <property type="entry name" value="CRAL/TRIO N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50191">
        <property type="entry name" value="CRAL_TRIO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CRAL-TRIO" evidence="1">
        <location>
            <begin position="122"/>
            <end position="284"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ90629.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="328" mass="37547" checksum="D197445D002C2A34" modified="2016-11-30" version="1">MHGSFKMAGTQLNEDQTRILEEFKVLLNDLDDNRKTNDNLLVQFLEANVWNKEEARNQLTKTIEWRKKFNVDKIPVATRQNKLPLLIACRGYKYIQDGNFAAQPEISESMIRIANCMGGGCFHKFDKDGHPILIDRTGYHNTKEMGYNVKTDEVSNFQIFVNEFLNRVIMPEGSERVGRPIHSETIIFDCTNMSLWQLHMSAFSHLRAIAEIVQNYYPETLHRLFVVNAPSAFVIMFKIIKPCLNARTLEKIHILGSDFRSVLLEYIDLENLPDFLGGTCQCQHMPGGCVPSISKEKFVPTNQNERVPTPYNTNIMEAAISDKSLSIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NP46</accession>
    <name>A0A1C7NP46_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Microphthalmia-associated transcription factor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">MITF_0</name>
        <name evidence="6" type="ORF">A0J61_01702</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000057">
        <property type="protein sequence ID" value="OBZ90236.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NP46"/>
    <dbReference type="FunCoup" id="A0A1C7NP46">
        <property type="interactions" value="1"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NP46"/>
    <dbReference type="InParanoid" id="A0A1C7NP46"/>
    <dbReference type="OrthoDB" id="690068at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.280.10">
        <property type="entry name" value="Helix-loop-helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011598">
        <property type="entry name" value="bHLH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036638">
        <property type="entry name" value="HLH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051732">
        <property type="entry name" value="USF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46117">
        <property type="entry name" value="FI24210P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46117:SF3">
        <property type="entry name" value="FI24210P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00010">
        <property type="entry name" value="HLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00353">
        <property type="entry name" value="HLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47459">
        <property type="entry name" value="HLH, helix-loop-helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50888">
        <property type="entry name" value="BHLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="BHLH" evidence="5">
        <location>
            <begin position="149"/>
            <end position="221"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50888"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OBZ90236.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="283" mass="32443" checksum="D0115AD13F3F6581" modified="2016-11-30" version="1">MYSPPQQDYGLDTDHFSQQQMGTPHTTVGAMPVVRNNRLFNPNYHHQRQNSFGTVASAITMSPPNNNHPHRNSMGFHDSNNSQNWFGTSMDSNGSSFGQSPIFTNMPRELVVSPSTSSSHLDTLTVASNHEEDEGQQKNLQEMFEKRRRRRESHNAVERRRRDNINERIHELCTLLPERLLDTAPTSSNVMSVSSGQVGANGRAINKGTILKLSVDHIKELREEVYRYQERIKELERMVEAAKHGELIQEAKPHFEDNTQKHHRMGSIQFRQQFNDLQIGTNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NPF8</accession>
    <name>A0A1C7NPF8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 13">GPI mannosyltransferase 1</fullName>
            <ecNumber evidence="13">2.4.1.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13">GPI mannosyltransferase I</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="primary">PIGM</name>
        <name evidence="14" type="ORF">A0J61_00969</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12 13">Mannosyltransferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers the first alpha-1,4-mannose to GlcN-acyl-PI during GPI precursor assembly. Required for cell wall integrity.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 13">Glycolipid biosynthesis; glycosylphosphatidylinositol-anchor biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 13">Endoplasmic reticulum membrane</location>
            <topology evidence="1 13">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 13">Belongs to the PIGM family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.-" evidence="13"/>
    <dbReference type="EMBL" id="LUGH01000026">
        <property type="protein sequence ID" value="OBZ90991.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NPF8"/>
    <dbReference type="FunCoup" id="A0A1C7NPF8">
        <property type="interactions" value="350"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NPF8"/>
    <dbReference type="InParanoid" id="A0A1C7NPF8"/>
    <dbReference type="OrthoDB" id="1741594at2759"/>
    <dbReference type="UniPathway" id="UPA00196"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990529">
        <property type="term" value="C:glycosylphosphatidylinositol-mannosyltransferase I complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0180041">
        <property type="term" value="F:dol-P-Man:GlcN-acyl-PI alpha-1,4-mannosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031505">
        <property type="term" value="P:fungal-type cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006506">
        <property type="term" value="P:GPI anchor biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007704">
        <property type="entry name" value="PIG-M"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12886:SF0">
        <property type="entry name" value="GPI MANNOSYLTRANSFERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12886">
        <property type="entry name" value="PIG-M MANNOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05007">
        <property type="entry name" value="Mannosyl_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 13" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="6 13 14" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="5 13" id="KW-0337">GPI-anchor biosynthesis</keyword>
    <keyword evidence="11 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 13 14" id="KW-0808">Transferase</keyword>
    <keyword evidence="8 13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10 13" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="83"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="160"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="207"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="275"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="299"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="344"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="375"/>
            <end position="396"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013797"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00025399"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU365064"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="OBZ90991.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="424" mass="49493" checksum="6AFC7FC831CACFB7" modified="2016-11-30" version="1">MAKKFMNTFLTFKHLCVSALVLRLILLAYGEYQDAYFTVKYTDIDYVVFTDAARYITQGQSPYLRDTYRYTPLLAMLMTPNIYWFYSFGKCLFALSDLVVGYLIHQILVMRGMPSRSALKYDALWLLNPMVANISTRGNAESLLGVMVLGTLYLILTKRFFSGCCLFGLAVHFKIYPVIYAVPLLVLLDEQVYRLPYLYFFSRHSSYGWITPLRILFGLTSGLVFFVLTGLMYQSYGQPFLQHTYLYHVTRQDHRHNFSLWFYQMYLTIHQSHSWMGLLAFIPQLGLVTWIGIGFGKDVLFACFLQTFLFVTFNKVITSQYFMWYICLFPLVLPSSRIKFRWKGLSMLIAWAAGQACWLYYAYGLEFLGQNTFLSLWAAGVVFFVINCWIIVEFIYQHHYEPIYGSSGRVRWVWGMGDPGTKRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NPW1</accession>
    <name>A0A1C7NPW1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Methionine aminopeptidase</fullName>
            <ecNumber evidence="6">3.4.11.18</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">METAP1</name>
        <name evidence="8" type="ORF">A0J61_00866</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Cotranslationally removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5 6">
            <text>Release of N-terminal amino acids, preferentially methionine, from peptides and arylamides.</text>
            <dbReference type="EC" id="3.4.11.18"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>Co(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:48828"/>
        </cofactor>
        <cofactor evidence="5">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <cofactor evidence="5">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <cofactor evidence="5">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
        <text evidence="5">Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.11.18" evidence="6"/>
    <dbReference type="EMBL" id="LUGH01000023">
        <property type="protein sequence ID" value="OBZ91068.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NPW1"/>
    <dbReference type="FunCoup" id="A0A1C7NPW1">
        <property type="interactions" value="705"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NPW1"/>
    <dbReference type="InParanoid" id="A0A1C7NPW1"/>
    <dbReference type="OrthoDB" id="3209743at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004239">
        <property type="term" value="F:initiator methionyl aminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070006">
        <property type="term" value="F:metalloaminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01086">
        <property type="entry name" value="MetAP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.230.10">
        <property type="entry name" value="Creatinase/methionine aminopeptidase superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01974">
        <property type="entry name" value="MetAP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036005">
        <property type="entry name" value="Creatinase/aminopeptidase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000994">
        <property type="entry name" value="Pept_M24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001714">
        <property type="entry name" value="Pept_M24_MAP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002467">
        <property type="entry name" value="Pept_M24A_MAP1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00500">
        <property type="entry name" value="met_pdase_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43330">
        <property type="entry name" value="METHIONINE AMINOPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43330:SF7">
        <property type="entry name" value="METHIONINE AMINOPEPTIDASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00557">
        <property type="entry name" value="Peptidase_M24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00599">
        <property type="entry name" value="MAPEPTIDASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55920">
        <property type="entry name" value="Creatinase/aminopeptidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00680">
        <property type="entry name" value="MAP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 5 6" id="KW-0031">Aminopeptidase</keyword>
    <keyword evidence="4 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 5 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2 5 6" id="KW-0645">Protease</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase M24" evidence="7">
        <location>
            <begin position="4"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="42"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="59"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="70"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>2</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="70"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="133"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>2</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="140"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="166"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>2</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="197"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>2</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="197"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>1</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03174"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003653"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OBZ91068.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="212" mass="23793" checksum="1D8869EE37E7246C" modified="2016-11-30" version="1">MFKKIDEIIHKATIDRGAYPSPLNYYKFPKSVCISVNEVICHGIPDKRALKEGDIVNLDISCYYNGFHGDMNATYCVGKVDEKGVQLVNTARECLEKAIAMVKPGIRYRDFGKVIEEHAKKNGFSVNRTFSGHGINQLFHCAPNVPHYANNKAIGIVKPGHCFTIEPMICEGGWRDEIWPDDWTAVTSDGKRSAQFEHTLLVTEDGCEILTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NPZ1</accession>
    <name>A0A1C7NPZ1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Pheromone-regulated membrane protein 10</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">A0J61_00983</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the ThrE exporter (TC 2.A.79) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000026">
        <property type="protein sequence ID" value="OBZ90969.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NPZ1"/>
    <dbReference type="FunCoup" id="A0A1C7NPZ1">
        <property type="interactions" value="4"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NPZ1"/>
    <dbReference type="InParanoid" id="A0A1C7NPZ1"/>
    <dbReference type="OrthoDB" id="413008at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010619">
        <property type="entry name" value="ThrE-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051361">
        <property type="entry name" value="ThrE/Ser_Exporter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024528">
        <property type="entry name" value="ThrE_2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31082">
        <property type="entry name" value="PHEROMONE-REGULATED MEMBRANE PROTEIN 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31082:SF4">
        <property type="entry name" value="PHEROMONE-REGULATED MEMBRANE PROTEIN 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06738">
        <property type="entry name" value="ThrE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12821">
        <property type="entry name" value="ThrE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="290"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="315"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="352"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="399"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="442"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="489"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="517"/>
            <end position="533"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="553"/>
            <end position="576"/>
        </location>
    </feature>
    <feature type="domain" description="Threonine/serine exporter-like N-terminal" evidence="7">
        <location>
            <begin position="183"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="domain" description="Threonine/Serine exporter ThrE" evidence="8">
        <location>
            <begin position="446"/>
            <end position="573"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00034125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF06738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF12821"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OBZ90969.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="588" mass="64164" checksum="624ADE0BCBF2F864" modified="2016-11-30" version="1">MEGNKFHDPETPPPIDLSAIHPVFSRHQEDLETEKHEIVSNPIEMSSNETEGPSHTDQAFHLVNSVTRENVRRRPSKAGILSNLLKLDVFEDHLRHPQTRQGGRPSRSLHQLHSIASNRAFLQSKPVSPNDPSSGQNSVYQDETTVHSMAELGMLNDKDVPAIAAHRMAIASEIADILHRQEVIIKMGKCLVRTGAPSHRIEAAMDKVSKRLEIDGSYAVLPGLIVVTFGDVETHTSETHLIRCSRSLDINKLEKSNLIAHKLAKGELDLDEASKRLDDIIHSPPTWSPAWLMLGYIGSSAFVAPLFFNGSWTDCWVSAIFGLCVGILTYISEKMPMFGNVFEMAITIPIAIIALALHSYVCFAAIALSAIVIALPGYSLTCSVMELAAKNLVSGTVHLVYALMYILFLAFGIGYGCSVWRLAYPELDLNVLGTCEDGINPYWTFLLLPLAIMAIGLVYGAHYRQWPSMIADSAIAYAVYYFVSKYVGSTNVIAPSAGAFALGLAGNIYARVTRRQAFAPLMSGTLILVPGSLGVRGAVHLFDGSNNGSGSEFVFQILGIALSITLGLFLANLVVYPTGKKRSVFLGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NQD3</accession>
    <name>A0A1C7NQD3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">A0J61_00657</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Ornithine decarboxylase (ODC) antizyme protein that negatively regulates ODC activity and intracellular polyamine biosynthesis in response to increased intracellular polyamine levels. Binds to ODC monomers, inhibiting the assembly of the functional ODC homodimer, and targets the monomers for ubiquitin-independent proteolytic destruction by the 26S proteasome.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Interacts with ODC and thereby sterically blocks ODC homodimerization.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ODC antizyme family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000015">
        <property type="protein sequence ID" value="OBZ91312.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NQD3"/>
    <dbReference type="InParanoid" id="A0A1C7NQD3"/>
    <dbReference type="OrthoDB" id="5959761at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008073">
        <property type="term" value="F:ornithine decarboxylase inhibitor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0075523">
        <property type="term" value="P:viral translational frameshifting"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002993">
        <property type="entry name" value="ODC_AZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038581">
        <property type="entry name" value="ODC_AZ_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02100">
        <property type="entry name" value="ODC_AZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0688">Ribosomal frameshifting</keyword>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002307"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008796"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011486"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022758"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OBZ91312.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="63" mass="7198" checksum="F02947D8A7F2E07C" modified="2016-11-30" version="1" fragment="single">ITHLIELAEEKTGCHALVVSIDKHEYKESLSTILRAFMYLGFEMVDPCVYGQEPGYILVGYEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NR21</accession>
    <name>A0A1C7NR21_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Phosphatidylinositide phosphatase SAC1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">Sac1</name>
        <name evidence="3" type="ORF">A0J61_00398</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000008">
        <property type="protein sequence ID" value="OBZ91577.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NR21"/>
    <dbReference type="FunCoup" id="A0A1C7NR21">
        <property type="interactions" value="1235"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NR21"/>
    <dbReference type="InParanoid" id="A0A1C7NR21"/>
    <dbReference type="OrthoDB" id="405996at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043812">
        <property type="term" value="F:phosphatidylinositol-4-phosphate phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046856">
        <property type="term" value="P:phosphatidylinositol dephosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002013">
        <property type="entry name" value="SAC_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45662">
        <property type="entry name" value="PHOSPHATIDYLINOSITIDE PHOSPHATASE SAC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45662:SF2">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL-3-PHOSPHATASE SAC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02383">
        <property type="entry name" value="Syja_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50275">
        <property type="entry name" value="SAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="520"/>
            <end position="537"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="549"/>
            <end position="569"/>
        </location>
    </feature>
    <feature type="domain" description="SAC" evidence="2">
        <location>
            <begin position="116"/>
            <end position="445"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50275"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ91577.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="612" mass="70761" checksum="E01C054529745E85" modified="2016-11-30" version="1">MYKDLKLYITNQSYVLSPTTGASLVIQRETGQVELSDIVPSASEQEIVLDVYGILGFIKLLAGEYLLTITKREKVGSIQDKVIYRVGAFQILPLPHNMNKLNEERRAQEQKYVSLLEQHLKNNTFYFSYDYDLTQSVQRQAQLMNPNEPLYKRADERFFWNRFISSKLIDASVDLSSFVLPVLQGFVELESVEVNNKKFEWGLITRRSRHRSGTRYFSRGIDDQGHVSNFVETEQLVLYTDSILSYVQTRGSIPVYWAQVINLKYTPRLWIGESKKNLAAARAHFDEQIRLYGPQILVNLINKKGYELPMGQAYARTVEQLNDPRIYYTHFDFHSECSKMRWHRIQLLVDQLKDKLVEQSYTYYNIADKSLKKTQTSVVRSNCMDCLDRTNVVQSTLARYVLTNQLRELGILESNQNLEDQEKFMHSYRNVWADNADGVSCVYSGTGALKTDFTRTGQRTKQGALKDLHNSITRYIKNNFLDGNRQDAFDLVLGNFDVHRDQPASAQRANYAEQPLRVRVVPYILAFALFMLLVNLVRPSYSGFQSYTAYFLLLLFWVSVLISGVRFALKHGDDFVQWPDLVKLPSYDDVFEVGFTKKGSMAPPEITKDEII</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NRW6</accession>
    <name>A0A1C7NRW6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_00094</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000002">
        <property type="protein sequence ID" value="OBZ91865.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NRW6"/>
    <dbReference type="InParanoid" id="A0A1C7NRW6"/>
    <dbReference type="OrthoDB" id="5563272at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ91865.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="67" mass="7709" checksum="71738EEBFF7CEF5C" modified="2016-11-30" version="1">MFQKIVNFWFSSFITERLLASPIFNRMAAKTHQHVSTITDKGTKASGDFMKAFRENLEKEARKNAGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-06-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NTY0</accession>
    <name>A0A1C7NTY0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_01013</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000027">
        <property type="protein sequence ID" value="OBZ90954.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NTY0"/>
    <dbReference type="InParanoid" id="A0A1C7NTY0"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ90954.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="86" mass="10252" checksum="19A71945701BCBD1" modified="2016-11-30" version="1">MRINSSPPFELCKRVSLSKKRDIVRRHSQQARIAKRSEYLLTVRSEAYQNPNDQQRLKCEVLYVLIEIRIRAENNNFTCTTTRLQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7LLR0</accession>
    <name>A0A1C7LLR0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_11968</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01002787">
        <property type="protein sequence ID" value="OBZ63522.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="InParanoid" id="A0A1C7LLR0"/>
    <dbReference type="OrthoDB" id="2296184at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="123"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ63522.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="123" mass="14124" checksum="B56F69AE9D8E1F78" modified="2016-11-30" version="1" fragment="single">MKEAFGEELLKQFRKEKRLLLFDDVLLEYDENRDKDELEESLFMLKKKASGATARTLKTIMLLLDHMSEKKSAMSEMRLQSGIVTALCHMFKPNTSHDVVGYNKVLFPASVAAKNCRXDIIVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-06-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7LN12</accession>
    <name>A0A1C7LN12_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_11935</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01002727">
        <property type="protein sequence ID" value="OBZ65337.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7LN12"/>
    <dbReference type="InParanoid" id="A0A1C7LN12"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ65337.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="58" mass="6758" checksum="413D2FFFDFD0796E" modified="2016-11-30" version="1" fragment="single">IPFEYFVKQLESGYIFLSSTMESIISVFFGVCFPHTVEYNKEDGIEKFYMAVYEPSKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MTF1</accession>
    <name>A0A1C7MTF1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_11819</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01002535">
        <property type="protein sequence ID" value="OBZ80132.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MTF1"/>
    <dbReference type="InParanoid" id="A0A1C7MTF1"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="16"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="37"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ80132.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="79" mass="8833" checksum="F43A08D9602D4E56" modified="2016-11-30" version="1" fragment="single">MPSSEGSTQRTEEYESVQNIDTTRLTEGEVTDDSLIAKRKRGNSSKKATKSKKTPNRAHMVLWNSLPLELIKNSGLDNI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MTI2</accession>
    <name>A0A1C7MTI2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_11770</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01002458">
        <property type="protein sequence ID" value="OBZ80181.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MTI2"/>
    <dbReference type="InParanoid" id="A0A1C7MTI2"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="40"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ80181.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="40" mass="4687" checksum="5D784B6686676A89" modified="2016-11-30" version="1" fragment="single">MRSFDSATKDECSHWYNMFNRSAAEFGIEVEKGKAEQAWE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MTV4</accession>
    <name>A0A1C7MTV4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_11764</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01002452">
        <property type="protein sequence ID" value="OBZ80187.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MTV4"/>
    <dbReference type="InParanoid" id="A0A1C7MTV4"/>
    <dbReference type="OrthoDB" id="2216067at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008889308" evidence="1">
        <location>
            <begin position="24"/>
            <end position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ80187.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="66" mass="7568" checksum="19F7B429551ABEC4" modified="2016-11-30" version="1">MSTIVLSMLLFMASILLSLKVHGTISNYVVPRSRNKKIMPWVLIEFIWRRKHCGDITGGIVKVLKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MUJ5</accession>
    <name>A0A1C7MUJ5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_11395</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001987">
        <property type="protein sequence ID" value="OBZ80555.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MUJ5"/>
    <dbReference type="InParanoid" id="A0A1C7MUJ5"/>
    <dbReference type="OrthoDB" id="2289822at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ80555.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="129" mass="14743" checksum="075900241C2B957A" modified="2016-11-30" version="1" fragment="single">KTYNSILNQNGLVRARRTREAEYEDDPDDEEGVLSQLWKKFQQAVLNDGIEIANVSIIGIRQAMEKYFGRLSGGSTSLDNNSVKWAARVMIDGIVIQSRWHRGNQKNVKRADNLVIFEAKESIRSRNFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MUK3</accession>
    <name>A0A1C7MUK3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_11420</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01002014">
        <property type="protein sequence ID" value="OBZ80531.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MUK3"/>
    <dbReference type="STRING" id="101091.A0A1C7MUK3"/>
    <dbReference type="InParanoid" id="A0A1C7MUK3"/>
    <dbReference type="OrthoDB" id="2287304at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006912">
        <property type="entry name" value="Harbinger_derived_prot"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47150:SF7">
        <property type="entry name" value="NUCLEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47150">
        <property type="entry name" value="OS12G0169200 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04827">
        <property type="entry name" value="Plant_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ80531.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="209" mass="24584" checksum="1C94E6E888038724" modified="2016-11-30" version="1">MSETLFDFGITVINKRKREFEEESTKRTGSVFGKRFIQRDRVELDQKLNEDYFNDRCRFPDKLFERRFRIVLKADAKFALLKDAQCLPEASTRQKVASGIRLPDKGSVFDAMNKYFGISESSSADYFVRFLKVIIKSFGNEYLRKSNTDDVKRLLVWEEMRGFPGILSSLDCMHWEWESFPSSWKGQYLNRKSNTTMVLKAVASYDLWI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MUY6</accession>
    <name>A0A1C7MUY6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Tyr recombinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_11384</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001975">
        <property type="protein sequence ID" value="OBZ80567.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MUY6"/>
    <dbReference type="STRING" id="101091.A0A1C7MUY6"/>
    <dbReference type="InParanoid" id="A0A1C7MUY6"/>
    <dbReference type="OrthoDB" id="2221171at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015074">
        <property type="term" value="P:DNA integration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.443.10">
        <property type="entry name" value="Intergrase catalytic core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011010">
        <property type="entry name" value="DNA_brk_join_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013762">
        <property type="entry name" value="Integrase-like_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010998">
        <property type="entry name" value="Integrase_recombinase_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35617:SF3">
        <property type="entry name" value="CORE-BINDING (CB) DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35617">
        <property type="entry name" value="PHAGE_INTEGRASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56349">
        <property type="entry name" value="DNA breaking-rejoining enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47823">
        <property type="entry name" value="lambda integrase-like, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="498"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ80567.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="498" mass="55278" checksum="DA105E8E21DD9CCD" modified="2016-11-30" version="1" fragment="single">TTTTVVRINDSQEDVPAHTTPVGATENRRICSSPQPPTAHVLVPISGSSSIRNRCHATDMVEEGNVSIPSLEVDSAGVEENTRAEIEASCSDHSVVAQSVLVPHDSAHETHSASTGLEDQSEMVSSRLEIINHYRAQDGITEDTVQYLTQKTRQSTHKAYGNGWRHWHLWCKQQHPPCEPLNYDVKTILQFLQDNKDFSSTHLNTLRSSIASVFSVIHSDKPPIAEQSLIKDFFAAKRNSEVRIPTEQQSATWDISILVIYIKQHLSPTSTLSLDQLQLKTVLLLCISIMWRPRSDIGRLQYRDIVLKRDGLASSIRIHARSPKESQVKSVTLGAIEDEDLCPVKTTYSFVTKTAHLRESLPDDHTLFLAYIDSPQKLPMSVRPTTVANWVKEALGKAGVNTKDYQAHSVRAASSTKAVELGHSIQEVKKHANWSLNSNTFENFYYKPSSQTSSSTAITNSIFSSPEKRITLEAEVESTGISLGTTTNTNVDETKAKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MUZ0</accession>
    <name>A0A1C7MUZ0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_11705</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01002369">
        <property type="protein sequence ID" value="OBZ80246.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MUZ0"/>
    <dbReference type="InParanoid" id="A0A1C7MUZ0"/>
    <dbReference type="OrthoDB" id="2276859at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ80246.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="317" mass="36595" checksum="04765D7DFB90BCB5" modified="2016-11-30" version="1" fragment="single">NMKERKIAANRNCIYDLSNSGPSGQSTVEFVNVKNKAKRIETPLPELPEDVKTSIINNFKKGVNLNIMFNNMTKNIIQSTSSNRVYFKLLAHIVESHQLSPDIFVISKLPEFSEMDISFQFWSRIFHLIFSSSSTLKIKSGEKKLESSSFKIDYKIGCNIKGKFMTLSCVEIGRFVNDAKVRDDHHKLLLEGKVIINNIIKNFPFIDPNCIAIFNLQICGMKGDFIETILGNKKKYIAHRPLDRLRAPLHRNNNKIIDTFLRQLMYYKNYVETLCHDIEQMVNENDDKSASFGETLDTNTFKPPNFLDWIDDNVERL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MV04</accession>
    <name>A0A1C7MV04_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Replication protein A subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">ssb1_1</name>
        <name evidence="12" type="ORF">A0J61_11279</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">As part of the replication protein A (RPA/RP-A), a single-stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Component of the heterotrimeric canonical replication protein A complex (RPA).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the replication factor A protein 1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001861">
        <property type="protein sequence ID" value="OBZ80672.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MV04"/>
    <dbReference type="FunCoup" id="A0A1C7MV04">
        <property type="interactions" value="844"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7MV04"/>
    <dbReference type="InParanoid" id="A0A1C7MV04"/>
    <dbReference type="OrthoDB" id="1751331at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000781">
        <property type="term" value="C:chromosome, telomeric region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005662">
        <property type="term" value="C:DNA replication factor A complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007004">
        <property type="term" value="P:telomere maintenance via telomerase"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd04474">
        <property type="entry name" value="RPA1_DBD_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd04475">
        <property type="entry name" value="RPA1_DBD_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd04476">
        <property type="entry name" value="RPA1_DBD_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.140:FF:000041">
        <property type="entry name" value="Replication protein A subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.140:FF:000064">
        <property type="entry name" value="Replication protein A subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.140:FF:000090">
        <property type="entry name" value="Replication protein A subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047192">
        <property type="entry name" value="Euk_RPA1_DBD_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013955">
        <property type="entry name" value="Rep_factor-A_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031657">
        <property type="entry name" value="REPA_OB_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004591">
        <property type="entry name" value="Rfa1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00617">
        <property type="entry name" value="rpa1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47165">
        <property type="entry name" value="OS03G0429900 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47165:SF4">
        <property type="entry name" value="OS03G0429900 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08646">
        <property type="entry name" value="Rep_fac-A_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16900">
        <property type="entry name" value="REPA_OB_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 9" id="KW-0235">DNA replication</keyword>
    <keyword evidence="7 9" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8 9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 9" id="KW-0862">Zinc</keyword>
    <keyword evidence="5 9" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Replication protein A OB" evidence="11">
        <location>
            <begin position="81"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="domain" description="Replication factor A C-terminal" evidence="10">
        <location>
            <begin position="240"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="12">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005690"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU364130"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF08646"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF16900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="OBZ80672.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="391" mass="43830" checksum="3C6B25ADEA1A2285" modified="2016-11-30" version="1" fragment="single">NLLDQTGEIKATAFGDQVTRLYHVLEEGKVYYISKARVTMARKQFSNLNNEYELGLEPNTEIEACPEPGNIPMMNFDFVKIGDLVKREANSYVDVLGVVTEDAGLSEIISKATGKPTKKRDLTIADDSGKSVRLTLWDPKDDGFETSANPIIACKGARVSDFNGRALSASSGCLIKVNPDIPEMQKLRRWYNEKGQNSQFDSFSNAMTVGGNGEYRGNSNRITLQEAKTQNLGSSDRPDYFSFRGTVVFIKNENFAYPSCPTCRKKTLLEETGWRCEKCQKSFPKPEYRYILTMSVEDATSQIYLNGFDDLGLAVLKTSANDLMELKETNGTAAHQIIAKAHYQTFNFKVRAKQEVFNDIARTKFQCVDVQPIDYVKESQELAAAIDQILE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MVJ2</accession>
    <name>A0A1C7MVJ2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">WH2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_11515</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01002137">
        <property type="protein sequence ID" value="OBZ80436.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MVJ2"/>
    <dbReference type="STRING" id="101091.A0A1C7MVJ2"/>
    <dbReference type="InParanoid" id="A0A1C7MVJ2"/>
    <dbReference type="OrthoDB" id="2290654at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003779">
        <property type="term" value="F:actin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.280.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003124">
        <property type="entry name" value="WH2_dom"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51082">
        <property type="entry name" value="WH2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="WH2" evidence="1">
        <location>
            <begin position="14"/>
            <end position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ80436.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="92" mass="9500" checksum="087365F11129BDBC" modified="2016-11-30" version="1">MSSTPSNLPLVDDGRSNLMASIRAAGGFGTLKQSGKLKKADTIHDRSATTTLAAGAAGAAGGTLASSLADVLKQRKQAIHSDDEDDDDDEWE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MW44</accession>
    <name>A0A1C7MW44_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transposable element Tcb2 transposase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">TCB2</name>
        <name evidence="3" type="ORF">A0J61_11302</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001885">
        <property type="protein sequence ID" value="OBZ80649.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MW44"/>
    <dbReference type="STRING" id="101091.A0A1C7MW44"/>
    <dbReference type="InParanoid" id="A0A1C7MW44"/>
    <dbReference type="OrthoDB" id="2416077at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015074">
        <property type="term" value="P:DNA integration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006313">
        <property type="term" value="P:DNA transposition"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038717">
        <property type="entry name" value="Tc1-like_DDE_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052338">
        <property type="entry name" value="Transposase_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002492">
        <property type="entry name" value="Transposase_Tc1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23022:SF135">
        <property type="entry name" value="SI:DKEY-77F5.3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23022">
        <property type="entry name" value="TRANSPOSABLE ELEMENT-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13358">
        <property type="entry name" value="DDE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01498">
        <property type="entry name" value="HTH_Tnp_Tc3_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Transposase Tc1-like" evidence="1">
        <location>
            <begin position="86"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="domain" description="Tc1-like transposase DDE" evidence="2">
        <location>
            <begin position="143"/>
            <end position="277"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01498"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13358"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ80649.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="277" mass="31766" checksum="A3C5BF91497EA935" modified="2016-11-30" version="1">MPSHVSNDKRNDAKAMLLHGKIVREVASALGISKSTVSNIRRECDVDMRQQKGGRPAKMSKYLERKVLQGINTGTSLNAKDARRYLADNQVVISSDTVRRLLKRANLEAFLKPDVLPLTPKRKKDRLNWAKSRQNWTINDWKRLVFSDETKINRLGSDGAQWTSKAVNEELKDFQLNHLYKHGGGSINVWSCFCWKSPGYLTKIEGRMDSDLYIEILDDELIKTLDYYGYSEDTVIFQQDIDPKHTAKKTLKHLEDCGIEVIDWPAYSPDLNPIENL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MX73</accession>
    <name>A0A1C7MX73_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Reverse transcriptase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_10538</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001224">
        <property type="protein sequence ID" value="OBZ81413.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MX73"/>
    <dbReference type="InParanoid" id="A0A1C7MX73"/>
    <dbReference type="OrthoDB" id="2278241at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="324"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ81413.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="324" mass="37318" checksum="D76AC2C60F835F12" modified="2016-11-30" version="1" fragment="single">MIASIRFTSRKFFKLSVSPPESRHIITKLFFSANLVVNSSECLDRVNLPPTNKLLAYADDVLIFLNSVEEFQTLQVLLSTYNSAFNSKINYHKSVAFPLSGSSNSQADLRQADLRQAFRLRTDCTHPNVLTKLKRALGSGQLEFAPFFAHHMLNPIDVRVEDSPPLNLCQLNNPMINAASWRSFIQTPMLAPIRNVWFRLIHQKISNRVYMHQIMPRTMDDDLCTLCQQPEPANHLMFLYPHKELVWTEAFEGYFRQSNNINRIAKDIIHLRLSNYVIKAPDRITIYDAMGAILFGVWCAHWQLHFEGVPFEPIPIANHLPKQI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MXC2</accession>
    <name>A0A1C7MXC2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Heat shock protein 12B</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">Hspa12b_3</name>
        <name evidence="3" type="ORF">A0J61_10490</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001199">
        <property type="protein sequence ID" value="OBZ81460.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MXC2"/>
    <dbReference type="STRING" id="101091.A0A1C7MXC2"/>
    <dbReference type="InParanoid" id="A0A1C7MXC2"/>
    <dbReference type="OrthoDB" id="2218269at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013126">
        <property type="entry name" value="Hsp_70_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14187">
        <property type="entry name" value="ALPHA KINASE/ELONGATION FACTOR 2 KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14187:SF5">
        <property type="entry name" value="HEAT SHOCK 70 KDA PROTEIN 12A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00012">
        <property type="entry name" value="HSP70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0346">Stress response</keyword>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="270"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ81460.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="270" mass="30665" checksum="95410F424237A8E1" modified="2016-11-30" version="1" fragment="single">MNTGIRTFNPNDYPVVIGIDFGTTFSGCAYAYTQNEEVVDIVRCNSSQMTQWGNAARVEMQRPTARNSVLLKQYKLYLDENIARDLPPLPNGLTIVDAIADYLKAFHEHVVNELKKGFARNYGQHQFRYCLTVPAMWSDRAKNTMRDAAIKAGLIDETDHRDRLMLISEPEAAALYCEKKCEQFNLRHGDKFMICDAGGGTVDLIVFEIDEHSGRKLKESTKGHGQSCGSVFLDRRMRKLLKKKFKEYLSSIPASAFETMMDTFVDLIKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MXC4</accession>
    <name>A0A1C7MXC4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_10487</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001197">
        <property type="protein sequence ID" value="OBZ81463.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MXC4"/>
    <dbReference type="InParanoid" id="A0A1C7MXC4"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="11"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ81463.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="132" mass="14890" checksum="8CF41AFFCCB29963" modified="2016-11-30" version="1">MFTALTLADRFMNEDDKNDKNDKDFDPMSESEDGSELSRSKINPGEVDAVSHQEKNLMLSETRKDIEQVLASALEAKKTYIKQIQHLKSYPAGVELIATESEILDQFTKKLDLVEKSLENITNQEHNGASSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-06-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MXQ8</accession>
    <name>A0A1C7MXQ8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_10337</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001124">
        <property type="protein sequence ID" value="OBZ81610.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MXQ8"/>
    <dbReference type="InParanoid" id="A0A1C7MXQ8"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ81610.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="121" mass="13915" checksum="85E5817D11CCCA8B" modified="2016-11-30" version="1">MSDKYVRCYCSECKENSQGYNVLTKRTYQERERVEISKKIKETCELELNQQPSTVDVNDEIDGFDDADDMSFGTCSDNDTDAFETEQRAMEYLLNPAQNVHLPKSPVASLLFALLVLMRKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MXW2</accession>
    <name>A0A1C7MXW2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Exocyst complex component 6B</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">EXOC6B</name>
        <name evidence="2" type="ORF">A0J61_10350</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001130">
        <property type="protein sequence ID" value="OBZ81601.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MXW2"/>
    <dbReference type="STRING" id="101091.A0A1C7MXW2"/>
    <dbReference type="InParanoid" id="A0A1C7MXW2"/>
    <dbReference type="OrthoDB" id="10267033at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000145">
        <property type="term" value="C:exocyst"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006893">
        <property type="term" value="P:Golgi to plasma membrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090522">
        <property type="term" value="P:vesicle tethering involved in exocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007225">
        <property type="entry name" value="EXOC6/Sec15"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048359">
        <property type="entry name" value="EXOC6_Sec15_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12702:SF0">
        <property type="entry name" value="EXOCYST COMPLEX COMPONENT 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12702">
        <property type="entry name" value="SEC15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20651">
        <property type="entry name" value="EXOC6_Sec15_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Exocyst complex component EXOC6/Sec15 N-terminal" evidence="1">
        <location>
            <begin position="70"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="318"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF20651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ81601.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="318" mass="36314" checksum="0847B9DD861B2A2E" modified="2016-11-30" version="1" fragment="single">MPTTAADDPELGRLASSLEKTSVNETSVSASGFELTFSATLDDAENLEQLGPVIKHITQTGKQTVFLDALDALIRKKDGEIERMCNSHYQEFVHAVDQLLKVRQGSVELKRKLADVNQALQSRGARWAEKKRELTNARKVQQNVDDAIEALQSCLVVLESANKVNDQLEKKRYYAALKILDSLESDRLGETIQYTFTKMLVQSVPVMQNTIKSTVTVELKEWLARVREISREIGLLAMQRMQERQERWRSKTTENPKLKNLQHHQVNSAIEMVVNEGLETSILDEVNIDFEPLYKCIHVHDTLGKRNEFKTSYSEDRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MXW6</accession>
    <name>A0A1C7MXW6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_10724</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001341">
        <property type="protein sequence ID" value="OBZ81229.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MXW6"/>
    <dbReference type="InParanoid" id="A0A1C7MXW6"/>
    <dbReference type="OrthoDB" id="2288941at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="191"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ81229.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="191" mass="21788" checksum="B3DC7219132C66F0" modified="2016-11-30" version="1" fragment="single">TKAQSLTADLRIEGERVSLEDNSRALFNKYPKGKQTKRALPSPVVYDIKGDLKSTTREKVALEREVERIVQLPKIKFSRKDIMKNNQSSTVIPLPKGLNAKQVTGHFNPLPDGNCEHRVTAYTVSEDKHIYGKVKNEMLTCLKKNEHLCHQVFDSSLLPTFIVLSDTYKDVYNKFNNDASNGTIDNWFQFT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MY95</accession>
    <name>A0A1C7MY95_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">54S ribosomal protein L16, mitochondrial</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">mrpl16_1</name>
        <name evidence="7" type="synonym">mrpl16_0</name>
        <name evidence="7" type="ORF">A0J61_04845</name>
        <name evidence="6" type="ORF">A0J61_10575</name>
    </gene>
    <organism evidence="6 8">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 8" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the universal ribosomal protein uL16 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001244">
        <property type="protein sequence ID" value="OBZ81376.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="LUGH01000247">
        <property type="protein sequence ID" value="OBZ87103.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MY95"/>
    <dbReference type="FunCoup" id="A0A1C7MY95">
        <property type="interactions" value="50"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7MY95"/>
    <dbReference type="InParanoid" id="A0A1C7MY95"/>
    <dbReference type="OrthoDB" id="268521at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005762">
        <property type="term" value="C:mitochondrial large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032543">
        <property type="term" value="P:mitochondrial translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01433">
        <property type="entry name" value="Ribosomal_L16_L10e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1170.10">
        <property type="entry name" value="Ribosomal protein L10e/L16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047873">
        <property type="entry name" value="Ribosomal_uL16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000114">
        <property type="entry name" value="Ribosomal_uL16_bact-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020798">
        <property type="entry name" value="Ribosomal_uL16_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016180">
        <property type="entry name" value="Ribosomal_uL16_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036920">
        <property type="entry name" value="Ribosomal_uL16_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01164">
        <property type="entry name" value="rplP_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12220">
        <property type="entry name" value="50S/60S RIBOSOMAL PROTEIN L16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12220:SF13">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN UL16M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00252">
        <property type="entry name" value="Ribosomal_L16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00060">
        <property type="entry name" value="RIBOSOMALL16"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54686">
        <property type="entry name" value="Ribosomal protein L16p/L10e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00701">
        <property type="entry name" value="RIBOSOMAL_L16_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 6" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="194"/>
            <end position="214"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU004413"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OBZ81376.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OBZ87103.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="214" mass="23458" checksum="36495AFE674D94E2" modified="2016-11-30" version="1">MFSALKKSALSTIHSTSNVISNVFLQQHTKTAAITQSVRFASNFSPKRTKYRKAHKGRIPIPVGGSTKGTTVEFGDYGLRVKEGVRLTARQLTAVHNALRRKIKPVKGSQMWMRVFPDIPVSSKGNEVRMGKGKGTFEYWACRVPLNRIIFEIAGMRKEIAKEAFRLASHKLPVKVEMVERGAKPIVGAGYVPSAKPTTTTTTAAKDTTPSSSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MYA4</accession>
    <name>A0A1C7MYA4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Reticulocyte-binding protein 2 a</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_10192</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001065">
        <property type="protein sequence ID" value="OBZ81761.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MYA4"/>
    <dbReference type="STRING" id="101091.A0A1C7MYA4"/>
    <dbReference type="InParanoid" id="A0A1C7MYA4"/>
    <dbReference type="OrthoDB" id="2406983at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051425">
        <property type="entry name" value="Formin_Homology"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45725:SF20">
        <property type="entry name" value="C3H1-TYPE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45725">
        <property type="entry name" value="FORMIN HOMOLOGY 2 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="148"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="183"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="183"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="206"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="222"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="237"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="251"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="266"/>
            <end position="278"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ81761.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="421" mass="48690" checksum="26691A7C204016DF" modified="2016-11-30" version="1">MDRATEAAASDLAEVRKLIEGMSALVNSQQEQQQQRQLEFAKQRQLLEQQQQKQLQQQQLLQQTQLLRKQQEQAQLEAQRQQAQREAQARLLKQQAQEQAQEQAQKEAQARLQKQQEEQARLQKQQEEQARLQQEEQARLQQQQQREEQARLQQQREEQARLQQEEQARLAQQQQQQQHQQNQEQQQQQQQNQEQQQQQQQQQLQPSQLHPQQAPSNHIGHSPQLQQQPQPSWSPQKTHTPSSPANISPSTPNTAVAPATANTGHHPPHHPHHPHHPHQAANTHTPQMAQPLPATGVIIEVNHLTFNRTLYFQLSPDATIEPLVAWLKLSFQDSTISGMVLQYKGFDGLWKCLLNRDDSLKRVLKQSLKNNTMLQMRVPREQDLLSSGYTDKRLLALTTKLTTPNLNVIMPPMPPPPTEDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MYC4</accession>
    <name>A0A1C7MYC4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_10536</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001223">
        <property type="protein sequence ID" value="OBZ81416.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MYC4"/>
    <dbReference type="STRING" id="101091.A0A1C7MYC4"/>
    <dbReference type="InParanoid" id="A0A1C7MYC4"/>
    <dbReference type="OrthoDB" id="10254377at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="38"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="133"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ81416.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="133" mass="15639" checksum="BE3D4C8685D90395" modified="2016-11-30" version="1" fragment="single">PEFIPQHLNEPVRRYISDDDQDDDDVIILTEEDDEEWTGYPLENTSSHITSSEEEWTGYPMTSSQDEDEDEIWRGYPMPQDEEEEQHISSPTSPFTPREEITEEWKGYKKTLEDTHQSSLRLANDTSLFHSTQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MYH4</accession>
    <name>A0A1C7MYH4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Protein PEROXIN-4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">PEX4</name>
        <name evidence="3" type="ORF">A0J61_10493</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001200">
        <property type="protein sequence ID" value="OBZ81456.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MYH4"/>
    <dbReference type="FunCoup" id="A0A1C7MYH4">
        <property type="interactions" value="208"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7MYH4"/>
    <dbReference type="InParanoid" id="A0A1C7MYH4"/>
    <dbReference type="OrthoDB" id="9973183at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005777">
        <property type="term" value="C:peroxisome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004842">
        <property type="term" value="F:ubiquitin-protein transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051865">
        <property type="term" value="P:protein autoubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016562">
        <property type="term" value="P:protein import into peroxisome matrix, receptor recycling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006513">
        <property type="term" value="P:protein monoubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd23812">
        <property type="entry name" value="UBCc_ScPEX4-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.110.10">
        <property type="entry name" value="Ubiquitin Conjugating Enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050113">
        <property type="entry name" value="Ub_conjugating_enzyme"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000608">
        <property type="entry name" value="UBC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016135">
        <property type="entry name" value="UBQ-conjugating_enzyme/RWD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24067">
        <property type="entry name" value="UBIQUITIN-CONJUGATING ENZYME E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00179">
        <property type="entry name" value="UQ_con"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00212">
        <property type="entry name" value="UBCc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54495">
        <property type="entry name" value="UBC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50127">
        <property type="entry name" value="UBC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="UBC core" evidence="2">
        <location>
            <begin position="3"/>
            <end position="155"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ81456.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="157" mass="17670" checksum="DDAEE106CFA6AE56" modified="2016-11-30" version="1">MNAVSKRLLKELREIDKEAKAHPEIISLAPQTEDDLLKWKALLAGLPDTPYEGGLFELSIEIPSNYPIHPPHIKFVTTICHPNIHFKTGEICLDILKTAWSPAWTLKSTLLAISLLLSNPEPSSPLNCDAANLLRCNDQLGYESLIRMYTQLYAQHQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MYR5</accession>
    <name>A0A1C7MYR5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Bifunctional dethiobiotin synthetase/7,8-diamino-pelargonic acid aminotransferase, mitochondrial</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">BIO3-BIO1</name>
        <name evidence="3" type="ORF">A0J61_09998</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000997">
        <property type="protein sequence ID" value="OBZ81953.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MYR5"/>
    <dbReference type="STRING" id="101091.A0A1C7MYR5"/>
    <dbReference type="InParanoid" id="A0A1C7MYR5"/>
    <dbReference type="OrthoDB" id="425114at2759"/>
    <dbReference type="UniPathway" id="UPA00078"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004015">
        <property type="term" value="F:adenosylmethionine-8-amino-7-oxononanoate transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004141">
        <property type="term" value="F:dethiobiotin synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009102">
        <property type="term" value="P:biotin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd03109">
        <property type="entry name" value="DTBS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00336">
        <property type="entry name" value="BioD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004472">
        <property type="entry name" value="DTB_synth_BioD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42684">
        <property type="entry name" value="ADENOSYLMETHIONINE-8-AMINO-7-OXONONANOATE AMINOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42684:SF3">
        <property type="entry name" value="ADENOSYLMETHIONINE-8-AMINO-7-OXONONANOATE AMINOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13500">
        <property type="entry name" value="AAA_26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 3" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0808">Transferase</keyword>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="375"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ81953.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="375" mass="42077" checksum="16962BB51DFACDA3" modified="2016-11-30" version="1" fragment="single">MPSTFLPTRAFQAYQIFAANTNVGKTILATGLCRAAAIVAKENNRDVFYMKPVQTGYPVDSDERHVKTFNGSDLLKTSTLYAYPDPVSPHIATNKPPHDKEVLERVKEHMLDCVRRQKKNGSYLFLETAGGIHSPVMSGTPQVDFYRSLRLPTILVGDSNLGGISTTLTSLESLHIRGYDVPTILLFDQPKYKNHTLIHQQAQKMNGSLVATIPHPPALLEDPVLEKASMERYYAQVDEYLLPVIKALDIQHQERFDRLETMAEKSKETFWWPFTQHEIIKDVTVIDSAYQDHFTTYSKPDTPQEMFDSCASWWTQGLGHGNPDLTLAAAHAAGRYGHVIFPESTNESALSLAEKVLEKDSWASRVFFSDNGSTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MZL4</accession>
    <name>A0A1C7MZL4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_09651</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000900">
        <property type="protein sequence ID" value="OBZ82300.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MZL4"/>
    <dbReference type="InParanoid" id="A0A1C7MZL4"/>
    <dbReference type="OrthoDB" id="2280875at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="78"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="193"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="31"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ82300.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="215" mass="24699" checksum="C7289427448A898F" modified="2016-11-30" version="1">MYVPSTAPSQKHQAPPINNLSHQEENSTVNKKKEQAINAQEKQDNVISDKCKKQPKTEVKTHVNNHFFPSPTYSCVSTSNSLDDKPDSRLDLISPETTPNHSEDEEEEEGAEKKDNNWYSPFSTGLDLDILPKLNLMDPLCQYKIDFKYNINIPLQHHYYHSHHHSHPYFRSSLHSAQNVSCIKVLENHPFISSKDSHSTHHQHVFGPVGDRKKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N049</accession>
    <name>A0A1C7N049_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">CN hydrolase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">A0J61_09583</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000884">
        <property type="protein sequence ID" value="OBZ82368.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N049"/>
    <dbReference type="STRING" id="101091.A0A1C7N049"/>
    <dbReference type="InParanoid" id="A0A1C7N049"/>
    <dbReference type="OrthoDB" id="2626014at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016410">
        <property type="term" value="F:N-acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042158">
        <property type="term" value="P:lipoprotein biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.110.10">
        <property type="entry name" value="Carbon-nitrogen hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004563">
        <property type="entry name" value="Apolipo_AcylTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003010">
        <property type="entry name" value="C-N_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036526">
        <property type="entry name" value="C-N_Hydrolase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38686">
        <property type="entry name" value="APOLIPOPROTEIN N-ACYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38686:SF1">
        <property type="entry name" value="APOLIPOPROTEIN N-ACYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00795">
        <property type="entry name" value="CN_hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56317">
        <property type="entry name" value="Carbon-nitrogen hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50263">
        <property type="entry name" value="CN_HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="31"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="65"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="97"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="199"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="467"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="domain" description="CN hydrolase" evidence="9">
        <location>
            <begin position="230"/>
            <end position="460"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50263"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OBZ82368.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="502" mass="56514" checksum="E7193516DA0B81A0" modified="2016-11-30" version="1">MFKELTKVRDFLLNKTEHLGLGINQSQHSSCINIGVAYVVSSVGFSLGFLGTFKNASESGFFPGAWLVMLCSFLINLITPISLLAERYLLKQPHQRFVRVLFFPMLWTGLFQLFYRFSGLGDYFSWTTNATVWSDFGQIASLGGRPLIEFTVALFGACLLEVLPANKSVDEYRETEDITEFQGEIEEMPDRVVHPWKAFWLHPMTLCLVFLAILLSYGGIATNIQAKSFYQADYPNYVPRKQQVGCVIGSHNDKHRYNHAEWFDMTESLAESGSKLVLWSELTAHVYNKTEEDVLIKKAKKVAVKHQIYLGITYSVGNPTTVNKLVFITKNGDIGIDYNKAHPVPGAEPQAGGPNKLQYVDTEEFGRVGGAICFDYSFTSLIGQASKYKIDLMLQPSWDWGPIGTYHEQGNMLRNVENGFTRLRCASQSVSGVTEATLNSPFNQRVASLNNDKLTFYLPLRKRVRTFYGLIGDSFGYICLAIGLSFLLATFVQRRKEGRVSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N0H8</accession>
    <name>A0A1C7N0H8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Sphingolipid C4-hydroxylase sur2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">sur2_0</name>
        <name evidence="7" type="ORF">A0J61_09420</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000846">
        <property type="protein sequence ID" value="OBZ82531.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N0H8"/>
    <dbReference type="FunCoup" id="A0A1C7N0H8">
        <property type="interactions" value="102"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N0H8"/>
    <dbReference type="InParanoid" id="A0A1C7N0H8"/>
    <dbReference type="OrthoDB" id="408954at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008610">
        <property type="term" value="P:lipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006694">
        <property type="entry name" value="Fatty_acid_hydroxylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050307">
        <property type="entry name" value="Sterol_Desaturase_Related"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11863">
        <property type="entry name" value="STEROL DESATURASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04116">
        <property type="entry name" value="FA_hydroxylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="28"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="77"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="125"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="domain" description="Fatty acid hydroxylase" evidence="6">
        <location>
            <begin position="137"/>
            <end position="272"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF04116"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OBZ82531.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="292" mass="34070" checksum="975FD313E3BBE67C" modified="2016-11-30" version="1">MNTTLDNTSNYTSQGNVSLYDIWSDEMLAIWVPIAVYWIQSSLFEILMRLQIPFFEQYRMTTPNEKEKRNKVSFTKVLWMVAVQHIIQIAVGVALMKTQSSVKPSHSLFVQLLIQIQPSWIPTTISYHYIIPCIQFFCAMFIIDTHQYALHRLAHSNRFLYKHMHSHHHRLYAPYAFGALYNHPVEGFLLDSCGGALAFELTGMSPRLGMYFFIFSTLKTINDHCGYSFPWDPLTICFNNNVNYHHIHHQAYGIKANFSQPFFTFWDVLLGTEYTQVMKTKSSKISQKDKQI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N0N5</accession>
    <name>A0A1C7N0N5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Negative regulator of sexual conjugation and meiosis</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">ran1_3</name>
        <name evidence="2" type="ORF">A0J61_09244</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000807">
        <property type="protein sequence ID" value="OBZ82705.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N0N5"/>
    <dbReference type="STRING" id="101091.A0A1C7N0N5"/>
    <dbReference type="InParanoid" id="A0A1C7N0N5"/>
    <dbReference type="OrthoDB" id="541276at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="92"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="111"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ82705.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="147" mass="16811" checksum="D2021838DD5A68D9" modified="2016-11-30" version="1" fragment="single">NPWRLASLEDETFCGFLQDPNLLLKILPISIELNRILKRIFCLDPHRRITLDELHARISRCAHFTRTPEVIRYETMMLLNKKKKKTMKIQLPSTQLDLPSPPQTPGADNRSLCSTPSTQSALTEPDSTGLYDNQKKGNLDSQLRIVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N1P1</accession>
    <name>A0A1C7N1P1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_09054</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000763">
        <property type="protein sequence ID" value="OBZ82898.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N1P1"/>
    <dbReference type="InParanoid" id="A0A1C7N1P1"/>
    <dbReference type="OrthoDB" id="2285768at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="46"/>
            <end position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ82898.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="137" mass="15365" checksum="BE84D7C0ABF4F88C" modified="2016-11-30" version="1">MNTNTTRWWWKKSSNSSKSDPIPTTLNEPDEEGSVCSYGDSLTPYPVSSSMRAQRTRSEYSANFSTDVESTASIRSKPWVSKHVDHESLEDSQSIRSRPDSIASDNNVVVTQPLETKKGTLVDYIVNKPLQLKVRLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N276</accession>
    <name>A0A1C7N276_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">LysM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">A0J61_08734</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000701">
        <property type="protein sequence ID" value="OBZ83213.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N276"/>
    <dbReference type="STRING" id="101091.A0A1C7N276"/>
    <dbReference type="InParanoid" id="A0A1C7N276"/>
    <dbReference type="OrthoDB" id="5985073at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008061">
        <property type="term" value="F:chitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00118">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.350.10">
        <property type="entry name" value="LysM domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018392">
        <property type="entry name" value="LysM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052210">
        <property type="entry name" value="LysM1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036779">
        <property type="entry name" value="LysM_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34997">
        <property type="entry name" value="AM15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34997:SF1">
        <property type="entry name" value="PEPTIDOGLYCAN-BINDING LYSIN DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01476">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00257">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54106">
        <property type="entry name" value="LysM domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51782">
        <property type="entry name" value="LYSM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0147">Chitin-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0843">Virulence</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008889435" description="LysM domain-containing protein" evidence="4">
        <location>
            <begin position="20"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="domain" description="LysM" evidence="5">
        <location>
            <begin position="87"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="domain" description="LysM" evidence="5">
        <location>
            <begin position="147"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="204"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="207"/>
            <end position="305"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022669"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OBZ83213.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="496" mass="55785" checksum="2B2783202D702BA5" modified="2016-11-30" version="1">MHISIAIIAIAILPSTAIALTSMSSSKTTATYNNVETSPHAASYLAPFASNDAIEKPYELIDDHEDLIQKRDGTLVSLRKRGDDCEKYHKAVRGDDCYKLSLKYEIDMDNIYQWNSQINSKCTNIYPGKKYCIKKQNVSTLAKACVKTHIVSSYDNCISVAKSNGISVNQFYDMNPSIHRGSCDNLLTGGTYCVKESDSSRFVSNKVAKKKSSARRTPSKRKKTTKKKKSTKKKSTKKKSTKKKSTKKKSTKKKSTKKKSTKKKSTKKKITRKKTSSRKKTTTKKKTTTKKKTTTKKKTTTRKATKTSTGTTDQRKLLQKGSALTYYWIAHPDDYEHSGKQVTIKTCDGKSLGTVAQKYADALVMEGTGIVGDKIINLGGCTCRDYQCFMEVDKKEDPYGLTAYGGPLRPFITIAANDIKRDTKIFVPEIVGWEIPGTAKKHNGCLLVDDQSWSFDRNHIDLYVYREKHYRTLNSEHKVSKVDIYEGGDCHLLNYE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N320</accession>
    <name>A0A1C7N320_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Nitrogen regulatory protein areA GATA-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_08553</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000670">
        <property type="protein sequence ID" value="OBZ83398.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N320"/>
    <dbReference type="STRING" id="101091.A0A1C7N320"/>
    <dbReference type="InParanoid" id="A0A1C7N320"/>
    <dbReference type="OrthoDB" id="5563539at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005773">
        <property type="term" value="C:vacuole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042149">
        <property type="term" value="P:cellular response to glucose starvation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007039">
        <property type="term" value="P:protein catabolic process in the vacuole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013860">
        <property type="entry name" value="AreA_GATA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052292">
        <property type="entry name" value="Glucose_repression_reg"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28051">
        <property type="entry name" value="PROTEIN MTL1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28051:SF1">
        <property type="entry name" value="PROTEIN MTL1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08550">
        <property type="entry name" value="GATA_AreA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nitrogen regulatory protein areA GATA-like" evidence="2">
        <location>
            <begin position="39"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="126"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="269"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="468"/>
            <end position="531"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="130"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="145"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="288"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="299"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="367"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="484"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="504"/>
            <end position="515"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF08550"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ83398.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="552" mass="62570" checksum="B4C93BE07D5C289D" modified="2016-11-30" version="1">MFVKKHAQDDDFESPRNITTENNVDYLSYKFDEMDLAASWRMLTKQKMTIVNGIRLENASWRTWAKQRNNLKTVSPETLNWLKDSDVTWLYGPLHTVIKDMDEQDRYAKPKVTTTEDALGLMTALQQQPKESDEQQKQPKEQQKDSANQLSQPEEQVQQQEQQQKMEPAKEKDATVISSAVHPQRPTASPLQNGKPLKSALKKVTMSDILKRSVSELQIHNESSPTNLTSGISISEANQQLGAFSPSVIASHRQPKLRFNQYVEQCVALSSSSEDNSRKKTSRVRMASLNDETTTNEDTSTDDNDYDPDEDSDAGSLIVMRRPQKMRSSIKKIEPALLKTNSRSEDSINSDSSDDEIIPTSSNNAYRQRKSHRHHKSSHHHHHEDWDAESAESDAFLSHIIQVSKGKQPIVHHGSASSRIPANEVHWETNRFSNDDEEILQSKSDYDYVFDDDDWDTHSEHMDDFPKFSQSYSYDEDEGGHNLPNASNSSTHTTAHIEVSPNPKIERDTNNKVDTMRSGSNGGNNGNSSLFSNIANWASSHLWPSDDDSSKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N3A8</accession>
    <name>A0A1C7N3A8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_08344</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000633">
        <property type="protein sequence ID" value="OBZ83603.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N3A8"/>
    <dbReference type="STRING" id="101091.A0A1C7N3A8"/>
    <dbReference type="InParanoid" id="A0A1C7N3A8"/>
    <dbReference type="OrthoDB" id="1882547at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11350">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36050">
        <property type="entry name" value="O-FUCOSYLTRANSFERASE 30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36050:SF1">
        <property type="entry name" value="O-FUCOSYLTRANSFERASE 30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ83603.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="486" mass="55950" checksum="CE9314478FC8BCC9" modified="2016-11-30" version="1">MWIKNRKASVALLSILVASLVSTLYYLFVQQSSFNRKEKYLAYLPHSGLSNQRIELANALLLAAILKRTLIVPPAFLGSVVGWMPMEQLLDHLNWLTTPKDFESICQPPTPGQISSYLQRSKCAEYNQFAAIPWHQLHDFSQLEPYVKVKFRDTVSFDLLQRDLGIDDSDTFVHRDEHLYDWRLYEDIEEANRILNNGSNFIDSFTDRKFYKIFTPQHWQKRKETLLFLGGIFGSTRMNMAKPEHIELQRLIASALHYRLDTPLGETVANIVQHLGGKATFNAVHFRLRDIPFRKYATDNLHQFERNMSIATGIPVPPLPPFDEFGVLTSLPKPPPPPAHPIYIDPQHNLSLPPWSNLCENVSPDFSVSMEHVGSRAVVYIATDHKDIRGENSRLLEWFDYFPCTLTLNDIPSELMNPLDAMHCMFSPNKSLKSYLIPLVDAMVAAHARRIFTTPRSTFSKYIGELNEAWVLREQGYNLSSFYIYE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N3M0</accession>
    <name>A0A1C7N3M0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF7707 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_08312</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000628">
        <property type="protein sequence ID" value="OBZ83637.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N3M0"/>
    <dbReference type="InParanoid" id="A0A1C7N3M0"/>
    <dbReference type="OrthoDB" id="1708823at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056124">
        <property type="entry name" value="DUF7707"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24808">
        <property type="entry name" value="DUF7707"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF7707" evidence="2">
        <location>
            <begin position="42"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="147"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="155"/>
            <end position="165"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF24808"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ83637.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="212" mass="23293" checksum="41A571F9BCFDDCF1" modified="2016-11-30" version="1">MALFAIFHAAHTLEMSIAEEIPYSMYPKAKLDVLPEISWNVLHIDLVNRENLCTRQIAYCANSCGGPDEAPKNFCNATSMAWGCGCSKKKVSFTKHSWPVVQAECAGKAQECRSICTKDVKNLGNCVTACNNHYQCGTNKAPPSFLETNDPSDKPSYNGSGSGKNIPNREIGLDEYGIADFTGRASSVTIDLAHTLCFVMIIQVLHYLIWGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N432</accession>
    <name>A0A1C7N432_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_08057</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000587">
        <property type="protein sequence ID" value="OBZ83895.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N432"/>
    <dbReference type="STRING" id="101091.A0A1C7N432"/>
    <dbReference type="InParanoid" id="A0A1C7N432"/>
    <dbReference type="OrthoDB" id="5600582at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="261"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="290"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="50"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="82"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="130"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="140"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="166"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="178"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="198"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="231"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="303"/>
            <end position="322"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ83895.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="574" mass="61934" checksum="43910592DA7C11DF" modified="2016-11-30" version="1">MDRYSRGYDDRYRGYYDRPRSDTYRPAENYRTERDYRDSGRNYSPNPHYSSSRSPGPSSGSGTRGDRYGYSDTRPYSSHYNSRGPSPSRSSSRSPRRPSYGYYRGGTSYPAYSSRRSPSPTNGGRSGSSSRRDSYDHRSYYSQYPSSSYRGSSGDPYPPYSRRHYSSYSNHGYGPPSNSSGYRSNSREPSVGPPAIHQPLSSSSAQRSIQSTPTSTAPNSPRHASVFQRESSSVSAGNNNNGASLPPASISNSTSAAASSTQADTVLPSNSKSLSTTSTLPSARIASAHISTAAPPPPPPPFSSTTFNSKDYATASGSETVGPNTINTTNTNAPISASKAMVTPNAFVTASATTTTTTTTTTVNSNNIGIPATLSNMSANVTTSSGPIHVPLPPSHTASSGSSSIYLYASSSSAAYSNSGGPIHNAPTRHGGPPGHHHNSNYHYGSSYYNNNYHSSPATTMPPIRQRISWAPDQEKEVDRYHSDLKKLFEEENKILAASRKSRFELELAVWETNKMEHQLELVQKQWEENGMEELVREESRVFAMTAVSGNASAASIKQIASIGANFGAKLAIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N469</accession>
    <name>A0A1C7N469_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">60S ribosomal protein L30</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">RPL30_0</name>
        <name evidence="6" type="synonym">RPL30_1</name>
        <name evidence="6" type="ORF">A0J61_02622</name>
        <name evidence="5" type="ORF">A0J61_08128</name>
    </gene>
    <organism evidence="5 7">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 7" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the eukaryotic ribosomal protein eL30 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000599">
        <property type="protein sequence ID" value="OBZ83817.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="LUGH01000101">
        <property type="protein sequence ID" value="OBZ89332.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N469"/>
    <dbReference type="FunCoup" id="A0A1C7N469">
        <property type="interactions" value="515"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N469"/>
    <dbReference type="InParanoid" id="A0A1C7N469"/>
    <dbReference type="OrthoDB" id="1928736at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1330.30:FF:000001">
        <property type="entry name" value="60S ribosomal protein L30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039109">
        <property type="entry name" value="Ribosomal_eL30-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029064">
        <property type="entry name" value="Ribosomal_eL30-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022991">
        <property type="entry name" value="Ribosomal_eL30_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004038">
        <property type="entry name" value="Ribosomal_eL8/eL30/eS12/Gad45"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF002172">
        <property type="entry name" value="PRK01018.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11449">
        <property type="entry name" value="RIBOSOMAL PROTEIN L30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01248">
        <property type="entry name" value="Ribosomal_L7Ae"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55315">
        <property type="entry name" value="L30e-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00709">
        <property type="entry name" value="RIBOSOMAL_L30E_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00993">
        <property type="entry name" value="RIBOSOMAL_L30E_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 5" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Ribosomal protein eL8/eL30/eS12/Gadd45" evidence="4">
        <location>
            <begin position="13"/>
            <end position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OBZ83817.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OBZ89332.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="108" mass="11691" checksum="EF702765A588A834" modified="2016-11-30" version="1">MAPATKSKKNAESINSRLQLVTKSGKYTLGYKTTLKTIRQGKAKLVIIAGNCPPLRKSEIEYYAMLSKTGVHHYNGNNIDLGTACGKLFRTSVLSITDAGDSDILTAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N4A4</accession>
    <name>A0A1C7N4A4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_08024</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000583">
        <property type="protein sequence ID" value="OBZ83920.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N4A4"/>
    <dbReference type="InParanoid" id="A0A1C7N4A4"/>
    <dbReference type="OrthoDB" id="2255497at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ83920.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="263" mass="29629" checksum="07C445324EE89B23" modified="2016-11-30" version="1">MKIGESSPAQGIVCRKRSYNDARVGFKVDLRLLFDSRQNEHDLLVLEAAKAGDASKLCYDICNLMREAKDNLDAILQHILKRHMKKPVLSWYMHTNGVTAHTGTVHIAKARFYLALHESKIHFLRNLASLQAFKNEFVMLISMAFDLKRNALMIKKSMDLLDCRKDSVMSRHVDPDDCLDANSFLSSIRPTFYYPPRDQVSLAVLPVNLFGVATAATVSSVSSPPCHAGLEPDEYGWAAVDNGHFYHIHTGITAERHPFDDRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N4E0</accession>
    <name>A0A1C7N4E0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Transcription factor domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_07963</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000572">
        <property type="protein sequence ID" value="OBZ83992.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N4E0"/>
    <dbReference type="STRING" id="101091.A0A1C7N4E0"/>
    <dbReference type="InParanoid" id="A0A1C7N4E0"/>
    <dbReference type="OrthoDB" id="9970124at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050987">
        <property type="entry name" value="AtrR-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46910:SF1">
        <property type="entry name" value="MISCELLANEOUS ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46910">
        <property type="entry name" value="TRANSCRIPTION FACTOR PDR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ83992.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="786" mass="90809" checksum="33914DF83116E402" modified="2016-11-30" version="1">MFLFDSNEVIKQTKTKRGKNSKSIEAVEAKAAAKAKKIMQDDMDALQITFYEIESWIEKTTPVLNRMTRELEKASKHFSVNKKPRHTPPSPAKNDMSLLLERYQHYFTAMQWSLSFLPDNSVRLETNITSIEQLVEAVQKIQLIAEPMLSDNTMASNNNDTHTLNDDHDSMLTPSYQDMASETMSEDGSITSTVIIDPSIEYWSIAMFRRPPLLDEDLKDTELNLKGLTEDVTPSVLTYICQTYWDCLHPKFSEDWSTFWDRSGDPELNQICIDSGLAMVFAHIIRHHNGACANAHALSYYYYNRARNLLMEYFDSPSMATIEALLNLSFLLMLKKQDSHSRTYLELAYRMMHQLNIHSMSLLSKDRLVRKNSLKVYLVFYYTDVMLSLYSEQQSIVDDKADDIDFYEIISLNKALIEHGEVNYDDRTIAKETFFAHMLELIRLSKRIQTLAQDYQRQNLHHHHMGALPTRWMRRVQKLEIALATWFDRLPRMYRIDPKPTEVYLKTHTTKTHDHGMMDVKSLREQSALLLMLQYQTQWLTLHKTFLSSNISTSLLKTMDISDADRNTLPRSPTGTTPYSTYRSHAICSDAANRIVVLAEIITEKFNWCSCQQFLTCVYQASLVYCKRIMNKDDDYKTNKAMIQRIMRILAANKVNYEGLPDDLTDCLNDFLSENNKDDAYPACSATVNNDLLDQIFPTGSISHRVVIYNDKMFNSPHMHQQCLSQNITARSSPAPDHAFSPEALYSIKLQNPPVVPIAMDFEDETSQKNWRCKFSSFNIASSHVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N4X5</accession>
    <name>A0A1C7N4X5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Synaptic vesicular amine transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">SLC18A2</name>
        <name evidence="9" type="ORF">A0J61_07810</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. Vesicular transporter family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000550">
        <property type="protein sequence ID" value="OBZ84140.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N4X5"/>
    <dbReference type="FunCoup" id="A0A1C7N4X5">
        <property type="interactions" value="2"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N4X5"/>
    <dbReference type="InParanoid" id="A0A1C7N4X5"/>
    <dbReference type="OrthoDB" id="5086884at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd17325">
        <property type="entry name" value="MFS_MdtG_SLC18_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050930">
        <property type="entry name" value="MFS_Vesicular_Transporter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001958">
        <property type="entry name" value="Tet-R_TetA/multi-R_MdtG-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23506">
        <property type="entry name" value="GH10249P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23506:SF23">
        <property type="entry name" value="GH10249P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01035">
        <property type="entry name" value="TCRTETA"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="31"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="72"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="104"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="160"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="190"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="250"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="283"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="307"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="349"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="384"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="8">
        <location>
            <begin position="34"/>
            <end position="409"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OBZ84140.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="409" mass="44445" checksum="2DAB2FBF034905A2" modified="2016-11-30" version="1">MHSADINCTHLESLDETTKPLSWYARAQRSAWSVAMLVALILFTDMLAYGAIIPCLPTLIIEKLHGTPKDIGILFGCFAFGYLISTPLFAVYSDTYKNRRYPIMLGSVCLIGSTLCFAWATCFSMFVIARLFQGVSAGASWTIGLGMLADTFPTETLGRVMGTVIIAHTVGFVLGPVIGGILYEAGGIRAPFYFCGLFGLFTLTTAFWIAESDKGQLEEHVPLITNGNKRVVLAGIEPALPIYLLKKYNASTATIGTIFVALVVPCFLGPLTGYLSDKYGRPYFIVAGMVLASFSAFLLSLPWEGSMYSVVPLLFLYGLSNPVVHTPLMPEMGYIVSQMNSTAYAQVYALYNMAYSLGTLIGPLVAGCIMSSSSLGDVSHQFHILMLLFSALILLFFPVSLVIAVKKFQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N514</accession>
    <name>A0A1C7N514_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Surfeit locus protein 4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">A0J61_07830</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SURF4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000553">
        <property type="protein sequence ID" value="OBZ84117.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N514"/>
    <dbReference type="FunCoup" id="A0A1C7N514">
        <property type="interactions" value="380"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N514"/>
    <dbReference type="InParanoid" id="A0A1C7N514"/>
    <dbReference type="OrthoDB" id="7859621at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002995">
        <property type="entry name" value="Surf4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02077">
        <property type="entry name" value="SURF4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="69"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="97"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="122"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="161"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="185"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="212"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="249"/>
            <end position="268"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006945"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OBZ84117.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="275" mass="31218" checksum="D968E26FA0FE6179" modified="2016-11-30" version="1">MSNVKEQMEAFSTKAEDFLDRAGQPMKPYIPVMSRFLIIATFLEDSLRIVTQWSDQINFMENTRHFPRGISHIFLGLNVLTMLIASFCIVAKKHQAYATYGLMGVIVAQAFGYGLIFDMSFFLRNLSVMGGLIMVLSETMVKRKQMFAALPQISETNRRMYLQLAGRILLIFLFVGSAFHGDWSVLRITVSLLGLAACIMVAVGFKAKWSAMFLVLFLSVLNVFVNNFWSVQHSYYKRDFLRYDFFQSLSTVGGFLLLASTGPGGLSYDEKKKEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N538</accession>
    <name>A0A1C7N538_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">CTD nuclear envelope phosphatase 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">cnep-1_1</name>
        <name evidence="2" type="ORF">A0J61_07709</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000537">
        <property type="protein sequence ID" value="OBZ84243.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N538"/>
    <dbReference type="STRING" id="101091.A0A1C7N538"/>
    <dbReference type="InParanoid" id="A0A1C7N538"/>
    <dbReference type="OrthoDB" id="277011at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016791">
        <property type="term" value="F:phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07521">
        <property type="entry name" value="HAD_FCP1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1000:FF:000093">
        <property type="entry name" value="NLI interacting factor-like phosphatase family protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011948">
        <property type="entry name" value="Dullard_phosphatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004274">
        <property type="entry name" value="FCP1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050365">
        <property type="entry name" value="TIM50"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02251">
        <property type="entry name" value="HIF-SF_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12210">
        <property type="entry name" value="DULLARD PROTEIN PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03031">
        <property type="entry name" value="NIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00577">
        <property type="entry name" value="CPDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50969">
        <property type="entry name" value="FCP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FCP1 homology" evidence="1">
        <location>
            <begin position="68"/>
            <end position="235"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50969"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ84243.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="252" mass="29384" checksum="1660DA11C96DECC9" modified="2016-11-30" version="1">MSATLTTSYSTNITATNNKTRLGKKRTKQFFHFIYHYLCIIYRFFHDLLFIPHTTIQKKKTIPSQASNYYKNKTLILDLDETLVHSVRLGSEASFTQVSPSVIHKSIEVQSDKQRLFYEVYKRPHVDFFLKTISQWYRVVIYTASMAEYADPVIDWLDQEHMISQRLFRQSCVLRNGNYLKDVTLAEEDLCKVCLVDNSPVAFDLYKDNGIALPTWISNPNDESLLDLLPFLDALRFAADVRSILKLQHKQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N5A1</accession>
    <name>A0A1C7N5A1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">A0J61_07767</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1 8">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000544">
        <property type="protein sequence ID" value="OBZ84187.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N5A1"/>
    <dbReference type="InParanoid" id="A0A1C7N5A1"/>
    <dbReference type="OrthoDB" id="1470350at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050196">
        <property type="entry name" value="Cytochrome_P450_Monoox"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24291:SF50">
        <property type="entry name" value="BIFUNCTIONAL ALBAFLAVENONE MONOOXYGENASE_TERPENE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24291">
        <property type="entry name" value="CYTOCHROME P450 FAMILY 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 7 8" id="KW-0349">Heme</keyword>
    <keyword evidence="5 7 8" id="KW-0408">Iron</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 7 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 8" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="4 8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="7">
        <location>
            <position position="465"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <feature type="non-terminal residue" evidence="10">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OBZ84187.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="521" mass="59429" checksum="1B89CB4106433C23" modified="2016-11-30" version="1" fragment="single">YQTHILPRLTRRSQTLGISAAITLVLAYVVNDRLLRPPKHFRHLPCLGYVDVLKSILTGESSLDLVKRKVIPMLESEDYPGAYLKLERTGWEVYVTHPQDAKYVVLKPDLFPKFTPGFAEDDTCLRKFLDGNSLIVLNGSRWRAQRKVANPAFHRAMPVKLFGELTSELFEVIEKDGKSVVDVSDLMDRWTLQALGKAGFGFDFKAISEKENEWVKTYNTVDEAIQNPFFFLFPPLDRGSSRFLCPSRRECHREVEKLVGMMDQIVAKKREQIASGNSKNDDLVENEKDLLTLMIESEARGEGLMSDRELRSNLAAFFLAGHDTTAQSLAYTLYYLATHPEIQDKARDEAVRILGDEPKDVLPNLDQTKEFTYINQVIKESLRINPSVIRISLRVAAQDTAISSTLVPKGTRIRVDTYAIHHNKKIWTNPEKFDPERFSEEGEXHLREFRDGLSWLPFGSGARQCIGMLFSLNEQRVLLPMLLRKYTFSLPKDSIHKDGPISAGVLVLGPVDLEIEFKKRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N652</accession>
    <name>A0A1C7N652_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Nucleoporin Nup188 N-terminal subdomain III domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">A0J61_07361</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nuclear pore complex</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000492">
        <property type="protein sequence ID" value="OBZ84590.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="FunCoup" id="A0A1C7N652">
        <property type="interactions" value="66"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N652"/>
    <dbReference type="InParanoid" id="A0A1C7N652"/>
    <dbReference type="OrthoDB" id="102511at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044611">
        <property type="term" value="C:nuclear pore inner ring"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017056">
        <property type="term" value="F:structural constituent of nuclear pore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051028">
        <property type="term" value="P:mRNA transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006606">
        <property type="term" value="P:protein import into nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006405">
        <property type="term" value="P:RNA export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044840">
        <property type="entry name" value="Nup188"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048883">
        <property type="entry name" value="Nup188_N-subdom_III"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31431:SF1">
        <property type="entry name" value="NUCLEOPORIN NUP188"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31431">
        <property type="entry name" value="NUCLEOPORIN NUP188 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21093">
        <property type="entry name" value="Nup188_N-subdom_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0509">mRNA transport</keyword>
    <keyword evidence="6" id="KW-0906">Nuclear pore complex</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="4" id="KW-0653">Protein transport</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0811">Translocation</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Nucleoporin Nup188 N-terminal subdomain III" evidence="8">
        <location>
            <begin position="187"/>
            <end position="646"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004567"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022816"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023132"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF21093"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OBZ84590.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="1614" mass="179913" checksum="FB32A21C130E6056" modified="2016-11-30" version="1" fragment="single">NILESSICSEEDVNSCGYRGVIRVLLNSFLSITRPNYIPMESYTSLINAYCLVYKNQPELCRLFWETDFDKRNPASLLTTACGRFPVFFDDFVQLLSAVSGASDNETEQSDPLSAVEVFNYLCTIPSITVVLSPASRVAAKEEDGEAVVYAEQSLQVTPEMDFMHGIVIPEGTRGLLLSTSETERIVRFSTAYSGWHLIASILGTFASGNANRFIQVEDESQTLQGRNAAAIKSMLELIHNVLSSNPKLIPSLVNHLESITGGAVDGTDAPLLVSIICNIVTFCSTMEPCPIDILTLSVQCLTLLLPNYKSHIWQYLKYTPILPIMNSSVQLSSGITRPYSGSQIQQIVSKVEFTSGRYTLLLAFLDLIQGLVQDIQRSWWATENIQDVNQQCQVEVLYVCLHYLMLDVFPSYASWRYKKLSERFLIGTKLLSIFSEVAIHFKFPSANNTKLSLNSIREGIFSNFLYDGGIYHISPLIDTITEGARKANALYKSSYPKEAQRVEKLTEMTFCFVKILLQHRLEQIDQGNTVPESTLERLLLEQSTGTRSTDFLLRVARHIHYRHNITLPTEATNVLTLLCRTTAGWKIVPNFVQYLGSTEQVHSIIRTYLEIAKDHFQNENLSASIWQLMTTLMETQPSLAILFLDCGDFIMPSPKSAVRLLNGQVQSTSSAPSPVVTESAIRAATDLLSHWETLSVEKPTVTSNVLRFLATFWQTAFDHYALVERSRADSALWDVVGRVLLNPNNTMDTLNLDTLDLLDSKSKSIHFDQDVRRRCCLNLSKTHAMRIIAYEIHITAGNASGQTIAEKLPVGLKNLLSKLSDPAKLAAMREAFVKSDFDPNLVRQAESSADAVLETLGIQDRSILLCKMPRLGYGDDVACGEAHRYGDSYLYDYYLASTRIQSLYAEIANKYESVEKIDSMLLDPVEAVTSLKEYASQCLRSLLLVNHNSSIVDSQVTLIRSFKTFIEVCSRRSSDLIWSSRTNTGSTDTLHSFLKELIHAAQAETRDDGVTLTSYSVLVQFIRNLTEDWIDKNRSIVVGVDSHAKKAYAAKAFDLLSAISGLLNRENYALFQSICDITAIRFHRPLLESILLSLRTLRGMSEYLLDPLNPACTQLQTCLADILAVVCSSFHVLTIKASSYSAEGAQVAESVQESCIKDVTVVVSLLIELISSKYKIPEAVWLNVFAKHQTFSNVLNLFKAGIALVVDEVDRQCANVSSVYSISITPYAETALYFLLALSNIPKAAEQLVKENLFGALCSNALTPRLQCGTLDLFIRFGDGNNPAFVERNPLHSNWCQMLGVINNLMRTLGRSELVLPNVVSFMQIYSPQIGTAYTNANGANDPIFGLNPSESLSSPLLEEIQRISMVFFGLSKQLDKLSRLADNLFVSFKDCSLFLLQRYHYFLTHPAHMQAQLYPVDNIERQQAQTFDSTPQDDSKLRTPSALMKSITKSILTITHYTLSTLAILTQAPLILTTDDVEWPFGNAIMNPDSRVILGEAASFGTLIEYINVCLGMMSQGQDNKGVPTQELLNVIQDCALLVTTQLSLWIAKPNITNSTRFDIAQQNVTDVAEILNKASASLMKLEGSQKTGHVKLQLGLIRSLQCFLSNRFFEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N663</accession>
    <name>A0A1C7N663_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Ubiquitin carboxyl-terminal hydrolase</fullName>
            <ecNumber evidence="14">3.4.19.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="primary">ubp14</name>
        <name evidence="18" type="ORF">A0J61_09113</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18 19">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).</text>
            <dbReference type="EC" id="3.4.19.12"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 14">Belongs to the peptidase C19 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.19.12" evidence="14"/>
    <dbReference type="EMBL" id="LUGH01000777">
        <property type="protein sequence ID" value="OBZ82834.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N663"/>
    <dbReference type="FunCoup" id="A0A1C7N663">
        <property type="interactions" value="775"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N663"/>
    <dbReference type="InParanoid" id="A0A1C7N663"/>
    <dbReference type="OrthoDB" id="361536at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004843">
        <property type="term" value="F:cysteine-type deubiquitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016579">
        <property type="term" value="P:protein deubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02658">
        <property type="entry name" value="Peptidase_C19B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd14386">
        <property type="entry name" value="UBA2_UBP5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.10:FF:000086">
        <property type="entry name" value="Ubiquitin carboxyl-terminal hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.40.10:FF:000396">
        <property type="entry name" value="Ubiquitin carboxyl-terminal hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.40.10:FF:000587">
        <property type="entry name" value="Ubiquitin carboxyl-terminal hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.70.10">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.10">
        <property type="entry name" value="DNA helicase RuvA subunit, C-terminal domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050164">
        <property type="entry name" value="Peptidase_C19"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001394">
        <property type="entry name" value="Peptidase_C19_UCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015940">
        <property type="entry name" value="UBA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009060">
        <property type="entry name" value="UBA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016652">
        <property type="entry name" value="Ubiquitinyl_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041432">
        <property type="entry name" value="UBP13_Znf-UBP_var"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028889">
        <property type="entry name" value="USP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018200">
        <property type="entry name" value="USP_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001607">
        <property type="entry name" value="Znf_UBP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24006">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24006:SF664">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00627">
        <property type="entry name" value="UBA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00443">
        <property type="entry name" value="UCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02148">
        <property type="entry name" value="zf-UBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17807">
        <property type="entry name" value="zf-UBP_var"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016308">
        <property type="entry name" value="UBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00165">
        <property type="entry name" value="UBA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00290">
        <property type="entry name" value="ZnF_UBP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46934">
        <property type="entry name" value="UBA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50030">
        <property type="entry name" value="UBA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00972">
        <property type="entry name" value="USP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00973">
        <property type="entry name" value="USP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50235">
        <property type="entry name" value="USP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50271">
        <property type="entry name" value="ZF_UBP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 14 18" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 12" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 14" id="KW-0645">Protease</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="9 14" id="KW-0788">Thiol protease</keyword>
    <keyword evidence="7 14" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="10 12" id="KW-0862">Zinc</keyword>
    <keyword evidence="6 13" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="UBP-type" evidence="17">
        <location>
            <begin position="1"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="domain" description="UBP-type" evidence="17">
        <location>
            <begin position="167"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="domain" description="USP" evidence="16">
        <location>
            <begin position="318"/>
            <end position="771"/>
        </location>
    </feature>
    <feature type="domain" description="UBA" evidence="15">
        <location>
            <begin position="589"/>
            <end position="630"/>
        </location>
    </feature>
    <feature type="domain" description="UBA" evidence="15">
        <location>
            <begin position="651"/>
            <end position="691"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="11">
        <location>
            <position position="327"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="11">
        <location>
            <position position="733"/>
        </location>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="191"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="194"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="211"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="224"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR016308-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR016308-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU366025"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50030"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS50271"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="OBZ82834.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="771" mass="86496" checksum="FCEA73F7EF63D244" modified="2016-11-30" version="1">MVCSHIESSSLQPPSVYTQVHKEECTQCFDSQDSPEGIDVCLTCFNGGCLDTDRHHALTHHQLTGHPLALNIRRTIVEQSSNTKRTDDDTPPPPKMTKLAISEEDQTPVYDYHTQVRCYACQKLEPKETWSPKLIRPIQLNAAVEAVMNAMSSAKQSEVKAWEEVITPCEHTLCLTQEAPKKLESQDLAHCADCELNQNLWLCLVCGNLGCGRKQYDGSGGNNHAIEHFEKTGHGVNVKLGTITAEGTADIYCYSCDDARIDENLATHLANWGINVAQQVKTEKNMTELQLEQNMKFDFSMTTEDGKQLAPRFGPGYTGLKNLGNSCYMASVLQSVFNIPAFQQRYGPQLDDHALTCTQADPANCWLCQLHKLADGLLSGRYAQPNQDESHQEGVAPGMFKALVGKGHAEFSTMRQQDAFEFFQYLCKSIQQKEHANTPLKPTDEFEFMLEQRLQCDQCKRVRYQTDQTSSISVSVPTQLLPDGEYAPVQFTELMDAFVQPETVEGYQCAHCQTKTTAYRSVKFKTFPNVLVINPRRFAFVNWVPQKLNIPLVFPQDNTPVNLDKYRGTGLQPGEEELPQEQTATEQPAFNQNDIDQLQAMGFSENRCKRALLNTGHQGAEVAMSWMFEHMEDPDIDDPLPDTTANATANAATEEQINTLQEMGFTASQAKKALRETDNNTERALDWLFSHPDDDGQDTTSAVEKSIGDNSPPFNYQLDSFVSHKGTSVHCGHYVAHVFKEGEWVLYNDNRVAVTPNPPIGEAYLYFLKRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N6A6</accession>
    <name>A0A1C7N6A6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Glutamate pyruvate transaminase</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Glutamic--alanine transaminase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">Glutamic--pyruvic transaminase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="primary">gpt</name>
        <name evidence="11" type="ORF">A0J61_07391</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="2">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. Alanine aminotransferase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000496">
        <property type="protein sequence ID" value="OBZ84558.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="FunCoup" id="A0A1C7N6A6">
        <property type="interactions" value="222"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N6A6"/>
    <dbReference type="InParanoid" id="A0A1C7N6A6"/>
    <dbReference type="OrthoDB" id="1732682at2759"/>
    <dbReference type="UniPathway" id="UPA00528">
        <property type="reaction ID" value="UER00586"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008483">
        <property type="term" value="F:transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042853">
        <property type="term" value="P:L-alanine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd00609">
        <property type="entry name" value="AAT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.1970:FF:000001">
        <property type="entry name" value="Alanine aminotransferase 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.640.10:FF:000012">
        <property type="entry name" value="alanine aminotransferase 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.1150.10:FF:000010">
        <property type="entry name" value="Alanine aminotransferase 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.1970">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045088">
        <property type="entry name" value="ALAT1/2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004839">
        <property type="entry name" value="Aminotransferase_I/II_large"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11751">
        <property type="entry name" value="ALANINE AMINOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11751:SF29">
        <property type="entry name" value="ALANINE TRANSAMINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00155">
        <property type="entry name" value="Aminotran_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 11" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="5" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 11" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotransferase class I/classII large" evidence="10">
        <location>
            <begin position="118"/>
            <end position="487"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00025785"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00077894"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00078532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00080525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="OBZ84558.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="512" mass="57576" checksum="65D2C2EB5498C188" modified="2016-11-30" version="1">MIRTLLRTTKNTNCIQLNHRATRFASTQAKKVLTVETMHPLVRNAEYAVRGALPIRAEALSQQLKKDPSKLNFERVVFCNIGNPQQLNQKPITFFRQVASLCENPELLKAENRELVSKLYPADAIAXAELLLKHIGSIGAYSHSKGIAHIRENVAKFIERRDGYSANPDHIFLTQGASEGVQKVIQLLTQNNTSGVMIPIPQYPLYSATLALVDAAPVPYYLNETQDWGLNVEDLKSSVEKARKDGVDVRALVIINPGNPTGQCLSEDNIREIIKFCHEERIILLADEVYQTNIYQPERRPFHSFKKVLMSMGSEYSNQELFSFHSTSKGMIGECGRRGGYFECVNIDPEILEQVYKISSISLCPNVHGQIMVDLMTNPPVEGDESYPQYKEEVDAIFESLRRRATKLAKCFNRLEGVTCNEAEGAMYLFPRIRLPTKAIEAANKAGVAPDAFYALGMLDATGVCVIPGSGFGQEEGTFHFRSTFLPEEHLFDKFCGSLEKFHQDFLNKYRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N7D4</accession>
    <name>A0A1C7N7D4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_07416</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000499">
        <property type="protein sequence ID" value="OBZ84536.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N7D4"/>
    <dbReference type="InParanoid" id="A0A1C7N7D4"/>
    <dbReference type="OrthoDB" id="2272101at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="119"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="212"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="246"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="224"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="267"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="284"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="297"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="338"/>
            <end position="348"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ84536.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="515" mass="59421" checksum="DD3633B81D4E5BA6" modified="2016-11-30" version="1">MPTLIKTKKKKKRILPQKEVLDLEFVSAPSSRHLTDNDLLFNGPSEHDRHILSELWGSADLNMRRPQVNIGKPQQMVPKDPPAVKPQLKEHLRKSDATWPMDLSHVSLLPSHLQQYHLKRRKQPDVSSENDKQESVNRMQKVRIYIKLKDFSDVHSPPQQDSESENEHIRLVDISEHIGSANLSESIHAQSKEESRVEDXPMVHAEPQDEIKQSQEERGLQLESIQSISTDSQDIPSEIMQLKDMPSESVQGLNTEPHVIQPEEETNTQSECTPMTNIEPQDVQPKEGNARSEKTQPETMQSESIQMDNAESGDVQPKEEDTQSEDMTTDSIQMINEEMQDVQSEDAPSESIQSEDIPQPEEEDLSIDCLSQAVQSKEDTQSKESTQPNHAHSEDRQPTKDTTFSRNAYRKKNSAPENTTKDRETNIPHKTQQAEIYNKTQLIKPVLSTFVDDQTKRDRTHIFLRQRQAHIWIINQPKTRHQNCTKRKERLLRKIRQPYIVQKKIKAVHWQVNDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N7Q7</accession>
    <name>A0A1C7N7Q7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_06940</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000443">
        <property type="protein sequence ID" value="OBZ85008.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N7Q7"/>
    <dbReference type="STRING" id="101091.A0A1C7N7Q7"/>
    <dbReference type="InParanoid" id="A0A1C7N7Q7"/>
    <dbReference type="OrthoDB" id="2262137at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="272"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="393"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="567"/>
            <end position="602"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="275"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="287"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="435"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="590"/>
            <end position="602"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ85008.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="602" mass="67722" checksum="DF738E4DA27E25AB" modified="2016-11-30" version="1">MDLLQRQQVVGDPMYLKACEMACKLLDASESLSVAVNQLQQAIENTTPEDSVHAPLRKAIDQYEHLLMINNVLKAIYPSVQNVRHQQYLESATVSATNTSNHQLSKVYQLVSNSRLNNDDRVQQELIYISRQIQSIVEQESVKQEVMDYTYTQANEALRSTASPVQRNTPPIQMQVTSPIQRLQSAPLFPSLQTQPPVSVSQQGQSMITPQASVIMSPQQTTQPVVIHSNLMQPTTAESSRQHIMSATTSVQPIVTVVSPQMEKSAMLPSCAASYPNSETSQQTQHSPDEFKREQTEPHQHYQQTEGNSSQTVQTQQSESFLASRFLEQFEATATEFAELNKIHVNSVWESMIVHALPSSQSEWAHEHLLGKDYTWEKAKQIFKKHFLESSRLSPPMTPADPNATLMKSRQRQAKPEQLSQQGTALQKVKHEKQYQQASGPTNGASANSVTYNRTAVYAEHLFSLEMKLYENIDAYNTRYLRYCNIANMDLCDVSLMQRYAKSLLKDYRKLIHTNISGKAIQTLPKLMELTSAIIKDYEGKHNTKKTVAPYSCPNDHSTLSSISFLSQKNQGNNKGPGPSNSRKRPTSFAEANTASKRPTIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N856</accession>
    <name>A0A1C7N856_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Forkhead box protein I1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">Foxi1</name>
        <name evidence="9" type="ORF">A0J61_08428</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000647">
        <property type="protein sequence ID" value="OBZ83524.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N856"/>
    <dbReference type="STRING" id="101091.A0A1C7N856"/>
    <dbReference type="InParanoid" id="A0A1C7N856"/>
    <dbReference type="OrthoDB" id="5954824at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00059">
        <property type="entry name" value="FH_FOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001766">
        <property type="entry name" value="Fork_head_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018122">
        <property type="entry name" value="TF_fork_head_CS_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45881">
        <property type="entry name" value="CHECKPOINT SUPPRESSOR 1-LIKE, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45881:SF1">
        <property type="entry name" value="FORK HEAD PROTEIN HOMOLOG 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00250">
        <property type="entry name" value="Forkhead"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00053">
        <property type="entry name" value="FORKHEAD"/>
    </dbReference>
    <dbReference type="SMART" id="SM00339">
        <property type="entry name" value="FH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00657">
        <property type="entry name" value="FORK_HEAD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50039">
        <property type="entry name" value="FORK_HEAD_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5 6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Fork-head" evidence="8">
        <location>
            <begin position="127"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="Fork-head" evidence="6">
        <location>
            <begin position="127"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="103"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="240"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="335"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="104"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="120"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="335"/>
            <end position="355"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50039"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OBZ83524.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="406" mass="47206" checksum="8C3B93C6F53364E5" modified="2016-11-30" version="1">MSSIIHLPGMRFIRDGQIEELDDSQLKDKAALLSQQQSQQWKQDDKLGFYQNTSDYYESLLRNRSYLEPNAGALPPSNHHQHHHHYDFSPQQVYPSYFATATAQQQQLEQQQQQMDLQKRPIRKRRRPPHSYASLIAQAILTSRDQRLTLREIYEWVQTRYPHLYEANETGWQNTIRHNLSLNRCFRKLPRLSQDNTGKGKGSKGGYWAVDLEQLNNTNFGRQILDSGFLGNIEYWHQQQQQQQQQQQQQQLPSPAQQQPQQIQRHPASQPHQQAQRQQSQQDIVDEIDFNTLVAPFYSSAGTIPTQQDDHRYTTEVDENVRMASFLARFNNKRSMSSLGSMTSSKTSSVRGSTSPHSPATTDMETPILSSAQLQQQYHQKLEMDPLLNPSLMRVVPRKFNVPFHQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N8A4</accession>
    <name>A0A1C7N8A4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Monocarboxylate transporter 12</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">slc16a12_0</name>
        <name evidence="5" type="ORF">A0J61_06595</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000405">
        <property type="protein sequence ID" value="OBZ85360.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N8A4"/>
    <dbReference type="STRING" id="101091.A0A1C7N8A4"/>
    <dbReference type="InParanoid" id="A0A1C7N8A4"/>
    <dbReference type="OrthoDB" id="6499973at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd17352">
        <property type="entry name" value="MFS_MCT_SLC16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050327">
        <property type="entry name" value="Proton-linked_MCT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11360:SF284">
        <property type="entry name" value="EG:103B4.3 PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11360">
        <property type="entry name" value="MONOCARBOXYLATE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="49"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="89"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="118"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="143"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="176"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="207"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="259"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="294"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="320"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="347"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="384"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="412"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="4">
        <location>
            <begin position="48"/>
            <end position="439"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OBZ85360.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="447" mass="48963" checksum="99C8ED01F0F411E4" modified="2016-11-30" version="1">MDEKTDDLSLSHHDKEILKDQQSTSTVINEDLEKSSSTFQGPPDGGWEAWLVVFGGFLGNVSIFGVNYTWAVFLSHYNTNVYPGKMNELSWIGSICVALFFVIGPINEWISCKIGYRYMLLIGAILCPLGLMLASITQEIWQLYLTQGVIFGLGASFVFFPSLAAPQQWFSSRRGLAVAGSMCGSGIGSLIFSNVAQAAIANLDYRWALRIEGFMCFALLLLAAAVVRPPKNAEPTQRESYAQLYQKQKQLMKSRSFQIMFLMGIVTTFGYLTPAFFLASYAEYLGLNPWVGSNLGAITSAVNTISMLVIGWISDRTGRFNGLFICTFLAGVFTLTLWTTATSEVSIWIYVVLYGFFGGGYLSLNGAALPEVAGYDNISAANGLFYITSTLGYMFGTPISSAIINSRSDPPGYIYAAVWSGVLMAVGGILCWMLRVTRSGWNPLIKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N9C3</accession>
    <name>A0A1C7N9C3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_06218</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000365">
        <property type="protein sequence ID" value="OBZ85732.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N9C3"/>
    <dbReference type="InParanoid" id="A0A1C7N9C3"/>
    <dbReference type="OrthoDB" id="2431558at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ85732.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="185" mass="21022" checksum="A29EEC2218CE1F7C" modified="2016-11-30" version="1" fragment="single">LQAAEGAEEQDNVVLEVCAEILSCLARKAKRWSKTNLGETTFIHDQLTDILDCTFGSLNADLFHYEIQDKWMSKASLKPDYLLSMNTCQSKPLDLYVMEAKTPEAHKGDMDFVKMSIMLKHMLDKIVLHGCHVFQYTMTLLFNGIYLMKEVSIGSLPSSPQEIDCLVPRYLKIMDITLLIVLNTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N9E8</accession>
    <name>A0A1C7N9E8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Centromere protein I</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">CENPI</name>
        <name evidence="8" type="ORF">A0J61_06231</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Chromosome</location>
            <location evidence="2">Centromere</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the CENP-I/CTF3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000367">
        <property type="protein sequence ID" value="OBZ85717.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N9E8"/>
    <dbReference type="FunCoup" id="A0A1C7N9E8">
        <property type="interactions" value="3"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N9E8"/>
    <dbReference type="InParanoid" id="A0A1C7N9E8"/>
    <dbReference type="OrthoDB" id="6347512at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000939">
        <property type="term" value="C:inner kinetochore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034080">
        <property type="term" value="P:CENP-A containing chromatin assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000070">
        <property type="term" value="P:mitotic sister chromatid segregation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012485">
        <property type="entry name" value="CENP-I"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48208">
        <property type="entry name" value="CENTROMERE PROTEIN I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48208:SF2">
        <property type="entry name" value="CENTROMERE PROTEIN I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07778">
        <property type="entry name" value="CENP-I"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0137">Centromere</keyword>
    <keyword evidence="4" id="KW-0158">Chromosome</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="27"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="97"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="120"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="142"/>
            <end position="153"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004584"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005470"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OBZ85717.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="871" mass="101327" checksum="334209E0697BC2C5" modified="2016-11-30" version="1">MEGNTRQHYSAIDSSSDNSDYEEEDKEDRVEEAIREDSENGIQSDHMEVDQQPESLSDQEVDQLRSESSSVRETISDEEAEQKEAGQQNRESHDTEQQDEVQQDIEQQDEEQQDEVQQDIEQHDTEQHDTEQHDAERHEKDEDQQDTEQQDEEATPKITLENATTRNVDKLIKPVVSICTMDISKKRSAKRAKKLLSICPLVQKFGLDQVEFNALFELIMSGLHNFSSCKSLIELLLPRDDIADDYVIRIIGSVSRKEAPLDIINLMLKWTVTVFDVINTKRRLSNLYHVFFRHLKYEELRHALCHVLYYLTKKEHVTTYRVTRLKEMIDSEKDNASLIALLMSYQTFDPTIVVPHNARLADMLVFTNPLPAVRENLIQLRLLWKHDLEPKLGSFKDEIRIPSAKRVRLTKRQNGPRIRVDPSTESRLIDVSQVINNMETVSLPEQLTMVLENRSLQYSLLYEASGTAVTRLSYYIVQMLYDLIASGNKKDPQKTEMIKILQVLLKFTRFTKTQLPAVEVFLFRYLKTWNGYEFVDEILELITYLKPTSFRELYQYVLKPLSRLYITSDVKWKARLILCYSDWLRNWAALDWKQHVHNRNEATTDVDRLTTFFGHLSFNVDYFQTIQRFVEHVDKLCIAGLLAEEDHVLLQHAGLTFFELVASISRQDDIPDIIIPAATFVHRNFFSTTAMAVSRMCGIIHQYKVAFEENDHKSVNWSSKHTQEYLDHFNTYMMDICNSLWRNLGLCKSKEQAQAFSFTEKNIEQFLELCQDKQVDPKLVLSITHSGALLSLSKRFMEIIEEDEKVNVHHDKPITANYLKELEQEGGVSIGYMEYRVELLDHLTEIGLKGIPDLLYACMNSLIQLKKSAVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-06-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N9J5</accession>
    <name>A0A1C7N9J5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_07941</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000569">
        <property type="protein sequence ID" value="OBZ84014.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N9J5"/>
    <dbReference type="InParanoid" id="A0A1C7N9J5"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ84014.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="76" mass="8242" checksum="440F168CC4895328" modified="2016-11-30" version="1" fragment="single">MKSNQKHKITKSSVRQFNTGRFSATRGFDSSQQSIQNAFNRIQNNVNLSSASASQAVNSSVEEVVTDYSEGGIIGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NAP7</accession>
    <name>A0A1C7NAP7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Heat shock factor protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">hsf1_1</name>
        <name evidence="10" type="ORF">A0J61_05783</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the HSF family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000323">
        <property type="protein sequence ID" value="OBZ86167.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NAP7"/>
    <dbReference type="STRING" id="101091.A0A1C7NAP7"/>
    <dbReference type="InParanoid" id="A0A1C7NAP7"/>
    <dbReference type="OrthoDB" id="60033at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.10:FF:000027">
        <property type="entry name" value="Heat shock transcription factor 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000232">
        <property type="entry name" value="HSF_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10015:SF427">
        <property type="entry name" value="HEAT SHOCK FACTOR PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10015">
        <property type="entry name" value="HEAT SHOCK TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00447">
        <property type="entry name" value="HSF_DNA-bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00056">
        <property type="entry name" value="HSFDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00415">
        <property type="entry name" value="HSF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00434">
        <property type="entry name" value="HSF_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0346">Stress response</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HSF-type DNA-binding" evidence="9">
        <location>
            <begin position="116"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="8"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="46"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006403"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU004020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OBZ86167.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="419" mass="47433" checksum="1239F2E45C8D3ACB" modified="2016-11-30" version="1">MIRHGRVPSLSSISNLSGTSSLASSGSPHSSPINSPYVSPGGSPRESLNNHFSRSMSLQPPTANNNQGNKPNSTNTFVHKLYNMVIDSQYQHLIAWNYTGSSFIVCNIMEFSRDVLPKHFKHNNFSSFVRQLNMYGFHKVNKSPRGHRTSAENQIWEFSHSKFVKDRPEWLDDIKRKSIESDNSSTHRSHHHSDINSHMAMMQVSQSEMVQRLMQLQENFSQVVRELAETKSQQQRQQQMLKNLLDFLSKSGVQFQASSEFNMNGFDHHQQSHSNERPPSIFITSHDATATQQNHIDETTYISQQQQQQYQQQQQAMHIPLSRAQSQQVFTSPVPSISQQQRNQQRLPPALTVQTQNLSTQFSLSPGPNSMDLNSPALSAYHTALNTPVSTISSPFIPDDDIPSLYSPHSPITVVPFPI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NAV3</accession>
    <name>A0A1C7NAV3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Plasma membrane proteolipid 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">pmp-1</name>
        <name evidence="7" type="ORF">A0J61_07434</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the UPF0057 (PMP3) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000501">
        <property type="protein sequence ID" value="OBZ84514.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NAV3"/>
    <dbReference type="STRING" id="101091.A0A1C7NAV3"/>
    <dbReference type="InParanoid" id="A0A1C7NAV3"/>
    <dbReference type="OrthoDB" id="2802411at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000612">
        <property type="entry name" value="PMP3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21659">
        <property type="entry name" value="HYDROPHOBIC PROTEIN RCI2 LOW TEMPERATURE AND SALT RESPONSIVE PROTEIN LTI6 -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21659:SF42">
        <property type="entry name" value="UPF0057 MEMBRANE PROTEIN ZK632.10-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01679">
        <property type="entry name" value="Pmp3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="29"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009530"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OBZ84514.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="78" mass="8711" checksum="326674CEA1F9A29A" modified="2016-11-30" version="1">MIGLCCLILIIVLLPPLGVFFMRGCGADFWINVCLTILGYLPGHIHAFYVLVKERDEGRFREPAYVSNQGQYGAVPPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NB13</accession>
    <name>A0A1C7NB13_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="8">tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">mnmG</name>
        <name evidence="8" type="ORF">A0J61_05647</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Component of the MSS1-MTO1 complex that catalyzes the 5-carboxymethylaminomethyluridine (cmnm(5)U) modification at the 34th wobble position (U34) of mitochondrial tRNAs.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the MnmG family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000311">
        <property type="protein sequence ID" value="OBZ86297.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NB13"/>
    <dbReference type="FunCoup" id="A0A1C7NB13">
        <property type="interactions" value="572"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NB13"/>
    <dbReference type="InParanoid" id="A0A1C7NB13"/>
    <dbReference type="OrthoDB" id="3329at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070899">
        <property type="term" value="P:mitochondrial tRNA wobble uridine modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030488">
        <property type="term" value="P:tRNA methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.50.50.60:FF:000145">
        <property type="entry name" value="tRNA uridine 5-carboxymethylaminomethyl modification enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.150.570:FF:000001">
        <property type="entry name" value="tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.50.50.60:FF:000002">
        <property type="entry name" value="tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.570">
        <property type="entry name" value="GidA associated domain, C-terminal subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00129">
        <property type="entry name" value="MnmG_GidA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049312">
        <property type="entry name" value="GIDA_C_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004416">
        <property type="entry name" value="MnmG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002218">
        <property type="entry name" value="MnmG-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020595">
        <property type="entry name" value="MnmG-rel_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026904">
        <property type="entry name" value="MnmG_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047001">
        <property type="entry name" value="MnmG_C_subdom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044920">
        <property type="entry name" value="MnmG_C_subdom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040131">
        <property type="entry name" value="MnmG_N"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00136">
        <property type="entry name" value="mnmG_gidA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11806">
        <property type="entry name" value="GLUCOSE INHIBITED DIVISION PROTEIN A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11806:SF0">
        <property type="entry name" value="PROTEIN MTO1 HOMOLOG, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01134">
        <property type="entry name" value="GIDA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21680">
        <property type="entry name" value="GIDA_C_1st"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13932">
        <property type="entry name" value="SAM_GIDA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01228">
        <property type="entry name" value="GIDA_assoc_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01280">
        <property type="entry name" value="GIDA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01281">
        <property type="entry name" value="GIDA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="tRNA uridine 5-carboxymethylaminomethyl modification enzyme C-terminal subdomain" evidence="7">
        <location>
            <begin position="604"/>
            <end position="675"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007653"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00054993"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM01228"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OBZ86297.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="688" mass="76730" checksum="C5619879C4FDAF83" modified="2016-11-30" version="1">MYSQIRSRQTARLISRYTYRSSTLHTSVSSQQAIVTQAIPSNYDFDVIVIGGGHAGTEACTAAARSGAKTLLLTQNVNTIGEMSCNPSFGGVGKGVLVREIDALDGVCGRISDLAGIQFKVLNKSKGPAVYGPRAQIDRKLYKKHLHEFLENYPNLTIQAGSVSDLVLNDGMSEPEYQQMVKKGASQLVKGVKLENGQVIRAPNVVITTGTFLGGEIHLGLKTWPAGRIGENPSIGLSNSLRSAGFKLARLKTGTPARLDCRTIDYRGLLVQEGDRPPSPFSYLNKTVPHADNQILCHQTRTNEKVHRYIEQHFDQSIHIRETVKGPRYCPSLESKIKRFRTKEAHNIWLEPEGLDTHIVYPNGISNTMPEDIQVNFLRMIKGLENVEMLKPAYGVEYDHIDPRELKSTLETKRISGLFLAGQINGTTGYEEAAAQGIMAGINAGLHAQGKPPFVLDRSDAYIGVLIDDLITKGVEEPYRVFTARSEYRLLLRADNADTRLTKKGYEAGVVCRERWDHYEASSSALQSAMDALRDIKMSAKRWAEHNISPSTRPSNSLMNDNGVLRSGLDLLTWPNITLNQFEALVPELKDLDPTLQERIMIEGRYKPFLKRQEVEVQSLKRDEHLALDINLDYLQMDQLSNEVRQKLATVRPETLGAAKRIEGMTPAAMVVLMKYAKRKYNTKILDN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NBC6</accession>
    <name>A0A1C7NBC6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Oxidoreductase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">A0J61_05901</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000333">
        <property type="protein sequence ID" value="OBZ86049.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NBC6"/>
    <dbReference type="FunCoup" id="A0A1C7NBC6">
        <property type="interactions" value="56"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NBC6"/>
    <dbReference type="InParanoid" id="A0A1C7NBC6"/>
    <dbReference type="OrthoDB" id="6251714at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016616">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000047">
        <property type="entry name" value="NADP-dependent L-serine/L-allo-threonine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42901">
        <property type="entry name" value="ALCOHOL DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42901:SF1">
        <property type="entry name" value="ALCOHOL DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU000363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OBZ86049.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="284" mass="31414" checksum="36777CAC9F29095E" modified="2016-11-30" version="1">MFRTTFGVLQRRFYHPRLHKKNVLITGASAGIGEACAREFAKEGSNLLLIPFQLKILAARRADKLTRLKDELLDKHKDIEIQTISLDVRKKSHIDDAFSKLDKKDDIDVLVNNAGLVIGLDHLIDVSEEAFDTMFETNVKGLVYVTQAVLPGMKANGKGHIINIGSVAVILVEAFIVTDEQSETATKHAVDAITRSLLFELMDTPIRVSQICPGMVNTEFSTVRFHGDKEKADNVYKGVDPLVGQDIAELVTFTASRPAHVNICDMLVFPTAQAAATTVYRKPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-06-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NBJ4</accession>
    <name>A0A1C7NBJ4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_05473</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000296">
        <property type="protein sequence ID" value="OBZ86477.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NBJ4"/>
    <dbReference type="InParanoid" id="A0A1C7NBJ4"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ86477.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="75" mass="8423" checksum="A71FD1857AA7BE7C" modified="2016-11-30" version="1">MQLAGIGMRSIEFVLFGNNSNVHCIGKSTLNKAWDDNKRDTGFYLTMVPPRTSDAVGETQNLILENKIAPVRQWL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NBN0</accession>
    <name>A0A1C7NBN0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_05474</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000296">
        <property type="protein sequence ID" value="OBZ86471.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NBN0"/>
    <dbReference type="InParanoid" id="A0A1C7NBN0"/>
    <dbReference type="OrthoDB" id="2270958at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="39"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="60"/>
            <end position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ86471.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="96" mass="10228" checksum="7D927866CC90F018" modified="2016-11-30" version="1">MIPQVIRPSVAISKRSLVRTYFASRVSAFNHQEPNYQLEKAHHQAAPLTDSTLYAPQGHTSTPAPNASASSAAASKANESTTATVFTPSVNAVFDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NBZ8</accession>
    <name>A0A1C7NBZ8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Cytoskeletal signaling protein slm1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">slm1_2</name>
        <name evidence="4" type="ORF">A0J61_07071</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000459">
        <property type="protein sequence ID" value="OBZ84884.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NBZ8"/>
    <dbReference type="FunCoup" id="A0A1C7NBZ8">
        <property type="interactions" value="41"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NBZ8"/>
    <dbReference type="InParanoid" id="A0A1C7NBZ8"/>
    <dbReference type="OrthoDB" id="5598057at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046868">
        <property type="entry name" value="BAR_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001849">
        <property type="entry name" value="PH_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046869">
        <property type="entry name" value="SLM1/RGC1-like_PH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31941">
        <property type="entry name" value="CYTOSKELETAL SIGNALING PROTEIN SLM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31941:SF1">
        <property type="entry name" value="CYTOSKELETAL SIGNALING PROTEIN SLM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20400">
        <property type="entry name" value="BAR_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20399">
        <property type="entry name" value="PH_20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00233">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50003">
        <property type="entry name" value="PH_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PH" evidence="3">
        <location>
            <begin position="392"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="513"/>
            <end position="649"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="47"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="623"/>
            <end position="634"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OBZ84884.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="649" mass="73936" checksum="CAF3BEC1DA9884C5" modified="2016-11-30" version="1">MARKKQTTPSVLPHLPKGVAIPEVQLDGNQDLMMPGQKSLPSDDWKNNQLVPSSQNNNAVARRSSTQRHGMPLTERHSKYQMDSEQEPPPMFTAQPNKMSIRRAREGQRQKYIYRMDNGIDPVVLLTDRLEVWRNAIKNLVSYYKKLVTVENKSAKDYLSASKEITLPFPKSNGQFIETGAGGIQDVWGSLRDYTLQHGMLHHESASYTEKAVLPALRAIKHDIKTMITSIQKDKNLRTSIIFESRMQVDRMITHLDKVIEHVYRAPSQADQNTDPFLLNLGIIHAIRELCDHENQLHDNILSLQKETGLFEQKTIENVRYVLSKLREYRLKHKMESPEYIDAVVENFNELKPSDEWNEFVRRHQYNLLRETSAYKTEDMVDYPNKESKYVRATKIGPLELKSGAIRRWTEGVYIITPAGFLHGYKTPKQFQTSPLRPSFSAFVPNLNVEEYEDDDVFELRGDGRRTSVGLGTRYVFRARNSREAQEWLDALHQITDQFEPMPLLANEPFNTTNSAAPVQRDLPPLPESTLPLPGNGNKRKQKMRAIESGPSASNGVGMNGGRDLSTVNEEENGYEKPLPHPSAATGTEHGRGMFAGEHQQHQLADPGTPISPAILPKAMGSKKFDQRPIEEQRNLPMMQPDQDRSLQT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NC44</accession>
    <name>A0A1C7NC44_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Casein kinase II subunit beta</fullName>
            <shortName evidence="3">CK II beta</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">A0J61_05799</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 3">Regulatory subunit of casein kinase II/CK2. As part of the kinase complex regulates the basal catalytic activity of the alpha subunit a constitutively active serine/threonine-protein kinase that phosphorylates a large number of substrates containing acidic residues C-terminal to the phosphorylated serine or threonine.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Tetramer of two alpha and two beta subunits.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the casein kinase 2 subunit beta family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000324">
        <property type="protein sequence ID" value="OBZ86156.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NC44"/>
    <dbReference type="FunCoup" id="A0A1C7NC44">
        <property type="interactions" value="153"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NC44"/>
    <dbReference type="InParanoid" id="A0A1C7NC44"/>
    <dbReference type="OrthoDB" id="2275560at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005956">
        <property type="term" value="C:protein kinase CK2 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034456">
        <property type="term" value="C:UTP-C complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019887">
        <property type="term" value="F:protein kinase regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006359">
        <property type="term" value="P:regulation of transcription by RNA polymerase III"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1820.10:FF:000005">
        <property type="entry name" value="Casein kinase II subunit beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.20.25.20:FF:000001">
        <property type="entry name" value="Casein kinase II subunit beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.25.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1820.10">
        <property type="entry name" value="protein kinase ck2 holoenzyme, chain C, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016149">
        <property type="entry name" value="Casein_kin_II_reg-sub_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035991">
        <property type="entry name" value="Casein_kinase_II_beta-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000704">
        <property type="entry name" value="Casein_kinase_II_reg-sub"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11740">
        <property type="entry name" value="CASEIN KINASE II SUBUNIT BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11740:SF0">
        <property type="entry name" value="CASEIN KINASE II SUBUNIT BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01214">
        <property type="entry name" value="CK_II_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00472">
        <property type="entry name" value="CASNKINASEII"/>
    </dbReference>
    <dbReference type="SMART" id="SM01085">
        <property type="entry name" value="CK_II_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57798">
        <property type="entry name" value="Casein kinase II beta subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01101">
        <property type="entry name" value="CK2_BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00045899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU361268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OBZ86156.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="227" mass="26664" checksum="13CA469760A29753" modified="2016-11-30" version="1">METDRPTSWINWFCSRKRNKYYVEVAESFIEDPFNLIGLSMHISMYKETLEVILDLEPDDAMYNRVPDLSLLEPSAELLYGLIHQRYILTKEGMLSMFEKYITGDFGKCPRVYCNDHYLLPCGQHDLPKQSSVRLYCPNCKDIYIPANPKHHSIDGAHFGTTFPHLFVQAFPECIKYVEPSIYMPKIFGFRVSELSDVGPRMQWLRMITEEQDSENRHLLTDEDEFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NC85</accession>
    <name>A0A1C7NC85_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="12 13">Mitochondrial import inner membrane translocase subunit TIM44</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="primary">tim44</name>
        <name evidence="16" type="ORF">A0J61_05594</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 13">Belongs to the Tim44 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000306">
        <property type="protein sequence ID" value="OBZ86359.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NC85"/>
    <dbReference type="FunCoup" id="A0A1C7NC85">
        <property type="interactions" value="425"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NC85"/>
    <dbReference type="InParanoid" id="A0A1C7NC85"/>
    <dbReference type="OrthoDB" id="10265990at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031314">
        <property type="term" value="C:extrinsic component of mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001405">
        <property type="term" value="C:PAM complex, Tim23 associated import motor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051087">
        <property type="term" value="F:protein-folding chaperone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030674">
        <property type="term" value="F:protein-macromolecule adaptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030150">
        <property type="term" value="P:protein import into mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.450.240:FF:000002">
        <property type="entry name" value="Mitochondrial import inner membrane translocase subunit TIM44"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.450.240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032710">
        <property type="entry name" value="NTF2-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017303">
        <property type="entry name" value="Tim44"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039544">
        <property type="entry name" value="Tim44-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007379">
        <property type="entry name" value="Tim44-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10721">
        <property type="entry name" value="MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM44"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10721:SF1">
        <property type="entry name" value="MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM44"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04280">
        <property type="entry name" value="Tim44"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037871">
        <property type="entry name" value="TIM44"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00978">
        <property type="entry name" value="Tim44"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54427">
        <property type="entry name" value="NTF2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="11 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="10 13" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5 13" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7 13" id="KW-0653">Protein transport</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="9 13" id="KW-0811">Translocation</keyword>
    <keyword evidence="3 13" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Tim44-like" evidence="15">
        <location>
            <begin position="265"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="173"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="14">
        <location>
            <begin position="173"/>
            <end position="191"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004637"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009597"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00074309"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRNR" id="PIRNR037871"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="SMART" id="SM00978"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="OBZ86359.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="425" mass="48359" checksum="325D869A2146E76B" modified="2016-11-30" version="1">MSAYRALLTNTSRTRFAGNAVRYQNTSVRHYSSPFKVFVNTLKEQMSKSKEVKTLQDESSRLNDSEALKKAKEMYEKAKAQQSIQSERLKQATEKLTKAAEKVGSSVNDSFKKASETEFAKDTSEKIKKAAETIDKTVDPLKKSEAVGKITDSFKTVLKDDSGRYGGFVDKETRRKMREEASKTAPKESKTVAENPEAGANLVIHKDSKWKESWNKFKEDSPIMQGIFRARKNYEESDNLFVSYSRAFTDRIADTFGSIFEESDQAQAIRAFQAIDPTFNMDKFMEDARKFIIPELMEAYLKGDVETLKLWCSEATYNVLTAVIQAQMQQGLISDCKIQDMRDIDLVAAKILENDIPVLVLSFRTQEIIVFRNAKSGEIVYGKEDHIEQVTYACVLTKEPEDLQNPITAGWRIIDMAKHDSRPVW</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NCU1</accession>
    <name>A0A1C7NCU1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Queuine tRNA-ribosyltransferase catalytic subunit 1</fullName>
            <ecNumber evidence="6">2.4.2.64</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Guanine insertion enzyme</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">tRNA-guanine transglycosylase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">A0J61_05001</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Catalytic subunit of the queuine tRNA-ribosyltransferase (TGT) that catalyzes the base-exchange of a guanine (G) residue with queuine (Q) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming queuine, allowing a nucleophilic attack on the C1' of the ribose to form the product.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>guanosine(34) in tRNA + queuine = queuosine(34) in tRNA + guanine</text>
            <dbReference type="Rhea" id="RHEA:16633"/>
            <dbReference type="Rhea" id="RHEA-COMP:10341"/>
            <dbReference type="Rhea" id="RHEA-COMP:18571"/>
            <dbReference type="ChEBI" id="CHEBI:16235"/>
            <dbReference type="ChEBI" id="CHEBI:17433"/>
            <dbReference type="ChEBI" id="CHEBI:74269"/>
            <dbReference type="ChEBI" id="CHEBI:194431"/>
            <dbReference type="EC" id="2.4.2.64"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="6">Heterodimer of a catalytic subunit and an accessory subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the queuine tRNA-ribosyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.2.64" evidence="6"/>
    <dbReference type="EMBL" id="LUGH01000258">
        <property type="protein sequence ID" value="OBZ86952.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NCU1"/>
    <dbReference type="FunCoup" id="A0A1C7NCU1">
        <property type="interactions" value="238"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NCU1"/>
    <dbReference type="InParanoid" id="A0A1C7NCU1"/>
    <dbReference type="OrthoDB" id="10249838at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008479">
        <property type="term" value="F:tRNA-guanosine(34) queuine transglycosylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002099">
        <property type="term" value="P:tRNA wobble guanine modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.105">
        <property type="entry name" value="Queuine tRNA-ribosyltransferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00168">
        <property type="entry name" value="Q_tRNA_Tgt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004803">
        <property type="entry name" value="TGT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036511">
        <property type="entry name" value="TGT-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002616">
        <property type="entry name" value="tRNA_ribo_trans-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00430">
        <property type="entry name" value="Q_tRNA_tgt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00449">
        <property type="entry name" value="tgt_general"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43530">
        <property type="entry name" value="QUEUINE TRNA-RIBOSYLTRANSFERASE CATALYTIC SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43530:SF1">
        <property type="entry name" value="QUEUINE TRNA-RIBOSYLTRANSFERASE CATALYTIC SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01702">
        <property type="entry name" value="TGT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51713">
        <property type="entry name" value="tRNA-guanine transglycosylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1 6" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="4 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6 8" id="KW-0808">Transferase</keyword>
    <keyword evidence="3 6" id="KW-0819">tRNA processing</keyword>
    <keyword evidence="5 6" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="tRNA-guanine(15) transglycosylase-like" evidence="7">
        <location>
            <begin position="16"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="region of interest" description="RNA binding" evidence="6">
        <location>
            <begin position="250"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="region of interest" description="RNA binding; important for wobble base 34 recognition" evidence="6">
        <location>
            <begin position="274"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="6">
        <location>
            <position position="95"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="6">
        <location>
            <position position="269"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="95"/>
            <end position="99"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="149"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="192"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="219"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="307"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="309"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="312"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="338"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03218"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01702"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OBZ86952.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="399" mass="44538" checksum="8D39A37251A0F20C" modified="2016-11-30" version="1">MRSALTFKNIATCSTTKARVSIMTLPHGPVDTPVFMPVGTQGTMKGMLPDQLEELNCQILLNNTYHLGLKPGKETLDMIGGSHKFQSWRRNILTDSGGFQMVSLLKLAEITEHGVQFASPHDGSLMMLTPEHSMELQNTIGADIMMQLDDVISSLTTGPRVEEAMWRSIRWLDRCIKAHKKPDTQNLFAIIQGGLDAELRKKCIQEMVKRDLPGYAVGGLSGGEEKDVFWRVVSLCTDLLPKNKPIYCMGVGYAEDLVVCVALGVDMFDCVFPTRTARFGNALTMNGTITMKSGKYASDFGPIEEGCDCSTCKNYTRSFVHLNVTTKDTVGCHLVSIHNIAFQLRLMRSMREAITRDEFPAWIKQFFKGYFGDKSKYPEWCVNALKSVHVDIINDEPSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NCY4</accession>
    <name>A0A1C7NCY4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Vacuolar segregation protein pep7</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">pep7</name>
        <name evidence="8" type="ORF">A0J61_04971</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000256">
        <property type="protein sequence ID" value="OBZ86973.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NCY4"/>
    <dbReference type="FunCoup" id="A0A1C7NCY4">
        <property type="interactions" value="86"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NCY4"/>
    <dbReference type="InParanoid" id="A0A1C7NCY4"/>
    <dbReference type="OrthoDB" id="166134at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd15737">
        <property type="entry name" value="FYVE2_Vac1p_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.860.20">
        <property type="entry name" value="Rabenosyn, Rab binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021565">
        <property type="entry name" value="Rbsn_Rab-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036531">
        <property type="entry name" value="Rbsn_Rab-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000306">
        <property type="entry name" value="Znf_FYVE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017455">
        <property type="entry name" value="Znf_FYVE-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23164">
        <property type="entry name" value="EARLY ENDOSOME ANTIGEN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23164:SF30">
        <property type="entry name" value="EARLY ENDOSOME ANTIGEN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01363">
        <property type="entry name" value="FYVE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11464">
        <property type="entry name" value="Rbsn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00064">
        <property type="entry name" value="FYVE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140125">
        <property type="entry name" value="Rabenosyn-5 Rab-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50178">
        <property type="entry name" value="ZF_FYVE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="FYVE-type" evidence="7">
        <location>
            <begin position="182"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="104"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="405"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="106"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="436"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50178"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OBZ86973.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="436" mass="50084" checksum="437F0D9BCA10AC8F" modified="2016-11-30" version="1" fragment="single">GIESIRLIPVRCGRLCCDEHTQYEIRLNTRAQHDPEHGVWSKVCVECFINRPGYLDHQGVTNSKTSMFLKLREKTIDRVYLESNRLEKRLEKLARIHHATDLQKRPPAITSSSSASLLQPPSLLSHSSSTISLERSDSTSSRDSLGSMLSAKSSFVSNSNSILSMKLKYRDGEQSVIKWEDDRLAKACPLCQSPFTLINRKHHCRLCGKVICGQTRCSKMIPLFTDMSSDTFDDEPVGDTRACRDCQRYVFRRKLKHEEASKPLPIIQLYHQLAITRNNIEKLLPTFHQTILMLEKEKIKTQTHESFKKAAKIRKSLLDNFTLYDTLAKSIKSLPARSACMKRLQANICSAAQMYLQQNMLPLQMLPRILKTNQPVKQHNELEAQLQTYLEQYSLVEGFIQEANMDRKYDDVKTLKSSLEELDQEIRRLKKALVIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NDH1</accession>
    <name>A0A1C7NDH1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">RNA helicase</fullName>
            <ecNumber evidence="2">3.6.4.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">drh-1</name>
        <name evidence="14" type="ORF">A0J61_06528</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the DEAD box helicase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.13" evidence="2"/>
    <dbReference type="EMBL" id="LUGH01000397">
        <property type="protein sequence ID" value="OBZ85424.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NDH1"/>
    <dbReference type="FunCoup" id="A0A1C7NDH1">
        <property type="interactions" value="821"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NDH1"/>
    <dbReference type="InParanoid" id="A0A1C7NDH1"/>
    <dbReference type="OrthoDB" id="196131at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051880">
        <property type="term" value="F:G-quadruplex DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002151">
        <property type="term" value="F:G-quadruplex RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030515">
        <property type="term" value="F:snoRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071042">
        <property type="term" value="P:nuclear polyadenylation-dependent mRNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000184">
        <property type="term" value="P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006369">
        <property type="term" value="P:termination of RNA polymerase II transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd17966">
        <property type="entry name" value="DEADc_DDX5_DDX17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18787">
        <property type="entry name" value="SF2_C_DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000008">
        <property type="entry name" value="ATP-dependent RNA helicase RhlB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000079">
        <property type="entry name" value="probable ATP-dependent RNA helicase DDX17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000629">
        <property type="entry name" value="RNA-helicase_DEAD-box_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014014">
        <property type="entry name" value="RNA_helicase_DEAD_Q_motif"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47958">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE DBP3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00039">
        <property type="entry name" value="DEAD_ATP_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51195">
        <property type="entry name" value="Q_MOTIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 9 14" id="KW-0347">Helicase</keyword>
    <keyword evidence="4 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DEAD-box RNA helicase Q" evidence="13">
        <location>
            <begin position="194"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="11">
        <location>
            <begin position="225"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="12">
        <location>
            <begin position="432"/>
            <end position="577"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="578"/>
            <end position="625"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Q motif" evidence="8">
        <location>
            <begin position="194"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="23"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="44"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="10">
        <location>
            <begin position="68"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="10">
        <location>
            <begin position="581"/>
            <end position="625"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU000492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="OBZ85424.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="625" mass="67739" checksum="E67AD68B3D8A478C" modified="2016-11-30" version="1">MSSYSSSYHHSSSSGGYSSNRGSYRDNRDISPRRSSRPSSSYDNHSRDDRGYSSYRSHPDSSSRNYGHGYGHSSGGGSSSYGGSSSGGGGHSSGAGSSSYGGGSHSYGGGNSGYSNNNSYSYGGGYNKSSSSYGQSGSTDSKEIHWDLSTLPKFEKNFYTEHPDVARRTPEEVEAIRAAAGMIVTGHAVPKPLKTFEEANFPSYVMDELNKLGFAQPTPIQCQGWPMALSGHDVVGVAETGSGKTLAYILPAILHINAQPLLQPGDGPIVLVLAPTRELAVQIREECVKFGSTSRIKNTCLYGGTPRGPQIRDLARGVEICIATPGRLIDMLDGGKTNLKRVTYLVLDEADRMLDMGFEPQIRKIINQIRPDRQTLMWSATWPKTVERLAQSYLKDFIQVTVGSLSLSASNNVSQTVEICTEQEKRGKLITQLERIMESPENERKTIIFTSTKRTADDITRFLRQDGFPALAIHGDKQQNERDWVLNQFRSGGHPIMVATDVASRGIDVKDVKYVINYDFPTNIEDYVHRVGRTGRGGNTGHSFTYFTTENARQARELVDILNQTNQYVDPRLQMMVQSRGSGGGRGGGRGGFRGRGRGGYGGGSRGGGYGGGSYGGSGGGSSRW</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NDL2</accession>
    <name>A0A1C7NDL2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit WBP1</fullName>
            <shortName evidence="8">Oligosaccharyl transferase subunit WBP1</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">DDOST</name>
        <name evidence="11" type="ORF">A0J61_04776</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER).</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 8">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Component of the oligosaccharyltransferase (OST) complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Endoplasmic reticulum membrane</location>
            <topology evidence="8">Single-pass type I membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass type I membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the DDOST 48 kDa subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000241">
        <property type="protein sequence ID" value="OBZ87171.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NDL2"/>
    <dbReference type="FunCoup" id="A0A1C7NDL2">
        <property type="interactions" value="626"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NDL2"/>
    <dbReference type="InParanoid" id="A0A1C7NDL2"/>
    <dbReference type="OrthoDB" id="29105at2759"/>
    <dbReference type="UniPathway" id="UPA00378"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008250">
        <property type="term" value="C:oligosaccharyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018279">
        <property type="term" value="P:protein N-linked glycosylation via asparagine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005013">
        <property type="entry name" value="DDOST_48_kDa_subunit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055459">
        <property type="entry name" value="OST48_MD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055457">
        <property type="entry name" value="OST48_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10830">
        <property type="entry name" value="DOLICHYL-DIPHOSPHOOLIGOSACCHARIDE--PROTEIN GLYCOSYLTRANSFERASE 48 KDA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10830:SF0">
        <property type="entry name" value="DOLICHYL-DIPHOSPHOOLIGOSACCHARIDE--PROTEIN GLYCOSYLTRANSFERASE 48 KDA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23358">
        <property type="entry name" value="OST48_MD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03345">
        <property type="entry name" value="OST48_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <keyword evidence="11" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008810991" description="Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit WBP1" evidence="8">
        <location>
            <begin position="22"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="364"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="domain" description="OST48 N-terminal" evidence="9">
        <location>
            <begin position="28"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="domain" description="OST48 middle" evidence="10">
        <location>
            <begin position="251"/>
            <end position="386"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008743"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU361142"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF03345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF23358"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="OBZ87171.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="398" mass="45064" checksum="3B81F6EC24B1D759" modified="2016-11-30" version="1">MRVIYSLTAIVLSGLSVLVQAKSTTGDRVLVLLDSLAEKETYSQFWQQLEEGDLTRLIDRDFQLVFKAADDQKTTLAYFGETLYQHIIHFAPSTSSLEKHPSLSNVQLVNFVNNGGNLLAAFNQPSDTLRALAAEFDMDLETEVRDQSAKLVGPKTIVDPEQISAPVKFTGAGLQVGKLPLSHAILASNNQALVGTLQSRNSARVAFAGSLSMFSNDYMNADSTGNKAFVRQLSQWTFQEKSVLKVTQHGHHHLNDTEQPAWYRVKDEMVYYADIMEYKDDTWIPYEANDVQLEIIMLDPYIRTTLKSHNGRFEAQLRLPDVYGVFTLKVNYKRAGLSYLTAEDQVSIRPFRHNEYPRFLTAAYPYYASTLSMIVGFILFSAVWLSTWNQEEKTKKKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NDN2</accession>
    <name>A0A1C7NDN2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Alkylated DNA repair protein alkB 8</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">alkbh8</name>
        <name evidence="2" type="ORF">A0J61_05272</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000281">
        <property type="protein sequence ID" value="OBZ86666.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NDN2"/>
    <dbReference type="STRING" id="101091.A0A1C7NDN2"/>
    <dbReference type="InParanoid" id="A0A1C7NDN2"/>
    <dbReference type="OrthoDB" id="271595at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032451">
        <property type="term" value="F:demethylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070988">
        <property type="term" value="P:demethylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.590">
        <property type="entry name" value="Alpha-ketoglutarate-dependent dioxygenase AlkB-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027450">
        <property type="entry name" value="AlkB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037151">
        <property type="entry name" value="AlkB-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032857">
        <property type="entry name" value="ALKBH4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005123">
        <property type="entry name" value="Oxoglu/Fe-dep_dioxygenase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12463:SF1">
        <property type="entry name" value="2-OXOGLUTARATE AND FE-DEPENDENT OXYGENASE FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12463">
        <property type="entry name" value="OXYGENASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13532">
        <property type="entry name" value="2OG-FeII_Oxy_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51471">
        <property type="entry name" value="FE2OG_OXY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fe2OG dioxygenase" evidence="1">
        <location>
            <begin position="98"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ86666.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="205" mass="22885" checksum="0A9CFA7CBCEC5A0A" modified="2016-11-30" version="1" fragment="single">ETQVPGLLVIKEFVNKSEELELIDAVDKQPWSGLGIGEEHNNTGICLVTDIGMALTITQMGHSLNSATRKVLEEYGPLPEFSQLLVDRIMQHQLMPNIPNHLLVNEYNAGQGIMPHIDAPALFGPAILSLSLLSDCIMKFTLEEKEVDVVLPRRSIAVLTGDARYTYKHSISKDLVETTPDGTLIHRDRRVSFTFREIIAWEVPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NEE8</accession>
    <name>A0A1C7NEE8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">RNA polymerase II transcription factor SIII subunit A3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">TCEB3C</name>
        <name evidence="2" type="ORF">A0J61_04475</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000220">
        <property type="protein sequence ID" value="OBZ87475.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NEE8"/>
    <dbReference type="FunCoup" id="A0A1C7NEE8">
        <property type="interactions" value="36"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NEE8"/>
    <dbReference type="InParanoid" id="A0A1C7NEE8"/>
    <dbReference type="OrthoDB" id="21513at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070449">
        <property type="term" value="C:elongin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006368">
        <property type="term" value="P:transcription elongation by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.3180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051870">
        <property type="entry name" value="Elongin-A_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010684">
        <property type="entry name" value="RNA_pol_II_trans_fac_SIII_A"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15141">
        <property type="entry name" value="TRANSCRIPTION ELONGATION FACTOR B POLYPEPTIDE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15141:SF76">
        <property type="entry name" value="TRANSCRIPTION ELONGATION FACTOR B POLYPEPTIDE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06881">
        <property type="entry name" value="Elongin_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="218"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="224"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="243"/>
            <end position="262"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ87475.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="280" mass="32228" checksum="C23C4ED8C0D86C52" modified="2016-11-30" version="1">MSNKQVKSLVTACQDTLTKYLDILTDVGCVPYSLLKPAIAHATAQQLYRIEKANPVCSFALTEDIAAESDELWLKHCLMFKDIRDEHQQGLHRDPKKWRELYLHTHHENEKKRQMIKEKVKSQYSKIKNEKEKKSIKVLHGVVPTKGRHSYEAARRSTMSKLFQQTRKETNKVASIYHSLSSSTKRPIQPISSSTTTVIHVPKPASRLVQSYRDNQTKHIRNPYSPPLPPLTPPKSHFIPSREQPEPASKRPRLKDDSNCDVKKKKPTAMVNFNIFNELS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NEU0</accession>
    <name>A0A1C7NEU0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Myb-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">A0J61_04683</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000234">
        <property type="protein sequence ID" value="OBZ87269.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="FunCoup" id="A0A1C7NEU0">
        <property type="interactions" value="4"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NEU0"/>
    <dbReference type="InParanoid" id="A0A1C7NEU0"/>
    <dbReference type="OrthoDB" id="68020at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000127">
        <property type="term" value="C:transcription factor TFIIIC complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042791">
        <property type="term" value="P:5S class rRNA transcription by RNA polymerase III"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006384">
        <property type="term" value="P:transcription initiation at RNA polymerase III promoter"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001005">
        <property type="entry name" value="SANT/Myb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046488">
        <property type="entry name" value="Sfc3/Tfc3_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044210">
        <property type="entry name" value="Tfc3-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007309">
        <property type="entry name" value="TFIIIC_Bblock-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15180">
        <property type="entry name" value="GENERAL TRANSCRIPTION FACTOR 3C POLYPEPTIDE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15180:SF1">
        <property type="entry name" value="GENERAL TRANSCRIPTION FACTOR 3C POLYPEPTIDE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04182">
        <property type="entry name" value="B-block_TFIIIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20222">
        <property type="entry name" value="DUF6581"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50090">
        <property type="entry name" value="MYB_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <feature type="domain" description="Myb-like" evidence="8">
        <location>
            <begin position="1617"/>
            <end position="1675"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="75"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="663"/>
            <end position="768"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="785"/>
            <end position="1007"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="1182"/>
            <end position="1225"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="130"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="164"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="676"/>
            <end position="685"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="708"/>
            <end position="721"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="800"/>
            <end position="822"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="823"/>
            <end position="835"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="845"/>
            <end position="860"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="877"/>
            <end position="887"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="921"/>
            <end position="931"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="939"/>
            <end position="956"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="966"/>
            <end position="978"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="990"/>
            <end position="999"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OBZ87269.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="2241" mass="255177" checksum="9E4054FA685A3957" modified="2016-11-30" version="1">MLDTLKQRVKEEIAIDGDTGSNINDVWKYVQQILKEVASQSNVSITPLVDERYKQFFWKYLAAESDLTFYESANEVTPMEEDTSQSIPEADEQPLSSKPDSVDQPTEEPIGNSEVTQQQVEEDEEEILANKKRKRPPPKKKKKPVAKKPKKKKAAKKKRVAVGDSDDDFVDDDVSESSSESEFDELISSEEEEPQEEEEDVDLLLRKHMPKGRREPPSIYQKSHPKTIETGQKTRVNKQDLKLIQDIQQLSYEQVVEKYGDRLIIIASAELQEEQLYVNVPPGNILSPNLVAVLKEIIKTRKEGLYQANITKLLQLDSRSTGHYVKSLEEKGAITRSGVSINSMYTNICIHARFNGEKTKLDMNTVGNDKKSNQIPYNVNAYGKVYSQRMVLDAFVEFAQGAPNKIIVARDVLHALGFDSTRRQVQKWYNRVIDEICMKGYFKKHNVQVEEKGHRFRGLELLNEPIDKSTTNVTTSVDAVELPIRIESNQKDIPVIHLLWDLSVEAQCLQVISAAGANGVTQKDISFALNIDEQRVMNKALEHLVDPKSHVNDRYRVVRFLEFDRRLKRYRYYTKAAHLKMTENIDLPPQPMPSPGLDISKCYERNIFYDAPHDTTNFNKFIDLYVKARTNKNTVLNALHASTSYNGFAGKPVSVSKTRLAKSLTAKKTNQREGTRSQTLHTNSVDKPADQAPSSSISLDPSPVLSVTEDSQTLPSSTIIDETTIIKRKRGRPAGSGKGGKASTKKPRKSAGQTTVEVEQQPKLPNPAESSIATRFAIQEQINTQKETVPFNDIPEDQPKPQTESIIPDDSTNQSVSENRNNVPVEPVIAVEAPAQSAPMEATNASESSLPAASEPIAEPMIVDSNKETASNDQRESTPSSQTSSKGTSKKKTIADYFKRAPKKPSVPVEKTPSPVPAAQESETTSVSPSIISVEKEANQLTEEATKNNVESTEQASAEPMDICEPSSTEPLSNNPADQTAHLAPEEQAEPSTCESSTMEEPHGETSHNDLLQSLAVDNFDYDRLCSYDSTVPQGKQSRILVNGVWVYHHKPKHRRNPYAAARMKAMVMIVWKRRMTEFDRDFRNEYLKILGTLNTVHKGTVCNKTIWKTALDAQEEGLVKTNVVTISLLSGATIDRKTIIRGDIDLEGEEYQKFVSLMKDRKVLSTSQYGFSSTGVTNIPVERLDARLARMQEEANNQQDVAKAKLMEERVSELSKNLNLFSRKKQAAAPLAWMISALQFGWIQAIMVRARILYEQIIRLLDTDTEGVFPEERLMNATTIIKSMSVGTVCQIIGLHQPSKRLASFVKDPDNADLVFDQLPTEIRAELFGEPNKFRRRLRVIFQVLQYIEVITPVFPGESEGQSRPAYVEYAPQYRVEPVVEIRDRRIVGEPIRYVKHVNNVEDARSLFSDLQYVYVNPSAHPSPESSVASLPEDPVLLQLFKTTHNRNNWSTTSVFSAERRKHINTYIDKKNFTTPLDNTTLMRQISREADCPIYALRLYYQKAQALLNQKKLKSELQYVMSRSRNSGKRVRRGKRVDLFDGRRVIKKDSAHAFVSRKYERHLIVLPHVDMETVRSHTEENEKFAAKRSKGELLFMDDMKDLPVLPSDDNASHLRKPRGKRFVWTRRDDELLMYANIVLRQRTGRQRFSWIPIVKQFFPETPFSSCRHRYTKLMRLAEWKELFETHTYLWHKIYDEGLAKGEIEDKDPEDNINCDLLGLVTYFIQKLSENTPENLPSDNQPLPKTIQEFHANLEIANRPNKSFSYLHDAFHESHTMARKTQVLYSQAFNLHRYDAKRLDQSEAAIESDLDKNSRDAKLCRSFALMSLMTPSEYYDPFYCYSVFQQFPKRILDDTFKKMRDDGTLVLTSQDRPIPGTRFSLSEKFMRCMAGQLPNNIFQQANEYEKFLRQQNGMIRFTSDYASSGMIACLLNLVSDNKLSMAPVNLNRILKAMSEENFHIRSIDARLVRFDINVEILEKEDQVIPYMPSAEQPQIKQLGASAFNMELEKLLESQDGWFGELLKQIVDLLYNEAENGLTLYQLKSKVDSIYTDENVMHAIHVLYTNQPILICRVGFEAVRYVHISFAKSWTISTNVSRYDVSNVKIRGAIEEASKKVDLCERKELIVPSIWTDANGSTTDVILRDCKDFLVDLILNKPGITEADIYRQAEMALSKRELRDVLNMLVEQQVLRQVCLSFPPKAVKKASVFNRLRTISCKNNNSIENVTQSCFWVTSKPYAFLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NEU6</accession>
    <name>A0A1C7NEU6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">1,3-beta-glucan synthase</fullName>
            <ecNumber evidence="3">2.4.1.34</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">FKS1_0</name>
        <name evidence="13" type="ORF">A0J61_04318</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>[(1-&gt;3)-beta-D-glucosyl](n) + UDP-alpha-D-glucose = [(1-&gt;3)-beta-D-glucosyl](n+1) + UDP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:21476"/>
            <dbReference type="Rhea" id="RHEA-COMP:11146"/>
            <dbReference type="Rhea" id="RHEA-COMP:14303"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:37671"/>
            <dbReference type="ChEBI" id="CHEBI:58223"/>
            <dbReference type="ChEBI" id="CHEBI:58885"/>
            <dbReference type="EC" id="2.4.1.34"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the glycosyltransferase 48 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.34" evidence="3"/>
    <dbReference type="EMBL" id="LUGH01000209">
        <property type="protein sequence ID" value="OBZ87635.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="FunCoup" id="A0A1C7NEU6">
        <property type="interactions" value="193"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NEU6"/>
    <dbReference type="InParanoid" id="A0A1C7NEU6"/>
    <dbReference type="OrthoDB" id="1880850at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000148">
        <property type="term" value="C:1,3-beta-D-glucan synthase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003843">
        <property type="term" value="F:1,3-beta-D-glucan synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006075">
        <property type="term" value="P:(1-&gt;3)-beta-D-glucan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051278">
        <property type="term" value="P:fungal-type cell wall polysaccharide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026899">
        <property type="entry name" value="FKS1-like_dom1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056261">
        <property type="entry name" value="FKS1-like_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003440">
        <property type="entry name" value="Glyco_trans_48_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12741:SF48">
        <property type="entry name" value="1,3-BETA-GLUCAN SYNTHASE COMPONENT FKS1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12741">
        <property type="entry name" value="LYST-INTERACTING PROTEIN LIP5 DOPAMINE RESPONSIVE PROTEIN DRG-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14288">
        <property type="entry name" value="FKS1_dom1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23605">
        <property type="entry name" value="FKS1_dom2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02364">
        <property type="entry name" value="Glucan_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01205">
        <property type="entry name" value="FKS1_dom1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="8 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="6 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="506"/>
            <end position="525"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="537"/>
            <end position="560"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="580"/>
            <end position="600"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="612"/>
            <end position="635"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="666"/>
            <end position="688"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="716"/>
            <end position="734"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="1358"/>
            <end position="1377"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="1410"/>
            <end position="1431"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="1521"/>
            <end position="1545"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="1612"/>
            <end position="1637"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="1658"/>
            <end position="1691"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="1697"/>
            <end position="1720"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="1805"/>
            <end position="1830"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="1853"/>
            <end position="1877"/>
        </location>
    </feature>
    <feature type="domain" description="1,3-beta-glucan synthase component FKS1-like" evidence="12">
        <location>
            <begin position="350"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="943"/>
            <end position="969"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="18"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="69"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="102"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="952"/>
            <end position="965"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012589"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00047777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM01205"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="OBZ87635.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="1893" mass="216089" checksum="8538DB6A75A632E4" modified="2016-11-30" version="1">MEESTSLSKDDTGHNEAASEQSGLSTSHNNTSKNSIASNTNTHRKKPAAPAQDFPEIRAYYANIAEKPQGSRHDMDKSTDSLDSSRVDSEVSSIASASFKLTAEDKFKQPKEHQKSEHLTPRTFEFPTQYASAPMSHPNSPNVIVVPSKPDASNIDVLAALTEGDDGRYLEYASSADSMLALLESRKYTGNKANKSTNNSEASIQKPIKTDDPTFNTLIGYATENSPYPAWGPEDTIPIPFSQVDSIFESLQKKFGFQKDSTHNMAEHLKIMLDSRASRLNPQLALDTLHADYIGGENANYRKWFFASKMDLYDQTEQEKQIATDIGDEQEQLSRMEEKWTLRMRALTNTEKIRDLALYLCLWGEAAPVRFTPETLCFIFKMGYDYYCHNDPSLLPDLEEGSYLQQIVTPLYHFFRDQTYVLMNGKYVKREKDHDQVIGYDDVNQFFWHSTFYDRIQVSGDSTLGKLQPHERYSALKDVDWQKTFRKTYKEKRTWMHASINFSRVWVIHIVTFWYYIMANAYSLYLDPEKEIAEQEVSVQISIVALGGVVACLLILIGSFAELAYLPASWSNSKKVMRRISFLFILMILNAAPSFYCVVIDRKSWISKTVSIVQLLFSVGTTLFLSIVPSSRLFMRTSKHTREQLANERFTANFPSLKPIDRVMSISLWICVFTCKLLESYFFLALSFKDPLQVISKMTITNCNDKLIGSMLCEQMPRITIFIMLLMDLVLYFLDTYLWYIIWNTIFSVARSFYLGISIWSPWRNIFSRLPKRIFVKLLATSDIHVKYKPKVLCSQIWNAIVITMYREHLITVDHAQRMLYQQELNPMSGQRTLKTPTFFVSQEDTSFKTEYFPQRGEAERRIQFFAQSLTTPMPPPHPVECMPTFTVLTPHYGEKIMLTLREIIREEDTSTRVTLLEYLKQLHTVEWENFVKDTKMLVGDDDRRNLTNNQSEGSVISSASSQSSFEKDMPKSNAIDDLPFYCIGFKSSKPEYTLRTRIWASLRAQTLYRTVSGFMNYRKAIKLLYRVENPESLQHYGDDRDALEKDLDKLSRRKFKFLVAMQRYAKFSPSESEDAEFMFKAFPDLQVAYIDEEPPTEPDGEITYYSALIDGYCPHDENGKRIPRYRIRLPGNPIIGDGKSDNQNHAIIFYRGEFLQLVDANQDNYLEECLKIRNVLGEFETLEPCNISPYAPTFPKSRGQSPVAIVGAREYIFSENIGVLGDVAAGKEQTFGTLTQRIMAKIGGKLHYGHPDFLNAIFMTTRGGISKAQKGLHLNEDIYAGMNAFTRGGRIKHTEYFQCGKGRDLGFGSILNFTTKIGTGMGEQMLSREYYYIGTQLPLDRFLTFYYAHPGFHINNIFIMMSVQMFMLAILFISAMGSTLTICEYNADAPPDAPLIPEGCHNLVPIFDWVKRCILSIVAVFFAAFLPLFLQELTERGFLRSLSRMGRHFISLSPLFEIFVTQIYTNSVLENLVFGGARYIGTGRGFATSRLPFSTLYSRFTGPSIYVGARNLIVMLFASLAYWIPHLIYFWFTVLALIVSPFVFNPNQFAPIDFLVDYREFIHWLSRGNSKTHRDSWISHTRSARARITGYKRSKPTEATKSVGDVPRAGIGSIFVSEVLLPFFYAMLCLIPYTFIKSFDPTDSTLPASGPSAFIRIGVMAFAPILINVVGLAIFFGVSVGLGSFLSIWIVKFGSTVAALAHAWSVIGAIITFEALFVLEGWKLSNVVLGLVSIVAVQRFIIRLLTVVCLTREFKHDESNRGWWTGKWYGRGLGWHALSQPGREFICKIIEMTEFATDFLLGHLILFFLSIFILIPYINTAHSLMLFWLRPSEQIRSHIWTAKERRQRKRTAITYGIMFYSLFLLFVGLVIAPAILGPSLLSGLVNVKKLPI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NEW8</accession>
    <name>A0A1C7NEW8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Iron-sulfur cluster co-chaperone protein HscB, mitochondrial</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">HSCB</name>
        <name evidence="4" type="ORF">A0J61_04296</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the HscB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000207">
        <property type="protein sequence ID" value="OBZ87655.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NEW8"/>
    <dbReference type="FunCoup" id="A0A1C7NEW8">
        <property type="interactions" value="286"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NEW8"/>
    <dbReference type="InParanoid" id="A0A1C7NEW8"/>
    <dbReference type="OrthoDB" id="448954at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001671">
        <property type="term" value="F:ATPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051087">
        <property type="term" value="F:protein-folding chaperone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044571">
        <property type="term" value="P:[2Fe-2S] cluster assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051259">
        <property type="term" value="P:protein complex oligomerization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.20">
        <property type="entry name" value="HscB, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004640">
        <property type="entry name" value="HscB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036386">
        <property type="entry name" value="HscB_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009073">
        <property type="entry name" value="HscB_oligo_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00714">
        <property type="entry name" value="hscB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14021">
        <property type="entry name" value="IRON-SULFUR CLUSTER CO-CHAPERONE PROTEIN HSCB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14021:SF15">
        <property type="entry name" value="IRON-SULFUR CLUSTER CO-CHAPERONE PROTEIN HSCB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07743">
        <property type="entry name" value="HSCB_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47144">
        <property type="entry name" value="HSC20 (HSCB), C-terminal oligomerisation domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0143">Chaperone</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="J" evidence="3">
        <location>
            <begin position="84"/>
            <end position="163"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010476"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OBZ87655.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="251" mass="29272" checksum="5A54F522D14A54F4" modified="2016-11-30" version="1">MNTRNWCQLLRAATTTLTRTRVALNIQKIRAAPVSRQFSTSLSWRSSMVQEKKCWQCQAPNKPSSLFCESKSCSVIQPIPPSLNYFNLLQVGEGQEKEKPSFNIDLKALKKRFLILQQKAHPDSYSQAAKQELDYAQLQSSIINKAYNTLKNPLSRAQYILKQQGIEVDESESLNDPELLMEVMEFREELEEVSSEEELKPLKQRNDERYQETVNRLQDAFEKQDYDRAKELAIELQYWTSIQNAIHEWHP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NF39</accession>
    <name>A0A1C7NF39_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_06014</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000344">
        <property type="protein sequence ID" value="OBZ85934.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NF39"/>
    <dbReference type="InParanoid" id="A0A1C7NF39"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ85934.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="70" mass="8209" checksum="3B023D62E584ED95" modified="2016-11-30" version="1">MSNSTSSRSVGNMPAFFEREEAESHDEEPVVEDHPDEFVDYEHEHDEKQNPLVKICKKGHKLFHVKRSEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-06-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NF94</accession>
    <name>A0A1C7NF94_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_04320</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000209">
        <property type="protein sequence ID" value="OBZ87630.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NF94"/>
    <dbReference type="InParanoid" id="A0A1C7NF94"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ87630.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="91" mass="10542" checksum="A3335AF16C1FF782" modified="2016-11-30" version="1">MLVPRILNQKGQPDKPKGLPVYILTFCPLFRYPNAIELLRHGFKANDIASKNTTIAKLALIGLQLRLQLFIDIDFNWLQCSIVRYFATLYF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NGJ1</accession>
    <name>A0A1C7NGJ1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_03849</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000175">
        <property type="protein sequence ID" value="OBZ88100.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NGJ1"/>
    <dbReference type="InParanoid" id="A0A1C7NGJ1"/>
    <dbReference type="OrthoDB" id="20273at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ88100.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="84" mass="9953" checksum="5F87802670B6AAD1" modified="2016-11-30" version="1">MPLFKIRTKSKVTSDFNFTPPTEAKPVQNAYSSFNRMDSPTSTLQEIRSEAPSYYSRVYMQQQQQQQQHYDRFQGTCIEQNYKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NGL4</accession>
    <name>A0A1C7NGL4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Inorganic phosphate transport protein PHO88</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">PHO88_2</name>
        <name evidence="3" type="ORF">A0J61_03717</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000165">
        <property type="protein sequence ID" value="OBZ88242.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NGL4"/>
    <dbReference type="FunCoup" id="A0A1C7NGL4">
        <property type="interactions" value="129"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NGL4"/>
    <dbReference type="InParanoid" id="A0A1C7NGL4"/>
    <dbReference type="OrthoDB" id="18139at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045047">
        <property type="term" value="P:protein targeting to ER"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012098">
        <property type="entry name" value="SND3_fun"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28112">
        <property type="entry name" value="SRP-INDEPENDENT TARGETING PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28112:SF1">
        <property type="entry name" value="SRP-INDEPENDENT TARGETING PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10032">
        <property type="entry name" value="Pho88"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="41"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="171"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="174"/>
            <end position="196"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ88242.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="196" mass="22578" checksum="9ED16AAD195B6410" modified="2016-11-30" version="1">MPDWNRVLNHPVSNIGFFYVVRQVIKTFGLDDPSYLGLIRFIYLCSQILVLVFTFYLLSVIRKKNDTTPLRYVEPGGQSWNGSETTDKLVTTTVTEYDIQETKKQMQTNFTSIAIIAFLHLKFGYVQPLIMQSILGFKTFFMTKEARIHFFHASTSSGELRRPFRIEGPLSLLSEKRQPKTDKGSIKRAEKALKAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NGW9</accession>
    <name>A0A1C7NGW9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Replication factor A protein 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">ssb3</name>
        <name evidence="4" type="ORF">A0J61_03588</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the replication factor A protein 3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000157">
        <property type="protein sequence ID" value="OBZ88362.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NGW9"/>
    <dbReference type="FunCoup" id="A0A1C7NGW9">
        <property type="interactions" value="80"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NGW9"/>
    <dbReference type="InParanoid" id="A0A1C7NGW9"/>
    <dbReference type="OrthoDB" id="188186at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005662">
        <property type="term" value="C:DNA replication factor A complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035861">
        <property type="term" value="C:site of double-strand break"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003684">
        <property type="term" value="F:damaged DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006284">
        <property type="term" value="P:base-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000724">
        <property type="term" value="P:double-strand break repair via homologous recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006298">
        <property type="term" value="P:mismatch repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006289">
        <property type="term" value="P:nucleotide-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd04479">
        <property type="entry name" value="RPA3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013970">
        <property type="entry name" value="Rfa2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15114:SF1">
        <property type="entry name" value="REPLICATION PROTEIN A 14 KDA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15114">
        <property type="entry name" value="REPLICATION PROTEIN A3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08661">
        <property type="entry name" value="Rep_fac-A_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009761"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OBZ88362.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="104" mass="11638" checksum="3C4DBA75684C24CB" modified="2016-11-30" version="1">MDKPTPRINSALREKYVGRVVRLVGKLHSLSGNTAVLDASDHGQVMVKLNGESQWGTDYVEVIGQIESDYTLREFKTSNLGNSFDLDMANKVVEYSQKLPSMFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NHV1</accession>
    <name>A0A1C7NHV1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Mitochondrial GTP/GDP carrier protein 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">A0J61_03245</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000136">
        <property type="protein sequence ID" value="OBZ88703.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NHV1"/>
    <dbReference type="FunCoup" id="A0A1C7NHV1">
        <property type="interactions" value="242"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NHV1"/>
    <dbReference type="InParanoid" id="A0A1C7NHV1"/>
    <dbReference type="OrthoDB" id="409947at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001409">
        <property type="term" value="F:guanine nucleotide transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006879">
        <property type="term" value="P:intracellular iron ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="FunFam" id="1.50.40.10:FF:000010">
        <property type="entry name" value="Probable YHM1 (Mitochondrial carrier)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053042">
        <property type="entry name" value="Mito_GTP/GDP_Carrier"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46974">
        <property type="entry name" value="MITOCHONDRIAL GTP/GDP CARRIER PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46974:SF1">
        <property type="entry name" value="MITOCHONDRIAL GTP_GDP CARRIER PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 10 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 11" id="KW-0813">Transport</keyword>
    <feature type="repeat" description="Solcar" evidence="10">
        <location>
            <begin position="221"/>
            <end position="303"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU000488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="OBZ88703.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="14">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="312" mass="33954" checksum="149A6FA0E626FD93" modified="2016-11-30" version="1">MSPPVASGSSESGMARFAGSASSGILELIIFHPVDTVAKRLMSNQNKLWSPARSFAENKALVDQVVFKEAANATFLKKYASLFPGLGFAAGYKVAQRVYKFGGQPFVKDYLNKNHKDLFVNTFGEKTGKTVMHAFAGSLVGIGEIALLPLDVLKIKRQTNPEAFRGRGFLKIVSDEGMGLYRGAGWTAARNAPGSFALFGGSAFVKEYIFHLEDYNKATFFQNFCSSIGGAVASITVAAPLDVVKTRIQNRNFENPESGLKIIKDLVKNEGFGGFFKGLTPKILVVGPKLIFSFTVAQQLIPVFHKMFEGQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NIF7</accession>
    <name>A0A1C7NIF7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Mitochondrial metalloendopeptidase OMA1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">oma1</name>
        <name evidence="9" type="ORF">A0J61_03144</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="6">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the peptidase M48 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000130">
        <property type="protein sequence ID" value="OBZ88808.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NIF7"/>
    <dbReference type="FunCoup" id="A0A1C7NIF7">
        <property type="interactions" value="136"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NIF7"/>
    <dbReference type="InParanoid" id="A0A1C7NIF7"/>
    <dbReference type="OrthoDB" id="7464992at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034982">
        <property type="term" value="P:mitochondrial protein processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006515">
        <property type="term" value="P:protein quality control for misfolded or incompletely synthesized proteins"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07331">
        <property type="entry name" value="M48C_Oma1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2010.10">
        <property type="entry name" value="Metalloproteases ('zincins'), catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051156">
        <property type="entry name" value="Mito/Outer_Membr_Metalloprot"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001915">
        <property type="entry name" value="Peptidase_M48"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22726">
        <property type="entry name" value="METALLOENDOPEPTIDASE OMA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22726:SF1">
        <property type="entry name" value="METALLOENDOPEPTIDASE OMA1, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01435">
        <property type="entry name" value="Peptidase_M48"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 6" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="1 6" id="KW-0645">Protease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4 6" id="KW-0862">Zinc</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="60"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M48" evidence="8">
        <location>
            <begin position="128"/>
            <end position="300"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003983"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01435"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OBZ88808.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="351" mass="40565" checksum="028D315ADE41EC67" modified="2016-11-30" version="1">MLTRILQPVKSTLLTGIRLPKQRYASYSRFPLQPIKNQPPSNYTRFQNNQRIPFYLSKRVWVFVGTGTVMFGGYYVTHLERVPISNRVRFMDVTPRQEEAMAIQAYHEVMAQFGRRILPANHPYSRFVRKVAQRLVRVSGMDHMKWEFYVIDSPERNAFVLPGGKVFVFTGILPVVQNEDGMAAVLGHEISHQLARHSAEKFSFVKILFALQFTLTLFGIDPSFIFNQFSLSFLMMKPFSRKCETEADDIGLQLMALACFNPQEAIEVWKRMDAMGEHEIPQFASTHPSHKNRIEFLRKEVGLGMHHLLSFLIHSLPNIKLPAAMKKRAESDCSSQMKTFADQFADTWARW</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NIG8</accession>
    <name>A0A1C7NIG8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="12">ATP-binding cassette sub-family D member 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">ABCD2_1</name>
        <name evidence="12" type="ORF">A0J61_03620</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ABC transporter superfamily. ABCD family. Peroxisomal fatty acyl CoA transporter (TC 3.A.1.203) subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000159">
        <property type="protein sequence ID" value="OBZ88336.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NIG8"/>
    <dbReference type="STRING" id="101091.A0A1C7NIG8"/>
    <dbReference type="InParanoid" id="A0A1C7NIG8"/>
    <dbReference type="OrthoDB" id="422637at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005778">
        <property type="term" value="C:peroxisomal membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005324">
        <property type="term" value="F:long-chain fatty acid transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006635">
        <property type="term" value="P:fatty acid beta-oxidation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015910">
        <property type="term" value="P:long-chain fatty acid import into peroxisome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007031">
        <property type="term" value="P:peroxisome organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042760">
        <property type="term" value="P:very long-chain fatty acid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd03223">
        <property type="entry name" value="ABCD_peroxisomal_ALDP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="entry name" value="ABC transporter type 1, transmembrane domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050835">
        <property type="entry name" value="ABC_transporter_sub-D"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11384:SF67">
        <property type="entry name" value="ATP-BINDING CASSETTE SUB-FAMILY D MEMBER 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11384">
        <property type="entry name" value="ATP-BINDING CASSETTE, SUB-FAMILY D MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06472">
        <property type="entry name" value="ABC_membrane_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="ABC transporter transmembrane region"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 12" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="12"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="84"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="127"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="11">
        <location>
            <begin position="92"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="10">
        <location>
            <begin position="438"/>
            <end position="670"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="661"/>
            <end position="691"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008575"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="OBZ88336.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="696" mass="78814" checksum="A509BD9DB2553A16" modified="2016-11-30" version="1">MPMLSTLNSPHTKALSGSVFFSAILITLYKTKQFYLRHKDTNQDLAGLFPIINFSQKVGVNKEFKRQLSAIATILFPHWHTKEALLLVLHSIFLVLRTYLSVVVARLDGRIVKDLVNGNGKQFLVGLGYWFAIAIPATYTNSMIRYLQSKLSIGFRTRLTRYIHDLYLDHQKTFYKAINLDSRIQGGADQFITTDIAKFCDTLASLYSNLAKPILDTVIFNYQLTKSIGFTGMVGLMINYAITARLLRAVTPSFGKLAAIEAQLEGDFRAAHARLITNAEEVGFYNGSELEHSILNKAYLKLIKHINSIYKTRISYNMFEDFLIKYAWSAFGLIMCAVPVFGPEWAKTEKVENEQVGVRTKAFITNKRLMMSLADAGGRMMYSYKELAELAGYTSRVYNLLSVLHAIHDNQFDGPRKPKQFTLTHIHGTLIVDSEKGIVFDNVPIVTPAPGQERVGEVLVNNLNVHVRPGEHLLITGPNGVGKTAVARVIASLWPVFEGKLTRPRDGDIFYIPQRPYLSLGSLRDQVIYPHTHEQMRASGRTDEDLMDILKVVHLAYIPDREGGWETEKEWKDVFSGGEKQRIGMARLFYHHPKFAVLDECTSAVSTDVEGLMYSHAKDMGITLLTISHRPALFKYHRFLLRLTGNQGQWEWETIGTREQLQSVEKELSMLQTQVDQVDALKARLAQIDTELSLRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NIH1</accession>
    <name>A0A1C7NIH1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Ubiquitin carboxyl-terminal hydrolase</fullName>
            <ecNumber evidence="6">3.4.19.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">UBP2_0</name>
        <name evidence="9" type="ORF">A0J61_03125</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).</text>
            <dbReference type="EC" id="3.4.19.12"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the peptidase C19 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.19.12" evidence="6"/>
    <dbReference type="EMBL" id="LUGH01000129">
        <property type="protein sequence ID" value="OBZ88825.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NIH1"/>
    <dbReference type="FunCoup" id="A0A1C7NIH1">
        <property type="interactions" value="39"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NIH1"/>
    <dbReference type="InParanoid" id="A0A1C7NIH1"/>
    <dbReference type="OrthoDB" id="2420415at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004843">
        <property type="term" value="F:cysteine-type deubiquitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070628">
        <property type="term" value="F:proteasome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043161">
        <property type="term" value="P:proteasome-mediated ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016579">
        <property type="term" value="P:protein deubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061136">
        <property type="term" value="P:regulation of proteasomal protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.70.10">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001394">
        <property type="entry name" value="Peptidase_C19_UCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044635">
        <property type="entry name" value="UBP14-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028889">
        <property type="entry name" value="USP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018200">
        <property type="entry name" value="USP_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43982">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43982:SF6">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00443">
        <property type="entry name" value="UCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00972">
        <property type="entry name" value="USP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00973">
        <property type="entry name" value="USP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50235">
        <property type="entry name" value="USP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4 6 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 6" id="KW-0645">Protease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 6" id="KW-0788">Thiol protease</keyword>
    <keyword evidence="3 6" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="USP" evidence="8">
        <location>
            <begin position="39"/>
            <end position="540"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="387"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="443"/>
            <end position="470"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU366025"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OBZ88825.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="553" mass="64692" checksum="0A92AE2BAE65D1D5" modified="2016-11-30" version="1">MQHNKEFFHFGLNISHAPKKEISNNKKLASKTRKNKRPVGLSNIGNTCYFNSLVQYYYTIVSFRETMVHYKNCVEDENNTGSIKVDQSKIPRAKRFVALLKDLFCNIRHCKKSAISPEYNLACMALLNEEEDGVQEEKITKFTKESPSQLVEQNDINNSSQINVDDDVQNTENIESVDIEMTEAIQGNSDYQYAFNEAAVNDKDILLVDSPSYKSIGSEQRTKHLLLDAKKHKQKEELNVNSMMFGRQQDLTECMGNIMYLVEAALKTKDGKQVDDVVRQTFYGKTCQILSYYDDTTLQKIKKEQEEDFAYIIVNTKEGSNLYEVMDNYFFANQVNFQGGHDATREVIVKSFPPILQIHIQRVQFNRELVHAYKSNAHVQFDKVIYLDRYTEELKDKRAQLATWRAELDKITQRVKKAEKFLVKRSKEEMKQIGHNLKLVALFKEYRRLIKRDNRKIKKLEKKIQTQYKDHTKVAYKLHAVFIHQGQANYGHYWVYILDHAKDQWWKYNDSLVTEVDENEIFHSTTGSATNPYFLAYVDANRIEEYVETIPQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NIL1</accession>
    <name>A0A1C7NIL1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Prefoldin subunit 3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">A0J61_04773</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2 4">Heterohexamer of two PFD-alpha type and four PFD-beta type subunits.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the prefoldin subunit alpha family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000241">
        <property type="protein sequence ID" value="OBZ87174.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NIL1"/>
    <dbReference type="FunCoup" id="A0A1C7NIL1">
        <property type="interactions" value="616"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NIL1"/>
    <dbReference type="InParanoid" id="A0A1C7NIL1"/>
    <dbReference type="OrthoDB" id="6375174at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016272">
        <property type="term" value="C:prefoldin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015631">
        <property type="term" value="F:tubulin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007017">
        <property type="term" value="P:microtubule-based process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007021">
        <property type="term" value="P:tubulin complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd23156">
        <property type="entry name" value="Prefoldin_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.370:FF:000001">
        <property type="entry name" value="Prefoldin subunit 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.370">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016655">
        <property type="entry name" value="PFD3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009053">
        <property type="entry name" value="Prefoldin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004127">
        <property type="entry name" value="Prefoldin_subunit_alpha"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12409">
        <property type="entry name" value="PREFOLDIN SUBUNIT 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12409:SF0">
        <property type="entry name" value="PREFOLDIN SUBUNIT 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02996">
        <property type="entry name" value="Prefoldin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016396">
        <property type="entry name" value="Prefoldin_subunit_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46579">
        <property type="entry name" value="Prefoldin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0143">Chaperone</keyword>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="134"/>
            <end position="161"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRNR" id="PIRNR016396"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OBZ87174.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="187" mass="21620" checksum="C97CE9457D097126" modified="2016-11-30" version="1">MSEQKLETNPRGIPSSPFVERVEDYVSEAEPVEVVLKKFQEAISKYKFMEINLLQRRKVLEEKIPEIEKTIAMVDLLAEKKETEEPLYTDFELNDTLYAKAKVEASGTVYLWLGANVMLEYTFEEAKDLLTSKLDTAKKSLKNTLEDLEFLRSQITTMEVNTARVYNWDVKQRRLLREQAGSVEATA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-06-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NJZ8</accession>
    <name>A0A1C7NJZ8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_02632</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000101">
        <property type="protein sequence ID" value="OBZ89318.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NJZ8"/>
    <dbReference type="InParanoid" id="A0A1C7NJZ8"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ89318.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="74" mass="8260" checksum="62F0DC6907FF9014" modified="2016-11-30" version="1">MPNSGLNETIPKFDQTTARSTNNGCQISVLQIHHRIFHYPFSTIGVTLGYYPFSTIGVTLVPMLSTEAFSNHFI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NK10</accession>
    <name>A0A1C7NK10_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Alpha-1,3-glucosyltransferase</fullName>
            <ecNumber evidence="11">2.4.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">ALG8</name>
        <name evidence="13" type="ORF">A0J61_03126</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>an alpha-D-Glc-(1-&gt;3)-alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;6)]-alpha-D-Man-(1-&gt;6)]-beta-D-Man-(1-&gt;4)-beta-D-GlcNAc-(1-&gt;4)-alpha-D-GlcNAc-diphospho-di-trans,poly-cis-dolichol + a di-trans,poly-cis-dolichyl beta-D-glucosyl phosphate = an alpha-D-Glc-(1-&gt;3)-alpha-D-Glc-(1-&gt;3)-alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;6)]-alpha-D-Man-(1-&gt;6)]-beta-D-Man-(1-&gt;4)-beta-D-GlcNAc-(1-&gt;4)-alpha-D-GlcNAc-diphospho-di-trans,poly-cis-dolichol + a di-trans,poly-cis-dolichyl phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:31307"/>
            <dbReference type="Rhea" id="RHEA-COMP:19498"/>
            <dbReference type="Rhea" id="RHEA-COMP:19502"/>
            <dbReference type="Rhea" id="RHEA-COMP:19521"/>
            <dbReference type="Rhea" id="RHEA-COMP:19522"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57525"/>
            <dbReference type="ChEBI" id="CHEBI:57683"/>
            <dbReference type="ChEBI" id="CHEBI:132521"/>
            <dbReference type="ChEBI" id="CHEBI:132522"/>
            <dbReference type="EC" id="2.4.1.265"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="10">
            <dbReference type="Rhea" id="RHEA:31308"/>
        </physiologicalReaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 11">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 11">Endoplasmic reticulum membrane</location>
            <topology evidence="1 11">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 11">Belongs to the ALG6/ALG8 glucosyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.-" evidence="11"/>
    <dbReference type="EMBL" id="LUGH01000129">
        <property type="protein sequence ID" value="OBZ88826.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NK10"/>
    <dbReference type="FunCoup" id="A0A1C7NK10">
        <property type="interactions" value="447"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NK10"/>
    <dbReference type="InParanoid" id="A0A1C7NK10"/>
    <dbReference type="OrthoDB" id="1689333at2759"/>
    <dbReference type="UniPathway" id="UPA00378"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042283">
        <property type="term" value="F:dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006488">
        <property type="term" value="P:dolichol-linked oligosaccharide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004856">
        <property type="entry name" value="Glyco_trans_ALG6/ALG8"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12413">
        <property type="entry name" value="DOLICHYL GLYCOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12413:SF2">
        <property type="entry name" value="DOLICHYL PYROPHOSPHATE GLC1MAN9GLCNAC2 ALPHA-1,3-GLUCOSYLTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03155">
        <property type="entry name" value="Alg6_Alg8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 11" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="4 11" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="9 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="12" id="KW-0732">Signal</keyword>
    <keyword evidence="5 11 13" id="KW-0808">Transferase</keyword>
    <keyword evidence="6 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="12">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008889740" description="Alpha-1,3-glucosyltransferase" evidence="12">
        <location>
            <begin position="22"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="90"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="121"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="144"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="166"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="218"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="305"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="340"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="379"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="407"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="440"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="473"/>
            <end position="493"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008715"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00047346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU363110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="OBZ88826.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="495" mass="56629" checksum="759E75797AC6D38F" modified="2016-11-30" version="1">MRHLLIISTLIKLLLIPAYRSTDFEVHRNWLAITHSLPISKWYIENTSEWTLDYPPFFAWFEKFLSIFGAFVDSNMVKVENLGYASTETILFQRLTVIVTELVLYWALMRARYTKYFGDKYVHWVTAGSLFMHPGLIIVDHIHFQYNGLLYGILILSIVEAKRNNLLASGAIFAILLNFKHIYLYLAPAYFVYLLKAYCFVSSSKIDKKHNSFSLTRLITLGSAVVAIFAISFSPFIYLGQIPNLLSRLFPFTRGLCHAYWAPNFWALYAGLDRCLIILAKRLAWEFDSNAVTSMTRGYVGDTQFAVLPTVEAIHTLLLTVFVQLVVLQKLWRKPTFNNFLASLTLCGFASYLFGWHVHEKAIMIVLLPYGLMAANSQIHLRIFVVLSSAGIFSLYPLLFHATETPIKIAATLLWFCATLPGLAYSVKTPLRNLLSVIELYYLAGFFFLQAYTGCLHDLLFGQNLEFLPLMLTSLYCAVGIVYGWGLFMWNYLCT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NKH6</accession>
    <name>A0A1C7NKH6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_02390</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000089">
        <property type="protein sequence ID" value="OBZ89565.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NKH6"/>
    <dbReference type="InParanoid" id="A0A1C7NKH6"/>
    <dbReference type="OrthoDB" id="10561926at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017956">
        <property type="entry name" value="AT_hook_DNA-bd_motif"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02178">
        <property type="entry name" value="AT_hook"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00929">
        <property type="entry name" value="ATHOOK"/>
    </dbReference>
    <dbReference type="SMART" id="SM00384">
        <property type="entry name" value="AT_hook"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="48"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="59"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="87"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="103"/>
            <end position="115"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ89565.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="115" mass="12737" checksum="5F919A4560BDAD23" modified="2016-11-30" version="1">MPSTGISTKAEVTLDKEAKTNIPPARKRGRPSKDAVKGLGQEIPQDSMKGKSEEKAEQQVESLNVSQNEQPQKRKRGRPPKVLSEAEVMKREAKKKVDPSVPKRGRGRPRKAPSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NL09</accession>
    <name>A0A1C7NL09_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_02433</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000092">
        <property type="protein sequence ID" value="OBZ89509.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NL09"/>
    <dbReference type="STRING" id="101091.A0A1C7NL09"/>
    <dbReference type="InParanoid" id="A0A1C7NL09"/>
    <dbReference type="OrthoDB" id="128536at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ89509.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="82" mass="9484" checksum="C98DDED9C78BC954" modified="2016-11-30" version="1" fragment="single">MSESLNELFPQLVSMTDADKILKLARHMPCDQCQDCQGWRPSFSLDYSQTCLCGHDANEHVGQKRDFTRRLKVALRIDELLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NLF5</accession>
    <name>A0A1C7NLF5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Exportin-2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">cse1l</name>
        <name evidence="9" type="ORF">A0J61_03829</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the XPO2/CSE1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000174">
        <property type="protein sequence ID" value="OBZ88124.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NLF5"/>
    <dbReference type="FunCoup" id="A0A1C7NLF5">
        <property type="interactions" value="956"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NLF5"/>
    <dbReference type="InParanoid" id="A0A1C7NLF5"/>
    <dbReference type="OrthoDB" id="3268246at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005635">
        <property type="term" value="C:nuclear envelope"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034399">
        <property type="term" value="C:nuclear periphery"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032991">
        <property type="term" value="C:protein-containing complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005049">
        <property type="term" value="F:nuclear export signal receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031267">
        <property type="term" value="F:small GTPase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046827">
        <property type="term" value="P:positive regulation of protein export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006611">
        <property type="term" value="P:protein export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006606">
        <property type="term" value="P:protein import into nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061015">
        <property type="term" value="P:snRNA import into nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.10.10:FF:000057">
        <property type="entry name" value="Exportin-2 isoform 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001494">
        <property type="entry name" value="Importin-beta_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005043">
        <property type="entry name" value="XPO2_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013713">
        <property type="entry name" value="XPO2_central"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10997:SF8">
        <property type="entry name" value="EXPORTIN-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10997">
        <property type="entry name" value="IMPORTIN-7, 8, 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03378">
        <property type="entry name" value="CAS_CSE1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08506">
        <property type="entry name" value="Cse1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03810">
        <property type="entry name" value="IBN_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00913">
        <property type="entry name" value="IBN_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50166">
        <property type="entry name" value="IMPORTIN_B_NT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Importin N-terminal" evidence="8">
        <location>
            <begin position="27"/>
            <end position="102"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008669"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50166"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OBZ88124.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="986" mass="112775" checksum="2E8E4017BFA580F1" modified="2016-11-30" version="1">MEINEQTYATLQQYLLQTLNPATQKEAAFNLSQVEVQQGFPMLLLKAISDEAGDMTIRMAGAVYFKNYIKRNWVLENENEADKIALQDRLEIKRQIVQLMITVPDKLQLQISDALSLIAASDFPEKWDTLLPELISKLSPTDYRVNNGILGTAHSIFKRWRSAFRSDELFLSIKYVLDLFCEPYMQLFQITDKLIEENSNNVQALQILARSLILLIKIYYDLNCQDLPEFFEDNLTTFMGLFEKYLVYQNPLLATDDEEEEGPLEQIKTGICYILELYASRYEEAFPQLNIFVPIVINLLTNTNGDSKYDTTVCKAFSVLSVIVRIDRHSDYFANEATLSTMCERIALPNIAIRASDEELYEDNPIEYIRRDLEGSDHDTRRRAAADFIRGLMERFETQVTKIMSEYVGQYVGRFLQNYNANPKANWKDKNTAIFLLVAIATRSSTLQLGVTKTNELVDVVDFFSKHVLCDLQSEVNADIPILKMDAIKYVYTFRNQLTKEQLLTVFPLLVKHLESTDYVVHTYAAIAIERILFIRQGKTMMFTATDIKPYTETLLTQLFRLIELGQTPEKLSENDYLMRAVMRVIITSRQDMEPYVTAIMTKLTHILAIVSKNPSNPKFNHYVFESIGALIRFICPISEGALSQFENLCFGPFQTILSQEVQEFSPYVFQLLAQLLEQHKGNELTPAYMALLTPLLNPSLWEQGNIPALVRLMQAYLDKGAQTILANNQFEPILGIFQQKLVYSRQFDHYGMLLLETITKRIPLSVLGNYLPVLCNAVLKRLLSKKKGDEITFDRFTRNFTLWMCTCFLAESMNGPDSIIRVFETIQPGLFGQVMNFFVLPDLSKLHKPIDRRIASVGVTHLLTRSDSMVSPPYSEELWPKSMFALLALLELPAVAETDGPDELYTLDIEEGGYQTTFAKLATSHPIQEDPTANLPISQIYLVQQLVAMPVEKRNVARGLCSKLPEATQCLPAYFERANIPLTQF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NM84</accession>
    <name>A0A1C7NM84_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_03576</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000157">
        <property type="protein sequence ID" value="OBZ88374.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NM84"/>
    <dbReference type="InParanoid" id="A0A1C7NM84"/>
    <dbReference type="OrthoDB" id="2275486at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="73"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="74"/>
            <end position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ88374.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="150" mass="17115" checksum="148DF0BC198AA11F" modified="2016-11-30" version="1">MSHDVQVNSKLLKCIVCHKQFARYDQRGFRNPGFTAHQNRCIDRRYQSKTKLKPKLKPRPNLRTLLPAPVRHSGSMQRLARQSNPSYSTKSTLATAPIGSTTSFDSRITTSAVTNEFVFADIQCNYCIPQFGRHRISCLFAAKNMNHRDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NMH3</accession>
    <name>A0A1C7NMH3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">6-pyruvoyltetrahydropterin synthase</fullName>
            <ecNumber evidence="4">4.2.3.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">pts</name>
        <name evidence="9" type="ORF">A0J61_01683</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Cofactor biosynthesis; tetrahydrobiopterin biosynthesis; tetrahydrobiopterin from 7,8-dihydroneopterin triphosphate: step 1/3.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the PTPS family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.3.12" evidence="4"/>
    <dbReference type="EMBL" id="LUGH01000056">
        <property type="protein sequence ID" value="OBZ90275.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NMH3"/>
    <dbReference type="STRING" id="101091.A0A1C7NMH3"/>
    <dbReference type="InParanoid" id="A0A1C7NMH3"/>
    <dbReference type="OrthoDB" id="14045at2759"/>
    <dbReference type="UniPathway" id="UPA00849">
        <property type="reaction ID" value="UER00819"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003874">
        <property type="term" value="F:6-pyruvoyltetrahydropterin synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006729">
        <property type="term" value="P:tetrahydrobiopterin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.479.10:FF:000003">
        <property type="entry name" value="6-pyruvoyl tetrahydrobiopterin synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.479.10">
        <property type="entry name" value="6-pyruvoyl tetrahydropterin synthase/QueD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007115">
        <property type="entry name" value="6-PTP_synth/QueD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038418">
        <property type="entry name" value="6-PTP_synth/QueD_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12589:SF7">
        <property type="entry name" value="6-PYRUVOYL TETRAHYDROBIOPTERIN SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12589">
        <property type="entry name" value="PYRUVOYL TETRAHYDROBIOPTERIN SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01242">
        <property type="entry name" value="PTPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55620">
        <property type="entry name" value="Tetrahydrobiopterin biosynthesis enzymes-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0456">Lyase</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0783">Tetrahydrobiopterin biosynthesis</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013100"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OBZ90275.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="143" mass="16834" checksum="1C3CA8256FC00E1F" modified="2016-11-30" version="1">MPIAYITRSERSITAHRLHSPELTEEQNKLIYGKCNHPHFHGHNYKVEITMKGEIDPLTGMVMNLVDLKECIQLAVMDHLDHRNLDLDVPFFQSRASTTENLAVYVWSNFQYYYQQKFSSHSAQLYKVKIYETEKNMVEYYGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NMT2</accession>
    <name>A0A1C7NMT2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Homoserine O-acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">metE</name>
        <name evidence="6" type="ORF">A0J61_01688</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the AB hydrolase superfamily. MetX family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000056">
        <property type="protein sequence ID" value="OBZ90280.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NMT2"/>
    <dbReference type="FunCoup" id="A0A1C7NMT2">
        <property type="interactions" value="145"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NMT2"/>
    <dbReference type="InParanoid" id="A0A1C7NMT2"/>
    <dbReference type="OrthoDB" id="191364at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004414">
        <property type="term" value="F:homoserine O-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071266">
        <property type="term" value="P:'de novo' L-methionine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009092">
        <property type="term" value="P:homoserine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00296">
        <property type="entry name" value="MetX_acyltransf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008220">
        <property type="entry name" value="HAT_MetX-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01392">
        <property type="entry name" value="homoserO_Ac_trn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF001209">
        <property type="entry name" value="PRK00175.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32268">
        <property type="entry name" value="HOMOSERINE O-ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32268:SF11">
        <property type="entry name" value="HOMOSERINE O-ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000443">
        <property type="entry name" value="Homoser_Ac_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="5">
        <location>
            <begin position="66"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="253"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="3">
        <location>
            <position position="160"/>
        </location>
    </feature>
    <feature type="active site" evidence="3">
        <location>
            <position position="361"/>
        </location>
    </feature>
    <feature type="active site" evidence="3">
        <location>
            <position position="390"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006886"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR000443-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OBZ90280.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="450" mass="50256" checksum="4AB30992AFA3A1DC" modified="2016-11-30" version="1">MQTFKTYATLNELPFEESKNNLAKLIPDQNITIIPEYTLESGVRMKNVPIAWKSWGKLNEKADNCMVICHALTGSADVEDWWGPLMGPKRAFDATKFFIVCCNVLGSPYGSASPLTINSETGDKYGPEFPLVSVRDDVQLHRLVLDYLGVKQVAICIGGSMGGMQVLEWAQLGQDYVRCIVPIATSGRHSAWGISWGEAQRQSIYSDPNYLDGYYTEEAPPVVGLSAARMSALLTYRSRNSFESRFGRKAAELKSLQRRPSSPGEANRMIHNDGHRASSPPLAEAEKESINNPSMPQPFVFSAQSYLRYQGTKFVNRFDANCYIALTRKMDSHDISRGKGDYFEVLHSVTQPALVIGIESDGLFTISEQYELAEGMANTEMVVIDSPDGHDGFLLEFDQINRHILSFIKRVLPEIFNTTTVSEEEVEQTENLKATKTSLFGEAEVDITQW</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NMU8</accession>
    <name>A0A1C7NMU8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Dynamin-binding protein</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Scaffold protein Tuba</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="primary">DNMBP_0</name>
        <name evidence="13" type="ORF">A0J61_02144</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell junction</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Golgi apparatus</location>
            <location evidence="2">Golgi stack</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000077">
        <property type="protein sequence ID" value="OBZ89806.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NMU8"/>
    <dbReference type="FunCoup" id="A0A1C7NMU8">
        <property type="interactions" value="5"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NMU8"/>
    <dbReference type="InParanoid" id="A0A1C7NMU8"/>
    <dbReference type="OrthoDB" id="10256089at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005795">
        <property type="term" value="C:Golgi stack"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005085">
        <property type="term" value="F:guanyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035556">
        <property type="term" value="P:intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031991">
        <property type="term" value="P:regulation of actomyosin contractile ring contraction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032955">
        <property type="term" value="P:regulation of division septum assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00160">
        <property type="entry name" value="RhoGEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00174">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.60">
        <property type="entry name" value="Arfaptin homology (AH) domain/BAR domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.900.10">
        <property type="entry name" value="Dbl homology (DH) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.40">
        <property type="entry name" value="SH3 Domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027267">
        <property type="entry name" value="AH/BAR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004148">
        <property type="entry name" value="BAR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035899">
        <property type="entry name" value="DBL_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000219">
        <property type="entry name" value="DH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051492">
        <property type="entry name" value="Dynamin-Rho_GEF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001331">
        <property type="entry name" value="GDS_CDC24_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036028">
        <property type="entry name" value="SH3-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001452">
        <property type="entry name" value="SH3_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22834">
        <property type="entry name" value="NUCLEAR FUSION PROTEIN FUS2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22834:SF20">
        <property type="entry name" value="SH3 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03114">
        <property type="entry name" value="BAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00621">
        <property type="entry name" value="RhoGEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00018">
        <property type="entry name" value="SH3_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00325">
        <property type="entry name" value="RhoGEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00326">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103657">
        <property type="entry name" value="BAR/IMD domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48065">
        <property type="entry name" value="DBL homology domain (DH-domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50044">
        <property type="entry name" value="SH3-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51021">
        <property type="entry name" value="BAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00741">
        <property type="entry name" value="DH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50010">
        <property type="entry name" value="DH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50002">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0965">Cell junction</keyword>
    <keyword evidence="5" id="KW-0344">Guanine-nucleotide releasing factor</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0728">SH3 domain</keyword>
    <feature type="domain" description="DH" evidence="11">
        <location>
            <begin position="252"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="domain" description="BAR" evidence="12">
        <location>
            <begin position="451"/>
            <end position="665"/>
        </location>
    </feature>
    <feature type="domain" description="SH3" evidence="10">
        <location>
            <begin position="761"/>
            <end position="824"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="54"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="187"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="699"/>
            <end position="744"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="9">
        <location>
            <begin position="62"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="190"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="706"/>
            <end position="721"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="722"/>
            <end position="733"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="734"/>
            <end position="744"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004348"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00018186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022658"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022949"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00032587"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51021"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="OBZ89806.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="824" mass="94105" checksum="75C9D2E8595F3C36" modified="2016-11-30" version="1">MSSLPDAFSKTLDSKPRNSYISQLRQEQHINNATHSGSSTVNRLSRVFEASTHLEHTGYKPKPTPPAKPPSLKPLPNQTPRIKPEIDETSLDFKDIRARFQQDTTIRQPLKPSMTGPPSPPEKMIIASKTGPPALPVKPKVIHHRSIEQTYRPYPQQPTPSDSFIENQQRGSLSSVYLPSMVHRTATGNSSIMSTTSTSSQTSNSTHSKRGWHISNWFSNQQQQQLDHETLKNSIKRSNTIEIVSPQVTGSKRAKVMHELLETEKTFQKDMTLLKEIYFDGAHHAGFSKSDIRYLFSNLTEIVEFEKTFVIMMELTCEQDSIGTCFREMMRSIDTIYSEYCKRQEDAVLRLQELESQPHVQTFLNDCKEKIQGKTTSWDLGSLLIKPVQRVLKYPLLLRELLVLTPSTHDDYDNLSAAVKEIQDVADNINEIKRRKDIVEKIVGDKKRTEMSATGFAIEPTHDILFEALYEKFEEQQEMVRQLAREVQGWVRHVKISFENLQQLACSMEALYSSWGGVRVKSLNAVTDFSKMANHMYNNLARELDNDVRGYVYSRIDDFLKVFENPTQVINKRALKMIDYDRVRDMKLKGDVPDKALQESADAYVSINGQLVDELPKFFALTSQYIDILLGEIAFVQIKFNGSMQKEWTKLVEQNLGSRVAESYESIVQTYAIQFDKVEDMANKITILNRNRYQSSIANSGSLKNKSRDSSSFKLTTDHDSSISSPIHSNHSIVTSSSRAPTPITPVTENMIDMDYDTNLAQDFDCVMLYDFNTDDEDQLSAKSGTILRISQDPDFIDEEWWYATTLDDSHQSGWVPINYCKKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NMW1</accession>
    <name>A0A1C7NMW1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Chitin deacetylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">CDA_14</name>
        <name evidence="5" type="ORF">A0J61_01468</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000047">
        <property type="protein sequence ID" value="OBZ90482.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NMW1"/>
    <dbReference type="InParanoid" id="A0A1C7NMW1"/>
    <dbReference type="OrthoDB" id="407355at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004099">
        <property type="term" value="F:chitin deacetylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009272">
        <property type="term" value="P:fungal-type cell wall biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.370">
        <property type="entry name" value="Glycoside hydrolase/deacetylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011330">
        <property type="entry name" value="Glyco_hydro/deAcase_b/a-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002509">
        <property type="entry name" value="NODB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050248">
        <property type="entry name" value="Polysacc_deacetylase_ArnD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10587:SF133">
        <property type="entry name" value="CHITIN DEACETYLASE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10587">
        <property type="entry name" value="GLYCOSYL TRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01522">
        <property type="entry name" value="Polysacc_deac_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88713">
        <property type="entry name" value="Glycoside hydrolase/deacetylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51677">
        <property type="entry name" value="NODB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008889797" evidence="3">
        <location>
            <begin position="20"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="domain" description="NodB homology" evidence="4">
        <location>
            <begin position="151"/>
            <end position="357"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OBZ90482.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="368" mass="41865" checksum="DD4EDE1C2F62918D" modified="2016-11-30" version="1">MLNTKITTCIILSLSLIHGLPRSHPTLQARGVTLTSSNILPMHSPAFLPKFPPLNLKPVQPPPTGPIQRISRLRRQDYPENWVSPDIQHPEVQAAIKSIDWEHVPKLKPQTGGDSSYDIDQDEACWWTRSQCTTPKVSYLPEDVSACPKRGDFALTYDDGPLSPQRPNDPWAEPRLYDFLALHHQRATLFYIGSNVVAFPDAAIRAYQSGHTLCAHTWSHPKMTSLTNEAIVAELYWSVRAIKEATGVTPRCWRPPYGDVDDRVRAIAHQFGFYTLLWNSDSFDWGLPSSANGFGGVYTQDQVDSYFQAWVNERNEDTDEEGRVVLEHETSNMTVLTSERWLEKLQKVFRVKTMHECEPLLPGPYWEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NN49</accession>
    <name>A0A1C7NN49_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">E3 ubiquitin ligase complex SCF subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">sconC</name>
        <name evidence="6" type="ORF">A0J61_02048</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Essential component of the SCF (SKP1-CUL1-F-box protein) E3 ubiquitin ligase complexes, which mediate the ubiquitination and subsequent proteasomal degradation of target proteins.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Component of the SCF (SKP1-CUL1-F-box protein) E3 ubiquitin ligase complexes.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the SKP1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000073">
        <property type="protein sequence ID" value="OBZ89896.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NN49"/>
    <dbReference type="FunCoup" id="A0A1C7NN49">
        <property type="interactions" value="545"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NN49"/>
    <dbReference type="InParanoid" id="A0A1C7NN49"/>
    <dbReference type="OrthoDB" id="2342932at2759"/>
    <dbReference type="UniPathway" id="UPA00143"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043224">
        <property type="term" value="C:nuclear SCF ubiquitin ligase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043291">
        <property type="term" value="C:RAVE complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017117">
        <property type="term" value="C:single-stranded DNA-dependent ATP-dependent DNA helicase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0101026">
        <property type="term" value="P:mitotic nuclear membrane biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045841">
        <property type="term" value="P:negative regulation of mitotic metaphase/anaphase transition"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016567">
        <property type="term" value="P:protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000018">
        <property type="term" value="P:regulation of DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000712">
        <property type="term" value="P:resolution of meiotic recombination intermediates"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031146">
        <property type="term" value="P:SCF-dependent proteasomal ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd18322">
        <property type="entry name" value="BTB_POZ_SKP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.710.10:FF:000026">
        <property type="entry name" value="E3 ubiquitin ligase complex SCF subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016897">
        <property type="entry name" value="SKP1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001232">
        <property type="entry name" value="SKP1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036296">
        <property type="entry name" value="SKP1-like_dim_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016072">
        <property type="entry name" value="Skp1_comp_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016073">
        <property type="entry name" value="Skp1_comp_POZ"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11165">
        <property type="entry name" value="SKP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01466">
        <property type="entry name" value="Skp1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03931">
        <property type="entry name" value="Skp1_POZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF028729">
        <property type="entry name" value="E3_ubiquit_lig_SCF_Skp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00512">
        <property type="entry name" value="Skp1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54695">
        <property type="entry name" value="POZ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81382">
        <property type="entry name" value="Skp1 dimerisation domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0436">Ligase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="SKP1 component POZ" evidence="5">
        <location>
            <begin position="1"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="domain" description="SKP1 component dimerisation" evidence="4">
        <location>
            <begin position="105"/>
            <end position="152"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009993"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRNR" id="PIRNR028729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF03931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OBZ89896.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="155" mass="17871" checksum="4FD3BB205C2C5D37" modified="2016-11-30" version="1">MSVTLLSSDLEQFKVDKDVAERSVLIKNMLEDIGDSDAPIPLPNVSSKVLTKVIEWCTHHRDDPVTQDDQERRNTDIDEWDQKYMEVDQETLFDVILAANYLDIKPLLDVGCKTVANMIKGKSAEEIRRTFNITNDFTPDEEAQIKKENEWAEDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NNU2</accession>
    <name>A0A1C7NNU2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Protein-serine/threonine kinase</fullName>
            <ecNumber evidence="8">2.7.11.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">pkp1_1</name>
        <name evidence="10" type="ORF">A0J61_01403</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>L-seryl-[pyruvate dehydrogenase E1 alpha subunit] + ATP = O-phospho-L-seryl-[pyruvate dehydrogenase E1 alpha subunit] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:23052"/>
            <dbReference type="Rhea" id="RHEA-COMP:13689"/>
            <dbReference type="Rhea" id="RHEA-COMP:13690"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.2"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Mitochondrion matrix</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 8">Belongs to the PDK/BCKDK protein kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.-" evidence="8"/>
    <dbReference type="EMBL" id="LUGH01000044">
        <property type="protein sequence ID" value="OBZ90549.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NNU2"/>
    <dbReference type="FunCoup" id="A0A1C7NNU2">
        <property type="interactions" value="547"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NNU2"/>
    <dbReference type="InParanoid" id="A0A1C7NNU2"/>
    <dbReference type="OrthoDB" id="241648at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004740">
        <property type="term" value="F:pyruvate dehydrogenase (acetyl-transferring) kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010906">
        <property type="term" value="P:regulation of glucose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd16929">
        <property type="entry name" value="HATPase_PDK-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.140.20">
        <property type="entry name" value="Alpha-ketoacid/pyruvate dehydrogenase kinase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="entry name" value="Histidine kinase-like ATPase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036784">
        <property type="entry name" value="AK/P_DHK_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018955">
        <property type="entry name" value="BCDHK/PDK_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039028">
        <property type="entry name" value="BCKD/PDK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11947:SF3">
        <property type="entry name" value="[PYRUVATE DEHYDROGENASE (ACETYL-TRANSFERRING)] KINASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11947">
        <property type="entry name" value="PYRUVATE DEHYDROGENASE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10436">
        <property type="entry name" value="BCDHK_Adom3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69012">
        <property type="entry name" value="alpha-ketoacid dehydrogenase kinase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 8 10" id="KW-0418">Kinase</keyword>
    <keyword evidence="6 8" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="3 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Histidine kinase" evidence="9">
        <location>
            <begin position="258"/>
            <end position="388"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00048201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU366032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OBZ90549.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="396" mass="45224" checksum="1DD702A650657BAE" modified="2016-11-30" version="1">MVMFGQKPAPATLFKASQFLHEELPIRLAHRVKELDELPKSLGEMPSIIKVKNWYAQSFQELIELPHPELTPELKATFRSASRHAPPLPESTPNLAIPLLKPANKYFPSVSIGHRYYNNIENIECPPALVSYTDTFVRAIETVKRRHDPVVTTMAQGIMEYKQHRKASMIDSDVQQFLDRFYMSRIGIRMLIGQHSALYRGPFMRNYVGVICTKTNIKEICQDAIANARFICEDHYGLFKAPEVQMFYPGDIEFMYVPSHLNHMVFELLKNSLRAVVERFGSDYEDEYPPIKLIIAHGKEDITIKISDEGGGLPRSGIPVVWTYMYTTAKAQELEPEFNKSEFKAPMAGFGYGLPISRLYARYFGGDLKLISMEGYGTDAYLHLNRLSNSDEPLIM</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NP03</accession>
    <name>A0A1C7NP03_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_01114</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000032">
        <property type="protein sequence ID" value="OBZ90845.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NP03"/>
    <dbReference type="InParanoid" id="A0A1C7NP03"/>
    <dbReference type="OrthoDB" id="10646053at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="74"/>
            <end position="99"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ90845.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="183" mass="20569" checksum="2E0EB82D29E984E9" modified="2016-11-30" version="1">MSIPTIEFLVHPPSPKAVSQLNITLPPVSTLLQEVNHLGPSLHMPSPTLSFASYSSSASSPLISPLLSPLLLSDSEEQENPIKRKRGRPPNNRREKKEQFTFTTPTVCDSAHAQTTVAEEHTLENFVVLQWQEKNNSDVSSISTPKRRRGRKPKTQLAGNLCFVWRDPTIHHYTNKKIKEKSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NPD8</accession>
    <name>A0A1C7NPD8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="10">COBW domain-containing protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">Cbwd1_0</name>
        <name evidence="10" type="ORF">A0J61_01101</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>GTP + H2O = GDP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:19669"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58189"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="7">
            <dbReference type="Rhea" id="RHEA:19670"/>
        </physiologicalReaction>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000031">
        <property type="protein sequence ID" value="OBZ90868.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NPD8"/>
    <dbReference type="FunCoup" id="A0A1C7NPD8">
        <property type="interactions" value="323"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NPD8"/>
    <dbReference type="InParanoid" id="A0A1C7NPD8"/>
    <dbReference type="OrthoDB" id="258627at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008047">
        <property type="term" value="F:enzyme activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140827">
        <property type="term" value="F:zinc chaperone activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034224">
        <property type="term" value="P:cellular response to zinc ion starvation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051604">
        <property type="term" value="P:protein maturation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd03112">
        <property type="entry name" value="CobW-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1220.10">
        <property type="entry name" value="CobW-like, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036627">
        <property type="entry name" value="CobW-likC_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011629">
        <property type="entry name" value="CobW-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003495">
        <property type="entry name" value="CobW/HypB/UreG_nucleotide-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051316">
        <property type="entry name" value="Zinc-reg_GTPase_activator"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13748">
        <property type="entry name" value="COBW-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13748:SF31">
        <property type="entry name" value="ZINC-REGULATED GTPASE METALLOPROTEIN ACTIVATOR 1A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02492">
        <property type="entry name" value="cobW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07683">
        <property type="entry name" value="CobW_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90002">
        <property type="entry name" value="Hypothetical protein YjiA, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0143">Chaperone</keyword>
    <keyword evidence="4" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="CobW/HypB/UreG nucleotide-binding" evidence="8">
        <location>
            <begin position="32"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="domain" description="CobW C-terminal" evidence="9">
        <location>
            <begin position="267"/>
            <end position="376"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00034320"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00049117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF07683"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OBZ90868.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="382" mass="42846" checksum="812D28423D11DE88" modified="2016-11-30" version="1">MADEFEDIPDLVPAVAPIQSTFEAEQEHKKIPVTIVTGFLGSGKTTLLNYILTEKHDKKIAVILNEFGESSDIEKSLSINQDGNLYEEWLELRNGCLCCSTKDVGVKAIENLMEKKGKFDYILLETSGLADPGPIASMFWLDDGLGSEIYLDGIVTLVDAKYIRDHINEKREDVMINEALKQIAIADRIVINKKDLLSEDELKTLQADLASVNTVADMLVTERSRIPLDYVLNINAYDVNNADGLVQQTKKIEEHGNNHAHEISHEIQTICIQFNSQLDSLEPLERWIQELLWEKHLLGIESEDNIVVLRLKGIVYPPKNHTDTSPKKRLVIQGVQDLYDIQEGLTEHASDAMTSKIVLIGKNLDRTKIARSFATAVGVDIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NPE3</accession>
    <name>A0A1C7NPE3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Nitrogen assimilation transcription factor nirA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">nirA_1</name>
        <name evidence="9" type="ORF">A0J61_00968</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000026">
        <property type="protein sequence ID" value="OBZ90992.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NPE3"/>
    <dbReference type="STRING" id="101091.A0A1C7NPE3"/>
    <dbReference type="InParanoid" id="A0A1C7NPE3"/>
    <dbReference type="OrthoDB" id="4161332at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051615">
        <property type="entry name" value="Transcr_Regulatory_Elem"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31313">
        <property type="entry name" value="TY1 ENHANCER ACTIVATOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31313:SF81">
        <property type="entry name" value="TY1 ENHANCER ACTIVATOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Xylanolytic transcriptional activator regulatory" evidence="8">
        <location>
            <begin position="190"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="470"/>
            <end position="491"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="513"/>
            <end position="532"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="521"/>
            <end position="532"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OBZ90992.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="554" mass="63242" checksum="A8E9463CFE7168CF" modified="2016-11-30" version="1">MQCKVRRKHCSFTRTDLQSNDEHSIPENSISDREKLADISSRIDKLSMTSPGQGREGRWLVDINLLFHGDNTIKNRKNTSAVHDTIDTDMINLFFEHKYNIFPIIQKSIFYRLLEHQDPLITPCLLYSIYCHGAQYKNMAKADDYYQKAEILVRESLRRPSIATVISLSLLSMYESNGSSTGSGINNGLSRIYRDMACRLCYDLKLHKRCSSNNAVVTLDEMELRKRAYWVCYCMDKINSMLTGKPCLLSLRDADIDMPTVLSTGDPNELDINRCFLEHIRLMKISEQALLMDIPEHQAGTARLPENEQQVLTLDHYLSIWFDQLPPILKHLPLQEGGLMEPFVAHIRLVYCFVAIFVLQPITFISSSCSSDSKHIQQRCRTVANEITCLGYAMVHQPNTILSFTLLAQVLMAATRVHIMDCADENLALAKEARFMFQQSLRALKGILQFRIVPYIFEFTATVEKALRDADTGDSCTRNSSPKVHMLSPIYPKPTSAEQDRLLSEFSQNRFYQPIPPPPLSEESSVDPSSSRSVYDLEHAFSSTGIQSWQEDRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NPZ6</accession>
    <name>A0A1C7NPZ6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Putative transporter C11D3.18C</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">A0J61_01415</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000045">
        <property type="protein sequence ID" value="OBZ90516.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NPZ6"/>
    <dbReference type="STRING" id="101091.A0A1C7NPZ6"/>
    <dbReference type="InParanoid" id="A0A1C7NPZ6"/>
    <dbReference type="OrthoDB" id="2985014at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791">
        <property type="entry name" value="PERMEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791:SF36">
        <property type="entry name" value="TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_6G08340)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="20"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="53"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="123"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="159"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="186"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="213"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="242"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="121"/>
            <end position="282"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OBZ90516.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="282" mass="31219" checksum="746DB8C277AEA971" modified="2016-11-30" version="1">MYLLSKFYKPEEFGVRVGLLIAMATLSGLVSGPLAYAMSWFDGKNGLSDWQYLYIFEGVPTIVLSFVSYFFLFDDLQEVSWLSNEQKQLQLHRMSTSQHEDFKDKNTIDFSTFKKVFEDWKTWAFSFVCLLNSINIISISVFAPSLIDGFGFSHLTSQLLTAPPFAVATIAVLIGGYLSGRYGKRSLLLSIGSLIIAIGYLCLLLVDDRWALYGALFVIPAGAGIQAASAIGWSAINYSDLTVRAIAVAFVLMVGNIGSIIAAYLFNTKDAPRYGKREKAKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NQ38</accession>
    <name>A0A1C7NQ38_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="14">General negative regulator of transcription subunit 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">not3_1</name>
        <name evidence="14" type="ORF">A0J61_00743</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the CNOT2/3/5 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000018">
        <property type="protein sequence ID" value="OBZ91217.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NQ38"/>
    <dbReference type="FunCoup" id="A0A1C7NQ38">
        <property type="interactions" value="604"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NQ38"/>
    <dbReference type="InParanoid" id="A0A1C7NQ38"/>
    <dbReference type="OrthoDB" id="293823at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030015">
        <property type="term" value="C:CCR4-NOT core complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000289">
        <property type="term" value="P:nuclear-transcribed mRNA poly(A) tail shortening"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.30.1020:FF:000006">
        <property type="entry name" value="CCR4-NOT transcription complex, subunit 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.1020">
        <property type="entry name" value="CCR4-NOT complex subunit 2/3/5, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038635">
        <property type="entry name" value="CCR4-NOT_su2/3/5_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012270">
        <property type="entry name" value="CCR4-NOT_su3/5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040168">
        <property type="entry name" value="Not2/3/5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007282">
        <property type="entry name" value="NOT2/3/5_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007207">
        <property type="entry name" value="Not_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23326">
        <property type="entry name" value="CCR4 NOT-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04153">
        <property type="entry name" value="NOT2_3_5_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04065">
        <property type="entry name" value="Not3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005290">
        <property type="entry name" value="NOT_su_3_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0678">Repressor</keyword>
    <keyword evidence="8" id="KW-0804">Transcription</keyword>
    <keyword evidence="7" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="CCR4-Not complex component Not N-terminal" evidence="12">
        <location>
            <begin position="3"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="domain" description="NOT2/NOT3/NOT5 C-terminal" evidence="13">
        <location>
            <begin position="385"/>
            <end position="506"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="146"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="253"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="10">
        <location>
            <begin position="3"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="158"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="254"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="268"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="301"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="311"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="341"/>
            <end position="351"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF04065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF04153"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="OBZ91217.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="529" mass="63155" checksum="9B6027868D845332" modified="2016-11-30" version="1">MSMKKLQAEIDRLLKKVSEGVETFEAIFDKIHYTNNANQKDKYEQDLKKEIKKLQRLRDQIKTWLANNDIKDKRALLENRKLIEAQMERFKQVEKEMKTKAYSKEGLLQRERLDPKDKEKADCCDFLTNAVDELSRQIETVEFEMEQLEGTGSKRNNKKQDHQRTERLNELEHSNERRKWHINRLELILRLLENDHLDAERVSEFKDVIQYYVECNQEPDFEEDEGLYDDLDLEKEEELYAIRTDEYHAKIDSDHEEAEEEEEEENQPQKQSEKSTPLTSPKKVSKEDTQPMVKTPKPESINKQPSSNFSTTTTTTTTTTTTTTTTTNVSAWNEPPKIVDQSKTVPSSHSDYQLPSSLADLAPSFESVKNRRHDIQYTHQMLDASLQHVPDLIDSERPKVYQPRNPFNTPNYYPQQPLLIFDNPMLFDKFDMDTLFFIFYYQQGTYQQYLAAKELKKQSWRFHKKYLTWFQRHEEPKIITEDYEQGTYIYFDYEGAWCQRKKTEFRQVFFMYQLYLLMLTFQIDLIIVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NRG1</accession>
    <name>A0A1C7NRG1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_00266</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000005">
        <property type="protein sequence ID" value="OBZ91693.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NRG1"/>
    <dbReference type="STRING" id="101091.A0A1C7NRG1"/>
    <dbReference type="InParanoid" id="A0A1C7NRG1"/>
    <dbReference type="OrthoDB" id="5673at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1410.10">
        <property type="entry name" value="Chorismate lyase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028978">
        <property type="entry name" value="Chorismate_lyase_/UTRA_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64288">
        <property type="entry name" value="Chorismate lyase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ91693.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="193" mass="22021" checksum="E830EA42DE624C0F" modified="2016-11-30" version="1">MTKALPDPVDTEHYERIPFQFTEELSSKNVFVRLPESFSPLERILLQSAGNLQRILSAYYNVPSQVEIVKNEAVPSADSTLMQFDRKIVMYFGEKLVYEAESILAVKDSSVLELIEKHKFGLGQIFGHTHRSPNFVLHAIGRHGNEPGASFWRDYTLTIPDVLDCFIRETFVEGLFEEHSGGKHEGTIWYDAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NRS4</accession>
    <name>A0A1C7NRS4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="18">Phospholipid-transporting ATPase</fullName>
            <ecNumber evidence="18">7.6.2.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="22" type="primary">DNF1_0</name>
        <name evidence="22" type="ORF">A0J61_00170</name>
    </gene>
    <organism evidence="22 23">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="22 23" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="22 23">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="13 18">
            <text>ATP + H2O + phospholipidSide 1 = ADP + phosphate + phospholipidSide 2.</text>
            <dbReference type="EC" id="7.6.2.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>a 1,2-diacyl-sn-glycero-3-phosphoethanolamine(out) + ATP + H2O = a 1,2-diacyl-sn-glycero-3-phosphoethanolamine(in) + ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:66132"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:64612"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="14">
            <dbReference type="Rhea" id="RHEA:66133"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="17">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="18">Membrane</location>
            <topology evidence="18">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 18">Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="22">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="7.6.2.1" evidence="18"/>
    <dbReference type="EMBL" id="LUGH01000003">
        <property type="protein sequence ID" value="OBZ91812.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="FunCoup" id="A0A1C7NRS4">
        <property type="interactions" value="83"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NRS4"/>
    <dbReference type="InParanoid" id="A0A1C7NRS4"/>
    <dbReference type="OrthoDB" id="377733at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140326">
        <property type="term" value="F:ATPase-coupled intramembrane lipid transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045332">
        <property type="term" value="P:phospholipid translocation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02073">
        <property type="entry name" value="P-type_ATPase_APLT_Dnf-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.1110.10:FF:000087">
        <property type="entry name" value="Phospholipid-transporting ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1000:FF:000014">
        <property type="entry name" value="Phospholipid-transporting ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1000:FF:000001">
        <property type="entry name" value="Phospholipid-transporting ATPase IC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.150.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023299">
        <property type="entry name" value="ATPase_P-typ_cyto_dom_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018303">
        <property type="entry name" value="ATPase_P-typ_P_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023298">
        <property type="entry name" value="ATPase_P-typ_TM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008250">
        <property type="entry name" value="ATPase_P-typ_transduc_dom_A_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006539">
        <property type="entry name" value="P-type_ATPase_IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032631">
        <property type="entry name" value="P-type_ATPase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001757">
        <property type="entry name" value="P_typ_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032630">
        <property type="entry name" value="P_typ_ATPase_c"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044492">
        <property type="entry name" value="P_typ_ATPase_HD_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01652">
        <property type="entry name" value="ATPase-Plipid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01494">
        <property type="entry name" value="ATPase_P-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24092:SF180">
        <property type="entry name" value="PHOSPHOLIPID-TRANSPORTING ATPASE DNF1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24092">
        <property type="entry name" value="PROBABLE PHOSPHOLIPID-TRANSPORTING ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13246">
        <property type="entry name" value="Cation_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16212">
        <property type="entry name" value="PhoLip_ATPase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16209">
        <property type="entry name" value="PhoLip_ATPase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00119">
        <property type="entry name" value="CATATPASE"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG00002">
        <property type="entry name" value="C1.7:_P-type_atpase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00003">
        <property type="entry name" value="Haloacid_Dehalogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00027">
        <property type="entry name" value="p-type_atpase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81653">
        <property type="entry name" value="Calcium ATPase, transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81665">
        <property type="entry name" value="Calcium ATPase, transmembrane domain M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81660">
        <property type="entry name" value="Metal cation-transporting ATPase, ATP-binding domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00154">
        <property type="entry name" value="ATPASE_E1_E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 16 18" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9 17 18" id="KW-0460">Magnesium</keyword>
    <keyword evidence="12 18" id="KW-0472">Membrane</keyword>
    <keyword evidence="6 17" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 16 18" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="23" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10 18" id="KW-1278">Translocase</keyword>
    <keyword evidence="5 18" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="11 18" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="88"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="111"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="477"/>
            <end position="500"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="520"/>
            <end position="543"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="1082"/>
            <end position="1101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="1113"/>
            <end position="1134"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="1164"/>
            <end position="1184"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="1204"/>
            <end position="1225"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="1232"/>
            <end position="1252"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="1267"/>
            <end position="1287"/>
        </location>
    </feature>
    <feature type="domain" description="P-type ATPase N-terminal" evidence="20">
        <location>
            <begin position="58"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="domain" description="P-type ATPase C-terminal" evidence="21">
        <location>
            <begin position="1050"/>
            <end position="1296"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="19">
        <location>
            <begin position="1315"/>
            <end position="1361"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="19">
        <location>
            <begin position="1315"/>
            <end position="1334"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="19">
        <location>
            <begin position="1335"/>
            <end position="1346"/>
        </location>
    </feature>
    <feature type="active site" description="4-aspartylphosphate intermediate" evidence="15">
        <location>
            <position position="591"/>
        </location>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="591"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="591"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="592"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="593"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="593"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="720"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="761"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="785"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="829"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="909"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="910"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="911"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="998"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="1004"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="1024"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="1027"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="1028"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="1028"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00034036"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00049128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PIRSR" id="PIRSR606539-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PIRSR" id="PIRSR606539-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="PIRSR" id="PIRSR606539-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="RuleBase" id="RU362033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="Pfam" id="PF16209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="21">
        <source>
            <dbReference type="Pfam" id="PF16212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="EMBL" id="OBZ91812.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="1361" mass="154593" checksum="53F6D3BA1BFB0712" modified="2016-11-30" version="1">MSKRLGWKALFSKRSSSDEEADRIHRTESTSSYMQRRKIYVNMKPPASDYDEKGRLIGHSYVPNRIRTAKYTPLSFIPKNLFEQFRNVANLYFLFLVILQCFPIFGVVEPAVSALPIIAILIITGIKDAIEDTKRNKSDQRVNRARTLTLIHWKNVNLPEQEKGRFHTVHVLLGFFCMLAGVDNRFTHTYRMAFVRKPSQPVELDFDRPLNQVDENTSEENQSTSDNQPSSSTFYNKVRLRSGTFRTDLNGFFKSSSAAGKQIYRPGIIPHSVLHRTTTASIRRRSSSVHINTDCSALSPDEPPSPECKVGWQYVQWQDVQVGDYVMIQNDEEVPADIIILSTSEKDNLCYVETQNLDGETNLKVRQGLKATGELRTVHDCERAYFYFESEPPNVNLYQYNGVMRWDIEQPDGESTVTHQKTEAVTYNNLLLRGCVLRNTRWAIGVIVYTGAETKIMLNSGSTPSKRSKMSKATNPYVVANFCILAILCIISSVLSSVNFNASGSSRYFDYGIEGTSASYLGFITFWVTLILYQNIVPISLYISVEIVKTLVAYFVYADLDMYHEPTDAPCIPKTWNICDDLGQIEYIFSDKTGTLTQNVMESRKATINGISYGMGKTEASAGADIRQGSDISDMKQDDLDHAREIMYSKQATLFENKYIGPNPTLIDPAIYNDLERDDLHAASVAHFFSALALCHTALADRPDRTDRHHIEYKAQSPDESALVASARDLGFVFLGRESNVLTVEVMGRKKKYDLLNVLEFNSNRKRMSVIVKPHESDRIVLLCKGADSVIYDRLCTDFGDQHELDQAQARLREITLEHLEGFANEGLRTLCLAYRFISQREYRSWNRRFQEASAAIYSREDRIEEICEEIEVNMLLMGGTAIEDRLQDGVPETIAELSRSGIKLWVLTGDKTETAINIGFSCNLITLDMELVVVKAEDRESTASELERALERVDRVGDTKRCALVIDGITLKFALEPQTETKLLDLGTRCASVVCCRVSPKQKAQVVRLVKKGLRVMTLAIGDGANDVSMIQEANVGVGISGVEGRQAVMASDYAIAQFRFLQKLLLVHGRWSYLRIAEMVMGFFFKNIVWTFVLFWYQLFCQFNGSMMFEYVLVTLYNVVFTSLPIIFMGIWDQDLNAKVSSLYPELYRMGLRNDKFKTWRFYLTVLDGIYQSSVCFFFPYMLLLGGPVDPEGRDQNGMYSFGTIVSSIVVIVANLFVVVSLYSFTWIQILVISLSILVYYVIVCIYAQFNTFLFAGQHSLFGTGNYWMTLILTIVACFLPRVVAKHYRHQYRPYDNDIIREQELVLHQGRSSQIHNDSHGSSLETKAITQTSKEEPAQERPADQVDLDPEIVHRRPSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NSA5</accession>
    <name>A0A1C7NSA5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Leucine-rich repeat-containing protein 16A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">Lrrc16a</name>
        <name evidence="3" type="ORF">A0J61_01799</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000061">
        <property type="protein sequence ID" value="OBZ90144.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NSA5"/>
    <dbReference type="InParanoid" id="A0A1C7NSA5"/>
    <dbReference type="OrthoDB" id="120976at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016477">
        <property type="term" value="P:cell migration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034315">
        <property type="term" value="P:regulation of Arp2/3 complex-mediated actin nucleation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00821">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057334">
        <property type="entry name" value="PH_2nd_LRR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001849">
        <property type="entry name" value="PH_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051279">
        <property type="entry name" value="PP1-Reg/Actin-Interact_Protein"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24112:SF66">
        <property type="entry name" value="LEUCINE-RICH REPEAT, ISOFORM F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24112">
        <property type="entry name" value="LEUCINE-RICH REPEAT, ISOFORM F-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00169">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25353">
        <property type="entry name" value="PH_2nd_LRR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00368">
        <property type="entry name" value="LRR_RI"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SMART" id="SM00233">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50003">
        <property type="entry name" value="PH_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PH" evidence="2">
        <location>
            <begin position="197"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="12"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="60"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1157"/>
            <end position="1188"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1250"/>
            <end position="1272"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="25"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="61"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1166"/>
            <end position="1188"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1250"/>
            <end position="1267"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ90144.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="1381" mass="156053" checksum="CA846E1A155219F0" modified="2016-11-30" version="1">MANINYYSSRAYSQSSNSIHKDRTQSISAESGMSSDHSVSNLRNPPYHFPMPSYSNLSTYSVTSPTSEHSHSSTSYTHLNTSDHDGQYFSSTVAPISPSTSINERHYFNAQPSLRPSNHSIASRSPPSSYYYYGQDSVVYGTELVADGEAGTFGGHRSSISTRTTVSSTTSLDTFPPTEEAKQKANAALQANQSSFKVIYAGDIVYRPDKGILNKSKRSYFVLTNTHLLVYKSSQKARSEINMFEHHHDDFHNEIVHDRKSNKVFDKDKIFLKLSNIYAVHTSATTACLFRIEYFHSQSGQALSHSLMADTEKERRQWVQALRKSVRIHHPQINGISSAERSTVLERLGKQNDTFSNTDEVKVFKVVFKEKRYKVGSDVAKEVFLPIFLVIGKFSFYFLPVSVLDDEYLKMVERDRFGFLSLLSIRYENTDDTVILEVKQVSKSNRQLVFASTFCENIIQYLYRGVDSLVPGAANQLYTENVPSRIKQTQVIQIQILNELDDELVDSNDEEVKRFSITLQAYCAAMNMNKSRFNFMLTGPPKAKTFTLLPPKEIGQTPPYYEKYELLAIFRTLQANNVFVEVCLANCSLHALETWKIQHTHGWVYDEHHPLKDNNLLSNEIYSVLTKLRLLRKLDLTNCSIGKPSPDSLVQQSSAISTIGIVMRSGKTHVSRICLGKNTIYESDLEKLIQGIREHKKSIKELYLNECGLSKDMIEQVLRTLFAKTPDQLISLDLSISKRPSPPLIDSSLIEKLIPTFKRLEYLCMRGFGLXXTDYYRFLLESGHLRELDLGNSCMNADSVARVCKWILSPSFQSIEALHLGGCGLNGKHVSDILKSISQSGNRTLHLNLENNPIMKEVMHLPKLHTVILQGEGPKSISLARVEWDDSTLCEFIDCLRDNQTITHLDLSDITMRDTNSISDDTIRMLTSLFERNTSITELEISMTSGQTKPMISDAITRAIQGLRHNNYLQHLDISGLNIGDAGAFTLSRVLKTNRTLQSIIIDENNISIEGYRSLLKTIEESAKQVINFPTPRIDVRNQLRYLNFRSEELIISENEARFFLIHTTASDKKRLKRHELEVLIQERKACEFALNNLEGVIHALTLVVRKNMREYQEQTFRNMEFQMQAQNAAQELAIAQVRLQNRSAAVLNVAHGGLVGGPLRPRHPSSSAASTTSSATNSVSESLSRSASRSQTYYPRSSYCRSTVSTDFPTNTYPFSSTYSEQRGYMAAFPAPSAPISSISPFIRGGNVQRQTNGPYDQPTPATSKPHSHEYTSTHFPFTPSAEYIDSYFRELGIEPTNDYLVSHPHSNVIDSFSQDDPGFISDFGNPEDFVQGGLIDAHFTEHTHHLKAYPTSNSTSDWNDEETLKKFNHALYLPPDERV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NSN7</accession>
    <name>A0A1C7NSN7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">HMG-box protein STE11</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">STE11_1</name>
        <name evidence="6" type="ORF">A0J61_00265</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000005">
        <property type="protein sequence ID" value="OBZ91696.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NSN7"/>
    <dbReference type="STRING" id="101091.A0A1C7NSN7"/>
    <dbReference type="InParanoid" id="A0A1C7NSN7"/>
    <dbReference type="OrthoDB" id="6247875at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01389">
        <property type="entry name" value="HMG-box_ROX1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.30.10">
        <property type="entry name" value="High mobility group box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009071">
        <property type="entry name" value="HMG_box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036910">
        <property type="entry name" value="HMG_box_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051356">
        <property type="entry name" value="SOX/SOX-like_TF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45789">
        <property type="entry name" value="FI18025P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45789:SF2">
        <property type="entry name" value="FI18025P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00505">
        <property type="entry name" value="HMG_box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00398">
        <property type="entry name" value="HMG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47095">
        <property type="entry name" value="HMG-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50118">
        <property type="entry name" value="HMG_BOX_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2 3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HMG box" evidence="5">
        <location>
            <begin position="47"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="HMG box" evidence="3">
        <location>
            <begin position="47"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="113"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="121"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="146"/>
            <end position="157"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OBZ91696.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="366" mass="42114" checksum="E381886CD3805ED9" modified="2016-11-30" version="1">MLDHNELSKHFNESQKQDVIHLYETDLQTPIKRIRKKRVRAIKPDHIPRPVNSFISFRTEKQALIRKFCPTANHREISKITARWWRTAEAKDKEVFIKKAATAKVEHSKKYPDYVFSPKSKNPRKPRKSSSRKPKRTLCTDMDPPANSTSTQLVRASNESAPPFGDYAVFQDKETYNDRIVYPGAYQIWPYGVNAQFSGFSNQYYDLLPSHNNNYEIPDTAIYPSYMPYDDYAAQLSYHPYSFNNLISNLALQNYEVDDCNNELLYHESDNTPHSQILNTPSLDHVKSPASSYCQQGWGVDDPCSMLASLNPTPFKMIEDEIQDTKSAQACVFTEQLIKPLDASHMSCELQRTLDDPAFSSSLHLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NWK1</accession>
    <name>A0A1C7NWK1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_00174</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000003">
        <property type="protein sequence ID" value="OBZ91814.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NWK1"/>
    <dbReference type="InParanoid" id="A0A1C7NWK1"/>
    <dbReference type="OrthoDB" id="2250046at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015946">
        <property type="entry name" value="KH_dom-like_a/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023799">
        <property type="entry name" value="RbfA_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89919">
        <property type="entry name" value="Ribosome-binding factor A, RbfA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ91814.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="228" mass="26456" checksum="FFB58B1E4464FFF6" modified="2016-11-30" version="1">MSIHRFVLSTPKVSPFTSQRLFSTTAKAFKKQPKEPRYSVQNQQVLDDYMIPGPALRFFKTKRTKKPQETTYPLSEHGLENMYTAPARSIRYNEFDSAPTVVQERLAERIHRAITTMYSVETLPTQWITPQHVLIRAVKVSRNLRKCRVLYEALSDKKKERGHTHRSLSVYTPLLNTHRSLSVYTPLLNTLIHSHANIKHPLSIKFIPDTQTKELDDIFKQIVSEQNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-06-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7LJJ7</accession>
    <name>A0A1C7LJJ7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_11962</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01002776">
        <property type="protein sequence ID" value="OBZ63922.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7LJJ7"/>
    <dbReference type="InParanoid" id="A0A1C7LJJ7"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="167"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ63922.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="167" mass="19284" checksum="50AB52D4F63CFAB2" modified="2016-11-30" version="1" fragment="single">MKEDFVLNLIEVQDGNPVIQGEDFDFLDNDDAQDWIEINGAYDFEEGQLDITSVLKWNSNDLSLTRKRKRARSAILTKRAIRKRKQKNREMAQNCKKVTEYFQPYKKCTVEISEDEEQSEESEEEQDVESSMIRAAIGKVSLTLVPVLNAKSDIAKIVSYMILRLMA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MUF9</accession>
    <name>A0A1C7MUF9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_11460</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01002058">
        <property type="protein sequence ID" value="OBZ80491.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MUF9"/>
    <dbReference type="InParanoid" id="A0A1C7MUF9"/>
    <dbReference type="OrthoDB" id="2290247at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="30"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="55"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="71"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="145"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ80491.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="197" mass="22217" checksum="22436D518DB03686" modified="2016-11-30" version="1" fragment="single">QSPNLIESTSRLTMRKYPSAHDIRKAAKLQQDSIQQVSTERMPTLHKVQPRPPNMTRSRSASTSSPKHKLLPPPVMSPPLLPKQTIRHPLPYDDNNDDDDDVPLGFLQSPISKPSSLLSDQDDEDDNDLVPIAALTASPHSPLTNKDKDYQTAADKYKERVKERLHLDEEEKKGNDDDDIPISLALLSFKDRIGRKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MUI4</accession>
    <name>A0A1C7MUI4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_11469</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01002069">
        <property type="protein sequence ID" value="OBZ80482.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MUI4"/>
    <dbReference type="InParanoid" id="A0A1C7MUI4"/>
    <dbReference type="OrthoDB" id="2279551at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="339"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ80482.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="339" mass="38597" checksum="989B8176AE655D9A" modified="2016-11-30" version="1" fragment="single">MGSKNRHGLIHKSHYSPWLAQSIDILRSKVGHPFRTDSYFGNNLLGNTYLYGHKTEKFGITPIPSHIKIDHLMKPYDPLTYFKPDQSIESNTINTSNSQSPSKKFLEEQTKSHLARFTKSRISEERIFELSTLPIVKLPNIYYASHQFIYRYLSKCQGTKYAVTAVHTPQEKALFSSMLSDSTENAKYVYLKSSNGSINFGLMAAAWSKLCSSSNYIYYKTPEHLYSYYNILEDRKKYRDTVAHNIDASRSIRLLGQCKRRYVSSEQAKKYRRLEPSLLTCTSIVSTSTTEIAKEAPVNIAPRPSAIDPPIEIIDPSVITRGSLENEVLNIADNQTNEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MUW9</accession>
    <name>A0A1C7MUW9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Sorbitol dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">SORD</name>
        <name evidence="10" type="ORF">A0J61_11383</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 7">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the zinc-containing alcohol dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001974">
        <property type="protein sequence ID" value="OBZ80568.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MUW9"/>
    <dbReference type="STRING" id="101091.A0A1C7MUW9"/>
    <dbReference type="InParanoid" id="A0A1C7MUW9"/>
    <dbReference type="OrthoDB" id="2148442at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046526">
        <property type="term" value="F:D-xylulose reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003939">
        <property type="term" value="F:L-iditol 2-dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006062">
        <property type="term" value="P:sorbitol catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05285">
        <property type="entry name" value="sorbitol_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000068">
        <property type="entry name" value="Sorbitol dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002328">
        <property type="entry name" value="ADH_Zn_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045306">
        <property type="entry name" value="SDH-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43161">
        <property type="entry name" value="SORBITOL DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43161:SF9">
        <property type="entry name" value="SORBITOL DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00059">
        <property type="entry name" value="ADH_ZINC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0520">NAD</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Alcohol dehydrogenase-like N-terminal" evidence="9">
        <location>
            <begin position="1"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="domain" description="Alcohol dehydrogenase-like C-terminal" evidence="8">
        <location>
            <begin position="118"/>
            <end position="256"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU361277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00107"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF08240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OBZ80568.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="296" mass="31530" checksum="7F497641238BDC67" modified="2016-11-30" version="1">MVLGHESAGIVASVGEGVNHLKVGDPVALEPGVPCRNCEMCKNGKYNLCPDMVFAATPPYDGTLCQFYKHAADFCYKLPESVSLEEGALIEPLSVGIHASRRGEIKLGDRVFVFGAGPVGLLTAAAAKAAGAAHVTIADISESRLSFAKSYIADATIHLTNKPPQGEKDTNAFARQEADKILEHTLPANVVFDCTGVEVCVQMSVYLVKNSGRIVLVGMGASVQSISVADVSAREVDVRGVMRYCNTYPTAVEMLASGKIDLKSLVTHRYTFQDSLEAFKHVAEGRAGTIKVVITN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-06-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MV47</accession>
    <name>A0A1C7MV47_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_11238</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001814">
        <property type="protein sequence ID" value="OBZ80713.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MV47"/>
    <dbReference type="InParanoid" id="A0A1C7MV47"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ80713.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="102" mass="12104" checksum="74286DAB9DA2CB9E" modified="2016-11-30" version="1">MLYEGLRTSEVLYKETTEMERASRENDYQLQLAQDNERLVVVKERWEKKYQFKVNQTQAQLQHQQRDLKITEAHAQAEYVKMLLSVGETPEQAAKAVQEFIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MV89</accession>
    <name>A0A1C7MV89_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="2">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">A0J61_11199</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="2"/>
    <dbReference type="EMBL" id="LUGH01001768">
        <property type="protein sequence ID" value="OBZ80752.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MV89"/>
    <dbReference type="STRING" id="101091.A0A1C7MV89"/>
    <dbReference type="InParanoid" id="A0A1C7MV89"/>
    <dbReference type="OrthoDB" id="381190at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005694">
        <property type="term" value="C:chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000077">
        <property type="term" value="P:DNA damage checkpoint signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000723">
        <property type="term" value="P:telomere maintenance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056802">
        <property type="entry name" value="ATR-like_M-HEAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050517">
        <property type="entry name" value="DDR_Repair_Kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003151">
        <property type="entry name" value="PIK-rel_kinase_FAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014009">
        <property type="entry name" value="PIK_FAT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11139">
        <property type="entry name" value="ATAXIA TELANGIECTASIA MUTATED ATM -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11139:SF69">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE ATR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02259">
        <property type="entry name" value="FAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25030">
        <property type="entry name" value="M-HEAT_ATR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51189">
        <property type="entry name" value="FAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0227">DNA damage</keyword>
    <keyword evidence="7" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="FAT" evidence="10">
        <location>
            <begin position="339"/>
            <end position="601"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="11">
        <location>
            <position position="601"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="OBZ80752.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="601" mass="68909" checksum="B44CA6C5076340AB" modified="2016-11-30" version="1" fragment="single">MSQMQYRHNLNLILSNLQEADDVPVQIALDKLEVYLNDHTVQEYQLSQVYSRLLYIIHKYANNKPISLKAAKCLGKLGALDPGLISVPTIDDTVFVINDFTRVDEVSDFVCELITNHLYPAYNAASSDTAIRRCIEYAIKPLLDAAGLQPSDLTISAERHQAKTHGFQKMPSAIQQFIAPFFVAAYEASWDTRTDDYPIFLKAQGFDNWIQAWYLRMASNSVGTAQKIFQALVPTVKSNLQDITQHLIPYLVMHSLLSGTGDDTRGVINELIDVIHANADSRIDHDNSATAWYRRALQVAVETTEYCRKWLNRVGRHDKEKESHVKRVNMFLQEMPRKEMGVAAFYAKAYPQSLMQFETYVKEKGASNIDGDLLDYLRQIYIQLEDSVDLKALMEMYTNVGGSYTNALKLDERISIYESLGRWDEVEVLYKGKTREEGASLPAYTGYLDCLKKTGSYDKMIYQTQVLSNQMPKWLPFINSYRIDASWRLKDWKSLEESSSLPMNRDIPALIGCIINEMHKNNCIEAAQLMDEARIKVIEQLTMSQSKSYRKSYPLLFNLQLIEELEESQVTSETPERAKHLENLEARWKKTFGNIVPHTQH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MVI3</accession>
    <name>A0A1C7MVI3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Reverse transcriptase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_11183</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001755">
        <property type="protein sequence ID" value="OBZ80768.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MVI3"/>
    <dbReference type="STRING" id="101091.A0A1C7MVI3"/>
    <dbReference type="InParanoid" id="A0A1C7MVI3"/>
    <dbReference type="OrthoDB" id="5598377at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000477">
        <property type="entry name" value="RT_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19446">
        <property type="entry name" value="REVERSE TRANSCRIPTASES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00078">
        <property type="entry name" value="RVT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Reverse transcriptase" evidence="1">
        <location>
            <begin position="318"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="423"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ80768.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="423" mass="48234" checksum="BBD3CDC4CFC63293" modified="2016-11-30" version="1" fragment="single">FQCAHAQLAVCWRTATTQLSFNLRCSDRLLSLRFRLLTKSDDTPSATANGHGFWKAQPRIGQDSEFQAKLNFHLSATIRELNSTLPAWHKWERIKLVAAKTVRAHSRRQAFSVARAESLLQRKWAKIESNLMNNLSLHPCLPPQLHIQYHVETLSLKAGIRWREQRELSAGYLKRTASARLTKTTIPPRFHPTFDRVCVFKDEMLDAAFVFYDNLLAPNPIGLNAKDSLLEAIPQSYVLFADDSSLLTDSISFDGIMEAFSRCPKQSSPGLDDLPYSIVQLIVLHPLCKNIVVQMYNDALKLGIFPPFWLSTSVCLLPKKGDLFDLRNWRPISLINSDAKVFTRILNSRFLMVTDQMINPYQTGFVRGRFIADSRLSMKLLIEHARTSNSPAIALLLDQEKAYYQVHPLYRQLVLEKFGFPSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MVM0</accession>
    <name>A0A1C7MVM0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_11452</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01002045">
        <property type="protein sequence ID" value="OBZ80499.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MVM0"/>
    <dbReference type="STRING" id="101091.A0A1C7MVM0"/>
    <dbReference type="InParanoid" id="A0A1C7MVM0"/>
    <dbReference type="OrthoDB" id="2333384at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="74"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="142"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="80"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="152"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ80499.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="162" mass="18556" checksum="13F44C2C927CA4A4" modified="2016-11-30" version="1" fragment="single">SPPPSQSSHQPLPPPSQPTWLSKLRKPINAKEEGKHVIRKRETIRLETPIGVFDCRLKEDYGRLPSYSELNVTARPTVNQDDKSKKQEMLEQDMLHYNHSKSPESYQAASKEPQPQLCPCYFKFRRQMEMASQAQLLAANDNNNTTLERIPSIPPPDYVETA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MVW6</accession>
    <name>A0A1C7MVW6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_11024</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001597">
        <property type="protein sequence ID" value="OBZ80927.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MVW6"/>
    <dbReference type="STRING" id="101091.A0A1C7MVW6"/>
    <dbReference type="InParanoid" id="A0A1C7MVW6"/>
    <dbReference type="OrthoDB" id="2289822at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ80927.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="404" mass="45039" checksum="59457D0101BB99C4" modified="2016-11-30" version="1">MELTAHISSAQSTPSRNATNSVASDFEVASEDTNMSLNSDVDVGEVDFLVEPMNVDVSLPVTDENVNSTDRVTYNWTPCELLSETKAAWITVMQVLDEARTPTEYQRKLINVINSRILSHIDQGPFANDTFQSPDTYRRMVQGSTSTTVKHNICPNGCYLFGSDDSTTMACPVPACKAPCYFNQAKSDAAREDIERNSAMPIPDLAPTRQIIHLGRQGFNRTKAHQVLINCLVMNIYPEHRTKDENIIQITVCPGKPKNLISFLKSVVEEVQAMYDNKLVIKKEGVELFRGRVAILGVTGDIPGISELMMAAGHTVTFRCRICKVKDNKPHGVSNKGKYYPKMGPLCTLEKLKNGDPAHGMPDVPKLFTDLKTLTSLYFFFWRRIIHAGSWFGPHGIQVVRPQN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MWN3</accession>
    <name>A0A1C7MWN3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">pectinesterase</fullName>
            <ecNumber evidence="3">3.1.1.11</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Pectin methylesterase A</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">PMEU1_1</name>
        <name evidence="9" type="ORF">A0J61_11085</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Glycan metabolism; pectin degradation; 2-dehydro-3-deoxy-D-gluconate from pectin: step 1/5.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the pectinesterase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.11" evidence="3"/>
    <dbReference type="EMBL" id="LUGH01001659">
        <property type="protein sequence ID" value="OBZ80866.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MWN3"/>
    <dbReference type="STRING" id="101091.A0A1C7MWN3"/>
    <dbReference type="InParanoid" id="A0A1C7MWN3"/>
    <dbReference type="OrthoDB" id="1546079at2759"/>
    <dbReference type="UniPathway" id="UPA00545">
        <property type="reaction ID" value="UER00823"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030599">
        <property type="term" value="F:pectinesterase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042545">
        <property type="term" value="P:cell wall modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045490">
        <property type="term" value="P:pectin catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.20.10">
        <property type="entry name" value="Single-stranded right-handed beta-helix, Pectin lyase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012334">
        <property type="entry name" value="Pectin_lyas_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011050">
        <property type="entry name" value="Pectin_lyase_fold/virulence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000070">
        <property type="entry name" value="Pectinesterase_cat"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31321">
        <property type="entry name" value="ACYL-COA THIOESTER HYDROLASE YBHC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31321:SF57">
        <property type="entry name" value="PECTINESTERASE 53-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01095">
        <property type="entry name" value="Pectinesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51126">
        <property type="entry name" value="Pectin lyase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0063">Aspartyl esterase</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5011119403" description="pectinesterase" evidence="7">
        <location>
            <begin position="21"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="domain" description="Pectinesterase catalytic" evidence="8">
        <location>
            <begin position="28"/>
            <end position="319"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008891"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00042203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01095"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OBZ80866.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="333" mass="35836" checksum="5F370C39EB3F12BE" modified="2016-11-30" version="1">MKYSFSILLTFLVHATLALAAASVDVCSSCKYKTISAALASLPGGSTSYTINIAPGTYNERLNIERSNVVLAKKGSGTVLVQYAIAHNTQDPNSNASQKAVVTVGGSNVRFYDINIANVYKQTRNIATVALFIKGKQVSFYRSNIYGFQDTLLINENATAYFKSCYIEGSVDFIYGYGIGYFQTCTIASNAAGYITAHYRRTSNAAGGLYFNSCTTKATVPSGPLSKTANPSLSFTSSSKTANTSYLGRPWNQYARVVFIYSDIGAHINPAGWSAWSPTDPHTSNVFFAEYGNKGVHGSINGRKFVTKLSQAQANQYSAGGVFGSTSWIDTKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MXF2</accession>
    <name>A0A1C7MXF2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Transposable element Tcb1 transposase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">TCB1_0</name>
        <name evidence="1" type="ORF">A0J61_10834</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001430">
        <property type="protein sequence ID" value="OBZ81116.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MXF2"/>
    <dbReference type="STRING" id="101091.A0A1C7MXF2"/>
    <dbReference type="InParanoid" id="A0A1C7MXF2"/>
    <dbReference type="OrthoDB" id="2283219at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ81116.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="190" mass="21869" checksum="2D2AD249F2ABA673" modified="2016-11-30" version="1">MNNVICLDESCYEIEGHRGGLRVIRQQGQVYKEELAVPTKKFGKGSVMLWNCFWTGGAGPLVFVDGSPWLSDLQAKEDRTFTFQEDGATCHTDAATHAWKTRHMINGFEFWPAQSPDSNPIEHLWWAFELRVESRRHTVQNAAQLKELLLEAWNEISHDLLMRLVESIKDRYQAVIDAKGSPTRYNSRFI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MXR4</accession>
    <name>A0A1C7MXR4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Kinetochore protein Spc24</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_10745</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Component of the NDC80 complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Chromosome</location>
            <location evidence="1">Centromere</location>
            <location evidence="1">Kinetochore</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the SPC24 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001362">
        <property type="protein sequence ID" value="OBZ81206.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MXR4"/>
    <dbReference type="InParanoid" id="A0A1C7MXR4"/>
    <dbReference type="OrthoDB" id="2263770at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000776">
        <property type="term" value="C:kinetochore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013252">
        <property type="entry name" value="Ndc80_Spc24"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08286">
        <property type="entry name" value="Spc24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="1" id="KW-0132">Cell division</keyword>
    <keyword evidence="1" id="KW-0137">Centromere</keyword>
    <keyword evidence="1" id="KW-0158">Chromosome</keyword>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0995">Kinetochore</keyword>
    <keyword evidence="1" id="KW-0498">Mitosis</keyword>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="21"/>
            <end position="118"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU368011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ81206.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="165" mass="19024" checksum="241F86D62AFBDF58" modified="2016-11-30" version="1">MESITHEIQQLKETLNHYGLSKQLEETLKSERTAKDKAEKIMRDMEADIKALKHQYALLQQQEKSFESEFESYISKQAQLEEEEIQLVDQVMLKENEAHQLNQEVEQLKAELDAIGKETAPSLDSPHELNQLYLSIYRGLGVIGKMEENGQVNKFVLSKVDQTTC</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MY07</accession>
    <name>A0A1C7MY07_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Yeast cell wall synthesis Kre9/Knh1-like N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">A0J61_10247</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001086">
        <property type="protein sequence ID" value="OBZ81703.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MY07"/>
    <dbReference type="STRING" id="101091.A0A1C7MY07"/>
    <dbReference type="InParanoid" id="A0A1C7MY07"/>
    <dbReference type="OrthoDB" id="2278575at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018466">
        <property type="entry name" value="Kre9/Knh1-like_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10342">
        <property type="entry name" value="Kre9_KNH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008889354" description="Yeast cell wall synthesis Kre9/Knh1-like N-terminal domain-containing protein" evidence="3">
        <location>
            <begin position="21"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="domain" description="Yeast cell wall synthesis Kre9/Knh1-like N-terminal" evidence="4">
        <location>
            <begin position="27"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="120"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="126"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="148"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="187"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="199"/>
            <end position="245"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF10342"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OBZ81703.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="245" mass="26803" checksum="39E492E3F0357229" modified="2016-11-30" version="1">MLKSALALLSFSAILQLIGASSVTITQPKSNDVLKAGTEIKIKWDINEASTETIRLQYASGPSQELTIDGVIAENVKASLGQYVWKIPSDIKPKQYVIEAGPNDNDISFAGYVTVKAGKKTDSKSTKKTTKKTTKKTTKKKTTTKKSKKDDNKKPTKETNERKTSAVCVGYPSADKTPQRVRCHSVPKPDAKKVEKASKKSTKKSSKKSTKKSTKKSTKKPTKKSAKKSAKKATKKTTKKSVKHN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MYR1</accession>
    <name>A0A1C7MYR1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="9">K(+)/H(+) antiporter 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">kha1_1</name>
        <name evidence="9" type="ORF">A0J61_10031</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001007">
        <property type="protein sequence ID" value="OBZ81921.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MYR1"/>
    <dbReference type="FunCoup" id="A0A1C7MYR1">
        <property type="interactions" value="17"/>
    </dbReference>
    <dbReference type="InParanoid" id="A0A1C7MYR1"/>
    <dbReference type="OrthoDB" id="2687058at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015297">
        <property type="term" value="F:antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902600">
        <property type="term" value="P:proton transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1530.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006153">
        <property type="entry name" value="Cation/H_exchanger_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050794">
        <property type="entry name" value="CPA2_transporter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038770">
        <property type="entry name" value="Na+/solute_symporter_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32468">
        <property type="entry name" value="CATION/H + ANTIPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32468:SF0">
        <property type="entry name" value="K(+)_H(+) ANTIPORTER 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00999">
        <property type="entry name" value="Na_H_Exchanger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0406">Ion transport</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="28"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="57"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="88"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="120"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="155"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="189"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="220"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="259"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="333"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="366"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="398"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="domain" description="Cation/H+ exchanger transmembrane" evidence="8">
        <location>
            <begin position="38"/>
            <end position="414"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00999"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OBZ81921.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="743" mass="82054" checksum="3533824C3198DDBA" modified="2016-11-30" version="1">MSENQTAVPQAGVFAGLNPTHFNPSDPLVLFIIQATIILAFCRIIAIPLGYLKQPQFIVIAGILLGPTVMGRIPGFQQTIFPTPSLPFLHLVANLGLVFFLFQVGLEVDVQVIKRDWHKSLSVAVAGMALPFGLGAAVSVGLYQLQQDSSISFSSFLLFLGVAMSITAFPVLARILAELKLLRTKVGAITMAAGLINDCTAWVLLALVVALLNSSGGMDALYVFLTAIAFTLFILFLVGPLYRKLCVITHSFEHGPSPLLMAVTLMIVLLSAFVTSIIGFLAGVIVPHEHDLAVKITEKIEDLVNIIFLPLVSQYFTLSGLKTQIGLLNSGSVWGYVILVIFLACFGKIVGCTLAARLTKMTTREALTVGFLMNCKGLVELIVLNIGHDAGVLNDQIFVIMVVMALVTTFMTTPAVIYLYPEWYQKQTTNDPSLTNPMDMAMQKQKVLNHYCLLSLVNKAESIPAVMALIQLMKNNPLSSIEIHALRLLELTERASAVMKYKDMQYDPVLNVLFTFAQLSHLHALLKTHLDYCLSTDYIKTVCRYRSEVNADMVVLPLMDPEADLELIHELFGIQHAPVGLFVDRGVCVQESHRPSQIVVLFRYHQDDRAALVFSLWMQAYRKVDLTVLVESDEKKVRYASVDTIGQYVQTQDGSLDLLFSDENQVSNVVCCTVNERLSGQLLSKALARPLEHHDVVILGRRSLEEEECVGHDKEYEKAVGQLGSDILKHSLQTSLFIVQSPF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MYW1</accession>
    <name>A0A1C7MYW1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_09994</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000996">
        <property type="protein sequence ID" value="OBZ81958.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MYW1"/>
    <dbReference type="InParanoid" id="A0A1C7MYW1"/>
    <dbReference type="OrthoDB" id="2404656at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ81958.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="141" mass="15992" checksum="5AF83325A7CEB46A" modified="2016-11-30" version="1">MNLVLLFASSGKNYKDLEHSRDDTLKNVHGSICALEAILRRYPNASFATASSLLSFTVQSISTTIKLSTTALDAENIDSFLHQECRSVHYDERIEWMKVFELVSKLVMMLREQALIIDQLQKEQSGIIPIDNVETVRFVLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MZH5</accession>
    <name>A0A1C7MZH5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">SET domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_10128</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001044">
        <property type="protein sequence ID" value="OBZ81826.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MZH5"/>
    <dbReference type="FunCoup" id="A0A1C7MZH5">
        <property type="interactions" value="208"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7MZH5"/>
    <dbReference type="InParanoid" id="A0A1C7MZH5"/>
    <dbReference type="OrthoDB" id="6627536at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042799">
        <property type="term" value="F:histone H4K20 methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.270.10">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001214">
        <property type="entry name" value="SET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046341">
        <property type="entry name" value="SET_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039977">
        <property type="entry name" value="Suv4-20/Set9"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12977:SF4">
        <property type="entry name" value="HISTONE-LYSINE N-METHYLTRANSFERASE KMT5B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12977">
        <property type="entry name" value="SUPPRESSOR OF VARIEGATION 4-20-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00856">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82199">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SET" evidence="2">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="65"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="246"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="83"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="275"/>
            <end position="286"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00856"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ81826.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="401" mass="46356" checksum="58142E0EF92959B0" modified="2016-11-30" version="1">MNHDCDANCSFILIGQNAITFRVERDIKCGEEMTVFYAEHYFGEYNCECRCCSCERLQQGSFSVQQSEDEGESSLDENGNARRSIRKRKRVNYKGKPRHGHKQPIDTCLDYFVLGQVKRAKHAEALKETTNLELASPSSVDLSQSEQGETQKAKLFDLNWSRQELDKMSRVYNWMDAQSDLSDDDNDDCNDRSRVLRKGHLNEVRCCDYADEFGIVKESTDSLRCARCYRHYKIFNHEWPLRRPRRTYGRQKQKISSIPSPPSPLSPPLSLMSPTRTRSSLNSKPPSTLDRLKTLSDQGPRIIKAWSTLEVAPICIEAAAPTIHRLEETLLADEHKHTDLPKSTHYNKSQTKTERIHVLTEKRTILQQLLERYKELLDYQQNTNYQADQEETEVCVIDPSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MZV5</accession>
    <name>A0A1C7MZV5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">HECT-type E3 ubiquitin transferase</fullName>
            <ecNumber evidence="3">2.3.2.26</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">UBE3A_1</name>
        <name evidence="9" type="ORF">A0J61_09561</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.</text>
            <dbReference type="EC" id="2.3.2.26"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.26" evidence="3"/>
    <dbReference type="EMBL" id="LUGH01000879">
        <property type="protein sequence ID" value="OBZ82387.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MZV5"/>
    <dbReference type="STRING" id="101091.A0A1C7MZV5"/>
    <dbReference type="InParanoid" id="A0A1C7MZV5"/>
    <dbReference type="OrthoDB" id="8068875at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000209">
        <property type="term" value="P:protein polyubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00078">
        <property type="entry name" value="HECTc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.2160.10:FF:000004">
        <property type="entry name" value="probable E3 ubiquitin-protein ligase HERC4 isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.2410.10:FF:000003">
        <property type="entry name" value="probable E3 ubiquitin-protein ligase HERC4 isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2160.10">
        <property type="entry name" value="Hect, E3 ligase catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2410.10">
        <property type="entry name" value="Hect, E3 ligase catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1750.10">
        <property type="entry name" value="Hect, E3 ligase catalytic domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044611">
        <property type="entry name" value="E3A/B/C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000569">
        <property type="entry name" value="HECT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035983">
        <property type="entry name" value="Hect_E3_ubiquitin_ligase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45700:SF8">
        <property type="entry name" value="HECT-TYPE E3 UBIQUITIN TRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45700">
        <property type="entry name" value="UBIQUITIN-PROTEIN LIGASE E3C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00632">
        <property type="entry name" value="HECT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00119">
        <property type="entry name" value="HECTc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56204">
        <property type="entry name" value="Hect, E3 ligase catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50237">
        <property type="entry name" value="HECT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9" id="KW-0436">Ligase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="6 7" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="HECT" evidence="8">
        <location>
            <begin position="93"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="active site" description="Glycyl thioester intermediate" evidence="7">
        <location>
            <position position="390"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OBZ82387.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="605" mass="70075" checksum="16523D95E459E00F" modified="2016-11-30" version="1" fragment="single">FYNDAVNDQLEIKEDFPNFKDKKGFSFCDYPFMLNPAVKADVLKVESVFQMRHELQDAFFRALFQGVNSPYLVLEIRRDHIISDTLLQLEEKSIHDLKKQLRVQFVGEEGVDEGGVQKEFFQLIVREIFDPKYGMFTFNEESRLCWFTPNPVLDEINIREYKLVGLLLGLAVYNSVILDLHFPLVLYKKLMQVNTTLSDLKQLDPSLGKGLERLLNFEGDIVTEYDRNFQVDIQSFGHVYTCDLKPFGSNIQLTNENKHEFVDLYVQFVLTDCIEKQFNAFKEGFQLVCQDSAIKIFRPEEVEQLICGSSDLDFDALEASTVYDGGWSKDSDIIKYFWEIVHSFTYEEKKKLLFFATGSDRAPIGGLGKLQFVIAKNGGDSDRLPTSHTCYNVLLLCEYSSKEKLKERLLTSISNAEGFDHYFTKRKQRLSQPAQKTKEATNHVVQAPEPVYEITKKAPKQIIKKNSILYYLSQPRTRDEKKEEQEEQQQCQIRMSLPLSDIWHAVLEEFDASSITPAFTPILPQPSSSLLPLANSRKRQTLEDNDGTRNVRLRLHANPVTWCLEEDLQETDEDLSRPTRNRYSLETTQLYLLAVTREFSDDLWC</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MZW9</accession>
    <name>A0A1C7MZW9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ATPase family gene 2 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">afg2</name>
        <name evidence="5" type="ORF">A0J61_09985</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000993">
        <property type="protein sequence ID" value="OBZ81966.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MZW9"/>
    <dbReference type="STRING" id="101091.A0A1C7MZW9"/>
    <dbReference type="InParanoid" id="A0A1C7MZW9"/>
    <dbReference type="OrthoDB" id="27435at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd19511">
        <property type="entry name" value="RecA-like_CDC48_r2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000661">
        <property type="entry name" value="calmodulin-interacting protein 111 isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.60:FF:000069">
        <property type="entry name" value="spermatogenesis-associated protein 5 isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050168">
        <property type="entry name" value="AAA_ATPase_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041569">
        <property type="entry name" value="AAA_lid_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23077">
        <property type="entry name" value="AAA-FAMILY ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23077:SF27">
        <property type="entry name" value="ATPASE FAMILY GENE 2 PROTEIN HOMOLOG A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17862">
        <property type="entry name" value="AAA_lid_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="4">
        <location>
            <begin position="119"/>
            <end position="245"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OBZ81966.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="340" mass="37592" checksum="5E26FA67F58FE8A2" modified="2016-11-30" version="1">MKKTPNTLEEEQFESLSSKLHGYVGADIAAVCREAGLKCIKRCAAANSMPLGQLAVNLQDMKEAMAEIRPSAMREIMLEVPKVYWTDVAGQADIKQRLKESVEWPLQHPEAFLRLGIRPPKGILLYGPPGCSKTLMAKALATEAGSNFIAVKGPELFSKWVGESEKAVHEVFRKARAASPSIVFFDEIDALTVKRGASGDGGTSVADRVLSQLLNELDGVEALVNDDALLRPGRIDRILYVGPPDIHSRKEIFRIQTGKMRCDKDVDIDIIAEKSEGCSGAEAVAICQEAALFAMEEDVHIESVKMRHFQKALDSFTRRITPEMLQFYKDFQERSGLQSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N133</accession>
    <name>A0A1C7N133_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_09616</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000892">
        <property type="protein sequence ID" value="OBZ82329.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="InParanoid" id="A0A1C7N133"/>
    <dbReference type="OrthoDB" id="2288597at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="116"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ82329.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="116" mass="13568" checksum="918B7729AB86273F" modified="2016-11-30" version="1" fragment="single">MSEQYEQLTPEEIKEFRALKQRLQAQELRDEGQRDLPEEIHLELEETSRFNLKKKXKQYHRDTIKYEGGKWTQTGTINKVYLPELKRYQCDAAQMVSAIGKGADRLRTAGRGATEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N177</accession>
    <name>A0A1C7N177_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">PH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_09052</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000763">
        <property type="protein sequence ID" value="OBZ82895.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N177"/>
    <dbReference type="STRING" id="101091.A0A1C7N177"/>
    <dbReference type="InParanoid" id="A0A1C7N177"/>
    <dbReference type="OrthoDB" id="2123378at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001849">
        <property type="entry name" value="PH_domain"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50003">
        <property type="entry name" value="PH_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PH" evidence="2">
        <location>
            <begin position="417"/>
            <end position="551"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="131"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="166"/>
            <end position="186"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ82895.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="562" mass="64069" checksum="9FAD67FA26A3D1B0" modified="2016-11-30" version="1">MEGEHNEDGCRVNVYGDVFDLLFNSKHGYKTKRSECHSQTIKALKANGLVDVEEKDVRLDFILTNSTGIQDLSLYLITNGAGIAEYLTAVIPLVRMVTWNFEAIQLMIQTAQQDNMTFLVKPATSKIFYREDSPASEGSDITNTNSSSSTAPSHVYSSSFVLEDHDGDDEEEEYTPLQYIDDDDDDIPFPDYIPSRLSVSSSAQKEDVEPTEPESVCIAYQDAPTDQLPMKQYFFIKVLRVENLDFPIEKDTTGVYCTIRYKDHISTSTEQRLQHNLQFNHDMRIDPIDMQAQIAITLHATKKTIGSHWYHKMKSGSDLNRYIHEKDSSLCQTLLPLSQFIPSDKTVALLLTNNWYRPQTESSLFQLIKKKPVAKEKGVGKIILQCLTIDIRSDADYVPHDMDEAMEALNAKRFYQTQWQSGYMMVITQSGLNNKHMYFTLTGGSLVAHATQDSLPAYQIPLARAIKLLCDGRVISERPLYQYPMQKPATIISELESVILSSEEEEDRPRRPISLTNRFELLFDNEETIQFECDSIDDLTKWVTLITVIMSKLPKLPDWIQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N251</accession>
    <name>A0A1C7N251_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Phenylalanine--tRNA ligase, mitochondrial</fullName>
            <ecNumber evidence="3">6.1.1.20</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">Phenylalanyl-tRNA synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="17" type="primary">Fars2</name>
        <name evidence="17" type="ORF">A0J61_08871</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">Is responsible for the charging of tRNA(Phe) with phenylalanine in mitochondrial translation.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>tRNA(Phe) + L-phenylalanine + ATP = L-phenylalanyl-tRNA(Phe) + AMP + diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:19413"/>
            <dbReference type="Rhea" id="RHEA-COMP:9668"/>
            <dbReference type="Rhea" id="RHEA-COMP:9699"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58095"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78531"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.20"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion matrix</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the class-II aminoacyl-tRNA synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.20" evidence="3"/>
    <dbReference type="EMBL" id="LUGH01000725">
        <property type="protein sequence ID" value="OBZ83081.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N251"/>
    <dbReference type="FunCoup" id="A0A1C7N251">
        <property type="interactions" value="511"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N251"/>
    <dbReference type="InParanoid" id="A0A1C7N251"/>
    <dbReference type="OrthoDB" id="4457at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004826">
        <property type="term" value="F:phenylalanine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070156">
        <property type="term" value="P:mitochondrial phenylalanyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd00496">
        <property type="entry name" value="PheRS_alpha_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.380:FF:000002">
        <property type="entry name" value="phenylalanine--tRNA ligase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.930.10:FF:000053">
        <property type="entry name" value="Phenylalanyl-tRNA synthetase mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="entry name" value="Bira Bifunctional Protein, Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.380">
        <property type="entry name" value="Ferrodoxin-fold anticodon-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006195">
        <property type="entry name" value="aa-tRNA-synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005121">
        <property type="entry name" value="Fdx_antiC-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036690">
        <property type="entry name" value="Fdx_antiC-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004530">
        <property type="entry name" value="Phe-tRNA-synth_IIc_mito"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002319">
        <property type="entry name" value="Phenylalanyl-tRNA_Synthase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00469">
        <property type="entry name" value="pheS_mito"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11538:SF41">
        <property type="entry name" value="PHENYLALANINE--TRNA LIGASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11538">
        <property type="entry name" value="PHENYLALANYL-TRNA SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03147">
        <property type="entry name" value="FDX-ACB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01409">
        <property type="entry name" value="tRNA-synt_2d"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00896">
        <property type="entry name" value="FDX-ACB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54991">
        <property type="entry name" value="Anticodon-binding domain of PheRS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="Class II aaRS and biotin synthetases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50862">
        <property type="entry name" value="AA_TRNA_LIGASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51447">
        <property type="entry name" value="FDX_ACB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 17" id="KW-0436">Ligase</keyword>
    <keyword evidence="9" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="Aminoacyl-transfer RNA synthetases class-II family profile" evidence="15">
        <location>
            <begin position="159"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="domain" description="FDX-ACB" evidence="16">
        <location>
            <begin position="333"/>
            <end position="425"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004305"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012814"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00031194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00049255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00057761"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00073229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS51447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="OBZ83081.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="425" mass="49200" checksum="ECF34B92AC6923D2" modified="2016-11-30" version="1">MLRTSFRLAQTSHRVNINSACGFLSISRNCYYSTSAEFEINAKETVINGKHLPRDDWTNVSPTVLSKINRKLYLQPKNPISIIRQLIESNFKDFDTYNNFDPIVTTKQNFDDLHIPADHPSRTKSDNYYFNKETVLRAHTSAHQLQGLASGSSKFLISGDVYRRDEIDSSHYPVFHQIEGFFYVDNNLTKLDQALKHIKQDKSSNIDLVDDTLIKPENPYQDCHLPESVDLISAHLKHSINAMIRNLFADEPNLKVRWIDAYFPFTSPSWEVEIFYKGEWLEVLGCGVVNQKIMNQAGLNDKIGWAFGMGLERLAMVLFGIPDIRLFWSEDPRFIEQFTPDISFWLPEGQWSENDFCELVRGAAGDIVETVDLIDDFTHPKTKRRSLCYRINYRSMDRNVTNEEINSIQEKVRSVVQNELNVELR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N257</accession>
    <name>A0A1C7N257_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Anucleate primary sterigmata protein A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">apsA_0</name>
        <name evidence="2" type="ORF">A0J61_08757</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000705">
        <property type="protein sequence ID" value="OBZ83193.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N257"/>
    <dbReference type="STRING" id="101091.A0A1C7N257"/>
    <dbReference type="InParanoid" id="A0A1C7N257"/>
    <dbReference type="OrthoDB" id="2149224at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005938">
        <property type="term" value="C:cell cortex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015631">
        <property type="term" value="F:tubulin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000226">
        <property type="term" value="P:microtubule cytoskeleton organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.1490">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053005">
        <property type="entry name" value="Nuclear_Pos-Cytoskel_Interact"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28190">
        <property type="entry name" value="NUCLEAR MIGRATION PROTEIN NUM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28190:SF1">
        <property type="entry name" value="NUCLEAR MIGRATION PROTEIN NUM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="318"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="360"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="465"/>
            <end position="572"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="805"/>
            <end position="826"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="8"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="25"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="45"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="104"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="139"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="380"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="478"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="500"/>
            <end position="511"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="536"/>
            <end position="561"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="807"/>
            <end position="826"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="843"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ83193.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="843" mass="91927" checksum="6355546DED8566E6" modified="2016-11-30" version="1" fragment="single">MSTPPPKHSLSSPTSANTPQPVLPTPSSSTTVSRSINKTQQQQRQELEQQLAEKQKQLQESSSGIGKNVLARQVSQLEEKLREMDSQSPDGFPQSPPLAGSAVDRLKSLERDLSSYRSHPLSPGISSIRGKDKLLNQRSPTPTGLDPLPSPTTSTLLPPAHGHDSTSLLPLPPPPTGSTPTKRRSKVPNTDRRNTDIEFATEIGQGLLLEVRKMQALLQEKEEKLRTLENQKADLERAAEAMAKQMRQREENEEKLKEETWNLELAKQELVISVTDLQTNLTKANAEQNKLAKQVNELRSEIEQLRDREEKLNKSIEAMKQRHEQDMSSIRRHAAAIQREKADQTKQIEALTSELAIAKAQSRIGKHTSSEGEPSHRRSTTAGDSALSDQGHSATAVKSDTSPSSSPPSSPKQSPARNQAMEVETLKSSLAHAHRMVNNLRTGLHKEKNEKFELKKLLAESQETIEHLQNDPRLWVDAGTARAAGSSSGPSSRNEDGSRRALKTNKRRGGKKNTFDSTTGKRKTKFSKTNARFAGDDEDQEEYSDLSDNEESDADSYDESDLNSPTVKLGGFTSLSSELSQGQKPIIVSTEVIAEPIEDLSMRPTSLADELATGSRSLGDELSSAMSRSSTNEEVFQKEKVQGIEISIQTDIELSTPTKEFVEISVQTDTVSVPSEISTQTEPRAPLEQKTIGSLVIEPTRFALHSATQVGIDVAPEDPEIASAALAAATAAAIASARQAAIESAIDVSTQSEAILTQDHETQSVPTPSLDQGVQAESFEGVDCGIQSETSQYVDVSVQSDSPVLADSKDVSVQHEELEESRDSAAAKVPFTEHVETVDESTQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N299</accession>
    <name>A0A1C7N299_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">purine-nucleoside phosphorylase</fullName>
            <ecNumber evidence="3">2.4.2.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Inosine-guanosine phosphorylase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">A0J61_08706</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Purine metabolism; purine nucleoside salvage.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the PNP/MTAP phosphorylase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.2.1" evidence="3"/>
    <dbReference type="EMBL" id="LUGH01000697">
        <property type="protein sequence ID" value="OBZ83240.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N299"/>
    <dbReference type="FunCoup" id="A0A1C7N299">
        <property type="interactions" value="330"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N299"/>
    <dbReference type="InParanoid" id="A0A1C7N299"/>
    <dbReference type="OrthoDB" id="10261782at2759"/>
    <dbReference type="UniPathway" id="UPA00606"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004731">
        <property type="term" value="F:purine-nucleoside phosphorylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009116">
        <property type="term" value="P:nucleoside metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd09009">
        <property type="entry name" value="PNP-EcPNPII_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1580">
        <property type="entry name" value="Nucleoside phosphorylase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000845">
        <property type="entry name" value="Nucleoside_phosphorylase_d"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035994">
        <property type="entry name" value="Nucleoside_phosphorylase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011268">
        <property type="entry name" value="Purine_phosphorylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018099">
        <property type="entry name" value="Purine_phosphorylase-2_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01697">
        <property type="entry name" value="PNPH-PUNA-XAPA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006054">
        <property type="entry name" value="PRK08202.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11904">
        <property type="entry name" value="METHYLTHIOADENOSINE/PURINE NUCLEOSIDE PHOSPHORYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11904:SF9">
        <property type="entry name" value="PURINE NUCLEOSIDE PHOSPHORYLASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01048">
        <property type="entry name" value="PNP_UDP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000477">
        <property type="entry name" value="PurNPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53167">
        <property type="entry name" value="Purine and uridine phosphorylases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01240">
        <property type="entry name" value="PNP_MTAP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Nucleoside phosphorylase" evidence="8">
        <location>
            <begin position="29"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="35"/>
        </location>
        <ligand>
            <name>phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="68"/>
        </location>
        <ligand>
            <name>phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="90"/>
            <end position="92"/>
        </location>
        <ligand>
            <name>phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="122"/>
        </location>
        <ligand>
            <name>phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="208"/>
        </location>
        <ligand>
            <name>a purine D-ribonucleoside</name>
            <dbReference type="ChEBI" id="CHEBI:142355"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="227"/>
        </location>
        <ligand>
            <name>phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="250"/>
        </location>
        <ligand>
            <name>a purine D-ribonucleoside</name>
            <dbReference type="ChEBI" id="CHEBI:142355"/>
        </ligand>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="316"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005058"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006751"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011886"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00031036"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR000477-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OBZ83240.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="316" mass="34328" checksum="D1F7FD1FC9CED574" modified="2016-11-30" version="1" fragment="single">MATITEETYQSSADFLRSKLPQDFQKIDLGIICGSGLGGLVDTLDEKTKVEFAYQDIPGFVSSTVAGHAGKLVFGHLGESRTPTVFMVGRFHYYEGWSMQQVTLPVRVMVLLGIRYLVVTNACGGLQPEHKVGDLMIINDHLSIPGMVGNNPLMGPNLESFGPRFPAVSDAYTYALRKLAFKAAFEVGIAQDDIREGVYCMVTGPSFETRVEARYLASIGADVVGMSTIPETVIARHAGVKVLGISLVTNAVITARGKDAKLEVLREMGLSTEEDKEEDTEKTFANHAEVLETSAKRSGDMQRMVTRFADLLAAAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N2P2</accession>
    <name>A0A1C7N2P2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">[acyl-carrier-protein] S-malonyltransferase</fullName>
            <ecNumber evidence="2">2.3.1.39</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">fabD</name>
        <name evidence="7" type="ORF">A0J61_10329</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>holo-[ACP] + malonyl-CoA = malonyl-[ACP] + CoA</text>
            <dbReference type="Rhea" id="RHEA:41792"/>
            <dbReference type="Rhea" id="RHEA-COMP:9623"/>
            <dbReference type="Rhea" id="RHEA-COMP:9685"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57384"/>
            <dbReference type="ChEBI" id="CHEBI:64479"/>
            <dbReference type="ChEBI" id="CHEBI:78449"/>
            <dbReference type="EC" id="2.3.1.39"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the FabD family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.39" evidence="2"/>
    <dbReference type="EMBL" id="LUGH01001120">
        <property type="protein sequence ID" value="OBZ81624.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N2P2"/>
    <dbReference type="FunCoup" id="A0A1C7N2P2">
        <property type="interactions" value="351"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N2P2"/>
    <dbReference type="InParanoid" id="A0A1C7N2P2"/>
    <dbReference type="OrthoDB" id="541883at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004314">
        <property type="term" value="F:[acyl-carrier-protein] S-malonyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.250">
        <property type="entry name" value="Malonyl-CoA ACP transacylase, ACP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.366.10">
        <property type="entry name" value="Malonyl-Coenzyme A Acyl Carrier Protein, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001227">
        <property type="entry name" value="Ac_transferase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014043">
        <property type="entry name" value="Acyl_transferase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016035">
        <property type="entry name" value="Acyl_Trfase/lysoPLipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050858">
        <property type="entry name" value="Mal-CoA-ACP_Trans/PKS_FabD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024925">
        <property type="entry name" value="Malonyl_CoA-ACP_transAc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004410">
        <property type="entry name" value="Malonyl_CoA-ACP_transAc_FabD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016036">
        <property type="entry name" value="Malonyl_transacylase_ACP-bd"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00128">
        <property type="entry name" value="fabD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42681">
        <property type="entry name" value="MALONYL-COA-ACYL CARRIER PROTEIN TRANSACYLASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42681:SF1">
        <property type="entry name" value="MALONYL-COA-ACYL CARRIER PROTEIN TRANSACYLASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00698">
        <property type="entry name" value="Acyl_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000446">
        <property type="entry name" value="Mct"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00827">
        <property type="entry name" value="PKS_AT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52151">
        <property type="entry name" value="FabD/lysophospholipase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55048">
        <property type="entry name" value="Probable ACP-binding domain of malonyl-CoA ACP transacylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Malonyl-CoA:ACP transacylase (MAT)" evidence="6">
        <location>
            <begin position="23"/>
            <end position="325"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013258"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00048462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OBZ81624.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="334" mass="37003" checksum="8953AAE49362BC19" modified="2016-11-30" version="1">MHRCISQRWMSINAQSTLKRAILFPGQGSQYVGMGKELHDRYAVARQVFEEADQALGYDQRALVFRGQQEVLKLTENAQPAILTTSIALLRVLQEDQVDLTNSGWFGLGHSLGEYTALVAAGSLSLTDAVRLVRLRGESMTRAVADRRTAMSALVVRKGKLNDLLESMQFLQAELPKEDHVSIANINSSFQVVLSGTSYGVDYASRALQAKRFAAKAVDLPVSAPFHCALMQEAADVMQEALTKVEIKMPLMPVISNVTAKPYTSTQAILERLVEQVVAPVQWERSIAYCKKQGVDDFLCIGPGKVLANLLKKEYPLDRIRTMNTVEDIPQCMD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N2S9</accession>
    <name>A0A1C7N2S9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Isoleucine--tRNA ligase, mitochondrial</fullName>
            <ecNumber evidence="4">6.1.1.5</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Isoleucyl-tRNA synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="15" type="primary">ileS</name>
        <name evidence="15" type="ORF">A0J61_08603</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>tRNA(Ile) + L-isoleucine + ATP = L-isoleucyl-tRNA(Ile) + AMP + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:9666"/>
            <dbReference type="Rhea" id="RHEA-COMP:9695"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58045"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78528"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.5"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the class-I aminoacyl-tRNA synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.5" evidence="4"/>
    <dbReference type="EMBL" id="LUGH01000679">
        <property type="protein sequence ID" value="OBZ83347.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N2S9"/>
    <dbReference type="FunCoup" id="A0A1C7N2S9">
        <property type="interactions" value="557"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N2S9"/>
    <dbReference type="InParanoid" id="A0A1C7N2S9"/>
    <dbReference type="OrthoDB" id="10264412at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002161">
        <property type="term" value="F:aminoacyl-tRNA deacylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004822">
        <property type="term" value="F:isoleucine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006428">
        <property type="term" value="P:isoleucyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032543">
        <property type="term" value="P:mitochondrial translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd07960">
        <property type="entry name" value="Anticodon_Ia_Ile_BEm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00818">
        <property type="entry name" value="IleRS_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.740.10:FF:000009">
        <property type="entry name" value="Isoleucyl-tRNA synthetase 2, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.620:FF:000111">
        <property type="entry name" value="Mitochondrial isoleucyl-tRNA synthetase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.730.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.740.10">
        <property type="entry name" value="Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02002">
        <property type="entry name" value="Ile_tRNA_synth_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002300">
        <property type="entry name" value="aa-tRNA-synth_Ia"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033708">
        <property type="entry name" value="Anticodon_Ile_BEm"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002301">
        <property type="entry name" value="Ile-tRNA-ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023585">
        <property type="entry name" value="Ile-tRNA-ligase_type1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050081">
        <property type="entry name" value="Ile-tRNA_ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013155">
        <property type="entry name" value="M/V/L/I-tRNA-synth_anticd-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009080">
        <property type="entry name" value="tRNAsynth_Ia_anticodon-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009008">
        <property type="entry name" value="Val/Leu/Ile-tRNA-synth_edit"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00392">
        <property type="entry name" value="ileS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42765:SF1">
        <property type="entry name" value="ISOLEUCINE--TRNA LIGASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42765">
        <property type="entry name" value="SOLEUCYL-TRNA SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08264">
        <property type="entry name" value="Anticodon_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00133">
        <property type="entry name" value="tRNA-synt_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00984">
        <property type="entry name" value="TRNASYNTHILE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47323">
        <property type="entry name" value="Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52374">
        <property type="entry name" value="Nucleotidylyl transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50677">
        <property type="entry name" value="ValRS/IleRS/LeuRS editing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 15" id="KW-0436">Ligase</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aminoacyl-tRNA synthetase class Ia" evidence="13">
        <location>
            <begin position="71"/>
            <end position="691"/>
        </location>
    </feature>
    <feature type="domain" description="Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding" evidence="14">
        <location>
            <begin position="735"/>
            <end position="892"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005594"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013165"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00032665"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00048359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00068280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF00133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF08264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="OBZ83347.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="984" mass="112753" checksum="E1F6152625CCA766" modified="2016-11-30" version="1">MLSLRSIRLEPRYTTLSRKLWSSAVVSAKATENPYTKTILLPKTSFPLRAEAAKREHLFKDRCTKDLYPWQLKNNPKDTFILHDGPPYANGNVHSGHAMNKILKDIVNRYKMLQGHKVFYRPGWDCHGLPIELKALEQIRKKGKEATALSPTEIRKIAREKALSEVEKQMASFKSWGVMGDWDDPYLTLSNDYEIRQLRVLTDMIKNGYIYRQLKPVYWSPSSKSALAESELEYNENHVSKSIHVRFPLTQLSSSLKDKWHHHLKGDNRLFALIWTTTPWTIPSNKAISVHPELSYSLIKVLDGSHQGAYIIASDRIDAFKQEMKVDHVEVVDQVQGDDLLGSQYIHPLNKEELSIIGAGHVTAESGTGLVHTAPAHGMEDYEACLKQNISITSLVDDNGKFTKEAGEYLEGKFAFTEGNDTVIEMLKNQAALVLQSDYTHKYPYDWRTKKPVMLRATAQWFANVENLQKQAVENLKRIRMIPDVSIHRLEQFTLSRKEWCISRQRAWGVPIPALYDQDGNALLTETSVEYIIKILQERGTDAWWEEKDDSVFVAPEYRQEGKVYKRGYDTMDVWFDSGTSWTMLNTVSNRDPTKPLADVYLEGSDQHRGWFQSSLLTSVAVTGKAPYGTLVTHGFALDEKGDKMSKSLGNTLEPALITDGGKDKKKNPAYGSDVLRLWVANCEYTRDVSIGPSIIAQISDSLRKVRTTARFMLGNLHDFSEKDYVEYDQLQEIDKYMLHELHNYNSRVTSAYNDFAFNRVVQNVFNFTNTTLSSFYFDTIKDRLYNEDASSHARRMAQTVLYELLKSYNVSLAPFICHTAEEIYDHYKHITSNPESSVFKTGWIQSNQQWNNPALSDKWSTLLDLKSQVNQVLESARQEKHIRSSQEADITVYLDKDVSLRKTLESLDASEITSLFMTSQVNIKEKTESFLQNEFERDAVIEGDECKIVLGKSKYSKCPRCWNYQSSEENALCQRCSTVLNKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N3N9</accession>
    <name>A0A1C7N3N9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">General transcription and DNA repair factor IIH</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="primary">tfh47</name>
        <name evidence="15" type="ORF">A0J61_08217</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to TFIIK, in RNA transcription by RNA polymerase II.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 11">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the GTF2H2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000612">
        <property type="protein sequence ID" value="OBZ83733.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N3N9"/>
    <dbReference type="FunCoup" id="A0A1C7N3N9">
        <property type="interactions" value="369"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N3N9"/>
    <dbReference type="InParanoid" id="A0A1C7N3N9"/>
    <dbReference type="OrthoDB" id="284275at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000112">
        <property type="term" value="C:nucleotide-excision repair factor 3 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000439">
        <property type="term" value="C:transcription factor TFIIH core complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005675">
        <property type="term" value="C:transcription factor TFIIH holo complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016251">
        <property type="term" value="F:RNA polymerase II general transcription initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006289">
        <property type="term" value="P:nucleotide-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006367">
        <property type="term" value="P:transcription initiation at RNA polymerase II promoter"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd01453">
        <property type="entry name" value="vWA_transcription_factor_IIH_type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.410:FF:000015">
        <property type="entry name" value="General transcription factor IIH subunit 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.410">
        <property type="entry name" value="von Willebrand factor, type A domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046349">
        <property type="entry name" value="C1-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007198">
        <property type="entry name" value="Ssl1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004595">
        <property type="entry name" value="TFIIH_C1-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012170">
        <property type="entry name" value="TFIIH_SSL1/p44"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002035">
        <property type="entry name" value="VWF_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036465">
        <property type="entry name" value="vWFA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00622">
        <property type="entry name" value="ssl1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12695">
        <property type="entry name" value="GENERAL TRANSCRIPTION FACTOR IIH SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12695:SF2">
        <property type="entry name" value="GENERAL TRANSCRIPTION FACTOR IIH SUBUNIT 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07975">
        <property type="entry name" value="C1_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04056">
        <property type="entry name" value="Ssl1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF015919">
        <property type="entry name" value="TFIIH_SSL1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01047">
        <property type="entry name" value="C1_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00327">
        <property type="entry name" value="VWA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57889">
        <property type="entry name" value="Cysteine-rich domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53300">
        <property type="entry name" value="vWA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50234">
        <property type="entry name" value="VWFA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0227">DNA damage</keyword>
    <keyword evidence="9" id="KW-0234">DNA repair</keyword>
    <keyword evidence="3 11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10 11" id="KW-0539">Nucleus</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 11" id="KW-0804">Transcription</keyword>
    <keyword evidence="7 11" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="6 11" id="KW-0862">Zinc</keyword>
    <keyword evidence="5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="VWFA" evidence="14">
        <location>
            <begin position="82"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C4-type" evidence="12">
        <location>
            <begin position="302"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="13">
        <location>
            <begin position="9"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006092"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRNR" id="PIRNR015919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR015919-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="OBZ83733.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="413" mass="45964" checksum="0A9994F41278C33B" modified="2016-11-30" version="1">MGPAKQADEDYIDVDDTYDGNQDDDHGNGGYAWEEEYKRSWDILQEDAEGRLSSVVSQLQQQRKRRRLLKDTAIIQRGIIRHLFLVIDLSEAMNEKDLRPSRVELTLTYAQQFVVEFFDQNPISQLGIIITRDGIAEKLTELSGNPTDHIKAIKLKKNTETSGEPSLQNALQLARASMLGVPSHGSKEVLLLFGSLTTCDPADIHETVQLLKKEMVRVNIVGLAAEVQICRLLAETTKGTYGVVLNEAHYKDLLFEVIPPPAVLPNKNTSNLVMMGFPKRLIEEHPTFCVCHSKLTLGGYICPKCKSKICELPSDCDICGLTLVSSPHLARSYHHLFPVHNFDEVKNNGGHALHCFSCLTQFDKQETSGGKFSCPKCQQEFCSECDIFVHEVLHNCPGCWSVGKKAAVVNGAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N426</accession>
    <name>A0A1C7N426_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">DUF300-domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">A0J61_08078</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000591">
        <property type="protein sequence ID" value="OBZ83872.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N426"/>
    <dbReference type="FunCoup" id="A0A1C7N426">
        <property type="interactions" value="191"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N426"/>
    <dbReference type="InParanoid" id="A0A1C7N426"/>
    <dbReference type="OrthoDB" id="5348404at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005178">
        <property type="entry name" value="Ostalpha/TMEM184C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23423">
        <property type="entry name" value="ORGANIC SOLUTE TRANSPORTER-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03619">
        <property type="entry name" value="Solute_trans_a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01417">
        <property type="entry name" value="Solute_trans_a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="20"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="59"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="92"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="156"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="186"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="231"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="477"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="511"/>
            <end position="606"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="483"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="522"/>
            <end position="538"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="539"/>
            <end position="548"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="559"/>
            <end position="572"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="584"/>
            <end position="593"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OBZ83872.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="606" mass="69422" checksum="01C6454A05E00320" modified="2016-11-30" version="1" fragment="single">RMASHQMESNYGDGGAGSTFYPVTIWIALVSTVIGCCISFLSVWLHWKNYRKPNQQRQVIRILWMVPIYGISTYISLVSLDAAFYVDTFRDIYEAFVIYAFFNLLLNKLGGERALIIMLHSRPPTQNFFPGTLYSRDIFVGDPYTFLFVKRGILQFVYVKPVLAVITMLLKATGNYNEGEFTLTSSYFYLTFIYNISVCLSLWCLMVFFYATKQDLAEFRPLPKFLCVKAIIFFSFWQGVAIALLVFAGIIPESEHISVAIQDFLVCLEMVPFAIGHAYSFSYTDYFDRIVHSARMPIRKAISDSFGIKDVLMDTLDTLQGDRFSYRSFEPSEGVPHIGSSRTSRIMAGLRYSNMTAKKHWLGPAPTSRFLNSSGRGMNEEVYIDDDHEPLEFEDPQSDDEMEKLYQASRKMMFGDYNYPVIDFREPILSQTHRHSQYGGLDQSMPFNQSKMDIGPREGCIDVIIQVERGKYVVNDDMHRKQSPPPTPPQPPLRNPTLTDVKRIREDIAKHRQSLASPRPSPSHSTPQQVTSRYPQPQSSVSSSLHTSSRFDHRPDMPQRSSSAQPPSTVIQPPSEDPPSWHWPQHESDRETPFSESDYIKNPWAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N4B4</accession>
    <name>A0A1C7N4B4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex</fullName>
            <ecNumber evidence="7">2.3.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">Dbt_0</name>
        <name evidence="11" type="ORF">A0J61_09799</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 7">
            <name>(R)-lipoate</name>
            <dbReference type="ChEBI" id="CHEBI:83088"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the 2-oxoacid dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.-" evidence="7"/>
    <dbReference type="EMBL" id="LUGH01000939">
        <property type="protein sequence ID" value="OBZ82154.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N4B4"/>
    <dbReference type="STRING" id="101091.A0A1C7N4B4"/>
    <dbReference type="InParanoid" id="A0A1C7N4B4"/>
    <dbReference type="OrthoDB" id="15567at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016407">
        <property type="term" value="F:acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031405">
        <property type="term" value="F:lipoic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045333">
        <property type="term" value="P:cellular respiration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd06849">
        <property type="entry name" value="lipoyl_domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.559.10:FF:000007">
        <property type="entry name" value="Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="4.10.320.10:FF:000002">
        <property type="entry name" value="Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.10">
        <property type="entry name" value="Chloramphenicol acetyltransferase-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.320.10">
        <property type="entry name" value="E3-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003016">
        <property type="entry name" value="2-oxoA_DH_lipoyl-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001078">
        <property type="entry name" value="2-oxoacid_DH_actylTfrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050743">
        <property type="entry name" value="2-oxoacid_DH_E2_comp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000089">
        <property type="entry name" value="Biotin_lipoyl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023213">
        <property type="entry name" value="CAT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036625">
        <property type="entry name" value="E3-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004167">
        <property type="entry name" value="PSBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011053">
        <property type="entry name" value="Single_hybrid_motif"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43178">
        <property type="entry name" value="DIHYDROLIPOAMIDE ACETYLTRANSFERASE COMPONENT OF PYRUVATE DEHYDROGENASE COMPLEX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43178:SF5">
        <property type="entry name" value="LIPOAMIDE ACYLTRANSFERASE COMPONENT OF BRANCHED-CHAIN ALPHA-KETO ACID DEHYDROGENASE COMPLEX, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00198">
        <property type="entry name" value="2-oxoacid_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00364">
        <property type="entry name" value="Biotin_lipoyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02817">
        <property type="entry name" value="E3_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52777">
        <property type="entry name" value="CoA-dependent acyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47005">
        <property type="entry name" value="Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51230">
        <property type="entry name" value="Single hybrid motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50968">
        <property type="entry name" value="BIOTINYL_LIPOYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00189">
        <property type="entry name" value="LIPOYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51826">
        <property type="entry name" value="PSBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7 11" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="4 7" id="KW-0450">Lipoyl</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7 11" id="KW-0808">Transferase</keyword>
    <keyword evidence="5" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="Lipoyl-binding" evidence="9">
        <location>
            <begin position="69"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="domain" description="Peripheral subunit-binding (PSBD)" evidence="10">
        <location>
            <begin position="194"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="147"/>
            <end position="176"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001938"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003423"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51826"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="OBZ82154.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="494" mass="54641" checksum="B87F34343D4581B6" modified="2016-11-30" version="1">MYSRSFRKISSFVSFPLKRTFLTPKYHYHLLGGRNFHSSFGLQAVKPFLLADIGEGITECEVIQWYVLFVLLSLSAVSSHISHYENTMSRFVEPGSSVNEFDKICEVQSDKASVEISSRFTGKILKLHYGLNDIAKVGSPLVDIETEDEEGQDSVVAESSTNRRSEEASVQLKTQKQAEVPQISNIDQKNESVLATPAVRKLAKEKGIDISVVKGTGEEGRILKEDILSHQSGAHPVIQSAPVTEKPSESISSSTKTLTSIQKAMYKSMTRSLDIPQLGYKDEIELDSTTKYRAALNQHIANHPDLYSFKKMTYLPIFVKCLSIALSHYPIMNAKLSGDLSDVNSIKIDYIDSHNIGIAMDTPQGLIVPNVKNVQEKTIFEIAAEIHRLSELGKASAIPLADLKGATITLSNIGTIGGSYANPVIISSEMAIVALGRMQRLPRFDEQDNVVPRQIMPVSWSADHRIIDGATIARFGNHWKKLIENPALLASELR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N4L4</accession>
    <name>A0A1C7N4L4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Translation initiation factor eIF2B subunit alpha</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">eIF2B GDP-GTP exchange factor subunit alpha</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="primary">GCN3</name>
        <name evidence="10" type="ORF">A0J61_07875</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="8">Component of the translation initiation factor 2B (eIF2B) complex which is a heterodecamer of two sets of five different subunits: alpha, beta, gamma, delta and epsilon. Subunits alpha, beta and delta comprise a regulatory subcomplex and subunits epsilon and gamma comprise a catalytic subcomplex. Within the complex, the hexameric regulatory complex resides at the center, with the two heterodimeric catalytic subcomplexes bound on opposite sides.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytosol</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the eIF-2B alpha/beta/delta subunits family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000559">
        <property type="protein sequence ID" value="OBZ84075.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N4L4"/>
    <dbReference type="FunCoup" id="A0A1C7N4L4">
        <property type="interactions" value="807"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N4L4"/>
    <dbReference type="InParanoid" id="A0A1C7N4L4"/>
    <dbReference type="OrthoDB" id="10249309at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005851">
        <property type="term" value="C:eukaryotic translation initiation factor 2B complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005085">
        <property type="term" value="F:guanyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002183">
        <property type="term" value="P:cytoplasmic translational initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:1904262">
        <property type="term" value="P:negative regulation of TORC1 signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:1903833">
        <property type="term" value="P:positive regulation of cellular response to amino acid starvation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:1900036">
        <property type="term" value="P:positive regulation of cellular response to heat"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045948">
        <property type="term" value="P:positive regulation of translational initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10470">
        <property type="entry name" value="Translation initiation factor eif-2b, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1070">
        <property type="entry name" value="Translation initiation factor eIF-2B, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051501">
        <property type="entry name" value="eIF2B_alpha/beta/delta"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042528">
        <property type="entry name" value="elF-2B_alpha_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000649">
        <property type="entry name" value="IF-2B-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042529">
        <property type="entry name" value="IF_2B-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037171">
        <property type="entry name" value="NagB/RpiA_transferase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45860">
        <property type="entry name" value="TRANSLATION INITIATION FACTOR EIF-2B SUBUNIT ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45860:SF1">
        <property type="entry name" value="TRANSLATION INITIATION FACTOR EIF-2B SUBUNIT ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01008">
        <property type="entry name" value="IF-2B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100950">
        <property type="entry name" value="NagB/RpiA/CoA transferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 10" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="5" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004514"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00044208"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00044236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00046432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU003814"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OBZ84075.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="337" mass="37019" checksum="16546B39E9F0283B" modified="2016-11-30" version="1">MSNTNTTYDVVSAYKASLSDTELSTPVAVFKALTEFVRHSTAPTMSEFMQTLEKAAQDIRQEPESMPSNNNKNQHKAAIAVLAGVDLFMRFVTRNSHDFSLSEEARSFEDFKENLLSRASLILDKASSARERTAEIGAQFVHDNAVVLVQGYSRVIMSVLSYAANVQNKRFKVYVTEGRPNSDGLQAVSALRENGIPCRAILDSAVGYIMDKVDMVFVGAEGVVENGGIINKIGTFQIALVANALNKPVYAVAESYKFVRVYPLNQYDIPSETPEIVTFTSRRKSFSTTSNAETMDELASSNPSVDYTPPQHITLLLTDLGVLTPSGVSDELIKLYV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N568</accession>
    <name>A0A1C7N568_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Splicing factor YJU2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">cwf16</name>
        <name evidence="10" type="ORF">A0J61_07712</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Part of the spliceosome which catalyzes two sequential transesterification reactions, first the excision of the non-coding intron from pre-mRNA and then the ligation of the coding exons to form the mature mRNA. Plays a role in stabilizing the structure of the spliceosome catalytic core and docking of the branch helix into the active site, producing 5'-exon and lariat intron-3'-intermediates.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Component of the spliceosome. Present in the activated B complex, the catalytically activated B* complex which catalyzes the branching, the catalytic step 1 C complex catalyzing the exon ligation, and the postcatalytic P complex containing the ligated exons (mRNA) and the excised lariat intron.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 8">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the CWC16 family. YJU2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000537">
        <property type="protein sequence ID" value="OBZ84240.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N568"/>
    <dbReference type="FunCoup" id="A0A1C7N568">
        <property type="interactions" value="427"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N568"/>
    <dbReference type="InParanoid" id="A0A1C7N568"/>
    <dbReference type="OrthoDB" id="674963at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071006">
        <property type="term" value="C:U2-type catalytic step 1 spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000349">
        <property type="term" value="P:generation of catalytic spliceosome for first transesterification step"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03226">
        <property type="entry name" value="YJU2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007590">
        <property type="entry name" value="Saf4/Yju2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043701">
        <property type="entry name" value="Yju2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12111">
        <property type="entry name" value="SPLICING FACTOR YJU2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12111:SF1">
        <property type="entry name" value="SPLICING FACTOR YJU2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04502">
        <property type="entry name" value="Saf4_Yju2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="6" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="7 8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0747">Spliceosome</keyword>
    <keyword evidence="5 8" id="KW-0862">Zinc</keyword>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="103"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="112"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="128"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="43"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="46"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="80"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="83"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OBZ84240.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="284" mass="32965" checksum="9EBB256CBADFD0B2" modified="2016-11-30" version="1">MSERKVLNKYFPPNFDPSQIPRQKKPKDLQHKVRLMTPFTMRCESCGEYINKGKKFNARKETAEGETYLSIKIYRFYIRCPRCSAEITFKTDPKNTDYVAEHGATRNFEPWRQTEDDKESSSEDEPEDPMKSLESRTLDSKREMDIMDALDEIRTRNARSERITVDEVLSRFSTEDKAVISERMKLEEEEDEKQAKAIFQSADGEQVRKIKEAEPEAIQLVSQQVKTELPSFKPAAILQRKRKQNTNSVVVVKKKKEDEKKVRSSLSLLANYQDISSSSSDSDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N5E8</accession>
    <name>A0A1C7N5E8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Pre-mRNA-splicing factor SYF1</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">Pre-mRNA-splicing factor syf1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="16" type="primary">syf1</name>
        <name evidence="16" type="ORF">A0J61_07698</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Involved in pre-mRNA splicing and cell cycle progression.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Associated with the spliceosome.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the crooked-neck family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000535">
        <property type="protein sequence ID" value="OBZ84251.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N5E8"/>
    <dbReference type="FunCoup" id="A0A1C7N5E8">
        <property type="interactions" value="844"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N5E8"/>
    <dbReference type="InParanoid" id="A0A1C7N5E8"/>
    <dbReference type="OrthoDB" id="10067343at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071014">
        <property type="term" value="C:post-mRNA release spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000974">
        <property type="term" value="C:Prp19 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071007">
        <property type="term" value="C:U2-type catalytic step 2 spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000349">
        <property type="term" value="P:generation of catalytic spliceosome for first transesterification step"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.10:FF:000023">
        <property type="entry name" value="Pre-mRNA-splicing factor SYF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.10:FF:000137">
        <property type="entry name" value="Pre-mRNA-splicing factor syf1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.10:FF:000038">
        <property type="entry name" value="Putative pre-mRNA-splicing factor SYF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003107">
        <property type="entry name" value="HAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055433">
        <property type="entry name" value="HAT_Syf1-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056350">
        <property type="entry name" value="HAT_Syf1_central"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055430">
        <property type="entry name" value="HAT_Syf1_CNRKL1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045075">
        <property type="entry name" value="Syf1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11246">
        <property type="entry name" value="PRE-MRNA SPLICING FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11246:SF5">
        <property type="entry name" value="PRE-MRNA-SPLICING FACTOR SYF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23231">
        <property type="entry name" value="HAT_Syf1_CNRKL1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23233">
        <property type="entry name" value="HAT_Syf1_CNRKL1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23220">
        <property type="entry name" value="HAT_Syf1_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00386">
        <property type="entry name" value="HAT"/>
        <property type="match status" value="12"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="7" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0747">Spliceosome</keyword>
    <keyword evidence="12" id="KW-0802">TPR repeat</keyword>
    <feature type="domain" description="Pre-mRNA-splicing factor Syf1-like N-terminal HAT-repeats" evidence="15">
        <location>
            <begin position="1"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="domain" description="Pre-mRNA-splicing factor SYF1 central HAT repeats" evidence="13">
        <location>
            <begin position="160"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="domain" description="Pre-mRNA-splicing factor Syf1/CRNKL1-like C-terminal HAT-repeats" evidence="14">
        <location>
            <begin position="371"/>
            <end position="724"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="12">
        <location>
            <begin position="379"/>
            <end position="412"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008644"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011524"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00037272"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00039472"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00067212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF23220"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF23231"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF23233"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="OBZ84251.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="727" mass="85801" checksum="D40FEC8D068778DF" modified="2016-11-30" version="1">MPYEEELLRSPFSIRTWIRYIDHKRNGSFSELCFVFERALKELPGSYKLWKQYLDFRRDKLKGLNAARHRQQYNAVIALYERALVLLNKMPRIWLDYLSLLTTMPVITKTRRSFDNALRALPVTQHTRIWDLYLQFAKAASGETALCIYRRYLKFEPTFVENFIENLIQLEYYDEAALKLVSIVNDTKFNSTKGKSHYQLWQQLCELVVEHCEAITSLQVESIIRSGIKRFTDQVGLLYSRLAMYWIKMGQLEKARDIFEEGITTVMTVRDFTVIFDAYAEFEEEMITTKMEMAAEREAAGEKDEEEDLDVDLRLLRFERLMDRRPFLVNDVLLRQNPNNVLEWQQRVLLWGDNKDKIVDTYTQAVQTINPKKAHGKLQELWAKFAKFYEDAGEIDSARAIFEKAIKVNYKSVNDLADIWCEYAEMETRHDAFDTAIEIMSRATQIPKTLDVNPKQVNFHDESIPVQQRLFKSLRLWSFYIDLEESVGTVESTKAVYDQVMDLRIANPQVIVNYATFLEENQYFEESFKVYERGIELFGWPIAFELWNIYLERFLKRYGGSKLERARDLFEQALNGCPPKYAKPIYLMYGKLEEEHGLARHAMRIYDRATSAVADDDRMEMYEYYIAKATESFGIMASREIYERAIEALPDKHVRIMSLRYAELERKLGEIDRARAIYGFASQLFNPRTEAGFWKTWHDFEVQHGNEDTFKEMLRIKRSVQATFPSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N5K1</accession>
    <name>A0A1C7N5K1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Chitin deacetylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">CDA_10</name>
        <name evidence="5" type="ORF">A0J61_09318</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000823">
        <property type="protein sequence ID" value="OBZ82634.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N5K1"/>
    <dbReference type="STRING" id="101091.A0A1C7N5K1"/>
    <dbReference type="InParanoid" id="A0A1C7N5K1"/>
    <dbReference type="OrthoDB" id="407355at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004099">
        <property type="term" value="F:chitin deacetylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009272">
        <property type="term" value="P:fungal-type cell wall biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd10952">
        <property type="entry name" value="CE4_MrCDA_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.370">
        <property type="entry name" value="Glycoside hydrolase/deacetylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011330">
        <property type="entry name" value="Glyco_hydro/deAcase_b/a-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002509">
        <property type="entry name" value="NODB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050248">
        <property type="entry name" value="Polysacc_deacetylase_ArnD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10587:SF133">
        <property type="entry name" value="CHITIN DEACETYLASE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10587">
        <property type="entry name" value="GLYCOSYL TRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01522">
        <property type="entry name" value="Polysacc_deac_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88713">
        <property type="entry name" value="Glycoside hydrolase/deacetylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51677">
        <property type="entry name" value="NODB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008889497" evidence="3">
        <location>
            <begin position="19"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="domain" description="NodB homology" evidence="4">
        <location>
            <begin position="92"/>
            <end position="281"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OBZ82634.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="381" mass="40076" checksum="24CC34B37D749D04" modified="2016-11-30" version="1">MKFISIAAVLSLISVIQAQNTTATTKESYPADGSKPVPKPEWLELIKNANITNAPVLKSQGSDGPSTSGPDNYCDWAKSGCVGTSIAACPKGMWGLTFDDGPSNVSPVLYDFLKTTNQKATLFMIGSNVIKYPQTVKRAYDEGHEIAIHTWTHSYMTTLTNEQIVAELKWTELAIKEIIGVSPRLFRPPYGDIDNRVRDIGTALGFTSVIWNHDTNDWMLAENYPGFKASYIDGNFTEWINEAKTASSGGLSLEHDILKPTVDAAIKNLPNLQKAYNVVTVGQCAGVSSYKESNATAPVNATSSAVSSAVSSAASTSSAALVSSSSTAVAAAVTSAAPSNAQNSAAAVAAGKSSMATSISSSNALLTSTIAAAFGIAFYMT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N5K2</accession>
    <name>A0A1C7N5K2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">U three protein 23</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">UTP23</name>
        <name evidence="10" type="ORF">A0J61_07538</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Involved in rRNA-processing and ribosome biogenesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the UTP23/FCF1 family. UTP23 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000514">
        <property type="protein sequence ID" value="OBZ84412.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N5K2"/>
    <dbReference type="FunCoup" id="A0A1C7N5K2">
        <property type="interactions" value="779"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N5K2"/>
    <dbReference type="InParanoid" id="A0A1C7N5K2"/>
    <dbReference type="OrthoDB" id="25675at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032040">
        <property type="term" value="C:small-subunit processome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd08553">
        <property type="entry name" value="PIN_Fcf1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1010:FF:000006">
        <property type="entry name" value="rRNA-processing protein UTP23 homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1010">
        <property type="entry name" value="5'-nuclease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006984">
        <property type="entry name" value="Fcf1/UTP23"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029060">
        <property type="entry name" value="PIN-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057776">
        <property type="entry name" value="UTP23_sensor"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12416">
        <property type="entry name" value="RRNA-PROCESSING PROTEIN UTP23 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04900">
        <property type="entry name" value="Fcf1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24779">
        <property type="entry name" value="UTP23_sensor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88723">
        <property type="entry name" value="PIN domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="3" id="KW-0698">rRNA processing</keyword>
    <feature type="domain" description="UTP23 sensor motif region" evidence="9">
        <location>
            <begin position="198"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="153"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="153"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="210"/>
            <end position="225"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00037300"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00038503"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00076388"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF24779"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OBZ84412.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="225" mass="25949" checksum="6E2032136EA6A3DA" modified="2016-11-30" version="1">MTKASRTNKKIVHSYCIGFGFRPPFQVVTDGEFCKKALEKKIYVKDAIPELVGEKVKIVVTECILKDIKDKGHDFTSALILAQKFDVRKCPHKEEKVSAYQCIRELVGTENKDHYFVASQNPKLRDRMRKVPGVPILYVNVKHQGLGLEPMTDRSKASFKSHEEQKMKPLDKDTARLKRKLIEEEQQKRKQEARPMAKKRKVKGVNPLAMKKKKKTPPPPKKNKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N5P0</accession>
    <name>A0A1C7N5P0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Nuclear speckle splicing regulatory protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">A0J61_07610</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the NSRP1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000523">
        <property type="protein sequence ID" value="OBZ84337.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N5P0"/>
    <dbReference type="FunCoup" id="A0A1C7N5P0">
        <property type="interactions" value="34"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N5P0"/>
    <dbReference type="InParanoid" id="A0A1C7N5P0"/>
    <dbReference type="OrthoDB" id="446635at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000381">
        <property type="term" value="P:regulation of alternative mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053246">
        <property type="entry name" value="NS_splicing_regulatory_protein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018612">
        <property type="entry name" value="NSRP1_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47845">
        <property type="entry name" value="NUCLEAR SPECKLE SPLICING REGULATORY PROTEIN 1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47845:SF1">
        <property type="entry name" value="NUCLEAR SPECKLE SPLICING REGULATORY PROTEIN 1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09745">
        <property type="entry name" value="NSRP1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nuclear speckle splicing regulatory protein 1 N-terminal" evidence="4">
        <location>
            <begin position="69"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="198"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="295"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="321"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="17"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="198"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="214"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="326"/>
            <end position="353"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF09745"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OBZ84337.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="371" mass="43761" checksum="BF4238732D8A3F72" modified="2016-11-30" version="1">MQQLKFGLNLQKKKTPITPQSRLTQRASAFAHESEDEEEEAPKENVKSAKAQVNRQLSGYNTMTKKLAEQQAKALEEDPTIFDYDAVYDDLKDVERKKQEKTKPKEKKAKYIQGLLEMAEIRKRDRVLAEEKKVAREREAEGDEFADREVFVTESFRKQKEELERIEREEKEREQLAEKNKTMDSFYKQVLERKEAEHQAMIKAMAERKKQRQSDNTSSTEQTETDIQLVEQAKREGKEVLLNDNNEIVDKRQLLGAGLNVKPKFGSLGSLAASDERIKERMDEYEAYKRKKVEDYQSRRRQGQSNDEREQVSKEVERQIMQVQQEKQEEEERKQKEFEQKVAAKRTTEDAVMSARERYLARKKQRLEGKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N5Q6</accession>
    <name>A0A1C7N5Q6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Homeobox domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">A0J61_07984</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000577">
        <property type="protein sequence ID" value="OBZ83966.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N5Q6"/>
    <dbReference type="STRING" id="101091.A0A1C7N5Q6"/>
    <dbReference type="InParanoid" id="A0A1C7N5Q6"/>
    <dbReference type="OrthoDB" id="2389483at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00086">
        <property type="entry name" value="homeodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001356">
        <property type="entry name" value="HD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00046">
        <property type="entry name" value="Homeodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00389">
        <property type="entry name" value="HOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50071">
        <property type="entry name" value="HOMEOBOX_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1 2" id="KW-0371">Homeobox</keyword>
    <keyword evidence="1 2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Homeobox" evidence="4">
        <location>
            <begin position="377"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="Homeobox" evidence="1">
        <location>
            <begin position="379"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="29"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="328"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="39"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="333"/>
            <end position="350"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU000682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OBZ83966.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="488" mass="56131" checksum="DD87F52D4E51517F" modified="2016-11-30" version="1">MYTDYQQLIMSNTHDSYVPDLTAYIKQELPQSPVPPTYPSSLSSSSPHTHLSDNDDSLAYALNEVYLEEMDAAEYQHPSAETILFFEILQEYPDLSSFIGHKDSMTFCHLWLKLQQAISSARQPQHRPRIQAWLKSAALQIHFLLVSIVKSNPGNNDMTSEPRCMFSAFRRLKDRIEIVHQVFQLIENGRVWFNQSPLEAIQPLVDAASQIKENMSYFSDRSNAIPVMGDTSDHVTMVNPDSVSLEDLSNHTIHTYNMMPYDAPLVQTSWSLPVTPSCADYRSFSSLPTSPTCAGAFHLTSGDHPSSFESDIYDWPSPIRSVSEAIGDLTTQVDEDDYVASETETEEEEENAKKKKRSNQPKASLTGRTRKERTERRYTRRTATSYDAQTTHYLKTVFFSIYSSREKLTKEQRRQVQKETGLKPRNITYWFSNHKRRFQTSLAVFKRVVDQSGGQVKTYDDFLAWRRQHGLPEEVSEEELEDDYHKTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N5U1</accession>
    <name>A0A1C7N5U1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Vacuolar iron transporter 1.1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">VIT1.1_0</name>
        <name evidence="7" type="ORF">A0J61_07939</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the CCC1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000569">
        <property type="protein sequence ID" value="OBZ84009.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N5U1"/>
    <dbReference type="FunCoup" id="A0A1C7N5U1">
        <property type="interactions" value="435"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N5U1"/>
    <dbReference type="InParanoid" id="A0A1C7N5U1"/>
    <dbReference type="OrthoDB" id="73465at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005384">
        <property type="term" value="F:manganese ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030026">
        <property type="term" value="P:intracellular manganese ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008217">
        <property type="entry name" value="Ccc1_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31851">
        <property type="entry name" value="FE(2+)/MN(2+) TRANSPORTER PCL1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01988">
        <property type="entry name" value="VIT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="151"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="180"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="211"/>
            <end position="234"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OBZ84009.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="243" mass="27162" checksum="D80B4CBA0A4BD668" modified="2016-11-30" version="1">MSALLNKLRRRPSHELPPYQHLEQHFESAEIVRDTIIGLSDGLTVPFALAAGLSSLGSSKLVIYGGAAGGYLAARSEIEHYRTERLREEFEVEECPQDEEEEIVEILEPYGLDRETIQPLINKLKSDPQKFVDFMMKFELNLEMPDPRRSWISALTIGLSYFIGGLIPLMPYFFIEEAMYALYVSVAVTSLTLLIFGYIKSRLVNPNSAMWGAVQTLLIGAVAAGASYGIVYLLPQEPNMGLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N6W4</accession>
    <name>A0A1C7N6W4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="18">White collar 1 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="18" type="primary">wc-1_2</name>
        <name evidence="18" type="ORF">A0J61_07621</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18 19">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000524">
        <property type="protein sequence ID" value="OBZ84329.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N6W4"/>
    <dbReference type="SMR" id="A0A1C7N6W4"/>
    <dbReference type="STRING" id="101091.A0A1C7N6W4"/>
    <dbReference type="InParanoid" id="A0A1C7N6W4"/>
    <dbReference type="OrthoDB" id="447251at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009881">
        <property type="term" value="F:photoreceptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.450.20:FF:000064">
        <property type="entry name" value="Vivid PAS protein VVD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.20">
        <property type="entry name" value="PAS domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001610">
        <property type="entry name" value="PAC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013655">
        <property type="entry name" value="PAS_fold_3"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00229">
        <property type="entry name" value="sensory_box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47429:SF7">
        <property type="entry name" value="GATA-FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47429">
        <property type="entry name" value="PROTEIN TWIN LOV 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08447">
        <property type="entry name" value="PAS_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13426">
        <property type="entry name" value="PAS_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00086">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00091">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="PYP-like sensor domain (PAS domain)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50112">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="12" id="KW-0010">Activator</keyword>
    <keyword evidence="9" id="KW-0157">Chromophore</keyword>
    <keyword evidence="15" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="11" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4" id="KW-0288">FMN</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1" id="KW-0600">Photoreceptor protein</keyword>
    <keyword evidence="14" id="KW-0675">Receptor</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0716">Sensory transduction</keyword>
    <keyword evidence="13" id="KW-0804">Transcription</keyword>
    <keyword evidence="10" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="8" id="KW-0862">Zinc</keyword>
    <keyword evidence="7" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="PAS" evidence="17">
        <location>
            <begin position="142"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="domain" description="PAS" evidence="17">
        <location>
            <begin position="389"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="42"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="85"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="304"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="15">
        <location>
            <begin position="696"/>
            <end position="723"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="16">
        <location>
            <begin position="63"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="16">
        <location>
            <begin position="312"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="16">
        <location>
            <begin position="337"/>
            <end position="356"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022543"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022606"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS50112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="OBZ84329.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="769" mass="86024" checksum="2A44422F8FDCBFDF" modified="2016-11-30" version="1">MDPFQSFPVQFNPQIYESSNVPPSTNRLFSISGFQAGLMTNQQPINTNGNAAPINMQRPMAHPSLSAQPSRPQPAAQPQRFLQPTTAPMVQPPPPDSQIENGSRYSGMYANTGFDMLSLLSRVVNRPNQQINLGPVDLSCSFVVVDAKQYDFPIVYVSPSFERLTDYAPHEVIGRNCRFLQAPDGRVAIGSRRKYTDNSTVYHIKTHMVQGKESQSSIINYRKTGQPFVNLLTVIPISWESSDEIDYFVGLQVDLVEQPNSIFQSMKDGTYSVNYRNSVIPSSISGMQMNPEFSGEAVEVWKRPTSPKPMAGSSSATSSAIPANNESMHMGLPMASENDNTSAPSSSTHNANTNIHRSSDPDPSMDVETLIKEASTDEGKYRRCWHELLLDQSPDFIHVLTIKGIFLYCSDSIQNVLEYEPSELIGKSLKDICHPSDITTVMRELKQSSSDSTEPVNLIYRVRRKNSGYMWIESCGKLRNEDGRGRKYVVLSGRERPVYQLPRNALTIGNKAHEIRTPADSLLPGTEDHEFWGKLSTDGLLLYASWTCANILGSPPSDIVGTSLYHRMRSNRTTDLTRALAEVKEGKIVYLRHALVNNADIEVMVATTFYPDGRKSLEDQPSFVLMQTKVIDDESALTDDEPIFVSMDPDVKKKGRADITLSNMSNNMGNNSIRSNAERMIDELDINRDANWQYELHQLRISNKKLRDDLAVLLQRAKQEGDEEVAHCNSCYRRLPGTSELSEFSIDEPLLCNTCSLRELPVPTLATQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N768</accession>
    <name>A0A1C7N768_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_07003</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000452">
        <property type="protein sequence ID" value="OBZ84942.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N768"/>
    <dbReference type="STRING" id="101091.A0A1C7N768"/>
    <dbReference type="InParanoid" id="A0A1C7N768"/>
    <dbReference type="OrthoDB" id="2289409at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="53"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="81"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="263"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ84942.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="263" mass="29431" checksum="D8ABB4C5A586D706" modified="2016-11-30" version="1" fragment="single">MDIDFDMNEISLCEDDIEAVPEIIVSVMSMMRKKWEYNITASAMELDEDATMELKEEYEGDEASNSSDKEENAADVQGSESDLKEEKPLRDLTEKKDAATNTRRVYTQQDINKLISLLIEQIPVKDAALKTGINEKSAYRFKSQWQKTGEIPQQKKRGRKMGTVSELTEKHTKFITDIVDECSTATVAGIHELLLKEFPTGFNLHMTRTRGWSKIGDPAKTTVPASKGTTITILGAISLRKPILVSGAKKRRIDGKVVTTTAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N7V7</accession>
    <name>A0A1C7N7V7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Tuberous sclerosis 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">tsc1</name>
        <name evidence="2" type="ORF">A0J61_06799</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000427">
        <property type="protein sequence ID" value="OBZ85161.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N7V7"/>
    <dbReference type="FunCoup" id="A0A1C7N7V7">
        <property type="interactions" value="1"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N7V7"/>
    <dbReference type="InParanoid" id="A0A1C7N7V7"/>
    <dbReference type="OrthoDB" id="6022054at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033596">
        <property type="term" value="C:TSC1-TSC2 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032007">
        <property type="term" value="P:negative regulation of TOR signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051726">
        <property type="term" value="P:regulation of cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007483">
        <property type="entry name" value="Hamartin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15154">
        <property type="entry name" value="HAMARTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15154:SF2">
        <property type="entry name" value="HAMARTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04388">
        <property type="entry name" value="Hamartin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="523"/>
            <end position="542"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="755"/>
            <end position="792"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="530"/>
            <end position="539"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="775"/>
            <end position="788"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ85161.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="827" mass="96689" checksum="E083B20B1CF0705A" modified="2016-11-30" version="1">MVSLRDIIKTTTQAVRTATAVSDGQAALDVIEQYVDEQTSADVGDVATVLAHIDPASVDRLSQELVQLYETTCHPESAMITCQPDRQNTQHIIILSSLRALLPILKPNKIFDDWWYLLQPILSLASYSNQVKKEARLIVSDALIMEQELMRQQHVECVYFHRLVDMYLGWAQSARTKQEEEITTQSHQVLLDLEQDEWSRNLTTILLSVGASETKSFFLLLNKYYLSSQHRLQIVYLLSEFMRRRRTHLHEILDTPLFESMLKSLMYDNSTTLIAISVTNLIMLLPRMCTSLPRFLPQLFYIFARAICWDQLRDVRQKQQTEYTRTVEDGWDCVDYTFSKLSAPPSNPQTGAFFTSLYGLYPCNFLQFLYKPYAYFKDKEFQVPEEFDEETFKTRTIPQVTRHMLHPNLVAMDAQIELTDKTRWMKMEPPDVIAQIMSLDLTNAASRVAFAHDDTEKTQPDLLDDALWDTDKKKKEEDIVEKKAPAPTMEPKPNVISHIVTLHKALKSGAEVLVDQDIWDPSSSTTPLIESEEQTEEAPDMSQETRLLVAALKREVLLLRNELNFELFLKQQHLQHIGRLHREHVLDTSVEAERQQLYNTTRLLKAQLNQTTLALEKLKAESALTKQKHIKWEDEQSVKLRNYREQRKEWQAQMTRTEHQVNDYQKQLDEQRVQLDHARQRIFELEHQLKTLEPILNSATENEHRVKQLTQQMLLWESNMSRMEEQKRYIKGLLSQWWSMEELIASLQSENKRLHEEQLQLQQQQQKKQEKEKSSINPNPFDSSSSSNKELTRLKETLTEFKSRLEALEMEKLEWQASKESVPNVCY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N824</accession>
    <name>A0A1C7N824_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Putative acyl-activating enzyme 1, peroxisomal</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">AAE1</name>
        <name evidence="7" type="ORF">A0J61_06845</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ATP-dependent AMP-binding enzyme family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000433">
        <property type="protein sequence ID" value="OBZ85108.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N824"/>
    <dbReference type="STRING" id="101091.A0A1C7N824"/>
    <dbReference type="InParanoid" id="A0A1C7N824"/>
    <dbReference type="OrthoDB" id="10253115at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006631">
        <property type="term" value="P:fatty acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.300.30:FF:000008">
        <property type="entry name" value="2,3-dihydroxybenzoate-AMP ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="entry name" value="N-terminal domain of ligase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025110">
        <property type="entry name" value="AMP-bd_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_synth/lig_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43859">
        <property type="entry name" value="ACYL-ACTIVATING ENZYME"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43859:SF4">
        <property type="entry name" value="BUTANOATE--COA LIGASE AAE1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13193">
        <property type="entry name" value="AMP-binding_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56801">
        <property type="entry name" value="Acetyl-CoA synthetase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="2" id="KW-0436">Ligase</keyword>
    <keyword evidence="4" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AMP-dependent synthetase/ligase" evidence="5">
        <location>
            <begin position="47"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="domain" description="AMP-binding enzyme C-terminal" evidence="6">
        <location>
            <begin position="461"/>
            <end position="536"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF13193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OBZ85108.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="536" mass="60155" checksum="7962F2FF48AA4637" modified="2016-11-30" version="1">MAKRLELLKHHLLPMQNPQFETLHIHRRPDQKPYLSKLDPLQFLLRSAMVYATNTAVIDGDRQLTYMDLAHRVRTLANVFISQYNIQQGERVGILCQNLIPNLEAQFAIPAIGAIMVPINTRLGMEEIEYIIQHAGISLLIVQSEWIERLSQTVLLSVKMIEVGHTASPYEQLLASHEPKLSWNDLPSVTDENETISINYTSGSTGRPKGVMATYRGLYMMAIGMLIHSKLSSDTRFLWTLPMFHCNGWGFPWAIVAVGGTQLMLDKMDYTKIWELLRHHNINHYNGAPTVQLEICNHKDASRLPHPVTVFSGGSVLSATLVKQMKALNLIPTQVYGLTETYGPAVTSYDHSLLRNYTEEEQFKLLARPGFNIITSDEVRILDKQGVDVKPDGNTIGEICFTGNLVMKGYYNAPEETEKAFRGGYFWTGDLGVRHPDGSIEIVDRIKDIIISGGENISSLEVENVLIQLDEVLECTVVAGPDDKWGERPVAFVVVKKGNVLDEKTVIEHCKKLLAGYKCPSKVIFTETIPRTSTGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N8P6</accession>
    <name>A0A1C7N8P6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">MICOS complex subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_06461</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Component of the mitochondrial contact site and cristae organizing system (MICOS) complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000390">
        <property type="protein sequence ID" value="OBZ85492.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N8P6"/>
    <dbReference type="STRING" id="101091.A0A1C7N8P6"/>
    <dbReference type="InParanoid" id="A0A1C7N8P6"/>
    <dbReference type="OrthoDB" id="2399148at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061617">
        <property type="term" value="C:MICOS complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044284">
        <property type="term" value="C:mitochondrial crista junction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042407">
        <property type="term" value="P:cristae formation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.20">
        <property type="entry name" value="Apolipoprotein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019166">
        <property type="entry name" value="MIC26/MIC27"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033181">
        <property type="entry name" value="Mic26_fungi"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28268">
        <property type="entry name" value="MICOS SUBUNIT MIC26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28268:SF1">
        <property type="entry name" value="MICOS SUBUNIT MIC26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09769">
        <property type="entry name" value="ApoO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF58113">
        <property type="entry name" value="Apolipoprotein A-I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="1" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU363021"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ85492.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="253" mass="28366" checksum="CFA007B336DC0EE9" modified="2016-11-30" version="1">MFSPILKRSFATAAASSAYLATATTAFAEEKRTKLSIYDQPEPKVVIIESPTKLEEQVFYAQKYANETLEEGKTHVNGFVQKYKEVEHQVTTEINNTIDKDEEIFPNAFYVGVAALAGTILARNRNIVLRFLTSTTLAVGTSYYLLPKTTHNVGLQLEKLERKYPQLQEAHQSVNAVVGDVRKQFDSTVSDVRGTFDQNVNKLQEQIQQNTASLKSAVNGSETKDKFDQVKKNVESMYSTRSNPGVEETLKKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N928</accession>
    <name>A0A1C7N928_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Vacuolar amino acid transporter 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">avt3_5</name>
        <name evidence="9" type="ORF">A0J61_06823</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the amino acid/polyamine transporter 2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000430">
        <property type="protein sequence ID" value="OBZ85126.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N928"/>
    <dbReference type="FunCoup" id="A0A1C7N928">
        <property type="interactions" value="82"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N928"/>
    <dbReference type="InParanoid" id="A0A1C7N928"/>
    <dbReference type="OrthoDB" id="1684102at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005774">
        <property type="term" value="C:vacuolar membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015179">
        <property type="term" value="F:L-amino acid transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013057">
        <property type="entry name" value="AA_transpt_TM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22950">
        <property type="entry name" value="AMINO ACID TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22950:SF666">
        <property type="entry name" value="VACUOLAR AMINO ACID TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01490">
        <property type="entry name" value="Aa_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="307"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="349"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="392"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="416"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="457"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="492"/>
            <end position="515"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="535"/>
            <end position="559"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="580"/>
            <end position="597"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="603"/>
            <end position="625"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="637"/>
            <end position="657"/>
        </location>
    </feature>
    <feature type="domain" description="Amino acid transporter transmembrane" evidence="8">
        <location>
            <begin position="275"/>
            <end position="657"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="105"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="169"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="241"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="40"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="107"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="241"/>
            <end position="257"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008066"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OBZ85126.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="677" mass="74371" checksum="A61D6DD45531DAD7" modified="2016-11-30" version="1">MSSPLPVNAKRANQAGDGSRIPRVDESLLSSSFDHAESTARLSSSPMPPSNFGTSPSRSILSSHLNNYGTGDNISSSRPHSTFGDNLSVDLPDEEVAKAVRRHLVSASPSNSSHGYLNTPSPHRSRSGSRLSNHRSNNESDEEEDEIADVHRLPGGAITHDIYKWSEDQDRKARMKRSKSLMVARSEPSDPALQNLRDPGGFRRHFVFDRAAKKGRKPPGWITHSFVDFLTLYGHFGGEDLSDDEGESSDDEEEDLEGSPNERTSLLPEQRSEGTATPTKAVFLLLKSFIGTGVMFLPKAFHNGGLLFSTLFLSFIAAVSLYCFLLLVETRNKVPYSFGDIGGKLFGNSMRMLVLVAITTSQIGFVCAYMVFVAQNLQALIEAISNCKTNIPLHYLILVQIAVFVPLAMIRKIQKLSVFALIADAFILIGLSYLYYYDFLTLALEGVANVEWIVNPASFPMFIGTAVFTFEGVGLIIPITESMKDPKKFPKVLSGTMLFITLLFISIGLLSYLAFGDDVQTVILLNLPVSPVVNTIQGLYAMAICLSIPLQLFPAIRIVETGLFSKSGKNNPVVKWQKNMFRFASVLVSAGVAIVGSSDLDKFVSLIGSVFCIPLCFLFPPLFHYKAVATNWKHKTIDVAIIAFGLATMAYTTYITVELWTQENEPPAPISRCTPHV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N988</accession>
    <name>A0A1C7N988_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="14">Putative Na(+)/H(+) antiporter C3A11.09</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">sod22_0</name>
        <name evidence="14" type="ORF">A0J61_06777</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the fungal Na(+)/H(+) exchanger family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000425">
        <property type="protein sequence ID" value="OBZ85176.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N988"/>
    <dbReference type="FunCoup" id="A0A1C7N988">
        <property type="interactions" value="107"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N988"/>
    <dbReference type="InParanoid" id="A0A1C7N988"/>
    <dbReference type="OrthoDB" id="2190219at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015385">
        <property type="term" value="F:sodium:proton antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0120029">
        <property type="term" value="P:proton export across plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042391">
        <property type="term" value="P:regulation of membrane potential"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036376">
        <property type="term" value="P:sodium ion export across plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1530.20:FF:000015">
        <property type="entry name" value="Na(+)/H(+) antiporter 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006153">
        <property type="entry name" value="Cation/H_exchanger_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004712">
        <property type="entry name" value="Na+/H+_antiporter_fungi"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31382">
        <property type="entry name" value="NA(+)/H(+) ANTIPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31382:SF1">
        <property type="entry name" value="SODIUM ION_PROTON EXCHANGER (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00999">
        <property type="entry name" value="Na_H_Exchanger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0050">Antiport</keyword>
    <keyword evidence="8" id="KW-0406">Ion transport</keyword>
    <keyword evidence="9 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0915">Sodium</keyword>
    <keyword evidence="10" id="KW-0739">Sodium transport</keyword>
    <keyword evidence="5 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="6"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="36"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="66"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="97"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="198"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="240"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="320"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="355"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="395"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="domain" description="Cation/H+ exchanger transmembrane" evidence="13">
        <location>
            <begin position="19"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="448"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="451"/>
            <end position="466"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022449"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF00999"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="OBZ85176.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="493" mass="54501" checksum="4AC0B9EC5DB93E9E" modified="2016-11-30" version="1">MAVETISVVIFILGGFILLFGLTSLIIKEKLYVSEAFVAILCGIIFGPVCSDFIKVETWGNTEQITKQFCRLVIAIQVMAAGVALPKAYLRRELRSLLIMLGPVMIYMWLVSGLLVWAIIPGLNFLEALMIAACFTPTDPVLANSIVQGKFAEKKVPSHVRDLISCESGANDGLGYPFLFFAVYLLQMETGSAIGKWAYWIMAYNVLLSVVIGFAVGYIARKLLKFAELKRFIDQESFLVFAIALALFLTGGVGLIGSDDLLACFVAGNSLTWDDWFRTETEQAHLMEVVDMLLNLSIFVFIGATIPWSSFADTSIQITLWRLFVLAILVLLLRRLPIILALYRYISAIKNWREAVFTGWFGPIGVGAIFYYTAALEAIPADGPNAHARSVIQPVVYFLVIASVVAHGVTIPLFYVGKFAKRTLTRTSEKTPIRVPVSNPTTIYSPELPISTTETLSTDTSEKSSTVESEPRKHTAIQILTPEKPEIAMDHKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N9D7</accession>
    <name>A0A1C7N9D7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Putative long-chain-alcohol O-fatty-acyltransferase 10</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">A0J61_06262</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="2">Secondary metabolite biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the wax synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000370">
        <property type="protein sequence ID" value="OBZ85691.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N9D7"/>
    <dbReference type="InParanoid" id="A0A1C7N9D7"/>
    <dbReference type="OrthoDB" id="1077582at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008374">
        <property type="term" value="F:O-acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044851">
        <property type="entry name" value="Wax_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032805">
        <property type="entry name" value="Wax_synthase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31595">
        <property type="entry name" value="LONG-CHAIN-ALCOHOL O-FATTY-ACYLTRANSFERASE 3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31595:SF57">
        <property type="entry name" value="OS04G0481900 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13813">
        <property type="entry name" value="MBOAT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0808">Transferase</keyword>
    <keyword evidence="5 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="93"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="177"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="209"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="240"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="domain" description="Wax synthase" evidence="9">
        <location>
            <begin position="124"/>
            <end position="217"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF13813"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OBZ85691.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="278" mass="32221" checksum="4C0C0B678A275CDD" modified="2016-11-30" version="1">MLQPWIYAIQMFFLTEAGVSLKEWIPMMIRIGTFQDETPNNLSSNDVRFGGIKKLVRGIAKLVFMRLVLDRFLPKDLSVILRYPFYDPNAMFLTYILAMRIYCMMSIVDVLMGLLQILFLVRFQDLFDNPFMSLSPKDFWNRRWNRAVRSMFNRFIFSKAVTSKKKKELKGKSKGQLPFLSSPLICGLAVFFISGVFHDFMVGAATRVITLEMTAFFMIHGFAVALEVILTKKIQLPNSLVLRIVCRVLTTIFFITTGRLFLSPILRSEIFLRLASRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N9P5</accession>
    <name>A0A1C7N9P5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">NodB homology domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">A0J61_06098</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Co(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:48828"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000352">
        <property type="protein sequence ID" value="OBZ85852.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N9P5"/>
    <dbReference type="STRING" id="101091.A0A1C7N9P5"/>
    <dbReference type="InParanoid" id="A0A1C7N9P5"/>
    <dbReference type="OrthoDB" id="407355at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016810">
        <property type="term" value="F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.50.10">
        <property type="entry name" value="Erythroid Transcription Factor GATA-1, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.370">
        <property type="entry name" value="Glycoside hydrolase/deacetylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011330">
        <property type="entry name" value="Glyco_hydro/deAcase_b/a-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002509">
        <property type="entry name" value="NODB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013088">
        <property type="entry name" value="Znf_NHR/GATA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001965">
        <property type="entry name" value="Znf_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019787">
        <property type="entry name" value="Znf_PHD-finger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46471">
        <property type="entry name" value="CHITIN DEACETYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46471:SF2">
        <property type="entry name" value="CHITIN DEACETYLASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01522">
        <property type="entry name" value="Polysacc_deac_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00249">
        <property type="entry name" value="PHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88713">
        <property type="entry name" value="Glycoside hydrolase/deacetylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51677">
        <property type="entry name" value="NODB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50016">
        <property type="entry name" value="ZF_PHD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 8" id="KW-0863">Zinc-finger</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="573"/>
            <end position="600"/>
        </location>
    </feature>
    <feature type="domain" description="PHD-type" evidence="11">
        <location>
            <begin position="213"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="domain" description="NodB homology" evidence="12">
        <location>
            <begin position="315"/>
            <end position="506"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="534"/>
            <end position="560"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="OBZ85852.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="15">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="601" mass="67321" checksum="E7A47B15A5A61DEE" modified="2016-11-30" version="1">MNELVFLQQTFSWMFWAPLVKDDVFLVPPSNTVSSLHGKTLIADISLSTEVPTPCLSPVTSPSDLLYNSEPLFDGFLLMEHSFDDKDQGESLPLIVPKEEKVFSIEPSKTMLQQDNQLSRKRRAESNSLSKKRVKSSNMTLFENLTASGIDWCRYCGTTEGVNWRPGPWGKRTLCNKHGCDYKGYGLASRLPRLDLSDFVNESLKDRRRPVVQQYCIVCQSPGLLPENELIPCQGGCSRAYHQRCHSDAIDSNDSWYCKPQCRQNKEHKQVALFAFVGTVYAGGEGSLVLPIWNHPLDMHPGGPVPQATACASAGQIALTYNEGPSDVTAKVLNGLKAAQAKANFFVNATWLYTQQYAMILQRAYNDGHLIGMSYRIPGDTSEGLTDDQIKQDVTDNAKIIETLIGVAPKYVRLHYTFPEDTRLQNILRNMGYTLIGYNLDAADYNYKNDPEGISNLYRQIFEKQLETYDSKGSFISLQYDIPETGSWQAIYDVVRVINDSGYTMVRLDGCLNDMQPYKEKASSVRFISDKHSLGQPSYKSGQVAPEKPTSVGSQFRMAGHDTPKEDTEVIKMIALGSVVSVSSWSHFIVGMIALFCIWVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N9U8</accession>
    <name>A0A1C7N9U8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 6">3-methyl-2-oxobutanoate hydroxymethyltransferase</fullName>
            <ecNumber evidence="3 6">2.1.2.11</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">panB</name>
        <name evidence="8" type="ORF">A0J61_06055</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5 6">
            <text>(6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + 3-methyl-2-oxobutanoate + H2O = 2-dehydropantoate + (6S)-5,6,7,8-tetrahydrofolate</text>
            <dbReference type="Rhea" id="RHEA:11824"/>
            <dbReference type="ChEBI" id="CHEBI:11561"/>
            <dbReference type="ChEBI" id="CHEBI:11851"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15636"/>
            <dbReference type="ChEBI" id="CHEBI:57453"/>
            <dbReference type="EC" id="2.1.2.11"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 6">Cofactor biosynthesis; (R)-pantothenate biosynthesis; (R)-pantoate from 3-methyl-2-oxobutanoate: step 1/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the PanB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.2.11" evidence="3 6"/>
    <dbReference type="EMBL" id="LUGH01000348">
        <property type="protein sequence ID" value="OBZ85895.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N9U8"/>
    <dbReference type="FunCoup" id="A0A1C7N9U8">
        <property type="interactions" value="394"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N9U8"/>
    <dbReference type="InParanoid" id="A0A1C7N9U8"/>
    <dbReference type="OrthoDB" id="425211at2759"/>
    <dbReference type="UniPathway" id="UPA00028">
        <property type="reaction ID" value="UER00003"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003864">
        <property type="term" value="F:3-methyl-2-oxobutanoate hydroxymethyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015940">
        <property type="term" value="P:pantothenate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd06557">
        <property type="entry name" value="KPHMT-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.60:FF:000003">
        <property type="entry name" value="3-methyl-2-oxobutanoate hydroxymethyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.60">
        <property type="entry name" value="Phosphoenolpyruvate-binding domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00156">
        <property type="entry name" value="PanB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003700">
        <property type="entry name" value="Pantoate_hydroxy_MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015813">
        <property type="entry name" value="Pyrv/PenolPyrv_kinase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040442">
        <property type="entry name" value="Pyrv_kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00222">
        <property type="entry name" value="panB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF001452">
        <property type="entry name" value="PRK00311.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20881">
        <property type="entry name" value="3-METHYL-2-OXOBUTANOATE HYDROXYMETHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20881:SF0">
        <property type="entry name" value="3-METHYL-2-OXOBUTANOATE HYDROXYMETHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02548">
        <property type="entry name" value="Pantoate_transf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000388">
        <property type="entry name" value="Pantoate_hydroxy_MeTrfase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51621">
        <property type="entry name" value="Phosphoenolpyruvate/pyruvate domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="6" id="KW-0566">Pantothenate biosynthesis</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6 8" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00049172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU362100"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OBZ85895.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="320" mass="35250" checksum="9029675B4972EC60" modified="2016-11-30" version="1">MPKQNQTRDYSSRPVDNKSTQQRRPKVTIKTIQSMYRKKEPISMMTAQDYPSGLIVDQSGIDMCLVGDSLAMVSLGYDSTNPLTVEDMLHHCRAVARGAKAPFIVADLPYGSYEASPQDAVRVSLKFMKEGNCDAVKLEGGIEMSETIEKITRIGIPVLAHIGLTPQRQASLGGFRVQGKTAKQASGLLRDAFAVQKAGAFGVVLEAIPAEIAGYITDQLEIPTIGIGAGVECSGQVLVQNDALGLFDRFVPKFTKQYCNLNQIMTNALKEYHEEVKTRQFPAPQNTYPIDPVQLDKFFALEKERMGIHEEEEAKSIHAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N9X9</accession>
    <name>A0A1C7N9X9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Protein NLRC3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">NLRC3_0</name>
        <name evidence="4" type="ORF">A0J61_06199</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000363">
        <property type="protein sequence ID" value="OBZ85758.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N9X9"/>
    <dbReference type="STRING" id="101091.A0A1C7N9X9"/>
    <dbReference type="InParanoid" id="A0A1C7N9X9"/>
    <dbReference type="OrthoDB" id="120976at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052201">
        <property type="entry name" value="LRR-containing_regulator"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24111:SF0">
        <property type="entry name" value="LEUCINE-RICH REPEAT-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24111">
        <property type="entry name" value="LEUCINE-RICH REPEAT-CONTAINING PROTEIN 34"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00368">
        <property type="entry name" value="LRR_RI"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="517"/>
            <end position="536"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="582"/>
            <end position="643"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="517"/>
            <end position="535"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OBZ85758.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="652" mass="73623" checksum="1FDE29EBEC440564" modified="2016-11-30" version="1">MTNIQSTKSILRQTQDPQQPTSWFSKLNTDLNPTPRLGFFGSFRKSTEDRSIDDELKPTSIRRVRFPIQMTTEYVFKRDDLVSQKVSVVTEPIQIGSCAQLLTLYELICRQKQEPTLDKLVTTLIAQPEATSLTRLDLSNQPLDPSNMKPFCDLLSIDFGLRELVLDNCGLEDETIKILAHSLLDHDRITHLSLARSKITHHGFRYLAIYLKESTRLVSLDLSYTQPDKKSIQYLTAATIKQQTNAFTLILDGCPLKAVHLEVLASSIRKPDSTLRNLSMTGQHRLLNQQAALSIGIMLRDYDNDQLVGLSQLTLDGQEMDAYGIQYIAQALRRNRQLKSLSMRSCKIDAKSCHLLGEALKYNQHLQQLDIACNPLCQPQLEGINQLAQALNINLSLKSLCLAETNLSTEAMIVLAESLPQNKSLVRLDVAGNHAIQMAGFMALAASLQMNSTITYVDVHTLDNDHDMMMLHHQMLAKCTQNAQSKQQNSTQPPIQAVARLTLEERLAAAVTRGKTMPKEVAEDNTKKQKGKKDEEEQWIQQAITYTESLEQSDRAALDQSKRFQQFLCTKIPQLPDTSPHLELLLAVNDRLTTAIEQFKEKTEPLKETVSATFEIGDDDDDFDEKNDRLKELRDEFEAEEGAVFLKAKKQN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NA46</accession>
    <name>A0A1C7NA46_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Zinc finger protein C25B8.19c</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">A0J61_05980</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000341">
        <property type="protein sequence ID" value="OBZ85967.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NA46"/>
    <dbReference type="STRING" id="101091.A0A1C7NA46"/>
    <dbReference type="InParanoid" id="A0A1C7NA46"/>
    <dbReference type="OrthoDB" id="6077919at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:001102">
        <property type="entry name" value="Transcription factor IIIA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000478">
        <property type="entry name" value="Zinc finger protein 133"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23235">
        <property type="entry name" value="KRUEPPEL-LIKE TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23235:SF120">
        <property type="entry name" value="KRUPPEL-LIKE FACTOR 15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 7" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="9">
        <location>
            <begin position="199"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="9">
        <location>
            <begin position="227"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="166"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="177"/>
            <end position="194"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OBZ85967.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="266" mass="30134" checksum="7A17E32A8BAEA064" modified="2016-11-30" version="1">MISIYSDMNFMNNNSNNTSNNNHKNLFHQTLLDKPQQTSVDTYLPMSHYPTNHSIMSSTFPSPPPPPPPALVPSLIPSQHTQWNQYNTILSHSNYLPLQHHRPQLSGMPTINDVLPITSNETFNKGHYYHQRLCSTPNLLYSQSMYPLSAEMSLPDESNLFFMKNRTGKQNNRRTSVHTSRSSSPSEAGRSSSPVNKRYSCSVCHKRFTRPSSLTTHMYSHTGEKPFECTVEGCGRKFSVVSNLRRHAKIHNNSNISSSTAFTFSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NBC2</accession>
    <name>A0A1C7NBC2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">JmjC domain-containing protein 4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">jmjd4</name>
        <name evidence="2" type="ORF">A0J61_05566</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000303">
        <property type="protein sequence ID" value="OBZ86383.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NBC2"/>
    <dbReference type="FunCoup" id="A0A1C7NBC2">
        <property type="interactions" value="279"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NBC2"/>
    <dbReference type="InParanoid" id="A0A1C7NBC2"/>
    <dbReference type="OrthoDB" id="424465at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016706">
        <property type="term" value="F:2-oxoglutarate-dependent dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045905">
        <property type="term" value="P:positive regulation of translational termination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.650">
        <property type="entry name" value="Cupin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041667">
        <property type="entry name" value="Cupin_8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003347">
        <property type="entry name" value="JmjC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050910">
        <property type="entry name" value="JMJD6_ArgDemeth/LysHydrox"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12480:SF6">
        <property type="entry name" value="2-OXOGLUTARATE AND IRON-DEPENDENT OXYGENASE JMJD4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12480">
        <property type="entry name" value="ARGININE DEMETHYLASE AND LYSYL-HYDROXYLASE JMJD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13621">
        <property type="entry name" value="Cupin_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00558">
        <property type="entry name" value="JmjC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51184">
        <property type="entry name" value="JMJC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="JmjC" evidence="1">
        <location>
            <begin position="122"/>
            <end position="277"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ86383.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="388" mass="45884" checksum="5132C0A834D91CA2" modified="2016-11-30" version="1">MDPDIPYYEIPPTYKEFLENHLIPNKPAIIGPSLIQDWKARKEWIVPVSEKTDSNQLFPKFKPNYAYLREHYGRAEGQVAKCDRRHFTDQERISMTFSEFVDLWEQDDGKESVYYLKDLHLVQLFPNDIAYTVPTLFEDDWLNEYWLEKGDDDYRFTYLGGHNTFTPFHADVYRSYSWSSNICGIKKWTFFPPGQEELFKNKFGNIIYDIREADSVEFPGLEQAYRIEIYQRDGETVFVPSGWFHQVENIGSTISINHNWSNACNLMLTYHSLHLDLKDVQVAIEDLKETMSNSEFADQCQQLLLVHSGWDWATFLNILYTVVMNRLNCRPKTCQPALSWQLDKIEDVIEKWEADEGKELIDYFERHDLFKTYMKLKSTISTIRATIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NC37</accession>
    <name>A0A1C7NC37_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Putative magnesium transporter NIPA8</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">A0J61_05260</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000280">
        <property type="protein sequence ID" value="OBZ86687.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="InParanoid" id="A0A1C7NC37"/>
    <dbReference type="OrthoDB" id="165382at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015095">
        <property type="term" value="F:magnesium ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008521">
        <property type="entry name" value="Mg_trans_NIPA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12570">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12570:SF82">
        <property type="entry name" value="NIPA-LIKE PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05653">
        <property type="entry name" value="Mg_trans_NIPA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="6"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="54"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="80"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="109"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="151"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="200"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="245"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="272"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="299"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="374"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="427"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="428"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="448"/>
            <end position="459"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OBZ86687.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="459" mass="50743" checksum="BC2944D565299D66" modified="2016-11-30" version="1">MGTEDNVIRFVIGVFVSLGASFMDALGLNILKVDHVKESKRSQDQQRGDCGRPLWHLGLYTYIASQLIGSTIAXSKVHDWVAPLGSVALIFNFIFAKLLVNTKITRKDVLGTCVVIASVIWIVVFGGMYNGEDPEQSISVDRLKVLFVRPIFIFYFSALNIIAFGGLFISIWSNWAISDESRRTKSQIFSGMNQKKMKRVVGLMFSTEGGVLASETLLLAKSGVKLFTLSVSSQVNQFNDNASRFILLALLVTAILQVYCLNTALKLYSSVVVVPVFYGTYTALGLVNTIIYLDEISNYPPWAIALVFIGIGVLIYGVFLLSSKPDPTSHLQDNLTSTTLPPPSSSSSAHQQELDVFADLKWLSAKEEKDVVSNKERELPKLAVNNAGESSNSHVNKKEENNRMSKFFRRFRVLHFQPRSSPFVSLYSSVDSHPSSNPSLVPDPSLDTVLSPSSDRVKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NC43</accession>
    <name>A0A1C7NC43_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_05274</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000281">
        <property type="protein sequence ID" value="OBZ86665.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NC43"/>
    <dbReference type="InParanoid" id="A0A1C7NC43"/>
    <dbReference type="OrthoDB" id="2449831at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008889609" evidence="1">
        <location>
            <begin position="17"/>
            <end position="209"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ86665.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="209" mass="22566" checksum="022199E31E21BEE4" modified="2016-11-30" version="1">MKSSFLILSAIATAHAALVLPPYPNPYESVRNYGCRHHSSSVEHYTGDYTSYTRTASWYSEHDCSEYASSPPYGYPTPYPYPIPFPGPIIEPIPIDPVIDPVPIDPVIDPIHGGVQPIPDEGVACIALYYPCPELCPDNCVRPTNSPCPFATRPTCPPEVCAAVLCAADPVKPCPADCLYGCDYINQSNPCCDFLGEPVCRGSPTIGIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NC72</accession>
    <name>A0A1C7NC72_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">RNA helicase</fullName>
            <ecNumber evidence="2">3.6.4.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="primary">ROK1</name>
        <name evidence="15" type="ORF">A0J61_05253</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10 17">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.13"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the DEAD box helicase family. DDX52/ROK1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.13" evidence="2"/>
    <dbReference type="EMBL" id="LUGH01000279">
        <property type="protein sequence ID" value="OBZ86695.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NC72"/>
    <dbReference type="FunCoup" id="A0A1C7NC72">
        <property type="interactions" value="658"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NC72"/>
    <dbReference type="InParanoid" id="A0A1C7NC72"/>
    <dbReference type="OrthoDB" id="360161at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032040">
        <property type="term" value="C:small-subunit processome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000480">
        <property type="term" value="P:endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000447">
        <property type="term" value="P:endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000472">
        <property type="term" value="P:endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048254">
        <property type="term" value="P:snoRNA localization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd17957">
        <property type="entry name" value="DEADc_DDX52"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18787">
        <property type="entry name" value="SF2_C_DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000759">
        <property type="entry name" value="probable ATP-dependent RNA helicase DDX52"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044764">
        <property type="entry name" value="DDX52/Rok1_DEADc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050079">
        <property type="entry name" value="DEAD_box_RNA_helicase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000629">
        <property type="entry name" value="RNA-helicase_DEAD-box_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47959">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE RHLE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47959:SF15">
        <property type="entry name" value="RNA HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00039">
        <property type="entry name" value="DEAD_ATP_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 11 15" id="KW-0347">Helicase</keyword>
    <keyword evidence="4 11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="13">
        <location>
            <begin position="156"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="14">
        <location>
            <begin position="357"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="506"/>
            <end position="564"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="506"/>
            <end position="550"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00024355"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00047984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU000492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="OBZ86695.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="564" mass="64116" checksum="266B8A2FFB4977BF" modified="2016-11-30" version="1">MDIFRLLGGGARFDKKRFQHDVNLFESEKEAIRTHIKQKNAAVNDPAVRDQLLQEIDFFNNTTTTDAEDQQNVMTKETSKKLKKAKKASSTIFDTVEEAKAFRKQQKIKVYGTDVPNPFRSFEDLASPAYNLSTTLYNNLMTVKYKTPTPVQMQSIPIMLNGRDLMSCAPTGSGKTMAYLLPILHDLKKPEKKSSYRALIIAPTRELIQQIAREANHLSQGTKLRVHVLTNPTSDEEKEEQKFDILITTPLRLVYAIKEKEVDLSAVKHLVLDEADKLLDQGFLEQTDEIFAACSSNNIQKSLFSATFSSHVEELAKTVMKDPIRIVIGAKNAATDTIRQELLFTGSESGKMIALRQLIQQGIKPPVLIFVQSIERAKELFHELVFDGLNVDVIHSDRTKAQRDHIIDQFRLGKIWVLIATELMARGLDFKGVNLVINYDFPQTVASYIHRIGRTGRAGRSGEAVTYYTKDDIPYMKGVVNVMKESGCQVPEWMLKLKNATHQQKRELKKGLDRTQIDSTSKYDKYQQKKKKEMIEASKKRKRAGSDKQSKKAKKQEEAEEKEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NCK9</accession>
    <name>A0A1C7NCK9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_05083</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000265">
        <property type="protein sequence ID" value="OBZ86862.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NCK9"/>
    <dbReference type="InParanoid" id="A0A1C7NCK9"/>
    <dbReference type="OrthoDB" id="5277092at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ86862.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="91" mass="10751" checksum="BF0C6DBAA31780CF" modified="2016-11-30" version="1">MSSSDNETNNNQNLIEKELDRLDKFVKDAPGNEYTIDQKEQELCRNFSGGQEQCIKLHLEYTQMFSKMQELGFFCQLPMDPTKTYMECRRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NCR2</accession>
    <name>A0A1C7NCR2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Coatomer subunit epsilon</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">Cope</name>
        <name evidence="12" type="ORF">A0J61_06795</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. The coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasmic vesicle</location>
            <location evidence="2">COPI-coated vesicle membrane</location>
            <topology evidence="2">Peripheral membrane protein</topology>
            <orientation evidence="2">Cytoplasmic side</orientation>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Golgi apparatus membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
            <orientation evidence="1">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 11">Belongs to the COPE family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000427">
        <property type="protein sequence ID" value="OBZ85154.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NCR2"/>
    <dbReference type="FunCoup" id="A0A1C7NCR2">
        <property type="interactions" value="335"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NCR2"/>
    <dbReference type="InParanoid" id="A0A1C7NCR2"/>
    <dbReference type="OrthoDB" id="310217at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030126">
        <property type="term" value="C:COPI vesicle coat"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005198">
        <property type="term" value="F:structural molecule activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006888">
        <property type="term" value="P:endoplasmic reticulum to Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006891">
        <property type="term" value="P:intra-Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006890">
        <property type="term" value="P:retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006822">
        <property type="entry name" value="Coatomer_esu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10805">
        <property type="entry name" value="COATOMER SUBUNIT EPSILON"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10805:SF0">
        <property type="entry name" value="COATOMER SUBUNIT EPSILON"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04733">
        <property type="entry name" value="Coatomer_E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016478">
        <property type="entry name" value="Coatomer_esu"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 11" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="10 11" id="KW-0968">Cytoplasmic vesicle</keyword>
    <keyword evidence="6 11" id="KW-0931">ER-Golgi transport</keyword>
    <keyword evidence="8 11" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="9 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 11" id="KW-0653">Protein transport</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 11" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRNR" id="PIRNR016478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="OBZ85154.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="301" mass="33385" checksum="DF562F69B4A534BD" modified="2016-11-30" version="1">MDEDSILFGIRNLFSVGNYQTVINEVSSSRGLFSTEAKLEAQTFLYRSYVAQGKYNLVINDIGSAEEAPLKAIKLLAEYLSSKGNAADYVTKANALLEEGANRIHPVVQVTIATLLVHAGHLEDALRTLHSRQKKLECSALAVQIYLLMDRLDLARNEVASVKTWAEDALLLQMMEAWVDLRVGGEKYQEAFYIYEEFGQSSTAQTVKVLNGQAAANLTLGRYPEAESLLLEAQNKDSNDPDTIINMIACAILTAKPQDVVNRYVSQLKEVAPEHPYIKDLDLKSSLFDRCASRYALVESA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NDI7</accession>
    <name>A0A1C7NDI7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 6">DNA replication complex GINS protein PSF1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">PSF1</name>
        <name evidence="9" type="ORF">A0J61_04799</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Required for correct functioning of the GINS complex, a complex that plays an essential role in the initiation of DNA replication, and progression of DNA replication forks. GINS complex seems to bind preferentially to single-stranded DNA.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Component of the GINS complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the GINS1/PSF1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000242">
        <property type="protein sequence ID" value="OBZ87162.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NDI7"/>
    <dbReference type="FunCoup" id="A0A1C7NDI7">
        <property type="interactions" value="213"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NDI7"/>
    <dbReference type="InParanoid" id="A0A1C7NDI7"/>
    <dbReference type="OrthoDB" id="10252587at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071162">
        <property type="term" value="C:CMG complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000811">
        <property type="term" value="C:GINS complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043596">
        <property type="term" value="C:nuclear replication fork"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902983">
        <property type="term" value="P:DNA strand elongation involved in mitotic DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000727">
        <property type="term" value="P:double-strand break repair via break-induced replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902975">
        <property type="term" value="P:mitotic DNA replication initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd11710">
        <property type="entry name" value="GINS_A_psf1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd21696">
        <property type="entry name" value="GINS_B_Psf1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.1030">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021151">
        <property type="entry name" value="GINS_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036224">
        <property type="entry name" value="GINS_bundle-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005339">
        <property type="entry name" value="GINS_Psf1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056783">
        <property type="entry name" value="PSF1_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12914:SF2">
        <property type="entry name" value="DNA REPLICATION COMPLEX GINS PROTEIN PSF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12914">
        <property type="entry name" value="PARTNER OF SLD5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24997">
        <property type="entry name" value="PSF1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05916">
        <property type="entry name" value="Sld5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF158573">
        <property type="entry name" value="GINS helical bundle-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0235">DNA replication</keyword>
    <keyword evidence="5 6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GINS subunit" evidence="7">
        <location>
            <begin position="46"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="domain" description="DNA replication complex GINS protein PSF1 C-terminal" evidence="8">
        <location>
            <begin position="156"/>
            <end position="203"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00015143"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU368085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF05916"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF24997"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OBZ87162.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="204" mass="23057" checksum="49EDD1F3836036AC" modified="2016-11-30" version="1">MAALGESAYKLAKEAKRTADLFISNYNDDLVQSICREIRLLNNKAIETVNAIKQDNSGDALQNPSTMTQVMLYHLAVKRNKRVLFAYHRQRINKLKDILWNVGLQSKYRREILTSLGPTEKSFLDEYGDIVNAYKQGFAEVDLGGMNGPGLDPPVDLFIEVRVLRDAGEINTEYGTLNLSKGNQFYVRRTDVESLIKAGYLVHV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NEI1</accession>
    <name>A0A1C7NEI1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">E3 ubiquitin-protein ligase RING1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">RING1</name>
        <name evidence="6" type="ORF">A0J61_04427</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000216">
        <property type="protein sequence ID" value="OBZ87523.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NEI1"/>
    <dbReference type="STRING" id="101091.A0A1C7NEI1"/>
    <dbReference type="InParanoid" id="A0A1C7NEI1"/>
    <dbReference type="OrthoDB" id="2257726at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006511">
        <property type="term" value="P:ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd16454">
        <property type="entry name" value="RING-H2_PA-TM-RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051834">
        <property type="entry name" value="RING_finger_E3_ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45931:SF3">
        <property type="entry name" value="RING ZINC FINGER-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45931">
        <property type="entry name" value="SI:CH211-59O9.10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13639">
        <property type="entry name" value="zf-RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="5">
        <location>
            <begin position="276"/>
            <end position="317"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OBZ87523.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="336" mass="38955" checksum="623B9A0CB4D11A06" modified="2016-11-30" version="1">MRFGSCIYCHRVIAIVNGTRVCGSCYILDQRDLVQEESEEDDEEEEEEEELEYLSEYEDMSDSENYVNEISQFFEQRWYDHISRANQLHREWIDDDTDGELDFAYQGMDSGDEVFIDHQEEDSGDEAFVGYREGDSDAYEGPPLLELPDDDSIELTSVYDEVPNDYEESDAYDSEGPPAIYSLDFSDEENEDETLSNIVEESLGVYFERLYSIRERLRQNNDYTTETLIQQLLHIYVANGTHESNTKGATESQMAALKRRTLTQQELSDGYSSNECTICTETYDEKLELTELPCSHEYHSVCIRQWLRINSNCPICRQTLAVSISNHSVEFMDDVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NEI2</accession>
    <name>A0A1C7NEI2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">deoxyribose-phosphate aldolase</fullName>
            <ecNumber evidence="2">4.1.2.4</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">2-deoxy-D-ribose 5-phosphate aldolase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">deoC</name>
        <name evidence="9" type="ORF">A0J61_04602</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>2-deoxy-D-ribose 5-phosphate = D-glyceraldehyde 3-phosphate + acetaldehyde</text>
            <dbReference type="Rhea" id="RHEA:12821"/>
            <dbReference type="ChEBI" id="CHEBI:15343"/>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
            <dbReference type="ChEBI" id="CHEBI:62877"/>
            <dbReference type="EC" id="4.1.2.4"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.1.2.4" evidence="2"/>
    <dbReference type="EMBL" id="LUGH01000228">
        <property type="protein sequence ID" value="OBZ87360.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NEI2"/>
    <dbReference type="STRING" id="101091.A0A1C7NEI2"/>
    <dbReference type="InParanoid" id="A0A1C7NEI2"/>
    <dbReference type="OrthoDB" id="70823at2759"/>
    <dbReference type="UniPathway" id="UPA00002">
        <property type="reaction ID" value="UER00468"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004139">
        <property type="term" value="F:deoxyribose-phosphate aldolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016052">
        <property type="term" value="P:carbohydrate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009264">
        <property type="term" value="P:deoxyribonucleotide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046386">
        <property type="term" value="P:deoxyribose phosphate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd00959">
        <property type="entry name" value="DeoC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.70:FF:000044">
        <property type="entry name" value="Deoxyribose-phosphate aldolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00114">
        <property type="entry name" value="DeoC_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011343">
        <property type="entry name" value="DeoC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002915">
        <property type="entry name" value="DeoC/FbaB/LacD_aldolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028581">
        <property type="entry name" value="DeoC_typeI"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00126">
        <property type="entry name" value="deoC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10889">
        <property type="entry name" value="DEOXYRIBOSE-PHOSPHATE ALDOLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10889:SF1">
        <property type="entry name" value="DEOXYRIBOSE-PHOSPHATE ALDOLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01791">
        <property type="entry name" value="DeoC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001357">
        <property type="entry name" value="DeoC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01133">
        <property type="entry name" value="DeoC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51569">
        <property type="entry name" value="Aldolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0456">Lyase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0704">Schiff base</keyword>
    <feature type="active site" description="Schiff-base intermediate with acetaldehyde" evidence="8">
        <location>
            <position position="166"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor/acceptor" evidence="8">
        <location>
            <position position="195"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012515"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00032755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00048791"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR001357-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OBZ87360.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="234" mass="25282" checksum="B2D60A1784164095" modified="2016-11-30" version="1">MTLIVTESLTPEKLAKVFDHAILRPEQTTEDVIQGCEVAKKYNLASVCVKPCDVAQASELLKGTDVMVGTVISFPHGNSTTEAKIAESLQAIEDGAIELDVVLNIGFLRSGLYDKVQSELADIIKLSKAKNPDVSFKIIFETAYLTNEQIVKACELSKNAGAHFVKTSTGFASAGATYEHIELMRGNVPDNMEVKASGGIKTLEQVLKFLELGATRIGSSSSDKIVDEFKKLQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NEJ0</accession>
    <name>A0A1C7NEJ0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_04426</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000216">
        <property type="protein sequence ID" value="OBZ87522.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NEJ0"/>
    <dbReference type="InParanoid" id="A0A1C7NEJ0"/>
    <dbReference type="OrthoDB" id="2301774at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ87522.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="132" mass="14832" checksum="40062025730224AB" modified="2016-11-30" version="1">MEAKKLTADEVSDKCNEWQFLSFSEEEVVYDIVVNVDLLVVSCSCLGFEHRRRLYLLPTSLLAAEEGVSANVTDEAQQKTRSTVKIKAERCVQIEKALHHFNTDLTRMSSYGTDADISIVLKSYENALAAIQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NEK4</accession>
    <name>A0A1C7NEK4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_04414</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000215">
        <property type="protein sequence ID" value="OBZ87542.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NEK4"/>
    <dbReference type="InParanoid" id="A0A1C7NEK4"/>
    <dbReference type="OrthoDB" id="548474at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030674">
        <property type="term" value="F:protein-macromolecule adaptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070682">
        <property type="term" value="P:proteasome regulatory particle assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038966">
        <property type="entry name" value="TMA17"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40422">
        <property type="entry name" value="TRANSLATION MACHINERY-ASSOCIATED PROTEIN 17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40422:SF1">
        <property type="entry name" value="TRANSLATION MACHINERY-ASSOCIATED PROTEIN 17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ87542.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="114" mass="13121" checksum="179874508B26CFEA" modified="2016-11-30" version="1">MESSQLRKALEDLPSHSLITEIPEVQNAIGHLLKSNQEMLEYDPNDPDLQQAIRENKDLIKRKENQVDITLQVIRERLGEAAWREMGSNVKEFREIHADALKEARSNAEEGVFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NEQ9</accession>
    <name>A0A1C7NEQ9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Developmental regulator flbA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">flbA_0</name>
        <name evidence="5" type="ORF">A0J61_04407</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000215">
        <property type="protein sequence ID" value="OBZ87538.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NEQ9"/>
    <dbReference type="FunCoup" id="A0A1C7NEQ9">
        <property type="interactions" value="15"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NEQ9"/>
    <dbReference type="InParanoid" id="A0A1C7NEQ9"/>
    <dbReference type="OrthoDB" id="196547at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035556">
        <property type="term" value="P:intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009968">
        <property type="term" value="P:negative regulation of signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd07440">
        <property type="entry name" value="RGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.167.10">
        <property type="entry name" value="Regulator of G-protein Signalling 4, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000591">
        <property type="entry name" value="DEP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016137">
        <property type="entry name" value="RGS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058855">
        <property type="entry name" value="RGS1/SST2-like_Fungal-DR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036305">
        <property type="entry name" value="RGS_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044926">
        <property type="entry name" value="RGS_subdomain_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10845:SF192">
        <property type="entry name" value="DOUBLE HIT, ISOFORM B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10845">
        <property type="entry name" value="REGULATOR OF G PROTEIN SIGNALING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00610">
        <property type="entry name" value="DEP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00615">
        <property type="entry name" value="RGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25889">
        <property type="entry name" value="WHD_Fungal_DR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00049">
        <property type="entry name" value="DEP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00315">
        <property type="entry name" value="RGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48097">
        <property type="entry name" value="Regulator of G-protein signaling, RGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50186">
        <property type="entry name" value="DEP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50132">
        <property type="entry name" value="RGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0734">Signal transduction inhibitor</keyword>
    <feature type="domain" description="DEP" evidence="4">
        <location>
            <begin position="190"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="domain" description="RGS" evidence="3">
        <location>
            <begin position="397"/>
            <end position="582"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="312"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="358"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="583"/>
            <end position="641"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="324"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="592"/>
            <end position="610"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022700"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50132"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OBZ87538.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="641" mass="72894" checksum="5E2DB1AE79C91783" modified="2016-11-30" version="1">MRMTSQGRPYTKDLYDMFAAVLLQINLTDHRIMFRYYPYTFTTDEAAKVMSNLTFIHVHRDPDPEDPSRQIATRTTTTFSMDSTTARYMLQQFLASRLIMSATDPTNWSMKDKGLWSPTVKGKYVLEEFTDTTQVSMSSNLIAALNAPYMTPGSNGRLITLERLSDNDDQITFSRPNMTMAFKAMMSSLPRDALFMEEIVGIEKRSLSNAYEHTIAGSHCVEWLCDRLTVNSREEAEMVAAQFVMFGWLSLVLDRSDRVLSGKDDVMSFKTNRNAIYYVTERGCLLIGWKPVSMQEDESIISDLSLNEPITPSDTILPRKREISSQSDKLNTASEYHRTAEQANSTAPLQMIRHDSAMQPAETPQPEDQKSRPSSASIAETAPLSDFALIHHSQWTKLMHILETPLIRMYFRDFLSSNYCAENISFWVDHNKLYKTGKSTLEKLADAYTIYELYFSPYAPADLNINHSQNQEIIRYVSTHFAVVQQIPTSTTPHFVVSSSSGQFASPTKSSLKANPRLLLMPPQVASEMSKKRTVVIRGITPEACLVKMLAMYSKVNDHVCRMMAEDSVPKFVKTQKYQDLISRQQKQQQQEESDSDDESIYFEDSDDEDKTMITLATALSAQRSSMEHTRQRDPMATAAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NEW7</accession>
    <name>A0A1C7NEW7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">ATP phosphoribosyltransferase</fullName>
            <ecNumber evidence="5">2.4.2.17</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="primary">HIS1_1</name>
        <name evidence="16" type="ORF">A0J61_04658</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>1-(5-phospho-beta-D-ribosyl)-ATP + diphosphate = 5-phospho-alpha-D-ribose 1-diphosphate + ATP</text>
            <dbReference type="Rhea" id="RHEA:18473"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58017"/>
            <dbReference type="ChEBI" id="CHEBI:73183"/>
            <dbReference type="EC" id="2.4.2.17"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3">Amino-acid biosynthesis; L-histidine biosynthesis; L-histidine from 5-phospho-alpha-D-ribose 1-diphosphate: step 1/9.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the ATP phosphoribosyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.2.17" evidence="5"/>
    <dbReference type="EMBL" id="LUGH01000232">
        <property type="protein sequence ID" value="OBZ87299.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NEW7"/>
    <dbReference type="FunCoup" id="A0A1C7NEW7">
        <property type="interactions" value="126"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NEW7"/>
    <dbReference type="InParanoid" id="A0A1C7NEW7"/>
    <dbReference type="OrthoDB" id="2574at2759"/>
    <dbReference type="UniPathway" id="UPA00031">
        <property type="reaction ID" value="UER00006"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003879">
        <property type="term" value="F:ATP phosphoribosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000105">
        <property type="term" value="P:L-histidine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.120:FF:000003">
        <property type="entry name" value="ATP phosphoribosyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.190.10:FF:000123">
        <property type="entry name" value="HIS1p ATP phosphoribosyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.190.10">
        <property type="entry name" value="Periplasmic binding protein-like II"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00079">
        <property type="entry name" value="HisG_Long"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020621">
        <property type="entry name" value="ATP-PRT_HisG_long"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013820">
        <property type="entry name" value="ATP_PRibTrfase_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018198">
        <property type="entry name" value="ATP_PRibTrfase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001348">
        <property type="entry name" value="ATP_PRibTrfase_HisG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013115">
        <property type="entry name" value="HisG_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011322">
        <property type="entry name" value="N-reg_PII-like_a/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015867">
        <property type="entry name" value="N-reg_PII/ATP_PRibTrfase_C"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00070">
        <property type="entry name" value="hisG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR03455">
        <property type="entry name" value="HisG_C-term"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21403:SF8">
        <property type="entry name" value="ATP PHOSPHORIBOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21403">
        <property type="entry name" value="ATP PHOSPHORIBOSYLTRANSFERASE ATP-PRTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01634">
        <property type="entry name" value="HisG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08029">
        <property type="entry name" value="HisG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54913">
        <property type="entry name" value="GlnB-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53850">
        <property type="entry name" value="Periplasmic binding protein-like II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01316">
        <property type="entry name" value="ATP_P_PHORIBOSYLTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="12" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9 16" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="13" id="KW-0368">Histidine biosynthesis</keyword>
    <keyword evidence="11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10 16" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="ATP phosphoribosyltransferase catalytic" evidence="14">
        <location>
            <begin position="59"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine biosynthesis HisG C-terminal" evidence="15">
        <location>
            <begin position="221"/>
            <end position="293"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000915"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004667"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00009372"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00020998"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF01634"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF08029"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="OBZ87299.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="297" mass="32550" checksum="52B7AFBAE79BCAF0" modified="2016-11-30" version="1">MDFVKDLTDRLLFAVPKKGRLYEQCMQLLNGSDIHFNRRSRQDIALSTNLPIALIFLPAADIPKYVADGNVDLGISGQDMIVENEVQDKVTEIMELGFGKCRLCVQVPIKGPFTNIEELAGKRIVTSFDAFAKKVFEPIDQAKGTKTTINYVSGSVEAACALGLADGIIDLVESGETMRAAGLHDISTLLETQSVLMSNKHSKHQDLIDKITSRIRGVITAEKYVLCTYNVERENLARAVQITPGRQGPTVSSLDSHEGWVAVSAMIEKKKKGEVMDGLSEVGATDILVMSFTNCRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NG42</accession>
    <name>A0A1C7NG42_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Heat shock factor protein 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">HSF2</name>
        <name evidence="9" type="ORF">A0J61_03840</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the HSF family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000174">
        <property type="protein sequence ID" value="OBZ88121.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NG42"/>
    <dbReference type="STRING" id="101091.A0A1C7NG42"/>
    <dbReference type="InParanoid" id="A0A1C7NG42"/>
    <dbReference type="OrthoDB" id="60033at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000232">
        <property type="entry name" value="HSF_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10015:SF427">
        <property type="entry name" value="HEAT SHOCK FACTOR PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10015">
        <property type="entry name" value="HEAT SHOCK TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00447">
        <property type="entry name" value="HSF_DNA-bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00415">
        <property type="entry name" value="HSF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0346">Stress response</keyword>
    <feature type="domain" description="HSF-type DNA-binding" evidence="8">
        <location>
            <begin position="93"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="204"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="271"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="327"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="276"/>
            <end position="291"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006403"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU004020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00415"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OBZ88121.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="499" mass="57388" checksum="A3A5330288184885" modified="2016-11-30" version="1">MNYTYTTDTILGREQDRPFNAVVNQYAMFNERPSVMFDSNAIHSSPILSEETNPLMLIHPMNPIPTNQHFQHPWNPLHDDYSTHHHVAPSERGIAGFVSKLYQCLQSPESNQKYARWCQHEGKDMFVIDCIPEFTEIVLPRLFKHCKFASFVRQLNIYGFQRDTDARKSKDTKEKESCRWYHPCFKPNRRDLFHMIRRKATRYSRKSKAKASMSEEDPETILNVGFGDDESVEMDQDNMVLIVRDDHTRRSSSISSVNTMLPTLNYSTSQLQPGFSTSSEPPISASPTTSPSLVHHLSLESPSFQSDEDILSSFSPQDFRLQFYQMRQKHEQERKEYEGQLQKAFVQIDEQKLHIQQLEEALGFTKHSVKPTTGGYIDTCPTMPSFQLPQHRMVYSKSIIRPDNFYFQDKNDLLLSSPPLVPSNHPSPAGSWHPHVNYVDYHRNSLDEATNGIVTAGSSTVENMVKADELKSATMAYIDSKEKRGSLDVHPTMGFADYM</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NG59</accession>
    <name>A0A1C7NG59_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Septin spn2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">spn2_0</name>
        <name evidence="7" type="ORF">A0J61_03866</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="5">Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000176">
        <property type="protein sequence ID" value="OBZ88082.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NG59"/>
    <dbReference type="FunCoup" id="A0A1C7NG59">
        <property type="interactions" value="94"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NG59"/>
    <dbReference type="InParanoid" id="A0A1C7NG59"/>
    <dbReference type="OrthoDB" id="416553at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032161">
        <property type="term" value="C:cleavage apparatus septin structure"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000921">
        <property type="term" value="P:septin ring assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043934">
        <property type="term" value="P:sporulation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd01850">
        <property type="entry name" value="CDC_Septin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000260">
        <property type="entry name" value="Cell division control 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030379">
        <property type="entry name" value="G_SEPTIN_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016491">
        <property type="entry name" value="Septin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18884">
        <property type="entry name" value="SEPTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00735">
        <property type="entry name" value="Septin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006698">
        <property type="entry name" value="Septin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51719">
        <property type="entry name" value="G_SEPTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="1" id="KW-0132">Cell division</keyword>
    <keyword evidence="3 5" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="2 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Septin-type G" evidence="6">
        <location>
            <begin position="43"/>
            <end position="315"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU004560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51719"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OBZ88082.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="331" mass="37673" checksum="3EB00A0E69271D15" modified="2016-11-30" version="1">MSTSAVSTPTTEQNNQFVPETALNGYVGFDTITQQIERKLLKKGFQFNVMVVGQSGLGKSTLINTIFASHLIDSKGRVEPADLSEQTTEIEAVVHTIIENGVRLRLNIVDTPGYGDQVNNDNCWEPIIKYIKDQHSAYLRKELTAKRERYIVDTRIHCCLFFITPSGHSLKPIDVVVLKKLSEVVNVVPVIAKSDSLTPEERDAFKQRIKAELSFHDIRLYPYESEEDEEQEKALNESIWELIPFAIVGSERNVVVEGKAVRGRKTRWGAINVEDPAHCEFIHLRNFLTRTHLQDLIETTAMIHYETFRAKQLMAIKESTQFQQKPETASE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NG96</accession>
    <name>A0A1C7NG96_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">serine C-palmitoyltransferase</fullName>
            <ecNumber evidence="7">2.3.1.50</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="21" type="primary">Sptlc2_1</name>
        <name evidence="21" type="ORF">A0J61_03818</name>
    </gene>
    <organism evidence="21 22">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="21 22" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="21 22">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="17">
            <text>L-serine + hexadecanoyl-CoA + H(+) = 3-oxosphinganine + CO2 + CoA</text>
            <dbReference type="Rhea" id="RHEA:14761"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:33384"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57379"/>
            <dbReference type="ChEBI" id="CHEBI:58299"/>
            <dbReference type="EC" id="2.3.1.50"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 18">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="4">Lipid metabolism; sphingolipid metabolism.</text>
    </comment>
    <comment type="pathway">
        <text evidence="5">Sphingolipid metabolism.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Endoplasmic reticulum</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="3">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6 18">Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="21">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.50" evidence="7"/>
    <dbReference type="EMBL" id="LUGH01000173">
        <property type="protein sequence ID" value="OBZ88127.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NG96"/>
    <dbReference type="FunCoup" id="A0A1C7NG96">
        <property type="interactions" value="187"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NG96"/>
    <dbReference type="InParanoid" id="A0A1C7NG96"/>
    <dbReference type="OrthoDB" id="65434at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017059">
        <property type="term" value="C:serine palmitoyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004758">
        <property type="term" value="F:serine C-palmitoyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046513">
        <property type="term" value="P:ceramide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046512">
        <property type="term" value="P:sphingosine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06454">
        <property type="entry name" value="KBL_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.640.10:FF:000047">
        <property type="entry name" value="serine palmitoyltransferase 2 isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001917">
        <property type="entry name" value="Aminotrans_II_pyridoxalP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004839">
        <property type="entry name" value="Aminotransferase_I/II_large"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050087">
        <property type="entry name" value="AON_synthase_class-II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13693">
        <property type="entry name" value="CLASS II AMINOTRANSFERASE/8-AMINO-7-OXONONANOATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13693:SF3">
        <property type="entry name" value="LD36009P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00155">
        <property type="entry name" value="Aminotran_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00599">
        <property type="entry name" value="AA_TRANSFER_CLASS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="16" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="10" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="14" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="15 19" id="KW-0472">Membrane</keyword>
    <keyword evidence="11 18" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="22" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="12" id="KW-0746">Sphingolipid metabolism</keyword>
    <keyword evidence="8 21" id="KW-0808">Transferase</keyword>
    <keyword evidence="9 19" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="13 19" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="115"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="domain" description="Aminotransferase class I/classII large" evidence="20">
        <location>
            <begin position="216"/>
            <end position="575"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004760"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00004991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00008392"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00013220"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00048528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="RuleBase" id="RU003693"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="Pfam" id="PF00155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="EMBL" id="OBZ88127.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="591" mass="66135" checksum="F623369206F59226" modified="2016-11-30" version="1">MPTQQLPAIPPIIEEPSEIPSIRIEGVQPSTRKRAFSFTNLVNRTRRAYSVSSTYPAKPPPTLLALPVPKTSHDLLTDFDPSHRKSTLDLTPAQRRNSIAAAQRKYEDFEQKIEAAPLFVLVSTYLNYLVLILFGHLRDILGKVFKRKEYAHLRTNEGYAPLVSDFDSFYTRRMYIRIRDCWNRPTTGVPSRTVTILERESKDFNLTFKLTGKTKEVINFSSYNYLGFAQNEGICADQVEESVREYGITSASTRMEAGNLDIHRDLEKRVAQFVGKEDAIVVSMGFATNSTTIPSLVSKGCLVISDELNHSSIIFGVRLSGASVRVFKHNNMIDLRNLLREVISQGQPRTHRPWKKIVVIVEGLYSMEGSIVNLPELIKLKHEYKFYLYMDEAHSIGALGENGGGICDFYGISPKNVDILMGTFTKSFGAAGGYIAGDKAVIDHLRLKNHAFLYAESMAVPVIQQVSSSMGVIRGEDGTEDGVRRIQDLADNSRYFSNSLRKMGFIVYGDEGSPVIPLLLFNPAKISAFSREMLKRGIAIVVVGYPATPIISSRARFCISSAHTREDLDRTLEHISEVGDLLMLKFKPACT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NGX3</accession>
    <name>A0A1C7NGX3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">A0J61_03953</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000182">
        <property type="protein sequence ID" value="OBZ87999.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NGX3"/>
    <dbReference type="InParanoid" id="A0A1C7NGX3"/>
    <dbReference type="OrthoDB" id="4062651at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050205">
        <property type="entry name" value="CDPK_Ser/Thr_kinases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24349">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="6">
        <location>
            <begin position="73"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OBZ87999.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="439" mass="50967" checksum="85ED773EE4C2BCF1" modified="2016-11-30" version="1" fragment="single">TGKKTSSQPPAVYERYLEPSVAQEESRVDKAQLPEIEKQYYLEASKQLWLKITKYAHQKKVPVINVKQYNVHASSTTPNAEGFFKNVFFDPHDHKKVIQTFKKMTITQRTTEIAGLLTLKGLPHMGQITHVLKEDHGEIIGLCMERYQKTLKQYTHAHSHHRLTAYQKMDLILQMLESIATLHRAGLAHRDLSEVNFMVNQTEYKLRDGSPKAALYLIDFGKSTFTSPDVCRCWWVEQPRLDIQGYDDEIIPRTKEELDVWCRRLPWIPSKPDHGYKLYRSIQTLPKSRSDTEGLAWLVNPVAEDLYSIGTLIWKTFAETEPWYGIMDSDIKALRDIVSDDYRLQKTLEREVRGHLSRELLLKFLKVSPQQRESAESVLAWLSDEAIQNGLIAEWERNAPVARQKRHAKALSAHDEEQAIEFSHFQRKRHKTGYTEADT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NH96</accession>
    <name>A0A1C7NH96_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">UNC93-like protein 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">A0J61_04028</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000188">
        <property type="protein sequence ID" value="OBZ87926.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NH96"/>
    <dbReference type="InParanoid" id="A0A1C7NH96"/>
    <dbReference type="OrthoDB" id="196103at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010291">
        <property type="entry name" value="Ion_channel_UNC-93"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051617">
        <property type="entry name" value="UNC-93-like_regulator"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23294">
        <property type="entry name" value="ET TRANSLATION PRODUCT-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23294:SF59">
        <property type="entry name" value="UNC93-LIKE PROTEIN C922.05C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05978">
        <property type="entry name" value="UNC-93"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="15"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="55"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="98"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="137"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="167"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="225"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="262"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="293"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="336"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="403"/>
            <end position="425"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OBZ87926.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="468" mass="51787" checksum="BB8A907DC18BC88C" modified="2016-11-30" version="1">MGFKLPSFRYNDPNFQVFLVGFICFCCPGMFNALNGMGGAGQADSKTTNDANTALAVTFTVCSLIGAPVFNIFGHRILVPAALAYVLYVGSYLTPNPAFTIATGAILGIGAGFLWTAQAGIMMSYPDEKDKGKAFSIFWMVFNLGATVGAAIPLGNNWTSSVNTVKTSTYIGFMCIMGFGAFLSLALLPPSKVIRANGSPVSLHKFSNWKREAYEVFRMFTDWKMICLIPLFFGSNWFYTYQYQVYNGGGFFTLRARSLNNLLYWLCQIIGAGIFGWLLDWSRLGSRRRRAMIGNAVVFVFLVSAWIGCIFVQQKFTYQSVKEPSFIQADVYSPEFAGYTVLYAVFGFVDAIYQGFIYWLLGTMTNDTERAARYGGFYKTIQNAAAAIAAQVDAIHTPYMTQLYINFVIEGVGLLLAFVVCLQVSDVTVESVDNLMEHSKTTEVMVGGQVELIEGDDFKFVQEKDDAC</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NHA7</accession>
    <name>A0A1C7NHA7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="11">ATP-binding cassette sub-family D member 4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">ABCD4</name>
        <name evidence="11" type="ORF">A0J61_03566</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ABC transporter superfamily. ABCD family. Peroxisomal fatty acyl CoA transporter (TC 3.A.1.203) subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000156">
        <property type="protein sequence ID" value="OBZ88380.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NHA7"/>
    <dbReference type="InParanoid" id="A0A1C7NHA7"/>
    <dbReference type="OrthoDB" id="422637at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005778">
        <property type="term" value="C:peroxisomal membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005324">
        <property type="term" value="F:long-chain fatty acid transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006635">
        <property type="term" value="P:fatty acid beta-oxidation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015910">
        <property type="term" value="P:long-chain fatty acid import into peroxisome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007031">
        <property type="term" value="P:peroxisome organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042760">
        <property type="term" value="P:very long-chain fatty acid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd03223">
        <property type="entry name" value="ABCD_peroxisomal_ALDP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="entry name" value="ABC transporter type 1, transmembrane domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050835">
        <property type="entry name" value="ABC_transporter_sub-D"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11384">
        <property type="entry name" value="ATP-BINDING CASSETTE, SUB-FAMILY D MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11384:SF59">
        <property type="entry name" value="LYSOSOMAL COBALAMIN TRANSPORTER ABCD4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06472">
        <property type="entry name" value="ABC_membrane_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="ABC transporter transmembrane region"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="62"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="104"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="209"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="291"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="327"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="10">
        <location>
            <begin position="165"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="9">
        <location>
            <begin position="396"/>
            <end position="606"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008575"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="OBZ88380.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="606" mass="69792" checksum="39AA9E163ECD5502" modified="2016-11-30" version="1">MTQTEFNGIPLLDPLVDDKPKKHEYKLDRVFFRRLNRLIRILLNSPRKPWSIDRQDRKNSIFWLYTFFLMTNLGQEYLVTFVSVIPSHFYTILTSKDLPGFLKYIVPSMLVVLATSVLRSCLKFLEGLCAIKTRGLLTRWVHHAYIKPKYLYPLVNQKEIDNPDQRISQDIDXFSETLTQILTNLIVAPIMTIYYTYRCWIVTGPLGPLVIFVYFILGTLISRQLIQPIIRPVFFRESQEGHFRFLHVRLRQFAESIAFYGGEEEERKTANESLDTLLEYQRDVIKHTFPLSLANFVFSYVGSIFSYLVIAIPIFSGVYDDKDATELSSIISANAFVSMYLVFLFTSIIQQSTKCSDLAGYVTRIGELLEALDTIAEDNYENSTQHFAQSSDMDWVEFERVELYSPRSQLLLLDFNLKIEPGQHVVFTGSNGSGKTSILRALAGLWPYQGGKIHVPKDIFFLPQLPYLIEGSLKDQLLFPLRSNASLSDHQVQELLEKVHLSHLVQKLASFDKAYSYQTWSELLSPGEQQRLVIARVMYWKPKFVVLDEATSAVDAATESQLYDMLLSQPDMTLISISHHHHVIQSHPIIVHLDGLGQYTINYTHT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NHR4</accession>
    <name>A0A1C7NHR4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_03304</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000139">
        <property type="protein sequence ID" value="OBZ88651.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NHR4"/>
    <dbReference type="InParanoid" id="A0A1C7NHR4"/>
    <dbReference type="OrthoDB" id="2203026at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ88651.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="89" mass="10495" checksum="6D871A08CBD339EA" modified="2016-11-30" version="1">MGLSKTKRQLKEQKEEEDYEWQDIVKTEDGSLRTETRIISNELEEPSWNDEEDCKRVQNVTNAIHNYLGENSKMAISFLLPHSVKQKQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NHW2</accession>
    <name>A0A1C7NHW2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Pyrroline-5-carboxylate reductase</fullName>
            <ecNumber evidence="5">1.5.1.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">proC_0</name>
        <name evidence="8" type="ORF">A0J61_03587</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>L-proline + NADP(+) = (S)-1-pyrroline-5-carboxylate + NADPH + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:14109"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17388"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:60039"/>
            <dbReference type="EC" id="1.5.1.2"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="5">Amino-acid biosynthesis; L-proline biosynthesis; L-proline from L-glutamate 5-semialdehyde: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the pyrroline-5-carboxylate reductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.5.1.2" evidence="5"/>
    <dbReference type="EMBL" id="LUGH01000157">
        <property type="protein sequence ID" value="OBZ88359.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NHW2"/>
    <dbReference type="FunCoup" id="A0A1C7NHW2">
        <property type="interactions" value="166"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NHW2"/>
    <dbReference type="InParanoid" id="A0A1C7NHW2"/>
    <dbReference type="OrthoDB" id="10263291at2759"/>
    <dbReference type="UniPathway" id="UPA00098">
        <property type="reaction ID" value="UER00361"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004735">
        <property type="term" value="F:pyrroline-5-carboxylate reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055129">
        <property type="term" value="P:L-proline biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.3730.10:FF:000001">
        <property type="entry name" value="Pyrroline-5-carboxylate reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3730.10">
        <property type="entry name" value="ProC C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01925">
        <property type="entry name" value="P5C_reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008927">
        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028939">
        <property type="entry name" value="P5C_Rdtase_cat_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053790">
        <property type="entry name" value="P5CR-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029036">
        <property type="entry name" value="P5CR_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000304">
        <property type="entry name" value="Pyrroline-COOH_reductase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00112">
        <property type="entry name" value="proC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11645">
        <property type="entry name" value="PYRROLINE-5-CARBOXYLATE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11645:SF0">
        <property type="entry name" value="PYRROLINE-5-CARBOXYLATE REDUCTASE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03807">
        <property type="entry name" value="F420_oxidored"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14748">
        <property type="entry name" value="P5CR_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000193">
        <property type="entry name" value="Pyrrol-5-carb_rd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48179">
        <property type="entry name" value="6-phosphogluconate dehydrogenase C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00521">
        <property type="entry name" value="P5CR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="2 4 5" id="KW-0521">NADP</keyword>
    <keyword evidence="3 5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-0641">Proline biosynthesis</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pyrroline-5-carboxylate reductase catalytic N-terminal" evidence="6">
        <location>
            <begin position="12"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="domain" description="Pyrroline-5-carboxylate reductase dimerisation" evidence="7">
        <location>
            <begin position="175"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="15"/>
            <end position="20"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="64"/>
        </location>
        <ligand>
            <name>NADPH</name>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="77"/>
            <end position="80"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR000193-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003903"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF03807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF14748"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OBZ88359.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="287" mass="31085" checksum="60588C02C12146E1" modified="2016-11-30" version="1">MVSLNKQLKPVISFIGGGNMAEAILCGLQSSGHPSSRLRYSEPLDERRHYMQERYPKMVGSDNNKDAVQGADVVVLAVKPQVLRSVVAELGQTISNRPDTLIVSIAAGITTKDIYKWLKVSHPVSIVRCMPNTPALIGEGAVGLFATDHVNDKQKELTQDIMKAIAKQVSWVQEEALIDTVTGISGSGPAYFFLIMEAMQNAGVEAGLTPEEAKALTLQTCFGAARMAQTSSDDLATLRRKVTSPKGTTEAAIHSMETNEIRKVMAEAVFSAQNRGRELAEELGKEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NI60</accession>
    <name>A0A1C7NI60_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_04934</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000253">
        <property type="protein sequence ID" value="OBZ87014.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NI60"/>
    <dbReference type="STRING" id="101091.A0A1C7NI60"/>
    <dbReference type="InParanoid" id="A0A1C7NI60"/>
    <dbReference type="OrthoDB" id="165058at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ87014.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="206" mass="23035" checksum="C2FAF5D5C779CEA0" modified="2016-11-30" version="1">MRPPITTTNKISNFLLDPWGTAKVVLPSAALQVVLHQTVMKKASLRELTLGLTLLNAIWFATSLNLNFLETPLLANVPSLDDWNKLDVGRHRFSLINKIEGAVSLLSLNVFLHWNERIVRHDGYVDNLLKAASLAPIAITVIHSVYLLPKFNRRAEEVAQGGPTAQELWEKDPFFLKGHRSYIAFDTIKISALAVAGLRYGLMLKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NIA4</accession>
    <name>A0A1C7NIA4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_03119</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000129">
        <property type="protein sequence ID" value="OBZ88821.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NIA4"/>
    <dbReference type="InParanoid" id="A0A1C7NIA4"/>
    <dbReference type="OrthoDB" id="2219730at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ88821.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="126" mass="14376" checksum="61F84FCFEB7BADCE" modified="2016-11-30" version="1">MWKHRESHLVDIYKTNPESEKKATMQTSDAKPIYPGCEFDVFQSTTQSKEDQFAPLYSVEKVTPKPIEPYQAEDVYAQANQTTNKHATPSIAHVFIQPTASIHTPIANMFLEKQKDDSNQVDLEYA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NIJ4</accession>
    <name>A0A1C7NIJ4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">WD repeat-containing protein JIP5</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">WD repeat-containing protein jip5</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">Wdr55</name>
        <name evidence="8" type="ORF">A0J61_03018</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the WD repeat WDR55 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000123">
        <property type="protein sequence ID" value="OBZ88932.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NIJ4"/>
    <dbReference type="FunCoup" id="A0A1C7NIJ4">
        <property type="interactions" value="541"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NIJ4"/>
    <dbReference type="InParanoid" id="A0A1C7NIJ4"/>
    <dbReference type="OrthoDB" id="2288928at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050505">
        <property type="entry name" value="WDR55/POC1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44019">
        <property type="entry name" value="WD REPEAT-CONTAINING PROTEIN 55"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44019:SF20">
        <property type="entry name" value="WD REPEAT-CONTAINING PROTEIN 55"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24796">
        <property type="entry name" value="WDR55"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 6" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="97"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="138"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="266"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="306"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="306"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="325"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="341"/>
            <end position="360"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007625"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00039238"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00039514"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OBZ88932.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="369" mass="41626" checksum="B403B1491AB5E150" modified="2016-11-30" version="1">MNTSEKKPTSIALDSNVFHLDVHPSQNLVVTGMINGRMQCYRYGLEGNEQVWNSKTFKKSCRGVAFSQDGSSIYGISRDKSIRVLDTETANVLTLKEEAHESPINALLMMDDHLMATGDDQGVIKIWDNRKQDPVMTYTEHEDYIADMVYSAPQRTLIAVGGDGYLSTWDIRKTNVAAMSDQMEDELLSIALVKNGKKAVVGTQDGVLSLWTWGDWGDYNDRIIGHPNSIDAICKLDEDTVCTGSSDGIIRLVTILPNEFHGALGDHGEDMPIENLKLSHDKQYLISSGHDDQLQFWNVAHLFQEDEEKEEDEEKEEVPQPKEVDSDDGWGTDSDDEKEKKKNKRKKTQKKSKPEKKKQMKSTAFFADM</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-06-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NIY3</accession>
    <name>A0A1C7NIY3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_03200</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000133">
        <property type="protein sequence ID" value="OBZ88769.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NIY3"/>
    <dbReference type="InParanoid" id="A0A1C7NIY3"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ88769.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="20" mass="2468" checksum="708907BBF7384749" modified="2016-11-30" version="1">MRLQQMSLSMIHRLVLLLRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NJL6</accession>
    <name>A0A1C7NJL6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_02633</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000101">
        <property type="protein sequence ID" value="OBZ89317.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NJL6"/>
    <dbReference type="InParanoid" id="A0A1C7NJL6"/>
    <dbReference type="OrthoDB" id="2268597at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="27"/>
            <end position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ89317.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="86" mass="9659" checksum="ED419C576EFFB0A4" modified="2016-11-30" version="1">MNPGAVSYPPDNLNEMAPPQKVTGSAETERQQELEAAPKKTDSKNHSIRDSLHEVKENIKETFQSDHHHGQEGQKRPQDGKTNPME</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NJN1</accession>
    <name>A0A1C7NJN1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Protein phosphatase</fullName>
            <ecNumber evidence="1">3.1.3.16</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">PPTC7</name>
        <name evidence="4" type="ORF">A0J61_02751</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>O-phospho-L-seryl-[protein] + H2O = L-seryl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:20629"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="EC" id="3.1.3.16"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:47004"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="EC" id="3.1.3.16"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the PP2C family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.16" evidence="1"/>
    <dbReference type="EMBL" id="LUGH01000108">
        <property type="protein sequence ID" value="OBZ89198.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NJN1"/>
    <dbReference type="FunCoup" id="A0A1C7NJN1">
        <property type="interactions" value="283"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NJN1"/>
    <dbReference type="InParanoid" id="A0A1C7NJN1"/>
    <dbReference type="OrthoDB" id="60843at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004722">
        <property type="term" value="F:protein serine/threonine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.40.10">
        <property type="entry name" value="PPM-type phosphatase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036457">
        <property type="entry name" value="PPM-type-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001932">
        <property type="entry name" value="PPM-type_phosphatase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039123">
        <property type="entry name" value="PPTC7"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12320">
        <property type="entry name" value="PROTEIN PHOSPHATASE 2C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12320:SF1">
        <property type="entry name" value="PROTEIN PHOSPHATASE PTC7 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07228">
        <property type="entry name" value="SpoIIE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00331">
        <property type="entry name" value="PP2C_SIG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00332">
        <property type="entry name" value="PP2Cc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81606">
        <property type="entry name" value="PP2C-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51746">
        <property type="entry name" value="PPM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0460">Magnesium</keyword>
    <keyword evidence="1" id="KW-0464">Manganese</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1" id="KW-0904">Protein phosphatase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PPM-type phosphatase" evidence="3">
        <location>
            <begin position="110"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="52"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="64"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU366020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51746"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OBZ89198.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="379" mass="41881" checksum="BB5CCC203C67898A" modified="2016-11-30" version="1">MRPYIQRIAAASLLLRSSRLAWTNTTYLKPALAHQLPYYFQQQLLEAPSHSRHFSNSHASSHLNTATVAPEEENTTNNNAASEKFQFIAYAAWHPKSRQKPASPTQKKVPYWKEHSKAGKVDAGEDAFFQTNTPEGLAIGVADGVGGWSSVGVDPALFSWALMDNAALVAKTEKSIDAHQILDIAFHELTASKKVSAGSSTACILNLSKKTGEMTTCNLGDSAFLLVRKKKIVYESPSQQHYFNCPYQLTVVPDTYPNRDQLVTDLPKDADTKSFFLKEGDLILLATDGYFDNMYAEETLELINEGMKPISESSNADDELITATIRTLAKTLTDRARRLSLNPKRLSPWAKAAQAHGSNYRGGKVDDITCIVTLVCHKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-06-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NJR3</accession>
    <name>A0A1C7NJR3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_04420</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000216">
        <property type="protein sequence ID" value="OBZ87524.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NJR3"/>
    <dbReference type="InParanoid" id="A0A1C7NJR3"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ87524.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="103" mass="11863" checksum="1CF6F2885859362A" modified="2016-11-30" version="1">MMIGRLYHDIIRVDGLKADKPWREEGERSASLLKHLSSSLTMQRTISSLRDPSENHIIIGTAYKTSAMDDFSDQLYISELVDLASLHCRPWPNHLGDYKEYLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NJU5</accession>
    <name>A0A1C7NJU5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">DNA excision repair protein ERCC-1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">ERCC1</name>
        <name evidence="10" type="ORF">A0J61_02543</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ERCC1/RAD10/SWI10 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000097">
        <property type="protein sequence ID" value="OBZ89413.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NJU5"/>
    <dbReference type="FunCoup" id="A0A1C7NJU5">
        <property type="interactions" value="76"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NJU5"/>
    <dbReference type="InParanoid" id="A0A1C7NJU5"/>
    <dbReference type="OrthoDB" id="10262814at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070522">
        <property type="term" value="C:ERCC4-ERCC1 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000110">
        <property type="term" value="C:nucleotide-excision repair factor 1 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003684">
        <property type="term" value="F:damaged DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006302">
        <property type="term" value="P:double-strand break repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006312">
        <property type="term" value="P:mitotic recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006289">
        <property type="term" value="P:nucleotide-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070914">
        <property type="term" value="P:UV-damage excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd22325">
        <property type="entry name" value="ERCC1_C-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.150.20:FF:000017">
        <property type="entry name" value="DNA excision repair protein ERCC-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.10130:FF:000001">
        <property type="entry name" value="DNA excision repair protein ERCC-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.20">
        <property type="entry name" value="5' to 3' exonuclease, C-terminal subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047260">
        <property type="entry name" value="ERCC1-like_central_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004579">
        <property type="entry name" value="ERCC1/RAD10/SWI10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011335">
        <property type="entry name" value="Restrct_endonuc-II-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010994">
        <property type="entry name" value="RuvA_2-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00597">
        <property type="entry name" value="rad10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12749:SF0">
        <property type="entry name" value="DNA EXCISION REPAIR PROTEIN ERCC-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12749">
        <property type="entry name" value="EXCISION REPAIR CROSS-COMPLEMENTING 1 ERCC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14520">
        <property type="entry name" value="HHH_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03834">
        <property type="entry name" value="Rad10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52980">
        <property type="entry name" value="Restriction endonuclease-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47781">
        <property type="entry name" value="RuvA domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0227">DNA damage</keyword>
    <keyword evidence="5" id="KW-0234">DNA repair</keyword>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ERCC1-like central" evidence="9">
        <location>
            <begin position="85"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="14"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="38"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008283"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00071993"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF03834"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OBZ89413.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="284" mass="32501" checksum="C1165455D04DEF82" modified="2016-11-30" version="1">MNPSKETNLPSFEEIERQRQEKSKQNISFFQAKRALDSNTANSNTNISTTINSTPEQLPGFSRPPPPTTTPQRPYLSKPTGPNAILVNPTQQKNPILKHVHNVPWEPSSAIKMDYVVGQTTGVIYLSLRYHRLYPTYIYDRLNAVKNLYVCRILLVYVDIDSYHDALREINRIAILSEFTLILAWSPEEAGRYLETFKALENRSPDLIREKVEDEFMAKITDCLTQVRSVNKTDVLTLLSTFGSLKKISEASPDQLAMCPGFGEQKVRRLQQVWKQPFIVNNKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NJX7</accession>
    <name>A0A1C7NJX7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">ENTH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_02666</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000103">
        <property type="protein sequence ID" value="OBZ89290.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NJX7"/>
    <dbReference type="FunCoup" id="A0A1C7NJX7">
        <property type="interactions" value="315"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NJX7"/>
    <dbReference type="InParanoid" id="A0A1C7NJX7"/>
    <dbReference type="OrthoDB" id="4033880at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030125">
        <property type="term" value="C:clathrin vesicle coat"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005768">
        <property type="term" value="C:endosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030276">
        <property type="term" value="F:clathrin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005543">
        <property type="term" value="F:phospholipid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006897">
        <property type="term" value="P:endocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006895">
        <property type="term" value="P:Golgi to endosome transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd16992">
        <property type="entry name" value="ENTH_Ent3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.90:FF:000006">
        <property type="entry name" value="Clathrin interactor 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013809">
        <property type="entry name" value="ENTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008942">
        <property type="entry name" value="ENTH_VHS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12276:SF45">
        <property type="entry name" value="CLATHRIN INTERACTOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12276">
        <property type="entry name" value="EPSIN/ENT-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01417">
        <property type="entry name" value="ENTH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00273">
        <property type="entry name" value="ENTH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48464">
        <property type="entry name" value="ENTH/VHS domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50942">
        <property type="entry name" value="ENTH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ENTH" evidence="2">
        <location>
            <begin position="20"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="235"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="299"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="351"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="420"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="254"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="276"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="300"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="326"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="420"/>
            <end position="435"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ89290.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="445" mass="49236" checksum="C7615B5E3EB92621" modified="2016-11-30" version="1">MNFQVPDIWEVKDVVNKLKNVVLNYTEMESKVHEATNNEPWGASSTLLQEIAQGTYNYQYFNEIMPTIYRRFTEKESRQWRQIYKALVLLEYLIKNGSERVIDDARAHISMVKVMRNFFYIDDKGKDEGINVRNRAKEIVELLGDTEKIRSERKLAKKNRTKYIGVGSDSLGGRESMRGGMGVSGISKYVGFGNDTFGSGGNRGISFNGDALTFEGEVNPYPRQTSVGKYDIDDDEEEVDDFGPKVSASQTKSHHADNNKSNDDDWGDFEFGGVAQSSTTSSNQQQNVLDDDFSDFQVASTSQTTTSQSSKQPDLFDLLNDDNHGTTHTATPGSTHSLSAFETKQPMTPRTLAATVSPPPPAPPQASSNPEPVPATTGIWAQASGFVALDSLGKKTNLNTPTIGPSMNTLKNTNIQADWNNWATNNPQQPQTPKKSTAFDDLLSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NKE9</accession>
    <name>A0A1C7NKE9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_04184</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000199">
        <property type="protein sequence ID" value="OBZ87764.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NKE9"/>
    <dbReference type="InParanoid" id="A0A1C7NKE9"/>
    <dbReference type="OrthoDB" id="2241190at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ87764.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="84" mass="9626" checksum="4C342EF948A2D21A" modified="2016-11-30" version="1">MEEIIGTLFTNGLLAFYLNTLFTAKMNVRFICENGKVSMRSPIEKNEDEVRAYRKHGDDVKEQLFFLVYEKAMTSGQTATVLVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NKX8</accession>
    <name>A0A1C7NKX8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_02164</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000078">
        <property type="protein sequence ID" value="OBZ89781.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NKX8"/>
    <dbReference type="InParanoid" id="A0A1C7NKX8"/>
    <dbReference type="OrthoDB" id="2290155at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ89781.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="305" mass="35382" checksum="142F7C16A4CBC5C4" modified="2016-11-30" version="1">MDQPILSSNIKYNTIEALFKSLDDDILILEQPVNTLVSKITEGPLDIWLDEQSSSNFQLADTDTGEKADYIPSEAPSSTELDDIIYISDDEPSSIIFIDSDSEDEVCYLCHVECTSSKAYREKERNLKSKCWLRGKVYCLGCARLLEFPSTDMERREMLSYLITGKIPRHDQPPNLSSNQVLRRLQHRYEIMKARWQFKTSSKSRSFPLAFNDLLQIYHQERQTCQMSGLRCYIHDARYKRVPYWALTLDHITPVSHRWHDRNLWAVGNLQTMSSVLNSVKSDATDNELAGWYKRFLDAHLVVID</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NL35</accession>
    <name>A0A1C7NL35_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Arf-GAP domain and FG repeat-containing protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">Agfg1</name>
        <name evidence="7" type="ORF">A0J61_02160</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000078">
        <property type="protein sequence ID" value="OBZ89785.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NL35"/>
    <dbReference type="STRING" id="101091.A0A1C7NL35"/>
    <dbReference type="InParanoid" id="A0A1C7NL35"/>
    <dbReference type="OrthoDB" id="6036at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd08838">
        <property type="entry name" value="ArfGap_AGFG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.220.150">
        <property type="entry name" value="Arf GTPase activating protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052248">
        <property type="entry name" value="Arf-GAP_FG-repeat_protein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037278">
        <property type="entry name" value="ARFGAP/RecO"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001164">
        <property type="entry name" value="ArfGAP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038508">
        <property type="entry name" value="ArfGAP_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46134:SF3">
        <property type="entry name" value="ARFGAP WITH FG REPEATS 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46134">
        <property type="entry name" value="DRONGO, ISOFORM F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01412">
        <property type="entry name" value="ArfGap"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00405">
        <property type="entry name" value="REVINTRACTNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00105">
        <property type="entry name" value="ArfGap"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57863">
        <property type="entry name" value="ArfGap/RecO-like zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50115">
        <property type="entry name" value="ARFGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Arf-GAP" evidence="6">
        <location>
            <begin position="15"/>
            <end position="129"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50115"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OBZ89785.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="319" mass="35714" checksum="5A85E61C0079ECE4" modified="2016-11-30" version="1">MAAILAKKQEEWNAQKLQELLRRPENKKCFDCPTKSPFFVNVSIQTFVCVRCSGLVREVGHRVKSISASKFSGPEVVALEYGGNEVARAIWLNGYNHNLPEPETDGDVRLFMRQKYYEQKWLDRKRGMAHAEHVKRIITDMFKEDGTRKKPLSKPTLDIQSKPSMIHSDSWVDDNVPIGLISTVKNNNNRMNDVLLNKDMMLSPKSPTFPQTNKTNDIFSELASLDSTVTTTTPSTIVNTSPTSIGYMGHILQPNTPVNASPVNASPINASPMRISPVHTISSLDPYEALRDLSPTVTSPSTGKMTQSLFHDLDPLFKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NLQ1</accession>
    <name>A0A1C7NLQ1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Protein IMPACT</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">Impact</name>
        <name evidence="8" type="ORF">A0J61_02166</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the IMPACT family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000078">
        <property type="protein sequence ID" value="OBZ89779.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NLQ1"/>
    <dbReference type="FunCoup" id="A0A1C7NLQ1">
        <property type="interactions" value="441"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NLQ1"/>
    <dbReference type="InParanoid" id="A0A1C7NLQ1"/>
    <dbReference type="OrthoDB" id="69641at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140469">
        <property type="term" value="P:GCN2-mediated signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006446">
        <property type="term" value="P:regulation of translational initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd23821">
        <property type="entry name" value="RWD_IMPACT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.30">
        <property type="entry name" value="Impact, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.110.10">
        <property type="entry name" value="Ubiquitin Conjugating Enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023582">
        <property type="entry name" value="Impact"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001498">
        <property type="entry name" value="Impact_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036956">
        <property type="entry name" value="Impact_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_Su5_D2-typ_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006575">
        <property type="entry name" value="RWD_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016135">
        <property type="entry name" value="UBQ-conjugating_enzyme/RWD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16301">
        <property type="entry name" value="IMPACT-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16301:SF25">
        <property type="entry name" value="PROTEIN IMPACT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01205">
        <property type="entry name" value="Impact_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05773">
        <property type="entry name" value="RWD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00591">
        <property type="entry name" value="RWD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="Ribosomal protein S5 domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54495">
        <property type="entry name" value="UBC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50908">
        <property type="entry name" value="RWD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0678">Repressor</keyword>
    <keyword evidence="6" id="KW-0346">Stress response</keyword>
    <keyword evidence="5" id="KW-0810">Translation regulation</keyword>
    <feature type="domain" description="RWD" evidence="7">
        <location>
            <begin position="15"/>
            <end position="124"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007665"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022845"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50908"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OBZ89779.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="321" mass="36713" checksum="4B2DD323B88C2929" modified="2016-11-30" version="1">MDKESEAENREYQNEELMAIEAIYPDAFKKDTSSPDAYNYTLNLDEDDPDLRSPRKLVVRFFLPPTYPGQDMPIYEIASVYCGTKKVDDPMLDAIDAGFQSLYQPGQVVLFEWISWLRDYLEDHVERPTSQEHQLVESTATLSIQEEEEIQEEKEHVDLNKNLEEEVDRPTVRSLMGNNSYHTEKPPMIFSSEPLVDRKSTFVAHVAEVHSVHEVKVVLAHLLQNKKIAKATHNILAYRIMMPDGKVLQDNDDDGESAAGGRLSHLMQILEVENVVVVVTRWFGGIHLGPDRFKDINNVARNALEECGFIKNKNTKGKKKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NM21</accession>
    <name>A0A1C7NM21_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">A0J61_01742</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the glycosyl hydrolase 5 (cellulase A) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000059">
        <property type="protein sequence ID" value="OBZ90193.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NM21"/>
    <dbReference type="STRING" id="101091.A0A1C7NM21"/>
    <dbReference type="InParanoid" id="A0A1C7NM21"/>
    <dbReference type="OrthoDB" id="9971853at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050295">
        <property type="term" value="F:steryl-beta-glucosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1904462">
        <property type="term" value="P:ergosteryl 3-beta-D-glucoside catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000272">
        <property type="term" value="P:polysaccharide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1180">
        <property type="entry name" value="Golgi alpha-mannosidase II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041036">
        <property type="entry name" value="GH5_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001547">
        <property type="entry name" value="Glyco_hydro_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013780">
        <property type="entry name" value="Glyco_hydro_b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052066">
        <property type="entry name" value="Glycosphingolipid_Hydrolases"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31308">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31308:SF5">
        <property type="entry name" value="ERGOSTERYL-BETA-GLUCOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00150">
        <property type="entry name" value="Cellulase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18564">
        <property type="entry name" value="Glyco_hydro_5_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glycoside hydrolase family 5" evidence="4">
        <location>
            <begin position="75"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="domain" description="Glycoside hydrolase family 5 C-terminal" evidence="5">
        <location>
            <begin position="551"/>
            <end position="650"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF18564"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OBZ90193.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="666" mass="76150" checksum="254C8333980CA569" modified="2016-11-30" version="1">MSSQGAQDLSFAIRHEGASFKDPYGRSLLMRGINVCGSSKLPTKPYLGSTHLYDEKLFWDHRNVSFVGRPFPLEEADEHFSRLRAWGLTLIRLLVPWESLEHAGPGQYDEEYIDYLRALISKMPEYGLQCVIDPHQDTWSRFSGGSGAPGWTFEVAGMNMKHFKETGAAYVHNTNAVPGDPLPMVWPTNYTKLASCTMFTLFFGGDIFAPKRTYEGKPVQQFMNDCFINCYQHLATRLVDLKAVLAFEFMNEPHPGYIGLPHLDSFDPITNLIFGDSPTPLQSFALGDRIPQRVGVHIKSWPFPTKKSHERIINPNRLSAWTGECVWREHGVWKPDEVTGDPVLVDTAYFSKHPLTGQKVSFYDDFYKPLVNRYVKAIQAVKSDWYCLVEPLANERAPIYTEKDHHDHVVFSPHWYDLNCVFYKKFDGRMTHDVQSLQRGGNVFSATYFGRNGAKKNYAKQIKNIKEDGLQDMGQKPCILGEVVAHPICFRLWNYDVCNDHIYGDHWNGENFSIYSAKKQNEDYKEHNDGNSKLSKKHLYDGGRVLEAVLRPYACKIAGTPVHSEFDLDSLCYTFSFLPFTAQERQAQKEKGYKALDKMAYTTELFVPFFHFGGKELKIEATSGECVYDEDRQTLYHTYDDQINSNITITLSVLNHTVPQGHCSIM</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NM25</accession>
    <name>A0A1C7NM25_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">O-methylsterigmatocystin oxidoreductase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">A0J61_01817</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000062">
        <property type="protein sequence ID" value="OBZ90125.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NM25"/>
    <dbReference type="STRING" id="101091.A0A1C7NM25"/>
    <dbReference type="InParanoid" id="A0A1C7NM25"/>
    <dbReference type="OrthoDB" id="3934656at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050364">
        <property type="entry name" value="Cytochrome_P450_fung"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46300:SF11">
        <property type="entry name" value="OXIDOREDUCTASE, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46300">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0349">Heme</keyword>
    <keyword evidence="3 4 5" id="KW-0408">Iron</keyword>
    <keyword evidence="1 4 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="2 5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" description="axial binding residue" evidence="4">
        <location>
            <position position="460"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OBZ90125.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="521" mass="58851" checksum="1EFE705BA85E5173" modified="2016-11-30" version="1">MERAVEYLKNVKLPSRLEHNHTIPAIGIGAALLYTSYRLFSQDRKTITDRSLKEIPVPGSCYPYVGHMFSLGKLPGEQVTEWHKQLGPIIKIKMGQKTWIMVSDPVLAHKIFVGSGAETSYRPYGVFNYEYYSKGGKGIVFAQPGPSFKKNRAAVLSVLAPSQMEKFMNNVEEESVDFAKRLISATEQNESIDPIKFLELNSMNVIFQALFGRKFDSIQDPEFCKLSEMVERSAGYAGLDQDLPNFLPILSLFKSVFNKTKQWARYVNEERDPAFKKLIEEAYEQEGPNVVKMLDEFDMDLEEKIIFMSDLHAAGTDTVSTTLSWTFVLMCGYPTVQKRAIDEIDAFIKTHGHVPSFADRLEVPLCISIMKECMRFKPPSPFGLPHSVAEDFVVDGYLIPKDATILSSMNAMHYDPERFSNPEVFNPERFMDNLKTMQAAANGSIENRDHFIFGWGRRVCPGIYLAEAEIFSAFVQLLARASIEPGDEGLPDLNSTINGGLVLQPLPHKLKFVQRHDALVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NM30</accession>
    <name>A0A1C7NM30_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_01865</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000064">
        <property type="protein sequence ID" value="OBZ90088.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NM30"/>
    <dbReference type="InParanoid" id="A0A1C7NM30"/>
    <dbReference type="OrthoDB" id="2287448at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="55"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="182"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="84"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="108"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="154"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="213"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="229"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="245"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="287"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="337"/>
            <end position="348"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ90088.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="348" mass="38861" checksum="20B5F74D91E7DB3C" modified="2016-11-30" version="1">MEAFLTTLPPYVHAFLNKHPPTDVFNLLRELICFAVLYSEDRERINQVTHELLEKRNEQSADEEEREEKEAVVPNSGTMQPIQEEQHEPEPISEPEKPKLPNTFPEWWGHREYEPPKQLEKKPVELSTKSASPEPSIHHINRASPSPPPQSYPTTWVSFDAPSTTHDDPHFFRLERARSQIIPHLREYPEQKSPPVRAGTVSGTSSKRHSMINPKTSTSSSAQPVSPRPAKASPSVVAKKALHRASTTVCESPVSTSASDKPKSSPPVTRSASLALKTPRPNAAMRARAEHAKQQQEELERKKNAPVAGAAIGAKLKQRVNSGIDWDTIKKGRRQTIAEQPNSAAQKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NMC0</accession>
    <name>A0A1C7NMC0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Apoptotic chromatin condensation inducer in the nucleus</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">A0J61_02358</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000087">
        <property type="protein sequence ID" value="OBZ89596.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NMC0"/>
    <dbReference type="STRING" id="101091.A0A1C7NMC0"/>
    <dbReference type="InParanoid" id="A0A1C7NMC0"/>
    <dbReference type="OrthoDB" id="5348404at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd12432">
        <property type="entry name" value="RRM_ACINU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.720.30">
        <property type="entry name" value="SAP domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034257">
        <property type="entry name" value="Acinus_RRM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032552">
        <property type="entry name" value="RSB_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003034">
        <property type="entry name" value="SAP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036361">
        <property type="entry name" value="SAP_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47031">
        <property type="entry name" value="SAP DNA-BINDING DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47031:SF3">
        <property type="entry name" value="SAP DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16294">
        <property type="entry name" value="RSB_motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02037">
        <property type="entry name" value="SAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00513">
        <property type="entry name" value="SAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF68906">
        <property type="entry name" value="SAP domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50800">
        <property type="entry name" value="SAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="SAP" evidence="5">
        <location>
            <begin position="6"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="4">
        <location>
            <begin position="297"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="62"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="137"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="238"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="26"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="62"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="82"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="141"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="172"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="248"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="274"/>
            <end position="289"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50800"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OBZ89596.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="494" mass="55848" checksum="425F8B30F277538B" modified="2016-11-30" version="1">MSSKAPSSLKVVELREELSKRNLSTKGKKEELINRLTEALEAEKDQTQEETTQEAVNHEAVVEQQSVTDQVEEVVSVTTTEADTKTAEDLKEELTTKAETEIAKVAEEQTTEQVIEQTTEQVIEQTTEQVIEQVTEQVTEQPKEEPKSEPKDEVMNEPVEEPVVKNVAELTDQPKEEQKEEPIVEAMVESTTETTVEAMVESTAEQPKEGSKVELKEQIVEEQTKESTVVVTESVIEEPMEEDKLEAKNTSQQQATISPNEVSTADDSNKRKRALETTDEHEEKRTKVDDTDGISAAALYVKGFIRPLIIRHVQELFSKHGTVKRFWMDMIKTHCYVIYENESEAKEAFNHINGIVFPPETGRELTAGYLTQDQAEQLIEHEQSAADKRMKVDWESCISKIKAGESLASSPTPEATRKLRTTGINQIARQLAQAAEPAVQPTREVHIATRQERPSRDLSLDELFKKTATLPHLYYLPNTDEEAKKIMEKLQHIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NMD1</accession>
    <name>A0A1C7NMD1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Putative eukaryotic translation initiation factor 5</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">A0J61_01631</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the eIF-2-beta/eIF-5 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000054">
        <property type="protein sequence ID" value="OBZ90313.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NMD1"/>
    <dbReference type="FunCoup" id="A0A1C7NMD1">
        <property type="interactions" value="925"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NMD1"/>
    <dbReference type="InParanoid" id="A0A1C7NMD1"/>
    <dbReference type="OrthoDB" id="10250831at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033290">
        <property type="term" value="C:eukaryotic 48S preinitiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043614">
        <property type="term" value="C:multi-eIF complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071074">
        <property type="term" value="F:eukaryotic initiation factor eIF2 binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005092">
        <property type="term" value="F:GDP-dissociation inhibitor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042256">
        <property type="term" value="P:cytosolic ribosome assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001732">
        <property type="term" value="P:formation of cytoplasmic translation initiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045947">
        <property type="term" value="P:negative regulation of translational initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd11561">
        <property type="entry name" value="W2_eIF5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.180:FF:000031">
        <property type="entry name" value="Eukaryotic translation initiation factor 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.20.25.350:FF:000001">
        <property type="entry name" value="Eukaryotic translation initiation factor 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.30.170:FF:000002">
        <property type="entry name" value="Eukaryotic translation initiation factor 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.25.350">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.30.170">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045196">
        <property type="entry name" value="IF2/IF5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002735">
        <property type="entry name" value="Transl_init_fac_IF2/IF5_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016189">
        <property type="entry name" value="Transl_init_fac_IF2/IF5_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016190">
        <property type="entry name" value="Transl_init_fac_IF2/IF5_Zn-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003307">
        <property type="entry name" value="W2_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23001">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23001:SF7">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01873">
        <property type="entry name" value="eIF-5_eIF-2B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02020">
        <property type="entry name" value="W2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00653">
        <property type="entry name" value="eIF2B_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00515">
        <property type="entry name" value="eIF5C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100966">
        <property type="entry name" value="Translation initiation factor 2 beta, aIF2beta, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75689">
        <property type="entry name" value="Zinc-binding domain of translation initiation factor 2 beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51363">
        <property type="entry name" value="W2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="2 8" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="W2" evidence="7">
        <location>
            <begin position="240"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="149"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="163"/>
            <end position="178"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010397"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OBZ90313.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="401" mass="44499" checksum="047E3C7214C2F062" modified="2016-11-30" version="1">MAAINVRRDVQDSFYRYKMPRLTAKVEGKGNGIKTVITNMAEIARALSRPPSYPTKFFGCELGAQVKCDDKNERYIVNGDHDAAKLQNTLDGFINKFVLCQSCKNPETDIIIKNDEILMDCKACGARNGADMRHKLSAFIVKNPPAVASKNVRKQRKAATAQANNTGEDADNANNGAENDGDGSDDDIISQRIQKQAAGLNMESKLALEDWSEDTSEAAVAQRMKELSVKGAGAFVDDDDEGGENKYESFGVWLLENKGGYTDAEVLEKAEELGVLGKYKACQVLIQGLFDENIISQIPKRAKLLQKFVTDEKSQKATLGGIERLVGMDYKEALLKKVPTILMKIYDLDIIEDDVFIKWGEKPSKRYVERDVSKEIKKAAAPFLEWVENASEEESSDEESD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NMM1</accession>
    <name>A0A1C7NMM1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">TMEM14 protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">A0J61_01677</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TMEM14 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000056">
        <property type="protein sequence ID" value="OBZ90268.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NMM1"/>
    <dbReference type="FunCoup" id="A0A1C7NMM1">
        <property type="interactions" value="31"/>
    </dbReference>
    <dbReference type="InParanoid" id="A0A1C7NMM1"/>
    <dbReference type="OrthoDB" id="5620at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.1740">
        <property type="entry name" value="Transmembrane protein 14-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005349">
        <property type="entry name" value="TMEM14"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044890">
        <property type="entry name" value="TMEM14_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12668:SF53">
        <property type="entry name" value="TMEM14 PROTEIN HOMOLOG YJR085C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12668">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 14, 15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03647">
        <property type="entry name" value="Tmemb_14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007590"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OBZ90268.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="103" mass="10600" checksum="FFF1EA05B802EDDC" modified="2016-11-30" version="1">MSHHPSYTMAGLCAAGGIAGFARTRSVPSLVAGLGVGALYGTAGYLMQENKDYGHETAVAASVILGGAMIPRAVKTRKPVPIALSLISLAAGSYYVKKVIEYS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NNY7</accession>
    <name>A0A1C7NNY7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Glycine cleavage system P protein</fullName>
            <ecNumber evidence="7">1.4.4.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">gcvP</name>
        <name evidence="10" type="ORF">A0J61_01764</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">The glycine cleavage system catalyzes the degradation of glycine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5 7">
            <text>N(6)-[(R)-lipoyl]-L-lysyl-[glycine-cleavage complex H protein] + glycine + H(+) = N(6)-[(R)-S(8)-aminomethyldihydrolipoyl]-L-lysyl-[glycine-cleavage complex H protein] + CO2</text>
            <dbReference type="Rhea" id="RHEA:24304"/>
            <dbReference type="Rhea" id="RHEA-COMP:10494"/>
            <dbReference type="Rhea" id="RHEA-COMP:10495"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:57305"/>
            <dbReference type="ChEBI" id="CHEBI:83099"/>
            <dbReference type="ChEBI" id="CHEBI:83143"/>
            <dbReference type="EC" id="1.4.4.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 6 7">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="7">The glycine cleavage system is composed of four proteins: P, T, L and H.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the GcvP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.4.4.2" evidence="7"/>
    <dbReference type="EMBL" id="LUGH01000060">
        <property type="protein sequence ID" value="OBZ90176.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NNY7"/>
    <dbReference type="FunCoup" id="A0A1C7NNY7">
        <property type="interactions" value="303"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NNY7"/>
    <dbReference type="InParanoid" id="A0A1C7NNY7"/>
    <dbReference type="OrthoDB" id="6537869at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005960">
        <property type="term" value="C:glycine cleavage complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016594">
        <property type="term" value="F:glycine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004375">
        <property type="term" value="F:glycine dehydrogenase (decarboxylating) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019464">
        <property type="term" value="P:glycine decarboxylation via glycine cleavage system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00613">
        <property type="entry name" value="GDC-P"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.640.10:FF:000005">
        <property type="entry name" value="Glycine dehydrogenase (decarboxylating), mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.640.10:FF:000007">
        <property type="entry name" value="glycine dehydrogenase (Decarboxylating), mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.1150.10:FF:000007">
        <property type="entry name" value="Glycine dehydrogenase (decarboxylating), mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00711">
        <property type="entry name" value="GcvP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003437">
        <property type="entry name" value="GcvP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049316">
        <property type="entry name" value="GDC-P_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049315">
        <property type="entry name" value="GDC-P_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020581">
        <property type="entry name" value="GDC_P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00461">
        <property type="entry name" value="gcvP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF001696">
        <property type="entry name" value="PRK00451.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003346">
        <property type="entry name" value="PRK04366.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11773:SF1">
        <property type="entry name" value="GLYCINE DEHYDROGENASE (DECARBOXYLATING), MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11773">
        <property type="entry name" value="GLYCINE DEHYDROGENASE, DECARBOXYLATING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21478">
        <property type="entry name" value="GcvP2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02347">
        <property type="entry name" value="GDC-P"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="4 7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3 6 7" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="Glycine cleavage system P-protein N-terminal" evidence="8">
        <location>
            <begin position="58"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="domain" description="Glycine cleavage system P-protein N-terminal" evidence="8">
        <location>
            <begin position="509"/>
            <end position="782"/>
        </location>
    </feature>
    <feature type="domain" description="Glycine dehydrogenase C-terminal" evidence="9">
        <location>
            <begin position="825"/>
            <end position="945"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="6">
        <location>
            <position position="753"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010756"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00049026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR603437-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU364056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF21478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OBZ90176.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="1003" mass="109961" checksum="B224E5FCD484D8A6" modified="2016-11-30" version="1">MLSRIALRSRGAIARLPAQRFVAQPLRQPSFIAKPCARFQHTSKPALSKIAPLDTFPRRHIGSEGQDVQAMLDQLGVKSIDEMLSKTIPPSIRSPKPLAIGEGIPERELLARLKEVASKNKIARSYIGQGYTDTVVPNVILRNILENPAWYTQYTPYQPEISQGRLESLLNYQTLVTDLTGLPIANASLLDEGTAAAEAMLMCWQAARRKKNLFIVDENCHPQTIACLKTRAESFNINVVVADTLHYNFSEHKDLCGVLLQYPDTRGSVKDYEALTASVHAAGGQVTVATDLMALTLLKAPGEFGADIAFGNSQRFGVPMGFGGPHAAFFSCKDEHKRRMPGRLIGVSKDADGNSAYRLALQTREQHIRREKATSNICTAQALLANMAAMYAVYHGPEGLRSIAQRINNMTSILAQAIRQSGFVIENGNNFFDTLAIKVGNSSSILTKATAAGINLRAIDSGTVGITLDEAVTQDDLVKLIEVFHKEDHPLPSIEELAQSLDINKFTYPDQLERKSAYLTHPVFNTYHSETEMLRYIHHLESKDLSLVHSMIALGSCTMKLNATTEMIPVTWPEFANIHPFAPVEQTEGYLTMLDELADDLKEITGFEGVSLQPNSGAQGEYAGLRVIRAYHHARGETERNVCLIPISAHGTNPASAAMSGMDVVIVQCDSNGNLDMEDLKAKAEKHKDKLAAVMITYPSTFGIFEAGVSEACKIIHDNGGLVYLDGANLNAQIGLTKPAEIGADVCHMNLHKTFCIPHGGGGPGMGPIACTKELEPYLPGHPVVACGGKNPIGPISAAPYGSASILPISWAYIKMMGSEGLTQATKVAILNANYMASRLSEHYNVLYTNENGMCGHEFIVDIRPFVQHGIEAIDVAKRLQDYGFHSPTMSWPVTNTLMIEPTESESKAELDRFCDAMISIRKEIQQVIDGKLPKGDNMLNNAPHSIKALMSDKWNRPYGREVAAFPMPYLKEKKFWPSVSRVDDAYGDRKLICTCPSPEDYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NNZ7</accession>
    <name>A0A1C7NNZ7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein YbeQ</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">ybeQ_4</name>
        <name evidence="1" type="ORF">A0J61_01093</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000031">
        <property type="protein sequence ID" value="OBZ90852.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NNZ7"/>
    <dbReference type="STRING" id="101091.A0A1C7NNZ7"/>
    <dbReference type="InParanoid" id="A0A1C7NNZ7"/>
    <dbReference type="OrthoDB" id="272077at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052945">
        <property type="entry name" value="Mitotic_Regulator"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006597">
        <property type="entry name" value="Sel1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43628">
        <property type="entry name" value="ACTIVATOR OF C KINASE PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43628:SF1">
        <property type="entry name" value="CHITIN SYNTHASE REGULATORY FACTOR 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08238">
        <property type="entry name" value="Sel1"/>
        <property type="match status" value="15"/>
    </dbReference>
    <dbReference type="SMART" id="SM00671">
        <property type="entry name" value="SEL1"/>
        <property type="match status" value="14"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81901">
        <property type="entry name" value="HCP-like"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ90852.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="669" mass="74838" checksum="3C5C3A3A4D3DE862" modified="2016-11-30" version="1">MPSAIPFSAIFSRSKSVFSKFSQHKKQASKPRQRYFSSSDSSLPTTSSYSTQLKTIIDSSVFDNVSAKQLLKRGNDYLFGRNGYQISQELAVAHFIKATNLGSARAEGVLGFCYEFGMGLETDFVQSEYHYLNAAKKNDGLSIARLAFLRKYGRPNVKIDRAEAEEWAERIKGRPNAIKWIFEAASLYHDAAAQYTLGVCYHDGIAVPKDEHAAFRWYKLSADQGNARGQGILGYCYGEGFGVEKNEKIAMKWYRLAASQGETVAIYNIGYCYEDGIGVEKDVNEAVKWYRLSAEQGNAFGQNSLGYCYEDGIGVEEDHAKAAKWYKLSAEQGYPWAECNLGYCYQNGIGLEKDDTLGAYWYRCAALQGHARAQHNLGFCYQNGIGVERNEKEAVKWYRRSAERGNIFAYHSLGYCYQNGIGVPVNEKESVLWYYLSAEENHPPAQLSLGYCYRNGIGVTKNEAEAVKWFRRSAEHGNALAQNSLGFCFEEGIGLKKDPTRAVYWYHKSAKQNNPWAQCNLGFCYANGIGVERDDVKAVEWYQRAAAQNHTRALDKLGVHLQEGRGIERDENAAFELFKKAAQSDHISAQYHLGNCYEKGLGCQVDLSQATYWFERAALAGCRSSHERLRSLIVRECLLSPGNSASMSLASEDDLIYGGLIIGHSAPAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NP14</accession>
    <name>A0A1C7NP14_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Mitochondrial dicarboxylate transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">DIC1_1</name>
        <name evidence="11" type="ORF">A0J61_01071</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000030">
        <property type="protein sequence ID" value="OBZ90871.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NP14"/>
    <dbReference type="STRING" id="101091.A0A1C7NP14"/>
    <dbReference type="InParanoid" id="A0A1C7NP14"/>
    <dbReference type="OrthoDB" id="448427at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031966">
        <property type="term" value="C:mitochondrial membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.50.40.10:FF:000107">
        <property type="entry name" value="Mitochondrial dicarboxylate carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002067">
        <property type="entry name" value="MCP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050391">
        <property type="entry name" value="Mito_Metabolite_Transporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45618">
        <property type="entry name" value="MITOCHONDRIAL DICARBOXYLATE CARRIER-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00784">
        <property type="entry name" value="MTUNCOUPLING"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 9 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 10" id="KW-0813">Transport</keyword>
    <feature type="repeat" description="Solcar" evidence="9">
        <location>
            <begin position="4"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="9">
        <location>
            <begin position="96"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="9">
        <location>
            <begin position="193"/>
            <end position="279"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="OBZ90871.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="295" mass="32477" checksum="E25E5118293D69E5" modified="2016-11-30" version="1">MIKSPFYFGGLASCCAAVIVHPLDLTKVRLQNSRGGQNAGMLHTLLKVVRTEGFLKIYAGLSASILRQATYSTARLGGYDALKQMVLQKNKNPSTWQLLMCSTAAGIVGGICGNPGDVVNVRMQNDGQLPAHVRRNYMHAFDGLARMTREEGLASLFRGVGPNINRAILMTSSQCVSYDRFKASFLDNQLLQEGLGLHLISSILAGLVATTVCSPVDVIKTRIMSATGSEGKLSAFHFMLQMYRSEGVLAFFKGWTPSFMRTGPQTIFTFIFLEQFKKWHSVWHQDSLLSSTIKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NPC4</accession>
    <name>A0A1C7NPC4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="17">Elongation factor 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="17" type="primary">tef3_1</name>
        <name evidence="17" type="ORF">A0J61_02849</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Protein biosynthesis; polypeptide chain elongation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the ABC transporter superfamily. ABCF family. EF3 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000113">
        <property type="protein sequence ID" value="OBZ89104.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NPC4"/>
    <dbReference type="FunCoup" id="A0A1C7NPC4">
        <property type="interactions" value="44"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NPC4"/>
    <dbReference type="InParanoid" id="A0A1C7NPC4"/>
    <dbReference type="OrthoDB" id="2110130at2759"/>
    <dbReference type="UniPathway" id="UPA00345"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd03221">
        <property type="entry name" value="ABCF_EF-3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="CDD" id="cd18626">
        <property type="entry name" value="CD_eEF3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.10.10:FF:000076">
        <property type="entry name" value="Elongation factor 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.990:FF:000002">
        <property type="entry name" value="mRNA export factor elf1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000193">
        <property type="entry name" value="Probable Elongation factor 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.990">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050611">
        <property type="entry name" value="ABCF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016197">
        <property type="entry name" value="Chromo-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000953">
        <property type="entry name" value="Chromo/chromo_shadow_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023780">
        <property type="entry name" value="Chromo_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015688">
        <property type="entry name" value="eEF3_ABC2_chromodomain-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047038">
        <property type="entry name" value="eEF3_chromodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021133">
        <property type="entry name" value="HEAT_type_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19211">
        <property type="entry name" value="ATP-BINDING TRANSPORT PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19211:SF5">
        <property type="entry name" value="ELONGATION FACTOR 3A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00385">
        <property type="entry name" value="Chromo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24984">
        <property type="entry name" value="HEAT_EF3_GNC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24987">
        <property type="entry name" value="HEAT_EF3_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00298">
        <property type="entry name" value="CHROMO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54160">
        <property type="entry name" value="Chromo domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50013">
        <property type="entry name" value="CHROMO_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50077">
        <property type="entry name" value="HEAT_REPEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7 17" id="KW-0251">Elongation factor</keyword>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="10" id="KW-0694">RNA-binding</keyword>
    <feature type="repeat" description="HEAT" evidence="13">
        <location>
            <begin position="210"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="16">
        <location>
            <begin position="476"/>
            <end position="692"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="16">
        <location>
            <begin position="720"/>
            <end position="1040"/>
        </location>
    </feature>
    <feature type="domain" description="Chromo" evidence="15">
        <location>
            <begin position="848"/>
            <end position="879"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="1044"/>
            <end position="1082"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="14">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="14">
        <location>
            <begin position="20"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="14">
        <location>
            <begin position="1047"/>
            <end position="1063"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="14">
        <location>
            <begin position="1064"/>
            <end position="1074"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004815"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022768"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00049360"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50013"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="OBZ89104.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="1082" mass="120291" checksum="EFC4780FD20F1C47" modified="2016-11-30" version="1">MSYIGDTSTAAGAAKSADRSKRRSLAALQKPKRVRIGEKESEESKQILNNLLASTDLEERKKLAEEAAGFAHHYGVRAMKACHIFPAISTELFAKKMRSPQILGALELTQSLITSNALLRGQLEPHLITLLTPLLDLQAAKDKAVAELAGQVARNLVKAFNPIATRYIISFCLEGLENSKKWQTKMLSLELIEVLTQVNPMQVLSSLPDLIPVVSDCMWDTKSDVKAAATQCMTTTTALLDNKDIERFIPAVIECINKPESVPETIHQLGATTFVQEVDSGTLALMVPLLGRGLRERQTPIKRKSALIIDNMCKLVDDPEVAAPFLPLLLPALEHVHETVADPECRGVVKKAVDTLKRVGGGGTTVLSVDEKREKVEHTLDKLLPTKLEGFFAPVRKYMAKLALALVLARDYDRNAWVSSITPHAATWLLVTGRETEDGGEECEASAEKLALAALSSCEEAIAPKSGEQEEEEEGEELCNCEFSLAYGAKILLNRTHLRLMRGRRYGLCGANGCGKSTLMRAIANEQVEGFPPRSVLKTVYVEHDIDGSEADTGLVDFIISSEGVECQDRQEVARILKNYGFTEEMVHHQAIGSLSGGWKMKLALARAMLMNADILLLDEPTNHLDVVNVAWLENYLLGLKTVTSIIVSHDSGFLDHVCTDIIHYEGNYKLKRYRGNLSEFVKKVPRAAAYYSLGAAQTVFRFPEPGYLEGIKTKERAILKMKNVDFQYPGTAKKQLNDISFQCSLASRVAVIGPNGAGKSTLIKLLTGELESEVGTVWKHPNLRIAYVAQHAFHHIEKHLDSTPNEYIQWRYATGEDREELDKNDRMNAESNKKVMEQTFVIDGEKRVVEDIVGRRKLKQSYEYEVSWVGRSSVDNTWISRQKLEDMGFGKKIAEVDSAEAAKMGLLRPLTAKEIEKHLEEVGLEPEFASHSHIRGLSGGQKVKLVIGAAMWNKPHMLVLDEPTNYLDRESLGALANAIREYGGGVVIVTHNREFSEALCNEVWKVDNGYLTPSGHNWVSGQGTTAIKEEEQEDMVDAQGNTVKAVQKKKKLTSKELRKKKKERMERRKRGEEVYTTDEEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NPE5</accession>
    <name>A0A1C7NPE5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Short-chain-enoyl-CoA hydratase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">crt</name>
        <name evidence="1" type="ORF">A0J61_01082</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000031">
        <property type="protein sequence ID" value="OBZ90860.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NPE5"/>
    <dbReference type="STRING" id="101091.A0A1C7NPE5"/>
    <dbReference type="InParanoid" id="A0A1C7NPE5"/>
    <dbReference type="OrthoDB" id="2018133at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006635">
        <property type="term" value="P:fatty acid beta-oxidation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06558">
        <property type="entry name" value="crotonase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.226.10">
        <property type="entry name" value="2-enoyl-CoA Hydratase, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001753">
        <property type="entry name" value="Enoyl-CoA_hydra/iso"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11941:SF158">
        <property type="entry name" value="ENOYL-COA HYDRATASE (AFU_ORTHOLOGUE AFUA_2G10650)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11941">
        <property type="entry name" value="ENOYL-COA HYDRATASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00378">
        <property type="entry name" value="ECH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="ClpP/crotonase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ90860.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="277" mass="30089" checksum="B6884B5B57D9B1C8" modified="2016-11-30" version="1">MQLPKTEFTLLSIPEPHILLITINRVKQYNALSPAANWELHHLFNWAEEQDDIWCIIIDKLTGAGGKAFCSGMDLVSAHNAHSSEQSDVKGMPPTGFGGLSNRRMSRKPVIAAVNGFALGGGMEMACSCNMVIATERSQFGFPEVKQSVVIAAGGLARLARSVSYQVASELVLTGRFISAQEAKQHGLVNQIIANDANVVDAAIGWAKKMTANSPDAVLLTKQGLLLALERPSMTDATDEWMATPEAEAWRQGYNLGEGLKAFAEKRKPQWKNPSKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NRK3</accession>
    <name>A0A1C7NRK3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_00376</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000008">
        <property type="protein sequence ID" value="OBZ91569.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NRK3"/>
    <dbReference type="STRING" id="101091.A0A1C7NRK3"/>
    <dbReference type="InParanoid" id="A0A1C7NRK3"/>
    <dbReference type="OrthoDB" id="2289236at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004672">
        <property type="term" value="F:protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24362:SF309">
        <property type="entry name" value="PROTEIN KINASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24362">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE NEK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="346"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="2">
        <location>
            <begin position="484"/>
            <end position="758"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ91569.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="762" mass="85200" checksum="BAAE3506D7216AC9" modified="2016-11-30" version="1">MQPSVLFNISNNNGFSFQGLCTYADDSSSFYLDFKNDKLNTSQIYQLEANQSPELKETSVTFSKTNLFSIQYIRDAINQPQLAYVATQSTQQKIFGIANILKPTPNYKNITELGTLAATNTLTSKNLYLLQNNSIEIYRLAEKQYNHATISSGLFSTYQSSASGPILVNSSMEYIPLYEPTTGTLKILAHNTSLTAYSKLPLINDQISLNDQNIQTPSSTIVRSTSTIEAVPKMGATPIADPKKRRLYSKRSVTMTTEDESMQSKAYSLKSYKVTNVDSELSPNAIFLQSSTANTGSTNSIPYEFGTIVLGGNNTATISIQRESSSPSPSVSTVIPETNSSHQSGLSAGAIAGIVLGSVAFLLISAVLLLCMKRRRSKKQRKLKTREMLKAYCGSKDFKGDTLLPSNLQQLHETGSKNSYSYSTAGIQDMKDILDDARPNIQPLCYTRDAIDYAELPEQELAQLEPDVKGPLYLFNGLYVSPESEQVNHVMDGYVTRTFRSEDGNKHTMHYFSTSHAHTFIRSVYAALRISLPGKATYTIKSERAIVLGSPTPHSNYQYIWISSPVMADHSLHHLLFENNVWSFIDYHSSDYKIWSVYALLKSIESVHDQDFVHLAIEPKSFYFDHEMNATDWHLGNFSHTHALSNQQHPSLPIPTPYSAPELIENDKSFAFIEKSSDIWSLGCVIYTVATDGLVLFSSVEQVRELLKANIIDQHIEKAIQGTIENNAFVKILSMMLRANANERKMINEIVAYWHSVYNMEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NRN3</accession>
    <name>A0A1C7NRN3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">30S ribosomal protein S12</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">rpsL</name>
        <name evidence="4" type="ORF">A0J61_00361</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uS12 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000007">
        <property type="protein sequence ID" value="OBZ91599.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NRN3"/>
    <dbReference type="FunCoup" id="A0A1C7NRN3">
        <property type="interactions" value="226"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NRN3"/>
    <dbReference type="InParanoid" id="A0A1C7NRN3"/>
    <dbReference type="OrthoDB" id="361013at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015935">
        <property type="term" value="C:small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03368">
        <property type="entry name" value="Ribosomal_S12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.140:FF:000099">
        <property type="entry name" value="Ribosomal protein S12, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00403_B">
        <property type="entry name" value="Ribosomal_uS12_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006032">
        <property type="entry name" value="Ribosomal_uS12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005679">
        <property type="entry name" value="Ribosomal_uS12_bac"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00981">
        <property type="entry name" value="rpsL_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11652">
        <property type="entry name" value="30S RIBOSOMAL PROTEIN S12 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00164">
        <property type="entry name" value="Ribosom_S12_S23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01034">
        <property type="entry name" value="RIBOSOMALS12"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00055">
        <property type="entry name" value="RIBOSOMAL_S12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005657"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OBZ91599.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="176" mass="19448" checksum="F0D4B4FEB3FC5DC7" modified="2016-11-30" version="1">MQAFCSLLKTAWKPLTNNVISSRSLMTQNSSILSQLKPTNWTPIYQQQKAGMATLNQVIKKCRKSKAKLSKTPALEGCYQRKGVCNKVYTTKPKKPNSAVRKVARVKLTNGKVVTAYIPGEGHNLQEHSVVLVRGGRVPDLPGVRYHLVRGALDLQGVATRTTSRSKYGTKKPSKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NRQ7</accession>
    <name>A0A1C7NRQ7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="8">60S ribosomal protein L5-A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">rpl5a_1</name>
        <name evidence="8" type="ORF">A0J61_00149</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the universal ribosomal protein uL18 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000003">
        <property type="protein sequence ID" value="OBZ91815.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NRQ7"/>
    <dbReference type="FunCoup" id="A0A1C7NRQ7">
        <property type="interactions" value="584"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NRQ7"/>
    <dbReference type="InParanoid" id="A0A1C7NRQ7"/>
    <dbReference type="OrthoDB" id="1618453at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022625">
        <property type="term" value="C:cytosolic large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008097">
        <property type="term" value="F:5S rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000027">
        <property type="term" value="P:ribosomal large subunit assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00432">
        <property type="entry name" value="Ribosomal_L18_L5e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.100:FF:000002">
        <property type="entry name" value="60S ribosomal protein L5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01337_A">
        <property type="entry name" value="Ribosomal_uL18_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005485">
        <property type="entry name" value="Rbsml_uL18_euk_arch"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057268">
        <property type="entry name" value="Ribosomal_L18"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025607">
        <property type="entry name" value="Ribosomal_uL18_C_euk"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23410:SF12">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN UL18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23410">
        <property type="entry name" value="RIBOSOMAL PROTEIN L5-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14204">
        <property type="entry name" value="Ribosomal_L18_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17144">
        <property type="entry name" value="Ribosomal_L5e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00058">
        <property type="entry name" value="RIBOSOMALL5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53137">
        <property type="entry name" value="Translational machinery components"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4 8" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Large ribosomal subunit protein uL18 C-terminal eukaryotes" evidence="7">
        <location>
            <begin position="236"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="245"/>
            <end position="268"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007116"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF14204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OBZ91815.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="292" mass="33249" checksum="85885FAE23EB9328" modified="2016-11-30" version="1">MPFVKQQKNKAYFKRYQVKYRRRREGKTDYYARKRLVVQAKNKYNSPKYRLVVRFTNKDIICQIIYAKLQGDHVLSAAYAHELPRYGVKGGLTNWASAYATGLLLARRTLTKLGLADKYEGFAEPDGTVQLIEAAEDAPRPFKAFLDVGLARTSTGARVFGAMKGASDGGIFVPHSGNRFPGFDIESKTNDDELLRNYIYGVHVAEYMEYLEEEDEERYKKQFSTFIKNGITSDMVEDMYTEAHEAIRADPSPKPTEKKGKPAKPYRRATALNKKQRVNKVKEAKAAFDAAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NRW1</accession>
    <name>A0A1C7NRW1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Myocyte-specific enhancer factor 2D</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">mef2d_1</name>
        <name evidence="9" type="ORF">A0J61_00070</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the MEF2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000002">
        <property type="protein sequence ID" value="OBZ91871.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NRW1"/>
    <dbReference type="STRING" id="101091.A0A1C7NRW1"/>
    <dbReference type="InParanoid" id="A0A1C7NRW1"/>
    <dbReference type="OrthoDB" id="1898716at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00265">
        <property type="entry name" value="MADS_MEF2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1810.10">
        <property type="entry name" value="Transcription factor, MADS-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033896">
        <property type="entry name" value="MEF2-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002100">
        <property type="entry name" value="TF_MADSbox"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036879">
        <property type="entry name" value="TF_MADSbox_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11945">
        <property type="entry name" value="MADS BOX PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11945:SF534">
        <property type="entry name" value="MYOCYTE-SPECIFIC ENHANCER FACTOR 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00319">
        <property type="entry name" value="SRF-TF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00404">
        <property type="entry name" value="MADSDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00432">
        <property type="entry name" value="MADS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55455">
        <property type="entry name" value="SRF-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50066">
        <property type="entry name" value="MADS_BOX_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="MADS-box" evidence="8">
        <location>
            <begin position="1"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="98"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="225"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="121"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="239"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="276"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="294"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="352"/>
            <end position="361"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00025805"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50066"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OBZ91871.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="381" mass="43597" checksum="EB3AC653E1DCB6FD" modified="2016-11-30" version="1">MGRKKIRIQPITDDRNRQVTFLKRKHGLMKKAYELSVLCNCEIALIILNNSNNKLVQYASTDIDKVLMRYTEVAFVIGCFIVLLTYYDEPYESKSNGDFVNSSEKGEEDNFQDFSDHEETPQPQSQSQQPQQKPMDYNVMNYTSERTPMTQHPSVSQAMQNYELYPMYMDLFANLIHIKQKPNSSYAQSRPIMYTPSPQTQPMMLPSGNMTYPSPPQPASFYHVKEQQQLPPTPPVPQSIASPKSTSELDSESYKRPHLRVQIPSEESPKQATDRLPQSTTRSQKSALGPPSFLPSQFAQNLPSPSTFYPEFYQQNELPSPLNFSATPTNPNTFHWPSNARDYRPSPLSNTRFDESTEKRQAPTGYENPHTKKMKMQPTAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NS78</accession>
    <name>A0A1C7NS78_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Phosphatidylinositol transfer protein CSR1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">CSR1_1</name>
        <name evidence="3" type="ORF">A0J61_00125</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000002">
        <property type="protein sequence ID" value="OBZ91839.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NS78"/>
    <dbReference type="STRING" id="101091.A0A1C7NS78"/>
    <dbReference type="InParanoid" id="A0A1C7NS78"/>
    <dbReference type="OrthoDB" id="75724at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00170">
        <property type="entry name" value="SEC14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.525.10">
        <property type="entry name" value="CRAL-TRIO lipid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001251">
        <property type="entry name" value="CRAL-TRIO_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036865">
        <property type="entry name" value="CRAL-TRIO_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036273">
        <property type="entry name" value="CRAL/TRIO_N_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052432">
        <property type="entry name" value="PITP/CRAL-TRIO"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46590:SF4">
        <property type="entry name" value="CRAL-TRIO DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46590">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL TRANSFER PROTEIN CSR1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00650">
        <property type="entry name" value="CRAL_TRIO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00516">
        <property type="entry name" value="SEC14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52087">
        <property type="entry name" value="CRAL/TRIO domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46938">
        <property type="entry name" value="CRAL/TRIO N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50191">
        <property type="entry name" value="CRAL_TRIO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CRAL-TRIO" evidence="2">
        <location>
            <begin position="95"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="278"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="342"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="278"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="292"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="346"/>
            <end position="355"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ91839.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="597" mass="67356" checksum="4545DAECC551D797" modified="2016-11-30" version="1">MSLQDQERFSTIDSQYKENKETIQKLFSQITNDLTQLNLSDKELSDTHAYLEDKVNLFRFLRTSKFDVTKAAQRVLATIQWRIKTGIVDLTLKDCMDFYQQDAFAYYHGHDTFGRPLIFVRAKYFPKQFADNTQSITSVVRPYACLMMEIARQLTWKMTCDREAKGEPVITQITVIADITQAPFIPVTPELIRTMSDILEERYPDTVNSINVLNFSWVYQGIWSVMKHLLNQEAKDSIRFTTINELEPLVPANQIPEEMGGLNGEVWSLESDEILQTYGSLNPPTQVPHTPLLSNTQSRTSSTSSDSAGLISHPSIRSESDSDIFFDATDNLSIVSVPREKLATPTRPPIQPFPPATITESPPSPPMSPTKNTSKVEVPYQIIDSIAPNEAIVPLNEPISSEPPHNNLALHSQTDSNSPHHYIQSATAGLHTGNQFMTSLVNPRAAHEIIPLTTSFNRSHRSSSIIVVEPDLRDKVIREAAARDKAYLTRNHQYHHQDALYQLPVISFQRIASWMSNVTHQIIQISFGPANGVMYWACIYVLMRGPAENTIRRILERTQWITEPNKLSRVTIGVTAALAATMSSSLSNTLERIRNSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NSB9</accession>
    <name>A0A1C7NSB9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="13">E3 SUMO-protein ligase MMS21</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">MMS21</name>
        <name evidence="13" type="ORF">A0J61_00022</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="2">Protein modification; protein sumoylation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the NSE2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000001">
        <property type="protein sequence ID" value="OBZ91919.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NSB9"/>
    <dbReference type="FunCoup" id="A0A1C7NSB9">
        <property type="interactions" value="148"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NSB9"/>
    <dbReference type="InParanoid" id="A0A1C7NSB9"/>
    <dbReference type="OrthoDB" id="26899at2759"/>
    <dbReference type="UniPathway" id="UPA00886"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030915">
        <property type="term" value="C:Smc5-Smc6 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061665">
        <property type="term" value="F:SUMO ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000724">
        <property type="term" value="P:double-strand break repair via homologous recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016925">
        <property type="term" value="P:protein sumoylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd16651">
        <property type="entry name" value="SPL-RING_NSE2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026846">
        <property type="entry name" value="Nse2(Mms21)"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004181">
        <property type="entry name" value="Znf_MIZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21330">
        <property type="entry name" value="E3 SUMO-PROTEIN LIGASE NSE2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21330:SF1">
        <property type="entry name" value="E3 SUMO-PROTEIN LIGASE NSE2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11789">
        <property type="entry name" value="zf-Nse"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51044">
        <property type="entry name" value="ZF_SP_RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="13" id="KW-0436">Ligase</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="7" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="8" id="KW-0862">Zinc</keyword>
    <keyword evidence="6 10" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="SP-RING-type" evidence="12">
        <location>
            <begin position="156"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="233"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="233"/>
            <end position="243"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004718"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00452"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51044"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="OBZ91919.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="252" mass="29113" checksum="1CDFC19B3AC9CBC5" modified="2016-11-30" version="1">MSDRETTLEDIRDNFSFDSRNSSIFSNVTGDIRDLQLLIQKGQGHIKTAAEDHEESKRTEKVAALDERFKRLIDLSNELHCHKNTMDQLKTRIDRGEKVKDIAGHYEKEKDVQSNKIAADESKKFYRNNSYVAFRQLLWTIHHPDEEMPSLVETTEEDDIVMGPSKISLKCPLTTIWFEDPMTSIICKHTFSKSAIFSLFKHQNAIPCPIPGCNRPVQRASLKPDDLMAERVKRAKEREKEGQKATQFFDVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NSJ2</accession>
    <name>A0A1C7NSJ2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Putative pseudouridine synthase C1A4.09</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">SPBC1A4.09</name>
        <name evidence="5" type="ORF">A0J61_00296</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the pseudouridine synthase TruD family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000006">
        <property type="protein sequence ID" value="OBZ91646.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NSJ2"/>
    <dbReference type="FunCoup" id="A0A1C7NSJ2">
        <property type="interactions" value="879"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NSJ2"/>
    <dbReference type="InParanoid" id="A0A1C7NSJ2"/>
    <dbReference type="OrthoDB" id="447290at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031429">
        <property type="term" value="C:box H/ACA snoRNP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009982">
        <property type="term" value="F:pseudouridine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000455">
        <property type="term" value="P:enzyme-directed rRNA pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990481">
        <property type="term" value="P:mRNA pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031120">
        <property type="term" value="P:snRNA pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031119">
        <property type="term" value="P:tRNA pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd02576">
        <property type="entry name" value="PseudoU_synth_ScPUS7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2350.20">
        <property type="entry name" value="TruD, catalytic domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01082">
        <property type="entry name" value="TruD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020103">
        <property type="entry name" value="PsdUridine_synth_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001656">
        <property type="entry name" value="PsdUridine_synth_TruD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020119">
        <property type="entry name" value="PsdUridine_synth_TruD_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011760">
        <property type="entry name" value="PsdUridine_synth_TruD_insert"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042214">
        <property type="entry name" value="TruD_catalytic"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00094">
        <property type="entry name" value="tRNA_TruD_broad"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13326:SF21">
        <property type="entry name" value="PSEUDOURIDYLATE SYNTHASE PUS7L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13326">
        <property type="entry name" value="TRNA PSEUDOURIDINE SYNTHASE D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01142">
        <property type="entry name" value="TruD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037016">
        <property type="entry name" value="Pseudouridin_synth_euk_prd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55120">
        <property type="entry name" value="Pseudouridine synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50984">
        <property type="entry name" value="TRUD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01268">
        <property type="entry name" value="UPF0024"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0413">Isomerase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="TRUD" evidence="4">
        <location>
            <begin position="308"/>
            <end position="538"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007953"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OBZ91646.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="616" mass="69933" checksum="96D007D1959B21A3" modified="2016-11-30" version="1">MGNLFSKTTSEEIESGRKRALEFDAVEDSKKARVDRVIIKESEVGIVAYVNQDIKGFHSILKFRAEDFLVNEVDMDKNIVRLTSLAPPDTKVDKNIAYDFYEPSIFDQAVSEIFDKGFAELFRCFLNTPEEADAVLTTQASKEQRLEFYRLVEEHLEAKVNCRGKDGSLVVRWPSSTHSDEFIDWKALGGDYLQVNMQKSGVDTMNAINIISKKIGVHAKNFGYAGTKDAKAITTQSLTLKSVKPGRIVMAQEDLKKSNIYIGDFKFVPNGLTLGDLNGNHFTIVLRDVKGANEEELEVSLQSLKQNGFLNYFGMQRFGTSVVSTHTIGCAIMKKKFEEASDLILNPREGERPEYHNARKLWQDTHDAESVLPIFPKRAFSERKLLTFYARHPGNHSKAIKSLPKNMLSLYSHAYQSYIWNRVVSERAKLFGTDRPMVGDLVLVDNKPQAAKSKRVNNNVGRRDPNNRKVPKILTAEDLDEYSIFDVVYPLPGRQTVYPENEIKEIYRKFLAEDGISIEKKDNHFDSLTGDYRAMLSKPEQMSWSFIRYDDPTEKLCNTDVDKLENAPEPMGIEDGKYLALKVEFTLGTSQYATMALREIMRAETSSQAQSSIVHD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7LQE7</accession>
    <name>A0A1C7LQE7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_11950</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01002748">
        <property type="protein sequence ID" value="OBZ65004.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7LQE7"/>
    <dbReference type="STRING" id="101091.A0A1C7LQE7"/>
    <dbReference type="InParanoid" id="A0A1C7LQE7"/>
    <dbReference type="OrthoDB" id="2289822at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="82"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="192"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ65004.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="192" mass="22127" checksum="13121070EFB2ABD0" modified="2016-11-30" version="1" fragment="single">MIEVQASSMPDILVGEFKNVLLPSQRLRGVDWSVFIQFILPTLVVEQIELQQFNRVPKKKLDENFTINQHYLEHLPKDAKEVGLAQTNCVSLERRIQELKRKIKSTRKVEENAANVIVKAANKNFIRRSKIVYRDEDTMDVKLSFCHAANINSFDAYKLKPLLAEAIGTNLQDISSIINYATTVKFLKKVFY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-06-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7LV07</accession>
    <name>A0A1C7LV07_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_11914</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01002685">
        <property type="protein sequence ID" value="OBZ66674.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7LV07"/>
    <dbReference type="InParanoid" id="A0A1C7LV07"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ66674.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="161" mass="18179" checksum="655E237956811CB1" modified="2016-11-30" version="1" fragment="single">DRQAITQQFADIKSGQAPGLSELEENARAFNNTIRAQNDTSDHLKYHIFKLAEYSQHLKEEYSCHLVIIHFTCRDGYPDDYGCYAKSEAGKLLQRQIYSGLGNHMVQVVFTKLLTALSHDLKLAARGVSRDDVVASAFIALKKLQVDSFESLEISDGWKQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MTH6</accession>
    <name>A0A1C7MTH6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Reverse transcriptase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_11780</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01002476">
        <property type="protein sequence ID" value="OBZ80171.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MTH6"/>
    <dbReference type="InParanoid" id="A0A1C7MTH6"/>
    <dbReference type="OrthoDB" id="2426083at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ80171.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="210" mass="24152" checksum="C704F7A9092DC88A" modified="2016-11-30" version="1" fragment="single">VFLRNHRDLDHLLSAIHTYSSASNAHLNFHKTEAISLSGQPLPQWQQPLQSRNIFSWHDRHSPFPFIHLGFPIIFSLKQCSIAFEKLETTFSSACNIHSQRNLSVRGRATVLNTLIFSKLSHVLRLTTFPQQQIHRLLSIGSRFINHHIFPPLSLATLRLPRKQGGLQVLNLISQQQALQWRWASTLLHSSSPSNSLSPASFLRYTFEWF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MTK1</accession>
    <name>A0A1C7MTK1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_11779</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01002472">
        <property type="protein sequence ID" value="OBZ80172.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MTK1"/>
    <dbReference type="STRING" id="101091.A0A1C7MTK1"/>
    <dbReference type="InParanoid" id="A0A1C7MTK1"/>
    <dbReference type="OrthoDB" id="2289822at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ80172.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="109" mass="12509" checksum="6CEF4F40B408BE22" modified="2016-11-30" version="1">MESGQNCASWYVGEVITYFIHSYHGSSKFLALISVVESSTLEEYGVPSITLFHEDSPQKKYMVCDVEDITNIVGFVRYNENVLQHRLIWPDAMHHKKIDNLKKGELGNM</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MTQ4</accession>
    <name>A0A1C7MTQ4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_11804</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01002515">
        <property type="protein sequence ID" value="OBZ80147.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MTQ4"/>
    <dbReference type="InParanoid" id="A0A1C7MTQ4"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ80147.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="60" mass="6635" checksum="F6592FA55321673A" modified="2016-11-30" version="1">MDSPLLSQVSQSISDTVCMSRGRSDTYPSVSDEETVGEKRPAEEEDDNTSNKTSRTDDSY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MTW8</accession>
    <name>A0A1C7MTW8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_11744</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01002419">
        <property type="protein sequence ID" value="OBZ80207.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="InParanoid" id="A0A1C7MTW8"/>
    <dbReference type="OrthoDB" id="2293388at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ80207.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="218" mass="25072" checksum="24769C0A7477A751" modified="2016-11-30" version="1">MMYSSDFDDEVVHDKRVSCPQVEEKLVVGVEEDVVASPGPFPMQGISFLNKSENLFANADKEPVTAAIFAAEVFRPTPLEPKEPYQGMVIKGRAQRWYRRQGLSVHSPVKQQAKKRSQTEKTHAKFAKWLSDYKDLVKKRDEMISKGTRFHHDIVLEIVKYCQHLNEEPTTQRSFDSYQTRRADVVKSLLRNHSLIYPVVMKAVRKADPXSRSGPFDH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MUZ1</accession>
    <name>A0A1C7MUZ1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Endonuclease/exonuclease/phosphatase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_11289</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001872">
        <property type="protein sequence ID" value="OBZ80662.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MUZ1"/>
    <dbReference type="InParanoid" id="A0A1C7MUZ1"/>
    <dbReference type="OrthoDB" id="2443300at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.10.10">
        <property type="entry name" value="Endonuclease/exonuclease/phosphatase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036691">
        <property type="entry name" value="Endo/exonu/phosph_ase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005135">
        <property type="entry name" value="Endo/exonuclease/phosphatase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03372">
        <property type="entry name" value="Exo_endo_phos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56219">
        <property type="entry name" value="DNase I-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Endonuclease/exonuclease/phosphatase" evidence="1">
        <location>
            <begin position="9"/>
            <end position="127"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03372"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ80662.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="350" mass="39517" checksum="EBDA8C0C02DA1295" modified="2016-11-30" version="1">MSVSTITIATLNCRGLRETHNPSSSRSFIRYLRSLNIDILCLQETHTIDTTIQAEFDLLFNTTSSLWTTNCGDLNINPMQKSNITDVWLELLDLRFRDCFGQTFQPTFTSTTGSRTRIDFIFSSADHHLSITFTAQEFLSSAWTDHDLLAATFRPILESNGPGLWKANSFLANLPSFRHGLIQHIEAFLNSQNVQDGKYPDTPQSFCDTLKAEAKPYTKSYQLETNLWRKKTLKKYQSKRNRILREYKNTTILSSLLPTLEAMIGSFQDEIAHVNALKTGKFWREKGERSAGLLKHLASSRTMQRTISSLYDTSTEQLVTTVLSCAGGSTFTRSALATTPETPTYHSPIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MV40</accession>
    <name>A0A1C7MV40_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_11655</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01002306">
        <property type="protein sequence ID" value="OBZ80296.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MV40"/>
    <dbReference type="InParanoid" id="A0A1C7MV40"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ80296.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="114" mass="13084" checksum="98BE01D0EFBDA73C" modified="2016-11-30" version="1">MFGKHLCHNCSQLFTLKALIQHMNECVVNVAEEQETVVPEKRRKVEEANHQSMEGLLDNSNSFDFEGCEVNEAPAQKETAGVFGESIKRQYVLPNDDNCIEIMDKKNKEFHEIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MV51</accession>
    <name>A0A1C7MV51_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transposon TX1 uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">YTX2_5</name>
        <name evidence="2" type="ORF">A0J61_11251</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001831">
        <property type="protein sequence ID" value="OBZ80700.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MV51"/>
    <dbReference type="STRING" id="101091.A0A1C7MV51"/>
    <dbReference type="InParanoid" id="A0A1C7MV51"/>
    <dbReference type="OrthoDB" id="2213994at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01650">
        <property type="entry name" value="RT_nLTR_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043502">
        <property type="entry name" value="DNA/RNA_pol_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000477">
        <property type="entry name" value="RT_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19446">
        <property type="entry name" value="REVERSE TRANSCRIPTASES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00078">
        <property type="entry name" value="RVT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56672">
        <property type="entry name" value="DNA/RNA polymerases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50878">
        <property type="entry name" value="RT_POL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Reverse transcriptase" evidence="1">
        <location>
            <begin position="198"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ80700.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="409" mass="45320" checksum="935BCDC52B1B5A18" modified="2016-11-30" version="1" fragment="single">AFSLARAESLLQRKRAKIESNLMNNPSLYPCLSPQLHIVQEQLTSVQQYHVETLSLKAGIRWREQGELSARYLKRTASARLIKTTIPPLFCPTLERVCVSKDEMLDAAFVFYDNLFAPDPIGLNAEDSLLEAIPQSYVLFADDSSLLTDSISFDKIVEAFSRCPKQGSPGLDGLPYSIVRLIVLHPDCKNIVVQVYNDALKFGVFPPSWLSTSVCLLPKKGDLSDLRNWRSISLINTDAKVFTRILNSRFLMVTDQMINPYQSGFVRGRFIADNGLLMKLLMEHVGTSNSSAIALLLDQEKAYDRVHPLYLQLVLEKFGFPSAIVHSITSLFFSTQLSLNINRSHSALVLQRGGLRQGDSLSPILFNLAFEPLLRSILCHTSISGLTLPAPLTPASCLGSGSFQTAASV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MVK4</accession>
    <name>A0A1C7MVK4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_11090</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001664">
        <property type="protein sequence ID" value="OBZ80862.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MVK4"/>
    <dbReference type="STRING" id="101091.A0A1C7MVK4"/>
    <dbReference type="InParanoid" id="A0A1C7MVK4"/>
    <dbReference type="OrthoDB" id="2256709at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ80862.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="176" mass="20346" checksum="A5F3900A8F43C680" modified="2016-11-30" version="1">MTPDEEMQQMPAATSDPVDDLQSHLHPFGIYLRFDWTPDLLVQDQFALDRDLFNNEVLLDEARGELIDKYPPIRQLNYQPPLTMPEAKRHILASEICTTDLPNDHSQRFIEIINDIRSLMLNINANVSSSRTEIAFRAINPSFRAPSTSNQNYLMSWEAFQSACRIQADMSDYSYF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MWC3</accession>
    <name>A0A1C7MWC3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_10844</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001437">
        <property type="protein sequence ID" value="OBZ81107.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MWC3"/>
    <dbReference type="STRING" id="101091.A0A1C7MWC3"/>
    <dbReference type="InParanoid" id="A0A1C7MWC3"/>
    <dbReference type="OrthoDB" id="66964at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="135"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ81107.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="135" mass="16083" checksum="93DB213245A47FB8" modified="2016-11-30" version="1" fragment="single">MTDQPSNEQVKYFENEILMTELKKLEYDIDSSSIPVEVLLQEAIELKYKKINEFMQVSSIDSVQKLKQQLKTDKQTLMEKRLIVEGKVKKYIRTVLQTLDIIWSIIEQFKYKDQKCRNIAFDEYYTSLVDTMLVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MX38</accession>
    <name>A0A1C7MX38_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_10565</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001238">
        <property type="protein sequence ID" value="OBZ81387.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MX38"/>
    <dbReference type="STRING" id="101091.A0A1C7MX38"/>
    <dbReference type="InParanoid" id="A0A1C7MX38"/>
    <dbReference type="OrthoDB" id="2271291at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ81387.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="162" mass="18428" checksum="E57263680DA3891A" modified="2016-11-30" version="1">MEVIGLCVCVCFGAAAHYTGLYIRLTKLPRVEILNMDKLEEVELQTTYYDALLSELIADQDKNVALRWPNKSTDEEQTDIHPHAIVSTIMQHDFGHPVNFRDEKPGNSSKTRHSVSLDVLHLGIASKRAIDKWKLNSCFGFMINEFDLTFFVTKKNNTKIAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MXH2</accession>
    <name>A0A1C7MXH2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_10427</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001169">
        <property type="protein sequence ID" value="OBZ81522.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MXH2"/>
    <dbReference type="InParanoid" id="A0A1C7MXH2"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ81522.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="65" mass="7645" checksum="9B525FDA89A6A301" modified="2016-11-30" version="1" fragment="single">MTLQQLQELMHRLNPFVAIFKNMTQIANDQRNTTNSQSNGIESLENLKLVFRAEGVPDRRRYNRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MYH0</accession>
    <name>A0A1C7MYH0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Mitochondrial aspartate-glutamate transporter AGC1</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="14">Aspartate-glutamate carrier 1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="17" type="primary">aralar1</name>
        <name evidence="17" type="ORF">A0J61_10502</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Calcium-dependent mitochondrial aspartate and glutamate carrier. Transport of glutamate in mitochondria is required for mitochondrial transamination reactions and ornithine synthesis. Plays also a role in malate-aspartate NADH shuttle, which is critical for growth on acetate and fatty acids.</text>
    </comment>
    <comment type="subunit">
        <text evidence="11">Homodimer (via N-terminus).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001203">
        <property type="protein sequence ID" value="OBZ81449.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MYH0"/>
    <dbReference type="STRING" id="101091.A0A1C7MYH0"/>
    <dbReference type="InParanoid" id="A0A1C7MYH0"/>
    <dbReference type="OrthoDB" id="2161at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005471">
        <property type="term" value="F:ATP:ADP antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015183">
        <property type="term" value="F:L-aspartate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005313">
        <property type="term" value="F:L-glutamate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043490">
        <property type="term" value="P:malate-aspartate shuttle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140021">
        <property type="term" value="P:mitochondrial ADP transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990544">
        <property type="term" value="P:mitochondrial ATP transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.50.40.10:FF:000004">
        <property type="entry name" value="Calcium-binding mitochondrial carrier protein Aralar1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002113">
        <property type="entry name" value="ADT_euk_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002067">
        <property type="entry name" value="MCP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051028">
        <property type="entry name" value="Mito_Solute_Carrier"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45678:SF9">
        <property type="entry name" value="CALCIUM-BINDING MITOCHONDRIAL CARRIER PROTEIN ARALAR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45678">
        <property type="entry name" value="MITOCHONDRIAL 2-OXODICARBOXYLATE CARRIER 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13833">
        <property type="entry name" value="EF-hand_8"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00927">
        <property type="entry name" value="ADPTRNSLCASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00926">
        <property type="entry name" value="MITOCARRIER"/>
    </dbReference>
    <dbReference type="SMART" id="SM00054">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0106">Calcium</keyword>
    <keyword evidence="10 15" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 15" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="EF-hand" evidence="16">
        <location>
            <begin position="82"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="16">
        <location>
            <begin position="154"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="15">
        <location>
            <begin position="328"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="15">
        <location>
            <begin position="427"/>
            <end position="518"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="15">
        <location>
            <begin position="528"/>
            <end position="616"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00038674"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00059916"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00073787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00082232"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="OBZ81449.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="675" mass="75780" checksum="DB74A22E5284B110" modified="2016-11-30" version="1">MTDSVSRLEQCRRTFQKYASIENEQKEKFMTRDDFLSAVVPGEDFKKIQREQFELLYRIADRANKGAISFDDFVIFEDLLSKPDAEYEVAFRVFDVEGTGKVTFDQFKSVLSSNMPADAVPFDFDCDWLKLYIGSKEGHHELSYQEFTQLIKGLQGERLRQEFKHYDKDQSGYIAPEDFKKIILDVAKHKLSDDVIDHLPTLCNLTSGNKISFSSVVAFHNVIRNIDMVELVIRKAIENSPDQKITKTDFMKYAHEASRYTAFTPMEADVVFHFAGVDDDSGVLGLDDFARILDPRWTTSHKDLNEKSEKLHLDHPQQPRHGALWQIVESAYSFTLGSIAGAVGATAVYPIDLVKTRMQNQRSKVVGELLYKNSLDCFKKVVKNEGFAGLYRGLGPQLVGVAPEKAIKLTVNDFVRSQFTSKNNGEIKFWQEMVAGGAAGASQVVFTNPLEIVKIRLQIQGEQLKNLSPGEAAPRRSAVWIVKHLGIVGLYKGVSACLLRDVPFSAIYFPAYAHLKKDLFKEGPDHKLKITELLMAGAIAGMPAAYFTTPADVIKTRLQVEARKGQTTYNGIFDAARKIFHEEGFKAFFKGGPARIFRSSPQFGVTLTVYELLHQFVPLPGHGTAANTTTTTTTAVANPTKLLEQQITLRSTNALKMLLDLDYRFGVYSPTKKNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MYJ8</accession>
    <name>A0A1C7MYJ8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">AP-1 complex subunit beta</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">ap1b1</name>
        <name evidence="7" type="ORF">A0J61_11757</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the adaptor complexes large subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01002434">
        <property type="protein sequence ID" value="OBZ80194.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MYJ8"/>
    <dbReference type="STRING" id="101091.A0A1C7MYJ8"/>
    <dbReference type="InParanoid" id="A0A1C7MYJ8"/>
    <dbReference type="OrthoDB" id="10254310at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030117">
        <property type="term" value="C:membrane coat"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016192">
        <property type="term" value="P:vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026739">
        <property type="entry name" value="AP_beta"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002553">
        <property type="entry name" value="Clathrin/coatomer_adapt-like_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11134">
        <property type="entry name" value="ADAPTOR COMPLEX SUBUNIT BETA FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01602">
        <property type="entry name" value="Adaptin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0653">Protein transport</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Clathrin/coatomer adaptor adaptin-like N-terminal" evidence="6">
        <location>
            <begin position="1"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="283"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004308"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01602"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OBZ80194.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="283" mass="31775" checksum="A80AAE7072C46C1E" modified="2016-11-30" version="1" fragment="single">DENPYVRKTAAVCVAKLYDLNSELAVEQDFVNSVKDMVSDVNPMVVANAVIALTDINETCPQHNVFEINSNIANKLLHALNECTEWGQIAILTAIAEYKVSDSKEAESICDRVIPRLQHANGAVVLSAIKVLMINMKHVREEALIKSMCRKMAPPLVTLLSSPPEVQYIALRNISLILQKRPEVLSNEIRVFFCKYNDPPYVKLEKLEIMIKLCNDRNVDQLLSELREYANEVDVDFVRKSVHAIGRCAIKIDEAAERCINVLLDLINTGVSYVVQEAIVVIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N019</accession>
    <name>A0A1C7N019_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Transcription factor vib-1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">vib-1_0</name>
        <name evidence="5" type="ORF">A0J61_09558</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000878">
        <property type="protein sequence ID" value="OBZ82392.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N019"/>
    <dbReference type="STRING" id="101091.A0A1C7N019"/>
    <dbReference type="InParanoid" id="A0A1C7N019"/>
    <dbReference type="OrthoDB" id="2288358at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000228">
        <property type="term" value="C:nuclear chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051321">
        <property type="term" value="P:meiotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1390">
        <property type="entry name" value="NDT80 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052605">
        <property type="entry name" value="Fungal_trans_regulator"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024061">
        <property type="entry name" value="NDT80_DNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037141">
        <property type="entry name" value="NDT80_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008967">
        <property type="entry name" value="p53-like_TF_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35144">
        <property type="entry name" value="MEIOSIS-SPECIFIC TRANSCRIPTION FACTOR NDT80"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35144:SF2">
        <property type="entry name" value="MEIOSIS-SPECIFIC TRANSCRIPTION FACTOR NDT80"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05224">
        <property type="entry name" value="NDT80_PhoG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49417">
        <property type="entry name" value="p53-like transcription factors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51517">
        <property type="entry name" value="NDT80"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NDT80" evidence="4">
        <location>
            <begin position="85"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="NDT80" evidence="2">
        <location>
            <begin position="85"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="316"/>
            <end position="578"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="40"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="91"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="349"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="360"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="371"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="393"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="457"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="476"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="499"/>
            <end position="518"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="519"/>
            <end position="533"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="534"/>
            <end position="545"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OBZ82392.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="578" mass="63723" checksum="48231567CB63FE4B" modified="2016-11-30" version="1">MQQDNKWTSPPDTPRNFMSLQSGYTYGSNEYPSSNNSTVLPGLSSQPPMPGMMSSSQPGTPRPDIISPPPDKIATTPDLIRRRPPLPSRPASFTTTTFHSNPYPTNVSLRRRRTESSMFSFETGPSFSSTKQMLDLWNMDQSNSYQVNVNAKMDRGFFRADQDWTCYRRNYFQVSATFDVTGMNYALQGPEVPCLVGTENQEIHQVDFFSIGVSARVAGSDKKIELVQHTPKRDKGPQMVPEPRVVNAGGNLHLASVGSNHNIVTFERMQFKTATANNGKRRAAQQYYEIVIDLCANTPTGKQFKVATINSAPLVVRGRSPGHYADSHTRYRSMDAGQPSSAPFGMMGGPNPTSSTSTPNVPPPPPPPPSSSAAAAVPSGPSAGVNQDDHYMQSPQSARFNVNPPSGNHDFGNPYSSYPPPPPPSQQTSGYAPYSVGGYGPVMNNPHVNRNDEDGSQRQGGNPNSNNYMMHPYAAHSLSHSSQPQQHPHPPSSQHNSQGDSYYNSTNNDMYNNQQDNKYWSREHMQPHPDQHNRYNGSNNTNNNNYEFGYSMRPHPTNSNAPPPNTTMDPNPLDAGRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-06-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N0C0</accession>
    <name>A0A1C7N0C0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_09423</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000847">
        <property type="protein sequence ID" value="OBZ82523.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N0C0"/>
    <dbReference type="InParanoid" id="A0A1C7N0C0"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="75"/>
            <end position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ82523.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="222" mass="25299" checksum="D0831A7B26EFFB7B" modified="2016-11-30" version="1">MPNTVSEKEEQIAPLTKNNQLVSQSHRLAADQQIPMSTASSISAAPTMDYLASSRSLIQNKQPTMSRFLMSKHRTMPSTNQKEPVDSAPQHSKPMISPSIIRSEASTLPKIAPTRDKIIPQKRQLNEIFQQTTSQAPLHQQVKVIQSPNLDELQMHYPQYKARLNLNYRIGIEDYLKHPKTDTKNIEVRSDLCLKQQDEVEAYAAKDIRLQVVEIGLFKRKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N0I7</accession>
    <name>A0A1C7N0I7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Helitron helicase-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_09775</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000934">
        <property type="protein sequence ID" value="OBZ82176.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N0I7"/>
    <dbReference type="STRING" id="101091.A0A1C7N0I7"/>
    <dbReference type="InParanoid" id="A0A1C7N0I7"/>
    <dbReference type="OrthoDB" id="2278933at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45786:SF74">
        <property type="entry name" value="ATP-DEPENDENT DNA HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45786">
        <property type="entry name" value="DNA BINDING PROTEIN-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ82176.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="184" mass="20775" checksum="6AB0CB5A563BA3F0" modified="2016-11-30" version="1">MNAAANSELNSSTMLALLEMMHEINPFVEYFKTMADMDVGNRQSSSDTISRDIRMIFRAENTPDSRRYNAPTAAEIGVLIVGGDGDRRPETEPTNRDIAVRLKGDDNILSHIKETNQFYDLLQYVLMFPQGTPGRCCGTLPVAPNINDIRINNADTTPYFQAVLRNPIKKITMMDFYSSMLMIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N0L3</accession>
    <name>A0A1C7N0L3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="17">Phospholipid-transporting ATPase</fullName>
            <ecNumber evidence="17">7.6.2.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="22" type="primary">ATP9B</name>
        <name evidence="22" type="ORF">A0J61_09779</name>
    </gene>
    <organism evidence="22 23">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="22 23" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="22 23">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12 17">
            <text>ATP + H2O + phospholipidSide 1 = ADP + phosphate + phospholipidSide 2.</text>
            <dbReference type="EC" id="7.6.2.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>a 1,2-diacyl-sn-glycero-3-phosphoethanolamine(out) + ATP + H2O = a 1,2-diacyl-sn-glycero-3-phosphoethanolamine(in) + ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:66132"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:64612"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="13">
            <dbReference type="Rhea" id="RHEA:66133"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="16">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Endomembrane system</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1 17">Membrane</location>
            <topology evidence="1 17">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 17">Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="22">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="7.6.2.1" evidence="17"/>
    <dbReference type="EMBL" id="LUGH01000935">
        <property type="protein sequence ID" value="OBZ82169.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N0L3"/>
    <dbReference type="FunCoup" id="A0A1C7N0L3">
        <property type="interactions" value="232"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N0L3"/>
    <dbReference type="InParanoid" id="A0A1C7N0L3"/>
    <dbReference type="OrthoDB" id="377733at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005768">
        <property type="term" value="C:endosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005802">
        <property type="term" value="C:trans-Golgi network"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140326">
        <property type="term" value="F:ATPase-coupled intramembrane lipid transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006897">
        <property type="term" value="P:endocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045332">
        <property type="term" value="P:phospholipid translocation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006890">
        <property type="term" value="P:retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.1110.10:FF:000097">
        <property type="entry name" value="Phospholipid-transporting ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.150.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023299">
        <property type="entry name" value="ATPase_P-typ_cyto_dom_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018303">
        <property type="entry name" value="ATPase_P-typ_P_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023298">
        <property type="entry name" value="ATPase_P-typ_TM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008250">
        <property type="entry name" value="ATPase_P-typ_transduc_dom_A_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059000">
        <property type="entry name" value="ATPase_P-type_domA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006539">
        <property type="entry name" value="P-type_ATPase_IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032631">
        <property type="entry name" value="P-type_ATPase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001757">
        <property type="entry name" value="P_typ_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032630">
        <property type="entry name" value="P_typ_ATPase_c"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044492">
        <property type="entry name" value="P_typ_ATPase_HD_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01652">
        <property type="entry name" value="ATPase-Plipid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01494">
        <property type="entry name" value="ATPase_P-type"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24092:SF5">
        <property type="entry name" value="PHOSPHOLIPID-TRANSPORTING ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24092">
        <property type="entry name" value="PROBABLE PHOSPHOLIPID-TRANSPORTING ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13246">
        <property type="entry name" value="Cation_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00122">
        <property type="entry name" value="E1-E2_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16212">
        <property type="entry name" value="PhoLip_ATPase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16209">
        <property type="entry name" value="PhoLip_ATPase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00119">
        <property type="entry name" value="CATATPASE"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG00002">
        <property type="entry name" value="C1.7:_P-type_atpase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00003">
        <property type="entry name" value="Haloacid_Dehalogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00027">
        <property type="entry name" value="p-type_atpase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81653">
        <property type="entry name" value="Calcium ATPase, transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81665">
        <property type="entry name" value="Calcium ATPase, transmembrane domain M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81660">
        <property type="entry name" value="Metal cation-transporting ATPase, ATP-binding domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00154">
        <property type="entry name" value="ATPASE_E1_E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 15 17" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8 16 17" id="KW-0460">Magnesium</keyword>
    <keyword evidence="11 17" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 16" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 15 17" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="23" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9 17" id="KW-1278">Translocase</keyword>
    <keyword evidence="4 17" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10 17" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="117"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="151"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="357"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="382"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="860"/>
            <end position="880"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="886"/>
            <end position="908"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="938"/>
            <end position="958"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="964"/>
            <end position="981"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="993"/>
            <end position="1014"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="1026"/>
            <end position="1044"/>
        </location>
    </feature>
    <feature type="domain" description="P-type ATPase N-terminal" evidence="20">
        <location>
            <begin position="98"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="domain" description="P-type ATPase A" evidence="19">
        <location>
            <begin position="197"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="domain" description="P-type ATPase C-terminal" evidence="21">
        <location>
            <begin position="826"/>
            <end position="1053"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="18">
        <location>
            <begin position="46"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="18">
        <location>
            <begin position="46"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="active site" description="4-aspartylphosphate intermediate" evidence="14">
        <location>
            <position position="445"/>
        </location>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="445"/>
        </location>
        <ligand>
            <name>ATP</name>
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        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="445"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
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    </feature>
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        <ligand>
            <name>ATP</name>
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            <name>ATP</name>
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        </ligand>
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            <name>ATP</name>
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        </ligand>
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        </ligand>
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        <location>
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        <location>
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            <dbReference type="ChEBI" id="CHEBI:18420"/>
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    </evidence>
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        <source>
            <dbReference type="RuleBase" id="RU362033"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
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            <dbReference type="Pfam" id="PF00122"/>
        </source>
    </evidence>
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            <dbReference type="Pfam" id="PF16209"/>
        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="1060" mass="120252" checksum="3D3C4427EC110107" modified="2016-11-30" version="1">MFRDSRPIALRKLNLFSNRKHRTSDSIHSDEDPLLDEEAALHPALSPISSRHSSTSNSIRRSSVKPERKKQKGKDSFIVRLFSKKKVCSPRTIRLQANDKEKRKFAANVIINQKYNFFTFFPIVLFEQFVIFFNLYFLLVALSQFVPALKIGYILTYFGPLCFVLLITISKEALDDYQRYKRDKEANSQLYQCLTPNGFQHIPSSKIRVGDMIHITKDQRIPADMILLRTTEESGASFIRTDQLDGETDWKLRLAIPSLQRLSSDQDLLNIHGHIYADAPHKDIHSFVGNISVNDPQTDIDQIEPLGVENTMWTNTVLASGSVIGFVIYTGKDTRAVMNTNHPKTKVGLLDKEINQLAKILFIVTLLLSVVMVGLNGFRGVWYIYVFRFLILFSSIIPIGLRVNLDMGKTVYSRQIESDEDIMGTIVRTSTLPEELGRVEYLLTDKTGTLTQNDMELKKLHMGTMSYSLDTMDEIQTHVAAAFETSQQHSDGMKGRRNISVRIRDIVQALALCHNVTPSVNSDGTITYQASSPDEVAIVKWTEHMGLSLVGRDVNTIQLRVDATGDILYYDVLNIFPFSSETKRMGIIVRNRQTQEVNFYEKGADTVMARIVQYNDWLNEECDNMAREGLRTLVVAKKSLSEDAYKEFTDRYHDAEVSLHDRNMLKQSVIESLLESNLELLGLTGVEDKLQEGVKNTLEQMRNAGLKVWMLTGIHTVAKLKTAMDAADEIDNLRTKTDNCLVIDGESLQLCLDHFIDEFIEIVTLMPVVVCCRCSPTQKADITRLIKDYTNKRVLCIGDGGNDVSMIQAADVGVGIVGKEGKQASLAADFSITQFSHLTRLLLWHGRNSYKRSAKLSQFVIHRGLIISIMQAVFSALFYFAPIALFQGMLIVGYATIYTNAPVFSLVLDQDVSEEIAMMYPELYKDLTKGRSLSYRTFFTWLLISVYQGGAIMILSILLFEDEFIHIVSISFTALIFNELLMVALEINTWHRIMFLAELITVLIYFGSMWLLPTYFDMSFILTSRFVWKVAVITAVSSCPLYIVKVIKRRIAPPSYTKLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N0M7</accession>
    <name>A0A1C7N0M7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Mannan polymerase II complex anp1 subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">anp1_2</name>
        <name evidence="2" type="ORF">A0J61_09323</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ANP1/MMN9/VAN1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000825">
        <property type="protein sequence ID" value="OBZ82623.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N0M7"/>
    <dbReference type="FunCoup" id="A0A1C7N0M7">
        <property type="interactions" value="19"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N0M7"/>
    <dbReference type="InParanoid" id="A0A1C7N0M7"/>
    <dbReference type="OrthoDB" id="2405412at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000136">
        <property type="term" value="C:mannan polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000009">
        <property type="term" value="F:alpha-1,6-mannosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000032">
        <property type="term" value="P:cell wall mannoprotein biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006487">
        <property type="term" value="P:protein N-linked glycosylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="entry name" value="Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052086">
        <property type="entry name" value="Mannan_Polymerase_Subunit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43083:SF6">
        <property type="entry name" value="MANNAN POLYMERASE COMPLEXES SUBUNIT MNN9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43083">
        <property type="entry name" value="MANNAN POLYMERASE II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03452">
        <property type="entry name" value="Anp1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00037964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ82623.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="296" mass="33938" checksum="EE7E05F50EFA5D55" modified="2016-11-30" version="1">MALTSADQRPLMSNRKPKYINLNKRPTEDQKVLILTPLKNAAPYLARYFQILQTLDYPKQLISLAFLVSDTTDRTLDELRTVADSLSDQYDSMDIFVKDFDFKLSEGNRHGYDVQPQRRAWMARSRNYLLTTALREEHDWVLWLDVDIVQFPKSILKDLQKLDVDVVVPNCLKETEDGSFWGYDQNNWQETEESIALQESLDPDVVLLQGYEQLETKRLAMVDMPTHGNPLDKVPLDGVGATFTLVKANVHREGVIFPPFPYKHQVETEGFAKMAKTMGFGVYGLPAYLIYHASNG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N155</accession>
    <name>A0A1C7N155_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">K Homology domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">A0J61_09148</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000784">
        <property type="protein sequence ID" value="OBZ82802.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N155"/>
    <dbReference type="STRING" id="101091.A0A1C7N155"/>
    <dbReference type="InParanoid" id="A0A1C7N155"/>
    <dbReference type="OrthoDB" id="271862at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd22453">
        <property type="entry name" value="KH-I_MUG60_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1370.10">
        <property type="entry name" value="K Homology domain, type 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004087">
        <property type="entry name" value="KH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004088">
        <property type="entry name" value="KH_dom_type_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036612">
        <property type="entry name" value="KH_dom_type_1_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056553">
        <property type="entry name" value="KH_Mug60-KHD4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00013">
        <property type="entry name" value="KH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24563">
        <property type="entry name" value="KH_Mug60-KHD4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00322">
        <property type="entry name" value="KH"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54791">
        <property type="entry name" value="Eukaryotic type KH-domain (KH-domain type I)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50084">
        <property type="entry name" value="KH_TYPE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="K Homology" evidence="3">
        <location>
            <begin position="70"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="domain" description="K Homology" evidence="3">
        <location>
            <begin position="359"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="750"/>
            <end position="770"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00322"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OBZ82802.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="868" mass="98781" checksum="2F42C501D8E34327" modified="2016-11-30" version="1">MVTIDSPSMNALFHPEIKARLSKIAKRHDIQIKVVSSSSSEPEIQLIGSIDDIEVARVEVLCQMDLLCDMHMETIETIPSFLHNIIAGRRHTQLHSIMEETSTNVYLQSPFSHVCKERKQDSNLICLTGQSKSELLKAKELLTKLSSQKLKSFYQKDLTMAANKIDWLLLFKRSQLRKIMMDNGSFFSFPILGATSNTVSVYAENRVNVERSIRLLNQLITVLYDASFELSPRSLKDVNMSLCLGKLSKSTGVTASYFDDNHVISLFGTEKQVKHTYQLLAKIPFFKESQKFTSFRLELATDQLEFISGKKNGKINKIMKACVVNIRFVAVNEYNSSIFIESTHYKSAFEGLLLLQDELPAEVSFYVPEIYHRRIIGVGGKNIQKVMKKYGVYVKFSGAEELASLGGYFENEDNVVARTPMKNQVNLENLKQTVTDFVGFEKDRDYVSQPFTIPFTLQRTLLEHHDSELHEVCHSHNVKIRWPERLGTSHAEIYGPQSHISAVSLFLSSIVKVEQHLVIAYAEEFGKTVSEDLVTQLRKDLSGLEDSVYLIDVLVLQQKQYQFHSKQLEFSWISHAGEKYVVFRMLGSLASKQHFEKTKSIIQSRLEAHNLPFTELKSNSTLLESDQGSNEGTYKSMFNNTEVPKKETQVSSNLKQLPRSQSCYEPALHPLEMPRTKSFCTTTNSFLSMPVHNHRNIWASAQASVKHNSLPMLPIDSIPLSQFNMHSAFPVQPHHPFSPMADEAMTENGYHPQSRAKSSVPTIGTRHQDPFPEQYLSHQQYPQRHSSWPNIFLGGRDLFDTLPSRRASSINTTQYAFEHQPNSCSFLQHHKKAHGLSPSSSPMHIDTMMLPAINSFEHRYQDPSGFNI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N1Q4</accession>
    <name>A0A1C7N1Q4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Calcium-transporting ATPase 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">cta3_1</name>
        <name evidence="13" type="ORF">A0J61_09391</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000839">
        <property type="protein sequence ID" value="OBZ82559.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N1Q4"/>
    <dbReference type="STRING" id="101091.A0A1C7N1Q4"/>
    <dbReference type="InParanoid" id="A0A1C7N1Q4"/>
    <dbReference type="OrthoDB" id="116380at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030001">
        <property type="term" value="P:metal ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1000:FF:000028">
        <property type="entry name" value="Calcium-transporting P-type ATPase, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.70.150.10:FF:000160">
        <property type="entry name" value="Sarcoplasmic/endoplasmic reticulum calcium ATPase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.150.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, transmembrane domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006068">
        <property type="entry name" value="ATPase_P-typ_cation-transptr_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004014">
        <property type="entry name" value="ATPase_P-typ_cation-transptr_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023299">
        <property type="entry name" value="ATPase_P-typ_cyto_dom_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018303">
        <property type="entry name" value="ATPase_P-typ_P_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023298">
        <property type="entry name" value="ATPase_P-typ_TM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008250">
        <property type="entry name" value="ATPase_P-typ_transduc_dom_A_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059000">
        <property type="entry name" value="ATPase_P-type_domA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001757">
        <property type="entry name" value="P_typ_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044492">
        <property type="entry name" value="P_typ_ATPase_HD_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01494">
        <property type="entry name" value="ATPase_P-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42861">
        <property type="entry name" value="CALCIUM-TRANSPORTING ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13246">
        <property type="entry name" value="Cation_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00689">
        <property type="entry name" value="Cation_ATPase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00690">
        <property type="entry name" value="Cation_ATPase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00122">
        <property type="entry name" value="E1-E2_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00119">
        <property type="entry name" value="CATATPASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00120">
        <property type="entry name" value="HATPASE"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG00002">
        <property type="entry name" value="C1.7:_P-type_atpase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00003">
        <property type="entry name" value="Haloacid_Dehalogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00027">
        <property type="entry name" value="p-type_atpase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00831">
        <property type="entry name" value="Cation_ATPase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81653">
        <property type="entry name" value="Calcium ATPase, transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81665">
        <property type="entry name" value="Calcium ATPase, transmembrane domain M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81660">
        <property type="entry name" value="Metal cation-transporting ATPase, ATP-binding domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00154">
        <property type="entry name" value="ATPASE_E1_E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="9 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-1278">Translocase</keyword>
    <keyword evidence="3 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="61"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="87"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="258"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="285"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="747"/>
            <end position="768"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="780"/>
            <end position="798"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="828"/>
            <end position="850"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="870"/>
            <end position="892"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="913"/>
            <end position="931"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="943"/>
            <end position="965"/>
        </location>
    </feature>
    <feature type="domain" description="Cation-transporting P-type ATPase N-terminal" evidence="12">
        <location>
            <begin position="12"/>
            <end position="86"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00038148"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM00831"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="OBZ82559.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="988" mass="109288" checksum="7EA5AE36D2A5568E" modified="2016-11-30" version="1">MKDTTESIEVSDWHSKTIEETAELLHTSLTTGLNSNDIPSRHNKYGYNELSADGGPKWLKVLMGQLVDVMNWIFVALAVASYCLKDYITGSLLLFIALLNIYLGFSQEYAAEQTLAALRSLSSPMATVIRNDAEQSIPSREIVPGDILLVKEGDSVGADARLIYVSNLEADEALLTGESMPVTKQLTVLANPGKLLLKNEPLGDRVNMLYSSTVISKGRGKAIVTATGMRTEIGRVASKLNESNDSDRTRLQKSLDKMYFILLVTSVICVIIVLASVKFKADYDIGMYSMTAALSVLPAGLTTVMTVTLVLGGKEMTKQRAIVRKLKCLETLGSVTNIFSDKTGTLTMARMVVVRFWTPLEGFFYVTSNGLQPTGDIYHTQEEIQEKFTDDMSSHLVDKSNLSPEIVNLVRCAALCNMSSIYPRSKHNTDNEKNDLEAVDETESDDWISSGAPTEVALQVFAHKFGMGKSDLTTNGWEILMEYQFDSTIKRMTTIWQDTNSGDIYAFTKGAAERVIELCSNATYESDRLPILDKVEKLAAKGLRVMAMSFKKLESDSRSITKLSRDQVESNLCFLGLTGIYDPPRKESRQAVQEAHQAGISVHMLTGDHEITATAIAKEIKILDMNRLSPNDLKDLVMTGSKFDAMTDEEIDALKDLPLVVARCSPETKVKMIQASSRRNNIAAMTGDGVNDSPSLRIADVGIAMGKNGSDVAKQASDIILTDDNFATIIRAIAEGRRIYQNMQRFLLYYWILLFSMAFVVLLCLAIRDPIGRSAAPMSTLQMIFVYIAITPPAGALSTQPPSLTVMKEPPRPPTESIFNREIVMDTLFYSITITILTLVAYVVPLYTIGNGIGGVNCDSNYISGSCDSFFRGRTSLLVTFVLCSLVVMVHCRSYRQCEWNLKGIQKTLHSRTFVGTLVFDLVGLCIFMYIPDVAILGFRMLGINWEWGLDVGLVLFFIVVGEVYKATKRCLMKPMDSGKTNLDEENR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N1W8</accession>
    <name>A0A1C7N1W8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Myb-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_10597</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001259">
        <property type="protein sequence ID" value="OBZ81354.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N1W8"/>
    <dbReference type="STRING" id="101091.A0A1C7N1W8"/>
    <dbReference type="InParanoid" id="A0A1C7N1W8"/>
    <dbReference type="OrthoDB" id="6781668at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00167">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001005">
        <property type="entry name" value="SANT/Myb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="SMART" id="SM00717">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50090">
        <property type="entry name" value="MYB_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Myb-like" evidence="2">
        <location>
            <begin position="188"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="283"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="303"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="326"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="336"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="394"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="444"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="456"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ81354.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="544" mass="62456" checksum="9E51B2EC1C129936" modified="2016-11-30" version="1" fragment="single">RKKNFFNEEVTEEEREIIAQRVALQQRQFAAYEVREKARKSNRIRTVFDYVTDEEITELLNDSNQDEDEVIYNLTKPGYLSGIRKTIALKYADEESNYAPVMSNEQRTAYQQLLKKRKETLKKTINADAKKRYRTYERLGLDEALEKLNNNEVDPEKAFEGWSEARVKAYQMIEQNPNSYYYRFNAPGEIQRRGQWSEDEKELFHKRLAEVGANGQWGIFSMKIPGRVGYQCSNYYRLLIETHKISDPNYVLDEKGKAHFLFDKKSSDGQVKKTFRTHTKLASVKKKKEAVDTDTVSDDSTPEQENITEPSSSKTVPVDLKRRKSSPSVTTNEVATSSKTSRSTSRANSKTTANSSITKGNSTTNTYSTPTPAAPKPVSGVRRRRRVVRSKDDDTSDDYDDDYSGSFTTRAKTVADEKRRSKRQRRPTANAIESGLASQLLAMQREDESMRNDSGDNSDEDDESCDPTCPLPGFIDPITLEQIIKPAISKYGHVMGYDSWIRCLNNWEGQRNICPLTKKPLTKRDLVVLTFENIEEYRNQIVNI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N1Z0</accession>
    <name>A0A1C7N1Z0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_09253</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000808">
        <property type="protein sequence ID" value="OBZ82696.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N1Z0"/>
    <dbReference type="InParanoid" id="A0A1C7N1Z0"/>
    <dbReference type="OrthoDB" id="2382382at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ82696.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="113" mass="13126" checksum="8057DB5A7FB12DCD" modified="2016-11-30" version="1">MPTFDTFCHSPRSIWYKILQLLQSDQQFSTPTDEIKPSSLGRAKYKRRRSAVDCPQAIPNAMVIPPFSPTYCKPNEFPYSNFYVKLPNGNWMVRYRSGNRKILGTDELEGYLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N2K5</accession>
    <name>A0A1C7N2K5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">ATP synthase subunit delta, mitochondrial</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13">F-ATPase delta subunit</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="15" type="primary">atpD</name>
        <name evidence="15" type="ORF">A0J61_08737</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ATPase epsilon chain family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000701">
        <property type="protein sequence ID" value="OBZ83218.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N2K5"/>
    <dbReference type="FunCoup" id="A0A1C7N2K5">
        <property type="interactions" value="306"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N2K5"/>
    <dbReference type="InParanoid" id="A0A1C7N2K5"/>
    <dbReference type="OrthoDB" id="270171at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045259">
        <property type="term" value="C:proton-transporting ATP synthase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046933">
        <property type="term" value="F:proton-transporting ATP synthase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd12152">
        <property type="entry name" value="F1-ATPase_delta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.15.10:FF:000003">
        <property type="entry name" value="ATP synthase subunit delta, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.15.10">
        <property type="entry name" value="F0F1 ATP synthase delta/epsilon subunit, N-terminal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00530">
        <property type="entry name" value="ATP_synth_epsil_bac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001469">
        <property type="entry name" value="ATP_synth_F1_dsu/esu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020546">
        <property type="entry name" value="ATP_synth_F1_dsu/esu_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036771">
        <property type="entry name" value="ATPsynth_dsu/esu_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13822">
        <property type="entry name" value="ATP SYNTHASE DELTA/EPSILON CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13822:SF7">
        <property type="entry name" value="ATP SYNTHASE SUBUNIT DELTA, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02823">
        <property type="entry name" value="ATP-synt_DE_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51344">
        <property type="entry name" value="Epsilon subunit of F1F0-ATP synthase N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-0066">ATP synthesis</keyword>
    <keyword evidence="11" id="KW-0139">CF(1)</keyword>
    <keyword evidence="5" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="8" id="KW-0406">Ion transport</keyword>
    <keyword evidence="10" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ATP synthase F1 complex delta/epsilon subunit N-terminal" evidence="14">
        <location>
            <begin position="30"/>
            <end position="102"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005712"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00016960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023196"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023310"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00031669"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF02823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="OBZ83218.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="161" mass="17058" checksum="158268C0AE207D32" modified="2016-11-30" version="1">MNVLARSARAAIKPMARFYATEAAAASDALRLTLVVPHKAIYKATNVQQVNLAATSGDMGILANHVPSIEQLNPGVVEVIESGEITKKFFVSGGFATINPDSSLNINAVEAFPLEELSLERVQAGLAEAQRQAGSAASEQEKAAAKIEVEVYEALQHALTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N2L2</accession>
    <name>A0A1C7N2L2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Succinate-CoA ligase subunit beta</fullName>
            <ecNumber evidence="12">6.2.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="primary">B9J10.140</name>
        <name evidence="15" type="ORF">A0J61_08697</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Carbohydrate metabolism; tricarboxylic acid cycle; succinate from succinyl-CoA (ligase route): step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="11">Heterodimer of an alpha and a beta subunit. The beta subunit determines specificity for GTP.</text>
    </comment>
    <comment type="similarity">
        <text evidence="12">Belongs to the succinate/malate CoA ligase beta subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.2.1.-" evidence="12"/>
    <dbReference type="EMBL" id="LUGH01000695">
        <property type="protein sequence ID" value="OBZ83251.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N2L2"/>
    <dbReference type="FunCoup" id="A0A1C7N2L2">
        <property type="interactions" value="427"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N2L2"/>
    <dbReference type="InParanoid" id="A0A1C7N2L2"/>
    <dbReference type="OrthoDB" id="1552at2759"/>
    <dbReference type="UniPathway" id="UPA00223">
        <property type="reaction ID" value="UER00999"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042709">
        <property type="term" value="C:succinate-CoA ligase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004775">
        <property type="term" value="F:succinate-CoA ligase (ADP-forming) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006104">
        <property type="term" value="P:succinyl-CoA metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.470.20:FF:000002">
        <property type="entry name" value="Succinate--CoA ligase [ADP-forming] subunit beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.261:FF:000001">
        <property type="entry name" value="Succinate--CoA ligase [ADP-forming] subunit beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1490.20:FF:000004">
        <property type="entry name" value="Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.20">
        <property type="entry name" value="ATP-grasp fold, A domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.470.20">
        <property type="entry name" value="ATP-grasp fold, B domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.261">
        <property type="entry name" value="Succinyl-CoA synthetase domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00558">
        <property type="entry name" value="Succ_CoA_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03220">
        <property type="entry name" value="Succ_CoA_betaA_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013650">
        <property type="entry name" value="ATP-grasp_succ-CoA_synth-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013815">
        <property type="entry name" value="ATP_grasp_subdomain_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017866">
        <property type="entry name" value="Succ-CoA_synthase_bsu_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005811">
        <property type="entry name" value="SUCC_ACL_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034723">
        <property type="entry name" value="Succ_CoA_betaA_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005809">
        <property type="entry name" value="Succ_CoA_ligase-like_bsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016102">
        <property type="entry name" value="Succinyl-CoA_synth-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF001913">
        <property type="entry name" value="PRK00696.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01016">
        <property type="entry name" value="sucCoAbeta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11815:SF1">
        <property type="entry name" value="SUCCINATE--COA LIGASE [ADP-FORMING] SUBUNIT BETA, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11815">
        <property type="entry name" value="SUCCINYL-COA SYNTHETASE BETA CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08442">
        <property type="entry name" value="ATP-grasp_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00549">
        <property type="entry name" value="Ligase_CoA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001554">
        <property type="entry name" value="SucCS_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56059">
        <property type="entry name" value="Glutathione synthetase ATP-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52210">
        <property type="entry name" value="Succinyl-CoA synthetase domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01217">
        <property type="entry name" value="SUCCINYL_COA_LIG_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 12 15" id="KW-0436">Ligase</keyword>
    <keyword evidence="8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6 12" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="3" id="KW-0816">Tricarboxylic acid cycle</keyword>
    <feature type="domain" description="ATP-grasp fold succinyl-CoA synthetase-type" evidence="14">
        <location>
            <begin position="33"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="domain" description="ATP-citrate synthase/succinyl-CoA ligase C-terminal" evidence="13">
        <location>
            <begin position="300"/>
            <end position="420"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005064"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00063570"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU361258"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF00549"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF08442"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="OBZ83251.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="439" mass="47360" checksum="993346C5F5B64F72" modified="2016-11-30" version="1">MLFNSLRTASSIAQRASLVARKPVQQQQKRFLNIHEYLSVKLLREYGINAPKGEVAKTPEEAFEIAKSLGSDDLVIKAQVLAGGRGKGTFDNGYKGGVKTFGTPEEARELAEKMLGHKLITKQTGAEGKPCNAVYICERKYARNEYYFAILLDRKSAGPVIVASSQGGVDIEGVAAANPDAIITMPVDLKQGLSKDQALDLAKRLGFTPKGQEQAADTFLGLYKLFTEKDATQVEINPLSESSDNQVLCMDAKLNFDDNADFKQKEVFALRDFTQEDSREIAAAKHNLNYIGLDGSIGCLVNGAGLAMATMDIIQLHGGKPANFLDVGGAATPDAVKAAFEIITSDPQVSSAFVNIFGGIMRCDVIAEGIIAAAKDLDLKIPLIVRLRGTKVDEAKKLIAESGLRIFAIEDLDTAAQKAVKFSQIVTLARDANIDLKFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N3I3</accession>
    <name>A0A1C7N3I3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Epsin-1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">Epn1</name>
        <name evidence="8" type="ORF">A0J61_08354</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the epsin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000634">
        <property type="protein sequence ID" value="OBZ83597.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N3I3"/>
    <dbReference type="STRING" id="101091.A0A1C7N3I3"/>
    <dbReference type="InParanoid" id="A0A1C7N3I3"/>
    <dbReference type="OrthoDB" id="4033880at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030125">
        <property type="term" value="C:clathrin vesicle coat"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005768">
        <property type="term" value="C:endosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030276">
        <property type="term" value="F:clathrin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005543">
        <property type="term" value="F:phospholipid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007015">
        <property type="term" value="P:actin filament organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006897">
        <property type="term" value="P:endocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd16991">
        <property type="entry name" value="ENTH_Ent1_Ent2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.90:FF:000006">
        <property type="entry name" value="Clathrin interactor 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013809">
        <property type="entry name" value="ENTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008942">
        <property type="entry name" value="ENTH_VHS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003903">
        <property type="entry name" value="UIM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12276:SF110">
        <property type="entry name" value="EPSIN-1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12276">
        <property type="entry name" value="EPSIN/ENT-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01417">
        <property type="entry name" value="ENTH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00273">
        <property type="entry name" value="ENTH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00726">
        <property type="entry name" value="UIM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48464">
        <property type="entry name" value="ENTH/VHS domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50942">
        <property type="entry name" value="ENTH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0446">Lipid-binding</keyword>
    <keyword evidence="4" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ENTH" evidence="7">
        <location>
            <begin position="28"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="206"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="281"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="344"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="512"/>
            <end position="591"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="206"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="281"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="352"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="512"/>
            <end position="548"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="558"/>
            <end position="578"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="582"/>
            <end position="591"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010130"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OBZ83597.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="591" mass="66488" checksum="F1954773FC6F9C29" modified="2016-11-30" version="1">MKAREREKSEEAQKVEECRYSLLLSSKNIAKGFSDVQIKVREATSNDPWGPSGTLMNEIAQLTYNETDFIEIMDMIDRRLNDKGKNWRHVFKALLLLDYCLHVGSENVVLYAKENIYVVKTLKEFQHVEENGKDVGANVRQKAKDITNLLTDDNRLREERRMRQGMRDRMANVGDYLNETVRYYNGLNGGEGQQWDDENELKKALAESKRVADEEEKNRRQGDDDLEKAIQLSQQEAMEKEKKERERLERENAANLFGSSNDPFQPFPQQAMPTGFNAYQQFQQQPQQQQIEWNPFQQQQQQQQQNPYATGLQAQMTGFVPQQQSSMDLFSQQNIQPQVTGFVPQQTGSTNPFSQSQPSSVLQPQQTKPYDYSGLMFGNASQQPAATSAASPAFATNAPDFFGTKTSTSSMTPTASSGFASNAPDFFNTSSTTNTFTPNTASAIPPSTNAFATSHATNSFSPQTAPALPPKEQDLKYSKLNSLLANKEDGMDTFGNQGNLRIPYGTGFASSFKSSNPVEQSSTSTNSPFLTNKNPFGQMPTNTSSPAPQKSLLDLMQEQKQQQQQQQQQQQQFFPQQPMMTGFNNTNNSLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N3V9</accession>
    <name>A0A1C7N3V9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">ENTH domain-containing protein C19F8.03c</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_08119</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000597">
        <property type="protein sequence ID" value="OBZ83835.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N3V9"/>
    <dbReference type="STRING" id="101091.A0A1C7N3V9"/>
    <dbReference type="InParanoid" id="A0A1C7N3V9"/>
    <dbReference type="OrthoDB" id="44015at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005905">
        <property type="term" value="C:clathrin-coated pit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030136">
        <property type="term" value="C:clathrin-coated vesicle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005545">
        <property type="term" value="F:1-phosphatidylinositol binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032050">
        <property type="term" value="F:clathrin heavy chain binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005546">
        <property type="term" value="F:phosphatidylinositol-4,5-bisphosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000149">
        <property type="term" value="F:SNARE binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048268">
        <property type="term" value="P:clathrin coat assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072583">
        <property type="term" value="P:clathrin-dependent endocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006900">
        <property type="term" value="P:vesicle budding from membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd16988">
        <property type="entry name" value="ANTH_N_YAP180"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.150">
        <property type="entry name" value="ANTH domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011417">
        <property type="entry name" value="ANTH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014712">
        <property type="entry name" value="ANTH_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045192">
        <property type="entry name" value="AP180-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013809">
        <property type="entry name" value="ENTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008942">
        <property type="entry name" value="ENTH_VHS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22951">
        <property type="entry name" value="CLATHRIN ASSEMBLY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22951:SF5">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL-BINDING CLATHRIN ASSEMBLY PROTEIN LAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07651">
        <property type="entry name" value="ANTH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00273">
        <property type="entry name" value="ENTH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48464">
        <property type="entry name" value="ENTH/VHS domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89009">
        <property type="entry name" value="GAT-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50942">
        <property type="entry name" value="ENTH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ENTH" evidence="2">
        <location>
            <begin position="1"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="270"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="391"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="284"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="391"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="411"/>
            <end position="426"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ83835.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="426" mass="48966" checksum="F69A2A69ACFDC8A9" modified="2016-11-30" version="1">METAVRKATRLEYRPPKEKHLLTLRSFTLQSPHLIDSILSSLERRLKERTWLITYKVLVIVHYLMRNGNSELVAEAVLHRPGVLDASRIKNKAASPSNVQNIYLYRAYLDERLIVYRQLDRDYVRRIHDGEHRLRQLSVANGLLNETEALQRQMASALKCKFNFAEGDHSITFVAYRMVIDDLLALFQAVNESVVNILEHYFEMNKKNATISLKIYQLFAQQTELTIDYLNEAKRYQQDLQMNIPAVKHAPLSLAAALEEYLVEIDQQPPKTEVNLSQPPQQPPQQQLTQPQQPQFMQQQQQQFMQPSYVQQPLMQPFSNTPYNEPFMDTTFSSVNRRSTLPNRLSTSQFSPQNPFATLPAHSSSSLSNHNPFRSMSMIAQQPMIPVAKPTSSYNPFSSHSGALTPPLTPNQPLYQNPFLPSSSFH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N3W0</accession>
    <name>A0A1C7N3W0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_08223</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000613">
        <property type="protein sequence ID" value="OBZ83727.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N3W0"/>
    <dbReference type="STRING" id="101091.A0A1C7N3W0"/>
    <dbReference type="InParanoid" id="A0A1C7N3W0"/>
    <dbReference type="OrthoDB" id="2418056at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ83727.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="134" mass="15425" checksum="A1E6E7BCAE562AE7" modified="2016-11-30" version="1">MNFFSMCLPKKQHIYLPDEDNTIPIRNTTCFPCCTQIKEKSKRIGLVRLPKNKDIYPKTFISIEALLAEQEEELDDYYGQTDDEDAFHGPASLHSRNTQDIDSISYSYETDAQFLSDYRITSIIGKNTSNDNIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N5H3</accession>
    <name>A0A1C7N5H3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="11">ADP-ribosylation factor-like protein 8B</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">Arl8b</name>
        <name evidence="11" type="ORF">A0J61_07552</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Lysosome membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the small GTPase superfamily. Arf family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000515">
        <property type="protein sequence ID" value="OBZ84395.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N5H3"/>
    <dbReference type="STRING" id="101091.A0A1C7N5H3"/>
    <dbReference type="InParanoid" id="A0A1C7N5H3"/>
    <dbReference type="OrthoDB" id="2011769at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04159">
        <property type="entry name" value="Arl10_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000247">
        <property type="entry name" value="ADP-ribosylation factor-like GTPase 8A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044154">
        <property type="entry name" value="Arl8a/8b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006689">
        <property type="entry name" value="Small_GTPase_ARF/SAR"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45732">
        <property type="entry name" value="ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45732:SF7">
        <property type="entry name" value="ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00025">
        <property type="entry name" value="Arf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00328">
        <property type="entry name" value="SAR1GTPBP"/>
    </dbReference>
    <dbReference type="SMART" id="SM00177">
        <property type="entry name" value="ARF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00175">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00173">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00178">
        <property type="entry name" value="SAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51417">
        <property type="entry name" value="ARF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51419">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51422">
        <property type="entry name" value="SAR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="3" id="KW-0132">Cell division</keyword>
    <keyword evidence="5 9" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="7" id="KW-0458">Lysosome</keyword>
    <keyword evidence="10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="27"/>
            <end position="34"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="34"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="52"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="74"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="130"/>
            <end position="133"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004656"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023228"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR606689-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR606689-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="OBZ84395.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="185" mass="20872" checksum="68F2E072A2CE2444" modified="2016-11-30" version="1">MAGILQWLLDWLRSLFFKTEMELTLVGLQNSGKTTLVNVIASGQFIEDAIPTIGFNMRKVTKGNVTMKLWDIGGQPRFRSMWERYCRGVNAIVFVVDAADRDKLEAANTELKNLLEKPQLNNIPVLVLGNKNDLPNALTAEELIEELHLKSITNREVSCYSISAKNQVNIDVTLQWLIKKGKGQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N6H6</accession>
    <name>A0A1C7N6H6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_07304</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000486">
        <property type="protein sequence ID" value="OBZ84641.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N6H6"/>
    <dbReference type="STRING" id="101091.A0A1C7N6H6"/>
    <dbReference type="InParanoid" id="A0A1C7N6H6"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ84641.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="71" mass="8273" checksum="2CBA7DDB5484369B" modified="2016-11-30" version="1" fragment="single">METISDQEFRAKLESHFSLYRINLRSPVASHIKPGHWYRVDLLLVNELGLFRRADIEPDGQVEVTCDLYSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N6M0</accession>
    <name>A0A1C7N6M0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Kinesin-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">kif6_1</name>
        <name evidence="10" type="ORF">A0J61_07198</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="5">Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. KIN-13 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000474">
        <property type="protein sequence ID" value="OBZ84750.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N6M0"/>
    <dbReference type="STRING" id="101091.A0A1C7N6M0"/>
    <dbReference type="InParanoid" id="A0A1C7N6M0"/>
    <dbReference type="OrthoDB" id="3176171at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008017">
        <property type="term" value="F:microtubule binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003777">
        <property type="term" value="F:microtubule motor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007019">
        <property type="term" value="P:microtubule depolymerization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007018">
        <property type="term" value="P:microtubule-based movement"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01367">
        <property type="entry name" value="KISc_KIF2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.850.10:FF:000012">
        <property type="entry name" value="Kinesin-like protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.850.10">
        <property type="entry name" value="Kinesin motor domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027640">
        <property type="entry name" value="Kinesin-like_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019821">
        <property type="entry name" value="Kinesin_motor_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001752">
        <property type="entry name" value="Kinesin_motor_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036961">
        <property type="entry name" value="Kinesin_motor_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47971:SF20">
        <property type="entry name" value="KINESIN-LIKE PROTEIN KIF24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47971">
        <property type="entry name" value="KINESIN-RELATED PROTEIN 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00225">
        <property type="entry name" value="Kinesin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00380">
        <property type="entry name" value="KINESINHEAVY"/>
    </dbReference>
    <dbReference type="SMART" id="SM00129">
        <property type="entry name" value="KISc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00411">
        <property type="entry name" value="KINESIN_MOTOR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50067">
        <property type="entry name" value="KINESIN_MOTOR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 7" id="KW-0493">Microtubule</keyword>
    <keyword evidence="4 6 7" id="KW-0505">Motor protein</keyword>
    <keyword evidence="2 6 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Kinesin motor" evidence="9">
        <location>
            <begin position="27"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="349"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="442"/>
            <end position="517"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="349"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="360"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="382"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="449"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="478"/>
            <end position="517"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="117"/>
            <end position="124"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00061030"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00283"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000394"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50067"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OBZ84750.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="667" mass="75264" checksum="D2BEAB0ED5AD2EC9" modified="2016-11-30" version="1">MSPAKAQRGTGLMGTRYDLPLSDLNQKIRVCVRKRPLSKKEIEKGDRDMAPTLGTRSLQINEPKLRLDLTKYTEQHTFTFDDVFDLNCSNALVYERTALPLVNYIFKGGKATCFAYGQTGSGKTYTMLDPINGLYILAARDIFTLLRKPENQHLTAWIGLYEIYQGQLYDLLNERKKLFAREDGKNNVIISGLREYPIDNVDKLIQVFEYGSSVRSTGSTGANDSSSRSHAVLQILLKYKTNKKKIHGKMSFIDLAGSERGADRGEADTKTRMEGAEINKSLLALKECIRALDQDKRHTPFRQSKLTQVLKDSFVGNSRTCMIATISPGGTNSEHTLNTLRYADRVKELKGERDRRIQMERNTSNSSSGAPEELYQHQPQPSDEDPDEDEAFIQNDSNDDEYFSNESDILDDDTFNADQENIFDVDFPHEQDALIYSNFNSNSMNISSPKITSSPRFTHTSTLSAASSPEDSVFHGNKLQQRPNSMSPYSNVEATASSSSNRPLSLQMKRSSSTIPRSFSLYTPQRTTLDDLPHVRPLQHQPQQHSAMTIDTANLPQYLQARNAEPSMASPLSGVPSFGYEQMDEFVKFHRAEIREITDCTKKETKLVANISLDLSSNQESGQQKSVRSSSQFQKYLRDLDEVLERKLAAVEALRDRINETVCQIEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N7E9</accession>
    <name>A0A1C7N7E9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DMAP1-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_06971</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000447">
        <property type="protein sequence ID" value="OBZ84977.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N7E9"/>
    <dbReference type="STRING" id="101091.A0A1C7N7E9"/>
    <dbReference type="InParanoid" id="A0A1C7N7E9"/>
    <dbReference type="OrthoDB" id="263283at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010506">
        <property type="entry name" value="DMAP1-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06464">
        <property type="entry name" value="DMAP_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01137">
        <property type="entry name" value="DMAP_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51912">
        <property type="entry name" value="DMAP1_BIND"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DMAP1-binding" evidence="2">
        <location>
            <begin position="2"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="40"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="43"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="86"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="159"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="171"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="236"/>
            <end position="255"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ84977.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="266" mass="30229" checksum="1AC9480E6E35C213" modified="2016-11-30" version="1">MDSQDLPADILEKLRNLELELEDGDITPKGFEKKKATLLAEASQPSTPGISQPHNELVEDLGPEPSAADVVDFLDFLPSPTHSPTRTHEATHYMEENHKHIQQQQQPIRPPPPPPQQSYRPYNGMARGMPMNPPPYMGTPIPQHNRPYMVPSRTGYPSQQQQQQQQQQQQIRPSQQHMHTYYNQRPPPPSQSNMMYRPTQPASQAYPNPTPRPHSSAPLQTSPRPVYVARPGMYRPSPGQPQQYGNYQYNNSMGNVSRTHPAGYYK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N7Y6</accession>
    <name>A0A1C7N7Y6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Vacuolar protein sorting-associated protein 37A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">VPS37A</name>
        <name evidence="9" type="ORF">A0J61_06693</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endosome</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the VPS37 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000417">
        <property type="protein sequence ID" value="OBZ85255.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N7Y6"/>
    <dbReference type="InParanoid" id="A0A1C7N7Y6"/>
    <dbReference type="OrthoDB" id="10260857at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000813">
        <property type="term" value="C:ESCRT I complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006612">
        <property type="term" value="P:protein targeting to membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006623">
        <property type="term" value="P:protein targeting to vacuole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043162">
        <property type="term" value="P:ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd11685">
        <property type="entry name" value="UEV_TSG101-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.660">
        <property type="entry name" value="Helix hairpin bin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037202">
        <property type="entry name" value="ESCRT_assembly_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029012">
        <property type="entry name" value="Helix_hairpin_bin_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009851">
        <property type="entry name" value="Mod_r"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016135">
        <property type="entry name" value="UBQ-conjugating_enzyme/RWD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13678">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 37"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13678:SF2">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 37A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07200">
        <property type="entry name" value="Mod_r"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140111">
        <property type="entry name" value="Endosomal sorting complex assembly domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54495">
        <property type="entry name" value="UBC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51314">
        <property type="entry name" value="VPS37_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0967">Endosome</keyword>
    <keyword evidence="5 6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0813">Transport</keyword>
    <feature type="domain" description="VPS37 C-terminal" evidence="8">
        <location>
            <begin position="223"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="103"/>
            <end position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022753"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00646"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51314"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OBZ85255.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="312" mass="35607" checksum="6FBDB798C52D8149" modified="2016-11-30" version="1">MAQDLKRQHINTLLTQVPSTITVVDGQIYEIPLNQQNNTFLLVNLPAQFPEEPPVITVSPTGMRHPWIEGDVVMHDALPTWNQQSNLGYLLKDIRDEFIQRPPARKGLNDSSPQHTAKSEEGYGSRPPPPIPSSNLNTAPAVNLEYNAISKLSLEDVEELLQNETAFDIFFNSLDAVKNLKSFQEDLRNANEQLAHKHLSREDQVTKARSEVETLFNQFHLAKLEFDQKEKLQQEAYNRFSCATVLTRLKASVYESDELSESVAQSFLDGNLDNDSFVKQFNEFRKVYHLRASKLERAQKDKLFVAXSKNKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N8G1</accession>
    <name>A0A1C7N8G1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Transcription factor SKN7</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">SKN7_1</name>
        <name evidence="9" type="ORF">A0J61_06598</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the HSF family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000406">
        <property type="protein sequence ID" value="OBZ85347.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N8G1"/>
    <dbReference type="STRING" id="101091.A0A1C7N8G1"/>
    <dbReference type="InParanoid" id="A0A1C7N8G1"/>
    <dbReference type="OrthoDB" id="60033at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.10:FF:000027">
        <property type="entry name" value="Heat shock transcription factor 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000232">
        <property type="entry name" value="HSF_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10015:SF427">
        <property type="entry name" value="HEAT SHOCK FACTOR PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10015">
        <property type="entry name" value="HEAT SHOCK TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00447">
        <property type="entry name" value="HSF_DNA-bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00056">
        <property type="entry name" value="HSFDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00415">
        <property type="entry name" value="HSF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00434">
        <property type="entry name" value="HSF_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HSF-type DNA-binding" evidence="8">
        <location>
            <begin position="74"/>
            <end position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006403"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU004020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OBZ85347.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="329" mass="38517" checksum="E7C22474794FA308" modified="2016-11-30" version="1">MAHRTRNMHSGKKPQSKHGFVERFFRVTPTRNAAFISKLFTMVDDESTRDLITWTGSGDQFTVFNNTEFSRVVLPRYFKHCNWSSFVRQLNMYDFHKVNDNNEDDTSDKDNFHNQVQRWDFKHPWFNKAGIDCLHKIRRKPPRNRLIPQMRYSNAMEILPSNSPDNGHRERVHSTSPLAEIPQATTELPNLSNDNSYYHSLPAIMPMPTQMQPKPSMDETVRHLSNHIGTMEQKLDHTSKEVDYLKKTVAIQQEMLEELMSTINQLKSARPQNTNDPVNEFNQYYSTAQPARKPRKIHELLGSGVEPQQNMHINNEVQLKRKRTTKAEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-06-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N8G3</accession>
    <name>A0A1C7N8G3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_07034</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000455">
        <property type="protein sequence ID" value="OBZ84919.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N8G3"/>
    <dbReference type="InParanoid" id="A0A1C7N8G3"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ84919.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="97" mass="10825" checksum="6D1503FD626AF6DA" modified="2016-11-30" version="1">MHPPYTLVVVSVGVLDGYSTFRPDHSSCSHTKSHAIYCLIVPETIVDSLSFLLNLLSTCCPKSFQSITFNTPRSQPSPPAYLKQRFSNMFLSSHPIH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N8P0</accession>
    <name>A0A1C7N8P0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_06449</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000389">
        <property type="protein sequence ID" value="OBZ85505.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N8P0"/>
    <dbReference type="InParanoid" id="A0A1C7N8P0"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ85505.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="64" mass="6775" checksum="BB39E2887352A6FA" modified="2016-11-30" version="1">MAARPNLPDTDGSKEQLILPSETDAVTKDNQLEKAVIDSADQGSAASYGMIVRKDGSILCMSYG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N966</accession>
    <name>A0A1C7N966_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DUF7719 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">A0J61_06277</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000372">
        <property type="protein sequence ID" value="OBZ85672.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N966"/>
    <dbReference type="STRING" id="101091.A0A1C7N966"/>
    <dbReference type="InParanoid" id="A0A1C7N966"/>
    <dbReference type="OrthoDB" id="5597489at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056136">
        <property type="entry name" value="DUF7719"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37846:SF1">
        <property type="entry name" value="DEACETYLASE-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37846">
        <property type="entry name" value="YALI0B21296P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24841">
        <property type="entry name" value="DUF7719"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="134"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="172"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="domain" description="DUF7719" evidence="3">
        <location>
            <begin position="136"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF24841"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OBZ85672.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="203" mass="23090" checksum="602D030951479867" modified="2016-11-30" version="1">MGKKQSGGIKPSEYKKKGPSQPLIDKIPTNKKSNKDDIPDDEKLRLIDQTGLLQKVKQREQEIEQQSTTTAEYVWQAVFLSIPFAFLMGTFDVTVKVQYNEPWDYAGLLTRCVKSAPALAPIIYLTNRYKAKRLTQFLMSLGSVFLGSFLMYTLHRSPSLGQMMRAPGLATIWIYFIVQLDLLPAVITLGIVFAYWFFGLRVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NA03</accession>
    <name>A0A1C7NA03_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">small monomeric GTPase</fullName>
            <ecNumber evidence="2">3.6.5.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">Rala_1</name>
        <name evidence="12" type="ORF">A0J61_06065</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Lipid-anchor</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="11">Endomembrane system</location>
            <topology evidence="11">Lipid-anchor</topology>
            <orientation evidence="11">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.5.2" evidence="2"/>
    <dbReference type="EMBL" id="LUGH01000349">
        <property type="protein sequence ID" value="OBZ85880.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NA03"/>
    <dbReference type="STRING" id="101091.A0A1C7NA03"/>
    <dbReference type="InParanoid" id="A0A1C7NA03"/>
    <dbReference type="OrthoDB" id="5976022at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003925">
        <property type="term" value="F:G protein activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04139">
        <property type="entry name" value="RalA_RalB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000203">
        <property type="entry name" value="Putative ras-related protein ral-a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001806">
        <property type="entry name" value="Small_GTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020849">
        <property type="entry name" value="Small_GTPase_Ras-type"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24070">
        <property type="entry name" value="RAS, DI-RAS, AND RHEB FAMILY MEMBERS OF SMALL GTPASE SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00071">
        <property type="entry name" value="Ras"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00449">
        <property type="entry name" value="RASTRNSFRMNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00175">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00176">
        <property type="entry name" value="RAN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00173">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00174">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51419">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51421">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51420">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0488">Methylation</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-0636">Prenylation</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023289"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00046278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="OBZ85880.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="195" mass="22284" checksum="E1992D018B88355D" modified="2016-11-30" version="1">MAKSKAKQTLPLHKIIMVGSGGVGKSALTLQYMYGDFVEEYDPTKADSYRKKVVLDGQECQIDILDTAGQEEYAAIRDNYYRSGEGFLCVFSVCEQESLEHTQEFRDQILRVLDDETIPFILVGNKVDLAHLRKVPATEANTLAQEWHCPYIETSAKTRQNVEEVYTMLMRQIRDRKAKQQQQHSPDKDSCCVIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NA18</accession>
    <name>A0A1C7NA18_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">alanine--glyoxylate transaminase</fullName>
            <ecNumber evidence="3">2.6.1.44</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">AGX1</name>
        <name evidence="12" type="ORF">A0J61_06061</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 8 10">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.6.1.44" evidence="3"/>
    <dbReference type="EMBL" id="LUGH01000348">
        <property type="protein sequence ID" value="OBZ85890.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NA18"/>
    <dbReference type="STRING" id="101091.A0A1C7NA18"/>
    <dbReference type="InParanoid" id="A0A1C7NA18"/>
    <dbReference type="OrthoDB" id="7403325at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005777">
        <property type="term" value="C:peroxisome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008453">
        <property type="term" value="F:alanine-glyoxylate transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004760">
        <property type="term" value="F:L-serine-pyruvate transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019265">
        <property type="term" value="P:glycine biosynthetic process, by transamination of glyoxylate"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.1150.10:FF:000049">
        <property type="entry name" value="Alanine-glyoxylate aminotransferase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.640.10:FF:000027">
        <property type="entry name" value="Serine--pyruvate aminotransferase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000192">
        <property type="entry name" value="Aminotrans_V_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020578">
        <property type="entry name" value="Aminotrans_V_PyrdxlP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024169">
        <property type="entry name" value="SP_NH2Trfase/AEP_transaminase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21152:SF24">
        <property type="entry name" value="ALANINE--GLYOXYLATE AMINOTRANSFERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21152">
        <property type="entry name" value="AMINOTRANSFERASE CLASS V"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00266">
        <property type="entry name" value="Aminotran_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000524">
        <property type="entry name" value="SPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00595">
        <property type="entry name" value="AA_TRANSFER_CLASS_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 12" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="6 8" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 12" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotransferase class V" evidence="11">
        <location>
            <begin position="29"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="344"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="8">
        <location>
            <position position="192"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR000524-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR000524-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU004075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU004504"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="OBZ85890.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="377" mass="40951" checksum="114964C9B93AC079" modified="2016-11-30" version="1">MAPHKLCMIPGPIEFHEDVLAAMSTPATSHVDPNFIPVFGESIEMVRKVVLTETAQPFIVSGSCTLGWDMMVNLLEKGDEVLALNTGYFGDHFSECLEVYGANVTTLRAEVGSRPSNEALKKALGEKKYKMVTVTHVDTSTGVLSDIKAVAQTVKSISPDTLVIVDGVCSLGSEEIRFDEWGLDIVISGSQKGLGVPPGLSVVVASQQALEVYKSRSTPIVSYYSNWNKWLPIMQAYESRKPAYFATPAVQLIYALHASLKAITSQSMDVRFAKHREVAAKFRETIRDLGLKTLAQCEECSANGMTAVWLPEGIEIPQLVPALANKGVQIAGGILNGLAGKYFRIGHMGISVMEPERGHIDKVVEALSQSLKELQKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NAE5</accession>
    <name>A0A1C7NAE5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">NmrA-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">A0J61_05869</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the NmrA-type oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000330">
        <property type="protein sequence ID" value="OBZ86077.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NAE5"/>
    <dbReference type="InParanoid" id="A0A1C7NAE5"/>
    <dbReference type="OrthoDB" id="9997102at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008030">
        <property type="entry name" value="NmrA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051164">
        <property type="entry name" value="NmrA-like_oxidored"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42748">
        <property type="entry name" value="NITROGEN METABOLITE REPRESSION PROTEIN NMRA FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42748:SF22">
        <property type="entry name" value="NMRA-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05368">
        <property type="entry name" value="NmrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NmrA-like" evidence="3">
        <location>
            <begin position="7"/>
            <end position="294"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF05368"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OBZ86077.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="348" mass="38655" checksum="A06432617D10B75B" modified="2016-11-30" version="1">MSQQVGKGSIFVSGTDGDKGVAIVQQLLQLPEQYKHLTRQDVFAGLPDDTTPRAKSLQGLGAQVVAFDIFHDHQAAVKALTGMTKLCLLIDPLSERLQRSNAYHYGKAFIDAAKEAHVEHVIFLTPFTPSDTCLIKAQEQNASEVMPFDSYRSQFVLIESYLHAQFDNSQITILRYPGVLHQHLLVFGKYIAQHNAFPLPDQHLEITVESCNMIDIARAVACVAHSPTLRHSKNAYKISSGLLTLEEVSQRVLQGLSRENAINRIDVTALQQILSEGIGNEDHALFLMEMWGLVQQKLGNRRLEITRDLEALTGQSGKTLNEYLLEAEVRDAFLSHSNDVLPSSSKVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NAJ3</accession>
    <name>A0A1C7NAJ3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Peptidoglycan-N-acetylglucosamine deacetylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">pgdA_0</name>
        <name evidence="8" type="ORF">A0J61_05804</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Co(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:48828"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000325">
        <property type="protein sequence ID" value="OBZ86142.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NAJ3"/>
    <dbReference type="STRING" id="101091.A0A1C7NAJ3"/>
    <dbReference type="InParanoid" id="A0A1C7NAJ3"/>
    <dbReference type="OrthoDB" id="2125469at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016810">
        <property type="term" value="F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.370">
        <property type="entry name" value="Glycoside hydrolase/deacetylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011330">
        <property type="entry name" value="Glyco_hydro/deAcase_b/a-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002509">
        <property type="entry name" value="NODB_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46471">
        <property type="entry name" value="CHITIN DEACETYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46471:SF4">
        <property type="entry name" value="CHITIN DEACETYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01522">
        <property type="entry name" value="Polysacc_deac_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88713">
        <property type="entry name" value="Glycoside hydrolase/deacetylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51677">
        <property type="entry name" value="NODB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008889568" evidence="6">
        <location>
            <begin position="18"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="domain" description="NodB homology" evidence="7">
        <location>
            <begin position="56"/>
            <end position="252"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OBZ86142.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="265" mass="29540" checksum="F9B907D74C5752CC" modified="2016-11-30" version="1">MLFSAAFTLAMATLAMGAPVTSTDANTENYSAPAPVEAPTGSNVQDGVYLSCNRPGVFALSFDDGPYQYSWDLAKSLKEQNITATFFINGNNWVNVETDSVETSDGQKTYMEVIAHYKEMGHEVASHTYEHKVLAGLSAEDVEYQMNTQSDIIKKAIGLRPAIMRPPTGAYDDNVLATLRKLGYAVVNWDVDTNDWRNHNFEEEKAAYQTMDQDTPQSIGHITLEHEVFEQTVNELVPWAIEYIKSKNYEFVTVSDCLGVPAYYS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NAL9</accession>
    <name>A0A1C7NAL9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">CigA protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_05883</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000332">
        <property type="protein sequence ID" value="OBZ86060.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NAL9"/>
    <dbReference type="STRING" id="101091.A0A1C7NAL9"/>
    <dbReference type="InParanoid" id="A0A1C7NAL9"/>
    <dbReference type="OrthoDB" id="1882547at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd11296">
        <property type="entry name" value="O-FucT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11350">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36050">
        <property type="entry name" value="O-FUCOSYLTRANSFERASE 30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36050:SF1">
        <property type="entry name" value="O-FUCOSYLTRANSFERASE 30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008889571" description="CigA protein" evidence="1">
        <location>
            <begin position="23"/>
            <end position="510"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ86060.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="510" mass="59126" checksum="E660E0EB40549464" modified="2016-11-30" version="1">MKRREATAVIAVLLFLVGCVVLFQHQSSAWSTIKLSSRKKKEPIPVVFPKPFELHQPDFGSEKFLSYFPHSGFHNQRIELENALLLAAYLNRTLLVPSVYLASPAMPWLRFEKLHERLLFQTKEGLDHCVALDTAGMPLPNECLNNFRWTNVPWSFFYNMSSINQQIVPLVFRPGLDYEWLYDTFGLEQNDIYYFKDLSPYEYQIHDDKTQQLPLDRFNYRIDLVTLEKIDHRVLQFGSMFGSYRILAETAEHTELLRKIRSHMIFGHPVLSGAAERIVQQLGGANEFVGMHVRVGDGIFKLRASILIDDIYHTLVDRFTDLTVEQTADYEGGVEQHDLDRTESAEYEIKLRTFHPVDTANYSKPIEVHHPTKPDVHHPRLAQRLECQKGDQVTQRFKNTVLYIATDAPDPRNHPLLRKIFKVFPCSFTLSDFLEDLEDIKRLEVVEERVRLESFLIPMVDAMIAAHGHTFLGTPHSTFTSYIERQLQPAYTGKQVQVMGLEDYLQMMAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NB29</accession>
    <name>A0A1C7NB29_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Glucosamine 6-phosphate N-acetyltransferase</fullName>
            <ecNumber evidence="8">2.3.1.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">gna1_0</name>
        <name evidence="10" type="ORF">A0J61_05671</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>D-glucosamine 6-phosphate + acetyl-CoA = N-acetyl-D-glucosamine 6-phosphate + CoA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:10292"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="ChEBI" id="CHEBI:57513"/>
            <dbReference type="ChEBI" id="CHEBI:58725"/>
            <dbReference type="EC" id="2.3.1.4"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="8">Nucleotide-sugar biosynthesis; UDP-N-acetyl-alpha-D-glucosamine biosynthesis; N-acetyl-alpha-D-glucosamine 1-phosphate from alpha-D-glucosamine 6-phosphate (route I): step 1/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Endoplasmic reticulum membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the acetyltransferase family. GNA1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.4" evidence="8"/>
    <dbReference type="EMBL" id="LUGH01000313">
        <property type="protein sequence ID" value="OBZ86283.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NB29"/>
    <dbReference type="FunCoup" id="A0A1C7NB29">
        <property type="interactions" value="200"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NB29"/>
    <dbReference type="InParanoid" id="A0A1C7NB29"/>
    <dbReference type="OrthoDB" id="10039976at2759"/>
    <dbReference type="UniPathway" id="UPA00113">
        <property type="reaction ID" value="UER00529"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004343">
        <property type="term" value="F:glucosamine 6-phosphate N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006048">
        <property type="term" value="P:UDP-N-acetylglucosamine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd04301">
        <property type="entry name" value="NAT_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.630.30:FF:000048">
        <property type="entry name" value="Glucosamine 6-phosphate N-acetyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039143">
        <property type="entry name" value="GNPNAT1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13355">
        <property type="entry name" value="GLUCOSAMINE 6-PHOSPHATE N-ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13355:SF11">
        <property type="entry name" value="GLUCOSAMINE 6-PHOSPHATE N-ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="5" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8 10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="9">
        <location>
            <begin position="24"/>
            <end position="174"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004586"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU365086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OBZ86283.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="174" mass="19989" checksum="90DAAAE0AF8A0BE1" modified="2016-11-30" version="1">MSEVSLFESNLLSPEVQAALPKGYTLRALRSNDYERGFLEVLKVLTEVGGHTKEEFLDQFNYMKQHNDQYFTITISDDAQNKVVAVGTILVERKFIRKNGLVGHIEDIAVDSNQQGKKLGLRIIQALKYIGAQRGCYKVILDCSEKNIPFYEKCGFKQKEYEMAWYVPKEKARL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NB50</accession>
    <name>A0A1C7NB50_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_07388</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000495">
        <property type="protein sequence ID" value="OBZ84564.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NB50"/>
    <dbReference type="InParanoid" id="A0A1C7NB50"/>
    <dbReference type="OrthoDB" id="2385978at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="21"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="63"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="96"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="170"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="308"/>
            <end position="330"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ84564.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="330" mass="36808" checksum="E3E0AE23E17D6649" modified="2016-11-30" version="1">MYSGPIPPPLPPRPPRCCGCIPLRLGCGIICLIWAAFSMYMAVLSFQNSSLFYSYMPSAPITVFGVANLILSLVSIGGIIVLMTNFSPYVHTLSHAIFVSVFIVLVDTFVNIVLFITSQSNYYSSCTNTSSNRITLDLTSSTNSTLPAFDFSNDYYNCRHLWEDELKFGIVFYILMLAFYSYWALCIYSYSLVLRGYAAELEYRFGGNVPMMSSGVALPPNAILNATTQAGTFPPNDRSVIVLNNAKPKSNETAKKRTDTFSFRNMKRASTVAPYQEEALLVPFHDTRNAQFTIGFRLGPDGNIIDIENAPSPNPRQSQLKRKPVKDEDY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NBJ2</accession>
    <name>A0A1C7NBJ2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Transcriptional regulator prz1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">prz1_5</name>
        <name evidence="11" type="ORF">A0J61_05944</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000337">
        <property type="protein sequence ID" value="OBZ86006.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NBJ2"/>
    <dbReference type="STRING" id="101091.A0A1C7NBJ2"/>
    <dbReference type="InParanoid" id="A0A1C7NBJ2"/>
    <dbReference type="OrthoDB" id="8922241at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000977">
        <property type="term" value="F:RNA polymerase II transcription regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000446">
        <property type="entry name" value="Zinc finger protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050717">
        <property type="entry name" value="C2H2-ZF_Transcription_Reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14196">
        <property type="entry name" value="ODD-SKIPPED - RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14196:SF0">
        <property type="entry name" value="PROTEIN BOWEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="7" id="KW-0804">Transcription</keyword>
    <keyword evidence="6" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 9" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="10">
        <location>
            <begin position="185"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="10">
        <location>
            <begin position="213"/>
            <end position="244"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="OBZ86006.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="259" mass="29709" checksum="A248378D13171AB7" modified="2016-11-30" version="1">MNNYLYTRNFTVVDQTFTLYNNQPYTKDFGSVMSNDYWTDDTTGFLDDCSFPTTFTTQPSMLTSSFTYPTLHSPSSTEFLTASQNTFPESVSASSSTRSSISLDSTPFLPIEHITSTTEAFIAQQQQQVPFVIDQTQFPVAERRQRNMRTELSKEVAEQPSLSKLGSFGTNYYHNETVKEKRKAYSCEHCKRSFARQYDVARHSRIHTGAKPYVCPCCQKAFARSDARIRHFRTEINCMEGAKKIKRYQHSKARPNMSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NBP4</accession>
    <name>A0A1C7NBP4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">DNA replication licensing factor MCM6</fullName>
            <ecNumber evidence="12">3.6.4.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="primary">mcm6</name>
        <name evidence="15" type="ORF">A0J61_05446</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Acts as component of the MCM2-7 complex (MCM complex) which is the replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.12"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="12">Component of the MCM2-7 complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 12">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the MCM family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.12" evidence="12"/>
    <dbReference type="EMBL" id="LUGH01000293">
        <property type="protein sequence ID" value="OBZ86512.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NBP4"/>
    <dbReference type="FunCoup" id="A0A1C7NBP4">
        <property type="interactions" value="712"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NBP4"/>
    <dbReference type="InParanoid" id="A0A1C7NBP4"/>
    <dbReference type="OrthoDB" id="1744952at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000785">
        <property type="term" value="C:chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071162">
        <property type="term" value="C:CMG complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042555">
        <property type="term" value="C:MCM complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097373">
        <property type="term" value="C:MCM core complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005656">
        <property type="term" value="C:nuclear pre-replicative complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043596">
        <property type="term" value="C:nuclear replication fork"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033679">
        <property type="term" value="F:3'-5' DNA/RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003688">
        <property type="term" value="F:DNA replication origin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009378">
        <property type="term" value="F:four-way junction helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990518">
        <property type="term" value="F:single-stranded 3'-5' DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003727">
        <property type="term" value="F:single-stranded RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006270">
        <property type="term" value="P:DNA replication initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006271">
        <property type="term" value="P:DNA strand elongation involved in DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000727">
        <property type="term" value="P:double-strand break repair via break-induced replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902969">
        <property type="term" value="P:mitotic DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006267">
        <property type="term" value="P:pre-replicative complex assembly involved in nuclear cell cycle DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006279">
        <property type="term" value="P:premeiotic DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd17757">
        <property type="entry name" value="MCM6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.20.28.10:FF:000003">
        <property type="entry name" value="DNA helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000115">
        <property type="entry name" value="DNA helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.870">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.28.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1640.10">
        <property type="entry name" value="mini-chromosome maintenance (MCM) complex, chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031327">
        <property type="entry name" value="MCM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008049">
        <property type="entry name" value="MCM6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041024">
        <property type="entry name" value="Mcm6_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018525">
        <property type="entry name" value="MCM_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001208">
        <property type="entry name" value="MCM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041562">
        <property type="entry name" value="MCM_lid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027925">
        <property type="entry name" value="MCM_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033762">
        <property type="entry name" value="MCM_OB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11630">
        <property type="entry name" value="DNA REPLICATION LICENSING FACTOR MCM FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11630:SF43">
        <property type="entry name" value="DNA REPLICATION LICENSING FACTOR MCM6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00493">
        <property type="entry name" value="MCM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17855">
        <property type="entry name" value="MCM_lid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14551">
        <property type="entry name" value="MCM_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17207">
        <property type="entry name" value="MCM_OB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18263">
        <property type="entry name" value="WHD_MCM6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01657">
        <property type="entry name" value="MCMFAMILY"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01662">
        <property type="entry name" value="MCMPROTEIN6"/>
    </dbReference>
    <dbReference type="SMART" id="SM00350">
        <property type="entry name" value="MCM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00847">
        <property type="entry name" value="MCM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50051">
        <property type="entry name" value="MCM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10 12" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="3 12" id="KW-0235">DNA replication</keyword>
    <keyword evidence="8 11" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6 12" id="KW-0347">Helicase</keyword>
    <keyword evidence="5 12" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MCM C-terminal AAA(+) ATPase" evidence="14">
        <location>
            <begin position="419"/>
            <end position="625"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="15"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="377"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="15"/>
            <end position="33"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU004070"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU368064"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50051"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="OBZ86512.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="882" mass="99187" checksum="F092AFC9B02103C9" modified="2016-11-30" version="1">MTDLPSDQLLSGMLDSQVQPMASDSHIPPNTNMEIDESQAPSAQRRPPGGYAPENISRVVDETAMAVMETFEKFLETYKGDQSMYIANSTSSWFGYPYMMQLENFKYSEIDTLFVDFAHIEATDVPLATAIREQYYRFLPYLRRAVHNIVRNHFPDNLYVNEPTLTSTQGGTFRDFTVAFYGLQEQNRVRQLKTDKIGHLISVSGTVTRTSEVRPELVYASFTCNECGKIVNDVEQEFRYTEPTMCQGPTCYNRSSWSLNIEQSKFVDWQRIRIQENANEIPTGSMPRSMDMIVRNEMVERAKAGDKCIFTGTLIVVPDVSAFRTPGTSVETQRDTSNRANEGIASEGVTGLKALGVRDLTYKLSFLACMVQPATNNKANGSNLHGEDQDDEDQRDVYSDLSQKEIEDLRAMVNLGGAIYGKLVNSIAPTVFGHDTVKKGILLQLMGGVHKVTPEGMNLRGDINVCIVGDPSTSKSQFLKYVCSIMPRAVYTSGKASSAAGLTASVVKDEETGEFSIEAGALMLADNGICAIDEFDKMDIKDQVAIHEAMEQQTISIAKAGIQASLNARTSILAAANPVSGRYNKKLTLRQNINMSAPIMSRFDLFFVVLDECNDITDYNIGRHIVNTHRLRDDFMQPEFSTEQIQNYIRYARTFKPQMTPEAAEKLANCYKELRQGDSQGIGRNSYRITVRQLESMIRLSEAIARVNCREEITEAYVAEAFNLLQKSIIRVEEEDVYIDENMEEDDLMTSTEALNGMSLNDNVEQQTGDTATAPAGKISITYEKFEQIKLMLAHKLRMVQQSSDEDPGMRRSELVMWYLEQCEADMVDDDLEQETVIVQKIIKKLLKTDETLIEIRQGETEEELEDPIIMLHPNCVLADEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NBR7</accession>
    <name>A0A1C7NBR7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Mesaconyl-C(4)-CoA hydratase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">meh</name>
        <name evidence="7" type="ORF">A0J61_05411</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000291">
        <property type="protein sequence ID" value="OBZ86535.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NBR7"/>
    <dbReference type="STRING" id="101091.A0A1C7NBR7"/>
    <dbReference type="InParanoid" id="A0A1C7NBR7"/>
    <dbReference type="OrthoDB" id="3257538at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019171">
        <property type="term" value="F:(3R)-hydroxyacyl-[acyl-carrier-protein] dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.2220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.129.10">
        <property type="entry name" value="Hotdog Thioesterase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029069">
        <property type="entry name" value="HotDog_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052741">
        <property type="entry name" value="Mitochondrial_HTD2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002893">
        <property type="entry name" value="Znf_MYND"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28152">
        <property type="entry name" value="HYDROXYACYL-THIOESTER DEHYDRATASE TYPE 2, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28152:SF1">
        <property type="entry name" value="HYDROXYACYL-THIOESTER DEHYDRATASE TYPE 2, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13181">
        <property type="entry name" value="TPR_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01753">
        <property type="entry name" value="zf-MYND"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144232">
        <property type="entry name" value="HIT/MYND zinc finger-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54637">
        <property type="entry name" value="Thioesterase/thiol ester dehydrase-isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50865">
        <property type="entry name" value="ZF_MYND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0802">TPR repeat</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="repeat" description="TPR" evidence="5">
        <location>
            <begin position="176"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="domain" description="MYND-type" evidence="6">
        <location>
            <begin position="346"/>
            <end position="391"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OBZ86535.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="660" mass="75330" checksum="5E1CF32788111F4A" modified="2016-11-30" version="1">MTEVVATTPAPVVENNEVVENAEYQDRFLEGSQRIVPYDLLEARGNADKSNDPDAKNYRDAKELFRKGYELCMTVPRSLEDDVLEKHEEDIKTASETMVQAWLLDDRAAPMSERILILGQQYEKVLLKNIPEEQKEGFFVKESLLFSAWILLVGKQFKHCITTLTLAIDTYDDLPARVYFLRASCHLSLNKLRLGIKDLEKALEKDPKFSVAYFVLGSVYLSMENERENAIKNYKLYIQNGHSDSNETVHALYALSVLVNFKKRKPEAREYYEKAKKAEEHFKELYGANTGLSETKRNAILAHESPEEAERLISVYAPKKQMDQRMQQLIQSGILNQSFPPNPKRCSHCAATHVKDKPESPLLACGACRSIWYCSRDCQVADYRASHKSQSQRVHDWERLTKQHVSITHDHIVASPHNLLTNTLNPQVVNASSLAPDGTPLPPCYHHVYFPPRTPEPELAHDGYETDFFPPSPFSQRMWAGAEFSWSQSNPLSIGDQAKMTTQLDTVQLREGRMGESVMVWINKDIENQHGWCMRERRCLVYHPTQQGLSTSPPTVRGIPVKKEPDFSLTMTPSSILLFRYSALTFNSHKIHYDHLYATQIENHPACLVHGPLSGTLLTHLLSDKIKLGQWKQFSYKCLMPLYVNQPLTVAAKQSNKGQH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NBZ7</accession>
    <name>A0A1C7NBZ7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">JmjC domain-containing protein 7</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">Jmjd7</name>
        <name evidence="2" type="ORF">A0J61_05318</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000284">
        <property type="protein sequence ID" value="OBZ86633.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NBZ7"/>
    <dbReference type="STRING" id="101091.A0A1C7NBZ7"/>
    <dbReference type="InParanoid" id="A0A1C7NBZ7"/>
    <dbReference type="OrthoDB" id="415358at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="entry name" value="Jelly Rolls"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041667">
        <property type="entry name" value="Cupin_8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003347">
        <property type="entry name" value="JmjC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12461:SF99">
        <property type="entry name" value="BIFUNCTIONAL PEPTIDASE AND (3S)-LYSYL HYDROXYLASE JMJD7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12461">
        <property type="entry name" value="HYPOXIA-INDUCIBLE FACTOR 1 ALPHA INHIBITOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13621">
        <property type="entry name" value="Cupin_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00558">
        <property type="entry name" value="JmjC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51184">
        <property type="entry name" value="JMJC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="JmjC" evidence="1">
        <location>
            <begin position="131"/>
            <end position="313"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ86633.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="332" mass="38333" checksum="B6F2F9E071C1B292" modified="2016-11-30" version="1">MLLSSTTNRLSCFETLSQTRDEINGTSIRIYSKPPSPLEFLRESVHPNRPAIIKGAFDHWPARTQWTNDYLRSKMEDTIVTVATTPNGYADAVTYDPVHQKDYFVMPHEAHMSFNAFLDLVEGKQQSENAHYISLQNGSLSIEYGPLEQDVDPEIDWCSEALGKQPDAVNFWFGDEKSITSLHKDPYENCYAVIRGQKTFVLYPPSEYYCMHESMYPNAQYAPDPITGQLVIKPLESKTPWIPVDPLNPDFDRFPRFRHARPITVTVEEGEMLYLPALWFHQVLQKGEEGVIAINYWYDMDYRHSLFSTVGLFRRWMTGVVEGNPELLEDME</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NC10</accession>
    <name>A0A1C7NC10_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_05295</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000282">
        <property type="protein sequence ID" value="OBZ86653.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NC10"/>
    <dbReference type="InParanoid" id="A0A1C7NC10"/>
    <dbReference type="OrthoDB" id="2246723at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="14"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ86653.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="229" mass="26472" checksum="6AB484D23C885F1F" modified="2016-11-30" version="1">MMNLMNMMNTWRNEEEDEVEDDDEEEQSEKKRKRKIDHSENDVLLVVKMLLDTIFGDTKLKWKSGEKTTDATKRARIVGQLLSRGTSCSNLMGRRSDLVLYNKSNVVLCLSELKDGNSESNSIKQEAKSLRCSKSLLSYNKPFSQKDIWSLDWNGFSGYTYYLKSYNDVTVVLPGRSLSIPLVKDSIDDFEDTLIALYEFKEHMLEYDHSLSQEFTASMSDELKVYHSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NCH5</accession>
    <name>A0A1C7NCH5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">CCHC-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_05131</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000269">
        <property type="protein sequence ID" value="OBZ86822.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NCH5"/>
    <dbReference type="STRING" id="101091.A0A1C7NCH5"/>
    <dbReference type="InParanoid" id="A0A1C7NCH5"/>
    <dbReference type="OrthoDB" id="2288923at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.60.10">
        <property type="entry name" value="Zinc finger, CCHC-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001878">
        <property type="entry name" value="Znf_CCHC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036875">
        <property type="entry name" value="Znf_CCHC_sf"/>
    </dbReference>
    <dbReference type="SMART" id="SM00343">
        <property type="entry name" value="ZnF_C2HC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57756">
        <property type="entry name" value="Retrovirus zinc finger-like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50158">
        <property type="entry name" value="ZF_CCHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="CCHC-type" evidence="2">
        <location>
            <begin position="250"/>
            <end position="265"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ86822.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="461" mass="50727" checksum="9AFCEF5FB78855A7" modified="2016-11-30" version="1">MSSAILPRAWVSVVRDADTTQTSLFSQNNPQEDDFSQGAQTPFLKGSLPESVFIDITNVKDIKLFFSGLITLCSPNDQIWKPLAIEATTNGLPSFQAPFSAFDVLSGDVKILKISISGLICGFQFYLSTECNMKYGQTDGGAAELKSDMMSNLSPFGRVVDCGLVQGIAGTFTGRGFVVLEVGLSSSNQLQHEVHWKYTYLSARGNLANSYSEAIKMHATWAKTNPFYRYCHKQEYVVTNRPTRHASLVCYHCHERVHIAKDCPKKNAARKGVHPPVVAEPLEPQTPIISHVPSVVSSVELTANEASSLFSVRTIPQLVIRTSKTVDPRPFLPSEPMSLVVDNATDLLTSESDVTGLLLTSSVPVCIACGQSDHKRRNHNSCPLNSKNVNASLSEKTVNSMEIPQTSGMDLDPRSSPSLIIPLQVMVTLVNHNHSKCDDHEFRQQYGQFTLTRWCILGYSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NCL5</accession>
    <name>A0A1C7NCL5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_05076</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000264">
        <property type="protein sequence ID" value="OBZ86872.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NCL5"/>
    <dbReference type="InParanoid" id="A0A1C7NCL5"/>
    <dbReference type="OrthoDB" id="2218707at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="179"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="258"/>
            <end position="268"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ86872.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="340" mass="38903" checksum="A4D8A0109CED86E1" modified="2016-11-30" version="1">MYFNVEEINHLFLKDQWATKANLICRLFKAHSIDFMKATKTGQIYVMKNTMMLIARLFNAYCLAELCKLTSEEIMVGHIIEPLLNAIQDVVLWSPSTTFELSGLESDISLEPLTGDEWIFHAQPENRPISSTKSIYSHHPLYQWLSFDLSGQPNSPDMIQTLMSVAKIKRQQQAIIETRQRQSAFIRPTPSYPKKQKASRLQYRKQPPLYHKGSHETDHRSCHSKTALPPSPPHKKRKSIYQSDPIPIKKRLEDDQETLPSLSTSTSDTTHDSYQQYLIDHGNDNLNLLATQATQLRGLPLSPEISPSPPPIVFKQQQDNLLRLPSLQTILTELNCSLPF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7ND14</accession>
    <name>A0A1C7ND14_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Mediator of RNA polymerase II transcription subunit 25</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">med25</name>
        <name evidence="5" type="ORF">A0J61_04928</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the Mediator complex subunit 25 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000252">
        <property type="protein sequence ID" value="OBZ87022.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7ND14"/>
    <dbReference type="STRING" id="101091.A0A1C7ND14"/>
    <dbReference type="InParanoid" id="A0A1C7ND14"/>
    <dbReference type="OrthoDB" id="7690434at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016592">
        <property type="term" value="C:mediator complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005667">
        <property type="term" value="C:transcription regulator complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021419">
        <property type="entry name" value="Mediator_Med25_VWA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036465">
        <property type="entry name" value="vWFA_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12433">
        <property type="entry name" value="MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12433:SF11">
        <property type="entry name" value="MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11265">
        <property type="entry name" value="Med25_VWA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53300">
        <property type="entry name" value="vWA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Mediator of RNA polymerase II transcription subunit 25 von Willebrand factor type A" evidence="4">
        <location>
            <begin position="33"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="250"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="299"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="327"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="338"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="360"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="422"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00019694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF11265"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OBZ87022.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="422" mass="47202" checksum="A63A9495B0259FE4" modified="2016-11-30" version="1" fragment="single">MSTPAADPSNTVSHLGSHTSPAPTPQVHAHQRKEVAVVFVVDGTARMRPYFKTLYDSYVEPILKQLRTPIVQESEENQTKTKITPMLKYGLVVFGDYEPLSLNTIDRKYFTSDPILFQDIFQNISCEQGGIIKNAVEEGMVAALELFDDYKEGLGGKEFVQHCIVLSNSIPYKMGARCNLMEKYDGLQLNDIAQEMKKSNIRLSLISPQNNCKELEQIVREVNDPKIELSSATAFAAHRVILADPTKAIASGSSQPADTGKKRKRDNLPGQISLPKPAFDGRQFVDPALANRTQPKKQPIKEEPKEDPVEQSLPNQAAVNPSAMVHQQPLQPQQKQQSTHAPIPQNQIGVSQPLQHASPQLQHQQQTQQQQQLQQIQLQQLQQAQAQAQAQAQAQAQAQAQAQQQQQQQQQQQQQQQQQQQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7ND77</accession>
    <name>A0A1C7ND77_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">A0J61_06624</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000409">
        <property type="protein sequence ID" value="OBZ85324.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7ND77"/>
    <dbReference type="FunCoup" id="A0A1C7ND77">
        <property type="interactions" value="293"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7ND77"/>
    <dbReference type="InParanoid" id="A0A1C7ND77"/>
    <dbReference type="OrthoDB" id="2985014at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000057">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791">
        <property type="entry name" value="PERMEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791:SF36">
        <property type="entry name" value="TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_6G08340)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="82"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="111"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="136"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="171"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="205"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="274"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="311"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="342"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="367"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="430"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="8">
        <location>
            <begin position="45"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OBZ85324.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="487" mass="54721" checksum="788532B3FA6CD5FA" modified="2016-11-30" version="1">MSNPKEKTEQDVPSYEENPMDSIVPSDQLNPEVEKKLVRLLDYRLMIWAFFGYFANGLDRNNMPNAETTGLSEDLHLVSNQYNWALTMFFIGYIILQIPANYVITKVRPSIMLPLIVFTWGAVVCFMALVKNFQGLYALRFCLGVAEAGFYPGIVFLIGSWYTKEEIGTRTCIFVAGSQISGAFSGIISGAIAQGLDGVNGMRGWKWLFIIEGLIAVVIGFVGFFVLPDFPHNTRFVQGEMREVAMIRLERQGRSGALTGLNLTTFRNLLATPFIYLFLSMFICMQMGMGILQNFVIILKQTGYSSSTANYLMVPIWVWVSIVVVAQGYLSDKYSHRAYHILGGTLFTLIWYIVLVAVNGGNLPTPLLFVCAYLVVPIYGVSPIMMTWVNETYAVDRESRALAIATINSLGNLAPNFINVKVWDIQDAPAFRLGKIVTMALTGVIMILCCVTLYLQRKKILIPQAPQRVIDEEMNKKKTHIVREDEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NDG2</accession>
    <name>A0A1C7NDG2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Homeobox protein 10</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">hbx10_0</name>
        <name evidence="8" type="ORF">A0J61_05150</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4 5">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000271">
        <property type="protein sequence ID" value="OBZ86799.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NDG2"/>
    <dbReference type="STRING" id="101091.A0A1C7NDG2"/>
    <dbReference type="InParanoid" id="A0A1C7NDG2"/>
    <dbReference type="OrthoDB" id="6159439at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030154">
        <property type="term" value="P:cell differentiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00086">
        <property type="entry name" value="homeodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001356">
        <property type="entry name" value="HD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017970">
        <property type="entry name" value="Homeobox_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051000">
        <property type="entry name" value="Homeobox_DNA-bind_prot"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057939">
        <property type="entry name" value="TRF2_HOY1_PH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24324:SF9">
        <property type="entry name" value="HOMEOBOX DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24324">
        <property type="entry name" value="HOMEOBOX PROTEIN HHEX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00046">
        <property type="entry name" value="Homeodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24818">
        <property type="entry name" value="PH_TRF2_HOY1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00389">
        <property type="entry name" value="HOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00027">
        <property type="entry name" value="HOMEOBOX_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50071">
        <property type="entry name" value="HOMEOBOX_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 4 5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2 4 5" id="KW-0371">Homeobox</keyword>
    <keyword evidence="3 4 5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Homeobox" evidence="7">
        <location>
            <begin position="46"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="Homeobox" evidence="4">
        <location>
            <begin position="48"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="165"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="183"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="204"/>
            <end position="217"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU000682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OBZ86799.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="479" mass="54568" checksum="833351801E4600B7" modified="2016-11-30" version="1">MSSLPNFDPNNSTFAPNQYPTYNDTKMFSFPPPPPIMMPPNFDRDISPPRKRTRTSPEQLAVLEKSFSINPSPNNRVREQLAHQLGMPERSIQIWFQNRRAKVKNQAKRSAQLQDSTLYMQQQYAANAAAAACQSVAYQQQQDSIDPNLYYYYYYYYFHQQSSSPLGEDTKNTMPPPPPPAPSSLQSWSSPSMTPPIQTHLPDLTLSASTSSSSLASDNFRQTHVHRRQHYRSSSASLSERTRAHSVGPYPYYRKSTPQERHSSLGPPTSYYQTNPNTLQNQLLFSNPENRLYNSSTIIEEAYMPMHPPSVKQSQPTSPLSVQNLQIGSWKRVSDLSCHVDLTTRKLIWSIGDDQQSFRIEINLSLVQLIRSYALENTYKIEFYLTSPDQVKFFMTVDGAWVQCHDFTQDKQASSETVHTLEGFSQLQDELMDILMQAPDLQSLVVQDEDKEEGYPLSSTGDDGMTNNLLLLQGLHLPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NDP8</accession>
    <name>A0A1C7NDP8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_04862</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000248">
        <property type="protein sequence ID" value="OBZ87090.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NDP8"/>
    <dbReference type="STRING" id="101091.A0A1C7NDP8"/>
    <dbReference type="InParanoid" id="A0A1C7NDP8"/>
    <dbReference type="OrthoDB" id="4349954at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030490">
        <property type="term" value="P:maturation of SSU-rRNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042859">
        <property type="entry name" value="NOL11"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15633">
        <property type="entry name" value="NUCLEOLAR PROTEIN 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15633:SF2">
        <property type="entry name" value="NUCLEOLAR PROTEIN 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ87090.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="635" mass="70709" checksum="50FD56B0ABCA9665" modified="2016-11-30" version="1">MPGFVLEEPFPLARFHNTIGEKDSKHFVVGLNALDNDASEDIDSVAITVQGEGFKIYNTADQKCTKSWTTPPGIAFVGPATHIVGGRDTDAVDYTYAIVASGPDVAKFEERKSIWVWKNTNNGDNEELDKTTKTYDEPIHAIRVSPSLPAHVILISENGSIELATKDLDRSIAKQKPTNKSDIVWSNVFVTSNAHCCIPSSMVPAMSTIVVTISHAFQSDLYSLKINYVNVERRSIDLLTAIDIKLSEKPTSFTLDPSDGRLTILGSAGTWTVYRMQLRHSSSKKISGSLTEHVSIQLHGYRFQDDVLGNIASVKPLSDSYVAMIAPRTTKKNEIEHVVSVWDVKYGTLQAEQIIKLSEKNTFSKSACTYDIAVLPNSHLAVTVSSVALKTSSKNIKSAKKMVDTSSVIMLCPYYSEPVSLMAAMGKMKNTIIAMGISTDLSSEENIGYARSGKETVSRDFGFNPDEDADQVYDKWVSRLEKYQKNESVTLAKLMSDISADEFSNVFFEYAHITLAKDQQHMTEASLDSIAAQTEQYRHALMQQFNSSTKKKPAELSQFFISHVISKCFDKQDFWPVDVILYLMSRSLLRSNYAEKGIVRSLLERKEWALLPIVLERVQDIPENDLVTLIKALCT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NDQ0</accession>
    <name>A0A1C7NDQ0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Ankyrin repeat-containing protein P16F5.05c</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">A0J61_04744</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000239">
        <property type="protein sequence ID" value="OBZ87205.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NDQ0"/>
    <dbReference type="FunCoup" id="A0A1C7NDQ0">
        <property type="interactions" value="30"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NDQ0"/>
    <dbReference type="InParanoid" id="A0A1C7NDQ0"/>
    <dbReference type="OrthoDB" id="10057496at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24126:SF14">
        <property type="entry name" value="ANK_REP_REGION DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24126">
        <property type="entry name" value="ANKYRIN REPEAT, PH AND SEC7 DOMAIN CONTAINING PROTEIN SECG-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01415">
        <property type="entry name" value="ANKYRIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="39"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="81"/>
            <end position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OBZ87205.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="170" mass="19265" checksum="E4DBAA541862A35E" modified="2016-11-30" version="1">MADHAELLDDIIYFSRAGELDDLKELKASPELFVEKDDTGKTAIHMASANNHVEIVKYILEQFSTLDDKKKAELVNTKNNEGNTPLHWAALNGHLEVVKLLVENGGDCKIKNNMKLTPIYEAQQREHEAIAEYFLNTMIEEEPEEPLEEDKQFVETGYTELTGGSSQKKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NE22</accession>
    <name>A0A1C7NE22_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">N-acetylglucosaminyl-phosphatidylinositol biosynthetic protein gpi1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">gpi1</name>
        <name evidence="2" type="ORF">A0J61_04607</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000229">
        <property type="protein sequence ID" value="OBZ87345.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NE22"/>
    <dbReference type="FunCoup" id="A0A1C7NE22">
        <property type="interactions" value="229"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NE22"/>
    <dbReference type="InParanoid" id="A0A1C7NE22"/>
    <dbReference type="OrthoDB" id="70250at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006506">
        <property type="term" value="P:GPI anchor biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007720">
        <property type="entry name" value="PigQ/GPI1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21329:SF3">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL N-ACETYLGLUCOSAMINYLTRANSFERASE SUBUNIT Q"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21329">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL N-ACETYLGLUCOSAMINYLTRANSFERASE SUBUNIT Q-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05024">
        <property type="entry name" value="Gpi1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="266"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="352"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="412"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="441"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="469"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="517"/>
            <end position="538"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="550"/>
            <end position="573"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ87345.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="664" mass="76690" checksum="2C82855B55863F99" modified="2016-11-30" version="1">MPSQNVVKLFWPSHLCSPKTRQGFIIGWRNTNNKICVASVVSDIELKELQDVLKEFCNSGEYVEYAHINKVCSVPPQILGVLYRSQRCLPILSNIDQEVWLTVMLDHAYVPVIIAAKGKETSHALQTRFAYQVVFYEQPNPKKLQFLALDPLELDISSNDIPVITLNKKQMDVQNHIKTIIDYSHKLNGKTKSDSDELSLVLIQINSSYFLEYGIQTLASNCRKRNGAKYATIAHVLNWIHSIIQRLVQVVITSPKGFIGFFIKKAFAYLFMSILFLALNLAEVTLHLLNVRFPKFILNGVALKDLSAAGQQIDLRLQQFFFWPKQYMMLRKHNWANTASARAHYISFYNSMWLVANDIIIGLAMGSFLMANNRIMAVKLHTMLHTYTVESLQSMMLWFLESPAGLKLNHELGSFLSELFLWLIRLWTLCTQTVEPYTPQIIHFVGLSGIFGITMIISLLSDFLAFMTLHIYCFYMVAARIFNWQLVILSSLFNLFRGKKRNILRDRIDSCDYDLDQLLLGTSLFTLLTFLFPTVLIYYMTFAVGRVSVIFLQAVMETILAFFNHFPLFAIMLRLKDPHRLPGGLEFEIFEHDSFLLEHHGIFHRIRQIWNSFKKFAVHRSSTTQKRSKKVSKRASPSIKTTQHTIEVTKKIESSRGSYFWMRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NEB3</accession>
    <name>A0A1C7NEB3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">DUF202 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">A0J61_04831</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000245">
        <property type="protein sequence ID" value="OBZ87119.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NEB3"/>
    <dbReference type="InParanoid" id="A0A1C7NEB3"/>
    <dbReference type="OrthoDB" id="199599at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003807">
        <property type="entry name" value="DUF202"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052053">
        <property type="entry name" value="IM_YidH-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34187:SF2">
        <property type="entry name" value="DUF202 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34187">
        <property type="entry name" value="FGR18P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02656">
        <property type="entry name" value="DUF202"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="101"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="144"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="185"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="domain" description="DUF202" evidence="7">
        <location>
            <begin position="92"/>
            <end position="172"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02656"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OBZ87119.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="210" mass="23388" checksum="E29427257E268A57" modified="2016-11-30" version="1">MSESSSILACSKTQSNYTAIVSNQILSNDKKNNQKIRLHQAPQNKINDLTMLCSFSEATVKNMDAATVCSLNFSLAKWSTSLYLENKASVARDHLANERTFLAWIRTSLSIISVGIGITQLFHLNKDQLNYSQLLPTWKQSIDSGKLIGLAFIAIGISYIFFAFIRYFHSQTAMTKGCFPASRGIVTITTLSTLFLLVTVFIVILFQKQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NET9</accession>
    <name>A0A1C7NET9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">BZIP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">A0J61_04341</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000210">
        <property type="protein sequence ID" value="OBZ87625.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NET9"/>
    <dbReference type="FunCoup" id="A0A1C7NET9">
        <property type="interactions" value="36"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NET9"/>
    <dbReference type="InParanoid" id="A0A1C7NET9"/>
    <dbReference type="OrthoDB" id="2593073at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090575">
        <property type="term" value="C:RNA polymerase II transcription regulator complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001228">
        <property type="term" value="F:DNA-binding transcription activator activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000976">
        <property type="term" value="F:transcription cis-regulatory region binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033554">
        <property type="term" value="P:cellular response to stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd14688">
        <property type="entry name" value="bZIP_YAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.170">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.100">
        <property type="entry name" value="YAP1 redox domain. Chain B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050936">
        <property type="entry name" value="AP-1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004827">
        <property type="entry name" value="bZIP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046347">
        <property type="entry name" value="bZIP_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013910">
        <property type="entry name" value="TF_PAP1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023167">
        <property type="entry name" value="Yap1_redox_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40621:SF8">
        <property type="entry name" value="AP-1-LIKE TRANSCRIPTION FACTOR YAP3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40621">
        <property type="entry name" value="TRANSCRIPTION FACTOR KAPC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00170">
        <property type="entry name" value="bZIP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08601">
        <property type="entry name" value="PAP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00338">
        <property type="entry name" value="BRLZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57959">
        <property type="entry name" value="Leucine zipper domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111430">
        <property type="entry name" value="YAP1 redox domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50217">
        <property type="entry name" value="BZIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00036">
        <property type="entry name" value="BZIP_BASIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BZIP" evidence="5">
        <location>
            <begin position="71"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="131"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="131"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="158"/>
            <end position="194"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OBZ87625.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="359" mass="40576" checksum="CA6001AB857C23E8" modified="2016-11-30" version="1">MDNQAIRQESTSPSTSAFRPIMPSSTPPKILPRPESLKLNNDQSWIRIPSKRPMKGPNEDVIKLPGVNSTNDLRIRRKEQNRAAQRAFRERKERYVKELEDKIKEIKAAHAIQVAQLEKENQELKLALKRLQNTSPEAASTPNKKQRKRSLSPVGDISSPQFSDTQSPINASPVSTSPRTASPMRTSPINTSPTPRIPSSAVACIRDKDGISFCERLKEEVCSRAYNQLLTEPLFDSHGFLNETISSHPVPIVTTDEEGNECRKSEIFNRMEQDLTDRFLPTQHDASALHKADGFISCSEVWAKISAHPRFEEFDVDELCDEIRKRAKCSRNGPVFEEHDVIEVLETMEAKLNFIAFAC</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NFF7</accession>
    <name>A0A1C7NFF7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Splicing factor U2AF subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">SPAP8A3.06</name>
        <name evidence="8" type="ORF">A0J61_04252</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000204">
        <property type="protein sequence ID" value="OBZ87690.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NFF7"/>
    <dbReference type="FunCoup" id="A0A1C7NFF7">
        <property type="interactions" value="551"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NFF7"/>
    <dbReference type="InParanoid" id="A0A1C7NFF7"/>
    <dbReference type="OrthoDB" id="423462at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000243">
        <property type="term" value="C:commitment complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071004">
        <property type="term" value="C:U2-type prespliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0089701">
        <property type="term" value="C:U2AF complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045292">
        <property type="term" value="P:mRNA cis splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009145">
        <property type="entry name" value="U2AF_small"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000571">
        <property type="entry name" value="Znf_CCCH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12620">
        <property type="entry name" value="U2 SNRNP AUXILIARY FACTOR, SMALL SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00642">
        <property type="entry name" value="zf-CCCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01848">
        <property type="entry name" value="U2AUXFACTOR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50103">
        <property type="entry name" value="ZF_C3H1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 5" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C3H1-type" evidence="7">
        <location>
            <begin position="62"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="5">
        <location>
            <begin position="62"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="112"/>
            <end position="163"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OBZ87690.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="163" mass="19689" checksum="65E13A0B1ED47F0A" modified="2016-11-30" version="1">MELAKFGEVEEMVVCDNVGDHLVGNVYCQFRLEESAGNAVTSLNNRFYAGRPIYAELSPVTDFREACCRQHEISECNRGGFCNFMHLKHPSRQLRRELYEGQRLDIREKRREDVRHDDDDRRARDRDRGRDRERDRDRERDRGDRDRDRDRGEREYPEERMDY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NFI5</accession>
    <name>A0A1C7NFI5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Putative metal ion transporter C17A12.14</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">A0J61_04132</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000195">
        <property type="protein sequence ID" value="OBZ87818.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NFI5"/>
    <dbReference type="STRING" id="101091.A0A1C7NFI5"/>
    <dbReference type="InParanoid" id="A0A1C7NFI5"/>
    <dbReference type="OrthoDB" id="29879at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015095">
        <property type="term" value="F:magnesium ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010961">
        <property type="term" value="P:intracellular magnesium ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd12829">
        <property type="entry name" value="Alr1p-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.460.20">
        <property type="entry name" value="CorA soluble domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.340">
        <property type="entry name" value="Magnesium transport protein CorA, transmembrane region"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044089">
        <property type="entry name" value="Alr1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045861">
        <property type="entry name" value="CorA_cytoplasmic_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045863">
        <property type="entry name" value="CorA_TM1_TM2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002523">
        <property type="entry name" value="MgTranspt_CorA/ZnTranspt_ZntB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21535">
        <property type="entry name" value="MAGNESIUM AND COBALT TRANSPORT PROTEIN/MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21535:SF51">
        <property type="entry name" value="MANGANESE RESISTANCE PROTEIN MNR2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01544">
        <property type="entry name" value="CorA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143865">
        <property type="entry name" value="CorA soluble domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144083">
        <property type="entry name" value="Magnesium transport protein CorA, transmembrane region"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="466"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="499"/>
            <end position="518"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="23"/>
            <end position="32"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009765"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OBZ87818.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="524" mass="60016" checksum="480C8AA6D04322AC" modified="2016-11-30" version="1">MSHHRSSSIRRRGTGNFSIGAEQPNQMRSGSFESDRSHRQSFHSFLKEEVTLQDEELEPEDVKTDVLFPRFTNSGGDRVDMDAFDRMVQDRTRKLSQGTIQLAKQPSRQNQLYRSSVTLDPPLNDIRFRAYSAQQNALTSLYELLTEDGRQALASVVQSKGWWVDVLCPTTEEMRVLSKTFRIHPLTTEDIQAQESREKIELFPNYTFVCFKAIDIDPLTDRIIPFNFYSLIFQDGLLTFHFKNSHHIDRVRERCDQLKEFMPITSDWMNYALIDSITDSFAPIILQVETETVSIDELSLVLKESEKADMLKRISRCRKQSTQLARLLTSKLDVIKSLMKRYEDKLEQHQQHQQASFPLQLNQALAKATLTSPAAARLAPTHHVASGAATPLLFSASPSNPIMETKKAFSDVLLYLGDIQDHVVTMVQNINHYDRILHRAHTNYLAQVNLELTKTYNMTNEVMNRLTFMASVFIPLTLVCSLWGMNVAVPGQNYLDNAYFFWILGGMAVYCTGCLFFGKRVGFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NFT7</accession>
    <name>A0A1C7NFT7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Protein HGH1 homolog</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">hgh1</name>
        <name evidence="5" type="ORF">A0J61_03974</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the HGH1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000184">
        <property type="protein sequence ID" value="OBZ87977.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NFT7"/>
    <dbReference type="FunCoup" id="A0A1C7NFT7">
        <property type="interactions" value="642"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NFT7"/>
    <dbReference type="InParanoid" id="A0A1C7NFT7"/>
    <dbReference type="OrthoDB" id="338814at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061770">
        <property type="term" value="F:translation elongation factor binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039717">
        <property type="entry name" value="Hgh1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007206">
        <property type="entry name" value="Protein_HGH1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007205">
        <property type="entry name" value="Protein_HGH1_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13387">
        <property type="entry name" value="PROTEIN HGH1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13387:SF9">
        <property type="entry name" value="PROTEIN HGH1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04063">
        <property type="entry name" value="DUF383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04064">
        <property type="entry name" value="DUF384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Protein HGH1 N-terminal" evidence="3">
        <location>
            <begin position="96"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="domain" description="Protein HGH1 C-terminal" evidence="4">
        <location>
            <begin position="285"/>
            <end position="338"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006712"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00014076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF04063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF04064"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OBZ87977.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="405" mass="46308" checksum="1EF2B544B45E5C8D" modified="2016-11-30" version="1">MEAQIKELIPFLQQPALEIRAIAVHHLVPYTPNGNQYRYILLEQRATVCKGLKALCKEDPVTAHDALRCLINLSSDPLVQQELDDIDFINYIGLLITNAKSVLADLACMLLSNMTKYEPVCVKVIQATAKPLDDFCSSTRLLDQLVEVFHKGYKKEYNPEAEFHFLASVFSNVSSIRLGRVFMIERAADQLSPLTKIQIFTEDPNVIRRGGADSTIKNCCFETREHTRLLDVNDINVLPFILLPLCGNEEYDIDEFEQFPEEIQMLGDDKKRETDSMLRTLLLESLILLTSTRFGRDYLREKQVYRVIQRLHIQETDEDIKELCVTIVDMLIRDEEGPEVTELEKPKVEEDEDLVIEEIPSFVQAVKSELFSPEKRQGNLNIALSLTVFTGAIVFLRNWGELLAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NFV5</accession>
    <name>A0A1C7NFV5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Phosphotransferase</fullName>
            <ecNumber evidence="6">2.7.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">hxk1_4</name>
        <name evidence="9" type="ORF">A0J61_03989</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the hexokinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.-" evidence="6"/>
    <dbReference type="EMBL" id="LUGH01000185">
        <property type="protein sequence ID" value="OBZ87962.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NFV5"/>
    <dbReference type="STRING" id="101091.A0A1C7NFV5"/>
    <dbReference type="InParanoid" id="A0A1C7NFV5"/>
    <dbReference type="OrthoDB" id="419537at2759"/>
    <dbReference type="UniPathway" id="UPA00109">
        <property type="reaction ID" value="UER00180"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005536">
        <property type="term" value="F:D-glucose binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008865">
        <property type="term" value="F:fructokinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004340">
        <property type="term" value="F:glucokinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019158">
        <property type="term" value="F:mannokinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006006">
        <property type="term" value="P:glucose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006096">
        <property type="term" value="P:glycolytic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001678">
        <property type="term" value="P:intracellular glucose homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006013">
        <property type="term" value="P:mannose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.367.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001312">
        <property type="entry name" value="Hexokinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022673">
        <property type="entry name" value="Hexokinase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022672">
        <property type="entry name" value="Hexokinase_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19443">
        <property type="entry name" value="HEXOKINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19443:SF24">
        <property type="entry name" value="PHOSPHOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00349">
        <property type="entry name" value="Hexokinase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03727">
        <property type="entry name" value="Hexokinase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00475">
        <property type="entry name" value="HEXOKINASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51748">
        <property type="entry name" value="HEXOKINASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="4 6 9" id="KW-0418">Kinase</keyword>
    <keyword evidence="3 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Hexokinase N-terminal" evidence="7">
        <location>
            <begin position="10"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="domain" description="Hexokinase C-terminal" evidence="8">
        <location>
            <begin position="214"/>
            <end position="456"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU362007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00349"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF03727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OBZ87962.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="459" mass="50551" checksum="DA27A32F4625EDB8" modified="2016-11-30" version="1">MTTDSLFQLLQNEFALSKEQLEPIIKGFNLECKKGLKTPSKGLATMIPSYVTRMPTGRETGTFLSLDLGGTNLRVAAVELKGNGKSVVHELKRCPSIELKTGEGAVFFDWIADAIQELVTIEAAHLFSQSQVLNDEPLSLGVCWSFPVDQTAVDRGTILRMGKGFILKNTEGRDLADMFHEAFKRKSMKVKVTAILNDTVGTLVAHGYTNPACRIGLIFATGVNAAYPEKVPQITKLDKNVRDKYSIDTEMLINTEIDIFGTEAYLPLTKYDLALDLSHSQPKFQLYEKMLSGAYLGELTRLIAMDFIKSGALFGGIIPEGFDQTWSFPTMYMSCLESEEATYESSLQILSDFKFAAVPTLNDIAILTRICCVVSTRAASLAAVAIISLIDQQNLFETLQDQIVVGINGSTYEFYPGMNLRVRRSLDEWYGKEKSSRITLEVASEGGSVGGALIAMLCK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NFY9</accession>
    <name>A0A1C7NFY9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Extracellular serine proteinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">SEPR_1</name>
        <name evidence="8" type="ORF">A0J61_05669</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5 6">Belongs to the peptidase S8 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000313">
        <property type="protein sequence ID" value="OBZ86274.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NFY9"/>
    <dbReference type="STRING" id="101091.A0A1C7NFY9"/>
    <dbReference type="InParanoid" id="A0A1C7NFY9"/>
    <dbReference type="OrthoDB" id="206201at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04077">
        <property type="entry name" value="Peptidases_S8_PCSK9_ProteinaseK_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.200">
        <property type="entry name" value="Peptidase S8/S53 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034193">
        <property type="entry name" value="PCSK9_ProteinaseK-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000209">
        <property type="entry name" value="Peptidase_S8/S53_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036852">
        <property type="entry name" value="Peptidase_S8/S53_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023827">
        <property type="entry name" value="Peptidase_S8_Asp-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023828">
        <property type="entry name" value="Peptidase_S8_Ser-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050131">
        <property type="entry name" value="Peptidase_S8_subtilisin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015500">
        <property type="entry name" value="Peptidase_S8_subtilisin-rel"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43806:SF11">
        <property type="entry name" value="CEREVISIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43806">
        <property type="entry name" value="PEPTIDASE S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00082">
        <property type="entry name" value="Peptidase_S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00723">
        <property type="entry name" value="SUBTILISIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52743">
        <property type="entry name" value="Subtilisin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51892">
        <property type="entry name" value="SUBTILASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00136">
        <property type="entry name" value="SUBTILASE_ASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00138">
        <property type="entry name" value="SUBTILASE_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 6" id="KW-0645">Protease</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6" id="KW-0720">Serine protease</keyword>
    <feature type="domain" description="Peptidase S8/S53" evidence="7">
        <location>
            <begin position="244"/>
            <end position="413"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003355"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OBZ86274.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="449" mass="47388" checksum="4861C6E196450E91" modified="2016-11-30" version="1">MSAVSAAAIGSDIEAAINSSTGNGQFIIELNKNACINDFVPKFIDHAYEITAQTANKDLAKKSNKVVRRDTEEEHVHVFDAYNIGDDYKAIGVKFKDSSIIRDLVKKLGNEIVTIIPDQDLQFDLPTLKTPAAKEGHSRRAPSERKGNLHIESLGKGCAKGDNNVYMKRAEIAPEPVFSAQSTISQPNADWGLVRITQRGPVGSATTYRYSTTAGSSVIAYVIDDGLRADHQEFEGRATFGGKTYGVAKKIKLVGVKALDSGGIGQISAILSSLQFVSTNAGSHLGKAIVNMSFGIEKTRIPSSGLASLNSAINSLVASGVPVFTAVGNANKDACNFMPAGNTRTYSVGATTKDDKMAGFSNYGRCTRILAPGENIKSAISTSTTATAVMSGTSMAAPHVAGVAALFIDLLGKPKPIAVYNTLDAAVTKNAIHNVKSGTPNAFLFINPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NFZ9</accession>
    <name>A0A1C7NFZ9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">CCT-theta</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">cct8</name>
        <name evidence="11" type="ORF">A0J61_03927</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Molecular chaperone; assists the folding of proteins upon ATP hydrolysis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Component of the T-complex protein 1 (TCP1) complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the TCP-1 chaperonin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000181">
        <property type="protein sequence ID" value="OBZ88022.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NFZ9"/>
    <dbReference type="FunCoup" id="A0A1C7NFZ9">
        <property type="interactions" value="822"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NFZ9"/>
    <dbReference type="InParanoid" id="A0A1C7NFZ9"/>
    <dbReference type="OrthoDB" id="1748577at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005832">
        <property type="term" value="C:chaperonin-containing T-complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd03341">
        <property type="entry name" value="TCP1_theta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.50.7.10:FF:000008">
        <property type="entry name" value="T-complex protein 1 subunit theta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.7.10">
        <property type="entry name" value="GroEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.560.10">
        <property type="entry name" value="GroEL-like equatorial domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.260.10">
        <property type="entry name" value="TCP-1-like chaperonin intermediate domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012721">
        <property type="entry name" value="Chap_CCT_theta"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017998">
        <property type="entry name" value="Chaperone_TCP-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002194">
        <property type="entry name" value="Chaperonin_TCP-1_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002423">
        <property type="entry name" value="Cpn60/GroEL/TCP-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027409">
        <property type="entry name" value="GroEL-like_apical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027413">
        <property type="entry name" value="GROEL-like_equatorial_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027410">
        <property type="entry name" value="TCP-1-like_intermed_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02346">
        <property type="entry name" value="chap_CCT_theta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11353">
        <property type="entry name" value="CHAPERONIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00118">
        <property type="entry name" value="Cpn60_TCP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00304">
        <property type="entry name" value="TCOMPLEXTCP1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52029">
        <property type="entry name" value="GroEL apical domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48592">
        <property type="entry name" value="GroEL equatorial domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54849">
        <property type="entry name" value="GroEL-intermediate domain like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00750">
        <property type="entry name" value="TCP1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00751">
        <property type="entry name" value="TCP1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8 10" id="KW-0143">Chaperone</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011381"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00029602"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU004187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="OBZ88022.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="550" mass="60397" checksum="5782D4765C0E54D4" modified="2016-11-30" version="1">MALRVPKSTLPQLFKDGYKFQQGVEEAVLRNIDATHELSEVVRTSMGPNGRNKMIINHLEKLFVTNDAATIIRELDVVHPAAKLLVMASQQQENELGDNTNLVLVFAGELLQKAADLLKLGLHPSEVVQGYELARDRALSILEELSVDKVESLTDRAELNKLIRATISSKQYGYEDFLGDLVCEAALNIMPKNVKDFNIDNVRVVKVMGSSIHESRVVRGMVFGREPEGIVQKATQAKVAVFTCPLDISQTETKGTVLIHNAQEMLNFSKDEEKQMEKIFQDLAEAGVKVVVTGNGIGELCLHYLNRYNIMAVKVLSKFDLRRLCRVIGATALARLGTPMAEEMGHCDIVETVEIGSDRVTVFRQEEAEKSRTTTIVIRGATQNHMDDIERAIDDGVNAIKAATRNPSLLAGAGAVEMELNKRLQSVASKTPGLNQHAIKKFAEALEVIPRTLCENAGMDATAVLSRLYAAHYQEGDVGAHVGVDVENENDGTLDTTKAVIFDSLVSKYSAYKLAADAAITILRVDQIIMSKPAGGPKPLKKDGHWDEDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NGL2</accession>
    <name>A0A1C7NGL2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">T-lymphoma invasion and metastasis-inducing protein 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">Tiam2</name>
        <name evidence="3" type="ORF">A0J61_04060</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000190">
        <property type="protein sequence ID" value="OBZ87889.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NGL2"/>
    <dbReference type="STRING" id="101091.A0A1C7NGL2"/>
    <dbReference type="InParanoid" id="A0A1C7NGL2"/>
    <dbReference type="OrthoDB" id="660555at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005085">
        <property type="term" value="F:guanyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00160">
        <property type="entry name" value="RhoGEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.900.10">
        <property type="entry name" value="Dbl homology (DH) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035899">
        <property type="entry name" value="DBL_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000219">
        <property type="entry name" value="DH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051092">
        <property type="entry name" value="FYVE_RhoGEF_PH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12673">
        <property type="entry name" value="FACIOGENITAL DYSPLASIA PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12673:SF159">
        <property type="entry name" value="LD03170P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00621">
        <property type="entry name" value="RhoGEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00325">
        <property type="entry name" value="RhoGEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48065">
        <property type="entry name" value="DBL homology domain (DH-domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50010">
        <property type="entry name" value="DH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DH" evidence="2">
        <location>
            <begin position="194"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="96"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="102"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ87889.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="389" mass="45388" checksum="EA325B9B0470D159" modified="2016-11-30" version="1" fragment="single">NSDPDNNKIIDTQHIMPPLTYPITFEEIEAKAWASHTVSDILTDVTPVSFEPYVSERVPVEDPSVQTITNDLKRSFSFLESGLFRHYYREKEVRNSRRSQSTIIPPTHPTNTPIHRLFPRPSISGRIRQRMDRFGSVKQQLSNTSDLFHDFYSHHKPSAKEQKGIALWKETYAAYLAKSSLDLTFVQSKRSVQLSKFIMNELLTTEETYLNHLLIVQHYYQNPLLEAASAKKKPLVNLRDVEIIFAYIPQLINLSTTLVERLRNTIENYLDYDENRNQIAIGKTFCDLEKYFDIYIYYAANFLKSKKHLAKASSSIIYRQLVQDSMQQKKTNRLLLSDYMIAPIQRITRYCLLLKDLRKHLDHSFEDYVYINRALNCLSALAYAMNAIQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NH15</accession>
    <name>A0A1C7NH15_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">PAN2-PAN3 deadenylation complex catalytic subunit PAN2</fullName>
            <ecNumber evidence="9">3.1.13.4</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">PAB1P-dependent poly(A)-specific ribonuclease</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">Poly(A)-nuclease deadenylation complex subunit 2</fullName>
            <shortName evidence="9">PAN deadenylation complex subunit 2</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="primary">pan2</name>
        <name evidence="9" type="synonym">PAN2</name>
        <name evidence="12" type="ORF">A0J61_03662</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Catalytic subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein PAB1. PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent mRNA decaping and subsequent 5'-3' exonucleolytic degradation by XRN1. May also be involved in post-transcriptional maturation of mRNA poly(A) tails.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>Exonucleolytic cleavage of poly(A) to 5'-AMP.</text>
            <dbReference type="EC" id="3.1.13.4"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="9">
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </cofactor>
        <text evidence="9">Binds 2 metal cations per subunit in the catalytic exonuclease domain.</text>
    </comment>
    <comment type="activity regulation">
        <text evidence="9">Positively regulated by the regulatory subunit PAN3.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Forms a heterotrimer with an asymmetric homodimer of the regulatory subunit PAN3 to form the poly(A)-nuclease (PAN) deadenylation complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="9">Contains a pseudo-UCH domain. This ubiquitin C-terminal hydrolase (UCH)-like or ubiquitin specific protease (USP)-like domain is predicted to be catalytically inactive because it lacks the active site catalytic triad characteristic of thiol proteases, with residues at the equivalent structural positions that are incompatible with catalysis, and it cannot bind ubiquitin. It functions as a structural scaffold for intra- and intermolecular interactions in the complex.</text>
    </comment>
    <comment type="domain">
        <text evidence="9">The linker, or PAN3 interaction domain (PID), between the WD40 repeats and the pseudo-UCH domain mediates interaction with PAN3.</text>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the peptidase C19 family. PAN2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.13.4" evidence="9"/>
    <dbReference type="EMBL" id="LUGH01000162">
        <property type="protein sequence ID" value="OBZ88280.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NH15"/>
    <dbReference type="FunCoup" id="A0A1C7NH15">
        <property type="interactions" value="471"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NH15"/>
    <dbReference type="InParanoid" id="A0A1C7NH15"/>
    <dbReference type="OrthoDB" id="16516at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000932">
        <property type="term" value="C:P-body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031251">
        <property type="term" value="C:PAN complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004535">
        <property type="term" value="F:poly(A)-specific ribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000289">
        <property type="term" value="P:nuclear-transcribed mRNA poly(A) tail shortening"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd06143">
        <property type="entry name" value="PAN2_exo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.10:FF:000028">
        <property type="entry name" value="PAN2-PAN3 deadenylation complex catalytic subunit PAN2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.70.10">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03182">
        <property type="entry name" value="PAN2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030843">
        <property type="entry name" value="PAN2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050785">
        <property type="entry name" value="PAN2-PAN3_catalytic_subunit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048841">
        <property type="entry name" value="PAN2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028881">
        <property type="entry name" value="PAN2_UCH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013520">
        <property type="entry name" value="Ribonucl_H"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028889">
        <property type="entry name" value="USP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15728">
        <property type="entry name" value="DEADENYLATION COMPLEX CATALYTIC SUBUNIT PAN2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15728:SF0">
        <property type="entry name" value="PAN2-PAN3 DEADENYLATION COMPLEX CATALYTIC SUBUNIT PAN2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20770">
        <property type="entry name" value="PAN2_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00929">
        <property type="entry name" value="RNase_T"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13423">
        <property type="entry name" value="UCH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00479">
        <property type="entry name" value="EXOIII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50235">
        <property type="entry name" value="USP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8 9" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="7 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 9" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="5 9" id="KW-0540">Nuclease</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="USP" evidence="11">
        <location>
            <begin position="492"/>
            <end position="879"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="741"/>
            <end position="766"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="741"/>
            <end position="753"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="933"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="935"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="1043"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="1096"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03182"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="OBZ88280.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="1163" mass="131345" checksum="20A4F250AF064D33" modified="2016-11-30" version="1">MDSSWNEVQHICDPNLNKVTPVSAVCWDPYHELLWTGNDTGRVCSYYGKGLQRYTSWKAHKDEQVRQIRVLDRGVISLSPKSLQMRDRRGLVKWSVSNEDTKDLHCMTSTTLTNGELLVAGQQDDMLVISLARGTVTRKISGASNIVVLKSLPRSICAGSLLGEVTLRDPRTMKIEQRVQAHTATLSDLDVSGNLLLTCGFSQRQGSLIMDPLVKVYDIRMAVRTLAPIPFPSGPMFLKMHPTLSTTCLVASQTGQFQLCDVSSLIMGSYAAPAQFHQIQTSSYITAMDISSSAQSLVFADGASFVYQYADREDFDINPYSLPLTTPDIVQPITTTMKEDSPLSSVGMPYYTDPLLSVWPANKVYEVGAQPTPIDEEIIRNMKTIDFVGYAPNPGNIHRNQQPRKKKILTKKNGPKFRSEQERELLQARKVLVGDDGLIRHSGRRSSSVGDIHTLDPTVVNMPRYYQRVEIQYSRFGVDDFDFGYFNATQYGGLETHIRNSYCNSLLQVLYFISPLRKIAKSHIKTACPKDNCLLCELGFLFRMLEDSKGQNCQATNFLRAFSTIPQAFALGLFEPDTPDRNLSYSTLMQNFTRFIMEQIHQEANTLSNPLISKTWTQHVPLQEEQQQQLEVPSTMQQLFGLQTLSQSKCGSCQQEVSRITYPFVVDMLYPKKNDRKSRKRSFTSILKASMYRENQTKAWCSHCHQYQPTTTKKMICGLPGVMLINSSAASSEEALIWRQNGPNNNKQFTSQDPPADHEEGESQPTLSSWLPERFGIYMNGSELVIKALPVDKEIPPEFKGSPETCAIYELSSTILQVQAEEEATHLVSQIRVTETEEDVKSSAWYLFNDFLVRKIRAEEVFSFKGTWKTPAVLQYTRIDLDDLLDLEVLPSQVDYSLLFENLSIAKEPNLNPRHQVLSKEEMPKPGTLVAIDAEFVALQQEETEIRSDGTKSLIRPSTLTLARVSVLRGDTGPQEGVPFIDDYITTKEPIVDYLTEFSGIRPGDLDQAQSKHTLVPLKVAYKKLRLLVDLGCIFIGHGLNKDFRIINLLVPSEQIIDTVDIYHIRNRQRKISLRFLAWHLLNQDIQSETHDSIEDAKTALVLYKKYLDYKQNGTFGQVLEEVYQAGHKANWLKGPKDALSRVSSAPQIENLASPTSLSLYFR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NH53</accession>
    <name>A0A1C7NH53_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Leucine-rich repeat-containing protein 40</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">LRRC40</name>
        <name evidence="4" type="ORF">A0J61_03871</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000176">
        <property type="protein sequence ID" value="OBZ88079.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NH53"/>
    <dbReference type="STRING" id="101091.A0A1C7NH53"/>
    <dbReference type="InParanoid" id="A0A1C7NH53"/>
    <dbReference type="OrthoDB" id="660555at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003591">
        <property type="entry name" value="Leu-rich_rpt_typical-subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050216">
        <property type="entry name" value="LRR_domain-containing"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48051">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48051:SF46">
        <property type="entry name" value="LEUCINE RICH REPEAT-CONTAINING DOMAIN PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00560">
        <property type="entry name" value="LRR_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13516">
        <property type="entry name" value="LRR_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13855">
        <property type="entry name" value="LRR_8"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00019">
        <property type="entry name" value="LEURICHRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00364">
        <property type="entry name" value="LRR_BAC"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="SMART" id="SM00368">
        <property type="entry name" value="LRR_RI"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SMART" id="SM00365">
        <property type="entry name" value="LRR_SD22"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SMART" id="SM00369">
        <property type="entry name" value="LRR_TYP"/>
        <property type="match status" value="11"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="22"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="71"/>
            <end position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OBZ88079.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="699" mass="78232" checksum="D34B82635C25E61C" modified="2016-11-30" version="1">MSSNTRKPIQPRPTKASMLRLQKQQDTGPAASQSKPVKTESKPSTSRTKSTVSASDGVKAFMAQQRARMGTKIEKTEEKPKQKKGNFMTGAERYGGGEVQDDKPRMNTRSIQVIIKQAKSLGKLDISSRGLEQIPDEVLNMYHVDPKSIVIDFSSSGDAWYDNVELTQFIAGDNNLTEVDARLGEEFGALKKLDLRDNRLKHLPSNLYLLQNLTSIFLPYNSFESMPTVLSELKQLRELDLSHNQLKGAITVRSNTIEVLDLSYNDISSIDFTGDSNLIKLNLSHNELEELPCAFRNWIRLQELNVSQNRLMYLFPAAIGHDQATATLNSLIRLNAGNNSILSLVEGDSTKVILPKLVELVLSTNKLSEAGLAALIHTPQLQTLDISSNQLKDIPKSVMELTQLVRLDVRGNQLRTLSYELGKLDQLKMIYCEGNPMRSFTSMSPTQLIESLKSNYNQQQLQEQEDQQPEDTSIAAGHDALEILSQQLERKVNLTQRLDLSNRKLTELPKQELQFQHDIPGTILLDHNELTLFPHSLCGLSNFIVTLVLDHNRLSNFSLSIEGVVFHQLKTLKLNNNRIKTLECSHHVSFPKLEELSLNHNALTTLSNAMADALPSLRVFSASSNKLDKLTEKPFGPKLEVIDLSNNDISALPSGLSTLSSLRELIVFGNRFRVPRPAIVDQGTGAVLEFLRRRHNTFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NHG3</accession>
    <name>A0A1C7NHG3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">GTPase-activating protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">gap1_2</name>
        <name evidence="3" type="ORF">A0J61_03957</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000183">
        <property type="protein sequence ID" value="OBZ87986.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NHG3"/>
    <dbReference type="FunCoup" id="A0A1C7NHG3">
        <property type="interactions" value="4"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NHG3"/>
    <dbReference type="InParanoid" id="A0A1C7NHG3"/>
    <dbReference type="OrthoDB" id="775356at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005938">
        <property type="term" value="C:cell cortex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046580">
        <property type="term" value="P:negative regulation of Ras protein signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05132">
        <property type="entry name" value="RasGAP_GAPA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.506.10">
        <property type="entry name" value="GTPase Activation - p120gap, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000593">
        <property type="entry name" value="RasGAP_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023152">
        <property type="entry name" value="RasGAP_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001936">
        <property type="entry name" value="RasGAP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008936">
        <property type="entry name" value="Rho_GTPase_activation_prot"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14149:SF17">
        <property type="entry name" value="GTPASE-ACTIVATING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14149">
        <property type="entry name" value="RAS GTPASE-ACTIVATING PROTEIN WITH IQ MOTIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00616">
        <property type="entry name" value="RasGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03836">
        <property type="entry name" value="RasGAP_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00323">
        <property type="entry name" value="RasGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48350">
        <property type="entry name" value="GTPase activation domain, GAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143885">
        <property type="entry name" value="RGC domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00509">
        <property type="entry name" value="RAS_GTPASE_ACTIV_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50018">
        <property type="entry name" value="RAS_GTPASE_ACTIV_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ras-GAP" evidence="2">
        <location>
            <begin position="190"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="63"/>
            <end position="90"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50018"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ87986.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="802" mass="90778" checksum="90585763DADD9A1D" modified="2016-11-30" version="1">MTDRKSGMVQAYGYPGGTGANPIVSRAVAAAAANSHHSSRGKSGRGSKRYSVSAFYSMAAEQDNEVEDELAQAQRSLRELKAKISAQSKKNFVLERDVRYLDSRIALLIQNRIALAEQNEMASHLEEHGISESDSFPDDRKMQLYGNLFYILQSEPRHIATLCRLVSLAEIDSLLQTVMFTLYGNQYESREEHLLLTMFQNVLAAQFETSTEFGSLLRANTPVSRMMTTYTRRGPGQSYLKSILSDKIKNLVQEHDHNLEINPLKVYEQMVSQVESEKGYLPPDMPKSVTPEIAASNPTVQNIIAPRLKKLIDIAESFLDTILSSTASVPYGIRWICKQIRSLTRRKSPDASEYSVCSMIGGFFFLRFINPAIVTPRAYMLLDSVPGNAPRRTLTLIAKMLQNLANRPSYAKEAYMLPTNPFVERNKQRINRFLNELCEVTDFYETLEMDQYMALSKKDIIINITLNEMYVTHALIHRHLDTIAPKEKDHLRILINDLSPTPAQVSRKENKAVELPLFSRWEIPIQDLTTALMSENNITQNDILYMETKAIYVQLIRSLPHLASSTQIDLDYIAETAATTKDAQLVRKGIKVKDMLRELEDAGVIDHRDHYKLLVEEITQELAHLGSLKEKVLQESESLEGVFRSILDHNSYLKSQLESYKAYLQNVRIQSGGDKTSKNSVGIGVEIEGGARPKKTAKAAPKGPFKFSHNHLEKDGIISESTVPENRRTNIFFSITSPLPGTFIIAMHFKGRDKPILEMDLKLDDLLEKQQDNIELLDLEYVRLNVAKTLALLNKIFITRSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NHX7</accession>
    <name>A0A1C7NHX7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Rho GTPase-activating protein 23</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">ARHGAP23_0</name>
        <name evidence="9" type="ORF">A0J61_03224</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000135">
        <property type="protein sequence ID" value="OBZ88727.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NHX7"/>
    <dbReference type="STRING" id="101091.A0A1C7NHX7"/>
    <dbReference type="InParanoid" id="A0A1C7NHX7"/>
    <dbReference type="OrthoDB" id="79452at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00159">
        <property type="entry name" value="RhoGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00174">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00201">
        <property type="entry name" value="WW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.70.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.555.10">
        <property type="entry name" value="Rho GTPase activation protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.40">
        <property type="entry name" value="SH3 Domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001849">
        <property type="entry name" value="PH_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050729">
        <property type="entry name" value="Rho-GAP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008936">
        <property type="entry name" value="Rho_GTPase_activation_prot"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000198">
        <property type="entry name" value="RhoGAP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036028">
        <property type="entry name" value="SH3-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001452">
        <property type="entry name" value="SH3_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001202">
        <property type="entry name" value="WW_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036020">
        <property type="entry name" value="WW_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23176:SF129">
        <property type="entry name" value="RHO GTPASE ACTIVATING PROTEIN AT 16F, ISOFORM E-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23176">
        <property type="entry name" value="RHO/RAC/CDC GTPASE-ACTIVATING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00169">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00620">
        <property type="entry name" value="RhoGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00018">
        <property type="entry name" value="SH3_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00397">
        <property type="entry name" value="WW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00452">
        <property type="entry name" value="SH3DOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00233">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00324">
        <property type="entry name" value="RhoGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00326">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00456">
        <property type="entry name" value="WW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48350">
        <property type="entry name" value="GTPase activation domain, GAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50044">
        <property type="entry name" value="SH3-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51045">
        <property type="entry name" value="WW domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50003">
        <property type="entry name" value="PH_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50238">
        <property type="entry name" value="RHOGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50002">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01159">
        <property type="entry name" value="WW_DOMAIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50020">
        <property type="entry name" value="WW_DOMAIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0343">GTPase activation</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 3" id="KW-0728">SH3 domain</keyword>
    <feature type="domain" description="SH3" evidence="5">
        <location>
            <begin position="1"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="domain" description="WW" evidence="7">
        <location>
            <begin position="126"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="domain" description="PH" evidence="6">
        <location>
            <begin position="209"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="domain" description="Rho-GAP" evidence="8">
        <location>
            <begin position="397"/>
            <end position="581"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="151"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="366"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="367"/>
            <end position="390"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022468"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50238"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OBZ88727.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="589" mass="67383" checksum="D3A342E6F86E2B2B" modified="2016-11-30" version="1">MSLIALWDYTAEGELELSFKQGDKVKLLEKHNDDWWEGSLNESCRSVAKGQLGNEIGFFPANRVKLESVEDQDNTVADSTLPQKIPLEHHDSIKSDTDIIIAKEEEVVKDHPLCTVASAPAIMDKLSLPNGWQEAYAPDGSIYYFNENTRQTTWDRPTEDETAEDQLSPSPSSPPPLPPRNNVDLDEMIEGLTAEDLSKLEVDRLQKEWIRHQGYVEMKMISEKDAGSKLSSWKAYYAVLSNGFLLLYKESHAKNKKSSKSRVPVGSFDLDSCKIDPAGKQDTKRKHVFIISTPRKVKLYVQTTNNSEFSAWLDAIMRELIARKEGQNEDSDILRLLKSLSIDESQMKVNRKMIQEDESRKKYWFSPKQQGKNGDYSETMTSPKQTSASGENVVFGGELRMEENGDIPHVVSLCIQQVEERGLQSVGIYRLSGPASSIQKYKTMFNQGEHVSLKEEHDINAVTGLLKLYFRELRNPLMTYEYYEWFIDAARIADYEERMYQIKSVIHSLPKPNFTVLEYLMRHLNRVASFSEINKMEPSNLALIFSVGLLRAPQEDLSSIMMSDLQSRVVEAIIQQVDWFFEDEDNTRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-06-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NJ09</accession>
    <name>A0A1C7NJ09_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_02862</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000114">
        <property type="protein sequence ID" value="OBZ89081.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NJ09"/>
    <dbReference type="InParanoid" id="A0A1C7NJ09"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="126"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ89081.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="126" mass="14324" checksum="AE12ECD2D6E85711" modified="2016-11-30" version="1" fragment="single">YQNCLDVTAIHSSVNKKLFFISEKAEVKLLVKAEPNTAKAAFSKSTYEGHRYNCFCCREQLWSRITGKPSSTHSDEFNDFVDYLVAHIIYDSSRSLSQTAKEKLEQAVYYLLKLPSPPLVSLPQPC</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NJ34</accession>
    <name>A0A1C7NJ34_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Velvet domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">A0J61_02938</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000118">
        <property type="protein sequence ID" value="OBZ89020.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NJ34"/>
    <dbReference type="STRING" id="101091.A0A1C7NJ34"/>
    <dbReference type="InParanoid" id="A0A1C7NJ34"/>
    <dbReference type="OrthoDB" id="5599552at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.3960">
        <property type="entry name" value="Velvet domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021740">
        <property type="entry name" value="Velvet"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037525">
        <property type="entry name" value="Velvet_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038491">
        <property type="entry name" value="Velvet_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33572">
        <property type="entry name" value="SPORE DEVELOPMENT REGULATOR VOSA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33572:SF18">
        <property type="entry name" value="SPORE DEVELOPMENT REGULATOR VOSA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11754">
        <property type="entry name" value="Velvet"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51821">
        <property type="entry name" value="VELVET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Velvet" evidence="6">
        <location>
            <begin position="19"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="193"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="252"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="201"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="261"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="283"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="320"/>
            <end position="343"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51821"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OBZ89020.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="470" mass="53493" checksum="6363CF9C706DD8C5" modified="2016-11-30" version="1">MSSNGCTYRFIESTLSGSTDQIIYDIEIRQQPQRAKVSLINERDRRSIEPPPILQLHWRNCSEDELKKSLQSPFYFIVANLVTEDDTETPLVPVQNYLSGTTVSSLYRLRDIDNSDGGFFVFGDLAVKREGKFKLRFSLFEIVEGQVKNRKTILSNTFTVYIPKQFPGPVEATFLSRTFSDQGVKMRIRKEHRLQSRKRKSDAATKEVAEHKRVTRKYHSKHIDMMVASSSHLEPVNNSNSDVFFGKWQVASRTPHPRPSTPLLLPSTPNNTNHSDDHLQSFPSPESTVYSSTSSGWHHQQQQQQEPVHQQESAIYRSEPSYRSEHTVVHRQEPTVHHSEPVHRPIPMRETAYRPSSSPHVASIPPQYRSSIASPPFKSIASPSNSSLAQYHTCHDSPSQPLSAVKRLPTPPSCFSEIPREKHWGTTLPPLRAIMNSTDPFHSETSSLFPLLLPPPSTRIVANKPFFPHY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NJF9</accession>
    <name>A0A1C7NJF9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Transforming growth factor beta regulator 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">TBRG1_0</name>
        <name evidence="4" type="ORF">A0J61_02720</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000106">
        <property type="protein sequence ID" value="OBZ89243.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NJF9"/>
    <dbReference type="STRING" id="101091.A0A1C7NJF9"/>
    <dbReference type="InParanoid" id="A0A1C7NJF9"/>
    <dbReference type="OrthoDB" id="285793at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051726">
        <property type="term" value="P:regulation of cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.360">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003889">
        <property type="entry name" value="FYrich_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003888">
        <property type="entry name" value="FYrich_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040092">
        <property type="entry name" value="TBRG1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22715">
        <property type="entry name" value="TRANSFORMING GROWTH FACTOR BETA REGULATED GENE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22715:SF0">
        <property type="entry name" value="TRANSFORMING GROWTH FACTOR BETA REGULATOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05965">
        <property type="entry name" value="FYRC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05964">
        <property type="entry name" value="FYRN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00542">
        <property type="entry name" value="FYRC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00541">
        <property type="entry name" value="FYRN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51543">
        <property type="entry name" value="FYRC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51542">
        <property type="entry name" value="FYRN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="55"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="55"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="72"/>
            <end position="96"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OBZ89243.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="262" mass="30555" checksum="567DD0C292453A70" modified="2016-11-30" version="1">MVQKGVDVGCQTDPWEDTHMEKYRKMKRKLVEFIAKQKEAKVALDKANQKIQHLLEKKRSQKTEWHDPMDVSIEEEEEEVVEGEYASDLEEDELEETPPPKKMRVVRKRQVIIPRDRDGQIRLPFQIASLNIISLGQVEYDRPNFHNERYIFPIGYTAERTYMSMVEPNNQTIYTCRVEDGGDGPLFTLQAADCPDEKISARTATRVWGSVLRKANEVRQKETSNAISGPEYYGFSHPLVIKMIEEMEGVDKCVRYIRRSRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NJK4</accession>
    <name>A0A1C7NJK4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">alpha-galactosidase</fullName>
            <ecNumber evidence="3">3.2.1.22</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">aglD</name>
        <name evidence="8" type="ORF">A0J61_02639</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 10">
            <text>Hydrolysis of terminal, non-reducing alpha-D-galactose residues in alpha-D-galactosides, including galactose oligosaccharides, galactomannans and galactolipids.</text>
            <dbReference type="EC" id="3.2.1.22"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the glycosyl hydrolase 27 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.22" evidence="3"/>
    <dbReference type="EMBL" id="LUGH01000102">
        <property type="protein sequence ID" value="OBZ89307.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NJK4"/>
    <dbReference type="FunCoup" id="A0A1C7NJK4">
        <property type="interactions" value="181"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NJK4"/>
    <dbReference type="InParanoid" id="A0A1C7NJK4"/>
    <dbReference type="OrthoDB" id="5795902at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004557">
        <property type="term" value="F:alpha-galactosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd14792">
        <property type="entry name" value="GH27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1180">
        <property type="entry name" value="Golgi alpha-mannosidase II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002241">
        <property type="entry name" value="Glyco_hydro_27"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013780">
        <property type="entry name" value="Glyco_hydro_b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041233">
        <property type="entry name" value="Melibiase_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11452:SF75">
        <property type="entry name" value="ALPHA-GALACTOSIDASE MEL1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11452">
        <property type="entry name" value="ALPHA-GALACTOSIDASE/ALPHA-N-ACETYLGALACTOSAMINIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16499">
        <property type="entry name" value="Melibiase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17801">
        <property type="entry name" value="Melibiase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51011">
        <property type="entry name" value="Glycosyl hydrolase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="domain" description="Alpha galactosidase C-terminal" evidence="7">
        <location>
            <begin position="374"/>
            <end position="448"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009743"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF17801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OBZ89307.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="454" mass="51904" checksum="699A4DA317CDD667" modified="2016-11-30" version="1">MLEQKKDLDSRVSKPKLVPEFAKKPLLGFSTWSLQLLDDVPGYGGKHTNPWFNEDNIKEISDTMKAKMPNYEYINLDSGWCSECDEFGRWSVNKEIFPNGLRPVSDYLKKNGHKLGVYILPGIRQDGVTQKKRIKGTEYTLDQLTPSRREGCGFKGTTFMPDEHNELVQAYYDSIADLFHEWGVSFVKLDAVGPGGGSEYYPCTSPDNRACTQMMYHAFRRYDIWLEISWQLDVGYADEWAHISNGARIYVDIESYSTKTMTSSHRVMQRITPCEKWAEKHVVGSEYGFYIDLDAVLVGMTVDGKCVDGLDNDDVRQTYISFWAIVSSVFYTGADPRRIPDKYLSWYNHPEILEIHQSGVMAKPIGSGNVWQNRKQVWWKQLKDGRIYVCLLNAHTYIFMLGLSHEVTLDLAAIGLQRAKLKDVWTGEQLGIYDNKYSIVLRAGQSQTLLVTPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NJT2</accession>
    <name>A0A1C7NJT2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Ubiquitin carboxyl-terminal hydrolase</fullName>
            <ecNumber evidence="8">3.4.19.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">UCHL5_0</name>
        <name evidence="11" type="ORF">A0J61_02574</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).</text>
            <dbReference type="EC" id="3.4.19.12"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 7 8">Belongs to the peptidase C12 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.19.12" evidence="8"/>
    <dbReference type="EMBL" id="LUGH01000098">
        <property type="protein sequence ID" value="OBZ89377.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NJT2"/>
    <dbReference type="STRING" id="101091.A0A1C7NJT2"/>
    <dbReference type="InParanoid" id="A0A1C7NJT2"/>
    <dbReference type="OrthoDB" id="1924260at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004843">
        <property type="term" value="F:cysteine-type deubiquitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016579">
        <property type="term" value="P:protein deubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006511">
        <property type="term" value="P:ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.532.10">
        <property type="entry name" value="Peptidase C12, ubiquitin carboxyl-terminal hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001578">
        <property type="entry name" value="Peptidase_C12_UCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036959">
        <property type="entry name" value="Peptidase_C12_UCH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10589">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10589:SF16">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE ISOZYME L5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01088">
        <property type="entry name" value="Peptidase_C12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00707">
        <property type="entry name" value="UBCTHYDRLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52048">
        <property type="entry name" value="UCH_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5 7 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 7 8" id="KW-0645">Protease</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 7 8" id="KW-0788">Thiol protease</keyword>
    <keyword evidence="4 7 8" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="UCH catalytic" evidence="10">
        <location>
            <begin position="15"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="9">
        <location>
            <begin position="307"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="7">
        <location>
            <position position="96"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="7">
        <location>
            <position position="179"/>
        </location>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="7">
        <location>
            <position position="90"/>
        </location>
    </feature>
    <feature type="site" description="Important for enzyme activity" evidence="7">
        <location>
            <position position="194"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01393"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU361215"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS52048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="OBZ89377.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="381" mass="43366" checksum="2824589A46A6846C" modified="2016-11-30" version="1">MTTSELTEKAESNEKWGLIPSDPAVFDDMIQQYGVKDTIVQEVLTLDFEDLEKNGPVHGLIFISRYVEEELPSDFEKIDPDAEKVVFTAQVVTNVCGTLALLAVLFNADIERGEILNNFLEFTKGFSPVNRGICLGNSSEIHKIHDAYAIHNSQLEIDDTLSDVSEDGNIEFIDVDDFHYITYIYKDGYLWELDGLKYQPVKVATCNKDNWLDAVKPILQKRMDSSAQNELTFSLMAVTQDMYPCLLRRKDAYDKCIALTNGAFNRVFAPSTISKKKKACHNLLTLVNSPDAALMSDIWNSLQSGNTEFAKIKLEDFKQQAEALNNQLQLVKEQRDTARIDAERQKFDYTPFINSLLTKAYYHQLLEDNSRPKKRSRLSKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NJU1</accession>
    <name>A0A1C7NJU1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_04401</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000214">
        <property type="protein sequence ID" value="OBZ87554.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="InParanoid" id="A0A1C7NJU1"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ87554.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="95" mass="9876" checksum="D10F99A06A138362" modified="2016-11-30" version="1">MPAKDTAPPSSPRIDTTQASPGPEPSIAVLSHNLLSKYVSATGPQIETLKSPAAPLQQDVEDCAINDDDIPDLDSLLXTGGFPASQATAARHLMT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NKD6</accession>
    <name>A0A1C7NKD6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_02421</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000091">
        <property type="protein sequence ID" value="OBZ89525.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NKD6"/>
    <dbReference type="STRING" id="101091.A0A1C7NKD6"/>
    <dbReference type="InParanoid" id="A0A1C7NKD6"/>
    <dbReference type="OrthoDB" id="2258573at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.20">
        <property type="entry name" value="Apolipoprotein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="106"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="287"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="516"/>
            <end position="551"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="114"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="142"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="170"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="292"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="307"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="334"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="396"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="431"/>
            <end position="444"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ89525.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="551" mass="61625" checksum="978DDCB38231298A" modified="2016-11-30" version="1">MYRIPLQRARFTAATPMLRRPINARRTMATQSGEGRTGPSKTFIVALLAAAGGLAYYQRSKDEQKFYNGDSNTHETKQKITELGNRVIQDGQVREDLKDAKYHLKESANSTGDAARDAYGKVKEEGQEATEHLKSQANHVANKAEDKYKDAKEQFKDSKDQLKSEYNPMVKEKVYRSKTKSDDEAKLERYSEHGVRDTSALVGKDTDKVKPVWEDQAAKERSNVIVPHEEVSNNNHGGFFGGMFGSGKAGDATTNTKNNNNVVHNERMPTTIYDDAKYLAKDTKHEADHKISQLSRKASDTASDVSRQAEYEKDKMKHKLEEDKAKAGSLWQGLKEKAGMTAKSTEEEASRIKHDADRTIEEKTGQLQSGWNKVKGEAQSVVDGAQETASQTANRLKSETNKAASRADSETERLKRDAKGRLEEGKDYVNESMSQLSREASNQAEKVKQETEQTAKSWYAKGAEQVESGVSTVKEVADQDIQWAETKLQDAKQEVNRLLHPERTKEDGLVGHVKRGERYAEVEEGQLRPTRPNTDLKPADQVVEDASGNQI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NKP6</accession>
    <name>A0A1C7NKP6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">SUN-like protein 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">A0J61_04104</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="9">Interacts with EMP65.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Single-pass type I membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the SLP1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000193">
        <property type="protein sequence ID" value="OBZ87854.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NKP6"/>
    <dbReference type="FunCoup" id="A0A1C7NKP6">
        <property type="interactions" value="31"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NKP6"/>
    <dbReference type="InParanoid" id="A0A1C7NKP6"/>
    <dbReference type="OrthoDB" id="266334at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034975">
        <property type="term" value="P:protein folding in endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.120.260:FF:000099">
        <property type="entry name" value="Uncharacterized protein, isoform C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.260">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045120">
        <property type="entry name" value="Suco/Slp1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012919">
        <property type="entry name" value="SUN_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12953">
        <property type="entry name" value="MEMBRANE PROTEIN CH1 RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12953:SF0">
        <property type="entry name" value="SUN DOMAIN-CONTAINING OSSIFICATION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07738">
        <property type="entry name" value="Sad1_UNC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51469">
        <property type="entry name" value="SUN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="7" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="6 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 13" id="KW-0732">Signal</keyword>
    <keyword evidence="2 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 12" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="13">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008889754" description="SUN-like protein 1" evidence="13">
        <location>
            <begin position="23"/>
            <end position="837"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="672"/>
            <end position="697"/>
        </location>
    </feature>
    <feature type="domain" description="SUN" evidence="14">
        <location>
            <begin position="193"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="457"/>
            <end position="515"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="728"/>
            <end position="764"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="778"/>
            <end position="837"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="462"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="491"/>
            <end position="511"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="729"/>
            <end position="740"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="752"/>
            <end position="762"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004115"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00061226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00064635"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00075366"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51469"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="OBZ87854.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="837" mass="94789" checksum="DBE4E443D39C470F" modified="2016-11-30" version="1">MLCFLYLLQCVFCLLIPTLSSAKPTPKQCPHQPTYNIAFSKTCPAYAHDTVDFSAALFPDPSIISDISKPNYEEQRMTSTVTRTDPTSTHLTQPITRTQKEEGNQNRLVEDKRKPLVSFEEWQKKMLKLDDDSKDCRIKRKSGHLEQDSPGSKRQQVVDSIDGGFSDDFGSMLEDLIGGVVAKEKKPNVYAEGEYISPSQSGPENKDKKKQHFADARIKSLKERFNYASTDCAATVRKVNKQAKGAQSILYESKDQYLLNKCSADKFVIINLCEQIVVDTIVMANFEFFSSTFKDFRVYASSKYPTEDWRLLGQWQARNTRDLQVFKVPDSGFVEYVKIEFLTHYGHEYYCPLSLVRVHGMSMMEYYTTVESQDEGPAQLGEEHLWPAEVREQIIQPQFNITNTSESFPLKNEVEEEDVKSVIPPIHFVDQSAIPPVASNVPQHVIIETLVSVPTETEPLPSISVATSPSSSYSRSSSSSKVMVDVHQKASSHSSEETMPTSTSSASSNTTQPIHSSTPVLLIVNGTNSTNHTQESNAIQTATVTIHSTTSGIPKMSKDGGTQESIYKTIMKRLNILEVNMTLSQRFLDEQNKILNDVFLDMEKRHQEQLMMLIGHLNETASFKIESMKRRYEQWYEDLKEQTDSDMREMTTKISMLADQLSYERRMSVSQLIIMIILFVFMALSRGTFNILSPVVAAQQEQRNRRHIGREGLDAMLRQLRPIKKPVAPSTTLVDTTAKNESIVKKPKNPRRHSDSPYDSVRESTSNVIATKVVVAEEEELPEHSATSQNEALHTKLDQVYMQQEAREQTVPLIDIPEETSPFVIKNRKRSSTSPTY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NLA3</accession>
    <name>A0A1C7NLA3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">PRA1 family protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">Rabac1</name>
        <name evidence="6" type="ORF">A0J61_02674</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 5">Membrane</location>
            <topology evidence="1 5">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the PRA1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000104">
        <property type="protein sequence ID" value="OBZ89266.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NLA3"/>
    <dbReference type="FunCoup" id="A0A1C7NLA3">
        <property type="interactions" value="377"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NLA3"/>
    <dbReference type="InParanoid" id="A0A1C7NLA3"/>
    <dbReference type="OrthoDB" id="63113at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004895">
        <property type="entry name" value="Prenylated_rab_accept_PRA1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19317">
        <property type="entry name" value="PRENYLATED RAB ACCEPTOR 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19317:SF0">
        <property type="entry name" value="PRENYLATED RAB ACCEPTOR PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03208">
        <property type="entry name" value="PRA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="98"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="145"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="171"/>
            <end position="190"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU363107"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OBZ89266.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="203" mass="22594" checksum="1BE151A79951A60F" modified="2016-11-30" version="1">MATAATLLVSSVDSFINKSATTIIPDQLPPSPPTTTQGDAQVEGNRYLNYLKKFKQERLSDIRPLSDFFDRNRFKLTSSFELVSQRWSYNLQYFSSNYLLIMLCLAMYAVLTNWFLLFTMAFIYGGFHMILKLSQSGSLTIGGRVMSMPTVYTTYALGSFLLLLVSGATHTLFWIIGAGALIILCHAAVLEPGLEGDFADVQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NLB0</accession>
    <name>A0A1C7NLB0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Rho-GTPase-activating protein 5</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">rga5_3</name>
        <name evidence="3" type="ORF">A0J61_02092</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000075">
        <property type="protein sequence ID" value="OBZ89855.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NLB0"/>
    <dbReference type="FunCoup" id="A0A1C7NLB0">
        <property type="interactions" value="19"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NLB0"/>
    <dbReference type="InParanoid" id="A0A1C7NLB0"/>
    <dbReference type="OrthoDB" id="3196451at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005938">
        <property type="term" value="C:cell cortex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0060237">
        <property type="term" value="P:regulation of fungal-type cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.555.10">
        <property type="entry name" value="Rho GTPase activation protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008936">
        <property type="entry name" value="Rho_GTPase_activation_prot"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051025">
        <property type="entry name" value="RhoGAP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000198">
        <property type="entry name" value="RhoGAP_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15228:SF25">
        <property type="entry name" value="F-BAR DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15228">
        <property type="entry name" value="SPERMATHECAL PHYSIOLOGY VARIANT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00620">
        <property type="entry name" value="RhoGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00324">
        <property type="entry name" value="RhoGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48350">
        <property type="entry name" value="GTPase activation domain, GAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50238">
        <property type="entry name" value="RHOGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0343">GTPase activation</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rho-GAP" evidence="2">
        <location>
            <begin position="48"/>
            <end position="241"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022468"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50238"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ89855.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="292" mass="33644" checksum="A4044A6AB59F1A97" modified="2016-11-30" version="1">METSIETSPVRNWLKKMMASTKKHNPYDQPSLDVFGVPLVQSLQIANTPIAYESKEIVIGLIPIIVAKCGSFLKDQGLYVEGVFRKSGSARRIGELQQLFNSSSDHGIGFNWVGFNVHDAANCLRRFLNYLPEPVIPSSFYASFRNISTKSDTVDITMRVKEYQYLIDQLPKINQHLLFYLLDLLALFSRYEEYTKMNSVSLASVFTPGILLHPDHAMHPDQYKQSQKVVQFLIEYQDHFRLPKCQQSAPSKLNLYPTYHSREKQLLRANTVPVLKHRMEPNYELLQVIRNC</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NLB4</accession>
    <name>A0A1C7NLB4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_02005</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000071">
        <property type="protein sequence ID" value="OBZ89941.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NLB4"/>
    <dbReference type="InParanoid" id="A0A1C7NLB4"/>
    <dbReference type="OrthoDB" id="2354757at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009571">
        <property type="entry name" value="SUR7/Rim9-like_fungi"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06687">
        <property type="entry name" value="SUR7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="119"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="154"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="212"/>
            <end position="232"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ89941.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="253" mass="28066" checksum="C277103FCD089EA9" modified="2016-11-30" version="1">MLRTLQVIAIVLITASFILQMLTLLGNFRGLRSVYIARIILNYPSSSGSNIFDGFFGGLQNSVPNYFTLALFVVCQEINSDETICSPSSFGFRYGILQVLQNQIPSSLQTTISSVQKGVFIPSVVICFVLWCYAILCLFLLSRRDSRSIGCINRVLIILLALIAFLFCLATFVAQMIVYNLLQSGVQSLMTGSFGSLIDNLVVLTTERGRSIWLSLAAFIALFIAFILICITSCPCGRRRKRGTEDAYEMSRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NLU6</accession>
    <name>A0A1C7NLU6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Protein Zds1 C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_01842</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000063">
        <property type="protein sequence ID" value="OBZ90121.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NLU6"/>
    <dbReference type="STRING" id="101091.A0A1C7NLU6"/>
    <dbReference type="InParanoid" id="A0A1C7NLU6"/>
    <dbReference type="OrthoDB" id="5589766at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030010">
        <property type="term" value="P:establishment of cell polarity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010971">
        <property type="term" value="P:positive regulation of G2/M transition of mitotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040206">
        <property type="entry name" value="Zds1/2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013941">
        <property type="entry name" value="ZDS1_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28089">
        <property type="entry name" value="PROTEIN ZDS1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28089:SF1">
        <property type="entry name" value="PROTEIN ZDS1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08632">
        <property type="entry name" value="Zds_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01327">
        <property type="entry name" value="Zds_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Protein Zds1 C-terminal" evidence="2">
        <location>
            <begin position="296"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="75"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="123"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="161"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="129"/>
            <end position="143"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM01327"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ90121.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="367" mass="41947" checksum="BD0923E944B95D35" modified="2016-11-30" version="1">MLTEKASNNDMYAALMLSDLLNNEQHNVPPPLPPHEEPCLPVDDVIWQVVPADKHPQIAPNEFANFLRTHGANIPTRRSSSLRRRESILSQSISPRENEEDPQDSKPKRSLSEKKKAFLKRMQDNQLEDPLKDSQIFDKHSSAKDDSNVIVKTDKSLLRRSAFSARGRSRKSKEAQRRSLSHRRASSNGDARLNTWDKSVGISLYDQPVNLSEWIDLGSASLESNDSQRGMLSRVHDAESELLCPPKPIPKRTSWLAGLFKKESNSISGLTSLLQRSFSLKSPKETPKRASSRLEAPIEPFFNPYRFPLHVERAIYRLSHMKLADPRRPLRQQVLISNLMFWYIHSGNQGHPERNRQPVEKTQMAKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NM44</accession>
    <name>A0A1C7NM44_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Tubulin-specific chaperone A</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">TBCA</name>
        <name evidence="4" type="ORF">A0J61_01798</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="3">Supercomplex made of cofactors A to E. Cofactors A and D function by capturing and stabilizing tubulin in a quasi-native conformation. Cofactor E binds to the cofactor D-tubulin complex; interaction with cofactor C then causes the release of tubulin polypeptides that are committed to the native state.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
            <location evidence="3">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the TBCA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000061">
        <property type="protein sequence ID" value="OBZ90145.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NM44"/>
    <dbReference type="FunCoup" id="A0A1C7NM44">
        <property type="interactions" value="137"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NM44"/>
    <dbReference type="InParanoid" id="A0A1C7NM44"/>
    <dbReference type="OrthoDB" id="296187at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048487">
        <property type="term" value="F:beta-tubulin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007023">
        <property type="term" value="P:post-chaperonin tubulin folding pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007021">
        <property type="term" value="P:tubulin complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004226">
        <property type="entry name" value="TBCA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036126">
        <property type="entry name" value="TBCA_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21500">
        <property type="entry name" value="TUBULIN-SPECIFIC CHAPERONE A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21500:SF0">
        <property type="entry name" value="TUBULIN-SPECIFIC CHAPERONE A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02970">
        <property type="entry name" value="TBCA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46988">
        <property type="entry name" value="Tubulin chaperone cofactor A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0143">Chaperone</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="3" id="KW-0493">Microtubule</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU364030"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OBZ90145.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="105" mass="11965" checksum="BB21389EAB8D06AF" modified="2016-11-30" version="1">MPLSQLKIKTNVVKRIYKEHLGYAKEAEMQQSRIDKLIAEGADEADVKKQREVLAETHQMIPDVKKRLTNAYQDLQNQLENSESADLDELQEAQTVIADIGAHTF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NMF5</accession>
    <name>A0A1C7NMF5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_02302</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000085">
        <property type="protein sequence ID" value="OBZ89646.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NMF5"/>
    <dbReference type="STRING" id="101091.A0A1C7NMF5"/>
    <dbReference type="InParanoid" id="A0A1C7NMF5"/>
    <dbReference type="OrthoDB" id="2537769at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012808">
        <property type="entry name" value="CHP02453"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02453">
        <property type="entry name" value="TIGR02453 family protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36452">
        <property type="entry name" value="CHROMOSOME 12, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36452:SF1">
        <property type="entry name" value="DUF2461 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09365">
        <property type="entry name" value="DUF2461"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="42"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ89646.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="325" mass="37177" checksum="173BE9711BF94E8F" modified="2016-11-30" version="1">MVTTLRKRKQGKTIASYEESDSDFASDPELRSKTQQKRAKTASREKKKKQDTETEESDTEVNQLESSSQSDKDESDSDNVTQFKPAKIKVPHPDGSPFPDSLSPKTLEFLAELAENNDRDFMHFKAKEFQEAKQDFIDFCGLIRDELAQVDPSIRLEEPKQAVYRQNRDLRFSNDKRPYKINLSASFSRTGRKFADAGYFLSIRPGNHSMIASGMWQPDKHRLANMRSSIIRHGDLLRESLSTEAIKDVFHGKSGVEILSPEDKLKVAPKDIDKHHPEIELLRYRSFAVVKEFTDQEVVSPGFVEKVMDFLEATVPFVTVVNSWI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NNL3</accession>
    <name>A0A1C7NNL3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Tropomyosin-2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">TPM2_2</name>
        <name evidence="3" type="ORF">A0J61_01388</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000043">
        <property type="protein sequence ID" value="OBZ90560.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NNL3"/>
    <dbReference type="STRING" id="101091.A0A1C7NNL3"/>
    <dbReference type="InParanoid" id="A0A1C7NNL3"/>
    <dbReference type="OrthoDB" id="128924at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.340">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000533">
        <property type="entry name" value="Tropomyosin"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00261">
        <property type="entry name" value="Tropomyosin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57997">
        <property type="entry name" value="Tropomyosin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="1"/>
            <end position="119"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ90560.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="123" mass="14134" checksum="FED6C9ED20E4E780" modified="2016-11-30" version="1">MEKFKEKLATLRNEVDTATKRAQELEEKCKQLEAEHDQKDDELSNLQARAKELEESLETAEANLKQATSDFREADLRAEQLSKKAVKIEQEIATWDKKNAELEAKYQAAKSEMDELEGQMDGM</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-06-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NPN3</accession>
    <name>A0A1C7NPN3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_01005</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000027">
        <property type="protein sequence ID" value="OBZ90940.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NPN3"/>
    <dbReference type="InParanoid" id="A0A1C7NPN3"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ90940.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="77" mass="9270" checksum="29F39F5494BE2C5C" modified="2016-11-30" version="1">MNFRRTRRMAMFYNLEHTHGCFQASLSNSTLAGFEDFKVPNDKNNVSRKEAVHRRHFFPEYLQLLSYLPRPKQKDSY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NPY8</accession>
    <name>A0A1C7NPY8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_00970</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000026">
        <property type="protein sequence ID" value="OBZ90959.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NPY8"/>
    <dbReference type="InParanoid" id="A0A1C7NPY8"/>
    <dbReference type="OrthoDB" id="2289512at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="18"/>
            <end position="33"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ90959.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="265" mass="31167" checksum="C51577A7DE7F3DF7" modified="2016-11-30" version="1">MIRKRTKVNENDVEDQNKSSMKQLGSPNKSFMRNASPALSLKTNQRDQKMTNLNAKQKFQIFKDNKTVPQKRTLVNQEEAQAKKHHTVERTYRRREEEIEWSPVGLDLDFSGLDSSVREYNKEPAFVEPEPMMERRFDQMKETVTQEQEEVTEEEEEDMTTVEYAPPKEKEIPYGPDPSCIVDLSGFSPFADQDAYEFSRFQKLPYQRDDWIDVEEEVNPFVATIDEFDYSDLEPESDLTADNDFSSIPFQDHQLDVDYYVQMHC</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NQ19</accession>
    <name>A0A1C7NQ19_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">CBK1 kinase activator protein MOB2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">MOB2_0</name>
        <name evidence="3" type="ORF">A0J61_00878</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000023">
        <property type="protein sequence ID" value="OBZ91070.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NQ19"/>
    <dbReference type="FunCoup" id="A0A1C7NQ19">
        <property type="interactions" value="108"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NQ19"/>
    <dbReference type="InParanoid" id="A0A1C7NQ19"/>
    <dbReference type="OrthoDB" id="8170117at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.140.30">
        <property type="entry name" value="MOB kinase activator"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005301">
        <property type="entry name" value="MOB_kinase_act_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036703">
        <property type="entry name" value="MOB_kinase_act_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22599">
        <property type="entry name" value="MPS ONE BINDER KINASE ACTIVATOR-LIKE MOB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03637">
        <property type="entry name" value="Mob1_phocein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01388">
        <property type="entry name" value="Mob1_phocein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101152">
        <property type="entry name" value="Mob1/phocein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="19"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="99"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="104"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="179"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="184"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR605301-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ91070.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="236" mass="26885" checksum="23D5AE66772EEC79" modified="2016-11-30" version="1">MMNFLGFSFGKKSSKSSKKSAGSSASSIHSHHANHSSSQLSSKSLCLCSPYVNNMLVKGNFKMITELPKYVDINEWLAFNTFEFFNHINLFYGSITNFCTPQSCPTMSAGSGVEYTWSDSTSKKVRLPASQYIDYMTSSIESMLNDESLFPTKSGPEFPRELHSIVKKMFGQMFRLFAHIYHEHFDKVLCLNEEPHFNSLFAHFISFAREFDLLEKQEMQPLSELINIMLKNGVIC</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NQ42</accession>
    <name>A0A1C7NQ42_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">T-complex protein 11-like protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">TCP11L1</name>
        <name evidence="4" type="ORF">A0J61_00734</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the TCP11 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000018">
        <property type="protein sequence ID" value="OBZ91227.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NQ42"/>
    <dbReference type="STRING" id="101091.A0A1C7NQ42"/>
    <dbReference type="InParanoid" id="A0A1C7NQ42"/>
    <dbReference type="OrthoDB" id="276323at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010737">
        <property type="term" value="P:protein kinase A signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008862">
        <property type="entry name" value="Tcp11"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12832:SF11">
        <property type="entry name" value="LD23868P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12832">
        <property type="entry name" value="TESTIS-SPECIFIC PROTEIN PBS13 T-COMPLEX 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05794">
        <property type="entry name" value="Tcp11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="72"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="315"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="29"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="77"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="87"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="99"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="315"/>
            <end position="336"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OBZ91227.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="788" mass="89755" checksum="E84A5FC0426D7723" modified="2016-11-30" version="1">MAIAESNRNIYIEQRRAYSKRLVDRAKRVALQNQKRSEQEQERRRAELERRLEKTEERRLAHLNRYKLQKKKVIPPSSSSLTSTNTEDTMPTVSTKKITTPPLSPSLTAPKKKPSSWSIILKAFKELGLPSPSSPDTWLEFNALGQLLHQPKVVVVTTKVLNTALKTVDEESRHRARVLLTSYMTLMCPKEVLEDVNGAEEKRLHASAKEMLQLFEVWLKAHGRPGATAARMAFVNAWNDYNLLFESWKSRDCDQLIKNMIIYYVELSTLRQTVIAQSHGDEAVGEQLREQLEQIKAKLQKLGGHEALNNLQRALESSASSTSTGRKKQQQNNTPRSSDEMDMFEQRQQQEKSEQLGQLLSGFAQPTSGITNEFLAHELIMDPEFKLQRHGSTDELEKRVRLMAEKAFFDKLEQDIQQGKADMSLPSVIQDVKMRLLSLVRPHTSLHKQIDEAIDLSLIKQQIKQHSFDMQHMISYVLNTMSGMCAPVRDEEIQNAKASTGMIDQMRSILTILDNMNLDLANFRLRSLRPHLMSIAVEYEREKFATMLNQGTIQLVRTKAWLTDSTQKLCQVAAQRNPEGVLPEKNNKPSHDAVFEDAFVSLLVQPQPIAHLSDLPETLYLDVKRMGEYQNEVQATTMVAALLMLAKNFGSVHQQQLSRLASRLFTMLEDSSTSIDNLALEIERSANVRPERRTMVKTMVDKTINQTDTVYSLLSRRISSVIKNTIQNNQFVTEAVLTSNGLDPIRAQLQSISLKVLRLANHNRKVYSSWYSDIIAEALNENMVAPSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NQC2</accession>
    <name>A0A1C7NQC2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Ammonia transport outward protein 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">ATO2_3</name>
        <name evidence="7" type="ORF">A0J61_00635</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the acetate uptake transporter (AceTr) (TC 2.A.96) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000015">
        <property type="protein sequence ID" value="OBZ91302.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NQC2"/>
    <dbReference type="InParanoid" id="A0A1C7NQC2"/>
    <dbReference type="OrthoDB" id="3648309at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015123">
        <property type="term" value="F:acetate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051633">
        <property type="entry name" value="AceTr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000791">
        <property type="entry name" value="Gpr1/Fun34/SatP-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF038013">
        <property type="entry name" value="AceTr_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31123">
        <property type="entry name" value="ACCUMULATION OF DYADS PROTEIN 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31123:SF1">
        <property type="entry name" value="ACCUMULATION OF DYADS PROTEIN 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01184">
        <property type="entry name" value="Gpr1_Fun34_YaaH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="50"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="82"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="107"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="146"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="170"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="200"/>
            <end position="221"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005587"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OBZ91302.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="233" mass="25559" checksum="156CC6E654524046" modified="2016-11-30" version="1">MSDNLIEKLDIVHQESVIVDMLDKQEVHQQVRSMYAPPPTTELAEFQKTLIGPAIGFAAFALCSFVLGLYNTGLIVDIPHVAVGIAFSYGTIGQFIAGVIEIFHKNVFAATSFITFGSFFFAFGIMMVPGSGFLSTATAAGEVEKSMALVELSYSIAALIFFLGTLRQPILIRLVLGFAFCSFFFPSVGAFSGIITFTRIGGWCSFILSLIAWYTLMALLYNETNTFIRIPFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NQI0</accession>
    <name>A0A1C7NQI0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_00566</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000013">
        <property type="protein sequence ID" value="OBZ91381.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NQI0"/>
    <dbReference type="InParanoid" id="A0A1C7NQI0"/>
    <dbReference type="OrthoDB" id="3210850at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38848">
        <property type="entry name" value="G-PROTEIN COUPLED RECEPTORS FAMILY 3 PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38848:SF3">
        <property type="entry name" value="G-PROTEIN COUPLED RECEPTORS FAMILY 3 PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="40"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="81"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="119"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="268"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="279"/>
            <end position="291"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ91381.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="291" mass="32720" checksum="3E58375E8AA3379E" modified="2016-11-30" version="1">MVCDIFYAGTKIAIYAWLIEKIYVVSSIRQTRWKSKAYRFNASLLLPYIAIFTLMLVFHVAEIDETGACIIGLQNVASLPLLIYDFIINLYMTIFFIKPLTKLGSTSKVGWKASRLNEVALRTLVASIVCLIASFANIFALIMFKGRERGLVCLTCCTVDVTINVITVHWVTSQTPGKRIKDTGADISTHLQRESISNDNEANPAEAFHSNHSDVDLRVAQQTSNKVGEDFYGFTNPDFTHFKAAPPYYPPNDKKTLKQKEVKFDQISADSHISVPSIHESQNSRRSLTKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NQW8</accession>
    <name>A0A1C7NQW8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Mechanosensitive ion channel protein 10</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">MSL10_2</name>
        <name evidence="9" type="ORF">A0J61_02285</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000084">
        <property type="protein sequence ID" value="OBZ89654.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NQW8"/>
    <dbReference type="FunCoup" id="A0A1C7NQW8">
        <property type="interactions" value="4"/>
    </dbReference>
    <dbReference type="InParanoid" id="A0A1C7NQW8"/>
    <dbReference type="OrthoDB" id="544685at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005262">
        <property type="term" value="F:calcium channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006874">
        <property type="term" value="P:intracellular calcium ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010920">
        <property type="entry name" value="LSM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023408">
        <property type="entry name" value="MscS_beta-dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006685">
        <property type="entry name" value="MscS_channel_2nd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058650">
        <property type="entry name" value="Msy1/2-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31323:SF1">
        <property type="entry name" value="MECHANOSENSITIVE ION CHANNEL PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31323">
        <property type="entry name" value="MECHANOSENSITIVE ION CHANNEL PROTEIN MSY2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00924">
        <property type="entry name" value="MS_channel_2nd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25886">
        <property type="entry name" value="Msy1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00054">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50182">
        <property type="entry name" value="Sm-like ribonucleoproteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0106">Calcium</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="61"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="98"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="147"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="196"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="548"/>
            <end position="570"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="8">
        <location>
            <begin position="492"/>
            <end position="527"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="285"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="785"/>
            <end position="827"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="11"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="24"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="289"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="795"/>
            <end position="810"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="6">
        <location>
            <begin position="818"/>
            <end position="827"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OBZ89654.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="846" mass="96798" checksum="A17CF2E3B52DB5EF" modified="2016-11-30" version="1">MMSEDEEKTGIQPSSDDGNTSASEEFDWEQDDPEDKTDNEETVGKAKKSFTFFFLSRKSSLISWIIFIFLTFASIAVCVVIFVKVKPQTDPTLTSYNLALWFTFVAFMFCISFVTQCAVEFIPWIIKNFAGFLFSRQTEILRARLSYYMALRLYIKLVGIGAWAWGSWAFLRWHIQSPANGQLPPYVATLERVMEILFLLALFLFIEKFILQLIVTSFHKKAYGDRLQKNERALRILDKLKRVKRTMPQDFLLKRIKRNKQRNQQTSQNKMYQADTEYNTSKTKFKPIINTNPGTPVSEEVPSTKQTVTFPPTHSLDTLIPIPPLNERHPDASKVIDEKAMQEDMPLDQEEDRGKDVKKKGYLSSMRQKVRRRHHRQTIEQESEIADERDEATTERHLGNFEKTQQPRRPINKRMNTGISGLSSNNSSILDAAFFNSWSIKGGYNRLFKESVLHQDPIRQAKVLARDIYHNIMGTSPVRHYLIESDLYDFFRTISEAREAFRLFDIDTNGDISKRELRAGCIRIYRERKDLARSMRDMSQVTGTLDNILLVVFACIWAVVVMAVFGVNVATQLTPLWSAFIAASFIFGSSAKDAFESILFVFVTHPFDTGDRILIDSENWTVASVGLMVTTFLKWSGDVIYVKNTVLATKYIINCRRTGNTTEALDIQISYHTPTWKIQALGDHMVKWANTYPKLYTPNSTGVNIINLENLNRITLTFYFEHTNNFQDLGGRWLRHNNFMMELKDELQRLCITYSKPDQPVVHAFPDTEESMSEEAKAQLDRYRESEETLRRRYTTSGAYRNVSSRYQNQADSASSQAGGGSGDGGGDSGVTAAGAATVVFTTGAM</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NR57</accession>
    <name>A0A1C7NR57_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Tryptophan-rich sensory protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_00492</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000011">
        <property type="protein sequence ID" value="OBZ91450.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NR57"/>
    <dbReference type="STRING" id="101091.A0A1C7NR57"/>
    <dbReference type="InParanoid" id="A0A1C7NR57"/>
    <dbReference type="OrthoDB" id="5586934at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33802">
        <property type="entry name" value="SI:CH211-161H7.5-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33802:SF1">
        <property type="entry name" value="XK-RELATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="50"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="78"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="105"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="139"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="174"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="202"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="225"/>
            <end position="242"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ91450.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="262" mass="29384" checksum="50CA3E3B68038504" modified="2016-11-30" version="1">MSNLHIAQKVANVVVYLFFLSATVYSLVGPAPDENGGILDGQTYITPSYWIEYVWTLIHVLLGGFVIYQWFEPAHEAAIHGVGWHFVLSVLLNAAWLTLLRQGHYIIGFIFSLLTAASVSFVFYRLSKEYPTNSWWDKLFVHAPFSLWHGWIVFSVVINFFQAFTSVKKDGPSLLIRILVILAILLLTVTAVGYVEYKKKRGDVTGALVIGLGLLAIFTNQHDAWIHWTALAGAIITLIYPARPYVFRLVGRSDSENAPLLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NRD4</accession>
    <name>A0A1C7NRD4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">NTF2-related export protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">NXT2</name>
        <name evidence="3" type="ORF">A0J61_00434</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Has a role in nuclear-cytoplasmic transport of proteins and mRNAs.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000009">
        <property type="protein sequence ID" value="OBZ91520.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NRD4"/>
    <dbReference type="STRING" id="101091.A0A1C7NRD4"/>
    <dbReference type="InParanoid" id="A0A1C7NRD4"/>
    <dbReference type="OrthoDB" id="25408at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051028">
        <property type="term" value="P:mRNA transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006913">
        <property type="term" value="P:nucleocytoplasmic transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00780">
        <property type="entry name" value="NTF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.450.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045875">
        <property type="entry name" value="NTF2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032710">
        <property type="entry name" value="NTF2-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002075">
        <property type="entry name" value="NTF2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018222">
        <property type="entry name" value="Nuclear_transport_factor_2_euk"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12612">
        <property type="entry name" value="NUCLEAR TRANSPORT FACTOR 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02136">
        <property type="entry name" value="NTF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54427">
        <property type="entry name" value="NTF2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50177">
        <property type="entry name" value="NTF2_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="1" id="KW-0653">Protein transport</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="domain" description="NTF2" evidence="2">
        <location>
            <begin position="11"/>
            <end position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU369002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ91520.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="132" mass="15097" checksum="1F63EF9D1556D6B7" modified="2016-11-30" version="1">MDVIVNVAEKSTEQFIQFFYPNYDKQRQNLGSLYRDNSAILWNGNAFSGAQQYSEFLGRLPMSHHEIDVYDCHPLPNTMNAQGTCGILINTSGTVKYGDNPSKRTFSQCFILMPDEKQAGNYYVQSDTFRFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NRL3</accession>
    <name>A0A1C7NRL3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Aspartate-semialdehyde dehydrogenase</fullName>
            <ecNumber evidence="4">1.2.1.11</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">A0J61_02052</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Catalyzes the NADPH-dependent formation of L-aspartate 4-semialdehyde (L-ASA) by the reductive dephosphorylation of 4-phospho-L-aspartate. Mediates the second step in the biosynthesis of amino acids that derive from aspartate (the aspartate family of amino acids), including methioinine and threonine, the latter of which is a precursor to isoleucine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>L-aspartate 4-semialdehyde + phosphate + NADP(+) = 4-phospho-L-aspartate + NADPH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:24284"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57535"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:537519"/>
            <dbReference type="EC" id="1.2.1.11"/>
        </reaction>
        <physiologicalReaction direction="right-to-left" evidence="10">
            <dbReference type="Rhea" id="RHEA:24286"/>
        </physiologicalReaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Amino-acid biosynthesis; L-methionine biosynthesis via de novo pathway; L-homoserine from L-aspartate: step 2/3.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2">Amino-acid biosynthesis; L-threonine biosynthesis; L-threonine from L-aspartate: step 2/5.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the aspartate-semialdehyde dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.2.1.11" evidence="4"/>
    <dbReference type="EMBL" id="LUGH01000073">
        <property type="protein sequence ID" value="OBZ89884.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NRL3"/>
    <dbReference type="FunCoup" id="A0A1C7NRL3">
        <property type="interactions" value="272"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NRL3"/>
    <dbReference type="InParanoid" id="A0A1C7NRL3"/>
    <dbReference type="OrthoDB" id="1894490at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004073">
        <property type="term" value="F:aspartate-semialdehyde dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009090">
        <property type="term" value="P:homoserine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009086">
        <property type="term" value="P:methionine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009088">
        <property type="term" value="P:threonine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd18130">
        <property type="entry name" value="ASADH_C_arch_fung_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd02315">
        <property type="entry name" value="ScASADH_like_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000200">
        <property type="entry name" value="Aspartate-semialdehyde dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.360.10:FF:000016">
        <property type="entry name" value="Probable aspartate-semialdehyde dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.360.10">
        <property type="entry name" value="Dihydrodipicolinate Reductase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051823">
        <property type="entry name" value="ASADH-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005676">
        <property type="entry name" value="Asp_semi-ald_DH_pep-lack"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000534">
        <property type="entry name" value="Semialdehyde_DH_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012280">
        <property type="entry name" value="Semialdhyde_DH_dimer_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00978">
        <property type="entry name" value="asd_EA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006416">
        <property type="entry name" value="PRK08664.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46718">
        <property type="entry name" value="ASPARTATE-SEMIALDEHYDE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46718:SF1">
        <property type="entry name" value="ASPARTATE-SEMIALDEHYDE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01118">
        <property type="entry name" value="Semialdhyde_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02774">
        <property type="entry name" value="Semialdhyde_dhC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000148">
        <property type="entry name" value="ASA_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00859">
        <property type="entry name" value="Semialdhyde_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55347">
        <property type="entry name" value="Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="9" id="KW-0486">Methionine biosynthesis</keyword>
    <keyword evidence="7" id="KW-0521">NADP</keyword>
    <keyword evidence="8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0791">Threonine biosynthesis</keyword>
    <feature type="domain" description="Semialdehyde dehydrogenase NAD-binding" evidence="14">
        <location>
            <begin position="6"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="active site" description="Acyl-thioester intermediate" evidence="13">
        <location>
            <position position="152"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="13">
        <location>
            <position position="249"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005021"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010584"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013120"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00049864"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00049950"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00050041"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR000148-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="SMART" id="SM00859"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="OBZ89884.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="357" mass="38422" checksum="08D4A65041EAD222" modified="2016-11-30" version="1">MAPTKKVGILGATGTVGQRFILLLSEHPIFTIHALGASSRSAGKAYKDAVRWKQSRPIPDNVAQLVVKSCEAELFKDCDVVFSGLDADVAGDIEMAMLKQDIAVFSNAKNYRRDPTVPLIVPTVNADHFDLIPHQRQLNNLKKGFLITNANCSTTGLVVPLKALQDAFGPMSHIIVNTQQAISGAGYPGVPSLDILDNVVPHIGGEEEKIEWEVGKIIGDISEDKKSFVLLPNTIVSATCTRVPVLDGHLESVSVKFANGSPSVEQVYQVLEQYSSEAEKLGCHSAPQKPIVVTYDADRPQPRLDRENLKGQAVTVGRVRPCPVLDIKFVLLIHNTVLGAAGSSVLNAEIAVAKGLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NSE1</accession>
    <name>A0A1C7NSE1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Dilute domain-containing protein C25B8.08</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">A0J61_01712</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000057">
        <property type="protein sequence ID" value="OBZ90254.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NSE1"/>
    <dbReference type="STRING" id="101091.A0A1C7NSE1"/>
    <dbReference type="InParanoid" id="A0A1C7NSE1"/>
    <dbReference type="OrthoDB" id="426293at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051020">
        <property type="term" value="F:GTPase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd15473">
        <property type="entry name" value="Myo5p-like_CBD_DIL_ANK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002710">
        <property type="entry name" value="Dilute_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037986">
        <property type="entry name" value="Myo5p-like_CBD_DIL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052072">
        <property type="entry name" value="Vascular_dev_regulator"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16027:SF6">
        <property type="entry name" value="DILUTE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16027">
        <property type="entry name" value="DILUTE DOMAIN-CONTAINING PROTEIN YPR089W"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01843">
        <property type="entry name" value="DIL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM01132">
        <property type="entry name" value="DIL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51126">
        <property type="entry name" value="DILUTE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="repeat" description="ANK" evidence="1">
        <location>
            <begin position="109"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="1">
        <location>
            <begin position="142"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="domain" description="Dilute" evidence="3">
        <location>
            <begin position="307"/>
            <end position="582"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="16"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OBZ90254.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="729" mass="84398" checksum="19E7CE61B83A1662" modified="2016-11-30" version="1">MNQQSDHVKRKNRQNTFSWSTSSSCSTLLTNHDEDNDELEREHDSIHLYAYNSFLQDWTVADDDKKQHVITKFICRSASHGDVQALRHTLMNSSLSPFLNLDLSDDENDGLTPLIYASCFGKLDVVKCLLEAGAKVDVQDNTGWTALMWATTNGHTSIVQVLLAYSASSEAKSKNGRTIFDLVDLENDKMMSAIHLNVPKEEKKRRSIQPTLETVEKTIEDNEQEQIESCKASFRSVHKFVWNQCLPDQMFVFAEEEMDYILNIAITELRLPMKSKGEIYVPANIIFLCARFAHYFTNRELLHQLLSSSIDKMKQVIQLHENDIHTLAFWIANLSQLLYYLKKDAGLVVATAEYQLELSELISESYNFLVIDSENRLGQILEAAMLEFEPIEVEAVEFADDWQRFFRRSRFSVSSQRKSWASQEMIPKALLSPQSIVNLLTSILYVLQSYEVHPVIVIQAIAQLFHFLSCEVFNHVLSNKQYLARSKALQIRMNMTVFEEWIREHQLPMTLSIYFDPVIQLLQVLQCVSQLTDLMDFITTTKTFHLLNPIQLKRVVLNYRYEVSEARLPEEIEKYAMQLAEDTIKSLKEEKKKRRTSCADKQIRPTSVSSLGSLLHFTVSQEHGLRLLDGSLELELEEEEEDSMMETDNRDCIIEKRDSKYMLPFSLPTTTNYLNWKDKQPQAPETNKLSDTIYFELKQKLLAEKDARESNIVPSIPEDWLQRLDHHTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NSZ0</accession>
    <name>A0A1C7NSZ0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF1279 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_01320</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000040">
        <property type="protein sequence ID" value="OBZ90624.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NSZ0"/>
    <dbReference type="FunCoup" id="A0A1C7NSZ0">
        <property type="interactions" value="212"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NSZ0"/>
    <dbReference type="InParanoid" id="A0A1C7NSZ0"/>
    <dbReference type="OrthoDB" id="426386at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045866">
        <property type="entry name" value="FAM210A/B-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009688">
        <property type="entry name" value="FAM210A/B-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21377">
        <property type="entry name" value="PROTEIN FAM210B, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21377:SF0">
        <property type="entry name" value="PROTEIN FAM210B, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06916">
        <property type="entry name" value="FAM210A-B_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="23"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="domain" description="DUF1279" evidence="2">
        <location>
            <begin position="15"/>
            <end position="115"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF06916"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ90624.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="137" mass="15341" checksum="4D720528B07896C7" modified="2016-11-30" version="1">MTTTSNEAPKPFIARTKHYMKKYGYVGIGVYCILGAIDLSAIMAVISVKGAERVRDAEDYAISKAKGWLGIKHTPRTPNSIHERPSFTSLFVIAYGIHKTILLPFRLSLTAAITPTVARRLKELGWIRTKIPKDRKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NT93</accession>
    <name>A0A1C7NT93_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Protein MAM3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">MAM3_0</name>
        <name evidence="12" type="ORF">A0J61_00059</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000001">
        <property type="protein sequence ID" value="OBZ91946.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NT93"/>
    <dbReference type="FunCoup" id="A0A1C7NT93">
        <property type="interactions" value="325"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NT93"/>
    <dbReference type="InParanoid" id="A0A1C7NT93"/>
    <dbReference type="OrthoDB" id="5353557at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030026">
        <property type="term" value="P:intracellular manganese ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010960">
        <property type="term" value="P:magnesium ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04590">
        <property type="entry name" value="CBS_pair_CorC_HlyC_assoc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.580.10:FF:000006">
        <property type="entry name" value="DUF21 and CBS domain protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.580.10">
        <property type="entry name" value="CBS-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045095">
        <property type="entry name" value="ACDP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000644">
        <property type="entry name" value="CBS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046342">
        <property type="entry name" value="CBS_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002550">
        <property type="entry name" value="CNNM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044751">
        <property type="entry name" value="Ion_transp-like_CBS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12064">
        <property type="entry name" value="METAL TRANSPORTER CNNM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12064:SF97">
        <property type="entry name" value="METAL TRANSPORTER CNNM-5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01595">
        <property type="entry name" value="CNNM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54631">
        <property type="entry name" value="CBS-domain pair"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51371">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51846">
        <property type="entry name" value="CNNM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0129">CBS domain</keyword>
    <keyword evidence="5 7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 7 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="53"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="135"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="162"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="domain" description="CNNM transmembrane" evidence="11">
        <location>
            <begin position="45"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="10">
        <location>
            <begin position="250"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="10">
        <location>
            <begin position="316"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="401"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="446"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="401"/>
            <end position="415"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="OBZ91946.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="468" mass="51091" checksum="157445E373A18921" modified="2016-11-30" version="1">MSNIYSISKTRTLVVAAASLFTSIYGQPLNPYAEPEAEEPEIDYGSAEFYEKLVIIFGLVIIGGVFAGLTLGLMGLDETNLHVLTQSGSETEKKHAKQVLRLLHRGKHWVLVTLLLSNVIVNETLPIILDGVLGGGWKAVVISTALIVIFGEVIPQSICVRYGLAIGAKTAPMVLALMYVMYPIAYPTAKLLDYVLGESHGTIYKKAGLKSLVSLHQSVNPADVDALTEDEVTIIGAVLDLRSKPVSQIMTPIADVFTLSTDDILNEELVDKILIAGYSRIPVHAPNDKMNFVGMLLTKRLITYDPEDASPVKSLQISTLPETGPDTSCLDILNFFQEGKSHMALISNEPGANSGALGVITLEDVIEELIGEEIIDETDVYVDVHNKIRVVRRQVHNSRRNSRLTRLLSAHKRKPARENSAGSAHDGSKKVVEPYLKPVYGAVNDTSILSTSPEQHKGENQPLLNNRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-06-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NU22</accession>
    <name>A0A1C7NU22_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_00955</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000025">
        <property type="protein sequence ID" value="OBZ91004.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NU22"/>
    <dbReference type="InParanoid" id="A0A1C7NU22"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ91004.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="100" mass="11461" checksum="AAFB0AC8C83934E8" modified="2016-11-30" version="1">MRDHFLALAESFAIWSRSKLDENSVLFPFSDRIDLFSVCVQYRLHITSAWGQDDSEGDLNGEIVEIDTLLSEERLLRIRGDSRFLRAKAVLLEKLGDSDT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7LJT6</accession>
    <name>A0A1C7LJT6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_11954</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01002763">
        <property type="protein sequence ID" value="OBZ64426.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7LJT6"/>
    <dbReference type="InParanoid" id="A0A1C7LJT6"/>
    <dbReference type="OrthoDB" id="2289822at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ64426.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="66" mass="7632" checksum="0B17A3491CB8981A" modified="2016-11-30" version="1" fragment="single">MGSLRTLEELKNGDRAHGMPGVPKLFTELKTFISPYFFFGDELHMLGHDMGHMVYKLLDPKTSDWF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7LP23</accession>
    <name>A0A1C7LP23_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_11917</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01002691">
        <property type="protein sequence ID" value="OBZ66521.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7LP23"/>
    <dbReference type="STRING" id="101091.A0A1C7LP23"/>
    <dbReference type="InParanoid" id="A0A1C7LP23"/>
    <dbReference type="OrthoDB" id="2206543at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="6"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ66521.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="307" mass="32636" checksum="015C0D4AE5176A2E" modified="2016-11-30" version="1" fragment="single">AKFEKYEERLSQLESLVAENAALKKELEAVRANISQLESMPGPSCASLVVSSVSSGSSTPVASSSGPVSKSTTVAAAAYAPAPTSGEAYGKSKKLVSSCPSGAAVQAKSKVKITSLHRNAAARIFAVSSPPAGSPVDGPLFEYVYLPNKYRARLSVFRQKLRLIGLNNSRVLDVHYPARHVVALLFHTAYKGDLLKVLNKYSLPVLIDFDPFSVANVRNPSFASFNKDALTTKAHELQQAHLVRALGYIREQTRRLVVYDFVCQGWLCKEQASSAIGSLSSAAGVDSASSADMDITLTGAGEPASLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7M2E4</accession>
    <name>A0A1C7M2E4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_11890</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01002649">
        <property type="protein sequence ID" value="OBZ71065.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7M2E4"/>
    <dbReference type="InParanoid" id="A0A1C7M2E4"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ71065.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="109" mass="11883" checksum="4813D57D85DE0805" modified="2016-11-30" version="1" fragment="single">MDLHEESSEAKRPVSLKAAIAALEVRRNAIADRVSNMILNNKDEQATASLIIQVDVISKQVDTLNALKKSKEPVARAGTPVSKKDVPMFQLKAHDVVSFPGEEVFASVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-06-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MUH9</accession>
    <name>A0A1C7MUH9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_11479</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01002089">
        <property type="protein sequence ID" value="OBZ80472.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MUH9"/>
    <dbReference type="InParanoid" id="A0A1C7MUH9"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ80472.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="176" mass="20265" checksum="B878EA936CD7B351" modified="2016-11-30" version="1">MEVGYKIRRLKEEEPAFINLVLGHRKNADNNDYAEQARRTLRKGTTGYFNCSAPGYNGCFFGRIDDVIDDSAEYSITVYDIEQFDPFVSSANSGRVRSSFLFPNWLATRDNNIVLCQSGSRRVLASEIQLKNRLDMQSTIEVYNLTTSERGERTLLNVHEYGNLWFLHRMNNSMIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MUL4</accession>
    <name>A0A1C7MUL4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_11451</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01002044">
        <property type="protein sequence ID" value="OBZ80500.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MUL4"/>
    <dbReference type="InParanoid" id="A0A1C7MUL4"/>
    <dbReference type="OrthoDB" id="2284753at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ80500.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="139" mass="15381" checksum="FCD40629CBC8A557" modified="2016-11-30" version="1" fragment="single">MPRLGSELPCPIDHEEVTNAVNASPLSTSTERPHFTNQLRSLLDDNANIDLKSTYCNLPNAIVDLETKPGTIAFPKSLFIICYDYSPIKRKIVKQVVPIETSVNKINAVGTYCLCSTCLIFQFPEASARKVVSLLVLIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MW67</accession>
    <name>A0A1C7MW67_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">TLC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">A0J61_10942</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001528">
        <property type="protein sequence ID" value="OBZ81008.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MW67"/>
    <dbReference type="STRING" id="101091.A0A1C7MW67"/>
    <dbReference type="InParanoid" id="A0A1C7MW67"/>
    <dbReference type="OrthoDB" id="341353at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055088">
        <property type="term" value="P:lipid homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006634">
        <property type="entry name" value="TLC-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050846">
        <property type="entry name" value="TLCD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13439">
        <property type="entry name" value="CT120 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13439:SF72">
        <property type="entry name" value="TLC DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50922">
        <property type="entry name" value="TLC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="15"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="53"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="92"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="126"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="171"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="200"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="domain" description="TLC" evidence="7">
        <location>
            <begin position="45"/>
            <end position="228"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00205"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OBZ81008.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="244" mass="28930" checksum="D9DD77E6358278BD" modified="2016-11-30" version="1">MTMLELSQIFGQSTVQYSFAFSTLLFVSGFYIFRYHICKNGSHEKTREKQTSWILTLISSLICTVVSIPFVIQFFCADLNMQLLSTDNQFHTAFVCFFITYLILDLILGCIYYRKRITLMTGWIHHLFYIVLLTCFMRLQISSLFTVSSILELPTLVLAAGSMVHEWRSDLLFGTTFFVLRLVAHAWMMVNLKRYHRIEFMWVIALVIYPLHIYWFYGIIQIQLRKFINYRKMQHLAQKAKYPI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MWL6</accession>
    <name>A0A1C7MWL6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">CCHC-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">A0J61_10783</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001390">
        <property type="protein sequence ID" value="OBZ81168.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MWL6"/>
    <dbReference type="STRING" id="101091.A0A1C7MWL6"/>
    <dbReference type="InParanoid" id="A0A1C7MWL6"/>
    <dbReference type="OrthoDB" id="2287232at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.60.10">
        <property type="entry name" value="Zinc finger, CCHC-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001878">
        <property type="entry name" value="Znf_CCHC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036875">
        <property type="entry name" value="Znf_CCHC_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00098">
        <property type="entry name" value="zf-CCHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00343">
        <property type="entry name" value="ZnF_C2HC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57756">
        <property type="entry name" value="Retrovirus zinc finger-like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50158">
        <property type="entry name" value="ZF_CCHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="CCHC-type" evidence="3">
        <location>
            <begin position="281"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="296"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="310"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="346"/>
            <end position="356"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OBZ81168.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="356" mass="39349" checksum="61A019547939ABC4" modified="2016-11-30" version="1">MTTSFRHNMALPANTHKRTIQTPTTYKTNKKSWVDAVNEGIRRTSSSACDPSSTKPSVEPGQLPESAVRDVYSHVARPFLKGTVSNSLLIDITATSDIKTFIQELHEVRNGNYSRVFAEIVVSPSKYSQFIQAGFKLKTQGNFSAFPSLSSSSEILKISLSGLSSQYGRLQGGLDQLCTDMCCGQWFNHHSTGVYTENGYVVLEIKSSESSNSPPHSLSNLIDYSYQPINYQESAQLCLHKNFDRVQVKATWASMPPFCRFCHSPEHALADCLLRRKATTCFHCNELGHISRVCPRKNSGVGKKRKTPVANVSSTAPLESYADSQPRQAVWPTSVPSTSLVRERSSSSQTSSPIIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MWZ6</accession>
    <name>A0A1C7MWZ6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_10981</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001560">
        <property type="protein sequence ID" value="OBZ80969.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MWZ6"/>
    <dbReference type="STRING" id="101091.A0A1C7MWZ6"/>
    <dbReference type="InParanoid" id="A0A1C7MWZ6"/>
    <dbReference type="OrthoDB" id="2272012at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005085">
        <property type="term" value="F:guanyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.900.10">
        <property type="entry name" value="Dbl homology (DH) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035899">
        <property type="entry name" value="DBL_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000219">
        <property type="entry name" value="DH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052233">
        <property type="entry name" value="Rho-type_GEFs"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46572">
        <property type="entry name" value="RHO1 GDP-GTP EXCHANGE PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46572:SF1">
        <property type="entry name" value="RHO1 GUANINE NUCLEOTIDE EXCHANGE FACTOR TUS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48065">
        <property type="entry name" value="DBL homology domain (DH-domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50010">
        <property type="entry name" value="DH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DH" evidence="2">
        <location>
            <begin position="162"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="232"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ80969.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="232" mass="26351" checksum="FE3A9535305A6E6E" modified="2016-11-30" version="1" fragment="single">MSTKGNVRIGADSQKGGGNRLKKESTGFVRLNHGCLSVIARQFVDKVIYAQISTEEALNACEAILNHTELSKHDLLHSLIQNKILSEGHKDILMIQNTSLQAIVVKLTDCYSPLCTSSVRCYSPTCPRRSLNHLHLIENKLSTFDSSIPEYILNNLSSKEKKRQLAIEELRNYEHNFLRQLKVIHDIFAQPLLQSTAIEAPRRHLFHDHLFGNYLALATLHKGLFRDLELSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-06-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MX76</accession>
    <name>A0A1C7MX76_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_10515</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001212">
        <property type="protein sequence ID" value="OBZ81437.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MX76"/>
    <dbReference type="InParanoid" id="A0A1C7MX76"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="127"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ81437.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="127" mass="14216" checksum="21B4169C5A73005B" modified="2016-11-30" version="1" fragment="single">MSPTLLTPISTESNSTKQLIWCYDNDVNVLNVVLLAYQHVLQKYPAYSTKTELVLLKQPEIQLPERVKIVDHFSEEGKPCVKIALKTSVDTHDTMTPTLVSIVSKPNHIQTNPSDYAAMATHLKNAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MY59</accession>
    <name>A0A1C7MY59_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_10218</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001076">
        <property type="protein sequence ID" value="OBZ81732.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MY59"/>
    <dbReference type="InParanoid" id="A0A1C7MY59"/>
    <dbReference type="OrthoDB" id="10439068at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ81732.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="107" mass="12094" checksum="93C9A497BC038643" modified="2016-11-30" version="1">MELARRDAPSVKVNALNVDKSRQKARHVTPPFTGVGARGWLQQFKKLIKNHKYSDTDALMEMMIYMQGAANDLWPTLSEIQHNNLHQAILAFQAFCGDEEDAMAHAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MYP8</accession>
    <name>A0A1C7MYP8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Alkyl transferase</fullName>
            <ecNumber evidence="5">2.5.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">A0J61_10040</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the CMC family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the UPP synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.-" evidence="5"/>
    <dbReference type="EMBL" id="LUGH01001010">
        <property type="protein sequence ID" value="OBZ81911.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MYP8"/>
    <dbReference type="FunCoup" id="A0A1C7MYP8">
        <property type="interactions" value="511"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7MYP8"/>
    <dbReference type="InParanoid" id="A0A1C7MYP8"/>
    <dbReference type="OrthoDB" id="4173905at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1904423">
        <property type="term" value="C:dehydrodolichyl diphosphate synthase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005811">
        <property type="term" value="C:lipid droplet"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045547">
        <property type="term" value="F:ditrans,polycis-polyprenyl diphosphate synthase [(2E,6E)-farnesyl diphosphate specific] activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016094">
        <property type="term" value="P:polyprenol biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00475">
        <property type="entry name" value="Cis_IPPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1180.10">
        <property type="entry name" value="Decaprenyl diphosphate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013892">
        <property type="entry name" value="Cyt_c_biogenesis_Cmc1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001441">
        <property type="entry name" value="UPP_synth-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036424">
        <property type="entry name" value="UPP_synth-like_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00055">
        <property type="entry name" value="uppS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10291:SF43">
        <property type="entry name" value="DEHYDRODOLICHYL DIPHOSPHATE SYNTHASE COMPLEX SUBUNIT DHDDS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10291">
        <property type="entry name" value="DEHYDRODOLICHYL DIPHOSPHATE SYNTHASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08583">
        <property type="entry name" value="Cmc1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01255">
        <property type="entry name" value="Prenyltransf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64005">
        <property type="entry name" value="Undecaprenyl diphosphate synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="264"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="275"/>
            <end position="296"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU363018"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OBZ81911.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="296" mass="34034" checksum="C88915C03CEEC1AB" modified="2016-11-30" version="1">MILSLCQNYLEQLTVSILRKGRIPRHVGFILDGNRRFAKKHGASSTQYGHYQGFRQLEKVLDLCMQLGIEAVSVYAFSLENFKRSKDEVDYLMQLICDAFDGFCEKNALVEKYEISVRFVGNLDLLPDHVHNLANDVMEKTKQNKKRIFNVCCPYTSRDEMTTAIRQTATLVEQGKLRLEEINAKTIEDHLFTADCPPMDILSYYTMHPQLEAHKNEGCDGVIQALEKCHRAGTFNKFIGTCNAAKRAVDDCLQREFLAQRAVNKEKTKAKRKKMEQIWKEMEEPPADLKEKTTAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MYQ3</accession>
    <name>A0A1C7MYQ3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_11707</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01002370">
        <property type="protein sequence ID" value="OBZ80244.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MYQ3"/>
    <dbReference type="InParanoid" id="A0A1C7MYQ3"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="12"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ80244.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="27" mass="3104" checksum="3BB312E5EE6491A8" modified="2016-11-30" version="1" fragment="single">NKKPDRLRRPKMPAADPAMAAKQERIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MZ43</accession>
    <name>A0A1C7MZ43_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">60S ribosomal protein L21-A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">RPL21A</name>
        <name evidence="4" type="ORF">A0J61_10273</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the eukaryotic ribosomal protein eL21 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001098">
        <property type="protein sequence ID" value="OBZ81679.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MZ43"/>
    <dbReference type="FunCoup" id="A0A1C7MZ43">
        <property type="interactions" value="529"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7MZ43"/>
    <dbReference type="InParanoid" id="A0A1C7MZ43"/>
    <dbReference type="OrthoDB" id="1539250at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.30.70:FF:000001">
        <property type="entry name" value="60S ribosomal protein L21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="6.10.250.3260:FF:000001">
        <property type="entry name" value="60S ribosomal protein L21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.3260">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.70">
        <property type="entry name" value="Ribosomal protein L21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001147">
        <property type="entry name" value="Ribosomal_eL21"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018259">
        <property type="entry name" value="Ribosomal_eL21_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036948">
        <property type="entry name" value="Ribosomal_eL21_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008991">
        <property type="entry name" value="Translation_prot_SH3-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20981">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01157">
        <property type="entry name" value="Ribosomal_L21e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50104">
        <property type="entry name" value="Translation proteins SH3-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01171">
        <property type="entry name" value="RIBOSOMAL_L21E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008427"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OBZ81679.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="160" mass="18389" checksum="C3E1E4ECD04E021B" modified="2016-11-30" version="1">MPHSFGLRARTRHMFSRNFREHGAIPLSTYLKTYKVGDIVDIKANAAVQKGMPHKFYHGRTGVIYNVTKTSVGVIVHKKVGNRFMEKRVNIRIEHIKHSKCRQEFLDRVKANAQKKKEAKEAGVSFNLKRLPVQPREARHVSTKFNVPQTIAPIAYETLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MZA5</accession>
    <name>A0A1C7MZA5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_09796</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000939">
        <property type="protein sequence ID" value="OBZ82153.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MZA5"/>
    <dbReference type="InParanoid" id="A0A1C7MZA5"/>
    <dbReference type="OrthoDB" id="2298538at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ82153.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="85" mass="9350" checksum="0232E9A2FA32FBEC" modified="2016-11-30" version="1">MDNGGSPLPEAKTVSFEDADFASGNFNYKHELELLAKSNAQAVEAETALSRQDLTTVKNEEGILNAYKCLQDNKTLLPEFQDEQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MZK7</accession>
    <name>A0A1C7MZK7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Iron-sulfur assembly protein 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">ISA1</name>
        <name evidence="5" type="ORF">A0J61_09752</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Involved in the assembly of mitochondrial and cytoplasmic iron-sulfur proteins. Probably involved in the binding of an intermediate of Fe/S cluster assembly.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the HesB/IscA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000928">
        <property type="protein sequence ID" value="OBZ82201.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MZK7"/>
    <dbReference type="FunCoup" id="A0A1C7MZK7">
        <property type="interactions" value="392"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7MZK7"/>
    <dbReference type="InParanoid" id="A0A1C7MZK7"/>
    <dbReference type="OrthoDB" id="333486at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036455">
        <property type="term" value="F:iron-sulfur transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044572">
        <property type="term" value="P:[4Fe-4S] cluster assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009102">
        <property type="term" value="P:biotin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051604">
        <property type="term" value="P:protein maturation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.300.12:FF:000001">
        <property type="entry name" value="Iron-binding protein IscA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.300.12">
        <property type="entry name" value="HesB-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016092">
        <property type="entry name" value="ATAP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000361">
        <property type="entry name" value="ATAP_core_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050322">
        <property type="entry name" value="Fe-S_cluster_asmbl/transfer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017870">
        <property type="entry name" value="FeS_cluster_insertion_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035903">
        <property type="entry name" value="HesB-like_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00049">
        <property type="entry name" value="iron-sulfur cluster assembly accessory protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10072:SF41">
        <property type="entry name" value="IRON-SULFUR CLUSTER ASSEMBLY 1 HOMOLOG, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10072">
        <property type="entry name" value="IRON-SULFUR CLUSTER ASSEMBLY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01521">
        <property type="entry name" value="Fe-S_biosyn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89360">
        <property type="entry name" value="HesB-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01152">
        <property type="entry name" value="HESB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Core" evidence="4">
        <location>
            <begin position="29"/>
            <end position="128"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006718"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00054873"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00071673"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01521"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OBZ82201.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="132" mass="14128" checksum="57E274B134307CD2" modified="2016-11-30" version="1">MPIGAVVKQAAANSMKAPGSRLRLRKAALTLTPAAVSRLKTLTEGPTPQYLRVGVKQKGCSGNSYDLQFTDHKGKFDEIVNQDGVTVLVDSKALITILGSEMDFVQDKLSEHFVFNNPNAKGTCGCGESFAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N0B4</accession>
    <name>A0A1C7N0B4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Transcription activator of gluconeogenesis ERT1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">ERT1_2</name>
        <name evidence="11" type="ORF">A0J61_09353</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ERT1/acuK family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000830">
        <property type="protein sequence ID" value="OBZ82595.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N0B4"/>
    <dbReference type="STRING" id="101091.A0A1C7N0B4"/>
    <dbReference type="InParanoid" id="A0A1C7N0B4"/>
    <dbReference type="OrthoDB" id="2538135at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006094">
        <property type="term" value="P:gluconeogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050335">
        <property type="entry name" value="ERT1_acuK_gluconeogen_tf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056751">
        <property type="entry name" value="PAS_13"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47659:SF1">
        <property type="entry name" value="TRANSCRIPTION ACTIVATOR OF GLUCONEOGENESIS ERT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47659">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24990">
        <property type="entry name" value="PAS_13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3" id="KW-0312">Gluconeogenesis</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0804">Transcription</keyword>
    <keyword evidence="5" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="10">
        <location>
            <begin position="13"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="167"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="9">
        <location>
            <begin position="171"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="202"/>
            <end position="220"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010855"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="OBZ82595.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="419" mass="47250" checksum="D5B6DE2771BC7F16" modified="2016-11-30" version="1">MENTEKRKNLPDTCTHCQKANLICDKGRPCQGCVKRNLMNTCTDRNKKCKTDTDTPSDELYSPTANVPFTPADQPLDTSSLFNLSFADFGFGSEATGLEYNILSSISVNDKPDSIRNTTNSPTLTIPTTTEIIDTTSSNSQLFNALSSLFPFTSPSASTINQPVQMHFQLPKPPTPTVEPPQRQPSLTYTSPVQKNAKRDSVASTVSTSSSTAAQKSSTGNRRKGNNGNTPEAVYNSVRKPFNYAEGFHYLIQYVTERMRHDDLMRISRALSFFRPSFLSLIMNLTEEDLIFMERCFQRTLLEYEKLISFSGTPTVVWRRTGEVCLVGKEFSLLTQWTRDMLLNKKTYIYELMENQSAVEYWEKFSIHAFDNTDKACSYSCILRTPQQKPVPCTFCFTIKRDIFDLPSVIVGNVSSTVH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-06-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N0P4</accession>
    <name>A0A1C7N0P4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_09232</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000804">
        <property type="protein sequence ID" value="OBZ82715.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N0P4"/>
    <dbReference type="InParanoid" id="A0A1C7N0P4"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ82715.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="99" mass="10702" checksum="1C4116AED5F2E198" modified="2016-11-30" version="1">MTVNAPINTEQAHLLRLPVTVGDLMPLESPSVMPTPTSAPPTVVFFFIRNTELTSYLQHATHPNIYKTTDVSASNLAAAGTTADLPIITTDLSNKINRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N0U1</accession>
    <name>A0A1C7N0U1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Negative cofactor 2 complex subunit beta</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">ncb2</name>
        <name evidence="4" type="ORF">A0J61_09674</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000906">
        <property type="protein sequence ID" value="OBZ82276.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N0U1"/>
    <dbReference type="FunCoup" id="A0A1C7N0U1">
        <property type="interactions" value="522"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N0U1"/>
    <dbReference type="InParanoid" id="A0A1C7N0U1"/>
    <dbReference type="OrthoDB" id="601405at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017054">
        <property type="term" value="C:negative cofactor 2 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003682">
        <property type="term" value="F:chromatin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001046">
        <property type="term" value="F:core promoter sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046982">
        <property type="term" value="F:protein heterodimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016251">
        <property type="term" value="F:RNA polymerase II general transcription initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017025">
        <property type="term" value="F:TBP-class protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003713">
        <property type="term" value="F:transcription coactivator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003714">
        <property type="term" value="F:transcription corepressor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034605">
        <property type="term" value="P:cellular response to heat"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017055">
        <property type="term" value="P:negative regulation of RNA polymerase II transcription preinitiation complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016480">
        <property type="term" value="P:negative regulation of transcription by RNA polymerase III"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051123">
        <property type="term" value="P:RNA polymerase II preinitiation complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd22905">
        <property type="entry name" value="HFD_Dr1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.20.10">
        <property type="entry name" value="Histone, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003958">
        <property type="entry name" value="CBFA_NFYB_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009072">
        <property type="entry name" value="Histone-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042225">
        <property type="entry name" value="Ncb2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46138">
        <property type="entry name" value="PROTEIN DR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46138:SF1">
        <property type="entry name" value="PROTEIN DR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00808">
        <property type="entry name" value="CBFD_NFYB_HMF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47113">
        <property type="entry name" value="Histone-fold"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Transcription factor CBF/NF-Y/archaeal histone" evidence="3">
        <location>
            <begin position="68"/>
            <end position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00808"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OBZ82276.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="163" mass="18839" checksum="7CD2C25CDC156B30" modified="2016-11-30" version="1">MSDSERAGNPVDDELSLPKATVQKLINEMMPDDIVCSKDTRDLLIDCCVGKTSETRGYFSMTDRFCLLSEFIHLIASEANEICEKETKKTIAGEHVLSALKELGFEDYMEEVDEVFKEHKKQQKDRDRKSTRLENRGISEEELLRQQELLFAQSRIKFEAQQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N277</accession>
    <name>A0A1C7N277_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Globin-sensor domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_09154</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000785">
        <property type="protein sequence ID" value="OBZ82796.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N277"/>
    <dbReference type="InParanoid" id="A0A1C7N277"/>
    <dbReference type="OrthoDB" id="10027058at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ82796.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="93" mass="10044" checksum="72756040BF5E7F1F" modified="2016-11-30" version="1">MGFVESVLAGGLISLGLDHEVELKALLAFNKVLWIQNDYFAKYYCNPATIHDAKAISSDNSFATRLASPSNLLSMAIGIAVGALGVCHQFRRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N286</accession>
    <name>A0A1C7N286_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Ricin B lectin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_08837</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000719">
        <property type="protein sequence ID" value="OBZ83111.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N286"/>
    <dbReference type="STRING" id="101091.A0A1C7N286"/>
    <dbReference type="InParanoid" id="A0A1C7N286"/>
    <dbReference type="OrthoDB" id="9895617at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd23454">
        <property type="entry name" value="beta-trefoil_Ricin_GllA-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.80.10.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022234">
        <property type="entry name" value="DUF3759"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035992">
        <property type="entry name" value="Ricin_B-like_lectins"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37450">
        <property type="entry name" value="CIPC PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37450:SF1">
        <property type="entry name" value="CIPC PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12585">
        <property type="entry name" value="DUF3759"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50370">
        <property type="entry name" value="Ricin B-like lectins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="269"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="272"/>
            <end position="282"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ83111.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="308" mass="35424" checksum="4FDAF97A47CACCF3" modified="2016-11-30" version="1">MTIETEGFPNGYFYIISKMNGLAIDIDTTEPPKAGTKLITATKKESKPERDTQLWIHQNGFLTNKFSGLVMDIGRSKKFIDIFTGNLHLYVDVMKEEESANDQRFGYDHENGYIYTLFEPNQVLDIRKKEAEEGATIMLYEKKDVIEEGINQLWDLQLADPPKVIDSSDEEEDDGKRARFSAWFGSWFGWDNKNNDALQERDLEKAHEKVYEKKKSHLSYEIIAGAVAVQAVKMYLDQQEANGEEVHFKGAKEVIAGFAAKEMVKMFMERGTDDDDDDDDEEQKEKKQTLLQKMATSAAVNYFDKKYK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N2Z0</accession>
    <name>A0A1C7N2Z0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_08462</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000653">
        <property type="protein sequence ID" value="OBZ83493.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N2Z0"/>
    <dbReference type="STRING" id="101091.A0A1C7N2Z0"/>
    <dbReference type="InParanoid" id="A0A1C7N2Z0"/>
    <dbReference type="OrthoDB" id="5971719at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="31"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="31"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="76"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="144"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="163"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="175"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="222"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="256"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="317"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ83493.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="338" mass="36395" checksum="A89C33A84F51B2CB" modified="2016-11-30" version="1" fragment="single">QKQARDQQKQLEELQKLTQQQLELQKQLAMQTGTQQQQQQQQQKMMQIQSQQQQLQQQLAQQPQQLQPSFAPILSPTATTGFESQPTGFQGMQPTGFQGAQPTGFQGAQPTGFQGTQPTGFSHISPTQPYQAAPAGRPRPTPSHRLSTDPSLGQWQPPSQQLVQTNVSSSNTSSPWQGLQPQMTGFPSQSQPIGGYQQPSSASLPPPLNPNASSASAAGQQGEFNSTGVGLQRAQTISAQPTGRHWGNATPANPFGSPTLSPLQAQMTGVQFSTPSPQAFHQSPLQSHQPTGYMQPQMTGFPQQQAPPPPPSAGGSNIFTPQGSMQYGQSAFPTQRPW</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N484</accession>
    <name>A0A1C7N484_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Histidine--tRNA ligase, mitochondrial</fullName>
            <ecNumber evidence="3">6.1.1.21</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Histidyl-tRNA synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="17" type="primary">hts1_1</name>
        <name evidence="17" type="ORF">A0J61_08037</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Catalyzes the aminoacylation of histidyl-tRNA in both the cytoplasm and the mitochondrion.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>tRNA(His) + L-histidine + ATP = L-histidyl-tRNA(His) + AMP + diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17313"/>
            <dbReference type="Rhea" id="RHEA-COMP:9665"/>
            <dbReference type="Rhea" id="RHEA-COMP:9689"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57595"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78527"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.21"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the class-II aminoacyl-tRNA synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.21" evidence="3"/>
    <dbReference type="EMBL" id="LUGH01000584">
        <property type="protein sequence ID" value="OBZ83913.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N484"/>
    <dbReference type="FunCoup" id="A0A1C7N484">
        <property type="interactions" value="620"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N484"/>
    <dbReference type="InParanoid" id="A0A1C7N484"/>
    <dbReference type="OrthoDB" id="1906957at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004821">
        <property type="term" value="F:histidine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006427">
        <property type="term" value="P:histidyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032543">
        <property type="term" value="P:mitochondrial translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00773">
        <property type="entry name" value="HisRS-like_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00859">
        <property type="entry name" value="HisRS_anticodon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.800:FF:000015">
        <property type="entry name" value="Histidyl-tRNA synthetase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.930.10:FF:000021">
        <property type="entry name" value="Probable histidine--tRNA ligase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.800">
        <property type="entry name" value="Anticodon-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="entry name" value="Bira Bifunctional Protein, Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006195">
        <property type="entry name" value="aa-tRNA-synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004154">
        <property type="entry name" value="Anticodon-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036621">
        <property type="entry name" value="Anticodon-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015807">
        <property type="entry name" value="His-tRNA-ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041715">
        <property type="entry name" value="HisRS-like_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004516">
        <property type="entry name" value="HisRS/HisZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033656">
        <property type="entry name" value="HisRS_anticodon"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00442">
        <property type="entry name" value="hisS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11476:SF7">
        <property type="entry name" value="HISTIDINE--TRNA LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11476">
        <property type="entry name" value="HISTIDYL-TRNA SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03129">
        <property type="entry name" value="HGTP_anticodon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13393">
        <property type="entry name" value="tRNA-synt_His"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001549">
        <property type="entry name" value="His-tRNA_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52954">
        <property type="entry name" value="Class II aaRS ABD-related"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="Class II aaRS and biotin synthetases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50862">
        <property type="entry name" value="AA_TRNA_LIGASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 17" id="KW-0436">Ligase</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aminoacyl-transfer RNA synthetases class-II family profile" evidence="16">
        <location>
            <begin position="53"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="29"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <begin position="122"/>
            <end position="124"/>
        </location>
        <ligand>
            <name>L-histidine</name>
            <dbReference type="ChEBI" id="CHEBI:57595"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="152"/>
        </location>
        <ligand>
            <name>L-histidine</name>
            <dbReference type="ChEBI" id="CHEBI:57595"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="168"/>
        </location>
        <ligand>
            <name>L-histidine</name>
            <dbReference type="ChEBI" id="CHEBI:57595"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="172"/>
        </location>
        <ligand>
            <name>L-histidine</name>
            <dbReference type="ChEBI" id="CHEBI:57595"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="323"/>
        </location>
        <ligand>
            <name>L-histidine</name>
            <dbReference type="ChEBI" id="CHEBI:57595"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <begin position="327"/>
            <end position="328"/>
        </location>
        <ligand>
            <name>L-histidine</name>
            <dbReference type="ChEBI" id="CHEBI:57595"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012815"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00030619"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00047639"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00058343"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00067413"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PIRSR" id="PIRSR001549-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="OBZ83913.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="504" mass="56878" checksum="AF60054E7C7AA9E3" modified="2016-11-30" version="1">MLSSSMLRRICLVPTVRSSRPAWIATCRSMSTKPESSQENKKPAQFQLKTPKGTRDYNEKEMAIRQSLFNTITRIFERHGGVTIDTPVFEMRDILSGKYGEDSKLIYDLADQGGDACSLRYDLTVPFARYLAMQGKKDAQQMKRYQIAKVYRRDQPIMTKGRLREFYQCDFDIAGTFDPLIPDAEVLKVLCDTLDAVQVPFSIKLNHRKILDGLFEVCGVPTDKIRTISSAVDKLDKLPWEDVKREMTAEKGLDPSVADRIGSYIQRFQNQPTHDLLIQLEQDAALMSHAGASQGLADLKLLFEFLEIYQVKDRVKLDLSLARGLDYYTGIIYEAVTDKSEGVGSIAAGGRYDDLVGMFSGTNKTGKPKTIPCVGVSIGVERLFSILMSRQKNEIKSSKTQVYVISVGDGLLKERMQLVRELWDAGIQASFMQKNKPKLERQWVACEKEQIPFAVIIGQDELEKGQVRIKDMRSKNESQGGGSLLSRQDMISKLKQKIKESSSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N4Q2</accession>
    <name>A0A1C7N4Q2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Transmembrane protein 42</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_07908</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000565">
        <property type="protein sequence ID" value="OBZ84041.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N4Q2"/>
    <dbReference type="STRING" id="101091.A0A1C7N4Q2"/>
    <dbReference type="InParanoid" id="A0A1C7N4Q2"/>
    <dbReference type="OrthoDB" id="5854584at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3730.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037185">
        <property type="entry name" value="EmrE-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039632">
        <property type="entry name" value="TMEM42"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31965">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 42"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31965:SF1">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 42"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103481">
        <property type="entry name" value="Multidrug resistance efflux transporter EmrE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="55"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="89"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="115"/>
            <end position="132"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ84041.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="144" mass="15819" checksum="9687CB4B0DD9FDEE" modified="2016-11-30" version="1">MTQSSTSYIPFAIISGAFAALSSVFAKLFSDERTTVFYTDIMSAYQLVPEKTALILIRGICFGLIFACNSIMWTTFTKALNRSPSSVQVSIVNGAVNFSTSAILGYVVFQEPLALRWWIGASFILAGTILLSQSQQKHSKQKDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N532</accession>
    <name>A0A1C7N532_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_07731</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000539">
        <property type="protein sequence ID" value="OBZ84222.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N532"/>
    <dbReference type="STRING" id="101091.A0A1C7N532"/>
    <dbReference type="InParanoid" id="A0A1C7N532"/>
    <dbReference type="OrthoDB" id="1923159at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="588"/>
            <end position="631"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="618"/>
            <end position="631"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ84222.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="631" mass="72797" checksum="07BD4088A4C9398D" modified="2016-11-30" version="1">MSEEEEDVTMEEIISTDIKESTPVTVVNDAAFKSTSVALIEKLLQFSMMDIFMTHVSRLDPTMETAELEHCTIEKKLLYSRHPRDMQDMEATKRSYHAMELLSGTTANHLWVQNAKFYDIVHHLFNVFLPNSHGNLNHFFRIFQHLVRRHPCDMLDVVILRNHAGILFHSMLPYLTQPPIMESLLHLIFVRDLNAETKEQRLASYEQLSALGLLEWLVKVTQLKQFPDYVEAAQEFLIRLIEEASQVDYGDILFKALRTEKGVEIVEMMVKQVTQQSTSRERMITVLRLFVKNGMLTTRASSQPVQGPLYFVSLRCQDLLMPHIPNFCHLFTHDRKDLNTKDQPLTLADLDLLDIIYHILYNANEKTELLVSIPSTFWRILVNQFFERATSTIYHTLFYRLVCLVLAINHEPTLVVLVRKQGLITRLIDAYTHKDLRGYILLILNQLRLMADARHSALIRRIIKEHPRYQAFLPTLRQDTLAQTQPIYTWKLEACPRPPAHLGPSPPIQSVHFSPYAGTIPLMTHMDDHHDNDDTTTGIDLGSDFAFCLGFKETEHGIETPYEYLSRRNSEHSMSSYASHPSIQESGFPMDGLWGESLTADIDEPEQTVGHSISTSKPSKKKKKRKHKGRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N634</accession>
    <name>A0A1C7N634_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">RGS domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_07844</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000555">
        <property type="protein sequence ID" value="OBZ84106.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N634"/>
    <dbReference type="STRING" id="101091.A0A1C7N634"/>
    <dbReference type="InParanoid" id="A0A1C7N634"/>
    <dbReference type="OrthoDB" id="10266999at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd07440">
        <property type="entry name" value="RGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.167.10">
        <property type="entry name" value="Regulator of G-protein Signalling 4, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016137">
        <property type="entry name" value="RGS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036305">
        <property type="entry name" value="RGS_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044926">
        <property type="entry name" value="RGS_subdomain_2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10845">
        <property type="entry name" value="REGULATOR OF G PROTEIN SIGNALING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10845:SF267">
        <property type="entry name" value="REGULATOR OF G PROTEIN SIGNALING DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_6G06860)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00615">
        <property type="entry name" value="RGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00315">
        <property type="entry name" value="RGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48097">
        <property type="entry name" value="Regulator of G-protein signaling, RGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50132">
        <property type="entry name" value="RGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RGS" evidence="1">
        <location>
            <begin position="27"/>
            <end position="123"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50132"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ84106.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="243" mass="27963" checksum="29FA6E0EC466E867" modified="2016-11-30" version="1">MMMSADLSVLSLESVLDDRNSDLFKEFSEYLHHSYCIENLSFWIAVQDYTKGCTQYRKELSKTIVDLHIRPNASQEINIPCEMREAILDLYSQENYHCHLFDEAAEAILELMRVNSFLPWTTSSHLISSSSSIASSSSLENRRSWSIKKEKLLHSTLSDAKWLVKLRQSTSSNTSSCPSSIDSFECPCLDDANQVSVSSVSRSGSRYRSMLKRVKQSFQFHFQSENKVSHPNTSESYWRKTQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N639</accession>
    <name>A0A1C7N639_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">PHO85 cyclin-1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">PCL1_3</name>
        <name evidence="2" type="ORF">A0J61_07449</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000502">
        <property type="protein sequence ID" value="OBZ84507.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N639"/>
    <dbReference type="STRING" id="101091.A0A1C7N639"/>
    <dbReference type="InParanoid" id="A0A1C7N639"/>
    <dbReference type="OrthoDB" id="10250320at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000307">
        <property type="term" value="C:cyclin-dependent protein kinase holoenzyme complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016538">
        <property type="term" value="F:cyclin-dependent protein serine/threonine kinase regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019901">
        <property type="term" value="F:protein kinase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd20557">
        <property type="entry name" value="CYCLIN_ScPCL1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.10">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036915">
        <property type="entry name" value="Cyclin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006671">
        <property type="entry name" value="Cyclin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013922">
        <property type="entry name" value="Cyclin_PHO80-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15615">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15615:SF108">
        <property type="entry name" value="PROTEIN CNPPD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00134">
        <property type="entry name" value="Cyclin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47954">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cyclin N-terminal" evidence="1">
        <location>
            <begin position="50"/>
            <end position="157"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ84507.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="180" mass="21025" checksum="A065E274AADF8969" modified="2016-11-30" version="1">MIEVSTLNTDVDFHSGLSHNLSLRVRHGTDHLILYTAYNVKSLLECSRERTSYQQRLLPTLSVFVRHLFHHCQLTPTLLVVTLIYLQRLKEGLPRHSKGEFDTPYKIFIAAVVLATKFIEDKSTITQSIYRFISPLYKARDINEMERSFLGVVKYNLFVDLSEVHEFVKNHKDLLEFDLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-06-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N6H2</accession>
    <name>A0A1C7N6H2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_07194</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000473">
        <property type="protein sequence ID" value="OBZ84755.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N6H2"/>
    <dbReference type="InParanoid" id="A0A1C7N6H2"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ84755.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="117" mass="13106" checksum="F9877CE9BFD96FD5" modified="2016-11-30" version="1">MRTDSLHSIQLPNPYRIKQLFASKDALPAPIHQSDLSRIYSYLLYANHAPDFVQSRAALYFENDTQAITSAIQIGLIYTEYTLERPLSQLHGSLSSRVTLKEGRDKQAIIGGVVLST</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N6P0</accession>
    <name>A0A1C7N6P0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_07181</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000471">
        <property type="protein sequence ID" value="OBZ84770.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N6P0"/>
    <dbReference type="STRING" id="101091.A0A1C7N6P0"/>
    <dbReference type="InParanoid" id="A0A1C7N6P0"/>
    <dbReference type="OrthoDB" id="2213594at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="51"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="51"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ84770.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="93" mass="10347" checksum="83A30EB7B15631CC" modified="2016-11-30" version="1">MHIRRNFGRFKRGESAKVELSNNRGITVTIVEAICEKGMIDLTLRKSKAVQRKVASNKKRKRSDGASDGVAATVKSGTRSEHFLEFIEGISIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N6Q1</accession>
    <name>A0A1C7N6Q1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Low-affinity potassium transport protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">TRK2_0</name>
        <name evidence="8" type="ORF">A0J61_07218</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000477">
        <property type="protein sequence ID" value="OBZ84721.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N6Q1"/>
    <dbReference type="FunCoup" id="A0A1C7N6Q1">
        <property type="interactions" value="88"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N6Q1"/>
    <dbReference type="InParanoid" id="A0A1C7N6Q1"/>
    <dbReference type="OrthoDB" id="9999863at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140107">
        <property type="term" value="F:high-affinity potassium ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030007">
        <property type="term" value="P:intracellular potassium ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990573">
        <property type="term" value="P:potassium ion import across plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003445">
        <property type="entry name" value="Cat_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051143">
        <property type="entry name" value="TrkH_K-transport"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31064:SF30">
        <property type="entry name" value="HIGH-AFFINITY POTASSIUM TRANSPORT PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31064">
        <property type="entry name" value="POTASSIUM TRANSPORT PROTEIN DDB_G0292412-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02386">
        <property type="entry name" value="TrkH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81324">
        <property type="entry name" value="Voltage-gated potassium channels"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0406">Ion transport</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="20"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="74"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="400"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="481"/>
            <end position="509"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="545"/>
            <end position="571"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="700"/>
            <end position="721"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OBZ84721.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="828" mass="94779" checksum="47B1C6B6766703CC" modified="2016-11-30" version="1">MFSIRLWDFLKHVYHEKIHFLQLHYIYILSLSLLLSCCFYIESDTHWSYIDALFMATTSATNTGLGTIDMSQLSYWQLVVMCLGSFLGSHIIISIIIVYTRRHYFSRRFEDILIFNHTQQLREANKRKFEKAVQELDKQQQKRSLDQRLSFLSTRSLSSRKEEGNEETMSATLASTLKRNLFTSRPFSSTSLTSLDLKPLSSTKRNASLDTMHFTKSGTKNLKQMEHSRSSPNVNTDLDAYSRPKEWKEPDFYTDDDQHKDTTINRFNAPNEAGSEKGSIEIVIQRPSLDSLRNHNETNAIESASAHNQAIAFAENIDQQRMIARRRLEQDRQFEEVLQQIAGEADINMAPYSRRSIDQTTTVIESENDEEILRIMKEPIEKSQLTRQQRYRLGGAEYRALELLTIIVPCFYFFFVVGFGFLIRIYIASSTFAQEVLKTSTIKGVPIDSWFFSFFLSLSSFNNLGLSVLDTSMISFQSSPCILILCMILILAGNTAYAIFLRCAIWILYKLTPKTYVMRREALLYLLNNPRRCYTTLFPATQTKWLLIVLIGITTVEFVCFVALNFSLPVLQHINWDMRILDGLFQSVATRNAGYSVVDLNSLNPAIQIVFIVAMYISVYPVAISMRNSNVYQERALGIYKGIDDDDMYDDSHQMKGFHSDHRLKRHSTMTSIVVNSKKILQGPDFFVMTQIQRQLTSEICWVICCIFAICVIEADAIAAASPISISSVIYECVSAFGNVGASTGYPNTTASQAQQYHPLSKLILIVLMYRGRHRGLPATIDRAVLLPSEQLEEKELEDDTFKRRNTSFSINDGLGASFVFYDRSRTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N729</accession>
    <name>A0A1C7N729_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="10">DNA-directed RNA polymerase I subunit rpa43</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">rpa43</name>
        <name evidence="10" type="ORF">A0J61_07009</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the eukaryotic RPA43 RNA polymerase subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000452">
        <property type="protein sequence ID" value="OBZ84940.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N729"/>
    <dbReference type="SMR" id="A0A1C7N729"/>
    <dbReference type="STRING" id="101091.A0A1C7N729"/>
    <dbReference type="InParanoid" id="A0A1C7N729"/>
    <dbReference type="OrthoDB" id="10250504at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005736">
        <property type="term" value="C:RNA polymerase I complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006362">
        <property type="term" value="P:transcription elongation by RNA polymerase I"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd04328">
        <property type="entry name" value="RNAP_I_Rpa43_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.1060">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.120">
        <property type="entry name" value="RNA polymerase Rpb7-like, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036898">
        <property type="entry name" value="RNA_pol_Rpb7-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041901">
        <property type="entry name" value="RNAP_I_Rpa43_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041178">
        <property type="entry name" value="RPA43_OB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045113">
        <property type="entry name" value="Rpb7-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005576">
        <property type="entry name" value="Rpb7-like_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12709:SF5">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE I SUBUNIT RPA43"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12709">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE II, III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17875">
        <property type="entry name" value="RPA43_OB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03876">
        <property type="entry name" value="SHS2_Rpb7-N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 10" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="4" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <feature type="domain" description="RNA polymerase Rpb7-like N-terminal" evidence="8">
        <location>
            <begin position="59"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="domain" description="RPA43 OB" evidence="9">
        <location>
            <begin position="129"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="179"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="187"/>
            <end position="198"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005930"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF03876"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF17875"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OBZ84940.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="246" mass="27501" checksum="2A290A2423045019" modified="2016-11-30" version="1">MSIVEKKRKHKDSSEKSSKKKQKKSSTKIVAPVLPATSTLTTTSLPTVSSSFSEVVVKLYLHLAPMWSGKTMEGVNEQLNAFLMKYLPEVDGIVLAHSDVKFVTDKGKILYDSPFFHFFVTVKFLVWKPKRGSKLVGRINLQSEDHIGLLIYGTFNASIPKSRIPSSVYEWKVNEEEEPVEIKEEKDESEQDDEAEAAPEERTRTQYGEWINKSTGASIGGEDGILEFSVVDIIEANDILTVTGSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N780</accession>
    <name>A0A1C7N780_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">BRCT domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_07487</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000507">
        <property type="protein sequence ID" value="OBZ84459.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N780"/>
    <dbReference type="STRING" id="101091.A0A1C7N780"/>
    <dbReference type="InParanoid" id="A0A1C7N780"/>
    <dbReference type="OrthoDB" id="2222735at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10190">
        <property type="entry name" value="BRCT domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001357">
        <property type="entry name" value="BRCT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036420">
        <property type="entry name" value="BRCT_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00533">
        <property type="entry name" value="BRCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00292">
        <property type="entry name" value="BRCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52113">
        <property type="entry name" value="BRCT domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50172">
        <property type="entry name" value="BRCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BRCT" evidence="2">
        <location>
            <begin position="53"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="217"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="256"/>
            <end position="275"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ84459.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="302" mass="35091" checksum="6155BA521A040AB4" modified="2016-11-30" version="1">MENVSLVQHNNFRFTARINQPKRTIKKPRQIRQKRPKLSFPNPTLLPELDLNDLPPVLKNYVILIQSNPRSQLQSLAEGLGATVKQEMEKAVTHVVITKETSKEQRLIHAYEKKSIICVSPKWLLTCYSTQQYHSPLSFPVEINDEQYILNDVHVVENPFEADYIDFDAIEQTKAVEGQLRMDQFLIPPPQPTQEEEEEAPLMLSQEVAEQEYFYNQDCPSSMDPSQQKKRKEEAEKRNLQAQRYIEQRQKETAAKPSTSELTIRSLASHNQQSDQLFGQERLRVWYGEQAKSAVKSKRKRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N7A8</accession>
    <name>A0A1C7N7A8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Nitrogen regulatory protein areA GATA-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_06925</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000442">
        <property type="protein sequence ID" value="OBZ85020.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N7A8"/>
    <dbReference type="STRING" id="101091.A0A1C7N7A8"/>
    <dbReference type="InParanoid" id="A0A1C7N7A8"/>
    <dbReference type="OrthoDB" id="515401at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031930">
        <property type="term" value="P:mitochondria-nucleus signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000122">
        <property type="term" value="P:negative regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006808">
        <property type="term" value="P:regulation of nitrogen utilization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013860">
        <property type="entry name" value="AreA_GATA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053043">
        <property type="entry name" value="Ras-cAMP_regulatory"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28014">
        <property type="entry name" value="NEGATIVE REGULATOR OF RAS-CAMP PATHWAY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28014:SF1">
        <property type="entry name" value="NEGATIVE REGULATOR OF RAS-CAMP PATHWAY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08550">
        <property type="entry name" value="GATA_AreA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nitrogen regulatory protein areA GATA-like" evidence="2">
        <location>
            <begin position="28"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="120"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="120"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="130"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="141"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="170"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="201"/>
            <end position="223"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF08550"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ85020.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="265" mass="30262" checksum="D155786D43F51AFD" modified="2016-11-30" version="1">MSSTQPSLLSVSCKDLDSIGQADKLATLWIAFNKSKNYIENGQRLENMSWRLWQYQRQPTNKIDNSTIKRFITSVLLSPAAVHDADSHEVAQEKCYDDEGNKELSCSSSIIIVDHKYQPATASLSPPQDNQTTTRNNIIITEDEEDEDYYLSDDDLYDEDDEEEEQLSDINTNFVRDFQKTQPRPTTPRRSLLSDLFSRVSSPPSLLSNSTSSFTSTNTNNSSMEDHQHAQQHSSFSKNHAALSILRENDSTPNETRWRESFHGW</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N7K3</accession>
    <name>A0A1C7N7K3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_06923</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000441">
        <property type="protein sequence ID" value="OBZ85027.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N7K3"/>
    <dbReference type="STRING" id="101091.A0A1C7N7K3"/>
    <dbReference type="InParanoid" id="A0A1C7N7K3"/>
    <dbReference type="OrthoDB" id="2257766at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ85027.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="113" mass="12688" checksum="A95EE4C5F06E8FC1" modified="2016-11-30" version="1" fragment="single">AAASTAAILKGATFQEVKTHGNWSQNSSTVEDYYFRPPNQHEAGRIMTERIFQSTENQTTSEVGVSHTAIVVGTTHNGQVGETKTEDVVTTRPWTMPWHWFSRPKKVIEKLQT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N7K9</accession>
    <name>A0A1C7N7K9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Protein diaphanous 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">DIAPH1</name>
        <name evidence="9" type="ORF">A0J61_07342</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the formin homology family. BNI1 subfamily.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the formin homology family. Diaphanous subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000489">
        <property type="protein sequence ID" value="OBZ84609.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="FunCoup" id="A0A1C7N7K9">
        <property type="interactions" value="54"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N7K9"/>
    <dbReference type="InParanoid" id="A0A1C7N7K9"/>
    <dbReference type="OrthoDB" id="1104827at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015629">
        <property type="term" value="C:actin cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005938">
        <property type="term" value="C:cell cortex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032153">
        <property type="term" value="C:cell division site"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043332">
        <property type="term" value="C:mating projection tip"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003779">
        <property type="term" value="F:actin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031267">
        <property type="term" value="F:small GTPase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051017">
        <property type="term" value="P:actin filament bundle assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051016">
        <property type="term" value="P:barbed-end actin filament capping"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1903475">
        <property type="term" value="P:mitotic actomyosin contractile ring assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.630">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.30.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.20.40">
        <property type="entry name" value="Formin, diaphanous GTPase-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.2220">
        <property type="entry name" value="Formin, FH2 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.150">
        <property type="entry name" value="Formin, FH3 diaphanous domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051661">
        <property type="entry name" value="Actin_filament_regulator"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014767">
        <property type="entry name" value="DAD_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044933">
        <property type="entry name" value="DIA_GBD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015425">
        <property type="entry name" value="FH2_Formin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042201">
        <property type="entry name" value="FH2_Formin_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010472">
        <property type="entry name" value="FH3_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014768">
        <property type="entry name" value="GBD/FH3_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010473">
        <property type="entry name" value="GTPase-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47102">
        <property type="entry name" value="PROTEIN BNI1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47102:SF2">
        <property type="entry name" value="PROTEIN BNI1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06367">
        <property type="entry name" value="Drf_FH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06371">
        <property type="entry name" value="Drf_GBD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02181">
        <property type="entry name" value="FH2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01139">
        <property type="entry name" value="Drf_FH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01140">
        <property type="entry name" value="Drf_GBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00498">
        <property type="entry name" value="FH2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101447">
        <property type="entry name" value="Formin homology 2 domain (FH2 domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51231">
        <property type="entry name" value="DAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51444">
        <property type="entry name" value="FH2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51232">
        <property type="entry name" value="GBD_FH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GBD/FH3" evidence="7">
        <location>
            <begin position="45"/>
            <end position="517"/>
        </location>
    </feature>
    <feature type="domain" description="FH2" evidence="8">
        <location>
            <begin position="817"/>
            <end position="1232"/>
        </location>
    </feature>
    <feature type="domain" description="DAD" evidence="6">
        <location>
            <begin position="1266"/>
            <end position="1298"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="640"/>
            <end position="817"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1218"/>
            <end position="1324"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="541"/>
            <end position="578"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="670"/>
            <end position="683"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="685"/>
            <end position="699"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="701"/>
            <end position="714"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="716"/>
            <end position="813"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="1218"/>
            <end position="1235"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="1262"/>
            <end position="1272"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="1308"/>
            <end position="1324"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008214"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00037935"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51231"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51232"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51444"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OBZ84609.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="1324" mass="148710" checksum="7D8989973D15617B" modified="2016-11-30" version="1">MSDFFGSFRRKKNTPISPGPSSPRSSMDASSRRSHGPNDVSTDEPMPNSDQQIDDLFDQMLSRRGLDEEKKKPLKASLDYKTKWAMVVQDRKAEQVVSGRKTTNDQEEDETAQPLISVLSDLAGEMWSATRDSTARHIERHSYRHSQMGPIGRRATDANQASAPVINSTSVAYEGVLPTDKNSPEFYIRKFMEADLRAVTPALADNLAVSLRTRPLDWVIRFTDLKGLRVVTNGLAVLNKKPDAERKGQALELEYGLIKCIKVLINARWGAREAILNPDYIHSMVFSIGCPQWQARKTICDILLFLCHCDVPLGHNIVMQGFELYRQHRQEFGIFDAWIKDFEHALDGTHRVGRSNSIDEYQKLNVFVPPDSHLVEYCLSNLGLINALVYIPTEVNDRVYLRSQLKMSGLERIFSKLEKLDDPSLFDQMAKYRRRAESDLDEAFGDEISMYTEVSQPNELLELVLDNISDAPNALEFLLQTFRSMLLIKGSPDRKAHFHQAISEIVSNIVMDRREGVSVEELGSSAFGISVNSMVGRFNELDRLQELARTAEEDREMALRLGAENKALKDEIQTLRKATHRDNEGQHNYKLENIALRALQNQSNKTIAMLQERLKEKTDDLDEVSSIASSPPSIVVGEQWKLSGRRPDNTLPLPSLSKSAELAKAKESPIPTSEEQDNSTNNDAIPPPPPPPPPPPPPNLNFLSAKTAMTGSNSGAPPPPPPPPPPPPPPGGMSGPPPPPPPGGSGAPPPPPPPPPPPPGGPGAPPPPPPPPPPPPPGGPGAPPPPPPPPPGGPGAPPPPPPPGGPNLPPVPTGPARKQLRHYPQVKLKNLQWQKLDARGVEKTVWKLEDVDEDQIEDELDKNGVFEKIEELFPAKVNNFFEKRLKAKVEEKKDAVKFLSKEKTRNINLAVLPKVKQYNSYAEVRLEIMKINDEICTETFLGNLLAYVPSKDDDLKLMEKYLTGEPEACEELDFPEQFTIEMYRMYRYEPRIQFMLFRVQFWEKLEQLQRNMTIVLQVSDVLKNSKYLKNLLCLILVLGNFMNASSLQGGAFGMRISSINKLVDTKASNISSLTLLHVVTGVVRRQFPQLLGFLEDLKEIEQAARVTASMNDMIQQYTEMRKGLKDLDNELETQWKDAEINEEEDKFRSVMTTYKEEASLRFQDLQTLYINMDAAWKDVMVYYGENPKVMRPDDFFGTFARFVVTWKAASLAEEKMAMKQEREEKRKREEEERKERARLKKEKAEAALKAKRGSVQGINTDADGKGESDRCMMDNLLEQLRTGEVEVRTTSRRSRRNKERKEEDDDSANALSAADLLKSLASEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N7T9</accession>
    <name>A0A1C7N7T9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Sphingomyelin phosphodiesterase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">Smpd1</name>
        <name evidence="14" type="ORF">A0J61_06914</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Converts sphingomyelin to ceramide.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="10">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="10">Binds 2 Zn(2+) ions per subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the acid sphingomyelinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000440">
        <property type="protein sequence ID" value="OBZ85038.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N7T9"/>
    <dbReference type="STRING" id="101091.A0A1C7N7T9"/>
    <dbReference type="InParanoid" id="A0A1C7N7T9"/>
    <dbReference type="OrthoDB" id="282973at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016798">
        <property type="term" value="F:hydrolase activity, acting on glycosyl bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004767">
        <property type="term" value="F:sphingomyelin phosphodiesterase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006685">
        <property type="term" value="P:sphingomyelin catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00842">
        <property type="entry name" value="MPP_ASMase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045473">
        <property type="entry name" value="ASM_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041805">
        <property type="entry name" value="ASMase/PPN1_MPP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011160">
        <property type="entry name" value="Sphingomy_PDE"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10340">
        <property type="entry name" value="SPHINGOMYELIN PHOSPHODIESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10340:SF34">
        <property type="entry name" value="SPHINGOMYELIN PHOSPHODIESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19272">
        <property type="entry name" value="ASMase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000948">
        <property type="entry name" value="Sphingomy_PDE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="Metallo-dependent phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="8" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="9" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="6 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0964">Secreted</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <keyword evidence="7 10" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Calcineurin-like phosphoesterase" evidence="12">
        <location>
            <begin position="74"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="domain" description="Sphingomyelin phosphodiesterase C-terminal" evidence="13">
        <location>
            <begin position="377"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="80"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="82"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="152"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="152"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="198"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="316"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="351"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="353"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="disulfide bond" evidence="11">
        <location>
            <begin position="95"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="11">
        <location>
            <begin position="101"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="11">
        <location>
            <begin position="274"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="11">
        <location>
            <begin position="482"/>
            <end position="486"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRNR" id="PIRNR000948"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR000948-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR000948-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF00149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF19272"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="OBZ85038.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="534" mass="61794" checksum="3F908E3CBFCADCD2" modified="2016-11-30" version="1">MVDDQVCEGMVREQGPVIRRVLRTMDVGGRDGHLACASVLNACPYPKIIPWTVPFPKPKPKYTYRHKRNNKTITVLHLSDWHVDPQYQEGAETECSKPICCRKEYTDYQNISSKASPWGSFNCDSSIHLIQSMLDYIPKISPKTSFGILTGDIPPHEVWETLPVKKTQAIQEASYTLLHSYFDSPLFIGAKLYPAIGNHEAAPTNLFPLIDSNLPRDDRRRYDMSMEWLYSTLQSSWEGWLPSQHLPSIHKNSGSYISHPYPGLKLISINTNFCYNLNWWMYEQPSRRDPNGILTWLVAQLQKSEDIRERVWIIGHTPPGDDSCFHDYSNYYYQIIERYAPHVIAGQFFGHTHRDEIQLFYRHNATQKAKDAISIGYLAPSITPFPDMNPGFRTYTVDTGTFEVVDSHTYIADLNQSIDWEHEPNWHREYSAKEYYGSNTNSFAPLSPAWWHQFTEEMEHDDKKFDLYWLHRYKSSPSIPPCDHQCRINAVCNIRAGKSELRCDYDPSEATPRAVILDRKDKNACGLQLLKRSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N7U4</accession>
    <name>A0A1C7N7U4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Pinin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">Pnn</name>
        <name evidence="11" type="ORF">A0J61_06755</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the pinin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000423">
        <property type="protein sequence ID" value="OBZ85193.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N7U4"/>
    <dbReference type="STRING" id="101091.A0A1C7N7U4"/>
    <dbReference type="InParanoid" id="A0A1C7N7U4"/>
    <dbReference type="OrthoDB" id="330772at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071013">
        <property type="term" value="C:catalytic step 2 spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008380">
        <property type="term" value="P:RNA splicing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039853">
        <property type="entry name" value="Pinin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006786">
        <property type="entry name" value="Pinin_SDK_MemA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12707:SF0">
        <property type="entry name" value="PININ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12707">
        <property type="entry name" value="PINN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04696">
        <property type="entry name" value="Pinin_SDK_memA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="6" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="4" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Pinin/SDK/MemA protein" evidence="10">
        <location>
            <begin position="47"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="179"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="77"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="34"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="179"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="196"/>
            <end position="209"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010386"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF04696"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="OBZ85193.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="219" mass="25790" checksum="5EE95B45AAD7F30D" modified="2016-11-30" version="1">MVQSSIIVPESTTNVPSNKRRADNLDLDTSATSEEIKRPRLIDQDETGKKRNKRLFGTLLGTLSKFKDETEKDSEINKNRQAINNKLQEKLEQERKELQEKLKARKEEKMRLAEQKIQEEQRLLEEKKELSKILQNEKLAYFLKTTTQPTLYYLPQKLTDEMVETIELQKKEALTARIQFEERGEKSEGKRKHDDCSEEEDDPIQDDSEQYATNKKEEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N803</accession>
    <name>A0A1C7N803_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="12 14">Adenosine kinase</fullName>
            <shortName evidence="14">AK</shortName>
            <ecNumber evidence="4 14">2.7.1.20</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="14">Adenosine 5'-phosphotransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="16" type="primary">ADK1_1</name>
        <name evidence="16" type="ORF">A0J61_07187</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="14">ATP dependent phosphorylation of adenosine and other related nucleoside analogs to monophosphate derivatives.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11 14">
            <text>adenosine + ATP = AMP + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:20824"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16335"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.20"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 14">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2 14">Purine metabolism; AMP biosynthesis via salvage pathway; AMP from adenosine: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 14">Belongs to the carbohydrate kinase PfkB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.20" evidence="4 14"/>
    <dbReference type="EMBL" id="LUGH01000472">
        <property type="protein sequence ID" value="OBZ84766.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N803"/>
    <dbReference type="FunCoup" id="A0A1C7N803">
        <property type="interactions" value="554"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N803"/>
    <dbReference type="InParanoid" id="A0A1C7N803"/>
    <dbReference type="OrthoDB" id="432447at2759"/>
    <dbReference type="UniPathway" id="UPA00588">
        <property type="reaction ID" value="UER00659"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004001">
        <property type="term" value="F:adenosine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044209">
        <property type="term" value="P:AMP salvage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006144">
        <property type="term" value="P:purine nucleobase metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006166">
        <property type="term" value="P:purine ribonucleoside salvage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01168">
        <property type="entry name" value="adenosine_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.1190.20:FF:000076">
        <property type="entry name" value="Adenosine kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1190.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001805">
        <property type="entry name" value="Adenokinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002173">
        <property type="entry name" value="Carboh/pur_kinase_PfkB_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011611">
        <property type="entry name" value="PfkB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029056">
        <property type="entry name" value="Ribokinase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45769">
        <property type="entry name" value="ADENOSINE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45769:SF3">
        <property type="entry name" value="ADENOSINE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00294">
        <property type="entry name" value="PfkB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00989">
        <property type="entry name" value="ADENOKINASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53613">
        <property type="entry name" value="Ribokinase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00584">
        <property type="entry name" value="PFKB_KINASES_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 14" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8 14 16" id="KW-0418">Kinase</keyword>
    <keyword evidence="10 14" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7 14" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6 14" id="KW-0660">Purine salvage</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 14" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Carbohydrate kinase PfkB" evidence="15">
        <location>
            <begin position="23"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="13">
        <location>
            <position position="294"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010688"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022726"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00051362"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00068771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR601805-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU368116"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF00294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="OBZ84766.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="345" mass="37581" checksum="D7973E72CBBAA324" modified="2016-11-30" version="1">MPYTLLAMENPLLDIQCKPSQDLLEKYSLKANDAILADATHQPLYKEIVDNYEVAYVAGGAAQNTARGAQFFLPPNSTAYMGCVSDDKFGQIMGEAAKADGLYTNYEITHDAPTGTCAVLITGNNRSLVANLAAAEKFQASFLQKPENWKLVEEAKYYYMGSFFVTHDGGYQSALLVSQHAAENNKTFALNLSAPFLSQFFKERLDSVIKNTDILFGNEDEARTYSKVAGWNTDDVQEIAKKLSQLEKGNSKPRLVVITQGADATVTACGEESHVYPVIKVDGSEIVDTNGAGDAFCGGFMGLYAQGVTDAARCVQAGHYLANIVIKRVGPTYPPMEERTNIPSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N811</accession>
    <name>A0A1C7N811_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Membrane protein PTM1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">PTM1</name>
        <name evidence="12" type="ORF">A0J61_08476</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the LU7TM family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000656">
        <property type="protein sequence ID" value="OBZ83474.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N811"/>
    <dbReference type="FunCoup" id="A0A1C7N811">
        <property type="interactions" value="464"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N811"/>
    <dbReference type="InParanoid" id="A0A1C7N811"/>
    <dbReference type="OrthoDB" id="19932at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042147">
        <property type="term" value="P:retrograde transport, endosome to Golgi"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053937">
        <property type="entry name" value="GOST_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009637">
        <property type="entry name" value="GPR107/GPR108-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053938">
        <property type="entry name" value="PTM1-like_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21229:SF1">
        <property type="entry name" value="GH17801P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21229">
        <property type="entry name" value="LUNG SEVEN TRANSMEMBRANE RECEPTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06814">
        <property type="entry name" value="GOST_TM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21902">
        <property type="entry name" value="PTM1-like_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0732">Signal</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008889535" evidence="9">
        <location>
            <begin position="23"/>
            <end position="562"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="186"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="217"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="250"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="293"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="320"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="366"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="406"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="domain" description="PTM1-like N-terminal" evidence="11">
        <location>
            <begin position="35"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="domain" description="GOST seven transmembrane" evidence="10">
        <location>
            <begin position="184"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="457"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="511"/>
            <end position="562"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="538"/>
            <end position="549"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF06814"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF21902"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="OBZ83474.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="562" mass="63646" checksum="6B0CF218A50A604A" modified="2016-11-30" version="1">MTTKALLVSYVILSILFGALNAEEVYLSSNDYSATSCSGVWSKEAIPGGSQPYIKVSVGGESLGKVSMLIYEWNDFDKLGVYDKQLKETVYVCDQSAVSHKLCKSSEIGQFLTNVPSDQVNSTSVFTPTFEMGGNNTEMALYKINYTGYYCVALVPAGNSNSTRFEAWVEWRFPYGELPATDYPKLLLYGALACVYTAVGLFWAIQSYRNWSDILPVQHFLSATIFYLIVEMAFNFGFWEAYNQTGQTSYGLLALVALLNAGRTSMSFFMLLIVCMGYSVVKPTLGSAMKKCIILACTHFFFGVVYTLGTMLLSPETAGLLILLVIFPLSITMTIFYVWTLNSITSTIHSLELRKQHVKVTMYKRLYRLLLFSVIAVVTIFILNMFAFSGRMAIDWAAKNWKYRWVMLDGLLNILYFIVFFVIVILWRPTSNNARYGLMQISQDEEEALDLEERLRQVEDPENNVSNTGASRNRERHHLEDDTAIFELGGELTDEEEDHQPITKNVELADFQNKNTNKSGYHRSGRKEEQSALLHVDQDEEEDDDEHIDDSERAGLTKNARK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N9C4</accession>
    <name>A0A1C7N9C4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">DnaJ subfamily B member 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">DNAJB1</name>
        <name evidence="4" type="ORF">A0J61_06266</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000370">
        <property type="protein sequence ID" value="OBZ85687.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N9C4"/>
    <dbReference type="FunCoup" id="A0A1C7N9C4">
        <property type="interactions" value="325"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N9C4"/>
    <dbReference type="InParanoid" id="A0A1C7N9C4"/>
    <dbReference type="OrthoDB" id="10250354at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051087">
        <property type="term" value="F:protein-folding chaperone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006413">
        <property type="term" value="P:translational initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd10747">
        <property type="entry name" value="DnaJ_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.110:FF:000072">
        <property type="entry name" value="DnaJ family protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.260.20:FF:000002">
        <property type="entry name" value="Dnaj homolog subfamily b member"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.260.20:FF:000013">
        <property type="entry name" value="DnaJ subfamily B member 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.260.20">
        <property type="entry name" value="Urease metallochaperone UreE, N-terminal domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002939">
        <property type="entry name" value="DnaJ_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018253">
        <property type="entry name" value="DnaJ_domain_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051339">
        <property type="entry name" value="DnaJ_subfamily_B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008971">
        <property type="entry name" value="HSP40/DnaJ_pept-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24078:SF553">
        <property type="entry name" value="DNAJ HOMOLOG SUBFAMILY B MEMBER 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24078">
        <property type="entry name" value="DNAJ HOMOLOG SUBFAMILY C MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01556">
        <property type="entry name" value="DnaJ_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00625">
        <property type="entry name" value="JDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49493">
        <property type="entry name" value="HSP40/DnaJ peptide-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00636">
        <property type="entry name" value="DNAJ_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0143">Chaperone</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="J" evidence="3">
        <location>
            <begin position="4"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="73"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="161"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="306"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="84"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="306"/>
            <end position="315"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OBZ85687.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="360" mass="38611" checksum="10A1A4E2B99BBA31" modified="2016-11-30" version="1">MGKDYYSILGISRDADDDTIKKAYRKLALKWHPDRNKDKPEVANTKFQEIGEAYEVLSDKNKRAIFDQYGEEGLKGSAPPPGADGAGGFPGGGAAGGFPGGGTFHFSTNGGGFHPSDADDIFKHFFSSFGGSGGGMDDFGMGGMGGMGGMGGMPGGFSFGSSGGMPGSSRRFRTQPQEPEKPPAIKRSLPLSLEELYKGTVKRLKVTRKLRDGSTGRAVSTDKILSINVKAGWKAGTKIRFPGEGDELENGQTQDIEFIVEEKPHPVYKREGDNLRITVSLTLAEALTGFQKTIKTLDDRTLSVSNTKSVVQPGQESRVPNEGMPNSKTGKKGDLIITYEVKFPTSLSEQQKEGIKNLLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N9V4</accession>
    <name>A0A1C7N9V4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Kinesin-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="primary">KIF23</name>
        <name evidence="15" type="ORF">A0J61_06091</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
            <location evidence="1">Spindle</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="10 11">Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000351">
        <property type="protein sequence ID" value="OBZ85861.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N9V4"/>
    <dbReference type="FunCoup" id="A0A1C7N9V4">
        <property type="interactions" value="177"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N9V4"/>
    <dbReference type="InParanoid" id="A0A1C7N9V4"/>
    <dbReference type="OrthoDB" id="123929at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072686">
        <property type="term" value="C:mitotic spindle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005876">
        <property type="term" value="C:spindle microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008017">
        <property type="term" value="F:microtubule binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008574">
        <property type="term" value="F:plus-end-directed microtubule motor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007018">
        <property type="term" value="P:microtubule-based movement"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090307">
        <property type="term" value="P:mitotic spindle assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051231">
        <property type="term" value="P:spindle elongation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.850.10">
        <property type="entry name" value="Kinesin motor domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047149">
        <property type="entry name" value="KIF11-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019821">
        <property type="entry name" value="Kinesin_motor_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001752">
        <property type="entry name" value="Kinesin_motor_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036961">
        <property type="entry name" value="Kinesin_motor_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47970:SF29">
        <property type="entry name" value="KINESIN FAMILY MEMBER 20B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47970">
        <property type="entry name" value="KINESIN-LIKE PROTEIN KIF11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00225">
        <property type="entry name" value="Kinesin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00380">
        <property type="entry name" value="KINESINHEAVY"/>
    </dbReference>
    <dbReference type="SMART" id="SM00129">
        <property type="entry name" value="KISc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00411">
        <property type="entry name" value="KINESIN_MOTOR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50067">
        <property type="entry name" value="KINESIN_MOTOR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 10 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7 12" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="4 11" id="KW-0493">Microtubule</keyword>
    <keyword evidence="8 10 11" id="KW-0505">Motor protein</keyword>
    <keyword evidence="5 10 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Kinesin motor" evidence="14">
        <location>
            <begin position="68"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="500"/>
            <end position="530"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="665"/>
            <end position="704"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="852"/>
            <end position="872"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="12">
        <location>
            <begin position="626"/>
            <end position="660"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="12">
        <location>
            <begin position="813"/>
            <end position="847"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="22"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="13">
        <location>
            <begin position="509"/>
            <end position="530"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="667"/>
            <end position="686"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="687"/>
            <end position="704"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="852"/>
            <end position="865"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="160"/>
            <end position="167"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00283"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU000394"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50067"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="OBZ85861.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="872" mass="100707" checksum="7DE5D21DFB256A6A" modified="2016-11-30" version="1">MSNSQEPRTPTRGTPQRHRPRTGSTTPRSTIRISSHSKPHFKPPKAPDFSSLQSTNVNFFAYNPEKEPIKSYLRIRPRSQLHESDESMEPYLEILDDLEIAMTPPEDSNAYRTRNRAPERYKFTQVFTESVSQEHFFNKTTLPLIHDVLNGQNALIFAYGVTNSGKTYSIMGTQDHPGLLPRTLDVLFNSIDNYKSEAQVKPCMHSLVQTYTSPAEENRDSLKQWTLELPIHRDKTTLAIDPQFEYGIWVSFAEIYTEKIYDLLVSPDRLVRRKPLSLKYEYSSGHKYIAGLKEVKVKTIEEAYAVMLEGQRNRAQYSTLTNYRSSRSHSIFTVRIVRVPIDDNNYVIEDPMYATVSKLSIVDLAGSERYRNTLSSGQRLKEAGNINKSLMVLGQCMETLRLNQLKSSIGKRGAMVPYRHSKLTELFKSSFEGDGKAVMVVNVNPFDTGFDENSHVMKFAAVAKDVATWRKTHPKLELKDISAFVNKRLRVNSQEKKIYSGMDSIMKEQDEEEKAEDESDESDEEEEDPFVDNLISQLDDLRNKWMEAETRCSMMESDIRQQVMKDAEIKLKKMESFYLQSLKQYNQDNEDQINGRLIEEGDEGFVRLKMKQEVISQEIYTLQTHLDQHETTKNQLLEKINELERDKKKQHEQIKQLCNTVKERESTIQSLQTSHPITTHPSADQESTQKESTEPKEQEDQFSKFLDLRKRLRRSLFRGEEYSPDADVIMAQVEQFKGVTFELVKQTSMGKLMKLITERTFKEDPYHIQQRSKDLLKRYAKLSIPVLAPTPQTTGRGSMVVLSVNAGHEEELIMEMRGALSSLQEENTKLKQRLKSMQEGFRRLKEAIEQPAQQDLESILSSQPNEMDPMSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N9W0</accession>
    <name>A0A1C7N9W0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="1">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">dsk1_0</name>
        <name evidence="13" type="ORF">A0J61_06498</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the protein kinase superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="1"/>
    <dbReference type="EMBL" id="LUGH01000394">
        <property type="protein sequence ID" value="OBZ85449.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N9W0"/>
    <dbReference type="STRING" id="101091.A0A1C7N9W0"/>
    <dbReference type="InParanoid" id="A0A1C7N9W0"/>
    <dbReference type="OrthoDB" id="2649at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050684">
        <property type="term" value="P:regulation of mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000245">
        <property type="term" value="P:spliceosomal complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000770">
        <property type="entry name" value="SRSF protein kinase 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000275">
        <property type="entry name" value="SRSF protein kinase 2 isoform X3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051334">
        <property type="entry name" value="SRPK"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47634">
        <property type="entry name" value="PROTEIN KINASE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47634:SF9">
        <property type="entry name" value="PROTEIN KINASE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 13" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 9 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 10" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="12">
        <location>
            <begin position="48"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="213"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="213"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="11">
        <location>
            <begin position="239"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="77"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="OBZ85449.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="469" mass="53385" checksum="4033EE42C8359180" modified="2016-11-30" version="1">MSRHEDDSASDYSVVVSVHSDEEEDLEDYKKGGYHPVVIGERFDNNRYIVVRKLGWGHFSTVWLALDTQTDCHVALKIVKSADRYTESALEEIKLLEGVKNTNPKSKGYQYIAQMLSHFWHHGPNGKHACMTFEVLGESLLSLMKRYDYNGIPQHIVKRIAKQMLEGLDYLHRECGIVHTDLKPENVLVCIPHVEEYLKQDTAQVLQEIQQIDQPTTSPQPTVNQPPQPASDTQPLSKSQKKRLKKKKRKMLAGTSNQEASLDISHRLNSLTLANGKPKVISSSTLDITSIMSDTKGKEAFDDIVVKIADLGNACWMDGEYTHVIQTRQYRSPEVIVGAKWTDKADMWSMACMIFELLTGEFLFEPRAGSGYDKDDDHLAQMLELLRTAPKALITGGEFSREFFDRTGKLRRIKNLRYRRLQDLLHDTFAMSRKEADAISAFLLPMLDMDMSKRAPPNQMLLSPWLSDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NAD5</accession>
    <name>A0A1C7NAD5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Transcriptional repressor rco-1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">rco-1_1</name>
        <name evidence="12" type="ORF">A0J61_05857</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the WD repeat TUP1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000329">
        <property type="protein sequence ID" value="OBZ86092.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NAD5"/>
    <dbReference type="FunCoup" id="A0A1C7NAD5">
        <property type="interactions" value="145"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NAD5"/>
    <dbReference type="InParanoid" id="A0A1C7NAD5"/>
    <dbReference type="OrthoDB" id="17410at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.10:FF:000503">
        <property type="entry name" value="Glucose repression regulatory protein TUP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.340">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013890">
        <property type="entry name" value="Tscrpt_rep_Tup1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19848:SF8">
        <property type="entry name" value="F-BOX AND WD REPEAT DOMAIN CONTAINING 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19848">
        <property type="entry name" value="WD40 REPEAT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08581">
        <property type="entry name" value="Tup_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="6"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0678">Repressor</keyword>
    <keyword evidence="6" id="KW-0804">Transcription</keyword>
    <keyword evidence="5" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="3 9" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="Transcriptional repressor Tup1 N-terminal" evidence="11">
        <location>
            <begin position="16"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="9">
        <location>
            <begin position="309"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="9">
        <location>
            <begin position="344"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="9">
        <location>
            <begin position="391"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="9">
        <location>
            <begin position="433"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="9">
        <location>
            <begin position="486"/>
            <end position="527"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="9">
        <location>
            <begin position="528"/>
            <end position="560"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="87"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="87"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="10">
        <location>
            <begin position="117"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="10">
        <location>
            <begin position="140"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="10">
        <location>
            <begin position="180"/>
            <end position="189"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00060760"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF08581"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="OBZ86092.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="568" mass="61870" checksum="2884FDA287AE3FB5" modified="2016-11-30" version="1">MSVYNHRPMGPPTPSRLIELLDAVKNEYDQLAQEVIVCKNQRDEYEHKMNNQIQEMNLFQQNLIDLERTQQVIKKQYEEEIARLRQQLDQQTQHAQQHGSAPLPPVTGSGYGGPAGYQPPPPQVPPPSLMDSKAPAHHPNYPPTGPPPPAGPPHPTSAVSGPPHPSSGTPYINGGSPLPSNAPPPPPPSSQITTARPGVSSVKSGAGPHNTGASEALGDINPESVPANMKVEGQDWFALFNPKATRYLKVDLAHTFDHGSVVCCVKFSADGRYLAAGCNQATYIYDTLTSARVAVLQDENAGRDGDLYIRSVSFSPDGKFLATGAEDKQIRIWEISKKRIRGILSGHEQDIYSLEFSRDGRILVSGSGDRTARIWDWQSIRCLHELRITDADQQDLGVTSVAISPDSRLVAAGSLDKVVRVWDAVNGQLLERLEGHKDSVYSVAFMPDGKTLVSGSLDKTLRMWQLGAGERAGYGNDRKSACIQVFTGHKDFVLSVATTPDGNWIVSGSKDRGVQFWDPRTGQTQFMLQGHKNSVISVATSPGHKPMFATGSGDNRARIWTYEPLGAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NAJ5</accession>
    <name>A0A1C7NAJ5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_05822</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000326">
        <property type="protein sequence ID" value="OBZ86127.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="InParanoid" id="A0A1C7NAJ5"/>
    <dbReference type="OrthoDB" id="2206081at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="54"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="85"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="118"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="169"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="212"/>
            <end position="233"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ86127.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="345" mass="40190" checksum="A4881306E44688D3" modified="2016-11-30" version="1">MRISKKSRDIMIQLSPFGERVIDRINMIGMWVAVTISVRNFIICLRQYRRTHGLIHLMNIGQVTILIIHRFVYGLVPLFEITTCAFWPFLVSLWHLNFVLMYCIMFKRLLILEADKRTFWIKIAGALLITLRFADWPYELAFHTLQLELMQQHVQSGSNCLAQWGSGVILLNFIADALANLFLSGMFVRRLYMHIRSSRTLMSHRXQVIEYIARKSLVCLILTFAVNLTMNLLKITRFIGNRSDAFTVYFEIIESTLLVEALRVDHTQLPEQSFCEHCGMVMTSYGKEQHRSPVNKTSKKQQVSDIDHVHIPTRISYHNSSAYTDIQLMSVSEQHESRNYSSRNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NAJ6</accession>
    <name>A0A1C7NAJ6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Siderophore iron transporter mirC</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">mirC_0</name>
        <name evidence="8" type="ORF">A0J61_05878</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000331">
        <property type="protein sequence ID" value="OBZ86071.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NAJ6"/>
    <dbReference type="STRING" id="101091.A0A1C7NAJ6"/>
    <dbReference type="InParanoid" id="A0A1C7NAJ6"/>
    <dbReference type="OrthoDB" id="2241241at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501:SF87">
        <property type="entry name" value="SIDEROPHORE IRON TRANSPORTER 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="26"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="62"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="92"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="121"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="151"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="182"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="243"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="270"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="314"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="381"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="407"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="440"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="511"/>
            <end position="532"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="28"/>
            <end position="535"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="558"/>
            <end position="579"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OBZ86071.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="579" mass="63771" checksum="BDD14E8DDB18C4E7" modified="2016-11-30" version="1">MYSESNPKGVQIAAASTAIATKLDKIMVFICLALVSWIISWEKNIVNTITPTVTSEFQSNNLSGVLTIVLGVLQAALQPMYSKFADMIGRPITYTVCLVIFVVSFVAMACSHNYNALIGGQVVYAFGYSGIYVLGPILIGDSTSLANRTLVLAFYNFPLIINLFAGSAAAQKMLETVGWRWAFGHISIIAFVASIPIVVTLWVIQRRVFKSGLITQNEQTSEHNQTKGLAYFLRRSAWWMYEIDLLGSLLLIAGLLLLLLPLVLARTWGGWGTVSVIACLATSGATWIIFTIWEWKFTTKPIIPMKRWESFNPLYGTIIMCLVWTINGMMDLQYFLTYLKVTRRVKSNIAVYLERGFNATNVVMAVPIGFAVRGTRRWRPFVWAGACFVVLGTGLMIPARNSHSPDVFIVMSQILLGAGCASMNYPTLVGIQGSVPHRDIAVVIAMFELGIAIAQSIGSAIAGAIWNSVLPGLFHQYVPGQYEYKKITSSIPYALALPQDQYEGVVKAYDAAMHILSIVAVCIGALVFLIALQLKGYSLDRNQHEIGEADMIDETAIEHKEMSKEGREPSLTRTDSPKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NAN5</accession>
    <name>A0A1C7NAN5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Acyl-coenzyme A oxidase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="primary">ACX1.2_1</name>
        <name evidence="18" type="ORF">A0J61_06265</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18 19">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a 2,3-saturated acyl-CoA + O2 = a (2E)-enoyl-CoA + H2O2</text>
            <dbReference type="Rhea" id="RHEA:38959"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16240"/>
            <dbReference type="ChEBI" id="CHEBI:58856"/>
            <dbReference type="ChEBI" id="CHEBI:65111"/>
            <dbReference type="EC" id="1.3.3.6"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="4">Lipid metabolism; peroxisomal fatty acid beta-oxidation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Peroxisome</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5 12">Belongs to the acyl-CoA oxidase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000370">
        <property type="protein sequence ID" value="OBZ85686.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NAN5"/>
    <dbReference type="STRING" id="101091.A0A1C7NAN5"/>
    <dbReference type="InParanoid" id="A0A1C7NAN5"/>
    <dbReference type="OrthoDB" id="538336at2759"/>
    <dbReference type="UniPathway" id="UPA00661"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005777">
        <property type="term" value="C:peroxisome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003997">
        <property type="term" value="F:acyl-CoA oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005504">
        <property type="term" value="F:fatty acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033540">
        <property type="term" value="P:fatty acid beta-oxidation using acyl-CoA oxidase"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055088">
        <property type="term" value="P:lipid homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.140.10:FF:000015">
        <property type="entry name" value="Acyl-coenzyme A oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.110.10:FF:000003">
        <property type="entry name" value="Acyl-coenzyme A oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.540.10">
        <property type="entry name" value="Acyl-CoA dehydrogenase/oxidase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.110.10">
        <property type="entry name" value="Butyryl-CoA Dehydrogenase, subunit A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.140.10">
        <property type="entry name" value="Butyryl-CoA Dehydrogenase, subunit A, domain 3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055060">
        <property type="entry name" value="ACOX_C_alpha1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029320">
        <property type="entry name" value="Acyl-CoA_ox_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046373">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012258">
        <property type="entry name" value="Acyl-CoA_oxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002655">
        <property type="entry name" value="Acyl-CoA_oxidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036250">
        <property type="entry name" value="AcylCo_DH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037069">
        <property type="entry name" value="AcylCoA_DH/ox_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009100">
        <property type="entry name" value="AcylCoA_DH/oxidase_NM_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10909">
        <property type="entry name" value="ELECTRON TRANSPORT OXIDOREDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10909:SF250">
        <property type="entry name" value="PEROXISOMAL ACYL-COENZYME A OXIDASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01756">
        <property type="entry name" value="ACOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22924">
        <property type="entry name" value="ACOX_C_alpha1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14749">
        <property type="entry name" value="Acyl-CoA_ox_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000168">
        <property type="entry name" value="Acyl-CoA_oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47203">
        <property type="entry name" value="Acyl-CoA dehydrogenase C-terminal domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56645">
        <property type="entry name" value="Acyl-CoA dehydrogenase NM domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 12 14" id="KW-0274">FAD</keyword>
    <keyword evidence="8" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="6 12" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="10" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-0576">Peroxisome</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Acyl-coenzyme A oxidase N-terminal" evidence="16">
        <location>
            <begin position="24"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA oxidase C-alpha1" evidence="17">
        <location>
            <begin position="282"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA oxidase C-terminal" evidence="15">
        <location>
            <begin position="486"/>
            <end position="653"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="13">
        <location>
            <position position="430"/>
        </location>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="144"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="183"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004275"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00006288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRNR" id="PIRNR000168"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR000168-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PIRSR" id="PIRSR000168-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF01756"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF14749"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF22924"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="OBZ85686.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="674" mass="75296" checksum="58E2E3F210F903DA" modified="2016-11-30" version="1">MNNKHLVQMTNDLQEARNRASFSPDAMHRFIHGSSDKVEKIDKMRSIIESEPVFSKSQIPFQGRPEQLHHSLLVCKRLIELAEEMNMSDEDFAILTKQAHMLTPLSLHYSAFMAVIKAQGTQEQVDKWYTASKRHAVLGCYAQTELSHGSNVMGLGTLATYDSKTQEFIIHTPDITAAKWWIGGLGVTSTHAVVQAQLIISGKSYGPHLFIVPIRSPIDLKPLKGIQVGDIGPKAYGGFSTMDNGYVIFDHVRIPRNNMLMKFAKVTPEGKYLPPVHDKLSYGSMVKLRVDIVDAAGWNLARAITVAVRYCTVRRQFNSENDNSGLETQVINYSSVQHRLMPLLATAYGVIFTGDTLFKRFDQLLAQLEVNDTTLLPEMHATACALKSWGTRRSTDGIEDARKCMGGHGFSYFSGLSDLFASNVPSNTYEGDNYVLSQQTARFLLKQLSLAASGKSVSSDTASYLYLLKEKDTFKFSNLKQEILEPKVQLKLFGIRTARLVANLARQLQRNVPWSELNMDCWAINLAHAEYLVMNEFVNRLTEAQSSEQQVLLPVIKSLSDMFGLSTILNTSLATFLSTSTINPSDLDELNSVYRKLVAEVSMNAVPLVDSFGFTDKTLDSALGRYDGRAYEALWEAAQRNPLNKGKELAKLQDAVLQIVHRGNNLEYIKTSKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NAV5</accession>
    <name>A0A1C7NAV5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_05707</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000316">
        <property type="protein sequence ID" value="OBZ86242.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="InParanoid" id="A0A1C7NAV5"/>
    <dbReference type="OrthoDB" id="2439595at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="39"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ86242.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="363" mass="41959" checksum="5818756CB19EBEB6" modified="2016-11-30" version="1">MNSLASTPSITSLTSRPAAVNDTREKMVERRNKLFQDSQERLLDQLKSLHVQLDKQKNEQAQIEQQLASSKESNQKLRKEVHQLQNQLYETTKPIRVTDDDYSTIIAQLNKFIGKVNNFPPNAKSHFNQANRSKEEVTQFFCQLWQEDQQEIEILFQQENQPTDKLDYSLISNLVERYLIDRTLKHLLMADKIHLDSSLNTCYAKMDSLYRKTGHQDWANDLRLKTAKATAELIHLNDAETLEATQATKEAIVQDILSTLLFLFDTSQEDIKKRIEKIVDMAAELSLPIHGQEDVIEIYDLKKGDPIKQAQVKHTYRQLNRDTVLLSISPVFLAKSTVESEDDINPDTYIXHHTLVYPGRAIW</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NB24</accession>
    <name>A0A1C7NB24_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="26">Pyrimidine-specific carbamoyl phosphate synthase-aspartate carbamoyl transferase</fullName>
            <ecNumber evidence="6">2.1.3.2</ecNumber>
            <ecNumber evidence="5">3.5.1.2</ecNumber>
            <ecNumber evidence="20">6.3.4.16</ecNumber>
            <ecNumber evidence="4">6.3.5.5</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="31" type="primary">pyrABCN_1</name>
        <name evidence="31" type="ORF">A0J61_07405</name>
    </gene>
    <organism evidence="31 32">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="31 32" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="31 32">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="25">Multifunctional protein that encodes the first 2 enzymatic activities of the de novo pyrimidine pathway: carbamoylphosphate synthetase (CPSase; EC 6.3.5.5) and aspartate transcarbamylase (ATCase; EC 2.1.3.2). The CPSase-function is accomplished in 2 steps, by a glutamine-dependent amidotransferase activity (GATase) that binds and cleaves glutamine to produce ammonia, followed by an ammonium-dependent carbamoyl phosphate synthetase, which reacts with the ammonia, hydrogencarbonate and ATP to form carbamoyl phosphate. The endogenously produced carbamoyl phosphate is sequestered and channeled to the ATCase active site. ATCase then catalyzes the formation of carbamoyl-L-aspartate from L-aspartate and carbamoyl phosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="24">
            <text>L-glutamine + H2O = L-glutamate + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:15889"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="EC" id="3.5.1.2"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="23">
            <text>carbamoyl phosphate + L-aspartate = N-carbamoyl-L-aspartate + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:20013"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29991"/>
            <dbReference type="ChEBI" id="CHEBI:32814"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58228"/>
            <dbReference type="EC" id="2.1.3.2"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="22">
            <text>hydrogencarbonate + L-glutamine + 2 ATP + H2O = carbamoyl phosphate + L-glutamate + 2 ADP + phosphate + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:18633"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17544"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58228"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.5.5"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="21">
            <text>hydrogencarbonate + NH4(+) + 2 ATP = carbamoyl phosphate + 2 ADP + phosphate + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:18029"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17544"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58228"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.4.16"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Pyrimidine metabolism; UMP biosynthesis via de novo pathway; (S)-dihydroorotate from bicarbonate: step 1/3.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3">Pyrimidine metabolism; UMP biosynthesis via de novo pathway; (S)-dihydroorotate from bicarbonate: step 2/3.</text>
    </comment>
    <comment type="similarity">
        <text evidence="19">In the 2nd section; belongs to the CarB family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="16">In the 3rd section; belongs to the metallo-dependent hydrolases superfamily. DHOase family. CAD subfamily.</text>
    </comment>
    <comment type="similarity">
        <text evidence="17">In the C-terminal section; belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="18">In the N-terminal section; belongs to the CarA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="31">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.3.2" evidence="6"/>
    <dbReference type="EC" id="3.5.1.2" evidence="5"/>
    <dbReference type="EC" id="6.3.4.16" evidence="20"/>
    <dbReference type="EC" id="6.3.5.5" evidence="4"/>
    <dbReference type="EMBL" id="LUGH01000498">
        <property type="protein sequence ID" value="OBZ84544.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="FunCoup" id="A0A1C7NB24">
        <property type="interactions" value="612"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NB24"/>
    <dbReference type="InParanoid" id="A0A1C7NB24"/>
    <dbReference type="OrthoDB" id="1924069at2759"/>
    <dbReference type="UniPathway" id="UPA00070">
        <property type="reaction ID" value="UER00115"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005951">
        <property type="term" value="C:carbamoyl-phosphate synthase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016597">
        <property type="term" value="F:amino acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004070">
        <property type="term" value="F:aspartate carbamoyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004087">
        <property type="term" value="F:carbamoyl-phosphate synthase (ammonia) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004088">
        <property type="term" value="F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004359">
        <property type="term" value="F:glutaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006207">
        <property type="term" value="P:'de novo' pyrimidine nucleobase biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="entry name" value="ATCASE"/>
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    <keyword evidence="10" id="KW-0677">Repeat</keyword>
    <keyword evidence="9" id="KW-0808">Transferase</keyword>
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        <location>
            <begin position="25"/>
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    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="28">
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        <source>
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        <source>
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        <source>
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        <source>
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        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
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    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
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    </evidence>
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        <source>
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        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
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    </evidence>
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        <source>
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    </evidence>
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        <source>
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    <evidence type="ECO:0000256" key="13">
        <source>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022975"/>
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    <evidence type="ECO:0000256" key="15">
        <source>
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        <source>
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    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00043979"/>
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    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00043984"/>
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    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00043998"/>
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    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="ARBA" id="ARBA00044063"/>
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    </evidence>
    <evidence type="ECO:0000256" key="21">
        <source>
            <dbReference type="ARBA" id="ARBA00047359"/>
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    </evidence>
    <evidence type="ECO:0000256" key="22">
        <source>
            <dbReference type="ARBA" id="ARBA00048816"/>
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    </evidence>
    <evidence type="ECO:0000256" key="23">
        <source>
            <dbReference type="ARBA" id="ARBA00048859"/>
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    </evidence>
    <evidence type="ECO:0000256" key="24">
        <source>
            <dbReference type="ARBA" id="ARBA00049534"/>
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    </evidence>
    <evidence type="ECO:0000256" key="25">
        <source>
            <dbReference type="ARBA" id="ARBA00058513"/>
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    </evidence>
    <evidence type="ECO:0000256" key="26">
        <source>
            <dbReference type="ARBA" id="ARBA00081752"/>
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    </evidence>
    <evidence type="ECO:0000256" key="27">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00409"/>
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    </evidence>
    <evidence type="ECO:0000256" key="28">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
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    </evidence>
    <evidence type="ECO:0000259" key="29">
        <source>
            <dbReference type="PROSITE" id="PS50975"/>
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    </evidence>
    <evidence type="ECO:0000259" key="30">
        <source>
            <dbReference type="PROSITE" id="PS51855"/>
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    </evidence>
    <evidence type="ECO:0000313" key="31">
        <source>
            <dbReference type="EMBL" id="OBZ84544.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="32">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="2278" mass="250814" checksum="0E475111D17FCCA1" modified="2016-11-30" version="1">MSNFPIPSVAAAGTAPAINTGANIPAPAAHATPLPTQSPRSTAGPHRPVTAFEDKDITTAALVLEDGTSYQGISFGAEARSISGECVFQTGMVGYPESLTDPSYRGQILVLTFPLVGNYGAPSRDDMDELLKDIPKYYESNEIHVAGLIVGNYATDYSHYLASSSLSAWLKENNVPALYGIDTRAMTKKIRIQGALLAKILFPQSNMGHTVDAAASALGLSSHKSSSDSWLSNYQDVEWVDPNKRNLVAEVSLKEPKVYSPEPSKALKTPSGRTIRIIAVDIGMKYNQIRCFVFRGVELKIVPWDYDFNNEPLDSFDGLFLSNGPGDPTTIEATIQNTRKFLQDLKKPVFGICLGHQIMSLAAGAKTMKMKYGNRGQNIPCTNLLSGRCYITSQNHGYAVDAASLPSDYQELFVNANDGSNEGVIHKTKPIFSVQFHPESTPGPRDSEFLFDVFLENVKECLETKSLVPLRIPGGTLVENRNKNPRVHVNKVLVLGSGGLSIGQAGEFDYSGSQAIKALKEEGIYTVLINPNIATIQTSKGLADKVYFLPVTPDYVRKVIQFEKPDGIYVTFGGQTALSVGIALKDEFESLGVKVLGTPIDTIITTEDRDLFAQALYEINEKCAQSSSAVTVEEALAAAKEIGYPVICRAAYALGGLGSGFADNEKELSALCNKAFATSPQVLIEKSMKGWKEIEYEVVRDCQDNCITVCNMENFDPLGIHTGDSIVVAPSQTLSDADYHMLRTTAVNVIRHLGVVGECNIQYALDPFSKEYCIIEVNARLSRSSALASKATGYPLAFVAAKLGLGIPLNEIKNSVTKVTCACFEPSLDYVVVKIPRWDLKKFNRVSTALSSSMKSVGEVMAIGRTFEETIQKAIRAIDYNFTGFSENTFVADESLDFELSNPSDQRLFAIANAMNKGYTVDKIWEMTNIDKWFLNKLMHIVQLGKRLDGFNKTNVSGNLIRSAKQLGFSDRQIANHLNSNELAVRKLRQEYNVTPYVKQIDTVAAEFPAFTNYLYMTYNAVEHDIEFNDKGVMVLGSGVYRIGSSVEFDWCAVRAIRTIRQQGIKTVMVNYNPETVSTDYDEADRLYFENINLERVLDIYEIEKSTGVLMSMGGQTPNNIALPLYRQNVKVLGTSPEMIDNAENRYKFSRMCDSIGVDQPHWKELTNYEDAETFCENVGFPVLVRPSYVLSGAAMNVVFSKDDLASYLKEAAAVSREHPVVITKYIEEAKEVDMDAVALDGKLIMHVISEHVENAGVHSGDATLVLPPQDLDPETIRKIEEATAKIGRALNITGPFNIQFIAKNNEIKVIECNVRAARSSPFVSKVMGVDLIEMATLAMLGLPVVPYPKASIPKDYVGVKVPQFSFSRLSGADPVLGVEMASTGEVACFGKDKFQAYLKALLATGFRVPKKNILFSIGSYKEKQELLPSVRKLHELGYNIFATTGTADFISEHGIPVKHLDTLDADTDDKLKAEYSLQQHLSNNLIDLYINLPSRNRFRRPASYMSKGYRSRRMAVDYSVPLLTNVKCAKLFIEAIASNKDNRILDIDCKTSHTQAHLPGLFNINAYLESSDEFEAVAKASLSAGFTTISAFTKNVTSDTALDELSHAARKSAHTDYLLNITATAENAKQVGKYASDAAAVYINTDLLGSGKVSVFDSVFSSWPTSQLIITDARGTDLASILLLASLHNRIIHVSNLMNKADLALIKMSKKKGLSVTCDVSVYSLFFHSEDFNNTKFLPSKDEHDALWKNLDVIDCFSIGYTPRKIAAEVGQNSDATAGIHESLALLLGAVHHGRLTLNDVIKRLCDNPRAIFGIPPQSDTSVEIVIDRKYTWPVSKESWSPLAGITVYGSVERVILDETNMFMDGVLVNTSKHGRDISVQAQNVKSGAAAKQSERQKEEEVSEGQKERHKQQVEKSLAVLESGAVKEDRAPRASDPIRLAGSTGQQLISLQAPQYEVSASLARVVSRSPFYRKHILRAAQFDRDDLHLLFGVAHEMRNLVELYGSINLLQGRVISTMFFEPSTRTSSSFEAAMYRLGGQVVPVSATTSSVQKGESLADTMRTLGCYSDLIVIRHPQPGSAQIAAKYSKVPIINAGDGIGEHPTQAFLDTFTIREELGTVNGLSITLVGDLKNGRTVHSLVKILTYYQVTINYVSPDSLPMPKEIVDEAKAAGIKQNFYSSLDEVIGATDVLYMTRVQKERFGSEEEYRRVKDSFILNNDVLSKAKAHMIVLHPLPRVNEIEPEVDFDQRAAYFRQMRYGLYVRMALLALVLGTLRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NB86</accession>
    <name>A0A1C7NB86_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">RlpA-like protein double-psi beta-barrel domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_07351</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000490">
        <property type="protein sequence ID" value="OBZ84604.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NB86"/>
    <dbReference type="STRING" id="101091.A0A1C7NB86"/>
    <dbReference type="InParanoid" id="A0A1C7NB86"/>
    <dbReference type="OrthoDB" id="623670at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd22191">
        <property type="entry name" value="DPBB_RlpA_EXP_N-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.40.10">
        <property type="entry name" value="RlpA-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051477">
        <property type="entry name" value="Expansin_CellWall"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009009">
        <property type="entry name" value="RlpA-like_DPBB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036908">
        <property type="entry name" value="RlpA-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31836">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31836:SF28">
        <property type="entry name" value="SRCR DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03330">
        <property type="entry name" value="DPBB_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50685">
        <property type="entry name" value="Barwin-like endoglucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="domain" description="RlpA-like protein double-psi beta-barrel" evidence="2">
        <location>
            <begin position="63"/>
            <end position="127"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03330"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ84604.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="138" mass="14993" checksum="0389F09CEF3EB7E8" modified="2016-11-30" version="1">MFNVCQARETDGEHVKLGLGRVVDLIENIFKGTGTFFHPASEGGAIGSCGPKASDHSRICAMNIKQYGKASRKSPWCFVQLRVKYKGKETYCTVTDCCPGCNEGSLDMTPEVFNDLAHPNVGVIPIEWCVVGYRGSAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-06-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NBG4</accession>
    <name>A0A1C7NBG4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_05517</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000299">
        <property type="protein sequence ID" value="OBZ86437.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NBG4"/>
    <dbReference type="InParanoid" id="A0A1C7NBG4"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ86437.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="97" mass="11123" checksum="0A932B1EB4C4F35E" modified="2016-11-30" version="1">MPELRYAPDEKKALFNYKWKEGYTNSLVQNECELTLKKTIKPKPDPSYATREARSYYIIADVTRMAIIFSMEHIKEGKSPDTTVQVIPSSSQHAAIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NBQ2</accession>
    <name>A0A1C7NBQ2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Cell division control protein 25</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">CDC25_0</name>
        <name evidence="11" type="ORF">A0J61_07178</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000471">
        <property type="protein sequence ID" value="OBZ84774.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="FunCoup" id="A0A1C7NBQ2">
        <property type="interactions" value="61"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NBQ2"/>
    <dbReference type="InParanoid" id="A0A1C7NBQ2"/>
    <dbReference type="OrthoDB" id="546434at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005085">
        <property type="term" value="F:guanyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007265">
        <property type="term" value="P:Ras protein signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00155">
        <property type="entry name" value="RasGEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd06224">
        <property type="entry name" value="REM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00201">
        <property type="entry name" value="WW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.30.40:FF:000072">
        <property type="entry name" value="Unconventional Myosin IB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.70.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.840.10">
        <property type="entry name" value="Ras guanine-nucleotide exchange factors catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.40">
        <property type="entry name" value="SH3 Domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.870.10">
        <property type="entry name" value="Son of sevenless (SoS) protein Chain: S domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.3960">
        <property type="entry name" value="Velvet domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056685">
        <property type="entry name" value="DUF7783"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008937">
        <property type="entry name" value="Ras-like_GEF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000651">
        <property type="entry name" value="Ras-like_Gua-exchang_fac_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019804">
        <property type="entry name" value="Ras_G-nucl-exch_fac_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023578">
        <property type="entry name" value="Ras_GEF_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001895">
        <property type="entry name" value="RASGEF_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036964">
        <property type="entry name" value="RASGEF_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036028">
        <property type="entry name" value="SH3-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001452">
        <property type="entry name" value="SH3_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037525">
        <property type="entry name" value="Velvet_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038491">
        <property type="entry name" value="Velvet_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001202">
        <property type="entry name" value="WW_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036020">
        <property type="entry name" value="WW_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23113:SF368">
        <property type="entry name" value="CELL DIVISION CONTROL PROTEIN 25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23113">
        <property type="entry name" value="GUANINE NUCLEOTIDE EXCHANGE FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25006">
        <property type="entry name" value="DUF7783"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00617">
        <property type="entry name" value="RasGEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00618">
        <property type="entry name" value="RasGEF_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00018">
        <property type="entry name" value="SH3_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11754">
        <property type="entry name" value="Velvet"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00397">
        <property type="entry name" value="WW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00147">
        <property type="entry name" value="RasGEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00229">
        <property type="entry name" value="RasGEFN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00326">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00456">
        <property type="entry name" value="WW"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48366">
        <property type="entry name" value="Ras GEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50044">
        <property type="entry name" value="SH3-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51045">
        <property type="entry name" value="WW domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00720">
        <property type="entry name" value="RASGEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50009">
        <property type="entry name" value="RASGEF_CAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50212">
        <property type="entry name" value="RASGEF_NTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50002">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51821">
        <property type="entry name" value="VELVET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50020">
        <property type="entry name" value="WW_DOMAIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="11" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="11" id="KW-0132">Cell division</keyword>
    <keyword evidence="2 3" id="KW-0344">Guanine-nucleotide releasing factor</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0728">SH3 domain</keyword>
    <feature type="domain" description="SH3" evidence="6">
        <location>
            <begin position="5"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="domain" description="WW" evidence="8">
        <location>
            <begin position="227"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="domain" description="N-terminal Ras-GEF" evidence="9">
        <location>
            <begin position="728"/>
            <end position="858"/>
        </location>
    </feature>
    <feature type="domain" description="Ras-GEF" evidence="7">
        <location>
            <begin position="896"/>
            <end position="1132"/>
        </location>
    </feature>
    <feature type="domain" description="Velvet" evidence="10">
        <location>
            <begin position="1128"/>
            <end position="1305"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="635"/>
            <end position="673"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1306"/>
            <end position="1354"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1412"/>
            <end position="1504"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="640"/>
            <end position="649"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="1306"/>
            <end position="1315"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="1316"/>
            <end position="1335"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="1420"/>
            <end position="1443"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="1459"/>
            <end position="1471"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="1484"/>
            <end position="1493"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022658"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00168"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50009"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51821"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="OBZ84774.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="1504" mass="171373" checksum="5988BA1576C3CE90" modified="2016-11-30" version="1">MNKPDVICRVRALYSYRSTESSSLSFHADSIIEVLCQLDSGWWDGWCDGRRGWFPSNYVEVIPESDAPWSPLDPPKRTQRTLIQTEAKKQLRLSLHAADTNLANFEVGANCAPSLEDSPWVLQITEDGSEQYYYNKYTHEMRHSPPAELMMRNESHLSFNEGTFFQQQQEQQQYHFSPHRSAPPVRPVRAPNRIISDELTPSNRHTNLPIMLEEDPEDDFQDKGDIDKLPPNWVRKVTSKGQFFYYNIKTEESTFELENIDPDTGRLILNDLSMPGNGSLPTLDTSSSHSGQSSSPLIEPILETQKEPLTWHSLDDMISQAVESLRHTIQQNQLDYITQDATTIVHRVRLLLYVTHCIEKESSMYLRSHKSLRTMHRALMAALAKMVLSTKVASSAWPTADQLHKLDLDTTEVLISVRHFISTAQDLQVVIRKSIPTFKSDANDIWRNNPLVVQNPLGETIGHQNMMDHCLSLADHVRNAIDSYQGGFQCALQPFERNHHLQGTLDKLRLNAPLHVAQFRNLSNATSEFLNGLEEICQAQPHHVRTLALVKAKQPIYQAMGGLFVVAQTVASTDLDAYQIKTSKERLEACIQTIRDGLDNVIQTVRDISPDELVHESHPIRNNSVDSIPTVMTPQHDAQEESVEQEDEASLLKTESDPPLADPSSDKSQTAHQQKDKLAKLAGFFGEDALGPNRLNRLPSMTSFSSQGAEPDWFLKSDYHPDEIAFNMEGNVKGGTLHSLVQYMTQHDQLDSKFNSTFLLTYRSFCTTEELFEELFQRYQLPIPEGLSPEEFERWKEKKLKLVRLRVFNIIKSWLETYFNEEEDRPILISIDRFTETVIADTMKFGAEQLTKLIKKRMMAEESGQIRKMKLNFRTGDMPVPILPKNMKHIKLLEVDPLELARQLTVMDFKLYNRIKPVECLDKNWGKADLGDYIAVNIRASIEHSNQVTAWVTDSILSKDNIKKRATVMKHWILVAERCRSLQNFNTCMAILSAFDNGSIGRLKRTWELMSTRSMATLQNIRKLMGANRNFSEYRELIKKINPPCIPFLGIYLQDLTFIDDGNSNLLKKSNNLINFSKRMKTAEVIRDLQQYQSTHYMLSAVPDLQEFIKTHLHSSREDEELYSLSLKLEPSDYQLTLRQQPKQSRMCGIGEKADRRPIDPPPIVQLKVIDPSLPVSERNAYLQNPYYFMYASLMAADLDEELHLLRDGKTRSTTGSVVSSLYHLKDIDNTDAGFFVFPDLSVRMEGSYRLKLSLFEIIGKEVYHCRSIISNKFFVYSAKKFPGMEESTFLSRSFADQGLKIRIRKELRQRRNKGKTAEDDTAHKKQKTMRDREQSLPPTSPHYNRDHSLPAPTRFISYSSRQPIQNNNNSNSNTIQQTDQATVAAQAAVVQAAAAAAASVSWGGPMLETKYRPSSYHPSTPPPQPPPLPTSTPITQPPPPPSLHHYHHPHSHYYATPPSLPPPPPPPPPTSDIITPHHHHVHTNTSSSSSISRPDLIGKYLPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NBW9</accession>
    <name>A0A1C7NBW9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Transcription factor</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">prr1_0</name>
        <name evidence="12" type="ORF">A0J61_05697</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 8">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000315">
        <property type="protein sequence ID" value="OBZ86259.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NBW9"/>
    <dbReference type="FunCoup" id="A0A1C7NBW9">
        <property type="interactions" value="267"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NBW9"/>
    <dbReference type="InParanoid" id="A0A1C7NBW9"/>
    <dbReference type="OrthoDB" id="60033at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000156">
        <property type="term" value="F:phosphorelay response regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd17546">
        <property type="entry name" value="REC_hyHK_CKI1_RcsC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.10:FF:000027">
        <property type="entry name" value="Heat shock transcription factor 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000232">
        <property type="entry name" value="HSF_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014402">
        <property type="entry name" value="Sig_transdc_resp-reg_Skn7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45339">
        <property type="entry name" value="HYBRID SIGNAL TRANSDUCTION HISTIDINE KINASE J"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45339:SF1">
        <property type="entry name" value="HYBRID SIGNAL TRANSDUCTION HISTIDINE KINASE J"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00447">
        <property type="entry name" value="HSF_DNA-bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002595">
        <property type="entry name" value="RR_SKN7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00056">
        <property type="entry name" value="HSFDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00415">
        <property type="entry name" value="HSF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="CheY-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF58104">
        <property type="entry name" value="Methyl-accepting chemotaxis protein (MCP) signaling domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00434">
        <property type="entry name" value="HSF_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 8" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7 8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="2 9" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 8" id="KW-0804">Transcription</keyword>
    <keyword evidence="4 8" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="3" id="KW-0902">Two-component regulatory system</keyword>
    <feature type="domain" description="Response regulatory" evidence="11">
        <location>
            <begin position="333"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="122"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="276"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="516"/>
            <end position="547"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="127"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="276"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="534"/>
            <end position="547"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="9">
        <location>
            <position position="382"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRNR" id="PIRNR002595"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="OBZ86259.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="596" mass="67606" checksum="616A7FA3C6EF2DAF" modified="2016-11-30" version="1">MLSSSPSINDSHHSNLPNSNNIPEFVKKLFSMLEENTYPQVFSWGIDGNTFVVKDPNEFARHILPKHFKHSNFASFVRQLNKYDFHKLRMPEDGQRIYGDRAWEFQHPNFKYNRRELLEEIKRKPTGKSSQTTGQTNASTPSTTVAGRLNSVSAGVTEELKALTNTLQSEIFQLKETQKKMTDKIKTFDKKYNVVLDSIQGFKKSMEEQDTVMREIVAFVKQQNTNTEEMDKVVQAYNHAANTSEIQLERLAETMASGSATATPIVMNQAITVDTQMDQPSPQPQQLQQTNNNGNTADSSNNNSNSIVPVINTSAPISRKRKRIQLGWTVPPRVLLVDDDSIFRRLSTRLLQIAGCTIDVAVDGMEAVKKLGSGKYDLVLMDIMMPKLDGMSATRNIRQYDTWTPIISMTSNTTDQAIQQYFMSGMTDILPKPFNQGSLGSLLERYCAHLVVQRQHQQQLHLLQQNFSLNNTLLDSNIMRPQLTLIEDEDDEKKNKINCVEENNANLTFIPSQTFISDNNNNNNNNNESSVTILQPSSQSSVSLPQQSQEQALYSQLNIIPQLAQPNALQTQQQEWYLYANQKRPRIDDMSSNNNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NC41</accession>
    <name>A0A1C7NC41_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_05641</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000310">
        <property type="protein sequence ID" value="OBZ86309.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NC41"/>
    <dbReference type="InParanoid" id="A0A1C7NC41"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008889605" evidence="2">
        <location>
            <begin position="20"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="144"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="147"/>
            <end position="166"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ86309.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="166" mass="18343" checksum="FD51627CD6C38EB7" modified="2016-11-30" version="1">MRFITVSLALVVPFLLASSAASIGRRDTQMISMVSQDGSQAQNIVAVHDIDRTRELDTQNNSNLVASNSGNVPASGQTQVGTMVSSEQAERVYMVMPSDEDDLDEMNEVLLLNGNVNPPPRQNENVVMTRERLENERDELLRKRDYDSDELELDAAELGGDSDDTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NCK2</accession>
    <name>A0A1C7NCK2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Thermolabile hemolysin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">A0J61_06864</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000435">
        <property type="protein sequence ID" value="OBZ85084.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NCK2"/>
    <dbReference type="InParanoid" id="A0A1C7NCK2"/>
    <dbReference type="OrthoDB" id="1600564at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016788">
        <property type="term" value="F:hydrolase activity, acting on ester bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01846">
        <property type="entry name" value="fatty_acyltransferase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1110">
        <property type="entry name" value="SGNH hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001087">
        <property type="entry name" value="GDSL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051058">
        <property type="entry name" value="GDSL_Est/Lipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036514">
        <property type="entry name" value="SGNH_hydro_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45648">
        <property type="entry name" value="GDSL LIPASE/ACYLHYDROLASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_4G14700)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45648:SF22">
        <property type="entry name" value="GDSL LIPASE_ACYLHYDROLASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_4G14700)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00657">
        <property type="entry name" value="Lipase_GDSL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52266">
        <property type="entry name" value="SGNH hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008889617" evidence="3">
        <location>
            <begin position="21"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="359"/>
            <end position="377"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OBZ85084.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="413" mass="46495" checksum="67FC2CBA6BF28F66" modified="2016-11-30" version="1">MKSLLLLSSCLTVLTSTALAGLFSLQEEAEETVNQIVVFGDSYSDVGNKQRLSNGPLWSEHLAAGWNASHYNFAFSGAVCNNTMYAKQPLSEHYIPSIVDQVEMYYRQNYSFHQETAVSFWVGVSDVYKILETHEDPDIIQQEFKKVVDCIGTNLRHVRQAFSHTKFIVFNVPPMEYMPLYAHTEKAEKKKEAVIQLNEMLRKDIEKMNKHLQAIELDLVDVHKLIQDIVDKPGLFGIQNPQDAYWDHCQGQCADPIDSYVWWDKTHLTGGIHRLIANSILMSGSLAKETYLDDQLNVQQLLNQPHSIYRSPIFKAHQATGLMDRLIAEMNQKQHSTNQGSGSDLSQDEISSSSSHSQLAYLAIAGVAVVGLAAFIVKKKNKTGQLAALSGLIHKNNQDRGRFMPLRNLDSEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NDD1</accession>
    <name>A0A1C7NDD1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">RING-type E3 ubiquitin transferase</fullName>
            <ecNumber evidence="4">2.3.2.27</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="primary">RFWD3_0</name>
        <name evidence="18" type="ORF">A0J61_04819</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18 19">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.</text>
            <dbReference type="EC" id="2.3.2.27"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="13">Nucleus</location>
            <location evidence="13">Nuclear body</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.27" evidence="4"/>
    <dbReference type="EMBL" id="LUGH01000244">
        <property type="protein sequence ID" value="OBZ87122.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NDD1"/>
    <dbReference type="STRING" id="101091.A0A1C7NDD1"/>
    <dbReference type="InParanoid" id="A0A1C7NDD1"/>
    <dbReference type="OrthoDB" id="8062037at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016604">
        <property type="term" value="C:nuclear body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036297">
        <property type="term" value="P:interstrand cross-link repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016567">
        <property type="term" value="P:protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd16450">
        <property type="entry name" value="mRING-C3HGC3_RFWD3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037381">
        <property type="entry name" value="RFWD3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056527">
        <property type="entry name" value="WD40_RFWD3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16047:SF7">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE RFWD3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16047">
        <property type="entry name" value="RFWD3 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23419">
        <property type="entry name" value="WD40_RFWD3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13639">
        <property type="entry name" value="zf-RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="15" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9" id="KW-0227">DNA damage</keyword>
    <keyword evidence="11" id="KW-0234">DNA repair</keyword>
    <keyword evidence="14" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-0539">Nucleus</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0677">Repeat</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <keyword evidence="10" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="6" id="KW-0853">WD repeat</keyword>
    <keyword evidence="14" id="KW-0862">Zinc</keyword>
    <keyword evidence="14" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="17">
        <location>
            <begin position="35"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="197"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="15">
        <location>
            <begin position="110"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="16">
        <location>
            <begin position="203"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="16">
        <location>
            <begin position="227"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="16">
        <location>
            <begin position="264"/>
            <end position="273"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00034306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="OBZ87122.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="586" mass="66611" checksum="91F9F25D87E4C3ED" modified="2016-11-30" version="1">MSLTRVVDHVNDPTQKRCKLDLDSQSEEDDDSYMCTICSETWSSRGEHCLVSLKCGHLFGKKCIVRWIMDRSRKLGGSKAPCPMCMKAARQSDIRIVIPTRLAVKDITQSDLLKRELEALKIQIKESEKELELARLGLSLHKRELEKAKRQMSVLYPLSPEELALAEQISLESITEESVPEQPSPGQSVAEQLMDKEPATEEPMNEEPVNEEPATEESMNEETSSEQPSSDQPVTEQSSLQQPIETTSTSDQLDTEYSMRAQPIRTSTTKSQLPYSIVGSKRLSETRQVARVMTLNPEDQLAYISFKSNQHQHGIMTLDLATMTPHFTSLHENLVRDVRHSHFDKLILSTGLDKTAKLGSLQPGSQLSVSLSTAGWSCCFDALDANQFYIGLADSTIVAFDRRYPAEPYRSYQHPDISKTPLHSLFSTVQNHQSVLYGANLTQPFFYDTLTSHARFMTWLISDDKPYSFTRHAHHDAYLLSCRSKSLTRHYLFQPDQQQPMVVHSPFAQRGLTRTHAYGKENLADSIFCYAQEERGSLCLYQSGRELQQFQIHSAPLDIQPYYQDRFAFLTDNRFFLLQPTSFSSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NDG5</accession>
    <name>A0A1C7NDG5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Serine/threonine-protein kinase PRP4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">Prpf4b</name>
        <name evidence="9" type="ORF">A0J61_04816</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000244">
        <property type="protein sequence ID" value="OBZ87125.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NDG5"/>
    <dbReference type="STRING" id="101091.A0A1C7NDG5"/>
    <dbReference type="InParanoid" id="A0A1C7NDG5"/>
    <dbReference type="OrthoDB" id="9332038at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000123">
        <property type="entry name" value="serine/threonine-protein kinase PRP4 homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050494">
        <property type="entry name" value="Ser_Thr_dual-spec_kinase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24058">
        <property type="entry name" value="DUAL SPECIFICITY PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24058:SF103">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE PRP4 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 9" id="KW-0418">Kinase</keyword>
    <keyword evidence="3 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="8">
        <location>
            <begin position="329"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="24"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="58"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="173"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="210"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="358"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="384"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OBZ87125.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="384" mass="43789" checksum="19997EF067637E1B" modified="2016-11-30" version="1" fragment="single">MSNNKYEEYEAGEITSDNNYYRKRGVDDVYSNRHRYDSFEDDPFAEYERLSRSKKRRESPSRRHYPSDNRRRHSRESNNIKDKRENVYANRGDSNHHRRSRSPSSHRLTNVIAKQPAETKTISEPPVAVDFKDEEEQQKEEDRLIEERRKRRQAILSRYKPSSSTAAEETEATEATTTTGATAAAAATEDTQEPQPSPSSPITKADEPNSPDSPSQQISAADYDPSMDCATNTQAELLKVKDRQEHVTEGANSHTDMLASDYTEQLEQPSKAMEIDMFSDNLDMFAATDMTTTATTTDHAATNPSLIDNWDDPEGYYTTRIGEVLDERYQVLANLGRGVFSSVVKARDQQTQEEVAIKLIRNNETMYKAGQKELTFLKRLMEAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NDL8</accession>
    <name>A0A1C7NDL8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Glutathione S-transferase omega-2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">Gsto2</name>
        <name evidence="5" type="ORF">A0J61_06474</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000392">
        <property type="protein sequence ID" value="OBZ85474.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NDL8"/>
    <dbReference type="STRING" id="101091.A0A1C7NDL8"/>
    <dbReference type="InParanoid" id="A0A1C7NDL8"/>
    <dbReference type="OrthoDB" id="202840at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045174">
        <property type="term" value="F:glutathione dehydrogenase (ascorbate) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004364">
        <property type="term" value="F:glutathione transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00570">
        <property type="entry name" value="GST_N_family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.30.10:FF:000123">
        <property type="entry name" value="Glutathione transferase o1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1050.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010987">
        <property type="entry name" value="Glutathione-S-Trfase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036282">
        <property type="entry name" value="Glutathione-S-Trfase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040079">
        <property type="entry name" value="Glutathione_S-Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004045">
        <property type="entry name" value="Glutathione_S-Trfase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005442">
        <property type="entry name" value="GST_omega"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050983">
        <property type="entry name" value="GST_Omega/HSP26"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43968">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43968:SF6">
        <property type="entry name" value="GLUTATHIONE S-TRANSFERASE OMEGA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13410">
        <property type="entry name" value="GST_C_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13417">
        <property type="entry name" value="GST_N_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01625">
        <property type="entry name" value="GSTRNSFRASEO"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00019">
        <property type="entry name" value="Glutathione_Transferase_(cytos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG00358">
        <property type="entry name" value="Main_(cytGST)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47616">
        <property type="entry name" value="GST C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51354">
        <property type="entry name" value="GLUTAREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50405">
        <property type="entry name" value="GST_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50404">
        <property type="entry name" value="GST_NTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="GST N-terminal" evidence="3">
        <location>
            <begin position="3"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="domain" description="GST C-terminal" evidence="4">
        <location>
            <begin position="86"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="114"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OBZ85474.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="223" mass="25701" checksum="AE5952C7985816F6" modified="2016-11-30" version="1">MTDKLVLYNAPVCPYAQRAYIALKEVGAEFDLVDIDLLNKPDWYKDVNPELKVPVLKIDGYNLAESMVIVEYINDRYPEKNLLPKDPLKRAQIRFAIEYFSSKVTPEFYKFLMNIKAENARADYEKNINQALTRFDELLKEQSATGPYFLGEEFSLADIAIAPFVFRIHAINNVLLDGLKLETVTSSSRLTEYIKGLLTRPSVKDTWIGEEELVGFMKKRFNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NDT9</accession>
    <name>A0A1C7NDT9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">NADPH:adrenodoxin oxidoreductase, mitochondrial</fullName>
            <ecNumber evidence="8">1.18.1.6</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">fdxr</name>
        <name evidence="12" type="ORF">A0J61_05228</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7 8">
            <text>2 reduced [adrenodoxin] + NADP(+) + H(+) = 2 oxidized [adrenodoxin] + NADPH</text>
            <dbReference type="Rhea" id="RHEA:42312"/>
            <dbReference type="Rhea" id="RHEA-COMP:9998"/>
            <dbReference type="Rhea" id="RHEA-COMP:9999"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33737"/>
            <dbReference type="ChEBI" id="CHEBI:33738"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.18.1.6"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 8 9">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the ferredoxin--NADP reductase type 1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.18.1.6" evidence="8"/>
    <dbReference type="EMBL" id="LUGH01000277">
        <property type="protein sequence ID" value="OBZ86726.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NDT9"/>
    <dbReference type="FunCoup" id="A0A1C7NDT9">
        <property type="interactions" value="513"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NDT9"/>
    <dbReference type="InParanoid" id="A0A1C7NDT9"/>
    <dbReference type="OrthoDB" id="333024at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008860">
        <property type="term" value="F:ferredoxin-NAD+ reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004324">
        <property type="term" value="F:ferredoxin-NADP+ reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006879">
        <property type="term" value="P:intracellular iron ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006744">
        <property type="term" value="P:ubiquinone biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023753">
        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055275">
        <property type="entry name" value="Ferredox_Rdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021163">
        <property type="entry name" value="Ferredox_Rdtase_adrenod"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48467">
        <property type="entry name" value="GLUTAMATE SYNTHASE 1 [NADH], CHLOROPLASTIC-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48467:SF1">
        <property type="entry name" value="GLUTAMATE SYNTHASE 1 [NADH], CHLOROPLASTIC-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000362">
        <property type="entry name" value="FNR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00419">
        <property type="entry name" value="ADXRDTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51971">
        <property type="entry name" value="Nucleotide-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 8 9" id="KW-0274">FAD</keyword>
    <keyword evidence="3 8" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="8" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5 8 10" id="KW-0521">NADP</keyword>
    <keyword evidence="6 8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD/NAD(P)-binding" evidence="11">
        <location>
            <begin position="17"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="27"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="56"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="92"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="168"/>
            <end position="171"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="212"/>
            <end position="213"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="224"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="377"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="384"/>
            <end position="386"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="384"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008312"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00048933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRNR" id="PIRNR000362"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR000362-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR000362-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF07992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="OBZ86726.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="475" mass="52632" checksum="59F05F3312E101BE" modified="2016-11-30" version="1">MTVLSRAFSTVVTNQPFKLAIVGSGPAGFYTAHRLLKECPNAQVDMFDSLPVPHGLVRFGVAPDHPEVKNVMTTFDKVAEDDRFRFLGNVPIGTQSKQSLSIQELQAHFDAILLSYGASEDRKMGIPGESSYGVESARSFVGWYNGHPNFKQLQLPLDETDTAVVIGQGNVALDIARVLLTPVDELRKTDMTEYALEALSKSRIRHVHVVGRRGPVQVSFTSKELREQMAIPDVQFNADMDLIRQEIEASQPLISKNRPLKRLMALLEKGSPTKQGSKSWTAQFLRSPKEILSQDNRVRGIRYEINRLEGPLEHRKAVGTGEHETQSCGLVLTSIGYRSVPIEGIPFDTRQGRVPNSFGKVIDEHGSELAGLYTAGWLKRGPTGVIVSTMADAYETADTILDDLKHQKPMLAGSSKQGADGLTSLLRERHMVPVSYQDWKKIEAAEFALGKQLGKPREKFSTVQDMLAVLEQKKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NE39</accession>
    <name>A0A1C7NE39_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Phosphatidylcholine-sterol acyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">GCAT_1</name>
        <name evidence="3" type="ORF">A0J61_04571</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000227">
        <property type="protein sequence ID" value="OBZ87373.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NE39"/>
    <dbReference type="STRING" id="101091.A0A1C7NE39"/>
    <dbReference type="InParanoid" id="A0A1C7NE39"/>
    <dbReference type="OrthoDB" id="1600564at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016746">
        <property type="term" value="F:acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016788">
        <property type="term" value="F:hydrolase activity, acting on ester bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01846">
        <property type="entry name" value="fatty_acyltransferase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1110">
        <property type="entry name" value="SGNH hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001087">
        <property type="entry name" value="GDSL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050592">
        <property type="entry name" value="GDSL_lipolytic_enzyme"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036514">
        <property type="entry name" value="SGNH_hydro_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45642">
        <property type="entry name" value="GDSL ESTERASE/LIPASE EXL3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45642:SF139">
        <property type="entry name" value="SGNH HYDROLASE-TYPE ESTERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00657">
        <property type="entry name" value="Lipase_GDSL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52266">
        <property type="entry name" value="SGNH hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008889643" evidence="2">
        <location>
            <begin position="21"/>
            <end position="287"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ87373.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="287" mass="32406" checksum="2FC43496A8DD0B88" modified="2016-11-30" version="1">MKLLSLVSVSLVTLTATVSAFDRIIAYADSFTDNGNDYRNSQFPPSPPSYKGRFSNGPTWLEYVAKNLPEHAVINNGYGGATANNDDVYTKFNGYVVPGLIQQIETIPVNGTSKDLYVIYIGYNDLAHILKIGQYYVNNQHYDKEKLAENIVTAVKKLVKKYDAKQFLILNVPPFEQWPATPADKKAYNRKYINDYNALVERQLKKKVKGVDLKFLDDHSWFDEQLALPERLGLSTTNGPCSYGIGNTTTCSDPTKHFFWDSYHPEAKVHKALGGWATEQIKSLYKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NE45</accession>
    <name>A0A1C7NE45_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_04603</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000228">
        <property type="protein sequence ID" value="OBZ87361.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NE45"/>
    <dbReference type="InParanoid" id="A0A1C7NE45"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12937">
        <property type="entry name" value="F-box-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="1">
        <location>
            <begin position="1"/>
            <end position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ87361.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="712" mass="82295" checksum="28FE60B0B2172D2F" modified="2016-11-30" version="1">MASILSLPTETLFQIFGYLWKGDKISCMLVCKRFYPIALKNCFSQVRVDVHSKEYVIPKNAEQRKRCQLLAPDIDCLTISNKDFACDEHYTAEELMEVFSLYKYAEYIYVRSLTDVHTLCRVPKVGALKHMKTIGFCCSLEEPFDTRYTMKRPCYSAQMELMYHFRNSLISAIIIYFDMPPTLPKQPIHSYLADFDRLTRLSFQDEHTSPVTLFGILHACPHLESIEYISYKDQCPETLQLAEAELGELKAKQPKPEANRPTSIYPGLRLKSISLMVSTFPPIYIRFLNDYIRPGVERCELTLLRGDLFTWIASVGESSVLHLMNHMSNVPHASLIARPEDDDNDFLLEIPLPEWDIDTFFRLAHALKGNREVVVEFTLSDGCDLETSLSVSSNYQMILEFPVDLDVTPFYENDILEGIWPENYNPWLMDQEDLEPWDEDERHTDYMDRIYRRFLEPEHPGFGMIHEFNWYTSRNVFAIPTSLVMHVISKCPELRKMKLENHQSLSIVVKEGSWPNSPSKQDMLDLPTLRTGRPEVYIAGRSKYTTEHLYLITKFFPNIKKISLSDAFHALCREPPETPFSNSTFVVNSKALEEFEAELCVRKVGVGAKDIPNLEEQEGVDHTAVVLLHDHETIGRFTVHHERNADGKMVPKATEHDMSEEDFYSAFSDHAVNPGAMSYTILYFEHLPKSIKLQYCWEPVITWSKEKSISLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NEE7</accession>
    <name>A0A1C7NEE7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">DOT1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">A0J61_04479</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ANT/ATPSC lysine N-methyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000220">
        <property type="protein sequence ID" value="OBZ87471.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NEE7"/>
    <dbReference type="STRING" id="101091.A0A1C7NEE7"/>
    <dbReference type="InParanoid" id="A0A1C7NEE7"/>
    <dbReference type="OrthoDB" id="66144at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031151">
        <property type="term" value="F:histone H3K79 methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:1905706">
        <property type="term" value="P:regulation of mitochondrial ATP synthesis coupled proton transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025789">
        <property type="entry name" value="DOT1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026170">
        <property type="entry name" value="FAM173A/B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13610">
        <property type="entry name" value="METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13610:SF11">
        <property type="entry name" value="METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08123">
        <property type="entry name" value="DOT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="DOT1" evidence="5">
        <location>
            <begin position="48"/>
            <end position="167"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010633"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF08123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OBZ87471.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="193" mass="21399" checksum="B6E374A09567C31D" modified="2016-11-30" version="1">MTKQESLFLKVFQNADHQIEDESAEDPFPAYLDDVDTTLAPFCPTSANRVLKALQMANVGPQDILVDLGSGDGRFVTAAVAEFNAQKAVGIESDHELVETSERLAQQVLSTNYSKASFILGDLLDLPNIVHNTNWTVIVLFLLPDHTDKFADMLLQHYRNGARIVSLVFNLNEIPELKLVASDESDGIYVYSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NEF7</accession>
    <name>A0A1C7NEF7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Septum-promoting GTP-binding protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">spg1</name>
        <name evidence="2" type="ORF">A0J61_04465</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000219">
        <property type="protein sequence ID" value="OBZ87483.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NEF7"/>
    <dbReference type="FunCoup" id="A0A1C7NEF7">
        <property type="interactions" value="382"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NEF7"/>
    <dbReference type="InParanoid" id="A0A1C7NEF7"/>
    <dbReference type="OrthoDB" id="6585768at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035974">
        <property type="term" value="C:meiotic spindle pole body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044732">
        <property type="term" value="C:mitotic spindle pole body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035591">
        <property type="term" value="F:signaling adaptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0040001">
        <property type="term" value="P:establishment of mitotic spindle localization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:1904750">
        <property type="term" value="P:negative regulation of protein localization to nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031536">
        <property type="term" value="P:positive regulation of exit from mitosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140281">
        <property type="term" value="P:positive regulation of mitotic division septum assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0023056">
        <property type="term" value="P:positive regulation of signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902542">
        <property type="term" value="P:regulation of protein localization to mitotic spindle pole body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031028">
        <property type="term" value="P:septation initiation signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001806">
        <property type="entry name" value="Small_GTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47978">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00071">
        <property type="entry name" value="Ras"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00449">
        <property type="entry name" value="RASTRNSFRMNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00175">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00174">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51419">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ87483.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="155" mass="17564" checksum="401BC206592E2FA9" modified="2016-11-30" version="1">MEKTVVIRQTEITFSIWDLGGQKEFASMMPLVCGDAVAILFTFDLARKSTLNNLREWYRQARGLNKSAIPVLVGTKYDEFVDLAYEDQDEITRQARSNARKYSRAMKAPLVFCSTAESINVQKIYKIVLAKVFDLTCTLPEVSDIGGPIVEYKHC</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NFB4</accession>
    <name>A0A1C7NFB4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Disintegrin and metalloproteinase domain-containing protein B</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">ADM-B_1</name>
        <name evidence="10" type="ORF">A0J61_04149</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Probable zinc protease.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000196">
        <property type="protein sequence ID" value="OBZ87803.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NFB4"/>
    <dbReference type="FunCoup" id="A0A1C7NFB4">
        <property type="interactions" value="49"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NFB4"/>
    <dbReference type="InParanoid" id="A0A1C7NFB4"/>
    <dbReference type="OrthoDB" id="5951731at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007229">
        <property type="term" value="P:integrin-mediated signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="4.10.70.10:FF:000003">
        <property type="entry name" value="Disintegrin and metalloproteinase domain-containing protein 17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.390.10">
        <property type="entry name" value="Collagenase (Catalytic Domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.70.10">
        <property type="entry name" value="Disintegrin domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001762">
        <property type="entry name" value="Disintegrin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036436">
        <property type="entry name" value="Disintegrin_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024079">
        <property type="entry name" value="MetalloPept_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001590">
        <property type="entry name" value="Peptidase_M12B"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11905">
        <property type="entry name" value="ADAM A DISINTEGRIN AND METALLOPROTEASE DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11905:SF159">
        <property type="entry name" value="ADAM METALLOPROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00200">
        <property type="entry name" value="Disintegrin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13688">
        <property type="entry name" value="Reprolysin_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00050">
        <property type="entry name" value="DISIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57552">
        <property type="entry name" value="Blood coagulation inhibitor (disintegrin)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55486">
        <property type="entry name" value="Metalloproteases ('zincins'), catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50215">
        <property type="entry name" value="ADAM_MEPRO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50214">
        <property type="entry name" value="DISINTEGRIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="10" id="KW-0401">Integrin</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008889663" description="Disintegrin and metalloproteinase domain-containing protein B" evidence="7">
        <location>
            <begin position="23"/>
            <end position="777"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="669"/>
            <end position="694"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M12B" evidence="9">
        <location>
            <begin position="246"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="domain" description="Disintegrin" evidence="8">
        <location>
            <begin position="486"/>
            <end position="571"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="745"/>
            <end position="777"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="746"/>
            <end position="759"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="766"/>
            <end position="777"/>
        </location>
    </feature>
    <feature type="active site" evidence="4">
        <location>
            <position position="403"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="402"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="406"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="412"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="unsure residue" description="E or Q" evidence="10">
        <location>
            <position position="261"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00056552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00074021"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00276"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50214"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50215"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OBZ87803.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="777" mass="86006" checksum="0C6C9AF76CC01085" modified="2016-11-30" version="1">MSNFILLCTLVVLVVLPNFSLGYHTQLNNLESLTDIKVDIIPRSKTFFQKRQQSPNFELSPKKLAFDDHLRITLKAYNQTIHLYLEPNLDLFHPEAAVVVDQQSVQRIHDQPYHQRPLVYKGVAKADHSDQELGWARIIVRDDLIRSHDEQPMIEGAFQFNHDLFHIKTTTTYNLVKRSTDMEPVQPGKMVIYRDSDTTPLTKRGQHHQCGFDNLLHASNPTMSSLMKRGEVFFSQNKPSGCPSTRKITYMGAAADCTYVEYYKNVNNARIQIINNFNMASALFESTFNVSLGLINITIMDTSCPSKIDPDLAWNRPCDATYALNDRLSDFSRWRSRMKGDGAGLWHLMTNCPTGVEVGLAWLKQLCNSGAELQISSEGKHQYVSGAGVSAITREEWKVVAHEIGHGFGAIHDCSATDCSCEGPNCSCCKSEGDQCQTTGYMMSAISNSSAQTFSPCSVRTICNAFPDIGQCLTNLDDHHRSVYQLDSCGNGVREEGEECDTGGEDTACCDAKTCKLKKDAVCEDKTDGCCHNCQIRPKTHVCRPAATACDVSEYCTGESPICPTDKYLRDGLSCGLNGLKCASGQCTSRNEQCLSRGFVMNITQSCRTNNEECKLLCNSPDSSKCLVFSGNFIDGTPCGFGGRCHDGVCRNGGAVGSSILYLREHLHVAIPISLIVFMMASAIGYILFCYGCGRCPGYKERQKRKEYYSNELQAGFFEKRSISILSRLSFSTFMGGEKGSIDLDSPTSTVISPTTSPILTASVPTDEHSTKTQKHE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-06-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NFB8</accession>
    <name>A0A1C7NFB8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_04300</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000207">
        <property type="protein sequence ID" value="OBZ87650.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NFB8"/>
    <dbReference type="InParanoid" id="A0A1C7NFB8"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ87650.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="66" mass="7938" checksum="C91FC9D7AC7B16A3" modified="2016-11-30" version="1">MTELLPEDISICYLAIFFRKLGVGINQLYEARLSTNVMSPHLRMLDEHRHSQIERLLQNLHYRREQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NG52</accession>
    <name>A0A1C7NG52_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Ankyrin repeat domain-containing protein 40</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">Ankrd40</name>
        <name evidence="2" type="ORF">A0J61_04408</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000215">
        <property type="protein sequence ID" value="OBZ87536.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NG52"/>
    <dbReference type="STRING" id="101091.A0A1C7NG52"/>
    <dbReference type="InParanoid" id="A0A1C7NG52"/>
    <dbReference type="OrthoDB" id="539213at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039195">
        <property type="entry name" value="ANKRD40"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24192">
        <property type="entry name" value="ANKYRIN REPEAT DOMAIN 40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24192:SF3">
        <property type="entry name" value="ANKYRIN REPEAT DOMAIN 40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="repeat" description="ANK" evidence="1">
        <location>
            <begin position="40"/>
            <end position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ87536.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="251" mass="27544" checksum="4F671A4C2D8A13D0" modified="2016-11-30" version="1">MPLGDEREHTLREVAALGNIKATLHLAHSGVNVNSQNAMNGWTALHWAAHRGHEHVVTALLRSGADPLIKTQKGQTALDLAAHHPPVIEILQTAVSESDAAILVGPEPSLPIVPTYLSNPDLEKTWLMPDEFSENKIENVVRKQTAAEAVNNNTTTTHSSAPSVSHQEKEVLVYLSKREDENILGSVFLRNESIEKAVEAIKEELDGLPENFTLARHNGKISIPINTKQMSKQLLDIFRGEEDALVIVPQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NGJ4</accession>
    <name>A0A1C7NGJ4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF8032 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_03794</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000171">
        <property type="protein sequence ID" value="OBZ88165.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NGJ4"/>
    <dbReference type="STRING" id="101091.A0A1C7NGJ4"/>
    <dbReference type="InParanoid" id="A0A1C7NGJ4"/>
    <dbReference type="OrthoDB" id="5599902at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058345">
        <property type="entry name" value="DUF8032"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22949:SF0">
        <property type="entry name" value="RE27538P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22949">
        <property type="entry name" value="WHITE COLLAR 2 PROTEIN WC2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26087">
        <property type="entry name" value="DUF8032"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF8032" evidence="2">
        <location>
            <begin position="83"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="domain" description="DUF8032" evidence="2">
        <location>
            <begin position="228"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="44"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="191"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="55"/>
            <end position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF26087"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ88165.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="530" mass="60007" checksum="713980C3925675E8" modified="2016-11-30" version="1">MLHSPTSLSLQDLISAPAKAELLLEHLTADQIVAIEQTLGRVKKRRLDKDRSTHTKATTKSESTRQTNNTPNEPVTEIRDGVEWVSFVYSHNRTLKRYSIRTDLQQVDISLMSDAFKSDNCVYPRANLPKEEYTGNRWAYETECNVLGWKLAWLNKDEIAGKRGLIQRAVDSYRNRYPSMRSRRVARQEKLLNGTLRKRKHREGDEETQDNTSSLSGIAPPTHHPKTIAIEDANHQRFRIKINVESVDLEEINIEFRKANCPFPRAMNMTKPTINSTRWSEETMCNELAWKLAWLNPRHLAGKKNMLQRALDIYRSKFMPSLQPRKNAKRVAPIPPPSLTDTLSQHTSLMDLIPSKEPLTEDALLAQNAMYETTATPSLSSPISTSGTTESLDFNDCFSLADEESIKATDAPMDLTENALFCDVLLQEPLSLIDTFNPIRDSNGRMNSTTSSVSDSTVCTPSPTMTLAADPSFQHDYFDQFMITEEDPFYHSMFSDSTITTSSTAEQLSKLYNASIDDAFSSSHLLDPLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NGM5</accession>
    <name>A0A1C7NGM5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_03698</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000164">
        <property type="protein sequence ID" value="OBZ88253.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NGM5"/>
    <dbReference type="InParanoid" id="A0A1C7NGM5"/>
    <dbReference type="OrthoDB" id="2289244at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ88253.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="228" mass="26284" checksum="2438DC790D858D44" modified="2016-11-30" version="1">MAQHQANNNNNSQNGLLGNGPMDWLTNAATFAGVDALLNRYDEENEDKAHFWRNAGLAGALALGYQYYRDHHNRPQPIAIDNEQQQQIIAQQSQPVNTGMPYAPYYYPPPQQPLDYNYGSSYQNAMIPSQPPYFGPPMMPPLMPYNTMGYNMPMMPQDPYMMMITNHMMQQQQQQQMQMQMQQQYGGMPFQNYGLPPFAVNPNMGQMPMVPYSVQHHHLFGHHRPSYF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NGZ1</accession>
    <name>A0A1C7NGZ1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">sn-1-specific diacylglycerol lipase</fullName>
            <ecNumber evidence="14">3.1.1.116</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">A0J61_04140</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>a 1,2-diacyl-sn-glycerol + H2O = a 2-acylglycerol + a fatty acid + H(+)</text>
            <dbReference type="Rhea" id="RHEA:33275"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17389"/>
            <dbReference type="ChEBI" id="CHEBI:17815"/>
            <dbReference type="ChEBI" id="CHEBI:28868"/>
            <dbReference type="EC" id="3.1.1.116"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="13">
            <dbReference type="Rhea" id="RHEA:33276"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.116" evidence="14"/>
    <dbReference type="EMBL" id="LUGH01000196">
        <property type="protein sequence ID" value="OBZ87806.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NGZ1"/>
    <dbReference type="InParanoid" id="A0A1C7NGZ1"/>
    <dbReference type="OrthoDB" id="438440at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016298">
        <property type="term" value="F:lipase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019369">
        <property type="term" value="P:arachidonate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046340">
        <property type="term" value="P:diacylglycerol catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00519">
        <property type="entry name" value="Lipase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052214">
        <property type="entry name" value="DAG_Lipase-Related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002921">
        <property type="entry name" value="Fungal_lipase-type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45792">
        <property type="entry name" value="DIACYLGLYCEROL LIPASE HOMOLOG-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45792:SF7">
        <property type="entry name" value="PUTATIVE (AFU_ORTHOLOGUE AFUA_6G02710)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01764">
        <property type="entry name" value="Lipase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-0106">Calcium</keyword>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-0442">Lipid degradation</keyword>
    <keyword evidence="11" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="12" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="Fungal lipase-type" evidence="16">
        <location>
            <begin position="702"/>
            <end position="803"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="412"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="469"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="507"/>
            <end position="535"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="15">
        <location>
            <begin position="436"/>
            <end position="453"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022963"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00024531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00026104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF01764"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="OBZ87806.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="1051" mass="117470" checksum="181A3B9ECFEA4B1D" modified="2016-11-30" version="1">MVMSTEIATYAAGIYNSTSPTLLPENIASFITAIALATRLSLRCSSLLIEVLMESVKYSTSLSFGISRQAIINALSSAKKLHELSSKALVASTDTVVNTENHGFLQILDKYTNLGIYLVHHSFTLAELFTLSGIQFTTQTIKSGLKAAEESVGIIDGIFGSNESSRAIASIITLVHREVMNDPEFALTKIGKVAILSGLTKAMTAFAVLQNVTHRRTMKQMKNVVLWKGLVIEEKENSQALLEYNHHPHASEKHSDVIHELEEILANTSSNMHDASEHQESHSSLISLSSASNDLNGKPIDLSLDKNGNPYHMYEITTITNQTTTRTTRIRPIDAYGNQRVATKQVIQTTNEEENESFIAVVDHQPQMPYCQDHEQHIVPFRHNTTMADTKNSQTGFKIMLSSVSKKLARKKLERKTTYSSHQEDENSEETIDGPIQTSTSTTYQHQESSSTQYISCKQDKAISLTDTEDDISAYSEPETKPKRRMSWSGLKMKQIRKKKSITNLFQKGTQGSQSDSKKRKAFKPEVVPPMPSPNKYNGIYLQSKKNNNLSSSSSIAHTFKTLTYSEETPSIASNTSSRSLVRSPSVPSCIHQANSLLESEPNQQNFPRRHIVTNIAHFIRYASAAYGESFMRILGIGDIPSVLPNSHHPNHHAFAHHTGVAVEDILLSSYTDTNILSSVTHSKLHALVHYVTVDHQAEAIVLTCRGTLGLSDVLTDLTCDYKEFTLPVDQLPHGDEANGGQKRHYIAHGGMLEAAQLLATQKGKVFEAIKLGLERYPDYGLVLCGHSLGAGVASLLSVLWSEERLHFLSRRMMTHQDKHQSRLLDSFATDSIKRLGCPFVTSELSGLPAGRPIHCYTYGSPCVMSLPLSEYCGQGLVTSVVHAFDIVSSLSLGLLRDFKNIAVSLHEESHVADEILSRVIGHYQTKKKEPKKKNSMEHGCQKEEQEEEDEQWFWALIKTMRADMRAEKLFPPSTIYLIESVPQLVRRTVSTQADRRELKHKMAHMVRFSRCDDVQARFSEIVFSRTMFMDHSPNMYEKTIRQLNKGFFGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NH92</accession>
    <name>A0A1C7NH92_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Kinesin-like protein KIF21B</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">KIF21B_1</name>
        <name evidence="10" type="ORF">A0J61_03468</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000150">
        <property type="protein sequence ID" value="OBZ88483.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NH92"/>
    <dbReference type="FunCoup" id="A0A1C7NH92">
        <property type="interactions" value="698"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NH92"/>
    <dbReference type="InParanoid" id="A0A1C7NH92"/>
    <dbReference type="OrthoDB" id="3176171at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005875">
        <property type="term" value="C:microtubule associated complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008017">
        <property type="term" value="F:microtubule binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003777">
        <property type="term" value="F:microtubule motor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007018">
        <property type="term" value="P:microtubule-based movement"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007052">
        <property type="term" value="P:mitotic spindle organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051231">
        <property type="term" value="P:spindle elongation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.850.10">
        <property type="entry name" value="Kinesin motor domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027640">
        <property type="entry name" value="Kinesin-like_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019821">
        <property type="entry name" value="Kinesin_motor_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001752">
        <property type="entry name" value="Kinesin_motor_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036961">
        <property type="entry name" value="Kinesin_motor_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47969">
        <property type="entry name" value="CHROMOSOME-ASSOCIATED KINESIN KIF4A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47969:SF15">
        <property type="entry name" value="CHROMOSOME-ASSOCIATED KINESIN KIF4A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00225">
        <property type="entry name" value="Kinesin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00380">
        <property type="entry name" value="KINESINHEAVY"/>
    </dbReference>
    <dbReference type="SMART" id="SM00129">
        <property type="entry name" value="KISc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00411">
        <property type="entry name" value="KINESIN_MOTOR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50067">
        <property type="entry name" value="KINESIN_MOTOR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0505">Motor protein</keyword>
    <keyword evidence="3 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Kinesin motor" evidence="9">
        <location>
            <begin position="10"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="133"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="257"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="989"/>
            <end position="1051"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="460"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="519"/>
            <end position="581"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="649"/>
            <end position="762"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="792"/>
            <end position="819"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="897"/>
            <end position="924"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="259"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="998"/>
            <end position="1012"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="1018"/>
            <end position="1033"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="89"/>
            <end position="96"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00283"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50067"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OBZ88483.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="1147" mass="129837" checksum="F65943865ABB68F9" modified="2016-11-30" version="1">MKDTQGQVAAVQVAIRVRPLTERDRSQRFSAEVLRAQERHIQVIPQNKYFHYDHVFGPETHQSDIFASLGEKPVQKFVEGYNVTMLAYGQTSSGKTYTMGTAQHTDATDPEQDGIVPRAMALLFSLLQQQQQSELPTPTSPRSGLRPVSQIGNSNASQKYRYSVKVSFVEIYNEDLIDLLNPALPSEKPPVTIREDTKGHIYWTGVKEVTVHNTDDVLYFLQQGTENRATGFTDMNAKSSRSHAIFSVTLKQERFVSGASPQSSRAASPTASKLQQKRLSPARPPTNEDGDWVITSSKFHFVDLAGSERLKRTAAEGDRRKEGININAGLLALGNVISALGDPSKKSTHVPYRDSKLTRLLQDSLGGSAMTLMIACVSPAESNLSETLNTLQYANRARNIKNKMEKNEMEEWMTTDNLDFLRTTISKLKNELRTNKAASPSKSGLQLEGDTSPEFDEEVYHQQHAIIADLQQQVEELQGAAEFIKGRNVVVENELVRLRQERTAAASDFDFQHLVEPVIEEYEKSISGLESQLAMIRAALSHSDQGFEEQQAKIEQLEIVIESQEKTIGELRRRVSKLLERRLKDETYIAELEKKLMTAVEETVRDREMLSELRGKILKLKEVDENTEEYIHDLEGRLTASEAERLLLKEKLNDMMNSAKVELQGNNEEKRMVNQEHEKQLQELTEKHDAAEKERHRLQAQVDQLLSQSTLQGQNENLENAVKTQNEMKAKDYRIKDLESDLANLQHEHQETLKELDEVLLRYQEALEHAEHPPTLPVSDIKPNTPSSDEEVQLLRQSIQHLEQELDMASRRESILRQLSEDHHESVQVEKTLEKLEIQDTSRHASDFDHSEFILQSIDTLQKKYEHLRTKMQIQSIHIETDNEDDLQELHSMADFRASYESQILAYKREIKNLTRIMKDIKRIRSNETKTAITTHPEHRILMKSVVGLDKQLTEQYEKMKLEAKRFASDISEMISANSGLENELATMNPTASEGTQSGSSSVPSSPRVRNSMIRPPTNFSTGSTGSNRSSIVNMMPGHDDQSSVSSDIVLPSPSSSSLIHQYEKNGLAIQTRLSIAKQDLKTHQTVIHALELKFKSIDIALNTCKKRMEGGASSVTDVEIEELMSKMDAMQIQLETNERKSAAVMD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-06-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NH99</accession>
    <name>A0A1C7NH99_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_05201</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000275">
        <property type="protein sequence ID" value="OBZ86744.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NH99"/>
    <dbReference type="InParanoid" id="A0A1C7NH99"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ86744.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="73" mass="8232" checksum="C2BD92A8A833CFD9" modified="2016-11-30" version="1">MCISPTPQCLHQAQPNQYSDHETELISHNTNNLSYQAFIAGASTMSKLKTLQHWLSYRQILTQGGLLIKTDSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NHY6</accession>
    <name>A0A1C7NHY6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative tubulin--tyrosine ligase PBY1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">PBY1</name>
        <name evidence="2" type="ORF">A0J61_03324</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000140">
        <property type="protein sequence ID" value="OBZ88628.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NHY6"/>
    <dbReference type="STRING" id="101091.A0A1C7NHY6"/>
    <dbReference type="InParanoid" id="A0A1C7NHY6"/>
    <dbReference type="OrthoDB" id="202825at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000932">
        <property type="term" value="C:P-body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1210.10">
        <property type="entry name" value="Survival protein SurE-like phosphatase/nucleotidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002828">
        <property type="entry name" value="SurE-like_Pase/nucleotidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036523">
        <property type="entry name" value="SurE-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027746">
        <property type="entry name" value="TTL"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00087">
        <property type="entry name" value="surE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47551">
        <property type="entry name" value="TUBULIN--TYROSINE LIGASE PBY1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47551:SF1">
        <property type="entry name" value="TUBULIN--TYROSINE LIGASE PBY1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01975">
        <property type="entry name" value="SurE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64167">
        <property type="entry name" value="SurE-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0436">Ligase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Survival protein SurE-like phosphatase/nucleotidase" evidence="1">
        <location>
            <begin position="4"/>
            <end position="225"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ88628.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="295" mass="33522" checksum="36C1B9633F5D108E" modified="2016-11-30" version="1">MRVLISNDDGKLIYEFLAFVCIQAHAYVITGPPSWEESPFILPFVEHLESLGWDVKVCLPDSQKSWIAKSFLIKDDIQLRYYNRSTQQITTEQQDKTDFLLLTGTPATCVNIALHHLFADQEFDLVISGPNFGRNFSNLFTLASGTVGAAMEGALNKKKAISISFCFSNKQPECIQNCCETASDIVQHLYRLDMPWPTLGVFNVNIPMTKERRPVHMTKFYNTHYGSLFKQDKHGHFHFKPDFSNTHQDPGVEGTDQWALMNKYVSITPMVAALQTAHVDDLDFDVDSLNTKVFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NJK7</accession>
    <name>A0A1C7NJK7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Autophagy-related protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">ATG22</name>
        <name evidence="8" type="ORF">A0J61_02643</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Vacuolar effluxer which mediate the efflux of amino acids resulting from autophagic degradation. The release of autophagic amino acids allows the maintenance of protein synthesis and viability during nitrogen starvation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="7">Vacuole membrane</location>
            <topology evidence="7">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the ATG22 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000102">
        <property type="protein sequence ID" value="OBZ89301.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NJK7"/>
    <dbReference type="FunCoup" id="A0A1C7NJK7">
        <property type="interactions" value="4"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NJK7"/>
    <dbReference type="InParanoid" id="A0A1C7NJK7"/>
    <dbReference type="OrthoDB" id="192733at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005774">
        <property type="term" value="C:vacuolar membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006865">
        <property type="term" value="P:amino acid transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006914">
        <property type="term" value="P:autophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024671">
        <property type="entry name" value="Atg22-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050495">
        <property type="entry name" value="ATG22/LtaA_families"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23519">
        <property type="entry name" value="AUTOPHAGY-RELATED PROTEIN 22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23519:SF1">
        <property type="entry name" value="AUTOPHAGY-RELATED PROTEIN 22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11700">
        <property type="entry name" value="ATG22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0029">Amino-acid transport</keyword>
    <keyword evidence="7" id="KW-0072">Autophagy</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 7" id="KW-0813">Transport</keyword>
    <keyword evidence="7" id="KW-0926">Vacuole</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="96"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="127"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="153"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="220"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="261"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="317"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="355"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="387"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="481"/>
            <end position="502"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006978"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU363073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OBZ89301.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="519" mass="58662" checksum="E18D23762E0CB552" modified="2016-11-30" version="1">MPFSLNNEKVTSEEVLLEFDQPPATQKELWGYYLYYNGNNGYTIYGFMPIILQYLAYRGGFQPETPDIKGCPLEDTTRPCHVRWIHSPQGIPVSSMLLYLQSIAFSIQFFLFTTFSSLADYGRWNRYILLGSTLIGCVCQALPLALVNDDGSHWYWMMVIMCIGLISYGTSLAFYAAAFPNLSDNLPIVRQARANPCLSEKEKETVVERWRNHISAVSTVFSNIGFLLMSGLLSGISFVPWPYDFPPGVQPVLGNVPLYNFISTAVCAGYWALNAIPYFVWTPKGRKGRPLPKHANHLTLGWLSIIQAIREARKLRYLFMYILAYFMFSDAVSTITQMTTIIQGQLTSFSPQQNVLFGLVTAITSIIGCLLFLWISKTCHIRTKTTLMIILAFTGCIPIWGCFGIGHERFGIRTHHELWVLNIWQGLFTAPIWAWQQTMLAELIPKGKENLFFGLASVVNKASSWIGPVVIGAIAQSTHDLWKGWPFVLGLFVAAMVLVSLIDMDKAKLELIEYEKNLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-06-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NJX3</accession>
    <name>A0A1C7NJX3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_02604</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000100">
        <property type="protein sequence ID" value="OBZ89355.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NJX3"/>
    <dbReference type="InParanoid" id="A0A1C7NJX3"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ89355.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="64" mass="7431" checksum="515B71CC4EE70A3D" modified="2016-11-30" version="1">MCVLSALLRNKILDEYDNKTWILMKHMWLFSGGKHQAIESKDYIIECQIVEAVRYLKATLAVST</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NK03</accession>
    <name>A0A1C7NK03_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">3-hydroxyacyl-CoA dehydrogenase</fullName>
            <ecNumber evidence="4">1.1.1.35</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="primary">HADH</name>
        <name evidence="17" type="ORF">A0J61_02506</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>a (3S)-3-hydroxyacyl-CoA + NAD(+) = a 3-oxoacyl-CoA + NADH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:22432"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57318"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:90726"/>
            <dbReference type="EC" id="1.1.1.35"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Lipid metabolism; fatty acid beta-oxidation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion matrix</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the 3-hydroxyacyl-CoA dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.35" evidence="4"/>
    <dbReference type="EMBL" id="LUGH01000095">
        <property type="protein sequence ID" value="OBZ89447.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NK03"/>
    <dbReference type="STRING" id="101091.A0A1C7NK03"/>
    <dbReference type="InParanoid" id="A0A1C7NK03"/>
    <dbReference type="OrthoDB" id="5958943at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003857">
        <property type="term" value="F:(3S)-3-hydroxyacyl-CoA dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070403">
        <property type="term" value="F:NAD+ binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006635">
        <property type="term" value="P:fatty acid beta-oxidation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000258">
        <property type="entry name" value="Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1040.10">
        <property type="entry name" value="N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022694">
        <property type="entry name" value="3-OHacyl-CoA_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006180">
        <property type="entry name" value="3-OHacyl-CoA_DH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006176">
        <property type="entry name" value="3-OHacyl-CoA_DH_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006108">
        <property type="entry name" value="3HC_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008927">
        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013328">
        <property type="entry name" value="6PGD_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052242">
        <property type="entry name" value="Mito_3-hydroxyacyl-CoA_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43561">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43561:SF3">
        <property type="entry name" value="HYDROXYACYL-COENZYME A DEHYDROGENASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00725">
        <property type="entry name" value="3HCDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02737">
        <property type="entry name" value="3HCDH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000105">
        <property type="entry name" value="HCDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48179">
        <property type="entry name" value="6-phosphogluconate dehydrogenase C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00067">
        <property type="entry name" value="3HCDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="8" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="9" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="7 12" id="KW-0520">NAD</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="3-hydroxyacyl-CoA dehydrogenase NAD binding" evidence="16">
        <location>
            <begin position="29"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="domain" description="3-hydroxyacyl-CoA dehydrogenase C-terminal" evidence="15">
        <location>
            <begin position="218"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="300"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <begin position="34"/>
            <end position="39"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="57"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="73"/>
        </location>
        <ligand>
            <name>CoA</name>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="80"/>
        </location>
        <ligand>
            <name>CoA</name>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="122"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="127"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="149"/>
        </location>
        <ligand>
            <name>CoA</name>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="149"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="175"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="308"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="site" description="Important for catalytic activity" evidence="11">
        <location>
            <position position="172"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004305"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005005"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009463"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013000"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00049556"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR000105-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR000105-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR000105-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF00725"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF02737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="OBZ89447.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="319" mass="35068" checksum="E964C48BD49161F2" modified="2016-11-30" version="1">MFHKQLTRLVNGHYRSFSTSALRFKELNNITVVGAGLMGSGIAQVAAQANCNVTVVDTSNASLENGKTIISRSLQRVARKKFADNEDQQKEYISKVLANIHLTTDANASVRNADLVVEAIVENIETKHKLFESMDQSAPQHTIFCSNTSSLSIRSIADATSPERQKRFAGLHFFNPVPAMKLVEIVRTDRVTREVLQDLNDFAKKIGKTPVACKDTPGFIVNRLLVPYMMEAFRIVDRGEASIPDIDTAMKLGAGMPMGPLELADLVGLDTMKSIVDGWADKKALDPSITQPSPTLEELCAKGDFGRKSGKGFYDYSKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NK08</accession>
    <name>A0A1C7NK08_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_02620</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000101">
        <property type="protein sequence ID" value="OBZ89330.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NK08"/>
    <dbReference type="InParanoid" id="A0A1C7NK08"/>
    <dbReference type="OrthoDB" id="3239304at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="66"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="101"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="175"/>
            <end position="194"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ89330.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="226" mass="26049" checksum="C364E6010A2B8C00" modified="2016-11-30" version="1">MGRSYSDKVCCCIPSRVGVLLVCCIIFSIYLTLTILMFLYEEDLQLWSTAEDEVDNPLTIEAFNGIFTAFAVIFISYSAVSALGILVVFMRRKKWVRVYHVINWFYVLLLFTITVSIWAHFNMDRNNFINTCQIDYNIANNITNHPYYTPLVVPGKQVVAGGSDKSACIDLVRRMLIGSGILVFSCNLIQVYWARTIGKYAIHFKKSFQHKRLETRDEDMMSIHDH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NK87</accession>
    <name>A0A1C7NK87_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Casein kinase II subunit beta</fullName>
            <shortName evidence="3">CK II beta</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">ckb1</name>
        <name evidence="5" type="ORF">A0J61_02388</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 3">Regulatory subunit of casein kinase II/CK2. As part of the kinase complex regulates the basal catalytic activity of the alpha subunit a constitutively active serine/threonine-protein kinase that phosphorylates a large number of substrates containing acidic residues C-terminal to the phosphorylated serine or threonine.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Tetramer of two alpha and two beta subunits.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the casein kinase 2 subunit beta family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000089">
        <property type="protein sequence ID" value="OBZ89552.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NK87"/>
    <dbReference type="FunCoup" id="A0A1C7NK87">
        <property type="interactions" value="515"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NK87"/>
    <dbReference type="InParanoid" id="A0A1C7NK87"/>
    <dbReference type="OrthoDB" id="3971593at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005956">
        <property type="term" value="C:protein kinase CK2 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034456">
        <property type="term" value="C:UTP-C complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004672">
        <property type="term" value="F:protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043539">
        <property type="term" value="F:protein serine/threonine kinase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000122">
        <property type="term" value="P:negative regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090053">
        <property type="term" value="P:positive regulation of pericentric heterochromatin formation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090055">
        <property type="term" value="P:positive regulation of silent mating-type cassette heterochromatin formation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006359">
        <property type="term" value="P:regulation of transcription by RNA polymerase III"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1820.10:FF:000005">
        <property type="entry name" value="Casein kinase II subunit beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.20.25.20:FF:000002">
        <property type="entry name" value="Casein kinase II subunit beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.25.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1820.10">
        <property type="entry name" value="protein kinase ck2 holoenzyme, chain C, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016149">
        <property type="entry name" value="Casein_kin_II_reg-sub_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035991">
        <property type="entry name" value="Casein_kinase_II_beta-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000704">
        <property type="entry name" value="Casein_kinase_II_reg-sub"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11740">
        <property type="entry name" value="CASEIN KINASE II SUBUNIT BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11740:SF39">
        <property type="entry name" value="CASEIN KINASE II SUBUNIT BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01214">
        <property type="entry name" value="CK_II_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00472">
        <property type="entry name" value="CASNKINASEII"/>
    </dbReference>
    <dbReference type="SMART" id="SM01085">
        <property type="entry name" value="CK_II_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57798">
        <property type="entry name" value="Casein kinase II beta subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01101">
        <property type="entry name" value="CK2_BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="215"/>
            <end position="236"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00045899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU361268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OBZ89552.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="236" mass="27801" checksum="1D8C1BB319208D72" modified="2016-11-30" version="1">MSSGSESEYARYWIEWFLETKGNEYFCEVDEDYILDRFNLTGLSAEVPHYYLEALDMITDNLDEEGLDEKVREQIEKSARHLFGLIHARFVITSRGLMKMLDKYKRAEFGRCPRVLCNLQPLLPVGLSDIPMTKTVKLYCPRCEDIYNPKSSRHSAIDGAYFGTSFPHMLFQVHANYLPTKTTERYIPRIFGFKIHEIANQHRWQDQAREQFEAKRKLLQQSEEDEQQQAEEGKNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NKK4</accession>
    <name>A0A1C7NKK4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Protein sel-1 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">Sel1l2</name>
        <name evidence="5" type="ORF">A0J61_02264</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the sel-1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000083">
        <property type="protein sequence ID" value="OBZ89673.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NKK4"/>
    <dbReference type="FunCoup" id="A0A1C7NKK4">
        <property type="interactions" value="130"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NKK4"/>
    <dbReference type="InParanoid" id="A0A1C7NKK4"/>
    <dbReference type="OrthoDB" id="27934at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036503">
        <property type="term" value="P:ERAD pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006597">
        <property type="entry name" value="Sel1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050767">
        <property type="entry name" value="Sel1_AlgK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11102">
        <property type="entry name" value="SEL-1-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11102:SF147">
        <property type="entry name" value="SEL1L ADAPTOR SUBUNIT OF ERAD E3 UBIQUITIN LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08238">
        <property type="entry name" value="Sel1"/>
        <property type="match status" value="11"/>
    </dbReference>
    <dbReference type="SMART" id="SM00671">
        <property type="entry name" value="SEL1"/>
        <property type="match status" value="10"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81901">
        <property type="entry name" value="HCP-like"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008889755" evidence="4">
        <location>
            <begin position="32"/>
            <end position="820"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="775"/>
            <end position="794"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="708"/>
            <end position="764"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="719"/>
            <end position="755"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00038101"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OBZ89673.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="820" mass="93221" checksum="7FFF7B2B3955651A" modified="2016-11-30" version="1">MTRQKQSNCWKKKAICFAPIVLSCLVQFTLASSDQQQVLTTSIEKGTPDYITEGQRLYQEALKQLQLIDQKYTNATSKSTKHHKFSITDRLLQTLLHSWQSKTTTTSLMLSSEKLKELNHLKETELSSATQMLKKAAHDYENNDALLLLAELHFFSKYSHPRNYHHAFGYYHELASKGNATAQQMIGFMYSTGMGNVVPRDQAKALLYHTFAAHGGDTAAEMTLGYRYLMGIGTEETCEDALYHYKRVATKVIDYYLSGPPGGHTPPLSKVRLSEKEGGIYGYGASLTTDKRARHGTGAHEKTVSMEEILQYWRYLAAKQDMDAQLMLGQVYYLGTRSIARNFDEALVFFGQIVDKIPANGKIPSKHGKAIGQAAGYLGLMHWRGEGVPVNPKVAHGWFEIGKRLGDATSQNALGMMYLDGIVVPKNRDKAIELFKKAADQENPHAQVNLAIEYAQTESSMPLAVRLFTKAADAKHLLAYWYLAHLNEQNLAPRPSCRVAVSYYKAIAERGDWLNPTVEEAYQAYKDNDKENALVHYLLAAERGYEVAQSNVAYMLDNDKRMLTHLPWVNMEEEKEESLAMNGLNPQESAFIYWTRSANQNNVDARVKMGDYYFKGIGTTVDYEKAVSCYRLAAEMQGSPLAFWNLGWMYENGVGVAKDFHLAKRAYDHALNIEQDAYLPVKFSLLKMYVKYYWEWMMGHEVGPALDSANDDNMQKPTRNKEVAEGNDRDIGEEMERQYKMKKQKEREEQERLGEDDVFGSDPYGLDDFSEEDELFESLLILSICLLVGYLVYVRQFRFNGNNQQQRENPPPPPPPYNVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NKN3</accession>
    <name>A0A1C7NKN3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Defensin-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_02243</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000082">
        <property type="protein sequence ID" value="OBZ89697.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NKN3"/>
    <dbReference type="InParanoid" id="A0A1C7NKN3"/>
    <dbReference type="OrthoDB" id="2274040at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008889753" description="Defensin-like protein" evidence="1">
        <location>
            <begin position="28"/>
            <end position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ89697.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="109" mass="12002" checksum="520A2F2C4285D719" modified="2016-11-30" version="1">MKSTQLVLYMFATFSTLLLSQSNLVDAKTLDLSDYGLCEVPGDSSDCQFACQEMIQGRGSCIFNKCYCTEKAEIGKCEDDDHESCNALCQDMSPSLVGFCMDDQCNCIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NKX1</accession>
    <name>A0A1C7NKX1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">RING-type E3 ubiquitin transferase</fullName>
            <ecNumber evidence="2">2.3.2.27</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">A0J61_04001</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.</text>
            <dbReference type="EC" id="2.3.2.27"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.27" evidence="2"/>
    <dbReference type="EMBL" id="LUGH01000186">
        <property type="protein sequence ID" value="OBZ87954.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NKX1"/>
    <dbReference type="STRING" id="101091.A0A1C7NKX1"/>
    <dbReference type="InParanoid" id="A0A1C7NKX1"/>
    <dbReference type="OrthoDB" id="8062037at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd16461">
        <property type="entry name" value="RING-H2_EL5-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.40.10:FF:000388">
        <property type="entry name" value="Putative RING zinc finger domain superfamily protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045191">
        <property type="entry name" value="MBR1/2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22937:SF65">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE ARK2C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22937">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE RNF165"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13639">
        <property type="entry name" value="zf-RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="6" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <keyword evidence="5 8" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="10">
        <location>
            <begin position="351"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="234"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="72"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="260"/>
            <end position="269"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="OBZ87954.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="408" mass="45257" checksum="CD5BCD44D7B3459F" modified="2016-11-30" version="1">MGQRQSSQQPNNPQDNTADNNSSSSNISQTQNTPESNRRDRVLRPRPRRSATSNTVPYRLRRERSPDGIASTPDTLFTSQTSSRGDQPITDALETTAATLPPSSTMTTPSHENMSPFSRMIAQVISEAVVASFRNGHIPILPTANRNENEQENNVRQHLTMHLSPDIFQQIEPESTENSFMQFMRLPVIVTSVSRPAESTAVNADGQPPTTTGETELTRVMMLPVFLYGLRTSTTQSASSDTAAEEEAGSDTQPRRQSARIRERLEREQQQQQQPVRGLGSGQWTVYIISGNGIEGMMNDSPSYEDLLDLATFIGPARLPTVSQEAIDNHVPIVKYTQQVKQAMLGNADGCQVCLSNYQSEEDVRILDCHHGFHKECIDKWLTEGQNKCPLCRHQPVPTTHSTTPNAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NL37</accession>
    <name>A0A1C7NL37_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Phosphopantothenate--cysteine ligase CAB2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">CAB2</name>
        <name evidence="3" type="ORF">A0J61_02260</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the PPC synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000082">
        <property type="protein sequence ID" value="OBZ89690.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NL37"/>
    <dbReference type="FunCoup" id="A0A1C7NL37">
        <property type="interactions" value="652"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NL37"/>
    <dbReference type="InParanoid" id="A0A1C7NL37"/>
    <dbReference type="OrthoDB" id="70224at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990143">
        <property type="term" value="C:CoA-synthesizing protein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004632">
        <property type="term" value="F:phosphopantothenate--cysteine ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990181">
        <property type="term" value="P:acetyl-CoA biosynthetic process from pantothenate"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015937">
        <property type="term" value="P:coenzyme A biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10300">
        <property type="entry name" value="CoaB-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035929">
        <property type="entry name" value="CoaB-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007085">
        <property type="entry name" value="DNA/pantothenate-metab_flavo_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12290">
        <property type="entry name" value="CORNICHON-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04127">
        <property type="entry name" value="DFP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102645">
        <property type="entry name" value="CoaB-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0436">Ligase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA/pantothenate metabolism flavoprotein C-terminal" evidence="2">
        <location>
            <begin position="181"/>
            <end position="309"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ89690.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="329" mass="37518" checksum="BD089F19336E9B7E" modified="2016-11-30" version="1">MFAATNTTYEPILDNGQGVIDPDVYFQINQPPADLPEFESKLSAFIDYHKEKQSKVVFITSGGTTVPLENQTVRFIDNFSNGTRGATSAEYFLEAGYAVVFMHRQNSIQPYHRHFIPSSLGFLDYMEPKEDGTVQVRAEYASKMHNVLKKYNHAKQENRILMLEFVTLPEYLFKLQSGTKIFARLQNKAMYYLAAAVSDFFIRSEKMAEHKIQSRDGGLTLTLDQVPKFLKPLVSHWASKGLIVSFKLETDDNLLVPKARQALTRYGHQVVIGNMLKTRKQTVTLITQNNQSVLSLSKDEMDQDVEIESKIIPELVRIHQNWITSGLTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NL78</accession>
    <name>A0A1C7NL78_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Integrase zinc-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_03895</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000178">
        <property type="protein sequence ID" value="OBZ88054.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NL78"/>
    <dbReference type="InParanoid" id="A0A1C7NL78"/>
    <dbReference type="OrthoDB" id="2281046at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.340.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041588">
        <property type="entry name" value="Integrase_H2C2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17921">
        <property type="entry name" value="Integrase_H2C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Integrase zinc-binding" evidence="1">
        <location>
            <begin position="11"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF17921"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ88054.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="98" mass="11541" checksum="103440F7A66F6AED" modified="2016-11-30" version="1">MDESYIISNEGDRKDILKNAHAFEHFGADPMAQRTRKEEGMNWPRILQDTLEITVQCITCQKFVIAKRGYNPLCPLIVTHPYGIIRWIYVVYRMQLIQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NM23</accession>
    <name>A0A1C7NM23_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">1-phosphatidylinositol-4-phosphate 5-kinase</fullName>
            <ecNumber evidence="2">2.7.1.68</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">1-phosphatidylinositol 4-phosphate kinase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">Diphosphoinositide kinase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">PIP5K</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="primary">its3_0</name>
        <name evidence="13" type="ORF">A0J61_03616</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol 4-phosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:14425"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:58178"/>
            <dbReference type="ChEBI" id="CHEBI:58456"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.68"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.68" evidence="2"/>
    <dbReference type="EMBL" id="LUGH01000159">
        <property type="protein sequence ID" value="OBZ88324.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NM23"/>
    <dbReference type="FunCoup" id="A0A1C7NM23">
        <property type="interactions" value="432"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NM23"/>
    <dbReference type="InParanoid" id="A0A1C7NM23"/>
    <dbReference type="OrthoDB" id="20783at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016308">
        <property type="term" value="F:1-phosphatidylinositol-4-phosphate 5-kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046854">
        <property type="term" value="P:phosphatidylinositol phosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd17303">
        <property type="entry name" value="PIPKc_PIP5K_yeast_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.800.10:FF:000009">
        <property type="entry name" value="Phosphatidylinositol 4-phosphate 5-kinase its3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.810.10">
        <property type="entry name" value="2-Layer Sandwich"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.800.10">
        <property type="entry name" value="Phosphatidylinositol Phosphate Kinase II Beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027483">
        <property type="entry name" value="PInositol-4-P-4/5-kinase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002498">
        <property type="entry name" value="PInositol-4-P-4/5-kinase_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027484">
        <property type="entry name" value="PInositol-4-P-5-kinase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023610">
        <property type="entry name" value="PInositol-4/5-P-5/4-kinase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23086:SF8">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL 5-PHOSPHATE 4-KINASE, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23086">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL-4-PHOSPHATE 5-KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01504">
        <property type="entry name" value="PIP5K"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00330">
        <property type="entry name" value="PIPKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56104">
        <property type="entry name" value="SAICAR synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51455">
        <property type="entry name" value="PIPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 11 13" id="KW-0418">Kinase</keyword>
    <keyword evidence="5 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 11" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PIPK" evidence="12">
        <location>
            <begin position="224"/>
            <end position="621"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000444"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00078403"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00080374"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00082306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51455"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="OBZ88324.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="645" mass="74363" checksum="5F3D3D1B7FEA0CE3" modified="2016-11-30" version="1">MSVLENEIAMSPTSASWDFHKNEDIENMAACTATPIVANNQRNHHSIIDNKTLAEEAPVDLSSPPESPAPSVVAVPFLNATEKRSYTIPYIKNPLDVPTPATTPATTPESQRRQYMAQEQPEEQSLKRHSTISSIRTIEEATSETTAPAGTSTVALGRHHTTGHALKTHRQRMADKERLSLMRRSEEFQKELTARRKTFKRLSRLMDPREDAEDDRVMIGTRISEGHQNYVLMYNMLTGIRIAVSRVTAKMYRPLTDEDYTAAHKLAFDVIGDELTPGAKYDFKFKDYAPWVFRSLREKFGVDPADYLISLTSKYILSELGSPGKSGSFFYYSKDYRFIIKTIHYTEHKFMRRILKEYHQHISENPSTLLCRYYGLHRIKLPYGRKIHFVVMSNVFPPNKDIHETYDLKGSTLGRFLPEEEIRKNPYAVMKDLNWEKRERKLKLGPRKRKLFIGQLVRDVTLLSQLNIMDYSLLIGVHDMLRGNKDNVRDTTLQTFQPDTKSVQRRITLMRKRTSKAQVVREAIAEANPDKLDVSKLPEEALERRNCIFYAEDGGFQATDESDQPLPVLYSLGIIDILTPYDIKKKSEHIYKSLTQDKNAISAVRPSQYGQRFLEFMATAVLEHNQDIPHEFKLKSRAKHFFRHD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NMN1</accession>
    <name>A0A1C7NMN1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Paladin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">PALD1_1</name>
        <name evidence="2" type="ORF">A0J61_03428</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000147">
        <property type="protein sequence ID" value="OBZ88524.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="InParanoid" id="A0A1C7NMN1"/>
    <dbReference type="OrthoDB" id="66369at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd14496">
        <property type="entry name" value="PTP_paladin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.190.10">
        <property type="entry name" value="Protein tyrosine phosphatase superfamily"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029021">
        <property type="entry name" value="Prot-tyrosine_phosphatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050561">
        <property type="entry name" value="PTP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23339">
        <property type="entry name" value="TYROSINE SPECIFIC PROTEIN PHOSPHATASE AND DUAL SPECIFICITY PROTEIN PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14566">
        <property type="entry name" value="PTPlike_phytase"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM01301">
        <property type="entry name" value="PTPlike_phytase"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52799">
        <property type="entry name" value="(Phosphotyrosine protein) phosphatases II"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="23"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="23"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="66"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="79"/>
            <end position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ88524.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="1505" mass="170896" checksum="09FBB3015E95F55E" modified="2016-11-30" version="1">MSFLNAYHQLSSSPKSNGNFSLYAESSSTRRGSVNSTSESSPILPRKPFESSIDQPKCFVPPKLISGLNGNSGPSSGNHTRQNSFQSGTDQSFNTHFQKRDQETVLDPYSLLRMAPHIVKSRKGSVLARNTILKMDHFLSGTNTNLDFHLQGAPNFRIAELNVHGVAQPTVIGLSTILSMLNCHPKSASPSSSCTWFSTREEPLVYLNGAPYVLRDYADPMQNMSIFYGINAARLEKLEERLKTDILKEAQSLGGLLLVHQELSDKSVVPCFIAADKVQTPKEVFQEFQSKGYRLKYFRIPISPEQAPEENYFDEYINVIRSLEPTDPLIFNCGIGAVRTTVGIIIAQIIRRTQLIERGQPDPFPVPGYSYSTFTSDNASTPDDANSSRFVKSFEEADATNAKNNALLRVVIILENALSSKKMNRSATEWMLERGSWIENLKEALLGNYQSIMSLTTVLESGIFSKRILDTVIDKSDAVVNLRESILTNRIKQMVQAPSEYNDNTYLRKALDGLQRYFFLLCFTAYVNESPNTKFETRFSSWVRARTEIWAMLQNMRRKGPRPYFFRPIEDLHFINSATTHGQKFANNALSKRTGHHALTQGMFNMTGAGSQPNLDITVEMEEFALNSRTGVVLSSQTILKVDFWHFGYLADSLDESSEEETTLQQQQHVSERHHAFVIDGASNFRRIENTHVYGVAQPTVNGLRQVIRNLLQDRPKNERILWINLREEPIIYINGIPYVLRDRAFTLRNLRAYKGITGSRMEQLEERLKEDVIREVKQSGGRILLHGEDKDGNVLSSWEEVNIEDIMTVREVMEFAGFEVQHELAQRDSSDEEGLQQGKTVSDEESILEYHRVPITAEKAPEWRDFDDLTSLITGVDLSKTAIIMNCQVGLGRSTTGTVIASLLTRWIRPKSNSSRRNSLDSTEAPKSRYPSYQIINSLLRVIRRGLENKGVVDTVIEQCAIHGTHLITVIESARIQAEKEKEDDPSQFKRTVKRGITSLERYFMLICFQAYLDSTSPSLVRDTESFGLWMKRHPELGTILQDLLETKDEFSALVPVEQSLGGGDGIALSSEVMRVVTARHGQVLAQQTILKHDAFPGCQKMSLKEKIPGAYNFRRIEINQAKHAVKEGGLAATVSGLAADMERDDESPLTPPFISGCAMPNKDAIKSILKAMQAGPGGRRWVYWTCLREEPVLYVNKNPYVLRLFIDPLKNLETTGISRERVESMEDRMRLDVIQELDEYDNRMLLHDEDSGFNLLPLWETVPKELVETPRQVFESIRAEGYQVDYLRIPITDEQAPIPDVFDQLIERMHTANQGVDMIFNCQMGRGRTTTGMVVASLLSMILSNDAVNEINDPLTTSFQEENDSSHDERERYQNGEYRVILQLVTVLTYGKLAKRFTDQAINMCDHMQNLRKAIYDYKLRFEAMTDQGSKKWKATREVAINYLVRYFYLIVFANYLLEEMRVSNNTSETAFKEAQKLPTFKEWLKGRREIMNIISLNTLDLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NMR4</accession>
    <name>A0A1C7NMR4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">GTPase-activating protein gyp1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">gyp1_1</name>
        <name evidence="3" type="ORF">A0J61_01577</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000052">
        <property type="protein sequence ID" value="OBZ90375.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="FunCoup" id="A0A1C7NMR4">
        <property type="interactions" value="752"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NMR4"/>
    <dbReference type="InParanoid" id="A0A1C7NMR4"/>
    <dbReference type="OrthoDB" id="26371at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.750:FF:000009">
        <property type="entry name" value="TBC1 domain family member 22A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.270:FF:000037">
        <property type="entry name" value="TBC1 domain family member 22A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.472.80:FF:000001">
        <property type="entry name" value="TBC1 domain family member 22B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.270">
        <property type="entry name" value="putative rabgap domain of human tbc1 domain family member 14 like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.750">
        <property type="entry name" value="Ypt/Rab-GAP domain of gyp1p, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.80">
        <property type="entry name" value="Ypt/Rab-GAP domain of gyp1p, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000195">
        <property type="entry name" value="Rab-GAP-TBC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035969">
        <property type="entry name" value="Rab-GAP_TBC_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22957:SF26">
        <property type="entry name" value="LD44506P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22957">
        <property type="entry name" value="TBC1 DOMAIN FAMILY MEMBER GTPASE-ACTIVATING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00566">
        <property type="entry name" value="RabGAP-TBC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00164">
        <property type="entry name" value="TBC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47923">
        <property type="entry name" value="Ypt/Rab-GAP domain of gyp1p"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50086">
        <property type="entry name" value="TBC_RABGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rab-GAP TBC" evidence="2">
        <location>
            <begin position="236"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="77"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="77"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="91"/>
            <end position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ90375.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="531" mass="60924" checksum="1277A52AD9A2569F" modified="2016-11-30" version="1">MEQRSQKSFWKRKGIKLPGSVAIIPSWPNTPPPINNSNTLQSSPIVGARYTYASLTTTHDDHSKIAMLPSQYMQSTTYPTNTYSSDQTKKTPQHKQQSSKRNKHSRTASHTKSFNAFLMDTNDEWSDNIMESKENKPMDVIEKDPTIDHQALEKASKAAEAVMSPHVVTSKIANQKPKNAKGTKDHIEQLLLDPSHSLKWIVDEESSEPTKIRKFKEILSVTNVDLVALRSLSWSGIPEEVRMMAWQLLLGYLPCNSARRETTLARKRKEYSDSVTAXYARGTAGLDQALWHQIHIDIPRTNPGIPLYQYEATQLCLERILYQWAIRHPASGYVQGINDLVTPIFEVFLSAYIDEDPEQYDVSKLDKEVLSVIEADSFWCLSKLLDGIQDNYTFAQPGIQRQITTLKELVTRIDAHLSQHLQNEGIEFIQFAFRWMNCLLMRELPLRSTVRMWDTYLAEGSSEGFSEFHVYVCAAFLVKWSNQLQKLDFQGVMIFLQQLPTQGWQEKDVELLLSEAYMWKTLFHNAPNHLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NNH2</accession>
    <name>A0A1C7NNH2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="16">Peregrin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="16" type="primary">BRPF1_1</name>
        <name evidence="16" type="ORF">A0J61_01294</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000039">
        <property type="protein sequence ID" value="OBZ90661.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NNH2"/>
    <dbReference type="FunCoup" id="A0A1C7NNH2">
        <property type="interactions" value="44"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NNH2"/>
    <dbReference type="InParanoid" id="A0A1C7NNH2"/>
    <dbReference type="OrthoDB" id="20839at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006325">
        <property type="term" value="P:chromatin organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd04369">
        <property type="entry name" value="Bromodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd15492">
        <property type="entry name" value="PHD_BRPF_JADE_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd05839">
        <property type="entry name" value="PWWP_BRPF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.40.10:FF:000008">
        <property type="entry name" value="Bromodomain containing 1, isoform CRA_a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.40.10:FF:000007">
        <property type="entry name" value="Bromodomain containing 1, isoform CRA_b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.920.10">
        <property type="entry name" value="Bromodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001487">
        <property type="entry name" value="Bromodomain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036427">
        <property type="entry name" value="Bromodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019542">
        <property type="entry name" value="Enhancer_polycomb-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034732">
        <property type="entry name" value="EPHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050701">
        <property type="entry name" value="Histone_Mod_Regulator"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000313">
        <property type="entry name" value="PWWP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019786">
        <property type="entry name" value="Zinc_finger_PHD-type_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001965">
        <property type="entry name" value="Znf_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019787">
        <property type="entry name" value="Znf_PHD-finger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13793:SF107">
        <property type="entry name" value="BROMODOMAIN-CONTAINING PROTEIN HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13793">
        <property type="entry name" value="PHD FINGER PROTEINS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00439">
        <property type="entry name" value="Bromodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10513">
        <property type="entry name" value="EPL1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13831">
        <property type="entry name" value="PHD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00855">
        <property type="entry name" value="PWWP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13832">
        <property type="entry name" value="zf-HC5HC2H_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00503">
        <property type="entry name" value="BROMODOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00297">
        <property type="entry name" value="BROMO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00249">
        <property type="entry name" value="PHD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00293">
        <property type="entry name" value="PWWP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47370">
        <property type="entry name" value="Bromodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63748">
        <property type="entry name" value="Tudor/PWWP/MBT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50014">
        <property type="entry name" value="BROMODOMAIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51805">
        <property type="entry name" value="EPHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50812">
        <property type="entry name" value="PWWP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01359">
        <property type="entry name" value="ZF_PHD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50016">
        <property type="entry name" value="ZF_PHD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6 8" id="KW-0103">Bromodomain</keyword>
    <keyword evidence="10" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 9" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="PHD-type" evidence="13">
        <location>
            <begin position="180"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="domain" description="PHD-type" evidence="15">
        <location>
            <begin position="234"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="domain" description="Bromo" evidence="12">
        <location>
            <begin position="563"/>
            <end position="633"/>
        </location>
    </feature>
    <feature type="domain" description="PWWP" evidence="14">
        <location>
            <begin position="857"/>
            <end position="925"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="677"/>
            <end position="848"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="10">
        <location>
            <begin position="375"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="677"/>
            <end position="688"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="702"/>
            <end position="719"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="733"/>
            <end position="749"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="11">
        <location>
            <begin position="809"/>
            <end position="835"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50812"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51805"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="OBZ90661.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="985" mass="113571" checksum="2392DA7767F2562B" modified="2016-11-30" version="1">MLIGDNKHRRGRPRKQPASPITTEKPREERSFTDFFPDLDIREPLTIVKVSPLSLHTSLTEDNTEDTKKSTGELRKQFKLPQPSFRLVSSHLPGNFERPQQYIHYTEPTESDLFQTVEYDMDEQDDIWLQIYNKERKKENIGEISSELFEAMMDQIEKEWFNLVKNLPKKTAEEPVLPEDSKCAVCDDGECENSNAIVFCDGCNLAVHQDCYGIPYIPEGQWLCRKCMISPENPVSCLFCPNEGGALKQTTTNQWGHLLCAIWIPEVSLSNSVYMEPIDNIESIPKSRWKLQCYICKRRQGACIQCDNKHCFVAFHVTCARWARLCMRMKLHGTHYDGVLLKAYCDRHTPRDYYHSTHLEQAQRWFLKHKQAMPRKRYVDEEDEAEEIKEDLKKLMKKKKKKKNNNAQVLPASYKAARAHQHHYNTTTGTPIAPEYILNTLEKLPCVQKETKIKKKAAMVAAVCRYWSLKREARRGAPLLKRLHLEPWTASASQLKQSEVEKAQKASTLMTLRGDLEKVRMLSEQVQKRERQKLERIRKQKAYLEMIFYPIQCILQTVLDQLIELDKKELFRYPVTKEIAPDYHDIIKQPMSFSDIIKKLNDHSYLSLDEFEHDLNLIWRNSMTYNKSDTAYFKLAQKLEKVMQELMSHARHSYEQLNPVFGLLDVEIDPDIFSYGSTTHIPPSLTNNSSSSSSSDEAPEEQGEKQQQPKEQEQQEQKNDINSNEEGEESKVTTSDSTLSSSSPLSLTPPEKRKVDTDDSLPQKRSRLSSPEPPKKRMTRSATEGQKRSLRPRILKEESTPLPLLTQSTPPPSSPPPSTPSPPTPPPPSTPPPTLIRPSMPKRRSTRPKKLTVHFANGEIVWAHVRGFPPHPAEIVNPQTTKREIPDRVLKLQPSFPDRVLVAFFLVSEAHTWGWMEKSEISVFGQFEIDTHMLLKAKRTRKSHRIQEVKHGYQHACNLLGLDPDVALTAVFPHPTSQPNQHNKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NP33</accession>
    <name>A0A1C7NP33_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">A0J61_02932</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000118">
        <property type="protein sequence ID" value="OBZ89024.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NP33"/>
    <dbReference type="STRING" id="101091.A0A1C7NP33"/>
    <dbReference type="InParanoid" id="A0A1C7NP33"/>
    <dbReference type="OrthoDB" id="2333384at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030674">
        <property type="term" value="F:protein-macromolecule adaptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031625">
        <property type="term" value="F:ubiquitin protein ligase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070086">
        <property type="term" value="P:ubiquitin-dependent endocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.640">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014752">
        <property type="entry name" value="Arrestin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011021">
        <property type="entry name" value="Arrestin-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011022">
        <property type="entry name" value="Arrestin_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050357">
        <property type="entry name" value="Arrestin_domain-protein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11188">
        <property type="entry name" value="ARRESTIN DOMAIN CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11188:SF17">
        <property type="entry name" value="FI21816P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02752">
        <property type="entry name" value="Arrestin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00339">
        <property type="entry name" value="Arrestin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="E set domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Arrestin-like N-terminal" evidence="2">
        <location>
            <begin position="37"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="domain" description="Arrestin C-terminal-like" evidence="3">
        <location>
            <begin position="189"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="346"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="460"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="502"/>
            <end position="543"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="666"/>
            <end position="696"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="381"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="525"/>
            <end position="535"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="666"/>
            <end position="680"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="681"/>
            <end position="696"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02752"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OBZ89024.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="696" mass="78199" checksum="38995F6639B02556" modified="2016-11-30" version="1">MKDGILSVEVESFKKHLNFLGPEKTPIKDMADNDHSQLLKGHIRLTLAKATKVKSVSVKFKGESAVNHSLKAPNNHFHTYQHQQQYHPQQDLLTPILPKLKSKVLLKPVMLDAGVHLIPWEIEIPDIYPRSFSTRGGFIRYRIEAKMTVGCSKVVIASQPIVIHRHLLSSRDTALHIASRIYEHIVQKKFLFELELPKIVYIDQGYIPINIMFKCIDKSPVKFISTQLIQIEIYKCRNVSKAEIDMAFMCSKKSSTSVSMKAHKPAKHNDMGLSRFFRQTRPVMLNTIDQNDKFDSIPLILQHQLDTNLLCGIESPIITIAHQIELTFNFGQNREEVRVKMPIRLSTTPHVFPPPDDPSLRHSFERRPHKRPLAVEVSDSPTRRSDSLHARPDKQHSRREGSGATSQAEQGIRKLKSAQCLLRGRSGSLPAQTQESKELPSLPPLSLPLIYAVNKASSFHEEDIQPTPISKKKSNKSLDEKHHPLTSAATFPTTSTIHSFKPSYNTFSGLPPPPRRTRTKKESPTDSYSSDSPTDLPVPTRSASASNIFARDSSAEPPLLSPFLSKPNLARPSLNISKSTKVPALSSPPLLTNKRASAAYTQNLTKDPAHTTSNDAPDHIAFAYMVASHYLDSSLPSHPSLTKRVSSMAIHPTSNIDNRMTKIYYEEDSDEDEDDDEDDIVVDKTENERESHVITC</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NP34</accession>
    <name>A0A1C7NP34_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Cysteine and glycine-rich protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">CSRP1</name>
        <name evidence="10" type="ORF">A0J61_01176</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000034">
        <property type="protein sequence ID" value="OBZ90768.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NP34"/>
    <dbReference type="STRING" id="101091.A0A1C7NP34"/>
    <dbReference type="InParanoid" id="A0A1C7NP34"/>
    <dbReference type="OrthoDB" id="8062037at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042805">
        <property type="term" value="F:actinin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008307">
        <property type="term" value="F:structural constituent of muscle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030036">
        <property type="term" value="P:actin cytoskeleton organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd09326">
        <property type="entry name" value="LIM_CRP_like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="2.10.110.10:FF:000001">
        <property type="entry name" value="Cysteine and glycine-rich protein 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.110.10">
        <property type="entry name" value="Cysteine Rich Protein"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001781">
        <property type="entry name" value="Znf_LIM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24215:SF35">
        <property type="entry name" value="MUSCLE LIM PROTEIN MLP84B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24215">
        <property type="entry name" value="RHO-GTPASE-ACTIVATING PROTEIN LRG1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00412">
        <property type="entry name" value="LIM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00132">
        <property type="entry name" value="LIM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57716">
        <property type="entry name" value="Glucocorticoid receptor-like (DNA-binding domain)"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00478">
        <property type="entry name" value="LIM_DOMAIN_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50023">
        <property type="entry name" value="LIM_DOMAIN_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0440">LIM domain</keyword>
    <keyword evidence="2 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 7" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="LIM zinc-binding" evidence="9">
        <location>
            <begin position="9"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="domain" description="LIM zinc-binding" evidence="9">
        <location>
            <begin position="173"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="94"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="8">
        <location>
            <begin position="113"/>
            <end position="151"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023038"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OBZ90768.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="249" mass="27623" checksum="FCBFCF8F6AE74AF7" modified="2016-11-30" version="1">MPPRFGGAPQCPRCQKSVYMAEQVIGPGGFWHKSCLTCKECNKRLDSTTLTEKDDEAYCKTCYSRQWGPKGYGFAGGAAFLSTENKLPSEIIKERINDGSITTMDQPTSREIPPTPPRPVAPPTPPRPVEPVTSRPPVPPKPDLRPAPPEKPTSLSNRTSYVPKKFNFTSQQDICTRCGKAVYAAELMYGAGNKYHKMCLKCTDCGKRLDSTNMVDRDFELYCRGCYSKSFGPKGFGYNNLLMPEGATR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NP94</accession>
    <name>A0A1C7NP94_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Dipeptidyl-peptidase V</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">A0J61_01031</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S9C family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000029">
        <property type="protein sequence ID" value="OBZ90917.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NP94"/>
    <dbReference type="FunCoup" id="A0A1C7NP94">
        <property type="interactions" value="26"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NP94"/>
    <dbReference type="InParanoid" id="A0A1C7NP94"/>
    <dbReference type="OrthoDB" id="416344at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1820:FF:000028">
        <property type="entry name" value="S9 family peptidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.30">
        <property type="entry name" value="TolB, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011042">
        <property type="entry name" value="6-blade_b-propeller_TolB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001375">
        <property type="entry name" value="Peptidase_S9_cat"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42776:SF13">
        <property type="entry name" value="DIPEPTIDYL-PEPTIDASE 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42776">
        <property type="entry name" value="SERINE PEPTIDASE S9 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00326">
        <property type="entry name" value="Peptidase_S9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82171">
        <property type="entry name" value="DPP6 N-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008889813" description="Dipeptidyl-peptidase V" evidence="6">
        <location>
            <begin position="23"/>
            <end position="692"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S9 prolyl oligopeptidase catalytic" evidence="7">
        <location>
            <begin position="486"/>
            <end position="685"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00032829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OBZ90917.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="692" mass="77575" checksum="9B39F817DF52FBCD" modified="2016-11-30" version="1">MLIKSKLLFFGASLFNIAVVMAEKFTPADLVQLPRPGVPVTSPSGALAVYAQSAYNITEAKTTRNLFLLDIERNSVEELTKASFDTSDNDPFFLDDDHIAFIHHDEELKEDVDQLYVIDLNNRNNGPYRLSDFPISIGDVKYNANEKLLAFSAAVYPEDGTLEGTLKKDKEIKETKKDTALAYDELMVRHWDRYVPEKKNSIFVVHLSIDNKKYKIESEPINLLKDTGLESPLFPQGGADDYAISPDASQVAFLAKINTKDNAWQTSAHIYTVSTSGKESPKAINKDIPAASSCPHFTSSGLLVYFQMMVPQYESDRNRITTYNLKTKERKVIAESWDSSPHEIASSINGDILYVTAEQQGRNKVFAIDLETESVKTLTNEKYATGLSVLPSGNLFFGASSMKHPVRPHLLNIASTEIKPLAVESGLKQKLDKIDFSNPEDVRFTGALNQEVHGWFLKPVGFEEGKKYPVAFLIHGGPQGAWNDNWSTRWNPQIFAGAGYAVVAINPHGSTGYGQAFTDSICHNWGSYPFQDLEIGLDYVLSKYNYLDPKRVAGLGASYGGYMTNWINGNSNKFKVLVNHDGVFSAAQVYYTTDELYFSEREFGGSPIYPENRAGFEKWSPSNYVQNWKTPMLVIHGGNDFRLTLGESLSTFTALQRQGVPSRLLYFPDESHWVLKPANSLRWHKEGKLKQY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NQA1</accession>
    <name>A0A1C7NQA1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">60S ribosomal protein L38-1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">rpl38a_0</name>
        <name evidence="5" type="ORF">A0J61_00687</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the eukaryotic ribosomal protein eL38 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000016">
        <property type="protein sequence ID" value="OBZ91292.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NQA1"/>
    <dbReference type="FunCoup" id="A0A1C7NQA1">
        <property type="interactions" value="570"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NQA1"/>
    <dbReference type="InParanoid" id="A0A1C7NQA1"/>
    <dbReference type="OrthoDB" id="10250488at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022625">
        <property type="term" value="C:cytosolic large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022618">
        <property type="term" value="P:protein-RNA complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.720.90:FF:000001">
        <property type="entry name" value="60S ribosomal protein L38"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.720.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002675">
        <property type="entry name" value="Ribosomal_eL38"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038464">
        <property type="entry name" value="Ribosomal_eL38_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10965">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L38"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10965:SF0">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN EL38"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01781">
        <property type="entry name" value="Ribosomal_L38e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 5" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003445"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OBZ91292.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="69" mass="7944" checksum="DF5963F53E342F42" modified="2016-11-30" version="1">MPQQIKDIKQFLEIARRKDAQSARIKKNADSVKFKVRCSRYLYTLVVKDKSKAAKLKQSLPPALVVNEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NQN2</accession>
    <name>A0A1C7NQN2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Ribosomal lysine N-methyltransferase set10</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">set10</name>
        <name evidence="5" type="ORF">A0J61_00727</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000018">
        <property type="protein sequence ID" value="OBZ91219.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NQN2"/>
    <dbReference type="FunCoup" id="A0A1C7NQN2">
        <property type="interactions" value="413"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NQN2"/>
    <dbReference type="InParanoid" id="A0A1C7NQN2"/>
    <dbReference type="OrthoDB" id="42889at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016279">
        <property type="term" value="F:protein-lysine N-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd19180">
        <property type="entry name" value="SET_SpSET10-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1420.10">
        <property type="entry name" value="Rubisco LSMT, substrate-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1410.10">
        <property type="entry name" value="set domain protein methyltransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015353">
        <property type="entry name" value="Rubisco_LSMT_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036464">
        <property type="entry name" value="Rubisco_LSMT_subst-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044432">
        <property type="entry name" value="Set10/Efm1_SET"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001214">
        <property type="entry name" value="SET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046341">
        <property type="entry name" value="SET_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050600">
        <property type="entry name" value="SETD3_SETD6_MTase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13271:SF147">
        <property type="entry name" value="PROTEIN-LYSINE N-METHYLTRANSFERASE EFM1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13271">
        <property type="entry name" value="UNCHARACTERIZED PUTATIVE METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09273">
        <property type="entry name" value="Rubis-subs-bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00856">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81822">
        <property type="entry name" value="RuBisCo LSMT C-terminal, substrate-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82199">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50280">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 5" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2 5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="SET" evidence="4">
        <location>
            <begin position="16"/>
            <end position="231"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OBZ91219.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="567" mass="64788" checksum="16EF747D562FF7B8" modified="2016-11-30" version="1">MNVYTSWILDNGGRMNKIEIRNDSEDANNGVYATDRVEDGENFFTIPFKICISERIARQALPFCSKYSGHAVSALFLVLEKAKGETSFYWPYINILPKSIKTAMSFDESDLTFVKNTNLESVVRERKANLYAEYEGLLNDLPETLDKESISWEDFLWSFSVFSSRAFPYTLIDPHTEDQSAQVLCPLADALNHKPNTKITWSREGDMDNGSLTFIAGEAHNAGDQIFNNYGPKSNEELLLGYGFCFEHNEHDFVALKTNFSQDPNGQLKLDILNQCHVSSGNTDPFTFYIHRHTIPDVFLKMMRVLVMNSMETKFYSKCTEGSLLDFVGYRNEIMALNVTISLLQGRLSALKTVVFKEESSLTSWQKYALMYRKGQEDIYEATVKKIEEMKRLLIQRMKQDQKEKSLAPVAPFIAILNPSHCFSSIDIDSDDSFYTLDQVVITVQSILKKNPALEQVVKDNFDDIEAEKDIIMMLGLIGENSKPNSQYREFFDKATERAVVDKHLEEIEDDVLEELQEMYESMVPAFVEAYPSVFDPVLYSLEAFVWADYVISNYSLSGNLFAIVPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NR46</accession>
    <name>A0A1C7NR46_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 6">Queuosine 5'-phosphate N-glycosylase/hydrolase</fullName>
            <ecNumber evidence="6">3.2.2.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4 6">Queuosine-nucleotide N-glycosylase/hydrolase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">A0J61_00504</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Catalyzes the hydrolysis of queuosine 5'-phosphate, releasing the nucleobase queuine (q). Is required for salvage of queuine from exogenous queuosine (Q) that is imported and then converted to queuosine 5'-phosphate intracellularly.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5 6">
            <text>queuosine 5'-phosphate + H2O = queuine + D-ribose 5-phosphate</text>
            <dbReference type="Rhea" id="RHEA:75387"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:17433"/>
            <dbReference type="ChEBI" id="CHEBI:78346"/>
            <dbReference type="ChEBI" id="CHEBI:194371"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="5 6">
            <dbReference type="Rhea" id="RHEA:75388"/>
        </physiologicalReaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the QNG1 protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.2.-" evidence="6"/>
    <dbReference type="EMBL" id="LUGH01000011">
        <property type="protein sequence ID" value="OBZ91440.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NR46"/>
    <dbReference type="FunCoup" id="A0A1C7NR46">
        <property type="interactions" value="232"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NR46"/>
    <dbReference type="InParanoid" id="A0A1C7NR46"/>
    <dbReference type="OrthoDB" id="416777at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006400">
        <property type="term" value="P:tRNA modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019438">
        <property type="entry name" value="Q_salvage"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21314:SF0">
        <property type="entry name" value="QUEUOSINE 5'-PHOSPHATE N-GLYCOSYLASE_HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21314">
        <property type="entry name" value="QUEUOSINE 5'-PHOSPHATE N-GLYCOSYLASE_HYDROLASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10343">
        <property type="entry name" value="Q_salvage"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00035119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00035306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00035393"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00048204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU365002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OBZ91440.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="346" mass="40064" checksum="03244B76F9CBBCB2" modified="2016-11-30" version="1">MFSMPLTENKVLDSAKFIAEHSSHVTIPKENLDDAAQTILHNMKIRKYSTATWNEHPMHPKTADCHTVDWIFLIDLLNFSFWSDLDVSDKKTPHPDRYAIIYDNQSYTGYWSLCAAINRALDRQIPITNPAYYGAKASDDELAEIFKSDTKEQAPMLTERIRVMREAGKVLCEKFDGSFVNCIAQANHSAQKLLDIIVTNFTSFQDIHEFHGKKVYILKRAQILIADLWACFDGQDYGQFNDIDSITMFADYRVPQALYQLGLLRYSSELIKKLEKRIYFPSGCNDEVEIRGNSIWAVELVRQRIQQLEPTIKINAILIDFYIWDMAKEIQDQMTVPTHCTRSCFY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NR79</accession>
    <name>A0A1C7NR79_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_00437</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000010">
        <property type="protein sequence ID" value="OBZ91470.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NR79"/>
    <dbReference type="InParanoid" id="A0A1C7NR79"/>
    <dbReference type="OrthoDB" id="203796at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37848">
        <property type="entry name" value="EXPRESSED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37848:SF1">
        <property type="entry name" value="SUN DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="301"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="15"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="68"/>
            <end position="94"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ91470.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="378" mass="43041" checksum="306D64FC08519C40" modified="2016-11-30" version="1">MSKSQSNYYYAYSSPPLQNNSGSASDQQDVTKNSGPPPSYDEALQPPLSSPTSNSHQNALDGYVLDNTAPTQLPGTPSNTSDYGSATPNSNQDTVPLLSNHDDDLSFQGRPLPPGYSVHNAAYKTTTDGVVSRDKHINEDGEALVRFLYQHNTPPRLIIHFHGYHEETTWTVETVRNRDGDEVQQRVPTTRQIDDFKFDLDCSADVSSECQGIYLLPDPKTGEQKRLRQLCDEYVHSKNALKELKMTKEIEWDFNNLTRALTTAIRDSGFYDFINITYSLENHETVVKTDEKISKLADNKYIRFFFFITCLWILAWPIIYFCKEKFGHSTLKSAWKMNVSEREWYGLHVGEITRKCRGPDCFSNGRIHPNGFPVNMRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NRG3</accession>
    <name>A0A1C7NRG3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_00250</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000005">
        <property type="protein sequence ID" value="OBZ91702.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NRG3"/>
    <dbReference type="InParanoid" id="A0A1C7NRG3"/>
    <dbReference type="OrthoDB" id="5985073at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd22785">
        <property type="entry name" value="DPBB_MltA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008889843" evidence="1">
        <location>
            <begin position="19"/>
            <end position="243"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ91702.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="243" mass="27161" checksum="3367739A40896EC4" modified="2016-11-30" version="1">MKFSVCSTLFALIAVVSAQVAPSSGKNEVIRQRDDRVKRSLETKRSLKSCYSKATLTMYWIPKEGDKDMLNNGKTVTLSGSKNKKLKTTSGSTIAKVSKTTYEKFQMEGTGLLKNGVMVNLDSGNDTFMKVNRKKSPYGLGSEENNRLVPWISVASNDLRKGTKLYIKQLDGLKLPDGKKHNGCVRVDDEGWSFSGCQLDFFVLQFSAYKKLDDMIPNKVTVQQKDCKILDYVTSSVKKWAVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NRI5</accession>
    <name>A0A1C7NRI5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Alpha-1,2 mannosyltransferase KTR1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">KTR1_0</name>
        <name evidence="6" type="ORF">A0J61_00350</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the glycosyltransferase 15 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000007">
        <property type="protein sequence ID" value="OBZ91628.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NRI5"/>
    <dbReference type="FunCoup" id="A0A1C7NRI5">
        <property type="interactions" value="158"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NRI5"/>
    <dbReference type="InParanoid" id="A0A1C7NRI5"/>
    <dbReference type="OrthoDB" id="439943at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000026">
        <property type="term" value="F:alpha-1,2-mannosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000032">
        <property type="term" value="P:cell wall mannoprotein biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006487">
        <property type="term" value="P:protein N-linked glycosylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.550.10:FF:000051">
        <property type="entry name" value="Alpha-1,2-mannosyltransferase (Ktr4)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="entry name" value="Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002685">
        <property type="entry name" value="Glyco_trans_15"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31121">
        <property type="entry name" value="ALPHA-1,2 MANNOSYLTRANSFERASE KTR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31121:SF6">
        <property type="entry name" value="ALPHA-1,2 MANNOSYLTRANSFERASE KTR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01793">
        <property type="entry name" value="Glyco_transf_15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF018153">
        <property type="entry name" value="Glyco_trans_15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0808">Transferase</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="7"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="60"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="69"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="3">
        <location>
            <position position="359"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR018153-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OBZ91628.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="474" mass="55963" checksum="61A747522E4BD279" modified="2016-11-30" version="1">MCLSRTAFRIVIATVIILGAILIYRSSTSENKYCNNSTECYNLLKEKAQLLKETTANSLAGFAQQEPSNEQKERQEKEQDKAYKAMLQTPEDKETDLKPEEEIKNKVKELEKEGRNKEGITSAVDDKKTRLEKEYQALTDTTLPRVKAAFVVLVRNRELYALRSSMRYLEDRFNHKYEYPWIFLNEEEFTDEFIEMTQSMTKAKVHYGLVPKEHWSYPDWIDQEHAKQCRQSMVDQNIIYGGSESYRHMCRYQSGFFMMHPLLDDLDYYWRVEPGVKFSCDIDYDPFRLMQERDLKYGFTIALREYKATIPTLWNATIDFAKKYPQYIYPRTRPDSLLNFISDDNGWSYNMCHFWSNFEIASLKYMRSEGYQAYFRHLDEAGGFFYERWGDAPVHSIAVAMMLKQSDVHWFYDIGYKHDNFEHCPTEEPWLVQSKCYCDPVTSFDSNAGSCTNLYLKTVNSTASNFIVTRQDKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NRL1</accession>
    <name>A0A1C7NRL1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_00392</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000008">
        <property type="protein sequence ID" value="OBZ91579.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NRL1"/>
    <dbReference type="STRING" id="101091.A0A1C7NRL1"/>
    <dbReference type="InParanoid" id="A0A1C7NRL1"/>
    <dbReference type="OrthoDB" id="10267139at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043743">
        <property type="term" value="F:LPPG:FO 2-phospho-L-lactate transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10680">
        <property type="entry name" value="CofD-like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002882">
        <property type="entry name" value="CofD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038136">
        <property type="entry name" value="CofD-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31240">
        <property type="entry name" value="MATERNAL EFFECT EMBRYO ARREST 18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31240:SF0">
        <property type="entry name" value="MATERNAL EFFECT EMBRYO ARREST 18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01933">
        <property type="entry name" value="CofD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF142338">
        <property type="entry name" value="CofD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="390"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="390"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="403"/>
            <end position="418"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ91579.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="510" mass="56604" checksum="4A88E1423BBFB09B" modified="2016-11-30" version="1">MEASASSFVIFSGGSACNHILDSFQKTGANEVSYILGISDNGGSTSELLRVLGGPSVGDLRSRLIRLMDILTENTSKEMKAIKTLLSYRLPVDKRNHQRVRDEWALIVEGRHRYLWNDISVEKREAIRGFLTLFDFEILKRAHKRFNFCNGSIGNFFLTGARLFTGSLEAAIFLFASIIGISCVPTSVVPVINTNQTATIAACLMNGETLVGQCEISHPSPCQQKKNRKQGILTPARKRINPIDAFCYFEDPINLKATEEEDENINLFFSKQVDEKLNSPIDRIYYINEFGQEIYPVPNPKVIGHLSSKKTLVYSIGSLYTSLIPCLVLRGVGNAIVQSHSLKYKILLLNGTNDRETSDYTALDFINAITNALNESQRIDARRAFYESCDDDDDQEEIPDYVSSRTSSISSTTPHTPPSYMSHLSNVGSIPASPSQRYPPFPHNAFYPSSASSFITHMIYLDNSAIPVDVEAIERLGIQCVCIQGATSATGEPIYSQTSFAHVIESIVYS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NRZ1</accession>
    <name>A0A1C7NRZ1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_00166</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000003">
        <property type="protein sequence ID" value="OBZ91788.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NRZ1"/>
    <dbReference type="InParanoid" id="A0A1C7NRZ1"/>
    <dbReference type="OrthoDB" id="2408655at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="206"/>
            <end position="242"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ91788.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="242" mass="27878" checksum="3E0E2368BAD9706F" modified="2016-11-30" version="1">MNHTPIVRHHPYAYCDGKSNSIEQKLSQYTRPELQQLQQKNVQLLSNDSMVNTLPDKGAKLKEINAIIDRLLLDSRTISASDDITVENTDTLDCPLTKKLDEMTVLTSHQGARKRSVDLANQQANHHHPVNSLLVKRSHHQRPSLSIFQHYIQPQQSNDSQDKTHNAKVRMLSLDESMTLQQQQQFSVQQSERSLDYRRPSKQLLNSLNLPADVIEDEDSDQYEFQSKTDEEEEEGKHMIID</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NS12</accession>
    <name>A0A1C7NS12_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">PH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_00002</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000001">
        <property type="protein sequence ID" value="OBZ91925.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NS12"/>
    <dbReference type="STRING" id="101091.A0A1C7NS12"/>
    <dbReference type="InParanoid" id="A0A1C7NS12"/>
    <dbReference type="OrthoDB" id="5865767at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.50">
        <property type="entry name" value="Transcription Factor, Ets-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041681">
        <property type="entry name" value="PH_9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001849">
        <property type="entry name" value="PH_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013761">
        <property type="entry name" value="SAM/pointed_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37283">
        <property type="entry name" value="PH DOMAIN-CONTAINING PROTEIN YHR131C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37283:SF1">
        <property type="entry name" value="PH DOMAIN-CONTAINING PROTEIN YHR131C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15410">
        <property type="entry name" value="PH_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00233">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47769">
        <property type="entry name" value="SAM/Pointed domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50003">
        <property type="entry name" value="PH_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PH" evidence="2">
        <location>
            <begin position="249"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="152"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="160"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="184"/>
            <end position="193"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ91925.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="427" mass="49281" checksum="486E33C7A0A35BF3" modified="2016-11-30" version="1">MEIQHRHYFNHERINKEAPFLMDKTKLSSIVLGQLSLEQYIPLFQQANIDFDQFVAMSEKDFVSLGLRNEADLDLLSNCARALKTHITKQATDDRILEESNNGPDETNSVMSDYTRCGNINQSDDSMTLVGSVSSESIMRAIHAYDSYHSSRQHEPLVTPSIQGNTSSGSLVAPPGTVIRRSKPGSSSNNNHASRPLSMPVQLPSHLHSLSPPPDYTSTIFGRRLDRCRSMIIPREEEGREELPGYSCTVFKMGYVYVKNELDAPNMRSKWRAWRKLYIELWGTVLRVYRAKPAKSQIDIKNYYRWPLKTPYYYYHKYYYTPIFTISLAGAEASRALDYFRRPNVLRLMTQQGPQFLMKLSSHVEMISWVEHLQAAINISLDLEHRPMPKFMSIPTRALISAPSDPRSIELERIREQRRRDQRETLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NS52</accession>
    <name>A0A1C7NS52_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Histone H1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">H1_0</name>
        <name evidence="9" type="ORF">A0J61_00001</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Chromosome</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1 7">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the histone H1/H5 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000001">
        <property type="protein sequence ID" value="OBZ91927.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NS52"/>
    <dbReference type="STRING" id="101091.A0A1C7NS52"/>
    <dbReference type="InParanoid" id="A0A1C7NS52"/>
    <dbReference type="OrthoDB" id="1110759at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000786">
        <property type="term" value="C:nucleosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003690">
        <property type="term" value="F:double-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031492">
        <property type="term" value="F:nucleosomal DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030527">
        <property type="term" value="F:structural constituent of chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030261">
        <property type="term" value="P:chromosome condensation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045910">
        <property type="term" value="P:negative regulation of DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006334">
        <property type="term" value="P:nucleosome assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00073">
        <property type="entry name" value="H15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005819">
        <property type="entry name" value="H1/H5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005818">
        <property type="entry name" value="Histone_H1/H5_H15"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11467:SF36">
        <property type="entry name" value="HISTONE 24-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11467">
        <property type="entry name" value="HISTONE H1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00538">
        <property type="entry name" value="Linker_histone"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00624">
        <property type="entry name" value="HISTONEH5"/>
    </dbReference>
    <dbReference type="SMART" id="SM00526">
        <property type="entry name" value="H15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51504">
        <property type="entry name" value="H15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0158">Chromosome</keyword>
    <keyword evidence="5 7" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6 7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="H15" evidence="8">
        <location>
            <begin position="18"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00020833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003894"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51504"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OBZ91927.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="81" mass="8660" checksum="900C92E61E0062BD" modified="2016-11-30" version="1" fragment="single">MTAATATSKKAASTKKADHPTYEAMITDAIAALKERKGSSRPAIKKYILANYKVSPGSHFDSQIAAAIKRGHAKDVFSLPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NSD5</accession>
    <name>A0A1C7NSD5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_00543</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000012">
        <property type="protein sequence ID" value="OBZ91406.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NSD5"/>
    <dbReference type="InParanoid" id="A0A1C7NSD5"/>
    <dbReference type="OrthoDB" id="2267458at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ91406.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="156" mass="18221" checksum="9A21260B0149B212" modified="2016-11-30" version="1">MEVKSHTSVLYPIFHDNYHSGTKSQKEIDIDTSIYQLLSLYLNKEEESSLVKMKKSSHTKSYHWKKTGRLLKSQKSWLGEERQKSEQELILERNTLQNSSIQNCGDETLRTKKPRSKSVSFDDKVTVIVSQEKIISKSLDMETQEEEFVDALEYLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NSF5</accession>
    <name>A0A1C7NSF5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Fungal lipase-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">A0J61_00450</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000010">
        <property type="protein sequence ID" value="OBZ91486.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NSF5"/>
    <dbReference type="STRING" id="101091.A0A1C7NSF5"/>
    <dbReference type="InParanoid" id="A0A1C7NSF5"/>
    <dbReference type="OrthoDB" id="426718at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00519">
        <property type="entry name" value="Lipase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002921">
        <property type="entry name" value="Fungal_lipase-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051218">
        <property type="entry name" value="Sec_MonoDiacylglyc_Lipase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45856">
        <property type="entry name" value="ALPHA/BETA-HYDROLASES SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45856:SF24">
        <property type="entry name" value="FUNGAL LIPASE-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01764">
        <property type="entry name" value="Lipase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="101"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="128"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="domain" description="Fungal lipase-type" evidence="4">
        <location>
            <begin position="327"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="256"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="12"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="27"/>
            <end position="36"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01764"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OBZ91486.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="618" mass="70995" checksum="98FC24FCDDB32034" modified="2016-11-30" version="1">MGHDEVDKQQDKNVASNDTTNKQDNIFDGDDDDDDDKSLTETHFSRQHMDEILGVQKHNQKTHGKKAEPELPQPQNIVEWIILWVYRLQRTTTKQYRPSGYWRYAIGVYQNLFLMFYFNWITIFTSPLSAFAFIFTYPIIAVALFMFEIGLKVFMDGLGGNGLVNCISKDFGYGFSIINWGAPQLLLSKKSRLLVRNTLPALGKTASESNSIETEDDQRHRTFDVSIAQTMTILGSLVYERQDKNIVEAYRMLSDFNKNKKNIKEADKQYQQIERDMTRLVWESERVIRKIARSYGLHFAGVTDLKSLGDTFCGLFWPIRHENPFIIVAFKGTTPTNYSEFLVDATLQRTDARSYLFGSAHEGFYSSLFSSHFDVDTRDPYYAIQSAIRERAAQLQKDSKDPSRPVQVWVAGHSLGAAIGSLLFARWLKCPEDIAPMCELRDAYVIGTPAVGDNDFASMFSSFSNLPLSRASTLWRVINKSDIICRIPPGYNSMTIGHYVSSTDFFNYSHIGHAVQITYPMLHEKPLKIYPSSYQSNLTVDIATSSDHFIPEEPPLANRTQEVDVQSYPWWFRPILKGSRNPISLLESFYPFFLRDHIPIHYFEGLERAQVYYSQQND</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NV73</accession>
    <name>A0A1C7NV73_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Cyclin CCL1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">CCL1</name>
        <name evidence="5" type="ORF">A0J61_00561</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the cyclin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000013">
        <property type="protein sequence ID" value="OBZ91374.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NV73"/>
    <dbReference type="FunCoup" id="A0A1C7NV73">
        <property type="interactions" value="705"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NV73"/>
    <dbReference type="InParanoid" id="A0A1C7NV73"/>
    <dbReference type="OrthoDB" id="340962at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070985">
        <property type="term" value="C:transcription factor TFIIK complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061575">
        <property type="term" value="F:cyclin-dependent protein serine/threonine kinase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd20524">
        <property type="entry name" value="CYCLIN_CCNH_rpt1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd20525">
        <property type="entry name" value="CYCLIN_CCNH_rpt2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.10">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013763">
        <property type="entry name" value="Cyclin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036915">
        <property type="entry name" value="Cyclin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043198">
        <property type="entry name" value="Cyclin/Ssn8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031658">
        <property type="entry name" value="Cyclin_C_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006671">
        <property type="entry name" value="Cyclin_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10026">
        <property type="entry name" value="CYCLIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16899">
        <property type="entry name" value="Cyclin_C_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00134">
        <property type="entry name" value="Cyclin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00385">
        <property type="entry name" value="CYCLIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47954">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1 2" id="KW-0195">Cyclin</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cyclin-like" evidence="4">
        <location>
            <begin position="79"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="32"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU000383"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00385"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OBZ91374.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="300" mass="35104" checksum="E2979417020BF17F" modified="2016-11-30" version="1">MTEQQKKPSIFEESTQYQHWRFSPEKIWDIRNKSTEAAISRVRRNLQEEINEHTNTTEHIERDYLSAKEEHALCSFYEIQLQAMSKHCHFSNLVMATAVIYMKRFYLHNTVMDYHPKDVFLTCLFLATKSESERISIDDFGKTLRLPNTANVLKLEFTLSQGLKFQYYVHHPYRPAYGFFLDMQTAPAMDMKALKETYKRVDKAIADILLTDLPLIYQPSQLALAAFMIAGKDNQFDQQIKQYIQHRFSEQEATTLLDVLEGILAYYRAVPAKVTQEEARKIDYKLKLCMNPAMNPDSAM</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MI10</accession>
    <name>A0A1C7MI10_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_11869</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01002618">
        <property type="protein sequence ID" value="OBZ76006.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MI10"/>
    <dbReference type="InParanoid" id="A0A1C7MI10"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="63"/>
            <end position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ76006.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="92" mass="10312" checksum="D5C39B34C9F62C9F" modified="2016-11-30" version="1">MFISQSSKSKRDQESKSSKGKQPFEGVRAAVFEENVPHYLSTVTLDDDKLDPDLATIISNSAFVQQGDKRPLDNAEYQGSNKMSRTENTSRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MTQ1</accession>
    <name>A0A1C7MTQ1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_11729</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01002398">
        <property type="protein sequence ID" value="OBZ80222.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MTQ1"/>
    <dbReference type="InParanoid" id="A0A1C7MTQ1"/>
    <dbReference type="OrthoDB" id="2287166at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="153"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ80222.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="153" mass="16759" checksum="B90649501BD652B7" modified="2016-11-30" version="1" fragment="single">MTTQGDIPWATVAAIGNQMRIRYSPRSRVQETRVKYIPETLFTSPDFESEIINRRAASLVQQALTDGSVLFSFQVGMFKTHIAAYKAIRENIGPVTGFQHLSGYPSNPGKGGTLIEARFVSVDDRRRAMEQGITIGARNFVGTPTSGGAHAKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MTT4</accession>
    <name>A0A1C7MTT4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_11708</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01002371">
        <property type="protein sequence ID" value="OBZ80243.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MTT4"/>
    <dbReference type="InParanoid" id="A0A1C7MTT4"/>
    <dbReference type="OrthoDB" id="2350305at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ80243.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="104" mass="11886" checksum="CA836FB6D845FF60" modified="2016-11-30" version="1">MSNIRVRLTVDQKIKIFDENLKGKLDQVEHGGWAMEKFALSKPLVQQTILKIFSSADELHSNISLKTSRKSAKGSKYPQLDAEVEKYVEDMNNLNQHINKESVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MUQ1</accession>
    <name>A0A1C7MUQ1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">ATP-dependent DNA helicase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_11751</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01002428">
        <property type="protein sequence ID" value="OBZ80199.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MUQ1"/>
    <dbReference type="InParanoid" id="A0A1C7MUQ1"/>
    <dbReference type="OrthoDB" id="2288958at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ80199.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="89" mass="10255" checksum="48C2CC5A827FE0B8" modified="2016-11-30" version="1">MEKSTEELATAQIDRYTRPNRLTSAEFYSLLSKLNMLQRAFRNHVVDHIRHNKNWLDDPKRLKLFVTGGSGTGKKYVNQNTLSSSSQTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MV29</accession>
    <name>A0A1C7MV29_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Integrase catalytic domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_11665</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01002315">
        <property type="protein sequence ID" value="OBZ80286.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MV29"/>
    <dbReference type="STRING" id="101091.A0A1C7MV29"/>
    <dbReference type="InParanoid" id="A0A1C7MV29"/>
    <dbReference type="OrthoDB" id="2273864at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015074">
        <property type="term" value="P:DNA integration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001584">
        <property type="entry name" value="Integrase_cat-core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050951">
        <property type="entry name" value="Retrovirus_Pol_polyprotein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37984">
        <property type="entry name" value="PROTEIN CBG26694"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37984:SF5">
        <property type="entry name" value="PROTEIN NYNRIN-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50994">
        <property type="entry name" value="INTEGRASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Integrase catalytic" evidence="1">
        <location>
            <begin position="1"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="324"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50994"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ80286.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="324" mass="36934" checksum="C7D634312A77DBB3" modified="2016-11-30" version="1" fragment="single">MHPLKIPTAFDRWHLDFLDLPVTVKGNRWLLVELPVASKEAVADFIYEEIVMRFGVPSEIVTDRGDNFTSGLVDAYLKKVGVNHKLTSAYHPQSNGKVERFNGVIKQMLRKYTNGALHRWDDFVNAALWACCVRVHTTTGYSPFYLTEEREPRLPGDVVQPYIDDATFNDPRTVADHTARELAQLGQHRAAAEFRLKAMAEKDKEKWDGAVKKLSFEPGDLVMLTHEERFGLEPKFKGPYIVVEAYPDYGTYRLQTIAGEPLKSLVHVDRMKPAKGDKPDAPWYDLTFAHRAYNEAMKEALVTPDGFFDKLSNEQATQKLVDDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MVK7</accession>
    <name>A0A1C7MVK7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_11472</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01002075">
        <property type="protein sequence ID" value="OBZ80479.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MVK7"/>
    <dbReference type="STRING" id="101091.A0A1C7MVK7"/>
    <dbReference type="InParanoid" id="A0A1C7MVK7"/>
    <dbReference type="OrthoDB" id="248320at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="62"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="84"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ80479.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="377" mass="41994" checksum="6C47ECB5A16EF45E" modified="2016-11-30" version="1" fragment="single">PTTTSAPTATTTPTTAATLTATTSPLSTAAKTTSSTTTTAPTLTTKPITPISSPSTLAKPASTENTNTPPSNVEPASLSKPAVTSSDSTSAKTTSLEKDKPKMTTVEDGMAKQYESLYLIVDQDIQELKKYQQKLSLMMKSNTTNIETKTKESLAGEDKIWNLSDAAQVGIISDSLLTDARHSLEEMGSVETEVNKIVQNCKATMDKKEDIAFLLNKEVNHNVVDIMDNRDLDEEAKTLLRVLESRSEACSHSLNHMEYKFQENKRRNKIRNDHHNGQLSLYSLHRAVRDVERELVSKSKDIAELETKLADYRLTDSRQKAKRMQLISDDEEEEEEEAKVTTESIQHTTRYLRRYNFMDHVCGQASAQKPVEAHVRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-06-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MVM8</accession>
    <name>A0A1C7MVM8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_11135</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001705">
        <property type="protein sequence ID" value="OBZ80818.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MVM8"/>
    <dbReference type="InParanoid" id="A0A1C7MVM8"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ80818.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="40" mass="4543" checksum="5A00A10F004E1900" modified="2016-11-30" version="1">MSSFVLYTCVPMETIVMTMSLSDYDKIFFSLLETIKATDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MWK5</accession>
    <name>A0A1C7MWK5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DEAD-box RNA helicase Q domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_11113</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001686">
        <property type="protein sequence ID" value="OBZ80836.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MWK5"/>
    <dbReference type="STRING" id="101091.A0A1C7MWK5"/>
    <dbReference type="InParanoid" id="A0A1C7MWK5"/>
    <dbReference type="OrthoDB" id="434041at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ80836.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="50" mass="5520" checksum="9C52D098CB75E7BA" modified="2016-11-30" version="1" fragment="single">MKRSHDVAIDEKVTFDSLIQNKLLIQGLLDCGYEVPSPVQLKAIPLGRLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MWW3</accession>
    <name>A0A1C7MWW3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_10661</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001296">
        <property type="protein sequence ID" value="OBZ81290.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MWW3"/>
    <dbReference type="InParanoid" id="A0A1C7MWW3"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="206"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="213"/>
            <end position="226"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ81290.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="266" mass="31022" checksum="10E55E9618FE7C21" modified="2016-11-30" version="1">MKFSKNSAESLVNSCIMTEEHVVILKQEIAGLRQQMAHFVRCNNILRQYSASAGRVLSQFLGTNIAEEKQVSILGVIQEPRTSQMKVDADVCAVRVKCFFQHWLGMPFLLTLDETQQERLKKKRFLDTTKEYSTNMQNQLAIICENDNVNWQEWTYKNIPVERKLRAYRQLRKFACISDIPTYRCESYWLEKKLIEKFYRHNLEGLSRSNGGNEEDEDDLSWDSELEQLAGQSNEDVEDRLFGEGDEDEGSSSQPPARRRRDDTFN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MWY0</accession>
    <name>A0A1C7MWY0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_10649</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001291">
        <property type="protein sequence ID" value="OBZ81301.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MWY0"/>
    <dbReference type="InParanoid" id="A0A1C7MWY0"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="56"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ81301.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="71" mass="7749" checksum="24D90583DEA11712" modified="2016-11-30" version="1" fragment="single">DGPEASQWAPDSAAVHMRGMDDESPSSEDMELRYEATLSQANDMDLEIPDLERGTTKPTEASVSPLSARRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MYI0</accession>
    <name>A0A1C7MYI0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_10100</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001031">
        <property type="protein sequence ID" value="OBZ81851.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MYI0"/>
    <dbReference type="InParanoid" id="A0A1C7MYI0"/>
    <dbReference type="OrthoDB" id="2426083at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="213"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ81851.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="213" mass="24068" checksum="0EDCA7A6FB244301" modified="2016-11-30" version="1" fragment="single">MILMLYKPEIALTDKKRRNSSNNEQLCIHTKFRYSEVVLYFGFPLLQSLLQRQTFVNNFLGSLQRLVDSHSRRNLSVLGRATVANSLLLSTCWNIFPKVSWKIITTPKSCGGLGILDPTTQQLALFYRWVDGLLFDRPSKTLIQQFLSIHISNCFGSNNVLMCLLFPKARRSLAGSPVSISTLACRVVDVIPRKSYTYIPATLDVLLLPLCAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MYJ0</accession>
    <name>A0A1C7MYJ0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_10043</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001011">
        <property type="protein sequence ID" value="OBZ81907.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MYJ0"/>
    <dbReference type="STRING" id="101091.A0A1C7MYJ0"/>
    <dbReference type="InParanoid" id="A0A1C7MYJ0"/>
    <dbReference type="OrthoDB" id="6600518at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="31"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="93"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="137"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="161"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="187"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="284"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ81907.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="284" mass="32243" checksum="D5C827B406B86276" modified="2016-11-30" version="1" fragment="single">MSYIYYTAAALLVVLSIYKPFISKLDKARSIGLGVASFLAPFIIKYNSLLESNIAFKFSKQWLYSTNLVHSSSSSNETTFDTMQHLTYLNDNVSLMTDAIVLFILAFITASLHGLFTRWQFSITFVRPRANAYFSMFLRYGLSTLNLCLAVMSQKASSHKLSLAFSFFGLLWYLSGPYLIRRWKPAVAVALISAGFSFFVCNTASADSLLYKISFLDWALYTTVLVLVCHSLDHLDALMNTYPYLVEADKEKQCHFQDATSFSYWSHMFYLACNIPSEHELDPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MYL1</accession>
    <name>A0A1C7MYL1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">CCHC-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">A0J61_10455</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001183">
        <property type="protein sequence ID" value="OBZ81496.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7MYL1"/>
    <dbReference type="InParanoid" id="A0A1C7MYL1"/>
    <dbReference type="OrthoDB" id="2287348at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004190">
        <property type="term" value="F:aspartic-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.60.10">
        <property type="entry name" value="Zinc finger, CCHC-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001969">
        <property type="entry name" value="Aspartic_peptidase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005162">
        <property type="entry name" value="Retrotrans_gag_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001878">
        <property type="entry name" value="Znf_CCHC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036875">
        <property type="entry name" value="Znf_CCHC_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46888:SF1">
        <property type="entry name" value="RIBONUCLEASE H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46888">
        <property type="entry name" value="ZINC KNUCKLE DOMAINCONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03732">
        <property type="entry name" value="Retrotrans_gag"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00098">
        <property type="entry name" value="zf-CCHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00343">
        <property type="entry name" value="ZnF_C2HC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57756">
        <property type="entry name" value="Retrovirus zinc finger-like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00141">
        <property type="entry name" value="ASP_PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50158">
        <property type="entry name" value="ZF_CCHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="CCHC-type" evidence="3">
        <location>
            <begin position="443"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="188"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="389"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="457"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="188"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="198"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="398"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="409"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="419"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="466"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="unsure residue" description="D or N" evidence="4">
        <location>
            <position position="520"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OBZ81496.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="544" mass="63593" checksum="521D32E7B681011B" modified="2016-11-30" version="1" fragment="single">HLSLPLREDWKTHFTTVKNRYQALLDYVVNERYTRRQEIDNQRNRIQVITSSINLFPPANRESVQELINQQLQQITVQEQEAQHLDEMIQPEREWLKNELLLALDTIXSYELYDLVQEYDWPTQEVYNDLNLPYDYLLMARRTYRPPKILTEDNDKKIQHTTPEEETIQQLLQRITLLENTLAKTKETTTTQLKQTKPNSETQRQQQDKGQQNVYQERRKRTRLPTFAKGTPEQSQQWIERYEVMCEYLGFSDKERAEELAAILEGPALHWYIGLARTEKADWKTLKKQFLRQHGGGDNPAITALAELKQLRQGNRPMREFGPMIVDLLNRAQIFSAAVQLDYFRDKIHPELLKAVIYRGPTTLMDAINITTEVEMALVSEMGRPSGSSLGMGYATAKPQQSIPEANEQQNYQQHQPQTNKTGNKQYSNKQHQRKHQSTKETRKCYNCNKIGHLSRDCRAPKKQQMGKSNSQQVQSXDKEEENIFAHLVQNNQQEKTSSALRFEANIIPKNQDQQKCLIDTGSTISTIRAETARRLGLYEYSFR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-09-13" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MYY3</accession>
    <name>A0A1C7MYY3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">FAR1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_09928</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000973">
        <property type="protein sequence ID" value="OBZ82023.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="InParanoid" id="A0A1C7MYY3"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="127"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ82023.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="127" mass="14886" checksum="BEECC6A4A08CB5A0" modified="2016-11-30" version="1" fragment="single">MNQEIEPYLKYFNGIASKEYNTKEEIYNDIRQLGKDYNVIFSIKSSKXNMINYICKHGGKKRIRSDREDAVKKTKSQKSLCSAYIVFKLDAFSRKWTVTSHEGHHDSHKISDDPAEYSINRKQTAEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MZ04</accession>
    <name>A0A1C7MZ04_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_10304</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001111">
        <property type="protein sequence ID" value="OBZ81646.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MZ04"/>
    <dbReference type="InParanoid" id="A0A1C7MZ04"/>
    <dbReference type="OrthoDB" id="2104804at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="20"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="45"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="45"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="57"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="474"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ81646.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="474" mass="55562" checksum="4B2BDECEEF078302" modified="2016-11-30" version="1" fragment="single">MTAYTLLEQPSRRNLPKRQWQILIVAVSALLVVLFLASLYKGQEEAETKPSSKHDSTPLSHTPLDTTQPPLRSISFNLSSSNQTHYIDLDRYPLEDQLVQLFGNQTILPSLQHILEGSKNDWLNNKQQADCAQYPLPYPLLRQITQDYLPSLQDQDDFFNVPVKLTQPFVLLPHPNKWLTGQSICIRVVVPYQNKSQDDPYRLMYRPYDQNHQQLTSPWWDTMMTYLVDRHNASIPIHMQPWTGHRILRERARQLNHADPQLPEWARLRADLIYERERLHIYEATVSLKPGQWQFKGLLEFVEGRYNFEFGPVTPYEPLDLPVLPKGHDRWQIVEQAPIESDLDAWMAHKRLPLCQGMHHPGRWLPLPQNLTQSERQQVAVLRNNKYWAPFTCRYRYLSYEAFNRCASNRYAEGMDLYGDSNMRRSIKKFLSHGQWCKDWDKHVTHPLLPDELKPVVQHLDKRAPPTPTPPPPP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MZE9</accession>
    <name>A0A1C7MZE9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Putative urease accessory protein ureG</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">A0J61_09797</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SIMIBI class G3E GTPase family. UreG subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000939">
        <property type="protein sequence ID" value="OBZ82152.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="FunCoup" id="A0A1C7MZE9">
        <property type="interactions" value="20"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7MZE9"/>
    <dbReference type="InParanoid" id="A0A1C7MZE9"/>
    <dbReference type="OrthoDB" id="10063137at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016151">
        <property type="term" value="F:nickel cation binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043419">
        <property type="term" value="P:urea catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05540">
        <property type="entry name" value="UreG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000208">
        <property type="entry name" value="Urease accessory protein UreG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01389">
        <property type="entry name" value="UreG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003495">
        <property type="entry name" value="CobW/HypB/UreG_nucleotide-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004400">
        <property type="entry name" value="UreG"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00101">
        <property type="entry name" value="ureG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31715">
        <property type="entry name" value="UREASE ACCESSORY PROTEIN G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31715:SF0">
        <property type="entry name" value="UREASE ACCESSORY PROTEIN G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02492">
        <property type="entry name" value="cobW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0143">Chaperone</keyword>
    <keyword evidence="4" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="3" id="KW-0996">Nickel insertion</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CobW/HypB/UreG nucleotide-binding" evidence="7">
        <location>
            <begin position="69"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="18"/>
            <end position="44"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005732"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022988"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OBZ82152.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="275" mass="29640" checksum="DC5F01555E778508" modified="2016-11-30" version="1">MTDICRFEEHPSSSAPSAHDHGDGHVHSHGGHDSHGHGHTHEQMDSPGLYQERPKAIYDNRDWSERAFTVGIGGPVGSGKTALMLALCQRLRDKYSLAAVTNDIFTKEDTEFLIRNAALPTDRIAAIETGGCPHAVSVQFGYXEDVSANLNALETLHSKFDTQLLLIESGGDNLAANYSRELADYIIYVIDVAGGDKVPRKGGPGITQSDLLIINKTDLAPIVGADLDVMARDAKKMRGDGPTVFAQVKNGVGMDEIISLILGEWRQSGAAKESL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MZK1</accession>
    <name>A0A1C7MZK1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Acetyl-coenzyme A synthetase</fullName>
            <ecNumber evidence="5">6.2.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">facA_1</name>
        <name evidence="9" type="ORF">A0J61_09783</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>acetate + ATP + CoA = acetyl-CoA + AMP + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:23176"/>
            <dbReference type="ChEBI" id="CHEBI:30089"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.2.1.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the ATP-dependent AMP-binding enzyme family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.2.1.1" evidence="5"/>
    <dbReference type="EMBL" id="LUGH01000936">
        <property type="protein sequence ID" value="OBZ82168.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MZK1"/>
    <dbReference type="FunCoup" id="A0A1C7MZK1">
        <property type="interactions" value="548"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7MZK1"/>
    <dbReference type="InParanoid" id="A0A1C7MZK1"/>
    <dbReference type="OrthoDB" id="1706066at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003987">
        <property type="term" value="F:acetate-CoA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016208">
        <property type="term" value="F:AMP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019427">
        <property type="term" value="P:acetyl-CoA biosynthetic process from acetate"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05966">
        <property type="entry name" value="ACS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.12780:FF:000001">
        <property type="entry name" value="Acetyl-coenzyme A synthetase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="entry name" value="N-terminal domain of ligase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011904">
        <property type="entry name" value="Ac_CoA_lig"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032387">
        <property type="entry name" value="ACAS_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025110">
        <property type="entry name" value="AMP-bd_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_synth/lig_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02188">
        <property type="entry name" value="Ac_CoA_lig_AcsA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF001208">
        <property type="entry name" value="PRK00174.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24095">
        <property type="entry name" value="ACETYL-COENZYME A SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24095:SF14">
        <property type="entry name" value="ACETYL-COENZYME A SYNTHETASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16177">
        <property type="entry name" value="ACAS_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13193">
        <property type="entry name" value="AMP-binding_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56801">
        <property type="entry name" value="Acetyl-CoA synthetase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 5" id="KW-0436">Ligase</keyword>
    <keyword evidence="3 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Acetyl-coenzyme A synthetase N-terminal" evidence="8">
        <location>
            <begin position="39"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="domain" description="AMP-dependent synthetase/ligase" evidence="6">
        <location>
            <begin position="97"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="domain" description="AMP-binding enzyme C-terminal" evidence="7">
        <location>
            <begin position="547"/>
            <end position="625"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU361147"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF13193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF16177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OBZ82168.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="664" mass="73076" checksum="AA2CDD2FFC9EA40C" modified="2016-11-30" version="1">MSQTEEVAQGIEVVTHPVPARLLDASQCPTPHVNSMEQYRTMWKESVEEPTKFFGNLARELLSWDKPFETVNHGSFETGDVAWFLEGELNACYNAVDRHALKNPNKTAIIHEGDEPSSVRHITYGELLRDVCRMANVLKNLGVRKGDNVAIYMPMIPETMIAILACARIGAIHSVVFAGFSAESLLDRVADCGAHVVITSDEGRRGGRNIATKSIVDNALSKQEAHQVEHVIVYQRTGTDVPMQKDRDLWWHEEMAKARPVCPYEKMSAEDPLFLLYTSGSTGAPKGILHTTGGYLLGAAATVKYIFDVHENDIYACMADIGWVTGHSYILYGPLTLGATTVLFESTPTYPTPARFWELIEKHKVTQFYTAPTAIRALQRLGDEWVEKNDLSSLRVIGSVGEPINPEAWNWYNEKVGKGRCAVVDTYWQTETGSIIISPLPGCTPTKAGSATLPFFGIQPVLLDPATGNKIEGPNQTGVLALKNAWPSMARSVYNNHARFLEVYTKPYPGYYYTGDGAAIDEDGYIWIKGRVDDVINVSGHRLSTSEIEAALATHNSVAEAAVVGAHDDLTGQAIHAFVSLKPHAQVIDGLDRELVLTVRKIIGPFAAPKRIHIVREHPKTRSGKIVRRILRKIVNGEHSQLGDTSTLADPSVVSAIVSQVHPN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MZL7</accession>
    <name>A0A1C7MZL7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Midasin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_09683</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000907">
        <property type="protein sequence ID" value="OBZ82273.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MZL7"/>
    <dbReference type="STRING" id="101091.A0A1C7MZL7"/>
    <dbReference type="InParanoid" id="A0A1C7MZL7"/>
    <dbReference type="OrthoDB" id="3937590at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022124">
        <property type="entry name" value="DUF3659"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39461">
        <property type="entry name" value="LEA DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_8G04920)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39461:SF1">
        <property type="entry name" value="LEA DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_8G04920)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12396">
        <property type="entry name" value="DUF3659"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="157"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="31"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="58"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="85"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="186"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="213"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="327"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="340"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ82273.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="340" mass="38221" checksum="67E69FC89DD2406A" modified="2016-11-30" version="1" fragment="single">MKKQAQQQQEAAARAAMQKKLQDQEQNSGSKAREQEDSSNKNETDEIQNSKESKIEQDADDNEDVEDIEEAASDEEVSEKASEVADQEDQEDQDEQGQDEDEQAEEVSDDSEEEESEEEEDYEELFRHMIGKKLNKSGMVVDKKSGAVLGRLVEGKIKKLAGKKIGENGTITNDKGKIVGRVEPVIQDDDDDDSSDDDEDDEQESQQENDVSNPKDDKKGEEASKPLGNDDKKSTGKDNEDQKATKEEEPNDNEDQKATKEEEAKDNEDQTATKEEAKDNNDSKQKGDENSSDEQEDTQKKDEDKEEDSEQEDKPFNPNDAVNEDSPEVRKSGKIVDMED</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MZM5</accession>
    <name>A0A1C7MZM5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">DNA mismatch repair protein MSH5</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">MSH5</name>
        <name evidence="6" type="ORF">A0J61_10074</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the DNA mismatch repair MutS family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001022">
        <property type="protein sequence ID" value="OBZ81876.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7MZM5"/>
    <dbReference type="InParanoid" id="A0A1C7MZM5"/>
    <dbReference type="OrthoDB" id="29596at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140664">
        <property type="term" value="F:ATP-dependent DNA damage sensor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030983">
        <property type="term" value="F:mismatched DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051026">
        <property type="term" value="P:chiasma assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006298">
        <property type="term" value="P:mismatch repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1420.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017261">
        <property type="entry name" value="DNA_mismatch_repair_MutS/MSH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000432">
        <property type="entry name" value="DNA_mismatch_repair_MutS_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007696">
        <property type="entry name" value="DNA_mismatch_repair_MutS_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036187">
        <property type="entry name" value="DNA_mismatch_repair_MutS_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045076">
        <property type="entry name" value="MutS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11361">
        <property type="entry name" value="DNA MISMATCH REPAIR PROTEIN MUTS FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11361:SF20">
        <property type="entry name" value="MUTS PROTEIN HOMOLOG 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05192">
        <property type="entry name" value="MutS_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00488">
        <property type="entry name" value="MutS_V"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037677">
        <property type="entry name" value="DNA_mis_repair_Msh6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00534">
        <property type="entry name" value="MUTSac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00533">
        <property type="entry name" value="MUTSd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48334">
        <property type="entry name" value="DNA repair protein MutS, domain III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00486">
        <property type="entry name" value="DNA_MISMATCH_REPAIR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA mismatch repair proteins mutS family" evidence="5">
        <location>
            <begin position="712"/>
            <end position="728"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006271"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS00486"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OBZ81876.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="878" mass="99478" checksum="A9764E1EC86D9E40" modified="2016-11-30" version="1">MNQANSLMYQYVLVLKNDKNKNNLLICMHALVIAQSSPTLILLPESNVDPLQDLVQQYDGGSIKIQVMPNKDTTFEKGRMLLLNWFIRHIQLDKPDNKSDDQSLAYQNVYLRDPEEGSKTHAYLQLEGLIQLENSHLSVGCAGTILKYLQDVQVGRSLENLSNQDTESVHHLSVQPISIQVFSCQNYMHITSDTLKALCVFDIEANSNTQQKESISLFGISLRRLLNEEELNSFFFFFGTGLLDKTRSVLGKQMLRQWVAHPLQDQKTISDRHKTIRFFSRQVPREKLSEIASLLKHIKNIHRLLSKIKQSKATYSDWQYILKFAYFSIKIIHNMQRIIQDNQNEAENLPLIESFKKISNTSMQEVGAHIDHVIDFESSKEDARIVVKDGIDQELDAMREKYDELDDYLLQVSREISAMLPVSLGAALNVVYFPQLGYLITLPKYHLQHRSSNLTGKNADDNSSVDTELHQQYLAGFQLQFTTADNLYYKNDRTKELDEDLGDIHSMITDKEIEIIQVLSEKVLEYSTDFIDRVKLLSQLDCILSLTLAALKFNYTEPIVTTDSTLKIVRGRHPLQELXMNIFVPNDTHLEGGKGFIDKQDGKLSNVYHANQAQNSRSTTKSDQKISDRVNSVQIVTGANFSGKSVYLKQIALIVYMAHVGSFVPADSAVIGITDKIFARIQTSETVSKPQSAFGYDLQQLNRALRSATNHSLVIMDEFGRGTDCSDGAALFCAVIGYFLSQETQCPRIVASTHFHDLITKNLLSSQDGITLSQTEVLSQPIKEASDQEVGDEVVFLYRIVPGNGYHSSYGTWCASIAGLPSHTVKRAEAKPLNRLDQERKAMFKQLRKLKKQFLETDINEQNPFELIGSMQKLLGNT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MZV8</accession>
    <name>A0A1C7MZV8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">50S ribosomal protein L35</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">A0J61_09596</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the bacterial ribosomal protein bL35 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000887">
        <property type="protein sequence ID" value="OBZ82353.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MZV8"/>
    <dbReference type="FunCoup" id="A0A1C7MZV8">
        <property type="interactions" value="74"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7MZV8"/>
    <dbReference type="InParanoid" id="A0A1C7MZV8"/>
    <dbReference type="OrthoDB" id="162638at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015934">
        <property type="term" value="C:large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.410.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001706">
        <property type="entry name" value="Ribosomal_bL35"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021137">
        <property type="entry name" value="Ribosomal_bL35-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018265">
        <property type="entry name" value="Ribosomal_bL35_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037229">
        <property type="entry name" value="Ribosomal_bL35_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00001">
        <property type="entry name" value="rpmI_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33343">
        <property type="entry name" value="54S RIBOSOMAL PROTEIN BL35M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33343:SF1">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN BL35M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01632">
        <property type="entry name" value="Ribosomal_L35p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143034">
        <property type="entry name" value="L35p-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00936">
        <property type="entry name" value="RIBOSOMAL_L35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="19"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="27"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OBZ82353.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="89" mass="9668" checksum="07A3BCA565EDE178" modified="2016-11-30" version="1">MLGSLASLVTKSLSPLGQASRGMATKLKSHSGAKKRFFPTSNGNYKRWQAGIRHLNSGFSSQRINRLASSKIADNTTKKMLGKALPYSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N007</accession>
    <name>A0A1C7N007_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_09513</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000867">
        <property type="protein sequence ID" value="OBZ82437.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N007"/>
    <dbReference type="InParanoid" id="A0A1C7N007"/>
    <dbReference type="OrthoDB" id="2412974at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="6"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="58"/>
            <end position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ82437.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="82" mass="9495" checksum="0A9D60A284E57FCD" modified="2016-11-30" version="1">MTELSLIQAWIIILTMALIFLSGLCWCFCCGTCVGRSLLRNTGLMRFTRGANTQWQRLPHKPEDENSWQLMTRVDDEESQTQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N0W8</accession>
    <name>A0A1C7N0W8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">GATA-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">A0J61_09164</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000787">
        <property type="protein sequence ID" value="OBZ82785.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N0W8"/>
    <dbReference type="STRING" id="101091.A0A1C7N0W8"/>
    <dbReference type="InParanoid" id="A0A1C7N0W8"/>
    <dbReference type="OrthoDB" id="515401at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000122">
        <property type="term" value="P:negative regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00202">
        <property type="entry name" value="ZnF_GATA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.50.10">
        <property type="entry name" value="Erythroid Transcription Factor GATA-1, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039355">
        <property type="entry name" value="Transcription_factor_GATA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000679">
        <property type="entry name" value="Znf_GATA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013088">
        <property type="entry name" value="Znf_NHR/GATA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10071:SF281">
        <property type="entry name" value="BOX A-BINDING FACTOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10071">
        <property type="entry name" value="TRANSCRIPTION FACTOR GATA FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00320">
        <property type="entry name" value="GATA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00401">
        <property type="entry name" value="ZnF_GATA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57716">
        <property type="entry name" value="Glucocorticoid receptor-like (DNA-binding domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50114">
        <property type="entry name" value="GATA_ZN_FINGER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 6" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="GATA-type" evidence="9">
        <location>
            <begin position="131"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="39"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="179"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="95"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="39"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="182"/>
            <end position="204"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00094"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50114"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OBZ82785.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="363" mass="41292" checksum="B9AA03B91EE7E80A" modified="2016-11-30" version="1">MKGDNYMHYLGDNSDQADLFDKNAFSDLLQQFEPSSISHAQDFTFPSPTLSVDSHQSDQKTSRSNDMANLLDPQFLQHLSSSFHSSRQDGLDQFVQFEEENMTQEDDKEQDLKEKMELLKKNKSAHKPVRSQRQLECFNCHVTKTPLWRRTPDRAHSLCNACGLYYKQYNTHRPLHIRQKHQSNQTKQAAAAASLSTAPSSPQQDKVMPMNIDLEQTEEQSASVCQHCHHARSSLVNDVGQAVCNTCHLLANIPVIGQKRNSTDALMEENPGDESNKMQRLLQQQSLVFPSIVVPNSNEPVPSVLQRQPEEPSGQHDDTRFKSLIARMSVQQMEGFLSMLERRCDILRSIIRNEGDNDNSITI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N1I9</accession>
    <name>A0A1C7N1I9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">40S ribosomal protein S18</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">RPS18_0</name>
        <name evidence="6" type="ORF">A0J61_08988</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the universal ribosomal protein uS13 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000750">
        <property type="protein sequence ID" value="OBZ82960.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N1I9"/>
    <dbReference type="STRING" id="101091.A0A1C7N1I9"/>
    <dbReference type="InParanoid" id="A0A1C7N1I9"/>
    <dbReference type="OrthoDB" id="5534642at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015935">
        <property type="term" value="C:small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="4.10.910.10:FF:000002">
        <property type="entry name" value="40S ribosomal protein S18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.910.10">
        <property type="entry name" value="30s ribosomal protein s13, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027437">
        <property type="entry name" value="Rbsml_uS13_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001892">
        <property type="entry name" value="Ribosomal_uS13"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010979">
        <property type="entry name" value="Ribosomal_uS13-like_H2TH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018269">
        <property type="entry name" value="Ribosomal_uS13_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10871">
        <property type="entry name" value="30S RIBOSOMAL PROTEIN S13/40S RIBOSOMAL PROTEIN S18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10871:SF3">
        <property type="entry name" value="SMALL RIBOSOMAL SUBUNIT PROTEIN US13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00416">
        <property type="entry name" value="Ribosomal_S13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002134">
        <property type="entry name" value="Ribosomal_S13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46946">
        <property type="entry name" value="S13-like H2TH domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00646">
        <property type="entry name" value="RIBOSOMAL_S13_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50159">
        <property type="entry name" value="RIBOSOMAL_S13_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 6" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="83"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003830"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OBZ82960.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="102" mass="11938" checksum="2BE983BEF2D0C5E1" modified="2016-11-30" version="1" fragment="single">DLTKRAGELSSEELERIVTILQNPAQYKIPNWFLNRQKDIVDGKSSQVISNVLDTKFREDLERLKKIRNHRGLRHYWGVRVRGQHTKTTGRRGRTVGVSKKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N201</accession>
    <name>A0A1C7N201_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Sphingosine kinase 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">SPHK1</name>
        <name evidence="2" type="ORF">A0J61_08883</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000728">
        <property type="protein sequence ID" value="OBZ83067.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N201"/>
    <dbReference type="InParanoid" id="A0A1C7N201"/>
    <dbReference type="OrthoDB" id="336240at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001727">
        <property type="term" value="F:lipid kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046512">
        <property type="term" value="P:sphingosine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.200.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10330">
        <property type="entry name" value="Probable inorganic polyphosphate/atp-NAD kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017438">
        <property type="entry name" value="ATP-NAD_kinase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001206">
        <property type="entry name" value="Diacylglycerol_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050187">
        <property type="entry name" value="Lipid_Phosphate_FormReg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016064">
        <property type="entry name" value="NAD/diacylglycerol_kinase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12358:SF108">
        <property type="entry name" value="DAGKC DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12358">
        <property type="entry name" value="SPHINGOSINE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00781">
        <property type="entry name" value="DAGK_cat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00046">
        <property type="entry name" value="DAGKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111331">
        <property type="entry name" value="NAD kinase/diacylglycerol kinase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50146">
        <property type="entry name" value="DAGK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="DAGKc" evidence="1">
        <location>
            <begin position="118"/>
            <end position="263"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ83067.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="473" mass="53222" checksum="B207951AB401045D" modified="2016-11-30" version="1">MTRSATVKNKEDSLIYLYLNEDHLEIEHKNNNTKELVSFSSIYGVLYQDDLHEITIHLASSFDPNSLSEIPDNPDLNNLRPKQVQWVQRTLTYIAADDHLCSMAAELKTQCLPHQTTFASTPIFVILNPTSGQQLAEKHFKDTVKPMLMTAGFQTVEKVLTESNGRTRGIAESIGKRLSSYTTPPIIVAMGGDGTLHEVINGLADAEGALSEHVRFRLGVIPAGSGNAFAIGLGIESIEHATLKIIHAKQEKPFYLMDVRFGRATQDTEWSHHVVYDKMERPIRLLVVMSWGFHAQIVSKSRYLRYFMGNQRFSLVAMFLLKFLQQYEGEVVLKQVKQYDSVNEAWPDSVQEEMVLGTDKRFTYFIASKQHSLEKGFKIAPHASSLQKDIDIVTLRDVNAETLTNASIGAFQGGKHIASSQVDYFKANELLLRVPYKTELCLDGEIHNLSAKGIIHLKVIESSTDRCQFTVFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N236</accession>
    <name>A0A1C7N236_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">FHA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_09196</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000795">
        <property type="protein sequence ID" value="OBZ82756.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N236"/>
    <dbReference type="InParanoid" id="A0A1C7N236"/>
    <dbReference type="OrthoDB" id="2232050at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.200.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000253">
        <property type="entry name" value="FHA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008984">
        <property type="entry name" value="SMAD_FHA_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00498">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49879">
        <property type="entry name" value="SMAD/FHA domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FHA" evidence="1">
        <location>
            <begin position="29"/>
            <end position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00498"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ82756.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="91" mass="10176" checksum="5BD6C27165FEA0D1" modified="2016-11-30" version="1">MSIQNLATQETFPLAVGSTITLGRGSHGIHSPYISRKQVEITYLDDHRCFVKKVSDRIMLLNDAALPFQQEFQLKNGDVLGFPISNEAEVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N268</accession>
    <name>A0A1C7N268_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Transmembrane 9 superfamily member</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">TMN7</name>
        <name evidence="10" type="ORF">A0J61_08744</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Golgi apparatus</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 9">Belongs to the nonaspanin (TM9SF) (TC 9.A.2) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000703">
        <property type="protein sequence ID" value="OBZ83203.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N268"/>
    <dbReference type="STRING" id="101091.A0A1C7N268"/>
    <dbReference type="InParanoid" id="A0A1C7N268"/>
    <dbReference type="OrthoDB" id="1666796at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072657">
        <property type="term" value="P:protein localization to membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004240">
        <property type="entry name" value="EMP70"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10766:SF55">
        <property type="entry name" value="TRANSMEMBRANE 9 SUPERFAMILY MEMBER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10766">
        <property type="entry name" value="TRANSMEMBRANE 9 SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02990">
        <property type="entry name" value="EMP70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 9" id="KW-0732">Signal</keyword>
    <keyword evidence="4 9 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008810979" description="Transmembrane 9 superfamily member" evidence="9">
        <location>
            <begin position="18"/>
            <end position="623"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="241"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="300"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="342"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="374"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="409"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="499"/>
            <end position="521"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="533"/>
            <end position="552"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="564"/>
            <end position="587"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="10">
        <location>
            <position position="623"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005227"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU363079"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OBZ83203.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="623" mass="70767" checksum="4F803BFC6C32CA59" modified="2016-11-30" version="1" fragment="single">MIIGIVLSLLLCPFVLAYKPGDSIPIYYNKIFSLSNPLTYSYDALSFVCPMQHSSRQKSSLIFDQDLRGDRTIQSDYKINFLENQECKLLCRQAWRVEDAIQAEELTSGNYFAEWELDGMPGATVSYTNEAPEHNYRVGFPLGFKKDESAFINNHVIFQVLYTPSENQADEYDIVGFEVYPDSIADGECTKKTVEYENQEITANKLRVTYTYSVQWKKVEAPLNNRWDAFLLRPNPDRHHYALLNGVAIVLCTFVILIIISLKTVQKESTTDDKDLKVYDDADEIAGWRLISRDVFRRPVYGGLLTPLLGSGIQLISVLVGLMICLQFGWYHPAQPRSLIHWFTFLFILSSVPGGYCSARVYKVFRGRSWTLNSVLTALAFPSIALLVLLIVGVLAWPQQSSLAISFSGWMSFILVWTILVLPLITLGAYYGQKADRIEYPSRTTQIPRAIPAKSWYHTNSIRALTIGMIPFAIIFLNWHELLNSICKGEYTLSISDTVRILVLMLIAVMQTTVISIFLQLCAEDYHWWWQSFTVGASPAVYMLVYGWFYYLKNSEIQGILGGTIYFLYLLLGCSIIGACTGTLGFISAYTPLLLCQDGLEDHISEIFVHNKVHFSKKSHQNV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N3A1</accession>
    <name>A0A1C7N3A1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Ectopic P granules protein 5</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">EPG5</name>
        <name evidence="5" type="ORF">A0J61_08454</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the EPG5 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000652">
        <property type="protein sequence ID" value="OBZ83497.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N3A1"/>
    <dbReference type="STRING" id="101091.A0A1C7N3A1"/>
    <dbReference type="InParanoid" id="A0A1C7N3A1"/>
    <dbReference type="OrthoDB" id="75419at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097352">
        <property type="term" value="P:autophagosome maturation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051436">
        <property type="entry name" value="Autophagy-related_EPG5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058750">
        <property type="entry name" value="TPR_Epg5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31139">
        <property type="entry name" value="ECTOPIC P GRANULES PROTEIN 5 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31139:SF4">
        <property type="entry name" value="ECTOPIC P GRANULES PROTEIN 5 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26573">
        <property type="entry name" value="TPR_Epg5_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0072">Autophagy</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Epg5-like TPR" evidence="4">
        <location>
            <begin position="963"/>
            <end position="1085"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1132"/>
            <end position="1157"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="1137"/>
            <end position="1153"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010948"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF26573"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OBZ83497.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="1187" mass="137890" checksum="86F945B2376CB34D" modified="2016-11-30" version="1">MDKELESLITKYKQSLDQLSEINHKAQEVNDSEQAIVHHLSKKHEAEEKLNQIISKLRLDVDHLLSKRQSETNAAKLAVDTYLHTIVWNLFSRTELQNEKLLFNQDQNRLSDKKCLLKLITTLFQFDQHHENTEYITQLHLWMTGLITIYLRLCSSNEKKKILQLLKGTSHISPWAIPLIQFHASDITDAENYIEILDIIFFNQETDETPTWTEDDFLAVMDQLAIDFHYSKMMESIGPDEPPHLLFEFSRTMTDSLLKAIKRFGSMKSLTKRLSQTVIQLALLLVEGTEERGWDCQEQIDQFLCSLVYSFYDLKKDGWFFLPNIPYKVLSMEALWQVTTHLLQMEDRTVPISLDLVLNEHLPNITRFQYELHDNQNQGVFMLSCLTNIVTCIPPGVDEISSMRDPEGMLSACIIAVIAYTLFNVAFIDKLLRELFYRDVRDNLRPICRCHPFIISLLFRWTVQHMATMERMALYLFHSIHLEDWVILKDDLTLLHKLLTVPSSCPSLTTQQLAQIQLARYVIEHLNYGYRHNSIDLVCSKSQPWSQRKVPFLSYETHEEIAFILLDACQKFQPIVENQESNNNIKGTMELVGTVMSNYYTPIADQLLKSPYLPINNHQHVHSKEGMAAEFIDWAWFVAIQLRLYDCPISPRATDIEASIDLPFIKAVLNSFNPVSSSHSALIIYIAFSLSVTSRHFLRFSSNEGWMKLWTILKRGKPEAVIQILSDIIPSFVYMHGDDFFNDESLTDLFRHLIEFKPDPMLTKAARQYLQRHKTTMNMSGIGLILGSTVWQAHLIDQTSQLMDDQGKGFSYVDLVLHSWFKTIFRKADWIWQASYISLVEQLCQLGFVVHRHRLVCQMLTEESKRLELAKQNSTSGPPRLARLMKNVMLMPDGPFASLLVGEWSVLKSNTKAPGVEQQYHWFSLYALLSETLEEASLRAEIVSAVHEECTDITTVYKTISKKPIEYFSLYRWLHHILIVPMDHPLLPLYFQMFFSLYYQLAGPHQTLGSLFFQQRPDALVELRNRIASIQTYYGQKMMTDLSTAEIQQQFYYAIWLWLGNEELSTGQLEIKELPSHYDKQRLSSCYAKEDEKEQPWHTHSFWLDLVNTHQLEQDFLLFPWQSAEKFRTTETTQGRLLTHSSSHSIQQTTSSLGDQASLSTHARRLRMLTDESTIEPLPPILIQKPT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N3I0</accession>
    <name>A0A1C7N3I0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">60S ribosomal protein L26-1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">RPL26A_1</name>
        <name evidence="6" type="ORF">A0J61_08311</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uL24 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000628">
        <property type="protein sequence ID" value="OBZ83641.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N3I0"/>
    <dbReference type="FunCoup" id="A0A1C7N3I0">
        <property type="interactions" value="543"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N3I0"/>
    <dbReference type="InParanoid" id="A0A1C7N3I0"/>
    <dbReference type="OrthoDB" id="1688503at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015934">
        <property type="term" value="C:large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06089">
        <property type="entry name" value="KOW_RPL26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.30.30:FF:000009">
        <property type="entry name" value="60S ribosomal protein L26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005824">
        <property type="entry name" value="KOW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014722">
        <property type="entry name" value="Rib_uL2_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005825">
        <property type="entry name" value="Ribosomal_uL24_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005756">
        <property type="entry name" value="Ribosomal_uL24_euk/arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041988">
        <property type="entry name" value="Ribosomal_uL24_KOW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008991">
        <property type="entry name" value="Translation_prot_SH3-like_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01080">
        <property type="entry name" value="rplX_A_E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11143">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L26 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00467">
        <property type="entry name" value="KOW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16906">
        <property type="entry name" value="Ribosomal_L26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00739">
        <property type="entry name" value="KOW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50104">
        <property type="entry name" value="Translation proteins SH3-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01108">
        <property type="entry name" value="RIBOSOMAL_L24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 6" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="KOW" evidence="5">
        <location>
            <begin position="48"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00739"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OBZ83641.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="129" mass="14683" checksum="AC66C12A8AD2C5FF" modified="2016-11-30" version="1">MKFSADVSSSRRKSRKAHFSATSDVRRKIMSAPLSKELREKHSVRSIPVRKDDEVMVVRGTYKGREGKIVQVYRKKWVIHIDRVAREKVNGATAPIGISPSKVVVTKLKLDKSRVAILERKGKKEAMKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N3Y9</accession>
    <name>A0A1C7N3Y9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_08192</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000609">
        <property type="protein sequence ID" value="OBZ83757.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N3Y9"/>
    <dbReference type="InParanoid" id="A0A1C7N3Y9"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="184"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="16"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="184"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="197"/>
            <end position="220"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ83757.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="246" mass="28303" checksum="9C546DBF4AB24312" modified="2016-11-30" version="1">MPRSNSTFQNKVLRKLDDILNEMKSLRASIKNLEDRLNALKYHKNDEIQDMEENASIIPCPTKVSRVSGNLVRRKPIADDIKNALIELIPSVPVEEIYISVVKYCTTRSDEVVETFYNNKPPTWKHVPASTKAKMYIDAIKLIAKKHGVNMKRCENNWLVKSLVYTGYQNRFQALCRSTVKDRNINDDDKSKRKSDEEENEDEGEETDEETESDSEDDEVVVSQPQKRKSKQASGKVSRSHKKAKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N460</accession>
    <name>A0A1C7N460_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">protein disulfide-isomerase</fullName>
            <ecNumber evidence="3">5.3.4.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">A0J61_08099</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 11">
            <text>Catalyzes the rearrangement of -S-S- bonds in proteins.</text>
            <dbReference type="EC" id="5.3.4.1"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Endoplasmic reticulum lumen</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.3.4.1" evidence="3"/>
    <dbReference type="EMBL" id="LUGH01000594">
        <property type="protein sequence ID" value="OBZ83851.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N460"/>
    <dbReference type="FunCoup" id="A0A1C7N460">
        <property type="interactions" value="85"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N460"/>
    <dbReference type="InParanoid" id="A0A1C7N460"/>
    <dbReference type="OrthoDB" id="427280at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005788">
        <property type="term" value="C:endoplasmic reticulum lumen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003756">
        <property type="term" value="F:protein disulfide isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015035">
        <property type="term" value="F:protein-disulfide reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034976">
        <property type="term" value="P:response to endoplasmic reticulum stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd03002">
        <property type="entry name" value="PDI_a_MPD1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057305">
        <property type="entry name" value="Thioredox_PDIA6_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45815">
        <property type="entry name" value="PROTEIN DISULFIDE-ISOMERASE A6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45815:SF3">
        <property type="entry name" value="PROTEIN DISULFIDE-ISOMERASE A6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24541">
        <property type="entry name" value="Thioredox_PDIA6_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00085">
        <property type="entry name" value="Thioredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00421">
        <property type="entry name" value="THIOREDOXIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5" id="KW-0413">Isomerase</keyword>
    <keyword evidence="6" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008889465" description="protein disulfide-isomerase" evidence="7">
        <location>
            <begin position="23"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="domain" description="Thioredoxin" evidence="8">
        <location>
            <begin position="8"/>
            <end position="147"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001182"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004319"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OBZ83851.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="420" mass="47463" checksum="5158C3FD07C23FC3" modified="2016-11-30" version="1">MKVQYLSTTLLTIWANLALTHAFYGPRDDVVELTPRNFKSALLDTNHLVAVEFYAPWCGHCQRLAPEWKKAATNLKGLVSVAAINCDEDNNKGLCAQYDIKGFPTIKVFSPELRKNKRTGELTKSASDYQGPRDAKSIVDHLLSYQPSQVLFVKWNEKDVKSKKSISLDNFLITKNETLPKALLFTNKPTTTPLYKALSIDFKDKMLVGEVKSSEKNIIAEFGIQSFPTLLVISPEHGSVQFEGKLNHQNLKEFMKKYALSSHSSSEKQSPVKSAVEEPKPVVALEDNDSFAKSCLKASTSTICIVAITNQDDKQDTVDMLNTLRNRFTPSNGLDFQFAWLYADQSQSITNSLQVPQDSPSIFFLRPSKQLYRNYIGSWSEQNLLNWLNQINTGRVQAWTYKDDLKVDLKPVDEPIHDEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N4M8</accession>
    <name>A0A1C7N4M8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Nitrogen assimilation transcription factor nirA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">nirA_2</name>
        <name evidence="9" type="ORF">A0J61_07854</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000556">
        <property type="protein sequence ID" value="OBZ84095.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N4M8"/>
    <dbReference type="STRING" id="101091.A0A1C7N4M8"/>
    <dbReference type="InParanoid" id="A0A1C7N4M8"/>
    <dbReference type="OrthoDB" id="2406834at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051615">
        <property type="entry name" value="Transcr_Regulatory_Elem"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31313">
        <property type="entry name" value="TY1 ENHANCER ACTIVATOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31313:SF81">
        <property type="entry name" value="TY1 ENHANCER ACTIVATOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Xylanolytic transcriptional activator regulatory" evidence="8">
        <location>
            <begin position="301"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="63"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="67"/>
            <end position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OBZ84095.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="742" mass="83760" checksum="0C1DF83C952AFA42" modified="2016-11-30" version="1">MSNEEDQVRWKTALYAARRRKCMYLKNNDETYIRLDPVDEPTPNVSAIAESYLQDMNRQLRQKQHLAPSSSTTTATAVTPDHDSPKIFAADKPDNLFACHQEQIESIGSSNSPSLMQPATRPDKMMEQLTDGLVRLTLHHDSSKLGSENVTPWRTYGEFVRWTPEPQLPHYYTSSIDMPSRPLQEQLIKVFFDECYYILPILSRSMFYDQLKVKGSLITPLLLNAIYAHAAKHNHQHPAFCSDTTQQNGDLFYNRARRLVDDFLDVPRISTVIALLYMALYDCDSTSQNSQGRPKVRSSRTWMYSGMAIRMCLELGLHTANYSSQMSQFDIELRKRVLWTCFVMDKLESCTMERPWMLKSKDIALDFPTPLPEDSAQERLVLEGFSQLCRLMVLMEKIIHFFTYDIKNLSLWTMSEESQIMHFLDAIHQWREILPAELKWTTPATNPGVQQYIPLVPSSAVVLNLHLICYDLELSLIMCCRYQDEHLQRERRRTLANTITHIVSITVQHPHLMYNFAVSTFSGVFAALTHAADFSNPRLDISESAKMQFRKSLEDVRATVEQIPMRDLGNFARLVDLTLQPNGIATPNHVTLNSISIPSSYVSAFSAISDMCHKEDAGVSEAIQTTMEHHLYPRTDALDNRSGYGSVSPERHGSPFHPNNTNLMISGQFAFDACYQPQSSSHSSPSGSVSAAAVAAAAAAVGAVGTPSASSSSHHGAKSIEPADYTFELISVGDEWARSLIY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N4V5</accession>
    <name>A0A1C7N4V5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_07902</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000563">
        <property type="protein sequence ID" value="OBZ84048.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N4V5"/>
    <dbReference type="InParanoid" id="A0A1C7N4V5"/>
    <dbReference type="OrthoDB" id="2443930at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ84048.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="68" mass="7991" checksum="7B0BE669EA52A310" modified="2016-11-30" version="1" fragment="single">MHHALNRLSLLFQRQHEERHVREERSKRVRGSSDGCIQMKDAQARINLNIANPATGCQKLIEIEDERR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N4W2</accession>
    <name>A0A1C7N4W2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="9">26S proteasome non-ATPase regulatory subunit 14</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">RPN11</name>
        <name evidence="9" type="ORF">A0J61_07789</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase M67A family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000547">
        <property type="protein sequence ID" value="OBZ84162.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N4W2"/>
    <dbReference type="FunCoup" id="A0A1C7N4W2">
        <property type="interactions" value="827"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N4W2"/>
    <dbReference type="InParanoid" id="A0A1C7N4W2"/>
    <dbReference type="OrthoDB" id="605656at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034399">
        <property type="term" value="C:nuclear periphery"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008541">
        <property type="term" value="C:proteasome regulatory particle, lid subcomplex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034515">
        <property type="term" value="C:proteasome storage granule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140492">
        <property type="term" value="F:metal-dependent deubiquitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000266">
        <property type="term" value="P:mitochondrial fission"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016559">
        <property type="term" value="P:peroxisome fission"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032436">
        <property type="term" value="P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043248">
        <property type="term" value="P:proteasome assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902906">
        <property type="term" value="P:proteasome storage granule assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043161">
        <property type="term" value="P:proteasome-mediated ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016579">
        <property type="term" value="P:protein deubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd08069">
        <property type="entry name" value="MPN_RPN11_CSN5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.140.10:FF:000001">
        <property type="entry name" value="26S proteasome non-ATPase regulatory subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.140.10">
        <property type="entry name" value="Cytidine Deaminase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000555">
        <property type="entry name" value="JAMM/MPN+_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050242">
        <property type="entry name" value="JAMM_MPN+_peptidase_M67A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037518">
        <property type="entry name" value="MPN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056263">
        <property type="entry name" value="RPN11_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10410">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 3 -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01398">
        <property type="entry name" value="JAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23594">
        <property type="entry name" value="RPN11_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00232">
        <property type="entry name" value="JAB_MPN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102712">
        <property type="entry name" value="JAB1/MPN domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50249">
        <property type="entry name" value="MPN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="6 9" id="KW-0647">Proteasome</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="MPN" evidence="8">
        <location>
            <begin position="34"/>
            <end position="169"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008568"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OBZ84162.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="312" mass="34813" checksum="995176C662B5C743" modified="2016-11-30" version="1">MERLQRLFGSAAAGLGQGTQPGMDTPTVDNAEMVYISSLALLKMLKHGRAGVPMEVMGLMLGEFVDDYTVRVIDVFAMPQSGTGVSVEAVDPVFQTKMLDMLKQTGRPEMVVGWYHSHPGFGCWLSSVDINTQQSFEQLNPRAVAVVVDPIQSVKGKVVIDAFRLINPQTVMLGQEPRQTTSNIGHLNKPSIHALIHGLNRHYYSIAINYRKNELEEKMLLNLHKKDWTDGLTLENFTEHTEVNEKSVSHMLTLAEAYNKSVQEELTLTPEQLKTRHVGKQDPKRHLEDKVESVMGNNIVMALGTMIDSVSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N575</accession>
    <name>A0A1C7N575_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">GATA-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">A0J61_09466</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000856">
        <property type="protein sequence ID" value="OBZ82484.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N575"/>
    <dbReference type="STRING" id="101091.A0A1C7N575"/>
    <dbReference type="InParanoid" id="A0A1C7N575"/>
    <dbReference type="OrthoDB" id="2162994at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00202">
        <property type="entry name" value="ZnF_GATA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.50.10">
        <property type="entry name" value="Erythroid Transcription Factor GATA-1, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000679">
        <property type="entry name" value="Znf_GATA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013088">
        <property type="entry name" value="Znf_NHR/GATA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47172:SF24">
        <property type="entry name" value="GATA ZINC FINGER DOMAIN-CONTAINING PROTEIN 14-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47172">
        <property type="entry name" value="OS01G0976800 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00320">
        <property type="entry name" value="GATA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00401">
        <property type="entry name" value="ZnF_GATA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57716">
        <property type="entry name" value="Glucocorticoid receptor-like (DNA-binding domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50114">
        <property type="entry name" value="GATA_ZN_FINGER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="4" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 6" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="GATA-type" evidence="7">
        <location>
            <begin position="341"/>
            <end position="376"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00094"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50114"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OBZ82484.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="393" mass="44587" checksum="8807316346FAE4EC" modified="2016-11-30" version="1">METSLLPQPKKINAQCQNHLIPGNQDNWEVLDIVLYTITDNVLLAFFHSAEPTSQCRLKNSLLASGVTCDASVQKTFTQQDGESLRNILNSTHQSYSTHLAQTPLRIFTIAGQTQNAPLIFHWSSLNPDDTSMLEEARRISKTLHAREYKSTSFKAEGPQPWKTILNTETNCSRHSHTSDTVQFLFTNCSFERISIPYGDVVFESYQIIPLFTHSSHRNSLCRPQPSLMITESISSRSTSPLGTVVELPSPLLLLDHHEKNSTCYVAGTTEINDPHTRQTTHDPIQSNKPMSALFQKFRVYSNPPVHLIPQDADSKRYPIDKRDRFFNRKYGCPIGDGLVPNSTKICVRCHTSNSPEWRRGPDGNKTLCNACGLRYSRLKSKQWKLMDHFNKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N597</accession>
    <name>A0A1C7N597_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">PH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">A0J61_07647</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000528">
        <property type="protein sequence ID" value="OBZ84305.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N597"/>
    <dbReference type="InParanoid" id="A0A1C7N597"/>
    <dbReference type="OrthoDB" id="2123378at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052007">
        <property type="entry name" value="Bud4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001849">
        <property type="entry name" value="PH_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36100">
        <property type="entry name" value="BUD SITE SELECTION PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36100:SF1">
        <property type="entry name" value="BUD SITE SELECTION PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50003">
        <property type="entry name" value="PH_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="repeat" description="ANK" evidence="1">
        <location>
            <begin position="115"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="domain" description="PH" evidence="4">
        <location>
            <begin position="1697"/>
            <end position="1813"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="156"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="262"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="315"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="543"/>
            <end position="578"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="632"/>
            <end position="655"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="685"/>
            <end position="707"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="722"/>
            <end position="790"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="859"/>
            <end position="885"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="995"/>
            <end position="1035"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1102"/>
            <end position="1135"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="224"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="156"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="176"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="198"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="286"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="342"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="386"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="543"/>
            <end position="555"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="635"/>
            <end position="655"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="691"/>
            <end position="702"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="741"/>
            <end position="763"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="772"/>
            <end position="789"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="859"/>
            <end position="879"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="1014"/>
            <end position="1031"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="1120"/>
            <end position="1135"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OBZ84305.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="1824" mass="205299" checksum="D347CC5AC287B245" modified="2016-11-30" version="1">MTGFEIDEALLLDWTTAIEALDFDTIQELYELQPQLLWTALQPVHLESDFAHFIQRLESFRVLGTSLRPVYPLHHILFDYGVPGDEWASDRSVLVDFILKNTTGNELNSCLWGAEENTTMHLAYLLNQPNLTQQLIEKGALANTPNKLGHLPMKEEQLEKNNDDQPKLLINKSKPTSKEKVPVSTSDRFRRLRELAESPNNKGNKTTTGRQNSTRRYFRPGHLEEKKRRILNEEEEELEKQKLKRQKDIELLAQRSAVKNNPLFKKLEGQNQKVEQKPAGPSVSTIRDRQKLLKGDEQIKRSSRVINSLKNSSYVSSSVFRQTQPSEDKNTNAPPLAKLRLASKESVVDSKEENSNATSSQKSQTDKDSIIDEDVSDNASTKSKKSALSLKVNNENNKSSTSLSLSSPTASLKSNSTSLFSPSESSFALKNTTSTSLSLKSPTNASFDNTNLSDLGSAVTDEELDLLNIGKMRELNVPTKSAQEKKLVDIGPVNIKNIVDMHEQHNVKEEIEIHTIGRKFEVWKKDARTVEELEDDSIISRKKDTDASSLEKQRLENLPLEKQSLEKQPLENNHSTVNCEAISSKIDIQTTDQKSVTETDTKSLASIQTETSSVADIDTASIKSRSEESVVLEQDVTHDASMSDRPEAVKKKPDVVDQTQFKKDLKLLEKRAENTTTKIEMHERAIEASVKHKPTKPKKLKSLKLGPEALNQKRALFNQRMAAEPMPTRRFEESNASAISEESDEDEDEDEDDDDEDDDDDEYSQPGDIIRSTSSSTSTASSYSKSASTPVVIDNSFGDAQIADDHTTHHFQALHQNETVKLFETHTDSNNNSKTVQYIPISQIEPLRTLDSISQSETIHVDSNSNTENLPTDIPTNENNRSRDIPRDNVTEAKAKRESFEPLSINTSASADVATHIEEEEDAVTPTLASVNALHDETTAATEPAALHEAPELDDSKSNDLDLNYEHFIKQQERGVDLESEVDTAYSSNELLDTYHNQQPPAHENKPMVASADKTNEDSHISEASHIRHDQQPMPLHRISAISEATTSSDQWFDPDDSWVEQQRKSALLAGFGAHASQDISRNDQHRDSDLSSIVSDEYYYKRSSSTDHTGLDDDLDNDSYSHMDSEKLNSTQLKKEEATAIQPFTHEDTYVQSSAYENISVQPTTYENINTKSAAYENIDVKSSAYENKNTQSFTRVDTEVQAPARVHTDTQISTREIADAQSSTLKNIGIQSSLQEDKDLHSTTQESASPKPPVKIFTSADVFDEDDYYSTQLHTEAASYSQKTTMTGSIASSGTQMPAVEERVKSRVYLGNQEEEGEITVFMDPSDQQSVKSSPISSTDHNHLGVFHQPNVSTASLVSQRGQYLAVKQEDDSSPPAMIQVPSRTVPIIDHKTEQEYVPHDPNNPRVEDISHYMNTLPTLNKNNHEITGSSAFDTSASFNSNEESMTKHAISMTPSARPVVLEDSRGIPNAHEMDFKPIPEECLSSSEESKVSFEVSQYGKMYIGVSGAHSVLLPLPKEITYVRCVISDGEFEYVSRYXIXGPQILMDYECCVDVRPGTIITVSLLVRPDFHVKPKTGWGRLFTSIRKQKEHLSGYVHPEDGAIGQTRFAVDHMVSGCYKKTYEAYFDCFNSWYARTNRERARREQYGDDEDFLKIIGKMNIEMLYLPVSSPHVRVPKSLRECDLTLKIRQWHDTCWQSGYLSTRCQGKKIWERHFYRLIGSQLIGHEQATDNIWDHYNIADVIRLSAAADKVIVTLVEDDDSKVFGDKTIHDYGQKGFFRLQFPNYYLDCVSDSLEESEEWVKTLKSMIGRVPLKLPFMEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N5B5</accession>
    <name>A0A1C7N5B5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">ER lumen protein-retaining receptor</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">KDELR2</name>
        <name evidence="12" type="ORF">A0J61_07612</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 11">Endoplasmic reticulum membrane</location>
            <topology evidence="1 11">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the ERD2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000523">
        <property type="protein sequence ID" value="OBZ84335.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N5B5"/>
    <dbReference type="FunCoup" id="A0A1C7N5B5">
        <property type="interactions" value="223"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N5B5"/>
    <dbReference type="InParanoid" id="A0A1C7N5B5"/>
    <dbReference type="OrthoDB" id="7694678at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046923">
        <property type="term" value="F:ER retention sequence binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006621">
        <property type="term" value="P:protein retention in ER lumen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016192">
        <property type="term" value="P:vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000133">
        <property type="entry name" value="ER_ret_rcpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10585">
        <property type="entry name" value="ER LUMEN PROTEIN RETAINING RECEPTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00810">
        <property type="entry name" value="ER_lumen_recept"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00660">
        <property type="entry name" value="ERLUMENR"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00951">
        <property type="entry name" value="ER_LUMEN_RECEPTOR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00952">
        <property type="entry name" value="ER_LUMEN_RECEPTOR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 11" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="6" id="KW-0931">ER-Golgi transport</keyword>
    <keyword evidence="9 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 11" id="KW-0653">Protein transport</keyword>
    <keyword evidence="10 11 12" id="KW-0675">Receptor</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 11" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="56"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="97"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="119"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="150"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="180"/>
            <end position="199"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010120"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU000634"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="OBZ84335.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="212" mass="24935" checksum="C55C51AA3C15328A" modified="2016-11-30" version="1">MNIFRLTADLTHLASILILLHKIQKTKSCAGISFKSQLLYSLVFITRYLDLFVKHFSIYNTLMKLFFIGSSLFIVYLMYHKYHATYDASFDTFHTEYLILGALVAGFASTYLYTTIEILWSFSIWLESVAILPQLFMLQKTGEAETITTHYLFALGAYRTLYLLNWIYRYMDEGYTDWVAWVAGMVQTVLYSDFFYIYYVKVLHGEKFELPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N5U3</accession>
    <name>A0A1C7N5U3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_07579</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000519">
        <property type="protein sequence ID" value="OBZ84371.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N5U3"/>
    <dbReference type="STRING" id="101091.A0A1C7N5U3"/>
    <dbReference type="InParanoid" id="A0A1C7N5U3"/>
    <dbReference type="OrthoDB" id="2439595at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="13"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="53"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="84"/>
            <end position="148"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ84371.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="468" mass="53051" checksum="F7515103878CD8A8" modified="2016-11-30" version="1">MSAPSSELPATVNAGNKQAASNPKKTDSAIVSSTLAKEPEKHELTQENTDATQAQQSQLQSQQPANVQQEPQIQQRSQQKDQEQVQGQTQKQTQPQVQDEQALQPQVQQQQQQQQQQQQQDTAIQAQVISPSSSTTPTPTSASSEPPANILPPQMEKIIVEIKQKKEILRRLDEELSYVRHSNIDLAEKERQSRERMLLRQKDQKQLLDNYNEHIKSRRATDDDARTVHKKLKELKAMIKQLSVEVSKQAEPVIATKAISSFWINLHEAILKLGDPLPQKRIEMLTEKFLMDVLVQSMNYNAFTGLRISQPYTQLQMWFEHYDPSFCTRLRQEIAKVVVSGNVPGSDIQQEIQKLNKRMYTSLYTSLLKAFPFIEQHDQKEKDSTKQYASMLKAMVEHASHIGYAMRGQEVEIAAAAVGEGSEPFDPKTMVDEDGQTSGTIQFCVCPPFIMYGARVEILEKARVLCSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N5Y1</accession>
    <name>A0A1C7N5Y1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Proton-coupled amino acid transporter 4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">slc36a4</name>
        <name evidence="10" type="ORF">A0J61_07904</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the amino acid/polyamine transporter 2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000564">
        <property type="protein sequence ID" value="OBZ84046.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N5Y1"/>
    <dbReference type="STRING" id="101091.A0A1C7N5Y1"/>
    <dbReference type="InParanoid" id="A0A1C7N5Y1"/>
    <dbReference type="OrthoDB" id="40134at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005774">
        <property type="term" value="C:vacuolar membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015179">
        <property type="term" value="F:L-amino acid transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1740.10">
        <property type="entry name" value="Amino acid/polyamine transporter I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013057">
        <property type="entry name" value="AA_transpt_TM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22950">
        <property type="entry name" value="AMINO ACID TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22950:SF692">
        <property type="entry name" value="TRANSMEMBRANE AMINO ACID TRANSPORTER FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01490">
        <property type="entry name" value="Aa_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0029">Amino-acid transport</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="52"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="78"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="123"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="164"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="189"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="224"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="263"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="298"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="344"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="371"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="408"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="domain" description="Amino acid transporter transmembrane" evidence="9">
        <location>
            <begin position="46"/>
            <end position="427"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008066"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OBZ84046.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="439" mass="47831" checksum="EBDD9BF86576328E" modified="2016-11-30" version="1">MSVPEKQDALQSSYQKDMNAHDMTASEHEIISEKEPSIGPADRLEGSSSVMAYLNVVCAVAGSGIVGLPLALKQGGWIGLLILFLSWSMSIFTAILLIKCLYAGSKQRLSTYMEVATEAFGKIGGYITYFFNAWILLGGPVLYMLLSGQNINQLCKGTVAEIGVVPWTIISCVVVGIPFIWLKTMKEVAVVSIFGMISILMVVFVVLIMSIIDKPNQVDVHHDPVIWSMFPISLSTIAFSFGGNVVYPHIESSMKKPRDWSKVALAGLSTCAALYLIIAVCGYAVYGDRVENPIYNSLPAGAGQIIACVVITIHVLTSAPVYTTSFSLDIEEMWGITVERFGKLGEFLIRATIRIIIMAVIGVIACTVPHFSILMSLIGAFGQCSLIFVLPIVFYLKLTGFRNKSILFLFWCFLTVLLGIVGLIFGSIDSIRELVAAFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N5Z9</accession>
    <name>A0A1C7N5Z9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Negative regulator of sexual conjugation and meiosis</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">ran1_5</name>
        <name evidence="7" type="ORF">A0J61_07517</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the protein kinase superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000511">
        <property type="protein sequence ID" value="OBZ84431.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N5Z9"/>
    <dbReference type="STRING" id="101091.A0A1C7N5Z9"/>
    <dbReference type="InParanoid" id="A0A1C7N5Z9"/>
    <dbReference type="OrthoDB" id="541276at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000042">
        <property type="entry name" value="Aurora kinase A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24345">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE PLK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3 4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="1 3 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="6">
        <location>
            <begin position="24"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="350"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="53"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OBZ84431.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="384" mass="43553" checksum="E60601FE8A2D6934" modified="2016-11-30" version="1">MTAQDTYWSQLSTSMVDKIIGDEFQLLESLGHGAYGCLFLGQSTQDNSYVAVKILPKSGLDLQQLQLQQLEIDIQSSLQHPNLLALHRVIQDTEFIYMVMELCDQGDLFDFVIRDQDINPIREEHVVKKLFSQILDGVESMHATGVYHRDIKLENVLLKCEDEEDEDELTCKVADFGLATRERYSMEFGCGSTSYLAPEHFFDEDKQELVPYDAAASDTWSLGILLLALMFGRNPWQEASTADSAYVEFKRNPTMLKQQLFPELSSGAYQLLVSVLASDGADRLSIVEMKEQFLALDHLYETQQKESPLTIPTITSKHTDANSFDSAFFSGGNGSSWSDMVEEDEELARKSDYDTCTSPEASHYDDDEDTEMFVHNGEKESWWL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N6B0</accession>
    <name>A0A1C7N6B0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_07314</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000486">
        <property type="protein sequence ID" value="OBZ84640.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N6B0"/>
    <dbReference type="InParanoid" id="A0A1C7N6B0"/>
    <dbReference type="OrthoDB" id="2255243at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ84640.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="143" mass="16083" checksum="45CF4B0D40253F8F" modified="2016-11-30" version="1">MTSDGNEDPLIFHHDMLEWSSQHATMMDYPTPPIVPNTTTNPAMPPPPPILEPGKQYHPEWGVMKDQEFHPLTLKHQRDLESLYSAGSAITDFYFWQANLGGYCMADMVQGMIVSSEGPFVLERKIVEGAPHPGRRKKKHGLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-06-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N6L5</accession>
    <name>A0A1C7N6L5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_07179</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000471">
        <property type="protein sequence ID" value="OBZ84773.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N6L5"/>
    <dbReference type="InParanoid" id="A0A1C7N6L5"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ84773.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="216" mass="25462" checksum="6B07824B52D29BF2" modified="2016-11-30" version="1">MYTGAKELRLYVQKNTRPTLNEFVATHSSLIDGSQHTLKELINLWKTRFSNAVKKYKPALRVDQLIIIDYTVWNQFKTEAVEESRSLLFQWYHLLQEKSDFLDTFLNQNSEQIELIRNNTEDNVQVFLQKLSISLFDRFDSLTSVELNVLKMSLSYIVDIIDNDMLAVYKRFIPQQYFQLWQEDEVEISVEAAEEVIITSVTDPLDYLLRLQQCCS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N6Y1</accession>
    <name>A0A1C7N6Y1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">UV excision repair protein RAD23</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">rhp23</name>
        <name evidence="9" type="ORF">A0J61_07130</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Multiubiquitin chain receptor involved in modulation of proteasomal degradation. Involved in nucleotide excision repair.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Nucleus</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the RAD23 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000465">
        <property type="protein sequence ID" value="OBZ84821.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N6Y1"/>
    <dbReference type="FunCoup" id="A0A1C7N6Y1">
        <property type="interactions" value="688"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N6Y1"/>
    <dbReference type="InParanoid" id="A0A1C7N6Y1"/>
    <dbReference type="OrthoDB" id="419317at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005654">
        <property type="term" value="C:nucleoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003684">
        <property type="term" value="F:damaged DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031593">
        <property type="term" value="F:polyubiquitin modification-dependent protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070628">
        <property type="term" value="F:proteasome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043130">
        <property type="term" value="F:ubiquitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006289">
        <property type="term" value="P:nucleotide-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043161">
        <property type="term" value="P:proteasome-mediated ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd14280">
        <property type="entry name" value="UBA1_Rad23_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd14281">
        <property type="entry name" value="UBA2_Rad23_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01805">
        <property type="entry name" value="Ubl_Rad23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.20.90:FF:000254">
        <property type="entry name" value="UV excision repair protein Rad23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.10:FF:000002">
        <property type="entry name" value="UV excision repair protein RAD23 homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.10:FF:000003">
        <property type="entry name" value="UV excision repair protein RAD23 homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.10">
        <property type="entry name" value="DNA helicase RuvA subunit, C-terminal domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.540">
        <property type="entry name" value="XPC-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004806">
        <property type="entry name" value="Rad23"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006636">
        <property type="entry name" value="STI1_HS-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015940">
        <property type="entry name" value="UBA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009060">
        <property type="entry name" value="UBA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000626">
        <property type="entry name" value="Ubiquitin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015360">
        <property type="entry name" value="XPC-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036353">
        <property type="entry name" value="XPC-bd_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00601">
        <property type="entry name" value="rad23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10621">
        <property type="entry name" value="UV EXCISION REPAIR PROTEIN RAD23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10621:SF0">
        <property type="entry name" value="UV EXCISION REPAIR PROTEIN RAD23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00627">
        <property type="entry name" value="UBA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00240">
        <property type="entry name" value="ubiquitin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09280">
        <property type="entry name" value="XPC-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01839">
        <property type="entry name" value="RAD23PROTEIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00727">
        <property type="entry name" value="STI1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00165">
        <property type="entry name" value="UBA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00213">
        <property type="entry name" value="UBQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46934">
        <property type="entry name" value="UBA-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101238">
        <property type="entry name" value="XPC-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50030">
        <property type="entry name" value="UBA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50053">
        <property type="entry name" value="UBIQUITIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 5" id="KW-0227">DNA damage</keyword>
    <keyword evidence="3 5" id="KW-0234">DNA repair</keyword>
    <keyword evidence="4 5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Ubiquitin-like" evidence="8">
        <location>
            <begin position="4"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="domain" description="UBA" evidence="7">
        <location>
            <begin position="145"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="domain" description="UBA" evidence="7">
        <location>
            <begin position="340"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="77"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="194"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="77"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="195"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="244"/>
            <end position="259"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU367049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50030"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OBZ84821.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="387" mass="42596" checksum="D634F422776DA81C" modified="2016-11-30" version="1">MAPLKLTFKTLQQKQFVLDVDSSDTIMSVKGKIEETQGYAIAQQKLIYSGKILQDDKMLGEYDIKEAGFVVVMVSKPKATSSKPSTPAATSTPKEVSAPTTETTAAAPAPVTETTTTPATETTPTQATSTEPTSTDNNSQLVTGSQLESVVQNMMEMGFEREQCVRALRASFNNPDRAVEYLFNGIPQHVLDEMNAQQQQQQQAEQPNEQQQQQQQQQQQQQQQQQQQTPSVTSPDAAPLNLFAAAAQQAQQQQTQQQQPGDQSDFANLRNTPHFQQIRQLVQSNPALLQPLLQQLGQSNPEILRSINADPSGFLQALLEGADDEEGGNAPGGSSMIQVTQEEKEAIDRLAALGFERNVVIEAYFACEKNEELAANYLFEHGYDDFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N7R6</accession>
    <name>A0A1C7N7R6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Mitochondrial import inner membrane translocase subunit TIM50</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_06757</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Component of the TIM23 complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the TIM50 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000423">
        <property type="protein sequence ID" value="OBZ85195.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N7R6"/>
    <dbReference type="STRING" id="101091.A0A1C7N7R6"/>
    <dbReference type="InParanoid" id="A0A1C7N7R6"/>
    <dbReference type="OrthoDB" id="1711508at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005744">
        <property type="term" value="C:TIM23 mitochondrial import inner membrane translocase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004274">
        <property type="entry name" value="FCP1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050365">
        <property type="entry name" value="TIM50"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12210">
        <property type="entry name" value="DULLARD PROTEIN PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03031">
        <property type="entry name" value="NIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00577">
        <property type="entry name" value="CPDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01228">
        <property type="entry name" value="COF_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50969">
        <property type="entry name" value="FCP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="1" id="KW-0653">Protein transport</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="1" id="KW-0811">Translocation</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="domain" description="FCP1 homology" evidence="2">
        <location>
            <begin position="24"/>
            <end position="182"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU365079"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50969"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ85195.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="246" mass="29016" checksum="ADF75CACCD671E56" modified="2016-11-30" version="1">MRRILKPSASYLDLVSKQSVKLKDPTRQQLLILDLNGTLVSRIGKRSMYARPYSREFLDYVFDNFNVMLWSSAQPHSVRNMSRLFSTHTKKLVAIWNRESFGLSKEDYYRKCLTIKDLDKVWEYFDGQYDATNTILIDDSPEKAQLQPYNCLHPNEFDHTSKHFTLNGESELLQLIDYLKLLQYQSNVANYIKNHPYQYQSDDTTKHTFMVAHYVFSDPHNRPVRWKDLDPKAKEEITSNMSKLSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N7X7</accession>
    <name>A0A1C7N7X7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">RING-type E3 ubiquitin transferase</fullName>
            <ecNumber evidence="5">2.3.2.27</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="19" type="primary">sip3</name>
        <name evidence="19" type="ORF">A0J61_06791</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="19 20" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19 20">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.</text>
            <dbReference type="EC" id="2.3.2.27"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Endoplasmic reticulum membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the HRD1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="19">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.27" evidence="5"/>
    <dbReference type="EMBL" id="LUGH01000427">
        <property type="protein sequence ID" value="OBZ85157.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N7X7"/>
    <dbReference type="FunCoup" id="A0A1C7N7X7">
        <property type="interactions" value="582"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N7X7"/>
    <dbReference type="InParanoid" id="A0A1C7N7X7"/>
    <dbReference type="OrthoDB" id="7759664at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036503">
        <property type="term" value="P:ERAD pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043161">
        <property type="term" value="P:proteasome-mediated ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd16479">
        <property type="entry name" value="RING-H2_synoviolin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050731">
        <property type="entry name" value="HRD1_E3_ubiq-ligases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057992">
        <property type="entry name" value="TPR_SYVN1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058051">
        <property type="entry name" value="Znf_RING_synoviolin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22763:SF184">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE SYNOVIOLIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22763">
        <property type="entry name" value="RING ZINC FINGER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25563">
        <property type="entry name" value="TPR_SYVN1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13639">
        <property type="entry name" value="zf-RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="14 17" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <keyword evidence="7 17" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="13 17" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="10" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="12" id="KW-0862">Zinc</keyword>
    <keyword evidence="9 15" id="KW-0863">Zinc-finger</keyword>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="44"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="100"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="140"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="169"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="210"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="domain" description="RING-type" evidence="18">
        <location>
            <begin position="291"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="365"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="505"/>
            <end position="559"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="16">
        <location>
            <begin position="365"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="16">
        <location>
            <begin position="411"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="16">
        <location>
            <begin position="515"/>
            <end position="529"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="16">
        <location>
            <begin position="531"/>
            <end position="542"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="OBZ85157.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="559" mass="65059" checksum="218CB84445F6127C" modified="2016-11-30" version="1">MRLAVFGGVSSILATGVILSAMYQRSNFYAACIYLYKSSACMMILLNMGLILSVLFGKLLQAIFFGRLRAIEVEHLYERAWYAVTETCLAMTIFREEFDLQFIVIFTTLLFLKIFHWLCQDRVEFMEQTPTNRLAFHVRIANLLTLLLIIDVLLATNAIQVTIVKGPTMMIMFGFEYTILICCIVSTIGKYILNIIDMQSEQTWEGKSMYVFYLDLMTDFFKLITYVLFFLYICLNYQFPIHIIRDVYMTFRSFIQKCKDLYRYRRATRNMNELYPDATSEDFSRSNDTTCIICREEMQPTDPPSLEEEEQLNPEVAAHREQNLDQPKKLPCGHIFHFHCLRSWLERQQTCPTCRRSVLVDNNDQQQQQQQQQPHQPQQQQPQQQQPSPFFQQPQQPNQQHTQSTLQEQQPETNPTLPLFNTSNPPAFSVLTPSNQPSPLPGLIPLVPMHQPIVNTELSEEDLRILSSTTREAIEQRFRILETAQHQIFQTMQMLTQVMSVMPNEQQDVQPEPEMSDRKKGKMPEREFAVQESSVDNNHTTGSSSNDNSDNNSKHVERE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N8B0</accession>
    <name>A0A1C7N8B0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">asparagine synthase (glutamine-hydrolyzing)</fullName>
            <ecNumber evidence="2">6.3.5.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">asn1</name>
        <name evidence="13" type="ORF">A0J61_06769</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>L-aspartate + L-glutamine + ATP + H2O = L-asparagine + L-glutamate + AMP + diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:12228"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:29991"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58048"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.3.5.4"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Amino-acid biosynthesis; L-asparagine biosynthesis; L-asparagine from L-aspartate (L-Gln route): step 1/1.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.5.4" evidence="2"/>
    <dbReference type="EMBL" id="LUGH01000424">
        <property type="protein sequence ID" value="OBZ85188.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N8B0"/>
    <dbReference type="FunCoup" id="A0A1C7N8B0">
        <property type="interactions" value="522"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N8B0"/>
    <dbReference type="InParanoid" id="A0A1C7N8B0"/>
    <dbReference type="OrthoDB" id="409189at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004066">
        <property type="term" value="F:asparagine synthase (glutamine-hydrolyzing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070981">
        <property type="term" value="P:L-asparagine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd01991">
        <property type="entry name" value="Asn_synthase_B_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00712">
        <property type="entry name" value="AsnB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.620:FF:000031">
        <property type="entry name" value="Asparagine synthase B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.10">
        <property type="entry name" value="Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006426">
        <property type="entry name" value="Asn_synth_AEB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001962">
        <property type="entry name" value="Asn_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050795">
        <property type="entry name" value="Asn_Synthetase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033738">
        <property type="entry name" value="AsnB_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017932">
        <property type="entry name" value="GATase_2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01536">
        <property type="entry name" value="asn_synth_AEB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006949">
        <property type="entry name" value="PRK09431.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11772">
        <property type="entry name" value="ASPARAGINE SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11772:SF2">
        <property type="entry name" value="ASPARAGINE SYNTHETASE [GLUTAMINE-HYDROLYZING]"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00733">
        <property type="entry name" value="Asn_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13537">
        <property type="entry name" value="GATase_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001589">
        <property type="entry name" value="Asn_synthetase_glu-h"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52402">
        <property type="entry name" value="Adenine nucleotide alpha hydrolases-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="N-terminal nucleophile aminohydrolases (Ntn hydrolases)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51278">
        <property type="entry name" value="GATASE_TYPE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="7" id="KW-0061">Asparagine biosynthesis</keyword>
    <keyword evidence="6 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="3" id="KW-0436">Ligase</keyword>
    <keyword evidence="5 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glutamine amidotransferase type-2" evidence="12">
        <location>
            <begin position="1"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="72"/>
        </location>
        <ligand>
            <name>L-glutamine</name>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="208"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="256"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="330"/>
            <end position="331"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="site" description="Important for beta-aspartyl-AMP intermediate formation" evidence="11">
        <location>
            <position position="332"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="13">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022888"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00048741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR001589-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR001589-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="OBZ85188.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="536" mass="60511" checksum="3DA5727F5C1DB7CB" modified="2016-11-30" version="1" fragment="single">IRHRGPDWSGCHVVKNNIFCHERLAIVGVESGAQPLVSEDGNYVLCVNGEIYNHKHLRKQLKKPHQFKTNSDCEVIMHMYDEMGTDLVNHLDGMFSFVLLDVKHNRIIAARDPIGITTLYYGWNSKMPEAVYFSSELKALNEECDKILAFPPGHLYDSETKETTRWFNPTWWDEHKIPTNPADLKALRESLEKAVHKRLMAEVPYGVLLSGGLDSSLIASIAVREAQKIANGTATEDDQFDESGPKSWPGVHSFSIGLPGSPDLLAAREVAKFLGTIHHELTFTIQEALDAVSDVIYHLETYDVTTIRASTPMYLLSRKIKALGVKMVLSGEGSDEVFGGYLYFHQAPDAAAFHTECVTRVKNLHTADCLRANKSTMAWGLEARVPFLDKEFLEVAMNVTPEEKLHKKDQGRAEKYIIRKAFDTSDDPEAKPYLPDNILWRQKEQFSDGVGYSWIDTLKAVSENKVSAEELAQAGSRWSKDTPDTKEAYMYRVMFEQWFPQPACTASVVRWIPRADWGCPSDPSGRAQKNHDQAYD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N8D3</accession>
    <name>A0A1C7N8D3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Cytochrome c oxidase polypeptide 5, mitochondrial</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">cox5</name>
        <name evidence="12" type="ORF">A0J61_06558</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="2">Energy metabolism; oxidative phosphorylation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the cytochrome c oxidase IV family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000401">
        <property type="protein sequence ID" value="OBZ85390.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N8D3"/>
    <dbReference type="FunCoup" id="A0A1C7N8D3">
        <property type="interactions" value="97"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N8D3"/>
    <dbReference type="InParanoid" id="A0A1C7N8D3"/>
    <dbReference type="OrthoDB" id="186013at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045277">
        <property type="term" value="C:respiratory chain complex IV"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004129">
        <property type="term" value="F:cytochrome-c oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006123">
        <property type="term" value="P:mitochondrial electron transport, cytochrome c to oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.442.10:FF:000002">
        <property type="entry name" value="Cytochrome c oxidase subunit V"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.442.10">
        <property type="entry name" value="Cytochrome c oxidase subunit IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004203">
        <property type="entry name" value="Cyt_c_oxidase_su4_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036639">
        <property type="entry name" value="Cyt_c_oxidase_su4_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10707:SF10">
        <property type="entry name" value="CYTOCHROME C OXIDASE SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10707">
        <property type="entry name" value="CYTOCHROME C OXIDASE SUBUNIT IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02936">
        <property type="entry name" value="COX4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81406">
        <property type="entry name" value="Mitochondrial cytochrome c oxidase subunit IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="4 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="90"/>
            <end position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004673"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="OBZ85390.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="155" mass="16906" checksum="70C1FDDEE812EC51" modified="2016-11-30" version="1">MLRTAAARTNVARVLGRRNASTNVAVQNLETRWKTLSTAEQNTIAKQLEEAQKGDWKALTVDEKKAAYYIAFGAHGPREPLTKPGHGMKVFGGVVGVMVASGALFYAIRLGGQETPRTINKEWQEATNEYLKSQNSNPIFGVSSEGYKGTGYVSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N962</accession>
    <name>A0A1C7N962_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="14">Inositol phosphosphingolipids phospholipase C</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">css1_0</name>
        <name evidence="14" type="ORF">A0J61_06283</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="2">Lipid metabolism; sphingolipid metabolism.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3">Sphingolipid metabolism.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the neutral sphingomyelinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000372">
        <property type="protein sequence ID" value="OBZ85665.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N962"/>
    <dbReference type="STRING" id="101091.A0A1C7N962"/>
    <dbReference type="InParanoid" id="A0A1C7N962"/>
    <dbReference type="OrthoDB" id="387657at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004767">
        <property type="term" value="F:sphingomyelin phosphodiesterase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006665">
        <property type="term" value="P:sphingolipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.10.10">
        <property type="entry name" value="Endonuclease/exonuclease/phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036691">
        <property type="entry name" value="Endo/exonu/phosph_ase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005135">
        <property type="entry name" value="Endo/exonuclease/phosphatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038772">
        <property type="entry name" value="Sph/SMPD2-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16320:SF24">
        <property type="entry name" value="PHOSPHODIESTERASE, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16320">
        <property type="entry name" value="SPHINGOMYELINASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03372">
        <property type="entry name" value="Exo_endo_phos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56219">
        <property type="entry name" value="DNase I-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="11" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="12" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0746">Sphingolipid metabolism</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="Endonuclease/exonuclease/phosphatase" evidence="13">
        <location>
            <begin position="10"/>
            <end position="172"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004760"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00006335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF03372"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="OBZ85665.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="182" mass="20718" checksum="9EB88814C10F993C" modified="2016-11-30" version="1">MSTVDQLKVLSFNCWGLAVVSKYRELRLRAIAEALQNQDCDLITLQEVWVAKDLERIKHAVKNKLPYSRYFPSGALGSGLAIFSKFPILSHHYHRYTLNGHPLMFIHGDYYVGKGVGSIVVKHRIIGLLEVFNTHLHASYSPAHHYTAHRAAECWQLATILRNSAAMGRQIIMASFIFAFFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NB90</accession>
    <name>A0A1C7NB90_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">L-arabinitol 4-dehydrogenase</fullName>
            <ecNumber evidence="8">1.1.1.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">lad1</name>
        <name evidence="13" type="ORF">A0J61_05721</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>L-arabinitol + NAD(+) = L-xylulose + NADH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:16381"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17399"/>
            <dbReference type="ChEBI" id="CHEBI:18403"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.1.1.12"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 11">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homotetramer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the zinc-containing alcohol dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.12" evidence="8"/>
    <dbReference type="EMBL" id="LUGH01000317">
        <property type="protein sequence ID" value="OBZ86228.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NB90"/>
    <dbReference type="FunCoup" id="A0A1C7NB90">
        <property type="interactions" value="112"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NB90"/>
    <dbReference type="InParanoid" id="A0A1C7NB90"/>
    <dbReference type="OrthoDB" id="2148442at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050019">
        <property type="term" value="F:L-arabinitol 4-dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003939">
        <property type="term" value="F:L-iditol 2-dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006062">
        <property type="term" value="P:sorbitol catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05285">
        <property type="entry name" value="sorbitol_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000068">
        <property type="entry name" value="Sorbitol dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002328">
        <property type="entry name" value="ADH_Zn_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="ER"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045306">
        <property type="entry name" value="SDH-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43161:SF12">
        <property type="entry name" value="L-ARABINITOL 4-DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43161">
        <property type="entry name" value="SORBITOL DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00059">
        <property type="entry name" value="ADH_ZINC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0520">NAD</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 11" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Enoyl reductase (ER)" evidence="12">
        <location>
            <begin position="20"/>
            <end position="357"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00038954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00039783"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00049317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU361277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="OBZ86228.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="363" mass="39240" checksum="2A6256DA4A986382" modified="2016-11-30" version="1">MSLASSSEYTVPTKDTVNHGVLLKKKDDLQLVEIPVPDPPAGQVQVQVKCTGICGSDIHLWKHGEIGIFPVTQPQLLGHESAGIVTALGEGVTSLQVGDRVAIEAGVPCSFCDQCMNGRYHLCPDVIFKSTPPYDGLLARYIVHPARWLHKIPANISYEEGALLEPLSVAIAAIDRVRAKFGRSLLITGSGPIGLLVLAVAKATGVHPIAITDVQQSRLDYAKKMGATYTYKIDSSKSETETAKEIRQLFGGEGAESVLECTGIESSFRTAIMATRDAGVCCLVGVGKNDQTIPVNNFAMREVDIRGLFRYHHTYPRAIALLSSGILDIKHMVTHKFEFSDALKAFETVADRDSGALKVQITN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NBA2</accession>
    <name>A0A1C7NBA2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Peptide hydrolase</fullName>
            <ecNumber evidence="14">3.4.-.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="primary">erm1</name>
        <name evidence="17" type="ORF">A0J61_05632</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Endoplasmic reticulum membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 14">Belongs to the peptidase M28 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.-.-" evidence="14"/>
    <dbReference type="EMBL" id="LUGH01000310">
        <property type="protein sequence ID" value="OBZ86311.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NBA2"/>
    <dbReference type="FunCoup" id="A0A1C7NBA2">
        <property type="interactions" value="57"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NBA2"/>
    <dbReference type="InParanoid" id="A0A1C7NBA2"/>
    <dbReference type="OrthoDB" id="76293at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008235">
        <property type="term" value="F:metalloexopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd03875">
        <property type="entry name" value="M28_Fxna_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.630.10:FF:000008">
        <property type="entry name" value="Endoplasmic reticulum metallopeptidase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.10">
        <property type="entry name" value="Zn peptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048024">
        <property type="entry name" value="Fxna-like_M28_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045175">
        <property type="entry name" value="M28_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007484">
        <property type="entry name" value="Peptidase_M28"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12147:SF22">
        <property type="entry name" value="ENDOPLASMIC RETICULUM METALLOPEPTIDASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12147">
        <property type="entry name" value="METALLOPEPTIDASE M28 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04389">
        <property type="entry name" value="Peptidase_M28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53187">
        <property type="entry name" value="Zn-dependent exopeptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="13" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="7 14" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="12 15" id="KW-0472">Membrane</keyword>
    <keyword evidence="6 14" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="4 14" id="KW-0645">Protease</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 15" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10 15" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="9 14" id="KW-0862">Zinc</keyword>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="28"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="376"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="427"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="469"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="501"/>
            <end position="519"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="525"/>
            <end position="545"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="557"/>
            <end position="579"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="599"/>
            <end position="619"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="631"/>
            <end position="650"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M28" evidence="16">
        <location>
            <begin position="167"/>
            <end position="349"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU361240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF04389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="OBZ86311.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="905" mass="101549" checksum="E1A22A29C8E9DA37" modified="2016-11-30" version="1">MAQKTSSQKSAYGYGSQERTPSKIARSWFILIAAILSGFSIAFCLHYRLPAPTHHDGYNPVTGLSDFSESNAMDIISHLSDRIGYRIVGTIEEKQTYDYIHDVLLKYQAEAQGKVGSPKFDIWVQQGTSSHRFDIVEKMVLKAYTNVTNIVVRLSCPIHPDHPENRSCEENAVLMNSHFDTTLGSPGATDDGSGIAVMMDLVRVLSKRDWTDYKNAIVFLFNGAEESLQDASHAFITMHEVKDSIRSVINIDSCGTSGREILFQANSREMIEAYKQAPYPHGTVMANDVFRTGLILSDTDFRQFVQYGNLTGIDMAIYKNSYLYHTHLDLTNYLESGAIQHLGANTLAIVNYLAQNATLTGIVPSSEVVFFDVQGLFFIVYSWATAYTIQMATVVLVSLYFTYIVYKTHTSSPYRSIQHILLSYTKSVLSIYLSMISAMVLPITVAMVLTSGGFDRHMAWFKHEWYGALIYSPMGLIGAYGIQYLSYFVPGPEHFDMEYGTLNSLMLMFAISTALATLTGVASSYIFWLYCSILWMTSVLNEWCLRPAASKIYLPQVGTGAYVASSFVLSLLYSDYAFALVDIFVPLTGRMGVDTPVDAIVAVIFGMIIFMISLPSVAHIHRFGRHVLKKLLTLLAILQVTVLVAVYIGGGHEGRWAFPYDELHPKRLFVQQLKNLTSGEITVNIAQLDHGPYIQTVVDRLEQELGVQAEVRHTDNMNDWDCVYPFSSFMSSHRFDVEPYIHQHAQLNSSLRPIDTLSGPFPEVKVVQDHYDPHTGVRSMSLVCLSPSYTWTVIAFDGHVVDWSIQDEAPLAEASRYVVRHVSGYGNDGWTLDVSLKVPEEDRDLAERGDWKVRFEFTALEEEGFAGKGEERKVGQVGILSIVRRSLPVWISPTWLSSVVQVWYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NBI3</accession>
    <name>A0A1C7NBI3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">MICOS complex subunit MIC12</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_05459</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000295">
        <property type="protein sequence ID" value="OBZ86492.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NBI3"/>
    <dbReference type="InParanoid" id="A0A1C7NBI3"/>
    <dbReference type="OrthoDB" id="2258660at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008889601" description="MICOS complex subunit MIC12" evidence="1">
        <location>
            <begin position="17"/>
            <end position="116"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ86492.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="116" mass="13028" checksum="83E67E82B472F846" modified="2016-11-30" version="1">MPRFISLVTGLAVATAATYKLREHLVNDQDNIQSRLESAKSTLEQAVSEQTYSKPSAYLSDSQRYVSDRLVPSVKDSWNTQIMNAAHSLVKVDIGSQAKKLWDEQVYPSLKDILNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NBR9</accession>
    <name>A0A1C7NBR9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Membrane-associated progesterone-binding protein 4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">MAPR4</name>
        <name evidence="4" type="ORF">A0J61_05401</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the cytochrome b5 family. MAPR subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000290">
        <property type="protein sequence ID" value="OBZ86543.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NBR9"/>
    <dbReference type="InParanoid" id="A0A1C7NBR9"/>
    <dbReference type="OrthoDB" id="10257697at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.120.10:FF:000003">
        <property type="entry name" value="membrane-associated progesterone receptor component 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.120.10">
        <property type="entry name" value="Cytochrome b5-like heme/steroid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001199">
        <property type="entry name" value="Cyt_B5-like_heme/steroid-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036400">
        <property type="entry name" value="Cyt_B5-like_heme/steroid_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050577">
        <property type="entry name" value="MAPR/NEUFC/NENF-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10281:SF76">
        <property type="entry name" value="CALCUTTA CUP-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10281">
        <property type="entry name" value="MEMBRANE-ASSOCIATED PROGESTERONE RECEPTOR COMPONENT-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00173">
        <property type="entry name" value="Cyt-b5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01117">
        <property type="entry name" value="Cyt-b5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55856">
        <property type="entry name" value="Cytochrome b5-like heme/steroid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="domain" description="Cytochrome b5 heme-binding" evidence="3">
        <location>
            <begin position="57"/>
            <end position="154"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00038357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM01117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OBZ86543.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="177" mass="20110" checksum="9E53056446ED10C2" modified="2016-11-30" version="1">MSNKKQTSLLSQGLIGLSWLILLFFLASYLVTESWTWGYRGKWTNIHTYIPRKERIFTEQELAQYDGTDPTKPIYLAIDGDVFDVTEGGGWYGKGGSYHHFSGKDAARAYVTGCFKEHLTHDLRGLSEDQLKGVAHWKKFYQQHHTYHKIGRVLHDPLPEDAPLPKPCASSVGKKPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NCS6</accession>
    <name>A0A1C7NCS6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Zinc finger protein 865</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">CRZ1_0</name>
        <name evidence="13" type="ORF">A0J61_05128</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000269">
        <property type="protein sequence ID" value="OBZ86818.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NCS6"/>
    <dbReference type="STRING" id="101091.A0A1C7NCS6"/>
    <dbReference type="InParanoid" id="A0A1C7NCS6"/>
    <dbReference type="OrthoDB" id="8922241at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000100">
        <property type="entry name" value="Zinc finger 45-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000446">
        <property type="entry name" value="Zinc finger protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000145">
        <property type="entry name" value="Zinc finger protein 574"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.1700">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050589">
        <property type="entry name" value="Ikaros_C2H2-ZF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24404:SF114">
        <property type="entry name" value="KLUMPFUSS, ISOFORM B-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24404">
        <property type="entry name" value="ZINC FINGER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01217">
        <property type="entry name" value="PRICHEXTENSN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="10" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 9" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="12">
        <location>
            <begin position="57"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="12">
        <location>
            <begin position="85"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="12">
        <location>
            <begin position="113"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="35"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="156"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="192"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="278"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="397"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="10">
        <location>
            <begin position="344"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="38"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="156"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="250"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="312"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="11">
        <location>
            <begin position="325"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="397"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="430"/>
            <end position="441"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00068876"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="OBZ86818.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="448" mass="49202" checksum="C7F95D5250DCA209" modified="2016-11-30" version="1">MKEYLPTPVTPASEFPQFQNPNTSSFSTFSVIKPPITPNQNNTRNSQPAVPTEAKPYPCPECHQTFSRPHNLKSHLTTHSSERPFQCDVCNHHFRRHHDLKRHQKLHTGERPYVCKDCFRSFARLDALNRHRRAEGGTACSAVHLVKQEIENVSSNSNATYHTNNKPTTSNTIADTTSPIPTAISSSATLSIPASTAPTSRPVIPQLHIPHPASHLYPRDSQPPTTAVPPSATIPSAHSPPLSGPPPPSTHLLPSPSALSTLPITNNNNLTPIVYQPKSLPITPSSPPPLQQNKSPTYHPHAFHPWSPYRSGGNSVHTESTSPVPSRPTLPPLGSPPAEIGSKLERLQQENEDLKRDIDQLRAIAQKEAGALKSRVHDLEIENKVLRSLIQNPIQTTTTTTATPVPLPATGHTEDYLKRKRKNSTSPESHTSHDSNNDCGRKSPCLRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7ND79</accession>
    <name>A0A1C7ND79_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">A0J61_04893</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000250">
        <property type="protein sequence ID" value="OBZ87063.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7ND79"/>
    <dbReference type="FunCoup" id="A0A1C7ND79">
        <property type="interactions" value="22"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7ND79"/>
    <dbReference type="InParanoid" id="A0A1C7ND79"/>
    <dbReference type="OrthoDB" id="9995210at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004842">
        <property type="term" value="F:ubiquitin-protein transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0085020">
        <property type="term" value="P:protein K6-linked ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24171">
        <property type="entry name" value="ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 39-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24171:SF8">
        <property type="entry name" value="BRCA1-ASSOCIATED RING DOMAIN PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01415">
        <property type="entry name" value="ANKYRIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="40"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="75"/>
            <end position="112"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OBZ87063.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="154" mass="17070" checksum="18A46321D23EFB57" modified="2016-11-30" version="1">MDQGTTDNDLLLAACRNDQDEMLEDVLKEPEVNVNYADPLGDTALHYAARFGSLTCLEILLSQPGIEVNSRNLKEGNTPLHLAVQYEEDPEVALSMVSALLDAGADPRIKNKANSSVADYVMGRTDDMRDLIDQGLRGYDMDNDSDEEFEVIFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NDM7</accession>
    <name>A0A1C7NDM7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Endopolyphosphatase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">PPN1_0</name>
        <name evidence="8" type="ORF">A0J61_04742</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000239">
        <property type="protein sequence ID" value="OBZ87203.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NDM7"/>
    <dbReference type="FunCoup" id="A0A1C7NDM7">
        <property type="interactions" value="63"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NDM7"/>
    <dbReference type="InParanoid" id="A0A1C7NDM7"/>
    <dbReference type="OrthoDB" id="348678at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000324">
        <property type="term" value="C:fungal-type vacuole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000298">
        <property type="term" value="F:endopolyphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004309">
        <property type="term" value="F:exopolyphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008081">
        <property type="term" value="F:phosphoric diester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006798">
        <property type="term" value="P:polyphosphate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00842">
        <property type="entry name" value="MPP_ASMase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045473">
        <property type="entry name" value="ASM_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041805">
        <property type="entry name" value="ASMase/PPN1_MPP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10340:SF55">
        <property type="entry name" value="ENDOPOLYPHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10340">
        <property type="entry name" value="SPHINGOMYELIN PHOSPHODIESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19272">
        <property type="entry name" value="ASMase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="Metallo-dependent phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Sphingomyelin phosphodiesterase C-terminal" evidence="7">
        <location>
            <begin position="384"/>
            <end position="479"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF19272"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OBZ87203.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="484" mass="55888" checksum="B857F1B481E50444" modified="2016-11-30" version="1">MIDLAENQFGMSSVPYSAWHIGQQHHISAESKKQHGYFLHITDMHIDEDYLEGATSSSSCHRLSHPLQTLKKKPVLAGKYGAVGAQCDAPVILAQETLDWISDNWKDKLDFVIWTGDNAKHDWDKKEKRKRRDVYNLNQRVTDMVLDTFWDAKIPVIPSFGNNDVFPHNQIAGPEVDGDLLSFYERLWRTWIPSDQRATFRQGGYFSIQAVPGIQVITLNSMYFFNRNKAVRNCLHPQSPAAQQMVWLEGQLKKARHDKHKVYIIGHVPPSPRDYKESCLTDYLRITTDFSDVILGQFFAHMNIDHFLMYGKETATSKSLNATTLGSDDDHHLFHTTRNINAYVDWLHTMYEEIEPPREDKHGSPDEPRSPFTVVQVSPSVLPVYNPSIRIYQYEKKQKHSAKPYGTLLGYEQYFADLSKWNAPHQKGPLQYELEYSTQEAYGMEDLSAESYFQLAKAMVEPTPEGARLWATYRNHMLVKTHKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NDQ7</accession>
    <name>A0A1C7NDQ7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Amino-acid transporter arg-13</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">arg-13</name>
        <name evidence="11" type="ORF">A0J61_06430</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000388">
        <property type="protein sequence ID" value="OBZ85514.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NDQ7"/>
    <dbReference type="STRING" id="101091.A0A1C7NDQ7"/>
    <dbReference type="InParanoid" id="A0A1C7NDQ7"/>
    <dbReference type="OrthoDB" id="2139348at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031966">
        <property type="term" value="C:mitochondrial membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000064">
        <property type="term" value="F:L-ornithine transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990575">
        <property type="term" value="P:mitochondrial L-ornithine transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050567">
        <property type="entry name" value="Mitochondrial_Carrier"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45624">
        <property type="entry name" value="MITOCHONDRIAL BASIC AMINO ACIDS TRANSPORTER-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45624:SF31">
        <property type="entry name" value="MITOCHONDRIAL ORNITHINE TRANSPORTER 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 9 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 10" id="KW-0813">Transport</keyword>
    <feature type="repeat" description="Solcar" evidence="9">
        <location>
            <begin position="31"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="9">
        <location>
            <begin position="228"/>
            <end position="315"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="OBZ85514.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="317" mass="35146" checksum="6C2914AE7EE3ADD4" modified="2016-11-30" version="1">METQQVANPSALLLKPEAIALPQINEKSTIRQQLDDLAFGSIAGMIGKFVEYPFDTIKVRLQTQPLDRPYYTGPWDCFKTTLKQEGLKGLFTGMSSPLVGSMVENAALFVGYRQVQRIIRDYSASSEEKEMYRTMTEDELPSLSMNQLILAGGASGAIASFVLTPVELIKFQTHGPSGFYRGFLATLLRETGGGMFWFGAYEYTCAQFIQYRESKTGEKVFKKDLSPSELMLGGALGGMAYNLSLFPVDVIKSQMQTDEQLTTSNTKQRTFVQTARGLYQAGGYKAFYRGCGITVARSAPTSAIIFLTYELLSRHFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NE09</accession>
    <name>A0A1C7NE09_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_04614</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000229">
        <property type="protein sequence ID" value="OBZ87335.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NE09"/>
    <dbReference type="InParanoid" id="A0A1C7NE09"/>
    <dbReference type="OrthoDB" id="2276048at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="151"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ87335.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="151" mass="17491" checksum="19393496BFA5F8ED" modified="2016-11-30" version="1" fragment="single">PNTALPKAKTQPEEYGSFVIDRAGYTYQTEVSYHYAEALKTRKYIVALQEIDTYAANEKEEFSYVNSISLFERLKIKEWKMKLKKNQLHYLPFTTAPSQLYLNTFLCNTTDTILNEKRALGKKSEIGFTVDNVSTLSKFFFPANGVLSYKW</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NE30</accession>
    <name>A0A1C7NE30_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 8">cAMP-dependent protein kinase regulatory subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">pkar_1</name>
        <name evidence="11" type="ORF">A0J61_05147</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="8">Tetramer, composed of 2 regulatory (R) and 2 catalytic (C) subunits. In the presence of cAMP it dissociates into 2 active monomeric C subunits and an R dimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 8">Belongs to the cAMP-dependent kinase regulatory chain family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000270">
        <property type="protein sequence ID" value="OBZ86806.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NE30"/>
    <dbReference type="FunCoup" id="A0A1C7NE30">
        <property type="interactions" value="375"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NE30"/>
    <dbReference type="InParanoid" id="A0A1C7NE30"/>
    <dbReference type="OrthoDB" id="417078at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005952">
        <property type="term" value="C:cAMP-dependent protein kinase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030552">
        <property type="term" value="F:cAMP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004862">
        <property type="term" value="F:cAMP-dependent protein kinase inhibitor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034236">
        <property type="term" value="F:protein kinase A catalytic subunit binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033554">
        <property type="term" value="P:cellular response to stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd00038">
        <property type="entry name" value="CAP_ED"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="CDD" id="cd12098">
        <property type="entry name" value="DD_R_ScPKA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.120.10:FF:000039">
        <property type="entry name" value="cAMP-dependent protein kinase regulatory subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.120.10:FF:000006">
        <property type="entry name" value="cAMP-dependent protein kinase type I-alpha regulatory subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="entry name" value="Jelly Rolls"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050503">
        <property type="entry name" value="cAMP-dep_PK_reg_su-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012198">
        <property type="entry name" value="cAMP_dep_PK_reg_su"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003117">
        <property type="entry name" value="cAMP_dep_PK_reg_su_I/II_a/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018488">
        <property type="entry name" value="cNMP-bd_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000595">
        <property type="entry name" value="cNMP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018490">
        <property type="entry name" value="cNMP-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11635">
        <property type="entry name" value="CAMP-DEPENDENT PROTEIN KINASE REGULATORY CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11635:SF152">
        <property type="entry name" value="CAMP-DEPENDENT PROTEIN KINASE TYPE I REGULATORY SUBUNIT-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00027">
        <property type="entry name" value="cNMP_binding"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02197">
        <property type="entry name" value="RIIa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000548">
        <property type="entry name" value="PK_regulatory"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00103">
        <property type="entry name" value="CAMPKINASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00100">
        <property type="entry name" value="cNMP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00394">
        <property type="entry name" value="RIIa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51206">
        <property type="entry name" value="cAMP-binding domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00888">
        <property type="entry name" value="CNMP_BINDING_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00889">
        <property type="entry name" value="CNMP_BINDING_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50042">
        <property type="entry name" value="CNMP_BINDING_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8 9" id="KW-0114">cAMP</keyword>
    <keyword evidence="4 8 9" id="KW-0116">cAMP-binding</keyword>
    <keyword evidence="11" id="KW-0418">Kinase</keyword>
    <keyword evidence="6 8 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="11" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Cyclic nucleotide-binding" evidence="10">
        <location>
            <begin position="182"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="domain" description="Cyclic nucleotide-binding" evidence="10">
        <location>
            <begin position="304"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="251"/>
        </location>
        <ligand>
            <name>3',5'-cyclic AMP</name>
            <dbReference type="ChEBI" id="CHEBI:58165"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="260"/>
        </location>
        <ligand>
            <name>3',5'-cyclic AMP</name>
            <dbReference type="ChEBI" id="CHEBI:58165"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="374"/>
        </location>
        <ligand>
            <name>3',5'-cyclic AMP</name>
            <dbReference type="ChEBI" id="CHEBI:58165"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="383"/>
        </location>
        <ligand>
            <name>3',5'-cyclic AMP</name>
            <dbReference type="ChEBI" id="CHEBI:58165"/>
            <label>2</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005753"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00020355"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022566"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRNR" id="PIRNR000548"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR000548-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="OBZ86806.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="430" mass="48449" checksum="67459701182720C0" modified="2016-11-30" version="1">MTFEFGGEPQQQQFTFSYADEYTQLLTELHEVYCNDHPEDVLQYCANFFNKKLEEQRMSFLRGQQSGETEHHPLAENGSMFEQEPTFRANNLSHYSSDSSYDLNDEEDEYANDYEDEDDEARDDFSTAPIHLSIPTNYNRGRRTSVSAESMAPSSQGFVKKVVAKTAEQVEGIKSSIGNNFLFKNLDEEHHQDVVDAMTETPVKEGTAIIEQGGVGDFFYVVASGTFDCFITKDEETVKVTSYEAGGSFGELALMYNAPRAATIVATSDAVLWALDRLTFRTILMENTSRKRKLYESFLEEVALLKSLEPYERHKIADALESVYFNDGEHVILQGDVGDQFYIIESGSAVFYKVDANGDQQEVNQFERGAYFGELALLNDSPRAATVVAKGRLKCATLGKKAFTRLLGSVHEILKRNSENYHAIISQQQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NE83</accession>
    <name>A0A1C7NE83_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_05104</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000266">
        <property type="protein sequence ID" value="OBZ86846.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NE83"/>
    <dbReference type="STRING" id="101091.A0A1C7NE83"/>
    <dbReference type="InParanoid" id="A0A1C7NE83"/>
    <dbReference type="OrthoDB" id="2505730at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040521">
        <property type="entry name" value="KDZ"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33096:SF1">
        <property type="entry name" value="CXC1-LIKE CYSTEINE CLUSTER ASSOCIATED WITH KDZ TRANSPOSASES DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33096">
        <property type="entry name" value="CXC2 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18758">
        <property type="entry name" value="KDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ86846.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="96" mass="11217" checksum="2527FA08777A2969" modified="2016-11-30" version="1">MGAYMKQKFLYLKENDTWYAGTAFYAYAHNMACQVRYSPKYIPNFGYTDGEGCERFWSYLNGFMSMTRSMSSSNRLLVISDSVSHFTLEKMLKLPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NEM7</accession>
    <name>A0A1C7NEM7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Nucleolar protein 9</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3 4">Pumilio domain-containing protein NOP9</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">NOP9</name>
        <name evidence="7" type="ORF">A0J61_06156</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000358">
        <property type="protein sequence ID" value="OBZ85794.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NEM7"/>
    <dbReference type="FunCoup" id="A0A1C7NEM7">
        <property type="interactions" value="566"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NEM7"/>
    <dbReference type="InParanoid" id="A0A1C7NEM7"/>
    <dbReference type="OrthoDB" id="392571at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030686">
        <property type="term" value="C:90S preribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030688">
        <property type="term" value="C:preribosome, small subunit precursor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000480">
        <property type="term" value="P:endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000447">
        <property type="term" value="P:endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000472">
        <property type="term" value="P:endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000056">
        <property type="term" value="P:ribosomal small subunit export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040000">
        <property type="entry name" value="NOP9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001313">
        <property type="entry name" value="Pumilio_RNA-bd_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13102">
        <property type="entry name" value="NUCLEOLAR PROTEIN 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13102:SF0">
        <property type="entry name" value="NUCLEOLAR PROTEIN 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22493">
        <property type="entry name" value="PUF_NOP9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00025">
        <property type="entry name" value="Pumilio"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50302">
        <property type="entry name" value="PUM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="Pumilio" evidence="5">
        <location>
            <begin position="563"/>
            <end position="598"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="9"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="20"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00016427"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00030932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00031929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OBZ85794.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="662" mass="75675" checksum="28F0310ADA020BB1" modified="2016-11-30" version="1">MPRVERKGRANKKRGKKGGKKEEVEDKQQNESVNIQPEPMEVESSSSGVVFNDQHFQSAHYGEVDEEMLGYFKGVEKTLDDPPFETGEDQRLFVENVYSEVDGNEFRLSTNYSCSLILEKLLKVSDGFQLRVFMDKMSGKTVELFAHRFASHVYQTLLTLAADVVEREQTEGVTDKGAEGEGELLSMEKLILGVCEEIKPHIGGLISQQFASHDIRILLFVLAGKRIDETGDIKGKLRSKKSTQYKRENNDTFTKANVRLSPIRKVPDSFKAMFRTLTTELAINMSETEVRTLSVHKVANPVLQLLIEMQENDKEGIKAKNILIDRILWGIVTDIDSEEQNRDRDSWFETMIRDPVGSHLLEVISKHAPDAVYKKIFKTYLTNKLEKFSLHPIANFVVQHMITHVRKSKQLSQMIKELGGSFDKLIKNGKYGVIRSLVDASVKLESSQKQIVESLASALHFNTDDKREFINCCMRMWTAEQWNQASEHERLDLYKIHLQGSLIVQGIMKMEPEANAIVTNSFLSQKPDTIHRWCFSPAGSRAFEAVVASPHVNAKMKKKIMRDLSGKYAALAKDKFGSHILEKCWLSADIESKEKIAAELVKHEHELASHYLGKNALWTCKIDQYKRRHDDWVEREKGAERKREMFKDILGEALVEKKRKLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NER4</accession>
    <name>A0A1C7NER4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Spindle pole body component</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">TUBGCP2</name>
        <name evidence="9" type="ORF">A0J61_04714</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
            <location evidence="5">Cytoskeleton</location>
            <location evidence="5">Microtubule organizing center</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the TUBGCP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000236">
        <property type="protein sequence ID" value="OBZ87239.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NER4"/>
    <dbReference type="FunCoup" id="A0A1C7NER4">
        <property type="interactions" value="713"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NER4"/>
    <dbReference type="InParanoid" id="A0A1C7NER4"/>
    <dbReference type="OrthoDB" id="2192946at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000930">
        <property type="term" value="C:gamma-tubulin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000922">
        <property type="term" value="C:spindle pole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005816">
        <property type="term" value="C:spindle pole body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043015">
        <property type="term" value="F:gamma-tubulin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051011">
        <property type="term" value="F:microtubule minus-end binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031122">
        <property type="term" value="P:cytoplasmic microtubule organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051321">
        <property type="term" value="P:meiotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007020">
        <property type="term" value="P:microtubule nucleation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000278">
        <property type="term" value="P:mitotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051225">
        <property type="term" value="P:spindle assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.120.1900:FF:000011">
        <property type="entry name" value="Spindle pole body component"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1900">
        <property type="entry name" value="Gamma-tubulin complex, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007259">
        <property type="entry name" value="GCP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040457">
        <property type="entry name" value="GCP_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042241">
        <property type="entry name" value="GCP_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041470">
        <property type="entry name" value="GCP_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19302">
        <property type="entry name" value="GAMMA TUBULIN COMPLEX PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19302:SF13">
        <property type="entry name" value="GAMMA-TUBULIN COMPLEX COMPONENT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04130">
        <property type="entry name" value="GCP_C_terminal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17681">
        <property type="entry name" value="GCP_N_terminal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 5" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="3 5" id="KW-0493">Microtubule</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Gamma tubulin complex component protein N-terminal" evidence="8">
        <location>
            <begin position="110"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="domain" description="Gamma tubulin complex component C-terminal" evidence="7">
        <location>
            <begin position="493"/>
            <end position="869"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="68"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="22"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="73"/>
            <end position="86"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010337"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU363050"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF04130"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF17681"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OBZ87239.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="887" mass="102285" checksum="E414A55BDCC810CA" modified="2016-11-30" version="1">MSRINRSLTQSPAFSRTERPFRSTTIGTSSPAIDPTNTARKSLLLSENQLNKISKKLAHIRHETLNEPDLPFQATSPVSRQASPQAHPTFPTAHHAIGDFSVQIQEYAIIEDLLYVFMGITGSYIKCIYPKSLYNLTQDDDEQEDQMQDIQSEYDVMLKHQAWDSIEYTIDPTLDPSLNHLVKKILPLATYYVSIESFIDQYSRFEYGTVNHALCAGMRVFIKEYLTFVAQLEHLFQTSTQFTLQRLWFYAQDLLSSMKIMHDLCMCIRLVKQNQRTQEEEDDIEAVIEGLQAENSDEIIIPERQKGGAILNILSERLIGLSGNPKAKKIYAFLLSKASIPYFDILNRWIYHGEIRDPYNEFMVLEKRNVHKDNLKEDYNDTYWETRYTLREGVVPVFLESMKHQILLAGKFLNVVRECGVKIASPEEMQNEVLVQGLRIDSPVPTNDQHGYLPTRSEVWAAVDGARIVKNLEIAYKYANQTLLNLLLKDQQLIGRLRSLKHYFFLDQSDFLTSFLDLAKDELNQPASEIPQARLQSLMDLVLRNPSSVAAYDPFKEDIKVSMSHLRLIDQLLRIINVSGMDSANPNTNAGASAFSHLSASLLSSTHLLERSQSLPNAIGLNQSHSQPLSGYEALILDYTVTFPLSLVISRKALTKYQLLFRHILNLKHAEDLLCGVWMNQKDQLWRKRSEHSEIEQWKFRIYSLRHRMLMFVQQFTYYVTNEVLEPNWGRLEENLARITTVDQVLQYHSDFLDTCLKECMLTNSKLLRIFNKLMGSCIAFTTQAEKFTDILAMLEKEKKPDQFGVPESSLHSNSSSTLHETTNRALSKIEESFLYHMKLLIDALNFYSTQETVQFLCLVVRLDYNQFYNNSVKTRERAATMQTRTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NF64</accession>
    <name>A0A1C7NF64_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_04557</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000226">
        <property type="protein sequence ID" value="OBZ87399.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NF64"/>
    <dbReference type="InParanoid" id="A0A1C7NF64"/>
    <dbReference type="OrthoDB" id="2284969at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="6"/>
            <end position="128"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ87399.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="135" mass="15587" checksum="E442934F852140B7" modified="2016-11-30" version="1">MSKQKIDDLKNQLDLLTEDNKNLDHEIEMAQKRLSSITDEHKQKLDQVTQLPNLIEQAKEKSKELEEIKGQTETLMSAVEELEANDSLSKKEVEQVYIKRREKQDKELASIQAELDESLNRAKELEAKVANKPSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NG08</accession>
    <name>A0A1C7NG08_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Alpha-mannosidase</fullName>
            <ecNumber evidence="3">3.2.1.24</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">ams1_0</name>
        <name evidence="10" type="ORF">A0J61_04291</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Degrades free oligosaccharides in the vacuole.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Hydrolysis of terminal, non-reducing alpha-D-mannose residues in alpha-D-mannosides.</text>
            <dbReference type="EC" id="3.2.1.24"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the glycosyl hydrolase 38 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.24" evidence="3"/>
    <dbReference type="EMBL" id="LUGH01000206">
        <property type="protein sequence ID" value="OBZ87669.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NG08"/>
    <dbReference type="FunCoup" id="A0A1C7NG08">
        <property type="interactions" value="73"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NG08"/>
    <dbReference type="InParanoid" id="A0A1C7NG08"/>
    <dbReference type="OrthoDB" id="10261055at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000329">
        <property type="term" value="C:fungal-type vacuole membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004559">
        <property type="term" value="F:alpha-mannosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006013">
        <property type="term" value="P:mannose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009313">
        <property type="term" value="P:oligosaccharide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1270.50:FF:000004">
        <property type="entry name" value="alpha-mannosidase 2C1 isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.110.10:FF:000002">
        <property type="entry name" value="alpha-mannosidase 2C1 isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.70.98.30:FF:000001">
        <property type="entry name" value="alpha-mannosidase 2C1 isoform X2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.2220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.110.10">
        <property type="entry name" value="Glycoside hydrolase 38, N terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.50">
        <property type="entry name" value="Glycoside hydrolase family 38, central domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.98.30">
        <property type="entry name" value="Golgi alpha-mannosidase II, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054723">
        <property type="entry name" value="Ams1-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011013">
        <property type="entry name" value="Gal_mutarotase_sf_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041147">
        <property type="entry name" value="GH38_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011330">
        <property type="entry name" value="Glyco_hydro/deAcase_b/a-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011682">
        <property type="entry name" value="Glyco_hydro_38_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015341">
        <property type="entry name" value="Glyco_hydro_38_cen"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037094">
        <property type="entry name" value="Glyco_hydro_38_cen_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000602">
        <property type="entry name" value="Glyco_hydro_38_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027291">
        <property type="entry name" value="Glyco_hydro_38_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028995">
        <property type="entry name" value="Glyco_hydro_57/38_cen_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46017">
        <property type="entry name" value="ALPHA-MANNOSIDASE 2C1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46017:SF1">
        <property type="entry name" value="ALPHA-MANNOSIDASE 2C1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09261">
        <property type="entry name" value="Alpha-mann_mid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22907">
        <property type="entry name" value="Ams1-like_1st"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17677">
        <property type="entry name" value="Glyco_hydro38C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07748">
        <property type="entry name" value="Glyco_hydro_38C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01074">
        <property type="entry name" value="Glyco_hydro_38N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00872">
        <property type="entry name" value="Alpha-mann_mid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88688">
        <property type="entry name" value="Families 57/38 glycoside transferase middle domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74650">
        <property type="entry name" value="Galactose mutarotase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88713">
        <property type="entry name" value="Glycoside hydrolase/deacetylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glycoside hydrolase family 38 central" evidence="9">
        <location>
            <begin position="525"/>
            <end position="605"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000365"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012752"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00054985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00071615"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00872"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OBZ87669.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="1112" mass="127065" checksum="89D607547ABDBBBF" modified="2016-11-30" version="1">MYSIQPSHNIPQVLDHPKLIRSITIDRCSNFISAGANGNDVNLLSQLYRARTNSEEYISLLVYSVPDLKRIPFEEAIQQEFRPTRLGEWFGPSWSTHWFHVQIRIPTEFEGEEVLLIWNADNEAMIWNTEGVPLQGLTGGAGGDARHEFILTPNAEGGEIMQLYIEMACNGMFGAGSGLIGPPDPNRFFHLSAADLAVPNKIAWDLLYDFQVILGMAKDLPEDSLRASQALFTANSIINAFTPGDDESMARGLEIANTFLQAKNGDAQHEIFAVGHCHIDTAWLWPFDETIRKAARSWSSQINLMDRYPDYKFICSQAQQFQWVKEKYAPLWERIIEKVSLGQFLPIGGTWVEMDTNIPGGESLCRQLLLGRCSVFWLPDSFGYSSQLPQLMLLADMKYFFTQKLSWNNVNKFPLTTFWWIGLDGSKALSHMAPSETYNAQCTPEELVRSVKNHKDKVYSNTSLLVYGNGDGGGGPLASMIERLRRMKNVDGLPKTEMAMPTEFYQKIEATSKALPSWKGELYFELHRGIYTTQSFCKKLNRSCEFLLRDIEMLATFAMMNHPNTFRYPTVELQEFWKLVCLPQFHDVMSGSAIEIVYEDCLQMYTKVDVLGRQMRQDLITTLLDLEEEMQPSTAGSTSSSPMVMDEQHQYQRKSLAVINTLPWKRHAILEVDLEETQGLADTPVKQYSAFGRTGYMVASDIEASGVTCYPLQSNSLSQSVVMIQTDRQNNVVMENQWLKVTFDQSGHLIHLYDKSVERELIKEGERGNVFRIYEDIPLFWDAWDVEIYHLEKYQTIEAGSIQILEQGPLRASLLIEKKISKTSRLRQIVILTAVSRRVDFETEVDWNENRQFLKVEFAWDILTDHVYYECQYGHVKRPTHTNTSWEAAKFEVVAQKFADMSEYGYGVALLNDCKYGHSAHRNVMRLSLLRSPKAPDSNCDVGHHSFKYAIYPHEHHFLQSDVVREGYNFNSPLLTRLVSQQKTAELAQCLPQFRIENAPNVVLDTIKKAEDSNDVIIRIYEAYGGHARARLYSSRIIKQAFKCNILEDHLEDIPINSSSGAAVNRTFSTNLRVLDDDVLELQQKEQQKQMNEGILIKVKPFEIITLKLTML</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NGN0</accession>
    <name>A0A1C7NGN0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">FAR1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_04245</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000203">
        <property type="protein sequence ID" value="OBZ87706.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NGN0"/>
    <dbReference type="STRING" id="101091.A0A1C7NGN0"/>
    <dbReference type="InParanoid" id="A0A1C7NGN0"/>
    <dbReference type="OrthoDB" id="2280694at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004330">
        <property type="entry name" value="FAR1_DNA_bnd_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47718">
        <property type="entry name" value="OS01G0519700 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47718:SF13">
        <property type="entry name" value="OS09G0290500 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03101">
        <property type="entry name" value="FAR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAR1" evidence="2">
        <location>
            <begin position="174"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="92"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="105"/>
            <end position="119"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03101"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ87706.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="344" mass="38196" checksum="831836CA957CA881" modified="2016-11-30" version="1">MKAKQDPSHDDDLLSQVNSQPLTKNITDYTQQTLLDVNSQPIIHSLSNTHLAHPILGETSIKPPNPSEDLLHAAAAVVAANPPHSLLMLPGESSPLHPADNSMEPSSTNTTTTVTTDDSSPPPIMIAPIIPMDPSNPILSEFYQRFSVGRMFDSLEDLRTEAYEYGRKHNVALTTSKSDKTKIYLICKHGGQYRRNTKRPTPGTVKPRIRKSQKTGCACMIYARHCKGSFWVIRKSIGEHNHPINSNESHYAMYRTLTPEQLLDVHRLLRDHVSVSLIVKSLKSKGASNILAKDIENIQQDLKRRNVLDLPPDHPAILPEGLLASSTIDLNTITPIDTMNNTYS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-06-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NH09</accession>
    <name>A0A1C7NH09_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_05296</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000282">
        <property type="protein sequence ID" value="OBZ86654.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NH09"/>
    <dbReference type="InParanoid" id="A0A1C7NH09"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ86654.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="154" mass="17867" checksum="46318F7C7AC9A26D" modified="2016-11-30" version="1">MKQNTDVDAEVWRSIYLKTNRANEEEAAASTLFNWCQAAFKDEVFNVDLSPVRAEVSRLEEMSRSLKEEVLVLSYKLLSSFDSLTTVERCVLKLAVSYTINLNNKIFADQYKKHFSIRNVNELLLLKAPCAEKNNEDEIRKEFRYFKKVLASSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NH91</accession>
    <name>A0A1C7NH91_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Mitochondrial substrate carrier family protein S</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">mcfS_0</name>
        <name evidence="12" type="ORF">A0J61_03584</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000157">
        <property type="protein sequence ID" value="OBZ88360.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NH91"/>
    <dbReference type="STRING" id="101091.A0A1C7NH91"/>
    <dbReference type="InParanoid" id="A0A1C7NH91"/>
    <dbReference type="OrthoDB" id="14252at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031966">
        <property type="term" value="C:mitochondrial membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000064">
        <property type="term" value="F:L-ornithine transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990575">
        <property type="term" value="P:mitochondrial L-ornithine transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050567">
        <property type="entry name" value="Mitochondrial_Carrier"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45624">
        <property type="entry name" value="MITOCHONDRIAL BASIC AMINO ACIDS TRANSPORTER-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45624:SF45">
        <property type="entry name" value="MITOCHONDRIAL CARRIER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 9 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 10" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="59"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="9">
        <location>
            <begin position="4"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="9">
        <location>
            <begin position="97"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="9">
        <location>
            <begin position="203"/>
            <end position="286"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="OBZ88360.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="287" mass="31176" checksum="70BE768E8C9985C1" modified="2016-11-30" version="1">MSNKSATADFIAGNFGGMAQVIVGQPLDTIKVRLQLDEGKFKGAWDCTVQTVRKEGFLALYKGMASPLIGIGAVNALLFAANSSIKSRLQKRPDELLSLDKIAIAGAGAGLINSILASPVELLKIKMQAQFGSRAAHDGKRFFSGPFDCARYLIQRDGMAHGLFRGLWATIVREIPAYAGFYSGFEVTKRYLTNNNQMEASVMQLMTSGAAGGVSYWVCCYPLDVVKSIVQNQEKPPRGLYVTSLLRKVYSRDGLAGLYRGFTTSVLRSIPAAGATFTAYELCIRLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NIK5</accession>
    <name>A0A1C7NIK5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_03130</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000129">
        <property type="protein sequence ID" value="OBZ88820.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NIK5"/>
    <dbReference type="InParanoid" id="A0A1C7NIK5"/>
    <dbReference type="OrthoDB" id="2282896at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12937">
        <property type="entry name" value="F-box-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="1">
        <location>
            <begin position="4"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12937"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ88820.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="600" mass="69740" checksum="13EF8E20201ED867" modified="2016-11-30" version="1">MAKWNNLPVEILEAVLKGSSKTDVLQCQLTCRSWEKSCIKIAYKQVNLFSPSRIDAFVRTIRTSTKMHGVYVTDLFLGNHFGTTMKDWDPLNQFNMLVKFCPNVEVILLMPPCIAFYQQVMRERFDGNWKKLRAINSPNKPEELEYYNAIIMTMQEKVTFITIGDQTVYGPDKSQPELYNKMLSNLENFNNLKQLNIVYHTNKGITQYDSIIDACSTLNEINIVLYPLTESVDLGEDDYQEIQPNTNITKLNIKQVIHSERTIGYIMEKFTKAEILHINDKYENVPLLDLVVQAPTYSGDFLDRFCTYLKARKFIRADNLFAQNMDEVVHYLTTHLCDFELRIPLTIHDFSDGLAFTSISLNILNQFRFISLNCVTGDTSLPFLNVLDQGGRDLRKLLITNEGVSYPDRVRLQRDFNELVTGAYLDRLFEACVNLKHLTLEKMVLIYCREQAAINRSIRHLLLKDCSIYGPIFYQLSVRLPELRILTVENWKNTNPDGRKKADRRLNFFFDMPYTAFDYLCLKCDDSPEKEVHPLFYVKLSTIEGEFYFKGSSYTLDFISAAVFRTQVSSTKTLTIQIRCKCLRRLQLSGWGMNHFYRIP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NIN6</accession>
    <name>A0A1C7NIN6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Tyrosine specific protein phosphatases domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_02949</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000119">
        <property type="protein sequence ID" value="OBZ88992.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NIN6"/>
    <dbReference type="STRING" id="101091.A0A1C7NIN6"/>
    <dbReference type="InParanoid" id="A0A1C7NIN6"/>
    <dbReference type="OrthoDB" id="9988524at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004721">
        <property type="term" value="F:phosphoprotein phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.190.10">
        <property type="entry name" value="Protein tyrosine phosphatase superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022742">
        <property type="entry name" value="Hydrolase_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029021">
        <property type="entry name" value="Prot-tyrosine_phosphatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026893">
        <property type="entry name" value="Tyr/Ser_Pase_IphP-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016130">
        <property type="entry name" value="Tyr_Pase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000387">
        <property type="entry name" value="Tyr_Pase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42886:SF53">
        <property type="entry name" value="ALPHA_BETA-HYDROLASES SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42886">
        <property type="entry name" value="RE40534P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12146">
        <property type="entry name" value="Hydrolase_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13350">
        <property type="entry name" value="Y_phosphatase3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52799">
        <property type="entry name" value="(Phosphotyrosine protein) phosphatases II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00383">
        <property type="entry name" value="TYR_PHOSPHATASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50056">
        <property type="entry name" value="TYR_PHOSPHATASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tyrosine specific protein phosphatases" evidence="1">
        <location>
            <begin position="396"/>
            <end position="432"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ88992.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="537" mass="61538" checksum="4D2F8FD62915D111" modified="2016-11-30" version="1">MSKITITNEHNESIVGILEEKHTPLPRLALIVHGVLGHKDYLFQRLLAQELPISSFRFDLRGNGESTGSPGFANMLEDTEDIHTVAAYFEAKGYEIYAVIGHSRGAIASFKYAATCEKPVPIMVNISGRFKMNDNQLNTSRPEIGQALKEHGYFDWHVKQRDRIVTIKVTQQEVDKFYNWSNEHVSRIPLSTCVLTCHGLKDNIVPPYNAAMFANRVPNHTLTLIPEADHNFKGRFEIVTKEVVDFVTQHQLNHYQKAIRMGQQAGLVIPRWIDIEGVRNFRDIGGWPVQNGSGYIRERIVFRSGNLAKITDQGRLRLRMLNVKAVFDFRLDHEVERDGFLTNTPEIVRIECNLYKEVVKTNEEYFRQLKVFLDGEKGFAEGYKVILDSGKKLIGEVFRYMIKELSIYHRSSIIIHCTAGKDRTGVFVMLLLGLCGVDDEIIAREYEMTNLGYFDFEKDLDKRSRQLGVSVENLRAALSASYGGMKLAIQQLKETYGSFEAYVIQQCGLSQIEVEAIRQLMIVPIRFEERQLYRPKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NIS8</accession>
    <name>A0A1C7NIS8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Mitochondrial pyruvate carrier</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">MPC2</name>
        <name evidence="10" type="ORF">A0J61_02915</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Mediates the uptake of pyruvate into mitochondria.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Mitochondrion inner membrane</location>
            <topology evidence="1 9">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the mitochondrial pyruvate carrier (MPC) (TC 2.A.105) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000117">
        <property type="protein sequence ID" value="OBZ89047.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NIS8"/>
    <dbReference type="FunCoup" id="A0A1C7NIS8">
        <property type="interactions" value="92"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NIS8"/>
    <dbReference type="InParanoid" id="A0A1C7NIS8"/>
    <dbReference type="OrthoDB" id="869189at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006850">
        <property type="term" value="P:pyruvate import into mitochondria"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005336">
        <property type="entry name" value="MPC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14154">
        <property type="entry name" value="UPF0041 BRAIN PROTEIN 44-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03650">
        <property type="entry name" value="MPC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 9" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5 9" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="10" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 9" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="83"/>
            <end position="102"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006416"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU363100"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OBZ89047.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="121" mass="13530" checksum="94B40F539A0A0351" modified="2016-11-30" version="1">MATSAASSAVQKGAFRRFMDSPAGPKTIHFWAPAMKWALVFASIGDLQRPADKLSLTQNMSLMLTGAIWSRYSMVIIPKNYSLFTVNIFVFATGAAQVARIFKYRQSEEYKAQQTLEQKQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NIT3</accession>
    <name>A0A1C7NIT3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_03032</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000124">
        <property type="protein sequence ID" value="OBZ88910.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NIT3"/>
    <dbReference type="InParanoid" id="A0A1C7NIT3"/>
    <dbReference type="OrthoDB" id="2271250at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ88910.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="93" mass="10854" checksum="7BCE5B0C3985E06B" modified="2016-11-30" version="1">MGLIDKLKTQYDLHQVNQYTKRREGQSGFEFKNKEHYKVTYKDGVYADIHMKSSMTHSPKSILTDIIRKTTPKKRRSLAVELNKTSESYSLSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NJ07</accession>
    <name>A0A1C7NJ07_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_02801</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000111">
        <property type="protein sequence ID" value="OBZ89137.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NJ07"/>
    <dbReference type="STRING" id="101091.A0A1C7NJ07"/>
    <dbReference type="InParanoid" id="A0A1C7NJ07"/>
    <dbReference type="OrthoDB" id="5599130at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="30"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="71"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="90"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ89137.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="90" mass="10483" checksum="4A018882FB8ED4B8" modified="2016-11-30" version="1" fragment="single">MPEQQNSTTPTTDQQDSAEDNTNQQGQDNKKKRTGPKRRKVTHGRPCQRCIKRSIGHLCHDEVKQPANSAQQHQQQQQQQQQQQQQQQQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NJI5</accession>
    <name>A0A1C7NJI5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">37S ribosomal protein S28, mitochondrial</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">MRPS28</name>
        <name evidence="6" type="ORF">A0J61_02669</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the universal ribosomal protein uS15 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000103">
        <property type="protein sequence ID" value="OBZ89287.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NJI5"/>
    <dbReference type="STRING" id="101091.A0A1C7NJI5"/>
    <dbReference type="InParanoid" id="A0A1C7NJI5"/>
    <dbReference type="OrthoDB" id="441444at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00353">
        <property type="entry name" value="Ribosomal_S15p_S13e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.10">
        <property type="entry name" value="S15/NS1, RNA-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01343_B">
        <property type="entry name" value="Ribosomal_uS15_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000589">
        <property type="entry name" value="Ribosomal_uS15"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005290">
        <property type="entry name" value="Ribosomal_uS15_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009068">
        <property type="entry name" value="uS15_NS1_RNA-bd_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00952">
        <property type="entry name" value="S15_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23321">
        <property type="entry name" value="RIBOSOMAL PROTEIN S15, BACTERIAL AND ORGANELLAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23321:SF26">
        <property type="entry name" value="SMALL RIBOSOMAL SUBUNIT PROTEIN US15M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00312">
        <property type="entry name" value="Ribosomal_S15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01387">
        <property type="entry name" value="Ribosomal_S15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47060">
        <property type="entry name" value="S15/NS1 RNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00362">
        <property type="entry name" value="RIBOSOMAL_S15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 6" id="KW-0689">Ribosomal protein</keyword>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="115"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OBZ89287.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="241" mass="27382" checksum="0D24F312737770BF" modified="2016-11-30" version="1">MLGRSSVVNTKRIAFAVVSKQPFHSSAAALAKKHPKQVKKENLAKRAAKLAEFERTKPSFIVSKPTPFFNTLHTPASAYQQNSTGYQHFLTETDQKFLFEETPKKSVESSHMAAVDGLDEALKQEKTKVETLQKLLSLQNANAKAVQIFNIHQAIDWFKQKEGDTGSPEVQAAILTVRIHNLNSHLNQHHKDRHNYKQLRNMVHQRAKILKYLKSKNADRYFTCLEKLGLEPRAVEGEITL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NJM6</accession>
    <name>A0A1C7NJM6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Elongation factor Ts, mitochondrial</fullName>
            <shortName evidence="4">EF-Ts</shortName>
            <shortName evidence="4">EF-TsMt</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4 6" type="primary">TSF1</name>
        <name evidence="6" type="ORF">A0J61_02621</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the EF-Ts family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000101">
        <property type="protein sequence ID" value="OBZ89331.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NJM6"/>
    <dbReference type="FunCoup" id="A0A1C7NJM6">
        <property type="interactions" value="350"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NJM6"/>
    <dbReference type="InParanoid" id="A0A1C7NJM6"/>
    <dbReference type="OrthoDB" id="277235at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070125">
        <property type="term" value="P:mitochondrial translational elongation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd14275">
        <property type="entry name" value="UBA_EF-Ts"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.10">
        <property type="entry name" value="DNA helicase RuvA subunit, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.479.20">
        <property type="entry name" value="Elongation factor Ts, dimerisation domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00050">
        <property type="entry name" value="EF_Ts"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036402">
        <property type="entry name" value="EF-Ts_dimer_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001816">
        <property type="entry name" value="Transl_elong_EFTs/EF1B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014039">
        <property type="entry name" value="Transl_elong_EFTs/EF1B_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018101">
        <property type="entry name" value="Transl_elong_Ts_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009060">
        <property type="entry name" value="UBA-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11741">
        <property type="entry name" value="ELONGATION FACTOR TS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11741:SF0">
        <property type="entry name" value="ELONGATION FACTOR TS, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00889">
        <property type="entry name" value="EF_TS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54713">
        <property type="entry name" value="Elongation factor Ts (EF-Ts), dimerisation domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46934">
        <property type="entry name" value="UBA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01127">
        <property type="entry name" value="EF_TS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4 6" id="KW-0251">Elongation factor</keyword>
    <keyword evidence="4" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="3 4" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Translation elongation factor EFTs/EF1B dimerisation" evidence="5">
        <location>
            <begin position="104"/>
            <end position="278"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022768"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00889"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OBZ89331.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="337" mass="36707" checksum="2084676293A65789" modified="2016-11-30" version="1">MNKVGMIRNFSQALSRCYSTEVKPNMKLLKDLRKETEVSMSKAKEALVKNNNDYAKALAWLSEDAAVSGAKKAQKVAGRTAGEGLITTASVQVPVLNGFKSKSTIIELNCETDFVSRNDVFKNLASRIAATSLLIHDHNHANSQRLIQSIAVDDLLNAPLMPHPNDTELDTTEVGKTVKETIVETIGKLGENIALRRAAIVAEGISACYIHGGDANSGKMGGIAVLQPRKVVNEEEAANALTKTARQVARQVVGFNPTYLNTEDAPASEITNLAEFEEAHVLNKQKYLLNPDITLAQHVEQTVDADIVDFIRWEVGEGIEKKENDFADEVLNAARGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NK43</accession>
    <name>A0A1C7NK43_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Rho guanine nucleotide exchange factor scd1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">scd1_0</name>
        <name evidence="5" type="ORF">A0J61_04297</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000207">
        <property type="protein sequence ID" value="OBZ87654.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NK43"/>
    <dbReference type="FunCoup" id="A0A1C7NK43">
        <property type="interactions" value="80"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NK43"/>
    <dbReference type="InParanoid" id="A0A1C7NK43"/>
    <dbReference type="OrthoDB" id="1594986at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000935">
        <property type="term" value="C:division septum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043332">
        <property type="term" value="C:mating projection tip"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005085">
        <property type="term" value="F:guanyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030010">
        <property type="term" value="P:establishment of cell polarity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035556">
        <property type="term" value="P:intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031106">
        <property type="term" value="P:septin ring organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00014">
        <property type="entry name" value="CH_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd05992">
        <property type="entry name" value="PB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00160">
        <property type="entry name" value="RhoGEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.418.10">
        <property type="entry name" value="Calponin-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.900.10">
        <property type="entry name" value="Dbl homology (DH) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010481">
        <property type="entry name" value="Cdc24/Scd1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053026">
        <property type="entry name" value="CDC42_GEF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036872">
        <property type="entry name" value="CH_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035899">
        <property type="entry name" value="DBL_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000219">
        <property type="entry name" value="DH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001331">
        <property type="entry name" value="GDS_CDC24_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053793">
        <property type="entry name" value="PB1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000270">
        <property type="entry name" value="PB1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47339">
        <property type="entry name" value="CELL DIVISION CONTROL PROTEIN 24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47339:SF1">
        <property type="entry name" value="CELL DIVISION CONTROL PROTEIN 24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06395">
        <property type="entry name" value="CDC24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00564">
        <property type="entry name" value="PB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15411">
        <property type="entry name" value="PH_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00621">
        <property type="entry name" value="RhoGEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00666">
        <property type="entry name" value="PB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00325">
        <property type="entry name" value="RhoGEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54277">
        <property type="entry name" value="CAD &amp; PB1 domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47576">
        <property type="entry name" value="Calponin-homology domain, CH-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48065">
        <property type="entry name" value="DBL homology domain (DH-domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00741">
        <property type="entry name" value="DH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50010">
        <property type="entry name" value="DH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51745">
        <property type="entry name" value="PB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DH" evidence="3">
        <location>
            <begin position="202"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="domain" description="PB1" evidence="4">
        <location>
            <begin position="775"/>
            <end position="859"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="575"/>
            <end position="638"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="666"/>
            <end position="705"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="359"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="580"/>
            <end position="592"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="626"/>
            <end position="638"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="666"/>
            <end position="680"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="689"/>
            <end position="702"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51745"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OBZ87654.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="859" mass="98037" checksum="7AE6349DF7C51898" modified="2016-11-30" version="1">MAVNRRNPSAMPDLAPPSPSPLRPVNTAVPAMNTSPALTAANTTTGTNSLYHTCLSVLNRLTCVEGMSDYIHSETSTDPLSKLTSICRQGYPLCTLYNALNPLEPLKSKADPTLNAVNSCKANVYHFIVACKHVLLFEEDDMFTISDLYQDDTNGFVKVVNTVNKLLKLLEERGIISVQSSRRNSDNDHQKMDLSNNVPKNTRDKVVMELLETERKYVQDMEILQNYMRELQHKKIVSPDTIHYLFGNLNALVDFQRRFLIQMEEIAEKQPEEQRIGYLFLQMEEYFCVYEPYCANYYSAQDLVVQETPRLQQLNHILNPIYELPSLLIKPVQRICKYPLLLQELVRSTDSSWLYYHELQQSLESMKRVTERINETQRQCENMQSVQELKDRLNQWRRQIVDGCGNLLLQDKLIATCQAIDNSEREREVHVFCFDKALLIFKEKANNLSIKKKRQGSLVPKLIIQTSSIADVEDQFKNNNWWLQIHLQDSESDHLSIKFRNEEQVKLWSTTLIKASKKAQAASDYMLSTHFESSYSDEFGDEEDDFFDDDEEECISYRSRSNSFSQQQSIRGKLGPIQSHDMSQKQSSTGRPYNNVPGMNLSPLPRSNSNLNYQYYPVSPPPSYPSSPTSSSRTSSNSNWARTDGIYADMAPSLFDYQSTEFSQRTLLSTGRSQSQSAPCGSTRPALPVNQTRLRSQSSPNIMKNGVTVPVLSTSSSTATSQQNELKVPQVPMVRQYNHKPAPLDLSRQKSQVIRSPNTTPRLADGTILPPSPGTVRIKLNFNDGIYVIVANHEATFYEIMERVDRKIRLVANLKQNDVLRLKYQDEDGDYITINSDDDVQMAFESQLAHNTVNMFVSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NKS4</accession>
    <name>A0A1C7NKS4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative allantoinase 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">allB1</name>
        <name evidence="3" type="ORF">A0J61_02211</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000080">
        <property type="protein sequence ID" value="OBZ89743.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NKS4"/>
    <dbReference type="STRING" id="101091.A0A1C7NKS4"/>
    <dbReference type="InParanoid" id="A0A1C7NKS4"/>
    <dbReference type="OrthoDB" id="5398391at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006144">
        <property type="term" value="P:purine nucleobase metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3330.10">
        <property type="entry name" value="Oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018020">
        <property type="entry name" value="OHCU_decarboxylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036778">
        <property type="entry name" value="OHCU_decarboxylase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37987">
        <property type="entry name" value="CHROMOSOME 9, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37987:SF1">
        <property type="entry name" value="OXO-4-HYDROXY-4-CARBOXY-5-UREIDOIMIDAZOLINE DECARBOXYLASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09349">
        <property type="entry name" value="OHCU_decarbox"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF158694">
        <property type="entry name" value="UraD-Like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0659">Purine metabolism</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase" evidence="2">
        <location>
            <begin position="11"/>
            <end position="171"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022631"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF09349"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ89743.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="180" mass="20559" checksum="3292C29FE55329FC" modified="2016-11-30" version="1">MASLPVIEQLNKESSENFIKAVNVLFETAPPLAQRLLNRRPYQSYTDLIDYAEKICLGEELSQEEKLEVMNAHPRIGASKANLSVSSLKEQGYDSRTSNLSEQDEEVNAKLAHLNQVYEDKYGFKFVVFVNGRPRHQIVPIIEERIASDNREEELKTGITDMMLIARDRLKKANFDSSKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NL26</accession>
    <name>A0A1C7NL26_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Curved DNA-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">cdb4</name>
        <name evidence="3" type="ORF">A0J61_02120</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase M24 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000076">
        <property type="protein sequence ID" value="OBZ89822.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NL26"/>
    <dbReference type="FunCoup" id="A0A1C7NL26">
        <property type="interactions" value="1032"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NL26"/>
    <dbReference type="InParanoid" id="A0A1C7NL26"/>
    <dbReference type="OrthoDB" id="5876363at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01089">
        <property type="entry name" value="PA2G4-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.10:FF:000029">
        <property type="entry name" value="Proliferation-associated 2G4, a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.230.10">
        <property type="entry name" value="Creatinase/methionine aminopeptidase superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036005">
        <property type="entry name" value="Creatinase/aminopeptidase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004545">
        <property type="entry name" value="PA2G4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047113">
        <property type="entry name" value="PA2G4/ARX1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000994">
        <property type="entry name" value="Pept_M24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00495">
        <property type="entry name" value="crvDNA_42K"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10804:SF11">
        <property type="entry name" value="PROLIFERATION-ASSOCIATED PROTEIN 2G4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10804">
        <property type="entry name" value="PROTEASE FAMILY M24 METHIONYL AMINOPEPTIDASE, AMINOPEPTIDASE P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00557">
        <property type="entry name" value="Peptidase_M24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55920">
        <property type="entry name" value="Creatinase/aminopeptidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase M24" evidence="2">
        <location>
            <begin position="29"/>
            <end position="199"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007319"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ89822.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="377" mass="41164" checksum="C8CA17A0831AA6A9" modified="2016-11-30" version="1">MADTTKPVDTKKPAAEPVLDISNSDVQTKYKDAGKIADAALEKVIALCVPGAKVIDICVEGDKLINEATKAIYNKKKISKGVGFPTTISINNCVAHFSPLPSDPESETVLKEGDVAKIQLGAQFDGFCSTVASTVVVGGGAVTGTKADVIKAAETALEATIRMIRPGNKNMDITKAVDKIAEAYNVKPVEGMLSHNQLKDKTDGEKQIILNPTEAHLRDFKRVEFAENEVYAIDILISSGEGKVRPLKTRTTIYKKTGVRYQLKMAASRAVLSEIQTKAGAFPFSLRDLEDERKARMGIVEAAKHQTVLPYDVVYERDEAVVAQYLATIMVTKNGNTLLTHPKYLEVQTEKKVEDEEIAKLLATSYEPPKKEKKAKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NLK2</accession>
    <name>A0A1C7NLK2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">CCR4-NOT transcription complex subunit 11</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">cnot11</name>
        <name evidence="10" type="ORF">A0J61_01970</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the CNOT11 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000069">
        <property type="protein sequence ID" value="OBZ89987.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NLK2"/>
    <dbReference type="STRING" id="101091.A0A1C7NLK2"/>
    <dbReference type="InParanoid" id="A0A1C7NLK2"/>
    <dbReference type="OrthoDB" id="10265389at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030014">
        <property type="term" value="C:CCR4-NOT complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031047">
        <property type="term" value="P:regulatory ncRNA-mediated gene silencing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019312">
        <property type="entry name" value="CNOT11"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15975">
        <property type="entry name" value="CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15975:SF0">
        <property type="entry name" value="CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10155">
        <property type="entry name" value="CNOT11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0943">RNA-mediated gene silencing</keyword>
    <keyword evidence="8" id="KW-0804">Transcription</keyword>
    <keyword evidence="6" id="KW-0805">Transcription regulation</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008030"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00014872"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OBZ89987.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="312" mass="36300" checksum="402AA8273308724E" modified="2016-11-30" version="1">MDKEDSTFSEIYASFCLKQEQEHQDAFEAACCVFLQYEPSRKQATRLSILYILYRHYTALPIDRNPFLTFFLELVDELPQASLEHHFLFCILEQTLPNLDSLFPHTLSSTELPSVKNDSSLIDLLHQRVTRLIDDPDLVVLDPQIEQLLTEASQRTLTLSENELLSHERLIDYTHLIVPDQLPRLMDLNQFVAMEIVPLLLKSDSSYLEALVMAPISMNSIEIVHHILVNHRPLPQDFLHHYIANSIRACDRMEDSPKKDRQVKQVARFIQSLLEKKMIPMSDYVVEIQAFCVSYMKLKSVVDLFRLVSYKH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NM18</accession>
    <name>A0A1C7NM18_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">A0J61_01788</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000061">
        <property type="protein sequence ID" value="OBZ90162.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NM18"/>
    <dbReference type="FunCoup" id="A0A1C7NM18">
        <property type="interactions" value="79"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NM18"/>
    <dbReference type="InParanoid" id="A0A1C7NM18"/>
    <dbReference type="OrthoDB" id="6730379at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791:SF63">
        <property type="entry name" value="HIGH AFFINITY CYSTEINE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791">
        <property type="entry name" value="PERMEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="53"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="92"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="123"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="150"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="181"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="216"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="282"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="318"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="345"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="373"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="404"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="437"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="8">
        <location>
            <begin position="53"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OBZ90162.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="492" mass="54675" checksum="F8DF8EA228FBA032" modified="2016-11-30" version="1">MSIHKETYTDEKAASVDTNRGELSDDDVRSNHQAPFVKSEAEKRLVRKINYTLLPFVGAIVFIQFVDKSTLSISAVLGLISDTHLTGSQYSWLGSFFYLGYIAFQLPNNYLIQKIPVARYLGILLVLWGIVMACTALCTNFAQLAALRTLLGLFEAGCYPCLLIILNTVYRRSEQSAAYGFLWLSNGAGTMVGAACAYGISYINNARGIASWKWPYIIWGALTVLFGVLVFFFLPDTPNSFMFRLTEEEKEIVKERTRDNAVVRVYEVKKSHILEALREPRLWLICLSTFCNNLHTGGLVVFSTLLVNSLGFDKQNSILLQVPSGFSSALFCGIAVLIARKTGQLYLAAAVSSTISLVGVILLAVLPNSAIKLLGYFLAWAMNGTAVILLTIVSANVTGYTKKIFYNAMYMIFFTIGNFIGPLVMLETEAPIYKTGMIVYCIGNGAVILMLFFVRQIMARQNKKRLANPSNEIYDVADDLTDQQNKSLIYKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NM27</accession>
    <name>A0A1C7NM27_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">NSFL1 cofactor p47</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">NSFL1C</name>
        <name evidence="6" type="ORF">A0J61_02032</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000072">
        <property type="protein sequence ID" value="OBZ89909.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NM27"/>
    <dbReference type="FunCoup" id="A0A1C7NM27">
        <property type="interactions" value="709"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NM27"/>
    <dbReference type="InParanoid" id="A0A1C7NM27"/>
    <dbReference type="OrthoDB" id="25887at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043130">
        <property type="term" value="F:ubiquitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000045">
        <property type="term" value="P:autophagosome assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007030">
        <property type="term" value="P:Golgi organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061025">
        <property type="term" value="P:membrane fusion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051028">
        <property type="term" value="P:mRNA transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031468">
        <property type="term" value="P:nuclear membrane reassembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043161">
        <property type="term" value="P:proteasome-mediated ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd14348">
        <property type="entry name" value="UBA_p47"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01770">
        <property type="entry name" value="UBX_UBXN2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.20.90:FF:000179">
        <property type="entry name" value="Plant UBX domain-containing protein 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.210:FF:000002">
        <property type="entry name" value="UBX domain-containing protein 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.10">
        <property type="entry name" value="DNA helicase RuvA subunit, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.210">
        <property type="entry name" value="SEP domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036241">
        <property type="entry name" value="NSFL1C_SEP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012989">
        <property type="entry name" value="SEP_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005637">
        <property type="entry name" value="TAP_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009060">
        <property type="entry name" value="UBA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054109">
        <property type="entry name" value="UBA_8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001012">
        <property type="entry name" value="UBX_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23333:SF20">
        <property type="entry name" value="NSFL1 COFACTOR P47"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23333">
        <property type="entry name" value="UBX DOMAIN CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08059">
        <property type="entry name" value="SEP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22566">
        <property type="entry name" value="UBA_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00789">
        <property type="entry name" value="UBX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00553">
        <property type="entry name" value="SEP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00166">
        <property type="entry name" value="UBX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102848">
        <property type="entry name" value="NSFL1 (p97 ATPase) cofactor p47, SEP domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46934">
        <property type="entry name" value="UBA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51399">
        <property type="entry name" value="SEP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51281">
        <property type="entry name" value="TAP_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50033">
        <property type="entry name" value="UBX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="TAP-C" evidence="4">
        <location>
            <begin position="2"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="domain" description="SEP" evidence="5">
        <location>
            <begin position="197"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="domain" description="UBX" evidence="3">
        <location>
            <begin position="308"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="45"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="143"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="280"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="56"/>
            <end position="89"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51399"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OBZ89909.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="385" mass="41857" checksum="2E3A9784C13B9AED" modified="2016-11-30" version="1">MSDQQDLIQQFASLTGANELQSKFFLEANNWDLELAASQFFENGGAEVPDMTSSHVPQQQQEQLVQPAVIGSSPTTTPAKRKPAPASSSQVRTLRDLMSSNENNSASDEEHENLYAGGEKSGMIVQGPNKRGGANLVDEILKKAAEGGQSPEEAPKKSQKKSAYAGVGYRLGSEDEPSTRVQPAVDSDDEEEEELESVTRNLTFWRNGFSVDDGPLYAYADPANQEMLNSINDGRAPLSLLNVRHGQPVEVRVVKRQDEDYVAPKVPVKPFAGTGIRLGSAASYSPSPPPSSSPAATTSPVNTITVDDAQPTTNIQIRLADGSRLIARLNHTHTVADIRRFIESSHPTTRAYVLQTTFPVKELKDNDQTVKEAGLLNSVIVQRYQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NM35</accession>
    <name>A0A1C7NM35_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Putative E3 ubiquitin-protein ligase C36B7.05c</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">A0J61_02043</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000072">
        <property type="protein sequence ID" value="OBZ89919.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NM35"/>
    <dbReference type="FunCoup" id="A0A1C7NM35">
        <property type="interactions" value="40"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NM35"/>
    <dbReference type="InParanoid" id="A0A1C7NM35"/>
    <dbReference type="OrthoDB" id="10057496at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd15760">
        <property type="entry name" value="FYVE_scVPS27p_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052113">
        <property type="entry name" value="FYVE-type_Zinc_Finger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000306">
        <property type="entry name" value="Znf_FYVE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017455">
        <property type="entry name" value="Znf_FYVE-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39490">
        <property type="entry name" value="ARRESTIN DOMAIN-CONTAINING PROTEIN D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39490:SF8">
        <property type="entry name" value="ZINC FINGER FYVE DOMAIN-CONTAINING PROTEIN 21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01363">
        <property type="entry name" value="FYVE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13639">
        <property type="entry name" value="zf-RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00064">
        <property type="entry name" value="FYVE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50178">
        <property type="entry name" value="ZF_FYVE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="FYVE-type" evidence="7">
        <location>
            <begin position="68"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="domain" description="RING-type" evidence="6">
        <location>
            <begin position="222"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="31"/>
            <end position="41"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50178"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OBZ89919.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="268" mass="30925" checksum="C9FD166564AC3B15" modified="2016-11-30" version="1">MTDTQASLSEIPAEEADITETLPHGHYSPLQENVSVNQVSSESEEDVTEERTIQPVHLPRSQRVWEMDRQAPECRRCHRRFNFLVRRHHCRRCGQIVCDRCSSNRLKLPVEELVEDPMISLSQYPYLATQTQRVCDSCYREPIVDHRRRTRSTVPTDMRRTNSAQSLMIDCPVCGRTFLGMQKYQQEAHLQQCLNIGSPPVQSPRYIVYELSSDSAQIGDECPICFDEFEQGDQVSRMICLCSYHQACLASWLQRGKGCPVHYDSIQI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NMC5</accession>
    <name>A0A1C7NMC5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_01782</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000061">
        <property type="protein sequence ID" value="OBZ90168.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NMC5"/>
    <dbReference type="FunCoup" id="A0A1C7NMC5">
        <property type="interactions" value="1"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NMC5"/>
    <dbReference type="InParanoid" id="A0A1C7NMC5"/>
    <dbReference type="OrthoDB" id="2011986at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018810">
        <property type="entry name" value="UPF0662"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28086:SF1">
        <property type="entry name" value="CU(2+) SUPPRESSING AND BLEOMYCIN SENSITIVE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28086">
        <property type="entry name" value="UPF0662 PROTEIN YPL260W"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10303">
        <property type="entry name" value="DUF2408"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ90168.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="430" mass="49235" checksum="FD2CCA839938B7B9" modified="2016-11-30" version="1">MLTVPNEEIPVLESLITIRHKLSALKKDRESYPDADVVTSLYKETEKQVEKINEIRIGDVWNTASRNRLNDVLDDIMALLSLFFMSLGRNRESPAVYVQLVTVERYLDQLSHMGIYTDTILLENQGRLKDIETILFADSSGSCFVELLKHKLKICKETLSLLLSNVQDVSESLKLPRKPLHEELVELRRKLSLLAQQPNGYTAAEVDQIQEKLREYDQMKIELFRSNPKGRELIEGLLEQLHEETQDMKASTNSVSESLAPIVERLKQIKLQLERLALTHKWTLRETDLYTFHLQLQEVEKLRRDGKFTDPASDTVPEGQAVVNFLLRGCYRIMAKMLSENVPVAEALMPVHNQLSTVRRCLVEVTKWGKPDSVRDLYPYQMKLASIDNMRINGTFCDEEGNIPEGQAVCVALLNECYDILHELIALADA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NMI9</accession>
    <name>A0A1C7NMI9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Chaperone protein DnaJ</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">dnaJ_1</name>
        <name evidence="4" type="ORF">A0J61_02277</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000083">
        <property type="protein sequence ID" value="OBZ89686.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NMI9"/>
    <dbReference type="STRING" id="101091.A0A1C7NMI9"/>
    <dbReference type="InParanoid" id="A0A1C7NMI9"/>
    <dbReference type="OrthoDB" id="10250354at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051787">
        <property type="term" value="F:misfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051087">
        <property type="term" value="F:protein-folding chaperone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036503">
        <property type="term" value="P:ERAD pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018253">
        <property type="entry name" value="DnaJ_domain_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051948">
        <property type="entry name" value="Hsp70_co-chaperone_J-domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44360">
        <property type="entry name" value="DNAJ HOMOLOG SUBFAMILY B MEMBER 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44360:SF1">
        <property type="entry name" value="DNAJ HOMOLOG SUBFAMILY B MEMBER 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00625">
        <property type="entry name" value="JDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00636">
        <property type="entry name" value="DNAJ_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0143">Chaperone</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="J" evidence="3">
        <location>
            <begin position="4"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="92"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="97"/>
            <end position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OBZ89686.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="115" mass="13109" checksum="3F812C8124FB14A5" modified="2016-11-30" version="1">MLEDLYRALGLTGSASLEEIKKAYRLLAKEYHPDKNKDGAEKFKEISHAYSILTDPEKRKEYAAKQYAEAPSRQYSYSFNMHDPFANPFGFPFFTRDPPPPPPPQASNPPSKITI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NMK9</accession>
    <name>A0A1C7NMK9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">C3H1-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">A0J61_01636</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000054">
        <property type="protein sequence ID" value="OBZ90315.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NMK9"/>
    <dbReference type="STRING" id="101091.A0A1C7NMK9"/>
    <dbReference type="InParanoid" id="A0A1C7NMK9"/>
    <dbReference type="OrthoDB" id="411372at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.1190">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.1000.10">
        <property type="entry name" value="Zinc finger, CCCH-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041367">
        <property type="entry name" value="Znf-CCCH_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000571">
        <property type="entry name" value="Znf_CCCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036855">
        <property type="entry name" value="Znf_CCCH_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00642">
        <property type="entry name" value="zf-CCCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18044">
        <property type="entry name" value="zf-CCCH_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00356">
        <property type="entry name" value="ZnF_C3H1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90229">
        <property type="entry name" value="CCCH zinc finger"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50103">
        <property type="entry name" value="ZF_C3H1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C3H1-type" evidence="6">
        <location>
            <begin position="68"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="domain" description="C3H1-type" evidence="6">
        <location>
            <begin position="97"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="4">
        <location>
            <begin position="68"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="4">
        <location>
            <begin position="97"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="356"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="433"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="511"/>
            <end position="533"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="439"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="513"/>
            <end position="533"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OBZ90315.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="543" mass="59785" checksum="C78FA5C2430FBA25" modified="2016-11-30" version="1">MTDPNLLFSSDLSLNLLSKSSPSQLQPFQYKRSRTQPASAETPYPQKMTTIAANNSTTNSNSNLKPSNLSHVPCKFYKQGTCTAGANCTFSHSSDLSSESAVCKYFVKGNCKFGTKCALLHTMSPFGTTNTTAASTNKINGSNSNRLMMASTPPQPSLLAFTGRRKTTDQVTIPLSSSIHNPSHPDHRSFSNDPFGSSAPAVSLFHHHYQQLSEQQQQQNVWRNPQSPRTNMSTDDFIGLHSSPRESSDYLLGTSPFANYRLYSSVKSNNSGFFNNTTTDYRRQSSFANNTPTTAATVGSYSTIFDDNHTSSFFSHQQSQQQQEQGYDLNDAMLPSSLNDLFTPTELQLRKVRQQEQQYSLSYSPSGNKHSNLSGRISRDATQLSSPDRASKQNQTWRVPFLTKSTQNSSDMLMTLPADYEDKLIEGTAAINIPSNNKSNTLGNTSSSAGSSGGSQHSYLLPQQKKQQGHPQQQLKDDSLQPQDDEVQFYMEDDEAVIMYDSANDHKALNNMTSGNTVNNTSASSSSTTNNYSFPSLVNLPSM</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NMN2</accession>
    <name>A0A1C7NMN2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Putative J domain-containing protein C17A3.05c</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">pi041</name>
        <name evidence="8" type="ORF">A0J61_01528</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000050">
        <property type="protein sequence ID" value="OBZ90403.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NMN2"/>
    <dbReference type="FunCoup" id="A0A1C7NMN2">
        <property type="interactions" value="505"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NMN2"/>
    <dbReference type="InParanoid" id="A0A1C7NMN2"/>
    <dbReference type="OrthoDB" id="1507364at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030544">
        <property type="term" value="F:Hsp70 protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071218">
        <property type="term" value="P:cellular response to misfolded protein"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.110:FF:000070">
        <property type="entry name" value="Endoplasmic reticulum protein, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051100">
        <property type="entry name" value="DnaJ_subfamily_B/C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015399">
        <property type="entry name" value="DUF1977_DnaJ-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43908">
        <property type="entry name" value="AT29763P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43908:SF3">
        <property type="entry name" value="AT29763P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09320">
        <property type="entry name" value="DUF1977"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00625">
        <property type="entry name" value="JDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="270"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="domain" description="J" evidence="7">
        <location>
            <begin position="103"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="53"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="55"/>
            <end position="91"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OBZ90403.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="403" mass="44907" checksum="ED74AA59693F16E6" modified="2016-11-30" version="1">MEINKEEALRCLSIAKNQYGTRNYEAAVRLTKKSLKLYPTDEAESFLLKAEKAATENTNVPPSPSEKSTSSNTTDASNEKPPQNASSGQQTKEVREILSCGTDYYKVLKLDKGCTEVEIKKSYRKLALKFHPDKNKTPGADEAFKLISKAFTVLSDPQKRAIHDAGGGDPEQRGAGGHPGFSGFRTQSYGASPFGEEISPEDLFNMFFGGGGAGIHMDNLHRQGFSFGGSPGFSSATFVGPGFRARTFNTQQQQQQFYQAHQRQGSGLSILLQLLPLIVLFGYTVFAGLVSENTPIFSFQSTSVHSQPRMTSSHGVPYYVNPNSFKPYLQNQYKLSKVEQQVEVDWVRSLQQNCLHERKQQQTRLNNARGAFGFIGRNEKQYQEALNMRLASCEELKRFGSRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NMN7</accession>
    <name>A0A1C7NMN7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Sodium/nucleoside cotransporter 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">Slc28a1</name>
        <name evidence="12" type="ORF">A0J61_01569</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000051">
        <property type="protein sequence ID" value="OBZ90402.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NMN7"/>
    <dbReference type="STRING" id="101091.A0A1C7NMN7"/>
    <dbReference type="InParanoid" id="A0A1C7NMN7"/>
    <dbReference type="OrthoDB" id="6075923at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005337">
        <property type="term" value="F:nucleoside transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015293">
        <property type="term" value="F:symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008276">
        <property type="entry name" value="C_nuclsd_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011657">
        <property type="entry name" value="CNT_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002668">
        <property type="entry name" value="CNT_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011642">
        <property type="entry name" value="Gate_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10590">
        <property type="entry name" value="SODIUM/NUCLEOSIDE COTRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10590:SF4">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 28 MEMBER 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07670">
        <property type="entry name" value="Gate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07662">
        <property type="entry name" value="Nucleos_tra2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01773">
        <property type="entry name" value="Nucleos_tra2_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="72"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="103"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="147"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="179"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="203"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="261"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="425"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="459"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="517"/>
            <end position="540"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="552"/>
            <end position="577"/>
        </location>
    </feature>
    <feature type="domain" description="Concentrative nucleoside transporter N-terminal" evidence="9">
        <location>
            <begin position="184"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="domain" description="Nucleoside transporter/FeoB GTPase Gate" evidence="11">
        <location>
            <begin position="266"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="domain" description="Concentrative nucleoside transporter C-terminal" evidence="10">
        <location>
            <begin position="369"/>
            <end position="575"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="14"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01773"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF07662"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF07670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="OBZ90402.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="578" mass="63399" checksum="31436C6992283A45" modified="2016-11-30" version="1">MDQEKKSTTALPEHTTHTDFDAEKKDSSSQDKEYMFDKMNTVEEAGYDPNENGAEHKEHPIQRSLYQKYRKFILPGMWVLFTGFLIAAFVLQVPKGYNQELLILGLIYLYFTLYVLFVFVPTTIVSKPWNYCIDTTSSYLYAHTSPLTRMVAYGILVGIVIIVTVFTFPEKDESPRIRRLISCFGLFVFIAGTFACSKHRKHVPWNTVSSAILIQFLLALFVFRSTAGHDIFSWLATFAEGYLSKAWHGTDFVFGDTVANAGIFAVSVFPAIIFFAATVQVLYYTGTIPFLLKYLSRACMKILNVSGAESIVTIASPFLGQSENALLIEPLIPLLTKSEFHQIMTCGFATISGSTLYGYIAMGVSGQALLTSCIMSIPCSIAISKIRYPESEESKVAHITEVSHDKDTSNALHAAGKGAAVGINIVLLVLANLIAILALLNAVNAFLTWVGNFVTIQNLTLQLITGYVFVPIAWLIGADDKDLVAVGTLMANKVWANEFVAYQLLTSTYKDQLTARSYLVATYALCGFGNLSSVGMQVGVLNSLAPKRSGDISSLALSAMICGCISTWLSASIAGMLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NMR0</accession>
    <name>A0A1C7NMR0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_01536</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000050">
        <property type="protein sequence ID" value="OBZ90421.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NMR0"/>
    <dbReference type="InParanoid" id="A0A1C7NMR0"/>
    <dbReference type="OrthoDB" id="2290473at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ90421.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="132" mass="15042" checksum="DDD42FDA99FAE573" modified="2016-11-30" version="1">MWLSQCFKRKNVTPKGSLREVYVKKQKATYEISKRLLHGSKKYGKDNIVSTKQANDSKWAPSPEDHDTKHRMTIISYGDATFGSSMRGKVAAPTKRIIQAIQKLAIKMTKLNLFKWTNTLQVIFAISAELKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NMW5</accession>
    <name>A0A1C7NMW5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">CNH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_01526</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000049">
        <property type="protein sequence ID" value="OBZ90425.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NMW5"/>
    <dbReference type="InParanoid" id="A0A1C7NMW5"/>
    <dbReference type="OrthoDB" id="6415790at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="165"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="174"/>
            <end position="184"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ90425.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="554" mass="63376" checksum="BEE3E23E7D0B7AEB" modified="2016-11-30" version="1">MSNDIAQQRLSQPPPYSSEDNSSGHLPLNNPIGSTQPALSCLQLKLLTSSTDHWQNTPYECSCVIEDRFLLLGHSESLQVLDLHHPDQPKTIIWTKVRQMVVIESCRVVLILGGRYKQVRCYSYDALLRLIYAVLSLAWHTRRDTTHDIPTHQAWELVASLTGKAPEDEEDIGTTDSPQSISTATANQQGYPLNLKERLVKKKEEKMPSRQISTIDQLTLSGITKLFYVCNDIILQDFYYKLPESRDALSMEVYQTSNYVFVAVLYRDKIMLWQRKRDHPLRPFYRLKVFWIPSEAKQIAFADDRSTLRHLLVVFSHEATLIELRDSKVQIVRLDSTLERIYQTTWIRDEYEHQLGSDNTNIPPPTLPASLTPPPIQWTSLLQLPFYPDSLPATTLTTDYSIPPSYATVITSLASAPPDPVALPSAVAPQLFFATFGRQSYMIDLAGTLFSTQVYRWLEPPVHIEFIQLGSDWYVVGFGSETVEMLEIKTARSVQRVMRGVPVRFLGRWDLPHRKPKMVFRALFWSCGAANEQVHVYMLKSDMTISVEKDELNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NN71</accession>
    <name>A0A1C7NN71_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">SET domain-containing protein 4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">Setd4</name>
        <name evidence="5" type="ORF">A0J61_01366</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000042">
        <property type="protein sequence ID" value="OBZ90581.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NN71"/>
    <dbReference type="FunCoup" id="A0A1C7NN71">
        <property type="interactions" value="126"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NN71"/>
    <dbReference type="InParanoid" id="A0A1C7NN71"/>
    <dbReference type="OrthoDB" id="341421at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016279">
        <property type="term" value="F:protein-lysine N-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd19177">
        <property type="entry name" value="SET_SETD4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1420.10">
        <property type="entry name" value="Rubisco LSMT, substrate-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1410.10">
        <property type="entry name" value="set domain protein methyltransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015353">
        <property type="entry name" value="Rubisco_LSMT_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036464">
        <property type="entry name" value="Rubisco_LSMT_subst-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001214">
        <property type="entry name" value="SET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046341">
        <property type="entry name" value="SET_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050600">
        <property type="entry name" value="SETD3_SETD6_MTase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044429">
        <property type="entry name" value="SETD4_SET"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13271:SF151">
        <property type="entry name" value="SET DOMAIN-CONTAINING PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13271">
        <property type="entry name" value="UNCHARACTERIZED PUTATIVE METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09273">
        <property type="entry name" value="Rubis-subs-bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00856">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82199">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50280">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="SET" evidence="4">
        <location>
            <begin position="30"/>
            <end position="244"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OBZ90581.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="424" mass="48875" checksum="D971F8F4AD6D4713" modified="2016-11-30" version="1">MIDKSRGTIVRDKKYERFVQWLNDNQFPQTKLTLANFTNTGRGMMATEDIAAGEVIVSVPRRFLITHDSLGKIYGAADSLSSHELLALHLVLLRKDTQSWWKPYIDLLPLHFNTMPVKYAKVLIDHLPESLKQDTLQQKQNMHQDYLSCTQFLKSLPEPLASQPIDPEEFEWAWLCVNTRCIHMNTPGHTVPKGGHIALAPMLDFLNHTTEAKIESGYNTRTQCFEIKTLTPYKKGEQVYINYGPHDNLAILKEYGFVLSQNTYNFVSLDQEVWQLFSEIETEKGFEIKKQILEGAGYAGDYSIKLDEVSFRLLAALRLLALPGTTQPGFDRKVMDWHDVVMGQTDIISPDNERKAWIMLQTICQKAADKATQENDISNHFTQRYPEAEYHPFALYFLRQIWKESNEIIQNTLESVKEKLVQDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NN72</accession>
    <name>A0A1C7NN72_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_01537</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000050">
        <property type="protein sequence ID" value="OBZ90420.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NN72"/>
    <dbReference type="InParanoid" id="A0A1C7NN72"/>
    <dbReference type="OrthoDB" id="2290473at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ90420.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="178" mass="20194" checksum="EF97E022EEF7F822" modified="2016-11-30" version="1">MSAVLQMALSSLTRFRGAIIYPRKRSHSKLQVCPLKYTDLHGASFFSLLSLYGCTPKHIRINEQSLRKIARSVDKESIGTEKKRSSDGLTCHHFFDLTKIGVKVVYGQKKTLVGCSMVLTHHEEYAELTPKDLIEDINSGVLIWDVDPGISDTFITVDSFSNEHNNPQRIRNNFDRIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NNE0</accession>
    <name>A0A1C7NNE0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Mitochondrial import receptor subunit TOM7</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">A0J61_03165</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion outer membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the Tom7 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000132">
        <property type="protein sequence ID" value="OBZ88784.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NNE0"/>
    <dbReference type="FunCoup" id="A0A1C7NNE0">
        <property type="interactions" value="31"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NNE0"/>
    <dbReference type="InParanoid" id="A0A1C7NNE0"/>
    <dbReference type="OrthoDB" id="284357at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005742">
        <property type="term" value="C:mitochondrial outer membrane translocase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030150">
        <property type="term" value="P:protein import into mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012621">
        <property type="entry name" value="Tom7"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08038">
        <property type="entry name" value="Tom7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5" id="KW-1000">Mitochondrion outer membrane</keyword>
    <keyword evidence="6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="15"/>
            <end position="33"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004572"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="OBZ88784.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="13">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="44" mass="5069" checksum="34228FF462E60D24" modified="2016-11-30" version="1">MNDSTKDTLYKVADVTKTIIHWGFIPFVIYLGMTRSNPRPSILK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NNM5</accession>
    <name>A0A1C7NNM5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="15">Helicase SWR1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="15" type="primary">SWR1</name>
        <name evidence="15" type="ORF">A0J61_01228</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SNF2/RAD54 helicase family. SWR1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000036">
        <property type="protein sequence ID" value="OBZ90721.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="FunCoup" id="A0A1C7NNM5">
        <property type="interactions" value="497"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NNM5"/>
    <dbReference type="InParanoid" id="A0A1C7NNM5"/>
    <dbReference type="OrthoDB" id="372624at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000812">
        <property type="term" value="C:Swr1 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140849">
        <property type="term" value="F:ATP-dependent H2AZ histone chaperone activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042393">
        <property type="term" value="F:histone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031492">
        <property type="term" value="F:nucleosomal DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005198">
        <property type="term" value="F:structural molecule activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000725">
        <property type="term" value="P:recombinational repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045815">
        <property type="term" value="P:transcription initiation-coupled chromatin remodeling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd18003">
        <property type="entry name" value="DEXQc_SRCAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18793">
        <property type="entry name" value="SF2_C_SNF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.10810:FF:000005">
        <property type="entry name" value="Photoperiod-independent early flowering 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.850">
        <property type="entry name" value="SWI2/SNF2 ATPases, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10810">
        <property type="entry name" value="Tandem AAA-ATPase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014012">
        <property type="entry name" value="HSA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050520">
        <property type="entry name" value="INO80/SWR1_helicase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038718">
        <property type="entry name" value="SNF2-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049730">
        <property type="entry name" value="SNF2/RAD54-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000330">
        <property type="entry name" value="SNF2_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45685:SF1">
        <property type="entry name" value="HELICASE SRCAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45685">
        <property type="entry name" value="HELICASE SRCAP-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07529">
        <property type="entry name" value="HSA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00176">
        <property type="entry name" value="SNF2-rel_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51204">
        <property type="entry name" value="HSA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0010">Activator</keyword>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="8" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5 15" id="KW-0347">Helicase</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HSA" evidence="14">
        <location>
            <begin position="315"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="12">
        <location>
            <begin position="631"/>
            <end position="796"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="13">
        <location>
            <begin position="1168"/>
            <end position="1318"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="441"/>
            <end position="561"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1378"/>
            <end position="1431"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="58"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="94"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="451"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="500"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="526"/>
            <end position="561"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="1383"/>
            <end position="1405"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="1412"/>
            <end position="1430"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009220"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="OBZ90721.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="1467" mass="170934" checksum="E257C3FC6BCE2482" modified="2016-11-30" version="1">MSPISSKDNASIIKANNNDEDSDSSNSKKQARLSKRTQIIEEKLKNKTITSLFDTDGDLSRHNIIEGSRRTRKRTQNYEPSSPQTTKRKRATSIPKQKSPPLSKQTSPALPKISTVTKKTTKPLIKNAKAKLLPSPTNSEETTRNELINNRLQRMETIQQHHDASVKELYQLELFQNMLDYNPDAFINDVRYNKYMEDYDMWESLRCSQTSIQDPSLVDLLQSAVHESKRIPNHQENEYVNTIHTGTGLRRINRQFATLKEYLDSFYAADEGIEDHTPVSREAYIQKERLIRQRLYDLEQRGGFSTELQHIAHRRPHQPGFPKQTVVHDNLLADVAATAKNFHTNIRYRKSAARKCAKAVERYWEQIRTQDERVQREENKRIVRLAKWTSQQIKRKWKVVERVCEARYKEVLKEQQAKEGRRHLELILEHSEQMLGVRKEELRQQQQIDTTEQDEEVKDEDDWHFDEQDDERDHIIEESSDDDDSELKGLEEDQDLTVEELLKKYHGVEEHETDVDESEGAMSSSDVEEADNEEEEDYDMVEDEEDVPIEEDGESEDDDAELNALKDDAELSIESLMEKYNGKNNESPKIEQEEIQPTGNTLATTKVNTRIPHLLRGSLREYQHVGLDWLASLYNNGLNGILADEMGLGKTIQTISLLAYLACEKGVWGPHLIVVPTSVILNWEMEFKKWLPGFKIMAYYGSPKERKEKRSGWSKDNAFHVCITSYQLVLQDQNVFRRKAWQYLILDEAHHIKNFRSQRWQVLLNFNSKRRLLLTGTPLQNNLMELWSLLYFLMPNGVSQDMPVGFANLKEFQEWFSHPVDRMIENHQEHGIDEESRAAIQKLHIVLRPYLLRRLKLDVEKQMPEKHEHIVYCRLSNRQRFLYDDFMSRAKTKETLASGSFLSIINCLMQLRKVCNHPDLFEERPILTSFAMDGQVQLAGQSLERFVRKRLVERSDENVSLRFLNLILTDIMSQVVAQETMRLEASEEILKTIADYQKRISVAESRGLHSKGDYTDLKRYAKYQEVVSYRKAVEKWQTIHYVNHFRCSRQSFYDASLIQMLSPAMPYMFVKNPRHYFDYCEAVYNAVQSYKERIENHLDIIQEFGFVTPKVVIQADYDQHHPSVSSLPDQLQLAHSVENDIFHPIESRLSIAFPDKRLLQYDCGKLQKLDTLLRNLAAGGHRALIFTQMTRVLDVLXIFLNMHGHRYLRLDGATKVEQRQVLTEHFNNDKRILCFILSTRSGGLGINLTGADTVIFYDSDWNPSMDKQCQDRAHRIGQTRDVHIYRFVTEFTIEENIFKKANQKRMLDNVVIQEGDFTDDYFNKNEWWKDLPEVVGSAAEQPKTMDYEQALLEAEDENDAAAAIAARNEMNMDDNDFDEQARSTRQPSEVSSRPLSPSTQAPSTQRSREQTEAESADEEMTHDDEEEEEMKDMQLDVGHVDQYMLQFWEREMVGVDLGFGGVSLQQN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NPE4</accession>
    <name>A0A1C7NPE4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Glycoside hydrolase family 5 C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_01179</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000034">
        <property type="protein sequence ID" value="OBZ90769.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NPE4"/>
    <dbReference type="STRING" id="101091.A0A1C7NPE4"/>
    <dbReference type="InParanoid" id="A0A1C7NPE4"/>
    <dbReference type="OrthoDB" id="196858at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041036">
        <property type="entry name" value="GH5_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18564">
        <property type="entry name" value="Glyco_hydro_5_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glycoside hydrolase family 5 C-terminal" evidence="2">
        <location>
            <begin position="12"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="144"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="149"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="159"/>
            <end position="171"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF18564"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ90769.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="246" mass="27886" checksum="CA3B84B6B7DD55B1" modified="2016-11-30" version="1">MKQYLTKNGCPPYIRRVAGKVVLETFDPVSNQYKLTIIAKHEPSDAYQARKKALSSKQKQLWCTDIRFHELMFPHGLDIQVEPHEMIQFQVTTKGHKCLKLFTTEQAMDGKQISLTMSPLSPKKSRDAHSYCYNGELFPPTPSVKPAASSINVSNTTTHSEKADKETKDEQLVEPTIQENTRKEMTENPVQVPKGYVLVPENPSTRNNMVIITDELSFNGQQLSVMFLAMVLCYYMGKLTSCHCPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NQA8</accession>
    <name>A0A1C7NQA8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glucose-induced degradation protein 8</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_00688</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000016">
        <property type="protein sequence ID" value="OBZ91283.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NQA8"/>
    <dbReference type="STRING" id="101091.A0A1C7NQA8"/>
    <dbReference type="InParanoid" id="A0A1C7NQA8"/>
    <dbReference type="OrthoDB" id="2415936at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013144">
        <property type="entry name" value="CRA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024964">
        <property type="entry name" value="CTLH/CRA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006595">
        <property type="entry name" value="CTLH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050618">
        <property type="entry name" value="Ubq-SigPath_Reg"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12864">
        <property type="entry name" value="RAN BINDING PROTEIN 9-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10607">
        <property type="entry name" value="CTLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00757">
        <property type="entry name" value="CRA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50897">
        <property type="entry name" value="CTLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CTLH" evidence="1">
        <location>
            <begin position="56"/>
            <end position="112"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50897"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ91283.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="213" mass="24532" checksum="04669928CB953E79" modified="2016-11-30" version="1">MDAECQSIVIEYLIHNCFKNTVNAFIKERRRLQLCSKPLLINGDLKKLPTKGSMDNGLVQAVRKGDITLAFELIQQYFPSLTQDSIPSSEHVLFKLKCQQFIEIIRSSCPTSELEAIRYAQMHLKPIHSRDKELVKEVTALIAYTDPYKSQSKYLLTQERREQLASELNYTLLAYCDLPVETSIEKLTKQYSVVQQELEDCSSNCSYREKLAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NQG1</accession>
    <name>A0A1C7NQG1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_00618</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000014">
        <property type="protein sequence ID" value="OBZ91361.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NQG1"/>
    <dbReference type="InParanoid" id="A0A1C7NQG1"/>
    <dbReference type="OrthoDB" id="2247533at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ91361.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="126" mass="14525" checksum="435CF17EDEDBC106" modified="2016-11-30" version="1">MSLNFFKDRTTKTDATLHFSSVLDDLKKISTSSTPLDIDQFLKNADVQLEQDQSLYKEAVQEEELPTRLEVNKQYSVHNTRMLANTLLDLSKTLPEAKQKIAECKEEVKICLEKNTQIMKDMESIQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NQW0</accession>
    <name>A0A1C7NQW0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Polyadenylate-binding protein 4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">PABPC4</name>
        <name evidence="8" type="ORF">A0J61_00449</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the polyadenylate-binding protein type-1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000010">
        <property type="protein sequence ID" value="OBZ91501.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NQW0"/>
    <dbReference type="STRING" id="101091.A0A1C7NQW0"/>
    <dbReference type="InParanoid" id="A0A1C7NQW0"/>
    <dbReference type="OrthoDB" id="6159137at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010629">
        <property type="term" value="P:negative regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009967">
        <property type="term" value="P:positive regulation of signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd00590">
        <property type="entry name" value="RRM_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.330:FF:000383">
        <property type="entry name" value="Sex lethal, isoform D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1900.10">
        <property type="entry name" value="c-terminal domain of poly(a) binding protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050502">
        <property type="entry name" value="Euk_RNA-bind_prot"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036053">
        <property type="entry name" value="PABP-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002004">
        <property type="entry name" value="PABP_HYD_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48025">
        <property type="entry name" value="OS02G0815200 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48025:SF1">
        <property type="entry name" value="RRM DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00658">
        <property type="entry name" value="MLLE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00517">
        <property type="entry name" value="PolyA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63570">
        <property type="entry name" value="PABC (PABP) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51309">
        <property type="entry name" value="PABC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 4" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="6">
        <location>
            <begin position="118"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="6">
        <location>
            <begin position="217"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="domain" description="PABC" evidence="7">
        <location>
            <begin position="562"/>
            <end position="635"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="293"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="293"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="303"/>
            <end position="312"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51309"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OBZ91501.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="635" mass="71197" checksum="BD03BFBF011126E5" modified="2016-11-30" version="1">MTTKKPVIKLPPNNKSTYVNRPGSYRDVTQYESTFVSKDLFFEDEENRLSYSDIESLFQEYNILNIKRERGGGYLSFPDSKIADRVYSLFNGYTFANQAILKLRISADDMDEPQPEGSLLEVRNLPSRIDHNALYDIFRPYGPLNICKTIPEEGTQNTKALIQYFSQEDSDNAVSKLNGKEIENNVIRISSFVMSNLATSRNNTTMENKPEGLIDFMNLYVKNLDPTVNSTELFELFRSFGRIVSARVMSNPQNGLSKGYGFVSFSKPEEAALALQKMKGFQFRNKSMIVAYHEPKKPRQEKSSSTTTSSFHSPPPSAPIDYATTPYFETRHPHEGLMNGLNMDHTDHLAMNMKDLAIGTTMQRKVSAVESNYPPRHSPPFVARPSLASLASGASIQPVPPHAYKKVESRKIEEDSLRPLRRKSSLESVNSIMTESSAQMQRVRMTEAVKNCGSFGKELNDIVDMLLTLKRKERSLCLFNTDFLKEKISAALEALEICEDEDVVIEQTPIKPMAMVSTEISPPRSPVKKPSVYQNPVAATVRKSKAIPIVAPPTVNSSKTMEIEALLSSLEGKSTHEKKQLLGDQLFPLVKATGVKPAPKITIRLLDTVKLEELARIMFDKDALRVQVDKAAASL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NRE9</accession>
    <name>A0A1C7NRE9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">PDZ domain-containing protein C23G3.12c</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">A0J61_00273</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S1C family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000005">
        <property type="protein sequence ID" value="OBZ91682.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NRE9"/>
    <dbReference type="STRING" id="101091.A0A1C7NRE9"/>
    <dbReference type="InParanoid" id="A0A1C7NRE9"/>
    <dbReference type="OrthoDB" id="4217619at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06786">
        <property type="entry name" value="cpPDZ1_ScNma111-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd06719">
        <property type="entry name" value="PDZ2-4_Nma111p-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.42.10">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.10">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001478">
        <property type="entry name" value="PDZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025926">
        <property type="entry name" value="PDZ-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036034">
        <property type="entry name" value="PDZ_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009003">
        <property type="entry name" value="Peptidase_S1_PA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043504">
        <property type="entry name" value="Peptidase_S1_PA_chymotrypsin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001940">
        <property type="entry name" value="Peptidase_S1C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46366:SF1">
        <property type="entry name" value="PDZ DOMAIN-CONTAINING PROTEIN C1685.05"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46366">
        <property type="entry name" value="PRO-APOPTOTIC SERINE PROTEASE NMA111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12812">
        <property type="entry name" value="PDZ_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13365">
        <property type="entry name" value="Trypsin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00834">
        <property type="entry name" value="PROTEASES2C"/>
    </dbReference>
    <dbReference type="SMART" id="SM00228">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50156">
        <property type="entry name" value="PDZ domain-like"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50494">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PDZ" evidence="3">
        <location>
            <begin position="327"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="domain" description="PDZ" evidence="3">
        <location>
            <begin position="786"/>
            <end position="872"/>
        </location>
    </feature>
    <feature type="domain" description="PDZ" evidence="3">
        <location>
            <begin position="894"/>
            <end position="968"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="979"/>
            <end position="1006"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="997"/>
            <end position="1006"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010541"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00228"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OBZ91682.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="1054" mass="116698" checksum="EE03DFAD7278FEF9" modified="2016-11-30" version="1">MDDSQHPLVVSTPPLRGPVESPAPAEAGDMATNLKPHRGSMSLATTQFEQQAPVDSRALRGRSKSIAFGAHAWNPRPPMDYFSPANTSGVPYKARSWEPTLEKAIRAIVSIKASHVRSFDTETSGGYTATGFIVDAKRGIILTNRHVVSPAPIVAQAVLTNYEEVDLKPVYRDPVHDFGFMQFDPTRIKFMELEEIELSPERAKVGLDIRVVGNDAGEKLSILAGTLARLDRRAPEYGVGEYNDFNTFYLQAASGTSGGSSGSPVLDIDGHAVALNAGGASRASSSYYLPLDRVKRALKYIQAGKSVPRGTLQTEFEYLPYNEVRRLGLKASIEEKVRNKFPEETGMLVVRSLLPKGPADNILVPGDIIIGCNGKMVPHFIALFEILDDMVGKEISLTISRGKKVQEVKVIVQDLHSITPNRFVEIGGGVVHELSYQLAKSYSQPTSGVYVATSGHMLASASAWRKSIIVSVNNIPTPNLDAFIEAMKSLPDGARVPIRFYALHKAYKDKVMIMHVDRHWHKFRIAVRNDVSGLWDYTDMPSPPQKIPYTPSSASFPRLDPSLALAEKLMPSFVAIDFYLPYLVDGMKATQFYGTGFIVSTNPPLIVCDRDTIPIGLGDIFITFANSIIIPGRLLFLHPFYNYVILTYDPKLIGDTPVKPIEFSEKELNQGDEANFIGIGSDHSVIMKKTTVSSVSNIGTRECSPPRWRAMNVEGIKIDDSSNSQGGLITDDNGLVHALWISYSSQNEKGKDVSFMSGLLASLVKPTIDQFLNNGDKIVFKGLDVELWTMRIAAARTLGLSDEWVKKIEESGATRHTLLYVLNVLDERSPCAKVLNVGDVILSLNGKLVTRMSHLMHVNQQDNVDMVILRDGKEMNVTVPLSEFSGYETTRVIGWQGALIQKPYKSVLEQVRNVPVGVYVSCTLYGSPASNVLRPGVWIVEVQGKPVKDLDSFLEVVHEYEAEACRRRRSSYIPPIRRTSKDNDVREEENAAIVPEFSDEDEDDDNDEGYIRIKTVSRNETVRVVAVKIDLHYWDSWQLVRDDQSVSGWSAHNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NRS2</accession>
    <name>A0A1C7NRS2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Mitochondrial distribution and morphology protein 35</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">MDM35</name>
        <name evidence="4" type="ORF">A0J61_00133</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the TRIAP1/MDM35 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000003">
        <property type="protein sequence ID" value="OBZ91821.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NRS2"/>
    <dbReference type="FunCoup" id="A0A1C7NRS2">
        <property type="interactions" value="107"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NRS2"/>
    <dbReference type="InParanoid" id="A0A1C7NRS2"/>
    <dbReference type="OrthoDB" id="19091at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005758">
        <property type="term" value="C:mitochondrial intermembrane space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990050">
        <property type="term" value="F:phosphatidic acid transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045332">
        <property type="term" value="P:phospholipid translocation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007918">
        <property type="entry name" value="MDM35_apoptosis"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46403">
        <property type="entry name" value="TP53-REGULATED INHIBITOR OF APOPTOSIS 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46403:SF1">
        <property type="entry name" value="TP53-REGULATED INHIBITOR OF APOPTOSIS 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05254">
        <property type="entry name" value="UPF0203"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51808">
        <property type="entry name" value="CHCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="63"/>
            <end position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006196"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OBZ91821.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="82" mass="9374" checksum="F8F2F4E917C5ED54" modified="2016-11-30" version="1">MSSSIGPNCTELKQKYDNCFNKWYSEKFLKGDTTPECEDLFKDYRACVMSALKEKGIDKLLDDSRKEAPFPSAEQKQDHSSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NRT8</accession>
    <name>A0A1C7NRT8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_00183</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000004">
        <property type="protein sequence ID" value="OBZ91728.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NRT8"/>
    <dbReference type="InParanoid" id="A0A1C7NRT8"/>
    <dbReference type="OrthoDB" id="2279350at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="278"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ91728.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="297" mass="35352" checksum="210340DA76C88DE6" modified="2016-11-30" version="1">MEFEEVHDYINQDKAQQNHSTSSLDHLSSLDQVNPYNALFQPSQRNTLSGFVHRLRQQSSKTRFVREYKKMASLFDTTHPEIYSEKPKSDIEDDASLRIRDRMKPHDDTVNQLVIKKRPLKKVVINESANQICDHAISLSPYTPDASITLPEALDGLRQTIQILYDKIEYETNRIHMYQEEMARYRDQCGWMDSQLDAIHSSFDLFYRDTMPEMKAQRERMIQNELKVRIHQKKHKTQKQRFERYRKAMSIDTRLTELKKKIQVAWKQDEVWLGIRDWGLLSVILIVLMVTTFVWQF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NRW5</accession>
    <name>A0A1C7NRW5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Ras-like protein 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">RAS2</name>
        <name evidence="10" type="ORF">A0J61_01944</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Lipid-anchor</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the small GTPase superfamily. Ras family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000068">
        <property type="protein sequence ID" value="OBZ89994.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NRW5"/>
    <dbReference type="STRING" id="101091.A0A1C7NRW5"/>
    <dbReference type="InParanoid" id="A0A1C7NRW5"/>
    <dbReference type="OrthoDB" id="5976022at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00876">
        <property type="entry name" value="Ras"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000080">
        <property type="entry name" value="Ras-like GTPase Ras1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001806">
        <property type="entry name" value="Small_GTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020849">
        <property type="entry name" value="Small_GTPase_Ras-type"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24070">
        <property type="entry name" value="RAS, DI-RAS, AND RHEB FAMILY MEMBERS OF SMALL GTPASE SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00071">
        <property type="entry name" value="Ras"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00449">
        <property type="entry name" value="RASTRNSFRMNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00175">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00173">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00174">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51419">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51421">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="8" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0488">Methylation</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-0636">Prenylation</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008344"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023289"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OBZ89994.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="188" mass="21346" checksum="63DF4D36983BAB7F" modified="2016-11-30" version="1">MIGEGGVGKSAITIQFFKSHFVDEYDPTIEDSYRKQCVIDGECAMLDILDTAGQEEYSAMREQYMRNGEGFVLVYDITSFRSFEQIQKLVEQIVRVKDVDLLPVILVGNKCDMEQDRQVPIHIGKALANQYGCEFLETSAKERIRIDETFHGIVQAIKRVNQEKQDADDRFEDNDGALCCLGGECILM</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NS79</accession>
    <name>A0A1C7NS79_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="8">60S ribosomal protein L11</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">rpl-11_2</name>
        <name evidence="8" type="ORF">A0J61_01828</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules. The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain. The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the universal ribosomal protein uL5 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000063">
        <property type="protein sequence ID" value="OBZ90104.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NS79"/>
    <dbReference type="FunCoup" id="A0A1C7NS79">
        <property type="interactions" value="386"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NS79"/>
    <dbReference type="InParanoid" id="A0A1C7NS79"/>
    <dbReference type="OrthoDB" id="1734943at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1440.10:FF:000002">
        <property type="entry name" value="60S ribosomal protein L11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1440.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002132">
        <property type="entry name" value="Ribosomal_uL5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031309">
        <property type="entry name" value="Ribosomal_uL5_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020929">
        <property type="entry name" value="Ribosomal_uL5_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022803">
        <property type="entry name" value="Ribosomal_uL5_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057266">
        <property type="entry name" value="Ribosomal_uL5_euk/arc-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031310">
        <property type="entry name" value="Ribosomal_uL5_N"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003258">
        <property type="entry name" value="PRK04219.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11994">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L11-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00281">
        <property type="entry name" value="Ribosomal_L5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00673">
        <property type="entry name" value="Ribosomal_L5_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002161">
        <property type="entry name" value="Ribosomal_L5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55282">
        <property type="entry name" value="RL5-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00358">
        <property type="entry name" value="RIBOSOMAL_L5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 5 8" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Large ribosomal subunit protein uL5 N-terminal" evidence="6">
        <location>
            <begin position="10"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="domain" description="Large ribosomal subunit protein uL5 C-terminal" evidence="7">
        <location>
            <begin position="67"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004021"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003930"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00673"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OBZ90104.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="178" mass="20375" checksum="71247AF473E872C8" modified="2016-11-30" version="1">MSAEQKTAVNPMRNLQIEKLVLNICVGESGDRLTRAAKVLEQLTGQTPVYSKARYTVRTFSIRRNEKISVHVTVRGPKAEEILERGLKVKEYELKARNFSQTGNFGFGIDEHIDLGIKYDPSIGIYGMDYYVVMGRPGNRVSRRKHCKAKVGVTHRIKKEETQEWFKNRFDGVISNKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NTH1</accession>
    <name>A0A1C7NTH1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Vacuolar-sorting protein SNF8</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">snf8</name>
        <name evidence="2" type="ORF">A0J61_01136</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SNF8 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000033">
        <property type="protein sequence ID" value="OBZ90794.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NTH1"/>
    <dbReference type="FunCoup" id="A0A1C7NTH1">
        <property type="interactions" value="271"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NTH1"/>
    <dbReference type="InParanoid" id="A0A1C7NTH1"/>
    <dbReference type="OrthoDB" id="283883at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000814">
        <property type="term" value="C:ESCRT II complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:1904669">
        <property type="term" value="P:ATP export"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000122">
        <property type="term" value="P:negative regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006623">
        <property type="term" value="P:protein targeting to vacuole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043328">
        <property type="term" value="P:protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.10:FF:000085">
        <property type="entry name" value="Vacuolar-sorting protein SNF8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016689">
        <property type="entry name" value="ESCRT-2_cplx_Snf8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040608">
        <property type="entry name" value="Snf8/Vps36"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12806">
        <property type="entry name" value="EAP30 SUBUNIT OF ELL COMPLEX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12806:SF0">
        <property type="entry name" value="VACUOLAR-SORTING PROTEIN SNF8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04157">
        <property type="entry name" value="EAP30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009834"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ90794.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="211" mass="24084" checksum="FABE81189B63F5EE" modified="2016-11-30" version="1">MEVFKVNLQEFAQKHRKDIRKDPTFRAHFQRMCANIGVDPLASNKGFWADLLGVGDFYYELGIQIIEACILSRANDGGLTELSEIMRRVQTMRGGNYGKNKEQQQISEDDITRAIKTLTPLSGGYEVLQIGERKLVRSVPKELDKDQAALLLLAQKTGYVDHEMIRNQLGWTIERTETATQHLLQDGIAWLDRFGDKDAYWIPSYFTGNNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7LT31</accession>
    <name>A0A1C7LT31_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Putative 37S ribosomal protein S4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">A0J61_11905</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uS4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01002673">
        <property type="protein sequence ID" value="OBZ67991.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7LT31"/>
    <dbReference type="FunCoup" id="A0A1C7LT31">
        <property type="interactions" value="49"/>
    </dbReference>
    <dbReference type="InParanoid" id="A0A1C7LT31"/>
    <dbReference type="OrthoDB" id="3356781at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005763">
        <property type="term" value="C:mitochondrial small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042274">
        <property type="term" value="P:ribosomal small subunit biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00165">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.290.10">
        <property type="entry name" value="RNA-binding S4 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022801">
        <property type="entry name" value="Ribosomal_uS4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002942">
        <property type="entry name" value="S4_RNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036986">
        <property type="entry name" value="S4_RNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11831">
        <property type="entry name" value="30S 40S RIBOSOMAL PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11831:SF4">
        <property type="entry name" value="SMALL RIBOSOMAL SUBUNIT PROTEIN US4M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01479">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00363">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55174">
        <property type="entry name" value="Alpha-L RNA-binding motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50889">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4 8" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="3 6" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="2" id="KW-0699">rRNA-binding</keyword>
    <feature type="domain" description="RNA-binding S4" evidence="7">
        <location>
            <begin position="4"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007465"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00182"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OBZ67991.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="131" mass="15115" checksum="18066857AE33B2EC" modified="2016-11-30" version="1" fragment="single">ELERRLDFVVFRSNFCPSVYAARQLCVHGKVLVNGKKMAYPSHKLKDGDVITVDPHAIQFLKGEKGQELDFTPKPYSQPFLFVPEYLEVNYNTCQTVFLRSPVSRPGRSEIPSPFPPDFHSLAYEYYARNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MU47</accession>
    <name>A0A1C7MU47_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_11546</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01002174">
        <property type="protein sequence ID" value="OBZ80405.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MU47"/>
    <dbReference type="InParanoid" id="A0A1C7MU47"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ80405.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="69" mass="7630" checksum="29E00668731440A5" modified="2016-11-30" version="1">MSSTSSTKLYECHCDKCGVSTKRKYVNNATIQAKKVIKKTRVISETQTESDAEIAVTSTNQGEFPIVDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MU82</accession>
    <name>A0A1C7MU82_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_11551</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01002180">
        <property type="protein sequence ID" value="OBZ80400.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MU82"/>
    <dbReference type="InParanoid" id="A0A1C7MU82"/>
    <dbReference type="OrthoDB" id="2299396at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="19"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ80400.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="273" mass="31149" checksum="236A0382D8F76186" modified="2016-11-30" version="1" fragment="single">IQVAPPRSSKRSYLVANIKERLEELKPNLANEEDGAEEDKTAMKKFNRQRRQAIEELMDSNSRDLSADLNKLLMIQGIMKIDFKTNADFAAYAKEKKQDKYGNPRRLPLSLKQELEEALEDFRDDGEFKKLKKKLMLINIDLEGVEERVVSVLLSLLDHMTVGKKQANEMRIQSGALSSICHLFKLSMNHDAHGYNKILFDTDALKNRCPDYIVEVGTGEDDLIVNLVAEVKGENSKKSGVSLDTYRLGLFGLHMLWKYKLKNSLVLQVEGMM</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MUI5</accession>
    <name>A0A1C7MUI5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_11406</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001999">
        <property type="protein sequence ID" value="OBZ80545.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7MUI5"/>
    <dbReference type="InParanoid" id="A0A1C7MUI5"/>
    <dbReference type="OrthoDB" id="2237231at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="338"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ80545.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="338" mass="38658" checksum="F8C53B4D9C5EC492" modified="2016-11-30" version="1" fragment="single">MFSSSTSQNSSQLFKCECSACQLSIXDGYTFIKKRTYNDHXKRDALKKLKTEVPSSSLTTIPADSATDAANVEEVVTSIDCQAANESYPIEDIDQEGQYEQNQSKRLPSTPIASLLFVMIVLLRKNQLTDASCETVMLFCNMVLCLTDEAFRFPRSATTFEGWCNSMKFFSAFIKEYASCITCHAIHPYDTEDEKKQVQQQCYCLDSGIFSKPSICEEELVAPNQYGTIAPVRSFFNNSLIDTLRSFFLRDEFVESINEWKXRQTLPETLSDIYAGQVWKNFKLRETDDKPFVLQSDYNLMLTLNCDWFQAYKDGYSVGAIYLTIQNLPREVRNLRSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MUN2</accession>
    <name>A0A1C7MUN2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Mitochondrial carrier protein LEU5</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">LEU5_1</name>
        <name evidence="13" type="ORF">A0J61_11442</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01002037">
        <property type="protein sequence ID" value="OBZ80510.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MUN2"/>
    <dbReference type="FunCoup" id="A0A1C7MUN2">
        <property type="interactions" value="127"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7MUN2"/>
    <dbReference type="InParanoid" id="A0A1C7MUN2"/>
    <dbReference type="OrthoDB" id="270584at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002167">
        <property type="entry name" value="GDC-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002067">
        <property type="entry name" value="MCP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24089">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00928">
        <property type="entry name" value="GRAVESDC"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00926">
        <property type="entry name" value="MITOCARRIER"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 10 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 10 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 11" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="118"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="180"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="10">
        <location>
            <begin position="13"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="10">
        <location>
            <begin position="112"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="10">
        <location>
            <begin position="244"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="13">
        <location>
            <position position="315"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU000488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="OBZ80510.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="315" mass="35413" checksum="E5679DEA0D96DCCD" modified="2016-11-30" version="1" fragment="single">MSTSEKNRTQSLDYVIRSGIAGGIAGCMAKTSVAPLDRIKILFQSRNPAFEKYAGTFTGAFKAGRDIFKDAGIVGLFQGHSVTLFRIFPYAAIKFVAYEQYRAILMPTRKQETSTKQFIAGSMAGVTSVFFTYPLDLVRVRLAYHVEKPGQHRPSLRETVQHIMKETAALHFPPLNFYRGFFPTVAGMIPYAGVSFWTYHIITQLFRFNPLISPYTRAPLTFSTDALTSKQKRVLEKPPLRTWAELLCGGIAGLVAQTSSYPLEVIRRRMQVGGLLDPDKFVRFTETAKEIYRIKGFKGYYVGLSIGYIKVVPMV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MUQ6</accession>
    <name>A0A1C7MUQ6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_11464</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01002063">
        <property type="protein sequence ID" value="OBZ80487.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MUQ6"/>
    <dbReference type="STRING" id="101091.A0A1C7MUQ6"/>
    <dbReference type="InParanoid" id="A0A1C7MUQ6"/>
    <dbReference type="OrthoDB" id="2505730at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040521">
        <property type="entry name" value="KDZ"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18758">
        <property type="entry name" value="KDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ80487.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="166" mass="19117" checksum="58A20792B20EF94B" modified="2016-11-30" version="1">MYCFAESVEVNSFKANNNNNRNNSSERYYENDVFSMSCARHVVHERLLNIHGGEGYIPQVCCSLRWAYVESQPSKKKYAIMYDIVCLVRKGLKSSCSSHHVNNINDLQRRFPVWKEDTWYGVTAFYAYAHTMACQVNYNPKYIPNFGCTAARAVRGSGHTWTVSCQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MV23</accession>
    <name>A0A1C7MV23_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_11344</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001929">
        <property type="protein sequence ID" value="OBZ80607.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MV23"/>
    <dbReference type="STRING" id="101091.A0A1C7MV23"/>
    <dbReference type="InParanoid" id="A0A1C7MV23"/>
    <dbReference type="OrthoDB" id="2447509at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45786:SF74">
        <property type="entry name" value="ATP-DEPENDENT DNA HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45786">
        <property type="entry name" value="DNA BINDING PROTEIN-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ80607.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="66" mass="7409" checksum="DA70B3A83898ED34" modified="2016-11-30" version="1">MGVNLDSTVQNLRGGAYAFRIHRSIYHRIGSLLPNENERPAFAQIYVFDASTEINNRHAVANHVDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MV46</accession>
    <name>A0A1C7MV46_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">A0J61_11646</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01002293">
        <property type="protein sequence ID" value="OBZ80306.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MV46"/>
    <dbReference type="STRING" id="101091.A0A1C7MV46"/>
    <dbReference type="InParanoid" id="A0A1C7MV46"/>
    <dbReference type="OrthoDB" id="3269380at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051580">
        <property type="entry name" value="ZnF-Chromatin_assoc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23057">
        <property type="entry name" value="JUXTAPOSED WITH ANOTHER ZINC FINGER PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23057:SF0">
        <property type="entry name" value="JUXTAPOSED WITH ANOTHER ZINC FINGER PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="7">
        <location>
            <begin position="26"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="41"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="54"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OBZ80306.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="118" mass="13565" checksum="DDA22390316E4BF9" modified="2016-11-30" version="1" fragment="single">YHLREAKGSSGHGNFSGEGEVNAKPYHCHVPGCKKAYRTVNGLRYHQQNGHNAQPSTSPSSQTNPPSQQQIMTAAIQQMQMHPSQQQQQQSMLNLQQQQNQHYRIQQQREKWQMNNPM</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MVN0</accession>
    <name>A0A1C7MVN0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">OTU domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_10986</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001566">
        <property type="protein sequence ID" value="OBZ80965.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MVN0"/>
    <dbReference type="InParanoid" id="A0A1C7MVN0"/>
    <dbReference type="OrthoDB" id="2379842at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd22744">
        <property type="entry name" value="OTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ80965.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="104" mass="12093" checksum="855BA70E1BE6DA4E" modified="2016-11-30" version="1" fragment="single">ELIIRKRKPNQVAYGKSDFVFDIHHRPNKRTRGNINSTIRSILSASIDESEITAYLDPKADGNCGFRAVAFLIDRNNSNYQDGDQYLEVRRKMLQTYKNIKPLY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MVQ2</accession>
    <name>A0A1C7MVQ2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Checkpoint protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">hus1</name>
        <name evidence="5" type="ORF">A0J61_11061</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 4">Belongs to the HUS1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001635">
        <property type="protein sequence ID" value="OBZ80890.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MVQ2"/>
    <dbReference type="FunCoup" id="A0A1C7MVQ2">
        <property type="interactions" value="428"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7MVQ2"/>
    <dbReference type="InParanoid" id="A0A1C7MVQ2"/>
    <dbReference type="OrthoDB" id="337750at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030896">
        <property type="term" value="C:checkpoint clamp complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035861">
        <property type="term" value="C:site of double-strand break"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000724">
        <property type="term" value="P:double-strand break repair via homologous recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044778">
        <property type="term" value="P:meiotic DNA integrity checkpoint signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033314">
        <property type="term" value="P:mitotic DNA replication checkpoint signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031573">
        <property type="term" value="P:mitotic intra-S DNA damage checkpoint signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006289">
        <property type="term" value="P:nucleotide-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000723">
        <property type="term" value="P:telomere maintenance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.70.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016580">
        <property type="entry name" value="HUS1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007150">
        <property type="entry name" value="HUS1/Mec3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12900:SF0">
        <property type="entry name" value="CHECKPOINT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12900">
        <property type="entry name" value="MITOTIC AND DNA DAMAGE CHECKPOINT PROTEIN HUS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04005">
        <property type="entry name" value="Hus1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF011312">
        <property type="entry name" value="Cell_cycle_HUS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRNR" id="PIRNR011312"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OBZ80890.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="236" mass="26824" checksum="8AEB50740E57F863" modified="2016-11-30" version="1">MFTEFRLQSQQVNNELHFVFNLSNLLLITKDLVDCTRITVGLKSSNGNVSLSFRWISESFKGSTDESKKDLPVQIVTAEKIQNIRNPCASERPDTYILLPDVNILKSTAERFKALSNFITLSANMQGEFKIEIQSPFAVCSARYENLQHPELVGHDISSRDPEHFSSACVRSDDFVHFLSCTHLEPDNIICSITNERQVAFLIFLSIDTYQNEDAPLRSLNSQDCQITVQLPLYLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MW29</accession>
    <name>A0A1C7MW29_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Transposon Ty3-I Gag-Pol polyprotein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">TY3B-I_1</name>
        <name evidence="8" type="ORF">A0J61_10949</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001533">
        <property type="protein sequence ID" value="OBZ81002.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MW29"/>
    <dbReference type="STRING" id="101091.A0A1C7MW29"/>
    <dbReference type="InParanoid" id="A0A1C7MW29"/>
    <dbReference type="OrthoDB" id="3227343at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003964">
        <property type="term" value="F:RNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015074">
        <property type="term" value="P:DNA integration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.10:FF:000032">
        <property type="entry name" value="Retrovirus-related Pol polyprotein from transposon 297-like Protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.340.70:FF:000001">
        <property type="entry name" value="Retrovirus-related Pol polyprotein from transposon gypsy-like Protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.340.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043502">
        <property type="entry name" value="DNA/RNA_pol_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001584">
        <property type="entry name" value="Integrase_cat-core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041588">
        <property type="entry name" value="Integrase_H2C2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050951">
        <property type="entry name" value="Retrovirus_Pol_polyprotein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041373">
        <property type="entry name" value="RT_RNaseH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37984">
        <property type="entry name" value="PROTEIN CBG26694"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37984:SF5">
        <property type="entry name" value="PROTEIN NYNRIN-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17921">
        <property type="entry name" value="Integrase_H2C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17917">
        <property type="entry name" value="RT_RNaseH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00665">
        <property type="entry name" value="rve"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56672">
        <property type="entry name" value="DNA/RNA polymerases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50994">
        <property type="entry name" value="INTEGRASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0540">Nuclease</keyword>
    <keyword evidence="2" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0695">RNA-directed DNA polymerase</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Integrase catalytic" evidence="7">
        <location>
            <begin position="190"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50994"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OBZ81002.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="487" mass="55145" checksum="861B8A2D60602C67" modified="2016-11-30" version="1" fragment="single">ALDYFHPYVHGANLTIYTDHAALKSILSTKLPKGRINRWIMALQSYQFAIIHKKGLLNLDADALSWLTQNNQEGLSAGDFKTLQQQDSEIIVLLREEVKLPFVWQNGVLGRTLEKGEVKPVISRMLVSTVLKQAHDGPVGGHFGVDKTLDKTKQIGWWSSQIQDVKTWVQHCEGCQSKKIRTESTAAPLKLICPSYLDEIWAADIAVLTKSKKGNRYLLVFMEYLSKWLITAAIPSLDTDQVVQVLLFEVVLKLGVPARLIADNGTNFVCEAVKQVCARLGIQRSLTSVEHPQTDGLVERLNRTIKTSLTICTEGNPLDWDEQLPFVTFAYNTAKQSSTRFSPFEVLFGRKARLPVLPDLELESAKSYETETWVAYLKNRIPLLHGQVVKNIEQAQVRQKRSYNKGSRVKYDYKTGDLIARKNLEKSGFPKERWSNPWTIVGPNNSEGTSFKIVKKNDPYRHVSTANVKHTRPWFSEQDRSSLVAKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MX59</accession>
    <name>A0A1C7MX59_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">CCHC-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">A0J61_10534</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001221">
        <property type="protein sequence ID" value="OBZ81417.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MX59"/>
    <dbReference type="InParanoid" id="A0A1C7MX59"/>
    <dbReference type="OrthoDB" id="2228125at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.10.10">
        <property type="entry name" value="Endonuclease/exonuclease/phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.60.10">
        <property type="entry name" value="Zinc finger, CCHC-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036691">
        <property type="entry name" value="Endo/exonu/phosph_ase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005135">
        <property type="entry name" value="Endo/exonuclease/phosphatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001878">
        <property type="entry name" value="Znf_CCHC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036875">
        <property type="entry name" value="Znf_CCHC_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03372">
        <property type="entry name" value="Exo_endo_phos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00098">
        <property type="entry name" value="zf-CCHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00343">
        <property type="entry name" value="ZnF_C2HC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56219">
        <property type="entry name" value="DNase I-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57756">
        <property type="entry name" value="Retrovirus zinc finger-like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50158">
        <property type="entry name" value="ZF_CCHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="CCHC-type" evidence="3">
        <location>
            <begin position="107"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="143"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="143"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="853"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OBZ81417.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="853" mass="96325" checksum="3248A33310D78F07" modified="2016-11-30" version="1" fragment="single">TLIKGYRSLPADAKIARVKVERLPLIHSLRLREQMVERFSHFGEVLDAGLHMDGSVFYGQGYVVLNLNKPHATEPQILSRIVDWGDKDRDLLLTWDEMPPFCLYRQCFNCNERGHISRDCPRRGHGLAHPPNKRVVVGQAKLDLPRPKVTAETKETSSSARTSSFKRRQPAVTASPAPSLAELTNRGQKRVGEAAKVIEEDHDGMEVYIEGSDDEATSVTMFEQQHSSEATHQMDEGNRMYEDALRHDDSSSSQPVKTNDSTKRSLFFRFLRSTQTDIFCFQETHAKTASSKSTLDMMLQSHSSLWNEHCGIVSFNPLYIAQPHGEIVASDARFILAFVGNTNNPTSPLMHILNIYAPATRQARLAFFRDLASNLSLMSLLHSLTTPIIIVGDFNYDLHQQNTIDSSWSKLLSGAFHDCFDHMRLPTFVSTTGSRSLLDYIFCSSTFSDNVVSMSHSFVNYSWTDHALLSISYRISCETMGKGSWKGNPFLAKLPSYREGLTSHIQNYVQSERLLDPHQQRSTQTIWDQLKAQVKQYTRSFQLNRLNWQKKSLKRLQSKRNRILRDYKNTAILSSLLPTVEALIGDLQSEIASIDQLKAGKSWRENGEKSAGYLKRIASSRTTQRMILTLHDPQTEKLVTTTEQKTRVVVDFYNSLYHPDRIHLNDVNALLDSLFSYADDTLVFLRDQHDLLRLRAHLDSYCQASNAKINLSKVRAISLSGRNLNDQWLPHLDHLGIHKIWNSSDTDPVIYLGYPLIQSITQRDTFFSSFIGSIATIAASHASRNLSVLGPATVANALILSKCWYILSVTPITKAILLSIQLVVSSFVSRGIFPRLSWVSMAAPRKHGGLGII</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-06-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MXG1</accession>
    <name>A0A1C7MXG1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_10356</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001132">
        <property type="protein sequence ID" value="OBZ81595.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MXG1"/>
    <dbReference type="InParanoid" id="A0A1C7MXG1"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ81595.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="117" mass="14034" checksum="B2BDB9139BE88631" modified="2016-11-30" version="1">MLRNISQNYWLTRHPTLLTKSFFIADPAQKRLRLEIKAEYTVFPRLCYTLFLDLLRRRRIQLFPFLWQYILHDIGPEVLDPPRISIQSQLTSHPLWTRFTSSGFTMHGFHDATNRSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MY42</accession>
    <name>A0A1C7MY42_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_10229</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001080">
        <property type="protein sequence ID" value="OBZ81722.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MY42"/>
    <dbReference type="InParanoid" id="A0A1C7MY42"/>
    <dbReference type="OrthoDB" id="2275770at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="188"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="193"/>
            <end position="215"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ81722.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="271" mass="31110" checksum="7925128143077CF9" modified="2016-11-30" version="1">MSATTEEGLRSPRRSQIDTADEGSAYFTFTPCTRLSRMAIDSQSIGLGRIRSSPQRQQLPVTNFNQKLMSVLREESNAHHPNLDMCLSSQGISMYDKSKDILSFSEDEDSDEGDLFSSSLCIMASPERPFTRESIFDDEMMLPTPTMPQINCSLFNEDDNEMMEQDDVYDPSNAWLSCIFHDTTYLHNNNNSHHKDNEEEVDKENRPPRIWRDNKQAPSTQSLRIPLSEIEDTDDLPTKKKMCVSQNGTTRKIRLMRTLSPPRFTSKQKDH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MYF7</accession>
    <name>A0A1C7MYF7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">SH3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">A0J61_11797</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01002507">
        <property type="protein sequence ID" value="OBZ80154.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MYF7"/>
    <dbReference type="STRING" id="101091.A0A1C7MYF7"/>
    <dbReference type="InParanoid" id="A0A1C7MYF7"/>
    <dbReference type="OrthoDB" id="10255964at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005085">
        <property type="term" value="F:guanyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd11883">
        <property type="entry name" value="SH3_Sdc25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.30.40:FF:000072">
        <property type="entry name" value="Unconventional Myosin IB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.40">
        <property type="entry name" value="SH3 Domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056685">
        <property type="entry name" value="DUF7783"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036028">
        <property type="entry name" value="SH3-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001452">
        <property type="entry name" value="SH3_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46026">
        <property type="entry name" value="RHO-TYPE GUANINE NUCLEOTIDE EXCHANGE FACTOR, ISOFORM F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46026:SF1">
        <property type="entry name" value="RHO-TYPE GUANINE NUCLEOTIDE EXCHANGE FACTOR, ISOFORM F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25006">
        <property type="entry name" value="DUF7783"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00018">
        <property type="entry name" value="SH3_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00499">
        <property type="entry name" value="P67PHOX"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00452">
        <property type="entry name" value="SH3DOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00326">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50044">
        <property type="entry name" value="SH3-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50002">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0728">SH3 domain</keyword>
    <feature type="domain" description="SH3" evidence="4">
        <location>
            <begin position="5"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="117"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="286"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OBZ80154.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="286" mass="32089" checksum="EA4DDC2E9959B680" modified="2016-11-30" version="1" fragment="single">MNSLSLLCTVQALYTFESNDPSSLRFEEGDFIDVLSKLSSGWWDGWCNGQRGWFPSNYVKIIKEYDGNTMVNQQSLFDDNVGETTSILNHKLPSQWITQLAPDGTHHYFNTSTGEIRTSWRPEESPSDACDLSEDENSTIDSYPKPDPIFTPDERPQDKKMIGATYFPLNQVQSSTEPSQHNDILDWEQMATHITTAIHQLVTAAKDGHHESYNKLASVIVDAVRSMLVSSGTMSRESIYLKNDSTLRSHHRTMMASMSKLVLSAQLCSDTSLAPDASKLLADCHE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MYN0</accession>
    <name>A0A1C7MYN0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">erg26_1</name>
        <name evidence="2" type="ORF">A0J61_10083</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001026">
        <property type="protein sequence ID" value="OBZ81868.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MYN0"/>
    <dbReference type="FunCoup" id="A0A1C7MYN0">
        <property type="interactions" value="177"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7MYN0"/>
    <dbReference type="InParanoid" id="A0A1C7MYN0"/>
    <dbReference type="OrthoDB" id="10058185at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016616">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006694">
        <property type="term" value="P:steroid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002225">
        <property type="entry name" value="3Beta_OHSteriod_DH/Estase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43000">
        <property type="entry name" value="DTDP-D-GLUCOSE 4,6-DEHYDRATASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01073">
        <property type="entry name" value="3Beta_HSD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="3-beta hydroxysteroid dehydrogenase/isomerase" evidence="1">
        <location>
            <begin position="6"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="307"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ81868.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="307" mass="33792" checksum="0D33A091641E98E5" modified="2016-11-30" version="1" fragment="single">MPASYLVIGGNGFLGQHIQEQIRLRNDGSTIAVFDISEPREPKPDVKYYTGDLRQFDDVYRALEGITAVVHAASPPHVNSSNPPRDLYFSINVDGTRNVIKACQERKIKVLVVTSSGSVISTGEPMVNIDESTPYPPKAVDVYTESKIECEKVVLAANGQQGLLTCTIRPSAIFGPGDRQMIPGMLEVCQRGQHRFQIGNNQSLMDFTYVGNVAYAHVLAAEKLAVPDSGAAGQAFNLTNGTPVPFWDFASRIWAVYGAYMPNNKKIVLSYNASMFIALISESILSIKQLFWDKSQLKEGMTRARIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MZ26</accession>
    <name>A0A1C7MZ26_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">GTP-binding protein 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">Gtpbp2</name>
        <name evidence="5" type="ORF">A0J61_09884</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000963">
        <property type="protein sequence ID" value="OBZ82067.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MZ26"/>
    <dbReference type="STRING" id="101091.A0A1C7MZ26"/>
    <dbReference type="InParanoid" id="A0A1C7MZ26"/>
    <dbReference type="OrthoDB" id="248233at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd03694">
        <property type="entry name" value="GTPBP_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.10">
        <property type="entry name" value="Translation factors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050055">
        <property type="entry name" value="EF-Tu_GTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000795">
        <property type="entry name" value="T_Tr_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009001">
        <property type="entry name" value="Transl_elong_EF1A/Init_IF2_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43721">
        <property type="entry name" value="ELONGATION FACTOR TU-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43721:SF9">
        <property type="entry name" value="GTP-BINDING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00009">
        <property type="entry name" value="GTP_EFTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50465">
        <property type="entry name" value="EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="Translation proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51722">
        <property type="entry name" value="G_TR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tr-type G" evidence="4">
        <location>
            <begin position="132"/>
            <end position="364"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OBZ82067.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="564" mass="62496" checksum="251E8353E1F5E8E0" modified="2016-11-30" version="1">MAVGSSLLTRCYPYGNLPPEVDDQGNIEYKLKLTNTSIERLEHLITQMKWRLSEGNGEAVYEIGIEDDGSIKGLTTEDMNTTIETLRTMATALEADISVMREFTLHHHTKSNLKVAEILVRRRPTDDQVQSFADLRIALVGGLGAGKSTLVSHLAHGAKDNGRGKARLNLLRHRHELESGRSSSISHEIIGYDSDGGLINYATTNVSTWEQICESSSKIITFLDTCGYPKYLRTTISGLVGYAPDYACLVIAGNAGTVADITREHLSIAVMIDVPVFVVITKSDIATPDQLRRTLHSLLTILKSPWMNKVPVVVQTEGDLVTCASHFARRGPEIPIFMVSNVTGSRIPLLQKFFHCLPKPTRLDYDTLLEEPVEFQIEEVYSLPDVGIVIGGLLSQGRVNVKEHQDYYLGPNAKGEFVKVNVVSIHRHRTPVRFVHCGQTATLAIEYPVPVDWKIHRGMVLLGTEDYPECYFEFEAELVVLFHATGVSCGTSGMIHSGSIRQHARVVSLLSDKESSVICSGGQGKCTFRLMHEPRYLRLGAQILFIEGKSKCLGRVTRLIPRVC</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N018</accession>
    <name>A0A1C7N018_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Mid2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">A0J61_09454</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000854">
        <property type="protein sequence ID" value="OBZ82495.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N018"/>
    <dbReference type="STRING" id="101091.A0A1C7N018"/>
    <dbReference type="InParanoid" id="A0A1C7N018"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008889388" description="Mid2 domain-containing protein" evidence="3">
        <location>
            <begin position="28"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="196"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="152"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="268"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="156"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="268"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="307"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OBZ82495.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="307" mass="32839" checksum="75337640C465FAAA" modified="2016-11-30" version="1" fragment="single">MTGEKKMKSNHLSLFVLGCLLSQDANAQFLCAVFGNCDSVSTVSEPIAASTSSVGSNSIVSSSAIKESIKSEPTSTFLQVPTQTTTTTTTTTTTAAAVATLTTNQFNTPFIGFPTQSLVYTTPLATFSDLFPTPSTIQTFNSNYYRETFGASSKASSSWNPTTTTSNMPSSSLSSTPSPSTVSKKTSDDSSSKKHIIIGAVCAAVAFLAAGFAYVFLTQRKKTRERTQRLSSMTNNELMQVGYDDYHTNGGSTADNNKTTTQNNPYSMSEPQAYNNNAMMSPQPPLPTANPTDPYYPSPQMAYNPND</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N0S8</accession>
    <name>A0A1C7N0S8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">coproporphyrinogen oxidase</fullName>
            <ecNumber evidence="4">1.3.3.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">CPOX</name>
        <name evidence="8" type="ORF">A0J61_09229</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Porphyrin-containing compound metabolism; protoporphyrin-IX biosynthesis; protoporphyrinogen-IX from coproporphyrinogen-III (O2 route): step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the aerobic coproporphyrinogen-III oxidase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.3.3.3" evidence="4"/>
    <dbReference type="EMBL" id="LUGH01000803">
        <property type="protein sequence ID" value="OBZ82720.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N0S8"/>
    <dbReference type="FunCoup" id="A0A1C7N0S8">
        <property type="interactions" value="375"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N0S8"/>
    <dbReference type="InParanoid" id="A0A1C7N0S8"/>
    <dbReference type="OrthoDB" id="15318at2759"/>
    <dbReference type="UniPathway" id="UPA00251">
        <property type="reaction ID" value="UER00322"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004109">
        <property type="term" value="F:coproporphyrinogen oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006782">
        <property type="term" value="P:protoporphyrinogen IX biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.1500.10:FF:000002">
        <property type="entry name" value="oxygen-dependent coproporphyrinogen-III oxidase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1500.10">
        <property type="entry name" value="Coproporphyrinogen III oxidase, aerobic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001260">
        <property type="entry name" value="Coprogen_oxidase_aer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036406">
        <property type="entry name" value="Coprogen_oxidase_aer_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003727">
        <property type="entry name" value="PRK05330.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10755">
        <property type="entry name" value="COPROPORPHYRINOGEN III OXIDASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10755:SF0">
        <property type="entry name" value="OXYGEN-DEPENDENT COPROPORPHYRINOGEN-III OXIDASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01218">
        <property type="entry name" value="Coprogen_oxidas"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000166">
        <property type="entry name" value="Coproporphyri_ox"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00073">
        <property type="entry name" value="COPRGNOXDASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102886">
        <property type="entry name" value="Coproporphyrinogen III oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0350">Heme biosynthesis</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-0627">Porphyrin biosynthesis</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005168"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010644"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012869"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OBZ82720.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="308" mass="35382" checksum="132BD668932D9E35" modified="2016-11-30" version="1">MEAFVKDLQDRICSTIEAVDGQGKFTRTVWERSEHGGEGITAVMSDGTVMEKAGVAVSVVYSELTPEAIRQMRQDRGKEIEDTNGTVPFFVTGISLVMHAKNPNAPTVHMNYRYFEVMNSDGTPKLWWFGGGADLTPVYLFEEDAKFFHQVYQEGCNKFDPSYYPKMKKACDLYFLNKHRQEARGIGGIFFDDFNSAPAEDIFEFVQEMGNRFLPSYVPILEKRKDMPFTTEMVDWQQIRRGRYVEFNLIWDRGTKFGLATPCARVESILMTMPLTARWEYMHEPKKGSPEAALVEVLQNPRDWAHCD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N121</accession>
    <name>A0A1C7N121_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">A0J61_09574</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000882">
        <property type="protein sequence ID" value="OBZ82376.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N121"/>
    <dbReference type="STRING" id="101091.A0A1C7N121"/>
    <dbReference type="InParanoid" id="A0A1C7N121"/>
    <dbReference type="OrthoDB" id="3269380at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051580">
        <property type="entry name" value="ZnF-Chromatin_assoc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23057">
        <property type="entry name" value="JUXTAPOSED WITH ANOTHER ZINC FINGER PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23057:SF0">
        <property type="entry name" value="JUXTAPOSED WITH ANOTHER ZINC FINGER PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="5">
        <location>
            <begin position="96"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="154"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS00028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OBZ82376.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="154" mass="16322" checksum="F29A8C1E30CBB385" modified="2016-11-30" version="1" fragment="single">MLIHIASKVDSNPEQLEYKLALEHYTRNHSAITTTQPATIASAVGSPPSPTPNQAMSLAEAAVAAAAAAAASATPSNATPSSEFDGYGNGFKPYGCDVPGCYTAFAASTDLFCHMKSCHPNLEGVDKPYRCALINCQKKYKNINGLQYHIKDAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-06-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N195</accession>
    <name>A0A1C7N195_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_10817</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001417">
        <property type="protein sequence ID" value="OBZ81134.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N195"/>
    <dbReference type="InParanoid" id="A0A1C7N195"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ81134.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="55" mass="6236" checksum="13BC55D1EF0670F4" modified="2016-11-30" version="1" fragment="single">MPQLWGKFENHSLNQDVKIADVSIKDVEAAVKRYFGKLPNGVARLENNQVRLAAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N1Q3</accession>
    <name>A0A1C7N1Q3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">BZIP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">A0J61_08961</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000744">
        <property type="protein sequence ID" value="OBZ82987.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N1Q3"/>
    <dbReference type="STRING" id="101091.A0A1C7N1Q3"/>
    <dbReference type="InParanoid" id="A0A1C7N1Q3"/>
    <dbReference type="OrthoDB" id="5571888at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd14810">
        <property type="entry name" value="bZIP_u1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.170">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004827">
        <property type="entry name" value="bZIP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046347">
        <property type="entry name" value="bZIP_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051027">
        <property type="entry name" value="bZIP_transcription_factors"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19304">
        <property type="entry name" value="CYCLIC-AMP RESPONSE ELEMENT BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00170">
        <property type="entry name" value="bZIP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00338">
        <property type="entry name" value="BRLZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57959">
        <property type="entry name" value="Leucine zipper domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50217">
        <property type="entry name" value="BZIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00036">
        <property type="entry name" value="BZIP_BASIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="BZIP" evidence="7">
        <location>
            <begin position="234"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="149"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="298"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="462"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="529"/>
            <end position="560"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="259"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="149"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="164"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="222"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="305"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="466"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="529"/>
            <end position="547"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OBZ82987.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="624" mass="70878" checksum="9FE3F09CDAB9D321" modified="2016-11-30" version="1">MEPMSFDWLDNDNDILDSLVQLASLPNQPISPDNVSHINTNNDILHYLNQQANTQQQHNMNSTSSGSFLMQGGFAFEPSVTHNLPSRQQEMSPEKVNQVIESIGRIDPAATGGVPPKFNEAEVSAVFQQPISIVQGNDNFVTFTPVLSKSGDSATADTNSNGHRNTKSKQTAKKVKYREPIFVTESPQSFNKKMKKYPANNTNNTHQSSSAEENSEDEDETMLQNTNSSSLKQMSSKERRQLRNKISARNFRVRRKEYITKLEEKVEQQEKIIQSLREENAKLRKANQEVMNQVLDQLITPPPSSDEFQSSSPSSSSEGHGSPYGPAPIQQFQFNDLYSFDLFDQHPAQPLPETSNAFYLNHAVMPDWDMQRVLSDKMVSETTDEHKKELVRDLFANYPLLAPALMSIVIRHTLSLEYVANLMREFTESIENDNATVYGRSEDEETLRGHDDLEDLKASMNAMNINEDKVKEETPSPKEKQDELDDQAHLEIMLKSCFVSYALQRARGLSHQQAFDRYKQCAKHHPEWIEKIKKQSKKTKETKDSKKAGSSKKSSKKSSGIQTLQAYCRVAGTLLRQPQRMTNVGQVLKEQIQFTSNKHISVIEHNFRKSINSSRPQNFRIANC</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N1W6</accession>
    <name>A0A1C7N1W6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">RNA helicase</fullName>
            <ecNumber evidence="2">3.6.4.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">RH24</name>
        <name evidence="14" type="ORF">A0J61_08974</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the DEAD box helicase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.13" evidence="2"/>
    <dbReference type="EMBL" id="LUGH01000746">
        <property type="protein sequence ID" value="OBZ82978.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N1W6"/>
    <dbReference type="STRING" id="101091.A0A1C7N1W6"/>
    <dbReference type="InParanoid" id="A0A1C7N1W6"/>
    <dbReference type="OrthoDB" id="196131at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd18787">
        <property type="entry name" value="SF2_C_DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000079">
        <property type="entry name" value="probable ATP-dependent RNA helicase DDX17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000629">
        <property type="entry name" value="RNA-helicase_DEAD-box_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014014">
        <property type="entry name" value="RNA_helicase_DEAD_Q_motif"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47958">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE DBP3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00039">
        <property type="entry name" value="DEAD_ATP_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51195">
        <property type="entry name" value="Q_MOTIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 9 14" id="KW-0347">Helicase</keyword>
    <keyword evidence="4 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DEAD-box RNA helicase Q" evidence="13">
        <location>
            <begin position="227"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="11">
        <location>
            <begin position="258"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="12">
        <location>
            <begin position="463"/>
            <end position="607"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="616"/>
            <end position="666"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Q motif" evidence="8">
        <location>
            <begin position="227"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="20"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="92"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="10">
        <location>
            <begin position="616"/>
            <end position="631"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU000492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="OBZ82978.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="666" mass="74464" checksum="058873DB2A44DAB1" modified="2016-11-30" version="1">MFQQKGGPKKFNFGFPSKKTTKEDPSKRKTTETSEEPKKRQRPAFVDDDQDELLAIAGIANLPQETPTEQKQEEEDDDPLDAFMADMSEQAKSTKTEPKIRRDDIEDEDDLESYVRHMKEKGVTVGNTNQPLPEYDENANSDDEVYATAAAIDARLDELDEDATEPIKKEIEPLARINHDTMDYIDIEKNFYQEHPDIAALDPDRVRAIRQELGLHVSGHDAVKPCISFGHFGFDEDLMNAVIKAGYTEPSAIQKQAIPVALSGRDIIGIAKTGSGKTAAFVLPMLVHIMDQQELVKGDGPIGLILAPTRELAIQIYQESRKFAKAYGLKVAAVYGGASKLEQFKDLRSGTVEILVATPGRLIDMIKMKATNLKRVSYLVLDEADRMFDLGFEPQVRSVCDNVRPDRQTLLFSATFQKRIEALARNVTSDPVRINVGTTGQANEDITQIVQVFEQDDQKWDWLIHHLTGFCIEGSVIIFVGRKDAVDMLSSNLNAANFECVALHGDLQQFEREKVLRDFKTNKVKILVSTDVAARGLDIKTVKTVVNYDVARDIDSHTHRVGRTGRAGEKGRAYTLITEKEDRFAGELVRHLETSGQMAPPELLGLAMRNPRFRDARHHRGRGRGRGRGRGNARGNANMEPIKFQRSSTGGLGTDASRPPKPSRWQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N2K2</accession>
    <name>A0A1C7N2K2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Pleckstrin y domain-containing family A member 8</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">PLEKHA8_0</name>
        <name evidence="3" type="ORF">A0J61_10366</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001138">
        <property type="protein sequence ID" value="OBZ81584.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N2K2"/>
    <dbReference type="STRING" id="101091.A0A1C7N2K2"/>
    <dbReference type="InParanoid" id="A0A1C7N2K2"/>
    <dbReference type="OrthoDB" id="205255at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902387">
        <property type="term" value="F:ceramide 1-phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902388">
        <property type="term" value="F:ceramide 1-phosphate transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.3520.10:FF:000001">
        <property type="entry name" value="Pleckstrin domain-containing family A member 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3520.10">
        <property type="entry name" value="Glycolipid transfer protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036497">
        <property type="entry name" value="GLTP_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014830">
        <property type="entry name" value="Glycolipid_transfer_prot_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10219">
        <property type="entry name" value="GLYCOLIPID TRANSFER PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10219:SF25">
        <property type="entry name" value="PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY A MEMBER 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08718">
        <property type="entry name" value="GLTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110004">
        <property type="entry name" value="Glycolipid transfer protein, GLTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Glycolipid transfer protein" evidence="2">
        <location>
            <begin position="20"/>
            <end position="158"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF08718"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ81584.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="196" mass="22276" checksum="BCB42ADEA6B660EF" modified="2016-11-30" version="1">MTYFDTLQRSYVDVDISNGINTEQFLEATEGLVKLFDLLGSSAFAVVQKDMNGNIKKIRDRYLTNPTANATLQSLMATEAPEKKRVATEGLLWLTRGLDFTAQALRRSIDNGSEELAASFTQSYEDTLKKHHSMFVRPVFGLAMKACPYREDFYKKIGVQDEAGQTQMRQWLEALENIIRIIQEVFTDNPAYIKGM</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N2M6</accession>
    <name>A0A1C7N2M6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">sn-1-specific diacylglycerol lipase</fullName>
            <ecNumber evidence="14">3.1.1.116</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="primary">Dagla_0</name>
        <name evidence="17" type="ORF">A0J61_08679</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>a 1,2-diacyl-sn-glycerol + H2O = a 2-acylglycerol + a fatty acid + H(+)</text>
            <dbReference type="Rhea" id="RHEA:33275"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17389"/>
            <dbReference type="ChEBI" id="CHEBI:17815"/>
            <dbReference type="ChEBI" id="CHEBI:28868"/>
            <dbReference type="EC" id="3.1.1.116"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="13">
            <dbReference type="Rhea" id="RHEA:33276"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.116" evidence="14"/>
    <dbReference type="EMBL" id="LUGH01000692">
        <property type="protein sequence ID" value="OBZ83271.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N2M6"/>
    <dbReference type="InParanoid" id="A0A1C7N2M6"/>
    <dbReference type="OrthoDB" id="438440at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016298">
        <property type="term" value="F:lipase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019369">
        <property type="term" value="P:arachidonate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046340">
        <property type="term" value="P:diacylglycerol catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00030">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00519">
        <property type="entry name" value="Lipase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.150">
        <property type="entry name" value="C2 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000008">
        <property type="entry name" value="C2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035892">
        <property type="entry name" value="C2_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052214">
        <property type="entry name" value="DAG_Lipase-Related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002921">
        <property type="entry name" value="Fungal_lipase-type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45792">
        <property type="entry name" value="DIACYLGLYCEROL LIPASE HOMOLOG-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45792:SF8">
        <property type="entry name" value="DIACYLGLYCEROL LIPASE-ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00168">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01764">
        <property type="entry name" value="Lipase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49562">
        <property type="entry name" value="C2 domain (Calcium/lipid-binding domain, CaLB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50004">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-0106">Calcium</keyword>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-0442">Lipid degradation</keyword>
    <keyword evidence="11" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="12" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="C2" evidence="16">
        <location>
            <begin position="3"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="228"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="749"/>
            <end position="807"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="15">
        <location>
            <begin position="228"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="15">
        <location>
            <begin position="240"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="15">
        <location>
            <begin position="766"/>
            <end position="778"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022963"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00024531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00026104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="OBZ83271.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="807" mass="91127" checksum="EB3C7811E5E80052" modified="2016-11-30" version="1">MNDITQRRSSSARSIATLPPGKLRITIKNCFLNIPIKKPYITITLGDQYHKTSISEYPEGAWNEGFELKITYHNQLFDTIQLDLYDSNTFFIDKHIGRAEIRLRNLESMPDVFTSYYEVFEKKLSMGATSQVSRKMTSGVGAIQAEIAYHYRSSLKQHSNDGDHLSPAVEFSEMNWLIDQQQRALSSNSLDNIDVSAQQDSRAVDLEMIAEFNRDLKSQRDNEDIEFQKIEQNSRHHDTDEDYPDDSTEDEVEEELDEKQEDGSTAGKATRQPLTYSVSRASSTFKADASLTEKKDDQSGGFLETVSSFFGYSAPKTNHNQTEKNQLLTPDDDTLKSFPLLDTIGSWTMAKETNQVFRAIGKIIVAFGQGFELSNLQILSGFNVVEKFYNDLPRERTWDLVEDISEIEMASYMWRYAIASYGWKGLNFIGKGNGYISDAVRSQSDALSICEHLGIPKEDLLAYELRTGAAFRPSYYIARDRKLNAIVLSIRGTMSTFDTMTDLVCEYEPWKGGLVHKGMKVGNIRSSANWFFRNIAPKLIAYVNKHSTTSLYIVGHSLGASTAAILTIMLQDFIKEFRKGKDKNFSIYSFGYAPACGLSLNLANQYKDQIQSIVFADDFVSKLSYGSMMDVKELIIAGAEAAKDLGFGQLIWPTEVDSEAWKKAFEKIAECRKRCLESMSNPRLYVAGKVYQFWLDPTPNNESRIVVERTTPERVSTELIIRMSIVLDHLPTNFDVAFKRALESLKTAKREGKDEITDENNAVSLEDNKKKPSARDNIYESVAEIGLKGTTERKGGEGNVLGQSEAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N2U3</accession>
    <name>A0A1C7N2U3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_09010</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000754">
        <property type="protein sequence ID" value="OBZ82939.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N2U3"/>
    <dbReference type="InParanoid" id="A0A1C7N2U3"/>
    <dbReference type="OrthoDB" id="2286253at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="68"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="48"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ82939.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="125" mass="14026" checksum="6CFD2D96F268B0C6" modified="2016-11-30" version="1">MNNPPPPAYHQNQKPGETYYAPPSQPPPENSNYAPPSQPPPPYQNIGQRVTHFYAPPQNKRLGIKRRMCSFICCCILIGLIVGLAAGLTRRSYYSRGCNCRTSSDCVYQFGAGTYCYRSCQCARR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N2W7</accession>
    <name>A0A1C7N2W7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_08506</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000662">
        <property type="protein sequence ID" value="OBZ83442.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N2W7"/>
    <dbReference type="InParanoid" id="A0A1C7N2W7"/>
    <dbReference type="OrthoDB" id="2286861at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="31"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="9"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="31"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="48"/>
            <end position="69"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ83442.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="146" mass="16410" checksum="D71977124410EE1C" modified="2016-11-30" version="1">MSLFRKSTDQSSLKINTNPFETSRVRQRFSSWFRSSPTSPKGSKRNSPTPVTPTLVHHPSSASLSSLSDVSDHMPASPVDNQPTLWQKQPEDYQHNVLSLADQVRLVLGSALDEVDEEIEGDWEQSRAVLQQSLVLPTKERISLRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N3D7</accession>
    <name>A0A1C7N3D7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Zinc-regulated transporter 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">ZRT2_0</name>
        <name evidence="11" type="ORF">A0J61_08306</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 8">Membrane</location>
            <topology evidence="1 8">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the ZIP transporter (TC 2.A.5) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000627">
        <property type="protein sequence ID" value="OBZ83645.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N3D7"/>
    <dbReference type="FunCoup" id="A0A1C7N3D7">
        <property type="interactions" value="304"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N3D7"/>
    <dbReference type="InParanoid" id="A0A1C7N3D7"/>
    <dbReference type="OrthoDB" id="448280at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000007">
        <property type="term" value="F:low-affinity zinc ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071578">
        <property type="term" value="P:zinc ion import across plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003689">
        <property type="entry name" value="ZIP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004698">
        <property type="entry name" value="Zn/Fe_permease_fun/pln"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00820">
        <property type="entry name" value="zip"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11040:SF44">
        <property type="entry name" value="PROTEIN ZNTC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11040">
        <property type="entry name" value="ZINC/IRON TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02535">
        <property type="entry name" value="Zip"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0406">Ion transport</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0732">Signal</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 8" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="10">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008889468" evidence="10">
        <location>
            <begin position="21"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="44"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="81"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="123"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="217"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="242"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="276"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="308"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="350"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="163"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="163"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="173"/>
            <end position="183"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006939"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU362088"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="OBZ83645.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="370" mass="40093" checksum="0D0E23F4C7CEC2A9" modified="2016-11-30" version="1">MSTHSVLYALLLSSLSAVMAQDVSTEAAPEEDECASPSMADYNLPLRVGALFIILGTSALGVFAPIVLHKISPYTKNSIRGWILTIGKFFGTGVILATAFVHMLPEALENFDSDCLSDGWKSYGAFAGVFCMLSSFALQLLELAAVANIERIREKKAAEIMTADMEKSERASDNSLDTSATANQNTSHDVCHDHAHEHVHSAGLFEEEDAYKHIGTLILELGIVMHSIIIGITLSNTGSDEFVTLLIALVFHQFFEGVALGTRINEMNIKGWARPALMGTLFMIMTPIGCAIGIGIHSSFNPNSSSSILASAILDSLSAGILLYNAYISLMSQEINHNADFRRIPFMRKFVCFVSMYLGAGLMALLGKWA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N3J1</accession>
    <name>A0A1C7N3J1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_08748</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000703">
        <property type="protein sequence ID" value="OBZ83206.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N3J1"/>
    <dbReference type="InParanoid" id="A0A1C7N3J1"/>
    <dbReference type="OrthoDB" id="29657at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009637">
        <property type="entry name" value="GPR107/GPR108-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21229">
        <property type="entry name" value="LUNG SEVEN TRANSMEMBRANE RECEPTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21229:SF2">
        <property type="entry name" value="RE59932P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008889471" evidence="2">
        <location>
            <begin position="22"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="177"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="211"/>
            <end position="229"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ83206.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="233" mass="26685" checksum="74098FC1D6B79A06" modified="2016-11-30" version="1">MYISLLRRVWLWLLLLRVVVAVPKLVVENDDRKVVDVAEFGFLPNGRLSLNLTHLKWQDPSKPGTGAFYIRKGRAVQDEYVSLPEEEQSLPIHYDTRCFLNESLIADEVNDGTSIVRYLPEHTSELQETFYVKEGEEGIWQVLFVSCKDSAVSYELLIEQINPNGNYLSAGDIPLPYVYMVSSAAYVTATLYWLSLLVLKRNQSQVFRAHWLMLVLLLCIIINKSLQSVKSSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N3T7</accession>
    <name>A0A1C7N3T7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_08648</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000687">
        <property type="protein sequence ID" value="OBZ83299.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N3T7"/>
    <dbReference type="STRING" id="101091.A0A1C7N3T7"/>
    <dbReference type="InParanoid" id="A0A1C7N3T7"/>
    <dbReference type="OrthoDB" id="2287217at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="91"/>
            <end position="118"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ83299.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="129" mass="13579" checksum="6CE37BCD231FA54F" modified="2016-11-30" version="1">MTTKKSTATTKKSTTSTKKSTTSTKKSTTSTKKSTMTTKKSTTATKKSTTTIKKPTMTTKKSTTTIKKSTTATKKPTTTIKKSTITVKSSATSSCIPGYSGKKKGNGPKSACCSSKSDCKDSCVKEKCT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N4L7</accession>
    <name>A0A1C7N4L7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_08347</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000633">
        <property type="protein sequence ID" value="OBZ83606.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N4L7"/>
    <dbReference type="InParanoid" id="A0A1C7N4L7"/>
    <dbReference type="OrthoDB" id="2240336at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ83606.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="544" mass="62442" checksum="26314F32C38D3ED2" modified="2016-11-30" version="1">MSDQNYTSKAEKQGRPNLHSLRGDYFIPEPVKKKFGLETLLKTNAAFWTNPEALIDAYFVNCLTWEPSCEKFFEALSSGLRRFSNSDSETLKARSYAQEVSSFIISKAVVNKVKVYYQLMAAKAESKRQEVLAKIHGEAAGAAFVSVGANNLRKRALDQLFAEEEIQDDPPQNKAAASTPKTTKETSFVINKGGHSYQLHTPVKEFLHSPQKPIIEDTDRLACSKYFDLRLSTDTVSRCSDGLEREYQDHIRKMRINSSLVLVLGDNYAEFIKHLFDVNMSNFSQEIFNIDHSSYVTAANSTFINFLKQSYNDLCICWSDTQDYQQSGERTLFSEVYLQQFKLFAKMTKLLYFKWIEKKMNNTDHVWLAKKNYVKKDVQLKLLDGTGIMKKNGVNFLMIESSGISSVGDDIYTHTLEDTIKNLKHGSDSLASILCDYQYCDINTTQKLVVLTCQIIKNKLTIMKYSPGNLSRWIAVEVRSCTIPLSYENRKDSIKLYEAFAYIYSTLREQIKVYDKLADERLGFTIVEEKNMVRNCNYFFEVDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N4Y2</accession>
    <name>A0A1C7N4Y2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Fe2OG dioxygenase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">A0J61_07778</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>L-ascorbate</name>
            <dbReference type="ChEBI" id="CHEBI:38290"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000546">
        <property type="protein sequence ID" value="OBZ84172.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N4Y2"/>
    <dbReference type="STRING" id="101091.A0A1C7N4Y2"/>
    <dbReference type="InParanoid" id="A0A1C7N4Y2"/>
    <dbReference type="OrthoDB" id="69177at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051213">
        <property type="term" value="F:dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031418">
        <property type="term" value="F:L-ascorbic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.620">
        <property type="entry name" value="q2cbj1_9rhob like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005123">
        <property type="entry name" value="Oxoglu/Fe-dep_dioxygenase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006620">
        <property type="entry name" value="Pro_4_hyd_alph"/>
    </dbReference>
    <dbReference type="SMART" id="SM00702">
        <property type="entry name" value="P4Hc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51471">
        <property type="entry name" value="FE2OG_OXY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="5" id="KW-0408">Iron</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fe2OG dioxygenase" evidence="7">
        <location>
            <begin position="136"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="18"/>
            <end position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001961"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OBZ84172.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="235" mass="27154" checksum="90D2E0ACD9BBCDCD" modified="2016-11-30" version="1">MSDEFDLFGETTEEEQARLNQLHDQSRSTTQTRLDSFPSDPNRRSQEDNRWIFHQLRRDRFQEPKIQPAVLSPEECQSILKTVSDQVWTGSRHSAFATTDIPIRSHPTLHYLVPLIKTRMFPQLAEYYGFKVTDIDFRDIFLVKYDTATQRGLEIHSDGCLFSLTLLISHPDDFEGGGTYYANMDRILYLKQGDCAHHNAHLMHSGVDITKGTRYILVGFIDTVDTVLKDSQLKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N583</accession>
    <name>A0A1C7N583_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_08132</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000599">
        <property type="protein sequence ID" value="OBZ83819.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N583"/>
    <dbReference type="STRING" id="101091.A0A1C7N583"/>
    <dbReference type="InParanoid" id="A0A1C7N583"/>
    <dbReference type="OrthoDB" id="3238634at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ83819.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="307" mass="35733" checksum="B22477819E0453BD" modified="2016-11-30" version="1">MEPSTLPEELVLATNTQHCKGPDCIANRGSMDCVCSHCGALIRAGRYSFEAFHFYHRDAQNTLASAMREIINQNQELHGFEDFFFLTYTFGDKYRLDLNNYDQQIRLHFNDLNFRLFDLQNTFIDIGLQLSSPGTTGIWILDQQTSPLLPLFFTVLNRSSRYLRLDVFANNANLGRCSYTTHRIEGNGRYHLMKFQCYQLLKSLFYLRTESGYRHNAFDLEPHHYLQNPARVLQNFESLVTALQQSRTRTFPARAEFTLRYDDGLRLLNNAQEEVMQILSQQPPVMTVLSTDIVVDYLVNIVNCYYQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N5W2</accession>
    <name>A0A1C7N5W2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">BZIP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">A0J61_07415</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000499">
        <property type="protein sequence ID" value="OBZ84535.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N5W2"/>
    <dbReference type="STRING" id="101091.A0A1C7N5W2"/>
    <dbReference type="InParanoid" id="A0A1C7N5W2"/>
    <dbReference type="OrthoDB" id="2257100at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12193">
        <property type="entry name" value="bZIP_GCN4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004827">
        <property type="entry name" value="bZIP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046347">
        <property type="entry name" value="bZIP_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031106">
        <property type="entry name" value="C/EBP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23334:SF20">
        <property type="entry name" value="BASIC LEUCINE ZIPPER 24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23334">
        <property type="entry name" value="CCAAT/ENHANCER BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07716">
        <property type="entry name" value="bZIP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00338">
        <property type="entry name" value="BRLZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57959">
        <property type="entry name" value="Leucine zipper domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50217">
        <property type="entry name" value="BZIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00036">
        <property type="entry name" value="BZIP_BASIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BZIP" evidence="3">
        <location>
            <begin position="152"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="125"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="177"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="145"/>
            <end position="167"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OBZ84535.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="237" mass="26500" checksum="4DBA8BCCE65D34F9" modified="2016-11-30" version="1">MNPVINHQLTYPFLVTGYDAQLNQAYTPPQQPNSPDPLTVNDWLNQLIVNPDLMVKEETPDFNHLFQFLPISPPLTTSPGSVHQDMTTSHDPLVALFPDILNTNLPPPRPVVVPRKTVPIMPKTSNVVPIAPRPGGFTPPITNKRKSENVESDEAAQKRQKNTDAARRSRLKKIIKMETLEKQVTELESDNARLTTRVAVLESEKSALVSKDKDLEERIRVLEAQLAEAHRALTTTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N6Q4</accession>
    <name>A0A1C7N6Q4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11, mitochondrial</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="15">Complex I-ESSS</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="14">NADH-ubiquinone oxidoreductase ESSS subunit</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">A0J61_07112</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18 19">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.</text>
    </comment>
    <comment type="subunit">
        <text evidence="16">Complex I is composed of 45 different subunits. Interacts with BCAP31.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion inner membrane</location>
            <topology evidence="2">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the complex I NDUFB11 subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000463">
        <property type="protein sequence ID" value="OBZ84835.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N6Q4"/>
    <dbReference type="STRING" id="101091.A0A1C7N6Q4"/>
    <dbReference type="InParanoid" id="A0A1C7N6Q4"/>
    <dbReference type="OrthoDB" id="2147978at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019329">
        <property type="entry name" value="NADH_UbQ_OxRdtase_ESSS_su"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40637">
        <property type="entry name" value="ESSS SUBUNIT OF NADH:UBIQUINONE OXIDOREDUCTASE (COMPLEX I) PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40637:SF1">
        <property type="entry name" value="ESSS SUBUNIT OF NADH:UBIQUINONE OXIDOREDUCTASE (COMPLEX I) PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10183">
        <property type="entry name" value="ESSS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0249">Electron transport</keyword>
    <keyword evidence="13 17" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="8" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0679">Respiratory chain</keyword>
    <keyword evidence="9" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="7 17" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="11 17" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="50"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008915"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00018632"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022660"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00030753"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00031387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00046528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="OBZ84835.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="99" mass="11133" checksum="3E13879DD86127DF" modified="2016-11-30" version="1">MIAQVLARSTRLARPTNMLRRGGHGPVSYNEPGGYLFNEKVRVKEDWENLYYAGMGGGFLLMAVALYYKPDTSVVTWAKKEAEKSLKEKGVNLEYTKTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N6T4</accession>
    <name>A0A1C7N6T4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Hexose transporter 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">KHT2_2</name>
        <name evidence="10" type="ORF">A0J61_07075</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000460">
        <property type="protein sequence ID" value="OBZ84875.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N6T4"/>
    <dbReference type="FunCoup" id="A0A1C7N6T4">
        <property type="interactions" value="330"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N6T4"/>
    <dbReference type="InParanoid" id="A0A1C7N6T4"/>
    <dbReference type="OrthoDB" id="4142200at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005351">
        <property type="term" value="F:carbohydrate:proton symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000134">
        <property type="entry name" value="MFS sugar transporter protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050360">
        <property type="entry name" value="MFS_Sugar_Transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00879">
        <property type="entry name" value="SP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022:SF2">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00171">
        <property type="entry name" value="SUGRTRNSPORT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00216">
        <property type="entry name" value="SUGAR_TRANSPORT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00217">
        <property type="entry name" value="SUGAR_TRANSPORT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="30"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="72"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="104"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="129"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="162"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="193"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="281"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="314"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="346"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="389"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="424"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="453"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="9">
        <location>
            <begin position="34"/>
            <end position="477"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OBZ84875.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="490" mass="53977" checksum="552078519F61E36C" modified="2016-11-30" version="1">MIQKHIKEESHYDAESIATKRTVHRNSRKSLYMSGIIAAGGGFVVGFDTGAVSGTMILEPFVNRFLQVDATYRSALLVAMMLLTATIGGLWSGSICDWIGRKNTILLGTGVFAIGALFETIGYNFGLLLAGRLLVGFGEGFLTNAIPLYHTEIAPPDIRGRLITLFSAMSSIGTIVGYFVNFGTSYLTTDWSWRTPFMVQLGVCLFLMLAYFLPFSPRWLIDKGRKEEALQVLAQLHGSSVDDPEVRNEFNCICEEIEQEHAYGNRTFVECFRGTNLKRTLFALFTGNGAAFTGTYSITYYAPQIFQQAGLNDIGVSLVASGASNVLVLIVTIVTLVVIDKLGRRGVFASGAFLMGASMYIVGGLFQGYNMEDSEGNVYLSNQHARNGAIAFIFIFQAAYAYSWGPVAYIYPAEIANMRMRAKTIALAYGLNWAIGIFMTFVLPIFMTNTIYGGYYFFGGCCTVLFLGSFFLPETKGKTLEEIDRIFNPI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N6X8</accession>
    <name>A0A1C7N6X8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_07074</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000459">
        <property type="protein sequence ID" value="OBZ84880.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N6X8"/>
    <dbReference type="InParanoid" id="A0A1C7N6X8"/>
    <dbReference type="OrthoDB" id="2324139at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008889518" evidence="1">
        <location>
            <begin position="20"/>
            <end position="263"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ84880.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="263" mass="29479" checksum="873E40E89A15AE9B" modified="2016-11-30" version="1">MLFKSIPVLLLAAASTALACEMDCRRGVSKGFAHFYGPVIEESVNNLQLKLTDAASKVSVPSIITQNIDSSEVTADLENSIKYSLDNFTTMATADSRLAEGFYQVIFNEELPYKGDCNNPKRLTRKMPPPGESWTMDECRKMDYRCGNPPSICYALEDVKQRCIGRMRRQMIDYSSPETGALVRSLVLGVRKSVHGSLQKGAAGKLIDNAEVGNYITKLVAVINRDLSDWVNEDVRQLCDKPSQKELCNSWDDDIRKEILRWP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N7H8</accession>
    <name>A0A1C7N7H8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Meiotic coiled-coil protein 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">mcp2</name>
        <name evidence="6" type="ORF">A0J61_08667</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000690">
        <property type="protein sequence ID" value="OBZ83284.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N7H8"/>
    <dbReference type="FunCoup" id="A0A1C7N7H8">
        <property type="interactions" value="352"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N7H8"/>
    <dbReference type="InParanoid" id="A0A1C7N7H8"/>
    <dbReference type="OrthoDB" id="668540at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003730">
        <property type="term" value="F:mRNA 3'-UTR binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010608">
        <property type="term" value="P:post-transcriptional regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07920">
        <property type="entry name" value="Pumilio"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033133">
        <property type="entry name" value="PUM-HD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033712">
        <property type="entry name" value="Pumilio_RNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001313">
        <property type="entry name" value="Pumilio_RNA-bd_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12537:SF48">
        <property type="entry name" value="MEIOTIC COILED-COIL PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12537">
        <property type="entry name" value="RNA BINDING PROTEIN PUMILIO-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00806">
        <property type="entry name" value="PUF"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="SMART" id="SM00025">
        <property type="entry name" value="Pumilio"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50302">
        <property type="entry name" value="PUM"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50303">
        <property type="entry name" value="PUM_HD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="PUM-HD" evidence="5">
        <location>
            <begin position="252"/>
            <end position="610"/>
        </location>
    </feature>
    <feature type="repeat" description="Pumilio" evidence="2">
        <location>
            <begin position="318"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="repeat" description="Pumilio" evidence="2">
        <location>
            <begin position="354"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="repeat" description="Pumilio" evidence="2">
        <location>
            <begin position="430"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="repeat" description="Pumilio" evidence="2">
        <location>
            <begin position="467"/>
            <end position="503"/>
        </location>
    </feature>
    <feature type="repeat" description="Pumilio" evidence="2">
        <location>
            <begin position="504"/>
            <end position="539"/>
        </location>
    </feature>
    <feature type="repeat" description="Pumilio" evidence="2">
        <location>
            <begin position="549"/>
            <end position="584"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="140"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="8"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OBZ83284.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="621" mass="71575" checksum="2ADAB8AB2A596585" modified="2016-11-30" version="1">MLAANSKPLSTSTSTTTDTDLTNLNPTYESLFYTPSSFFIPNPPTRHEEKNTIEGFSASSSDSFFQTLVNLEESPGTYLTKNDFQFDLAFARQYQGSSLKSNHSPASYATKLSYTQEQSPHNYPLYMNDMYQQQQIMHDSYTYQQQLKEANQLIQKLANQLSLMNIEMEKKTAHFQTALEAKEKKLKEQEQKLIMTNHLYESQTKRLNELLGMNRLCVEESSDHDPGVFKYSLDTMTAMHDRSETIDNIAHCNTKPIPNTRDKRPMLSSCRLLDKNPFTDWDSLVERITRDTDQHASLFMQQKLKSATQEQKQLIFKAIFRQVYALMTNRFGNFLVQRLFELGTPEQIKAVADKMRGHIFELTCEPFGCHVVQKALDCVEEASKAELVSELFTGIPETITHKYACHVWQKVFELRWIQVPAPPVMQRLHAVLQGQWTQVALDETGSLVIQNIFENLPEVDKRPVLNEVLDNILVIAKGQWGNWVVQHILEQAEKKSDREMAFDAVIEEAVQLSMDQFASKVVEKTLRIGGPQFIAKFIKRICETSYANRPRMALVDIASDQYGNYVIQWLINHASEEQKAFICRSIKRHMVSLRGSKYGQRVAFLVEKVLRNYEMTTYPMQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N7S7</accession>
    <name>A0A1C7N7S7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">histone deacetylase</fullName>
            <ecNumber evidence="3">3.5.1.98</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">clr3</name>
        <name evidence="13" type="ORF">A0J61_06780</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>N(6)-acetyl-L-lysyl-[histone] + H2O = L-lysyl-[histone] + acetate</text>
            <dbReference type="Rhea" id="RHEA:58196"/>
            <dbReference type="Rhea" id="RHEA-COMP:9845"/>
            <dbReference type="Rhea" id="RHEA-COMP:11338"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29969"/>
            <dbReference type="ChEBI" id="CHEBI:30089"/>
            <dbReference type="ChEBI" id="CHEBI:61930"/>
            <dbReference type="EC" id="3.5.1.98"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the histone deacetylase family. HD type 2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.5.1.98" evidence="3"/>
    <dbReference type="EMBL" id="LUGH01000425">
        <property type="protein sequence ID" value="OBZ85180.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N7S7"/>
    <dbReference type="FunCoup" id="A0A1C7N7S7">
        <property type="interactions" value="80"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N7S7"/>
    <dbReference type="InParanoid" id="A0A1C7N7S7"/>
    <dbReference type="OrthoDB" id="424012at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000118">
        <property type="term" value="C:histone deacetylase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0141221">
        <property type="term" value="F:histone deacetylase activity, hydrolytic mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0040029">
        <property type="term" value="P:epigenetic regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.800.20:FF:000005">
        <property type="entry name" value="histone deacetylase 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.800.20">
        <property type="entry name" value="Histone deacetylase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000286">
        <property type="entry name" value="HDACs"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023801">
        <property type="entry name" value="His_deacetylse_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037138">
        <property type="entry name" value="His_deacetylse_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023696">
        <property type="entry name" value="Ureohydrolase_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10625:SF5">
        <property type="entry name" value="HISTONE DEACETYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10625">
        <property type="entry name" value="HISTONE DEACETYLASE HDAC1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00850">
        <property type="entry name" value="Hist_deacetyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01270">
        <property type="entry name" value="HDASUPER"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52768">
        <property type="entry name" value="Arginase/deacetylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0678">Repressor</keyword>
    <keyword evidence="8" id="KW-0804">Transcription</keyword>
    <keyword evidence="7" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Histone deacetylase" evidence="12">
        <location>
            <begin position="239"/>
            <end position="536"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="62"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="133"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="79"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="152"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="13">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012111"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00048287"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF00850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="OBZ85180.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="575" mass="64160" checksum="1354271136C8263E" modified="2016-11-30" version="1" fragment="single">LGSLPVVETIVLSSDDEDEQKTVHLPLDIEQEIDAEIDALMPLTVGIKSNKDTEVVMATKKSLVPSDDEASEISRNELDELDSTGDEEETTSTKPLITTTIAAAAVETTAHPHFSFFAPRSVPTSEPKPVYTIKLNPPKPQSVVEEEEIGISSPTKRQPARQSRNRVSTYNDLENSVNLEQLLEHQEPQSMQFIRRAPKSKPTVVEQLVPLNRRRSLKTGFVYDTAMSYHATPDPMEIHPEDPRRIFKIFHIMDRHGLLKECKRIKSRRATKQEILLVHNIIHYRKIRATSALKSRQEYMAMEHNFDSIYLNSNSFESSLYAVGSLIELLEAVVLDKVKNAFAIIRPPGHHAEMDMPMGFCLFNNVAIATRDCIKRLGAKKVLIVDWDVHFGNGTQSIFSEDPDVLYVSLHRFEDASFYPSDHKGAAHYTGHGRGLGKTVNVPWPCAGMTDADYIYAFQHIIMPISMEFNPDVVIVSAGFDAAINDPIGKCKVTPAGYGQMTHMLKGLANGKLLIALEGGYDLNSIAVSALACMNVLLGDAPDIIDSNLVPKKECIETIEIVRNVQQKYWKSLSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N7S9</accession>
    <name>A0A1C7N7S9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Translin-associated protein X</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">Tsnax</name>
        <name evidence="6" type="ORF">A0J61_06797</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the translin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000427">
        <property type="protein sequence ID" value="OBZ85152.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N7S9"/>
    <dbReference type="FunCoup" id="A0A1C7N7S9">
        <property type="interactions" value="537"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N7S9"/>
    <dbReference type="InParanoid" id="A0A1C7N7S9"/>
    <dbReference type="OrthoDB" id="31005at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd14820">
        <property type="entry name" value="TRAX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.190">
        <property type="entry name" value="Translin, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.200">
        <property type="entry name" value="Translin, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016069">
        <property type="entry name" value="Translin_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002848">
        <property type="entry name" value="Translin_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016068">
        <property type="entry name" value="Translin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036081">
        <property type="entry name" value="Translin_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10741">
        <property type="entry name" value="TRANSLIN AND TRANSLIN ASSOCIATED PROTEIN X"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01997">
        <property type="entry name" value="Translin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74784">
        <property type="entry name" value="Translin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005902"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OBZ85152.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="239" mass="28090" checksum="4FCD56453CB4CE03" modified="2016-11-30" version="1">MSLQTQAFFKECRDVLDDHHDRRERIIKVSRDITAQSKKMIFALHRAAQSNQKYKEADQKQAELLDLFKKLAIDIQGLNYHRYAKSFSGGFEEFIEAVAFYHFLLHQDVISKEQIDNYFKDEQGNMITCLFTPTLQILGLADFTGELMRHAIHVVSTGRYEQALNICKLLRKIDLDFEIVSTFYMPQLNKKLGALKSSIKKVEQACYTFQIRGSEYPKEMYLSIIKNHQERYEQEQQEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N821</accession>
    <name>A0A1C7N821_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DNA helicase</fullName>
            <ecNumber evidence="3">3.6.4.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">mph1_1</name>
        <name evidence="12" type="ORF">A0J61_06744</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the DEAD box helicase family. DEAH subfamily. FANCM sub-subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.12" evidence="3"/>
    <dbReference type="EMBL" id="LUGH01000422">
        <property type="protein sequence ID" value="OBZ85207.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N821"/>
    <dbReference type="InParanoid" id="A0A1C7N821"/>
    <dbReference type="OrthoDB" id="164902at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043138">
        <property type="term" value="F:3'-5' DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000400">
        <property type="term" value="F:four-way junction DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009378">
        <property type="term" value="F:four-way junction helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045003">
        <property type="term" value="P:double-strand break repair via synthesis-dependent strand annealing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036297">
        <property type="term" value="P:interstrand cross-link repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd18033">
        <property type="entry name" value="DEXDc_FANCM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd12091">
        <property type="entry name" value="FANCM_ID"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="CDD" id="cd18801">
        <property type="entry name" value="SF2_C_FANCM_Hef"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000861">
        <property type="entry name" value="Fanconi anemia, complementation group M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039686">
        <property type="entry name" value="FANCM/Mph1-like_ID"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044749">
        <property type="entry name" value="FANCM_DEXDc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006935">
        <property type="entry name" value="Helicase/UvrB_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14025">
        <property type="entry name" value="FANCONI ANEMIA GROUP M FANCM FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14025:SF20">
        <property type="entry name" value="FANCONI ANEMIA GROUP M PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04851">
        <property type="entry name" value="ResIII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 12" id="KW-0347">Helicase</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="10">
        <location>
            <begin position="110"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="11">
        <location>
            <begin position="462"/>
            <end position="625"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="10">
        <location>
            <begin position="753"/>
            <end position="894"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="11">
        <location>
            <begin position="1078"/>
            <end position="1241"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="15"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1448"/>
            <end position="1489"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1653"/>
            <end position="1694"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1780"/>
            <end position="1817"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1865"/>
            <end position="1887"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1973"/>
            <end position="1995"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="31"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="1455"/>
            <end position="1464"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="1668"/>
            <end position="1684"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="1685"/>
            <end position="1694"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="1794"/>
            <end position="1816"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="1975"/>
            <end position="1987"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009889"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="OBZ85207.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="2100" mass="239281" checksum="92B567D137ADB0D8" modified="2016-11-30" version="1">MSEDEFDMLDLTANSIEADHQPPTNDNMTIPEDDFSDDDDDLDLDQLVEVTETVEQQRGQITFVSFGEHDPDPPPPLPESTPSFHPFDAENLRTWIYPTNYTIRGYQFNIVQKAIFNNTLVALPTGLGKTFIAAVVMFNYYRWFPNSKIIFMAPTRPLVEQQIEACYTVCGLPQEDTVDMMGNTSPAKRKELWKSKRVFFATPQTVQKDLENAICPGDKIACIVVDEAHKATGNFAYTVVVKRVSKVNKHFRVLALTATPGSNLDAVQDVVNNLHITQIQIRTEDSMDIREFSHGKNIQHIVVKLSYTEGSTGILPRVIDDYKNKVFGPLLLELSKKPTTVSSDVDRNSSFGLRSARLHFYQNARNLNNALKFQVTALFLVAEHAARAYELLCQHGVVPFVESIDSVLEEFKNTRETGKKLNKSQKAFLDNNVLQAILRNAKNEMSKPDFIGHPKMDKLVSILINHFANLPEGESSKVMIFSSYRTSVQDICQVLNRHAPMLRPSFFVGQASDKNGIKGLKQSEQQEVIQKFKLDVFNILVSTSIGEEGLDIGEVDLIICFDSQSSPIRMLQRMGRTGRKRKGKCILLMTESEERKFQQAKDAYARIQSLIARGGLIKYYPNNPVILPNNYKPALCRKKLEVGQFKRKVGPKRQKRAMDQEDLYHTPEGFLRPEVKKSFIRSFNNRNHTFSSTEDLFNRFWPVQRMIKSINRFMPIQTAQKPTRRVGHSRRTIQFVHLVQKMEHRILNPNDKIELLKTTTTTRKKQTQLHLPSKGKAKQQTTLFQHLIGGEDTVDMMGNTSPAKRKELWKSKRVFFATPQTVQKDLENAICPGDKIACIVVDEAHKATGNFAYTVVVKRVSKVNKHFRVLALTATPGSNLDAVQDVVNNLHITQIQIRTEDSMDIREFSHGKNIQHIVVKLSYTEGSTGILPRVIDDYKNKVFGPLLLELSKKPTTVSSDVDRNSSFGLRSARLHFYQNARNLNNALKFQVTALFLVAEHAARAYELLCQHGVVPFVESIDSVLEEFKNTRETGKKLNKSQKAFLDNNVLQAILRNAKNEMSKPDFIGHPKMDKLVSILINHFANLPEGESSKVMIFSSYRTSVQDICQVLNRHAPMLRPSFFVGQASDKNGIKGLKQSEQQEVIQKFKLDVFNILVSTSIGEEGLDIGEVDLIICFDSQSSPIRMLQRMGRTGRKRKGKCILLMTESEERKFQQAKDAYARIQSLIARGGLIKYYPNNPVILPNNYKPALCRKKLEVGQFKRKVGPKRQKRAMDQEDLYHTPEGFLRPEVKKSFIRSFNNRNHTFSSTEDLFNRFWPVQRMIKSINRFMPIQTAQKPTRRVGHSRRTIQFVHLVQKMEHRILNPNDKIELLKTTTTTRKKQTQLHLPSKGKAKQQTTLFQHLIGGGGNSRLNSSRSKRVNDDDFADFMETHDVAQFIDTDAIFSSEQDSAFSSKSKDKGKSKEVSIANNQRKDKEQQDSLSWDPMLPDSLYDEVEPLQDRHKEMQVSLSDSPKIVSDPTSFPITATSLNAAPLDLSSPKDESDDFFDDLDDALLADALMITHEKNIGFDDPLSPKYPFEMDSAVSIKPVQFTWSEKIPILSSKAKELLEKRQATMKALVGRFISMRLTSHSLPDITHNLTEPMEIDTSIIVLDDSQPIKSPSPVKPLELEQPKEKKDQEHPEEIEQEQPENDEDEFDQFDFMSDGMLANFFENKLSEDDPHEGFSQFMFEEESNQKTSQSQSTQFMAQKSSLYANPPRALSLVEDKHEKEDEVFIFDFNQPMSDSSDNEDKQSTNIISSPDSQDQSTTHIPTLTIKSPLPSRIKSVMTTPIVLTSDEEPDTAIPSPKVKSSPNLLNELAKGAYAPSPLRHDMPSSENEESPLVVQRKRRWRQPTVEEEMEDTIEVVKSRRKRLRQRSXGNALSPLDEDLIITPPPRKQLLKRLQQSGYNAHEHHRRHHHHRLTYDANNPFFDMEAEKSSDGGHTTDEDNEEEGESLLDSFINDNSDLLGSNSSVHSHISTDKHLYAQSLLQDEPHPNRKHWMNRFDANKWLTVNQEDDNVVQSDDEQEGDAESIQDFSSDLVFTHQNRTDFVSGDDDFM</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N863</accession>
    <name>A0A1C7N863_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Oxidoreductase AflY</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">aflY</name>
        <name evidence="2" type="ORF">A0J61_06701</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000418">
        <property type="protein sequence ID" value="OBZ85247.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N863"/>
    <dbReference type="STRING" id="101091.A0A1C7N863"/>
    <dbReference type="InParanoid" id="A0A1C7N863"/>
    <dbReference type="OrthoDB" id="10004862at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025337">
        <property type="entry name" value="Questin_oxidase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35870">
        <property type="entry name" value="PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_5G03330)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35870:SF1">
        <property type="entry name" value="PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_5G03330)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14027">
        <property type="entry name" value="Questin_oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ85247.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="480" mass="54013" checksum="C4FEBF4326FD1786" modified="2016-11-30" version="1">MSSFKPTIPSKPEAFTFVAPGISPEAAKLSEQLLIKSDGFHIFFNDKKFHNHLNHHLLAAYSFGASTERLQKIFDINASYQRPMPPSIGEITRENYKQYLGNADAYTSFLSFFKSEIDHFGITETVRRFVWSNDFLARTVGGLYHPLIHIGYGLEFNLPGMAAEGLAMAAMTEDHFLPLIPLQPELNKASIIPSQAQTLAENATSSARGYAAKALDQLTNQLATRLGIADRTATQHYEDSADRSIPATIDTPDYLKHHSLFAIFNHIREDPALQGLFKSTDEVRFKLVLKNEKAVERIRHYVAQWGLTENTIVIQKKMKELYSFVAILAGSTALHPNHPGKLRPSFFLVHALTSVEFLHQFVTRIAPSEAVSLIQAHLAITIVYFLTEGSPKFNLEGLLNYKSPIQSEKFENRWFPVMDASLDQEESHVIKAVRACVVGQIIYGPHDDSRLDDIWFKTAELVVDANGKWDFDGVGFEDTW</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N8D6</accession>
    <name>A0A1C7N8D6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">A0J61_06749</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000422">
        <property type="protein sequence ID" value="OBZ85208.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N8D6"/>
    <dbReference type="STRING" id="101091.A0A1C7N8D6"/>
    <dbReference type="InParanoid" id="A0A1C7N8D6"/>
    <dbReference type="OrthoDB" id="8117402at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="3">
        <location>
            <begin position="49"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="3">
        <location>
            <begin position="203"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="100"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="144"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="116"/>
            <end position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OBZ85208.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="263" mass="29842" checksum="2375EB4271CF1E2D" modified="2016-11-30" version="1">MIENKYASLVSLIDTIYPPLLCTLCDTVFTTKNASSLHFIEKHNKKSRYICIHPHCDRRFVSKGALRFHISRSHLVMQAKKPLPDPPLYYQPAIQKKIKKTKKTSNHASPILSDISLKHEEEEEVDHHHEDDIDDLIIPSSPLSSCSSLSSAPDSPLLQSTTSVSPTPLSPFSLYHHHKKTSSKKPTLSAKAEQFLNSIYPPLQCPSCNQLFGRKTNVIKHLTEAHIGQEPYRCIYPSCNHPRLYATREGLVYHIVHAHDKIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N8F4</accession>
    <name>A0A1C7N8F4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_07041</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000456">
        <property type="protein sequence ID" value="OBZ84909.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N8F4"/>
    <dbReference type="InParanoid" id="A0A1C7N8F4"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="57"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="75"/>
            <end position="86"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ84909.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="124" mass="14287" checksum="298F1C279CB519AD" modified="2016-11-30" version="1">MEENKWETYSEEMEDDDLAMEVEEMEDEDMTRNSTTGSQLGSRQSYLEEFSSKASGAFKGGSVAPMQKQPIDYRSSVSSPMHSFSDMSDEKNETDDLLTQMLSKMAHIKFFRDFEDDFDEDDLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N8N4</accession>
    <name>A0A1C7N8N4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">ubiquitinyl hydrolase 1</fullName>
            <ecNumber evidence="3">3.4.19.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">USP36</name>
        <name evidence="10" type="ORF">A0J61_06637</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 12 13">
            <text>Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).</text>
            <dbReference type="EC" id="3.4.19.12"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peptidase C19 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.19.12" evidence="3"/>
    <dbReference type="EMBL" id="LUGH01000411">
        <property type="protein sequence ID" value="OBZ85308.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N8N4"/>
    <dbReference type="STRING" id="101091.A0A1C7N8N4"/>
    <dbReference type="InParanoid" id="A0A1C7N8N4"/>
    <dbReference type="OrthoDB" id="420187at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004843">
        <property type="term" value="F:cysteine-type deubiquitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016579">
        <property type="term" value="P:protein deubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.70.10">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050164">
        <property type="entry name" value="Peptidase_C19"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001394">
        <property type="entry name" value="Peptidase_C19_UCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028889">
        <property type="entry name" value="USP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018200">
        <property type="entry name" value="USP_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24006">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24006:SF758">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 36"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00443">
        <property type="entry name" value="UCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00973">
        <property type="entry name" value="USP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50235">
        <property type="entry name" value="USP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0645">Protease</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0788">Thiol protease</keyword>
    <keyword evidence="5" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="USP" evidence="9">
        <location>
            <begin position="113"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="423"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="446"/>
            <end position="457"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OBZ85308.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="596" mass="68745" checksum="0D7B8A19D56C8B31" modified="2016-11-30" version="1">MATQSQQRAANVVKGGKLEPLSQKNTINGLLSRSIKFRKSRYVDHKLEQFKQKFAPVNGVTGVVHAKTAHAYDTQTDMLVEKVDQYGFEQPMKVLFSKDKLSVGWQEIYPVGSGLKDMGHLSSLNAVLQVLTYTPALANFLMNRTHGANCTIQDYCFLCAVEEHVRTALKGSPYALQPRLLVGKLKKMSKKSSSKDAFDVWAYFMEQMQSFLLSERTSKDTRIQETTAFYQMFGGYIQKKFTCPSCNALDHFYDSFLYLSLDLTQCSTVERCVSRHFKNKVSLTRECSSCQHEGQVECTQSIYRPPMNLVIQLDRFDQQSKNNKMVKFEERMDIRYAVTETERGQVDSTYQLYGIIVHTGESLHDGHYVAYVKSSNGIWYCMDNETVQVVSLKRLLEQNVYMLFYHNIPPKIVSAKKKPIHEPATSLEKTPQSLLEKEEEVEVEEKEEKVDDSIEDKEKEDALRKAIEEASHKEKRENEAAIVVRHDETMQSKRDKLDALIQREEVESKSAEVKQMLLTKVANNQFQDEIDTWEDTGVAQKRNQVLKQMKTKRKKVDSYDLDYDRGKLKKVKSKKKDDKFNKPNMFQLAADMKKKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N8P8</accession>
    <name>A0A1C7N8P8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="10">V-type proton ATPase subunit e</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">VMA9</name>
        <name evidence="10" type="ORF">A0J61_06488</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the V-ATPase e1/e2 subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000394">
        <property type="protein sequence ID" value="OBZ85461.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N8P8"/>
    <dbReference type="FunCoup" id="A0A1C7N8P8">
        <property type="interactions" value="101"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N8P8"/>
    <dbReference type="InParanoid" id="A0A1C7N8P8"/>
    <dbReference type="OrthoDB" id="1508846at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000220">
        <property type="term" value="C:vacuolar proton-transporting V-type ATPase, V0 domain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046961">
        <property type="term" value="F:proton-transporting ATPase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007035">
        <property type="term" value="P:vacuolar acidification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008389">
        <property type="entry name" value="ATPase_V0-cplx_e1/e2_su"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12263:SF0">
        <property type="entry name" value="V-TYPE PROTON ATPASE SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12263">
        <property type="entry name" value="VACUOLAR ATP SYNTHASE SUBUNIT H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05493">
        <property type="entry name" value="ATP_synt_H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="7" id="KW-0406">Ion transport</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="36"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OBZ85461.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="73" mass="8149" checksum="E7EE7ACD5AD32236" modified="2016-11-30" version="1">MSGYNIVLGFLVVAALSALGYFLTPKGKDQTVIRTVIIMSLACCYLMWAVTYLAQLHPLIYPRKSGLRPPHHE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N8W7</accession>
    <name>A0A1C7N8W7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_06410</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000385">
        <property type="protein sequence ID" value="OBZ85540.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N8W7"/>
    <dbReference type="InParanoid" id="A0A1C7N8W7"/>
    <dbReference type="OrthoDB" id="2285968at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008889544" evidence="2">
        <location>
            <begin position="20"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="181"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="183"/>
            <end position="205"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ85540.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="223" mass="22332" checksum="B1A7F08D79B24032" modified="2016-11-30" version="1">MKLSLLLSSLSAFVCTASASTLIITDNFVGGHGLAKRDKRIPYSNLPSTTCNVPSTCSSIGGNVSCRCSDIMTTCINTQGQYCWGSSTLTSTSCPTIPDSCKSTLASTASCLCNSNNVLCVDNSNTYCYGTISGSNVSLTAIPYAQSSGQGYVFASSTAAAASSAAPAATSSASLANTMSVEGAPSGSPTAEASASPTSGSNKLTGSSSLALGLAMVAYMALY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N9E1</accession>
    <name>A0A1C7N9E1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Inorganic pyrophosphatase</fullName>
            <ecNumber evidence="4">3.6.1.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Pyrophosphate phospho-hydrolase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="primary">ipp-1</name>
        <name evidence="12" type="ORF">A0J61_06244</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>diphosphate + H2O = 2 phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:24576"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="EC" id="3.6.1.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the PPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.1.1" evidence="4"/>
    <dbReference type="EMBL" id="LUGH01000368">
        <property type="protein sequence ID" value="OBZ85710.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N9E1"/>
    <dbReference type="STRING" id="101091.A0A1C7N9E1"/>
    <dbReference type="InParanoid" id="A0A1C7N9E1"/>
    <dbReference type="OrthoDB" id="1608002at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004427">
        <property type="term" value="F:inorganic diphosphate phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006796">
        <property type="term" value="P:phosphate-containing compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00412">
        <property type="entry name" value="pyrophosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.80.10:FF:000004">
        <property type="entry name" value="Inorganic pyrophosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.80.10">
        <property type="entry name" value="Inorganic pyrophosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008162">
        <property type="entry name" value="Pyrophosphatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036649">
        <property type="entry name" value="Pyrophosphatase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10286">
        <property type="entry name" value="INORGANIC PYROPHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00719">
        <property type="entry name" value="Pyrophosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50324">
        <property type="entry name" value="Inorganic pyrophosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00387">
        <property type="entry name" value="PPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006220"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00032535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00040300"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00047820"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="OBZ85710.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="300" mass="34814" checksum="E46F0FAF398D093C" modified="2016-11-30" version="1">MLRKIPFVRYSSTYRTVSVGKPFTAAHRVYVEKDGQIISPFHDIPLYANKEDKQVVNMVVEIPRWTNAKVEISTDEQFNPLKQDVKKGKPRFVRNCFPHKGYIWNYGALPQTWEDPTYIHEDTNAKGDNDPIDVIEIGQEIGKQGQIKQVKVLGVMAMLDEGETDWKVVAIDTKDPLASKIHDVEDIDHHFPGLLDATRHFFRVYKVPDGKPENEFAYNGECKNQTFANTIVAETHEAWQRLIEGKVPKTTDTYHLEVHNLTVEKSPYRTDKQMTVKEETFENIKEQEVKEYDPKWYFVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N9H0</accession>
    <name>A0A1C7N9H0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">2-isopropylmalate synthase</fullName>
            <ecNumber evidence="3">2.3.3.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">leuA</name>
        <name evidence="10" type="ORF">A0J61_06360</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Amino-acid biosynthesis; L-leucine biosynthesis; L-leucine from 3-methyl-2-oxobutanoate: step 1/4.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.3.13" evidence="3"/>
    <dbReference type="EMBL" id="LUGH01000381">
        <property type="protein sequence ID" value="OBZ85588.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N9H0"/>
    <dbReference type="STRING" id="101091.A0A1C7N9H0"/>
    <dbReference type="InParanoid" id="A0A1C7N9H0"/>
    <dbReference type="OrthoDB" id="2015253at2759"/>
    <dbReference type="UniPathway" id="UPA00048">
        <property type="reaction ID" value="UER00070"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003852">
        <property type="term" value="F:2-isopropylmalate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010177">
        <property type="term" value="F:methylthioalkylmalate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009098">
        <property type="term" value="P:L-leucine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd07940">
        <property type="entry name" value="DRE_TIM_IPMS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.238.260:FF:000001">
        <property type="entry name" value="2-isopropylmalate synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.70:FF:000010">
        <property type="entry name" value="2-isopropylmalate synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.260">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01025">
        <property type="entry name" value="LeuA_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050073">
        <property type="entry name" value="2-IPM_HCS-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013709">
        <property type="entry name" value="2-isopropylmalate_synth_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002034">
        <property type="entry name" value="AIPM/Hcit_synth_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054691">
        <property type="entry name" value="LeuA/HCS_post-cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036230">
        <property type="entry name" value="LeuA_allosteric_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005671">
        <property type="entry name" value="LeuA_bact_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000891">
        <property type="entry name" value="PYR_CT"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00973">
        <property type="entry name" value="leuA_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF002086">
        <property type="entry name" value="PRK00915.1-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10277:SF9">
        <property type="entry name" value="2-ISOPROPYLMALATE SYNTHASE 1, CHLOROPLASTIC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10277">
        <property type="entry name" value="HOMOCITRATE SYNTHASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22617">
        <property type="entry name" value="HCS_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00682">
        <property type="entry name" value="HMGL-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08502">
        <property type="entry name" value="LeuA_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00917">
        <property type="entry name" value="LeuA_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110921">
        <property type="entry name" value="2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51569">
        <property type="entry name" value="Aldolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00815">
        <property type="entry name" value="AIPM_HOMOCIT_SYNTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00816">
        <property type="entry name" value="AIPM_HOMOCIT_SYNTH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50991">
        <property type="entry name" value="PYR_CT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="8" id="KW-0100">Branched-chain amino acid biosynthesis</keyword>
    <keyword evidence="4" id="KW-0432">Leucine biosynthesis</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Pyruvate carboxyltransferase" evidence="9">
        <location>
            <begin position="7"/>
            <end position="280"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004689"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009396"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012973"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022430"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OBZ85588.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="550" mass="59555" checksum="18FEB8332A5EB92C" modified="2016-11-30" version="1">MAATDKLVIFDTTLRDGEQSPGVTLNTEEKIEIAKQLSRLGVDVLEAGFPIASIGDFEAVQRIAREVGPLMVGRENIGQPMTICGLARSTPNDIKRCAEAIAPAPRKRIHVFLATSDLHLKYKLKIDREECIKRAVAAVTLARSLVDEVEFSPEDAGRSDRDFLCQVLGKVIEAGATTLNIPDTVGYNTPEEYGELIKYLVQNTPNADKAIFSTHCHNDLGLATANTLAGICNGARQVEVTINGIGERAGNTAMEEVVMAIHTHPNYYPVHHTINTTMIYRTSQLVSTLSGMMVQSNKAIVGRNAFLHESGIHQDGVLKNRQTYEIITPETVGVTDINLVLGKHSGRNAFRERCKELGFPDIVEEDFQKAFDSFKNLCDKKKNVNDADILAILSNQISTAGTTAFFTLVSAQVVSGSDTSSTASVKLFDIKADKQVTDAAVGTNGPIEAIFDAIQRCVGRQFRLTKFDISAVGEGSDALGKAEIQVKADSSSVQDERLTKIAFAASVADIDITIAAAKAYINAINKLLVWESELAAGTARSIGEERQVDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NB36</accession>
    <name>A0A1C7NB36_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 11">ATP synthase subunit d, mitochondrial</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">atp7</name>
        <name evidence="13" type="ORF">A0J61_05618</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 11">Mitochondrion inner membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the ATPase d subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000308">
        <property type="protein sequence ID" value="OBZ86335.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NB36"/>
    <dbReference type="FunCoup" id="A0A1C7NB36">
        <property type="interactions" value="217"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NB36"/>
    <dbReference type="InParanoid" id="A0A1C7NB36"/>
    <dbReference type="OrthoDB" id="35799at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045259">
        <property type="term" value="C:proton-transporting ATP synthase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046933">
        <property type="term" value="F:proton-transporting ATP synthase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.280.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008689">
        <property type="entry name" value="ATP_synth_F0_dsu_mt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036228">
        <property type="entry name" value="ATP_synth_F0_dsu_sf_mt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12700">
        <property type="entry name" value="ATP SYNTHASE SUBUNIT D, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05873">
        <property type="entry name" value="Mt_ATP-synt_D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005514">
        <property type="entry name" value="ATPase_F0_D_mt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161065">
        <property type="entry name" value="ATP synthase D chain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0138">CF(0)</keyword>
    <keyword evidence="12" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6 11" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="8 11" id="KW-0406">Ion transport</keyword>
    <keyword evidence="10 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="9 11" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="7 11" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 11" id="KW-0813">Transport</keyword>
    <feature type="coiled-coil region" evidence="12">
        <location>
            <begin position="91"/>
            <end position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00021688"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022547"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRNR" id="PIRNR005514"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="OBZ86335.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="171" mass="19148" checksum="CA10EDE79F598231" modified="2016-11-30" version="1">MASSVRAAAINWAKLSVSLPQETVASLQAFRKRNDEVKRVLAELKEQSTTVDFAQYRKVLKNQAIVDQAEKAVSGFKPVAYNLDAQLNAINQFETKAVAKAEKTVQQIEHELKDLHATLNNIEGSRPIEQLTVDDIIVAKPELTKNIEENLKKGQFSVPGYKEKFGDISYF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NBA9</accession>
    <name>A0A1C7NBA9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_05675</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000313">
        <property type="protein sequence ID" value="OBZ86280.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NBA9"/>
    <dbReference type="InParanoid" id="A0A1C7NBA9"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ86280.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="378" mass="43508" checksum="CCAE8F15F1CC1698" modified="2016-11-30" version="1">MRKIKRRKLSPLEDTNQILSTPIECNSHHPILSLTPQDRQGIHLFVPLEAFWSPEALYEEHLRALDQSLYDFGVADMEIDDVPTEAAYDDDMSFIFDHNQPCVHKMEAKRQAIQQDDISFDQPPTKRSCRRKFIPDILVLNISVPNIPAPEIVVSKPITPKVATPEPPAPKTLTPKPPTECSICHVNLSPEHYRSERKRLDSKCIYRGSLCCVGCARFMAYAKIDQEQREIINYLITGQLPDHQRPPVLSGSQVYVRLEKRYDQIVSRHRTKVTNRGRCPLVLDDLVRIYMNQNQTCQVTGVLCHLHNPKYAKVPYWALTFDHITPVSHRLNDPSVWAAGNLQIMSCVLNNVKNDTKNIEIIDWYKRFLKAIKTKAIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NBH9</accession>
    <name>A0A1C7NBH9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_05547</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000302">
        <property type="protein sequence ID" value="OBZ86401.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NBH9"/>
    <dbReference type="STRING" id="101091.A0A1C7NBH9"/>
    <dbReference type="InParanoid" id="A0A1C7NBH9"/>
    <dbReference type="OrthoDB" id="1099063at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018790">
        <property type="entry name" value="DUF2358"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31094">
        <property type="entry name" value="RIKEN CDNA 2310061I04 GENE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31094:SF2">
        <property type="entry name" value="RIKEN CDNA 2310061I04 GENE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10184">
        <property type="entry name" value="DUF2358"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ86401.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="228" mass="26792" checksum="1271D105B4B05005" modified="2016-11-30" version="1">MILSYSLKRTLSRRLFNSIHYRPLTQSNRPKEYELRVGFAIATLQDDIPLFFSRGLTEHTIYSPHIKLSDPHYTKLSIHGRTAYLGIAQMLRWSSSMYFDDIQLEILKMRVLSEDDPLSMDEDMYGDTMFSSIHQAEDDLKSRGPVKRLEVRWKLEGTNHGHWLRSQPSTRHIEGVFVYHFDEDGYIDEHRIQRIVPPPSKRVVLLHSLGVRLRSLFWERPPVLNPGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NC15</accession>
    <name>A0A1C7NC15_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Beta-lactamase domain-containing protein 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">lact-2</name>
        <name evidence="2" type="ORF">A0J61_05823</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000326">
        <property type="protein sequence ID" value="OBZ86126.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NC15"/>
    <dbReference type="STRING" id="101091.A0A1C7NC15"/>
    <dbReference type="InParanoid" id="A0A1C7NC15"/>
    <dbReference type="OrthoDB" id="5946976at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.710.10">
        <property type="entry name" value="DD-peptidase/beta-lactamase superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001466">
        <property type="entry name" value="Beta-lactam-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012338">
        <property type="entry name" value="Beta-lactam/transpept-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052907">
        <property type="entry name" value="Beta-lactamase/esterase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43319">
        <property type="entry name" value="BETA-LACTAMASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43319:SF3">
        <property type="entry name" value="BETA-LACTAMASE-RELATED DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00144">
        <property type="entry name" value="Beta-lactamase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56601">
        <property type="entry name" value="beta-lactamase/transpeptidase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Beta-lactamase-related" evidence="1">
        <location>
            <begin position="64"/>
            <end position="228"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ86126.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="454" mass="50770" checksum="B509C2A19F9A3231" modified="2016-11-30" version="1">MSYCLKTVFIIPVVAYMVYRQLNSGPFLSMTCSLTGFQCPKSIPVNGFADEQFKDTYDVFLDNIKKGYDIGAGLSVYVDGREVIHLQAGWQDPTKRIEYTDNTLQIVFSSSKAFSSIVVAQLVEKGLLSYDEKIATYWPEFAQGNKENVTLSDLMRHMAGVGALDRPLSLADVKDPAVFSNILASQPHNFGGVPTHAYHAITQGWYLNEIIRRVTDGKTIDDFAREYQTKYGCEWYFKPDATEGVDVNRISTFYERPMIYQLVDLIKIVFSPHRDMTLLRNIFDKQSIFHKSMTNPNIDQVKGIMNNNDPLRRAIEGPSYSGHTNAHSIAKLAAMMANKGKAIVPGEPDLMSEKTFDEATTFISNESDLVFSGFPMCNLKGGLLAIDNSLFLGDMEEESHFEGGFGAGGSLFLYNTKHKIAIGYVTNSYLEHLPPDIRTTRIVRSVLKAVKGTQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NCF6</accession>
    <name>A0A1C7NCF6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Protein VAC14</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">A0J61_05198</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the VAC14 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000274">
        <property type="protein sequence ID" value="OBZ86751.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NCF6"/>
    <dbReference type="FunCoup" id="A0A1C7NCF6">
        <property type="interactions" value="715"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NCF6"/>
    <dbReference type="InParanoid" id="A0A1C7NCF6"/>
    <dbReference type="OrthoDB" id="5574975at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010008">
        <property type="term" value="C:endosome membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000329">
        <property type="term" value="C:fungal-type vacuole membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070772">
        <property type="term" value="C:PAS complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006661">
        <property type="term" value="P:phosphatidylinositol biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021133">
        <property type="entry name" value="HEAT_type_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026825">
        <property type="entry name" value="Vac14"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021841">
        <property type="entry name" value="VAC14_Fig4p-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16023:SF0">
        <property type="entry name" value="PROTEIN VAC14 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16023">
        <property type="entry name" value="TAX1 BINDING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12755">
        <property type="entry name" value="Vac14_Fab1_bd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11916">
        <property type="entry name" value="Vac14_Fig4_bd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50077">
        <property type="entry name" value="HEAT_REPEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="HEAT" evidence="5">
        <location>
            <begin position="88"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="domain" description="Vacuolar protein 14 C-terminal Fig4-binding" evidence="8">
        <location>
            <begin position="566"/>
            <end position="743"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="280"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="432"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="797"/>
            <end position="839"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="878"/>
            <end position="944"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="22"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="318"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="435"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="803"/>
            <end position="818"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="881"/>
            <end position="914"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="922"/>
            <end position="938"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004308"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF11916"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OBZ86751.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="944" mass="104471" checksum="6D4FAA4064C278DE" modified="2016-11-30" version="1">METSIFSPSLVKGLTDKIYDRRKAAALEIERLVRENEDSKERITQIVDALVQEFVYSNNPYARYGGLIGLAATSIALGPGVSQYLDIIVPPILSCFSNQDQKVRYYACESMYNIAKVAKGEVLRYFNSVFDALCKLSADSEISVKNGAELLDRLIKDIVSELSTTYVSPYSEPYNSVEEGGDELPTPSSLPRNTAFSLPRFIPLLSQRIYVRNSAARQFLVSWMCVLDSIPDLELISFLPEFLDGLIRCLNDASEDVRVATNGLLQDFLSEIKEAAAARSLQIQREEDQRKRLSQTGTKEENKESLSEAAAADQEPGTVEEDPVDQPETPDTENDGHGKGTYVPGQGVIVQYSRIVEILVPHLSSAEEDIQKTALLWINAFIEIAKDVIIKFTPEIIKAVLPSLAHPVAGIRIIALEMNHNLQKLVLETPVHQPEPTTSKSDPSGGVQLQQKKNKSALMNQVDGNADPFDYQATVANLRLQFLNQHEETRVASLDWLLMLHKKAPNKILASDDGTFPALLKTLSDSSEEVVRRDLQLLAQISSHSDHEYFRSFIVSLLSLFSTDRRLLETRGSLIIRQLCMSLDPERIYCAIADILEQDEDLEFASIMIQNLNIILVTSSELSDLRKRLRNLELKDNQRLFNTLYRSWCHNAVSALSLCLLSQVYEHAANMLQIFAELEITVNMLIQIDKLVQLLESPVFTYLRLQLLEPGKYPYLFKCLYGILMLLPQSSAFSTLRNRLNSVSSLGFLHVLPKSPVASSTTTSSDRKQLGKTKAEEISTIKYQDLLTHFKSVQARHEKQRKQVLQSTSRTSAVNNASRSRRPRTLYGGNGVEGSPNQIFSQENKGLGISSTINNNLIVGGGGIRNGMASLGLSPTSGHYSNASNNSNDSLSSSSGTVNNNSSLSNPNYSSGSTNLGGGGSSLNAGHSNASARLSASARRNRRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NCK5</accession>
    <name>A0A1C7NCK5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Heat shock protein HSS1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">HSS1_0</name>
        <name evidence="8" type="ORF">A0J61_05218</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the heat shock protein 70 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000276">
        <property type="protein sequence ID" value="OBZ86728.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NCK5"/>
    <dbReference type="FunCoup" id="A0A1C7NCK5">
        <property type="interactions" value="523"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NCK5"/>
    <dbReference type="InParanoid" id="A0A1C7NCK5"/>
    <dbReference type="OrthoDB" id="2401965at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd10233">
        <property type="entry name" value="ASKHA_NBD_HSP70_HSPA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.34.10:FF:000002">
        <property type="entry name" value="Heat shock 70 kDa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.640.10:FF:000002">
        <property type="entry name" value="Heat shock 70 kDa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.40:FF:000172">
        <property type="entry name" value="Heat shock 70 kDa protein"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.30.30:FF:000001">
        <property type="entry name" value="heat shock 70 kDa protein-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1270.10:FF:000016">
        <property type="entry name" value="Heat shock protein 70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.40:FF:000026">
        <property type="entry name" value="Heat shock protein 70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.640.10">
        <property type="entry name" value="Actin, Chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.34.10">
        <property type="entry name" value="Substrate Binding Domain Of DNAk, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018181">
        <property type="entry name" value="Heat_shock_70_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029048">
        <property type="entry name" value="HSP70_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029047">
        <property type="entry name" value="HSP70_peptide-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013126">
        <property type="entry name" value="Hsp_70_fam"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF001413">
        <property type="entry name" value="PRK00290.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19375">
        <property type="entry name" value="HEAT SHOCK PROTEIN 70KDA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00012">
        <property type="entry name" value="HSP70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00301">
        <property type="entry name" value="HEATSHOCK70"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100934">
        <property type="entry name" value="Heat shock protein 70kD (HSP70), C-terminal subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100920">
        <property type="entry name" value="Heat shock protein 70kD (HSP70), peptide-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00297">
        <property type="entry name" value="HSP70_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00329">
        <property type="entry name" value="HSP70_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01036">
        <property type="entry name" value="HSP70_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0346">Stress response</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="612"/>
            <end position="652"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="512"/>
            <end position="539"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="7">
        <location>
            <begin position="614"/>
            <end position="636"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007381"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003322"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OBZ86728.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="652" mass="71094" checksum="DEA2FA8A560B1DD5" modified="2016-11-30" version="1">MSEGKSVGIDLGTTYSCVGVWQNDRVEIIANDQGNRTTPSYVGFTDSERLIGDAAKNQVAMNPYNTVFDAKRLIGRRFNDVEVQSDMKHWPFKVIDKDSKPIIQVEFKGETKTFTPEEISAMILVKMKETAEAYLGSVVKNAVITVPAYFNDSQRQATKDAGLIAGLNVQRIINEPTAAAIAYGLDKKVEGERNVLIFDLGGGTFDVSLLTIEDGIFEVKATAGDTHLGGEDFDNRLVSHFMQEFKRKFKKDISGNARAMRRLRTACERAKRTLSSSAQTTIEIDSLFEGVDFYTSLTRARFEELNQDLFRNTMDPVEKVLRDAKIDKGSVHDIVLVGGSTRIPKVQKLVSDFFNGKEPNKSINPDEAVAYGAAVQAAILSGDTSEKTQDLLLLDVAPLSLGIETAGGVMTALIKRNTTVPTKKSEVFSTYADNQPGVLIQVFEGERARTKDNNILGKFELTGIPPAPRGVPQIEVTFDVDANGILNVSALDKTTGKSNKITITNDKGRLSKEDIERMVNEAEKYKAEDEEAAARIQAKNGLESYAYNLRNTLQDEKVAGALPEEDKTKLKAAVDAAIEWLDASQEASKEEYESKQKEIEEVANPIMMKMYGQQQGGAPGAAPGGFPGGAAPGGFPGANTAETDGPSIEEVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NCW0</accession>
    <name>A0A1C7NCW0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="1">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">FRK1_2</name>
        <name evidence="13" type="ORF">A0J61_05101</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="1"/>
    <dbReference type="EMBL" id="LUGH01000266">
        <property type="protein sequence ID" value="OBZ86848.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NCW0"/>
    <dbReference type="FunCoup" id="A0A1C7NCW0">
        <property type="interactions" value="257"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NCW0"/>
    <dbReference type="InParanoid" id="A0A1C7NCW0"/>
    <dbReference type="OrthoDB" id="193931at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106310">
        <property type="term" value="F:protein serine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035556">
        <property type="term" value="P:intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000571">
        <property type="entry name" value="Maternal embryonic leucine zipper kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000003">
        <property type="entry name" value="Non-specific serine/threonine protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.310.80">
        <property type="entry name" value="Kinase associated domain 1, KA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028375">
        <property type="entry name" value="KA1/Ssp2_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001772">
        <property type="entry name" value="KA1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24346">
        <property type="entry name" value="MAP/MICROTUBULE AFFINITY-REGULATING KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24346:SF110">
        <property type="entry name" value="NON-SPECIFIC SERINE_THREONINE PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02149">
        <property type="entry name" value="KA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103243">
        <property type="entry name" value="KA1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50032">
        <property type="entry name" value="KA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 13" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="11">
        <location>
            <begin position="75"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="domain" description="KA1" evidence="12">
        <location>
            <begin position="658"/>
            <end position="708"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="358"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="726"/>
            <end position="754"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="26"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="36"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="358"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="409"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="10">
        <location>
            <begin position="444"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="455"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="735"/>
            <end position="746"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="108"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="OBZ86848.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="754" mass="85382" checksum="696187B260615535" modified="2016-11-30" version="1">MTFVHPLEDHSHGVPDMHHPIRPQQRAHSVTSMPTEKSRTEHQEKKPNQPWWQYYYQLYHYQLPPGRKPTVFGPYLLLQTLGEGEFGKVKFGIEIKTGQEVAIKLIRKDNIDSTSRMTKVEREISVLRILHHPNIVKLFDVIETEKYIGIILQCATGGELFDYILAHRYLKEKDASRLFAQLISGVHYMHQKCIVHRDLKLENLLLDKHRNVLITDFGFANQFSSAQDDLMSTSCGSPCYAAPELVMNQGVYVGPAVDIWSCGVILFAMLCGYLPYDDDPANPESYNINLLYKYILNTPLVFPDYISKEACHLMSLMLVPDPEKRCSMEVIMAHPWLSAHQKVFDQVKETLETKREQVVPDLAVKEVETPPVEPETKHDETPTKDPTNTPTPDKTPHTSLASTEPPAHLQSKFLSSLQKQQQQQQKPPSPSSSPQASASTPHPANKKPSPKRTARLSTVTPPTTTTTTTTERGTRRKTLSLLVNSMTDNRMPFSQHRRQSNAKTAEPVPMMPSVSEHLSALSEKEEKHKSTGKKLMDWFKKKPLSTIQKSNGHETPPASPSTTHFEPKLRIHHGAVDQEALTSRHPTQVFLEVKQTLKSLGLDYKRDGSEFKLKCTRPHKRLAEKRKSIQPQAPPLRMLLRRASASHETSPTIYGDPNVDPGEEVRFSVELCKIKNLPGLYIVDMRRMRGNVWAYKYIYRTLLDTLKLGGKSEYLKTQPTKKVESALLSEVPTANNSSSSSSNSSTKESKKNTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7ND57</accession>
    <name>A0A1C7ND57_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Protein EFR3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">EFR3_0</name>
        <name evidence="3" type="ORF">A0J61_04977</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the EFR3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000256">
        <property type="protein sequence ID" value="OBZ86968.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7ND57"/>
    <dbReference type="FunCoup" id="A0A1C7ND57">
        <property type="interactions" value="1"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7ND57"/>
    <dbReference type="InParanoid" id="A0A1C7ND57"/>
    <dbReference type="OrthoDB" id="19232at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072659">
        <property type="term" value="P:protein localization to plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039786">
        <property type="entry name" value="EFR3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049150">
        <property type="entry name" value="EFR3_HEAT-like_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47766">
        <property type="entry name" value="PROTEIN EFR3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47766:SF1">
        <property type="entry name" value="PROTEIN EFR3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21072">
        <property type="entry name" value="EFR3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="753"/>
            <end position="781"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="796"/>
            <end position="816"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="759"/>
            <end position="770"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="802"/>
            <end position="816"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010216"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ86968.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="816" mass="91771" checksum="52DF13F929C97AC6" modified="2016-11-30" version="1">MSAVTCLPCINIKHATLINNCYPPVKEEKSMPHSSEQSYLLFYASSRPQKLTKVGSFLQKKVARDIRKGRKSHNLVSLHIIKALIQTCHRDLNLFSKYIIAIFSMLLDTRDLDIIDLTCEDFIVFCSYHDGSTLAVDTQFRADYETLLEKFAGFCTYNNNDTLFALKMQYIGHRAIQAAITSSALQSSDFETQLNILFPPLIVTLGSDPKKAMISTSGIDTRISVFDLPTIDNHLIESIAAYTISLLFSKLIASSVRSSLKPLFKYLNETHAWSSPEFAVNMLKLILESLQAQYRYILVSEVMAQIDQMKPDDLTDKHAALVCILDTILNADIPLIGISVLEVQNSIFHLLIRTTPHHPFDPSLAQQDHATTIQHGLVHSMGGLASHTYYDNQLSDMVGYLIPKLKSNTLLEEVEGMPLEAYRVIVLSCLDSVVQGLKKTSASSTWTGSGQVEQEKDTLFLPEGIQAPFDTWTPGLSLLHDKDPKTRIRFSQVLYRFLHAIPVNASAESTHKYPSSSGPLNYLNTANFLTKLAYHLMDWAVLSDFNLSDLKAFYGLLCIANCKFGMDATVLLIPLVFRLQEMIQQETITGKARQEGLLFALIQWLDEIAQFYQIQPMIDYVHPIGSNMYPYRLTELSQSAEDFPDRQPDSFVWIDRTKIVDCMSNHSELRDETDTHGLDLEAKLFAEWDSDAFLQRTQYKRIQITPKPEEHKLKLASPWEDLENKLSFPFNEKSNPSIRVSNLKEALVGQLVADDETDSSQSNSVPSSRSTKATSPPVIKKRTTADLNALLNELSLPHDQSAHSNVSLVNPPYASS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NDP3</accession>
    <name>A0A1C7NDP3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_04782</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000241">
        <property type="protein sequence ID" value="OBZ87178.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NDP3"/>
    <dbReference type="STRING" id="101091.A0A1C7NDP3"/>
    <dbReference type="InParanoid" id="A0A1C7NDP3"/>
    <dbReference type="OrthoDB" id="2290735at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="406"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="454"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="564"/>
            <end position="587"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="605"/>
            <end position="870"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="891"/>
            <end position="972"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1015"/>
            <end position="1038"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="406"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="468"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="566"/>
            <end position="585"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="605"/>
            <end position="617"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="624"/>
            <end position="637"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="638"/>
            <end position="667"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="668"/>
            <end position="685"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="686"/>
            <end position="695"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="696"/>
            <end position="709"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="710"/>
            <end position="723"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="781"/>
            <end position="804"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="859"/>
            <end position="870"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="916"/>
            <end position="946"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="955"/>
            <end position="972"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1018"/>
            <end position="1027"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ87178.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="1278" mass="144349" checksum="27C928BB9CA2D52D" modified="2016-11-30" version="1">MTEYRQLFVKGTKINFDLDPGVLFHYNQDIVEYVYRDPFDYKETVEQLTLADINKRTSKKVEKIQTVLYCRESDSPILVIVASDADKANHIVWYHMDTKKMIDIDSKKAPQGDITAVSITEAPFDVTFKDRQGFYDVRKSSFVMVIGTKQNGTTLILLSLYGPSRIHVELTEPFKPDENNPKELGHVTAICILPPDKEDKRMGHSDLQILLGYSLGSILIYRVRVNVYSYKASRLRGPIDISDFVEFPGYPITQLSCARSYNSLLMTIVLAQEKPPKHKKYQYAQPYIKIVETRGDSTTKQRKIINPASAQIIDTKLIPATTTVDDEELQLAIITQTPDHQLDLNVWEVTPVRSAELLLLSTDQQTCIQRMMHDTTLRLLQLDPAGYLVRMPQKIADVVLKAHGDDIQQRHSDHRLTRSKRKHKLPEPKSKRQKVPYDNSRVIIESEIKLQQMEPLSEETVASEPNVSSSPQTSSTQHPFSHDNALTTMDDVPLDADTQPLTRDQLAGSVEQGELDAMRCSTELQAHAERVAAIETHHDHMDLVTEGAQSDGLALAAEEIALDGTLSEEEVQSDDLSSEQEDDKEETVVETVVETVVETVVETVVEEQMDEQMEEQVEDGREDYVEEQTEEQVEEQVEDHVEEQVEDHVEEQVEDHVEEQVEDHVEEQVEEQVEEQAEEQAEEQAEDGKEYHMEEQMEEEIEEQVEDQAEDHVEEQVENHMDEQVEEQVEEESKPDEIVSEAEIQDGDVSLTTDAHPNDVSLEAGLNANDMPSAVEPESLLSESQAVDMSSASETQHQNASPSVETPLEDIFLQADDQSDTLQDQVASPLLASDSIDPQSPIADKYEDDATPFGATYSDNEEGSEPLYDDYDTFAYDNDNDTLMYERGLDQTEEEESHVILSSDEEDEIHHMDEGNIAEEGYDVQDFDSDGVAGGDDDGSLDESEPEEARQELVITEEDYEEQENNAEAPVEEDQLSSAVALIEDKQQHAVQSSEDTDALMEKKLRNLEQKPFVYGGHLDDEPKPSEPKAASPPAESKIDYIPVSEQDLLRLAPASDIPPQPPLTHADLLLRSLTALNESHQHGRDGTPALSVDTPIATFTDTTASASPASSHSVEEPFVAVNTMSDEDRRAQLIHSIIQGCFGTSEIDIDVLSIDKIEKMGDYCWQQNEPQPKLFMMQYCQQHHMPEAAVLLGRYLLRSQSIMTLDEIKECKSMLRKCMFRVHPIIRKGAIFNPFRLDSQQNLQTQKRDYLKQDKPLLYGSLPQQYTSYYGFGTKSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NDQ4</accession>
    <name>A0A1C7NDQ4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7 8">Multifunctional fusion protein</fullName>
        </recommendedName>
        <domain>
            <recommendedName>
                <fullName evidence="8">Delta-1-pyrroline-5-carboxylate dehydrogenase</fullName>
                <shortName evidence="8">P5C dehydrogenase</shortName>
            </recommendedName>
            <alternativeName>
                <fullName evidence="8">L-glutamate gamma-semialdehyde dehydrogenase</fullName>
            </alternativeName>
        </domain>
        <domain>
            <recommendedName>
                <fullName evidence="7">L-glutamate gamma-semialdehyde dehydrogenase</fullName>
                <ecNumber evidence="7">1.2.1.88</ecNumber>
            </recommendedName>
        </domain>
    </protein>
    <gene>
        <name evidence="10" type="primary">pruA</name>
        <name evidence="10" type="ORF">A0J61_04723</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6 7">
            <text>L-glutamate 5-semialdehyde + NAD(+) + H2O = L-glutamate + NADH + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:30235"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:58066"/>
            <dbReference type="EC" id="1.2.1.88"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 7">Amino-acid degradation; L-proline degradation into L-glutamate; L-glutamate from L-proline: step 2/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the aldehyde dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.2.1.88" evidence="7"/>
    <dbReference type="EMBL" id="LUGH01000237">
        <property type="protein sequence ID" value="OBZ87227.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NDQ4"/>
    <dbReference type="FunCoup" id="A0A1C7NDQ4">
        <property type="interactions" value="209"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NDQ4"/>
    <dbReference type="InParanoid" id="A0A1C7NDQ4"/>
    <dbReference type="OrthoDB" id="5322683at2759"/>
    <dbReference type="UniPathway" id="UPA00261">
        <property type="reaction ID" value="UER00374"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003842">
        <property type="term" value="F:L-glutamate gamma-semialdehyde dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010133">
        <property type="term" value="P:L-proline catabolic process to L-glutamate"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd07123">
        <property type="entry name" value="ALDH_F4-17_P5CDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.605.10:FF:000006">
        <property type="entry name" value="1-pyrroline-5-carboxylate dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.309.10:FF:000005">
        <property type="entry name" value="1-pyrroline-5-carboxylate dehydrogenase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.605.10">
        <property type="entry name" value="Aldehyde Dehydrogenase, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.309.10">
        <property type="entry name" value="Aldehyde Dehydrogenase, Chain A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016161">
        <property type="entry name" value="Ald_DH/histidinol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016163">
        <property type="entry name" value="Ald_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016160">
        <property type="entry name" value="Ald_DH_CS_CYS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016162">
        <property type="entry name" value="Ald_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015590">
        <property type="entry name" value="Aldehyde_DH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005931">
        <property type="entry name" value="P5CDH/ALDH4A1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050485">
        <property type="entry name" value="Proline_metab_enzyme"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01236">
        <property type="entry name" value="D1pyr5carbox1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42862">
        <property type="entry name" value="DELTA-1-PYRROLINE-5-CARBOXYLATE DEHYDROGENASE 1, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42862:SF1">
        <property type="entry name" value="DELTA-1-PYRROLINE-5-CARBOXYLATE DEHYDROGENASE 2, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00171">
        <property type="entry name" value="Aldedh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53720">
        <property type="entry name" value="ALDH-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00070">
        <property type="entry name" value="ALDEHYDE_DEHYDR_CYS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0520">NAD</keyword>
    <keyword evidence="3 7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5 7" id="KW-0642">Proline metabolism</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldehyde dehydrogenase" evidence="9">
        <location>
            <begin position="60"/>
            <end position="523"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009986"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023062"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00048142"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU366016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU366030"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OBZ87227.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="550" mass="59713" checksum="78054DF026C6634C" modified="2016-11-30" version="1">MATPTLAHFKLPQIDNEPMLNYAPGSAERIKLEAAVKDMVAQGTVEVPVVINGEKIFTGKTAEQLNPSNHKSVVAKYHEADATLTQKAIDGALAAKAQWESLPFNDRVAVFLKAADLLSAKYRYKAMAATMLGQGKNIWQAEIDAAAELCDFLRFNCKYAEEIYSQQPPKNAPGTWNRTEFRGLEGFVLAVSPFNFTAIGGNLPAAPALMGNVVIWKPSPGAVLSNYIVYEILVEAGLPAGVIQFVPGPAEEICGHAIASPDFASLHFTGSTHVFRNLWQQIGNNIHKYKSYPRIVGETGGKNYHLLHPSLDEAGVRHAALQTIRGAFEYQGQKCSACSRAYVPASLFAQFKKDLIAEHAKITQGPVTEFHHFSGPVINKFAFDKIKGFIDHAATQDSCEIVAGGKYDDSVGYFIEPTIIVTKDKSAKTLTDEIFGPVLTIYVYEDADFEATCKLVGDTTEYGLTGAFFAKDRASIVAGSNLLRNTAGNFYINDKCTGAVVGQQPFGGGRASGTNDKAGSWSLLVRFVSTRTIKESFVPIENFAYPSNAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NDY9</accession>
    <name>A0A1C7NDY9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="11">DNA mismatch repair protein msh-2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">msh-2</name>
        <name evidence="11" type="ORF">A0J61_04648</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Component of the post-replicative DNA mismatch repair system (MMR).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the DNA mismatch repair MutS family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000232">
        <property type="protein sequence ID" value="OBZ87301.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NDY9"/>
    <dbReference type="FunCoup" id="A0A1C7NDY9">
        <property type="interactions" value="989"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NDY9"/>
    <dbReference type="InParanoid" id="A0A1C7NDY9"/>
    <dbReference type="OrthoDB" id="295033at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032301">
        <property type="term" value="C:MutSalpha complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032302">
        <property type="term" value="C:MutSbeta complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000228">
        <property type="term" value="C:nuclear chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140664">
        <property type="term" value="F:ATP-dependent DNA damage sensor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000406">
        <property type="term" value="F:double-strand/single-strand DNA junction binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000400">
        <property type="term" value="F:four-way junction DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032137">
        <property type="term" value="F:guanine/thymine mispair binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000404">
        <property type="term" value="F:heteroduplex DNA loop binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032138">
        <property type="term" value="F:single base insertion or deletion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000403">
        <property type="term" value="F:Y-form DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007534">
        <property type="term" value="P:gene conversion at mating-type locus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036297">
        <property type="term" value="P:interstrand cross-link repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043570">
        <property type="term" value="P:maintenance of DNA repeat elements"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006311">
        <property type="term" value="P:meiotic gene conversion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000710">
        <property type="term" value="P:meiotic mismatch repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000735">
        <property type="term" value="P:removal of nonhomologous ends"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043111">
        <property type="term" value="P:replication fork arrest"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030466">
        <property type="term" value="P:silent mating-type cassette heterochromatin formation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd03285">
        <property type="entry name" value="ABC_MSH2_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.110:FF:000002">
        <property type="entry name" value="DNA mismatch repair protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000523">
        <property type="entry name" value="DNA mismatch repair protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1420.10:FF:000017">
        <property type="entry name" value="DNA mismatch repair protein Msh2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1420.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1170.10">
        <property type="entry name" value="DNA repair protein MutS, domain I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.110">
        <property type="entry name" value="MutS, connector domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011184">
        <property type="entry name" value="DNA_mismatch_repair_Msh2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007695">
        <property type="entry name" value="DNA_mismatch_repair_MutS-lik_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000432">
        <property type="entry name" value="DNA_mismatch_repair_MutS_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007861">
        <property type="entry name" value="DNA_mismatch_repair_MutS_clamp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007696">
        <property type="entry name" value="DNA_mismatch_repair_MutS_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016151">
        <property type="entry name" value="DNA_mismatch_repair_MutS_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036187">
        <property type="entry name" value="DNA_mismatch_repair_MutS_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007860">
        <property type="entry name" value="DNA_mmatch_repair_MutS_con_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032642">
        <property type="entry name" value="Msh2_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045076">
        <property type="entry name" value="MutS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036678">
        <property type="entry name" value="MutS_con_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003810">
        <property type="entry name" value="PRK05399.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11361:SF35">
        <property type="entry name" value="DNA MISMATCH REPAIR PROTEIN MSH2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11361">
        <property type="entry name" value="DNA MISMATCH REPAIR PROTEIN MUTS FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01624">
        <property type="entry name" value="MutS_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05188">
        <property type="entry name" value="MutS_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05192">
        <property type="entry name" value="MutS_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05190">
        <property type="entry name" value="MutS_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00488">
        <property type="entry name" value="MutS_V"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005813">
        <property type="entry name" value="MSH2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00534">
        <property type="entry name" value="MUTSac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00533">
        <property type="entry name" value="MUTSd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53150">
        <property type="entry name" value="DNA repair protein MutS, domain II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48334">
        <property type="entry name" value="DNA repair protein MutS, domain III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00486">
        <property type="entry name" value="DNA_MISMATCH_REPAIR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 9" id="KW-0227">DNA damage</keyword>
    <keyword evidence="7 9" id="KW-0234">DNA repair</keyword>
    <keyword evidence="6 9" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA mismatch repair proteins mutS family" evidence="10">
        <location>
            <begin position="746"/>
            <end position="762"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006271"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU003756"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS00486"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="OBZ87301.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="930" mass="105191" checksum="EAF163712C7BD02A" modified="2016-11-30" version="1">MSKTAAVEDLPDVEKPEQQNFVKFFRALEAPEEHTIRLFEREANDAAYYTCHGDDAHYVAQQVFETTSVIKYWFGDSETGLPTTKLTNNVAETFMRDVLLNKQLKIEIWKQQRLEWQLQRKASPGNLQSVEDILFSNKQLTSAPVVIAVKYSISGDQKIVGVAFADTTIHQLGVSQFADNELYSNLESLVIQLGVKECLLMHAEKDYESTKIRSILDRCDVVVTERKKNEFDAKNITQDLNRLLESETAIEALPELDMKDAMASCACVIKYLQLLDNESNFSRFTLKHHDLSQYMRLDGPALAALNLMPTAKDGPHKSTNVYGLLNKCCTAQGSRLFAQWLKQPLLNIEEIILYEAERQDIVQAFCDDTETRQAIQEDHLKHVPDLHRLAKRFQKGLATLQDVVRIYQVVIRLPAFVECLEARPNPDSKIAALIERTYTSLIREYAGILQKLEELVVTTIDLEALENHEYIIKAEFNEELQALHTSLQKTDKEMNMEYQKVSDKLNLEMDKKLKLEKHSLYGYCFRIVGRTEASKLRNKSEYMELSTQKSGTFFRSHKLKELNESHSTLSKEYEEKQRGLVKEVLDITATYCPTLEALGSVLAHLDVLVSFAHVSVMAPIPYVRPTMYPCGQGDVILEEARHPCLEVQDYVSFIPNDVHMIRETSEFQIITGPNMGGKSTYIRQVGVIALMAQIGCFVPCTKASLCVFDSILARVGAGDSQLKGVSTFMAEMMETSTILKAASRNSLVIIDELGRGTSTYDGLGLAWAISEYIATKIHAFCMFATHFHELTTLAETQKHVKNLHVAVHVGDDHEVTLLYKVKEGFGDRSFGIHVAELAKFPKSVVDLAKRKADELDYEADMLRGAQKPKVEAVSEGETLMETIIKEMATAATAVDAEDQIDAIKKRYQADIERNDYLRELLITNNPYNTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NE23</accession>
    <name>A0A1C7NE23_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Vacuolar protein sorting-associated protein 45</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">Vps45</name>
        <name evidence="2" type="ORF">A0J61_04942</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the STXBP/unc-18/SEC1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000253">
        <property type="protein sequence ID" value="OBZ87019.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NE23"/>
    <dbReference type="FunCoup" id="A0A1C7NE23">
        <property type="interactions" value="454"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NE23"/>
    <dbReference type="InParanoid" id="A0A1C7NE23"/>
    <dbReference type="OrthoDB" id="10266265at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016192">
        <property type="term" value="P:vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1910">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2060">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.830.10">
        <property type="entry name" value="Syntaxin Binding Protein 1, Chain A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043154">
        <property type="entry name" value="Sec-1-like_dom1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043127">
        <property type="entry name" value="Sec-1-like_dom3a"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001619">
        <property type="entry name" value="Sec1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027482">
        <property type="entry name" value="Sec1-like_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036045">
        <property type="entry name" value="Sec1-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11679">
        <property type="entry name" value="VESICLE PROTEIN SORTING-ASSOCIATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00995">
        <property type="entry name" value="Sec1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005715">
        <property type="entry name" value="VPS45_Sec1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56815">
        <property type="entry name" value="Sec1/munc18-like (SM) proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ87019.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="560" mass="64169" checksum="39E1B21F01CCCD25" modified="2016-11-30" version="1">MDVIKAIQNYADRMLNDVPGMKALLLDTETTPIISLATTQSHLLTKECYLIDRIDNRNRDKMKHLKCICFLRPTRETLQYLIAELREPAYGDYYLYFSNTLRKSDIEQLAEVDEHEVIREVQEYYGDYLAINPDLFSLGQDSRYLFGNTAQSWDEDSYEQSVKGLCAVLLSLKKKPVIRYEGKSAMAKRLALGIQQTIQTEGPLFDFRRPDAPPILLILDRKNDPVTPLLTQWTYQAMVHELIGIHHGRVDMTHVPEIKHELKEIVLCPDQDPFFKKSMYLNLGDLGATIKQYVDEYQTKTKSNMNIESIADMKRFVEEYPEFRKLSGNVSKHVALVSELSRRVSQSHLLEISELEQGLACNENHQSDLRHIQQLIASPDIDQEAKIRLVLLYALRYERLANNSIKSLISLLDQHGVSERKSALIPAILFYAGYQQRQDDLFSNQSFLSRGKSALKGLKGVENVYTQHTPHLGETLDLLIKARLRDTEYPFTTPQTLMERPQDIIVFICGGATYEEARYIAQLNATVPGVRIVLGGNCVHNSRTFMNQVEQIGTKFMNLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NEG7</accession>
    <name>A0A1C7NEG7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">TEA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">A0J61_04506</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TEC1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000222">
        <property type="protein sequence ID" value="OBZ87438.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NEG7"/>
    <dbReference type="STRING" id="101091.A0A1C7NEG7"/>
    <dbReference type="InParanoid" id="A0A1C7NEG7"/>
    <dbReference type="OrthoDB" id="10006572at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005667">
        <property type="term" value="C:transcription regulator complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.50.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.20.40">
        <property type="entry name" value="TEA/ATTS domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000818">
        <property type="entry name" value="TEA/ATTS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038096">
        <property type="entry name" value="TEA/ATTS_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050937">
        <property type="entry name" value="TEC1_TEAD_TF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041086">
        <property type="entry name" value="YBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11834:SF0">
        <property type="entry name" value="PROTEIN SCALLOPED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11834">
        <property type="entry name" value="TRANSCRIPTIONAL ENHANCER FACTOR TEF RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01285">
        <property type="entry name" value="TEA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17725">
        <property type="entry name" value="YBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00065">
        <property type="entry name" value="TEADOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00426">
        <property type="entry name" value="TEA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51088">
        <property type="entry name" value="TEA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="TEA" evidence="9">
        <location>
            <begin position="60"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="TEA" evidence="7">
        <location>
            <begin position="60"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="296"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="298"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="314"/>
            <end position="334"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008421"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00505"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51088"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OBZ87438.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="664" mass="75106" checksum="CA13FEF526BCD2BF" modified="2016-11-30" version="1">MLAYAQDIFFSTELSAASDMNDCQMNERRVQQQKILKNNDTLLHLPTQSLTSHDHVPNKEKEEQQVWPPDVEAAFIEALETIPKLGRRKILVNGKPCGRNELISDFIYRKTGKIRTRKQVSSHIQVLKNTRKSDLHFMRLLTDSVEDEGFASSSASLIKKPKQTMSRRQSNLQLRQHQNQLNPIMRSSESFSSDDSSISSSSPADYVVDFMCHEQQMASLSMHDSIYDSMFNIDSSLANTQQHAITKSTNAVNNSFSLHSFGDADANEVLQHLFPLTDSTTGSNPNVIDILLQPSPPQQQQQNHYPSLPQQMHYKSKKKSNGPRKYTKRQKKYMQSHQPYQPYQYNILNEFASSLSLSSATSHSNLSGNNYIDPSLHPLWPTYICLYLDQTNPYEQTVPVPHTLAILPDCMPYHIPTIDLPFVAKNKCPPVSDIVQYGSVTTLSAKVELNLDMNLNDFAFNNASFFETHERRTIECTTTIYSFGKVVLESKEVQQALWINEGKFVYNFAYVNQFFDAFMKGIRSLQSWEEIDIAINNLCVVQVFEDVESSINQQQQQVVENLMLAPPHTPTGSSTAPTTPVAVAINDPMATSLNDLQQETADNLMLSTDTNNLLMPEFAPLLVMIYEFERGQGSIGISMVKNHSKNFDFLTNNAPNIPLSTTDM</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NEN4</accession>
    <name>A0A1C7NEN4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_04544</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000225">
        <property type="protein sequence ID" value="OBZ87410.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NEN4"/>
    <dbReference type="InParanoid" id="A0A1C7NEN4"/>
    <dbReference type="OrthoDB" id="2261102at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ87410.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="79" mass="8893" checksum="FD194CCC00D6F429" modified="2016-11-30" version="1">MISRIFSACRNTSIQRPVQQQSRHSLEDSSEEFVRATQTTKAIQIPSLSTSTATLAYFGLSYNNADDFIQKDLISNSLY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NF54</accession>
    <name>A0A1C7NF54_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_04273</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000205">
        <property type="protein sequence ID" value="OBZ87678.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NF54"/>
    <dbReference type="InParanoid" id="A0A1C7NF54"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="47"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="47"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ87678.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="140" mass="15220" checksum="7F4AF14B6FB1ED50" modified="2016-11-30" version="1">MNICCKIQSEKKSQPIPSKGNHVCLQEAMSAPASYIDQVPKSIPISIPSKIQSGSKQSSQSVPTNSMTTVCSTSLSFDTEESIPSENRVSFIVGSIVDKQPIPWPSFLTTPYDLKENGALHLKNESRSGTPISDEVFTMD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NFV6</accession>
    <name>A0A1C7NFV6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Charged multivesicular body protein 5</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">Chmp5</name>
        <name evidence="4" type="ORF">A0J61_04059</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SNF7 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000190">
        <property type="protein sequence ID" value="OBZ87898.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NFV6"/>
    <dbReference type="FunCoup" id="A0A1C7NFV6">
        <property type="interactions" value="348"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NFV6"/>
    <dbReference type="InParanoid" id="A0A1C7NFV6"/>
    <dbReference type="OrthoDB" id="3973241at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000329">
        <property type="term" value="C:fungal-type vacuole membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005771">
        <property type="term" value="C:multivesicular body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032511">
        <property type="term" value="P:late endosome to vacuole transport via multivesicular body sorting pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006900">
        <property type="term" value="P:vesicle budding from membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.1710">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.1060">
        <property type="entry name" value="ESAT-6-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005024">
        <property type="entry name" value="Snf7_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22761">
        <property type="entry name" value="CHARGED MULTIVESICULAR BODY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22761:SF12">
        <property type="entry name" value="CHARGED MULTIVESICULAR BODY PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03357">
        <property type="entry name" value="Snf7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="176"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="176"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="191"/>
            <end position="208"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OBZ87898.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="224" mass="25746" checksum="FC48F2907A2AE360" modified="2016-11-30" version="1">MNRLFGSGKKVPKPTLNDAIANTDVRVDAVEVKIRKLDAELTRYRDQLKKMREGPAKKNVQQKALRVLKQKKLYESQRDNLQQQSFNMEQAQMTTENLRNVMATVDAMQTANKEMKKQYKNVNLDKIDQLQDEMEDLMEQANEVQETLGRSYNLPDDIDEDDLEAELDALGDELEFEDEEIPSYLQEDELELPKISETDPSKAHQDVKLDEFGLPVAAEAPMKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NFZ7</accession>
    <name>A0A1C7NFZ7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">NADH-ubiquinone oxidoreductase subunit, mitochondrial</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">nuo-49</name>
        <name evidence="7" type="ORF">A0J61_04061</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the complex I 49 kDa subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000190">
        <property type="protein sequence ID" value="OBZ87890.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NFZ7"/>
    <dbReference type="STRING" id="101091.A0A1C7NFZ7"/>
    <dbReference type="InParanoid" id="A0A1C7NFZ7"/>
    <dbReference type="OrthoDB" id="1009at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016651">
        <property type="term" value="F:oxidoreductase activity, acting on NAD(P)H"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048038">
        <property type="term" value="F:quinone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006120">
        <property type="term" value="P:mitochondrial electron transport, NADH to ubiquinone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.645.10:FF:000005">
        <property type="entry name" value="NADH-quinone oxidoreductase subunit D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.645.10">
        <property type="entry name" value="Cytochrome-c3 Hydrogenase, chain B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01358">
        <property type="entry name" value="NDH1_NuoD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001135">
        <property type="entry name" value="NADH_Q_OxRdtase_suD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014029">
        <property type="entry name" value="NADH_UbQ_OxRdtase_49kDa_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022885">
        <property type="entry name" value="NDH1_su_D/H"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029014">
        <property type="entry name" value="NiFe-Hase_large"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01962">
        <property type="entry name" value="NuoD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF004739">
        <property type="entry name" value="PRK06075.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11993:SF10">
        <property type="entry name" value="NADH DEHYDROGENASE [UBIQUINONE] IRON-SULFUR PROTEIN 2, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11993">
        <property type="entry name" value="NADH-UBIQUINONE OXIDOREDUCTASE 49 KDA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00346">
        <property type="entry name" value="Complex1_49kDa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56762">
        <property type="entry name" value="HydB/Nqo4-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00535">
        <property type="entry name" value="COMPLEX1_49K"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0520">NAD</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-1278">Translocase</keyword>
    <keyword evidence="2 5" id="KW-0813">Transport</keyword>
    <keyword evidence="7" id="KW-0830">Ubiquinone</keyword>
    <feature type="domain" description="NADH-quinone oxidoreductase subunit D" evidence="6">
        <location>
            <begin position="190"/>
            <end position="460"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005769"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OBZ87890.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="460" mass="52478" checksum="E241634CC058E6C0" modified="2016-11-30" version="1">MSFATRMWSRKFANVAATATKSTLLKPRMPLKTFQPMRTLATATQQTVAYTPTTITEDHTDSEFGAADDEESRMRNFTVNFGPQHPAAHGVLRLILEMNGEEIVRADPHIGLLHRGTEKLIEYKNYLQALPYFDRLDYVSIMTNEQAYSLAVEKLLNIEVPERAKYIRTMFGEITRVLNHIMAVMTHAMDVGALTPMLWMFEEREKLMEFYERCSGARLHAAYVRPGGVAYDLPIGLLQDIHDWCEQFGDRVDEVEELLTGNRIWHIRTRNVGVVTAKEAQDWGFSGVLVRGSGIPWDLRKVAPYDAYDKVEFDVPVGQNGDCFDRYLCRMEEMRQSLRIIHQCVNKMPEGPIKTDDWKITPPPRAAMKENMEALIHHFKLFSEGFSVPAGETYTVIEAPKGEFGVFLVSDGTNRPYRCKIRSPGFSHLQGSDFMSRNHLLPDMVTIIGTQDIVFGEVDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NGU9</accession>
    <name>A0A1C7NGU9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Adhesin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_05354</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000286">
        <property type="protein sequence ID" value="OBZ86604.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NGU9"/>
    <dbReference type="STRING" id="101091.A0A1C7NGU9"/>
    <dbReference type="InParanoid" id="A0A1C7NGU9"/>
    <dbReference type="OrthoDB" id="2287180at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ86604.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="209" mass="22906" checksum="6172CDC5146F0BEF" modified="2016-11-30" version="1" fragment="single">SEEKDDDYVIKLKSEKVNINHACARLDLTIRTPTKEALKGLTLKLGNTDVTLDKDLVFETKLDIYVANGHIDFKKGITSGKTAFGIANGEIVGQVHTLLSNELHTSIANGHTDIVVGEIKQDLKSVNIKSSMSNGHIRLQLPVSFESRFSIKGFSGKKQVQSPEANKIHYLGRRWGLVSGYFGDRSDIDHTVDLSGANGAITLLYQNVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NH18</accession>
    <name>A0A1C7NH18_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_03547</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000154">
        <property type="protein sequence ID" value="OBZ88412.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NH18"/>
    <dbReference type="STRING" id="101091.A0A1C7NH18"/>
    <dbReference type="InParanoid" id="A0A1C7NH18"/>
    <dbReference type="OrthoDB" id="2273980at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ88412.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="155" mass="17644" checksum="58D26D227097C967" modified="2016-11-30" version="1">MDQSRSTSVPLLTLGDDFGELMKSSYSLPSIQAPSFQLVSDILSHDESELDTASRSQSLDDNESMWSSSSENEIGIAIHGRKASQSVRPFAMNALSSDLLYEDIWADSPAFHDYLHQLKGCLYHFIIWLEKLEHCRQLEMGKKDSIENIFLRERE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NH48</accession>
    <name>A0A1C7NH48_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">PH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_03595</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000157">
        <property type="protein sequence ID" value="OBZ88365.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NH48"/>
    <dbReference type="InParanoid" id="A0A1C7NH48"/>
    <dbReference type="OrthoDB" id="2261218at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001849">
        <property type="entry name" value="PH_domain"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50003">
        <property type="entry name" value="PH_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PH" evidence="2">
        <location>
            <begin position="312"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="57"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="70"/>
            <end position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ88365.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="470" mass="54495" checksum="4605359CBAD9889C" modified="2016-11-30" version="1">MSAYKTLKNPLLEDISSTAHKKVHAFKRSNLSFKDFLHSPTVRFQNSLNNRKIVPSTLSKSKGNEAGHHSQQQLQQSQSRPLQKQNRNRTKGRREQNEPLIHYNGPYETLDELPEEKSKWIVTETSDNEELRHPVLDYPRSIVLRKPHYRNSSSLGYYISNDQPAISKARATFYIRVLQVINKSSSKTCFIRSSVEVNDQVFTGSYAISQKCGKHGSQANLDETYILDVDKFSVAILSIYAQPKTALSVLNSRFNQPEVCLGTQEFKIPMRPFEKKLKRISILDKNTHDQYQVLVVFGTYVSSRVMTLXDNKRIYEGFLTVYTKGKLIPRWARYWAVLYPGHIELYDFEYKERKDPLYRISIKALLDVFHPPTDDDERLVDVGSLGLALQFSKESLLDDKIVNVDFEYRMYILPDDQERSQEWEKALLHAASLINEFRYDENYNATNTKQNSQDQDAGINTLIISSKFLW</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NHR1</accession>
    <name>A0A1C7NHR1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Small acidic protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">A0J61_03286</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SMAP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000139">
        <property type="protein sequence ID" value="OBZ88647.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NHR1"/>
    <dbReference type="InParanoid" id="A0A1C7NHR1"/>
    <dbReference type="OrthoDB" id="10066125at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026714">
        <property type="entry name" value="SMAP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028124">
        <property type="entry name" value="SMAP_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22175:SF0">
        <property type="entry name" value="SMALL ACIDIC PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22175">
        <property type="entry name" value="SMALL ACIDIC PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15477">
        <property type="entry name" value="SMAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Small acidic protein-like" evidence="4">
        <location>
            <begin position="93"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="17"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="78"/>
            <end position="89"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00016161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF15477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OBZ88647.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="180" mass="20769" checksum="76BE9E99B7A1A4F6" modified="2016-11-30" version="1">MSKKEKIVDTTVEKKEKKEKKEKKEKKEKKEKKEKKEKKEKREKKEKKRKHSESESEEEFIIHENFHAKKTKVAETTPVKQQETQNTGGWNDWSKASFDGDDAKKNKFLRLLGAKKSNAPAFVPASTNTKKSGGLYGGLKSAIDQDENAKISHMLEKQFDHGLQFKKQMQMGRRGGLGFN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NI89</accession>
    <name>A0A1C7NI89_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Decarboxylase NovR</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">novR</name>
        <name evidence="2" type="ORF">A0J61_03464</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000150">
        <property type="protein sequence ID" value="OBZ88479.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="FunCoup" id="A0A1C7NI89">
        <property type="interactions" value="2"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NI89"/>
    <dbReference type="InParanoid" id="A0A1C7NI89"/>
    <dbReference type="OrthoDB" id="3238794at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005856">
        <property type="term" value="C:cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051015">
        <property type="term" value="F:actin filament binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.225.10:FF:000009">
        <property type="entry name" value="Class II aldolase/adducin N-terminal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.225.10">
        <property type="entry name" value="Class II aldolase/adducin N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051017">
        <property type="entry name" value="Aldolase-II_Adducin_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001303">
        <property type="entry name" value="Aldolase_II/adducin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036409">
        <property type="entry name" value="Aldolase_II/adducin_N_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF004855">
        <property type="entry name" value="PRK06208.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10672">
        <property type="entry name" value="ADDUCIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10672:SF39">
        <property type="entry name" value="CLASS II ALDOLASE_ADDUCIN N-TERMINAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00596">
        <property type="entry name" value="Aldolase_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01007">
        <property type="entry name" value="Aldolase_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53639">
        <property type="entry name" value="AraD/HMP-PK domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Class II aldolase/adducin N-terminal" evidence="1">
        <location>
            <begin position="62"/>
            <end position="243"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM01007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ88479.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="297" mass="33345" checksum="1A5672DE614FBDD7" modified="2016-11-30" version="1">MTVENNKQPHERSTIFLRSKRKIILTGSETEEEAREAEKQNVVIPRLPVFQDVHTERVRMKQKLAAGFRLLAKFGWDEGVAGHMTFRDPEYPDLFWVNPFGRYFGHLKASDLILVDHEGAIVRGGYTVNKAAFVIHAAIHKARPDITCAVHTHSIYGRTFSTLGRPLLPISQDACAFYGVHGVYEDFGGVVFDEEEGKRLTKALGPTHKALILQNHGLLTTGKTVDEAIWAFISMEXCCHSQLMAEAAHPNGYKDLKVIDDQTATATFKIVGDSVAGYMQFQPMYEMIVKEQPDCLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NIR7</accession>
    <name>A0A1C7NIR7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 9">Geranylgeranyl transferase type-2 subunit alpha</fullName>
            <ecNumber evidence="2 9">2.5.1.60</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7 9">Geranylgeranyl transferase type II subunit alpha</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="primary">bet4</name>
        <name evidence="10" type="ORF">A0J61_02959</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Catalyzes the transfer of a geranyl-geranyl moiety from geranyl-geranyl pyrophosphate to cysteines occuring in specific C-terminal amino acid sequences.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8 12">
            <text>geranylgeranyl diphosphate + L-cysteinyl-[protein] = S-geranylgeranyl-L-cysteinyl-[protein] + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:21240"/>
            <dbReference type="Rhea" id="RHEA-COMP:10131"/>
            <dbReference type="Rhea" id="RHEA-COMP:11537"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57533"/>
            <dbReference type="ChEBI" id="CHEBI:86021"/>
            <dbReference type="EC" id="2.5.1.60"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 9">Belongs to the protein prenyltransferase subunit alpha family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.60" evidence="2 9"/>
    <dbReference type="EMBL" id="LUGH01000119">
        <property type="protein sequence ID" value="OBZ89001.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NIR7"/>
    <dbReference type="FunCoup" id="A0A1C7NIR7">
        <property type="interactions" value="72"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NIR7"/>
    <dbReference type="InParanoid" id="A0A1C7NIR7"/>
    <dbReference type="OrthoDB" id="1658at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005968">
        <property type="term" value="C:Rab-protein geranylgeranyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004663">
        <property type="term" value="F:Rab geranylgeranyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097354">
        <property type="term" value="P:prenylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.120:FF:000035">
        <property type="entry name" value="Geranylgeranyl transferase type-2 subunit alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.120">
        <property type="entry name" value="Protein prenylyltransferase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002088">
        <property type="entry name" value="Prenyl_trans_a"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11129:SF2">
        <property type="entry name" value="GERANYLGERANYL TRANSFERASE TYPE-2 SUBUNIT ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11129">
        <property type="entry name" value="PROTEIN FARNESYLTRANSFERASE ALPHA SUBUNIT/RAB GERANYLGERANYL TRANSFERASE ALPHA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01239">
        <property type="entry name" value="PPTA"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48439">
        <property type="entry name" value="Protein prenylyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51147">
        <property type="entry name" value="PFTA"/>
        <property type="match status" value="5"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 9" id="KW-0637">Prenyltransferase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0677">Repeat</keyword>
    <keyword evidence="5 9 10" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006734"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012656"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00014772"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022602"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00031267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00047658"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU367120"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OBZ89001.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="501" mass="59162" checksum="7F6B793F18AD44C1" modified="2016-11-30" version="1">MSDVHGKKREKTTEEVIRARRQKEAVKIKEYNQLVEKIRTKMNDKAYDDEAFSLTTQIVQWNSDHYTIWNYRRVILLEHVLKQLDLEQQQKTYQKELLLFMQLIQSNPKSYWLWNHRFWCLQHMPTPDWQAELALVEKMLTLDARNFHGWNYRRYVVSHLRKQAKDEHELTAIVKNEYEFTTRKINQSFSNYSAWHQRSKLLPEIVMDMTEEERNQVAIHELDLVKNAIYTDPEDQSAWLYYWWLLGRAPDHVECIGAYALQDDPSIIYVGLNDSVKWLAAPSLAHVSTKLYPLCSRDKESASTWALVMDSTTADYPQKLIIQSNTVLPSTSAKSVPQDTLWEMEIKRIAQPSALQKHLAQLQPFQDEWKPTSSRLYDDPTLQDQSSWFSLDKTQLLKDEIAVVRELLEIEPESAWALQTLVHFLSQLQLRSQHEDTMDAEIIDILDKLIEIDSDRKQRYKDQKTKILFDQATRQSKTEAYEFDLIHPEPQTCLLSKLLFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NJ85</accession>
    <name>A0A1C7NJ85_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_02777</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000109">
        <property type="protein sequence ID" value="OBZ89171.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NJ85"/>
    <dbReference type="InParanoid" id="A0A1C7NJ85"/>
    <dbReference type="OrthoDB" id="2429891at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="29"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="29"/>
            <end position="40"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ89171.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="209" mass="24497" checksum="CF1417D1149586B1" modified="2016-11-30" version="1">MLSRRFLSVFSTPRYVRFSSSSSCNNKLQLESADTQTSTTADKEKKETSTEKIHFMPVINIPETELAHHAFFSLHRPLLGLSDDERPFFSGKSTEEYNQDKLDMELQDYLLDRQPFDTPLPPGQKTIEPKTEITIELEQEVMIDDSFEDIRQEPIPVFHMPESNDILDFLSTVENKLKREHDVLEAKESRQRKIEMIKRFHAAKRRHNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NJL8</accession>
    <name>A0A1C7NJL8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Sulfate transporter CysZ</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">A0J61_02940</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000118">
        <property type="protein sequence ID" value="OBZ89009.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NJL8"/>
    <dbReference type="STRING" id="101091.A0A1C7NJL8"/>
    <dbReference type="InParanoid" id="A0A1C7NJL8"/>
    <dbReference type="OrthoDB" id="10012223at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059112">
        <property type="entry name" value="CysZ/EI24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052786">
        <property type="entry name" value="Spore_wall_assembly"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34292">
        <property type="entry name" value="OUTER SPORE WALL PROTEIN LDS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34292:SF2">
        <property type="entry name" value="OUTER SPORE WALL PROTEIN LDS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07264">
        <property type="entry name" value="EI24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="26"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="69"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="138"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="205"/>
            <end position="227"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OBZ89009.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="284" mass="32602" checksum="66A7F5291FC12FEC" modified="2016-11-30" version="1">MNKKFAPAFTFPFRGIWFLIRHPKQLWLKTLSPILLTILFSAFSIGFSIKYLLPGLANKMISWHWPHWMSWFVSIISTVLEGAIINLIFFAFLVPIFQDSVFDATLKARGLERIFEEEEERDIPKLVVCWRNMRSSILVTWILITIKILLLVLTAPLQLVPVVGNALACTINGWPTAWNLRLHYDIELRGYKVSESYHHARDNKWTYVSMGAAAFALELIPLFNIIFTWTNIVGAGLWVADEYERENTLVTNDSKDRSIIYPVAQAPTTSAASDERTPLLQQSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NJQ7</accession>
    <name>A0A1C7NJQ7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_04431</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000217">
        <property type="protein sequence ID" value="OBZ87514.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NJQ7"/>
    <dbReference type="InParanoid" id="A0A1C7NJQ7"/>
    <dbReference type="OrthoDB" id="2246723at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="433"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="433"/>
            <end position="480"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ87514.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="503" mass="58612" checksum="1C2DDF36AC45FE2D" modified="2016-11-30" version="1">MTFVGKTELEKFISQSEDFTLGSFLNKHEAIVVSTNNYKSHLHLRAVWIKRYRAVFKANKANHVRKVKSYTIVPEAKWRELHHKNKKEAITSHATDDVRSVLMEWCFNEMEGVDGLETKRRQYIAKASALIDERTCLLDRLSYELLKIFNDLRKTEVEVLKLSLSGVINISSLEYKEVMKKHLQQDFYEEIAALKHTCCLETDKQQAIEGEARKDDPNFGVEVGKNATTMENQIRLVFQYLFLHLESYKKRKAEYNFVSLIDNVFLNILNDTEIEMHPGETECFATKETMLNNETSFSSSSSSKKVNGRKIDILVKTGSCKELCAIEFKRNTEKKQKTSKKRSRRPESKSIRINKCILNQLQKEGSPCKFILGLDFTGMSGYLYALLPYKQLYVTVLVREVEIPSNRSELQKDKLLNVLLAFYELKEFWLSVEEEEAPEEDEEDEEDEKDKDEEDKEDEDKEDKEDKEDEDKEDEDGDDDESRKLIVDNTVFFTPRLASKKLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NJY9</accession>
    <name>A0A1C7NJY9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Actin-related protein 2/3 complex subunit 3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">arc3</name>
        <name evidence="7" type="ORF">A0J61_02471</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Component of the Arp2/3 complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Cytoplasm</location>
            <location evidence="1 6">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the ARPC3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000094">
        <property type="protein sequence ID" value="OBZ89461.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NJY9"/>
    <dbReference type="FunCoup" id="A0A1C7NJY9">
        <property type="interactions" value="239"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NJY9"/>
    <dbReference type="InParanoid" id="A0A1C7NJY9"/>
    <dbReference type="OrthoDB" id="200404at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030479">
        <property type="term" value="C:actin cortical patch"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005885">
        <property type="term" value="C:Arp2/3 protein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051015">
        <property type="term" value="F:actin filament binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044396">
        <property type="term" value="P:actin cortical patch organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034314">
        <property type="term" value="P:Arp2/3 complex-mediated actin nucleation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006897">
        <property type="term" value="P:endocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051654">
        <property type="term" value="P:establishment of mitochondrion localization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007163">
        <property type="term" value="P:establishment or maintenance of cell polarity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030833">
        <property type="term" value="P:regulation of actin filament polymerization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1760.10">
        <property type="entry name" value="Actin-related protein 2/3 complex subunit 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007204">
        <property type="entry name" value="ARPC3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036753">
        <property type="entry name" value="ARPC3_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12391">
        <property type="entry name" value="ARP2/3 COMPLEX 21 KD SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04062">
        <property type="entry name" value="P21-Arc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016315">
        <property type="entry name" value="ARP2/3_P21-Arc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69060">
        <property type="entry name" value="Arp2/3 complex 21 kDa subunit ARPC3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0009">Actin-binding</keyword>
    <keyword evidence="3 6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 6" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010856"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRNR" id="PIRNR016315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OBZ89461.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="172" mass="19929" checksum="C323384FBD175450" modified="2016-11-30" version="1">MPAYHSQFNEGDYQSVGNMFLLPIKTKYRGNAPYADPNTEDIIDEALDLFRANCLFRNFEIKGNADRVLIYLILFISQCLGSLNKMTPQSEAFKSLSTLAVSNFSIPSDPAFPLNAMYQAPTDKFQAEQMKQYMQQLRQELVLRLVDRIYVDGHLSKWWMCFSKRKFMNLSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NK13</accession>
    <name>A0A1C7NK13_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Protein GUCD1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">Gucd1</name>
        <name evidence="1" type="ORF">A0J61_04325</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000210">
        <property type="protein sequence ID" value="OBZ87614.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NK13"/>
    <dbReference type="InParanoid" id="A0A1C7NK13"/>
    <dbReference type="OrthoDB" id="206796at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.70.10">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018616">
        <property type="entry name" value="GUCD1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31400">
        <property type="entry name" value="GUANYLYL CYCLASE DOMAIN CONTAINING PROTEIN 1 GUCD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31400:SF1">
        <property type="entry name" value="PROTEIN GUCD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09778">
        <property type="entry name" value="Guanylate_cyc_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ87614.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="246" mass="28354" checksum="F216A3D1FA026D9A" modified="2016-11-30" version="1">MISLGTDDRMQSLTTDIMINYSDFSDHPIPHINQDANWDCGLACVVMILRGLGFNVSIEDMTRQCPVNSVWTIDLAFLLRNYVQDFTYYTSYLGSRREYQDQKFYQDSFGEDEKRVNKLFAIAKSCSVHVVRMMLPLDDFKRFLYCKQFAILTLVNARLLQCQLCKQRQGCLGSMCGQLDLLLERFKGYEYLGHFIILIGYDPTEDLFVYRDPAIDDAFCTISADDLDKARQSEGTDHDCIVVKLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NK76</accession>
    <name>A0A1C7NK76_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_02406</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000090">
        <property type="protein sequence ID" value="OBZ89542.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NK76"/>
    <dbReference type="STRING" id="101091.A0A1C7NK76"/>
    <dbReference type="InParanoid" id="A0A1C7NK76"/>
    <dbReference type="OrthoDB" id="2291034at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="89"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="97"/>
            <end position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ89542.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="182" mass="20439" checksum="EC9A2675945165F3" modified="2016-11-30" version="1">MVHHKAASCSAIPSYDTFQRKSSSRFESDSRLFPLPSFCLYSKQALNNEHGSDSDIIQFVSPASDLLEEKLPMFAGVLQSLVTVVNEMPTVKRTNQDDDEEDEEEVDTTPSNTVPYHIIGLSTMKLILWYLSDLCLIVFVSSSHTDDDLLQAMTDIKESLGEWTTAEELGNQLTPLISDRFQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NKC1</accession>
    <name>A0A1C7NKC1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Interferon-inducible GTPase 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">Iigp1_1</name>
        <name evidence="7" type="ORF">A0J61_03002</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the TRAFAC class dynamin-like GTPase superfamily. IRG family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000122">
        <property type="protein sequence ID" value="OBZ88946.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NKC1"/>
    <dbReference type="STRING" id="101091.A0A1C7NKC1"/>
    <dbReference type="InParanoid" id="A0A1C7NKC1"/>
    <dbReference type="OrthoDB" id="422720at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030385">
        <property type="entry name" value="G_IRG_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007743">
        <property type="entry name" value="Immunity-related_GTPase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051515">
        <property type="entry name" value="IRG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32341">
        <property type="entry name" value="INTERFERON-INDUCIBLE GTPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32341:SF10">
        <property type="entry name" value="INTERFERON-INDUCIBLE GTPASE 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05049">
        <property type="entry name" value="IIGP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51716">
        <property type="entry name" value="G_IRG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="33"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="70"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="domain" description="IRG-type G" evidence="6">
        <location>
            <begin position="123"/>
            <end position="306"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51716"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OBZ88946.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="356" mass="40061" checksum="338F8AE3BC0F5B48" modified="2016-11-30" version="1">MGQATSSPHSLSFFQRNSITNEYEDISNKFTKATVSTLAVPVIIIAYPVLNAYTFHDSDITGFRMIDGAIGGLLGVIGWPLAPFMAIWGAIRINFKDKPTLPLPVPTDILHQAQQQIHLNPTLFYNIAVVGSSGTGKSSVVNALRGYKDTHPEASRVGEVETTSKPKAFQHPDLTSMVIWDMPGVGTKSHPRETYFEDNFLCAFDLLVIVLGNRLMQDDINIALKAKDHRIPVLFVRSKADQAIDSKMKRYEENDTYQWATAVGELVVEVKDSVFTQLRQHQLNTKKLFIVSSHSLRLFVATINKKEARKSIQLIDEERFMTALIEGVMSKRRYFEKQAKLEEKRKKKKTSSLSSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NKI5</accession>
    <name>A0A1C7NKI5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 8">Chorismate synthase</fullName>
            <ecNumber evidence="4 8">4.2.3.5</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">A0J61_02306</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>5-O-(1-carboxyvinyl)-3-phosphoshikimate = chorismate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:21020"/>
            <dbReference type="ChEBI" id="CHEBI:29748"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57701"/>
            <dbReference type="EC" id="4.2.3.5"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>FMNH2</name>
            <dbReference type="ChEBI" id="CHEBI:57618"/>
        </cofactor>
        <text evidence="8">Reduced FMN (FMNH(2)).</text>
    </comment>
    <comment type="pathway">
        <text evidence="1 8">Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 7/7.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homotetramer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the chorismate synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.3.5" evidence="4 8"/>
    <dbReference type="EMBL" id="LUGH01000085">
        <property type="protein sequence ID" value="OBZ89642.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NKI5"/>
    <dbReference type="FunCoup" id="A0A1C7NKI5">
        <property type="interactions" value="288"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NKI5"/>
    <dbReference type="InParanoid" id="A0A1C7NKI5"/>
    <dbReference type="OrthoDB" id="1721239at2759"/>
    <dbReference type="UniPathway" id="UPA00053">
        <property type="reaction ID" value="UER00090"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004107">
        <property type="term" value="F:chorismate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042602">
        <property type="term" value="F:riboflavin reductase (NADPH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008652">
        <property type="term" value="P:amino acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009073">
        <property type="term" value="P:aromatic amino acid family biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009423">
        <property type="term" value="P:chorismate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd07304">
        <property type="entry name" value="Chorismate_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.150.10:FF:000004">
        <property type="entry name" value="Chorismate synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.150.10">
        <property type="entry name" value="Chorismate synthase AroC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00300">
        <property type="entry name" value="Chorismate_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000453">
        <property type="entry name" value="Chorismate_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035904">
        <property type="entry name" value="Chorismate_synth_AroC_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020541">
        <property type="entry name" value="Chorismate_synthase_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00033">
        <property type="entry name" value="aroC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003793">
        <property type="entry name" value="PRK05382.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21085">
        <property type="entry name" value="CHORISMATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21085:SF0">
        <property type="entry name" value="CHORISMATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01264">
        <property type="entry name" value="Chorismate_synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001456">
        <property type="entry name" value="Chorismate_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103263">
        <property type="entry name" value="Chorismate synthase, AroC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00787">
        <property type="entry name" value="CHORISMATE_SYNTHASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00788">
        <property type="entry name" value="CHORISMATE_SYNTHASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00789">
        <property type="entry name" value="CHORISMATE_SYNTHASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="6 8" id="KW-0057">Aromatic amino acid biosynthesis</keyword>
    <keyword evidence="7 8" id="KW-0456">Lyase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="35"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005044"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013036"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OBZ89642.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="397" mass="42555" checksum="29A6E8386FEC5951" modified="2016-11-30" version="1">MSSFGKIFRVTTYGESHCKGVGAIIDGCPPGMGLTEADIQPQLTRRRPGQSKLTTPRDEKDKVTIMSGTEFGVTLGTPIGIQVPNLDQRPHDYNDTDIFPRPSHADYTYLQKYSVKASSGGGRASARETIGRVAAGAIAEKYLREAYGVEIVAFASSVGKVAMPFVREFEDAESPKAELIKFMDTLTREDVDADISRCPDPQTAEGMKRVIAEKSEERDSVGGSVTCVIRKCPVGLGEPCFDKLEAVLAHAMLSIPATKGFEFGSGFSGTKMAGHQHNDPFVVKEDGSFGTITNNSGGIQGGISNGENIYFRVAFKPAATISQDQETANYDGVTGVLAAKGRHDPCVVSRAVPIVESMAALVIMDAVLQQEARRAAISRLPAIDINHSLLGKPPKKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NKV1</accession>
    <name>A0A1C7NKV1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Protein kes1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">kes1_1</name>
        <name evidence="4" type="ORF">A0J61_04013</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the OSBP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000187">
        <property type="protein sequence ID" value="OBZ87934.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NKV1"/>
    <dbReference type="STRING" id="101091.A0A1C7NKV1"/>
    <dbReference type="InParanoid" id="A0A1C7NKV1"/>
    <dbReference type="OrthoDB" id="14833at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008142">
        <property type="term" value="F:oxysterol binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.2720">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.160.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.3490">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037239">
        <property type="entry name" value="OSBP_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000648">
        <property type="entry name" value="Oxysterol-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018494">
        <property type="entry name" value="Oxysterol-bd_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10972:SF184">
        <property type="entry name" value="OXYSTEROL-BINDING PROTEIN HOMOLOG 4-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10972">
        <property type="entry name" value="OXYSTEROL-BINDING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01237">
        <property type="entry name" value="Oxysterol_BP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144000">
        <property type="entry name" value="Oxysterol-binding protein-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01013">
        <property type="entry name" value="OSBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="19"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003844"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OBZ87934.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="408" mass="46374" checksum="FF0E23A3C3EB3E61" modified="2016-11-30" version="1">MPLGFGSKKPHKTTEEDTPTSSDVDQLSMNNFDANEKGQFKEFKEFLKTVISFTGDLSSLTCPAFFLNGLSLLEYGTYWGDHPAAFTAISQAQAPEDRLLAISRWFMSTLYGSYASRCTDGKYEKKPYNPILGEKFFCKMGDATCVCEQVCHHPPISAFYLEDEKAGVSLNGHSGQKSKFKGTSIKVEQVGRAVLYLKQFDEQYMIDFPDLMIRGVLTGGSFIELSGVCTIIGSNNTKAVIEFVPKPWFGGEYNHIKGSLYADNKLQYTLSGRWSHESYYSRPNSEQKELLFDAKAEPMAERVTAPVEEQNEYETHRVWGPVTKALEEKNFKAANVEKTKIEDWQRKVRKEREEKKEAWSPSLFVFEKDVEAGNGYHQKNIDLKKSMDSKHHLDAGAWTYNKSLHLRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NMT7</accession>
    <name>A0A1C7NMT7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_03376</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000144">
        <property type="protein sequence ID" value="OBZ88574.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NMT7"/>
    <dbReference type="InParanoid" id="A0A1C7NMT7"/>
    <dbReference type="OrthoDB" id="2246723at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ88574.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="148" mass="17254" checksum="2B652AA5A91ED1EB" modified="2016-11-30" version="1">MSTLISAYDDLEGIEDEVSAEDWEIIFLCNKTTPAGLFQYFYFASEDKPLDGFLEQNKTTLNAFRDMKTSNKKALIDQMSLKMLENYERLTDNEKNILKLSLSYIVDLSGDSTNKCKKDMFDGLDFIHLEKSKLPRQRRHESNEYQIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NNE1</accession>
    <name>A0A1C7NNE1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Endoplasmic reticulum transmembrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">YET3_0</name>
        <name evidence="7" type="ORF">A0J61_01342</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">May play a role in anterograde transport of membrane proteins from the endoplasmic reticulum to the Golgi.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Endoplasmic reticulum membrane</location>
            <topology evidence="5">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the BCAP29/BCAP31 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000041">
        <property type="protein sequence ID" value="OBZ90607.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NNE1"/>
    <dbReference type="STRING" id="101091.A0A1C7NNE1"/>
    <dbReference type="InParanoid" id="A0A1C7NNE1"/>
    <dbReference type="OrthoDB" id="435607at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006888">
        <property type="term" value="P:endoplasmic reticulum to Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070973">
        <property type="term" value="P:protein localization to endoplasmic reticulum exit site"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008417">
        <property type="entry name" value="BAP29/BAP31"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040463">
        <property type="entry name" value="BAP29/BAP31_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12701">
        <property type="entry name" value="BCR-ASSOCIATED PROTEIN, BAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12701:SF20">
        <property type="entry name" value="ENDOPLASMIC RETICULUM TRANSMEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05529">
        <property type="entry name" value="Bap31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="5" id="KW-0931">ER-Golgi transport</keyword>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0653">Protein transport</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="100"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="domain" description="BAP29/BAP31 transmembrane" evidence="6">
        <location>
            <begin position="1"/>
            <end position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU367026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF05529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OBZ90607.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="176" mass="19985" checksum="1F904737578CA010" modified="2016-11-30" version="1">MTLYYSIVFGILAAELPVPTRWQKPVFRWLATSPFMAHAQYVMRIVFAFIFVLFLDAVNTLRAFYDVVSEEEGGIPPAGNADFRAQVGQAAKKFYAQRNLYLTGFTILLLLILGKIKAMSMDYIRLEDQYIELEGSVSKDPAVRKATKEIDTDPIDKKVTKLVPAEEPKKEDKKTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NNH1</accession>
    <name>A0A1C7NNH1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">40S ribosomal protein S28</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">RPS28A</name>
        <name evidence="4" type="ORF">A0J61_01950</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the eukaryotic ribosomal protein eS28 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000068">
        <property type="protein sequence ID" value="OBZ90016.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NNH1"/>
    <dbReference type="FunCoup" id="A0A1C7NNH1">
        <property type="interactions" value="412"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NNH1"/>
    <dbReference type="InParanoid" id="A0A1C7NNH1"/>
    <dbReference type="OrthoDB" id="6109at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022627">
        <property type="term" value="C:cytosolic small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030490">
        <property type="term" value="P:maturation of SSU-rRNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000028">
        <property type="term" value="P:ribosomal small subunit assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04457">
        <property type="entry name" value="S1_S28E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.140:FF:000025">
        <property type="entry name" value="40S ribosomal protein S28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00292">
        <property type="entry name" value="Ribosomal_eS28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000289">
        <property type="entry name" value="Ribosomal_eS28"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028626">
        <property type="entry name" value="Ribosomal_eS28_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10769">
        <property type="entry name" value="40S RIBOSOMAL PROTEIN S28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10769:SF3">
        <property type="entry name" value="SMALL RIBOSOMAL SUBUNIT PROTEIN ES28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01200">
        <property type="entry name" value="Ribosomal_S28e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00961">
        <property type="entry name" value="RIBOSOMAL_S28E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OBZ90016.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="67" mass="7625" checksum="AC0000366BD9C609" modified="2016-11-30" version="1">MDSKTPVKLARVTKVLGRTGSRGGVTQVRVEFMDDTNRSIIRNVKGPVRENDILCLLESEREARRLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NNK3</accession>
    <name>A0A1C7NNK3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Aquaporin PIP1-5</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">PIP1-5</name>
        <name evidence="10" type="ORF">A0J61_01361</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the MIP/aquaporin (TC 1.A.8) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000042">
        <property type="protein sequence ID" value="OBZ90588.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NNK3"/>
    <dbReference type="STRING" id="101091.A0A1C7NNK3"/>
    <dbReference type="InParanoid" id="A0A1C7NNK3"/>
    <dbReference type="OrthoDB" id="3222at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015250">
        <property type="term" value="F:water channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1080.10">
        <property type="entry name" value="Glycerol uptake facilitator protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023271">
        <property type="entry name" value="Aquaporin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034294">
        <property type="entry name" value="Aquaporin_transptr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000425">
        <property type="entry name" value="MIP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19139">
        <property type="entry name" value="AQUAPORIN TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19139:SF199">
        <property type="entry name" value="MIP17260P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00230">
        <property type="entry name" value="MIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00783">
        <property type="entry name" value="MINTRINSICP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81338">
        <property type="entry name" value="Aquaporin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="25"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="85"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="109"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="150"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="181"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="221"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="257"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="274"/>
            <end position="292"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OBZ90588.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="292" mass="31356" checksum="E4935619B5A28BB5" modified="2016-11-30" version="1">MRHIRDIYHYNKGPLPNFESDIKSAFGELVGMAIFIFLALSGVQTSLKAPAEAEAEGRLTLMQIQTIAISFGMGITVALFTTAHVSGGILNPAVLLSLVLIGDINWQRGLFFFLAEMIGGIIGAYFAYFITSGDFLGQNVLNPIYTDAQGVFAEALFTCALSLVVLFVIVDKRLMADYAPIVIGITVFLCHTLCTAIDGTSINPARSFAAAIVTGSWSKQWIFWVGPLTGAVFAVIIYLAAKVLTEDSMLESMLNPTTDQPKVGGIGTKEHASESGQSNHNPSVNIDIHSSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NNN9</accession>
    <name>A0A1C7NNN9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Recombining binding protein suppressor of hairless</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">RBPJ</name>
        <name evidence="10" type="ORF">A0J61_01226</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the Su(H) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000036">
        <property type="protein sequence ID" value="OBZ90725.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NNN9"/>
    <dbReference type="STRING" id="101091.A0A1C7NNN9"/>
    <dbReference type="InParanoid" id="A0A1C7NNN9"/>
    <dbReference type="OrthoDB" id="5600360at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001228">
        <property type="term" value="F:DNA-binding transcription activator activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.1450:FF:000003">
        <property type="entry name" value="Related to J kappa-recombination signal binding protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.80.10.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1450">
        <property type="entry name" value="LAG1, DNA binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015350">
        <property type="entry name" value="Beta-trefoil_DNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036358">
        <property type="entry name" value="BTD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040159">
        <property type="entry name" value="CLS_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008967">
        <property type="entry name" value="p53-like_TF_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015351">
        <property type="entry name" value="RBP-J/Cbf11/Cbf12_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037095">
        <property type="entry name" value="RBP-J/Cbf11_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038007">
        <property type="entry name" value="RBP-Jkappa_IPT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10665">
        <property type="entry name" value="RECOMBINING BINDING PROTEIN SUPPRESSOR OF HAIRLESS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09270">
        <property type="entry name" value="BTD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09271">
        <property type="entry name" value="LAG1-DNAbind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20144">
        <property type="entry name" value="TIG_SUH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01268">
        <property type="entry name" value="BTD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01267">
        <property type="entry name" value="LAG1_DNAbind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110217">
        <property type="entry name" value="DNA-binding protein LAG-1 (CSL)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="E set domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49417">
        <property type="entry name" value="p53-like transcription factors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="RBP-J/Cbf11/Cbf12 DNA binding" evidence="8">
        <location>
            <begin position="356"/>
            <end position="508"/>
        </location>
    </feature>
    <feature type="domain" description="Beta-trefoil DNA-binding" evidence="9">
        <location>
            <begin position="509"/>
            <end position="869"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="90"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="196"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="257"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="566"/>
            <end position="587"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="834"/>
            <end position="857"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="90"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="196"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="221"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="267"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="281"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="7">
        <location>
            <begin position="571"/>
            <end position="587"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="842"/>
            <end position="857"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009704"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM01267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM01268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OBZ90725.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="1013" mass="112511" checksum="14E60C476CAC914D" modified="2016-11-30" version="1">MATDNKKSHSECLEQNKNSWSDFVYSSPSSPHSQQQHQNEFHLDPTFTAQHMPESNSRRHSLSVGEMQLHSFDNQQHKYDLEQLLGASLPSSWSSSSSGTASTSHPHNTNNNNVDVIPHRRALSLRLDLGPTQPIDMHHRASFSTTSPTTPAFFSPSFLDALKQEDDMMFEQYHPHHSTPHPIPEEMVHDFMLNQQSQQHPQHNHHQQQQQHPLHHQHNNTSVAPTSNNTITPSIISTSDDVNHLTNYWLLNHQTPAPPAHIHRKSSTSSVSSINNTNHSPSQPTMNVVSTPSPPSTMTMVYQQQHPSIPEEEDEDMDTSLRNQSISARMLQGANNTAIMKPLIQRYLASSEDERRIMILTSRVAQKSYGTEKRFLCPPPSTILLGASWHTMANDGLSSKPSPPSLVIQISGEKTSQNGMVEWQYDGNNMESHRDIPLLSSTNNTSGVIGYCVSKHLHINDADEKRKRVEVLVKISLANNVLLGTFASKGIKVISKPSKKRQSVKNMELCIHHGTTISLFNRIRSQTVSTKYLGVSSGADNPTGTCFVARTSSWDPFVIWVVDTTRSPESQPQPLPHHPDNPHFPAPPTIAMQTSPGQTPIAIHYNQAIVLQCVTTGLVSPVMVIRKVDKGSMTMGGNRVDDLSGPTGGECGDEALGDPVSQLHKVAFQIVQDPSVAHHNKVNYNSSTLPSQHPHLMQEWQLPQLSQTVTYLACLDNVVGMHKTTTERTFVLTHPAVPPPVDSSALLSSSWSTADSFENFEFMSSVQQQQQQQANINTAATINNHANGGGGKMTRKRRVSCDVTGKPLMPPILKNNSSNRRRVNSLNDNLFYKQEQVGGAGRRSSISSDRRSSIGSDHGYHQLNSGACWTEDVSDASVWTIVGTDCASYKFWAPSTIGDLNSPFTSNTANPITPFPMLNTSYTHLVHSKQPQQQHTLHLHGQNFTRDISVWFGDVKSPHTDYKSKDSISCTVPNIQEMMDSSSAIHEDLQHKIPILFVRGDGIIYNTDMFYTF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NNY0</accession>
    <name>A0A1C7NNY0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">HECT-type E3 ubiquitin transferase</fullName>
            <ecNumber evidence="3">2.3.2.26</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">mug30</name>
        <name evidence="9" type="ORF">A0J61_01371</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.</text>
            <dbReference type="EC" id="2.3.2.26"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.26" evidence="3"/>
    <dbReference type="EMBL" id="LUGH01000042">
        <property type="protein sequence ID" value="OBZ90589.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NNY0"/>
    <dbReference type="FunCoup" id="A0A1C7NNY0">
        <property type="interactions" value="74"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NNY0"/>
    <dbReference type="InParanoid" id="A0A1C7NNY0"/>
    <dbReference type="OrthoDB" id="8068875at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000209">
        <property type="term" value="P:protein polyubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00078">
        <property type="entry name" value="HECTc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.2160.10:FF:000004">
        <property type="entry name" value="probable E3 ubiquitin-protein ligase HERC4 isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.2410.10:FF:000003">
        <property type="entry name" value="probable E3 ubiquitin-protein ligase HERC4 isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2160.10">
        <property type="entry name" value="Hect, E3 ligase catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2410.10">
        <property type="entry name" value="Hect, E3 ligase catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1750.10">
        <property type="entry name" value="Hect, E3 ligase catalytic domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044611">
        <property type="entry name" value="E3A/B/C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000569">
        <property type="entry name" value="HECT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035983">
        <property type="entry name" value="Hect_E3_ubiquitin_ligase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45700:SF8">
        <property type="entry name" value="HECT-TYPE E3 UBIQUITIN TRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45700">
        <property type="entry name" value="UBIQUITIN-PROTEIN LIGASE E3C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00632">
        <property type="entry name" value="HECT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00119">
        <property type="entry name" value="HECTc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56204">
        <property type="entry name" value="Hect, E3 ligase catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50237">
        <property type="entry name" value="HECT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="6 7" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="HECT" evidence="8">
        <location>
            <begin position="302"/>
            <end position="629"/>
        </location>
    </feature>
    <feature type="active site" description="Glycyl thioester intermediate" evidence="7">
        <location>
            <position position="597"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OBZ90589.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="629" mass="72627" checksum="802993F20784A573" modified="2016-11-30" version="1" fragment="single">TVQSCKSKEKKKASDELDREKIYEPVEKLMEINFGNWICLNNSFLNGKSTTLEESGIDLQDIKIAYRIILSSPVNVIRAMMSAIERLLKRPGMPLRKITDIRFLLIILENPLLIQHNFPAETKYHHNLLKRIFGIISCLGNECHHALVNWFSSYPIKKFRLKMDLVHVFLSHRISKARRSRLSLPAAYESDWKIIIAANNQANKVSISEFYNTMADYIDLMGDFELWQSRSGKFAFCQYPFLISMGSKMKIVESDAKQQMETKWREAFFNMIFHQKISNPYLVLRVSRDNLIEDSLRQLAQNEVDLKKSLRIEFVGEDGVDAGGLRKEWFLLLVRSLFDPQYGMFTYDEDLNLCWFNPASFENEDQFFLVGIVLGLAIYNSTILDVHLPTACYKKLLNLPVGLHDLKSFRPSLAKGLEQLLTFEGDVEEVFCRSFVAELEVFGQRHCVPLIPHGDRIPVNQHNRKEFVSLYTDFLLNKSVERQFGAFKRGFYYVCGGNALSLFQPEEIELLVRGSDEPLAIDDIRGQTEYIGFDKHEETIVNFWNIMNNMKPAIQRKLLMFVTGSDRIPATGATQLRLKIVCGNNGDSDRLPSAHTCFNQLTLYKYHTKEKLEKMLLTAIQESQGFYFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NPB7</accession>
    <name>A0A1C7NPB7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">30S ribosomal protein S7</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">rpsG</name>
        <name evidence="6" type="ORF">A0J61_00981</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the universal ribosomal protein uS7 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000026">
        <property type="protein sequence ID" value="OBZ90971.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NPB7"/>
    <dbReference type="FunCoup" id="A0A1C7NPB7">
        <property type="interactions" value="229"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NPB7"/>
    <dbReference type="InParanoid" id="A0A1C7NPB7"/>
    <dbReference type="OrthoDB" id="9972728at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.455.10">
        <property type="entry name" value="Ribosomal protein S7 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000235">
        <property type="entry name" value="Ribosomal_uS7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020606">
        <property type="entry name" value="Ribosomal_uS7_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023798">
        <property type="entry name" value="Ribosomal_uS7_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036823">
        <property type="entry name" value="Ribosomal_uS7_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11205">
        <property type="entry name" value="RIBOSOMAL PROTEIN S7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00177">
        <property type="entry name" value="Ribosomal_S7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47973">
        <property type="entry name" value="Ribosomal protein S7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00052">
        <property type="entry name" value="RIBOSOMAL_S7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 6" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Small ribosomal subunit protein uS7" evidence="5">
        <location>
            <begin position="29"/>
            <end position="166"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003619"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OBZ90971.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="177" mass="19950" checksum="08B10654D89FBC07" modified="2016-11-30" version="1">MSILLQTLRQQGTFLNNLQSSVRTLTTHVTAVPNNEVVSQLVNTLMRDGKKARAQRLISDSMKQLSKKITPETDPYNVLYEAIESASPLLKLSSTKKGSKVVHVPTALRDRQRRRRAIVWMLDASKKRGEKSFEERFAAEVFDVSQGTSTVLQKKAQVHKQALANRANAQVSYNTQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NPE0</accession>
    <name>A0A1C7NPE0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Ribosomal RNA-processing protein 7 A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">Rrp7a</name>
        <name evidence="6" type="ORF">A0J61_01648</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the RRP7 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000055">
        <property type="protein sequence ID" value="OBZ90306.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NPE0"/>
    <dbReference type="STRING" id="101091.A0A1C7NPE0"/>
    <dbReference type="InParanoid" id="A0A1C7NPE0"/>
    <dbReference type="OrthoDB" id="5390at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032545">
        <property type="term" value="C:CURI complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034456">
        <property type="term" value="C:UTP-C complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000028">
        <property type="term" value="P:ribosomal small subunit assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd12293">
        <property type="entry name" value="dRRM_Rrp7p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd12951">
        <property type="entry name" value="RRP7_Rrp7A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.1770">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040447">
        <property type="entry name" value="RRM_Rrp7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040446">
        <property type="entry name" value="RRP7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024326">
        <property type="entry name" value="RRP7_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13191">
        <property type="entry name" value="RIBOSOMAL RNA PROCESSING PROTEIN 7-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13191:SF0">
        <property type="entry name" value="RIBOSOMAL RNA-PROCESSING PROTEIN 7 HOMOLOG A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17799">
        <property type="entry name" value="RRM_Rrp7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12923">
        <property type="entry name" value="RRP7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rrp7 RRM-like N-terminal" evidence="5">
        <location>
            <begin position="23"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="domain" description="Ribosomal RNA-processing protein 7 C-terminal" evidence="4">
        <location>
            <begin position="202"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="114"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="290"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="130"/>
            <end position="144"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF12923"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF17799"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OBZ90306.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="323" mass="37801" checksum="EB13AD779AA0405B" modified="2016-11-30" version="1">MAKSKKVETVEQSAKQSKQLQEFQGFKILPVIVTEDKSARHYFYMRKHESKSLIDENIRDRTLFLLNLPADTTDRHIKKLFKGHAIDQITYSDSGSSVTEEYWKIMEANQAAAAAAEASEKSKKNSKKRKSEENDEEKKEAVHQRELRRLFTSGSSAHVVFSTDQDLVDVLNMHRVEKKWAKEDEDSEQPLGLGRYLLTYQLSRPNAHDLQKEVDSFMMKFKEDEYKKERETLERMNQMDEDGFTVVVRHKKAKTTDGSINVASISADAADAYKPKKKKELVNFYRFQMREQKQNELSELRKRFEEDKVKIAKLKQSRKFKPY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NPK2</accession>
    <name>A0A1C7NPK2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Receptor y region, transmembrane domain-and RING domain-containing protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">RMR1_3</name>
        <name evidence="11" type="ORF">A0J61_01584</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000052">
        <property type="protein sequence ID" value="OBZ90356.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NPK2"/>
    <dbReference type="STRING" id="101091.A0A1C7NPK2"/>
    <dbReference type="InParanoid" id="A0A1C7NPK2"/>
    <dbReference type="OrthoDB" id="8062037at2759"/>
    <dbReference type="UniPathway" id="UPA00143"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016567">
        <property type="term" value="P:protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006511">
        <property type="term" value="P:ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd16454">
        <property type="entry name" value="RING-H2_PA-TM-RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003137">
        <property type="entry name" value="PA_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051834">
        <property type="entry name" value="RING_finger_E3_ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45931:SF3">
        <property type="entry name" value="RING ZINC FINGER-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45931">
        <property type="entry name" value="SI:CH211-59O9.10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02225">
        <property type="entry name" value="PA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13639">
        <property type="entry name" value="zf-RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-0675">Receptor</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 9 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 8" id="KW-0863">Zinc-finger</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="7"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="229"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="domain" description="RING-type" evidence="10">
        <location>
            <begin position="325"/>
            <end position="366"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="OBZ90356.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="410" mass="47267" checksum="189A7E31609F1CF2" modified="2016-11-30" version="1">MIRCRPTITYPLGIILIIWVLLGAIVFPNANHWLKGTSSSIEQDTMSFDLNRPIQNRNALFETSEHKSYRDHVFSMLNAPSVSLYGTRGVLYHQRDACQHSNESYSVPTVLNQPSFSELAKIALIENNQACRLTDKIILAQNNGAAATIVFSPNYEEDLSNISSHLSFSEQDVTSNQVQIPSYFVDLNIGMSLLRDVYRLHRQEPRQGYSQFVVRVRLVAGRPPDLDHWQFGLVIVGIMLFSCVVAMTILHCHLWHIRRSRQQINSSQEVLTLEEQQLMNETNQQLWRYLNTPTKQRTRHRLDQHVVDMLPLRTFKTKDPNHQGCVICLDGFEKGQELRQLPCSHEYHRDCIDKWLTKKNNTCPLCLHRIELPAVPEQAYTTSTTPDLADTWHHLEQSALNQHYSKSSRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NQ41</accession>
    <name>A0A1C7NQ41_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Global transcription regulator sge1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">sge1_1</name>
        <name evidence="2" type="ORF">A0J61_02571</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000098">
        <property type="protein sequence ID" value="OBZ89374.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NQ41"/>
    <dbReference type="InParanoid" id="A0A1C7NQ41"/>
    <dbReference type="OrthoDB" id="5572844at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018608">
        <property type="entry name" value="Gti1/Pac2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28027">
        <property type="entry name" value="TRANSCRIPTIONAL REGULATOR MIT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28027:SF2">
        <property type="entry name" value="TRANSCRIPTIONAL REGULATOR MIT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09729">
        <property type="entry name" value="Gti1_Pac2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="89"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="204"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="311"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="499"/>
            <end position="556"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="92"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="108"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="207"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="313"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="358"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="499"/>
            <end position="528"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ89374.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="615" mass="68330" checksum="059115CD774F1C7E" modified="2016-11-30" version="1">MAETFHGYVETTQDVLLIFEGCRRGLIPRVHRRLQEKERRMIRSGSIFVFDERESGIKRWTDGLVWSPSRILGNFLIYRELDKRAPGEKKLSISSASSNDSRQRSYSADQTAINTTPTDRNRERRLVGSLSDSYRFRKDGLIKKTMSIIVNGVAQHLISYYLPNDIINNQLRTPSSVPELASLEISPDLLVKQNFRIPPMVEPPFDQSETSMPGNLNNSISPVESMSSSYVTDRRIHPFRSMSMGSLRNPNSYQTHNNLSTMGRPEMNTNQQNLMYSATSSFPQRVEVDDNPNKLPGNSFAYYGNQAMPSIYNGSNSNNNNGSNNNSNNNSGNSNNSNNTSSNNNGTSNNGFPPLPSPSSMTSSPNTPMLSPVRQSFCQTRPYPMSSTSSSSLPRFNTHRDSFDMASSNIEGRPSPSVHPHMVSEVNIYGGDHRMKADNIEMGDSANTSSPHIGQLLNPVHPLSANVMKATGEDNTSSQQLFQTMGMANAAPTYPSYSADNVPATSTSTHNRLSFDSSKLPSIPSETNSLHHEPTTQPPPQSQPQQQDPSFNTYGGNYYFQRQQIHHPLNNTHSSTSTSTIHPMFRNGMVYPQLSSMNDESQISSESGTEPLMLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NQ58</accession>
    <name>A0A1C7NQ58_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Protein stu-1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">stu-1</name>
        <name evidence="8" type="ORF">A0J61_00694</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
            <location evidence="1">Spindle</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the CLASP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000017">
        <property type="protein sequence ID" value="OBZ91252.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NQ58"/>
    <dbReference type="STRING" id="101091.A0A1C7NQ58"/>
    <dbReference type="InParanoid" id="A0A1C7NQ58"/>
    <dbReference type="OrthoDB" id="46159at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005881">
        <property type="term" value="C:cytoplasmic microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005815">
        <property type="term" value="C:microtubule organizing center"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072686">
        <property type="term" value="C:mitotic spindle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005876">
        <property type="term" value="C:spindle microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008017">
        <property type="term" value="F:microtubule binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090307">
        <property type="term" value="P:mitotic spindle assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024395">
        <property type="entry name" value="CLASP_N_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21567">
        <property type="entry name" value="CLASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21567:SF9">
        <property type="entry name" value="CLIP-ASSOCIATING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12348">
        <property type="entry name" value="CLASP_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="3" id="KW-0132">Cell division</keyword>
    <keyword evidence="4" id="KW-0493">Microtubule</keyword>
    <keyword evidence="5" id="KW-0498">Mitosis</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CLASP N-terminal" evidence="7">
        <location>
            <begin position="20"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="247"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="416"/>
            <end position="514"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="263"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="297"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="416"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="437"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="460"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="6">
        <location>
            <begin position="486"/>
            <end position="496"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009549"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF12348"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OBZ91252.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="554" mass="62118" checksum="783822AC69A36476" modified="2016-11-30" version="1">MIIDIYPKNTIKITTKTEYEREMKRIIELFTQKETEETWEQFKRALNNLSLWIAEDKVSTFPTFEHHIKKLKLPIIRCLESPRTLLSASASGLLKTMAQNMETKFAAKLNPLFIQAVIKQFGSTNKVHTARVLTDYKQVIEYAKLPKCIPQFSDYLTDKTKHKNNSNLRCCLAECLLVLIQVNPEVILKRFSNEIEKAIRIASTDASASVRSVIRDLYKTYREKMPELFAIFHLTLTTTERKHLEAKSTPVAISRSASSSGSLHRTTTKSSAVLPRKSSSAQLGHKRTIDPKKGTPTRHSLPTLTRSSITTQLPAEPSQAVATKTTYEENDTTTSTQTNTPLVDLSTHSINNHLNQPMTHTPIDTQELNSPNTIKDSQETTLTAFSSMTASTEHTIIHTTEPESLPIEANDLILSSSSSSSSFSLPSPSSSSISVTENKRQHEDDTHTIRSAKKQKTLPPISTTKRTKSSLPPRTLSKSTEESQALPPPPPPPPSSSLPSSDEHHEVIGGSNVLQRFSNRRFVAKPFFPKKEAVPKLQFKKKGFGPNFRYKKRM</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NQD2</accession>
    <name>A0A1C7NQD2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Transcriptional activator SPT7</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">SPT7</name>
        <name evidence="10" type="ORF">A0J61_01284</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000039">
        <property type="protein sequence ID" value="OBZ90646.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NQD2"/>
    <dbReference type="FunCoup" id="A0A1C7NQD2">
        <property type="interactions" value="23"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NQD2"/>
    <dbReference type="InParanoid" id="A0A1C7NQD2"/>
    <dbReference type="OrthoDB" id="21449at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000124">
        <property type="term" value="C:SAGA complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046695">
        <property type="term" value="C:SLIK (SAGA-like) complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046982">
        <property type="term" value="F:protein heterodimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005198">
        <property type="term" value="F:structural molecule activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006325">
        <property type="term" value="P:chromatin organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd22927">
        <property type="entry name" value="HFD_SPT7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.920.10">
        <property type="entry name" value="Bromodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.20.10">
        <property type="entry name" value="Histone, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001487">
        <property type="entry name" value="Bromodomain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036427">
        <property type="entry name" value="Bromodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018359">
        <property type="entry name" value="Bromodomain_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006565">
        <property type="entry name" value="BTP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009072">
        <property type="entry name" value="Histone-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037782">
        <property type="entry name" value="Spt7"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47343">
        <property type="entry name" value="TRANSCRIPTIONAL ACTIVATOR SPT7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47343:SF1">
        <property type="entry name" value="TRANSCRIPTIONAL ACTIVATOR SPT7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07524">
        <property type="entry name" value="Bromo_TP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00439">
        <property type="entry name" value="Bromodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00503">
        <property type="entry name" value="BROMODOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00297">
        <property type="entry name" value="BROMO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47370">
        <property type="entry name" value="Bromodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00633">
        <property type="entry name" value="BROMODOMAIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50014">
        <property type="entry name" value="BROMODOMAIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 6" id="KW-0103">Bromodomain</keyword>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Bromo" evidence="9">
        <location>
            <begin position="296"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="385"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="995"/>
            <end position="1119"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="198"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="396"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="414"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="445"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="491"/>
            <end position="507"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="1036"/>
            <end position="1088"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="1089"/>
            <end position="1099"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="1100"/>
            <end position="1112"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OBZ90646.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="1119" mass="129251" checksum="468518679FCF64EB" modified="2016-11-30" version="1">MLTHKNLPPWLLLSYILSQHLVQKEYHKRYLNAIEQTYFLDALVSLATWIAFITLEGKGELNTTAFRVRSMLYEQMIPHLFQHKACCKHIDLTSIAEQARLLHLPDPSEITSALEQYKEAHVKKEEEPEPIQTTVTEEGEEEANVVTTSDIPGKLVKKVMIDGFMSATTNNREEIQANDQVPLMDVFHTLELDMAAMIEQRKLEEFEAQEELNEAEEARENAAKSLQMFNADGNFNLKYLLQGIVANRQKTSLSDRELQNLLSDFKPHRSKWSNDDRVGQEELYEACEKVLTDLKNYTEHSTPFLNKVNKREAPDYFDVIEKPMDLGTVTKKMKNLAYRSKKEFADDLYLIYENCLAYNTTTGNEYRKHAIAMRRKTERLLSRVPNISIKETRPENEEEVDFSEEEEEPSSVHQSRKSTGKHRLSTHERTATPVLDRQSRERSMTRGSSVMDHQSDIESTPEPNNHRYYGGKHVQKNQSGYSNLEEQQQQQEEEEEEEESKLDDGEFGDQVWREKTKKTRARLTTDVEKQYQFPFSEREALVRSSMDMERFTMMEHLHDHPESVMRLMRVDADRFLQWTDRRSHQASLLDEFDLDSSDDENLDAFFSRKMTKPDKTVDDAVKTDLFLPSYAITSGLPEIDGLPEDLVEPVVGDQMVRRKSSVDLSPETLLASQGYSSLSFDLFPELDFPDYGLNPLIDKSNAKLDQIRRIYAKCNAVRNNMPLSLLKDTNDRSLVPAKTAYTTKPLLAMNSESGHQMAQKILSKLLLHAGFEGAKTGALNVLTDIMIDFLVSIGKTMRSYWDDYGHQMHGDVSQGIVYTRWLYSSTELQKEMVSHSLYENGILDISELEEYVHDDIERGMQRLDDLHRRLQTSYQDLLSGPIEKSIENEEELLNEEETFITGIFGEDLGEDYFGFKNIGLDQEYSINALQIPSHLWFGKSKDKAPIKSMAAKEPSFRFTPPPSFVPVTSEKAFVGLLQPYFAQKLPLIEDEFIPNRNKNRPRYPPTNKVAANRKKLGKDLHLGAGADHKKYKRKRPAEEIVAEKAEKAEKKRLKMEEKAQRIAEKEQKRRMREELREQEKQARIEAKEKKKLLNKKTKQPKNNANTQSVDSSSVKDEED</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NR85</accession>
    <name>A0A1C7NR85_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">40S ribosomal protein S27</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">rps27_1</name>
        <name evidence="6" type="ORF">A0J61_01007</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="5">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the eukaryotic ribosomal protein eS27 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000027">
        <property type="protein sequence ID" value="OBZ90936.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NR85"/>
    <dbReference type="FunCoup" id="A0A1C7NR85">
        <property type="interactions" value="363"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NR85"/>
    <dbReference type="InParanoid" id="A0A1C7NR85"/>
    <dbReference type="OrthoDB" id="5567124at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="2.20.25.100:FF:000001">
        <property type="entry name" value="40S ribosomal protein S27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.25.100">
        <property type="entry name" value="Zn-binding ribosomal proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00371">
        <property type="entry name" value="Ribosomal_eS27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000592">
        <property type="entry name" value="Ribosomal_eS27"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023407">
        <property type="entry name" value="Ribosomal_eS27_Zn-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011332">
        <property type="entry name" value="Ribosomal_zn-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11594">
        <property type="entry name" value="40S RIBOSOMAL PROTEIN S27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01667">
        <property type="entry name" value="Ribosomal_S27e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57829">
        <property type="entry name" value="Zn-binding ribosomal proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01168">
        <property type="entry name" value="RIBOSOMAL_S27E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 5 6" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="2 5" id="KW-0862">Zinc</keyword>
    <keyword evidence="5" id="KW-0863">Zinc-finger</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU000671"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OBZ90936.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="84" mass="9239" checksum="0291C56892AF7676" modified="2016-11-30" version="1">MTLAIDLLNPSVEHEKRSHKLKRLVQSPNSYFMDVKCPGCLNISTVFSHAQTVVLCSSCGTVLCQPTGGRARLTEGCSFRRKAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NRB3</accession>
    <name>A0A1C7NRB3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">SAP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_00302</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000006">
        <property type="protein sequence ID" value="OBZ91642.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NRB3"/>
    <dbReference type="InParanoid" id="A0A1C7NRB3"/>
    <dbReference type="OrthoDB" id="445357at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.720.30">
        <property type="entry name" value="SAP domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003034">
        <property type="entry name" value="SAP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036361">
        <property type="entry name" value="SAP_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02037">
        <property type="entry name" value="SAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00513">
        <property type="entry name" value="SAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF68906">
        <property type="entry name" value="SAP domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50800">
        <property type="entry name" value="SAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SAP" evidence="2">
        <location>
            <begin position="361"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="129"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="286"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="397"/>
            <end position="541"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="8"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="18"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="142"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="159"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="183"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="249"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="286"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="302"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="421"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="446"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="486"/>
            <end position="520"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50800"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ91642.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="684" mass="76750" checksum="14F77B442EC3E78C" modified="2016-11-30" version="1">MYHYNHHIHSESEDSRHYSNSNSDNTSPLFHHGVDPVNLDELPSQFLNNDPSTMLNDSLFDFNSSQWDFLLNTHQQDDTYQQETILLSDPNFLRQHQLLQDQQRDMQIRMQDDSKEQVSNLTAMLDTTAIVKPTKQKRNSTGRRQQTLSKSTSDTNTDDASKIDHQRRFNELQARFRVNYARKPTNNSSNSSSKLTPKPKSINKPKSPNPSFVNNPPPPPLSPTTIDVPPVITAPPAPVNTHNNTSLHLPPPPPPPCSSPTPPPLSLAQHDTPKPKLEFTLTHPALSPSLLHSPTTLSTHEPLVDTERNRPEDSEDRLSSSFPSRTMPIQIQRMSRPNQNQPFDAESHQRLLDSQLDKVDFDDITVSELKEMLRQRGKPATGKKAVLLXRLQEERDLAKGGGGKSPNRMNFRHSQPLPFSRSINSSEHSGNSRPRSFQGSSPVAIQQNYHQQQHQQDTLAASPNLLPPSSPGGQLHRSIANMHIGSPPTASRRYSPYSPRLSSSPKPSCSFYSSSVPLSSGEVTSPGHPSRPVQPQTEEANGGMMLSSSYSIANNKPPTTPGRYYNNPKTYKPFTSSALATPDREEDINPFDRYYANQDAPVIKEEEIDNNDMDWSDPVALDMLLQQGTINMNTAQMLGQPLYSDDVVLTNEQIMSLINSQQQATPFEFKIEENSHFNTHYHPH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NRQ0</accession>
    <name>A0A1C7NRQ0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_00848</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000022">
        <property type="protein sequence ID" value="OBZ91096.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NRQ0"/>
    <dbReference type="InParanoid" id="A0A1C7NRQ0"/>
    <dbReference type="OrthoDB" id="419631at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.1490">
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="353"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="42"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="109"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="363"/>
            <end position="385"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ91096.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="397" mass="45908" checksum="863F17B9E2ED898E" modified="2016-11-30" version="1">MDLVVQSLEAEKKDTKAILIAKDLELAELRSKNGILQKTINRQEVANKTSQLQKKIDQLQNTLQSSQSSYKETLAEKNAAIATMHSELQECATKIDQLKLAQQIGQQRHESLEAQIATLSAHLSESQADATQKQMQLKQLQHDILSSNETNRALVEKLEASQQQIIDLESQRQQLTEDIKAQQDHVNQLESRLEIQENKMKDALRTVEQKNALVEEKTNLIEKLIEQFKTYRTWMHGDVIPRLRQERDKEKQKHVDELNRALSELHEAKKFVNKQALHLDELKSDVYWLTKQNKQLHTLVQHMHDEHKEHVQFNMRLFSGTLDQLTPMTTVLPKNKQNRPKATHRKRVVFKKKNRQETEDSDTSISFTSHSSLSDALQDSDSFNNDSGFDVLADEMK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NRQ3</accession>
    <name>A0A1C7NRQ3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">intramembrane prenyl-peptidase Rce1</fullName>
            <ecNumber evidence="10">3.4.26.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">Sras</name>
        <name evidence="13" type="ORF">A0J61_00228</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>Hydrolyzes the peptide bond -P2-(S-farnesyl or geranylgeranyl)C-P1'-P2'-P3'-COOH where P1' and P2' are amino acids with aliphatic sidechains and P3' is any C-terminal residue.</text>
            <dbReference type="EC" id="3.4.26.1"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peptidase U48 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.26.1" evidence="10"/>
    <dbReference type="EMBL" id="LUGH01000004">
        <property type="protein sequence ID" value="OBZ91763.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NRQ3"/>
    <dbReference type="FunCoup" id="A0A1C7NRQ3">
        <property type="interactions" value="347"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NRQ3"/>
    <dbReference type="InParanoid" id="A0A1C7NRQ3"/>
    <dbReference type="OrthoDB" id="271604at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071586">
        <property type="term" value="P:CAAX-box protein processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039731">
        <property type="entry name" value="Rce1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003675">
        <property type="entry name" value="Rce1/LyrA-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13046:SF0">
        <property type="entry name" value="CAAX PRENYL PROTEASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13046">
        <property type="entry name" value="PROTEASE U48 CAAX PRENYL PROTEASE RCE1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02517">
        <property type="entry name" value="Rce1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 13" id="KW-0645">Protease</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="37"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="77"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="187"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="245"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="domain" description="CAAX prenyl protease 2/Lysostaphin resistance protein A-like" evidence="12">
        <location>
            <begin position="122"/>
            <end position="228"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006897"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00047280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00049729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF02517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="OBZ91763.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="278" mass="32028" checksum="BA0B978AD296DB92" modified="2016-11-30" version="1">MTTVAHLVCLSFTFIYVAGFYVFSVQGDRNSPNVIRARMKSVMLASLLSALMVWYYLQATTDYLWVALGIRPVSWYLLSPLFLTVLLFLGPLSVLYFDRELPFQTHCSFSDIKAIWTSLIGQRNYCVGPLTEEFVFRACMIAVLFHAGMNSSQLIFISPLYFGVAHVHHAWNTYVQLGKTHQALKRALFSSLFQFVYTSIFGWYESYLFLRLGSLWPPVLCHSFCNMMGFPDLDGFSYRPKYQKYIIASCFISGLVLFIYYFSRLTHPDLVGGSMYWP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NRV6</accession>
    <name>A0A1C7NRV6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_00082</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000002">
        <property type="protein sequence ID" value="OBZ91847.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NRV6"/>
    <dbReference type="STRING" id="101091.A0A1C7NRV6"/>
    <dbReference type="InParanoid" id="A0A1C7NRV6"/>
    <dbReference type="OrthoDB" id="8249012at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ91847.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="106" mass="12123" checksum="35045ECE9E82AF0C" modified="2016-11-30" version="1">MPSHSFFLFCSLTLLRNSVKLKDDISLVFSALDRQEYALDPTLLSLKRQPVDPRVVQKAYDRLFATVQTIDERTIPQVTIKELNENHDQFTSSITNAIHLCGFVVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NRV9</accession>
    <name>A0A1C7NRV9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_00253</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000005">
        <property type="protein sequence ID" value="OBZ91700.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NRV9"/>
    <dbReference type="InParanoid" id="A0A1C7NRV9"/>
    <dbReference type="OrthoDB" id="2285800at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="112"/>
            <end position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ91700.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="177" mass="20255" checksum="CCB1DD478ED2CC3A" modified="2016-11-30" version="1">MSFNDSIQDTIPGFQIMCLTPEEDDYPYEDQYDDQQDICWLDDCECQENLATILPLIPEACIVDKDNHIQSMDGIHVFFEELGYFTEEPEPIDPTRDYDAEAKQLLEERNKTRKQHIDLSPVPSLDNTDSGMSSTSSSFHAIDEQHPTVHIRSPLSQTHNKSVSTHTTYIPLLHNLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NRY8</accession>
    <name>A0A1C7NRY8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">SMP-LTD domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">A0J61_00258</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000005">
        <property type="protein sequence ID" value="OBZ91699.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NRY8"/>
    <dbReference type="FunCoup" id="A0A1C7NRY8">
        <property type="interactions" value="29"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NRY8"/>
    <dbReference type="InParanoid" id="A0A1C7NRY8"/>
    <dbReference type="OrthoDB" id="26740at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032865">
        <property type="term" value="C:ERMES complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008289">
        <property type="term" value="F:lipid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990456">
        <property type="term" value="P:mitochondrion-endoplasmic reticulum membrane tethering"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015914">
        <property type="term" value="P:phospholipid transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd21675">
        <property type="entry name" value="SMP_TEX2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058801">
        <property type="entry name" value="PDZD8_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031468">
        <property type="entry name" value="SMP_LBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13466:SF19">
        <property type="entry name" value="NUCLEUS-VACUOLE JUNCTION PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13466">
        <property type="entry name" value="TEX2 PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26547">
        <property type="entry name" value="PDZD8_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51847">
        <property type="entry name" value="SMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="6" id="KW-0445">Lipid transport</keyword>
    <keyword evidence="7" id="KW-0446">Lipid-binding</keyword>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="7"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="domain" description="SMP-LTD" evidence="11">
        <location>
            <begin position="245"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="458"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="526"/>
            <end position="864"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="469"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="552"/>
            <end position="573"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="575"/>
            <end position="588"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="589"/>
            <end position="598"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="616"/>
            <end position="640"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="643"/>
            <end position="652"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="656"/>
            <end position="667"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="690"/>
            <end position="703"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="704"/>
            <end position="713"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="742"/>
            <end position="758"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="9">
        <location>
            <begin position="787"/>
            <end position="800"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="808"/>
            <end position="830"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="9">
        <location>
            <begin position="835"/>
            <end position="844"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004586"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="OBZ91699.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="864" mass="97683" checksum="058DB616F0947DB5" modified="2016-11-30" version="1">MSLLGFLCVYILGGVTFLPIVVIVAFLFVKKNSQPFKPESKSTIEPLLVDEHDEPVLKKGWIRLINQYHPKMPEASSNSSIMSYVGGGNQSLKKGVAYAVLERDTLYCYESEKQQERIMMLSLNEYEVSLYPDTASRTEGELFNRSTMIRMVPKNLKNDINLTSKTPSEMSNTDEETTCNPAKTLYLTCARNTDKEDWYFGLLRAKKYQLSDTNEAHEDCIWMDNTHFDPPALEKLIHQVRSTPGQRETAWLNAIIGRLFLSIYKTDRLKEFVDMKIRQKINKTKRPTFLDEIHVRNVDVGQSVPSITNPKLLSLTPEGEVVVEAQVDYSGGLTIEIETDFNWSYSSRMKPIRMHLVLAVKLKKLAGRLMFKIKAPPTNRYWVSFFEMPEMEWNITPVVADKQIKLNIVTNAIESRIREVMAETFVLPNMDDTPFYQSEGKGGIFGSYVKVPVKKTTSYKHKPERKDSTVSTTSSSSSSSNASHGSNKVFVSPDQLKEAPTVPELHEKSPASDVLKLKSRRAESVTGLALDQQSSMQKLEGSRSAPDMQPILKEENLLEDKEEIDKEIRKPDSFSEGSIDQRSITETGSSTSKWSSSSLYIRKRIKKPEEDHSDTESINSFRSNQSNNGSKFFNKINQFLPSADREHQDSARQVHAAQSSPNSSSMLMNKKNAIVSAVGQYLSKKMQNNDSEDESPKDEDETASESKRERYAERLANMQKRAKERSQSSSSFNLSDSDRADQSFSTPSTNQSHTSPIISSEKPGRYRAASTVQRPTDIVNEDRSNKPPLPPRRYSTPPPMSQEVTIEAAKDAIKPPIFKEEKEFHQHQQEQEQPTSPPPLPTSPRPLSKPDAADQNIPPLPPRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7LJS8</accession>
    <name>A0A1C7LJS8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">glucosamine-6-phosphate deaminase</fullName>
            <ecNumber evidence="3">3.5.99.6</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">nagB</name>
        <name evidence="6" type="ORF">A0J61_11946</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>alpha-D-glucosamine 6-phosphate + H2O = beta-D-fructose 6-phosphate + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:12172"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:57634"/>
            <dbReference type="ChEBI" id="CHEBI:75989"/>
            <dbReference type="EC" id="3.5.99.6"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the glucosamine/galactosamine-6-phosphate isomerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.5.99.6" evidence="3"/>
    <dbReference type="EMBL" id="LUGH01002744">
        <property type="protein sequence ID" value="OBZ65062.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7LJS8"/>
    <dbReference type="STRING" id="101091.A0A1C7LJS8"/>
    <dbReference type="InParanoid" id="A0A1C7LJS8"/>
    <dbReference type="OrthoDB" id="7663298at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004342">
        <property type="term" value="F:glucosamine-6-phosphate deaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042802">
        <property type="term" value="F:identical protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006043">
        <property type="term" value="P:glucosamine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006046">
        <property type="term" value="P:N-acetylglucosamine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019262">
        <property type="term" value="P:N-acetylneuraminate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1360">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006148">
        <property type="entry name" value="Glc/Gal-6P_isomerase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004547">
        <property type="entry name" value="Glucosamine6P_isomerase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037171">
        <property type="entry name" value="NagB/RpiA_transferase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11280">
        <property type="entry name" value="GLUCOSAMINE-6-PHOSPHATE ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11280:SF5">
        <property type="entry name" value="GLUCOSAMINE-6-PHOSPHATE ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01182">
        <property type="entry name" value="Glucosamine_iso"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100950">
        <property type="entry name" value="NagB/RpiA/CoA transferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glucosamine/galactosamine-6-phosphate isomerase" evidence="5">
        <location>
            <begin position="8"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000644"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005526"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012680"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01182"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OBZ65062.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="98" mass="11611" checksum="FE820D033A867B95" modified="2016-11-30" version="1" fragment="single">MRLVIREDYDEVTFYVANYIKERIRQFSPSASHPFVLGLPTGSSPINVYKHLVQMHKAGEISFKHVITFNMDEYVGLPRDHPESYHSFMWKHLFMHVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MTC2</accession>
    <name>A0A1C7MTC2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_11831</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01002554">
        <property type="protein sequence ID" value="OBZ80120.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MTC2"/>
    <dbReference type="InParanoid" id="A0A1C7MTC2"/>
    <dbReference type="OrthoDB" id="2271122at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ80120.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="135" mass="16035" checksum="799820EDCB3A31A4" modified="2016-11-30" version="1">MQSVSEFITLSEIISDNDMDTSSDDPMEDDEQEEMEIEHFSLSEEWMEKIRRIGNDSLSYVCEYMEVDLIEEENEDFFGDVFLFAELMPLRKRHTALNVRRGSYRKYTPKQVEKLFDLTIEEGFTTKSCSFSHWD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MTH1</accession>
    <name>A0A1C7MTH1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_11788</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01002493">
        <property type="protein sequence ID" value="OBZ80163.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7MTH1"/>
    <dbReference type="InParanoid" id="A0A1C7MTH1"/>
    <dbReference type="OrthoDB" id="2276327at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31912">
        <property type="entry name" value="IP13529P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31912:SF34">
        <property type="entry name" value="NOTOCHORD-RELATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="263"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ80163.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="263" mass="29836" checksum="76E1BEC21C1139DF" modified="2016-11-30" version="1" fragment="single">MIVGAQLLWIEADSPCHSELCGLLGLTTLYPCRKCYFLLRRGAGAPTIIAASDRSSFIANALEENVTTKASDLSFKNRGTDDLLRLNAYNPQKDTPTEILHTVLLGIXKYLVRDLVKLVLSKPETKQLNDALKQYKISEGFSRQFNKEITHCGSYLGRDFKILVQILPIILSHIFCDAQTLLFVVVRQVTRGFSRFVNEVDTAAKDLITCLHDYDENCTLQDHKKYTLKLKIHFLTHLAEDITRFGTALNFETEKGEQFNKHV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MTH8</accession>
    <name>A0A1C7MTH8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_11789</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01002494">
        <property type="protein sequence ID" value="OBZ80162.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MTH8"/>
    <dbReference type="InParanoid" id="A0A1C7MTH8"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="13"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="42"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ80162.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="51" mass="5861" checksum="C5A3DD567B36DE11" modified="2016-11-30" version="1" fragment="single">MSISNMVAQTVGHQDERQQRDKRAIGYARREDDHSDKEQDEQATIPSSSEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MUQ4</accession>
    <name>A0A1C7MUQ4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Putative acyl-CoA dehydrogenase IBR3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">IBR3</name>
        <name evidence="5" type="ORF">A0J61_11423</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01002017">
        <property type="protein sequence ID" value="OBZ80528.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MUQ4"/>
    <dbReference type="STRING" id="101091.A0A1C7MUQ4"/>
    <dbReference type="InParanoid" id="A0A1C7MUQ4"/>
    <dbReference type="OrthoDB" id="434771at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003995">
        <property type="term" value="F:acyl-CoA dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033539">
        <property type="term" value="P:fatty acid beta-oxidation using acyl-CoA dehydrogenase"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.140.10">
        <property type="entry name" value="Butyryl-CoA Dehydrogenase, subunit A, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050741">
        <property type="entry name" value="Acyl-CoA_dehydrogenase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036250">
        <property type="entry name" value="AcylCo_DH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009075">
        <property type="entry name" value="AcylCo_DH/oxidase_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48083:SF13">
        <property type="entry name" value="ACYL-COA DEHYDROGENASE FAMILY MEMBER 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48083">
        <property type="entry name" value="MEDIUM-CHAIN SPECIFIC ACYL-COA DEHYDROGENASE, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00441">
        <property type="entry name" value="Acyl-CoA_dh_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47203">
        <property type="entry name" value="Acyl-CoA dehydrogenase C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Acyl-CoA dehydrogenase/oxidase C-terminal" evidence="4">
        <location>
            <begin position="9"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="129"/>
            <end position="148"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OBZ80528.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="148" mass="16370" checksum="1A54FDB42C7A270F" modified="2016-11-30" version="1">MLVRVTDPSRRTFGKFLSEHGTVVADIAQSRIEIDQTRYLVLSAAQKIDQDKAKGAMKEIGMAKIASPNMLLRVLDRSMQAHGAGGISQDFPLAMFYASARTLRYADGPDEVHRNQIGKVELRRAEALQQKTAAQKKKSDLLASQSKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-06-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MUR3</accession>
    <name>A0A1C7MUR3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_11455</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01002049">
        <property type="protein sequence ID" value="OBZ80497.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="InParanoid" id="A0A1C7MUR3"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ80497.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="148" mass="16949" checksum="7BAEB93375ED7B43" modified="2016-11-30" version="1" fragment="single">NDERKTGNAIKRKPXADDVKEALGKLLPEVPPEEVYNSVLKXCTERSDEVIVSLYHGMPFSWKRVPTTIRGKMYNRASELIQQTHHIDMGLCESNWIVKTLVATGYQNRFSNLDTSEIIDSEGEEVIPQQAQKIEFEDQLGFMTVTRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MV20</accession>
    <name>A0A1C7MV20_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Phosphoenolpyruvate carboxykinase (ATP)</fullName>
            <ecNumber evidence="3">4.1.1.49</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">acu-6_2</name>
        <name evidence="11" type="ORF">A0J61_11259</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>oxaloacetate + ATP = phosphoenolpyruvate + ADP + CO2</text>
            <dbReference type="Rhea" id="RHEA:18617"/>
            <dbReference type="ChEBI" id="CHEBI:16452"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="4.1.1.49"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Carbohydrate biosynthesis; gluconeogenesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.1.1.49" evidence="3"/>
    <dbReference type="EMBL" id="LUGH01001837">
        <property type="protein sequence ID" value="OBZ80692.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MV20"/>
    <dbReference type="STRING" id="101091.A0A1C7MV20"/>
    <dbReference type="InParanoid" id="A0A1C7MV20"/>
    <dbReference type="OrthoDB" id="184182at2759"/>
    <dbReference type="UniPathway" id="UPA00138"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004612">
        <property type="term" value="F:phosphoenolpyruvate carboxykinase (ATP) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006094">
        <property type="term" value="P:gluconeogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd00484">
        <property type="entry name" value="PEPCK_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.170.8.10:FF:000001">
        <property type="entry name" value="Phosphoenolpyruvate carboxykinase (ATP)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.449.10:FF:000002">
        <property type="entry name" value="Phosphoenolpyruvate carboxykinase [ATP]"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.228.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.449.10">
        <property type="entry name" value="Phosphoenolpyruvate Carboxykinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.8.10">
        <property type="entry name" value="Phosphoenolpyruvate Carboxykinase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00453">
        <property type="entry name" value="PEPCK_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001272">
        <property type="entry name" value="PEP_carboxykinase_ATP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013035">
        <property type="entry name" value="PEP_carboxykinase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008210">
        <property type="entry name" value="PEP_carboxykinase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015994">
        <property type="entry name" value="PEPCK_ATP_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00224">
        <property type="entry name" value="pckA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006820">
        <property type="entry name" value="PRK09344.1-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006821">
        <property type="entry name" value="PRK09344.1-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30031:SF0">
        <property type="entry name" value="PHOSPHOENOLPYRUVATE CARBOXYKINASE (ATP)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30031">
        <property type="entry name" value="PHOSPHOENOLPYRUVATE CARBOXYKINASE ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01293">
        <property type="entry name" value="PEPCK_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006294">
        <property type="entry name" value="PEP_crbxkin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF68923">
        <property type="entry name" value="PEP carboxykinase N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53795">
        <property type="entry name" value="PEP carboxykinase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00532">
        <property type="entry name" value="PEPCK_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="5" id="KW-0312">Gluconeogenesis</keyword>
    <keyword evidence="11" id="KW-0418">Kinase</keyword>
    <keyword evidence="9" id="KW-0456">Lyase</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0808">Transferase</keyword>
    <feature type="non-terminal residue" evidence="11">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004742"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00021932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00047371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="OBZ80692.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="486" mass="53867" checksum="384EB48A33946F81" modified="2016-11-30" version="1" fragment="single">ALCAYSGKKTGRSPKDKRIVEEETSQKDIWWGPVNTPISEKVFLINRERAIDYLNTRPRLYVFDGFAGWDPKYRIKVRVVASRAYHLLFMRNMLIRPTDEELESFGTPDFTIFNAGEFPANRYTTGMTSTTSVSVNFKRNEMVILGSEYAGEMKKGIFTVMHYLMPKAGVLSLHSSANEGPDGDVSLFFGLSGTGKTTLSADPKRMLIGDDEHCWSDDGIFNIEGGCYAKCIDLSAEKEPDIFNAIRFGAILENVVLDEETREVDYSDDFLTENTRCAYPIYHIPNAKLPCMGGHPKNIILLTCDAFGVLPPVSKLTAEQAMYHFISGYTTKVPGTEDGIVEPQATFSACFGAPFLVLHPQRYATMLAQKMSQHKADAWLINTGWIGGSAATSKRCPLKYTRAILDAIHSGELANADYEDLAIFNLSIPKAVTGVPSELLNPKTAWNGTAEEFDGSLRKVGQMFIENFKTYEDQAAPETLAAGPKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MW31</accession>
    <name>A0A1C7MW31_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_10855</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001450">
        <property type="protein sequence ID" value="OBZ81095.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MW31"/>
    <dbReference type="STRING" id="101091.A0A1C7MW31"/>
    <dbReference type="InParanoid" id="A0A1C7MW31"/>
    <dbReference type="OrthoDB" id="2287989at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ81095.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="142" mass="15896" checksum="3532DB2516280E6F" modified="2016-11-30" version="1" fragment="single">MLTSLSRIVYNLANIETALASTEVPGVSSLPLNETMLIAKEWKECFDRISELRATKWIKKRSRSAENLIMGESRRGQHTPTRTVRISQKDSKKIGCRGTLSILQYVQNPGVVEIKMSMGHVNHVPGSNSDIRTLSLTRETVT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MWK8</accession>
    <name>A0A1C7MWK8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_10686</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001318">
        <property type="protein sequence ID" value="OBZ81265.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MWK8"/>
    <dbReference type="InParanoid" id="A0A1C7MWK8"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="55"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="55"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="72"/>
            <end position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ81265.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="146" mass="16409" checksum="904B9D54CD92F326" modified="2016-11-30" version="1">MLIEEVYLSEKRKIDDTDLGGATELRNVRVFRSGKAIPTPNLKCTTVLDANLKSMPSSSLESEPYLPEKLATETNDSNNSRKVQVNPHHPLKSTDHRDHEDLTVKSKVDQVLDKLFDNATVVFIMNEMALISPTARTGFKSWLTKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MWU1</accession>
    <name>A0A1C7MWU1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_10655</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001293">
        <property type="protein sequence ID" value="OBZ81297.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MWU1"/>
    <dbReference type="STRING" id="101091.A0A1C7MWU1"/>
    <dbReference type="InParanoid" id="A0A1C7MWU1"/>
    <dbReference type="OrthoDB" id="5598606at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ81297.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="78" mass="8751" checksum="43F9467834B31EC6" modified="2016-11-30" version="1">MIQEDLSSSDCRIGGYDENGNSIIVKIDELKFGKRKHFRGHHVGGVWVVGGVERTPQRRCFLVVVPDQSARTLLSIIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MWU7</accession>
    <name>A0A1C7MWU7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Integrase catalytic domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">A0J61_10595</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001256">
        <property type="protein sequence ID" value="OBZ81355.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MWU7"/>
    <dbReference type="STRING" id="101091.A0A1C7MWU7"/>
    <dbReference type="InParanoid" id="A0A1C7MWU7"/>
    <dbReference type="OrthoDB" id="2260752at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015074">
        <property type="term" value="P:DNA integration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd09274">
        <property type="entry name" value="RNase_HI_RT_Ty3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01647">
        <property type="entry name" value="RT_LTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.20.370:FF:000001">
        <property type="entry name" value="Retrovirus-related Pol polyprotein from transposon 17.6-like protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.270:FF:000003">
        <property type="entry name" value="Transposon Ty3-G Gag-Pol polyprotein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.340.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.370">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.10.10">
        <property type="entry name" value="HIV Type 1 Reverse Transcriptase, subunit A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043502">
        <property type="entry name" value="DNA/RNA_pol_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001584">
        <property type="entry name" value="Integrase_cat-core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041588">
        <property type="entry name" value="Integrase_H2C2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050951">
        <property type="entry name" value="Retrovirus_Pol_polyprotein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000477">
        <property type="entry name" value="RT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041577">
        <property type="entry name" value="RT_RNaseH_2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37984">
        <property type="entry name" value="PROTEIN CBG26694"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37984:SF5">
        <property type="entry name" value="PROTEIN NYNRIN-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17921">
        <property type="entry name" value="Integrase_H2C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17919">
        <property type="entry name" value="RT_RNaseH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00665">
        <property type="entry name" value="rve"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00078">
        <property type="entry name" value="RVT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56672">
        <property type="entry name" value="DNA/RNA polymerases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50994">
        <property type="entry name" value="INTEGRASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Integrase catalytic" evidence="3">
        <location>
            <begin position="608"/>
            <end position="683"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="752"/>
            <end position="771"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50994"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OBZ81355.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="771" mass="87249" checksum="5CFD9109C9506C89" modified="2016-11-30" version="1" fragment="single">TIEREYEVMNLTNSNEYDLSIGTDFMSALGIGIYGLPMRFDDQDSNEERLEVDRRFNNRSDLLESIQRENESKENNPALSPQEFEKVMGYINKFIDENQAIPKGSFCTIPESVVCLDTPENATAYRAPYLIPIAMQEVVDKQVQEWLDNGIIEKAPANTAWNTPLTLVSKTNGKGETTGYRVCHDPRMLNLLLKSIDRMPLPVIGELFEDLKGANYKPIGTVFGIKHVSSQFQRTMSIPLEGLTFVRFFVDDIVVASKTAEEHREHLKQVIQRLTKVNLKLNPKKCHFFQKEIHLLGFHISPAGITMDRRKLVNVLDFSQPKTGKDIQRYCGLINYFRNLIPNVSTIMAPLDSLRNEKSIVHLRNEQHQIAFDNLKKALLSDTVLSYPDMNAKLCISCDASLTGIGAVLYQVIDGKTKYISFVAKSLSKSERNYSATKRELLAVVFALKRFHKYVYGSHFTLFTDHKALTYLHTQRVANLMMIAWMDTILQYDFKIVHLPGVSNVLPDALSRLFEGSSSLLNELGGDNWTKSIMRNGAVSMEPIPDVLSVDEHLKGHFGAKAMVQVSKRKGIYWNKLQSQANDLVQACVQCQRHNISRKDYSPLRPVTAPIPGDSWRVDLTGPFTMSTRGNEYLLVMIDIASKFYVLRPIPDKSAATVALHILDIISTYGPMRKLQSDNGREFYHPRANGASERAAQAAVNTIKKLVIVNVADWDSKVPAAQLFLNSKYNARTKSTPFSLMFGRNPNDFKDFSQEKDSATAVEIQRELQEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MX34</accession>
    <name>A0A1C7MX34_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Reverse transcriptase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_10644</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001288">
        <property type="protein sequence ID" value="OBZ81308.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7MX34"/>
    <dbReference type="InParanoid" id="A0A1C7MX34"/>
    <dbReference type="OrthoDB" id="2282267at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.10.10">
        <property type="entry name" value="Endonuclease/exonuclease/phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036691">
        <property type="entry name" value="Endo/exonu/phosph_ase_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56219">
        <property type="entry name" value="DNase I-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ81308.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="439" mass="48776" checksum="57F0BCA3385A5C7B" modified="2016-11-30" version="1">MKIXAVNVHCVYFSPSISDDLVISSLKQISLSSDAIICGNFSSRMGTLAGDSRTNLRGVRLQSFCERCTLAVLNSTLAHGIVTFSAFRQEAKRSSILDLFLTNISSWNMFYLNLSIETSLPLGLDHRLMALSFNYAPPLRSGSNSDGTLVPRRLWSLLRLGELELSALFRSKFSFLVSGLSTSLVADPSPTRSDINAMNAAVNECFYVALYGSIGAKTEEIETAAGKRDQCYSRWRHAVGVDKAFWWTQHKDAHREFRRLVSAVKRLSWKNFCDSLEKDFQKAISTLARYKRRRDCSLFFIHADGRQAATSIMADHLASVYSGSLLPSDSRSPPVPDLSSLAPFMLSDSDKDVFAADAIMDHIKRCICGKLLYRLVVAFLDIKAAYDTVDRRVIWDALSFTTLPRPFLAILVNLFDEVQVSVLIANHTSAPFAPATGVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MX46</accession>
    <name>A0A1C7MX46_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_10554</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001232">
        <property type="protein sequence ID" value="OBZ81397.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MX46"/>
    <dbReference type="InParanoid" id="A0A1C7MX46"/>
    <dbReference type="OrthoDB" id="2429771at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ81397.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="507" mass="56443" checksum="5968632F8C2D68FA" modified="2016-11-30" version="1">MLCLKEEQKKFIINEEAPFLLVFVHRFIGHLKITNEGSESLHQTLKRRHKDLLTLYRPEIDADFYGMLDSSTFRCFLKKRAREDDAPAPATSTAADTTIASDIAPVTATAIAPATATAIAPATATDIDTDTSPATATATNTDTFTTTESSISAAMTLISNPVATHPVTSNWMCHGHNVIDKLSTLRRAALTAKELGKKLSATQKLMLNHIYFVSSKRQKSVGKFLPHQVHLFLNNLNSGALPTVPDVVKTWVNELEAIKANHVEEEATLEDELTKLLSKKALSFLIQASEADDDVLATYARTINEVVANHKRWCHEEMAETMFISLFFSPIARNTFERLNANVFKIDMQDKHMNGYAVKPDYLVSLFSGSGEELNIYSMEAKTPEANKGDLDFIKLANTMKAMVDEFVSRGCLLPHARSFGTLLHGDTMISYEMSLENEGIYIMKELNAVQMPCLIGDLSLLLPMINDIIHVCEKVKEHADAIIGLGMDKTKHPFQRPTNWRVREAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MXJ0</accession>
    <name>A0A1C7MXJ0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Transposon Tf2-9 polyprotein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">Tf2-9_0</name>
        <name evidence="9" type="ORF">A0J61_10394</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001152">
        <property type="protein sequence ID" value="OBZ81557.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="FunCoup" id="A0A1C7MXJ0">
        <property type="interactions" value="2"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7MXJ0"/>
    <dbReference type="InParanoid" id="A0A1C7MXJ0"/>
    <dbReference type="OrthoDB" id="2275801at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003964">
        <property type="term" value="F:RNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015074">
        <property type="term" value="P:DNA integration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00303">
        <property type="entry name" value="retropepsin_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd09274">
        <property type="entry name" value="RNase_HI_RT_Ty3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01647">
        <property type="entry name" value="RT_LTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.10:FF:000032">
        <property type="entry name" value="Retrovirus-related Pol polyprotein from transposon 297-like Protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.270:FF:000020">
        <property type="entry name" value="Transposon Tf2-6 polyprotein-like Protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.340.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.10.10">
        <property type="entry name" value="HIV Type 1 Reverse Transcriptase, subunit A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043502">
        <property type="entry name" value="DNA/RNA_pol_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001584">
        <property type="entry name" value="Integrase_cat-core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041588">
        <property type="entry name" value="Integrase_H2C2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005162">
        <property type="entry name" value="Retrotrans_gag_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050951">
        <property type="entry name" value="Retrovirus_Pol_polyprotein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000477">
        <property type="entry name" value="RT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041373">
        <property type="entry name" value="RT_RNaseH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37984">
        <property type="entry name" value="PROTEIN CBG26694"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37984:SF5">
        <property type="entry name" value="PROTEIN NYNRIN-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17921">
        <property type="entry name" value="Integrase_H2C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03732">
        <property type="entry name" value="Retrotrans_gag"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17917">
        <property type="entry name" value="RT_RNaseH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00665">
        <property type="entry name" value="rve"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00078">
        <property type="entry name" value="RVT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56672">
        <property type="entry name" value="DNA/RNA polymerases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50994">
        <property type="entry name" value="INTEGRASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50878">
        <property type="entry name" value="RT_POL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0540">Nuclease</keyword>
    <keyword evidence="2" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0695">RNA-directed DNA polymerase</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Reverse transcriptase" evidence="7">
        <location>
            <begin position="536"/>
            <end position="721"/>
        </location>
    </feature>
    <feature type="domain" description="Integrase catalytic" evidence="8">
        <location>
            <begin position="1076"/>
            <end position="1236"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="1376"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50994"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OBZ81557.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="1376" mass="157610" checksum="BE209E4232A5CF76" modified="2016-11-30" version="1" fragment="single">MSRMENNAGVPKIEENYKDNMAELIRQFTSILSENKQVRIKEPNTYDGTRDALLIDGWIRSIERYTEFHGWSTEKSCLFATTLLRDRADAWYRTLEVSNDTPTSWLEFKRLLIDFFRPDNSVRIARDKLAALRQTGNLVDYVNAFMDIKLAIPGMTDEEACDKFVRGLALKSMRAHIRQYEADTLKDAVRAALSYDSAQREEDFVRPVNGVRSKVVDDPMELDALDSRRGNFSNYHRGGGFSRTGGSARGDFGSRRFGGNSGGSNNLCYYCDKPGHMKRNLNVVEDQEVQLHDDNDNIPENKNLIDLDPYTIAPLDNELFPQKTDELKYLGELNSIATSLPLYCASFNDKTIKILIDSDQLISVHDRQVETAGGTIAQIKYKVQMKVNLNGYDDLVTAYVFPTKFDLILGRSWLKHIELKPCVNSKSVDYTKLNYLISHKQANKSIKKGADSFLLYIKPTSDQVDKNPQLQNDSYWDELVREFGTVFQDSLPGLPPDRGIEHVIDVGDARPISRPPYKMSPLELQELQKQLKELLKLGLIRPSSSPWGAPVLFVRKKPDPGSHKPGALRMCIDYRMLNKYTIRNSSSLPRIDECLEQLSGKKYFSSLDLKSGYHQIRINERDIPLTAFNTRYGQFAWNVLPMGLCNAPPVFQTMMNKVLADCIDKFALVYLDDILIFSDNWEDHKKHVRHVIELLKKEKLVANLKKCEFGKRELTFVGYRISAEGISPSPEKVKVIQEWPRMTNVQEVRQFIGFAQFYKRLIPNFATIAAPLTDLTRGNGLKKRPIVWNDDCQRSFDQLKKLLSSSPVLQVVDMDKPFRIEVDASDRGCGAVCLQPAADGSDLWKPIAFESKKFSEAERKYPAQERELLGILHALRTWRCYIDGCPKGYVVYSDHLPLQYFRTKDKPPSRLVRWISELELFSPTILYKPGKDNHIPDALSRMNYDSPDVPPAADSMEPDYLYAAWDKLSPGLRSDWPLLLLPQNREKVKSDEVKHILDREEKNFDVPFLPFSERADTVAKYHNSFGHAGYKSMLKMLVPRFWWPSLRLDLQNWLSTCPSCQVNSRRTRAHQDEMHPLKVPTAFDRWHLDFLDLPETVKGNRWLLIGVDYATNWPVARALPVASREAVADFIYEEIVMRFGVPSEIVTDRGANFTSGLVKTYLRKVGVNHKLTSAYHPRSNGKVERFNGVIKQMLRKYTNGALHRWDDFVNAALWACRIRVHSTTGFSPFYLTYGREPRLPGDVLQPYIDATVFKDPRTVADHTARELAQLGQHRAAAEFRLKAMAEKDKEKWDAAIKKVTFEPGDLVMLTHEGRFGLEPKFKGPYVVVKVFPDFGTYQLQTISGEPLKSLVHVDRMKIAKGAKPESPWYDPTVERR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MXJ7</accession>
    <name>A0A1C7MXJ7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">FAR1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_10326</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001119">
        <property type="protein sequence ID" value="OBZ81625.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MXJ7"/>
    <dbReference type="InParanoid" id="A0A1C7MXJ7"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ81625.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="151" mass="17377" checksum="8EE56F0487BD2CAB" modified="2016-11-30" version="1">MNSQLSLSESQLTVTNFPVSQNAIIPCKFNEWDSSSDEEYLSSDKEEVPTEKVFFVGANFESMEEIRSKAQDIGSQFNCPITTVNEKGTRHYKSGRHECPMRVYVSKGRDIEKPREVRRITIEHNHSITKDLSAYPIFRKLAAEDFDFTCE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-06-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MXV4</accession>
    <name>A0A1C7MXV4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_10313</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001114">
        <property type="protein sequence ID" value="OBZ81638.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MXV4"/>
    <dbReference type="InParanoid" id="A0A1C7MXV4"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ81638.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="108" mass="12099" checksum="C897509FC7245731" modified="2016-11-30" version="1">MGKGTLALDARSMGWSHLVADGGTRVLRRIGKRYKELLIAPTTKLGGVGPLVDIDGTRNQAKYIEALSENFQPWLMKLQSKHDNALSFNKMNLRVILELWHVTGRTII</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MYY8</accession>
    <name>A0A1C7MYY8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_09973</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000988">
        <property type="protein sequence ID" value="OBZ81978.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MYY8"/>
    <dbReference type="InParanoid" id="A0A1C7MYY8"/>
    <dbReference type="OrthoDB" id="2216037at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ81978.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="222" mass="26449" checksum="A649705833E1D99C" modified="2016-11-30" version="1">MTMENIFKKLKRGYRKLFADWVRNKMHQKESKDCLEKITLAHRATPMTQYNIRESIPLCQLKRYSLSQSTKIQFSRQRRTLPFQPLYEIEWQKNKWLQLDLDTSKQIERMRLQGHTHLAIRKDSIIRQHMEYAFKEDTDVVLELMFTGPTERQSITCQYHANPLQFAIRRAYLWRIEYDIGFAYLPSWVDQDVCCHHTLLDAHSALTSMTLSCSMGSSIESH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-06-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MZ81</accession>
    <name>A0A1C7MZ81_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_11497</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01002115">
        <property type="protein sequence ID" value="OBZ80454.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MZ81"/>
    <dbReference type="InParanoid" id="A0A1C7MZ81"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="38"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="253"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ80454.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="253" mass="27868" checksum="6324231DD32A06F1" modified="2016-11-30" version="1" fragment="single">MSNLPPVVVASPRSVAPSAVCAAARPTCHAVPLVPVVSAAANAEQKALEEKVRALEIRLAQIEALMMDTNSAPGPGRGHGRNPMHVRVVREAFEVAKNTYGLEFHQDFSMKNRLVNLAVYIKIIELSADAIKTLAGLAQTQTLAPVVMGSLDNRIRNRFKNARRTSRTAALPALDRQEYKDNDTKRKRLSRKKNNRDACFKKAKDILSVGFGTAENCEACIQAAYMFDEEEGSHRPGTGRSFRVLVPSWRSDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MZD6</accession>
    <name>A0A1C7MZD6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Asparagine-rich zinc finger protein AZF1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">AZF1</name>
        <name evidence="11" type="ORF">A0J61_09753</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000929">
        <property type="protein sequence ID" value="OBZ82197.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MZD6"/>
    <dbReference type="STRING" id="101091.A0A1C7MZD6"/>
    <dbReference type="InParanoid" id="A0A1C7MZD6"/>
    <dbReference type="OrthoDB" id="6077919at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000100">
        <property type="entry name" value="Zinc finger 45-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000072">
        <property type="entry name" value="zinc finger protein 143 isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:001289">
        <property type="entry name" value="Zinc finger protein 574"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050329">
        <property type="entry name" value="GLI_C2H2-zinc-finger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19818:SF162">
        <property type="entry name" value="GASTRULA ZINC FINGER PROTEIN XLCGF57.1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19818">
        <property type="entry name" value="ZINC FINGER PROTEIN ZIC AND GLI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="7" id="KW-0804">Transcription</keyword>
    <keyword evidence="6" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 9" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="10">
        <location>
            <begin position="45"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="10">
        <location>
            <begin position="81"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="10">
        <location>
            <begin position="111"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="10">
        <location>
            <begin position="141"/>
            <end position="170"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="OBZ82197.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="170" mass="19896" checksum="192E9E82292C7EA8" modified="2016-11-30" version="1">MSYPNPYPPQTATRIQQIYNTNYLSEQPYHETTSPVEHYKSRKLYTCHEPGCSEFFDHSNGLRMHQRNRHGEDSSRQGRPYVCPYAECGKSFTQYGNLKTHSRKHTGERPYHCSYHGCDKSFTQLGNLKTHEKIHWPVKPFTCVYPNCGKGFTQRGNLKTHQVKVHQMTQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MZD9</accession>
    <name>A0A1C7MZD9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8 11">Cystathionine beta-synthase</fullName>
            <ecNumber evidence="4 11">4.2.1.22</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">cysB_1</name>
        <name evidence="13" type="ORF">A0J61_09755</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9 11">
            <text>L-homocysteine + L-serine = L,L-cystathionine + H2O</text>
            <dbReference type="Rhea" id="RHEA:10112"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:33384"/>
            <dbReference type="ChEBI" id="CHEBI:58161"/>
            <dbReference type="ChEBI" id="CHEBI:58199"/>
            <dbReference type="EC" id="4.2.1.22"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 11">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Amino-acid biosynthesis; L-cysteine biosynthesis; L-cysteine from L-homocysteine and L-serine: step 1/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 11">Belongs to the cysteine synthase/cystathionine beta-synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.22" evidence="4 11"/>
    <dbReference type="EMBL" id="LUGH01000929">
        <property type="protein sequence ID" value="OBZ82193.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MZD9"/>
    <dbReference type="STRING" id="101091.A0A1C7MZD9"/>
    <dbReference type="InParanoid" id="A0A1C7MZD9"/>
    <dbReference type="OrthoDB" id="728at2759"/>
    <dbReference type="UniPathway" id="UPA00136">
        <property type="reaction ID" value="UER00201"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004122">
        <property type="term" value="F:cystathionine beta-synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006535">
        <property type="term" value="P:cysteine biosynthetic process from serine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019343">
        <property type="term" value="P:cysteine biosynthetic process via cystathionine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01561">
        <property type="entry name" value="CBS_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd04608">
        <property type="entry name" value="CBS_pair_CBS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1100:FF:000003">
        <property type="entry name" value="Cystathionine beta-synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1100:FF:000118">
        <property type="entry name" value="Related to CYS4-cystathionine beta-synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1100">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.580.10">
        <property type="entry name" value="CBS-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046353">
        <property type="entry name" value="CBS_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000644">
        <property type="entry name" value="CBS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046342">
        <property type="entry name" value="CBS_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050214">
        <property type="entry name" value="Cys_Synth/Cystath_Beta-Synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005857">
        <property type="entry name" value="Cysta_beta_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001216">
        <property type="entry name" value="P-phosphate_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001926">
        <property type="entry name" value="TrpB-like_PALP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036052">
        <property type="entry name" value="TrpB-like_PALP_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01137">
        <property type="entry name" value="cysta_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10314">
        <property type="entry name" value="CYSTATHIONINE BETA-SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00571">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00291">
        <property type="entry name" value="PALP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00116">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54631">
        <property type="entry name" value="CBS-domain pair"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53686">
        <property type="entry name" value="Tryptophan synthase beta subunit-like PLP-dependent enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51371">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00901">
        <property type="entry name" value="CYS_SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="6 10 11" id="KW-0129">CBS domain</keyword>
    <keyword evidence="11" id="KW-0198">Cysteine biosynthesis</keyword>
    <keyword evidence="7 11" id="KW-0456">Lyase</keyword>
    <keyword evidence="5 11" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CBS" evidence="12">
        <location>
            <begin position="369"/>
            <end position="431"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012041"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00026192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00047490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU361204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="OBZ82193.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="496" mass="54346" checksum="6596B4408C8649F2" modified="2016-11-30" version="1">MSTEIKKIFEQYNHKHNTAPAPKISNSILENIGRTPLVRINKIAKEEGLKCELLAKCEYFNAGGSVKDRIAYRMVEEAEKAGTITPGVSTIIEPTSGNTGIGLALAGAVKGYRVIITLPEKMSQEKVDVLKALGAEIIRTPTEAAWDAPESHIGVAKKLRDEIPNAVILDQYANPYNPVAHYDTTAEEILEQCDGKIDMLVAGAGTGGTITGLAQKLKEKCPNIKIVGVDPVGSILAVPESLNTEAGSYQVEGIGYDFIPDVLKRELVDVWIKSEDKPSFLMSRRLIRQEGILCGGSSGTAMYAAIQAAKELKEGQRCVVMLPDSVRNYMTKFLNDDWMRQRGFTDEKFENESFETKAKKDYAGATVADLKLAAAVTIDGETTCKEAIDVMEQNGFDQLPVTAGPQHRLRGLVTLGNILSRMASGRAQPDSPVTDVMFHFTKGSKKFEEITLQTPLDNLTRFFETNSSALITEDHKVKHVVTKVDLLSYLVKHVKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MZE1</accession>
    <name>A0A1C7MZE1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="8">AP-3 complex subunit beta-2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">AP3B2</name>
        <name evidence="8" type="ORF">A0J61_09809</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the adaptor complexes large subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000943">
        <property type="protein sequence ID" value="OBZ82141.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MZE1"/>
    <dbReference type="FunCoup" id="A0A1C7MZE1">
        <property type="interactions" value="351"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7MZE1"/>
    <dbReference type="InParanoid" id="A0A1C7MZE1"/>
    <dbReference type="OrthoDB" id="10254310at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030123">
        <property type="term" value="C:AP-3 adaptor complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016192">
        <property type="term" value="P:vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026740">
        <property type="entry name" value="AP3_beta"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026739">
        <property type="entry name" value="AP_beta"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002553">
        <property type="entry name" value="Clathrin/coatomer_adapt-like_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11134">
        <property type="entry name" value="ADAPTOR COMPLEX SUBUNIT BETA FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01602">
        <property type="entry name" value="Adaptin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037096">
        <property type="entry name" value="AP3_complex_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0653">Protein transport</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Clathrin/coatomer adaptor adaptin-like N-terminal" evidence="7">
        <location>
            <begin position="56"/>
            <end position="609"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="269"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="685"/>
            <end position="708"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="745"/>
            <end position="789"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="692"/>
            <end position="703"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="750"/>
            <end position="787"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004308"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01602"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OBZ82141.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="803" mass="89836" checksum="96DFD9D0A4331ECB" modified="2016-11-30" version="1">MEVSDYINTAKTFAEKAAKLSQKMSQGLVDNARELGFPGSESGAQYFDTSEEKMRNIKRQLDSKNDREKLDGLKRLIAMISKGRDVSEFFPDVVKNVVSQNIEVRKLVYIFLLRYAEQEPDLALLSINSFQKDLSDKNQIIRAMALRVMSGIRVPVISPIVLLGIKKCATDPSPYVRKAAAHAIPKCYSLDSSQKEALVEIIASLLKDRSNLVIGSTLMAFNEVCPNRFDLIHPCFRKLCSMLGDCDEWGQMSILGVLLRYGRNQFLNPNPKGEDESRVAPKKKPTTTTARVGKSFYSSDSSEEDQDDHDAKEIEEVDLDVDHELLLKSCAPLLQSRNSGVVLAVAKLYYYLAPVADAEKIAKPLVRLLRSHREQSYVVLSNIATMAIKRPYLFESSLQQFYAQSSEPVFIRDTKLDILTTIANEANIHSLLAELQQYVKSPNKDFVAATVQAIGRCATSVPTAMDQCLRLLMRLLRSKNELVVAESVLVLTRLLQVPSEERSKSVIMLVKLLDTIQVSMARANILWLVGQYAEALPNVGPDVLRQAVKRFIDEDNATKLQTITLSAKLICLNPTHPTLNQLNQYLLNLARYDTSYDVRDRARFLRALTLQSVDEKQGLQQIKQHLPSILLSHKQPPVVQPTDSQNASDYNIGSLSLLAHQPLPGYEPLADYPEERPDPSVRDVEELEGWSGSRTVATETGFGSDSYRRGTTALSGVEAMGSSSLNSMYTSSAYKKKGNDYDLDAFYNESTEEEDSSASEEETSSEEEEEEEEEESSEEEETDEDESSCTLPTVYAVFCLVFI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MZU8</accession>
    <name>A0A1C7MZU8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Glutathione S-transferase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_10008</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001000">
        <property type="protein sequence ID" value="OBZ81946.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MZU8"/>
    <dbReference type="STRING" id="101091.A0A1C7MZU8"/>
    <dbReference type="InParanoid" id="A0A1C7MZU8"/>
    <dbReference type="OrthoDB" id="249703at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00299">
        <property type="entry name" value="GST_C_family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00570">
        <property type="entry name" value="GST_N_family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1050.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010987">
        <property type="entry name" value="Glutathione-S-Trfase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036282">
        <property type="entry name" value="Glutathione-S-Trfase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040079">
        <property type="entry name" value="Glutathione_S-Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004045">
        <property type="entry name" value="Glutathione_S-Trfase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050983">
        <property type="entry name" value="GST_Omega/HSP26"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43968">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43968:SF6">
        <property type="entry name" value="GLUTATHIONE S-TRANSFERASE OMEGA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13410">
        <property type="entry name" value="GST_C_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13417">
        <property type="entry name" value="GST_N_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00019">
        <property type="entry name" value="Glutathione_Transferase_(cytos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47616">
        <property type="entry name" value="GST C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50405">
        <property type="entry name" value="GST_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50404">
        <property type="entry name" value="GST_NTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GST N-terminal" evidence="1">
        <location>
            <begin position="2"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="domain" description="GST C-terminal" evidence="2">
        <location>
            <begin position="82"/>
            <end position="221"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ81946.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="221" mass="25776" checksum="ACB52A80E2B1BD2D" modified="2016-11-30" version="1">MTNITLVGIPLSTFTRTLRMAFYHLKVDYRFEKAVPYSDNAYKYHPFGRVPSLVVKDKVLIESSVIREFIDTTIDSRLTPNSLDERLKMLQIVSALSDYVFHQVVAGVAKPRHYYESQGLSEEEIQQRLKKKLQKAGEVISAFDTLCSQQDPFLCGPELTWADYFVFPPFADLYSLPEAGFFQQKGPRVHAWYQQFKDREEVRYTYPKTFADIRDRKEAHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MZZ0</accession>
    <name>A0A1C7MZZ0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_09521</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000869">
        <property type="protein sequence ID" value="OBZ82430.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MZZ0"/>
    <dbReference type="InParanoid" id="A0A1C7MZZ0"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ82430.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="62" mass="7120" checksum="D01783CD2D247E76" modified="2016-11-30" version="1">MLDNLSDLCNKKAFKDDVVVEEFKPCVSALVDFTGCTKYSENMNRINEISSKMIILFPEKKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N0R0</accession>
    <name>A0A1C7N0R0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Enolase-phosphatase E1</fullName>
            <ecNumber evidence="6">3.1.3.77</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">2,3-diketo-5-methylthio-1-phosphopentane phosphatase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">enoph1</name>
        <name evidence="6" type="synonym">UTR4</name>
        <name evidence="7" type="ORF">A0J61_09269</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>5-methylsulfanyl-2,3-dioxopentyl phosphate + H2O = 1,2-dihydroxy-5-(methylsulfanyl)pent-1-en-3-one + phosphate</text>
            <dbReference type="Rhea" id="RHEA:21700"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:49252"/>
            <dbReference type="ChEBI" id="CHEBI:58828"/>
            <dbReference type="EC" id="3.1.3.77"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="6">Binds 1 Mg(2+) ion per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="6">Amino-acid biosynthesis; L-methionine biosynthesis via salvage pathway; L-methionine from S-methyl-5-thio-alpha-D-ribose 1-phosphate: step 3/6.</text>
    </comment>
    <comment type="pathway">
        <text evidence="6">Amino-acid biosynthesis; L-methionine biosynthesis via salvage pathway; L-methionine from S-methyl-5-thio-alpha-D-ribose 1-phosphate: step 4/6.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="6">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the HAD-like hydrolase superfamily. MasA/MtnC family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.77" evidence="6"/>
    <dbReference type="EMBL" id="LUGH01000813">
        <property type="protein sequence ID" value="OBZ82677.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N0R0"/>
    <dbReference type="FunCoup" id="A0A1C7N0R0">
        <property type="interactions" value="363"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N0R0"/>
    <dbReference type="InParanoid" id="A0A1C7N0R0"/>
    <dbReference type="OrthoDB" id="272500at2759"/>
    <dbReference type="UniPathway" id="UPA00904">
        <property type="reaction ID" value="UER00876"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043874">
        <property type="term" value="F:acireductone synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019509">
        <property type="term" value="P:L-methionine salvage from methylthioadenosine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01629">
        <property type="entry name" value="HAD_EP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1000:FF:000079">
        <property type="entry name" value="Enolase-phosphatase E1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.720.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03117">
        <property type="entry name" value="Salvage_MtnC_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023943">
        <property type="entry name" value="Enolase-ppase_E1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027511">
        <property type="entry name" value="ENOPH1_eukaryotes"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006439">
        <property type="entry name" value="HAD-SF_hydro_IA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01691">
        <property type="entry name" value="enolase-ppase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01549">
        <property type="entry name" value="HAD-SF-IA-v1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20371">
        <property type="entry name" value="ENOLASE-PHOSPHATASE E1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20371:SF1">
        <property type="entry name" value="ENOLASE-PHOSPHATASE E1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00702">
        <property type="entry name" value="Hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01133">
        <property type="entry name" value="C1.5.4:_Enolase-phosphatase_Li"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01129">
        <property type="entry name" value="C1.5:_HAD__Beta-PGM__Phosphata"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00044">
        <property type="entry name" value="enolase-phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00003">
        <property type="entry name" value="Haloacid_Dehalogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 6" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="2 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 6" id="KW-0486">Methionine biosynthesis</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="6">
        <location>
            <position position="10"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="12"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="146"/>
            <end position="147"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="180"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="206"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OBZ82677.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="248" mass="27822" checksum="1478FF463054E086" modified="2016-11-30" version="1">MSEYDTVIVDIEGTITPITFVKETLFPYVTSGLSAFLDRTWDSEELKHHIQLLREQAKQDVEANISEAVLIPTESETSIDQVKEAVKKTIEWQMKADRKIGALKSFQGFMWKEGYESGVLRGVVYDDVVPAFDQWKAAGKKIYIYSSGSVPAQKLLVGYSTKGDLSSYFSGYFDTSIGLKVESQSYKNIAEQIKEDQHHRILFITDNIKEVLAASEAGYQVVISDRPGNALLGPESEPFKIVTSFDQI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N0X5</accession>
    <name>A0A1C7N0X5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_09189</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000794">
        <property type="protein sequence ID" value="OBZ82760.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N0X5"/>
    <dbReference type="InParanoid" id="A0A1C7N0X5"/>
    <dbReference type="OrthoDB" id="2278014at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ82760.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="85" mass="9844" checksum="8F2D4A67385E35F3" modified="2016-11-30" version="1">MLSSIVSHSLYYNFHFALSVQSKGEKLQFQLKDLKVKGFQTIVSLMAKQYETLVRSNMVGIYESRTLCFYLELLPESNGEFYCSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N134</accession>
    <name>A0A1C7N134_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Ribosomal RNA small subunit methyltransferase H</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">rsmH</name>
        <name evidence="5" type="ORF">A0J61_09211</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the methyltransferase superfamily. RsmH family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000798">
        <property type="protein sequence ID" value="OBZ82741.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N134"/>
    <dbReference type="STRING" id="101091.A0A1C7N134"/>
    <dbReference type="InParanoid" id="A0A1C7N134"/>
    <dbReference type="OrthoDB" id="16290at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071424">
        <property type="term" value="F:rRNA (cytosine-N4-)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070475">
        <property type="term" value="P:rRNA base methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.170">
        <property type="entry name" value="Putative methyltransferase TM0872, insert domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01007">
        <property type="entry name" value="16SrRNA_methyltr_H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002903">
        <property type="entry name" value="RsmH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023397">
        <property type="entry name" value="SAM-dep_MeTrfase_MraW_recog"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00006">
        <property type="entry name" value="16S rRNA (cytosine(1402)-N(4))-methyltransferase RsmH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11265:SF0">
        <property type="entry name" value="12S RRNA N4-METHYLCYTIDINE METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11265">
        <property type="entry name" value="S-ADENOSYL-METHYLTRANSFERASE MRAW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01795">
        <property type="entry name" value="Methyltransf_5"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81799">
        <property type="entry name" value="Putative methyltransferase TM0872, insert domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="3 5" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010396"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OBZ82741.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="389" mass="44127" checksum="95514536D44468BD" modified="2016-11-30" version="1">MFSILRRTYSTVRLPYEKIHVPVLLPEVISHLSPKDGGVYCDMTFGDGGYTKALLDSCDCKVVAIDQDPTAYAKAKQLADLTDYKGRLFPVLGKFGSILDHLEQLDWQTPCFDGIMMDIGVSSGQIETPERGFSYKLDGPLDMRMFSRGRFGEAQDEDERRLLRKSISAYEIVNFFSREQIADIIYRYGGDRLSRKIAAAIVTARQTGPIETTASLATIIQTACPQPRWQRGHDDMVRNSAARTFQAFRIYINNELDELERALAATEYLLRPHGRLAVVTFHSLEDRIVKNFMQHCAGKRTLQDAEQNQFSLKRAATREYRKALKHGFSDINHKGSIPEQIQLTPSFEICTKHVIQPTEEELDLNARSRSAKLRVAERTMAPPLDPFNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-06-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N1J0</accession>
    <name>A0A1C7N1J0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_10717</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001338">
        <property type="protein sequence ID" value="OBZ81234.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N1J0"/>
    <dbReference type="InParanoid" id="A0A1C7N1J0"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ81234.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="71" mass="8344" checksum="932C50BBC2108AED" modified="2016-11-30" version="1">MDPSMTLQYWRAAVWDILADKAREDVQEAWKMYLSPLLCSEIIEHNQVSNDQPLTNLDEDVNLHSMARRKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N259</accession>
    <name>A0A1C7N259_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="1">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">CDC7</name>
        <name evidence="9" type="ORF">A0J61_09174</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="1"/>
    <dbReference type="EMBL" id="LUGH01000790">
        <property type="protein sequence ID" value="OBZ82776.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N259"/>
    <dbReference type="FunCoup" id="A0A1C7N259">
        <property type="interactions" value="549"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N259"/>
    <dbReference type="InParanoid" id="A0A1C7N259"/>
    <dbReference type="OrthoDB" id="10020333at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044773">
        <property type="term" value="P:mitotic DNA damage checkpoint signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd14019">
        <property type="entry name" value="STKc_Cdc7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44167:SF23">
        <property type="entry name" value="CDC7 KINASE, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44167">
        <property type="entry name" value="OVARIAN-SPECIFIC SERINE/THREONINE-PROTEIN KINASE LOK-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81995">
        <property type="entry name" value="beta-sandwich domain of Sec23/24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="9" id="KW-0132">Cell division</keyword>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="8">
        <location>
            <begin position="296"/>
            <end position="729"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="105"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="105"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="134"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="216"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="261"/>
            <end position="274"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OBZ82776.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="733" mass="83121" checksum="8524ACF7EBBA6ECA" modified="2016-11-30" version="1">MKSPIIKRKDNRGIPVVSPSRPSHSTSLIRKKTKAFDHQDDSVNDEVLLCRVRSTEHYATPDSPSQRQPIARMYHQSPHRLVSSPGIHSDSWQDASTEPIITKATCKSPNKLPSTIATQPPKKVVEGVIPSPPKSITRQDSSILQDQVLPSSQKRKVSDLEEEEEPRHRIKTLVETPNSLQKLKAPELEAKTCVSSTPESPLKKPPKKEPQEEEQQQQQQQQQPQQQQQQQQQQQPQQQPQQQPQQQQQQPQQQEGTTNDEAPHDTKQMTKEEEQARIAKEINHLMSTTKNLANYYKLVDKIGEGTFSTVYKAQDLRRELYNNEEWEPQLAAGEVKVMSEFVALKRIYHTSSPRRIANEVNILRKLKGSQCISPLITAFRQQDQVYVVMPYIQHDDFKKCFSEMGMDDIRYYLKSLFTALQQLHKHKILHRDVKPNNFLYHFRRRTGYLIDFGLAESENDIKALEQHIQKQTKILHHQHHASTTATPSIAANTNNTITNATATPSATPTSGTKATNNTMSKSALAALSNIEPRTTISATAVAQAAMAAATIQASESTPSPSNSLRGRAINSLGGRIPGYIKNDPRHNIRANRAGTRGFRAPEILMRVTKQTCAIDIWSVGVILLCFLTGRYPFFLANDEADSIIELGQIFGYKELEACAIKYERKFSTNTIIPNNRVPWTKVCESLNKERIKEWNPKDYENGIHLLDRCLDLDYTTRITAEEALNHPFLKDLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N2D5</accession>
    <name>A0A1C7N2D5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Mitochondrial import inner membrane translocase subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">TIM9_1</name>
        <name evidence="12" type="ORF">A0J61_09173</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space.</text>
    </comment>
    <comment type="subunit">
        <text evidence="10">Heterohexamer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Mitochondrion inner membrane</location>
            <topology evidence="10">Peripheral membrane protein</topology>
            <orientation evidence="10">Intermembrane side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="10">The twin CX3C motif contains 4 conserved Cys residues that form 2 disulfide bonds in the mitochondrial intermembrane space.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 10">Belongs to the small Tim family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000789">
        <property type="protein sequence ID" value="OBZ82779.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N2D5"/>
    <dbReference type="FunCoup" id="A0A1C7N2D5">
        <property type="interactions" value="530"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N2D5"/>
    <dbReference type="InParanoid" id="A0A1C7N2D5"/>
    <dbReference type="OrthoDB" id="1551503at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.810">
        <property type="entry name" value="Mitochondrial import inner membrane translocase subunit tim13 like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050673">
        <property type="entry name" value="Mito_inner_translocase_sub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004217">
        <property type="entry name" value="Tim10-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035427">
        <property type="entry name" value="Tim10-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13172">
        <property type="entry name" value="MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM9B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02953">
        <property type="entry name" value="zf-Tim10_DDP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144122">
        <property type="entry name" value="Tim10-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0143">Chaperone</keyword>
    <keyword evidence="9 10" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="4 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8 10" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="4 10" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="6 10" id="KW-0653">Protein transport</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 10" id="KW-0811">Translocation</keyword>
    <keyword evidence="2 10" id="KW-0813">Transport</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Tim10-like" evidence="11">
        <location>
            <begin position="16"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006720"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU367043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF02953"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="OBZ82779.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="98" mass="11335" checksum="CFFCDCF6215B0E8B" modified="2016-11-30" version="1">MDYSKYNYAEQAQINTMMEQRQMDDFVNMFTGLVDRCFKECANDFTTKAVTGKERTCVNKCAERFLKHSELVSKRFGELSQQQAAFIDVLNQSPTLSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-06-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N3Q6</accession>
    <name>A0A1C7N3Q6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_08665</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000689">
        <property type="protein sequence ID" value="OBZ83286.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N3Q6"/>
    <dbReference type="InParanoid" id="A0A1C7N3Q6"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ83286.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="79" mass="8753" checksum="070CC043E51A8027" modified="2016-11-30" version="1">MTLNQVKHAKIGLLASRSEQPIHPRIHCRMELVLTPVSQPTLEPNIPLSLEDYSGTTSSGNNNDSLVAERAMVLYHSFP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N4I7</accession>
    <name>A0A1C7N4I7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Chromatin structure-remodeling complex subunit RSC7</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">NPL6_1</name>
        <name evidence="13" type="ORF">A0J61_07940</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000569">
        <property type="protein sequence ID" value="OBZ84013.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N4I7"/>
    <dbReference type="STRING" id="101091.A0A1C7N4I7"/>
    <dbReference type="InParanoid" id="A0A1C7N4I7"/>
    <dbReference type="OrthoDB" id="787137at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013933">
        <property type="entry name" value="CRC_Rsc7/Swp82"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001965">
        <property type="entry name" value="Znf_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019787">
        <property type="entry name" value="Znf_PHD-finger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45888">
        <property type="entry name" value="HL01030P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45888:SF4">
        <property type="entry name" value="PHD FINGER PROTEIN 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08624">
        <property type="entry name" value="CRC_subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00628">
        <property type="entry name" value="PHD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00249">
        <property type="entry name" value="PHD"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50016">
        <property type="entry name" value="ZF_PHD_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="7" id="KW-0804">Transcription</keyword>
    <keyword evidence="6" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 9" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="PHD-type" evidence="11">
        <location>
            <begin position="587"/>
            <end position="655"/>
        </location>
    </feature>
    <feature type="domain" description="PHD-type" evidence="11">
        <location>
            <begin position="652"/>
            <end position="702"/>
        </location>
    </feature>
    <feature type="domain" description="PHD-type" evidence="11">
        <location>
            <begin position="747"/>
            <end position="811"/>
        </location>
    </feature>
    <feature type="domain" description="RING-type" evidence="12">
        <location>
            <begin position="750"/>
            <end position="809"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="46"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="246"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="472"/>
            <end position="516"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="OBZ84013.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="872" mass="98041" checksum="5C41E4AD99185069" modified="2016-11-30" version="1">MISFLHAKISTSQIKCIQLILLVYIQLDVLRTFKLPLLITMVRRKRGRPPMAAASPPPPPPSLRKSRSSDRSVQLASPEETQNTRPSRKRGRPSSHLSTPDDSADSIKRRREQSPSKSDDESDVDSAGEAKIDADGRLLGDREYKVPTFTLPDHGDQLLMLAMEPTKVLGFRDSYLLFHKHPQLKRVRISEEEKKMLVDMGLLVAWFKHRDVAVVTARSVFKCFGHKIVKRGKRIQDDYYEQDQPLRKNVEDEKDETELDTPSLLEDLQERDTTRKSLIGKTARSEGYISEAPMNQQTWMHHAALAARGFNAQLHERRIAKPVFYDIHSNVNQIPASLQSATCTFELISQEPTIEFKPHSNPHQLPLYRGIGGELLDYDVTKALDTLDQDKEIAQAVMKKPSTIKTLDNDEDSCFPLSLMEGQYQSNFPVHQARFNYTVPKIPDPCNLIDTAQSLAAQQYYLSLVYQSVNQFTPPQQPPQPQQLPTTSNNPTLPPVPENHQAKHVHLTRPPSQNFPYVPPPQQPMMRMPPTSTLPPPSNTVCGVPLGNNQLCQHPVNRTGERCSAHTAPKQMSEYTKGPPPSITYSDNKCADCHQLRAAETLFHSSEEHITDDFAVVKCAKCIRKYHPVCANLTTPRQVAAVESYPWSCPECKICCVCKSAGDESTLMICDGCDRGWHTGCCNPKVEKVPEGSWLCPLCANCHGCDEQGMAEESQYTHAIAPASDRYKYPIYLATYCNKCIQHFNQDRFCPVCLKTYAEEENDDEDNEMVACDTCDHWVHTRCDEILTPEKYQLLCDEEDAKYSCPMCEDRFKRLIDTSTADLALKGLSAPSGFCVGLLGGKVKTRGIVKYKDIKVGVPEINGTGIAEMPSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N4L9</accession>
    <name>A0A1C7N4L9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_07907</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000565">
        <property type="protein sequence ID" value="OBZ84043.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N4L9"/>
    <dbReference type="InParanoid" id="A0A1C7N4L9"/>
    <dbReference type="OrthoDB" id="10384600at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008889482" evidence="1">
        <location>
            <begin position="19"/>
            <end position="102"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ84043.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="102" mass="11327" checksum="C2ECEE34022FE699" modified="2016-11-30" version="1">MGFPITAFFLAASYFTSLLPLSKELMVTFPNKASEIKRGKLLRITWSTNATEGVVSVSLMSKSIHTANQKVLSLGQLNVHLEELEWIVPFDIPPGTQCKVDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N4U4</accession>
    <name>A0A1C7N4U4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">37S ribosomal protein mrp51, mitochondrial</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_07795</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000548">
        <property type="protein sequence ID" value="OBZ84155.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N4U4"/>
    <dbReference type="STRING" id="101091.A0A1C7N4U4"/>
    <dbReference type="InParanoid" id="A0A1C7N4U4"/>
    <dbReference type="OrthoDB" id="2735536at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016712">
        <property type="entry name" value="Rbsml_bS1m-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28058">
        <property type="entry name" value="37S RIBOSOMAL PROTEIN MRP51, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28058:SF1">
        <property type="entry name" value="SMALL RIBOSOMAL SUBUNIT PROTEIN BS1M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11709">
        <property type="entry name" value="Mit_ribos_Mrp51"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ84155.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="303" mass="34266" checksum="5D861520C5F2363F" modified="2016-11-30" version="1">MSNSFASLLRHSRLASYDRTLSQVYTTPLKHKKIGDWGLKRNLPTVIRTRYATIDSLDTAEHQTPWQSGNSQVLFVKRWKENFPHSKRPAPRSDSITYNVAKMTPADFRQFLKQCVHLAPEFQTLLAKKQIVPEQVFEFLKVAFTDSPSESIVGPTYSDIEVEPGYPVEGRILNHDGNGHAVGVGGVVAFLPRRSSVHLRQKGDRHVRTFFVESASIDEEGKPRVVLSATRPGSGSNLSLPLEFEALERDTSPMFTMTTENMFLTRKRSIEIAKDDDDRVQANPDHEKLMSRISSLITNTQQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N5W7</accession>
    <name>A0A1C7N5W7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">40S ribosomal protein S20</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">rps20_1</name>
        <name evidence="5" type="ORF">A0J61_07406</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uS10 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000498">
        <property type="protein sequence ID" value="OBZ84545.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N5W7"/>
    <dbReference type="FunCoup" id="A0A1C7N5W7">
        <property type="interactions" value="390"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N5W7"/>
    <dbReference type="InParanoid" id="A0A1C7N5W7"/>
    <dbReference type="OrthoDB" id="10248551at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015935">
        <property type="term" value="C:small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.600:FF:000002">
        <property type="entry name" value="40S ribosomal protein S20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.600">
        <property type="entry name" value="Ribosomal protein S10 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00508">
        <property type="entry name" value="Ribosomal_uS10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001848">
        <property type="entry name" value="Ribosomal_uS10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027486">
        <property type="entry name" value="Ribosomal_uS10_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036838">
        <property type="entry name" value="Ribosomal_uS10_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005729">
        <property type="entry name" value="Ribosomal_uS10_euk/arc"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01046">
        <property type="entry name" value="uS10_euk_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11700">
        <property type="entry name" value="30S RIBOSOMAL PROTEIN S10 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00338">
        <property type="entry name" value="Ribosomal_S10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00971">
        <property type="entry name" value="RIBOSOMALS10"/>
    </dbReference>
    <dbReference type="SMART" id="SM01403">
        <property type="entry name" value="Ribosomal_S10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54999">
        <property type="entry name" value="Ribosomal protein S10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 5" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Small ribosomal subunit protein uS10" evidence="4">
        <location>
            <begin position="25"/>
            <end position="119"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM01403"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OBZ84545.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="121" mass="13467" checksum="801C88C3E45270CF" modified="2016-11-30" version="1">MSAVAKSAAKPGLEEQVEAKIHRIRITLTSRNVKNLEKVSADLIQRAKDKQLKVKGPVRLPTKVLRITTRKSPCGNGSETFDKYEMKIHKRLIDLHSPSEIVKQITSISIEPGVEVEVTIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N5X2</accession>
    <name>A0A1C7N5X2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">COP9 signalosome complex subunit 5</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">CSN5</name>
        <name evidence="11" type="ORF">A0J61_07913</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="2">Component of the COP9 signalosome (CSN) complex.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase M67A family. CSN5 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000566">
        <property type="protein sequence ID" value="OBZ84036.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N5X2"/>
    <dbReference type="FunCoup" id="A0A1C7N5X2">
        <property type="interactions" value="832"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N5X2"/>
    <dbReference type="InParanoid" id="A0A1C7N5X2"/>
    <dbReference type="OrthoDB" id="605656at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008180">
        <property type="term" value="C:COP9 signalosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019784">
        <property type="term" value="F:deNEDDylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008237">
        <property type="term" value="F:metallopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000338">
        <property type="term" value="P:protein deneddylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd08069">
        <property type="entry name" value="MPN_RPN11_CSN5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.140.10:FF:000003">
        <property type="entry name" value="COP9 signalosome complex subunit 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.140.10">
        <property type="entry name" value="Cytidine Deaminase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040961">
        <property type="entry name" value="CSN5_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000555">
        <property type="entry name" value="JAMM/MPN+_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050242">
        <property type="entry name" value="JAMM_MPN+_peptidase_M67A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037518">
        <property type="entry name" value="MPN"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10410">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 3 -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18323">
        <property type="entry name" value="CSN5_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01398">
        <property type="entry name" value="JAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00232">
        <property type="entry name" value="JAB_MPN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102712">
        <property type="entry name" value="JAB1/MPN domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50249">
        <property type="entry name" value="MPN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="4" id="KW-0645">Protease</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0736">Signalosome</keyword>
    <keyword evidence="8" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="MPN" evidence="10">
        <location>
            <begin position="53"/>
            <end position="190"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00014880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="OBZ84036.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="334" mass="37946" checksum="22D5DB3B802F1D9D" modified="2016-11-30" version="1">MDAATAQKNWELENNITAVDPAQDLIYYYDAAQDKENVAQKPWKNDPNYFKHVKVSAIALIKMVMHARSGGNIEVMGLMQGKIQGDTMYVMDSFALPVEGTETRVNAQNEAYEYMVSYIEKSKEVGRLENVLGWYHSHPGYGCWLSGIDVSTQMLNQQYQEPFVAVVIDPNRTMSAGKVEIGAFRTYPAGYKAPDEGPSEYQTIPLNKIEDFGVHAKSYYSLEVSHFKSTLDTQLLEVLWNKYWVNTLSQSSLLTNRDYSTRQMTDLAQKLKKTNVNMLSRMGGYYGDRKKNDESQLSKVTRDSSKISVEAVHGLLSQVLKDQVFNQSRNKDHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N6Q0</accession>
    <name>A0A1C7N6Q0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Chitin biosynthesis protein CHS5</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">CHS5_1</name>
        <name evidence="3" type="ORF">A0J61_07667</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000531">
        <property type="protein sequence ID" value="OBZ84279.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N6Q0"/>
    <dbReference type="STRING" id="101091.A0A1C7N6Q0"/>
    <dbReference type="InParanoid" id="A0A1C7N6Q0"/>
    <dbReference type="OrthoDB" id="245697at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034044">
        <property type="term" value="C:exomer complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005802">
        <property type="term" value="C:trans-Golgi network"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000747">
        <property type="term" value="P:conjugation with cellular fusion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006893">
        <property type="term" value="P:Golgi to plasma membrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd17742">
        <property type="entry name" value="BRCT_CHS5_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd13945">
        <property type="entry name" value="Chs5_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00063">
        <property type="entry name" value="FN3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.20.120.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10190">
        <property type="entry name" value="BRCT domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001357">
        <property type="entry name" value="BRCT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036420">
        <property type="entry name" value="BRCT_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031673">
        <property type="entry name" value="Chs5_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052827">
        <property type="entry name" value="CHS_Export/Cell_Fusion_Reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031669">
        <property type="entry name" value="Fn3_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003961">
        <property type="entry name" value="FN3_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036116">
        <property type="entry name" value="FN3_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47351">
        <property type="entry name" value="CHITIN BIOSYNTHESIS PROTEIN CHS5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47351:SF1">
        <property type="entry name" value="CHITIN BIOSYNTHESIS PROTEIN CHS5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16892">
        <property type="entry name" value="CHS5_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16893">
        <property type="entry name" value="fn3_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12738">
        <property type="entry name" value="PTCB-BRCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00292">
        <property type="entry name" value="BRCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52113">
        <property type="entry name" value="BRCT domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49265">
        <property type="entry name" value="Fibronectin type III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50172">
        <property type="entry name" value="BRCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50853">
        <property type="entry name" value="FN3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fibronectin type-III" evidence="2">
        <location>
            <begin position="76"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="domain" description="BRCT" evidence="1">
        <location>
            <begin position="163"/>
            <end position="253"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ84279.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="260" mass="29236" checksum="ACD2E2367DD370E2" modified="2016-11-30" version="1">MTSVQFTVGKLDAGMAILLTEDHHLIEFPSLLLPKGVTSGSIVNIAVSRNNSEEEKKMNEFWELQNNILTMFGNEEPEPPVVRVKNITQTSLILEWDPLSLHKAKLRSLDVYKNGEKLAQHVPSDTNFIKLSGLAVDQEFQFHIVIKTTAGEYKSNTIEARTHKMENLTGIRVAFGLFEEPEPALTELKDLLNRIGASYTDEVNAETTHLLAQLPGGANYDRAVHHSIPIVKPEWLVQCDRNKKIQPALPYYIINVPNTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N700</accession>
    <name>A0A1C7N700_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Thc1 RRM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_07027</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000454">
        <property type="protein sequence ID" value="OBZ84925.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N700"/>
    <dbReference type="InParanoid" id="A0A1C7N700"/>
    <dbReference type="OrthoDB" id="5418203at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039884">
        <property type="entry name" value="R3HC1/R3HCL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053800">
        <property type="entry name" value="Thc1_RRM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21678:SF0">
        <property type="entry name" value="C3H1-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21678">
        <property type="entry name" value="GROWTH INHIBITION AND DIFFERENTIATION RELATED PROTEIN 88"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22877">
        <property type="entry name" value="RRM_Thc1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thc1 RRM" evidence="2">
        <location>
            <begin position="64"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="137"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="156"/>
            <end position="170"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF22877"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ84925.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="185" mass="21731" checksum="5608AB4FB91FDD70" modified="2016-11-30" version="1">MGGDYDYNEQQEDWENILRQYDRYSSNDDDRRRSKRASRIMDAYQDTPVEIPVVDEPTTVLDCYDFPPAFKTHHLHDIFRSYESSRGGYRIKWLSDTRALIIFDHPSTAKKAYIDNVAHALAKIRPYEGPLDFLKENQAPQTQQRRPMSMDNKRQSFNGYSNGRNSNRNSMRIDESDIKRLSVAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N752</accession>
    <name>A0A1C7N752_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Short-chain dehydrogenase TIC 32, chloroplastic</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">TIC32</name>
        <name evidence="3" type="ORF">A0J61_07505</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000509">
        <property type="protein sequence ID" value="OBZ84446.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N752"/>
    <dbReference type="STRING" id="101091.A0A1C7N752"/>
    <dbReference type="InParanoid" id="A0A1C7N752"/>
    <dbReference type="OrthoDB" id="191139at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05327">
        <property type="entry name" value="retinol-DH_like_SDR_c_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24320:SF148">
        <property type="entry name" value="NAD(P)-BINDING ROSSMANN-FOLD SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24320">
        <property type="entry name" value="RETINOL DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ84446.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="315" mass="34716" checksum="9297178AD904219A" modified="2016-11-30" version="1">MNQITSRTTAEQIAQFYNIDLKGKVAIVTGSNSGTGLETARVFSKFGAKVIIPCRTLEKSNGAIDHIKKTVPEADLIPMQLDLSDLSSIKRFATDFLALDIPLHLLINNAGIMACPKQFTKDGFESQFGVNHLGHFYLTSLLLDKLKASAPARIVNLTSSGSFFFESKEGIDFDNLYAEKHYSPFMVYGQSKLANILHAKELQRRLEGVDVTVTSVHPGAVATNLGRSLGPSALFDMAWNVKKTTSFLIDLVNIKYPPEGASTTVYCAVSPDVVKGEYYGDNTIETRFRSQHVDNKALAEKLWKVSEEMIASKLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N7D6</accession>
    <name>A0A1C7N7D6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Myb-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">A0J61_07067</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000459">
        <property type="protein sequence ID" value="OBZ84878.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N7D6"/>
    <dbReference type="STRING" id="101091.A0A1C7N7D6"/>
    <dbReference type="InParanoid" id="A0A1C7N7D6"/>
    <dbReference type="OrthoDB" id="39591at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000976">
        <property type="term" value="F:transcription cis-regulatory region binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051651">
        <property type="entry name" value="DMTF1_DNA-bind_reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001005">
        <property type="entry name" value="SANT/Myb"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46380">
        <property type="entry name" value="CYCLIN-D-BINDING MYB-LIKE TRANSCRIPTION FACTOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46380:SF2">
        <property type="entry name" value="CYCLIN-D-BINDING MYB-LIKE TRANSCRIPTION FACTOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00717">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Myb-like" evidence="5">
        <location>
            <begin position="273"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="domain" description="Myb-like" evidence="5">
        <location>
            <begin position="323"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="22"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="22"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="34"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="74"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="104"/>
            <end position="119"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00717"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OBZ84878.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="455" mass="53088" checksum="8EC79AA326A07BE5" modified="2016-11-30" version="1">MVEKKARRRKMRPNNVIAIERANTERIYEEKKKQICQHKLPPKKKKQQMAVESASDSDETDHETEKNRGASEADSSEADNNEADTQADNDTKNKKRVREDSEEEGQKKQKITDSAKKSILDANRISFRRRIDADPAKPVSVNYKNKLLDTFVPDVKADDFISASDSEEDSGDDYESKDYPAWQRTLGWNPEPDTAPWPKQRKLGYSDKLKLEKRIKKVCKRENMTFAEAREIFSSSNRKPHIRFFQKIAKVFPNISLHMLAKVCKETYHEKRNNSPWQPEEIELLQELLKVHGPNTSILCQHLNRSPKNITDCLFSLRNVSKNNKRWSKEEDEKLAKIIAEGKQKTGERPTFPSIVPMFNGERTQKQIYQRYHHIQHRIMPDGTLLPDRKPTAQEELEYLEKLMEQVREHDLVEESQLDLSKEKGFVKRSFYLRSRAQIPGFETMKVKGKDHIGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N7K0</accession>
    <name>A0A1C7N7K0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">SAM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">A0J61_07348</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000490">
        <property type="protein sequence ID" value="OBZ84599.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N7K0"/>
    <dbReference type="InParanoid" id="A0A1C7N7K0"/>
    <dbReference type="OrthoDB" id="2155283at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000932">
        <property type="term" value="C:P-body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000289">
        <property type="term" value="P:nuclear-transcribed mRNA poly(A) tail shortening"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.50">
        <property type="entry name" value="Transcription Factor, Ets-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001660">
        <property type="entry name" value="SAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013761">
        <property type="entry name" value="SAM/pointed_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050897">
        <property type="entry name" value="SMAUG/VTS1_RNA-bind"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057327">
        <property type="entry name" value="Vts1_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12515:SF5">
        <property type="entry name" value="PROTEIN SMAUG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12515">
        <property type="entry name" value="STERILE ALPHA MOTIF DOMAIN CONTAINING PROTEIN 4-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07647">
        <property type="entry name" value="SAM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25479">
        <property type="entry name" value="Vts1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00454">
        <property type="entry name" value="SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47769">
        <property type="entry name" value="SAM/Pointed domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50105">
        <property type="entry name" value="SAM_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="SAM" evidence="5">
        <location>
            <begin position="385"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="163"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="283"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="335"/>
            <end position="362"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50105"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OBZ84599.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="451" mass="51562" checksum="BC7C7E38410A4E56" modified="2016-11-30" version="1">MHPSDFSSSKQGRPISSYLDCNDSVDGNALGTWYEDLEEYEDNLEKMATANLDQSFQDELQHVNQWFGFLSDAEKTATIYALLQHSSQVQIKFFIRMLQEMRKSNPLNREKASERASTLMNLSNRRLSSINQQQNRNASSRHSFALGDTQELSRIFDSSNKKWLDSEEPHHPSPPQPRTTISVPRASSRLRPRSVIELNHAPSSFSNSWLRQPNVFNSAGVTENYRPIERPRSADITSWHLPSSTNTSATWQTLSSPHDINAQSHWKNNNNWIHVQQPQPTTSSGLFHYFDKPKSSSSPTTTSAGVRFNDEYNQFLGPSKPNLDHKKNHGYGSDPGNNSSAKYGSRLSSVQNTSNHHQSLSHPKTRSTHLEPSAKEEAVDMELLEDVTAWFRSMRLHKYNTIFEKMRWQDIVKLNDQELQDIGVAALGARRKMLKVFENIQEHCKSHHVDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N7L7</accession>
    <name>A0A1C7N7L7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="17">L-lactate dehydrogenase (cytochrome)</fullName>
            <ecNumber evidence="16">1.1.2.3</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="19">Cytochrome b2</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="18">Flavocytochrome b2</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="20">L-lactate ferricytochrome c oxidoreductase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="25" type="primary">CYB2</name>
        <name evidence="25" type="ORF">A0J61_06819</name>
    </gene>
    <organism evidence="25 26">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="25 26" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="25 26">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>(S)-lactate + 2 Fe(III)-[cytochrome c] = 2 Fe(II)-[cytochrome c] + pyruvate + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:19909"/>
            <dbReference type="Rhea" id="RHEA-COMP:10350"/>
            <dbReference type="Rhea" id="RHEA-COMP:14399"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16651"/>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
            <dbReference type="ChEBI" id="CHEBI:29034"/>
            <dbReference type="EC" id="1.1.2.3"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="13">
            <dbReference type="Rhea" id="RHEA:19910"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homotetramer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion intermembrane space</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="21">Belongs to the cytochrome b5 family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="14">In the C-terminal section; belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="15">In the N-terminal section; belongs to the cytochrome b5 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="25">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.2.3" evidence="16"/>
    <dbReference type="EMBL" id="LUGH01000430">
        <property type="protein sequence ID" value="OBZ85130.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N7L7"/>
    <dbReference type="FunCoup" id="A0A1C7N7L7">
        <property type="interactions" value="121"/>
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    <dbReference type="STRING" id="101091.A0A1C7N7L7"/>
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        <property type="component" value="Unassembled WGS sequence"/>
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        <property type="project" value="UniProtKB-SubCell"/>
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    <dbReference type="GO" id="GO:0004460">
        <property type="term" value="F:L-lactate dehydrogenase (cytochrome) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006089">
        <property type="term" value="P:lactate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
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        <property type="entry name" value="Cytochrome b2, mitochondrial, putative"/>
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    </dbReference>
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    <keyword evidence="9" id="KW-0809">Transit peptide</keyword>
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        <location>
            <begin position="1"/>
            <end position="78"/>
        </location>
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            <begin position="104"/>
            <end position="466"/>
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            <begin position="272"/>
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    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="495" mass="55472" checksum="A4E1ABB7F97CD529" modified="2016-11-30" version="1">MTILSPKEVAKHNKRDDIWVIIHGKVYDLTNFLPEHPGGQKIILKYAGKDATSAFEPIHPPDIIQRFLSPEVCKGSIDAEALAKEPKEESKEEKRVRLARENMPRLEEMYNAFDFETVAKSVLKSDAWAYYSSGADDEISMRENHNAFHRIWLRPRVMVNVKNVDPSTVMLGSRTAMPVYITATALGKLGHPQGEVVLTKAAHKRNVIQMIPTLASCSFDEIVDAAGPDQTQWLQLYVNGNREVSEKFVRHAEKRGMKGLFITADAPQLGHREKDMRQKYSQEEPEEFSRSGSEINRDQGAARAISSFIDPSLCWDDIAWFKSITNMPILIKGIQTPEDAVLAAKHGCQGIVLSNHGGRQLDFAPSSIEILAETMDALKKENLDKNFEVYIDGGIRRGTDIFKAIALGAKGVGIGRPCLYAMSTYGIEGVERLLELLQDEFEMVMRLMGVTSIAEIKPSMVDIRNIKDHFVSNPIDYLASSAYEKMQPRGHLSKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N7U1</accession>
    <name>A0A1C7N7U1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">A0J61_07262</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000481">
        <property type="protein sequence ID" value="OBZ84686.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
    <dbReference type="InterPro" id="IPR028143">
        <property type="entry name" value="Get2/sif1"/>
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    <dbReference type="PANTHER" id="PTHR28263">
        <property type="entry name" value="GOLGI TO ER TRAFFIC PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28263:SF1">
        <property type="entry name" value="GOLGI TO ER TRAFFIC PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="135"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="173"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="239"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="42"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="7"/>
            <end position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
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            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OBZ84686.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="262" mass="30682" checksum="CF34A408D13270D2" modified="2016-11-30" version="1">MDPKEHERQEKRRLRRQERILASAESRLHKITATIFREWTPSPSNSDALSLAEHYPASNDTRRRKYERSITPSPSSSAKHRPVVQQLIEEEEQQQQQKVQLNGWLGDKVPHLLLAYMLRRTSIRPKRSSDPANRYWHLLHFLSMAWLGFLAVYEQASIHGWTHVSSLIKTHPTHPIVQFPVFIYFVILEFLLRFGRTIYQPNDKSPDQAAFINMVSQLPPPLQQPVYWIQTYGLLIHSLFKDVCIVVFMIGFTGLFLLVFKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N7V9</accession>
    <name>A0A1C7N7V9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Allergen Asp f 7</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">A0J61_06892</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000438">
        <property type="protein sequence ID" value="OBZ85058.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N7V9"/>
    <dbReference type="STRING" id="101091.A0A1C7N7V9"/>
    <dbReference type="InParanoid" id="A0A1C7N7V9"/>
    <dbReference type="OrthoDB" id="406505at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd22191">
        <property type="entry name" value="DPBB_RlpA_EXP_N-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.40.10">
        <property type="entry name" value="RlpA-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051477">
        <property type="entry name" value="Expansin_CellWall"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009009">
        <property type="entry name" value="RlpA-like_DPBB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036908">
        <property type="entry name" value="RlpA-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31836">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31836:SF21">
        <property type="entry name" value="EXPANSIN-LIKE PROTEIN 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03330">
        <property type="entry name" value="DPBB_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50685">
        <property type="entry name" value="Barwin-like endoglucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008889536" evidence="3">
        <location>
            <begin position="21"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="domain" description="RlpA-like protein double-psi beta-barrel" evidence="4">
        <location>
            <begin position="282"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="48"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="132"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="49"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="141"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="183"/>
            <end position="207"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF03330"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OBZ85058.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="339" mass="38425" checksum="9F692DDBCD0086A3" modified="2016-11-30" version="1">MKGFILTAILILSLACFSKADLPNDMFYHHHPDLIDVDLDKHFAKPNNRMAQANDNPSQLDSHSSGQTDSGFSQHNREPAQPEQYYTYDRQNDNYENRYYSPPEPAQRNGYNEYSDARNNYFNTFARNSVQNNGYDPYYRNYQSNNQGSNRYNDYSSPPRPVNKIVYNDDGSINWEKSKSDSKNMNNRNQAQQTNGKPFQGHNSQYSNDKEMVPMRMDPSNSAREIRLAGALPEDGYYRGVGTYYDLETRVSSCGKQNQNSELVVALNSQQMGKEAGRNNSNCGKQIEVTGPSGKSVRVTVVDECKTCPKGGLDLSPAAFEEIGDFSHGSIPIKWKFTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N841</accession>
    <name>A0A1C7N841_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">60S acidic ribosomal protein P2-beta</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">rpp202_1</name>
        <name evidence="5" type="ORF">A0J61_07129</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the eukaryotic ribosomal protein P1/P2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000465">
        <property type="protein sequence ID" value="OBZ84816.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N841"/>
    <dbReference type="FunCoup" id="A0A1C7N841">
        <property type="interactions" value="436"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N841"/>
    <dbReference type="InParanoid" id="A0A1C7N841"/>
    <dbReference type="OrthoDB" id="1227494at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022625">
        <property type="term" value="C:cytosolic large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002182">
        <property type="term" value="P:cytoplasmic translational elongation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05833">
        <property type="entry name" value="Ribosomal_P2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.1410:FF:000002">
        <property type="entry name" value="60S acidic ribosomal protein P2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.1410">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01478">
        <property type="entry name" value="Ribosomal_L12_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038716">
        <property type="entry name" value="P1/P2_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027534">
        <property type="entry name" value="Ribosomal_P1/P2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044076">
        <property type="entry name" value="Ribosomal_P2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21141">
        <property type="entry name" value="60S ACIDIC RIBOSOMAL PROTEIN FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21141:SF5">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN P2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00428">
        <property type="entry name" value="Ribosomal_60s"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 5" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="83"/>
            <end position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005436"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OBZ84816.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="108" mass="10737" checksum="A96FA0078D32CF72" modified="2016-11-30" version="1">MKYLASYLLLVAGGKTSPSAADLKSLLATVGAEADEERVNSLISALEGKNTEELIAEGLEKMSSVPTGGAVAAAGASGAAAASDAPAAEAAAEEKEESDDDMGFGLFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N883</accession>
    <name>A0A1C7N883_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Translationally-controlled tumor protein homolog</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">TMA19</name>
        <name evidence="4" type="ORF">A0J61_06643</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the TCTP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000411">
        <property type="protein sequence ID" value="OBZ85313.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N883"/>
    <dbReference type="FunCoup" id="A0A1C7N883">
        <property type="interactions" value="668"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N883"/>
    <dbReference type="InParanoid" id="A0A1C7N883"/>
    <dbReference type="OrthoDB" id="10248936at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="2.170.150.10:FF:000002">
        <property type="entry name" value="Translationally-controlled tumor protein homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.150.10">
        <property type="entry name" value="Metal Binding Protein, Guanine Nucleotide Exchange Factor, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011057">
        <property type="entry name" value="Mss4-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011323">
        <property type="entry name" value="Mss4/transl-control_tumour"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034737">
        <property type="entry name" value="TCTP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018103">
        <property type="entry name" value="Translation_control_tumour_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018105">
        <property type="entry name" value="Translational_control_tumour_p"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11991">
        <property type="entry name" value="TRANSLATIONALLY CONTROLLED TUMOR PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11991:SF0">
        <property type="entry name" value="TRANSLATIONALLY-CONTROLLED TUMOR PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00838">
        <property type="entry name" value="TCTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01653">
        <property type="entry name" value="TCTPROTEIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51316">
        <property type="entry name" value="Mss4-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01002">
        <property type="entry name" value="TCTP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01003">
        <property type="entry name" value="TCTP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51797">
        <property type="entry name" value="TCTP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TCTP" evidence="3">
        <location>
            <begin position="1"/>
            <end position="165"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00014759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51797"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OBZ85313.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="165" mass="18548" checksum="E3091B0A5E2A5E2F" modified="2016-11-30" version="1">MLLYEDILTGDELFSDAFPLKLVDDVAYEVDCKMITISEGNIDIGANPSAEGEDDEGVDSTSETVNNVVHSHRLVQTSFDKKSYMVYIKGYMKAVKAKLPEERVPTFEKNVAALVKKILGNFKDYEFYTGESMDPDGMVALLNYREDGVTPFFTFFKDGVKEVKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N8E9</accession>
    <name>A0A1C7N8E9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_06587</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000404">
        <property type="protein sequence ID" value="OBZ85363.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N8E9"/>
    <dbReference type="InParanoid" id="A0A1C7N8E9"/>
    <dbReference type="OrthoDB" id="2281274at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ85363.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="111" mass="13222" checksum="1ACF97BF12DE1997" modified="2016-11-30" version="1">MDEKRLGNTADNVPIAFILLERNPSPPKYEHVIENNPPPPSYMHSAVRLQYHNQPYITDVEQHEFRRQHDMRCASAAEDIQNDTFSTIARLPFRKRLLLWGYWFRLLLFQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N927</accession>
    <name>A0A1C7N927_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Importin subunit beta-3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">sal3</name>
        <name evidence="10" type="ORF">A0J61_06814</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000429">
        <property type="protein sequence ID" value="OBZ85139.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N927"/>
    <dbReference type="FunCoup" id="A0A1C7N927">
        <property type="interactions" value="678"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N927"/>
    <dbReference type="InParanoid" id="A0A1C7N927"/>
    <dbReference type="OrthoDB" id="543373at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034399">
        <property type="term" value="C:nuclear periphery"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061608">
        <property type="term" value="F:nuclear import signal receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008139">
        <property type="term" value="F:nuclear localization sequence binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031267">
        <property type="term" value="F:small GTPase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006406">
        <property type="term" value="P:mRNA export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006606">
        <property type="term" value="P:protein import into nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007088">
        <property type="term" value="P:regulation of mitotic nuclear division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0060188">
        <property type="term" value="P:regulation of protein desumoylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058584">
        <property type="entry name" value="IMB1_TNPO1-like_TPR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001494">
        <property type="entry name" value="Importin-beta_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040122">
        <property type="entry name" value="Importin_beta"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041653">
        <property type="entry name" value="Importin_rep_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041389">
        <property type="entry name" value="Importin_rep_6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034085">
        <property type="entry name" value="TOG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057672">
        <property type="entry name" value="TPR_IPO4/5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10527">
        <property type="entry name" value="IMPORTIN BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13513">
        <property type="entry name" value="HEAT_EZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18808">
        <property type="entry name" value="Importin_rep_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18829">
        <property type="entry name" value="Importin_rep_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25574">
        <property type="entry name" value="TPR_IMB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25780">
        <property type="entry name" value="TPR_IPO5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01349">
        <property type="entry name" value="TOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50166">
        <property type="entry name" value="IMPORTIN_B_NT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Importin N-terminal" evidence="9">
        <location>
            <begin position="32"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="815"/>
            <end position="840"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="823"/>
            <end position="840"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50166"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OBZ85139.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="1098" mass="121692" checksum="BB0C1A70A3212B0E" modified="2016-11-30" version="1">MAQTPVSAEVLQQLAPVLTSLLSTDNNQRAAAEAQLNDQWVAQQPDLLLLGLAQFVATNTEVQLRSHCSVLLRRLAYKQFTTSTNPDTRLWDMVQDSTRQGVKELLLVALANESDQGTRHKVSDTIAEVARSDLSEGNKWDTLLKALFECSQSPNAALRESAFRIFASVPELIAGQHTDALKNVFLTSLTDAESQAVRLEAMKAAAAYIGQADEQTQKALGVLMPHMLEPLSPVIASRDDQTLVDGLVVLIELGDNAPKLFRPVFPNVLTVMVSVAKDKSFDDRTRQTALELLLTLSEAAPPMARKLPNFATEVIPVAMEMITDMEDDESWYTTDELDEDDNEENYVMGESTLDRVARTLGGKAVVPVAFQFIPQMLQSGEWQQRRAALMAISSIAEGSIKIMKPELSNIMNMILPSFKDAHPRVRYAACNAVGQLSTDFAPYIQKHFHEIVISALLPVMEDAQPRVQAHAAAAMVNFCEEANKKILDPYLDAIFERLLILLKTSKTYVQEQAITTIATVADCAEDKFNKYHSVIMPLLLDILRQASDKQYRLLRSRAIECASLIGLAIGKEAFAPYTANFINILAEIQQSVTESDDIQTTYLLAAWARMCKMMGQDFLPYLPNIMPPLLQSAKLTPEFTFVDPEDDDVESKYPTEDGWEFVGINGQQIGIKTSVLEEKHTAIEMLVSYARDLGAGFLPYVGQVLEIALPLLKFYFHDGVRHAAAALIPLLLKDAKDANVAPAELANMWNTIFEKLAKIMTIEDDVTFLAQTYATFSECLDVLTENCLQPAQIESFMKGVDEQLKKFLERLTEREQEKQSGEFDAEDEEQMGDDEATEEDALSELARAIQSLFKALGPNFLPYFDQMLPLVVQFLAHPNNAARQWAICVFDDLVEFTGPASFNYSNYFLQGMIAGVSDKAMEVRQAAAYGVGVMGQFGGPQYADACAASLEHLFGIINAPDAREDGIVFVTENAISAIAKICKFNSSKFQLEPVLSAWLSTLPIVNDDQEAPIVYTYLLDLLEANHPSILGPNNSNLPHLVKIFTEVLASDILPVELAARMVNNLKIILGGLDENTRNQLWNAISVETRTVLQKKGYV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N9B7</accession>
    <name>A0A1C7N9B7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 16 17">Phosphatidate cytidylyltransferase</fullName>
            <ecNumber evidence="6 16 17">2.7.7.41</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">A0J61_06261</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18 19">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 16 17">
            <text>a 1,2-diacyl-sn-glycero-3-phosphate + CTP + H(+) = a CDP-1,2-diacyl-sn-glycerol + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:16229"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:37563"/>
            <dbReference type="ChEBI" id="CHEBI:58332"/>
            <dbReference type="ChEBI" id="CHEBI:58608"/>
            <dbReference type="EC" id="2.7.7.41"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="4">Lipid metabolism.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3 16 17">Phospholipid metabolism; CDP-diacylglycerol biosynthesis; CDP-diacylglycerol from sn-glycerol 3-phosphate: step 3/3.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5 16 17">Belongs to the CDS family.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.41" evidence="6 16 17"/>
    <dbReference type="EMBL" id="LUGH01000370">
        <property type="protein sequence ID" value="OBZ85690.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N9B7"/>
    <dbReference type="FunCoup" id="A0A1C7N9B7">
        <property type="interactions" value="544"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N9B7"/>
    <dbReference type="InParanoid" id="A0A1C7N9B7"/>
    <dbReference type="OrthoDB" id="10260889at2759"/>
    <dbReference type="UniPathway" id="UPA00557">
        <property type="reaction ID" value="UER00614"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004605">
        <property type="term" value="F:phosphatidate cytidylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016024">
        <property type="term" value="P:CDP-diacylglycerol biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000374">
        <property type="entry name" value="PC_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016720">
        <property type="entry name" value="PC_Trfase_euk"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13773">
        <property type="entry name" value="PHOSPHATIDATE CYTIDYLYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13773:SF8">
        <property type="entry name" value="PHOSPHATIDATE CYTIDYLYLTRANSFERASE, PHOTORECEPTOR-SPECIFIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01148">
        <property type="entry name" value="CTP_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF018269">
        <property type="entry name" value="PC_trans_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01315">
        <property type="entry name" value="CDS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 16" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="12 16" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="13 16" id="KW-0472">Membrane</keyword>
    <keyword evidence="10 16 17" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="14 16" id="KW-0594">Phospholipid biosynthesis</keyword>
    <keyword evidence="15 16" id="KW-1208">Phospholipid metabolism</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 16 17" id="KW-0808">Transferase</keyword>
    <keyword evidence="9 16 17" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="11 16" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="39"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="62"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="100"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="139"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="176"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="200"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="238"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="335"/>
            <end position="355"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001698"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00010185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00012487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PIRNR" id="PIRNR018269"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="RuleBase" id="RU003938"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="OBZ85690.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="463" mass="53120" checksum="A0B2396F8A073BAE" modified="2016-11-30" version="1">MSNSKKKSAKPAVETPKQAQEEKVTLLAAESSKKKWQNWWLRTITTFMMIGTFFLILASGHIWVILMVIAISTVVYNEVLQIAQGPAKDSNFKWFKTMSWYFLVTTTYFLYGESIIYYFQHVVLVDRVLLPFATHHRFISFILYVIANADFDCTPGFVFFVMNLKKGEYKRQFRQFGWMHMALLLVVFQSHFIVNNILEGLIWFFIPTSLVICNDIFAYICGFFWGRHQLIQLSPKKTIEGFVGAWICTLIFGFLWSTLLMRFDYMICPVKQADADILLKDLSMSAWSQIGCDPVNPVFTAVPWKLPDLWITIIKTLFHKDITKVWIAPVQLHTLVWACFASLIAPFGGFFASGVKRAFNVKDFGQSIPGHGGMTDRMDCQFLMGFFAYIYYQSFIKTYNLNVGTILATIINNLSLNDQLELLERILTYFVNQGVLDPTVLQKCGASALTDTARQILETPPSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N9K1</accession>
    <name>A0A1C7N9K1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">WD repeat-containing protein 91</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">wdr91_0</name>
        <name evidence="2" type="ORF">A0J61_07928</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000568">
        <property type="protein sequence ID" value="OBZ84024.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N9K1"/>
    <dbReference type="STRING" id="101091.A0A1C7N9K1"/>
    <dbReference type="InParanoid" id="A0A1C7N9K1"/>
    <dbReference type="OrthoDB" id="193023at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031901">
        <property type="term" value="C:early endosome membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031902">
        <property type="term" value="C:late endosome membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0141039">
        <property type="term" value="F:phosphatidylinositol 3-kinase inhibitor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045022">
        <property type="term" value="P:early endosome to late endosome transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051898">
        <property type="term" value="P:negative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039724">
        <property type="entry name" value="WDR91"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13083">
        <property type="entry name" value="WD REPEAT-CONTAINING PROTEIN 91"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13083:SF3">
        <property type="entry name" value="WD REPEAT-CONTAINING PROTEIN 91"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="78"/>
            <end position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ84024.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="202" mass="21885" checksum="8E2091AA87717B29" modified="2016-11-30" version="1">MVVVGDTTGYMRLFASLDIRSMKPIIEWKGNPSCTAQFSFDETSICSVDLDGQLSQWSIHKPGTCIFSSPLEGFPTPSTAYASQSKPSANTSFTKPSSIDQYGKKARSIDNQVTRSLLSIHPRPQMAAFSTDTDYVLCASHAQDETFGSIYRVSETDSSSVLQLGNQPIYQPITTVGWTSTSNACLVGSMDGSIKVSTLIKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N9N0</accession>
    <name>A0A1C7N9N0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Required for respiratory growth protein 7, mitochondrial</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_06301</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000374">
        <property type="protein sequence ID" value="OBZ85648.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N9N0"/>
    <dbReference type="InParanoid" id="A0A1C7N9N0"/>
    <dbReference type="OrthoDB" id="20734at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1350.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018828">
        <property type="entry name" value="RRG7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011856">
        <property type="entry name" value="tRNA_endonuc-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28133">
        <property type="entry name" value="REQUIRED FOR RESPIRATORY GROWTH PROTEIN 7, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28133:SF1">
        <property type="entry name" value="REQUIRED FOR RESPIRATORY GROWTH PROTEIN 7, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10356">
        <property type="entry name" value="RRG7"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ85648.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="187" mass="20698" checksum="41B881ECB1098D06" modified="2016-11-30" version="1">MLVRYSLRKNITSIPNTTKLSNFLKQTNKDTTSNVYRGTLFELQTLESLSSMTGMSLDHCGGKGDGGIDLRGQWFNQINVLVQCKNTKQGCTPDHIRELMGTVLSTTTKKKKVLGILSTVSHKQFTRDVLSLFNASPVPLGLAMVEETTLKSLMFNKKAQSILKGLTITTQYDAQGNETLFVEMSAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N9U2</accession>
    <name>A0A1C7N9U2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Protein CSN12</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">CSN12</name>
        <name evidence="4" type="ORF">A0J61_06572</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the CSN12 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000403">
        <property type="protein sequence ID" value="OBZ85376.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N9U2"/>
    <dbReference type="FunCoup" id="A0A1C7N9U2">
        <property type="interactions" value="606"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N9U2"/>
    <dbReference type="InParanoid" id="A0A1C7N9U2"/>
    <dbReference type="OrthoDB" id="10252687at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005680">
        <property type="term" value="C:anaphase-promoting complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070390">
        <property type="term" value="C:transcription export complex 2"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003690">
        <property type="term" value="F:double-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031145">
        <property type="term" value="P:anaphase-promoting complex-dependent catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016973">
        <property type="term" value="P:poly(A)+ mRNA export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000973">
        <property type="term" value="P:post-transcriptional tethering of RNA polymerase II gene DNA at nuclear periphery"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006368">
        <property type="term" value="P:transcription elongation by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018860">
        <property type="entry name" value="APC_suCDC26"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045114">
        <property type="entry name" value="Csn12-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000717">
        <property type="entry name" value="PCI_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12732:SF0">
        <property type="entry name" value="PCI DOMAIN-CONTAINING PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12732">
        <property type="entry name" value="UNCHARACTERIZED PROTEASOME COMPONENT REGION PCI-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10471">
        <property type="entry name" value="ANAPC_CDC26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01399">
        <property type="entry name" value="PCI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00753">
        <property type="entry name" value="PAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50250">
        <property type="entry name" value="PCI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="PCI" evidence="3">
        <location>
            <begin position="208"/>
            <end position="391"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00025771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50250"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OBZ85376.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="401" mass="46075" checksum="63EDB2D0E86DE107" modified="2016-11-30" version="1">MLRKAPTSVSLTSDDIEAFKKSLKAAQQQSQHEDLDDSRSFFSFDELEALCNRQFESPWADIIFNHIKAVIMIDQDDYVAAFDSQKEVVQGFQRVLPSLTRWCLLSLYTINNELRIIATMADQSLPTVEGQRKKLEEAANVISKSFTACATDRAALNVSKKHGTYCMIGILFRIYFKLKQQNLCKNILRAVKAADLPPLDSFPKSDRVTFRYYLGRLYFLEEDYSKAEHELDLAFQECTNKSLKNKELILQTLLPVKLMRGILPTQNLFNKFPKIGQLYRDLAQSIQKGHVKAFNTALTRSEPLLIRQGTYFAMEKAESIAIRQLFRKVFVIMGFNTRIPISTFKQALTFEGMNIDLEEAEWMLANMIYKGYMKGYLSHEKMFLVLSKDNPFPQVAQVAQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NAR6</accession>
    <name>A0A1C7NAR6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_05795</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000324">
        <property type="protein sequence ID" value="OBZ86151.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NAR6"/>
    <dbReference type="STRING" id="101091.A0A1C7NAR6"/>
    <dbReference type="InParanoid" id="A0A1C7NAR6"/>
    <dbReference type="OrthoDB" id="5378975at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031355">
        <property type="entry name" value="YBL010C/LAA2-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38698">
        <property type="entry name" value="EXPRESSED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38698:SF1">
        <property type="entry name" value="FUNGAL PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17104">
        <property type="entry name" value="YBL010C_LAA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="414"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="594"/>
            <end position="628"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="42"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="97"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="148"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="190"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="209"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="227"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="248"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="264"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="611"/>
            <end position="628"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ86151.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="628" mass="71983" checksum="1239D85816A3B6D8" modified="2016-11-30" version="1">MTTEQDNTLNQLIDLSDSQISQEMEPVKPVVHNLLDMDFTTQDDHVQLTSDDTQKKPEAHQSDPLESQVNKEPKLEKPNHSQIDDLSSVTEEEDTDRNENVDIESADKETTDTHKEDKQRKDSMQSEETDHTQKDALENTAEDEFDDVQEKELGSFDNMKNEEPKEEQKDDFDEFESTRNEEFSSLNDLQENDFEEFDDHQDTQKNDFEEFDENTQENDFDNNQVNIDKELGDFDETQKDEFDDFNDKDEFSFDKPKDGFSDGQNDDFDDFGEFDDNGFVDADNQNDDDFGDFDDFEQETKEVPPPRTPTEADVYVDMLNNDPDQLPDFIHAYLNRIWHKDQDWSVSSPIELNENKHDILVTPCSQDLWNKLSHETAFYNPITGAVGQFQWIRSETNKAYLHALGVTLNYDDKSKIPSKKPLRQSADIKRVSSPPSPSSNPASPRLQTPPRPASVSPNTNNGLRVMTDKMDEGTREAKKEADQEMELDIDIARAYCELTEETIRIFPDVKLNAMVIELSRLQRQAADYLDHLLDQREQLKMDSETYNDLISCIVGHAQRLHVNSKDASPAMVSKKKKANSGTFTNIMRRKTTTTNVQSASMSGGVVGMKKQTPQPAPSNNTNNSRRSM</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NB43</accession>
    <name>A0A1C7NB43_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">D-lactate dehydrogenase (cytochrome)</fullName>
            <ecNumber evidence="9">1.1.2.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">DLD</name>
        <name evidence="12" type="ORF">A0J61_05602</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>(R)-lactate + 2 Fe(III)-[cytochrome c] = 2 Fe(II)-[cytochrome c] + pyruvate + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:13521"/>
            <dbReference type="Rhea" id="RHEA-COMP:10350"/>
            <dbReference type="Rhea" id="RHEA-COMP:14399"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16004"/>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
            <dbReference type="ChEBI" id="CHEBI:29034"/>
            <dbReference type="EC" id="1.1.2.4"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the FAD-binding oxidoreductase/transferase type 4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.2.4" evidence="9"/>
    <dbReference type="EMBL" id="LUGH01000307">
        <property type="protein sequence ID" value="OBZ86345.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NB43"/>
    <dbReference type="STRING" id="101091.A0A1C7NB43"/>
    <dbReference type="InParanoid" id="A0A1C7NB43"/>
    <dbReference type="OrthoDB" id="7786253at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004458">
        <property type="term" value="F:D-lactate dehydrogenase (cytochrome) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008720">
        <property type="term" value="F:D-lactate dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1903457">
        <property type="term" value="P:lactate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.465.10:FF:000014">
        <property type="entry name" value="D-lactate dehydrogenase (Cytochrome), putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.45.10:FF:000001">
        <property type="entry name" value="D-lactate dehydrogenase mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.2740:FF:000001">
        <property type="entry name" value="D-lactate dehydrogenase mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.465.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.2740">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.45.10">
        <property type="entry name" value="Vanillyl-alcohol Oxidase, Chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004113">
        <property type="entry name" value="FAD-bd_oxidored_4_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016166">
        <property type="entry name" value="FAD-bd_PCMH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036318">
        <property type="entry name" value="FAD-bd_PCMH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016169">
        <property type="entry name" value="FAD-bd_PCMH_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016164">
        <property type="entry name" value="FAD-linked_Oxase-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006094">
        <property type="entry name" value="Oxid_FAD_bind_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016171">
        <property type="entry name" value="Vanillyl_alc_oxidase_C-sub2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11748">
        <property type="entry name" value="D-LACTATE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11748:SF111">
        <property type="entry name" value="D-LACTATE DEHYDROGENASE, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02913">
        <property type="entry name" value="FAD-oxidase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01565">
        <property type="entry name" value="FAD_binding_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56176">
        <property type="entry name" value="FAD-binding/transporter-associated domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55103">
        <property type="entry name" value="FAD-linked oxidases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51387">
        <property type="entry name" value="FAD_PCMH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0274">FAD</keyword>
    <keyword evidence="4" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="8" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="FAD-binding PCMH-type" evidence="11">
        <location>
            <begin position="110"/>
            <end position="288"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008000"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00038897"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00051436"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="OBZ86345.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="534" mass="58552" checksum="264C741D201422C5" modified="2016-11-30" version="1">MSSARQAFRYIYKRLYQTRHTPKSTLVRNTNYAALGITALIAGSSGYWLANKSVALDAPKQSRVPVPKVPTQNVIAQAYRELCHILPEGHVTVDEEILNEHGYSNNSYHNEGAPNIVVYPKSTEQVAAIVTVANRHDMPIIPFSGGTSLEGHFSAPKGGICISFVEHMDQIVAYHPEDMDIVVQPGVQWEDLNLFLKKEGLFFPMDPGPGACIGGMVGTSCSGTQAVRYGTMREWVINLTVVTPEGKVLKTRQRPRKSSAGYDLTKLFIGSEGTLGVVTEITLKLAVLPKVETVAVCQFPTVRDAAAVVPDLVRAGIQIGAVELLDAAMMKAINLANPELGHNETPTLFFKFSGASQLTVDHDIEIVSTIAKKHQGSQFRYAKSDAEKQLLWEGRKIALWSSTLLKPGSSVWTTDVVVPVSRLPDLIAETQAETNQSFLPCPMVGHVGDGNFHVFLLFDKNNEAEYNEAKRLNNNLVQRAIRMEGSVTGEHGVGIGKKKYLKQELGENTIDLMKKIKVALDPKGLMNPEKVLPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NBN4</accession>
    <name>A0A1C7NBN4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">BZIP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">A0J61_05781</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000323">
        <property type="protein sequence ID" value="OBZ86169.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NBN4"/>
    <dbReference type="InParanoid" id="A0A1C7NBN4"/>
    <dbReference type="OrthoDB" id="2257100at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd12193">
        <property type="entry name" value="bZIP_GCN4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000837">
        <property type="entry name" value="AP-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004827">
        <property type="entry name" value="bZIP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046347">
        <property type="entry name" value="bZIP_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23351:SF24">
        <property type="entry name" value="ACTIVATING TRANSCRIPTION FACTOR 3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23351">
        <property type="entry name" value="FOS TRANSCRIPTION FACTOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07716">
        <property type="entry name" value="bZIP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00338">
        <property type="entry name" value="BRLZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57959">
        <property type="entry name" value="Leucine zipper domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50217">
        <property type="entry name" value="BZIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00036">
        <property type="entry name" value="BZIP_BASIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="BZIP" evidence="6">
        <location>
            <begin position="223"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="187"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="242"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="187"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="220"/>
            <end position="232"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OBZ86169.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="302" mass="31930" checksum="4139A094CE2130C6" modified="2016-11-30" version="1">MSSITHTPIDTQKMPQDVFSQLYQALSPATGAPAQESSSVFDEWLKQDFLSEYSANSSPEIATPLDQFLMSPPYDAKEEVDVSNACLFDNVDLDVSAILESPTPQFFLPAAPTTSETSVSPPTPAVSVSATPAVTSAVATPTPDNMASLFADIGESLPAALAALAAVASPSALLSAATGTTTASAAMSPATASARSPAFSASPARSRKRASEEIDPADDAAVKRQKNTDAARRSRLRKVQKMESLELRVSELEKINAGLLMRVAVLDSEKTNLKAKESSYESRIKVLEEQLAEAHKALSSRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NBZ2</accession>
    <name>A0A1C7NBZ2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">alpha-galactosidase</fullName>
            <ecNumber evidence="2">3.2.1.22</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">agaR_1</name>
        <name evidence="5" type="ORF">A0J61_07077</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>Hydrolysis of terminal, non-reducing alpha-D-galactose residues in alpha-D-galactosides, including galactose oligosaccharides, galactomannans and galactolipids.</text>
            <dbReference type="EC" id="3.2.1.22"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.22" evidence="2"/>
    <dbReference type="EMBL" id="LUGH01000460">
        <property type="protein sequence ID" value="OBZ84874.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NBZ2"/>
    <dbReference type="STRING" id="101091.A0A1C7NBZ2"/>
    <dbReference type="InParanoid" id="A0A1C7NBZ2"/>
    <dbReference type="OrthoDB" id="5795902at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004557">
        <property type="term" value="F:alpha-galactosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016052">
        <property type="term" value="P:carbohydrate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd14791">
        <property type="entry name" value="GH36"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050985">
        <property type="entry name" value="Alpha-glycosidase_related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002252">
        <property type="entry name" value="Glyco_hydro_36"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43053:SF3">
        <property type="entry name" value="ALPHA-GALACTOSIDASE C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43053">
        <property type="entry name" value="GLYCOSIDASE FAMILY 31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02065">
        <property type="entry name" value="Melibiase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OBZ84874.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="741" mass="84647" checksum="F6264722C81D481A" modified="2016-11-30" version="1">MEFNIKNFETAKSQVSLSYKVANKREPIQNRNELLDTVTPYKNEYVQVTSKVVPHTDGKGGYILSISIKALQDLEMVGFETTYAVNLKDQRMMANGFQSWSQARELTKNDKISAIRSSVARYTQYNLQGDYDIFQHSGEKGMIHSSSYTHFRDVINVVTFFGSVSENYGYTYFKSDFNSNKFSIYKDVVGKTMKQNQEIEFVRVFMAQGINAEAAVWDSYAEFYEDRRAVKDNDVAKRHVNGWTSWYNYYGDVSEAIINENVEALQNHQYSIDIFQIDDGFQTAIGDWLDINNKFPSGMKAVADKIKSAGFKAGLWLAPYAVGFNSKVARDHPNWLIIDPETNKPVVAGPNWGGFYALDIYNNEARNYLKKVFDEVLQVWGFDMLKLDFCFAAAMIPRNGKSRGEIMWEAMELIRDLVGPNKLVLGCGVPLASAFRKVDYCRIGSDVAPWWEDSKLKLLHVRERVSTANSLVSTLSRWIMSDRMFGNDPDVMILRKHKNKLTEDERYTLCVLNNILGALVFISDNVKQYGQDEHLLYAATFPKAISRAYSVIEFRTNCFVINFFVNDKNGKQRRYTTFANLSDDEQTIYLPQSSDDTNLLFATDNNMHMSQPDVSEALFYHPSSSVKLKVHETKTFMHIPPPSEESKLVFMGSTSHIVPGTEIDEFGVNDKQDIKITFKKENKRRHKIFVGYGPYLHKGRQAAPPKCTINGKLAQHEWIPVGGVGEGREKSEVLVFVLEEY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NC05</accession>
    <name>A0A1C7NC05_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Urease accessory protein UreD</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">ureD</name>
        <name evidence="3" type="ORF">A0J61_05294</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UreD family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000282">
        <property type="protein sequence ID" value="OBZ86652.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NC05"/>
    <dbReference type="FunCoup" id="A0A1C7NC05">
        <property type="interactions" value="44"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NC05"/>
    <dbReference type="InParanoid" id="A0A1C7NC05"/>
    <dbReference type="OrthoDB" id="5550464at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016151">
        <property type="term" value="F:nickel cation binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01384">
        <property type="entry name" value="UreD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002669">
        <property type="entry name" value="UreD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33643">
        <property type="entry name" value="UREASE ACCESSORY PROTEIN D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33643:SF1">
        <property type="entry name" value="UREASE ACCESSORY PROTEIN D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01774">
        <property type="entry name" value="UreD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0143">Chaperone</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ86652.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="330" mass="37709" checksum="51EE187653B240A0" modified="2016-11-30" version="1">MKRFTSTAENMPGKGILICHCYHDQTKFERIHAQYPLKFIPTTGHAERLAVVYMLSYGGGVISGDQFDIDIEVKKNAILLLMTQGNTKIFKDRLHQQQWLASLQDQRPTFQFTHSVEKVAPSVQTIQSVVQSNATLLVLPDPVTCFRDSSFESRQDFRLEDTSAQLVLLDWFTSGRMTRGENWSFRHYSSRIDVRVGSRLVIKDAMVLDDEEYMRQTPGETAYANRLKPYTCFATLIIISATDKEKSSLQLSVDYLQAKTEKMRLMPLSLKSKEDRQVLWSVSPILKGRGTLVRIAGMTTEQVRDFVKYECLGQGLQQIIGEGMFKKILM</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NC73</accession>
    <name>A0A1C7NC73_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_05374</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000288">
        <property type="protein sequence ID" value="OBZ86580.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NC73"/>
    <dbReference type="InParanoid" id="A0A1C7NC73"/>
    <dbReference type="OrthoDB" id="5516192at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ86580.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="71" mass="8278" checksum="63A9032988FDE68F" modified="2016-11-30" version="1">MSKEGQEKFVFNKQSNHPDTKPHQHRCNAHLEDFLEGILAFDLVKPFGVFLDCLRSQPGQEPPRYQPKDKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NCI3</accession>
    <name>A0A1C7NCI3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Exonuclease mut-7</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">EXD3</name>
        <name evidence="3" type="ORF">A0J61_05122</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000268">
        <property type="protein sequence ID" value="OBZ86827.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NCI3"/>
    <dbReference type="STRING" id="101091.A0A1C7NCI3"/>
    <dbReference type="InParanoid" id="A0A1C7NCI3"/>
    <dbReference type="OrthoDB" id="5376140at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008408">
        <property type="term" value="F:3'-5' exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006139">
        <property type="term" value="P:nucleobase-containing compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002562">
        <property type="entry name" value="3'-5'_exonuclease_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052408">
        <property type="entry name" value="Exonuclease_MUT-7-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47765">
        <property type="entry name" value="3'-5' EXONUCLEASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47765:SF2">
        <property type="entry name" value="EXONUCLEASE MUT-7 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01612">
        <property type="entry name" value="DNA_pol_A_exo1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00474">
        <property type="entry name" value="35EXOc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0540">Nuclease</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="3'-5' exonuclease" evidence="2">
        <location>
            <begin position="619"/>
            <end position="802"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="262"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="19"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="268"/>
            <end position="290"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00474"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ86827.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="815" mass="92623" checksum="F21FAEF9BD131BD2" modified="2016-11-30" version="1">MTHSNGLLDSDEEWEFTSIPVQKKSSPSLSSGKTKKRPTLSEASFRTIRASLPKSTTSFKTRHATASPLPTMVASAPITPLSTPDIPERPMSANIPSTDTNLSLQYISDDELEKICQQMNADLLIRRLIQVYKSHEIYLKIREIETASSFIEARLANHLHFCTNPGDFILNTLSALSTYFTEHARNKELSTRFRRLLTTSLCTALDRFLNTSLEAQRTKCAELAKTEEETKEVDLISFDDQISTITKETDLISFEDQVLETAVAESSSSDDEEEEEEEEEEEESDDDEDNVITLAQMLGISEDFMCRFSLRPEHQQKLIEMIDTISSPVIIYYAMDVFKLSDCIAKGCAHEEEGAKLCRILIKHGHYDEAIICVRRLDLFDWFPVSSTADQFLTAGYGPHLLLFYQDQHELQRELVRFVNKQLRFTYAGNLDIVPARYFEDLYDGTDKTPQLSRLKERKFQKDLVTCGAKLIKELEMDETSDDCYFIMLSQRYSTLRFILAQRAIQQLEDNDISIVSSANFNGLIDLVCEDDPVMARLAIKEMIDMGDTNAPPYFASLYKQQEFYCRYNALPLNQRLLGTVKGELMSRHRSTLTPKKTKNTKLPEKVYQLPAKAKCVMVNSGETLMQMKNVLSTSTICGLDTEWVPAFAKTGVVKTALMQIATDIDGYVFLVDFKTLFEPEHAKLLHLAQVILGLLFEDDQILKIAFDFSGDLDLLHSSMSSSKAWKLRNMLDLKSIETKQGTAMVGGLSGVVAEYLDCSLNKRQQLSNWEKRPLSPEQIVYASCDAYCLLDIFYVLKKSNHPFLRKLNRLGPIH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NCJ6</accession>
    <name>A0A1C7NCJ6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_05161</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000271">
        <property type="protein sequence ID" value="OBZ86791.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NCJ6"/>
    <dbReference type="InParanoid" id="A0A1C7NCJ6"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="20"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ86791.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="84" mass="9773" checksum="E0B793AAC562315F" modified="2016-11-30" version="1">MVVMCDRYKYQQRKTETKSNKKQHDKKKAALYRRRKVDETSSAANVFTVCEEPSQLLDLIVMSMYEVLPSDKSESLLIDAKDLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NCK1</accession>
    <name>A0A1C7NCK1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">SAGA-associated factor 29</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">CCDC101</name>
        <name evidence="6" type="ORF">A0J61_05451</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000294">
        <property type="protein sequence ID" value="OBZ86499.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NCK1"/>
    <dbReference type="FunCoup" id="A0A1C7NCK1">
        <property type="interactions" value="20"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NCK1"/>
    <dbReference type="InParanoid" id="A0A1C7NCK1"/>
    <dbReference type="OrthoDB" id="10265994at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000124">
        <property type="term" value="C:SAGA complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd20393">
        <property type="entry name" value="Tudor_SGF29_rpt1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd20394">
        <property type="entry name" value="Tudor_SGF29_rpt2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.140">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037802">
        <property type="entry name" value="SGF29"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010750">
        <property type="entry name" value="SGF29_tudor-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047288">
        <property type="entry name" value="Tudor_SGF29_rpt1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047287">
        <property type="entry name" value="Tudor_SGF29_rpt2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21539">
        <property type="entry name" value="SAGA-ASSOCIATED FACTOR 29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21539:SF0">
        <property type="entry name" value="SAGA-ASSOCIATED FACTOR 29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07039">
        <property type="entry name" value="SGF29_Tudor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51518">
        <property type="entry name" value="SGF29_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="SGF29 C-terminal" evidence="5">
        <location>
            <begin position="123"/>
            <end position="261"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51518"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OBZ86499.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="261" mass="30308" checksum="D4C71245479C101E" modified="2016-11-30" version="1">MERKSRSSRIHDDLNDESNLWKQICSSLFKLEGIQREEEGIINTINKVQLSLDSEKVSNNILQQKLKDNYRRGIELSTHETRIIQDVIEKLSVLIALRDSEQDQKRKRRKLENDSKTLGNGNSSYVFTKGTTVAARQPSKEKDKSEEWILAVVIQYHADKNKYEVEDVDQDDYGEKQRYMLPPRYVIPVLSSEEARLSPEIPAQQDVLALYPGTTCFYKATVVAPPSKSKEIKNYRVRFEDDNNEVKYVMPEHVLEMPKTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NDR0</accession>
    <name>A0A1C7NDR0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">A0J61_04728</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000238">
        <property type="protein sequence ID" value="OBZ87221.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="FunCoup" id="A0A1C7NDR0">
        <property type="interactions" value="470"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NDR0"/>
    <dbReference type="InParanoid" id="A0A1C7NDR0"/>
    <dbReference type="OrthoDB" id="5330228at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006974">
        <property type="term" value="P:DNA damage response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000209">
        <property type="term" value="P:protein polyubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd18793">
        <property type="entry name" value="SF2_C_SNF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10810">
        <property type="entry name" value="Tandem AAA-ATPase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052583">
        <property type="entry name" value="ATP-helicase/E3_Ub-Ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059033">
        <property type="entry name" value="C144_05_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038718">
        <property type="entry name" value="SNF2-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049730">
        <property type="entry name" value="SNF2/RAD54-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000330">
        <property type="entry name" value="SNF2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45865:SF1">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE SHPRH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45865">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE SHPRH FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26021">
        <property type="entry name" value="Ferritin_C144_05"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00176">
        <property type="entry name" value="SNF2-rel_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13920">
        <property type="entry name" value="zf-C3HC4_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="7">
        <location>
            <begin position="197"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="domain" description="RING-type" evidence="6">
        <location>
            <begin position="982"/>
            <end position="1020"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="8">
        <location>
            <begin position="1086"/>
            <end position="1236"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="16"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="27"/>
            <end position="49"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OBZ87221.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="1259" mass="145367" checksum="6AB07DCF944FFE07" modified="2016-11-30" version="1">MTPLLSVVSKKLGFPKPVTLLRDPSSPHASTSQSTAQISLPSTNTSPRASSEKVPLSEPTSPPPSVVQKLPPLSRPVSLLDFDPTSTVSFPSAELPTHHSVESFLRYLQPPVSDTVLSNYVSPSIVAELTPFQTQNVEWMMAREAHYADNKGLVQPNNAIFEHLPLLYAGNHLDNQKGHYLNLLTDTVLTDRSKINEPIKQSFRGGILADEMGLGKTISVLALIAKHKLNQQDLFHPHEDKDLLVSPGTLIIAPGPIISQWSSEIEKHAPSLSYFVYQGRRVHPDMDNEALLQYDIVLTHYEAFRHEIYYTKPLPKRPQRSGVAYKRQYQMSPLVSIRWFRCILDEAQMIDASLSHVSAVAKLIPSWYRWAVTGTPLKDDLNNLYSLYDFLELEDTLTANRFEILCQRKSHFYPFAKQTIRRNMKSKLKDQVHIPHQSRHXVHIPFSTIEQHYYEDLWRDCRQELRLDWFDSIHWTLPENVYPATAQTYHTLRLKMRQWLLALRQACIHPSMITNTSMRLGYQSSGYNKKAQSMDQVLDYMHQSAEEQLDGNQHAYYLQQLKKGGMYECLQSWQEAINLYLTHLVSVEQLANHYQTHKLSLSEQEKNSSARRVYRWQMLLHRYYFYAAGVYHILERKDQEEIYYDKASQLRRSLMESYTSKVFELMHEMEKTADHVGLKEDYLLGARTLDVGLLDAIEYEDDHLNDSDHEDAQSDDSFQLRNQRASDLNTLENVKGLGDVLDRQLRKIVYIREQMMPLLKKSLVDNQNETDEVTGDEYESSLIEQEMCQVYLSAYQTLLEDRRFIVKGTTVNAHETMPVEGLPHMSTEAKSVEQVEKAYRHQLKQPGFEIECIKDVESELRALKQRIHKDPNHLEFYRLIDVEHQHLVSHLPCQHKLMDALENDFKRLNQLFNSRVAYYKYLQTISDTLTEWSHPSPRPEIEKLNIALEKLEEKIAQGKSRTLYFKALLEEQEALNKTPKECLICQESFEKGLITYCGHICCHDCGMKWFKTSQRCHTCNSPVRANEWYTIYNPILLLISFSIAYKRTEMRNKDTITKPQENVPTDLMKEIEKQCIIEGQGAKLDAIIRHIKYIKTMSNGKCVVFSQWAKVLDMLKQGLKANGIKFLSLNTGAALNRNNVTKFQNDPDINVILLHARSQSSGLTLVAAQTVFIIEPVLNEAMEKQAINRIHRIGQTKETSVFWYIVQDTIEERIQAIHDVKRQMEPETTQVLSTMADGGGEFVSNDDIQRCFTSDPNFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NDR9</accession>
    <name>A0A1C7NDR9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">General transcription and DNA repair factor IIH subunit TFB5</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">TFB5</name>
        <name evidence="9" type="ORF">A0J61_04856</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">In NER, TFIIH acts by opening DNA around the lesion to allow the excision of the damaged oligonucleotide and its replacement by a new DNA fragment. In transcription, TFIIH has an essential role in transcription initiation. When the pre-initiation complex (PIC) has been established, TFIIH is required for promoter opening and promoter escape.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Component of the 7-subunit TFIIH core complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 8">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the TFB5 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000247">
        <property type="protein sequence ID" value="OBZ87100.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NDR9"/>
    <dbReference type="FunCoup" id="A0A1C7NDR9">
        <property type="interactions" value="78"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NDR9"/>
    <dbReference type="InParanoid" id="A0A1C7NDR9"/>
    <dbReference type="OrthoDB" id="354at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000439">
        <property type="term" value="C:transcription factor TFIIH core complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005675">
        <property type="term" value="C:transcription factor TFIIH holo complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006294">
        <property type="term" value="P:nucleotide-excision repair, preincision complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006367">
        <property type="term" value="P:transcription initiation at RNA polymerase II promoter"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1220">
        <property type="entry name" value="TFB5-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035935">
        <property type="entry name" value="TFB5-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009400">
        <property type="entry name" value="TFIIH_TTDA/Tfb5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28580">
        <property type="entry name" value="GENERAL TRANSCRIPTION FACTOR IIH SUBUNIT 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28580:SF1">
        <property type="entry name" value="GENERAL TRANSCRIPTION FACTOR IIH SUBUNIT 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06331">
        <property type="entry name" value="Tfb5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01395">
        <property type="entry name" value="Tbf5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF142897">
        <property type="entry name" value="TFB5-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 8" id="KW-0227">DNA damage</keyword>
    <keyword evidence="6 8" id="KW-0234">DNA repair</keyword>
    <keyword evidence="7 8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0804">Transcription</keyword>
    <keyword evidence="4 8" id="KW-0805">Transcription regulation</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007470"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU368032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OBZ87100.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="75" mass="8675" checksum="8CBF88B59EB5F48D" modified="2016-11-30" version="1">MVKAVKGVLLECDSTVKQIVLNLNKRGNFIIEDLDETHLFIEASWVEQLKYELDKILDENSYTVSAVDEKDNKKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NDV2</accession>
    <name>A0A1C7NDV2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Prolyl endopeptidase</fullName>
            <ecNumber evidence="6">3.4.21.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">ptrB</name>
        <name evidence="9" type="ORF">A0J61_04996</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Serine peptidase whose precise substrate specificity remains unclear. Does not cleave peptides after a arginine or lysine residue. Regulates trans-Golgi network morphology and sorting by regulating the membrane binding of the AP-1 complex. May play a role in the regulation of synaptic vesicle exocytosis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the peptidase S9A family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.21.-" evidence="6"/>
    <dbReference type="EMBL" id="LUGH01000258">
        <property type="protein sequence ID" value="OBZ86949.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NDV2"/>
    <dbReference type="STRING" id="101091.A0A1C7NDV2"/>
    <dbReference type="InParanoid" id="A0A1C7NDV2"/>
    <dbReference type="OrthoDB" id="248387at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.120">
        <property type="entry name" value="Prolyl oligopeptidase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023302">
        <property type="entry name" value="Pept_S9A_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001375">
        <property type="entry name" value="Peptidase_S9_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002470">
        <property type="entry name" value="Peptidase_S9A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051543">
        <property type="entry name" value="Serine_Peptidase_S9A"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11757:SF19">
        <property type="entry name" value="PROLYL ENDOPEPTIDASE-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11757">
        <property type="entry name" value="PROTEASE FAMILY S9A OLIGOPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00326">
        <property type="entry name" value="Peptidase_S9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02897">
        <property type="entry name" value="Peptidase_S9_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00862">
        <property type="entry name" value="PROLIGOPTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50993">
        <property type="entry name" value="Peptidase/esterase 'gauge' domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 6 9" id="KW-0645">Protease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6" id="KW-0720">Serine protease</keyword>
    <feature type="domain" description="Peptidase S9A N-terminal" evidence="8">
        <location>
            <begin position="39"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S9 prolyl oligopeptidase catalytic" evidence="7">
        <location>
            <begin position="499"/>
            <end position="722"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="724"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005228"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00045448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU368024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02897"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OBZ86949.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="724" mass="83290" checksum="BB1AFA28E8275EAE" modified="2016-11-30" version="1" fragment="single">AIQRKGSIWIPRQQPQARPIFTSLKHVFSKKPVKIPKPRPVTNIQTHHGRQREDSFSWMENLSDQHINTYIQAENDYTKQMMRQHKFLEKIILREMKRKLQVPNALPPLKTVSNGYEYYSTTSSYGMVYLRKKLGEGRDAPEQVLLNTGFLRSMNMGVRKVLLSPDHSLFAYNTEREGMEYGELHFKDLNNSSEWAQNEVLGNVFNFVWANNRVVYYTVPNEQLRPFQVYAHLMGTDQSEDILVFEEPDDTVFVDITCSKDNKFIHINANTLSSSEVRVVSTDHNFSKSSKPLVQLIEPRVPGIEYYVDHHHDTFYILTNADGATNFKLVKTSDHTLQRKYWQDVVTMKATEKIEDVDLFQRHIIVYGKRDGLPMMLCHDLVTHQTHSVKLPEKFCVLYPGTNLDFHTDQVRFSIQSPFMHESTFEYDMSTQKLSPVRVQPVKNFDKSNYTCSQVHVPSHDGKKVPVTLLHKKEIKLNGKNPVLMRSYGAYGTCTDIDFRVEQFPLLERGWVIALPHVRGGSELGRDWYEEGKLKNKMNSFKDFIAVAEHLVDSKLTSPEHLTAMGTSAGGLLVGAMLHMRPDLFKALLLKVPFVDPLSAMLDPSLPLTQIEYPEWGNPTDDPEAYDLIESYAPYDNIHPHLFSDHTSFPSVYITGGMKDQRVAYWQPLKLMARLRHSMPAQYPSTALLQMDLDRGHFSGAEQESRLSDLAQQMAFLITQVNTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NF76</accession>
    <name>A0A1C7NF76_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Transcriptional coactivator hfi1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">hfi1</name>
        <name evidence="6" type="ORF">A0J61_04247</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000203">
        <property type="protein sequence ID" value="OBZ87708.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NF76"/>
    <dbReference type="FunCoup" id="A0A1C7NF76">
        <property type="interactions" value="30"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NF76"/>
    <dbReference type="InParanoid" id="A0A1C7NF76"/>
    <dbReference type="OrthoDB" id="10264870at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000124">
        <property type="term" value="C:SAGA complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003713">
        <property type="term" value="F:transcription coactivator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd22933">
        <property type="entry name" value="HFD_HFI1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024738">
        <property type="entry name" value="Hfi1/Tada1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21277">
        <property type="entry name" value="TRANSCRIPTIONAL ADAPTER 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21277:SF5">
        <property type="entry name" value="TRANSCRIPTIONAL ADAPTER 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12767">
        <property type="entry name" value="SAGA-Tad1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OBZ87708.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="307" mass="34823" checksum="131FCFF19D6E4665" modified="2016-11-30" version="1">MTVLNKDDTTSFHSKPPVNHKSHFAHPTANGRQDVLALKQQLADALGENGPLYWDALRDFVMGKLNRQEFDFYANLYLNRQHAHLHNAFILSTVHNAQANTPPPSKHRLVGWAKRKRGKEGIVDEFEQDPRKQKLKSDVMSLSKADRERLKTLVKSGEKNKLRPYVDQLLGARVSRPPILPVALNQLPPQYSQEYSKGLMAPLCIDLKELPTPETLHARMTSIALENGLLGGVGEDVVNVMLFAAENYIKSSITSAICKRRTNRCIGVQMPKKEEKEEQQKEEETSITLKDLAFSYRITPYIVMKKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NF87</accession>
    <name>A0A1C7NF87_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Ubiquitin-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_04195</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000199">
        <property type="protein sequence ID" value="OBZ87755.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NF87"/>
    <dbReference type="STRING" id="101091.A0A1C7NF87"/>
    <dbReference type="InParanoid" id="A0A1C7NF87"/>
    <dbReference type="OrthoDB" id="2248860at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd17039">
        <property type="entry name" value="Ubl_ubiquitin_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000626">
        <property type="entry name" value="Ubiquitin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00240">
        <property type="entry name" value="ubiquitin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50053">
        <property type="entry name" value="UBIQUITIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ubiquitin-like" evidence="1">
        <location>
            <begin position="3"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ87755.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="143" mass="16428" checksum="41656C3820341477" modified="2016-11-30" version="1">MNFQVIVNSFAGFGPFCLCFKYDEPCTVYDLKKKLAATTAFSVEEQRIRSLGGRILTDSDNLLQNYRIHDGPIVLNLTVRLIGGRMQRDEPMQINQERQPRPLLKKIRLEGTAQVLLHHSRVNDTALERIDKGKGKETCKRKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NH21</accession>
    <name>A0A1C7NH21_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">fructose-2,6-bisphosphate 2-phosphatase</fullName>
            <ecNumber evidence="2">3.1.3.46</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">FBP26_2</name>
        <name evidence="9" type="ORF">A0J61_04096</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">In the C-terminal section; belongs to the phosphoglycerate mutase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.46" evidence="2"/>
    <dbReference type="EMBL" id="LUGH01000193">
        <property type="protein sequence ID" value="OBZ87846.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NH21"/>
    <dbReference type="FunCoup" id="A0A1C7NH21">
        <property type="interactions" value="282"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NH21"/>
    <dbReference type="InParanoid" id="A0A1C7NH21"/>
    <dbReference type="OrthoDB" id="267323at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003873">
        <property type="term" value="F:6-phosphofructo-2-kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004331">
        <property type="term" value="F:fructose-2,6-bisphosphate 2-phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006003">
        <property type="term" value="P:fructose 2,6-bisphosphate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006000">
        <property type="term" value="P:fructose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07067">
        <property type="entry name" value="HP_PGM_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1240:FF:000005">
        <property type="entry name" value="GpmB, Fructose-2,6-bisphosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000644">
        <property type="entry name" value="GpmB, Fructose-2,6-bisphosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1240">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003094">
        <property type="entry name" value="6Pfruct_kin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013079">
        <property type="entry name" value="6Phosfructo_kin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013078">
        <property type="entry name" value="His_Pase_superF_clade-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029033">
        <property type="entry name" value="His_PPase_superfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10606:SF44">
        <property type="entry name" value="6-PHOSPHOFRUCTO 2-KINASE_FRUCTOSE 2,6-BISPHOSPHATASE LONG FORM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10606">
        <property type="entry name" value="6-PHOSPHOFRUCTO-2-KINASE/FRUCTOSE-2,6-BISPHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01591">
        <property type="entry name" value="6PF2K"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00300">
        <property type="entry name" value="His_Phos_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000709">
        <property type="entry name" value="6PFK_2-Ptase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00991">
        <property type="entry name" value="6PFRUCTKNASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00855">
        <property type="entry name" value="PGAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53254">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="6-phosphofructo-2-kinase" evidence="8">
        <location>
            <begin position="4"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="active site" description="Tele-phosphohistidine intermediate" evidence="6">
        <location>
            <position position="224"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor/acceptor" evidence="6">
        <location>
            <position position="294"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="223"/>
            <end position="230"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="274"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013067"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR613078-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR613078-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01591"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OBZ87846.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="461" mass="52982" checksum="E245449253D0438E" modified="2016-11-30" version="1">MSTLQKDLRIACVMVGLPARGKTYISCKVCRYLTWLGIKTQIFTVSNYRRKLAGLNMPHTFFDTHNTEAMKVRHQAASMALGDMIRWFEKENGTVGILDATNSTKQGRAWINQELTSRDIQVLFIESICDDENVIMSNIKDVKLSSPDYCNRDPEEATDDFMQRIRHYEAAYETVTEQELTYIKLINVGSQYIINMIRGYLESRIVYYLMNLHTRPKRIWFSRHGESMFNLEDRIGGDAGLSPRGEQYALKLPELVRENIGDRPLTVWTSSMTRTIQTARHLPFPKKQWKALDELDTGVCDGMTYDEIAAKYPDDFARRDEDKFNYRYRGGESYRDLVLRLEPVIMDLERHENILIISHQATIRCMYAYFMGLSHEELPYARIPLHTIIELKPKAFSCEEKLYKIDVGAVDTFRPKGQLGRRLTNDKFVSTVPALAEGASGEIADSNKPILPIAPISVTPC</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NHK7</accession>
    <name>A0A1C7NHK7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_03359</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000143">
        <property type="protein sequence ID" value="OBZ88587.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NHK7"/>
    <dbReference type="InParanoid" id="A0A1C7NHK7"/>
    <dbReference type="OrthoDB" id="2279290at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003903">
        <property type="entry name" value="UIM_dom"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50330">
        <property type="entry name" value="UIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="128"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="28"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="173"/>
            <end position="184"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ88587.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="201" mass="23377" checksum="86896AE7776CBCA2" modified="2016-11-30" version="1">MAKKKPQTLQELFQKAAKRSTPDDQEERELQKALELSKREQVNEQRRLLAQFSQHNSIPKQIKQEEPLLEITDLSAFLNASDTEEEPISTSILIDDESDHESPFAKERLDWQGDATVISDSDCSVIDLVDPDNSSKPKDDDGYLSPLEGFTNIKENRDDAQFNPFFQQLETTKKRRTTTKKKKPAYKSKWYFVNKRKRKKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NHP8</accession>
    <name>A0A1C7NHP8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Cell cycle checkpoint protein RAD17</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">RAD17</name>
        <name evidence="9" type="ORF">A0J61_03289</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the rad17/RAD24 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000139">
        <property type="protein sequence ID" value="OBZ88643.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NHP8"/>
    <dbReference type="STRING" id="101091.A0A1C7NHP8"/>
    <dbReference type="InParanoid" id="A0A1C7NHP8"/>
    <dbReference type="OrthoDB" id="10265971at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003682">
        <property type="term" value="F:chromatin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003689">
        <property type="term" value="F:DNA clamp loader activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000077">
        <property type="term" value="P:DNA damage checkpoint signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033314">
        <property type="term" value="P:mitotic DNA replication checkpoint signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00009">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18140">
        <property type="entry name" value="HLD_clamp_RFC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004582">
        <property type="entry name" value="Checkpoint_prot_Rad17_Rad24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057927">
        <property type="entry name" value="RAD24-like_helical"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047854">
        <property type="entry name" value="RFC_lid"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12172">
        <property type="entry name" value="CELL CYCLE CHECKPOINT PROTEIN RAD17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12172:SF0">
        <property type="entry name" value="CELL CYCLE CHECKPOINT PROTEIN RAD17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03215">
        <property type="entry name" value="Rad17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25812">
        <property type="entry name" value="RAD24_helical"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="4" id="KW-0227">DNA damage</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Checkpoint protein RAD24-like helical bundle" evidence="8">
        <location>
            <begin position="249"/>
            <end position="330"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006168"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF25812"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OBZ88643.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="427" mass="49433" checksum="10CECF5A16E47E31" modified="2016-11-30" version="1">MCMKSDKINLIKSVIQQSSIYRPDPSSTKLLFISGPSGCGKSTLIRLLSQTMSFELVEWQHPSSNSTDHYVSTMRQFEQFINLSIRRHTLSNEFNRKVIFIDDLPDITTPQVRRDFHTILRNCLHIPIPFLMVFVISHAWMTTTQNRHAYETKLNNTMDIIPQELEQDRRVTHIKLNAVSKTLMVKALNRVIQDQDLTVTKPQLDALTEASEGDIRSAINHLQFYAKRQPPQKKRKAKVKAFDEKIGPLDLFHAVGKVLYGKRNPDGTFESKPEHIFDKLPVDPDLFNAFLHQNSLAFFDEIEAVADAFDYLSVADTIRSHLDWQDHHASLYRSLVTMYGLMEKPTKAYSFYRIQRPELFDAQSSARQKKRDDYHEAWMASVAHRTAPFESAEKELLVDDPIEDFSEDEFEEIYGDDAELALLMDQY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NI71</accession>
    <name>A0A1C7NI71_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF7721 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_03148</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000131">
        <property type="protein sequence ID" value="OBZ88801.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NI71"/>
    <dbReference type="STRING" id="101091.A0A1C7NI71"/>
    <dbReference type="InParanoid" id="A0A1C7NI71"/>
    <dbReference type="OrthoDB" id="2290255at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056138">
        <property type="entry name" value="DUF7721"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39477:SF1">
        <property type="entry name" value="BETA-FLANKING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39477">
        <property type="entry name" value="CHROMOSOME 8, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24845">
        <property type="entry name" value="DUF7721"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF7721" evidence="2">
        <location>
            <begin position="33"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="8"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="21"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="48"/>
            <end position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF24845"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ88801.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="226" mass="23509" checksum="FCAB5B15DD77F8CF" modified="2016-11-30" version="1">MSYGESDSYQGGQAASYQGGGEHHSYGGYEKPDVSQAARLAKQHVQQDGDDDDDDDKEGLFSSVLSSLVDRDDDDAPHKQHVNEDEAQTAAQVHNRVYNQNNGQPDEEASSRDLGSAAAMQAFKMFSGGSSGGNGGSNELVGLAMGEAMKLFKAQGGSSGKANQSEMLQSAAMMAMKLLMTQKSGQQQGGGGGLGQVMGILGSLTGGQQQQQHQSSGVAGLLGKFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NIZ1</accession>
    <name>A0A1C7NIZ1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Low-affinity phosphate transporter PHO91</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">PHO91_0</name>
        <name evidence="8" type="ORF">A0J61_02875</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000115">
        <property type="protein sequence ID" value="OBZ89073.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NIZ1"/>
    <dbReference type="STRING" id="101091.A0A1C7NIZ1"/>
    <dbReference type="InParanoid" id="A0A1C7NIZ1"/>
    <dbReference type="OrthoDB" id="10260443at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005315">
        <property type="term" value="F:phosphate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006817">
        <property type="term" value="P:phosphate ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006797">
        <property type="term" value="P:polyphosphate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01115">
        <property type="entry name" value="SLC13_permease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd14478">
        <property type="entry name" value="SPX_PHO87_PHO90_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004680">
        <property type="entry name" value="Cit_transptr-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004331">
        <property type="entry name" value="SPX_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10283:SF92">
        <property type="entry name" value="LOW-AFFINITY PHOSPHATE TRANSPORTER PHO91"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10283">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 13 MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03600">
        <property type="entry name" value="CitMHS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03105">
        <property type="entry name" value="SPX"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51382">
        <property type="entry name" value="SPX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="310"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="340"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="393"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="438"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="480"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="520"/>
            <end position="546"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="566"/>
            <end position="585"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="597"/>
            <end position="614"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="620"/>
            <end position="640"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="661"/>
            <end position="692"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="704"/>
            <end position="727"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="748"/>
            <end position="771"/>
        </location>
    </feature>
    <feature type="domain" description="SPX" evidence="7">
        <location>
            <begin position="1"/>
            <end position="213"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OBZ89073.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="776" mass="86504" checksum="A86DD97F9DB4D0D3" modified="2016-11-30" version="1">MRFSHTLQLNAVPEWVDSYVNYDTLKKLIFQLEKEKVEDMNTAQDPEKVSERREDGEAKFLTALDIQLEKVFDFYTQKESELYTLLDQLESEFANRNLNDHQSTVHKQTLTPLEDIDSTRHLAHRTPSDYPEEKYESVQRRHSHQSFESRMSMDHSDHILVEQLSDMRSQLILLYISLSELESYVELNRTAFEKILKKHDKVLERNLKLQYINKMVKDSRPFMVETMDVLKSQITRVETIFADAFCNGNRQIALRQMKSHLRDQVTFERNTVWKDMVRQERKAHGTKIIEPKVVKSVKIPFVNLSIQSGLFRQLMCFLLALVVFVILLCVNCFNNKQENYCFALLIFAAIMWATEAIPLYATSCMIPFLIVPLQIMRNTSTGEVLTAKAAAKAVFASMFSGTIMMLLGGFALAAALSKYGIAKAFASHVLSRAGTRPMWVLLAIMFVSGFLSMFISNVATPVLCFSLIDPILRTLPDKSRVAPCLILGIALSSCIGGMMSPISSPQNIVTIQYLNPNPGWGLWFAVALPVSILSMLVCWGLLLLVYKPGRDTPHLNTIKAAKEKITWTQVFVMLVTILTIALWCAETSIEYAIGDTGIIAAIPLFVFFGAGILNKDDLNNFLWSVVVLAQGGMALGNAVTSSGLLQDIAVRIKDGIQDLQVIAILAIFSLLILVFATFVSHTVAALIIIPIVKEVGEHLPVPHPNLLVMGAGLACSAGMGLPVSGYPNMSAVMLEDPSGRPYLSTKDFVITGIPTSIICTALVFTLGYGIMSGIGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NJD1</accession>
    <name>A0A1C7NJD1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">type I protein arginine methyltransferase</fullName>
            <ecNumber evidence="1">2.1.1.319</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">rmt1</name>
        <name evidence="9" type="ORF">A0J61_02808</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>L-arginyl-[protein] + S-adenosyl-L-methionine = N(omega)-methyl-L-arginyl-[protein] + S-adenosyl-L-homocysteine + H(+)</text>
            <dbReference type="Rhea" id="RHEA:48100"/>
            <dbReference type="Rhea" id="RHEA-COMP:10532"/>
            <dbReference type="Rhea" id="RHEA-COMP:11990"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29965"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:65280"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="5">
            <dbReference type="Rhea" id="RHEA:48101"/>
        </physiologicalReaction>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.319" evidence="1"/>
    <dbReference type="EMBL" id="LUGH01000111">
        <property type="protein sequence ID" value="OBZ89140.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NJD1"/>
    <dbReference type="FunCoup" id="A0A1C7NJD1">
        <property type="interactions" value="805"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NJD1"/>
    <dbReference type="InParanoid" id="A0A1C7NJD1"/>
    <dbReference type="OrthoDB" id="7848332at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042054">
        <property type="term" value="F:histone methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042802">
        <property type="term" value="F:identical protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035242">
        <property type="term" value="F:protein-arginine omega-N asymmetric methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035241">
        <property type="term" value="F:protein-arginine omega-N monomethyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046656">
        <property type="term" value="P:folic acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006406">
        <property type="term" value="P:mRNA export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0060567">
        <property type="term" value="P:negative regulation of termination of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032968">
        <property type="term" value="P:positive regulation of transcription elongation by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.70.160.11:FF:000001">
        <property type="entry name" value="Blast:Protein arginine N-methyltransferase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.150:FF:000003">
        <property type="entry name" value="Blast:Protein arginine N-methyltransferase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.160.11">
        <property type="entry name" value="Hnrnp arginine n-methyltransferase1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025799">
        <property type="entry name" value="Arg_MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025714">
        <property type="entry name" value="Methyltranfer_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055135">
        <property type="entry name" value="PRMT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11006">
        <property type="entry name" value="PROTEIN ARGININE N-METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11006:SF53">
        <property type="entry name" value="PROTEIN ARGININE N-METHYLTRANSFERASE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13847">
        <property type="entry name" value="Methyltransf_31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22528">
        <property type="entry name" value="PRMT_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51678">
        <property type="entry name" value="SAM_MT_PRMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 6 9" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="3 6 9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransferase" evidence="7">
        <location>
            <begin position="53"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="domain" description="Protein arginine N-methyltransferase" evidence="8">
        <location>
            <begin position="159"/>
            <end position="320"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011925"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00049303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF13847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF22528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OBZ89140.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="336" mass="38047" checksum="C96B05C59677EF5B" modified="2016-11-30" version="1">MSAPTTTDNAGMTSKDYYFDSYAHFGIHEEMLKDEVRTLSYRNSIYNNKHLFKDKVVLDVGCGTGILSMFAAKAGAKHVYGIDMSNIIHQARIIVKDNGLDHKVTLIQGKMEEVVLPVDKVDIIISEWMGYFLLYESMLDTVLVARDKYLAPGGMIFPDKAVMCIAAIEDGDYKEEKIGYWDNVYGFDYSSIKKLALKEPLVDVVEPRCVMSDTCAFKEIDIATVTKEDLTFKAPFKITAERDDYAHAFIAWFDIAFTHCHKPVEFSTGPFAKYTHWKQTVFYTNEALTLKKGDTVEGELTCAPNKSNPRDLDIIIDYKSSATHGEVREVCEYKMS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NJH7</accession>
    <name>A0A1C7NJH7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">SET domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_02685</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000104">
        <property type="protein sequence ID" value="OBZ89277.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NJH7"/>
    <dbReference type="STRING" id="101091.A0A1C7NJH7"/>
    <dbReference type="InParanoid" id="A0A1C7NJH7"/>
    <dbReference type="OrthoDB" id="5984008at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.270.10">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053201">
        <property type="entry name" value="Flavunoidine_N-MTase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001214">
        <property type="entry name" value="SET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046341">
        <property type="entry name" value="SET_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12350">
        <property type="entry name" value="HISTONE-LYSINE N-METHYLTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12350:SF19">
        <property type="entry name" value="SET DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00856">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82199">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SET" evidence="1">
        <location>
            <begin position="66"/>
            <end position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00856"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ89277.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="160" mass="17988" checksum="B289926B8EB9AA06" modified="2016-11-30" version="1">MENSQPSHPGLFKVLRQGKPGSFSSKLVAERDFAKGSVIVDLQGLTPGPKRYSSVQISPTEHVELNSDLLYLNHSCEPSTYLDVSKRSLMALKDIQNGDELTFFYPSTEWDMAQPFDCWCKSDKCVGKVDGARNIPTEKLQQFTLSDHIHQLLKERDTAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NJY2</accession>
    <name>A0A1C7NJY2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">RING-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">A0J61_03152</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000131">
        <property type="protein sequence ID" value="OBZ88796.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NJY2"/>
    <dbReference type="STRING" id="101091.A0A1C7NJY2"/>
    <dbReference type="InParanoid" id="A0A1C7NJY2"/>
    <dbReference type="OrthoDB" id="2358609at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017907">
        <property type="entry name" value="Znf_RING_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23327">
        <property type="entry name" value="RING FINGER PROTEIN 127"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15227">
        <property type="entry name" value="zf-C3HC4_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00518">
        <property type="entry name" value="ZF_RING_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="5">
        <location>
            <begin position="39"/>
            <end position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OBZ88796.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="182" mass="21490" checksum="77855729CEB9A835" modified="2016-11-30" version="1">MTGSESSVLERQLAVVNQLKQRCRRLLQTNHPASADYTCTICLDMLQEPVTLSCDHTFCRACLQRYFCKPCERKRPSESFFSSARRTVYCECYALDAWDRKAACPLCRHPFATSTCRFDADLSRYLALYFPSKEEDETEPKETFYNRIQRWSYRIMQQESIEVDLLEVQNSMNLMTRRSWII</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NK32</accession>
    <name>A0A1C7NK32_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Cytochrome P450</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_02593</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000099">
        <property type="protein sequence ID" value="OBZ89358.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NK32"/>
    <dbReference type="STRING" id="101091.A0A1C7NK32"/>
    <dbReference type="InParanoid" id="A0A1C7NK32"/>
    <dbReference type="OrthoDB" id="1470350at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11069">
        <property type="entry name" value="CYP_FUM15-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050196">
        <property type="entry name" value="Cytochrome_P450_Monoox"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24291:SF175">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24291">
        <property type="entry name" value="CYTOCHROME P450 FAMILY 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0349">Heme</keyword>
    <keyword evidence="2" id="KW-0408">Iron</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" description="axial binding residue" evidence="2">
        <location>
            <position position="491"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ89358.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="543" mass="62003" checksum="8A2C44B0EFCD1584" modified="2016-11-30" version="1">MDYQVVYDTIQKQIEKYILNPTGLEPPAAKKLAIQLGVSTTIVYYFFKFIVYRLYLHPANRLPGPSVGWIPFMGNIAEILREEAGVPHKRWTKQYGPIYYYHTEWNQPRIAVADDELLKQVLVSQEFDFIKTPDTSRFLRRILGNGLLLSEGDEHRHQRRMLNPAFSVNSVRALVPLMAKPGHLLRDIWLKQIKEEQGNKVQSENGEEFTEIEVSSGLSLAALDVIGWAFGQDFKSVEFSGTPQQSKFSQAYLNIFAPNLSFLRILSLLFPVLRYLPTKRNRLMAKHLNWLNEESRNLVQAGVDRAAKEKAEGIKSDKPKDLLATMVNLIDEETGKGFTVEELKEQCLTFLAAGHETTGVGLSWCLWLLAKNQAVQDELREEVRTLFNDDDHVPSYDEINALPLLNNVVRETLRLIPPVPGTLRQTRVPTVIGSYAIPAGVPIFLPLIVLHHSKSIWGEDAEEFVPSRWNNPEKIGNTYQYLPFLAGGRMCIGYKFALIEFKLLLAILIRDIQYFEKPGFKIIKKQQLTLRPAPNMTLWMKAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NKA6</accession>
    <name>A0A1C7NKA6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">phosphopyruvate hydratase</fullName>
            <ecNumber evidence="3">4.2.1.11</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">ENO_1</name>
        <name evidence="13" type="ORF">A0J61_02458</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>(2R)-2-phosphoglycerate = phosphoenolpyruvate + H2O</text>
            <dbReference type="Rhea" id="RHEA:10164"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:58289"/>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
            <dbReference type="EC" id="4.2.1.11"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="10">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="10">Mg(2+) is required for catalysis and for stabilizing the dimer.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1">Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 4/5.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the enolase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.11" evidence="3"/>
    <dbReference type="EMBL" id="LUGH01000093">
        <property type="protein sequence ID" value="OBZ89485.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NKA6"/>
    <dbReference type="FunCoup" id="A0A1C7NKA6">
        <property type="interactions" value="452"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NKA6"/>
    <dbReference type="InParanoid" id="A0A1C7NKA6"/>
    <dbReference type="OrthoDB" id="1739814at2759"/>
    <dbReference type="UniPathway" id="UPA00109">
        <property type="reaction ID" value="UER00187"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000015">
        <property type="term" value="C:phosphopyruvate hydratase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004634">
        <property type="term" value="F:phosphopyruvate hydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006096">
        <property type="term" value="P:glycolytic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd03313">
        <property type="entry name" value="enolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.390.10:FF:000001">
        <property type="entry name" value="Enolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.120:FF:000002">
        <property type="entry name" value="Enolase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.120">
        <property type="entry name" value="Enolase-like C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.390.10">
        <property type="entry name" value="Enolase-like, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00318">
        <property type="entry name" value="Enolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000941">
        <property type="entry name" value="Enolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036849">
        <property type="entry name" value="Enolase-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029017">
        <property type="entry name" value="Enolase-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020810">
        <property type="entry name" value="Enolase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020809">
        <property type="entry name" value="Enolase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020811">
        <property type="entry name" value="Enolase_N"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01060">
        <property type="entry name" value="eno"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11902">
        <property type="entry name" value="ENOLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11902:SF1">
        <property type="entry name" value="ENOLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00113">
        <property type="entry name" value="Enolase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03952">
        <property type="entry name" value="Enolase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001400">
        <property type="entry name" value="Enolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00148">
        <property type="entry name" value="ENOLASE"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00002">
        <property type="entry name" value="enolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG00178">
        <property type="entry name" value="enolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00001">
        <property type="entry name" value="Enolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01192">
        <property type="entry name" value="Enolase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01193">
        <property type="entry name" value="Enolase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51604">
        <property type="entry name" value="Enolase C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54826">
        <property type="entry name" value="Enolase N-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00164">
        <property type="entry name" value="ENOLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="6" id="KW-0456">Lyase</keyword>
    <keyword evidence="4 10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Enolase N-terminal" evidence="12">
        <location>
            <begin position="4"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="domain" description="Enolase C-terminal TIM barrel" evidence="11">
        <location>
            <begin position="144"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="8">
        <location>
            <position position="212"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="8">
        <location>
            <position position="346"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="160"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="169"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="247"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="296"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="296"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="321"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="321"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="373"/>
            <end position="376"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="397"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012058"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00048333"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR001400-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR001400-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR001400-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM01192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM01193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="OBZ89485.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="438" mass="47169" checksum="2871B838F38D6E67" modified="2016-11-30" version="1">MSTVSKVHARQIFDSRGNPTVEVEVTTAKGVFRAAVPSGASTGIHEAIELRDGDKSSYMGKGVQKAVANVIDVISPALVEAKIPVTEQKAIDEFLIKLDGTANKGKLGANAILGVSLAVAKAAAADKGVPLYVHFADLSGSKKPFVLPVPAFNVINGGSHAGNKLAMQEFMILPTGAKSFREAMKIGSEVYHNLQKVIKEKYGLDATNVGDEGGFAPNIQNNEEGLELLVTAIEKAGYTGKVKIGMDVAASEFFKEDKYDLDFKNPDSDKSKWLDGKELSALYKSFAEKYPIVSIEDAFDQDDWENWAHLKESSEFQLVGDDLLVTNPARIATAVEKKACNALLLKVNQIGTVTESIQAALDSQAAGWGVMVSHRSGETEDTTIADLVVGLRTGQIKTGAPCRSERLAKYNQLLRIEEELGEGNSIYAGEHFRTAHNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NKC3</accession>
    <name>A0A1C7NKC3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Charged multivesicular body protein 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">chmp3</name>
        <name evidence="2" type="ORF">A0J61_02498</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000095">
        <property type="protein sequence ID" value="OBZ89458.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NKC3"/>
    <dbReference type="FunCoup" id="A0A1C7NKC3">
        <property type="interactions" value="279"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NKC3"/>
    <dbReference type="InParanoid" id="A0A1C7NKC3"/>
    <dbReference type="OrthoDB" id="2329734at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043328">
        <property type="term" value="P:protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.1230">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005024">
        <property type="entry name" value="Snf7_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10476">
        <property type="entry name" value="CHARGED MULTIVESICULAR BODY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03357">
        <property type="entry name" value="Snf7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="183"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="195"/>
            <end position="207"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ89458.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="220" mass="24986" checksum="CAB968F261540514" modified="2016-11-30" version="1">MSSAIQRFFGKKTPDEMVKKWRQEIRAQQRGIDRQIRAIDTEEIKVKRSIKQVAKKGDVKNCKMLAKELIRSQRHKDRLYTSKAQMNSIIMQLEHQLATLKVAGSLQKSGEVMKLVNQLSRLPEISQTMQQMSMEMTKAGLMEEMIGDTMDMMDDDDIEEAADEEVNNVLYQITDGMLGEAGSVGATLESRTAVEEPESESEEEGPELDMMQKRLQALKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NKC6</accession>
    <name>A0A1C7NKC6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="13">NFX1-type zinc finger-containing protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">Znfx1_0</name>
        <name evidence="13" type="ORF">A0J61_02694</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the DNA2/NAM7 helicase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000105">
        <property type="protein sequence ID" value="OBZ89249.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NKC6"/>
    <dbReference type="FunCoup" id="A0A1C7NKC6">
        <property type="interactions" value="3"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NKC6"/>
    <dbReference type="InParanoid" id="A0A1C7NKC6"/>
    <dbReference type="OrthoDB" id="409395at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005694">
        <property type="term" value="C:chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031380">
        <property type="term" value="C:nuclear RNA-directed RNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031048">
        <property type="term" value="P:regulatory ncRNA-mediated heterochromatin formation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06008">
        <property type="entry name" value="NF-X1-zinc-finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18808">
        <property type="entry name" value="SF1_C_Upf1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000326">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045055">
        <property type="entry name" value="DNA2/NAM7-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041679">
        <property type="entry name" value="DNA2/NAM7-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041677">
        <property type="entry name" value="DNA2/NAM7_AAA_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047187">
        <property type="entry name" value="SF1_C_Upf1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000967">
        <property type="entry name" value="Znf_NFX1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057373">
        <property type="entry name" value="ZNFX1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10887">
        <property type="entry name" value="DNA2/NAM7 HELICASE FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10887:SF341">
        <property type="entry name" value="NFX1-TYPE ZINC FINGER-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13086">
        <property type="entry name" value="AAA_11"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13087">
        <property type="entry name" value="AAA_12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25396">
        <property type="entry name" value="ZNFX1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00438">
        <property type="entry name" value="ZnF_NFX"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-0347">Helicase</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="8" id="KW-0862">Zinc</keyword>
    <keyword evidence="5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="NF-X1-type" evidence="12">
        <location>
            <begin position="1186"/>
            <end position="1206"/>
        </location>
    </feature>
    <feature type="domain" description="NF-X1-type" evidence="12">
        <location>
            <begin position="1214"/>
            <end position="1231"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="38"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="577"/>
            <end position="596"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="602"/>
            <end position="643"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="10">
        <location>
            <begin position="822"/>
            <end position="849"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="579"/>
            <end position="588"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM00438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="OBZ89249.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="1272" mass="146008" checksum="8B1DA0A7DE3F87B0" modified="2016-11-30" version="1">MSRKGGSRQHWNNIDWDAAFSTGPAVVNATLNSITNEFEVSRPPPSTRSRFDFSSNQPSTSWINSAQAGWNTNATEGSPVWSNKDVQQEDEHHNKFSTKDFTAETTTFRLNFDIDETPTFSKVTDYSSFRKQNVVPDFDDVIINPELKDPEEWANVTHRDPFPEVPVNRIKQPYDSVEQYLYTHFELMRQDFLIPLQNAVKSYKEVYHATKDADDVGVAMENSSSYQKPYRLYEHVGLNAIVFGIKQPLYRISFRLPYYVRVNWAQSKRLMPGTLVLLSRDHFEKDLKIATIVERGEEPLRGPGRFEYLLDLYLERDNEDQPLGFGDPSLSTEDTYVMLEATDGYFEAYRHVLNVLQKTSNDGLPFSQYLVELSNNVLVPHYAARKRYYDINVRNNGRGKDQWAIDIFNEWPRYPIGMDDTQTDALRTILSHNLSIVQGPPGTGKTYVGTYAMRILLNNFGGGTGPIVCICQTNHALDQFLEHIYGHSDKIVRVGGRSKSDILKENTLYELKKAHERPRGIGRLYRARDKVSQEIKSLIVEMYEQPCVTIEYIESIKGLRDRQIGSLRYILTKEKNRKNTPNTTSSAANRDDSDDDWEISSVQPVAAPKPPPVPTNKNQRERFSRNPKASPKTNARNDWAGGNPNHIVEIKEKEPNPVEIWLQEAIEYIDNSGVNTSLAEEMKQNFLDQDKGLVIEEDTEERDLIEEEEFLDVQQAFRGEELDTRNKSPYIQIGRAYQKQTETAPGENPGRKIINYNKSKPATTFNTQAFSFFDDNKSNDINDEEEEHTKYSLERWRREDDVSMWPLPVRLKAHKEWADRRRNELQSKLNACMRQYQEISDEIRRLTAAYEAKICRANYVVGMTSTAAAKYHDLLQEIRPKIMVVEEAAEMLESHIITALTDSLEHLILIGDHQQLRPSTAVHELSENHALGVSLFERLVMNQFPFTRLSHQRRMRPEIRALINPIYKDPPLNDHPDVYKYPPIRGMEQSMFFLAHNQDETHMNESASKINEHEAVMAAKLSVYLMLQGYKAEEITIITMYSGQKTMIKRALREERRAHVDPEPILVSSVDGYQGEENKIIILSLVRSNANGQIGFLKVANRVCVSLSRAQHGLYILGNARLLCERSDLWNEIVGNIEDNEEQMIGTKITLKCEKHQTRTEVQWPVDFVEVEGGGCNQICGETLPCGHKCTLKCHSYDHEDYRCKLKCEKVLPCKHVCIRRCCEDCKPCIAPISVRLPCGDMIDAECHVIRNMALNPKGKTCPQCNAPLDNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NKH8</accession>
    <name>A0A1C7NKH8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Solute carrier family 41 member 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">SLC41A2_1</name>
        <name evidence="12" type="ORF">A0J61_02315</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SLC41A transporter family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000085">
        <property type="protein sequence ID" value="OBZ89632.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NKH8"/>
    <dbReference type="InParanoid" id="A0A1C7NKH8"/>
    <dbReference type="OrthoDB" id="666972at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008324">
        <property type="term" value="F:monoatomic cation transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.357.20:FF:000001">
        <property type="entry name" value="Solute carrier family 41 member 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.357.20">
        <property type="entry name" value="SLC41 divalent cation transporters, integral membrane domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006667">
        <property type="entry name" value="SLC41_membr_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036739">
        <property type="entry name" value="SLC41_membr_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045349">
        <property type="entry name" value="SLC41A1-3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16228">
        <property type="entry name" value="DIVALENT CATION TRANSPORTER SOLUTE CARRIER FAMILY 41"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16228:SF7">
        <property type="entry name" value="SLC41A_MGTE INTEGRAL MEMBRANE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01769">
        <property type="entry name" value="MgtE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161093">
        <property type="entry name" value="MgtE membrane domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0406">Ion transport</keyword>
    <keyword evidence="5" id="KW-0460">Magnesium</keyword>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="69"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="148"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="184"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="254"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="286"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="316"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="355"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="380"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="421"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="domain" description="SLC41A/MgtE integral membrane" evidence="11">
        <location>
            <begin position="106"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="domain" description="SLC41A/MgtE integral membrane" evidence="11">
        <location>
            <begin position="318"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="16"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="9">
        <location>
            <begin position="24"/>
            <end position="33"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009749"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF01769"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="OBZ89632.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="457" mass="50399" checksum="1EDA0A6471AB59DF" modified="2016-11-30" version="1">MAPTYQHVQTEDIELSTTGDHLKVPKRPARHTRSGSNSSFIHFRAPQPITEEDHHSSNNNKNSQLASQALPSLVICVIGLIFAGWMMDVYQHWKVFTQVSELFILVPVLLNLKGNLEMNLAARFSTSANLGDLDQPATRNALVWGNMALIQVQALISGSIAGLFSVFLGTILHPEQTTTVSESMLVIASSMVSASVSSFVLGLFMCVLIIISRILKIDPDNIACPMASSLGDVVTLGILAECANLLLIHMETSLSTWLLLSMFVSIPFFGLSVWRNHHVKDLLLSGWSPIILAMLISSGAGLVLERYVEKFNGLAMLTPILCGLAGNLGSIYASRISTCLHRGAQEQFKLVEHTLLLMNVPIQLLFLMIVWVLDIGHLDFTIAFIITYFIVSMICTFSALKMGKSMTLTFWKYKYDPDNYVLPYLTAIVDVICTSLLVISFSWLTSNGYASLGVHDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NMH1</accession>
    <name>A0A1C7NMH1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">RNA polymerase II subunit A C-terminal domain phosphatase</fullName>
            <ecNumber evidence="6">3.1.3.16</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">fcp1_1</name>
        <name evidence="10" type="ORF">A0J61_03486</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">This promotes the activity of RNA polymerase II.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>O-phospho-L-seryl-[protein] + H2O = L-seryl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:20629"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="EC" id="3.1.3.16"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:47004"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="EC" id="3.1.3.16"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.16" evidence="6"/>
    <dbReference type="EMBL" id="LUGH01000151">
        <property type="protein sequence ID" value="OBZ88464.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NMH1"/>
    <dbReference type="STRING" id="101091.A0A1C7NMH1"/>
    <dbReference type="InParanoid" id="A0A1C7NMH1"/>
    <dbReference type="OrthoDB" id="10249888at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008420">
        <property type="term" value="F:RNA polymerase II CTD heptapeptide repeat phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd17729">
        <property type="entry name" value="BRCT_CTDP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd07521">
        <property type="entry name" value="HAD_FCP1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10190">
        <property type="entry name" value="BRCT domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.10">
        <property type="entry name" value="S15/NS1, RNA-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001357">
        <property type="entry name" value="BRCT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036420">
        <property type="entry name" value="BRCT_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039189">
        <property type="entry name" value="Fcp1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004274">
        <property type="entry name" value="FCP1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011947">
        <property type="entry name" value="FCP1_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02250">
        <property type="entry name" value="FCP1_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23081">
        <property type="entry name" value="RNA POLYMERASE II CTD PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23081:SF36">
        <property type="entry name" value="RNA POLYMERASE II SUBUNIT A C-TERMINAL DOMAIN PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03031">
        <property type="entry name" value="NIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12738">
        <property type="entry name" value="PTCB-BRCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00292">
        <property type="entry name" value="BRCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00577">
        <property type="entry name" value="CPDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52113">
        <property type="entry name" value="BRCT domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50172">
        <property type="entry name" value="BRCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50969">
        <property type="entry name" value="FCP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FCP1 homology" evidence="9">
        <location>
            <begin position="58"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="domain" description="BRCT" evidence="8">
        <location>
            <begin position="259"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="361"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="405"/>
            <end position="505"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="405"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="455"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="467"/>
            <end position="486"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00047761"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00048336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU366066"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50969"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OBZ88464.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="505" mass="57252" checksum="10504A1239EED499" modified="2016-11-30" version="1">METCKHQIQYNGLCAVCGTLLEAKPTEAYANMGYDITGLSVSREEAEKLESENAKRLLKARKLSLILDLDQTIIHASCDPKYEKHTQESNIRQFVLQNNTVYYVKLRPGLEEFLKELDKLYELHIYTMGNRDYADAITKEIDPTGSIFKERVLSRDESGSVTQKKLQRLFPCDISMVVVLDDRSDVWNSAPNLIRIKPYEFFVDRKNSITQAVAEKNDDPDWGADNELMVVLKILQEVHHKFYSIPSEQADVTCIIPNMKKQVLANIKITFSDKILSTQHIKDPTLSWIWQMATSFGATCSVDLTGKTTHLIAINNSRNKVKAAREYGHNIHIVTPAWLLDSTARWQVQPEENYAVVDVDRSERTPLDSESVPSEMPTPQEKELENINWDEANREVEDFINESGIDDVWDDTDSDTIDIPWTTQPLWKRKRESGGESGGDGSEDEESSLSGSFLARRKLRATKRGKSQLSKVTTAPSSRCTSGNTTDNEDSSLDAFVGMLDRELE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NMH5</accession>
    <name>A0A1C7NMH5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">SH3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">A0J61_01643</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000055">
        <property type="protein sequence ID" value="OBZ90297.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NMH5"/>
    <dbReference type="STRING" id="101091.A0A1C7NMH5"/>
    <dbReference type="InParanoid" id="A0A1C7NMH5"/>
    <dbReference type="OrthoDB" id="196165at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051286">
        <property type="term" value="C:cell tip"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015630">
        <property type="term" value="C:microtubule cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030950">
        <property type="term" value="P:establishment or maintenance of actin cytoskeleton polarity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008104">
        <property type="term" value="P:intracellular protein localization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.40">
        <property type="entry name" value="SH3 Domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053039">
        <property type="entry name" value="Polarity_Bud-Selection_Reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036028">
        <property type="entry name" value="SH3-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001452">
        <property type="entry name" value="SH3_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47775">
        <property type="entry name" value="BUD SITE SELECTION PROTEIN 14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47775:SF1">
        <property type="entry name" value="BUD SITE SELECTION PROTEIN 14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00018">
        <property type="entry name" value="SH3_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00326">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50044">
        <property type="entry name" value="SH3-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50002">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0728">SH3 domain</keyword>
    <feature type="domain" description="SH3" evidence="4">
        <location>
            <begin position="77"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="205"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="339"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="733"/>
            <end position="791"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="214"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="351"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="388"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="782"/>
            <end position="791"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OBZ90297.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="887" mass="101309" checksum="27A59F82CDAE99FE" modified="2016-11-30" version="1">MPTLLKDNRRLTGYRGDADYNNHQSLYDDDMDDYQDYHMTGDDDVYEEYDEDLDDDQHIQEDHDDTGSELSIPDPNIDFNMVYALHTFAATVEGQASVVRGDALTLLDDSNSYWWLIKVLKTAEVGYIPAENIETPHERLARLNSHRNIELTRRDIQDAFPAPPSNKPKKTKRVTLAKGVQFQSQIIYGSSDDEDDNFEAEFEQWDERMRSDQSDTDDMISEDESDDHYQYYSGQEIEQPIDMYTANYSQMNSNPNAVQNDIHPYQNGHDDSRPIDADSDIINDTFNPRLSKELEDETIKISLTPNIARGVDENPRHSDNNVQSKLRKAAKLERILNAAAAASSSSTEPYLQERRGSKDKDQKKEKSSIRKFFSRKDSTKDNKKNKKQQQQQNDHTLERQISIESASISSQSTGAISIERDRLGSTDSNSAQHYQHQPYLPVQLKINAGNITDFGELPYKMANVLPSTTATELIHQVIQHDPNQEPMGEHAYNDYHLIVRTLGGDEFILVPSDKPLEIFNSLTSHLNTPMPSLRKARRISALMGSDSSHIGGPSQHAPSLDEEVQFYLYSKTKRTDEGEIQIKVCLTEETRVDKSIKIGSHVLIKDAIPILLEKFHILNGIVAGIEDISGLRLDGNDDVVKYRLMIHQNHQERFLELDEKLLDVFGEQVPTIHYRRHSNPDRASMTVNINPPHPDETFFILKRVDQPKPIAIIRQEKGEKIEIQANNEKELIEQPPEHRPRRPLIRQDTPMPVRENTPTGGFEDTPLPNRHRIASPEPEPVLSNSPDSENDLMSQLDEVIDTLAPSPTQKRSRQEVAESMLFCNDFGMNDMMVIIRGAAQKMETVSSNKQQAIRSEISDIFRDPQSRLEQLEKELDRLMSEAVKVYQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NMJ5</accession>
    <name>A0A1C7NMJ5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Sorting nexin-4</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Autophagy-related protein 24</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="primary">SNX4_0</name>
        <name evidence="13" type="ORF">A0J61_01665</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the sorting nexin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000055">
        <property type="protein sequence ID" value="OBZ90307.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NMJ5"/>
    <dbReference type="FunCoup" id="A0A1C7NMJ5">
        <property type="interactions" value="223"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NMJ5"/>
    <dbReference type="InParanoid" id="A0A1C7NMJ5"/>
    <dbReference type="OrthoDB" id="205639at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005769">
        <property type="term" value="C:early endosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000407">
        <property type="term" value="C:phagophore assembly site"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035091">
        <property type="term" value="F:phosphatidylinositol binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000422">
        <property type="term" value="P:autophagy of mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032456">
        <property type="term" value="P:endocytic recycling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034727">
        <property type="term" value="P:piecemeal microautophagy of the nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061709">
        <property type="term" value="P:reticulophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.60">
        <property type="entry name" value="Arfaptin homology (AH) domain/BAR domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1520.10">
        <property type="entry name" value="Phox-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027267">
        <property type="entry name" value="AH/BAR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001683">
        <property type="entry name" value="PX_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036871">
        <property type="entry name" value="PX_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015404">
        <property type="entry name" value="Vps5_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45949">
        <property type="entry name" value="SORTING NEXIN-4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45949:SF2">
        <property type="entry name" value="SORTING NEXIN-4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00787">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09325">
        <property type="entry name" value="Vps5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00312">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64268">
        <property type="entry name" value="PX domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50195">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0446">Lipid-binding</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="domain" description="PX" evidence="12">
        <location>
            <begin position="106"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="62"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="10">
        <location>
            <begin position="254"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="77"/>
            <end position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00040748"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00041273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="OBZ90307.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="500" mass="58029" checksum="9D8362BF1633FE75" modified="2016-11-30" version="1">MSQLTDEQFEAQWNSVDQLDSPALLDPLNHDNQPAILTSHSYISDSSHVDIDISDDRHYPSNPLFLDEDNTHHNNVSSSSSSSSSSSSSSSSNESITEHKREPIVLNKKVFVTDPRKVTEQTSTFITYLVQSNRKQVRRRFQDFVWLHNVLYNHFPACFVPPLPDKHRLEYVKGDRFSTEFIEKRRISLERFIQRIARHPVLGRADFFIMFLESSEFNDASARASREGQETMIDTIGDSLLNAFSKIRKPDPRFVEMKERSDRMEENLDMLQKTLLRTTKRTQDLYQDYQEFTSSTRGLAQIEPSFEKDLAIFADGLEQYTTHLSKVATHESQWQIEVHDYMAYFHAIKDVLKLRDQKQLDFEELSDYLTATIDERANLVRGKKKLSGHGNLAMTGSSVANFITGKLNEVRGADTEKIKREKVLKLDERVRELQEAIEQTHQVTTAFSDQVRKEDAFFNQNRQVEIFDSLKSYTDAKVDFYRDSVQVWRDVVQKLENNNV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NMR8</accession>
    <name>A0A1C7NMR8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">SCF E3 ubiquitin ligase complex F-box protein grrA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">grrA_1</name>
        <name evidence="2" type="ORF">A0J61_02169</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000078">
        <property type="protein sequence ID" value="OBZ89776.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NMR8"/>
    <dbReference type="FunCoup" id="A0A1C7NMR8">
        <property type="interactions" value="439"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NMR8"/>
    <dbReference type="InParanoid" id="A0A1C7NMR8"/>
    <dbReference type="OrthoDB" id="10257471at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019005">
        <property type="term" value="C:SCF ubiquitin ligase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031146">
        <property type="term" value="P:SCF-dependent proteasomal ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057207">
        <property type="entry name" value="FBXL15_LRR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006553">
        <property type="entry name" value="Leu-rich_rpt_Cys-con_subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13318">
        <property type="entry name" value="PARTNER OF PAIRED, ISOFORM B-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25372">
        <property type="entry name" value="DUF7885"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12937">
        <property type="entry name" value="F-box-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00256">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00367">
        <property type="entry name" value="LRR_CC"/>
        <property type="match status" value="11"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0436">Ligase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="1">
        <location>
            <begin position="12"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ89776.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="516" mass="58640" checksum="7C96A1D00A7D2E64" modified="2016-11-30" version="1">MTNLLLLQKPHSYGYSNIPSEILLSILSRLDSTHDLLSCAQVCKLWSYFATELLWYKPNLEVLKSSHKWTMFFSIIQAKSTLFPYALFVRRINLSPLSLVIEDLHIMALRYCKRLERLTLAGCSKLTDIGLCTLIEDVGAALISIDLSDVDQVTDKTIQHTASNCPQLQGINLSMSKPQHGITDASIRQLAYSCNHLRRVRFNRCVQITRESIVPLVIYCPRLMEIDLTNCAVDDTLLTSIFEHSHELKELRIGQADLAHTALTETPFCLAIQQPNSFQQLRFIDLTNITILTDQSLARLIHAAPKIRNLILNRCSSITDEGALTITQLGRYLRCLHLGHCPLLTDRSISRIVTSCSHIRYLDLASCTQITDQSVLEIAKSLSRLRRIGLVKCDRLTDISLEALVYYHADIHDSLERIHLSYCTQLSTKGVAKLLNVCSRLNHLSLTHVPSFLRNDLKAFCRAPPKGLTELQNQVFCVFSGDAIGQLRDHLNRIYKEDLEVLHPLKYAEEYQRRFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NMT0</accession>
    <name>A0A1C7NMT0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Meiotically up-regulated gene 60 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">mug60</name>
        <name evidence="4" type="ORF">A0J61_01627</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000054">
        <property type="protein sequence ID" value="OBZ90328.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NMT0"/>
    <dbReference type="STRING" id="101091.A0A1C7NMT0"/>
    <dbReference type="InParanoid" id="A0A1C7NMT0"/>
    <dbReference type="OrthoDB" id="271862at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd22453">
        <property type="entry name" value="KH-I_MUG60_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1370.10">
        <property type="entry name" value="K Homology domain, type 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004087">
        <property type="entry name" value="KH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004088">
        <property type="entry name" value="KH_dom_type_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036612">
        <property type="entry name" value="KH_dom_type_1_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056553">
        <property type="entry name" value="KH_Mug60-KHD4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00013">
        <property type="entry name" value="KH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24563">
        <property type="entry name" value="KH_Mug60-KHD4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00322">
        <property type="entry name" value="KH"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54791">
        <property type="entry name" value="Eukaryotic type KH-domain (KH-domain type I)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50084">
        <property type="entry name" value="KH_TYPE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="K Homology" evidence="3">
        <location>
            <begin position="169"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="domain" description="K Homology" evidence="3">
        <location>
            <begin position="412"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="domain" description="K Homology" evidence="3">
        <location>
            <begin position="483"/>
            <end position="563"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="789"/>
            <end position="815"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="933"/>
            <end position="953"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="983"/>
            <end position="1045"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1079"/>
            <end position="1107"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1188"/>
            <end position="1220"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="937"/>
            <end position="953"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="997"/>
            <end position="1021"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1022"/>
            <end position="1032"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1090"/>
            <end position="1105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1188"/>
            <end position="1197"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1200"/>
            <end position="1212"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00322"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OBZ90328.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="1220" mass="135836" checksum="F4296775DC6F5DE8" modified="2016-11-30" version="1">MAALSFCYAPPLSGQYDQYVKQDEALIISDLQDKCQKIMTARGCQISVMTTKSTKQLGSSTNCPTEFNISMTGSPQALMEARGDLLSHCPLEIKLKLRIPPNPNLSLLTDHFGQLENEFEVKITLVPEQPNLSSLVSDNTATIEIVGHPTKVEQCRVRVLVAIDEIMYSFKTEIVRMPLKLQYLICGRKRAGLLPIIEETATNIYFSSPFIHTELADNTLNTELIDQQEHPTDPPIYITGEQVHVLRVKDMLNKLAVQKAKSMYHKDTALYARKIDWLLLHRRDELRKIMHDNGAYIEFPSLGSGDNRVTVYAENRVNAERTLRALNFQACTIYEACFYFNNNDGAIYDPTGSHAFFESTSNISNLVSQLSQVSGSEVIYKTDPGCIEVLGAERAIRNVYQRLQEMQFLQVFHQYTIFRVESSNDQRDFISGKKNGKINKIMKTSGAKIRFVTFINDYNFVIEVESTSFTKALDGLTLLQEELPAEISFYVPESYHKRIIGVGGKNIQRIMKKYGVYVKFSNTEEFASLGGYYNNEDNVVARTPMKNQINLDNLRHAVMELIHPKDRDYIAEIVLIPFQLHRSLIHDYQDGFINEELTKKTNTHVLWPDAELASNTVELLGPEAHMAVAIKMLESIVPESYDLHVPSSQAFYKAIQSESFQEQVVNILDHEYGITVKSSLLMCDSDENLSNSETISNATDQTNQLSNQSGFIRLSTTKDKIPSVLKDALATVIDFLKSQQVPLYEKTSADALVSLVEKKCQSTSKKSNLSASSSSSLLDNSLLNKHQPTQALTSSVAGAPTGITGSAGTSIMPPPTITIPMSAMGRHEPSNDPIYSMGGNMAQPIIPQAYPFYHFQANKDIPLDSSHWIPVNSPNNKNNTSTNAAIVAAAAQMQAQMQAQLQTQIQAQMQAQQQQQQQQQQQQQQQQQQQQQQQQQPTASASTTSLQSNGSDNNLRAIFDAPLELTDQERVVLSNYRYQRMSMPPPPSASSSFGFPQTMSSSTPASDIWSTPTSQIANNRRSTGGFSSGSMTSPPPNSRRAAGASYASTVANDNMKMRRYNDNNPNTFYPGMGGIGSSKEFNPYNDIPHSSSSTTTNSSLKSSQSMPEPMLEAHFNAGRPPFQTSPSFHANQAQAFSQLNMNYRVANKSTNNNTNASLISQNTTPQHEQNQFFMNPTEVNAVQNVFEKLSNQSTGSSGYDPRRQHDQDDKGSRAPPGIDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NMW4</accession>
    <name>A0A1C7NMW4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="15">Putative dipeptidyl-aminopeptidase B</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="15" type="primary">dapB_1</name>
        <name evidence="15" type="ORF">A0J61_01660</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Vacuole membrane</location>
            <topology evidence="1">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peptidase S9B family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000055">
        <property type="protein sequence ID" value="OBZ90310.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NMW4"/>
    <dbReference type="FunCoup" id="A0A1C7NMW4">
        <property type="interactions" value="140"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NMW4"/>
    <dbReference type="InParanoid" id="A0A1C7NMW4"/>
    <dbReference type="OrthoDB" id="16520at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005774">
        <property type="term" value="C:vacuolar membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004177">
        <property type="term" value="F:aminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008239">
        <property type="term" value="F:dipeptidyl-peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1820:FF:000003">
        <property type="entry name" value="Dipeptidyl peptidase 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.140.10.30">
        <property type="entry name" value="Dipeptidylpeptidase IV, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002471">
        <property type="entry name" value="Pept_S9_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001375">
        <property type="entry name" value="Peptidase_S9_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002469">
        <property type="entry name" value="Peptidase_S9B_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050278">
        <property type="entry name" value="Serine_Prot_S9B/DPPIV"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11731:SF200">
        <property type="entry name" value="DIPEPTIDYL PEPTIDASE 10, ISOFORM B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11731">
        <property type="entry name" value="PROTEASE FAMILY S9B,C DIPEPTIDYL-PEPTIDASE IV-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00930">
        <property type="entry name" value="DPPIV_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00326">
        <property type="entry name" value="Peptidase_S9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82171">
        <property type="entry name" value="DPP6 N-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00708">
        <property type="entry name" value="PRO_ENDOPEP_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 15" id="KW-0031">Aminopeptidase</keyword>
    <keyword evidence="11" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0645">Protease</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0720">Serine protease</keyword>
    <keyword evidence="8" id="KW-0735">Signal-anchor</keyword>
    <keyword evidence="5 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 12" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="64"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="domain" description="Dipeptidylpeptidase IV N-terminal" evidence="14">
        <location>
            <begin position="183"/>
            <end position="578"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S9 prolyl oligopeptidase catalytic" evidence="13">
        <location>
            <begin position="659"/>
            <end position="862"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF00326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF00930"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="OBZ90310.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="884" mass="100772" checksum="CB78FE940A8C971F" modified="2016-11-30" version="1">MAFKSYLTHSDEENRDTPTQHLLNATAQQQTGSDDLEDEDLCYYSDEKTVFDDENAYHSGKKGVNWVCVGLVSVLGLAWLLWTVSMAQLFTIFTPSTDKINDGSHSNKRFQFEDVFNSSFSPKRTNLVWVENDPRDGIYTYRDPNSNDILLESIEDRKSQVFVQEKDLKIDGNLLNVQSFELSHDAEYLLFKTNVTAKWRHSALFNAYLFHVSTKKITPLSSATTVNSEPKISYAVWSPTGHQLAYVMNNDIYITDLVKHQRITFDGSKTIFNGIPDWVYEEEVLASDFALWWAPDSSHLAYLKLDETKVPEYHVQMFTSNYNASYPKEDNIKYPKAGAPNPLVSLHVYSLSSNKTITATSTTESSNSINILKDNQYNAQDFKEDDRLIVDVAWATDSHTHLLFKQTNRIQDQQVTNMIQIDGAHLENSTIKSVHEYKPTDGGWIDVSQSIVHLPSSYKDTQSISYLDILDNNEGFAHLAIITVTKEKVKTTWLTNGSWEVVSGTVQVDPKRQLIHFVSTERSPHERHLYRLSLKDRHSSKTCITCPSDPEEHAYYTATFSPQSGYYVLNYEGPDVPTTVVRKVDDDNFSAVLQNNTALKSLLQDYDLPKMHMKTISSGGVEMTAMEVLPADFDAKKKYPVLFHVYGGPGSQLVSYRFELSWQTFVASQLGFTVVTVDGRGTGFQGRKYRMGVRGRLGELETIDQVNAAKHWAQLDYVDEYRMAIWGWSYGGYMTSKVIESNDGVFSTGMAVAPVTDWRYYDSVYTERYMKTPELNPEGYTHSAVDKMEGFKNARYLLAHGTGDDNVHFQHTAVLVDKLTLNDIHNYRVQIYPDSNHAIRHHNANKNVYYLLTEYLLESFGGHEYQHIYRESHGKFSGPLPTED</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NN99</accession>
    <name>A0A1C7NN99_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">NmrA-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_01339</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000041">
        <property type="protein sequence ID" value="OBZ90611.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NN99"/>
    <dbReference type="STRING" id="101091.A0A1C7NN99"/>
    <dbReference type="InParanoid" id="A0A1C7NN99"/>
    <dbReference type="OrthoDB" id="10254221at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051604">
        <property type="entry name" value="Ergot_Alk_Oxidoreductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008030">
        <property type="entry name" value="NmrA-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43162">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43162:SF1">
        <property type="entry name" value="PRESTALK A DIFFERENTIATION PROTEIN A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05368">
        <property type="entry name" value="NmrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NmrA-like" evidence="1">
        <location>
            <begin position="43"/>
            <end position="227"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF05368"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ90611.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="360" mass="42402" checksum="BC03C549D9448E44" modified="2016-11-30" version="1">MSSEKQVCCITNGDSLLGFAIASRFAVALFGGESNVQGGKPELRILCRTRSGYGLTKLEKMGCKIMEVDYMNEEKLQMALKDCSACLLVPEHSGNRLKEAECLLQCAKKMKVEHMTMMSFVGVDRMQEKRSESSEFHHMMEFHKIEKMVQECFQGQMHCIIRCAMFYQMFYYLAPQMQKENVMCLPVKKDAKWPGVDLNDICEGVYCLAKKQHERVRQHQAGSGEEIFNKRMYNFMHQPMSTQHMTQEIAHGLNCKELHFKEISEDELMEYMMKVKDDKKFQERPDENNDFKKGKDGYWSFPLNKFITEHKIRCIMEYFRMANKGCLEQHHEDLQKVLERNPHSLKQYFEVNRDQFKRFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NNU0</accession>
    <name>A0A1C7NNU0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_01153</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000033">
        <property type="protein sequence ID" value="OBZ90803.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NNU0"/>
    <dbReference type="InParanoid" id="A0A1C7NNU0"/>
    <dbReference type="OrthoDB" id="2366767at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ90803.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="142" mass="15970" checksum="CFD3283E42B619C9" modified="2016-11-30" version="1">MNNTKSLKRKLTTKNVRFAAEITVLETYSADEYDRSNFFSSPTVYKINPRLKPPQLTLDIPCLIQDNEDIVSSAENSPNSPPILALVNHYFPPQQRKKKKVQLSINTSICSDPLFFSGLSTNYKNDTIETDANDFLVPASAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NNU3</accession>
    <name>A0A1C7NNU3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Kinesin-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">Kif21a_0</name>
        <name evidence="11" type="ORF">A0J61_01134</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6 7">Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000033">
        <property type="protein sequence ID" value="OBZ90792.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="FunCoup" id="A0A1C7NNU3">
        <property type="interactions" value="253"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NNU3"/>
    <dbReference type="InParanoid" id="A0A1C7NNU3"/>
    <dbReference type="OrthoDB" id="3176171at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005875">
        <property type="term" value="C:microtubule associated complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008017">
        <property type="term" value="F:microtubule binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003777">
        <property type="term" value="F:microtubule motor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007018">
        <property type="term" value="P:microtubule-based movement"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007052">
        <property type="term" value="P:mitotic spindle organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051231">
        <property type="term" value="P:spindle elongation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.850.10">
        <property type="entry name" value="Kinesin motor domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027640">
        <property type="entry name" value="Kinesin-like_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019821">
        <property type="entry name" value="Kinesin_motor_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001752">
        <property type="entry name" value="Kinesin_motor_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036961">
        <property type="entry name" value="Kinesin_motor_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47969">
        <property type="entry name" value="CHROMOSOME-ASSOCIATED KINESIN KIF4A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47969:SF15">
        <property type="entry name" value="CHROMOSOME-ASSOCIATED KINESIN KIF4A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00225">
        <property type="entry name" value="Kinesin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00380">
        <property type="entry name" value="KINESINHEAVY"/>
    </dbReference>
    <dbReference type="SMART" id="SM00129">
        <property type="entry name" value="KISc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00411">
        <property type="entry name" value="KINESIN_MOTOR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50067">
        <property type="entry name" value="KINESIN_MOTOR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0493">Microtubule</keyword>
    <keyword evidence="6 7" id="KW-0505">Motor protein</keyword>
    <keyword evidence="3 6 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Kinesin motor" evidence="10">
        <location>
            <begin position="20"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="169"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="311"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="502"/>
            <end position="543"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="577"/>
            <end position="611"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="749"/>
            <end position="948"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="169"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="192"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="318"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="508"/>
            <end position="520"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="527"/>
            <end position="540"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="104"/>
            <end position="111"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="non-terminal residue" evidence="11">
        <location>
            <position position="960"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00283"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000394"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50067"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="OBZ90792.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="960" mass="107164" checksum="E3505A20ECD48408" modified="2016-11-30" version="1" fragment="single">MIASTPMSCNSITGSSQSTAVQVALRVRPLTRQDKAQPRFSNSTDSDVIKTFENSVAIIPHQKSFQFDHVFDSSSTQEDVFSAVGSKLVDRFLDGYNVTILAYGQTSSGKTYTMGTALDSQRNSNPEQEGIIPRAMSALFEQIEKSQSPTKSSSIHSGIRRIPSLLSTTPGTSFVSRMSKQPGPSAKLKPASTISRRGSNIPPTSSEPPQNDKATRYTVHVSFIEIYNEELIDLLNPAPAQERSPITIREDAKGHIIWTXLKEIPVKSTNDVLRHXQTGTENRATGSTDMNAKSSRSHAIFSVTLKQEKWVSSGNTASETPSTSRSNSRSVQRQSTLNVKAMIGQMERRNSVTEEKQGEWIVTQSKFHFVDLAGSERLKRTAAEGDRRKEGININAGLSALGNVICALSDPHKKPIHVPYRDSKLTRLLQDSLGGNSTTLMIACVSPAEADLTETANTLKYACRARSIHNKSEKNETEEWMISDNVDYLRQLITKLKSEIKSLKTSSRRTPSPHSSASKSSKTKHVNSSNFRAASSSSSSLTNDSDVCLSYNSSATTQNTAFEAPAFSETCHDQDNSNDTAALLSDLRRQIEELQNELSVTRERNLHVEMELSHLNVKNRSEISSPEEFQHLVEPVIEEYEKSISGLESQLAAAKTALSQSDQVLSVQQAKIAEYLQIQTSESQAIRDLKSRLSAALEREQSSEIYCTELEAKLHKSIEEAQKDQKVLSELREKIIKFKEMDSQTEKYISDLESRLSSSESERAKLSEEVAGLAVNREKDLLSAQALQQKESIEEKLDISEAKCKELEQQLANLREYAKLKETESADNSCRTNELSTLLAQKESEMKAFESKLNEIGQLEDKLSRLRQTHMLEIERLEEALADLKETHQAELLDQKYQEQVKIDKLTEAKHKLEMQMQVQEEQNKKQKEEEIEKLQAAMNALSSVDERQTALIQGLELKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NPJ6</accession>
    <name>A0A1C7NPJ6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DNA damage-binding protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">DDB1_2</name>
        <name evidence="2" type="ORF">A0J61_01104</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000032">
        <property type="protein sequence ID" value="OBZ90829.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NPJ6"/>
    <dbReference type="STRING" id="101091.A0A1C7NPJ6"/>
    <dbReference type="InParanoid" id="A0A1C7NPJ6"/>
    <dbReference type="OrthoDB" id="433457at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.910">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050358">
        <property type="entry name" value="RSE1/DDB1/CFT1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004871">
        <property type="entry name" value="RSE1/DDB1/CPSF1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10644">
        <property type="entry name" value="DNA REPAIR/RNA PROCESSING CPSF FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03178">
        <property type="entry name" value="CPSF_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RSE1/DDB1/CPSF1 C-terminal" evidence="1">
        <location>
            <begin position="69"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03178"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ90829.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="417" mass="46895" checksum="E2357DF277E920CF" modified="2016-11-30" version="1" fragment="single">LSFPDAVALATKDGLIIGQMEEIQKLHITKIPTKDTPRRIAYQEASRTFGLVTERVVSEPYTRSTTTGGFEILDDQSFNVLDRVYFQQFERPTAAISITFENDHNEYYVLATGKETDEYENNSIGRICIFQVTFERKLKLVHQFQTEGMVDSIRSFNGKLIASIHGMLHVFKWESTFGKNGLTSSCSKRLPSIAESISTYNELIIIGDLAYSVVVLSYDPKTDTLTEVAAHEKLKEVVAIEASDDNLYVAAEREGHLFVVERCQDESDEPVLETVSVWHLGDFVRRFRYGSLSMNHGDPDKNPEAPTLIFATANGSIGLIADLSAERFKLLDQMQYNMSRTIKSIGNLSHIDWRSVSIMNRKDDAVNFIDGDLIESFLDLTPQQMQNVVDGVGGGRKLDKSVEDICKVVEELMSLHP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NQ07</accession>
    <name>A0A1C7NQ07_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Cell differentiation protein rcd1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">rcd1</name>
        <name evidence="3" type="ORF">A0J61_02624</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CNOT9 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000101">
        <property type="protein sequence ID" value="OBZ89334.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="FunCoup" id="A0A1C7NQ07">
        <property type="interactions" value="510"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NQ07"/>
    <dbReference type="InParanoid" id="A0A1C7NQ07"/>
    <dbReference type="OrthoDB" id="1183224at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030014">
        <property type="term" value="C:CCR4-NOT complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006402">
        <property type="term" value="P:mRNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.10.10:FF:000014">
        <property type="entry name" value="Cell differentiation protein RCD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007216">
        <property type="entry name" value="CNOT9"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12262">
        <property type="entry name" value="CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04078">
        <property type="entry name" value="Rcd1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="76"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="81"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="92"/>
            <end position="106"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006385"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ89334.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="381" mass="42764" checksum="C07EB26282BA45B6" modified="2016-11-30" version="1">MHPNSHLHQYLQQSSLAGTANPLTAAALQPGTNNMNALSQHFPAMNRNAGANNADPFVYAQMMNNAASQAMPMSTAFAMQPQPPPPPPPPQQQQQQQQQHAQPEQKLQQLDEEKIYGLVLDLLNPSSREQALLDLSKKREQYEDLALVLWYSYGVIPVLLQEIITVYPLLTPPTLSGGASNRVCNALALLQCVANHNETRSLFLQAHIPLYLYPFLNTTSKTRPFEYLRLTSLGVIGALVKNDXXEVISFLLSTEIIPLCLRIMETGSELSKTVAIFVVQKILLDETGLYYICQTYERFYAVATVLHNMVNQLVENQAMRLLKHVIRCYLRLSENPRAREALRQCLPEPLRDSTFHQALKDDIATKRCLGQLLLNLSDGIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NQ77</accession>
    <name>A0A1C7NQ77_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">ENTH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">A0J61_00703</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000017">
        <property type="protein sequence ID" value="OBZ91257.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NQ77"/>
    <dbReference type="FunCoup" id="A0A1C7NQ77">
        <property type="interactions" value="315"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NQ77"/>
    <dbReference type="InParanoid" id="A0A1C7NQ77"/>
    <dbReference type="OrthoDB" id="4033880at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030125">
        <property type="term" value="C:clathrin vesicle coat"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005768">
        <property type="term" value="C:endosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030276">
        <property type="term" value="F:clathrin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005543">
        <property type="term" value="F:phospholipid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006897">
        <property type="term" value="P:endocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006895">
        <property type="term" value="P:Golgi to endosome transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd16992">
        <property type="entry name" value="ENTH_Ent3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.90:FF:000006">
        <property type="entry name" value="Clathrin interactor 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013809">
        <property type="entry name" value="ENTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008942">
        <property type="entry name" value="ENTH_VHS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12276:SF45">
        <property type="entry name" value="CLATHRIN INTERACTOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12276">
        <property type="entry name" value="EPSIN/ENT-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01417">
        <property type="entry name" value="ENTH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00273">
        <property type="entry name" value="ENTH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48464">
        <property type="entry name" value="ENTH/VHS domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50942">
        <property type="entry name" value="ENTH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ENTH" evidence="3">
        <location>
            <begin position="26"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="205"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="272"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="415"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="138"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="241"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="283"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="305"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="415"/>
            <end position="463"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OBZ91257.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="470" mass="51772" checksum="518898A18A473BED" modified="2016-11-30" version="1">MNNFANFNFQIPELWEVRDAFNKVKNVVLNYTEMEAKVHEATNNEAWGASSTLMQEIAQATFHYEYFNEIMPTIYKRFTEKEARQWRQIYKSLVLLEYLVKNGSERVVDDARSHISMIKMMKNFHYIDEKGKDQGINVRNRAKELAELLNDVEAIKAERKKAKKNRNKYTGVGSDGGMSYAGAGIGGSRYEGFGSETGGYSTGGMDSYGSGGYGNDSYDSTRPGRYDEGTTNSSPTLSEEETIRSSAKKEVEPKKAKTAKELNLFDFDEPAVEQKSQVKSNDDDWGDFAGGEENEDDFDDFQSAPIPTTSSAQKTSTINTSNKSNDIFDLLGEENIVTSSQPSPSVQALSFSTLSISSNPTQSSAVNQTQSTANISVNQTQSQSTASNNASHNAALGGMWSQASNLVSLDLLGSSQSNQQQKPTSSRGPSMNSLKSSNVNTDWNNWASANTVTPQKKPTQPSANFDDLLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NQ89</accession>
    <name>A0A1C7NQ89_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Putative serine protease K12H4.7</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">K12H4.7_1</name>
        <name evidence="7" type="ORF">A0J61_02524</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S28 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000096">
        <property type="protein sequence ID" value="OBZ89434.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NQ89"/>
    <dbReference type="InParanoid" id="A0A1C7NQ89"/>
    <dbReference type="OrthoDB" id="1735038at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008239">
        <property type="term" value="F:dipeptidyl-peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070008">
        <property type="term" value="F:serine-type exopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.980">
        <property type="entry name" value="Serine carboxypeptidase S28, SKS domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008758">
        <property type="entry name" value="Peptidase_S28"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042269">
        <property type="entry name" value="Ser_carbopepase_S28_SKS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11010">
        <property type="entry name" value="PROTEASE S28 PRO-X CARBOXYPEPTIDASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11010:SF117">
        <property type="entry name" value="SERINE PROTEASE 16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05577">
        <property type="entry name" value="Peptidase_S28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 7" id="KW-0645">Protease</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="7"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011079"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OBZ89434.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="513" mass="58402" checksum="AAD515696CE8EC3E" modified="2016-11-30" version="1">MILTKSVIGLVLLSINCFVSGSFLLGNPKLGKISHSDAHARIFSASNRPANETAEKESLPARYGTFYMDMPLDHFAKDNVTFRNRYWVNTDYYQPNGPIIFANGGEAAVDSPAFTMVNTTMAQLAKKLNGAFIFMEHRFYGDSRPLANGFNYSTEVISKLNTDQALADMAYLLKNVKFADKEIPSVPETKVIVYGCSYSGNLAAWMKRKYPELVYAAVASSAPVQAQFDFYQYFDPIIRYGRPACIQAIEQMIAYVDKILSGSSTQAVNELKQLYGVPDLYDDDFASYLTTAIASYWQYGVSATNDQFEELICKKTFNSSSVEENAKSYANLLRPYVNQTYCEDYKDMTTCLDSHNATSIQEQKATNPDNAAWMYQTCTEYGYFQTASPKGYPTVVSRKLDIKWFERTCKLYFGNQVPKRPKISEFNKKYKGWNINLDRILWIDGEYDNWRELSVHSPSVKRSFDGNQTLSIIIPKATHCLNYNGITEKTPQYLRDIQELQYTTLKKWLDQAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NQU9</accession>
    <name>A0A1C7NQU9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Cellular nucleic acid-binding</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">byr3</name>
        <name evidence="4" type="ORF">A0J61_00463</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000010">
        <property type="protein sequence ID" value="OBZ91497.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NQU9"/>
    <dbReference type="STRING" id="101091.A0A1C7NQU9"/>
    <dbReference type="InParanoid" id="A0A1C7NQU9"/>
    <dbReference type="OrthoDB" id="3863715at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.60.10">
        <property type="entry name" value="Zinc finger, CCHC-type"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001878">
        <property type="entry name" value="Znf_CCHC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051714">
        <property type="entry name" value="Znf_CCHC_NABP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036875">
        <property type="entry name" value="Znf_CCHC_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23002">
        <property type="entry name" value="ZINC FINGER CCHC DOMAIN CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00098">
        <property type="entry name" value="zf-CCHC"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SMART" id="SM00343">
        <property type="entry name" value="ZnF_C2HC"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57756">
        <property type="entry name" value="Retrovirus zinc finger-like domains"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50158">
        <property type="entry name" value="ZF_CCHC"/>
        <property type="match status" value="7"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="CCHC-type" evidence="3">
        <location>
            <begin position="9"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="domain" description="CCHC-type" evidence="3">
        <location>
            <begin position="29"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="domain" description="CCHC-type" evidence="3">
        <location>
            <begin position="50"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="domain" description="CCHC-type" evidence="3">
        <location>
            <begin position="75"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="domain" description="CCHC-type" evidence="3">
        <location>
            <begin position="105"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="domain" description="CCHC-type" evidence="3">
        <location>
            <begin position="133"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="domain" description="CCHC-type" evidence="3">
        <location>
            <begin position="156"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="81"/>
            <end position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OBZ91497.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="173" mass="18563" checksum="F899F0049B7E9620" modified="2016-11-30" version="1">MSFRQGGACYKCGEPGHQARDCTKSDSVCYNCQQEGHVSRDCTEPRAEKRCYQCNQSGHLSRDCPDAFNSEGPACYTCGKSGHKSRDCYESGNSRGGYGGGSKSCYSCGDSGHLSRDCPSNSGGNSSWSSGPKCYNCGNTGHMSRDCDQPAQAKSCYKCSQVGHFARDCTSEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NQV5</accession>
    <name>A0A1C7NQV5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Mitochondrial dicarboxylate transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">DIC1_0</name>
        <name evidence="11" type="ORF">A0J61_00625</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000015">
        <property type="protein sequence ID" value="OBZ91299.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NQV5"/>
    <dbReference type="STRING" id="101091.A0A1C7NQV5"/>
    <dbReference type="InParanoid" id="A0A1C7NQV5"/>
    <dbReference type="OrthoDB" id="448427at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031966">
        <property type="term" value="C:mitochondrial membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.50.40.10:FF:000107">
        <property type="entry name" value="Mitochondrial dicarboxylate carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002067">
        <property type="entry name" value="MCP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050391">
        <property type="entry name" value="Mito_Metabolite_Transporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45618">
        <property type="entry name" value="MITOCHONDRIAL DICARBOXYLATE CARRIER-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00784">
        <property type="entry name" value="MTUNCOUPLING"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 9 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 10" id="KW-0813">Transport</keyword>
    <feature type="repeat" description="Solcar" evidence="9">
        <location>
            <begin position="4"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="9">
        <location>
            <begin position="100"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="9">
        <location>
            <begin position="196"/>
            <end position="282"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="OBZ91299.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="300" mass="32763" checksum="61F279BDBE84ACCB" modified="2016-11-30" version="1">MSTTKKTYPFYFGGAASCVAAVVVHPFDLTKVRLQNAKGSMKLSMFSTMVKIAQNEGFVNLYAGLSASILRQATYSTVRFGVYEKLRDKVQAQRKAGVMELLLCSSIAGALGGACGNPGDVINVRMQNDGQLPPQQRRNYKHALDGVLRISREEGTAALFRGLGPNVNRAILMTSAQCVSYDIFKYLILNHTTLQDGVPIHLTSSVLAGLVATTVCSPVDVIKTRIMSASASDQKMSASQIMKQMFKAEGVSSFFKGWTPAFIRLGPQTIITFVVLEQFKSWYDLLQSKSVSTKTIAHQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NRC6</accession>
    <name>A0A1C7NRC6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Signal transduction histidine-protein kinase BarA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">barA</name>
        <name evidence="5" type="ORF">A0J61_00249</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000005">
        <property type="protein sequence ID" value="OBZ91685.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NRC6"/>
    <dbReference type="STRING" id="101091.A0A1C7NRC6"/>
    <dbReference type="InParanoid" id="A0A1C7NRC6"/>
    <dbReference type="OrthoDB" id="21225at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd17546">
        <property type="entry name" value="REC_hyHK_CKI1_RcsC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050956">
        <property type="entry name" value="2C_system_His_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43719:SF28">
        <property type="entry name" value="PEROXIDE STRESS-ACTIVATED HISTIDINE KINASE MAK1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43719">
        <property type="entry name" value="TWO-COMPONENT HISTIDINE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="CheY-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="1 2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Response regulatory" evidence="4">
        <location>
            <begin position="136"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="26"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="26"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="2">
        <location>
            <position position="189"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OBZ91685.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="274" mass="30715" checksum="6CD59A7E7F81962F" modified="2016-11-30" version="1">MDYFAYTASKRRSISVEISLPNEVQTSTKDSQSVPTTPTVFIHDTGKSPSKPTCIRYSASFFMPEINQQESVEDATDRMINLSLLSTSLPSPPITPQQIVPHISLSLPSSASSDPIRNHKRRFSNPPHTVFSPRLHILLVDDNTINLQILSRLLNLHLNDVIEHLELVKNGVKALEVLKCRPFDLVLMDIDMPIMNGIETTKHIRSSTEFDILPHNRKAPIVAVTTNDSPKWRQLYTDIGMDGCISKPISPLDLKKTLTRVLGLHLPVPPYTPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NRG8</accession>
    <name>A0A1C7NRG8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_00344</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000007">
        <property type="protein sequence ID" value="OBZ91608.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NRG8"/>
    <dbReference type="InParanoid" id="A0A1C7NRG8"/>
    <dbReference type="OrthoDB" id="2259354at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ91608.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="275" mass="31816" checksum="0B9A9246E7FE1ACF" modified="2016-11-30" version="1">MTIIYTETHLTSDPEETSDSIVFQIALSTITFYCQTHREENISYIKAHKIRAGDVVRIYGILITVPEQYIKVSSIELVPFPSIGFKKRRIDEAFDNPHTQLHYKKYRSTDSCDTVSSMSLLPELIDNSPPKDEQLLDEKKEEDIYFDFGSNFGHYFYYLYGRAQFACSHVAQNAAKDNQKRTDKLKYEIEQCQQETGHDLNKLFTEIYQIATEATKRGFSRLSVVLFVSKVTEFLEKLKDLLNTCSSPIPFGLEQEDGIPLPSCIFEYYRTHIAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NRP2</accession>
    <name>A0A1C7NRP2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Heat shock protein, mitochondrial</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">hsp10_0</name>
        <name evidence="5" type="synonym">hsp10_1</name>
        <name evidence="6" type="ORF">A0J61_00323</name>
        <name evidence="5" type="ORF">A0J61_11131</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Eukaryotic CPN10 homolog which is essential for mitochondrial protein biogenesis, together with CPN60. Binds to CPN60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the GroES chaperonin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001703">
        <property type="protein sequence ID" value="OBZ80820.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="LUGH01000007">
        <property type="protein sequence ID" value="OBZ91630.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NRP2"/>
    <dbReference type="FunCoup" id="A0A1C7NRP2">
        <property type="interactions" value="433"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NRP2"/>
    <dbReference type="InParanoid" id="A0A1C7NRP2"/>
    <dbReference type="OrthoDB" id="184876at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044183">
        <property type="term" value="F:protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051087">
        <property type="term" value="F:protein-folding chaperone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00320">
        <property type="entry name" value="cpn10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.33.40:FF:000002">
        <property type="entry name" value="10 kDa chaperonin, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.33.40">
        <property type="entry name" value="GroES chaperonin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00580">
        <property type="entry name" value="CH10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020818">
        <property type="entry name" value="Chaperonin_GroES"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037124">
        <property type="entry name" value="Chaperonin_GroES_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018369">
        <property type="entry name" value="Chaprnonin_Cpn10_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10772">
        <property type="entry name" value="10 KDA HEAT SHOCK PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10772:SF0">
        <property type="entry name" value="10 KDA HEAT SHOCK PROTEIN, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00166">
        <property type="entry name" value="Cpn10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00297">
        <property type="entry name" value="CHAPERONIN10"/>
    </dbReference>
    <dbReference type="SMART" id="SM00883">
        <property type="entry name" value="Cpn10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00681">
        <property type="entry name" value="CHAPERONINS_CPN10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4" id="KW-0143">Chaperone</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0346">Stress response</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00056825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OBZ80820.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OBZ91630.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="100" mass="10833" checksum="D93C2A475747E8EA" modified="2016-11-30" version="1">MSALKNFVPLLDRVLVQRIKPQQKTASGIFIPEKAQEALNEGVVVAVGKGALNKEGQHIPLQVNTGDKVILPSFGGNPVKVAGEEYLLFRDSEILAKILQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NRR3</accession>
    <name>A0A1C7NRR3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">NADH-ubiquinone oxidoreductase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">B1O14.280</name>
        <name evidence="12" type="ORF">A0J61_00154</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 9">Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Mitochondrion inner membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the complex I NDUFA8 subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000003">
        <property type="protein sequence ID" value="OBZ91802.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NRR3"/>
    <dbReference type="SMR" id="A0A1C7NRR3"/>
    <dbReference type="STRING" id="101091.A0A1C7NRR3"/>
    <dbReference type="InParanoid" id="A0A1C7NRR3"/>
    <dbReference type="OrthoDB" id="276296at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006120">
        <property type="term" value="P:mitochondrial electron transport, NADH to ubiquinone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.2900">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010625">
        <property type="entry name" value="CHCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016680">
        <property type="entry name" value="NDUFA8"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13344:SF0">
        <property type="entry name" value="NADH DEHYDROGENASE [UBIQUINONE] 1 ALPHA SUBCOMPLEX SUBUNIT 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13344">
        <property type="entry name" value="NADH-UBIQUINONE OXIDOREDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06747">
        <property type="entry name" value="CHCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF017016">
        <property type="entry name" value="NDUA8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51808">
        <property type="entry name" value="CHCH"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="6 9" id="KW-0249">Electron transport</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 9" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="9" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 9" id="KW-0679">Respiratory chain</keyword>
    <keyword evidence="3 9" id="KW-0813">Transport</keyword>
    <keyword evidence="12" id="KW-0830">Ubiquinone</keyword>
    <feature type="domain" description="CHCH" evidence="11">
        <location>
            <begin position="90"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="132"/>
            <end position="155"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022660"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRNR" id="PIRNR017016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF06747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="OBZ91802.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="155" mass="17661" checksum="00809B77FEB509EA" modified="2016-11-30" version="1">MSSNQEATFTHTKFVDPTPLPDSIPKVDEVGATSAPLKSASFFIGEYCREYNDDFMLCKNENNDPKHCLAEGRKVTRCAIDLISKLRENCGKEFEAHWKCLENNNQDLFACRTPERAMNTCVFEKLGLKKRIPGSPEGQDQIHEKKNPVMKKHLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NRX5</accession>
    <name>A0A1C7NRX5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Rho guanine nucleotide exchange factor scd1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">scd1_2</name>
        <name evidence="5" type="ORF">A0J61_00214</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000004">
        <property type="protein sequence ID" value="OBZ91768.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NRX5"/>
    <dbReference type="FunCoup" id="A0A1C7NRX5">
        <property type="interactions" value="80"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NRX5"/>
    <dbReference type="InParanoid" id="A0A1C7NRX5"/>
    <dbReference type="OrthoDB" id="1594986at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000935">
        <property type="term" value="C:division septum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043332">
        <property type="term" value="C:mating projection tip"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005085">
        <property type="term" value="F:guanyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030010">
        <property type="term" value="P:establishment of cell polarity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035556">
        <property type="term" value="P:intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031106">
        <property type="term" value="P:septin ring organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05992">
        <property type="entry name" value="PB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd13246">
        <property type="entry name" value="PH_Scd1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00160">
        <property type="entry name" value="RhoGEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.418.10">
        <property type="entry name" value="Calponin-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.900.10">
        <property type="entry name" value="Dbl homology (DH) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010481">
        <property type="entry name" value="Cdc24/Scd1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033511">
        <property type="entry name" value="Cdc24/Scd1_PH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053026">
        <property type="entry name" value="CDC42_GEF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036872">
        <property type="entry name" value="CH_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035899">
        <property type="entry name" value="DBL_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000219">
        <property type="entry name" value="DH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001331">
        <property type="entry name" value="GDS_CDC24_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053793">
        <property type="entry name" value="PB1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000270">
        <property type="entry name" value="PB1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001849">
        <property type="entry name" value="PH_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47339">
        <property type="entry name" value="CELL DIVISION CONTROL PROTEIN 24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47339:SF1">
        <property type="entry name" value="CELL DIVISION CONTROL PROTEIN 24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06395">
        <property type="entry name" value="CDC24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00564">
        <property type="entry name" value="PB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15411">
        <property type="entry name" value="PH_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00621">
        <property type="entry name" value="RhoGEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00666">
        <property type="entry name" value="PB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00233">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00325">
        <property type="entry name" value="RhoGEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54277">
        <property type="entry name" value="CAD &amp; PB1 domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48065">
        <property type="entry name" value="DBL homology domain (DH-domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00741">
        <property type="entry name" value="DH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50010">
        <property type="entry name" value="DH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51745">
        <property type="entry name" value="PB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50003">
        <property type="entry name" value="PH_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DH" evidence="3">
        <location>
            <begin position="206"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="domain" description="PH" evidence="2">
        <location>
            <begin position="404"/>
            <end position="528"/>
        </location>
    </feature>
    <feature type="domain" description="PB1" evidence="4">
        <location>
            <begin position="787"/>
            <end position="871"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="534"/>
            <end position="658"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="723"/>
            <end position="742"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="534"/>
            <end position="550"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="556"/>
            <end position="575"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="577"/>
            <end position="597"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="615"/>
            <end position="637"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="646"/>
            <end position="658"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51745"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OBZ91768.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="871" mass="99141" checksum="ACED11176E37127D" modified="2016-11-30" version="1">MATLTLKNRSPSIGAINTVATNMIDVPLPSVSITNKPSSGTSLYHKCRSVLDRLALVEGMTYYLDYDSFGPVLSSNSSVVSSESTSSHNSNDPLSKLWDLCRRGAPLATLFNALHPAEPLKLDFTQTQQVNECKKTVYHFIVACRNQLEFKEGDLFTLSDLYKDNTNGFVKVVNTIDLVLQLLEEKGIISSHSSENRNSTNAPKDTRDKVVHELLETERKYVQDLEVLQNYMRELQMNDILNPDTIHYLFGNLNTLVDFQRRFLFQLEEIAEKSPEEQNFGLLFTQMEEQFTVYEPYCSNYFSAQDLVVQEAPKLQKLANILNPQYELPSMLIKPVQRICKYPLLLQQLIKSTQPDWPHFDDMETGLESVKRVTERVNETQRKHENIQVLDDLKRRMDDFRVKHIDNFGCLLLHDKLVIQQSDETEKEMFVFFFEKTLLICKETKDANKNKGVKANTISIKKKRRGSLQPKGLIDIRRILSVRNLSVGEGSWYLRVDWKDNDVDHVLFRFRNEEQVKLWESTLKRKISPMKSNVSNTQLASMKNAAQSVPASFRTDDEDEEEESLDTDTEDEEGEFQPQQSRSRSNSISAHLFNTISGRPKAPRHNTDIKNQRYTTTPFPRTSTSTGTHHSSDYSYPASPPPSTPSSPTSSSRTRTGLRDSSALVDIAHKFMSSDNDTVDEIKMYPPYINRSQSHSAATPAYPPTSTIPSVYHLQQLPRLRSQSSPNIHNQTSRQPQWEDTMQLPPFSSRTLYHMPPSPLDPPSSVRMVSSATTSPILSPNLAMPGALKVKLNYNAGIYVVMCPPDISFEVLMEKVDRKIRLIGNLQPQDTLRLRYQDEDGDLITINSNEDVQMAFESRGNANAVNLFVSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NS25</accession>
    <name>A0A1C7NS25_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Poly(A)-specific ribonuclease PARN</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">parn_0</name>
        <name evidence="3" type="ORF">A0J61_00212</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CAF1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000004">
        <property type="protein sequence ID" value="OBZ91770.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NS25"/>
    <dbReference type="FunCoup" id="A0A1C7NS25">
        <property type="interactions" value="663"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NS25"/>
    <dbReference type="InParanoid" id="A0A1C7NS25"/>
    <dbReference type="OrthoDB" id="1432093at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000175">
        <property type="term" value="F:3'-5'-RNA exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1370.50">
        <property type="entry name" value="R3H-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051181">
        <property type="entry name" value="CAF1_poly(A)_ribonucleases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036867">
        <property type="entry name" value="R3H_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006941">
        <property type="entry name" value="RNase_CAF1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15092">
        <property type="entry name" value="POLY A -SPECIFIC RIBONUCLEASE/TARGET OF EGR1, MEMBER 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15092:SF22">
        <property type="entry name" value="POLY(A)-SPECIFIC RIBONUCLEASE PNLDC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04857">
        <property type="entry name" value="CAF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="393"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="393"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="413"/>
            <end position="431"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008372"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ91770.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="559" mass="65198" checksum="F0547D967812F412" modified="2016-11-30" version="1">MEITRQQFSQKLSAVQKAIKECDFMAIDTELSGLHRPPTSIRLYNMKDRYQEYKEATERFIIIQFGLCTFQWDEPSGRYIAKPFNFYIFPTSITGHIQTNRIFMTQAQAFDFLTKQSFDFNKWVYQGIPYMTRAEEEAYVSAATKKLKDDMPDIPIDAKELDFVNNARNLIQDFLTKTKEESEGVNIVTKNAYQRRLIYQEARKFEGITAIGMQGFIRVVKLSKEQHDSRNREKQEKFEKDCEVAVGFRKVIDMISESGKLVIGHNMLLDICHVIAQFVEPLPETLSEFKQLAHRVFPKMIDTKHMSMSEPELITIFGSGTSLEVLRFETKKETFKNPHIDMHAEFPRYLTEMAHEAGYDAFMTGAVFLKMVGYLDEKRNPDKYTAIRSEREALEREKEKERERRSEKKVDADGWEISEDEEEQADSAWNNDEEEIYNYGSIRLDIEDKQGKMSNVYSNIMNKAALVRTAFEYFDFTDQSPALGQVQALHVSHKPDFTFTKELADSLFLEHGKYIVEPKDDQSLYIVFENLRKDIESLNISHEELTIKPVINKSLDEML</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NS60</accession>
    <name>A0A1C7NS60_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_00161</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000003">
        <property type="protein sequence ID" value="OBZ91789.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NS60"/>
    <dbReference type="InParanoid" id="A0A1C7NS60"/>
    <dbReference type="OrthoDB" id="2269470at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ91789.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="58" mass="6439" checksum="DD57EC29D50408D8" modified="2016-11-30" version="1">MAKIGKALAVSFGALAGGAGGFYLLEMYKIRSKEQRLAMLLEKKKEYENLQKNNESSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MU39</accession>
    <name>A0A1C7MU39_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_11580</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01002219">
        <property type="protein sequence ID" value="OBZ80371.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MU39"/>
    <dbReference type="InParanoid" id="A0A1C7MU39"/>
    <dbReference type="OrthoDB" id="5599418at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00303">
        <property type="entry name" value="retropepsin_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.70.10">
        <property type="entry name" value="Acid Proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021109">
        <property type="entry name" value="Peptidase_aspartic_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08284">
        <property type="entry name" value="RVP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50630">
        <property type="entry name" value="Acid proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="17"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="290"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ80371.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="290" mass="32505" checksum="391A92B94BE725C0" modified="2016-11-30" version="1" fragment="single">MPDHNEKKDKRPKNLGTHRSNLQQVTSVQSGSISSDSNEKIDENDLLDFTDNIFYNLCNQNSQGYIEEEEQFVPNAMGRLRGRTNFSLPCVIKPTSNTNAANTTVLIDTGAMISSISEEEATRLGLQVEDAPPIRITYGNSSSDVSGEAVRMPCEIQRVDYGLVYLRTVKKQNVPILLGMDWLLKTRVLVDPYEKTLIPRDKLLDLVSLNNQQVKEITASIQKVAETPTEIQAILLLLPKLYNEEEVQTITNAPISHRIDTGDTNPIVKKGRRLSPKESQVVETEVEKLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MUM6</accession>
    <name>A0A1C7MUM6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Transposable element Tc1 transposase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">tc1a_4</name>
        <name evidence="1" type="ORF">A0J61_11815</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01002529">
        <property type="protein sequence ID" value="OBZ80136.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MUM6"/>
    <dbReference type="STRING" id="101091.A0A1C7MUM6"/>
    <dbReference type="InParanoid" id="A0A1C7MUM6"/>
    <dbReference type="OrthoDB" id="5410741at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ80136.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="113" mass="12906" checksum="8C5F2EBFE8089F0D" modified="2016-11-30" version="1">MDSNLHIEILDDKLIKTLDYYGYSEDTHLEDCGIEVVDLPAYSLDLNPIENLRGVLKRRLAGYSTPPDSIYELFARVTEVWNNIEPTICEKLTESMPDRVQQVIDANGGQIDY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MUN8</accession>
    <name>A0A1C7MUN8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Reverse transcriptase/retrotransposon-derived protein RNase H-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_11370</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001959">
        <property type="protein sequence ID" value="OBZ80581.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MUN8"/>
    <dbReference type="STRING" id="101091.A0A1C7MUN8"/>
    <dbReference type="InParanoid" id="A0A1C7MUN8"/>
    <dbReference type="OrthoDB" id="2282011at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043502">
        <property type="entry name" value="DNA/RNA_pol_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050951">
        <property type="entry name" value="Retrovirus_Pol_polyprotein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041577">
        <property type="entry name" value="RT_RNaseH_2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37984">
        <property type="entry name" value="PROTEIN CBG26694"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37984:SF5">
        <property type="entry name" value="PROTEIN NYNRIN-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17919">
        <property type="entry name" value="RT_RNaseH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56672">
        <property type="entry name" value="DNA/RNA polymerases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Reverse transcriptase/retrotransposon-derived protein RNase H-like" evidence="2">
        <location>
            <begin position="213"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="305"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF17919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ80581.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="305" mass="34090" checksum="D9609E7678FAB332" modified="2016-11-30" version="1" fragment="single">TASKTSSTYGYTSRLKLKYNGKIYEFKFQVVDLTFNVTMSIGTDLMRVLGIGYHGLDPPVKGVTENPLEDIIASNEALPPGSFCTHPDAVVYLDTPGAAEGYKSQYPIAHNLKPKVQETVKDTQGKCTDKRPCLDPRHINKYLKEDRFLLPKINDIFRKLQDANTHARLQTLCNGQHRALRFLKVVNCFRHDVPKIAALTAPIDGLRKHPGAAHDVAFHKLKQALIHASILQPLNLGLPFQVARDASDVGIGAVLYQEAVSSKKLHYIGLMARALTKSERNYGTTKRELLAIVFALQRFHTYLWG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-06-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MUQ0</accession>
    <name>A0A1C7MUQ0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_11421</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01002015">
        <property type="protein sequence ID" value="OBZ80530.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MUQ0"/>
    <dbReference type="InParanoid" id="A0A1C7MUQ0"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ80530.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="147" mass="16966" checksum="EC182875B1756BF8" modified="2016-11-30" version="1">MQVLPSMTRDRHFDEVKYKITSAAISLLKTQIMLYHDEKASDKQKECSRRFRSVYKLPCRHEFDAESSNMPISLQLVDRRWFVSCDVDKKVEEMCPAVTESQATDSVGINTQDVNSLVTSALYKLEHTLNTCDDKNCKITIVKQIEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MUZ4</accession>
    <name>A0A1C7MUZ4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Integrase catalytic domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_11298</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001879">
        <property type="protein sequence ID" value="OBZ80653.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MUZ4"/>
    <dbReference type="STRING" id="101091.A0A1C7MUZ4"/>
    <dbReference type="InParanoid" id="A0A1C7MUZ4"/>
    <dbReference type="OrthoDB" id="2288803at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015074">
        <property type="term" value="P:DNA integration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.340.70:FF:000001">
        <property type="entry name" value="Retrovirus-related Pol polyprotein from transposon gypsy-like Protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.340.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001584">
        <property type="entry name" value="Integrase_cat-core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041588">
        <property type="entry name" value="Integrase_H2C2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050951">
        <property type="entry name" value="Retrovirus_Pol_polyprotein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37984:SF15">
        <property type="entry name" value="INTEGRASE CATALYTIC DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37984">
        <property type="entry name" value="PROTEIN CBG26694"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17921">
        <property type="entry name" value="Integrase_H2C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00665">
        <property type="entry name" value="rve"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50994">
        <property type="entry name" value="INTEGRASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Integrase catalytic" evidence="1">
        <location>
            <begin position="105"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="410"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50994"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ80653.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="410" mass="46255" checksum="D219F34CF6996DA3" modified="2016-11-30" version="1" fragment="single">GDSYCKQLRQASLPLGFSDESGILLFGSRPVLPECLQNEVFNLLHDHPTSGHLGIGRTLQRFSRLYYLPNMKEWITDKVNQCETCQRIKRTNYSFGHTKLVHAGAASHPFDVLAIDTFGPLPPSRSGNRYVIVVQCAFSRYVSLFAVPENNDQHLVRCLSHIIGEHGLFRVLLSDNGAPYSGTLIRSLAKYLGIEQRFAPAYHASSNGLVERFMETLKNMMSSYLQVNQKQDTWDVHLPEFQLAYNSSPHQTTKYTPFSLVHGHEARLLASHNIDTVQLPLGEYVFQQREFLTQAHKVILAENRRSQAHNAVQFNKHRKPPTFVANDLVLVDCPVLSNAARGRSQKLIPRFRGPFRITDVLSTDRYNVVHISSHKPMNNVHASRLKRYLCNGDIASANPPDVTSDPSIGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MV52</accession>
    <name>A0A1C7MV52_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_11315</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001900">
        <property type="protein sequence ID" value="OBZ80637.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MV52"/>
    <dbReference type="InParanoid" id="A0A1C7MV52"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="29"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="33"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="48"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ80637.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="61" mass="6562" checksum="9E391BCB92680C6B" modified="2016-11-30" version="1">MLQSLAYAEFCMPLSFSSFLPVDEASASTGVVDGDRSDYGSDHESEASNDNDSISFESESE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MVP7</accession>
    <name>A0A1C7MVP7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_11057</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001633">
        <property type="protein sequence ID" value="OBZ80893.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MVP7"/>
    <dbReference type="InParanoid" id="A0A1C7MVP7"/>
    <dbReference type="OrthoDB" id="2283743at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ80893.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="105" mass="11635" checksum="07C96DEAF7C92B54" modified="2016-11-30" version="1">MISVPKKAESITLRYCEVKAQDVEANAELAFADLARLSTFSRNLMLRKENKKAIPIQAIGYRVIIYFIGKAFPGVTIMSEILSFDVPTVTPRNNEFGIAGFPALP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MVQ9</accession>
    <name>A0A1C7MVQ9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Ndc10 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_11104</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001676">
        <property type="protein sequence ID" value="OBZ80847.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MVQ9"/>
    <dbReference type="STRING" id="101091.A0A1C7MVQ9"/>
    <dbReference type="InParanoid" id="A0A1C7MVQ9"/>
    <dbReference type="OrthoDB" id="2204095at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.443.20">
        <property type="entry name" value="Centromere DNA-binding protein complex CBF3 subunit, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011010">
        <property type="entry name" value="DNA_brk_join_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038279">
        <property type="entry name" value="Ndc10_dom2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031872">
        <property type="entry name" value="NDC10_II"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16787">
        <property type="entry name" value="NDC10_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56349">
        <property type="entry name" value="DNA breaking-rejoining enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ndc10" evidence="1">
        <location>
            <begin position="46"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="325"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF16787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ80847.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="325" mass="36768" checksum="CEB162117F74B57F" modified="2016-11-30" version="1" fragment="single">MQIRVVVGAPNRRVGLATVKMYIAAVVDLYNEQALADPHSHRPHPREDLCDGVTFLLQHYGLLRDESLRVMEFPGLQSILLEIEGIITPCYALVMVLKQGKTNQEGRLEFAACLRNKNVRICAQMMLAFYLFSRWHVHAEPFPEFNENRDWFDIKLTRSRQSSKKVISYDHHLRSIKDAVKAVGLHSKAKTHATRGSGSRMVEMLGANGAAIRRLGCWNNSVLTNNYLTHLPREALRTLAGFTSDAGQFYLVRATIVPSEDLCKKAYPYVDGWLEKLAKGEVTESSTAADGFLQLLAQLRIVFLQGSVVIKKVFPDHFLWNDPLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-06-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MWL2</accession>
    <name>A0A1C7MWL2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_11122</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001694">
        <property type="protein sequence ID" value="OBZ80829.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MWL2"/>
    <dbReference type="InParanoid" id="A0A1C7MWL2"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ80829.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="77" mass="8876" checksum="425C1BF604D3BD43" modified="2016-11-30" version="1">MQSSDTEASILNYGVLRLSISFSLGKMIEYSEKAGNPCGFEPMTKDRKIELSWAKTATNYLTEEDFKCMVDYYWKTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MWN0</accession>
    <name>A0A1C7MWN0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Glutamate decarboxylase 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">GAD2</name>
        <name evidence="7" type="ORF">A0J61_11102</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 6">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the group II decarboxylase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001675">
        <property type="protein sequence ID" value="OBZ80849.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MWN0"/>
    <dbReference type="STRING" id="101091.A0A1C7MWN0"/>
    <dbReference type="InParanoid" id="A0A1C7MWN0"/>
    <dbReference type="OrthoDB" id="392571at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016831">
        <property type="term" value="F:carboxy-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019752">
        <property type="term" value="P:carboxylic acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002129">
        <property type="entry name" value="PyrdxlP-dep_de-COase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45677:SF8">
        <property type="entry name" value="CYSTEINE SULFINIC ACID DECARBOXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45677">
        <property type="entry name" value="GLUTAMATE DECARBOXYLASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00282">
        <property type="entry name" value="Pyridoxal_deC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="5 6" id="KW-0456">Lyase</keyword>
    <keyword evidence="4 6" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OBZ80849.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="193" mass="21799" checksum="2CAE6D54B356F43B" modified="2016-11-30" version="1" fragment="single">ADSFTLNPHKLLGVPLQCSMLITPHRGHLLFAQANALKADYLFHGNPYDLGAGTIGCGRRADAVKVFLAWKFYGQAGLGERVDRALDCASQFAEMVKRREGFVLVKDPIPFLQICFWFVPPQLRGRDDLDLSTLTRELHRRINQSGEFLVDHAPLAGQPDFFRVVVNAPTVHLYRDLERLLDAIEEASELIEW</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MXQ0</accession>
    <name>A0A1C7MXQ0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_10411</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001159">
        <property type="protein sequence ID" value="OBZ81541.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7MXQ0"/>
    <dbReference type="InParanoid" id="A0A1C7MXQ0"/>
    <dbReference type="OrthoDB" id="2288803at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ81541.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="121" mass="14637" checksum="A63F0AA2C67C0F61" modified="2016-11-30" version="1">MHHSQIKTSPFELVHGRKARTPIYLTEEDQELHYXKQYRNTDTPXLHFAKELXKNLNTTFAFXHKHIKQYDEVSDSYGYKKXDKVLIFNMQXSTARKPRKLAYDWHGPFMKYTYFFDETFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MXS5</accession>
    <name>A0A1C7MXS5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">40S ribosomal protein S1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">rps1</name>
        <name evidence="4" type="ORF">A0J61_10381</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001145">
        <property type="protein sequence ID" value="OBZ81571.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MXS5"/>
    <dbReference type="STRING" id="101091.A0A1C7MXS5"/>
    <dbReference type="InParanoid" id="A0A1C7MXS5"/>
    <dbReference type="OrthoDB" id="9834376at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001593">
        <property type="entry name" value="Ribosomal_eS1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11830">
        <property type="entry name" value="40S RIBOSOMAL PROTEIN S3A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01015">
        <property type="entry name" value="Ribosomal_S3Ae"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4" id="KW-0689">Ribosomal protein</keyword>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OBZ81571.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="71" mass="8000" checksum="F780BF957E25911B" modified="2016-11-30" version="1" fragment="single">MAVGKNKRLSKGKKGLKKKVVDPFTRKDWYDIKAPSMFDVRQVGKTLVNRTQGLRNANDSLHGRVVEMSLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MYE3</accession>
    <name>A0A1C7MYE3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_10526</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001216">
        <property type="protein sequence ID" value="OBZ81426.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MYE3"/>
    <dbReference type="STRING" id="101091.A0A1C7MYE3"/>
    <dbReference type="InParanoid" id="A0A1C7MYE3"/>
    <dbReference type="OrthoDB" id="2271399at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ81426.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="363" mass="41543" checksum="A8734E1F2930992C" modified="2016-11-30" version="1">MFTPKRCEFDHLLEVHFRVVASLCKKDNSSVRARTYIHKTIGHKREFKVIDQILDILDEEKFLLQNIADTSLITESDIMGKIWIPLIKKVLFVRGNLVRTKVGETIPPHSQEEKMLQYDDAKNIKAFKVDIRFIFDLEGKEYDVGAGEVARETADKAKILHDKSKLLREGKDVLDGILKAVIVEGNAQKAVGHAIQIKGLCAQVISVYLTNTGLYVAIPVFKIYFPISLLHLNDFADGLKNMFRFVDFLCDNAKLYESAIMSRKRRISSIDFDYNMQQRKLPAHSLLGLIKPTYYSPVNNDRFCSVFDLPDTKESRDTPSPEPNVEEGFAFTSNTDENGWIMLDSGNWFHRETNITLNNSPYE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MYY9</accession>
    <name>A0A1C7MYY9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Ndc10 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_09921</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000972">
        <property type="protein sequence ID" value="OBZ82033.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MYY9"/>
    <dbReference type="STRING" id="101091.A0A1C7MYY9"/>
    <dbReference type="InParanoid" id="A0A1C7MYY9"/>
    <dbReference type="OrthoDB" id="2277573at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.443.20">
        <property type="entry name" value="Centromere DNA-binding protein complex CBF3 subunit, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038279">
        <property type="entry name" value="Ndc10_dom2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031872">
        <property type="entry name" value="NDC10_II"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16787">
        <property type="entry name" value="NDC10_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ndc10" evidence="1">
        <location>
            <begin position="150"/>
            <end position="426"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF16787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ82033.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="428" mass="48427" checksum="4810BC5028F305E3" modified="2016-11-30" version="1">MIDVNTAMYRSNQMVLAEGKASRPVNTIKAYASKQRDCKQWCQEKKFADGEIVSDSKLSFFLDDHVMARGRKKQRAEDGSPVPLGKESILAYVKAVSDLYNTQKALKINSNEAARGPLVRTFLDNLEKTKTKQKRANFEDRGKNTLNDGYTKEELMKISQYFINQKNDINGSRDRLCFLISHAMLCRSQTALGLQFPDLFAITLENQGITKCISLVAAISFGKTNQHGKIEYGSSIHHKQVELCSVGALALYLFSRFYFENEEFPDFSERKNWYETVVFKGKDQKTAIIYQAQHKIYFGAFKNVGIHTSKVTHANRKSALNMIAQKNVPGDQQRMVGRWGTDRMVGCCVSSLPVDATKSLAGFPVASNNYFLPRAVVIPPMDLQVQVFPQVDIWKQRFELQDGVQEDIAGPNFLNLLSNLRTVFLQVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MZ29</accession>
    <name>A0A1C7MZ29_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_09932</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000974">
        <property type="protein sequence ID" value="OBZ82021.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MZ29"/>
    <dbReference type="InParanoid" id="A0A1C7MZ29"/>
    <dbReference type="OrthoDB" id="2277186at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ82021.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="203" mass="22962" checksum="E923A28116443112" modified="2016-11-30" version="1">MTTHQKPKFKKLESTDSLPAIPKEAREIDKNAWSFVERQPPVLPVFEEEEEREEDTITPSTPPLLAFIKGHAQHFISSTLQFVFKDNNLPLIINIAHHLLVARMLIARSSKSVSRYLNIPSTVALATHSPLRHQIEQTHLVATDSFRAQGVLHLALGLLSILALKERRISSERSALLVLTLASAGQAWSHCYKRCVYPNYVWP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MZR9</accession>
    <name>A0A1C7MZR9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">A0J61_09587</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the UPF0014 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000885">
        <property type="protein sequence ID" value="OBZ82360.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MZR9"/>
    <dbReference type="InParanoid" id="A0A1C7MZR9"/>
    <dbReference type="OrthoDB" id="432685at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005226">
        <property type="entry name" value="UPF0014_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30028:SF0">
        <property type="entry name" value="PROTEIN ALUMINUM SENSITIVE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30028">
        <property type="entry name" value="UPF0014 INNER MEMBRANE PROTEIN YBBM-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03649">
        <property type="entry name" value="UPF0014"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="39"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="63"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="97"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="131"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="189"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="229"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="291"/>
            <end position="320"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OBZ82360.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="320" mass="35382" checksum="9BFAD69F8757251B" modified="2016-11-30" version="1">MGAIDQPELTWWNVGEASTALMVAAIVSMILGVKLELSLLISGIRCVLQLSLMGLVLDDVLKTKHMSIVIAMSIVLVILGTYETVFNRTRKTFQGMFPIMFGILLVSNLVITYIGAAFVLDTKPFWDPPTFIPIIGMLLGNSMSSVAMGIERCLDQFSTHAPMLETRLSFGASRYEAGLPLAVDAIRMALLPVITQLSVMGMINIPGMMTGQIMAGTPMMEAVIYQQCIMFMVAASSTLGVVMSVAACLSVLIDKDQTMRQDRIKDNRSFHHYFTRSLDHLPNQQNDLLSKRHSQASPQHPSKPGSHEAMRIQQSYRQRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N079</accession>
    <name>A0A1C7N079_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_09396</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000841">
        <property type="protein sequence ID" value="OBZ82555.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N079"/>
    <dbReference type="STRING" id="101091.A0A1C7N079"/>
    <dbReference type="InParanoid" id="A0A1C7N079"/>
    <dbReference type="OrthoDB" id="2153288at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101898">
        <property type="entry name" value="NHL repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="5"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="90"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="597"/>
            <end position="616"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ82555.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="623" mass="72050" checksum="4FBAAE27D33EE2EA" modified="2016-11-30" version="1">MKWRVLVLSIAGVAMIYFVSLLRDTPYPHPVLVQTFTPKRSRLNEPSEVLLKHHGDYIYRTHIHFEAVLEANKGYVRGVDSVKLGVNGNFLYSPLCSFVLISFLFFIGVVIQARKRKQDFLKSSTEEEWETCFKHLLRGPISRVGRMPEGNEGAQFAVLHHLIEDDEVQHLVRVYYHVENQYHYKDLILPGNTMVDAISLENDSILFSRDPDNYRFRIMQLPKELLLPPHSEQSQPIFLTAGQTGEPVRRKEPRDDFTMKARNANHAFYKKKIAYHQPKGTDAHASALAKLYSSKYVEFASRKKKRVLLSDLFLDVHSHHTYRVFSLDIHKTKSYFHTNVSVSDGVVVLSKQSNLQLGHWIRQDHLYSNDSIIVDENLEYMAFVDGAHFHHERTVISMPIPTVSRSRDAKTMVVSLIHNDFQTLDFTDNIQSLMENPYDRRHLYKDEEGHVIHEFYHTMQIPDSIEPYSTETGSAYDATDIRGVQLNEEGTLLAVWTESNSVYIYKRGSGDRLAYERKQSISESPHHLEKPLEWILRMVVTPKEGHLGFVTPIGSVMFWQKEGANYLSVGMKNNIVNTYLIDEMEEEQQAVKLTTNIVFLFSIAQVMTTVTMLFVVNEYKMYP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N0G9</accession>
    <name>A0A1C7N0G9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Septin spn4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">spn4_3</name>
        <name evidence="10" type="ORF">A0J61_09448</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="6">Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000853">
        <property type="protein sequence ID" value="OBZ82498.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N0G9"/>
    <dbReference type="FunCoup" id="A0A1C7N0G9">
        <property type="interactions" value="27"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N0G9"/>
    <dbReference type="InParanoid" id="A0A1C7N0G9"/>
    <dbReference type="OrthoDB" id="416553at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032161">
        <property type="term" value="C:cleavage apparatus septin structure"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031105">
        <property type="term" value="C:septin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000281">
        <property type="term" value="P:mitotic cytokinesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd01850">
        <property type="entry name" value="CDC_Septin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000162">
        <property type="entry name" value="septin-7 isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030379">
        <property type="entry name" value="G_SEPTIN_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016491">
        <property type="entry name" value="Septin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18884">
        <property type="entry name" value="SEPTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00735">
        <property type="entry name" value="Septin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006698">
        <property type="entry name" value="Septin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51719">
        <property type="entry name" value="G_SEPTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="1" id="KW-0132">Cell division</keyword>
    <keyword evidence="3 7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4 6" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="2 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008889396" evidence="8">
        <location>
            <begin position="20"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="domain" description="Septin-type G" evidence="9">
        <location>
            <begin position="42"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="357"/>
            <end position="391"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU004560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51719"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OBZ82498.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="401" mass="47256" checksum="9DE9C4FDB308A2FF" modified="2016-11-30" version="1">MPFIHFFLFFFVSFIIIQTMPSPFVAGIAHLPNQAHRLKAKTGASFNLMVCGESGLGKTTFINTLFATTIKEYKSPEKRHSRQFDRTVNIEVTKAELEEKKFRLKLSVIDTPGFGDYVNNRDSWVSIVEYIDEQLESYMQQEQQPFRQGKFDMRVHACLYFIRPTGHSLKSLDIEIMKHLCSRVNLIPVIAKADTLAPNDLLRFKQNLRESIEANNIKIYRCTIESEDEETTERNQRTADASPYAIIGSTEWVTTPDGRQVRGREYMWGTAEVENRDHCDFVQLRNLLIRTHMMDLITLTEQIYYETYRQEQMTSRTFGEQKKKKEEHPKFREKEEALRKMFTDKVKNEEIRFRQWEQQLIAERDRLNKDLEAQHARIKLLETELEQAYQLNGRSSSLNKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N123</accession>
    <name>A0A1C7N123_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Centrosomal protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">CEP104</name>
        <name evidence="3" type="ORF">A0J61_09261</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000810">
        <property type="protein sequence ID" value="OBZ82688.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N123"/>
    <dbReference type="InParanoid" id="A0A1C7N123"/>
    <dbReference type="OrthoDB" id="66599at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005929">
        <property type="term" value="C:cilium"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052607">
        <property type="entry name" value="CEP104-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048739">
        <property type="entry name" value="CEP104_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048738">
        <property type="entry name" value="CEP104_Znf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001943">
        <property type="entry name" value="UVR_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13371:SF0">
        <property type="entry name" value="CENTROSOMAL PROTEIN OF 104 KDA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13371">
        <property type="entry name" value="GLYCINE-, GLUTAMATE-, THIENYLCYCLOHEXYLPIPERIDINE-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21040">
        <property type="entry name" value="CEP104-like_TOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21038">
        <property type="entry name" value="CEP104_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21039">
        <property type="entry name" value="CEP104_ZnF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50151">
        <property type="entry name" value="UVR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UVR" evidence="2">
        <location>
            <begin position="274"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="757"/>
            <end position="879"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1004"/>
            <end position="1037"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="757"/>
            <end position="768"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="788"/>
            <end position="812"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="813"/>
            <end position="822"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="824"/>
            <end position="852"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1013"/>
            <end position="1026"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1027"/>
            <end position="1037"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ82688.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="1037" mass="116633" checksum="E0FA8BECCA12E909" modified="2016-11-30" version="1">MSSLPYEVVHCSSWDEGFSPEQLVMSSPGNQAEPKSGKCKGWQTTKCPDYPQDLIIHLLSGASRISKVQILSHHFMIATKIDVYIGVLKDPQDLLDDIAPDTPPVDDEDNMLIEFTRLGYVSFENNARAQFRARELKSIKINGDGEYVRLVIRNCHHNRLNTYNQVSILALNVMGQPLHLLDKHEIACSSSSNYTPQARHLFDDSSVLSSSTRRTSVSSNQSQLMRMPTGSVAEMELQRWSTALLQAEEEAVQGESYQIAKTYKYLGDKLSRFTKILSDLEMGKRHAVETKDYDEAEKIKDDIQEIRQAAEAMLKHANVHITDDDQVILLESSEALAAIQEVNDFISEQEQYRQSSPYMEYHRHDSPSQQDFLDDTVVCSEPMMPPLAKELEPDHWDLHMPSHRHHHYLDEHEEIHIPASYSSKVVPTQPTIIPLSPPSKPLKEDVDPDTIPEPIMDEERIPYTLPIHIFGEEVVACVLSVKAKCRGRGLGQIEEKIQAVGQLVETDQLEEVTFMIYFDEPYEDEEYADVDKLTSSLSHFINASLMMIQEAIMDSREPIVSLAITVWHQLNDVYKSCDLETKYIIEWTERAFSGLLKRTGDTNTKIKTAATKLVLSLVKDYSQPPYALMPLYVCKPERMIHNYKEAKCRVELVEATVKKFGVSSPSSTDTKTKKKAADQVCLQDLMDFVVAYLNHSHEDVKEAAIKLVITISDQVGFQLVSTYIDESLRLSLTETVKKLVDKDDMFNKTSANVTETQKKSRLSKESKNKSALSELRALTVVKSEKKSSATTRPSTAKKTTTTTTKAASAAATADKKSADKKTARSTTATPTARKTKTPTAKSNTSTKKAATTEPSKSTKPVNKDKVQQDAGEDNSTLKGDAELDENSVCIFCDEVNPAFNEDTLIKHYYNTCPVLTNCPMCQIITEVSTLNEHMLLDCDRKHLIKECSRCHQAIPVEQWLQHTLKKTCNNDPNKVQCPLCLIEIDPPNEIGWKSHLMTGDGCPKLKKSRSPVKKTSTVPVVSQTQQVKKKTTVTRKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N183</accession>
    <name>A0A1C7N183_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_10826</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001424">
        <property type="protein sequence ID" value="OBZ81124.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N183"/>
    <dbReference type="STRING" id="101091.A0A1C7N183"/>
    <dbReference type="InParanoid" id="A0A1C7N183"/>
    <dbReference type="OrthoDB" id="2276331at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10492">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10492:SF57">
        <property type="entry name" value="ATP-DEPENDENT DNA HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ81124.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="131" mass="15188" checksum="351FDB663F56D10D" modified="2016-11-30" version="1">MDGRSHRVQIKEKQTNEMKSVYLTNQNVVPYNPFLTKKYKAHINVELCGTVGAIKCINKYVYKGPDRTTVHLKNENDEIERYLTSRYIGPTEAVWCLFEYAMHEEDPSVTSLANHLENEQSVYFDPEAIAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N1C8</accession>
    <name>A0A1C7N1C8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Bromo domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_09139</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000782">
        <property type="protein sequence ID" value="OBZ82811.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N1C8"/>
    <dbReference type="InParanoid" id="A0A1C7N1C8"/>
    <dbReference type="OrthoDB" id="21648at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="460"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="299"/>
            <end position="326"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ82811.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="486" mass="55532" checksum="6298B7FBB77925D5" modified="2016-11-30" version="1">MPTTRHLSASTKSTSTDTQKINSTLEMRQKNFESRKKRVLPSDMLPVQKTMIQLIEHAINIDQSHLLWSHPLETDALSFEKVIHRTYEGTYKDFASLKADLETVFASTAYIIGRTRLDLDALRSLYVEVESSLILEASRHDEALKPSQDLFKLVALFRPTSDGYVFTDTMPKDPSAGPKHHYPNGIQEVIVHTTQPIETAPTLKETVAPPPKFHSKLPKHEHKPSLPVQWLDFGAFSSFAPASDSNNATMTYQDTVIGRSTKRLKKEEPEEMENDDHELNAAWLAKEGLDIHLLEEAIHAQSDIAAEELEQNRQLLEQLIDFQRKRFNQEDQSKWDQIDEKELEAANALENNMKEILSRLPPNSITAPSHLIEDAMERLPLFEPAYRGTLPPHKIFSFPTTEKAENLPPYANITPTYQKDNWRLVKVAPVPPKEMTSNTPSFPIVSMVEQQQLNFYQKPPFPNQPQNQRASMMMPVPSFMHPSQRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N1G0</accession>
    <name>A0A1C7N1G0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_10756</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001372">
        <property type="protein sequence ID" value="OBZ81194.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N1G0"/>
    <dbReference type="InParanoid" id="A0A1C7N1G0"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="63"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="98"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="98"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ81194.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="182" mass="19496" checksum="C701FEE287E82652" modified="2016-11-30" version="1" fragment="single">DKTDSDDSKTDDKTDSVDSKTDSDSKTDSDEKTGSDKTDSDDSKTATTAADSTTTTTIAKGVTTTTTTSSPTTTKKATTTKKATTTKKLTTTKKLTTTKKTTKKTTKKTTKKTTKKTTKKTTKKTTKKTTKKTTKKTTKKTTKKSPACKSGFRGSKNGRGTNGFCCSTKWDCKNACVNGTCH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N344</accession>
    <name>A0A1C7N344_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Mitochondrial carrier</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">A0J61_08892</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000730">
        <property type="protein sequence ID" value="OBZ83059.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N344"/>
    <dbReference type="FunCoup" id="A0A1C7N344">
        <property type="interactions" value="7"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N344"/>
    <dbReference type="InParanoid" id="A0A1C7N344"/>
    <dbReference type="OrthoDB" id="415315at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015095">
        <property type="term" value="F:magnesium ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990616">
        <property type="term" value="P:magnesium ion export from mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="FunFam" id="1.50.40.10:FF:000095">
        <property type="entry name" value="Mitochondrial carrier protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002067">
        <property type="entry name" value="MCP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45667">
        <property type="entry name" value="S-ADENOSYLMETHIONINE MITOCHONDRIAL CARRIER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00926">
        <property type="entry name" value="MITOCARRIER"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 9 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 10" id="KW-0813">Transport</keyword>
    <feature type="repeat" description="Solcar" evidence="9">
        <location>
            <begin position="34"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="9">
        <location>
            <begin position="131"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="9">
        <location>
            <begin position="241"/>
            <end position="351"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="OBZ83059.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="13">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="371" mass="40764" checksum="E2D63440B420FE6A" modified="2016-11-30" version="1">MSQAPESAGQNNRRFPLTPFVVPSITTDGGSKYPPYFDACIAGGIGGSAADFVMHSVDTVKTRLQGQPHTPRVQKYTSMVQAYKLIWKQEGIMRGLYAGVTPAMIGSIPGTTLYFAIYELTKRTLNESNIPEVVSHLMAGSLGDLAASFIYVPSEVLKTRLQLQGRYNNPHFVSGYNYRSTWHATKMIVKYDGFGALFHGFRATILRDVPYSAIQFACYEQFKKIAQNRFKQPGQDLPMGIDMITGSLAGGIAGAITTPLDVMKTLLQTQIGTKKKPISTATVTATASTAAASITHEHPPVKHYSGIIDGMIWNYRNQGMAGLFRGIGPRVFWTSLQSAIMFVVYEQILHIESDLRTKGEWPPTKIAGQLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N3I8</accession>
    <name>A0A1C7N3I8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF7082 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_08302</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000626">
        <property type="protein sequence ID" value="OBZ83651.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N3I8"/>
    <dbReference type="STRING" id="101091.A0A1C7N3I8"/>
    <dbReference type="InParanoid" id="A0A1C7N3I8"/>
    <dbReference type="OrthoDB" id="1751210at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055509">
        <property type="entry name" value="DUF7082"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39463">
        <property type="entry name" value="MEDUSA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39463:SF1">
        <property type="entry name" value="MEDUSA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23305">
        <property type="entry name" value="DUF7082"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF7082" evidence="2">
        <location>
            <begin position="343"/>
            <end position="503"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="149"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="269"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="159"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="272"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="285"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="314"/>
            <end position="332"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF23305"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ83651.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="533" mass="59359" checksum="0E10B1300C50B154" modified="2016-11-30" version="1">MSESYDLPPPNQPPSNDAKLSHPHSTKYRIIDFGPSQGNEGDTFSVSVALQNSLDPSHALRIFFDSCFTTCQFSVDAVNQIITIHTVVPNPDLLSCSDLLRVPVYLALIMQDTQKILDSCLVGCFTYISRKRSSSEYGHLGIGARLNEEAKRSRSDNIQPQSAQPQPSPAAAYTMPTNFASSSSNTGYYELPSTPYVGLPSDQPSSRQREYFENPNILNYYRQSDPTTSFEASYSDTGAPYMTATTNNPPPMMTTQDTAQSSEAYNMMPLLEAPPPPPPHPVQPPLTSSQTPTTSPTTLLPSAAPLQIKPTQPAPISSSNEPYSTSISPTSASGTHPFANLLNKANLRIEGNLEDILKDWTAQEWENQRRLVQFWRRQEGNEVTCKFATFTLPAEKSKQPDMSKIIVVSCIYWREKNDYFITSVDCIYLLENLIGVRFTVEEKNRIRRNLEGYRPLTVSKMKAESADFFKLIMSFPNPKPRNIEKDVKVFPWTTLGVALKKIISKYTASYSSTASVNYDVLSSTTNPSEASNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N3P2</accession>
    <name>A0A1C7N3P2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">pH-response regulator protein palA/RIM20</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">palA</name>
        <name evidence="4" type="ORF">A0J61_08694</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the palA/RIM20 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000694">
        <property type="protein sequence ID" value="OBZ83259.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N3P2"/>
    <dbReference type="STRING" id="101091.A0A1C7N3P2"/>
    <dbReference type="InParanoid" id="A0A1C7N3P2"/>
    <dbReference type="OrthoDB" id="64867at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005768">
        <property type="term" value="C:endosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd09241">
        <property type="entry name" value="BRO1_ScRim20-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.560">
        <property type="entry name" value="alix/aip1 in complex with the ypdl late domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.140.50">
        <property type="entry name" value="alix/aip1 like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.280">
        <property type="entry name" value="alix/aip1 like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025304">
        <property type="entry name" value="ALIX_V_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004328">
        <property type="entry name" value="BRO1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038499">
        <property type="entry name" value="BRO1_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23030">
        <property type="entry name" value="PCD6 INTERACTING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23030:SF39">
        <property type="entry name" value="PROGRAMMED CELL DEATH 6-INTERACTING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13949">
        <property type="entry name" value="ALIX_LYPXL_bnd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03097">
        <property type="entry name" value="BRO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01041">
        <property type="entry name" value="BRO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51180">
        <property type="entry name" value="BRO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BRO1" evidence="3">
        <location>
            <begin position="25"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00038154"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OBZ83259.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="783" mass="88344" checksum="38904C57F8704FDD" modified="2016-11-30" version="1">MFSPSSQKSYTSSIDSTSSSTGATNMLALWPKKTEKITWTPYLREYISNGYAEHPDLYTDDFRVLDELRNDCIYMEVNEKALGRYIKYYAQLVFISAKFPIDVGVDFPWYLACSGESSRMVSHRNMNYEKACILYSIGAVYSQLGIAENRSSTEGIKRACSCFQHAAGCFQHLLDTVVPEMRIGPTVDLSTYALQTLINLMLAQAQECVWQKAAMDQLRDGTIARLALQVASFYEAAYELASNSAIQTVYSKSWIVHMQIKALHFEAAAQFRKSCECISQDKYGQEVARLQLSSDCVRRAFDLAKANRFQSAIMNDLKSLQQIISTNLARAEKDNDMIYLETIPSPSSLPTILKTQMVKATAPPEISDPVSLMMHAEKSNLPHPLIGLPLFQKLVPFAVHQAASVYVDRKERLVKEDIISKLEELTGVYHSSIESLGLPALLATVTSKTGLPDSILKQAAEVRSEGGSQLLYTIWEQVQKASSSNTEILEEAFNALDEEHESDEAMRAKFGDNWRRPESNRLTQQLAAQGQKHRQTLLSAQKADLIVRSKLDTWANIIDVLALTREELENFIPSLDENDQGEPVSSSQDCLLRIKRLVEDMNQNMRVRKELIEKAKRTSSADDISAALLKKAAELTAKSPIVKIEPAQFEDMFIEELRKYDQLIMAVDQQDEQQSIILRQLNEAYHQYQARSKDINNSHGAKAKRDKALQNLTQAYYKFREIKTNLSEGLKFYGEHAKGLVQLCDTCKDYAARRQAESDQMIKSLSMGISNMSISMPESPSRW</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N3P9</accession>
    <name>A0A1C7N3P9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="1">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">ppk13_0</name>
        <name evidence="10" type="ORF">A0J61_08337</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="1"/>
    <dbReference type="EMBL" id="LUGH01000631">
        <property type="protein sequence ID" value="OBZ83618.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N3P9"/>
    <dbReference type="FunCoup" id="A0A1C7N3P9">
        <property type="interactions" value="446"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N3P9"/>
    <dbReference type="InParanoid" id="A0A1C7N3P9"/>
    <dbReference type="OrthoDB" id="248923at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005773">
        <property type="term" value="C:vacuole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032889">
        <property type="term" value="P:regulation of vacuole fusion, non-autophagic"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006624">
        <property type="term" value="P:vacuolar protein processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052239">
        <property type="entry name" value="Ser/Thr-specific_kinases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45998">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE 16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45998:SF2">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE 16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 10" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="9">
        <location>
            <begin position="42"/>
            <end position="329"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OBZ83618.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="334" mass="37885" checksum="45ED09B5B00D013D" modified="2016-11-30" version="1">MSILNDLIGTFNSAVESVTETYNTVSTSSFSNRAIQVNGQTIWITKLLSEGGFSQVYLAENRQKELFAVKAIRCRLDKEAAKTAIREALITDRFQQKGIIQIIDVCMVKEQDGNKTLYIIMPFYKRGNLQDMIEKNFIGGTHISERELLLLFKQICTSIQILAKYTNKRGERIPYAHRDIKPANILLSDDGTMPVLMDFGSAKPARIYIENKKSAIVEQDDAAEHCSMPYRAPELFSVEPDSLLTEKVDIWSLGCTLFAVAYGTSPFEMTINQQGGTLPLAILNRQFSFPYNQQHYSKEFQNFISWMLTTDPDRRPSIDHVLLALDKLMNKTPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N461</accession>
    <name>A0A1C7N461_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">protein-tyrosine-phosphatase</fullName>
            <ecNumber evidence="2">3.1.3.48</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">Dusp2</name>
        <name evidence="9" type="ORF">A0J61_08146</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.48" evidence="2"/>
    <dbReference type="EMBL" id="LUGH01000601">
        <property type="protein sequence ID" value="OBZ83807.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N461"/>
    <dbReference type="STRING" id="101091.A0A1C7N461"/>
    <dbReference type="InParanoid" id="A0A1C7N461"/>
    <dbReference type="OrthoDB" id="273181at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004725">
        <property type="term" value="F:protein tyrosine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043409">
        <property type="term" value="P:negative regulation of MAPK cascade"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd14498">
        <property type="entry name" value="DSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.190.10">
        <property type="entry name" value="Protein tyrosine phosphatase superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.250.10">
        <property type="entry name" value="Rhodanese-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000340">
        <property type="entry name" value="Dual-sp_phosphatase_cat-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029021">
        <property type="entry name" value="Prot-tyrosine_phosphatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001763">
        <property type="entry name" value="Rhodanese-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036873">
        <property type="entry name" value="Rhodanese-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016130">
        <property type="entry name" value="Tyr_Pase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000387">
        <property type="entry name" value="Tyr_Pase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020422">
        <property type="entry name" value="TYR_PHOSPHATASE_DUAL_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10159">
        <property type="entry name" value="DUAL SPECIFICITY PROTEIN PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10159:SF530">
        <property type="entry name" value="DUAL SPECIFICITY PROTEIN PHOSPHATASE DDB_G0271350-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00782">
        <property type="entry name" value="DSPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00581">
        <property type="entry name" value="Rhodanese"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00195">
        <property type="entry name" value="DSPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52799">
        <property type="entry name" value="(Phosphotyrosine protein) phosphatases II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52821">
        <property type="entry name" value="Rhodanese/Cell cycle control phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50206">
        <property type="entry name" value="RHODANESE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00383">
        <property type="entry name" value="TYR_PHOSPHATASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50056">
        <property type="entry name" value="TYR_PHOSPHATASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50054">
        <property type="entry name" value="TYR_PHOSPHATASE_DUAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0904">Protein phosphatase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rhodanese" evidence="8">
        <location>
            <begin position="213"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="domain" description="Tyrosine-protein phosphatase" evidence="6">
        <location>
            <begin position="519"/>
            <end position="666"/>
        </location>
    </feature>
    <feature type="domain" description="Tyrosine specific protein phosphatases" evidence="7">
        <location>
            <begin position="587"/>
            <end position="647"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="31"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="106"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="372"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="412"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="682"/>
            <end position="730"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="145"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="387"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="412"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="429"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="689"/>
            <end position="700"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="705"/>
            <end position="723"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008601"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013064"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OBZ83807.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="730" mass="82403" checksum="AE43E104AD8A4325" modified="2016-11-30" version="1">MKPTVLSTEPTDIRENNSGSFLDLLSAAFQSQTSLSDKEQRPKRTSRQLSSPALRKRSSGNYRISQPQPQQQTPPPPSSDSLLERRRDSNGINYSNCVSVLNEYQQSRQSTAEEGDQLRKIKDKEEDDDDEKPLFTLRKEELPTQPVSPKTSTNRGRIAKRLSATLNAINPIHSNPHTNASSNNLSFLKSIKDTKPIDASLLGQRLKEAQNPLEVEPLMIDMRPLNQYEKSHIRHSINVSVPTLLVKRYRRGVVSNFNLESFITTAEGTDLFRNWLKQFQAQDIQNLPERAQVIVYDEEMAETDMTTATWILMGAIKKNTLAAVHWLQQGYRGFEQWDVTHTYLVGTQFDRLDTPPLPIPSSSSELMKKFKSPLNPPNKLKVPTPMVSRSASTLSAKDNSLTVNVQRRSSLFTLDTSNMRPSKSRTITSIPSRAQPTSSSSSSSLKPQPQPHLSSQRRIPNEVLESISERQNTPTTAIFSPDEVFHTPLESAFPSEEDLMMMTAQDEQTPKTENEYDFVISEIIPNFLYLGPEIATVDQLAGLRSRSIRRILNMAEECDDDVPGLKEHFQYQKVAARDTVEMQNVEGTLRKAVKVIDDSKRHHEPIYVHCKAGKSRSAAAILAYLVLSERWTLKKAYQHIVKMRPNISPNIGFVVELMKLEEGVHGETSNFAGTDWRLIDLTNPPSPDTQREMTRLERAWKRGRSASNASRHLSSSQLSLLSNEGSDEES</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N4F2</accession>
    <name>A0A1C7N4F2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">AN1-type zinc finger protein 2A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">Zfand2a</name>
        <name evidence="7" type="ORF">A0J61_07947</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000570">
        <property type="protein sequence ID" value="OBZ84002.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N4F2"/>
    <dbReference type="STRING" id="101091.A0A1C7N4F2"/>
    <dbReference type="InParanoid" id="A0A1C7N4F2"/>
    <dbReference type="OrthoDB" id="431929at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.1110.10">
        <property type="entry name" value="AN1-like Zinc finger"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035896">
        <property type="entry name" value="AN1-like_Znf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057357">
        <property type="entry name" value="Znf-C2H2_ZFAND2A/B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000058">
        <property type="entry name" value="Znf_AN1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14677">
        <property type="entry name" value="ARSENITE INDUCUBLE RNA ASSOCIATED PROTEIN AIP-1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14677:SF40">
        <property type="entry name" value="CDC48-ASSOCIATED UBIQUITIN-LIKE_ZINC FINGER PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01428">
        <property type="entry name" value="zf-AN1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25403">
        <property type="entry name" value="zf-C2H2_ZFAND2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00154">
        <property type="entry name" value="ZnF_AN1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF118310">
        <property type="entry name" value="AN1-like Zinc finger"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51039">
        <property type="entry name" value="ZF_AN1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="AN1-type" evidence="6">
        <location>
            <begin position="4"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="domain" description="AN1-type" evidence="6">
        <location>
            <begin position="91"/>
            <end position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00449"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51039"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OBZ84002.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="192" mass="21706" checksum="7AED89927D68964D" modified="2016-11-30" version="1">MEFPELGKRCTAKGCNLYDFLPYTCVNCNKVFCQDHFKLQAHQCPSLDDPNFDIRVPICPLCEKPVPSKRGVDPNIRMNEHIQSNCTDLDSKPNNTCRKKGCSTKLLVPMQCADCGLSFCVQHRLAVDHQCKGHTKQQTKPSNTTEKSQRIQQEIAQLQTKLKQGKITDREQLKLAKLLSVKDTKNGKCIVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N4I0</accession>
    <name>A0A1C7N4I0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">A0J61_07944</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000570">
        <property type="protein sequence ID" value="OBZ84003.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N4I0"/>
    <dbReference type="STRING" id="101091.A0A1C7N4I0"/>
    <dbReference type="InParanoid" id="A0A1C7N4I0"/>
    <dbReference type="OrthoDB" id="2441642at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000172">
        <property type="entry name" value="MFS multidrug resistance transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502:SF51">
        <property type="entry name" value="QUINIDINE RESISTANCE PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="41"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="77"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="109"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="171"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="195"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="260"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="297"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="353"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="378"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="441"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="43"/>
            <end position="466"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OBZ84003.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="472" mass="51909" checksum="528DB4AD9E5F6D40" modified="2016-11-30" version="1">MGISEKTTDIVIAEEIPGNSTVNPIQVEESLKNTLSKTRKWFILLIVAMQGFLGPLTSSIYVPAIEQVRRSFNASKTSINITLSLYVFIMGVAPLFWATLSERQGRRIVYLLATMLYILSTIGCGLSHSIGLFISMRAVQAIGASAAQAVGAGTITDLFDVHERGNAMGLFLLGPLVGPVVGPIAGGFINEYMRWRFIFWFLAAMGGLIFLLILFFLPETSSVILQRRALVEKLKDNSDSTLKEVQMDPFWKSMTRPFEFIMKPTVIIATTPYSMAYGFMYFVIASLPHQMAIHYHFASYQIGLSFLANGIGNAVGAYISGKLSDRQINRYLEKEAQEEEKQPGLNLGLESRISPMWIGILLLPLGQLVYGWCMQFSIHFMAALTVGLGVGVVQTPCNTYIVDIYQKHSASAMSVANLLRCISAGCTPLIAPTLIESIGNGWSMTILAILSILSGVCILLIQKFGAKWREVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N4J6</accession>
    <name>A0A1C7N4J6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_09716</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000919">
        <property type="protein sequence ID" value="OBZ82234.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N4J6"/>
    <dbReference type="STRING" id="101091.A0A1C7N4J6"/>
    <dbReference type="InParanoid" id="A0A1C7N4J6"/>
    <dbReference type="OrthoDB" id="10639148at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ82234.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="222" mass="24828" checksum="A54CE172C068EF7A" modified="2016-11-30" version="1">MELPSVLTHKGGMLKAVAELLRPCIENSLKTFSNSEDRKQYASYVPSSTYIRTLLNTNASSNNQRSLDSFVHGPFELDTLMKDLVTEATTEAISIDGSATIEVASDQEGVDNLSDSNHTVSESKIDIAFKRVFDENTNMVNKDSFKRRVPSSYELLPSLESSFLSFGPLKCSKSARTLFDNLAWKQALSILKTVKLDYASDLLGVQLYYKTGMRDKFWLDLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N5C4</accession>
    <name>A0A1C7N5C4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Host cell factor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">Hcf</name>
        <name evidence="4" type="ORF">A0J61_07626</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000525">
        <property type="protein sequence ID" value="OBZ84323.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N5C4"/>
    <dbReference type="STRING" id="101091.A0A1C7N5C4"/>
    <dbReference type="InParanoid" id="A0A1C7N5C4"/>
    <dbReference type="OrthoDB" id="10250130at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd09917">
        <property type="entry name" value="F-box_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.80">
        <property type="entry name" value="Kelch-type beta propeller"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015915">
        <property type="entry name" value="Kelch-typ_b-propeller"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46093">
        <property type="entry name" value="ACYL-COA-BINDING DOMAIN-CONTAINING PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46093:SF18">
        <property type="entry name" value="FIBRONECTIN TYPE-III DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24681">
        <property type="entry name" value="Kelch_KLHDC2_KLHL20_DRC7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117281">
        <property type="entry name" value="Kelch motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0880">Kelch repeat</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="405"/>
            <end position="491"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="551"/>
            <end position="589"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="429"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="459"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="475"/>
            <end position="491"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="564"/>
            <end position="586"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OBZ84323.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="603" mass="68559" checksum="2C66386238A58DA9" modified="2016-11-30" version="1">MSATNIFDLSLDIKYIILDYLDNMSLAHLAQTCTYFGLLVRKVMSFRNGQVTIADHMMPKPPPFLNYRAGVSIGSTFYMPFINESPFCYCYDLDHHIWTTRKLNLIDMAHIQPQITCASVIGNKIYLVGGRLLNSYILSNAVIEIDTDNFNTRIIKDAEGSPPRPRHEHSVDAVADRFLVVFGGLCYNSVGENDVYVYDKFDNRWFVPPVTGHLPHLRFGHASAVIGTDLYIHGGAQLDNDSSYIVYDDLYKLDCKEWVWYKYEHPEVERYLRNQDVSQGGPSSHREHLISTNGDSPYDRFQSYMCNYGHKLIIFGGHSIREDEDDNEILCSYSLDELCVFNVKRNAWSLFHASVMRDGPLEEEDSKKTEESLTVSDMSIAPVMLDGYGIRIYIFAGHKAAEEPRSSDQLMETDNSSHSFDSNHHSDQHYTTLPSITEQIQSDGDDTYSSSQSYTAEPKTIEQTDGLRFEDNDNKPTNSDQGDLRTPNHNGISTHVEELFQSVDPDMINRRVENNSVGANEESEIIAHHNASHAHSSRKDSRRRPSISVIHRNHRSNEEDPYRSLPASSSSHSSLSSSNSPNPWKSNRQRKITPCSIVLELFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N5V9</accession>
    <name>A0A1C7N5V9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">DEK-C domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">A0J61_07557</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000516">
        <property type="protein sequence ID" value="OBZ84391.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N5V9"/>
    <dbReference type="STRING" id="101091.A0A1C7N5V9"/>
    <dbReference type="InParanoid" id="A0A1C7N5V9"/>
    <dbReference type="OrthoDB" id="370884at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030428">
        <property type="term" value="C:cell septum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004100">
        <property type="term" value="F:chitin synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006031">
        <property type="term" value="P:chitin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031505">
        <property type="term" value="P:fungal-type cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004835">
        <property type="entry name" value="Chitin_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014876">
        <property type="entry name" value="DEK_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22914">
        <property type="entry name" value="CHITIN SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22914:SF13">
        <property type="entry name" value="CHITIN SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03142">
        <property type="entry name" value="Chitin_synth_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08766">
        <property type="entry name" value="DEK_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109715">
        <property type="entry name" value="DEK C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51998">
        <property type="entry name" value="DEK_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="7"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="36"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="64"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="domain" description="DEK-C" evidence="8">
        <location>
            <begin position="235"/>
            <end position="290"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51998"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OBZ84391.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="292" mass="33318" checksum="C2297ECE27BBECB2" modified="2016-11-30" version="1">MRFVVILDLLSTLVMPAVVCYLGFLIYKLATNAGQVPFISIITLCGVYGLQALIFIIHRKWEHIGWMIVYILAIPLFSFFIPIYAFWHFDDFSWGNTRLVMGEDGQKKALPADEGKFDPKTIPLKKWCDHENELWEAGSTVSKGTTITSSTTRRSIPVLNNGYMSTSNLSPLAMTPSGLYNADNTSFRYSSQNLTVLNQPSVFNMTTNPMPPASVYSEGIVHTMDYTNMMDGIYQPTDEEIRREVQRITSTADLMTMTKKQVREQLSRHFGINMAYRKDFISYCIEESLKYQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N653</accession>
    <name>A0A1C7N653_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">RNA polymerase II transcription factor B subunit 3</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">RNA polymerase II transcription factor B 38 kDa subunit</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">RNA polymerase II transcription factor B p38 subunit</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="primary">TFB3</name>
        <name evidence="12" type="ORF">A0J61_07441</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000502">
        <property type="protein sequence ID" value="OBZ84501.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N653"/>
    <dbReference type="FunCoup" id="A0A1C7N653">
        <property type="interactions" value="338"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N653"/>
    <dbReference type="InParanoid" id="A0A1C7N653"/>
    <dbReference type="OrthoDB" id="5963at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070985">
        <property type="term" value="C:transcription factor TFIIK complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061575">
        <property type="term" value="F:cyclin-dependent protein serine/threonine kinase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006289">
        <property type="term" value="P:nucleotide-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001174">
        <property type="term" value="P:transcriptional start site selection at RNA polymerase II promoter"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.40.10:FF:000037">
        <property type="entry name" value="Cdk-activating kinase assembly factor MAT1, centre"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004575">
        <property type="entry name" value="MAT1/Tfb3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015877">
        <property type="entry name" value="MAT1_centre"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017907">
        <property type="entry name" value="Znf_RING_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00570">
        <property type="entry name" value="cdk7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12683">
        <property type="entry name" value="CDK-ACTIVATING KINASE ASSEMBLY FACTOR MAT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12683:SF13">
        <property type="entry name" value="CDK-ACTIVATING KINASE ASSEMBLY FACTOR MAT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06391">
        <property type="entry name" value="MAT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17121">
        <property type="entry name" value="zf-C3HC4_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00518">
        <property type="entry name" value="ZF_RING_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 9" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="11">
        <location>
            <begin position="32"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="160"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="168"/>
            <end position="186"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022257"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00029873"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00033277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="OBZ84501.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="332" mass="37755" checksum="7609039BDBF2B1BD" modified="2016-11-30" version="1">MTNTLKHQTLMIGKTGSSVVSFQASREEDAQCPVCKSDKYLTPNLKLLVSPCFHKMCESCIDRLFGAGPAPCPICLQVLRKNQFMSQIFEDLAVEKEVRIRKRAARVFNKRPEDFSSLRAYNDYLEMVEDITFNLMNEVDVAETEAKIAAYEQENKDSIAANQARSVNEQRVRSYQDELDKQEREQKHKEYLQQLEDERRQKELEKSDIIAELANSNKSAQSVIQSRQATALKRSSALKQSSTTTKSSMPSWISSVMDSDHAAKEAESLFDPYELAYEYTSGYVVRESYQDPTVDYLNNNKQARAGGYTARFAHQRALMSAFTGVLCSPLQD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N682</accession>
    <name>A0A1C7N682_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_07306</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000486">
        <property type="protein sequence ID" value="OBZ84643.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N682"/>
    <dbReference type="InParanoid" id="A0A1C7N682"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ84643.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="201" mass="22995" checksum="47F690C9F788AD0B" modified="2016-11-30" version="1">MKQDFIDFNKSSNSSTPSEEPEADLCICLPYIMAIICNAVIKSENADPQQISQDFVFSFCNTVIHANVRISASTTTNSLLWLSQTEPEFQPLTETKTVSAEDVGFASDNFHYRHKLALLKEKSPQIIEAKPALSHRNFITIMNEDVWNTYRCLRGNKNVSRSFCQCSKINKGDTKREMYMKKLKDHTCVRERLCLSPDTRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N6I1</accession>
    <name>A0A1C7N6I1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 7">Mediator of RNA polymerase II transcription subunit 7</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">MED7B</name>
        <name evidence="8" type="ORF">A0J61_07292</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Component of the Mediator complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the Mediator complex subunit 7 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000485">
        <property type="protein sequence ID" value="OBZ84651.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N6I1"/>
    <dbReference type="STRING" id="101091.A0A1C7N6I1"/>
    <dbReference type="InParanoid" id="A0A1C7N6I1"/>
    <dbReference type="OrthoDB" id="10253553at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070847">
        <property type="term" value="C:core mediator complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016592">
        <property type="term" value="C:mediator complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003712">
        <property type="term" value="F:transcription coregulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.1520">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037212">
        <property type="entry name" value="Med7/Med21-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009244">
        <property type="entry name" value="Mediatior_Med7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044888">
        <property type="entry name" value="Mediatior_Med7_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21428">
        <property type="entry name" value="MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21428:SF11">
        <property type="entry name" value="MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05983">
        <property type="entry name" value="Med7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140718">
        <property type="entry name" value="Mediator hinge subcomplex-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0010">Activator</keyword>
    <keyword evidence="6 7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7" id="KW-0804">Transcription</keyword>
    <keyword evidence="4 7" id="KW-0805">Transcription regulation</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009994"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00020631"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU364060"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OBZ84651.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="183" mass="21799" checksum="AD7CED5BD60C0C9C" modified="2016-11-30" version="1">MEEQQSARSAWPDPPTYYKRYTTENLELLKQAQKADDYESTLDFPLKQLEPPLPPTDDYSVFDQKWQIQDRLPTLEELQVKQLYPENQDIDRVKELKKLNRSLVTQFLQLLDVLVEKPEEFGKHIENISHLFINMHHILNAYRPHQARETLRLLMENQLTKKRQQTAALKAQSKEALEFLQRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N6J4</accession>
    <name>A0A1C7N6J4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_07200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000474">
        <property type="protein sequence ID" value="OBZ84752.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N6J4"/>
    <dbReference type="InParanoid" id="A0A1C7N6J4"/>
    <dbReference type="OrthoDB" id="3936150at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="94"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="135"/>
            <end position="155"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ84752.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="168" mass="19635" checksum="77E1CF620E7E4BDE" modified="2016-11-30" version="1">MVLIKQIDTFHCFTIENALHFFLEKEDRKSVKSPRWLYERLLGEIFQSSLVFIETDMKIEHGCNVLQHNKSQVSKNYFEELCLTEIRQYTSCCLILLFVPSWKLLLTGVNYILYDIKEQSTDTSCMVNSLRPIQFGWSVWVSMVQIFNLAMPYLVDAVSNRGAATKVY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N6N8</accession>
    <name>A0A1C7N6N8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Tc1-like transposase DDE domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_07230</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000478">
        <property type="protein sequence ID" value="OBZ84717.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N6N8"/>
    <dbReference type="STRING" id="101091.A0A1C7N6N8"/>
    <dbReference type="InParanoid" id="A0A1C7N6N8"/>
    <dbReference type="OrthoDB" id="2274210at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ84717.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="248" mass="28803" checksum="A2F699A9B5793924" modified="2016-11-30" version="1" fragment="single">GGITTEDGTETIDYIIEEGEEFNLRNLTNLSEYNDCQPVPIELDAEDENLESRISLVIEKVNKTIADKVGNVRSYMSYTDDQKTLFLYYLKIKFFSTAKAAEYAGIAERTAQTWAKRIRTEPGWNIYEKQTNKSSWAMSQLQEPRKLHILELFDNKPYTTTDEVVDSLTKAFEGFMLKQSTVNSFILHECNLTIKRLQRQPKARNNPARIQARYDWVMKYDSSDMDFLRNCIFIDESGFDINMRPSHG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N6W9</accession>
    <name>A0A1C7N6W9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Protein MGA2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">MGA2_0</name>
        <name evidence="6" type="ORF">A0J61_07118</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000464">
        <property type="protein sequence ID" value="OBZ84832.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N6W9"/>
    <dbReference type="FunCoup" id="A0A1C7N6W9">
        <property type="interactions" value="202"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N6W9"/>
    <dbReference type="InParanoid" id="A0A1C7N6W9"/>
    <dbReference type="OrthoDB" id="71307at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051059">
        <property type="term" value="F:NF-kappaB binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071356">
        <property type="term" value="P:cellular response to tumor necrosis factor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00102">
        <property type="entry name" value="IPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002909">
        <property type="entry name" value="IPT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051070">
        <property type="entry name" value="NF-kappa-B_inhibitor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057962">
        <property type="entry name" value="SPT23_MGA2_DBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46680">
        <property type="entry name" value="NF-KAPPA-B INHIBITOR ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46680:SF3">
        <property type="entry name" value="NF-KAPPA-B INHIBITOR CACTUS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25603">
        <property type="entry name" value="SPT23_MGA2_DBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01833">
        <property type="entry name" value="TIG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00429">
        <property type="entry name" value="IPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="E set domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="IPT/TIG" evidence="5">
        <location>
            <begin position="424"/>
            <end position="508"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="615"/>
            <end position="647"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="214"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="302"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="214"/>
            <end position="227"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OBZ84832.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="769" mass="86548" checksum="7A3FA6E6D031AAD9" modified="2016-11-30" version="1">MFSYCTTNEQYINPIQTLNETDLRDLFEPNANLSFLQTLSPAFEASSPRTFDSLSDNASDSPNSQYVDDLKEFEPIVHEPNNDFFFNFLNGDIQSEKSMPLKDDSEHLEIRILGVPKTGAKSRVETQIKLCIQLMTKDEKKVLDWSHIRLSESMLARSKLRRNQQKQQSKAIDGPMLSMVSDESKVLDLEAKVICASNTDHPIRMCASCVGRERRRAERTKDGKPKSDSSLLPKDIEAERNRILLFNCNTLVDFSSGDAILPSRITCYCRHHDEKVGFRISFTMKDYKGCVVATGISPPIMITDDHKGSKQKGYRKRSRDESISSLPHTPAISRRSSMTADESAMLMEEDDCSEEDVHTRTPTNFESTYLISNDFPPIQPELSVFPTASQSEEWPYNRRRRTVKGFASADMSANILINSMLDTVPQLDRLVPSQGPTYGGIEVTLLGSGFYRGLTCMFGEHAATTIHWNANTMVCVLPPATQTGPVVVSFKEHPLVLEGQDVAIFIYYDASDRALLELALQVVGLKMTGKLQDAKHVAMRIVQGDQQDSYQSSVLEAVERSDTAVDYTQVNTNGHTLLHLAVLLNNEALVKAIIKSYQCRPKEERLRLLNMQDRNKMTALHFACQLKSSNLVRILLYAGASANLASNWGLPSVSCGKEDSDLLDLLDLYQKNLTWRELVSRKHDHMSRLFSGLSITDSIHVIASTDLVLLDINTVDHRLYRSRMPILCDKPHIQPFFDFLVIAALFGLQAHGYFGLPKLEMLCNSFLSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N701</accession>
    <name>A0A1C7N701_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Tc1-like transposase DDE domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_07173</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000470">
        <property type="protein sequence ID" value="OBZ84778.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N701"/>
    <dbReference type="InParanoid" id="A0A1C7N701"/>
    <dbReference type="OrthoDB" id="2266637at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ84778.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="91" mass="10910" checksum="B1E2B29A284EE72C" modified="2016-11-30" version="1">MPNLKSVAEMSDLKFLEEALYFVDKHDRVRDFYLFMNNAPIHSSKQISELIESRIKHKILWDLKTLEERIIEAAYEIPLRQLRNIIKLSKH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N7J9</accession>
    <name>A0A1C7N7J9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Nucleoporin SEH1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">SEH1L</name>
        <name evidence="12" type="ORF">A0J61_07354</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nuclear pore complex</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the WD repeat SEC13 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000491">
        <property type="protein sequence ID" value="OBZ84596.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N7J9"/>
    <dbReference type="FunCoup" id="A0A1C7N7J9">
        <property type="interactions" value="793"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N7J9"/>
    <dbReference type="InParanoid" id="A0A1C7N7J9"/>
    <dbReference type="OrthoDB" id="5566198at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031080">
        <property type="term" value="C:nuclear pore outer ring"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035859">
        <property type="term" value="C:Seh1-associated complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005198">
        <property type="term" value="F:structural molecule activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034198">
        <property type="term" value="P:cellular response to amino acid starvation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051028">
        <property type="term" value="P:mRNA transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:1904263">
        <property type="term" value="P:positive regulation of TORC1 signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037363">
        <property type="entry name" value="Sec13/Seh1_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11024">
        <property type="entry name" value="NUCLEAR PORE COMPLEX PROTEIN SEC13 / SEH1 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11024:SF3">
        <property type="entry name" value="NUCLEOPORIN SEH1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0509">mRNA transport</keyword>
    <keyword evidence="8" id="KW-0906">Nuclear pore complex</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-0653">Protein transport</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="8" id="KW-0811">Translocation</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <keyword evidence="4 10" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="10">
        <location>
            <begin position="9"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="10">
        <location>
            <begin position="479"/>
            <end position="524"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="10">
        <location>
            <begin position="560"/>
            <end position="591"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="165"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="225"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="341"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="398"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="524"/>
            <end position="544"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="180"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="345"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="376"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="404"/>
            <end position="422"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004567"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022816"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023132"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="OBZ84596.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="613" mass="67975" checksum="B53DBF8E9D90CD41" modified="2016-11-30" version="1">MASSLTKFDTDHEDLIHDVSYDFYGKRLVTCSSDQRLKVWDFIERLDASVWELNDAWKAHDSSILKAIWARPEYGQVIASCSFDRQVKIWEEQLVEPRNSQKRWAERFRLVESRGAVLDIAFSPSQNSLRLATCSSDGIVRIYEALEPTNLAQWSQMEEFEIASNQIGPNDHKGTPSGISQLRQQSQQQHQQQQVQQQQQSQVQPLKQLSLLQAQLSQASQQSSQPSLQQTLQQQSSQQMPLLQQQQQQQSIPIHSSQSAHQSNLSQALQPSQTQQSQQQLQPQLQQQQSQPLDSFYQVNTQQSQQQQQAQTQQSLLLQQAQQPSQLPYPSAQTTLINHAFGQPSHTNSTSSSASSTTSHDVSTPGVPDTLNMGVPTTSNPSTTAAPEVVSTVVTATGATTSANPGTGQGVSPGSSANISQTTAANHTHRLIDADSGYCLDWCPNRSSTAMMVIGLGKEVGARIFKHDGHNRWIPAEFLPGHTDLVHDVSWAPSMARSYQLIATASKDGMVRIFRLTEQTVPAQKPQQTVQRGRSAFSPAGTPTQNTNTKVFHIEMIACFDDHKAEVWRVEWNVTGTILSSSGDDGRLRLWTTGYDGQWRQMASIAANSQIPN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N7U8</accession>
    <name>A0A1C7N7U8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_06751</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000422">
        <property type="protein sequence ID" value="OBZ85200.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N7U8"/>
    <dbReference type="InParanoid" id="A0A1C7N7U8"/>
    <dbReference type="OrthoDB" id="2272415at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ85200.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="276" mass="31763" checksum="51DCFD555FA21437" modified="2016-11-30" version="1">MNTRHLTVDSFDEVQGKLILPSFWELNEPCDWKPINYLSELYKSDPTLERSSAHRHLLKDVETLKKLVVPGTVAETMLNIMYCFNSSKSGKTALKKFYEHVDVFKSSGLNERISKEKVRSTLKLDVALEEEKRVQKKLKTCDTSKIDDNLATMPNSTKEEDGDEKIDNIWLLWKKFLNEAEINNYLPSLSPEKHGVIWCGPGVSCRSSFPRGLYSQTQYQLAALEQYSICSRFKKIVKATLQKTNRIDMIDCIETLRSTRSNLGEKKLLVELFTLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N806</accession>
    <name>A0A1C7N806_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF3020 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_06762</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000424">
        <property type="protein sequence ID" value="OBZ85187.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N806"/>
    <dbReference type="STRING" id="101091.A0A1C7N806"/>
    <dbReference type="InParanoid" id="A0A1C7N806"/>
    <dbReference type="OrthoDB" id="5595797at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021386">
        <property type="entry name" value="SPP41_DUF3020"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11223">
        <property type="entry name" value="DUF3020"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF3020" evidence="2">
        <location>
            <begin position="159"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="91"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="152"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="210"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="291"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="338"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="409"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="22"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="91"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="108"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="152"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="168"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="338"/>
            <end position="357"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF11223"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ85187.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="472" mass="51812" checksum="7BEA38BE363E1CF4" modified="2016-11-30" version="1">MSQEEHSLEKELQKEKTEKESMTSPMDTTVPSETNDTGEETSLVSATLPQQQENLAAINQLQLAHAALSGADDFPFLTNFENSMDVIATSDVPTNGTNTPASLHTLGQDPTTVQSPQSQQETSGQPTKQQNIQPTADLSQLPTELLKRELMNQKVRADNRERKKRWRQQNEERNKDNDLRCRVNKRAHKLFGKEDSEHKKKWIEEEFLKRQQKRKDKERRKGLVDDSLGGHAEGALNTNSGLDLAALAQHLAPQQSLTDASYLTLLCNNLGIPAAARNLLGTMNTTGHTVVENSESTVPPLSAPPVEQDTLKDEKDPRLQPFPFQILELLQQLQHYQGSDTTSNNNNTNSGGESSTSHDFSLAPSYGHLGGIGERPEEKLVALLATTIQQAANVAAAAQVRDSLLNNEADGTDMNMTGLSNHHGSDSSSKDIAIAPAAENTNDDTAQNNSNNAEFPMDAVLTLMQLNAGWRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N884</accession>
    <name>A0A1C7N884_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Endoplasmic reticulum transmembrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="primary">SPAC9E9.04</name>
        <name evidence="15" type="ORF">A0J61_06616</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">May play a role in anterograde transport of membrane proteins from the endoplasmic reticulum to the Golgi.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 11">Endoplasmic reticulum membrane</location>
            <topology evidence="1 11">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the BCAP29/BCAP31 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000408">
        <property type="protein sequence ID" value="OBZ85332.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N884"/>
    <dbReference type="FunCoup" id="A0A1C7N884">
        <property type="interactions" value="223"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N884"/>
    <dbReference type="InParanoid" id="A0A1C7N884"/>
    <dbReference type="OrthoDB" id="435607at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006888">
        <property type="term" value="P:endoplasmic reticulum to Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070973">
        <property type="term" value="P:protein localization to endoplasmic reticulum exit site"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008417">
        <property type="entry name" value="BAP29/BAP31"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040463">
        <property type="entry name" value="BAP29/BAP31_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041672">
        <property type="entry name" value="Bap31/Bap29_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12701">
        <property type="entry name" value="BCR-ASSOCIATED PROTEIN, BAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12701:SF20">
        <property type="entry name" value="ENDOPLASMIC RETICULUM TRANSMEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05529">
        <property type="entry name" value="Bap31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18035">
        <property type="entry name" value="Bap31_Bap29_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 12" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5 11" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="6 11" id="KW-0931">ER-Golgi transport</keyword>
    <keyword evidence="10 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 11" id="KW-0653">Protein transport</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 11" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="44"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="domain" description="BAP29/BAP31 transmembrane" evidence="13">
        <location>
            <begin position="1"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="domain" description="Bap31/Bap29 cytoplasmic coiled-coil" evidence="14">
        <location>
            <begin position="159"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="12">
        <location>
            <begin position="146"/>
            <end position="204"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007956"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU367026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF05529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF18035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="OBZ85332.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="211" mass="24934" checksum="603040AA2ACCFEA6" modified="2016-11-30" version="1">MTIYYTAVFLILMVEMVAFCLLVIPLPSRWRRAILKFASTSPVVARAISTLKIVFGFIFVLFIDAVSRLQRIDQDGASDGHHHDYSYETNLKARKFYAQRNLYLTGFTLFLSLILERTSTLLIQMLKHDEELEYAKKENLSSQEDQKRLVEMERTYESKIKNLREELMVLQQEDRDFENLKKQVEQQTSEYHRLMDEHKKLESTLNVKKTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N8C3</accession>
    <name>A0A1C7N8C3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative J domain-containing protein C3E7.11c</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_06760</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000423">
        <property type="protein sequence ID" value="OBZ85198.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N8C3"/>
    <dbReference type="STRING" id="101091.A0A1C7N8C3"/>
    <dbReference type="InParanoid" id="A0A1C7N8C3"/>
    <dbReference type="OrthoDB" id="552049at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018253">
        <property type="entry name" value="DnaJ_domain_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026894">
        <property type="entry name" value="DnaJ_X"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44924">
        <property type="entry name" value="DNAJ SUBFAMILY A MEMBER 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44924:SF1">
        <property type="entry name" value="DNAJ SUBFAMILY A MEMBER 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14308">
        <property type="entry name" value="DnaJ-X"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00625">
        <property type="entry name" value="JDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00636">
        <property type="entry name" value="DNAJ_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="J" evidence="2">
        <location>
            <begin position="86"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="53"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="196"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="57"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="198"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="210"/>
            <end position="221"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ85198.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="412" mass="46954" checksum="72122C41F738F55E" modified="2016-11-30" version="1">MTKIFESRKPEPYIKTSCKKCITPIEFLPEGQPVGQAVSVKCWSCNQTETYTVTDPNSHKDNKSSTADKPKTSRKRGTDQKPLSTEYYDLLGVEVTADQDAIKKAYRKLAIRYHPDKNQNDPAAGEKFKQISEAYQILSDPKLRKRYNELGDQKDVKPEDGFVDPEEFFRQSYGGDRFVDIIGEIAIGKDMKDAMETATEEGQELSPEEQAERETQRAEAEQERAAVREKRIEALSEKLIERLEKIKLVDEDHFVKSVEQEAQELKQENHGVQLLHVIGNIYSIKASQYSNRKSVFGLGGMYYSIREKGYIFGQTVNTLRTAYDLQSTFDQLQKAEEKGLSEEEKAKLQQTAEEKGMEALWKGSKLEIEGVLRDVCDQVLDDPKCSKQDMTYRLRALTLIGAIYQSVTPLES</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N8L7</accession>
    <name>A0A1C7N8L7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">mannan endo-1,4-beta-mannosidase</fullName>
            <ecNumber evidence="3">3.2.1.78</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">MAN9</name>
        <name evidence="7" type="ORF">A0J61_08268</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Random hydrolysis of (1-&gt;4)-beta-D-mannosidic linkages in mannans, galactomannans and glucomannans.</text>
            <dbReference type="EC" id="3.2.1.78"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the glycosyl hydrolase 5 (cellulase A) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.78" evidence="3"/>
    <dbReference type="EMBL" id="LUGH01000621">
        <property type="protein sequence ID" value="OBZ83684.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N8L7"/>
    <dbReference type="STRING" id="101091.A0A1C7N8L7"/>
    <dbReference type="InParanoid" id="A0A1C7N8L7"/>
    <dbReference type="OrthoDB" id="406631at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016985">
        <property type="term" value="F:mannan endo-1,4-beta-mannosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001547">
        <property type="entry name" value="Glyco_hydro_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045053">
        <property type="entry name" value="MAN-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31451">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31451:SF40">
        <property type="entry name" value="GLYCOSIDE HYDROLASE FAMILY 5 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26410">
        <property type="entry name" value="GH5_mannosidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glycoside hydrolase family 5" evidence="6">
        <location>
            <begin position="2"/>
            <end position="415"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001678"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012706"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF26410"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OBZ83684.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="418" mass="48636" checksum="8C05B98CC120A9E8" modified="2016-11-30" version="1">MTFVTIKDTRFYLHHQVYPIKSANYWQGMNLGASEENGGDRARLCQELDQMKAMGVNNLRVMASSEGPDDQPYRMRPSLQPSPGVYNQAIFEGLDYLLDQMGQRNMTAVMTLNNFWQWSGGFGQYVAWITQEAIPYPIKEYDPFVEFCQRFYDDPTIREQVKALFYAHIRTVQTRVNRFNQKIYHQDPVIMSWQIANEPQSGPQWWYRETARFIKEGAPYQLISAGIESKEDQADFNHAHDNAYVDYCTCHCWVENWGQYDPNEPTGISLDHAKQFAIEFIRTRAQWSQEINKTIILEEFGMARDGWRNPSDGYKYLPSTPTQHRDAYYATLFRQIESLPIYAGDGFWAYGGLGRSTDKPNQFDMVWLGGNHHHHHTKEGLSTGLDPPHEPKGWYSVYDTDSTVKIIQGHFKQLDQRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-06-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N9I0</accession>
    <name>A0A1C7N9I0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_06663</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000413">
        <property type="protein sequence ID" value="OBZ85286.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N9I0"/>
    <dbReference type="InParanoid" id="A0A1C7N9I0"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ85286.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="67" mass="7816" checksum="EC0611951241DB60" modified="2016-11-30" version="1">MRTANWKISFSTKKEYLKGLNGTLWRKLNALLVFFFAMQIWSHEHSTREDKGCATYELCDQESPSGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N9K7</accession>
    <name>A0A1C7N9K7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">UDP-N-acetylglucosamine transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">SLC35A3_0</name>
        <name evidence="6" type="ORF">A0J61_06338</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000378">
        <property type="protein sequence ID" value="OBZ85618.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N9K7"/>
    <dbReference type="FunCoup" id="A0A1C7N9K7">
        <property type="interactions" value="46"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N9K7"/>
    <dbReference type="InParanoid" id="A0A1C7N9K7"/>
    <dbReference type="OrthoDB" id="408493at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015165">
        <property type="term" value="F:pyrimidine nucleotide-sugar transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037185">
        <property type="entry name" value="EmrE-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007271">
        <property type="entry name" value="Nuc_sug_transpt"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00803">
        <property type="entry name" value="nst"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10231">
        <property type="entry name" value="NUCLEOTIDE-SUGAR TRANSMEMBRANE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04142">
        <property type="entry name" value="Nuc_sug_transp"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005799">
        <property type="entry name" value="UDP-gal_transpt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103481">
        <property type="entry name" value="Multidrug resistance efflux transporter EmrE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="37"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="119"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="145"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="185"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="241"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="281"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="307"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="333"/>
            <end position="350"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OBZ85618.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="352" mass="39237" checksum="2505D4E3C0D3A470" modified="2016-11-30" version="1">MDKTSLKYLSLFVLVLQNSALILTMRYTRASVPEDELYLASTAVLLSEVLKSLVCLAVIYSLLPSRIRSLSNLNLFLYQEFVLRWSESIKLAIPAILYLIQNNLQYVAATHLDAATFQVTYQLKILTTAFFSVILLHRRLSSTKWIALGILTAGIALVVLPKNSLSQWLGPDDREQETSRIGNQYNMKGFIAVLFACILSGIAGVYFEKIVKQAHKEQDIEGYQTEPVVLLNIPVDDKMQLWIRNIQLSVFSVLLGGLFVVGLQDGARIIQDGFFQHYSTLTWVVIFIQAGGGLIVGLVVRYADNILKGFATSISIILSSLLSVWLFGSQVNMVFGIGACLVIYATFMYGRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N9L3</accession>
    <name>A0A1C7N9L3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">L-sorbose 1-dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">SDH</name>
        <name evidence="7" type="ORF">A0J61_06594</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 5">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the GMC oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000405">
        <property type="protein sequence ID" value="OBZ85359.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N9L3"/>
    <dbReference type="STRING" id="101091.A0A1C7N9L3"/>
    <dbReference type="InParanoid" id="A0A1C7N9L3"/>
    <dbReference type="OrthoDB" id="269227at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016614">
        <property type="term" value="F:oxidoreductase activity, acting on CH-OH group of donors"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.560.10">
        <property type="entry name" value="Glucose Oxidase, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012132">
        <property type="entry name" value="GMC_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000172">
        <property type="entry name" value="GMC_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007867">
        <property type="entry name" value="GMC_OxRtase_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11552:SF147">
        <property type="entry name" value="CHOLINE DEHYDROGENASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11552">
        <property type="entry name" value="GLUCOSE-METHANOL-CHOLINE GMC OXIDOREDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05199">
        <property type="entry name" value="GMC_oxred_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00732">
        <property type="entry name" value="GMC_oxred_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000137">
        <property type="entry name" value="Alcohol_oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00624">
        <property type="entry name" value="GMC_OXRED_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glucose-methanol-choline oxidoreductase N-terminal" evidence="6">
        <location>
            <begin position="271"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="233"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR000137-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS00624"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OBZ85359.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="551" mass="61138" checksum="BDC494F26D807A99" modified="2016-11-30" version="1">MPRIEPSKIANKIFDYVIIGGGTAGCVLANRLSSNGRYHVLVLEAGKSTPDLLEVRIPLFNSKLKNSPADWQFKSAVQEHANQRQIGVPLGKLLGGSSAFNACIAHRCSPSDYDGWNVPEWSYGQLAQYFRKAETFHDTADVSPTLHGTTGSFHVSQMNRDNQPIGLHFKQACKKKLGLEEHYDMTDLPCQIGVTGLQASIYQGQRVSTGATYLPLEIQQERDNLSIALGCQVNRLVLDEQHRVTHVEFRDIEQDTVHQVQVGQEAILSAGAILSPVLLLQSGLGPKEELEEIGIEPLVDLPGVGKNLQNHWRVPLVHETKTADMSLHQGIFQLQEASLERALKQHDGPLTELWPDAVAFMKIPDAPDNSSSQENTPQIELFAGGLALCRELPKLKHLNCATLLMVYVAPFSRGSVKLDKAKAPLIDFGLLKDERDMECLEKGLKLSMSIAQDEDYQRHCVKEWLMYPENEQEIQTYIKDNIDTLHHYAGTCKMGPKEDRMAVVDHHLKVHGVNGLRVVDASFFPKVPAGQTCFPVIACAERAADLILQGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NAL7</accession>
    <name>A0A1C7NAL7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_06280</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000372">
        <property type="protein sequence ID" value="OBZ85666.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NAL7"/>
    <dbReference type="InParanoid" id="A0A1C7NAL7"/>
    <dbReference type="OrthoDB" id="5340906at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="104"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="106"/>
            <end position="118"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ85666.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="126" mass="14379" checksum="3E1835CAF6AF796B" modified="2016-11-30" version="1">MLYSLCQKVESDAIPKLRTVGLQFGKFNLEAYCMDMPKGYCARVTKTSTICFDEDEFVDTFVKWFSPANKALPVCEETATAITENKKRNDDNDFVIPFESDEMEYPLCLPSPSHLSSDSNKKRRLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NAM4</accession>
    <name>A0A1C7NAM4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Glycosyltransferase 61 catalytic domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">A0J61_05784</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000323">
        <property type="protein sequence ID" value="OBZ86163.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NAM4"/>
    <dbReference type="STRING" id="101091.A0A1C7NAM4"/>
    <dbReference type="InParanoid" id="A0A1C7NAM4"/>
    <dbReference type="OrthoDB" id="529273at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049625">
        <property type="entry name" value="Glyco_transf_61_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007657">
        <property type="entry name" value="Glycosyltransferase_61"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20961">
        <property type="entry name" value="GLYCOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20961:SF38">
        <property type="entry name" value="PROTEIN O-LINKED-MANNOSE BETA-1,4-N-ACETYLGLUCOSAMINYLTRANSFERASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04577">
        <property type="entry name" value="Glyco_transf_61"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="2" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyltransferase 61 catalytic" evidence="9">
        <location>
            <begin position="136"/>
            <end position="333"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF04577"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OBZ86163.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="480" mass="54631" checksum="F3BA94B0F573D12F" modified="2016-11-30" version="1">MIQLAKIKRRLHYIILAGVGVCFLYYLWLFSKGEPIHESTWTCRGTGRQQICEFNNLCVDRYRGPFIVSDKEPPRVNVVNADEAGDIWFQPTRMTPHRLLRARHIPETLFVYGLYAPYHFSHMLYNGLMPLYSTIQSYGASNQVWTMRVGTYQNKHTPISIISSPALEEGHDIVLEGADVLTDQQALPPHQTVCFSKAIVGSGNRCSHAYCENQIPAAHYASFKQVVLDQTAAPNNPCAASQIVYKEAGQYRVGILNRKRSRHITNMPDLIARLTSMTQEQDGIDFSVVSIDFESGCDLINTAHTTKDLDVLIAPYGNGLGAGLFMKDDAVVIAIMSRYWNDGWFKFPMTAVGRRVFNFECTNEICKEYEPKLAQQVLDIYGVQLNTTEMNEFLTTSNPEPLLNERIPGRAWYPFLQYYKDVARRVDTDRFIPFLKDIMHNKPSANISYPDSCRKPNVCCDLDCNEALERNVFSETSAWK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NAN9</accession>
    <name>A0A1C7NAN9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Forkhead box protein I1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">foxi1</name>
        <name evidence="6" type="ORF">A0J61_07507</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000509">
        <property type="protein sequence ID" value="OBZ84444.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NAN9"/>
    <dbReference type="STRING" id="101091.A0A1C7NAN9"/>
    <dbReference type="InParanoid" id="A0A1C7NAN9"/>
    <dbReference type="OrthoDB" id="5954824at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00059">
        <property type="entry name" value="FH_FOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.10:FF:000135">
        <property type="entry name" value="forkhead box protein G1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001766">
        <property type="entry name" value="Fork_head_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050211">
        <property type="entry name" value="FOX_domain-containing"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018122">
        <property type="entry name" value="TF_fork_head_CS_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030456">
        <property type="entry name" value="TF_fork_head_CS_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11829:SF343">
        <property type="entry name" value="FORK-HEAD DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11829">
        <property type="entry name" value="FORKHEAD BOX PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00250">
        <property type="entry name" value="Forkhead"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00053">
        <property type="entry name" value="FORKHEAD"/>
    </dbReference>
    <dbReference type="SMART" id="SM00339">
        <property type="entry name" value="FH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00657">
        <property type="entry name" value="FORK_HEAD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00658">
        <property type="entry name" value="FORK_HEAD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50039">
        <property type="entry name" value="FORK_HEAD_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2 3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fork-head" evidence="5">
        <location>
            <begin position="56"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="Fork-head" evidence="3">
        <location>
            <begin position="56"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="171"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="235"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="191"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50039"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OBZ84444.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="441" mass="51046" checksum="A2A62DA021DA9F32" modified="2016-11-30" version="1" fragment="single">THNAKKQKPSELKFKIEPIGIQPEDDDDLETCPSRTRSSWPHQIVPWWKPADRYEKPPYSYATLIAHAILTSKDGRLTLSDIYKWISEVYPYYKRGQKGWQNSIRHNLSLNKKWFIKVDRRPTQAHPGKGGYWTLQVNMEKVFVDNLCQAGGHSRRHHDIGMYSSLSTQHYRASPDKQEPSPQGCPNIHITRPEDFETKKNTVRTRPQEKEEVPKTDPKNFIIRFNPLDLKRKTLKSSTKRDRSPEIQTISKKRKPTTTTTTVDTMAASPYMLSYPMSYNTDNRTKSSLDKDMLGFNDFWMYDEPDQEPSLLLTSSYPTMLLDVEAQNILHGLQSTPAQVINHHPDMKTIDLQSFSLEKNIHYPNAFAVEEFSDPNSSLFVSDLSSYNMDQYVDFGGSMMSDDLPSDVLLENDTLNTYWPETTPCYMFDVNSTTMPFVKYE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NB42</accession>
    <name>A0A1C7NB42_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Protein transport protein sec1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">sec1_0</name>
        <name evidence="3" type="ORF">A0J61_05650</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the STXBP/unc-18/SEC1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000311">
        <property type="protein sequence ID" value="OBZ86303.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NB42"/>
    <dbReference type="FunCoup" id="A0A1C7NB42">
        <property type="interactions" value="351"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NB42"/>
    <dbReference type="InParanoid" id="A0A1C7NB42"/>
    <dbReference type="OrthoDB" id="2228at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016192">
        <property type="term" value="P:vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1910">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2060">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.830.10">
        <property type="entry name" value="Syntaxin Binding Protein 1, Chain A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043154">
        <property type="entry name" value="Sec-1-like_dom1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043127">
        <property type="entry name" value="Sec-1-like_dom3a"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001619">
        <property type="entry name" value="Sec1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027482">
        <property type="entry name" value="Sec1-like_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036045">
        <property type="entry name" value="Sec1-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11679">
        <property type="entry name" value="VESICLE PROTEIN SORTING-ASSOCIATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00995">
        <property type="entry name" value="Sec1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005715">
        <property type="entry name" value="VPS45_Sec1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56815">
        <property type="entry name" value="Sec1/munc18-like (SM) proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="616"/>
            <end position="671"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="635"/>
            <end position="646"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="648"/>
            <end position="662"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ86303.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="671" mass="75448" checksum="FA91EE45392CB9A9" modified="2016-11-30" version="1">MIGIDDILKKRFLELIKTVNPTGRWKLVVVDSLSSKILNSACKMYDILEENVTLVENIEKPRQPYPSYEAIYILTPCIESCSRLVDDFSRPEGKMYAAAHVHFINALENNTFNEFTRLLTAANAANDIKSLKEMYVDFLDDERKFIRLFANTEPNSIHTQAEIEDIAKQLLCVCVTLGENPLIRYHRPLDIKETVNRRIPEQLAKAVQSELDNFCATNPEYPPPRDPPLPSGTLIILDRTIDPISPFLHEFTYQAMIADLLEVEEIPTGLKYEYKYTQEDGTTQDQEVTLVEADPVYCTIRHMHIANTTDKLINDFNAFVNENQIGGSSGPATAASLNDMKNIISNLPQYQEMKSRFSAHMNIASECMSEFKSQNLEEIGLLEQDMACGETPEGEKPTNLVEALVPILDDPLTSQMVKTRLILLWIATSDAIDPEDLEQLMAVARLEQEYKDAIDNIKFLGVQLSKTANKLGKKSKKGSKKKVNPQQEVPFDLSRYVPVVKRIVEGHIDGTIDQSLFPNNIRNVKQQNTRKNTEEAVKEVPKLRVYKTQWHKKSTKGANAPPKPPSGPPIIIFIVGGMTYSEIRSAYEIAETFDREVYIGSTHIITPDKFVTDLSKLDKKAPPPKGLIPPYTGSIHKSNPVSNHAQPSLPLRAASSLPSSSSKSHKLLGKW</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NBT7</accession>
    <name>A0A1C7NBT7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_05500</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000298">
        <property type="protein sequence ID" value="OBZ86448.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NBT7"/>
    <dbReference type="STRING" id="101091.A0A1C7NBT7"/>
    <dbReference type="InParanoid" id="A0A1C7NBT7"/>
    <dbReference type="OrthoDB" id="445556at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="248"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="275"/>
            <end position="300"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ86448.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="355" mass="40590" checksum="4B6A2BBCB88E29F5" modified="2016-11-30" version="1">MSLVQKIRIIPFAQPVRVAEKSFEDYHQKGFFSAHILQSSPPKQSFLPFWVVSATVDATIEQAQVGRRVMRTRYNAATKRNESAWETDWVWVPEQHSFSRRYLPLSHPGLQIYGSYKHRRGLVEKITTGSALESTVPFAPEIVNKDADGVVRKVDPFLIYPSTALRLAKSYLHQSEEKLADEFLRKVYRMDDTRFLKINMKVSNIRVSPVYYPVYTFSVHYLGKKLHTFVNGHDLSIGGTKVYDWEKVAAASTIGMAATMFTTGGIEWGGASGSFWLGVVLPTLATSVLALYLPLITLTFRDFKRNREIKSMAQDSETWDENYVQEFIAIKDQSGQRTWYEEESIDSDDSSYHNN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NBX6</accession>
    <name>A0A1C7NBX6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">RRM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">A0J61_07097</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000462">
        <property type="protein sequence ID" value="OBZ84854.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NBX6"/>
    <dbReference type="STRING" id="101091.A0A1C7NBX6"/>
    <dbReference type="InParanoid" id="A0A1C7NBX6"/>
    <dbReference type="OrthoDB" id="439808at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030686">
        <property type="term" value="C:90S preribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032040">
        <property type="term" value="C:small-subunit processome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030515">
        <property type="term" value="F:snoRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042274">
        <property type="term" value="P:ribosomal small subunit biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd12400">
        <property type="entry name" value="RRM_Nop6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.330:FF:000376">
        <property type="entry name" value="Putative RNA binding protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034228">
        <property type="entry name" value="Nop6_RRM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23236">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 4B/4H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23236:SF51">
        <property type="entry name" value="NUCLEOLAR PROTEIN 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="4">
        <location>
            <begin position="95"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="170"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="44"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="78"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="178"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="205"/>
            <end position="217"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OBZ84854.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="217" mass="24742" checksum="184C924F8DEDA56C" modified="2016-11-30" version="1">MAPEKKLTKKEQKALAFKKRAKKPQFTDDMAVPASDDTPAAEEVAEKTPKVEEEEKKKTNNKRKATSQAIEVPQEGSTGEKKNNKRSKKEDQNRYIIFVGNLPYTTTKEELEKHFESAGKIRSVRLLTAKATGKPKGFAFMEFENSKDLNKALAFHHTFFKKRQINVELTAGGGGNKSDARKEKLKTKNERLKEERTKKHEQLKQDNTQASSYKLDQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NBY4</accession>
    <name>A0A1C7NBY4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Putative formaldehyde dehydrogenase AdhA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">adhA_1</name>
        <name evidence="8" type="ORF">A0J61_05319</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 5">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the zinc-containing alcohol dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000284">
        <property type="protein sequence ID" value="OBZ86632.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NBY4"/>
    <dbReference type="FunCoup" id="A0A1C7NBY4">
        <property type="interactions" value="328"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NBY4"/>
    <dbReference type="InParanoid" id="A0A1C7NBY4"/>
    <dbReference type="OrthoDB" id="1879366at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016616">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05283">
        <property type="entry name" value="CAD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000022">
        <property type="entry name" value="Cinnamyl alcohol dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002328">
        <property type="entry name" value="ADH_Zn_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047109">
        <property type="entry name" value="CAD-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029752">
        <property type="entry name" value="D-isomer_DH_CS1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42683">
        <property type="entry name" value="ALDEHYDE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00059">
        <property type="entry name" value="ADH_ZINC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00065">
        <property type="entry name" value="D_2_HYDROXYACID_DH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Alcohol dehydrogenase-like N-terminal" evidence="7">
        <location>
            <begin position="31"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="domain" description="Alcohol dehydrogenase-like C-terminal" evidence="6">
        <location>
            <begin position="189"/>
            <end position="311"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU361277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00107"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF08240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OBZ86632.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="348" mass="38678" checksum="69ED18E72F579893" modified="2016-11-30" version="1">MSEETFTAYVCKSKGAALEPMEVNFCHWDEDMVQMDVICCGVCGTDIHTIDEGWGPTDFPCVVGHEIIGRVTKVGNNVTRIKVGDRCGVGCQSASCGHCDYCKKDMENLCSTHCVWTFNDHYDNDHKDKTYGGFAKKWRGNQNFVVKVPDDLESEVAASFLCGGVTTFAPLKRYNVGKGSKVAVLGMGGLGHFAVQWAKAMGAEVVAFDVIPDKVHDAKKLGCDEYVLMQKEEQMEPHYNTFTHILATKIVNKCWDQYFKMLKNNGIFILCDIPEVPLSGMSAFVMCGKQLTIAASFIGSPSVIQECLDFAGEHNIKTWVNTFPMENINEAIQFVRDGKPRYRAVVKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NC34</accession>
    <name>A0A1C7NC34_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Protein BIG1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">A0J61_05645</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the BIG1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000311">
        <property type="protein sequence ID" value="OBZ86299.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NC34"/>
    <dbReference type="STRING" id="101091.A0A1C7NC34"/>
    <dbReference type="InParanoid" id="A0A1C7NC34"/>
    <dbReference type="OrthoDB" id="10029326at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006078">
        <property type="term" value="P:(1-&gt;6)-beta-D-glucan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009272">
        <property type="term" value="P:fungal-type cell wall biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037654">
        <property type="entry name" value="Big1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046756">
        <property type="entry name" value="VAS1/VOA1_TM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28285">
        <property type="entry name" value="PROTEIN BIG1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28285:SF1">
        <property type="entry name" value="PROTEIN BIG1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20520">
        <property type="entry name" value="Ac45-VOA1_TM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="6" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 11" id="KW-0732">Signal</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="11">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008889603" description="Protein BIG1" evidence="11">
        <location>
            <begin position="20"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="232"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="domain" description="V-type proton ATPase subunit S1/VOA1 transmembrane" evidence="12">
        <location>
            <begin position="226"/>
            <end position="263"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF20520"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="OBZ86299.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="273" mass="29828" checksum="C4C5CF01E761A30F" modified="2016-11-30" version="1">MKLLATATTLFSLTSVVLAYEASSVPCLMWSPKNYIVDNAKSNSQIVLSSSDATSTILSSLSSDICSAKVITLVNQPEIQSTTLARHGYENAFSQLKEYNSEAATRTQIKYISNGVDVEQVAKQIASQCDAEVSTLDPSAVARENFVAKNAPVVAIVPLPSSNNDVNILEDNNKLLDQVLETVKEEVHDDYVVIYTSSSAKPSSSQTLRRRAPQAPQDLPIFKKYQLFTPGVFMVLGVVFLFMFIAGTGITWLVGIQTPLRFEGPANKQKKQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NCJ8</accession>
    <name>A0A1C7NCJ8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Aldehyde dehydrogenase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">Aldh3a1</name>
        <name evidence="8" type="ORF">A0J61_05113</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the aldehyde dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000267">
        <property type="protein sequence ID" value="OBZ86842.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NCJ8"/>
    <dbReference type="STRING" id="101091.A0A1C7NCJ8"/>
    <dbReference type="InParanoid" id="A0A1C7NCJ8"/>
    <dbReference type="OrthoDB" id="440325at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004029">
        <property type="term" value="F:aldehyde dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006081">
        <property type="term" value="P:aldehyde metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07087">
        <property type="entry name" value="ALDH_F3-13-14_CALDH-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.309.10:FF:000025">
        <property type="entry name" value="Aldehyde dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.605.10:FF:000004">
        <property type="entry name" value="Aldehyde dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.605.10">
        <property type="entry name" value="Aldehyde Dehydrogenase, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.309.10">
        <property type="entry name" value="Aldehyde Dehydrogenase, Chain A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016161">
        <property type="entry name" value="Ald_DH/histidinol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016163">
        <property type="entry name" value="Ald_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016160">
        <property type="entry name" value="Ald_DH_CS_CYS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016162">
        <property type="entry name" value="Ald_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015590">
        <property type="entry name" value="Aldehyde_DH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012394">
        <property type="entry name" value="Aldehyde_DH_NAD(P)"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43570">
        <property type="entry name" value="ALDEHYDE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43570:SF16">
        <property type="entry name" value="ALDEHYDE DEHYDROGENASE TYPE III, ISOFORM Q"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00171">
        <property type="entry name" value="Aldedh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036492">
        <property type="entry name" value="ALDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53720">
        <property type="entry name" value="ALDH-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00070">
        <property type="entry name" value="ALDEHYDE_DEHYDR_CYS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0520">NAD</keyword>
    <keyword evidence="2 4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="483"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="domain" description="Aldehyde dehydrogenase" evidence="7">
        <location>
            <begin position="13"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="active site" evidence="5">
        <location>
            <position position="218"/>
        </location>
    </feature>
    <feature type="active site" evidence="5">
        <location>
            <position position="252"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009986"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRNR" id="PIRNR036492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR036492-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OBZ86842.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="504" mass="56639" checksum="D6078FCE57F4E417" modified="2016-11-30" version="1">MSKQVEYTALDRIEDHVSSLRQVFLSGKLRDLKKRKQQLHQLYRLVEENQEAIHEALAQDLRKPKHEAFSGEIAPVLDECLYFIEHLDRLAKDEKVKPRLTINRLAQVMIRREPLGLVLILGCWNYPLALVPLAGAIAAGNTVILKPSEIAPYTATLISRLFSLYMDTNCYRIVNGGPEETTELLKYPFDHIFYTGNQQVAKIIMTAAAQHLTPVTLELGGKCPAIILSDADIQLTANRIAWGKLFNAGQVCIAVDYVVCPTSKRDAFVAAYKRVLEEWYTDPQTSKDYARIVSERHVKRIADMLNQRQSGEIVVGGTIDLEDRYVAPTLVTGVDFDDPSLMSDEIFGPVLPLITYQALDEAIAMVNRHPSPLALYLFSNQKSSIEQVLNNTRSGGVTINDCLVHQAEYAIPFGGVGASGMGSYHGDKSFSTFTHERSMIIKKQTMEGSNQARYPPYSESKYALLRLVLGHHPLMLTLKKYKSPLKIIVAICAFLVFYFKRKNM</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NCT6</accession>
    <name>A0A1C7NCT6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_05051</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000262">
        <property type="protein sequence ID" value="OBZ86901.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NCT6"/>
    <dbReference type="STRING" id="101091.A0A1C7NCT6"/>
    <dbReference type="InParanoid" id="A0A1C7NCT6"/>
    <dbReference type="OrthoDB" id="2250996at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008889626" evidence="1">
        <location>
            <begin position="19"/>
            <end position="278"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ86901.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="278" mass="32808" checksum="C43AB70865AA3584" modified="2016-11-30" version="1">MLVYYFVLLYCFCCGCHAVAVTHVKAPQTAFYLQQTQPFEVNSDFSSEEYILYTEVVQHYENLVDTTLNSQSEELFLYLIYMPTESKCQLLKAQVQFLGIDQPMSRSQLLKIPTIISKHVQSMNTHIYESIDPIIQRHWKTLWENRLLEPSRAEAELSRLLSSLNSILAIQLVEQMDAYQLVERVQQDIRMMIQGAEVESMSHKWLSWLSHPLLVVSRSYQAQNKPRVHQEVDFLRQHLTDLRVQLLMELHLQFVDLFSRMKVDVIEQLNEYYNELEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7ND67</accession>
    <name>A0A1C7ND67_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="18">Protein transport protein SEC24</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="18" type="primary">SEC24_0</name>
        <name evidence="18" type="ORF">A0J61_04872</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18 19">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="3">Endoplasmic reticulum membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Golgi apparatus membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the SEC23/SEC24 family. SEC24 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000249">
        <property type="protein sequence ID" value="OBZ87072.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7ND67"/>
    <dbReference type="FunCoup" id="A0A1C7ND67">
        <property type="interactions" value="441"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7ND67"/>
    <dbReference type="InParanoid" id="A0A1C7ND67"/>
    <dbReference type="OrthoDB" id="49016at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030127">
        <property type="term" value="C:COPII vesicle coat"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070971">
        <property type="term" value="C:endoplasmic reticulum exit site"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000149">
        <property type="term" value="F:SNARE binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090110">
        <property type="term" value="P:COPII-coated vesicle cargo loading"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1670">
        <property type="entry name" value="beta-sandwich domain of Sec23/24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.730">
        <property type="entry name" value="Sec23/Sec24 helical domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.20.10">
        <property type="entry name" value="Severin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.410">
        <property type="entry name" value="von Willebrand factor, type A domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.380">
        <property type="entry name" value="Zn-finger domain of Sec23/24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029006">
        <property type="entry name" value="ADF-H/Gelsolin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012990">
        <property type="entry name" value="Beta-sandwich_Sec23_24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007123">
        <property type="entry name" value="Gelsolin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036180">
        <property type="entry name" value="Gelsolin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006900">
        <property type="entry name" value="Sec23/24_helical_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036175">
        <property type="entry name" value="Sec23/24_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006896">
        <property type="entry name" value="Sec23/24_trunk_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050550">
        <property type="entry name" value="SEC23_SEC24_subfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036465">
        <property type="entry name" value="vWFA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006895">
        <property type="entry name" value="Znf_Sec23_Sec24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036174">
        <property type="entry name" value="Znf_Sec23_Sec24_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13803">
        <property type="entry name" value="SEC24-RELATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13803:SF39">
        <property type="entry name" value="SECRETORY 24AB, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00626">
        <property type="entry name" value="Gelsolin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08033">
        <property type="entry name" value="Sec23_BS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04815">
        <property type="entry name" value="Sec23_helical"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04811">
        <property type="entry name" value="Sec23_trunk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04810">
        <property type="entry name" value="zf-Sec23_Sec24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81995">
        <property type="entry name" value="beta-sandwich domain of Sec23/24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82754">
        <property type="entry name" value="C-terminal, gelsolin-like domain of Sec23/24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81811">
        <property type="entry name" value="Helical domain of Sec23/24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53300">
        <property type="entry name" value="vWA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82919">
        <property type="entry name" value="Zn-finger domain of Sec23/24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="8" id="KW-0931">ER-Golgi transport</keyword>
    <keyword evidence="10" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="11" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0653">Protein transport</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Zinc finger Sec23/Sec24-type" evidence="14">
        <location>
            <begin position="130"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="domain" description="Sec23/Sec24 trunk" evidence="15">
        <location>
            <begin position="204"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="domain" description="Sec23/Sec24 beta-sandwich" evidence="17">
        <location>
            <begin position="453"/>
            <end position="536"/>
        </location>
    </feature>
    <feature type="domain" description="Sec23/Sec24 helical" evidence="16">
        <location>
            <begin position="547"/>
            <end position="636"/>
        </location>
    </feature>
    <feature type="domain" description="Gelsolin-like" evidence="13">
        <location>
            <begin position="676"/>
            <end position="750"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="12">
        <location>
            <begin position="430"/>
            <end position="457"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004394"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004586"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00008334"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF00626"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF04810"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF04811"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF04815"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF08033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="OBZ87072.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="822" mass="92738" checksum="62C369135EE2B997" modified="2016-11-30" version="1">MTPQRNQRAHHQESCFVQPSLSITESPSKVSLYAQDNKISRRLDVALLGSAPMIDDLHSPCVTPEIPATAAITVSDQSQCHPGFQRCTLSAIPSSHHLLKRSKLPLSVLIEPYPRQLPVHVPYIEDGLINRCRDCRSFINPFSKFIEGGLKWQCNLCGLDDNDVPPAYDWNHLTQQKVNRWDRAELNYGCVDYMATSEFMSRPPQPPTYIVVIDTSAIAVQTGLIEVLSEALVSTLDEIPNKDGRTRIGFVTASDAIGFYSFANKEPELLMVSDMDDIFLPRSSSDLVVNLNESRSIVLDLLNRLQVMFKKSVSIDNRNCLGSALLAARQLLSSTGGKIICLQAISPNYGNGALLPSRVHRQNVNTTSDSTLLNPANEFYKAFSEECVRSHVCVDMFVFGSQDIDVATLSTYNVLPKYTGGQTHYYPGFNAKNQCDREKFRQEIEKLVKEQMGLEAIVRTRCSPGLVCSAYYGNFSFQEPDILVLPNVSRDGSFCMDLMIDRDIQEEFVSIQTCMLLTTSEGERIIRVMTTCLPVTKYVTELFYSADQSSIARSLAYQALERASTRKIKDGKDYLTRRTVDICRSYSKEVIGVLPSKSMQLNVCRSLNLLPAMILAILKTEAFNFTGGVPANMSNQSGILLWTLPHRLWLRYIYPSFYSLHNMPIQAGTLDTDSQVVMPPCLNLSSERLDRHGCYLLENGQRIFLWIGREAVPQLCIDLLGLSSINQVMSGQLTSLPVLNNPFSERVRRIVESVRTDQRHSNFYPSLYIIKEDGDPLLCHLFMMHLIENRRQLTDGYGLSKKTIDFSSISYFEWLHFIKEQM</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NDH0</accession>
    <name>A0A1C7NDH0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="23">Folic acid synthesis protein FOL1</fullName>
            <ecNumber evidence="10">2.5.1.15</ecNumber>
            <ecNumber evidence="12">2.7.6.3</ecNumber>
            <ecNumber evidence="11">4.1.2.25</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="24">Folic acid synthesis protein fol1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="26" type="primary">fol1</name>
        <name evidence="26" type="ORF">A0J61_04837</name>
    </gene>
    <organism evidence="26 27">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="26 27" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="26 27">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="21">Catalyzes three sequential steps of tetrahydrofolate biosynthesis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>(7,8-dihydropterin-6-yl)methyl diphosphate + 4-aminobenzoate = 7,8-dihydropteroate + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:19949"/>
            <dbReference type="ChEBI" id="CHEBI:17836"/>
            <dbReference type="ChEBI" id="CHEBI:17839"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:72950"/>
            <dbReference type="EC" id="2.5.1.15"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>6-hydroxymethyl-7,8-dihydropterin + ATP = (7,8-dihydropterin-6-yl)methyl diphosphate + AMP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:11412"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:44841"/>
            <dbReference type="ChEBI" id="CHEBI:72950"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="2.7.6.3"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3 28">
            <text>7,8-dihydroneopterin = 6-hydroxymethyl-7,8-dihydropterin + glycolaldehyde</text>
            <dbReference type="Rhea" id="RHEA:10540"/>
            <dbReference type="ChEBI" id="CHEBI:17001"/>
            <dbReference type="ChEBI" id="CHEBI:17071"/>
            <dbReference type="ChEBI" id="CHEBI:44841"/>
            <dbReference type="EC" id="4.1.2.25"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="6">Cofactor biosynthesis; tetrahydrofolate biosynthesis; 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate from 7,8-dihydroneopterin triphosphate: step 3/4.</text>
    </comment>
    <comment type="pathway">
        <text evidence="7">Cofactor biosynthesis; tetrahydrofolate biosynthesis; 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate from 7,8-dihydroneopterin triphosphate: step 4/4.</text>
    </comment>
    <comment type="pathway">
        <text evidence="5">Cofactor biosynthesis; tetrahydrofolate biosynthesis; 7,8-dihydrofolate from 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate and 4-aminobenzoate: step 1/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="9">In the C-terminal section; belongs to the DHPS family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="8">In the N-terminal section; belongs to the DHNA family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="22">In the central section; belongs to the HPPK family.</text>
    </comment>
    <comment type="caution">
        <text evidence="26">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.15" evidence="10"/>
    <dbReference type="EC" id="2.7.6.3" evidence="12"/>
    <dbReference type="EC" id="4.1.2.25" evidence="11"/>
    <dbReference type="EMBL" id="LUGH01000246">
        <property type="protein sequence ID" value="OBZ87108.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NDH0"/>
    <dbReference type="FunCoup" id="A0A1C7NDH0">
        <property type="interactions" value="220"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NDH0"/>
    <dbReference type="InParanoid" id="A0A1C7NDH0"/>
    <dbReference type="OrthoDB" id="615426at2759"/>
    <dbReference type="UniPathway" id="UPA00077">
        <property type="reaction ID" value="UER00155"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005740">
        <property type="term" value="C:mitochondrial envelope"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003848">
        <property type="term" value="F:2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004150">
        <property type="term" value="F:dihydroneopterin aldolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004156">
        <property type="term" value="F:dihydropteroate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046656">
        <property type="term" value="P:folic acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046654">
        <property type="term" value="P:tetrahydrofolate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd00739">
        <property type="entry name" value="DHPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00483">
        <property type="entry name" value="HPPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.20:FF:000006">
        <property type="entry name" value="Dihydropteroate synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1130.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.560">
        <property type="entry name" value="7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase HPPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.20">
        <property type="entry name" value="Dihydropteroate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045031">
        <property type="entry name" value="DHP_synth-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006390">
        <property type="entry name" value="DHP_synth_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011005">
        <property type="entry name" value="Dihydropteroate_synth-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006157">
        <property type="entry name" value="FolB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043133">
        <property type="entry name" value="GTP-CH-I_C/QueF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000550">
        <property type="entry name" value="Hppk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035907">
        <property type="entry name" value="Hppk_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000489">
        <property type="entry name" value="Pterin-binding_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01496">
        <property type="entry name" value="DHPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00526">
        <property type="entry name" value="folB_dom"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01498">
        <property type="entry name" value="folK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20941">
        <property type="entry name" value="FOLATE SYNTHESIS PROTEINS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20941:SF1">
        <property type="entry name" value="FOLIC ACID SYNTHESIS PROTEIN FOL1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02152">
        <property type="entry name" value="FolB"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01288">
        <property type="entry name" value="HPPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00809">
        <property type="entry name" value="Pterin_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00905">
        <property type="entry name" value="FolB"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55083">
        <property type="entry name" value="6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase, HPPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51717">
        <property type="entry name" value="Dihydropteroate synthetase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55620">
        <property type="entry name" value="Tetrahydrobiopterin biosynthesis enzymes-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00792">
        <property type="entry name" value="DHPS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00793">
        <property type="entry name" value="DHPS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00794">
        <property type="entry name" value="HPPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50972">
        <property type="entry name" value="PTERIN_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="17" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="19" id="KW-0289">Folate biosynthesis</keyword>
    <keyword evidence="16" id="KW-0418">Kinase</keyword>
    <keyword evidence="18" id="KW-0460">Magnesium</keyword>
    <keyword evidence="14" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="20" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="15" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="27" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="13" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Pterin-binding" evidence="25">
        <location>
            <begin position="481"/>
            <end position="747"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00000198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001353"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00004763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00005013"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00005051"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00009640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00009951"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00012458"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00013043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00013253"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00022909"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="21">
        <source>
            <dbReference type="ARBA" id="ARBA00058009"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="22">
        <source>
            <dbReference type="ARBA" id="ARBA00061548"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="23">
        <source>
            <dbReference type="ARBA" id="ARBA00067568"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="24">
        <source>
            <dbReference type="ARBA" id="ARBA00068111"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="25">
        <source>
            <dbReference type="PROSITE" id="PS50972"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="26">
        <source>
            <dbReference type="EMBL" id="OBZ87108.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="27">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="758" mass="84201" checksum="B6C5B7039A9F3603" modified="2016-11-30" version="1">MEDKQYDKILIKNLVLKNVAGVEAWQRLKSQPVVITVELFTDITAAGNTDHVTNTIHYGHVTKAITKLGETSTFPTLEALAHAVVKLCCVQFGAARTQVVVEQPKALLHAAASGVKLARAIEDYKDLASDVIETTGQVSGLGVRDEIFVRDLRLHTIVGVNPWEREEKQVVIINLKVYPSSIPYGDHLLADAERNKSHNLRTIVRTLTRHIEASGYKTIEAFGVTVARLALEKCHVNKVSVRVEKPSAILFADCSGLEVTRDRIWLEQVIEQEKAAGQKFIHHDGMLHYTKDVPSNYNQIAYIAFGSNVGDRVNNINQALQLLESECESIVLDTSFLYETPPMYYTEQPTFLNGVCKIATHLDPHALLKKLKEAENTLGRLPSFRNGPRPIDLDILFYNDLVLEDGDLLTIPHKSIQEREFVLWPLNDIARDMEHPRLFKTNGQLLSQLLKVTAESKEGPLKIDKVAPIQKQTLWRWNDKTYVMGILNTTPDSFSDGGKHSNVEQAVAAAWKMKEEGADIIDIGGMSTRPGADDTFPEEEEIRRVVPVIEQLRASGFDLPISVDTFRASVAKAAIEAGADLINDISGGSRDPNMLKVMAECKVPVCLMHMRGDAQTMMSKENTTYENDDVVDDVTHVLHVLVERAIAAGVHRWNIIIDPGVGFAKTAEQDFELLRHLGEMSEGQDSLLRGFPSLVGISRKKFIGGVTGVKEAEKRAFGTAGAVAACVAGNANILRVHDVRPMWEVIQVCDQVWKKTRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NE85</accession>
    <name>A0A1C7NE85_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Zinc homeostasis factor 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">zhf1</name>
        <name evidence="11" type="ORF">A0J61_04549</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000225">
        <property type="protein sequence ID" value="OBZ87401.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NE85"/>
    <dbReference type="FunCoup" id="A0A1C7NE85">
        <property type="interactions" value="139"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NE85"/>
    <dbReference type="InParanoid" id="A0A1C7NE85"/>
    <dbReference type="OrthoDB" id="9944568at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005385">
        <property type="term" value="F:zinc ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006882">
        <property type="term" value="P:intracellular zinc ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1510.10">
        <property type="entry name" value="Cation efflux protein transmembrane domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002524">
        <property type="entry name" value="Cation_efflux"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027470">
        <property type="entry name" value="Cation_efflux_CTD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036837">
        <property type="entry name" value="Cation_efflux_CTD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058533">
        <property type="entry name" value="Cation_efflux_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027469">
        <property type="entry name" value="Cation_efflux_TMD_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01297">
        <property type="entry name" value="CDF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45820">
        <property type="entry name" value="FI23527P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45820:SF4">
        <property type="entry name" value="ZINC TRANSPORTER 63C, ISOFORM F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01545">
        <property type="entry name" value="Cation_efflux"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16916">
        <property type="entry name" value="ZT_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160240">
        <property type="entry name" value="Cation efflux protein cytoplasmic domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161111">
        <property type="entry name" value="Cation efflux protein transmembrane domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="52"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="83"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="142"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="172"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="domain" description="Cation efflux protein transmembrane" evidence="9">
        <location>
            <begin position="11"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="domain" description="Cation efflux protein cytoplasmic" evidence="10">
        <location>
            <begin position="211"/>
            <end position="278"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008873"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01545"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF16916"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="OBZ87401.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="345" mass="38793" checksum="B43A828D3FA44937" modified="2016-11-30" version="1">MQCHLNKAIQIADSFHMLSDMISMCVALWAIKVSQKTKHDPHYSYGWQRAEILGALVNGVFLLALCFTILIDCIKRFVEPESVNHPMLVLVIGSAGLVANLIGLLIFHEHGHIGHHHSHADDKEAQGDHDHSHNGHLNMRGIFLHVLGDALGNVGVIASSLFIWLTDFSWRFYFDPIVSCLLTIIIFMSAIPLVRQTSFILLQGVPHSVPLDDVNSTLLTLENVLSVHELHVWQLSDTKLIATLHVLIRSRKDYMTTATEIRKILHRYGIHSVTLQPEFIEDQIDEKYIDDCKNQTEKDSDSSTSIKVIHNQASKETLTEGSSTCFLRCLDESCLESSCCPPEDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NFD3</accession>
    <name>A0A1C7NFD3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Pre-mRNA-splicing factor sap61</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">sap61</name>
        <name evidence="10" type="ORF">A0J61_04177</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SF3A3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000198">
        <property type="protein sequence ID" value="OBZ87768.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NFD3"/>
    <dbReference type="FunCoup" id="A0A1C7NFD3">
        <property type="interactions" value="1291"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NFD3"/>
    <dbReference type="InParanoid" id="A0A1C7NFD3"/>
    <dbReference type="OrthoDB" id="2160351at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005681">
        <property type="term" value="C:spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000690">
        <property type="entry name" value="Matrin/U1-C_Znf_C2H2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003604">
        <property type="entry name" value="Matrin/U1-like-C_Znf_C2H2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051421">
        <property type="entry name" value="RNA_Proc_DNA_Dmg_Regulator"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031774">
        <property type="entry name" value="SF3A3_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024598">
        <property type="entry name" value="SF3a60/Prp9_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021966">
        <property type="entry name" value="SF3a60_bindingd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12786:SF2">
        <property type="entry name" value="SPLICING FACTOR 3A SUBUNIT 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12786">
        <property type="entry name" value="SPLICING FACTOR SF3A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16837">
        <property type="entry name" value="SF3A3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12108">
        <property type="entry name" value="SF3a60_bindingd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11931">
        <property type="entry name" value="SF3a60_Prp9_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12874">
        <property type="entry name" value="zf-met"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00451">
        <property type="entry name" value="ZnF_U1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50171">
        <property type="entry name" value="ZF_MATRIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <keyword evidence="5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Matrin-type" evidence="9">
        <location>
            <begin position="367"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="302"/>
            <end position="336"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OBZ87768.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="462" mass="54879" checksum="56C5A92DFB84F954" modified="2016-11-30" version="1">MDNILEKQRSAHEAIERLEQAIVDQYMQDAKVHRERLQNEHVIDTFLTRISEKSAYLAELYQDKDGLRQSEMEALSTSEFSEFYERLKVVKEHHRKYPNEPVDPPELEFIYLSQRTEEEELENMFSGEESTGRYLDLIGLHTAYINLKGVKKLDYLQYLAEFDAFDTNYPKTIKTTEEYKQYLDQLKDYLHGFFRRAKPLFDLKSLEEEASEQFEADWQQGKVKGWTTQQNSLFCSACQKQFTKQTVYDAHLTAKKHIKAQKKLEEEQNTKEDRRKVIAWHERLVMAYAEALNDFREETKANVERKQALTDKERTLEQEQEQVELIDQESEDEDDEKIYNPLKLPLGWDGKPIPYWLYKLHGLGVEYPCEICGNYVYMGRKAFDKHFQEWRHAHGMRCLGIPNTRQFHEITKIDDAYALYEKQKREGIAEEMKADTVEEFEDAEGNVYNKKTYEDLKRQGIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-06-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NFJ0</accession>
    <name>A0A1C7NFJ0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_04103</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000193">
        <property type="protein sequence ID" value="OBZ87847.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NFJ0"/>
    <dbReference type="InParanoid" id="A0A1C7NFJ0"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ87847.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="62" mass="6967" checksum="F858DF253D172F6A" modified="2016-11-30" version="1">MRVKQVNLLASEEDVTRIIKTIVAENFAVTHLNNQGRTSFFANKFPEVTITDATHGINNTSY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NG03</accession>
    <name>A0A1C7NG03_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">40S ribosomal protein S15</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">RPS15_3</name>
        <name evidence="5" type="ORF">A0J61_04469</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the universal ribosomal protein uS19 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000219">
        <property type="protein sequence ID" value="OBZ87486.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NG03"/>
    <dbReference type="STRING" id="101091.A0A1C7NG03"/>
    <dbReference type="InParanoid" id="A0A1C7NG03"/>
    <dbReference type="OrthoDB" id="10258210at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022627">
        <property type="term" value="C:cytosolic small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000028">
        <property type="term" value="P:ribosomal small subunit assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.860.10:FF:000002">
        <property type="entry name" value="40S ribosomal protein S15"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.860.10">
        <property type="entry name" value="30s Ribosomal Protein S19, Chain A"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00531">
        <property type="entry name" value="Ribosomal_uS19"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002222">
        <property type="entry name" value="Ribosomal_uS19"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005713">
        <property type="entry name" value="Ribosomal_uS19_euk/arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023575">
        <property type="entry name" value="Ribosomal_uS19_SF"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003121">
        <property type="entry name" value="PRK04038.1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01025">
        <property type="entry name" value="uS19_arch"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11880">
        <property type="entry name" value="RIBOSOMAL PROTEIN S19P FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11880:SF2">
        <property type="entry name" value="SMALL RIBOSOMAL SUBUNIT PROTEIN US19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00203">
        <property type="entry name" value="Ribosomal_S19"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00975">
        <property type="entry name" value="RIBOSOMALS19"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54570">
        <property type="entry name" value="Ribosomal protein S19"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 5" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OBZ87486.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="328" mass="37605" checksum="B34DAE2D79913F4F" modified="2016-11-30" version="1">MADEQTPRKRTFRKFTYRGIDLEQLLDLSSEQFMDLVHCRARRRFQRGLKRKPMGLIKKLRAAKKNAPSGEKPEVVKTHLRNMIIVPEMIGSVIGIYNGKTFNQVEIKPEMTGHYLGEFSITYKPVKHGRPGIGATHSSKLRITILYNTLYRKQATLHLTQTGQNYMHSSFSVGAWCQHSDALSADEQTPRKRTFRKFTYRGIDLEQLLDLSSEQFMDLVHCRARRRFQRGLKRKPMGLIKKLRAAKKNAPSGEKPEVVKTHLRNMIIVPEMIGSVIGIYNGKTFNQVEIKPEMTGHYLGEFSITYKPVKHGRPGIGATHSSKFVPLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NG06</accession>
    <name>A0A1C7NG06_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Meiotic activator RIM4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">RIM4</name>
        <name evidence="4" type="ORF">A0J61_04051</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000190">
        <property type="protein sequence ID" value="OBZ87900.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NG06"/>
    <dbReference type="STRING" id="101091.A0A1C7NG06"/>
    <dbReference type="InParanoid" id="A0A1C7NG06"/>
    <dbReference type="OrthoDB" id="410044at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00590">
        <property type="entry name" value="RRM_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003954">
        <property type="entry name" value="RRM_euk-type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10352">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00361">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="3">
        <location>
            <begin position="9"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="3">
        <location>
            <begin position="172"/>
            <end position="252"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OBZ87900.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="360" mass="41918" checksum="A042187C413AD297" modified="2016-11-30" version="1">MKKKEDPAACVFVASLSKDVPDEELQSDVFQHFLQWGTLSSVKVLKDWLKRPYAFVQFERVEDSKTAIKEAPGTILHGRSIRCEPARFIRSTLSSFGEIEDITVLQPHGKFHSIVVKFRYREDAIKAYLTLRFSDFEQISRHQQRWFVEWASNMDTDNLYGICGNACRLDKSSVFVGNLPQDTQQEELYGLFGSYGKVLNVHLIQKPYNRCSEKKVFAFIKYQHPFEAAQAIDQENGNVFKDKTLRVSYRQQYQRNPCQMTNRIPPLSIAVPPPSPDYFQHKFIEEYGPPQYMPNDTTVPINYAENVNQPNDAAGYTNPFYSTKEYNENACYMEPYPTIVYYAYPPYYPFKQVGYYTKQD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NGC6</accession>
    <name>A0A1C7NGC6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Phytanoyl-CoA dioxygenase domain-containing protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">PHYHD1</name>
        <name evidence="5" type="ORF">A0J61_03916</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the PhyH family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000180">
        <property type="protein sequence ID" value="OBZ88030.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NGC6"/>
    <dbReference type="STRING" id="101091.A0A1C7NGC6"/>
    <dbReference type="InParanoid" id="A0A1C7NGC6"/>
    <dbReference type="OrthoDB" id="445007at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051213">
        <property type="term" value="F:dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.620">
        <property type="entry name" value="q2cbj1_9rhob like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008775">
        <property type="entry name" value="Phytyl_CoA_dOase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20883">
        <property type="entry name" value="PHYTANOYL-COA DIOXYGENASE DOMAIN CONTAINING 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20883:SF15">
        <property type="entry name" value="PHYTANOYL-COA DIOXYGENASE DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05721">
        <property type="entry name" value="PhyH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="4" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005830"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OBZ88030.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="285" mass="32209" checksum="4E74C55E552DD744" modified="2016-11-30" version="1">MTVLTKEQIDQFNRDGCLVIPGFFSKEKAEALKSRAKQLLTDFSLENHPMTTFSTGTNDKQHVGDTYFLESGNKIRFFFEEDAFDEKGQLKVPKERAINKIGHGLHMLDPLFKDFSNNPTISTMTRELGFKAPQILQSMLIFKQPYIGGKVPPHQDSAFLYTEPLSAIGFWFALEDCTESNGCLWFIPGSHKTSPVTKRFVRNPHGSGTLFEGEDQFEVDETKYVKAEVDAGALVLIHGSVLHKSGHNLSPHSRYIYTFHCIEGEAHYPDNNWLQPMDGEPFTAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NGY3</accession>
    <name>A0A1C7NGY3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="3">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="primary">GIN4_0</name>
        <name evidence="15" type="ORF">A0J61_03711</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Bud neck</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. NIM1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="3"/>
    <dbReference type="EMBL" id="LUGH01000165">
        <property type="protein sequence ID" value="OBZ88240.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NGY3"/>
    <dbReference type="FunCoup" id="A0A1C7NGY3">
        <property type="interactions" value="383"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NGY3"/>
    <dbReference type="InParanoid" id="A0A1C7NGY3"/>
    <dbReference type="OrthoDB" id="504170at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005935">
        <property type="term" value="C:cellular bud neck"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005940">
        <property type="term" value="C:septin ring"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035556">
        <property type="term" value="P:intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd14081">
        <property type="entry name" value="STKc_BRSK1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000003">
        <property type="entry name" value="Non-specific serine/threonine protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000394">
        <property type="entry name" value="Serine/threonine-protein kinase HSL1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24346:SF82">
        <property type="entry name" value="KP78A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24346">
        <property type="entry name" value="MAP/MICROTUBULE AFFINITY-REGULATING KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 12" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8 15" id="KW-0418">Kinase</keyword>
    <keyword evidence="7 12" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="14">
        <location>
            <begin position="53"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="386"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="413"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="521"/>
            <end position="615"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="660"/>
            <end position="709"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="13"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="423"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="523"/>
            <end position="534"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="538"/>
            <end position="550"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="573"/>
            <end position="595"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="671"/>
            <end position="709"/>
        </location>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="82"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010791"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="OBZ88240.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="726" mass="81638" checksum="AD51CE2940F88517" modified="2016-11-30" version="1">MPEQSQTYRPNSRRPSASAASTRSSKSMRDRRRSSGAVSTHSQHKPKKYIGDYIVGKTLGKGASGRVKLGVHKHTGEQVAIKIISKTHLAANPAIEKAVRREIAIMKLIHHPNVMSLIDVIDDDSSPDLYLILEYVQGGELFEYLVSKGRLSESEARHHFQQIILGLDYCHHHLICHRDLKPENLLLNSKNNIKIADFGMASLQPIGSLLETSCGSPHYASPEIVAGMPYQGSACDIWSCGVILYALLTGHLPFDDENIRQLLKKVRSGRYVMPDNISRSAQDLIQRILVVDPSKRLNMQQIMLHPWFREVEPFNLHTLPIPPTKREIGQPVAVVSEIDNRLLETIKFLWGEAEDQTVVDALMQKEHNMQKVVYVLLQRHANRHWQAEHNDESDDDGNCTDNPQRQYHTLGRKSVRSKKHLSTAGSPVSKTVSSTMPSSRRPVNPWMPEAKPALSKRQSTATLRSEKALIDLPCSSPPLPSLALKPDKMKKSETFYAKFVKTVLSPSRKQYYPPQELVYRPNRHAEETPSREEPQMSPIPNSKPTSSTWVGTLRRKNPFQKSNAGTNKFDITIDSSNNQNSKSGTHRMSNANILQRNKIDPTSIEEPTNPRKSATLNAKKFSLRIANTFKTDEDTKKFGFTFNNTKKQRKQLDLSIFQSKHDSSLQPPPALLSDKSTLNSSSSISSSTQSSYSQSPQKSSTKTSSNMSSNLKPQKFITFLKSFTLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NH27</accession>
    <name>A0A1C7NH27_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Velvet domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">A0J61_03648</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000161">
        <property type="protein sequence ID" value="OBZ88308.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NH27"/>
    <dbReference type="STRING" id="101091.A0A1C7NH27"/>
    <dbReference type="InParanoid" id="A0A1C7NH27"/>
    <dbReference type="OrthoDB" id="5599552at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.3960">
        <property type="entry name" value="Velvet domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021740">
        <property type="entry name" value="Velvet"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037525">
        <property type="entry name" value="Velvet_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038491">
        <property type="entry name" value="Velvet_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33572">
        <property type="entry name" value="SPORE DEVELOPMENT REGULATOR VOSA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33572:SF3">
        <property type="entry name" value="VELVET COMPLEX SUBUNIT B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11754">
        <property type="entry name" value="Velvet"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51821">
        <property type="entry name" value="VELVET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Velvet" evidence="5">
        <location>
            <begin position="61"/>
            <end position="232"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51821"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OBZ88308.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="237" mass="27475" checksum="701F6FA44233726D" modified="2016-11-30" version="1">MEHEEDVFQTFIDYNEEEETKPKKNTVQLTFLEPNIDLETPQARKSSRYLFDKTLMNALSATTIDEAHLHLEIMEQPEQCRISNYGDKDRRPIDPAPIVRLRLEDEIKDLQPFYVIQVSLWSTDHKRQLDLVETRNQYMRALIGSVVASPSLLKGLGTNKEDYYFAFPDLSVRISGEYCLQFNLIHLARNKVIKSIYSNPFVVYTAKSYPGMKESSPLAKHLAKQGLKLTLRMHPPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NHA2</accession>
    <name>A0A1C7NHA2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Pumilio domain-containing protein P35G2.14</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">A0J61_03447</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000148">
        <property type="protein sequence ID" value="OBZ88501.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NHA2"/>
    <dbReference type="FunCoup" id="A0A1C7NHA2">
        <property type="interactions" value="12"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NHA2"/>
    <dbReference type="InParanoid" id="A0A1C7NHA2"/>
    <dbReference type="OrthoDB" id="2017782at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000288">
        <property type="term" value="P:nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00590">
        <property type="entry name" value="RRM_SF"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033133">
        <property type="entry name" value="PUM-HD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052645">
        <property type="entry name" value="Pumilio_domain_protein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001313">
        <property type="entry name" value="Pumilio_RNA-bd_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47093">
        <property type="entry name" value="PROTEIN JSN1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47093:SF1">
        <property type="entry name" value="PROTEIN JSN1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00806">
        <property type="entry name" value="PUF"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00025">
        <property type="entry name" value="Pumilio"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50302">
        <property type="entry name" value="PUM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50303">
        <property type="entry name" value="PUM_HD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="5">
        <location>
            <begin position="190"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="5">
        <location>
            <begin position="286"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="domain" description="PUM-HD" evidence="6">
        <location>
            <begin position="412"/>
            <end position="656"/>
        </location>
    </feature>
    <feature type="repeat" description="Pumilio" evidence="3">
        <location>
            <begin position="477"/>
            <end position="515"/>
        </location>
    </feature>
    <feature type="repeat" description="Pumilio" evidence="3">
        <location>
            <begin position="552"/>
            <end position="588"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="12"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="171"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="15"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="172"/>
            <end position="181"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OBZ88501.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="656" mass="72862" checksum="90A13DCAE1EA479F" modified="2016-11-30" version="1">MDFAWVSDAHKHLKNKESDQHSSDNVRRARAGTMPSSTLSPFLNLNPYIAQQKPQRSGSFSDLTDSSLDDNSTIASTLASLGLHDDPELPTMRHRAFTVSSKTYPDMTPFSPFLLDQPMMNNNPPLATHRRPRAISLGMADQKPFSPFDHFRATSNLTDDLLYNPFSHVEEAKEEENEDEGGEGHQTPSRALWLGNINSSVSVPDLHQIFSCYGRVESARILSDKECAFVNFETVESALAAKEDLVNRLGSKVKGSAVKVGFGKADVSVAMALSNEAGPNAQGPTRSLWVGNIPADINPAVLRSLFQRFGSIESIRILSHKNCGFVNFEKQEDAVRARKKLQNKEILGRGTGIVRVGFAKAPDTNDIVEDVVINGNKWSTVIWMATMMMNAQKQQLNSSSVEMDENKRLMLERLSIMEQLGYQPNGAELERAPVSYATHIPAVPEFSVDRKLSPLRLREIRKAFDNVNAVLDIEAVAVECNEEIVELCSDYIGNIIVQKLFEQCCQETKHSMLVSIAPHLASIGVHKNGTWAAQKIIDMVQTNEQAELVTQHIAPYVPLLLLDQFGNYVVQCCLRMDRNQFIFDAIVDNCWEIGQGRFGARAIRAILENSLVTKEQQIYVAAAIMQKALVLSTNANGSILLNWLLDTSGLLGQYRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NHT7</accession>
    <name>A0A1C7NHT7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">FYVE-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">A0J61_03369</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000143">
        <property type="protein sequence ID" value="OBZ88578.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NHT7"/>
    <dbReference type="STRING" id="101091.A0A1C7NHT7"/>
    <dbReference type="InParanoid" id="A0A1C7NHT7"/>
    <dbReference type="OrthoDB" id="660555at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd15760">
        <property type="entry name" value="FYVE_scVPS27p_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052113">
        <property type="entry name" value="FYVE-type_Zinc_Finger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000306">
        <property type="entry name" value="Znf_FYVE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017455">
        <property type="entry name" value="Znf_FYVE-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39490">
        <property type="entry name" value="ARRESTIN DOMAIN-CONTAINING PROTEIN D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39490:SF8">
        <property type="entry name" value="ZINC FINGER FYVE DOMAIN-CONTAINING PROTEIN 21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01363">
        <property type="entry name" value="FYVE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00064">
        <property type="entry name" value="FYVE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50178">
        <property type="entry name" value="ZF_FYVE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="FYVE-type" evidence="5">
        <location>
            <begin position="312"/>
            <end position="364"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50178"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OBZ88578.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="381" mass="44289" checksum="1CBEAE35AAF8468B" modified="2016-11-30" version="1">MSNISFLEYTISSLIQPKPEQKLKHHKSLVHANLTLKNDNRLAGTPSFSTYSDSNASCSHSSLSGYDDELELAKCRLDDIIGLYQNITKTTVKHNIANSHTTLPEQEWHRQFLQHMSTLTHHAEQLEKFSTDLLNTEIQVRQLHLLEDSIVEQLHEQEELYISRLEECHQVLRRQIELMNCLDEINHLLQGSRSSFDSSSTLCPPRHCRSSVSNLARLDDVQDRAVDRWIHRIRCQLSLKIGGSVNTGYVMHSYQHKNAREWIITGLGTTVDFKPCRYALHIRAKEHHLFRLLPKEDWVPDDQVDQCQSENCSTRFTLFQRRHHCRKCGHIVCQRHSMNRAPLLSASKIPEWHRVCSQCFEELMDFSVIEHSKNSLIDHCD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NHV9</accession>
    <name>A0A1C7NHV9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">CCR4-NOT transcription complex subunit 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">cnot1_4</name>
        <name evidence="3" type="ORF">A0J61_03353</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000142">
        <property type="protein sequence ID" value="OBZ88598.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NHV9"/>
    <dbReference type="STRING" id="101091.A0A1C7NHV9"/>
    <dbReference type="InParanoid" id="A0A1C7NHV9"/>
    <dbReference type="OrthoDB" id="1933107at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030015">
        <property type="term" value="C:CCR4-NOT core complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000932">
        <property type="term" value="C:P-body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0060090">
        <property type="term" value="F:molecular adaptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017148">
        <property type="term" value="P:negative regulation of translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000288">
        <property type="term" value="P:nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd20710">
        <property type="entry name" value="NOT1_connector"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.790">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.800">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007196">
        <property type="entry name" value="CCR4-Not_Not1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055454">
        <property type="entry name" value="CNOT1-like_NOT1_connector"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040398">
        <property type="entry name" value="Not1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13162">
        <property type="entry name" value="CCR4-NOT TRANSCRIPTION COMPLEX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13162:SF8">
        <property type="entry name" value="CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25097">
        <property type="entry name" value="ARM_Cnot1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04054">
        <property type="entry name" value="Not1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CCR4-NOT transcription complex subunit 1-like NOT1 connector" evidence="2">
        <location>
            <begin position="103"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="domain" description="CCR4-Not complex component Not1 C-terminal" evidence="1">
        <location>
            <begin position="421"/>
            <end position="779"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF04054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF25097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ88598.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="781" mass="89771" checksum="938903D8550AE228" modified="2016-11-30" version="1">MSPSPAISHINESKMKLYEMFAQKQMAPPPNLTHPAAAAAAAGGNSMGLPTSLLGNNNTNNGKLEMSDRLLVLTTLVGLFNFRSTFQSVDPFSTKVEQMLLELDRLLRQSGNLPFSLLAPHHDIILVMRQIPLLINQSAQPTLLRSVVERVIHQLYQSKASLAIEVYCRFLQSLLELSPSISKETLSWLLYSDDERKNDVWIMTSLIKFGLVPLEEYDVKLSKQLKQQSTDQSFIEFITELLQNCLLSVHPISSIEEHVLVIHTLQALDSPKAKELIQDLEKKANENHPHLSQKDAFSFRLLFAEWTRICRIPHASPSLCQQFAERILKTITCQTVDQLCFFLRLCTEACVSLYRPGRTQLVDAYAKLIGCMVSAQQNTTEQLKIASYALSVAVLVLSNQYEHQQTQFNQKPFLKLLSSLFVELHQVSCQKKQLHTQLMIVYSDVLYTLEPLQFPGFAFSWLQLLSHRHFLPLLLMLEGSDKGDRICFKLISAHLRFLNQLLSGRNRRFSVSEKAFYQGTLRFLVVILHDYPEFLCRHYHAFIQLLPVDCIQLRNVMLSSFPRTMILPNPFTTPLGYMATHASPAPELYMDPDFYSINQAGFDLSQLLDHYLSQSPSAPSLETIGRQLMVRLVQQDRLMNSEHVQQVIFYAGTQSRLDVTRSLLENPAIQIYKYLLTHLHEQRDQYWVLNAIVDHLRYPNSHTYFFSMTLMHLFSSQSETIKELMTRVLLERLIVNRPHPWGLLTTFIQLIKEPLFTEHQFIKDSVSHSPDIRRLFDNVLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NIA1</accession>
    <name>A0A1C7NIA1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_03231</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000135">
        <property type="protein sequence ID" value="OBZ88720.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NIA1"/>
    <dbReference type="STRING" id="101091.A0A1C7NIA1"/>
    <dbReference type="InParanoid" id="A0A1C7NIA1"/>
    <dbReference type="OrthoDB" id="2156690at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="100"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="143"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ88720.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="143" mass="16361" checksum="CCD76448CAD44E9F" modified="2016-11-30" version="1" fragment="single">MNPPTKKGGHPYATQSSESSSYVSLQNLGNHPNRPSILLNHDLDEQADLPEPVLPWMKSESRQSLGSQRSSIDTSSLHIMKRQIPDPSTKKKQRWTKHKWWLLLSNTLLFCYGLGILLLALLTYFKFYLRADVVIVGERMILN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NJ05</accession>
    <name>A0A1C7NJ05_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">12-oxophytodienoate reductase 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">OPR1_6</name>
        <name evidence="5" type="ORF">A0J61_04633</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the NADH:flavin oxidoreductase/NADH oxidase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000231">
        <property type="protein sequence ID" value="OBZ87304.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NJ05"/>
    <dbReference type="FunCoup" id="A0A1C7NJ05">
        <property type="interactions" value="288"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NJ05"/>
    <dbReference type="InParanoid" id="A0A1C7NJ05"/>
    <dbReference type="OrthoDB" id="276546at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016628">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd02933">
        <property type="entry name" value="OYE_like_FMN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.70:FF:000059">
        <property type="entry name" value="N-ethylmaleimide reductase, FMN-linked"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001155">
        <property type="entry name" value="OxRdtase_FMN_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045247">
        <property type="entry name" value="Oye-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22893">
        <property type="entry name" value="NADH OXIDOREDUCTASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22893:SF91">
        <property type="entry name" value="NADPH DEHYDROGENASE 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00724">
        <property type="entry name" value="Oxidored_FMN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51395">
        <property type="entry name" value="FMN-linked oxidoreductases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NADH:flavin oxidoreductase/NADH oxidase N-terminal" evidence="4">
        <location>
            <begin position="5"/>
            <end position="338"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00724"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OBZ87304.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="367" mass="40560" checksum="E6187280E459C5AC" modified="2016-11-30" version="1">MSTALFTPIKIGKSQLQHRVVLAPLTRLRASMEGVPTDLAVEYYTQRASKGGLSITEATLISRLAGGIPQAPGLYNQDQVQGWKRVTDAVHKKGAFIHAQLWHVGRTGFGMLNPNHEQIVSASDVPVRGKNEQGYDYEVPRPLEINEIKSIVQDFRQAALNAIEAGFDGVEIHGANGYLIDQFINSGSNKRTDQYGGSIQNRARFALEVVDAVADAIGAERTGIRFSPGGTYQDMHDDTEVETWGYLASELQANHPDLAYLHFVESRANFITDDPVSEDSLTPYRRIWKGPFISGGGFSTNLPHASEMAEKTGNLLSFGRAFIANPDLPERIRNGWALNKYDRSTFYGHTAAGYTDYPFYSQEKKSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NJ40</accession>
    <name>A0A1C7NJ40_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 3">Nuclear transport factor 2</fullName>
            <shortName evidence="3">NTF-2</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">NTF2</name>
        <name evidence="5" type="ORF">A0J61_02912</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Has a role in nuclear-cytoplasmic transport of proteins and mRNAs.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="3">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000117">
        <property type="protein sequence ID" value="OBZ89040.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NJ40"/>
    <dbReference type="FunCoup" id="A0A1C7NJ40">
        <property type="interactions" value="812"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NJ40"/>
    <dbReference type="InParanoid" id="A0A1C7NJ40"/>
    <dbReference type="OrthoDB" id="6507044at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005635">
        <property type="term" value="C:nuclear envelope"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051028">
        <property type="term" value="P:mRNA transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006606">
        <property type="term" value="P:protein import into nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd00780">
        <property type="entry name" value="NTF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.450.50:FF:000005">
        <property type="entry name" value="Nuclear transport factor 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.450.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045875">
        <property type="entry name" value="NTF2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032710">
        <property type="entry name" value="NTF2-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002075">
        <property type="entry name" value="NTF2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018222">
        <property type="entry name" value="Nuclear_transport_factor_2_euk"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12612">
        <property type="entry name" value="NUCLEAR TRANSPORT FACTOR 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02136">
        <property type="entry name" value="NTF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54427">
        <property type="entry name" value="NTF2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50177">
        <property type="entry name" value="NTF2_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="3" id="KW-0653">Protein transport</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="NTF2" evidence="4">
        <location>
            <begin position="7"/>
            <end position="121"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00026247"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU369002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OBZ89040.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="124" mass="13910" checksum="3C6554CFD78269F8" modified="2016-11-30" version="1">MADINQVAKAFTEFYYQTFDTNRAGLVSLYRNESMLTFEGQQFASANNIAEKLTSLPFSKVVHKVSTIDAQPSNPNGGTIIVNVTGGLLIDDNENPQLFSQTFHLIPEGSSYWVYNDIFRLCYV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NJB5</accession>
    <name>A0A1C7NJB5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Argininosuccinate synthase</fullName>
            <ecNumber evidence="3">6.3.4.5</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Citrulline--aspartate ligase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="primary">ARG1</name>
        <name evidence="14" type="ORF">A0J61_02732</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Amino-acid biosynthesis; L-arginine biosynthesis; L-arginine from L-ornithine and carbamoyl phosphate: step 2/3.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Homotetramer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="11">Belongs to the argininosuccinate synthase family. Type 1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.4.5" evidence="3"/>
    <dbReference type="EMBL" id="LUGH01000107">
        <property type="protein sequence ID" value="OBZ89203.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NJB5"/>
    <dbReference type="FunCoup" id="A0A1C7NJB5">
        <property type="interactions" value="529"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NJB5"/>
    <dbReference type="InParanoid" id="A0A1C7NJB5"/>
    <dbReference type="OrthoDB" id="1688907at2759"/>
    <dbReference type="UniPathway" id="UPA00068">
        <property type="reaction ID" value="UER00113"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004055">
        <property type="term" value="F:argininosuccinate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000053">
        <property type="term" value="P:argininosuccinate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006526">
        <property type="term" value="P:L-arginine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000050">
        <property type="term" value="P:urea cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01999">
        <property type="entry name" value="ASS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.620:FF:000019">
        <property type="entry name" value="Argininosuccinate synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.1260.10:FF:000003">
        <property type="entry name" value="Argininosuccinate synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1260.10">
        <property type="entry name" value="Argininosuccinate synthetase, chain A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00005">
        <property type="entry name" value="Arg_succ_synth_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048268">
        <property type="entry name" value="Arginosuc_syn_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048267">
        <property type="entry name" value="Arginosuc_syn_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001518">
        <property type="entry name" value="Arginosuc_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018223">
        <property type="entry name" value="Arginosuc_synth_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023434">
        <property type="entry name" value="Arginosuc_synth_type_1_subfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024074">
        <property type="entry name" value="AS_cat/multimer_dom_body"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00032">
        <property type="entry name" value="argG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF001770">
        <property type="entry name" value="PRK00509.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11587">
        <property type="entry name" value="ARGININOSUCCINATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11587:SF2">
        <property type="entry name" value="ARGININOSUCCINATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20979">
        <property type="entry name" value="Arginosuc_syn_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00764">
        <property type="entry name" value="Arginosuc_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52402">
        <property type="entry name" value="Adenine nucleotide alpha hydrolases-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69864">
        <property type="entry name" value="Argininosuccinate synthetase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00564">
        <property type="entry name" value="ARGININOSUCCIN_SYN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00565">
        <property type="entry name" value="ARGININOSUCCIN_SYN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="5" id="KW-0055">Arginine biosynthesis</keyword>
    <keyword evidence="9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0436">Ligase</keyword>
    <keyword evidence="8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Arginosuccinate synthase-like N-terminal" evidence="12">
        <location>
            <begin position="7"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="domain" description="Arginosuccinate synthase C-terminal" evidence="13">
        <location>
            <begin position="180"/>
            <end position="406"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00014810"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022571"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00029916"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00060987"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF00764"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF20979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="OBZ89203.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="411" mass="45908" checksum="9A2731F3211E3997" modified="2016-11-30" version="1">MASDKGKVLLAYSGGLDTSVILAWLIEQGYETLAYIADVGQEEDFEAIKAKALKVGASKVFVEDLKEEFVKEQIFPAIQANAIYESVYLLGTSLARPVIARKQIEIAAREGCQYVSHGCTGKGNDQVRFELAYYALKSDIQVIAPWRLPVFFERFAGRSALLDYAAEKNIHVAQTKAKPWSTDENLFHISYEAGILEDPNITPPKDMWKLTVDPEDAPNTPERITITFEQGIPVKVVNHNDGQEETEPVKLFTYLNTVARRNGIGRIDIVESRFIGVKSRGCYETPGGTILRTAHLDLEGLTLDGQLRAHRDQNITIPYGRALYNGQYFSPECEFLSKSIAFTQRNVTGDVKLKLYKGNTIVEGRVARGAGAKLYDMQESSMDEQGGYNPQDADGFIKIHSIRLKKWTPEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NJC2</accession>
    <name>A0A1C7NJC2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Biofilm and cell wall regulator 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">BCR1_0</name>
        <name evidence="12" type="ORF">A0J61_02727</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000107">
        <property type="protein sequence ID" value="OBZ89213.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NJC2"/>
    <dbReference type="STRING" id="101091.A0A1C7NJC2"/>
    <dbReference type="InParanoid" id="A0A1C7NJC2"/>
    <dbReference type="OrthoDB" id="10018191at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000433">
        <property type="term" value="P:carbon catabolite repression of transcription from RNA polymerase II promoter by glucose"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:002343">
        <property type="entry name" value="Zinc finger protein 33A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051007">
        <property type="entry name" value="creA/MIG_C2H2-ZnF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47428">
        <property type="entry name" value="REGULATORY PROTEIN MIG1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47428:SF2">
        <property type="entry name" value="ZINC FINGER PROTEIN RSV1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="7" id="KW-0804">Transcription</keyword>
    <keyword evidence="6" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 9" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="11">
        <location>
            <begin position="39"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="11">
        <location>
            <begin position="70"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="90"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="286"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="15"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="10">
        <location>
            <begin position="93"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="289"/>
            <end position="305"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="OBZ89213.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="336" mass="38648" checksum="48A413401107CB51" modified="2016-11-30" version="1">MSTGTESLHHFQPISKKDDPDYEDHQVELSRHQGKSKVFQCTGYGDCKMVFTRSEHLARHMRKHTGEKPFQCVVPGCDRMFSRFDNMMQHTQTHNKSRNGPRRNNKPKPAKRGHKKSTRRSSMMDYEDYVLPSPPPSHRGSSHHLIKEHQIIMPNPKYVELDEDDLDDISSCSSGDYYQPINLYYPPLYPSDSPTLSDTLSIHDYFPTPSRRRSAPQVRYQPYPYPVKEEREIAFIPRRNSVLSELATYLVDHPDQSPENFIRHKTMPTTRRLSVQDLANPIEQLEETSSSMSASTSNSSISSHPSLDEDDGVDLTEDEFQAIQGFGKFFRAAITL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NK52</accession>
    <name>A0A1C7NK52_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">KxDL motif-containing protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">kxd1</name>
        <name evidence="3" type="ORF">A0J61_04286</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the KXD1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000206">
        <property type="protein sequence ID" value="OBZ87664.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NK52"/>
    <dbReference type="STRING" id="101091.A0A1C7NK52"/>
    <dbReference type="InParanoid" id="A0A1C7NK52"/>
    <dbReference type="OrthoDB" id="10258877at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0099078">
        <property type="term" value="C:BORC complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032418">
        <property type="term" value="P:lysosome localization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039843">
        <property type="entry name" value="KXD1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019371">
        <property type="entry name" value="KxDL_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13511">
        <property type="entry name" value="KXDL MOTIF-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13511:SF0">
        <property type="entry name" value="KXDL MOTIF-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10241">
        <property type="entry name" value="KxDL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="KxDL" evidence="2">
        <location>
            <begin position="12"/>
            <end position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF10241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ87664.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="136" mass="15910" checksum="E98ABD03A31C9DF6" modified="2016-11-30" version="1">MTDIPHHLADQLLQLKSDQDIQDVLSDQQECLNIYEESQKKLEAFNKFSQIRYQHVHKHFEAHTKLLVEVKNDLNSVFSKIRKIKSQLASQYPNEMEAALKKHSPPVVPEEPSFVQEARMEQLGIYSRNLFSTFKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NKA9</accession>
    <name>A0A1C7NKA9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_02392</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000089">
        <property type="protein sequence ID" value="OBZ89567.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NKA9"/>
    <dbReference type="STRING" id="101091.A0A1C7NKA9"/>
    <dbReference type="InParanoid" id="A0A1C7NKA9"/>
    <dbReference type="OrthoDB" id="2141050at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39218">
        <property type="entry name" value="OXIDOREDUCTASE 14 KDA SUBUNIT, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G12110)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39218:SF1">
        <property type="entry name" value="OXIDOREDUCTASE 14 KDA SUBUNIT, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G12110)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ89567.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="81" mass="8705" checksum="364DC441527CCE62" modified="2016-11-30" version="1">MSLIGSVSGFAAFGVLVRTYALGLQKRPILSNPSSHLLAAGVFGAVGYYVHNLQERQAALMASKKEIMIKNRARAEELASQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NKH4</accession>
    <name>A0A1C7NKH4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="3">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="primary">Atr</name>
        <name evidence="15" type="ORF">A0J61_04152</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the PI3/PI4-kinase family. ATM subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="3"/>
    <dbReference type="EMBL" id="LUGH01000197">
        <property type="protein sequence ID" value="OBZ87784.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NKH4"/>
    <dbReference type="STRING" id="101091.A0A1C7NKH4"/>
    <dbReference type="InParanoid" id="A0A1C7NKH4"/>
    <dbReference type="OrthoDB" id="381190at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005694">
        <property type="term" value="C:chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000077">
        <property type="term" value="P:DNA damage checkpoint signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000723">
        <property type="term" value="P:telomere maintenance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00892">
        <property type="entry name" value="PIKKc_ATR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1070.11">
        <property type="entry name" value="Phosphatidylinositol 3-/4-kinase, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1010.10">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050517">
        <property type="entry name" value="DDR_Repair_Kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003152">
        <property type="entry name" value="FATC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057564">
        <property type="entry name" value="HEAT_ATR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000403">
        <property type="entry name" value="PI3/4_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036940">
        <property type="entry name" value="PI3/4_kinase_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003151">
        <property type="entry name" value="PIK-rel_kinase_FAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014009">
        <property type="entry name" value="PIK_FAT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11139">
        <property type="entry name" value="ATAXIA TELANGIECTASIA MUTATED ATM -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11139:SF69">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE ATR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02259">
        <property type="entry name" value="FAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02260">
        <property type="entry name" value="FATC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23593">
        <property type="entry name" value="HEAT_ATR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00454">
        <property type="entry name" value="PI3_PI4_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01343">
        <property type="entry name" value="FATC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00146">
        <property type="entry name" value="PI3Kc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51189">
        <property type="entry name" value="FAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51190">
        <property type="entry name" value="FATC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50290">
        <property type="entry name" value="PI3_4_KINASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0227">DNA damage</keyword>
    <keyword evidence="10" id="KW-0234">DNA repair</keyword>
    <keyword evidence="8 15" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-0539">Nucleus</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="FAT" evidence="13">
        <location>
            <begin position="1"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="domain" description="PI3K/PI4K catalytic" evidence="12">
        <location>
            <begin position="488"/>
            <end position="794"/>
        </location>
    </feature>
    <feature type="domain" description="FATC" evidence="14">
        <location>
            <begin position="781"/>
            <end position="817"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010769"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="OBZ87784.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="817" mass="92655" checksum="D69A8320FB81B1B2" modified="2016-11-30" version="1">MNRDIPALIGCIINEMHKNNCIEAAQLMDEARIKVIEQLTMSQSKSYRKSYPLLFNLQLIEELEESQVTSETPERAKHLENLEARWKKTFGNIVPHTQHQLDLLHLRKAAYFDIRSSDDESATISKNILLHIVSINRKAGNMIIADDALQQAEQQSNQILYRERAKLLWKKGRPKEAADLLMPRALSGEATFEEALLYVDIDLQHALEGDAKNMVKIINREGQLEGEKAEKANILCIKWYGKRLNETHEEHLQINIKTYLIKRSISALQRGSKYYYTSMSTLLNCWFDIANIGQQMRKSSTPRLTDLSKKVTDASESMLNITNVVPLYQFIVFLPRLISNLLVEDDILAGSLAKIILEVFGAYPRHTIWLMLGAIDSPVSRVRLRIRQIFEKARTKFSNSLVPAVIQDAFKLREALYELSSVKVSSGTIDMGTLGKASLLHLRDLQLHMPGERCLLPNLPEIITKSTSSYDPFGFDPCGNSLPQISRFEPTIAVMKSLQMPKRITAIGSDGKEYRFLLKKEDDLRKDARTMEFNNMINTFLKKNPEARDSGLYIRTYSVVPLGNRWGLIEWIDNLFALKAVVNEYLMADGFDGVSALAAKFDAYKLGTASEKVQGFEKVLASSPPTFYKWFLRNFPEPNQWLNSRTRFIKTLAVMSIVGYCIGLGDRHAENITFDETNGDCVHVDLNLLFEGGSSLPTPEIVPFRLTHNLVDAMGILGYSGTFKQTCELTLKVLLDNQETLLTVYETHLNELQTARDLTGKQSLRIERNPATETMNKLRAKFDTKAGQIGERVAQLIQAATSKQNLSQMYVGWAPFI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NKI2</accession>
    <name>A0A1C7NKI2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_02284</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000084">
        <property type="protein sequence ID" value="OBZ89653.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NKI2"/>
    <dbReference type="InParanoid" id="A0A1C7NKI2"/>
    <dbReference type="OrthoDB" id="2212248at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="111"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="155"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="126"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="155"/>
            <end position="170"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ89653.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="607" mass="70445" checksum="1E94F9DB624A82AF" modified="2016-11-30" version="1">MTDMDVDEAEFDHLDLDDLIKLEEEAVVVDHTLMPDQSTQPTSNMSIATSFGHLTEYGHENGQYMNLESEIRNLKHELNRMQRKLQEQDDTVKRKDQEVIGLKQQLSMLRQKTTSEKRTFPAQKPLPKKPSKRHLNTQPEMNTMKRVKMISSPSTVASSIPSTPTATTVTIPPPSPKHSVQQDLKEDYIKLLRTLYYDRLYERNKQSYIITKEARLWLTSSTRNQLTDEFLLTWMPKPENMSTDQFGTIIHEIKVILSESSLPLTLHALTHQINLCLSLANRHQLCVAIKHIVTAIYRLLEQFPSMIRILYLDLVYSPSSSLVLTLVDTLSQLGFRQQSPHAYILSDSHSLSDIKRLKKQYQFSFSEIADRLKMKRVSDESYHSTLFILDIFRHLSRNYQKPLFDFLITKNAFLDLLSTDAPLDILIRALSILKNTNFGKSQLTIDNTDEDKPLLIAQKLFDLLDIPSTRIGKEKVYQLHLDVLQVLKQLCKMNLPSSILLVVQREAYKKSMDLMRAETVEMKKLLKKAERRKQAEFIAKCFDTIHTVLKMYKEDLFDFYEQNEAYNLVCISNLVLYMFKQIPESHQAYIYVAAVEKLLNRHVQISS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NKJ6</accession>
    <name>A0A1C7NKJ6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Calcium-transporting ATPase 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">A0J61_02424</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000091">
        <property type="protein sequence ID" value="OBZ89528.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NKJ6"/>
    <dbReference type="STRING" id="101091.A0A1C7NKJ6"/>
    <dbReference type="InParanoid" id="A0A1C7NKJ6"/>
    <dbReference type="OrthoDB" id="116380at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005384">
        <property type="term" value="F:manganese ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005391">
        <property type="term" value="F:P-type sodium:potassium-exchanging transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030007">
        <property type="term" value="P:intracellular potassium ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006883">
        <property type="term" value="P:intracellular sodium ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990573">
        <property type="term" value="P:potassium ion import across plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902600">
        <property type="term" value="P:proton transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036376">
        <property type="term" value="P:sodium ion export across plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1000:FF:000028">
        <property type="entry name" value="Calcium-transporting P-type ATPase, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1000:FF:000001">
        <property type="entry name" value="Phospholipid-transporting ATPase IC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.150.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, transmembrane domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006068">
        <property type="entry name" value="ATPase_P-typ_cation-transptr_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004014">
        <property type="entry name" value="ATPase_P-typ_cation-transptr_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023299">
        <property type="entry name" value="ATPase_P-typ_cyto_dom_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018303">
        <property type="entry name" value="ATPase_P-typ_P_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023298">
        <property type="entry name" value="ATPase_P-typ_TM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008250">
        <property type="entry name" value="ATPase_P-typ_transduc_dom_A_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059000">
        <property type="entry name" value="ATPase_P-type_domA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050510">
        <property type="entry name" value="Cation_transp_ATPase_P-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001757">
        <property type="entry name" value="P_typ_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044492">
        <property type="entry name" value="P_typ_ATPase_HD_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01494">
        <property type="entry name" value="ATPase_P-type"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43294:SF20">
        <property type="entry name" value="P-TYPE ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43294">
        <property type="entry name" value="SODIUM/POTASSIUM-TRANSPORTING ATPASE SUBUNIT ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13246">
        <property type="entry name" value="Cation_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00689">
        <property type="entry name" value="Cation_ATPase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00690">
        <property type="entry name" value="Cation_ATPase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00122">
        <property type="entry name" value="E1-E2_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08282">
        <property type="entry name" value="Hydrolase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00119">
        <property type="entry name" value="CATATPASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00121">
        <property type="entry name" value="NAKATPASE"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG00002">
        <property type="entry name" value="C1.7:_P-type_atpase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00003">
        <property type="entry name" value="Haloacid_Dehalogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00027">
        <property type="entry name" value="p-type_atpase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00831">
        <property type="entry name" value="Cation_ATPase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81653">
        <property type="entry name" value="Calcium ATPase, transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81665">
        <property type="entry name" value="Calcium ATPase, transmembrane domain M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81660">
        <property type="entry name" value="Metal cation-transporting ATPase, ATP-binding domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00154">
        <property type="entry name" value="ATPASE_E1_E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-1278">Translocase</keyword>
    <keyword evidence="2 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="295"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="463"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="497"/>
            <end position="520"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="1000"/>
            <end position="1025"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="1072"/>
            <end position="1099"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="1142"/>
            <end position="1160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="1172"/>
            <end position="1191"/>
        </location>
    </feature>
    <feature type="domain" description="Cation-transporting P-type ATPase N-terminal" evidence="10">
        <location>
            <begin position="219"/>
            <end position="294"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00038148"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM00831"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="OBZ89528.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="1205" mass="133719" checksum="77A0558695537E46" modified="2016-11-30" version="1">MSLKPPIQESISHAVVDLFSINDGKLSVEQQIEIYVNDLFMVHENKSISLDDVLEGLIYVMEYRIRNGFQPHLDLGLMKRLSEGLFLNMSLTEGHWIRKRPTKQSDKAFSLFGDFLQEVNEFRTVISELDVSQLRSQLKLHYRCQPSSSEDQKMSVIKVIFTLAHFFPHQYGDWHELIKESEQNDLERLLKSPLAEKFREGNRQPMSPQELVLFPPQALYFDRSVEKLLKMFTHTDPVQGLSSDIIPTLREHYGTNQLPKPPRPNALKMIWEQLTDFIVLILIAAAIVEAAEKEFNSMIVLLVVVVLNTVIGFSQEWKASKTLNALMNLSVPQAHVVRDGQESWIDSEELVPGDIVVLEEGDAVPADLRLIEVAQLNVVEGILTGESLPVQKTVNIVKAKTGKIPLGDCKGNAFMSTNVSNGRAKGLVVRTGLKTEIGKISTAIQNGSKKKVKTPIQRKLTRLGIYLVAMALFLCALVVAIGVAWKHDARDMVHIGLSLAVSVIPEGLVAVTTVTMALGVRRMALKKCIVRTLPAVESLGSVTVICSDKTGTLTEGKMGAAELWTTDDALYKFTESTSMDPQAGQIIQESEELRRRMIHVRRTVASPDNKSNLPVDCSTMLPKPLDTSATSSYSNQMYYAMMISSLCNNSDIRRDEETGEMKSIGDPTEVALTVAAQKAKVGRSYWNQQMKLTKLFERAFDSERKLMSSVYQQKETTQEKLIETTDYVMLCKGAPEELLRKCNRYMSREENPMHRLVSAQPTELITDHFASQIHDENNRMASQGLRVLGLAYKVVKDIKESNTDEDIEHATGESANAKYQSNPAFAEEDLIFVGLIGLIDPPKAGVKEAIETCQNAGIQVIMITGDHVETATAIAKQLGIFKADVSGMSRAILGRELDLISDDAILELNPFPSVFARVSPNNKLSIVSALQKRGELVAMTGDGVNDAPAIKNADIGVAMGIAGTEITKQAADIVLVDDNFTSIVHAVEEGRHVFDNILKFIVYLLSCNGAEIFLMLICTTANITVPLSVMMILWANIIADIPPAMALGIEPNEADLMQRDPRDPKMGVITKVTWLVIAMNSLIIAALALAVHCLNLFVLNFPIEIARSSTFTALTTVQLVHSFNARSIHRSIFKTGITNNKWMIGAFLLSFCLMILGIYTPGLSDWLNLVPVGWQTWVMTIACVVFLIVFVELEKMGLRRMTGKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NKK0</accession>
    <name>A0A1C7NKK0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Tether containing UBX domain for GLUT4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">ASPSCR1</name>
        <name evidence="3" type="ORF">A0J61_02298</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000084">
        <property type="protein sequence ID" value="OBZ89667.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NKK0"/>
    <dbReference type="STRING" id="101091.A0A1C7NKK0"/>
    <dbReference type="InParanoid" id="A0A1C7NKK0"/>
    <dbReference type="OrthoDB" id="440781at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012506">
        <property type="term" value="C:vesicle membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd16118">
        <property type="entry name" value="UBX2_UBXN9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001012">
        <property type="entry name" value="UBX_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46467">
        <property type="entry name" value="TETHER CONTAINING UBX DOMAIN FOR GLUT4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46467:SF1">
        <property type="entry name" value="TETHER CONTAINING UBX DOMAIN FOR GLUT4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00789">
        <property type="entry name" value="UBX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50033">
        <property type="entry name" value="UBX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UBX" evidence="2">
        <location>
            <begin position="76"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="180"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="186"/>
            <end position="210"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ89667.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="221" mass="24962" checksum="3BA7589FE1FE13AB" modified="2016-11-30" version="1">MSTSNEQEAAFDRQIKVLRPPASAGPTAELPESAYKLSPNEIKQLYQSTVERRERLENSPLKTQKMRDKEEFEKLKKYPKTTIRIRMPNHTVVQAVFESKETVGALYDFVRSCLETPERKFVLCLPPRTKLTEPSITLFKAGLSPASNVLFGWIEKANEDADAMLRKEYMDMIEDMASVASPQSSPPIASTLSSTSTSSSTESKSKPIPKWLQKGLFNRKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NKN5</accession>
    <name>A0A1C7NKN5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="8">40S ribosomal protein S10-B</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">rps10b_2</name>
        <name evidence="8" type="ORF">A0J61_02240</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the eukaryotic ribosomal protein eS10 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000082">
        <property type="protein sequence ID" value="OBZ89692.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NKN5"/>
    <dbReference type="FunCoup" id="A0A1C7NKN5">
        <property type="interactions" value="598"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NKN5"/>
    <dbReference type="InParanoid" id="A0A1C7NKN5"/>
    <dbReference type="OrthoDB" id="5211809at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022627">
        <property type="term" value="C:cytosolic small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.10:FF:000025">
        <property type="entry name" value="40S ribosomal protein S10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005326">
        <property type="entry name" value="Plectin_eS10_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037447">
        <property type="entry name" value="Ribosomal_eS10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12146">
        <property type="entry name" value="40S RIBOSOMAL PROTEIN S10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12146:SF0">
        <property type="entry name" value="RIBOSOMAL PROTEIN S10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03501">
        <property type="entry name" value="S10_plectin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4 8" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Plectin/eS10 N-terminal" evidence="7">
        <location>
            <begin position="3"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="92"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="107"/>
            <end position="135"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF03501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OBZ89692.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="145" mass="16516" checksum="B45CCE1213055DD5" modified="2016-11-30" version="1">MLVSKQNRKVIYEALFKDGALVAPKDYNAPKHVDLDVPNLEVIKVMQSLTSKGLVKTQFSWQWYYYTLTDEGIDYLREYLHLPQEIVPATLKKSARPAAPRRAFGGEGRENRGPRGDRGDYRRKEGASGDFKPEFRGGLGRGNRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NL48</accession>
    <name>A0A1C7NL48_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Vacuolar protein sorting-associated protein 74</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">vps74</name>
        <name evidence="7" type="ORF">A0J61_02084</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Golgi apparatus membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
            <orientation evidence="1">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the GOLPH3/VPS74 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000074">
        <property type="protein sequence ID" value="OBZ89873.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NL48"/>
    <dbReference type="FunCoup" id="A0A1C7NL48">
        <property type="interactions" value="214"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NL48"/>
    <dbReference type="InParanoid" id="A0A1C7NL48"/>
    <dbReference type="OrthoDB" id="2189106at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005797">
        <property type="term" value="C:Golgi medial cisterna"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005802">
        <property type="term" value="C:trans-Golgi network"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019899">
        <property type="term" value="F:enzyme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070273">
        <property type="term" value="F:phosphatidylinositol-4-phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030968">
        <property type="term" value="P:endoplasmic reticulum unfolded protein response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007030">
        <property type="term" value="P:Golgi organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043001">
        <property type="term" value="P:Golgi to plasma membrane protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048194">
        <property type="term" value="P:Golgi vesicle budding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006487">
        <property type="term" value="P:protein N-linked glycosylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035269">
        <property type="term" value="P:protein O-linked glycosylation via mannose"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045053">
        <property type="term" value="P:protein retention in Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0060304">
        <property type="term" value="P:regulation of phosphatidylinositol dephosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006890">
        <property type="term" value="P:retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.3630.10:FF:000004">
        <property type="entry name" value="Probable VPS74-protein involved in protein-vacuolar targeting"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3630.10">
        <property type="entry name" value="yeast vps74-n-term truncation variant domain like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008628">
        <property type="entry name" value="GPP34-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038261">
        <property type="entry name" value="GPP34-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12704:SF2">
        <property type="entry name" value="GOLGI PHOSPHOPROTEIN 3 HOMOLOG SAURON"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12704">
        <property type="entry name" value="TRANS-GOLGI PROTEIN GMX33"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05719">
        <property type="entry name" value="GPP34"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="4" id="KW-0446">Lipid-binding</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="31"/>
            <end position="44"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OBZ89873.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="317" mass="35623" checksum="1E724F01C779FA24" modified="2016-11-30" version="1">MSTVTRRRVAGHANSDDDNHNSTDSSNTSPRTDKKIAYDPRDIDESKSTPKLTLMEEVLLLGLKDKQGYLSFWNDSISYALRGCIVIELALRGRIAMVKDSNRRKYPLCDRHIEVINDSLTGEVLLDEALKMMKISEKMSVSNWIDLMSGETWNVMKIGYQLKQVRERLAKGLVDKGVLRTEKRNFLLFDMATHPVADPAVKEEIIKRVCTMLVTRVSPASIDAQSELPHAYIRTVSMICAAYAANVLENALLYLQPDLREQAFTKVDELMNDYSSWPFTGSQGKVDIPTGTDLSLEVVASVLNVLARMDAIVSEFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NLH9</accession>
    <name>A0A1C7NLH9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Vacuolar protein sorting-associated protein 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">vps1_1</name>
        <name evidence="9" type="ORF">A0J61_01931</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="5">Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000067">
        <property type="protein sequence ID" value="OBZ90031.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NLH9"/>
    <dbReference type="FunCoup" id="A0A1C7NLH9">
        <property type="interactions" value="32"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NLH9"/>
    <dbReference type="InParanoid" id="A0A1C7NLH9"/>
    <dbReference type="OrthoDB" id="5061070at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005777">
        <property type="term" value="C:peroxisome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008017">
        <property type="term" value="F:microtubule binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006897">
        <property type="term" value="P:endocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048312">
        <property type="term" value="P:intracellular distribution of mitochondria"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000266">
        <property type="term" value="P:mitochondrial fission"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016559">
        <property type="term" value="P:peroxisome fission"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007033">
        <property type="term" value="P:vacuole organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd08771">
        <property type="entry name" value="DLP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000473">
        <property type="entry name" value="Vacuolar sorting-associated 1 protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1240">
        <property type="entry name" value="Dynamin, middle domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022812">
        <property type="entry name" value="Dynamin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001401">
        <property type="entry name" value="Dynamin_GTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019762">
        <property type="entry name" value="Dynamin_GTPase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045063">
        <property type="entry name" value="Dynamin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000375">
        <property type="entry name" value="Dynamin_stalk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030381">
        <property type="entry name" value="G_DYNAMIN_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003130">
        <property type="entry name" value="GED"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020850">
        <property type="entry name" value="GED_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11566">
        <property type="entry name" value="DYNAMIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11566:SF220">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01031">
        <property type="entry name" value="Dynamin_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00350">
        <property type="entry name" value="Dynamin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02212">
        <property type="entry name" value="GED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00195">
        <property type="entry name" value="DYNAMIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00053">
        <property type="entry name" value="DYNc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00302">
        <property type="entry name" value="GED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00410">
        <property type="entry name" value="G_DYNAMIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51718">
        <property type="entry name" value="G_DYNAMIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51388">
        <property type="entry name" value="GED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="3" id="KW-0505">Motor protein</keyword>
    <keyword evidence="1 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Dynamin-type G" evidence="8">
        <location>
            <begin position="26"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="domain" description="GED" evidence="7">
        <location>
            <begin position="607"/>
            <end position="693"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="530"/>
            <end position="567"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="543"/>
            <end position="555"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00073589"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51388"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51718"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OBZ90031.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="693" mass="77346" checksum="A98DA2E020631145" modified="2016-11-30" version="1">MSMDSQLIKTVNKLQDAFATVGVHNPVDLPQIAVIGSQSSGKSSVLENIVGRDFLPRGTGIVTRRPLILQLINRPADASKEQDSEEITNGNPHEWGEFLHLPGQKFYDFGKIREEIVKDTELKTGKNLGISPQPINLRIFSPNVLTLTLVDLPGLTKVPVGDQPKDIEKQIREMILKYITKPNSIILAVTGANTDLANSDGLKLARDVDPEGLRTIGVLTKVDLMDQGTDVIDILAGRVIPLRLGYVPVVNRGQRDIESNKSIKRALDAEREFFESHPAYKSKAQYCGTPFLARKLNMILMHHIRNTLPEIKAKIQSALLKYQQELAALGDPLDEDGSTANRANLVLNIITEFCTEFRTIIDGNSNDLSSFELSGGARISFVFHEIYANGVKSIDPLEQIKDDDIRIILYNSSGSTPALFVATTAFEVIIKKQIKRLEEPSIKCINIVYDELVRILGQLLTKQFFKRFPTLKEKFYQVVLAFFKKALQPTSKLVSDMVLMEACYINTAHPDLLNGHQAVAAVNERIMQKNQQQIEAAPHKQSKNSAPNSLQTSNGAPEESSSNGSLFGSFFSGNKKNTKKSPTSMMDTPPTTLKATGALSDREFMEIQVTKMLIQSYFNIVKRTMIDMVPKAIMLNLVNRSKEELQRELLAELYKHDVLDDLLQESDSTRQRRKECKKMIEALQKADEIVGSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NLQ8</accession>
    <name>A0A1C7NLQ8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_01958</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000069">
        <property type="protein sequence ID" value="OBZ89985.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NLQ8"/>
    <dbReference type="InParanoid" id="A0A1C7NLQ8"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="44"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="47"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ89985.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="112" mass="13197" checksum="A8DF91AF46EE1D5D" modified="2016-11-30" version="1">MHEETFLPSNYVKALTQTEKQVQILVAVHQTKRILDFALELPPDNLESADEEEEEEVDPQNDAEDFRNLLLYIDSFKYITDDVKNNQHQPVSYQCFNEEISYWITFGLGQRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NMW2</accession>
    <name>A0A1C7NMW2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Repressor of filamentous growth 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">RFG1</name>
        <name evidence="6" type="ORF">A0J61_03340</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000142">
        <property type="protein sequence ID" value="OBZ88604.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NMW2"/>
    <dbReference type="STRING" id="101091.A0A1C7NMW2"/>
    <dbReference type="InParanoid" id="A0A1C7NMW2"/>
    <dbReference type="OrthoDB" id="6247875at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001228">
        <property type="term" value="F:DNA-binding transcription activator activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030154">
        <property type="term" value="P:cell differentiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01389">
        <property type="entry name" value="HMG-box_ROX1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.30.10">
        <property type="entry name" value="High mobility group box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009071">
        <property type="entry name" value="HMG_box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036910">
        <property type="entry name" value="HMG_box_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050140">
        <property type="entry name" value="SRY-related_HMG-box_TF-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10270:SF161">
        <property type="entry name" value="SEX-DETERMINING REGION Y PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10270">
        <property type="entry name" value="SOX TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00505">
        <property type="entry name" value="HMG_box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00398">
        <property type="entry name" value="HMG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47095">
        <property type="entry name" value="HMG-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50118">
        <property type="entry name" value="HMG_BOX_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0804">Transcription</keyword>
    <feature type="domain" description="HMG box" evidence="5">
        <location>
            <begin position="259"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="HMG box" evidence="3">
        <location>
            <begin position="259"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="122"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="330"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="146"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="348"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="375"/>
            <end position="385"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OBZ88604.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="385" mass="43126" checksum="2F922404DE77FFE0" modified="2016-11-30" version="1">MLSINHPYIYSPKEEVSYMTEHQRRYPVPTPPPSSASPIELAPILDMCDSTDNRPLSPDSPKLKKFPLSSDGHFGPHLAHLAHPPPFLEPMPVLQSPQSQTGFFSLELFKVFKNKSTIPKLQIPIPRRSRPVNTHFKPTLKDSIPSLSSSSSSTSSTSSSSLTYDDHDMISTPMSPIMAAASASAAAAAAHRHPGSQVAKSLLKSIQPSTVNSGLKRSFGMLEDDDTFSTSSSDDHDFHPSYKKSNVDQSMFLTKNAHIKRPRNAWIHFRCHYGQALKSQDPTLRAEEISKRASRRWSKLTESEKKPWHGLAEQEKLAHREAFPEYRYCPRRANSSSSPPSTPVPHATVNNNHGRPRSVSDSQTPLHMHDVFHRNNQKRMKRCSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NNH8</accession>
    <name>A0A1C7NNH8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Cytochrome c oxidase assembly protein COX20, mitochondrial</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">cox20</name>
        <name evidence="10" type="ORF">A0J61_01263</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the COX20 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000038">
        <property type="protein sequence ID" value="OBZ90671.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NNH8"/>
    <dbReference type="FunCoup" id="A0A1C7NNH8">
        <property type="interactions" value="178"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NNH8"/>
    <dbReference type="InParanoid" id="A0A1C7NNH8"/>
    <dbReference type="OrthoDB" id="14603at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033617">
        <property type="term" value="P:mitochondrial respiratory chain complex IV assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022533">
        <property type="entry name" value="Cox20"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31586:SF1">
        <property type="entry name" value="CYTOCHROME C OXIDASE ASSEMBLY PROTEIN COX20, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31586">
        <property type="entry name" value="CYTOCHROME C OXIDASE PROTEIN 20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12597">
        <property type="entry name" value="Cox20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR02049">
        <property type="entry name" value="PROTEINF36A"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="35"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="59"/>
            <end position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009575"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00017689"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OBZ90671.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="135" mass="15086" checksum="3C9F6F06E55B22F8" modified="2016-11-30" version="1">MSSSEQENPRFVDALKTVKLDDFKDVNKIPCARNALLYGIGTGVALGMLRFFSRRSIPTAANWAVGSFCGVSVVSFEYCQWERRQKLDKLKLIVKATDSKPKPDERMTVTERGKNGAFNVVIETPTSLEQPKKDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NNI6</accession>
    <name>A0A1C7NNI6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">NAD(P)-binding protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">A0J61_01384</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000043">
        <property type="protein sequence ID" value="OBZ90568.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NNI6"/>
    <dbReference type="FunCoup" id="A0A1C7NNI6">
        <property type="interactions" value="56"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NNI6"/>
    <dbReference type="InParanoid" id="A0A1C7NNI6"/>
    <dbReference type="OrthoDB" id="6251714at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016616">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000047">
        <property type="entry name" value="NADP-dependent L-serine/L-allo-threonine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42901">
        <property type="entry name" value="ALCOHOL DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42901:SF1">
        <property type="entry name" value="ALCOHOL DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OBZ90568.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="259" mass="28184" checksum="87E49D211724D04B" modified="2016-11-30" version="1">MGRLQGKTVFITGASAGIGEATARQFADEGCNLVITARRLEKLEQLKSELNKSYPNIYVHATQLDVRSKQEIDKVVAELPAQVKDIDVLINNAGMVIGLDPLVEVEEEVVDQMLATNVKGLIFLTKAIVPQMKQRGTGHVINIGSIAGKQAYAGGSIYCATKFAVDAITKSLAIELVDTPVRVSQICPGLVNTEFSTVRFRGDKEKADSVYKGIQPLVADDIAELIVFTASRPAHVNIQDMLVFPTNQADSKTVYRRPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NPB3</accession>
    <name>A0A1C7NPB3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_02852</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000114">
        <property type="protein sequence ID" value="OBZ89094.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NPB3"/>
    <dbReference type="InParanoid" id="A0A1C7NPB3"/>
    <dbReference type="OrthoDB" id="2235387at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ89094.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="109" mass="12771" checksum="2E1DF56D476317C4" modified="2016-11-30" version="1">MTTQMNFNESSREELPQFTSQEYASEQSYFNDYDQEMINAVNEADCYDYPKEEEDVYIIDEGLLKLILDVQSYLAEAPQDSPLFALQYKMYTYLRQRASELGMDVSSLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NPC0</accession>
    <name>A0A1C7NPC0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="1">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">ppk13_1</name>
        <name evidence="11" type="ORF">A0J61_00974</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="1"/>
    <dbReference type="EMBL" id="LUGH01000026">
        <property type="protein sequence ID" value="OBZ90962.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NPC0"/>
    <dbReference type="FunCoup" id="A0A1C7NPC0">
        <property type="interactions" value="446"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NPC0"/>
    <dbReference type="InParanoid" id="A0A1C7NPC0"/>
    <dbReference type="OrthoDB" id="248923at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005773">
        <property type="term" value="C:vacuole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032889">
        <property type="term" value="P:regulation of vacuole fusion, non-autophagic"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006624">
        <property type="term" value="P:vacuolar protein processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd13986">
        <property type="entry name" value="STKc_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052239">
        <property type="entry name" value="Ser/Thr-specific_kinases"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45998">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE 16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45998:SF2">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE 16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 11" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="10">
        <location>
            <begin position="32"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="60"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="OBZ90962.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="368" mass="41046" checksum="D07AF11B393747E2" modified="2016-11-30" version="1">MTSPLASVLDLFSSFVGCCIPSSNLSINGKAYRIVKLLGEGGFSFVYLAQDGSGNLYAMKKIRCTLGTEEAELAQKEVDIYQLFSHPNVIRMLDSSTITESDGSKTIYIFLPYYKRGNLQDVINKNNLNKTHFTEADMLRIFRQVCIAVQYLHTYKAKGGARVMYEPSQVMSAEEENRQDEALLNGHQEQPSGEQIETGKRGEIVPWAHRDIKPGNVLMSDDGETPILMDFGSACPARVSIETRQDALRQQDLAAEQSTMPYRAPELFDVKTGTTLDEKVDIWSLGCTLYAMAYGSSPFEVNMDQGGSVALAVLNNQYKFPQDSPYSSELNEVISWMLTANPANRPNIHQIISKLDQLLETYQNTTEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NPI5</accession>
    <name>A0A1C7NPI5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Aurora kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">aurK</name>
        <name evidence="8" type="ORF">A0J61_00905</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000024">
        <property type="protein sequence ID" value="OBZ91027.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NPI5"/>
    <dbReference type="STRING" id="101091.A0A1C7NPI5"/>
    <dbReference type="InParanoid" id="A0A1C7NPI5"/>
    <dbReference type="OrthoDB" id="410920at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24345:SF0">
        <property type="entry name" value="CELL CYCLE SERINE_THREONINE-PROTEIN KINASE CDC5_MSD2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24345">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE PLK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 8" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="7">
        <location>
            <begin position="1"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="59"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="69"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="109"/>
            <end position="118"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OBZ91027.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="363" mass="41573" checksum="DEF1462E2FDE3ED4" modified="2016-11-30" version="1">MTAISSDCSMRVNYENNTRLNPRKTRKDEDDEDWKRLSSNKPPLPFLLPRPENKDKNSDSMTSVHLTPSVSQSSETSASSSIRISHSFEKDNQPSSSLHPHPYQKAPLSPSQTKSTPSLTLMKEKDNISTSYIPLFEWPVHSLSSEPQFDPELQFNEPKSKTVFSEMIDMVCRLLQEPASYPKDIYLVFDENEHMKGITFIMQDGTREDYLKFGGSLQYLAPELIDDDSSAYDYEYMEVWSLGVSLFRMLIGKYPFKSDVSSDRELFKRMAMANLDIPKQISEDAKDLIQKMLSPRHSRVSLNSVQSHPWLEEHIPEEETDPPPKNQKGKKVGHLLLQAFRLITQGPYPPPASYYDLAQIKSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NPP4</accession>
    <name>A0A1C7NPP4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_01060</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000030">
        <property type="protein sequence ID" value="OBZ90879.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NPP4"/>
    <dbReference type="InParanoid" id="A0A1C7NPP4"/>
    <dbReference type="OrthoDB" id="2419780at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025271">
        <property type="entry name" value="CCDC28"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13270">
        <property type="entry name" value="CCDC28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ90879.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="111" mass="12988" checksum="41F24D4D1AB642B7" modified="2016-11-30" version="1">MEAHEHVMQHLNEEFKKVDKAFQSHQLGVFGKDTDRLFKELDIIRRKQIDLASEHVSLESIHDIPLSKSNQTTATTSDRQFEKKEIMLKSMMAKLDDLTQAMERFKQISKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NQ59</accession>
    <name>A0A1C7NQ59_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">tRNA dimethylallyltransferase</fullName>
            <ecNumber evidence="5">2.5.1.75</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">tit1</name>
        <name evidence="7" type="ORF">A0J61_00787</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>adenosine(37) in tRNA + dimethylallyl diphosphate = N(6)-dimethylallyladenosine(37) in tRNA + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:26482"/>
            <dbReference type="Rhea" id="RHEA-COMP:10162"/>
            <dbReference type="Rhea" id="RHEA-COMP:10375"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57623"/>
            <dbReference type="ChEBI" id="CHEBI:74411"/>
            <dbReference type="ChEBI" id="CHEBI:74415"/>
            <dbReference type="EC" id="2.5.1.75"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the IPP transferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.75" evidence="5"/>
    <dbReference type="EMBL" id="LUGH01000020">
        <property type="protein sequence ID" value="OBZ91168.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NQ59"/>
    <dbReference type="FunCoup" id="A0A1C7NQ59">
        <property type="interactions" value="571"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NQ59"/>
    <dbReference type="InParanoid" id="A0A1C7NQ59"/>
    <dbReference type="OrthoDB" id="775260at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052381">
        <property type="term" value="F:tRNA dimethylallyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006400">
        <property type="term" value="P:tRNA modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.20.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00185">
        <property type="entry name" value="IPP_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039657">
        <property type="entry name" value="Dimethylallyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018022">
        <property type="entry name" value="IPT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00174">
        <property type="entry name" value="miaA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11088">
        <property type="entry name" value="TRNA DIMETHYLALLYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11088:SF89">
        <property type="entry name" value="TRNA DIMETHYLALLYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01715">
        <property type="entry name" value="IPPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6 7" id="KW-0808">Transferase</keyword>
    <keyword evidence="5" id="KW-0819">tRNA processing</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003783"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003785"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OBZ91168.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="464" mass="53965" checksum="B54BFE943D0C5102" modified="2016-11-30" version="1">MSAIRKIAAVVGSSGIGKSKLAVELCKALKGQVINADALQVYKGLDIITNKMPLSEREGIKHHLMDFLEPEEEYRITSFLKDASQRIESISEEKQLPVVVGGTHYYVQSLLWNNTTIEEERASSEDEDTQFPEFDLLETEELYQQLKQVDPIMANKWHPSDRRKILRSLRVLLTDQIEKFWTKTDKSYWRVFHQTGKPQSEIIKSQKEHFELHGLVPRYKALVFWIYSDPDQLNPRLDARVDQMIDVGLFDEIKDLRNRVREGSVKMPGVELERYQRGLWQAIGYKEFDPYFVALEEGKEGKELDDIKHECTERVKSATRKYAKSQIKWIRNKLLPAALNAKNNDVMIYCLDATDLEHWDQNVKDKAVEVAKAFEQGQPLPDPKSLSNMAATMLTPTQAIKDVQTKILTWNKHVCDTCKDNKGEPLVLNGDKEWEQHKKSRFHRKYLKHLKMEALRKAHFEKRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NQM4</accession>
    <name>A0A1C7NQM4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_00696</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000017">
        <property type="protein sequence ID" value="OBZ91250.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NQM4"/>
    <dbReference type="InParanoid" id="A0A1C7NQM4"/>
    <dbReference type="OrthoDB" id="2140426at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="136"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="184"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="19"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="19"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ91250.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="210" mass="23916" checksum="34244E667426008E" modified="2016-11-30" version="1">MTARPVNDDFSYRLTESILSQSPSPQPGMTPSHVGPLPSNAIVAQPQDNNASFNHYLGNHFKEDAPVLLDRLKAPHDRMPQKKQSESTFWTHFSNDHPGRNTTISSQHELMGENTWNHSGAFGPGGQHTYATATTFFSLGAFLFLFGFVFPPLWWIGSFYPVYIDERYQRRYDPNVKMAKRWRLLNRFFSLGFSAFLVVAIIVLAILYSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NR40</accession>
    <name>A0A1C7NR40_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Inner spore coat protein H</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">cotH_2</name>
        <name evidence="2" type="ORF">A0J61_00372</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000008">
        <property type="protein sequence ID" value="OBZ91573.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NR40"/>
    <dbReference type="STRING" id="101091.A0A1C7NR40"/>
    <dbReference type="InParanoid" id="A0A1C7NR40"/>
    <dbReference type="OrthoDB" id="10267127at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014867">
        <property type="entry name" value="Spore_coat_CotH_CotH2/3/7"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40050">
        <property type="entry name" value="INNER SPORE COAT PROTEIN H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40050:SF1">
        <property type="entry name" value="INNER SPORE COAT PROTEIN H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08757">
        <property type="entry name" value="CotH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0167">Capsid protein</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0946">Virion</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008889838" evidence="1">
        <location>
            <begin position="20"/>
            <end position="577"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ91573.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="577" mass="65464" checksum="80A3669B79CF5316" modified="2016-11-30" version="1">MVMLKKLPFVFGLLSLVSAGQQNELIDYSVVGAIDNAHSMAVVVDNTTYLLIADKGSSALHTGQAPIAKFGYQYVKIDKNKNLTESVESFLRKPVSENTVYEFFNRTWNTRQIAKLPQVYKPLNAIHRIKSDLHKDGQIPTISIEGSQADFDVLHSNTTCEDCKVNTNVTYIGLKEKYRFENVRVTLAGRSSTSMSKLSYNIKLKKKDRLFDYRRVKLRAMATDPSYLREQLAYDVIESVGLVSSQFSFCRLLINNKDVGLFGIIDTFQDSWLANVFAEGDKEYENGNLYQGIFQSAESARVHRGSDLDFYNGNLTAYQDGQYKVKVNAHGEKEDNYKPLMDFTEFVANAPTEGPKAVKAWKKRLDVDSFLRSMALEKIMGYSDGYSTMADNYYILQLPKTNKFFWISSDMDMTLGNTVAYLDDMLSGDYKSYPGLMARPLTSKVLSIKEFRDQFNNLIREISEKLVNPVTMNKRINDMVSMLREDVEWDQSLPRLGETVLFDSVNSSSISESPYYFEKVNLNLTVAGDFATRLNGVPFDIAINGPIGRISLTGLKEWIQKSSENIKAFYKETSHQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NSD8</accession>
    <name>A0A1C7NSD8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Ubiquitin carboxyl-terminal hydrolase</fullName>
            <ecNumber evidence="1">3.4.19.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">Usp4_1</name>
        <name evidence="5" type="ORF">A0J61_01704</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).</text>
            <dbReference type="EC" id="3.4.19.12"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase C19 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.19.12" evidence="1"/>
    <dbReference type="EMBL" id="LUGH01000057">
        <property type="protein sequence ID" value="OBZ90234.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NSD8"/>
    <dbReference type="FunCoup" id="A0A1C7NSD8">
        <property type="interactions" value="525"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NSD8"/>
    <dbReference type="InParanoid" id="A0A1C7NSD8"/>
    <dbReference type="OrthoDB" id="292964at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004843">
        <property type="term" value="F:cysteine-type deubiquitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016579">
        <property type="term" value="P:protein deubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02674">
        <property type="entry name" value="Peptidase_C19R"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.70.10">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2230.10">
        <property type="entry name" value="DUSP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035927">
        <property type="entry name" value="DUSP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006615">
        <property type="entry name" value="Pept_C19_DUSP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001394">
        <property type="entry name" value="Peptidase_C19_UCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050185">
        <property type="entry name" value="Ub_carboxyl-term_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028889">
        <property type="entry name" value="USP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018200">
        <property type="entry name" value="USP_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21646">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06337">
        <property type="entry name" value="DUSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00443">
        <property type="entry name" value="UCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00695">
        <property type="entry name" value="DUSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143791">
        <property type="entry name" value="DUSP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51283">
        <property type="entry name" value="DUSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00972">
        <property type="entry name" value="USP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00973">
        <property type="entry name" value="USP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50235">
        <property type="entry name" value="USP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0645">Protease</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0788">Thiol protease</keyword>
    <keyword evidence="1" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="DUSP" evidence="4">
        <location>
            <begin position="35"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="domain" description="USP" evidence="3">
        <location>
            <begin position="336"/>
            <end position="965"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU366025"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51283"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OBZ90234.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="966" mass="110653" checksum="7F7E9DC590FB6B9B" modified="2016-11-30" version="1">MDPKEHFRKKRAQPETDLNANGKRHRSYPPESISRDTNMQLEIISQLKLKKDTESESRVISGKWYVQWEGYCLGMKPRPSAVDNSTIMDANNQLKGGLEEGTDRFTVSVEIWNTLVSWYGLIDPSHELLVTNGDCQKDDVKPASANPIPSLGKIKKISNKPKIYKKKEDKPALHSQQVLQQFINKPQSEDPMYQFKVYRVGQSTERGRSFAISASCSVLEFQSTLLNALDIPLREKDSVKLWLLNNQNTYLLQKLEDSAPFVVSDQLLSSDKNRTAHQIDTSTIPTTSSLASCLFQIMPSTTKDFYLAVDYVKNKPAKPSSSKSTPASRTKTLGLTGLQNLGNTCYMNSAIQCLSNTNKLTEWFANNQYKQDLNTNNPLGLNGELAKAYAALLADIWKPSTTFTTFMRSSVSPREFKSTFERFNPHFAGYMQQDSQELLSFLLDGLHEDLNRVLEKPYIEIPDFDSQEFSDTEIAHHFWQYHKARNDSIIVDLFQGQYKSRLICDECQKVSVTFDPFMHISVPLPRKTKTPSTYEINVIYVPYTPSQKHLKMKISLSKEATIENLQKEVQNNLASLSLMPNNDHNLLVTEIHDEKIYKVFDSEELVDLIQPSDQIYVYQLPCSLLDQKWVVFPVYCSTPLLTARAELDDVFPIRQFGYPIIIAMKKNDLQDYSNLYTTIASHIERYCVVKLFEEDTSAEVVQSPIQVQSNGSQSPIHTTAAVTPAGGRPMVPMPNLFQIKVFQYHQRNKRFNFPQGSDTGSWKEVNNQDAIVEQGQGVVIEWKLSKAQQMFSASVLSKKIDAWNDFDVSDKDEDKEVTLQDCLDEFAGDELLTSQDSWYCPQCKKHQHASKKMDIWRLPEIMIIHLKRFSQFRRWEETKLDTFVDFPLIGLDMSKMVLGPHEHELIYDLYAVDNHYGGMGGGHYTAFAQNFLNGEWYEFNDTHVTRMEAQDVKTSAAYILFYKRRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NUJ0</accession>
    <name>A0A1C7NUJ0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">very-long-chain enoyl-CoA reductase</fullName>
            <ecNumber evidence="4">1.3.1.93</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">A0J61_00799</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="19 20" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19 20">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="16">Catalyzes the last of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme reduces the trans-2,3-enoyl-CoA fatty acid intermediate to an acyl-CoA that can be further elongated by entering a new cycle of elongation. Thereby, it participates in the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="15">
            <text>a very-long-chain 2,3-saturated fatty acyl-CoA + NADP(+) = a very-long-chain (2E)-enoyl-CoA + NADPH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:14473"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:83724"/>
            <dbReference type="ChEBI" id="CHEBI:83728"/>
            <dbReference type="EC" id="1.3.1.93"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Lipid metabolism; fatty acid biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the steroid 5-alpha reductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="19">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.3.1.93" evidence="4"/>
    <dbReference type="EMBL" id="LUGH01000020">
        <property type="protein sequence ID" value="OBZ91164.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NUJ0"/>
    <dbReference type="FunCoup" id="A0A1C7NUJ0">
        <property type="interactions" value="75"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NUJ0"/>
    <dbReference type="InParanoid" id="A0A1C7NUJ0"/>
    <dbReference type="OrthoDB" id="540503at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102758">
        <property type="term" value="F:very-long-chain enoyl-CoA reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042761">
        <property type="term" value="P:very long-chain fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01801">
        <property type="entry name" value="Ubl_TECR_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.120.1630:FF:000010">
        <property type="entry name" value="Steroid alpha reductase family protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1630">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001104">
        <property type="entry name" value="3-oxo-5_a-steroid_4-DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039357">
        <property type="entry name" value="SRD5A/TECR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049127">
        <property type="entry name" value="TECR-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000626">
        <property type="entry name" value="Ubiquitin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10556">
        <property type="entry name" value="3-OXO-5-ALPHA-STEROID 4-DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10556:SF28">
        <property type="entry name" value="VERY-LONG-CHAIN ENOYL-COA REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02544">
        <property type="entry name" value="Steroid_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21696">
        <property type="entry name" value="TECR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50244">
        <property type="entry name" value="S5A_REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50053">
        <property type="entry name" value="UBIQUITIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="14" id="KW-0275">Fatty acid biosynthesis</keyword>
    <keyword evidence="8" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="5" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="12" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="13 17" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0521">NADP</keyword>
    <keyword evidence="11" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 17" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10 17" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="162"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="193"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="250"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="domain" description="Ubiquitin-like" evidence="18">
        <location>
            <begin position="1"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007742"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012530"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00051495"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00058640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS50053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="OBZ91164.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="303" mass="35272" checksum="FF7DCE4526677D70" modified="2016-11-30" version="1">MKVTIAARNSKSSKFPVTLELSGTPESLKTSDLNKALHQKFPTYYPDRQRLTTEDKKALDVDKTLKEQGITEETTVYFKDLGPQIGWRTVFMIEYAGPLVIHPIFYYLSKTIYGSSFTHSRMQEVTYYMVMAHFLKRELETLFVHRFSHGTMPFFNVFKNSAHYWFLSGINLAFWVYGPWFSQGKGLAVRSDVWIYGSVAVWVWAQLSNLITHITLRNLRPAGTRVRAIPYGYGFDLVSCPNYFFEFIGWTAVCFLTTSWSAFLFNIVATGQMYIWAVKKHKNYKKEFKEYPRNRAAMFPFIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NVF7</accession>
    <name>A0A1C7NVF7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Acyl-CoA-binding domain-containing protein 4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">ACBP4_2</name>
        <name evidence="4" type="ORF">A0J61_00486</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000011">
        <property type="protein sequence ID" value="OBZ91454.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NVF7"/>
    <dbReference type="STRING" id="101091.A0A1C7NVF7"/>
    <dbReference type="InParanoid" id="A0A1C7NVF7"/>
    <dbReference type="OrthoDB" id="10251809at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.80">
        <property type="entry name" value="Kelch-type beta propeller"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015915">
        <property type="entry name" value="Kelch-typ_b-propeller"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006652">
        <property type="entry name" value="Kelch_1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46093">
        <property type="entry name" value="ACYL-COA-BINDING DOMAIN-CONTAINING PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46093:SF18">
        <property type="entry name" value="FIBRONECTIN TYPE-III DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01344">
        <property type="entry name" value="Kelch_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24681">
        <property type="entry name" value="Kelch_KLHDC2_KLHL20_DRC7"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00612">
        <property type="entry name" value="Kelch"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117281">
        <property type="entry name" value="Kelch motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0880">Kelch repeat</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="52"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="80"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="117"/>
            <end position="126"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OBZ91454.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="494" mass="55951" checksum="A51808C182443EE6" modified="2016-11-30" version="1">MLSHSRSQKSFPETASYHSLPRNQTSPNGFEQNAYLRSESPTLPPEVHTPESQSSSFSSNEYSRDLTTTSSKYHTHRSNESNFVSPTSTYDSTYSQKEDESYQPTRQESRSRKHRQSVPTPSQPTKTRLVHTKPSYHQIRTPDHLATAIEISTTNKISTIAPAAGMYWSRLLTYGRGPSRPLRAHTANLIGEKLYVFGGCDTSLCFNSLYVLDMDTLTWTKPRTANQSIPPPCRAHSCTVVERNLGFDRKSYQLYIFGGGNGPDYFQDVYRLDLDTMVWSKPNIDPHSRPPKRRAHTTCLWENKVIVIGGGDGARALDDVYMLDISDPDCPMLSWKKMETSGPSPPARGYHTSNLIKDKLIVFGGSDGHDCFDDIYVLDLKEQRWTEIEVDRKIKRLAHTSTQVGSYVFVIGGHDGKRYSQEVLMFNLVTMNWEAKKVYGSPPHPRGYHTTVLYDSRLYVLGGYDGKNVFDDVHMLELSACAYLPQITNFEIDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NVL9</accession>
    <name>A0A1C7NVL9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Ribosome maturation protein SDO1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">sbds</name>
        <name evidence="12" type="ORF">A0J61_00417</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="7">Associates with the 60S ribosomal subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the SDO1/SBDS family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000009">
        <property type="protein sequence ID" value="OBZ91524.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NVL9"/>
    <dbReference type="FunCoup" id="A0A1C7NVL9">
        <property type="interactions" value="554"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NVL9"/>
    <dbReference type="InParanoid" id="A0A1C7NVL9"/>
    <dbReference type="OrthoDB" id="10253092at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990932">
        <property type="term" value="F:5.8S rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005085">
        <property type="term" value="F:guanyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070180">
        <property type="term" value="F:large ribosomal subunit rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042134">
        <property type="term" value="F:rRNA primary transcript binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070181">
        <property type="term" value="F:small ribosomal subunit rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042256">
        <property type="term" value="P:cytosolic ribosome assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1250.10:FF:000001">
        <property type="entry name" value="SBDS, ribosome maturation factor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1250.10">
        <property type="entry name" value="Ribosome maturation protein SBDS, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.900">
        <property type="entry name" value="SBDS protein C-terminal domain, subdomain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018023">
        <property type="entry name" value="Ribosome_mat_SBDS_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036786">
        <property type="entry name" value="Ribosome_mat_SBDS_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002140">
        <property type="entry name" value="Sdo1/SBDS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039100">
        <property type="entry name" value="Sdo1/SBDS-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046928">
        <property type="entry name" value="SDO1/SBDS_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018978">
        <property type="entry name" value="SDO1/SBDS_central"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037188">
        <property type="entry name" value="Sdo1/SBDS_central_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019783">
        <property type="entry name" value="SDO1/SBDS_N"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00291">
        <property type="entry name" value="RNA_SBDS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10927">
        <property type="entry name" value="RIBOSOME MATURATION PROTEIN SBDS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10927:SF1">
        <property type="entry name" value="RIBOSOME MATURATION PROTEIN SBDS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20268">
        <property type="entry name" value="SBDS_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09377">
        <property type="entry name" value="SBDS_domain_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01172">
        <property type="entry name" value="SBDS_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89895">
        <property type="entry name" value="FYSH domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109728">
        <property type="entry name" value="Hypothetical protein AF0491, middle domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01267">
        <property type="entry name" value="UPF0023"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0690">Ribosome biogenesis</keyword>
    <feature type="domain" description="Ribosome maturation protein SDO1/SBDS N-terminal" evidence="9">
        <location>
            <begin position="42"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="domain" description="Ribosome maturation protein SDO1/SBDS central" evidence="10">
        <location>
            <begin position="137"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="domain" description="Ribosome maturation protein SDO1/SBDS C-terminal" evidence="11">
        <location>
            <begin position="202"/>
            <end position="271"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00049708"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00071414"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF09377"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF20268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="OBZ91524.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="281" mass="32482" checksum="2E8194216E492961" modified="2016-11-30" version="1">MNATELRKNAIFQNNSVLDYRCGHFGYNMVIQQPNTQIKLTNVSIVRLRKGGKRFELACYKNKVMEWRSNVETDLDEVLQIHNVFLNVSKGQVASKEDLKKCFKTEEVDKVIQEILKKGELQVAEKERTDQLETIWKDIANIVTDNCVNPQTKRPYTVTMIEKAMQDLHLSVNPKRSPKSQALDVIKQLQEKQLLPIQRAQMRLRLTLAQSSASKKLREKIMPLLTSIEDEDSNESEIEIIALIDPGQYRIINDLLQKEGKGKGQLEIMNLREKEEGDERF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7LKV5</accession>
    <name>A0A1C7LKV5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">CCHC-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">A0J61_11934</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01002726">
        <property type="protein sequence ID" value="OBZ65372.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="InParanoid" id="A0A1C7LKV5"/>
    <dbReference type="OrthoDB" id="2264205at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.60.10">
        <property type="entry name" value="Zinc finger, CCHC-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001878">
        <property type="entry name" value="Znf_CCHC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036875">
        <property type="entry name" value="Znf_CCHC_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00098">
        <property type="entry name" value="zf-CCHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00343">
        <property type="entry name" value="ZnF_C2HC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57756">
        <property type="entry name" value="Retrovirus zinc finger-like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50158">
        <property type="entry name" value="ZF_CCHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="CCHC-type" evidence="3">
        <location>
            <begin position="134"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="151"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="164"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="194"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="222"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OBZ65372.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="222" mass="25156" checksum="2DBAE596AE9A28F1" modified="2016-11-30" version="1" fragment="single">MVWSSQKKRTRILPCPSIDANYNIITVSLTHLPFVHPDEIGTGLAKSLTPFGEIIDVGITTEPKLGVFMGSGYAVLGRPQNSNFLELAHTVSWCESEDQFFHCTWNNMPTWCRYCHQTGHTKFECEKSKARIICYSCQQFGHRSFECPRKIASPAQKKRKGPIPRRETTEKDYQPSNEXLKSQHAPRDXILPKSQPSLTLDDSMPSLNENTTLKGQSSFIDN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MTE6</accession>
    <name>A0A1C7MTE6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Aspartic peptidase DDI1-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_11818</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01002534">
        <property type="protein sequence ID" value="OBZ80133.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7MTE6"/>
    <dbReference type="InParanoid" id="A0A1C7MTE6"/>
    <dbReference type="OrthoDB" id="2289688at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00303">
        <property type="entry name" value="retropepsin_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.70.10">
        <property type="entry name" value="Acid Proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021109">
        <property type="entry name" value="Peptidase_aspartic_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13650">
        <property type="entry name" value="Asp_protease_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50630">
        <property type="entry name" value="Acid proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="191"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ80133.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="191" mass="21124" checksum="EB5B1AAFF235CA23" modified="2016-11-30" version="1" fragment="single">MIETPNYLTSLTQIAGLSPAARTMIKAALTKPQENPRNRRNQAIHSTNLYIEDDHFGHEDVFENHEEIIDMNSNRNQISLPHGNGAPRTFGTVNGVECEMILDFGCTLFVISXRLALEIGITDVKRTETELLLGDGKIAKPLGVIENLNIEVGGTVSATITAICLDVSDRYDFIIGRIGLHLLHRSKINHV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MTQ3</accession>
    <name>A0A1C7MTQ3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_11700</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01002365">
        <property type="protein sequence ID" value="OBZ80251.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MTQ3"/>
    <dbReference type="InParanoid" id="A0A1C7MTQ3"/>
    <dbReference type="OrthoDB" id="2202621at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="114"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ80251.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="114" mass="13340" checksum="5976EA61F39C8310" modified="2016-11-30" version="1" fragment="single">MKESNITIKHDICPHGCYLYLVRHTDLTQCQADDCNLPRYRNSLQYDLERNDVNRDPTMSLPELMPNRQITYTSIGKALTELWADDEKLDILNYGHDFLSDNYENSTGYKDVFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MUS7</accession>
    <name>A0A1C7MUS7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">SWR1 complex bromodomain subunit bdf1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">bdf1</name>
        <name evidence="6" type="ORF">A0J61_11316</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001901">
        <property type="protein sequence ID" value="OBZ80635.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MUS7"/>
    <dbReference type="FunCoup" id="A0A1C7MUS7">
        <property type="interactions" value="753"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7MUS7"/>
    <dbReference type="InParanoid" id="A0A1C7MUS7"/>
    <dbReference type="OrthoDB" id="784962at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000785">
        <property type="term" value="C:chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006338">
        <property type="term" value="P:chromatin remodeling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.920.10">
        <property type="entry name" value="Bromodomain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050935">
        <property type="entry name" value="Bromo_chromatin_reader"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001487">
        <property type="entry name" value="Bromodomain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036427">
        <property type="entry name" value="Bromodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027353">
        <property type="entry name" value="NET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038336">
        <property type="entry name" value="NET_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22880:SF225">
        <property type="entry name" value="BROMODOMAIN-CONTAINING PROTEIN BET-1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22880">
        <property type="entry name" value="FALZ-RELATED BROMODOMAIN-CONTAINING PROTEINS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17035">
        <property type="entry name" value="BET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00439">
        <property type="entry name" value="Bromodomain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00503">
        <property type="entry name" value="BROMODOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00297">
        <property type="entry name" value="BROMO"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47370">
        <property type="entry name" value="Bromodomain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50014">
        <property type="entry name" value="BROMODOMAIN_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51525">
        <property type="entry name" value="NET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0103">Bromodomain</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Bromo" evidence="4">
        <location>
            <begin position="42"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="domain" description="Bromo" evidence="4">
        <location>
            <begin position="209"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="domain" description="NET" evidence="5">
        <location>
            <begin position="358"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="298"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="337"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="342"/>
            <end position="359"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OBZ80635.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="465" mass="54360" checksum="AE896250A88C9C3C" modified="2016-11-30" version="1">MSKTNHSIQKSHTILPSPPIYQHTMMTPDQQKYCSAIMRNLKKHRDAAPFLNPVDYVKLNVLDYPSVIKRPMHLLLVDKKLNNTEYANVEDFISDVRLIFNNCFKYNGPEAMISVLCQNVESAFEKSLRQMPPSTPIISPKKELSPPLSHSSQQEYFTKPISEDLNRPKREIHCPSKDYPETYTTQKKRQMSAEMKFCLQTLRELKKAKYRSIAYPFLQPVDYVALNIPDYPTIVQQPMDLSTIERKLMNHEYANADMFESDITLMFNNCYLYNPPTLPIYKMAKDYEKVFQQKWNEKPREDKKRQKRKAKEPIEESEEDDRIAELERHIASISEQIASIKSAKKPRRNPPAKRKKPTKARSTEEEEFTFEQKKDLSEMINELTGDKLDTVVSIIQSSMPNLQGNGQQEIELDIDALDIQTLRRLYEFVNPKVKTTKKKVKRAKPNLKDQLEDYGKHLEIHDIQT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-09-13" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MV88</accession>
    <name>A0A1C7MV88_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">TFIIS N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_11170</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001736">
        <property type="protein sequence ID" value="OBZ80781.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MV88"/>
    <dbReference type="InParanoid" id="A0A1C7MV88"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ80781.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="61" mass="7007" checksum="6A5F6B14D5CFD010" modified="2016-11-30" version="1">MTGQEKGVENISYFVQTKQCGDESEILFVLCLCVSLMNSNDYIKTKAMRLVEIWKERASEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MWQ6</accession>
    <name>A0A1C7MWQ6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_10718</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001338">
        <property type="protein sequence ID" value="OBZ81233.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MWQ6"/>
    <dbReference type="InParanoid" id="A0A1C7MWQ6"/>
    <dbReference type="OrthoDB" id="10333799at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ81233.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="229" mass="26178" checksum="B8ECBBF8D60AAA62" modified="2016-11-30" version="1">MLSIAQKTTDPIIQSLVHSFISLANEITVPSIPNLSEMHIQSSFIHPLLRGVLKPLPSLVPHCSNKFAFENDHHIMHCRPDYRVDMYDQTGIYDGTNLFGELKPADATVDDVTRDFHKCMCLGKVALKCFNYDFSMTFYSVGTSVHFYLHHSLNSHITYALHLHSFQIFTTHDTFSNYASLVPILYRLSQIFRLFCTSQPKNYIPLSSTVPYPAIKEAIRSNKKRKLGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MX55</accession>
    <name>A0A1C7MX55_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Nucleus export protein BRR6</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">BRR6</name>
        <name evidence="3" type="ORF">A0J61_10544</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001228">
        <property type="protein sequence ID" value="OBZ81407.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MX55"/>
    <dbReference type="InParanoid" id="A0A1C7MX55"/>
    <dbReference type="OrthoDB" id="5961at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031965">
        <property type="term" value="C:nuclear membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055088">
        <property type="term" value="P:lipid homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006998">
        <property type="term" value="P:nuclear envelope organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040202">
        <property type="entry name" value="Brl1/Brr6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018767">
        <property type="entry name" value="Brl1/Brr6_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28136:SF1">
        <property type="entry name" value="NUCLEUS EXPORT PROTEIN BRL1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28136">
        <property type="entry name" value="NUCLEUS EXPORT PROTEIN BRR6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10104">
        <property type="entry name" value="Brr6_like_C_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01042">
        <property type="entry name" value="Brr6_like_C_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="153"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="domain" description="Brl1/Brr6" evidence="2">
        <location>
            <begin position="156"/>
            <end position="267"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM01042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ81407.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="267" mass="29804" checksum="753B218F7BD40B46" modified="2016-11-30" version="1">MDDPCSDPMDFEYTNLGSFFGHTKANNNFEVPASFFDEGKSKKSLTNTVCNLLDNFSLSEKQQEQKKQEETLLSEIAPKSPTQATLSGTFETNNALVPIQQASVQTTPSPPQTMQFSCPVEQTNIPPSYSPTFIINAPPQTLISSSEHQKGTIVYLTGLFKLALLSITFSSVMYIAFQVVCFISHDMKVKTASFESGVLADQLYCQHQYDINRCAPHTRLPAVQHLCREWEQCMYRPMDVSKSQILAETLASMLNTFVNTLSLKSLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MX84</accession>
    <name>A0A1C7MX84_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_10894</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001493">
        <property type="protein sequence ID" value="OBZ81056.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MX84"/>
    <dbReference type="InParanoid" id="A0A1C7MX84"/>
    <dbReference type="OrthoDB" id="5068804at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ81056.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="60" mass="6833" checksum="8C79220541F44F4E" modified="2016-11-30" version="1" fragment="single">PRHVKDRLALEGVLQFLENFVPETEMDMQAVQNSLKTVKTLQAKISAQRANQAKITDSFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MXD9</accession>
    <name>A0A1C7MXD9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Quinone oxidoreductase PIG3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">TP53I3</name>
        <name evidence="4" type="ORF">A0J61_10385</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001147">
        <property type="protein sequence ID" value="OBZ81565.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MXD9"/>
    <dbReference type="STRING" id="101091.A0A1C7MXD9"/>
    <dbReference type="InParanoid" id="A0A1C7MXD9"/>
    <dbReference type="OrthoDB" id="203908at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070402">
        <property type="term" value="F:NADPH binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016651">
        <property type="term" value="F:oxidoreductase activity, acting on NAD(P)H"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05276">
        <property type="entry name" value="p53_inducible_oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="ER"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014189">
        <property type="entry name" value="Quinone_OxRdtase_PIG3"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02824">
        <property type="entry name" value="quinone_pig3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48106:SF18">
        <property type="entry name" value="QUINONE OXIDOREDUCTASE PIG3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48106">
        <property type="entry name" value="QUINONE OXIDOREDUCTASE PIG3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0521">NADP</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Enoyl reductase (ER)" evidence="3">
        <location>
            <begin position="10"/>
            <end position="329"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OBZ81565.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="335" mass="36873" checksum="C7381D86EF355DF6" modified="2016-11-30" version="1">MRAVLVKSPGDASQLYLGEHEKPVPKDHEVLVKVKCFALNRMDLLQREGKYPVPPGASPILGVEVSGVVESVGKEVTNFQPGQAVFGLMPGGGYAQYAVLHEALTMHKPDALSFEQAAAIPETWFTAYQALFFVGQLKKGQDVLIHAGASGVGIAAIQLAKDAGAHRIFVTVGSEEKAKFCESIGATKAINYKTENWSDLVLKETSKKGVNLVIDFIGKDYWNQNIDVLGLDGHMVILAFMSGTLIEKFDISVMLRKRLKIEGSNLRARSVDYQAKLRDAIYQHAVSNHFAKPEDGSLKVFIDKVFNWQDIVDAHQYLESNQSMGKIVIQVTENQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-06-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MXG2</accession>
    <name>A0A1C7MXG2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_10852</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001447">
        <property type="protein sequence ID" value="OBZ81099.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MXG2"/>
    <dbReference type="InParanoid" id="A0A1C7MXG2"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008889346" evidence="1">
        <location>
            <begin position="31"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ81099.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="60" mass="6911" checksum="027B6B55FEDA3E95" modified="2016-11-30" version="1">MTTLVKQLFHKLLHLLMSFIFLHNIRPTDSYYVALGSHKRSATSQSGSATRGDKRFYLLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MXW3</accession>
    <name>A0A1C7MXW3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_10225</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001079">
        <property type="protein sequence ID" value="OBZ81725.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="InParanoid" id="A0A1C7MXW3"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.60.10">
        <property type="entry name" value="Zinc finger, CCHC-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ81725.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="154" mass="17609" checksum="0899484E9860417C" modified="2016-11-30" version="1">MSDSPAVLYAACNEPGHSRRTYRFCRMSPCNQSDEDVQMEQVQQEQTRNDVVVCSACNEPGHXRRTFAGCRMNPRFQNMEVDEQLPTIEVCANCGMKGHLRRTSRLCPFSTQNTRNIARDLSAVPSMRFDCGSMSCVCDRCGALMWIRRKGFWQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-06-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MY55</accession>
    <name>A0A1C7MY55_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_10199</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001068">
        <property type="protein sequence ID" value="OBZ81753.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MY55"/>
    <dbReference type="InParanoid" id="A0A1C7MY55"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ81753.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="65" mass="6420" checksum="C38D4912C9C313B7" modified="2016-11-30" version="1" fragment="single">MAGTAKATPEIKLRLTPEVSLVPVEGRAELAAEAAELTAEETAAPAEPAAEVIAAPTEVAAVGAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MYG4</accession>
    <name>A0A1C7MYG4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_10121</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001042">
        <property type="protein sequence ID" value="OBZ81831.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7MYG4"/>
    <dbReference type="InParanoid" id="A0A1C7MYG4"/>
    <dbReference type="OrthoDB" id="2281581at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="10"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="323"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ81831.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="323" mass="35071" checksum="B06D2FC2EA81F151" modified="2016-11-30" version="1" fragment="single">MNFTNADFATGTVSTGSVGTNPDKSTTTITTTTTSTTGPATTTTTSGPATAIPTTTKTNTTTPLSTLRRQLPSRGSTKRSRKAMGAADGQPLVESNHPNRLQNKIYLPSPSLLPTYPHYTIFRRXGTTLNSINKRPSQQISNRNXQPVHTGLLQSYVCYPKKGWWLXTSFQLKESQQLCRHTTLQDGNFKRGLIVTSAERLPNLNRSIGCIPPHPDTPITQKIPTISLEPTDISIQNNTIRLIRSSLAFYQSLSSDLRMGTSTGDSDKRIHRXLDHHCGESSTSSGTYQANTPSVVVVGLEGQPKEITSATYSTVGTPGLPIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MYG5</accession>
    <name>A0A1C7MYG5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">glucan 1,3-beta-glucosidase</fullName>
            <ecNumber evidence="14">3.2.1.58</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="15">Exo-1,3-beta-glucanase D</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="20" type="primary">exgD_1</name>
        <name evidence="20" type="ORF">A0J61_10075</name>
    </gene>
    <organism evidence="20 21">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="20 21" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="20 21">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">Glucosidase involved in the degradation of cellulosic biomass. Active on lichenan.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>Successive hydrolysis of beta-D-glucose units from the non-reducing ends of (1-&gt;3)-beta-D-glucans, releasing alpha-glucose.</text>
            <dbReference type="EC" id="3.2.1.58"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 16">Belongs to the glycosyl hydrolase 5 (cellulase A) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="20">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.58" evidence="14"/>
    <dbReference type="EMBL" id="LUGH01001022">
        <property type="protein sequence ID" value="OBZ81877.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MYG5"/>
    <dbReference type="FunCoup" id="A0A1C7MYG5">
        <property type="interactions" value="23"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7MYG5"/>
    <dbReference type="InParanoid" id="A0A1C7MYG5"/>
    <dbReference type="OrthoDB" id="62120at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009986">
        <property type="term" value="C:cell surface"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004338">
        <property type="term" value="F:glucan exo-1,3-beta-glucosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009251">
        <property type="term" value="P:glucan catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001547">
        <property type="entry name" value="Glyco_hydro_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050386">
        <property type="entry name" value="Glycosyl_hydrolase_5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31297:SF34">
        <property type="entry name" value="GLUCAN 1,3-BETA-GLUCOSIDASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31297">
        <property type="entry name" value="GLUCAN ENDO-1,6-BETA-GLUCOSIDASE B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00150">
        <property type="entry name" value="Cellulase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="11" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="9" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="10 16" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="5 16" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8 18" id="KW-0472">Membrane</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0735">Signal-anchor</keyword>
    <keyword evidence="4 18" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 18" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="62"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="domain" description="Glycoside hydrolase family 5" evidence="19">
        <location>
            <begin position="181"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="89"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="17">
        <location>
            <begin position="90"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="20">
        <location>
            <position position="262"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004401"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00036824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00037126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00038929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00041260"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="RuleBase" id="RU361153"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="Pfam" id="PF00150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="OBZ81877.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="262" mass="29798" checksum="699758588DCB533C" modified="2016-11-30" version="1" fragment="single">MKGMQNPTDINPEVKHYMNQAESVSTRSLSSQEDSIDKYKPTDVEKNQETYWQRFKQNKTRVALLVTLAVLLLLTVIIVPVVMTGLVSRDPTNQPRTVSPSPNSTRDAFDDSAQANPFTPPLNQSFQYVKEPIRGINLGGWLVLEPFITPKLFDQFSPSAVDEWHLCQALGPEEAKRQLTNHYNTFITEADFKRIAEMGFNHVRIPTGHWAVQAIEGEPFVPHISWEYLLKGIQWARKYGLRVMVELHTAPGSQNGWNHSGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MYK2</accession>
    <name>A0A1C7MYK2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 9">Mediator of RNA polymerase II transcription subunit 14</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8 9">Mediator complex subunit 14</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="primary">MED14</name>
        <name evidence="12" type="ORF">A0J61_10035</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Component of the Mediator complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the Mediator complex subunit 14 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001008">
        <property type="protein sequence ID" value="OBZ81917.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MYK2"/>
    <dbReference type="STRING" id="101091.A0A1C7MYK2"/>
    <dbReference type="InParanoid" id="A0A1C7MYK2"/>
    <dbReference type="OrthoDB" id="205099at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070847">
        <property type="term" value="C:core mediator complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016592">
        <property type="term" value="C:mediator complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003712">
        <property type="term" value="F:transcription coregulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055122">
        <property type="entry name" value="Med14_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013947">
        <property type="entry name" value="Mediator_Med14"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12809">
        <property type="entry name" value="MEDIATOR COMPLEX SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12809:SF2">
        <property type="entry name" value="MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08638">
        <property type="entry name" value="Med14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 9" id="KW-0010">Activator</keyword>
    <keyword evidence="7 9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 9" id="KW-0804">Transcription</keyword>
    <keyword evidence="4 9" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Mediator complex subunit MED14 N-terminal" evidence="11">
        <location>
            <begin position="33"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="690"/>
            <end position="712"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="12">
        <location>
            <position position="786"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007813"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00019619"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00032007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU365082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF08638"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="OBZ81917.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="786" mass="90748" checksum="E52939BA5C7607F2" modified="2016-11-30" version="1" fragment="single">MHPTMTTSNGTSHLDEPSKDKEKIVLPVEMASMVPLRTLIAKLVHKSYADLLTLTDTLPSMSDVEKKRRILTYSLSVRKQFLKLLVLIKWAENAEDIQMCQNIMAFLANQNKIFQDTVDYLHNIHSKLPAARLRNFDIPTAVDVLTTGTYQRMPTKIKDMMAPVPLSDQEVLETFQNMNDVIRMRMITTEVLPSPMQTYRIENGRIYFTIQNEFEVALTLMGHSHDRRWWIVSLDMLVQATSTGGAAEDVDITLNETQKQHLRVNAQKQLVPPPSMESNSLFFPLVNMYDYLHLCCLNMQLEVLYIQAAMLAKTRWINQLKVQMNPDRTKLTLIYWRGGSHASRWASRSNSDKSTTIEISVNDQEDPEEDYQMAVRDDWHGVIQKAGIGASIHLSELPVQDRSRVLSLLKYPKTTLSVLWDGYELKDHGLDPSDLNLERLVLQTTHDHGACMIDKFRSLLLSQRAFLEENGLFLDTTSTSQLVVRYRHAKYISIDTDTRTGRIKAFEADDGCHEGDFKLRGLEDRLNNDPENIARHLLWLRSEVVVREVIALAKQLNLQPYHPSQMNLRPEDIQKLFGDLVPDGVKEVSYPSHCVFLQFSQFEDWYFCMATVKNQFKSWLCCINKTYDATGLYQTIVDLAHLNSDQLWSGQFKQTSPTMERETLKREIKEEDEKEEGVLPGLKKRRTSRFLLPTKERDEEEDGGEPIKKEEDEKVDRLSIDLRYLAKLDSLCQAYIINRKIESQLQSYKGSLKYHTRPLLKTINRMETQVRNHPAAEKMEVICVSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MYM7</accession>
    <name>A0A1C7MYM7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_11727</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01002394">
        <property type="protein sequence ID" value="OBZ80224.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MYM7"/>
    <dbReference type="STRING" id="101091.A0A1C7MYM7"/>
    <dbReference type="InParanoid" id="A0A1C7MYM7"/>
    <dbReference type="OrthoDB" id="10260794at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052584">
        <property type="entry name" value="U2_snRNP_Complex_Component"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12785">
        <property type="entry name" value="SPLICING FACTOR 3B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12785:SF6">
        <property type="entry name" value="SPLICING FACTOR 3B SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="97"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="23"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="54"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ80224.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="177" mass="20325" checksum="2D2792E9C437A720" modified="2016-11-30" version="1">MSAVAATQKDTILNQKDAEAKAQHHKARRRNKKKSKKQRQEEEAQRKALQSQQTEDEQVPDDVEIEYVVQPVDMSQLKTMDGLSSLDENTLQQFSDIFKHFQTGKPEDNDEEFPVLDNTAQPSEDKAQDDSDDEEGKDSDQPLSKKKMKKIQRLTVAELKQLVKKPEVVEVSLRIYV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MYM8</accession>
    <name>A0A1C7MYM8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">PH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_09999</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000998">
        <property type="protein sequence ID" value="OBZ81950.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MYM8"/>
    <dbReference type="STRING" id="101091.A0A1C7MYM8"/>
    <dbReference type="InParanoid" id="A0A1C7MYM8"/>
    <dbReference type="OrthoDB" id="185175at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00821">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001849">
        <property type="entry name" value="PH_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00169">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00233">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50003">
        <property type="entry name" value="PH_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PH" evidence="2">
        <location>
            <begin position="124"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="275"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="303"/>
            <end position="315"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ81950.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="328" mass="37512" checksum="ECA62601C01605C8" modified="2016-11-30" version="1">MEFPPTIKDKELFRLSINSQSSDTTTTTNTSSQRLSVASLEEDAYNASSLHNPSSLSPSSRYLLSGFSTSENLRNKVLSRFYPSSSSSQRHQKSLSDPYIHTTMEDTINSIEPWCMSAKTALESCMLSGWMQKYETPTFAFSRSWKPRMFVLLDRILFVFKSNKLTNPAREYFVLTEDTFVFVTEEFKKGYVIELRKPLCKWFIRCESIDQMKQWLEAMKKIVACIKIGYDGLLNEAILKSITLTDDYRILIPSHIKKSYRQSLPLSLDCQLSRQGSLQPKKKKGKRQSLAEIPDWESTIPSQLPPPTTKPPPVPLAYNNDLPTVSED</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MYT1</accession>
    <name>A0A1C7MYT1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">holo-[acyl-carrier-protein] synthase</fullName>
            <ecNumber evidence="1">2.7.8.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">aasdhppt</name>
        <name evidence="5" type="ORF">A0J61_10022</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.8.7" evidence="1"/>
    <dbReference type="EMBL" id="LUGH01001004">
        <property type="protein sequence ID" value="OBZ81928.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MYT1"/>
    <dbReference type="STRING" id="101091.A0A1C7MYT1"/>
    <dbReference type="InParanoid" id="A0A1C7MYT1"/>
    <dbReference type="OrthoDB" id="26719at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008897">
        <property type="term" value="F:holo-[acyl-carrier-protein] synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019878">
        <property type="term" value="P:lysine biosynthetic process via aminoadipic acid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.470.20">
        <property type="entry name" value="4'-phosphopantetheinyl transferase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008278">
        <property type="entry name" value="4-PPantetheinyl_Trfase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037143">
        <property type="entry name" value="4-PPantetheinyl_Trfase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055066">
        <property type="entry name" value="AASDHPPT_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050559">
        <property type="entry name" value="P-Pant_transferase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12215:SF10">
        <property type="entry name" value="L-AMINOADIPATE-SEMIALDEHYDE DEHYDROGENASE-PHOSPHOPANTETHEINYL TRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12215">
        <property type="entry name" value="PHOSPHOPANTETHEINE TRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22624">
        <property type="entry name" value="AASDHPPT_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01648">
        <property type="entry name" value="ACPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56214">
        <property type="entry name" value="4'-phosphopantetheinyl transferase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="4'-phosphopantetheinyl transferase N-terminal" evidence="4">
        <location>
            <begin position="87"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="domain" description="4'-phosphopantetheinyl transferase" evidence="3">
        <location>
            <begin position="204"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="320"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00013172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01648"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF22624"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OBZ81928.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="320" mass="37270" checksum="C443FAA3110898D5" modified="2016-11-30" version="1" fragment="single">MYTFGEVDHDYKDALDLKHKATGPIAKDHNVKQTAINMAFDTVEDVEGFTSAVFKAKSERVFTVEPNFLLPRKQEELFVDYSAFEGDKFNKALSWLPDNEHTSVTRFKFERDRQLALASRLLRRHYFCQLLNKPWHDLEFEQVSGGKPFLKINNEVKYDYNTSHEGNWVIFGCVRDDMLIGVDVVSIDRPFSIDSFIKSFEPQARESIIWGLKESYIKALGVGLMLDLQNLDFYNQENKIHMRLNGKQADGWVFHLSYLDHSTLAVVCYGYREGLGQHSRALLRLYPDSYLIGEPLHELNHVFHRIQLMDIENNSLRQPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N0B8</accession>
    <name>A0A1C7N0B8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Putative galactinol--sucrose galactosyltransferase 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">RFS2</name>
        <name evidence="5" type="ORF">A0J61_09390</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Hydrolysis of terminal, non-reducing alpha-D-galactose residues in alpha-D-galactosides, including galactose oligosaccharides, galactomannans and galactolipids.</text>
            <dbReference type="EC" id="3.2.1.22"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>alpha-D-galactosyl-(1-&gt;3)-1D-myo-inositol + sucrose = raffinose + myo-inositol</text>
            <dbReference type="Rhea" id="RHEA:20161"/>
            <dbReference type="ChEBI" id="CHEBI:16634"/>
            <dbReference type="ChEBI" id="CHEBI:17268"/>
            <dbReference type="ChEBI" id="CHEBI:17505"/>
            <dbReference type="ChEBI" id="CHEBI:17992"/>
            <dbReference type="EC" id="2.4.1.82"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the glycosyl hydrolases 36 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000839">
        <property type="protein sequence ID" value="OBZ82560.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N0B8"/>
    <dbReference type="STRING" id="101091.A0A1C7N0B8"/>
    <dbReference type="InParanoid" id="A0A1C7N0B8"/>
    <dbReference type="OrthoDB" id="4664297at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004557">
        <property type="term" value="F:alpha-galactosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047274">
        <property type="term" value="F:galactinol-sucrose galactosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008811">
        <property type="entry name" value="Glycosyl_hydrolases_36"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31268">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31268:SF32">
        <property type="entry name" value="GALACTINOL--SUCROSE GALACTOSYLTRANSFERASE 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05691">
        <property type="entry name" value="Raffinose_syn"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="5" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00049426"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OBZ82560.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="529" mass="61286" checksum="B68E41AF87FA06DA" modified="2016-11-30" version="1">MSQSSILLTPDINASVLINQQGENTADFYCHSSVARQIELWTNLSEDKSWIGIPFTRQNETDYSLKVEIINLKPDNYEYTLRFRRGEDDVDWFWYSNIDDNGKIRIVPSSDKTSILLEGHKHFKAITRLHLDNVYLQHFTLYPKSPLSILLEISHNIYSFLVLLRKGSCWVTPVSGYNTFDSRSDHERWQMVMYEDSKDGCVYLWTIASQSSDCWFSPKGGNSISVCHSSERDDDINLLISSTPFKDDFAKLVSTTISYYQQMTNRSNKSVSQSYFKSVLLEKLGYCTWNAFGKEVSLEKIHTAVESLSKHDIPIGYLIIDDGWQAVNSKSQFDSFDACPKKFPGGLKHMVEELKSFYPFLKAVGVWHTLWGYWNGLDEDFANDNGYWWSGFEKKDSSDFIGILSEPSKFYADFYSFLSSSGVDFVKVDNQGAFQDLNADFNAKIQTWDDYRLSMVNNAYRFLKGQIMHLLFKFRNSDDFFPNEKESHTWHIYANIINALWSSQYPVIGDWDMFQSDHPFAEYHASSLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N0D6</accession>
    <name>A0A1C7N0D6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Putative ATP-dependent permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">ADP1_1</name>
        <name evidence="12" type="ORF">A0J61_09392</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000840">
        <property type="protein sequence ID" value="OBZ82557.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N0D6"/>
    <dbReference type="STRING" id="101091.A0A1C7N0D6"/>
    <dbReference type="InParanoid" id="A0A1C7N0D6"/>
    <dbReference type="OrthoDB" id="66620at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03213">
        <property type="entry name" value="ABCG_EPDR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.25.10">
        <property type="entry name" value="Laminin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013525">
        <property type="entry name" value="ABC2_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050352">
        <property type="entry name" value="ABCG_transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000742">
        <property type="entry name" value="EGF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48041">
        <property type="entry name" value="ABC TRANSPORTER G FAMILY MEMBER 28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48041:SF2">
        <property type="entry name" value="ATP-DEPENDENT PERMEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01061">
        <property type="entry name" value="ABC2_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00022">
        <property type="entry name" value="EGF_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01186">
        <property type="entry name" value="EGF_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50026">
        <property type="entry name" value="EGF_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="8" id="KW-0245">EGF-like domain</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="258"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="668"/>
            <end position="690"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="702"/>
            <end position="723"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="744"/>
            <end position="772"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="784"/>
            <end position="806"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="813"/>
            <end position="831"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="896"/>
            <end position="918"/>
        </location>
    </feature>
    <feature type="domain" description="EGF-like" evidence="10">
        <location>
            <begin position="25"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="11">
        <location>
            <begin position="313"/>
            <end position="553"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="8">
        <location>
            <begin position="48"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="12">
        <location>
            <position position="922"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="OBZ82557.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="922" mass="103624" checksum="B7C257075AA1E4B1" modified="2016-11-30" version="1" fragment="single">MKNNTILFPYRVRKRQECPECPVCFNCQLPSDTCANGGHCDVSGACACPAGWGGLDCTQPLCGSLYQDNREPRRQGEQCKCDPGWGGVNCNVCQQDNVCKTVKGEDAVCLKNAIGLKSMHAWCATTNIPWIDNTHVSLSCEWQKDECIFQFWKDNEEQFYCQLSECTQTTSDTDDVQGHCAKATCGCMKDAFMCGREVGPSEWFCKNGKDCWYNEYSTLVSVFPDNIQLDCNVGECANQQDFLDVGPINREFSSYTELMIVCAIAVACLLLFGITRVTAIRQKKMFSTRIELDEDEDDQDYLLDSAQSTQVSLTFSNISYNVNGKQILSDIHGYLEPGQMMAVMGPSGAGKSSLLDILSRKHKRGIISGNIWINNAQPTKRQFKKITGFVDQDDSLMGTLTVRETLTYAALMRLPRKMPLKVKQKRVEDVMQELGIAKIADSLIGMPGQRGISGGEKRRVSIGKELVTSPSLLFLDEPTSGLDAYNAGVVMECLKKLVRDGKRTIIVTIHQPRSNIFKMFDSLMLLANGRQVYFGPTRSCSDYFKSLGFTLPTDYNIADYLIDLTIKKPEESINRSTTPVSFYQNQNDVEAEPLEEIRPSLDLQGEQHQEESSEFARIEQPSISETESYNIWVDTSGPQTSKLSIFQFYHEMTLLSSRTFINLYRNPFLFFAHFVFAIVLAVLLGCLFWQVDVDLSGVQNRLGVLFFMCALLGFASTSALDMFNKERVLFMRERENGYYSPGAYFVAKVLFDIVPLRVLPPLLMGSISYYMIGLNASFSVFAKFLLVLVLFNLSAAGLCLCFATAFKNISVANLLANLVILFSMLFGGFLLNKDHIPPILSWLQYLSFFNYGFEALIVNELKDITLRDKSIADIQIPGPIILARFGFNGQAFWSDVVRLICFVIVTMSMSFVFLKFLVKEKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N1G4</accession>
    <name>A0A1C7N1G4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_09098</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000773">
        <property type="protein sequence ID" value="OBZ82851.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N1G4"/>
    <dbReference type="STRING" id="101091.A0A1C7N1G4"/>
    <dbReference type="InParanoid" id="A0A1C7N1G4"/>
    <dbReference type="OrthoDB" id="5598843at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="15"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ82851.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="164" mass="17817" checksum="BB396337FBC77BD2" modified="2016-11-30" version="1">MPGNPKKSNERRDSSTYNKQQRKNSSGTKKEAHNTNPNNKPIHNQKAQQAAGAAILSAVISPQSSGLIQSQQPVVGLNGFNRGELVEFLNMHALTAYHDTNLDASVRPEKYESSQKPAQTSAWGSKPAFAWGQSLPHKSNTDTTGVMSNGVDFLTELANRSTIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N1J9</accession>
    <name>A0A1C7N1J9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 7">Origin recognition complex subunit 4</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">orc4</name>
        <name evidence="9" type="ORF">A0J61_08938</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Component of the origin recognition complex (ORC) that binds origins of replication.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the ORC4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000739">
        <property type="protein sequence ID" value="OBZ83015.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N1J9"/>
    <dbReference type="STRING" id="101091.A0A1C7N1J9"/>
    <dbReference type="InParanoid" id="A0A1C7N1J9"/>
    <dbReference type="OrthoDB" id="343623at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005664">
        <property type="term" value="C:nuclear origin of replication recognition complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003688">
        <property type="term" value="F:DNA replication origin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006270">
        <property type="term" value="P:DNA replication initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00009">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:003506">
        <property type="entry name" value="Predicted protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041664">
        <property type="entry name" value="AAA_16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016527">
        <property type="entry name" value="ORC4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032705">
        <property type="entry name" value="ORC4_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12087">
        <property type="entry name" value="ORIGIN RECOGNITION COMPLEX SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12087:SF0">
        <property type="entry name" value="ORIGIN RECOGNITION COMPLEX SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13191">
        <property type="entry name" value="AAA_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14629">
        <property type="entry name" value="ORC4_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF007858">
        <property type="entry name" value="ORC4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0235">DNA replication</keyword>
    <keyword evidence="5 7" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6 7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="8">
        <location>
            <begin position="76"/>
            <end position="232"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005334"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00019083"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRNR" id="PIRNR007858"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OBZ83015.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="444" mass="50726" checksum="A3DC544A207B8457" modified="2016-11-30" version="1">MAKRTIEESEIDTLDDFQPKLAKITDKETDSIDRLLVHRLLLARLNSVELPTQLRGLENEYNTLYTLLRQTVTKGESNSCLLIGNRGTGKTALVRSVIRDLQKIHKDFCIVKLNGLTETSDRLALNEIARQLAIEEQADRTFTSFADSFDYLLSLLKSGSKSSLPVLFILDEFDLFAEHPKQALLYNLFDAAQSAQNPMAVIGLTCRIDTLELLEKRVKSRFSHRQIYLFPSSHFGQFVEICKETLLLPDSYKGSASYNHALDRLFQNPTIHTLLRRIFDISKDVRMFHKICFYPVCRLASVSPYLSVDDFVESSLTQRADSKTELLKGIALLEIVLIISMKKLLERDITTFNFQMVYDEYKEFANHAQIKSQTTGIKLYKKQVALKAFENLQLLELVCPVDMAGKCPKEFRMTKLMMESAQVTEAVLKHNCPDIVKKWGVGMM</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N1X8</accession>
    <name>A0A1C7N1X8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_10587</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001252">
        <property type="protein sequence ID" value="OBZ81364.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N1X8"/>
    <dbReference type="STRING" id="101091.A0A1C7N1X8"/>
    <dbReference type="InParanoid" id="A0A1C7N1X8"/>
    <dbReference type="OrthoDB" id="2287834at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="116"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="118"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="227"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ81364.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="227" mass="26066" checksum="372A2F05C616E031" modified="2016-11-30" version="1" fragment="single">MQELSGHFKSNQQKTKFYLSSKSKIIFLYKKPSIMQLSSSISSTTLEFELVMEALTVKVRLSTSLAYRTPLEHWKKRTCKKIVSMMSGVCVKIVLEYTEAVEEAESSLSLIQMAENDPSTKDGKKFPSERRDAPWPSPKKTKQLIDLLKNHVRDLIYDQVNRSANRAAHCVIRGSYKSGGFIRILKSLWDSSSRTSLKEMFSISSRHHMLLRDQDLRNLNFADCFCT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N2I6</accession>
    <name>A0A1C7N2I6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="16">ADP/ATP translocase</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="16">ADP,ATP carrier protein</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="17" type="primary">ABT_0</name>
        <name evidence="17" type="ORF">A0J61_08634</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">ADP:ATP antiporter that mediates import of ADP into the mitochondrial matrix for ATP synthesis, and export of ATP out to fuel the cell. Cycles between the cytoplasmic-open state (c-state) and the matrix-open state (m-state): operates by the alternating access mechanism with a single substrate-binding site intermittently exposed to either the cytosolic (c-state) or matrix (m-state) side of the inner mitochondrial membrane.</text>
    </comment>
    <comment type="function">
        <text evidence="16">Catalyzes the exchange of ADP and ATP across the membrane.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>ADP(in) + ATP(out) = ADP(out) + ATP(in)</text>
            <dbReference type="Rhea" id="RHEA:34999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="12">
            <dbReference type="Rhea" id="RHEA:35000"/>
        </physiologicalReaction>
    </comment>
    <comment type="subunit">
        <text evidence="3 16">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="16">Membrane</location>
            <topology evidence="16">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 15">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000684">
        <property type="protein sequence ID" value="OBZ83312.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N2I6"/>
    <dbReference type="FunCoup" id="A0A1C7N2I6">
        <property type="interactions" value="291"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N2I6"/>
    <dbReference type="InParanoid" id="A0A1C7N2I6"/>
    <dbReference type="OrthoDB" id="270584at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005471">
        <property type="term" value="F:ATP:ADP antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140021">
        <property type="term" value="P:mitochondrial ADP transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990544">
        <property type="term" value="P:mitochondrial ATP transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.50.40.10:FF:000001">
        <property type="entry name" value="ADP,ATP carrier protein, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002113">
        <property type="entry name" value="ADT_euk_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002067">
        <property type="entry name" value="MCP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45635">
        <property type="entry name" value="ADP,ATP CARRIER PROTEIN 1-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45635:SF14">
        <property type="entry name" value="ADP_ATP TRANSLOCASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00927">
        <property type="entry name" value="ADPTRNSLCASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00926">
        <property type="entry name" value="MITOCARRIER"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0050">Antiport</keyword>
    <keyword evidence="11 14 16" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="8" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0677">Repeat</keyword>
    <keyword evidence="6 14 15" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 16" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4 15" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="109"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="174"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="212"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="14">
        <location>
            <begin position="6"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="14">
        <location>
            <begin position="111"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="14">
        <location>
            <begin position="210"/>
            <end position="296"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022449"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00024143"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00045250"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="RuleBase" id="RU000488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="RuleBase" id="RU368008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="OBZ83312.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="302" mass="33121" checksum="8CA8CCD7AABF145B" modified="2016-11-30" version="1">MATDQNKFVIDFLMGGVSAAVSKTAAAPIERIKLLIQNQDEMIKQGRLSHPYKGIGDCFARTMKDEGAISFWRGNTANVIRYFPTQALNFAFKDKFKRMFNKDKKRDGYWAWFAGNLASGGAAGAASLFFVYSLDYARTRLANDAKSAKKGGERQFNGLVDVYKKTLASDGISGLYRGFNISCVGIIVYRGLYFGLYDSVKPLMPENLQSSFLATFALGWAVTTGSGLASYPIDTVRRRMMMTSGAAVKYDSSLHAFREIVAKEGTKSLFKGAGANILRAIAGAGVLSGYDYLQVLVFGKKY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N2M8</accession>
    <name>A0A1C7N2M8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_08607</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000680">
        <property type="protein sequence ID" value="OBZ83340.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N2M8"/>
    <dbReference type="STRING" id="101091.A0A1C7N2M8"/>
    <dbReference type="InParanoid" id="A0A1C7N2M8"/>
    <dbReference type="OrthoDB" id="2290998at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="40"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="80"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="175"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="508"/>
            <end position="542"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="595"/>
            <end position="679"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="50"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="83"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="175"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="516"/>
            <end position="542"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="596"/>
            <end position="628"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="629"/>
            <end position="644"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="645"/>
            <end position="656"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="663"/>
            <end position="679"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="679"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ83340.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="679" mass="74360" checksum="3045305CFDAEF09B" modified="2016-11-30" version="1" fragment="single">MSHGPSRAYPSHSYSAMSPNAMARQQVMSSSQSFQQIVASSSPNLGDMGSPSSNNNPNVVATGANAVANSPVSTRTISNRLQASNSPTSTASTAPSNSSKSTSGGALSAQDKLYCDSCQTFRSIDIFVKKDRTYNVCRICQNREMQKKKQHAERYEIFEEQQQRNKQQRFIQYTAPPSSQQQQALSPTLLNNNNNASNKSNLNNNNHHTSSNATTGNNTVNSHVFSPLAHSASSSNSGNNTDASSNTPSHIKPPSTTSGSNHTRHNNDKHVYTTINSMPQVQSHLPTQTIQSSISLPMPTQQQEMQQMKNEALIHRLEKSNMMNNAQNSTSPMTSIMPATSVTSTSNALGSSVDRNGTNSITTHHKASAALERASQTVISLEAFVHELERESEFDRKTYHLNIHPLIIRLGSNPGFTQLGRAICEHVLEGTKFNFSLKDRRRSTKSPDTLSTLRYYCSQRADTARPRKTENSKAQTRYDCAGALTIIIDLIKQTAHVTLIHKHQHPPFMSQHHHLQQLQQQLKVSQRQPRQSQSQPQPAVTALSTSATAVPIVSSTTAPLLASLQSTAPASPSLSITASAPTIAHPSLSSITMNHQSQMLPQPQTQSQPQPSLSRLQSQQQQQLSHSPHTISHASSTSKLNNSIQQHSPQQPRQSHTVVQQFPSPQHISHSIQHSVQTQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N2Q8</accession>
    <name>A0A1C7N2Q8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Protein FAR1-RELATED SEQUENCE 11</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">FRS11</name>
        <name evidence="3" type="ORF">A0J61_08651</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000687">
        <property type="protein sequence ID" value="OBZ83301.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N2Q8"/>
    <dbReference type="STRING" id="101091.A0A1C7N2Q8"/>
    <dbReference type="InParanoid" id="A0A1C7N2Q8"/>
    <dbReference type="OrthoDB" id="2277862at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd22744">
        <property type="entry name" value="OTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.70.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018289">
        <property type="entry name" value="MULE_transposase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052579">
        <property type="entry name" value="Zinc_finger_SWIM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31569">
        <property type="entry name" value="SWIM-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31569:SF4">
        <property type="entry name" value="SWIM-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10551">
        <property type="entry name" value="MULE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MULE transposase" evidence="2">
        <location>
            <begin position="279"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="125"/>
            <end position="150"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF10551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ83301.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="932" mass="107184" checksum="C9958BB850E6C730" modified="2016-11-30" version="1">MSSQVSLDNSQLTVTDSQMRRMTTSATVTCDWNDFSDAELLVFDETREESEHEVVSTVVAESSNDMKEEFGKIFFVGAKFRSLDELRDKAQALGKEVNCPITTARSSKNSYIVLRCRHGGAYRKVKKVEPDTEREESSEDTNKSGRHYQSGRKRCPLRIYASHNHALRSDLSTYSVFRKLLPEDFEAACSMMKKGETPRSVLKLLVEKQVDNGITLSDLHNVQQRFCNDQFSGMPEFISDLEQTGHQVRTRVDSDDKVNAVFFMHEHGRDELRRLPESVIIDATYKTDSHRMVLLNIVVAGTVASEYRRSQLVTIHVAGCWMRKETTESYEWAMKQLRSIAWPSGTDPSLLPDNFVTDKDQTLMNAIKVVFPESKQILCYVHIVHNFMKRLIKSMSKKVQLDKESHPLLEKRFIAIVHKIAFQSNTKEALIGFKNEYDAFVSQDNLCVDKGKEMKTYLDSMMAFRRHWVGYYVNTYVLMGNRTSNRVESTHSGIKRHNKTSSGLLGLVTKKIREWVEGRESYRNRQTVRESLFETILKDKTGHEIDDKMSQLRGRITSFAFDRIRFEYINLMDNKADPDHVSHVESTMGKCLCKLRRAYRLPCRHRIARYNGPIPLSAVHRRWHIMYQNGRVATIAEMTNASKEHNPEEHEVRKPVEVQLQKLQYIDADLKTQGERISLEDELRVIISKYSDDKKVERILPPPIVYDIKGRPKNTTREKIALEREMDKIAQLAKQEKASQKEVAQVRLAIPIPKGLSAKQVTGHFNPSPDGNCGYRAIAHAVFDDEANFGNVKHEMLLCLRKNEQFYRQVFGSSPSASEVLSGTFESIQSKLSNDTSAGITDNWFQFPEMVQLAADAFSRAIACYTPDNQSTTFAPYYSPPFPVHPILLQLYNSHFYIVELKPNSKPRWPRTYPGHPFNCKRHSLEDFSLIY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N2S0</accession>
    <name>A0A1C7N2S0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Tetratricopeptide repeat protein 39B</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">ttc39b_1</name>
        <name evidence="1" type="ORF">A0J61_08632</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000683">
        <property type="protein sequence ID" value="OBZ83321.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N2S0"/>
    <dbReference type="InParanoid" id="A0A1C7N2S0"/>
    <dbReference type="OrthoDB" id="43460at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005741">
        <property type="term" value="C:mitochondrial outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019412">
        <property type="entry name" value="IML2/TPR_39"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31859">
        <property type="entry name" value="TETRATRICOPEPTIDE REPEAT PROTEIN 39 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31859:SF1">
        <property type="entry name" value="TETRATRICOPEPTIDE REPEAT PROTEIN 39C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10300">
        <property type="entry name" value="Iml2-TPR_39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ83321.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="579" mass="66778" checksum="6016B7C936D324C7" modified="2016-11-30" version="1" fragment="single">AFVLFLKSMMTFEKEDIAEAIDALKLTIQLADALRKKETGWFGNITSWVKGMSVQDVCSMSRLHRHAELVYAESYLLKALLCIVYDESLVSFLREGLHVRSSYNTYRVLHKFLSQVQDEAMQGKDVSAYNLDDHFTSGVSLGIGLFNIMISLLPTSVVKVVEFVGFTSDRQEGMNILESVGGWEEYAGLALSELPPLQGADEGLRRQFCDMVLMMYHIIMPKLIPLSDINEELADRVLAYNLKLYPDGVFFLYFSGRQLSTRGLLDQAKQQYQKAIDMQKDWKQLQHMCYWELGLIHSLQQNWQGSQLCYTKLQQESNWSKAVYYYLQAVSLYMLSLEEKDSKEQSRLLKQAHIMMQKVTGAKQKIAGKSIPVEKFVSRKARKFIAQNDSLLFPDLEALNAFSAFEFMSQDLLKSNLERITKEIDRLTTKTAHTEVLNYYDDLCLCHYLRTMILRLLLSRYSDESSQQKQAWKNLHAESIQSVMDNADKIQLDHYIYYFSRYEEARMCIYDQDYQKAKDIIQFIIKISEKGQFNVGAGPHAKNKYSLENNILFKCHNCFAEIETLSVAEDSSSSLAKKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N2X2</accession>
    <name>A0A1C7N2X2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Importin-13</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">Ipo13</name>
        <name evidence="10" type="ORF">A0J61_08500</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="3">Interacts with UBC9, RAN, RBM8A, eIF-1A and PAX6.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the importin beta family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000661">
        <property type="protein sequence ID" value="OBZ83452.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N2X2"/>
    <dbReference type="FunCoup" id="A0A1C7N2X2">
        <property type="interactions" value="225"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N2X2"/>
    <dbReference type="InParanoid" id="A0A1C7N2X2"/>
    <dbReference type="OrthoDB" id="2016913at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031267">
        <property type="term" value="F:small GTPase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006606">
        <property type="term" value="P:protein import into nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013598">
        <property type="entry name" value="Exportin-1/Importin-b-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001494">
        <property type="entry name" value="Importin-beta_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051345">
        <property type="entry name" value="Importin_beta-like_NTR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040709">
        <property type="entry name" value="Importin_rep_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040520">
        <property type="entry name" value="Importin_rep_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057942">
        <property type="entry name" value="TPR_TNPO3_IPO13_3rd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12363:SF33">
        <property type="entry name" value="IMPORTIN-13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12363">
        <property type="entry name" value="TRANSPORTIN 3 AND IMPORTIN 13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03810">
        <property type="entry name" value="IBN_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18773">
        <property type="entry name" value="Importin_rep"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18806">
        <property type="entry name" value="Importin_rep_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24140">
        <property type="entry name" value="TPR_TNPO3_IPO13_3rd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08389">
        <property type="entry name" value="Xpo1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00913">
        <property type="entry name" value="IBN_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50166">
        <property type="entry name" value="IMPORTIN_B_NT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-0653">Protein transport</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Importin N-terminal" evidence="9">
        <location>
            <begin position="28"/>
            <end position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011422"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00016020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50166"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OBZ83452.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="982" mass="111324" checksum="93CB922A3717604F" modified="2016-11-30" version="1">MEIQSIAQVEGLIQQLYSLSDPLVTKQIQDQLQILQKQPFAWEIASQLLSSQSDQCRFFGALTFQVKITRDWETLSENRRMWLKDELLGWIVRLCGGPAFVVTKLCLALIAYAFHTVPDEWPNFITSTIDAFQMGSQAYQIPPDTLHYLILEFLTLVPEEVQNANLIGGRKLQLIGQLKEGIPLALSTISALLFSVEIQPVVQQKAMRCLQSWIQYGFDLEKGYPILQQVMSLLGNEDVFEQATEVLLESMQQSNWAKYQTYRNDLLTCFTSQGMREKFETSIAEEDEETARLLAKLFSTFGETYTDFIVMQLARPDVEWLMHMIMQLTGFQGYFPVDQEVSEIPLNFWYIMQETLFDENILPIREPTAADQEDAEKKVWMIKCGQTAIAIYKQLVKVLIQNARYPDDSTWNSWNKDVKDKFKIWRRDLGDTMINPYYVLRDEMLQILLDHIAYIINQWASLPDASQLLEATLFCLKSITEEISPEENVYIQQLFGLDILGRFPNNCSARLTNTSLLLMGSLADWLKVHPQFLGPVMNYIVPCLSDRSLALAASSAFSDICDNCRESLVNELDNLMHVYAAMSKSQIKVNFMQKVVESVADVIQVLPPDRAMAPLMTLAGDILQGISSALKSVDTDPQAAHDAVLVQLQYLTACCRGIQSPNDDYQSLIQRNSSYDTFAAGHSAALYAHIEGFQEITFAIRELTAQITQVWSSDEAIVKALSTFLEQGMRSTSPLLSLSFHDLVVLIEKSYSTAPYACWLNTASMMMTVYGGQEHNKERLRDLLGSVTNKTTEFINGTEAMEQYPDVVDNYFGLLSRAITRCPFSFYRLPTSMIDTIFMFVIAGMGQQERLALKAALNFMSDFISQDYQENSEIAQVMDGIMNNMGIRIMEQLLLGIGGRVPRSFASPLVDLLFKLIGKYLQLCRQWMQSLLANDGFPSSLATPSDKEAFMKGVLSTRSPKRFKEHTNTFSIKCRGLGNTSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N2Y0</accession>
    <name>A0A1C7N2Y0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="19">Peroxisomal hydratase-dehydrogenase-epimerase</fullName>
            <ecNumber evidence="5">1.1.1.n12</ecNumber>
            <ecNumber evidence="6">4.2.1.119</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="20">Multifunctional beta-oxidation protein</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="23" type="primary">fox-2</name>
        <name evidence="23" type="ORF">A0J61_08488</name>
    </gene>
    <organism evidence="23 24">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="23 24" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="23 24">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="18">Second trifunctional enzyme acting on the beta-oxidation pathway for fatty acids, possessing hydratase-dehydrogenase-epimerase activities. Converts trans-2-enoyl-CoA via D-3-hydroxyacyl-CoA to 3-ketoacyl-CoA.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="17">
            <text>a (3R)-3-hydroxyacyl-CoA + NAD(+) = a 3-oxoacyl-CoA + NADH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:32711"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57319"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:90726"/>
            <dbReference type="EC" id="1.1.1.n12"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="16">
            <text>a (3R)-3-hydroxyacyl-CoA = a (2E)-enoyl-CoA + H2O</text>
            <dbReference type="Rhea" id="RHEA:26526"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:57319"/>
            <dbReference type="ChEBI" id="CHEBI:58856"/>
            <dbReference type="EC" id="4.2.1.119"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Lipid metabolism; fatty acid beta-oxidation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Peroxisome</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="23">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.n12" evidence="5"/>
    <dbReference type="EC" id="4.2.1.119" evidence="6"/>
    <dbReference type="EMBL" id="LUGH01000659">
        <property type="protein sequence ID" value="OBZ83462.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N2Y0"/>
    <dbReference type="STRING" id="101091.A0A1C7N2Y0"/>
    <dbReference type="InParanoid" id="A0A1C7N2Y0"/>
    <dbReference type="OrthoDB" id="3592703at2759"/>
    <dbReference type="UniPathway" id="UPA00659"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005777">
        <property type="term" value="C:peroxisome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018812">
        <property type="term" value="F:3-hydroxyacyl-CoA dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016853">
        <property type="term" value="F:isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006635">
        <property type="term" value="P:fatty acid beta-oxidation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd03448">
        <property type="entry name" value="HDE_HSD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd05353">
        <property type="entry name" value="hydroxyacyl-CoA-like_DH_SDR_c-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000410">
        <property type="entry name" value="Peroxisomal multifunctional beta-oxidation protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.129.10:FF:000013">
        <property type="entry name" value="Peroxisomal multifunctional enzyme type 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000185">
        <property type="entry name" value="peroxisomal multifunctional enzyme type 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.4290">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.129.10">
        <property type="entry name" value="Hotdog Thioesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029069">
        <property type="entry name" value="HotDog_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057326">
        <property type="entry name" value="KR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002539">
        <property type="entry name" value="MaoC-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054357">
        <property type="entry name" value="MFE-2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051687">
        <property type="entry name" value="Peroxisomal_Beta-Oxidation"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45024">
        <property type="entry name" value="DEHYDROGENASES, SHORT CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45024:SF2">
        <property type="entry name" value="SCP2 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01575">
        <property type="entry name" value="MaoC_dehydratas"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22622">
        <property type="entry name" value="MFE-2_hydrat-2_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SMART" id="SM00822">
        <property type="entry name" value="PKS_KR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54637">
        <property type="entry name" value="Thioesterase/thiol ester dehydrase-isomerase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="13" id="KW-0413">Isomerase</keyword>
    <keyword evidence="11" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="14" id="KW-0456">Lyase</keyword>
    <keyword evidence="15" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="9" id="KW-0521">NADP</keyword>
    <keyword evidence="10" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12" id="KW-0576">Peroxisome</keyword>
    <keyword evidence="24" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Ketoreductase" evidence="22">
        <location>
            <begin position="10"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="21">
        <location>
            <begin position="878"/>
            <end position="898"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004275"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005005"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012456"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00013156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00029334"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00052025"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00055743"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00073871"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="ARBA" id="ARBA00081853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="21">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="22">
        <source>
            <dbReference type="SMART" id="SM00822"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="EMBL" id="OBZ83462.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="24">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="1024" mass="109633" checksum="FD3E84BA6940A8B7" modified="2016-11-30" version="1">MTKEIRFDGKVVIVTGAGGGLGKAYALFFAKRGANIVVNDLGVSHTGDGSSSKAADVVVEEIQKLGGKAVANYNSVTDGDKIVETAMKAFGRVDIVINNAGILRDKSFARMTDADWDLIHAVHVKGSYAVTKAAWPIMRKQKYGRIIMTASAAGLYGNFGQANYSAAKLALASFSNSLAKEGAKDNIHCNTIAPMAASRMTETVLPPEVLASLKPEFVTPVVGYLCHEDTEDNGGVFEVGGGQVFKLRWERSAGAVFKADDSFTPAAVGAKWNEVTDFEKANEYPTSVMDTDFVALLERAKQAEANPKAEPLRFDGQVAIVTGAGGGLGKAYALLLAKLGASVVVNDLGGSATGQGADSRAADLVVEEIRKAGGKAVANYDSVEEGDKVVETALKAFGRIDIIVNNAGILRDKSFARMTDADWDLVHRVHLRGTYKVLKAAWPHFVKQKYGRIINTASAVGLYGNFGQTNYSAAKLGVVGLTRTLALEGQSKNIIANVIAPNAGTRMTATVMPPEMVEAFKPEYVAPLVAYLGHSSNEETGGIFEVLKAAWPHFVKQKYGRIINTASAVGLYGNFGQTNYSAAKLGVVGLTRTLALEGQSKNIIANVIAPNAGTRMTATVMPPEMVEAFKPEYVAPLVAYLGHSSNEETGGIFEVGSGWVAQVRWQRTGGVGFPANRELTPEQVAQAWNKIVDFEDGRASNPNSTQDSFQGFMENFANVADEENANKGNEGAVDVEAGKKLDLDVLEFSYGEREAILYALGLGCKRTDTRFVYENDMNFGVLPTFGVVPSLKAMEAVPFGDFLPNFNPMMLLHGEQFLSLKKPIPVSGTLKSKARVIEVLDKGKGASVVVSVITTDESGEAVFENEFTLFVRGSGGFGGKSKGEDRGAASATNAVPNRKPDAVVTEKTNEDQAALYRLSGDYNPLHIDPEMSAIGGFDVPILHGLCSFGISAKHVLKTFGKNDPETFSNIKARFAKHVFPGETLETSMWKEGNKVIFQTRVVERDVIAISNAAVELKASRESKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N2Y8</accession>
    <name>A0A1C7N2Y8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Elongation factor 3</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12">Eukaryotic elongation factor 3</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="15" type="primary">tef3_2</name>
        <name evidence="15" type="ORF">A0J61_08527</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Protein biosynthesis; polypeptide chain elongation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the ABC transporter superfamily. ABCF family. EF3 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000666">
        <property type="protein sequence ID" value="OBZ83421.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N2Y8"/>
    <dbReference type="STRING" id="101091.A0A1C7N2Y8"/>
    <dbReference type="InParanoid" id="A0A1C7N2Y8"/>
    <dbReference type="OrthoDB" id="2110130at2759"/>
    <dbReference type="UniPathway" id="UPA00345"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd03221">
        <property type="entry name" value="ABCF_EF-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.10.10:FF:000076">
        <property type="entry name" value="Elongation factor 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000193">
        <property type="entry name" value="Probable Elongation factor 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050611">
        <property type="entry name" value="ABCF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021133">
        <property type="entry name" value="HEAT_type_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034085">
        <property type="entry name" value="TOG"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19211">
        <property type="entry name" value="ATP-BINDING TRANSPORT PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19211:SF5">
        <property type="entry name" value="ELONGATION FACTOR 3A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24984">
        <property type="entry name" value="HEAT_EF3_GNC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24987">
        <property type="entry name" value="HEAT_EF3_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01349">
        <property type="entry name" value="TOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50077">
        <property type="entry name" value="HEAT_REPEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7 15" id="KW-0251">Elongation factor</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="HEAT" evidence="13">
        <location>
            <begin position="190"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="14">
        <location>
            <begin position="439"/>
            <end position="658"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="15">
        <location>
            <position position="751"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004815"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022768"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00049360"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00050030"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00050045"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="OBZ83421.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="751" mass="82402" checksum="AC35F72A02D524A2" modified="2016-11-30" version="1" fragment="single">MPAAAAAKQSEIQSKKLTIVSPSEVENKKAKEIVTKLAAASDADREAVAAELAAHIKANGILALKPVLEQLKKDIAHKKNAGTRAGAVAAIVALTNENVEHQTEPYIAPFLVNLLELQADKQTSVKDAAEKAAKNLCEKINANACSLLVPYILEGLGNSCKWQTKMLSLELLETLTKTFKTDFVVAIPDVVPVVSDCMWDTKADVKKKATETMGVICSLVNNKDIERFIPAVINCINHPENVPETIHLLGATTFVQEVDSATLSIMVPLLNRGLNERATPIKRKSALIIDNMSKLVDDPDVAAPFLPVLLPALEHVQDIVADPECRGVVQKALATLQRLKNPGTEVFTKDQKKIKVDSSIKELLPENMDEFLNTTVAFMNDVALSLCVSKNFFKNVWIKTLAPYAKTFVSAEDAESLAVTALNKCEEAVTPKDPEEEDDEGEDLCNCEFSLAYGAKILLNRTALRLKRGRRYGLCGANGCGKSTLMRAIANEQVEGFPPRSELKTVYVEHDIDGSEADTPLVDFILASEGVETKDPEQVRKILLDYGFSEAMVTKMAIGELSGGWKMKLALARAMLMNADILLLDEPTNHLDVVNVAWLENYLLGLKTVTSIIVSHDSGFLDHVCSDIIHYEPNYKLKRYKGNLSEFVKKVPRAASYYSLEASQISFKFPEPGFLEGIKTKERAILKMKNVDFQYPGSDRKQLIDISMQCSLSSRVAVIGPNGAGKSTLIKLLTGEIESEVGSVWKHPNLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N3J8</accession>
    <name>A0A1C7N3J8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Protein EFR3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">EFR3_1</name>
        <name evidence="2" type="ORF">A0J61_08383</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the EFR3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000639">
        <property type="protein sequence ID" value="OBZ83568.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N3J8"/>
    <dbReference type="FunCoup" id="A0A1C7N3J8">
        <property type="interactions" value="1"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N3J8"/>
    <dbReference type="InParanoid" id="A0A1C7N3J8"/>
    <dbReference type="OrthoDB" id="19232at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072659">
        <property type="term" value="P:protein localization to plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039786">
        <property type="entry name" value="EFR3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049150">
        <property type="entry name" value="EFR3_HEAT-like_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47766">
        <property type="entry name" value="PROTEIN EFR3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47766:SF1">
        <property type="entry name" value="PROTEIN EFR3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21072">
        <property type="entry name" value="EFR3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010216"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ83568.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="911" mass="103019" checksum="7B2D1F2EA855934A" modified="2016-11-30" version="1">MFSNSYTKHATLINNCYPEKEGEKGPRSSELSYLVFYASSRPVKLTKVGLFLEKKVERDVAKGRKQNNQVSLEILKSLVEACHRDLNLFSKYVVKIIDMILETRDIEVVDLACQVFIMFTSYHDGSTLGVDAEFTRDYEELLKKMAVFCAFENQDETLRLQMRYIGQRALQAAVTSTAFQASNFKAQLDLILTPLIITLSNSKCPADTLAQNEDIDIRQSAIDHETSNAHTVEILAAKTSVILFSKINGVAVKLALGPLFEFMDTYEKWWPNTFAVAMMKLALESLQPQYRYLLVSEVLQQLETVKSSMDEKMLEKHASLVSILKAVLNADIPLVGISVLEVLNSLFIHLMKSVQDFKTFQEQQDTMAYAIQQGLCHSIGGLATQTYYLNQLNDITGYLIAKLKVGNTMATQDSLPMKVYRHVVLRCLDLVVSSCTDEPTENELDHAVTVYSNSVTLDIWTPALGLLTDQASETRVDFASILIHYLELTSENEVVLEPYPKHMLNQHSDVVFVNTLHQSIVDWIQLSNLSKNDVLAIRDILSALIRKFGADETIKAVPLMFKIQDLVEQETVALSGSERAVAVAALLVEWLWIIAQKYHIDSLIDYADTIKQKRIQSNQYPTFFLEQERSFDPLDTAESTLMDTWVDRKDVIRMLSKDGPLRDEDDVEGTELESKLMLDWGTETQEKLDRTFRIRTSRNLSDLKAKLATPWTRLDINRDEQDKKQTIGVENLKDALLGQQTEIHVNKNVTNHTQDMTLLLQSLSLDTRLTKNCTLYHTVDHVFAERTQRQLVVSDIWNCLPGIEGINSTMVAYRNESEVVFHNNKENDINSFLENFFDANGAFLVYKTSCCGQKNMLTSAQITFVQHILEDIKASAVDILKNASPAAIPTMNLITSGVLSTANQIKNCLTN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N3W6</accession>
    <name>A0A1C7N3W6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Mitosis inhibitor nif1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">nif1</name>
        <name evidence="1" type="ORF">A0J61_08259</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000620">
        <property type="protein sequence ID" value="OBZ83688.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N3W6"/>
    <dbReference type="STRING" id="101091.A0A1C7N3W6"/>
    <dbReference type="InParanoid" id="A0A1C7N3W6"/>
    <dbReference type="OrthoDB" id="2148946at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032153">
        <property type="term" value="C:cell division site"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010972">
        <property type="term" value="P:negative regulation of G2/M transition of mitotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052945">
        <property type="entry name" value="Mitotic_Regulator"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006597">
        <property type="entry name" value="Sel1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43628">
        <property type="entry name" value="ACTIVATOR OF C KINASE PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43628:SF1">
        <property type="entry name" value="CHITIN SYNTHASE REGULATORY FACTOR 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08238">
        <property type="entry name" value="Sel1"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00671">
        <property type="entry name" value="SEL1"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81901">
        <property type="entry name" value="HCP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ83688.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="265" mass="30201" checksum="668E65A680BCAEDB" modified="2016-11-30" version="1">MNKLKKVFLLNQDNPQKQHRFSSLFPAKQQSDPQLSCTNDRPLDLYRPRSIQPSLITMKSSSSLPSEEVDKSQNEAYLQMGLKYHENGQLEKATYYWRLCAENGYPLGLFFYGIALRHGWGCKKNPMQAVQYLQTAAEFAVYDLQTTAATYNVAKSELVLAIHELGVCFRHGWGVPKNLETAAYYFQVASHLGDPDAQNDLGFCYLHGLGVKKDVFLAAKYYRMAEKQGQGIIGNSWIWKAKYDQVEEPGWAPKTDKKKDQKKKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N446</accession>
    <name>A0A1C7N446_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_08035</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000584">
        <property type="protein sequence ID" value="OBZ83915.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N446"/>
    <dbReference type="InParanoid" id="A0A1C7N446"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ83915.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="136" mass="15354" checksum="BBC06263A085FCCB" modified="2016-11-30" version="1">MGTSSLGFINDCPFVYTLKTSISSPTIAYAQLVPSCTLTAYKVILFVQLLGFNDTVLGNWCQIKPFYRYFASRIITELTLSYSLVLDKDINENAIAALSDRSQPQVFENHERRNHMLQTDFASTFLSIDFSEEAFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N490</accession>
    <name>A0A1C7N490_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_08110</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000595">
        <property type="protein sequence ID" value="OBZ83847.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N490"/>
    <dbReference type="InParanoid" id="A0A1C7N490"/>
    <dbReference type="OrthoDB" id="2284791at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ83847.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="221" mass="25563" checksum="4CE525DCF02CBF98" modified="2016-11-30" version="1">MFRIRNKTVQKEGYYAMFEYNKRIFKQVFHILKDYGIVNSHMMLNRGQVRTPARHFDSWSNLTIESKLDEQEEANLRELCQNFIRRAETSFPAARTHVLLKRAELEGEPESSLEPKAYELLDTINTIIKQKKTEDNMQEADYVDWIKRLLQIVFRSSLLKVTIEKTVTAATKLVVEYNQSTYTGSISSVFASSSFPLASSSTRKSNYSGRKIGLKVTDDNN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N5C9</accession>
    <name>A0A1C7N5C9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Quinidine resistance protein 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">QDR2_1</name>
        <name evidence="8" type="ORF">A0J61_07736</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000540">
        <property type="protein sequence ID" value="OBZ84217.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N5C9"/>
    <dbReference type="STRING" id="101091.A0A1C7N5C9"/>
    <dbReference type="InParanoid" id="A0A1C7N5C9"/>
    <dbReference type="OrthoDB" id="440553at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502:SF51">
        <property type="entry name" value="QUINIDINE RESISTANCE PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="22"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="96"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="138"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="223"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="284"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="1"/>
            <end position="309"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OBZ84217.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="333" mass="37202" checksum="026FE93F34A9A32C" modified="2016-11-30" version="1">MSGPLIGPLVGGIISHSLGWRWIFWITLIIGGTSIFSVTLFVPETLRALVGNGSGYANPTPFQFVARRQGKLDEKKIQAIKETQGPRPRMNFFSPFLYLMEPDVFVMLMFSAFIYMSMYSFMTSTTKQLSMRYGLSELEIGFCYLCMGSGTIIGGLIKGKMLDKDFRKVNEEACLKNPDQKEVEICFYKARLSSCWVSLFFSDVLPIVYGWCLQKNTHLAIPLILQFLTGVSNASLTICIQSLLIDLFPGKGASITASNNLTRCILGAIASSVIDPGIEGVGVGWMFTIIGLLVTLLNISIPVLLKFGPRWRAQRIERLKQNNGQLTFRFFKH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N5E7</accession>
    <name>A0A1C7N5E7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_09384</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000838">
        <property type="protein sequence ID" value="OBZ82564.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N5E7"/>
    <dbReference type="STRING" id="101091.A0A1C7N5E7"/>
    <dbReference type="InParanoid" id="A0A1C7N5E7"/>
    <dbReference type="OrthoDB" id="2289482at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008889488" evidence="2">
        <location>
            <begin position="20"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="171"/>
            <end position="202"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ82564.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="300" mass="31791" checksum="FC14B9050632EC19" modified="2016-11-30" version="1">MKLALSTVLALSLFQLSFAEPDYSVMRVVVRPPNDEENYHVCIETPGCHGEYCVSLRAPGRLIKLFDEERCERILPYYSRENHEDLAYLYMPRFSGIANCHFVEDVDNGRAFDCDIPIDTTTTTTATAATTATTDATTTTTATTDATTDATTDATTATTATTATTATTATTDATNTNDNTGTTSTVTTTTSTTTADSDSDATTTTKKATTFTKKTTTSTKKATTTKKATTSTKKTTKKATTSTKKNTTSTKKATTTKKAIKTASACKAGYLGKKGGNGPKGACCSSTKDCKKACSNKTCT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N5H2</accession>
    <name>A0A1C7N5H2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">SH3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">A0J61_07573</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000518">
        <property type="protein sequence ID" value="OBZ84373.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N5H2"/>
    <dbReference type="STRING" id="101091.A0A1C7N5H2"/>
    <dbReference type="InParanoid" id="A0A1C7N5H2"/>
    <dbReference type="OrthoDB" id="1716625at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00052">
        <property type="entry name" value="EH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.40">
        <property type="entry name" value="SH3 Domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000261">
        <property type="entry name" value="EH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036028">
        <property type="entry name" value="SH3-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001452">
        <property type="entry name" value="SH3_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12763">
        <property type="entry name" value="EH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00018">
        <property type="entry name" value="SH3_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00452">
        <property type="entry name" value="SH3DOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00027">
        <property type="entry name" value="EH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00326">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50044">
        <property type="entry name" value="SH3-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50002">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0728">SH3 domain</keyword>
    <feature type="domain" description="SH3" evidence="4">
        <location>
            <begin position="1"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="5">
        <location>
            <begin position="475"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="92"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="188"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="279"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="129"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="190"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="292"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="317"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="349"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="366"/>
            <end position="384"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OBZ84373.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="520" mass="57128" checksum="9E65077179FD97B2" modified="2016-11-30" version="1">MRMKAVYDCSADESGELSFKEGDILVDVVDSGEEGWYKGRILNTSSVGLFPYNYVVQVPDEPVPKEAPLDAFEAAMMKRKPGASAKALTLEKAKSQPTHMASPTRLRSHSASSVLAKSVFQELDKKNSTPRQHSALRGSSDTSVHTKEEVEEDEEEGYHMVKPSQLKQALNTDLVWLQKTKKAQKDFLNNMPNTTKSSQLTANSSSNPMPRLPSRPVSAAVLKSRQNRNAKPKEITPKPKLQPVLPPRPSKPSTSSNAPPPIHPKPAMSSIEILLNRNNNSNKQKPMPEEPLSSSSVTMGPTPTSSKSMRPKKPDSNSKPNLVTRTDNWASNHTDDANIKPSALFNRARSATNPNTSSTHAFDWESNSTKSLSLSSSNSPSVSNTILPPPPPASRTIPVQDRLPTPIAQEATKTTTDTKKRANPPPPPPSRPSSKSAQRRLTPAEKRYESLFQTVQDQGLLDGETVHCIWIKSKLSNEDLARIWRECDPNHKGVLDKQAFLDGMTKIDECLATKQAMASQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N5L9</accession>
    <name>A0A1C7N5L9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_07504</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000509">
        <property type="protein sequence ID" value="OBZ84445.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N5L9"/>
    <dbReference type="InParanoid" id="A0A1C7N5L9"/>
    <dbReference type="OrthoDB" id="2286358at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ84445.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="261" mass="29269" checksum="D9C8708E9059E8A9" modified="2016-11-30" version="1">MQTSDNLATTHTITSKVIWGFMLENTLFTEFEERNHAIIEAAYKQRKRKQGSHYIHIVDANLPKPGKAKVYFGVVQNHLRMPGTRYYVNRRVVKDRKIPNSPAFVPISSTSTVSSVSDACLSQLDPQLMALFSEDLSLLSPNQSSSASTSSFQLTPDGGLSLSNYFMNAYPIEDHLQGLNHHISNPMSDPYGSYHTQFVGTGLLTDSNQTSKSSNDLNHYPNLQEDTVPWSSIIASDYFTFSSYHPNVFYTTIPTESFSFC</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N6F5</accession>
    <name>A0A1C7N6F5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="20">Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial</fullName>
            <ecNumber evidence="20">1.3.5.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="23" type="primary">sdh1</name>
        <name evidence="23" type="ORF">A0J61_07214</name>
    </gene>
    <organism evidence="23 24">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="23 24" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="23 24">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="15 20">Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14 20">
            <text>a quinone + succinate = fumarate + a quinol</text>
            <dbReference type="Rhea" id="RHEA:40523"/>
            <dbReference type="ChEBI" id="CHEBI:24646"/>
            <dbReference type="ChEBI" id="CHEBI:29806"/>
            <dbReference type="ChEBI" id="CHEBI:30031"/>
            <dbReference type="ChEBI" id="CHEBI:132124"/>
            <dbReference type="EC" id="1.3.5.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="18">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
        <text evidence="18">Flavinylated by SdhE, about 5% flavinylation occurs in the absence of SdhE.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 20">Carbohydrate metabolism; tricarboxylic acid cycle; fumarate from succinate (eukaryal route): step 1/1.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 20">Mitochondrion inner membrane</location>
            <topology evidence="1 20">Peripheral membrane protein</topology>
            <orientation evidence="1 20">Matrix side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 20">Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="23">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.3.5.1" evidence="20"/>
    <dbReference type="EMBL" id="LUGH01000476">
        <property type="protein sequence ID" value="OBZ84735.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N6F5"/>
    <dbReference type="SMR" id="A0A1C7N6F5"/>
    <dbReference type="FunCoup" id="A0A1C7N6F5">
        <property type="interactions" value="255"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N6F5"/>
    <dbReference type="InParanoid" id="A0A1C7N6F5"/>
    <dbReference type="OrthoDB" id="71672at2759"/>
    <dbReference type="UniPathway" id="UPA00223">
        <property type="reaction ID" value="UER01006"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045273">
        <property type="term" value="C:respiratory chain complex II (succinate dehydrogenase)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008177">
        <property type="term" value="F:succinate dehydrogenase (quinone) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006121">
        <property type="term" value="P:mitochondrial electron transport, succinate to ubiquinone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.700.10:FF:000001">
        <property type="entry name" value="Mitochondrial succinate dehydrogenase flavoprotein subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="4.10.80.40:FF:000002">
        <property type="entry name" value="Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.50.50.60:FF:000482">
        <property type="entry name" value="Succinate dehydrogenase complex, subunit A, flavoprotein (Fp)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.58.100:FF:000001">
        <property type="entry name" value="Succinate dehydrogenase flavoprotein subunit (SdhA)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.100">
        <property type="entry name" value="Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.80.40">
        <property type="entry name" value="succinate dehydrogenase protein domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.700.10">
        <property type="entry name" value="Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003953">
        <property type="entry name" value="FAD-dep_OxRdtase_2_FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003952">
        <property type="entry name" value="FRD_SDH_FAD_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037099">
        <property type="entry name" value="Fum_R/Succ_DH_flav-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015939">
        <property type="entry name" value="Fum_Rdtase/Succ_DH_flav-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030664">
        <property type="entry name" value="SdhA/FrdA/AprA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027477">
        <property type="entry name" value="Succ_DH/fumarate_Rdtase_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011281">
        <property type="entry name" value="Succ_DH_flav_su_fwd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014006">
        <property type="entry name" value="Succ_Dhase_FrdA_Gneg"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01816">
        <property type="entry name" value="sdhA_forward"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01812">
        <property type="entry name" value="sdhA_frdA_Gneg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11632">
        <property type="entry name" value="SUCCINATE DEHYDROGENASE 2 FLAVOPROTEIN SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11632:SF51">
        <property type="entry name" value="SUCCINATE DEHYDROGENASE [UBIQUINONE] FLAVOPROTEIN SUBUNIT, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00890">
        <property type="entry name" value="FAD_binding_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02910">
        <property type="entry name" value="Succ_DH_flav_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000171">
        <property type="entry name" value="SDHA_APRA_LASPO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00411">
        <property type="entry name" value="PNDRDTASEI"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46977">
        <property type="entry name" value="Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56425">
        <property type="entry name" value="Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00504">
        <property type="entry name" value="FRD_SDH_FAD_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 20" id="KW-0249">Electron transport</keyword>
    <keyword evidence="8 18 20" id="KW-0274">FAD</keyword>
    <keyword evidence="6 18 20" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="13 20" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="7" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="11 20" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="24" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9 20" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="4 20" id="KW-0813">Transport</keyword>
    <keyword evidence="5 20" id="KW-0816">Tricarboxylic acid cycle</keyword>
    <keyword evidence="23" id="KW-0830">Ubiquinone</keyword>
    <feature type="domain" description="FAD-dependent oxidoreductase 2 FAD-binding" evidence="21">
        <location>
            <begin position="72"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="domain" description="Fumarate reductase/succinate dehydrogenase flavoprotein-like C-terminal" evidence="22">
        <location>
            <begin position="522"/>
            <end position="657"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="16">
        <location>
            <position position="349"/>
        </location>
    </feature>
    <feature type="binding site" evidence="18">
        <location>
            <begin position="77"/>
            <end position="82"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="18">
        <location>
            <begin position="100"/>
            <end position="115"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="18">
        <location>
            <position position="284"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="305"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="317"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="416"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="18">
        <location>
            <position position="450"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="461"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="18">
        <location>
            <begin position="466"/>
            <end position="467"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="modified residue" description="Tele-8alpha-FAD histidine" evidence="19">
        <location>
            <position position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004788"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00049220"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00059077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PIRSR" id="PIRSR000171-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="PIRSR" id="PIRSR611281-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="PIRSR" id="PIRSR611281-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="PIRSR" id="PIRSR611281-4"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="RuleBase" id="RU362051"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="21">
        <source>
            <dbReference type="Pfam" id="PF00890"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="22">
        <source>
            <dbReference type="Pfam" id="PF02910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="EMBL" id="OBZ84735.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="24">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="657" mass="71701" checksum="46C3DF3F9A2D40B7" modified="2016-11-30" version="1">MLKFLQSSSNKALRTTRNLLNLCLDSNAGRMTSRGFHHAKPAMQVMANNPLRAKEANGPIASQYPVIDHEYDAVVVGAGGAGLRAAFGLAEAGLNTACITKLFPTRSHTVAAQGGINAALGNMTEDDWRWHMYDTVKGSDWLGDQDAIHYMCREAPSTVIELENYGVPFSRTPEGKIYQRAFGGQSLKYGKGGQAYRCAAVADRTGHAILHTLYGQSLRHNTNYFIEYFALDLIMEDGECKGVIALNMEDGTIHRFRSHKTVLATGGYGRAYFSCTSAHTCTGDGNAMVARAGLPLQDLEFVQFHPTGIYGSGCLITEGSRGEGGYLVNSAGERFMERYAPTAKDLASRDVVSRAMTMEIKAGRGVGAEKDHIFLQLHHLPPSVLHERLPGISETAAIFAGVDVTKEPIPVLPTVHYNMGGIPTRYTGEVIKVNEKGEDEVVPGLYAAGEAACVSVHGANRLGANSLLDIVVFGRAVAHHIAETLEPNTPLKPFAADAGAKTLANLDQLRNATGPKRTSEIRLNMQKVMQSDAAVFRTQETLDEGVVKIDKVWNSFKDVGVTDRGMIWNTDLVETLELQNLLTCASQTMHSAAVRKESRGAHARDDFTERDDENWMKHTLSYQNQETGEVTLSYRSVTDTTLDEAECKPVPPFARVY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N6T2</accession>
    <name>A0A1C7N6T2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Receptor for retinol uptake STRA6</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">A0J61_07149</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000467">
        <property type="protein sequence ID" value="OBZ84802.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N6T2"/>
    <dbReference type="STRING" id="101091.A0A1C7N6T2"/>
    <dbReference type="InParanoid" id="A0A1C7N6T2"/>
    <dbReference type="OrthoDB" id="2376984at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0038023">
        <property type="term" value="F:signaling receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026612">
        <property type="entry name" value="STRA6-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21444">
        <property type="entry name" value="COILED-COIL DOMAIN-CONTAINING PROTEIN 180"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21444:SF15">
        <property type="entry name" value="RECEPTOR FOR RETINOL UPTAKE STRA6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14752">
        <property type="entry name" value="RBP_receptor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0675">Receptor</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0732">Signal</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008889516" description="Receptor for retinol uptake STRA6" evidence="9">
        <location>
            <begin position="20"/>
            <end position="863"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="299"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="337"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="376"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="495"/>
            <end position="520"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="549"/>
            <end position="574"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="624"/>
            <end position="650"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="662"/>
            <end position="682"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="709"/>
            <end position="730"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OBZ84802.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="12">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="863" mass="100410" checksum="25787AB522DF8B71" modified="2016-11-30" version="1">MLWLFWLTLFELHFNLNGAFTTQCWEVLNGGMHRIFLTTFPLRSKENMFVDGSCQQISMLSNRGWRTQEADDWIYYPQQSVNVSLTAAKVSMALVGGCCAPNRHKSTGFLYQDDGSSFSETGNKIVAIADRPMVQDIFVTGWYMKRFVDDHAMNLTIIPTTHHSDKQAIFYEVVAFDRAMMVNYQFYDYEDKFIGNHTSGLLRNQISIPDITLPKYTRRITVEFYGSRANPICFSYLYAGLYVYSQFATLSKVCSKVASVLQYASLINFLFFLERNQQVNMVLINDAFFRPIRFLCRTPSHKILMCIIVALGSFILNQAWNILNSQSSIFDQWLPRAAKIVGFFATCMLFGLRLSLDLPSLAITYARSQSFLTINLLAAIPTFVAYCSILLYFATKYITFQPCYVCEIEFLEVEDIEEEYVKRLMRRSNEEKPKAPKYFFSFQMISYVIAEKPWQVDPANLLKRISQPRFLMMCIRKLFGIHPYVRIPFAIKTSLILLLYCLGQLIPLLLTQMIGVGGVVPRHICNWSPYLTQLQHHPDPMQFAITTFYLLQIAVYVATLGAGGFCMIYSLGILRRFTKDILRLRQGDYFLFKGKKDHEYVIERSCTYVLMISTSFDLDDAIRFLGVFIGFGFTGTLYFMVEISLIGAFMTATIQLDRLREAFFRHVGYGVFFVSFFVALIVQMIQKRITNLIFIENRSRFTIQNRGPLLHYWYFMMLTSMTRALTSYLIRTLKLILRYPLFSLRVDRNAETWSVRRGDGGFTAYCGMLLAEHEYNNPVVLVFVECLMHMIESRQGQKESEKKLCRTHKRKNVHPDDCLLELHQEFLTDKHNHHLPSPRARSRWFLAYTLIHNPGLRRYRLEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N7C3</accession>
    <name>A0A1C7N7C3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Large ribosomal subunit protein bL28m</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">MRPL24</name>
        <name evidence="5" type="ORF">A0J61_07427</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the bacterial ribosomal protein bL28 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000500">
        <property type="protein sequence ID" value="OBZ84526.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N7C3"/>
    <dbReference type="FunCoup" id="A0A1C7N7C3">
        <property type="interactions" value="211"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N7C3"/>
    <dbReference type="InParanoid" id="A0A1C7N7C3"/>
    <dbReference type="OrthoDB" id="361870at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005762">
        <property type="term" value="C:mitochondrial large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.170.40:FF:000003">
        <property type="entry name" value="54S ribosomal protein L24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.170.40">
        <property type="entry name" value="Ribosomal protein L28/L24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00373">
        <property type="entry name" value="Ribosomal_bL28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026569">
        <property type="entry name" value="Ribosomal_bL28"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034704">
        <property type="entry name" value="Ribosomal_bL28/bL31-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037147">
        <property type="entry name" value="Ribosomal_bL28_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13528">
        <property type="entry name" value="39S RIBOSOMAL PROTEIN L28, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13528:SF2">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN BL28M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00830">
        <property type="entry name" value="Ribosomal_L28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143800">
        <property type="entry name" value="L28p-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 5" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008760"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00035269"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OBZ84526.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="126" mass="14191" checksum="57E8B174B43E8333" modified="2016-11-30" version="1">MLSAQPAYSLARATFKRAQRGLFGGKHIQFGNNNPFSKKKTRRNWLPNVQSKNIYSESLSEFIKLKVTTSVLRTIDKKGGLDKYLLDTKDKNLFSEKAVELKNKIINHNKLQSKKVSSSSEASTSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N7Q5</accession>
    <name>A0A1C7N7Q5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF7721 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_06821</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000430">
        <property type="protein sequence ID" value="OBZ85132.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N7Q5"/>
    <dbReference type="STRING" id="101091.A0A1C7N7Q5"/>
    <dbReference type="InParanoid" id="A0A1C7N7Q5"/>
    <dbReference type="OrthoDB" id="2290255at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056138">
        <property type="entry name" value="DUF7721"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39477:SF1">
        <property type="entry name" value="BETA-FLANKING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39477">
        <property type="entry name" value="CHROMOSOME 8, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24845">
        <property type="entry name" value="DUF7721"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF7721" evidence="2">
        <location>
            <begin position="62"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="149"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="183"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="18"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="48"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="70"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="149"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="185"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="217"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="258"/>
            <end position="322"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF24845"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ85132.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="413" mass="43823" checksum="372F5455D363F2D6" modified="2016-11-30" version="1">MSYYPGEAASYQGGEAASYQGSGSNNNYNHNNNYGYPPPQQNTYGYPSPQQNQSYGYPSPSANDDRHTFDSTYSNIMSNTSRHQPAHDDEIRAAQQSYEQVMSNPQQNNSPDAVGNAAAVHALQRSQQTGGGMSDMIQMAMAQAAKMFGNSSSQGASGQKNDSGKSQAIQQAAMMAMKLYMSKQSSGNQASGHSSSSGGSGAAISSLLGMLMGGSQSGQQQQHQQQQQQQQQQQQHSSSGMGGIGAMVGSLLSGNSGGHSSSQSQQSHGNNNNNYYPPPNNSGNQQYGGNNNYYPPPNNSNYNQHSQGYNQVPPQAQQQQHQGSDFGAMASNLMSKIKGLHLSVENISSRANNNESKKAAIMVNPVAAVTDDPRLVLLLEVLAEGTEELLLLRLVAEPSALTQAVVLSVAVLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N7R4</accession>
    <name>A0A1C7N7R4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Kinetochore protein NDC80</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">ndc80</name>
        <name evidence="14" type="ORF">A0J61_06839</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity.</text>
    </comment>
    <comment type="subunit">
        <text evidence="10">Component of the NDC80 complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Chromosome</location>
            <location evidence="10">Centromere</location>
            <location evidence="10">Kinetochore</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="10">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 10">Belongs to the NDC80/HEC1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000432">
        <property type="protein sequence ID" value="OBZ85111.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N7R4"/>
    <dbReference type="FunCoup" id="A0A1C7N7R4">
        <property type="interactions" value="230"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N7R4"/>
    <dbReference type="InParanoid" id="A0A1C7N7R4"/>
    <dbReference type="OrthoDB" id="7459479at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031262">
        <property type="term" value="C:Ndc80 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051315">
        <property type="term" value="P:attachment of mitotic spindle microtubules to kinetochore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.1950">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.418.30">
        <property type="entry name" value="Ncd80 complex, Ncd80 subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005550">
        <property type="entry name" value="Kinetochore_Ndc80"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055260">
        <property type="entry name" value="Ndc80_CH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038273">
        <property type="entry name" value="Ndc80_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10643">
        <property type="entry name" value="KINETOCHORE PROTEIN NDC80"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10643:SF2">
        <property type="entry name" value="KINETOCHORE PROTEIN NDC80 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03801">
        <property type="entry name" value="Ndc80_HEC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 10" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="3 10" id="KW-0132">Cell division</keyword>
    <keyword evidence="9 10" id="KW-0137">Centromere</keyword>
    <keyword evidence="2 10" id="KW-0158">Chromosome</keyword>
    <keyword evidence="6 11" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5 10" id="KW-0995">Kinetochore</keyword>
    <keyword evidence="4 10" id="KW-0498">Mitosis</keyword>
    <keyword evidence="7 10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Kinetochore protein Ndc80 CH" evidence="13">
        <location>
            <begin position="92"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="11">
        <location>
            <begin position="278"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="11">
        <location>
            <begin position="493"/>
            <end position="527"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="11">
        <location>
            <begin position="557"/>
            <end position="588"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007050"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022838"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU368072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF03801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="OBZ85111.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="631" mass="73050" checksum="3FF960407E4A8F5D" modified="2016-11-30" version="1">MNKEELNKRLSISRKRPASTIPSRAQPIAKRPQMGLTTAMNSLNVNQSNLGLQTNLNQDGHSRLSHVAGSSPTVTEDYSEILRRFNAGDTFETKKHTVDTQSIKDPEKQKQSLREITEYLKRSGYSGPYIRNINILGNREFQAIFKHLVAKASPHYIYKKRFEEDVIILIRQLGYPAADTINRKELLSIGAMHSNPTFIALLHWLVLVCKIMDTPLIPDATEDETNKDMDEHDLAQLLHAYAIAGYHKYMSGNDDTTELDRQLESIFEQANQPNLEKIEEHTRVIAELEQEIASLEADDGELETLKERSTVLAKDIGKYKAYIEEKTKKINKYKSMVERAGEEKKRLEQQLQNIQQQVEASRAKMAEKNVSEEELTAVYERVKVLEKEHAELGKTAEESRQAYQEKTSKLNRYKEQVEKLVEEYNQKARALDSSILQGENILIQYNPSGKTLKEKTDVDIEEELQPKLERFEKEAADETTRLLSQTAILRQELDNFKLENSHIKEDIRQQEERVENLKRLYKENHAIYFQEIGKFNKMKDDIVQGWNAKQSIMRKELLDLQDEVRAAEIRLEEVTEKSKRKKQEAEKKLIPVLERVKTFFEQACQKANEHNQAVNKLLEGMFETFSALNID</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N8F9</accession>
    <name>A0A1C7N8F9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_06540</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the sel-1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000399">
        <property type="protein sequence ID" value="OBZ85410.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N8F9"/>
    <dbReference type="InParanoid" id="A0A1C7N8F9"/>
    <dbReference type="OrthoDB" id="2212001at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006597">
        <property type="entry name" value="Sel1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050767">
        <property type="entry name" value="Sel1_AlgK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11102:SF160">
        <property type="entry name" value="ERAD-ASSOCIATED E3 UBIQUITIN-PROTEIN LIGASE COMPONENT HRD3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11102">
        <property type="entry name" value="SEL-1-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08238">
        <property type="entry name" value="Sel1"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SMART" id="SM00671">
        <property type="entry name" value="SEL1"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81901">
        <property type="entry name" value="HCP-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="13"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="38"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="70"/>
            <end position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00038101"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ85410.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="600" mass="67778" checksum="F795D5C15104C746" modified="2016-11-30" version="1">MAKGFFSRLFGGLAKSNKNKNASQTDSPAPDIKRPPLNQITSSNKVNHTPVSSEQSKPSPSRKPIPLLPQPQQLSKKSSLLRIDKDEDSSYFASDTKNRLTDMNEFINTLNKNDTSLYMKNLDRLSDHVSYQRNSINDEYLTISSAASSKLSLQDALFSHLSMSDCQSEASEYSNFPKIAVHAPFERPISVASSIQLIDPEDTLSSQEESMHYEKQFCDVYMNALRCLSTNPLEALQMFEWLARHGRQVYNKLNKRTQDLVSLAQYRTGRMLYESHSSEQEQEGYTYLIESSQNGHVRATFILGFYAEQKGDLVRACQLYHQAAVLGLLPAKVAFGNILLFKKQINGFQHEDAIRMLDEASRQGHAIASLSLALYYEKVNQIEEATFYCQHVQISPSSPIYCISQYQISIIYLKAGKTFVGKAFECMASAARADYYEEDGSLTKFTPALRKLGVLTLLGIGTAKNAAAAFQFIQEAAKYGDEPANILLGQMYLMGLGCPAVDRSRAMEIFINYHDNIAAKLSRGLLIMQENPQHAYREFIDVLRHEPTAFDQEHWNIRAIKYEASVRIAIWEYNGIGGAEKNPVRAFQXFFFFARIIHLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N8N8</accession>
    <name>A0A1C7N8N8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="8">UV-damage endonuclease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">uve1_0</name>
        <name evidence="8" type="ORF">A0J61_08236</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000616">
        <property type="protein sequence ID" value="OBZ83714.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N8N8"/>
    <dbReference type="FunCoup" id="A0A1C7N8N8">
        <property type="interactions" value="433"/>
    </dbReference>
    <dbReference type="InParanoid" id="A0A1C7N8N8"/>
    <dbReference type="OrthoDB" id="541883at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043504">
        <property type="term" value="P:mitochondrial DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006289">
        <property type="term" value="P:nucleotide-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009411">
        <property type="term" value="P:response to UV"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.150">
        <property type="entry name" value="Divalent-metal-dependent TIM barrel enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004601">
        <property type="entry name" value="UvdE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036237">
        <property type="entry name" value="Xyl_isomerase-like_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00629">
        <property type="entry name" value="uvde"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31290">
        <property type="entry name" value="UV-DAMAGE ENDONUCLEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31290:SF5">
        <property type="entry name" value="UV-DAMAGE ENDONUCLEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03851">
        <property type="entry name" value="UvdE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51658">
        <property type="entry name" value="Xylose isomerase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0227">DNA damage</keyword>
    <keyword evidence="4" id="KW-0228">DNA excision</keyword>
    <keyword evidence="6" id="KW-0234">DNA repair</keyword>
    <keyword evidence="2 8" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0540">Nuclease</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="361"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="436"/>
            <end position="501"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="458"/>
            <end position="471"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022769"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OBZ83714.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="501" mass="57184" checksum="D1A8A08AE10BAFE5" modified="2016-11-30" version="1">MTKQAITSITVETFSTLQTDDSKVTKKTKEKQTTRVMDTSRYVHPNPHEFKGRIGYACLNTILRTQKPPVFCSRTCRLDTIAKKGSDYLKELALANVVDMKKMIQWNEDNKIKFLRLSSEMFPFASHEKAGYDIDFAEKELAEAGELARKYNHRLTTHPGQFNQLVSPNPKVVNNTVRDLSYHARMLDLMGMDQDSVMIIHMGGVYGDRESAIARFEQEFAKLPEFVKRRIVLENDEFGYSVSDLLPVSKKLKIPIVLDCINPGEITDLISVLPEINHVWHERGIRPKQHYSESRTGAKTATELRAHSDRVQFLPPTSDDVDLMIEAKDKEQAVFQLYKLYDLEHVDNNVWVPKTGVGSLKTGGRQTHKAAKSKAQIEQAPEPDVTMKIEDEVEVEVSTRPRRSRRISSVSIAELKKKEAEVEAIQFSLEREQERLEKKKLKSKKEEEGVVKKPKKRTVAESDSKPKDKPTKKTKKSTTLSDRKKKAHIDFEVKSVETMGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N8P7</accession>
    <name>A0A1C7N8P7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_08226</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000613">
        <property type="protein sequence ID" value="OBZ83724.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N8P7"/>
    <dbReference type="InParanoid" id="A0A1C7N8P7"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="20"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="42"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ83724.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="59" mass="6625" checksum="90EA4A6CC82C4BF0" modified="2016-11-30" version="1">MAGSSHQNLWHRSTGGSVDYDGKSEVRDNGFTENINMNIIGNKRERSPHDQTQESSNHP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N983</accession>
    <name>A0A1C7N983_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein C11E3.10</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">A0J61_06251</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000369">
        <property type="protein sequence ID" value="OBZ85693.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N983"/>
    <dbReference type="InParanoid" id="A0A1C7N983"/>
    <dbReference type="OrthoDB" id="63581at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006976">
        <property type="entry name" value="VanZ-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF037970">
        <property type="entry name" value="vanZ_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28008">
        <property type="entry name" value="DOMAIN PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G10980)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28008:SF1">
        <property type="entry name" value="DOMAIN PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G10980)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04892">
        <property type="entry name" value="VanZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008889551" evidence="2">
        <location>
            <begin position="21"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="36"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="60"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="90"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="domain" description="VanZ-like" evidence="3">
        <location>
            <begin position="32"/>
            <end position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF04892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OBZ85693.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="144" mass="16381" checksum="5AC6A6BF13FC7165" modified="2016-11-30" version="1">MRLSVLIALFFFLLFMGILGFAPVHLSEHINDKVLHFFVFFILSMLLYFLWDLSIKLNTILASSILIIIATGSELIQGLLPYRTFDLYDILSNILGGLLGVSLSALSQYSLTQYRVKKRMSGGRKEAESQMALMDFTEDDEEFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N9I6</accession>
    <name>A0A1C7N9I6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Nucleolar 27S pre-rRNA processing Urb2/Npa2 C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_06205</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000364">
        <property type="protein sequence ID" value="OBZ85741.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N9I6"/>
    <dbReference type="InParanoid" id="A0A1C7N9I6"/>
    <dbReference type="OrthoDB" id="160374at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042254">
        <property type="term" value="P:ribosome biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052609">
        <property type="entry name" value="Ribosome_Biogenesis_Reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018849">
        <property type="entry name" value="Urb2/Npa2_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15682">
        <property type="entry name" value="UNHEALTHY RIBOSOME BIOGENESIS PROTEIN 2 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15682:SF2">
        <property type="entry name" value="UNHEALTHY RIBOSOME BIOGENESIS PROTEIN 2 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10441">
        <property type="entry name" value="Urb2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nucleolar 27S pre-rRNA processing Urb2/Npa2 C-terminal" evidence="1">
        <location>
            <begin position="1305"/>
            <end position="1544"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF10441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ85741.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="1544" mass="174925" checksum="FABAEAEC461871C3" modified="2016-11-30" version="1">MSELTSEKIAKSLKGAGLNSKQRIEKAHEAWSNNAIFFPNKDDFLFEWICTAFTKPNLKKLDDCSLFQLPYWTLLSDLLEHYDDKINMDSNQSAPTIHVNLIASVSTVLQHVYKNCLDQPQIRLDLLSSIHRCLKVLLSDRFSVSYRPAFEHVSAGADQLLTSLAVQVDLCLASPNEPLEQKVLYELVPTALLVLKKFDAQLVLAANQKKIFTSIVDKSLVKLLCVRRRILIVDNTDQIFLQISQLISDIICHVLFHTDTILEYTSVLKELSLEVDGTPEAKVKQTNYVVRLFETLEFMVTKDAEHILDAIDMIPDLFSAFLGSYRQKRNASTAVMQDISRMAEFGFFVYLLRILNLMKEQQVSAYLRAVCQLLKKLLQLNVYSSRNDDIAKSQQNVLXGIADNTIMYLQNDQRYDQGLALDLADVLLKIDFSLIENRIQELWPILLNPVDTAQTSCFNFATSILNTYSASRQLDAFVMDLINGLGKLNSNDMYGMLKKPMFTEPFLKEFSSVVSKSMPAAQALGIFSELQTSLLVKQDSEPALKKQKKEKTKEPSKTNNVLLLARYMVAFTHALKLNRHQLSTFEPLVKSIYDDFVKPSINANQSAQNTLLPALQIHFALITAFFDIYVSKFKPSQLEWLADAYLRIFDKHRSEDTLESSMTVVATANAMLQHAYYSSLLQQTATKQTTSLVNKVIDFVIETSDNSVWYQETQWNGSMLDLTNANTVKLACWKLISDEWFDSVAKWIDSGRAEKIALIIFTSLANDNAVSEDVISAQLLNTSLLRSANFYEAKCFKECNIQAILDIFIGFAVDLSSSKSNQICQVAMDTISKMKAVQPFVVEQATIQPLLNALKSSKNMMDEDEQKGSTRYVEKMTQLMKLLLIFPIEYYEKNERTQTIYLATLIDIWSTHYSSASPLSRARLSLMARTLQLRFIDYFSIHSIMGLEPLVLDWFVSSSQGWDLEDVVLLDSLEHTTSEIDQQVLRRMIMNASSKTPDQHAYRYLQDTLKQRIADLERNDDQVTLVKLIHLLCAINSVLAHRKVSEADLTNIAYAADTMSYISQYIIASLQAGKTTVTTLSKKMSDNSDSRQQIFIDYQDAFVTIKHIFHLTRLVQEYAQIVGLAVDEVIAAEELSKTLTSLASPFIQFLQSALQPNEAGYSVVLNMTTEFIAAFCSVSTRYQQIDITKRVLAAVWFVYSLVYKTGDQASISILSKAFASWIQSLSKEQYEIVFQSFVEQAEEESSNRTDNTREERTLVYLSFFSLLMTNCADSEKSRLKKIIPAIILKLSMIAGKTTSFKYMQELLKMLLQLTGDQSYHFKDYDLSLLLSCLLQIAHPTAPKRFEGQIDAESAKKTFADVCSILINLVTHHKEQTVYMMPPFIALVQSLLHCFKSSHVSLVTGKKRKQGDDKTKIKTGRTVSLLTQFAPLDDVSAQRYARVLTTIPQKQHALPTSKSGQTLQRLVAKHTPSILIEYFSIQSNPNMSVVTPSTKSILTNALYDILDVCSEADRNYVLSCLDASGKTLFKSFYTSWKENHKYTGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NA62</accession>
    <name>A0A1C7NA62_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Oligopeptide transporter 5</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">OPT5_1</name>
        <name evidence="11" type="ORF">A0J61_05938</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the oligopeptide OPT transporter family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000337">
        <property type="protein sequence ID" value="OBZ86013.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NA62"/>
    <dbReference type="InParanoid" id="A0A1C7NA62"/>
    <dbReference type="OrthoDB" id="9986677at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035673">
        <property type="term" value="F:oligopeptide transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004648">
        <property type="entry name" value="Oligpept_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004813">
        <property type="entry name" value="OPT"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00727">
        <property type="entry name" value="ISP4_OPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00728">
        <property type="entry name" value="OPT_sfam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22601">
        <property type="entry name" value="ISP4 LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03169">
        <property type="entry name" value="OPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0571">Peptide transport</keyword>
    <keyword evidence="6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="74"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="101"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="143"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="179"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="234"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="307"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="388"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="446"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="472"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="498"/>
            <end position="517"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="556"/>
            <end position="573"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="623"/>
            <end position="643"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="673"/>
            <end position="689"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="701"/>
            <end position="724"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022856"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="OBZ86013.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="755" mass="84794" checksum="A7949701F02B6BC6" modified="2016-11-30" version="1">MSKEEANVHNEKVPNDYQEDKVWVKDHSEKHLDQESSNSSIDDNLFSRKNEEDLDIAIINDVAITEDDPTLKAITVRSIIVGVLLAALSASVHQVMSFKPVGIPLTNTFMLIIAYIVCTAWARLLPHGKWINPGPFNVKEHTCIYVTVSAANASAYATYILSAQQLYYNDSVPSPAGQIFFLLGSQMVGYGIAGNLRKFLVYAPNMTWPTTLPVVSLLKTFNADREGSRWRTKFFFIVFLSAFVYEFIPQYIFPMLGGISIICLARNDSAWVQRLFGGLGTNEGLGIFQFSFDWNLLSNYTPLVIPLWIQLNVYGGVLLLWILAPVMYYYNVWNAQKFPFLSLSLYQLHDNGTVNVYPQSQVLNADYSLNQTLLEQVGRPHFTMVNSLNYVAINFGITATITHVALFYGKEIVAAFRNTKNSFKASAENDDIHMKLMRAYPEVPNWWYILIYLAGMGLNIGIAYANKSQLPWWGVIFAIVLASLLSLPLNMIMAVTGYGFGLNVVTEMVCGFVLPGYPIANMYFKTLGYTTKNQAGILAQDLKIGHYLKVPPRMTFLHQILGTVIGCIFNYIVNDSITTSKHDILLETGNQFWSGSSPQQINSAAITWGAVGPLAMFGPGTEYYIFLWAFVIGFVLPVPGWLLHKKWPKAGFNYINVPMILHGFSLMPGSNTSWIMISFMIVLVSQGYLKRRYSSWFAKHNYLVSAALDSGTSLMVFFISMALYGGANGISYNFPTWWGNRNDVKYMDQCCMNCS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NA96</accession>
    <name>A0A1C7NA96_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Phospholipase</fullName>
            <ecNumber evidence="7">3.1.4.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">pld1_2</name>
        <name evidence="10" type="ORF">A0J61_07674</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 12">
            <text>a 1,2-diacyl-sn-glycero-3-phosphocholine + H2O = a 1,2-diacyl-sn-glycero-3-phosphate + choline + H(+)</text>
            <dbReference type="Rhea" id="RHEA:14445"/>
            <dbReference type="ChEBI" id="CHEBI:15354"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57643"/>
            <dbReference type="ChEBI" id="CHEBI:58608"/>
            <dbReference type="EC" id="3.1.4.4"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the phospholipase D family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.4.4" evidence="7"/>
    <dbReference type="EMBL" id="LUGH01000532">
        <property type="protein sequence ID" value="OBZ84274.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="FunCoup" id="A0A1C7NA96">
        <property type="interactions" value="556"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NA96"/>
    <dbReference type="InParanoid" id="A0A1C7NA96"/>
    <dbReference type="OrthoDB" id="14911at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004630">
        <property type="term" value="F:phospholipase D activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035556">
        <property type="term" value="P:intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006654">
        <property type="term" value="P:phosphatidic acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009395">
        <property type="term" value="P:phospholipid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd09138">
        <property type="entry name" value="PLDc_vPLD1_2_yPLD_like_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd09141">
        <property type="entry name" value="PLDc_vPLD1_2_yPLD_like_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.870.10:FF:000011">
        <property type="entry name" value="Phospholipase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.870.10">
        <property type="entry name" value="Endonuclease Chain A"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025202">
        <property type="entry name" value="PLD-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001736">
        <property type="entry name" value="PLipase_D/transphosphatidylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016555">
        <property type="entry name" value="PLipase_D_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015679">
        <property type="entry name" value="PLipase_D_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18896:SF76">
        <property type="entry name" value="PHOSPHOLIPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18896">
        <property type="entry name" value="PHOSPHOLIPASE D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00614">
        <property type="entry name" value="PLDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13091">
        <property type="entry name" value="PLDc_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF009376">
        <property type="entry name" value="Phospholipase_D_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00155">
        <property type="entry name" value="PLDc"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56024">
        <property type="entry name" value="Phospholipase D/nuclease"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50035">
        <property type="entry name" value="PLD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5 7" id="KW-0442">Lipid degradation</keyword>
    <keyword evidence="6" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="PLD phosphodiesterase" evidence="9">
        <location>
            <begin position="666"/>
            <end position="693"/>
        </location>
    </feature>
    <feature type="domain" description="PLD phosphodiesterase" evidence="9">
        <location>
            <begin position="975"/>
            <end position="1002"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1101"/>
            <end position="1197"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1219"/>
            <end position="1257"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="23"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="1106"/>
            <end position="1129"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="1172"/>
            <end position="1197"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="1230"/>
            <end position="1253"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000798"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022963"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRNR" id="PIRNR009376"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OBZ84274.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="1412" mass="163425" checksum="9CF63749A566EF64" modified="2016-11-30" version="1">MSTSNIPADSIKQSMTKDLPPQLNEQIPNNKTYQNGHKQPMVHSESDYFGQFSPQRSKLPVGQSFMSLPSKPTAPPHPSKQSKPAHRGLLQRVETAPQDGWKLVKKWIGNNKSQLRMVKQTMNLERQAETNMLSPLVLAMFLSKDDDEKNARRIPVFLNNITVKVTKEEDDDSSMTNFSKGSSDGRKNKFRGTTFKIIVQYGTGSGKISWFVFRRYWDFVKLHYHYKYMNSNLDSKSGNGLLYKQTKPPNFPSIPKQYFRRNKLSAGHRHPINTQQSEQYVGIDSDITQHTPFIMDEEAVMALVTINEEEPNAFTPSITGMPAPTHRPFSQIVDIVRADQDVLHAMEDYLNQLVSNLVFCRNINRLCRFLEISNLGVHLSAKYPKSSYHGKEGYAFFQSRTDRDPRHKRTRFQDGLVCSLPTAGGKRKRKPKWFIVRDSYVVCVDSPSETEIYDVFLFDQMFDIHRLALFSDKRSHAKGNRKKVKNAIANASHWTSGRSTLCFKNMNGVYHFRAKDENTARQFERSIQMAARHSLWCQVNRFKSFAPVRENVPATWYVDGRDYFWDLSVALENATECIYIHDWWLSPELFLRRPAASNLEWRLDRVLRRKADQGVKVFIVMYKEVSMALPLFSHQAKRNLLALSPNIYVQRHPSRMLDIFNKDVVFFWAHHEKICVVDNEIAFVGGIDKCFGRWDTPTHAVVDDRDPELTADNQNPQVWSGKDYSNPRIIDFHTLNKPFEDNQDRKTLPRMPWHDISLRIVGPAARDVARHFVQRWNFLRRKKPNAPKRPTPMLLPVPDAYTNKVEERDKRICHPHFSTSCRVQILRSVSPWSIGSTDHVEKSIQNAYVESIRDSKHLVYIENQFFVTTTKSGNTKIENNIGKALYQRIVRAHQLGEKWRAIIIVPLVPGFPANIDETEATTVRIIMQCQYLSVARGPHSLLARLHAAGVLNTHEYINFYGLRNWGELNGQYVTEQVYIHAKTMIVDDQTVIIGSANINERSMLGTRDSEIAACIQEDEKDLVEITFNHQPVRVSRFAHQLRMRLMCEHIGLDVDRMDRERREEVKDYFQEPVWSDCHLDDDDKNDFVNCIPPFIQVTAASSQPLNEKEQAEQERDDLEQVKKKQKAQEEQDLEEQEKRSIAESYLDSSDDTSSESSHATYLHNKLRGEPKQYSTDQKRLSQAQSVQTSDTSKESILSPTKSIFSNHKRKSLKEDYHDFWTSLDPDTDNNGDRRAWEQKRETGESKQEAKASDSEVLESTANYYSSARLDPLCMDHKTVADVYHMLQDPLTDEFQTFWHMLARINTDLFRRCFLVTPDNNVRNWEQYNHFAKMSKLFLGRVDVKHGGTKTTAAAANVTAIPLDESDHLMVKQVLRHIRGHLVVWPSHFMEEEDEQNQFLTNVDKLAPLEIFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NAQ6</accession>
    <name>A0A1C7NAQ6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Ferric reduction oxidase 7, chloroplastic</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">FRO7</name>
        <name evidence="12" type="ORF">A0J61_05771</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000322">
        <property type="protein sequence ID" value="OBZ86182.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NAQ6"/>
    <dbReference type="FunCoup" id="A0A1C7NAQ6">
        <property type="interactions" value="233"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NAQ6"/>
    <dbReference type="InParanoid" id="A0A1C7NAQ6"/>
    <dbReference type="OrthoDB" id="167398at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016175">
        <property type="term" value="F:superoxide-generating NAD(P)H oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006811">
        <property type="term" value="P:monoatomic ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06186">
        <property type="entry name" value="NOX_Duox_like_FAD_NADP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.80">
        <property type="entry name" value="Nucleotide-binding domain of ferredoxin-NADP reductase (FNR) module"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000778">
        <property type="entry name" value="Cyt_b245_heavy_chain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013112">
        <property type="entry name" value="FAD-bd_8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013130">
        <property type="entry name" value="Fe3_Rdtase_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013121">
        <property type="entry name" value="Fe_red_NAD-bd_6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039261">
        <property type="entry name" value="FNR_nucleotide-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050369">
        <property type="entry name" value="RBOH/FRE"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11972:SF69">
        <property type="entry name" value="FERRIC REDUCTION OXIDASE 6-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11972">
        <property type="entry name" value="NADPH OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08022">
        <property type="entry name" value="FAD_binding_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01794">
        <property type="entry name" value="Ferric_reduct"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08030">
        <property type="entry name" value="NAD_binding_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00466">
        <property type="entry name" value="GP91PHOX"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00052">
        <property type="entry name" value="Ferric_Reductase_Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01168">
        <property type="entry name" value="Ferric_reductase_subgroup_(FRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52343">
        <property type="entry name" value="Ferredoxin reductase-like, C-terminal NADP-linked domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0249">Electron transport</keyword>
    <keyword evidence="6" id="KW-0406">Ion transport</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="14"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="89"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="121"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="161"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="202"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="226"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="domain" description="Ferric oxidoreductase" evidence="9">
        <location>
            <begin position="124"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding 8" evidence="10">
        <location>
            <begin position="290"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="domain" description="Ferric reductase NAD binding" evidence="11">
        <location>
            <begin position="440"/>
            <end position="577"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01794"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF08022"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF08030"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="OBZ86182.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="592" mass="69506" checksum="63E2C9471F91EF95" modified="2016-11-30" version="1">MEFKLPYIRTWTNFWILGMAYAFFCWSIFIAYCIYYQVSRLSIYRSRSRRINGKEDSSILEPHKFRLLHRLNHVVRIPYTTELISVKQIVGTILFGLINLYFIFFVYPYEFAPYHVAILDRRAAFIGMVDWSLVFFFAQRNSLLPKICGLTFEELMPFHRIFARIGFLTFIPHFIYRVYYAYMIKYSWFDAFFQDIEYTTGTIATIAYIVMFATSIEYIRRNHFEVFYYCHVLFLVVAIVFTCWHYPTCFAFYIPAVSLWIADRMVRFYKSWIIKSSFVSIQQVVAQTATQEGVVHISFQNKLLNRFKPGQYLFAAIVLNKRRFWEYLNWHPFTISEVYEASPEINKSEEHNICATKTTSETTGLLQSPQTSYLTSPSHLKQRRPSVCKDKIASIHIKSLGTKTNDLLNASSADNKMASELKVYIDGLYGPQLPYQDYPILALFATGIGVTPAIAIIQDVIRKRSNGVRTVASNNIRLYWSIRHTDEIDPFMNMFSQWNQQVQNAIMPVELNVNIYVTRMTQQRHSIQQFSNFHLNFNGRPQIDAEMRMIKANNTQGQRTWVHVCGSTAFTRTVINEAVKADFDIHHEIFEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NAZ1</accession>
    <name>A0A1C7NAZ1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Vesicular integral-membrane protein VIP36</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">Lman2</name>
        <name evidence="8" type="ORF">A0J61_06036</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass type I membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000345">
        <property type="protein sequence ID" value="OBZ85919.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NAZ1"/>
    <dbReference type="FunCoup" id="A0A1C7NAZ1">
        <property type="interactions" value="339"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NAZ1"/>
    <dbReference type="InParanoid" id="A0A1C7NAZ1"/>
    <dbReference type="OrthoDB" id="270293at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030134">
        <property type="term" value="C:COPII-coated ER to Golgi transport vesicle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005793">
        <property type="term" value="C:endoplasmic reticulum-Golgi intermediate compartment"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005537">
        <property type="term" value="F:D-mannose binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006888">
        <property type="term" value="P:endoplasmic reticulum to Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051136">
        <property type="entry name" value="Intracellular_Lectin-GPT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005052">
        <property type="entry name" value="Lectin_leg"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12223:SF45">
        <property type="entry name" value="RE50040P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12223">
        <property type="entry name" value="VESICULAR MANNOSE-BINDING LECTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03388">
        <property type="entry name" value="Lectin_leg-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51328">
        <property type="entry name" value="L_LECTIN_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="199"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="domain" description="L-type lectin-like" evidence="7">
        <location>
            <begin position="1"/>
            <end position="173"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OBZ85919.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="229" mass="26035" checksum="7639E5BF8ED710FF" modified="2016-11-30" version="1">MVSFVGDNFQIEFEFKVDGNSGHLYGDGFAMWLTKQRMTEGPVFGSADHFQGLGVFFDTYDNERSHRHTFPYVMAMLGDGMKSYNNDKDGSDQELAGCEADFRARGFPTKARLTYYKNNYIKLELVWRQDDEWEMCFKKHGVVLPEQIYLGFSAHTGEVTDNHDIISVITKSLVPAAMEAAPQVPRPKKESSSGSVLSVLFKMLLAAGLVGVLFVGYRFYDQKNRMKRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NBD9</accession>
    <name>A0A1C7NBD9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Phospholipase B1, membrane-associated</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">PLB1_0</name>
        <name evidence="3" type="ORF">A0J61_07298</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000485">
        <property type="protein sequence ID" value="OBZ84654.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NBD9"/>
    <dbReference type="STRING" id="101091.A0A1C7NBD9"/>
    <dbReference type="InParanoid" id="A0A1C7NBD9"/>
    <dbReference type="OrthoDB" id="10265800at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004620">
        <property type="term" value="F:phospholipase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006644">
        <property type="term" value="P:phospholipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1110">
        <property type="entry name" value="SGNH hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001087">
        <property type="entry name" value="GDSL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008265">
        <property type="entry name" value="Lipase_GDSL_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038885">
        <property type="entry name" value="PLB1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036514">
        <property type="entry name" value="SGNH_hydro_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21325:SF31">
        <property type="entry name" value="GH22081P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21325">
        <property type="entry name" value="PHOSPHOLIPASE B, PLB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00657">
        <property type="entry name" value="Lipase_GDSL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52266">
        <property type="entry name" value="SGNH hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01098">
        <property type="entry name" value="LIPASE_GDSL_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008889590" evidence="2">
        <location>
            <begin position="18"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="293"/>
            <end position="320"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ84654.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="396" mass="45249" checksum="AD31B4EDA2BAE448" modified="2016-11-30" version="1">MWISLLSLYFLLHTILGHQVVLKQTNQIGGPFSYEWLHMLEQFHNTFGNRTKDDTHCLFPTPTFDCQPFLWDDGIVKRDAYHLRPQDIKSIIAIGDSMTAGFGMISGRPPFATVLEYRGKVFSVGGDPGEHTLPNFFSIYSGASQTGASKGTTLPKSKGKQLNNAISGAKAQDLDDELDRLTRMMQYEKYKHIKDDWKLITLFIGANNVCELCQPPFSRLPELADADVFEANVRAMLERIRTDVGKSFVNLVALFNVSSVYEASREDPYCRMVLDPSHMVICSCIQGNEKQRQGTADRIVDEYNRRLQKLEREFKHKDIHQLGVSYQPSFADFPVSKYKQAYFSGVDCFHPNKCGNQVMATLLWNNMFSNQIEKRKKWDVETLQFVCPSAHQPYIQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NBG5</accession>
    <name>A0A1C7NBG5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Large ribosomal subunit protein mL49</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">img2_0</name>
        <name evidence="7" type="ORF">A0J61_05609</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the mitochondrion-specific ribosomal protein mL49 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000308">
        <property type="protein sequence ID" value="OBZ86330.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NBG5"/>
    <dbReference type="FunCoup" id="A0A1C7NBG5">
        <property type="interactions" value="73"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NBG5"/>
    <dbReference type="InParanoid" id="A0A1C7NBG5"/>
    <dbReference type="OrthoDB" id="19439at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005762">
        <property type="term" value="C:mitochondrial large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.780.10">
        <property type="entry name" value="SUI1-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007740">
        <property type="entry name" value="Ribosomal_mL49"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13477:SF0">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN ML49"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13477">
        <property type="entry name" value="MITOCHONDRIAL 39S RIBOSOMAL PROTEIN L49"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05046">
        <property type="entry name" value="Img2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 7" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00035191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OBZ86330.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="100" mass="11392" checksum="5E6C5754FF3AC4A0" modified="2016-11-30" version="1">MLRHIAQSTFQSTKRFYSTPAYTISRTTNKGLPVYSEYKNGNTRLLTIIRRIQGDSNALAKDLVNDFPEAVVQVKPTTKHVVIKGNHVNEIKEWLISKGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NBI9</accession>
    <name>A0A1C7NBI9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">deoxyhypusine synthase</fullName>
            <ecNumber evidence="5">2.5.1.46</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">dhps</name>
        <name evidence="8" type="ORF">A0J61_07251</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Catalyzes the NAD-dependent oxidative cleavage of spermidine and the subsequent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a specific lysine residue of the eIF-5A precursor protein to form the intermediate deoxyhypusine residue.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>[eIF5A protein]-L-lysine + spermidine = [eIF5A protein]-deoxyhypusine + propane-1,3-diamine</text>
            <dbReference type="Rhea" id="RHEA:33299"/>
            <dbReference type="Rhea" id="RHEA-COMP:10143"/>
            <dbReference type="Rhea" id="RHEA-COMP:10144"/>
            <dbReference type="ChEBI" id="CHEBI:29969"/>
            <dbReference type="ChEBI" id="CHEBI:57484"/>
            <dbReference type="ChEBI" id="CHEBI:57834"/>
            <dbReference type="ChEBI" id="CHEBI:82657"/>
            <dbReference type="EC" id="2.5.1.46"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3">Protein modification; eIF5A hypusination.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the deoxyhypusine synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.46" evidence="5"/>
    <dbReference type="EMBL" id="LUGH01000480">
        <property type="protein sequence ID" value="OBZ84704.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NBI9"/>
    <dbReference type="FunCoup" id="A0A1C7NBI9">
        <property type="interactions" value="671"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NBI9"/>
    <dbReference type="InParanoid" id="A0A1C7NBI9"/>
    <dbReference type="OrthoDB" id="294378at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034038">
        <property type="term" value="F:deoxyhypusine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.910.10:FF:000002">
        <property type="entry name" value="Deoxyhypusine synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.910.10">
        <property type="entry name" value="Deoxyhypusine synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002773">
        <property type="entry name" value="Deoxyhypusine_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036982">
        <property type="entry name" value="Deoxyhypusine_synthase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029035">
        <property type="entry name" value="DHS-like_NAD/FAD-binding_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00321">
        <property type="entry name" value="dhys"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11703">
        <property type="entry name" value="DEOXYHYPUSINE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11703:SF0">
        <property type="entry name" value="DEOXYHYPUSINE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01916">
        <property type="entry name" value="DS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52467">
        <property type="entry name" value="DHS-like NAD/FAD-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0520">NAD</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000952"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005041"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00009892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012683"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OBZ84704.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="359" mass="39937" checksum="87CA97EA2AD19129" modified="2016-11-30" version="1">MSQPTGALDAVFVESVEMPEGSVLIQGPDFNKRLSLSQLLGSYKQMGYQGSSLGEAMDIIKAMRAWRLSDEPIGDDEAPEYLDPEVRAKTKCKIFLGYTSNLVSSGLREIIRFLAEHKMVDVIVATAGGVEEDFIKCLAPTYLGDFNLKGSDLRKKGLNRIGNLLVPNNNYCKFEDWVIPIFDQMLEEQKTKNVIWTPSSMIQRLGQEINDPSSIYYWTSKNNIPVFCPAITDGSLGDMLYFHSYKNPGLIVDINQDIRAMNNQAVFAKKTGMIILGGGVIKHHICNANLMRNGADYAVYINTGQEFDGSDAGARPDEAVSWGKIRADSRSCKIYADATLVFPLIVAETFAKEHHEQQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NC27</accession>
    <name>A0A1C7NC27_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Late secretory pathway protein AVL9</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">AVL9</name>
        <name evidence="4" type="ORF">A0J61_05311</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the AVL9 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000283">
        <property type="protein sequence ID" value="OBZ86645.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="FunCoup" id="A0A1C7NC27">
        <property type="interactions" value="450"/>
    </dbReference>
    <dbReference type="InParanoid" id="A0A1C7NC27"/>
    <dbReference type="OrthoDB" id="192887at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11500">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018307">
        <property type="entry name" value="ABL9/DENND6_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043153">
        <property type="entry name" value="DENN_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051731">
        <property type="entry name" value="DENND11/AVL9_GEFs"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037516">
        <property type="entry name" value="Tripartite_DENN"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31017:SF1">
        <property type="entry name" value="LATE SECRETORY PATHWAY PROTEIN AVL9 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31017">
        <property type="entry name" value="LATE SECRETORY PATHWAY PROTEIN AVL9-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09794">
        <property type="entry name" value="Avl9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50211">
        <property type="entry name" value="DENN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UDENN" evidence="3">
        <location>
            <begin position="12"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="567"/>
            <end position="619"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00038178"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OBZ86645.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="619" mass="70558" checksum="F5B6EE7C8735EA65" modified="2016-11-30" version="1">MSSNENKDQQIAAILVVGFHHAYGPIAEFCVPPLSNQPKQTTLEKLELPEEWSFLPFLALPDGAHQKDEDFAYFHLPPVPGESTLFGISCNRQIAAKDLEVKTPDITRSTVQKAIVVLARQPIFGPLRQKLAVITAAWFSQKDFTKLDILYNLYNNLNSTYYGPIDDSTLYMGTSLRELVYKFQFRTLILLKLLLLEKRILFYGYPVERLCTFQYSLISLIPGLLRSLQDSGAPNLDSSDDTIQITEAKVLSDRSKDSLLKYMGLPLHLFEKGSFFQPYLPLQQIDLLSSEQTQSYVVGTTNQIFFHHKSDTKIDVLVNVETGILEFYNQQLSHLVSPTLADRRWMEEIVKVVNDTWNQSDPSRPVQNTYNGSDDYLRAKFEEYVLSLLSSMKHAQAHNLLDKVQAHIEPTEEVIMDENEEHNYLTDYGMKWLMVWWNTNNFKKWNQXTDHEIYEIIEPGHPGMGRLSIADVQNTLANRLRDLQLKQNLAPIRNTLSKAMSGGAKAMSSGRSKLNALWSDQERHGEAGQTYDPPLSPLLETTTQQAGRLFSNFSSFLTRKTKEFSQTMEESVSDKRTHQLSRQASSDDDSGSGVFVEGEQMYPFSSKPRRNEEDGILDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-06-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NCE5</accession>
    <name>A0A1C7NCE5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_05175</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000273">
        <property type="protein sequence ID" value="OBZ86773.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NCE5"/>
    <dbReference type="InParanoid" id="A0A1C7NCE5"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ86773.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="299" mass="34748" checksum="3C9D5B713533BF89" modified="2016-11-30" version="1">MQNNNSPVVLALYQPENGISSLNHYYQLVLQPGSPWPETIFNNRQYCSEANFASWQSLYEPQLPNKTNKCTEYVGIDTRLGTTNSPQPPQQAQKIAMYAGIDTRHGKKQLTFKIPKRKELEKVTLTPCKYDFIIEHYTDINRQCDFCGSDFEDEALQLLMQLEYQKYLKEKERPFKYLKSRQKHLANAALTYCKLIEQDDENGLANLLYNSYEDFMSRIKGEGFVHTYRHLAIASKRSTYLALRKAKLKSDQNFNDTLRFSLVPAVGVLLIAEDLYGTKPKYDDNEISWAYMIMNIKLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NCZ5</accession>
    <name>A0A1C7NCZ5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">phospholipase D</fullName>
            <ecNumber evidence="1">3.1.4.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">SPO14</name>
        <name evidence="8" type="ORF">A0J61_06715</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.4.4" evidence="1"/>
    <dbReference type="EMBL" id="LUGH01000419">
        <property type="protein sequence ID" value="OBZ85234.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NCZ5"/>
    <dbReference type="STRING" id="101091.A0A1C7NCZ5"/>
    <dbReference type="InParanoid" id="A0A1C7NCZ5"/>
    <dbReference type="OrthoDB" id="14911at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004630">
        <property type="term" value="F:phospholipase D activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035556">
        <property type="term" value="P:intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006654">
        <property type="term" value="P:phosphatidic acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009395">
        <property type="term" value="P:phospholipid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd09138">
        <property type="entry name" value="PLDc_vPLD1_2_yPLD_like_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd09141">
        <property type="entry name" value="PLDc_vPLD1_2_yPLD_like_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.870.10">
        <property type="entry name" value="Endonuclease Chain A"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025202">
        <property type="entry name" value="PLD-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001736">
        <property type="entry name" value="PLipase_D/transphosphatidylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016555">
        <property type="entry name" value="PLipase_D_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015679">
        <property type="entry name" value="PLipase_D_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18896">
        <property type="entry name" value="PHOSPHOLIPASE D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18896:SF186">
        <property type="entry name" value="PHOSPHOLIPASE D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00614">
        <property type="entry name" value="PLDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13091">
        <property type="entry name" value="PLDc_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF009376">
        <property type="entry name" value="Phospholipase_D_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00155">
        <property type="entry name" value="PLDc"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56024">
        <property type="entry name" value="Phospholipase D/nuclease"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50035">
        <property type="entry name" value="PLD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0442">Lipid degradation</keyword>
    <keyword evidence="5" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="PLD phosphodiesterase" evidence="7">
        <location>
            <begin position="162"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="domain" description="PLD phosphodiesterase" evidence="7">
        <location>
            <begin position="549"/>
            <end position="576"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="480"/>
            <end position="535"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="523"/>
            <end position="533"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022963"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OBZ85234.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="764" mass="88513" checksum="6D8624283148326B" modified="2016-11-30" version="1">MPLLNHFAKKLKHEVRHAINHVVKSEDDLDDREEEYLAQGHRYDSFAPIRNEAMVKYFIDGHDYCWAVSEAIESAKEVIFIEDWWLSPELYLRRPPKKYEEYRIDRLLKKKAEEGVMIYIVVYKEVELAMTLDSAHTKKHLQSMHENIVVQRHPDHAVGGTFFWSHHEKFVVVDNRIAFLGGIDLCYGRWDTHAHRLADFTASDPHYEIFPGQDYSDARLRDFEYVKEWDMRLIDKTIVPRMPWHDMSLCMLGEPVLDVARHFCDRWNFIKQSKSLDKKNAPFLKPPLGGYSSYQSFKIPLESRLLRSYHFDHHTSGIHGSCTVQVLRSSASWSSGIQLEHSIQNAYLDVITNAQHYVYIENQFFITTTEDDPNFIIKNQIGDAIVKRIKKAYDCQEKFKVFVIIPLMPAFPAELSSKDAATARLVMYYQYISICSGEKSIVEKLRKEGIDPAEYIRFYSLRSYDRINRPMVEEMMARDAGLTPHKGGKPLKEQEVERTQVSTPPAGFVLPEQRPQMPDPDRPSSSGSRLSVPTDQFSERLELDDYVTEELYVHAKLLIADDRIVIMGSANLNDRSQCGDRDSEIALMVEDRDMISSMMNGQPYQASRFAATLRRQLWKEHLGMAHEEDELDIVNNAMLPLPVPQIDFTDSEQDKLVMDPLSEETLALWNGTANTNTLAFREVFHCVPDDTITNWNQYHQFYPDPEKIELGHVHDPNMSVHEVRKHLSTIRGHLVEFPLDFLREEDLQGEAIPIVGSAVQELYT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NEF4</accession>
    <name>A0A1C7NEF4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Ubiquitin-conjugating enzyme spm2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">spm2</name>
        <name evidence="3" type="ORF">A0J61_04796</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000242">
        <property type="protein sequence ID" value="OBZ87159.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NEF4"/>
    <dbReference type="FunCoup" id="A0A1C7NEF4">
        <property type="interactions" value="1021"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NEF4"/>
    <dbReference type="InParanoid" id="A0A1C7NEF4"/>
    <dbReference type="OrthoDB" id="6508832at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000329">
        <property type="term" value="C:fungal-type vacuole membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031371">
        <property type="term" value="C:ubiquitin conjugating enzyme complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061631">
        <property type="term" value="F:ubiquitin conjugating enzyme activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006301">
        <property type="term" value="P:DNA damage tolerance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010994">
        <property type="term" value="P:free ubiquitin chain polymerization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000209">
        <property type="term" value="P:protein polyubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044395">
        <property type="term" value="P:protein targeting to vacuolar membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd23807">
        <property type="entry name" value="UEV_UBE2V"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.110.10:FF:000026">
        <property type="entry name" value="Ubiquitin-conjugating enzyme E2 variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.110.10">
        <property type="entry name" value="Ubiquitin Conjugating Enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000608">
        <property type="entry name" value="UBC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016135">
        <property type="entry name" value="UBQ-conjugating_enzyme/RWD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24068">
        <property type="entry name" value="UBIQUITIN-CONJUGATING ENZYME E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00179">
        <property type="entry name" value="UQ_con"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00212">
        <property type="entry name" value="UBCc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54495">
        <property type="entry name" value="UBC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50127">
        <property type="entry name" value="UBC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="UBC core" evidence="2">
        <location>
            <begin position="5"/>
            <end position="136"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ87159.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="136" mass="15203" checksum="395924F16CA99547" modified="2016-11-30" version="1">MAKVPRNFRLLEELEKGEKGLGDGACSYGLADDDLLMHNWHATILGAPHSVHENRIYSLNIYCGDNYPNQPPELQFVSRINLPSVNAQNGKVEANRLPCLAGWKSHYTLETVLTELRREMGTVGRKLPQPAEGTTF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NEQ3</accession>
    <name>A0A1C7NEQ3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Demethylmenaquinone methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">menG_0</name>
        <name evidence="3" type="ORF">A0J61_04383</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000213">
        <property type="protein sequence ID" value="OBZ87567.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NEQ3"/>
    <dbReference type="FunCoup" id="A0A1C7NEQ3">
        <property type="interactions" value="432"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NEQ3"/>
    <dbReference type="InParanoid" id="A0A1C7NEQ3"/>
    <dbReference type="OrthoDB" id="2013972at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041698">
        <property type="entry name" value="Methyltransf_25"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43591:SF24">
        <property type="entry name" value="2-METHOXY-6-POLYPRENYL-1,4-BENZOQUINOL METHYLASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43591">
        <property type="entry name" value="METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13649">
        <property type="entry name" value="Methyltransf_25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransferase" evidence="2">
        <location>
            <begin position="228"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="25"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="62"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ87567.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="460" mass="52670" checksum="B92E0AB55BA6530B" modified="2016-11-30" version="1">MGNTSSSEDKSIRRFSSSKPRRQSNRSSASQRLASSHSSFSPNASFSDFETSSHKHESILSRIKHKANRPRGHSHTSSVSSNSIFNHHLSRLDFFANSLDDDLDKSATTSPSSMYSNQENTIEKYTDSQMTLLSNGNSKHNPLAGIKIHNDSSTTIHSITTNTIQAFPHKQEMTKAFSCDLLLKELYASSETSPERRRERDRRHRQHYLLKRIWGSNHKVPLENPTMIIDWCCGTAVWDLEMAFEFPKAQVVGIDYESFTVSGLTNTVKNFSFRNALIHQGETGLGSFSDNQVDYVMIRDSWLVNSSTSKWTNILKEVYRILKPGGYIELYEQDSNFESLGPHFTILENWATEFYAAIKFERNTVYSLNTILNDLGYTNIQEESVQVPIGEWPQTEELKETGYLQRDLVERKFREGKRWICKANSINEKEFSDTLTAAMEECDRHSTTALNFYFCAQKPH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NER2</accession>
    <name>A0A1C7NER2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">rhizopuspepsin</fullName>
            <ecNumber evidence="3">3.4.23.21</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="primary">CARP_4</name>
        <name evidence="15" type="ORF">A0J61_04326</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Hydrolysis of proteins with broad specificity similar to that of pepsin A, preferring hydrophobic residues at P1 and P1'. Clots milk and activates trypsinogen. Does not cleave 4-Gln-|-His-5, but does cleave 10-His-|-Leu-11 and 12-Val-|-Glu-13 in B chain of insulin.</text>
            <dbReference type="EC" id="3.4.23.21"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 12">Belongs to the peptidase A1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.23.21" evidence="3"/>
    <dbReference type="EMBL" id="LUGH01000210">
        <property type="protein sequence ID" value="OBZ87613.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NER2"/>
    <dbReference type="STRING" id="101091.A0A1C7NER2"/>
    <dbReference type="InParanoid" id="A0A1C7NER2"/>
    <dbReference type="OrthoDB" id="771136at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004190">
        <property type="term" value="F:aspartic-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05471">
        <property type="entry name" value="pepsin_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.70.10:FF:000008">
        <property type="entry name" value="Cathepsin D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.70.10">
        <property type="entry name" value="Acid Proteases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001461">
        <property type="entry name" value="Aspartic_peptidase_A1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001969">
        <property type="entry name" value="Aspartic_peptidase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034164">
        <property type="entry name" value="Pepsin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033121">
        <property type="entry name" value="PEPTIDASE_A1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021109">
        <property type="entry name" value="Peptidase_aspartic_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47966">
        <property type="entry name" value="BETA-SITE APP-CLEAVING ENZYME, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47966:SF51">
        <property type="entry name" value="BETA-SITE APP-CLEAVING ENZYME, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00026">
        <property type="entry name" value="Asp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00792">
        <property type="entry name" value="PEPSIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50630">
        <property type="entry name" value="Acid proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00141">
        <property type="entry name" value="ASP_PROTEASE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51767">
        <property type="entry name" value="PEPTIDASE_A1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 12" id="KW-0064">Aspartyl protease</keyword>
    <keyword evidence="9 11" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="7 12" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 12" id="KW-0645">Protease</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 13" id="KW-0732">Signal</keyword>
    <keyword evidence="8" id="KW-0865">Zymogen</keyword>
    <feature type="signal peptide" evidence="13">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008889661" description="rhizopuspepsin" evidence="13">
        <location>
            <begin position="21"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase A1" evidence="14">
        <location>
            <begin position="56"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="active site" evidence="10">
        <location>
            <position position="74"/>
        </location>
    </feature>
    <feature type="active site" evidence="10">
        <location>
            <position position="309"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="11">
        <location>
            <begin position="87"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="15">
        <location>
            <position position="381"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001130"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013205"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022750"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR601461-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR601461-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU000454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51767"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="OBZ87613.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="381" mass="40432" checksum="4BCF23A409DED576" modified="2016-11-30" version="1" fragment="single">MQIKTAIFISSALLFIQTNAVEEKRLLRVPIRKHTQSHLVKRTSIASLYNDAGSQYLVDIKIGTPAQSFIVTLDTGSSDLWVPGSSCPSTECPNSVFYENQSSTFTSLNTPFGLTYGIGSVNGTYVTDTVSISDATVTSQQFGLATSTSNILTNTNTITTAMAHTNYTLHASVATSTATANGILGLGYPRLTAASSAGSKAYNPFVFNLVANGVISDPVFSIYLNRLEKSGWVGEITFGGIDTSRFSGNLTYMNVVSLASTQTSRSKRASFNTNNYYWMVGAQGISVTGSTNTSTVSYSFNSNSAFILDTGTTLTYLPTAMAKEVIEAVAGTNGYTTDTSSGAYIISCDTSNSDQQVVLKMKASSSSTEPITLAVPISDLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NES2</accession>
    <name>A0A1C7NES2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Sialate O-acetylesterase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_04358</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000212">
        <property type="protein sequence ID" value="OBZ87591.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NES2"/>
    <dbReference type="InParanoid" id="A0A1C7NES2"/>
    <dbReference type="OrthoDB" id="42638at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1110">
        <property type="entry name" value="SGNH hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052940">
        <property type="entry name" value="Carb_Esterase_6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005181">
        <property type="entry name" value="SASA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036514">
        <property type="entry name" value="SGNH_hydro_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31988:SF19">
        <property type="entry name" value="9-O-ACETYL-N-ACETYLNEURAMINIC ACID DEACETYLASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31988">
        <property type="entry name" value="ESTERASE, PUTATIVE (DUF303)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03629">
        <property type="entry name" value="SASA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52266">
        <property type="entry name" value="SGNH hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Sialate O-acetylesterase" evidence="2">
        <location>
            <begin position="54"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="309"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03629"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ87591.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="309" mass="34767" checksum="AD1E421D0525F398" modified="2016-11-30" version="1" fragment="single">MVYNYQDILPFQVLQREPGKDFAEVRKDELRDHKFKIGGPHYYYDGYGKPFYVGDIWVMAGENNMQGLGNKIDFFTMEELQQSVTHDAALLYDSSEHWRRFRQDPSHEPGKSRRVFLRQDVKSNFFCPNILKPGGASLAPAFVNTLNDINSGIPIGLVACAKQNSTIDDWETNSKDPDSSLYGAMLDKIKKVGGRIAGVLWYQGESDAFDSARAKIYGKLFQAWVSQLREDLSQPNLPVVFVQIGPYNLESSEHRNNWKKIQAAQFEMFGQSPYTAGVASMDAMLDSSRDLSASGLSLVGRRLALAADK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NFN7</accession>
    <name>A0A1C7NFN7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Replication factor C subunit 4</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">rfc4</name>
        <name evidence="9" type="ORF">A0J61_04036</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the activator 1 small subunits family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000189">
        <property type="protein sequence ID" value="OBZ87912.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NFN7"/>
    <dbReference type="FunCoup" id="A0A1C7NFN7">
        <property type="interactions" value="419"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NFN7"/>
    <dbReference type="InParanoid" id="A0A1C7NFN7"/>
    <dbReference type="OrthoDB" id="4199794at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031390">
        <property type="term" value="C:Ctf18 RFC-like complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005663">
        <property type="term" value="C:DNA replication factor C complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031391">
        <property type="term" value="C:Elg1 RFC-like complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031389">
        <property type="term" value="C:Rad17 RFC-like complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003689">
        <property type="term" value="F:DNA clamp loader activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902983">
        <property type="term" value="P:DNA strand elongation involved in mitotic DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006272">
        <property type="term" value="P:leading strand elongation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007062">
        <property type="term" value="P:sister chromatid cohesion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070914">
        <property type="term" value="P:UV-damage excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd00009">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18140">
        <property type="entry name" value="HLD_clamp_RFC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.60:FF:000012">
        <property type="entry name" value="Replication factor C subunit 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.272.10:FF:000015">
        <property type="entry name" value="Replication factor C subunit 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000107">
        <property type="entry name" value="Replication factor C subunit 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.272.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008921">
        <property type="entry name" value="DNA_pol3_clamp-load_cplx_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050238">
        <property type="entry name" value="DNA_Rep/Repair_Clamp_Loader"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013748">
        <property type="entry name" value="Rep_factorC_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047854">
        <property type="entry name" value="RFC_lid"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF001679">
        <property type="entry name" value="PRK00440.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11669">
        <property type="entry name" value="REPLICATION FACTOR C / DNA POLYMERASE III GAMMA-TAU SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11669:SF5">
        <property type="entry name" value="REPLICATION FACTOR C SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08542">
        <property type="entry name" value="Rep_fac_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48019">
        <property type="entry name" value="post-AAA+ oligomerization domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0235">DNA replication</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="8">
        <location>
            <begin position="52"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005378"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00070186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OBZ87912.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="333" mass="37519" checksum="42CE8427A81C042A" modified="2016-11-30" version="1" fragment="single">STMDIDHQSNTTNTNDDFIMPWVEKYRPLKLKDIVGNEDAVSRLQTIAKEGNLPNIILTGLPGIGKTTSIMCLAHDLLGPSYKDAVLELNASDDRGIDVVRNRIKAFAQKKVTLPPGKHKIIVLDEADSMTGGAQQALRRTMEIYSNTTRFALACNQSNKIIEPIQSRCAVLRYNRLTDQQILHRLLEICEMEKVDYTDEGLEALIFTADGDMRQAVNNLQSTHYGFKHVNADNVFKICDQPHPVVIQHILKCCSEGNVDDAVNCLEQLYDAGYSALDIITTIFRVTRNYVEMSEQLRLDYLKEIGFTHMRILDGHQSIIQLSGMIAKLCHIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NFU6</accession>
    <name>A0A1C7NFU6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_05714</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000317">
        <property type="protein sequence ID" value="OBZ86234.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NFU6"/>
    <dbReference type="InParanoid" id="A0A1C7NFU6"/>
    <dbReference type="OrthoDB" id="2289328at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="50"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="50"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="87"/>
            <end position="104"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ86234.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="104" mass="11564" checksum="15DF0418EF0056CE" modified="2016-11-30" version="1">MDNVQHLEQIPDFVRIEAQRLSSSLNLFRIEPQNISYNITAGDFNVINTFNGEDPSPSTNSAESYDEEEDKIASDLSIHHPQRTCRLQSSSELGNGLGSLDTVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NFU9</accession>
    <name>A0A1C7NFU9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Elongation factor 2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">EFT2_0</name>
        <name evidence="10" type="ORF">A0J61_05705</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000316">
        <property type="protein sequence ID" value="OBZ86244.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="FunCoup" id="A0A1C7NFU9">
        <property type="interactions" value="559"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NFU9"/>
    <dbReference type="InParanoid" id="A0A1C7NFU9"/>
    <dbReference type="OrthoDB" id="364892at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043022">
        <property type="term" value="F:ribosome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01681">
        <property type="entry name" value="aeEF2_snRNP_like_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd04096">
        <property type="entry name" value="eEF2_snRNP_like_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01885">
        <property type="entry name" value="EF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd16261">
        <property type="entry name" value="EF2_snRNP_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.30.10:FF:000010">
        <property type="entry name" value="Translation elongation factor 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.230.10:FF:000006">
        <property type="entry name" value="Translation elongation factor 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.240:FF:000003">
        <property type="entry name" value="Translation elongation factor 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.870:FF:000002">
        <property type="entry name" value="Translation elongation factor 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000058">
        <property type="entry name" value="Translation elongation factor 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.870">
        <property type="entry name" value="Elongation Factor G (Translational Gtpase), domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.10">
        <property type="entry name" value="Translation factors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041095">
        <property type="entry name" value="EFG_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035647">
        <property type="entry name" value="EFG_III/V"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000640">
        <property type="entry name" value="EFG_V-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004161">
        <property type="entry name" value="EFTu-like_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031157">
        <property type="entry name" value="G_TR_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_Su5_D2-typ_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribsml_uS5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000795">
        <property type="entry name" value="T_Tr_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005517">
        <property type="entry name" value="Transl_elong_EFG/EF2_IV"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42908:SF10">
        <property type="entry name" value="EUKARYOTIC TRANSLATION ELONGATION FACTOR 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42908">
        <property type="entry name" value="TRANSLATION ELONGATION FACTOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00679">
        <property type="entry name" value="EFG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14492">
        <property type="entry name" value="EFG_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03764">
        <property type="entry name" value="EFG_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00009">
        <property type="entry name" value="GTP_EFTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03144">
        <property type="entry name" value="GTP_EFTU_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00315">
        <property type="entry name" value="ELONGATNFCT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00838">
        <property type="entry name" value="EFG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00889">
        <property type="entry name" value="EFG_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54980">
        <property type="entry name" value="EF-G C-terminal domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="Ribosomal protein S5 domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="Translation proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00301">
        <property type="entry name" value="G_TR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51722">
        <property type="entry name" value="G_TR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 10" id="KW-0251">Elongation factor</keyword>
    <keyword evidence="7" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tr-type G" evidence="9">
        <location>
            <begin position="18"/>
            <end position="349"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00017891"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022768"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00024731"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OBZ86244.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="845" mass="93460" checksum="F0CA2477FBC9BA39" modified="2016-11-30" version="1">MGNNFTIEEIRGLMDKVTNVRNMSVIAHVDHGKSTLTDSLVSKAGIISSGRAGEARFMDTRKDEQERGITIKSTAISMYFRMENEDDLKEIKNQKTDGPAFLINLIDSPGHVDFSSEVTAALRVTDGALVVVDCIDGVCVQTETVLRQALNERIKPVICLNKVDRALLELQLDKEELYNSFARTVESVNVIISTYVDEALGDCQVYPEKGTVAFASGLHGWGFTLRQFANRYAKKFGVDKNKMMVKLWGENYFNPKTKKWTTKSTDAEGKPLERAFNMFVLDPIYRLFDSIMNFKKEQTATLLEKLEVSLANDEKDLEGKALLKVVMRKFLPAGDALLEMICIHLPSPVTSQAYRCAQLYEGPSDDECAVGIRACDPNGPLMLYVSKMVPTSDKGRFYAFGRVFSGTVRAGMKVRIQGPNYVPGQKNDLAVKSIQRTVLMMGRNVEAIDDCPAGNIVGLVGVDQFLVKTGTITTSEVAHNMKVMKFSVSPVVQVAVEVKNANDLPKLVEGLKRLAKSDPCVXTFTSDSGEHXVAGAGELHLEICLKDLEEDHAQVPLKTGDPVVQYRETVTAESTIDCLSKSPNKHNRIYMRAAPLDDDLANEIEDGKISAKDDFKTRARVLADKYEWDVTEARKIWCFGPDGTGPNVMVDVTKQVQYLGEIKDSCVAAFQWATKEGPIAEEILRGCRFNILDVTLHADAIHRGGGQIIPTCRRVVYASVLTATPGIQEPVYLVEIQCPESAIGGIYSCLNRRRGTVFSEEQKAGTPMMTVKAHLPINESFGFTGDLRAATSGQAFPQAVFDHWSIMSGNPLEPGNKVYDMIRAVRTRKGLTPDIPGLDKYYDKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NGV2</accession>
    <name>A0A1C7NGV2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">PHO85 cyclin-like protein psl1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">psl1_3</name>
        <name evidence="2" type="ORF">A0J61_03683</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000163">
        <property type="protein sequence ID" value="OBZ88265.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NGV2"/>
    <dbReference type="FunCoup" id="A0A1C7NGV2">
        <property type="interactions" value="49"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NGV2"/>
    <dbReference type="InParanoid" id="A0A1C7NGV2"/>
    <dbReference type="OrthoDB" id="1060854at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000307">
        <property type="term" value="C:cyclin-dependent protein kinase holoenzyme complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016538">
        <property type="term" value="F:cyclin-dependent protein serine/threonine kinase regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019901">
        <property type="term" value="F:protein kinase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd20558">
        <property type="entry name" value="CYCLIN_ScPCL7-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.10">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013922">
        <property type="entry name" value="Cyclin_PHO80-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15615">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15615:SF94">
        <property type="entry name" value="PHO85 CYCLIN-6-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08613">
        <property type="entry name" value="Cyclin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="255"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="255"/>
            <end position="267"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ88265.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="274" mass="31352" checksum="80E823295684EBAF" modified="2016-11-30" version="1">MNDTENLHFDLATFPVKETIKLLTALLEKITRTNDQLQLESGLHKPSTYTCFHARSIPTISIHAYFTRILKYCPCANECLIALLVYFDRMTQPSPHLTPLHIDSYNIHRLIITGLMISSKLYSDVFFTNTRYAKVGGLPVGELNALELEFLRLNSYNLFVDIDKLQRYGDNVLELWSHSQDISALAIRETGNNHHSDNVIHEEIARPFSRLTMRTNDKCKMLPSGPESPTSPTSPLAESAFDRHWRYSRQSFSLRRNSTGNGATTDIHNTRNHM</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NH29</accession>
    <name>A0A1C7NH29_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Nitrogen regulatory protein areA GATA-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_03600</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000158">
        <property type="protein sequence ID" value="OBZ88345.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NH29"/>
    <dbReference type="STRING" id="101091.A0A1C7NH29"/>
    <dbReference type="InParanoid" id="A0A1C7NH29"/>
    <dbReference type="OrthoDB" id="5563539at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005773">
        <property type="term" value="C:vacuole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042149">
        <property type="term" value="P:cellular response to glucose starvation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007039">
        <property type="term" value="P:protein catabolic process in the vacuole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013860">
        <property type="entry name" value="AreA_GATA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052292">
        <property type="entry name" value="Glucose_repression_reg"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28051">
        <property type="entry name" value="PROTEIN MTL1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28051:SF1">
        <property type="entry name" value="PROTEIN MTL1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08550">
        <property type="entry name" value="GATA_AreA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nitrogen regulatory protein areA GATA-like" evidence="2">
        <location>
            <begin position="53"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="229"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="291"/>
            <end position="309"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF08550"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ88345.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="417" mass="46803" checksum="42F4CA89218EC591" modified="2016-11-30" version="1">MAPIVTAATVGSILKKPVAEDDFGSQQRRHVRQPEMCVDYLSYKFDEMDLAASWRVMTKQKKQVVDGIRLENASWRTWAKQRNNLKTISPQTLNWLKDSDVTWLYGPLHRVIQNGDEDPYLKPKKSTTADTLGLMLPIQTKQNQPPKLKSALKKKMTQVDLLRRSATELSLYSHTKTQRHHRTSSLSEVNQKLKAVSPAILATHRQPKLRFNTQVEQCIAVTVEEPTRDGCYGEDMYDSSSHSSSHSDQDTDEVMTSHIDHIPRQQTSSTIKKIAPARLKRSHSDQDTDDISSISSNSTSSSRVITQSSPICHYSSDSDTEEVVVEQKKPVYQSQLGRSSSTGSIVAYKEKSDVAQPALVKTHQTATDINKTTTTNQTGIFNHIATWASSYLWPGQKKAQLPTTLERSISSSIHHSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NHB5</accession>
    <name>A0A1C7NHB5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Cytochrome c oxidase assembly factor 3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">COA3</name>
        <name evidence="11" type="ORF">A0J61_03439</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 9">Required for assembly of cytochrome c oxidase (complex IV).</text>
    </comment>
    <comment type="subunit">
        <text evidence="4 9">Component of 250-400 kDa complexes called cytochrome oxidase assembly intermediates or COA complexes.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion membrane</location>
            <topology evidence="2">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 9">Belongs to the COA3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000148">
        <property type="protein sequence ID" value="OBZ88512.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NHB5"/>
    <dbReference type="STRING" id="101091.A0A1C7NHB5"/>
    <dbReference type="InParanoid" id="A0A1C7NHB5"/>
    <dbReference type="OrthoDB" id="10018333at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033617">
        <property type="term" value="P:mitochondrial respiratory chain complex IV assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041752">
        <property type="entry name" value="Coa3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018628">
        <property type="entry name" value="Coa3_CC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15642:SF3">
        <property type="entry name" value="CYTOCHROME C OXIDASE ASSEMBLY FACTOR 3 HOMOLOG, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15642">
        <property type="entry name" value="CYTOCHROME C OXIDASE ASSEMBLY FACTOR 3, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09813">
        <property type="entry name" value="Coa3_cc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 9" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="9" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="35"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="domain" description="Cytochrome c oxidase assembly factor 3 mitochondrial coiled-coil" evidence="10">
        <location>
            <begin position="22"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003064"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011351"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU367056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF09813"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="OBZ88512.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="77" mass="8683" checksum="E003A39A68503596" modified="2016-11-30" version="1">MENHPSREKLYSTSKGYGFSPALQRTRKPFAARNMLTLAGLITFTTSVYAYSLLAVKQDDFSDVPMPPPVNEQENKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NI32</accession>
    <name>A0A1C7NI32_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">MAP/microtubule affinity-regulating kinase 4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">MARK4</name>
        <name evidence="6" type="ORF">A0J61_03151</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000131">
        <property type="protein sequence ID" value="OBZ88793.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NI32"/>
    <dbReference type="STRING" id="101091.A0A1C7NI32"/>
    <dbReference type="InParanoid" id="A0A1C7NI32"/>
    <dbReference type="OrthoDB" id="504170at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035556">
        <property type="term" value="P:intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd14003">
        <property type="entry name" value="STKc_AMPK-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000042">
        <property type="entry name" value="Aurora kinase A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000571">
        <property type="entry name" value="Maternal embryonic leucine zipper kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24346">
        <property type="entry name" value="MAP/MICROTUBULE AFFINITY-REGULATING KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24346:SF110">
        <property type="entry name" value="NON-SPECIFIC SERINE_THREONINE PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0418">Kinase</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="5">
        <location>
            <begin position="39"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="296"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="355"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="578"/>
            <end position="635"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="687"/>
            <end position="713"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="773"/>
            <end position="792"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="810"/>
            <end position="906"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="307"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="370"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="597"/>
            <end position="616"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="69"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OBZ88793.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="906" mass="100936" checksum="B1B95293718AE9BF" modified="2016-11-30" version="1">MISSPRNSVAHNQQAKLAVDYNELLKELSSHEMTSVGCYTIGETIGEGTFGKVKKGTHKLTGKLVAIKKISKQHAPMMAREIHHHRQLKHPNIVMLYEMITTESAIHIISEYCPSGDLLDALTDAGRCSEIRVHKWFRQLADAIHYCHLRGIVHRDLKLENILLDSEDNVKICDFGFARFTQKNQYLETFCGSLSYSAPEVIMRKKYTGPETDIWSLGVILYTLIAGEYPFDDDSEVMTQRKIVQVDYTIPFYFSTDLNSLITNMLQFNPCDRISFEAMETHPWVVRLDHLIDDDGEDEEDEDTCLTPSSSTTTHQSTASDVDSIFSQNESTVALDDGIDYNTLSPDLKFSPQVRSSLGISKPQAAPKSSRFSAPTFNRRTPQPTSFRSSLPSSFYQSNAEQPAMTPVEQRLFAALTAAGFDRDALIKMQTGECDTSSTLWHLLLENMSNQPQPAWQNFSVPDAFASAMQQHRIPTTVDTHPKKAVDQGTQTFQEGEEEEEQKEEQENKFICQQKDTNDQLKTDTVLFNTIEPAVQPYPKPTVSIPYHSIPTVGFGSPQPTPERAGWFSSVKSWFGSKPPPSTASSISPSPQRRGRSASTCSTMSSPIATPSSYRNFDTPVDHSVDTNMMSPPIYRTGSQKYRRRVLQLSDPPVCELDQLTYNGTTAIPAAPAPNTTNSPITITHPKHNTNNTTTSNTHTTSITKSSHTTTSNSAFHTQNAFNYRTPSSLDMPPVALTSTRLATDTFSILTTESSEPKEIDICQRRYSLLYSQRQQHHPTPPSSPPALDQHCSEMPSMVLSEENHVEMPLNAGEGKEPLSDFSSDSSTSEEDEEMVVSTPAETVAPQPPLTSSFALKMASTGGGRPRNPRFEFTPRSRLTVYGMQEQKGPSFGSKAIIEEEEEEEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NI57</accession>
    <name>A0A1C7NI57_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">D-serine dehydratase</fullName>
            <ecNumber evidence="11">4.3.1.18</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13">D-serine deaminase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">A0J61_03282</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Catalyzes the conversion of D-serine to pyruvate and ammonia. May play a role in D-serine detoxification.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>D-serine = pyruvate + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:13977"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:35247"/>
            <dbReference type="EC" id="4.3.1.18"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="9">
            <dbReference type="Rhea" id="RHEA:13978"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the DSD1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.3.1.18" evidence="11"/>
    <dbReference type="EMBL" id="LUGH01000138">
        <property type="protein sequence ID" value="OBZ88680.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NI57"/>
    <dbReference type="FunCoup" id="A0A1C7NI57">
        <property type="interactions" value="34"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NI57"/>
    <dbReference type="InParanoid" id="A0A1C7NI57"/>
    <dbReference type="OrthoDB" id="20198at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008721">
        <property type="term" value="F:D-serine ammonia-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036088">
        <property type="term" value="P:D-serine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009636">
        <property type="term" value="P:response to toxic substance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.10:FF:000016">
        <property type="entry name" value="D-serine dehydratase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.10">
        <property type="entry name" value="Alanine racemase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.37.20">
        <property type="entry name" value="D-serine dehydratase-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001608">
        <property type="entry name" value="Ala_racemase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051466">
        <property type="entry name" value="D-amino_acid_metab_enzyme"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026956">
        <property type="entry name" value="D-ser_dehydrat-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042208">
        <property type="entry name" value="D-ser_dehydrat-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029066">
        <property type="entry name" value="PLP-binding_barrel"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28004:SF2">
        <property type="entry name" value="D-SERINE DEHYDRATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28004">
        <property type="entry name" value="ZGC:162816-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01168">
        <property type="entry name" value="Ala_racemase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14031">
        <property type="entry name" value="D-ser_dehydrat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01119">
        <property type="entry name" value="D-ser_dehydrat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51419">
        <property type="entry name" value="PLP-binding barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0216">Detoxification</keyword>
    <keyword evidence="8" id="KW-0456">Lyase</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="D-serine dehydratase-like" evidence="14">
        <location>
            <begin position="307"/>
            <end position="414"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005323"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022575"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00051198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00055764"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00066349"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00069616"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00075219"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="SMART" id="SM01119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="OBZ88680.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="429" mass="47859" checksum="C7F7F9143F47E803" modified="2016-11-30" version="1">MMVQTKTHVTPIAFNQQWKATLAKDYIGKKLTELRTPSLVISRTVLQRNSERLREITTKFGLRVRIHVKTHKTTEGAQIQLKGVTSDAIVVSTLPEAHSMVDSDLVKEGLLKEVLVGFPITADKLEDVFELSKRIHKLQIFVDNLNTLEDIEAYLKTKPDGKKHQHHIHVFLKADCGYGRAGALIDNATTIELAKRLQDSPYLTFEGIYTHAGHSYSSESPQDALEYLKNECNFARQFRDFLQKNGVRICCISIGATPTVKAITVFMDQQEQMRDILKDIDEVHAGAFGFLDRQQVATGLGSLKDVSISVAVRIASVYPDQRKILVDGGALAFSKDTAPQGGFGYVVDMNDRDCLGNPKVIASVTKVAQEHGLLQDVDEAVFKRLDFQIGSVLRVIPNHCCLTAACHPFYLIVEDDDTVVDVWVPVRGW</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NID0</accession>
    <name>A0A1C7NID0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_03049</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000125">
        <property type="protein sequence ID" value="OBZ88883.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NID0"/>
    <dbReference type="InParanoid" id="A0A1C7NID0"/>
    <dbReference type="OrthoDB" id="2402731at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="154"/>
            <end position="176"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ88883.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="176" mass="20147" checksum="0FD48A419B3997E4" modified="2016-11-30" version="1">MVHNSSKSISVSDRAFVEFCRCLYQAKAVVRELESFSNSVCPILNSHPELIQKEEKGEMTRFGNGLLLEQVNKYLNTTFRKFTRLCRILMVVLTQIETSSAGKVKKERIDSFRVEVWEEWKTATSIKQRLIHFTQQSKKDKTVYTTTTTTMTTLDDPPSTTTTTTTTTTTTTTTLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NIU1</accession>
    <name>A0A1C7NIU1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_04725</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000237">
        <property type="protein sequence ID" value="OBZ87234.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NIU1"/>
    <dbReference type="InParanoid" id="A0A1C7NIU1"/>
    <dbReference type="OrthoDB" id="2277867at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ87234.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="97" mass="10881" checksum="98B151E099603E15" modified="2016-11-30" version="1">MDIRYRVQAMGMIKIWSANTHLIHLDTNTTIDSFPHLKWTTNKRKSVNDTVHATWSIPPTLPSGNYSMNITANGTSLCSKNNNGSAPFVRCRYSLGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NIV7</accession>
    <name>A0A1C7NIV7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Stress-associated endoplasmic reticulum protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">A0J61_03025</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Interacts with target proteins during translocation into the lumen of the endoplasmic reticulum. Protects unfolded target proteins against degradation and facilitate correct glycosylation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Membrane</location>
            <topology evidence="6">Single-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="6">Endoplasmic reticulum membrane</location>
            <topology evidence="6">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the RAMP4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000123">
        <property type="protein sequence ID" value="OBZ88938.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NIV7"/>
    <dbReference type="STRING" id="101091.A0A1C7NIV7"/>
    <dbReference type="InParanoid" id="A0A1C7NIV7"/>
    <dbReference type="OrthoDB" id="16679at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010580">
        <property type="entry name" value="ER_stress-assoc"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06624">
        <property type="entry name" value="RAMP4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="39"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005500"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU364120"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OBZ88938.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="64" mass="7029" checksum="F65DF45DB6538130" modified="2016-11-30" version="1">MATTPALRQKNEIYNKRSKNGAVAVKATEKSKQVRKSNLSYAAFGILAFALFGGLLLQLIDLLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-06-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NJS2</accession>
    <name>A0A1C7NJS2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_02569</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000098">
        <property type="protein sequence ID" value="OBZ89393.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NJS2"/>
    <dbReference type="InParanoid" id="A0A1C7NJS2"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ89393.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="130" mass="14642" checksum="D988C68A42311DF3" modified="2016-11-30" version="1">MLLEISDFRDLSQNCFVRQGTVFDKSGRELGSSVCIKQQTFEQSTLTIVSLQDLMDAVVLHVDYIIIDIKAHFIQLGIIKLASAFAFPAIERMSRCSNINGIIFVSTVYHVAQARKEKSIACIEASWIRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NJT7</accession>
    <name>A0A1C7NJT7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">phosphatidate cytidylyltransferase</fullName>
            <ecNumber evidence="6">2.7.7.41</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="16">CDP-diacylglycerol synthase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="17">CDP-diglyceride pyrophosphorylase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="18">CDP-diglyceride synthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="20" type="primary">CDS2</name>
        <name evidence="20" type="ORF">A0J61_02701</name>
    </gene>
    <organism evidence="20 21">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="20 21" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="20 21">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 22 23">
            <text>a 1,2-diacyl-sn-glycero-3-phosphate + CTP + H(+) = a CDP-1,2-diacyl-sn-glycerol + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:16229"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:37563"/>
            <dbReference type="ChEBI" id="CHEBI:58332"/>
            <dbReference type="ChEBI" id="CHEBI:58608"/>
            <dbReference type="EC" id="2.7.7.41"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="4">Lipid metabolism.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3">Phospholipid metabolism; CDP-diacylglycerol biosynthesis; CDP-diacylglycerol from sn-glycerol 3-phosphate: step 3/3.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the CDS family.</text>
    </comment>
    <comment type="caution">
        <text evidence="20">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.41" evidence="6"/>
    <dbReference type="EMBL" id="LUGH01000105">
        <property type="protein sequence ID" value="OBZ89258.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NJT7"/>
    <dbReference type="STRING" id="101091.A0A1C7NJT7"/>
    <dbReference type="InParanoid" id="A0A1C7NJT7"/>
    <dbReference type="OrthoDB" id="10260889at2759"/>
    <dbReference type="UniPathway" id="UPA00557">
        <property type="reaction ID" value="UER00614"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004605">
        <property type="term" value="F:phosphatidate cytidylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016024">
        <property type="term" value="P:CDP-diacylglycerol biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016720">
        <property type="entry name" value="PC_Trfase_euk"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13773">
        <property type="entry name" value="PHOSPHATIDATE CYTIDYLYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13773:SF8">
        <property type="entry name" value="PHOSPHATIDATE CYTIDYLYLTRANSFERASE, PHOTORECEPTOR-SPECIFIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01148">
        <property type="entry name" value="CTP_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="12" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="13 19" id="KW-0472">Membrane</keyword>
    <keyword evidence="10 20" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="14" id="KW-0594">Phospholipid biosynthesis</keyword>
    <keyword evidence="15" id="KW-1208">Phospholipid metabolism</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 20" id="KW-0808">Transferase</keyword>
    <keyword evidence="9 19" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="11 19" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="82"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="123"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="146"/>
            <end position="166"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001698"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00010185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00012487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00029893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00032396"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00033406"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="OBZ89258.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="212" mass="23752" checksum="70ACFA81AB45D7A1" modified="2016-11-30" version="1">MIGMSREEPLEQTYECSFVSRTYRALFATCALRFCNWVLSVLNQCPPDSLGSHVLHVSWVHLCVLYTVPQPILIYHNIDQGGIFWFLFPSMLVVCNDIAAYVCGRRFGKTKLVSLSPNKTLEGFIGALVVTVLWAFIAELDVCIRFHAVMMALFASLISPFGGFFASAVKRASGLKDFDEFIPGHGGLSDRVDCQLFMAMFTFAYYHSFIAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NJV8</accession>
    <name>A0A1C7NJV8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">CAP-Gly domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">A0J61_02688</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
            <location evidence="1">Spindle</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000104">
        <property type="protein sequence ID" value="OBZ89278.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NJV8"/>
    <dbReference type="InParanoid" id="A0A1C7NJV8"/>
    <dbReference type="OrthoDB" id="2130750at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030286">
        <property type="term" value="C:dynein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005819">
        <property type="term" value="C:spindle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.190">
        <property type="entry name" value="CAP Gly-rich-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.60.10">
        <property type="entry name" value="Zinc finger, CCHC-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036859">
        <property type="entry name" value="CAP-Gly_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000938">
        <property type="entry name" value="CAP-Gly_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032108">
        <property type="entry name" value="CLIP1_ZNF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18916">
        <property type="entry name" value="DYNACTIN 1-RELATED MICROTUBULE-BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18916:SF6">
        <property type="entry name" value="DYNACTIN SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01302">
        <property type="entry name" value="CAP_GLY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16641">
        <property type="entry name" value="CLIP1_ZNF"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM01052">
        <property type="entry name" value="CAP_GLY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74924">
        <property type="entry name" value="Cap-Gly domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00845">
        <property type="entry name" value="CAP_GLY_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50245">
        <property type="entry name" value="CAP_GLY_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6 8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="5" id="KW-0243">Dynein</keyword>
    <keyword evidence="3" id="KW-0493">Microtubule</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="CAP-Gly" evidence="10">
        <location>
            <begin position="154"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="98"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="233"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="359"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="593"/>
            <end position="652"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="718"/>
            <end position="829"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="100"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="235"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="255"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="296"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="341"/>
            <end position="351"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="OBZ89278.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="952" mass="109016" checksum="18364932076A0AC2" modified="2016-11-30" version="1">MANLDKQSYKCITKRNKTVDSTLFVSPSTKTNKSGCSTTIPAECITESLIRQQAKHSDQLEQTCRDIPEAATKILSSSSNASRSSTTNRYSGIIKRFSSQHKESDIPKPRSVLKKPEVEPSSTCDNEINQKVLVTHLNLTGTVRYIGEIGLMRKKGQWIGIELDIKGRGKNNGCLQGTRYFTCAPNTGLFVPSTKVARIDSDINRPITKPLVTFNKLDSESFKRKSMYTSSVMISNDDNNRSSNIPTDKHKLTKPTRTQSVKRSGNQSPHTLESDSSQPKKISTQKSSTSVHRRTLSSTSTARLSKQPPMRKSSSLSTKRVHDVTAACNTKTQQQRRHNNKQWLQSSVSSKTEAELDELKRMQVLLEQSREEKKALSEKIDTKEAAWERLLTAKESYALRVQEKDSEIARLNATLEKTHDAAEQLNDVIKERDTALSRLSMLNDTEKELSKTIERLGGHIQCLQQQNSDQANSHEMVLRSHASQMEQLRKQLIERDQTVTTVERECTDLRLMNAGIISAYESKIAQLTKDNELAMIERELHIDKLQQVVNNLHQIYPASNTSFVMDVEEEADTNIPTPQKQLXYQLELTTYELECEREQVKSMALDIDQLKEEIKRLHRLSATTDSEFYALRGQLEEEIVDKRRIMEEANATMENQTKVEEEKESLRITLIKTQFELAETLKKIAVNEKHRTKTDEIHWLIEKKRLLEVENEATSSSHLKLQDKCQQLKDKLTLYEHKSKKDQNCNTKEHVCQEKIRMLELQIAQEARRHRNLECSKQLKIDTLSREIKELETLIENKVFKESELEGLIEEKEMSIKILNIRLESEEEKNLKQSFGNSRSHSYSIPPLSPTSPQHFFIDQKRKPFHSTPSDSSESISNHGNLEEDVYCEICEEYGHEVITCRAVTIYDVLEKEENFITNAQLSAARSSFYCVNCDVFGEHPSEDCPNQDETF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NK88</accession>
    <name>A0A1C7NK88_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Vacuolar amino acid transporter 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">AVT2_1</name>
        <name evidence="10" type="ORF">A0J61_02475</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the amino acid/polyamine transporter 2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000094">
        <property type="protein sequence ID" value="OBZ89465.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NK88"/>
    <dbReference type="STRING" id="101091.A0A1C7NK88"/>
    <dbReference type="InParanoid" id="A0A1C7NK88"/>
    <dbReference type="OrthoDB" id="28208at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015179">
        <property type="term" value="F:L-amino acid transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013057">
        <property type="entry name" value="AA_transpt_TM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22950">
        <property type="entry name" value="AMINO ACID TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22950:SF458">
        <property type="entry name" value="SODIUM-COUPLED NEUTRAL AMINO ACID TRANSPORTER 11-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01490">
        <property type="entry name" value="Aa_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0029">Amino-acid transport</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="53"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="77"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="117"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="148"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="192"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="236"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="262"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="337"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="domain" description="Amino acid transporter transmembrane" evidence="9">
        <location>
            <begin position="5"/>
            <end position="286"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008066"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OBZ89465.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="359" mass="39487" checksum="D6FD26B69B46E4B3" modified="2016-11-30" version="1">MEYSFGRFGYHFLNFLILIQATGACVSYFILIGDTIPILLALYFPDYPSMTERSFVISFIAIVLVFPLNLSRSIGAVAKWSIISVLCLPIILLTLLIRAPAYSAAHEAPLNWQGPDIFGALGILAFAFSCSHVCFSVFLSLSDQTSRAWTITTSLASVMSWIASISFALIGYLCFGQDVQPNLFLNFPADDAIVNVGRFALGFSMILTIPMVFYPFREAVQKMIGFEITNKQPTAVQHYAVTVVLFVFLTGLGIYIRSLGKVYGFIGGFAATFLAYILPASACLITRRYPAVLPDMVSSVTTPSEDDDVVLIEQDEEVNGLKDEIESEAVPFGMLDFAAIFLIIWGFVVMVFATAGVFR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NKA8</accession>
    <name>A0A1C7NKA8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 16 17">Phosphatidate cytidylyltransferase</fullName>
            <ecNumber evidence="6 16 17">2.7.7.41</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">A0J61_04229</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18 19">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 16 17">
            <text>a 1,2-diacyl-sn-glycero-3-phosphate + CTP + H(+) = a CDP-1,2-diacyl-sn-glycerol + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:16229"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:37563"/>
            <dbReference type="ChEBI" id="CHEBI:58332"/>
            <dbReference type="ChEBI" id="CHEBI:58608"/>
            <dbReference type="EC" id="2.7.7.41"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="4">Lipid metabolism.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3 16 17">Phospholipid metabolism; CDP-diacylglycerol biosynthesis; CDP-diacylglycerol from sn-glycerol 3-phosphate: step 3/3.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5 16 17">Belongs to the CDS family.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.41" evidence="6 16 17"/>
    <dbReference type="EMBL" id="LUGH01000202">
        <property type="protein sequence ID" value="OBZ87724.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NKA8"/>
    <dbReference type="FunCoup" id="A0A1C7NKA8">
        <property type="interactions" value="544"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NKA8"/>
    <dbReference type="InParanoid" id="A0A1C7NKA8"/>
    <dbReference type="OrthoDB" id="10260889at2759"/>
    <dbReference type="UniPathway" id="UPA00557">
        <property type="reaction ID" value="UER00614"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004605">
        <property type="term" value="F:phosphatidate cytidylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016024">
        <property type="term" value="P:CDP-diacylglycerol biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000374">
        <property type="entry name" value="PC_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016720">
        <property type="entry name" value="PC_Trfase_euk"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13773">
        <property type="entry name" value="PHOSPHATIDATE CYTIDYLYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13773:SF8">
        <property type="entry name" value="PHOSPHATIDATE CYTIDYLYLTRANSFERASE, PHOTORECEPTOR-SPECIFIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01148">
        <property type="entry name" value="CTP_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF018269">
        <property type="entry name" value="PC_trans_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01315">
        <property type="entry name" value="CDS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 16" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="12 16" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="13 16" id="KW-0472">Membrane</keyword>
    <keyword evidence="10 16 17" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="14 16" id="KW-0594">Phospholipid biosynthesis</keyword>
    <keyword evidence="15 16" id="KW-1208">Phospholipid metabolism</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 16 17" id="KW-0808">Transferase</keyword>
    <keyword evidence="9 16 17" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="11 16" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="46"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="69"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="106"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="144"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="173"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="197"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="235"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="310"/>
            <end position="332"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001698"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00010185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00012487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PIRNR" id="PIRNR018269"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="RuleBase" id="RU003938"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="OBZ87724.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="434" mass="49427" checksum="DB49ECBED7A63508" modified="2016-11-30" version="1">MPPKFKKATKHRKPSFAEEVGKVEQMKEEAVTLLAAETSSKKWQNWWIRTVTTLIMIASFFAILASGYIWSIVMVMVITVLVYREVIHIAYHSAKGNLRWFKTMSWYYLITTEYFLYGESIIHYFKEIVLVDAFLLPFATHHRFISFILYVIGFVFFVVNLEKGQYRSQMSQFGWTHMAIFLIVFQAHFIVDNILEGLIWFVLPAALVVCNDIFAYICGFFYGKTPLIQLSPKKTVEGFVGGLIFTLIFGFLIATILMQFDYMICPVQDLGASAWSNISCEPKNPVFIATPWELPSLIQKDITEVWIAPVQLHAIVMAGFASLIAPFGGFFASAVKRAFKIKDFGHSIPGHGGLTDRMDCQFLMGLFAYMYYQSFIKMYKVTVGTILALAINSLSAKEQLELLERLQTYLANQDHLSSQIDTVISKAQHLLAGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NKB0</accession>
    <name>A0A1C7NKB0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Glia maturation factor gamma</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">GMFG</name>
        <name evidence="6" type="ORF">A0J61_02365</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="4">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the actin-binding proteins ADF family. GMF subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000088">
        <property type="protein sequence ID" value="OBZ89583.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NKB0"/>
    <dbReference type="FunCoup" id="A0A1C7NKB0">
        <property type="interactions" value="109"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NKB0"/>
    <dbReference type="InParanoid" id="A0A1C7NKB0"/>
    <dbReference type="OrthoDB" id="3919494at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030479">
        <property type="term" value="C:actin cortical patch"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003779">
        <property type="term" value="F:actin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071933">
        <property type="term" value="F:Arp2/3 complex binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071846">
        <property type="term" value="P:actin filament debranching"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034316">
        <property type="term" value="P:negative regulation of Arp2/3 complex-mediated actin nucleation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd11283">
        <property type="entry name" value="ADF_GMF-beta_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.20.10:FF:000026">
        <property type="entry name" value="Glia maturation factor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.20.10">
        <property type="entry name" value="Severin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002108">
        <property type="entry name" value="ADF-H"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029006">
        <property type="entry name" value="ADF-H/Gelsolin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011171">
        <property type="entry name" value="GMF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11249:SF2">
        <property type="entry name" value="GLIA MATURATION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11249">
        <property type="entry name" value="GLIAL FACTOR NATURATION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00241">
        <property type="entry name" value="Cofilin_ADF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001788">
        <property type="entry name" value="GMF-beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00102">
        <property type="entry name" value="ADF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55753">
        <property type="entry name" value="Actin depolymerizing proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51263">
        <property type="entry name" value="ADF_H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ADF-H" evidence="5">
        <location>
            <begin position="3"/>
            <end position="137"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRNR" id="PIRNR001788"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51263"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OBZ89583.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="137" mass="15927" checksum="B337ADED31F35FE3" modified="2016-11-30" version="1">MTSTCEIDPELVEKINQFRFAKYKSGNAAFVLQIDRKTLKIVEEEVYENTPIEELVEELPENTPRFVILSYELKYSDGRVNFPLLFIYWSPSTAKAEINMLYASAKTYLQEKIGVNRGFDIRDAETLTDEFLTKQLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NKI9</accession>
    <name>A0A1C7NKI9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_02953</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000119">
        <property type="protein sequence ID" value="OBZ89006.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NKI9"/>
    <dbReference type="STRING" id="101091.A0A1C7NKI9"/>
    <dbReference type="InParanoid" id="A0A1C7NKI9"/>
    <dbReference type="OrthoDB" id="2401996at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="122"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="300"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="131"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="334"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="390"/>
            <end position="412"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ89006.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="451" mass="49902" checksum="A41885DE2B535502" modified="2016-11-30" version="1">MMDLTYDTSPLTNSVKHTSETSHPIGGDAVHMLLAKLDEGTQTVINLRSILTLKTAELNELLAQLELTNQAITNVESTTNQIEHMLRDFGISDPTKESLLIDAEASLDSAIKSAASIYPQQFKQKLRRRPSTTSTNSGSAMESVEGKRMSNARLLNTRIRYKPDTKHILRKLNDLLRDLDMDSGKFFATIGTTDDFEVLQKAYVDLDIAKTISLSAKSNMKRRNILIRSARRRNNKEEIEALGDKIREGVALWLNYTRNTPLMIKGEDILTILEREDTLLAKNLPISQLDTIQTDSSNVKRSISNETKRSSFIRPTSIITPPPPPPIEKPAVEKPPATKTTTVPTKKPIRPSTGPRLTQVKASIGLPRVRTTSITQPTPKESKTPPKEPSTPLINTRPTHIPLPTHPTTTPPDNSKKSALKTPSQRGPGSTLRLRSMLAKRGTPSQAAKPT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NLE3</accession>
    <name>A0A1C7NLE3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 13">Aconitate hydratase, mitochondrial</fullName>
            <shortName evidence="13">Aconitase</shortName>
            <ecNumber evidence="13">4.2.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="primary">acoA</name>
        <name evidence="16" type="ORF">A0J61_01960</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12 18">
            <text>citrate = D-threo-isocitrate</text>
            <dbReference type="Rhea" id="RHEA:10336"/>
            <dbReference type="ChEBI" id="CHEBI:15562"/>
            <dbReference type="ChEBI" id="CHEBI:16947"/>
            <dbReference type="EC" id="4.2.1.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="13">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="13">Binds 1 [4Fe-4S] cluster per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2">Carbohydrate metabolism; tricarboxylic acid cycle; isocitrate from oxaloacetate: step 2/2.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 13">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 13">Belongs to the aconitase/IPM isomerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.-" evidence="13"/>
    <dbReference type="EMBL" id="LUGH01000069">
        <property type="protein sequence ID" value="OBZ89981.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NLE3"/>
    <dbReference type="FunCoup" id="A0A1C7NLE3">
        <property type="interactions" value="639"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NLE3"/>
    <dbReference type="InParanoid" id="A0A1C7NLE3"/>
    <dbReference type="OrthoDB" id="2224430at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042645">
        <property type="term" value="C:mitochondrial nucleoid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003994">
        <property type="term" value="F:aconitate hydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003690">
        <property type="term" value="F:double-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01584">
        <property type="entry name" value="AcnA_Mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.19.10:FF:000002">
        <property type="entry name" value="Aconitate hydratase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.499.10:FF:000003">
        <property type="entry name" value="Aconitate hydratase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.499.10:FF:000004">
        <property type="entry name" value="Aconitate hydratase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.1060.10:FF:000001">
        <property type="entry name" value="Aconitate hydratase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1060.10">
        <property type="entry name" value="Aconitase, Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.499.10">
        <property type="entry name" value="Aconitase, domain 3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.19.10">
        <property type="entry name" value="Aconitase, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015931">
        <property type="entry name" value="Acnase/IPM_dHydase_lsu_aba_1/3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001030">
        <property type="entry name" value="Acoase/IPM_deHydtase_lsu_aba"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015928">
        <property type="entry name" value="Aconitase/3IPM_dehydase_swvl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050926">
        <property type="entry name" value="Aconitase/IPM_isomerase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018136">
        <property type="entry name" value="Aconitase_4Fe-4S_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036008">
        <property type="entry name" value="Aconitase_4Fe-4S_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015932">
        <property type="entry name" value="Aconitase_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006248">
        <property type="entry name" value="Aconitase_mito-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000573">
        <property type="entry name" value="AconitaseA/IPMdHydase_ssu_swvl"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01340">
        <property type="entry name" value="aconitase_mito"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF005558">
        <property type="entry name" value="PRK07229.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43160">
        <property type="entry name" value="ACONITATE HYDRATASE B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43160:SF3">
        <property type="entry name" value="ACONITATE HYDRATASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00330">
        <property type="entry name" value="Aconitase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00694">
        <property type="entry name" value="Aconitase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00415">
        <property type="entry name" value="ACONITASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53732">
        <property type="entry name" value="Aconitase iron-sulfur domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52016">
        <property type="entry name" value="LeuD/IlvD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00450">
        <property type="entry name" value="ACONITASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01244">
        <property type="entry name" value="ACONITASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 13" id="KW-0408">Iron</keyword>
    <keyword evidence="9 13" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="11 13" id="KW-0456">Lyase</keyword>
    <keyword evidence="6 13" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10 13" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 13" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="5" id="KW-0816">Tricarboxylic acid cycle</keyword>
    <feature type="domain" description="Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha" evidence="14">
        <location>
            <begin position="74"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="domain" description="Aconitase A/isopropylmalate dehydratase small subunit swivel" evidence="15">
        <location>
            <begin position="590"/>
            <end position="717"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004717"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00015940"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU362107"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF00330"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF00694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="OBZ89981.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="787" mass="85611" checksum="10FE6B7640070C18" modified="2016-11-30" version="1">MLSSNNFLRAAKAFAPAIRTHVPARTYAQAGTNWAAQKVAMSNLEQDKFINYQRIEDNLQIVRKRLNRPLTLSEKVVYGHLDDAENQDIVRGQSYLKLRPDRVACQDATAQMALLQFMSAGLPNVAVPSTVHCDHLIEAQVGGPKDLARAIDINKEVYDFLATATAKYGLGFWKPGSGIIHQIILENYAFPGGLMIGTDSHTPNAGGLGMVAIGVGGADAVDVMADIPWELKCPKVIGVKLNGKLNGWTSPKDIILKVAGILTVKGGTGAIVEYFGEGVNSFSCTGMATICNMGAEIGATTSMFPFNERMGDYLRATNRSAIADYAKAFSHNLRADENAQYDEVIEIDLDTLEPHINGPFTPDLATPLSKFKETAIKNDWPQELKVGLIGSCTNSSYEDMTRSASLIKQANEHGVKLKSKYTVTPGSEQIRATIERDGIMDTFTNAGGVVLANACGPCIGQWDRQDIKKGDKNSIITSYNRNFTGRNDANPQTHAFVASPEIVTALAIAGDMHFNPMTDSLVGADGNPFKLDPPSGEALPARGYDAGENTYQAPPSDRSSVNVAVDPKSNRLQLLEPFEKWNGKDITEVPILIKAKGKCTTDHISMAGPWLKYRGHLDNISNNFLIGATSNEGNVNNVKNAFTGEYGAVPDVARDYKARGIKWVVFGDENYGEGSSREHAALEPRFLNGAAVITKSFARIHETNLKKQGMLPLTFANPADYDLVETDDKVSILGLTDFQPGKQLTVRLTKKDGSSKDIPVNHTFNEGQIKWFKYGSALNLMKEQAAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NLX0</accession>
    <name>A0A1C7NLX0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Putative aminotransferase C6B12.04c</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">A0J61_02504</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000095">
        <property type="protein sequence ID" value="OBZ89446.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NLX0"/>
    <dbReference type="FunCoup" id="A0A1C7NLX0">
        <property type="interactions" value="305"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NLX0"/>
    <dbReference type="InParanoid" id="A0A1C7NLX0"/>
    <dbReference type="OrthoDB" id="2414662at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047536">
        <property type="term" value="F:2-aminoadipate transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016212">
        <property type="term" value="F:kynurenine-oxoglutarate transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034276">
        <property type="term" value="P:kynurenic acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd00609">
        <property type="entry name" value="AAT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.640.10:FF:000024">
        <property type="entry name" value="Kynurenine--oxoglutarate transaminase 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004839">
        <property type="entry name" value="Aminotransferase_I/II_large"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051326">
        <property type="entry name" value="Kynurenine-oxoglutarate_AT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004838">
        <property type="entry name" value="NHTrfase_class1_PyrdxlP-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43807">
        <property type="entry name" value="FI04487P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43807:SF20">
        <property type="entry name" value="FI04487P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00155">
        <property type="entry name" value="Aminotran_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00105">
        <property type="entry name" value="AA_TRANSFER_CLASS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="5" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotransferase class I/classII large" evidence="6">
        <location>
            <begin position="31"/>
            <end position="414"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OBZ89446.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="422" mass="47501" checksum="8630652A8666B4AB" modified="2016-11-30" version="1">MSPPQIKPAERVSHFGRDVWSIFTPLALETKAINLGQGFMNFAPPSVVQAAAKEALETVEANHYSHPKGRIRLRQAIAASYGKELNRELDPETEILVSAGANEGMFATFAGFLDDGDEVICMEPFFDQYIPNITMNGGKPVYVPLRPPSDASDRVVSSHEWKLDVNELRSKITSRTKIIVVNTPHNPVGKVFDEDELRAIGQVAEEHNLIILSDEVYDRLYYPPLNKFPRIATLDNFWQRTITVGSAGKSFAATGWRVGWLIGPEHLIKHVFAAQTRVIFCVNSPCQEAVASGLEASLTQPIFQEQIDAYLKKRSILSKVFDELGLSYTVPEGSYFILVNTSKIQIPKDFEFPDILNDRGDDFKTCYWLTKHIGVCAIPPSEFYAKDHWHMAANFARFAFCKTDEVLEQAAERLREIKKYIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NN39</accession>
    <name>A0A1C7NN39_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_01436</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000045">
        <property type="protein sequence ID" value="OBZ90533.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NN39"/>
    <dbReference type="InParanoid" id="A0A1C7NN39"/>
    <dbReference type="OrthoDB" id="10404951at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="104"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="20"/>
            <end position="35"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ90533.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="223" mass="25605" checksum="F5E58405CEDF18D3" modified="2016-11-30" version="1">MSDKENNVPLDSIKKDTKISNKTTLPTESTHTINQDDSEVSVEKARRSAAPGLADTPWHLQEDSVELARPSKTALRETPIQKKSGYINVHHKQLDATAIKSTDQTQQEELLEQEIKKIQKLNADKTKQLLALKDQIKQKRKELDELESTLSQVTVAQDNISRINTEIEEHKEMFVELSGMLKEVDETWSGYQQSIEEKEQCIEERLNQLSTVKYHILELEEQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NN69</accession>
    <name>A0A1C7NN69_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="1">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">oca2_1</name>
        <name evidence="11" type="ORF">A0J61_01367</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="1"/>
    <dbReference type="EMBL" id="LUGH01000042">
        <property type="protein sequence ID" value="OBZ90582.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NN69"/>
    <dbReference type="STRING" id="101091.A0A1C7NN69"/>
    <dbReference type="InParanoid" id="A0A1C7NN69"/>
    <dbReference type="OrthoDB" id="6513151at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24343">
        <property type="entry name" value="SERINE/THREONINE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24343:SF137">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE HRK1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 11" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="10">
        <location>
            <begin position="1"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="45"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="102"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="323"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="56"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="115"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="336"/>
            <end position="345"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="OBZ90582.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="345" mass="39349" checksum="998EF1888320994C" modified="2016-11-30" version="1">MPPSPALSPAVVTHTNATTRHLHTNDSAAVDYYELTKLLQNVVASKNPRRPSIQQTASPTSTSNSTTSSVSSSTSTSSRHTNMPSQFVFKKPLYNQHYHQTHFHHHAPPSPPSSISPTHTHHSQTPDQRNKDLFLAWSDLRRFFAHQQSPLSPVSPTLETEEQSFANQFKHNISGRYGQWGVFGSDPYIAPEQYVQPMYDPRLSDVWSCGIIFVCMTIRRFPWRLPRNSDPAFRAFATNYNQQKFRLLKLLPRESRSVMTSILEVDPNRRWSLQNILKDSWINSIDVCTVHEPGARHIHHVSVLDPAIQQERGNLVTMTLEPPGVIAEKEKRKRQLQQSPQKKPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NN83</accession>
    <name>A0A1C7NN83_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">V-type proton ATPase subunit H</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">VATH_1</name>
        <name evidence="7" type="ORF">A0J61_01359</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the V-ATPase H subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000042">
        <property type="protein sequence ID" value="OBZ90591.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NN83"/>
    <dbReference type="FunCoup" id="A0A1C7NN83">
        <property type="interactions" value="560"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NN83"/>
    <dbReference type="InParanoid" id="A0A1C7NN83"/>
    <dbReference type="OrthoDB" id="10263554at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000329">
        <property type="term" value="C:fungal-type vacuole membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000221">
        <property type="term" value="C:vacuolar proton-transporting V-type ATPase, V1 domain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046961">
        <property type="term" value="F:proton-transporting ATPase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.150">
        <property type="entry name" value="V-type ATPase, subunit H, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004908">
        <property type="entry name" value="ATPase_V1-cplx_hsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011987">
        <property type="entry name" value="ATPase_V1-cplx_hsu_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038497">
        <property type="entry name" value="ATPase_V1-cplx_hsu_C_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10698">
        <property type="entry name" value="V-TYPE PROTON ATPASE SUBUNIT H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10698:SF0">
        <property type="entry name" value="V-TYPE PROTON ATPASE SUBUNIT H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11698">
        <property type="entry name" value="V-ATPase_H_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03224">
        <property type="entry name" value="V-ATPase_H_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF032184">
        <property type="entry name" value="ATPase_V1_H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="4 5" id="KW-0406">Ion transport</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ATPase V1 complex subunit H C-terminal" evidence="6">
        <location>
            <begin position="328"/>
            <end position="444"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRNR" id="PIRNR032184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF11698"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OBZ90591.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="444" mass="50849" checksum="2B959D0C326C1E9B" modified="2016-11-30" version="1">MSEEVPEVPLVYVSNPYLEKKAAAIRQKPILWEGYERASLLTHEQVELIKAIDKKSSTVIHEAMNEKGQAYASLIMYLLQKLSRPDTVQYVCLLTDDIFTASEDHARYFHETSKEDASFPFRPFLKILETDDDFMALQASKLLTVLACSAPSPSHVDLSPFFNWIGSKLTSSNNDIVNLVTQELESLLRVNAYRLAIWNTQNIVKELTHRLLLNKTASTPQIQYQIIFCLWLLTFEPEIAAHINEKYDIIPLLVDIAKSAVKEKVIRVSIATLRNLVEKAPTQNLAAMLVVKLLPFSENLSTRKWSDTDLLEDINFVKERLQENFQSLTTFEQYASEVETGKLEWSPPHKSEVFWKENAQKLEDNNYQLLKSLARLLSTSTNPLVLAIAASDIGYYVKHATKAGRNMLQEIGAKQRIMELMTHEDQEVRYQALLAVQKYMHQAW</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NNA1</accession>
    <name>A0A1C7NNA1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">MPN domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">mpnd</name>
        <name evidence="4" type="ORF">A0J61_01379</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000043">
        <property type="protein sequence ID" value="OBZ90575.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NNA1"/>
    <dbReference type="STRING" id="101091.A0A1C7NNA1"/>
    <dbReference type="InParanoid" id="A0A1C7NNA1"/>
    <dbReference type="OrthoDB" id="118550at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008237">
        <property type="term" value="F:metallopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00167">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.140.10">
        <property type="entry name" value="Cytidine Deaminase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000555">
        <property type="entry name" value="JAMM/MPN+_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050242">
        <property type="entry name" value="JAMM_MPN+_peptidase_M67A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037518">
        <property type="entry name" value="MPN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017930">
        <property type="entry name" value="Myb_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001005">
        <property type="entry name" value="SANT/Myb"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10410">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 3 -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01398">
        <property type="entry name" value="JAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00249">
        <property type="entry name" value="Myb_DNA-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00232">
        <property type="entry name" value="JAB_MPN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00717">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102712">
        <property type="entry name" value="JAB1/MPN domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51294">
        <property type="entry name" value="HTH_MYB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50249">
        <property type="entry name" value="MPN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH myb-type" evidence="3">
        <location>
            <begin position="151"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="domain" description="MPN" evidence="2">
        <location>
            <begin position="357"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="52"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="203"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="268"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="59"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="75"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="100"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="280"/>
            <end position="292"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OBZ90575.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="598" mass="68062" checksum="D3BED6CCB8771575" modified="2016-11-30" version="1">MTNKKSKEQAISKDKEEEMSSALIAQLLAEDAMIQGNEGYYAEYNNDSRAYDPYHVHEEYDDSYEENSEDDFNPRKKYGSKISTGKRGRKKKASVPQKDIVVEKEAEAEKGEEEKVEEESAKAEKKKEKKETVSKKPRKPVPEGHNTGVYTELEEKNFLEGLELFGRDWTKLQQHIATRDANSIRSHAQKHFIKMYRDKIPLPPKVRESGDGYTLSGKPLDPTSSAARPYLSRTDIPSMAKKQKTTNDDPMDVEEATKAVEKQTQNLQIIELKNEKKSSRTPSPSQSTTTTSLANGSETHYDAKGRTSYSSSRLRRQRESVNYGQISSNDDPLTMIKCEPFTGKPGSGSAGCQPFEVTVESNVLLAMDFHAHLMTTEIIGFLAGEWDKESMRMTIREAFPCRSIETGQNDVNVEMDPTSAIETRQLIEERHMKVVGWYHSHPTFIPDPSLIDIENQRNYQTLCRDEHPMSVEPFVGAIVGSYDPALPGSASAINWFHVTNLNSDRPVPKRIVYELKENDCLGKEEEERMFALLDVYKESPEKVVFAEHWRQDVSETKLQKMIKSLGSRIPWIQKALQEEGSVVEDIFLKRVQTSLKDW</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NNG3</accession>
    <name>A0A1C7NNG3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">A0J61_01324</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000040">
        <property type="protein sequence ID" value="OBZ90627.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NNG3"/>
    <dbReference type="InParanoid" id="A0A1C7NNG3"/>
    <dbReference type="OrthoDB" id="5328412at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051685">
        <property type="entry name" value="Ycf3/AcsC/BcsC/TPR_MFPF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44943">
        <property type="entry name" value="CELLULOSE SYNTHASE OPERON PROTEIN C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44943:SF8">
        <property type="entry name" value="TPR REPEAT-CONTAINING PROTEIN MJ0263"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06552">
        <property type="entry name" value="TOM20_plant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0802">TPR repeat</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="176"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OBZ90627.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="508" mass="58053" checksum="2086761EA3A7B01A" modified="2016-11-30" version="1">MGKFTPRKPQKPKAAPKKKKEPETFDEFMEEAIQFEEQGERYHSGDRSQRNYERAVDMYSKAFAVNSNDADCVYNWGRVLFLLVNFLPSHTTPEEKLEKVDESIEKFRKALDLEANKTDAQFNLAQALHQRSEILQETTEIDNSYAASAMALQEAISLFDSVYDLQEKEYLDLNRSNEEEVEEEHQHDEASEHQHEEPTKQHDDKQEFTTVTKVEATTPYSLIETLLSTAETMTTMASMLASFPASMNLFSKAKAKLGLAEKWLAKIPSTDENEKERIAARIQINLKESAAYAAMADRSFVASNTVDSSLFEKAIERLDEIIETHDTRNVEAMCDRGDVLTSFGQAIEEVANKKNLPLVPEKDGKEVWQLYATATKSFQSALTLEPKNLRILNKMGDLSLIRARLSLPVAERNRIQLLKNAAFYFKHAVEVDKEVLTSGYLGWAMSEWAMEEWADVANKKEDALKIVRVWIKRGGNGSLFRSLAEDNETWDEDFVEFIIEAFFDEESE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NNW1</accession>
    <name>A0A1C7NNW1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Subtilisin-like protease 8</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">SUB8_1</name>
        <name evidence="8" type="ORF">A0J61_01385</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5 6">Belongs to the peptidase S8 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000043">
        <property type="protein sequence ID" value="OBZ90569.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NNW1"/>
    <dbReference type="STRING" id="101091.A0A1C7NNW1"/>
    <dbReference type="InParanoid" id="A0A1C7NNW1"/>
    <dbReference type="OrthoDB" id="206201at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04077">
        <property type="entry name" value="Peptidases_S8_PCSK9_ProteinaseK_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.200:FF:000014">
        <property type="entry name" value="Proteinase K"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.200">
        <property type="entry name" value="Peptidase S8/S53 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034193">
        <property type="entry name" value="PCSK9_ProteinaseK-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000209">
        <property type="entry name" value="Peptidase_S8/S53_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036852">
        <property type="entry name" value="Peptidase_S8/S53_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023827">
        <property type="entry name" value="Peptidase_S8_Asp-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023828">
        <property type="entry name" value="Peptidase_S8_Ser-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050131">
        <property type="entry name" value="Peptidase_S8_subtilisin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015500">
        <property type="entry name" value="Peptidase_S8_subtilisin-rel"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43806:SF11">
        <property type="entry name" value="CEREVISIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43806">
        <property type="entry name" value="PEPTIDASE S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00082">
        <property type="entry name" value="Peptidase_S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00723">
        <property type="entry name" value="SUBTILISIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52743">
        <property type="entry name" value="Subtilisin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51892">
        <property type="entry name" value="SUBTILASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00136">
        <property type="entry name" value="SUBTILASE_ASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00138">
        <property type="entry name" value="SUBTILASE_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 5 6" id="KW-0645">Protease</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5 6" id="KW-0720">Serine protease</keyword>
    <feature type="domain" description="Peptidase S8/S53" evidence="7">
        <location>
            <begin position="141"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="5">
        <location>
            <position position="150"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="5">
        <location>
            <position position="182"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="5">
        <location>
            <position position="336"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003355"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OBZ90569.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="394" mass="43080" checksum="CEFFC9AEB78B6CB3" modified="2016-11-30" version="1">MMLSHRWTYLSSITNNQTSLQKNSDFSAASVHNDLKINHIDIGPEFVAITGVFSDNDFVNYLNGQSEIDYIEENHKYSVRTIQSYQEQQKAGTDEIHVPSNSQDIRKRQLRVESSPNWGLARISQRQMTNMNEYTYDEMGGSGVTVFVLDSGVFVDHSDFEGRASHSINTILYEDENDLGGHGTHVASKIIGKKYGVAKGAKVRSVKILNRDGDGSTSSLLKGVEHVAQNAIPGKSLINLSLSGKRSKLVDDALNNLVLRYNIPVFVSAGNDGADACLFSPSSNPNVFSVGAADEHDAVPKFSNIGACVEMYAPGRNIESAYIGNQYSFRAMDGTSMASPHVAGIAANLMGRHNFSSAQEVYDTLMSIATADILHFDTSRTSSPNYNLLAYSQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NNY4</accession>
    <name>A0A1C7NNY4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 12">T-complex protein 1 subunit gamma</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">cct3</name>
        <name evidence="14" type="ORF">A0J61_01107</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. Known to play a role, in vitro, in the folding of actin and tubulin.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Component of the T-complex protein 1 (TCP1) complex.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Heterooligomeric complex of about 850 to 900 kDa that forms two stacked rings, 12 to 16 nm in diameter.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the TCP-1 chaperonin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000032">
        <property type="protein sequence ID" value="OBZ90832.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NNY4"/>
    <dbReference type="FunCoup" id="A0A1C7NNY4">
        <property type="interactions" value="818"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NNY4"/>
    <dbReference type="InParanoid" id="A0A1C7NNY4"/>
    <dbReference type="OrthoDB" id="10248520at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005832">
        <property type="term" value="C:chaperonin-containing T-complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd03337">
        <property type="entry name" value="TCP1_gamma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.560.10:FF:000073">
        <property type="entry name" value="T-complex protein 1 subunit gamma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.560.10:FF:000085">
        <property type="entry name" value="T-complex protein 1 subunit gamma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.50.7.10:FF:000005">
        <property type="entry name" value="T-complex protein 1 subunit gamma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.7.10">
        <property type="entry name" value="GroEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.560.10">
        <property type="entry name" value="GroEL-like equatorial domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.260.10">
        <property type="entry name" value="TCP-1-like chaperonin intermediate domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012719">
        <property type="entry name" value="Chap_CCT_gamma"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017998">
        <property type="entry name" value="Chaperone_TCP-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002194">
        <property type="entry name" value="Chaperonin_TCP-1_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002423">
        <property type="entry name" value="Cpn60/GroEL/TCP-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027409">
        <property type="entry name" value="GroEL-like_apical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027413">
        <property type="entry name" value="GROEL-like_equatorial_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027410">
        <property type="entry name" value="TCP-1-like_intermed_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053374">
        <property type="entry name" value="TCP-1_chaperonin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054827">
        <property type="entry name" value="thermosome_alpha"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02344">
        <property type="entry name" value="chap_CCT_gamma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF041082">
        <property type="entry name" value="thermosome_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF041083">
        <property type="entry name" value="thermosome_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11353">
        <property type="entry name" value="CHAPERONIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00118">
        <property type="entry name" value="Cpn60_TCP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00304">
        <property type="entry name" value="TCOMPLEXTCP1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52029">
        <property type="entry name" value="GroEL apical domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48592">
        <property type="entry name" value="GroEL equatorial domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54849">
        <property type="entry name" value="GroEL-intermediate domain like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00750">
        <property type="entry name" value="TCP1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00751">
        <property type="entry name" value="TCP1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00995">
        <property type="entry name" value="TCP1_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9 11" id="KW-0143">Chaperone</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="527"/>
            <end position="548"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="534"/>
            <end position="548"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011381"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00017187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00024677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU004187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU004191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="OBZ90832.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="548" mass="60373" checksum="C8C452AF1FE4AE69" modified="2016-11-30" version="1">MQAPVLVMNTNMERESGRKAQLSNITAAKTVADVIRTCLGPRSMLKMLLDPMGGILLTNDGNAILREIEVDHPAAKSMIELSRTQDEEVGDGTTSVIILAGEVLAGALPHVQNNIHPIVIISAFKKALEDALQIVEEISTPVDVQNTEEMLTLIKSSIGTKFTSNWSELMCKLALDAVRCVAIEEESTGKTEVDIKRYARVEKIPGGEIEQSQVLDGIILNKDVTHPKMRRRIENPRVILLDCPLEYKKGESQTNIEISKEADWNRILQIEEEQVKAMCDKIISLKPDLVFTEKGVSDLAQHYFVKANITAIRRVRKTDNNRIARAVGATIVNRVDDLRESDVGTKCGLFNIDKIGDEYFTFLTQCQDPKACSIILRGPSKDIINEVERNLQDAMCVARNVFYSAKLAPGGGATEMAVAVKLEEKAKLIEGVEQWPYRSVAEAMEVIPRTLIQNCGGNAIKTLTQLRAKHATGEHSFGIDGEAGKVVDMKDYGVWEPTAVKIQTIKTAIESACLLLRVDDIVSGLSKNKGPAPQGGAEQQEMMEQPQM</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NPP5</accession>
    <name>A0A1C7NPP5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">SDO1-like protein C21C3.19</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_00842</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000022">
        <property type="protein sequence ID" value="OBZ91087.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NPP5"/>
    <dbReference type="FunCoup" id="A0A1C7NPP5">
        <property type="interactions" value="36"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NPP5"/>
    <dbReference type="InParanoid" id="A0A1C7NPP5"/>
    <dbReference type="OrthoDB" id="2567806at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1250.10">
        <property type="entry name" value="Ribosome maturation protein SBDS, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036786">
        <property type="entry name" value="Ribosome_mat_SBDS_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019783">
        <property type="entry name" value="SDO1/SBDS_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01172">
        <property type="entry name" value="SBDS_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89895">
        <property type="entry name" value="FYSH domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ribosome maturation protein SDO1/SBDS N-terminal" evidence="1">
        <location>
            <begin position="6"/>
            <end position="90"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ91087.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="93" mass="10208" checksum="9B0EE554C7FC091D" modified="2016-11-30" version="1">MPSEHAVKVVYKGTENTEFFVIANSEQVSKWKSDKSTPLVDVVQSFDVYTTSAGGSTGEYIKPPKGVLESNFNTSNTDEIVKKIISEGEEKGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NPX7</accession>
    <name>A0A1C7NPX7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Mannosyltransferase</fullName>
            <ecNumber evidence="11">2.4.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">PIGZ</name>
        <name evidence="13" type="ORF">A0J61_01453</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="2">Glycolipid biosynthesis; glycosylphosphatidylinositol-anchor biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 11">Endoplasmic reticulum membrane</location>
            <topology evidence="1 11">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the glycosyltransferase 22 family. PIGZ subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.-" evidence="11"/>
    <dbReference type="EMBL" id="LUGH01000046">
        <property type="protein sequence ID" value="OBZ90496.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NPX7"/>
    <dbReference type="FunCoup" id="A0A1C7NPX7">
        <property type="interactions" value="100"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NPX7"/>
    <dbReference type="InParanoid" id="A0A1C7NPX7"/>
    <dbReference type="OrthoDB" id="10066429at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000026">
        <property type="term" value="F:alpha-1,2-mannosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006506">
        <property type="term" value="P:GPI anchor biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005599">
        <property type="entry name" value="GPI_mannosylTrfase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22760">
        <property type="entry name" value="GLYCOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22760:SF3">
        <property type="entry name" value="GPI MANNOSYLTRANSFERASE 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03901">
        <property type="entry name" value="Glyco_transf_22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 11" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="4 11 13" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="3" id="KW-0337">GPI-anchor biosynthesis</keyword>
    <keyword evidence="9 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="12" id="KW-0732">Signal</keyword>
    <keyword evidence="5 13" id="KW-0808">Transferase</keyword>
    <keyword evidence="6 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="12">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008889823" description="Mannosyltransferase" evidence="12">
        <location>
            <begin position="21"/>
            <end position="592"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="121"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="170"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="212"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="304"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="336"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="386"/>
            <end position="406"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00038466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU363075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="OBZ90496.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="592" mass="66743" checksum="0F20F8ACC7882B9C" modified="2016-11-30" version="1">MKGVIVTFVCLGLLLRWFTAILPGYIHPDEFFQNPEITSGMIFKIETLIPWEYQPEHASRSIVSPLLTTGLPFFILKQFLPNDQLPSGTTLFYTERLSSLLWSLLVDMSVYKLCRHMGTDPLVPMVLVATSLVTFVFGTRPFSNSFESILLCQSLVVYADYLKEASYKRAYFLGCLFALGVFTRITFPLYALPIGIVFLYQTYKNNKNVGAWIVSIVPMFLGLFTTSAVCIALDSLYYGTLWLTVNDQPMKDVLNALSILANPALLATVQVHGHVVLTPFNNLSYNLDVSNLAQHGLHARYTHVLVNLPLLYGPLAIFCLMYIPKAYQKIRQGATQGAHLFCVLLAIFASGLIGLSIMPHQEARFLCPLLVPLVLMYNWDQPVLPIPFFIAWLLFNLITTCIFGLVHQGGVVPALNFVQRFSSGIQECHLAGADELACTLLPNHESIPTDFELTTHVVFYKTYMPPRHLLTIPLDNTTHQIRVTDLSSDFDALVEVLERRPGVPLRRHSKNKVEIDFVRSREGFERTLLVTPGFVDLPKIENHRYLLVHKLGPHVSFDDFDKLTEVMSESDSPEGQMSLDVYLMLSEKDNLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NQ17</accession>
    <name>A0A1C7NQ17_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">40S ribosomal protein S25</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">RPS25_1</name>
        <name evidence="6" type="synonym">RPS25_2</name>
        <name evidence="7" type="ORF">A0J61_00762</name>
        <name evidence="6" type="ORF">A0J61_02279</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the eukaryotic ribosomal protein eS25 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000083">
        <property type="protein sequence ID" value="OBZ89680.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="LUGH01000019">
        <property type="protein sequence ID" value="OBZ91193.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NQ17"/>
    <dbReference type="FunCoup" id="A0A1C7NQ17">
        <property type="interactions" value="520"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NQ17"/>
    <dbReference type="InParanoid" id="A0A1C7NQ17"/>
    <dbReference type="OrthoDB" id="10263513at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.63.20:FF:000001">
        <property type="entry name" value="40S ribosomal protein S25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.63.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004977">
        <property type="entry name" value="Ribosomal_eS25"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12850">
        <property type="entry name" value="40S RIBOSOMAL PROTEIN S25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03297">
        <property type="entry name" value="Ribosomal_S25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 7" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="17"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU366057"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OBZ89680.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OBZ91193.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="113" mass="12544" checksum="CAADF2839AFA83F2" modified="2016-11-30" version="1">MAKKDVAAKPSSSSGGKKAKKKWSAKKVKDKANNLVILDKPTYERLFKEVPTYKLISQSVLVDRLKLNGSLARIAIRELEAQGLIKPISRHHAQIIYTRATGDEKKAAADDEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NQE9</accession>
    <name>A0A1C7NQE9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Transcription factor Dp-1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">Tfdp1_0</name>
        <name evidence="9" type="ORF">A0J61_00769</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the E2F/DP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000019">
        <property type="protein sequence ID" value="OBZ91190.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NQE9"/>
    <dbReference type="STRING" id="101091.A0A1C7NQE9"/>
    <dbReference type="InParanoid" id="A0A1C7NQE9"/>
    <dbReference type="OrthoDB" id="552115at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005667">
        <property type="term" value="C:transcription regulator complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000977">
        <property type="term" value="F:RNA polymerase II transcription regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051726">
        <property type="term" value="P:regulation of cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.10:FF:000360">
        <property type="entry name" value="Transcription factor Dp-1, a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.140.80">
        <property type="entry name" value="Transcription factor DP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037241">
        <property type="entry name" value="E2F-DP_heterodim"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003316">
        <property type="entry name" value="E2F_WHTH_DNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038168">
        <property type="entry name" value="TF_DP_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014889">
        <property type="entry name" value="Transc_factor_DP_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015648">
        <property type="entry name" value="Transcrpt_fac_DP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12548">
        <property type="entry name" value="TRANSCRIPTION FACTOR DP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12548:SF9">
        <property type="entry name" value="TRANSCRIPTION FACTOR DP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08781">
        <property type="entry name" value="DP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02319">
        <property type="entry name" value="WHD_E2F_TDP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01372">
        <property type="entry name" value="E2F_TDP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144074">
        <property type="entry name" value="E2F-DP heterodimerization region"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6 7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7" id="KW-0804">Transcription</keyword>
    <keyword evidence="3 7" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="E2F/DP family winged-helix DNA-binding" evidence="8">
        <location>
            <begin position="98"/>
            <end position="172"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010940"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003796"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM01372"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OBZ91190.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="285" mass="32463" checksum="FCFB4CF6A3F9C97C" modified="2016-11-30" version="1">MLPDRCQDNHSLLLPPILSSNIPLSPPFSSCSSLSSSSLPPSPNSVAEVNFSSLPKKGSIQSLLNSAQCPMVNKKRKRQLKPQQSQQRFHQPYHKDARPTKGLRLFSKQVCDKVAEKGITTYNQVADELAAEIHQHSNVDQKNIRRRVYDALNVLMALDIIAKDRKQIKWLGMPTNDLEKEIEREESRHKELLETVQRSRHVLNDTLVNFTRLEKLVQRNRQEQQANAPQTVVRLPFFMMSSSQDIYTDSNEKEAFVSLGASYAIHQDTDILAKLWPSHQITTVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NRA3</accession>
    <name>A0A1C7NRA3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Metal tolerance protein 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">MTP3</name>
        <name evidence="10" type="ORF">A0J61_00356</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000007">
        <property type="protein sequence ID" value="OBZ91622.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NRA3"/>
    <dbReference type="STRING" id="101091.A0A1C7NRA3"/>
    <dbReference type="InParanoid" id="A0A1C7NRA3"/>
    <dbReference type="OrthoDB" id="78296at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008324">
        <property type="term" value="F:monoatomic cation transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098771">
        <property type="term" value="P:inorganic ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030003">
        <property type="term" value="P:intracellular monoatomic cation homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1510.10:FF:000005">
        <property type="entry name" value="Putative Cation diffusion facilitator 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1510.10">
        <property type="entry name" value="Cation efflux protein transmembrane domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1350">
        <property type="entry name" value="Cation efflux protein, cytoplasmic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002524">
        <property type="entry name" value="Cation_efflux"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027470">
        <property type="entry name" value="Cation_efflux_CTD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036837">
        <property type="entry name" value="Cation_efflux_CTD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058533">
        <property type="entry name" value="Cation_efflux_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027469">
        <property type="entry name" value="Cation_efflux_TMD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050291">
        <property type="entry name" value="CDF_Transporter"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01297">
        <property type="entry name" value="CDF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43840:SF4">
        <property type="entry name" value="CDF DIVALENT METAL CATION TRANSPORTER (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43840">
        <property type="entry name" value="MITOCHONDRIAL METAL TRANSPORTER 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01545">
        <property type="entry name" value="Cation_efflux"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16916">
        <property type="entry name" value="ZT_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160240">
        <property type="entry name" value="Cation efflux protein cytoplasmic domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161111">
        <property type="entry name" value="Cation efflux protein transmembrane domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="145"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="173"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="215"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="253"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="292"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="316"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="domain" description="Cation efflux protein transmembrane" evidence="8">
        <location>
            <begin position="149"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="domain" description="Cation efflux protein cytoplasmic" evidence="9">
        <location>
            <begin position="348"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="96"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="121"/>
            <end position="134"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01545"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF16916"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OBZ91622.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="441" mass="49611" checksum="02BDCF675B377FDD" modified="2016-11-30" version="1">MVSEQEDTRNSSKRFQHRTSLTTAVSETLPPPVHFESLRVSDDQLKTYQNKKVREFYQDQNEMIDRYAQVDRVIDSIKRGETFLSKAAYGSIPGDIENGFGQDENGDTMPLDVGAGDRQPLLSSSRSSTPDNTNNKKSPMWVIHLAINLSFFANVALFITKIVLSWFSGSMALLASAFESFLDIVSNAIIFFTVRIIRQKNYYTYPVGKSRMEPLGIVVFAVIITTSFSQVLISSVEKLTSGTAPDEIDLSMQALIVLGINVAIKAALWIWCRSIKGSSSVEALAYDHENDVVFTISSTLFPVVGNYMSWNWLDPLGAILLSIYIIYEWMSVLVENIRRLTGQAASTDDIKQLTYMAYRFSKKIQAVDTVRAYYIGDRLLVEVDIILPPDCPLKEAHDVGEALQDALELMDNVERAFVHLDYSAEHEIEHRRVVDDVGFNP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NRE6</accession>
    <name>A0A1C7NRE6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">V-type proton ATPase subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">VhaAC39-1</name>
        <name evidence="8" type="ORF">A0J61_00255</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5 7">Subunit of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments. This subunit is a non-integral membrane component of the membrane pore domain and is required for proper assembly of the V0 sector. Might be involved in the regulated assembly of V1 subunits onto the membrane sector or alternatively may prevent the passage of protons through V0 pores.</text>
    </comment>
    <comment type="function">
        <text evidence="6">Subunit of the integral membrane V0 complex of vacuolar ATPase. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the V-ATPase V0D/AC39 subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000005">
        <property type="protein sequence ID" value="OBZ91705.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NRE6"/>
    <dbReference type="FunCoup" id="A0A1C7NRE6">
        <property type="interactions" value="328"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NRE6"/>
    <dbReference type="InParanoid" id="A0A1C7NRE6"/>
    <dbReference type="OrthoDB" id="10250083at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000329">
        <property type="term" value="C:fungal-type vacuole membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000220">
        <property type="term" value="C:vacuolar proton-transporting V-type ATPase, V0 domain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046961">
        <property type="term" value="F:proton-transporting ATPase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007034">
        <property type="term" value="P:vacuolar transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.132.50:FF:000002">
        <property type="entry name" value="V-type proton ATPase subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1690.10:FF:000001">
        <property type="entry name" value="V-type proton ATPase subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1690.10:FF:000003">
        <property type="entry name" value="V-type proton ATPase subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.132.50">
        <property type="entry name" value="ATP synthase (C/AC39) subunit, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1690.10">
        <property type="entry name" value="V-type ATP synthase subunit C domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036079">
        <property type="entry name" value="ATPase_csu/dsu_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002843">
        <property type="entry name" value="ATPase_V0-cplx_csu/dsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016727">
        <property type="entry name" value="ATPase_V0-cplx_dsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035067">
        <property type="entry name" value="V-type_ATPase_csu/dsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044911">
        <property type="entry name" value="V-type_ATPase_csu/dsu_dom_3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11028">
        <property type="entry name" value="VACUOLAR ATP SYNTHASE SUBUNIT AC39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01992">
        <property type="entry name" value="vATP-synt_AC39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF018497">
        <property type="entry name" value="V-ATP_synth_D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103486">
        <property type="entry name" value="V-type ATP synthase subunit C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="4 7" id="KW-0406">Ion transport</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006709"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00059115"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00059209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRNR" id="PIRNR018497"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OBZ91705.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="346" mass="39752" checksum="B5356D9E47DE896D" modified="2016-11-30" version="1">MTSALTYNEKEGFVDGILRGYYSGILNSTQYLNFTQCETLEDLRLQLGATDYGTLLQNEPSPIATSTIAEKLTQNLVEEFEYIRSNAVQPLAKFLDYITYQYMIDNVILIITGTLHERDTHELLERCHPLGVFDTMPALCVATTVSELYNTVLVETPLAPYFSNCLSAHDLDELNIEIIRNTLYKAYLEDFYQFCQSIGGPTAEVMGEILQFEADRRTINITINSFGTELPKEDRKKLYPTIGRLYPEGNARLAVADEVDQVKAVCEVIHEYRSFFDTNTNNKTLEDKFFETEVALNKQAFMQQFHYGVFFAYVKLKEQEIRNIVWIAECISQNQKDRINSYIPIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NRQ6</accession>
    <name>A0A1C7NRQ6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">Amine oxidase</fullName>
            <ecNumber evidence="15">1.4.3.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="20" type="primary">cao1</name>
        <name evidence="20" type="ORF">A0J61_00219</name>
    </gene>
    <organism evidence="20 21">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="20 21" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="20 21">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>a primary methyl amine + O2 + H2O = an aldehyde + H2O2 + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:16153"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16240"/>
            <dbReference type="ChEBI" id="CHEBI:17478"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:228804"/>
            <dbReference type="EC" id="1.4.3.21"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Cu cation</name>
            <dbReference type="ChEBI" id="CHEBI:23378"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="15">
            <name>L-topaquinone</name>
            <dbReference type="ChEBI" id="CHEBI:79027"/>
        </cofactor>
        <cofactor evidence="15">
            <name>Cu cation</name>
            <dbReference type="ChEBI" id="CHEBI:23378"/>
        </cofactor>
        <text evidence="15">Contains 1 topaquinone per subunit.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="14">
            <name>L-topaquinone</name>
            <dbReference type="ChEBI" id="CHEBI:79027"/>
        </cofactor>
        <text evidence="14">Contains 1 topaquinone per subunit.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="5">Homodimer.</text>
    </comment>
    <comment type="PTM">
        <text evidence="14 15">Topaquinone (TPQ) is generated by copper-dependent autoxidation of a specific tyrosyl residue.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 15">Belongs to the copper/topaquinone oxidase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="20">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.4.3.-" evidence="15"/>
    <dbReference type="EMBL" id="LUGH01000004">
        <property type="protein sequence ID" value="OBZ91773.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NRQ6"/>
    <dbReference type="FunCoup" id="A0A1C7NRQ6">
        <property type="interactions" value="57"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NRQ6"/>
    <dbReference type="InParanoid" id="A0A1C7NRQ6"/>
    <dbReference type="OrthoDB" id="5379943at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005507">
        <property type="term" value="F:copper ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008131">
        <property type="term" value="F:primary methylamine oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048038">
        <property type="term" value="F:quinone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009308">
        <property type="term" value="P:amine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="2.70.98.20:FF:000001">
        <property type="entry name" value="Amine oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.450.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.98.20">
        <property type="entry name" value="Copper amine oxidase, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049947">
        <property type="entry name" value="Cu_Am_Ox_Cu-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049948">
        <property type="entry name" value="Cu_Am_ox_TPQ-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000269">
        <property type="entry name" value="Cu_amine_oxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015798">
        <property type="entry name" value="Cu_amine_oxidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036460">
        <property type="entry name" value="Cu_amine_oxidase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016182">
        <property type="entry name" value="Cu_amine_oxidase_N-reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015800">
        <property type="entry name" value="Cu_amine_oxidase_N2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015802">
        <property type="entry name" value="Cu_amine_oxidase_N3"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF008559">
        <property type="entry name" value="PRK11504.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10638">
        <property type="entry name" value="COPPER AMINE OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10638:SF86">
        <property type="entry name" value="COPPER AMINE OXIDASE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01179">
        <property type="entry name" value="Cu_amine_oxid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02727">
        <property type="entry name" value="Cu_amine_oxidN2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02728">
        <property type="entry name" value="Cu_amine_oxidN3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49998">
        <property type="entry name" value="Amine oxidase catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54416">
        <property type="entry name" value="Amine oxidase N-terminal region"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01164">
        <property type="entry name" value="COPPER_AMINE_OXID_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01165">
        <property type="entry name" value="COPPER_AMINE_OXID_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 15" id="KW-0186">Copper</keyword>
    <keyword evidence="10" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="11" id="KW-0464">Manganese</keyword>
    <keyword evidence="6 15" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8 15" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 13 15" id="KW-0801">TPQ</keyword>
    <feature type="domain" description="Copper amine oxidase N2-terminal" evidence="18">
        <location>
            <begin position="20"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="domain" description="Copper amine oxidase N3-terminal" evidence="19">
        <location>
            <begin position="116"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="domain" description="Copper amine oxidase catalytic" evidence="17">
        <location>
            <begin position="248"/>
            <end position="655"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="660"/>
            <end position="684"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="13">
        <location>
            <position position="323"/>
        </location>
    </feature>
    <feature type="active site" description="Schiff-base intermediate with substrate; via topaquinone" evidence="13">
        <location>
            <position position="407"/>
        </location>
    </feature>
    <feature type="modified residue" description="2',4',5'-topaquinone" evidence="14">
        <location>
            <position position="407"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001935"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007983"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022772"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00048032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR600269-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PIRSR" id="PIRSR600269-51"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="RuleBase" id="RU000672"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF01179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="Pfam" id="PF02727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="Pfam" id="PF02728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="OBZ91773.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="684" mass="78727" checksum="E64A58A1655A5C1A" modified="2016-11-30" version="1">MSTVKESKTANSVNLTHHTHPLDQLSANEIARVATITRQAKPDIDFVFNTITLWEPKKSLMLSYLGWDTSKPRITQIEREAFVVTLEKLTMKCYEGIVSLTTGKLTSWKYIPDVQPMLTMDDMFEVEELVLKSELVRQECLELGIKDMSTVFSDPWAIARHISHPGREKRLMQALMYYRACEEDNQYAHPLDFIPIIDLGQMKVVSIERIKPRSSKFARPTIPLQQHNFLPELINENDYRKDIKPLIVQQPQGVSFTVKGNEIDWQKWNMRISMNYREGLVIHNVSYQDGREKRPLFYRISLSEMVVPYAETNDPHHRKHAFDVGEYGMGLCTNSLALGCDCLGSIYYFDAVFNDHTGKPIEIPNAICLHEEDYGVLMKHTDYRNGRAHTIRSRRLVISQFVTVANYDYGLYYYFYQDGTFEYEVKATGILNTHVLAEDESPSGMGTIVAPQINAQYHQHFFTMRIDPMIDGISNSVQRVDTYSLPYPTGHPLNPFGNGFTTKYTTLKNTKEGQQIDNWETSRYFKIVNQDRIHPYSQTPVGWKITSGHTAPFYAQPDSLVAERAGFAKKTLWVTPYDEHQMFAGGFYCNQSAGDDTVEVWANRELRNIEQTDIVLWYTFGITHLPRVEDFPIMPVEYCGFIMKPFNFFMANPALDVPPPNKKSNQSMNVKDKVKPTNCCSTKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NS01</accession>
    <name>A0A1C7NS01_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="11">tRNA-dihydrouridine(20) synthase [NAD(P)+]-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">DUS2</name>
        <name evidence="11" type="ORF">A0J61_01924</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>a 5,6-dihydrouridine in mRNA + NAD(+) = a uridine in mRNA + NADH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:69851"/>
            <dbReference type="Rhea" id="RHEA-COMP:14658"/>
            <dbReference type="Rhea" id="RHEA-COMP:17789"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="ChEBI" id="CHEBI:74443"/>
        </reaction>
        <physiologicalReaction direction="right-to-left" evidence="7">
            <dbReference type="Rhea" id="RHEA:69853"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>a 5,6-dihydrouridine in mRNA + NADP(+) = a uridine in mRNA + NADPH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:69855"/>
            <dbReference type="Rhea" id="RHEA-COMP:14658"/>
            <dbReference type="Rhea" id="RHEA-COMP:17789"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="ChEBI" id="CHEBI:74443"/>
        </reaction>
        <physiologicalReaction direction="right-to-left" evidence="8">
            <dbReference type="Rhea" id="RHEA:69857"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000067">
        <property type="protein sequence ID" value="OBZ90024.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NS01"/>
    <dbReference type="FunCoup" id="A0A1C7NS01">
        <property type="interactions" value="563"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NS01"/>
    <dbReference type="InParanoid" id="A0A1C7NS01"/>
    <dbReference type="OrthoDB" id="10262250at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102264">
        <property type="term" value="F:tRNA-dihydrouridine20 synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02801">
        <property type="entry name" value="DUS_like_FMN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035587">
        <property type="entry name" value="DUS-like_FMN-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052582">
        <property type="entry name" value="tRNA-DUS-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018517">
        <property type="entry name" value="tRNA_hU_synthase_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45936">
        <property type="entry name" value="TRNA-DIHYDROURIDINE(20) SYNTHASE [NAD(P)+]-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45936:SF1">
        <property type="entry name" value="TRNA-DIHYDROURIDINE(20) SYNTHASE [NAD(P)+]-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01207">
        <property type="entry name" value="Dus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51395">
        <property type="entry name" value="FMN-linked oxidoreductases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01136">
        <property type="entry name" value="UPF0034"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="3" id="KW-0288">FMN</keyword>
    <keyword evidence="4" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="DUS-like FMN-binding" evidence="10">
        <location>
            <begin position="15"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="335"/>
            <end position="370"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00048342"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00049447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF01207"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="OBZ90024.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="370" mass="41052" checksum="4C6C5FCDF4980FE2" modified="2016-11-30" version="1">MSATHPDIDYANKAILAPMVRIGTLPMRLVALDYGADLVWSEELVDKRIIGSVRQINHATGTIDYYKGKSLTFSTCDAEKGKVILQLGTADADLALQAALTLKQDVAAIDVNCGCPKKFSIQGGMGAALLSNPDNLQKILTKLVQHSGMPVTCKIRLLETKEKTLDLVRMIVSTGVKALTVHCRTKEQRSTEKANWDALKDIVQLVKSVSDIPVVVNGDVFQYSDIEKAKSLTGADSVMIARGAQWNPSAFRKEGLLPFDTVVQAYIKKAVDLDNLFQNTKYVLLSMNTEDTKHTRSDLYTKIQRSKSMHTICELFDLVDYYENAVAQQKARLEEAEKIQSAENGKRERGAEDEASQKDQEHVEKKTKTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NS75</accession>
    <name>A0A1C7NS75_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">60S ribosomal protein L9-A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">rpl9a_1</name>
        <name evidence="5" type="ORF">A0J61_00708</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uL6 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000017">
        <property type="protein sequence ID" value="OBZ91256.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NS75"/>
    <dbReference type="FunCoup" id="A0A1C7NS75">
        <property type="interactions" value="444"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NS75"/>
    <dbReference type="InParanoid" id="A0A1C7NS75"/>
    <dbReference type="OrthoDB" id="10252633at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022625">
        <property type="term" value="C:cytosolic large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002181">
        <property type="term" value="P:cytoplasmic translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.930.12:FF:000003">
        <property type="entry name" value="60S ribosomal protein L9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.930.12:FF:000004">
        <property type="entry name" value="60S ribosomal protein L9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.930.12">
        <property type="entry name" value="Ribosomal protein L6, alpha-beta domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000702">
        <property type="entry name" value="Ribosomal_uL6-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036789">
        <property type="entry name" value="Ribosomal_uL6-like_a/b-dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020040">
        <property type="entry name" value="Ribosomal_uL6_a/b-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002359">
        <property type="entry name" value="Ribosomal_uL6_CS2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11655:SF16">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11655">
        <property type="entry name" value="60S/50S RIBOSOMAL PROTEIN L6/L9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00347">
        <property type="entry name" value="Ribosomal_L6"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002162">
        <property type="entry name" value="Ribosomal_L6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56053">
        <property type="entry name" value="Ribosomal protein L6"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00700">
        <property type="entry name" value="RIBOSOMAL_L6_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 5" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Large ribosomal subunit protein uL6 alpha-beta" evidence="4">
        <location>
            <begin position="12"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="domain" description="Large ribosomal subunit protein uL6 alpha-beta" evidence="4">
        <location>
            <begin position="97"/>
            <end position="175"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009356"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OBZ91256.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="186" mass="20863" checksum="7D400E43330AB50A" modified="2016-11-30" version="1">MKDIYKSDELAIPEGVKVSIKSRNVTVEGPRGTLTKNLRHLNIEITVKGDKINFVVHHGLRKHVACIRTVRSLINNMITGVTKGFEYKMRYVYAHFPINVIINDAGDAVEIRNFLGQKVVFHVKMREGVTVVSSKAQKDELILTGNSLEAVSQSAADIQQSCLVKNKDIRKFLDGIYVSERNVLEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NV41</accession>
    <name>A0A1C7NV41_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Serine/threonine-protein kinase srk1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">srk1_3</name>
        <name evidence="6" type="ORF">A0J61_00607</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000014">
        <property type="protein sequence ID" value="OBZ91344.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NV41"/>
    <dbReference type="FunCoup" id="A0A1C7NV41">
        <property type="interactions" value="416"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NV41"/>
    <dbReference type="InParanoid" id="A0A1C7NV41"/>
    <dbReference type="OrthoDB" id="1738954at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004672">
        <property type="term" value="F:protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000425">
        <property type="entry name" value="Putative calcium/calmodulin-dependent protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24347">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0418">Kinase</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="5">
        <location>
            <begin position="54"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="364"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="441"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="376"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="470"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="87"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OBZ91344.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="560" mass="64208" checksum="D51F1DAD24ABC09A" modified="2016-11-30" version="1">MLAQIKSLFKQKKTYSKDLTPEEKRHNKDVATRLVQEEKQRKNVLPKYPGLERFEMIEKIGEGAFSYVYKARDTLTDKEVAVKVVRKKELDASESNKNHLHPNMKKKTKATERANILKEVQIMRNMNHKNIVQLIQFSESDDYYFLVLELCQGGELFHRIVKLTYFSEDLARHVITQVAEGIRYLHEECGVVHRDIKPENILFEPIPIIKRDKVENPFNDEDKEDEGVFTEGVGGGGIGVVKLADFGLSKVIWDNSTLTPCGTVGYTAPEIVRDQKYSKSVDMWAIGCVLYTILCGFPPFYDESIRALTHKVARGEYTFLSPWWDPISPAAKDLIRNLLTVDPEKRYTIEEFFQHPWVTRSTFPAVPKKKTNDPRAQAMQNAAQQAQDRLQKKKEEVMPTNEQEDNKKNKATGKRTDLFSPGINSIKEILDITYAVQRMGEEKKKKGQPGHTPGQELNMPNFAPGGYDSISEEEEEDEEEVKEVKKPHHGIDREVIAMAEQMVHDGKGIAPAAFNMTLEQKQKTQQSDVITPTSRRRRNMFELDLTKATLLKNRRMAPVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NV82</accession>
    <name>A0A1C7NV82_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_00581</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000013">
        <property type="protein sequence ID" value="OBZ91384.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NV82"/>
    <dbReference type="InParanoid" id="A0A1C7NV82"/>
    <dbReference type="OrthoDB" id="2124108at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ91384.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="302" mass="35659" checksum="8742D6277308FD8B" modified="2016-11-30" version="1">MSQQETDTLLLGGFDFDDDDFVTKEKTKINIAQVDYSAKLETDGWFHDHEKTVDELMLEQHGPNQIRNAIEHDYFYKRYDKALTLALGFIRVAQTNKQCKVSGTKEMTDIAMHCAAKLNRLDVLEDLLDNKTHVQDTGLFLVRGKFYPMIGKYSEAMEAYVQYQRERKLDYRVWSGMAQVFMLSATRRPAENEMRYHLANLSMQRAIHIFTNSRWNKRIDFVQARFQRDLATLETRLKETQQYGGQADKFIEWMNSRETEDKQQAGGLEEFHWDDIMWIYKDWVLRQDLDLADHDIKAVKDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MTQ8</accession>
    <name>A0A1C7MTQ8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_11743</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01002418">
        <property type="protein sequence ID" value="OBZ80208.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MTQ8"/>
    <dbReference type="STRING" id="101091.A0A1C7MTQ8"/>
    <dbReference type="InParanoid" id="A0A1C7MTQ8"/>
    <dbReference type="OrthoDB" id="10004862at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ80208.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="145" mass="16394" checksum="9B868E650B3A57E8" modified="2016-11-30" version="1" fragment="single">VFSATSLYKASSRASNGHVDLDWFLAGGQLLEATLAIKQLIRPDHLEDWLNLQCLNLQCLNTLCTYVVQGRPFNHQHHLLMPDIESCRMAILESSDPQLMLALASLLKVMVHYPQWDSICLENASLLTLFSKDGTWIKQGLGWTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MTW2</accession>
    <name>A0A1C7MTW2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">FAR1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_11671</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01002321">
        <property type="protein sequence ID" value="OBZ80280.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MTW2"/>
    <dbReference type="InParanoid" id="A0A1C7MTW2"/>
    <dbReference type="OrthoDB" id="10414689at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="236"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ80280.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="236" mass="27445" checksum="535E0983216F614C" modified="2016-11-30" version="1" fragment="single">MNKNQNIFSDDDDFMEPLPIVPQSKFAVKNNNQLKTVQSNNDYTFVEGGIRLPVTADMKFQNLDSLTDIIFDWAHKEHMILIRSKFEAYRRLYLTCKFSDRSLQQEPGNDAKRQCQTWKRECKFIIRISFKSEGSYWSVLKPFDADEHRHDHPCSKKFNRVVPQGKANLLECKDIKKMVEMVHKNTSIPEIRKNIGTFEGAPILEYQDIANIANEIKESATPNSKIEDAKVLINKM</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MUK2</accession>
    <name>A0A1C7MUK2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_11449</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01002042">
        <property type="protein sequence ID" value="OBZ80502.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MUK2"/>
    <dbReference type="InParanoid" id="A0A1C7MUK2"/>
    <dbReference type="OrthoDB" id="2300279at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="91"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="92"/>
            <end position="103"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ80502.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="150" mass="17192" checksum="773F1AF7AB56AEDA" modified="2016-11-30" version="1">MSVKALFRVVPQKDENNRQIAERWLEALSLVDSERLSVDELLFIVHCGFFPSEWRTKIYNSINSSNENIMGKKFLDMVIWFHDLELPSANKRSAEDVPAERATKNSRQTEVPKENAIAAAEVTRLATIKLAPDKGTEEKKVRLAHPWLTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MV06</accession>
    <name>A0A1C7MV06_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_11695</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01002360">
        <property type="protein sequence ID" value="OBZ80256.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MV06"/>
    <dbReference type="STRING" id="101091.A0A1C7MV06"/>
    <dbReference type="InParanoid" id="A0A1C7MV06"/>
    <dbReference type="OrthoDB" id="2286841at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31912">
        <property type="entry name" value="IP13529P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31912:SF34">
        <property type="entry name" value="NOTOCHORD-RELATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ80256.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="256" mass="29246" checksum="F0F82F2FE7F01149" modified="2016-11-30" version="1">MIQGATEDNKDFPASKLFFKDRGSDSLLALNAFSPDKDIPTEILHTVLLRIAQYLTNDLIKIDANDEELNIIADALDNYKFSEGFSRKFSRQLRHCESFLGKDYKILLQVLPVKLVSHFSESTTHIVKIFHCFAKLGKLYSLLFVQEVSDNFDDYIEQVKESSNELVSALHLYDTVCTVQDYKGYTAKPKVHFLTHIAEGIQRFGTASNFETEKSEQFNKHIREHIHHTNKVDVSKQLATKFGKQSVMRHVIDGGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MW90</accession>
    <name>A0A1C7MW90_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Retrotransposon gag domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_10875</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001472">
        <property type="protein sequence ID" value="OBZ81077.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MW90"/>
    <dbReference type="InParanoid" id="A0A1C7MW90"/>
    <dbReference type="OrthoDB" id="2289027at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005162">
        <property type="entry name" value="Retrotrans_gag_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03732">
        <property type="entry name" value="Retrotrans_gag"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Retrotransposon gag" evidence="1">
        <location>
            <begin position="68"/>
            <end position="121"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03732"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ81077.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="121" mass="13882" checksum="5DD55CFC7D4B5DC1" modified="2016-11-30" version="1">MNGSSPVGGSIQDGVNKDEIKERRCRVQLPSFHSGDMNQARVWLMEYNSLTHHIRFTEKEKLADLEVRFKGDALAWFMYLPEMGKKSWKEFEKVFQDYFGGGASTADMALNELKTLKQGNM</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MWK9</accession>
    <name>A0A1C7MWK9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Iron-sulfur clusters transporter ATM1, mitochondrial</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="14">Iron-sulfur clusters transporter atm1, mitochondrial</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="18" type="primary">atm1</name>
        <name evidence="18" type="ORF">A0J61_10751</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18 19">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="3">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="12">Belongs to the ABC transporter superfamily. ABCB family. Heavy Metal importer (TC 3.A.1.210) subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001366">
        <property type="protein sequence ID" value="OBZ81200.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MWK9"/>
    <dbReference type="FunCoup" id="A0A1C7MWK9">
        <property type="interactions" value="420"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7MWK9"/>
    <dbReference type="InParanoid" id="A0A1C7MWK9"/>
    <dbReference type="OrthoDB" id="6500128at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006879">
        <property type="term" value="P:intracellular iron ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016226">
        <property type="term" value="P:iron-sulfur cluster assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140466">
        <property type="term" value="P:iron-sulfur cluster export from the mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990542">
        <property type="term" value="P:mitochondrial transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd18582">
        <property type="entry name" value="ABC_6TM_ATM1_ABCB7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000299">
        <property type="entry name" value="ABC transporter ATP-binding protein/permease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1560.10:FF:000004">
        <property type="entry name" value="ATP-binding cassette sub-family B member 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="entry name" value="ABC transporter type 1, transmembrane domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039421">
        <property type="entry name" value="Type_1_exporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24221">
        <property type="entry name" value="ATP-BINDING CASSETTE SUB-FAMILY B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24221:SF402">
        <property type="entry name" value="IRON-SULFUR CLUSTERS TRANSPORTER ABCB7, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="ABC transporter transmembrane region"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="11 15" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-1278">Translocase</keyword>
    <keyword evidence="6 15" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10 15" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="228"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="261"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="17">
        <location>
            <begin position="116"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="16">
        <location>
            <begin position="438"/>
            <end position="630"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="18">
        <location>
            <position position="630"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00024363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00039906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00040792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="OBZ81200.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="630" mass="69559" checksum="923760557BE4C023" modified="2016-11-30" version="1" fragment="single">MLPRLSTHCLRATALRQVWKLPPANKALAAPSSIIYKNLASTHKRPANIWSLTQKRIFTSSVNKSTPAKKTIDKNTTPIAESASNKARNATDWAIIRQLMKYIWPKNDAGVKARVVIALSLLVGGKLLNVQVPFFFKNVIDSLNVTMPEDGTLWTVCGAAIIGYGLARLGASAFQELRNAVFAAVAQKAIRRVALNVFSHLHKLDLGFHLTRQTGGLNRAIDRGTKGISFMVSSMVFHVLPTALEISMVCGILAYKFGTPYALVTFGTIVAYTGYTVTTTAWRTKFRKQANAADNVAASKAVDSLINFEAVKYFNNEKFEAEQYDKPLQQYEKASLKVASSLAMLNAGQNAIFSTSLTIMMLLSADGVLKGTMTVGDVVMVNQLVFQLSMPLNFLGSVYRELRQSLIDMDTLFNLENRAPLVQDAPDAKEFVFKGGEIRFENVKFGYHPDRPILNNVSFTVPAGSKAAFVGPSGCGKSTILRLLFRFYEPQSGNIYVDGQNIKDVTMDSLRRAIGVVPQDTTLFNNSIYYNINYGRTDASKEEVYAAAKRARVHDVIMSLPEKYDSTVGERGMMLSGGEKQRISLARTILKNPRILFLDEATSALDTHTEQSLLANFRSILRETGMTSLH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MWR6</accession>
    <name>A0A1C7MWR6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Starch synthase catalytic domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">A0J61_11055</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001632">
        <property type="protein sequence ID" value="OBZ80896.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MWR6"/>
    <dbReference type="STRING" id="101091.A0A1C7MWR6"/>
    <dbReference type="InParanoid" id="A0A1C7MWR6"/>
    <dbReference type="OrthoDB" id="512920at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2000">
        <property type="entry name" value="Glycogen Phosphorylase B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013534">
        <property type="entry name" value="Starch_synth_cat_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08323">
        <property type="entry name" value="Glyco_transf_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="76"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="domain" description="Starch synthase catalytic" evidence="4">
        <location>
            <begin position="137"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="531"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF08323"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OBZ80896.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="531" mass="60388" checksum="A2AF347742D72D06" modified="2016-11-30" version="1" fragment="single">MSPPQIFVSIDQETASPGATLVTGTSTSPSPTTYASKISTTSRISPSSSSFAASFLSSPDTSQPRNLIKYDKKWRWWNILSIFAALLCIAELVFLCASYDLLNQESTSIRFLKRQYPFKTYTHLDTSLPTQIEKGTRVYHVTREFGPATVSELGRTVTALAAAQQASNLTEVAIVMPFYSFMKRLAEREIDMVMDIRGKKPGQMMTVEFRVWKVLYAFNPPVQAPSVYEWQMINNINTSVLLTPQRPPAPTDAVPVYMISHANRKPFNQAFKCRTPSEIYNENELPTEWKDQYFAKAAAAFLAHKATAADEESIFAPIRIVPRVDIVHIHGASNAYVAKILRDKKEADDLGPRPPAIVYTMHDHKEEVQYSNTFRNVTKFLDHLGEREKLRKYVYGSKLFMSKLAIDLADAVTFTSRPIATDIVEGRHDFHMKELVMDDLLRKAENSRLYGINGAIDYYSTEHPFITDKLVSRKMGYPQYGLQLIRDQDSIYSTDPFHPLALNVPNTPTYWTLSEDPNDFISMYKDRAKRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MWU6</accession>
    <name>A0A1C7MWU6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_10658</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001295">
        <property type="protein sequence ID" value="OBZ81292.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MWU6"/>
    <dbReference type="InParanoid" id="A0A1C7MWU6"/>
    <dbReference type="OrthoDB" id="2289822at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ81292.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="210" mass="24466" checksum="2A73F61BAFBA3CAC" modified="2016-11-30" version="1" fragment="single">RTIQKYTNLSKSKSAPHKETDNYIERYNYFKTYNAQLNQQGLIPARRIKNSEFLDHPDDIDQVMPQLWERFAYQCLDQDINIAGVSIKCIEAAMKRYFGRLPNGIARLDNNQVKLTARVRLDDIARESSRSSQVSWYVGQVITYLVHKHGRRVYHLAVISLVEQSDMDEYGVPVVTCFANNEDKKIVVYDVKDIVTPVGFIRFNPNERQF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MXB6</accession>
    <name>A0A1C7MXB6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Presequence translocated-associated motor subunit PAM17</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">PAM17</name>
        <name evidence="13" type="ORF">A0J61_10407</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner.</text>
    </comment>
    <comment type="subunit">
        <text evidence="12">Component of the PAM complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 12">Mitochondrion inner membrane</location>
            <topology evidence="1 12">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 12">Belongs to the PAM17 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001157">
        <property type="protein sequence ID" value="OBZ81545.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MXB6"/>
    <dbReference type="FunCoup" id="A0A1C7MXB6">
        <property type="interactions" value="46"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7MXB6"/>
    <dbReference type="InParanoid" id="A0A1C7MXB6"/>
    <dbReference type="OrthoDB" id="5970083at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001405">
        <property type="term" value="C:PAM complex, Tim23 associated import motor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030150">
        <property type="term" value="P:protein import into mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013875">
        <property type="entry name" value="Pam17"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28021">
        <property type="entry name" value="PRESEQUENCE TRANSLOCATED-ASSOCIATED MOTOR SUBUNIT PAM17, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28021:SF1">
        <property type="entry name" value="PRESEQUENCE TRANSLOCATED-ASSOCIATED MOTOR SUBUNIT PAM17, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08566">
        <property type="entry name" value="Pam17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="10 12" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5 12" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="6 12" id="KW-0653">Protein transport</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="9 12" id="KW-0811">Translocation</keyword>
    <keyword evidence="4 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 12" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="52"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="87"/>
            <end position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU367146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="OBZ81545.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="192" mass="21904" checksum="DAB0ED6538740701" modified="2016-11-30" version="1">MALSPLKTQLLKRPFLATQVRLASQTSVEGQDLLPTWNDYFKLRKKRRAYEVAAYLPSTTGPLVGAFGYFAQMEVDPYTKILGLDPLMGAILCTGAAGFVGFLMSPSVGNVFFKLFNRKYLRVMDQRDKAFYEHIKQNRAPARFNSIRSPIPDYYGEKINSVQGYRNWLRKQREHIRKGTFGGNVNDNPDLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MXI4</accession>
    <name>A0A1C7MXI4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Peptidase M13 C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_10418</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001162">
        <property type="protein sequence ID" value="OBZ81533.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MXI4"/>
    <dbReference type="STRING" id="101091.A0A1C7MXI4"/>
    <dbReference type="InParanoid" id="A0A1C7MXI4"/>
    <dbReference type="OrthoDB" id="6475849at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016485">
        <property type="term" value="P:protein processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.390.10">
        <property type="entry name" value="Collagenase (Catalytic Domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024079">
        <property type="entry name" value="MetalloPept_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000718">
        <property type="entry name" value="Peptidase_M13"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018497">
        <property type="entry name" value="Peptidase_M13_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11733:SF133">
        <property type="entry name" value="PHOSPHATE-REGULATING NEUTRAL ENDOPEPTIDASE PHEX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11733">
        <property type="entry name" value="ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01431">
        <property type="entry name" value="Peptidase_M13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55486">
        <property type="entry name" value="Metalloproteases ('zincins'), catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51885">
        <property type="entry name" value="NEPRILYSIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase M13 C-terminal" evidence="1">
        <location>
            <begin position="3"/>
            <end position="112"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01431"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ81533.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="113" mass="12724" checksum="ED628E6334D1711A" modified="2016-11-30" version="1">MAKTLGENIADIGGLSTAVDAYRKYINKERNGQPEPSLPGLEHLTAEQMLYISFGLFHCESIPPNYANAYDTDFHAPFFARTNPVVRNNENFAAVFNCQADSPMNKKEKCHLW</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MZ00</accession>
    <name>A0A1C7MZ00_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Erythromycin 3''-O-methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">eryG</name>
        <name evidence="2" type="ORF">A0J61_09807</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000942">
        <property type="protein sequence ID" value="OBZ82145.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MZ00"/>
    <dbReference type="STRING" id="101091.A0A1C7MZ00"/>
    <dbReference type="InParanoid" id="A0A1C7MZ00"/>
    <dbReference type="OrthoDB" id="61390at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050723">
        <property type="entry name" value="CFA/CMAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041698">
        <property type="entry name" value="Methyltransf_25"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43667">
        <property type="entry name" value="CYCLOPROPANE-FATTY-ACYL-PHOSPHOLIPID SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43667:SF2">
        <property type="entry name" value="FATTY ACID C-METHYL TRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13649">
        <property type="entry name" value="Methyltransf_25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransferase" evidence="1">
        <location>
            <begin position="63"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="156"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ82145.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="156" mass="17686" checksum="96EEEF0D1CD13BC0" modified="2016-11-30" version="1" fragment="single">MQETQQSELYGLRNLLVNLELPPKSAWFNMGLWDRPNLNYSQACQNLVREVTEQCAIQPNSSILDVGFGCGDSCLFLAEHYQSKVKGITNEQSQLTVANKRIPDHLKEQIALILGSADDLSTYTSSEKHDAVLSIDSAYHFNTRWDFLRNAFDCLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MZ19</accession>
    <name>A0A1C7MZ19_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_10294</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001107">
        <property type="protein sequence ID" value="OBZ81656.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MZ19"/>
    <dbReference type="InParanoid" id="A0A1C7MZ19"/>
    <dbReference type="OrthoDB" id="2222743at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ81656.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="81" mass="8979" checksum="E974C3E8727E9758" modified="2016-11-30" version="1" fragment="single">SLGNLAPRVQNVLGAISNKRNDYSALFRFVIRNNINVFDQATAELNTCFTTFTPASRSSTLQGYYSTIQSAFSSVKADYNM</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MZ31</accession>
    <name>A0A1C7MZ31_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_10285</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001103">
        <property type="protein sequence ID" value="OBZ81666.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MZ31"/>
    <dbReference type="InParanoid" id="A0A1C7MZ31"/>
    <dbReference type="OrthoDB" id="2252305at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ81666.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="247" mass="28678" checksum="A6522157B242985F" modified="2016-11-30" version="1">MDSPYPTAPVMLATSPSPSLQLTIHQQDNYQSLINSKQETVYYLSPKPQETILYDASMKPLGQTHHQNLTVIFQDHTVQLTPLFEFTFENQTYHWQAQHFSCYHSESKALLAQLKDQSILFYNNNPFRPHQFTESLIALIILSSQTLLNACRHNEKEEHDVASLSSVYHYPGHHSLVNPSTIRWSTPQSFKSIELDPGIWRCWWGYGFWWSWFPCCMPGGCCDRACIHIRGGHQTTLSRQGWQQQNY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MZ69</accession>
    <name>A0A1C7MZ69_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Heat shock factor protein 4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">HSF4</name>
        <name evidence="10" type="ORF">A0J61_09833</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the HSF family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000950">
        <property type="protein sequence ID" value="OBZ82117.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MZ69"/>
    <dbReference type="STRING" id="101091.A0A1C7MZ69"/>
    <dbReference type="InParanoid" id="A0A1C7MZ69"/>
    <dbReference type="OrthoDB" id="60033at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.10:FF:000027">
        <property type="entry name" value="Heat shock transcription factor 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000232">
        <property type="entry name" value="HSF_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10015:SF427">
        <property type="entry name" value="HEAT SHOCK FACTOR PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10015">
        <property type="entry name" value="HEAT SHOCK TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00447">
        <property type="entry name" value="HSF_DNA-bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00056">
        <property type="entry name" value="HSFDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00415">
        <property type="entry name" value="HSF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00434">
        <property type="entry name" value="HSF_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0346">Stress response</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HSF-type DNA-binding" evidence="9">
        <location>
            <begin position="99"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="17"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="22"/>
            <end position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006403"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU004020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OBZ82117.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="243" mass="28290" checksum="AAE3B2CC6F0B316C" modified="2016-11-30" version="1">MSNPFFTVPPFDPYSLPPHRNSASSTASSQHSSSPFNHNLEMSSDLEEDKTTSKKGTSTFISKLYSMVNDDRNQHLIFWNPSGTSFLICNASRFSREILPEHFKHANFSSFVRQLNMYGFHKINKSSRVHRGSQNNNSENEFWEFSHPKFQQDKPELLEEIRRKAMDSEQLRREAGDMQASFAMIQLSQAELLQQFRALKQDYTRLLQVVDEMKQVQLQQQWLIRKLAENQGLTMSQLPCEFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MZD8</accession>
    <name>A0A1C7MZD8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="20">chitin deacetylase</fullName>
            <ecNumber evidence="20">3.5.1.41</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="24" type="primary">CDA_2</name>
        <name evidence="24" type="ORF">A0J61_09808</name>
    </gene>
    <organism evidence="24 25">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="24 25" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="24 25">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="21">
            <text>[(1-&gt;4)-N-acetyl-beta-D-glucosaminyl](n) + n H2O = chitosan + n acetate</text>
            <dbReference type="Rhea" id="RHEA:10464"/>
            <dbReference type="Rhea" id="RHEA-COMP:9593"/>
            <dbReference type="Rhea" id="RHEA-COMP:9597"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:17029"/>
            <dbReference type="ChEBI" id="CHEBI:30089"/>
            <dbReference type="ChEBI" id="CHEBI:57704"/>
            <dbReference type="EC" id="3.5.1.41"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="21">
            <dbReference type="Rhea" id="RHEA:10465"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Co(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:48828"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cell membrane</location>
            <topology evidence="3">Lipid-anchor</topology>
            <topology evidence="3">GPI-anchor</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Secreted</location>
            <location evidence="2">Cell wall</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the polysaccharide deacetylase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="24">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.5.1.41" evidence="20"/>
    <dbReference type="EMBL" id="LUGH01000943">
        <property type="protein sequence ID" value="OBZ82142.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MZD8"/>
    <dbReference type="STRING" id="101091.A0A1C7MZD8"/>
    <dbReference type="InParanoid" id="A0A1C7MZD8"/>
    <dbReference type="OrthoDB" id="407355at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098552">
        <property type="term" value="C:side of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004099">
        <property type="term" value="F:chitin deacetylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006032">
        <property type="term" value="P:chitin catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009272">
        <property type="term" value="P:fungal-type cell wall biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000272">
        <property type="term" value="P:polysaccharide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd10952">
        <property type="entry name" value="CE4_MrCDA_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.370:FF:000004">
        <property type="entry name" value="Related to Chitin deacetylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.370">
        <property type="entry name" value="Glycoside hydrolase/deacetylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011330">
        <property type="entry name" value="Glyco_hydro/deAcase_b/a-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002509">
        <property type="entry name" value="NODB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050248">
        <property type="entry name" value="Polysacc_deacetylase_ArnD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10587:SF98">
        <property type="entry name" value="CHITIN DEACETYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10587">
        <property type="entry name" value="GLYCOSYL TRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01522">
        <property type="entry name" value="Polysacc_deac_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88713">
        <property type="entry name" value="Glycoside hydrolase/deacetylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51677">
        <property type="entry name" value="NODB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="15" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="5" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6" id="KW-0134">Cell wall</keyword>
    <keyword evidence="18" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="12" id="KW-0146">Chitin degradation</keyword>
    <keyword evidence="16" id="KW-0170">Cobalt</keyword>
    <keyword evidence="14" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="8" id="KW-0336">GPI-anchor</keyword>
    <keyword evidence="11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="17" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="13" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="19" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="25" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0964">Secreted</keyword>
    <keyword evidence="10 22" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="22">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008889379" description="chitin deacetylase" evidence="22">
        <location>
            <begin position="22"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="domain" description="NodB homology" evidence="23">
        <location>
            <begin position="158"/>
            <end position="351"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010973"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022512"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022622"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="ARBA" id="ARBA00024056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="21">
        <source>
            <dbReference type="ARBA" id="ARBA00048494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="22">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="23">
        <source>
            <dbReference type="PROSITE" id="PS51677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="24">
        <source>
            <dbReference type="EMBL" id="OBZ82142.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="25">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="449" mass="48829" checksum="2B8A054786F2EE4F" modified="2016-11-30" version="1">MHIKTLTISVAIAKFIAFASADVNISTYYQSLESKIDPKNATVPSIEQTTSLDPSVECKDYTPDSSLIAINRSEFPESWSIATSNGRADSAEFTSLYNSIDWTKAPNISVRTIKSNGDLNDSGYDYDTDPDCWWSATTCTVPKLADVNPDIYKCDEPETWGLTYDDGPNCSHNAFYDYLQQNNLKASMFYIGSNVLDLPYGALRGIADGHHIASHTWSHPYMTTLTNKEVLAELYYTQKAIKLATGITPRYWRPPYGDVDDRVRWVATQLGMTAIIWNYDTDDWAADDGSTPAAVEKTYEQFIEMGSNGTFADSGNIVLTHEIDNITMSLALEFLPKIKASYKNVLDVATCANITRPYFEDFEWTSVINGTGASNTASVANATSTVVVAATSSVADTSSTAEATSTTTTGDASSTGLVAAAQVQQVANNAHLNTPSLALAAGFIVSLIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MZI3</accession>
    <name>A0A1C7MZI3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_10115</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001040">
        <property type="protein sequence ID" value="OBZ81836.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MZI3"/>
    <dbReference type="InParanoid" id="A0A1C7MZI3"/>
    <dbReference type="OrthoDB" id="10365777at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ81836.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="441" mass="50199" checksum="EA5B48B0640084B9" modified="2016-11-30" version="1">MPSIISENVKSAIQLYLQEKKKANEDASVYSFVNTHVELVRTARDLMPNYQLFIRRTLQSIAKGLEMKVVETSITRWRKLLDSDAETTISTIPTVSTISSSGVSVRQVVTDISQWKVSISNKQLMVKGVGVEALFNEFKQQSYNAVMNNDPSVSIQEIAALDNILILENLKDSSRLVKEIFGSTPLHELRLDQQKPYKEIKDKFPSEIKDDIEEILDEYSKENDLYEADKRIGTLYSKAEDHDVFRIIKCVANLLDEVSEEELVVSENHLTASFIHVIMKAIFKKDTKIFPHMSNHKAGDSSWRPDYKVSRVQEGRARQECFGEVKPFSCKDSSNKAKDIIKAIKYSKKAIMKFKYNFLITFVAQNDVLRFFVTRHLSDTMFVAAQVESFKLPTTTSEISQIGLTLTKLLRLSKLHSTCQPNAISVKEDVDLSESVIDSLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-06-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MZL9</accession>
    <name>A0A1C7MZL9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_09762</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000930">
        <property type="protein sequence ID" value="OBZ82188.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MZL9"/>
    <dbReference type="InParanoid" id="A0A1C7MZL9"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ82188.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="76" mass="8749" checksum="65CF1E369BF76102" modified="2016-11-30" version="1">MISFIPSSCRKHVSTRLLMVGRKFMKSTSVRALQNDQKKEAVTVVTATTTTTNDVPYLNHKHKKVSFRHSTLIIWF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MZT7</accession>
    <name>A0A1C7MZT7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">ATP-dependent DNA helicase</fullName>
            <ecNumber evidence="1">5.6.2.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_09621</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="5.6.2.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the helicase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.6.2.3" evidence="1"/>
    <dbReference type="EMBL" id="LUGH01000892">
        <property type="protein sequence ID" value="OBZ82333.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7MZT7"/>
    <dbReference type="InParanoid" id="A0A1C7MZT7"/>
    <dbReference type="OrthoDB" id="5860629at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043139">
        <property type="term" value="F:5'-3' DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000723">
        <property type="term" value="P:telomere maintenance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010285">
        <property type="entry name" value="DNA_helicase_pif1-like_DEAD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10492">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10492:SF57">
        <property type="entry name" value="ATP-DEPENDENT DNA HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05970">
        <property type="entry name" value="PIF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0227">DNA damage</keyword>
    <keyword evidence="1" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="1" id="KW-0234">DNA repair</keyword>
    <keyword evidence="1" id="KW-0347">Helicase</keyword>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA helicase Pif1-like DEAD-box helicase" evidence="2">
        <location>
            <begin position="141"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU363044"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF05970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ82333.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="252" mass="28407" checksum="438C2DCEDA6D0EE3" modified="2016-11-30" version="1" fragment="single">NQWKECLEEAAHTQSPVSLRKLFCIIFVFCDPADPYQLWLDFKDKLSEDHWYQLHNHPVFDPTVDDIHKKACNCALLDIEDILQRHYGTSLQWYDQFQLPSVDCRIDHISSPLSSLIRQQLQLNSAARQTDFSKDITNFDEGQHHAFDAIMHCVQKDDCTSTEFPRVFFVDGPGGTGKTCXFSTLLKAVRSTDDWFALAVASSGTATLLLDGSRTAHSLLKIPPGTSSTTMCGIKHSSSEVELLKNKTHHLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N031</accession>
    <name>A0A1C7N031_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">mannose-1-phosphate guanylyltransferase</fullName>
            <ecNumber evidence="3">2.7.7.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">mpg1_0</name>
        <name evidence="13" type="ORF">A0J61_09517</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>alpha-D-mannose 1-phosphate + GTP + H(+) = GDP-alpha-D-mannose + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:15229"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:57527"/>
            <dbReference type="ChEBI" id="CHEBI:58409"/>
            <dbReference type="EC" id="2.7.7.13"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Nucleotide-sugar biosynthesis; GDP-alpha-D-mannose biosynthesis; GDP-alpha-D-mannose from alpha-D-mannose 1-phosphate (GTP route): step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the transferase hexapeptide repeat family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.13" evidence="3"/>
    <dbReference type="EMBL" id="LUGH01000868">
        <property type="protein sequence ID" value="OBZ82433.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N031"/>
    <dbReference type="FunCoup" id="A0A1C7N031">
        <property type="interactions" value="375"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N031"/>
    <dbReference type="InParanoid" id="A0A1C7N031"/>
    <dbReference type="OrthoDB" id="2435509at2759"/>
    <dbReference type="UniPathway" id="UPA00126">
        <property type="reaction ID" value="UER00930"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004475">
        <property type="term" value="F:mannose-1-phosphate guanylyltransferase (GTP) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009298">
        <property type="term" value="P:GDP-mannose biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd06425">
        <property type="entry name" value="M1P_guanylylT_B_like_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.550.10:FF:000013">
        <property type="entry name" value="mannose-1-phosphate guanyltransferase beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.10.10">
        <property type="entry name" value="Hexapeptide repeat proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="entry name" value="Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055561">
        <property type="entry name" value="DUF7137"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056729">
        <property type="entry name" value="GMPPB_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045233">
        <property type="entry name" value="GMPPB_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050486">
        <property type="entry name" value="Mannose-1P_guanyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005835">
        <property type="entry name" value="NTP_transferase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22572">
        <property type="entry name" value="SUGAR-1-PHOSPHATE GUANYL TRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23585">
        <property type="entry name" value="DUF7137"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25087">
        <property type="entry name" value="GMPPB_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00483">
        <property type="entry name" value="NTP_transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="6" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 13" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="DUF7137" evidence="11">
        <location>
            <begin position="74"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="domain" description="Nucleotidyl transferase" evidence="10">
        <location>
            <begin position="228"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="domain" description="Mannose-1-phosphate guanyltransferase C-terminal" evidence="12">
        <location>
            <begin position="473"/>
            <end position="581"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="20"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00047343"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF23585"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF25087"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="OBZ82433.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="582" mass="63482" checksum="F61FC53357E78407" modified="2016-11-30" version="1">MKRAEEAASIQPPPASSQPTNLPQPLASNSTNATPTQSVNGTLHTNSTQTNATQSANGNPFAGKPTFASFSNDIPPAYLTWKKPIPNQTFPPLFKIGVSNITFEWTVDPNVLKVQPENLTVALANPQKQTLTAAIVPGTATSAVWDLAHLPPGSPLMVGYYTVWVHDQRGPKAYPSPGWLMPDSRLIVAMYSTESYVGRTDSMFCPTCYLGAGASFRESLLPLLTTFGFGTRLRPLTLTLPKPLVEFANKPMILHQIENLAKAGVTDIVLAVNYRPEIMVAALKEYEAIYNVKITFSVETEPLGTAGPLALARDILAKDDSPFFVLNSDVICDYPFEQLRDFHQSHGGEGTITVTKVDDPSKYGVVVNCSSSSSVIERFVEKPKEFISNKINAGMYILNPSVLDRIELKPMSIEKEVFPFIAEAGQLHTFDLDGFWMDVGQPKDFLTGTCLYLSHLSKKAPETLTQQADFVHKGNVLIHPTAKVGKDCRIGPNVVIGPNVVVGDGVRLQRCVILEGVEVKDFAWVNSSIIGWHSSIGRWSRIEGCSVLGDDVTVNDEIYINGGSILPHKGISSNITEPQIIM</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N0A7</accession>
    <name>A0A1C7N0A7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Transcription factor domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">A0J61_09426</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000847">
        <property type="protein sequence ID" value="OBZ82527.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N0A7"/>
    <dbReference type="InParanoid" id="A0A1C7N0A7"/>
    <dbReference type="OrthoDB" id="2369992at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050815">
        <property type="entry name" value="TF_fung"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47338:SF5">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47338">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="3"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="474"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OBZ82527.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="474" mass="54250" checksum="A5CD6D5452AF50A8" modified="2016-11-30" version="1" fragment="single">MYYHHAHGAVVQLREDLESLEKELAAFREPSQQHMRWQLQFKNGQLSLLSQIKSLQEFLVYGKAALSYLSPFRDIMSASWPQNQTSFLQPAIQQLLQNEQSHPCNRLTILNDASDTLVWRAPQRMMFPLINHYFKCCNATLPILHENSYRKHLASLIDPLQDPVVNAICASACISQCKHAFLTSREKRRLGEYYFQQSTELLLDIFDDIDKRLDTLLTINLLQPFMLATLRVSESKKWNTIGIAIALDLTRQPVTVCTYLDRVRQAIIARNRILIFVSAHTLDFYAEGKCIDIPAVRLKFDILPDDCDRTKETLEVINCISQFLFCPSYIRIANHVRAMSVGRPAEIRLEDVVYSEEAILSWWQQLPNHLKLSDTLNSFTQDLVHGCGSILKLTIAISSLILIMSIETALLSSISVNQQQHGAQTSFYQRAFETMSYSVDISILIIRQLDRLGFCSSPVRLLAKMMDYIASLVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N0G2</accession>
    <name>A0A1C7N0G2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_09377</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000835">
        <property type="protein sequence ID" value="OBZ82573.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N0G2"/>
    <dbReference type="InParanoid" id="A0A1C7N0G2"/>
    <dbReference type="OrthoDB" id="5597211at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058940">
        <property type="entry name" value="mS26_fungi"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26163">
        <property type="entry name" value="mS26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="57"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="110"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="65"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ82573.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="240" mass="27610" checksum="815BF9CBF2F66870" modified="2016-11-30" version="1">MSTIARIARINLPSRSLVRLASTQYVPGRKGYAPGFEAPEGTREETKVIIKRRDIGNSLTSHLESQSPKSQSSTSPKKQYRQALRVTRHKYAHELLEKQGQKQLQSAEKLAMAEQKADAVKRALEAEKRQQKEHVQEVVQMLDLKQTEQQSSQDRNQRRVENRIQFEEQQRLVRRKQLLKLYAATDAFVTLDNLDAKIDAVMSSEGRSFHPSFDELMHSTSSVQNEIEQRKQQLKEVMGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N0K4</accession>
    <name>A0A1C7N0K4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Ankyrin repeat domain-containing protein 54</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">ANKRD54_0</name>
        <name evidence="5" type="ORF">A0J61_09425</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000847">
        <property type="protein sequence ID" value="OBZ82528.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N0K4"/>
    <dbReference type="STRING" id="101091.A0A1C7N0K4"/>
    <dbReference type="InParanoid" id="A0A1C7N0K4"/>
    <dbReference type="OrthoDB" id="194358at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24126:SF14">
        <property type="entry name" value="ANK_REP_REGION DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24126">
        <property type="entry name" value="ANKYRIN REPEAT, PH AND SEC7 DOMAIN CONTAINING PROTEIN SECG-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="177"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="410"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="410"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="427"/>
            <end position="436"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OBZ82528.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="436" mass="49103" checksum="24012FE3858A1B16" modified="2016-11-30" version="1">MPTLFSKTFTLLNNIKPPTIESSNVNRQSRDAPFDLSESPREIDHYESLRSDKDDVVIELAESPKPSLSIWKAAEQNDLKSLTYYIDHAPLETSTLLNTRDPDTDCTLLHLLIANASDASDIFPALTLLLKHGADATARNVYNVQAVHMISLHYNKPLPAMQQLLAHHANPNARDGDGWTPLHYAARFCSNPHAVLQLLIEHGAHINSTDAGNKTPLFGLLANNDLVQAFEYLIVQAKADLSIRGDFLDPVNRNVRQGSVVLQAVKYRRLECLEFLIKSQMAFQQLKQVLDKEELDYANQMVKEQQLRLTTDQEVAKSELILQLLQELEDQLERDGSSLFAMKANQTTSIITNGHQTTQGTANRSQLQHKSSSFVGAMLDHMRNKTTVQRKSSVPNRILRKVSLMLQRSKSESSEISSLKRVEEELYNTSNRLPDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N0L1</accession>
    <name>A0A1C7N0L1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_09327</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000825">
        <property type="protein sequence ID" value="OBZ82627.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N0L1"/>
    <dbReference type="InParanoid" id="A0A1C7N0L1"/>
    <dbReference type="OrthoDB" id="10530121at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="35"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="62"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="99"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ82627.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="99" mass="11528" checksum="587A40F136D8E7F6" modified="2016-11-30" version="1" fragment="single">MAHKEQRRNSLDFPSSPPPENAKYNALYSLDSHQHSWSETTNTPSHETEESSFNKTSPLVRHMKELGDVQDKTSRKRMHQDNTCQEHKRIRNDKIIASP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N0L6</accession>
    <name>A0A1C7N0L6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">FAM192A/Fyv6 N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">A0J61_09268</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000812">
        <property type="protein sequence ID" value="OBZ82685.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N0L6"/>
    <dbReference type="STRING" id="101091.A0A1C7N0L6"/>
    <dbReference type="InParanoid" id="A0A1C7N0L6"/>
    <dbReference type="OrthoDB" id="75720at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039845">
        <property type="entry name" value="FAM192A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019331">
        <property type="entry name" value="FAM192A/Fyv6_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13495">
        <property type="entry name" value="NEFA-INTERACTING NUCLEAR PROTEIN NIP30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13495:SF0">
        <property type="entry name" value="PSME3-INTERACTING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10187">
        <property type="entry name" value="FAM192A_Fyv6_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAM192A/Fyv6 N-terminal" evidence="4">
        <location>
            <begin position="25"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="147"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="164"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="200"/>
            <end position="209"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF10187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OBZ82685.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="219" mass="25028" checksum="A80305ECD9261E03" modified="2016-11-30" version="1">MSFNIKSSFVSRAVVEANTETQISTDVKESSSASNEVYDPRTLYERLQEQKAIKEEKFFEESRFANQIKRVNEEEAEYFKILADEKEKVESQRRLSERLELEEYRMAVESAKSTPSVAAPVLDEKKKISFSKPNKLVKNNQLKKGALFVKKRRQEDSSSDEENVEKKSPEKKLKVTNEKSNEEANEKSNEKTSEKPKVPASASLSLLSAYSDIPSSDEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N0N0</accession>
    <name>A0A1C7N0N0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Nucleosome assembly protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">A0J61_09357</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the nucleosome assembly protein (NAP) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000831">
        <property type="protein sequence ID" value="OBZ82591.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N0N0"/>
    <dbReference type="FunCoup" id="A0A1C7N0N0">
        <property type="interactions" value="440"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N0N0"/>
    <dbReference type="InParanoid" id="A0A1C7N0N0"/>
    <dbReference type="OrthoDB" id="27325at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006334">
        <property type="term" value="P:nucleosome assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1120.90:FF:000003">
        <property type="entry name" value="Nucleosome assembly protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.5.1500:FF:000001">
        <property type="entry name" value="Nucleosome assembly protein 1-like 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.1500">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1120.90">
        <property type="entry name" value="Nucleosome assembly protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037231">
        <property type="entry name" value="NAP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002164">
        <property type="entry name" value="NAP_family"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11875">
        <property type="entry name" value="TESTIS-SPECIFIC Y-ENCODED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00956">
        <property type="entry name" value="NAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143113">
        <property type="entry name" value="NAP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="132"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="296"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="351"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="141"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="151"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="303"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="351"/>
            <end position="386"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003876"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OBZ82591.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="400" mass="45589" checksum="9089124D523B45FC" modified="2016-11-30" version="1">MEAVEIKNKKITAPTPQNTPINTAPINSQFNPSVPAITEEMETITTPGAAAANPALMNMLQGKLGNLLGEPLPASVQRRINGLKYLQSKHTELEGKFQEEVLALEKKYLELYRPLYTKRAEVVSGQYEPTEEEVAIGAKVDEEDDEEEGEAEKQEKEKKMDEDEEETPVTGIPEFWLTALKTHPQIGDTISEEDCEALKHLVDIRMTYLEKPGFRLEFEFAENDFFTDKILTKTYHYQDNISGGDYVYDFAEGCEIHWKDGKDLTVTVETKKQRHKGTNKTRVVKRTVPAETFFNFFSPPTIPEDENELDEEEAEGLDAKLEADYEMGEEFKEKIIPHAVDFFTGKALEYEDYDDEDDFEDDFLTDEDNEDDDEDDEDDDDDDDDAQPAKGENAPECKQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N258</accession>
    <name>A0A1C7N258_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">VCP-like ATPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">vat</name>
        <name evidence="5" type="ORF">A0J61_08759</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the AAA ATPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000705">
        <property type="protein sequence ID" value="OBZ83192.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N258"/>
    <dbReference type="STRING" id="101091.A0A1C7N258"/>
    <dbReference type="InParanoid" id="A0A1C7N258"/>
    <dbReference type="OrthoDB" id="5421at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000661">
        <property type="entry name" value="calmodulin-interacting protein 111 isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050168">
        <property type="entry name" value="AAA_ATPase_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041569">
        <property type="entry name" value="AAA_lid_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003960">
        <property type="entry name" value="ATPase_AAA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23077">
        <property type="entry name" value="AAA-FAMILY ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23077:SF27">
        <property type="entry name" value="ATPASE FAMILY GENE 2 PROTEIN HOMOLOG A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17862">
        <property type="entry name" value="AAA_lid_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00674">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="4">
        <location>
            <begin position="406"/>
            <end position="546"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OBZ83192.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="642" mass="71812" checksum="89FE4B7AA31009FC" modified="2016-11-30" version="1">MGYQRIDNVEPNLFATKIGIEIHTKALITCSIKHLVRRRLYGRVLKKGDRAEWNICGNNITCMITEVEGISQKAGHSTEYSFQQPRSCDPLTMAEQKDIYITSLTDMIRSSLESSGAYSQLNIPVAKSVLIHGASDLCRRVSRVLSCAIHELSCHELLSFSDEEYGLDSFKAYNPLSLLIKNVSQAAVPSLIVLRDLDLLTPKYAGEKLKTITAIISACVDKISSSNAPINLIGIARDLKQLPDAYRKTDIFRQHMLLPIPSLPQRKQLLTYFLNSTKLKGSIEEDSMDDHITQISLRTSGYVARDLERLIRLAKLKSMRSRDVVDQFKALSLEPNSLSSLEWTDIEYALDTYKPSQKQLEQIESTMPKRTWNDLGGYQAVKDKMKQAVLLPLLQPEVFKKLGIKPPSGLLLYGPSGCGKTALVQALVSESMMNVISIKGPEIFSKYLGETEGRLRKIFATAKRISPCLIFIDEMDAIGTKRGFDMGSGGGGVNERVLSTLLNEMDGVEGRQGVVVVGCTNRPDQIDDAILRPGRLDQLIYIELPSLSDRIDIINTIMKRTSVADDIHPEELAKQTEFCTGADLENLFREAGTVALRDNLNAEYITNKHIQNVLTSVCERAENQVLQGNLDVYERLRHRQFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N2N8</accession>
    <name>A0A1C7N2N8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Putative sentrin-specific protease 8</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">senp8</name>
        <name evidence="6" type="ORF">A0J61_09008</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase C48 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000754">
        <property type="protein sequence ID" value="OBZ82946.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N2N8"/>
    <dbReference type="FunCoup" id="A0A1C7N2N8">
        <property type="interactions" value="1"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N2N8"/>
    <dbReference type="InParanoid" id="A0A1C7N2N8"/>
    <dbReference type="OrthoDB" id="5065855at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008234">
        <property type="term" value="F:cysteine-type peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019784">
        <property type="term" value="F:deNEDDylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000338">
        <property type="term" value="P:protein deneddylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.395.10">
        <property type="entry name" value="Adenoviral Proteinase, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044613">
        <property type="entry name" value="Nep1/2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003653">
        <property type="entry name" value="Peptidase_C48_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46468">
        <property type="entry name" value="SENTRIN-SPECIFIC PROTEASE 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46468:SF1">
        <property type="entry name" value="SENTRIN-SPECIFIC PROTEASE 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02902">
        <property type="entry name" value="Peptidase_C48"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50600">
        <property type="entry name" value="ULP_PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 6" id="KW-0645">Protease</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0788">Thiol protease</keyword>
    <feature type="domain" description="Ubiquitin-like protease family profile" evidence="5">
        <location>
            <begin position="13"/>
            <end position="175"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50600"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OBZ82946.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="238" mass="27562" checksum="44B6D3ACD9DE0F56" modified="2016-11-30" version="1">MTENQIVLHYHDVVIRQSDLDTLSPGQWLNDTMIEFHMEFLERTFVPKDANYLFLRPGMVHLLTYSEGDVMQLESVLPANLDSYEAIFIPVNDGKPHEAYSGTHWALLVYLKSIHTFFYYDTLRYNNLRDAELTSKRLRPLLKTDKKFSFIPSSTPQQDNGSDCGVYVVSMIEYTLRQLLNSRGKENVQYNKVMVLKPKEMATPKQVRDNINGMIKRLQHRSQSLAQTPPVQSNGLME</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N2P7</accession>
    <name>A0A1C7N2P7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_08554</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000670">
        <property type="protein sequence ID" value="OBZ83393.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N2P7"/>
    <dbReference type="STRING" id="101091.A0A1C7N2P7"/>
    <dbReference type="InParanoid" id="A0A1C7N2P7"/>
    <dbReference type="OrthoDB" id="2538345at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34689">
        <property type="entry name" value="NUCLEIC ACID-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34689:SF1">
        <property type="entry name" value="NUCLEIC ACID-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="57"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="280"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="60"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ83393.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="299" mass="34696" checksum="2FE392545307F8ED" modified="2016-11-30" version="1" fragment="single">SSRQIVMLLAILHRDKWVRMIAVTFSLWLPLQVEDLLHLLVPLGTDLDARSLLNTEEEEKAARDHQEDEAAPDRQEDTAVPDRQDGIRRNTLAVAHTIDTQRANIDTLPTHHLTQALHILQKKKIASESVESIKNTKKIRATKNQRLKKSKKSKLASVGDQWGKYAWLIEVKNVNVETIGNSKRKELFADFMEDYNTATMPHEKFYNLHNWEKRQAALRMGEQPVPMSDTFDFKNDEERLRMQHRQAARASASRQPMLQLSEEKIKELARVNRERIEADRMRKMGLTPKEGMGVRYEDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N2R9</accession>
    <name>A0A1C7N2R9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Microphthalmia-associated transcription factor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">Mitf_1</name>
        <name evidence="8" type="ORF">A0J61_08509</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000662">
        <property type="protein sequence ID" value="OBZ83445.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N2R9"/>
    <dbReference type="FunCoup" id="A0A1C7N2R9">
        <property type="interactions" value="1"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N2R9"/>
    <dbReference type="InParanoid" id="A0A1C7N2R9"/>
    <dbReference type="OrthoDB" id="690068at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.280.10">
        <property type="entry name" value="Helix-loop-helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011598">
        <property type="entry name" value="bHLH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036638">
        <property type="entry name" value="HLH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051732">
        <property type="entry name" value="USF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46117">
        <property type="entry name" value="FI24210P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46117:SF3">
        <property type="entry name" value="FI24210P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00010">
        <property type="entry name" value="HLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00353">
        <property type="entry name" value="HLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47459">
        <property type="entry name" value="HLH, helix-loop-helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50888">
        <property type="entry name" value="BHLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="BHLH" evidence="7">
        <location>
            <begin position="200"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="249"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="13"/>
            <end position="32"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50888"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OBZ83445.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="285" mass="32650" checksum="D7C8589D4BA8764A" modified="2016-11-30" version="1">MSQQPEQPLKLKNPTSYHLMQTNGSYGNSQSPHPLAPTLSPFHFTKDSPSEHPQSQIEFHDSFSQHMMHPISSPLSSEYEDHTEYQHLYDRSSFSSSTMPTTIPMDIHRRSSNATDISLQNNGHPTQPPLFVPGSSFESTHSLAMSAPANMGYEYNYHQHPLGLETTPTPGNTSHGLAKSYEDDYTAQLNMQMMMEKRRRRRESHNAVERRRRDNINDRIQELCSLLPDAALENTNLGPNNKPNKGVILKKSVDHIRQLQQEVQSYHQRVADLENTLKMYQQQKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N2W9</accession>
    <name>A0A1C7N2W9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Histone chaperone RTT106/FACT complex subunit SPT16-like middle domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">A0J61_08579</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the RTT106 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000674">
        <property type="protein sequence ID" value="OBZ83371.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N2W9"/>
    <dbReference type="FunCoup" id="A0A1C7N2W9">
        <property type="interactions" value="92"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N2W9"/>
    <dbReference type="InParanoid" id="A0A1C7N2W9"/>
    <dbReference type="OrthoDB" id="75754at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042393">
        <property type="term" value="F:histone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031491">
        <property type="term" value="F:nucleosome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013719">
        <property type="entry name" value="RTT106/SPT16-like_middle_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050454">
        <property type="entry name" value="RTT106/SSRP1_HistChap/FACT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45849">
        <property type="entry name" value="FACT COMPLEX SUBUNIT SSRP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45849:SF3">
        <property type="entry name" value="HISTONE CHAPERONE RTT106"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08512">
        <property type="entry name" value="Rttp106-like_middle"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01287">
        <property type="entry name" value="Rtt106"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Histone chaperone RTT106/FACT complex subunit SPT16-like middle" evidence="3">
        <location>
            <begin position="208"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="313"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="313"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="341"/>
            <end position="403"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM01287"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OBZ83371.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="403" mass="46016" checksum="B331F3EA2E731F6C" modified="2016-11-30" version="1">MPSWLEQNIQDNDLKKSVEHLIESCPESSTVIERIVNYLNSKNDGYMNDGQQISKKRKIDIDPPSDLPCLKIKDVSFQSPARKKFDILIGNTYFHLQNSKTEEIEYRYTLDQFSSIGGACVPTPDKATKCFTFVLFLKDEDCIIFTTQEKGAIAYTHASSDQILDTPDKHINLANLLTKYTHLPIIQPSEDYFHAKGVSSSTGKQEDRTHVVAYLKAKDGYLFFLPTGILFGFKKPTLFFPKESLASNVITGVTQRTFDLTLTLKPNGQILGTGIKTTREEDLETVQFSMIEQSEYGRIDAYTKRLGLDDQSMDEKLKAPVKPKKDDDEQETNDKGKQVDNYEDSDENDDEFEPSDDDSDPLEYDSEAEEEEGEEFNDEMEDVEDRDEVEDEEERDLLEDESD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N427</accession>
    <name>A0A1C7N427_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_08540</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000667">
        <property type="protein sequence ID" value="OBZ83416.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N427"/>
    <dbReference type="STRING" id="101091.A0A1C7N427"/>
    <dbReference type="InParanoid" id="A0A1C7N427"/>
    <dbReference type="OrthoDB" id="2020070at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00761">
        <property type="entry name" value="Glyco_tranf_GTA_type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="47"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="336"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ83416.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="336" mass="39127" checksum="C71FA28F57346E56" modified="2016-11-30" version="1" fragment="single">MAFEEDDLERAGTRSRRQSSWKSPSLPSPEDHQKTSRHVFLFSWKKTVLIILLFFSLTFFFTAHRPRKTSKKPHMIQFEESIVYPDAFELAKKTAFFPLDKKAHVTLQSTAIVREGHTFDQLRRLANQGYTQKQHVPVTAMIHATTPSQLYFQLQAVLAQTALPEHVWIVCSPETEREVEARIMPLDRRRVRVMVLSETDRLSWIKVAKQAATEYVWLLDQDVTPGKRYLEYLLKLYHTPVFQSTLLGTEAMLSQPSFVCFPYQQQQQQQQRTRQVDAINDSWLLHRSWIWTLVAAMDHTEHTLPSVFISQTLWMAAGIPSIVLPTDPIERAYWGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N4D7</accession>
    <name>A0A1C7N4D7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Phospholipid/glycerol acyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_08414</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000644">
        <property type="protein sequence ID" value="OBZ83536.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N4D7"/>
    <dbReference type="STRING" id="101091.A0A1C7N4D7"/>
    <dbReference type="InParanoid" id="A0A1C7N4D7"/>
    <dbReference type="OrthoDB" id="189226at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016746">
        <property type="term" value="F:acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036149">
        <property type="term" value="P:phosphatidylinositol acyl-chain remodeling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002123">
        <property type="entry name" value="Plipid/glycerol_acylTrfase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10983">
        <property type="entry name" value="1-ACYLGLYCEROL-3-PHOSPHATE ACYLTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10983:SF16">
        <property type="entry name" value="LYSOCARDIOLIPIN ACYLTRANSFERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01553">
        <property type="entry name" value="Acyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="15"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="domain" description="Phospholipid/glycerol acyltransferase" evidence="2">
        <location>
            <begin position="114"/>
            <end position="159"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ83536.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="160" mass="18616" checksum="1326B90CA8524A9D" modified="2016-11-30" version="1">MNAIRSVYNGLGCSILLWGHSTLLVAIQWLSVFIWPFSTQWYYKFHAHLMRQWAQNLFQVMHMFAPGELVITFDKSCTEGDSLFVEPEESQEALLERILTRNKYGEVIGVSFPEKLIMIANHQIYADWIYIWFLAYLSKAHGALKIMLKYSLSLVPVYGM</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N4R5</accession>
    <name>A0A1C7N4R5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Survival Motor Neuron Gemin2-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_07949</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000570">
        <property type="protein sequence ID" value="OBZ84008.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N4R5"/>
    <dbReference type="STRING" id="101091.A0A1C7N4R5"/>
    <dbReference type="InParanoid" id="A0A1C7N4R5"/>
    <dbReference type="OrthoDB" id="197400at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd22851">
        <property type="entry name" value="SMN_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049481">
        <property type="entry name" value="SMN_G2-BD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20636">
        <property type="entry name" value="SMN_G2-BD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Survival Motor Neuron Gemin2-binding" evidence="2">
        <location>
            <begin position="16"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="41"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="41"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="51"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="82"/>
            <end position="94"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF20636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ84008.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="94" mass="10964" checksum="85196298C6C8554C" modified="2016-11-30" version="1">MDELAIGTVLYTQGDAKHEDIWDDTELIEHWDRSIEAYRQMQSTQGNKPIQQKHKVVKKTPKRKPPTHKPKPEHSATALDQGKFHRGYETEEND</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N4T1</accession>
    <name>A0A1C7N4T1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">ATP synthase alpha subunit C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_08285</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000623">
        <property type="protein sequence ID" value="OBZ83666.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N4T1"/>
    <dbReference type="STRING" id="101091.A0A1C7N4T1"/>
    <dbReference type="InParanoid" id="A0A1C7N4T1"/>
    <dbReference type="OrthoDB" id="9805536at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015986">
        <property type="term" value="P:proton motive force-driven ATP synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.150.20">
        <property type="entry name" value="ATP synthase alpha/beta chain, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000793">
        <property type="entry name" value="ATP_synth_asu_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038376">
        <property type="entry name" value="ATP_synth_asu_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00306">
        <property type="entry name" value="ATP-synt_ab_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47917">
        <property type="entry name" value="C-terminal domain of alpha and beta subunits of F1 ATP synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ATP synthase alpha subunit C-terminal" evidence="1">
        <location>
            <begin position="2"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ83666.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="72" mass="8135" checksum="211DAFF7621E8BCC" modified="2016-11-30" version="1" fragment="single">IQAQVPIIFAGVNGYLDKIPVNKVVEWEKDFISHVATQHADVLEEIRTKGVLSKELEAKLRDVCDNHAKGFY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N4T7</accession>
    <name>A0A1C7N4T7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_07838</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000554">
        <property type="protein sequence ID" value="OBZ84110.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N4T7"/>
    <dbReference type="InParanoid" id="A0A1C7N4T7"/>
    <dbReference type="OrthoDB" id="2387796at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ84110.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="633" mass="73971" checksum="AFB833AF1FE55A2F" modified="2016-11-30" version="1">MHVPIEVIKEVGKYLTVADKGECMRVCYGWYKPFLELQYTKVYIRTRHQFKLFYRAIQSSSEINNPLGNHVESLKLGNRVGLTRDEFESLPVLFQHLQLLEFDPRLWRYMRPSEQLMRFNHMRHLPTFNKLNLFQSLFDISNRSWTDQLTYLSIDGTILEYLLNNQLILSIWSRLSKLEELVLQGNNYTPLNVKVIMALGAQLPRLKNLTLSCVTLPLEESDLCSTTTIPLFSSAVSLRLDDVHIKTWRVITFLSLAFYHIQSLDLDMTFDWFYSDNVTIELYEQTMDACMGLAQMCIFLKKIKFRRVNTSVFPFPYDTFFQEIEDIHLDKVLIEMTQSAWWSTIDPAASFRAVTTQTGLLSKCSLKWSWTGKKTEAGLLKNLSCCPNLTELELDCDIPLKHGFRVDALLDHCPQLQSLSLANAMVTTHRAIEKATEKRYRLKALTLKQSVLGDHLMDYLAQSCLGLDQLTIAHCVQEKPRRSLFFVIRMPEHQFKFIKLDSIYLNPGGSEQRSQVDMAILSFYESTRYTHQIERRKRAKRNEEDGPTPEMWRFYHVHSSKQTVRKQLKRLSTDEAARIANFQMNDKKWKLVKNASKRKQYTERNLWEKDIQFGAVLLLAKSVDTLEFNELKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N4W1</accession>
    <name>A0A1C7N4W1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_08282</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000623">
        <property type="protein sequence ID" value="OBZ83669.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N4W1"/>
    <dbReference type="STRING" id="101091.A0A1C7N4W1"/>
    <dbReference type="InParanoid" id="A0A1C7N4W1"/>
    <dbReference type="OrthoDB" id="2230296at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="276"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="317"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="118"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="182"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="126"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="183"/>
            <end position="193"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ83669.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="350" mass="40369" checksum="75748B3BC15D66B2" modified="2016-11-30" version="1">MDQQSTSQPKRLIHSRTNSYNNIQYHESTSSRNSMNLIEGTTLHFPQGNNKKPNSASMVDARLQRQRWDAFFEPQYSFNAFNYEDKQSATQDDELHKKKMDKLIDEGNIMLEVFKTPRSSSRHSYENSPSHFSASSTPTAGIMTPTLPCLNIDKTKSDKQIRRLEDEAMLMSRLELLKKIRMQSDSQRQCGQTDTDDIPEEPRTNTTQTTPIAANWKQLTEKAKRLHKEAQADAKSVVTSRSSTSSLELDEKQADIANEKESSKGCLPYRQSFLCFIFGFLFPPLWLVGAFYVSPYAKRQPSADRRMDRIWRRRSRIALCIFSVVLLILLVVFFVVRPDLVGWRRSKQPI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N5A0</accession>
    <name>A0A1C7N5A0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Aldehyde reductase 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">ARI_0</name>
        <name evidence="6" type="ORF">A0J61_07666</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000531">
        <property type="protein sequence ID" value="OBZ84280.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N5A0"/>
    <dbReference type="STRING" id="101091.A0A1C7N5A0"/>
    <dbReference type="InParanoid" id="A0A1C7N5A0"/>
    <dbReference type="OrthoDB" id="416253at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016616">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd19071">
        <property type="entry name" value="AKR_AKR1-5-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.100:FF:000002">
        <property type="entry name" value="2,5-diketo-D-gluconic acid reductase A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="entry name" value="NADP-dependent oxidoreductase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020471">
        <property type="entry name" value="AKR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018170">
        <property type="entry name" value="Aldo/ket_reductase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036812">
        <property type="entry name" value="NAD(P)_OxRdtase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023210">
        <property type="entry name" value="NADP_OxRdtase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11732">
        <property type="entry name" value="ALDO/KETO REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00248">
        <property type="entry name" value="Aldo_ket_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000097">
        <property type="entry name" value="AKR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00069">
        <property type="entry name" value="ALDKETRDTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51430">
        <property type="entry name" value="NAD(P)-linked oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00798">
        <property type="entry name" value="ALDOKETO_REDUCTASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00062">
        <property type="entry name" value="ALDOKETO_REDUCTASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NADP-dependent oxidoreductase" evidence="5">
        <location>
            <begin position="19"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="2">
        <location>
            <position position="53"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="111"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="site" description="Lowers pKa of active site Tyr" evidence="4">
        <location>
            <position position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR000097-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR000097-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR000097-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OBZ84280.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="306" mass="34793" checksum="CDBAF8CFC40A8735" modified="2016-11-30" version="1">MPNVPTVKLNSGYDFPLIGYGTFGGHDAVNQVYEASKTALELGYRHFDTAYSYGTEQVLGKAIKESKVPREEVFITTKLWNNFHEPQHVAPVFKRSLENLDVDYIDLYLMHWPFAWPFHGYELEDQKESATVLDVPIIDTWREMEKLVKSGKARSIGVSNFTIPMLEDLLRQCEIPPAVNQIEIHPKLVQEDMLAYCKSKNIVLTAYSPLGNPGYRNNVLKTVEEPLILDLAKKYNKSPQQILLNWGVNRGYAVIPKSVTPSRIEANLEYFKMDQEDVDAITALGHGDIVRTCDPKKIWGEGNSIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N5B1</accession>
    <name>A0A1C7N5B1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">BHLH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_07749</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000542">
        <property type="protein sequence ID" value="OBZ84197.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N5B1"/>
    <dbReference type="STRING" id="101091.A0A1C7N5B1"/>
    <dbReference type="InParanoid" id="A0A1C7N5B1"/>
    <dbReference type="OrthoDB" id="5344169at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.280.10">
        <property type="entry name" value="Helix-loop-helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011598">
        <property type="entry name" value="bHLH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036638">
        <property type="entry name" value="HLH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00010">
        <property type="entry name" value="HLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00353">
        <property type="entry name" value="HLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47459">
        <property type="entry name" value="HLH, helix-loop-helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50888">
        <property type="entry name" value="BHLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BHLH" evidence="2">
        <location>
            <begin position="370"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="227"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="278"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="401"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="459"/>
            <end position="514"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="47"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="59"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="236"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="278"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="291"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="409"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="474"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="495"/>
            <end position="514"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50888"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ84197.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="514" mass="57792" checksum="8B4E41B0E70CE6E1" modified="2016-11-30" version="1">MDFSSFELQPNTSPFKQDFTPHPHDSESAQPSDDAEFFHFMNSHYETPSTTASSSSFTMPQLSPEDNTSHLSGHPEFNMSPLQIASQPITNTLYNTPSHPSILEDEEEFFTPLVSPAIAPTYNTSYASLNNSFSPLTSPALHPTSYTLSDQTTLQQKLAFIERQQQQLRTMHHQLHSTKASPVLASTKKTLQPKIASNSPHISPRPFTTDTTDIIAPATPSLLMKLGSGLNSSHPATSASTPVPNTTATTNNSSPSVVDHMPTLPAAILPPEINKIKKKEPKRRRISSHCSPGLSPSLDSPLVRPIQSPRALKPFISPSLKPDGKRLSMIEEETARALLTSKSNYENLKEGKAKSLGIDFSTTIQSGIENRRSAHKAAEQKRRDTLKQSFDSLRAEIMDALISEENDSEDRQTKEKDVKQMSKVVLLQHSYEYILRLKNENKRKEEKQNKMRTELMALRRQLGLPEVTEEEKEAEERERKEELDRREASRKRLQKMADHQENNDLFDMKNKLDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N6B6</accession>
    <name>A0A1C7N6B6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Vezatin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">A0J61_07389</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell junction</location>
            <location evidence="2">Adherens junction</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="3">Cell membrane</location>
            <topology evidence="3">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the vezatin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000496">
        <property type="protein sequence ID" value="OBZ84561.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N6B6"/>
    <dbReference type="STRING" id="101091.A0A1C7N6B6"/>
    <dbReference type="InParanoid" id="A0A1C7N6B6"/>
    <dbReference type="OrthoDB" id="21151at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017022">
        <property type="term" value="F:myosin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098609">
        <property type="term" value="P:cell-cell adhesion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026859">
        <property type="entry name" value="Myosin-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026858">
        <property type="entry name" value="Vezatin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15989">
        <property type="entry name" value="VEZATIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15989:SF5">
        <property type="entry name" value="VEZATIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12632">
        <property type="entry name" value="Vezatin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0965">Cell junction</keyword>
    <keyword evidence="6" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="10 13" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="11" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-0539">Nucleus</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="Myosin-binding" evidence="15">
        <location>
            <begin position="123"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="481"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="13">
        <location>
            <begin position="551"/>
            <end position="578"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004536"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00018125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022949"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF12632"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="OBZ84561.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="600" mass="68554" checksum="96801ADA787F320C" modified="2016-11-30" version="1">MTEFVVYEDSPLAEYLESIDQAETTVKLEPPPLSLRTNSSKQPDRRRLDISKIWRNSLFHDTFSISLSRAEESAFEEKFKYLIVTSPLLSEVLSVHKNKQLSELPFQSPRTTKLGATTNLLATLAILFGAEKYLMRSKLPTISLLFSSSASLFLLVKHKRRACIRQLYQTALSRLQIFTDHSDTFDTKIHRVLITIQEIELVSRGFRLSSPLPPISRIDQNGKQRKCTQLRNALASILRRAFIVYEEGIIDLMDAVNKKNLATLYDMYNVHSIASLSAVDFSTDSEEPSLDQLKKLAQVMHSKRRECMVQLLALDAITKEHESVQYDYRSAWKSINDVLRKLVDETDCFAKELGEILDAEFYKPINNFDKRSLSSKIEDARLKKFVHRLSSLEQQLRTMEAKIYLCSEDVRQLNSGTKKTASLSRNQLTMSLAPSDQISTKERLLNEYSSVQKGLEEMVLEWQSGKEMLEAFLNPPTLEQQNTLTEEPEPIEPSTPIEESEGKGMLLDSEDVADILNLPVASKASVFEAIAGVVEKNGKERSVKTRQERIEEMKQRRIKESEEKASRLDSQIMVHELKNVLDKRAIELDLKDSDANDHKM</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N6M5</accession>
    <name>A0A1C7N6M5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_07166</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000469">
        <property type="protein sequence ID" value="OBZ84783.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N6M5"/>
    <dbReference type="STRING" id="101091.A0A1C7N6M5"/>
    <dbReference type="InParanoid" id="A0A1C7N6M5"/>
    <dbReference type="OrthoDB" id="5556956at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000462">
        <property type="term" value="P:maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053030">
        <property type="entry name" value="Ribosomal_biogenesis_FAF1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28096">
        <property type="entry name" value="PROTEIN FAF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28096:SF1">
        <property type="entry name" value="PROTEIN FAF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="16"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="88"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="132"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="201"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="31"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="91"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="132"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="236"/>
            <end position="250"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ84783.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="250" mass="28280" checksum="1DEB95AF0B01C36C" modified="2016-11-30" version="1">MSSLADLISSVKANTSKNAHIARSLKRKAGPSKEELKQQRKKQLIEKKKTAVAQSVVVFDNSVLEKKQTFEDKASKKQFLSSKITSIESHTTIEKKEKPTAKDLEEEAENQRHDQELKQLLATSHLLEELEREEMTSKERRQNTMKKLETLGVKASSNDKMPLAYKLSLDESIKKKGLAKLQEAKDLGIYDKSLKHLYVKTKPKKRDRDPGITNGLGRMKGATLTIKKSDIDRINRQGKKKPSSGGKKKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N6N0</accession>
    <name>A0A1C7N6N0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Endosomal/vacuolar adapter protein YPT35</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">PX domain-containing protein YPT35</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="primary">YPT35</name>
        <name evidence="13" type="ORF">A0J61_07654</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Recruits the lipid transfer protein VPS13 to endosomal and vacuolar membranes.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Endosome</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Vacuole membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the YPT35 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000529">
        <property type="protein sequence ID" value="OBZ84296.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N6N0"/>
    <dbReference type="STRING" id="101091.A0A1C7N6N0"/>
    <dbReference type="InParanoid" id="A0A1C7N6N0"/>
    <dbReference type="OrthoDB" id="10254720at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010008">
        <property type="term" value="C:endosome membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005774">
        <property type="term" value="C:vacuolar membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032266">
        <property type="term" value="F:phosphatidylinositol-3-phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07280">
        <property type="entry name" value="PX_YPT35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1520.10">
        <property type="entry name" value="Phox-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001683">
        <property type="entry name" value="PX_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036871">
        <property type="entry name" value="PX_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037917">
        <property type="entry name" value="Ypt35_PX"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10555:SF170">
        <property type="entry name" value="FI18122P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10555">
        <property type="entry name" value="SORTING NEXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00787">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00312">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64268">
        <property type="entry name" value="PX domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50195">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0967">Endosome</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0926">Vacuole</keyword>
    <feature type="domain" description="PX" evidence="12">
        <location>
            <begin position="255"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="163"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="10">
        <location>
            <begin position="35"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="172"/>
            <end position="184"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004148"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007426"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022554"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022753"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00033728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00033774"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00033785"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="OBZ84296.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="365" mass="41748" checksum="B7A26C20E11A1125" modified="2016-11-30" version="1">MTDYQQTINNVLEHAQSEYAHMEVMIKQKKTTPLLQQTAKDLREGIKKLVQLQDNLDDIGSVVESNTEWIKRAETVLSEVKKQLQIAKNISVTHINTNMKPMTSQSSPLKLSNAQRHKINYDFDIQEEEEEEEEDRFEDASEELNISKRGSKLLAKLAESSPIERTEAAETTFPTSISNQQEPSRSVFGRRSVLVNNLIDDQHTEQNEKKPKASLFPLLRGLRTSQSTPVNNSAPVHINFYQNDNVQKGDKDFIFATDAIVDHPLRIGAGYGSYICYNCTVLSDKGTPITVRKRYSDFVDLREDLVKQYPMLKRSIPKLPPKKVVGKFTPSFVEQRRKDLEYFFKYVVLHPTLGASPIIKHWIAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N6R7</accession>
    <name>A0A1C7N6R7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 8">Pectinesterase</fullName>
            <ecNumber evidence="3 8">3.1.1.11</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">PME58</name>
        <name evidence="10" type="ORF">A0J61_07141</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Involved in maceration and soft-rotting of plant tissue.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6 8">
            <text>[(1-&gt;4)-alpha-D-galacturonosyl methyl ester](n) + n H2O = [(1-&gt;4)-alpha-D-galacturonosyl](n) + n methanol + n H(+)</text>
            <dbReference type="Rhea" id="RHEA:22380"/>
            <dbReference type="Rhea" id="RHEA-COMP:14570"/>
            <dbReference type="Rhea" id="RHEA-COMP:14573"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17790"/>
            <dbReference type="ChEBI" id="CHEBI:140522"/>
            <dbReference type="ChEBI" id="CHEBI:140523"/>
            <dbReference type="EC" id="3.1.1.11"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 8">Glycan metabolism; pectin degradation; 2-dehydro-3-deoxy-D-gluconate from pectin: step 1/5.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the pectinesterase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.11" evidence="3 8"/>
    <dbReference type="EMBL" id="LUGH01000466">
        <property type="protein sequence ID" value="OBZ84810.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N6R7"/>
    <dbReference type="STRING" id="101091.A0A1C7N6R7"/>
    <dbReference type="InParanoid" id="A0A1C7N6R7"/>
    <dbReference type="OrthoDB" id="1546079at2759"/>
    <dbReference type="UniPathway" id="UPA00545">
        <property type="reaction ID" value="UER00823"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030599">
        <property type="term" value="F:pectinesterase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042545">
        <property type="term" value="P:cell wall modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045490">
        <property type="term" value="P:pectin catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.20.10">
        <property type="entry name" value="Single-stranded right-handed beta-helix, Pectin lyase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012334">
        <property type="entry name" value="Pectin_lyas_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011050">
        <property type="entry name" value="Pectin_lyase_fold/virulence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033131">
        <property type="entry name" value="Pectinesterase_Asp_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000070">
        <property type="entry name" value="Pectinesterase_cat"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31321">
        <property type="entry name" value="ACYL-COA THIOESTER HYDROLASE YBHC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31321:SF58">
        <property type="entry name" value="METHYLESTERASE, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01095">
        <property type="entry name" value="Pectinesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51126">
        <property type="entry name" value="Pectin lyase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00503">
        <property type="entry name" value="PECTINESTERASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8" id="KW-0063">Aspartyl esterase</keyword>
    <keyword evidence="8" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="4 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0964">Secreted</keyword>
    <feature type="domain" description="Pectinesterase catalytic" evidence="9">
        <location>
            <begin position="10"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="active site" evidence="7">
        <location>
            <position position="155"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008891"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00047928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000589"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01095"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OBZ84810.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="326" mass="35671" checksum="9462CC496907D7F1" modified="2016-11-30" version="1">MSEAASVKVCASCDYQTISDALHALPNDNQSYTVSIAAGVYNERIWVNRSNVNLEAAGSGKVYIQYSIAHNTQDPSSHAWEKAVVTVNGNNVSFRNLVLSNTFKQTRNIATVALNVQGQKVSFYKTKIYGFQDTLLISAAGTAYFKDCYVEGSVDFIFGYGVGYFQGCVIGSNAVGYVTAQNRASESATGGFYFNQCHMKATIPSGPIASNADNTLSFTSNTQFANSTYLGRPWSQYARVVYMNSYFENHIKPAGWSIWKATDPRINHVLFGEYKNNGPIGSFGSLRAPFASLLNSTDIAHYKPFPAIDCALKEKGCIEKAFGLHK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N7I5</accession>
    <name>A0A1C7N7I5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_07364</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000492">
        <property type="protein sequence ID" value="OBZ84586.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N7I5"/>
    <dbReference type="InParanoid" id="A0A1C7N7I5"/>
    <dbReference type="OrthoDB" id="2246002at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="40"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="85"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="40"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ84586.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="109" mass="12932" checksum="137E720306971F21" modified="2016-11-30" version="1">MGLIEKLKNSYDYRKVDKYTKRRVSQSQFQSQDRRYYETAYRDGDYLDPEDMRTGRYDPNAPTSTRLAYKQSRWSFTDLLSKNNTQKKPMTITSSQIRTSESYTLSGRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N7N7</accession>
    <name>A0A1C7N7N7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">GTPase-activating protein GYP5</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">GYP5_4</name>
        <name evidence="5" type="ORF">A0J61_07310</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000486">
        <property type="protein sequence ID" value="OBZ84639.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N7N7"/>
    <dbReference type="STRING" id="101091.A0A1C7N7N7"/>
    <dbReference type="InParanoid" id="A0A1C7N7N7"/>
    <dbReference type="OrthoDB" id="295078at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031267">
        <property type="term" value="F:small GTPase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.472.80:FF:000027">
        <property type="entry name" value="GTPase activating protein (Evi5)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.270:FF:000001">
        <property type="entry name" value="TBC1 domain family member 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.270">
        <property type="entry name" value="putative rabgap domain of human tbc1 domain family member 14 like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.80">
        <property type="entry name" value="Ypt/Rab-GAP domain of gyp1p, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000195">
        <property type="entry name" value="Rab-GAP-TBC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035969">
        <property type="entry name" value="Rab-GAP_TBC_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050302">
        <property type="entry name" value="Rab_GAP_TBC_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47219:SF9">
        <property type="entry name" value="GTPASE ACTIVATING PROTEIN AND CENTROSOME-ASSOCIATED, ISOFORM B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47219">
        <property type="entry name" value="RAB GTPASE-ACTIVATING PROTEIN 1-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23436">
        <property type="entry name" value="RabGap-TBC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00164">
        <property type="entry name" value="TBC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47923">
        <property type="entry name" value="Ypt/Rab-GAP domain of gyp1p"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50086">
        <property type="entry name" value="TBC_RABGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0343">GTPase activation</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rab-GAP TBC" evidence="4">
        <location>
            <begin position="169"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="39"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="437"/>
            <end position="570"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022468"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OBZ84639.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="572" mass="66462" checksum="1391FE341282064A" modified="2016-11-30" version="1">MSSSDNKLNDYDLSVLDEALLYPEKTEYVDHFGFRVQVKSEHDTDSSESEFEDAQSLSSDLKTPKPDETEEEEDDTDWRSSTTADKISVVSMPTSSTTSYYDMLLSKFTRNDTPSKQLQIETYQNLEKLKEESTEDKEIDWEFWTSVVSDFERINRTDHAKLRQQLCVGIPTSLRGLLWRIFSKSEMNSELIENEYRLLLEKTSSHEKLIQRDLSRTFPTLDYFKDKDGEGQAMLFNVIKAYSLFDSQVGYCQGLHFVVGCLLLHMPDEAAFCVLLRLMSQYGLRGHFTPQMETLHERMFQFNQLLALQLPQVHRHLHAQGVLPSMYASQWFMTLFAYRCPLDLVFRVFDLVFVEGPQIMLNFALALMKKNQSTILSLEFESLLDFFSGQIFEVYKDCAYDFVQDAYSFTVSPKQLSKFSKQYRQEAAKEAKLQSMQDAIKKENIVLQDQLKKLRQAYKTLASEHRDVAQQVIDSKLTMASLSSENQQLKHELSAIKQDMGTLSSALHQERQIQFDLLAQKNAQLVDANALLEDRLQEMEVILIEMKLKYAESENDYEQMKQKLHEAQKLMR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N7X3</accession>
    <name>A0A1C7N7X3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DNA polymerase delta subunit 3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">Pold3</name>
        <name evidence="6" type="ORF">A0J61_06779</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000425">
        <property type="protein sequence ID" value="OBZ85171.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N7X3"/>
    <dbReference type="FunCoup" id="A0A1C7N7X3">
        <property type="interactions" value="88"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N7X3"/>
    <dbReference type="InParanoid" id="A0A1C7N7X3"/>
    <dbReference type="OrthoDB" id="514823at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043625">
        <property type="term" value="C:delta DNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003887">
        <property type="term" value="F:DNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006271">
        <property type="term" value="P:DNA strand elongation involved in DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1904161">
        <property type="term" value="P:DNA synthesis involved in UV-damage excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006297">
        <property type="term" value="P:nucleotide-excision repair, DNA gap filling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.1030.20:FF:000002">
        <property type="entry name" value="DNA polymerase delta subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1030.20">
        <property type="entry name" value="DNA polymerase delta, p66 (Cdc27) subunit, wHTH domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019038">
        <property type="entry name" value="POLD3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041913">
        <property type="entry name" value="POLD3_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17598">
        <property type="entry name" value="DNA POLYMERASE DELTA SUBUNIT 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17598:SF13">
        <property type="entry name" value="DNA POLYMERASE DELTA SUBUNIT 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09507">
        <property type="entry name" value="CDC27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0235">DNA replication</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="128"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="176"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="230"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="241"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="268"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="319"/>
            <end position="329"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00017589"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OBZ85171.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="343" mass="38867" checksum="110BB9BBCDD6211E" modified="2016-11-30" version="1">MTDYQEFLTVTVIQERKPVTYKSLARSLGIHVNTAKQALYEFSKSTPDVNTVYCLTGIDYVNSHYTIQLVKESELEDKKKTFRTLTGVHVYSVSSFGLKDMTLLLAAYKDMPKLSLEDRVRYGMLRHTQVSQHKKAKPGPSMSVLPKVKTEITPKSAPLVEPKSTKRKDPFLSNLSAQKKQAVAKPAEKKPKAVKKSQQQQKDDERRMAKTTLKASDIFSDDEDFLSEPQRQKEPTKETPEPEEDVDMDEPEEKPEKKEVLPTLPPGKVRRQVLKKKTTRNARGHLVTEEVLEWEIVDAPKTTEKPTPTSSNPVEAKSNKKKPVAKSNKKPAQSKLSSFFKKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N893</accession>
    <name>A0A1C7N893_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 10">Transcription elongation factor Spt6</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="primary">spt6</name>
        <name evidence="15" type="ORF">A0J61_06626</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Histone H3-H4 chaperone that plays a role in maintenance of chromatin structure during RNA polymerase II transcription elongation thereby repressing transcription initiation from cryptic promoters. Mediates the reassembly of nucleosomes onto the promoters of at least a selected set of genes during repression; the nucleosome reassembly is essential for transcriptional repression. Essential for viability.</text>
    </comment>
    <comment type="function">
        <text evidence="10">Plays a role in maintenance of chromatin structure during RNA polymerase II transcription elongation thereby repressing transcription initiation from cryptic promoters. Mediates the reassembly of nucleosomes onto the promoters of at least a selected set of genes during repression; the nucleosome reassembly is essential for transcriptional repression.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Chromosome</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1 10">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the SPT6 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000409">
        <property type="protein sequence ID" value="OBZ85323.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="FunCoup" id="A0A1C7N893">
        <property type="interactions" value="950"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N893"/>
    <dbReference type="InParanoid" id="A0A1C7N893"/>
    <dbReference type="OrthoDB" id="995477at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005721">
        <property type="term" value="C:pericentric heterochromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008023">
        <property type="term" value="C:transcription elongation factor complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042393">
        <property type="term" value="F:histone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031491">
        <property type="term" value="F:nucleosome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034728">
        <property type="term" value="P:nucleosome organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140673">
        <property type="term" value="P:transcription elongation-coupled chromatin remodeling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd09928">
        <property type="entry name" value="SH2_Cterm_SPT6_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd09918">
        <property type="entry name" value="SH2_Nterm_SPT6_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.2740:FF:000002">
        <property type="entry name" value="Transcription elongation factor Spt6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.505.10:FF:000056">
        <property type="entry name" value="Transcription elongation factor Spt6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.650">
        <property type="entry name" value="RuvA domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.505.10">
        <property type="entry name" value="SH2 domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.2740">
        <property type="entry name" value="Spt6, Death-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.850">
        <property type="entry name" value="Spt6, helix-hairpin-helix domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3500.10">
        <property type="entry name" value="Tex N-terminal region-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.140">
        <property type="entry name" value="YqgF/RNase H-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010994">
        <property type="entry name" value="RuvA_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003029">
        <property type="entry name" value="S1_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000980">
        <property type="entry name" value="SH2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036860">
        <property type="entry name" value="SH2_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049540">
        <property type="entry name" value="Spt6-like_S1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028083">
        <property type="entry name" value="Spt6_acidic_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042066">
        <property type="entry name" value="Spt6_death-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032706">
        <property type="entry name" value="Spt6_HHH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028088">
        <property type="entry name" value="Spt6_HTH_DNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035420">
        <property type="entry name" value="Spt6_SH2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035018">
        <property type="entry name" value="Spt6_SH2_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035019">
        <property type="entry name" value="Spt6_SH2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028231">
        <property type="entry name" value="Spt6_YqgF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055179">
        <property type="entry name" value="Tex-like_central_region"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023323">
        <property type="entry name" value="Tex-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023319">
        <property type="entry name" value="Tex-like_HTH_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017072">
        <property type="entry name" value="TF_Spt6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037027">
        <property type="entry name" value="YqgF/RNaseH-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10145">
        <property type="entry name" value="TRANSCRIPTION ELONGATION FACTOR SPT6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10145:SF6">
        <property type="entry name" value="TRANSCRIPTION ELONGATION FACTOR SPT6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14635">
        <property type="entry name" value="HHH_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14641">
        <property type="entry name" value="HTH_44"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14633">
        <property type="entry name" value="SH2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14632">
        <property type="entry name" value="SPT6_acidic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21710">
        <property type="entry name" value="Spt6_S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22706">
        <property type="entry name" value="Tex_central_region"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14639">
        <property type="entry name" value="YqgF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036947">
        <property type="entry name" value="Spt6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00316">
        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47781">
        <property type="entry name" value="RuvA domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55550">
        <property type="entry name" value="SH2 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF158832">
        <property type="entry name" value="Tex N-terminal region-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50126">
        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50001">
        <property type="entry name" value="SH2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0158">Chromosome</keyword>
    <keyword evidence="15" id="KW-0251">Elongation factor</keyword>
    <keyword evidence="8 10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 11" id="KW-0727">SH2 domain</keyword>
    <keyword evidence="7 10" id="KW-0804">Transcription</keyword>
    <feature type="domain" description="S1 motif" evidence="14">
        <location>
            <begin position="1087"/>
            <end position="1156"/>
        </location>
    </feature>
    <feature type="domain" description="SH2" evidence="13">
        <location>
            <begin position="1206"/>
            <end position="1304"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="124"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1158"/>
            <end position="1199"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="12">
        <location>
            <begin position="9"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="12">
        <location>
            <begin position="46"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="135"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="12">
        <location>
            <begin position="152"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="173"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="1167"/>
            <end position="1190"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009253"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00020248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022999"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00093389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRNR" id="PIRNR036947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="OBZ85323.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="1401" mass="162560" checksum="DE03AB6D26085C5F" modified="2016-11-30" version="1">MRGSMSRSDDEDSNLYGDQDEENSLIQNSDEEGEDIGYSRKGNMINDDDDDDDDEEEDEEEEDDEEEARKIAEGFIVDDEESDASEPVAVRRKKRKKVEEYDDDLDEEDLELLEENTGIKLNRTTGPKLKRLKRGREEQSYDKSKSAGNIFSEEEEEDDEEQATRTSTRRHHHEDEYAQDYDRMGGYRRDAYDDMGDFIADEDEDDLNEVMDERNQARYDEDRGRRGKASKDMMHILPAGISEDVLVDMYDIFGDGADYEWALYEEEDADQAREREPQLADIFEPSELAERMMTEEDEEIRLRDVPERLQMRYEGLNKTFEPATNDQVQEEGAWIARVMARHRGEEHPTDQFMSAVAYVISFFTREFLEVPHIKDHRRDYFTDVDPSTGHSREILTEKDLWEIYDLDFKYHSFVDRRTALREFIAKCQIEDEYMETMLDRVEKVEEIADLTDYINLKYADKINAMQQQARGNKRPTNKSLYELSQNSRLHAFLPQFGISAREFGTNYIETYQRYQPEDQTIDPIVQAEDYTDHNFPDTMKVLKAARSVLAQEMAFDPQVRKAIRKDWELYATVTVRPTEKGYNVIDELHPMKPYKYLTEKPVTEFKNGQFLHLLKGETDGLLSIHIGITDYPAWFNRIAEFYISDGYSDTVQQWNDQRKEIIEQSLKEHLIPLMSKYVREKLRVEAEEYICQHAYNSLYNKINVGAFRGPESHFKSPLPRVVTVSSGSGGPKDPIVAVFVNQRGKVLDHFEVPNLKDERHWKEMADYIKSKKANVLGVAGYNAETRRVIKHMQSMLVEINQSHEHNNLPKMDMVVVDDETARLYKASKRAQDEFGDYSETARYCVSLARRLQSPVMEYAGLGRDLLAIRHHELQSLVPEDTLLFYLERALISVINDLGFDINAAIQSPYLANALQFVCGFGPRKSQSILKKIEASGELESRAALVLRKLTPANTFMNCASYLRIRDIDGADILDDTRIHPQDYELARKMAADALEIDEDEMDDYDSKVAVVTRVIKEYPDKLNDLILDDYAVVLRKQYNAPKRQILEHIKLELQGPYHDRRHRYARPTTEEAFVMVTGETRSTLSEGFIIPAMVVGVRGKIANCVLDSGLEGMIYIDNASDDRIMNIGDVLQVGQTINCKVLRIDRDKFMVDLSCKSSDTKPGSDYTLRKQPEDPYYDHVEETKEREQRRASRRKQARSTRVIKHPLFRPFNHMEAEEYLSSRQRGDLVIRPSSHGPDHIAITWKVDEDVYQHVDVVEVKNKHDMHAPARLKIGDQTFEDLDELIVTYIEAVARKVEELMAHPKYRPGGTNALNEHLTALTQANPKMSAYGFCQSEKPGYFNLGFKLSIRGPPMRWVVRVLPDGYRLRDTSYPQVDDLINGFKRIQHAEAQRHKKRSMNRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N8G7</accession>
    <name>A0A1C7N8G7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="15">ATP-dependent helicase rhp16</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="15" type="primary">rhp16</name>
        <name evidence="15" type="ORF">A0J61_08307</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SNF2/RAD54 helicase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000627">
        <property type="protein sequence ID" value="OBZ83644.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N8G7"/>
    <dbReference type="FunCoup" id="A0A1C7N8G7">
        <property type="interactions" value="251"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N8G7"/>
    <dbReference type="InParanoid" id="A0A1C7N8G7"/>
    <dbReference type="OrthoDB" id="448448at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031463">
        <property type="term" value="C:Cul3-RING ubiquitin ligase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000113">
        <property type="term" value="C:nucleotide-excision repair factor 4 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008094">
        <property type="term" value="F:ATP-dependent activity, acting on DNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004842">
        <property type="term" value="F:ubiquitin-protein transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070911">
        <property type="term" value="P:global genome nucleotide-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008104">
        <property type="term" value="P:intracellular protein localization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000715">
        <property type="term" value="P:nucleotide-excision repair, DNA damage recognition"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009411">
        <property type="term" value="P:response to UV"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006511">
        <property type="term" value="P:ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd18008">
        <property type="entry name" value="DEXDc_SHPRH-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd23142">
        <property type="entry name" value="RING-HC_CHR27-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18793">
        <property type="entry name" value="SF2_C_SNF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10810">
        <property type="entry name" value="Tandem AAA-ATPase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002464">
        <property type="entry name" value="DNA/RNA_helicase_DEAH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038718">
        <property type="entry name" value="SNF2-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049730">
        <property type="entry name" value="SNF2/RAD54-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000330">
        <property type="entry name" value="SNF2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050628">
        <property type="entry name" value="SNF2_RAD54_helicase_TF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018957">
        <property type="entry name" value="Znf_C3HC4_RING-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45626:SF12">
        <property type="entry name" value="DNA REPAIR PROTEIN RAD16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45626">
        <property type="entry name" value="TRANSCRIPTION TERMINATION FACTOR 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00176">
        <property type="entry name" value="SNF2-rel_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00097">
        <property type="entry name" value="zf-C3HC4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00690">
        <property type="entry name" value="DEAH_ATP_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7 15" id="KW-0347">Helicase</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0862">Zinc</keyword>
    <keyword evidence="5 10" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="13">
        <location>
            <begin position="244"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="domain" description="RING-type" evidence="12">
        <location>
            <begin position="579"/>
            <end position="623"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="14">
        <location>
            <begin position="678"/>
            <end position="820"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="21"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="11">
        <location>
            <begin position="60"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="87"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="126"/>
            <end position="153"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007025"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="OBZ83644.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="833" mass="95033" checksum="81A6966E21D49642" modified="2016-11-30" version="1">MVSLRRTSQRLNKKPKLDTGSSSSTVKRSPVSKMEVKDEDSSSSDSSDDFQAPVAVRALRSSRAKGKQPVRARQPIQLTDNSDDESVQSNSLFSRQSPKSSDTSLETSDDQKEEASVAPSGLKDEAEIDSDSQQGSDDEFAGEDDEEEEEASEDSSSNSSEEEEQAPVRFLPNRRRNPRIPRQQVRSYQRTQLKILSHHKELKNIWEDLESIEPEAVVPVEQPAELTLQLLPFQKYGVGWMRRQENMDTFKGGVLADEMGMGKTIQTIALLLTDRKKPNLVIAPTVAILQWKAEIERHTNNALSVYIFHGKRTSNADELKKYDVVLSTYSIMESSFRRQEQGVHNKATRSIKKEKSALHKVQWHRVILDEAHNIKDRASNTARSVFNINANYKWSLTGTPLQNRVGELYSLIRFMQADPFAYYYCKQCPCKEISWKFSNKRTCDSCGHTPMNHTCWWNNEVLKPIQYHGYLDEGREAMKKLGILLDKIMLRRTKIQCADDLGLPPRTVIVRRDLFTEEEEDVYTSLYSDVQRTFTTYVEEGTVLNNYANIFELLMKMRQCADHPDLVTKKSSDNKQLVCMLCNDPPEDAIAAACKHVFCRECCVQYYDSFDDHAGEKPRCPSCFAEFSVDLSQPALEVEGSGHGTNANFSKSSIVNRINMNSWRSSTKIEALVEELSNLRQEDKTIKSIVFSQFVNFLDLVYWRLSRAGFECIRLDGTMTPDQRNAAINCFMNKPTVTVFLISLKAGGVALNLTEASRVFICDPWWNPAMDRIHRLGQHRPIRITRLIIENSIESRIIQLQEKKTALVESTVDKNSKALDKLTVEDLRFLFVM</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N8Y5</accession>
    <name>A0A1C7N8Y5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_06902</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000439">
        <property type="protein sequence ID" value="OBZ85046.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N8Y5"/>
    <dbReference type="InParanoid" id="A0A1C7N8Y5"/>
    <dbReference type="OrthoDB" id="2272123at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ85046.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="132" mass="14781" checksum="0EBDE2BECD3949E3" modified="2016-11-30" version="1">MDLNLCLYCEKRLADDSMAFCSLPCQTKEATKSMSTSFGSFHSDNTMQYDVYQISYRRSPSLTYPISIRQRKDSSDFSIARPPPRYLVQSASTSSSSFSSSMSDISTFSCEDKVGTLCSSYHITRTTHNIAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N9G5</accession>
    <name>A0A1C7N9G5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_06179</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000361">
        <property type="protein sequence ID" value="OBZ85772.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N9G5"/>
    <dbReference type="InParanoid" id="A0A1C7N9G5"/>
    <dbReference type="OrthoDB" id="2240906at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008889556" evidence="1">
        <location>
            <begin position="22"/>
            <end position="147"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ85772.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="147" mass="16435" checksum="AF28A4D2D8F2C1A5" modified="2016-11-30" version="1">MKFTIVSYLIALMVTVQVAMADVFSQLQFMKIESPTNNQNVRPGESVVIKYAMQPLVYKQVSNGMAKSLKINFHKRAGNTKQELVQEDVVRKCPVAALESKFKTYKTTWTVPSNTAPGSYALDFVELVQLRRGQMTASETVKLNVVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N9K3</accession>
    <name>A0A1C7N9K3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="13">ATP-dependent bile acid permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">YBT1_4</name>
        <name evidence="13" type="ORF">A0J61_06178</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000361">
        <property type="protein sequence ID" value="OBZ85771.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N9K3"/>
    <dbReference type="InParanoid" id="A0A1C7N9K3"/>
    <dbReference type="OrthoDB" id="6500128at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000329">
        <property type="term" value="C:fungal-type vacuole membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd18596">
        <property type="entry name" value="ABC_6TM_VMR1_D1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18604">
        <property type="entry name" value="ABC_6TM_VMR1_D2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1560.10:FF:000013">
        <property type="entry name" value="ABC transporter C family member 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="entry name" value="ABC transporter type 1, transmembrane domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050173">
        <property type="entry name" value="ABC_transporter_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24223:SF353">
        <property type="entry name" value="ABC TRANSPORTER ATP-BINDING PROTEIN_PERMEASE VMR1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24223">
        <property type="entry name" value="ATP-BINDING CASSETTE SUB-FAMILY C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="ABC transporter transmembrane region"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="102"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="139"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="268"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="313"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="440"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="523"/>
            <end position="545"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1026"/>
            <end position="1051"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1080"/>
            <end position="1100"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1151"/>
            <end position="1172"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1179"/>
            <end position="1195"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1263"/>
            <end position="1284"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1290"/>
            <end position="1310"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="12">
        <location>
            <begin position="270"/>
            <end position="582"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="11">
        <location>
            <begin position="682"/>
            <end position="926"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="12">
        <location>
            <begin position="1042"/>
            <end position="1318"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="11">
        <location>
            <begin position="1355"/>
            <end position="1594"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="365"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="374"/>
            <end position="384"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="OBZ85771.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="1610" mass="183284" checksum="7280EAC50A646917" modified="2016-11-30" version="1">MSCFHFLSAKNTFDSSETPKRPPSITNLKSKISSLAFLFAWRLESVILDRSKKPPTSEPSPPPYQLVDPCLACLPRIYILILVIKSFTTPENPLDSSKFTRYSYHFVIFYSLILVSAFIRVGDYFLTSNNWYISSSIEQSFALIDVVLCTLLWYVIMTSPTELDQAELVDFDDDEDGVLVLFDGRVVRNGRILSLESSASPMSSLTFSWMNSLLKTAYVSRLTSDMLWALPVRQRAKENFRFFAQTKRSIRVTSGSILKRLYIANRKIVWWQFITAIGAVIFHFANPLFLYLLLSHIEQSKHDNQRQMIQEVGLMYCVALFICNVTSTVVASQTLLWGRRWHVAVINMISSETYAHALRLKGRHTKPLQRESSEAEEEEDENDEDYIHQKTSLMSQDTERLAELASYLHSHPYVGVKIFYTCPLEITAGVVFLYQLLGSSFLVGLIVMVVALPSTHYISRRLMIAQVHLSDAKSWRLRLVRELCEGIKTIKFLASERRWEQVIMSARADELVKLIKLYTQNTLLSLIWFATPVFVTTISFAWHTIVQKKSLDASTAFVSIVLFGMLRDPLNVLPQAFMAYNDAKTSLSHITTFLNTEVKQDDPIFHEQQTYCEQVKVGFESAHSIFKWASEMSFGEEHQHRQHQHQHQLGKQYDTFAPSLPHTERPSRSRTVTYGSTASTPLAFSPTETNLNTASFRLVIDQPFLFPTGKLSVISGPSQSGKTSLLAALLGDMAMIAGDKVPLLPSRFLYQQQGLVRDGSLYLHKVAYVSQMPWIEHGTIRENILFFEPWDDTRYRTVLHQCDLLRDLSLFDNGDLTLATEKSVVSLDALKHKISLARAVYSRCKTVIIDDIFMILGKTTSTFIYENCIRGDLMKERTILVAVTYPDMFWARDAHMFVHMAVSLHDEGHIQSFETDPERIVQLIKHRRNEQQQQRKENLKQEKAGFEKIVAIDETRNQNSFMNPVQANEADVVDVLFEYTGGAGSIHNNSSTLFDENIFDDNSLMPDSIEQEDELSSEERHKRRNFAYATYASACGGWRYWIMAILFTLLARLANISESFWLKEDNELSETMSLTPNQYVLIYLGICLVAVVCNFIRTVVQYRGSLRASNHIFLNLLQSVCHAPLQFFDITPISQIMSRFSKDVDTVDSSIGWHINFLLQTIFGVIGVVFAVGIIIPEFLFTGSVAAIAYIYIGLTYVRASRELKRLNDESRPPIFHLYSDTLAGLATIRAYGEEWSMMKKMFSRLDDHMRSFYTLWNTNRWLFIRVELLGALLSFFVGVSIIFNNIDAGLAGIALTLSTSLLEYVYWLMRQSTTVSMHFESVERINDYIMMPQEPPSIVEGSRPPAAWPTNAAIQVKDLVVGLNNSEADTVLRHVSFNVSSGEKVALIGRAGAEKHALVSCLFRFMEPLHGSIKIDGINTAWIGVEDLRSRITFISKEGWLLNGTVRSNLDPFGEYDDYAIWQVLYQVKLANSPTDIHHSVSIQDLDLDLGKEGCYLSVCQRQLLCIARALLQDCTKLVIIEEAHLNPEEKELLQAVIAHEFEESTVLVIPYMLRDVVLYDKVMVFDQGSLIEYDSPIELLNKQHGLLASLYEKAGILDSLTLYTNTPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N9N1</accession>
    <name>A0A1C7N9N1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_07890</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000562">
        <property type="protein sequence ID" value="OBZ84054.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N9N1"/>
    <dbReference type="STRING" id="101091.A0A1C7N9N1"/>
    <dbReference type="InParanoid" id="A0A1C7N9N1"/>
    <dbReference type="OrthoDB" id="1728974at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10492">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10492:SF57">
        <property type="entry name" value="ATP-DEPENDENT DNA HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ84054.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="339" mass="39336" checksum="5E9316446C8EE359" modified="2016-11-30" version="1" fragment="single">NGSIVIDNGWFVPYNPYLSKKFKAHINVKCCQSVDPIKFINKYVYGDSDRTTLKPSNNESEIERHLQGRYFGPTEASARILEYKIHEEDPTVALLALHLPNQQSVYFLEDATPSELEHAFANSRTMPIAYFYHYQNNPTAQKYLYQDFPQYFVWNKKDRVPQSGERFYLRLLLINVAGSKSFEDLQSVDGVQCETFMQVCLRLHLTEDNQKWSHCFNEAVMFSTGSSLRNLFVTALTFVQMIEPALLWEEFCVAICDDLAHKLQTLFPGQLHEKYTLTDDSLFYKGQSEWDYGLFLLDEKLGRLGSSLETCQMLSYKIDWANDLEILANTEDIIKQIDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N9R3</accession>
    <name>A0A1C7N9R3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Putative mitochondrial import receptor subunit tom40</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">tom40</name>
        <name evidence="10" type="ORF">A0J61_06118</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion outer membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the Tom40 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000354">
        <property type="protein sequence ID" value="OBZ85831.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N9R3"/>
    <dbReference type="FunCoup" id="A0A1C7N9R3">
        <property type="interactions" value="276"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N9R3"/>
    <dbReference type="InParanoid" id="A0A1C7N9R3"/>
    <dbReference type="OrthoDB" id="19656at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005742">
        <property type="term" value="C:mitochondrial outer membrane translocase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008320">
        <property type="term" value="F:protein transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030150">
        <property type="term" value="P:protein import into mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045040">
        <property type="term" value="P:protein insertion into mitochondrial outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd07305">
        <property type="entry name" value="Porin3_Tom40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.160.10">
        <property type="entry name" value="Porin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023614">
        <property type="entry name" value="Porin_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027246">
        <property type="entry name" value="Porin_Euk/Tom40"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037930">
        <property type="entry name" value="Tom40"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10802">
        <property type="entry name" value="MITOCHONDRIAL IMPORT RECEPTOR SUBUNIT TOM40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01459">
        <property type="entry name" value="Porin_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6" id="KW-1000">Mitochondrion outer membrane</keyword>
    <keyword evidence="7" id="KW-0653">Protein transport</keyword>
    <keyword evidence="10" id="KW-0675">Receptor</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1134">Transmembrane beta strand</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004374"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010510"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022452"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OBZ85831.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="338" mass="37324" checksum="13CBDCF4B42BABD7" modified="2016-11-30" version="1">MATPEVATTAPAAPRYFSPLSGPFGLNKDQKPSGSPWNPLQWPAWFTYQKSRLNLPSPGKFERLHAEATKDTFTTNYLFDGAQANIVKELSANFHVQHQFSLGSQVMPPMYNFMSGYMTERTMLQGTMDNDTNLNGVLRHAWSPFSVTKVVAQFTHMPGHSMVQLDQEFNGSDYSVNLKAMNPNPLEFTGLYMASYLQSVTQQLAIGSEIVLQRPTPDMEETAMSLVGKYTGKDYIATAQFQGAGAIQASYYQRINEKVDFGVELNLMVQGGRREAVATVGGKFDFRQATFRGQIDTTGKVSAVLEEKMAPGFSFLISGDLDHMKGQSKFGVGIMLSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NA14</accession>
    <name>A0A1C7NA14_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">40S ribosomal protein S29</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">RPS29_0</name>
        <name evidence="7" type="synonym">RPS29_1</name>
        <name evidence="7" type="ORF">A0J61_04429</name>
        <name evidence="6" type="ORF">A0J61_06020</name>
    </gene>
    <organism evidence="6 8">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 8" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the universal ribosomal protein uS14 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000344">
        <property type="protein sequence ID" value="OBZ85927.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="LUGH01000216">
        <property type="protein sequence ID" value="OBZ87533.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NA14"/>
    <dbReference type="FunCoup" id="A0A1C7NA14">
        <property type="interactions" value="347"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NA14"/>
    <dbReference type="InParanoid" id="A0A1C7NA14"/>
    <dbReference type="OrthoDB" id="10252683at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022627">
        <property type="term" value="C:cytosolic small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002181">
        <property type="term" value="P:cytoplasmic translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="4.10.830.10:FF:000002">
        <property type="entry name" value="40S ribosomal protein S29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.830.10">
        <property type="entry name" value="30s Ribosomal Protein S14, Chain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001209">
        <property type="entry name" value="Ribosomal_uS14"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018271">
        <property type="entry name" value="Ribosomal_uS14_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039744">
        <property type="entry name" value="RIbosomal_uS14_euk_arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043140">
        <property type="entry name" value="Ribosomal_uS14_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF004424">
        <property type="entry name" value="PRK05766.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12010">
        <property type="entry name" value="40S RIBOSOMAL PROTEIN S29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12010:SF2">
        <property type="entry name" value="40S RIBOSOMAL PROTEIN S29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00253">
        <property type="entry name" value="Ribosomal_S14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00527">
        <property type="entry name" value="RIBOSOMAL_S14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4 6" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009083"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OBZ85927.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OBZ87533.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="56" mass="6628" checksum="7772BAB39EA3EB4B" modified="2016-11-30" version="1">MVHANVWNSHPKSYGKGSRQCRVCAHRAGLIRKYNLNICRQCFREYASDIGFHKYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NA51</accession>
    <name>A0A1C7NA51_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="9">WD repeat-containing protein 24</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">wdr24</name>
        <name evidence="9" type="ORF">A0J61_06031</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000345">
        <property type="protein sequence ID" value="OBZ85920.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NA51"/>
    <dbReference type="FunCoup" id="A0A1C7NA51">
        <property type="interactions" value="337"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NA51"/>
    <dbReference type="InParanoid" id="A0A1C7NA51"/>
    <dbReference type="OrthoDB" id="60955at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061700">
        <property type="term" value="C:GATOR2 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005774">
        <property type="term" value="C:vacuolar membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016239">
        <property type="term" value="P:positive regulation of macroautophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1904263">
        <property type="term" value="P:positive regulation of TORC1 signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd16693">
        <property type="entry name" value="mRING-H2-C3H3C2_WDR24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037590">
        <property type="entry name" value="WDR24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049566">
        <property type="entry name" value="WDR59_RTC1-like_RING_Znf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46200">
        <property type="entry name" value="GATOR COMPLEX PROTEIN WDR24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46200:SF1">
        <property type="entry name" value="GATOR COMPLEX PROTEIN WDR24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17120">
        <property type="entry name" value="zf-RING_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 6" id="KW-0853">WD repeat</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4" id="KW-0863">Zinc-finger</keyword>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="101"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="191"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="domain" description="WDR59/RTC1-like RING zinc finger" evidence="8">
        <location>
            <begin position="642"/>
            <end position="689"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="471"/>
            <end position="490"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="475"/>
            <end position="490"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF17120"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OBZ85920.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="701" mass="79440" checksum="FB5D2E291CEEE75E" modified="2016-11-30" version="1">MEEYITRERLSGAINALSISPDGNAVVVAGREILKIYTVQAKGVSETLNLRAGSHFNLNYSSNDVKWGNNATKYKVATAATNGAIIIWDLNRIGKKAERVITEHSRAVNRICFQSDNGNILLSASQDGTMKCWDFRDPKSGAKYRFEGKSESVRDVQFNPVNSYEFAAAFETGTIQKWDMRNAKALYDRKVSAHNGPCLTVDWHPSGRLVASGGRDKTIKVWDLSSDNRRPIYTIRTMASVSRIQWRPGFESEIASCALLTDSRVHIWDIRRPHLAKYTFDVHDTTPTGFLWLNSDELLSVSKDKWFIRQNIKGSYRPLDLLKRNGMGWNVQGDIAFTIDKSSREQFVDENFVSKPLSEATKNWRRLGIKSTTEEEIIQYIPPQSCGIAHMPLFDFEAFSIFAENYIISSDNVPLACQINGELAWKMGRYRTAQTWRIIGMLYESDEAEPESFLHENMYDDPDTIEESSIKLDEKGEDEEGEDEIDEETEDLSEILDDASQASGEESNSINTNNTSIQLSSASSFDLKIPWNHESVIMDLLQYYTDQGDIQMCVTLYLVLEKYIEIDSERVEDWFTAYIDLLHRFKLWTTATSIMKACSIQAVRERNENATTVNIACNTCFKLVNGTSNGAWACDKCHRLLNPCTICHQTVRGLYVWCQGCNHGGHLTHMREWFAIESLCATGCGHTCVLQPLLSTLPTEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NBF1</accession>
    <name>A0A1C7NBF1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="8">3'-5' exonuclease eri1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">eri1</name>
        <name evidence="8" type="ORF">A0J61_05867</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000330">
        <property type="protein sequence ID" value="OBZ86079.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NBF1"/>
    <dbReference type="FunCoup" id="A0A1C7NBF1">
        <property type="interactions" value="295"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NBF1"/>
    <dbReference type="InParanoid" id="A0A1C7NBF1"/>
    <dbReference type="OrthoDB" id="448399at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000175">
        <property type="term" value="F:3'-5'-RNA exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031047">
        <property type="term" value="P:regulatory ncRNA-mediated gene silencing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06133">
        <property type="entry name" value="ERI-1_3'hExo_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051274">
        <property type="entry name" value="3-5_Exoribonuclease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047201">
        <property type="entry name" value="ERI-1_3'hExo-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013520">
        <property type="entry name" value="Ribonucl_H"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003034">
        <property type="entry name" value="SAP_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23044">
        <property type="entry name" value="3'-5' EXONUCLEASE ERI1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23044:SF61">
        <property type="entry name" value="3'-5' EXORIBONUCLEASE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00929">
        <property type="entry name" value="RNase_T"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02037">
        <property type="entry name" value="SAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00479">
        <property type="entry name" value="EXOIII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50800">
        <property type="entry name" value="SAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 8" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0540">Nuclease</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0943">RNA-mediated gene silencing</keyword>
    <feature type="domain" description="SAP" evidence="7">
        <location>
            <begin position="5"/>
            <end position="39"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50800"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OBZ86079.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="280" mass="32972" checksum="A60040E77C8B1181" modified="2016-11-30" version="1">MEPVNKVTTVESLRIALQQLGLNTKGHKPELKQRYRKALKKQIKEENNDKEQEIEVEVETNRSKQPFDYYLFFDVEATCEDKCGFSYPNEIIEFPVILVKSDSFEIVNEYRSYVKPTINSTLSDFCTKLTGITQSTVDQSPTFVEVLNDFQLFLAKYELFQQSSAAFVTVDGPFDIRDFITKQCLHSRIKRPAYFDIPWVNLRKTFKDFYHLKENKNINGMLTHLKMEFKGREHSGLDDARNLALIAQRMNQEGCVLETNCRFDKKLHQPYQKYRKRYVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NBL3</accession>
    <name>A0A1C7NBL3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Apoptosis-inducing factor A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">aifA</name>
        <name evidence="3" type="ORF">A0J61_05595</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000306">
        <property type="protein sequence ID" value="OBZ86358.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NBL3"/>
    <dbReference type="STRING" id="101091.A0A1C7NBL3"/>
    <dbReference type="InParanoid" id="A0A1C7NBL3"/>
    <dbReference type="OrthoDB" id="202203at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004174">
        <property type="term" value="F:electron-transferring-flavoprotein dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.167.10">
        <property type="entry name" value="Regulator of G-protein Signalling 4, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023753">
        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016137">
        <property type="entry name" value="RGS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036305">
        <property type="entry name" value="RGS_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044926">
        <property type="entry name" value="RGS_subdomain_2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43735">
        <property type="entry name" value="APOPTOSIS-INDUCING FACTOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43735:SF6">
        <property type="entry name" value="FAD_NAD(P)-BINDING DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00615">
        <property type="entry name" value="RGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00368">
        <property type="entry name" value="FADPNR"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00469">
        <property type="entry name" value="PNDRDTASEII"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48097">
        <property type="entry name" value="Regulator of G-protein signaling, RGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50132">
        <property type="entry name" value="RGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RGS" evidence="2">
        <location>
            <begin position="38"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="572"/>
            <end position="617"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="635"/>
            <end position="669"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="10"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="584"/>
            <end position="594"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="596"/>
            <end position="617"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50132"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ86358.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="773" mass="86085" checksum="B3F4318EE2827CC6" modified="2016-11-30" version="1">MRYTNTDAMSQRSLSSSSTYSSNSSSTGNNSFRSNQFTLTQVLSNPKMLHEFEFFLRQSWSHESLLFIEAMTQLRHETDSKIVENSLHRIYKTFLAPGSPFELNVTTQDQVRENIRSLQWAIVDRVDAVAILEETEVQVLDMLNAKLFEFLQFMDIPTGQAHLNHVQNYQVRVVIVGGGFTGFTVASILDQMPRFYVTLIDTKDSFEYTPGIVKKIVNPEQSSSLRVRHDAYVRNGRVIIGYAEHLSNKGKAISVNNEIVEFDYLVVATGSAYSSQLKSTDTSSLYRMTGLEESYFELLKAHKVLIIGGGLVGCELASEISQHQFPGPYPNKQITLVDSHPNVVSRSDVHQQNMALKYLQNLGVEVVCNERILDFDTSNQKSYLGSSGRVYSGYDKVFIATGTRPNSTLFGSATDDHSLDSCIDAWGRIKVKPTLQIDHYKYDHIFAGGDVTNVVEEKTGYAATISGVCIARNICRLVKGKAPLKQGTKGTLPAPLKPLHGMLENGGIGKPPKLYLENLNALKKRFSFLNPSWAALKYFDEQQFLKIVQGQGTIHSSQVLGRLPRKLDLPSKSTSLLQHARAMSTKSSVSSKASRQTHSNSTISNLSRGNGQTNINIQADVPTTNTLPVRSVSKHSLMKNRAATQQQRRHHEQTHSFSSSAGTSIEEESERAVQEFSFEKFTYGDEDIQLFSPAYHPVRNISSPLPHVVSQKNQILPDATSYGKGFALSPRPAARRRASLTTSFDRFSIYDSKSQPNIKLTRSASFSSITKTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NBU6</accession>
    <name>A0A1C7NBU6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF7789 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_05357</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000287">
        <property type="protein sequence ID" value="OBZ86592.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NBU6"/>
    <dbReference type="InParanoid" id="A0A1C7NBU6"/>
    <dbReference type="OrthoDB" id="2448307at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056691">
        <property type="entry name" value="DUF7789"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040410">
        <property type="entry name" value="UPF0658_Golgi"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34391">
        <property type="entry name" value="UPF0658 GOLGI APPARATUS MEMBRANE PROTEIN C1952.10C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34391:SF1">
        <property type="entry name" value="UPF0658 GOLGI APPARATUS MEMBRANE PROTEIN C1952.10C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25044">
        <property type="entry name" value="DUF7789"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="63"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="103"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="129"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="176"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="219"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="256"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="282"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="319"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="domain" description="DUF7789" evidence="2">
        <location>
            <begin position="209"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="376"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF25044"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ86592.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="376" mass="43445" checksum="1045F623AF77633B" modified="2016-11-30" version="1" fragment="single">MALYSHSSHSILSETNDKPRGLRLERQSTHVHKVTLLVLIFKQKMAHLSFSSFKSIWNTKNSLYLVLLTVFEAIVVIVLESVILARFKREVHVDIYQGLTKGIPVYLVIFIFSLVFQVALAWDAVRNRNTIQIIALILFNLCCFSYAAFQFKQVHRALQQRLGDNALSGELQKLMIANPIVIGICQLAYFYLGARLYLEFGWRIYKKIGADPDIRNMYRWYQIFLTILKIDFFFFLGFSIQYLVLVLQHGDIEYPLTIVALPLICVVLVVAVYAIKHESRRLIALFFLGLAAGIAYFIYKIYRIYDETQRPKYVYVNEFLTFFACVTLVLIVLTTVNAGICFYNFDKGLKAHLLRNMDEPYFGSEDEQGGRTLSLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NBU8</accession>
    <name>A0A1C7NBU8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">JmjC domain-containing histone demethylation protein 1</fullName>
            <ecNumber evidence="5">1.14.11.27</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="17">[Histone-H3]-lysine-36 demethylase 1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="23" type="primary">JHD1</name>
        <name evidence="23" type="ORF">A0J61_05395</name>
    </gene>
    <organism evidence="23 24">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="23 24" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="23 24">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Histone demethylase that specifically demethylates 'Lys-36' of histone H3, thereby playing a central role in histone code.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="18">
            <text>N(6),N(6)-dimethyl-L-lysyl(36)-[histone H3] + 2 2-oxoglutarate + 2 O2 = L-lysyl(36)-[histone H3] + 2 formaldehyde + 2 succinate + 2 CO2</text>
            <dbReference type="Rhea" id="RHEA:42032"/>
            <dbReference type="Rhea" id="RHEA-COMP:9785"/>
            <dbReference type="Rhea" id="RHEA-COMP:9787"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:16842"/>
            <dbReference type="ChEBI" id="CHEBI:29969"/>
            <dbReference type="ChEBI" id="CHEBI:30031"/>
            <dbReference type="ChEBI" id="CHEBI:61976"/>
            <dbReference type="EC" id="1.14.11.27"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the JHDM1 histone demethylase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="23">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.14.11.27" evidence="5"/>
    <dbReference type="EMBL" id="LUGH01000289">
        <property type="protein sequence ID" value="OBZ86565.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NBU8"/>
    <dbReference type="STRING" id="101091.A0A1C7NBU8"/>
    <dbReference type="InParanoid" id="A0A1C7NBU8"/>
    <dbReference type="OrthoDB" id="5876800at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140680">
        <property type="term" value="F:histone H3K36me/H3K36me2 demethylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd15517">
        <property type="entry name" value="PHD_TCF19_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.650">
        <property type="entry name" value="Cupin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041070">
        <property type="entry name" value="JHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050690">
        <property type="entry name" value="JHDM1_Histone_Demethylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003347">
        <property type="entry name" value="JmjC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019786">
        <property type="entry name" value="Zinc_finger_PHD-type_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001965">
        <property type="entry name" value="Znf_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019787">
        <property type="entry name" value="Znf_PHD-finger"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23123">
        <property type="entry name" value="PHD/F-BOX CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17811">
        <property type="entry name" value="JHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02373">
        <property type="entry name" value="JmjC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00558">
        <property type="entry name" value="JmjC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00249">
        <property type="entry name" value="PHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51184">
        <property type="entry name" value="JMJC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01359">
        <property type="entry name" value="ZF_PHD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50016">
        <property type="entry name" value="ZF_PHD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="11" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="13" id="KW-0408">Iron</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="16" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="24" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="15" id="KW-0804">Transcription</keyword>
    <keyword evidence="14" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="9" id="KW-0862">Zinc</keyword>
    <keyword evidence="8 19" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="PHD-type" evidence="21">
        <location>
            <begin position="5"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="domain" description="JmjC" evidence="22">
        <location>
            <begin position="204"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="20">
        <location>
            <begin position="466"/>
            <end position="506"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="20">
        <location>
            <begin position="520"/>
            <end position="611"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="20">
        <location>
            <begin position="496"/>
            <end position="506"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="20">
        <location>
            <begin position="520"/>
            <end position="529"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="20">
        <location>
            <begin position="545"/>
            <end position="557"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00003909"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00008037"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00013246"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00015153"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00031083"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00047915"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="21">
        <source>
            <dbReference type="PROSITE" id="PS50016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="22">
        <source>
            <dbReference type="PROSITE" id="PS51184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="EMBL" id="OBZ86565.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="24">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="611" mass="70304" checksum="5AB04B4EA30E724D" modified="2016-11-30" version="1">MVGTTTQCPYCPSSESVDSLEWIQCNACHVWYHSKCLQLDNVALIDRFHCPKCIQAHGPSTYKEPLQQRKSNRSQARLNYADLNEGKSTGDEQIWGKLLSVKSFAKDKFKRYKASDVNMQLLRSTGLKEPFVIERNEPELDMKMPSPNLDVYDIARLVGGDDLPVEVIDVATQSELPGWTMGRWANYFHSKKRDRIRNVISLEISGSDLADQITRPKIVRELDWIDLMWPVHDHPEEFPKVQLYCLMGTKNSYTDFHIDFGGSSVFYHILSGRKTFYFIEPTSTNLKKYQKWSSSSEQSTTFLGDLVKQCFSVELRAGNTMIIPSGWIHAVYTPEDAIVIGGNFLHTFGVATQLQVHEIEQATEVPLKFQFPYYRRLNWYALAKFDTWLMDEKKRKEFSYDELVNMALLASFLKSELIKSDAPMSEKGMITQHSRKAHQIPDSVSQPTVLAEHVLNLVKQAIAESDTLSSPKASKPKKSSQKISIKLSQPRQQTAYEEENDDDLEDEYEEDYFDKDDEEFEVEHDEDDIIPTSHHTQERKRRSRQKSESRKMSKIADESSSDEDDMGTRKKSNTAKSLSGLFSNRKRSSNTLMPKSTKQRLLDRISNSKKY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NBV9</accession>
    <name>A0A1C7NBV9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_05371</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000288">
        <property type="protein sequence ID" value="OBZ86575.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NBV9"/>
    <dbReference type="InParanoid" id="A0A1C7NBV9"/>
    <dbReference type="OrthoDB" id="2241281at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ86575.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="76" mass="8420" checksum="9C9B885E28D12976" modified="2016-11-30" version="1">MNSQGAKLEELVEKTHQASIEDIAVKAWVSSDAERKKVAEQANHIHEEATGHSMKIDEHGNIDIGCKEAKQCPKLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NBZ9</accession>
    <name>A0A1C7NBZ9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Mitochondrial zinc maintenance protein 1, mitochondrial</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_05431</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000292">
        <property type="protein sequence ID" value="OBZ86518.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NBZ9"/>
    <dbReference type="STRING" id="101091.A0A1C7NBZ9"/>
    <dbReference type="InParanoid" id="A0A1C7NBZ9"/>
    <dbReference type="OrthoDB" id="15893at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35763">
        <property type="entry name" value="COMPLEX 1 LYR-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35763:SF1">
        <property type="entry name" value="OS11G0133900 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13233">
        <property type="entry name" value="Complex1_LYR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="99"/>
            <end position="119"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ86518.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="119" mass="13531" checksum="A135B0B41881D02B" modified="2016-11-30" version="1">MSASRSLHVYRSLLRECNTQYTKGASNPFFANELKSIYRQNQHITDPSKITALNVNAENVLTFLTSSRKHKELRDIYSAIVLEQKKKIELSANRVGLNLPKEYDPSNPVPLAPEVEKTD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NCE8</accession>
    <name>A0A1C7NCE8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_05526</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000300">
        <property type="protein sequence ID" value="OBZ86429.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NCE8"/>
    <dbReference type="InParanoid" id="A0A1C7NCE8"/>
    <dbReference type="OrthoDB" id="2290754at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="43"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="210"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="43"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ86429.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="532" mass="62009" checksum="EA2619E49518CE0B" modified="2016-11-30" version="1">MAHFEIQTEIPTLFNQKQALPKQAFNGFVATDDDNTLVSPISSIDTCSSSSRRSSFSSLASSSPGNLIRHSRSLQLDHDKSILYPTKQSAYDRIEFLEEQLRIQHQFNETLLKNKSSTISNEFNSGLLDKMKGESSDTDRVMNKLQELKQLVTDYHVELSQNKDQSNPLQTKVYFSTQIIENWIQCVTQLNSLPTKQGLKNVMLPLLYRVEKEQNRNNRLVEGLNRLKQQKQTASKTTHQLKSRVTTLERTTEQLRQQLAKVNQQRKEETAEMEQVIEEMRQEMESMXDELDQLKAQKETAPLKSQEGPDYARIISTHAQQVEALEQEKKELRSRLIQAEQRTAAELDLLMAVEQTKNKSDQKELEEALKRTLAERDAELAKTKQELNKLKKQIDRVQQYNEKQIEREVNARLEELETQLRMAHQKDTDTYKLQISREVRDLSGQLVEFEAELQALERQHLQDQQSIENAIQSQFNVEETLRMEKSAWEKREHELRMNITKSEQRIISLEQEVLVLYSKNLDMAKHLCELEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7ND88</accession>
    <name>A0A1C7ND88_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Rap guanine nucleotide exchange factor 5</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">Rapgef5</name>
        <name evidence="5" type="ORF">A0J61_05227</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000277">
        <property type="protein sequence ID" value="OBZ86719.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7ND88"/>
    <dbReference type="STRING" id="101091.A0A1C7ND88"/>
    <dbReference type="InParanoid" id="A0A1C7ND88"/>
    <dbReference type="OrthoDB" id="546434at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005085">
        <property type="term" value="F:guanyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007265">
        <property type="term" value="P:Ras protein signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.840.10">
        <property type="entry name" value="Ras guanine-nucleotide exchange factors catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008937">
        <property type="entry name" value="Ras-like_GEF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023578">
        <property type="entry name" value="Ras_GEF_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001895">
        <property type="entry name" value="RASGEF_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036964">
        <property type="entry name" value="RASGEF_cat_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23113:SF368">
        <property type="entry name" value="CELL DIVISION CONTROL PROTEIN 25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23113">
        <property type="entry name" value="GUANINE NUCLEOTIDE EXCHANGE FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00617">
        <property type="entry name" value="RasGEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00147">
        <property type="entry name" value="RasGEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48366">
        <property type="entry name" value="Ras GEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50009">
        <property type="entry name" value="RASGEF_CAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0344">Guanine-nucleotide releasing factor</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ras-GEF" evidence="4">
        <location>
            <begin position="503"/>
            <end position="727"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="105"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="147"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="218"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="111"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="232"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="294"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="313"/>
            <end position="328"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022658"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00168"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50009"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OBZ86719.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="753" mass="86083" checksum="1A78C004CF6077FF" modified="2016-11-30" version="1">MTINSRCSHLVPPFTKNTNIFWGDEGLDEILTCQEFLAFNDEVKKKCSNTFDSSCKNENKLHTNYNSRKRHSNGSIIHKKEQLYSTLPPLPTMESFLTMMNMPSPPELPDLTARSTSSSASSSHSTINSLLLDDVSVRLAKVNLDSHSPLGKKEDHTPFNKPSKAISSKAPVLPAPPPVPPKDFCLLEMSSSSTNKFMKYINTHTDYRNEKSKLVLNEATSKKRRTTDMPKAGKKLLRAKSAQKRPPIPPRRSSMPSDVTTEQTDLSKLPFDATTQYRKPIPKPFDTSRREELSTISRKNNNNEAAKQTNMLDKSKEESKKSRKSDNKLLKLTENDQVVLLYEMIEGKLQVVAGTPQKLFEKLADEAVQDIEFVDTYLLNHFSFGDFKNDKKLQQRLDLFRFSDSVRLFQYQSDKINFALEAKTGKTSKAASLPFPIDSSFWDENYQPSIPQYIASRRLSDGLFSFESFDALSLTLTSPSLIDNKYHARFNLNSSHESLMSLDTKDVARYLTLADYQLFKSIHEHGIYNRKTSNSSIKTDHVQLMTKRANMLGHWVAHELCNLACLKPKRSFVKKLIDIAKMCYELNNFHTCMVITMGLESTPKLKEVWESLSNKDSSTFSLLQKLLDVNMNMRCYRQKIKQAKSPAIPFLPVVLKDYTFLNENPTFLSSYPDLINFSKFIFIKQFTDKTFGLLEEPYWFSGDLSHFPFLQQNQDKTAKGSLDDAANWVESRLDQVQNCYLHCDLLCNNNRAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7ND96</accession>
    <name>A0A1C7ND96_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Transcription elongation factor 1 homolog</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">ELF1</name>
        <name evidence="12" type="ORF">A0J61_04888</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 10">Transcription elongation factor implicated in the maintenance of proper chromatin structure in actively transcribed regions.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 10">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the ELOF1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000250">
        <property type="protein sequence ID" value="OBZ87051.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7ND96"/>
    <dbReference type="FunCoup" id="A0A1C7ND96">
        <property type="interactions" value="214"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7ND96"/>
    <dbReference type="InParanoid" id="A0A1C7ND96"/>
    <dbReference type="OrthoDB" id="445983at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008023">
        <property type="term" value="C:transcription elongation factor complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000993">
        <property type="term" value="F:RNA polymerase II complex binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006368">
        <property type="term" value="P:transcription elongation by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045815">
        <property type="term" value="P:transcription initiation-coupled chromatin remodeling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="FunFam" id="2.20.25.190:FF:000001">
        <property type="entry name" value="Transcription elongation factor 1 homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.25.190">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007808">
        <property type="entry name" value="Elf1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038567">
        <property type="entry name" value="T_Elf1_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20934">
        <property type="entry name" value="TRANSCRIPTION ELONGATION FACTOR 1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20934:SF0">
        <property type="entry name" value="TRANSCRIPTION ELONGATION FACTOR 1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05129">
        <property type="entry name" value="Zn_ribbon_Elf1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57783">
        <property type="entry name" value="Zinc beta-ribbon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-0251">Elongation factor</keyword>
    <keyword evidence="4 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9 10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 10" id="KW-0804">Transcription</keyword>
    <keyword evidence="7 10" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="6 10" id="KW-0862">Zinc</keyword>
    <keyword evidence="5 10" id="KW-0863">Zinc-finger</keyword>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="83"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="85"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="115"/>
            <end position="126"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU364033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="OBZ87051.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="126" mass="14836" checksum="3456E6BBC7E6C5E3" modified="2016-11-30" version="1">MGKRKTKRKPQKKLKEKLDTSFNCLFCNHESSIECKIDQQNKVGILTCKICDVNWQTTITYLDEPVDVYSAWIDACEEVNRQKKLQSQRARTQRNDSQSPSPPPRQNYNSNQLDPYDDEEEEDDDY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NDN4</accession>
    <name>A0A1C7NDN4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Zinc finger protein sfp1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">sfp1_1</name>
        <name evidence="8" type="ORF">A0J61_04746</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000239">
        <property type="protein sequence ID" value="OBZ87207.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NDN4"/>
    <dbReference type="STRING" id="101091.A0A1C7NDN4"/>
    <dbReference type="InParanoid" id="A0A1C7NDN4"/>
    <dbReference type="OrthoDB" id="3269380at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051580">
        <property type="entry name" value="ZnF-Chromatin_assoc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23057">
        <property type="entry name" value="JUXTAPOSED WITH ANOTHER ZINC FINGER PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23057:SF0">
        <property type="entry name" value="JUXTAPOSED WITH ANOTHER ZINC FINGER PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="7">
        <location>
            <begin position="210"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="7">
        <location>
            <begin position="252"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="125"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="16"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="143"/>
            <end position="152"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OBZ87207.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="304" mass="34204" checksum="9D488DC76CE0A482" modified="2016-11-30" version="1">MSSQNIPISFQRKHSLSTNGSSALSYSPSSHTMPAIFQHRDSFVHQRELESQFCSDLVCCGTRVKDLHELLHHYEEHHHAPIEEEPEPIAKEEDEEDDIMMEDIDTPLPTQPHELAALTSSPLLRQKPLPAASTPADLSPTMSVHPSPSVSQPLPPLSVTTNNAISNLPQHTDEILQKVLANAQQTHPELSYFRAEALYQTCDDGTDKPYKCPIANCEKAYKNPNGLKYHQMHGHSDEDTLSEAERDAQKPYMCTIGYCNKRYKNLNGLKYHIEHSHLAKLKHLNPMDGPSFADNSTLWSPTQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NDZ7</accession>
    <name>A0A1C7NDZ7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">3-hydroxy-3-methylglutaryl coenzyme A reductase</fullName>
            <shortName evidence="9">HMG-CoA reductase</shortName>
            <ecNumber evidence="9">1.1.1.34</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">hmgA_2</name>
        <name evidence="10" type="ORF">A0J61_04621</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>(R)-mevalonate + 2 NADP(+) + CoA = (3S)-3-hydroxy-3-methylglutaryl-CoA + 2 NADPH + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:15989"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:36464"/>
            <dbReference type="ChEBI" id="CHEBI:43074"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.1.1.34"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="9">Metabolic intermediate biosynthesis; (R)-mevalonate biosynthesis; (R)-mevalonate from acetyl-CoA: step 3/3.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Endoplasmic reticulum membrane</location>
            <topology evidence="1 9">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the HMG-CoA reductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.34" evidence="9"/>
    <dbReference type="EMBL" id="LUGH01000230">
        <property type="protein sequence ID" value="OBZ87327.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NDZ7"/>
    <dbReference type="STRING" id="101091.A0A1C7NDZ7"/>
    <dbReference type="InParanoid" id="A0A1C7NDZ7"/>
    <dbReference type="OrthoDB" id="310654at2759"/>
    <dbReference type="UniPathway" id="UPA00058">
        <property type="reaction ID" value="UER00103"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005778">
        <property type="term" value="C:peroxisomal membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004420">
        <property type="term" value="F:hydroxymethylglutaryl-CoA reductase (NADPH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015936">
        <property type="term" value="P:coenzyme A metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006696">
        <property type="term" value="P:ergosterol biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008299">
        <property type="term" value="P:isoprenoid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00643">
        <property type="entry name" value="HMG-CoA_reductase_classI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.3270.10:FF:000001">
        <property type="entry name" value="3-hydroxy-3-methylglutaryl coenzyme A reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.420:FF:000001">
        <property type="entry name" value="3-hydroxy-3-methylglutaryl coenzyme A reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.770.10">
        <property type="entry name" value="3-hydroxy-3-methylglutaryl-coenzyme A Reductase, Chain A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3270.10">
        <property type="entry name" value="HMGR, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.420">
        <property type="entry name" value="Hydroxymethylglutaryl-CoA reductase, class I/II, NAD/NADP-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002202">
        <property type="entry name" value="HMG_CoA_Rdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023074">
        <property type="entry name" value="HMG_CoA_Rdtase_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023076">
        <property type="entry name" value="HMG_CoA_Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004554">
        <property type="entry name" value="HMG_CoA_Rdtase_eu_arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023282">
        <property type="entry name" value="HMG_CoA_Rdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009023">
        <property type="entry name" value="HMG_CoA_Rdtase_NAD(P)-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009029">
        <property type="entry name" value="HMG_CoA_Rdtase_sub-bd_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00533">
        <property type="entry name" value="HMG_CoA_R_NADP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10572">
        <property type="entry name" value="3-HYDROXY-3-METHYLGLUTARYL-COENZYME A REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10572:SF24">
        <property type="entry name" value="3-HYDROXY-3-METHYLGLUTARYL-COENZYME A REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00368">
        <property type="entry name" value="HMG-CoA_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00071">
        <property type="entry name" value="HMGCOARDTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55035">
        <property type="entry name" value="NAD-binding domain of HMG-CoA reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56542">
        <property type="entry name" value="Substrate-binding domain of HMG-CoA reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00066">
        <property type="entry name" value="HMG_COA_REDUCTASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00318">
        <property type="entry name" value="HMG_COA_REDUCTASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50065">
        <property type="entry name" value="HMG_COA_REDUCTASE_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 9" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 9" id="KW-0521">NADP</keyword>
    <keyword evidence="7 9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="21"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="10">
        <location>
            <position position="465"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007661"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU361219"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OBZ87327.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="465" mass="50179" checksum="DBAC68E584151109" modified="2016-11-30" version="1" fragment="single">MKSSFKSLFDIYAVYIQHPVFSKWFILAFVLSLFLNTYLLNASKQQPKVIIKKVIERVEVPSKEQPKSVTKPSKKHLAYNHSDVIRPLDEVLGLLGTPEALTDEEIISVVQAGKMAPYALEKVLGDLERAVHIRRALISRDSRTRTLEDSMLPVKNYHYDKVMGACCENVIGYMPIPVGVAGPLVIDGDSIHIPMATTEGCLVASTARGCKAINAGGGANTIVVADGMTRGPCVEFPTITRAADCKRWIEQEGEKIVTEAFNSTSRFARVRKLKVAVAGRLVYIRFSTTTGDAMGMNMISKGCEKALSKIAERYPDMQIISLSGNYCTDKKPAAINWIEGRGKSVVAEAVIPGAVVEKVLKTTVSALVELNISKNLVGSAMAGSVGGFNAHAANILTAIYLATGQDPAQNVESSNCITLMKAVNGEKDLHISCTMPCIEVGTIGGGTILPPQQAMLDFIGVRGPH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NEA9</accession>
    <name>A0A1C7NEA9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Pre-rRNA-processing protein TSR2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">TSR2</name>
        <name evidence="4" type="ORF">A0J61_04523</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the TSR2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000223">
        <property type="protein sequence ID" value="OBZ87427.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NEA9"/>
    <dbReference type="FunCoup" id="A0A1C7NEA9">
        <property type="interactions" value="405"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NEA9"/>
    <dbReference type="InParanoid" id="A0A1C7NEA9"/>
    <dbReference type="OrthoDB" id="263560at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043022">
        <property type="term" value="F:ribosome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000463">
        <property type="term" value="P:maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000462">
        <property type="term" value="P:maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019398">
        <property type="entry name" value="Pre-rRNA_process_TSR2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21250">
        <property type="entry name" value="PRE-RRNA-PROCESSING PROTEIN TSR2 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10273">
        <property type="entry name" value="WGG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0698">rRNA processing</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="120"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="129"/>
            <end position="164"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006524"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OBZ87427.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="170" mass="19496" checksum="35DC9872040FD9D1" modified="2016-11-30" version="1">MADHPNKLAFEEGARYIFNNWTALRLAVEQDWGGVESPEKKEWFIDVVIDYFAKQGKKLDVDDIEAVLSQVMSDEFHTTLEDDSPYLVAKHLYELFNQCIHGNYTEVERLREKAKSQNAYIGSSMGQGDDSDSGDDDQDDQEEGGDDEPMEETPQEPLVDEDGWEIVRRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NF13</accession>
    <name>A0A1C7NF13_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_04237</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000203">
        <property type="protein sequence ID" value="OBZ87702.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NF13"/>
    <dbReference type="STRING" id="101091.A0A1C7NF13"/>
    <dbReference type="InParanoid" id="A0A1C7NF13"/>
    <dbReference type="OrthoDB" id="2283025at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="42"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="155"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="266"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="54"/>
            <end position="90"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ87702.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="546" mass="61397" checksum="E9D9BB648EB1E03B" modified="2016-11-30" version="1">MEQQDTPKWRKKPQGSESQRKVDKELQRIKSLAVVSVLNKSFQDITPPLPPAMSPSSSLTTSSSEQSSPSYKARSRSVSSTSSTITKTIVNRPISTVHLPSHSVQKCETTTDKDKTPSLPTQPLPPPTTTTTTLSGQKDNSVAEKELSHDDLVTRSHIDEEKEVLQKRLAELQTLYDQSHQEADQLREQQKTQCQLLILQDKLIQEMTDHIEDLNTNSPVLDDGICHSETEEKVMALLPKAQEDLSWLQTELEQLMPLKTKYESFISDMTLQLKAYDQKADELETLAREIQKESRAQTLYIDAKVQALVNKVLERNEVISRLQYQMHTEKQLLPKIDNTSSISTKSAAESTHGGIWEQYTHEFSGGTGNSTRSSMASTDTAPSRIYTSRWKGNHIPPASPPPSLPLPPIPNSSVISRPKSIVSEVSEYSNTKSNKHVSIDAVGGSTLRRSSHQSEKVDTEMIDAIKAAEAMSVTEATSAAEAAYYKEFTEQLHARLSISKEIDDLRVWQPTDFEEIQKKLQSEYWPEISEKDQHAFWKGMKKKLRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NF28</accession>
    <name>A0A1C7NF28_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Anucleate primary sterigmata protein A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">apsA_1</name>
        <name evidence="4" type="ORF">A0J61_04794</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000242">
        <property type="protein sequence ID" value="OBZ87166.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NF28"/>
    <dbReference type="InParanoid" id="A0A1C7NF28"/>
    <dbReference type="OrthoDB" id="2149224at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005938">
        <property type="term" value="C:cell cortex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005543">
        <property type="term" value="F:phospholipid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015631">
        <property type="term" value="F:tubulin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032065">
        <property type="term" value="P:maintenance of protein location in cell cortex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000226">
        <property type="term" value="P:microtubule cytoskeleton organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053005">
        <property type="entry name" value="Nuclear_Pos-Cytoskel_Interact"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024774">
        <property type="entry name" value="PH_dom-Mcp5-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001849">
        <property type="entry name" value="PH_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28190">
        <property type="entry name" value="NUCLEAR MIGRATION PROTEIN NUM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28190:SF1">
        <property type="entry name" value="NUCLEAR MIGRATION PROTEIN NUM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12814">
        <property type="entry name" value="Mcp5_PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00233">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50003">
        <property type="entry name" value="PH_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PH" evidence="3">
        <location>
            <begin position="1394"/>
            <end position="1502"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="97"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="278"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="318"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="421"/>
            <end position="505"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1207"/>
            <end position="1360"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1505"/>
            <end position="1541"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="765"/>
            <end position="792"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="940"/>
            <end position="1040"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="338"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="355"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="436"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="473"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1249"/>
            <end position="1263"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1264"/>
            <end position="1274"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1281"/>
            <end position="1290"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1301"/>
            <end position="1316"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1333"/>
            <end position="1360"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1513"/>
            <end position="1541"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OBZ87166.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="1580" mass="177533" checksum="959C8765660500E9" modified="2016-11-30" version="1">MSRLLKKSSGTDLKQKRPVSFAGKSIQQVKLELTAQLNEKEKALEKTGMSPISRNALIKQTEAIKTEINALDGYQKEDELPTDVRLKLEDLANEFQGLKGTKSTGLDDPSPRGPSTSFSPLLPPPPTNSSPTKRTKTVNGNKRNPDIEFATEIGQNLLNEVRKLHTDLQEKEEIIKQLQSSQANAERLQESVERQLKQREEIEERLKEENWNLEVANQELRSSLLESNQAIAKHNTEFSKLAKQLKNQSEQIEIMKAQEEKSTSVIEAMKARHEQETYQLRKHAANAQRENTQAQKQVEALQTELKIHKAKLAIRMTVSSRTDETKSADTTQDDNQDQDNNQDQTNTKGPILAPSVSQSNRSQALETETLKQSLAHAHRIISNLRSSIHKEKVEKFELKKMLSDSQENIEQMRKEMASWNQNNAMGMGGGQGRSKSGGKRKGKSAKKRRGGVGRQPRGLVANDSDAELKSISADEETEEDEELSSEETGDEEDSMHGDALDPEFSFVPAGNTLGSFMEFSSAPFGSNSMKPLSSELELNNKTETVDIGINTEPVHSADHTPFVQADHPILVQEQISQALVRERRAIFERAQPILSAEQIQVILPNRHLEEQHNKGHELNVQDTQDTTQYTEKEVTHAMIPKSDVDRLVQEAVETKTATMIPKLEADEWVHKARHETRSEVEQELSLSMIPKAEAEVMVHEAMQKTRGELEVAHQEQLRDMAIKADNRVQEAVATTTKQLRQAFDSEKKKMEQDIERDMVTKIKAADMVQEATENLRSEFEQEKKQRDEEERVKLNKFAESLTNDMISKQDAEKLAQKAALEERGKVETEMNKWMDKQKSEIESSKQAKIEQLEVAHASALESQKSEMMTVQKAELERFSLEMSIKHKTELEEQEKKLKMSQTEELNKQRLEIESVMGDALEKLKVEMKATQQAALERCQSESDSLRLSELERQKAELEEVKVKALDQQKEELEALKVKEVQDQQTQWEAKKAELEAAEAARMNELQSSKKAEIDALSKRIESYKKEQEETLRRMKNMLTKESVDVLVKRAVAEVQEAAEKNQAEALAGMISKEYAKRMVEDEVAKALEAERKDVAEREAAESLEMISKAEAEALAKVAAADAIVKERQAAAARESELVTKEEVKVLTETAVREALEKERAESAAVLTKERKMFKEKEEQMITKEQAEKDIKHAVQQALAEYQQTHVVEKPSHTLAHLSVKSETPKPSRSKTQRSSTTPSELAPEISLERSVSTSRINLPSVNVTPAPSASTPAHSSRRLRLSSSVSSLRLGNKKEGDAKQSKAQNAEANPSNSSFGSLRILDKSKYQSHRLQSRSTTSLREVSNKQHSTTSVSTMSSGDDQTVNQVYSEEGFSGFPSSGSGGATDAYIISAITQTMIGEWMSKHTRRYVGGGISENKHKRYFWVHPYTKILYWSPEKPGAEGNQAKTKSAYIESLSVVPSHDHTGASTISLLIHTPKRDLKITAPSSERHDIWYKSLSYLLGRSTEASEETSTRLTNDSSSTIDNAGHQQGTKPSDMNVSNDAEVTQYDSDESEDLVNIRQCCDGKHDLSTLSRGHHHHH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NF96</accession>
    <name>A0A1C7NF96_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">BZIP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">A0J61_04215</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000201">
        <property type="protein sequence ID" value="OBZ87728.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NF96"/>
    <dbReference type="STRING" id="101091.A0A1C7NF96"/>
    <dbReference type="InParanoid" id="A0A1C7NF96"/>
    <dbReference type="OrthoDB" id="1939598at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001228">
        <property type="term" value="F:DNA-binding transcription activator activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000977">
        <property type="term" value="F:RNA polymerase II transcription regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd14705">
        <property type="entry name" value="bZIP_Zip1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.170">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004827">
        <property type="entry name" value="bZIP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046347">
        <property type="entry name" value="bZIP_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13044">
        <property type="entry name" value="ACTIVATING TRANSCRIPTION FACTOR ATF 4/5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13044:SF14">
        <property type="entry name" value="CRYPTOCEPHAL, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07716">
        <property type="entry name" value="bZIP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57959">
        <property type="entry name" value="Leucine zipper domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50217">
        <property type="entry name" value="BZIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00036">
        <property type="entry name" value="BZIP_BASIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="BZIP" evidence="8">
        <location>
            <begin position="250"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="105"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="188"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="275"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="206"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="221"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="239"/>
            <end position="250"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OBZ87728.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="340" mass="38288" checksum="7443DE4569323586" modified="2016-11-30" version="1">MNSNNSSIEDQWLSSLNLIMDPVSVLSDAELQKELSVFADAQFTYDIAPGVAIKEAQSANNKRKSHHQPDMHSLLNVKLASLSENSYHTTMSPDAIAKFYDESPDCSPPNGYHSANPSPPNGFYSPNPTPPNGLHLSSNPASTNTYFQDILNPPITFYEEDALDAQDALDAQDDDQFLKTMSILTSHSEPNLPEVQDVPVDEQPRTKKRSNVRTKKSSEPLQEDNLESIDAETALTAGKKSQQGISSHTPLSKEDKRRRNTAASARFRVKKKLREQALQQTADEMTEKAKAYENRVLELEREVKWLKELIIERKDGRLEQLLMQQFAQQYHSSNSNSEYH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NFH4</accession>
    <name>A0A1C7NFH4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="8">NADH kinase pos5, mitochondrial</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">pos5</name>
        <name evidence="8" type="ORF">A0J61_04106</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the NAD kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000193">
        <property type="protein sequence ID" value="OBZ87852.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="FunCoup" id="A0A1C7NFH4">
        <property type="interactions" value="5"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NFH4"/>
    <dbReference type="InParanoid" id="A0A1C7NFH4"/>
    <dbReference type="OrthoDB" id="24581at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003951">
        <property type="term" value="F:NAD+ kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042736">
        <property type="term" value="F:NADH kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034599">
        <property type="term" value="P:cellular response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016226">
        <property type="term" value="P:iron-sulfur cluster assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019674">
        <property type="term" value="P:NAD+ metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006741">
        <property type="term" value="P:NADP+ biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.200.30:FF:000009">
        <property type="entry name" value="Poly(P)/ATP NAD kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10330">
        <property type="entry name" value="Probable inorganic polyphosphate/atp-NAD kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.200.30">
        <property type="entry name" value="Probable inorganic polyphosphate/atp-NAD kinase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00361">
        <property type="entry name" value="NAD_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017438">
        <property type="entry name" value="ATP-NAD_kinase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017437">
        <property type="entry name" value="ATP-NAD_kinase_PpnK-typ_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016064">
        <property type="entry name" value="NAD/diacylglycerol_kinase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002504">
        <property type="entry name" value="NADK"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20275">
        <property type="entry name" value="NAD KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20275:SF26">
        <property type="entry name" value="NADH KINASE POS5, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01513">
        <property type="entry name" value="NAD_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20143">
        <property type="entry name" value="NAD_kinase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111331">
        <property type="entry name" value="NAD kinase/diacylglycerol kinase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 8" id="KW-0418">Kinase</keyword>
    <keyword evidence="7" id="KW-0520">NAD</keyword>
    <keyword evidence="6" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OBZ87852.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="404" mass="45832" checksum="DE815AF193EC3859" modified="2016-11-30" version="1">MSTTSRFLLPFTCKFIHTKKXRLLPASIQLYHTGILRKTSILPNKVSLRLSKDHEKENDDIEKHLEMTRPRRESDILQVPGSTYGGLYQLKWNQAPRNVLIIKKPNDAKTEKALVQMANWLHQTRPELNIIMEPEEAERFQKELPFIHVIEPSKVEEYTRTVDFAITLGGDGTMLHLASLFPKAAPPVISFSLGTLCFLMSYNFEKYQHVLNDIMAGNVGLMMRMRLFCSLHQPNGKRIEVNGVEVGDRQVMNEVTLHRGRYPHLTSVDCFVDNHHLTECIADGLIVSTPTGSTAYSLSAGGPIVHPSVQSLLLTPICPRSLSFRTVLLPPSSTIELKIGEKSRSEIEVSMDGQEIFLLHKGEYVKVRMSKYPIPCVTQINSETSWEKDINDLLKWNQTFGANR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NFY4</accession>
    <name>A0A1C7NFY4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Serine hydroxymethyltransferase</fullName>
            <ecNumber evidence="9">2.1.2.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">SHM1</name>
        <name evidence="11" type="ORF">A0J61_04015</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Interconversion of serine and glycine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 9">
            <text>(6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + glycine + H2O = (6S)-5,6,7,8-tetrahydrofolate + L-serine</text>
            <dbReference type="Rhea" id="RHEA:15481"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15636"/>
            <dbReference type="ChEBI" id="CHEBI:33384"/>
            <dbReference type="ChEBI" id="CHEBI:57305"/>
            <dbReference type="ChEBI" id="CHEBI:57453"/>
            <dbReference type="EC" id="2.1.2.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 8 9">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3 9">One-carbon metabolism; tetrahydrofolate interconversion.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 9">Belongs to the SHMT family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.2.1" evidence="9"/>
    <dbReference type="EMBL" id="LUGH01000187">
        <property type="protein sequence ID" value="OBZ87928.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NFY4"/>
    <dbReference type="FunCoup" id="A0A1C7NFY4">
        <property type="interactions" value="755"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NFY4"/>
    <dbReference type="InParanoid" id="A0A1C7NFY4"/>
    <dbReference type="OrthoDB" id="10265628at2759"/>
    <dbReference type="UniPathway" id="UPA00193"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004372">
        <property type="term" value="F:glycine hydroxymethyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019264">
        <property type="term" value="P:glycine biosynthetic process from serine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035999">
        <property type="term" value="P:tetrahydrofolate interconversion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd00378">
        <property type="entry name" value="SHMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.640.10:FF:000097">
        <property type="entry name" value="Serine hydroxymethyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00051">
        <property type="entry name" value="SHMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001085">
        <property type="entry name" value="Ser_HO-MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049943">
        <property type="entry name" value="Ser_HO-MeTrfase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019798">
        <property type="entry name" value="Ser_HO-MeTrfase_PLP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039429">
        <property type="entry name" value="SHMT-like_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF000586">
        <property type="entry name" value="PRK00011.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11680">
        <property type="entry name" value="SERINE HYDROXYMETHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11680:SF28">
        <property type="entry name" value="SERINE HYDROXYMETHYLTRANSFERASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00464">
        <property type="entry name" value="SHMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000412">
        <property type="entry name" value="SHMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00096">
        <property type="entry name" value="SHMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="5 9" id="KW-0554">One-carbon metabolism</keyword>
    <keyword evidence="7 8 9" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 9 11" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Serine hydroxymethyltransferase-like" evidence="10">
        <location>
            <begin position="42"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="8">
        <location>
            <position position="283"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00006376"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR000412-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU000585"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="OBZ87928.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="511" mass="56885" checksum="D30BEC5656A5E7EB" modified="2016-11-30" version="1">MLRSLASSTIRPNALRLARPIVQVSRGYVFPAGQQEFLNERLENLDPEIFDIIEREKKRQQEGIDLIPSESQHHKKLDAYNFTSRAVMDALGSVMQNKYSEGYPGARYYGGNEFIDMSENLCRKRALEAFDLNDQAWGVNVQPLSGAPANLYVYGALLKPHDRIMGLDLPHGGHLSHGYQIPNKKISQVSAYFETLPYRLDEATGRIDYDALEKNAMLYRPKIIVAGASAYSRNIDYARMRQIADKCGAYLMADIAHISGLIAANVLPGPFEYADVVTTTTHKSLRGPRGAMIFFRKGVRSTDKKGREIHYDLENPINQSVFPGHQGGPHNHTITALAVALKQAKSPLFKEYQTQVLKNNAAFADRFNQLKYNLVSGGTDNHLLLVDLNSKGIDGARVERVLELANIAANKNTVPGDRSALIPGGVRMGTPAMTSRGFKEDDFVRVADFFDKAVKIAQEEKAKVDGKKLIDFKNHIGDGLSIESIQSLKKEVSQFASGFPTVGFWESEMKY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NH06</accession>
    <name>A0A1C7NH06_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Gamma-butyrobetaine dioxygenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">BBOX1</name>
        <name evidence="11" type="ORF">A0J61_03680</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>L-ascorbate</name>
            <dbReference type="ChEBI" id="CHEBI:38290"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the gamma-BBH/TMLD family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000163">
        <property type="protein sequence ID" value="OBZ88270.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NH06"/>
    <dbReference type="STRING" id="101091.A0A1C7NH06"/>
    <dbReference type="InParanoid" id="A0A1C7NH06"/>
    <dbReference type="OrthoDB" id="406634at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016706">
        <property type="term" value="F:2-oxoglutarate-dependent dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045329">
        <property type="term" value="P:carnitine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00250">
        <property type="entry name" value="CAS_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.2020.30:FF:000002">
        <property type="entry name" value="Putative gamma-butyrobetaine dioxygenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.130.10:FF:000001">
        <property type="entry name" value="Trimethyllysine dioxygenase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2020.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.130.10">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050411">
        <property type="entry name" value="AlphaKG_dependent_hydroxylases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010376">
        <property type="entry name" value="GBBH-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038492">
        <property type="entry name" value="GBBH-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042098">
        <property type="entry name" value="TauD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003819">
        <property type="entry name" value="TauD/TfdA-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10696">
        <property type="entry name" value="GAMMA-BUTYROBETAINE HYDROXYLASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10696:SF25">
        <property type="entry name" value="OXIDOREDUCTASE AIM17-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06155">
        <property type="entry name" value="GBBH-like_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02668">
        <property type="entry name" value="TauD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0124">Carnitine biosynthesis</keyword>
    <keyword evidence="6 11" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="8" id="KW-0408">Iron</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Gamma-butyrobetaine hydroxylase-like N-terminal" evidence="10">
        <location>
            <begin position="34"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="domain" description="TauD/TfdA-like" evidence="9">
        <location>
            <begin position="156"/>
            <end position="397"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001961"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008654"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022873"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF02668"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF06155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="OBZ88270.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="418" mass="48167" checksum="76BF1DC786A2E84E" modified="2016-11-30" version="1">MLPFTRSFLRNQRILASQTRIASRFNSTLGQITSTDKDSLKFKWQDQLEDSTYSYLWLRDNCPCENCLHPSSRQKLHSSADIPLDIKPVDIQVTAQHAEITWSSPLRGRQETSPHVSRFSLEFLQRYQSKESSQKFRFGHLKPQTWAANEYELDWVSYDDYMNSDEGLNTVVQRLYKTGLVFMKDVPLEDSSVTRVAERIGPVQETFYGRDFDVKNVAKSINIAYTSLYLGFHMDLMYMDSPPGIQLLHSLKNTVTGGASIFVDSFRAVELLKKDDPEAYEILRKTPVTFHYLNNGHHMYYKRPTIVTDEAHSGPAWDSHVNYAPQFQGPLDDLSPEEAKRFYGAFQKFADCIQQDSLRYQLTLKPGELVLFANRRVLHGRTSFDPTSGDRHLKGTYLNLDSLKDKLRVLSAQFGYHS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-06-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NHD4</accession>
    <name>A0A1C7NHD4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_03412</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000146">
        <property type="protein sequence ID" value="OBZ88533.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NHD4"/>
    <dbReference type="InParanoid" id="A0A1C7NHD4"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ88533.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="73" mass="8349" checksum="CDA80525627683CB" modified="2016-11-30" version="1">MCAFDNKIISNIDINRELRKKIPSNQCLLQLGLGLIQEKYLSFLFEANVPLWSTQVLLPSNLIFALFPSKHTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NHF9</accession>
    <name>A0A1C7NHF9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Cytochrome P450</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">A0J61_03504</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1 8">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000152">
        <property type="protein sequence ID" value="OBZ88448.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NHF9"/>
    <dbReference type="STRING" id="101091.A0A1C7NHF9"/>
    <dbReference type="InParanoid" id="A0A1C7NHF9"/>
    <dbReference type="OrthoDB" id="1470350at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050196">
        <property type="entry name" value="Cytochrome_P450_Monoox"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24291:SF50">
        <property type="entry name" value="BIFUNCTIONAL ALBAFLAVENONE MONOOXYGENASE_TERPENE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24291">
        <property type="entry name" value="CYTOCHROME P450 FAMILY 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 7 8" id="KW-0349">Heme</keyword>
    <keyword evidence="5 7 8" id="KW-0408">Iron</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 7 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 8" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="4 8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="38"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="7">
        <location>
            <position position="475"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OBZ88448.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="12">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="531" mass="61839" checksum="CEAB60B98257DF4C" modified="2016-11-30" version="1">MSRSMIQICSVLKESIWNTLSFYNHVIVSKVQNKNRKWIISTAIALSFAYFIRSRVFYPPKRFRHLPHTSTFQMILSVLRKDSIFEYNRKHVQPLFEKNDTRGLYTRLGPTGWEVYVSNLEDAKQVLFKLDTFPKTDEFKESKDTLGNKFSVGQNIFIANGHEWKKQRSIANSAFHRSMPIIMFGELVETLFRTMELMDDTIEVTSLLRRYTLDAIGKAAFGFDFHATEDPNSQWVVCYDAINVAFQDPLFLLFPILEQKFLWMFPKRKAIHDQLDLFLEMMDDIILNKRKEIQADKKHQNEAEKDLLTLMIEAEQRGEGVMTNKVLKGNLCFFFLAGHDTTTNALSFALYFLAVYPDVQERARKEVLTILGEDRIPTFEQIKAMTYLTQVIKETLRLYPPAPRIFPRYAQEDIALSGCMIPKGTHVIVDLHGLQRDENVWKDADRFNPDRFSEENDALTKNATWIPFSTGGRQCLGMNFSLTEQRVVLSMLLRKYEWSLPKESPHRDHVLTAGTFLVGPKDLDITFKKRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NHH4</accession>
    <name>A0A1C7NHH4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Mitochondrial adapter protein MCP1 transmembrane domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_03478</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000151">
        <property type="protein sequence ID" value="OBZ88475.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NHH4"/>
    <dbReference type="STRING" id="101091.A0A1C7NHH4"/>
    <dbReference type="InParanoid" id="A0A1C7NHH4"/>
    <dbReference type="OrthoDB" id="10259513at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055088">
        <property type="term" value="P:lipid homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039960">
        <property type="entry name" value="MCP1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012472">
        <property type="entry name" value="MCP1_TM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38409">
        <property type="entry name" value="MDM10-COMPLEMENTING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38409:SF1">
        <property type="entry name" value="MITOCHONDRIAL ADAPTER PROTEIN MCP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07950">
        <property type="entry name" value="MCP1_TM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="30"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="74"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="109"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="151"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="211"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="domain" description="Mitochondrial adapter protein MCP1 transmembrane" evidence="2">
        <location>
            <begin position="114"/>
            <end position="228"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07950"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ88475.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="252" mass="28303" checksum="F5F990B69A1A02E5" modified="2016-11-30" version="1">MTSSIGTTPRPFLTSQKAYQLLTKVQNASAIAFTTFSILHGAQIIAANIGGARLSNHWILLGRPFYQDQHTEGLLVTGAGLLHVLAGLSKYGLRVYWKQPTNNTHRAMGYLLIPLMGLHYYLVRYLPIQYYGDSSFIDFGYVAWGLQNRPVITYSLHTALILTATYHIVGGIQKLRQKPIQTPPSVPQHGHNITHQKIEGQLRHKRRLQKSVIAGISIALLSGMVIIGLDTKKIPLRHDFEQMYNTLSLFKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NHY0</accession>
    <name>A0A1C7NHY0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_03216</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000134">
        <property type="protein sequence ID" value="OBZ88737.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NHY0"/>
    <dbReference type="InParanoid" id="A0A1C7NHY0"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="54"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ88737.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="73" mass="8425" checksum="E7F250794D8EDAF3" modified="2016-11-30" version="1">MDSDIVRIYCQVTFFSGFDDRCIQVSDRIVKPNFGSPLPAKPLKIFLTTRRFELVLLWIVVGTTMLTIKGLRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NI04</accession>
    <name>A0A1C7NI04_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Replication factor A protein 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">ssb2_0</name>
        <name evidence="6" type="ORF">A0J61_03197</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the replication factor A protein 2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000133">
        <property type="protein sequence ID" value="OBZ88757.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NI04"/>
    <dbReference type="STRING" id="101091.A0A1C7NI04"/>
    <dbReference type="InParanoid" id="A0A1C7NI04"/>
    <dbReference type="OrthoDB" id="25571at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000781">
        <property type="term" value="C:chromosome, telomeric region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005662">
        <property type="term" value="C:DNA replication factor A complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035861">
        <property type="term" value="C:site of double-strand break"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000724">
        <property type="term" value="P:double-strand break repair via homologous recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006289">
        <property type="term" value="P:nucleotide-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040260">
        <property type="entry name" value="RFA2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014892">
        <property type="entry name" value="RPA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13989">
        <property type="entry name" value="REPLICATION PROTEIN A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13989:SF16">
        <property type="entry name" value="REPLICATION PROTEIN A2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08784">
        <property type="entry name" value="RPA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Replication protein A C-terminal" evidence="5">
        <location>
            <begin position="185"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="249"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007815"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF08784"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OBZ88757.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="249" mass="27948" checksum="6055E6455F4FCB09" modified="2016-11-30" version="1" fragment="single">NASSSKHSRLRRIILNNVKNQDDAKTKEKPTARTERSLRPITIKQAVNALMEDEDHFLVDGVAVYNVCLVGAIRCISQFDTFATILIEDGTGCIDLKIRNEPALDSKEDVLSVLKADQTHIDNRIGIHIKAIGRLKYACNKLLVAVTHIRLIEDMNEFTFQMLDAIHHHLTLIKKAPVVDKSLTLSSDILSTVKKEIKECSGKDGTHIQVICQNLSSVMDESKIIEAIEELMFEGQVYRVTNELIKTTD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NI97</accession>
    <name>A0A1C7NI97_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_04892</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000250">
        <property type="protein sequence ID" value="OBZ87064.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NI97"/>
    <dbReference type="STRING" id="101091.A0A1C7NI97"/>
    <dbReference type="InParanoid" id="A0A1C7NI97"/>
    <dbReference type="OrthoDB" id="20273at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="137"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="30"/>
            <end position="48"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ87064.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="305" mass="34957" checksum="C28E1ADE2A0AD274" modified="2016-11-30" version="1">MYQENQHQQINDPYRANRNSPFADPPYAPSEQSMPYTHSHTGSISNYSHHQDPYSRKKTSPLQQQYRPNTPLPNTDPIYPDQELPSFDAPQKQAGSVYQENAYYEQEFESQPKTKQEMLVPVKKKPWWARLGIQGRWAVFGLFAFILMVGVVWYFVWPRNPTLFFLEAGLADNTTANYSNTTMEATWSVNFTVNNMVNWVPTNIQNFDVSVIEVYSGEVFGKGSSGRLTLRPQSLDQIINVPISINLTRTASNPLLRTLLTSCWPEETSTPKESLNIKFSVVYYIVGIVWRTTSVFAPQSFFVCP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NIE9</accession>
    <name>A0A1C7NIE9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="9">RING finger protein ETP1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">A0J61_03631</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000160">
        <property type="protein sequence ID" value="OBZ88316.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NIE9"/>
    <dbReference type="STRING" id="101091.A0A1C7NIE9"/>
    <dbReference type="InParanoid" id="A0A1C7NIE9"/>
    <dbReference type="OrthoDB" id="163257at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016567">
        <property type="term" value="P:protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007265">
        <property type="term" value="P:Ras protein signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd16457">
        <property type="entry name" value="RING-H2_BRAP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011422">
        <property type="entry name" value="BRAP2/ETP1_RRM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047243">
        <property type="entry name" value="RING-H2_BRAP2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001607">
        <property type="entry name" value="Znf_UBP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24007">
        <property type="entry name" value="BRCA1-ASSOCIATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24007:SF7">
        <property type="entry name" value="BRCA1-ASSOCIATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07576">
        <property type="entry name" value="BRAP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02148">
        <property type="entry name" value="zf-UBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00290">
        <property type="entry name" value="ZnF_UBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50271">
        <property type="entry name" value="ZF_UBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="7">
        <location>
            <begin position="283"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="domain" description="UBP-type" evidence="8">
        <location>
            <begin position="317"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="46"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="529"/>
            <end position="584"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50271"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OBZ88316.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="651" mass="74604" checksum="C5016B9DF1976002" modified="2016-11-30" version="1">MYYYRLKCVLYSPEKIDLPDNFFGKLPTQVDTSAVKYLESYKHSTATKATTIPSSRRRSSQPAQQRHVPPTPIDTNKPHQNNSLEGQIDFRFGLIELSTIDMIPSQNSKKKRQMHETSLSLGYGVIHLYRDSNHVPEQDLPDTKIAEENSLDKPKDDTDDGKVICILAVPSYLTQKDFIQFLGNTNANILHYRFISDYSPNKYTVLLRFKDRASAFACYQKFNGRRFNMTEPEISHAVYIRSNTIETITIASNAYPYLNETLNKDLQSSLVQQQQEEAELPTCPVCLERLDQSISGLQSIQCHHTNRCDCISKWGKSDCPVCLCSYKPVLVSSSVNEHQRQQTPMNCKCFECGFTESLWICMVCGHIGCGRYQEAHAYDHYMETGHLYTLEIETQRIWDYLGDCYVHRLIQNTVDGALVELPPKSPPTDQKIDSVQYYQNNSQNNDTTMQKLDMRRDYFRQSAIGSSKTTGTTVATASPSMDDMRMHNLTQGDVPDNIAGGKLDAMSVEYSYMLTSQLDSQRMYYEEQIDAILHDIKNLTEQAKSIQDEVEGAKAQRITLIQTGEQLDSEIIELSKEKEKADKRTISFKDKYSAMEKNLNEERLLTKSLMRNNELLKKEAHEKEATFNTLTKQVKDLMQILETKEDVENKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NIH2</accession>
    <name>A0A1C7NIH2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Synaptotagmin-5</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">SYT5_1</name>
        <name evidence="4" type="ORF">A0J61_04804</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000243">
        <property type="protein sequence ID" value="OBZ87144.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NIH2"/>
    <dbReference type="STRING" id="101091.A0A1C7NIH2"/>
    <dbReference type="InParanoid" id="A0A1C7NIH2"/>
    <dbReference type="OrthoDB" id="270970at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00030">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.150">
        <property type="entry name" value="C2 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000008">
        <property type="entry name" value="C2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035892">
        <property type="entry name" value="C2_domain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45911">
        <property type="entry name" value="C2 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45911:SF4">
        <property type="entry name" value="MULTIPLE C2 AND TRANSMEMBRANE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00168">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00360">
        <property type="entry name" value="C2DOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00239">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49562">
        <property type="entry name" value="C2 domain (Calcium/lipid-binding domain, CaLB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50004">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0106">Calcium</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="C2" evidence="3">
        <location>
            <begin position="1"/>
            <end position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OBZ87144.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="133" mass="14947" checksum="DEA86838EB8D2601" modified="2016-11-30" version="1">MLSSHSAPRGLLTVNVIEARNLHKEDLGGHNDPYVELWLDEDYKQRSDEVKNTENPVWNQTFTFNIEEGSSKHKLYLKVLDKDIAGHDKIGEAKLDVAPAFKGELIDTWVKLPAMLGLSSHGEVHVSAEFVPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NIM7</accession>
    <name>A0A1C7NIM7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Cytochrome b-c1 complex subunit 10</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_02970</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000120">
        <property type="protein sequence ID" value="OBZ88987.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NIM7"/>
    <dbReference type="FunCoup" id="A0A1C7NIM7">
        <property type="interactions" value="57"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NIM7"/>
    <dbReference type="InParanoid" id="A0A1C7NIM7"/>
    <dbReference type="OrthoDB" id="2391627at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006122">
        <property type="term" value="P:mitochondrial electron transport, ubiquinol to cytochrome c"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019182">
        <property type="entry name" value="Cytochrome_b-c1_su10_fun"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28254">
        <property type="entry name" value="CYTOCHROME B-C1 COMPLEX SUBUNIT 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28254:SF1">
        <property type="entry name" value="CYTOCHROME B-C1 COMPLEX SUBUNIT 10, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09796">
        <property type="entry name" value="QCR10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="27"/>
            <end position="48"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ88987.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="71" mass="7562" checksum="6230602D93A2E7F7" modified="2016-11-30" version="1">MPVSKIVTSPHFSFITPEKFARVAPNLATWGVAAGSAVLLLGSDVPLLKKDILSKIPVVGSYWAVPEADQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NJB1</accession>
    <name>A0A1C7NJB1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">CTD kinase subunit gamma</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">ctk3</name>
        <name evidence="2" type="ORF">A0J61_03383</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000144">
        <property type="protein sequence ID" value="OBZ88566.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NJB1"/>
    <dbReference type="STRING" id="101091.A0A1C7NJB1"/>
    <dbReference type="InParanoid" id="A0A1C7NJB1"/>
    <dbReference type="OrthoDB" id="21266at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070692">
        <property type="term" value="C:CTDK-1 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032786">
        <property type="term" value="P:positive regulation of DNA-templated transcription, elongation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045943">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase I"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006569">
        <property type="entry name" value="CID_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042326">
        <property type="entry name" value="Ctk3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024637">
        <property type="entry name" value="Ctk3_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024638">
        <property type="entry name" value="Ctk3_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008942">
        <property type="entry name" value="ENTH_VHS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28291">
        <property type="entry name" value="CTD KINASE SUBUNIT GAMMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28291:SF1">
        <property type="entry name" value="CTD KINASE SUBUNIT GAMMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12243">
        <property type="entry name" value="CTK3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12350">
        <property type="entry name" value="CTK3_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00582">
        <property type="entry name" value="RPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51391">
        <property type="entry name" value="CID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="CID" evidence="1">
        <location>
            <begin position="6"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51391"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ88566.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="236" mass="27563" checksum="E4CF329F2BD45E33" modified="2016-11-30" version="1">MSAESDPFECRLEFIELLKKVNASQQSIHKAAIYAMRHRKLSEDLYSCLVEELEQATLNARLNMIYVLDAIFSASQKSKFTGYIDLTRPDLPRIIHAVVANGPKGVVNIPNTQKIISNWKRKQYFEADILEEAERPLIECASNLNPEQCATEESESMSKDDILRRMEEDRERHKRSREEIWIRPPDESKDAEFEEIWDSIDVLDPEYDYESMMVQNMLRLPTYAWHTMLSQRSNTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NK46</accession>
    <name>A0A1C7NK46_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_02422</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000091">
        <property type="protein sequence ID" value="OBZ89522.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NK46"/>
    <dbReference type="STRING" id="101091.A0A1C7NK46"/>
    <dbReference type="InParanoid" id="A0A1C7NK46"/>
    <dbReference type="OrthoDB" id="2266750at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ89522.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="518" mass="60286" checksum="D338E727C1BA5B12" modified="2016-11-30" version="1">MIRIQRLVAYILSLVLFLLITITLLPHLENNTSQVITTSPKKYNPHQERYLSWFPHSGFPEQHECFRNAIRLALETKRTIIAPMLRVNQYYPWLPFEELAKRYEAQEKTTLQLQCQTNQKNWQTELEPCETMNDWTEIPWSRIMDLEKIKKEYGVRIIERTQGHGWGIHESALNEPIEPEDVAIVDVMTFKENGTDWEHPDPYQKTSWSSWFQSHFQEKLKEPLKFVLETERLNAIDAKIIQFGALSSAARYPTTITQKSQELRKAMMKNRFNVPDQLPALTAESTKIVEALGGRFQYSTLIFNLSQLVTMDARAGTLQRLAMDGKVLTKEQEDKLVAQGPHEMEDLSEKARRELMEAVTLEIFGDIPINQAVSAAMPIRPNTPLSDLLKSDSFSNTNSKDRRRLLEACVNYHKQVEQRYPIYYLVSDMDVAPETRPDIFGPLLEMFPCVFSKLDMLEWGIQSKQWSVNQPDLLNDPHLNYEKLFQPFLDILIAGKGYSFFEIPNTHLTRFLNWSPKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NKR9</accession>
    <name>A0A1C7NKR9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Branched-chain-amino-acid aminotransferase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_02237</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000081">
        <property type="protein sequence ID" value="OBZ89721.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NKR9"/>
    <dbReference type="InParanoid" id="A0A1C7NKR9"/>
    <dbReference type="OrthoDB" id="59470at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.10.10">
        <property type="entry name" value="D-amino Acid Aminotransferase, subunit A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001544">
        <property type="entry name" value="Aminotrans_IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036038">
        <property type="entry name" value="Aminotransferase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043132">
        <property type="entry name" value="BCAT-like_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47703">
        <property type="entry name" value="D-AMINOACID AMINOTRANSFERASE-LIKE PLP-DEPENDENT ENZYMES SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47703:SF2">
        <property type="entry name" value="D-AMINOACID AMINOTRANSFERASE-LIKE PLP-DEPENDENT ENZYMES SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01063">
        <property type="entry name" value="Aminotran_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56752">
        <property type="entry name" value="D-aminoacid aminotransferase-like PLP-dependent enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ89721.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="314" mass="35932" checksum="8E2A82EBFD9313FD" modified="2016-11-30" version="1">MPKYTSLIIEQVNTKESDVNKAQYEIVPGDKTFNDFILSYPSGAYTGMRTVGRDAIVEFKLHTQRMINSIAHMKFEGNTTEETERARVALSAFRDPIQFEQRLRPLLKKGLEAYYERVDETTHTEHPHEAKVSVKQQPCFAAHFCHLKSFPPGIRVKVEIERKERKSPEVKDSQWVRERQSLEKNKPKDANEVILMDDSDQLYEGMASNFLVVKDGTVYCASLDHILMGSILKIVIGLCEKHQIPFKWEFPTLQDAKQGNWEGCCVTSTSRLLLPIEAIYVDTETIKFPQPSPVLELLREQVALEMANTASKIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NKW0</accession>
    <name>A0A1C7NKW0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Arp2/3 complex 34 kDa subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">arc2</name>
        <name evidence="7" type="ORF">A0J61_02187</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Component of the Arp2/3 complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Cytoplasm</location>
            <location evidence="1 6">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the ARPC2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000079">
        <property type="protein sequence ID" value="OBZ89761.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NKW0"/>
    <dbReference type="FunCoup" id="A0A1C7NKW0">
        <property type="interactions" value="383"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NKW0"/>
    <dbReference type="InParanoid" id="A0A1C7NKW0"/>
    <dbReference type="OrthoDB" id="148331at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005885">
        <property type="term" value="C:Arp2/3 protein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051015">
        <property type="term" value="F:actin filament binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005200">
        <property type="term" value="F:structural constituent of cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030041">
        <property type="term" value="P:actin filament polymerization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034314">
        <property type="term" value="P:Arp2/3 complex-mediated actin nucleation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1460.20:FF:000003">
        <property type="entry name" value="Arp2/3 complex 34 kDa subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1460.20:FF:000005">
        <property type="entry name" value="Arp2/3 complex 34 kDa subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1460.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007188">
        <property type="entry name" value="ARPC2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034666">
        <property type="entry name" value="ARPC2/4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12058:SF0">
        <property type="entry name" value="ACTIN-RELATED PROTEIN 2_3 COMPLEX SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12058">
        <property type="entry name" value="ARP2/3 COMPLEX 34 KDA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04045">
        <property type="entry name" value="P34-Arc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69645">
        <property type="entry name" value="Arp2/3 complex subunits"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0009">Actin-binding</keyword>
    <keyword evidence="3 6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 6" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU364015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OBZ89761.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="310" mass="36055" checksum="7683BB1818EF0075" modified="2016-11-30" version="1">MILLDYHNVIIKNTLESALKEQKLDALDMTVADFDGVTYHISTPESKSVIQISLGWACSHELFSFGAREILRREYGDLLLETPEQGYDVTLAVDAEKAPTEPEAVDDLIKKISLLKRNLLAAPFERAFTEQEECEKEQKTECNTALMAVHYREEEAIYVKSNFDRITVIFSTTFKDETDKIFGRVFLQEFVDARRRVPALQNAPQVLYSTREPPMELRHLNLKDSEHVSYVTFVLFPNHFTKGEVREETIGRIQIFRDYLHYHIKCSKAYMHTRMRARVRDFLKVLNRAKPEVQNVEKKTASGRTFVRRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NKZ3</accession>
    <name>A0A1C7NKZ3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="8">snRNA-activating protein complex subunit 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">Snapc3</name>
        <name evidence="8" type="ORF">A0J61_02268</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SNAPC3/SRD2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000083">
        <property type="protein sequence ID" value="OBZ89668.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NKZ3"/>
    <dbReference type="STRING" id="101091.A0A1C7NKZ3"/>
    <dbReference type="InParanoid" id="A0A1C7NKZ3"/>
    <dbReference type="OrthoDB" id="3437960at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019185">
        <property type="term" value="C:snRNA-activating protein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003681">
        <property type="term" value="F:bent DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001046">
        <property type="term" value="F:core promoter sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001006">
        <property type="term" value="F:RNA polymerase III type 3 promoter sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042795">
        <property type="term" value="P:snRNA transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042796">
        <property type="term" value="P:snRNA transcription by RNA polymerase III"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022042">
        <property type="entry name" value="snRNA-activating_su3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13421">
        <property type="entry name" value="SNRNA-ACTIVATING PROTEIN COMPLEX SUBUNIT 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13421:SF16">
        <property type="entry name" value="SNRNA-ACTIVATING PROTEIN COMPLEX SUBUNIT 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12251">
        <property type="entry name" value="SNAPC3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="487"/>
            <end position="506"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="492"/>
            <end position="506"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010410"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OBZ89668.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="506" mass="58160" checksum="3E33FAA994AD42A4" modified="2016-11-30" version="1">MSIIKPDNLKDEFNQLFEKHKEIESNPKFKALKEKYSHLNNFEPKHDLNTLSEIFQDPDLVARISFEAHEIMRVGCVRPSRVRSQPDIIISKKPQAKDVYRQALIDEDTANLYQSAEKTIDSDAQYVNPITPKQRIYLAQEKESVNATQLQPQQPHLASSSSSVIPAPQFTPDDAVFSVAQEAIASLTQKTPRMPLISSNEKPTETSDELERMFEQVANEISQSPLQTVRSKHLYNFLPRQSDLIAYNYVKEDFNPNESNQKKSRDKAKETLVTLIIHKASSPSVKSQEIECLGSQSLTDVRDAIFCLSDFEWHQTRMNAECADTASQENKINGACMIYLDHVFYLDTRYPNHPSYETWIDHWLTKKKVDRQKFHYTTALMQETILGQMKLKLNTPIALIHQEQCEHMLLIPDIRLLADNEYKSIDEFPRTTHNFTYIRFKCSMCSVYPATKLTHDDIISGFSPCYFCDICFDSFHQNDGVKPVAYHGQPGGQQSPFHQISANKKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NLL9</accession>
    <name>A0A1C7NLL9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Mitotic spindle checkpoint component mad3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">mad3</name>
        <name evidence="3" type="ORF">A0J61_03754</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000168">
        <property type="protein sequence ID" value="OBZ88204.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NLL9"/>
    <dbReference type="InParanoid" id="A0A1C7NLL9"/>
    <dbReference type="OrthoDB" id="248495at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032991">
        <property type="term" value="C:protein-containing complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004672">
        <property type="term" value="F:protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051754">
        <property type="term" value="P:meiotic sister chromatid cohesion, centromeric"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007094">
        <property type="term" value="P:mitotic spindle assembly checkpoint signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.430:FF:000003">
        <property type="entry name" value="Checkpoint serine/threonine-protein kinase BUB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.430">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015661">
        <property type="entry name" value="Bub1/Mad3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013212">
        <property type="entry name" value="Mad3/Bub1_I"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14030:SF4">
        <property type="entry name" value="BUB1 KINASE, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14030">
        <property type="entry name" value="MITOTIC CHECKPOINT SERINE/THREONINE-PROTEIN KINASE BUB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08311">
        <property type="entry name" value="Mad3_BUB1_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00777">
        <property type="entry name" value="Mad3_BUB1_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51489">
        <property type="entry name" value="BUB1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BUB1 N-terminal" evidence="2">
        <location>
            <begin position="70"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="207"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="290"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="346"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="207"/>
            <end position="226"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51489"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ88204.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="505" mass="59720" checksum="CC44D496FF5C3287" modified="2016-11-30" version="1">MNSEDDHLQSTEEERRQFLLSLIPEVGEVTRSKENVEPRVKGRSIRSLTTLLESDPSDREEEHVRVRTQFEQRLKSLDELDDPLQIYLDYLDWLLEYYSQQHTQITDVLKQATDQFKQDSRYQFDPRYLKVWIAYAKRIHEPREVYLFLMQQDIGQSLALFYEAYADHEESCKKYEEAAEIYQLGLHKNAMPKKRLERNYHLFQARRREREHRGLSRPSESKRQMETLRQTGQRTMLGHKFDSRSRVSVSANVYAGIEASHMSSRSHXSMFIESPSSESNGGGFAVYREKSTERTSPISPRLHITPHASSRQENKRAVDRYTGTIIPQNISSSPTPVTRFEIYQDSDNEEVETLSRPSITSKRPRLGLQEQATDRLKRKKKERETRFMQQKDRYMKSNNSRGDTEYIMHIKFKDDMCVQEARAYHYQLIPKPIVKQDAFSRYCQENRLQKAAPEYTAETLAAMESIGQLFQQSRHNNEEEEEDLTWTNPYQHFTPIERKHVNENE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NM09</accession>
    <name>A0A1C7NM09_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Nuc-1 negative regulatory protein preg</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">preg</name>
        <name evidence="2" type="ORF">A0J61_01815</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000062">
        <property type="protein sequence ID" value="OBZ90127.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NM09"/>
    <dbReference type="STRING" id="101091.A0A1C7NM09"/>
    <dbReference type="InParanoid" id="A0A1C7NM09"/>
    <dbReference type="OrthoDB" id="337735at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000307">
        <property type="term" value="C:cyclin-dependent protein kinase holoenzyme complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016538">
        <property type="term" value="F:cyclin-dependent protein serine/threonine kinase regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019901">
        <property type="term" value="F:protein kinase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd20558">
        <property type="entry name" value="CYCLIN_ScPCL7-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.10">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036915">
        <property type="entry name" value="Cyclin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013922">
        <property type="entry name" value="Cyclin_PHO80-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15615">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15615:SF117">
        <property type="entry name" value="PHO85 CYCLIN PHO80"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08613">
        <property type="entry name" value="Cyclin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47954">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="190"/>
            <end position="214"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ90127.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="245" mass="28011" checksum="4EDA8A031CDCF471" modified="2016-11-30" version="1">MNDTAETPEASNIVKVPEYFYAADINYLTHMIADMLGRLIAHNDLIPLTSSNLTRFHSRVPPNISLSDYLRRIVKYTSVEKSCLLILLIYIDRVCELHPQFTISSLTVHRFLITAVTVSSKALCDSYCTNSHYAKVGGISTQEINALELEFLSLIDWHLASTGPVLQQYYANLVEQHPCYERIVSEEMEGNKKRRRRSSATVDHNPVKKKDRKNSLNTELFEIEEEATKTHFDTLLDDETIPYIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NN78</accession>
    <name>A0A1C7NN78_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">40S ribosomal protein S15</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">RPS15_2</name>
        <name evidence="4" type="ORF">A0J61_03220</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uS19 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000135">
        <property type="protein sequence ID" value="OBZ88724.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NN78"/>
    <dbReference type="STRING" id="101091.A0A1C7NN78"/>
    <dbReference type="InParanoid" id="A0A1C7NN78"/>
    <dbReference type="OrthoDB" id="10258210at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022627">
        <property type="term" value="C:cytosolic small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000028">
        <property type="term" value="P:ribosomal small subunit assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.860.10">
        <property type="entry name" value="30s Ribosomal Protein S19, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002222">
        <property type="entry name" value="Ribosomal_uS19"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023575">
        <property type="entry name" value="Ribosomal_uS19_SF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11880">
        <property type="entry name" value="RIBOSOMAL PROTEIN S19P FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11880:SF2">
        <property type="entry name" value="SMALL RIBOSOMAL SUBUNIT PROTEIN US19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4" id="KW-0689">Ribosomal protein</keyword>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OBZ88724.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="67" mass="7946" checksum="D1198B9F3528E888" modified="2016-11-30" version="1" fragment="single">MHSSFSVGAWCQHSDALSADEQTPRKRTFRKFTYRGIDLEQLLDLSSEQFMDLVHCRARRRFQRGLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NP04</accession>
    <name>A0A1C7NP04_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Ubiquitin fusion degradation protein 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">ufd1</name>
        <name evidence="7" type="ORF">A0J61_01244</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UFD1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000037">
        <property type="protein sequence ID" value="OBZ90700.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NP04"/>
    <dbReference type="STRING" id="101091.A0A1C7NP04"/>
    <dbReference type="InParanoid" id="A0A1C7NP04"/>
    <dbReference type="OrthoDB" id="422728at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034098">
        <property type="term" value="C:VCP-NPL4-UFD1 AAA ATPase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031593">
        <property type="term" value="F:polyubiquitin modification-dependent protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036503">
        <property type="term" value="P:ERAD pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006511">
        <property type="term" value="P:ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.40.50:FF:000001">
        <property type="entry name" value="Ubiquitin fusion degradation protein 1 homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.330.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.40.50">
        <property type="entry name" value="Ubiquitin fusion degradation protein UFD1, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004854">
        <property type="entry name" value="Ufd1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042299">
        <property type="entry name" value="Ufd1-like_Nn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055417">
        <property type="entry name" value="UFD1_N1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055418">
        <property type="entry name" value="UFD1_N2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12555">
        <property type="entry name" value="UBIQUITIN FUSION DEGRADATON PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12555:SF13">
        <property type="entry name" value="UBIQUITIN RECOGNITION FACTOR IN ER-ASSOCIATED DEGRADATION PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03152">
        <property type="entry name" value="UFD1_N1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24842">
        <property type="entry name" value="UFD1_N2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="Ubiquitin fusion degradation protein UFD1 N-terminal subdomain 1" evidence="5">
        <location>
            <begin position="33"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="domain" description="Ubiquitin fusion degradation protein UFD1 N-terminal subdomain 2" evidence="6">
        <location>
            <begin position="134"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="243"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="298"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="311"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="324"/>
            <end position="333"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00074895"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF03152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF24842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OBZ90700.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="708" mass="80664" checksum="739931B4A6C87A81" modified="2016-11-30" version="1">MFNDYQDDDGFPTSFFGGMRPTLGGFMNPNRGFSENYRCFPIAMMRNGDEREGVNYGGKIILPQSALEKLSQLNISYPMLFKLIHGAEKKHSHAGVLEFIAEEGRVYLPQWMMETLGTEPGSIIEVKNVTLPLGSFVKIQPQSTDFLDITDHRAVLEKALRNFSTLTVGDVIQINYNNKIYEIKVLEVKPNQQDHMGISIVETDLEVDFAPPVGYTEPTSAKPAQMMKSKMAIDLPEPVNTSFIPFSGGGQSLRGKNRPVDNNAPMTESGNEEDDGPMSLPFGQLYFGFPVIPPPSKDGAEQEQKGKAFTEDEDEEDEWEREASSSTVTQNTRALPPNAYAVQTDILDKQDNLINATRQELTDQLTMLKHRLVQFEKEEALQKTLTEETKDQYMKALELTLDMLHVEEPIQDSFLDKNRLLSDTVTAQLDHWQRLFQDNQDKEDDLSWQKAYKTTEFDLIDLNAQIQGYQARLRQLTSDEAKINNLPKVLAILQSETEQYAKEMQYTSKQLEQFEKDSIRPCLKQLIETETASRQQKAIEQELTRIECLLKEMQQLYVVVTKQRACQQLALYLDNMASNNGLQLGILKAIEKELEVPTLPPCLDEDDNPSLLSDIQQLLGQQDPIEQTKTLRQQEKDLKQAWMDQMASYMTTAQALNEAKQRLSDSLFAYSNSKDSLVMTPKSYTNLQHEFEFRTHELKVALSELKKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NPT6</accession>
    <name>A0A1C7NPT6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Putative AC transposase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">TRA1_1</name>
        <name evidence="6" type="ORF">A0J61_01519</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000049">
        <property type="protein sequence ID" value="OBZ90446.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NPT6"/>
    <dbReference type="STRING" id="101091.A0A1C7NPT6"/>
    <dbReference type="InParanoid" id="A0A1C7NPT6"/>
    <dbReference type="OrthoDB" id="2288540at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052035">
        <property type="entry name" value="ZnF_BED_domain_contain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46481:SF10">
        <property type="entry name" value="ZINC FINGER BED DOMAIN-CONTAINING PROTEIN 39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46481">
        <property type="entry name" value="ZINC FINGER BED DOMAIN-CONTAINING PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3" id="KW-0863">Zinc-finger</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OBZ90446.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="376" mass="42720" checksum="8C6AFB29F8F13692" modified="2016-11-30" version="1">MSSQSFQKAIQDQVTCFSSIGFFVSRLRREASAFNINERSDAAKPPSIAHAAMEIIVQNNLPFTIVNAPELQQLMTMAFRAPNEATIQLPSANTIREKALGEFDALFPAITEWLSKQEKISLTIDTWSSSVKNGASDYMGVVAHFIDEDWKPKTLLIGFEPLEQRHTAPYLFEVFWSVFDKFQIKHKLFCITSENATIRFSKKENRLPCFGHVINLAVRELLDEGLIADVPRDNSNIYEMDILYSGDIGSDLGQNPVVKLRRGISYIYSGPRNSTFALIERAIQQFDAYNATCRNADTREIIRRYELSAAEKKCLVVVLSILKPFSRTTTWISSSRHATTNRSTSCYIELLMKLKIKNLLLKGLKPAIQIWLSFVW</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NPZ8</accession>
    <name>A0A1C7NPZ8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Sister chromatid cohesion protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">rad9</name>
        <name evidence="9" type="ORF">A0J61_00820</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the SCC2/Nipped-B family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000021">
        <property type="protein sequence ID" value="OBZ91118.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="FunCoup" id="A0A1C7NPZ8">
        <property type="interactions" value="185"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NPZ8"/>
    <dbReference type="InParanoid" id="A0A1C7NPZ8"/>
    <dbReference type="OrthoDB" id="418242at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090694">
        <property type="term" value="C:Scc2-Scc4 cohesin loading complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003682">
        <property type="term" value="F:chromatin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061775">
        <property type="term" value="F:cohesin loader activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140588">
        <property type="term" value="P:chromatin looping"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034087">
        <property type="term" value="P:establishment of mitotic sister chromatid cohesion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071169">
        <property type="term" value="P:establishment of protein localization to chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010468">
        <property type="term" value="P:regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990414">
        <property type="term" value="P:replication-born double-strand break repair via sister chromatid exchange"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd23958">
        <property type="entry name" value="SCC2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026003">
        <property type="entry name" value="Cohesin_HEAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024986">
        <property type="entry name" value="Nipped-B_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033031">
        <property type="entry name" value="Scc2/Nipped-B"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21704:SF18">
        <property type="entry name" value="NIPPED-B-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21704">
        <property type="entry name" value="NIPPED-B-LIKE PROTEIN DELANGIN SCC2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12765">
        <property type="entry name" value="Cohesin_HEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12830">
        <property type="entry name" value="Nipped-B_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="4 6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Sister chromatid cohesion C-terminal" evidence="8">
        <location>
            <begin position="1513"/>
            <end position="1702"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="29"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="141"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="224"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="54"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="7">
        <location>
            <begin position="224"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="7">
        <location>
            <begin position="276"/>
            <end position="290"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009252"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU364107"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF12830"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OBZ91118.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="1837" mass="209367" checksum="1D3E7A914000893F" modified="2016-11-30" version="1">MVSLMITSSDDEDQVRPIRRARKLKRVIHHISSSSSSEDEDNVPLNQRKAIRQATEDKLKTLDTKESTESEEPIPLKKPLPTIATPKAQSPAKKQKINTLITEQFESSKRVFSLNQRTRNRSNEEYGLLSKSRLHHQALANQKTRESAAAQSNHAKQKSAIIPPPPPSPFNGFKRPMTPPVFSVQSEPKKLSQVPPDANEFKTPSITLPSSSSHVPTDGFKVPMGPPMSQPMSPPMSQPMSPPMSQPMSPPMSQPMSPPMSQPMGPPMSQSMGPPMSQPMSPPMSQPMSPPMSQSMGPPMSQPMSPPSSGASAASTDFFISRLSHYIKCICEDLDQYQKTKRKTKGSVLVFGDKDSDLPLLDFEVTRLFGDKVSQVIRRHQNLDSIDMDQFSKVIKLMENTVIYASDLDVIDYHEKHPEDTDTVYSMLEKISQAFETCSVLFEIITSCKLDKKFVSHELIVNCLHFIKNQLDYTIYLLLDQSDAEDSLSLTSSAYLLHQKIQSSSHKQSVSSMIPHLIRIFRRLLLYISTEALDDDVLVIFAYISMGPFFHDCLYPQQSVLLQQTKNNEEVKFNPYEQLKFYALDILKHLFSKYPKHRRWIFEEILTSLGSLTTMDGTRKYRLKDNQTIHVMSALFMQLVQCSASIDNLTSHKTWHKKWNIKYQKAVKSGDQDEIKLLDDKLLHRASAAWQQSTESATNSASYFLEFLMSKCKSRRTDAYSLQEYRTILEQTLQDILTVMNDPDWPVAELIIRVLSRVLIALLEGSSSDQYLRSLAIEWLGIIASKIKLGYKKLSGDDSSCTPEWIHDLNLKLPQRIDMKTELASLQLLNQCRKHVLDYAKTERATSSTIDFYLCNWGFIESIIWKKSNQGYEIKKPKASVDAKEANVPLEENEQVQDNTLIQASTVDDTHSLAMDEDEAIDIKWPKETNVLFSETCKHYWLSCIGVDNSLLSPGSPYAFPELTRSDYVLLNELLASRQTLYTSYDFILSEILICLEKDAVVYRTKSLRAIGKIASEVPEVLEDKRINRVVIQRIHDTSPSVRDAAIDVMSRYLNRLDTIPEQLYKIISARIMDTALNVRKRVIKLLSSLYFKFTDPQLKMSIASKIILRIGDNEVSISQLSLKTTQDLLFMPFKHIEKDGNDYLGYSFANSPKQRKRKIVELTSIIIGAVSKLDSSVAAQNAALSQIVQKTISEADEKTKAWYYNIFQWIVDSLFERMIALDEEDNMTEFNHSLITVYSFTKACPHLLRESHISMLQPYLSVADQKADWTRIQYILTIYRDVLPSIKHHNLQFIQSTEQVIMQLLSRCPLNIIPSGISCLCIIVDTISHRYNLLIRMLGSCITKLKHVRALITEGNMLTLSGLLCQHFEFDKRRKEKPAEMESLNLVYRGDIDILVFDTLKFFTSDYMDELSQDGIQMRLTALQGLGYFYASHPTFMISEESTLLMDTVFDQGTTSLKKQLMLVFQEFLMAEEKRIGKREKEAGTSLWTKQIDVDTLLGNTEEYAELGVNGSLMQRYLKKILDCALVGSEDLRYAAFEVVSSIVHQGLANPVLCMSAIVAAETSSDVTLRNKAYYLHQYAHDKYGSLLYIQMSEYLMASFEYQKQLMGESANVQGYTSRSGEADAKIEPLLGLTFSILKEKKKIKFDFLLSLIKPFDFDIKSTANEDVQLDYLKYLGENMMALDLATSDEVLHMVYVMDRILMTLGADLLSYVHFLKKQDIIRPVDFDDEISEEPDLDLMVAAKLCVAMCILIRVKILLVEVYDIPDDEIRQYKPNSSKKGRDITRDFESQQCIDWNDFYYYRKGRNMNKSAAMDACLKFEHLLMNDTTAGVAEDT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NQ16</accession>
    <name>A0A1C7NQ16_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">ABC-type xenobiotic transporter</fullName>
            <ecNumber evidence="3">7.6.2.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="primary">ABCB1_0</name>
        <name evidence="17" type="ORF">A0J61_02597</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ABC transporter superfamily. ABCB family. Multidrug resistance exporter (TC 3.A.1.201) subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="7.6.2.2" evidence="3"/>
    <dbReference type="EMBL" id="LUGH01000100">
        <property type="protein sequence ID" value="OBZ89344.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="FunCoup" id="A0A1C7NQ16">
        <property type="interactions" value="20"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NQ16"/>
    <dbReference type="InParanoid" id="A0A1C7NQ16"/>
    <dbReference type="OrthoDB" id="6500128at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015421">
        <property type="term" value="F:ABC-type oligopeptide transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008559">
        <property type="term" value="F:ABC-type xenobiotic transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090374">
        <property type="term" value="P:oligopeptide export from mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd18577">
        <property type="entry name" value="ABC_6TM_Pgp_ABCB1_D1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18578">
        <property type="entry name" value="ABC_6TM_Pgp_ABCB1_D2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03249">
        <property type="entry name" value="ABC_MTABC3_MDL1_MDL2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1560.10:FF:000018">
        <property type="entry name" value="ATP-binding cassette subfamily B member 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000302">
        <property type="entry name" value="ATP-binding cassette subfamily B member 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000479">
        <property type="entry name" value="Multidrug resistance protein 1A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="entry name" value="ABC transporter type 1, transmembrane domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039421">
        <property type="entry name" value="Type_1_exporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43394:SF16">
        <property type="entry name" value="ABC TRANSPORTER B FAMILY MEMBER 4-LIKE ISOFORM X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43394">
        <property type="entry name" value="ATP-DEPENDENT PERMEASE MDL1, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="ABC transporter transmembrane region"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="12" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="11 14" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0677">Repeat</keyword>
    <keyword evidence="9" id="KW-1278">Translocase</keyword>
    <keyword evidence="5 14" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10 14" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="38"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="85"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="161"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="186"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="265"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="299"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="723"/>
            <end position="752"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="772"/>
            <end position="792"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="854"/>
            <end position="884"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="16">
        <location>
            <begin position="41"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="15">
        <location>
            <begin position="363"/>
            <end position="600"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="16">
        <location>
            <begin position="725"/>
            <end position="1015"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="15">
        <location>
            <begin position="1051"/>
            <end position="1294"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="656"/>
            <end position="682"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="656"/>
            <end position="665"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="666"/>
            <end position="682"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007577"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="OBZ89344.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="1300" mass="143043" checksum="D30C419A964AEB7A" modified="2016-11-30" version="1">MFRKKPNDVSTNDDQKPKKKESVPMFKLFRFSTPFEKLLIFFAFICSAAGGALNPVSIIIYGSYISNLTGSLNDTDSLLSSTLPVIKTMTYIGTGVLVASYISNCLWIVTGERQARRIRAMYVHAVLRQDMSWYDVATEGSLNTRLATDTQLIQDGISEKFGQLVMLIAQFIAGFVVAFVNGWRLAVIMLAVTPLLLTAGGAMGFFITKYTKKSQDAYALAGSVAEQVFNSIRTVYAFSLQKRFSKRYEKQLDNACKTGIKRGMALGLGFSFFMFSLFCIYAIALWYGSKLVGDGVLTGPTVLVVFLAMIMGSTSLLQLPSNLSAVSTASGAAFKIFSAIDRVPDIDPDSDEGIKLQNLKGSIEFKNVMFKYPTRPNLTVLEDFSLTIQRGMTVAFVGSSGSGKSTTVQLLQRFYDPLSGSISIDGHDLKDINVKCLRQQIGVVSQEPVLFNATIRQNLLLGTNEQVTEEDLINACKEANCHMFISQLPQGYDTLVGEQGGMLSGGQKQRIAIARAILKNPSLLLLDEATSALDTQSERLVQHALDRATKDRTTIIVAHRLSTIINADLIVVLDHGKIVEKGKHNELLQLNGAYANLVQKQKIDTKKFEDANAAISKDGNNTDADTDALLQQEQIEIQQQSKDAKKDLEEIDSHTTLENSIERSQAEPQKAAQNEKTSSRHSSVTINAYDIKLKQQKQEKKAVKKQKAPVTKVLMQMRPEWKLIFTGVIGAAVAGSVFPIYSLLFAKVIAIISVPGGDLSPGPMQGTNLYSFLFFILGVCAFLGFAAQFLSFEIAGELYTKRLRADLFAAYMRQEIGFFDREENNAGALTSRLAVDARNVNEMVTKVWGDVTQLCVTLIVGLVIAFIYSWALTLIILILAPFIMAATGYESRVYRGFEDKTKKANSESGEVAGEAIREIRTVAGLNKQHYFEDRYFHATDYPHRLALRKAYFSSIGYALNRGITIYTSVVGFYAGVRLIINGNINFEQMFTAMTVIMTAAQTAGRSSVFASTFAKAKFSAIASFSVLERQPTIDPELEGLEPDMNSIHGDIAFEDIKFAYPARPDITIFNGKLNLRGKAGQTIALVGPSGCGKSTTIGMLQRWYDPMAGAVSLDGTNVKSYSLYNLRSHQALVGQEPVVFDLSIADNIRFGIDDEKKEVTQEQIEEACKAANIHQFIKGLPQGYDTRVGDKGSQLSGGQKQRIAIARALIRKPRVLLLDEATSALDSDSERIVQEALDNILQEGGRTTITIAHRLSTIQNADLICVIKDGRVIEQGTHWDLLAIDGVYSELVQEQSLSVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NQ30</accession>
    <name>A0A1C7NQ30_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Nitrogen assimilation transcription factor nit-4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">nit-4_4</name>
        <name evidence="11" type="ORF">A0J61_00934</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000025">
        <property type="protein sequence ID" value="OBZ91009.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NQ30"/>
    <dbReference type="InParanoid" id="A0A1C7NQ30"/>
    <dbReference type="OrthoDB" id="2406834at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051615">
        <property type="entry name" value="Transcr_Regulatory_Elem"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31313">
        <property type="entry name" value="TY1 ENHANCER ACTIVATOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31313:SF81">
        <property type="entry name" value="TY1 ENHANCER ACTIVATOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0804">Transcription</keyword>
    <keyword evidence="4" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="9">
        <location>
            <begin position="13"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="domain" description="Xylanolytic transcriptional activator regulatory" evidence="10">
        <location>
            <begin position="261"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="33"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="563"/>
            <end position="586"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="41"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="563"/>
            <end position="580"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00066"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM00906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="OBZ91009.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="726" mass="81866" checksum="660CAD59BD47B240" modified="2016-11-30" version="1">MAKATLELKYKRLKVGHACYVCRSKKIKCDGLRPSRGRTCESSSIPSESESQDSSTIIDEQLGASTESDDDSILFSRTPKNSTTDDISATSSIADDNWSIDTKKCTSDQCSADLFSTFNQSPLTNSIQWKDDPALPLKYSCPIEMPSSDIQLQMIELFFQKRYCTTPIIPKKLFYDQLNSKGPMITPLLLNAIYCDVSSFASASELPDVPKPTVFFNRAKRLIDDFLDKPRVSTIIALSLLSRYEPRPSKSKLMAAQNSRTWMYSGMAFRMCLELGLNIDTPESCGMLSEEEIELRRRVFWFCYCLDKQQSLGKERTWSLSSSVVKTQLPFVLSNDRHDQENKHVIDYFRQHIKLMTIGEQVLRLRVLHPATDNSLNSLFAEQAVQLKLEVMQWSTNSSSEIDHVIQKGTSESSIEDSEHLSLKAILRLSYCILLSKILECAPKNRSILMEQRVNASEIVQQVEILCNDYSKVTQFEQLVYALMTAVLVHDGFLNDSDFQIAQQSQHFQNRCSALLKKIQKHVSIPECVTVLHHISVRNQQIGHNNNATSTAAQAIDNDNLSDLLSSSPSTTHTQSLPSPEHTSSDQFISQSIYSSDLLNDEITFKQLNTMFAIPPPALPIWNEPTQCLDEYPLSTSPSDMISFSYPSAALASNNDCSQLPNYTYNNYQHHSNPSPLFIDPIVHMSPSVYPSQESAIPFVQSEQPLVYSLNSVPSQPLMPQFVYYP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-06-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NRD0</accession>
    <name>A0A1C7NRD0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_00279</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000006">
        <property type="protein sequence ID" value="OBZ91671.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NRD0"/>
    <dbReference type="InParanoid" id="A0A1C7NRD0"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ91671.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="85" mass="9455" checksum="B1D6B8C4A0DC12F8" modified="2016-11-30" version="1">MHDLEITEPKPSDFQFINAQGFYEDDEPRYLPVRLIKIPEGEAAKIVTDNVRVAISTVVETRRVIGYFEPLGLDGRPVGPAPTSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NRJ3</accession>
    <name>A0A1C7NRJ3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_00220</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000004">
        <property type="protein sequence ID" value="OBZ91742.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NRJ3"/>
    <dbReference type="FunCoup" id="A0A1C7NRJ3">
        <property type="interactions" value="74"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NRJ3"/>
    <dbReference type="InParanoid" id="A0A1C7NRJ3"/>
    <dbReference type="OrthoDB" id="1914839at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035091">
        <property type="term" value="F:phosphatidylinositol binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048264">
        <property type="term" value="P:determination of ventral identity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd24142">
        <property type="entry name" value="ACL4-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28654">
        <property type="entry name" value="AXIN INTERACTOR, DORSALIZATION-ASSOCIATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28654:SF1">
        <property type="entry name" value="AXIN INTERACTOR, DORSALIZATION-ASSOCIATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13432">
        <property type="entry name" value="TPR_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="313"/>
            <end position="335"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ91742.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="335" mass="38425" checksum="4EAF6FFDCB2AAA9F" modified="2016-11-30" version="1">MSANYTVEDLKPRILENIDKLEYPAAYAFCQRALELEPHNAELLEITGQVELELEQFELARKHLLESIQIAPESNYSKYMYLGQLSVEKEAIAAFQKGVDLMVIERNKLPVESEEAKLLGSKISSALCSMTEIYLTDCCFEPEAEQKCEEYLSQAQQVDADHAETYQLLASVRLSQQRNEEAIAALSRSMELWIHREIGDPMIPIYDTRLALVKLLLECGMFEQAFTVLENLQKENDEVVDLWYLYGWTYYCLGDDEERTQEERIGLWADARDCLETSVKLYNMLGSDDDAMFEHAKELIASINEIVPAQVDEPEEEIVGDEELDIESDEDAMEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-06-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NRN7</accession>
    <name>A0A1C7NRN7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_00140</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000003">
        <property type="protein sequence ID" value="OBZ91781.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NRN7"/>
    <dbReference type="InParanoid" id="A0A1C7NRN7"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ91781.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="69" mass="8041" checksum="FF2423405F1FFF1C" modified="2016-11-30" version="1">MDPDSQSYELTVVSEFFIVSSDSLGLFLRDSAGPLVAVDEYNEVLLEIFQPWLIELQLQHKKRFFFRGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NRP6</accession>
    <name>A0A1C7NRP6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">PHO85 cyclin-1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">PCL1_0</name>
        <name evidence="2" type="ORF">A0J61_00153</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000003">
        <property type="protein sequence ID" value="OBZ91801.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NRP6"/>
    <dbReference type="STRING" id="101091.A0A1C7NRP6"/>
    <dbReference type="InParanoid" id="A0A1C7NRP6"/>
    <dbReference type="OrthoDB" id="10250320at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000307">
        <property type="term" value="C:cyclin-dependent protein kinase holoenzyme complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016538">
        <property type="term" value="F:cyclin-dependent protein serine/threonine kinase regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019901">
        <property type="term" value="F:protein kinase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd20557">
        <property type="entry name" value="CYCLIN_ScPCL1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.10">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036915">
        <property type="entry name" value="Cyclin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006671">
        <property type="entry name" value="Cyclin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013922">
        <property type="entry name" value="Cyclin_PHO80-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15615">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15615:SF108">
        <property type="entry name" value="PROTEIN CNPPD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00134">
        <property type="entry name" value="Cyclin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47954">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cyclin N-terminal" evidence="1">
        <location>
            <begin position="41"/>
            <end position="146"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ91801.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="172" mass="19997" checksum="79F864C93D43B2A5" modified="2016-11-30" version="1">MMMINAAPPTTLTFKSSPEPLLSFMVHNVDDLIQCSKERKYYQHMLLPELPKFIKIVYQKCRLSPTVLVIGLIYLERLKKNLPEQAQGEYDTPYKLFLASMIVATKYIEDYKSHASSIYKIVSPLYSSKDLNEMERSFLGVLKFDLFVDISEMDRFVDQHQESLELELLSMA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-06-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NSM5</accession>
    <name>A0A1C7NSM5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_00244</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000005">
        <property type="protein sequence ID" value="OBZ91686.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NSM5"/>
    <dbReference type="InParanoid" id="A0A1C7NSM5"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ91686.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="66" mass="7705" checksum="7D138AD4CA104381" modified="2016-11-30" version="1">MLQQDNLILYATRLELIDSKGLGKCFYVQQTCSMPIFFELRNVSDYNDGCHVEPYSKQFEMKVMSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-06-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NT43</accession>
    <name>A0A1C7NT43_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_00015</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000001">
        <property type="protein sequence ID" value="OBZ91886.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NT43"/>
    <dbReference type="InParanoid" id="A0A1C7NT43"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ91886.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="141" mass="16187" checksum="8DD3C784B395E9C2" modified="2016-11-30" version="1">MNKTLALDLCYMKEEVFKIRRLLRKVAFDLLLSGRVELLLNLRRKSPTLVIGQESILGAEHEEVSSPEEIRMADVENCMPRPENAINMKKSTKCINRINMINVLMTMADQSPGITQAMIRQSRRVFPNMENTGYPELSFSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MTU5</accession>
    <name>A0A1C7MTU5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">OTU domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_11698</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01002363">
        <property type="protein sequence ID" value="OBZ80253.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MTU5"/>
    <dbReference type="STRING" id="101091.A0A1C7MTU5"/>
    <dbReference type="InParanoid" id="A0A1C7MTU5"/>
    <dbReference type="OrthoDB" id="2286663at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd22744">
        <property type="entry name" value="OTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ80253.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="235" mass="26750" checksum="41242946E14EE2F7" modified="2016-11-30" version="1">MGAKTSRKRAAPDVSYGKNDFVYDKSFKANKRARGSITQAISSVLSNAINRSDMVGCLDPKGDGNCGFRAVAILVDSNGTRYEDEDQYLCVRSKMLEALEKYKHLYSRHFPAFQLNRLEDTLRKGLKKTDIAGWFYEPDCAHLVAGTYNIPVCLYPSSEAEHPSINPALTFLPLNLPKAKSTPVAIHIQNSLNLHWYAIKLGVNQTNLPTVYHHYFNIDGKLEEYELYWNKWHQF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MUE8</accession>
    <name>A0A1C7MUE8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Myb-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_11842</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01002573">
        <property type="protein sequence ID" value="OBZ80109.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MUE8"/>
    <dbReference type="InParanoid" id="A0A1C7MUE8"/>
    <dbReference type="OrthoDB" id="2281363at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00167">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001005">
        <property type="entry name" value="SANT/Myb"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="118"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="124"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="137"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="164"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ80109.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="164" mass="19173" checksum="386D0228B438C99C" modified="2016-11-30" version="1" fragment="single">MNVSDLLNPLPSAPNRPLRSRCISTPVISSNSHQNRYNYYRQRQDELDMDQISNEDEDEEDLMHSHMIGKPRSRFSEYEDNVIRQGVAQRLTWGQISDLLPHRKRATCFNRYRTLQGIRKSRKSQQQQQQQSSESENTTSLSPPFHYSQQPYFYANSNLSSSSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MUM0</accession>
    <name>A0A1C7MUM0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Cell division control protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">CDC1</name>
        <name evidence="3" type="ORF">A0J61_11453</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01002047">
        <property type="protein sequence ID" value="OBZ80498.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MUM0"/>
    <dbReference type="FunCoup" id="A0A1C7MUM0">
        <property type="interactions" value="252"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7MUM0"/>
    <dbReference type="InParanoid" id="A0A1C7MUM0"/>
    <dbReference type="OrthoDB" id="5977743at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006506">
        <property type="term" value="P:GPI anchor biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033308">
        <property type="entry name" value="PGAP5/Cdc1/Ted1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13315">
        <property type="entry name" value="METALLO PHOSPHOESTERASE RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13315:SF4">
        <property type="entry name" value="METALLOPHOSPHOESTERASE, ISOFORM E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="Metallo-dependent phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="3" id="KW-0132">Cell division</keyword>
    <keyword evidence="1 2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="269"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="297"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ80498.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="297" mass="34694" checksum="52079CA4CBFC2930" modified="2016-11-30" version="1" fragment="single">MLIADPQMTDDKSYQRHPLIMFFTKFYSSLYMKRNYSHLMYQIQPKDVIIMGDLSDNGREWKDDTFYAKEVNRFHTIFPTSDKIHYMAGNHDIGFGQGVNRTKVEQFKQYFGPTSYTFEHHGYQFVIMDTISLSSSDPILSDRSILDQIPSHPRRLLFTHVPLFRTEDQHCGPNRQQSRLNWIVNQRGHQYQNLVSKELSDLILDKIKPLAVFSGDDHDYCKVVHRDHIPEITVPTFSMSQGVQFPGLVVLEMNPQHLSTHLCWLPNQITIFVQYGLLALFTLLCLLVYHHSRVVSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MVG9</accession>
    <name>A0A1C7MVG9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_11118</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001690">
        <property type="protein sequence ID" value="OBZ80833.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MVG9"/>
    <dbReference type="InParanoid" id="A0A1C7MVG9"/>
    <dbReference type="OrthoDB" id="2279471at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="171"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="172"/>
            <end position="195"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ80833.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="226" mass="25186" checksum="643C7696D8C93AA4" modified="2016-11-30" version="1">MWSPLIEKLFRRDGLRTKWGESMGEDTADKATGIKVDLRLVKDTLARRKKEASKANVEVAKFGASPMKITGDSSKLFVESKIVIDNLAKEEHKKINRIIVPSLQIVGNKITLFSVALEANGVYVAVREGSAFIPSHVSHTKEFKRVIKLLLKFKAATMDLMAFGLDGEDEYSSNSNSNNNNNSSNSNKSNSRNSNSNISWLRGTWVPPTGEKKRLPALPEQLFFCK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MWC9</accession>
    <name>A0A1C7MWC9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_10835</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001430">
        <property type="protein sequence ID" value="OBZ81117.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MWC9"/>
    <dbReference type="InParanoid" id="A0A1C7MWC9"/>
    <dbReference type="OrthoDB" id="2428500at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ81117.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="68" mass="7622" checksum="2EE071C4ACB3CDEC" modified="2016-11-30" version="1">MSSGVDMHDKDHYGFTYLVSETKPCATVELFWLKVKYGVKRKPLEAGGTLTPRIINACSELTRKDCQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MX20</accession>
    <name>A0A1C7MX20_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Vacuolar membrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_10583</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001249">
        <property type="protein sequence ID" value="OBZ81367.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MX20"/>
    <dbReference type="STRING" id="101091.A0A1C7MX20"/>
    <dbReference type="InParanoid" id="A0A1C7MX20"/>
    <dbReference type="OrthoDB" id="431202at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022127">
        <property type="entry name" value="STIMATE/YPL162C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31735">
        <property type="entry name" value="VACUOLAR MEMBRANE PROTEIN YPL162C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31735:SF1">
        <property type="entry name" value="VACUOLAR MEMBRANE PROTEIN YPL162C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12400">
        <property type="entry name" value="STIMATE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="37"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="77"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="108"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="166"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="207"/>
            <end position="228"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ81367.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="261" mass="29558" checksum="2B5A80C335BB8603" modified="2016-11-30" version="1">MSILLTDNLLKVGESMTRIACQSGDLPDDKGCKLLDSFAILVQIALVSSALITLFYKRSREHPQRPVVVWALDVSKQFTGAAVIHFLNLAISYIAGRPRDGGPHTNLCVWYFLNVAVDTTVGVAILWTWLHLINAALTQLGVKQLETGRYGSPPSRDMLKPWIKQTCVFVLAESLMKLCVYGMFRHLPFLFSLGEWALSWTDGNYRYQVIFVMLIFPLIMNIVQFWIVDTIVKVSPTKITITIDDTTDEHRPLLPKHHTRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MX42</accession>
    <name>A0A1C7MX42_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_10950</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001534">
        <property type="protein sequence ID" value="OBZ80999.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MX42"/>
    <dbReference type="InParanoid" id="A0A1C7MX42"/>
    <dbReference type="OrthoDB" id="10437850at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="50"/>
            <end position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ80999.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="76" mass="8769" checksum="B1349F793EE5C39B" modified="2016-11-30" version="1">MSDLVRQIGCPTGGVLRSTFDIPLVVVIDFANTEEIPVFLRNWNVNRKRKFKPNVNQKNSNKRQRRTGPETSENKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MX77</accession>
    <name>A0A1C7MX77_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">catalase</fullName>
            <ecNumber evidence="3">1.11.1.6</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">katE_2</name>
        <name evidence="11" type="ORF">A0J61_10446</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the catalase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.11.1.6" evidence="3"/>
    <dbReference type="EMBL" id="LUGH01001177">
        <property type="protein sequence ID" value="OBZ81505.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MX77"/>
    <dbReference type="STRING" id="101091.A0A1C7MX77"/>
    <dbReference type="InParanoid" id="A0A1C7MX77"/>
    <dbReference type="OrthoDB" id="6880011at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004096">
        <property type="term" value="F:catalase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042744">
        <property type="term" value="P:hydrogen peroxide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006979">
        <property type="term" value="P:response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03132">
        <property type="entry name" value="GATase1_catalase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1370.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.180.10">
        <property type="entry name" value="Catalase core domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018028">
        <property type="entry name" value="Catalase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024712">
        <property type="entry name" value="Catalase_clade2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043156">
        <property type="entry name" value="Catalase_clade2_helical"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011614">
        <property type="entry name" value="Catalase_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002226">
        <property type="entry name" value="Catalase_haem_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010582">
        <property type="entry name" value="Catalase_immune_responsive"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041399">
        <property type="entry name" value="Catalase_large_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020835">
        <property type="entry name" value="Catalase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42821">
        <property type="entry name" value="CATALASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42821:SF1">
        <property type="entry name" value="CATALASE-B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00199">
        <property type="entry name" value="Catalase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06628">
        <property type="entry name" value="Catalase-rel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18011">
        <property type="entry name" value="Catalase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00067">
        <property type="entry name" value="CATALASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM01060">
        <property type="entry name" value="Catalase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="Class I glutamine amidotransferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56634">
        <property type="entry name" value="Heme-dependent catalase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00437">
        <property type="entry name" value="CATALASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51402">
        <property type="entry name" value="CATALASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0349">Heme</keyword>
    <keyword evidence="9" id="KW-0376">Hydrogen peroxide</keyword>
    <keyword evidence="8" id="KW-0408">Iron</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Catalase core" evidence="10">
        <location>
            <begin position="1"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="11">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012314"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM01060"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="OBZ81505.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="489" mass="55476" checksum="E3B41634BCBB18A1" modified="2016-11-30" version="1" fragment="single">DGKSVFVKFVWKPLQGLSNLVWDEAQKIAGKDPDFHRRDMYEAIDRGDFPQYEFGVQIVPEEDQFKYPFDLLDASKIIPESLVPVTRLGKMTLNRNVDNFFSETEQVTFHMGHVVRGIGFTNDPLLHGRLFSYLDTQLNRMNSKNFMQLPINRPIVPVHNNFRDGFMQPVVFQGKVNYYPNTMQDNTPQVASPQTDGYIDYPEYVNGSKGRGKYGKFADHFSQAQLFYNSLTTPEQQQVVDAARFELGRCSNMTIRQNMVQVFNRVDNNMATRIAFGVGVPLPEQTEVNQNQTDHALSIENYPCPKDIKTKRVAILTVPGIDAQEAKTMFDILHRKGAYVDMIGLKQGEQQNGLWANHTYLTTSSVLYDGFYVPSGDVQAFYLLSNNISAFPYQEPLVYLLDAFRHGKPIAASGHGSLLLKASGIPLSVMTLSHEQQKNLGLFVVDGIADFDMFGDELEKGLRRQRYWNRLPLDPNAKQSPTLSQPCSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MXS8</accession>
    <name>A0A1C7MXS8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Transmembrane 9 superfamily member</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">TM9SF3</name>
        <name evidence="8" type="ORF">A0J61_10305</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the nonaspanin (TM9SF) (TC 9.A.2) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001111">
        <property type="protein sequence ID" value="OBZ81647.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MXS8"/>
    <dbReference type="STRING" id="101091.A0A1C7MXS8"/>
    <dbReference type="InParanoid" id="A0A1C7MXS8"/>
    <dbReference type="OrthoDB" id="1666796at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072657">
        <property type="term" value="P:protein localization to membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004240">
        <property type="entry name" value="EMP70"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10766:SF41">
        <property type="entry name" value="TRANSMEMBRANE 9 SUPERFAMILY MEMBER 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10766">
        <property type="entry name" value="TRANSMEMBRANE 9 SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02990">
        <property type="entry name" value="EMP70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0732">Signal</keyword>
    <keyword evidence="3 7 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008810975" description="Transmembrane 9 superfamily member" evidence="7">
        <location>
            <begin position="31"/>
            <end position="606"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="238"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="303"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="340"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="375"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="405"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="464"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="498"/>
            <end position="524"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="531"/>
            <end position="555"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="567"/>
            <end position="588"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005227"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU363079"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OBZ81647.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="606" mass="70055" checksum="B87EC3F3ECAE09DC" modified="2016-11-30" version="1">MKLFAWKEKNKHRLILLLWLTLFSLSTILADEHNHIYKEGDEVVVWMNTVGPLNNRQETYPYFQLPFCQGPHSLQHHHESLGEALQGMDLVQSGIPLQYKKDEANKVYCKRTLDAQEIDVLRYAVDNQYWYTMFVDNLPVSGIVGRDADEDKEESEREIDPHFKHLYVYTHKSFSIQYNQDRIISVSLQHANPVELGYNQPLELTFTYTVDWNPTDISFENRFESLLETDFFEHKVHWLSIFSSFMMVLFLTGLVSVILLRTVKRDFTRYDREEGLTDFDRDLGDEYGWKQVHGDVFRQPPRLMLMSALMGTGSQLVILAGVVILYTILGDLYAERATILTATIFLYALTSFVAGYTSARYYVRYGGKEWIKTVIMTASVWPGLVALIGGFINSLAIYYNSSRAISFYALLSVVALWLFLCFPLTLLGTIVGRNLVSANGNDFPCRVNPIPRPIPEKMWYAEPLMIVALGGILPFASIFIEIYFIFTSFWTYKIYYVYGFMLLVFIILLIVSACVSIVSTYFLLNSEDHRWHWVSFMTCASTAGYVYLYAVYYFMVKTKMTGMFQTSFYFGYSALLSLGMFFMLGFVGHTASSMFVRKIYQNVKID</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MY29</accession>
    <name>A0A1C7MY29_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="15">Sorting nexin-1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="15" type="primary">SNX1</name>
        <name evidence="15" type="ORF">A0J61_10176</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="3">Golgi apparatus</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
            <orientation evidence="1">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the sorting nexin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001060">
        <property type="protein sequence ID" value="OBZ81775.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7MY29"/>
    <dbReference type="InParanoid" id="A0A1C7MY29"/>
    <dbReference type="OrthoDB" id="271862at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005768">
        <property type="term" value="C:endosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030904">
        <property type="term" value="C:retromer complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035091">
        <property type="term" value="F:phosphatidylinositol binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045053">
        <property type="term" value="P:protein retention in Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042147">
        <property type="term" value="P:retrograde transport, endosome to Golgi"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd22453">
        <property type="entry name" value="KH-I_MUG60_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd06859">
        <property type="entry name" value="PX_SNX1_2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1520.10:FF:000013">
        <property type="entry name" value="Putative Sorting nexin 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1270.60:FF:000022">
        <property type="entry name" value="Sorting nexin 3 protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.60">
        <property type="entry name" value="Arfaptin homology (AH) domain/BAR domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1370.10">
        <property type="entry name" value="K Homology domain, type 1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1520.10">
        <property type="entry name" value="Phox-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027267">
        <property type="entry name" value="AH/BAR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004087">
        <property type="entry name" value="KH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004088">
        <property type="entry name" value="KH_dom_type_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036612">
        <property type="entry name" value="KH_dom_type_1_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056553">
        <property type="entry name" value="KH_Mug60-KHD4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001683">
        <property type="entry name" value="PX_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036871">
        <property type="entry name" value="PX_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015404">
        <property type="entry name" value="Vps5_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10555:SF170">
        <property type="entry name" value="FI18122P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10555">
        <property type="entry name" value="SORTING NEXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00013">
        <property type="entry name" value="KH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24563">
        <property type="entry name" value="KH_Mug60-KHD4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00787">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09325">
        <property type="entry name" value="Vps5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00322">
        <property type="entry name" value="KH"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00312">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103657">
        <property type="entry name" value="BAR/IMD domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54791">
        <property type="entry name" value="Eukaryotic type KH-domain (KH-domain type I)"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64268">
        <property type="entry name" value="PX domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50084">
        <property type="entry name" value="KH_TYPE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50195">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="10" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="8" id="KW-0653">Protein transport</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="domain" description="PX" evidence="14">
        <location>
            <begin position="1042"/>
            <end position="1159"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="801"/>
            <end position="829"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="955"/>
            <end position="1010"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="12">
        <location>
            <begin position="1201"/>
            <end position="1228"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="12">
        <location>
            <begin position="1319"/>
            <end position="1367"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="801"/>
            <end position="818"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="963"/>
            <end position="973"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="974"/>
            <end position="988"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="998"/>
            <end position="1008"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="15">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004287"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="OBZ81775.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="1412" mass="158667" checksum="7A064CEDD241A3E8" modified="2016-11-30" version="1" fragment="single">QSSFASQNTVSILITGIPDNAELARVQTLVMLDRLSELYVDTVAIPYKLHHLICGRKRTGLQSILEETATSIYFPSPFVFQKDDNYSPPIYITGQANDVMRVKEMLTKLASQKAQSMYHKDAVLHPRKLDWMLLHRRNDLRKVMRDNGSFLLFPKMGSGSNIVTVYAESRVNAERTLRSLHFLACSVYEACFYFNRDNVIYGMDNVHPIFNSMANITTLVSQLSQISGAEVSYRVDPGCIEAFGTERAIRNVYQRLHDMSFLKVFHQSTIFNVELSNDQREFISGKKSGKINKIMKTSGAKIKFLPFSEYNFIIEVESNNFNKALDGLTLLQEELPAEISFYVPEVYHKRIIGVGGKNIQRIMKKYGVYVKFSNAEEFAALGGYYDNDDNVVARTPMKNQVNLENLRHAVMDLINPKDRDCVEQVLYDIPFWLHRTLIHDQAAFLAEMTKKTNTHLIWPDNELASNYLTLVGPESQVGLAAQMVRSIVPEEYDVHLPFSTHLKSVLESASYKDIVQRIANEHSITVELKKKKQDDGNESDEVIAFKMTKGIIDRLNPALEILIGYFKSQQVNLYDDSAIVRHVNTAPSATNPFSSSSFPVFDSRILGPSLPSGNHLSNQSIQQSRLTKDLPLELVSPTASSSSSLLTDFPLPLSGMHNGLKSYSLFDYPCAVGGNPLDASWKSFREMNSSRTVDSLRAIFDSPEANKPLAPPPPSMPFVSPLSFRNGPPAAQSGLDIWSNPPQQVSLNGFVGSPPLSGLETKPHSMLYTIDQSNNTKTNGSFYPPLGQKPDFNNAYVVPTSSTSTGSNNSSMHSSQSMPDIVLDSSPKKSSNLPFQINNYMRTQTPPPPLIYPSNTATSGSNKPLSQSTAVQFALSPSISTPTLAGAAAAVNNKNNTTTASVQSSNPHVSSTTGLEKPLDFPALFSANHSSADETVIVQSLLNNMTIGAFGEDSLESNPFADTPSQSTHQFSEPTLTSPPTMTTATPTEVEQPESDSQRPSTPSQKDMSITKHLDDLHIETTIEQEDTQSESLRVPESGSRPFFEVSIEDPQKVGDAINAHIVYKVRTKTNSPSFRSSEFIVARRYRDFLWLYNQLTSGNPGVIVPPVPEKHALGRFQDDFVESRRIALERCLQKIVAHPMLYGDPDLKVFLESESFNVEKRQRRAEPENSKMSFMRSFSETLSNAATSPFSKFVEVDEWFESKKNQLDGLESQLRSLLKSVEELGMATSEFGESMFPLASAELNRNLSTHLMVLGEIQKQMKELHEQQAQYDIITLENTIDEYIRIIGSIRIAFHARVKAYQTYQQADSELQKKLAFFERLKAQQKNKTEKLNVHQQEINEMKDKVEELQQEFQHVSKLIKNELDRFDKEKVEDFRDSVEQFLRSMIEHQKQIIALWETYFEQTEGLSEEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MY92</accession>
    <name>A0A1C7MY92_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Putative pyrimidine permease RutG</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">rutG_0</name>
        <name evidence="8" type="ORF">A0J61_10582</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001248">
        <property type="protein sequence ID" value="OBZ81369.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MY92"/>
    <dbReference type="STRING" id="101091.A0A1C7MY92"/>
    <dbReference type="InParanoid" id="A0A1C7MY92"/>
    <dbReference type="OrthoDB" id="1641903at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042907">
        <property type="term" value="F:xanthine transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006043">
        <property type="entry name" value="NCS2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006042">
        <property type="entry name" value="Xan_ur_permease"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00801">
        <property type="entry name" value="ncs2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42810">
        <property type="entry name" value="PURINE PERMEASE C1399.01C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42810:SF2">
        <property type="entry name" value="PURINE PERMEASE C1399.01C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00860">
        <property type="entry name" value="Xan_ur_permease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="92"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="115"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="147"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="175"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="206"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="232"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="278"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="315"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="353"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="385"/>
            <end position="407"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008821"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OBZ81369.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="487" mass="52438" checksum="7A87326F804AD2FB" modified="2016-11-30" version="1">MEKHSHQFDPSRKDLAESFSNDSTDLSTGHKFFSKYTVLSYFPKYKLKTSGPIFIDERPPIFQCALMGIQHVLAMFGSTVLAPLMMGFDTNTALFFSGIGTIIFYICTGGRVPSYVGSSFGFIGVVVSATGYSYAPGAGRNPNTDVAAGGIIVCAVVYLAIGVVVHFAGYRWIEYVMPPVVTGTVVMTIGIHLSTSAFQSATETTLDGWMAFTTVMLISLVSIYAPGMLKRIPILIGMVIGYLIYFGVSWSGHGPAIDYTEVYEAAWFAAPSFVKPRFEGQAISIIVPVCVVLLAENLGHIKAVGAMAEKPLDKYLARAIIGDALATIVSASGGGPGTTTYSENIGVMAVTQIFSTLIFLVAAIIAILLGFVQKFGAAIHTIPEGVFGGLSIILFGLITVSGARIWVENEVDFKDSRNMLVAGVPVIIGAAMQSTLKWGNFQLDGIGLPTYSAILLYQILRGWDGIRDLFHRKKSVDEQHQDYDSSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MZ03</accession>
    <name>A0A1C7MZ03_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Coiled-coil domain-containing protein 130</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_09900</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CWC16 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000967">
        <property type="protein sequence ID" value="OBZ82053.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MZ03"/>
    <dbReference type="FunCoup" id="A0A1C7MZ03">
        <property type="interactions" value="386"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7MZ03"/>
    <dbReference type="InParanoid" id="A0A1C7MZ03"/>
    <dbReference type="OrthoDB" id="360327at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071014">
        <property type="term" value="C:post-mRNA release spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005684">
        <property type="term" value="C:U2-type spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007590">
        <property type="entry name" value="Saf4/Yju2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12111">
        <property type="entry name" value="SPLICING FACTOR YJU2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12111:SF2">
        <property type="entry name" value="SPLICING FACTOR YJU2B-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04502">
        <property type="entry name" value="Saf4_Yju2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="275"/>
            <end position="330"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005595"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ82053.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="330" mass="38332" checksum="E67631CA645B97D8" modified="2016-11-30" version="1">MQPFNKYYPPDWTPEKGSINTHYGKHALGDRARKLDQGILIVRFELPFNIWCTGCDNHVGQGVRYNAEKKKIGNYYSTPILQFRMRCHLCSNWIEIHTDPKNTQYVVVSGARKKVEEWDAEDTEVIKLQEPEIKEKLENDPMYRLEHGIADKKTITEAKPHLTQLQQLNTSQWADPYTRSQQLRKHFREEKKRDRVAKEETERVRDKHSLQIELLPPTIHDEVEAKSISYASTEQLDKERLKTAVSPLFQQKKEKSAVHHLSHIAKIHTRLKTDPFYSSNPFSRRKEQPVVNASKKLENMITKPTKKAKPNESDSIVSSLAAYGTDSDSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MZ85</accession>
    <name>A0A1C7MZ85_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="1">2.7.11.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Heme-regulated eukaryotic initiation factor eIF-2-alpha kinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="15" type="primary">hri2_1</name>
        <name evidence="15" type="ORF">A0J61_09811</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="9">Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. GCN2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="1"/>
    <dbReference type="EMBL" id="LUGH01000944">
        <property type="protein sequence ID" value="OBZ82137.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MZ85"/>
    <dbReference type="FunCoup" id="A0A1C7MZ85">
        <property type="interactions" value="94"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7MZ85"/>
    <dbReference type="InParanoid" id="A0A1C7MZ85"/>
    <dbReference type="OrthoDB" id="1405469at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004694">
        <property type="term" value="F:eukaryotic translation initiation factor 2alpha kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017148">
        <property type="term" value="P:negative regulation of translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd13996">
        <property type="entry name" value="STKc_EIF2AK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050339">
        <property type="entry name" value="CC_SR_Kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054521">
        <property type="entry name" value="HRI2_3H"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11042:SF187">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 2-ALPHA KINASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11042">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 2-ALPHA KINASE EIF2-ALPHA KINASE -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22949">
        <property type="entry name" value="HRI2_3H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="12" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="15" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="6 15" id="KW-0418">Kinase</keyword>
    <keyword evidence="5 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="15" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="8" id="KW-0652">Protein synthesis inhibitor</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="14">
        <location>
            <begin position="234"/>
            <end position="683"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="318"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="364"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="483"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="549"/>
            <end position="588"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="12">
        <location>
            <begin position="684"/>
            <end position="746"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="11"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="13">
        <location>
            <begin position="323"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="364"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="13">
        <location>
            <begin position="383"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="487"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="264"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00037982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00042914"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="OBZ82137.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="754" mass="85907" checksum="B0DCA292C91020A2" modified="2016-11-30" version="1">MSFQIHDDSSNELLESQKQSPHWLNPTVDSASYTPHKLTVLTTPLDENPPVFESATPDSTKRYQTKMLLASLIEHFCSAYGDTPDANRKVFFLICQTLRSLGMMDAEFMDEMTSVRSAFQQAFHKLFYTAVQTVRNQDLLEFDSPMPRLLVKDIASSPSSQSAMDYFSQKPCSVQSPSLSKSPLLQSPLAKSPLIQSPLQVSSLSSSSSSSVPEMQPNEFLNLNVQNSRYNTDFVELNLLGKGGFASAYRARNKLDGIDYAIKKIRLGNDIEAEEQKKSDDNPYERIFREIKNLARLEHQNVVRYYSSWLEFDESPIRSDEKNSEDDFEEDDYEDESDSVFHGRDPTFSDYSCDYSGMSQIQFGEGSTSNYDDNPTSSSYTNHRSRNRSRTRQQQKKSSGGWTLFIQMQLCPTTLHDYIRLRNKQYAQDTTSLDPLVETKRNLEIFYQILQGTAYIHEQGLIHRDLKPSNIFLYTTDKHKRHQPTVSACSSPPSSSSSVPSLSGISFSTVSDPVSDLEPTLHFWWEESWVPKIGDFGLAAEAMDDEGTGESVLVPTPISSTPPSPQIGPVSDHTSSRRRPKPVRTRTMGVGTRTYASPEQLAAQIYDEKVDIYSLGIILFELFQPFTTGMERADALDKLKRGIFPHGFPKLYPNVAVLILWMMNLDPQQRPSAEQLLEFESFTANQAQQQDLEIQTTLQQLERENRELRQQLDQAEQAKEEMRQRLEAMQLKLDAYEAKDKQTKKKKEVRWVFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MZG9</accession>
    <name>A0A1C7MZG9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_09812</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000944">
        <property type="protein sequence ID" value="OBZ82138.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MZG9"/>
    <dbReference type="InParanoid" id="A0A1C7MZG9"/>
    <dbReference type="OrthoDB" id="2408655at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="130"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="168"/>
            <end position="204"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ82138.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="204" mass="23163" checksum="59EDD7D7ACAFFA40" modified="2016-11-30" version="1">MNSTKKSKQRSTDPVSTDDLQHQYEKTKAMLNNPNLKLPDGGAKLKAKLAELEVLMKQSLTDKVSELSLNDHKVNIRQQTLERSKQTPMSTNLLRAHSAKDARVAQMMSLEESMKLQESQQKDIKLANMRKRMEEVTRSSKTQESLADDLEMAMNQLQLNPEIGQPSPDDDGSSEEEYDSDDSLEGAYEDEGFEEDTEEDERHS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MZQ4</accession>
    <name>A0A1C7MZQ4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_09576</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000882">
        <property type="protein sequence ID" value="OBZ82375.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MZQ4"/>
    <dbReference type="STRING" id="101091.A0A1C7MZQ4"/>
    <dbReference type="InParanoid" id="A0A1C7MZQ4"/>
    <dbReference type="OrthoDB" id="2271095at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="189"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="270"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="303"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="361"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="386"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="414"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="445"/>
            <end position="456"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ82375.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="481" mass="55503" checksum="680EEBCF454310CD" modified="2016-11-30" version="1">MPSQYAQRNRSAVRRALRTEIESVREKVRAAYILETRRKEGEKLTEEELAIIEERPVNLKLNEALEEMYLRRSSESVERNRALQEEEVWSLMHFFYLVRLAQQGFFSLISSINPAIEPQALIYLADKMVGHSLHASRSPDEQTRKANKAQFRNTVRNLHAEKEEPVAEGFRTTYKQVMQLIHGLVDQSLGEQSRNEKAAAQEQDDDNTSKANETTPSKQPPVPTIPPIWVVMPYSSMIDGATFAMPGAVPTLPYPSTLLPTHMLPRHAFPFMHNPLDEPKRRSNKKKSKKDKDTSMNTAPAEEEPKDHNKKTKEPVESTEESKESAEKAKEEPIEEVKEQTVTEAEQFEDNDYDDRFADPETSDEEVREEEEEDEEDDGELTMLQKEQDQVEETKEQEQKKETKEENGWDAVETDQQQQSSENGWGEVSQEEVAADSKWQSFAASREDREDHEEPNGRSNSSRNSPRKQNRSYMKNKNGRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MZW3</accession>
    <name>A0A1C7MZW3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">isopentenyl-diphosphate Delta-isomerase</fullName>
            <ecNumber evidence="4">5.3.3.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">idi1</name>
        <name evidence="14" type="ORF">A0J61_09636</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>isopentenyl diphosphate = dimethylallyl diphosphate</text>
            <dbReference type="Rhea" id="RHEA:23284"/>
            <dbReference type="ChEBI" id="CHEBI:57623"/>
            <dbReference type="ChEBI" id="CHEBI:128769"/>
            <dbReference type="EC" id="5.3.3.2"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="12">
            <dbReference type="Rhea" id="RHEA:23285"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Isoprenoid biosynthesis; dimethylallyl diphosphate biosynthesis; dimethylallyl diphosphate from isopentenyl diphosphate: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the IPP isomerase type 1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.3.3.2" evidence="4"/>
    <dbReference type="EMBL" id="LUGH01000896">
        <property type="protein sequence ID" value="OBZ82311.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MZW3"/>
    <dbReference type="FunCoup" id="A0A1C7MZW3">
        <property type="interactions" value="504"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7MZW3"/>
    <dbReference type="InParanoid" id="A0A1C7MZW3"/>
    <dbReference type="OrthoDB" id="510307at2759"/>
    <dbReference type="UniPathway" id="UPA00059">
        <property type="reaction ID" value="UER00104"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004452">
        <property type="term" value="F:isopentenyl-diphosphate delta-isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050992">
        <property type="term" value="P:dimethylallyl diphosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009240">
        <property type="term" value="P:isopentenyl diphosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006694">
        <property type="term" value="P:steroid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02885">
        <property type="entry name" value="NUDIX_IPP_Isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.79.10:FF:000012">
        <property type="entry name" value="Isopentenyl-diphosphate Delta-isomerase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.79.10">
        <property type="entry name" value="Nucleoside Triphosphate Pyrophosphohydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011876">
        <property type="entry name" value="IsopentenylPP_isomerase_typ1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015797">
        <property type="entry name" value="NUDIX_hydrolase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000086">
        <property type="entry name" value="NUDIX_hydrolase_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02150">
        <property type="entry name" value="IPP_isom_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10885">
        <property type="entry name" value="ISOPENTENYL-DIPHOSPHATE DELTA-ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10885:SF0">
        <property type="entry name" value="ISOPENTENYL-DIPHOSPHATE DELTA-ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00293">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF018427">
        <property type="entry name" value="Isopntndiph_ism"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55811">
        <property type="entry name" value="Nudix"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51462">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11 14" id="KW-0413">Isomerase</keyword>
    <keyword evidence="10" id="KW-0414">Isoprene biosynthesis</keyword>
    <keyword evidence="5" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="9" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="7" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0752">Steroid biosynthesis</keyword>
    <feature type="domain" description="Nudix hydrolase" evidence="13">
        <location>
            <begin position="48"/>
            <end position="195"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004826"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007579"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012057"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022955"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00029294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="OBZ82311.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="226" mass="26437" checksum="E58CBD692FC1E391" modified="2016-11-30" version="1">MAPDLKEYDEEQARLMEEMCIVIDKDDKRLGADSKKTCHLMTNINEGLLHRAFSVFLFDSENRLLLQQRATEKITFPDMWTNTCCSHPLNTPSELVEEDQLGVRTAAQRKLEHELGIKPEEVPLDKFKYLTRIHYLAPSDGAWGEHEIDYILFMKADVHLDVNPNEIRDVKYVTPEELKAMFADPTIPMTPWFKLICNTFLFKWWSQIDTIDQIEPDHTIHRLGFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MZX1</accession>
    <name>A0A1C7MZX1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Putative transcription initiation factor TFIID subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">A0J61_09537</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000873">
        <property type="protein sequence ID" value="OBZ82410.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MZX1"/>
    <dbReference type="FunCoup" id="A0A1C7MZX1">
        <property type="interactions" value="48"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7MZX1"/>
    <dbReference type="InParanoid" id="A0A1C7MZX1"/>
    <dbReference type="OrthoDB" id="5752at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005669">
        <property type="term" value="C:transcription factor TFIID complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004402">
        <property type="term" value="F:histone acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016251">
        <property type="term" value="F:RNA polymerase II general transcription initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017025">
        <property type="term" value="F:TBP-class protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051123">
        <property type="term" value="P:RNA polymerase II preinitiation complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1100.10">
        <property type="entry name" value="TAFII-230 TBP-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040240">
        <property type="entry name" value="TAF1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022591">
        <property type="entry name" value="TAF1_HAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009067">
        <property type="entry name" value="TAF_II_230-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036741">
        <property type="entry name" value="TAFII-230_TBP-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13900">
        <property type="entry name" value="TRANSCRIPTION INITIATION FACTOR TFIID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13900:SF0">
        <property type="entry name" value="TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12157">
        <property type="entry name" value="DUF3591"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09247">
        <property type="entry name" value="TBP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47055">
        <property type="entry name" value="TAF(II)230 TBP-binding fragment"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="TAFII-230 TBP-binding" evidence="6">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="domain" description="Transcription initiation factor TFIID subunit 1 histone acetyltransferase" evidence="7">
        <location>
            <begin position="419"/>
            <end position="836"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="45"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="229"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="57"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="237"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="250"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="839"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF09247"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF12157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OBZ82410.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="839" mass="97043" checksum="5247CC8420413318" modified="2016-11-30" version="1" fragment="single">MSLAGYFFGNVDEQGRLESDLDEDLRETLSSVDANVMSKIFSGDTFGLENISRQPNESDDDDDDEPTQLSIPNMPTAHSKDAVDYSDFDEAIPDEQEKYYRRGMGMVQKNLPRSRLALVTDNYDSDEEEQEDIKQEPMELDLPEVSVAKPSTTSQTTTMDVQHIFPGFEKNKILKFSELFMTKIKRPPRLSAQKRIIYGDGYEYEMERDDRTAFLRTSKLDRFRIEQAKQNTKKRRIESQQRTLEHTSDIEEEEEEEEEEERIEQRTAELPKVIEDDKLYHSVMLEDWENEIVWGDDDDDDDDEDEAMEMIPVQGLASIGQEEKENAIKHLNMALEEGDWIDAIIWNNEKPDSSSMKIELDLNDPNMLFDVEEVEATKELLPQPKHVKKGRKPLPRPLPKIQIFHTETEPHNKLPLNRFNLSNDKHYESHLAGRLIRVRQTFGQLVVQHALPALKLHPALYKTKLSKQELRSFHRPLIQLPLNIDIHFSRMKASKKKKKDKKKGHVDIIRSTKDLTLKDSSSFVLMEYSEEHPPIISNMGMGTLVINYYRKTEPKDEFVPNMDIGEPFVLDIGDTSPFMTFGNVEPGQTISVYYNNLIRAPLFRHDVKHTDFLLIKSTYKDQTKYYLRDIPAIFTIGQSYPVQEVPGPHSRKVTTTIKNRLQVVAYRLIKRHNLQRLKMNRLAKKFPEYSDIQIRQRLKEFLEFHRRSKDGGGGYWKTRGGADPPSEEDLRKMVTPEMVCLYESMLVGERHLQDLGYGDVNDDDETGDGDSKLEVEQQLAPWFSTRNFINATQGKAMLKLYGAGDPTGRGEGFSFIRVSMKDIFLRAGESAEEKLAQIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N100</accession>
    <name>A0A1C7N100_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_10938</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001525">
        <property type="protein sequence ID" value="OBZ81014.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N100"/>
    <dbReference type="STRING" id="101091.A0A1C7N100"/>
    <dbReference type="InParanoid" id="A0A1C7N100"/>
    <dbReference type="OrthoDB" id="2239577at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00303">
        <property type="entry name" value="retropepsin_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.70.10">
        <property type="entry name" value="Acid Proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021109">
        <property type="entry name" value="Peptidase_aspartic_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13975">
        <property type="entry name" value="gag-asp_proteas"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50630">
        <property type="entry name" value="Acid proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="35"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="176"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="44"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ81014.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="456" mass="50224" checksum="EB3A5CA7555F4079" modified="2016-11-30" version="1">MDKISSQKHNNNPVVNCFVKVAPNTLVNAVEVNNVGKRNRNNNSETTQEGVTHNASKRQTRQQFAPPVTLPSPGAATLPVIAPQGTTYMPMSHPIATTSGQPVGPPGGFVVQPQVTPVAPPLKTKKLRAPPRKLPVPKREIDTWEKLDSIMAPISFKDWMVNDKNARKQLKDGLRFLDARNPTRRKDKGKGKEATAGQVNLVEATTSDSDDYSTTETDSTKSTYDDTEDYTSDVYDSDDDTIYDYPYRKEALLQSSPFYVMGTIHDRQVQVVIDSGSAVSVISKSFAKTLGLTGVGERVPITTLDTTKKDQKRGNQKGDCEVTVAVPIRIGGKLRIEHMIMKDDSNRSKGDPIVLLGMTWLKQHVIKIHSKETIIEIPIKNGASSILIQGFLTDHFSDDTPKQVFSVSVQAPVKKNIKYQVELVDIESWAAGMSDEDPSVEVYHTILSSSNGSKDH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N1K0</accession>
    <name>A0A1C7N1K0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_10707</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001332">
        <property type="protein sequence ID" value="OBZ81244.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N1K0"/>
    <dbReference type="InParanoid" id="A0A1C7N1K0"/>
    <dbReference type="OrthoDB" id="6141723at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ81244.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="109" mass="12645" checksum="BAE0A59179C4B5A3" modified="2016-11-30" version="1" fragment="single">PMSETQIEEARARNCESQRASRQRRRQLEINRDDVNPSELIVQKYQDEIRKGLTAVCVCCGGLRFSDQTKSVTKESLLARNANQEFVHNVFKFNKQQESNVFASIAHWM</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N1P2</accession>
    <name>A0A1C7N1P2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_08973</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000746">
        <property type="protein sequence ID" value="OBZ82977.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N1P2"/>
    <dbReference type="InParanoid" id="A0A1C7N1P2"/>
    <dbReference type="OrthoDB" id="2282388at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ82977.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="71" mass="8434" checksum="F881719F2C3EEB0F" modified="2016-11-30" version="1">MAFFQTDIDPIYLREQHRKVMTTEKQPIKQASQIPQHQTLFQILFSTTPFEIKPRSTITTDSMNRLVSFYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N1Z9</accession>
    <name>A0A1C7N1Z9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Dolichyl-diphosphooligosaccharide-protein glycosyltransferase subunit OST5</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">A0J61_08809</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Component of the oligosaccharyltransferase (OST) complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Membrane</location>
            <topology evidence="1 6">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the OST5 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000715">
        <property type="protein sequence ID" value="OBZ83143.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N1Z9"/>
    <dbReference type="STRING" id="101091.A0A1C7N1Z9"/>
    <dbReference type="InParanoid" id="A0A1C7N1Z9"/>
    <dbReference type="OrthoDB" id="18408at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008250">
        <property type="term" value="C:oligosaccharyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006487">
        <property type="term" value="P:protein N-linked glycosylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007915">
        <property type="entry name" value="TMEM258/Ost5"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05251">
        <property type="entry name" value="Ost5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="20"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="54"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU367008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OBZ83143.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="78" mass="8090" checksum="C0931F3971F4B228" modified="2016-11-30" version="1">MTALDDWTTGTPISATIPTSVYPVVTLVTLSAGVFTAGNFIIQDKKTPVTQQLQTAMIASLLLGFGAIFAANAAGLYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N2C1</accession>
    <name>A0A1C7N2C1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">cAMP-dependent protein kinase</fullName>
            <ecNumber evidence="1">2.7.11.11</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">PRKACB_0</name>
        <name evidence="14" type="ORF">A0J61_10449</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.11"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.11"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the protein kinase superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.11" evidence="1"/>
    <dbReference type="EMBL" id="LUGH01001178">
        <property type="protein sequence ID" value="OBZ81504.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N2C1"/>
    <dbReference type="STRING" id="101091.A0A1C7N2C1"/>
    <dbReference type="InParanoid" id="A0A1C7N2C1"/>
    <dbReference type="OrthoDB" id="63267at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005952">
        <property type="term" value="C:cAMP-dependent protein kinase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004691">
        <property type="term" value="F:cAMP-dependent protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd05580">
        <property type="entry name" value="STKc_PKA_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000005">
        <property type="entry name" value="cAMP-dependent protein kinase catalytic subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000005">
        <property type="entry name" value="cAMP-dependent protein kinase catalytic subunit alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000961">
        <property type="entry name" value="AGC-kinase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24353:SF37">
        <property type="entry name" value="CAMP-DEPENDENT PROTEIN KINASE CATALYTIC SUBUNIT PRKX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24353">
        <property type="entry name" value="CYCLIC NUCLEOTIDE-DEPENDENT PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00133">
        <property type="entry name" value="S_TK_X"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51285">
        <property type="entry name" value="AGC_KINASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 14" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 9 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 10" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="12">
        <location>
            <begin position="74"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="domain" description="AGC-kinase C-terminal" evidence="13">
        <location>
            <begin position="317"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="103"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="non-terminal residue" evidence="14">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012444"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047292"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00047454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="OBZ81504.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="373" mass="43090" checksum="E1E4F88A35EAA1F9" modified="2016-11-30" version="1" fragment="single">KNRMNNKPQVYLSNPRPLLKRPMDNNAFPPNHPLANLPIPSPTPYQQQQAARLHYYHTRPSAYVENPSFGLKDFELQDTLGTGTFGRVYLSKFIPSSKFYAMKVLKKSEVVRLKQVEHLMSEKQILSSVRFPFIVDLFCTFQDETNLYMLLEYVVGGELFTHLRRAGRFTNDMTRFYASEIVLAIEYLHSKDIIYRDLKPENLLIDHQGHIKITDFGFAKKVVDRTWTLCGTPEYLAPEIIQSKGHGKAVDWWALGILIFEMLAGYPPFFDDNSFGIYEKILMGKVQFAAHFDPLAKDLLKRLLGGSEDVKRHKWFRGVDWIGLLDKNVRAPIIPHYPHPGDTSNFEKYPEQFDTESNLDGDPYKELFVGFSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N2F7</accession>
    <name>A0A1C7N2F7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Transmembrane protein 198</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">A0J61_08669</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TMEM198 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000690">
        <property type="protein sequence ID" value="OBZ83282.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N2F7"/>
    <dbReference type="STRING" id="101091.A0A1C7N2F7"/>
    <dbReference type="InParanoid" id="A0A1C7N2F7"/>
    <dbReference type="OrthoDB" id="102260at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025256">
        <property type="entry name" value="TM7S3/TM198-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040236">
        <property type="entry name" value="TMEM198"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31247:SF5">
        <property type="entry name" value="DUF4203 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31247">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 198 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13886">
        <property type="entry name" value="TM7S3_TM198"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0732">Signal</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008889446" description="Transmembrane protein 198" evidence="9">
        <location>
            <begin position="23"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="148"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="173"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="203"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="226"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="256"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="288"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="330"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="domain" description="TM7S3/TM198-like" evidence="10">
        <location>
            <begin position="151"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="365"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="367"/>
            <end position="382"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00049737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF13886"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="OBZ83282.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="416" mass="46128" checksum="1F19F140CEC329DC" modified="2016-11-30" version="1">MKKVTLSLAFILLLSLIESSLCITLPTKTAYALQTKTIVSVKTPTNAPLRKRDVEDDLELYQNWASMCRNRDNHKELVASAAVSGLNDLWKTVTQTVNCGGGTAVTVTTTVQATPTSKPPSKSPSCEGQCWSDYLWHTYGDSISPAQGFIGTLCIIVGLYFAIFGYRFFRPTLGLVGFVFFATMTWIGLVNNEPAGGYPLGDVIYICVSAGLGILGALILIFLYPLGVYCLACLGGFYLAVYILSWKEDLVITIKVARVCFIIGLSLLGPVLLFFIETYMVIFSTALIGAYLFYFGLDFFAHTGFINPWLLIFDGNPIHHNVYLMSKPVYIMLAFVIVNTLISVGWQYYWNIICLKSPGFGLNPPVETEKEKPPPPPPEKEPCPPPPTYVCMPPPYYSQQPMIMQQVCAPQYHPHQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N2J5</accession>
    <name>A0A1C7N2J5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Sphingosine N-acyltransferase lag1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">lag1_0</name>
        <name evidence="10" type="ORF">A0J61_08743</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the sphingosine N-acyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000702">
        <property type="protein sequence ID" value="OBZ83208.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N2J5"/>
    <dbReference type="STRING" id="101091.A0A1C7N2J5"/>
    <dbReference type="InParanoid" id="A0A1C7N2J5"/>
    <dbReference type="OrthoDB" id="537032at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050291">
        <property type="term" value="F:sphingosine N-acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046513">
        <property type="term" value="P:ceramide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016439">
        <property type="entry name" value="Lag1/Lac1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006634">
        <property type="entry name" value="TLC-dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12560:SF0">
        <property type="entry name" value="LD18904P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12560">
        <property type="entry name" value="LONGEVITY ASSURANCE FACTOR 1 LAG1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03798">
        <property type="entry name" value="TRAM_LAG1_CLN8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005225">
        <property type="entry name" value="LAG1_LAC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00724">
        <property type="entry name" value="TLC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50922">
        <property type="entry name" value="TLC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="5 6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0808">Transferase</keyword>
    <keyword evidence="3 6 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="34"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="72"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="118"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="190"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="232"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="295"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="domain" description="TLC" evidence="9">
        <location>
            <begin position="112"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="329"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="333"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="343"/>
            <end position="353"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009808"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00205"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OBZ83208.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="366" mass="42805" checksum="EAD17675BE4F820A" modified="2016-11-30" version="1">MAKHTPQKSALNKKAERNSLSDLSKYLADHQIEIPLKVIGFILSGCLLRLPFFHNFVFISNQRSDGRFEKSFWDLAFLFFYICVFTALRAAIMDYVLIPLAKCANVSAKKYQRFAEQSWSCLYYSSAFAFGTYVMKDEPWWFDSTYFWRDYPVTDYTKSFKYYYLVQFAYWLQQIFVLQIEAPRKDYKELVMHHINTLLLVSLSYCCNFTRVGNAVFVCMDLPDAFLALAKTLNYACPGLICNTVFGLMVCSWMYSRVYLYGCIIVSTLTEPELYVPVFKLDPLNGHWFPYFVKYIIAGLMIGLYFLILFWTVMIFKVIYKICTDTEPKDVRSDDEDETEDISIEKIEGDHSTPKPTARNLNKKVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N2S5</accession>
    <name>A0A1C7N2S5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Mannosyltransferase</fullName>
            <ecNumber evidence="12">2.4.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">A0J61_09032</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Mannosyltransferase that operates in the biosynthetic pathway of dolichol-linked oligosaccharides, the glycan precursors employed in protein asparagine (N)-glycosylation. The assembly of dolichol-linked oligosaccharides begins on the cytosolic side of the endoplasmic reticulum membrane and finishes in its lumen. The sequential addition of sugars to dolichol pyrophosphate produces dolichol-linked oligosaccharides containing fourteen sugars, including two GlcNAcs, nine mannoses and three glucoses. Once assembled, the oligosaccharide is transferred from the lipid to nascent proteins by oligosaccharyltransferases. In the lumen of the endoplasmic reticulum, adds the eighth mannose residue in an alpha-1,6 linkage onto Man(7)GlcNAc(2)-PP-dolichol to produce Man(8)GlcNAc(2)-PP-dolichol.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>an alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;3)-alpha-D-Man-(1-&gt;6)]-beta-D-Man-(1-&gt;4)-beta-D-GlcNAc-(1-&gt;4)-alpha-D-GlcNAc-diphospho-di-trans,poly-cis-dolichol + a di-trans,poly-cis-dolichyl beta-D-mannosyl phosphate = an alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;6)]-alpha-D-Man-(1-&gt;6)]-beta-D-Man-(1-&gt;4)-beta-D-GlcNAc-(1-&gt;4)-alpha-D-GlcNAc-diphospho-di-trans,poly-cis-dolichol + a di-trans,poly-cis-dolichyl phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:29535"/>
            <dbReference type="Rhea" id="RHEA-COMP:19498"/>
            <dbReference type="Rhea" id="RHEA-COMP:19501"/>
            <dbReference type="Rhea" id="RHEA-COMP:19518"/>
            <dbReference type="Rhea" id="RHEA-COMP:19519"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57683"/>
            <dbReference type="ChEBI" id="CHEBI:58211"/>
            <dbReference type="ChEBI" id="CHEBI:132517"/>
            <dbReference type="ChEBI" id="CHEBI:132519"/>
            <dbReference type="EC" id="2.4.1.260"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="11">
            <dbReference type="Rhea" id="RHEA:29536"/>
        </physiologicalReaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 12">Endoplasmic reticulum membrane</location>
            <topology evidence="1 12">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 12">Belongs to the glycosyltransferase 22 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.-" evidence="12"/>
    <dbReference type="EMBL" id="LUGH01000758">
        <property type="protein sequence ID" value="OBZ82919.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N2S5"/>
    <dbReference type="FunCoup" id="A0A1C7N2S5">
        <property type="interactions" value="205"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N2S5"/>
    <dbReference type="InParanoid" id="A0A1C7N2S5"/>
    <dbReference type="OrthoDB" id="19039at2759"/>
    <dbReference type="UniPathway" id="UPA00378"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052917">
        <property type="term" value="F:dol-P-Man:Man(7)GlcNAc(2)-PP-Dol alpha-1,6-mannosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006487">
        <property type="term" value="P:protein N-linked glycosylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd03419">
        <property type="entry name" value="GRX_GRXh_1_2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002109">
        <property type="entry name" value="Glutaredoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005599">
        <property type="entry name" value="GPI_mannosylTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22760:SF1">
        <property type="entry name" value="DOL-P-MAN:MAN(7)GLCNAC(2)-PP-DOL ALPHA-1,6-MANNOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22760">
        <property type="entry name" value="GLYCOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00462">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03901">
        <property type="entry name" value="Glyco_transf_22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51354">
        <property type="entry name" value="GLUTAREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 12" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="4 12 15" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="9 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="13" id="KW-0732">Signal</keyword>
    <keyword evidence="5 15" id="KW-0808">Transferase</keyword>
    <keyword evidence="6 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 12" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="13">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008889451" description="Mannosyltransferase" evidence="13">
        <location>
            <begin position="17"/>
            <end position="587"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="56"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="83"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="170"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="255"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="339"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="domain" description="Glutaredoxin" evidence="14">
        <location>
            <begin position="514"/>
            <end position="561"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00044721"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00048899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU363075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF00462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="OBZ82919.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="587" mass="67459" checksum="B7A33F21C4FC85AA" modified="2016-11-30" version="1">MKLVLGSLFILIAIEAYLAPYTKVEESFNLQATHDLLHRVDRYDHLDFSGVVPRTFLGATLLSALSWPILQLFPNLSLLDQQVLVRILLAALVVFALGQFASSVRVTFSTESAKLTIVLLLCQFHLVFWSSRTLPNTLALPWTVLGLSHWLSSLGQVQDRAYHLKWMIRYLTFAGVVFRFEVGIFLVVLLGFEMFYGTIGWRSILKQMLLTAFVALVLSVPLDSYMWEQWIWPEWVVFYFNVILNKSSEWGALPFHAYVFSFLPRLLLISYPLGIIGFVRDNRIRRLLMPAVVYVFIFSCLPHKEWRFIVYTIPLFTTAAAVTIQDFRVASYRSWFYKAVLLVVLGGAVVSFLISITLFQISRLNYPGGDALARLHALEANHVYVSVHMDPETCMTGASLYGQLYPHWKYSKNESHLTEQDFIEARYTHLITAHPERVDSERFELMDTIYGLDKVKLKSLKEYKRSITHYDVIPIRFELAPKLYILKLIEPHRVWVEDTVQKHPVVLYSKTYWAAKQLISKYCKDIHVIEVDQEPNGYEIKQALYALTGQATFPNLFQHGKSLGGYDRLSALDRQGSLAGLCSDRAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N2S7</accession>
    <name>A0A1C7N2S7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Lysine-specific permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">lysP_0</name>
        <name evidence="10" type="ORF">A0J61_08546</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000669">
        <property type="protein sequence ID" value="OBZ83400.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N2S7"/>
    <dbReference type="FunCoup" id="A0A1C7N2S7">
        <property type="interactions" value="426"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N2S7"/>
    <dbReference type="InParanoid" id="A0A1C7N2S7"/>
    <dbReference type="OrthoDB" id="3900342at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015171">
        <property type="term" value="F:amino acid transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1740.10:FF:000001">
        <property type="entry name" value="Amino acid permease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1740.10">
        <property type="entry name" value="Amino acid/polyamine transporter I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004841">
        <property type="entry name" value="AA-permease/SLC12A_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004840">
        <property type="entry name" value="Amino_acid_permease_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050524">
        <property type="entry name" value="APC_YAT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43341">
        <property type="entry name" value="AMINO ACID PERMEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43341:SF1">
        <property type="entry name" value="GENERAL AMINO-ACID PERMEASE GAP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00324">
        <property type="entry name" value="AA_permease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00218">
        <property type="entry name" value="AMINO_ACID_PERMEASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0029">Amino-acid transport</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="82"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="163"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="191"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="221"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="259"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="300"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="341"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="399"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="432"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="471"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="505"/>
            <end position="522"/>
        </location>
    </feature>
    <feature type="domain" description="Amino acid permease/ SLC12A" evidence="9">
        <location>
            <begin position="81"/>
            <end position="529"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="9"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="41"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OBZ83400.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="587" mass="63908" checksum="310B6D5613091989" modified="2016-11-30" version="1">MFSGKGKGKSNEDRNSRNDIVEEIDMKDIHKNMRSRSTSSDNKETGHPEEASRVYSRGQSGSIGDIIDDKPQLQRGLKARHLTMISLGGTIGTGLFLASGASVANAGPGGALIAYGMIGIMVFFMMECLGEMATFLPISGSFNNYAGRFIDPAIGFALGWNYWYNWAVTVAVELTAGSMVMAYWAPWVPGYVWSICFLVIILSLNLFSVKGYGEAEYWFALIKVLTVIVFIILGILVDTAVLGGVYYGVSNFNYGGVQGLGVLTTFLTAGFSFQGTELIGVAAGESENPRKNVPRAIKQVFWRILLFYILSILMIGLIIPYDDPKLLSSDVTNISVSPFTLVFIKAGIPPAAHVMNAVILTTVLSAGNSGLYASSRTLLDLANEGKAPKIFRKITKNGIPIYCVLLTAAIGMLAFLTSLFGNGVVYNWLMNISGIAGFIAWLGIAAAHWRFRRAYVAQGYKVSDLPFKARLFPLGPIFAFCVCLFVIVGQGYNAWSAVPVNPSDIIAAYIGVPVVLIFYLGYKITKKTKVIPLMEVDLITGRENIGHGGDSDDDKKSDPLEGVSIFKPATWKRIPSNLKSWRDAFHN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N2T4</accession>
    <name>A0A1C7N2T4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_09022</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000756">
        <property type="protein sequence ID" value="OBZ82929.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N2T4"/>
    <dbReference type="FunCoup" id="A0A1C7N2T4">
        <property type="interactions" value="193"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N2T4"/>
    <dbReference type="InParanoid" id="A0A1C7N2T4"/>
    <dbReference type="OrthoDB" id="415411at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047429">
        <property type="term" value="F:nucleoside triphosphate diphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017111">
        <property type="term" value="F:ribonucleoside triphosphate phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009141">
        <property type="term" value="P:nucleoside triphosphate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd16018">
        <property type="entry name" value="Enpp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1360.180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.720.10">
        <property type="entry name" value="Alkaline Phosphatase, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017850">
        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002591">
        <property type="entry name" value="Phosphodiest/P_Trfase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10151:SF120">
        <property type="entry name" value="BIS(5'-ADENOSYL)-TRIPHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10151">
        <property type="entry name" value="ECTONUCLEOTIDE PYROPHOSPHATASE/PHOSPHODIESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01663">
        <property type="entry name" value="Phosphodiest"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53649">
        <property type="entry name" value="Alkaline phosphatase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="71"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="13"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="23"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ82929.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="515" mass="58406" checksum="DA1077815642FCE3" modified="2016-11-30" version="1">MPQEAEEVFEMSRSVSGGSSTLDFEHTEQDQLLSKEDQSDSDQDLDEQDEAWAIMMEEGGDSDTYEHDNLLLRYVCIGLAVGLFFIIFKIGMNKLAMHSGHHERAAEKLYYNGSDYFASTVILISLDGFRPDYLDRGITPHLNALASQGAMAKYMHPSFPPSTFPNHWTLVTGLYPETHGVVANLFYDPTMDTTFSHTNHTATSDHRWWKGEPIWVTSKINRRRSGSIMWPGSDTNFNPPDLVVPYDDTMGTKEKMDTVLQWLDMPYNSRPEIITVHVPQVDQEGHRAGPYGAKMNTFIKEIDNAIGYLVAQLETRSLDSHAHIVVVSDHGMAETGPSKLIYYDDILSKDTLQYIQQREALPLLDLRLQKEAPQDTVQRIYHELATYAQNNTNAHYQVYLREDVPERYHYSHSDRITPIVAIPDVGYTFVTHAEVKHDRFISGGNHGYDNLADDMRAIFIAKGPKVSRIFKEGTILAPFFNIEIYGFVTELLNIDAAPNNGTLRGEFPVLFSPPF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N323</accession>
    <name>A0A1C7N323_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">AP-1-like transcription factor CAP1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">CAP1</name>
        <name evidence="7" type="ORF">A0J61_08909</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000734">
        <property type="protein sequence ID" value="OBZ83039.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N323"/>
    <dbReference type="STRING" id="101091.A0A1C7N323"/>
    <dbReference type="InParanoid" id="A0A1C7N323"/>
    <dbReference type="OrthoDB" id="2593073at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090575">
        <property type="term" value="C:RNA polymerase II transcription regulator complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001228">
        <property type="term" value="F:DNA-binding transcription activator activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000976">
        <property type="term" value="F:transcription cis-regulatory region binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033554">
        <property type="term" value="P:cellular response to stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd14688">
        <property type="entry name" value="bZIP_YAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.170">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.100">
        <property type="entry name" value="YAP1 redox domain. Chain B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050936">
        <property type="entry name" value="AP-1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004827">
        <property type="entry name" value="bZIP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046347">
        <property type="entry name" value="bZIP_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013910">
        <property type="entry name" value="TF_PAP1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023167">
        <property type="entry name" value="Yap1_redox_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40621:SF6">
        <property type="entry name" value="AP-1-LIKE TRANSCRIPTION FACTOR YAP1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40621">
        <property type="entry name" value="TRANSCRIPTION FACTOR KAPC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00170">
        <property type="entry name" value="bZIP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08601">
        <property type="entry name" value="PAP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00338">
        <property type="entry name" value="BRLZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57959">
        <property type="entry name" value="Leucine zipper domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111430">
        <property type="entry name" value="YAP1 redox domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50217">
        <property type="entry name" value="BZIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00036">
        <property type="entry name" value="BZIP_BASIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BZIP" evidence="6">
        <location>
            <begin position="135"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="53"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="105"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="227"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="153"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="53"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="230"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="251"/>
            <end position="261"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OBZ83039.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="389" mass="45221" checksum="C609A02779EB6F90" modified="2016-11-30" version="1">MQNPSFFSFLLFDTAKIPSSSTTIHHKSMTDSDPTYWQNFQSSEIVSPPTNNLLLSQQQSSPPHHHHQQQQWSEDSEKRKWAPDFQDFDINTHANKVFHMDEYHNEPSENESQETASISNRRNHVSPDPMEFQGGDQKQRRKEQNRAAQRAFRERKERYVKELQIKIRDMEKKHNEEITRVVDENKRLKDLVKKMEIEIYTLKGAAMAFDVSLRKLREAGLDVPSAKSIMRRDSPPPSILDRRSSPDRDCQSTASSIVTSSTEKRSYDPLFDSAHRYNSTPSRQHRPNSTDTTDDDHTIEDDDEAVVSFAESETRRFDHTVDPIVHSGHKMIPCSQIWERLAQHPNFDDFDVDRLCEELKKKARCSGSGPVIPEFELQEVLRRMDAKQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N357</accession>
    <name>A0A1C7N357_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">B box-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_08515</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000663">
        <property type="protein sequence ID" value="OBZ83438.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N357"/>
    <dbReference type="InParanoid" id="A0A1C7N357"/>
    <dbReference type="OrthoDB" id="406045at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018553">
        <property type="entry name" value="E2_Ub-conjug_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057668">
        <property type="entry name" value="E2_Ub-conjug_enz_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000315">
        <property type="entry name" value="Znf_B-box"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31560">
        <property type="entry name" value="UPF0652 PROTEIN C16A11.03C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31560:SF0">
        <property type="entry name" value="UPF0652 PROTEIN C22H10.08"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22586">
        <property type="entry name" value="ANCHR-like_BBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09418">
        <property type="entry name" value="DUF2009"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50119">
        <property type="entry name" value="ZF_BBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="B box-type" evidence="2">
        <location>
            <begin position="10"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ83438.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="568" mass="65092" checksum="64E1EB491A8D4083" modified="2016-11-30" version="1">MENLIASDSNKTVFCVECNDQEASIFCEQCDEDFCEVCHGMLHRTGNRKLHTAKKLNSHPTHHNTDVTTQVNVEKPEKQKDDTVMKQALMELDGTIINSSGPTFGDYMTKRSKTVPLRLDSEERQYLRLLEAALNVSEYTDKIDIISYSNKAKRIVGQIKDLCAILSGLLVAGDYKTGAQLFASRTVRENEAIFQRIFEVGRRHKIMNPEKMRSTYGKLMYMLMDSVIPEVTDYLGFSCVIPIKTVYDFLKSRESIDVLHDDSIVLATREISPDFKTREQIDAEVQRKQSAIRSICEKYANERISKEEIERCLLSMSDNNAFLMANRDPCDKMLKYLSKYFTPHKHDHGYSLAIQNGRNGHRLTHSHSAQYTYVHQSLTLWREIMNEMFMLWSMADEDLISPSAYRLTNTGQGLQRIQPCPHVSKAIHKILNRVHKKCGSWVGSSVVHLGDKNVPNSFMFIDKYNQVARILTPIVSTLDKLDYFENDVDLLDYVKNTYGSIEQCKKDILYDLFTFGFDGSGGDNYFDAGSCIDGRLTSAWNWCSTIEKKKFFPIFLMTGFIGFDGSEW</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N4B0</accession>
    <name>A0A1C7N4B0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Putative glucuronosyltransferase GUT1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">GUT1</name>
        <name evidence="4" type="ORF">A0J61_07987</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the glycosyltransferase 47 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000577">
        <property type="protein sequence ID" value="OBZ83965.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N4B0"/>
    <dbReference type="STRING" id="101091.A0A1C7N4B0"/>
    <dbReference type="InParanoid" id="A0A1C7N4B0"/>
    <dbReference type="OrthoDB" id="1924787at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004263">
        <property type="entry name" value="Exostosin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040911">
        <property type="entry name" value="Exostosin_GT47"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11062">
        <property type="entry name" value="EXOSTOSIN HEPARAN SULFATE GLYCOSYLTRANSFERASE -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11062:SF281">
        <property type="entry name" value="EXOSTOSIN-LIKE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03016">
        <property type="entry name" value="Exostosin_GT47"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008889478" evidence="2">
        <location>
            <begin position="29"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="domain" description="Exostosin GT47" evidence="3">
        <location>
            <begin position="60"/>
            <end position="369"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010271"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF03016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OBZ83965.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="418" mass="49651" checksum="4EFDA3A833717E13" modified="2016-11-30" version="1">MAVVLRFNRRWLISIALLSLFLLSCVLLKNRSPAPPAPPLPIRDSPSYWPTPLEQAFCRPKIYVYKAPSSFQVSQKVQEEQCHESNYNSEIILHNQLTDPTSPIYHHYVTENPEEADFFLIPFFGACYLYHCWGSHGWDWNERCDVDRLYVDPMMDMIIHQYPYWNQSNGKDHIMIHPMDKTFTYYQHHVRFQPAIFMTTVGDKRQKWMDRHRYHRDIVIPSATRMIHHLQINPLDYLTPDGHPKSGKRDIFVLFQGCCDNVKPEDEYSNGIRSLFFDHFKHYPGYEIGQVIADLEYVNKLSRARYGLSPMGWTLDTTRIWEFMAFGVVPVVIADGIIEPFEFDVDWDSFVVRVRRDEVHRLDQILRKIDDQTYEYKRRKLWEYGRRVGLEMDAWHYIVRDLCRMENINAPVNLGLGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N4C3</accession>
    <name>A0A1C7N4C3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Vacuolar transporter chaperone complex subunit 4</fullName>
            <ecNumber evidence="3">2.7.4.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13">Polyphosphate kinase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="12">SPX-dependent polyphosphate polymerase VTC subunit 4</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="14">Vacuolar membrane polyphosphate polymerase catalytic subunit</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="17" type="primary">vtc4_8</name>
        <name evidence="17" type="ORF">A0J61_08074</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>[phosphate](n) + ATP = [phosphate](n+1) + ADP</text>
            <dbReference type="Rhea" id="RHEA:19573"/>
            <dbReference type="Rhea" id="RHEA-COMP:9859"/>
            <dbReference type="Rhea" id="RHEA-COMP:14280"/>
            <dbReference type="ChEBI" id="CHEBI:16838"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.4.1"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="9">
            <dbReference type="Rhea" id="RHEA:19574"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Vacuole membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the VTC4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.4.1" evidence="3"/>
    <dbReference type="EMBL" id="LUGH01000590">
        <property type="protein sequence ID" value="OBZ83878.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N4C3"/>
    <dbReference type="STRING" id="101091.A0A1C7N4C3"/>
    <dbReference type="InParanoid" id="A0A1C7N4C3"/>
    <dbReference type="OrthoDB" id="6493944at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000329">
        <property type="term" value="C:fungal-type vacuole membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033254">
        <property type="term" value="C:vacuolar transporter chaperone complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008976">
        <property type="term" value="F:polyphosphate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006799">
        <property type="term" value="P:polyphosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd07751">
        <property type="entry name" value="PolyPPase_VTC4_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd14480">
        <property type="entry name" value="SPX_VTC2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.100.30:FF:000001">
        <property type="entry name" value="Vacuolar transporter chaperone 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.100.30">
        <property type="entry name" value="VTC, catalytic tunnel domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004331">
        <property type="entry name" value="SPX_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051572">
        <property type="entry name" value="VTC_Complex_Subunit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018966">
        <property type="entry name" value="VTC_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042267">
        <property type="entry name" value="VTC_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46140">
        <property type="entry name" value="VACUOLAR TRANSPORTER CHAPERONE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46140:SF2">
        <property type="entry name" value="VACUOLAR TRANSPORTER CHAPERONE 3 COMPLEX SUBUNIT 3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03105">
        <property type="entry name" value="SPX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09359">
        <property type="entry name" value="VTC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51382">
        <property type="entry name" value="SPX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0926">Vacuole</keyword>
    <feature type="domain" description="SPX" evidence="16">
        <location>
            <begin position="1"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="513"/>
            <end position="564"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="15">
        <location>
            <begin position="530"/>
            <end position="539"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="15">
        <location>
            <begin position="555"/>
            <end position="564"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022554"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00050204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00061390"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00067464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00075894"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00080494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00081313"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS51382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="OBZ83878.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="564" mass="65951" checksum="2FCD962B11B86854" modified="2016-11-30" version="1">MKFADQLKQGIFAPWRLSYINYDILKTELKARQLDHGWTDQDEKDFVHLLENELDKVYDFISAKLGEVEARISYCERTLQTFMNNPSWSSEQNWNIMDDALTEVLFDVNDLAKFTRLNYIGFQKILKKHDKWTGLHLQQSFIPQLRAKPLDKQRFDVAIVYISALHDLCRLQGKPRTGNSAAGGDQNAFERATAKYWIHPDNVTEVKSIIMLHLPVLIFNKDKKFEASDSAISSIYYDNEDFDLYTGRLQRDEGAEAIRFRWYGPMESKSVFIERKTHHASWLDGASVKDRFRLDVDDVKKYIEYELTPDEITDRLRQKNVDEQICKDTHFIATGVQKSLKEKQLNPVLRAFYNRTAFQLPGDQRVRVSLDTDLCFIREDNLDKERRGQGEWRRPDVGIDCPFPALDETEICRFPYAVLETKLQTHLGQEPPEWLTKLVESHLVHEVPRFSKYLHGACYFFRERMPLLPWWLPEMDIDIRKPRATNFGLTRSKSFKPLIDGQYRRAMEAEERRLNSAAKTESVPGVKVNTGEEKTELKRTKPKPNANFDLKRRTPSSQLAQAKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N4U7</accession>
    <name>A0A1C7N4U7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Vesicular inhibitory amino acid transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">slc32a1_3</name>
        <name evidence="10" type="ORF">A0J61_07905</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the amino acid/polyamine transporter 2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000564">
        <property type="protein sequence ID" value="OBZ84047.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N4U7"/>
    <dbReference type="InParanoid" id="A0A1C7N4U7"/>
    <dbReference type="OrthoDB" id="40134at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005774">
        <property type="term" value="C:vacuolar membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015179">
        <property type="term" value="F:L-amino acid transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1740.10">
        <property type="entry name" value="Amino acid/polyamine transporter I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013057">
        <property type="entry name" value="AA_transpt_TM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22950">
        <property type="entry name" value="AMINO ACID TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22950:SF692">
        <property type="entry name" value="TRANSMEMBRANE AMINO ACID TRANSPORTER FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01490">
        <property type="entry name" value="Aa_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0029">Amino-acid transport</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="45"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="72"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="118"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="159"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="184"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="224"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="257"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="301"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="346"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="372"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="403"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="domain" description="Amino acid transporter transmembrane" evidence="9">
        <location>
            <begin position="43"/>
            <end position="423"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008066"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OBZ84047.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="433" mass="47417" checksum="DB58143EC7C9AD71" modified="2016-11-30" version="1">MSIKEKELEQKIPTENSSSILEENDFEFEDSGFIDVDRTNGCSSLVAFFNIFCVVAGTGILGLPYALRQGGFIGLVILFLSWSMSTYTATILIRCLYANGKARLATYKEIATSSFGWLGGWLTFFFNAWIVLGVPILYLXLSGTNINTLCRGTSAELGLKPWIIICCVIVGIPFVLIKSMKEAAWMSTLSTLTIMVVVVIVLVMCGVDSPNHTNVHHDVVIWDMFPVALSTISFSFGGNVVYTHVEASMKRPQDWTKISVASLSTCAILYLCVAIAGYIVYGNQVSNPVYFSIPAGPPQTVVIVLITIHCLATTPILTTSFGLDIEELFDINVERFGKVKEFIIRAAVRIATMVVIAIVACFVPHFGALMSLIGAFANCTMVFALPIFCYLKLTGVRNKPFYELAWCALTVLLGIVGLIFGTIDAIKELKSSY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N4Z1</accession>
    <name>A0A1C7N4Z1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">3-oxoacyl-[acyl-carrier-protein] reductase FabG</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">fabG_0</name>
        <name evidence="5" type="ORF">A0J61_08222</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000613">
        <property type="protein sequence ID" value="OBZ83726.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N4Z1"/>
    <dbReference type="STRING" id="101091.A0A1C7N4Z1"/>
    <dbReference type="InParanoid" id="A0A1C7N4Z1"/>
    <dbReference type="OrthoDB" id="5840532at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016616">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44229">
        <property type="entry name" value="15-HYDROXYPROSTAGLANDIN DEHYDROGENASE [NAD(+)]"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44229:SF4">
        <property type="entry name" value="15-HYDROXYPROSTAGLANDIN DEHYDROGENASE [NAD(+)]"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OBZ83726.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="258" mass="28714" checksum="CA7A35D5E3780041" modified="2016-11-30" version="1">MLNFIKKKKNRANVIFSGTNKQKGQDVLDSLNKLHKGRCDRNAIFYSMNVTDWKAQEDIYSVAEKTFGKTVDIVIMVAGILDSSSLVKDVENDGHYMTIDVNLTATVKANRLAIQYFLKNKKSGCVINTSSVYGLTAGPTAPMYAATKHAIIGLTKSYGNLLRSTDIRVNAIAPHFTPMIPGESYKVARAFGMVPIEDCIKAYLQAIQDESLNGDILSVSHLGTMVEPRFATTLLEQLDDFSHKRREDVLNNLLEEFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N561</accession>
    <name>A0A1C7N561_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Mitotic spindle checkpoint component mad2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">mad2</name>
        <name evidence="8" type="ORF">A0J61_08166</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the MAD2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000605">
        <property type="protein sequence ID" value="OBZ83779.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N561"/>
    <dbReference type="FunCoup" id="A0A1C7N561">
        <property type="interactions" value="891"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N561"/>
    <dbReference type="InParanoid" id="A0A1C7N561"/>
    <dbReference type="OrthoDB" id="1806at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000785">
        <property type="term" value="C:chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000776">
        <property type="term" value="C:kinetochore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990333">
        <property type="term" value="C:mitotic checkpoint complex, CDC20-MAD2 subcomplex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990498">
        <property type="term" value="C:mitotic spindle microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044732">
        <property type="term" value="C:mitotic spindle pole body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034399">
        <property type="term" value="C:nuclear periphery"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005654">
        <property type="term" value="C:nucleoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010997">
        <property type="term" value="F:anaphase-promoting complex binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:1905318">
        <property type="term" value="P:meiosis I spindle assembly checkpoint signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044774">
        <property type="term" value="P:mitotic DNA integrity checkpoint signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007094">
        <property type="term" value="P:mitotic spindle assembly checkpoint signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902499">
        <property type="term" value="P:positive regulation of protein autoubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.900.10">
        <property type="entry name" value="HORMA domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003511">
        <property type="entry name" value="HORMA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036570">
        <property type="entry name" value="HORMA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045091">
        <property type="entry name" value="Mad2-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11842">
        <property type="entry name" value="MITOTIC SPINDLE ASSEMBLY CHECKPOINT PROTEIN MAD2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11842:SF11">
        <property type="entry name" value="MITOTIC SPINDLE ASSEMBLY CHECKPOINT PROTEIN MAD2A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02301">
        <property type="entry name" value="HORMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56019">
        <property type="entry name" value="The spindle assembly checkpoint protein mad2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50815">
        <property type="entry name" value="HORMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="3" id="KW-0132">Cell division</keyword>
    <keyword evidence="4" id="KW-0498">Mitosis</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HORMA" evidence="7">
        <location>
            <begin position="1"/>
            <end position="166"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010348"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50815"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OBZ83779.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="179" mass="20230" checksum="80FF51B398F0050A" modified="2016-11-30" version="1">MEDFKLISKYGMKVYVSDNPELTSYVNKIIQQLQVWLVNNTISKLVIVIKSKDTLEVLERWSFDVNINGDNGLPMAENIPPEEAQIIQQNTVKQIRTILRQITASVSFLPELNSDDCGFNVLVYANKDVEVPLSWGDCGPNLIAGGGEHVRLKSFNTLVHKVDTFVAYKMDPSHFTDEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N586</accession>
    <name>A0A1C7N586_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_07686</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000534">
        <property type="protein sequence ID" value="OBZ84260.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N586"/>
    <dbReference type="InParanoid" id="A0A1C7N586"/>
    <dbReference type="OrthoDB" id="2284111at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ84260.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="136" mass="15443" checksum="AC21654D46306389" modified="2016-11-30" version="1">MAVFPNKTLKPTAIMSPRQTANKAYTLTIKKLDKDEKRCRPHYSIREKLLLSNTLAKAEQILNKQACLSRKSWVKQEDVLAPLPHYAPPSETKVQQWMSSIPEHMVLSIAVITFQQQPLSCRPISSFSLNSLTPII</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N5D7</accession>
    <name>A0A1C7N5D7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="2">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">PDPK2P</name>
        <name evidence="14" type="ORF">A0J61_07608</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PDPK1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="2"/>
    <dbReference type="EMBL" id="LUGH01000522">
        <property type="protein sequence ID" value="OBZ84342.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N5D7"/>
    <dbReference type="FunCoup" id="A0A1C7N5D7">
        <property type="interactions" value="385"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N5D7"/>
    <dbReference type="InParanoid" id="A0A1C7N5D7"/>
    <dbReference type="OrthoDB" id="347657at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035556">
        <property type="term" value="P:intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05581">
        <property type="entry name" value="STKc_PDK1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000191">
        <property type="entry name" value="3-phosphoinositide-dependent protein kinase 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000534">
        <property type="entry name" value="Serine/threonine-protein kinase PKH2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039046">
        <property type="entry name" value="PDPK1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050236">
        <property type="entry name" value="Ser_Thr_kinase_AGC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24356:SF163">
        <property type="entry name" value="3-PHOSPHOINOSITIDE-DEPENDENT PROTEIN KINASE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24356">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 14" id="KW-0418">Kinase</keyword>
    <keyword evidence="5 10 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 11" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="13">
        <location>
            <begin position="42"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="9"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="71"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="non-terminal residue" evidence="14">
        <location>
            <position position="352"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU000304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="OBZ84342.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="352" mass="40401" checksum="FB874DE94F770F4F" modified="2016-11-30" version="1" fragment="single">MVSLPTPPNLSTQINGCDPTLSTDVDDPSHPLHHHRRVVTDFDYGDILGEGSYSTVLVGRDKRTGKHYAVKRLDKAHIVKNNKVKYVMIERDALSRMNHPGIVKLYWTFKDNRSLYFVLDLAKSGELYTFIRRLAPFDLETTRFYAAEIFSAMSHIHSKGVIHRDIKPENILLDDNFHIKITDFGSAKILVEKEDHSEEEHTAARSFVGTAEYVSPELLRSDPVSKEADYWAFGCVIYQMLSGKSPFKAATDYLIFQKIKNLDYVVPDDFPETGKDIVQRLLTSEPETRLGVTGMEAIRDHPFFEDVDWDHLFQATPPNLREKLEEARQHPVTPPKFDLDNSEEEVEDMWFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N5F8</accession>
    <name>A0A1C7N5F8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">NAD-dependent protein deacetylase</fullName>
            <ecNumber evidence="6">2.3.1.286</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">Sirt2</name>
        <name evidence="13" type="ORF">A0J61_07620</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>N(6)-acetyl-L-lysyl-[protein] + NAD(+) + H2O = 2''-O-acetyl-ADP-D-ribose + nicotinamide + L-lysyl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:43636"/>
            <dbReference type="Rhea" id="RHEA-COMP:9752"/>
            <dbReference type="Rhea" id="RHEA-COMP:10731"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:17154"/>
            <dbReference type="ChEBI" id="CHEBI:29969"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:61930"/>
            <dbReference type="ChEBI" id="CHEBI:83767"/>
            <dbReference type="EC" id="2.3.1.286"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="9">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="9">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the sirtuin family. Class I subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.286" evidence="6"/>
    <dbReference type="EMBL" id="LUGH01000524">
        <property type="protein sequence ID" value="OBZ84330.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N5F8"/>
    <dbReference type="FunCoup" id="A0A1C7N5F8">
        <property type="interactions" value="285"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N5F8"/>
    <dbReference type="InParanoid" id="A0A1C7N5F8"/>
    <dbReference type="OrthoDB" id="420264at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0099115">
        <property type="term" value="C:chromosome, subtelomeric region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031934">
        <property type="term" value="C:mating-type region heterochromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005721">
        <property type="term" value="C:pericentric heterochromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033553">
        <property type="term" value="C:rDNA heterochromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046970">
        <property type="term" value="F:histone H4K16 deacetylase activity, NAD-dependent"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070403">
        <property type="term" value="F:NAD+ binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045950">
        <property type="term" value="P:negative regulation of mitotic recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031508">
        <property type="term" value="P:pericentric heterochromatin formation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000183">
        <property type="term" value="P:rDNA heterochromatin formation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd01408">
        <property type="entry name" value="SIRT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1600.10">
        <property type="entry name" value="SIR2/SIRT2 'Small Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1220">
        <property type="entry name" value="TPP-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029035">
        <property type="entry name" value="DHS-like_NAD/FAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050134">
        <property type="entry name" value="NAD-dep_sirtuin_deacylases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003000">
        <property type="entry name" value="Sirtuin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026591">
        <property type="entry name" value="Sirtuin_cat_small_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017328">
        <property type="entry name" value="Sirtuin_class_I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026590">
        <property type="entry name" value="Ssirtuin_cat_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11085:SF6">
        <property type="entry name" value="NAD-DEPENDENT PROTEIN DEACETYLASE SIRTUIN-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11085">
        <property type="entry name" value="NAD-DEPENDENT PROTEIN DEACYLASE SIRTUIN-5, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02146">
        <property type="entry name" value="SIR2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037938">
        <property type="entry name" value="SIR2_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52467">
        <property type="entry name" value="DHS-like NAD/FAD-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50305">
        <property type="entry name" value="SIRTUIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 6 8" id="KW-0520">NAD</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 6 9" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Deacetylase sirtuin-type" evidence="12">
        <location>
            <begin position="11"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="322"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="334"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="7 10">
        <location>
            <position position="133"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="39"/>
            <end position="43"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="49"/>
            <end position="51"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="113"/>
            <end position="116"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9 10">
        <location>
            <position position="141"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9 10">
        <location>
            <position position="144"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9 10">
        <location>
            <position position="165"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9 10">
        <location>
            <position position="168"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="205"/>
            <end position="206"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="229"/>
            <end position="231"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006924"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRNR" id="PIRNR037938"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR037938-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR037938-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR037938-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50305"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="OBZ84330.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="344" mass="38857" checksum="DB955803AF03FAAB" modified="2016-11-30" version="1">MPKTRQSSKKTALKDATIESIAKYIQENEVKNVIVMSGAGISTAAGIPDFRSKDTGLYHNLQKFDLPYAEAVFDIDYFKATKELYPGRFLPTKTHCFVRLLQEKGLLLRNFTQNIDTLERLTGLDPKYIVEAHGSFATASCIECKRKADPEKVKESALAAKISRCEDCDELIKPDIVFFGEGLPERFFDLIDDFEKADLLIVIGTSLQVQPFASLIDEVLDHVPRLLINRELAGVHHVKSSGFDFKWKYGLNRDAVYLGSCDGGVEKLCQLLGWEKDLSRLYTQCHKKLKAIWEAEQAQSKEEEPVVEQRQDEDVDHLAEVLEKLTADETPSSLEKEPSKKSPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N655</accession>
    <name>A0A1C7N655_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="11">CDK5 regulatory subunit-associated protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">Cdk5rap1</name>
        <name evidence="11" type="ORF">A0J61_07863</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the methylthiotransferase family. MiaB subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000557">
        <property type="protein sequence ID" value="OBZ84089.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N655"/>
    <dbReference type="STRING" id="101091.A0A1C7N655"/>
    <dbReference type="InParanoid" id="A0A1C7N655"/>
    <dbReference type="OrthoDB" id="190098at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035597">
        <property type="term" value="F:tRNA-2-methylthio-N(6)-dimethylallyladenosine(37) synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0060255">
        <property type="term" value="P:regulation of macromolecule metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0080090">
        <property type="term" value="P:regulation of primary metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.12160:FF:000003">
        <property type="entry name" value="CDK5 regulatory subunit-associated protein 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.80.30.20:FF:000003">
        <property type="entry name" value="CDK5 regulatory subunit-associated protein 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12160">
        <property type="entry name" value="Methylthiotransferase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.30.20">
        <property type="entry name" value="tm_1862 like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006638">
        <property type="entry name" value="Elp3/MiaA/NifB-like_rSAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005839">
        <property type="entry name" value="Methylthiotransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020612">
        <property type="entry name" value="Methylthiotransferase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013848">
        <property type="entry name" value="Methylthiotransferase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038135">
        <property type="entry name" value="Methylthiotransferase_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006463">
        <property type="entry name" value="MiaB_methiolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007197">
        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023404">
        <property type="entry name" value="rSAM_horseshoe"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058240">
        <property type="entry name" value="rSAM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002792">
        <property type="entry name" value="TRAM_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00089">
        <property type="entry name" value="MiaB/RimO family radical SAM methylthiotransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43020">
        <property type="entry name" value="CDK5 REGULATORY SUBUNIT-ASSOCIATED PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43020:SF2">
        <property type="entry name" value="MITOCHONDRIAL TRNA METHYLTHIOTRANSFERASE CDK5RAP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04055">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00919">
        <property type="entry name" value="UPF0004"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00273">
        <property type="entry name" value="(dimethylallyl)adenosine_tRNA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01082">
        <property type="entry name" value="B12-binding_domain_containing"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00413">
        <property type="entry name" value="CDK5RAP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01061">
        <property type="entry name" value="methylthiotransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00029">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00729">
        <property type="entry name" value="Elp3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102114">
        <property type="entry name" value="Radical SAM enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51449">
        <property type="entry name" value="MTTASE_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01278">
        <property type="entry name" value="MTTASE_RADICAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51918">
        <property type="entry name" value="RADICAL_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50926">
        <property type="entry name" value="TRAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="6" id="KW-0408">Iron</keyword>
    <keyword evidence="7" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <feature type="domain" description="MTTase N-terminal" evidence="9">
        <location>
            <begin position="79"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="domain" description="Radical SAM core" evidence="10">
        <location>
            <begin position="225"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="domain" description="TRAM" evidence="8">
        <location>
            <begin position="486"/>
            <end position="554"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="11">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009815"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51449"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="OBZ84089.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="566" mass="64142" checksum="7859BDA01E0860B2" modified="2016-11-30" version="1" fragment="single">QVGFLKHAQKTIRRHYAAAAVVALDETKKKKKRLVFDNRSPSFQDFLASQPTKPIDPSMAQPDQVPYLHTLSQNLGQGRKFFIEVYGCQMNVNDTEILNAIMTQTGFERTDQLEEANIVFLVTCAIRDNAEARIWDRLKYLRHYKTKINKESPPIIGVLGCMAERLKTKLLEEDRLVDIVCGPDGYRSIPHLISLAAEEEYTDGIANVMLSADETYADVMPMRLDTSNASGWVSIMRGCNNMCSFCIVPFTRGNERSRPIDSILDEVRYLNDQGVKEVTVLGQNVNSYRDESESKYFVTTDSLGSSLSNAGFKTIYKRKDGGRRFTELLDKVSLINPEMRIRFTSPHPKDFPTDLLHLIASRPNLCNSIHLPIQSGSNTVLERMRRGYTREAYLDLVQEMRKIIPDVWISSDFITGFCGETEQEHQDTVSLMEQVKYDTAYMFAYSMREKTHAHRRYKDDVEESVKARRLQEIVTTFHQQAAIKHQALIGSRQLVLIDSDRPKTKHGIETRVGGRTDGGHKVFVASSLDLKKGDYVEVEITHSTSASLVGRSLGLSSIQQFSSTVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N6B1</accession>
    <name>A0A1C7N6B1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="12">ATP-dependent bile acid permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">YBT1_1</name>
        <name evidence="12" type="ORF">A0J61_07267</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000482">
        <property type="protein sequence ID" value="OBZ84683.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N6B1"/>
    <dbReference type="InParanoid" id="A0A1C7N6B1"/>
    <dbReference type="OrthoDB" id="6500128at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000329">
        <property type="term" value="C:fungal-type vacuole membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd18596">
        <property type="entry name" value="ABC_6TM_VMR1_D1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18604">
        <property type="entry name" value="ABC_6TM_VMR1_D2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03250">
        <property type="entry name" value="ABCC_MRP_domain1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03244">
        <property type="entry name" value="ABCC_MRP_domain2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000565">
        <property type="entry name" value="ABC bile acid transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="entry name" value="ABC transporter type 1, transmembrane domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050173">
        <property type="entry name" value="ABC_transporter_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24223:SF353">
        <property type="entry name" value="ABC TRANSPORTER ATP-BINDING PROTEIN_PERMEASE VMR1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24223">
        <property type="entry name" value="ATP-BINDING CASSETTE SUB-FAMILY C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="ABC transporter transmembrane region"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="31"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="154"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="209"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="298"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="407"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="890"/>
            <end position="916"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="992"/>
            <end position="1012"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="1083"/>
            <end position="1104"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="11">
        <location>
            <begin position="174"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="10">
        <location>
            <begin position="499"/>
            <end position="742"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="11">
        <location>
            <begin position="809"/>
            <end position="1130"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="10">
        <location>
            <begin position="1171"/>
            <end position="1420"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="OBZ84683.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="1440" mass="161276" checksum="B7939E5F88165AB8" modified="2016-11-30" version="1">MKATALVNIASSFSASGKSLADIVCRHLNILYLIHFFISFINCYAYYSVFDFSIISQRYQLDIIDSGITFLLLILIVNETRNAPLKTIMADTGRETSSEKWVSIYSKFMFSWINGMMKKGSSQTLNDEDLIELIPENRTPNVLHKFRRHRKTTIALSILSAFKLPLFIQFCYCFVWSVLMFGPPYFLNRIIKYIEHCHDQDFHVPASTAFFYVLGLFLSSSIQSLSYQQALYIGRTLGIRVQSIIIGEVYNKSLKRRDESGSSTAKSTVDLAASKSAAKVKANINNLLSVDSQKMGEVMAYIFFFYCFPIQVIVCVWSLYALLGHASLWGVFVICVSQPLTYYLSKRFQGLHHEVMACTDRRIRLMTELLSAIRIIKFFAWEKQFRGRITKARDDELDKVRSRLYSFLWIGNVWFFIPVLIMIAVFYAYTHQYTLTASTAFTALALFNNFKSTLDELPFITTFILQANVSLGRIEKFLQEEEVQLPKQNFSSQTRIGFVDNANFSWYPSKEGSVAPVHLKNLNLSFPVNQLSIICGPTGSGKTTMIASLLGETYCLSGAAIIPKKDASSSCSSIGGAVSGVAYVAQTAWLQNCSIRDNILFGLPFDKDRYERVLYMTALTRDLDILEFGDSTEIGEKGITLSGGQKQRVAIARAVYSQADIVILDDCLSAVDAHTAKHLYQHCLIGDYMKHRTTILVTHHVALCIGGASYIVVLNDSGSVAANGAPLDVINTGVLGEDISQESLLLHSGAEEEAAVNGSILETPKAASTKMQINGAGKLVQEEKRAEGAVAKEVYYTYIQTTGGVLFWAAVILLFCSAQGSVLGQNYWIKIWSAAYNTTESNLVENNISIYHQMFLLNDATSQLFKINAVAPPSITEIIRQVRQRHTVDISYYLGIYFLIGLLSLALTTLNSLLLYHGSLKASKTIHNQLLDRILRAKIRFFDTTPMGRIINRFSSDLECIDQAVAPSLSALLFSVIATAYVIILVSAITPAFIVPGILIALIFRSIGTYYLETSRDMKRLNSVSRSPIYVQFNETVLGVATIRAFGCQERFIKENHNKIDCNNRPFLWMWATNRWLHCRVDILGGLVSFCTGVVLVISCNWVNPGLAGLSLSYALTFTRHVLWVVRMYAVNEMNMNAIERVCEYLDIEEEAPTHIPEACPPSSWPENGVVEINDLYMQYAQNTPAVLRGLSFKTRPREKIGIVGRTGSGKSTLGMSLFRFMEPTSGQICIDGVNICHVGLNDLRSRLTIIPQDPVLFTGTLRSNLDPFGQYDDAILWAALKRSHLINEPIRDMSAASHSDNSSASTSIITLDSAVTENGSNWSQGQRQLIALARALVKRTSLIVLDEATSSIDFDTDQQIQETIRKEFNNSTLLCIAHRIRTVADYDRILVLDHGQVKEFDSPYMLMKKEDSIFHQMCQRSGEFSELLAIAKAKHKKMY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N6G1</accession>
    <name>A0A1C7N6G1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Next to BRCA1 gene 1 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">NBR1</name>
        <name evidence="7" type="ORF">A0J61_07219</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000477">
        <property type="protein sequence ID" value="OBZ84722.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N6G1"/>
    <dbReference type="STRING" id="101091.A0A1C7N6G1"/>
    <dbReference type="InParanoid" id="A0A1C7N6G1"/>
    <dbReference type="OrthoDB" id="661148at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070013">
        <property type="term" value="C:intracellular organelle lumen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd14947">
        <property type="entry name" value="NBR1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd02249">
        <property type="entry name" value="ZZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd02340">
        <property type="entry name" value="ZZ_NBR1_like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.60.90:FF:000007">
        <property type="entry name" value="Next to BRCA1 gene 1 protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.60.90">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032350">
        <property type="entry name" value="Nbr1_FW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000433">
        <property type="entry name" value="Znf_ZZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043145">
        <property type="entry name" value="Znf_ZZ_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20930">
        <property type="entry name" value="OVARIAN CARCINOMA ANTIGEN CA125-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20930:SF0">
        <property type="entry name" value="PROTEIN ILRUN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16158">
        <property type="entry name" value="N_BRCA1_IG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00569">
        <property type="entry name" value="ZZ"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00291">
        <property type="entry name" value="ZnF_ZZ"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01357">
        <property type="entry name" value="ZF_ZZ_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50135">
        <property type="entry name" value="ZF_ZZ_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="ZZ-type" evidence="6">
        <location>
            <begin position="174"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="domain" description="ZZ-type" evidence="6">
        <location>
            <begin position="251"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="domain" description="ZZ-type" evidence="6">
        <location>
            <begin position="328"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="220"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="240"/>
            <end position="250"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00228"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OBZ84722.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="783" mass="88283" checksum="00042FD318C93BD4" modified="2016-11-30" version="1">MTVAFKVFYPKINEIRLIAINYGSAYFMWDALRKQVRSTFELDELFEFHFLFIDGTSDSIHLKTREEFQTFMNLYNQKYPPLTIVANSTQEAESQTMNTNQFDQSSHSNDPKILESLETFIKHLELGINDMQEKIEKNTTSAIDIIVKTAAETAAHVHRSLITSSKNSTSVKSMHDVICNGCYRPIRGQRYLCETCDDFDLCSACKSRVNHDATHNFRYIAPIDNNPPSPKMTEQHSSDESSCSTQSRSSQNRFFCDNCDSEIVGVRHACTSCPDFDLCSKCFYSVKYEHPDRHLFVTHVEGSQKMPEKTINKKAKKPSNDKARIIQHSGVECDSCDTPIEGIRYKCGNCPNYDLCEQCEEKASLIHDENHVFVKLRRPIQSVVHMPLLPELRFLDTATAETSNTPEIVSKPEEISYTNIPQKPLPITPEPLINASFISDLNIPEGTVIVPKKTFIKMWKVKNTGTVDWPIGSQLLFNGGSILRPYPISRPDCFAVPVVAPNEETCITAELQAPDSPGVYTSYFCICTPNGERFGDSLLCSIKVDEDLEPEKKPSSMPRTTSNTSLSNSHIMVYPTIDSYSETHDDVSHQDELSQKDLNPVYPEYDACSDATSGNHSSVVESQTTYTYTDSQVSSPTSLNLDMHDDYTDNEWNPETEGIYSVDDYHVISPARSPSPVFPEELPKQETSSPCFDEDEFIVLDNKQDEVIVEVEEMTTDASSLTNSSITATPDAGHPYQSQLLQLHEMVALNAVGFSSYDDLALSLLRFYEGEMERVVSKLLEYP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N6K6</accession>
    <name>A0A1C7N6K6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_07162</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000469">
        <property type="protein sequence ID" value="OBZ84785.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N6K6"/>
    <dbReference type="STRING" id="101091.A0A1C7N6K6"/>
    <dbReference type="InParanoid" id="A0A1C7N6K6"/>
    <dbReference type="OrthoDB" id="5586015at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042729">
        <property type="term" value="C:DASH complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072686">
        <property type="term" value="C:mitotic spindle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008608">
        <property type="term" value="P:attachment of spindle microtubules to kinetochore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013962">
        <property type="entry name" value="DASH_Dam1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08653">
        <property type="entry name" value="DASH_Dam1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="104"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="104"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="114"/>
            <end position="126"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ84785.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="258" mass="28972" checksum="9DCF8FA0C88023EB" modified="2016-11-30" version="1">MSTENSTIARLSSSIKSISHGFQRMTHNLENLSRVNDSLDAFNRSFGSFFLGMAINDTTIDWKKGPSDRDIELFKERKKQLASIEATKAVALLKESQVANTTAPHTVANSPAKSITPIRPSSTIPPQNRKRKPMDQRIIRTVKKRKPEPVPVETTSRPKHMAKINIKRTIDSLPLKFRESADPRANMEAVLKALRVHPSGLSFRDIAAVTNVPQHKVTDCVNALIHAKVVHRIEEESKASLFKLDPVKYPFHTVSQIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N7C2</accession>
    <name>A0A1C7N7C2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Protein NLRC3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">NLRC3_1</name>
        <name evidence="3" type="ORF">A0J61_06912</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000440">
        <property type="protein sequence ID" value="OBZ85040.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N7C2"/>
    <dbReference type="STRING" id="101091.A0A1C7N7C2"/>
    <dbReference type="InParanoid" id="A0A1C7N7C2"/>
    <dbReference type="OrthoDB" id="333024at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052201">
        <property type="entry name" value="LRR-containing_regulator"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24111:SF0">
        <property type="entry name" value="LEUCINE-RICH REPEAT-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24111">
        <property type="entry name" value="LEUCINE-RICH REPEAT-CONTAINING PROTEIN 34"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13516">
        <property type="entry name" value="LRR_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13855">
        <property type="entry name" value="LRR_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00368">
        <property type="entry name" value="LRR_RI"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="250"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="252"/>
            <end position="271"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ85040.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="475" mass="51791" checksum="8EE56A1519ABF60D" modified="2016-11-30" version="1">MAWGGNDGAVDRWVKQLEENDTKLVSLHILSFRRVTTADLARIFRAIGSNTVLKELYVSGHALDATCVDCLSEALTINDTLESLNLGNTHFGANSDVFGLFCEGLAANEGLIKLDLENKGLLTAAENKKYESVRLLAEALAKNKHLKELSVARNDLDDHAIELLAPALTGIQKVNLAINQVKSQGAHAISEHVLAPHSHVQELDLSDNPLLESACSLGKALAKNQTLRVLKLIDVVSNIEKDLSTLPPAALDSKDGKIEEADDKKKTDPLRSSHGNALMDTIGQALSTNTTLSSLCLDNNAIETNSLSKFIQHVPKSALTELKLRQNRIDDEGAERLATLSSLRYLELGENTISVKGFGALLNTQLEYLGLFNNRVGGFGADDVILPDLSSSKITRLDIGCNSIMHRDVKAMADILLKGGVPHLTLLEMGGNVEDKEIELWQETLDRVSEQRDQLEIVWKRKPTQMESAAPPPVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N864</accession>
    <name>A0A1C7N864_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Dienelactone hydrolase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_07106</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000463">
        <property type="protein sequence ID" value="OBZ84836.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N864"/>
    <dbReference type="FunCoup" id="A0A1C7N864">
        <property type="interactions" value="23"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N864"/>
    <dbReference type="InParanoid" id="A0A1C7N864"/>
    <dbReference type="OrthoDB" id="17560at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002925">
        <property type="entry name" value="Dienelactn_hydro"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47668:SF1">
        <property type="entry name" value="DIENELACTONE HYDROLASE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47668">
        <property type="entry name" value="DIENELACTONE HYDROLASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_6G01940)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01738">
        <property type="entry name" value="DLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Dienelactone hydrolase" evidence="1">
        <location>
            <begin position="30"/>
            <end position="238"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ84836.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="243" mass="27045" checksum="B3DD4016C50DDDCF" modified="2016-11-30" version="1">MSYSKACCKLPSVESNYSPVGTIETVDDLKVYTVGPKDAKKAVVVVYDIFGLHPNTKQFCDILAKNCGWKVVMPDFLRGDYWSFERGGMDALVAWIEKVGSIENVTPDVNRVQEQLKKDGVEAATLVGFCWGAKISVHLTSTHPFFVGASLIHPSFVDVKDAEAAQAPILALPSKDEPDMTEYMEVLSKKPFASLCKHVRFDDQPHGFCAARGNFEDETNVKRATEAIQLTVDFFHQCFNQKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N8D8</accession>
    <name>A0A1C7N8D8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Alanine--tRNA ligase</fullName>
            <ecNumber evidence="12">6.1.1.7</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12">Alanyl-tRNA synthetase</fullName>
            <shortName evidence="12">AlaRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="15" type="primary">malaS</name>
        <name evidence="12" type="synonym">ALA1</name>
        <name evidence="15" type="ORF">A0J61_06557</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged tRNA(Ala) via its editing domain.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11 12">
            <text>tRNA(Ala) + L-alanine + ATP = L-alanyl-tRNA(Ala) + AMP + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:12540"/>
            <dbReference type="Rhea" id="RHEA-COMP:9657"/>
            <dbReference type="Rhea" id="RHEA-COMP:9923"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57972"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78497"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.7"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="12">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="12">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="12">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="12">Mitochondrion</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="12">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="12">Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the class-II aminoacyl-tRNA synthetase family. Alax-L subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.7" evidence="12"/>
    <dbReference type="EMBL" id="LUGH01000401">
        <property type="protein sequence ID" value="OBZ85392.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N8D8"/>
    <dbReference type="STRING" id="101091.A0A1C7N8D8"/>
    <dbReference type="InParanoid" id="A0A1C7N8D8"/>
    <dbReference type="OrthoDB" id="2423964at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004813">
        <property type="term" value="F:alanine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002161">
        <property type="term" value="F:aminoacyl-tRNA deacylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070143">
        <property type="term" value="P:mitochondrial alanyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00673">
        <property type="entry name" value="AlaRS_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.930.10:FF:000011">
        <property type="entry name" value="Alanine--tRNA ligase, cytoplasmic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.980.10:FF:000004">
        <property type="entry name" value="Alanine--tRNA ligase, cytoplasmic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.310.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.54.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="entry name" value="Bira Bifunctional Protein, Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.980.10">
        <property type="entry name" value="Threonyl-trna Synthetase, Chain A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00036_B">
        <property type="entry name" value="Ala_tRNA_synth_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002318">
        <property type="entry name" value="Ala-tRNA-lgiase_IIc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018162">
        <property type="entry name" value="Ala-tRNA-ligase_IIc_anticod-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018165">
        <property type="entry name" value="Ala-tRNA-synth_IIc_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018164">
        <property type="entry name" value="Ala-tRNA-synth_IIc_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050058">
        <property type="entry name" value="Ala-tRNA_ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023033">
        <property type="entry name" value="Ala_tRNA_ligase_euk/bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003156">
        <property type="entry name" value="DHHA1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018163">
        <property type="entry name" value="Thr/Ala-tRNA-synth_IIc_edit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012947">
        <property type="entry name" value="tRNA_SAD"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00344">
        <property type="entry name" value="alaS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11777:SF9">
        <property type="entry name" value="ALANINE--TRNA LIGASE, CYTOPLASMIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11777">
        <property type="entry name" value="ALANYL-TRNA SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02272">
        <property type="entry name" value="DHHA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01411">
        <property type="entry name" value="tRNA-synt_2c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07973">
        <property type="entry name" value="tRNA_SAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00980">
        <property type="entry name" value="TRNASYNTHALA"/>
    </dbReference>
    <dbReference type="SMART" id="SM00863">
        <property type="entry name" value="tRNA_SAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="Class II aaRS and biotin synthetases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101353">
        <property type="entry name" value="Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55186">
        <property type="entry name" value="ThrRS/AlaRS common domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="Translation proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50860">
        <property type="entry name" value="AA_TRNA_LIGASE_II_ALA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 12" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="7 12" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="13" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="12" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 12 15" id="KW-0436">Ligase</keyword>
    <keyword evidence="4 12" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5 12" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9 12" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 12" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="2 12" id="KW-0820">tRNA-binding</keyword>
    <keyword evidence="6 12" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Alanyl-transfer RNA synthetases family profile" evidence="14">
        <location>
            <begin position="27"/>
            <end position="746"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="13">
        <location>
            <begin position="760"/>
            <end position="797"/>
        </location>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="600"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="604"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="703"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="707"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00048300"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50860"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="OBZ85392.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="912" mass="102930" checksum="AFDC32BB0DBEFDCA" modified="2016-11-30" version="1">MYRAQRWFRETTIPKSQLLQTRWMRQLTSRELRSTFIDYFEKQGHTAVKSASLVPHQDKTLLFTNAGMVPFKEFFLKPKSAPFQSATSIQKCMRAGGKHNDLDNVGYTPRHHTFFEMLGNFSFGRYSKAEAIDYAWKFLLKELELPIHRLRVTVLEGDKEAYDLWKQQGLPDDRIVTCGPEDNFWSMGDGEGPCGSCTEIFWDTQDASLEDPWLEIWNLVFMEKYRTAEGVLTDLPIPCIDTGMGLERMISVLQEKKNNFQIDQFQTLIGGLRQVMQKRGLTASSAVDPSAQEKIITDHFRAMCFLIGDGVVPSNVGRGYVLRRIIRRALRAAKQLGFNEPFLSELYPSLLAGFDHDEYPELASRASSIQSIIMNEETAFLATLDRGMQVLENVFNQADLQTSKQIPPQVAFQLYDTFGFPFDLTLIIAHERGWTIDIEAVEALREKQRQAGKESWKSSDITDKSRLSEWRQLNIKPQFTGYDRALFNQESEILAIDSVQKKNGKTEVTIAIDPCPFYGLGGGQVPDQGTITLTNGHIWQVNDVMIPYEGGLALRIQPLGLGANETVMDRLLEDQACLQQGQLVRTDIDVKRREGAEVHHTATHLLNAGLRQVLGSTDIVQAGSTVEPRKLRFDFTYGKPLKPKELDQIEDWINQAALVGGKTEVRQMRLTDAVNEGAIAAFSEKYGEVVRVIDVPGVTKELCGGTHVTDIKKIYPFKILNETSVAAGTRRIEAVAGLACIDWYRKTYEPVPEALRLLRANNTNEMIDKLEKTMQQTKELQKRLEFMNEKLASADKVIQKPIETKVKDMEVKVHLIDQDLDASFMQKRANVLKEIQPSSVHVLVNKNTIVVALNSTEIKHQTADSVLKQLLKSMKGGGGGQKEMAQGRLAQPIMNQADIESKVLPALQKIQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N8N6</accession>
    <name>A0A1C7N8N6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_06484</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000393">
        <property type="protein sequence ID" value="OBZ85463.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N8N6"/>
    <dbReference type="STRING" id="101091.A0A1C7N8N6"/>
    <dbReference type="InParanoid" id="A0A1C7N8N6"/>
    <dbReference type="OrthoDB" id="2125396at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019005">
        <property type="term" value="C:SCF ubiquitin ligase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031146">
        <property type="term" value="P:SCF-dependent proteasomal ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13318">
        <property type="entry name" value="PARTNER OF PAIRED, ISOFORM B-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12937">
        <property type="entry name" value="F-box-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="2">
        <location>
            <begin position="13"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="104"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="283"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="107"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="283"/>
            <end position="320"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12937"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ85463.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="433" mass="49340" checksum="434F444F407557DA" modified="2016-11-30" version="1">MPLVTREKNAFPLPPELLLEVLSYLNHSQTSLHAASLVCKEWLFCATPILYGHPKILDTYRWATFILTLTRQRMSFFYGHLVRSIDLSSGKSIDTKKDQEFYRRLSDTASNSDSTEAGSSSTQARNVTITITRNQIIVEDNQTETEHDFVVKGLPYIIVSTSSLIQVASTCKNITHLNLSSTSLLHDSQVVETGEYLSTLQHFVQPGLTQVQISIETAIESIGRECKRLTHIKIQRCEWVTAHVIWMFAYYCPYLQQLDARRSFKCTVKRLINNVLEASHTIPTSTTNTTIPPPTSSSSSSSPSSSSSHSYASSSSSSPTHWRRHPPDIINSFLSTDRMYSNYHHHMHYNLNRNQVHQRRLGEYSTEGDEEEPHYHRLEDELYERLENLMETSQTMGRHAGKTLKNLVYDILLDAKDLGAVDLNWLQQYVGPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N919</accession>
    <name>A0A1C7N919_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_06327</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000377">
        <property type="protein sequence ID" value="OBZ85625.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N919"/>
    <dbReference type="InParanoid" id="A0A1C7N919"/>
    <dbReference type="OrthoDB" id="2284403at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="84"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="110"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="119"/>
            <end position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ85625.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="267" mass="29528" checksum="FD965C53AFCAEEC4" modified="2016-11-30" version="1">MMTNTPTAMAHPRPTTISKSISSAIHSKPTHISEQKAPTPNIVQSAVYQKEPSEFSRMDAIQASLVPTKPSSKSNYGTLSTASIVAPIVSVCGGIVLIAAAMFFIVATKRKRGRRRRRQSQENREYNDRDDEDRFHDVSLSDDEDNSRIMHAKSTRLTATEKPPLPPMPPLSSRTSSITLTSHARPKSTGSFSTTSTIYADALSSPMGSIKCPKTPVLKIAERQQLSHQRPSIIQTYRAQLSNSVILPETQDSQDPILPFQYYTCIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N992</accession>
    <name>A0A1C7N992_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Nucleolin 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">NUCL2</name>
        <name evidence="6" type="ORF">A0J61_06291</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000373">
        <property type="protein sequence ID" value="OBZ85660.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N992"/>
    <dbReference type="STRING" id="101091.A0A1C7N992"/>
    <dbReference type="InParanoid" id="A0A1C7N992"/>
    <dbReference type="OrthoDB" id="439808at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00590">
        <property type="entry name" value="RRM_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23236">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 4B/4H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23236:SF119">
        <property type="entry name" value="NUCLEAR RNA-BINDING PROTEIN SART-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 3" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="5">
        <location>
            <begin position="100"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="5">
        <location>
            <begin position="193"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="266"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="17"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="56"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="266"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="4">
        <location>
            <begin position="286"/>
            <end position="343"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OBZ85660.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="343" mass="37600" checksum="8BE2A7F781E733B6" modified="2016-11-30" version="1">MAPSEVQEKHILEKKEKKEKKEKKEKKDKKEKKEKKEKKEKKEKKAKVEEEEVEATEEKVEEHIEESASDSEASGTKRKAEEEQEEAAPAKFTKTEQSVFTVWCGGISYEATADDIKSFFEQCGEITDVRIRMDDSTGKNKGFCHIDFATKEAQDAALQLSNSEFMGRYIRLDAADGATRQRAKDENYGGKTNKVFVANLNRDYDEAAHREALTEAFSKFGTIVSDIRLPYKRDEEGVLKGIAYVEFETVEQAEAAVTGMNGVDINERPIRTDFSGSDDRDRAGRGGRGGRGGGRGGFGGRGGGRGGFGGRGGGRGGFGGRDNFGGRGGGRGGRGGFRGRGGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N9F9</accession>
    <name>A0A1C7N9F9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">A0J61_06221</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000366">
        <property type="protein sequence ID" value="OBZ85727.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N9F9"/>
    <dbReference type="STRING" id="101091.A0A1C7N9F9"/>
    <dbReference type="InParanoid" id="A0A1C7N9F9"/>
    <dbReference type="OrthoDB" id="6365676at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000125">
        <property type="entry name" value="Putative zinc finger protein 143"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000072">
        <property type="entry name" value="zinc finger protein 143 isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:002343">
        <property type="entry name" value="Zinc finger protein 33A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23235">
        <property type="entry name" value="KRUEPPEL-LIKE TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23235:SF60">
        <property type="entry name" value="STRIPE, ISOFORM D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="7">
        <location>
            <begin position="79"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="7">
        <location>
            <begin position="109"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="7">
        <location>
            <begin position="316"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="7">
        <location>
            <begin position="346"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="47"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="137"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="361"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="47"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="66"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="367"/>
            <end position="385"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OBZ85727.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="385" mass="44174" checksum="0356446D1579897F" modified="2016-11-30" version="1">MESQQQQTTFAYSTERLPSINMLKTPCYTPSNDYPFNRNQSIVVSPPLTPLVSPSASSLTSPNQPKNKKSKVQNQQHKHVCHFQFCGWSFKRYEHLKRHMLVHTGERPYNCHFPNCGKSFSRSDNFHAHYRTHTKVKNSTRRKKGDTKPSVTMEDNQSNNTFSLLAGYPNTKSQQQKIIMTSNCSVASTVATHAAATAVAASQHFVPNTLYYNSHLYDHQRQHASSEIMNFTRNHTTAFQSCGMLNFEIQRTSPPISPVSSATSLSLLSHEISTPETYQHLPSPHSMYAFPYSSFPSADIHYSIVKSDKSSHVKPHVCSVPQCLRRFKRLEHLKRHMRIHTLERPFVCSYPDCQKRFSRSDNLAQHAKTHQKHEEKKRKKSIITK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NA12</accession>
    <name>A0A1C7NA12_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_05998</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000342">
        <property type="protein sequence ID" value="OBZ85965.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NA12"/>
    <dbReference type="InParanoid" id="A0A1C7NA12"/>
    <dbReference type="OrthoDB" id="2131431at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="39"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="87"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="119"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="160"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="202"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="248"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="287"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="423"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="433"/>
            <end position="448"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ85965.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="458" mass="50855" checksum="9B2ABBB273E06C20" modified="2016-11-30" version="1">MNHSAYDLETLSRVCLDGVCHCDWRLTIRDCAESEAMTIVYGIHAGLSGMNFLIGSALLFNRVILKGHTLFDASASKGCFRPKPIDCMLLFLIIFNLLRLILSIVLLTDICPDMISRSFLYEFAWQFEYGGFAVYLIGIAQTLADSHRAIANSWLPSPRLVDIIGGTLFTAPFIINNVMSLAAGILAESNLHLAQLFTRLLYIMWFVHCSVLSCLVAYAGVKLVAILREHLQKFNTSGPRYIAIQTGIFKIRAVVTIISIAVMMFAVFLLIFGILREIIVINYAGSIVLGIVWNFLGAFSSGGVIIAVLVNPKIDDNTNLGLKTSSAEKSNSQQTPQFVTYSNFSAQEYSATTSTNNHGTPGTLSHNAFDELKLQQLQYQKVFQKHNQVPHSAIDKKPVPEMKVSASGIPLQDSDYYNVEEKHSFRGNHHQAHHVDDDPIVDDGEHSQMDLVEYASKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NA56</accession>
    <name>A0A1C7NA56_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Zinc transporter 4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">Slc30a4</name>
        <name evidence="12" type="ORF">A0J61_05939</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000337">
        <property type="protein sequence ID" value="OBZ86012.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NA56"/>
    <dbReference type="STRING" id="101091.A0A1C7NA56"/>
    <dbReference type="InParanoid" id="A0A1C7NA56"/>
    <dbReference type="OrthoDB" id="9944568at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005385">
        <property type="term" value="F:zinc ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098771">
        <property type="term" value="P:inorganic ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030003">
        <property type="term" value="P:intracellular monoatomic cation homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1510.10">
        <property type="entry name" value="Cation efflux protein transmembrane domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002524">
        <property type="entry name" value="Cation_efflux"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027470">
        <property type="entry name" value="Cation_efflux_CTD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036837">
        <property type="entry name" value="Cation_efflux_CTD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058533">
        <property type="entry name" value="Cation_efflux_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027469">
        <property type="entry name" value="Cation_efflux_TMD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050681">
        <property type="entry name" value="CDF/SLC30A"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01297">
        <property type="entry name" value="CDF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11562">
        <property type="entry name" value="CATION EFFLUX PROTEIN/ ZINC TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11562:SF17">
        <property type="entry name" value="RE54080P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01545">
        <property type="entry name" value="Cation_efflux"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16916">
        <property type="entry name" value="ZT_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160240">
        <property type="entry name" value="Cation efflux protein cytoplasmic domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161111">
        <property type="entry name" value="Cation efflux protein transmembrane domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0406">Ion transport</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="5" id="KW-0864">Zinc transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="52"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="85"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="114"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="152"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="213"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="242"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="domain" description="Cation efflux protein transmembrane" evidence="10">
        <location>
            <begin position="52"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="domain" description="Cation efflux protein cytoplasmic" evidence="11">
        <location>
            <begin position="281"/>
            <end position="350"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008873"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF01545"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF16916"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="OBZ86012.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="365" mass="39822" checksum="CA718211822DDB13" modified="2016-11-30" version="1">MTDTEREPLLSTPVYTQTNSGGSVVSYTIAQQNCSNRAIKDRSTADSTKKKLWFAVALACCFFATELVAGYFANSLALMSDAFHLLSDVASFIVALVAIYLAEKPATKKHTFGFHRAEVIAALISVLTIWILTAFLVNEAFQRIKNPQVIDAKLMCITASIGVIVNIVLAYVLGGHHHGHSHDNENTIESQGATDTDAAHTHHKETNINLRAAALHVIGDLLASIGVLISSVILIFKPELTIVDPLCTFLFSILVLYTTYHLVKDSLAVLMEGVPGNIHPDLIEQSLLTVPGVLAVHDLHVWTLSPGKYSLTAHIKIDSQRSDYDEVLAKGQHIVCDIYGVHHSTLQIETDNTPFTSHCNPTMCS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NA90</accession>
    <name>A0A1C7NA90_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_05898</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000333">
        <property type="protein sequence ID" value="OBZ86052.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NA90"/>
    <dbReference type="InParanoid" id="A0A1C7NA90"/>
    <dbReference type="OrthoDB" id="2250794at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="140"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="14"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="238"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="385"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="153"/>
            <end position="163"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ86052.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="438" mass="51396" checksum="071A83D75E8C1DBB" modified="2016-11-30" version="1">MDQKHRYHTSKVRNEHHLLDIIQLEQEIAHVQQQIDNKRRSTRDLQQKKLDYQHRIQLHQKYQTCLQPKSKEVGRHDLSQLLTVSADTVCTKLQAYIERQLSAGQPLSSLELTQIQHWVKRLSNPSLDEVIDQLLTQIQQQRPQEQDKERPLQPTQLSHPKQDQVSLLVNELSQLEKETASVEAKLIQRIRATHQDHSIQSALSKNLRMKAACLQAKTELEFNRKQLAALDIQLTKSNVALSSETKRLKEQTDQLLEQLAEKHKQIQTFIKLNQRFQDTFRTNHDQHHNESESVTKRIRESMEALKCPTSSLKKSHDPSPLDAIKKELVPSIKISDTQMMIEIKQLIDSVNQLSQYIHKDNSDQEELTEMIKRWSQSVKMDLRPQDTAIQSIDRLREHIEKKEQEYIRQQEAILREKLKTTESIEKELVKTEQALNER</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NAZ5</accession>
    <name>A0A1C7NAZ5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Pre-mRNA-splicing factor ATP-dependent RNA helicase prp22</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">prp22_0</name>
        <name evidence="9" type="ORF">A0J61_05664</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5 11">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.13"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000313">
        <property type="protein sequence ID" value="OBZ86277.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NAZ5"/>
    <dbReference type="STRING" id="101091.A0A1C7NAZ5"/>
    <dbReference type="InParanoid" id="A0A1C7NAZ5"/>
    <dbReference type="OrthoDB" id="10253254at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071013">
        <property type="term" value="C:catalytic step 2 spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000390">
        <property type="term" value="P:spliceosomal complex disassembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd17971">
        <property type="entry name" value="DEXHc_DHX8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd21691">
        <property type="entry name" value="GH2-like_DHX8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd05684">
        <property type="entry name" value="S1_DHX8_helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18791">
        <property type="entry name" value="SF2_C_RHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.140:FF:000061">
        <property type="entry name" value="ATP-dependent RNA helicase DHX8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000191">
        <property type="entry name" value="Pre-mRNA-splicing factor ATP-dependent RNA helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:002859">
        <property type="entry name" value="putative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16 isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044762">
        <property type="entry name" value="DHX8/Prp22_DEXHc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049588">
        <property type="entry name" value="DHX8_GH2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002464">
        <property type="entry name" value="DNA/RNA_helicase_DEAH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049621">
        <property type="entry name" value="S1_DHX8_helicase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003029">
        <property type="entry name" value="S1_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18934">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18934:SF85">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE DHX8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00575">
        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00316">
        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00690">
        <property type="entry name" value="DEAH_ATP_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50126">
        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 9" id="KW-0347">Helicase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="4" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="3 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="S1 motif" evidence="7">
        <location>
            <begin position="177"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="8">
        <location>
            <begin position="483"/>
            <end position="646"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="124"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="141"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="740"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00047984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OBZ86277.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="740" mass="83504" checksum="8945590E0F186605" modified="2016-11-30" version="1" fragment="single">MDDIEKLEHLSLVQKVASELYNHTGLHEQVLAEFIIHLHDQANGSLAKFKSSLKEAAADFPDSFVENLDRLIKTLKPKKQTVHRQEDVDEKTSIFPGLAVKDDPNWQKKREEDMEVADDMLAELEGLKTKRKPSRSPSPPPRRHRRSRSPSPRHRSPRRRHSPPSSRRTLDDRPIIYKIYHGTVTNIKDFGAFVRLEGIRGKAEGLVHVGSLVQGRVNHPREVVKPKQLVRVKVMSVTNDRIGLSMKDVDQRTGEDLSPNLRVRSREEMEAMASRNPDRHTYLEDSSTVRMDDSMPSRSVQRMSSPERWELKQLIASGVVDPADYPELNEDNDFSNSNAVEAEEEIDVEVREEEPPFLKGQTSQTLDLSPVKVVKIPDGTLNRSALAGASLAKERRELRQQQIQQEMDAVPQDVNTPWLDPMAGPAGRQFAQDARGMPTKSDQIPEWKKATFNNATTFGKVTNLTIQEQRESLPIYKLRTSLIEAVRENQMLIVVGDTGSGKTTQMTQYLAEEGFANYGRIGCTQPRRVAAMSVAKRVAEEVGCRVGQEVGYTIRFEDCTSPETRIKYMTDGMLLRECLIDPEMSQYSVIILDEAHERTISTDVLFGLLKRAAKRRPDLKLIITSATLDADKFATYFNNCPIFTIPGRTYPVEVLYTKDPESDYLDAALITVMQIHLSEPPGDILLFLTGQEEIDTASEILFERMKALGNDVPELIILPVYSALPSEMQSRIFDPAPPGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NB72</accession>
    <name>A0A1C7NB72_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_05571</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000304">
        <property type="protein sequence ID" value="OBZ86375.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NB72"/>
    <dbReference type="InParanoid" id="A0A1C7NB72"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ86375.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="270" mass="31293" checksum="E486C1689B08AD29" modified="2016-11-30" version="1">MVKDFVSALVSSTSLGRSQNDLYDNLVALVQQAPYIASVTFDCEYKKILLEAIRNTCDADHKKRLQVKLVSSEYISYELYSEETPASQMSLEDINVEFLSDKQLTVGLTDCFSLNIENLFRRMEVDEVDRIVHQYPQSIALKLSVFRLTDWNKVLNETEFYLNVTQLTVYSILPTNVLLQYIYSKFLNVQHFELIEPYKFIQTDNFMPLETITRFAYYLDNMNEFKIALYRLTSSIDVESYFRSVITPTSTSIQSSNGGLELTFLRPKPT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NBP2</accession>
    <name>A0A1C7NBP2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">PAS domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_05422</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000291">
        <property type="protein sequence ID" value="OBZ86537.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NBP2"/>
    <dbReference type="STRING" id="101091.A0A1C7NBP2"/>
    <dbReference type="InParanoid" id="A0A1C7NBP2"/>
    <dbReference type="OrthoDB" id="411251at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.20">
        <property type="entry name" value="PAS domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013655">
        <property type="entry name" value="PAS_fold_3"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00229">
        <property type="entry name" value="sensory_box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08447">
        <property type="entry name" value="PAS_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00091">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="PYP-like sensor domain (PAS domain)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50112">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PAS" evidence="1">
        <location>
            <begin position="1"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="domain" description="PAS" evidence="1">
        <location>
            <begin position="176"/>
            <end position="222"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ86537.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="265" mass="30129" checksum="1B68D4B24A071196" modified="2016-11-30" version="1">MEINYITIYDNTPEAKVLFVSESVTDVLGWQPEDLLGHGGYAITHPDERHALALIHSTNVKNERMSSVTSYRSRHKKGHYINTDVVIHYCYDVLIATHFAVVSTDCIKHKFRTSSADEAYVIQPDGTIQLTGAWNDSQQRIKTLLTNKNPWMEVTDQTREPRFCLFLNRYSNQNIIVFATKMSASLVGLDPFDCIGQSLLNYIDPKDRESVSKQIQLSKSNDMVTRMRFQWVTPQETLVPVEAVCSCTYDGLVIVVRSMPMAITT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NC13</accession>
    <name>A0A1C7NC13_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">SAM50-like protein SPAC17C9.06</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">A0J61_05273</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion outer membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SAM50/omp85 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000281">
        <property type="protein sequence ID" value="OBZ86667.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NC13"/>
    <dbReference type="STRING" id="101091.A0A1C7NC13"/>
    <dbReference type="InParanoid" id="A0A1C7NC13"/>
    <dbReference type="OrthoDB" id="1724197at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005741">
        <property type="term" value="C:mitochondrial outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045040">
        <property type="term" value="P:protein insertion into mitochondrial outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.160.50">
        <property type="entry name" value="membrane protein fhac: a member of the omp85/tpsb transporter family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000184">
        <property type="entry name" value="Bac_surfAg_D15"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039910">
        <property type="entry name" value="D15-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12815:SF18">
        <property type="entry name" value="SORTING AND ASSEMBLY MACHINERY COMPONENT 50 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12815">
        <property type="entry name" value="SORTING AND ASSEMBLY MACHINERY SAMM50 PROTEIN FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01103">
        <property type="entry name" value="Omp85"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1134">Transmembrane beta strand</keyword>
    <feature type="domain" description="Bacterial surface antigen (D15)" evidence="6">
        <location>
            <begin position="122"/>
            <end position="436"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004374"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022452"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OBZ86667.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="437" mass="47233" checksum="F350D9F78699BB3F" modified="2016-11-30" version="1">MSNTTETPLPKNVPAEAPLRVNTLRILGTNVTRHSFLNSVTNTVFGANTTEEVMQQVQAMANQLQKHDIFEEIKVYLDTNREVTDTVDVTLHLKEKDKGLFETNINVGNNQAELNGGVGLRNVFGGAESLLASFSFGNRTRAAVEGAFETPFRGSASAKVGLFVNGSIRDHSQINAFKESSKTTGIRFKGLTTFGRHELAYAVTHKDLLALSKASSLVRTHSGDHKKHAVLHSFIRDHRDSVTLPTEGHYIGIFQELAGLGGKGDASFLKHELNASVHQPLTSDKLVVFSSSVRAGLISTMNEPKEIPLTDRFYLGGPLSVRGFKMGGIGEREGNDAVGGEAYWAAGASLVARLPGLDHVKAHAFANAGSIVTQAQGVPLGETIKTLSETSRSSVGFGLIFHHPIARIEANYCIPVRYSATDLPEPKLQFGFGVNFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NCA3</accession>
    <name>A0A1C7NCA3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Leupaxin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">LPXN</name>
        <name evidence="7" type="ORF">A0J61_05203</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000275">
        <property type="protein sequence ID" value="OBZ86742.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NCA3"/>
    <dbReference type="STRING" id="101091.A0A1C7NCA3"/>
    <dbReference type="InParanoid" id="A0A1C7NCA3"/>
    <dbReference type="OrthoDB" id="1112565at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003712">
        <property type="term" value="F:transcription coregulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd08368">
        <property type="entry name" value="LIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.110.10">
        <property type="entry name" value="Cysteine Rich Protein"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001781">
        <property type="entry name" value="Znf_LIM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24205">
        <property type="entry name" value="FOUR AND A HALF LIM DOMAINS PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24205:SF16">
        <property type="entry name" value="GH01042P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00412">
        <property type="entry name" value="LIM"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00132">
        <property type="entry name" value="LIM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57716">
        <property type="entry name" value="Glucocorticoid receptor-like (DNA-binding domain)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50023">
        <property type="entry name" value="LIM_DOMAIN_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0440">LIM domain</keyword>
    <keyword evidence="1 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 5" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="LIM zinc-binding" evidence="6">
        <location>
            <begin position="88"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="domain" description="LIM zinc-binding" evidence="6">
        <location>
            <begin position="181"/>
            <end position="256"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023038"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OBZ86742.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="286" mass="33177" checksum="5B1A5E2D1D13B6D5" modified="2016-11-30" version="1">MVTVGKPSLVECPLCQSSMRIQQLASHVCLYSQPAYRFSQVSHYETDHPPSFQDIYLPTKQTRVTSPLLSLTQIIEKKKAELKRWASNRKNRCSRCFRYDAPIHMAEKYYHAKCFSCFYCRTPLLSSNARLIPRVHQGQIYCSQHYPIAVNQPTCASCHCTIPSSVRPTMALGHYFHPEHLRCHHCRKPVDPFMTGIREAKVEKEAVVSRDGKLKGKWHKQCFRCQACHVQFPDNQFYIYNNQPYCKLDYHKLNNTLCHSCSLPVEGECAVTSEGWRFHPDCFVCH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NCC8</accession>
    <name>A0A1C7NCC8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Acyl-CoA desaturase</fullName>
            <ecNumber evidence="14">1.14.19.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="primary">OLE1_1</name>
        <name evidence="17" type="ORF">A0J61_06949</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="14">Stearoyl-CoA desaturase that utilizes O(2) and electrons from reduced cytochrome b5 to introduce the first double bond into saturated fatty acyl-CoA substrates.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>octadecanoyl-CoA + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) = (9Z)-octadecenoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O</text>
            <dbReference type="Rhea" id="RHEA:19721"/>
            <dbReference type="Rhea" id="RHEA-COMP:10438"/>
            <dbReference type="Rhea" id="RHEA-COMP:10439"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
            <dbReference type="ChEBI" id="CHEBI:29034"/>
            <dbReference type="ChEBI" id="CHEBI:57387"/>
            <dbReference type="ChEBI" id="CHEBI:57394"/>
            <dbReference type="EC" id="1.14.19.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="14">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
        <text evidence="14">Expected to bind 2 Fe(2+) ions per subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 14">Belongs to the fatty acid desaturase type 1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.14.19.1" evidence="14"/>
    <dbReference type="EMBL" id="LUGH01000444">
        <property type="protein sequence ID" value="OBZ85004.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NCC8"/>
    <dbReference type="FunCoup" id="A0A1C7NCC8">
        <property type="interactions" value="231"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NCC8"/>
    <dbReference type="InParanoid" id="A0A1C7NCC8"/>
    <dbReference type="OrthoDB" id="10260134at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004768">
        <property type="term" value="F:stearoyl-CoA 9-desaturase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006636">
        <property type="term" value="P:unsaturated fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03505">
        <property type="entry name" value="Delta9-FADS-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.120.10">
        <property type="entry name" value="Cytochrome b5-like heme/steroid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009160">
        <property type="entry name" value="Acyl-CoA_deSatase_haem/ster-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015876">
        <property type="entry name" value="Acyl-CoA_DS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001199">
        <property type="entry name" value="Cyt_B5-like_heme/steroid-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036400">
        <property type="entry name" value="Cyt_B5-like_heme/steroid_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018506">
        <property type="entry name" value="Cyt_B5_heme-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005804">
        <property type="entry name" value="FA_desaturase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001522">
        <property type="entry name" value="FADS-1_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11351">
        <property type="entry name" value="ACYL-COA DESATURASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11351:SF31">
        <property type="entry name" value="DESATURASE 1, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00173">
        <property type="entry name" value="Cyt-b5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00487">
        <property type="entry name" value="FA_desaturase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000345">
        <property type="entry name" value="OLE1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00363">
        <property type="entry name" value="CYTOCHROMEB5"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00075">
        <property type="entry name" value="FACDDSATRASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM01117">
        <property type="entry name" value="Cyt-b5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55856">
        <property type="entry name" value="Cytochrome b5-like heme/steroid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00191">
        <property type="entry name" value="CYTOCHROME_B5_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50255">
        <property type="entry name" value="CYTOCHROME_B5_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00476">
        <property type="entry name" value="FATTY_ACID_DESATUR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="14" id="KW-0249">Electron transport</keyword>
    <keyword evidence="13 14" id="KW-0275">Fatty acid biosynthesis</keyword>
    <keyword evidence="7 14" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="4 14" id="KW-0349">Heme</keyword>
    <keyword evidence="10 14" id="KW-0408">Iron</keyword>
    <keyword evidence="3 14" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="11 14" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="12 15" id="KW-0472">Membrane</keyword>
    <keyword evidence="6 14" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9 14" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 15" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 15" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="14" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="43"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="73"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="104"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="186"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="domain" description="Cytochrome b5 heme-binding" evidence="16">
        <location>
            <begin position="340"/>
            <end position="419"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PIRNR" id="PIRNR000345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="OBZ85004.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="452" mass="51906" checksum="A4333F74E24014DD" modified="2016-11-30" version="1">MSNVQTITSIERTKTESMKPPLPKTKMPPLFDQPVTSKNWTKFVNWPQSILLISTPLIGLYGAFTTTLTKNTLIWAIIYYFITGLGITAGYHRMWAHRAYRGTLLLRWFFSFAGAGAVEGSAYWWSRGHRAHHRWTDTDKDPYSAHRGFFFSHFGWMLVQRPRSRIGYADVADLKADSTVAFQHKYYPYFALGMGFIFPTLVAGLGWGDFRGGFFYAGVLRLVFVHHATFCVNSLAHYLGETTFDDHNTPRDSWVTAFVTLGEGYHNFHHQFPQDYRNAIKYHQYDPTKWLIIVLSWFGLAYELKQFPSNEVTKGLLFMQEKKIQEQKSKLNYGTPLKDLPIYTWDEFQNLVVNENKKWVLIEGVLYDVAEFMKEHPGGMKYLSTAIGKDMTTSFNGGIYNHSNGARNLLTSLRVGVLLNGMQVMSEADATANAYDDSLEFDTKSAQFYKNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NCW9</accession>
    <name>A0A1C7NCW9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="9">SH3 domain-containing kinase-binding protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">SH3KBP1_0</name>
        <name evidence="9" type="ORF">A0J61_05155</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000271">
        <property type="protein sequence ID" value="OBZ86800.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NCW9"/>
    <dbReference type="STRING" id="101091.A0A1C7NCW9"/>
    <dbReference type="InParanoid" id="A0A1C7NCW9"/>
    <dbReference type="OrthoDB" id="5340910at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00174">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.40">
        <property type="entry name" value="SH3 Domains"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050384">
        <property type="entry name" value="Endophilin_SH3RF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036028">
        <property type="entry name" value="SH3-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001452">
        <property type="entry name" value="SH3_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14167:SF81">
        <property type="entry name" value="ENDOPHILIN-A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14167">
        <property type="entry name" value="SH3 DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00018">
        <property type="entry name" value="SH3_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14604">
        <property type="entry name" value="SH3_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00452">
        <property type="entry name" value="SH3DOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00326">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50044">
        <property type="entry name" value="SH3-domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50002">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="9" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0728">SH3 domain</keyword>
    <keyword evidence="9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="SH3" evidence="8">
        <location>
            <begin position="1"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="domain" description="SH3" evidence="8">
        <location>
            <begin position="65"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="domain" description="SH3" evidence="8">
        <location>
            <begin position="211"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="163"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="274"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="465"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="163"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="197"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="315"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="7">
        <location>
            <begin position="328"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="413"/>
            <end position="424"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OBZ86800.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="496" mass="54593" checksum="23B7353F08D8AB11" modified="2016-11-30" version="1">MKAELYKVLYDHETDQEDELAVKANEIIRVTNKDSPDWWLAEKVDNSKEFGLVPSNFVEKIAHEEDKKLAMVLQDYTAQSSDELTLQANGIITILDQDVAEGWWKGDLNGKIGVFPADHVTLLSESTHEQGRSKKDGFKLAAFGVKQGGIGSILAGGLGLKRSSTTGGHRTSIQSTTVSSSAESQPMAIPPRPQPVKTQSTASKSSSSTHTSPTKAMILHDYKPENDDEIQLMRGEYVTILDQMENDGWWKGKNEAGNIGVFPSNFAQIVDQEVLSPPPRPTRTRPATVVKPETTPVAKPDTTQAQPPPVPVGTRPTSLLTQRDVSSTPPPRPTTLPPRPQTQPVAPPRRIDTNKHKRMPSIPLTSPDLPPLSPVHDQKPTRPIPQPGEMVAQKSPTDVLQTMAKPPKILTKSKPSTETNSQEESVPVIPKRSMPSVQTALENDSAMLDAGQVRRLIQAETDALRQMFEAKLEQERQERLKLRAELQQLKASLHLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NDY2</accession>
    <name>A0A1C7NDY2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_04652</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000232">
        <property type="protein sequence ID" value="OBZ87291.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NDY2"/>
    <dbReference type="InParanoid" id="A0A1C7NDY2"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="77"/>
            <end position="96"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ87291.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="96" mass="10923" checksum="BF99FDFD1F53FA9C" modified="2016-11-30" version="1">MWKRERMMVDVVSVAHQSSHPPPLQNRTNYPLGDIQDTIDNFYAGHEFSALGELINPKKRPLSLENTITITTIKKQKVPNQPSNPPTVILIHQQDP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NE56</accession>
    <name>A0A1C7NE56_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_06306</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000375">
        <property type="protein sequence ID" value="OBZ85644.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="InParanoid" id="A0A1C7NE56"/>
    <dbReference type="OrthoDB" id="2261338at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ85644.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="352" mass="40936" checksum="C3E0B83E3FFDDD5E" modified="2016-11-30" version="1">MYNKISKKVKLVCDFYAENEENHVPDDAKWCKENIQTLTAKAFFHEYNFTDSRKDARRYNTILQKYLINNEMVQQLTREFTAFKLSSDYKNYWKEKRRNTIRDRIHEICADYVGDVAEQEANELRNGDEELSTQTQARIGEIIPDAAASEVNLNDEQARTLLYDEPVQEPPHHEHIQQEPLNDIQDCFRIFKNEVKRMIQGNQTFKMEEHVQELLSLNNILLLQPLQYSHLMRSVFTDSLLAKIHDEFQKKIEFPDMKFTPAEFMSIVGNIMNLDSGITSVLSTTAGLLQIASKMPYEKQRVIVGLAMLIQKLPKNSMSDVSAISETELWXXXXXXXXXXXXXXNMLTLKLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NED8</accession>
    <name>A0A1C7NED8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 9">Lactoylglutathione lyase</fullName>
            <ecNumber evidence="3 9">4.4.1.5</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Glyoxalase I</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="primary">GLO1</name>
        <name evidence="11" type="ORF">A0J61_04477</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>(R)-S-lactoylglutathione = methylglyoxal + glutathione</text>
            <dbReference type="Rhea" id="RHEA:19069"/>
            <dbReference type="ChEBI" id="CHEBI:17158"/>
            <dbReference type="ChEBI" id="CHEBI:57474"/>
            <dbReference type="ChEBI" id="CHEBI:57925"/>
            <dbReference type="EC" id="4.4.1.5"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="8">Binds 1 zinc ion per subunit. In the homodimer, two zinc ions are bound between subunits.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1 9">Secondary metabolite metabolism; methylglyoxal degradation; (R)-lactate from methylglyoxal: step 1/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the glyoxalase I family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.4.1.5" evidence="3 9"/>
    <dbReference type="EMBL" id="LUGH01000220">
        <property type="protein sequence ID" value="OBZ87473.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NED8"/>
    <dbReference type="STRING" id="101091.A0A1C7NED8"/>
    <dbReference type="InParanoid" id="A0A1C7NED8"/>
    <dbReference type="OrthoDB" id="16820at2759"/>
    <dbReference type="UniPathway" id="UPA00619">
        <property type="reaction ID" value="UER00675"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004462">
        <property type="term" value="F:lactoylglutathione lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd07233">
        <property type="entry name" value="GlxI_Zn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.180.10">
        <property type="entry name" value="2,3-Dihydroxybiphenyl 1,2-Dioxygenase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029068">
        <property type="entry name" value="Glyas_Bleomycin-R_OHBP_Dase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004360">
        <property type="entry name" value="Glyas_Fos-R_dOase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004361">
        <property type="entry name" value="Glyoxalase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018146">
        <property type="entry name" value="Glyoxalase_1_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037523">
        <property type="entry name" value="VOC_core"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00068">
        <property type="entry name" value="glyox_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10374:SF30">
        <property type="entry name" value="LACTOYLGLUTATHIONE LYASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10374">
        <property type="entry name" value="LACTOYLGLUTATHIONE LYASE GLYOXALASE I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00903">
        <property type="entry name" value="Glyoxalase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54593">
        <property type="entry name" value="Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00934">
        <property type="entry name" value="GLYOXALASE_I_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00935">
        <property type="entry name" value="GLYOXALASE_I_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51819">
        <property type="entry name" value="VOC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9 11" id="KW-0456">Lyase</keyword>
    <keyword evidence="4 8 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8 9" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="VOC" evidence="10">
        <location>
            <begin position="9"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor/acceptor" evidence="7">
        <location>
            <position position="164"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="90"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="118"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="164"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012081"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR604361-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR604361-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU361179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="OBZ87473.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="178" mass="20276" checksum="DDCECD72E43AD2D4" modified="2016-11-30" version="1">MSTDTSKYIFNHTMIRVKDPKASIHFYTEVLGMKIEQNRPLTHIQLFRLITKSDFPNAKFTLYFLAFVDKVPESEEEKKKLAFSIPGVLELTHNWGTEDQEDFAYANGNSDPGRGFGHIAVLVDNIEKACERFESLGVKFIKKLTDGTMKNIAFIADPDNYWVEIIANPALTDVCTSY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NEV9</accession>
    <name>A0A1C7NEV9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Vacuolar protein-sorting-associated protein 36</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">ESCRT-II complex subunit VPS36</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="primary">Vps36</name>
        <name evidence="13" type="ORF">A0J61_04457</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Component of the ESCRT-II complex (endosomal sorting complex required for transport II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs.</text>
    </comment>
    <comment type="subunit">
        <text evidence="10">Component of the endosomal sorting complex required for transport II (ESCRT-II).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="10">Endosome</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 10">Belongs to the VPS36 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000218">
        <property type="protein sequence ID" value="OBZ87500.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NEV9"/>
    <dbReference type="FunCoup" id="A0A1C7NEV9">
        <property type="interactions" value="156"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NEV9"/>
    <dbReference type="InParanoid" id="A0A1C7NEV9"/>
    <dbReference type="OrthoDB" id="271448at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000814">
        <property type="term" value="C:ESCRT II complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031902">
        <property type="term" value="C:late endosome membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032266">
        <property type="term" value="F:phosphatidylinositol-3-phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043130">
        <property type="term" value="F:ubiquitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043328">
        <property type="term" value="P:protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.10:FF:000165">
        <property type="entry name" value="Vacuolar protein sorting protein (Vps36)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.260">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.1060.10">
        <property type="entry name" value="Zinc finger, RanBP2-type"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021648">
        <property type="entry name" value="GLUE_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040608">
        <property type="entry name" value="Snf8/Vps36"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037855">
        <property type="entry name" value="Vps36"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001876">
        <property type="entry name" value="Znf_RanBP2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036443">
        <property type="entry name" value="Znf_RanBP2_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13128">
        <property type="entry name" value="VACUOLAR PROTEIN-SORTING-ASSOCIATED PROTEIN 36"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13128:SF12">
        <property type="entry name" value="VACUOLAR PROTEIN-SORTING-ASSOCIATED PROTEIN 36"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04157">
        <property type="entry name" value="EAP30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11605">
        <property type="entry name" value="Vps36_ESCRT-II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00641">
        <property type="entry name" value="Zn_ribbon_RanBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00547">
        <property type="entry name" value="ZnF_RBZ"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90209">
        <property type="entry name" value="Ran binding protein zinc finger-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51495">
        <property type="entry name" value="GLUE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01358">
        <property type="entry name" value="ZF_RANBP2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50199">
        <property type="entry name" value="ZF_RANBP2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="10" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 10" id="KW-0967">Endosome</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 10" id="KW-0653">Protein transport</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 10" id="KW-0813">Transport</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <keyword evidence="5 9" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="GLUE N-terminal" evidence="12">
        <location>
            <begin position="7"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="domain" description="RanBP2-type" evidence="11">
        <location>
            <begin position="111"/>
            <end position="140"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022753"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00322"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU367095"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51495"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="OBZ87500.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="470" mass="52661" checksum="9C23E5FB79775DDE" modified="2016-11-30" version="1">MEFFKETILSSSRRPELLADESILIQQGQVGLYSGKQKIEYYQDGICYLTTHRIIYVDSQVPLERSVELNLCKIQHVDSYNGFLRSSPKIILDILQDNRESVDQVNHTSSKQGVWACPICFFSNKASSDQCELCGVRNKQEENTILPDTNATTDTSTCSVCTFQNHPSMVQCEMCGAELPKIGTAATTSKQLTVESGQIRLSFRQGGHTSFLSKLKTALNTKQWEKKAKQTSVTPVRGVGINAIEDRIQKTTLEANETMTDAFQDLDRLMAKATEMVKLAESISNKVSKDTANNEDSEMSTLRTHLLNLGIVSPVTKGSAGSIYHQELSKELADFLSKFFERQDDMKSLTDVYCIFNRMRGVALISPEDLYKASQQFESLKLPFRLRKFSSGLLVIQSIDMDDSRAASRVLKHVKHQGLLTALKLAELENLALPVATEQLMMTERMGFICRDEGPAGLSFYENLFLNHAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NF10</accession>
    <name>A0A1C7NF10_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_04808</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000243">
        <property type="protein sequence ID" value="OBZ87146.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NF10"/>
    <dbReference type="STRING" id="101091.A0A1C7NF10"/>
    <dbReference type="InParanoid" id="A0A1C7NF10"/>
    <dbReference type="OrthoDB" id="2281978at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="265"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="25"/>
            <end position="36"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ87146.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="289" mass="32889" checksum="FA5AD0AFFD9AAF08" modified="2016-11-30" version="1">MKPRYRTKDDRYKRVNRNFAGLPSDSEDDDHIEDDGSVSTTSSSLQNEVYFEQPKNAFPKQTKVKTTVPSDDSDSSSQDVPLKTAYPKRSSRQDGLYRNNRSAPSLPHHLKQHEVHHQAHTKHGHRSTSTEDIKRLMHHAPTKQMRMSGMDLLIQREQEKAEAKRQKPKINPGKAKIEGLLARLPEPGAHNINFQQTLMTNSPTPSHSMHRNKREASFCSLSSNLFPPIPTHTGGPMLDYRNRAHYSMPMSHPSGYFMLQQTMGRSGSNMPLSPKQPIVINKKQQRTPI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NF56</accession>
    <name>A0A1C7NF56_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein C3G9.05</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">A0J61_04205</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000200">
        <property type="protein sequence ID" value="OBZ87741.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NF56"/>
    <dbReference type="STRING" id="101091.A0A1C7NF56"/>
    <dbReference type="InParanoid" id="A0A1C7NF56"/>
    <dbReference type="OrthoDB" id="5588096at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005078">
        <property type="term" value="F:MAP-kinase scaffold activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.330">
        <property type="entry name" value="Nucleotidyltransferases domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022018">
        <property type="entry name" value="GIT1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013724">
        <property type="entry name" value="GIT_SHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039892">
        <property type="entry name" value="Spa2/Sph1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056439">
        <property type="entry name" value="VBS_C3G9"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21601:SF0">
        <property type="entry name" value="PROTEIN SPA2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21601">
        <property type="entry name" value="SPA2 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12205">
        <property type="entry name" value="GIT1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08518">
        <property type="entry name" value="GIT_SHD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23742">
        <property type="entry name" value="VBS_C3G9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00555">
        <property type="entry name" value="GIT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57997">
        <property type="entry name" value="Tropomyosin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="GIT Spa2 homology (SHD)" evidence="3">
        <location>
            <begin position="79"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="domain" description="GIT Spa2 homology (SHD)" evidence="3">
        <location>
            <begin position="126"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="283"/>
            <end position="359"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OBZ87741.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="658" mass="75118" checksum="5AF8FBF349C4BC46" modified="2016-11-30" version="1">MSYQQSSPLRSVSSEEWAKFKTQSTSSAAYSVSSSSSRQTTVSIQESYAKQYYVELKRYLHDMLTAELAEGVPPQRTTARQKLSRLNNLQFHELATDVYDEMMRRQSDNKSYLPRKDEYHSRRNQAREKLSTLPLYRFQDLASDVYHELRRRYPQIMNMEEEEVPPMPTKSLEPQAHPSQSTNIVPVKGMISVENVSFGDENDEGRPTTEPENLQSLDSLMADLGNMVQTPNDHPESRSSNIETMRHNYELKISSMAKRIKMLELSLDNEQNHGSDSSPSMRLRQMQQEYDQLDKRYNQLSQDHQEQQMAVREVKNEMKQLIEEIKSLSSKNEALRVEKEKADAQIKAMADEMKAWKRKYETVSMELRGFKVKSISLENANVPNELLLKPSSKGAIAHQYIIDFQTAIDELMKTSRSSKPTDVLMSMRVIVMACKAITTEVENHETQVELPPETRDQLYDIKKRFSDELTSLLAASKSYASGMGITPVSLIDASASNLTNTIVDLVRLLGMKPIESFQAEPSHQPSSQHNNVMKPRELSQFLKTETDHIVSSVQNLLSALRSSDDSLYNIITSIIDIVSNIVHTSRMTFSSGEGIRYQNQGHAILSDLDNCNNKIVRIRDTSFAHSPQNANAIAKRNLAQESYEIAKYTKELIRMLDM</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NF90</accession>
    <name>A0A1C7NF90_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">40S ribosomal protein S20</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">rps20_0</name>
        <name evidence="6" type="ORF">A0J61_04172</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uS10 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000198">
        <property type="protein sequence ID" value="OBZ87771.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NF90"/>
    <dbReference type="FunCoup" id="A0A1C7NF90">
        <property type="interactions" value="390"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NF90"/>
    <dbReference type="InParanoid" id="A0A1C7NF90"/>
    <dbReference type="OrthoDB" id="10248551at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015935">
        <property type="term" value="C:small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.600:FF:000002">
        <property type="entry name" value="40S ribosomal protein S20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.600">
        <property type="entry name" value="Ribosomal protein S10 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00508">
        <property type="entry name" value="Ribosomal_uS10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001848">
        <property type="entry name" value="Ribosomal_uS10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027486">
        <property type="entry name" value="Ribosomal_uS10_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036838">
        <property type="entry name" value="Ribosomal_uS10_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005729">
        <property type="entry name" value="Ribosomal_uS10_euk/arc"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01046">
        <property type="entry name" value="uS10_euk_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11700">
        <property type="entry name" value="30S RIBOSOMAL PROTEIN S10 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00338">
        <property type="entry name" value="Ribosomal_S10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00971">
        <property type="entry name" value="RIBOSOMALS10"/>
    </dbReference>
    <dbReference type="SMART" id="SM01403">
        <property type="entry name" value="Ribosomal_S10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54999">
        <property type="entry name" value="Ribosomal protein S10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 6" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Small ribosomal subunit protein uS10" evidence="5">
        <location>
            <begin position="26"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM01403"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OBZ87771.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="122" mass="13829" checksum="07C623E1122D60E8" modified="2016-11-30" version="1">MSYVAKNTTQKPGLEEQEQPKIHRIRITLTSRNVKNLEKVSADLIQRAKDKQLKVKGPVRLPTKVLRITTRKSPCGNGSETFDKYEMKIHKRLIDLHSPSEIVKQITSISIEPGVEVEVTIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NF98</accession>
    <name>A0A1C7NF98_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_05926</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000335">
        <property type="protein sequence ID" value="OBZ86024.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NF98"/>
    <dbReference type="InParanoid" id="A0A1C7NF98"/>
    <dbReference type="OrthoDB" id="10249888at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="16"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="46"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="95"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="122"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="202"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="235"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="244"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ86024.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="244" mass="29188" checksum="6F1724CBDC61FA6D" modified="2016-11-30" version="1" fragment="single">SDKDGEKFFDSKEYQEKEEEEEEEFFDCENEDEAEQPGQPEPAEEKEDKREIKDQQEDQERKDGNATMHKQKRKLEECESFSQVDRPIHPKKRKIREEGDKGPSHHVEKLAECLRQKRKERDEEEDEDKDEEEDEGEEEDEDKDKEEDEDKDKEEDEDKDKDEDEGEDKDEDEGEDKDEDEGEDKDEDEGEDKDEAEVDNGLSHHIERSSECLRQKRKERDTSEDEDEEEATSRPQKRRLLNNM</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NFI9</accession>
    <name>A0A1C7NFI9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Thymidylate kinase</fullName>
            <ecNumber evidence="3">2.7.4.9</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">DTYMK</name>
        <name evidence="11" type="ORF">A0J61_04644</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Pyrimidine metabolism; dTTP biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the thymidylate kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.4.9" evidence="3"/>
    <dbReference type="EMBL" id="LUGH01000231">
        <property type="protein sequence ID" value="OBZ87316.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NFI9"/>
    <dbReference type="FunCoup" id="A0A1C7NFI9">
        <property type="interactions" value="443"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NFI9"/>
    <dbReference type="InParanoid" id="A0A1C7NFI9"/>
    <dbReference type="OrthoDB" id="425602at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004798">
        <property type="term" value="F:dTMP kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004550">
        <property type="term" value="F:nucleoside diphosphate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006233">
        <property type="term" value="P:dTDP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006235">
        <property type="term" value="P:dTTP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006227">
        <property type="term" value="P:dUDP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01672">
        <property type="entry name" value="TMPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000679">
        <property type="entry name" value="Thymidylate kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00165">
        <property type="entry name" value="Thymidylate_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039430">
        <property type="entry name" value="Thymidylate_kin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018095">
        <property type="entry name" value="Thymidylate_kin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018094">
        <property type="entry name" value="Thymidylate_kinase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00041">
        <property type="entry name" value="DTMP_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10344">
        <property type="entry name" value="THYMIDYLATE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10344:SF1">
        <property type="entry name" value="THYMIDYLATE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02223">
        <property type="entry name" value="Thymidylate_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01331">
        <property type="entry name" value="THYMIDYLATE_KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8 11" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-0545">Nucleotide biosynthesis</keyword>
    <keyword evidence="7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Thymidylate kinase-like" evidence="10">
        <location>
            <begin position="16"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="11">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00017144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF02223"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="OBZ87316.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="214" mass="24814" checksum="E4BADA1275DF9083" modified="2016-11-30" version="1" fragment="single">NPFLFNMVQRGLFIVVEGCDRSGKTTQCDILVNKLNQHGIATELVKFPDRTTQTGKMIDSYLQQKSDLDDHAIHLLFSSNRWEAMKDLKAKLDQGTTLVVDRYAFSGVAFSSAKGLDLDWCKQPDVGLLSPDLVLFLDLTIDEAEKRGGFGEERYEKRELQIKVREEFFRLKDDSWKFIEASQSKEKVEEDIWETIQQCRANSRLDELHYNLWK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NFQ8</accession>
    <name>A0A1C7NFQ8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Vacuolar protein 8</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">VAC8_0</name>
        <name evidence="9" type="ORF">A0J61_04088</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Vacuole membrane</location>
            <topology evidence="1">Lipid-anchor</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the beta-catenin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000192">
        <property type="protein sequence ID" value="OBZ87868.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NFQ8"/>
    <dbReference type="FunCoup" id="A0A1C7NFQ8">
        <property type="interactions" value="60"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NFQ8"/>
    <dbReference type="InParanoid" id="A0A1C7NFQ8"/>
    <dbReference type="OrthoDB" id="7537227at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000329">
        <property type="term" value="C:fungal-type vacuole membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043495">
        <property type="term" value="F:protein-membrane adaptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000045">
        <property type="term" value="P:autophagosome assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071562">
        <property type="term" value="P:nucleus-vacuole junction assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.10.10:FF:000131">
        <property type="entry name" value="Vacuolar protein 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.10.10:FF:000128">
        <property type="entry name" value="Vacuolar protein-like protein 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000225">
        <property type="entry name" value="Armadillo"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045156">
        <property type="entry name" value="Vac8"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47249">
        <property type="entry name" value="VACUOLAR PROTEIN 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47249:SF1">
        <property type="entry name" value="VACUOLAR PROTEIN 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00514">
        <property type="entry name" value="Arm"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="SMART" id="SM00185">
        <property type="entry name" value="ARM"/>
        <property type="match status" value="9"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50176">
        <property type="entry name" value="ARM_REPEAT"/>
        <property type="match status" value="7"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0926">Vacuole</keyword>
    <feature type="repeat" description="ARM" evidence="8">
        <location>
            <begin position="90"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="repeat" description="ARM" evidence="8">
        <location>
            <begin position="131"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="repeat" description="ARM" evidence="8">
        <location>
            <begin position="172"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="repeat" description="ARM" evidence="8">
        <location>
            <begin position="213"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="repeat" description="ARM" evidence="8">
        <location>
            <begin position="256"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="repeat" description="ARM" evidence="8">
        <location>
            <begin position="297"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="repeat" description="ARM" evidence="8">
        <location>
            <begin position="338"/>
            <end position="381"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004592"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022554"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00026209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00259"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OBZ87868.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="561" mass="61395" checksum="9DBE988B703A5890" modified="2016-11-30" version="1">MGNSCSCCSSCCGKRSRTGLYEPLLQENEREAIAELLQYLENRSDTNFFEGDPLQALSTLAYSDNIDLQRSAALAFAEITEKDVRQVGRDTLDPILFLLQSHDVEVQRAASAALGNLAVNTENKLLIVKLGGLDQLIRQMGSPNVEVQCNAVGCITNLATHDENKTKIAKSDALRLLVDLAKSKDQRVQRNATGALLNMTHTQENRQQLVNAGAIPVLIGLLSSPDADVQYYCTTALSNIAVDAGNRKKLAQTDSRLVNYLIALMDTKSLKVQCQAALALRNLASDEKYQLEIVRCKGLPPLLRLLKSSFLPLILSSVACIRNISIHPSNESPIIDGGFVNPLIELLAYDENEEIQCHAISTLRNLAASSERNKRAIVEAGAVERIKSLIDKVPPSVQTEMTAAIAVLALSDDLKQRLLSMGILDVLVELTSSRNMEVEGNSAAAIGNLSSKVQDYTPFVTAWEAPSGGLKKFLIQFLSEQQDIAFQHIGVWTIEQFLDGGDTRLMSLIANSTQITQSVERIVREGQSPKAEHHEDSDEGDIYGLAKRVMNTLNEIKSSNH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NG64</accession>
    <name>A0A1C7NG64_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">F-box/TPR repeat protein pof3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">pof3</name>
        <name evidence="2" type="ORF">A0J61_05593</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000306">
        <property type="protein sequence ID" value="OBZ86354.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NG64"/>
    <dbReference type="STRING" id="101091.A0A1C7NG64"/>
    <dbReference type="InParanoid" id="A0A1C7NG64"/>
    <dbReference type="OrthoDB" id="2218971at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019005">
        <property type="term" value="C:SCF ubiquitin ligase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031146">
        <property type="term" value="P:SCF-dependent proteasomal ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006553">
        <property type="entry name" value="Leu-rich_rpt_Cys-con_subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13318">
        <property type="entry name" value="PARTNER OF PAIRED, ISOFORM B-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12937">
        <property type="entry name" value="F-box-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00367">
        <property type="entry name" value="LRR_CC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="1">
        <location>
            <begin position="140"/>
            <end position="187"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ86354.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="569" mass="65358" checksum="450E4E847759AD31" modified="2016-11-30" version="1">MYKRKQDPQQSQEPWKAVFSDAYQAFKENNFKDSAVLFTRALSLKPGHVTILDCRAACYEKLNELEPALRDAYSIISAAPTEARGYLRVGKLLMLQKKFKHAVNVYKRALTKVDLSDSRYAQIQSMKNAAEKIVTPPASLDFMQVLPYDVVSLIFSYLSFDRRIQCTGVCQGWRQFALNWSGMWRDLDFGNRKVSITTIKKYLSYAKNRHVRRFALMDANQTMMKRCLQALIDHDCQYIECLDFVRCEIPMTLWTRMLRLVGKHVRNIRLDESTLEISRLFEEMIPNMPQLTQISMIGLEIDTMDAWLQSRGGTSTVLNLTHLRLSLNSAEAAAWVIKHCPRLQMLDFYTPNVALSDLTLRLTNTDMMHLKEFYYTVGSGFQRNTQWQSHFSDMNQNQGLTTLSIHGDLSLTGELLEQMVRKYHTTLTHLTISDCRSLDNRLAQLVIAPGLPQVQTLNINMYISLEEWDLHTIISSCPTIENLSMTWIQGVTDSVLRDVQTTTKKLKKLDISNCNNVTGVGLQYIVKAHQSTIEKLVLNNCHRIGPDAISWAASVLEKHVIECKYNIMR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NG83</accession>
    <name>A0A1C7NG83_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="8">mRNA export factor mex67</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">mex67_1</name>
        <name evidence="8" type="ORF">A0J61_03792</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the NXF family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000171">
        <property type="protein sequence ID" value="OBZ88161.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NG83"/>
    <dbReference type="STRING" id="101091.A0A1C7NG83"/>
    <dbReference type="InParanoid" id="A0A1C7NG83"/>
    <dbReference type="OrthoDB" id="25872at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016973">
        <property type="term" value="P:poly(A)+ mRNA export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.450.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040736">
        <property type="entry name" value="Mex67_RRM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032710">
        <property type="entry name" value="NTF2-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002075">
        <property type="entry name" value="NTF2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018222">
        <property type="entry name" value="Nuclear_transport_factor_2_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057125">
        <property type="entry name" value="NXF1/2/3/5-like_LRR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030217">
        <property type="entry name" value="NXF_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10662">
        <property type="entry name" value="NUCLEAR RNA EXPORT FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10662:SF22">
        <property type="entry name" value="NUCLEAR RNA EXPORT FACTOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24048">
        <property type="entry name" value="LRR_NXF1-5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22602">
        <property type="entry name" value="NXF_NTF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18444">
        <property type="entry name" value="RRM_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54427">
        <property type="entry name" value="NTF2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50177">
        <property type="entry name" value="NTF2_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0509">mRNA transport</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="NTF2" evidence="7">
        <location>
            <begin position="367"/>
            <end position="516"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="172"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="26"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="176"/>
            <end position="194"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022816"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OBZ88161.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="522" mass="58782" checksum="79153A065DDBDCCD" modified="2016-11-30" version="1">MYSDNTSNRGSRGGGGRGRGRGRGGYNNNTNHHYNNNNNTNNNHTNNVPITSRLGPVGGKAFSSNSYNQGRNTRHRGNTEQFNNAFTSEDTDMNIEQEGGHVVVVSGYPPGAEEKILGFLKRKARGDWEALHIQNEHNGMQITVANQAMVDTLCRMNNYEFGKATLRIEGKESGYRPNSNRGNTNSNTRTSRPPAARSAFLAEFLEKRWNPQAGFLDMDDLPDTSHNISVVISKLLTEAKYLFGDSLITISFARNKLWSVSPLTKLADQFPNIQNLSIAENEIADFRKLDLLANRFPRLQELVLSGNPIQKNFSSDRYQKEVLSRFPTITFLDMQPVNEAPMAQTGTQELPVSVQPYFFDQDSSRSFAQDFLSTYFPLFDSNRVSLVDMYDAQAVFSSVFSKGNEHQNHAWGSSKMTPGQRMVVGNQNIIQRIQQLPQTVHDLSRPDKFVIDAWQTSYSETYPVVLFLTVHAEFAELPLGTPLQFDRNFILIPSNPGSRAHAAGWQYMILSDSLLIRTNKRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NGC4</accession>
    <name>A0A1C7NGC4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_04344</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000211">
        <property type="protein sequence ID" value="OBZ87606.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NGC4"/>
    <dbReference type="STRING" id="101091.A0A1C7NGC4"/>
    <dbReference type="InParanoid" id="A0A1C7NGC4"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="16"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="178"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="214"/>
            <end position="233"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ87606.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="286" mass="31974" checksum="8BE2769874F295DF" modified="2016-11-30" version="1">MLLEEKSFSKILTTSAYLLLLVLSPIELASLLNSLLYANDFAPYSFMLYDAKPSDTLSRPQLSYRFTFCNPSNIPFSAGGYIDLLELVENNTTKALRVMNQLTTIGLIPPPSGFYPPLSSRFYAHIIRQQLEYGLSLSLSVCLSNDRLSFQLARTGPRQLSTLFYGGYASPYKTSHNIIYCLIFASFPAHLIGTVSHVADNRDGVNHSLTLPPINLYAVLLLKATQILISLAAHRYTSNLYSIYQWHMESAVVIFFSAIPEYHLDDLRSVTSTHPAHSLCFMPSIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NGD1</accession>
    <name>A0A1C7NGD1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_03757</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000168">
        <property type="protein sequence ID" value="OBZ88201.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NGD1"/>
    <dbReference type="InParanoid" id="A0A1C7NGD1"/>
    <dbReference type="OrthoDB" id="2290958at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="65"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="67"/>
            <end position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ88201.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="285" mass="32929" checksum="B6A6F2D400722EE8" modified="2016-11-30" version="1">MTSKKDYTQKLEFAFNYIIGKFIYHTKKKPLKKTFSNDALFEHTQYQLNKTKKCHNANVRHKHHSHSFSMPFSSNATASPLPPSSPLSNNQLTPYCCRYSPNAHQTRKRPHHRHYSSCISAFDMTVHSEDLTSKEFADIVGIQILSETMDERQKITTPSLIANSSKISSSILLKESDSSSMFYPISDILSLDDEDDHEEEEEEEIDETIHIWDNGFWQHPNKPANETLSSLHDMIRYDGTMCIKRGRFEILLTENCTSSATIPPKRPDRMVFEWKRRKATLHSAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NGH2</accession>
    <name>A0A1C7NGH2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Calmodulin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">calm1</name>
        <name evidence="6" type="ORF">A0J61_03756</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the calmodulin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000168">
        <property type="protein sequence ID" value="OBZ88202.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NGH2"/>
    <dbReference type="FunCoup" id="A0A1C7NGH2">
        <property type="interactions" value="182"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NGH2"/>
    <dbReference type="InParanoid" id="A0A1C7NGH2"/>
    <dbReference type="OrthoDB" id="26525at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016460">
        <property type="term" value="C:myosin II complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00051">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.238.10:FF:000006">
        <property type="entry name" value="Calmodulin 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.238.10:FF:000398">
        <property type="entry name" value="Calmodulin-like protein 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050230">
        <property type="entry name" value="CALM/Myosin/TropC-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23048:SF0">
        <property type="entry name" value="CALMODULIN LIKE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23048">
        <property type="entry name" value="MYOSIN LIGHT CHAIN 1, 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13499">
        <property type="entry name" value="EF-hand_7"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00450">
        <property type="entry name" value="RECOVERIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00054">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0106">Calcium</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="EF-hand" evidence="5">
        <location>
            <begin position="8"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="5">
        <location>
            <begin position="44"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="5">
        <location>
            <begin position="81"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="5">
        <location>
            <begin position="117"/>
            <end position="151"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OBZ88202.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="151" mass="17199" checksum="11BAB00E75F71E00" modified="2016-11-30" version="1">MADQLTEEQIAEFREAFQLFDKDGDGSITTKELGTVMRSLNLNPTEAELQDMINEIDTDGNGRIDFSEFLTMLARKMKDTDSQEEIQEAFKVFDKDGNGYISAAELRHVMTSLGEKLTEEEVDEMIREADVDGDGQINYEEFVKMMVCVYV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NGL5</accession>
    <name>A0A1C7NGL5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">NADH-ubiquinone oxidoreductase 19 subunit, mitochondrial</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">G17A4.170</name>
        <name evidence="5" type="ORF">A0J61_05424</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the complex I 20 kDa subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000292">
        <property type="protein sequence ID" value="OBZ86524.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NGL5"/>
    <dbReference type="STRING" id="101091.A0A1C7NGL5"/>
    <dbReference type="InParanoid" id="A0A1C7NGL5"/>
    <dbReference type="OrthoDB" id="268400at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045271">
        <property type="term" value="C:respiratory chain complex I"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008137">
        <property type="term" value="F:NADH dehydrogenase (ubiquinone) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048038">
        <property type="term" value="F:quinone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009060">
        <property type="term" value="P:aerobic respiration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015990">
        <property type="term" value="P:electron transport coupled proton transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032981">
        <property type="term" value="P:mitochondrial respiratory chain complex I assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.12280:FF:000001">
        <property type="entry name" value="NADH-quinone oxidoreductase subunit B 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12280">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01356">
        <property type="entry name" value="NDH1_NuoB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006137">
        <property type="entry name" value="NADH_UbQ_OxRdtase-like_20kDa"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006138">
        <property type="entry name" value="NADH_UQ_OxRdtase_20Kd_su"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01957">
        <property type="entry name" value="nuoB_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF005012">
        <property type="entry name" value="PRK06411.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11995">
        <property type="entry name" value="NADH DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11995:SF14">
        <property type="entry name" value="NADH DEHYDROGENASE [UBIQUINONE] IRON-SULFUR PROTEIN 7, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01058">
        <property type="entry name" value="Oxidored_q6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56770">
        <property type="entry name" value="HydA/Nqo6-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01150">
        <property type="entry name" value="COMPLEX1_20K"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="3" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2 3" id="KW-0520">NAD</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0830">Ubiquinone</keyword>
    <feature type="domain" description="NADH:ubiquinone oxidoreductase-like 20kDa subunit" evidence="4">
        <location>
            <begin position="81"/>
            <end position="189"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU004464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01058"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OBZ86524.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="212" mass="23903" checksum="7218585997B2001E" modified="2016-11-30" version="1">MATSALGLQFAKRAMTLSAPKTFAATSQRFMSTEVVRNIDQIKDITVTPNNKAEYVLSTVDRVVNWAREGSIWPMTFGLACCAVEMMHCSTPRYDQDRIGIVFRATPRQSDIMIVAGTLTNKMAPALRKVYDQMPEPRWVISMGSCANGGGYYHYSYSVVRGCDRIVPVDIYVPGCPPTAEALLYGIFQLQKKMRRTKITQLWYRKLNVDQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NH84</accession>
    <name>A0A1C7NH84_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Negative regulator of sexual conjugation and meiosis</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">ran1_4</name>
        <name evidence="6" type="ORF">A0J61_03609</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the protein kinase superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000158">
        <property type="protein sequence ID" value="OBZ88350.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NH84"/>
    <dbReference type="STRING" id="101091.A0A1C7NH84"/>
    <dbReference type="InParanoid" id="A0A1C7NH84"/>
    <dbReference type="OrthoDB" id="541276at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035556">
        <property type="term" value="P:intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000571">
        <property type="entry name" value="Maternal embryonic leucine zipper kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24346">
        <property type="entry name" value="MAP/MICROTUBULE AFFINITY-REGULATING KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24346:SF30">
        <property type="entry name" value="MATERNAL EMBRYONIC LEUCINE ZIPPER KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3 4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="1 3 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="5">
        <location>
            <begin position="22"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="51"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OBZ88350.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="365" mass="42101" checksum="29E7DDAC060659FB" modified="2016-11-30" version="1">MALSLNWDQLSDSMVDKRIQSYQLLEELGRGTYGCLFLGQSLVDNHYVAIKVLSKRGLDPTQLQLQQLELDIQHQLNHPYLLGLEDVVHEEDFIYMIMELCDGGDLFEYVIQNPEREDATIKAFFVQILEAIEYLHGHGIYHRDIKLENILLSSQDTCKVADFGLATRDRFSFEFGCGSTTYLGPEHFATDEDEQDGFDAYDAAASDIWSLGILLLALLFGKNPWNEATEEDMGFAEFKRNPAYLAHSLFPRLSHECTRFLLDHVLCVNPLDRCDIQTMKETFMNLSQLTVMPVDIIPVSHHSTKASYDSAYFSQETVGLSWSDMVEQDLEEEEDDYDEDDDDFEHLTEDEELFIHSQEKESWWL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NHF0</accession>
    <name>A0A1C7NHF0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Protein BOI2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">BOI2</name>
        <name evidence="3" type="ORF">A0J61_03527</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000153">
        <property type="protein sequence ID" value="OBZ88420.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NHF0"/>
    <dbReference type="FunCoup" id="A0A1C7NHF0">
        <property type="interactions" value="72"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NHF0"/>
    <dbReference type="InParanoid" id="A0A1C7NHF0"/>
    <dbReference type="OrthoDB" id="73680at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd09535">
        <property type="entry name" value="SAM_BOI-like_fungal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.29.30:FF:000286">
        <property type="entry name" value="PH-protein kinase domain containing protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.418.10">
        <property type="entry name" value="Calponin-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.50">
        <property type="entry name" value="Transcription Factor, Ets-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001715">
        <property type="entry name" value="CH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036872">
        <property type="entry name" value="CH_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001849">
        <property type="entry name" value="PH_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001660">
        <property type="entry name" value="SAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013761">
        <property type="entry name" value="SAM/pointed_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12752:SF9">
        <property type="entry name" value="KRAMER, ISOFORM I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12752">
        <property type="entry name" value="PHOSPHOINOSITOL 3-PHOSPHATE-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00307">
        <property type="entry name" value="CH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00169">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07647">
        <property type="entry name" value="SAM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00233">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00454">
        <property type="entry name" value="SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47576">
        <property type="entry name" value="Calponin-homology domain, CH-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47769">
        <property type="entry name" value="SAM/Pointed domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50003">
        <property type="entry name" value="PH_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50105">
        <property type="entry name" value="SAM_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SAM" evidence="2">
        <location>
            <begin position="44"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="domain" description="PH" evidence="1">
        <location>
            <begin position="144"/>
            <end position="240"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50105"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ88420.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="375" mass="44003" checksum="68716FEA36E12C51" modified="2016-11-30" version="1">MRNQIGLFPKSYIRQVDNPSGILKKAVVRSLLLPQLRSTSPEEWDIDQVQIWLHEMQFDINMIDHFRVQEITGDVLLELTMDFLKELSISTFGKRFRLYTAIHLLREEYHKRMSSKSIENMSSVDQTMKTSVLSHPKQETEDIGPDTKGWLYKQGCKYKQWNKRWFVLKGIHLFYFKSPKDLRMKGIINLRGYRIIPDESIQPGKYSFKAQHFEERTFYFYTDTETSMRQWITPLMKATITRDFHAPVLSSHTIPTVSLSVARRMKPRPPSILLYRKRAHLSKEEDCLEWLNSTVDSGIIRDLQELRTGTVLMDLLEKLSGKKVRHSSLSDLASVFQFLVSEHVLLASQCQIEDIQEGDRDQILILLTHIRQWAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NHY9</accession>
    <name>A0A1C7NHY9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_03300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000139">
        <property type="protein sequence ID" value="OBZ88655.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NHY9"/>
    <dbReference type="STRING" id="101091.A0A1C7NHY9"/>
    <dbReference type="InParanoid" id="A0A1C7NHY9"/>
    <dbReference type="OrthoDB" id="2326382at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038882">
        <property type="entry name" value="Rcf3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39153">
        <property type="entry name" value="AGR244WP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39153:SF1">
        <property type="entry name" value="AGR244WP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="42"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ88655.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="110" mass="12622" checksum="43D74F20CA023E7B" modified="2016-11-30" version="1">MRVVSELDRENASRYAMKGFAIGAAQWAGVGLFASGLLYAFMPWYRRTQTVNKFYIVMCFGLGGGAYKSDRYMVNFERRGRAQTLDEETKRRYELLYGKDFEKTADQAAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NHZ0</accession>
    <name>A0A1C7NHZ0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Peptidyl-prolyl cis-trans isomerase</fullName>
            <shortName evidence="6">PPIase</shortName>
            <ecNumber evidence="6">5.2.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">cyp3</name>
        <name evidence="8" type="ORF">A0J61_03193</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 6">PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 6">
            <text>[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)</text>
            <dbReference type="Rhea" id="RHEA:16237"/>
            <dbReference type="Rhea" id="RHEA-COMP:10747"/>
            <dbReference type="Rhea" id="RHEA-COMP:10748"/>
            <dbReference type="ChEBI" id="CHEBI:83833"/>
            <dbReference type="ChEBI" id="CHEBI:83834"/>
            <dbReference type="EC" id="5.2.1.8"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the cyclophilin-type PPIase family. PPIL1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.2.1.8" evidence="6"/>
    <dbReference type="EMBL" id="LUGH01000133">
        <property type="protein sequence ID" value="OBZ88753.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NHZ0"/>
    <dbReference type="FunCoup" id="A0A1C7NHZ0">
        <property type="interactions" value="643"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NHZ0"/>
    <dbReference type="InParanoid" id="A0A1C7NHZ0"/>
    <dbReference type="OrthoDB" id="271386at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071013">
        <property type="term" value="C:catalytic step 2 spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.100.10:FF:000008">
        <property type="entry name" value="Peptidyl-prolyl cis-trans isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.100.10">
        <property type="entry name" value="Cyclophilin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029000">
        <property type="entry name" value="Cyclophilin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024936">
        <property type="entry name" value="Cyclophilin-type_PPIase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020892">
        <property type="entry name" value="Cyclophilin-type_PPIase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002130">
        <property type="entry name" value="Cyclophilin-type_PPIase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044666">
        <property type="entry name" value="Cyclophilin_A-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45625">
        <property type="entry name" value="PEPTIDYL-PROLYL CIS-TRANS ISOMERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45625:SF4">
        <property type="entry name" value="PEPTIDYLPROLYL ISOMERASE DOMAIN AND WD REPEAT-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00160">
        <property type="entry name" value="Pro_isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001467">
        <property type="entry name" value="Peptidylpro_ismrse"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00153">
        <property type="entry name" value="CSAPPISMRASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50891">
        <property type="entry name" value="Cyclophilin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00170">
        <property type="entry name" value="CSA_PPIASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50072">
        <property type="entry name" value="CSA_PPIASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6 8" id="KW-0413">Isomerase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0697">Rotamase</keyword>
    <feature type="domain" description="PPIase cyclophilin-type" evidence="7">
        <location>
            <begin position="10"/>
            <end position="157"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002388"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038147"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU363019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OBZ88753.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="158" mass="17437" checksum="9240D957D8B9A7FB" modified="2016-11-30" version="1">MTDGRSVILDTSMGSIHIELYWDHAPRTCKNFYELAKQGYYDGVSFHRIIADFMIQGGDPTGTGRGGSSIYGEKFADEIHPQLKHTGAGILSMANAGPNTNGSQFFITLAPTPWLDGKHTIFGRVSDGMNVVKRMGLVRTDASDRPKDTVRIEKCRLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NI50</accession>
    <name>A0A1C7NI50_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 14">Coatomer subunit beta</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13 14">Beta-coat protein</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="20" type="primary">copb1</name>
        <name evidence="20" type="ORF">A0J61_03169</name>
    </gene>
    <organism evidence="20 21">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="20 21" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="20 21">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12 14">The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2 14">Oligomeric complex that consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="14">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1 14">Golgi apparatus membrane</location>
            <topology evidence="1 14">Peripheral membrane protein</topology>
            <orientation evidence="1 14">Cytoplasmic side</orientation>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="14">Cytoplasmic vesicle</location>
            <location evidence="14">COPI-coated vesicle membrane</location>
            <topology evidence="14">Peripheral membrane protein</topology>
            <orientation evidence="14">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="20">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000132">
        <property type="protein sequence ID" value="OBZ88781.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NI50"/>
    <dbReference type="FunCoup" id="A0A1C7NI50">
        <property type="interactions" value="832"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NI50"/>
    <dbReference type="InParanoid" id="A0A1C7NI50"/>
    <dbReference type="OrthoDB" id="10261439at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030126">
        <property type="term" value="C:COPI vesicle coat"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005198">
        <property type="term" value="F:structural molecule activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006888">
        <property type="term" value="P:endoplasmic reticulum to Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006891">
        <property type="term" value="P:intra-Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.10.10:FF:000444">
        <property type="entry name" value="Coatomer subunit beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002553">
        <property type="entry name" value="Clathrin/coatomer_adapt-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011710">
        <property type="entry name" value="Coatomer_bsu_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016460">
        <property type="entry name" value="COPB1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029446">
        <property type="entry name" value="COPB1_appendage_platform_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10635">
        <property type="entry name" value="COATOMER SUBUNIT BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10635:SF0">
        <property type="entry name" value="COATOMER SUBUNIT BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01602">
        <property type="entry name" value="Adaptin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07718">
        <property type="entry name" value="Coatamer_beta_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14806">
        <property type="entry name" value="Coatomer_b_Cpla"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005727">
        <property type="entry name" value="Coatomer_beta_subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="15" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5 14" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="11 14" id="KW-0968">Cytoplasmic vesicle</keyword>
    <keyword evidence="7 14" id="KW-0931">ER-Golgi transport</keyword>
    <keyword evidence="9 14" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="10 14" id="KW-0472">Membrane</keyword>
    <keyword evidence="8 14" id="KW-0653">Protein transport</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 14" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Clathrin/coatomer adaptor adaptin-like N-terminal" evidence="17">
        <location>
            <begin position="20"/>
            <end position="512"/>
        </location>
    </feature>
    <feature type="domain" description="Coatomer beta subunit C-terminal" evidence="18">
        <location>
            <begin position="672"/>
            <end position="806"/>
        </location>
    </feature>
    <feature type="domain" description="Coatomer beta subunit appendage platform" evidence="19">
        <location>
            <begin position="812"/>
            <end position="938"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="494"/>
            <end position="516"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="15">
        <location>
            <begin position="643"/>
            <end position="674"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="16">
        <location>
            <begin position="499"/>
            <end position="512"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00017024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00025536"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00030841"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PIRNR" id="PIRNR005727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF01602"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="Pfam" id="PF07718"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="Pfam" id="PF14806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="OBZ88781.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="946" mass="106529" checksum="5ADCD84CF10B2616" modified="2016-11-30" version="1">MATDLCYTLVYQDDTADTPSLQEFQRAFEKGPDETRIETMKKLLVIMLNGDPMEKLLLHVIRFVLPSRNKQLKKLLQFYWEICPKTKPDGKLKDEFILVCNALMNDLQHPNEYIRGSTLRFLCKIKEAEVLEPLVPSVRACLEHRHSYVRKNAVFAIGAMYKAFDYLFPDAPEVVHEFLLSEADMTCRRNAFAVLVSVDQPLAVEYLLQIIDSVPTFDELLQLAVIELIRKDSKNSAANKAAYIRCLSELLTAASHSVKYEAAAILLYLTTSPAAIKAAASCYIELIVKESDNNVKLIVLDRLEEIKNKHERVLDDLVMDILQVLTSPDIEVRRKAIMIVLDMVSSRNVQEVVLFLKKELSKTQDDAYEKNAEYRQLLIQSIHTCAIKFSEVAANVVHVLMEFLGDSNNPAAVDVVAFVREVVEKFPGLRESILERLLDTFSEMKSGKVFRGALWIIGEYCESLKEIDDAWKQIRHTLGEIPLLASEQKLLDATEAAEEQQQPQETQKSQPSAPRRILADGTYATESAYTESSASASRLEAVKQAKKPPLRSLLLAGDYFLSTVLSTALTKLVLRYSKLTDAQTANARKAEAMLIMTSILRIGQSKFVSFEIDEDSYDRIMQDLRVVGMANDHVNTVYLENTRQVYSRQLQAEEKRLQDAKQEAEANVQVQADDAILFRQFSKKTGGITDEYEQDLSRATGLSDDKDDLMSKLNRIVQLTGFSDKVYAEAVVNVHQYDILMDVLIVNQTNETLQNLTVEFATLGDLKLVDRPATHNLAPHSFLTVKAPIKVSSTETGVIFGNIVYDSHGASENCVILNDVHIDIMDYINPAYCNETQFRSMWTEFEWENKVNVNTNVSDLRAYLQHIMDSTNMSCLTPKKQLEGDCGFLSANMYARSIFGEDALANLSIEKTSDGPITGHIRIRSKTQGIALSLGDKITLAQKVTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NID7</accession>
    <name>A0A1C7NID7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">RING finger protein B</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">rngB_0</name>
        <name evidence="6" type="ORF">A0J61_04843</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000246">
        <property type="protein sequence ID" value="OBZ87114.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NID7"/>
    <dbReference type="STRING" id="101091.A0A1C7NID7"/>
    <dbReference type="InParanoid" id="A0A1C7NID7"/>
    <dbReference type="OrthoDB" id="2254818at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12087">
        <property type="entry name" value="TM_EGFR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.80">
        <property type="entry name" value="Kelch-type beta propeller"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011043">
        <property type="entry name" value="Gal_Oxase/kelch_b-propeller"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015915">
        <property type="entry name" value="Kelch-typ_b-propeller"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46093">
        <property type="entry name" value="ACYL-COA-BINDING DOMAIN-CONTAINING PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46093:SF18">
        <property type="entry name" value="FIBRONECTIN TYPE-III DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24681">
        <property type="entry name" value="Kelch_KLHDC2_KLHL20_DRC7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50965">
        <property type="entry name" value="Galactose oxidase, central domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117281">
        <property type="entry name" value="Kelch motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0880">Kelch repeat</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008889714" evidence="5">
        <location>
            <begin position="25"/>
            <end position="536"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="421"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="499"/>
            <end position="536"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="499"/>
            <end position="529"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OBZ87114.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="536" mass="59827" checksum="5193713E83CCA6D2" modified="2016-11-30" version="1">MLNKKKLLSCLLYVTIVLTIETLAIEVQPRRAADCAYLSNKIYCYGGYVKGSSDDDSLIMLDLNKNDGKPFGNLINQWENVTPVSNRIVFGRRAFAQAVALPDGKSMMVQGGYNYQSTSIEDQTIVYNAETNAWSIQPNYYEPQNGGNRQIYYGTGVYVDSINSIAFYGGYQQHVQNGTDYVKPDGTKISGLTFNNSDGYINSFAGFYYLTLYDLYKNTWSVPAQTGTPTSYRISQTATYVPLSKKIYYFGGQYYNTTDSRLYNAYMDYVITYDTVSSSWKYVYSTSNRSPSQRTMHSTTLLSDGYNILLYGGTFDGTVALMDYCYTFNIQTAEWTFHNLVAPAGTSAPRSHHSAVMIDNSTLGIFFGIDKAGNPTNDLLIMDVRDVNQLSFSDTYPINTNLTTSSTNTTSSNDSTSGNSATIGIAVGVSCGALAIIAAIVFYVLRKRKQRSRHQVTQVSNNNHLHPETEMLEVDWDKIDGQYYNQVDPPQQFVQLRSQSQITTQTPNEYPSPEGSSRHNVSPTMTVTYTKPDIGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NKT3</accession>
    <name>A0A1C7NKT3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Eukaryotic translation initiation factor 3 subunit M</fullName>
            <shortName evidence="5">eIF3m</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">A0J61_02857</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Component of the eukaryotic translation initiation factor 3 (eIF-3) complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the CSN7/EIF3M family. CSN7 subfamily.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the eIF-3 subunit M family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000114">
        <property type="protein sequence ID" value="OBZ89096.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NKT3"/>
    <dbReference type="FunCoup" id="A0A1C7NKT3">
        <property type="interactions" value="756"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NKT3"/>
    <dbReference type="InParanoid" id="A0A1C7NKT3"/>
    <dbReference type="OrthoDB" id="10267031at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016282">
        <property type="term" value="C:eukaryotic 43S preinitiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033290">
        <property type="term" value="C:eukaryotic 48S preinitiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071541">
        <property type="term" value="C:eukaryotic translation initiation factor 3 complex, eIF3m"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001732">
        <property type="term" value="P:formation of cytoplasmic translation initiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03012">
        <property type="entry name" value="eIF3m"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045237">
        <property type="entry name" value="COPS7/eIF3m"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027528">
        <property type="entry name" value="eIF3m"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040750">
        <property type="entry name" value="eIF3m_C_helix"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000717">
        <property type="entry name" value="PCI_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15350">
        <property type="entry name" value="COP9 SIGNALOSOME COMPLEX SUBUNIT 7/DENDRITIC CELL PROTEIN GA17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15350:SF2">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18005">
        <property type="entry name" value="eIF3m_C_helix"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01399">
        <property type="entry name" value="PCI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00088">
        <property type="entry name" value="PINT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50250">
        <property type="entry name" value="PCI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 5 7" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="4 5" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PCI" evidence="6">
        <location>
            <begin position="143"/>
            <end position="346"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008482"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50250"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OBZ89096.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="400" mass="44512" checksum="8D8045020F48752C" modified="2016-11-30" version="1">MSINNIFVQGGAESQIIDLAIYISKLRDEEGEKEAPYVKHIESILKSDKKDAVYAEIAKDASILLTEGDREVEGAFNLLIVTVLNAPEAVLSNTVQLLVDTLTKTESNKISLKQKILLNLYNALPGNSPIRYHAFVGLVEATSQAEELESLYGQLEYVDAWAKQWGIDQSTQRELYNYLSQVLLKAGEEKLALDFSLKTLVTLGEDKEAEKLAKDIVRRAIAMENYFAFEDLVQYTAIQKLKGTPEYELLDIFLNGTLSTYQAFEKANGSVIDHAENNTHKIRLLSLASLGSENLSRELTYAEIANSLQIPVEEVEMWVIDVIRAGLVEAKLDQLNKTVIVHRSIYRVFGKEQWKKLSTSLSAWKENLNEILAVIGNAKLIAGGALQGQSSVVVETTDAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NLF0</accession>
    <name>A0A1C7NLF0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Folliculin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">FLCN</name>
        <name evidence="4" type="ORF">A0J61_02109</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000076">
        <property type="protein sequence ID" value="OBZ89828.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NLF0"/>
    <dbReference type="FunCoup" id="A0A1C7NLF0">
        <property type="interactions" value="347"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NLF0"/>
    <dbReference type="InParanoid" id="A0A1C7NLF0"/>
    <dbReference type="OrthoDB" id="5599713at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1904263">
        <property type="term" value="P:positive regulation of TORC1 signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037521">
        <property type="entry name" value="FLCN/SMCR8_DENN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021713">
        <property type="entry name" value="Folliculin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037520">
        <property type="entry name" value="Folliculin/SMCR8_longin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31441:SF2">
        <property type="entry name" value="FOLLICULIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31441">
        <property type="entry name" value="FOLLICULIN FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11704">
        <property type="entry name" value="Folliculin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51834">
        <property type="entry name" value="DENN_FLCN_SMCR8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008889773" evidence="2">
        <location>
            <begin position="23"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="domain" description="UDENN FLCN/SMCR8-type" evidence="3">
        <location>
            <begin position="189"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="45"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="108"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="313"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="391"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="45"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="119"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="327"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51834"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OBZ89828.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="423" mass="46678" checksum="44209CC62337538E" modified="2016-11-30" version="1" fragment="single">LLCAFKTMNALIALLHFCEVHGPCVVYCTQAIHNNNMAIANPATTAPTTNNNISKPTTTTSNLASATNPTATASDSDMTESANSAIVNAKSMEEAHITPPLKTQPIPISRPVAHHPPQTSSVTSFSTTPSSSMRKNSISSLSAGAPNNTGIAFPSYSSSSNSSSSCSNCAACTAQLPLVNNGQGMTEVKRLVTLDQDDPSIQYIGTTKSPQQPHLYKAVRLACVRSLTAEFCQGRDGPVLFGDDENGYVMSYMFKLRDSQARGEARFYSLIMLMTDRVYLVSCWPFLVSAFRSMASNLQERANVVFQREKESMRHSSITHNSRRAPISSQDTMSNSLHFPQKKKDQFYRRRSNTALRSLVDLLGIKDIYAQIQAQFSYTLKLSSRKRMEKLTQGRRESPFYTQLKAQYEAKKQSESSRTSQIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NLH6</accession>
    <name>A0A1C7NLH6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 10">Mitochondrial escape protein 2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">yme2</name>
        <name evidence="14" type="ORF">A0J61_01995</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9 10">Plays a role in maintaining the mitochondrial genome and in controlling the mtDNA escape. Involved in the regulation of mtDNA nucleotide structure and number. May have a dispensable role in early maturation of pre-rRNA.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 10">Mitochondrion inner membrane</location>
            <topology evidence="1 10">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the YME2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000070">
        <property type="protein sequence ID" value="OBZ89957.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NLH6"/>
    <dbReference type="FunCoup" id="A0A1C7NLH6">
        <property type="interactions" value="8"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NLH6"/>
    <dbReference type="InParanoid" id="A0A1C7NLH6"/>
    <dbReference type="OrthoDB" id="10267654at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018850">
        <property type="entry name" value="Mt_escape_2_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039627">
        <property type="entry name" value="Yme2_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32198">
        <property type="entry name" value="MITOCHONDRIAL ESCAPE PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32198:SF2">
        <property type="entry name" value="MITOCHONDRIAL ESCAPE PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10443">
        <property type="entry name" value="RNA12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 10" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5 10" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="10" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="Mitochondrial escape protein 2 C-terminal" evidence="13">
        <location>
            <begin position="361"/>
            <end position="801"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="514"/>
            <end position="536"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="11">
        <location>
            <begin position="775"/>
            <end position="802"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="514"/>
            <end position="529"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010320"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00020222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00025276"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU367108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF10443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="OBZ89957.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="869" mass="98780" checksum="9AA43A02F8C673CA" modified="2016-11-30" version="1">MLSRIQTRTWSSRRSCTILSKQQSSCFQTNFSPRIRSFKTFSAHLQAGEGKIAIDKSSLEGSYSQQTAQLYLDNVFPLKVHSFDIRQMFFRDSKSFLESKAHQAIPSDDLPYEFAIKEIIARTKDGGAIVTFTFKSTDGQKLNVAKEIVDKINHHVTTNNIVAPFNFQSVRAFLVKGQPFLEDILARYPTQRLRIEFQGPAVHVETLYHQLRPYGKLFDLAIYPNPITAKDPARYAMAYFTRMRHATSARNCLHGHVVEGTRLNVLYERQLRTNVVKDWLVNHPRITVPAVAAIFAGITYVVFDPIRVFFITSKVTQRFNPEEYALYRWLRRETWARLLPVGASRDVAMEQSQSLWADDVEKIEKLKSWLAESPETFVLITGHKGSGKSALVKSAIQDRKNKLFIDCEELATARNQSEMTKGLAKEVGYFPVFTWAASMSGMFDTMIAATTGQKTSFSSSPDSQMKDILETVAIALREIVPNEKEARRRAEENKHHVTLLSHIKHVVLDLIGKEDTPEKTRSNHPQDGEKEGDDSDELTEKLIPIVVIDNYMYRETAKNAKLWEELAEWASLLIENEIAHVVFVSSNAGVMKTLGKALPGKSFSSIALSDAPLEMAMSFIKKQLDSEIDDPELPKVVSALGGRLTELELLVQKMKMNMDAKTAFEDIVARNLIEIRKYGFGDSTECDSKLEWTAPQFWTIVKLLSEKKHINYDELKWSPVFNGSEGPLKAMERAELIIIVQKEGRSHSIRPGKPVYYTVFDRLMADTIFNASMEIESNMALKKQSEENMAKLEDNINKLTHINAPSKLPKEIEARVQFLLTKVASCQKSIEEYDTNIKKAKEIITQAWAEELSGPSQPKQEKKRGFFFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NLI7</accession>
    <name>A0A1C7NLI7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">TFIIB-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_01976</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000069">
        <property type="protein sequence ID" value="OBZ89993.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NLI7"/>
    <dbReference type="InParanoid" id="A0A1C7NLI7"/>
    <dbReference type="OrthoDB" id="2220037at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.25.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57783">
        <property type="entry name" value="Zinc beta-ribbon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ89993.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="418" mass="47922" checksum="607123488B52EE80" modified="2016-11-30" version="1">MSCPNCKSTQTDVNELDGSICCLQCGTVIEDALLRETFEESANYVPAMSRQKAGNHSRLLSTFSKAAVFFGLPEDLVETGKELCREFISKSTTTFLNEVAVYIAFIVSREWKSEWNLMDFVEAFPIPLYLPQVYRTRNVLKGSINAHWRTPQEELNHFIVRIYPLVVKQVYRDHSRPKPLSLSELKSKTRALLDLGSAYCLNTAKKARPLMVVTALIAGLSIRVTNPANYPKRSKMISARRRLCFSEFTSVCFSSKVSLSTRYDEYLDLLFACASCIPWIKKVEKSYVHYYLDDILSSFGTKTPILVLPLDRFAVRSFQRNQQMRKFIETSTEEAKQCLREQTEPNDKSSIAYAIYSLLQFGFQEHQIVGFNEAYIRNMAHSLLLRNLASGSDVQLDLDREEVDEKDMSDKEIEIYLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NLW2</accession>
    <name>A0A1C7NLW2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_03688</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000163">
        <property type="protein sequence ID" value="OBZ88264.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NLW2"/>
    <dbReference type="STRING" id="101091.A0A1C7NLW2"/>
    <dbReference type="InParanoid" id="A0A1C7NLW2"/>
    <dbReference type="OrthoDB" id="2272836at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="105"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="139"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="61"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="8"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="110"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="208"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="266"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="294"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="311"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="352"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="377"/>
            <end position="391"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ88264.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="391" mass="42502" checksum="5C9EC93CE053553C" modified="2016-11-30" version="1">MANPSPHPGSTSPKQPTSAFQWPVPPSPSQSKSTLSNDITVKEILDRYSDDPELLKYILTAKSEEDKKKAARDTLRAEEARIKLRQMDLDLAREQAKTGDMVTPIQVLPHPLPPPPIPPPSSQPYIGLAPVQQQVLARFNYPPHYQQAPPLSPSVPYPHSAHPLCPSTDTTRLQPHPAPFRPISPTLEEPKGSKHRSSISLPSEQQEPPDKLSHNKVMEALKAKIQRGAGGPPSPLTTSPMTRPPLPSENKKRKPTLPRPVLIEQPSSSKSTSPSPRSAKPILPPIDTSLGRMENVHARQEKPINNHHNHSNPNNNNNSSSSSSSSSSSSNSSSSNSHSNNNPHPSKRSRIDTNATRTVSAPSPSDLVLLNTRRARSLSPPSSSSSTKDAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NLZ7</accession>
    <name>A0A1C7NLZ7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_01761</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000060">
        <property type="protein sequence ID" value="OBZ90173.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NLZ7"/>
    <dbReference type="InParanoid" id="A0A1C7NLZ7"/>
    <dbReference type="OrthoDB" id="2270565at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="33"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="33"/>
            <end position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ90173.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="210" mass="24144" checksum="94E40F7CA1D9EBBE" modified="2016-11-30" version="1">MIACTSMPLLSVRPLVAQSSRYVNNLKRYYSSHDDRKEKKLQKEPLSKPNVQKLTDPPPNVPSFMPVVNIPVDELAHSAFYSLHRPLFGLSTPRPFLAGDMVGQIKKEEKDAFSEEALVQYMMTLKPFEPPQLDSIAKEEEKCSTTTLTVEIDPSYFLNHNNNHDEIADYLTAMQEKLSLLYDERTAAKNTIPKKRARRLRKRKGFFDKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NMF2</accession>
    <name>A0A1C7NMF2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein C23H4.21</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_01676</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000056">
        <property type="protein sequence ID" value="OBZ90267.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NMF2"/>
    <dbReference type="STRING" id="101091.A0A1C7NMF2"/>
    <dbReference type="InParanoid" id="A0A1C7NMF2"/>
    <dbReference type="OrthoDB" id="5576875at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025124">
        <property type="entry name" value="Gag1-like_clamp"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13259">
        <property type="entry name" value="clamp_Gag1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Gag1-like clamp" evidence="1">
        <location>
            <begin position="48"/>
            <end position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13259"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ90267.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="95" mass="11184" checksum="01F061BA07A06EF1" modified="2016-11-30" version="1">MTTDQSKGLVAWEARRKQWTTPIPDVQKNSAEMSNRLEELVQHEDQRKTIYKQLVYQRQAFRHPIPLKLVIPILITGWQEDGLWPKGMLVQDKSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NMG3</accession>
    <name>A0A1C7NMG3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_01670</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000056">
        <property type="protein sequence ID" value="OBZ90265.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NMG3"/>
    <dbReference type="InParanoid" id="A0A1C7NMG3"/>
    <dbReference type="OrthoDB" id="1897642at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47232">
        <property type="entry name" value="TRANSDUCIN FAMILY PROTEIN / WD-40 REPEAT FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47232:SF1">
        <property type="entry name" value="TRANSDUCIN FAMILY PROTEIN _ WD-40 REPEAT FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="223"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="36"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="52"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="75"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="92"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="104"/>
            <end position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ90265.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="637" mass="72343" checksum="8005CA62E37C0C40" modified="2016-11-30" version="1">MDRESLLPRSLFSASTLKRENAEESLASLLSQPQPQKRRRRSLSQHRRSPTRGDSTVLVESNNNLRSNQTQEPVIFEDVDDSENDNNDNNEHSNNSSSSSSSSSDEDEGDNNDIESTMLRQDNISSAHINHTMHHLLLKLERQQSKQNKYIEKXKHINKSIKKTNRLITYNANQLMQAVNSNNYNSPVPKQTTKPPLALAKRSAPLPPVNPAKNNVAVISDDDMQEQQSNKPNLTVDPPSRTRKSTNRPPFPAPVKITPVRKVFKEIDLAQSSKIDIFTPRQKKGETAFKKKPRSLLYNIANENTPRGISELMITTSMDGELHFWNAQERKKIKTIGSDHLYDTWIDDICWATPSTLAFCPPQKSEEPVKLIHIGKTSRSNVEGRIQSLDDSPHDSGISVIQSLDTGDNNTQYVEKCSFLTGGYDKSVYIWNLKRESPDDNFTTSEVNRLNLKHTSYLLSLCYDKYRSNLFSGGADERLVIFDLQTDSTIREMRLSQRVNQINQSKANPNLMLITLSSCVDQFSVYDQRCPGYDGIKLRFGQHENENLSRYIKLDMHDNGYTVCCGSQSSSKLNFWDLRYTGVSRNISFSMETPSTSKILIPKFIPNSNTIVSVSSTRTLSWLDYQVKKDEIVKTLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NN14</accession>
    <name>A0A1C7NN14_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Putative transporter C4B3.13</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">SPCC4B3.13</name>
        <name evidence="7" type="ORF">A0J61_01434</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000045">
        <property type="protein sequence ID" value="OBZ90531.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="FunCoup" id="A0A1C7NN14">
        <property type="interactions" value="113"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NN14"/>
    <dbReference type="InParanoid" id="A0A1C7NN14"/>
    <dbReference type="OrthoDB" id="2126698at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015297">
        <property type="term" value="F:antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042910">
        <property type="term" value="F:xenobiotic transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990961">
        <property type="term" value="P:xenobiotic detoxification by transmembrane export across the plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd13132">
        <property type="entry name" value="MATE_eukaryotic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045069">
        <property type="entry name" value="MATE_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002528">
        <property type="entry name" value="MATE_fam"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00797">
        <property type="entry name" value="matE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11206">
        <property type="entry name" value="MULTIDRUG RESISTANCE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01554">
        <property type="entry name" value="MatE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="108"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="138"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="172"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="202"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="255"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="285"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="328"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="370"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="400"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="426"/>
            <end position="451"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OBZ90531.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="469" mass="51291" checksum="7362C8B0EB121D72" modified="2016-11-30" version="1">MSETIPILNNNLDKEQIGYQYELRWLIKNAMPLVVSYLLQNSLQSISIITVGHLGSTELASATLGSMFVTISGLSIATGATLSLDTLCSQSFTSAEDKTVVGLHVQRCLAFMSLLYIPLIALWWYAESIFLLLRQDPVVAQLAGTXVRWMILAAPAFALFESLKKLLQAQGLFRAPTVVLLIVTPINLLLNYALVHMTGWSLGFYGAPIASCISYWLIVVLMSLYIIRIDGYQAWPAWSTRAAYDMSHWKPMIKLAIPGILLICTESWAYEIIALGASWVDTTNLGAQSVILTSITALYTLAFGVGIASANRVGNLLGAQQPRQARRAAHTALCVGTAVGLANAMTLLIFRHTWASIFTDDPQVTNLVTQVLPLVATFVFADNIAGVADGVLNGMGRQHVGAICNIGAYYFSALPIGFYLCFNRKWQLIGLWTALAGSLIVACLYTVVVLLCSNWRKEAEKAEERSKDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NN27</accession>
    <name>A0A1C7NN27_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_01465</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000047">
        <property type="protein sequence ID" value="OBZ90485.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NN27"/>
    <dbReference type="InParanoid" id="A0A1C7NN27"/>
    <dbReference type="OrthoDB" id="2108430at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12874">
        <property type="entry name" value="zf-met"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="2">
        <location>
            <begin position="47"/>
            <end position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ90485.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="420" mass="47945" checksum="93356749FB0836A9" modified="2016-11-30" version="1">MLPLYDAGLDASNYNILQPLKEILPYDLPKCSSEQPAATNKQPEKDGYCKACKKKFNNETTYQNHLKSAKHIANQKKTVQKTATQPKIPVHPQVQEALQQLQVADTSKDPTVAIQIYWTQAQILYQLKRPQHTERALSSLIGLLSSQPAGLTLTSAQVTYYLYNSQLALARLYCLYQQLEKAWSFYLDGLNTKWKIDRVELLKLAQEIRFCSLDQLLTSCDTLATKYLTRERNRTKPAPVLSDRNNAFSIILNEAGNLFAQQDQLFMQVPVEHIAIVFYGLGSLVCSFEPSIGFSSNDFYFILSNVYHSLGWLHRVIDVKLLDRQDTWHVLDAFLMSLEIDDLVRARAVEAYFKESIYPDVQLVCQLCQAKCTLQSVPTLSFQLDHISLLLEQTTEPLLIRTQSKQDQAQFLARVRDLIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NN87</accession>
    <name>A0A1C7NN87_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">37S ribosomal protein S8, mitochondrial</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">MRPS8</name>
        <name evidence="4" type="ORF">A0J61_01338</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uS8 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000041">
        <property type="protein sequence ID" value="OBZ90612.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NN87"/>
    <dbReference type="FunCoup" id="A0A1C7NN87">
        <property type="interactions" value="187"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NN87"/>
    <dbReference type="InParanoid" id="A0A1C7NN87"/>
    <dbReference type="OrthoDB" id="409928at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005763">
        <property type="term" value="C:mitochondrial small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1490.10:FF:000005">
        <property type="entry name" value="Mitochondrial 40S ribosomal protein S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1370.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000630">
        <property type="entry name" value="Ribosomal_uS8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035987">
        <property type="entry name" value="Ribosomal_uS8_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11758">
        <property type="entry name" value="40S RIBOSOMAL PROTEIN S15A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00410">
        <property type="entry name" value="Ribosomal_S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56047">
        <property type="entry name" value="Ribosomal protein S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OBZ90612.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="153" mass="17218" checksum="5CAB6A10D70AF020" modified="2016-11-30" version="1">MPRVHDLCARIQNGFRARLQSIAIPETKMNLAISNILYREGFLTSVTRGDHVAPDNSYTPTTNENVATRRIWINLKYKENLPALSRLNLVSKPSKKVYFTVNELKNITNGRRAQYIKPLQPGEIAIVNTNRGVLEVNEAIEKNVGGEVICRAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NNS4</accession>
    <name>A0A1C7NNS4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">START domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_01180</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000034">
        <property type="protein sequence ID" value="OBZ90772.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NNS4"/>
    <dbReference type="STRING" id="101091.A0A1C7NNS4"/>
    <dbReference type="InParanoid" id="A0A1C7NNS4"/>
    <dbReference type="OrthoDB" id="196858at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008289">
        <property type="term" value="F:lipid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00177">
        <property type="entry name" value="START"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.530.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041036">
        <property type="entry name" value="GH5_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023393">
        <property type="entry name" value="START-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002913">
        <property type="entry name" value="START_lipid-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051213">
        <property type="entry name" value="START_lipid_transfer"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19308">
        <property type="entry name" value="PHOSPHATIDYLCHOLINE TRANSFER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19308:SF14">
        <property type="entry name" value="START DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18564">
        <property type="entry name" value="Glyco_hydro_5_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01852">
        <property type="entry name" value="START"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55961">
        <property type="entry name" value="Bet v1-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50848">
        <property type="entry name" value="START"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="START" evidence="2">
        <location>
            <begin position="101"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="domain" description="START" evidence="2">
        <location>
            <begin position="422"/>
            <end position="619"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="336"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="776"/>
            <end position="803"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="353"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="363"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="781"/>
            <end position="790"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="791"/>
            <end position="803"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50848"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ90772.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="878" mass="98996" checksum="158509EEA8F40756" modified="2016-11-30" version="1">MSHSLAYAPFNQDTFPAEWEENQHPRNILKRPKEKTGRYNAIFSDDEDEGPVPQANLSSRLLHQHDNKTRTGYIDPALSSSTYHIHQADSALTTLKHALMDDDWKKALKHKSGVMVYMKNGVYRSDKTPIFKGEAIIYGFSPQSIFYVIGMRKLWDEQYEDGNLVENLNDTTSLTYESMKPTTTSKSRDLALVEKIECAQNGSILFACTSVETPRIPKVHGKTRASIKLQGWMLEPISFSESPPATKVTFVIQENMKGWVPGFAKKTLARRPLVIAKIAEYLERKAERMRAQSAPLGYNQRPSIVNPALLQHTRNKSSSSILLGPAPQNGVKKHISFAQKDTTYTPLSKEDKHEEEEEEEDVTNQSSSSGSHTVTPDTHVVTQRTTSLPEPKPASVSPKLPKAKAHLYPAHRHSIQKIRSLELLKRLTASKDLWNVMKQSNENSHITCYSLNRKLLVNQSDSHTKKDDVNESEAMSPFIRVDSTISGGWTPEQLCSMIHCFGARKKWDACFGDGKIIERFSQKDYLVHFICSSHLPMAQVDFAAISSIETDPASGTVYTAACSVVDPQIPSNTDHIRASSDICGWAFRPSFNQQGKVSKVDVSFVYHIDFRHQIPAPILQDWIQLSLQPIEHMKQYLTKNGCPPYIRRVAGKVVLETFDPVSNQYKLTIIAKHEPSDAYQARKKALSSKQKQLWCTDIRFHELMFPHGLDIQVEPHEMIQFQVTTKGHKCLKLFTTEQAMDGKQISLTMSPLSPKKSRDAHSYCYNGELFPPTPSVKPAASSINVSNTTTHSEKADKETKDEQLVEPTIQENTRKEMTENPVQVPKGYVLVPENPSTRNNMVIITDELSFNGQQLSVMFLAMVLCYYMGKLTSCHCPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NNX8</accession>
    <name>A0A1C7NNX8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_01785</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000061">
        <property type="protein sequence ID" value="OBZ90166.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NNX8"/>
    <dbReference type="InParanoid" id="A0A1C7NNX8"/>
    <dbReference type="OrthoDB" id="2290357at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="98"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="133"/>
            <end position="161"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ90166.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="195" mass="22553" checksum="B815BF4DF660D109" modified="2016-11-30" version="1">MNRESSYRMSAFYRRFYHSPSTVDSLSTSSLSTTSSSSSFEQIFSRLLDALIFTSAIAITAYSYLTGNLLTNTHSPNHSPPLIPLSAQDQSSVLHHHYHKHHRKSFSEQTEEDKRQRTQAWAEQHSLLPVKKRTCSNQLPHSRDQHLKREKKRTQSLPVNKIPKEEEDEVLLRMEERLKSMIQEGQEALSSPVKY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NP26</accession>
    <name>A0A1C7NP26_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Synaptobrevin 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">syb1</name>
        <name evidence="12" type="ORF">A0J61_01218</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Endomembrane system</location>
            <topology evidence="7">Single-pass type IV membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the synaptobrevin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000036">
        <property type="protein sequence ID" value="OBZ90730.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NP26"/>
    <dbReference type="FunCoup" id="A0A1C7NP26">
        <property type="interactions" value="227"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NP26"/>
    <dbReference type="InParanoid" id="A0A1C7NP26"/>
    <dbReference type="OrthoDB" id="190375at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016192">
        <property type="term" value="P:vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.5.110:FF:000004">
        <property type="entry name" value="Vesicle-associated membrane protein 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001388">
        <property type="entry name" value="Synaptobrevin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016444">
        <property type="entry name" value="Synaptobrevin/VAMP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042855">
        <property type="entry name" value="V_SNARE_CC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45701">
        <property type="entry name" value="SYNAPTOBREVIN FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00957">
        <property type="entry name" value="Synaptobrevin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005409">
        <property type="entry name" value="Synaptobrevin_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00219">
        <property type="entry name" value="SYNAPTOBREVN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF58038">
        <property type="entry name" value="SNARE fusion complex"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00417">
        <property type="entry name" value="SYNAPTOBREVIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50892">
        <property type="entry name" value="V_SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0653">Protein transport</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="98"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="domain" description="V-SNARE coiled-coil homology" evidence="11">
        <location>
            <begin position="34"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008025"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00046280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="OBZ90730.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="128" mass="14596" checksum="5C76807F3A5BD70F" modified="2016-11-30" version="1">MEFRGRYEKPKTLAQPYDPYVPNLSAGAGKENSKTSQVQKQVDEVVGIMQENIDKVVQRGERMDDLRGKTEDLQATAGHFRRGANQVRKRMWWKDLKWKIIIAVTILVILAIIIGSVVGTQTNKDQQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NQC1</accession>
    <name>A0A1C7NQC1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_00652</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000015">
        <property type="protein sequence ID" value="OBZ91317.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NQC1"/>
    <dbReference type="InParanoid" id="A0A1C7NQC1"/>
    <dbReference type="OrthoDB" id="10268014at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56059">
        <property type="entry name" value="Glutathione synthetase ATP-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ91317.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="538" mass="60119" checksum="850B5EE1CFCF077C" modified="2016-11-30" version="1">MTTSLGSPPLLPNDGLEKLSISTAETAPADKKIQTTPPKTPPSEIANPMGNEHHRGQTRLVSQGEFEPEQHFYPRVLNAQIHPLIQSFFTLGNERIIARYTHLNPQVKVEDLKEILSYSPKHFQWAGSDLFNVTTASGHRQMIVIETNSCPSGQKSMPLLSETDEHNEQGGYRNVIQSAFQDQLSKADPSLGGLAVICDKNMMESSGYAAVLADVAKEHVWLAEWHVDDPDPGIKWVDRVLYVRDKDQVWHPIRACFRYLTQKPWNRFPLKTKTIVMNQIISCLAGGRNKMMAARAYDFYNKDIVGTGLSIKTPETINNVTRGEIPLWISSMGGHAVLKVPYSNAGQGVYTITNQSELNDFMNQDHHYDKFIVQSLVGNASWSSVTTAGKFYHVGTIPNKKSNTYVSDLRMMVTGSAQGFRPICIYGRKARLPLAGDLPPDANTWDMLGTNLSVKLPDGGWTTDTSRLILMDRKDFNQLGLGIDDLIDAYIQTVLAVIAIDRMAIRLMAEGEFDYSLFESLNPDNALMNEIRQANEDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NQG8</accession>
    <name>A0A1C7NQG8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">DnaJ homolog 1, mitochondrial</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">mdj1_0</name>
        <name evidence="10" type="ORF">A0J61_00612</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000014">
        <property type="protein sequence ID" value="OBZ91353.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NQG8"/>
    <dbReference type="FunCoup" id="A0A1C7NQG8">
        <property type="interactions" value="469"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NQG8"/>
    <dbReference type="InParanoid" id="A0A1C7NQG8"/>
    <dbReference type="OrthoDB" id="10256793at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031072">
        <property type="term" value="F:heat shock protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042026">
        <property type="term" value="P:protein refolding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009408">
        <property type="term" value="P:response to heat"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd10747">
        <property type="entry name" value="DnaJ_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd10719">
        <property type="entry name" value="DnaJ_zf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.260.20:FF:000005">
        <property type="entry name" value="Chaperone protein dnaJ 1, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.10.230.10:FF:000001">
        <property type="entry name" value="DnaJ subfamily A member 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.230.10">
        <property type="entry name" value="Heat shock protein DnaJ, cysteine-rich domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.260.20">
        <property type="entry name" value="Urease metallochaperone UreE, N-terminal domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01152">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012724">
        <property type="entry name" value="DnaJ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002939">
        <property type="entry name" value="DnaJ_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018253">
        <property type="entry name" value="DnaJ_domain_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008971">
        <property type="entry name" value="HSP40/DnaJ_pept-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001305">
        <property type="entry name" value="HSP_DnaJ_Cys-rich_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036410">
        <property type="entry name" value="HSP_DnaJ_Cys-rich_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF008035">
        <property type="entry name" value="PRK10767.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43096">
        <property type="entry name" value="DNAJ HOMOLOG 1, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43096:SF52">
        <property type="entry name" value="DNAJ HOMOLOG 1, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01556">
        <property type="entry name" value="DnaJ_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00684">
        <property type="entry name" value="DnaJ_CXXCXGXG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00625">
        <property type="entry name" value="JDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57938">
        <property type="entry name" value="DnaJ/Hsp40 cysteine-rich domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49493">
        <property type="entry name" value="HSP40/DnaJ peptide-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00636">
        <property type="entry name" value="DNAJ_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51188">
        <property type="entry name" value="ZF_CR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0143">Chaperone</keyword>
    <keyword evidence="1 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 7" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 7" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="J" evidence="8">
        <location>
            <begin position="45"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="domain" description="CR-type" evidence="9">
        <location>
            <begin position="176"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="CR-type" evidence="7">
        <location>
            <begin position="176"/>
            <end position="256"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00072890"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00546"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51188"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OBZ91353.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="402" mass="43963" checksum="ED97E2375BFFFC6A" modified="2016-11-30" version="1">MLRTLLKTRLPIIHQDIQSSAIGLFPFSCYKKGFHTTHSARHIQDPYKILGISRSSSQNDIKKAYYKLAKQYHPDTNKDKKAREKFVQIQEAYEMLSDEEKRKQYDQFGHHDRSGGAKGFYSSSGFDPNDIFSQFFGGGFGDAGFGSAAGGDPFRTTSGEDIQVPLTIDFMEAVKGVTKTITVQSVTHCPTCQGSGLRAGHAKSSCHLCHGTGFQAIQMGGFHMQSTCQACGGLGQSIPPNAQCPTCQSAGKVRENKQVQVTIPAGVDNHSRIRVPGAGDAPLKGNGPHGDLFVSLNIKPSPVFRRQDADIFCDAKIPFYKAMLGGKVRIPTIDGDVELRIPPGSQPQDSIALRGRGIQRLKGSSRGDQIVQLKIELPRSLQDKQRDIIKKYAALVDEKPSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NR38</accession>
    <name>A0A1C7NR38_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">ATP-dependent RNA helicase</fullName>
            <ecNumber evidence="14">3.6.4.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="19" type="primary">SPB4</name>
        <name evidence="19" type="ORF">A0J61_00343</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="19 20" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19 20">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="14">RNA helicase.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11 14">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.13"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="14">The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the DEAD box helicase family. DDX55/SPB4 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="19">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.13" evidence="14"/>
    <dbReference type="EMBL" id="LUGH01000007">
        <property type="protein sequence ID" value="OBZ91605.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NR38"/>
    <dbReference type="FunCoup" id="A0A1C7NR38">
        <property type="interactions" value="1058"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NR38"/>
    <dbReference type="InParanoid" id="A0A1C7NR38"/>
    <dbReference type="OrthoDB" id="7396459at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030686">
        <property type="term" value="C:90S preribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005654">
        <property type="term" value="C:nucleoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030687">
        <property type="term" value="C:preribosome, large subunit precursor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902626">
        <property type="term" value="P:assembly of large subunit precursor of preribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000470">
        <property type="term" value="P:maturation of LSU-rRNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd17960">
        <property type="entry name" value="DEADc_DDX55"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18787">
        <property type="entry name" value="SF2_C_DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000877">
        <property type="entry name" value="RNA helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056330">
        <property type="entry name" value="CTT_SPB4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000629">
        <property type="entry name" value="RNA-helicase_DEAD-box_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014014">
        <property type="entry name" value="RNA_helicase_DEAD_Q_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025313">
        <property type="entry name" value="SPB4-like_CTE"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24031">
        <property type="entry name" value="RNA HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13959">
        <property type="entry name" value="CTE_SPB4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23681">
        <property type="entry name" value="CTT_SPB4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01178">
        <property type="entry name" value="DUF4217"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00039">
        <property type="entry name" value="DEAD_ATP_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51195">
        <property type="entry name" value="Q_MOTIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 13" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6 13 19" id="KW-0347">Helicase</keyword>
    <keyword evidence="5 13" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 13" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="8 14" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3" id="KW-0698">rRNA processing</keyword>
    <feature type="domain" description="DEAD-box RNA helicase Q" evidence="18">
        <location>
            <begin position="11"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="16">
        <location>
            <begin position="42"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="17">
        <location>
            <begin position="257"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="546"/>
            <end position="637"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Q motif" evidence="12">
        <location>
            <begin position="11"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="15">
        <location>
            <begin position="576"/>
            <end position="586"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="15">
        <location>
            <begin position="607"/>
            <end position="616"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00038002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00047984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU000492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU365068"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS51195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="OBZ91605.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="637" mass="72824" checksum="EF5F449EA28B6159" modified="2016-11-30" version="1">MSAVPTQAGSWRTLETPLSDPILTTLDTMGFDTMTPVQAGVIPLFLKNKDVVVEAVTGSGKTLSFVIPIIEKLLRREHTLKNQEIGAVVITPTRELAQQIHSVFQLFVQDHEREEQIRLGLFIGGTSSLAEDIATFKQDHPRILIGTPGRLEELVTKTGQLVNTKELEILVMDEADRLLDMGFSKQLSNIISHLPKQRRTGLFSATMTDAISELVRAGLRNPVRIVVKVEDLNNKGNVQRTPSTLDIDYLVCDADQKLLQMKRILESELADEDGARKFIVYFATCAMVDYFYKILVRLQSLKSFSFHSLHGQMDTKRRSATYKAFTELSPAIPAVLLCTDVASRGLDVSDLDYVIQVDPPQDPKAFSHRCGRAGRAGRKGRATALLVRGREEVYVDFLKLRKIPLQRRPYIMADYSLFDNQARNTTEENDKTTSIQVEDGSLPSLIQEVRSIVKTDRDLHDRAMKAFVSWARAYSKHEASYIFRLKDLDLGKLAMGFGLLKLPKMPELKSQPETAFEEEKDIDWDTYKYTDKMREAKRLRELKEYQEKMKQPKPSQNPKKKGTVAWSDKIEAKERKQVRKEKKHAKKEYLKKQAQLEVENKKRQLEEEQEDLEELEQDYKKVKKGRSSKNTDFDELL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NRE5</accession>
    <name>A0A1C7NRE5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Chaperone protein DnaJ</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">dnaJ_3</name>
        <name evidence="4" type="ORF">A0J61_02125</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000076">
        <property type="protein sequence ID" value="OBZ89824.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NRE5"/>
    <dbReference type="FunCoup" id="A0A1C7NRE5">
        <property type="interactions" value="25"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NRE5"/>
    <dbReference type="InParanoid" id="A0A1C7NRE5"/>
    <dbReference type="OrthoDB" id="10250354at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051787">
        <property type="term" value="F:misfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051087">
        <property type="term" value="F:protein-folding chaperone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036503">
        <property type="term" value="P:ERAD pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018253">
        <property type="entry name" value="DnaJ_domain_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051948">
        <property type="entry name" value="Hsp70_co-chaperone_J-domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44360">
        <property type="entry name" value="DNAJ HOMOLOG SUBFAMILY B MEMBER 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44360:SF1">
        <property type="entry name" value="DNAJ HOMOLOG SUBFAMILY B MEMBER 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00625">
        <property type="entry name" value="JDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00636">
        <property type="entry name" value="DNAJ_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0143">Chaperone</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="129"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="domain" description="J" evidence="3">
        <location>
            <begin position="22"/>
            <end position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OBZ89824.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="202" mass="23343" checksum="C02A143C714A5640" modified="2016-11-30" version="1">MSFRNPCRHIRIRHYSTIRQKTPFEVLSLKQSATTAEIKSRYKELAKELHPDKKSTGDLAKFQELVQAYELLADPAKRSYYLRSGYGWTRDVNVSSPPPGQRPPSYTNAHWADEYPPVHGTRYTNNATFMSLLAGVVLMITTANIFYFQSSHGALLSAADRHHFKSSHDLKRAREEARLFGNDRGVKRVIESRMRLFREKEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NRR0</accession>
    <name>A0A1C7NRR0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Glycolipid 2-alpha-mannosyltransferase 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">MNT2_2</name>
        <name evidence="5" type="ORF">A0J61_00351</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the glycosyltransferase 15 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000007">
        <property type="protein sequence ID" value="OBZ91629.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NRR0"/>
    <dbReference type="STRING" id="101091.A0A1C7NRR0"/>
    <dbReference type="InParanoid" id="A0A1C7NRR0"/>
    <dbReference type="OrthoDB" id="439943at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000026">
        <property type="term" value="F:alpha-1,2-mannosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000032">
        <property type="term" value="P:cell wall mannoprotein biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006487">
        <property type="term" value="P:protein N-linked glycosylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.550.10:FF:000051">
        <property type="entry name" value="Alpha-1,2-mannosyltransferase (Ktr4)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="entry name" value="Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002685">
        <property type="entry name" value="Glyco_trans_15"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31121">
        <property type="entry name" value="ALPHA-1,2 MANNOSYLTRANSFERASE KTR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31121:SF6">
        <property type="entry name" value="ALPHA-1,2 MANNOSYLTRANSFERASE KTR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01793">
        <property type="entry name" value="Glyco_transf_15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0808">Transferase</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="30"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="10"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OBZ91629.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="460" mass="54450" checksum="B35C154547E5957F" modified="2016-11-30" version="1">MVFLRDNPFSSSDTNSPSKSSYNRRRTWKILFRISVATVVLTTCYFIGRGVHWEKISESYNPRDIDFSQYICNLPQTTLSKLLSSSSLAAIQQQQLSNANLLEHQRIEYLKTKETLVPDVTIPKDVWNGLPVKGAYYMVVRNEKIMDARMVARSMEDHMKNGTQYPWVLLNNQPFAVEFKRHIKKVITAPVFFGKIDLEAWDYPHWIDVDRAEFLMLEQETKGAYKGSSLSYHQLMRYHSGFFFHHPLLRDVEYTWRVEPGADYSCQMDDDMFLYMKEHNKSLGFVITMLEARQTIPTLWQRVNEFTERFPQHVLPEYETIYPWIYDEDADDYNNCHFWTNFQLADLSFFRSEAYRKYFEYLDRTGNFFYERWGDAPVQTIAAALFLKKEQIHFFNNIGYTHSVATHCPYNNTLLKKCHCDVNKNFDFHRSSCTKKLLKLLDPKAISSMNKFIKEKEIKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NS16</accession>
    <name>A0A1C7NS16_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 9">Cysteine dioxygenase</fullName>
            <ecNumber evidence="2 9">1.13.11.20</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">CDO1</name>
        <name evidence="10" type="ORF">A0J61_00029</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>L-cysteine + O2 = 3-sulfino-L-alanine + H(+)</text>
            <dbReference type="Rhea" id="RHEA:20441"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:35235"/>
            <dbReference type="ChEBI" id="CHEBI:61085"/>
            <dbReference type="EC" id="1.13.11.20"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="9">
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </cofactor>
        <text evidence="9">Binds 1 Fe cation per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 9">Belongs to the cysteine dioxygenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.13.11.20" evidence="2 9"/>
    <dbReference type="EMBL" id="LUGH01000001">
        <property type="protein sequence ID" value="OBZ91912.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NS16"/>
    <dbReference type="STRING" id="101091.A0A1C7NS16"/>
    <dbReference type="InParanoid" id="A0A1C7NS16"/>
    <dbReference type="OrthoDB" id="543511at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017172">
        <property type="term" value="F:cysteine dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008198">
        <property type="term" value="F:ferrous iron binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019448">
        <property type="term" value="P:L-cysteine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd10548">
        <property type="entry name" value="cupin_CDO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="entry name" value="Jelly Rolls"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010300">
        <property type="entry name" value="CDO_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12918">
        <property type="entry name" value="CYSTEINE DIOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12918:SF1">
        <property type="entry name" value="CYSTEINE DIOXYGENASE TYPE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05995">
        <property type="entry name" value="CDO_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="RmlC-like cupins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 9 10" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="6 8 9" id="KW-0408">Iron</keyword>
    <keyword evidence="3 8 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0883">Thioether bond</keyword>
    <feature type="binding site" evidence="8">
        <location>
            <position position="108"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="110"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="205"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="cross-link" description="3'-(S-cysteinyl)-tyrosine (Cys-Tyr)" evidence="7">
        <location>
            <begin position="115"/>
            <end position="222"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006622"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR610300-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR610300-51"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU366010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OBZ91912.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="255" mass="28221" checksum="EA2A85AAECF2CE84" modified="2016-11-30" version="1">MAPPQEPITLPEVYSMESTEMESKQMTLTDLVQSIHRVLGDEGLDSDKIDAKQIIALMEQYSSNAVDWNKYTLFDHSRAYTRNLIDDGNGKFNLMILAWSKGQKSPIHDHAGSHCVMKILDGELQETLFDWPATSADCNQLSSMQHDTEQIDITANRNASSGTGSVAAHIPCSESSLNGQPLVVAKDTVYHPNQVTYVHDKIGLHRISNPSNEQGAVSLHLYTPPYKMCKTFEEKTGKARSSGVCSFYSIGGNRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MTV2</accession>
    <name>A0A1C7MTV2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">CENP-V/GFA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">A0J61_11680</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the Gfa family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01002337">
        <property type="protein sequence ID" value="OBZ80270.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MTV2"/>
    <dbReference type="STRING" id="101091.A0A1C7MTV2"/>
    <dbReference type="InParanoid" id="A0A1C7MTV2"/>
    <dbReference type="OrthoDB" id="2212170at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016846">
        <property type="term" value="F:carbon-sulfur lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1590.10">
        <property type="entry name" value="glutathione-dependent formaldehyde- activating enzyme (gfa)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006913">
        <property type="entry name" value="CENP-V/GFA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011057">
        <property type="entry name" value="Mss4-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33337:SF31">
        <property type="entry name" value="DUF636 DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_2G12650)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33337">
        <property type="entry name" value="GFA DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04828">
        <property type="entry name" value="GFA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51316">
        <property type="entry name" value="Mss4-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51891">
        <property type="entry name" value="CENP_V_GFA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0456">Lyase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="CENP-V/GFA" evidence="5">
        <location>
            <begin position="5"/>
            <end position="118"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005495"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51891"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OBZ80270.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="154" mass="16772" checksum="45D9601587407FD6" modified="2016-11-30" version="1">MSTIYHGSCICGAIQFNLTGPPIRNIICHCSDCQKSGGSAFQTSSAYAPSQVQLIDPDNQLKTYIVPAESVGSGFEKHKHFCGRCGCPIYNVPMKEEGKQWIIKTGLIETSEGGSALHALKELQPQAEVYTRSRAGYLTAINNVNQFETGFQPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MUI1</accession>
    <name>A0A1C7MUI1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">ISXO2-like transposase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_11447</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01002041">
        <property type="protein sequence ID" value="OBZ80503.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MUI1"/>
    <dbReference type="STRING" id="101091.A0A1C7MUI1"/>
    <dbReference type="InParanoid" id="A0A1C7MUI1"/>
    <dbReference type="OrthoDB" id="2278611at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053164">
        <property type="entry name" value="IS1016-like_transposase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024445">
        <property type="entry name" value="Tnp_ISXO2-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47163">
        <property type="entry name" value="DDE_TNP_IS1595 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47163:SF2">
        <property type="entry name" value="SI:DKEY-17M8.2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12762">
        <property type="entry name" value="DDE_Tnp_IS1595"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01126">
        <property type="entry name" value="DDE_Tnp_IS1595"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ISXO2-like transposase" evidence="1">
        <location>
            <begin position="12"/>
            <end position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM01126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ80503.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="135" mass="15191" checksum="B130D06ED057C844" modified="2016-11-30" version="1">MIQEDLSSSDCRIGGCDENGNSIIVEIDESKFVPDRSARTLLSIKEEFVLPGSTVHTDYWAGYNSIENMGRELAHQTVNHSVEYVTVDGVHTNSIEGTWNGIKLNVVPRLRSRKMMPWVLVEVIWRCKHCGDITG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MUW0</accession>
    <name>A0A1C7MUW0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">F-box/WD repeat-containing protein 11</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">Fbxw11</name>
        <name evidence="5" type="ORF">A0J61_11329</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001912">
        <property type="protein sequence ID" value="OBZ80622.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MUW0"/>
    <dbReference type="STRING" id="101091.A0A1C7MUW0"/>
    <dbReference type="InParanoid" id="A0A1C7MUW0"/>
    <dbReference type="OrthoDB" id="19711at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053299">
        <property type="entry name" value="ASTRA_WD_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44156">
        <property type="entry name" value="SUPERNUMERARY LIMBS, ISOFORM B-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12937">
        <property type="entry name" value="F-box-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="F-box" evidence="4">
        <location>
            <begin position="38"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="127"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="166"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="206"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="246"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="286"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="329"/>
            <end position="368"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OBZ80622.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="413" mass="47544" checksum="4D7A1179B40DA0B2" modified="2016-11-30" version="1">MKSFTDKKLKLFKCFRKSETRIDEGFQQKSSITLLPKIDYLSALPIEIVWLILSFCDKDTILKCSSVSLYWHSLSQDNQLWRQLYLDHYGKPIYPIQGIHYRDLYQKKTQLAERWYSTDIYAQMQTILGHTDSIYCLQFDTTKMITGSRDRTIKIWNAHGQCLHTLVGHRASVLCLQYDQDMLVTGSSDHTLLVWSMETLEILFCLRAHTSGVLDVCFDQQSIVSCSKDATICIWNRQTGRLERTLRGHRGPVNAVQFHDRRLVSASGDTIIKLWDMETGQCLRDFVGHAHGLACVQFDGKKIVSGSNDNKIKVWNAGRADTGECLLTCVGHTALVRSLHFDKTKIVSGSYDQSIRVWDIQTGECIKTFSRCHTSWVFDVMFDETRIISASQDHKILIIDFAYDMHDIKQFLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MV34</accession>
    <name>A0A1C7MV34_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Endonuclease/exonuclease/phosphatase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_11220</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001792">
        <property type="protein sequence ID" value="OBZ80731.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MV34"/>
    <dbReference type="InParanoid" id="A0A1C7MV34"/>
    <dbReference type="OrthoDB" id="2290280at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="213"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ80731.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="213" mass="24325" checksum="AE5764C1A2D8D5CC" modified="2016-11-30" version="1" fragment="single">GQLSAPTFENHIDMLSTFKPSSQQVDYLPLEWTDHRLLSLHFRLFTKSDDNFSATANGRGFWKAHPCIAQDSEFQAILNFHLSATIRKLDSTLPAWHKWERIKLVAAKTARACSRRQGFSLARAESLLQRKRAKIESNLMNNPSLHPCLSPQLHIVQEQLTSLQQYHVETLSLKAGIRWREQGKLSAGYLKRTASARLTKTTVPPLFHPTLDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MV94</accession>
    <name>A0A1C7MV94_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">erg26_0</name>
        <name evidence="1" type="ORF">A0J61_11137</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001706">
        <property type="protein sequence ID" value="OBZ80815.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MV94"/>
    <dbReference type="STRING" id="101091.A0A1C7MV94"/>
    <dbReference type="InParanoid" id="A0A1C7MV94"/>
    <dbReference type="OrthoDB" id="10058185at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ80815.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="119" mass="13471" checksum="C97E5EF461C507C8" modified="2016-11-30" version="1" fragment="single">GAAGQAFNLTNGTPVPFWDFASRIWAVYGAYMPNNKKIVLSYNASMFIALISESILSIKQLFWDKSQLKEGMTRARIKQAMSSRYFNITKARTILGYEPQIGLDEGIQLSIAYYKAHHE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MVD0</accession>
    <name>A0A1C7MVD0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Acidic endochitinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">CHIA_1</name>
        <name evidence="4" type="ORF">A0J61_11120</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001691">
        <property type="protein sequence ID" value="OBZ80831.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MVD0"/>
    <dbReference type="InParanoid" id="A0A1C7MVD0"/>
    <dbReference type="OrthoDB" id="6020543at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004568">
        <property type="term" value="F:chitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001223">
        <property type="entry name" value="Glyco_hydro18_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050542">
        <property type="entry name" value="Glycosyl_Hydrlase18_Chitinase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45708">
        <property type="entry name" value="ENDOCHITINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45708:SF49">
        <property type="entry name" value="ENDOCHITINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00704">
        <property type="entry name" value="Glyco_hydro_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51910">
        <property type="entry name" value="GH18_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GH18" evidence="3">
        <location>
            <begin position="12"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="284"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OBZ80831.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="284" mass="32422" checksum="D28EBECBEE7C6344" modified="2016-11-30" version="1" fragment="single">MHQRRQILRRKDGLALYWGQGDYNEKRLSYYCDQEGVSIVILSFIANFSGGPKKSPVLDLSDNCKNTNNCSEAARDIKHCQKKGIKVLISLGGAVGPYKRQSWDPDLLAWWLWTKFLGGDDESVSRPFGDVVLDGVDYDPEGVDGEGYDRNIDTLRKLFKTQYPRREYLITAAPQCPDLEKYEKNAVYNILNPSNPKYNSYPNITFVQFYNNKCSASAYNSNKPTAFNFSAWNKWAQKTGSKIYLGVLGKQNNMDTGYVNYEKLTVILDDVERSKNFGGVMMWD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MVV5</accession>
    <name>A0A1C7MVV5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_11044</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001618">
        <property type="protein sequence ID" value="OBZ80907.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MVV5"/>
    <dbReference type="STRING" id="101091.A0A1C7MVV5"/>
    <dbReference type="InParanoid" id="A0A1C7MVV5"/>
    <dbReference type="OrthoDB" id="2212125at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ80907.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="125" mass="14107" checksum="CAD909268E8A30B5" modified="2016-11-30" version="1">MPRCKALKHRECKVAVKFTLIYDEVNDLTSYVVKCEGRHSHEKYKRLHLWGEKDKVLHEKVQNDHFIVSKSFSIGVTSLPGQFTSMAKGISSALGNQDRAKYQLSATKASLGISKSTGIWVILTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MWU0</accession>
    <name>A0A1C7MWU0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_10678</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001309">
        <property type="protein sequence ID" value="OBZ81273.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MWU0"/>
    <dbReference type="InParanoid" id="A0A1C7MWU0"/>
    <dbReference type="OrthoDB" id="2290051at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ81273.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="445" mass="51969" checksum="BFA74B6CD8FEE672" modified="2016-11-30" version="1">MSDFESKIKNFITTTRSPYLILFIIDYKNDIENSIESDSLDGFKLELSDAYVAAYQAVKNQKPEKRLYDVQWCVWEKLFAAAERRKKFDCTVSSKEGSSEIVGVKRLLDEMSITDWKIPNPAEEGLMIGDENNFSKIFFDYQVECLSKFKLEQFYNWRTDLQNLLALSSIVFLDGIRGACSFLDSNMYQVLYRLIRCDTGNTVALSSDAIEDLQGVLREYNEEYDYWATIGKIIHVHDKYKDNNLVNYNLEVLLSLLPEMTVFERKRSEMHVQCSYVHNFIKSIFKVDPWHHPHCSNTNNNFYSTRPDYLVDIQGSDTTMNNVFGECKAKHALIDSCNRDKYRLALFSQVAMQQQKLKSVMSFFSVDNEVTFYMMKKMNGMYFFIQIAKITIPTIESKFQDLGMHLNKIAMIRELYLSHCHEKEQEVGEFVSLPWIVLSEMTVKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-06-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MX03</accession>
    <name>A0A1C7MX03_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_10621</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001273">
        <property type="protein sequence ID" value="OBZ81330.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="InParanoid" id="A0A1C7MX03"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="40"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ81330.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="141" mass="15908" checksum="9D839ACF5CACAF83" modified="2016-11-30" version="1" fragment="single">MFHFIGTNNTNNVSSNNXIPSVRTTTXLPTAXSSVSDRRITNLEAAVTQLTREREEDRAXILALKRKNXELDAKLKKXRENSKLFGXPGSETELESLRQIIKRIEKKHVGADGWDLSETLMRGPTNSKKVKAIIDDFYVDT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MYB8</accession>
    <name>A0A1C7MYB8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Coiled-coil domain-containing protein 47</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">ccdc47</name>
        <name evidence="6" type="ORF">A0J61_10114</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001040">
        <property type="protein sequence ID" value="OBZ81837.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MYB8"/>
    <dbReference type="FunCoup" id="A0A1C7MYB8">
        <property type="interactions" value="301"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7MYB8"/>
    <dbReference type="InParanoid" id="A0A1C7MYB8"/>
    <dbReference type="OrthoDB" id="10039147at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032469">
        <property type="term" value="P:endoplasmic reticulum calcium ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012879">
        <property type="entry name" value="CCDC47"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12883">
        <property type="entry name" value="ADIPOCYTE-SPECIFIC PROTEIN 4-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12883:SF0">
        <property type="entry name" value="PAT COMPLEX SUBUNIT CCDC47"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07946">
        <property type="entry name" value="CCDC47"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008889363" evidence="5">
        <location>
            <begin position="21"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="347"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OBZ81837.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="347" mass="39691" checksum="1CB3CA533B718E68" modified="2016-11-30" version="1" fragment="single">MSAFLTSLAFVASTAAVAFAQEAEKKQPLEVSADNVMVRPFELRDFQMELVMAFAFVGYFLMWYRGKSANLNKAKQWLNGQIDYLESQFALVGDKKSTEKAVLMKDGPADYLLYTSGRRNVQFGHWWLKLKPRNDILSLFTTNLLSLTGYTKPASDRVELTLQLSSSLPEKFVFAVIKKDLASELAKNRFDLRRTCKIASSDIIPASLTIYSETQKLSDLILTKIGRVLRDNADKLEHLIISSLPAEEPEKYEQDKHMTLSFSFLMHDQESLQPFVQLACEIPDILSDMRFSNDVKSKISKNREELAKEHAKRIAADRAEELYQKKMEAKRAEEERIKKLSPAEQRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MYD8</accession>
    <name>A0A1C7MYD8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">CCHC-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">A0J61_10149</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001052">
        <property type="protein sequence ID" value="OBZ81801.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MYD8"/>
    <dbReference type="STRING" id="101091.A0A1C7MYD8"/>
    <dbReference type="InParanoid" id="A0A1C7MYD8"/>
    <dbReference type="OrthoDB" id="2202398at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.60.10">
        <property type="entry name" value="Zinc finger, CCHC-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001878">
        <property type="entry name" value="Znf_CCHC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036875">
        <property type="entry name" value="Znf_CCHC_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00098">
        <property type="entry name" value="zf-CCHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00343">
        <property type="entry name" value="ZnF_C2HC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57756">
        <property type="entry name" value="Retrovirus zinc finger-like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50158">
        <property type="entry name" value="ZF_CCHC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="CCHC-type" evidence="3">
        <location>
            <begin position="280"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="domain" description="CCHC-type" evidence="3">
        <location>
            <begin position="301"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="430"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="33"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OBZ81801.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="478" mass="52777" checksum="AA6D2DEB2CC0E91A" modified="2016-11-30" version="1">MVPPLQNTFGPLPTDSPISSQNASFEPLPDTQSSPSSPQPSLSPSLPPSLSSASSSSSSSSKPRMMSYAAATASSRTRNETVIYRSSTLSGQYNDTIHPVVHKTGTTDFSVFYHVPKKLAHLRSEVALRLSEKFPFGVGLGLTSTEDPLGTVIEISLVSQEACDNAVSQPVVVDEKKFHASPAIHPDRALLEVNLTKLPIWEGQRLRDSLLNNLSRYGVVREMTLYLDNWSGCWFTGNGHVYLERPNTNNKAYETLSYKIPLEGDNTFCLGTWTNMGKHCVYCKETGHYRKECTKAPTEKRRCYQCGNTGHIARNCFRTDTVDNTSNKRRRNERIEPKHRIMKTSQPVAEVAVQKGTNVTSPVVTSPETSAIVLEDVPPAESDTVIPSVPVRNLEPNSSPNVTCSTRNTSRRPAHLEDFVVPSSQEKTCKCGSASHRKTDYSQCPLNKKNLKDRSAMEISENEDQVAKNGLEQPSLPH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MYR2</accession>
    <name>A0A1C7MYR2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Protein Zds1 C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_09983</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000993">
        <property type="protein sequence ID" value="OBZ81967.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MYR2"/>
    <dbReference type="STRING" id="101091.A0A1C7MYR2"/>
    <dbReference type="InParanoid" id="A0A1C7MYR2"/>
    <dbReference type="OrthoDB" id="5589766at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030010">
        <property type="term" value="P:establishment of cell polarity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010971">
        <property type="term" value="P:positive regulation of G2/M transition of mitotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040206">
        <property type="entry name" value="Zds1/2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013941">
        <property type="entry name" value="ZDS1_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28089">
        <property type="entry name" value="PROTEIN ZDS1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28089:SF1">
        <property type="entry name" value="PROTEIN ZDS1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08632">
        <property type="entry name" value="Zds_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01327">
        <property type="entry name" value="Zds_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Protein Zds1 C-terminal" evidence="2">
        <location>
            <begin position="325"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="239"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="394"/>
            <end position="507"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="247"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="308"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="394"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="441"/>
            <end position="465"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM01327"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ81967.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="517" mass="59535" checksum="A82603FBA19CB514" modified="2016-11-30" version="1">MSTIYVYPLPSRTKPEPSILKSLDSTELSRILDIPLGLLETANNDDFFKNQFWLPPPSTATNTAIISADQIQDTEFDINTAQDYVNRKRSMVKRRKSVLSASFTASEEDIMRHKEEHKVEEEAVLEEEDEEDEEEMAIYHDKEQTNHFYSQENLTFNLQDDNNNNSVYYTNYDEITDTKNTLYPNEETYHITSILDTPKQEKPIANLQDSAIDLSIGSYPTTKDQADVVVELPPLDAPAKKTKKKVSSWSPRRIFSSSSNTPSTKKLNKKQSSSSLNSIESVESNESKERFHFSSLFSRKSGTKKSKQPSAQEKQPQSQPKQLSSSNTNLFNHTRLPINTERAIYRLSHIKLTNPRLPLRDQVVISNHMYWYLSIISANNESSTNVHQMIAMTKRHHRMQYQQKKGKKQNPRRPTNEQKTPQNKRMITAKRYPSAQLNSSSDDDDDSEDDLLDSDSDDDDDDENDAFNLKKPQLKNVPPLNNRNAKFKQTVKPRYSNHDEEEDDIPLAMYQKAKKAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-06-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MYS8</accession>
    <name>A0A1C7MYS8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_10391</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001150">
        <property type="protein sequence ID" value="OBZ81559.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MYS8"/>
    <dbReference type="InParanoid" id="A0A1C7MYS8"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ81559.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="150" mass="16868" checksum="ED5C8F2EB83EB0FF" modified="2016-11-30" version="1">MLSVIRDGFQITFASTSPTTATGKPVVFFDHKQEQLLSQVISSFLDKCAIELHLRHPEEDRRIMASLQPQGPEPVCSMSNIQDENNQRHISSYTTARLDDIYRPFGCFPSHISSSLLSTFSPFCMERGLLPVQNNSLCPLRGPLPVHKTH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MYW8</accession>
    <name>A0A1C7MYW8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_09924</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000973">
        <property type="protein sequence ID" value="OBZ82027.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MYW8"/>
    <dbReference type="InParanoid" id="A0A1C7MYW8"/>
    <dbReference type="OrthoDB" id="2284908at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ82027.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="148" mass="17089" checksum="602A749F95E78D4A" modified="2016-11-30" version="1">MNPSPKLSKYVFMPLALLQSELFWLYSVLYCMFRSGSDQPLAVKRPTVIKLNPQLDVLIEESDEETEDPSEPNDIVIGIRQRPTVIDELNGTTCPPIWWQKTRIRLGKPPVHSKRSSSDSSSDESACSYRRKNFFSKLALHHHSRRHH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MZF0</accession>
    <name>A0A1C7MZF0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Serine-threonine protein phosphatase N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">A0J61_09829</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000949">
        <property type="protein sequence ID" value="OBZ82118.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MZF0"/>
    <dbReference type="STRING" id="101091.A0A1C7MZF0"/>
    <dbReference type="InParanoid" id="A0A1C7MZF0"/>
    <dbReference type="OrthoDB" id="10448337at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031675">
        <property type="entry name" value="STPPase_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16891">
        <property type="entry name" value="STPPase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0464">Manganese</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Serine-threonine protein phosphatase N-terminal" evidence="5">
        <location>
            <begin position="146"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="52"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="52"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="188"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF16891"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OBZ82118.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="188" mass="21128" checksum="41ED17191912811B" modified="2016-11-30" version="1" fragment="single">MGNSISKRKKERLQKHKRQKEPPRVDITPADNEYSINTAQSVNSILMTSSQHHSALSQLNPDYPVGQQNSQEEEDSLQQGDAFMGKVEHPQQHKLLAQSDFWPPKRASGQSIEIEIDNNQLTVSSMNQLTMHSISSLNLQNSIANIDDYIRRLLDAGYATKVPKQLCLKASEVTAICRVAMDIFLSQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MZU0</accession>
    <name>A0A1C7MZU0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Transcription initiation factor IIB</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">General transcription factor TFIIB</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="primary">sua7_0</name>
        <name evidence="12" type="ORF">A0J61_09669</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">General factor that plays a major role in the activation of eukaryotic genes transcribed by RNA polymerase II.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Associates with TFIID-IIA (DA complex) to form TFIID-IIA-IIB (DAB-complex) which is then recognized by polymerase II.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the TFIIB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000905">
        <property type="protein sequence ID" value="OBZ82281.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MZU0"/>
    <dbReference type="FunCoup" id="A0A1C7MZU0">
        <property type="interactions" value="652"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7MZU0"/>
    <dbReference type="InParanoid" id="A0A1C7MZU0"/>
    <dbReference type="OrthoDB" id="25790at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097550">
        <property type="term" value="C:transcription preinitiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016251">
        <property type="term" value="F:RNA polymerase II general transcription initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017025">
        <property type="term" value="F:TBP-class protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051123">
        <property type="term" value="P:RNA polymerase II preinitiation complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd20551">
        <property type="entry name" value="CYCLIN_TFIIB_rpt1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.472.10:FF:000141">
        <property type="entry name" value="Transcription initiation factor IIB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.472.170:FF:000001">
        <property type="entry name" value="Transcription initiation factor IIB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.20.25.10:FF:000036">
        <property type="entry name" value="Transcription initiation factor IIB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.170">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.10">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013763">
        <property type="entry name" value="Cyclin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036915">
        <property type="entry name" value="Cyclin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000812">
        <property type="entry name" value="TFIIB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023486">
        <property type="entry name" value="TFIIB_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013150">
        <property type="entry name" value="TFIIB_cyclin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013137">
        <property type="entry name" value="Znf_TFIIB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11618:SF13">
        <property type="entry name" value="TRANSCRIPTION INITIATION FACTOR IIB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11618">
        <property type="entry name" value="TRANSCRIPTION INITIATION FACTOR IIB-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00382">
        <property type="entry name" value="TFIIB"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08271">
        <property type="entry name" value="Zn_Ribbon_TF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00685">
        <property type="entry name" value="TIFACTORIIB"/>
    </dbReference>
    <dbReference type="SMART" id="SM00385">
        <property type="entry name" value="CYCLIN"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47954">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57783">
        <property type="entry name" value="Zinc beta-ribbon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00782">
        <property type="entry name" value="TFIIB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51134">
        <property type="entry name" value="ZF_TFIIB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="4" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="9" id="KW-0862">Zinc</keyword>
    <keyword evidence="9" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="TFIIB-type" evidence="11">
        <location>
            <begin position="29"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00031706"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00056616"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00066213"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00469"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="OBZ82281.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="340" mass="37310" checksum="9E34D7E52D4CC7D2" modified="2016-11-30" version="1">MTTAIPFPLRDPQIKDDGKPKQFIPNLNVKLVCPDCRVDPPQIVEEFASGDLVCGDCGLVLGDRIIDTRSEWRTFANDEGDDPSRVGAAANPLLDGNQLDTVISRRDGGSGAAKDLNKVHGRATAVKGERNLVQAYKEISAMCDSISLSKIVSDTAKQLYKRVEDEKLLRGKSSDAIIAACIFIACRQEKVGRTFREICALTRVPKKEIGRCYKSLQSKLQTNTSIMNSEDLMLRFCSNLQLPNYVQKAGIDLVKRAKEHGTLAGKSPISVAAACIYLVSYLYRQPKSTRDIAHVAGVSEVTIKSAYKSLYAEKDSLVDIDALRTKPNGENLSFEDLALP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MZU3</accession>
    <name>A0A1C7MZU3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">GTPase-activating protein gyp3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">gyp3_0</name>
        <name evidence="3" type="ORF">A0J61_09535</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000872">
        <property type="protein sequence ID" value="OBZ82415.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MZU3"/>
    <dbReference type="FunCoup" id="A0A1C7MZU3">
        <property type="interactions" value="97"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7MZU3"/>
    <dbReference type="InParanoid" id="A0A1C7MZU3"/>
    <dbReference type="OrthoDB" id="294251at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031267">
        <property type="term" value="F:small GTPase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.270:FF:000016">
        <property type="entry name" value="TBC1 domain family member 2A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.270">
        <property type="entry name" value="putative rabgap domain of human tbc1 domain family member 14 like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.750">
        <property type="entry name" value="Ypt/Rab-GAP domain of gyp1p, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.80">
        <property type="entry name" value="Ypt/Rab-GAP domain of gyp1p, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000195">
        <property type="entry name" value="Rab-GAP-TBC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035969">
        <property type="entry name" value="Rab-GAP_TBC_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050302">
        <property type="entry name" value="Rab_GAP_TBC_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47219">
        <property type="entry name" value="RAB GTPASE-ACTIVATING PROTEIN 1-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47219:SF20">
        <property type="entry name" value="TBC1 DOMAIN FAMILY MEMBER 2B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00566">
        <property type="entry name" value="RabGAP-TBC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00164">
        <property type="entry name" value="TBC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47923">
        <property type="entry name" value="Ypt/Rab-GAP domain of gyp1p"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50086">
        <property type="entry name" value="TBC_RABGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rab-GAP TBC" evidence="2">
        <location>
            <begin position="274"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="74"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="112"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="125"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="185"/>
            <end position="194"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ82415.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="613" mass="71167" checksum="6123B754153963EB" modified="2016-11-30" version="1">MDEANYRRFSGRVRSSSFNHSFTRRQQPEVVTRRRPSFDSHNRQQRIREQQLQEQQKQQQQQQYYASTNNYLNVAKPRYPTGGTSSFDESGSELEDDEISIYQSYMYTPSASTTQLDNQKPFVDSPNSIAEDQSGNKSLSHSFKERLSVSRMSLRKGASPSSSSMGGHKFGNILGSKSSSSSSSTTNNPEQPQQLYDDGSNAIYPPPQKQTGERDQYGFLKSSQWVTADAYAQFEQRYTPIVKRRLQKWRQLLYENNDQWPSRSSKVKRYIRKGIPPELRGQAWLHYSGAKTEMEANGGLYYELVDRAEQMGNANENMEIIDRDLHRTFPENNRFRPESMINNNNTTAEEKMNIPIIKSLRRVLLAFSLYSPSIGYCQSLNYIAGMLLLFMTEEEAFWTFVVLVTKILPPNIYDVTMEGANIDQNVLMILISERLPHLWNRLSGGKSFWDCEEQESVGMPTCSLVTSHWFLTLFINILPVETVLRVWDCLFYDGQKVLFRVALGIFKLNENEILQVQDPLEVFQVIQNMPKRMVDCNKLIDGTYMQYAATTRVTDEEIVDRRELFKKRRDERRRNIPVQKGHKLLKRSTMRGAIIHKAKEARYYVERAKTVRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MZX7</accession>
    <name>A0A1C7MZX7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 10">Catalase</fullName>
            <ecNumber evidence="3 10">1.11.1.6</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="primary">katE_0</name>
        <name evidence="16" type="ORF">A0J61_09575</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>2 H2O2 = O2 + 2 H2O</text>
            <dbReference type="Rhea" id="RHEA:20309"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16240"/>
            <dbReference type="EC" id="1.11.1.6"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 10 12">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the catalase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.11.1.6" evidence="3 10"/>
    <dbReference type="EMBL" id="LUGH01000882">
        <property type="protein sequence ID" value="OBZ82373.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MZX7"/>
    <dbReference type="STRING" id="101091.A0A1C7MZX7"/>
    <dbReference type="InParanoid" id="A0A1C7MZX7"/>
    <dbReference type="OrthoDB" id="6880011at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004096">
        <property type="term" value="F:catalase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042744">
        <property type="term" value="P:hydrogen peroxide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006979">
        <property type="term" value="P:response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03132">
        <property type="entry name" value="GATase1_catalase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.180.10:FF:000003">
        <property type="entry name" value="Catalase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1370.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.180.10">
        <property type="entry name" value="Catalase core domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018028">
        <property type="entry name" value="Catalase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024712">
        <property type="entry name" value="Catalase_clade2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043156">
        <property type="entry name" value="Catalase_clade2_helical"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011614">
        <property type="entry name" value="Catalase_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002226">
        <property type="entry name" value="Catalase_haem_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010582">
        <property type="entry name" value="Catalase_immune_responsive"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041399">
        <property type="entry name" value="Catalase_large_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020835">
        <property type="entry name" value="Catalase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42821">
        <property type="entry name" value="CATALASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42821:SF1">
        <property type="entry name" value="CATALASE-B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00199">
        <property type="entry name" value="Catalase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06628">
        <property type="entry name" value="Catalase-rel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18011">
        <property type="entry name" value="Catalase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF038927">
        <property type="entry name" value="Catalase_clade2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00067">
        <property type="entry name" value="CATALASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM01060">
        <property type="entry name" value="Catalase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="Class I glutamine amidotransferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56634">
        <property type="entry name" value="Heme-dependent catalase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00437">
        <property type="entry name" value="CATALASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51402">
        <property type="entry name" value="CATALASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 10" id="KW-0349">Heme</keyword>
    <keyword evidence="9 10" id="KW-0376">Hydrogen peroxide</keyword>
    <keyword evidence="8 10 12" id="KW-0408">Iron</keyword>
    <keyword evidence="6 10 12" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 10" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4 10" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="14" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="14">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008889380" description="Catalase" evidence="14">
        <location>
            <begin position="22"/>
            <end position="784"/>
        </location>
    </feature>
    <feature type="domain" description="Catalase core" evidence="15">
        <location>
            <begin position="56"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="active site" evidence="11">
        <location>
            <position position="102"/>
        </location>
    </feature>
    <feature type="active site" evidence="11">
        <location>
            <position position="175"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="12">
        <location>
            <position position="389"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <feature type="cross-link" description="3'-histidyl-3-tyrosine (His-Tyr)" evidence="13">
        <location>
            <begin position="366"/>
            <end position="389"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012314"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRNR" id="PIRNR038927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR038927-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR038927-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR038927-4"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="SMART" id="SM01060"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="OBZ82373.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="784" mass="87750" checksum="0B86F1F08867BCEA" modified="2016-11-30" version="1">MKINVLTSCVSLFMAAQLVAGDGSCALTGSNEKNPLNAKQEQLNKFTINDAGTQETTTFGLKVNNSDSLKAGLEGPTLLEDFMLREKTTHFDHERIPERVVHARGVGVHGYFESYDDYSDITAASFLNKKGKQTPVFVRFSTVLGSRGSSDTVRDVRGFAVRFYTDEGNFDLVGNDIPSFFVNDGIKFLDLIHAAKPQPDTEVPQAQTAHETAYDFFAEFPESIHTVLWVLSGRGIPRSLRQIEGFGVNTMRFINEKGESHFVKFMWKPKQGLANLAWDEAQKIAGNDPDFHRNDLYKAIQNGDYPEWEWGVQLVKESEAEKFNFSILDATKIIPESLVPFKPMGRLVLNRNPDNFFAETEQVTFHLGHIVRGIGFSNDPLLHSRLFSYIDTQINRMNSVNYMQLPINRPIVPVHNNQRDGFMQSQIHKGKVAYSPNRLQQDTPSLVPPEEGGWIDYPEKMKDATKLRGRPASFFDYYSQATLYYNSLTEPEKQNLVDAARFEIGKSKDQGVRERMVNVLNNVDNNLARRVALGLGITLPEKIKDNHNQTSIGLSIEKRPKPDNIKTRTVAILTAPGTNTKEAKAMYNFLQSKGAYPEYIGIHLGSQYGLNVTNTYLTASSVLYDAVYVPGGNVSITTMTSKTSFFPVDEPKVFIMDAFRHAKPIAASSEGIKLLEYAGIELPEGTSGLREKDGVILGDNESSLQRSFEKALKQQRFWSRLPIDPHAVYNPLSAVEQVASAGQDMLSHSLKKVSTIQQAASYLVKNRFQNAFGVIQEAVQAIRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N038</accession>
    <name>A0A1C7N038_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Thc1 RRM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_09469</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000857">
        <property type="protein sequence ID" value="OBZ82480.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N038"/>
    <dbReference type="InParanoid" id="A0A1C7N038"/>
    <dbReference type="OrthoDB" id="5418203at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039884">
        <property type="entry name" value="R3HC1/R3HCL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053800">
        <property type="entry name" value="Thc1_RRM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21678:SF0">
        <property type="entry name" value="C3H1-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21678">
        <property type="entry name" value="GROWTH INHIBITION AND DIFFERENTIATION RELATED PROTEIN 88"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22877">
        <property type="entry name" value="RRM_Thc1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thc1 RRM" evidence="2">
        <location>
            <begin position="168"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="89"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="285"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="32"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="59"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="111"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="285"/>
            <end position="301"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF22877"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ82480.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="307" mass="35538" checksum="8AAE7B06258E6007" modified="2016-11-30" version="1">MSSMEGESKSRRPVMQPYVPVHRRNQQQSVPSISSTRHSASSIKDENDVKRRGRGQFRAPSNDSFTSLSATEEQLDLTSLKQEMPLVCSEKKTQQVETQANENKEEKKEKEEEEEEEEEWESALNLNIKTKLAVKPITATATTILYQNYECAYRHKLDDEATTVLDCYDFPNTFKTFHLKDIFKEYDSMRGGYEIKWMDDTRALIVFEHPHTAKKAYIENLHSPLFKIKPYRGHIERKPTGPVPRRPVTTDMVAKRLVHNALGVRSTKTPEQRQAEKDLLRATREQRHAEKAKLANREKALSDAFNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N080</accession>
    <name>A0A1C7N080_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">ABC1 family protein MCP2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">MCP2</name>
        <name evidence="4" type="ORF">A0J61_09519</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein kinase superfamily. ADCK protein kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000868">
        <property type="protein sequence ID" value="OBZ82431.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N080"/>
    <dbReference type="FunCoup" id="A0A1C7N080">
        <property type="interactions" value="209"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N080"/>
    <dbReference type="InParanoid" id="A0A1C7N080"/>
    <dbReference type="OrthoDB" id="427480at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055088">
        <property type="term" value="P:lipid homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007005">
        <property type="term" value="P:mitochondrion organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd13969">
        <property type="entry name" value="ADCK1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004147">
        <property type="entry name" value="ABC1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045307">
        <property type="entry name" value="ADCK1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051130">
        <property type="entry name" value="Mito_struct-func_regulator"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43173:SF19">
        <property type="entry name" value="AARF DOMAIN-CONTAINING PROTEIN KINASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43173">
        <property type="entry name" value="ABC1 FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03109">
        <property type="entry name" value="ABC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="38"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="domain" description="ABC1 atypical kinase-like" evidence="3">
        <location>
            <begin position="156"/>
            <end position="412"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF03109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OBZ82431.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="580" mass="66999" checksum="04D6BF8F5FF13B78" modified="2016-11-30" version="1">MNQSQLLTRHSIRLFSRPHLRHATSLTHPSRKSLPRRLVQGAAMATLATTLTVGIGSTVLYYTSDRFRHVAHALDRCRLAGTVGAQVAYDYHRTLAQTYPDPDGYDEAIRACHQRSANKVLRAIQQLGGVYVKLGQHISVMQYLLPDEWCLTMRVLQDQCVPTPPEAIEALFMSDMGLPVESIFEEFDWTPLGVASLAQVHRAKLAHQPDSEDDLWVAVKLQHPYLDEYCQLDMDTVSFLFEIIKRVFPDFGFDWFAEEMRESIPKELDFVHETQNARRVRDNFADDVDQHRTSLVIPKVIWAKRRIMCMEFINGSRVDDLEYMRQHQIDPREVSNELTRVFSEMIFLHGFVHCDPHPGNVFIRANKNAKHNFDLVLLDHGLYRELSDELRSNYAQLWTSLIKADEQGIQTYAQLVGGTEIYQLFACMLTGREWDKITQSDLGSTRQVEEVGRISEGALTYLVEVADILAKLPRPVLLLLKTNDLLRHVDEKLNANSDERMTYVLMGSYCSKAVWLDTKRYLSEKIRVVGFRWSLLKALVRAWWQYKSVTWLLWIYQISLKVTEKVNWSNPKKITHSSSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N096</accession>
    <name>A0A1C7N096_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Serine/threonine-protein kinase pkpA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">pkpA_1</name>
        <name evidence="4" type="ORF">A0J61_09531</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000871">
        <property type="protein sequence ID" value="OBZ82418.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N096"/>
    <dbReference type="STRING" id="101091.A0A1C7N096"/>
    <dbReference type="InParanoid" id="A0A1C7N096"/>
    <dbReference type="OrthoDB" id="4062651at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004672">
        <property type="term" value="F:protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd13983">
        <property type="entry name" value="STKc_WNK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:001565">
        <property type="entry name" value="WNK protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050588">
        <property type="entry name" value="WNK_Ser-Thr_kinase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13902">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE WNK WITH NO LYSINE -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="3">
        <location>
            <begin position="102"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="615"/>
            <end position="646"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="449"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="628"/>
            <end position="646"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OBZ82418.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="646" mass="73532" checksum="33266697BBE31FDA" modified="2016-11-30" version="1">MSSDNTIASHQSMQDNKNLRVSFTTDNEPDYTNYYAPLSQNYISNPTDMPSSVDYTSFQRTVSTIPNLDSPYGIPISNDINDQSRSHDSEKVVEVSPNERYVRLNTLLGKGAYKVVYKAIDREEGYEVAWNTMQAMQSPNNKDLEHEIQILKSVRHPNIIAFHDAWYGDNEFVFITELMTSGTLREYIRKLAPLPNLKIIKRWSRQILKGLAYLHGHNPPIIHRDIKCDNIFINGAHGEVKIGDMGTAEMKLGKKYTLIGTPEFMAPEMYEEQGYNEKVDIYAFGMCLLEMATGEYPYGECKNAAQIYKKVSSGIKPACLSRVQNPEVLRVIENCLSNEHERMSAQEILEHSFLAVEPDVVLLAADPDNIHLTLQVVFKGMDKLSVKFDFNVETDTAEEVVREMIEEQVLPERYQHHITKEINRILRDIEKPTESEQAEQVRRSVWRRESDIRNELDRTKEELNHATDRVLEVEQKCNDFESRAQAAESRYKNALRSLKELEELKYASSTEDTSMANLSLNNATDEREREKLVNHILDEYSDDTDISVFVADCAQASHRGADKAHEWARKLQNQDIMTVGDLRDLHDEDWAGIGLTVFALRALKNMLKGKNLAANSVLTPSSPPPTTPLSSSSLPPTYPSQPTSTM</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N0I6</accession>
    <name>A0A1C7N0I6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Endonuclease/exonuclease/phosphatase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_09801</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000940">
        <property type="protein sequence ID" value="OBZ82149.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N0I6"/>
    <dbReference type="InParanoid" id="A0A1C7N0I6"/>
    <dbReference type="OrthoDB" id="2443300at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.10.10">
        <property type="entry name" value="Endonuclease/exonuclease/phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036691">
        <property type="entry name" value="Endo/exonu/phosph_ase_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56219">
        <property type="entry name" value="DNase I-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="246"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ82149.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="246" mass="28209" checksum="FC2262F8BE8E37F4" modified="2016-11-30" version="1" fragment="single">MLHLSDDLLPDMDRVILSEVSSPNQLFLPFYVVVIYAPANSARERREFFSTLYTTLQSPTLALNFDRLLCMGDFNYSYLRPNLSTATSLEWVSSLDTYCFNALQAFDLHELPTFRRNDSITSTIDYIFASHSFRNVLVDANLHLINPSWTDHSLLSVRMALAAAPTGPGLWRANPRLLQNPAYQQRLIDVIPLLLAEATSKFVTPQDQWDFFKKALKRVTKCFGVNRAKDHKTRLRGLQSQRNHLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N0Q5</accession>
    <name>A0A1C7N0Q5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Formin-A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">forA</name>
        <name evidence="4" type="ORF">A0J61_09225</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000802">
        <property type="protein sequence ID" value="OBZ82725.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N0Q5"/>
    <dbReference type="STRING" id="101091.A0A1C7N0Q5"/>
    <dbReference type="InParanoid" id="A0A1C7N0Q5"/>
    <dbReference type="OrthoDB" id="2286011at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005884">
        <property type="term" value="C:actin filament"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008017">
        <property type="term" value="F:microtubule binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045010">
        <property type="term" value="P:actin nucleation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.630">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.30.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.2220">
        <property type="entry name" value="Formin, FH2 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014767">
        <property type="entry name" value="DAD_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015425">
        <property type="entry name" value="FH2_Formin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042201">
        <property type="entry name" value="FH2_Formin_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001265">
        <property type="entry name" value="Formin_Cappuccino_subfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051425">
        <property type="entry name" value="Formin_Homology"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45725:SF1">
        <property type="entry name" value="DISHEVELLED ASSOCIATED ACTIVATOR OF MORPHOGENESIS, ISOFORM D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45725">
        <property type="entry name" value="FORMIN HOMOLOGY 2 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02181">
        <property type="entry name" value="FH2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00828">
        <property type="entry name" value="FORMIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00498">
        <property type="entry name" value="FH2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101447">
        <property type="entry name" value="Formin homology 2 domain (FH2 domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51231">
        <property type="entry name" value="DAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51444">
        <property type="entry name" value="FH2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FH2" evidence="3">
        <location>
            <begin position="1"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="domain" description="DAD" evidence="2">
        <location>
            <begin position="420"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="394"/>
            <end position="519"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="394"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="423"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="448"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="468"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51231"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51444"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OBZ82725.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="519" mass="59674" checksum="F9AB12C76959B89E" modified="2016-11-30" version="1" fragment="single">PAVKTRQLQWQKLNAGKIGSTVWKLGTSNEKEEELEALLDKEGIFDRMEQVFAQKVVQSKRALPKERRQEINIIDSRKAYNISIAVLAKCKHVTFDEFKKKILAVDEKFCTEILLRNLLVNLPSHDEMGKLSVFIKTASEEDLASLAKPDAFCAEILSIDRVRERITNMLFVNTFNERITQLSKNMSNVMNASTQLKDSQSIRDLLNIILLVGNFLNGTNFQGGAFGVRISSINKLVDTRASSNDTTLLHFLCTLIEEKFPSINDHLLEDLELCGEACRVTIQDLIKDYNELRVGLQTLIHELDCHYSGDYVAEQGDNFAAVMYNFRDRAIERFDQLEVRYTSMDVAYKDVVSYFGEDASEMKPDEFFGIFQTFTSSWTKAKSDLVLLKRKEEQAEKTKQFQEQRKARLNKRLDMSETNSENQDDKDIMDNLLEKLRSGEMTTGSQQRKNRMSTRERRRTRAESMVVKAEDLLRHIQSEEEVPPLPRPARSASRRFTSSDRMKKLASLADRTETNPMQT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-06-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N0X3</accession>
    <name>A0A1C7N0X3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_09220</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000800">
        <property type="protein sequence ID" value="OBZ82733.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N0X3"/>
    <dbReference type="InParanoid" id="A0A1C7N0X3"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ82733.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="134" mass="15272" checksum="16D65D00FAA5353F" modified="2016-11-30" version="1">MAICKFRIGENTVILEAQEGYYFRLNASILKCLKALREEEVVVAFSLSRLFVPLDIRLINEEFSQPVAALYNLKAFSVQQAERPELTLSGIRSRYPQVPELNSYEIQSSPDRRNGFGPLDTVPQINVAPYFSKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N0Y3</accession>
    <name>A0A1C7N0Y3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein C2E12.03c</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">A0J61_09177</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000791">
        <property type="protein sequence ID" value="OBZ82770.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N0Y3"/>
    <dbReference type="InParanoid" id="A0A1C7N0Y3"/>
    <dbReference type="OrthoDB" id="407617at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.290">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006603">
        <property type="entry name" value="PQ-loop_rpt"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04193">
        <property type="entry name" value="PQ-loop"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00679">
        <property type="entry name" value="CTNS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="6"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="30"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="55"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OBZ82770.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="116" mass="13270" checksum="7290B284083CE3C0" modified="2016-11-30" version="1" fragment="single">QFFGVLPVVFVIVGFLPQYYEIFRERRVIGVSHVFLAMDFFGSVFSIVSLDVLALVNYIAIGCLDVGILTLYYIFEWYQSRKEKDTETAIREISDDCEDVQSTKFSPLEACTKTTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N124</accession>
    <name>A0A1C7N124_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="21">Dicer-like protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="21" type="primary">DCL1</name>
        <name evidence="21" type="ORF">A0J61_09218</name>
    </gene>
    <organism evidence="21 22">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="21 22" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="21 22">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="13 14">Belongs to the helicase family. Dicer subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="21">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000800">
        <property type="protein sequence ID" value="OBZ82731.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="FunCoup" id="A0A1C7N124">
        <property type="interactions" value="354"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N124"/>
    <dbReference type="InParanoid" id="A0A1C7N124"/>
    <dbReference type="OrthoDB" id="416741at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004525">
        <property type="term" value="F:ribonuclease III activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031047">
        <property type="term" value="P:regulatory ncRNA-mediated gene silencing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006396">
        <property type="term" value="P:RNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd18034">
        <property type="entry name" value="DEXHc_dicer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00593">
        <property type="entry name" value="RIBOc"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000628">
        <property type="entry name" value="Endoribonuclease Dicer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1520.10:FF:000004">
        <property type="entry name" value="Endoribonuclease dicer-like 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.380">
        <property type="entry name" value="Dicer dimerisation domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.260.10">
        <property type="entry name" value="paz domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1520.10">
        <property type="entry name" value="Ribonuclease III domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038248">
        <property type="entry name" value="Dicer_dimer_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005034">
        <property type="entry name" value="Dicer_dimerisation"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014720">
        <property type="entry name" value="dsRBD_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006935">
        <property type="entry name" value="Helicase/UvrB_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000999">
        <property type="entry name" value="RNase_III_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036389">
        <property type="entry name" value="RNase_III_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14950">
        <property type="entry name" value="DICER-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14950:SF37">
        <property type="entry name" value="ENDORIBONUCLEASE DICER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03368">
        <property type="entry name" value="Dicer_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04851">
        <property type="entry name" value="ResIII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00636">
        <property type="entry name" value="Ribonuclease_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00535">
        <property type="entry name" value="RIBOc"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69065">
        <property type="entry name" value="RNase III domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51327">
        <property type="entry name" value="DICER_DSRBF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50137">
        <property type="entry name" value="DS_RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00517">
        <property type="entry name" value="RNASE_3_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50142">
        <property type="entry name" value="RNASE_3_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="15" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-0347">Helicase</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-0460">Magnesium</keyword>
    <keyword evidence="12" id="KW-0464">Manganese</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="22" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="10 14" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="11" id="KW-0943">RNA-mediated gene silencing</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="18">
        <location>
            <begin position="48"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="19">
        <location>
            <begin position="403"/>
            <end position="562"/>
        </location>
    </feature>
    <feature type="domain" description="Dicer dsRNA-binding fold" evidence="20">
        <location>
            <begin position="604"/>
            <end position="714"/>
        </location>
    </feature>
    <feature type="domain" description="RNase III" evidence="17">
        <location>
            <begin position="1034"/>
            <end position="1165"/>
        </location>
    </feature>
    <feature type="domain" description="RNase III" evidence="17">
        <location>
            <begin position="1209"/>
            <end position="1357"/>
        </location>
    </feature>
    <feature type="domain" description="DRBM" evidence="16">
        <location>
            <begin position="1423"/>
            <end position="1455"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="15">
        <location>
            <begin position="1436"/>
            <end position="1463"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00035116"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00657"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS50142"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="PROSITE" id="PS51327"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="EMBL" id="OBZ82731.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="1478" mass="169728" checksum="2B3C952D24A67151" modified="2016-11-30" version="1">MTEIYLDPEFVDLTPEKATELNNTEKQKGQEEQTAAPILFPREYQYELLKKAISENVIAVLDTGAGKTLISVMLIKHMLAVEAQKAEADANYKRKIIFFIVDRVPLVFQQANVIKSNCDARLKEICGDMNVDTWAKKTWRDIFEHSDICVLTAEIFKSTLQRGFLSLEEVCLMIFDECHHAVKGHPFNMIMYEFYHRWEVDKSLKPKIFGMTASPIYSSKTEVMLNITKLETNLDCRVFTAKNTLELQQSVRKPFELIREYSMHPIDDLPPPDNKYQTPMPQKLKRVELRYPETPLTYAITNKIHRIAGFYQCQATADYISNNLGSWCSDRIWKVMLYGAHKYGLFTPTLYMPEQNLSQKEIMLMQEAYKLCPEEIPPPDIKDGTLFTPKAQALIDCLSHILDTDDKSEEFCGIIFVERRHTAVAIKILIEQIEELNMMFRCEVLYGHGTATGGNLQMKYTVQNEVIAKFRKGKINLMIATNVAEEGLDIQACNYVIRFDITKTAIGYIQSRGRARKAGSKYIVILNTDSEKEAKLIEQLKLAEVQMKEFCHKLPEDRNILIEHAATNDQRYNTEYIRTNTSASYLAGAYEIISTGALLTLSSSVSLVHHYCATLPADDFCNFQPIYEIWKIETKDQLNKLDIYIKEEFNILLQENWFGKVTIPINQELVSFECISNNIDKAKAKASLKACIALHQAQLIDDHLVPTIYAQKMKLKEEKELDSDGREVGSRRRENYYPMISPSLWSEDEKEELERKEKKGPYYISLLDISNSFNKFRPMCLVTKKPLPFIPNITLYNNDQALEVSFKSNSISFQFFNEYYTNLFHEYTLACLRWINNKTFTCPNGDLPYYLAPVIRKIEKEALNANFELYIDMNEIRTTIKNDSKQYLDLDSLPDYQDVIIKDTSDQCRRSYFIESIEKTMTPLSKPPRLANVSISNKRYTHQQQLREADFDTFLEYYKELEELKISISDLEQPLIQVSRLAKNETYSFNPAHKDKNKKDNPSDRVVLWLVPELCQLLPISLSVYRTLHVIPYIMDFVDHFLLAYDAKKAIDLPKINDVLMFEAYKASSADTINNYQRLEFLGDSVLKFITSNHVYIKFPAGKEFELTENRGSQRTSQRLWRPPGLVSDADSPEMKKQLEQQKLSDKTLADVIESTLGASFLSQGLDGSIYAAHQLLVPLEDIRRWSDFNAAYRKLHSNYDPTLLEVNVERVSHILGYTFADPSLLVEALTHASMIGSSVPSYQRLEFLGDAVLDFCVTKYLYDKYNTSPPGVLHNLRKSSVNNDILSVLCVQLKLHHHVRHLSDRLINATKDFEQMLDAAKEEGSDHDEYWLDGNAPKVLADVVESIIGAIYVDSGFKLDPIYLFFEATLKPLLDKHISIQSSEAHPLTQFVHLIQGLGCIDYDIVNIVQKQVGPNTQKCVIFIHSTAFSSGSGYNVNEARKQAAQXAIDRLKNDASFLSTTCCCQEEECRLNQETQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N149</accession>
    <name>A0A1C7N149_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_09131</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000781">
        <property type="protein sequence ID" value="OBZ82817.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N149"/>
    <dbReference type="InParanoid" id="A0A1C7N149"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="61"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="65"/>
            <end position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ82817.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="401" mass="45936" checksum="D7FB152D4BA71E13" modified="2016-11-30" version="1">MSQDTANEISILIDEYFAKTKNPNLVHFKNTNSQHMEAMSDSEQRKIIVLFKSKEAEHVKKDFVNSPDSSSNNNNNSSSNNDDDDASPSSSLSPLNHDLNIQVSSLATTVTASETPLGVKVSRHDFDLNAWEVDNTCTDDAFTNKIRCYIDNSFKELTQRAGYCNFEEDLLKLLSLSSIILFKAVYHDEASLVSAIGKEAIKKYYDASKAKVYEDLEDFDLETLVPISRQLMEFRNNGSRIKLDAELTALQLKTSKSMQNTIQVLKSLAIQVKKPMKTELKESQLTASFVETFFSALFEYDDCLPYNANVREDNACKESYCPDYKIEFYEDDEKKFCNFYGEIKPKKSIKACKQKIYKDLYKLAIFAREEMKQTKLKAVMIAHIVHNCFNFYLMADKKDFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N1C3</accession>
    <name>A0A1C7N1C3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein C26H8.11c</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_09015</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000755">
        <property type="protein sequence ID" value="OBZ82935.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N1C3"/>
    <dbReference type="FunCoup" id="A0A1C7N1C3">
        <property type="interactions" value="15"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N1C3"/>
    <dbReference type="InParanoid" id="A0A1C7N1C3"/>
    <dbReference type="OrthoDB" id="506431at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd03443">
        <property type="entry name" value="PaaI_thioesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.129.10">
        <property type="entry name" value="Hotdog Thioesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029069">
        <property type="entry name" value="HotDog_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052061">
        <property type="entry name" value="PTE-AB_protein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006683">
        <property type="entry name" value="Thioestr_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47260">
        <property type="entry name" value="UPF0644 PROTEIN PB2B4.06"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47260:SF1">
        <property type="entry name" value="UPF0644 PROTEIN PB2B4.06"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03061">
        <property type="entry name" value="4HBT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54637">
        <property type="entry name" value="Thioesterase/thiol ester dehydrase-isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioesterase" evidence="2">
        <location>
            <begin position="105"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="11"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ82935.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="201" mass="22683" checksum="B01BDF212658C502" modified="2016-11-30" version="1">MTAIDTSVHYQPKDNQTHKKHDCQDHLADQENNIKLIRELRQSDEWHEVVAYEHLSDSARSHSLTATTLRGQNMIARRPVKFFNQDKTVCVMALHFGTHLCGHDGIIHGGLAATILDEMLAYVTIPSLPGHTGFTANLNVDYRRPILSDQWVIVRGELERLEGRKAWGKAHIETIDDVPVVLTEATALYISPRTQGPVTKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N1S8</accession>
    <name>A0A1C7N1S8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_10627</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001277">
        <property type="protein sequence ID" value="OBZ81324.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N1S8"/>
    <dbReference type="InParanoid" id="A0A1C7N1S8"/>
    <dbReference type="OrthoDB" id="2286663at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ81324.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="58" mass="6756" checksum="9E8D369CC4CE9549" modified="2016-11-30" version="1" fragment="single">YKEIYTKNFPAFQIDRLEKVIKKGMNKSDLAEWFYSPDCAQVTADAYGISVCVYPSRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N252</accession>
    <name>A0A1C7N252_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">FAS-associated factor 2-B</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">faf2-b_1</name>
        <name evidence="7" type="ORF">A0J61_09241</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000806">
        <property type="protein sequence ID" value="OBZ82709.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N252"/>
    <dbReference type="FunCoup" id="A0A1C7N252">
        <property type="interactions" value="961"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N252"/>
    <dbReference type="InParanoid" id="A0A1C7N252"/>
    <dbReference type="OrthoDB" id="1026733at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043130">
        <property type="term" value="F:ubiquitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036503">
        <property type="term" value="P:ERAD pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01767">
        <property type="entry name" value="UBX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.10">
        <property type="entry name" value="DNA helicase RuvA subunit, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049483">
        <property type="entry name" value="FAF1_2-like_UAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006577">
        <property type="entry name" value="UAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009060">
        <property type="entry name" value="UBA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001012">
        <property type="entry name" value="UBX_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050730">
        <property type="entry name" value="UBX_domain-protein"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23322:SF1">
        <property type="entry name" value="FAS-ASSOCIATED FACTOR 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23322">
        <property type="entry name" value="FAS-ASSOCIATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21021">
        <property type="entry name" value="FAF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14555">
        <property type="entry name" value="UBA_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00789">
        <property type="entry name" value="UBX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00594">
        <property type="entry name" value="UAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00166">
        <property type="entry name" value="UBX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46934">
        <property type="entry name" value="UBA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50033">
        <property type="entry name" value="UBX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="71"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="domain" description="UBX" evidence="6">
        <location>
            <begin position="327"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="260"/>
            <end position="289"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OBZ82709.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="430" mass="50242" checksum="6754AE97DAD060E8" modified="2016-11-30" version="1">MASSLTEEQTQKLTQYQAITQVENLEEGLSQLIDNDWNVERAIQHFYDNHGPRETPSRPTPPPRFSLFSLLFWPFGLAWSLLSFITRFLPLYRSIEHKRRKPPSVLAAEFKQQFESKYGPDHIPFFQGGYSEALEKAKRDLLFLLVVLHSSDHDETDRFCRETLTSTDLIQCIQDHRVLVWAGDVESAEAHKVSCTLKATTYPFLGLIALQSNKMTVVERMEGPAHPQELVSQLSHAIERHGASLQRLQYERDERERERQLRVDQDEAYHQSLKADQEKARRQQEEQEAKVQAERERQLVLEQKALLKQKREQYIQYLYAQLPDEPTHTPSAKINFRLADGDRVVRQFESQATVDTLYQFVEVYPLLKENKPKQPVEAPLDYHHQYQFTLHTTFPRMEFPPEESTPLVDIKNIWPSATLVVDQNDDDDEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N314</accession>
    <name>A0A1C7N314_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Reverse transcriptase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_08532</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000666">
        <property type="protein sequence ID" value="OBZ83417.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N314"/>
    <dbReference type="STRING" id="101091.A0A1C7N314"/>
    <dbReference type="InParanoid" id="A0A1C7N314"/>
    <dbReference type="OrthoDB" id="2245799at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.10.10">
        <property type="entry name" value="HIV Type 1 Reverse Transcriptase, subunit A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043502">
        <property type="entry name" value="DNA/RNA_pol_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050951">
        <property type="entry name" value="Retrovirus_Pol_polyprotein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37984:SF15">
        <property type="entry name" value="INTEGRASE CATALYTIC DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37984">
        <property type="entry name" value="PROTEIN CBG26694"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56672">
        <property type="entry name" value="DNA/RNA polymerases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="136"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ83417.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="136" mass="15788" checksum="6965A5C9C74B69A3" modified="2016-11-30" version="1" fragment="single">MKEEISCFIRQHPLPIEIDAEVAKNLNERIDNGIVEECLPLKQYHLLPLATEAGKPTELRICCDLRKVNLNISKTYSEGYAIPKIQNIFDRAFAKRKILTKLDLKQAYYSFPVDKASQEVLAFSYKGQHYKNHCRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N3L0</accession>
    <name>A0A1C7N3L0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Mitochondrial outer membrane protein iml2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">iml2_1</name>
        <name evidence="3" type="ORF">A0J61_08261</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000620">
        <property type="protein sequence ID" value="OBZ83693.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N3L0"/>
    <dbReference type="FunCoup" id="A0A1C7N3L0">
        <property type="interactions" value="82"/>
    </dbReference>
    <dbReference type="InParanoid" id="A0A1C7N3L0"/>
    <dbReference type="OrthoDB" id="2154985at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005741">
        <property type="term" value="C:mitochondrial outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019412">
        <property type="entry name" value="IML2/TPR_39"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31859">
        <property type="entry name" value="TETRATRICOPEPTIDE REPEAT PROTEIN 39 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31859:SF1">
        <property type="entry name" value="TETRATRICOPEPTIDE REPEAT PROTEIN 39C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10300">
        <property type="entry name" value="Iml2-TPR_39"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="317"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="369"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="233"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="727"/>
            <end position="754"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="233"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="246"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="728"/>
            <end position="738"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="739"/>
            <end position="753"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ83693.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="776" mass="89082" checksum="C87E3EBBDE95D7DD" modified="2016-11-30" version="1">MLRQLNNLSKFTTSSIKYAANNTAAVLISLSASSKDDPTLPSPQLLAYWISETQRGLDAFFNDDFDLATSIFLQHHQESPFHAVGYALIAYVEAMLGFESEKIQIALDRIAAAEVLARQFSKKARRKAWHSVNKSASTKKQHKHQEEEDPITFVLFDQSTNSPSKPFQKPSSPDIPYELLATNCMLMASTIQFLRNSWIEYMKAAYKLRKAYKVYEQMFESITGQKASEYAHQLKKTPHQTKQRASFTSLESSQSRSSSWTDKRTSMLHLFSDTIDVPNTKTPSLMLADTTTKPRPISTSDDPLDLIETSFSLIDTAVGSGIFFGIGLFSLIFSLLPPRVNKILNTLGFHSSRPFALHLLLKSFKSHGLYSSLSALSLLAYYTNLSLFIHPKLLPKSLSLDTARQILDRMKITFPQGKIWKLLEGKLCKMEGKTRRGVEILRDARRRENARVDLIISSSTYHYQQQKTNKKKSGSASGCSELAQLQALAVYEMGWGQIFLGDFFQAAETFFRLESMNNWSRAFYHYIATCCMFADEEYDKSALEFMQIPSILKRKRQLGGRLLPNEIFAERKIKHWRSKNKGHDLDGESLKHVVIVHPLWELIYLWNGFSQLDQDILLMMKQTMEDLLTNIPKEEIGADMSLLYLLLGVSVRELGDIDLADLYLRQSILAEDRASEDCWVIPHAFYEMACLCCFRMMQPAVSKQHQKKLYRESREWIVKSEKHLQHRQQQQQQQQQQQNTQYEPSVTSDNTGDSDWDSRLHVRCQLLIEKLEDFFC</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N4E7</accession>
    <name>A0A1C7N4E7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Pre-mRNA-processing factor 6</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">PRPF6</name>
        <name evidence="9" type="ORF">A0J61_08405</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000643">
        <property type="protein sequence ID" value="OBZ83546.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N4E7"/>
    <dbReference type="FunCoup" id="A0A1C7N4E7">
        <property type="interactions" value="678"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N4E7"/>
    <dbReference type="InParanoid" id="A0A1C7N4E7"/>
    <dbReference type="OrthoDB" id="440128at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071013">
        <property type="term" value="C:catalytic step 2 spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046540">
        <property type="term" value="C:U4/U6 x U5 tri-snRNP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045292">
        <property type="term" value="P:mRNA cis splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000244">
        <property type="term" value="P:spliceosomal tri-snRNP complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.10:FF:000649">
        <property type="entry name" value="mRNA splicing factor (Prp1/Zer1), putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.10:FF:000256">
        <property type="entry name" value="Probable pre-mRNA splicing factor prp1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.10:FF:000384">
        <property type="entry name" value="Probable pre-mRNA splicing factor prp1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003107">
        <property type="entry name" value="HAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010491">
        <property type="entry name" value="PRP1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045075">
        <property type="entry name" value="Syf1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11246">
        <property type="entry name" value="PRE-MRNA SPLICING FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11246:SF1">
        <property type="entry name" value="PRE-MRNA-PROCESSING FACTOR 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06424">
        <property type="entry name" value="PRP1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13428">
        <property type="entry name" value="TPR_14"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14559">
        <property type="entry name" value="TPR_19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13181">
        <property type="entry name" value="TPR_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00386">
        <property type="entry name" value="HAT"/>
        <property type="match status" value="14"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="4" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="6" id="KW-0802">TPR repeat</keyword>
    <feature type="domain" description="PRP1 splicing factor N-terminal" evidence="8">
        <location>
            <begin position="12"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="6">
        <location>
            <begin position="810"/>
            <end position="843"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="29"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="53"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF06424"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OBZ83546.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="910" mass="102333" checksum="D936B9492129757E" modified="2016-11-30" version="1">MFGVKDFMGKPAPPNYVAGLGRGATGFTTRSDIGPARESGVEADFAKAAAKEGEEDDDQYQDPDNEVGLFSSAPYEEDDEEADRVWDMIDAKMDERRKARREAREREELARYRLERPKISQQFADLKRQLTTIDESEWAAIPEVSDLVGKNRKRSKAPERFTPMPDSLIAAARDKTGYSTQLNEAEQKLGGIASTMAPPSEDMMTNFREIGQARDKVLGLKLDQVSSDSASGKTTIDPKGYLTDLNSVVVKSDAEIGDIKKARLLLNSVITTNPKHAPGWIAAARLEEVAGRPVHARNIIAKGCEQCPKNEDVWLEAARLNTVDNAKIILGDAVRHLPQSVKIWLKAVSLETESKAKKKVLRRALEFIPNSVKLWRSAINMEENPEDAKVLLSRAVELVPLSVDLWLALARLESYENAQKVLNKARAAIPSSHEIWIAAARLQEEHGKPEMVDRIIAMAAKALAQSGVMLDRDQWIEEAEKCEKNGSVATCQAIVKATIGMGVEDEDRKSTWMEDAESCVAHGSIETARAIYAYALKVFPGKPSIWQQAAYLEKSHGTPESLEELLQRAVKYCPQAEVLWLMGAKEKWLAGDVESARAILEEAFRANPNSEQIWLAAVKVESESDEYDRARKLLELARKESGTERVWMKSVMLERQMKNYEQCNVLLDEALKTFPTFDKLWMIKGQIEESQDNQAKAREVYNKAVKNCPKSIPLWILLSRLEYKMGMMTKARASLEKARFINPKTPELWVEAIRVEKNSNNLAVAKSLSAKALQECPSSGIIWTEVIFMEARPQRKARSVDALKKCEHDPVVVTAVARLFWTDRKIEKARNWFQKAIQIDPDQGDSFAWWYKFELQHGTQEQQSACIKRCVLAEPRHGEVWQSVAKDVANIGKKTEEILKLCADTLEQPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N4J0</accession>
    <name>A0A1C7N4J0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_07924</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000567">
        <property type="protein sequence ID" value="OBZ84032.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N4J0"/>
    <dbReference type="STRING" id="101091.A0A1C7N4J0"/>
    <dbReference type="InParanoid" id="A0A1C7N4J0"/>
    <dbReference type="OrthoDB" id="413572at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ84032.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="248" mass="28176" checksum="379B7678337CC226" modified="2016-11-30" version="1">MLGKLLCEWDPRSRYQYGELILPVILSGTLNELPTVQTTCKNSLSKVGLSCTQDLVGAGVLDAFPADEKEAEKIGLQHLVHMCYDKSAVYLIEQSTSFVQIRQETGLRSLKLLLEYATVDDLVRSIRKLMQCLLRVFATAENQTDIQEQVYAILMLLIDRLPSPEICLEALTLKLDRKRLVNEADGLPSDMTVRTVILFLERILTLINLSESETKRILSIVEKPYLKDYMNAETIEKKQQLVYSLHKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N4S9</accession>
    <name>A0A1C7N4S9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_07853</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000556">
        <property type="protein sequence ID" value="OBZ84100.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N4S9"/>
    <dbReference type="InParanoid" id="A0A1C7N4S9"/>
    <dbReference type="OrthoDB" id="2257835at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ84100.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="124" mass="14176" checksum="963DAFA024051CD9" modified="2016-11-30" version="1">MNIIFLLKDTFDNDLKVDIFLAEFKKLSAKPTQIQNDKTKVGNLMKLMIDRLVILGVSFPVICGLVQNGQMAFTYKMHITKDGEYDFVELGCFGTIRCTSDLMSLPIVMCYFENYFADNHKADN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N4V7</accession>
    <name>A0A1C7N4V7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Potassium channel tetramerisation-type BTB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_07797</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000548">
        <property type="protein sequence ID" value="OBZ84153.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N4V7"/>
    <dbReference type="STRING" id="101091.A0A1C7N4V7"/>
    <dbReference type="InParanoid" id="A0A1C7N4V7"/>
    <dbReference type="OrthoDB" id="2414723at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051260">
        <property type="term" value="P:protein homooligomerization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003131">
        <property type="entry name" value="T1-type_BTB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31758">
        <property type="entry name" value="BTB/POZ DOMAIN-CONTAINING PROTEIN YLR108C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31758:SF2">
        <property type="entry name" value="BTB_POZ DOMAIN-CONTAINING PROTEIN YLR108C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02214">
        <property type="entry name" value="BTB_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54695">
        <property type="entry name" value="POZ domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Potassium channel tetramerisation-type BTB" evidence="1">
        <location>
            <begin position="111"/>
            <end position="201"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02214"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ84153.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="364" mass="42608" checksum="5FFACEE68678557F" modified="2016-11-30" version="1">MESARQTTQVSNAFDINTSFTVNVCDRSFLLSWKSLVSDGPCNFFTRHFIKNRDVSRVLHIDRNLDTFIIIVRHLRGYPVAAKDHCQHQDLLSDAHYFGLKKLTQLLSQFVYLNVGGTSFRLRWDLFDRDGPRNYFTVFLKQSVFSPHTALGESPPIYIERDPNVFKDIIRHLQGYSISIRNEQHRQQLISDAKFYLLRKLSDKLKSSVSTQDLLLHYQDVRPQCFLLEDGVLYKQGQETFSLSIQFNDTHADLYFTNDLYNPTFELEYDIPLSKDNQWIISKQIQIDPDCAIIIQQPKRELTRSEFLQDLMLIQDHNQPTVRFCIEKAIARIQSIQQKAIYVSIEKMKVILSRKEANMVRGFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-06-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N510</accession>
    <name>A0A1C7N510_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_08214</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000612">
        <property type="protein sequence ID" value="OBZ83736.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N510"/>
    <dbReference type="InParanoid" id="A0A1C7N510"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ83736.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="64" mass="7465" checksum="AE2635FCFFDFF8DB" modified="2016-11-30" version="1">MAQQYSLQSKFGRESEFQNNMCLKKKEKGEELKDFDGWLFNMFGTPDSPSTLKKRAIGYEHAQD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N5J5</accession>
    <name>A0A1C7N5J5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Carboxylesterase NlhH</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">nlhH</name>
        <name evidence="4" type="ORF">A0J61_07684</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000534">
        <property type="protein sequence ID" value="OBZ84258.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N5J5"/>
    <dbReference type="STRING" id="101091.A0A1C7N5J5"/>
    <dbReference type="InParanoid" id="A0A1C7N5J5"/>
    <dbReference type="OrthoDB" id="19653at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049492">
        <property type="entry name" value="BD-FAE-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019826">
        <property type="entry name" value="Carboxylesterase_B_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050300">
        <property type="entry name" value="GDXG_lipolytic_enzyme"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48081">
        <property type="entry name" value="AB HYDROLASE SUPERFAMILY PROTEIN C4A8.06C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48081:SF33">
        <property type="entry name" value="KYNURENINE FORMAMIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20434">
        <property type="entry name" value="BD-FAE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00122">
        <property type="entry name" value="CARBOXYLESTERASE_B_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="7"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="50"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="80"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="domain" description="BD-FAE-like" evidence="3">
        <location>
            <begin position="178"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="412"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF20434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OBZ84258.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="412" mass="46527" checksum="2673F4359726C269" modified="2016-11-30" version="1" fragment="single">MFQLIKALIASGYIFSVIVSSVSIVCALDYPAVRSFLYANFRRHVMHAEILSGIAAEFSLQWIMLKLISIQLIKLFDYTLACLFYYIDLINIVGYGVLFYEMLTEIAVAQETIKKLDSTSQPLKSIVNTIDFRKLVNPFWTSKGIKKHPNITYATNEEIQEALKTTNYDYNQPSRMMLDVYTYGEKSKARPVLMLIHGGAWRIGSKNTLYPHEKILLTENNWVVVNINYRLAPVNAYPTHLCDVKRAIRWVKQNIASFGGNPDFIVLSGDSAGGHLSAMASMTMNDPQFQPGFEEVDTSVRGVVSLSGALDMMSAPHHADYFCKQVSNLDRVDMEFLSKHSPAQVIPRAKEQNCIVPFLLIAGNRDSLVEIDINNKFKATFDEGKRYDLYQIQENHSLTFSPLVTGSPDECT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N5L8</accession>
    <name>A0A1C7N5L8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_08017</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000581">
        <property type="protein sequence ID" value="OBZ83936.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N5L8"/>
    <dbReference type="InParanoid" id="A0A1C7N5L8"/>
    <dbReference type="OrthoDB" id="2254372at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="35"/>
            <end position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ83936.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="170" mass="18977" checksum="156F0D5A6CE68CE0" modified="2016-11-30" version="1">MPISLGRSGTIKEEKPKLKRSSTLSRVKSFGSKLIRSNSQYRLSHQPTKTPPPPPLPSSSVSLKSDDSEEDQVVTPTTGSFSLHDDDKHSMVAPSPYVNQSTPVLPELHLSKTNNTIFLAEEETALTTVSLVRYHIADAFRQVDQEIEQEFDLSHQHMLDSIYASPQYTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N623</accession>
    <name>A0A1C7N623_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Interferon-related developmental regulator 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">IFRD2</name>
        <name evidence="4" type="ORF">A0J61_07461</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the IFRD family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000503">
        <property type="protein sequence ID" value="OBZ84487.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N623"/>
    <dbReference type="FunCoup" id="A0A1C7N623">
        <property type="interactions" value="37"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N623"/>
    <dbReference type="InParanoid" id="A0A1C7N623"/>
    <dbReference type="OrthoDB" id="18978at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039777">
        <property type="entry name" value="IFRD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007701">
        <property type="entry name" value="Interferon-rel_develop_reg_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12354">
        <property type="entry name" value="INTERFERON-RELATED DEVELOPMENTAL REGULATOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12354:SF1">
        <property type="entry name" value="INTERFERON-RELATED DEVELOPMENTAL REGULATOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05004">
        <property type="entry name" value="IFRD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Interferon-related developmental regulator N-terminal" evidence="3">
        <location>
            <begin position="33"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="21"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="288"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="330"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="416"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="299"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="330"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="450"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008828"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF05004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OBZ84487.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="450" mass="49988" checksum="90A1A95B0D45EA97" modified="2016-11-30" version="1" fragment="single">MSKSLRKKVVKQQSRLAALDLLGTPTTSEVESDGDSETSSVLGDSVLPDVDESVLEDDIRHCVNELGEKRASSREAALTNLSKLMRHYYCGSFFDNNPSAQEALLQLLVRLVRKPGTTEEAVLAARAIGLAFVNAGEQSDSEQESLYVMVLPYLKQVIKDSNQVELKCQAIDTLATMTFAAASTSSTKGALDYLYKILISNASQIQPDESELSTNDLLLVMEATLRAYGLLYASVFGQGRYSIDDAWDEWQSYVFVQGAMPAHLDLLESKSKDVRVAAGENVALMYECSHAPKNNGQSEDTEEEEKEDMSEYEELDDLIDILQRLANESSRRVNKQDRKEQKSAFRDILKSVQTGHRPKERLKLGRQRFVFRGWAQIIELHAFRSILGAGLANHFESNGLVQGVFDNSVDDDDSDGFDFSNVDSGVEDIPESELGTLESTKSMNRSKHAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N6A4</accession>
    <name>A0A1C7N6A4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_07382</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000495">
        <property type="protein sequence ID" value="OBZ84567.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N6A4"/>
    <dbReference type="InParanoid" id="A0A1C7N6A4"/>
    <dbReference type="OrthoDB" id="2284644at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="46"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="94"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="55"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="100"/>
            <end position="114"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ84567.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="131" mass="15481" checksum="E5611012D7BF0300" modified="2016-11-30" version="1">MSSRLAKQSLDLLTSTNNKKVEKTDSKKIKLPKTNKGIKKVKYENRYGRHQKTRLRQEEVKKRENPIDRLHEQEQLEEERLKRNVRIMRMALRSSPLEKKIHKTAKRNAKRTKKWSSEVHGSDGDTDSDSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N7M9</accession>
    <name>A0A1C7N7M9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">BAG domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_07323</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000487">
        <property type="protein sequence ID" value="OBZ84629.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N7M9"/>
    <dbReference type="InParanoid" id="A0A1C7N7M9"/>
    <dbReference type="OrthoDB" id="333905at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051087">
        <property type="term" value="F:protein-folding chaperone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.120">
        <property type="entry name" value="BAG domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036533">
        <property type="entry name" value="BAG_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003103">
        <property type="entry name" value="BAG_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02179">
        <property type="entry name" value="BAG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63491">
        <property type="entry name" value="BAG domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51035">
        <property type="entry name" value="BAG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BAG" evidence="2">
        <location>
            <begin position="376"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="41"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="97"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="128"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="219"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="447"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="46"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="140"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="164"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="222"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="255"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="307"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="449"/>
            <end position="468"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ84629.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="468" mass="54336" checksum="531FA6DF2ACC343D" modified="2016-11-30" version="1">MNCLCYLHYVQRKSHGCCPAXLKAKQEEEYLRQKLEQEHILVAQQAEEEEKEEEDGESDEYFEEDEEDEGYSKYRTQQLEELLRHVFAHHPQYFEEDYNEKAPLHTSQTDSEDNHDLATDEIWKYLSDQKHDLESPRTALLSTGQKETSTPSDVKSKLVQGDGQEYEVEHESDESDAESERQDSSEATSSTSTPLPAVQDHVVSLQDLIQKLASEPVVVGQQAASEQLRDTQPSSFYSDEPKPSGIWINSQPPSENKKTKYHNEEKQEKDESYLPQHIFTEAEPTPTRETIPDVPFNMEEDSVIQVNKDEAKKTKEESDFVDSVAAEQKKQETNPQKAKQLESLNAIARELEDDSDLVKRWNQVLRSKLNFTKQPEGTLLVTASTDANRRYLGSEDEITRLMLKLDAVDSMGDEQIREKRRTLVKKCEHMVDVLDRMKHLQWQNAFKKLEKKKKNNRRRKSKKNKYKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N7Y1</accession>
    <name>A0A1C7N7Y1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_06870</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000435">
        <property type="protein sequence ID" value="OBZ85088.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N7Y1"/>
    <dbReference type="STRING" id="101091.A0A1C7N7Y1"/>
    <dbReference type="InParanoid" id="A0A1C7N7Y1"/>
    <dbReference type="OrthoDB" id="10267127at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014867">
        <property type="entry name" value="Spore_coat_CotH_CotH2/3/7"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40050">
        <property type="entry name" value="INNER SPORE COAT PROTEIN H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40050:SF1">
        <property type="entry name" value="INNER SPORE COAT PROTEIN H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08757">
        <property type="entry name" value="CotH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008889534" evidence="1">
        <location>
            <begin position="21"/>
            <end position="545"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ85088.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="545" mass="61253" checksum="9E5418AEE0B9D730" modified="2016-11-30" version="1">MKFFSSAIVGSVFALTMAHAADVTYSVIAFPESGETVVVNVDNTAHPLQQSSLSQNLFSGVAPYGSQYNYAYSASSGQRPESTVRHLASESVVATGNEFFNRSKTVYDVPDFPRAYNAVYPSYESAMSRSNEIATILLNADLNSLEEILEAPTEDHKYAQVYNMTYISSDAVFNFQGAGIRNSGQSSKDYAKQSYKIKLNKYNKGAGAKLFNRKSLKLRAEPVDPTMVREKLYMDSLAASGAATLNGHWVRLFVNNEPFGLYLMIDDANDKLFENLVHGGAKTNATGPIYKGNAMSPSREANLVYKGPNNSSYDFSDVYILEEAGRDKAVTKKSYTEPIITFMELLNHTVIGTDAQTPGNISDLMDSTDHTMLHTALSFLTGSWDGYWYQASNYYLHQNRENFKWYLVSYDFDETFGNNLEKPELMTVTYQNYTRAGSSRPLVDAFIKSPYYQPHFEEMLKTITKSFFNPQTIKARLDAWHEMLKEDVAWDYSLERRSPGEKPKFTVEKFSKNLYSTVDGTVGILEWVSNRTSSLQSQLNFSLTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N8B4</accession>
    <name>A0A1C7N8B4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Alpha-and gamma-adaptin-binding protein p34</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">Aagab</name>
        <name evidence="1" type="ORF">A0J61_06638</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000411">
        <property type="protein sequence ID" value="OBZ85307.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N8B4"/>
    <dbReference type="STRING" id="101091.A0A1C7N8B4"/>
    <dbReference type="InParanoid" id="A0A1C7N8B4"/>
    <dbReference type="OrthoDB" id="10261384at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11960">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019341">
        <property type="entry name" value="Alpha/Gamma-adaptin-bd_p34"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14659">
        <property type="entry name" value="ALPHA- AND GAMMA-ADAPTIN-BINDING PROTEIN P34"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14659:SF1">
        <property type="entry name" value="ALPHA- AND GAMMA-ADAPTIN-BINDING PROTEIN P34"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10199">
        <property type="entry name" value="Adaptin_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ85307.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="298" mass="34172" checksum="B3D980BC8EBB8C57" modified="2016-11-30" version="1">MLRNKILVTSRPKGKTVEFVKDIFTCSKQDFPQSLVDKRLKETQDDYVGVCIPYEIDTKYYTAKVDFWMDEIDAVSEKETIKAYCEKEGDISRVIDAFVFLFDKDKPDSFDTLSLWKPFLEQSDPSICLCVGTSTQKTILSMEKDVEINDWCISNGFDYVDMDETTDTPFDKVGIELALDILQTNLWDGMQKKKSKHASEHEEEEALLRDIQALKLQHDVLAPSDDDWEEEDYADMPSKDEISQMREELFGDIDGEDGLDKAFEAIQAMREQGKNLSDEERRKMAAKVALSFAAQLGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N9R0</accession>
    <name>A0A1C7N9R0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="13">EH domain-containing protein 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">Ehd2</name>
        <name evidence="13" type="ORF">A0J61_06090</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
            <orientation evidence="1">Cytoplasmic side</orientation>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Endosome membrane</location>
            <topology evidence="2">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000351">
        <property type="protein sequence ID" value="OBZ85862.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N9R0"/>
    <dbReference type="STRING" id="101091.A0A1C7N9R0"/>
    <dbReference type="InParanoid" id="A0A1C7N9R0"/>
    <dbReference type="OrthoDB" id="1716625at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010008">
        <property type="term" value="C:endosome membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006897">
        <property type="term" value="P:endocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016197">
        <property type="term" value="P:endosomal transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00052">
        <property type="entry name" value="EH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd09913">
        <property type="entry name" value="EHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000147">
        <property type="entry name" value="EH domain-containing protein 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.268.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040990">
        <property type="entry name" value="DUF5600"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022812">
        <property type="entry name" value="Dynamin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045063">
        <property type="entry name" value="Dynamin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000261">
        <property type="entry name" value="EH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031692">
        <property type="entry name" value="EHD_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030381">
        <property type="entry name" value="G_DYNAMIN_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11216:SF31">
        <property type="entry name" value="AT21416P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11216">
        <property type="entry name" value="EH DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18150">
        <property type="entry name" value="DUF5600"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00350">
        <property type="entry name" value="Dynamin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12763">
        <property type="entry name" value="EH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16880">
        <property type="entry name" value="EHD_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00195">
        <property type="entry name" value="DYNAMIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00027">
        <property type="entry name" value="EH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50031">
        <property type="entry name" value="EH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51718">
        <property type="entry name" value="G_DYNAMIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0106">Calcium</keyword>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6" id="KW-0967">Endosome</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Dynamin-type G" evidence="12">
        <location>
            <begin position="73"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="domain" description="EH" evidence="10">
        <location>
            <begin position="458"/>
            <end position="545"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="11">
        <location>
            <begin position="490"/>
            <end position="525"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="13"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004413"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022753"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51718"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="OBZ85862.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="545" mass="62483" checksum="1B266E484CA6AFC4" modified="2016-11-30" version="1">MFKNSIKKEKSMKSPSQKGSSANWNEDEYAMIIEDIKRVYRSKIKPLEVTYNFEGSNVIYLCFHSAPLTDSDIEAKPMVLLIGQYSTGKTTFIRYLLDKKYPGEHIGVEPTTDRFLAVMNGKEDRVIPGNAAAVNQELPFRGLNHFGQAFLSRFQVSETPSPVLENMTIIDTPGILAGDKQRIERGYDFTQITEWFAQRADLILLMFDSYKLDISNEFKMAIHSLRGQEEKVRVVLNKSDMVSQQQLMRVYGAMMWSLGKVVQTPEVMRVYISSFWTEKPPNCFEDCRELIEAESKDLLMDLKELRRNAAIRKVNEIVKRARLARVHALIISHLKKEMPSMFGKKKKQEALLNRLDQEFIKIQNKYHLPAGDFPNPDKFKQNLAMYDMDKFKSLKEDLIQRVDEALAVDFPKIMSRFPTGNPELEKSQLNPFDMPEANMEEVVHGQLPASFWEFNNLDKNSYMPTFQSLHPRDGKVSGANVKPVLEESGLDNGRLADIWRLSDWDSDGYLDADQFGVAMHLIKAVQLGAQLPEKLPSSMMPGRKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N9W6</accession>
    <name>A0A1C7N9W6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_06545</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000400">
        <property type="protein sequence ID" value="OBZ85406.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N9W6"/>
    <dbReference type="InParanoid" id="A0A1C7N9W6"/>
    <dbReference type="OrthoDB" id="2287001at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="89"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="157"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ85406.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="157" mass="17688" checksum="3D2C05F876EBD819" modified="2016-11-30" version="1" fragment="single">KAITVESDFAPTRAKCSPTRNRKIFIANIVILYDFMVDFMSTINNTHIVLETLENEGAKQSATSKPVKRTRPRTSIVRLSYLWDKVSDGGEDTKCRSKKSTKNPGHSNSLTEEHKAHILNLIDDNTQVIADFFLEDSSLTKSAFYGYMNEAAIILKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NA65</accession>
    <name>A0A1C7NA65_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Protein YOP1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">REEP4</name>
        <name evidence="3" type="ORF">A0J61_06379</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the DP1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="1">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000382">
        <property type="protein sequence ID" value="OBZ85569.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NA65"/>
    <dbReference type="STRING" id="101091.A0A1C7NA65"/>
    <dbReference type="InParanoid" id="A0A1C7NA65"/>
    <dbReference type="OrthoDB" id="434647at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004345">
        <property type="entry name" value="TB2_DP1_HVA22"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12300">
        <property type="entry name" value="HVA22-LIKE PROTEINS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03134">
        <property type="entry name" value="TB2_DP1_HVA22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0675">Receptor</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="35"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="243"/>
            <end position="263"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU362006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ85569.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="263" mass="29939" checksum="D10F7072FD1374B3" modified="2016-11-30" version="1">MFSAAIYFCVKLILLQLYPAYICYKALKTNNQQEFRSLLTFWIVSITYLSFEYFSDIFLFWLPLYTEIKLILVLWLILPQTQGSSVFYANYLDPFLNTHETDIDNALLEIQAKLKETIALYGKQTLLQVKKWIMGMVFKNQETTVNSSETITHAKSPVEDRAGNNIINPYDLFSTLISSTANRFQSPSESTTETPVVEKLERSDSHDSFVNIKEGANATAVTQDVPPQEVASPSWGNYLAGWIRKPSSSSSVPTMSTEHKKQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NA83</accession>
    <name>A0A1C7NA83_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Beta-etherase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">ligE</name>
        <name evidence="2" type="ORF">A0J61_05906</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000334">
        <property type="protein sequence ID" value="OBZ86042.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NA83"/>
    <dbReference type="STRING" id="101091.A0A1C7NA83"/>
    <dbReference type="InParanoid" id="A0A1C7NA83"/>
    <dbReference type="OrthoDB" id="4951845at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1050.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036282">
        <property type="entry name" value="Glutathione-S-Trfase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004045">
        <property type="entry name" value="Glutathione_S-Trfase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054416">
        <property type="entry name" value="GST_UstS-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22041">
        <property type="entry name" value="GST_C_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13409">
        <property type="entry name" value="GST_N_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47616">
        <property type="entry name" value="GST C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50404">
        <property type="entry name" value="GST_NTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GST N-terminal" evidence="1">
        <location>
            <begin position="11"/>
            <end position="99"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ86042.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="243" mass="27851" checksum="195723F8A544959E" modified="2016-11-30" version="1">MVATIQLYDLELLGLPKTVFSCNTLKTRIALNLKGLPFETKWLDFATVKEVIPTLTKQNPELKRPTVPVIVDSISGQDKVIQDSYDIAVYLEKQYPNTPSLFHNNPGVHRFFQQYCESVLLLPLFKLVMFIIHKQCGPDVLQDWWREDRERMFGCSLDVFAGNRDDNILAVKNALLPIIKVLKEFPFMTGEQVGWADVVLAADFKMMAALDPVTFESVFLSGFETPADDVLIQNWWKRMSVYI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NAU1</accession>
    <name>A0A1C7NAU1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Pirin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">PIR</name>
        <name evidence="8" type="ORF">A0J61_07446</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </cofactor>
        <text evidence="4">Binds 1 Fe cation per subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the pirin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000502">
        <property type="protein sequence ID" value="OBZ84504.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NAU1"/>
    <dbReference type="STRING" id="101091.A0A1C7NAU1"/>
    <dbReference type="InParanoid" id="A0A1C7NAU1"/>
    <dbReference type="OrthoDB" id="198735at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02247">
        <property type="entry name" value="cupin_pirin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd02909">
        <property type="entry name" value="cupin_pirin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.120.10:FF:000055">
        <property type="entry name" value="pirin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="entry name" value="Jelly Rolls"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012093">
        <property type="entry name" value="Pirin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008778">
        <property type="entry name" value="Pirin_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003829">
        <property type="entry name" value="Pirin_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13903:SF8">
        <property type="entry name" value="PIRIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13903">
        <property type="entry name" value="PIRIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02678">
        <property type="entry name" value="Pirin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05726">
        <property type="entry name" value="Pirin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006232">
        <property type="entry name" value="Pirin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="RmlC-like cupins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0408">Iron</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pirin N-terminal" evidence="6">
        <location>
            <begin position="30"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="domain" description="Pirin C-terminal" evidence="7">
        <location>
            <begin position="180"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="64"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="66"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="108"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="110"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008416"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR006232-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003457"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF02678"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF05726"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OBZ84504.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="302" mass="33617" checksum="651D3E604FF594C2" modified="2016-11-30" version="1">MTTPVSNNERVPRTITKSVLSREQMDGVGARVYRSIGSYALRNLDPFLMLDEFDVEAPGGFPDHPHRGFETVTYMLEGEFLHEDFKGHKGRIGPGDLQWMSAARGIVHAEVPATNTRAHGLQLWVNLSSKDKMSEPNYQEFPKEKVVHVQPEEGIAIKVIAGESYGAKSPVMTRTPTMFIDVKLKKGKKMEQVIPKDYAGFIYTIAGSALYGGSQHASEAHHTLVLSNNEGDYIPVESTSDDCHFVVIAGQPIREPVVQHGPFVMNTQQEIYQAFADYQHGKNGFEGAPGWTSSIRSRWGRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NBF5</accession>
    <name>A0A1C7NBF5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF6729 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_05984</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000341">
        <property type="protein sequence ID" value="OBZ85966.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NBF5"/>
    <dbReference type="STRING" id="101091.A0A1C7NBF5"/>
    <dbReference type="InParanoid" id="A0A1C7NBF5"/>
    <dbReference type="OrthoDB" id="2226101at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046616">
        <property type="entry name" value="DUF6729"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20499">
        <property type="entry name" value="DUF6729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF6729" evidence="2">
        <location>
            <begin position="47"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="16"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF20499"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ85966.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="363" mass="42632" checksum="0E465E59657D0ACB" modified="2016-11-30" version="1">MSDSAKDQENDHNDLQQDDQSDAEEEFISDSLPEDSFLISYFHEIQSTFWIELMMPYFMLENKKVESFYRPRILLWTPHLLTEERLGGLKCSSCNSKMETKGFNRNPHARRIVDLTICFYLMSMRYRCLSPRCGNIVNGHDGSIVKQLLLELQMRFPSFLTHKGGVSKAAADLLKPCIQNSVDPERFRKFLLEMHHLRHNRLELQYLLSFFRKRNSIARRFHQSELKTYSAFEDQRQYSDYVPTSTYIRILYTAIIETLRPKMGKHMILLDGKLLKGNHSFKFPKHVTRIEETSVFTALYTVTNEHEKIVQQSLVPSKALSYLRYPFEKMHEAYSLYGHEMPIAFFTDNIKGDKSFLEAFSNG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NBV8</accession>
    <name>A0A1C7NBV8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">N-alpha-acetyltransferase 50</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">naa50</name>
        <name evidence="4" type="ORF">A0J61_05353</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000286">
        <property type="protein sequence ID" value="OBZ86607.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NBV8"/>
    <dbReference type="FunCoup" id="A0A1C7NBV8">
        <property type="interactions" value="245"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NBV8"/>
    <dbReference type="InParanoid" id="A0A1C7NBV8"/>
    <dbReference type="OrthoDB" id="47374at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031415">
        <property type="term" value="C:NatA complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016747">
        <property type="term" value="F:acyltransferase activity, transferring groups other than amino-acyl groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007064">
        <property type="term" value="P:mitotic sister chromatid cohesion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd04301">
        <property type="entry name" value="NAT_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.630.30:FF:000006">
        <property type="entry name" value="Putative n-alpha-acetyltransferase 50"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051556">
        <property type="entry name" value="N-term/lysine_N-AcTrnsfr"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42919">
        <property type="entry name" value="N-ALPHA-ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42919:SF8">
        <property type="entry name" value="N-ALPHA-ACETYLTRANSFERASE 50"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="3">
        <location>
            <begin position="5"/>
            <end position="156"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OBZ86607.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="156" mass="17833" checksum="6C28566C4437F30A" modified="2016-11-30" version="1">MPAHIDLGDVTKNNLGQVRVLHKALFPVNYGENFYNELLEAGEFAKLAYYNDVCVGTVCCRREVDESNPEKVKIYMMTLGVLEPYRHLGIGSALLKHIIQQAKLSEDVSQIYLHVQVSNTAAADFYKKNEFQVISTEKDYYKHIEPRDAYLLAYVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NBX8</accession>
    <name>A0A1C7NBX8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">A0J61_05859</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1 8">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000329">
        <property type="protein sequence ID" value="OBZ86096.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NBX8"/>
    <dbReference type="STRING" id="101091.A0A1C7NBX8"/>
    <dbReference type="InParanoid" id="A0A1C7NBX8"/>
    <dbReference type="OrthoDB" id="1470350at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050196">
        <property type="entry name" value="Cytochrome_P450_Monoox"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24291:SF50">
        <property type="entry name" value="BIFUNCTIONAL ALBAFLAVENONE MONOOXYGENASE_TERPENE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24291">
        <property type="entry name" value="CYTOCHROME P450 FAMILY 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 7 8" id="KW-0349">Heme</keyword>
    <keyword evidence="5 7 8" id="KW-0408">Iron</keyword>
    <keyword evidence="3 7 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 8" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="4 8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" description="axial binding residue" evidence="7">
        <location>
            <position position="478"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OBZ86096.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="534" mass="62102" checksum="A1E260ED1A2DADE8" modified="2016-11-30" version="1">MSLPMSTNYLFVKESIWTIWKSHRHNGFSKTQNRKYLIGTAIALIFAYLVQDRFLKPPRKLRHIPYVGWIPVLLSSIRRESAYVYGQKNIHPKLKSKEIKDIYARSSDLGWIVYLLNPKDIKQVLLKPDLFPKINLSEGYENTLTNRFNDGHSLFFSNGPEWKGMKSVISPVFSRSLPVEMFGERASRLFERMESIGNVIEVSNLMRRYTLDVIGRAAFGIDFEAIADPNCEWIALYDIINQGIQDPFFFTFPDLEQNHLWMFGDRIALHHRLDKLMEKIDKVIEQRKEELRNGNIESSAKNDMLTTMIKELEKKNGIIREEQIKSNFCFFFLAGHDSTTNAICFALYYFAVYPEIQQRAREEVNRVLGTEPKDVLPDMNQIKQMEYIYMVIKEVLRIHPPAPRSGPRRAKEDTVISGKFIPKNSIVAIDIYNAHHHQDVWENENVFDPERFRTTNYDGRHAGKGISWLPFGSGPRQCVGMNFSLTEQRVVLCMMLRKFNWSLPENSPHNHGVLTSGSFLAGPKNMEIKFESRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NCD7</accession>
    <name>A0A1C7NCD7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">WHIM1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">A0J61_05185</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000273">
        <property type="protein sequence ID" value="OBZ86763.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NCD7"/>
    <dbReference type="STRING" id="101091.A0A1C7NCD7"/>
    <dbReference type="InParanoid" id="A0A1C7NCD7"/>
    <dbReference type="OrthoDB" id="29773at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037185">
        <property type="entry name" value="EmrE-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028942">
        <property type="entry name" value="WHIM1_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13146">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13146:SF1">
        <property type="entry name" value="SUGAR PHOSPHATE TRANSPORTER DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15612">
        <property type="entry name" value="WHIM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103481">
        <property type="entry name" value="Multidrug resistance efflux transporter EmrE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="7"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="46"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="109"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="134"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="158"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="187"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="221"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="domain" description="WHIM1" evidence="5">
        <location>
            <begin position="393"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="556"/>
            <end position="583"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="556"/>
            <end position="567"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF15612"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OBZ86763.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="583" mass="66719" checksum="6414D279A0BEDE2E" modified="2016-11-30" version="1">MNINREMMYIAFHQVMFLMTGLSTTLGTQWLFYHKAATGDSYLAQLSQYLGMVMVGLLIPILLRNKQKAYQRLNQEDDQVAMTTLASVTEQEPSKYIEGPMPYRSVMKLAVLDVFANFCVTVGFAIVGSGMYQVIYSSVVIWCAILTWFLMNRTLSRVQWVAIFGTSAGLAVSSFGDFSVETETGSLLLFGTLMTLGGTFFYSCVYVYSDYIMSQQKPPPLAARVCFTTGIYTSCISCVWIAIYTLPRFSQLIQPTAPLETVMGMYLMVSLSNACHSWNYYELIDRTGSVATGILQGLRAVLIYVISDAWYCSSDPAQCFTPYKGLGSMLVIGCVLLFTELTQAIELEESELVHQIICASLGNCLNRKHPVESYKVAFQQLVQEKIKSLDIDLTLNPLTKQPFKALPIDTKLYLLQCLIEWQLQDSQAIRQSISNSIYTLSPIGTDSKKRLYWQFGESCWIWREKPHAKQQLSDWETVCRDRDSLTALVDSLSDQQTAERRLRHYIIEHLYELADEEEKKRQRKERAELRKSMPIIITTPQLRSRHHVNYNYDPMLEIEQDQEEEDSKPETTPTRWSQRLKKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NCM8</accession>
    <name>A0A1C7NCM8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Flavin reductase like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_05191</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000274">
        <property type="protein sequence ID" value="OBZ86758.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NCM8"/>
    <dbReference type="STRING" id="101091.A0A1C7NCM8"/>
    <dbReference type="InParanoid" id="A0A1C7NCM8"/>
    <dbReference type="OrthoDB" id="2015405at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042602">
        <property type="term" value="F:riboflavin reductase (NADPH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.110.10">
        <property type="entry name" value="Electron Transport, Fmn-binding Protein, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002563">
        <property type="entry name" value="Flavin_Rdtase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050268">
        <property type="entry name" value="NADH-dep_flavin_reductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012349">
        <property type="entry name" value="Split_barrel_FMN-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30466">
        <property type="entry name" value="FLAVIN REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30466:SF1">
        <property type="entry name" value="FMN REDUCTASE (NADH) RUTF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01613">
        <property type="entry name" value="Flavin_Reduct"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00903">
        <property type="entry name" value="Flavin_Reduct"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50475">
        <property type="entry name" value="FMN-binding split barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Flavin reductase like" evidence="2">
        <location>
            <begin position="37"/>
            <end position="193"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00903"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ86758.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="333" mass="37875" checksum="D034C1DA0ECE00A4" modified="2016-11-30" version="1">MDVRLECFVSRKSRPWINSVRLFSAHSGLTENVRGIMRKVPLPVVVVTTSRPEDRNHRRGITVASFTSVCLHPQPLVSFCVRTPSRASDLLHSSGSMVLNLLSHEQVQQSVAFSSPDKDQFKDVPFYDDPVTGLPVLIGTLGAMHCKKFKVMELGDHELWIAQVLKVEEGVGGEHGVREEAQPLLYYERNYCSVGDQVFMKSFMDNQDQSAHNWMHRAHLRMAWNMIRELGPVAAEPAIKEALRTHFSHAKSNNKDYHETITSFYIALVSAAINSYKGRDSHDFFALVEKFPQLLDVKLIEQYYSPHILYAKDAKETFVKPDLQPLPTQLIEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NCN6</accession>
    <name>A0A1C7NCN6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">Nicotinamide-nucleotide adenylyltransferase</fullName>
            <ecNumber evidence="15">2.7.7.1</ecNumber>
            <ecNumber evidence="15">2.7.7.18</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">A0J61_05167</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="14 15">
            <text>beta-nicotinamide D-ribonucleotide + ATP + H(+) = diphosphate + NAD(+)</text>
            <dbReference type="Rhea" id="RHEA:21360"/>
            <dbReference type="ChEBI" id="CHEBI:14649"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="EC" id="2.7.7.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13 15">
            <text>nicotinate beta-D-ribonucleotide + ATP + H(+) = deamido-NAD(+) + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:22860"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57502"/>
            <dbReference type="ChEBI" id="CHEBI:58437"/>
            <dbReference type="EC" id="2.7.7.18"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 15">Cofactor biosynthesis; NAD(+) biosynthesis; NAD(+) from nicotinamide D-ribonucleotide: step 1/1.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3">Cofactor biosynthesis; NAD(+) biosynthesis; deamido-NAD(+) from nicotinate D-ribonucleotide: step 1/1.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 15">Belongs to the eukaryotic NMN adenylyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.1" evidence="15"/>
    <dbReference type="EC" id="2.7.7.18" evidence="15"/>
    <dbReference type="EMBL" id="LUGH01000272">
        <property type="protein sequence ID" value="OBZ86778.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NCN6"/>
    <dbReference type="FunCoup" id="A0A1C7NCN6">
        <property type="interactions" value="172"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NCN6"/>
    <dbReference type="InParanoid" id="A0A1C7NCN6"/>
    <dbReference type="OrthoDB" id="422187at2759"/>
    <dbReference type="UniPathway" id="UPA00253">
        <property type="reaction ID" value="UER00332"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000309">
        <property type="term" value="F:nicotinamide-nucleotide adenylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004515">
        <property type="term" value="F:nicotinate-nucleotide adenylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009435">
        <property type="term" value="P:NAD+ biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd09286">
        <property type="entry name" value="NMNAT_Eukarya"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.620:FF:000074">
        <property type="entry name" value="Nicotinamide-nucleotide adenylyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004821">
        <property type="entry name" value="Cyt_trans-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051182">
        <property type="entry name" value="Euk_NMN_adenylyltrnsfrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005248">
        <property type="entry name" value="NadD/NMNAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045094">
        <property type="entry name" value="NMNAT_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00482">
        <property type="entry name" value="nicotinate (nicotinamide) nucleotide adenylyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12039">
        <property type="entry name" value="NICOTINAMIDE MONONUCLEOTIDE ADENYLYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12039:SF0">
        <property type="entry name" value="NICOTINAMIDE-NUCLEOTIDE ADENYLYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01467">
        <property type="entry name" value="CTP_transf_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52374">
        <property type="entry name" value="Nucleotidylyl transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 15" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="11 15" id="KW-0520">NAD</keyword>
    <keyword evidence="9 15" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8 15 17" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="12" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6 15" id="KW-0662">Pyridine nucleotide biosynthesis</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 15 17" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Cytidyltransferase-like" evidence="16">
        <location>
            <begin position="43"/>
            <end position="235"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004658"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007064"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00048721"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00049001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="RuleBase" id="RU362021"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF01467"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="OBZ86778.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="265" mass="30555" checksum="60444A52A8F3CF61" modified="2016-11-30" version="1">MASTPLGERNDIIFDKQDDDYLFPRQLIPETMKNENKTPLVIVACGSYSPITYLHLRMFEMARDHFNGRLDDEYELIAGYYSPVSDAYKKEGLVEAKHRVKMCELAVESTSDWLMVDSWESRQPIYQRTAVVLDHFDHELNQIGRGIKMSSGEYKKVKIMLLAGGDLMASFGHPGVWSSEDLHHIVGKYGCVIIERTGTDVYGFLLSHDILYQYRLNVLIIKQLIHNDISSTKIRLFVKRGMSIKYLLPNPVIDYIAENRLYHTD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7ND50</accession>
    <name>A0A1C7ND50_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Septin-2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">Sept2</name>
        <name evidence="3" type="ORF">A0J61_05460</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000295">
        <property type="protein sequence ID" value="OBZ86486.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7ND50"/>
    <dbReference type="STRING" id="101091.A0A1C7ND50"/>
    <dbReference type="InParanoid" id="A0A1C7ND50"/>
    <dbReference type="OrthoDB" id="5340910at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030379">
        <property type="entry name" value="G_SEPTIN_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18884">
        <property type="entry name" value="SEPTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00735">
        <property type="entry name" value="Septin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Septin-type G" evidence="2">
        <location>
            <begin position="68"/>
            <end position="193"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU004560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00735"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ86486.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="343" mass="39027" checksum="495BDFDF72004E09" modified="2016-11-30" version="1">MQNTIDTYDLLSVENSLVQTEKNQNFPFRIIICGDSGIGKSTLANSLTLSENTSRNPSLEPVEICSNNFCIVDTCGYGVLSKAEVVFQQVRSYIERQFEKTSQLFSPVIKEEDRFISVLQQASQCFTHVDACLYLIMGRLKPVDVEYMRTIQDLVNIIPIVIQTDLTLRPEVMTKRRMEIADYLEANRIKCFQSEPFVLDWSVMSNSFHGTLSLRQYLLQQLCGQLRQSTVQKFIAWRKQALSNSTVLSVYSSQSSGNNSMLAGSSDSGGGVSNAALEEKNKIRISQYITHRRHSMEKELLIQEKKLKEEFGTASAIVSAFVASYRYWLSKQTFLWVMKLYTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NDQ3</accession>
    <name>A0A1C7NDQ3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">CDK5 and ABL1 enzyme substrate 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">CABLES1</name>
        <name evidence="4" type="ORF">A0J61_05261</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the cyclin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000280">
        <property type="protein sequence ID" value="OBZ86686.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NDQ3"/>
    <dbReference type="STRING" id="101091.A0A1C7NDQ3"/>
    <dbReference type="InParanoid" id="A0A1C7NDQ3"/>
    <dbReference type="OrthoDB" id="5353095at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051726">
        <property type="term" value="P:regulation of cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd20556">
        <property type="entry name" value="CYCLIN_CABLES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.10">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012388">
        <property type="entry name" value="CABLES1/2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013763">
        <property type="entry name" value="Cyclin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036915">
        <property type="entry name" value="Cyclin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006671">
        <property type="entry name" value="Cyclin_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22896">
        <property type="entry name" value="CDK5 AND ABL1 ENZYME SUBSTRATE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22896:SF0">
        <property type="entry name" value="CYCLIN N-TERMINAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00134">
        <property type="entry name" value="Cyclin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00385">
        <property type="entry name" value="CYCLIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47954">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0195">Cyclin</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cyclin-like" evidence="3">
        <location>
            <begin position="294"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="63"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="30"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="64"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="126"/>
            <end position="158"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU000383"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00385"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OBZ86686.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="424" mass="48378" checksum="6DBECDD3ED647946" modified="2016-11-30" version="1">MGTTKSRKSRRNNSRPTAFTFLSNIALGNENEKPPDDSIQRLSTYLSPNAELHYVEEEPAIGVSSLHSSDSSFSADEDHLQSPLPFDAHNRLNTSAAAPVITTHEYPKRGKYNAPKQHPSESSSDDVQHHKLTREDSERPIASEKIKKKSYHGERDHGQGTLSILSVFRYYTDKIRSSSSRKKSECFANRGYVQQQLESNDNHKHRRTQSYAHFLVATGSLVDEPQVEQNPSYDPFFLDDDTYGKYGLDPSSLGSLNNGARPSDLKREMNEQFRINHPEIPTEITLSKIRAIKLHLLEIGKQVDLEVSSVAHAYVFFEKLVIKNMVTKKNRKLIAACCLFLATKVNEAKGTWFRPLLDSIDNELGVDEEEIHEHEFAVFADLEFNLYVPRREFMPHFERIFQSLESKSIQAYLGHSSFYEAKKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NED7</accession>
    <name>A0A1C7NED7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">RING-type E3 ubiquitin transferase</fullName>
            <ecNumber evidence="4">2.3.2.27</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">doa10_2</name>
        <name evidence="14" type="ORF">A0J61_05034</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 16">
            <text>S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.</text>
            <dbReference type="EC" id="2.3.2.27"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.27" evidence="4"/>
    <dbReference type="EMBL" id="LUGH01000261">
        <property type="protein sequence ID" value="OBZ86916.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NED7"/>
    <dbReference type="STRING" id="101091.A0A1C7NED7"/>
    <dbReference type="InParanoid" id="A0A1C7NED7"/>
    <dbReference type="OrthoDB" id="264354at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036503">
        <property type="term" value="P:ERAD pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056521">
        <property type="entry name" value="MARCHF6-like_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13145:SF0">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE MARCHF6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13145">
        <property type="entry name" value="SSM4 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23113">
        <property type="entry name" value="MARCHF6_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="10" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="9 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="6 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="7" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="15"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="95"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="159"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="379"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="535"/>
            <end position="557"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="577"/>
            <end position="598"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="618"/>
            <end position="639"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="690"/>
            <end position="708"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="728"/>
            <end position="747"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="889"/>
            <end position="911"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="931"/>
            <end position="953"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="965"/>
            <end position="987"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="1007"/>
            <end position="1028"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="1035"/>
            <end position="1056"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="1068"/>
            <end position="1090"/>
        </location>
    </feature>
    <feature type="domain" description="E3 ubiquitin-protein ligase MARCHF6-like C-terminal" evidence="13">
        <location>
            <begin position="883"/>
            <end position="1090"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="256"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="320"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="10">
        <location>
            <begin position="200"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="264"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="323"/>
            <end position="333"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF23113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="OBZ86916.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="1113" mass="129074" checksum="5BC4DEA1C695C214" modified="2016-11-30" version="1">MKDEQEYVDLDQQLVNLYFILANVLEAYALFIMTVKLTTSIDIVCHDGYLIAIKIHLFQSYCELCDYRFVFTPIYRHDMPDRIPLHILLYQSISYVLNFALLCTRLTIAVFIWLFLIPVLTTWTWRFHFWTGSHISPDSKEDKKSLMNYEWSEVLSDCLQGLSITGTVVVLFVAAYLFRDWVIRNTASIQIEQHVQHPERDRGRQLITRLEALRQELEQRRNENEIEDITQYNNPYANNNSPYEMQNRRLFSLIDETDMPANPPSGTQSPFASWRDYQQGNSNSSLNDHTIDHANQRGLSRSTSMLRLQDPLDYFDQSSLAQTRSTSPTSEPSPLQPNNHQQEHPNDADQEPFSFSENMDSFLEAIGMRGSMLTLIKNAILMTLMINLCLWITVWIPYVIGRSIISIRFVSLMGISMHTIQSMFDSAISPILDKAIGPLYIQAEAIASLVLPNSFTIAFRNVLDNTIACICFIFKSIHIMLASDDSLLGGRLTQLTSDTTLLVSHDNWEWVRSNIYPIFVAIFRRWRQCAIGQSYVDRSVCTFTGYIFLISIGFWYLSKTHPANGSTSQAFRQQWVFLKVLFFIFLELVILPTIYGVLLDISTLPLFTDWSIKTRFHFVLLNPYSGIFLHWFVGTGLVLQSSIFVELIREVVRPGVLYFLPDPKDHRYRPIQDIVEQPTLLLIKRMCRIAVAYFMLILVGMGIVAIIVGKYGGIYPIVWKFGNPIMSIPIDLLIIQFLLPPIITYLVPREFSRKSATTWWHIVSRYLRLSSYMFGGRYPREEGTFVFKSWYGWLCYHLHLLPFGNVAFQKDKGQLVRVPSHDHVPLFLHRQKMIIPVDEVTLEPLDPAKPFVMISLHFMLNAIVHKYQSIRRYHRIVDWHSLRTKVKKVFVFVYMVFMFGLAVPLLLGITLDLYLLLPMKFFNKEEYVIELYLIVVSHFSFEFLYGFSIFFLSDDTYCVFEKKDWALGLAGMNVFHGIICISSLHISPTLREQFMQLNLSNFVNLDVKFVSKNILAPLVACILCILVLPSITSMAILYVFDFLIILISKCLKILAIHDPTIKLLIFRYTYPFHLGGALCLYAAYEFICLIRHSLHCMRDNVYLVGKRLHNIEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NEE6</accession>
    <name>A0A1C7NEE6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">ATP-dependent DNA helicase</fullName>
            <ecNumber evidence="1">5.6.2.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_04632</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="5.6.2.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the helicase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.6.2.3" evidence="1"/>
    <dbReference type="EMBL" id="LUGH01000230">
        <property type="protein sequence ID" value="OBZ87320.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NEE6"/>
    <dbReference type="STRING" id="101091.A0A1C7NEE6"/>
    <dbReference type="InParanoid" id="A0A1C7NEE6"/>
    <dbReference type="OrthoDB" id="5860629at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043139">
        <property type="term" value="F:5'-3' DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000723">
        <property type="term" value="P:telomere maintenance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010285">
        <property type="entry name" value="DNA_helicase_pif1-like_DEAD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10492">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10492:SF57">
        <property type="entry name" value="ATP-DEPENDENT DNA HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05970">
        <property type="entry name" value="PIF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0227">DNA damage</keyword>
    <keyword evidence="1" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="1" id="KW-0234">DNA repair</keyword>
    <keyword evidence="1" id="KW-0347">Helicase</keyword>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA helicase Pif1-like DEAD-box helicase" evidence="2">
        <location>
            <begin position="116"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU363044"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF05970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ87320.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="299" mass="33512" checksum="A05B347B3064F99D" modified="2016-11-30" version="1" fragment="single">CIIFVFCDPADPYQLWLDFKDKLSEDHRCQLLNDPVFDPTVDDIHETACNCALLDIEDILKRHYGTSLQWYDQFQLPSVDCRIDHISSPLSSLIQQQLQLNAAARQTDFSEDIANFNEDQRHVFDAIMHCVQRDGCTSTEFPRVFFVDRLGSTSKTYLFNTLLRAVRSTDEGFALAVASSGTAALLLDGGRTAHSLLKIPLETSSTTMCGIKPPSSEVELLKKTKLIIWDESSMIKKSTLETMDHTFKDIFGADNSALESIPFGGRLMVFGSDFRQVLPVVPKGSRADVVNACINRSYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NEM1</accession>
    <name>A0A1C7NEM1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Increased recombination centers protein 22</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">IRC22</name>
        <name evidence="12" type="ORF">A0J61_04398</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Is probably involved in a pathway contributing to genomic integrity.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Single-pass type I membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the IRC22 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000214">
        <property type="protein sequence ID" value="OBZ87555.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NEM1"/>
    <dbReference type="InParanoid" id="A0A1C7NEM1"/>
    <dbReference type="OrthoDB" id="1926781at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005595">
        <property type="entry name" value="TRAP_alpha"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12924:SF0">
        <property type="entry name" value="TRANSLOCON-ASSOCIATED PROTEIN SUBUNIT ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12924">
        <property type="entry name" value="TRANSLOCON-ASSOCIATED PROTEIN, ALPHA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03896">
        <property type="entry name" value="TRAP_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="6 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 11" id="KW-0732">Signal</keyword>
    <keyword evidence="2 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="11">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008889659" evidence="11">
        <location>
            <begin position="24"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="155"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="191"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="191"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="9">
        <location>
            <begin position="228"/>
            <end position="239"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004115"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00037565"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00038311"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="OBZ87555.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="239" mass="26257" checksum="51647A734614E904" modified="2016-11-30" version="1">MMLRGFSSLLTVGLFLVAGLVSAQTAESVATNVEVTAQFPDNPFGLIINGQRNKVVLDVVNKEKTPYTVFAVTGQVSKTDDYSKVLRNLTATRYGVSLESGASIQIPYNFYSEYVPGEHGLTIFVDLVSEQTVTRIVGYNGTMTVADPEGSWFDFQLLVLYGVLVAGAVGVGYIAREAFFPSAKKTKKVKKVEEVTERPAHRDEKGEMVLDQSWIPDSHLNLNSPKKTSPKAKKRSSRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NEQ1</accession>
    <name>A0A1C7NEQ1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">OST1A</name>
        <name evidence="11" type="ORF">A0J61_04430</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 10">Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3 10">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="10">Component of the oligosaccharyltransferase (OST) complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 10">Endoplasmic reticulum membrane</location>
            <topology evidence="2 10">Single-pass type I membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 10">Belongs to the OST1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000216">
        <property type="protein sequence ID" value="OBZ87528.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NEQ1"/>
    <dbReference type="FunCoup" id="A0A1C7NEQ1">
        <property type="interactions" value="759"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NEQ1"/>
    <dbReference type="InParanoid" id="A0A1C7NEQ1"/>
    <dbReference type="OrthoDB" id="310030at2759"/>
    <dbReference type="UniPathway" id="UPA00378"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008250">
        <property type="term" value="C:oligosaccharyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018279">
        <property type="term" value="P:protein N-linked glycosylation via asparagine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007676">
        <property type="entry name" value="Ribophorin_I"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21049:SF0">
        <property type="entry name" value="DOLICHYL-DIPHOSPHOOLIGOSACCHARIDE--PROTEIN GLYCOSYLTRANSFERASE SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21049">
        <property type="entry name" value="RIBOPHORIN I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04597">
        <property type="entry name" value="Ribophorin_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 10" id="KW-0732">Signal</keyword>
    <keyword evidence="11" id="KW-0808">Transferase</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="10">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008810993" description="Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1" evidence="10">
        <location>
            <begin position="21"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="11">
        <location>
            <position position="301"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002791"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004115"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00008905"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU361143"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="OBZ87528.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="301" mass="34192" checksum="46ECD4505CCA72F0" modified="2016-11-30" version="1" fragment="single">MRSVHFILFALSCLCSLVWAFPTQFENTKVVRVIEINTGIAREDIGVRAKNVDTKPATDYYFYLPHIVTQNAASISAFLRKQKTPLDVALQQADDDVNVYKVTLNEAIQPQQDLLLGIKVTYTHIVKPMPAKLPQVAKQHTVYAFNSYFLSPYLSKEVKTTLQTPTKGIVGHTGAENKSNAKDNKIVYGPYVDVPPRSFQLATAHFENTKPMITVTQLERDIQVSHWGNKLSVEEHYAVRNDGAQLDSDFNRVKYMMSQPIHEQTNVWKGLSYQLPQDAHDPYYRDEVGNVSTSRFRVEPT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NEX7</accession>
    <name>A0A1C7NEX7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Bis(5'-nucleosyl)-tetraphosphatase, symmetrical</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">apaH_1</name>
        <name evidence="3" type="ORF">A0J61_04287</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000206">
        <property type="protein sequence ID" value="OBZ87665.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NEX7"/>
    <dbReference type="STRING" id="101091.A0A1C7NEX7"/>
    <dbReference type="InParanoid" id="A0A1C7NEX7"/>
    <dbReference type="OrthoDB" id="10267127at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000298">
        <property type="term" value="F:endopolyphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016791">
        <property type="term" value="F:phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006798">
        <property type="term" value="P:polyphosphate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00144">
        <property type="entry name" value="MPP_PPP_family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050126">
        <property type="entry name" value="Ap4A_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42850">
        <property type="entry name" value="METALLOPHOSPHOESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42850:SF4">
        <property type="entry name" value="ZINC-DEPENDENT ENDOPOLYPHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="Metallo-dependent phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="34"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="domain" description="Calcineurin-like phosphoesterase" evidence="2">
        <location>
            <begin position="92"/>
            <end position="241"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ87665.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="343" mass="38307" checksum="3D32B7110A1DE58E" modified="2016-11-30" version="1">MAFFNSKDNASSIEYVDAFPVHQKTHKQKRLWRWIGMGVAAIVIIVVVIVVAVVVTDNKKKSNTSVPYPISPYSHMTKLVTNNDLSLQEKSRIFVLGDIHGCINELNKMVDKLNFNQTTDQLILAGDLTSKGPDSIGVIRRAKELGALCVRGNHDDKVVRFKTFQLQNGQDAMKPAEARMPEGDVPDRLKFKNYHEPIALNMTQEDYDYLSSCPVILHLPFLNNTVIVHGGLDPHIQSLQDQVPYLVMNMRDIDGNNQPNIEVGTGTQWATVYNSDQANSTTDDMMVFYGHDSKRGLNIKQTTFGLDSGCVYGNQLSAINIRTKELTQINCLTYAKKGGDSDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NF89</accession>
    <name>A0A1C7NF89_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Guanine nucleotide-binding protein alpha-3 subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">GPA3</name>
        <name evidence="11" type="ORF">A0J61_04213</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000200">
        <property type="protein sequence ID" value="OBZ87747.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NF89"/>
    <dbReference type="FunCoup" id="A0A1C7NF89">
        <property type="interactions" value="171"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NF89"/>
    <dbReference type="InParanoid" id="A0A1C7NF89"/>
    <dbReference type="OrthoDB" id="5817230at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005834">
        <property type="term" value="C:heterotrimeric G-protein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001664">
        <property type="term" value="F:G protein-coupled receptor binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031683">
        <property type="term" value="F:G-protein beta/gamma-subunit complex binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007189">
        <property type="term" value="P:adenylate cyclase-activating G protein-coupled receptor signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032502">
        <property type="term" value="P:developmental process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010255">
        <property type="term" value="P:glucose mediated signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd00066">
        <property type="entry name" value="G-alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.400.10:FF:000007">
        <property type="entry name" value="Guanine nucleotide-binding protein subunit alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000181">
        <property type="entry name" value="Guanine nucleotide-binding protein subunit alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000692">
        <property type="entry name" value="Guanine nucleotide-binding protein subunit alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.400.10">
        <property type="entry name" value="GI Alpha 1, domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002975">
        <property type="entry name" value="Fungi_Gprotein_alpha"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001019">
        <property type="entry name" value="Gprotein_alpha_su"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011025">
        <property type="entry name" value="GproteinA_insert"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10218">
        <property type="entry name" value="GTP-BINDING PROTEIN ALPHA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10218:SF369">
        <property type="entry name" value="GUANINE NUCLEOTIDE-BINDING PROTEIN ALPHA-2 SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00503">
        <property type="entry name" value="G-alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00318">
        <property type="entry name" value="GPROTEINA"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01241">
        <property type="entry name" value="GPROTEINAFNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00275">
        <property type="entry name" value="G_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47895">
        <property type="entry name" value="Transducin (alpha subunit), insertion domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51882">
        <property type="entry name" value="G_ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 9" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="8" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="4 10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="2 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1" id="KW-0519">Myristate</keyword>
    <keyword evidence="3 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-0564">Palmitate</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0807">Transducer</keyword>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="43"/>
            <end position="48"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="47"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="149"/>
            <end position="150"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="180"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="199"/>
            <end position="203"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="268"/>
            <end position="271"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="323"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR601019-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR601019-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="OBZ87747.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="351" mass="40739" checksum="C9223A7F65F8F348" modified="2016-11-30" version="1">MGACLSSEERDEKLNSYKIDKTIEEDDKNRKREFKMLLLGSGESGKSTIFKQMKILHQNGYSTEELKNWRITVFRNIIQSAQTIANALRQYDYPIQSEKLGYEIQRIIDYRLTEDTLDPLFVDAVLSVWPTAIVTSMLETHASDFYLMDSAAYFFENLGRIAQSDYIPTTQDVVHARSKTTGIVETRFSINKITIHMFDVGGQRSERKKWIHCFESVDSIVFCVSLSEYDQVLLEESRQNRMMESLVLFESVINSRWFSSTTIILFLNKVDIFKEKIKKVPLEKYFPDYGGGKKVNLAAKYILWRFNQMNRAKLKIYPHLTQATSTTNMDHTFQGIRETLIQSQLNDSGIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NFB9</accession>
    <name>A0A1C7NFB9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Heat shock protein hsp88</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">hsp88</name>
        <name evidence="7" type="ORF">A0J61_05912</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000334">
        <property type="protein sequence ID" value="OBZ86044.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NFB9"/>
    <dbReference type="FunCoup" id="A0A1C7NFB9">
        <property type="interactions" value="853"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NFB9"/>
    <dbReference type="InParanoid" id="A0A1C7NFB9"/>
    <dbReference type="OrthoDB" id="434160at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd24094">
        <property type="entry name" value="ASKHA_NBD_HSP70_ScSse"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1270.10:FF:000002">
        <property type="entry name" value="Heat shock 70 kDa protein 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.30.30:FF:000002">
        <property type="entry name" value="Heat shock 70 kDa protein 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.40:FF:000171">
        <property type="entry name" value="Heat shock 70 kDa protein 4"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.640.10:FF:000004">
        <property type="entry name" value="Heat shock 70 kDa protein 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.34.10:FF:000011">
        <property type="entry name" value="Heat shock protein hsp88"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.640.10">
        <property type="entry name" value="Actin, Chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.34.10">
        <property type="entry name" value="Substrate Binding Domain Of DNAk, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018181">
        <property type="entry name" value="Heat_shock_70_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029048">
        <property type="entry name" value="HSP70_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029047">
        <property type="entry name" value="HSP70_peptide-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013126">
        <property type="entry name" value="Hsp_70_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45639:SF4">
        <property type="entry name" value="HSC70CB, ISOFORM G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45639">
        <property type="entry name" value="HSC70CB, ISOFORM G-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00012">
        <property type="entry name" value="HSP70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00301">
        <property type="entry name" value="HEATSHOCK70"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100934">
        <property type="entry name" value="Heat shock protein 70kD (HSP70), C-terminal subdomain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100920">
        <property type="entry name" value="Heat shock protein 70kD (HSP70), peptide-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01036">
        <property type="entry name" value="HSP70_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7" id="KW-0346">Stress response</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="719"/>
            <end position="765"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="754"/>
            <end position="765"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OBZ86044.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="765" mass="85662" checksum="82EFE9F0C2BE5B50" modified="2016-11-30" version="1">MSVVGIDLGNLQTVIAVARNRGIDVICNEVSNRATPTIVSFGPKQRFLGEAAKTQEISNAKNTVVSLKRLAGRKNDDPEVVEIENKYIIAELAEVAAQAGVKVNYLGEEQIFSNVQLLAMYLHKIKDITAAEIKGPVSDCVITVPVWFTEVQRRAVLTASEIVGLNCLRLVNDLTAAALGYGITKLDLPEDKPRNVAFVDIGHSSYSVQLVSFLKGQLTVRGTAFDEHFGGREFDAVIVDKLAEQFKEKYKIDVFSNKKALLRLRVAAERCKKILSANPQAPVNIESIMEDRDVSAMVSREEFEEWASHLFTRTEGVLTKALENAAMKVEEIDSVEIVGGTTRIPAIKATISKFFGKDISTTLNQDEAMARGAALQCAMLSPVFKVREFRINDVVTHPIKLTWEATPEEEETEIVVFDNNNSLPSTKILTFFRREPFTLEALYAKPEALPRGINPWLGRFDIKDVAPVNNEPAQIKVKVRINIHGIMTVESAYTVEEKMVEEEVKNKDGEKEVKKVKKLVKTGDLPVVAFHTGLAKDLINEYTEKETQMYANDKLIAATEAAKNSLEEYGYEMRDKIVGPLSDYIDASIKDKFAQDLSDVVDWIYDEGYDAPKSVYVEKLEALKKIGNPVVERYREAEERPHAERSLRETIQRLTTEAMSSDDKYSHIPAHEKQDIVERCERAGRWMDEQNAKQAALPKNQTPVLFARDIKKEEEAITYFANPILNKPKPAPKPEETNTESSTADADTPMDDASDNKKKEDMDID</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NG65</accession>
    <name>A0A1C7NG65_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Malic enzyme</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">malA_1</name>
        <name evidence="11" type="ORF">A0J61_04222</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <cofactor evidence="7">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <text evidence="7">Divalent metal cations. Prefers magnesium or manganese.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the malic enzymes family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000201">
        <property type="protein sequence ID" value="OBZ87729.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NG65"/>
    <dbReference type="STRING" id="101091.A0A1C7NG65"/>
    <dbReference type="InParanoid" id="A0A1C7NG65"/>
    <dbReference type="OrthoDB" id="5365701at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004471">
        <property type="term" value="F:malate dehydrogenase (decarboxylating) (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006108">
        <property type="term" value="P:malate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05312">
        <property type="entry name" value="NAD_bind_1_malic_enz"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000182">
        <property type="entry name" value="NAD-dependent malic enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10380">
        <property type="entry name" value="Malic enzyme, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046346">
        <property type="entry name" value="Aminoacid_DH-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015884">
        <property type="entry name" value="Malic_enzyme_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012301">
        <property type="entry name" value="Malic_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037062">
        <property type="entry name" value="Malic_N_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012302">
        <property type="entry name" value="Malic_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001891">
        <property type="entry name" value="Malic_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF010052">
        <property type="entry name" value="PRK13529.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23406">
        <property type="entry name" value="MALIC ENZYME-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23406:SF32">
        <property type="entry name" value="NADP-DEPENDENT MALIC ENZYME"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00390">
        <property type="entry name" value="malic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03949">
        <property type="entry name" value="Malic_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000106">
        <property type="entry name" value="ME"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00072">
        <property type="entry name" value="MALOXRDTASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM01274">
        <property type="entry name" value="malic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00919">
        <property type="entry name" value="Malic_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53223">
        <property type="entry name" value="Aminoacid dehydrogenase-like, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00331">
        <property type="entry name" value="MALIC_ENZYMES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Malic enzyme N-terminal" evidence="10">
        <location>
            <begin position="3"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="domain" description="Malic enzyme NAD-binding" evidence="9">
        <location>
            <begin position="194"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="5">
        <location>
            <position position="18"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="5">
        <location>
            <position position="98"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="80"/>
        </location>
        <ligand>
            <name>(S)-malate</name>
            <dbReference type="ChEBI" id="CHEBI:15589"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="169"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="170"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="193"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="341"/>
        </location>
        <ligand>
            <name>(S)-malate</name>
            <dbReference type="ChEBI" id="CHEBI:15589"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="387"/>
        </location>
        <ligand>
            <name>(S)-malate</name>
            <dbReference type="ChEBI" id="CHEBI:15589"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008785"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR000106-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR000106-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR000106-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003426"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM01274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="OBZ87729.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="489" mass="54090" checksum="2D49401C13C5DDDF" modified="2016-11-30" version="1">MSLFVVTTKKKELAPVVYTPTVGEACLKYSEIYPFLNPPGAPDGLCITLDDLSRLDDILESYKLRSGQTPDITVMTDGSRILGLGDLGINGMPICMGKLQLYVASAGIHPHRTLPVTLDFGTNNEAYLTDEHYMGVRKKRPDDSTFYEAVNQVLFALRRVFPDIVVQFEDFSSAHAFGLLKRHRSQLACFNDDIQGTGVVVLAGLINAFRKVARTTNLRIQDHRIVFHGAGSAAIGVARQIQRYLETEHGVSEEEAKRIFYFCDSKGLITLDRGDTLAEHKVDYARKDNQGQQYRTLEEIVSYARPTALLGFSSVAHAFTSKVLSLMHQLNERPIIFPLSNPANKAECSFKEAMKATDNKAIFASGTAFPAYIDPETKKKYIPGQGNNMFVFPGLGLGSILSKTTSVSDDMLNSAAKALANSLTPEEVERGLIYPSLARIREVSSVVATAVIEQTMNEKLAKIDQIPEKQIKSFVESHMWSPEVEPSQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-06-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NG93</accession>
    <name>A0A1C7NG93_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_03896</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000178">
        <property type="protein sequence ID" value="OBZ88055.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NG93"/>
    <dbReference type="InParanoid" id="A0A1C7NG93"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ88055.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="114" mass="13242" checksum="2C4BBE608A0E7AF4" modified="2016-11-30" version="1">MFHRSSQSILSFHNQALIHIDVEIHGKNVINDKLSHLFPDEQDHMFLDKVEKLLLPHLHSRKKESKSGKKMLTSLRSIHQDRIANFRQCFCATTVSSKPLKIEEESEQLVRITA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NHB1</accession>
    <name>A0A1C7NHB1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_03536</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000154">
        <property type="protein sequence ID" value="OBZ88415.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NHB1"/>
    <dbReference type="InParanoid" id="A0A1C7NHB1"/>
    <dbReference type="OrthoDB" id="2285387at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="85"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="85"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="118"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ88415.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="169" mass="19889" checksum="32B94ADB0823EEB5" modified="2016-11-30" version="1">MSEQVIYPKLALEFPCLACPYVANNPPQILEHYQRCHDFKVDIHALPLQTTTQYACPLCLSCMEPSPNALYTHYQNDHDLTMLIEGDKVKEDVSKRRQRHAEEREKEKEMPRVMKQEETEDEEEEERDELEEPEEPEEEESSEKKETIQKINELIEMFGSFVKTMKPAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NHC2</accession>
    <name>A0A1C7NHC2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Nitrogen regulatory protein nrfA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">nrfA</name>
        <name evidence="9" type="ORF">A0J61_03511</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000153">
        <property type="protein sequence ID" value="OBZ88435.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NHC2"/>
    <dbReference type="STRING" id="101091.A0A1C7NHC2"/>
    <dbReference type="InParanoid" id="A0A1C7NHC2"/>
    <dbReference type="OrthoDB" id="515401at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000122">
        <property type="term" value="P:negative regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00202">
        <property type="entry name" value="ZnF_GATA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.50.10:FF:000007">
        <property type="entry name" value="Nitrogen regulatory AreA, N-terminal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.50.10">
        <property type="entry name" value="Erythroid Transcription Factor GATA-1, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039355">
        <property type="entry name" value="Transcription_factor_GATA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000679">
        <property type="entry name" value="Znf_GATA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013088">
        <property type="entry name" value="Znf_NHR/GATA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10071:SF281">
        <property type="entry name" value="BOX A-BINDING FACTOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10071">
        <property type="entry name" value="TRANSCRIPTION FACTOR GATA FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00320">
        <property type="entry name" value="GATA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00619">
        <property type="entry name" value="GATAZNFINGER"/>
    </dbReference>
    <dbReference type="SMART" id="SM00401">
        <property type="entry name" value="ZnF_GATA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57716">
        <property type="entry name" value="Glucocorticoid receptor-like (DNA-binding domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00344">
        <property type="entry name" value="GATA_ZN_FINGER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50114">
        <property type="entry name" value="GATA_ZN_FINGER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 6" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="GATA-type" evidence="8">
        <location>
            <begin position="245"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="56"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="104"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="182"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="352"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="470"/>
            <end position="519"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="56"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="78"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="118"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="182"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="233"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="497"/>
            <end position="519"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00094"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50114"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OBZ88435.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="519" mass="57020" checksum="3BF2554D3A9C158D" modified="2016-11-30" version="1" fragment="single">PVSRGTLDSSDNKDHLNQCSLDAETNQMDEDDIQRLSQSLPSHSYFVQPTQHDYMNDSSDMFPSFHTSSPDRSGANTPSLLQHYHPSSPPLSSSANSFYFGIHPNQHSLPGSPMDPLHTTSQLNTGASTPTGINPFMAHPGSLSFEEMLHVYYQQEQNSHELPMTEHHPQVLMPLQPAYLSSSTTAESASSSPHSIASPHSLSSSDDHSHDEDEDDMTSRQANRGNKHKRNRTSVSRQSNKASNNANKTQCHNCQTTTTPLWRRDPQGNPLCNACGLFLKLHGAVRPLSLKTDIIKKRNRSTNNTPMTQSKSSVQVKAIKKQLSYPLEPIEQKQDGFTSRPSLDRRNTVHIAPHHPYSAGSNNRSMIPMKSTSKRQRRTSDIVPIATHSSPMKPSASYAESSSYGAPSIPIPFLHSSETLHSSMKVPTPTDNATNAAVTAILESVGIHLNSLPVELLPLVASAANYHAANKQRMKEQKPDNAISQPSFHPSPPSSMPTPVTLNPSLQQQSFSFNNSLDN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NHD8</accession>
    <name>A0A1C7NHD8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_03529</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000153">
        <property type="protein sequence ID" value="OBZ88428.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NHD8"/>
    <dbReference type="InParanoid" id="A0A1C7NHD8"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="43"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ88428.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="86" mass="9515" checksum="80CE8D702F1673A4" modified="2016-11-30" version="1">MIEDQRSDKEGSIEQIIPASEPSLKSNHIDRKGLHCFSLGLKIFAIIAIIGIVILCALLPNYIQNKKALENESTDPTNARLPESKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NHT3</accession>
    <name>A0A1C7NHT3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">A0J61_03349</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion inner membrane</location>
            <topology evidence="2">Single-pass membrane protein</topology>
            <orientation evidence="2">Matrix side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the complex I NDUFA1 subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000142">
        <property type="protein sequence ID" value="OBZ88595.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NHT3"/>
    <dbReference type="STRING" id="101091.A0A1C7NHT3"/>
    <dbReference type="InParanoid" id="A0A1C7NHT3"/>
    <dbReference type="OrthoDB" id="1920692at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017384">
        <property type="entry name" value="NADH_Ub_cplx-1_asu_su-1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17098:SF2">
        <property type="entry name" value="NADH DEHYDROGENASE [UBIQUINONE] 1 ALPHA SUBCOMPLEX SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17098">
        <property type="entry name" value="NADH-UBIQUINONE OXIDOREDUCTASE MWFE SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15879">
        <property type="entry name" value="MWFE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0249">Electron transport</keyword>
    <keyword evidence="12 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="8" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0679">Respiratory chain</keyword>
    <keyword evidence="7 13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10 13" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004298"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00016392"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022660"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="OBZ88595.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="87" mass="10012" checksum="A4B9D5CC8686976D" modified="2016-11-30" version="1">MPVPFEALIPFGLIAGMFTITATGLNVVRYYSNDRKPGRYGLDIWERQMMERDRRLTGSLRGQSDNPTAPPAFATNSIWYLEKHRNH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NHU2</accession>
    <name>A0A1C7NHU2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">PH and SEC7 domain-containing protein C11E3.11c</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">A0J61_03341</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000142">
        <property type="protein sequence ID" value="OBZ88605.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NHU2"/>
    <dbReference type="FunCoup" id="A0A1C7NHU2">
        <property type="interactions" value="30"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NHU2"/>
    <dbReference type="InParanoid" id="A0A1C7NHU2"/>
    <dbReference type="OrthoDB" id="2157641at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005085">
        <property type="term" value="F:guanyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032012">
        <property type="term" value="P:regulation of ARF protein signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00171">
        <property type="entry name" value="Sec7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1000.11">
        <property type="entry name" value="Arf Nucleotide-binding Site Opener,domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041681">
        <property type="entry name" value="PH_9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023394">
        <property type="entry name" value="Sec7_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000904">
        <property type="entry name" value="Sec7_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035999">
        <property type="entry name" value="Sec7_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10663">
        <property type="entry name" value="GUANYL-NUCLEOTIDE EXCHANGE FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10663:SF373">
        <property type="entry name" value="PH AND SEC7 DOMAIN-CONTAINING PROTEIN C11E3.11C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15410">
        <property type="entry name" value="PH_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01369">
        <property type="entry name" value="Sec7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00222">
        <property type="entry name" value="Sec7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48425">
        <property type="entry name" value="Sec7 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50190">
        <property type="entry name" value="SEC7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SEC7" evidence="3">
        <location>
            <begin position="500"/>
            <end position="695"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="58"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="106"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="174"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="327"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="740"/>
            <end position="811"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1095"/>
            <end position="1122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="58"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="73"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="179"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="192"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="334"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="740"/>
            <end position="751"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="767"/>
            <end position="782"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="791"/>
            <end position="811"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OBZ88605.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="1155" mass="130733" checksum="E2CCEDBADC359205" modified="2016-11-30" version="1">MLPNSRIIPPNTEQTNARRRSNSVLNDKKGLISRLLTKEQPSLQNQQRSIHDYISDSQREDHTYHSSFEHSKPISSSTKTNSTGFGKLFKKRGKVLDDDLVLNTEEDQPHIRPIQHQQSKSHNKIPLAPPPEYPKAKTISQPDQHQFLTNLPVHYLTKRPTHDPPPIQLPPIPTPTIPSSPIDIGSTPLEADSTSSLRKSSGSYSIYSTFGGDESIYSADSLEQPRYSAQSVGGESVNSFTTVVSQQHSSEEIDDTDSATTTIITATSSDDEDDFVDATGFSQEDIEREQRMLEEEEVNNGSLTKRLSGGHYGSAGGLVASIQKNENRLSKSPPGSPVPALPIPPVPPIPEQHQPHHRRKSKRSTTPDDDLAESMLNWKRHSGNSKRWSARSSVQSKTVFSKDEKRASTITVIDLRSTLPSEPEELSTMDKMALRKQAEEALSGTKAVSTSCLPLASKDDHLPSTLSFNSVPRANSLQFTTDFSKTLDDVWKTSEDNLHLFNDPRSKTLETNIKVHVSEQEGPTEELEKAKQAACLLWNEDETIVAREKMAEWLGKGKPFQTAVLYEYMQLFVFHEMRLDSAFRKLCSKLYFKAEAQQIDRILECFANRYWECNPDNLFGSADTVYAVVYSLLLLNTDLHVAQGNHARMTRSEFIRNTMSTIREQRDEHNSPEYRNWEAEVEFNLKEMYTSVKHYQILQPLGKDSHLTKRGSILRGRRVIGIKRSVHSIIRKSARESILMTETQDQDTIVVSPTTSSSPSLGPPPRNSMSSSYNRSTTPSSSIKSPRRDSYSSTNSSVASLGSPHSPQPTVQYINTHATSLFSSRPPYFKEGIVVRKHLLETANQKAKHREWKECFVEVGHTGELRMYALQDGGSEGHSNRSLFRHSTTIQDLKHNNKWASSAQLIGKVALNHTLSNPLPPPGYNRQRPHVFALQQSDGGVYLFQVASAEQAQEWVMTCNYWAARESKQNVDTGVGNMEYGWGDCLGDVVMDLDAMHQGYDQTFHLHSALQDPDSIMIQDWIPPTPTMVSSQLDEEKQFESLQQHLVYLNNEINYHRDIKSKVFIKFPVKCHNYNRVLSNWETRSKYLLHDIIKYQNYCDALEKSLQTRQELKREKEEEGKKTVVYDSILPNSKLEYQSSAVDLFKEINQELRFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NIA9</accession>
    <name>A0A1C7NIA9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Eukaryotic peptide chain release factor subunit 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">etf1</name>
        <name evidence="6" type="ORF">A0J61_03090</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the eukaryotic release factor 1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000127">
        <property type="protein sequence ID" value="OBZ88857.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NIA9"/>
    <dbReference type="FunCoup" id="A0A1C7NIA9">
        <property type="interactions" value="952"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NIA9"/>
    <dbReference type="InParanoid" id="A0A1C7NIA9"/>
    <dbReference type="OrthoDB" id="10254527at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010494">
        <property type="term" value="C:cytoplasmic stress granule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018444">
        <property type="term" value="C:translation release factor complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030695">
        <property type="term" value="F:GTPase regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004045">
        <property type="term" value="F:peptidyl-tRNA hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016149">
        <property type="term" value="F:translation release factor activity, codon specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002184">
        <property type="term" value="P:cytoplasmic translational termination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006353">
        <property type="term" value="P:DNA-templated transcription termination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009302">
        <property type="term" value="P:sno(s)RNA transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.60:FF:000001">
        <property type="entry name" value="Eukaryotic peptide chain release factor subunit 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.960.10:FF:000001">
        <property type="entry name" value="Eukaryotic peptide chain release factor subunit 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1330.30:FF:000006">
        <property type="entry name" value="Peptide chain release factor subunit 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.960.10">
        <property type="entry name" value="eRF1 domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.60">
        <property type="entry name" value="eRF1 domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042226">
        <property type="entry name" value="eFR1_2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024049">
        <property type="entry name" value="eRF1_1_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005141">
        <property type="entry name" value="eRF1_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005142">
        <property type="entry name" value="eRF1_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005140">
        <property type="entry name" value="eRF1_Pelota-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004403">
        <property type="entry name" value="Peptide_chain-rel_eRF1/aRF1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029064">
        <property type="entry name" value="Ribosomal_eL30-like_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR03676">
        <property type="entry name" value="aRF1_eRF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10113">
        <property type="entry name" value="PEPTIDE CHAIN RELEASE FACTOR SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03463">
        <property type="entry name" value="eRF1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03464">
        <property type="entry name" value="eRF1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03465">
        <property type="entry name" value="eRF1_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01194">
        <property type="entry name" value="eRF1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55315">
        <property type="entry name" value="L30e-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55481">
        <property type="entry name" value="N-terminal domain of eukaryotic peptide chain release factor subunit 1, ERF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53137">
        <property type="entry name" value="Translational machinery components"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="eRF1/Pelota-like N-terminal" evidence="5">
        <location>
            <begin position="7"/>
            <end position="143"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM01194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OBZ88857.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="443" mass="49628" checksum="F361A01CE8EBD9B8" modified="2016-11-30" version="1">MSSAQPADNTDENVEIWKMKKLIKNLEMARGNGTSMISLVIPPKDQISRVVKMLADEYGTASNIKSRVNRLSVLSAITSTQQRLKLYTRVPDNGLVVYCGTIITDEGKEKKVNIDFEPHKPINTSLYLCDNKFHVEPLAELLDNDAKFGFIVMDGNGTLFGTVSGNVRDVIHKLSVDLPKKHGRGGQSALRFSRLREEKRHNYVRKIAELAVQLFITNDKVNCAGLVLAGSADFKTELSQSDLFDPRLRAKIVKIVDVSYGGENGFNQAIELSAEALSNVKFIQEKRLINDYFSEISQDTGKYCFGIDDTLKALEMGAVETLIVWENLAANRYTLRDASGTEVIVYPNPEEEKTKSFMADTSADATANSEMEVIEVMPLLEWFTLKYKDFGAALEIITDRSQEGSQFVRGFGGIGGILRYRVNFEQLNYDSDEFISDDDEEYI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NID5</accession>
    <name>A0A1C7NID5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Tyrosine-protein phosphatase non-receptor type 20</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">Ptpn20</name>
        <name evidence="4" type="ORF">A0J61_03078</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein-tyrosine phosphatase family. Non-receptor class subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000126">
        <property type="protein sequence ID" value="OBZ88877.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NID5"/>
    <dbReference type="STRING" id="101091.A0A1C7NID5"/>
    <dbReference type="InParanoid" id="A0A1C7NID5"/>
    <dbReference type="OrthoDB" id="6058203at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004725">
        <property type="term" value="F:protein tyrosine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd18533">
        <property type="entry name" value="PTP_fungal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.190.10">
        <property type="entry name" value="Protein tyrosine phosphatase superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029021">
        <property type="entry name" value="Prot-tyrosine_phosphatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050348">
        <property type="entry name" value="Protein-Tyr_Phosphatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000242">
        <property type="entry name" value="PTP_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016130">
        <property type="entry name" value="Tyr_Pase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003595">
        <property type="entry name" value="Tyr_Pase_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000387">
        <property type="entry name" value="Tyr_Pase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19134:SF561">
        <property type="entry name" value="PROTEIN TYROSINE PHOSPHATASE 36E, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19134">
        <property type="entry name" value="RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00102">
        <property type="entry name" value="Y_phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00700">
        <property type="entry name" value="PRTYPHPHTASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00194">
        <property type="entry name" value="PTPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00404">
        <property type="entry name" value="PTPc_motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52799">
        <property type="entry name" value="(Phosphotyrosine protein) phosphatases II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00383">
        <property type="entry name" value="TYR_PHOSPHATASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50056">
        <property type="entry name" value="TYR_PHOSPHATASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50055">
        <property type="entry name" value="TYR_PHOSPHATASE_PTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0675">Receptor</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tyrosine-protein phosphatase" evidence="2">
        <location>
            <begin position="41"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="domain" description="Tyrosine specific protein phosphatases" evidence="3">
        <location>
            <begin position="231"/>
            <end position="307"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OBZ88877.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="322" mass="37250" checksum="BC54F4EA6C9D546D" modified="2016-11-30" version="1">MGWRTIQKAFRSMSTSEVVNKPTIEILKNLLNDQAKFQLYAHHRFAQVNNLEEERYQLPDYQHTEAQKNNKLNRYSDIVPYDNNCIKLTDKRLGPTQDDYINASWIVAPHDIPRVYIATQGPMPHTIVDFWRLVVEQQVPVIVCLTAQMDGKVEKCARYWPVGDQALEWTHHDVTIKVMNVAEESENEGAACIQRTIQVSFYHQDQLVEETKVTQLQFLGWPDHGVPKETDKVIGLIQLTRQLQETNKPVLVHCSAGCGRTGTFCVIDSAEVLVRNNPQFRMDPVFYLTDEFRKQRTTMVQAEAQYGFCYRALLDFLDLESK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NIG7</accession>
    <name>A0A1C7NIG7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_03371</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000143">
        <property type="protein sequence ID" value="OBZ88589.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NIG7"/>
    <dbReference type="InParanoid" id="A0A1C7NIG7"/>
    <dbReference type="OrthoDB" id="2226573at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ88589.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="60" mass="6750" checksum="2B37292B048D0E99" modified="2016-11-30" version="1">MNNIIDISDDTEGSHLAELDGESQRRLADLLSSSPTEQEIDQYNCHHLESIIKKIQQGGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NIS0</accession>
    <name>A0A1C7NIS0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="10">N-chimaerin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">Chn1_1</name>
        <name evidence="10" type="ORF">A0J61_03513</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000153">
        <property type="protein sequence ID" value="OBZ88436.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NIS0"/>
    <dbReference type="InParanoid" id="A0A1C7NIS0"/>
    <dbReference type="OrthoDB" id="74314at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005778">
        <property type="term" value="C:peroxisomal membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007031">
        <property type="term" value="P:peroxisome organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd00029">
        <property type="entry name" value="C1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.60.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046349">
        <property type="entry name" value="C1-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052646">
        <property type="entry name" value="Peroxisomal_PEX28-32"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002219">
        <property type="entry name" value="PKC_DAG/PE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010482">
        <property type="entry name" value="TECPR1-like_DysF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31679">
        <property type="entry name" value="PEROXISOMAL MEMBRANE PROTEIN PEX30-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31679:SF2">
        <property type="entry name" value="PEROXISOMAL MEMBRANE PROTEIN PEX30-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00130">
        <property type="entry name" value="C1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06398">
        <property type="entry name" value="Pex24p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00109">
        <property type="entry name" value="C1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57889">
        <property type="entry name" value="Cysteine-rich domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00479">
        <property type="entry name" value="ZF_DAG_PE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50081">
        <property type="entry name" value="ZF_DAG_PE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="203"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="289"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="domain" description="Phorbol-ester/DAG-type" evidence="9">
        <location>
            <begin position="8"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="92"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="97"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="115"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="130"/>
            <end position="153"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004308"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50081"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OBZ88436.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="496" mass="56801" checksum="1C918B0E64AD9AB4" modified="2016-11-30" version="1">MPSTAIKYHVFKEKNFQGLVYCDYCGKLLWGSGRQGAQCTECGYNCHIACSDMVIQCRPARRYSPDSLSITDSEAESVSKYSVHSVAXRHSLERHNSNTLDDSMSTGSSSRKHSGRIDLANRKLDEPLKSPTSGTQTINNSHEPYSRSSKHSLNTSYRKSLQHQLQSLKLSSTDTMSPHATAKAFTRLVARWKNKIHSMLVCLLWISICIDIRVGLIIPPLLIGLLYRKAGIRQQNASLVLFPRYDENTTEYYTNLGHMQYAFTFLIRLYDNMVYHLQHITLDGTTYRILLVSSLFVSLAFAYFGKWLIMMIGLMILCNRTWIGSLIEALLLFCVEVVQTIADLGQRLMTNKDKAIERRPMEVSVYENQRWWASTGYTSQMLRSERSAWSNITGLEPLPSKDDMPPPAHYIWETGSEWQLDTTGPWTDDVLNIVNLIECDENGWVYSDHRWQNPQGNPDLVNNRSNEANTKALTRRRRWFRKASPVILAAYNKKTM</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NIT6</accession>
    <name>A0A1C7NIT6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_03046</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000124">
        <property type="protein sequence ID" value="OBZ88918.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NIT6"/>
    <dbReference type="STRING" id="101091.A0A1C7NIT6"/>
    <dbReference type="InParanoid" id="A0A1C7NIT6"/>
    <dbReference type="OrthoDB" id="2276331at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ88918.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="131" mass="15809" checksum="5A75C508A47E0A8D" modified="2016-11-30" version="1">MVVEQTDEIQRFIDARYVSASEACWRLFSFSLHDEFPKHQRLTIHLPGEEPVYFDEDDQAEDVLNRPTKDTTLTAWFKANVENEYARQYLYIEFPEKYVWHKKDSEWKIRKRNLDTTIGQIYSISPRETEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NJ32</accession>
    <name>A0A1C7NJ32_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">glucan 1,3-beta-glucosidase</fullName>
            <ecNumber evidence="9">3.2.1.58</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">exgA_1</name>
        <name evidence="12" type="ORF">A0J61_03442</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>Successive hydrolysis of beta-D-glucose units from the non-reducing ends of (1-&gt;3)-beta-D-glucans, releasing alpha-glucose.</text>
            <dbReference type="EC" id="3.2.1.58"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the glycosyl hydrolase 5 (cellulase A) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.58" evidence="9"/>
    <dbReference type="EMBL" id="LUGH01000148">
        <property type="protein sequence ID" value="OBZ88506.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NJ32"/>
    <dbReference type="STRING" id="101091.A0A1C7NJ32"/>
    <dbReference type="InParanoid" id="A0A1C7NJ32"/>
    <dbReference type="OrthoDB" id="1887033at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009986">
        <property type="term" value="C:cell surface"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004338">
        <property type="term" value="F:glucan exo-1,3-beta-glucosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009251">
        <property type="term" value="P:glucan catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001547">
        <property type="entry name" value="Glyco_hydro_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050386">
        <property type="entry name" value="Glycosyl_hydrolase_5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31297:SF1">
        <property type="entry name" value="GLUCAN 1,3-BETA-GLUCOSIDASE I_II-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31297">
        <property type="entry name" value="GLUCAN ENDO-1,6-BETA-GLUCOSIDASE B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00150">
        <property type="entry name" value="Cellulase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="6 10" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="5 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0964">Secreted</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="domain" description="Glycoside hydrolase family 5" evidence="11">
        <location>
            <begin position="67"/>
            <end position="330"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00036824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00038929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU361153"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="OBZ88506.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="360" mass="41068" checksum="644B4B0B6003BA7A" modified="2016-11-30" version="1">MNLLSFIGAQHYETPFDYRTASAWGANLGNWLILEKWMDSTIFDSYAPGAIDEWTFSEQASSPAEALKEHWESWITEDDFVLLSNTHTNHVRIPVGYWAFIPPDRGEPYIYSDQKAQLERILGYCKAYGMYAIIDLHGLPGSQNGNDHSGRKGHIGFFTMYNIRRGIKVVKAIINWMNSLSSDLKSTIAAIEVANEPDVADDKLYLLKYYYLKTFKLIRTSPFKVNMMFHDGFKGLKTWRHFLPSKANAVIDLHPYYAFPPVKETNAIIDGIRSCKKPAKDFHLPVFYGEWSLASGVSSNTLWLKTMMDSQISVFKATGAGGTFWTIKNKINSNVWSFEHLVREGVVTPETFKYHPKAQC</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NJU0</accession>
    <name>A0A1C7NJU0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 3">Pre-mRNA-processing protein 45</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">prp45</name>
        <name evidence="6" type="ORF">A0J61_02895</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Involved in pre-mRNA splicing.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Associated with the spliceosome.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the SNW family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000116">
        <property type="protein sequence ID" value="OBZ89059.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NJU0"/>
    <dbReference type="FunCoup" id="A0A1C7NJU0">
        <property type="interactions" value="873"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NJU0"/>
    <dbReference type="InParanoid" id="A0A1C7NJU0"/>
    <dbReference type="OrthoDB" id="666364at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005681">
        <property type="term" value="C:spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017862">
        <property type="entry name" value="SKI-int_prot_SKIP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004015">
        <property type="entry name" value="SKI-int_prot_SKIP_SNW-dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12096">
        <property type="entry name" value="NUCLEAR PROTEIN SKIP-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02731">
        <property type="entry name" value="SKIP_SNW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="3" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0747">Spliceosome</keyword>
    <feature type="domain" description="SKI-interacting protein SKIP SNW" evidence="5">
        <location>
            <begin position="188"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="218"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="327"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="508"/>
            <end position="555"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="579"/>
            <end position="599"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="14"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="329"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="354"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="398"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="523"/>
            <end position="534"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010197"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU367140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF02731"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OBZ89059.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="599" mass="66841" checksum="9A871B3B60963157" modified="2016-11-30" version="1">MASLSSLLPKPRQTLASNANTAPQLEKQINQLITKSTQSRIPPYGQRQSFRPRVAEDFGNGGAFPEIHIAQYPLGMGRKDNKAADRKGGALTLQVDADGNVKYDAIARQGHSDDRIIHSSYKDLVPINERKDMDVDKLVMDRPSEEEVQSVAEKTRLALEKIVNGKIKAAQPKNIGSTNGSGSNKDPTYIRYTPMQSQTGDGFNSGAKQRIIRMVDAPRDPMEPPNHLHKKVPRGPPSPPAPVMHSPPRKLTAKEQAEWVIPPCVSNWKNTKGYTIPLDKRLAADGRGLQELTINDNFAKFSEALYAADRHAREEVRQRNLMQQKLAQKQKEVEEDKLRQLAQKAREERAGFKPSSSAAEPPSNANRPSASSLMPDYDSSGSESGSESEEESSPVRGRRSDDSDEEGVRERDRLRHDRQKQRQREMRMSKMGTEARAKHLAREQGRDISEKIALGLAKPSLSKESMYDARLFNQTEGIGSGFGNDDSYNTYDKALFNQSSTSIYRYRGENTDSEVLGSTNTEDLERAIRQDKFSTRKGFQGTEGGESSSGPVEFEKETLAAAKSTSKDVFGLDTFLNKAKKGKRSRDDEEDSDDDRRKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NK71</accession>
    <name>A0A1C7NK71_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">RGS domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_02410</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000090">
        <property type="protein sequence ID" value="OBZ89532.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NK71"/>
    <dbReference type="FunCoup" id="A0A1C7NK71">
        <property type="interactions" value="15"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NK71"/>
    <dbReference type="InParanoid" id="A0A1C7NK71"/>
    <dbReference type="OrthoDB" id="196547at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.167.10">
        <property type="entry name" value="Regulator of G-protein Signalling 4, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016137">
        <property type="entry name" value="RGS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058855">
        <property type="entry name" value="RGS1/SST2-like_Fungal-DR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036305">
        <property type="entry name" value="RGS_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044926">
        <property type="entry name" value="RGS_subdomain_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10845:SF192">
        <property type="entry name" value="DOUBLE HIT, ISOFORM B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10845">
        <property type="entry name" value="REGULATOR OF G PROTEIN SIGNALING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00615">
        <property type="entry name" value="RGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25889">
        <property type="entry name" value="WHD_Fungal_DR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00315">
        <property type="entry name" value="RGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48097">
        <property type="entry name" value="Regulator of G-protein signaling, RGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50132">
        <property type="entry name" value="RGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RGS" evidence="2">
        <location>
            <begin position="513"/>
            <end position="668"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="694"/>
            <end position="727"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="716"/>
            <end position="727"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50132"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ89532.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="727" mass="83302" checksum="71D2E8342331F95F" modified="2016-11-30" version="1">MNTSNAHNSILRFTLDGRPSIEDIHDLFSILMSQLKCSTHKFMFRSYPNSFTSEQAIAVLISLNFTKTFQSNHYNLTARIVSNAFSNADTMNVSMSKALIQQFLWSRLILNATESRNRTYKDKGIWKISSKGLCILQDFCARTKTSLDKFDQHINDSAQLMFLVQIERTKDNDRLNSKRRHMASLFSIMIASLPLKKDYETSKSGFHSDQTSFTEDCQFNSSKNSTYSGHESPSSFKELLFADYFTNINILPNDMLVCTNGDNQQFVRSLESSQQKILLQNLEPSSNKLQMRTIFTSLICCNWLVEYCTVASIDEAESIMTDFMHLGWIAYHEEKNRFLHQIEASNSVTLSLTKSGMKAVVDMSIERYKDSQNMQLCSQQFDKLCMLERDNSEYDVFKRQDHVTSSASSTTSSVPHSGPAFLSQANEEKEKYYAKLRLPALSMHTTSSNSSMASSSSDDSFKVNSIFDIRSLSISPSISSFSFSNSKTDECEGPAHSNSHPIDYERKDTNADKLHLVLSNPYLRSLFRDFLDEHRCGELIEFWIDYQQFSQKYQEQKVASPSASLEQFLEDAFLFWETYLKPNSQFEVNIDIDLRNEMAREMPNIMTVVGTTSPNHLKTNILISTCPTAHAINTVKAWFEKANNQISNLMVTNFLTKFTCTTQYKTLLKLLQQKQAGQYNEESDSMLQTNLRRRSTAIQHSPRSAKELNYFPSPPRRQDSPKEILHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NK85</accession>
    <name>A0A1C7NK85_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DNA helicase Pif1-like 2B domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_02533</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000097">
        <property type="protein sequence ID" value="OBZ89408.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NK85"/>
    <dbReference type="STRING" id="101091.A0A1C7NK85"/>
    <dbReference type="InParanoid" id="A0A1C7NK85"/>
    <dbReference type="OrthoDB" id="3691720at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049163">
        <property type="entry name" value="Pif1-like_2B_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10492">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10492:SF57">
        <property type="entry name" value="ATP-DEPENDENT DNA HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21530">
        <property type="entry name" value="Pif1_2B_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA helicase Pif1-like 2B" evidence="1">
        <location>
            <begin position="81"/>
            <end position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF21530"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ89408.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="120" mass="13310" checksum="CE987F3EB925AB8B" modified="2016-11-30" version="1">MLNGKISLLQYIPQHYSLHTFVDSIYSKEEKAIIAPRNDTVDEINKYVLNQLPGDKTSLFAVDRITQEDSTGAVDCQMPAEYLQSLNPPGLPTSILELKVGMPDMVLRNISAERGLCNGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NL11</accession>
    <name>A0A1C7NL11_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_02142</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000077">
        <property type="protein sequence ID" value="OBZ89811.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NL11"/>
    <dbReference type="InParanoid" id="A0A1C7NL11"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="80"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="85"/>
            <end position="94"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ89811.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="103" mass="11693" checksum="80FC4E3E8DB0C86A" modified="2016-11-30" version="1">MLPVKLQFYCGRLYSNPNYSISSPDLGNDFDLGNDCKTRLPYHNAATHQHVSDLTAPIQRLRKELRRELPQGLSLELNVQEATMDEQNAKSTRQAEVPNDHGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NLH4</accession>
    <name>A0A1C7NLH4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Anaphase-promoting complex subunit 5</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">ANAPC5</name>
        <name evidence="8" type="ORF">A0J61_02253</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the APC5 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000082">
        <property type="protein sequence ID" value="OBZ89709.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NLH4"/>
    <dbReference type="FunCoup" id="A0A1C7NLH4">
        <property type="interactions" value="242"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NLH4"/>
    <dbReference type="InParanoid" id="A0A1C7NLH4"/>
    <dbReference type="OrthoDB" id="2504561at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005680">
        <property type="term" value="C:anaphase-promoting complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031145">
        <property type="term" value="P:anaphase-promoting complex-dependent catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045842">
        <property type="term" value="P:positive regulation of mitotic metaphase/anaphase transition"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070979">
        <property type="term" value="P:protein K11-linked ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037679">
        <property type="entry name" value="Apc5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026000">
        <property type="entry name" value="Apc5_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12830">
        <property type="entry name" value="ANAPHASE-PROMOTING COMPLEX SUBUNIT 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12830:SF9">
        <property type="entry name" value="ANAPHASE-PROMOTING COMPLEX SUBUNIT 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12862">
        <property type="entry name" value="ANAPC5"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="3" id="KW-0132">Cell division</keyword>
    <keyword evidence="4" id="KW-0498">Mitosis</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="Anaphase-promoting complex subunit 5" evidence="7">
        <location>
            <begin position="221"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="domain" description="Anaphase-promoting complex subunit 5" evidence="7">
        <location>
            <begin position="511"/>
            <end position="571"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00016066"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF12862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OBZ89709.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="633" mass="73566" checksum="B47D9DB7DAEAF756" modified="2016-11-30" version="1">MLHVGYVTPYRVTLLVLLDMFCHYRYTKELASKFVVFLTKSILNKTSFKQTCSEPTLQDIFAEINGFDSSPEIIEYIIHEIKDQLEKIQSPDRFQQFMKLYNDDEEGPTEGALILDKLSVFGIFIRRCRVEYENMSFKQLEDVQRAHTQYLSGLSGDAEFTTGLDPKAEGWVSDYNVKEFLKWQAEKIQKTGTTNIDVKSLHQWLQKIEKDVPDMVNIGQVRYLNYTRTKEYTNSLSCLNASFDLSLVKGVEIQYALLNLGILEHKFGHQWNAISALKDAVSAARANQDEYCLQEIQFWNEICQNGYAFDKRMTYSDKHLSNMKTLILARNMLRDGQSHRDVLKELQKSLTTIIMKDIDFMDRPQFLITSLAWLRYGNSVIGHCYLNLTNNSDDEYSSIEDIEKTAVAEARALYFSGKTDKAIQLLSDFSNRYESESDLLVGWRQAKAYMSRRRGITRTFFQMDEETETSRLVPPSDIDEYFEAIQSLSNKLILEKEFERAECVYDGMQKYAQDTNQRSQVCNSLILKAIYYLHTDSIDSCKATLIRAMRSSRECHDAKTYYYATIKLCELYVCLNNPDLLEKAVYMLESIFPKVLLMKNRLLNTDLHSVYHQALERKKKSLRSAASYQQSRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NLJ6</accession>
    <name>A0A1C7NLJ6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">A0J61_03762</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SGT1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000169">
        <property type="protein sequence ID" value="OBZ88184.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NLJ6"/>
    <dbReference type="FunCoup" id="A0A1C7NLJ6">
        <property type="interactions" value="83"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NLJ6"/>
    <dbReference type="InParanoid" id="A0A1C7NLJ6"/>
    <dbReference type="OrthoDB" id="296386at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032541">
        <property type="term" value="C:cortical endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005254">
        <property type="term" value="F:chloride channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.790:FF:000012">
        <property type="entry name" value="SGT1 homolog, MIS12 kinetochore complex assembly cochaperone"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.790">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007632">
        <property type="entry name" value="Anoctamin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049456">
        <property type="entry name" value="Anoctamin_N_fung"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049452">
        <property type="entry name" value="Anoctamin_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007052">
        <property type="entry name" value="CS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008978">
        <property type="entry name" value="HSP20-like_chaperone"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007699">
        <property type="entry name" value="SGS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12308">
        <property type="entry name" value="ANOCTAMIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12308:SF73">
        <property type="entry name" value="ANOCTAMIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04547">
        <property type="entry name" value="Anoctamin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20877">
        <property type="entry name" value="Anoctamin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04969">
        <property type="entry name" value="CS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05002">
        <property type="entry name" value="SGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13424">
        <property type="entry name" value="TPR_12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49764">
        <property type="entry name" value="HSP20-like chaperones"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51203">
        <property type="entry name" value="CS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51048">
        <property type="entry name" value="SGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0802">TPR repeat</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="228"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="260"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="336"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="380"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="419"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="469"/>
            <end position="491"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="6">
        <location>
            <begin position="809"/>
            <end position="842"/>
        </location>
    </feature>
    <feature type="domain" description="CS" evidence="9">
        <location>
            <begin position="873"/>
            <end position="964"/>
        </location>
    </feature>
    <feature type="domain" description="SGS" evidence="8">
        <location>
            <begin position="975"/>
            <end position="1062"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008509"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OBZ88184.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="1067" mass="122894" checksum="187DD2FC7275A4CB" modified="2016-11-30" version="1">MSEKELEPVVPSTEGFVHLFPPSAEIAPPIKPSQSDQTSTTSSIISCNGAIDYVIVFRFPTKVSSQSKTIRTKTELQQHVTFSLNNLLSRLTKANLRFQVISGKEEGVLLILISSPIGPIKQEYRRERVRDFLLGVRVDGLGDENELVDQAFHDLTEAERLRLVYEIITQPKSEGGCGISSQAEDYVESIMPLHDDDFNKAWYKSWSTKWLISDADLLKIRDHFGEKIAYYFAFLQTYFLWLSAPSAVGVLVYMTHSNTLAIWFSLFMMIWAILFIEMWKRKEATLAIQWNVRNFSKHEKRRAEFKGERMIKDQVTGEDTPFVSIWKLLGRRLSSLPGVALGAFFLSLIVGFVFVLQLFLHEYYNGPFRQFLHYAPTVGYVLLIPTMTKIYSHWVKILTDWEMHKTDASWEYSYTQKIFVANFLVSYLSLFITAWIYIPFGDYVLPYLAEFNISHEHKTVDFQRLRDQLVYFIVTGQLIGFLTEMVVPYVLKKVMPKAKRMTSKIHPKEQTTSMTDLDVKQTSIVDEEEKKLIAKIHKEAEMEEYNIYTDYVEMVVQFGYVSMFSTVWPLTALCSMLNNWVELRGDAIKLCKYTRRPIPHRAESIGPWIGNMETLVWLSSVTMGSFAYLFHPSTNIHSPYTPVSTLLAILISEHIFVALRAGIRQAFSMVPSLSEWLVRKEEYKLKKDWLERMIGNHKEFIARRDVDNDNDLAEGLSAKLWHDHLDRQVEVSYATELVQNTFKQQIYMQKLMMPFLTMTMTKLSLEPENAEFILRRCQVYQKLNKLDLALNDGQKALELLKEGSRSLLARAHLQLGITLHRLNRYSEAQTHLEQSKQLNPNEKTLATWLRKNTDKLPITPTPTQQVAQSTVSKPFARYEWFQNDTFVTIEVFIKKVKPEAVDLHFFEQALSLTVKLDTGSDYSLELEPLAHKVLPKESSYQVLSTKIEIKLKKQTSGIMWGALESENDQGTIMSTTASTTHKSKDWNKLVKEVDEDKPEGEQALNALFQQIYRDADPDTKRAMMKSFTESNGTCLSTNWAEVGSKKTEVKPPEGMIAKKCKEITPSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NLP2</accession>
    <name>A0A1C7NLP2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Rab-GAP TBC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_01926</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000067">
        <property type="protein sequence ID" value="OBZ90022.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="FunCoup" id="A0A1C7NLP2">
        <property type="interactions" value="2"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NLP2"/>
    <dbReference type="InParanoid" id="A0A1C7NLP2"/>
    <dbReference type="OrthoDB" id="294251at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031267">
        <property type="term" value="F:small GTPase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.270:FF:000016">
        <property type="entry name" value="TBC1 domain family member 2A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.270">
        <property type="entry name" value="putative rabgap domain of human tbc1 domain family member 14 like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.80">
        <property type="entry name" value="Ypt/Rab-GAP domain of gyp1p, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000195">
        <property type="entry name" value="Rab-GAP-TBC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035969">
        <property type="entry name" value="Rab-GAP_TBC_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050302">
        <property type="entry name" value="Rab_GAP_TBC_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47219:SF9">
        <property type="entry name" value="GTPASE ACTIVATING PROTEIN AND CENTROSOME-ASSOCIATED, ISOFORM B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47219">
        <property type="entry name" value="RAB GTPASE-ACTIVATING PROTEIN 1-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00566">
        <property type="entry name" value="RabGAP-TBC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00164">
        <property type="entry name" value="TBC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47923">
        <property type="entry name" value="Ypt/Rab-GAP domain of gyp1p"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50086">
        <property type="entry name" value="TBC_RABGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="340"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="domain" description="Rab-GAP TBC" evidence="2">
        <location>
            <begin position="155"/>
            <end position="347"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ90022.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="419" mass="49403" checksum="C44E6C67D8F01717" modified="2016-11-30" version="1">MIDTVREHNVPIWVALTNAQQQTESRLCRKVSSNLTARSSETDFSQITSSTSIHTFQRSCSSVSLSNRESDLRHQYEQRPEKLPDIAAEMEKWYAMTDRYGFLAEDAQKAVAISKEKEVERSEKWTHMATRVMLHGETLHQFVHSHKFKKRIFKGVPDCWRRDAWYYLVTDCLMSADHDHQLKQTYQKLLEKENSHERQIDLDIPRTLRDXIMFRQRYGSGQRALFNVLRAFANYDEEVGYCQGMTNIVATILMYCEEEKAFVILVHMFLRDKLHNLYIPGFPSLLESFFIQDNLLKRYIPKLFNHLAELGLSSDIYATRWYITLFAGGVIQYHTLIRIWDVYFLCGYDVFFFVAIALLKTYEARLLSYDLDLCMETLSSTMSVADDNQFLRQIEKLYERNVRHNLVQSLRKEYQAKHA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NN04</accession>
    <name>A0A1C7NN04_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Retinol dehydrogenase 14</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">RDH14</name>
        <name evidence="3" type="ORF">A0J61_03288</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000139">
        <property type="protein sequence ID" value="OBZ88644.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NN04"/>
    <dbReference type="STRING" id="101091.A0A1C7NN04"/>
    <dbReference type="InParanoid" id="A0A1C7NN04"/>
    <dbReference type="OrthoDB" id="191139at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43157:SF31">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL-GLYCAN BIOSYNTHESIS CLASS F PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43157">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL-GLYCAN BIOSYNTHESIS CLASS F PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="49"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ88644.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="376" mass="41800" checksum="602ADD5E244B5449" modified="2016-11-30" version="1">MVMLISVLLCFSFLIYFIIKVIVRANKQTTNTPSGLLEAANLELLNIPLPVFIRVYLIGIFETIYITCCHRGLFKHATTHKANEKLIDDWADAFQGPCGLAVITGGDSGIGREITHSLLAAGFQVILGAHSVQSCQQVMKELSQSTGSDKLSCIPLDLASIRSVHDFVDQVKLKAPNKDVQLLINNAGVMNVPYQSTMDGFESQCQINLLSPMLLTELLLPWIDKQCGRVLFASSSTLYAIRNLDTSWCKTSYRFQGLDHYAYSKACVAQLVSELAKTTDIKIYAYHPGTVRTRLFAHTVVFSLPIVSKLFDFIMFTPKEGSQTPLYLCLTKEPGASGTYWANTRPQALPSYLINGKKENTKALWNSVFYALESPY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NN29</accession>
    <name>A0A1C7NN29_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="17">Proliferation-associated SNF2-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="21" type="primary">HELLS</name>
        <name evidence="21" type="ORF">A0J61_01558</name>
    </gene>
    <organism evidence="21 22">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="21 22" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="21 22">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="16">Plays an essential role in normal development and survival. Involved in regulation of the expansion or survival of lymphoid cells. Required for de novo or maintenance DNA methylation. May control silencing of the imprinted CDKN1C gene through DNA methylation. May play a role in formation and organization of heterochromatin, implying a functional role in the regulation of transcription and mitosis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SNF2/RAD54 helicase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="21">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000051">
        <property type="protein sequence ID" value="OBZ90380.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NN29"/>
    <dbReference type="STRING" id="101091.A0A1C7NN29"/>
    <dbReference type="InParanoid" id="A0A1C7NN29"/>
    <dbReference type="OrthoDB" id="5857104at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005721">
        <property type="term" value="C:pericentric heterochromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003682">
        <property type="term" value="F:chromatin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006346">
        <property type="term" value="P:DNA methylation-dependent constitutive heterochromatin formation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044027">
        <property type="term" value="P:negative regulation of gene expression via chromosomal CpG island methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031508">
        <property type="term" value="P:pericentric heterochromatin formation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd18009">
        <property type="entry name" value="DEXHc_HELLS_SMARCA6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18793">
        <property type="entry name" value="SF2_C_SNF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.10810:FF:000015">
        <property type="entry name" value="lymphoid-specific helicase isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000577">
        <property type="entry name" value="lymphoid-specific helicase isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10810">
        <property type="entry name" value="Tandem AAA-ATPase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044753">
        <property type="entry name" value="HELLS_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038718">
        <property type="entry name" value="SNF2-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049730">
        <property type="entry name" value="SNF2/RAD54-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000330">
        <property type="entry name" value="SNF2_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47161">
        <property type="entry name" value="LYMPHOID-SPECIFIC HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47161:SF1">
        <property type="entry name" value="LYMPHOID-SPECIFIC HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00176">
        <property type="entry name" value="SNF2-rel_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="15" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="5" id="KW-0132">Cell division</keyword>
    <keyword evidence="12" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0217">Developmental protein</keyword>
    <keyword evidence="9 21" id="KW-0347">Helicase</keyword>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0498">Mitosis</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-0539">Nucleus</keyword>
    <keyword evidence="4" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="22" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="13" id="KW-0804">Transcription</keyword>
    <keyword evidence="11" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="19">
        <location>
            <begin position="248"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="20">
        <location>
            <begin position="627"/>
            <end position="779"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="18">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="18">
        <location>
            <begin position="124"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="18">
        <location>
            <begin position="201"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="18">
        <location>
            <begin position="518"/>
            <end position="539"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="18">
        <location>
            <begin position="831"/>
            <end position="865"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="18">
        <location>
            <begin position="7"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="18">
        <location>
            <begin position="22"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="18">
        <location>
            <begin position="134"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="18">
        <location>
            <begin position="202"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="18">
        <location>
            <begin position="833"/>
            <end position="842"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="18">
        <location>
            <begin position="843"/>
            <end position="859"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007025"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00053349"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00081399"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="EMBL" id="OBZ90380.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="865" mass="98992" checksum="1C73DAAF3D45AC9D" modified="2016-11-30" version="1">MNTSPKDISEPTTRDVSLEIDTPQSVSTDSPLQPASIASDQDIENIQVKDEYLDAGLSENIIAEEKAMEQNTMREQDKIMKEAQAQFDTTVKDQRMKRLNFLLEKSGAYATILGRKLAKQQEEARERAIQLDNQSTVEQQSQTEESKKPATRGRRGRPVSAANAKKRKTTDANYDLTDYLNEDDIKRRKQADGSVVKAIVEEQSTQTKKPKTATETVSTKPSISARQPALVTGAVLRDYQLAGVEWLISLWENGLNGILADEMGLGKTLQTIGFIAHLKSMQVSGPYLIVTPLSTLANWVNEFKRFAPSINVLLYHGSKEERHHLINRKMQKKKETSYEFPIIITSYEIVMNDRKHLQKYNWKYIVVDEGHRLKNMNCRLIRELKTYSSANRLLLTGTPLQNNLSELWSLLNFLLPDIFDDLDMFQSWFDFSDINDKSGQDRIIKEEEEDKIVSSLHTILRPFLLRRLKTDVEYALPKKKEYLLYAPLTQPQKNLYDAIIKRDLRDYLIKRKTVKDKTEQPEEAEIEEDNRRSKKKEVSYKEKSDRQFFKDLEKEPEEPKVDEDALARTQELAQAVKQVNGLHLQNLVMQLRKVCNHPFLFDWPIDPATNTPILSHELAAQSGKVLLLDRLLTGLFDRGHKVLVFSQMTKMLDILEDWATHLKGWPICRLDGSVSQEDRRRQIEEFSDPRSEIKLFLLSTRAGGLGINLTAADTVIIFDSDWNPQMDLQAQDRVHRIGQTKPVLIYRFVAAKTVEAKILERATAKRKLEKLVISKDKFKTPVASAKRAQESTISDLAEILASEDGEQVQIVAEGDKVISDADLEKLLDRSPSVFESGNTSDNELFREMDASEMHDERNEILATRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NN61</accession>
    <name>A0A1C7NN61_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Up-regulated during septation protein 1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">A0J61_02031</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000072">
        <property type="protein sequence ID" value="OBZ89906.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NN61"/>
    <dbReference type="STRING" id="101091.A0A1C7NN61"/>
    <dbReference type="InParanoid" id="A0A1C7NN61"/>
    <dbReference type="OrthoDB" id="5569911at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029191">
        <property type="entry name" value="Uds1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15456">
        <property type="entry name" value="Uds1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Up-regulated during septation protein 1" evidence="3">
        <location>
            <begin position="151"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="37"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="273"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="219"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="368"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="484"/>
            <end position="539"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="593"/>
            <end position="627"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="653"/>
            <end position="687"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="37"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="56"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="87"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="99"/>
            <end position="112"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF15456"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OBZ89906.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="699" mass="80610" checksum="FE83CDF4493ECE97" modified="2016-11-30" version="1">MIPLKQAHTDDRPNGLKFTRNNFPHFSAVKKEQDYSNQHYNHNNNNRTSTSSYGSQASLSPTLPTRSPFRIRDSLQQQQQQIKASHGNKSNTSSLDEPSTIYTSISSSSSSSANTVDDDLTHELQNIWKLKPIDTAIKQETIQIDSEDMLMQLLVSHAVIDSKEYPILSFEEYEQLKQHHSKLRNQISHASARLQLDKKIGATSHSLSNLSTNKNRESVMILLDEAVQADRKVKQLSEQLDRLKVEEVETEYRILQHTAGILSQGLQKLEKQSSLQSPMLSSPPLSSTSSSSSLSFQAQLSRTTSVKSKQKLQQLQSEIETITHALKSILKRYNLQSDSNSPTQLLSMLETQLQPESSFSSSIADRRVQQLEDQLSVAHDNEERVQQELQQEQAQVNQLKSVVSSMELQASKLHSQSQALYQREHALRNEMEQYRDQVFHLRKEKERLESGQNKTLSNGQDYSQVEQQQTQEYQAKLREQSVFLEKTARQCDELRTQHEQLSATCRNLEQMVQEKEKALDARDAQIRQLEAELAQQQQRQQTPLLHSAANQESLMQLQAMFSEKEAAWIEKSEAMEANYEGILREFDRLTGTAIEFETDKKNYERRISKLMKEVQDLESVLSQERTKHLNHSRDTATTASLRKEFYSMINSMKQDHERVLQREADEKKQLEKQLKDLKHERDMSRYERMNKGVQTLFMA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NNR4</accession>
    <name>A0A1C7NNR4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">MARVEL domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_01220</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000036">
        <property type="protein sequence ID" value="OBZ90727.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NNR4"/>
    <dbReference type="STRING" id="101091.A0A1C7NNR4"/>
    <dbReference type="InParanoid" id="A0A1C7NNR4"/>
    <dbReference type="OrthoDB" id="3253553at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="180"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="209"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="250"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="59"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="82"/>
            <end position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ90727.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="278" mass="30278" checksum="75D9B405AA26C662" modified="2016-11-30" version="1">MSNPFDEAGGRNPWSNPNEGPRFGNAYEDSTPVPAASASPALPPRKNSPFVAQRMPSPSDYSSPVNAWQESNKTLDEPDRNAWSSSPAPQPANAYQYSGTAYGNTSNTGNAYSSAVNNNDNNQTEAAPASQKIETQMSVNDTAHVAPPSGRPSKIRVLLRVILFIAAVGHLGFAAGASPAILSIIYSGFHIFLYMFRRFGSAQKLKRPILILCDLFMALMWGIGIIVEIAKYKCPPGQYNHWCDFYNTSIFFGFASFALYIVVLGWDVYGGMCAGKRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NP49</accession>
    <name>A0A1C7NP49_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">BZIP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">A0J61_01078</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the bZIP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000030">
        <property type="protein sequence ID" value="OBZ90885.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NP49"/>
    <dbReference type="STRING" id="101091.A0A1C7NP49"/>
    <dbReference type="InParanoid" id="A0A1C7NP49"/>
    <dbReference type="OrthoDB" id="674948at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006986">
        <property type="term" value="P:response to unfolded protein"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.170">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004827">
        <property type="entry name" value="bZIP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046347">
        <property type="entry name" value="bZIP_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044280">
        <property type="entry name" value="Hac1/HY5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46714">
        <property type="entry name" value="TRANSCRIPTIONAL ACTIVATOR HAC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46714:SF6">
        <property type="entry name" value="TRANSCRIPTIONAL ACTIVATOR HAC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07716">
        <property type="entry name" value="bZIP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00338">
        <property type="entry name" value="BRLZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57959">
        <property type="entry name" value="Leucine zipper domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50217">
        <property type="entry name" value="BZIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00036">
        <property type="entry name" value="BZIP_BASIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="6" id="KW-0834">Unfolded protein response</keyword>
    <feature type="domain" description="BZIP" evidence="9">
        <location>
            <begin position="77"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="38"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="56"/>
            <end position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023230"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OBZ90885.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="177" mass="19981" checksum="C37330BE73117B53" modified="2016-11-30" version="1">MTNNNNNNNNSDNNNSLADILSLPMDFAVDPLVATTTSIVSPLPPSPVASGNQKRKSIERDDSVASKKSRLSLDDKDQKTKERILRNRAAAQESRDKKRRYVSELESNNKQLTEQNEALNEQVKQLQAQNALITAQLEAITRQLTELPHMKFDNVHPILFNDFCDSARIVKKECLSY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NP75</accession>
    <name>A0A1C7NP75_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Ubiquitin-conjugating enzyme E2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">CDC34</name>
        <name evidence="7" type="ORF">A0J61_01070</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the ubiquitin-conjugating enzyme family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000030">
        <property type="protein sequence ID" value="OBZ90887.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NP75"/>
    <dbReference type="STRING" id="101091.A0A1C7NP75"/>
    <dbReference type="InParanoid" id="A0A1C7NP75"/>
    <dbReference type="OrthoDB" id="19692at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019005">
        <property type="term" value="C:SCF ubiquitin ligase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000082">
        <property type="term" value="P:G1/S transition of mitotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000086">
        <property type="term" value="P:G2/M transition of mitotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010828">
        <property type="term" value="P:positive regulation of D-glucose transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051865">
        <property type="term" value="P:protein autoubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000209">
        <property type="term" value="P:protein polyubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031146">
        <property type="term" value="P:SCF-dependent proteasomal ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030466">
        <property type="term" value="P:silent mating-type cassette heterochromatin formation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.110.10:FF:000051">
        <property type="entry name" value="ubiquitin-conjugating enzyme E2 R2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.110.10">
        <property type="entry name" value="Ubiquitin Conjugating Enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050113">
        <property type="entry name" value="Ub_conjugating_enzyme"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000608">
        <property type="entry name" value="UBC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023313">
        <property type="entry name" value="UBQ-conjugating_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016135">
        <property type="entry name" value="UBQ-conjugating_enzyme/RWD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24067">
        <property type="entry name" value="UBIQUITIN-CONJUGATING ENZYME E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00179">
        <property type="entry name" value="UQ_con"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00212">
        <property type="entry name" value="UBCc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54495">
        <property type="entry name" value="UBC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00183">
        <property type="entry name" value="UBC_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50127">
        <property type="entry name" value="UBC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <keyword evidence="2 4" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="UBC core" evidence="6">
        <location>
            <begin position="3"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="163"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="active site" description="Glycyl thioester intermediate" evidence="3">
        <location>
            <position position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU362109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OBZ90887.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="191" mass="21467" checksum="5AB3EB67B3136CFE" modified="2016-11-30" version="1">MASAANILQRQFKELTRNPVPGFVVDLKDDNIFEWDVALIGSPKTMYEGGYFKATMTFPDDYPFNPPTFKFNNEFYHPNVYPDGRLCISILHPPGEDPISGEKAEERWNPTQSVESVLVSIISLLADPNCSSPANVDAGVAYRKNRDMFESVVKKQVEASKKDIPNGFKMPTSEQDFMPTAPPEIEEDDNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NPG1</accession>
    <name>A0A1C7NPG1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">RING-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">A0J61_00936</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000025">
        <property type="protein sequence ID" value="OBZ91023.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NPG1"/>
    <dbReference type="InParanoid" id="A0A1C7NPG1"/>
    <dbReference type="OrthoDB" id="2288578at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004842">
        <property type="term" value="F:ubiquitin-protein transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036297">
        <property type="term" value="P:interstrand cross-link repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016567">
        <property type="term" value="P:protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037381">
        <property type="entry name" value="RFWD3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011016">
        <property type="entry name" value="Znf_RING-CH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16047:SF7">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE RFWD3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16047">
        <property type="entry name" value="RFWD3 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13639">
        <property type="entry name" value="zf-RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00744">
        <property type="entry name" value="RINGv"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="7">
        <location>
            <begin position="5"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="244"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="286"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="351"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="85"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="188"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="244"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="262"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="286"/>
            <end position="304"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OBZ91023.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="376" mass="42765" checksum="362A2E4297D9D130" modified="2016-11-30" version="1">MTYNCIICFGSLLSDPNESAAAAPCGHVFHNNCIRPWINQSKKCPLCKKTATIRHLVAPLYFSTTEDNETGESASSSSSDLTKRTRDLQVQLASSNREIESLRNELQLIRRQNADHILEIEAQNKKIRSMTNSMRYLKQVKRVADIDDYLSSPTSQSFMKSLQHQPHDQLITTLGGLEYRYKEAVRGRDNAESKLAINERAINSLKAKNEKLKDRLKEYEKGQGALRNRPRRKYANVIVLDSEDEGEEADVGNEIEDITLQQEDKQKERQPTENYNKYQTLEQSNQIEDHTSNQPASQSTSTIGNPLFRGIARDLALLSDDEEYAVEEHVSPMHNRFQYKXLNNELQLQAAGQSPKRLKTPSGHKSSLTIPDDDVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NPG5</accession>
    <name>A0A1C7NPG5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Dynactin subunit 6</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">Dctn6</name>
        <name evidence="7" type="ORF">A0J61_01168</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Part of the dynactin complex that activates the molecular motor dynein for ultra-processive transport along microtubules.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the dynactin subunits 5/6 family. Dynactin subunit 6 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000034">
        <property type="protein sequence ID" value="OBZ90789.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NPG5"/>
    <dbReference type="STRING" id="101091.A0A1C7NPG5"/>
    <dbReference type="InParanoid" id="A0A1C7NPG5"/>
    <dbReference type="OrthoDB" id="2355at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005869">
        <property type="term" value="C:dynactin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070840">
        <property type="term" value="F:dynein complex binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007052">
        <property type="term" value="P:mitotic spindle organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd04646">
        <property type="entry name" value="LbH_Dynactin_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.10.10">
        <property type="entry name" value="Hexapeptide repeat proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027777">
        <property type="entry name" value="DCTN6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011004">
        <property type="entry name" value="Trimer_LpxA-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13072">
        <property type="entry name" value="DYNACTIN 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13072:SF0">
        <property type="entry name" value="DYNACTIN SUBUNIT 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51161">
        <property type="entry name" value="Trimeric LpxA-like enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007719"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00016573"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00034687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OBZ90789.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="172" mass="18951" checksum="4BAD28ADE5B86B17" modified="2016-11-30" version="1">MSRNRITAGPKSVVCQETELRGEISIGSGTVLHPQCRVIAENGPIYIGKNNIIEENVIILNKHSAPLVIGDDNEFEVGCQIEGTRIGNNNIIEARGRILGSTAVGNYCVIGAGCSTENNETIPDFTVIYGLESKRRTQTEPLPTQATLHTRHLDYLREVLPKYNHLKKLETV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NPM5</accession>
    <name>A0A1C7NPM5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="12 16">ADP-ribosylation factor</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="primary">ARF_0</name>
        <name evidence="17" type="ORF">A0J61_00870</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">GTP-binding protein involved in protein trafficking; may modulate vesicle budding and uncoating within the Golgi apparatus.</text>
    </comment>
    <comment type="function">
        <text evidence="16">GTP-binding protein involved in protein trafficking; modulates vesicle budding and uncoating within the Golgi apparatus.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 16">Golgi apparatus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 15">Belongs to the small GTPase superfamily. Arf family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000023">
        <property type="protein sequence ID" value="OBZ91071.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NPM5"/>
    <dbReference type="FunCoup" id="A0A1C7NPM5">
        <property type="interactions" value="575"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NPM5"/>
    <dbReference type="InParanoid" id="A0A1C7NPM5"/>
    <dbReference type="OrthoDB" id="2011769at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016192">
        <property type="term" value="P:vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd04150">
        <property type="entry name" value="Arf1_5_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:003500">
        <property type="entry name" value="ADP-ribosylation factor 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045872">
        <property type="entry name" value="Arf1-5-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024156">
        <property type="entry name" value="Small_GTPase_ARF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006689">
        <property type="entry name" value="Small_GTPase_ARF/SAR"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11711">
        <property type="entry name" value="ADP RIBOSYLATION FACTOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00025">
        <property type="entry name" value="Arf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00328">
        <property type="entry name" value="SAR1GTPBP"/>
    </dbReference>
    <dbReference type="SMART" id="SM00177">
        <property type="entry name" value="ARF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00175">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00178">
        <property type="entry name" value="SAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51417">
        <property type="entry name" value="ARF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 16" id="KW-0931">ER-Golgi transport</keyword>
    <keyword evidence="8 16" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="9 13 15" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="10 16" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="14" id="KW-0460">Magnesium</keyword>
    <keyword evidence="14" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 16" id="KW-0519">Myristate</keyword>
    <keyword evidence="5 13 15" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7 16" id="KW-0653">Protein transport</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 16" id="KW-0813">Transport</keyword>
    <feature type="binding site" evidence="13">
        <location>
            <begin position="24"/>
            <end position="31"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="31"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="48"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="70"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <begin position="126"/>
            <end position="129"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00053326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00070396"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR606689-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PIRSR" id="PIRSR606689-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="RuleBase" id="RU003925"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="RuleBase" id="RU369003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="OBZ91071.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="181" mass="20708" checksum="52A95CF8A4EF7E99" modified="2016-11-30" version="1">MGLSFSKLFNDLFGKKEMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKNISFTVWDVGGQDKIRPLWRHYFQNTQGIIFVVDSNDRDRISEARDELQRMLNEDELRDALLLVFANKQDLPNAMNAAEITDKLGLHSLRNRRWYIQTTCATSGDGLYEGLEWLSNNLKRGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NQR1</accession>
    <name>A0A1C7NQR1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">CCT-beta</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">cct2</name>
        <name evidence="11" type="ORF">A0J61_00485</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Molecular chaperone; assists the folding of proteins upon ATP hydrolysis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Component of the T-complex protein 1 (TCP1) complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the TCP-1 chaperonin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000011">
        <property type="protein sequence ID" value="OBZ91457.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NQR1"/>
    <dbReference type="FunCoup" id="A0A1C7NQR1">
        <property type="interactions" value="946"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NQR1"/>
    <dbReference type="InParanoid" id="A0A1C7NQR1"/>
    <dbReference type="OrthoDB" id="10248520at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005832">
        <property type="term" value="C:chaperonin-containing T-complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd03336">
        <property type="entry name" value="TCP1_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.260.10:FF:000025">
        <property type="entry name" value="Chaperonin containing TCP1 subunit 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.50.7.10:FF:000002">
        <property type="entry name" value="T-complex protein 1 subunit beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.560.10:FF:000017">
        <property type="entry name" value="T-complex protein 1 subunit eta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.7.10">
        <property type="entry name" value="GroEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.560.10">
        <property type="entry name" value="GroEL-like equatorial domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.260.10">
        <property type="entry name" value="TCP-1-like chaperonin intermediate domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012716">
        <property type="entry name" value="Chap_CCT_beta"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017998">
        <property type="entry name" value="Chaperone_TCP-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002194">
        <property type="entry name" value="Chaperonin_TCP-1_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002423">
        <property type="entry name" value="Cpn60/GroEL/TCP-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027409">
        <property type="entry name" value="GroEL-like_apical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027413">
        <property type="entry name" value="GROEL-like_equatorial_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027410">
        <property type="entry name" value="TCP-1-like_intermed_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053374">
        <property type="entry name" value="TCP-1_chaperonin"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02341">
        <property type="entry name" value="chap_CCT_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF041083">
        <property type="entry name" value="thermosome_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11353">
        <property type="entry name" value="CHAPERONIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00118">
        <property type="entry name" value="Cpn60_TCP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00304">
        <property type="entry name" value="TCOMPLEXTCP1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52029">
        <property type="entry name" value="GroEL apical domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48592">
        <property type="entry name" value="GroEL equatorial domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54849">
        <property type="entry name" value="GroEL-intermediate domain like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00750">
        <property type="entry name" value="TCP1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00751">
        <property type="entry name" value="TCP1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00995">
        <property type="entry name" value="TCP1_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8 10" id="KW-0143">Chaperone</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011381"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00033237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU004187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="OBZ91457.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="526" mass="56786" checksum="D6BF38C6B4417DEA" modified="2016-11-30" version="1">MSLAPVNIFQDQATEERAENARLSSFIGAIAVGDLVKSTLGPKGMDKILQSASTGEILVTNDGATILKSIALDNAAAKVLVNISKVQDDEVGDGTTSVCVLAAELLREAEQLVNQHIHPQTIIEGYRLASAAAYKTLEASAVDHSQDTALFRQDLINIAKTTLSSKVLSQDKEYFAELAVDAVLRLKGSTNLENIQIIKKPGGKLMDSYLDEGFILDKKIGVNCPKRIENANILIANTSMDTDKIKIFGARVRVDATGKLAELERAERDKMKEKVEKIKAHGINCFVNRQLIYNWPEQLLADSGIATIEHADFEGVERLALVTGGEIASTFDHPELVKLGHCDLIEEVIIGEDKLIKFSGVAAGEACTIVLRGATHQLLDEAERSLHDALSVLSQTVREPRTVLGGGCSEMLMSKAVDEVAAKTAGKRAIAAESFSKALRQMPTILADNAGFDSSELVSQLRAAHYDGQSTAGLDMVNGAVADVRELGITESYKLKKQVLLSASEAAEMILRVDNIIRCAPRQRQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NQS7</accession>
    <name>A0A1C7NQS7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Riboflavin kinase</fullName>
            <ecNumber evidence="5">2.7.1.26</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="17">ATP:riboflavin 5'-phosphotransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="16">Flavin mononucleotide kinase 1</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="15">Flavokinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="19" type="primary">fmn1_1</name>
        <name evidence="19" type="ORF">A0J61_00639</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="19 20" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19 20">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Catalyzes the phosphorylation of riboflavin (vitamin B2) to form flavin mononucleotide (FMN) coenzyme.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Cofactor biosynthesis; FMN biosynthesis; FMN from riboflavin (ATP route): step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the flavokinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="19">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.26" evidence="5"/>
    <dbReference type="EMBL" id="LUGH01000015">
        <property type="protein sequence ID" value="OBZ91310.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NQS7"/>
    <dbReference type="FunCoup" id="A0A1C7NQS7">
        <property type="interactions" value="353"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NQS7"/>
    <dbReference type="InParanoid" id="A0A1C7NQS7"/>
    <dbReference type="OrthoDB" id="276388at2759"/>
    <dbReference type="UniPathway" id="UPA00276">
        <property type="reaction ID" value="UER00406"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008531">
        <property type="term" value="F:riboflavin kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009398">
        <property type="term" value="P:FMN biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009231">
        <property type="term" value="P:riboflavin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.30.30:FF:000002">
        <property type="entry name" value="Riboflavin kinase, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.30">
        <property type="entry name" value="Riboflavin kinase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023468">
        <property type="entry name" value="Riboflavin_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015865">
        <property type="entry name" value="Riboflavin_kinase_bac/euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023465">
        <property type="entry name" value="Riboflavin_kinase_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22749:SF6">
        <property type="entry name" value="RIBOFLAVIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22749">
        <property type="entry name" value="RIBOFLAVIN KINASE/FMN ADENYLYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01687">
        <property type="entry name" value="Flavokinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00904">
        <property type="entry name" value="Flavokinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82114">
        <property type="entry name" value="Riboflavin kinase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="14" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="8" id="KW-0288">FMN</keyword>
    <keyword evidence="12 19" id="KW-0418">Kinase</keyword>
    <keyword evidence="10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0808">Transferase</keyword>
    <keyword evidence="13" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Riboflavin kinase" evidence="18">
        <location>
            <begin position="20"/>
            <end position="152"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00003572"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012105"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00017394"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00029789"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00029960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00077632"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="SMART" id="SM00904"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="OBZ91310.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="170" mass="19232" checksum="199E74019F17FCDE" modified="2016-11-30" version="1">MSTDNINTDRPLIVGPEKLEAPYPISVSGTVVKGFGRGSKELGIPTANLNEEALNEMFNECETGVYYGWSQVGEKDSTVYPMVMSLGWNPYYKNEKKSAEVHILHEFESDFYGESIRIIVTGYIRPEQNYPSLDALIRDIKTDIEVARQSLKREAYGAIRHDTLFSKKTN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NQX6</accession>
    <name>A0A1C7NQX6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Mitochondrial zinc maintenance protein 1, mitochondrial</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">A0J61_02297</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Assembly factor required for Rieske Fe-S protein RIP1 incorporation into the cytochrome b-c1 (CIII) complex. Functions as a chaperone, binding to this subunit within the mitochondrial matrix and stabilizing it prior to its translocation and insertion into the late CIII dimeric intermediate within the mitochondrial inner membrane. Modulates the mitochondrial matrix zinc pool.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Interacts with RIP1.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion matrix</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the complex I LYR family. MZM1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000084">
        <property type="protein sequence ID" value="OBZ89664.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NQX6"/>
    <dbReference type="FunCoup" id="A0A1C7NQX6">
        <property type="interactions" value="94"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NQX6"/>
    <dbReference type="InParanoid" id="A0A1C7NQX6"/>
    <dbReference type="OrthoDB" id="529194at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044183">
        <property type="term" value="F:protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034551">
        <property type="term" value="P:mitochondrial respiratory chain complex III assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd20267">
        <property type="entry name" value="Complex1_LYR_LYRM7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045298">
        <property type="entry name" value="Complex1_LYR_LYRM7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050435">
        <property type="entry name" value="MZM1/LYRM7"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46749">
        <property type="entry name" value="COMPLEX III ASSEMBLY FACTOR LYRM7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46749:SF1">
        <property type="entry name" value="COMPLEX III ASSEMBLY FACTOR LYRM7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0143">Chaperone</keyword>
    <keyword evidence="6" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0809">Transit peptide</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004305"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009949"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011589"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00015108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00025268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OBZ89664.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="107" mass="12498" checksum="43C1ED84774DCA31" modified="2016-11-30" version="1">MSIYPSKQAAIDAYRHLLKIQRNVFSGDQKAIKAAKKETYSRFMQHKNETNVDILDQKLKLADQIANFLEQNSVKVVREEAESTPRLNIKGRKDNMRFDDVAWQMNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NRA7</accession>
    <name>A0A1C7NRA7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Apoptosis 2 inhibitor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">Iap2</name>
        <name evidence="4" type="ORF">A0J61_00384</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000008">
        <property type="protein sequence ID" value="OBZ91558.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NRA7"/>
    <dbReference type="STRING" id="101091.A0A1C7NRA7"/>
    <dbReference type="InParanoid" id="A0A1C7NRA7"/>
    <dbReference type="OrthoDB" id="2196114at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00022">
        <property type="entry name" value="BIR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1170.10">
        <property type="entry name" value="Inhibitor Of Apoptosis Protein (2mihbC-IAP-1), Chain A"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051190">
        <property type="entry name" value="Baculoviral_IAP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001370">
        <property type="entry name" value="BIR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46771">
        <property type="entry name" value="DETERIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46771:SF5">
        <property type="entry name" value="DETERIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00653">
        <property type="entry name" value="BIR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00238">
        <property type="entry name" value="BIR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57924">
        <property type="entry name" value="Inhibitor of apoptosis (IAP) repeat"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50143">
        <property type="entry name" value="BIR_REPEAT_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="192"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="259"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="315"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="376"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="421"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="508"/>
            <end position="551"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="192"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="285"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="322"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="382"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="423"/>
            <end position="442"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OBZ91558.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="624" mass="70989" checksum="5B0B0020C0E52270" modified="2016-11-30" version="1">MNILQNRIESFKKTPNPWPHTDLRYDIEAFAKAGFYHVRRPRIADSVRCFLCDLEVSQWTKARSPYLRHTKESPQCPWVLLNFPDTSNSTEMVHQTLNSPTMQKARLLTFQHHNYWPPHKGKQTRAKKYPAAYKVADAGFFLSPTLKEPAQIKCPYCQVTISEPDQEIDLLQKHQVLSSQCPFLKLKLNTGTSRDTTNSLQSSESFKTASSQLHQEENMQRKRKQMEPVKQQTRFVKQKIESIKEDQAKEETIWDIDGTFSATPPHIKKPAITFGKQSSRRDRKRERVLPSSKRESAIDIFSEALEPTFQLKQEVQMSSKTQIEKQQPKEQPKEQSKEKAKEQFEKQNSSAMRKAEISIAPRFIDHNPTYQQAEVAVTISSPKRDKGKGRAVESPASIAYTANRLSNQSSPRLSLQLKKPISLSKSKAPSTSPPRSTHSISLRHSLPEQKEEEEAIYFDHPLSPRHSVQFLQSTPVHKNRSNQVSAADIFGDCPFSPIVQTTAHQQHDSMTPSLATPSRIRPSVSQSESKRWRAFSPPKSPSFITEDTPPILSMGDIVPQLPPARISSEQKTMTVENFLQNTIEASIHKVKEHGSHVIEMIKQKSNQVKSELLQQTTGTSSQSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NRB8</accession>
    <name>A0A1C7NRB8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_00375</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000008">
        <property type="protein sequence ID" value="OBZ91568.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NRB8"/>
    <dbReference type="InParanoid" id="A0A1C7NRB8"/>
    <dbReference type="OrthoDB" id="2273034at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="39"/>
            <end position="69"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ91568.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="71" mass="8214" checksum="CAD059AF0934DB19" modified="2016-11-30" version="1">MSALHPKNTSEAKAFEEEGVKSQLGQYVDVQERVVNEMKKDSNVDKEQLEREISNLRSLKKEQELLSKDNH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NSD4</accession>
    <name>A0A1C7NSD4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Ribosome-associated complex subunit SSZ1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">SSZ1</name>
        <name evidence="4" type="ORF">A0J61_01757</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the heat shock protein 70 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000059">
        <property type="protein sequence ID" value="OBZ90204.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NSD4"/>
    <dbReference type="FunCoup" id="A0A1C7NSD4">
        <property type="interactions" value="22"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NSD4"/>
    <dbReference type="InParanoid" id="A0A1C7NSD4"/>
    <dbReference type="OrthoDB" id="29851at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0101031">
        <property type="term" value="C:protein folding chaperone complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051083">
        <property type="term" value="P:'de novo' cotranslational protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002181">
        <property type="term" value="P:cytoplasmic translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006450">
        <property type="term" value="P:regulation of translational fidelity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006452">
        <property type="term" value="P:translational frameshifting"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd10232">
        <property type="entry name" value="ASKHA_NBD_HSP70_ScSsz1p-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.640.10:FF:000010">
        <property type="entry name" value="heat shock 70 kDa protein 14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.640.10">
        <property type="entry name" value="Actin, Chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.34.10">
        <property type="entry name" value="Substrate Binding Domain Of DNAk, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029047">
        <property type="entry name" value="HSP70_peptide-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013126">
        <property type="entry name" value="Hsp_70_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45639:SF32">
        <property type="entry name" value="HEAT SHOCK PROTEIN PDR13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45639">
        <property type="entry name" value="HSC70CB, ISOFORM G-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00012">
        <property type="entry name" value="HSP70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00301">
        <property type="entry name" value="HEATSHOCK70"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100920">
        <property type="entry name" value="Heat shock protein 70kD (HSP70), peptide-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007381"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OBZ90204.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="545" mass="58635" checksum="DA9586FFCA246917" modified="2016-11-30" version="1">MSESNTVIGINFGTAYTSIAYINKEGRADCLANEEGDRQIASALAFHGEEEVIGSQAKSDIARHPNHTIANFRANIGKSFADAQNLTGSAAPVVDKNGVPAYEIELPAGKSVFTAQEVSTKYLKHIRESAEAFLGTQINGAVLAAPSYFTEKQREELVAAAEAAGIKVIQLVHESAAAALAYGVGQEATTKDPQDKIIVVCDLGGHSFDVTVLAVRSGMFQILATAHDTKVGGASFDDLLIKHFTAEFQKKAKIDISSNKKALAKLRNAVEVTKKMLSSANSAPCFVESLAEGVDFHSTINRMRFELLSKAVFSQLQNVINEVLEKSQLDASEVDEVLLAGGSARIPKFANKVREVFTSENTKVLNELEADEVVARGCAIQGSLVAGFEKEDIDAAIHPVVTLAPNTTKAIGVLNAKGEFVTIIPRGTSLPARRVFEFSNAEANQTHAYVALYEGDHTVEKHEIKHEPVPVEDDEEPYEEEPEIVTKVFNKPAAQLIEASLPLANGAKEKGSKIEVQITVDAQANLSLVLREKNSSNVVKAEAKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NU49</accession>
    <name>A0A1C7NU49_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">BAR-domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">A0J61_00908</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000024">
        <property type="protein sequence ID" value="OBZ91034.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NU49"/>
    <dbReference type="FunCoup" id="A0A1C7NU49">
        <property type="interactions" value="444"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NU49"/>
    <dbReference type="InParanoid" id="A0A1C7NU49"/>
    <dbReference type="OrthoDB" id="14167at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00174">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.60">
        <property type="entry name" value="Arfaptin homology (AH) domain/BAR domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.40">
        <property type="entry name" value="SH3 Domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027267">
        <property type="entry name" value="AH/BAR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004148">
        <property type="entry name" value="BAR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050384">
        <property type="entry name" value="Endophilin_SH3RF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036028">
        <property type="entry name" value="SH3-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001452">
        <property type="entry name" value="SH3_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14167:SF116">
        <property type="entry name" value="CAP, ISOFORM AC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14167">
        <property type="entry name" value="SH3 DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03114">
        <property type="entry name" value="BAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00018">
        <property type="entry name" value="SH3_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00452">
        <property type="entry name" value="SH3DOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00721">
        <property type="entry name" value="BAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00326">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103657">
        <property type="entry name" value="BAR/IMD domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50044">
        <property type="entry name" value="SH3-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51021">
        <property type="entry name" value="BAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50002">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0728">SH3 domain</keyword>
    <feature type="domain" description="BAR" evidence="6">
        <location>
            <begin position="13"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="domain" description="SH3" evidence="5">
        <location>
            <begin position="334"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="228"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="416"/>
            <end position="515"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="157"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="273"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="431"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="443"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="481"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="501"/>
            <end position="514"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51021"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OBZ91034.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="550" mass="61770" checksum="A7902F3DBDD9985F" modified="2016-11-30" version="1">MIKNIGKFRQWTEEKLGNAKITLQTEDFQRLEVETERKRIAYEKLHASTVLLQSQLVKRKISPEDNKSKRLPNDMVGVCMTNYGNEFTDDAALGVASINFGQAQSKLASLQEEYADSMKSIYLEKLDDGLTQFREYQQLRKKLESRRLDYDSKLGRLQKSKKEKPELEQEMQAAKLKYEDSEYDVIQKMAALQEFEDVHCEALEHLLDIQMNYLSRSLEVLSDVKNNWGARQNGATPRRMTELSRSPSNHSGDENGPMNGLRSPAVTPRKYSVGSNRSGSYDNTLTPPPMALSNSNTTRRMPPPSRTNSNLSEEAPRSVPPVLPRRQSQTVEAPIKNQRKAAYEFDGENADELSFHVGDIIQVVEEVDEGWWLGEVIEPNGSVRRGIFPVNYTEAISHSAGPPMPARPVLASPHYEEPEDLNASPFHDRSTNNGFSYIRPNNSQPSRTVSSSTISPASSPIPQHKMVASSKRAPPPPPSSRPSIHNSRSSSTSNMKPIRTGPSTPQLHVTQTDNYFDDSHSSTSCQECGCVDYSANVFKKGHCNNCFHKH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-06-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7M2F7</accession>
    <name>A0A1C7M2F7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_11889</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01002646">
        <property type="protein sequence ID" value="OBZ71075.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7M2F7"/>
    <dbReference type="InParanoid" id="A0A1C7M2F7"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ71075.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="138" mass="15552" checksum="98C9443A96C594FA" modified="2016-11-30" version="1">MTAADMPINMGMNEDTPLSTDNQVTESEAIVNENADSEMTEADVANSINEHDSFPNSITFNWLPPRSMNSFDEMALEFRCLLDEAKTARLYQRKIAKLHYSANFAIGDINLFIMLPSKFCSPTTKKCQPGLFYLTLNQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MTC0</accession>
    <name>A0A1C7MTC0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_11816</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01002532">
        <property type="protein sequence ID" value="OBZ80135.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MTC0"/>
    <dbReference type="InParanoid" id="A0A1C7MTC0"/>
    <dbReference type="OrthoDB" id="2610923at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ80135.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="251" mass="28788" checksum="6A4E0C2A25EF66C4" modified="2016-11-30" version="1" fragment="single">LARSYKSVCRRVDLPTVRLFLDCKTRWKSNYDLLEVALGQLVAYNCVFKDLDARDKDRCLKINSNEEASLVRLRDVLKSLSDATKWASASKYLTIDCTCFYYDYVFCALEEAMVKAKFGYLDDEPKKVCLYEILSERESIIKSKPPGLDELVLKGRLVRHEKPIRYFYKTKVCSAYGIGTAMNSRLKLGLWEKDHWKQYGCPASINVRANWVDEYQHVEGTFGSLALGDDNDDDEMAGLYAKFLAMNKSLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MTL9</accession>
    <name>A0A1C7MTL9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_11719</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01002383">
        <property type="protein sequence ID" value="OBZ80231.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MTL9"/>
    <dbReference type="InParanoid" id="A0A1C7MTL9"/>
    <dbReference type="OrthoDB" id="2422867at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ80231.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="111" mass="12670" checksum="9931B12EEF74EF92" modified="2016-11-30" version="1" fragment="single">YQLFNTERSKTMYEYVIGLQNKGYEVVYTLDEDNRLNAIFFAPKSGVECARRMPENLVIDATYKINTHKLTFVNIVGTSSVESTEPGTLMTFEVAGAFISEEGNNHYEWVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MTW3</accession>
    <name>A0A1C7MTW3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_11626</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01002273">
        <property type="protein sequence ID" value="OBZ80325.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="InParanoid" id="A0A1C7MTW3"/>
    <dbReference type="OrthoDB" id="3248986at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="328"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ80325.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="328" mass="37866" checksum="BD45C388D347F943" modified="2016-11-30" version="1" fragment="single">MPATSTSNCFVYRFCDVCKCSPREDRFITRSIHRSHQLYRKYNGMAYQDWVKTYXKHSRYGRIAKSTPPIFIPSKNITNEPEQTLVPVEGVREDIQYYDECDSEEDEDAVAEVANAMSVSEPTNVQPAPVSELDLIYLFHLADKIPQTPFSKVLFKSVLKMHNNNIPNLQVESYMQDLNEALEIQGDKFRFPKTVTTLLKRSHLHTMSSDGIKYYAVCPVCHHLSDQKEHPTADDIECNQSLIGAPYKPTGSSEFCNGRVYDYDGSREVPKHVVQKEYPYCSIVATLKKFFLRRGFADKIVEWNNRETVDGYYLDLYDAPRFSQFKTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MU99</accession>
    <name>A0A1C7MU99_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_11548</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01002176">
        <property type="protein sequence ID" value="OBZ80403.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MU99"/>
    <dbReference type="InParanoid" id="A0A1C7MU99"/>
    <dbReference type="OrthoDB" id="2441332at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ80403.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="226" mass="25402" checksum="ADB0968B77BD4AB8" modified="2016-11-30" version="1" fragment="single">VDEIKQAGEEIEKLQKILVTRHKSFLNIDRPDIKQDNYSYLDILVFRALLKKRKREHDDADATSSVIADDMSNASSHFTDTTSSTVVLDRQSLPPSVHSASTSDELVNALRNIRETAYGSRQQEEKLNAVQNLCLNHIFFVSARRSRSVGKYLTFNQHACLLSLESVVLPRVDSSVNRLAKRLEEAAMNLGIKYAGAVDEMETITTKGVLELNRQSRTYASALIYA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MUX4</accession>
    <name>A0A1C7MUX4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_11394</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001986">
        <property type="protein sequence ID" value="OBZ80557.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MUX4"/>
    <dbReference type="InParanoid" id="A0A1C7MUX4"/>
    <dbReference type="OrthoDB" id="2382535at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ80557.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="283" mass="32089" checksum="5C76E888D8650717" modified="2016-11-30" version="1">MAWHIKTGSKLTHFVLKPVDDRIAKSTPPIFIPSKNNTDEPEQTLENQVPVEGDREDIQYYDECDTKEDEEAVAEIANAMSVSEPTNVQPAPVSELDLISDKIPQTPFFKVLFKSVLKMHNNNIPNLQVESYMQDLNEALEIQGAFTAADIECNESLIGAPYKPTGSGEFCNGRVYDYDGSKEMPKLVVQKENPYCSMVATLKNFFLRRGFADKIVEWKDCETVDGYYLNLYDAPEFSQFKTSPNDPTSFVLSGSYNLLLTLNDDWFSSFEATYNIKYLYLAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2024-01-24" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MVI0</accession>
    <name>A0A1C7MVI0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_11080</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001654">
        <property type="protein sequence ID" value="OBZ80871.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MVI0"/>
    <dbReference type="InParanoid" id="A0A1C7MVI0"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="163"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ80871.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="202" mass="21194" checksum="4FF20C7EB448E38E" modified="2016-11-30" version="1" fragment="single">ATPVANPATASQISPQQAQIIQQLMLQRNLNAMRGRGRGQVPLTQQQIAAFQAMRQQSAAAAAAAANGLLRGNPAAGPGNGANGLNMQDINRTAMMAGLNQNRLNQAALQAAAAAAVSGGANNLQPNAAAAALLSQQQQFQMSLQFQQAAAAAAAQQQRNNMLNFQQQQQQQQQQQQQQQQQQQQGSNTPNSTGSNNNANMS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MVP1</accession>
    <name>A0A1C7MVP1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">RRM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">A0J61_11465</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01002064">
        <property type="protein sequence ID" value="OBZ80486.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MVP1"/>
    <dbReference type="STRING" id="101091.A0A1C7MVP1"/>
    <dbReference type="InParanoid" id="A0A1C7MVP1"/>
    <dbReference type="OrthoDB" id="339151at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990861">
        <property type="term" value="C:Ubp3-Bre5 deubiquitination complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016579">
        <property type="term" value="P:protein deubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034517">
        <property type="term" value="P:ribophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00590">
        <property type="entry name" value="RRM_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039539">
        <property type="entry name" value="Ras_GTPase_bind_prot"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10693:SF20">
        <property type="entry name" value="AT27578P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10693">
        <property type="entry name" value="RAS GTPASE-ACTIVATING PROTEIN-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="3">
        <location>
            <begin position="215"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="289"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="29"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="93"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="141"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="291"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="316"/>
            <end position="330"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OBZ80486.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="339" mass="37442" checksum="5FAB277AF814070C" modified="2016-11-30" version="1">MMKPVETIVIERADSPVPVVGEKKKKSHGDKASKAEAKAEQKAETVKAEPKVETKPETKVEPKAEVKTETVKAESKVEAKPEPKVEQKTEQKQQQQQQQQQQQQQQQQQQQQQQQQTEKINPPPTQASPKPSAPKTWANLTAAAAAPSPTSTAAAPSATPAATPTNTTITPAAAAVTGNSTTPSIPATTSTPNTEKTNEKPQNKNQSNRKIIDPTQIFVKLVNESVHEEQLLEAFNKFGTVKSCNIARQRSCAFVEFASPDACQKALAQHKVTLSNGQHVLAEERRYNVGQQNNHQRYQNNRPQNNSFDQRRSNNNRRQNQQNQNTRQQQGKGRGSGNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MVP9</accession>
    <name>A0A1C7MVP9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Zinc finger protein bud20</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">bud20</name>
        <name evidence="13" type="ORF">A0J61_11114</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the ZNF593/BUD20 C2H2-type zinc-finger protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001686">
        <property type="protein sequence ID" value="OBZ80837.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MVP9"/>
    <dbReference type="FunCoup" id="A0A1C7MVP9">
        <property type="interactions" value="253"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7MVP9"/>
    <dbReference type="InParanoid" id="A0A1C7MVP9"/>
    <dbReference type="OrthoDB" id="24683at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030687">
        <property type="term" value="C:preribosome, large subunit precursor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043023">
        <property type="term" value="F:ribosomal large subunit binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000055">
        <property type="term" value="P:ribosomal large subunit export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000299">
        <property type="entry name" value="Zinc finger protein 593"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051879">
        <property type="entry name" value="C2H2-ZF_Maturation_Protein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022755">
        <property type="entry name" value="Znf_C2H2_jaz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46095">
        <property type="entry name" value="ZINC FINGER PROTEIN 593"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46095:SF1">
        <property type="entry name" value="ZINC FINGER PROTEIN 593"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12171">
        <property type="entry name" value="zf-C2H2_jaz"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <keyword evidence="6 10" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="12">
        <location>
            <begin position="59"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="93"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="118"/>
            <end position="129"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00038064"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="OBZ80837.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="129" mass="15315" checksum="974EFA0220FB99A6" modified="2016-11-30" version="1">MGRLRRKRTHHGIRDNYRKQRTRAYTRDLDQIHDDLKPENIDKKKHQEIDTDLPGLGQFYCVECARHFISEHHMNEHLKSKLHKRRLKKLEDEPYTQEEADRAAGIGKTDNGKRGVRLTTTQQDVAMED</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MWC2</accession>
    <name>A0A1C7MWC2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_10848</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001443">
        <property type="protein sequence ID" value="OBZ81103.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7MWC2"/>
    <dbReference type="InParanoid" id="A0A1C7MWC2"/>
    <dbReference type="OrthoDB" id="2289822at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ81103.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="512" mass="58259" checksum="52EE55C23339550F" modified="2016-11-30" version="1">MLKQFPGDYVEALINEKDMLLKENLIDVACLPKTNNIHSFLRSFVQEMREVSVEGMVVPVGSNTFHLKVRLVGSFGDIPSVSDINYLSGRSYYWPCRFCTIRPCKVGCLGQAANDQKDPCRERTLEDFLFGDAAHGVKNSSIFKKLLSFSSPMFMGVDIFHLLILNIAKQLKSFLERRGCPLHSKRTYRQNIGIMIEVQASSMPDILVGEFKNVLLPSQRLRDVDWYLFLKSIDDMQILELEVLVAEWHXFLRKYLEPKDFTIIQHYLEHLPKVAKERKIKSTGKVEENAANVIINAANRNFIKGSDIIYCDEDTMNVKPSFCHAAKINSFNAYKLKPLLAEAIGINLQNISGIINYATIAKFSKKVFYDSILRTDSRRMHVCINALVKVNYGDKKCVAKTLLLFEYQSNQAAKNEHFALVQFHDEISISLAGIPYCDGNRQVNMDALSESSLSKVVPLDHLASPVATLISGCELKEYHNCVYFFWPQMNRSDLQLDQAVTAFGFHTSLFDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MWJ6</accession>
    <name>A0A1C7MWJ6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">Coq5</name>
        <name evidence="4" type="ORF">A0J61_11142</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001711">
        <property type="protein sequence ID" value="OBZ80809.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MWJ6"/>
    <dbReference type="STRING" id="101091.A0A1C7MWJ6"/>
    <dbReference type="InParanoid" id="A0A1C7MWJ6"/>
    <dbReference type="OrthoDB" id="6329284at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008425">
        <property type="term" value="F:2-methoxy-6-polyprenyl-1,4-benzoquinol methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004033">
        <property type="entry name" value="UbiE/COQ5_MeTrFase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023576">
        <property type="entry name" value="UbiE/COQ5_MeTrFase_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43591:SF24">
        <property type="entry name" value="2-METHOXY-6-POLYPRENYL-1,4-BENZOQUINOL METHYLASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43591">
        <property type="entry name" value="METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01209">
        <property type="entry name" value="Ubie_methyltran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51608">
        <property type="entry name" value="SAM_MT_UBIE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01183">
        <property type="entry name" value="UBIE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 4" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="169"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OBZ80809.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="169" mass="19507" checksum="EF1C1078BAE8A4E6" modified="2016-11-30" version="1" fragment="single">MSRLIFQHTRQWSRQLPKTSIARRALFSTGVQRLDQQKTTHFGFRNVAEEEKESLVHEVFANVASKYDVMNDAMSLGIHRVWKDEFIRSMAPGPGTKLLDVAGGTGDIALRFLDYCRNIHHDQTATVKLVDINPHMLGEGEKRFQRTPYAHSKLSRERTHLEEMILTFN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MWT1</accession>
    <name>A0A1C7MWT1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_10700</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001328">
        <property type="protein sequence ID" value="OBZ81251.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MWT1"/>
    <dbReference type="STRING" id="101091.A0A1C7MWT1"/>
    <dbReference type="InParanoid" id="A0A1C7MWT1"/>
    <dbReference type="OrthoDB" id="1075553at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10492">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10492:SF57">
        <property type="entry name" value="ATP-DEPENDENT DNA HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ81251.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="296" mass="34277" checksum="9EBA055AF4DCA5A5" modified="2016-11-30" version="1">MPNTYPLYCRRMDGRSHRVQIRGKQTNEMKSVYLTNQNVVPYNPFLTEKYKAPINVELCGSVDAIKYINKYVYKGPDRTTVHLRNESDEIERYLTSRYIGPTEAVWRLFKYAMYEEDPSVTWLAIHLENEQPVYFDPEASAEEIQLIIDNTYFTLMGFFKYNTTNEDGRGSAVGRMYYCTPTAGERLFLRLLLTVVRGPTSFQDLRTVNELNQPAALWNEVCLSICDDHDVYLPKLDYGLYLLKQALIDAGKTLADFNMPQPLFDWRHLMEQIGEISSNAVFQTKSAYDGNVEEAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MWU9</accession>
    <name>A0A1C7MWU9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_10668</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001301">
        <property type="protein sequence ID" value="OBZ81283.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MWU9"/>
    <dbReference type="InParanoid" id="A0A1C7MWU9"/>
    <dbReference type="OrthoDB" id="2287442at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="141"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="397"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ81283.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="397" mass="44761" checksum="E1F6909318DB48F3" modified="2016-11-30" version="1" fragment="single">MKKKLMRGKFDHCCNDNVIILCHLLMKRATRDDGEDDDYSEGASFELFLLNEKTEAIKKKDNDKILLVDIFGSFYKKIFFMSSLTEQSHIESTLMPFIETFFNCIPSTEHLSARGQLEELPESSNLLLPICKSSSATSTSTAATTASRKRSRASSSLSSSPSWLSLFPDYLLKIVSEGEKFDVLAAEIKKPNSKSSQIVNDRVKLGNLLKLMLDRLVLAGVPSPLVCGFVDDGDVIETYKMSIEQEGRYDFVQLASFRGIRCLEDLACLPNMLNHFQQLKNIVLHMKEVIRVTRLNEVIPGPFSLSLPVPVAWLRPSLEYPALEACSKKQNTEVPGVSSLPLNETVCVVANEWKECFDRISELSASKWIKKRSRSAENLIMGEIRECHRRGQHTPTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MWV8</accession>
    <name>A0A1C7MWV8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Endonuclease/exonuclease/phosphatase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_11025</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001599">
        <property type="protein sequence ID" value="OBZ80926.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MWV8"/>
    <dbReference type="InParanoid" id="A0A1C7MWV8"/>
    <dbReference type="OrthoDB" id="2203711at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.10.10">
        <property type="entry name" value="Endonuclease/exonuclease/phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036691">
        <property type="entry name" value="Endo/exonu/phosph_ase_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56219">
        <property type="entry name" value="DNase I-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ80926.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="173" mass="19941" checksum="A8CAA453B9131ED1" modified="2016-11-30" version="1">MGDFNYSYLRLNIGTATSLEWVSTLDMHCFNALQAFDLHNPPTFRRNDTITSTIDYIFVSHSLQNVLTDATLQLINPRWSDHSLLSVQLAMSTAPTEPGLWRANPKLLGIPEYQRRLIDAIPSILDDATIRCTTPQDKWDFFKRALKRVTKNFGVNRANCRRNCLRDPQSRRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MWY2</accession>
    <name>A0A1C7MWY2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_11002</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001580">
        <property type="protein sequence ID" value="OBZ80949.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MWY2"/>
    <dbReference type="InParanoid" id="A0A1C7MWY2"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="121"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="128"/>
            <end position="156"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ80949.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="170" mass="19454" checksum="D9E4C219EC98CCBE" modified="2016-11-30" version="1">MVIEFLNDHLSKNCSQEQQQQHKIDSLETAIKKLCTNKVSPFAGEGLSDQIQADKDEDERFVRNLSKKLNSVESAISRAKPEHLALLQREQLRLLAVRKQAETHLSTPIMLCIADEAFTDGGKNNLQEEVEEEVEEEEEDEEEDEEEVVDDEEENNSEEKLALFVEAIEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MX91</accession>
    <name>A0A1C7MX91_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_10902</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001500">
        <property type="protein sequence ID" value="OBZ81049.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7MX91"/>
    <dbReference type="InParanoid" id="A0A1C7MX91"/>
    <dbReference type="OrthoDB" id="2382535at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="292"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ81049.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="292" mass="33303" checksum="BF990CB5F6B4917A" modified="2016-11-30" version="1" fragment="single">MAYQDWVKTYNGRIAKSTPPIFIPAKNNTNEPEQTLENQVPVEGVREDVQYYNECDTEEDEEAVAEIVNAMSVSEPTNVLPAPVSELDLIYSFHLTDKIPQTPFSKVLKMHNYNIPNLQVESYIQGRNKALETQDGEFRFPKTEHPTANDIECNESLIGAPYKPTGSGEFCNGRVYDYDXSREVPKLVVQKEYPYCSIAATLKKLFLRRGFADKIAEWKNRETVDDYYLDLYDAPGFSQFKTSSSNPTSFVLSDNYNLLLTLSVDWFSPFEAIYTVGCNYISIQNLSKEDGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MXT6</accession>
    <name>A0A1C7MXT6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Meiotic expression up-regulated protein 10</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">meu10_1</name>
        <name evidence="7" type="ORF">A0J61_10307</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
            <location evidence="1">Cell wall</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001113">
        <property type="protein sequence ID" value="OBZ81640.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MXT6"/>
    <dbReference type="STRING" id="101091.A0A1C7MXT6"/>
    <dbReference type="InParanoid" id="A0A1C7MXT6"/>
    <dbReference type="OrthoDB" id="536881at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009986">
        <property type="term" value="C:cell surface"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009277">
        <property type="term" value="C:fungal-type cell wall"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031505">
        <property type="term" value="P:fungal-type cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.20.20">
        <property type="entry name" value="Receptor L-domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051648">
        <property type="entry name" value="CWI-Assembly_Regulator"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036941">
        <property type="entry name" value="Rcpt_L-dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31018:SF3">
        <property type="entry name" value="RECEPTOR PROTEIN-TYROSINE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31018">
        <property type="entry name" value="SPORULATION-SPECIFIC PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0134">Cell wall</keyword>
    <keyword evidence="5" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0964">Secreted</keyword>
    <keyword evidence="4 6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008889347" evidence="6">
        <location>
            <begin position="18"/>
            <end position="376"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022512"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OBZ81640.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="376" mass="41116" checksum="8E6E391F0DBD4915" modified="2016-11-30" version="1">MLLILALSFICIQCVIAVNPCSGTLKIKSPQDLDELRLCQVFEGSIYVQNVSLGEQISLPLLQRVSGNLILEDLSDPNQIILAGLRKVDGQLKLHNNLALKRLDLTQLASAHSLEITSEPVLEAITFPSGLSQLDRLIISNTMISQMDGITANKMEEIEITNNKKLEKITLNNIEEINAIKIASNGPFASLDLSGMNYIASGEFKNLHTITGFDKIGYSGDIAFMSNSFVTLVMSNLTRMTGTLSLSDNHLLTSLSVPQLEQIGGALAMYNNNQLHQVEAPRLHTVEGAVDLSGNFTDISFPSVMNIHGGMNVQSSQEMPCDEINKLRTITQGSDFICRSNVISPQPKFTKQTSGSSISFVSIHWLYPLIAVLLIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MYG0</accession>
    <name>A0A1C7MYG0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_10099</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001031">
        <property type="protein sequence ID" value="OBZ81853.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MYG0"/>
    <dbReference type="InParanoid" id="A0A1C7MYG0"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="19"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="37"/>
            <end position="48"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ81853.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="96" mass="10332" checksum="C8F418EBF666AEF4" modified="2016-11-30" version="1">MVGLQSTKDITKDTSSTSHSLTKTDSKFNPVTPKDIQASQPASGSQSQLDFQGLPDTQESIPLSQLDSQLAAICELVSREQPTATADTDMLTFNMK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MYV3</accession>
    <name>A0A1C7MYV3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein C30D11.14c</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_10365</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001138">
        <property type="protein sequence ID" value="OBZ81586.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MYV3"/>
    <dbReference type="STRING" id="101091.A0A1C7MYV3"/>
    <dbReference type="InParanoid" id="A0A1C7MYV3"/>
    <dbReference type="OrthoDB" id="397265at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd22385">
        <property type="entry name" value="KH-I_KHDC4_rpt1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd22386">
        <property type="entry name" value="KH-I_KHDC4_rpt2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1370.10:FF:000037">
        <property type="entry name" value="KH domain protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1370.10">
        <property type="entry name" value="K Homology domain, type 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055256">
        <property type="entry name" value="KH_1_KHDC4/BBP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004087">
        <property type="entry name" value="KH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036612">
        <property type="entry name" value="KH_dom_type_1_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047890">
        <property type="entry name" value="KHDC4_KH-I_first"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047889">
        <property type="entry name" value="KHDC4_KH-I_second"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056149">
        <property type="entry name" value="PRP5/DDX46/KHDC4_KH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031121">
        <property type="entry name" value="RIK/BLOM7"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15744">
        <property type="entry name" value="BLOM7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15744:SF0">
        <property type="entry name" value="KH HOMOLOGY DOMAIN-CONTAINING PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22675">
        <property type="entry name" value="KH-I_KHDC4-BBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23469">
        <property type="entry name" value="KH_12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00322">
        <property type="entry name" value="KH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54791">
        <property type="entry name" value="Eukaryotic type KH-domain (KH-domain type I)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="K Homology" evidence="2">
        <location>
            <begin position="224"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="53"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="399"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="23"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="53"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="74"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="87"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="399"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="425"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00322"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ81586.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="425" mass="45648" checksum="06073571D4ED583E" modified="2016-11-30" version="1" fragment="single">MSESIKKRKWDQDDNGDQGPNEKIQKNEEDPSKAVSEAAARINAMLARKGIAVDDSLVNDNSSSPSDSIKSPSTTQAINNSNPASPPSSSSSATAAAAAAAAAAAAAAAAAVTASKEGEFVKDIPINDLKNRYMLTRGATQTQIQQETGADVISRGKYYPDKSLATEKEPPLYLHITASTKESLDKAIAKIEELIETAQVPQPGTGFAPREEHPRPEMKRPERKFFEKRLPVEVGGTPHFNLRAKIVGPNGAFVKHIQQETGCRVQLKGKGSGFYEASTGVESDEPLHVHLSCIREEGLEAGVKLTQDLLDTVKAEAERGPPPGQYGYGRGGGYNNSVRYNGYNNYHSYNTPAGNTTGADASGTYDYDAYNQYYSSYYAQQSAQGYQYDPNAYYNYYGYSDPNAPAATPSATNSATSTPPPPPPP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MZF2</accession>
    <name>A0A1C7MZF2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Rab-3A-interacting protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">RAB3IP_1</name>
        <name evidence="5" type="ORF">A0J61_09673</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000906">
        <property type="protein sequence ID" value="OBZ82275.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MZF2"/>
    <dbReference type="STRING" id="101091.A0A1C7MZF2"/>
    <dbReference type="InParanoid" id="A0A1C7MZF2"/>
    <dbReference type="OrthoDB" id="5560525at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051286">
        <property type="term" value="C:cell tip"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070319">
        <property type="term" value="C:Golgi to plasma membrane transport vesicle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005085">
        <property type="term" value="F:guanyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006887">
        <property type="term" value="P:exocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd21044">
        <property type="entry name" value="Rab11BD_RAB3IP_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03062">
        <property type="entry name" value="TRX_Fd_Sucrase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.910">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009737">
        <property type="entry name" value="Aim32/Apd1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040351">
        <property type="entry name" value="RAB3IL/RAB3IP/Sec2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009449">
        <property type="entry name" value="Sec2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14430">
        <property type="entry name" value="RABIN3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14430:SF0">
        <property type="entry name" value="SEC2P DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25555">
        <property type="entry name" value="RAB3A-like_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06428">
        <property type="entry name" value="Sec2p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06999">
        <property type="entry name" value="Suc_Fer-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144284">
        <property type="entry name" value="Sec2 N-terminal region"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GDP/GTP exchange factor Sec2 N-terminal" evidence="4">
        <location>
            <begin position="426"/>
            <end position="561"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="351"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="410"/>
            <end position="571"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF06428"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OBZ82275.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="873" mass="99335" checksum="69B343DE8A58CF70" modified="2016-11-30" version="1">MLYARLSFVMLIRRFFSVKQTFVGRSYSTKIPFDAKAFPFSRFEPCCPDTSVQAAENGFVPCQNHPMPAVLGKKIDMVDSMQRPASLRHIVGCVGHDAIEWTRAKVEAVPDGAVQTLLTAENEWLRHNRSLHDSSNVLITVADRPSVDPQAPDLLFFPEFKMLKHVNAITQGSPIYTVMDSIWRDPHQPLDEISELEEIKADTVVLVCTHGRRDLRCGKLGPLIVEEFKHWIEKAGYNDKVEVWGTSHFGGHKFAGNLIIHQRGLGGHMYGNVRQCHVKDIVDRHIIHSKVIKEIWRGQVTPPLVQKKYVSIQLKAMASTTEQDSSVITDKAIHLYNSLKAAIEKPTINPEAIQLPLPPSPSTSTSSVQSIKQRNEDDDDDDDDCPCQHILGSGQEITMCSLCQSPIPIIEALLAEKDSYESEILELQAQLEIEQKRISEQLTCIDQLNSRLEQVVLELNTKTTEFEALQSDMELLNDKYVDEIERVAEIQHSKDMVESELEDLSRRLFEEANGMVAHEKREKHNLEIAQKHLENQLKETKERLGAEQMQLKELRKRMEDMALESEHLANETFSTTETPLKQDGTSLSTSDQAQNAARLFDERTRLLSEDQKRVNAIDTMVLSEFEEFVKTGTSVPLKKLHTIPFMKNCQEEDVEACLRFGPNSRLSARKINEAIVLNTCFIEEAPPGFAQEQAKRIMSEMPLKISGAKSMMWERFSSNHLTTVFSGCQACGRNDGTTLPYRFRISYFDDWACIDRFCRDRLVAVCEFYVLIRNIRQGLYSNRTILDLYQEAMRLRLQMFYARMGALPWTLRTTAAANKKQIKVISSESSPLPKSIKTIQDVRRGSLNEIISNKKSNLTYATTALKQDKETEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MZJ9</accession>
    <name>A0A1C7MZJ9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Phospholipase B1, membrane-associated</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">Plb1</name>
        <name evidence="2" type="ORF">A0J61_10095</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001030">
        <property type="protein sequence ID" value="OBZ81856.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MZJ9"/>
    <dbReference type="STRING" id="101091.A0A1C7MZJ9"/>
    <dbReference type="InParanoid" id="A0A1C7MZJ9"/>
    <dbReference type="OrthoDB" id="10265800at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004620">
        <property type="term" value="F:phospholipase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006644">
        <property type="term" value="P:phospholipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1110">
        <property type="entry name" value="SGNH hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001087">
        <property type="entry name" value="GDSL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038885">
        <property type="entry name" value="PLB1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036514">
        <property type="entry name" value="SGNH_hydro_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21325:SF31">
        <property type="entry name" value="GH22081P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21325">
        <property type="entry name" value="PHOSPHOLIPASE B, PLB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00657">
        <property type="entry name" value="Lipase_GDSL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52266">
        <property type="entry name" value="SGNH hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="59"/>
            <end position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ81856.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="456" mass="51052" checksum="E2704A1D48DCA949" modified="2016-11-30" version="1">MFYVKGKSFVASFSKTSHLLPKDQQEANLTQPTDYQDQSNLYTASAYHHFEGFADMLPLFGFVSLAMMIMTYLFILPFTPLVLTATIAHRQNTTNPQVGIEVPLDIGCPFLAPRTSPAKSVHDLRPDDIRIVAGIGDSVMAGFGAKGIQRTFFNLENLYENRGVSFAIGGDPGAVTMPNILNYYAHHLNGSSVGEHLISICFDGMLGNQMCPQGQYRPKIDRLNAAQSGARSLNLDHEIDYLLDQLEDLYDTGEVEPTDWKLLTVFIGSNDICHSCTEFTSLPTPFGVNVMAAIDRLKKSMTHVLIQIIGIMRVQDIVVATSNYTDYCRPIRGSSFVGHDHMCECSHSVTNRTLMASLFPQYNSVLQGVTSHYQTSGEDDNFTVVFQPLLIDILSFPIEAISNIDCFHPSVLAHEWMSKMLWNMMFMLPDQKQETLLYDPKAPIYCPTENDRIQTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MZT1</accession>
    <name>A0A1C7MZT1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_09593</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000886">
        <property type="protein sequence ID" value="OBZ82357.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MZT1"/>
    <dbReference type="InParanoid" id="A0A1C7MZT1"/>
    <dbReference type="OrthoDB" id="2230015at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ82357.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="552" mass="64068" checksum="EF3303BD9CEE8A53" modified="2016-11-30" version="1">MLLHFPAEIVNRVSSYLSHEDFYHLVLANQACYYQFTPFLYQKMSFKDGDQFKQFSNELKHFHPHVRNLHLPYFSKIMRILPQFPLVFPSLDSINLTVSDARCPPQFCEPFRNLRALTMKTFGLPASSIEIIAAMPYLTHLDITLLANAKITVNLLNDLHLLCPLLQCLYINGSFKDSFTEKTESQPVQIVNKLKSLHLESTSSLYEYHFWLKHIAVTYPNLETLGLGQQTVKIENHYSSEFYDWFRSSCPHVVQFKWLNIVPDDNFLKKLDQQQRQLQELRLNDATLVKHLLMEVEPSDDAYLSTIFNLDIRISIDTTYNTLLSSLGRVCYRLEQLAVEQYDSHSPDELYMDTVLDLLPRLTSVSFTQIRIGIQSRKADFDSHPLEKIKLKGCYVPYDTFDSIGFRCPYLSNLSLDQTSHSNHLVKIHLPYQKLNKVELNSIYLSKLDLDAVVQLFRLKQSNRSDWYLMDSYKKPAYSRTIIAKSFKKLNTAVSYLSYSSQKLESQSDNHTNSLLPYALRDPDLRNAAKDGYVDFVCQSVCSLYINSKKVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N0W3</accession>
    <name>A0A1C7N0W3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Survival of motor neuron-related-splicing factor 30</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">smndc1</name>
        <name evidence="5" type="ORF">A0J61_09644</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000898">
        <property type="protein sequence ID" value="OBZ82306.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N0W3"/>
    <dbReference type="STRING" id="101091.A0A1C7N0W3"/>
    <dbReference type="InParanoid" id="A0A1C7N0W3"/>
    <dbReference type="OrthoDB" id="79171at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="CDD" id="cd21182">
        <property type="entry name" value="Tudor_SMN_SPF30-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002999">
        <property type="entry name" value="Tudor"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46297">
        <property type="entry name" value="ZINC FINGER CCCH-TYPE WITH G PATCH DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00333">
        <property type="entry name" value="TUDOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63748">
        <property type="entry name" value="Tudor/PWWP/MBT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50304">
        <property type="entry name" value="TUDOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tudor" evidence="4">
        <location>
            <begin position="91"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="50"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="156"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="216"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="176"/>
            <end position="189"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OBZ82306.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="276" mass="29866" checksum="023206E5C440247C" modified="2016-11-30" version="1">MSAEEIESYKFQLEQVELALQADPENDELQKLQNDLKELIAMFEAVTPTTPATPTVTSAGTQDSPAPKNKRKYDSEPTPPSTSTTALKLHEFSVDQEVLARWSGDGQFYKAIITAIGGADQVFSVKFKGYNDVEFVKAEDIKPIVDKKRPGIFEDVVDSSSKRKKKEAAPQATNASSSSSLGGHNNHSLPPTPAASLKKKKASEFESKKNAWLNFATGSSSSSKKKKTVAPVINKKSIFKTPDNPEGKVGVVGSGKGMTSFQQRGKHVYAPTGAEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N132</accession>
    <name>A0A1C7N132_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">ATP-dependent DNA helicase</fullName>
            <ecNumber evidence="1">5.6.2.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_10887</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="5.6.2.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the helicase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.6.2.3" evidence="1"/>
    <dbReference type="EMBL" id="LUGH01001483">
        <property type="protein sequence ID" value="OBZ81064.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N132"/>
    <dbReference type="STRING" id="101091.A0A1C7N132"/>
    <dbReference type="InParanoid" id="A0A1C7N132"/>
    <dbReference type="OrthoDB" id="1075553at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043139">
        <property type="term" value="F:5'-3' DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000723">
        <property type="term" value="P:telomere maintenance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010285">
        <property type="entry name" value="DNA_helicase_pif1-like_DEAD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10492">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10492:SF57">
        <property type="entry name" value="ATP-DEPENDENT DNA HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05970">
        <property type="entry name" value="PIF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0227">DNA damage</keyword>
    <keyword evidence="1" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="1" id="KW-0234">DNA repair</keyword>
    <keyword evidence="1" id="KW-0347">Helicase</keyword>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA helicase Pif1-like DEAD-box helicase" evidence="2">
        <location>
            <begin position="418"/>
            <end position="581"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="581"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU363044"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF05970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ81064.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="581" mass="66505" checksum="31AA1EB41915F30F" modified="2016-11-30" version="1" fragment="single">TVWCSDTPPCAVVPNAYPLAYETVTKHIVYGSCGILNSNAVCMDAEKECTKWYPQEILRRNNGSSIPKIINEHTYNIDNCWIVPHNLYLCSKYDAHINGELCSSINSVKYVYKYVYKGHDRASMSVEQKDEIKSFVDARYVSASELCWRLFSFPIHKEFPSHQRLAIHLEGEEPVYFNEDDDIFNGLQRACTQETTLTSWFKTNASDPNARSILYVWHDEKEPRRWEKRVRGFGGTIGRIYAVSSKQTELYHMRMLLHHVSGATSFAHLKTVNGIIYPTFQDACRAFHLRESDDQWSQRLDEAAQIQAPVSLRRLFTILLIFRTPSNPYQLWLEFRNELSEDYLHQLRNVPNNALFNIDDILATQHGTCLICYPGFVLPTIDTRSHYGNAGVCRLIREQYRLHMFAQQSSVSEDVAGLNNDQRQVFDVIMRCVERDSYQSTEHIKIFFVDGPRGAGKTYLFNIILKAVRSANDGYALAVVFSATAALLLEDGRTAHSISKIPLEASSTTFCDNKPQFPTAELLKKTKLIIWVESSMINKSILETVDRTFKDIFSRINEALSNVSFGGRLMLFGGNFRQVLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N1E7</accession>
    <name>A0A1C7N1E7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">chitin synthase</fullName>
            <ecNumber evidence="2">2.4.1.16</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="primary">CHS8_8</name>
        <name evidence="17" type="ORF">A0J61_09500</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="12">Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.16" evidence="2"/>
    <dbReference type="EMBL" id="LUGH01000864">
        <property type="protein sequence ID" value="OBZ82449.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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        <property type="term" value="C:cell septum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016459">
        <property type="term" value="C:myosin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003779">
        <property type="term" value="F:actin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004100">
        <property type="term" value="F:chitin synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003774">
        <property type="term" value="F:cytoskeletal motor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006031">
        <property type="term" value="P:chitin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031505">
        <property type="term" value="P:fungal-type cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.530">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.120.10">
        <property type="entry name" value="Cytochrome b5-like heme/steroid binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.850.10">
        <property type="entry name" value="Kinesin motor domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.720">
        <property type="entry name" value="Myosin VI head, motor domain, U50 subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="entry name" value="Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004835">
        <property type="entry name" value="Chitin_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001199">
        <property type="entry name" value="Cyt_B5-like_heme/steroid-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036400">
        <property type="entry name" value="Cyt_B5-like_heme/steroid_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036961">
        <property type="entry name" value="Kinesin_motor_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001609">
        <property type="entry name" value="Myosin_head_motor_dom-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22914">
        <property type="entry name" value="CHITIN SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22914:SF13">
        <property type="entry name" value="CHITIN SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03142">
        <property type="entry name" value="Chitin_synth_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00173">
        <property type="entry name" value="Cyt-b5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00063">
        <property type="entry name" value="Myosin_head"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01117">
        <property type="entry name" value="Cyt-b5"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00242">
        <property type="entry name" value="MYSc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55856">
        <property type="entry name" value="Cytochrome b5-like heme/steroid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50255">
        <property type="entry name" value="CYTOCHROME_B5_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51456">
        <property type="entry name" value="MYOSIN_MOTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-0009">Actin-binding</keyword>
    <keyword evidence="12" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="11" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="4" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="9 14" id="KW-0472">Membrane</keyword>
    <keyword evidence="10 12" id="KW-0505">Motor protein</keyword>
    <keyword evidence="8 12" id="KW-0518">Myosin</keyword>
    <keyword evidence="12" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="6 14" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 14" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="890"/>
            <end position="907"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="928"/>
            <end position="950"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="1192"/>
            <end position="1214"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="1590"/>
            <end position="1608"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="1620"/>
            <end position="1638"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="1645"/>
            <end position="1668"/>
        </location>
    </feature>
    <feature type="domain" description="Myosin motor" evidence="16">
        <location>
            <begin position="1"/>
            <end position="519"/>
        </location>
    </feature>
    <feature type="domain" description="Cytochrome b5 heme-binding" evidence="15">
        <location>
            <begin position="955"/>
            <end position="1015"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="228"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="562"/>
            <end position="589"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="834"/>
            <end position="858"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="228"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="562"/>
            <end position="580"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="835"/>
            <end position="856"/>
        </location>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <begin position="51"/>
            <end position="58"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="non-terminal residue" evidence="17">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012543"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
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            <dbReference type="ARBA" id="ARBA00022679"/>
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    </evidence>
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        </source>
    </evidence>
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            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS51456"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="OBZ82449.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="1793" mass="204788" checksum="AB87551EB41888FC" modified="2016-11-30" version="1" fragment="single">DATLKAYGQYGYKDVSPHKYGSPEPHVYEMATRAYLLVRRRSENQAVVLSGMTGSGKSTTHYHLLKEILYLSTHDRKDEKMQRQILGAHAILRSFSVAASTHNETSSCLSQTQTLQFNNKGRIVGSTISVFLLNAHRISQSNLQQYDIFYQLVAGTTPDEKQALQITHSNFNYLKQQRDTQQDSLNFEELKIMLQSCGFKPITIAQMCQLLAAILHLGNVQFADNTRRAQTGGSTPRISSAGNGDSNTTRESCRIRNKELLNLVAGALGVATSRLETTLTHKLKLIDNEFCTAFLTKETAIKQRDSLAHALYAALVLWITNAFNQKLNAENVLEDADEGKNAIKTINIIDIEGFNLSITMQNTGRFHDICVNYVNEQLRSYLFDRRVNANASANVECSKDGAWRYSLSTKIKAPNQSLNFFDGTESNQVGFINLLNQVSDQFERHEANATDNSLLSKLFQQKAESQTDGNYAVFDDASSNASSFKIQHFNRTTEIDYSIDGFIESNISAVSPEFIDLFRHNCTNEFVQELFEADSLVGWVTDTHSRDKETVIKAQLPVWTGSKDKTKKEESSSEKSESNKQGRLKRGKKLIKPTSNTRTAISQIADGVKLLKQKLDSSMVMEIIHICPNNMQKPDFFDLDFVRHQIKILQITEIASQLVHVDTMLGYTPKSFVQFYRPLIADSLPRFNFDELFEDEEEDEYEQASALKECISQWAEAMDWSDRQMIFGHRNIWLDFSLWRILENQIRSFEKGKRSKNKLITVPSTTDLEQDLATEGHATPRQPTVHSRATTSEYGMLSYGHTSYGRSSWYKESSGYDHDFSDMTLEDFSDITSYTDHHQNNNEEKREENGSKKMDEGFGPNMDMSKMMKNYSVEAEEHIEEVTITRLRKWWSRFVWLMTWWVPTFMLSYMGNMKRQDVQMAWREKLTLCLLIFGFSATIIFFIVGLSPVVCPGTKTLYSPEDVFNHQAMDNYWVSVRGKVYDVTSFVATEHGTPVHLGTKTNMYSLAGLDLSYTFPPPLSVACTGLVTDPQLTIFPNETIQLGPFIHVSGPQQQEAGLDKLKDPYWLNKYFGSTMSLYRKGDIVISMKQIKEDYIGWGRLIASIDDKVYDITDYMNTARRFPLDVPGVPEYHFLDPSVEALFTKFGGKDVTVEWNKYSQAMNEETRRRNKACLDNVFYIGRVDYRETLRCTFINYLLLSFAIIMSVVILVKFLAALQFGGSPTPDEHDRFVICQVPCYTEDEDSLRKTIDSLAGMTYNDKYKLLFLIADGMIIGSGNSKPTPRILLDILKHDEDDDPEALMFKSIGEGSKRLNYGKVYSGLYEYEGHTVPYIVVVKVGKSNENVKPGNRGKRDSQIICMSFLNKVHFDSEMSPLELEIYYQMKHVIGVDPSLYEYILMVDSDTEVYPDSLNRLISCMLHDSRIIGLCGETELGNEDRSWITMIQVYEYYISHHLVKSFESLFGSVTCLPGCFCMYRIRTATSQQPLIVSNSVIQNYSDNVVDTLHKKNLLHLGEDRYLTTLMMKTFPQYKMMFTPHAKCKTVAPDKWRVLLSQRRRWINSTIHNLLELILLHELCGFCCLSMRFVVLTDLIGTITLPSSVIYLVYLMYEVITGSGPIPTIALGMLAGAYGLQSLIFVIKRQWQHIGWMIIYIFAIPIFSFFIPLYAFWHFDDFSWGNTRVVVGDNKKQIIVSDEEKFDESIIPLKKWSVYEQELSETKTATYQTRNSLQVSKIPKLNSQQLLPTQRMRVVNSTKNFVPSRFRCSFDVDSGTNGILGFFQGKLAFVSEKTFPLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N2A4</accession>
    <name>A0A1C7N2A4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 6">DNA polymerase alpha subunit B</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">pol12</name>
        <name evidence="9" type="ORF">A0J61_08688</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Accessory subunit of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which plays an essential role in the initiation of DNA synthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the DNA polymerase alpha subunit B family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000693">
        <property type="protein sequence ID" value="OBZ83265.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N2A4"/>
    <dbReference type="FunCoup" id="A0A1C7N2A4">
        <property type="interactions" value="183"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N2A4"/>
    <dbReference type="InParanoid" id="A0A1C7N2A4"/>
    <dbReference type="OrthoDB" id="336885at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005658">
        <property type="term" value="C:alpha DNA polymerase:primase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006270">
        <property type="term" value="P:DNA replication initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.60">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.530">
        <property type="entry name" value="DNA polymerase alpha-primase, subunit B, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007185">
        <property type="entry name" value="DNA_pol_a/d/e_bsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043034">
        <property type="entry name" value="DNA_pol_alpha_B_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016722">
        <property type="entry name" value="DNA_pol_alpha_bsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054300">
        <property type="entry name" value="OB_DPOA2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23061">
        <property type="entry name" value="DNA POLYMERASE 2 ALPHA 70 KDA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23061:SF12">
        <property type="entry name" value="DNA POLYMERASE ALPHA SUBUNIT B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04042">
        <property type="entry name" value="DNA_pol_E_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22062">
        <property type="entry name" value="OB_DPOA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF018300">
        <property type="entry name" value="DNA_pol_alph_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0235">DNA replication</keyword>
    <keyword evidence="5 6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA polymerase alpha subunit B OB" evidence="8">
        <location>
            <begin position="200"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="domain" description="DNA polymerase alpha/delta/epsilon subunit B" evidence="7">
        <location>
            <begin position="330"/>
            <end position="536"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007299"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00018596"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRNR" id="PIRNR018300"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF04042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF22062"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OBZ83265.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="579" mass="65854" checksum="62440640CFB887F8" modified="2016-11-30" version="1">MEAEVVRVFELNIPQEKDVAKELSELCSVYSITPDNLKFKWEAFALNSGCSIKPTIPYIKHLRNSLKREFDRSVKARKTTTGKVVTKRTQGFDLSDYGIAQTKQEDSVDDFMSSMLGSMAPKHHKVIPTPTTQVSDTQISSVSSQFLTRKAAHMIESQYHPELPLIEKTNEALPEIHFSHLQYPVQEYRYMFEKIKERADTLDERIEYIGSLIAAAHQVPLESFSNPTRPNQESIYTYGRICSDVQSESEGRLNERSVMLQTSKELGMGRRVKLDLAGLDRYSLFPGQIVGLYGRNALGDVFFVERLLMPPMPEKYQLTSVQHSRPLEMIVAAGPFTLNDDLSFQPLEDMLQMCATQKPDVVLLMGPFISSQHPRLLSGKIETLPEQLFVEQIGRRLEQLVESLPQTHVLLMPHQDDIIHMYPLFPQPAFPDLIKHQRIHMLSNPSAIGINDHTIAVGHVDILFRLAREEISRNPHGAQVDRMQTLVQHVLEQHTFYPLFPHAIGDSIDSSQLHHIQLSRKPDLLILPSQLKHFTKDVQGTVCINPGHLCKGLSSGTYARVTMYPKNENSNMRVDLFKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N2B8</accession>
    <name>A0A1C7N2B8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">RNA helicase</fullName>
            <ecNumber evidence="2">3.6.4.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">DHX35</name>
        <name evidence="10" type="ORF">A0J61_08700</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.13"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the DEAD box helicase family. DEAH subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.13" evidence="2"/>
    <dbReference type="EMBL" id="LUGH01000695">
        <property type="protein sequence ID" value="OBZ83250.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N2B8"/>
    <dbReference type="STRING" id="101091.A0A1C7N2B8"/>
    <dbReference type="InParanoid" id="A0A1C7N2B8"/>
    <dbReference type="OrthoDB" id="10253254at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071013">
        <property type="term" value="C:catalytic step 2 spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd18791">
        <property type="entry name" value="SF2_C_RHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000578">
        <property type="entry name" value="probable ATP-dependent RNA helicase DHX35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000767">
        <property type="entry name" value="Putative ATP-dependent RNA helicase DHX35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1080">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011709">
        <property type="entry name" value="DEAD-box_helicase_OB_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002464">
        <property type="entry name" value="DNA/RNA_helicase_DEAH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048333">
        <property type="entry name" value="HA2_WH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007502">
        <property type="entry name" value="Helicase-assoc_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18934">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18934:SF136">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE DHX35-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21010">
        <property type="entry name" value="HA2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07717">
        <property type="entry name" value="OB_NTP_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04408">
        <property type="entry name" value="WHD_HA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00847">
        <property type="entry name" value="HA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00690">
        <property type="entry name" value="DEAH_ATP_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 10" id="KW-0347">Helicase</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="8">
        <location>
            <begin position="57"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="9">
        <location>
            <begin position="252"/>
            <end position="428"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OBZ83250.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="694" mass="78670" checksum="DE13603C6896751F" modified="2016-11-30" version="1">MSFWKPGTLVPGSSLDRDTENESSKAIVAHAEKQHRHLTLKQQRDRLPVFKLRRELLYLLETFQTVVIVGQTGCGKTTQIPQYLYESGWSGNGKQIACTQPRRIAATSVAQRVAEEMNCELGAEVGYLIRFDDKTSEKTKIKYMTDGMLFRETMIDPLLSNYSVVMIDEAHERSLYTDVLIGVLKKVQKKRKDLKVIISSATMDAEQFYQFFNANTNQDKTQDTATIISLEGRMYPVDTFYVDKPVADYLETCIQIVFDIHLKEPVGDILIFLTGREEIDRVVEEVYDRGKTLPKNSLAIMPLPLYAGLTVEEQLQVFEPTPKYTRKVIVSTNIAEASVTLEGVVYVIDSGFVKMRAYNPKTGMEALVVTPISKASALQRAGRAGRVKPGKAYRLYTEETYRQLKDTSTPEIQRSNLATIILQLKALGIDNVLRFDFITPPPAELMTRALELLYSLKALDDVGRLTIPMGMQLAELPLDPMLAKILLASKEFGCSHEIVTIAAMTSVQNIFIQPNKVPREIIYEARRKFWVEEGDTLSLINVYNAFINKGNKSAKWCHDRFLNFKALSRAMAIRLQLIKYLKRFDIPLVSATSKYPATADGRLAASRDVRKCITTGYFSQAAIAEPDSSGRFRTVRDNVLLQIHPNSVLFNRTPKCVVFHEVVETTQAYMRDLTVIEPKWLAELAPHFYEYKTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N2J8</accession>
    <name>A0A1C7N2J8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Oxysterol-binding protein-related protein 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">Osbpl3</name>
        <name evidence="7" type="ORF">A0J61_09105</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the OSBP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000774">
        <property type="protein sequence ID" value="OBZ82849.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N2J8"/>
    <dbReference type="FunCoup" id="A0A1C7N2J8">
        <property type="interactions" value="168"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N2J8"/>
    <dbReference type="InParanoid" id="A0A1C7N2J8"/>
    <dbReference type="OrthoDB" id="1854502at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032541">
        <property type="term" value="C:cortical endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097038">
        <property type="term" value="C:perinuclear endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032934">
        <property type="term" value="F:sterol binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006897">
        <property type="term" value="P:endocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035621">
        <property type="term" value="P:ER to Golgi ceramide transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006887">
        <property type="term" value="P:exocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0120009">
        <property type="term" value="P:intermembrane lipid transfer"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030011">
        <property type="term" value="P:maintenance of cell polarity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034727">
        <property type="term" value="P:piecemeal microautophagy of the nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.160.120:FF:000001">
        <property type="entry name" value="Oxysterol-binding protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.160.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.680">
        <property type="entry name" value="GOLD domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009038">
        <property type="entry name" value="GOLD_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036598">
        <property type="entry name" value="GOLD_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037239">
        <property type="entry name" value="OSBP_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000648">
        <property type="entry name" value="Oxysterol-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041680">
        <property type="entry name" value="PH_8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001849">
        <property type="entry name" value="PH_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10972:SF203">
        <property type="entry name" value="OXYSTEROL-BINDING PROTEIN HOMOLOG 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10972">
        <property type="entry name" value="OXYSTEROL-BINDING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01237">
        <property type="entry name" value="Oxysterol_BP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15409">
        <property type="entry name" value="PH_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00233">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144000">
        <property type="entry name" value="Oxysterol-binding protein-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101576">
        <property type="entry name" value="Supernatant protein factor (SPF), C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50866">
        <property type="entry name" value="GOLD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50003">
        <property type="entry name" value="PH_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0445">Lipid transport</keyword>
    <keyword evidence="4" id="KW-0446">Lipid-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="domain" description="GOLD" evidence="6">
        <location>
            <begin position="1"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="domain" description="PH" evidence="5">
        <location>
            <begin position="210"/>
            <end position="302"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50866"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OBZ82849.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="965" mass="110083" checksum="64D0330213BEE636" modified="2016-11-30" version="1">MPEVHVQPRSIYEHHIQVKRPNTTLKWSFSTKKNSICFGLYFKPDQTHSSHYTSISSLNKSINRNLSLPKLTQARYHSIIVRNLPEYSTPLSPTATKSNTHSDNEDELYSHQNGTLNMVNQSLLQFNHFTTRRKSSSATSVSNLLENDFIELIPIEQVNSSKETVNGSFLAERSGNYVLLFDNMFSRTTPKLLFFTVATDEPLYEDLSVDVDMSGWLLKKRRKRMQGWAKRWFELSSTGVLSYSVSKGAIKRGSLQVGLSTIVISAKHRTIHLDSGTTTFHIKAPSVELLEQWLTCIHARRSACLSANQNPIIWDTDEAGFESVAGFVPELMPNVNDNQPQKQRNEENYLIVSKSLSDIDMHIVQLKQLLFGDSSSILLNETSIHPNSEITFEEHKKQSANATSVGHSNDNHIHVSFIQALINAQLDETQAYPSTVTSHQKSLINAISTSLQSIKNCRDTISNAYHEMQQLNQDECDDMAFNSLQVSNRTQSNLLSHRSVKSLYSHSMLSDKYFDAEDYFMSSDENESIHDFVGVDSEEEGEDENEGYISLPPAIDKHSDTSDDNSDALVVQRRDRLPHPVAVKSVSFLGVLRKNVGKDLSTISMPIIFNEPINLLQHLCEELEYSDLIEKAAHQASSVDRLMYIAIFAISGYASSQYRIGRKPFNPLLFETYECVRPDKGFRFVSEKVSHHPNILACYAEAKLYEYSQSCSGKTKFWGKSMELISEGQCCIKLKGHNDVFTYSKPSSWLRNLVAGTKYIEHIGEMKVINHTTGDYAIVTFKEATQAGTGFFANLAFDNSQYRNHVAVKLYNQSNSLIKELQGKWNESMSEVVGPDQYSTLWRCKSPSISNHDDYYGFSSFLMELNEITIIEENKIPITDTRYRPDQRLFEEGKVFEAESEKERVEQLQRERRKQSELSGEQCQPLWFELKEDSLSPKGQTWQYKGGYWEARNKNQWPSEMVKLW</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N2S4</accession>
    <name>A0A1C7N2S4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Condensin complex subunit 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">cnd3</name>
        <name evidence="10" type="ORF">A0J61_08641</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Chromosome</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the CND3 (condensin subunit 3) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000685">
        <property type="protein sequence ID" value="OBZ83308.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N2S4"/>
    <dbReference type="FunCoup" id="A0A1C7N2S4">
        <property type="interactions" value="332"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N2S4"/>
    <dbReference type="InParanoid" id="A0A1C7N2S4"/>
    <dbReference type="OrthoDB" id="27187at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000793">
        <property type="term" value="C:condensed chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000796">
        <property type="term" value="C:condensin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007076">
        <property type="term" value="P:mitotic chromosome condensation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027165">
        <property type="entry name" value="CND3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025977">
        <property type="entry name" value="Cnd3_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14418:SF5">
        <property type="entry name" value="CONDENSIN COMPLEX SUBUNIT 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14418">
        <property type="entry name" value="CONDENSIN COMPLEX SUBUNIT 3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12719">
        <property type="entry name" value="Cnd3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="4" id="KW-0132">Cell division</keyword>
    <keyword evidence="3" id="KW-0158">Chromosome</keyword>
    <keyword evidence="6" id="KW-0226">DNA condensation</keyword>
    <keyword evidence="5" id="KW-0498">Mitosis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nuclear condensin complex subunit 3 C-terminal" evidence="9">
        <location>
            <begin position="618"/>
            <end position="903"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="123"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="578"/>
            <end position="605"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="948"/>
            <end position="1050"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="123"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="150"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="165"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="596"/>
            <end position="605"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="948"/>
            <end position="959"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="960"/>
            <end position="970"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="987"/>
            <end position="1000"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="1008"/>
            <end position="1050"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023067"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF12719"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OBZ83308.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="1050" mass="121467" checksum="6487448B83AB83F8" modified="2016-11-30" version="1">MVRRKNTVDPNVIEKSTMEKATALANLQSLMSDIFDDAQKQDANLRADAIKLRDLQMACCLNAPRKIGEPEDIDFEGEDRFLKMVHKMVNLVIKTKKREPTADRVQRFIAGFLQYIQSKDEEAKQKAREKETTTTAATEDVDMEEATQPDIPQSESTKTTQSQNVEEEEEEGEYETVTSRFVESLLRHLFKGFLDSKAIIRTRCCQIIALSISSMGELDEDLYQDLKSHLFESHLDKDANVRAQAVTALCRLQSDNEVNPSDGQTILDKLMWSVRHDPSAEVRRLILFNIDVTQETIPYLVKSIRDPDDTNRRVVYLKPLSDLSNFTILSFEERLQILQWGLNDRAELVRKAALKMFSERWIAHASNNLIEFLERLEATRPAVSPLVEKLLKVFFKDRMDIVNEINFDAVLDEFWNNLSGESALLAKAVIEFLQSQDGLDERLDDILPEVTRHVFNLENYYNLYRAHVNTEDAGMTNYEFVLTQLLDISLCLDYADEVGRRKMFEFLRHVLKSEELLDDHLERVIKIFRMISIDERDFTRSIIEIISDIQEEAEGEEEQFEDGPTKRTRLTETAMAIRANSSSPSLKNSDEEAEEKDGTQEPEKLQPHVQDNLVVQFRCLSICKRMLENSYEPLTDNSSLYGLLNDLIVPAVQNADTLLRQEGLHCLGLCCTLDKRLAQHNITLFITCIKHGHEDLVKKAVRTLGDVLLMYGVDTMVEYLSSPNDVREVFEFGLDHDNTEIQSLTTQALCKLMLFNRFDDNELLRLMVLLYFFPQTEIDEASNTIHQCLAYFFPAYCYSSAAHQKAISNITIPALEELCHVYSDLAADETMTNPKNISDMLADWNDPEKLANARSKQSNFIESDQDSVFQVPGTLAVQALKVILNESEDLRRKTLCHFVLRLRLDKISYQQMKEIRDLIRKIDKKRPIKVMPTRRAFEKIANRFDSILTQEGQQDIQTTLEDEDEEEEPREEVSRTNLRSRKRGRDEDEISEEESEEEEDYEKKDRNDDDNDEEEGDEDEDEDEDEDEEEDEDQEDDEDQESEEEEESDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N3W1</accession>
    <name>A0A1C7N3W1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_08198</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000609">
        <property type="protein sequence ID" value="OBZ83751.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N3W1"/>
    <dbReference type="STRING" id="101091.A0A1C7N3W1"/>
    <dbReference type="InParanoid" id="A0A1C7N3W1"/>
    <dbReference type="OrthoDB" id="2281765at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="28"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="109"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="181"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="402"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="28"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="43"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="234"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="406"/>
            <end position="434"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ83751.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="434" mass="48677" checksum="30ECF04F6C0762E2" modified="2016-11-30" version="1">MRSQDKMRNLIGQNSILKTYVIITPTTTSTTTAESHTASTPPVDTTPTASFQLHRNKRRRRSSLSSPCPEQLSPTLDMPASKSKIAKPTAPKIPSVLTRNTFSQLAVSQRSDDLPATQLPPVPPTTPIDLHSYPQLPDFLLAMQQQLRRHEAKFLEFETLLAENTTLKKELHAAQSRIRELEAAQSDRPAPVASNSSPEIQRGTEASRYATVAASHTSFPPLPRPSTTRAQGQRLPRPARASPAAREAVSRTFSRTSDSQGFSFIYLHCRGKEPISKMREKLRILKLQSSRLIDIHYPSNHVMAILLHNDYLEEATNLLTLNQIELLTFDPTSLEHLNDPKYTDLTPEQRSSEACEIYQQRLCHMITRIRNEHRQIAVARSFRKQAWITEDQFTNIVHTIRPPTQKPTISTSTAMQLDSNDTSPADGSTSAHSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N3Z2</accession>
    <name>A0A1C7N3Z2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">START domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_08105</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000595">
        <property type="protein sequence ID" value="OBZ83842.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N3Z2"/>
    <dbReference type="STRING" id="101091.A0A1C7N3Z2"/>
    <dbReference type="InParanoid" id="A0A1C7N3Z2"/>
    <dbReference type="OrthoDB" id="196858at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008289">
        <property type="term" value="F:lipid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00177">
        <property type="entry name" value="START"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.530.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023393">
        <property type="entry name" value="START-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002913">
        <property type="entry name" value="START_lipid-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051213">
        <property type="entry name" value="START_lipid_transfer"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19308">
        <property type="entry name" value="PHOSPHATIDYLCHOLINE TRANSFER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19308:SF14">
        <property type="entry name" value="START DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01852">
        <property type="entry name" value="START"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55961">
        <property type="entry name" value="Bet v1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50848">
        <property type="entry name" value="START"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="START" evidence="1">
        <location>
            <begin position="10"/>
            <end position="187"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50848"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ83842.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="292" mass="32292" checksum="7F244F8EA6B4DE12" modified="2016-11-30" version="1">MTVTNPHAEASKQAMNLLKQYASSVEGWNMTQEKEGVKLYSKQVDSSSIPLVRGDTLLAGHQFTAQQVATVATLPGCRKMWDEKYDSSEIKTMYSRYESLFWVKMKAPWPVSPRDICATSYREVSEDECHIAMVSVEDNTVPPLSGCVRANLMLSGWKIVKVEAGIAVTYITQVDLAGAIPSSFLKSIQQQVPMCAGSVVKYIQDHGYAPTTSECTAEFKLETFEHSKKEYVAQLDGIGNATWLISKRMYPSGFKVSLDGKGTKQTTDHHHGDQLLTVTDINGPLTVKINKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N4E4</accession>
    <name>A0A1C7N4E4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Gem-associated protein 5</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">GEMIN5</name>
        <name evidence="6" type="ORF">A0J61_07977</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000575">
        <property type="protein sequence ID" value="OBZ83973.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N4E4"/>
    <dbReference type="STRING" id="101091.A0A1C7N4E4"/>
    <dbReference type="InParanoid" id="A0A1C7N4E4"/>
    <dbReference type="OrthoDB" id="7326421at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032797">
        <property type="term" value="C:SMN complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003730">
        <property type="term" value="F:mRNA 3'-UTR binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000387">
        <property type="term" value="P:spliceosomal snRNP assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.470">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052640">
        <property type="entry name" value="Gemin-5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056421">
        <property type="entry name" value="TPR_GEMI5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46362">
        <property type="entry name" value="GEM-ASSOCIATED PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46362:SF1">
        <property type="entry name" value="GEM-ASSOCIATED PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23774">
        <property type="entry name" value="TPR_GEMI5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101908">
        <property type="entry name" value="Putative isomerase YbhE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="290"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="614"/>
            <end position="657"/>
        </location>
    </feature>
    <feature type="domain" description="Gem-associated protein 5 TPR" evidence="5">
        <location>
            <begin position="903"/>
            <end position="1056"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="720"/>
            <end position="770"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="729"/>
            <end position="743"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="749"/>
            <end position="758"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF23774"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OBZ83973.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="1073" mass="123615" checksum="37C18A7C94AE3419" modified="2016-11-30" version="1">MNMLERFPKHQSYPPVPNWYSSYITSVIEPHFFLYATRNCIVILGLQNLRYFNSFTVSNEKVTAIAAHETFCFTAGTDKTVRVWNVLIGSLLTSYCEHKTEITALKVIRNGTVVISADKSGCIVIMNPFDKSMKRQHNVKSEVTSLAITTYNGHDYLAVGYANGLVFVEQMEQDLSTTNMFQFPNDNDAVLSLDWQKTPSDSKSWPLLALSTRRKRNIVVWNLSSQNIWTTIRLPNPPAQATEQQKSTVWIELAWSPNQINKLFLSSYIGSVVCFDLSTPSHKLCNNERLEKHSRNVFTINWFNQGKHCITTSLDKQLIRWDVKKKSCLQILKTQAGFPYSLDSPEWNHDQIAVGMGDNAIKIWQYKNTHSIMKSSTHHDYYKSDVLWRGLQGKIEKVKWHPQKEGLLAFSNEYGHVGLYDTVNSRRIPCKTYHRSPGAPFIDWGGDMRTVLEEDDMEDTLLSCGNDGVLHAYNTNNVQLPCINLTERLREKNDTWFTSLEATKSKCCSLRVDSKAKYMSLGHTNGLVEIYSLENLKLVYASSYHREAVRSLDFKCKVQFKHTTYLLEKKDYGKFIVLASGCDAGLIAIHEIELVDVNNVPDVVASHSDIKQSLKGHKKGIQDLKWSYHTDKQILASASDDSFVAVWDIEKDQPVSLFDRHRNRVLSICWCRLEHDRLFTGSEDRFIYDWKYPDFPLTGSLQNMKNLYDKERNILNQIKPTNKRKVEVSSSDPSAPPTTTGASQKKPKRESAKEKEKYSNSMAVAQESERTTSRLRKEQYCLVLTNMLFGENNMEKIIMELNNTYLNDNQRKDPTVTRYVNFWKDIDIAKQSASYHENIHELLYGDKNDIRRLIELEVTELNKRQATANLETSYSVHNNVKNDYDVSLAMDIMQAQFKLFEKDTFDANTNSCLTDWIVLAMSPMVGKQKWIELMLKQAQKLENMKQYHLAASCYIACSHIYEAIELYRRQNMFREAIALAKLRLPSEDMIIPTLFADWANALQKEEQDTLTTIWYQKGSVSNAINTLARSCKESSLFYAACLAFYFDEGTKEQRVEHWLKKLNERMSNKISDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N537</accession>
    <name>A0A1C7N537_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 5">Glucose-6-phosphate 1-epimerase</fullName>
            <ecNumber evidence="3 5">5.1.3.15</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">YMR099C</name>
        <name evidence="8" type="ORF">A0J61_07831</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Catalyzes the interconversion between the alpha and beta anomers from at least three hexose 6-phosphate sugars (Glc6P, Gal6P, and Man6P).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>alpha-D-glucose 6-phosphate = beta-D-glucose 6-phosphate</text>
            <dbReference type="Rhea" id="RHEA:16249"/>
            <dbReference type="ChEBI" id="CHEBI:58225"/>
            <dbReference type="ChEBI" id="CHEBI:58247"/>
            <dbReference type="EC" id="5.1.3.15"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the glucose-6-phosphate 1-epimerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.1.3.15" evidence="3 5"/>
    <dbReference type="EMBL" id="LUGH01000553">
        <property type="protein sequence ID" value="OBZ84118.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N537"/>
    <dbReference type="STRING" id="101091.A0A1C7N537"/>
    <dbReference type="InParanoid" id="A0A1C7N537"/>
    <dbReference type="OrthoDB" id="1659429at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047938">
        <property type="term" value="F:glucose-6-phosphate 1-epimerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd09020">
        <property type="entry name" value="D-hex-6-P-epi_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.98.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008183">
        <property type="entry name" value="Aldose_1/G6P_1-epimerase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025532">
        <property type="entry name" value="G6P_1-epimerase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011013">
        <property type="entry name" value="Gal_mutarotase_sf_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014718">
        <property type="entry name" value="GH-type_carb-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11122">
        <property type="entry name" value="APOSPORY-ASSOCIATED PROTEIN C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11122:SF13">
        <property type="entry name" value="GLUCOSE-6-PHOSPHATE 1-EPIMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01263">
        <property type="entry name" value="Aldose_epim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016020">
        <property type="entry name" value="PHexose_mutarotase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74650">
        <property type="entry name" value="Galactose mutarotase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0413">Isomerase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" evidence="6">
        <location>
            <position position="161"/>
        </location>
    </feature>
    <feature type="active site" evidence="6">
        <location>
            <position position="264"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="63"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="83"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="88"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001096"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005866"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012083"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRNR" id="PIRNR016020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR016020-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR016020-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OBZ84118.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="287" mass="31903" checksum="C355430E9A736A58" modified="2016-11-30" version="1">MPAREENKVVLLEHPSGSKAKIALFEIELLINECNKGATVTSWVVDDVERIFLAKHDGTKAIRGGIPICFPIFGTKEKIALPQHGFARNNYWEYLGIVTDNDEVAVRFGLKDTQIPQEARNAWPHSFRLTYTVTLTAKSLKTFCHLKNEDEDTFEFNTLLHTYFSVPDVTKAQVQGLTSCEYIDKVQGGAKATETNADVTIGSEVDRVYKKVQDKITLQVGNGSAIQLEKSNLKDTVVWNPWIEKAKGMADFDDEEYHNMICVEAGSVVDWVALAGGDTWTAACGAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N6F3</accession>
    <name>A0A1C7N6F3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Host cell factor 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">HCFC2</name>
        <name evidence="4" type="ORF">A0J61_07743</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000541">
        <property type="protein sequence ID" value="OBZ84206.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N6F3"/>
    <dbReference type="STRING" id="101091.A0A1C7N6F3"/>
    <dbReference type="InParanoid" id="A0A1C7N6F3"/>
    <dbReference type="OrthoDB" id="2363417at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.80">
        <property type="entry name" value="Kelch-type beta propeller"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015915">
        <property type="entry name" value="Kelch-typ_b-propeller"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46093">
        <property type="entry name" value="ACYL-COA-BINDING DOMAIN-CONTAINING PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46093:SF18">
        <property type="entry name" value="FIBRONECTIN TYPE-III DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24681">
        <property type="entry name" value="Kelch_KLHDC2_KLHL20_DRC7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117281">
        <property type="entry name" value="Kelch motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0880">Kelch repeat</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008889507" evidence="3">
        <location>
            <begin position="19"/>
            <end position="427"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OBZ84206.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="427" mass="47075" checksum="B0169CD199D65D06" modified="2016-11-30" version="1">MLTFRLLFVSASLFLVDAIVPTARYNGGCVAIRNQMFCYGGTENRQTSTNHYTLDLSTDFTVADSIKAWNTVDPGNYQVEPNSLFSIVPLNDSYLIHGGLGYASSTKFIKNVTTLYNVTAKSWSTVQAANQSLIMPSREGTSTLDSHNQLWVWGGLSDNVTNTNVTHTTYHEEFQTLDMNTLTWSLPTNITKTSSLSPRIAHTATLSKSGDVIYFIGGLQVSNGYQLSYAPMNDILQFNITNQTWSLHHSPGNTTIPSPRRLHSATAIPDTDLIFIYGGSVTDGAGTVSDYMYTLNTTSYVYTPVHATNSNQAKAGPRFGHSAVLYDKRSLFIIFGADELGSLRNDFAVLDIKNWNWVETFKADSNYPTPSSQNPPSTISNKPANTATFASSGSSSSLNNSDQVFIKFNYMKTLYFIIGITLLFSFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N6H1</accession>
    <name>A0A1C7N6H1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_07725</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000538">
        <property type="protein sequence ID" value="OBZ84226.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N6H1"/>
    <dbReference type="STRING" id="101091.A0A1C7N6H1"/>
    <dbReference type="InParanoid" id="A0A1C7N6H1"/>
    <dbReference type="OrthoDB" id="2135488at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ84226.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="77" mass="8560" checksum="59B34E27D0DC42D4" modified="2016-11-30" version="1" fragment="single">MAYERNTVEGVRSWLTAEISSNGWSSASIAKGLTDDVMTTLVHNFQQFDNRMKQAILLGVICMRKADLIALGDDLIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N6I2</accession>
    <name>A0A1C7N6I2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_07341</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000489">
        <property type="protein sequence ID" value="OBZ84608.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N6I2"/>
    <dbReference type="STRING" id="101091.A0A1C7N6I2"/>
    <dbReference type="InParanoid" id="A0A1C7N6I2"/>
    <dbReference type="OrthoDB" id="2128042at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015079">
        <property type="term" value="F:potassium ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031606">
        <property type="entry name" value="Kch1/2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36424:SF1">
        <property type="entry name" value="LOW AFFINITY K(+) TRANSPORTER 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36424">
        <property type="entry name" value="PHEROMONE-REGULATED MEMBRANE PROTEIN 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16944">
        <property type="entry name" value="KCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="42"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="81"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="226"/>
            <end position="246"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ84608.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="445" mass="52522" checksum="E4322BF81219AAC0" modified="2016-11-30" version="1">MSTNNHLKNTQKGPKWKQELSKEHKFDNIDLRAFQTTNCITVLRYLILLCSIVISFLVYIADLWTAVTLLVYDKWSLIEQPIIPFYISKWIYVGCIALSFLLLAWEIRNTMKVMDTRDVSLAVTNPLAYQTYSVKGYKYFCLLRKIKSSTKWSDVIIFYVFYTLKGWKKVIVAQAPRQIIAGMTVYALLYSAWNDQRGHFHFATDWDVYGADWQQRVTLISMSFTCILWVLSALSILLAIFLYFFVLCQIQGNLKEYCCHKIDKRIDEILENQNRRGRSKHERNQIYIQETIPKDQEASTKLEQMENSTTPIIRNKEAYQHGGDEDSIWQYYDYNTTPSAPQRPNEMHYNQPYGHHQPNPYTTQPDMHYDWQAQSNQTNSTDPSGYAYYYDPRDNYGYPAHESQTPYQPTHVAYGYQNNQGEAYHSDYQHYADTFHHQQYTHYKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N6R4</accession>
    <name>A0A1C7N6R4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">tRNA N(3)-methylcytidine methyltransferase</fullName>
            <ecNumber evidence="10">2.1.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">A0J61_07653</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">S-adenosyl-L-methionine-dependent methyltransferase.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>cytidine(32) in tRNA(Ser) + S-adenosyl-L-methionine = N(3)-methylcytidine(32) in tRNA(Ser) + S-adenosyl-L-homocysteine + H(+)</text>
            <dbReference type="Rhea" id="RHEA:50956"/>
            <dbReference type="Rhea" id="RHEA-COMP:12849"/>
            <dbReference type="Rhea" id="RHEA-COMP:12851"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:74894"/>
            <dbReference type="ChEBI" id="CHEBI:82748"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="9">
            <dbReference type="Rhea" id="RHEA:50957"/>
        </physiologicalReaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the methyltransferase superfamily. METL family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.-" evidence="10"/>
    <dbReference type="EMBL" id="LUGH01000529">
        <property type="protein sequence ID" value="OBZ84299.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N6R4"/>
    <dbReference type="FunCoup" id="A0A1C7N6R4">
        <property type="interactions" value="660"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N6R4"/>
    <dbReference type="InParanoid" id="A0A1C7N6R4"/>
    <dbReference type="OrthoDB" id="417697at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052735">
        <property type="term" value="F:tRNA (cytidine-3-)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106217">
        <property type="term" value="P:tRNA C3-cytosine methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.150:FF:000279">
        <property type="entry name" value="Methyltransferase-like protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013217">
        <property type="entry name" value="Methyltransf_12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026113">
        <property type="entry name" value="METTL2/6/8-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22809">
        <property type="entry name" value="METHYLTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22809:SF11">
        <property type="entry name" value="TRNA N(3)-METHYLCYTIDINE METHYLTRANSFERASE METTL2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08242">
        <property type="entry name" value="Methyltransf_12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037755">
        <property type="entry name" value="Mettl2_prd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 10 13" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 10 13" id="KW-0808">Transferase</keyword>
    <keyword evidence="7" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="Methyltransferase type 12" evidence="12">
        <location>
            <begin position="141"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="44"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009725"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00050646"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRNR" id="PIRNR037755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF08242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="OBZ84299.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="331" mass="38685" checksum="BCD8D19BBF91BA54" modified="2016-11-30" version="1">MSDLTEKVPETTQNGFDDQEVGKKRASSVLDVDDNKDQESSKFGSRLLTEENDVFAHNAWDHVEWGSDQEEMAKEKVSFQLDNPVPEDEQAQYYSDPAEYWNKFYQKNENRFFKDRHWLKIEFPELFETSKEDAGKKRVFEIGCGAGNTMYPLLEQNENPDLFVYAADYSKTAVDVVLGNKAYDPSRSSAFVWDLTSPEIPEQIEPGSLDMIVLIFVLSALAPEQWNQAITNIHTMLKPGGLVLFRDYGRYDLAQLRFKKNRLLKENFYIRGDGTRVYFFTPEEISQLFSKDKDKELFKIEQSAVDRRLIVNRQRKLKMYRVWLQGKFRKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N6X2</accession>
    <name>A0A1C7N6X2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">RRM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_07045</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000456">
        <property type="protein sequence ID" value="OBZ84905.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N6X2"/>
    <dbReference type="STRING" id="101091.A0A1C7N6X2"/>
    <dbReference type="InParanoid" id="A0A1C7N6X2"/>
    <dbReference type="OrthoDB" id="336240at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="231"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="259"/>
            <end position="273"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ84905.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="567" mass="64438" checksum="84EA3FEE52BCEA78" modified="2016-11-30" version="1">MRIQIVHPKCKINDTKTVRRSEDNVTPWKQPTLLPEENKKVDMMKFKQRVIDEWLLSSEPMVSANEEQPMQHSLPFSPFTQQVMHDQQDKRDCPTAEFDNFHISNAPHPNNHVPRSLPSTSALTGTGRLIPLNPFQMNYGVDWSGYVNHSHMNANVWRPSYLNDARQPFDLFSSQAASETTVGQQTNPTSVGTSMLTTLPLSNKTLSHGSASSIPRLQLATSSTAMFKGLESNMPSTKAEKTTWSKVVKGESQTEPPFTGTSSSSPGSSNNTSTRYITDSISYMTSKLQTDGNIQKKYTVIKVTNFPWEVNASVIRQVFEQSANFILPPELPQCVHVMMDAKSGKTLGVAFVEVVLKLKNRQDIIHALKSLSMSCIQCTRRPQFSLSSYDELYSQLFPNWKGQFLDGLAISQPPLKTVHNMIVDSKKSAFFISQKELQALLNICRNYKINYNRRCSERPFEYLISIVMHMPWNQVKTVTTTQRDILYECYKLATASLYEHTSKKMHSFESDILLRFVRAGLLCDGFTYRQKNDILHHAHMECPEDLRSYIEAPAILNDSEFTNLLRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N716</accession>
    <name>A0A1C7N716_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Protein VTS1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">VTS1_2</name>
        <name evidence="6" type="ORF">A0J61_07073</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000459">
        <property type="protein sequence ID" value="OBZ84882.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N716"/>
    <dbReference type="InParanoid" id="A0A1C7N716"/>
    <dbReference type="OrthoDB" id="2155283at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000932">
        <property type="term" value="C:P-body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000289">
        <property type="term" value="P:nuclear-transcribed mRNA poly(A) tail shortening"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.50">
        <property type="entry name" value="Transcription Factor, Ets-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001660">
        <property type="entry name" value="SAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013761">
        <property type="entry name" value="SAM/pointed_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050897">
        <property type="entry name" value="SMAUG/VTS1_RNA-bind"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057327">
        <property type="entry name" value="Vts1_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12515:SF5">
        <property type="entry name" value="PROTEIN SMAUG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12515">
        <property type="entry name" value="STERILE ALPHA MOTIF DOMAIN CONTAINING PROTEIN 4-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07647">
        <property type="entry name" value="SAM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25479">
        <property type="entry name" value="Vts1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00454">
        <property type="entry name" value="SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47769">
        <property type="entry name" value="SAM/Pointed domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50105">
        <property type="entry name" value="SAM_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="SAM" evidence="5">
        <location>
            <begin position="520"/>
            <end position="578"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="37"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="194"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="270"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="362"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="426"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="41"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="65"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="270"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="314"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="342"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="367"/>
            <end position="377"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50105"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OBZ84882.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="617" mass="68746" checksum="2A3D7B4A019A7D72" modified="2016-11-30" version="1">MATTHEIHRVMDERLLFGAFQRQSHHIKSFPSELVHLPGQQRRSPIRSSNSTIGNRVQPSHYKSKASSEILQTEPSRENYRDSPEAEAIDRWFENIQRYEQMLEEVAAASLDQDFKDELQHINTWLQCRSDAERTAALYTIVQNASQIQIHFLITVLQKLANSHSDPYPAGQDTTSNSEIISYYRSLHVNNSQSVISSESDRRRHLYPPPVSTNNRKFGRFSSAVSEPNDVGRQNRELFASGSLAGGLSHPGPLYEKALAARAQLQAMSSQDTSAQSSTATSSILSSSSSSSSSSLGQHGSTGGLFLSPPKLRSPSNTSHLSSQPLFSPRSAKDWPFPIGTDMNTSPDSDRQSWSFGSLTNKKKHTVSSAPGSTASSVIGAKRNEDRLPWTIQEEQEDYSKLSATITSSLNALEQAQARLKQELPHSKPSLTNKPSVVWSPKASPIQTPKTDIIPGLSPSPSTPLPKQVAFAFTETNNEQALHEEEKQLTGLARRRKRSSAARALKDKIAAETVDFELMKDVQNWLRSLRLHKYGHAFIGLDWKQVVRMSDQDMIDAGVNTIGARRKLLKVFENVVNHCEENMSTSSQVNECGYYEFVPDHFASRVLSDYVRTQILL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N7L9</accession>
    <name>A0A1C7N7L9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Copper-fist domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">A0J61_06844</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000433">
        <property type="protein sequence ID" value="OBZ85102.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N7L9"/>
    <dbReference type="STRING" id="101091.A0A1C7N7L9"/>
    <dbReference type="InParanoid" id="A0A1C7N7L9"/>
    <dbReference type="OrthoDB" id="5600085at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005507">
        <property type="term" value="F:copper ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006878">
        <property type="term" value="P:intracellular copper ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006879">
        <property type="term" value="P:intracellular iron ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.430.10:FF:000001">
        <property type="entry name" value="Copper fist DNA-binding protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.430.10">
        <property type="entry name" value="Copper fist DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051763">
        <property type="entry name" value="Copper_Homeo_Regul"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001083">
        <property type="entry name" value="Cu_fist_DNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036395">
        <property type="entry name" value="Cu_fist_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28088">
        <property type="entry name" value="TRANSCRIPTIONAL ACTIVATOR HAA1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28088:SF5">
        <property type="entry name" value="TRANSCRIPTIONAL ACTIVATOR HAA1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00649">
        <property type="entry name" value="Copper-fist"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00617">
        <property type="entry name" value="COPPERFIST"/>
    </dbReference>
    <dbReference type="SMART" id="SM01090">
        <property type="entry name" value="Copper-fist"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00412">
        <property type="entry name" value="Cu_FIST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57879">
        <property type="entry name" value="Zinc domain conserved in yeast copper-regulated transcription factors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50073">
        <property type="entry name" value="COPPER_FIST_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0186">Copper</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0804">Transcription</keyword>
    <keyword evidence="5" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Copper-fist" evidence="9">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="92"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="139"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="139"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="161"/>
            <end position="181"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OBZ85102.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="307" mass="33407" checksum="D461B995A83EFBB8" modified="2016-11-30" version="1">MLMNGEKWACETCIKGHRATHCKHTDRKLVLVKKKGRPSTQCKRCKELRVMHGKIQTPTKRHVTTNLNTPPVIRKKQSETLRPIAPKQKETVTSCCGNKYPSPKPNHQSVSPPPLPTVLQPSVSLSIPISLKPSTQPTLLASMSSSTPVQSTLIPPIHPVTTSNSNPKSSCCSKKTSSDPPQNSQSESVPLPHIPPPTSCCGPPSKNQQGEIIRVVTCRCGDSCACIGCDAHPSRAMKDEKSDVYIGFDSKKRLSISSIVLSKNDQIQQEPSSVLIENGVSFCGCGCSKTFEECSGCFQGFLCQDYH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N7R3</accession>
    <name>A0A1C7N7R3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">PNPLA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">A0J61_06761</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000424">
        <property type="protein sequence ID" value="OBZ85185.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N7R3"/>
    <dbReference type="FunCoup" id="A0A1C7N7R3">
        <property type="interactions" value="21"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N7R3"/>
    <dbReference type="InParanoid" id="A0A1C7N7R3"/>
    <dbReference type="OrthoDB" id="10049244at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004806">
        <property type="term" value="F:triacylglycerol lipase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016042">
        <property type="term" value="P:lipid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006641">
        <property type="term" value="P:triglyceride metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd07229">
        <property type="entry name" value="Pat_TGL3_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1090.10">
        <property type="entry name" value="Cytosolic phospholipase A2 catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016035">
        <property type="entry name" value="Acyl_Trfase/lysoPLipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050301">
        <property type="entry name" value="NTE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002641">
        <property type="entry name" value="PNPLA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021771">
        <property type="entry name" value="Triacylglycerol_lipase_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14226">
        <property type="entry name" value="NEUROPATHY TARGET ESTERASE/SWISS CHEESE D.MELANOGASTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14226:SF44">
        <property type="entry name" value="TRIACYLGLYCEROL LIPASE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11815">
        <property type="entry name" value="DUF3336"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01734">
        <property type="entry name" value="Patatin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52151">
        <property type="entry name" value="FabD/lysophospholipase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51635">
        <property type="entry name" value="PNPLA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0442">Lipid degradation</keyword>
    <keyword evidence="3" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PNPLA" evidence="5">
        <location>
            <begin position="155"/>
            <end position="331"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022963"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51635"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OBZ85185.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="512" mass="58610" checksum="83CF922D2EAE9947" modified="2016-11-30" version="1">MDGMLIKLNEYKESKPENRLLRYLKSAKTFQEWQDKARELDEYLKNDKWVQKPESRIYDYKLIASRLDHLRKARLDNDVNSMTYLLRGGLLRNFGGICDRKLFSHSYLGTKQLVQDYMNEVVAQIELIESTPDFDAQAKLKFFSDTRQSFGCSALVLQGSTALALYHIGVVKALNEQGLLPRIISGTAIGAMIAALICIHTDDELPYILQPDGINLTAFSRKGKTGHFKRRITRFMKYGYLMDMKVLQECVRSNVGDLTFEEAYARSKRVLNISVSSSRTQEVPQILNYLTAPNVLIWSAACCSTASVGLFGSCDLMAKDKNGNIVKWISTAVKWNHWSEKPASESEEPLYRLSELFNVNHFIVSQASLYAIPFISKAQNLQHETLLHKLAFIVASEFKHRLHQLDQLHILPHQLRGVIEEKMSGNVNIVPELAFSDFNILFSNPSHQSLAYWILHGERSVWPLMAFIRTRCMIELALDKAVLRLKAMNVEREPVVVRSRHVQNKKRAKSMH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N836</accession>
    <name>A0A1C7N836_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">tRNA (adenine(58)-N(1))-methyltransferase non-catalytic subunit TRM6</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">tRNA(m1A58)-methyltransferase subunit TRM6</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">TRM6</name>
        <name evidence="8" type="ORF">A0J61_07144</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TRM6/GCD10 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000466">
        <property type="protein sequence ID" value="OBZ84806.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N836"/>
    <dbReference type="FunCoup" id="A0A1C7N836">
        <property type="interactions" value="588"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N836"/>
    <dbReference type="InParanoid" id="A0A1C7N836"/>
    <dbReference type="OrthoDB" id="10254665at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031515">
        <property type="term" value="C:tRNA (m1A) methyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0160107">
        <property type="term" value="F:tRNA (adenine(58)-N1)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030488">
        <property type="term" value="P:tRNA methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.330.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017423">
        <property type="entry name" value="TRM6"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12945">
        <property type="entry name" value="TRANSLATION INITIATION FACTOR EIF3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12945:SF0">
        <property type="entry name" value="TRNA (ADENINE(58)-N(1))-METHYLTRANSFERASE NON-CATALYTIC SUBUNIT TRM6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04189">
        <property type="entry name" value="Gcd10p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF038170">
        <property type="entry name" value="tRNA_m1A_mtfrase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0808">Transferase</keyword>
    <keyword evidence="4" id="KW-0819">tRNA processing</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="402"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="403"/>
            <end position="422"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008320"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00021704"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00032319"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OBZ84806.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="422" mass="48198" checksum="A07ED2E0DDE3A4B8" modified="2016-11-30" version="1">MTDQNECIQQNQFVIIEMPSGNAKMVNLKPNTNISLGKFGTFKSDQLIGKPWGLSYEIVGKKGEIRPVEHVSKHETVEETAANNQMIVDDGSVQKLSQEEVLKLKERGLKGELATEDIIKMMVDSHTEFEKKTEYSKAKYIARKKKKFMKVFTPIRPTLCSITNYFYNKNPEKIKHLRIDTLSQLLSLGNVHANSKLLVVDDTQGLIVSSLLERMGGFGQLVALHEGEFHNYDILRYMNFPKSTQSILHTVPFGLVDPSVPEETFELLSAEEIERLDEDQTRAYNRRKTSWEYKVKSRKLLYEGNFDGLILSSSYQPETVLKELKQYISGSRPVVIYSFSKEVLLTAAYWMRRSKDFLNADITESSLREYQVLPGRMHPHMMTSAGGGYILSGLRVIDCPYDPSKRSEGDDRRSKKSKVETV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N843</accession>
    <name>A0A1C7N843_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Xylanolytic transcriptional activator regulatory domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">A0J61_06722</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000420">
        <property type="protein sequence ID" value="OBZ85227.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N843"/>
    <dbReference type="InParanoid" id="A0A1C7N843"/>
    <dbReference type="OrthoDB" id="2406834at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050815">
        <property type="entry name" value="TF_fung"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007219">
        <property type="entry name" value="XnlR_reg_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47338:SF5">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47338">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04082">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00906">
        <property type="entry name" value="Fungal_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Xylanolytic transcriptional activator regulatory" evidence="7">
        <location>
            <begin position="229"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="526"/>
            <end position="565"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="579"/>
            <end position="639"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="652"/>
            <end position="673"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="710"/>
            <end position="745"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="526"/>
            <end position="555"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="586"/>
            <end position="598"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="599"/>
            <end position="624"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="629"/>
            <end position="639"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="662"/>
            <end position="673"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="711"/>
            <end position="720"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="6">
        <location>
            <begin position="721"/>
            <end position="740"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OBZ85227.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="797" mass="90481" checksum="F7E292869C15E507" modified="2016-11-30" version="1" fragment="single">GSLESDQQETPNETVYDNMDGFFDSSSNRATKDNDDHILFADTSSVNHNKLKRRGPLMESRISNTLGALGENLRKMSSADSSRLAEKLLNTTDSYGSFIMWMPEPSLPSRYSGSIEMPSREIQMALIDQFFSERYECIAYIPRHHFYEQIKTKGLLITPLLLNTIYAHAARFVDIPDCPKTEVFYQRARRLIDDFLDVPRVSTVAALCLLSLYESSPSIYRPGSLQCRQWQYSGMACRMALELGLHDDTNIHNGLSSVDIELRRRVFWGCYDLDKFQSGGWERPWMISGCYIKTMLPSILPEETEDDRAIVSILVKRIQFMRLVENDLTLLSAHRSFQTGSNEPFLGVKKEEIMFDISEHHIKLHHWLRTLPPDMQWTPISSVSVKEVLDLPVPRPCLAHIHLYYNIATLSVLSNVPTTSLVQFQTRVTATCITQLVYCMCQTPSYIVKFDFLVHGLISAVKIHLQYLNDIDINLAQQAWLLFDRSIWCMQLISNYAVIPNCTKFLQQVQHVYGLHIPTLNSQNNNSSDDCSIHSNGNENSSYISNENNSNNDSSTIPPQKRFHNDTPKQIDLVEKRGAMPQNQISSQTSSSSSTQFSENMNAMPSYLNWSSNLDSRQTNTSNDMLRLSNDNSDASDSRNVLYLDQQYRLHGRSKSHYDNPPRTNSPPIWTNSHQELNYTMNNRSSSHPTSTNNYNSGDIIVPSQLLVDDSSYPRQSSTSSPPPLPPLSATPLLPLPNSPSTPISTRFTSNSALLWQDPVPNPNIPVLTENQIPARKGLGAIYLSSRQHYEKMIKKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N959</accession>
    <name>A0A1C7N959_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">PX domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_06501</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000394">
        <property type="protein sequence ID" value="OBZ85458.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N959"/>
    <dbReference type="STRING" id="101091.A0A1C7N959"/>
    <dbReference type="InParanoid" id="A0A1C7N959"/>
    <dbReference type="OrthoDB" id="2117459at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035091">
        <property type="term" value="F:phosphatidylinositol binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047168">
        <property type="entry name" value="LEC1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024554">
        <property type="entry name" value="LEC1-like_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47185">
        <property type="entry name" value="PX DOMAIN-CONTAINING PROTEIN YPR097W"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47185:SF1">
        <property type="entry name" value="PX DOMAIN-CONTAINING PROTEIN YPR097W"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12825">
        <property type="entry name" value="DUF3818"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PX" evidence="1">
        <location>
            <begin position="66"/>
            <end position="184"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ85458.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="324" mass="36777" checksum="7144361933B5A6C1" modified="2016-11-30" version="1">MNEQSKELAKDIEELERKINDPLLCQKIANAVQTEIPEGLKLDNSSPINETLELLKDSNIEPVLTPQQILKEQESLMSLVFQGVTGEVTKDLFAIFYEPLAQVYKSANISETIGHVSAFVNDLIQVVDNVDAQDASHTAQPFIELVKRHEDKFYDFVHNVHAQDKTKLFDSLLGYVNSIFSFVSTGIPTKIDLDAIVTEAGISESEYPALKQEIQSVCEYHLKRKQRHLERKRQKMMTTSDIADNQEIFDFLPENKQVMNVFNDMAEIGSDSEDDMSIYAESIKSNNGSSSNLKAHEMTLRSPKLHIVPRIGSVFVEHVRRIMY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N982</accession>
    <name>A0A1C7N982_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Iron-sensing transcription factor 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">fep1_0</name>
        <name evidence="9" type="ORF">A0J61_06768</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000424">
        <property type="protein sequence ID" value="OBZ85189.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N982"/>
    <dbReference type="STRING" id="101091.A0A1C7N982"/>
    <dbReference type="InParanoid" id="A0A1C7N982"/>
    <dbReference type="OrthoDB" id="515401at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000122">
        <property type="term" value="P:negative regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00202">
        <property type="entry name" value="ZnF_GATA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.50.10">
        <property type="entry name" value="Erythroid Transcription Factor GATA-1, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039355">
        <property type="entry name" value="Transcription_factor_GATA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000679">
        <property type="entry name" value="Znf_GATA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013088">
        <property type="entry name" value="Znf_NHR/GATA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10071:SF281">
        <property type="entry name" value="BOX A-BINDING FACTOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10071">
        <property type="entry name" value="TRANSCRIPTION FACTOR GATA FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00320">
        <property type="entry name" value="GATA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00619">
        <property type="entry name" value="GATAZNFINGER"/>
    </dbReference>
    <dbReference type="SMART" id="SM00401">
        <property type="entry name" value="ZnF_GATA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57716">
        <property type="entry name" value="Glucocorticoid receptor-like (DNA-binding domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00344">
        <property type="entry name" value="GATA_ZN_FINGER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50114">
        <property type="entry name" value="GATA_ZN_FINGER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 6" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="GATA-type" evidence="8">
        <location>
            <begin position="55"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="103"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="105"/>
            <end position="121"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00094"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50114"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OBZ85189.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="215" mass="24597" checksum="5342BF338CBD54E6" modified="2016-11-30" version="1">MHLQQIKTRKRSLTRCAECQLSFRPHVWGRESGKGPVCDQCSNKTFRFIEENNKETENVICANCQATTTPLWRRDAKGNTICNACGLYYKLHHVHRPATMMRTEIKRRRRCASNEKKKNRKLSIDSDSSSLSSEDKLTLPPIQSYYPTPCSHTSSSIESLYSRRLELQQEVSRLSKLLSSTVAKLSDVDQAIIAHQPEKEEESKLPPISLGFPIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N9M2</accession>
    <name>A0A1C7N9M2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Vesicular GABA transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">unc-47_1</name>
        <name evidence="10" type="ORF">A0J61_07903</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the amino acid/polyamine transporter 2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000564">
        <property type="protein sequence ID" value="OBZ84044.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N9M2"/>
    <dbReference type="STRING" id="101091.A0A1C7N9M2"/>
    <dbReference type="InParanoid" id="A0A1C7N9M2"/>
    <dbReference type="OrthoDB" id="40134at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005774">
        <property type="term" value="C:vacuolar membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015179">
        <property type="term" value="F:L-amino acid transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1740.10">
        <property type="entry name" value="Amino acid/polyamine transporter I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013057">
        <property type="entry name" value="AA_transpt_TM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22950">
        <property type="entry name" value="AMINO ACID TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22950:SF692">
        <property type="entry name" value="TRANSMEMBRANE AMINO ACID TRANSPORTER FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01490">
        <property type="entry name" value="Aa_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0029">Amino-acid transport</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="45"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="70"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="112"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="158"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="182"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="217"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="256"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="298"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="340"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="370"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="401"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="domain" description="Amino acid transporter transmembrane" evidence="9">
        <location>
            <begin position="39"/>
            <end position="421"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008066"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OBZ84044.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="432" mass="46848" checksum="D9A14A13E50A1F04" modified="2016-11-30" version="1">MTSFNEKKADYQHSINDVASEREYEYANEGMVDINREHAGSSKMAYFNVVCVVAGTGTLGLPVALKQGGWLGVLILALSWFMSVYTGIILIRCLYANGKTRLTTYKEIATTAFGAIGGWITFFFNAWILLGAPILYMVLSGTNLNQLCKGTVAEIGDTPWIIISCVIVAIPFILVKTLKEVAWMSAFGALATVVVVLICLVMSAMDKPNQVDVVHHSVIWEMFPIALSTISFSFGGNVVYPHVEASMKTPRDWPKVVAAGLSTCAALYFITAISGYLIYGDNVVSPIYNSIPAGVAQIVAVVIITLHVLMAAPILTTSFSLDIEEMLNISVERFGKVKEFFIRAAIRVATMAVVAVVACTVPHFGALMSLIGAFANCILIFVLPIACYLKLTGIRNKPFYELAWCALTVLLGIVGLIFGTMEAIKELISAYA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N9W7</accession>
    <name>A0A1C7N9W7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Proteasome subunit alpha type</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">PAC1_1</name>
        <name evidence="8" type="ORF">A0J61_06027</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="6">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5 6">Belongs to the peptidase T1A family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000345">
        <property type="protein sequence ID" value="OBZ85915.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N9W7"/>
    <dbReference type="FunCoup" id="A0A1C7N9W7">
        <property type="interactions" value="574"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N9W7"/>
    <dbReference type="InParanoid" id="A0A1C7N9W7"/>
    <dbReference type="OrthoDB" id="431557at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019773">
        <property type="term" value="C:proteasome core complex, alpha-subunit complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034515">
        <property type="term" value="C:proteasome storage granule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010499">
        <property type="term" value="P:proteasomal ubiquitin-independent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0080129">
        <property type="term" value="P:proteasome core complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043161">
        <property type="term" value="P:proteasome-mediated ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd03752">
        <property type="entry name" value="proteasome_alpha_type_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.20.10:FF:000031">
        <property type="entry name" value="Proteasome subunit alpha type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.10">
        <property type="entry name" value="Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050115">
        <property type="entry name" value="Proteasome_alpha"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023332">
        <property type="entry name" value="Proteasome_alpha-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000426">
        <property type="entry name" value="Proteasome_asu_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016050">
        <property type="entry name" value="Proteasome_bsu_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001353">
        <property type="entry name" value="Proteasome_sua/b"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003075">
        <property type="entry name" value="PRK03996.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11599">
        <property type="entry name" value="PROTEASOME SUBUNIT ALPHA/BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00227">
        <property type="entry name" value="Proteasome"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10584">
        <property type="entry name" value="Proteasome_A_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00948">
        <property type="entry name" value="Proteasome_A_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="N-terminal nucleophile aminohydrolases (Ntn hydrolases)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00388">
        <property type="entry name" value="PROTEASOME_ALPHA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51475">
        <property type="entry name" value="PROTEASOME_ALPHA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00854">
        <property type="entry name" value="PROTEASOME_BETA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="3 5 6" id="KW-0647">Proteasome</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Proteasome alpha-type subunits" evidence="7">
        <location>
            <begin position="5"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002000"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00808"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS00388"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OBZ85915.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="249" mass="27536" checksum="B27E992CB0B5E6F3" modified="2016-11-30" version="1">MARRYDSRTTIFSPEGRLYQVEYAMEAISLAGIALGILAKDGVVIAAEKKVTAKLLETSATSEKIYKLNDNIICGVAGITADANILINWTRASAQRYLFAYNEEIPVEQLVQNLCDLKQGYTQYGGLRPFGVSFIFAGYDEHHGFQLYHSDPSGNYGGWKATCIGANNATAQSILKQDHKDDMTLEEAKALAIKVLSKTMDSTTLTSEKLEFATIRLEDEKVKYDLYKPEEIDALLKEQNVGAPSDETA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NAB6</accession>
    <name>A0A1C7NAB6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Ras GTPase-activating-like protein IQGAP1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">IQGAP1_0</name>
        <name evidence="4" type="ORF">A0J61_05959</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000339">
        <property type="protein sequence ID" value="OBZ85991.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NAB6"/>
    <dbReference type="FunCoup" id="A0A1C7NAB6">
        <property type="interactions" value="179"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NAB6"/>
    <dbReference type="InParanoid" id="A0A1C7NAB6"/>
    <dbReference type="OrthoDB" id="775356at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0110085">
        <property type="term" value="C:mitotic actomyosin contractile ring"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051015">
        <property type="term" value="F:actin filament binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005516">
        <property type="term" value="F:calmodulin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1903479">
        <property type="term" value="P:mitotic actomyosin contractile ring assembly actin filament organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd21206">
        <property type="entry name" value="CH_IQGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.418.10">
        <property type="entry name" value="Calponin-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.506.10">
        <property type="entry name" value="GTPase Activation - p120gap, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001715">
        <property type="entry name" value="CH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036872">
        <property type="entry name" value="CH_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000593">
        <property type="entry name" value="RasGAP_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023152">
        <property type="entry name" value="RasGAP_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001936">
        <property type="entry name" value="RasGAP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008936">
        <property type="entry name" value="Rho_GTPase_activation_prot"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14149:SF14">
        <property type="entry name" value="CALPONIN-HOMOLOGY (CH) DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14149">
        <property type="entry name" value="RAS GTPASE-ACTIVATING PROTEIN WITH IQ MOTIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00307">
        <property type="entry name" value="CH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00616">
        <property type="entry name" value="RasGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03836">
        <property type="entry name" value="RasGAP_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00033">
        <property type="entry name" value="CH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00323">
        <property type="entry name" value="RasGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47576">
        <property type="entry name" value="Calponin-homology domain, CH-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48350">
        <property type="entry name" value="GTPase activation domain, GAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143885">
        <property type="entry name" value="RGC domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50021">
        <property type="entry name" value="CH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50096">
        <property type="entry name" value="IQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00509">
        <property type="entry name" value="RAS_GTPASE_ACTIV_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50018">
        <property type="entry name" value="RAS_GTPASE_ACTIV_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Calponin-homology (CH)" evidence="3">
        <location>
            <begin position="78"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="domain" description="Ras-GAP" evidence="2">
        <location>
            <begin position="580"/>
            <end position="808"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="270"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="270"/>
            <end position="298"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50018"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50021"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OBZ85991.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="1236" mass="143576" checksum="FFC6AF03B0822C00" modified="2016-11-30" version="1">MSIHATPLKKLSVMAGKDGLTNLHIPTITEDAEDVIDQTNKSNKFVYAGRIRLQKDEKTSTSQWMDKQRTNLLAYEYLCHIGEAKEWIEDCLQDEIDPIIKLEEAMRNGIVLARLAEWMVPGIVRKIFQDKRLQFRHSDNINYFFDALKVARLPQIFWFELTDLYEKKNVPKVIYCIHALSHLLSRRNLAPNIKNLVGQLHFTNEELSATQRHLDLSGIVMPNFTNVGSSLRKELNEEEDENENVLNISYCSDRTTDISTPDLIIEEEYEDDEDDEDENESIFELEQYDTNSEEELSEEEKTERYWSDKANLDKLVLCQAFIRTWIAQRNYKLRSQLYKSKYVTSFITQIQAQVRGQATRHYNETQKMDYRAQARFICKIQAAVRARSVRIQQRQRIDHYKDKLASVVQVQSLIRHKLMGAAYRKLKTYDSPTVGIVKSFIHLLDDSDLDFDRELTQEELRQQIIESIKENNQLDAHVNTLDIQIALFLKNTITIEDLIRHNGAFKKKNEQKLLISETIKSSKTNPFSLNGIDKESRRRLELFQELVYLLQTEPKYLARLLSMTSRQDLGHYASHKLIESTVLSLFGYATNSREEYLLINLCKYCIAEEMKTVESTQEFMRGNYTFMKLVVQTNRGAKEREFFRALLCPLVNEIVNNDFLDLETDPVSIYHKAINDEECRTGMPSNRPHAITSQDALADPEVRDTFVIHLRNLREITEQFFVAITSIVNSVPYGIRVVARELRLILEENFPDEPQERIIRIIGNFIYYRYLNPAIVAPEQYDVIDAVINPMQRKNLAEVSKMLQHISSGTVFEDTHDIFLAPLNEYVADATIRFGEWFFALTDVEDPESYFGMHSLADQTNTHKPIVYLSPNELFHLHYTIQANLESLEPEGDGILHTIVNEIGPSAYHPNAELPESMVCLRLSNNSENIPLDPTARLQQLLVDTKRLVIYVIKIQSGQDLAEIFASPVTSEHEEAWSRLKRREFLDGSEEHAILSKRRNLQLGQTESPLDLHSVNFFQLKSIAHRLVEHLERCKVIANNNNYQDVINMIARDITGKNSRRIQRDRELARMRLTLSHLKEKRDYLLEQGNSYEGYLDSCMMAMATKRGKKQKFTLPFTRQYFHMRGLQKSGLVPTFGSYKYTAKQLYERNILLELTDIPKRHYDRIPIILSMDQAGIITIEGSYAGWSMSSVQVDMRYEELLQTQFEGVQTVTVLDGMAKVNVNLLIYLINKKFYT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NAI3</accession>
    <name>A0A1C7NAI3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_05933</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000336">
        <property type="protein sequence ID" value="OBZ86020.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="InParanoid" id="A0A1C7NAI3"/>
    <dbReference type="OrthoDB" id="2275573at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="71"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="73"/>
            <end position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ86020.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="173" mass="19580" checksum="CD5C2FD91D9786C1" modified="2016-11-30" version="1">MELLEPQDSAKIEIGGTETDTSPLVPTPPIHHQIEIPDRRQSQLYTIYHNLGQEMQINVNKRRSFYACQSTESDNTPSISCSSSSSLTRSATWXPSNNNNTNSSNHSSNENDAHLQPADMIPTRRTSRNYSEDPEIQAKLNAVLTSERTFHLSHILRENNPTRQIKTNTHMLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NAM5</accession>
    <name>A0A1C7NAM5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">Ech1</name>
        <name evidence="9" type="ORF">A0J61_05931</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="2">Lipid metabolism; fatty acid beta-oxidation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Peroxisome</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the enoyl-CoA hydratase/isomerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000336">
        <property type="protein sequence ID" value="OBZ86018.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NAM5"/>
    <dbReference type="STRING" id="101091.A0A1C7NAM5"/>
    <dbReference type="InParanoid" id="A0A1C7NAM5"/>
    <dbReference type="OrthoDB" id="14970at2759"/>
    <dbReference type="UniPathway" id="UPA00659"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005777">
        <property type="term" value="C:peroxisome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051750">
        <property type="term" value="F:delta(3,5)-delta(2,4)-dienoyl-CoA isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006635">
        <property type="term" value="P:fatty acid beta-oxidation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd06558">
        <property type="entry name" value="crotonase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.12.10:FF:000004">
        <property type="entry name" value="Delta3,5-delta2,4-dienoyl-CoA isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.226.10:FF:000024">
        <property type="entry name" value="Delta3,5-delta2,4-dienoyl-CoA isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.226.10">
        <property type="entry name" value="2-enoyl-CoA Hydratase, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.12.10">
        <property type="entry name" value="Lyase 2-enoyl-coa Hydratase, Chain A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045002">
        <property type="entry name" value="Ech1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001753">
        <property type="entry name" value="Enoyl-CoA_hydra/iso"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014748">
        <property type="entry name" value="Enoyl-CoA_hydra_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43149:SF1">
        <property type="entry name" value="DELTA(3,5)-DELTA(2,4)-DIENOYL-COA ISOMERASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43149">
        <property type="entry name" value="ENOYL-COA HYDRATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00378">
        <property type="entry name" value="ECH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="ClpP/crotonase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0007">Acetylation</keyword>
    <keyword evidence="4" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="8 9" id="KW-0413">Isomerase</keyword>
    <keyword evidence="6" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="7" id="KW-0576">Peroxisome</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004275"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005005"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022990"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OBZ86018.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="259" mass="28367" checksum="E570B0857D298059" modified="2016-11-30" version="1">MSAYQYETVKVDITAEGIAHVQLNRPKKLNAFNDQLILDVHNVFRQIHADHEILVVVVSGSGRMFTAGIDLMETNIGKLMTDGDPARNTYRNRVTIENFQDAFTAIENCSKPVIAAIHNGCYGAGVDLVTACDIRYCTKDSLFCVKEVDVGLAADVGTLQRLPKVIGNSSLVKELCYTGRNMYADEALQCGFVNRVAENHEDVLAQAFKTAKNIASKSPVAVVGTKHLLNYSRDHSVAEGLAYTVTWNAPMLNTEVGNI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NAV2</accession>
    <name>A0A1C7NAV2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Putative membrane protein C3B8.06</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">SPBC3B8.06</name>
        <name evidence="6" type="ORF">A0J61_05708</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000316">
        <property type="protein sequence ID" value="OBZ86245.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NAV2"/>
    <dbReference type="FunCoup" id="A0A1C7NAV2">
        <property type="interactions" value="17"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NAV2"/>
    <dbReference type="InParanoid" id="A0A1C7NAV2"/>
    <dbReference type="OrthoDB" id="4005299at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd08760">
        <property type="entry name" value="Cyt_b561_FRRS1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1770">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018825">
        <property type="entry name" value="DUF2427"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018827">
        <property type="entry name" value="YTP1_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31685:SF3">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_6G12730)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31685">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_6G12730)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10348">
        <property type="entry name" value="DUF2427"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10355">
        <property type="entry name" value="Ytp1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008889577" evidence="3">
        <location>
            <begin position="21"/>
            <end position="564"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="54"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="90"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="121"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="282"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="312"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="352"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="390"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="429"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="459"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="498"/>
            <end position="519"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="531"/>
            <end position="553"/>
        </location>
    </feature>
    <feature type="domain" description="DUF2427" evidence="4">
        <location>
            <begin position="51"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="domain" description="Protein YTP1-like C-terminal" evidence="5">
        <location>
            <begin position="286"/>
            <end position="554"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="154"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="180"/>
            <end position="197"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF10348"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF10355"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OBZ86245.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="564" mass="64409" checksum="3AA4EAF5941AE1EF" modified="2016-11-30" version="1">MYKWFSLLVFNLFYVQFTKAQHHHAGMMGDEPVPAFNATGDEPMSYALFPAEKGYFYIHVAMMVIAFWILMPIGVMLGIAKSSLHVPVQLLSFCFAMVGFFFAKLYGHSTPHLYAGNSHHTLGWILFLFMIVQMVVGIVRKVANAVEKHNNYERVQNDEEDHLIHSPGPSTLTASSSHSQHSDRHSEASGETLHMGEFDLDKHERSRHAMEEDEDDDDRRQFIMSDHDIQLNSHSENVTMRMFQMASPYIPNVVKNAFIALAYNRFTTVVCRYYHQVMGRTFVVLIFVQTLSGLVVYHGVCRSWEVLGCIAHLIKGGIFFFYGIGTFGRYLGAFANRGWAWNRVQNGSSFSFEMIECSLIFVYGITNTWMEHFGQDSRWTHKDLEHASLAFMWWWCGLIGILVESRAVRRLLERTVLTTNRTEVQKDGYSLNPFPALTVLMTGISMGNHHQDTQYSSNIHYMWGLLLACAALCRFVTYITLYRNQPQDAQPSRPPSELLGAFLLICGSILFMASNSGTLLWLRRNNVDSMFLMNVCVALTSMTLCYVAALQIIKSWAEKREASK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NAY4</accession>
    <name>A0A1C7NAY4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Aldehyde dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">aldA_0</name>
        <name evidence="6" type="ORF">A0J61_06154</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the aldehyde dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000358">
        <property type="protein sequence ID" value="OBZ85796.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NAY4"/>
    <dbReference type="STRING" id="101091.A0A1C7NAY4"/>
    <dbReference type="InParanoid" id="A0A1C7NAY4"/>
    <dbReference type="OrthoDB" id="310895at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004030">
        <property type="term" value="F:aldehyde dehydrogenase [NAD(P)+] activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019413">
        <property type="term" value="P:acetate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd07091">
        <property type="entry name" value="ALDH_F1-2_Ald2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.605.10:FF:000001">
        <property type="entry name" value="Aldehyde dehydrogenase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.605.10:FF:000026">
        <property type="entry name" value="Aldehyde dehydrogenase, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.309.10:FF:000001">
        <property type="entry name" value="Mitochondrial aldehyde dehydrogenase 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.605.10">
        <property type="entry name" value="Aldehyde Dehydrogenase, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.309.10">
        <property type="entry name" value="Aldehyde Dehydrogenase, Chain A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016161">
        <property type="entry name" value="Ald_DH/histidinol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016163">
        <property type="entry name" value="Ald_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016160">
        <property type="entry name" value="Ald_DH_CS_CYS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029510">
        <property type="entry name" value="Ald_DH_CS_GLU"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016162">
        <property type="entry name" value="Ald_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015590">
        <property type="entry name" value="Aldehyde_DH_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11699">
        <property type="entry name" value="ALDEHYDE DEHYDROGENASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00171">
        <property type="entry name" value="Aldedh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53720">
        <property type="entry name" value="ALDH-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00070">
        <property type="entry name" value="ALDEHYDE_DEHYDR_CYS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00687">
        <property type="entry name" value="ALDEHYDE_DEHYDR_GLU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldehyde dehydrogenase" evidence="5">
        <location>
            <begin position="31"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="active site" evidence="3">
        <location>
            <position position="266"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009986"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OBZ85796.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="497" mass="54636" checksum="1CDC3437BCD95B3C" modified="2016-11-30" version="1">MSQTDLQSVHLANGKTIKVHTHLFVNNEFVAGHGPLIETINPANEQVICKVHSADENDVNKAVEAAHDCYYKTWRKMAPSERGLLMQKLANLMERDIDELATLDAVDNGKSFVVARDVDVTDSIACYRYFAGWADKIHGKTIDTTSDKMCYTRHEALGVVGAVIPWNYPTMMAAWKFAPALAAGNTIVMKSSEVTPLSTLKFAELVREAGFPPGVVNVITGYGHTTGAYLSSHPKISKMAFTGSTVTGRKIMEASAGSNIKKLQLELGGKSAQIICADADLENAAYWACGGIFNNHGQSCNAGSRIFVHESIHDRFLELFIAEAKKIKVGDPFKEDTFQGPQINKSQFDKILNYIEIGKKEGAKVAYGGKRWGEVGYYIEPTVLINCHNKMRIMREEIFGPVVAIGTFKTIDEAIDLANDSDYGLAGGVYTKDLDTAIMVTNEVKAGTMWVNCYDVFDQSTPFGGYKQSGFGKELGKYAIQEYTQVKVVKVMLQSKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-09-13" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NBT0</accession>
    <name>A0A1C7NBT0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">RxLR effector protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_05444</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000293">
        <property type="protein sequence ID" value="OBZ86511.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NBT0"/>
    <dbReference type="InParanoid" id="A0A1C7NBT0"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008889593" description="RxLR effector protein" evidence="1">
        <location>
            <begin position="21"/>
            <end position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ86511.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="73" mass="7834" checksum="F66E907FBD982B0F" modified="2016-11-30" version="1">MVRAALLISAIAALALTVSAEVKNNVVGAQVEHVAEDININRVVSGNDILNNANVKVLRRRSAARMLKRASQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NBT9</accession>
    <name>A0A1C7NBT9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">26S proteasome regulatory subunit 8 homolog</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">Rpt6</name>
        <name evidence="14" type="ORF">A0J61_05722</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">The 26S proteasome is involved in the ATP-dependent degradation of ubiquitinated proteins. The regulatory (or ATPase) complex confers ATP dependency and substrate specificity to the 26S complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 11">Belongs to the AAA ATPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000317">
        <property type="protein sequence ID" value="OBZ86229.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NBT9"/>
    <dbReference type="FunCoup" id="A0A1C7NBT9">
        <property type="interactions" value="254"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NBT9"/>
    <dbReference type="InParanoid" id="A0A1C7NBT9"/>
    <dbReference type="OrthoDB" id="1664597at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008540">
        <property type="term" value="C:proteasome regulatory particle, base subcomplex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd19502">
        <property type="entry name" value="RecA-like_PAN_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.60:FF:000006">
        <property type="entry name" value="26S protease regulatory subunit 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.140:FF:000044">
        <property type="entry name" value="26S protease regulatory subunit 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000030">
        <property type="entry name" value="26S protease regulatory subunit 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050221">
        <property type="entry name" value="26S_Proteasome_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041569">
        <property type="entry name" value="AAA_lid_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003960">
        <property type="entry name" value="ATPase_AAA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032501">
        <property type="entry name" value="Prot_ATP_ID_OB_2nd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23073">
        <property type="entry name" value="26S PROTEASOME REGULATORY SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17862">
        <property type="entry name" value="AAA_lid_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16450">
        <property type="entry name" value="Prot_ATP_ID_OB_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00674">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="12" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="14" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-0645">Protease</keyword>
    <keyword evidence="7" id="KW-0647">Proteasome</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="13">
        <location>
            <begin position="168"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="12">
        <location>
            <begin position="14"/>
            <end position="48"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006914"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00024661"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00069286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU003651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="OBZ86229.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="392" mass="43982" checksum="BA66EF06974B49E6" modified="2016-11-30" version="1">MKKEGVKSYYQAKIEECELIMNEKTQDLRRLEAQRNALNAKVRLLKEELQLLQEPGSYVGEVVKVMGKKKVLVKVHPEGKFVVDLASDIDIAQLTPTTRVALRNDSYQLHKVLPNKIDPLVSLMMVEKVPDSTYEMVGGLDQQIKEIKEVIELPVKHPELFESLGIAQPKGVLLYGPPGTGKTLLARAVAHHTDCRFIRVSGSELVQKYIGEGSRMVRELFVMAREHAPSIIFMDEIDSIGSARMESGGGGDSEVQRTMLELLNQLDGFEATKNIKVIMATNRIDILDPALLRPGRIDRKIEFPPPSEEARADILKIHSRKMNLTRGINLRKIAEKMSGSSGAEVKAVCTEAGMFALRERRVHVTQEDFEMSVAKVMKKDSDANTSLRKLWK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NBW8</accession>
    <name>A0A1C7NBW8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">BZIP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">A0J61_05362</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000287">
        <property type="protein sequence ID" value="OBZ86585.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NBW8"/>
    <dbReference type="FunCoup" id="A0A1C7NBW8">
        <property type="interactions" value="196"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NBW8"/>
    <dbReference type="InParanoid" id="A0A1C7NBW8"/>
    <dbReference type="OrthoDB" id="1939598at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001228">
        <property type="term" value="F:DNA-binding transcription activator activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000977">
        <property type="term" value="F:RNA polymerase II transcription regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd14705">
        <property type="entry name" value="bZIP_Zip1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.170">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004827">
        <property type="entry name" value="bZIP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046347">
        <property type="entry name" value="bZIP_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13044">
        <property type="entry name" value="ACTIVATING TRANSCRIPTION FACTOR ATF 4/5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13044:SF14">
        <property type="entry name" value="CRYPTOCEPHAL, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07716">
        <property type="entry name" value="bZIP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00338">
        <property type="entry name" value="BRLZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57959">
        <property type="entry name" value="Leucine zipper domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50217">
        <property type="entry name" value="BZIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00036">
        <property type="entry name" value="BZIP_BASIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="BZIP" evidence="8">
        <location>
            <begin position="211"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="195"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="232"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="195"/>
            <end position="214"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OBZ86585.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="274" mass="30651" checksum="19B0073F926E7FF5" modified="2016-11-30" version="1">MSYNPYNSYLSNLDSLVFDSPSEIIQSESEAAEELDLWSNAQFTFDMKPGVGIYDEEKKKSPMSLPANQFETASGGLDPVTYDTLANYLDYELPRQQAKMEQEQRKSSISSTPTMKKQRVIQPRPLAPALPTRTTPMLAPAPIVTPPVAIRQVLMPKPPTVPANILSDLLATAAQQSSTPSPVAASVLATAGVKRPIEESEKTEEGVTPDEDKRRRNTAASARFRIKKKMREQAMEQSVREMTMKSDKLQERVNHLEAEIKFLRNLLLDKTKQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NC29</accession>
    <name>A0A1C7NC29_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 9">Transaldolase</fullName>
            <ecNumber evidence="3 9">2.2.1.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">Taldo1_0</name>
        <name evidence="10" type="ORF">A0J61_05329</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Catalyzes the rate-limiting step of the non-oxidative phase in the pentose phosphate pathway. Catalyzes the reversible conversion of sedheptulose-7-phosphate and D-glyceraldehyde 3-phosphate into erythrose-4-phosphate and beta-D-fructose 6-phosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8 9">
            <text>D-sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate = D-erythrose 4-phosphate + beta-D-fructose 6-phosphate</text>
            <dbReference type="Rhea" id="RHEA:17053"/>
            <dbReference type="ChEBI" id="CHEBI:16897"/>
            <dbReference type="ChEBI" id="CHEBI:57483"/>
            <dbReference type="ChEBI" id="CHEBI:57634"/>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
            <dbReference type="EC" id="2.2.1.2"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 9">Carbohydrate degradation; pentose phosphate pathway; D-glyceraldehyde 3-phosphate and beta-D-fructose 6-phosphate from D-ribose 5-phosphate and D-xylulose 5-phosphate (non-oxidative stage): step 2/3.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the transaldolase family. Type 1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.2.1.2" evidence="3 9"/>
    <dbReference type="EMBL" id="LUGH01000284">
        <property type="protein sequence ID" value="OBZ86621.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NC29"/>
    <dbReference type="FunCoup" id="A0A1C7NC29">
        <property type="interactions" value="443"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NC29"/>
    <dbReference type="InParanoid" id="A0A1C7NC29"/>
    <dbReference type="OrthoDB" id="2015515at2759"/>
    <dbReference type="UniPathway" id="UPA00115">
        <property type="reaction ID" value="UER00414"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004801">
        <property type="term" value="F:transaldolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009052">
        <property type="term" value="P:pentose-phosphate shunt, non-oxidative branch"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00957">
        <property type="entry name" value="Transaldolase_TalAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.70:FF:000088">
        <property type="entry name" value="Transaldolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00492">
        <property type="entry name" value="Transaldolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001585">
        <property type="entry name" value="TAL/FSA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004730">
        <property type="entry name" value="Transaldolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018225">
        <property type="entry name" value="Transaldolase_AS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF009001">
        <property type="entry name" value="PRK12346.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00874">
        <property type="entry name" value="talAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10683">
        <property type="entry name" value="TRANSALDOLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10683:SF18">
        <property type="entry name" value="TRANSALDOLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00923">
        <property type="entry name" value="TAL_FSA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51569">
        <property type="entry name" value="Aldolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01054">
        <property type="entry name" value="TRANSALDOLASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00958">
        <property type="entry name" value="TRANSALDOLASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9" id="KW-0570">Pentose shunt</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0704">Schiff base</keyword>
    <keyword evidence="5 9" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00018292"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00048810"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU000501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OBZ86621.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="320" mass="35894" checksum="B9A1108E63A5B366" modified="2016-11-30" version="1">MTSVLDQLKQYTTVVADTGDFETIAEYKPQDATTNPSLILSASQKPEYAKLIDEAIAYGKKKGGSLDEQVNWAFDRLLINFGKEILKIVPGRVSTEVDARLSFDKDATVQKAIRLIELYKEEGVDKERVLIKIASTYEGIQAAHELETKHGIHCNLTLLFGFPQAVACAEAGVTLISPFVGRILDWYKNSTGKDYSGTEDPGVISVSKIYNYYKKFGYKTIVMGASFRNTGEIKELAGCDYLTISTKLLAELKNDTGKLERKLDPKGDKDLQKVSYFNDEKAFRWEMNQDAMATEKLSEGIRNFAKDGQKMEETLRSKMQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NCC5</accession>
    <name>A0A1C7NCC5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_05312</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000283">
        <property type="protein sequence ID" value="OBZ86648.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NCC5"/>
    <dbReference type="InParanoid" id="A0A1C7NCC5"/>
    <dbReference type="OrthoDB" id="2395010at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027850">
        <property type="entry name" value="DUF4504"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31366">
        <property type="entry name" value="UPF0739 PROTEIN C1ORF74"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31366:SF2">
        <property type="entry name" value="UPF0739 PROTEIN C1ORF74"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14953">
        <property type="entry name" value="DUF4504"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ86648.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="252" mass="28903" checksum="7C8D7E05BAAEA79E" modified="2016-11-30" version="1">MLIVDVLRPYFKSLNNSKLNILAKAIACVACGLRVSHLIDVAAIDQHKARQLLLALKKLPQCRTIALLQFKDRFSFICHSELLVQHVKSTLQCPDQLAFIAVEGKEPQPTEMPTCLTTWIRDKLCLSNAIYYSPIVPTFMVALTGWLLEYPIIYTTHLPTDDPEGELDEWEVRTNCLGNQPLQLTKVYLSHPDDIHLLMSFSSLAIQATSYIKPFELELKQRLVDAQKKFHWLRGYHINIAFEQIKLDRFAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7ND26</accession>
    <name>A0A1C7ND26_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Protein NRDE2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">NRDE2</name>
        <name evidence="5" type="ORF">A0J61_06673</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the NRDE2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000414">
        <property type="protein sequence ID" value="OBZ85274.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7ND26"/>
    <dbReference type="FunCoup" id="A0A1C7ND26">
        <property type="interactions" value="312"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7ND26"/>
    <dbReference type="InParanoid" id="A0A1C7ND26"/>
    <dbReference type="OrthoDB" id="297219at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071013">
        <property type="term" value="C:catalytic step 2 spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902369">
        <property type="term" value="P:negative regulation of RNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031048">
        <property type="term" value="P:regulatory ncRNA-mediated heterochromatin formation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006396">
        <property type="term" value="P:RNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003107">
        <property type="entry name" value="HAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013633">
        <property type="entry name" value="NRDE-2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13471:SF0">
        <property type="entry name" value="NUCLEAR EXOSOME REGULATOR NRDE2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13471">
        <property type="entry name" value="TETRATRICOPEPTIDE-LIKE HELICAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08424">
        <property type="entry name" value="NRDE-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00386">
        <property type="entry name" value="HAT"/>
        <property type="match status" value="9"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="222"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="17"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="39"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="60"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="105"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="222"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="237"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="257"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="270"/>
            <end position="280"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009265"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OBZ85274.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="1096" mass="127071" checksum="949CA8C6DF83765B" modified="2016-11-30" version="1">MSSSDNNKALTKRILVPPSFSSAPSFSSAPSFSSAPQLPKEDRKPDEKKRSRYDLDERRSHRHRDRSTSRRHRSRSPRSHRRSRSPSHRSSRSHRRSRSPSYRSSRSHHRHGSKRSSSPETVHTGTLNTGITFVMDRRGDPDIVTYGGNHIYSVPTFKRVGGGKVIGLPTYKRIDFSENKAGQIVLMDTLSRASKRYTDANYAWKELDKSFKRFRIKPTNTATDPFASSNPMIQLDDTVKPSKASEEDTYSMNVDYRSLEGNKTKSTHAEEDEMSEEEGAESFNDQIRRRTIQYNQQLDKDPTNPSLWLAFIRFQDEAARGLDPAAGSQKNRSSLTEIKLSIFEKALTHNPDSEELVLAYLTCGSETWETLRLLREWDQVLKDHPDSIRLWSEYINVRQTNFSSFSFTQCVQVFEDALDVLGRQAQQSRGERKEDIESIMVYILLRACLFMKQSGYQERAFAVIQAATEFNLFAPDPFQMAHSEAQKMKRFVDFWDSEVPRFGEKDALGWSEYDRMVANGDTIPDLPALQSDNGEDDDDDLMSLSDWLQAERLREDRQRLPLRMSQSDDNETDPFRIPLIEDVKSFLFSLRTPGARSSLIYSILVFLGLPYTPPEVGTNTHFFIDPFTHNEMPLVDFWPQEKDNQKHLVWYVDGVPMNPEDRSVVNHPYSIPNSYPIHVNELFAKYGSWFKASGKEFIRCQLDEQFTRHVFAKLLAVEKSEHLMICYLAFEASCGYKSGRRLAKSLLKDNGTNLKLWNAYAQMEKSHGRTEEARKVYMIALSMHHTLPESQQQSGVPLLYSMFAKLELENNRPNEALKILLCMPDNKSYDENTPLPSATSVLRAREYFSQKIAQLSILSEQDDERQASFYTTICYALFEYLTSGLSSAQTVYLHALKYIEERHAERGYASETLWIEYAALLYHDALSSAYKASTIRLAMEKALELFPNNTMFLAFYIWNESKTKIYNRVQQLLNEKQKDANIVLWLCTIYSELHRYRPYRADSVRSHFEKAVTHTRSSILLWKCYIEFEVKQNSIERAKSLFYRSIRECPWSKELYLLGIQLLEEIMTEKEKNELISLMMEKEIRIRVEIEQDLLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NDB6</accession>
    <name>A0A1C7NDB6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Kinesin-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">kif6_0</name>
        <name evidence="10" type="ORF">A0J61_04909</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="5">Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. KIN-13 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000251">
        <property type="protein sequence ID" value="OBZ87038.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NDB6"/>
    <dbReference type="STRING" id="101091.A0A1C7NDB6"/>
    <dbReference type="InParanoid" id="A0A1C7NDB6"/>
    <dbReference type="OrthoDB" id="3176171at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008017">
        <property type="term" value="F:microtubule binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003777">
        <property type="term" value="F:microtubule motor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007019">
        <property type="term" value="P:microtubule depolymerization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007018">
        <property type="term" value="P:microtubule-based movement"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01367">
        <property type="entry name" value="KISc_KIF2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.850.10:FF:000012">
        <property type="entry name" value="Kinesin-like protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.850.10">
        <property type="entry name" value="Kinesin motor domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027640">
        <property type="entry name" value="Kinesin-like_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019821">
        <property type="entry name" value="Kinesin_motor_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001752">
        <property type="entry name" value="Kinesin_motor_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036961">
        <property type="entry name" value="Kinesin_motor_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47971:SF20">
        <property type="entry name" value="KINESIN-LIKE PROTEIN KIF24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47971">
        <property type="entry name" value="KINESIN-RELATED PROTEIN 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00225">
        <property type="entry name" value="Kinesin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00380">
        <property type="entry name" value="KINESINHEAVY"/>
    </dbReference>
    <dbReference type="SMART" id="SM00129">
        <property type="entry name" value="KISc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00411">
        <property type="entry name" value="KINESIN_MOTOR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50067">
        <property type="entry name" value="KINESIN_MOTOR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 7" id="KW-0493">Microtubule</keyword>
    <keyword evidence="4 6 7" id="KW-0505">Motor protein</keyword>
    <keyword evidence="2 6 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Kinesin motor" evidence="9">
        <location>
            <begin position="141"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="463"/>
            <end position="503"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="56"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="469"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="482"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="230"/>
            <end position="237"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00061030"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00283"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000394"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50067"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OBZ87038.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="691" mass="78037" checksum="A10D3A69E1E0B34A" modified="2016-11-30" version="1">MSPPTVSPDRKSRRLTISQTPQRLPLTSPPSSNKMSARDRRLSYLPPPVARRESLFSKSPQLQRSPIRNGIKPTSPLQRKTQKSKSMIVEEERPSTRLLDAYGIPLQRPKSTAEPPTQSFEEFMAAKKTPKAPVSNELQQRIRVCVRKRPLNGREAVGQEDIAPLVGPRTIQVNAPKQRIDLTRYIEKHTFTFDEAFDVNTSNQQIYARTAKPLVDYVFTGGKATCFAHGQTGSGKTYTMLDPTHGLYVLAAQDIFRLLSTEHQDLVASVGFYEIYQGQLYDLLNNKQRLTARDDGNGNVVIAGLQEQVIRSVQDLKSVFEYGNAGRTTGRTGANSKSSRSHAVLQVLLRTRQTNKVYGKLSFIDLAGSERGADRGDGDTKTRLEGAEINKSLLALKECIRALDQNKNHTPFRGSKLTQVLRDSFTGNSRTCMIATISPNNANSEHTLNTLRYADRVKQLRGESDPRLANSSERISFVEQQKATEEEQGHEEEESKANDSQSITNSDAAIWEDEVSENLFEVDFPTEMATTNNNALATPNNDRYYEASPHRQEKYLKRLESPPAEVFSQPMEDPFFSKPIHPAKRPKQDNDEDSLYTRVRKFINLHRAQVQEMDGCIREEKKMIASLCLRVKSLYEIPDAFDHVGQVDDAQIRDEFESYLNDLDDILDRKQAVLSVVKGKLRDEFVEENAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NDJ3</accession>
    <name>A0A1C7NDJ3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 11</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">NDUFA11</name>
        <name evidence="7" type="ORF">A0J61_04800</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000242">
        <property type="protein sequence ID" value="OBZ87155.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NDJ3"/>
    <dbReference type="STRING" id="101091.A0A1C7NDJ3"/>
    <dbReference type="InParanoid" id="A0A1C7NDJ3"/>
    <dbReference type="OrthoDB" id="1913277at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045271">
        <property type="term" value="C:respiratory chain complex I"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006120">
        <property type="term" value="P:mitochondrial electron transport, NADH to ubiquinone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039205">
        <property type="entry name" value="NDUFA11"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21382:SF1">
        <property type="entry name" value="NADH DEHYDROGENASE [UBIQUINONE] 1 ALPHA SUBCOMPLEX SUBUNIT 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21382">
        <property type="entry name" value="NADH-UBIQUINONE OXIDOREDUCTASE SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02466">
        <property type="entry name" value="Tim17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="3" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="7" id="KW-0830">Ubiquinone</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OBZ87155.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="149" mass="15368" checksum="56D2D2C372394B12" modified="2016-11-30" version="1">MTASKDCLADAGKTAGIAGGVGLFVSAMQNTVQKHTSGARGVVTRTGGTIAFFAAMGGIFTLGECTARDMRQKEDPINAAIGGCAAGLLAGIKTHSFAKMGAGCAAIGATMYAYEASGQLKGQFANKTREEKKQYEKEFFKQPATAEEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NEH0</accession>
    <name>A0A1C7NEH0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">PHO85 cyclin-1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">PCL1_4</name>
        <name evidence="3" type="ORF">A0J61_04451</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000218">
        <property type="protein sequence ID" value="OBZ87502.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NEH0"/>
    <dbReference type="STRING" id="101091.A0A1C7NEH0"/>
    <dbReference type="InParanoid" id="A0A1C7NEH0"/>
    <dbReference type="OrthoDB" id="10250320at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000307">
        <property type="term" value="C:cyclin-dependent protein kinase holoenzyme complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016538">
        <property type="term" value="F:cyclin-dependent protein serine/threonine kinase regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019901">
        <property type="term" value="F:protein kinase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd20557">
        <property type="entry name" value="CYCLIN_ScPCL1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.10">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036915">
        <property type="entry name" value="Cyclin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006671">
        <property type="entry name" value="Cyclin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013922">
        <property type="entry name" value="Cyclin_PHO80-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15615">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15615:SF10">
        <property type="entry name" value="PHO85 CYCLIN-2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00134">
        <property type="entry name" value="Cyclin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47954">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cyclin N-terminal" evidence="2">
        <location>
            <begin position="118"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="65"/>
            <end position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ87502.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="276" mass="31905" checksum="884D22CE5AE88688" modified="2016-11-30" version="1">MMFISKEDRILFDQISRENVTSYILDFVSREYEAIIYCPPSRKSQKANTITQDIVEDYFSNKKKKDRHYKSRSNFDHSGLPSPPLSSSPERKSYRNTMTPTINYPPTPPDTPMPLRCYIESVVKKSGTSTGTLLTSLAYARRLRAKLSRTSKGMECTHHRIFLATLIVTSKYIHDSAIKNKYWVRYALQFFSASEINLMEKQLLHLLDYQLGVSPLEFDQIICDTLQLDAQYRQPGRSFIDFTEQAEYYYSYPTLSSNETSPSFISVELSNENSPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NEL7</accession>
    <name>A0A1C7NEL7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="10">MAP kinase kinase kinase wis4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">wis4</name>
        <name evidence="10" type="ORF">A0J61_04455</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000218">
        <property type="protein sequence ID" value="OBZ87498.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="FunCoup" id="A0A1C7NEL7">
        <property type="interactions" value="535"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NEL7"/>
    <dbReference type="InParanoid" id="A0A1C7NEL7"/>
    <dbReference type="OrthoDB" id="1043025at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0038066">
        <property type="term" value="P:p38MAPK cascade"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06626">
        <property type="entry name" value="STKc_MEKK4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050538">
        <property type="entry name" value="MAP_kinase_kinase_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48016">
        <property type="entry name" value="MAP KINASE KINASE KINASE SSK2-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48016:SF32">
        <property type="entry name" value="MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 10" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="9">
        <location>
            <begin position="951"/>
            <end position="1219"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="64"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="69"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="980"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OBZ87498.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="1323" mass="151092" checksum="43D5DE7AFD2072B0" modified="2016-11-30" version="1">MANVRRVHWTQHDNDMNEQHFAPESEDMQSNMPEGTSLIEPGFPNGYNTIPSWHFMNSYPTPISHNPYVDEDDYSDEDDQSNSDEDESAFNQLYARNQAVSAVSPEVSHERLEWQQMLQSVLLGEVIKSEKKRLSSSDKFALEKPTQEIWLSLRALLRGRTILQEQKSLEENRKEIDSVLEMVMEFKVEKNEQDAALRRVAEVLKNVDRIESLYTTRAELILAHPKYGSIEFQTKLDALNSWCTITRSLSMQYKILRNWTGSEDLQIARTRDTATENANDHKSDAAGRNDTSFVERLLKESALQDTFDKRTLSALNLLLLKSKETMIYNASQFREMNLPSFISQLRQLAYFPISLVEEALKLRLEYKNRMQEPPKQMVDTMMEDYRSLLSLACRVKRQYEELTNSAPGWKLDSDEPFDRNYDNVLMESVRFYFKLITWKLKLEKENNLREKEVMEKEWAFLQNTVCQVVDKADWECAEQFCSLTNRLLADVMNDYISSLKAPPESVDGGIEVKYTKLLHTMRMRARKLLQFARFFLSQFENSAEYVLDNDNMDKFVTCLVETGHFLVYTGSFEEDRVYIIASPSLYHRKDVIQTLIRSCFANSKAPQPSTPLISNELNIQNGDEDDYILIFSPWQNIMWTGEVVQVPTPFIHLGIKTKRVRLTTGDAQKLNSAKSTFWSAVQHSGIEIIQEHRAHIPRINKELYKIKMTVFKLADSTISSVGTIRDQTLSLGCQELVEECFSFASDFGIRASKFLELAVRLQLDLKLVRLAIDWICFITDDCIPSDRKTFRWAVAALEFVHMMTRGVNILALSENEFATLQSKVARCVALLISHFDVLGTRYTYELQLKEDQQRRRGLTAKRNSYMTSKSDKENITTSSTFGAANDAAITGGGGVIYIRDAWMRKIIELESKRTEDEQERKIIGKILDDQKPEDQSLVFLAPSSSNISFKWQQGRFIGAGTFGAVYLAINLDTSTVMAVKEIRFPDSSSLSALHKSIKEEMKVMEMLHHRNIVQYFGMEVHRDRVYIFMEYCENGSLGALLDHGGRIEDELYIVDYAYQLLSGLAYLHGNNIVHRDIKPDNILIDYQGQLKLSDFGAAKILAKGQKTMGRPTINMNVNSLAGTPMYMAPEVITGSNTGRKGSMDIWSLGCCIVQMATGRRPWSTLENEWSVMYHVVTGHPPLPDASQLSGPGIDFLKKCFVRDPNKRPSAEELLNHPWITSYLDSYSEEPQLPPPTQEGDPNDMLAHGDEQWINTAHNLSEYNGGNEIPPMVRSIGSVHSLERPLVRSIPNSLAIDGMTANHENGAKAQAYFQNIASQTSVNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NFK6</accession>
    <name>A0A1C7NFK6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_05842</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000327">
        <property type="protein sequence ID" value="OBZ86114.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NFK6"/>
    <dbReference type="STRING" id="101091.A0A1C7NFK6"/>
    <dbReference type="InParanoid" id="A0A1C7NFK6"/>
    <dbReference type="OrthoDB" id="20273at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="73"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="7"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="26"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ86114.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="223" mass="24640" checksum="208355E95DC91D15" modified="2016-11-30" version="1">MKETTVKDNNISKTLSNSSFTDTDNSESISSHSSYQQSNKKVPFSSAIDRLPQHDSLETIKTTRQKKDCGSHARLWVMLTFCVFVLGAIAAFVCMPRTPLVSMAGTAESLSGSPEWTSAPSMRATWRINVTLDNRTNWVPTHLTKLDFEMVDSLTLVRFAWATTGPIVLSPGSITPVSLVIHVNYQTADVTNPTFQNLYNACGPLSETKKEKPSLNVLLKARK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NG00</accession>
    <name>A0A1C7NG00_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Zinc finger matrin-type protein 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">Zmat2</name>
        <name evidence="7" type="ORF">A0J61_03994</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000186">
        <property type="protein sequence ID" value="OBZ87948.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NG00"/>
    <dbReference type="FunCoup" id="A0A1C7NG00">
        <property type="interactions" value="410"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NG00"/>
    <dbReference type="InParanoid" id="A0A1C7NG00"/>
    <dbReference type="OrthoDB" id="30343at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005681">
        <property type="term" value="C:spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046540">
        <property type="term" value="C:U4/U6 x U5 tri-snRNP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003604">
        <property type="entry name" value="Matrin/U1-like-C_Znf_C2H2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040107">
        <property type="entry name" value="Snu23"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45986">
        <property type="entry name" value="ZINC FINGER MATRIN-TYPE PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45986:SF1">
        <property type="entry name" value="ZINC FINGER MATRIN-TYPE PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12874">
        <property type="entry name" value="zf-met"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00451">
        <property type="entry name" value="ZnF_U1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="U1-type" evidence="6">
        <location>
            <begin position="93"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="26"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="149"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="26"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="56"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="177"/>
            <end position="186"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00451"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OBZ87948.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="214" mass="24911" checksum="A7AEB670854C2A4D" modified="2016-11-30" version="1">MSAYGAGKAKDTDFRRTWNKEEYAAKARAREERDRLAEKNEERKRQGLPPLKSHRKIEDDDKKEALKHREEKINLEKNVGKIQVVQAPDSRKQPGFYCKACDITIKDSVTYIDHLNGRKHLSNVGVSTKVEKASVDSVKDRLAMLKRKKENPQTEEYNLDERLAALKQQEEEERQKRRERKKQKKEGKKEDKEENDDDEMAKMMGFSGFGSSKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NG70</accession>
    <name>A0A1C7NG70_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_03846</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000175">
        <property type="protein sequence ID" value="OBZ88097.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NG70"/>
    <dbReference type="InParanoid" id="A0A1C7NG70"/>
    <dbReference type="OrthoDB" id="2250284at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="95"/>
            <end position="115"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ88097.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="249" mass="28674" checksum="1169C36461AF33C2" modified="2016-11-30" version="1">MSTTLIQEYPVCYAEAMDQSKETPFYIEWLDNTSEFPGLTPTTLGNEPWELLCRKEQEEHPTEEVGDWAKVAGQPQLYADITQKNAIQPTTRLVQSLWPHPPHKSKRPKKEEDREGLMDELGAELFYQHKAHSQRSNRLSRRRQHHDMETVRLNMEVVFHLATSKNGTVNIRCSSQELDPALLATLQESDLKDLRIHNKAQALSFVAKYKHNTKKYNAVYAGIGSKQPKRTDLYDASDLPVVKKEAYIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NGQ5</accession>
    <name>A0A1C7NGQ5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_03659</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000161">
        <property type="protein sequence ID" value="OBZ88292.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NGQ5"/>
    <dbReference type="STRING" id="101091.A0A1C7NGQ5"/>
    <dbReference type="InParanoid" id="A0A1C7NGQ5"/>
    <dbReference type="OrthoDB" id="2211259at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ88292.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="84" mass="9815" checksum="EBE56C59954A73ED" modified="2016-11-30" version="1">MVVKQSDTGSVRVRLKWDPQLLLQRKTQKTFMGTTRRVTTQMGTTAFNFAQPPKNTLTSTQSSIGYFVTKQYNEQFYFKQVRRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NGX1</accession>
    <name>A0A1C7NGX1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">dual-specificity kinase</fullName>
            <ecNumber evidence="2">2.7.12.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">pom1_1</name>
        <name evidence="13" type="ORF">A0J61_03549</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.12.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.12.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:10596"/>
            <dbReference type="Rhea" id="RHEA-COMP:10136"/>
            <dbReference type="Rhea" id="RHEA-COMP:20101"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:46858"/>
            <dbReference type="ChEBI" id="CHEBI:61978"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.12.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MNB/DYRK subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.12.1" evidence="2"/>
    <dbReference type="EMBL" id="LUGH01000155">
        <property type="protein sequence ID" value="OBZ88391.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NGX1"/>
    <dbReference type="FunCoup" id="A0A1C7NGX1">
        <property type="interactions" value="173"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NGX1"/>
    <dbReference type="InParanoid" id="A0A1C7NGX1"/>
    <dbReference type="OrthoDB" id="9332038at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005856">
        <property type="term" value="C:cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004712">
        <property type="term" value="F:protein serine/threonine/tyrosine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd14210">
        <property type="entry name" value="PKc_DYRK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000112">
        <property type="entry name" value="Putative dual specificity tyrosine-phosphorylation-regulated kinase 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.10.30">
        <property type="entry name" value="DYRK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042521">
        <property type="entry name" value="DYRK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050494">
        <property type="entry name" value="Ser_Thr_dual-spec_kinase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24058">
        <property type="entry name" value="DUAL SPECIFICITY PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24058:SF22">
        <property type="entry name" value="DUAL SPECIFICITY TYROSINE-PHOSPHORYLATION-REGULATED KINASE 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 13" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="12">
        <location>
            <begin position="762"/>
            <end position="1058"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="133"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="264"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="494"/>
            <end position="629"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="641"/>
            <end position="660"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="997"/>
            <end position="1018"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="17"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="133"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="159"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="176"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="189"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="265"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="351"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="503"/>
            <end position="520"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="578"/>
            <end position="592"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="604"/>
            <end position="624"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="998"/>
            <end position="1008"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008867"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00049003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00049308"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00051680"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="OBZ88391.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="1064" mass="119614" checksum="EC15F57826F807E3" modified="2016-11-30" version="1">MQVPTTKKSAEFDTIPVPSNSSSFSTLSQEPWNKVQSSYTAKRKQMQEERLRQLKELEEQVTDTANWNQRRRVLTISTSHLSVSEDNSILYPASNTPSPIIKSNNKVDLGEATLEDLEDLIAASAKRLASYRLRNSNHQLPNQKSPSPTARSNTKKKSTGQDELNRWKELLDHRLSSSSLSDQSSPVSANPSTTINPNMTDNVTIQGERNPSASYQRLRNMFEKDKDRNKNTLLSSKAVQQQQEQEILPTRTKKVSSFSLADLAHTTPSSSSSSSSSHHKSVTSPSYSNWKHGNGIHTTRSTVANAAPKIEPPRISASTTPRVPQLRKATRSYSHQRLAEPSSIPTSTSFEPKRTEPAVTRSETRRTLASLMRERNQKLNTKGSGTHSDDRDKLYEDDDAANDSQTTASQTRRRVKLSITASNTSSLLSQKSTSKLNPTAPTAIPSDAVIKRKRVKTLPGKLIVQPSIAPLSLPPMKVEPLNIPLVKNSRTVAKTPTRIPLPSSASTSTTNNNNNNNNSTPRIVYRRNNDTTEYNTSSDDDHHQHQKKLSSSYSRGKPISTAGSTASTKQLRKPKSTLAVSNTPKLRSSKSNKSTDDCSLRKNTLLTPSSSTTTDSSLSSTAASKSKRKTLALHERLQGLLDVSNSHSKTHEGQSSEVVIRGRGISTSASAPAIHIANGDEDKQPKVMMRVAMTPEAAQKLYQFNLTSYEKQEMMAYEHIYFVGHHAKKRPASPSNSNCNYGYDDERGDYLIQLRDHLDYRYEVLEVMGKGSFGQVLKCFDHRSGQTVAVKMIRNKKRFHAQAMVEVKILEDLMAWDPEDEHNNLRMLGHFMFRNHLCIVSECLSMNLYEFIKSNGFMGFSIGLIRRFATQLLKSLMLLQEHKLIHCDLKPENILLKHPTKSTIKVIDFGSSCLETEKVYTYIQSRFYRSPEVILGMSYSMAIDMWSFGCILAELHTGYPLFPGENEQEQLACIMEIQNVPEPYIIEKSSRRKLFFDSQGNPRIQPNSKGRKRRPGTKSLREVLRSTDELFVDFVGQCLQWDPEQRLKPSDALNHPWIKNHRRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NH28</accession>
    <name>A0A1C7NH28_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Nudix hydrolase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">A0J61_03892</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000178">
        <property type="protein sequence ID" value="OBZ88059.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NH28"/>
    <dbReference type="STRING" id="101091.A0A1C7NH28"/>
    <dbReference type="InParanoid" id="A0A1C7NH28"/>
    <dbReference type="OrthoDB" id="2011998at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034431">
        <property type="term" value="F:bis(5'-adenosyl)-hexaphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034432">
        <property type="term" value="F:bis(5'-adenosyl)-pentaphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008486">
        <property type="term" value="F:diphosphoinositol-polyphosphate diphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000298">
        <property type="term" value="F:endopolyphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901911">
        <property type="term" value="P:adenosine 5'-(hexahydrogen pentaphosphate) catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901909">
        <property type="term" value="P:diadenosine hexaphosphate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901907">
        <property type="term" value="P:diadenosine pentaphosphate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071543">
        <property type="term" value="P:diphosphoinositol polyphosphate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.79.10">
        <property type="entry name" value="Nucleoside Triphosphate Pyrophosphohydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015797">
        <property type="entry name" value="NUDIX_hydrolase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000086">
        <property type="entry name" value="NUDIX_hydrolase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12629">
        <property type="entry name" value="DIPHOSPHOINOSITOL POLYPHOSPHATE PHOSPHOHYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12629:SF0">
        <property type="entry name" value="DIPHOSPHOINOSITOL-POLYPHOSPHATE DIPHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00293">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55811">
        <property type="entry name" value="Nudix"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51462">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nudix hydrolase" evidence="4">
        <location>
            <begin position="86"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="47"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="68"/>
            <end position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OBZ88059.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="219" mass="24879" checksum="8E973CF3CE7BB40F" modified="2016-11-30" version="1">MATAMTASTLDSTKFEPTPNKLITDKPLEVPGEPVIADEDRLEKKDKKDKKDKKDKKDKKDKKKDKKKEKIKDKKKKEDALEQAKPVRQAVGVIVIDSATQKILLLESQKRPGAYVLPRDDCLPDEHPEKAAIRLLAEKAGIQTAFLSCRVGSYSETNKKGRITDQHWMYEVNSYSLLPSNRQRSWFTYEEALEVLKEKKISHLALEKCTLATQPVTTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NHT5</accession>
    <name>A0A1C7NHT5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">receptor protein-tyrosine kinase</fullName>
            <ecNumber evidence="2">2.7.10.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">A0J61_05041</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.10.1" evidence="2"/>
    <dbReference type="EMBL" id="LUGH01000262">
        <property type="protein sequence ID" value="OBZ86904.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NHT5"/>
    <dbReference type="InParanoid" id="A0A1C7NHT5"/>
    <dbReference type="OrthoDB" id="2289488at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071944">
        <property type="term" value="C:cell periphery"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004714">
        <property type="term" value="F:transmembrane receptor protein tyrosine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.2930">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044912">
        <property type="entry name" value="Egfr_JX_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051694">
        <property type="entry name" value="Immunoregulatory_rcpt-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049328">
        <property type="entry name" value="TM_ErbB1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15549:SF26">
        <property type="entry name" value="AXIAL BUDDING PATTERN PROTEIN 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15549">
        <property type="entry name" value="PAIRED IMMUNOGLOBULIN-LIKE TYPE 2 RECEPTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21314">
        <property type="entry name" value="TM_ErbB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0418">Kinase</keyword>
    <keyword evidence="10 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="5 13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 13" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="11" id="KW-0829">Tyrosine-protein kinase</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="83"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="domain" description="Epidermal growth factor receptor-like transmembrane-juxtamembrane segment" evidence="14">
        <location>
            <begin position="86"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="224"/>
            <end position="248"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011902"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF21314"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="OBZ86904.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="248" mass="27076" checksum="B91D0D680305B2B7" modified="2016-11-30" version="1">MVVVLPSRTSDSVNMAYNKRQQPSESVVHVTITAAGTVVYTYTATSYSYIPSYSTISTSNPSMTNSNNNGNNGSSGSHNNSNIGAIAGGVVGGVVFVALIALLFLFLRRQSQKRKREKQKNELIDDDDDSYYRGLNGRPLSAASVDHTNPAVMTSLNSPRPLVAPEGLRESKYFQGDGYYEDRLAPYPKAAAYYSANNSVASDSLPSTAVDINGGYRNVPNEIEHFPEERHVPHLKESSREEPPHARD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NIH5</accession>
    <name>A0A1C7NIH5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_03030</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000124">
        <property type="protein sequence ID" value="OBZ88912.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NIH5"/>
    <dbReference type="STRING" id="101091.A0A1C7NIH5"/>
    <dbReference type="InParanoid" id="A0A1C7NIH5"/>
    <dbReference type="OrthoDB" id="2221171at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015074">
        <property type="term" value="P:DNA integration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.443.10">
        <property type="entry name" value="Intergrase catalytic core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011010">
        <property type="entry name" value="DNA_brk_join_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013762">
        <property type="entry name" value="Integrase-like_cat_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35617:SF3">
        <property type="entry name" value="CORE-BINDING (CB) DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35617">
        <property type="entry name" value="PHAGE_INTEGRASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56349">
        <property type="entry name" value="DNA breaking-rejoining enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="30"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ88912.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="448" mass="49803" checksum="EFF6136764CA8084" modified="2016-11-30" version="1">MENIQTDTTQIRTSDNGCICIAPEHQTPAFLESTTGSGGTGDGRTPSAVATQGPLPIPTVEVDPESPPKDETREVAVSSTDLTVLANSTLVSHVAADEPTFLPITISNGQVENGRLETIREKRKEQGITETSCSQQTPQIDPKEYNPLAVLQFLTDNRSYAYSALNGFRSSIASKLQEVRTPSASQLKTWDTDIMVSYIHQNYASSENLSLYELQQKTVLLFCLSTMARPRSDVERLQFRDVLFDLSQDKPVSLTLHFREAKETQVKTCTLGLIEVEELCPVRTAYLFTEKSKPLRVLLPADHTYFLAHIDDLEQVNSIRPSTLSSWIKTSMQKAGIDTKTYKPHSVRSASSTKAVEKGSSVDAVKQHANWSLHSNTFEKHYYKPIAQQASSTQIANSIFSTENNTTLEVGVKSTRIALGTTSNTDVDETKTENVVHTRPSFWSRFFW</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NIU9</accession>
    <name>A0A1C7NIU9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Carbohydrate-binding module family 19 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_02996</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000122">
        <property type="protein sequence ID" value="OBZ88955.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NIU9"/>
    <dbReference type="InParanoid" id="A0A1C7NIU9"/>
    <dbReference type="OrthoDB" id="2287982at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008889723" description="Carbohydrate-binding module family 19 domain-containing protein" evidence="1">
        <location>
            <begin position="17"/>
            <end position="137"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ88955.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="137" mass="14693" checksum="5734AF410094A829" modified="2016-11-30" version="1">MRLFVYGCVLLAVVDCFSIQDASVSSSIGSALPEFSIVAQNGNIPAADIFQPQANIETLSENIKRPMFEANSYVKLPNGNWAPSCKHVTEGTYCLKPDGEDASIVQCLGENVGFQFQCANGMKCYSAGPTDVDCIKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NJT6</accession>
    <name>A0A1C7NJT6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Cardiolipin synthase N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">A0J61_03194</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000133">
        <property type="protein sequence ID" value="OBZ88756.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NJT6"/>
    <dbReference type="InParanoid" id="A0A1C7NJT6"/>
    <dbReference type="OrthoDB" id="5193244at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027379">
        <property type="entry name" value="CLS_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13396">
        <property type="entry name" value="PLDc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="6"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="41"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="domain" description="Cardiolipin synthase N-terminal" evidence="7">
        <location>
            <begin position="19"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF13396"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OBZ88756.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="73" mass="8361" checksum="0C475FCC27A73D06" modified="2016-11-30" version="1">MYDTVLSYSGGFLGLLVLILDLIVIFEVMNSNRNVSGKLGWSLLVFFFPVVGLILYFLFSDRNEHNARYEPII</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NK22</accession>
    <name>A0A1C7NK22_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">DNA polymerase V</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">pol5</name>
        <name evidence="4" type="ORF">A0J61_02609</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the MYBBP1A family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000100">
        <property type="protein sequence ID" value="OBZ89348.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NK22"/>
    <dbReference type="FunCoup" id="A0A1C7NK22">
        <property type="interactions" value="509"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NK22"/>
    <dbReference type="InParanoid" id="A0A1C7NK22"/>
    <dbReference type="OrthoDB" id="342531at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000182">
        <property type="term" value="F:rDNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007015">
        <property type="entry name" value="DNA_pol_V/MYBBP1A"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13213:SF2">
        <property type="entry name" value="MYB-BINDING PROTEIN 1A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13213">
        <property type="entry name" value="MYB-BINDING PROTEIN 1A FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04931">
        <property type="entry name" value="DNA_pol_phi"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006809"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OBZ89348.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="1120" mass="127364" checksum="3468ED904F8EDC1B" modified="2016-11-30" version="1">MATTTLQLYWDLASFDPNARQIAAHSLIKTLAEFQKAHEETLESKDIADTEEKLDLLCASDVSYAVRRLLRGLPSSRQGARQGFSLALTELLAIVDLIATKLVLDLLFKYTERTGSMSGDETRDMLFGRLFGLMSVVAAGMISRASTSTEDVLRIIESLHEMATSKSYLAEVCHHVVINMLPYLKSSDHQEQAAEKIKELFLKGQITNVDQLNLVVGIQQKLDNVDLSEQFANWKSSTILDPVNLNMLANILKEIPSDTQEALADWKPQLHSVWDPLLAVYFEKKQPKKIATFQEFWTAAVDSTMFDLNASHGRKYWGFQLVEKVLRRLSPEQMPLIFTANFMRTFINNLSSEDRFLNKAARHTAQVIQSVAEDNKQVGFALITQLLGKNGHQNFDRITRTKTVENLLTTLDTEGIKSYLEYLAQTFVKSNGDENSSITSREWALNQMTLLITNTKIPKEEGWVIELVQFMMTHAFFDVKTADKAKSYLTGLFKPTPSLSEASVNACQERFQNVLVALSKLPPLKQLQQADAPIKSRKLHGITNEGELWAYQVFQIYQSLEKNKKLVLRVTPSDKTTEATEKAVKIVQELRTKITKLDKTEAHDSVERGFEILFLNIVLHTLFNESEATSVLTELIDCYEKTSVKKAPKKKGKKTKKEEEEEQLDPIDVIVDILVSFLTNESPVLKNLAEQVFEIFSHKLTKQSLEMLLNILASGDDKQADDLFGDDEDEDDDDVEMLDMDDIEDIEEDDEEEDEEVDEELRQKIEEAMKAQGIHADDESDEDLDDDAMAAFDEKLAEVFRQKKIAKNEKTTVQQNVVHFKNNVMGLVVIYARKNPTNPLVLSLIVPLLNIIRATPAKSVTNQFVEKIIAFLKNRLAKSTQYPKEQSDYVFDILQAVHDFAKHSTSKELSEMCNQLSMYLRKCILGGFDFELNNDTSAKTNQAVEKYIAIYKDSAKLYLTKKSTSFHPSIIQQMIQRYPLSSWDILDTLADFVDRSHCANIYRLSMACKWITIIIQRTVGKNSEVYNQKYLTIVPKFAKSVKTTIELSLKEQDKGLDYEGMKNYLRFVTLLVRLHKKVAPETIDLKNTWDAELISSIPSNDKFSKPSISSLVKSLEPLWV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NKB4</accession>
    <name>A0A1C7NKB4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_02508</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000095">
        <property type="protein sequence ID" value="OBZ89448.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NKB4"/>
    <dbReference type="InParanoid" id="A0A1C7NKB4"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="46"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ89448.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="66" mass="7727" checksum="16CD3D5C063F7990" modified="2016-11-30" version="1">MAMKSVAQLLDSSLVLLLHLLSFEMNLFYEDGRVWIMDDFDNKAIALFFVVMCFQLANLIDLYNYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NKU2</accession>
    <name>A0A1C7NKU2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Transmembrane GTPase fzo1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">fzo1_1</name>
        <name evidence="8" type="ORF">A0J61_04025</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000188">
        <property type="protein sequence ID" value="OBZ87924.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NKU2"/>
    <dbReference type="FunCoup" id="A0A1C7NKU2">
        <property type="interactions" value="49"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NKU2"/>
    <dbReference type="InParanoid" id="A0A1C7NKU2"/>
    <dbReference type="OrthoDB" id="9984778at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005741">
        <property type="term" value="C:mitochondrial outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008053">
        <property type="term" value="P:mitochondrial fusion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051646">
        <property type="term" value="P:mitochondrion localization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045063">
        <property type="entry name" value="Dynamin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030381">
        <property type="entry name" value="G_DYNAMIN_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027094">
        <property type="entry name" value="Mitofusin_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10465:SF0">
        <property type="entry name" value="SARCALUMENIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10465">
        <property type="entry name" value="TRANSMEMBRANE GTPASE FZO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00350">
        <property type="entry name" value="Dynamin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51718">
        <property type="entry name" value="G_DYNAMIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0812">Transmembrane</keyword>
    <feature type="domain" description="Dynamin-type G" evidence="7">
        <location>
            <begin position="70"/>
            <end position="330"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51718"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OBZ87924.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="657" mass="75483" checksum="021476EC04C4922F" modified="2016-11-30" version="1">MTDPLTITPNQHQTEQFCQSPTALWSGEDYQTSTEAILQSIALVKQLLAEQPQLCQQDHSQLDIWAQRLLNSSSKILVTGDLNSGKSTLVNALLKTPDLLPVDQQPCTSMFCQVVNAPQQKDPLLHAFNDIHLYQPQDPTTYTVVPFHELYNLLTLEEPPFKVLRLYTDLTPYPSLIAHHQITLIDSPGLNTDSIRSTTEFAQEEEMDAVVFVVNAENHFTLSGRAFLQSITQPNVFIAVNKFDHIRDKERCKRLILEQIRDVSPLLYEQADQLVHFVSAAYGADATDFMQLEESLCRFVLQIRLESKLLPVQKSLVEYTRTLVTQAKQQADQTQSQLGQLESEFTLFLEDYARLVEAQHQVKHTFHPLIQQTVKETRQTLIRTLDSSSLYDVIQEVNYQGIHHIWSYAQTMSQVLNTHLNQRLIWMEQEANRQTETCRHQMHQLITEQVGHQYPWVSEKQQLKGSQERTEVDLQVQLSDLLCNKMDDKKLGLTTASLAILLLETETLQQQAVYWLTRLLKPVVAHSSHQYARRAIGWSLTCISLVSVGWTAYAFLSDMPGAVQMNLKHKFESAMERAQVQQRANTLTDQVQHLLEIEQTEWLCQLGQWISVKDKERARLEQNLFESKQKAHQLTTWLSRSNTILHDIENLPILSKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NLH0</accession>
    <name>A0A1C7NLH0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Telomere length regulation protein TEL2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">Telo2</name>
        <name evidence="7" type="ORF">A0J61_03795</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TEL2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000171">
        <property type="protein sequence ID" value="OBZ88164.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NLH0"/>
    <dbReference type="STRING" id="101091.A0A1C7NLH0"/>
    <dbReference type="InParanoid" id="A0A1C7NLH0"/>
    <dbReference type="OrthoDB" id="10258062at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051879">
        <property type="term" value="F:Hsp90 protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042162">
        <property type="term" value="F:telomeric DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051083">
        <property type="term" value="P:'de novo' cotranslational protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.720">
        <property type="entry name" value="Telomere length regulation protein 2, C-terminal domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038528">
        <property type="entry name" value="TEL2_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051970">
        <property type="entry name" value="TEL2_Regulation"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057348">
        <property type="entry name" value="TELO2_ARM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019337">
        <property type="entry name" value="Telomere_length_regulation_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15830">
        <property type="entry name" value="TELOMERE LENGTH REGULATION PROTEIN TEL2 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15830:SF10">
        <property type="entry name" value="TELOMERE LENGTH REGULATION PROTEIN TEL2 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25320">
        <property type="entry name" value="TELO2_ARM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10193">
        <property type="entry name" value="Telomere_reg-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TELO2 ARM repeat" evidence="6">
        <location>
            <begin position="320"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="domain" description="Telomere length regulation protein conserved" evidence="5">
        <location>
            <begin position="535"/>
            <end position="645"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="462"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="496"/>
            <end position="528"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="466"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="501"/>
            <end position="523"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF10193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF25320"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OBZ88164.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="823" mass="93997" checksum="A1DACC3F96BA7124" modified="2016-11-30" version="1">MTSLETLLDQLNDLDHQTSEPNCSLDTVLLCLSTPLDWLEDQDRPLTSKRALVQHSTWKRHLWHLCETIVPHWMFSLSLPEHRKRLEASWGYAADTHDQIKVMMIQASLPILLECLSRQDHASLETLEAYASFLQSISLSHSVFCLYGNYISKTDVSFFCSLVCSIPSHLNNAFAIQFDRVRFNSEHAWYIDRHYYAKMSSRAAKYLTDKSSVFTHALLGKMIRQGYEVARLNPDHWPCVFEQIELIASYEQVNRALLHYVHDHIVLPNSMSVASASKELASLLFGTESDCKEQRLSAFLNTAIFRLSKSSWADSLLARISISTVIHHLAEDRRLPFLDSIIRRVIQTWSDPVFIQHASSRERLYMTTALLSLIAYLSNDDIQHTIMAETPLFHHVSTYFNSGDIQIAQLGAVVAEALSSRIDKEKPLNTTLLDSNPSLQELKGLVWITDAYDEPTACSVTMTPEAESEDETEETEELDPDADITLVLDRVVADMSHDIEDSNDEEEEEFEPYDMEEESEDEGLTNKEIKQTKKPVFIRDLIRCLQDRDDPLKLEIGLTAAEQVIRRKTGAGTELSESSINLARYLIGFPETYEIHDFRKLQQQALVALIVGVPESVTEFIIDQLYDRNTSTGQKQMILGAISSAVRELAGWSESDNTPELQIDQPQAGKQLFVSRRMEIERQNQHKIKRNRLSGLAGPVFFFPLLVGWWEGSQGHLSYWMGSSALLTERFVMTLNVILYSSNNLTYQTRIANTLDKRKIVKEYFEFALSMQYAAHLSVGTKRALLLGIDTIISICYQHQEKLLFSDYTKELVETKQWLEGNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NLJ3</accession>
    <name>A0A1C7NLJ3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_01964</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000069">
        <property type="protein sequence ID" value="OBZ89977.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NLJ3"/>
    <dbReference type="InParanoid" id="A0A1C7NLJ3"/>
    <dbReference type="OrthoDB" id="10443951at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="48"/>
            <end position="69"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ89977.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="73" mass="8260" checksum="B2E42894740FCF37" modified="2016-11-30" version="1">MSDLSFTRSVEKKLCMQNQTTFVFSNKGSGLPTQTYVKNERLQPESPYIKSGLSLVAFILTTILVNSLLEWTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NLU4</accession>
    <name>A0A1C7NLU4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Elongator complex protein 4</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">elp4</name>
        <name evidence="10" type="ORF">A0J61_01898</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="3">tRNA modification; 5-methoxycarbonylmethyl-2-thiouridine-tRNA biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the ELP4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000066">
        <property type="protein sequence ID" value="OBZ90035.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NLU4"/>
    <dbReference type="FunCoup" id="A0A1C7NLU4">
        <property type="interactions" value="636"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NLU4"/>
    <dbReference type="InParanoid" id="A0A1C7NLU4"/>
    <dbReference type="OrthoDB" id="289162at2759"/>
    <dbReference type="UniPathway" id="UPA00988"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033588">
        <property type="term" value="C:elongator holoenzyme complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008023">
        <property type="term" value="C:transcription elongation factor complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002098">
        <property type="term" value="P:tRNA wobble uridine modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd19494">
        <property type="entry name" value="Elp4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008728">
        <property type="entry name" value="Elongator_complex_protein_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12896:SF1">
        <property type="entry name" value="ELONGATOR COMPLEX PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12896">
        <property type="entry name" value="PAX6 NEIGHBOR PROTEIN PAXNEB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05625">
        <property type="entry name" value="PAXNEB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0819">tRNA processing</keyword>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="375"/>
            <end position="434"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007573"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00020265"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OBZ90035.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="434" mass="48144" checksum="74E7CAC212053EE3" modified="2016-11-30" version="1">MSFKKRNADQQPKLPSGSRLSAYNGQLLVSTGVPSLDDILGGGQPVGTIMLIKEDRATTYAQLLLKYFMAQGISSGHHCAIASRDEDPEEMLKTLMWLSTSDRDNDDEDESDKAKNALDADNDRMKIAWRYSHLKRFETGVKPKQPSPILSTPIVHKETNTTEEPKPYCSQFDLTKRIPADILEKASTEIVRWTHESDEKDDHDDYAILLDKIRQIVVDGQFSSTKPVAPGTVRNALRVGIHSLASPSWQSESPNNIYQFFHALRGLLRFSFGTALVTVPAYLYDEVPNFMKRIEHMVDAVIEIESFAGDPIHNEAAYTQNYHGFFHVHKLPVLNSLLPPSTKLSVLSAGGSNDLGFKLRRKRFAIETFHLPPEGGVVTRRTEPPAVSEPTVKSSKKETSSSSSQLGLASLANRNGPKKIGCGSTPGKIDPLEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NM38</accession>
    <name>A0A1C7NM38_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_01773</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000060">
        <property type="protein sequence ID" value="OBZ90182.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NM38"/>
    <dbReference type="InParanoid" id="A0A1C7NM38"/>
    <dbReference type="OrthoDB" id="2366000at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="43"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="43"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="71"/>
            <end position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ90182.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="81" mass="9233" checksum="6F870937ED940F78" modified="2016-11-30" version="1">MSHFEKETVYEVVLDAHGVAQRVPKGQGTHIIHVSANKETRLEEKTEFNADKWKQTTPTYSKRIHPTTETTPKEEVEKTGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NM40</accession>
    <name>A0A1C7NM40_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Sister chromatid cohesion protein pds5</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">pds5</name>
        <name evidence="8" type="ORF">A0J61_02018</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000071">
        <property type="protein sequence ID" value="OBZ89929.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NM40"/>
    <dbReference type="FunCoup" id="A0A1C7NM40">
        <property type="interactions" value="609"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NM40"/>
    <dbReference type="InParanoid" id="A0A1C7NM40"/>
    <dbReference type="OrthoDB" id="200660at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000785">
        <property type="term" value="C:chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007064">
        <property type="term" value="P:mitotic sister chromatid cohesion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd19953">
        <property type="entry name" value="PDS5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039776">
        <property type="entry name" value="Pds5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12663">
        <property type="entry name" value="ANDROGEN INDUCED INHIBITOR OF PROLIFERATION AS3 / PDS5-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12663:SF0">
        <property type="entry name" value="PRECOCIOUS DISSOCIATION OF SISTERS 5, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20168">
        <property type="entry name" value="PDS5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="2" id="KW-0132">Cell division</keyword>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0498">Mitosis</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1118"/>
            <end position="1141"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="38"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="1118"/>
            <end position="1128"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="1130"/>
            <end position="1141"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OBZ89929.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="1141" mass="129276" checksum="C5B7054C086D022C" modified="2016-11-30" version="1">MDIDDPTNTQTSELLDSQMTEESPVLDFSESLLSTKKAAELKGLLQNLHEQLKELDQNVDKSSLESVTQELVHKNIMKNKDKTVKALAACCLADIIRLHAPESPYSIDVLRTIFVFFVDELSHFGKEAAEFPYYFYLLENLQSVKTFLLLNDIDNVEEIVLPLIVEFFKVAQTGSLARNVELCMTDVLIQLIDDVGISSPEFTEIILEQFDNFEKGSKNSAYVMALDICYTCPGALQRRVFQYFSDVLISVSTAEESEEDYAEVKKAHNLICKINAVVPELLMNVLPLLQEEMKVDHINIRQLSTETLGRMFAEPSSSVATQYPAIWKTWLGRRHDKSIQLRVKWLEMSVDIFKHHASAVAELIECYKDRLFDPDERVRAAACRAIGEVSIGQDIKNLDRRLLEMISERSKDKKTSVRVEAMKTFGSVYNHYYAQINAHDKTVMDKVGWIADRLMYCLYLGNPAVTMNLESTLLTYILPENENDAERTERLIVVLESFAEKQKLAFTALVRKQKMFNDNLHKYIDMCEKAISSKGNLSEHEEAKNDEFMKYLAGQFADKARTLNALRTFLQSGNDKDVKALKTAVDLNRTYKQVLAAKKKLVSSLNEEHAAILEIFQAILNRACPLIINKSNIPHLLKLSRTVRSRRQTVASQRATVAQDVLKEISTTYPSMYTSNMADIMKEILASNENSDEALELLAEVSKESNGKMKYSDELSNCLINYMREGDTNQAHYASVALSNMKNADVALAELVSRMCDELLLKNHRLLSTLTSLSNFALHAHDLVSTSLDSVIRFVESVLLVAKTKEFSSDNPEWEAYDDLPELSKQKLVGVRLLVNYLTACKEDVGPEEYIIQKIFGLLENLLDLSCDQAFSTKTNAAETSHLRLGASRALVKLTQHAKYVNQLTVPKFEKLGITLQDTCFYVRQEFAESLMKGLHTEQIHSRYYALLFMCAHEPEAALVKQVKGFIQKKLSSIQSKQGDANVLDSALIRLIHLLAHHPDFSEAVEDLEVLAQYFRFYLACVATSDNVAFLYHIVQKIKLSTDTISAEMSKNSYILSDLACLLIKTRCKEASWPLNAYAGRVSLPTRLYQLIPEGAVQSEIMNQTYLPAEFLEKYEEEQNHKAGDKRSRFSTTVSSKKVKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NM55</accession>
    <name>A0A1C7NM55_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">ATP-dependent DNA helicase</fullName>
            <ecNumber evidence="9">5.6.2.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">pif1_4</name>
        <name evidence="12" type="ORF">A0J61_01836</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="5.6.2.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="9">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the helicase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.6.2.3" evidence="9"/>
    <dbReference type="EMBL" id="LUGH01000063">
        <property type="protein sequence ID" value="OBZ90108.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NM55"/>
    <dbReference type="STRING" id="101091.A0A1C7NM55"/>
    <dbReference type="InParanoid" id="A0A1C7NM55"/>
    <dbReference type="OrthoDB" id="5578775at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043139">
        <property type="term" value="F:5'-3' DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000723">
        <property type="term" value="P:telomere maintenance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd18809">
        <property type="entry name" value="SF1_C_RecD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.940">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010285">
        <property type="entry name" value="DNA_helicase_pif1-like_DEAD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049163">
        <property type="entry name" value="Pif1-like_2B_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051055">
        <property type="entry name" value="PIF1_helicase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47642">
        <property type="entry name" value="ATP-DEPENDENT DNA HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47642:SF5">
        <property type="entry name" value="ATP-DEPENDENT DNA HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05970">
        <property type="entry name" value="PIF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21530">
        <property type="entry name" value="Pif1_2B_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 9" id="KW-0227">DNA damage</keyword>
    <keyword evidence="9" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="7 9" id="KW-0234">DNA repair</keyword>
    <keyword evidence="6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4 9 12" id="KW-0347">Helicase</keyword>
    <keyword evidence="3 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-0413">Isomerase</keyword>
    <keyword evidence="1 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA helicase Pif1-like DEAD-box helicase" evidence="10">
        <location>
            <begin position="36"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="domain" description="DNA helicase Pif1-like 2B" evidence="11">
        <location>
            <begin position="218"/>
            <end position="248"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU363044"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF05970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF21530"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="OBZ90108.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="363" mass="41294" checksum="1A6BA3BFD61577F5" modified="2016-11-30" version="1">MGFEETDVFHKHSSFYFLSFAKLGSGDHTVTESVERILMSDVAERLWLRARVLIIDEISMIDGSLLDKVEKIARNVRQKQARFGGIQVIMSGDFFQLPPVNRETDAKLAFEAKCWNTVVDKCFILKHCFRQKDSKLVEILNQIRVGYVSEEAEEIFKSLSRTPKANHGIIPTELYPLAHEVCRANRNRLSAINSDAFIFKAVDKGNKGYLDTIRAPLTLELKVGAQVMLIKNLSPVLVNGSLGVVTKFTEEKDSRTYPVVKFTNGIERVMYPELWSISVNGSKVLAYRQQVPLILAWALSIHKSQGQTIEYVKVDLANIFERGHAYVALSRSVTMDNLQILNFDKEKIRVNEKAAEFYKRIES</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NMM7</accession>
    <name>A0A1C7NMM7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Kinesin-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">KIF20A</name>
        <name evidence="9" type="ORF">A0J61_01616</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="5 6">Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000053">
        <property type="protein sequence ID" value="OBZ90335.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="FunCoup" id="A0A1C7NMM7">
        <property type="interactions" value="177"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NMM7"/>
    <dbReference type="InParanoid" id="A0A1C7NMM7"/>
    <dbReference type="OrthoDB" id="123929at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005871">
        <property type="term" value="C:kinesin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008017">
        <property type="term" value="F:microtubule binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003777">
        <property type="term" value="F:microtubule motor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007018">
        <property type="term" value="P:microtubule-based movement"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.850.10">
        <property type="entry name" value="Kinesin motor domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027640">
        <property type="entry name" value="Kinesin-like_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019821">
        <property type="entry name" value="Kinesin_motor_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001752">
        <property type="entry name" value="Kinesin_motor_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036961">
        <property type="entry name" value="Kinesin_motor_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24115:SF1008">
        <property type="entry name" value="KINESIN-LIKE PROTEIN SUBITO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24115">
        <property type="entry name" value="KINESIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00225">
        <property type="entry name" value="Kinesin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00380">
        <property type="entry name" value="KINESINHEAVY"/>
    </dbReference>
    <dbReference type="SMART" id="SM00129">
        <property type="entry name" value="KISc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00411">
        <property type="entry name" value="KINESIN_MOTOR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50067">
        <property type="entry name" value="KINESIN_MOTOR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 6" id="KW-0493">Microtubule</keyword>
    <keyword evidence="4 5 6" id="KW-0505">Motor protein</keyword>
    <keyword evidence="2 5 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Kinesin motor" evidence="8">
        <location>
            <begin position="55"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="629"/>
            <end position="654"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="737"/>
            <end position="756"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="806"/>
            <end position="827"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="9"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="27"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="645"/>
            <end position="654"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="737"/>
            <end position="746"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="144"/>
            <end position="151"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00283"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000394"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50067"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OBZ90335.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="856" mass="99309" checksum="6AA7CA4C0FD9D346" modified="2016-11-30" version="1">MNRHELSLKKHTTNRQKKPLKQLNDTQRYKSYDPEKEPLKVSDHPIDRWFSTNLSTKAYLRIRPKSESHQGQTETPYIDVLDNFEVVMTPPENTYRTRHKTPERYRFTRVFREEIDQQTFFNETCLELVKDTLHGKNALIFAYGVTNSGKTFTMLGKEGSQAGLLPRTMNTIFSSIQHYQGDIKVKPIMHNSLQPYDDDMEENRHLYIRLQEEVDTEDSDMPDQEVQQEVEEEIEVPKIDIDPGFQYAVWISFVEIYNEQLFDLFLPPQTKSKQQKRQPLPLKYDQHTGHKYIGDTHLVRVYTAKQAETMIKLGQKNRQVFSTLMNQSSSRSHSVFTVYLVRYSAHAPEYATLSKLSLVDLAGSERYRNTNSTGQRLKEAGNINKSLMVLGQCMEVLRMNQVKMEMGKAPSLVPFRHSKLTELFKSSFEGDGKAAIIVNVNPVDTGFDENNHVMKFAAVAKDVMTWSQPKLQHALDLPKHTLASSLPIASDDEEEGDDEALTDHMIHQLEELWDKWLDAESRATRAEHDIRMQVTKEMEVEMKRMEDLYLATLKKETDMINDQLKKAIVISEQENNQIESTALLEFQEKQYSMAKELDHLRIKLRKQEVMQTQMIQLEQHKAQGLLLESSSSNLPGSEDEDEANSTDQAGNSESYQTFLSLRKQLRKSIFKKEELCEDADHIMKQVEQFKDVTFQLAKETKMGKLLKLIAQEEFEKDPYQIRNRAIRLFKRYAQLPSNTPSLSPSPITSPTPPLIEPVSRKDTIDLDNVLAENARLKQRIKVLCHGQKRLKGAFERLQTILPSMVEDDDTKENEDTPSXPFLTAEDNQMMEEDYESDITELFKTKGKKRRRKLRVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NNE2</accession>
    <name>A0A1C7NNE2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Alpha/beta hydrolase fold-3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_01321</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000040">
        <property type="protein sequence ID" value="OBZ90625.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NNE2"/>
    <dbReference type="FunCoup" id="A0A1C7NNE2">
        <property type="interactions" value="94"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NNE2"/>
    <dbReference type="InParanoid" id="A0A1C7NNE2"/>
    <dbReference type="OrthoDB" id="408631at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013094">
        <property type="entry name" value="AB_hydrolase_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050300">
        <property type="entry name" value="GDXG_lipolytic_enzyme"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48081">
        <property type="entry name" value="AB HYDROLASE SUPERFAMILY PROTEIN C4A8.06C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48081:SF8">
        <property type="entry name" value="ALPHA_BETA HYDROLASE FOLD-3 DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07859">
        <property type="entry name" value="Abhydrolase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Alpha/beta hydrolase fold-3" evidence="2">
        <location>
            <begin position="92"/>
            <end position="300"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07859"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ90625.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="327" mass="36785" checksum="5176912395F5D18A" modified="2016-11-30" version="1">MSSSLKTPFVYPVYQEMCLYSKKHIYPQFEKNATATPEQQYEFVKKLRADSSEPFVKTKLKETLKSTYIMNEVNTTIFRPPGTEGQLLDVIILLHGGGWIVDDLNTYSKFATDICITSQSAVVFVQYTLSPEVRFPVALEECFSVLYWISENGHSVCLNQHNIVVLGDSAGVNMATVLTMMTKDRGMDNVIKAQVLLYPVTSPKFGIYESHHLFSDAAYGLGKLHNDILYTHYFPNSINTRYASPLLATDEQLKGLPPAFVLTCEADILRDEGEDYASRLMAVGVDTVAIRVKGVIHGYLVDDYPDNSTYIMSLKSICDFIKSIQFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NNG5</accession>
    <name>A0A1C7NNG5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Vacuolar amino acid transporter 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">avt3_1</name>
        <name evidence="8" type="ORF">A0J61_01256</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the amino acid/polyamine transporter 2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000038">
        <property type="protein sequence ID" value="OBZ90683.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NNG5"/>
    <dbReference type="STRING" id="101091.A0A1C7NNG5"/>
    <dbReference type="InParanoid" id="A0A1C7NNG5"/>
    <dbReference type="OrthoDB" id="1684102at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005774">
        <property type="term" value="C:vacuolar membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015179">
        <property type="term" value="F:L-amino acid transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1740.10">
        <property type="entry name" value="Amino acid/polyamine transporter I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013057">
        <property type="entry name" value="AA_transpt_TM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22950">
        <property type="entry name" value="AMINO ACID TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22950:SF666">
        <property type="entry name" value="VACUOLAR AMINO ACID TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01490">
        <property type="entry name" value="Aa_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="47"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="73"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="115"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="161"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="187"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="225"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="258"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="301"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="346"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="371"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="403"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="domain" description="Amino acid transporter transmembrane" evidence="7">
        <location>
            <begin position="41"/>
            <end position="423"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008066"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OBZ90683.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="445" mass="48541" checksum="7B7442D33C944D53" modified="2016-11-30" version="1">MNQSEKELAGPQTAIHEKYHQEEHYESSLAEEQIEHVPEGTASPGKALFMLLKAFIGTGVIFLPGSFLSGGLVLSIVLMIVLAIICCIAFQILVKAQQSIGGSYGDVAQHLYGPYLKHLIQFFLCISQIGFVCSYLIFISENIGIVVDTINNCNSPFAPKYYIWIILAAIIPLCWVRKIAKLSPTAIIGDVFIAFGLVCVLYFSSAQIHDHGIGKNLIMVNQSSFGLMIGTAIFSYEGIGMVLPIVNGMKDPKKFPLVLNLGMLICAVVFTLIGTIGYIAYGDVTQASVVANLPRVPLSTTVQLLYAIAMIFSCPFMLYPPLTIIEEYVFGKRSGTKSPKIKWGKNFVRSLIPLGCAAISFGVGAQNLSKFVSLVGSVACMPLCFIFPGLFHFKITTSKMAKIWDVILILFGVLCMAYTLYVNIDSWIHPVESTGVVIDLATCQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NNK7</accession>
    <name>A0A1C7NNK7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">TBC1 domain family member 15</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">TBC1D15</name>
        <name evidence="2" type="ORF">A0J61_01901</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000066">
        <property type="protein sequence ID" value="OBZ90046.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NNK7"/>
    <dbReference type="STRING" id="101091.A0A1C7NNK7"/>
    <dbReference type="InParanoid" id="A0A1C7NNK7"/>
    <dbReference type="OrthoDB" id="27140at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.270">
        <property type="entry name" value="putative rabgap domain of human tbc1 domain family member 14 like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.750">
        <property type="entry name" value="Ypt/Rab-GAP domain of gyp1p, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.80">
        <property type="entry name" value="Ypt/Rab-GAP domain of gyp1p, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000195">
        <property type="entry name" value="Rab-GAP-TBC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035969">
        <property type="entry name" value="Rab-GAP_TBC_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22957:SF268">
        <property type="entry name" value="ANKYRIN REPEAT-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22957">
        <property type="entry name" value="TBC1 DOMAIN FAMILY MEMBER GTPASE-ACTIVATING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00566">
        <property type="entry name" value="RabGAP-TBC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00164">
        <property type="entry name" value="TBC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47923">
        <property type="entry name" value="Ypt/Rab-GAP domain of gyp1p"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50086">
        <property type="entry name" value="TBC_RABGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rab-GAP TBC" evidence="1">
        <location>
            <begin position="36"/>
            <end position="243"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ90046.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="314" mass="36981" checksum="8B84BDAE203F7915" modified="2016-11-30" version="1">MQTSEEEASYLSDFEDILQSEVYVDLERLRILARHGIPDQLRGEVWKYLLGIQQADRCKLNRNTIDIQSNLHLLAKELSSSKARREEYDQFDKVDNDIAKRIRGEVNRYQRRVPEFDLVGHVQSFVNIILAYLNSNRDVEYNPSMISLCAPFIHVMENECDAYFCFEKLMQAIDEFNQTVSLKEQVAQFMTLFRCSLVELCSYFDEEEVDLNEWSTSWLQNLLSKEMRFENLVRLWVALFLDTYFAIPDPFHFHPFVCLSILQSAKEALEDLEQSEIRTLLLRLPLLNMEMIIADAYNFKHEAMARQVSENDDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NP23</accession>
    <name>A0A1C7NP23_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">THIF-type NAD/FAD binding fold domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_02921</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000118">
        <property type="protein sequence ID" value="OBZ89014.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NP23"/>
    <dbReference type="STRING" id="101091.A0A1C7NP23"/>
    <dbReference type="InParanoid" id="A0A1C7NP23"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005741">
        <property type="term" value="C:mitochondrial outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061503">
        <property type="term" value="F:tRNA threonylcarbamoyladenosine dehydratase"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008641">
        <property type="term" value="F:ubiquitin-like modifier activating enzyme activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061504">
        <property type="term" value="P:cyclic threonylcarbamoyladenosine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045886">
        <property type="entry name" value="ThiF/MoeB/HesA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035985">
        <property type="entry name" value="Ubiquitin-activating_enz"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43267">
        <property type="entry name" value="TRNA THREONYLCARBAMOYLADENOSINE DEHYDRATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43267:SF2">
        <property type="entry name" value="TRNA THREONYLCARBAMOYLADENOSINE DEHYDRATASE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69572">
        <property type="entry name" value="Activating enzymes of the ubiquitin-like proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="14"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="102"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ89014.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="102" mass="11137" checksum="C2AC9FD54B735F4E" modified="2016-11-30" version="1" fragment="single">MNQFFERNQQGTKIALTAIAASVLTASTLLGYQKLTRSRLRERTKSIDTPIALAVTDPEEPKAMDESLILELLARNIAFFGPDHVAAIRRSRVIVLGTGAIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NP68</accession>
    <name>A0A1C7NP68_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">A0J61_01188</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000034">
        <property type="protein sequence ID" value="OBZ90770.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NP68"/>
    <dbReference type="STRING" id="101091.A0A1C7NP68"/>
    <dbReference type="InParanoid" id="A0A1C7NP68"/>
    <dbReference type="OrthoDB" id="194358at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24198">
        <property type="entry name" value="ANKYRIN REPEAT AND PROTEIN KINASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24198:SF194">
        <property type="entry name" value="INVERSIN-A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="40"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="74"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="393"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="420"/>
            <end position="439"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OBZ90770.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="439" mass="49202" checksum="3464ABFB399E9B56" modified="2016-11-30" version="1">MMKESLKEVILSLHWACITGNVGLVKFALDQGVPVDCTVNGFVPLQLSCISDNNIAVTQYLIDRGADVNIQNATGSTALHVACANGCIKTVDLLIRNHALIDIKDKYGSTPLDIAQAKNEVEIVKRLTKKDTRKSVALPILAHRRTTSDKPVRARRPSMPSIFEKQGHPENFNSISSSSSSSPLPVFISMTPEPISRRSFTLAHRPLSEELQPIPIKHAPDQPIRHHKRGRSAYSTEEFSWGPISDSSSSLYRSILSDGSSSVVTLDHHPDWYGYGIVHPYAEDSYLQSLERRAFHSDPDESSVETEEDVLTPTDHVCASAEELRRESLEKNACSLSDDHISPKSKKPIRELAPYQLKKALPLDPMTTAETKKGWFSSFHAYSHDHPLNLDIQSDLDSLPHSKRKNHSRHVSDEKEKPIYQTQQRSGFFSRWTPSWSKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NP73</accession>
    <name>A0A1C7NP73_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_01018</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000028">
        <property type="protein sequence ID" value="OBZ90931.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NP73"/>
    <dbReference type="STRING" id="101091.A0A1C7NP73"/>
    <dbReference type="InParanoid" id="A0A1C7NP73"/>
    <dbReference type="OrthoDB" id="2269275at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ90931.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="336" mass="38635" checksum="B66D2D8DAC210470" modified="2016-11-30" version="1">MYLQATLFAYRTIKQESTKYSPFDVILYNPKYASSKFELTIRTFQQILYLNRIREQAIKNIEISQKNQIETIEKTLLETTRTLKPPFKLGDRVLLYKNYRSISWSSKIETTLKGPYIIQHLLKKCTYSIKSTDTDDTLLKCVHDFGDEVVYDKRVTCSRIDKRPVVGVEESVVVPSDPSPMQGITFSGQSENLFANADKEPVTAAIFTTEVFRPTSLEPMVSKARPLCALPKKGSKTEKMHAKFAKWLLDYEDVARKRDEMIAKAASFHNDLVLKIVKYCQHLKEEPVSQRSFGTYQTRCADVLKSLLRNHSLTYPMVMKAVCRADPWSRCGPFNP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NPN2</accession>
    <name>A0A1C7NPN2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Protein BTG1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">BTG1</name>
        <name evidence="4" type="ORF">A0J61_01083</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the BTG family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000031">
        <property type="protein sequence ID" value="OBZ90859.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NPN2"/>
    <dbReference type="STRING" id="101091.A0A1C7NPN2"/>
    <dbReference type="InParanoid" id="A0A1C7NPN2"/>
    <dbReference type="OrthoDB" id="19928at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.640.90">
        <property type="entry name" value="Anti-proliferative protein, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002087">
        <property type="entry name" value="Anti_prolifrtn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033332">
        <property type="entry name" value="BTG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036054">
        <property type="entry name" value="BTG-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22978">
        <property type="entry name" value="B-CELL TRANSLOCATION GENE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22978:SF22">
        <property type="entry name" value="BTG FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07742">
        <property type="entry name" value="BTG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00310">
        <property type="entry name" value="ANTIPRLFBTG1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00099">
        <property type="entry name" value="btg1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160696">
        <property type="entry name" value="BTG domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Anti-proliferative protein" evidence="3">
        <location>
            <begin position="1"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="117"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="128"/>
            <end position="137"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00099"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OBZ90859.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="176" mass="20294" checksum="57CD42473974540D" modified="2016-11-30" version="1">MHIEINQAAEFLGRFLQPKIDAESIQNFKHSLMELLAQRFTNHWDAQQPYRGNGYRAISNFHGQLDPIIIKACDKATCSIHLVHSNLPRDFVLWIDPYNVSYRVGDHGNIMTLYEDDPRKPHPPKASFLQSTPSTPIRMSPPSSPETRVKKMNKAHQPSPLSYYYEQSDENMVMVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NPW9</accession>
    <name>A0A1C7NPW9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_00796</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000020">
        <property type="protein sequence ID" value="OBZ91157.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NPW9"/>
    <dbReference type="InParanoid" id="A0A1C7NPW9"/>
    <dbReference type="OrthoDB" id="2252251at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="46"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="73"/>
            <end position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ91157.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="82" mass="9084" checksum="B204B8EAEF4B5CDD" modified="2016-11-30" version="1">MSSSPPDHPGNNRWQTFEEWHKIKTRSFVQVAKSDSETMKEAFERFGLKEDEEGNGWGDASEAQDAGWGTPKGANSNPAGGW</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NQ01</accession>
    <name>A0A1C7NQ01_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Yeast cell wall synthesis Kre9/Knh1-like N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">A0J61_00768</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000019">
        <property type="protein sequence ID" value="OBZ91191.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NQ01"/>
    <dbReference type="InParanoid" id="A0A1C7NQ01"/>
    <dbReference type="OrthoDB" id="5589325at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018466">
        <property type="entry name" value="Kre9/Knh1-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052982">
        <property type="entry name" value="SRP1/TIP1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40633:SF1">
        <property type="entry name" value="GPI ANCHORED SERINE-THREONINE RICH PROTEIN (AFU_ORTHOLOGUE AFUA_1G03630)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40633">
        <property type="entry name" value="MATRIX PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_8G05410)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10342">
        <property type="entry name" value="Kre9_KNH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008889818" description="Yeast cell wall synthesis Kre9/Knh1-like N-terminal domain-containing protein" evidence="2">
        <location>
            <begin position="19"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="domain" description="Yeast cell wall synthesis Kre9/Knh1-like N-terminal" evidence="3">
        <location>
            <begin position="28"/>
            <end position="121"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF10342"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OBZ91191.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="192" mass="18323" checksum="6A12C9C279BD9AAA" modified="2016-11-30" version="1">MKFSVAALLSLAASAVYAQNAGVAVNLPSIGQVLTAGTSFTITWTVDANATASSTINSIALMKGNSANLETVVPNILSAAIPVTPSSYNWNIPANIETNPSYALVLAGSNGGTTYSTYFTILNNGVAAASSGAASSAAATSGAAASGAASQSAKSSSSASASPSSTSTSGASGLKAGLVGAGAIAGAVALLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NQB8</accession>
    <name>A0A1C7NQB8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_00638</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000015">
        <property type="protein sequence ID" value="OBZ91311.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NQB8"/>
    <dbReference type="InParanoid" id="A0A1C7NQB8"/>
    <dbReference type="OrthoDB" id="2269335at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="95"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="190"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ91311.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="190" mass="21931" checksum="4B803841338E1040" modified="2016-11-30" version="1" fragment="single">FGFVKSSNPVFISYHQIKDCLKDVLSEAWNNVNIIQKLSQKFYFNKKETTKSALKQQLSDFWDQNTTANSRPISILIKKNLSEQEKLHFEAGFRLQAAKEVNQEQEEEEVASQEEAVEQEEAVVQKKMTQLLALPREEKVKKLGLEGKVETIVNFNDKQTLDLSKARTIPSRCKDIIDSILIQDYSYTLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NQF8</accession>
    <name>A0A1C7NQF8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Splicing factor 3B subunit 4</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">SF3B4</name>
        <name evidence="12" type="ORF">A0J61_00622</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SF3B4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000014">
        <property type="protein sequence ID" value="OBZ91347.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NQF8"/>
    <dbReference type="FunCoup" id="A0A1C7NQF8">
        <property type="interactions" value="654"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NQF8"/>
    <dbReference type="InParanoid" id="A0A1C7NQF8"/>
    <dbReference type="OrthoDB" id="10259687at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071011">
        <property type="term" value="C:precatalytic spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005686">
        <property type="term" value="C:U2 snRNP"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048026">
        <property type="term" value="P:positive regulation of mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008380">
        <property type="term" value="P:RNA splicing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd12334">
        <property type="entry name" value="RRM1_SF3B4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd12335">
        <property type="entry name" value="RRM2_SF3B4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.330:FF:000059">
        <property type="entry name" value="splicing factor 3B subunit 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.330:FF:000121">
        <property type="entry name" value="Splicing factor 3b subunit 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034158">
        <property type="entry name" value="SF3B4_RRM1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034159">
        <property type="entry name" value="SF3B4_RRM2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052084">
        <property type="entry name" value="SF3B4_spliceosome_assoc"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48030">
        <property type="entry name" value="SPLICING FACTOR 3B SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48030:SF3">
        <property type="entry name" value="SPLICING FACTOR 3B SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="7" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="6 10" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4" id="KW-0747">Spliceosome</keyword>
    <feature type="domain" description="RRM" evidence="11">
        <location>
            <begin position="11"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="11">
        <location>
            <begin position="98"/>
            <end position="177"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00070533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="OBZ91347.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="269" mass="29379" checksum="58119BCB18FE0D28" modified="2016-11-30" version="1">MAQQIERNQEATIYIGNLDERCTESLVWELMLQAGPVVNVHLPKDRVTQTHQSYGFVEFLTEEDADYAIKIMNQVRLYGKPVRVNKATSDKKNLDVGATLFIGNLDPEVDEKMLYDTFSAFGLIVNTPKISRDPETGLSKGFGFVSFDNFESSDAAIDSMEGQYLMNKQITVSYAFKKDGKGERHGSAAERLLAAEGRKNVQMPNRLYAGGPAMAPAANAGTNTVSSYPGGMNGFRPPPPPAMGAAAGYPMGYSQAQYATPPPPPPVWQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NQJ6</accession>
    <name>A0A1C7NQJ6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">ATP synthase subunit alpha, mitochondrial</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">ATP1_1</name>
        <name evidence="14" type="ORF">A0J61_02418</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ATPase alpha/beta chains family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000090">
        <property type="protein sequence ID" value="OBZ89544.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NQJ6"/>
    <dbReference type="STRING" id="101091.A0A1C7NQJ6"/>
    <dbReference type="InParanoid" id="A0A1C7NQJ6"/>
    <dbReference type="OrthoDB" id="9805536at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045259">
        <property type="term" value="C:proton-transporting ATP synthase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043531">
        <property type="term" value="F:ADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046933">
        <property type="term" value="F:proton-transporting ATP synthase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd18116">
        <property type="entry name" value="ATP-synt_F1_alpha_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.30.20:FF:000001">
        <property type="entry name" value="ATP synthase subunit alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:004039">
        <property type="entry name" value="ATP synthase subunit alpha, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023366">
        <property type="entry name" value="ATP_synth_asu-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005294">
        <property type="entry name" value="ATP_synth_F1_asu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004100">
        <property type="entry name" value="ATPase_F1/V1/A1_a/bsu_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036121">
        <property type="entry name" value="ATPase_F1/V1/A1_a/bsu_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000194">
        <property type="entry name" value="ATPase_F1/V1/A1_a/bsu_nucl-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48082">
        <property type="entry name" value="ATP SYNTHASE SUBUNIT ALPHA, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48082:SF2">
        <property type="entry name" value="ATP SYNTHASE SUBUNIT ALPHA, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00006">
        <property type="entry name" value="ATP-synt_ab"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02874">
        <property type="entry name" value="ATP-synt_ab_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50615">
        <property type="entry name" value="N-terminal domain of alpha and beta subunits of F1 ATP synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0066">ATP synthesis</keyword>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10" id="KW-0139">CF(1)</keyword>
    <keyword evidence="6" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="8" id="KW-0406">Ion transport</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ATPase F1/V1/A1 complex alpha/beta subunit N-terminal" evidence="13">
        <location>
            <begin position="64"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="domain" description="ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding" evidence="12">
        <location>
            <begin position="187"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="14">
        <location>
            <position position="281"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00016087"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023196"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023310"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF00006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF02874"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="OBZ89544.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="281" mass="29770" checksum="A37486C286A74264" modified="2016-11-30" version="1" fragment="single">MLRNATRLARPTLAAFARSTPARLNLGAAAVGLRNYASAKPSTSEVSSILEQRILGANSEVDLQETGRVLSIGDGIARVYGLKNCQAEEMVEFSSGLKGMALNLEADNVGIVVFGNDRLIKEGDTVKRTGAIVDVPIGPGLLGRVVDALGNPIDGKGPLDAAGRSRVQVKAPGILPRHSVNEPMQTGIKSVDSMVPIGRGQRELIIGDRQTGKTAVALDTILNQKNWNNGSDEAKKLYCIYVAVGQKRSTVAQLVRTLEENDAMKYTIVVAATASEAAPLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NQK6</accession>
    <name>A0A1C7NQK6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Trafficking protein particle complex subunit 9</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">A0J61_00651</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Golgi apparatus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000015">
        <property type="protein sequence ID" value="OBZ91318.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NQK6"/>
    <dbReference type="FunCoup" id="A0A1C7NQK6">
        <property type="interactions" value="73"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NQK6"/>
    <dbReference type="InParanoid" id="A0A1C7NQK6"/>
    <dbReference type="OrthoDB" id="27962at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005802">
        <property type="term" value="C:trans-Golgi network"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058565">
        <property type="entry name" value="Ig_TRAPPC9_Trs120_1st"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058567">
        <property type="entry name" value="Ig_TRAPPC9_Trs120_3rd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058568">
        <property type="entry name" value="Ig_TRAPPC9_Trs120_4th"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058564">
        <property type="entry name" value="TPR_TRAPPC9_Trs120"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013935">
        <property type="entry name" value="Trs120_TRAPPC9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058563">
        <property type="entry name" value="Trs120_TRAPPC9_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21512">
        <property type="entry name" value="TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21512:SF5">
        <property type="entry name" value="TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26254">
        <property type="entry name" value="Ig_TRAPPC9-Trs120_1st"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26280">
        <property type="entry name" value="Ig_TRAPPC9-Trs120_2nd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26282">
        <property type="entry name" value="Ig_TRAPPC9-Trs120_3rd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26283">
        <property type="entry name" value="Ig_TRAPPC9-Trs120_4th"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26251">
        <property type="entry name" value="TPR_TRAPPC9-Trs120"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08626">
        <property type="entry name" value="TRAPPC9-Trs120"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Trs120/TRAPPC9 N-terminal" evidence="4">
        <location>
            <begin position="6"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="domain" description="Trs120/TRAPPC9 TPR region" evidence="5">
        <location>
            <begin position="345"/>
            <end position="594"/>
        </location>
    </feature>
    <feature type="domain" description="Trs120/TRAPPC9 first Ig-like" evidence="6">
        <location>
            <begin position="610"/>
            <end position="780"/>
        </location>
    </feature>
    <feature type="domain" description="Trs120/TRAPPC9 third Ig-like" evidence="7">
        <location>
            <begin position="951"/>
            <end position="1131"/>
        </location>
    </feature>
    <feature type="domain" description="Trs120/TRAPPC9 fourth Ig-like" evidence="8">
        <location>
            <begin position="1136"/>
            <end position="1260"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="203"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="214"/>
            <end position="224"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF08626"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF26251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF26254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF26282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF26283"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OBZ91318.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1266" mass="144158" checksum="AAE963C4ACAB0424" modified="2016-11-30" version="1">MNINTSLTSNCKVRVLLVPVSPIKRTTFSKYVELVKTFEVVRLGDVTPDLKKGASAMFTSQAFQEGQMHFEFLDHYSREHQELEEFQPYRRIFGIIGIMDCQEWEKKGLKEGHHQFVRSLDHYPSSVVTRCFAFEPSETQEDDTKGLIMMPNVGNMSFYMSTMMCDFASEILELFSVLATSIQSTGVIESPLALNTPIKNRAQQRLSQPPLATPSRTSYISSKRASLPMPSTRVSEEENRSRKRTPGRIQKLLGDFYLLAGRLPDAIHYYDQAIESNKTMSDFLWLTSAMEGWLCATFLLDHLQIDIGHIVSRMVIPSQPSYTSPEQVELPPTPTTPKAPRSMLDLLIEQYSLIHTYYSRVTLTASFPAPDIVFAESCLRIARVLTTAYLNGGWNDTTVQCIMQGELSQGKIKGVQKQSGIKQCQIGDWVTKIWKIRMDQLSLLDQISLLNGMSLIYSCIGYHRKAAWTRHQSVKSMLPLIVQHRRSNLSKDKPSDQGVLDMLKQVCEIYGVGEKSIRLADQGPSKSHDLFGWPALQIEVLKQCISISEALIDNNLRLYYTNVLLRSLYQYIPKAEQIKLATTIQSIIVHSNRDKQAMSSSMNYWGVNLVSSIELKKLISRKAVYAHSAKQEPVKEDKEVSDDPFIYNPFAKKQVVHQKAVLVKNELSEFQVSLLNPFGFDLELQNIVLSTSGVEFEAVPTGTTIPANATSQIQLMGTPKEAGVLIIRGCLIRIIGFAEQEFTVDSKSTKPIDRQTKLKSSGLKTLDLQKDKEQVNASEEEQFVTMDVIDDQPLLKIKRSSLLHGAIMLFEGEVAHMTMDLENIGTIPIDFIALSFVDSTTSNPILINPELLPEEKYEIELYTKDTRVFSCADLIDRRYNQLNGRKIWLPPGEITTIKVNIYGKKDCHHGTIQVDYGFLERSSETVLSLFYTRQLYYNVLVTVYQNLECSSWDVAHLRHSLPPSKDSLVPTGNHPLSSIEDLLMMTRNVEMENQDFCLVTLDVQNTWSTLFDVEFMIYNDDPSKDNGQVIFHLPVQPGSTARAILPIKRLFLPLDVCQQTIPSLDVNRQFVVSQGPKLSKEQQQARLQIFWYREELLSRIKASWRCRVSQRTGDLNLRPSLRFSQTQLAIFKKEDIEFSVDMKGQSVTKLSGRRFICECNDPTIMTITVKNRFPYPIKVILRLQPVQSYNDGAKEYDLSEKLLVEGIEQVVLPEIPAIHGQVAHSFPLYFLSRGQFELLYHAEDVYKRKIYYDHEWVIVDTIDSTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NQW7</accession>
    <name>A0A1C7NQW7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">N-acetyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_00633</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000015">
        <property type="protein sequence ID" value="OBZ91309.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NQW7"/>
    <dbReference type="STRING" id="101091.A0A1C7NQW7"/>
    <dbReference type="InParanoid" id="A0A1C7NQW7"/>
    <dbReference type="OrthoDB" id="74247at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd04301">
        <property type="entry name" value="NAT_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045057">
        <property type="entry name" value="Gcn5-rel_NAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031165">
        <property type="entry name" value="GNAT_YJDJ"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31435:SF10">
        <property type="entry name" value="BSR4717 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31435">
        <property type="entry name" value="PROTEIN NATD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14542">
        <property type="entry name" value="Acetyltransf_CG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51729">
        <property type="entry name" value="GNAT_YJDJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="61"/>
            <end position="150"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ91309.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="166" mass="19311" checksum="DDAFE584A4650BCE" modified="2016-11-30" version="1">MSSSEWNEQKVGENVHLGKKQHIVYTQLFPFLSFGQRLLKSSHHLVLNRESQIQMKQSKVFHDEKQCMFLLRLDQKGTIAALCYLPTRVKKVIEVYHIEIPIKFRHRGVGDKLVKEFLDWAKESGTLVIPACNFVKRHLELFDYGTTIVSNEQEAVKYFVSTMKSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NQZ5</accession>
    <name>A0A1C7NQZ5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 3">Vacuolar fusion protein MON1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">MON1A</name>
        <name evidence="8" type="ORF">A0J61_00418</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Required for multiple vacuole delivery pathways including the cytoplasm to vacuole transport (Cvt), autophagy, pexophagy and endocytosis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Endosome</location>
            <location evidence="3">Multivesicular body membrane</location>
            <topology evidence="3">Peripheral membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1 3">Prevacuolar compartment membrane</location>
            <topology evidence="1 3">Peripheral membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="3">Vacuole membrane</location>
            <topology evidence="3">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the MON1/SAND family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000009">
        <property type="protein sequence ID" value="OBZ91522.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NQZ5"/>
    <dbReference type="FunCoup" id="A0A1C7NQZ5">
        <property type="interactions" value="279"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NQZ5"/>
    <dbReference type="InParanoid" id="A0A1C7NQZ5"/>
    <dbReference type="OrthoDB" id="272411at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000329">
        <property type="term" value="C:fungal-type vacuole membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035658">
        <property type="term" value="C:Mon1-Ccz1 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032585">
        <property type="term" value="C:multivesicular body membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006914">
        <property type="term" value="P:autophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006623">
        <property type="term" value="P:protein targeting to vacuole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016192">
        <property type="term" value="P:vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043972">
        <property type="entry name" value="FUZ/MON1/HPS1_longin_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043971">
        <property type="entry name" value="FUZ/MON1/HPS1_longin_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043970">
        <property type="entry name" value="FUZ/MON1/HPS1_longin_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004353">
        <property type="entry name" value="Mon1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13027">
        <property type="entry name" value="SAND PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13027:SF7">
        <property type="entry name" value="VACUOLAR FUSION PROTEIN MON1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19036">
        <property type="entry name" value="Fuz_longin_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19037">
        <property type="entry name" value="Fuz_longin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19038">
        <property type="entry name" value="Fuz_longin_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01546">
        <property type="entry name" value="YEAST73DUF"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0072">Autophagy</keyword>
    <keyword evidence="3" id="KW-0967">Endosome</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0653">Protein transport</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <keyword evidence="3" id="KW-0926">Vacuole</keyword>
    <feature type="domain" description="FUZ/MON1/HPS1 first Longin" evidence="5">
        <location>
            <begin position="83"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="domain" description="FUZ/MON1/HPS1 second Longin" evidence="6">
        <location>
            <begin position="243"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="domain" description="FUZ/MON1/HPS1 third Longin" evidence="7">
        <location>
            <begin position="369"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="56"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="17"/>
            <end position="40"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004380"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00018132"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU367048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF19036"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF19037"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF19038"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OBZ91522.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="445" mass="51028" checksum="9358601564CF0431" modified="2016-11-30" version="1">MTSLKEPVFAQREDDATTSSSASDDNNSLGRRTSCSSADSTDSDPVKTFNKLRRQGSRSSVLLQPSARREKDTDQNTWIQHKKHFFILSSAGKPVWTRYGDESRLSSLMGVIQAIISFFQDGDDTIKSINAGHHKCVFLLKEPLYYVSVSKTGESDSQIRDQLLYLHNQILSVLTSVQLTRIFEQRVNFDLRRLLGGTEVFLDSLSTLFHNDHSFMLSSLQCLRLNKTMRDQAGDILLNGKVKQLLYAMVVADGKLVTLLRPRKHSLHPSDLHLLFNMLTGSTTFHTAESWTPLCLPKFNSKGFLHAYICYIEKGISIVVISTDKNNFFEISEWKSSMVESLQKTGVLKHIKEANEKSYSVEDIQVPSLIHFMYKSKVHVQFTTPGLSNIYTNEIDKKRLFRMYQHVHDRMHRRSRPLKLYYINSEKEVVLGWVTVFGDNHIFLY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NRL0</accession>
    <name>A0A1C7NRL0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">F-box protein pof7</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">pof7</name>
        <name evidence="4" type="ORF">A0J61_00346</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000007">
        <property type="protein sequence ID" value="OBZ91610.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NRL0"/>
    <dbReference type="FunCoup" id="A0A1C7NRL0">
        <property type="interactions" value="79"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NRL0"/>
    <dbReference type="InParanoid" id="A0A1C7NRL0"/>
    <dbReference type="OrthoDB" id="2117972at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019005">
        <property type="term" value="C:SCF ubiquitin ligase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031146">
        <property type="term" value="P:SCF-dependent proteasomal ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd22089">
        <property type="entry name" value="F-box_FBXO9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045464">
        <property type="entry name" value="Hrt3/FBXO9_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12874:SF9">
        <property type="entry name" value="F-BOX ONLY PROTEIN 48"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12874">
        <property type="entry name" value="F-BOX ONLY PROTEIN 48-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12937">
        <property type="entry name" value="F-box-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19270">
        <property type="entry name" value="FBO_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="F-box" evidence="3">
        <location>
            <begin position="206"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="7"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="50"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OBZ91610.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="465" mass="54336" checksum="9D47D76BD1FEC687" modified="2016-11-30" version="1">MNSLSDNNKKGNPEQQEKDLEEFRNAWKREVQEKHSYDVHKQTGDSSKSATEKEDKHKPGEEAIDNLIEQAESLTTTDPSEPVTAMDHYVIAVDNERQGKLGKGNFSMACDTKRASAALDSYRRAFKLDPDIDFVYKKHFQKDILPKIQATKDQPQQPSEGFKHIVPLGKEYVAPSATRRDPLADLIEQFLSEDDISYIPRLDYKPVAIAKLPSEIILNILKILVLHSVSTIPYFARVCKKFFLYTRDPSIWQYACIRVFREPSMTLADSRQRCMEYVQKFDGHWMRMFIDRPRIRYDGLYISTCHYIRPGTSDTAWNKPIHLVTYYRYLRFFPDGRILKHVTTEEPAHVVKQLQLGFNKKQSFHGQFTMDAEDHISIVMKDFTLPRETFRLSLKIKTTHRGKHNKLNWDQYSSTSAGIDRDDHLYDLKLLKPYFFSPVRSYRVHYPDELQEEADLDHSLLLMLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NRN0</accession>
    <name>A0A1C7NRN0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_00242</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000005">
        <property type="protein sequence ID" value="OBZ91678.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NRN0"/>
    <dbReference type="InParanoid" id="A0A1C7NRN0"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008889850" description="Secreted protein" evidence="2">
        <location>
            <begin position="28"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="30"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="58"/>
            <end position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ91678.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="67" mass="7752" checksum="DFE4C75A18E2DC18" modified="2016-11-30" version="1">MFTNKNSESRVAFLIVLICLGLIFTDSNRHPSQFGQESHKRSAFDQKPTCPSKIDLKQQQQQQRSKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NS11</accession>
    <name>A0A1C7NS11_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">J domain-containing protein spf31</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">spf31</name>
        <name evidence="3" type="ORF">A0J61_00014</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000001">
        <property type="protein sequence ID" value="OBZ91887.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NS11"/>
    <dbReference type="FunCoup" id="A0A1C7NS11">
        <property type="interactions" value="719"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NS11"/>
    <dbReference type="InParanoid" id="A0A1C7NS11"/>
    <dbReference type="OrthoDB" id="342454at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46620">
        <property type="entry name" value="J DOMAIN-CONTAINING PROTEIN SPF31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46620:SF1">
        <property type="entry name" value="J DOMAIN-CONTAINING PROTEIN SPF31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="J" evidence="2">
        <location>
            <begin position="33"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="180"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="180"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="225"/>
            <end position="238"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ91887.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="238" mass="27650" checksum="BC5EDA730B070DA2" modified="2016-11-30" version="1">MSALASEEDLDRYFSQTEKQIEIDRVLSCFKLDPFAILELPYNKPDPKAIKMAYRKKSLMIHPDKVKHERAQDAFALLKKAESELTDETRLAFLMTVIEEARVEVLRENGHKVKTQVIVNAPTQNAEDGSLKASLDSKAVLDEKEYPYLQTTEGQTQVKNKMKEILIEMELRRRKQLKKEMEAEGAEKRKAEEIVNERKRKAEDAKQWEASRDNRVNSWRDFQKKGGKKVKKIRKSGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7LLQ0</accession>
    <name>A0A1C7LLQ0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Tigger transposable element-derived protein 6</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">TIGD6_0</name>
        <name evidence="2" type="ORF">A0J61_11976</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01002805">
        <property type="protein sequence ID" value="OBZ62910.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7LLQ0"/>
    <dbReference type="FunCoup" id="A0A1C7LLQ0">
        <property type="interactions" value="216"/>
    </dbReference>
    <dbReference type="InParanoid" id="A0A1C7LLQ0"/>
    <dbReference type="OrthoDB" id="2446582at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050863">
        <property type="entry name" value="CenT-Element_Derived"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004875">
        <property type="entry name" value="DDE_SF_endonuclease_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19303:SF73">
        <property type="entry name" value="PROTEIN PDC2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19303">
        <property type="entry name" value="TRANSPOSON"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03184">
        <property type="entry name" value="DDE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DDE-1" evidence="1">
        <location>
            <begin position="80"/>
            <end position="200"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ62910.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="207" mass="23518" checksum="6A645CA25DE8CCD6" modified="2016-11-30" version="1">MAGFLVFKRIGVKSRLTHGESALVDITTENIQGQLKKIAELLQPYNPQNILNFDKTGLYYNQPPRRTISSQPVGGMKNSKERLTIWFFCNADGSYKGHLIVIGKHKYPTGYKDNPKLHAMTAIGKPHYIEYHCSPNALMKKEIFEGYVKRLDRPFGREKRKVAILLDNASVHKVGYQPENILLGFLPANTTSKLQPLDAGNHLRIYH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MU78</accession>
    <name>A0A1C7MU78_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">phosphoacetylglucosamine mutase</fullName>
            <ecNumber evidence="5">5.4.2.3</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Acetylglucosamine phosphomutase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">N-acetylglucosamine-phosphate mutase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="primary">PGM3</name>
        <name evidence="14" type="ORF">A0J61_11603</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>N-acetyl-alpha-D-glucosamine 1-phosphate = N-acetyl-D-glucosamine 6-phosphate</text>
            <dbReference type="Rhea" id="RHEA:23804"/>
            <dbReference type="ChEBI" id="CHEBI:57513"/>
            <dbReference type="ChEBI" id="CHEBI:57776"/>
            <dbReference type="EC" id="5.4.2.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Nucleotide-sugar biosynthesis; UDP-N-acetyl-alpha-D-glucosamine biosynthesis; N-acetyl-alpha-D-glucosamine 1-phosphate from alpha-D-glucosamine 6-phosphate (route I): step 2/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the phosphohexose mutase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.4.2.3" evidence="5"/>
    <dbReference type="EMBL" id="LUGH01002241">
        <property type="protein sequence ID" value="OBZ80348.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MU78"/>
    <dbReference type="FunCoup" id="A0A1C7MU78">
        <property type="interactions" value="116"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7MU78"/>
    <dbReference type="InParanoid" id="A0A1C7MU78"/>
    <dbReference type="OrthoDB" id="1928at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004610">
        <property type="term" value="F:phosphoacetylglucosamine mutase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006048">
        <property type="term" value="P:UDP-N-acetylglucosamine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.120.10:FF:000013">
        <property type="entry name" value="Phosphoacetylglucosamine mutase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.120.10:FF:000015">
        <property type="entry name" value="Phosphoacetylglucosamine mutase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.120.10:FF:000019">
        <property type="entry name" value="Phosphoacetylglucosamine mutase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.120.10">
        <property type="entry name" value="Alpha-D-Glucose-1,6-Bisphosphate, subunit A, domain 3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005844">
        <property type="entry name" value="A-D-PHexomutase_a/b/a-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016055">
        <property type="entry name" value="A-D-PHexomutase_a/b/a-I/II/III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016066">
        <property type="entry name" value="A-D-PHexomutase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049023">
        <property type="entry name" value="AMG1_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049022">
        <property type="entry name" value="AMG1_III"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45955">
        <property type="entry name" value="PHOSPHOACETYLGLUCOSAMINE MUTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45955:SF1">
        <property type="entry name" value="PHOSPHOACETYLGLUCOSAMINE MUTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21405">
        <property type="entry name" value="AMG1_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21404">
        <property type="entry name" value="AMG1_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02878">
        <property type="entry name" value="PGM_PMM_I"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53738">
        <property type="entry name" value="Phosphoglucomutase, first 3 domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00710">
        <property type="entry name" value="PGM_PMM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0413">Isomerase</keyword>
    <keyword evidence="7" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Alpha-D-phosphohexomutase alpha/beta/alpha" evidence="11">
        <location>
            <begin position="6"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="domain" description="Alpha-D-phosphohexomutase alpha/beta/alpha" evidence="11">
        <location>
            <begin position="56"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="domain" description="Phosphoacetylglucosamine mutase AMG1" evidence="13">
        <location>
            <begin position="137"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="domain" description="Phosphoacetylglucosamine mutase AMG1" evidence="12">
        <location>
            <begin position="249"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="14">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000558"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010231"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012731"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00031926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00032065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF02878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF21404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF21405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="OBZ80348.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="345" mass="37183" checksum="8557B33E3CD49085" modified="2016-11-30" version="1" fragment="single">LNGSTIGVMITASHNPEEDNGVKLVDPRGEMLEQSWEVYATKLANAKEGEALVQVIDEIVAQNKIDIQAPAQVIYAHDTRPSCPQLVQALELGLKASGAQHTNYGLKTTPMLHYLVRCINTAGTNDAYGEPTEEGYYKKLTAAYTTAVKGKPRLSTLVVDCANGVGAPKLREMTKFISEDVLSVQVVNDDITSLGQLNKNCGADFVKTQQRGPHGVTLKAGERYCSFDGDADRIVFYYATEDGTFRLLDGDKIAGLAALFIAELVKEAGIESIKVGVVQTAYANGSSTNYLTKVLNVPVSCVSTGVKHLHHEAEKYDVGVYFEANGHGTVLFSPHALNTIKSAES</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MUQ7</accession>
    <name>A0A1C7MUQ7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Wbp11/ELF5/Saf1 N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_11350</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001936">
        <property type="protein sequence ID" value="OBZ80601.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MUQ7"/>
    <dbReference type="STRING" id="101091.A0A1C7MUQ7"/>
    <dbReference type="InParanoid" id="A0A1C7MUQ7"/>
    <dbReference type="OrthoDB" id="205569at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006396">
        <property type="term" value="P:RNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019007">
        <property type="entry name" value="Wbp11/ELF5/Saf1_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09429">
        <property type="entry name" value="Wbp11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Wbp11/ELF5/Saf1 N-terminal" evidence="2">
        <location>
            <begin position="5"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="108"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="25"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="108"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="134"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="156"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="194"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="204"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="221"/>
            <end position="234"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF09429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ80601.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="310" mass="35137" checksum="A0D5A661562EDC46" modified="2016-11-30" version="1">MAKSKRTMNPADALRKQQRKRELKKNKEDRKRVRESALAKKDLGKIKQDISRLEHLARLGQLDKAGQSRLDGLKMEAAKIEKAKKVCKKKERDHDTQCAQAAFVARMQEQEKKHENEARKLVYDPKRGAFVPAKKKEKDTKTVSHESEDSNSSTSDESDSDSSMEEEEDVPLPQEEETAKKTELTESDDDYDIPLPPGPPPQRPFDSQLMPIQQQQQQSRLPPPPPPGPPPFRGPFPVYQPRMPPPPPPLMTGLVHPPPHRPTRPSEENRPKAIEVAPTISAEPQLRDLQKELLGFVPAAIRRKQIKKGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-06-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MUY8</accession>
    <name>A0A1C7MUY8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_11270</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001845">
        <property type="protein sequence ID" value="OBZ80681.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MUY8"/>
    <dbReference type="InParanoid" id="A0A1C7MUY8"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="28"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ80681.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="236" mass="26305" checksum="281133158D00FA43" modified="2016-11-30" version="1" fragment="single">ASHAVPLVPVVSAAPVVSAASLSSAAALAAANAEQKALEKKVRRLEIRLAQIEALMIDTDSAPGPGRGHGRNPMHVRVVREAFEVAKNTYGLEFNQDFSMKNRLVNLAVYIKIIELSVDVIKTLAGLTQTQTLAPVVMRSLDSRIRNRFEDARRTSRTAALPALDRQEYKDNDAKRKRLSRKKNNRDACFKKAKDNFLLALGQPRSLNKFFHAVDEEDLFNKSSSCDERTYEVVEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MUZ5</accession>
    <name>A0A1C7MUZ5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Retrovirus-related Pol polyprotein from transposon 17.6</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">pol_14</name>
        <name evidence="3" type="ORF">A0J61_11236</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001812">
        <property type="protein sequence ID" value="OBZ80715.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MUZ5"/>
    <dbReference type="STRING" id="101091.A0A1C7MUZ5"/>
    <dbReference type="InParanoid" id="A0A1C7MUZ5"/>
    <dbReference type="OrthoDB" id="2286699at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd09274">
        <property type="entry name" value="RNase_HI_RT_Ty3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01647">
        <property type="entry name" value="RT_LTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.270:FF:000020">
        <property type="entry name" value="Transposon Tf2-6 polyprotein-like Protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.270:FF:000003">
        <property type="entry name" value="Transposon Ty3-G Gag-Pol polyprotein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.10.10">
        <property type="entry name" value="HIV Type 1 Reverse Transcriptase, subunit A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043502">
        <property type="entry name" value="DNA/RNA_pol_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000477">
        <property type="entry name" value="RT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041577">
        <property type="entry name" value="RT_RNaseH_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051320">
        <property type="entry name" value="Viral_Replic_Matur_Polypro"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33064">
        <property type="entry name" value="POL PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33064:SF37">
        <property type="entry name" value="RIBONUCLEASE H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17919">
        <property type="entry name" value="RT_RNaseH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00078">
        <property type="entry name" value="RVT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56672">
        <property type="entry name" value="DNA/RNA polymerases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Reverse transcriptase" evidence="1">
        <location>
            <begin position="163"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="domain" description="Reverse transcriptase/retrotransposon-derived protein RNase H-like" evidence="2">
        <location>
            <begin position="311"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="465"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF17919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ80715.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="465" mass="53672" checksum="2ABED39958C6E08C" modified="2016-11-30" version="1" fragment="single">MLNNENINQEQKDRLLKLINEYADCFGTNYEHLSQTNLVEFHVDTADAKPIYKRPYAYMSHAEKEFLKQDLKGMVDNGILVPTTHVKGNTKSGGWSFPCRYVGKKTGDRRLISMFQDLNKVTVRDPWPLPNLVDVIEDLGKSQWYSQLDLLKGFHQIKVHPESCLPFGVLNGPSCFSRAIYLAMEPFINSSVTVYLDDCTVHSKTFDEHMEHLEAVFKRLLEVNMKLNANKVELFTDKIELLGFHVSPNGISPVSTKVDKMLNFSRPMCQKNVRAFVNLCGFYRRHIPFFSQISSKMNELLKKNKPFIRDNDCQESFEKLKKALVDAATLNFPDPKKPYRLYTDASDIAIGACLAQLDDNDEERPICFMSRKLQPAEFRKYLLDKPFTLFTDNSAVQYMFSKNTPNQRLQRWVMAAQDLTFKCVHLKTKFNPVADAMSRYPTTYEVKGDELNGEDDLEALYEHLM</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-09-13" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MV97</accession>
    <name>A0A1C7MV97_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Cyanovirin-N domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_11190</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001760">
        <property type="protein sequence ID" value="OBZ80762.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MV97"/>
    <dbReference type="InParanoid" id="A0A1C7MV97"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008889324" description="Cyanovirin-N domain-containing protein" evidence="1">
        <location>
            <begin position="21"/>
            <end position="126"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ80762.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="126" mass="14517" checksum="9E9AB5C11066C5AE" modified="2016-11-30" version="1">MMFLTLFILNAMAFLSVVSADDVWSLTYHCFDKEEVVLVHTNEFGAQSIIWNRRNLNGRNELCTSNQVVCMKDVAVHMKSCDEVNFDLKVQYAGKWSTNNNPVFHGVRSGPSQEYKVYEFIPEFLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MVC0</accession>
    <name>A0A1C7MVC0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_11116</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001687">
        <property type="protein sequence ID" value="OBZ80835.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MVC0"/>
    <dbReference type="STRING" id="101091.A0A1C7MVC0"/>
    <dbReference type="InParanoid" id="A0A1C7MVC0"/>
    <dbReference type="OrthoDB" id="2287989at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="51"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="105"/>
            <end position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ80835.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="131" mass="14653" checksum="C658BAD218334D10" modified="2016-11-30" version="1">MSISPSKIIYNLANIETALVIANEWKECFDRISELSASKWIKKRGESAENLIMGETRERHRRSQQTPTRAMRISQKDSKKIGCKGTSSILQYVQNPGVVEIKMSMGHANHAPGSNSDIRTLPPTRGNRNGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MVU6</accession>
    <name>A0A1C7MVU6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_11064</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001637">
        <property type="protein sequence ID" value="OBZ80888.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MVU6"/>
    <dbReference type="STRING" id="101091.A0A1C7MVU6"/>
    <dbReference type="InParanoid" id="A0A1C7MVU6"/>
    <dbReference type="OrthoDB" id="6365676at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="119"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="28"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ80888.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="167" mass="19175" checksum="37A086C7B2266202" modified="2016-11-30" version="1">MSNNPRRVSKKSVDEVHPKPKLYAHQRIRSDPYKAERPLTIDQHLDKYYQQSTQHEQPQKYRYVPINIKKPAKRQQPQQPQEEESPVLFYQHKPLSYKRQINTPLHTLFPSTLLHPKLTSNSPSLSSPSSTNDTTSLDSSSFTSHTTDESSVQTGLLQLAHIVSTFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-06-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MVX5</accession>
    <name>A0A1C7MVX5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_10999</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001577">
        <property type="protein sequence ID" value="OBZ80952.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MVX5"/>
    <dbReference type="InParanoid" id="A0A1C7MVX5"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ80952.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="86" mass="9994" checksum="E187C4AC50E9E630" modified="2016-11-30" version="1">MTLFIGNEPSTNRIASLLGYRSSLRSFTGHSSQRQEVVKYDMLKTVAVLLAFGQTLNVYKTSFYNNRLFQSSLEFKRIHLRPEEFN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MXM4</accession>
    <name>A0A1C7MXM4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Endonuclease/exonuclease/phosphatase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_10379</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001143">
        <property type="protein sequence ID" value="OBZ81572.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MXM4"/>
    <dbReference type="STRING" id="101091.A0A1C7MXM4"/>
    <dbReference type="InParanoid" id="A0A1C7MXM4"/>
    <dbReference type="OrthoDB" id="2208330at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.10.10">
        <property type="entry name" value="Endonuclease/exonuclease/phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036691">
        <property type="entry name" value="Endo/exonu/phosph_ase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005135">
        <property type="entry name" value="Endo/exonuclease/phosphatase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03372">
        <property type="entry name" value="Exo_endo_phos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56219">
        <property type="entry name" value="DNase I-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Endonuclease/exonuclease/phosphatase" evidence="1">
        <location>
            <begin position="31"/>
            <end position="255"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03372"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ81572.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="415" mass="46968" checksum="121A9794A0AE975C" modified="2016-11-30" version="1">MAHLFSHDGVSLDTQFNNSDSSTKTFPLRIATLNFRGLRKSANPTTSSQFIRCIRTLSMDIIALQETHAVSADLESQFHMQFQAVDSIWTPHCGLVSFSPDLSFSQIVKSSCGRLITVTVSHKSDLFEPLSVTVLYAPADRKERYPFLQDLIHTLSSTTILPAQPLRHILLGDFNYSICSSVNARSRRSKAPTIWLNHIDHFYADAVTPRKQVAQATFSRGSSQSCIDYIYVSNDLHPNRMHGSVSYMNPTWTDHFLVKAHLQLLPSSVSNSLTQTGKGLWRAHPSLAKDPAFCERLASALSQTVSSFPEWYYPALQWESLKTTTRAVAQSYSRQKAFSLKKAEQTLQVKRRIVLKLIDRYPERAKDVSPHLHVIEGKLQQLQQYHTETLALRAGIRWRELGETSAGYLKRTYLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MXP2</accession>
    <name>A0A1C7MXP2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Serine/threonine-protein phosphatase</fullName>
            <ecNumber evidence="8">3.1.3.16</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">pzh1_1</name>
        <name evidence="10" type="ORF">A0J61_10764</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>O-phospho-L-seryl-[protein] + H2O = L-seryl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:20629"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="EC" id="3.1.3.16"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:47004"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="EC" id="3.1.3.16"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the PPP phosphatase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.16" evidence="8"/>
    <dbReference type="EMBL" id="LUGH01001377">
        <property type="protein sequence ID" value="OBZ81186.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MXP2"/>
    <dbReference type="STRING" id="101091.A0A1C7MXP2"/>
    <dbReference type="InParanoid" id="A0A1C7MXP2"/>
    <dbReference type="OrthoDB" id="1930084at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004722">
        <property type="term" value="F:protein serine/threonine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.21.10:FF:000212">
        <property type="entry name" value="Serine/threonine-protein phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050341">
        <property type="entry name" value="PP1_catalytic_subunit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006186">
        <property type="entry name" value="Ser/Thr-sp_prot-phosphatase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11668">
        <property type="entry name" value="SERINE/THREONINE PROTEIN PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11668:SF300">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00114">
        <property type="entry name" value="STPHPHTASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00156">
        <property type="entry name" value="PP2Ac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="Metallo-dependent phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00125">
        <property type="entry name" value="SER_THR_PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0464">Manganese</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0904">Protein phosphatase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Serine/threonine specific protein phosphatases" evidence="9">
        <location>
            <begin position="44"/>
            <end position="49"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00047761"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00048336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU004273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS00125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OBZ81186.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="242" mass="27684" checksum="CA6845A5DF8E8BB3" modified="2016-11-30" version="1">MTGFPPSSNYLFLGDYVDRGMYSLETILLLLCFKIKYPENFFLLRGNHESADVTRVYGFYDECKRRMSVKVWKCFVNVFNAMPIAALVGGRIFCVHGGLSPSMKSMEQISTIKRPIEIPEHGLLNDLLWSDPSDASPDWSENDRGVSICFGKRNVDAFLAKYDLDLICRAHMVVEDGYEFFNQRKLVTIFSAPNYCGEFDNYGAIMTISPELLCSFELLPPENKVVTREQQLKKHRSTLQLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MXT0</accession>
    <name>A0A1C7MXT0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_10351</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001131">
        <property type="protein sequence ID" value="OBZ81598.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MXT0"/>
    <dbReference type="InParanoid" id="A0A1C7MXT0"/>
    <dbReference type="OrthoDB" id="2276242at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ81598.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="73" mass="8372" checksum="CA40AE1594548925" modified="2016-11-30" version="1" fragment="single">MSHKTECPYTIRLFKPKGKNLFNLLDPKNENELCHNHPIDDLNLLSTSKGRKSILEVDDMRKISFGLEQNSSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MYN3</accession>
    <name>A0A1C7MYN3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Alkaline protease 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">alp1_3</name>
        <name evidence="7" type="ORF">A0J61_10004</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the peptidase S8 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000999">
        <property type="protein sequence ID" value="OBZ81947.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MYN3"/>
    <dbReference type="STRING" id="101091.A0A1C7MYN3"/>
    <dbReference type="InParanoid" id="A0A1C7MYN3"/>
    <dbReference type="OrthoDB" id="206201at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.200">
        <property type="entry name" value="Peptidase S8/S53 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000209">
        <property type="entry name" value="Peptidase_S8/S53_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036852">
        <property type="entry name" value="Peptidase_S8/S53_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023828">
        <property type="entry name" value="Peptidase_S8_Ser-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050131">
        <property type="entry name" value="Peptidase_S8_subtilisin-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43806:SF11">
        <property type="entry name" value="CEREVISIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43806">
        <property type="entry name" value="PEPTIDASE S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00082">
        <property type="entry name" value="Peptidase_S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52743">
        <property type="entry name" value="Subtilisin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51892">
        <property type="entry name" value="SUBTILASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00138">
        <property type="entry name" value="SUBTILASE_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 7" id="KW-0645">Protease</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0720">Serine protease</keyword>
    <feature type="domain" description="Peptidase S8/S53" evidence="6">
        <location>
            <begin position="6"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OBZ81947.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="117" mass="11560" checksum="38D656D3A212470F" modified="2016-11-30" version="1" fragment="single">PTCNSLPAANSNVYAVAASNKANRMASFSNYGSCTQIIAPGEDIKSTFATSSTATSVLSGTSMASPHTAGVAALLVDSLGRPSPAALYSALSSAATKNAITSVKSGTPNSLLYNGAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2024-01-24" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MZ58</accession>
    <name>A0A1C7MZ58_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_09888</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000964">
        <property type="protein sequence ID" value="OBZ82062.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MZ58"/>
    <dbReference type="InParanoid" id="A0A1C7MZ58"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="29"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="104"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ82062.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="104" mass="12237" checksum="28BCFE85C2EA90B3" modified="2016-11-30" version="1" fragment="single">MSLRWDKNQFALTLKEYLRQEKTCKAQIISDNDMDTSSDDHMEDDKQEEMEIEHFSLSEEWMEKIRRIGNDSVSYLTLENDAMLLSQASRICLGPEDCTNFDSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MZG6</accession>
    <name>A0A1C7MZG6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_11427</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01002023">
        <property type="protein sequence ID" value="OBZ80524.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MZG6"/>
    <dbReference type="STRING" id="101091.A0A1C7MZG6"/>
    <dbReference type="InParanoid" id="A0A1C7MZG6"/>
    <dbReference type="OrthoDB" id="2289822at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="68"/>
            <end position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ80524.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="281" mass="33160" checksum="1B6094A39EFEF135" modified="2016-11-30" version="1">MRIWTMNNHLAVEHVPELIRQQGPLRYFSCRSLERTIKKYSNMANSMSAPDVEISNIHNRVNYYKEHRSTEESESFMASSSTRERDSLLHPTQPDTTPRLWSKIIHLELRERADFFGASTWQFINALQRYYSRLGLSGSVIDSQQIIMAGSMLKEEVCFHSRMHRSNNSLLKRSNHLIFNIRYWYVGEVLMYFEHKLNGTSRFLALASVMPDASMDEYGIIRVTYDQQRLNEQFMVCNTLDVITIIGLVRYNDNETDFKAIWPDAKYYQKLDGRIYREELL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MZV7</accession>
    <name>A0A1C7MZV7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_09515</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000867">
        <property type="protein sequence ID" value="OBZ82435.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MZV7"/>
    <dbReference type="STRING" id="101091.A0A1C7MZV7"/>
    <dbReference type="InParanoid" id="A0A1C7MZV7"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="21"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="37"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ82435.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="55" mass="6610" checksum="384C82517D59DEDC" modified="2016-11-30" version="1" fragment="single">VKEQEQEDMVDAQGNTIKAVEKKKKLTSKELRKKKKDRMERRKRGEEVYTTDEEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N033</accession>
    <name>A0A1C7N033_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="9">L-ascorbate oxidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">AAO_1</name>
        <name evidence="9" type="ORF">A0J61_09447</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the multicopper oxidase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000852">
        <property type="protein sequence ID" value="OBZ82505.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N033"/>
    <dbReference type="STRING" id="101091.A0A1C7N033"/>
    <dbReference type="InParanoid" id="A0A1C7N033"/>
    <dbReference type="OrthoDB" id="2121828at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005507">
        <property type="term" value="F:copper ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04206">
        <property type="entry name" value="CuRO_1_LCC_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd04205">
        <property type="entry name" value="CuRO_2_LCC_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.420">
        <property type="entry name" value="Cupredoxins - blue copper proteins"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011707">
        <property type="entry name" value="Cu-oxidase-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001117">
        <property type="entry name" value="Cu-oxidase_2nd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011706">
        <property type="entry name" value="Cu-oxidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045087">
        <property type="entry name" value="Cu-oxidase_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008972">
        <property type="entry name" value="Cupredoxin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11709:SF394">
        <property type="entry name" value="FI03373P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11709">
        <property type="entry name" value="MULTI-COPPER OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00394">
        <property type="entry name" value="Cu-oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07731">
        <property type="entry name" value="Cu-oxidase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07732">
        <property type="entry name" value="Cu-oxidase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49503">
        <property type="entry name" value="Cupredoxins"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0186">Copper</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Plastocyanin-like" evidence="8">
        <location>
            <begin position="45"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="domain" description="Plastocyanin-like" evidence="6">
        <location>
            <begin position="180"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="domain" description="Plastocyanin-like" evidence="7">
        <location>
            <begin position="460"/>
            <end position="587"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="339"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="343"/>
            <end position="361"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00394"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF07731"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF07732"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OBZ82505.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="598" mass="68337" checksum="34C57665FF5A5717" modified="2016-11-30" version="1">MKIILLLVYLKMLLLSLAYLLIAVISPVLLWPDQENDVKEIRLHIQRANLNPDCFHQSYSAFHVNGQFPAPPIRVVRGDRVRLIVENDASNNVSTAIHVHGIYQYYSNHADGVSEINQVAIRPGKRFVQEFRVINQTGTFFYHAHVATQDDSVQGPFIVYDSQASLEGKTSDGPYPYDHEHILQWSDWWHQSLDDRADYYMSPSFGNDQGPDSVLLNGQGVYPNVTITEDCKGYRYFDVFPNRLYRLRNIGGMTFRDLEISIRDHGMQLIEIDGEYVKPYNLSSIQIGPGQRMSVLVRTANHPPGSLFPILTQYRWRQDALNPGYTESGYGYLRYVEPDQEDDCKSQPEEKTEGPTQEKDRIRILERPQTPAYNASDQVPGWVLPYIRPWKRPSSSSILTAKADRTILISMRDIRLPDGSRRFVNEDRPYNPHPWGNASVSLLDIVRKDPEVGTLARHDGYSSRHRTYPLKLNQIVDLVFQNYFLPPPAPPNLCVLHPWHTHGYSHYLMAEGPGDYDPVVHKDLVTFAQPLFKDVSVVYPVPKNGSEGCGWTKVRIFTNNPGVWAVHCHITSHMMQGKMIVLEVAPEKLVSKKEKTSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N061</accession>
    <name>A0A1C7N061_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Protein DML1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">DML1</name>
        <name evidence="7" type="ORF">A0J61_09463</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Involved in the partitioning of the mitochondrial organelle and mitochondrial DNA (mtDNA) inheritance.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the misato family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000856">
        <property type="protein sequence ID" value="OBZ82487.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N061"/>
    <dbReference type="FunCoup" id="A0A1C7N061">
        <property type="interactions" value="243"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N061"/>
    <dbReference type="InParanoid" id="A0A1C7N061"/>
    <dbReference type="OrthoDB" id="271881at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007005">
        <property type="term" value="P:mitochondrion organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06060">
        <property type="entry name" value="misato"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1440">
        <property type="entry name" value="Tubulin/FtsZ, GTPase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013838">
        <property type="entry name" value="Beta-tubulin_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049942">
        <property type="entry name" value="DML1/Misato"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029209">
        <property type="entry name" value="DML1/Misato_tubulin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019605">
        <property type="entry name" value="Misato_II_tubulin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036525">
        <property type="entry name" value="Tubulin/FtsZ_GTPase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13391">
        <property type="entry name" value="MITOCHONDRIAL DISTRIBUTION REGULATOR MISATO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13391:SF0">
        <property type="entry name" value="PROTEIN MISATO HOMOLOG 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10644">
        <property type="entry name" value="Misat_Tub_SegII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14881">
        <property type="entry name" value="Tubulin_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52490">
        <property type="entry name" value="Tubulin nucleotide-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00228">
        <property type="entry name" value="TUBULIN_B_AUTOREG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Misato Segment II tubulin-like" evidence="5">
        <location>
            <begin position="2"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="domain" description="DML1/Misato tubulin" evidence="6">
        <location>
            <begin position="132"/>
            <end position="319"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003757"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008507"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF10644"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF14881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OBZ82487.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="505" mass="58023" checksum="B685CF4A784BE040" modified="2016-11-30" version="1">MREIITLQLGSIANHVGTHFWNAQEEYFSRSTEKDEIDHQVLYRQGETANGEATYAPRTLIYDLKGGFGSMQKYNKLFGGDLAGEEEPGILWEQGIHRINRSLSKSKYQQELDRMELENDVCMDPDVLDQLNDSVNNWSDYNRIYYHPRSINPIVTHQMDNEITPFDNFTIGRQAYVENEKETETFEENFRFFVEECDSLQGFQLFTDVDDGFGGFTEGLLNNIRDEFAKTPILTYGLSDSFAQHRTERHKQKIMLNRSLSLTRLSELSSLYVPIYTPTLKSVQQSGLASFLKFNELSRYHTSAIIAAAIETNSLPYRLKQNPITLADTIGKLNWARNTNLASLSVCLPLPISKQGYHHTLSLLNQPKQLLPIMPLLSRLEKEDKVIYGEVVVARGLSNKMQQQEPYLEALYTNFKDGNDPLQSRYSLESTLPLPDSFPRIFQQFDQEGLLDPSIGQEIVPEEIPSLVHLSSGTQLKATIDQHIRHLQQTHLKDFWEYTQGEFMI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N0U7</accession>
    <name>A0A1C7N0U7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_10977</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001556">
        <property type="protein sequence ID" value="OBZ80974.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N0U7"/>
    <dbReference type="STRING" id="101091.A0A1C7N0U7"/>
    <dbReference type="InParanoid" id="A0A1C7N0U7"/>
    <dbReference type="OrthoDB" id="2285201at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46579">
        <property type="entry name" value="F5/8 TYPE C DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46579:SF1">
        <property type="entry name" value="F5_8 TYPE C DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ80974.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="411" mass="46797" checksum="C6EA6FCD7C054BAC" modified="2016-11-30" version="1">MIQSLPREIRNLRTNTILVCLINGPKEPKTYEMNHHLRPLTKTRGKQVVKAALFLCMMDLPAQRKVAGFTSFNSINARHKCKKQFEPIVAGGKARDFTDFDVDNWTGVASTKNSSLPIMLSPADLKELQAILETKLVLASGHAVPSIARKLPIGKDFCNFKAEEWTTWLLILSPYLLAQRLTTEAHNHWMFLVKASRIFLSSSLTMSELDEAQELMKAFLVGFEAVYDDKFLITSNIHNALHLREATLDYSASPSHWLFNFEGYNQDIKRIRTNRKGCVERTYIKRFLIQVHAKDNAESLLDDILAEFKERFITGTEYSYGFEQLPPKAYLSINPKLGKLSPNVSTCLINYYNAVHCLTFVDAQFSFANPESLPVDWCATKFKNIDILGNKYTSTKASRLKNRDSKALAYH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N0Z9</accession>
    <name>A0A1C7N0Z9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Cell division control protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">Cdc6</name>
        <name evidence="10" type="ORF">A0J61_09171</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the CDC6/cdc18 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000789">
        <property type="protein sequence ID" value="OBZ82777.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N0Z9"/>
    <dbReference type="FunCoup" id="A0A1C7N0Z9">
        <property type="interactions" value="501"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N0Z9"/>
    <dbReference type="InParanoid" id="A0A1C7N0Z9"/>
    <dbReference type="OrthoDB" id="1926878at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003688">
        <property type="term" value="F:DNA replication origin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006270">
        <property type="term" value="P:DNA replication initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033314">
        <property type="term" value="P:mitotic DNA replication checkpoint signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00009">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000547">
        <property type="entry name" value="Cell division control protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049945">
        <property type="entry name" value="AAA_22"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016314">
        <property type="entry name" value="Cdc6/18"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015163">
        <property type="entry name" value="Cdc6_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054425">
        <property type="entry name" value="Cdc6_ORC1-like_ATPase_lid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050311">
        <property type="entry name" value="ORC1/CDC6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10763:SF26">
        <property type="entry name" value="CELL DIVISION CONTROL PROTEIN 6 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10763">
        <property type="entry name" value="CELL DIVISION CONTROL PROTEIN 6-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13401">
        <property type="entry name" value="AAA_22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22606">
        <property type="entry name" value="Cdc6-ORC-like_ATPase_lid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09079">
        <property type="entry name" value="WHD_Cdc6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001767">
        <property type="entry name" value="Cdc6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="3 10" id="KW-0132">Cell division</keyword>
    <keyword evidence="4" id="KW-0235">DNA replication</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="9">
        <location>
            <begin position="121"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="46"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="59"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRNR" id="PIRNR001767"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OBZ82777.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="499" mass="55730" checksum="65A0428E31FF1BA5" modified="2016-11-30" version="1">MLRRTRSSGRLSDKESPMKPSKRGRKRTNTDDLENVSVIPEKKAKTTTSSEQHNQSNETQPPTQPTTTCQDQDKTVPLEGTLYQRAKAMFRRTAIPSQLIGRESERERMIAFWKEHVLSNKSGCLYISGKPGTGKTAMLNEIMRSMQQENQKASHQIKVVNINCMSMKEPKQIYEKLIQELSSKQSKVLESDVAKQAQALIDAKRDILSVVVLDEIDYLKTKDQDVLYKLFEWTSLPQSQLVLIGISNALDLTDRILPRLRAKNCEPILLNFNSYGNEEIQNIIKGRLYALLEEGTVTQDTPLPLIQPIAIKLIASKVAGSASDVRTALDICLKAVEIAEAEHKKKSANGVLGEIESNTQNKTTTEEPKVTIAHVSRVLKVVSGKSSAQKLKELKLHEKIALGVLLVMHRSNKGSKKNQSTIRDFKEHYVKSCANSTNIPTVSSNELNDILNALETKSLVTLTKSKDSTKVQLGVQESEILDVINESSVLKAWMEEVVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N144</accession>
    <name>A0A1C7N144_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Copper transport protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">CTR2_0</name>
        <name evidence="5" type="ORF">A0J61_10876</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the copper transporter (Ctr) (TC 1.A.56) family. SLC31A subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001474">
        <property type="protein sequence ID" value="OBZ81074.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N144"/>
    <dbReference type="FunCoup" id="A0A1C7N144">
        <property type="interactions" value="167"/>
    </dbReference>
    <dbReference type="InParanoid" id="A0A1C7N144"/>
    <dbReference type="OrthoDB" id="161814at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005375">
        <property type="term" value="F:copper ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007274">
        <property type="entry name" value="Cop_transporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12483:SF115">
        <property type="entry name" value="COPPER TRANSPORT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12483">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 31 COPPER TRANSPORTERS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04145">
        <property type="entry name" value="Ctr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0186">Copper</keyword>
    <keyword evidence="4" id="KW-0187">Copper transport</keyword>
    <keyword evidence="4" id="KW-0406">Ion transport</keyword>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="40"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="119"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="145"/>
            <end position="162"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU367022"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OBZ81074.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="175" mass="20263" checksum="D71F3B8FCBD4382E" modified="2016-11-30" version="1">MEDHTGHHDMPSGHHDMPATCSMNMLFNWQIENTCVVFRWWHISGAFSMLFSCIAIFLIAAGYEWMRVYSIQLEQQWKEAESLLQRQSVDDREELGLGEQRSLVHAYQQYNRLSSNRRLIQSSIYALLVAISFWLMLVFMTYNGYLMIATVLGAGFGHFIFGQGRLTGDKSIQCH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N179</accession>
    <name>A0A1C7N179_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_09201</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000796">
        <property type="protein sequence ID" value="OBZ82748.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="InParanoid" id="A0A1C7N179"/>
    <dbReference type="OrthoDB" id="2243575at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="116"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="116"/>
            <end position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ82748.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="517" mass="59212" checksum="0099356F92D977BF" modified="2016-11-30" version="1">MPVQQGRKAFFSDKCAEDWNFMEYFACTHNKQKELKKYNAIKKDFLDDLQWIAQSGAPQEVLSYVSELKQSIPDKAAVKAARAKARPNFQINYQSICINGNNNVVRDIAFDAKKDDKITSSSKGKEKEDEASSSKRKVEVEEDQESVGNKKGKTERQETSSIWKDWVVFLHNNENKFHPYSNEFHDVIRAGFNVSWKPNLDKALFEKHXAQKEDKQHPLPETTAEYINSVVDSTELKEFKNNMQSTPLEEDQVSFDFLEELFRAYYYIYNSKQDIKASEAVFNNMLIFPFLKAVAFAVAEETSSSAESVVGETPLVSMKKQLKEDESANLYLADGLIRLYGLKNLELLLLETSSCFSCKDRAKGSFDHHKGVFGALSMMKAAADEFYLAKVNTFGKLKILFLHAFGNTLYLWSLHYVEEGPLYELWLEASLEICPRFEDAIEHLPKAIAFFWKMKCLVKEGVEVLLELQNEHKTKLKQCRFNSGPVENLTHIINPTIMKLNEAEDKAGMADLGPFFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N1N6</accession>
    <name>A0A1C7N1N6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Calmodulin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">CALM_2</name>
        <name evidence="6" type="ORF">A0J61_08897</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000731">
        <property type="protein sequence ID" value="OBZ83055.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N1N6"/>
    <dbReference type="STRING" id="101091.A0A1C7N1N6"/>
    <dbReference type="InParanoid" id="A0A1C7N1N6"/>
    <dbReference type="OrthoDB" id="26525at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016460">
        <property type="term" value="C:myosin II complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.238.10:FF:000181">
        <property type="entry name" value="CALML5 isoform 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.238.10:FF:000251">
        <property type="entry name" value="Calmodulin-related protein 97A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050230">
        <property type="entry name" value="CALM/Myosin/TropC-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23048:SF0">
        <property type="entry name" value="CALMODULIN LIKE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23048">
        <property type="entry name" value="MYOSIN LIGHT CHAIN 1, 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13499">
        <property type="entry name" value="EF-hand_7"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00054">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0106">Calcium</keyword>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="EF-hand" evidence="5">
        <location>
            <begin position="8"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="5">
        <location>
            <begin position="44"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="5">
        <location>
            <begin position="80"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="5">
        <location>
            <begin position="116"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="102"/>
            <end position="129"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OBZ83055.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="148" mass="16155" checksum="28227383F4626275" modified="2016-11-30" version="1">MSDQLTPEQIAEYREAFHLFDADGSGSISASELGTVLRSFGMNPSDAELQDMVNDVDADGNGTIDFEEFLGLVKNLQSENDTDDLHEAFKVFDADGNGVIDRSELQKVMSSLNENLSEAELDAMIQEADIDGNGTISFEEFKAMMSGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N2H5</accession>
    <name>A0A1C7N2H5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">DNA sliding clamp PCNA</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">pcn1</name>
        <name evidence="11" type="ORF">A0J61_08761</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand. Involved in DNA repair.</text>
    </comment>
    <comment type="function">
        <text evidence="7">This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processivity during elongation of the leading strand.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the PCNA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000706">
        <property type="protein sequence ID" value="OBZ83188.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N2H5"/>
    <dbReference type="FunCoup" id="A0A1C7N2H5">
        <property type="interactions" value="785"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N2H5"/>
    <dbReference type="InParanoid" id="A0A1C7N2H5"/>
    <dbReference type="OrthoDB" id="534348at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000785">
        <property type="term" value="C:chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000781">
        <property type="term" value="C:chromosome, telomeric region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043596">
        <property type="term" value="C:nuclear replication fork"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005654">
        <property type="term" value="C:nucleoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043626">
        <property type="term" value="C:PCNA complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035861">
        <property type="term" value="C:site of double-strand break"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030337">
        <property type="term" value="F:DNA polymerase processivity factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042802">
        <property type="term" value="F:identical protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070987">
        <property type="term" value="P:error-free translesion synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042276">
        <property type="term" value="P:error-prone translesion synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034087">
        <property type="term" value="P:establishment of mitotic sister chromatid cohesion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006272">
        <property type="term" value="P:leading strand elongation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035753">
        <property type="term" value="P:maintenance of DNA trinucleotide repeats"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000710">
        <property type="term" value="P:meiotic mismatch repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:1903459">
        <property type="term" value="P:mitotic DNA replication lagging strand elongation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006289">
        <property type="term" value="P:nucleotide-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045739">
        <property type="term" value="P:positive regulation of DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045740">
        <property type="term" value="P:positive regulation of DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030466">
        <property type="term" value="P:silent mating-type cassette heterochromatin formation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031509">
        <property type="term" value="P:subtelomeric heterochromatin formation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070914">
        <property type="term" value="P:UV-damage excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd00577">
        <property type="entry name" value="PCNA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.150.10:FF:000006">
        <property type="entry name" value="Proliferating cell nuclear antigen"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.150.10:FF:000008">
        <property type="entry name" value="Proliferating cell nuclear antigen"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.70.10.10:FF:000001">
        <property type="entry name" value="Proliferating cell nuclear antigen"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.150.10">
        <property type="entry name" value="DNA Polymerase III, subunit A, domain 2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00317">
        <property type="entry name" value="DNApol_clamp_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046938">
        <property type="entry name" value="DNA_clamp_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000730">
        <property type="entry name" value="Pr_cel_nuc_antig"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022649">
        <property type="entry name" value="Pr_cel_nuc_antig_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022659">
        <property type="entry name" value="Pr_cel_nuc_antig_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022648">
        <property type="entry name" value="Pr_cel_nuc_antig_N"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00590">
        <property type="entry name" value="pcna"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11352">
        <property type="entry name" value="PROLIFERATING CELL NUCLEAR ANTIGEN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11352:SF0">
        <property type="entry name" value="PROLIFERATING CELL NUCLEAR ANTIGEN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02747">
        <property type="entry name" value="PCNA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00705">
        <property type="entry name" value="PCNA_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00339">
        <property type="entry name" value="PCNACYCLIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55979">
        <property type="entry name" value="DNA clamp"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01251">
        <property type="entry name" value="PCNA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00293">
        <property type="entry name" value="PCNA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 8" id="KW-0235">DNA replication</keyword>
    <keyword evidence="4 8" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5 7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Proliferating cell nuclear antigen PCNA N-terminal" evidence="9">
        <location>
            <begin position="1"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="domain" description="Proliferating cell nuclear antigen PCNA C-terminal" evidence="10">
        <location>
            <begin position="127"/>
            <end position="254"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00054163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003671"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF02747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="OBZ83188.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="259" mass="28486" checksum="019A8A12DCC2DD5B" modified="2016-11-30" version="1">MLEARLQQAKLLKSLLEAIKELVTECNFECNDSGIALQAMDNSHVALVAMLLRSDGFDPYRCDRNLPLGINLTNLGKILKCARNDDILTIKADDDGDALTMIFESKDSDKISEYDLKLMDIDSEHLGIPETAYEAVITMSSARFQEICRDLSGLSDSVTIECTKEGVKFSSDGEIGKGAITLKANSSVDDDDDATVIELQQAVSMTFSIKYLVNFTKATPLSSRVSLNMSADVPLLVDYKLDNLGYVRYYLAPKIGDEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N388</accession>
    <name>A0A1C7N388_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">YMC020W-like alpha/beta hydrolase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_08400</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000642">
        <property type="protein sequence ID" value="OBZ83551.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N388"/>
    <dbReference type="InParanoid" id="A0A1C7N388"/>
    <dbReference type="OrthoDB" id="5598028at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058934">
        <property type="entry name" value="YMC020W-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058933">
        <property type="entry name" value="YMC020W-like_ab_hydrolase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47349:SF1">
        <property type="entry name" value="AER328WP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47349">
        <property type="entry name" value="CHROMOSOME 8, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26147">
        <property type="entry name" value="AB_HYDROLASE_YMC0-YMC35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="YMC020W-like alpha/beta hydrolase" evidence="2">
        <location>
            <begin position="120"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="19"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF26147"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ83551.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="532" mass="60877" checksum="15EC367A66979AC8" modified="2016-11-30" version="1">MSNNKRRSSTESSNALSNEIEKRPRSETTDSWIDWLKSNISLTTLSPTISAEQEEQQQEEEEIVDESVEQTKQSVWSWLGYGLTAKEGSRESITTDNVVLPLFDTQFKPASVSTSLFSKTVQAIQSVLFQQKKPTQSIIDSLRENPEKRIVVIGVHGWFPMKLVRSMMGEPTGTSAKFCQQMILAIQTYFKEGYEWNIPDHMITAIPLTWEGKVLERVEHLYKLILDTWADTLRSADIVVWATHSQGTPVSTILLQRLIQESLVDPKRQPICMLAMAGISHGPFPTLKTSVFVKYFEADAARELFEFMKSDTPISTQYHEAMVFILQQRIKVVFVGSMQDQVVPLYSAIMSGISHPNILRAVYMDGHVYAPDDFLIRLISFAIQLLNLGLSDHGFLIHISEVLAGNLYALEGGHSTIYEELKVFQLPLRYLFEASPCGQLELPRVYLEDDKKKQRVIEQVEARLDPFNAKARLNPFHLPWAMRGIWDDPRILQNDQLRTELETLQTLFEQWNPSSARLKEIKFRLEPLKARL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N3G4</accession>
    <name>A0A1C7N3G4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Methyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_10078</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001023">
        <property type="protein sequence ID" value="OBZ81874.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N3G4"/>
    <dbReference type="FunCoup" id="A0A1C7N3G4">
        <property type="interactions" value="432"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N3G4"/>
    <dbReference type="InParanoid" id="A0A1C7N3G4"/>
    <dbReference type="OrthoDB" id="2257279at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041698">
        <property type="entry name" value="Methyltransf_25"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13649">
        <property type="entry name" value="Methyltransf_25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Methyltransferase" evidence="2">
        <location>
            <begin position="88"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="7"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="18"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ81874.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="320" mass="36607" checksum="D85FC766D0F52363" modified="2016-11-30" version="1">MGNQLSTKRKIPTKKKASSSISSGTYSDSFHTDDQSSSSGQPKFLIDLYTSRADEVYHKNEHYLIKHLFQRNYFAPIENALTQPGSAVLDVGCGYHASWLLDMAVEFPQCAFHGFDLVEPLANVKPANLIPSNCFLKKHDLFDGFPYDDNQFDYIHQSQMQMVYPADKVSWMLEEFVRMTKENGMVELVESDIIPKRMGPLFERLFDGVRLFIREYFGTPFHGPCLVKRMSEAGLVDIQTDYGSLPLCWGGYIGKLVYEDTLRMFKLAGSTLAPYMGYEGEYDPVEFENFLDKAFDECVEYQTYFNVRWACGRKPASNLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N3H9</accession>
    <name>A0A1C7N3H9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">RING finger protein B</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">rngB_2</name>
        <name evidence="5" type="ORF">A0J61_08274</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000622">
        <property type="protein sequence ID" value="OBZ83672.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N3H9"/>
    <dbReference type="STRING" id="101091.A0A1C7N3H9"/>
    <dbReference type="InParanoid" id="A0A1C7N3H9"/>
    <dbReference type="OrthoDB" id="432528at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12087">
        <property type="entry name" value="TM_EGFR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.80">
        <property type="entry name" value="Kelch-type beta propeller"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015915">
        <property type="entry name" value="Kelch-typ_b-propeller"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46093:SF3">
        <property type="entry name" value="ACYL-COA-BINDING DOMAIN-CONTAINING PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46093">
        <property type="entry name" value="ACYL-COA-BINDING DOMAIN-CONTAINING PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24681">
        <property type="entry name" value="Kelch_KLHDC2_KLHL20_DRC7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117281">
        <property type="entry name" value="Kelch motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0880">Kelch repeat</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008889455" evidence="4">
        <location>
            <begin position="17"/>
            <end position="669"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="386"/>
            <end position="407"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OBZ83672.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="669" mass="74204" checksum="1E1B70291F859394" modified="2016-11-30" version="1">MKQMFVLLLLSLLAVGAIDPGMIPIPGKPVYIKKSNTLWIFSFSRNAQAGNKLSFIDLNQSFDTLYPPVVDRSSFITNNQCPVMHFAQALPSADGVSINIFGAGSDLNGSYESTMTVCQFNTETHAWKQIQSSGNLPLARRNAALEFTNSNLTWFFGGSSDPFTGLASSTQLSHYWHQDTSIYDSSSQVWITGPEYNGHPRANATMTQISDTNGQLIIVGGSVINNLSAVDMVTNHPLANMSDIVVLDPRTSIWSDVKAYGDNIPFGRKHHTTTLHPDGRTLVVIGGELFNSTGAYLLNDVWLLDTRNMNNLTWTQPEVHGQGFFRSNHTSILIDDQIWVIAGTNQSSKAVDIQLLNLTSWTWSQSAIYISPPPVAFAQIGGLKGLIGLIVGIVVAILLVIGCVVFWRYRQQKKAKAFPIQHKDSASLDSANYEYEIAQTMPPVIDDHSKIFVPRTSISNMAARASIDYNPNTLHSHVSSYGNGGLQIDTNHAYMHPYNTMDQAQVSSSSASYPERHFDDNYLTNENDNMYTMDQTNNGHYAYGSEFSNSNTTHPSKQSLGYWESPTAIPTHQINNPRQLFYVNHASLMTTNYFLMPSSNRNEERVFFKNQNSLHQLQKPNEIDHMVGETMTDTVCSSTTDEDTSSSATPIVSNELLCKTMPVVFEGKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N4D8</accession>
    <name>A0A1C7N4D8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_07990</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000577">
        <property type="protein sequence ID" value="OBZ83960.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N4D8"/>
    <dbReference type="InParanoid" id="A0A1C7N4D8"/>
    <dbReference type="OrthoDB" id="2288752at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ83960.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="311" mass="34965" checksum="47CDAA2C25636242" modified="2016-11-30" version="1">MLRVYSVLYIERLWNHSLSSDVVKQVPVKTTYGTEREITEPLTVSEQIIENVDNQQEVYPSKEQEIVVVEEQKVASTSESIAEVEEEIVHELSVAEEIEPVVETPIEEEPIVEIAIVETPIEEVSIVEEVSIVEEVPIVETAVEVPVIEESMAIKEPEMVDEELMIEIIQESPIQDLIEEVVPVQEEKQIITTLAINTDRYNQISTIIESPGEDIYSAGVADHSTSVSSSSSILSPLTPTSVQSSGFHSSQVLEDIEFEKKVQALPAPQPRKRTTSLFKRETDKINDKRKSLTKKLKRALTVKAENKRYSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N4V3</accession>
    <name>A0A1C7N4V3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative zinc-type alcohol dehydrogenase-like protein YogA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">yogA_0</name>
        <name evidence="2" type="ORF">A0J61_07804</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000549">
        <property type="protein sequence ID" value="OBZ84143.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N4V3"/>
    <dbReference type="STRING" id="101091.A0A1C7N4V3"/>
    <dbReference type="InParanoid" id="A0A1C7N4V3"/>
    <dbReference type="OrthoDB" id="449487at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05188">
        <property type="entry name" value="MDR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="ER"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052711">
        <property type="entry name" value="Zinc_ADH-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45033">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45033:SF3">
        <property type="entry name" value="DEHYDROGENASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G13270)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Enoyl reductase (ER)" evidence="1">
        <location>
            <begin position="19"/>
            <end position="341"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ84143.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="352" mass="38489" checksum="33E7BE9D7F6858FB" modified="2016-11-30" version="1">MVSAFLTENAPNKTKLKHGVVFKENKFTEPKENQSIVQIRAASFNHRDVWILNGVYPSVEYGSILGSDAVAYITKSNSENLSVGQRVLINPGYGWKSDPRGPEDKFYILGLPPTMGTMTEEPIAVDNDELVSCPEHLTHAEAASLPLAGLTAYRALFTQSLVREGDYVLITGIGGGVALFALQFAVAIGAHVYVTSSSQEKIDKAIKMGAKGGVNYKNENFIDELKHQLNGNKLSAIVDGAGGPLYAALPELMRPGGIIANYGHTATPEGVTFNMDHVRENLVWKGSTMGSRREFIEMVKLVEEKKIKPVVSHVWSGLNSDTFDKAINVMNNGHQFGKIVLEFNEHLDKNKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N4Y7</accession>
    <name>A0A1C7N4Y7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">RNA pyrophosphohydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">rppH</name>
        <name evidence="4" type="ORF">A0J61_07754</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the Nudix hydrolase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000542">
        <property type="protein sequence ID" value="OBZ84205.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N4Y7"/>
    <dbReference type="STRING" id="101091.A0A1C7N4Y7"/>
    <dbReference type="InParanoid" id="A0A1C7N4Y7"/>
    <dbReference type="OrthoDB" id="414075at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.79.10">
        <property type="entry name" value="Nucleoside Triphosphate Pyrophosphohydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020476">
        <property type="entry name" value="Nudix_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015797">
        <property type="entry name" value="NUDIX_hydrolase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020084">
        <property type="entry name" value="NUDIX_hydrolase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000086">
        <property type="entry name" value="NUDIX_hydrolase_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00293">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00502">
        <property type="entry name" value="NUDIXFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55811">
        <property type="entry name" value="Nudix"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51462">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00893">
        <property type="entry name" value="NUDIX_BOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 2 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nudix hydrolase" evidence="3">
        <location>
            <begin position="3"/>
            <end position="111"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003476"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OBZ84205.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="111" mass="12617" checksum="F6C5E384B5155BF5" modified="2016-11-30" version="1">MNGTYRAVSSIVLRRLPSKEIAHQDTNLKDIYRKPTELLYLVVKKPRVDHAWQFPQGGQDPGETGPEAALRELREECGSDLQVNLIDTVHEAGIYQYPFPAHFKRSIILSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N596</accession>
    <name>A0A1C7N596_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 6">N-acetylglucosamine-6-phosphate deacetylase</fullName>
            <ecNumber evidence="1 6">3.5.1.25</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">amdhd2</name>
        <name evidence="12" type="ORF">A0J61_08124</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5 6">
            <text>N-acetyl-D-glucosamine 6-phosphate + H2O = D-glucosamine 6-phosphate + acetate</text>
            <dbReference type="Rhea" id="RHEA:22936"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:30089"/>
            <dbReference type="ChEBI" id="CHEBI:57513"/>
            <dbReference type="ChEBI" id="CHEBI:58725"/>
            <dbReference type="EC" id="3.5.1.25"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="9">
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </cofactor>
        <text evidence="9">Binds 1 divalent metal cation per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the metallo-dependent hydrolases superfamily. NagA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.5.1.25" evidence="1 6"/>
    <dbReference type="EMBL" id="LUGH01000598">
        <property type="protein sequence ID" value="OBZ83829.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N596"/>
    <dbReference type="STRING" id="101091.A0A1C7N596"/>
    <dbReference type="InParanoid" id="A0A1C7N596"/>
    <dbReference type="OrthoDB" id="10264777at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008448">
        <property type="term" value="F:N-acetylglucosamine-6-phosphate deacetylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006046">
        <property type="term" value="P:N-acetylglucosamine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.140">
        <property type="entry name" value="Metal-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006680">
        <property type="entry name" value="Amidohydro-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003764">
        <property type="entry name" value="GlcNAc_6-P_deAcase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11113">
        <property type="entry name" value="N-ACETYLGLUCOSAMINE-6-PHOSPHATE DEACETYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11113:SF14">
        <property type="entry name" value="N-ACETYLGLUCOSAMINE-6-PHOSPHATE DEACETYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01979">
        <property type="entry name" value="Amidohydro_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF038994">
        <property type="entry name" value="NagA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="Metallo-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="4 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="10">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008889483" description="N-acetylglucosamine-6-phosphate deacetylase" evidence="10">
        <location>
            <begin position="22"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="domain" description="Amidohydrolase-related" evidence="11">
        <location>
            <begin position="6"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor/acceptor" evidence="7">
        <location>
            <position position="227"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="52"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="63"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="124"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="145"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="148"/>
            <end position="149"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="156"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="205"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="262"/>
            <end position="264"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00018029"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00047647"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRNR" id="PIRNR038994"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR038994-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR038994-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR038994-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF01979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="OBZ83829.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="340" mass="36001" checksum="BCCE4C96031B2E34" modified="2016-11-30" version="1">MGLMGLLRFGCTAFCPTVVSSSSEVYEKVLPLLKRRKGSATGGAEILGAHLEGPFISVLKKGAHNQSVFKVAKNGIADFDKTYGAELKKGSQTVSIITIAPELEGACDAIPDLVSRGITVAMGHSACRIAEAEKAVTKGANSITHLFNAMQAFHHRDPGLVGVLGASDLPSPEKKSRYPKSSVSSPNRSELDPRPFYGLICDGVHVHPNSIRIAYCSHPSGAVLVTDTLSAMGLPKGVYVLGGKEVEVDEKGGAYVKGTKTLAGSTITIDQCIRNFQKFTNCSLVEAIEAATLHPAQMLGIDHRKGTLNAGADADFVFLDDSSGEVYVKRVFVAGEEVQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N5G7</accession>
    <name>A0A1C7N5G7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Vacuolar membrane amino acid uptake transporter fnx2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">fnx2_1</name>
        <name evidence="8" type="ORF">A0J61_07614</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000523">
        <property type="protein sequence ID" value="OBZ84340.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N5G7"/>
    <dbReference type="STRING" id="101091.A0A1C7N5G7"/>
    <dbReference type="InParanoid" id="A0A1C7N5G7"/>
    <dbReference type="OrthoDB" id="3437016at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000329">
        <property type="term" value="C:fungal-type vacuole membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015174">
        <property type="term" value="F:basic amino acid transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1720.10">
        <property type="entry name" value="Multidrug resistance protein D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501:SF191">
        <property type="entry name" value="VACUOLAR BASIC AMINO ACID TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="124"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="150"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="182"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="209"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="251"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="281"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="319"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="355"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="386"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="410"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="449"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="520"/>
            <end position="541"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="59"/>
            <end position="542"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OBZ84340.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="550" mass="60217" checksum="5A920A959C09869D" modified="2016-11-30" version="1">MAVKERTPLIHSQSSSSATIVIEDGENYGSLSKTLEEGQSKDDWEPHLGNISLTMIADANASLSTGAFLAALDTSIVVTIFNEIGTEFQSSNLSVWIMTSYMLSTSAVQPLYGKLSDIYGRKTTLVTIVCFFLLGSLLCGAAGSMVQLSIARAIAGLGGGGIMTMASVVIHDLVPMRQRGQYQAYVNMAQTIGTTVGAPLGGMINDTLGWRYCFYINIPFCLFILYCYVYRLENYNLDKKQEPASLGQIDMVGALLLLMANVCFVTSTSLGGNTHAWNNPWIVLLLVSAAALFVGFGLYEFYGATSPLISRTLIKNRNVMAVCLNNFFLSQSTMTMSYLIPQYFMGVLGYNPSSAGLWVFPRSILVAFGCYYSGRRLGVTGYYKHFVQTVMSCHVLIALGIYMWQPGQPLWYYLLCMNGEGFIFGLTFVATMVALVADIQHHETASATSMIFLFRSTGWLSGSTISAALMQSSFKSILYQSIQGPEAADLIEFVRSSITKIRTLAPEMQVIVLGALQKSIHTALLFAVVTSVLSWTFTFGLRNCQLKNVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N651</accession>
    <name>A0A1C7N651_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Zinc transporter 5</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">ZIP5_1</name>
        <name evidence="10" type="ORF">A0J61_07325</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 8">Membrane</location>
            <topology evidence="1 8">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the ZIP transporter (TC 2.A.5) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000487">
        <property type="protein sequence ID" value="OBZ84635.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N651"/>
    <dbReference type="FunCoup" id="A0A1C7N651">
        <property type="interactions" value="304"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N651"/>
    <dbReference type="InParanoid" id="A0A1C7N651"/>
    <dbReference type="OrthoDB" id="448280at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005385">
        <property type="term" value="F:zinc ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003689">
        <property type="entry name" value="ZIP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004698">
        <property type="entry name" value="Zn/Fe_permease_fun/pln"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00820">
        <property type="entry name" value="zip"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11040:SF44">
        <property type="entry name" value="PROTEIN ZNTC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11040">
        <property type="entry name" value="ZINC/IRON TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02535">
        <property type="entry name" value="Zip"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0406">Ion transport</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0732">Signal</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 8" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008889504" evidence="9">
        <location>
            <begin position="23"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="51"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="92"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="131"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="219"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="244"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="278"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="310"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="352"/>
            <end position="371"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006939"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU362088"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OBZ84635.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="372" mass="41160" checksum="202E581460891152" modified="2016-11-30" version="1">MTVNYKLLFTTIAVFFAAQVFAQDAPADETSTEEDACAAVPIQDYHLGLRIGSIFIILGTSAIGTYVPILLHRFSPYKRGAIRDWLLTIGKNDEHIGTGVILATAFVHMLPDALENFESPCLTDGWLSYEAFAGVFCMIASFALQLLEIVSVAHLNKMRRLKQERIDAENVNNEKASNSYKQTDASVTEEHDHHIGDSHGHTHGAFLEADEAYKHIGTYILELGIVMHSILIGIALSTTEFDEFISLLIALVFHQFFEGMALGTRLNEMNYTRWYKPVLMGLIYILMTPIGIIIGIGIRSYYNANSYSAVLASAILDSLSAGILLYNAYVSLMSMEISHSTAFHNSSTTRKVCCFISMYIGAGLMSLIGKWA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N737</accession>
    <name>A0A1C7N737_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_08817</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000716">
        <property type="protein sequence ID" value="OBZ83134.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N737"/>
    <dbReference type="InParanoid" id="A0A1C7N737"/>
    <dbReference type="OrthoDB" id="2285193at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="29"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="36"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ83134.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="365" mass="41262" checksum="C82FBC44FA68BF7E" modified="2016-11-30" version="1">MIEDTDSPTFAFFDFDFSELTDNNFDMPNGITPNITTDSSASVTSTSSTSSSSTVNHQQIVSSDSNAINIRKLEASRSSIGDTLLWSNIEELAKKMVYNNRNTLSCLDKFIREPNSDLVELVQCSDDDYFFFKNLVADSSNTPQTSTTAHYRDSNLASSKLIHKEKPPYAAYKYTDTALQQRKTNDSDRLNCFKKKLNTDSSCLYSQSGDSNTRQLTNALMRQTQRSTKKNDTVPQQNTLSSHQLSEANYLTSVAPYTYAATLTTLTKKQIAQCYQNQKASITMSSLRKGTAYHHPYYQRYGYSPGLGHSPNRAIQQKPTMYSSDLTKAQILEIQAISKAQQDFIRARERQEAEKSMMFKHHIKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N7G8</accession>
    <name>A0A1C7N7G8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_06957</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000445">
        <property type="protein sequence ID" value="OBZ84997.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N7G8"/>
    <dbReference type="InParanoid" id="A0A1C7N7G8"/>
    <dbReference type="OrthoDB" id="2289259at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ84997.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="456" mass="52259" checksum="20F7493D3AF7B5F4" modified="2016-11-30" version="1">MSSLKQTLDNYLRDNSNATLLDFVSSNITSFSSHMYNEKHSMKVKLQKTFTDVYKQHYPDRQVPSISLSNDLCANLFEYNKKTPADIRDKIFQWFYCLSESRHEEFADADKVTLEDFLRYNGSHPRVLLDKMAIMMLKDFERLKPNDIHVLKLAMSYIVDMMNENEEVYRRYIKQDFFWEIVGRCPVFLNNYVEEQEAAAITSLCKRTTEAIKKSLSAAMLFVLEEQAKLVKEDKTESSSYQVLQAFSFMLNNFKTWKKTQKESETQKVCRVYDLINIFFEDSTLNVKIGETLGRTTEEACFLNEHNFSGGSSSNYNSSGFSVSSVAAATALSSSSASCAGRKIDMTIVDDDKDELSYCEFKATNGKSLAQHQQSKSCRLNATIAHKMLKLFVDEHVVSFVWTGCFGEFCSLKEHEGVFVSRLVEPFVIPTQAVQLDEDIAKTFIMLIGWKVNKVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N832</accession>
    <name>A0A1C7N832_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Calcium-binding protein NCS-1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">ncs1</name>
        <name evidence="9" type="ORF">A0J61_06662</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the recoverin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000413">
        <property type="protein sequence ID" value="OBZ85285.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N832"/>
    <dbReference type="FunCoup" id="A0A1C7N832">
        <property type="interactions" value="116"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N832"/>
    <dbReference type="InParanoid" id="A0A1C7N832"/>
    <dbReference type="OrthoDB" id="191686at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00051">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.238.10:FF:000009">
        <property type="entry name" value="Visinin-like protein 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028846">
        <property type="entry name" value="Recoverin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23055">
        <property type="entry name" value="CALCIUM BINDING PROTEINS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23055:SF178">
        <property type="entry name" value="NEUROCALCIN HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00036">
        <property type="entry name" value="EF-hand_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13499">
        <property type="entry name" value="EF-hand_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00450">
        <property type="entry name" value="RECOVERIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00054">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0106">Calcium</keyword>
    <keyword evidence="6" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0519">Myristate</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="EF-hand" evidence="8">
        <location>
            <begin position="67"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="8">
        <location>
            <begin position="103"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="8">
        <location>
            <begin position="141"/>
            <end position="176"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00071944"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OBZ85285.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="187" mass="21557" checksum="5019A315EDF465A7" modified="2016-11-30" version="1">MGKAQSKLSPEQLTDLQKCTYCKEKLLIISMNYNNGGYKGFLKDCPSGQLDKTEFQKIYKQFFPFGDPSRFADYVFNVFDEDKNGMINFKEFIVALSVTSRGRLYDIDSDGYITREEMLQIVDAIYKMVGSMVKLPPDEDTPEKRVHKIFELMDTDKDGRLSMDEFREGSKKDPTILQALNLYDGMV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N8N7</accession>
    <name>A0A1C7N8N7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Stress response protein NST1</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">Stress response protein nst1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">nst1_0</name>
        <name evidence="8" type="ORF">A0J61_06496</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the NST1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000394">
        <property type="protein sequence ID" value="OBZ85451.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N8N7"/>
    <dbReference type="InParanoid" id="A0A1C7N8N7"/>
    <dbReference type="OrthoDB" id="21629at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025279">
        <property type="entry name" value="NST1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13945">
        <property type="entry name" value="NST1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="120"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="205"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="322"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="127"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="168"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="214"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="265"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="322"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="350"/>
            <end position="457"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00015112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00020733"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OBZ85451.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="457" mass="55922" checksum="496EC485964AE921" modified="2016-11-30" version="1">MRRTKCATVVKKGNITIIKRSERTSDVWTSTNYTEERQRIREFWLQLSEEERRSLVKVEKEAVLRKMKEQQKHSCNCSVCGKKRTAIEDELEVLYDAYYEELEQYAYRQQQQRKLIHHPYYQKNREEESDADEDDEDEDDDDEDDDDEEEEDDEEDEEQVSKHMHFESTPSFSNTLTVQGSVITVADDLLKNDGKKFLDMMEELAERKSRQEKEVEDNFLFSDEEEPNDCEESENDDEEDEEDDDDEEEEEDDDDDEEISDEEQVEIHKGKPNQDSRTEEQRMEEGRKMFQVFAARMFEQRVLNAYREKVAQDRQKRLIEELEEEDRLKQERELKKQQDKQKKRDKRRQLREQQEKERLELENKKRQEELAAKADREKKREESRLRKEQERQRKEEERLRKEEERKKKRLKAAEKERKRKEEEERKRKEEEELKRKQKQKEEQEPKQPSEKXLHMCV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N902</accession>
    <name>A0A1C7N902_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Transcriptional regulator prz1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">prz1_2</name>
        <name evidence="7" type="ORF">A0J61_06346</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000379">
        <property type="protein sequence ID" value="OBZ85605.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N902"/>
    <dbReference type="STRING" id="101091.A0A1C7N902"/>
    <dbReference type="InParanoid" id="A0A1C7N902"/>
    <dbReference type="OrthoDB" id="8922241at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005694">
        <property type="term" value="C:chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045893">
        <property type="term" value="P:positive regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000125">
        <property type="entry name" value="Putative zinc finger protein 143"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:001732">
        <property type="entry name" value="Zgc:162936"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23235">
        <property type="entry name" value="KRUEPPEL-LIKE TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23235:SF120">
        <property type="entry name" value="KRUPPEL-LIKE FACTOR 15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="6">
        <location>
            <begin position="156"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="6">
        <location>
            <begin position="186"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="6">
        <location>
            <begin position="214"/>
            <end position="243"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OBZ85605.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="276" mass="31768" checksum="B45FD3264E016151" modified="2016-11-30" version="1">MEYTYDFLPHQLSTGSSFTANTQAPILPVYVDSVLNHDSAAYYDNYTYQPKPNTLEQNMMSHLLQQSSYVYPVYNPYDYQPVKAEGEPIYCSIPVVDSLEENGLSQEPLMFDQTSNQRRHSLSSSMSSPSSCFSTLSSFTNPIEEKSTPRKSASLFRCTYEGCEKTFTRTYNLKSHLRTHTDQKPFVCCKCPKAFARQHDRNRHEKLHTGSKPYLCEHCNKSFARQDALNRHLKKDKRSISRRQNECLPLSPPCVSSKIRKTQLAMSKKKKSNYAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N9S1</accession>
    <name>A0A1C7N9S1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_06593</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000405">
        <property type="protein sequence ID" value="OBZ85356.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N9S1"/>
    <dbReference type="InParanoid" id="A0A1C7N9S1"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="121"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="31"/>
            <end position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ85356.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="155" mass="18062" checksum="FEDD5773D40B64D3" modified="2016-11-30" version="1">MAREADVKSLRVKESCSRRSSAHSAFRRISSRHDPINKRDKSDRRTKSTYSTREILGKAQRLGSKSSSKEDYTRLIESAKLTLVAVTVSSYKLEHKRKSIEGSLRLKRGPKDLLDEMSHRCDSFGRKLDELDSEYEDLRRLIWRLAKEKERMYGP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N9W4</accession>
    <name>A0A1C7N9W4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Cullin-associated NEDD8-dissociated protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">CAND1</name>
        <name evidence="8" type="ORF">A0J61_06077</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CAND family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000350">
        <property type="protein sequence ID" value="OBZ85871.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="FunCoup" id="A0A1C7N9W4">
        <property type="interactions" value="758"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N9W4"/>
    <dbReference type="InParanoid" id="A0A1C7N9W4"/>
    <dbReference type="OrthoDB" id="6260732at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010265">
        <property type="term" value="P:SCF complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039852">
        <property type="entry name" value="CAND1/CAND2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055406">
        <property type="entry name" value="HEAT_Maestro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021133">
        <property type="entry name" value="HEAT_type_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013932">
        <property type="entry name" value="TATA-bd_TIP120"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12696">
        <property type="entry name" value="TIP120"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23227">
        <property type="entry name" value="HEAT_MROH2B_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08623">
        <property type="entry name" value="TIP120"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25782">
        <property type="entry name" value="TPR_CAND1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50077">
        <property type="entry name" value="HEAT_REPEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="repeat" description="HEAT" evidence="4">
        <location>
            <begin position="51"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="domain" description="Maestro/Maestro-like HEAT-repeats" evidence="7">
        <location>
            <begin position="98"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="domain" description="TATA-binding protein interacting (TIP20)" evidence="6">
        <location>
            <begin position="1092"/>
            <end position="1249"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="315"/>
            <end position="348"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007657"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF08623"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF23227"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OBZ85871.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="1283" mass="143973" checksum="FB5FD9FE79A90C84" modified="2016-11-30" version="1">MAQGTNAYMVANLLEKMSNEDRDFRYMALNDLMNELQKDSFQMEFTIENKVVKAVLQLMDDKNGEVQNLAVKCLGPLVKQINETNLLEVIECLSQYASQQKNEELRGIAGIGIKTVVTEVDASKGHQMAQQVVPRLLSTIQKNDASYEMQMDTLDALSEVLSRFGHQVSTEQQIQIQSVLLPLLSYHRAAVRKRVTMAIGYLVVHTNDELFDQIYHSLYDSLTTDQKVKSEKTRTLVQCAGVLSRSSAVRLGNHLAQLVPVIMNYASKADGDDELREICLQTLESFLLRCPNEMTGFVQDIISLSLDYIKYDPNFVDDEDDDDEGQEDMDLEEDENEEEEDEFDDIADYSDDDDDMSWKVRRSASRVLCAIIESRPDLLQALYETVAPVLINRFKEREESVRVDILQSFIALLRQTGHYKDRRQFSSSLDNEIFSNPSLTPPIPTGPLQLLNAQVPKLCRAIVKQLSPKSTQTRQIGFQLLSEVILVLHGGLEEQIKSFIPAIESSLATTAIDQHHTSSSNLKIEVLYFLRLFLHHHPANTIHPYINSLAPAVIRSVSDKFYKITSEAFLVCIELIKVIRPVYRHDGQFEIAKIQPEFVQWIESIYQATVDILNTSDADQEVKERSIMCLGSLLAQVGDILSVQQPEAWDLLLERLRNEVTRLITVRTLTTVSQSPVAAGEALARCVLVAINDVSLLLRKSNRPLRIACLECLTILVNQFGKTMSAQQFHTILLELKPLMTDNDLHLLPLALKTVESILKASPSSVGDVKSLIIPELFKLIESPLLQGSALESLLNMFAAFVQARPSDYSLLVKDLVDPLLHVHTSGVSAGGVAAVANKQAASTVAQSVAVLTAHASPENRDRTIREFKSYLQQPSTNDSIKYLSLLAIGEMGRRIDLSQIENIEQEIIALFSAQSEEVKFAAAFALGNISVGNIHTYLPLILVQIKQEPKRRYLLLHALKEVITRYDTVNQDNSLQSASDEIWSLLLESSESDQEEGTRTVVAECLGKLALTNHAKFMPQLEERLSSSSAYVKATVATAIKYAVVDPSEDVDELLKPIMAQFLSLLQDNDLNVRRLALLTINSAAHRKPHLIRDIIPDLIPLLYAETVVKEELIHTVEMGPFKHKVDDGLEIRKAAFECMYTLLSTCLDKINVYDFLDRVCAGLDDQHDIKMLACLTLIRLSKVRPTAVTQKLDNLVTPFKTTLDFKMRSNAVKQEIEKNQELVRAVLRCIVALHPLSDPKTSPRFEHLELEVSTGPLSSEFKFAVSEAESRESRAVDSMEH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NA00</accession>
    <name>A0A1C7NA00_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_05986</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000342">
        <property type="protein sequence ID" value="OBZ85952.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NA00"/>
    <dbReference type="InParanoid" id="A0A1C7NA00"/>
    <dbReference type="OrthoDB" id="2272443at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="54"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ85952.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="98" mass="11135" checksum="9D2004A1E796673E" modified="2016-11-30" version="1">MSSFQYLIPKDPPSYESIYNTFPSSPPVSPPEQESCLSKASIAIKRFFRRHTPFLQTLIAAIFVAATVSTTVMLLLWQLQNLATPQDPDDPWLDLDEY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NB49</accession>
    <name>A0A1C7NB49_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Protein C12orf4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">CL004</name>
        <name evidence="3" type="ORF">A0J61_06085</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000351">
        <property type="protein sequence ID" value="OBZ85856.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NB49"/>
    <dbReference type="STRING" id="101091.A0A1C7NB49"/>
    <dbReference type="InParanoid" id="A0A1C7NB49"/>
    <dbReference type="OrthoDB" id="415359at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.10">
        <property type="entry name" value="DNA helicase RuvA subunit, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019311">
        <property type="entry name" value="Fy-3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015940">
        <property type="entry name" value="UBA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009060">
        <property type="entry name" value="UBA-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16525">
        <property type="entry name" value="PROTEIN C12ORF4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16525:SF0">
        <property type="entry name" value="PROTEIN C12ORF4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10154">
        <property type="entry name" value="Fy-3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22562">
        <property type="entry name" value="UBA_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00165">
        <property type="entry name" value="UBA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46934">
        <property type="entry name" value="UBA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50030">
        <property type="entry name" value="UBA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UBA" evidence="2">
        <location>
            <begin position="139"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="118"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="192"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="121"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="253"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50030"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ85856.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="624" mass="70612" checksum="6FE5164C5148C0FB" modified="2016-11-30" version="1" fragment="single">QAYEMESMSSPSSGTTSPRHSTHSTNSNMTTLFTRQVEEMEIFQATWQSDILQMRQTQRHQYREFVIELYHEYQARLASLSDEQQMLRLEDTLAMAEKKIDGKELVAAAASRIKQWDADSKTSSLRSESTGSKRSAEPSVNEVAVKSIEEMGFEREQAETALFLSNQSLEAAIGLLLENRERVDQFLIDQKAQRPPSVGSYRRSQSLSQVPRPALHSPQPTRTHSARQEPRRHSLLATSSSSSSIAPLHHKSNSSPNLLTNMPQQSSSAHLGKSWMNSFLHQQKQAMENTNLSSVRKLGGWLGKAMENLGMDHDSLLQKQQQYNAPQLVESFTILMGTAQIKSSHNLRLLVADEAEIFHPPYDPQREMAYRAETSTKLYTSHLSAAIVLVDLAELTRPQGWRQYKTGKGSNRALFERCQQSTEFHFADMETQLTCIQQDFEHHPDSLVEGTFFVTKHANLPSSQIIFHLVIDSTANAELTNRHALIRGLRHILKMTCQFDITSLSIPLLLLPEQSDYYPTSDPTIAWLQKRGEVVMKCIKGFLIENSRSGKRVQSEGSDRAESSMGGGGMRNIEFILPHRPEVYKTLVQTTNTVVNTHHMDIPPEVELAFQQFRTLLVNLFRTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NB61</accession>
    <name>A0A1C7NB61_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative methyltransferase C1B3.06c</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_05748</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000320">
        <property type="protein sequence ID" value="OBZ86198.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NB61"/>
    <dbReference type="FunCoup" id="A0A1C7NB61">
        <property type="interactions" value="432"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NB61"/>
    <dbReference type="InParanoid" id="A0A1C7NB61"/>
    <dbReference type="OrthoDB" id="2013972at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025714">
        <property type="entry name" value="Methyltranfer_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43591">
        <property type="entry name" value="METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43591:SF110">
        <property type="entry name" value="RHODANESE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13847">
        <property type="entry name" value="Methyltransf_31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransferase" evidence="2">
        <location>
            <begin position="111"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="59"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="20"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="66"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ86198.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="334" mass="38255" checksum="F936D531D6A3B7E1" modified="2016-11-30" version="1">MGTKLSTQSYIRARYRPSSKRPSTANSHSASHLDNFDNKKQISSSTSFDKFTRSQPLYRQVSTTHMDTDSRFGHSPRELDEDRMNATHFALKALFGANFLNTVQQTIDFDSKSTRVLDVGCGTGTWIMDMATEFPNTEFVGIDRVHIFPAAIRPPNATFKLVDVRDGLPFEDNTFDLVNTRLFLLDLTATLWPEFIKEVLRITKPGGILQMMELQIMDEGDEVVQEFCSKMEQMMLKEDLDPRICEKMGNLISKNGFIPKEEVAKAVPLKGHVLSDEFIYVLDIIFDIARLVAYNTYDLSSESEYQSVKKRYIQSRKQSTDVKWWWIAGQKPMA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NBB6</accession>
    <name>A0A1C7NBB6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">BAG domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_07324</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000487">
        <property type="protein sequence ID" value="OBZ84634.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NBB6"/>
    <dbReference type="STRING" id="101091.A0A1C7NBB6"/>
    <dbReference type="InParanoid" id="A0A1C7NBB6"/>
    <dbReference type="OrthoDB" id="333905at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051087">
        <property type="term" value="F:protein-folding chaperone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.120">
        <property type="entry name" value="BAG domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036533">
        <property type="entry name" value="BAG_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003103">
        <property type="entry name" value="BAG_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02179">
        <property type="entry name" value="BAG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63491">
        <property type="entry name" value="BAG domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51035">
        <property type="entry name" value="BAG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BAG" evidence="2">
        <location>
            <begin position="501"/>
            <end position="563"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="170"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="253"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="344"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="572"/>
            <end position="593"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="171"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="265"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="289"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="347"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="380"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="432"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="574"/>
            <end position="593"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ84634.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="593" mass="69463" checksum="5CF1A78D844E7E8E" modified="2016-11-30" version="1">MASPFLFGNKSLNLNDFLQLQALLDYEQQERDRHIAACQRKQDYYPPRHPNPSYAVPLFRQRAIDDVAARQSLAEKQRLEQAILKLKYLKDQYRRQRNAEIQSYLDAYRRQALIRAVQQEEEERYYRQCIAAALEQQRVNALWQQYLKAKQEEEYLRQKLEQEHILVAQQAEEEEKEEEDGESDEYFEEDEEDEGYSKYRTQQLEELLRHVFAHHPQYFEEDYNEKAPLHTSQTDSEDNHDLATDEIWKYLSDQKHDLESPRTALLSTGQKETSTPSDVKSKLVQGDGQEYEVEHESDESDAESERQDSSEATSSTSTPLPAVQDHVVSLQDLIQKLASEPVVVGQQAASEQLRDTQPSSFYSDEPKPSGIWINSQPPSENKKTKYHNEEKQEKDESYLPQHIFTEAEPTPTRETIPDVPFNMEEDSVIQVNKDEAKKTKEESDFVDSVAAEQKKQETNPQKAKQLESLNAIARELEDDSDLVKRWNQVLRSKLNFTKQPEGTLLVTASTDANRRYLGSEDEITRLMLKLDAVDSMGDEQIREKRRTLVKKCEHMVDVLDRMKHLQWQNAFKKLEKKKKNNRRRKSKKNKYKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NBE6</accession>
    <name>A0A1C7NBE6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 8">cAMP-dependent protein kinase regulatory subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">PKAR</name>
        <name evidence="12" type="ORF">A0J61_05520</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="8">Tetramer, composed of 2 regulatory (R) and 2 catalytic (C) subunits. In the presence of cAMP it dissociates into 2 active monomeric C subunits and an R dimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 8">Belongs to the cAMP-dependent kinase regulatory chain family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000300">
        <property type="protein sequence ID" value="OBZ86427.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NBE6"/>
    <dbReference type="FunCoup" id="A0A1C7NBE6">
        <property type="interactions" value="375"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NBE6"/>
    <dbReference type="InParanoid" id="A0A1C7NBE6"/>
    <dbReference type="OrthoDB" id="417078at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005952">
        <property type="term" value="C:cAMP-dependent protein kinase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030552">
        <property type="term" value="F:cAMP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004862">
        <property type="term" value="F:cAMP-dependent protein kinase inhibitor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034236">
        <property type="term" value="F:protein kinase A catalytic subunit binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033554">
        <property type="term" value="P:cellular response to stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd00038">
        <property type="entry name" value="CAP_ED"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="CDD" id="cd12098">
        <property type="entry name" value="DD_R_ScPKA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.120.10:FF:000039">
        <property type="entry name" value="cAMP-dependent protein kinase regulatory subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.120.10:FF:000006">
        <property type="entry name" value="cAMP-dependent protein kinase type I-alpha regulatory subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.890.10">
        <property type="entry name" value="cAMP-dependent protein kinase regulatory subunit, dimerization-anchoring domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="entry name" value="Jelly Rolls"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050503">
        <property type="entry name" value="cAMP-dep_PK_reg_su-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012198">
        <property type="entry name" value="cAMP_dep_PK_reg_su"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003117">
        <property type="entry name" value="cAMP_dep_PK_reg_su_I/II_a/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018488">
        <property type="entry name" value="cNMP-bd_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000595">
        <property type="entry name" value="cNMP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018490">
        <property type="entry name" value="cNMP-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11635">
        <property type="entry name" value="CAMP-DEPENDENT PROTEIN KINASE REGULATORY CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11635:SF152">
        <property type="entry name" value="CAMP-DEPENDENT PROTEIN KINASE TYPE I REGULATORY SUBUNIT-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00027">
        <property type="entry name" value="cNMP_binding"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02197">
        <property type="entry name" value="RIIa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000548">
        <property type="entry name" value="PK_regulatory"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00103">
        <property type="entry name" value="CAMPKINASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00100">
        <property type="entry name" value="cNMP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00394">
        <property type="entry name" value="RIIa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51206">
        <property type="entry name" value="cAMP-binding domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47391">
        <property type="entry name" value="Dimerization-anchoring domain of cAMP-dependent PK regulatory subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00888">
        <property type="entry name" value="CNMP_BINDING_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00889">
        <property type="entry name" value="CNMP_BINDING_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50042">
        <property type="entry name" value="CNMP_BINDING_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8 9" id="KW-0114">cAMP</keyword>
    <keyword evidence="4 8 9" id="KW-0116">cAMP-binding</keyword>
    <keyword evidence="12" id="KW-0418">Kinase</keyword>
    <keyword evidence="6 8 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="12" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Cyclic nucleotide-binding" evidence="11">
        <location>
            <begin position="170"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="domain" description="Cyclic nucleotide-binding" evidence="11">
        <location>
            <begin position="288"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="68"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="81"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="97"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="130"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="144"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="235"/>
        </location>
        <ligand>
            <name>3',5'-cyclic AMP</name>
            <dbReference type="ChEBI" id="CHEBI:58165"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="244"/>
        </location>
        <ligand>
            <name>3',5'-cyclic AMP</name>
            <dbReference type="ChEBI" id="CHEBI:58165"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="358"/>
        </location>
        <ligand>
            <name>3',5'-cyclic AMP</name>
            <dbReference type="ChEBI" id="CHEBI:58165"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="367"/>
        </location>
        <ligand>
            <name>3',5'-cyclic AMP</name>
            <dbReference type="ChEBI" id="CHEBI:58165"/>
            <label>2</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005753"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00020355"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022566"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRNR" id="PIRNR000548"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR000548-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="OBZ86427.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="417" mass="47548" checksum="3011B983898C501F" modified="2016-11-30" version="1">MSHSQEIHPFEQQKPQHYNNEEYTEVLNELNQQVVQHQPEDILQFCATFFLNKLEEERAKARQYDHHPLDPISHASLGPDFHPHGIDEDMHDRQNQDNDDDDEDDEERDTIAGEIPSISGPPPSSRGRRTSVSAESMQPSQHTQEFKKIVIPKSDEQRESIRAAIGNNFLFKNLDEEQYEDVVNAMAEKRISAQTLIIEQGAVGDYFYIVESGELDCFINGNKVTSYGPGGSFGELALMYNAPRAASIQAVTDCVLYALDRVTFRSILMENTARKRRMYERFLEEVPIFKSLEIYERHKIADALESIQYNDQEVVMREGDAGENFYLIESGEAIFYKSLPDGTQKQVMVGKKGDYFGELSLLNDEPRAATVIANGKLRCATLSKKAFIRLLGPVMDILKRNSENYHAVLQKDSQKML</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-06-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NCA9</accession>
    <name>A0A1C7NCA9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_05328</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000284">
        <property type="protein sequence ID" value="OBZ86620.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NCA9"/>
    <dbReference type="InParanoid" id="A0A1C7NCA9"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ86620.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="84" mass="9543" checksum="48E8A2D2D5C1F0D1" modified="2016-11-30" version="1">MPDYVIIDGHECLELSSVLERKLTDIAPIVVLQMSFSLVHRFEANRSAKLFHRFAKCSTCETTMNTPQKGISQSPIHICEHNEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2024-05-29" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NDP7</accession>
    <name>A0A1C7NDP7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_05052</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000262">
        <property type="protein sequence ID" value="OBZ86899.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NDP7"/>
    <dbReference type="InParanoid" id="A0A1C7NDP7"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ86899.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="70" mass="8132" checksum="CABF1A642D916EAF" modified="2016-11-30" version="1" fragment="single">ITRSSYSNLNIKTRPEYLGNFQLSADKSGYLKQHEQTNIPCLLLVFIIWSSFQQHQCNSLVVKPSFRDDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NDW7</accession>
    <name>A0A1C7NDW7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Calmodulin-4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">CAM4_0</name>
        <name evidence="4" type="ORF">A0J61_04669</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000233">
        <property type="protein sequence ID" value="OBZ87282.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NDW7"/>
    <dbReference type="STRING" id="101091.A0A1C7NDW7"/>
    <dbReference type="InParanoid" id="A0A1C7NDW7"/>
    <dbReference type="OrthoDB" id="26525at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00051">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.238.10:FF:000003">
        <property type="entry name" value="Calmodulin A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050145">
        <property type="entry name" value="Centrin_CML-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23050">
        <property type="entry name" value="CALCIUM BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13499">
        <property type="entry name" value="EF-hand_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13833">
        <property type="entry name" value="EF-hand_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00054">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0106">Calcium</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="EF-hand" evidence="3">
        <location>
            <begin position="43"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="3">
        <location>
            <begin position="79"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="3">
        <location>
            <begin position="115"/>
            <end position="150"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OBZ87282.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="155" mass="17016" checksum="8FCAF03BF97F51AE" modified="2016-11-30" version="1">MTGSTLTDAEINHLQAKFDSLTKGNGMTADTLKQIYQMAKIEVTDAEINEQIRAADAKGNGKVDFDDFMAVMNKQHETNAEEGVLRVFEMIDTDHDGQISNADLKRGISLFGKSVTDADIEDMMASADVDGDGLINYEEFLKIMTPSKVNGQSLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NEL5</accession>
    <name>A0A1C7NEL5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Medium-chain specific acyl-CoA dehydrogenase, mitochondrial</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">ACADM</name>
        <name evidence="11" type="ORF">A0J61_04956</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 7">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the acyl-CoA dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000254">
        <property type="protein sequence ID" value="OBZ86996.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NEL5"/>
    <dbReference type="STRING" id="101091.A0A1C7NEL5"/>
    <dbReference type="InParanoid" id="A0A1C7NEL5"/>
    <dbReference type="OrthoDB" id="9988775at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070991">
        <property type="term" value="F:medium-chain fatty acyl-CoA dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051793">
        <property type="term" value="P:medium-chain fatty acid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.110.10:FF:000001">
        <property type="entry name" value="Acyl-CoA dehydrogenase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.540.10:FF:000010">
        <property type="entry name" value="Medium-chain specific acyl-CoA dehydrogenase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.140.10:FF:000011">
        <property type="entry name" value="Medium-chain specific acyl-CoA dehydrogenase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.540.10">
        <property type="entry name" value="Acyl-CoA dehydrogenase/oxidase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.110.10">
        <property type="entry name" value="Butyryl-CoA Dehydrogenase, subunit A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.140.10">
        <property type="entry name" value="Butyryl-CoA Dehydrogenase, subunit A, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050741">
        <property type="entry name" value="Acyl-CoA_dehydrogenase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006089">
        <property type="entry name" value="Acyl-CoA_DH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006091">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046373">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036250">
        <property type="entry name" value="AcylCo_DH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009075">
        <property type="entry name" value="AcylCo_DH/oxidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013786">
        <property type="entry name" value="AcylCoA_DH/ox_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037069">
        <property type="entry name" value="AcylCoA_DH/ox_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009100">
        <property type="entry name" value="AcylCoA_DH/oxidase_NM_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48083:SF2">
        <property type="entry name" value="MEDIUM-CHAIN SPECIFIC ACYL-COA DEHYDROGENASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48083">
        <property type="entry name" value="MEDIUM-CHAIN SPECIFIC ACYL-COA DEHYDROGENASE, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00441">
        <property type="entry name" value="Acyl-CoA_dh_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02770">
        <property type="entry name" value="Acyl-CoA_dh_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02771">
        <property type="entry name" value="Acyl-CoA_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016578">
        <property type="entry name" value="HsaA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47203">
        <property type="entry name" value="Acyl-CoA dehydrogenase C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56645">
        <property type="entry name" value="Acyl-CoA dehydrogenase NM domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00072">
        <property type="entry name" value="ACYL_COA_DH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00073">
        <property type="entry name" value="ACYL_COA_DH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0274">FAD</keyword>
    <keyword evidence="4 7" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="6 7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Acyl-CoA dehydrogenase/oxidase N-terminal" evidence="10">
        <location>
            <begin position="30"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA oxidase/dehydrogenase middle" evidence="9">
        <location>
            <begin position="146"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA dehydrogenase/oxidase C-terminal" evidence="8">
        <location>
            <begin position="254"/>
            <end position="402"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00019125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU362125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF02770"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF02771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="OBZ86996.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="416" mass="44882" checksum="BD008AD0A69017B0" modified="2016-11-30" version="1">MLRSVQKLVRPYNRHYSTESLSLGMSFSFTEEQKSIQGMARKFTREEIIPVAAEHDQTGKYPVDIIKKAWELGLVNTHIDSKYGGMNLGVLDSAIISEELAYGCSGIQTAIEANNLAEAPLVVAGSEEQKKKYLGRMTEAPLMASYGVTEPGAGSDVASLSTTAVKKSDGSWVLNGQKMWITNAGHANWFFVLAKTDANANAGKAFTGFVVDADTPGITLGRKEINMGQRASDTRGVTFEDVVVPAENVLGTEGQGFKIAMNAFDITRPLVASAAVGLARRAMEEATKYALERKTMGKTIASHQAVAFMLADMAIGVESARMMVYRSAFMRDQGEKNTFYASIAKALAGDVANKCASDAVQIFGGNGFNTEYPVEKLMRDAKIFQIYEGTAQVQRLIISRLLLDSAKSGADALGGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NES4</accession>
    <name>A0A1C7NES4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Exosome complex protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">C1d_1</name>
        <name evidence="8" type="ORF">A0J61_06115</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Required for exosome-dependent processing of pre-rRNA and small nucleolar RNA (snRNA) precursors. Involved in processing of 35S pre-rRNA at the A0, A1 and A2 sites.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the C1D family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000354">
        <property type="protein sequence ID" value="OBZ85834.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NES4"/>
    <dbReference type="STRING" id="101091.A0A1C7NES4"/>
    <dbReference type="InParanoid" id="A0A1C7NES4"/>
    <dbReference type="OrthoDB" id="10261072at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000178">
        <property type="term" value="C:exosome (RNase complex)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000460">
        <property type="term" value="P:maturation of 5.8S rRNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010468">
        <property type="term" value="P:regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011082">
        <property type="entry name" value="Exosome-assoc_fac/DNA_repair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007146">
        <property type="entry name" value="Sas10/Utp3/C1D"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15341:SF3">
        <property type="entry name" value="NUCLEAR NUCLEIC ACID-BINDING PROTEIN C1D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15341">
        <property type="entry name" value="SUN-COR STEROID HORMONE RECEPTOR CO-REPRESSOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04000">
        <property type="entry name" value="Sas10_Utp3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3 6" id="KW-0698">rRNA processing</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="20"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="127"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="346"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009154"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU368003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OBZ85834.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="346" mass="40030" checksum="FE086D3328FFB152" modified="2016-11-30" version="1" fragment="single">MSMDDKWEFDMPKFWDFTNSIPQQRPNESWFCEKNISGPSFPVQDKPKQTQPTKCSKLSVFDRLARENTVASTSKLNHKQPTDKVQPPRLKKTLSDHTSSFQPRPPHTRKRLREGNKPVESIPSTNGDRKEDAHLDSTNKRFKTKPKLIEITTAGLEQVKARPRKLLKGTVNYSHSNVVSDEDFSLKCTMNEEERRRLPEITIARAILAREDLRQIPKKAVRALRSRLQVVKKHLDPLLARPINDVFSKLSLNERYELEVLLSYSLNTLFYIYMRTQGTDPQKHVVMKELARVQQYIQKLKKAVGKEEKPNMKVDKEAASRFIKAALTEENSTKRKLEDTESSSSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NF44</accession>
    <name>A0A1C7NF44_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_04371</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000212">
        <property type="protein sequence ID" value="OBZ87590.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NF44"/>
    <dbReference type="InParanoid" id="A0A1C7NF44"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="SMART" id="SM00256">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="1">
        <location>
            <begin position="1"/>
            <end position="44"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ87590.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="560" mass="64655" checksum="ED93D4C143204C67" modified="2016-11-30" version="1">MIHLLPIEMADCISLYLSTRDIFQLSIVNHAFRTMFTASLYKTIKFCNLKDFENFLSIPSRPFQYVRQLDLWFNMNKENQLQNLSSLLPLLDSFALNISDSPKLFEQVYPSLQHLTTLHLEISYDYDEEVNHDDELIHFIICLLKTTPNLTVLSVFLSTQQLSVYLLDCINFECPLIEHLSVVADTVRTPDTMSMAVHHFPHLKSFELSALFSLPVHPGWLRYVGDRYPNIERLKLGANDVSIGSIFSPELYDRFFSSCPRLVYFDWHNILPDSFFLQRLSQSQRQAQYITLSRPDYIMDHLLGASSSRTAYFSNIMNLDIYLPEEMACDTFFSSLANACPQLQQIKVKSFCYYPVNQISIGTLLDSFPCVTLLQLEGIQLCHSNHNLPVSHPLRNLTLKHSGLSDKEINALVIRCPDLERMTLSEINHEEEGSLMVHLPYLTFTLLDLSRIFMRHDVIYAVNQLFYVEQQKASGWYRLSSKQITKVSKEQLISACRELDTDEKERLKTISPRIYALLDGSLCTLESNSHLVEAIKMGYIEIVCPFIRSIYIQDNKISNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NF49</accession>
    <name>A0A1C7NF49_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Arrestin domain-containing protein C31A2.12</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_05988</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000342">
        <property type="protein sequence ID" value="OBZ85954.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NF49"/>
    <dbReference type="STRING" id="101091.A0A1C7NF49"/>
    <dbReference type="InParanoid" id="A0A1C7NF49"/>
    <dbReference type="OrthoDB" id="2333384at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.640">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014752">
        <property type="entry name" value="Arrestin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011021">
        <property type="entry name" value="Arrestin-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050357">
        <property type="entry name" value="Arrestin_domain-protein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11188">
        <property type="entry name" value="ARRESTIN DOMAIN CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11188:SF17">
        <property type="entry name" value="FI21816P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00339">
        <property type="entry name" value="Arrestin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="E set domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Arrestin-like N-terminal" evidence="2">
        <location>
            <begin position="36"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="306"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="479"/>
            <end position="511"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="310"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="335"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="488"/>
            <end position="497"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ85954.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="531" mass="59857" checksum="0B2060B31F3CE474" modified="2016-11-30" version="1">MPHLKTSHKEDATITLSLDPSFTGVIRGIAHDESEGCTVKGNCIVQVNKPIKIRRFVVWLEGRCKVTLKAGSYGYTVANTETNESRTIYSKDHHFIGDDGLTHLLTPGHYLYPFSFELPPSLPASFRGKRGYVRYRLQAAIYRPMFAHDIHVSRDIPIKRCLLNDETPMAELRETYEGRQHTNKIHYEATAPSITYREGGLIRLNINMRLLKPEHQSVRTVTCALRERVQYRTTDGQANTICSKTDNLFPLGYSTFYPSQSPDYDPKEQADYNALFRLCPRVNADLNSRLMKVTHALVVNIMMEDRSDEKEEDESAFETDATDTEWASEDDHQNTVHSFQSISSDTKQTHESPNTTPPASAPSSPILSRSSSASSLVSIFSLARSHPSSPNPSHGDDYLAAGMTSIPAVKSARRKHRHKDTHEPRLILCTLEVPLVVTSREHTWNDKPSHHLSDTTPPSYDTVEKPPTYHMAIENLPRAPIYDRDDPSPCPSEPSTPPNEEIHRPSLTQHHRHSFTDLAARVFSKAGMTHS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NF70</accession>
    <name>A0A1C7NF70_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_04260</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000204">
        <property type="protein sequence ID" value="OBZ87698.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NF70"/>
    <dbReference type="InParanoid" id="A0A1C7NF70"/>
    <dbReference type="OrthoDB" id="2403564at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ87698.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="172" mass="19593" checksum="25FD963C93B1BACB" modified="2016-11-30" version="1">MSSTTDIQRKRSLSMESDQEPKKKRPRESGQLLDDLTQILAQIRSTPSTGEISADLLSSFRILMLQIESMSSDRSNIEAKDMRDQTDRYLDAWFQELIVECFSENEDGLIDGLEEENDLAGPQTNEDEDDDIALALALQDEEEYCKDISREEICSKVRGGHDENEDVEIEIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NFU0</accession>
    <name>A0A1C7NFU0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Transmembrane protein UsgS</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_04080</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000191">
        <property type="protein sequence ID" value="OBZ87888.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NFU0"/>
    <dbReference type="InParanoid" id="A0A1C7NFU0"/>
    <dbReference type="OrthoDB" id="10041630at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38421:SF1">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38421">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN USGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="37"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="87"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="160"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="191"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="255"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="296"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="304"/>
            <end position="316"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ87888.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="316" mass="36019" checksum="0F60F33FE62749DF" modified="2016-11-30" version="1">MVRWTLAGLKKGAIYAVEGILIVLKNPNMRKQRFLKVFIYLCTVSFVLFILTKLLIVIPLQIVKGILWLTSDKASHADQALERANRLIHEVVAYLPLCALLFMQYVYPKPLDDLFMESLRYLDEKNPQRPPYASVLAQKKFEKHFWRDMHAYLIRSWKKLRIGFVLLLLSTIPRVGQFVFPTAGAYTSYRALGRTQAVAVGICFFFLPQRATMELVRALIGMRSLMRELLAPYFIRMNMTHKEKLRWFSGRKDVLFGFSAIAYLMIRIPIVGAVAYGVAQAASAYMLTVVTEPPTLESASQQPTEDKASAEKGASK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NFW4</accession>
    <name>A0A1C7NFW4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">ATPase inhibitor, mitochondrial</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">A0J61_03908</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Inhibits the enzyme activity of ATPase.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 4">Belongs to the ATPase inhibitor family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000179">
        <property type="protein sequence ID" value="OBZ88041.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NFW4"/>
    <dbReference type="InParanoid" id="A0A1C7NFW4"/>
    <dbReference type="OrthoDB" id="5532350at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042030">
        <property type="term" value="F:ATPase inhibitor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.500">
        <property type="entry name" value="Single helix bin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007648">
        <property type="entry name" value="ATPase_inhibitor_mt"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04568">
        <property type="entry name" value="IATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64602">
        <property type="entry name" value="F1 ATPase inhibitor, IF1, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="22"/>
            <end position="49"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010901"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU368087"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OBZ88041.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="49" mass="5556" checksum="22D0DEF170398BA4" modified="2016-11-30" version="1">MNPSDSKLFASREKAAEDQYIRQKEAEQLKALKASMEAAKKDDKATQKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-06-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NG40</accession>
    <name>A0A1C7NG40_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_03888</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000178">
        <property type="protein sequence ID" value="OBZ88062.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NG40"/>
    <dbReference type="InParanoid" id="A0A1C7NG40"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ88062.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="122" mass="13851" checksum="980217C8ECF9FCB1" modified="2016-11-30" version="1">MNQAVYNSQDEKQKITANRCQVRIDAYEGILKNKSAPISKTKLEQQKKPRLINDDDNELLDLMNLNKELSAAEDRILELEDNATKNNIASPPLFKTRIKVLEAILRAALYSNPQKGTTLQIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NG79</accession>
    <name>A0A1C7NG79_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_03862</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000175">
        <property type="protein sequence ID" value="OBZ88107.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NG79"/>
    <dbReference type="STRING" id="101091.A0A1C7NG79"/>
    <dbReference type="InParanoid" id="A0A1C7NG79"/>
    <dbReference type="OrthoDB" id="5430106at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031931">
        <property type="term" value="C:TORC1 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031929">
        <property type="term" value="P:TOR signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018857">
        <property type="entry name" value="TORC1_cplx_su_TCO89"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10452">
        <property type="entry name" value="TCO89"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="246"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="35"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="60"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="72"/>
            <end position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ88107.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="316" mass="35712" checksum="624934CC2AD24753" modified="2016-11-30" version="1">MTGQEDQSKKSKKFAVGDLPPSPTTSTGMIGNAKRPTRHHVKRRSSGRVHVSKLAPMARAHAEADSEKPIKRSQSNKSLSRLSTLERSKSTSMISLTPALDDTAPDPHSPPTTPPMKGKETDTIKPTFHVSNTMPAAPVEHTLPVTADDLVTDKKKTFLKSQFVDKKTTLSNAASSGMTRTQQKLLLQREQSLIHDENHIAHPKNMIRLTREMEKMGKEYRCVRKYQDPMMDSLIRCHEKQQQQKMPHKLHQRTHSSTQLSAPVPHMEQRRQILLKTALQKQQQEQEQHDESSLSLLDGNRWSAGNLLERLFYGVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NH17</accession>
    <name>A0A1C7NH17_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">MIT domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">A0J61_03900</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000179">
        <property type="protein sequence ID" value="OBZ88049.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NH17"/>
    <dbReference type="STRING" id="101091.A0A1C7NH17"/>
    <dbReference type="InParanoid" id="A0A1C7NH17"/>
    <dbReference type="OrthoDB" id="2245455at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.80">
        <property type="entry name" value="Phosphotransferase system, lactose/cellobiose-type IIA subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007330">
        <property type="entry name" value="MIT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036181">
        <property type="entry name" value="MIT_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37327">
        <property type="entry name" value="CHROMOSOME 1, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37327:SF1">
        <property type="entry name" value="MICROTUBULE INTERACTING AND TRANSPORT DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04212">
        <property type="entry name" value="MIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF116846">
        <property type="entry name" value="MIT domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MIT" evidence="3">
        <location>
            <begin position="38"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="200"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="446"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="15"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="200"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="235"/>
            <end position="259"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF04212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OBZ88049.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="627" mass="70176" checksum="C5F32D39AFF224B2" modified="2016-11-30" version="1">MSLDTSVKPAMLRESTYSTHPQPSSSSEDQKQMSKLILKTALQKANVAVQCDSKNDIIGAIDAYQEAIDLLEQVLVTVDKPNDRLRLQEIYDSYSERVQLLTSITQKITAINHTDYEEPDSPIITNSNNLWQDNNQLSSAITRTRLVSEKELTNIPVSLPNTPQSQTFGKYVNGQTTPVSSNFHDASTKLRSCSISSADSEFSDENSTCEQPSMALPSLRKKEDKTSKSKPTCRARTTSLPKHSLGMQRSSSISTVESAGSYASPSIDYSIEEEEEEYKMTIDKQSAEQGSKHPISINTSQPAIASRPFVVDLGSLRRRATNRVSADTSVERSNSIKTVDSPASASTFSFFMKDSYHQGDEISSYHSNQRGSVDSCEPDGDYLSLLLILEKSMIEGAHMTHRLYIPKNLWLQPSIKLPSMDIKVSACETISNEITRLEKWSHLDDLKSSIKILEQLENSVDQLQITLAKKLKSESLNSEVPSSPLYSGSSAASSQASVYSLQSQSSTTTVNRTESTKKGQSFMSWGNKLTKSVERMNAFSLTKPEYQFKHYTEALQKLFTKIHVLERWLMHYTLEKRKSRQPQHDILISKLIRICTNTNNLVGGFVVRDITILLEKWLKRGGSWVSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NH97</accession>
    <name>A0A1C7NH97_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Small ribosomal subunit protein uS19m</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">RSM19</name>
        <name evidence="6" type="ORF">A0J61_03544</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the universal ribosomal protein uS19 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000154">
        <property type="protein sequence ID" value="OBZ88405.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NH97"/>
    <dbReference type="FunCoup" id="A0A1C7NH97">
        <property type="interactions" value="43"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NH97"/>
    <dbReference type="InParanoid" id="A0A1C7NH97"/>
    <dbReference type="OrthoDB" id="2043at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005763">
        <property type="term" value="C:mitochondrial small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000028">
        <property type="term" value="P:ribosomal small subunit assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.860.10:FF:000001">
        <property type="entry name" value="30S ribosomal protein S19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.860.10">
        <property type="entry name" value="30s Ribosomal Protein S19, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00531">
        <property type="entry name" value="Ribosomal_uS19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002222">
        <property type="entry name" value="Ribosomal_uS19"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020934">
        <property type="entry name" value="Ribosomal_uS19_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023575">
        <property type="entry name" value="Ribosomal_uS19_SF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11880">
        <property type="entry name" value="RIBOSOMAL PROTEIN S19P FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11880:SF8">
        <property type="entry name" value="SMALL RIBOSOMAL SUBUNIT PROTEIN US19M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00203">
        <property type="entry name" value="Ribosomal_S19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002144">
        <property type="entry name" value="Ribosomal_S19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00975">
        <property type="entry name" value="RIBOSOMALS19"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54570">
        <property type="entry name" value="Ribosomal protein S19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00323">
        <property type="entry name" value="RIBOSOMAL_S19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 5 6" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00044183"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OBZ88405.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="85" mass="9572" checksum="6602FB68F200A679" modified="2016-11-30" version="1">MPRSAWKGPFFVAFPGLKQAIQAGTPIATQARSCTILPSFVGLKFLVHNGKDYLPVHVTEEMIGHKLGEFAFTRKRFSYRFTKAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NHC5</accession>
    <name>A0A1C7NHC5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_03992</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000186">
        <property type="protein sequence ID" value="OBZ87946.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NHC5"/>
    <dbReference type="InParanoid" id="A0A1C7NHC5"/>
    <dbReference type="OrthoDB" id="2290280at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ87946.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="71" mass="8313" checksum="8F73D1776660B3D7" modified="2016-11-30" version="1">MGYPRQVGRRKAAADQRLLSRLQGKRNKLMRDYELTSILPPKLETIENQLGAIQQDRVDTLALRAIKHWRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NHI3</accession>
    <name>A0A1C7NHI3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="10">High-affinity glucose transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">HGT1_4</name>
        <name evidence="10" type="ORF">A0J61_03498</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000152">
        <property type="protein sequence ID" value="OBZ88450.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NHI3"/>
    <dbReference type="FunCoup" id="A0A1C7NHI3">
        <property type="interactions" value="330"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NHI3"/>
    <dbReference type="InParanoid" id="A0A1C7NHI3"/>
    <dbReference type="OrthoDB" id="4142200at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005351">
        <property type="term" value="F:carbohydrate:proton symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd17356">
        <property type="entry name" value="MFS_HXT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000026">
        <property type="entry name" value="MFS quinate transporter QutD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050360">
        <property type="entry name" value="MFS_Sugar_Transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00879">
        <property type="entry name" value="SP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022:SF2">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00171">
        <property type="entry name" value="SUGRTRNSPORT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00216">
        <property type="entry name" value="SUGAR_TRANSPORT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00217">
        <property type="entry name" value="SUGAR_TRANSPORT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0762">Sugar transport</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="7"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="53"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="83"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="111"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="140"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="171"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="260"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="294"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="331"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="370"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="417"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="442"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="9">
        <location>
            <begin position="10"/>
            <end position="463"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OBZ88450.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="502" mass="54049" checksum="5AF32EDD4E779DA5" modified="2016-11-30" version="1">MGNNFLLYGVCAFAAIGGFLFGYDTGVISSILTMNRFQIKMAGVESLTSLQEGTITGLLLAGCFVGSLLAAPSAERFSRKITIIIGTGVFMVGAALQCGADGYAMMVVGRAVAGLGIGCISMIVPLYQSELAPKEIRGRLIALQQLMCTAGIMVAFWVGVGTDPLDSDAQWRIPLGVQIAPAIVLFFGAMFLPYSPRWLVSKGRNAEALEVLARLHGNGDQTDPRVVGEYEDIVAQIELERSVAVGSYAELLKPKLRRRLVLGVLTQIFQQFTGINSIMYYAPTIFSQAGIGAHSATLIASGVNGVLNMFATIPAVLYVDRFGRRKILISGALFMATAMLLCGIVMAATGKVTFDEATGKHGVDMSGNINASYFCIVMIYFFVAGFAYSWGPVGWIYPAEIYPLSVRAKGTSITTSANWLFNFVISEICPAMLASITWGTYIFFGCCCIIMSVVVYIFFPETKGKSLEEMDMVFGGSIFAFKNQANISEEITVASDEKKGSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NHI5</accession>
    <name>A0A1C7NHI5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_03388</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000144">
        <property type="protein sequence ID" value="OBZ88567.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NHI5"/>
    <dbReference type="InParanoid" id="A0A1C7NHI5"/>
    <dbReference type="OrthoDB" id="1845550at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="6"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="43"/>
            <end position="69"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ88567.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="69" mass="7852" checksum="B2BAA73D6F5765D5" modified="2016-11-30" version="1">MSAVTKFYAQVFGIGAALGAGMEVMLIKSNYYQMLAASEAKQRMKELQQEQEDNERFNRIKSQSQEKEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NI22</accession>
    <name>A0A1C7NI22_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Transcriptional activator Myb</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">myb_0</name>
        <name evidence="8" type="ORF">A0J61_03164</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000132">
        <property type="protein sequence ID" value="OBZ88783.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NI22"/>
    <dbReference type="STRING" id="101091.A0A1C7NI22"/>
    <dbReference type="InParanoid" id="A0A1C7NI22"/>
    <dbReference type="OrthoDB" id="2143914at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019185">
        <property type="term" value="C:snRNA-activating protein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001006">
        <property type="term" value="F:RNA polymerase III type 3 promoter sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042795">
        <property type="term" value="P:snRNA transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042796">
        <property type="term" value="P:snRNA transcription by RNA polymerase III"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00167">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.60:FF:000016">
        <property type="entry name" value="Transcriptional activator Myb isoform A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051575">
        <property type="entry name" value="Myb-like_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017930">
        <property type="entry name" value="Myb_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001005">
        <property type="entry name" value="SANT/Myb"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46621">
        <property type="entry name" value="SNRNA-ACTIVATING PROTEIN COMPLEX SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46621:SF1">
        <property type="entry name" value="SNRNA-ACTIVATING PROTEIN COMPLEX SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13921">
        <property type="entry name" value="Myb_DNA-bind_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00249">
        <property type="entry name" value="Myb_DNA-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00717">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51294">
        <property type="entry name" value="HTH_MYB"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50090">
        <property type="entry name" value="MYB_LIKE"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Myb-like" evidence="6">
        <location>
            <begin position="102"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="domain" description="HTH myb-type" evidence="7">
        <location>
            <begin position="109"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="domain" description="Myb-like" evidence="6">
        <location>
            <begin position="154"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="domain" description="HTH myb-type" evidence="7">
        <location>
            <begin position="216"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="domain" description="Myb-like" evidence="6">
        <location>
            <begin position="216"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="269"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="269"/>
            <end position="288"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OBZ88783.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="435" mass="50028" checksum="9720F034B1C1C403" modified="2016-11-30" version="1">MNIHHQQEPLQQLQQHQVMAGLVQPQPILKVEGVIQTPTLSDYDPHYGGLSSSCTSPYMMSPIGSKRRFSLGGYDGPRWTPYTPFMSPIVTTTRSHSVKRNKRPSTYSRWTTEEDELLKQAVQLHGPHKWSLIASHVPNRTPMQCSTRWLGALNPNIHKGRWTENEDAILRYSVLEYANVTDSEGRLQPIPWNKIAERIPNRTGIQCQARWTEALDPYVRKGKWGVEEDALLRMGVNDFGRCWIRIAETIPGRTQRQCRTRWMQIKYKEDRQQKQEQKRGSLDGKSSDIIDDISSQSYVSSDDEEEEEVNATASSTATAAAAAALLERQQQYQQQYQQQYQQQYQQQQLQQLQQLPQAQAQQQAICDPSFFIVDGFENQLQHSHCFTRPLMETATTNNLSTASTNGASDFLKEDGFFLPQDWSLHDYQQQNTTYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-06-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NI90</accession>
    <name>A0A1C7NI90_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_03707</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000165">
        <property type="protein sequence ID" value="OBZ88236.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NI90"/>
    <dbReference type="InParanoid" id="A0A1C7NI90"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ88236.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="62" mass="7318" checksum="08FA06F431E462F5" modified="2016-11-30" version="1">MANTTYYGDKYKNRVDRESYPGCFDHNKKSRLLPYLGMPITYFLSYLSKCCHSGSQKQQQKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NIL8</accession>
    <name>A0A1C7NIL8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Succinate dehydrogenase assembly factor 3</fullName>
            <shortName evidence="6">SDH assembly factor 3</shortName>
            <shortName evidence="6">SDHAF3</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">A0J61_03296</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Plays an essential role in the assembly of succinate dehydrogenase (SDH), an enzyme complex (also referred to as respiratory complex II) that is a component of both the tricarboxylic acid (TCA) cycle and the mitochondrial electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Promotes maturation of the iron-sulfur protein subunit of the SDH catalytic dimer, protecting it from the deleterious effects of oxidants. May act together with SDHAF1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Interacts with the iron-sulfur protein subunit within the SDH catalytic dimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Mitochondrion matrix</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the complex I LYR family. SDHAF3 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000139">
        <property type="protein sequence ID" value="OBZ88649.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NIL8"/>
    <dbReference type="FunCoup" id="A0A1C7NIL8">
        <property type="interactions" value="74"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NIL8"/>
    <dbReference type="InParanoid" id="A0A1C7NIL8"/>
    <dbReference type="OrthoDB" id="278329at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005758">
        <property type="term" value="C:mitochondrial intermembrane space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015976">
        <property type="term" value="P:carbon utilization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034553">
        <property type="term" value="P:mitochondrial respiratory chain complex II assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006111">
        <property type="term" value="P:regulation of gluconeogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006105">
        <property type="term" value="P:succinate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd20270">
        <property type="entry name" value="Complex1_LYR_SDHAF3_LYRM10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008381">
        <property type="entry name" value="SDHAF3/Sdh7"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13137">
        <property type="entry name" value="DC11 ACN9 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13137:SF6">
        <property type="entry name" value="SUCCINATE DEHYDROGENASE ASSEMBLY FACTOR 3, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13233">
        <property type="entry name" value="Complex1_LYR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0143">Chaperone</keyword>
    <keyword evidence="4 6" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0809">Transit peptide</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="74"/>
            <end position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004305"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU368039"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OBZ88649.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="134" mass="15157" checksum="232C63DEBA7C4524" modified="2016-11-30" version="1">MPGPQQTQVLMAPLKLYRDILRSHRALPAAMRSMGDDYVKSEFKRHKTIDNPAHIVGFVSQWQSYLDLIKEQTAPLPKDSPAPSDDPLVRSFNIPANGGWGKKLDPQLLDKMSDEQLGQLYELRSEVKRSLGDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NIR5</accession>
    <name>A0A1C7NIR5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Golgi apparatus membrane protein tvp15</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">A0J61_03042</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000124">
        <property type="protein sequence ID" value="OBZ88915.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NIR5"/>
    <dbReference type="STRING" id="101091.A0A1C7NIR5"/>
    <dbReference type="InParanoid" id="A0A1C7NIR5"/>
    <dbReference type="OrthoDB" id="423534at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013714">
        <property type="entry name" value="Golgi_TVP15"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28128">
        <property type="entry name" value="GOLGI APPARATUS MEMBRANE PROTEIN TVP15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28128:SF1">
        <property type="entry name" value="GOLGI APPARATUS MEMBRANE PROTEIN TVP15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08507">
        <property type="entry name" value="COPI_assoc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="20"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="46"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OBZ88915.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="202" mass="23093" checksum="997B87068988006C" modified="2016-11-30" version="1">MAKENPTMISRTKVENILCLTFNAINIILYAFVIVAIIFKCIQGNFADIVMGIYGIIIAILMIVNELQEFEFSYHYFYFLSTYRGRGFLMMFFGCLVLDSGIVNIVVGTLTLATGLLYIILSFTSNFPPPNPITINWRNWVDFSAEGLDLPHHRTANDTVVSEMHERLKSPAPIVQNHAVSLNDMIDPEKQPMMKNQHNRRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NIW3</accession>
    <name>A0A1C7NIW3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_02966</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000120">
        <property type="protein sequence ID" value="OBZ88975.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NIW3"/>
    <dbReference type="InParanoid" id="A0A1C7NIW3"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008889719" evidence="1">
        <location>
            <begin position="21"/>
            <end position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ88975.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="125" mass="13960" checksum="8C0EDC8010A9E517" modified="2016-11-30" version="1">MKSFALFVLAALTILSIVCADTWSLDMQCLVEAQIILRHSNELGSQSIVWSQGQLDNGNELCSSDQVICVKDIIVKKENCQEVTIDFKVQYASKWSNNITAVLHGIWSSAGYLSRVYKFAPVFEP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NJ33</accession>
    <name>A0A1C7NJ33_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Chondroitinase-AC</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">cslA_1</name>
        <name evidence="7" type="ORF">A0J61_04625</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the polysaccharide lyase 8 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000230">
        <property type="protein sequence ID" value="OBZ87324.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NJ33"/>
    <dbReference type="InParanoid" id="A0A1C7NJ33"/>
    <dbReference type="OrthoDB" id="5980780at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016837">
        <property type="term" value="F:carbon-oxygen lyase activity, acting on polysaccharides"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.98.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.100">
        <property type="entry name" value="Chondroitin AC/alginate lyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.220.10">
        <property type="entry name" value="Polysaccharide lyase family 8-like, C-terminal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008929">
        <property type="entry name" value="Chondroitin_lyas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011013">
        <property type="entry name" value="Gal_mutarotase_sf_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014718">
        <property type="entry name" value="GH-type_carb-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038970">
        <property type="entry name" value="Lyase_8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011071">
        <property type="entry name" value="Lyase_8-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012970">
        <property type="entry name" value="Lyase_8_alpha_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004103">
        <property type="entry name" value="Lyase_8_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003159">
        <property type="entry name" value="Lyase_8_central_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38481">
        <property type="entry name" value="HYALURONATE LYASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38481:SF1">
        <property type="entry name" value="HYALURONATE LYASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02278">
        <property type="entry name" value="Lyase_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02884">
        <property type="entry name" value="Lyase_8_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08124">
        <property type="entry name" value="Lyase_8_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48230">
        <property type="entry name" value="Chondroitin AC/alginate lyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74650">
        <property type="entry name" value="Galactose mutarotase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49863">
        <property type="entry name" value="Hyaluronate lyase-like, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0456">Lyase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="domain" description="Polysaccharide lyase 8 N-terminal alpha-helical" evidence="6">
        <location>
            <begin position="79"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="domain" description="Polysaccharide lyase family 8 central" evidence="4">
        <location>
            <begin position="308"/>
            <end position="551"/>
        </location>
    </feature>
    <feature type="domain" description="Polysaccharide lyase family 8 C-terminal" evidence="5">
        <location>
            <begin position="581"/>
            <end position="643"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006699"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF02278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF02884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF08124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OBZ87324.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="676" mass="75538" checksum="23B0E3640C726023" modified="2016-11-30" version="1">MSSGCEARRANWPAIEHLSRTRYLATAYMMNTSDTVAFDAAMLALNYWINNDYNSTDCIRRGGNSKGNCPCGTPGLWNTNWYSQLIGVPKVLSDICIVLRSNLTENQRLGCEKIQMRSFNTVDDFTGANLLDATYVGITLGIFNQDANLTKSGLEKFYGGVVISPTVAGDGIQSDGSFMQHNGLLYNGNYGKDFINNLLHVFTLTKETELAPGVDVQDAFETLMSGTEWMILSDAKRKKLLWQYSVIGRMITFKHSDRQSSGGVSIDLKEISEGAEGWENEENIHDITNRLETVSADDANQGDLVGTRYFYNADYLVHRGTNYIVTLKMYSSRTVNSECVNTQNPYGFHLSDGAIYNYLSGDEYVDVFGAWDWELVPGITVDYGRTPLTCVKSKIKGKKKFVGGATDGNTGIAVMDFLNPMNGNLQFEKTFFFSPNGYSVQLGPIALKDQSSRLLTVLDQRRRNGDVYVNGNSESIDSTYNNSVVKSIWHDGIGYYFPFSETLQVDSRLKTSNWSNIGISQGSEEEQLWTSYIEHTFQNQAHEPLTQYIVQLGVNSSSFNKNAANSDMPIYLDYSLESQQVYSAYDIGEDVLAIAFWTAGQYTDPWKSMTVIANKPCVLLLRQLDTRVFRLTVADPSQTLKMVKITTKLDGKTQSYSLTMYTGNRAGKAKTKLITF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NJ74</accession>
    <name>A0A1C7NJ74_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">proline--tRNA ligase</fullName>
            <ecNumber evidence="2">6.1.1.15</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Prolyl-tRNA synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="primary">prs1</name>
        <name evidence="12" type="ORF">A0J61_04586</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>tRNA(Pro) + L-proline + ATP = L-prolyl-tRNA(Pro) + AMP + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:14305"/>
            <dbReference type="Rhea" id="RHEA-COMP:9700"/>
            <dbReference type="Rhea" id="RHEA-COMP:9702"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:60039"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78532"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.15"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the class-II aminoacyl-tRNA synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.15" evidence="2"/>
    <dbReference type="EMBL" id="LUGH01000227">
        <property type="protein sequence ID" value="OBZ87364.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NJ74"/>
    <dbReference type="FunCoup" id="A0A1C7NJ74">
        <property type="interactions" value="120"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NJ74"/>
    <dbReference type="InParanoid" id="A0A1C7NJ74"/>
    <dbReference type="OrthoDB" id="1350766at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017101">
        <property type="term" value="C:aminoacyl-tRNA synthetase multienzyme complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002161">
        <property type="term" value="F:aminoacyl-tRNA deacylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004827">
        <property type="term" value="F:proline-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006433">
        <property type="term" value="P:prolyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd00862">
        <property type="entry name" value="ProRS_anticodon_zinc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00778">
        <property type="entry name" value="ProRS_core_arch_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.110.30:FF:000001">
        <property type="entry name" value="Bifunctional glutamate/proline--tRNA ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.930.10:FF:000007">
        <property type="entry name" value="Bifunctional glutamate/proline--tRNA ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.800:FF:000005">
        <property type="entry name" value="bifunctional glutamate/proline--tRNA ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.800">
        <property type="entry name" value="Anticodon-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="entry name" value="Bira Bifunctional Protein, Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.110.30">
        <property type="entry name" value="C-terminal domain of ProRS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.960.10">
        <property type="entry name" value="YbaK/aminoacyl-tRNA synthetase-associated domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01571">
        <property type="entry name" value="Pro_tRNA_synth_type3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002314">
        <property type="entry name" value="aa-tRNA-synt_IIb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006195">
        <property type="entry name" value="aa-tRNA-synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004154">
        <property type="entry name" value="Anticodon-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036621">
        <property type="entry name" value="Anticodon-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002316">
        <property type="entry name" value="Pro-tRNA-ligase_IIa"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004499">
        <property type="entry name" value="Pro-tRNA-ligase_IIa_arc-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016061">
        <property type="entry name" value="Pro-tRNA_ligase_II_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017449">
        <property type="entry name" value="Pro-tRNA_synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033721">
        <property type="entry name" value="ProRS_core_arch_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036754">
        <property type="entry name" value="YbaK/aa-tRNA-synt-asso_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007214">
        <property type="entry name" value="YbaK/aa-tRNA-synth-assoc-dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00408">
        <property type="entry name" value="proS_fam_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43382:SF2">
        <property type="entry name" value="BIFUNCTIONAL GLUTAMATE_PROLINE--TRNA LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43382">
        <property type="entry name" value="PROLYL-TRNA SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03129">
        <property type="entry name" value="HGTP_anticodon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09180">
        <property type="entry name" value="ProRS-C_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00587">
        <property type="entry name" value="tRNA-synt_2b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04073">
        <property type="entry name" value="tRNA_edit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01046">
        <property type="entry name" value="TRNASYNTHPRO"/>
    </dbReference>
    <dbReference type="SMART" id="SM00946">
        <property type="entry name" value="ProRS-C_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64586">
        <property type="entry name" value="C-terminal domain of ProRS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52954">
        <property type="entry name" value="Class II aaRS ABD-related"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="Class II aaRS and biotin synthetases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55826">
        <property type="entry name" value="YbaK/ProRS associated domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50862">
        <property type="entry name" value="AA_TRNA_LIGASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 12" id="KW-0436">Ligase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aminoacyl-transfer RNA synthetases class-II family profile" evidence="11">
        <location>
            <begin position="249"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="661"/>
            <end position="681"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012831"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00029731"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00047671"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="OBZ87364.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="719" mass="80699" checksum="28846C7464D5705C" modified="2016-11-30" version="1">MSAFDTVLETLSKLSISPKTVSHDAVSDNKAWAEALTNTKDVSFEITKTLILKPKTAKTAAPTPVVVIALDATETNASALGKKLSLKDCRFASEDLLKDTFQAEKDSVSPFALSNVQDLSLIHLVVDSALLALPGSTLLAFHPSASDKTVFVTVDELKVFFQSIQKEWIEVDFKALAAAKPPATESKVAKAPKAAKKEAAPAEDFNQMGLGCRKEEDFPKWYQQVLTKSEMLEYYDVSGCYILRPLAYNVWKEITNFFDAEITEMGVEDTYFPMFVSNRVLQREKDHIEGFAPEVAWVTKAGSSDLEEPIAIRPTSETVMYPYFSKWIRSHRDLPFRINQWCSVVRWEFKNPQPFLRTREFLWQEGHTAHLNLESADKEVKEILDLYEQVYNDLLALPVVKGVKSEKERFAGGYYTTTVEGFIPTTGRAIQGGTSHCLGQNFSKMFNITVEDPSAPANATEEAKKLHVWQNSWGISTRTIGVMVMTHGDDKGLVMPPRVALIQTVIVPCGLTVKTTKEESDKIFDACQDVAARLKKAGLKSKADLRENYTPGFKFNHWEIRGVPLRLEVGPKDLEKNQVTCVRRDTGAKFSVSLDNLEAGVKEALDTIQNDMYQKAKKKMEDSIIRITKWEEFVPTLNNKKLLLVPWCDRTECEDDIKERSAKVANEGEEEDERAPSMGAKSLCKPFNQPTEDPIVPGVTKCIACEHDAKHFMLFGRSY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NJA6</accession>
    <name>A0A1C7NJA6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Putative transporter ESBP6</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">ESBP6_2</name>
        <name evidence="5" type="ORF">A0J61_02881</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000115">
        <property type="protein sequence ID" value="OBZ89068.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NJA6"/>
    <dbReference type="STRING" id="101091.A0A1C7NJA6"/>
    <dbReference type="InParanoid" id="A0A1C7NJA6"/>
    <dbReference type="OrthoDB" id="6499973at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050327">
        <property type="entry name" value="Proton-linked_MCT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11360:SF284">
        <property type="entry name" value="EG:103B4.3 PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11360">
        <property type="entry name" value="MONOCARBOXYLATE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="42"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="85"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="114"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="139"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="171"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="198"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="260"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="287"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="320"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="350"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="387"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="420"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="4">
        <location>
            <begin position="43"/>
            <end position="441"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OBZ89068.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="448" mass="49349" checksum="28D68B3AD61097FE" modified="2016-11-30" version="1">MNSLENTSFESSQATLYTKDIKRVCRTRSKESISDIPEQNPWLIVVGTFLVLVVGLGSLQSWGIMQNYFEQYPGFQGTPNLSLQLSFVATICNIIINLLGLVGQVLLSLFETRTVLFVSIVICSVGLLLASFSTQIWHLYLTQGVVYGIGSSIMFYIALSVVPQWFTKHKGMALGIISSGISIGGLIMPLIIEPLNTHLGAAWCYRIMSLICLVIGIISCLFFKTTKNSTEDNGEKQSQKEAIIQIKDLFDLSVAKNWRFLLWVFIDILMESAYNVPYYFLPSYATFLGLSTSQGALVLSVGSGMNAIGRIASGLIADVFGHVNVIIIYSIISGLTSLFLWTYATTFNTLMAFSVLFGFFGGAFITLTPTITLLVTGYEKFETGLSVFLILTVISMFGPNLAGVIEVSAHALKEFDSYKYFTGACYLTGAILLIVFKLSLNRNFFAKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NJF4</accession>
    <name>A0A1C7NJF4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_02730</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000107">
        <property type="protein sequence ID" value="OBZ89205.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="InParanoid" id="A0A1C7NJF4"/>
    <dbReference type="OrthoDB" id="2265959at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ89205.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="233" mass="26361" checksum="72351D04A0195B9A" modified="2016-11-30" version="1">MVFLSSTSALPAIYNKPYLIDMQHYSQLYSTHLIFEHLDGTLSNLTKQISYHLQDLIQVTIEPLSPKDDFVVDIDLLKGQLQGAVGSFVEDSLPNIWNTRAAVIDRSFLSSHIESITREHCPVQNGNYLTSTCIISQSPKIIXQVDQYIENHLKQIIRTIVMQDLPPLFRTTQDHVNGILGHFNHYIVQNNMSSNAYVVHKKLKEPTALINDLESAVNPHSSLQEFIALAKVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NJM9</accession>
    <name>A0A1C7NJM9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Ribonucleotide monophosphatase NagD</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">nagD_1</name>
        <name evidence="2" type="ORF">A0J61_02579</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000099">
        <property type="protein sequence ID" value="OBZ89362.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NJM9"/>
    <dbReference type="STRING" id="101091.A0A1C7NJM9"/>
    <dbReference type="InParanoid" id="A0A1C7NJM9"/>
    <dbReference type="OrthoDB" id="10251048at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016791">
        <property type="term" value="F:phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07530">
        <property type="entry name" value="HAD_Pase_UmpH-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006357">
        <property type="entry name" value="HAD-SF_hydro_IIA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01460">
        <property type="entry name" value="HAD-SF-IIA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19288">
        <property type="entry name" value="4-NITROPHENYLPHOSPHATASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19288:SF46">
        <property type="entry name" value="HALOACID DEHALOGENASE-LIKE HYDROLASE DOMAIN-CONTAINING PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13344">
        <property type="entry name" value="Hydrolase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13242">
        <property type="entry name" value="Hydrolase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ89362.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="382" mass="41577" checksum="5AD12D79DADC81F0" modified="2016-11-30" version="1">MSDNTATTPTTATPAATTPVATTPTVETPATPTVTTPTGHTLATQSGNEFASIDETRDLAASFAASLGQHQLNAVPSGKNEDGISPRDWALFKDPVLHNERLDAIRQKKGYIIDMDGVIYHGSKLLPGAKEFVDFLEKNNKKYLFLTNNSAPTPRELQQKLHRLGIDVTEDHFFTSGQATAHFLKSQMPEGGTCYVIGEPGLAYALYDKGFFMNDHNPDYVVLGESAVYNFEKLTKAVQLVQQGAKLISTNLDVETLDSQGRKIPATGAFTACVELVTKTKAFFCGKPSALIMRYAQRVLGLSRLETCIIGDRMDTDIVAGISSEIDPVLVLSGVTEMSDLALFAYHPYVILGGVYEIPNDDEKNMLTADELEEAARRASYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NJN9</accession>
    <name>A0A1C7NJN9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Translocon-associated protein subunit beta</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_02612</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000101">
        <property type="protein sequence ID" value="OBZ89327.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NJN9"/>
    <dbReference type="InParanoid" id="A0A1C7NJN9"/>
    <dbReference type="OrthoDB" id="2282137at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008889738" description="Translocon-associated protein subunit beta" evidence="2">
        <location>
            <begin position="22"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="141"/>
            <end position="161"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ89327.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="162" mass="17956" checksum="0A759D7D332CF07D" modified="2016-11-30" version="1">MMSKSLLAFFFTLLLLPYCFAQLGTQIYFPNSNDTVKPGQKIDIAYGYQNMGNGTYKVDIDVWQDSARSILAENIAQNVSVAPGNSTGTRLDFYLNNTYGWTVPHGLNSTVYLTVTTKADLASSLHLSMQSRGIMLHVNSAHITIPHFLWLFACIIALSIVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NK75</accession>
    <name>A0A1C7NK75_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">OV-16 antigen</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">OV16</name>
        <name evidence="2" type="ORF">A0J61_02551</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the phosphatidylethanolamine-binding protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000097">
        <property type="protein sequence ID" value="OBZ89398.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NK75"/>
    <dbReference type="STRING" id="101091.A0A1C7NK75"/>
    <dbReference type="InParanoid" id="A0A1C7NK75"/>
    <dbReference type="OrthoDB" id="2506647at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00866">
        <property type="entry name" value="PEBP_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.280.10">
        <property type="entry name" value="PEBP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008914">
        <property type="entry name" value="PEBP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036610">
        <property type="entry name" value="PEBP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035810">
        <property type="entry name" value="PEBP_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001858">
        <property type="entry name" value="Phosphatidylethanolamine-bd_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11362">
        <property type="entry name" value="PHOSPHATIDYLETHANOLAMINE-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11362:SF82">
        <property type="entry name" value="PHOSPHATIDYLETHANOLAMINE-BINDING PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01161">
        <property type="entry name" value="PBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49777">
        <property type="entry name" value="PEBP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01220">
        <property type="entry name" value="PBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ89398.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="179" mass="20603" checksum="B75B07F79B0FC111" modified="2016-11-30" version="1">MAEEIDYAAFKEHQVVPDVIPFEFRVSTELQISYPNSRQQVQLGNSLTPAEASEQPTVDFVPPQPSEKYTLVMTDPDAPSRTDPKFGPWRHWIVTNIDGQDVQKGLMDLNNHHTPYVGPGPPPNSGTHRYVFLLYRQRHEKNFAVMGTEREERRKFDLRAFETENELQLVSANFFICPT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NKB5</accession>
    <name>A0A1C7NKB5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">A0J61_03023</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000123">
        <property type="protein sequence ID" value="OBZ88936.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NKB5"/>
    <dbReference type="InParanoid" id="A0A1C7NKB5"/>
    <dbReference type="OrthoDB" id="2020419at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006004">
        <property type="term" value="P:fucose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11350">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019378">
        <property type="entry name" value="GDP-Fuc_O-FucTrfase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10250">
        <property type="entry name" value="O-FucT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="2" id="KW-0294">Fucose metabolism</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023253"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OBZ88936.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="429" mass="50123" checksum="A6EFCF38306411AA" modified="2016-11-30" version="1">MYSTQTEKSVVVPYAYPGRVKYSYQWPPSSSGKTRLYQDAKHIDRAFCGQDRCRFLLPVAITEQESKAQMHFRQLAFLAGQLNRTIVLPNVYHSHMGSCLPYSFDFYYDQEWLDRNDKHFKYITMAAFKQWIEARHQESAIPTGQEIYVQGSRKSKLLKRIKNCFYQAFDFSQRPVVNYQFLDHSKVPKDINLNKVMTSLLSDQARHHESALEEPVDVINLYYDRRYMFLHHPQAARPLSYNPHWSQVANQIVEQLKPFIAIHWRMERLEPVSNLLPCAKNLVEQVQQMNHTNVFLLTDYPHLLNNRPESNSFRPSQLVPEHHQAIEYLYRHLNVTLTAVAPVPSNVSDRWHVVPIQSTQDDRFPQDKSVLGIVDKLVAMQAQWFFAGKPDVCAKRSSFTARIIDSRKKAMKHHTQGDLEPVKTFDISV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NKJ1</accession>
    <name>A0A1C7NKJ1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_02419</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000091">
        <property type="protein sequence ID" value="OBZ89518.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NKJ1"/>
    <dbReference type="STRING" id="101091.A0A1C7NKJ1"/>
    <dbReference type="InParanoid" id="A0A1C7NKJ1"/>
    <dbReference type="OrthoDB" id="2248195at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008889750" evidence="1">
        <location>
            <begin position="18"/>
            <end position="260"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ89518.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="260" mass="29335" checksum="CA12EBCA9560F232" modified="2016-11-30" version="1">MISFVFICLFFITTLQALQVNFASSSSKDLLNRDSALSHYQSVLDDILSQHNEGLLTDLSMIIKDTDTMYAVLRPQASYLLEDPQDVCVAQMPGMIATQIHELSNTLYAQVDAIVLDSWRASDTEIRQLILNAINQGSWEQDVLDELADHLEMVNMEIADRLLNVVHEFDFLDKIKWSLVKCQAVFDAPSQPANSLTEKIWTAILVSLRNEPLSEDRITSSGHGLLNRYLSELVLDLQGELYGRTFELATSIYEDLAFNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NL74</accession>
    <name>A0A1C7NL74_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">40S ribosomal protein S22</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">RPS22A_0</name>
        <name evidence="5" type="ORF">A0J61_02078</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the universal ribosomal protein uS8 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000074">
        <property type="protein sequence ID" value="OBZ89872.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NL74"/>
    <dbReference type="FunCoup" id="A0A1C7NL74">
        <property type="interactions" value="458"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NL74"/>
    <dbReference type="InParanoid" id="A0A1C7NL74"/>
    <dbReference type="OrthoDB" id="10250260at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1370.30:FF:000001">
        <property type="entry name" value="40S ribosomal protein S15a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1490.10:FF:000002">
        <property type="entry name" value="40S ribosomal protein S15a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1370.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01302_A">
        <property type="entry name" value="Ribosomal_uS8_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000630">
        <property type="entry name" value="Ribosomal_uS8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047863">
        <property type="entry name" value="Ribosomal_uS8_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035987">
        <property type="entry name" value="Ribosomal_uS8_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003115">
        <property type="entry name" value="PRK04034.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11758">
        <property type="entry name" value="40S RIBOSOMAL PROTEIN S15A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00410">
        <property type="entry name" value="Ribosomal_S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56047">
        <property type="entry name" value="Ribosomal protein S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00053">
        <property type="entry name" value="RIBOSOMAL_S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 5" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003660"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OBZ89872.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="130" mass="14688" checksum="8EB45911FF34337A" modified="2016-11-30" version="1">MVRVSVLNDCLNSINNAEKRGKRQVLVRPSSKVIVKFLTVMQKNGYIGEFEIVDDHRSGKIVIQLIGRINKCGVISPRFNIKYSELEKWTANLLPARQFGHLVLTTSAGIMDQDEARQKHVGGKVLGFFY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NL94</accession>
    <name>A0A1C7NL94_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_02221</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000080">
        <property type="protein sequence ID" value="OBZ89730.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NL94"/>
    <dbReference type="InParanoid" id="A0A1C7NL94"/>
    <dbReference type="OrthoDB" id="2230412at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="163"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="170"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="191"/>
            <end position="205"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ89730.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="589" mass="67156" checksum="D8194A8CA93D198F" modified="2016-11-30" version="1">MTANKRKQKEATSKSIPKTFKRACLANLPGSTVLSKDLAKILKVPGFIATLEVRQWKQEATLVRSYFQHTDIPENTSNQLITVLNGALQRIIKNENADAKLKCYSVALVRQFKTEKSKQRFNMEYRKLFNGYQVEKLEEEAQTEARVISRILTTVEAKAHRKNTQSRLDQLIKHDETDRYTDDNAHSDLESGSEDENDCPSEEETAGELSFAFTQAFADDSEAVGSVSSPNGNIDDLFAEEEEFPTLKVVKEKSIYKYQAPAQNIVSPHKPIIQAIDLGVLKDYFDICIGTNQDKATEETKQEFVAYMNEQNLYKSLKEMPAEIYDKLLTILQIQDRLKMKKIIMDLPAESSAFTEFVQYALLDFTLNLSKPSSFDGKNDERSIFCEVFIPIFKAFGNCLSVLNFTWCEKKAKDADYVWLVSNDFSKRNKDNLKLIDGVGTLTKINSTYLLMESSGFNHTSVVSHSLNDTLKNIKNGHDNLKYLFSQYRNASFNTIKKVNIFSCQIIENKITLIKYAVKSRTTWKVVECRSASVPLTIESSLYYVKVFELFAFMLNNIQKQQSVFNQLKLENLGLVPVPKHETVAHCLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NLG5</accession>
    <name>A0A1C7NLG5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">N-acetylglucosaminylphosphatidylinositol deacetylase</fullName>
            <ecNumber evidence="2">3.5.1.89</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">gpi12</name>
        <name evidence="3" type="ORF">A0J61_02003</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the PIGL family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.5.1.89" evidence="2"/>
    <dbReference type="EMBL" id="LUGH01000071">
        <property type="protein sequence ID" value="OBZ89947.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NLG5"/>
    <dbReference type="FunCoup" id="A0A1C7NLG5">
        <property type="interactions" value="303"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NLG5"/>
    <dbReference type="InParanoid" id="A0A1C7NLG5"/>
    <dbReference type="OrthoDB" id="440160at2759"/>
    <dbReference type="UniPathway" id="UPA00196"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000225">
        <property type="term" value="F:N-acetylglucosaminylphosphatidylinositol deacetylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006506">
        <property type="term" value="P:GPI anchor biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10320">
        <property type="entry name" value="LmbE-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003737">
        <property type="entry name" value="GlcNAc_PI_deacetylase-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024078">
        <property type="entry name" value="LmbE-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12993:SF11">
        <property type="entry name" value="N-ACETYLGLUCOSAMINYL-PHOSPHATIDYLINOSITOL DE-N-ACETYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12993">
        <property type="entry name" value="N-ACETYLGLUCOSAMINYL-PHOSPHATIDYLINOSITOL DE-N-ACETYLASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02585">
        <property type="entry name" value="PIG-L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102588">
        <property type="entry name" value="LmbE-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006066"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ89947.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="249" mass="28572" checksum="1DD58144795184BD" modified="2016-11-30" version="1">MLSVILSLVFIVSLLTYAYFSLAHFEKVLPFKNSTILLLTAHPDDECMFFGPTLTSLKTLTKARIHVLCLSTGNAEGLGIQRKKELTKSCQVFGISPNHIKSMDHAHLQDGMHHQWDKALIAQTLRDYVVKHKIDTIITFDDHGVSGHPNHIALYHGAKHFVQQRPNVTLYRLESVSLVRKYIGFADLLIPKKPNSLQLVSPPLAYLLTHKAMRQHESQLVWFRWLYVTFSRFMYVNNLVREEVAIEIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NLU9</accession>
    <name>A0A1C7NLU9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">A0J61_01883</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000065">
        <property type="protein sequence ID" value="OBZ90067.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NLU9"/>
    <dbReference type="STRING" id="101091.A0A1C7NLU9"/>
    <dbReference type="InParanoid" id="A0A1C7NLU9"/>
    <dbReference type="OrthoDB" id="6365676at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000446">
        <property type="entry name" value="Zinc finger protein"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000072">
        <property type="entry name" value="zinc finger protein 143 isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23235">
        <property type="entry name" value="KRUEPPEL-LIKE TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23235:SF120">
        <property type="entry name" value="KRUPPEL-LIKE FACTOR 15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="7">
        <location>
            <begin position="169"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="7">
        <location>
            <begin position="199"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="7">
        <location>
            <begin position="418"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="7">
        <location>
            <begin position="448"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="146"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="317"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="379"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="459"/>
            <end position="508"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="318"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="332"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="388"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="473"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="488"/>
            <end position="508"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OBZ90067.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="508" mass="58004" checksum="6357EB0AA4D2F3E9" modified="2016-11-30" version="1">MNPKIIHYEQPETPLINEKLPSIDTFAKSDEMKDSVAHYLPPPPNAFNMLYSQHVSPPLTPAVSPSSILFDSMNFKRKFSIDISPFGFGTNLSPSMQDAYRRSSCSAMDSMPPNPTMPANGYSVAVTAAAQAIHAARSPIDYTFLNPTVKKPSRKTSRTQPGPSTQHKHACKYPYCTWSFKRYEHLKRHMLVHTGKRPHVCHFPGCGKSFSRSDNFHAHYRTHTKKANLLQNKTSPKQDLQTTSMSEQVAVCEASTDGSPVTEVMAMPSFEERSYYGHLEIKQPSPSFDMTPYQDIYQRYHSEEPYQQQYMRHFPQQLFPSPTTSSSDDLQSTITSPISPSGTSLLNHEQQNSFYLQTLHSPTSRFSYPMNPYAYQNYPDDIVPLPENTTPTTKPNNNRSNNKSSTPRKSSNDQLKSHICPVTQCQRRFKRLEHLKRHMRIHTLERPFGCSFPNCHKTFSRSDNLSQHMKTHQRVEDRRRKPQKETSKSNLPYPTQASDSSAMIVNMS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NMC6</accession>
    <name>A0A1C7NMC6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Putative J domain-containing protein C3E7.11c</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">A0J61_01647</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000055">
        <property type="protein sequence ID" value="OBZ90301.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NMC6"/>
    <dbReference type="FunCoup" id="A0A1C7NMC6">
        <property type="interactions" value="411"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NMC6"/>
    <dbReference type="InParanoid" id="A0A1C7NMC6"/>
    <dbReference type="OrthoDB" id="552049at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.110:FF:000028">
        <property type="entry name" value="DnaJ domain protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018253">
        <property type="entry name" value="DnaJ_domain_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026894">
        <property type="entry name" value="DnaJ_X"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44924">
        <property type="entry name" value="DNAJ SUBFAMILY A MEMBER 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44924:SF1">
        <property type="entry name" value="DNAJ SUBFAMILY A MEMBER 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14308">
        <property type="entry name" value="DnaJ-X"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00625">
        <property type="entry name" value="JDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00636">
        <property type="entry name" value="DNAJ_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0143">Chaperone</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="J" evidence="3">
        <location>
            <begin position="80"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="189"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="419"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="433"/>
            <end position="443"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OBZ90301.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="443" mass="50002" checksum="F3EE66F0206CA723" modified="2016-11-30" version="1">MPYSSRKPEPYLQTSCKYCTQPFEFLPAPNTRSTRVEVECWSCQSIVQVEIDSAGKVKPSRPTSKWSRKRGTDQEPVSTEYYDCLGVMPSATQADIKKAYRKLAIKYHPDKNPNDPTAEEKFKKISEAYQVLSDPELRKQYNEFGEQNGPDGGFMDPEAFFKQAFGGDRFVDIIGEMSIGREMRDALETHEAEEGSNDSKTLSIEEKSEREEAKRKIRAEAKEKRVATLVNKLINKLSLYTELNDISEEARTAAFSNIIQIEAEDLKKESHGVELLNAIGYTYLTKATQYINRGVAFGLGGMFHSMKEKSYIFSETVGTIRSAYDLQSSYTELQKAEEKGDLTEEQRIKLETEAATKGLKAIWRGSKLEVESVLREVCDRVLNDPTVSRETLRQRALGLKIIGTIYQKVKLEVTPDDIPIPSVSEDPLDAHNVKSTKTHSTSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NMQ6</accession>
    <name>A0A1C7NMQ6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_03400</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000145">
        <property type="protein sequence ID" value="OBZ88544.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NMQ6"/>
    <dbReference type="STRING" id="101091.A0A1C7NMQ6"/>
    <dbReference type="InParanoid" id="A0A1C7NMQ6"/>
    <dbReference type="OrthoDB" id="5599619at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="406"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="130"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="214"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="331"/>
            <end position="365"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ88544.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="460" mass="54217" checksum="C1E7844D8A8E5DE9" modified="2016-11-30" version="1">MNNEDVEEYINVLFSKSTKGERATACTIDWLDFLQEYNVQQGYYVLTEDELQEMEAYCAANPDLEMTPDEFVRLIYTVRDLPDDSIGSYYPVQDNTTGYFQDRESTNHPGPQIQTSPRLVSSNLKPKVAVPKESQLLRQLRQENEQLLRKYEKQLDNLNSLSERIGLLESRLEAAKLESSQQKAVIDSCKNKEKERQETIAHLRLLVNDYETNHDQDQIKLNQKDDELQELQQQLHEIQTSHQSTLSCLEVAERDLYQIKEHMRQQEKQKLEQADQSRQYDSEIQHLQQENSRLLGVIDKQKFDLDEARASRYVMDKRDNTTQEQLQLDYEEKLNRTIDQHQQIIETLENELNEAQRQNQLDQQIQHELRQKIATLSTQFDHQHELIQVIQKKLSLSAIPSPTHQFFYLLSILPWVFFLYHLLIYLIETVYGLSRRDSIHTSFNIASFLLGRLDELLRGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NN42</accession>
    <name>A0A1C7NN42_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_01389</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000043">
        <property type="protein sequence ID" value="OBZ90561.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NN42"/>
    <dbReference type="InParanoid" id="A0A1C7NN42"/>
    <dbReference type="OrthoDB" id="2268330at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12937">
        <property type="entry name" value="F-box-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="1">
        <location>
            <begin position="10"/>
            <end position="41"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12937"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ90561.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="617" mass="72039" checksum="401E738946A50D1E" modified="2016-11-30" version="1">MRPTNFVDYVPNELLIGIFNLLPKDSQGNCLCVCKSWYYVFAYIHYRNITIGDRDEQDKIALFARFLKERPPNVGGGIRTLQINQRPSRLCTEKEAKSARQALGKILVSCNNLKELGMTVDSQYWKYMYELSQEPHIPKLHKISALGMITHRHRQDYFYKVAHQHRSTLKKLDVHRSCDQSIQKEFHGLLNYLKDFKQLERLSIKSGSQQELIFFHRLLEVCPQLEALDYQLDHPFFDCNPTNVSIYPTLRELDIYLPDFSSRLLKYVTERFQSLKRLTIRVNHSDSTQQSRWSKSETGDTLTKALYFFGNQFISFIRQLEYSQLNFCINGKSYIEPYIAQIYCSQISMNSKEVNADFQLTDSRAEMSQMTLIKGVDNVDFRFHFVREFDSLQHDLLYLEHLRSYGSRLQKLKITYNRQDGLATAIDLNPILSLCPNLSTLSISIQASPSVYFSHPHASIFPPLILSEAAQTVDPHIAHVVLEGMSITPEFLKNLSVRLPNMRSFVIRNCIASFESNQFYDMSCLDIESFQFDISTHQRARVDDRESFCFVLERKFKRTLKYYLVNETQPKELTESQFNERKGQLPVIWFMFNTLKKAELHATNKALCAKEILFCNN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NNA8</accession>
    <name>A0A1C7NNA8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">25S rRNA (Uridine-N(3))-methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">bmt5</name>
        <name evidence="3" type="ORF">A0J61_01333</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000041">
        <property type="protein sequence ID" value="OBZ90613.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NNA8"/>
    <dbReference type="FunCoup" id="A0A1C7NNA8">
        <property type="interactions" value="283"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NNA8"/>
    <dbReference type="InParanoid" id="A0A1C7NNA8"/>
    <dbReference type="OrthoDB" id="273345at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070042">
        <property type="term" value="F:rRNA (uridine-N3-)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070475">
        <property type="term" value="P:rRNA base methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019446">
        <property type="entry name" value="BMT5-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11538:SF26">
        <property type="entry name" value="FERREDOXIN-FOLD ANTICODON-BINDING DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11538">
        <property type="entry name" value="PHENYLALANYL-TRNA SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10354">
        <property type="entry name" value="BMT5-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="25S rRNA (uridine-N(3))-methyltransferase BMT5-like" evidence="2">
        <location>
            <begin position="66"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="20"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="291"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="20"/>
            <end position="41"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF10354"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ90613.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="328" mass="37313" checksum="1AA96C15E9FB546B" modified="2016-11-30" version="1">MGKLKRKKLANALGRLLTKVDKRKEKERRANAHTENSERAKQGQIKKISPKTSHVRPQYNSKDRILLVGEGNFSFARSLCENYLEEGAEHLVATCYDSEEVLYEKYSEEAKENVELVREFGATVLFGIDATDFPKEIKKKKYTKIVFNFPHVGAGIKDQDRNVIANQKLLNGFLDAATPLLTKAGYQFPNTEENLRISDDEPAPEGEIHITLKTSKPYNLWAVKSLVKAKGELAVKSTSPFYVDDFPGYEHRRTLGFKKGLSKDENAEIISSEPKRYVFVRKEVMEGEIQNSIKGSQKRKLEDLKAKMGKKVKRKKTDDLQPNDEDDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NNJ9</accession>
    <name>A0A1C7NNJ9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_03107</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000128">
        <property type="protein sequence ID" value="OBZ88844.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NNJ9"/>
    <dbReference type="InParanoid" id="A0A1C7NNJ9"/>
    <dbReference type="OrthoDB" id="2364397at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="70"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="99"/>
            <end position="122"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ88844.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="145" mass="16601" checksum="6ECBB0816DE7E039" modified="2016-11-30" version="1">MSATTQVVHVVSEIYNFCYMHLKDSDTPLPSANQVVSYVKMFINFVLQHSPSIVQQWYGPFTKFLIDSNFINMFIALFIVYICWLFVKATFLGAYRLIYGFVRTSFIIVGLLLLLSAVNYIMTISGYSVDATSNSGTTRTFQYQH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NPX0</accession>
    <name>A0A1C7NPX0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Elongation factor 1-beta</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">eef1b_1</name>
        <name evidence="8" type="ORF">A0J61_01016</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the EF-1-beta/EF-1-delta family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000027">
        <property type="protein sequence ID" value="OBZ90949.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NPX0"/>
    <dbReference type="FunCoup" id="A0A1C7NPX0">
        <property type="interactions" value="746"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NPX0"/>
    <dbReference type="InParanoid" id="A0A1C7NPX0"/>
    <dbReference type="OrthoDB" id="331763at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005853">
        <property type="term" value="C:eukaryotic translation elongation factor 1 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005085">
        <property type="term" value="F:guanyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00292">
        <property type="entry name" value="EF1B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.60:FF:000001">
        <property type="entry name" value="Elongation factor 1-beta 1 like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1050.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036219">
        <property type="entry name" value="eEF-1beta-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018940">
        <property type="entry name" value="EF-1_beta_acid_region_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049720">
        <property type="entry name" value="EF1B_bsu/dsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014038">
        <property type="entry name" value="EF1B_bsu/dsu_GNE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036282">
        <property type="entry name" value="Glutathione-S-Trfase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014717">
        <property type="entry name" value="Transl_elong_EF1B/ribsomal_bS6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001326">
        <property type="entry name" value="Transl_elong_EF1B_B/D_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11595">
        <property type="entry name" value="EF-HAND AND COILED-COIL DOMAIN-CONTAINING FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11595:SF21">
        <property type="entry name" value="ELONGATION FACTOR 1-BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10587">
        <property type="entry name" value="EF-1_beta_acid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00736">
        <property type="entry name" value="EF1_GNE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01182">
        <property type="entry name" value="EF-1_beta_acid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00888">
        <property type="entry name" value="EF1_GNE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54984">
        <property type="entry name" value="eEF-1beta-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47616">
        <property type="entry name" value="GST C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00824">
        <property type="entry name" value="EF1BD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00825">
        <property type="entry name" value="EF1BD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4 8" id="KW-0251">Elongation factor</keyword>
    <keyword evidence="3 4" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008889819" evidence="5">
        <location>
            <begin position="20"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="domain" description="Elongation factor 1 beta central acidic region eukaryote" evidence="7">
        <location>
            <begin position="76"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="domain" description="Translation elongation factor EF1B beta/delta subunit guanine nucleotide exchange" evidence="6">
        <location>
            <begin position="112"/>
            <end position="198"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007411"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022768"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003791"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00888"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM01182"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OBZ90949.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="198" mass="21731" checksum="287741E8A0504F8B" modified="2016-11-30" version="1">MSVTLELPLALHILEAVLAENKFVASNDKATEADAAVAKALGSAPAAEFANVNKWYSEVKPSEAAPAEEDEDDIDLFGSDDEEVDEEAERVKAQRIAEYNAKKANKPKTIAKTTVTLDVKPWDDETNMEELTKAVKEINQDGLLWGGHQLVAIGYGIKKLQINCVVEDDKVLMDDLTEQILALEDYVQSVDIAAMQKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NQ09</accession>
    <name>A0A1C7NQ09_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">SH3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">A0J61_00963</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000026">
        <property type="protein sequence ID" value="OBZ90989.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NQ09"/>
    <dbReference type="STRING" id="101091.A0A1C7NQ09"/>
    <dbReference type="InParanoid" id="A0A1C7NQ09"/>
    <dbReference type="OrthoDB" id="196165at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051286">
        <property type="term" value="C:cell tip"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015630">
        <property type="term" value="C:microtubule cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030950">
        <property type="term" value="P:establishment or maintenance of actin cytoskeleton polarity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008104">
        <property type="term" value="P:intracellular protein localization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd17043">
        <property type="entry name" value="RA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.30.40:FF:000035">
        <property type="entry name" value="SH3 domain containing protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.40">
        <property type="entry name" value="SH3 Domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053039">
        <property type="entry name" value="Polarity_Bud-Selection_Reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000159">
        <property type="entry name" value="RA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036028">
        <property type="entry name" value="SH3-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001452">
        <property type="entry name" value="SH3_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47775">
        <property type="entry name" value="BUD SITE SELECTION PROTEIN 14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47775:SF1">
        <property type="entry name" value="BUD SITE SELECTION PROTEIN 14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00788">
        <property type="entry name" value="RA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00018">
        <property type="entry name" value="SH3_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00314">
        <property type="entry name" value="RA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00326">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50044">
        <property type="entry name" value="SH3-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50200">
        <property type="entry name" value="RA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50002">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0728">SH3 domain</keyword>
    <feature type="domain" description="SH3" evidence="4">
        <location>
            <begin position="65"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="domain" description="Ras-associating" evidence="5">
        <location>
            <begin position="330"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="192"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="271"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="638"/>
            <end position="657"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="677"/>
            <end position="722"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="20"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="42"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="207"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="695"/>
            <end position="720"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50200"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OBZ90989.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="758" mass="86254" checksum="274151EC3E3D3A55" modified="2016-11-30" version="1">MKQSSIVSSPIISSPVTTVYEEEEEEEEEEEEGVFENSNEYNNEEGEDDDSSMYSSSSSIPDENINFDLVYALHTFVATVDGQASVVKGDAMTLLDDSNSYWWLIRALKTSEVGYIPAENIETPFERLARLNKHRNVEVTSLGQLQHYQTSPEKKNRVKKKKVKVSRELACQLQVILTDEDDENVYEETFEKWDEDMSPEAYRDHEEDCEEEEEEEDEEDEEDDEEEEEVIPIEKKHAPLLNPDFNKPIDLTASSPLTSFVNHTITHKPLPAIQPQEPVPEKLPQEQPQQPQNSGKVTGLKRLLSIGKKNKLPQADPASSTETNNDTQYHVLRVFAGNINVGALFCTVALTPDMNADQLVKIALEKFHIPLLDESNKANEGIEYYLTVKSMDSDEKTLLPQDKPLAIFESLSDHLTTPMPSLTYIKRLSMEQPTIKVTRVGVSKARQRAKARFGEDSVIRFALHKRIKRTIETSGQIYVKISYHVDNKKHHRRLLNSQQQQQQQQKIPAMGLIRKSSLLRVDQQIQQQQQSLLQAKAKQERIDKLVAVSLTTEMLALTHIALEKFHLTEEDPTLYYIALSVNGKETAMHGQRTISDILSDSKLIPNGTAEKLFVLRKSVHTEPTDPTNRRFMRFLKQEKDSSRSLDSEQPGETSTGSVLKRLDTAIQSLEHDMRQFENGLPHIKVAPKEDKKIRNPSNNAQKPPPTNERTLPTRTSSLKVNKSDAFDTVNRNEFSNMDDLEQELKRIATSHSSATVRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NQC4</accession>
    <name>A0A1C7NQC4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">11-beta-hydroxysteroid dehydrogenase 1B</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">HSD1</name>
        <name evidence="6" type="ORF">A0J61_02472</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Putative oxidoreductase.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000094">
        <property type="protein sequence ID" value="OBZ89464.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NQC4"/>
    <dbReference type="STRING" id="101091.A0A1C7NQC4"/>
    <dbReference type="InParanoid" id="A0A1C7NQC4"/>
    <dbReference type="OrthoDB" id="2102561at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05233">
        <property type="entry name" value="SDR_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44196">
        <property type="entry name" value="DEHYDROGENASE/REDUCTASE SDR FAMILY MEMBER 7B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44196:SF1">
        <property type="entry name" value="DEHYDROGENASE_REDUCTASE SDR FAMILY MEMBER 7B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="178"/>
            <end position="198"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00037096"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OBZ89464.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="310" mass="33651" checksum="43BC46FE03080C24" modified="2016-11-30" version="1">MYRFCAAVRDLLLNIAIIFASYASLPITGWDVIKTSLCSLFNKKTHVPRVVAITGSSSGIGEGIAHAFAEDGVSLVLIARDLERLNKVARDCKELGSPNVKTVQLDVTDTQAVYAQLPEKILEYNVDLFIANAGIAFIPETPILDQAEDVFQLNVLGTIACVNAAYKSMKQRGRGGQIAAVSSGGVFFAPAFMVAYTASKAAVMSYCRDLRVLGKDDGITVNTIAPGYIDTPMTAVLPKKVGSLYITAEKHGRLVKRSLEEDVPVISFPSYQYLSLSMISALPPAVKQIAARLVHFIADPVFRDRYKVDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NQU4</accession>
    <name>A0A1C7NQU4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">HAUS augmin-like complex subunit 6 N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">A0J61_00432</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000009">
        <property type="protein sequence ID" value="OBZ91515.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NQU4"/>
    <dbReference type="InParanoid" id="A0A1C7NQU4"/>
    <dbReference type="OrthoDB" id="10552490at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028163">
        <property type="entry name" value="HAUS_6_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14661">
        <property type="entry name" value="HAUS6_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008889828" description="HAUS augmin-like complex subunit 6 N-terminal domain-containing protein" evidence="2">
        <location>
            <begin position="20"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="domain" description="HAUS augmin-like complex subunit 6 N-terminal" evidence="3">
        <location>
            <begin position="11"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="248"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="394"/>
            <end position="421"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF14661"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OBZ91515.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="421" mass="49345" checksum="2B18DA5EF8CE029D" modified="2016-11-30" version="1">MFTYSHALVVCLNLLGLQGSIPTQNPYIQVCIDESLFLDPEKARLHFMTITFYLFCCLDFQRAFSSLKPYWPTESRLEEKKYIQNALAWLEELDQSGCLLSYVPLTNVFFTECAGPVMQKIMFVFSLTVMQRLIDNNFKTDLPAAQSVDPIKLKAEADYFSKQFLEVEENALYYDNTDERHLYFEKTIIQHLKTYPLREGYMRAIKSYLEQGCHYYRTRKTTQQSKATNIYNKHPSHRTTAYFDSTTRVDDTKDTQNNSMSYKQKTKQLEEPIPPPSLPPPTMYRKPSDTGFHFTKPKDKHQLKNPFHDNNTSTLLKQVFSDSEEDEDRVEVGRGSQIKDFLSPPQKRDIRAALMGIKRDKGKEIEAGFRFPIEHRHSFQPNQLPVDPICQQIESQNSSRSKRKHIHLPEYSIKRIHRERH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NQY4</accession>
    <name>A0A1C7NQY4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">DNA replication regulator SLD2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">A0J61_02265</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000083">
        <property type="protein sequence ID" value="OBZ89674.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NQY4"/>
    <dbReference type="InParanoid" id="A0A1C7NQY4"/>
    <dbReference type="OrthoDB" id="8775810at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.1460">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021110">
        <property type="entry name" value="DNA_rep_checkpnt_protein"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11719">
        <property type="entry name" value="Drc1-Sld2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="68"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="137"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="191"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="68"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="91"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="148"/>
            <end position="165"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OBZ89674.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="351" mass="41074" checksum="113D5DA061335816" modified="2016-11-30" version="1">MNDEEYELLQRKIIRTKKDLRRWESVFAEKHDRPPTIKDISDRPNIEKFYKKYNQLKKELKRASDARALEKHIGSPHRQQESIEFVRSPHRSSPTQRGMISSQQTVTSLSEFEDMKNTVTTSTTATTNLAEDEAFWLGVSQSPPPPSSTTSTNTNSQPRLILGGSQKKKKKSLLKEQELLGRHTFHRRHLHHFQQKEEEQNQPPPVKQTTNSDHDDDDDDDMEGIEIVNHVVDPFRHYDPSVFHWEDPSFTIGPGFFGAATKVTMMLNDPMRRDRVLRKLEKGTLGEVLEENQAMEDELEEEIRQFIAQHHIIDHTIPPETTQTEKAFVYKKRPLQKRQTRLYKLKFVETR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NR87</accession>
    <name>A0A1C7NR87_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Cytochrome c oxidase copper chaperone</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="primary">COX17</name>
        <name evidence="16" type="ORF">A0J61_00471</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Copper metallochaperone essential for the assembly of the mitochondrial respiratory chain complex IV (CIV), also known as cytochrome c oxidase. Binds two copper ions and delivers them to the metallochaperone SCO1 which transports the copper ions to the Cu(A) site on the cytochrome c oxidase subunit II (MT-CO2/COX2).</text>
    </comment>
    <comment type="subunit">
        <text evidence="12">Interacts with COA1. Interacts with the chaperone CHCHD4; this is important for correct folding and the formation of disulfide bonds that stabilize the structure.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Mitochondrion intermembrane space</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the COX17 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000010">
        <property type="protein sequence ID" value="OBZ91480.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NR87"/>
    <dbReference type="FunCoup" id="A0A1C7NR87">
        <property type="interactions" value="159"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NR87"/>
    <dbReference type="InParanoid" id="A0A1C7NR87"/>
    <dbReference type="OrthoDB" id="1915887at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005758">
        <property type="term" value="C:mitochondrial intermembrane space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016531">
        <property type="term" value="F:copper chaperone activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005507">
        <property type="term" value="F:copper ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033617">
        <property type="term" value="P:mitochondrial respiratory chain complex IV assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.1130:FF:000001">
        <property type="entry name" value="cytochrome c oxidase copper chaperone"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.1130">
        <property type="entry name" value="CytochromE C oxidase copper chaperone"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009069">
        <property type="entry name" value="Cys_alpha_HP_mot_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007745">
        <property type="entry name" value="Cyt_c_oxidase_Cu-chaperone"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16719">
        <property type="entry name" value="CYTOCHROME C OXIDASE COPPER CHAPERONE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16719:SF0">
        <property type="entry name" value="CYTOCHROME C OXIDASE COPPER CHAPERONE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05051">
        <property type="entry name" value="COX17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47072">
        <property type="entry name" value="Cysteine alpha-hairpin motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0007">Acetylation</keyword>
    <keyword evidence="10" id="KW-0143">Chaperone</keyword>
    <keyword evidence="7 14" id="KW-0186">Copper</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5 14" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="15">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="27"/>
        </location>
        <ligand>
            <name>Cu cation</name>
            <dbReference type="ChEBI" id="CHEBI:23378"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="28"/>
        </location>
        <ligand>
            <name>Cu cation</name>
            <dbReference type="ChEBI" id="CHEBI:23378"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022990"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00055863"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00065132"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00071062"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PIRSR" id="PIRSR607745-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="OBZ91480.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="67" mass="7412" checksum="558C51A0051C644C" modified="2016-11-30" version="1">MAESVKTTSTHSGELPIGKDGKPLKPCCACPETKKVRDECIFMKGEENCQELIQAHLSCMRNLGFKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NRA4</accession>
    <name>A0A1C7NRA4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">BHLH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">A0J61_00519</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000011">
        <property type="protein sequence ID" value="OBZ91459.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NRA4"/>
    <dbReference type="STRING" id="101091.A0A1C7NRA4"/>
    <dbReference type="InParanoid" id="A0A1C7NRA4"/>
    <dbReference type="OrthoDB" id="5778525at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.280.10">
        <property type="entry name" value="Helix-loop-helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011598">
        <property type="entry name" value="bHLH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036638">
        <property type="entry name" value="HLH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052207">
        <property type="entry name" value="Max-like/E-box_TFs"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15741">
        <property type="entry name" value="BASIC HELIX-LOOP-HELIX ZIP TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15741:SF27">
        <property type="entry name" value="TRANSCRIPTION FACTOR AP-4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00010">
        <property type="entry name" value="HLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00353">
        <property type="entry name" value="HLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47459">
        <property type="entry name" value="HLH, helix-loop-helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50888">
        <property type="entry name" value="BHLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="BHLH" evidence="7">
        <location>
            <begin position="217"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="120"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="180"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="211"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="361"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="125"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="211"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="370"/>
            <end position="389"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50888"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OBZ91459.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="403" mass="46516" checksum="06415618026F2889" modified="2016-11-30" version="1">MSYSNHHMEWPYHLNNGNQTSSLNEAPLQEPVAFEDFQFSLGLDPNFSMPVPLDMMPPPSQPMTDTDFFGSITQPPPPNMTVLDEQDHKAFDQFLDQFYVDPNMQIDPQIMCNSLMPSSYYSPRNSKEEKEEEEYRQSSILQSLDEHQRRFVNEKPLPPSFHQTHNMTLLPPPHYQQYQPTNEFKQPYYPNSNNSSGSGGGAIRRAKPHKELLTEEEKRNNHIASEQKRRSMIRSGFKDLTEIVPTLKNINNSKSTVLFKAVDFIKYLEKRNKSLREKIKHLEVRVEVEGRMSVLNHPPNLKDTSMKTTSIPIHTTSTSSSSLPASIPPAPFQQTHAALLQHKTQQKQLMELQEKLQLHQRALAQKTHTFHYEKPQSKERESKKQDNNKNESNPKLLKTTVSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NRG2</accession>
    <name>A0A1C7NRG2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Serine/threonine-protein kinase 32A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">Stk32a_1</name>
        <name evidence="10" type="ORF">A0J61_00435</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="7">Belongs to the protein kinase superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000009">
        <property type="protein sequence ID" value="OBZ91519.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NRG2"/>
    <dbReference type="FunCoup" id="A0A1C7NRG2">
        <property type="interactions" value="135"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NRG2"/>
    <dbReference type="InParanoid" id="A0A1C7NRG2"/>
    <dbReference type="OrthoDB" id="354826at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001664">
        <property type="term" value="F:G protein-coupled receptor binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004703">
        <property type="term" value="F:G protein-coupled receptor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007186">
        <property type="term" value="P:G protein-coupled receptor signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009966">
        <property type="term" value="P:regulation of signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000354">
        <property type="entry name" value="AGC/YANK protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000210">
        <property type="entry name" value="Non-specific serine/threonine protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000961">
        <property type="entry name" value="AGC-kinase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24355">
        <property type="entry name" value="G PROTEIN-COUPLED RECEPTOR KINASE/RIBOSOMAL PROTEIN S6 KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24355:SF30">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE 32B ISOFORM X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51285">
        <property type="entry name" value="AGC_KINASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 10" id="KW-0418">Kinase</keyword>
    <keyword evidence="3 6 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 7" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="8">
        <location>
            <begin position="22"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="domain" description="AGC-kinase C-terminal" evidence="9">
        <location>
            <begin position="282"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="51"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="non-terminal residue" evidence="10">
        <location>
            <position position="396"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OBZ91519.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="396" mass="45623" checksum="BC9FE004FE833267" modified="2016-11-30" version="1" fragment="single">MGSFCCKEEPVDLMSEVELSHFALLRSVGKGAFGKVRVVQHKGTKKLYALKYINKDKCLEMNATKNIISERNLLENINYGLIVNLRYAFQDDENLFMVLDLMLGGDLRFHLDRMGKLPERFVRFYAAEISLSLNYLHKQHIIHRDLKPENILLDEKGHVHLSDLNIAVQLTSKKKSLTTIAGSLAYISPEILKKQGYSYSTDWWSLGVVIYELLYGKRPFKARTNEELQNLIMYGPIHYPNEPTVSPEAIDFMQSLLSRDISKRIGIGEAGFKQLKDHAWLKDACWDILSTKTVGAPFIPDEKKSNFDPTHELEEVFLEDNPLKVRRRTVKKSVSCEDMSALISTNEKHLLEQAFLNYDFTKPEEKDTSAMIIHSLKVVFNLITYREDCSSFCFFY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NRJ9</accession>
    <name>A0A1C7NRJ9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Gastricsin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">PGC_4</name>
        <name evidence="6" type="ORF">A0J61_00911</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase A1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000024">
        <property type="protein sequence ID" value="OBZ91046.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NRJ9"/>
    <dbReference type="STRING" id="101091.A0A1C7NRJ9"/>
    <dbReference type="InParanoid" id="A0A1C7NRJ9"/>
    <dbReference type="OrthoDB" id="2747330at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004190">
        <property type="term" value="F:aspartic-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05471">
        <property type="entry name" value="pepsin_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.70.10">
        <property type="entry name" value="Acid Proteases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001461">
        <property type="entry name" value="Aspartic_peptidase_A1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034164">
        <property type="entry name" value="Pepsin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033121">
        <property type="entry name" value="PEPTIDASE_A1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021109">
        <property type="entry name" value="Peptidase_aspartic_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47966">
        <property type="entry name" value="BETA-SITE APP-CLEAVING ENZYME, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47966:SF51">
        <property type="entry name" value="BETA-SITE APP-CLEAVING ENZYME, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00026">
        <property type="entry name" value="Asp"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00792">
        <property type="entry name" value="PEPSIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50630">
        <property type="entry name" value="Acid proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51767">
        <property type="entry name" value="PEPTIDASE_A1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008889864" evidence="4">
        <location>
            <begin position="27"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase A1" evidence="5">
        <location>
            <begin position="53"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="226"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="241"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="2">
        <location>
            <begin position="372"/>
            <end position="410"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR601461-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51767"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OBZ91046.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="462" mass="51761" checksum="9C5FCC1AE3FE5222" modified="2016-11-30" version="1">MKFSIVEIATITQLVLLSVSAHSVQKIPLYYQKRHHDHDFVTTGARELKNGMLGGLVEIGSPPQKFILAFDTSKGFTWVRTIDCKADNCQGRCSFNPGLSTTYRDAHQLFTMDYGKGIVNTSLFLDTFKFGDIKVNQMPIGGAYLMNNFDQGFDGFLGLGRSVNLSNVARYEKRSIPESGFVPIAYQQSSGVQSAQFGMYITHQSGPGFSENGSVFKEEMAYTTKSNVTQQSTLTHEKSKPSSLMSSHSTQDSKSTSKHQVTTPGGYGNLAKRHYHKEAPAGYLIIGGVDHDAIEGKLHHIPLNNECGNSQDWAVPVRDAGFENNFHIHKHAKAILSTSTDVIGLPNKQAEEFRKRWYATYDEPDNTFMVPCCLMDQLSSFRIQLGDIQVTLPPHYWSHFRQTDSCCEMCRTNIGKSESEKNFILGSSFTNAFYTQYDSEKEQISLALKKNHIDDDLEIYQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NRN5</accession>
    <name>A0A1C7NRN5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative arrestin-related trafficking adapter C2D10.04</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_00165</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000003">
        <property type="protein sequence ID" value="OBZ91785.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NRN5"/>
    <dbReference type="STRING" id="101091.A0A1C7NRN5"/>
    <dbReference type="InParanoid" id="A0A1C7NRN5"/>
    <dbReference type="OrthoDB" id="2333384at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030674">
        <property type="term" value="F:protein-macromolecule adaptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031625">
        <property type="term" value="F:ubiquitin protein ligase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070086">
        <property type="term" value="P:ubiquitin-dependent endocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.640">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014752">
        <property type="entry name" value="Arrestin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011021">
        <property type="entry name" value="Arrestin-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050357">
        <property type="entry name" value="Arrestin_domain-protein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11188">
        <property type="entry name" value="ARRESTIN DOMAIN CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11188:SF17">
        <property type="entry name" value="FI21816P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00339">
        <property type="entry name" value="Arrestin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="E set domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Arrestin-like N-terminal" evidence="1">
        <location>
            <begin position="28"/>
            <end position="136"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ91785.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="363" mass="41278" checksum="319765EC888893AE" modified="2016-11-30" version="1">MLSKSSHISLQLLEPTIYAEQQSDTCSVIRGTVNITLPKSITIRHISVHFSGKMEAKSHSLDYHKRKTVANEQLVLFDQTTAQSPLLLTMGTTPFGFEMQIPSGLPESIECSDVKVFYQVTAVMEYTTLHPVLRRPTKSKEETREDIRVARLPQKGILTGDTTNFIDSRTHQSTWLCYQLLVDKKAVALGSTLPITFRLLPTTESLSIDRITVQMLERRHLYRDTTHTTYSVCTMPPCCDMEQEKIPTQLPEVWEGTIYYRVPCGKTMVHSTRPYSEFHVDHCVLVSIGFSVPSLSNSRFGNTRVHKLITFKANIDVLDKVVGDMDSLELPSYDSPPPFEGYEQVIYGEYDRKFVEPPSYDEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NRR9</accession>
    <name>A0A1C7NRR9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">G1/S-specific cyclin pas1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">pas1_3</name>
        <name evidence="1" type="ORF">A0J61_00169</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000003">
        <property type="protein sequence ID" value="OBZ91793.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NRR9"/>
    <dbReference type="FunCoup" id="A0A1C7NRR9">
        <property type="interactions" value="5"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NRR9"/>
    <dbReference type="InParanoid" id="A0A1C7NRR9"/>
    <dbReference type="OrthoDB" id="286814at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000307">
        <property type="term" value="C:cyclin-dependent protein kinase holoenzyme complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016538">
        <property type="term" value="F:cyclin-dependent protein serine/threonine kinase regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019901">
        <property type="term" value="F:protein kinase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd20557">
        <property type="entry name" value="CYCLIN_ScPCL1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.10">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036915">
        <property type="entry name" value="Cyclin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013922">
        <property type="entry name" value="Cyclin_PHO80-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15615">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15615:SF36">
        <property type="entry name" value="PHO85 CYCLIN-5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08613">
        <property type="entry name" value="Cyclin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47954">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ91793.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="348" mass="39589" checksum="6D76320B397FF5CD" modified="2016-11-30" version="1">MDFRYHVDLHTLDNSLTPSKVFSTSLQTDPDLYALKNKKKNNGCRSNQLELKHLLKDTPIPHLVSTNRIAYVEALVDINAVVIESIWYPTTPYPQLKESRVSPVVPLRTFIQEVLKRSRTTYSTLQTALFYIFRVQPSIVQQLQQEGSWQHNAYISCGRRMFLASLVVASKFVQDKTYRNSAWAKIAGLPVQEINTAERYFLELINYQLYIDQPTFDHWHRLLHMRTQARMHHIPTSLYDLASCLSSFPSSLPSPPLSSLSYPPSPVCETPSSVNTCINSPGCHYACMCAQCSLKAPGLSLSLPSSISSSPAHTPIQVSPIRLHSSKKRKFEGKDHSLLDKKHCRFWQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NRX1</accession>
    <name>A0A1C7NRX1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Acyl-CoA dehydrogenase family member 11</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">Acad11</name>
        <name evidence="2" type="ORF">A0J61_00777</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000020">
        <property type="protein sequence ID" value="OBZ91156.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NRX1"/>
    <dbReference type="STRING" id="101091.A0A1C7NRX1"/>
    <dbReference type="InParanoid" id="A0A1C7NRX1"/>
    <dbReference type="OrthoDB" id="191037at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004672">
        <property type="term" value="F:protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05154">
        <property type="entry name" value="ACAD10_11_N-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1200.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052898">
        <property type="entry name" value="ACAD10-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041726">
        <property type="entry name" value="ACAD10_11_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002575">
        <property type="entry name" value="Aminoglycoside_PTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47829:SF3">
        <property type="entry name" value="AMINOGLYCOSIDE PHOSPHOTRANSFERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47829">
        <property type="entry name" value="HYDROLASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G12880)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01636">
        <property type="entry name" value="APH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aminoglycoside phosphotransferase" evidence="1">
        <location>
            <begin position="38"/>
            <end position="275"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ91156.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="354" mass="40233" checksum="8C40CDC77AC2C221" modified="2016-11-30" version="1">MTENQATSQVRQGHELDNGKLEAYLLQHIPQFKAPLHISQFQFGQSNPTYLLKDGNQQQYVLRKKPPGALLSSTAHAVEREYRIIQALGTQTNVPVPKVYVLCEDNSIIGTPFYVMEFLKGRIFEDCRMLSLPFEERRQLWHAAVKTLAHLHAVDFKAIGLESYGRHHGFYDRQMKSLSKVSQAQAQTQDEETGQSVGPIPRLDAMFSWFKRNQAKDQATLVHGDFKIDNLMFHPTEARVIGILDWELSTIGHPLSDLSNLLQPYYIPLSEEKNAGLLGFKGLSKESLPVPDVEELIQVYCQETRQPYPIDRWMFVVAFSFFRLAVISQGIAARVARKQASSAKAKIYAARFIP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NS93</accession>
    <name>A0A1C7NS93_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">FAR1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_00626</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000015">
        <property type="protein sequence ID" value="OBZ91296.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NS93"/>
    <dbReference type="InParanoid" id="A0A1C7NS93"/>
    <dbReference type="OrthoDB" id="4815524at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004330">
        <property type="entry name" value="FAR1_DNA_bnd_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47718">
        <property type="entry name" value="OS01G0519700 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47718:SF3">
        <property type="entry name" value="PROTEIN FAR1-RELATED SEQUENCE 5-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03101">
        <property type="entry name" value="FAR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAR1" evidence="1">
        <location>
            <begin position="25"/>
            <end position="104"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03101"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ91296.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="151" mass="17243" checksum="3A13EBE93DD37A22" modified="2016-11-30" version="1">MHPYTFTPSIGSKFMNLEEATKKCKEHAESQGFNISIAKSSTNPVAKRRYYCELKCSRAGTYRSKSTGQRRSSHKRCGCKYRIRMKEMGQEWIITHFGSIHNHEHLIQNDQNSEADGHDIREIDLEVSASLHKLQCALQASTDRNVKASVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NSX0</accession>
    <name>A0A1C7NSX0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Geranylgeranyl transferase type-1 subunit beta</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">Geranylgeranyl transferase type I subunit beta</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="13">Type I protein geranyl-geranyltransferase subunit beta</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="15" type="primary">PGGT1B</name>
        <name evidence="15" type="ORF">A0J61_01347</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="12">Heterodimer of FNTA and PGGT1B. PGGT1B mediates interaction with substrate peptides.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the protein prenyltransferase subunit beta family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000041">
        <property type="protein sequence ID" value="OBZ90604.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NSX0"/>
    <dbReference type="FunCoup" id="A0A1C7NSX0">
        <property type="interactions" value="310"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NSX0"/>
    <dbReference type="InParanoid" id="A0A1C7NSX0"/>
    <dbReference type="OrthoDB" id="24893at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005953">
        <property type="term" value="C:CAAX-protein geranylgeranyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004662">
        <property type="term" value="F:CAAX-protein geranylgeranyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="1.50.10.20:FF:000005">
        <property type="entry name" value="Geranylgeranyl transferase type-1 subunit beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045089">
        <property type="entry name" value="PGGT1B-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001330">
        <property type="entry name" value="Prenyltrans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008930">
        <property type="entry name" value="Terpenoid_cyclase/PrenylTrfase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11774">
        <property type="entry name" value="GERANYLGERANYL TRANSFERASE TYPE BETA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11774:SF4">
        <property type="entry name" value="GERANYLGERANYL TRANSFERASE TYPE-1 SUBUNIT BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00432">
        <property type="entry name" value="Prenyltrans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48239">
        <property type="entry name" value="Terpenoid cyclases/Protein prenyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0637">Prenyltransferase</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0677">Repeat</keyword>
    <keyword evidence="6 15" id="KW-0808">Transferase</keyword>
    <keyword evidence="9" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Prenyltransferase alpha-alpha toroid" evidence="14">
        <location>
            <begin position="5"/>
            <end position="334"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010497"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00020603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022602"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00031713"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00065714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00078363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF00432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="OBZ90604.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="352" mass="39392" checksum="DCB1DE1E19A4B4FD" modified="2016-11-30" version="1">MTKEFNREKHIRYFKSNLSMLPTPYTQTETNRMTLAFFALGGLSLLGELDSNVSAENKKDWIEWIYAQQVLPTGQDPDPNEAMCGFRGSSWSGRPFNPHTTTLEFQHYDSSHIANTYTALLNLLLLGDDLSRVNRKAIIHTLSLLQSDDGSIAPTSGSLERDARFVFCACAISYILNDWSGLDVEKSVLWIRRLQSYEHGIAQCPNEEAHGGSTFCGVAALCLMNKMEEGIVDKEGMIQWCLSRQITGFQGRPNKLPDACYCFWIGAALKMLGGYELINHEVMKTFLFDCQPKMGGFGKDPESFPDLLHSYMGIAALSLSEESGIQSIEPSLNVPASAYQHLKENTVFWKGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NVR8</accession>
    <name>A0A1C7NVR8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">LysM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">A0J61_00382</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000008">
        <property type="protein sequence ID" value="OBZ91564.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NVR8"/>
    <dbReference type="STRING" id="101091.A0A1C7NVR8"/>
    <dbReference type="InParanoid" id="A0A1C7NVR8"/>
    <dbReference type="OrthoDB" id="3044029at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008061">
        <property type="term" value="F:chitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00118">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.350.10">
        <property type="entry name" value="LysM domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018392">
        <property type="entry name" value="LysM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052210">
        <property type="entry name" value="LysM1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036779">
        <property type="entry name" value="LysM_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34997">
        <property type="entry name" value="AM15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34997:SF1">
        <property type="entry name" value="PEPTIDOGLYCAN-BINDING LYSIN DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01476">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00257">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54106">
        <property type="entry name" value="LysM domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51782">
        <property type="entry name" value="LYSM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0147">Chitin-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0843">Virulence</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008889957" description="LysM domain-containing protein" evidence="3">
        <location>
            <begin position="21"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="domain" description="LysM" evidence="4">
        <location>
            <begin position="26"/>
            <end position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022669"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OBZ91564.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="284" mass="29821" checksum="6D841EDA40D7AFE8" modified="2016-11-30" version="1">MRSPFTLAVACLAAIMAVEAAPACSKTYTVVAGDTCALAAQKSGTTISKLKSLNTSINSKCSNLRIGQKLCVATGSTTTKKVTSKKAATTKKAAATKKATTTKKAATTTSTQTSSASPTHDIANYGLTIQITSKTDFCMMLPSSPGNKAANGGKIDIDAIANSEKNAIAFCTKPSANAPGASTMPVTLLKSAYFYKNTTAEYVQVTGKLNPAAYELSTKDNGGQYDNHGAGSPPNSICYGYRYYVAMVEPNNPDYCVRCCNHYEDCNAGRSEYGCKRVVSNGTY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MTF8</accession>
    <name>A0A1C7MTF8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Cation/H(+) antiporter 19</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">CHX19</name>
        <name evidence="9" type="ORF">A0J61_11809</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01002523">
        <property type="protein sequence ID" value="OBZ80142.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MTF8"/>
    <dbReference type="STRING" id="101091.A0A1C7MTF8"/>
    <dbReference type="InParanoid" id="A0A1C7MTF8"/>
    <dbReference type="OrthoDB" id="2687058at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015297">
        <property type="term" value="F:antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902600">
        <property type="term" value="P:proton transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1530.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006153">
        <property type="entry name" value="Cation/H_exchanger_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050794">
        <property type="entry name" value="CPA2_transporter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038770">
        <property type="entry name" value="Na+/solute_symporter_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32468">
        <property type="entry name" value="CATION/H + ANTIPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32468:SF0">
        <property type="entry name" value="K(+)_H(+) ANTIPORTER 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00999">
        <property type="entry name" value="Na_H_Exchanger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0406">Ion transport</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="31"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="58"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="92"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="123"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="domain" description="Cation/H+ exchanger transmembrane" evidence="8">
        <location>
            <begin position="1"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="302"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00999"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OBZ80142.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="302" mass="33102" checksum="BEE07232B942C0DD" modified="2016-11-30" version="1" fragment="single">VHAIFGGFLAGVIVPHDHGLAVKITEKIEDIVNIVFLPLYFTLSGLKTQIGLLDSGAVWGYVILVIVLACFGKIIGCAGAAKISGMTTRESFTVGFLMSCKGLVELIVLNIGHDAGVLNDQVFVIMVVMALVTTFMTTPVVMWLYPESYQKATAMRSDTDNLSVAKDISRINSRMDFGQSFSLVTMVNRIESAISIMSIIRMLKREPADPSAKIGRYQLNVHAMRLLELTQRASDVMKLKDMEETSRQDPVLSVLRTFTSLSGGIEMLGTHLDFQTRSKFVNTIANYSQTVSADMVLIPVAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MUC8</accession>
    <name>A0A1C7MUC8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Chromatin-remodeling complexes subunit ngg1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">ngg1</name>
        <name evidence="7" type="ORF">A0J61_11539</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the NGG1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01002164">
        <property type="protein sequence ID" value="OBZ80412.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MUC8"/>
    <dbReference type="STRING" id="101091.A0A1C7MUC8"/>
    <dbReference type="InParanoid" id="A0A1C7MUC8"/>
    <dbReference type="OrthoDB" id="1232at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000124">
        <property type="term" value="C:SAGA complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003713">
        <property type="term" value="F:transcription coactivator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019340">
        <property type="entry name" value="Histone_AcTrfase_su3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13556:SF2">
        <property type="entry name" value="TRANSCRIPTIONAL ADAPTER 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13556">
        <property type="entry name" value="TRANSCRIPTIONAL ADAPTER 3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="100"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="134"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="376"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005330"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OBZ80412.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="376" mass="43239" checksum="175D3442B8E5E709" modified="2016-11-30" version="1" fragment="single">MEAARRYELPKTLSPSTSSIIDQHRYNLLHSNGQHQEAIPEASDLLSIKADLESLLPSAERRNKDLKFGLGTIDHKSREMESTSGKSVNAMIEKMRIKQELEDDSDTHQNNTLSRNELSRQAALEQIKKKRRRESTDESIHRRSESPHLVKLKKLEGIPSLVSRSESPPASKPPKSNHDLKKAKKSAGRPQQQASESEDIDFVRVKPKDQVQIATFWAALEPYFRNLTEDDRQILLQKADQGKPYLIPPLGQHYLEKWTEEDQQTMQDVELLQPQLQQHKLKYLQSQQSLTDQHLMYDDLGCGTLTERLISSLVTENIINSDTEDYKSMCESDREDDYDAYENHGVDHKRHNAKAILLSEPPEEVAGFEERLKREL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MUD5</accession>
    <name>A0A1C7MUD5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Peptidyl-prolyl cis-trans isomerase</fullName>
            <shortName evidence="4">PPIase</shortName>
            <ecNumber evidence="4">5.2.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">cyp7</name>
        <name evidence="6" type="ORF">A0J61_11445</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 4">
            <text>[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)</text>
            <dbReference type="Rhea" id="RHEA:16237"/>
            <dbReference type="Rhea" id="RHEA-COMP:10747"/>
            <dbReference type="Rhea" id="RHEA-COMP:10748"/>
            <dbReference type="ChEBI" id="CHEBI:83833"/>
            <dbReference type="ChEBI" id="CHEBI:83834"/>
            <dbReference type="EC" id="5.2.1.8"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the cyclophilin-type PPIase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.2.1.8" evidence="4"/>
    <dbReference type="EMBL" id="LUGH01002040">
        <property type="protein sequence ID" value="OBZ80505.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MUD5"/>
    <dbReference type="STRING" id="101091.A0A1C7MUD5"/>
    <dbReference type="InParanoid" id="A0A1C7MUD5"/>
    <dbReference type="OrthoDB" id="193499at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016018">
        <property type="term" value="F:cyclosporin A binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.100.10:FF:000025">
        <property type="entry name" value="Peptidyl-prolyl cis-trans isomerase CYP19-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.100.10">
        <property type="entry name" value="Cyclophilin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029000">
        <property type="entry name" value="Cyclophilin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024936">
        <property type="entry name" value="Cyclophilin-type_PPIase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020892">
        <property type="entry name" value="Cyclophilin-type_PPIase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002130">
        <property type="entry name" value="Cyclophilin-type_PPIase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11071">
        <property type="entry name" value="PEPTIDYL-PROLYL CIS-TRANS ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11071:SF561">
        <property type="entry name" value="PEPTIDYL-PROLYL CIS-TRANS ISOMERASE D-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00160">
        <property type="entry name" value="Pro_isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001467">
        <property type="entry name" value="Peptidylpro_ismrse"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00153">
        <property type="entry name" value="CSAPPISMRASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50891">
        <property type="entry name" value="Cyclophilin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00170">
        <property type="entry name" value="CSA_PPIASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50072">
        <property type="entry name" value="CSA_PPIASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4 6" id="KW-0413">Isomerase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0697">Rotamase</keyword>
    <feature type="domain" description="PPIase cyclophilin-type" evidence="5">
        <location>
            <begin position="30"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OBZ80505.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="141" mass="15697" checksum="1FCE0099E3749252" modified="2016-11-30" version="1" fragment="single">MDKKELWNLHGCTNSSVRSIGSQVERPIVFFDISIGDVPVGRMKMELFSDIVPKTAENFRQLCTGEHRRNGQPQGFKNCLFHRVIKDFMVQGGDFLKGDGTGSMSIYGDKFPDENFIEKHSGAGLLSMANSGPNTNGCQFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MUM4</accession>
    <name>A0A1C7MUM4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_11398</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001988">
        <property type="protein sequence ID" value="OBZ80553.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MUM4"/>
    <dbReference type="STRING" id="101091.A0A1C7MUM4"/>
    <dbReference type="InParanoid" id="A0A1C7MUM4"/>
    <dbReference type="OrthoDB" id="2281765at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="170"/>
            <end position="204"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ80553.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="204" mass="22924" checksum="6C6E32E33387D54A" modified="2016-11-30" version="1">MQRIPRPVRITPAARDAAARTFLPVSGSQGFSFMYLPCRSKEPISAMREKLRKLKLQSSRLLDIHYPTNNVMAMLVHNDYLEEATNLLQLNKIDLIENFSPDSPNNLSNPKLADLTHEERIATAINLHQTRLTNIALRIRQDQRKLAVARAFHKQAWITTEQFVSLVQTVRPSTQPPAPSTSTNMQIDSSDDSPADGSTLAHSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MV09</accession>
    <name>A0A1C7MV09_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">CCHC-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">A0J61_11216</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001786">
        <property type="protein sequence ID" value="OBZ80735.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="InParanoid" id="A0A1C7MV09"/>
    <dbReference type="OrthoDB" id="2290252at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004190">
        <property type="term" value="F:aspartic-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00303">
        <property type="entry name" value="retropepsin_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.70.10">
        <property type="entry name" value="Acid Proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001969">
        <property type="entry name" value="Aspartic_peptidase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021109">
        <property type="entry name" value="Peptidase_aspartic_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001878">
        <property type="entry name" value="Znf_CCHC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036875">
        <property type="entry name" value="Znf_CCHC_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46888:SF1">
        <property type="entry name" value="RIBONUCLEASE H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46888">
        <property type="entry name" value="ZINC KNUCKLE DOMAINCONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13650">
        <property type="entry name" value="Asp_protease_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50630">
        <property type="entry name" value="Acid proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57756">
        <property type="entry name" value="Retrovirus zinc finger-like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00141">
        <property type="entry name" value="ASP_PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50158">
        <property type="entry name" value="ZF_CCHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0064">Aspartyl protease</keyword>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1" id="KW-0645">Protease</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <keyword evidence="2" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="CCHC-type" evidence="4">
        <location>
            <begin position="244"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="189"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="197"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="398"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022750"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OBZ80735.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="398" mass="43693" checksum="644D771731BD5A83" modified="2016-11-30" version="1" fragment="single">RLGHTPICPPFDPKENINNWLNHFELKPQRLSLTDEQKRLHIXSYLPAEIAHWAARSPEVQTWPTLKAKLLKTYGIPASKQKAITCRRLESLRQGNLSSRRFAILFDSVVLEFPQDSALDDHILRMIYLKCMSPKIRSIILLNIITTTTWQLINKAAVALEESLSSDDTLLEDAFAQLSLGPPLVSAPVGSSLHQTRSSGSRFGSASSFASGSGPRSSGASRNQPRRQQRDPMRLWSDSSKPICGHCKKEGHLAKKCRSRHNISQMDASPMSPNIHQAESVCYLQPTNNNSYAAIPLDDGPVEATINNIVVISPSISLTNTVTTPRIRLTVQGHLVNALVDTGASIFAVRASLVNKLHLTPDSTKAMSFTDVDNRSTTSLGTVSLTCMIGNVSVTLNC</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-06-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MVY7</accession>
    <name>A0A1C7MVY7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_10967</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001547">
        <property type="protein sequence ID" value="OBZ80983.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MVY7"/>
    <dbReference type="InParanoid" id="A0A1C7MVY7"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="77"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="134"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="165"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ80983.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="165" mass="18371" checksum="5810B4B150CAA4D1" modified="2016-11-30" version="1" fragment="single">MQRHLTKKASDAHRITNAPGSHRAPVANNVDYSYDEFPLLPPASSRHNPIAATNIRNSGNPIGQEKPSESMDIDNLTGNALSSNDVAGRTSPPSVEDELFEDLGNDDLITEKSFRETISDLKKKLAKLSFVLAYAKKSSDIDRLRAEKDFVKQRYLQALEDFKDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MW40</accession>
    <name>A0A1C7MW40_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Retrotransposon gag domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">A0J61_10846</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001439">
        <property type="protein sequence ID" value="OBZ81105.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MW40"/>
    <dbReference type="STRING" id="101091.A0A1C7MW40"/>
    <dbReference type="InParanoid" id="A0A1C7MW40"/>
    <dbReference type="OrthoDB" id="2290219at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004190">
        <property type="term" value="F:aspartic-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00303">
        <property type="entry name" value="retropepsin_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.70.10">
        <property type="entry name" value="Acid Proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001969">
        <property type="entry name" value="Aspartic_peptidase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021109">
        <property type="entry name" value="Peptidase_aspartic_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005162">
        <property type="entry name" value="Retrotrans_gag_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33223">
        <property type="entry name" value="CCHC-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33223:SF6">
        <property type="entry name" value="CCHC-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13650">
        <property type="entry name" value="Asp_protease_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03732">
        <property type="entry name" value="Retrotrans_gag"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50630">
        <property type="entry name" value="Acid proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00141">
        <property type="entry name" value="ASP_PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0064">Aspartyl protease</keyword>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0645">Protease</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Retrotransposon gag" evidence="3">
        <location>
            <begin position="79"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="243"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="299"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="244"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="315"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="560"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022750"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF03732"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OBZ81105.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="560" mass="62758" checksum="2E76943947746DDD" modified="2016-11-30" version="1" fragment="single">MTDNNLDQQAETFMQLCATIHKKFSNLPDSTNRQYQVQLQKPDAFTGESFSQTVVDSWIRSVERHQAFYKWNNEQTVLFAVSFLESHADNWYRCLKAGPDQPTTLPDFKDRFLSAFRPGNAYDIARNRLDQLRHTGTIQQYVNEFRAICLLVLDLNGLEAFDRFMRGFKLGYDHLFAELRAVPTEMRSLDLAFQKALTFEASHVRRAAQGQVVAPTTFLSPAVPYADRDDPMVLDALQSRSYANSHKSGNNSNNYKGSTSGQGSRNYGNGNIVCYFCGKSGHIKSKYHRRRAAIQAIDREAGGPQSNQYRHHTNNQHSSLNNMDTHTPSTDDQNNKDTSLTQYPSKVSNIKNEFYSSERLANESSQLPSSDDKLPMELVPVMSTQVSELHYVAKLNTLSSSLPLYDGIAGNNNTVVSVLIDSGASDNYVSSRLVNAIAPDVTPTPAREVETADGALTVIDKQARIDINLGGYLFDVNAFVFPSKFDLILGRSWLKAHCPSPDWTNDTWYLRVGNDAVRLIPSGRSGLFDDDSTLVAEGQRPQLNFLISQKQVESCLRDDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MWH3</accession>
    <name>A0A1C7MWH3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_11172</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001738">
        <property type="protein sequence ID" value="OBZ80779.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MWH3"/>
    <dbReference type="STRING" id="101091.A0A1C7MWH3"/>
    <dbReference type="InParanoid" id="A0A1C7MWH3"/>
    <dbReference type="OrthoDB" id="2290422at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="40"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="40"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="69"/>
            <end position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ80779.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="126" mass="14363" checksum="939DB3DF461D04F2" modified="2016-11-30" version="1">MVCQGASIERIFIFHTIAFVFFLYQTGRLRLVLRRAVAPQNNNFNHNNQAPNQQGNNQPNRNQQEDNGDATTQNRQTENIPPARPTTSLDVWRRGAYTFAASLWPTYGVDPRIAQAFENNNEQAEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MXB9</accession>
    <name>A0A1C7MXB9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="9">GTP-binding protein ypt3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">ypt3</name>
        <name evidence="9" type="ORF">A0J61_10499</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Golgi apparatus membrane</location>
            <topology evidence="7">Lipid-anchor</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the small GTPase superfamily. Rab family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001202">
        <property type="protein sequence ID" value="OBZ81453.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MXB9"/>
    <dbReference type="STRING" id="101091.A0A1C7MXB9"/>
    <dbReference type="InParanoid" id="A0A1C7MXB9"/>
    <dbReference type="OrthoDB" id="9989112at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016197">
        <property type="term" value="P:endosomal transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006887">
        <property type="term" value="P:exocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000067">
        <property type="entry name" value="ras-related protein RABA1f"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050209">
        <property type="entry name" value="Rab_GTPases_membrane_traffic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001806">
        <property type="entry name" value="Small_GTPase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47979">
        <property type="entry name" value="DRAB11-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00071">
        <property type="entry name" value="Ras"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00449">
        <property type="entry name" value="RASTRNSFRMNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00175">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00176">
        <property type="entry name" value="RAN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00173">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00174">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51419">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51421">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51420">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="5" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-0636">Prenylation</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="202"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="206"/>
            <end position="223"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023289"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00037794"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OBZ81453.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="223" mass="25065" checksum="CFA0FF4C13677181" modified="2016-11-30" version="1">MISEDAYDYLFKIVIIGDSGVGKSNLLLRYTSDEFMEDSRSTIGVEFATKSLKINDSFVKAQIWDTSGQERYKAITSAFYRGAVGALLVYDVTRKSSFEHVNQWLKELKEHTEETIPLVLIGNKLDLANTNRAVLTETAKQFATDANMLFFETSAYDATNVTMAFETMFDHVYQELSKSKLLKKNSSANLAVNASETVTLQPPSKEYNRRKSGENKKEEGGCC</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MXH7</accession>
    <name>A0A1C7MXH7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transposon TX1 uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">YTX2_13</name>
        <name evidence="2" type="ORF">A0J61_10347</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001128">
        <property type="protein sequence ID" value="OBZ81605.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MXH7"/>
    <dbReference type="InParanoid" id="A0A1C7MXH7"/>
    <dbReference type="OrthoDB" id="2281256at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01650">
        <property type="entry name" value="RT_nLTR_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.10.10">
        <property type="entry name" value="Endonuclease/exonuclease/phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036691">
        <property type="entry name" value="Endo/exonu/phosph_ase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000477">
        <property type="entry name" value="RT_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19446">
        <property type="entry name" value="REVERSE TRANSCRIPTASES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00078">
        <property type="entry name" value="RVT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56219">
        <property type="entry name" value="DNase I-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50878">
        <property type="entry name" value="RT_POL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Reverse transcriptase" evidence="1">
        <location>
            <begin position="468"/>
            <end position="745"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ81605.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="1053" mass="119193" checksum="3D03A0154283EDC4" modified="2016-11-30" version="1">MSRSTIRIGSLNAPSIFKESHPELRKSFLTHLKSHSLSLGILCLQDVLSVQALSFTDTHQHEFRTYLFPNTSSHVTWRTVIICLNPTLTIKDFLTYLDGRCTFVSIVDALDRTVCSNLNFYIPPALGERILFFDSLRIEVPFFSLTHAATITSFILGNFNSNLKDLSFQNHVFVEPWMEWLNAHYTNCFPEALPTYTSAANHNTRKTIDYVFVDKPWMWIPSLHPRFIQLLTASENTFINQIDFEALHISVTSLPSTPPVLFVASNATKRHRVWESFKLLLQNVAKSYSRHSKARYQHILSRLQLERNDLLVSVSSAESYNGVYLPRLQQLDTAIEAVVDKETAQYSLRTATRWRGQGERNNKYFFRTSKHRQRQQTIQSLTDSNTGASITTTSGMLREARSFYTALYTPDPIDQSAVNELPDSIPQSVVLSDEDQHMLLDLFVDDDLLASFKHSPTGKSPGLDSILCDALQFSYTSSWNFTRMVLLFKKGDPTLLQNWRPLSLINVDAKIFMKLLANRFNLVLSELINPHQTGFMPNRLISDNGWLNHTLMATLRASKSLSPQVAVLLDTEKAYDRFHPGYLQQIQITVNGWLSAPVSQSKGLRQCDPLSPLLFNLAYEPLLRYILASSAFKGVGVPQLYPSKPLPCSPLDLHSRVRASPPVRLLAYADDLEIFLSSLSKWPSLLEVLVLYSRASDARTNISKTTVVSLNGAPSPEWSDLCHSVGFAWHDATSTDAVKLLGYSLYSSDVQLTRFLSRIRSKLFGHIHHIRLRGLSVRGLSVVVNSLAISRPRRQGGMSIVNIQDQASALQFICLKRLAADPEDDDFLTPWLLRFFQINTGHASVLPVLLKPSIFKHFFKFCPPMLQPLKLVGRLPALDLCESWSLPWLLDLHLSLVVTMHPTCLLPLPRIPNHYLVSDLLRFDNQMDILGASRAFIRSSRCSLLHLFDAIFLPSPTDTVACVLHPLIRNWCRLLPLSSDVPVASPFPTDSNTYLPSMSDWLIDVERRGPIAVFDVRLSQLRRWWAKDRQVLEIVSVATPPTSRFHALVAAFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MXI6</accession>
    <name>A0A1C7MXI6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">YAP binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_10420</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001164">
        <property type="protein sequence ID" value="OBZ81530.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MXI6"/>
    <dbReference type="STRING" id="101091.A0A1C7MXI6"/>
    <dbReference type="InParanoid" id="A0A1C7MXI6"/>
    <dbReference type="OrthoDB" id="10006572at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.50.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041086">
        <property type="entry name" value="YBD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17725">
        <property type="entry name" value="YBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="YAP binding" evidence="1">
        <location>
            <begin position="179"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF17725"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ81530.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="341" mass="38957" checksum="0C7287DE3CF60B0C" modified="2016-11-30" version="1" fragment="single">SSDESSINSSPSPTDYVFDIMCNDPAQQQALSMLQFKDFYDPFQQSPYHHTSLNPTLNLVDHTNLMTDSFFGSQPSNEWIHPGFLPTHVSPQLDNDRLEASVPSSNDMLINSLTILTQPKTRQKPTERVDHALWPNYLCLYLEYTLPYDPACRLLSHNLSHLAHCHPKLAKSSSDLISKEKCPSISTLTPNSDRYALLLAKTKLDLNLSISDFAFNNTAFFETQTRRTIECTTTIYSFGHVVLESKETQQAFWVTEDKYMYNFVFVNQFFDAFMKGIRSLQSWDEVDIAINNLCIVQSFHDVESKGTNESSEETLPLLVMVYEFERGDGTIDITQIEEKLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MXN5</accession>
    <name>A0A1C7MXN5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">ATP synthase subunit 5, mitochondrial</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">atp-5</name>
        <name evidence="10" type="ORF">A0J61_10286</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ATPase delta chain family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001103">
        <property type="protein sequence ID" value="OBZ81665.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MXN5"/>
    <dbReference type="FunCoup" id="A0A1C7MXN5">
        <property type="interactions" value="348"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7MXN5"/>
    <dbReference type="InParanoid" id="A0A1C7MXN5"/>
    <dbReference type="OrthoDB" id="1262810at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046933">
        <property type="term" value="F:proton-transporting ATP synthase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.520.20">
        <property type="entry name" value="N-terminal domain of the delta subunit of the F1F0-ATP synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01416">
        <property type="entry name" value="ATP_synth_delta_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026015">
        <property type="entry name" value="ATP_synth_OSCP/delta_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020781">
        <property type="entry name" value="ATPase_OSCP/d_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000711">
        <property type="entry name" value="ATPase_OSCP/dsu"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01145">
        <property type="entry name" value="ATP_synt_delta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11910">
        <property type="entry name" value="ATP SYNTHASE DELTA CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00213">
        <property type="entry name" value="OSCP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00125">
        <property type="entry name" value="ATPASEDELTA"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47928">
        <property type="entry name" value="N-terminal domain of the delta subunit of the F1F0-ATP synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00389">
        <property type="entry name" value="ATPASE_DELTA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0066">ATP synthesis</keyword>
    <keyword evidence="9" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="6" id="KW-0406">Ion transport</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="coiled-coil region" evidence="9">
        <location>
            <begin position="77"/>
            <end position="104"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007046"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00014723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023310"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OBZ81665.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="245" mass="26903" checksum="74C147938F6C17AF" modified="2016-11-30" version="1">MASRFTRLTTAVPKVKSYTPQHMTTTGYDMWKIDLTIIYFFFLFKLARGYAAAPTSVKAPITLFGLDGRYATALYTAAARQNVLEAVEKDLKTLNQAVEKDESLKAFLENPTIHRGAKMQGINDILKKAGKPSQITQNFFETLAENGRLNQTSKVVEAFSELMSAHRNELPLVVTSAKALDKAALNKVVESLQKSNLAEGKKLLVSNKVKPDILGGLLVEIGDKSIDLTVASKLAKLNKLITDSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MXR3</accession>
    <name>A0A1C7MXR3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">U3 small nucleolar ribonucleoprotein protein IMP3</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">U3 small nucleolar ribonucleoprotein protein imp3</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="primary">IMP3</name>
        <name evidence="13" type="ORF">A0J61_10328</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the universal ribosomal protein uS4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001120">
        <property type="protein sequence ID" value="OBZ81623.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MXR3"/>
    <dbReference type="FunCoup" id="A0A1C7MXR3">
        <property type="interactions" value="229"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7MXR3"/>
    <dbReference type="InParanoid" id="A0A1C7MXR3"/>
    <dbReference type="OrthoDB" id="10248812at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034457">
        <property type="term" value="C:Mpp10 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032040">
        <property type="term" value="C:small-subunit processome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140691">
        <property type="term" value="F:RNA folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030515">
        <property type="term" value="F:snoRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042274">
        <property type="term" value="P:ribosomal small subunit biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd00165">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.290.10:FF:000006">
        <property type="entry name" value="U3 small nucleolar ribonucleoprotein IMP3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.290.10">
        <property type="entry name" value="RNA-binding S4 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022801">
        <property type="entry name" value="Ribosomal_uS4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001912">
        <property type="entry name" value="Ribosomal_uS4_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002942">
        <property type="entry name" value="S4_RNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036986">
        <property type="entry name" value="S4_RNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11831">
        <property type="entry name" value="30S 40S RIBOSOMAL PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11831:SF1">
        <property type="entry name" value="U3 SMALL NUCLEOLAR RIBONUCLEOPROTEIN PROTEIN IMP3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00163">
        <property type="entry name" value="Ribosomal_S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01479">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01390">
        <property type="entry name" value="Ribosomal_S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00363">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55174">
        <property type="entry name" value="Alpha-L RNA-binding motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50889">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 13" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="5 10" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4" id="KW-0699">rRNA-binding</keyword>
    <feature type="domain" description="Small ribosomal subunit protein uS4 N-terminal" evidence="12">
        <location>
            <begin position="3"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="domain" description="RNA-binding S4" evidence="11">
        <location>
            <begin position="107"/>
            <end position="172"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007465"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00069727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00072223"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00182"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM00363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM01390"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="OBZ81623.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="181" mass="21609" checksum="BE0702D4DD69D33A" modified="2016-11-30" version="1">MRQLKHHEQKLLKKVDFLQWKKEDSLREIKVIRRYFLQQREDYHKYNKLVGNIRALANKISLLDARDPFRNQQEKALLEKLYNMGIITATTKFSDCRKVTVSAFCRRRLPIVMCRLKMAETVKEAVTFVEQGHIRVGPQTITDPAFLVNRTMEDYVTWVDTSKIKRKIMKYNDKLDDFDLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MYX4</accession>
    <name>A0A1C7MYX4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">A0J61_09984</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000993">
        <property type="protein sequence ID" value="OBZ81968.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MYX4"/>
    <dbReference type="STRING" id="101091.A0A1C7MYX4"/>
    <dbReference type="InParanoid" id="A0A1C7MYX4"/>
    <dbReference type="OrthoDB" id="1882547at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006004">
        <property type="term" value="P:fucose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd11296">
        <property type="entry name" value="O-FucT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11350">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019378">
        <property type="entry name" value="GDP-Fuc_O-FucTrfase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36050">
        <property type="entry name" value="O-FUCOSYLTRANSFERASE 30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36050:SF1">
        <property type="entry name" value="O-FUCOSYLTRANSFERASE 30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10250">
        <property type="entry name" value="O-FucT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="2" id="KW-0294">Fucose metabolism</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023253"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OBZ81968.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="426" mass="49313" checksum="68AA8E2CB392D9A5" modified="2016-11-30" version="1">MTKRNLPFPFNQTFSTRSAVFSKSVQFDFRPSPPIDPHEKYLTFFTHSGFQNQLIQVENGILLAWYLNRTLILPKAILGDVFGWNQFNKLLHHHTVRDTNSYFCSQFTDRRLRKKMPCPDPSRYAVASFDELIDLSWARQHVKIVEREQSDFYWLQRQFGIKKDPFLLDDPDVGTFVNGDILFFKDKTRYDWRIYDVPAKHRFLGRYVDSLDVAQLHNRTERLIHFTSLFGTGKFAIKDPNNKAFFASLRNSMVYKHPAVLKAAESALEALGGSGHFIGAHLRTADGLFIKAISENIEHILHHIQAPTPPVNNNGSMSLTECVHLAKTNQTALVFLATDAMQPRNDDRFKPLWQHLPCTFTINDILHKDHSVWRYMNQYRTKHTRQSMHKYLMPLIDALVASKGSSFVGTKGSTFSGYIKRLHQNH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MZ14</accession>
    <name>A0A1C7MZ14_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 12">T-complex protein 1 subunit delta</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">cct4</name>
        <name evidence="14" type="ORF">A0J61_09895</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Molecular chaperone; assists the folding of proteins upon ATP hydrolysis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Component of the T-complex protein 1 (TCP1) complex.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Heterooligomeric complex of about 850 to 900 kDa that forms two stacked rings, 12 to 16 nm in diameter.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 11">Belongs to the TCP-1 chaperonin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000966">
        <property type="protein sequence ID" value="OBZ82057.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MZ14"/>
    <dbReference type="FunCoup" id="A0A1C7MZ14">
        <property type="interactions" value="884"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7MZ14"/>
    <dbReference type="InParanoid" id="A0A1C7MZ14"/>
    <dbReference type="OrthoDB" id="10248520at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005832">
        <property type="term" value="C:chaperonin-containing T-complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03338">
        <property type="entry name" value="TCP1_delta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.50.7.10:FF:000010">
        <property type="entry name" value="T-complex protein 1 subunit delta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.7.10">
        <property type="entry name" value="GroEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.560.10">
        <property type="entry name" value="GroEL-like equatorial domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.260.10">
        <property type="entry name" value="TCP-1-like chaperonin intermediate domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012717">
        <property type="entry name" value="Chap_CCT_delta"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017998">
        <property type="entry name" value="Chaperone_TCP-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002194">
        <property type="entry name" value="Chaperonin_TCP-1_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002423">
        <property type="entry name" value="Cpn60/GroEL/TCP-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027409">
        <property type="entry name" value="GroEL-like_apical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027413">
        <property type="entry name" value="GROEL-like_equatorial_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027410">
        <property type="entry name" value="TCP-1-like_intermed_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053374">
        <property type="entry name" value="TCP-1_chaperonin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054827">
        <property type="entry name" value="thermosome_alpha"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02342">
        <property type="entry name" value="chap_CCT_delta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF041082">
        <property type="entry name" value="thermosome_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF041083">
        <property type="entry name" value="thermosome_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11353">
        <property type="entry name" value="CHAPERONIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00118">
        <property type="entry name" value="Cpn60_TCP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00304">
        <property type="entry name" value="TCOMPLEXTCP1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52029">
        <property type="entry name" value="GroEL apical domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48592">
        <property type="entry name" value="GroEL equatorial domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54849">
        <property type="entry name" value="GroEL-intermediate domain like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00750">
        <property type="entry name" value="TCP1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00751">
        <property type="entry name" value="TCP1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00995">
        <property type="entry name" value="TCP1_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10 11" id="KW-0143">Chaperone</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011381"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00016107"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU004187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU004192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="OBZ82057.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="533" mass="57715" checksum="8F63B8111DB383B1" modified="2016-11-30" version="1">MAQVAKPQAAKTNNGNFQDKEKPMEVRMSNITAAKAVGDAIRTSLGPRGMDKMIQTGSGEVVITNDGATILKHMAVLHPSAKMLVDLSAAQDVEAGDGTTSVVVLCSSLLSAAEKMLNKGIHPTTIAESFQRAAAKSVEFLTEMATPVDLSDRESLLRAASTSLNSKIVSQYSSLLAPIAVDAVTRIIDPATASNVNLNDIRVVKKVGGTIDDTELIDGLVLNQTVLRSAGGPTRIEKAKIGLIQFQLSPPKPDMENQIVVNDYRQMDKILKEERQYLLNMCKKIKKSGCNVLLIQKSILRDAVNDLALHFLSKLKIMVVKDIERDEIEFIAKSLDCKPVADIESFTDDKLGYADLIEETENAGARIVKVTGMKHAGKTVSVICRGANSLVLEESHRSLHDALCVVRCLVKKKFLIAGGGAPEIEISQKLMEYAKTLTGMEQYCFQAFAEALEVIPTTLAENAGLNPIAIVTELRNKHALGEKTAGINVKKGTITNILDENVIQPLLVTSSALELSAETVKMIMKIDDLVQSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MZ15</accession>
    <name>A0A1C7MZ15_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">N-acetylated-alpha-linked acidic dipeptidase 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">Naalad2</name>
        <name evidence="3" type="ORF">A0J61_09789</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000937">
        <property type="protein sequence ID" value="OBZ82165.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MZ15"/>
    <dbReference type="STRING" id="101091.A0A1C7MZ15"/>
    <dbReference type="InParanoid" id="A0A1C7MZ15"/>
    <dbReference type="OrthoDB" id="5841748at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004180">
        <property type="term" value="F:carboxypeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.10">
        <property type="entry name" value="Zn peptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046450">
        <property type="entry name" value="PA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039373">
        <property type="entry name" value="Peptidase_M28B"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10404">
        <property type="entry name" value="N-ACETYLATED-ALPHA-LINKED ACIDIC DIPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10404:SF46">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52025">
        <property type="entry name" value="PA domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53187">
        <property type="entry name" value="Zn-dependent exopeptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="59"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="27"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="29"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="214"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ82165.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="214" mass="24071" checksum="C05E0F4B938DD787" modified="2016-11-30" version="1" fragment="single">MAGGISLPSDENNEGVKGNLQKAKDWFNSKWNGGQDENTPLLDRQRGTMSAPRRTTFRTVVTISAIVAIFVLIGITFGLWFDNIEKEEPKPTPPGKINPEKMMLEMPSNESIRDYLKIYTSEAHLAGTENDKKQAEWTLNQFKNFGLDAKIETYYPLLNYPVSHRLALVSGPKHLRFEAKLTEDPVDEDETSKDPNVIPTFHGYSKNGTVTGRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-06-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MZA7</accession>
    <name>A0A1C7MZA7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_10203</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001071">
        <property type="protein sequence ID" value="OBZ81749.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MZA7"/>
    <dbReference type="InParanoid" id="A0A1C7MZA7"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="38"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ81749.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="102" mass="12007" checksum="4488FB684D886090" modified="2016-11-30" version="1">MNYMQNGDNVEQTKTLPEQAFTREQVIAILQEFQQRQGQQEMEENWRGPNLPKGIADDLDNTPFHEVLQTLKSFKRNVEKYNNKERIKPESINPNFTNQLKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MZU4</accession>
    <name>A0A1C7MZU4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_10015</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001002">
        <property type="protein sequence ID" value="OBZ81936.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MZU4"/>
    <dbReference type="STRING" id="101091.A0A1C7MZU4"/>
    <dbReference type="InParanoid" id="A0A1C7MZU4"/>
    <dbReference type="OrthoDB" id="2248071at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="46"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="78"/>
            <end position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ81936.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="358" mass="41225" checksum="2064840DF76DC74D" modified="2016-11-30" version="1">MTSNIFVAQTFNGEKMVNASSRKSTVTSEEQMPIQKSTEQTLVPLAPAPPPPPPPPPSQPVPIAPVIAPAPPPPPPQSISIASSPAQLDKPESIQPPSPSKENNKGYQGRVHDIAVNRPKRAPAFAHPFPFTPTNNNPPAALPQQTIVRLPYPPSTPRPIYWSEADTAILIQLHRKYYPAIQEDALDKENGAWSRLTTEFNMITQEQHTMLDLHHRWVQLMAKYNAERAHLMLQHRQASLQPQPFHVPSYWSHFQYMDLYLHHLPVPEDALYYQTQPTTPQKRPRLHEHDVELTQQLFETHRTSMQEQANQMKLMKQHYESMFKMNDKYMQLCERLFHQSQASEDRYRVLFDKIIEKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N052</accession>
    <name>A0A1C7N052_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_09494</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000863">
        <property type="protein sequence ID" value="OBZ82453.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N052"/>
    <dbReference type="InParanoid" id="A0A1C7N052"/>
    <dbReference type="OrthoDB" id="5598377at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ82453.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="97" mass="10982" checksum="5130355295707E3D" modified="2016-11-30" version="1">MVGFYNSLYNLAHTHLNDTYELLTSLQGRLSPAQTTTLMQSTSWDEIIFVSQRSPRKSSPGLDGLPYEILDILIRVPCFHGLILTSQPVRFGSCYRC</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N0E0</accession>
    <name>A0A1C7N0E0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">DNA-directed RNA polymerase II subunit RPB3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">rpb3</name>
        <name evidence="8" type="ORF">A0J61_11136</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the archaeal Rpo3/eukaryotic RPB3 RNA polymerase subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001706">
        <property type="protein sequence ID" value="OBZ80814.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N0E0"/>
    <dbReference type="FunCoup" id="A0A1C7N0E0">
        <property type="interactions" value="633"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N0E0"/>
    <dbReference type="InParanoid" id="A0A1C7N0E0"/>
    <dbReference type="OrthoDB" id="270173at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000785">
        <property type="term" value="C:chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005665">
        <property type="term" value="C:RNA polymerase II, core complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003899">
        <property type="term" value="F:DNA-directed RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003968">
        <property type="term" value="F:RNA-directed RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006369">
        <property type="term" value="P:termination of RNA polymerase II transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006368">
        <property type="term" value="P:transcription elongation by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006367">
        <property type="term" value="P:transcription initiation at RNA polymerase II promoter"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd07031">
        <property type="entry name" value="RNAP_II_RPB3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.170.120.12:FF:000002">
        <property type="entry name" value="DNA-directed RNA polymerase II subunit RPB3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.120.12">
        <property type="entry name" value="DNA-directed RNA polymerase, insert domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1360.10">
        <property type="entry name" value="RNA polymerase, RBP11-like subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00320">
        <property type="entry name" value="RNApol_arch_Rpo3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001514">
        <property type="entry name" value="DNA-dir_RNA_pol_30-40kDasu_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011262">
        <property type="entry name" value="DNA-dir_RNA_pol_insert"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011263">
        <property type="entry name" value="DNA-dir_RNA_pol_RpoA/D/Rpb3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036603">
        <property type="entry name" value="RBP11-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022842">
        <property type="entry name" value="RNAP_Rpo3/Rpb3/RPAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036643">
        <property type="entry name" value="RNApol_insert_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050518">
        <property type="entry name" value="Rpo3/RPB3_RNA_Pol_subunit"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF001988">
        <property type="entry name" value="PRK00783.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11800">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11800:SF2">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01000">
        <property type="entry name" value="RNA_pol_A_bac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01193">
        <property type="entry name" value="RNA_pol_L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00662">
        <property type="entry name" value="RPOLD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56553">
        <property type="entry name" value="Insert subdomain of RNA polymerase alpha subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55257">
        <property type="entry name" value="RBP11-like subunits of RNA polymerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00446">
        <property type="entry name" value="RNA_POL_D_30KD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 8" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <feature type="domain" description="DNA-directed RNA polymerase RpoA/D/Rpb3-type" evidence="7">
        <location>
            <begin position="23"/>
            <end position="263"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00025804"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00072506"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00662"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OBZ80814.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="282" mass="32077" checksum="C5B5A2CF9BC9CF9A" modified="2016-11-30" version="1">MDIGGTYGLGGPNITIRELTKDRISFILSDTDLSVANSLRRVMIAEVPTVAIDMVEIETNTTVLADEFLAHRLGMVPIDSRDVDKLRYTRKQDCTCSQYCPECSVELTLHVKCTDERTKDVTTRDLSSSNPSFMPVLQDKDDSGVLLVKLRRGHELKLKCIAKKGVAKEHAKWSPVSGVAFEYDPYNKLRHTSYWFEETVDEWPLSKNAQYEQPPDKDAPFDYNAKPDRFYFETETVGSLAPEEVVTMAMKILVDKLAYVQMQIQEEVDTKEQDNANAWSNY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N0M8</accession>
    <name>A0A1C7N0M8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_09330</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000826">
        <property type="protein sequence ID" value="OBZ82622.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N0M8"/>
    <dbReference type="InParanoid" id="A0A1C7N0M8"/>
    <dbReference type="OrthoDB" id="2282604at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="21"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="21"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ82622.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="137" mass="15707" checksum="4BA20DC1696414B7" modified="2016-11-30" version="1">MSLCSSQQQEKQTIDFILDDKRTPATPEDGRFPMIVDTSDPTSNRLSNYQQYIHHYGKPASQESLVDTRPPPTPTELQYIKRIHTLMTLVAKQTKEIQSLRSIIEAYSQNELNYTESHSCCGNDSCNISRKRNKHCS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N169</accession>
    <name>A0A1C7N169_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_10837</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001432">
        <property type="protein sequence ID" value="OBZ81114.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N169"/>
    <dbReference type="InParanoid" id="A0A1C7N169"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="103"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="141"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="151"/>
            <end position="164"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ81114.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="164" mass="18240" checksum="E672510D01C7D6A8" modified="2016-11-30" version="1">MKKLIVSTELIKKALKNAEGIENTEVAYKIFSGLASPKPVTWNTVYKANASIMAITKYDPANFEVNWAVLHLVRRAYSNKYNYYTKLVKEGYKVIEESMSSLAKKAPSKKEAPEQDEINDTSFEGSEPSSSEDEEKTPVSLKRKSTKAFSKKATGGSKAKTTSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N1T6</accession>
    <name>A0A1C7N1T6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">methionyl-tRNA formyltransferase</fullName>
            <ecNumber evidence="2">2.1.2.9</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">MTFMT</name>
        <name evidence="7" type="ORF">A0J61_08930</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the Fmt family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.2.9" evidence="2"/>
    <dbReference type="EMBL" id="LUGH01000738">
        <property type="protein sequence ID" value="OBZ83017.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N1T6"/>
    <dbReference type="STRING" id="101091.A0A1C7N1T6"/>
    <dbReference type="InParanoid" id="A0A1C7N1T6"/>
    <dbReference type="OrthoDB" id="10268103at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004479">
        <property type="term" value="F:methionyl-tRNA formyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd08646">
        <property type="entry name" value="FMT_core_Met-tRNA-FMT_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12230">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005793">
        <property type="entry name" value="Formyl_trans_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002376">
        <property type="entry name" value="Formyl_transf_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036477">
        <property type="entry name" value="Formyl_transf_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041711">
        <property type="entry name" value="Met-tRNA-FMT_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11138">
        <property type="entry name" value="METHIONYL-TRNA FORMYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11138:SF5">
        <property type="entry name" value="METHIONYL-TRNA FORMYLTRANSFERASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02911">
        <property type="entry name" value="Formyl_trans_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00551">
        <property type="entry name" value="Formyl_trans_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53328">
        <property type="entry name" value="Formyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Formyl transferase N-terminal" evidence="5">
        <location>
            <begin position="24"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="domain" description="Formyl transferase C-terminal" evidence="6">
        <location>
            <begin position="153"/>
            <end position="263"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010699"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF02911"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OBZ83017.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="570" mass="63629" checksum="82546C92C72768DD" modified="2016-11-30" version="1">MNQLSVFHTPPQVKTLNDWQLPSETEYDLGVVVSFGYFIPPHIIDRFKYGAINVHPSLLPKYRGAAPIQHAILYGDKETGVTIQELDPHEFDAGRILAQVKTPLDTPPIYSTLKPKLAEVGSRLLVDTLNHLKERKEHAVTQDITQATRAPKVQKTWSEMDFVNTSAWQAEQLNRAIGEQYPLRTIYQTHSKKFKDIVVQLLKLDVAQNPDKDLTGSAPGSFRFHEPSQSLHIVCGDQSVLACSQLKVQNKGAVSAKDFCNGYQSEGQFGVSLGVDDLIVERNMKKRAKMKPFNQLEIDEEQFDEGVITVATSSAPLEEEELILLKSIQKFEPFIREQEKSRGVDQILGLKSKVKSTASSLYEEENGVDLNEPVLGIFFGLQKHIKEHMHHINLDQRSLLKRIAYVDELSGIAAQAMVSTLNQAKLKSAKLPELHTLKNQISQIQDDAAHIFKTLSALEEQLGPADRISSDIKATRWPELNQFRTDASKPSIERYISSSSDLAIVATTSAPFMLDQMLEENGNENVTDVHRTDEGKTSNAVEPNSASVSLALDRLRGLSSQSLATEEDNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N216</accession>
    <name>A0A1C7N216_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_09281</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000815">
        <property type="protein sequence ID" value="OBZ82669.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N216"/>
    <dbReference type="InParanoid" id="A0A1C7N216"/>
    <dbReference type="OrthoDB" id="2289342at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="94"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="106"/>
            <end position="118"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ82669.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="362" mass="41913" checksum="4569D3D5E6C64E8F" modified="2016-11-30" version="1">MHIPCLPNNNMPSDSQRRQSYLNNNSAFDLTWKNYIPSLSDFCYCFKQGNIRLEDDIVVEPAYYNDHTLHRGDALNSSRDWEFESVLSQSDFVTRNPFGHNDSTARRKKSHSKRGSRKNRFERPAVMETDMEDEHFAGYDLYDNEDAEFLADDQIAHLAYYRPDLEVTDQFGEEEYVQYVHGPIVQEMHTQREFYAARTMPEINFDDQESLSSRPLINEATQNFLNHQLKDASDKLNFVKNTIIDTGSQNSHDEDETDRHTLHTLHPHEESNLIATSDIDSVASEALDVYESTASQSQHITRRYSDELHLPSLHDNTPFVSDQHPFSYISEQNQSNSNIQEPSNNELNVQSVLDIGRKWLGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N234</accession>
    <name>A0A1C7N234_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">CUE domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_08746</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000703">
        <property type="protein sequence ID" value="OBZ83205.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N234"/>
    <dbReference type="InParanoid" id="A0A1C7N234"/>
    <dbReference type="OrthoDB" id="9942608at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043130">
        <property type="term" value="F:ubiquitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031624">
        <property type="term" value="F:ubiquitin conjugating enzyme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006511">
        <property type="term" value="P:ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.10">
        <property type="entry name" value="DNA helicase RuvA subunit, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003892">
        <property type="entry name" value="CUE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009060">
        <property type="entry name" value="UBA-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16461">
        <property type="entry name" value="TOLL-INTERACTING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16461:SF5">
        <property type="entry name" value="TOLL-INTERACTING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02845">
        <property type="entry name" value="CUE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00546">
        <property type="entry name" value="CUE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46934">
        <property type="entry name" value="UBA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51140">
        <property type="entry name" value="CUE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CUE" evidence="2">
        <location>
            <begin position="34"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="158"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="213"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="301"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="160"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="178"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="213"/>
            <end position="225"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ83205.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="357" mass="40349" checksum="A88DDE3F86CAEEE7" modified="2016-11-30" version="1">MSEPQTRPTEELMSAPDSEHRVADVDPQTTPTPESTGPLKTLKDAFPDLDLDIIQTILASQDNRLDAAFEVLLGMSDPSYKPEPEQLEGLTQMQQDEAYARQLSREAYGQPTQDNSNRNNEPLFNFQEELPVIKEKVIEAGIAAKNKLVNLYNQFMEGPSESQQQQQQQTSTRQSNSLEDNMNNLRLSDNQNTNVDLYGGEGRMPVRSLYEQPNAQPNAQPNAQPKNTTSTPKEQLLSDEEFARRLAREDSELDITPTLSDTRHHEVVNQEPLNTTQKPAELLSTQHDSDQNEVTLSAVTQDTNSGYTHPKQLEHDDXDDLFNKPGKQKGKEEKPIVPTIFIHSIEEEEEAYKIKEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N2A8</accession>
    <name>A0A1C7N2A8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_08673</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000691">
        <property type="protein sequence ID" value="OBZ83275.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N2A8"/>
    <dbReference type="InParanoid" id="A0A1C7N2A8"/>
    <dbReference type="OrthoDB" id="2152896at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="100"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="152"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="108"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="172"/>
            <end position="182"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ83275.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="221" mass="24616" checksum="1AF2DF48E3AA9570" modified="2016-11-30" version="1">MAVSNHSTTTNNTVDTVKESAGKLPPPSVLFESNYFYNQNKSNANETPVNANSRQVYILPPPSSLPGYHLPPPNTTTPVAQNTAYYYPQQQQSQHEYHPQYFYPSPVAPTTGTKRNNTNNHTPKKRAKKTTTTTTTVANDDISLAAATLASFASSPSSSSNEEDEFEVKKEIPRKKRQYRKSNNKEDHLSSLKQQENQVLEAARILMDISRCVARQVSVAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N2D4</accession>
    <name>A0A1C7N2D4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_08671</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000691">
        <property type="protein sequence ID" value="OBZ83273.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N2D4"/>
    <dbReference type="STRING" id="101091.A0A1C7N2D4"/>
    <dbReference type="InParanoid" id="A0A1C7N2D4"/>
    <dbReference type="OrthoDB" id="96345at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33324">
        <property type="entry name" value="EXPRESSED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33324:SF2">
        <property type="entry name" value="MYB_SANT-LIKE DNA-BINDING DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="174"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="242"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="192"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="202"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="253"/>
            <end position="267"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ83273.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="354" mass="40677" checksum="F63EDDC18149640F" modified="2016-11-30" version="1">MMTPYTSTRTAPTPPTKAKKPYKSWLKDGVNGGPSSMEVLVNWLSKKANYAKWKGDDCERIPKKSLLESIIDEMREVGIYHRLAKDVASKISTLQSNYRLVREWKEVEGKKLLESGVSEAGIHDELLKRFPYWDTLNEVFNSSRTASWPMSISSIMHTEEDELFHVKQEDYSFDEDEDDILPPHKRRRRLSDSTVQPTQRCSVDSTTDSVSTVHSTQSLPNHIHSAPILVKPLPRVLPSLNKPYSLPPPPPMTKNSPPSSNHLPLPHTFLDPQHNRRDQMIAESLLQITREKEAGRMKRSQDMLQFLREKRMERDQLLIEKELTKRVKAKAELVKNLMEAGFDKNAIAEQLNML</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N382</accession>
    <name>A0A1C7N382_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">GTP-binding protein yptV4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">YPTV4</name>
        <name evidence="1" type="ORF">A0J61_08473</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000655">
        <property type="protein sequence ID" value="OBZ83477.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N382"/>
    <dbReference type="STRING" id="101091.A0A1C7N382"/>
    <dbReference type="InParanoid" id="A0A1C7N382"/>
    <dbReference type="OrthoDB" id="9989112at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:001447">
        <property type="entry name" value="Ras-related protein Rab-1B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050209">
        <property type="entry name" value="Rab_GTPases_membrane_traffic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001806">
        <property type="entry name" value="Small_GTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47979">
        <property type="entry name" value="DRAB11-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00071">
        <property type="entry name" value="Ras"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00449">
        <property type="entry name" value="RASTRNSFRMNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00175">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00173">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00174">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51419">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51421">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ83477.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="155" mass="17173" checksum="041FD099E2C815D3" modified="2016-11-30" version="1" fragment="single">AGQESFRSITQSYYRGAAGALLVYDISRRETFEHVSSWLAAHGRFPLTDAPRKDIRTHANPHTTIVLVGNKSDLDHRQRQVTYEEGEAFARENGIPLFIETSAKSAENVENVFAQTAENVYEKIQTGIFSPNETSGIRLGHTQSALAEETQSGCC</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N393</accession>
    <name>A0A1C7N393_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">DNA repair protein XRCC4</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_08345</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000633">
        <property type="protein sequence ID" value="OBZ83605.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N393"/>
    <dbReference type="STRING" id="101091.A0A1C7N393"/>
    <dbReference type="InParanoid" id="A0A1C7N393"/>
    <dbReference type="OrthoDB" id="8064436at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="246"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="159"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="246"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="263"/>
            <end position="272"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ83605.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="279" mass="32416" checksum="823FEFB50F94323F" modified="2016-11-30" version="1">MVHLYSFYDSVTEKETFHIQSEWLGNKIELNKENESDLDYCFVTITNLVDYWNCKVTRNLLLERFQVSNALTEDHRDAVLTAALQGEQSVCGDRLEWRVSRHPEEEEKLQMKLRTYDGDVALTAGTFLLEKVAPTEKNELHQNWFKHCTIASRVCIEANRALQQRILDIEKTCNEYKETIEAMTTKMNQSKFIVLDKFTNLLNSKKRKTKAYKDEYKKSSKRRTTQASLEIKQEIQSKPLVESLEISSQTKVKSTSLPLSHEDDSDFSDDGIDCPQTVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N3H3</accession>
    <name>A0A1C7N3H3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein C4C5.03</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">SPAC4C5.03</name>
        <name evidence="6" type="ORF">A0J61_08320</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000629">
        <property type="protein sequence ID" value="OBZ83631.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N3H3"/>
    <dbReference type="InParanoid" id="A0A1C7N3H3"/>
    <dbReference type="OrthoDB" id="19344at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.290">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051415">
        <property type="entry name" value="LAAT-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006603">
        <property type="entry name" value="PQ-loop_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16201:SF11">
        <property type="entry name" value="PQ-LOOP REPEAT-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16201">
        <property type="entry name" value="SEVEN TRANSMEMBRANE PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04193">
        <property type="entry name" value="PQ-loop"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00679">
        <property type="entry name" value="CTNS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="27"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="58"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="101"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="155"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="191"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="221"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="251"/>
            <end position="274"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OBZ83631.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="296" mass="33351" checksum="8B899E315C96CB3A" modified="2016-11-30" version="1">METVVKILNYSQEKAKECVPLNDKTTLFISLFLCIGLVISYLPQHYRIIANKTSEGFSAWFLLLGVVSSTSSFFNIILLQWDAIVCCKSLSTGACFEGLMGVIQIGLQWAMFSLVFVLFLLYFPESKKRQLHAPRSLHLDLPNNIQSPLSNEWKVSLVVAAVCIGHLALSFFISVLLLVFVGGPDHWQTNYWAAFLGILSMILASLQYIPQIYKTWQSKKVGAISIPMMMLQTPGTALFVYSLIVRPGTNWTAWLTYMVTGVLQGTLLVMCIVWHYRNKKLGLPDIEPTETTRLLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-06-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N3Y5</accession>
    <name>A0A1C7N3Y5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_08220</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000613">
        <property type="protein sequence ID" value="OBZ83728.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N3Y5"/>
    <dbReference type="InParanoid" id="A0A1C7N3Y5"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ83728.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="64" mass="7432" checksum="FBB10A2C1CFB0E38" modified="2016-11-30" version="1">MFVPFSSHNHTVYTPKQISTKDVLPISLTFEFICFISAEDVASATTNYAPYHKNYLKRFMPEEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N4J8</accession>
    <name>A0A1C7N4J8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_07996</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000578">
        <property type="protein sequence ID" value="OBZ83958.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N4J8"/>
    <dbReference type="STRING" id="101091.A0A1C7N4J8"/>
    <dbReference type="InParanoid" id="A0A1C7N4J8"/>
    <dbReference type="OrthoDB" id="3039677at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ83958.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="150" mass="16328" checksum="EC515D295D3F5E98" modified="2016-11-30" version="1">MILIGVIPGPSEPPTTAINHYLEPLVKEMLELVQGVDLQVTLMDGTVVYNKVRAAITLISCDLPATKKLIGSLSFNSHHACHMCDLVFPSLPGGVSKHNYCDWNCDSWPRKDPAVPRQASEQWIRATTKAARSNITAATGSRNGCSRQVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N5L4</accession>
    <name>A0A1C7N5L4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_09307</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000820">
        <property type="protein sequence ID" value="OBZ82644.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N5L4"/>
    <dbReference type="InParanoid" id="A0A1C7N5L4"/>
    <dbReference type="OrthoDB" id="2272123at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ82644.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="125" mass="14246" checksum="504B70AAAC6915BF" modified="2016-11-30" version="1">MDLNICLYCERYLSEENMNFCSSVCQAREASKPISSRLYMMGSRLPTTSINYESAQHRRSSFSSDHCPLPSSSSSSINSTYSLTSLDSNTKQHYHISYHILLSQPSRHSDPQPNQQNVYTNCFFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N5M9</accession>
    <name>A0A1C7N5M9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">RNB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">A0J61_08000</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the RNR ribonuclease family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000579">
        <property type="protein sequence ID" value="OBZ83949.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N5M9"/>
    <dbReference type="STRING" id="101091.A0A1C7N5M9"/>
    <dbReference type="InParanoid" id="A0A1C7N5M9"/>
    <dbReference type="OrthoDB" id="2285229at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000932">
        <property type="term" value="C:P-body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000175">
        <property type="term" value="F:3'-5'-RNA exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006402">
        <property type="term" value="P:mRNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.700:FF:000002">
        <property type="entry name" value="Cell wall biogenesis protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.690">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.700">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041505">
        <property type="entry name" value="Dis3_CSD2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001900">
        <property type="entry name" value="RNase_II/R"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050180">
        <property type="entry name" value="RNR_Ribonuclease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033771">
        <property type="entry name" value="Rrp44_CSD1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23355:SF9">
        <property type="entry name" value="DIS3-LIKE EXONUCLEASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23355">
        <property type="entry name" value="RIBONUCLEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17849">
        <property type="entry name" value="OB_Dis3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00773">
        <property type="entry name" value="RNB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17216">
        <property type="entry name" value="Rrp44_CSD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00955">
        <property type="entry name" value="RNB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0540">Nuclease</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RNB" evidence="7">
        <location>
            <begin position="450"/>
            <end position="759"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="95"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="28"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="53"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="65"/>
            <end position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005785"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00955"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OBZ83949.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="873" mass="99246" checksum="3CCBA7FDA1CA4B59" modified="2016-11-30" version="1">MQLQHDSQHPLALNKHDTKSNAVEVKMTRRRSRGRRRSSSEFTFTEDDPQPNKPHRRRSSHGTRPKPEENKKKDSPAFQSIVDIISEIKRLPTGSIYQSSDSKRIRRHSEPPQLTLEGAQQGLTTIQEQTLSKDMASLSLEPQEDTIIKRNRSQSVPSTTLSFHSENSNRRLLYTPHMKTSEATAAVRSRQLYSGILRVSSQDSSEADVDCEQLDSSIYIFGSRNRNRALDGDQVVVELVDVDEMLNERQAKRLARQTRRLSAISLQNGSFTSNCGLSSIPEDNVASLERLKEATHRPKYCGKVVCILERPRNMLFSGTLSLSRPYAPTLDNGSRDKKETHSPKIIWFIPADKRLPLVAVPIKHAPPDFIKYHEEYKNRIFIGSIQRWPATSLHPFGIVEQKIGWMGELGVHSRALMADHHIKDSDFTDSVKKAAVAVPAELTDEERKLRRDLTKEDLNIFTLGDQDHAFSITSTEKGMYEVGIHIADVSRYVHTNTPLDREARERSCAIELADAKRVPILPFDFLASHSSLQVGKERLAYSVMCRFTEAGVLLHAWIGHTVIKVKEDVGKTLTEEAKTLLSLCRTLQKIRLETLEGMHLTKPVLLFELADSGYPKQVHRYDPTDEEVLLQELLIIANMEVGQKISCRFPDQALLYRQDSPKLSKLSALIDHFECTPKDIHELIEWIQTKETNMARQQTMMHLVQAAMPPPKYFSAGSLDISKYHHFSFGTPICTVFTEPSQQYASIYVQRQLNAALKGEVQASDQVDPIDKIARHCNSSYLAKVAAEQDSKKLFVAAYIYRECSNTDSGKLSTEAFVISVEREMMTLYLPEFDLSLQVSNDFGYEHPLFLSRLFVHLHVDMRAIRPNFIVEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-06-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N5W0</accession>
    <name>A0A1C7N5W0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_07933</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000568">
        <property type="protein sequence ID" value="OBZ84016.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N5W0"/>
    <dbReference type="InParanoid" id="A0A1C7N5W0"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ84016.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="145" mass="16466" checksum="650F0FD5E7EB3AB3" modified="2016-11-30" version="1">MAKSKSAIQLLRQGSLKKHRSSANLKSSTIPCFEPKHLVFSSLKAQSHLTCENCSLWQVEAKLVARIQLKQDNKYTSRFDEHEEKGEEGLKKNLICLQTEDKTIATVTNIVDTTMKETSEGKLEGSIINPFIQVLLKRNMFFDSH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N602</accession>
    <name>A0A1C7N602_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">alpha-1,2-Mannosidase</fullName>
            <ecNumber evidence="7">3.2.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">Edem1</name>
        <name evidence="9" type="ORF">A0J61_07895</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the glycosyl hydrolase 47 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.-" evidence="7"/>
    <dbReference type="EMBL" id="LUGH01000562">
        <property type="protein sequence ID" value="OBZ84059.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N602"/>
    <dbReference type="FunCoup" id="A0A1C7N602">
        <property type="interactions" value="409"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N602"/>
    <dbReference type="InParanoid" id="A0A1C7N602"/>
    <dbReference type="OrthoDB" id="8118055at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044322">
        <property type="term" value="C:endoplasmic reticulum quality control compartment"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004571">
        <property type="term" value="F:mannosyl-oligosaccharide 1,2-alpha-mannosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1904380">
        <property type="term" value="P:endoplasmic reticulum mannose trimming"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097466">
        <property type="term" value="P:ubiquitin-dependent glycoprotein ERAD pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012341">
        <property type="entry name" value="6hp_glycosidase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044674">
        <property type="entry name" value="EDEM1/2/3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001382">
        <property type="entry name" value="Glyco_hydro_47"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046450">
        <property type="entry name" value="PA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003137">
        <property type="entry name" value="PA_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036026">
        <property type="entry name" value="Seven-hairpin_glycosidases"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45679:SF5">
        <property type="entry name" value="ER DEGRADATION-ENHANCING ALPHA-MANNOSIDASE-LIKE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45679">
        <property type="entry name" value="ER DEGRADATION-ENHANCING ALPHA-MANNOSIDASE-LIKE PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01532">
        <property type="entry name" value="Glyco_hydro_47"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02225">
        <property type="entry name" value="PA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00747">
        <property type="entry name" value="GLYHDRLASE47"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52025">
        <property type="entry name" value="PA domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48225">
        <property type="entry name" value="Seven-hairpin glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0106">Calcium</keyword>
    <keyword evidence="3" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="4" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="7" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PA" evidence="8">
        <location>
            <begin position="683"/>
            <end position="764"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="5">
        <location>
            <position position="89"/>
        </location>
    </feature>
    <feature type="active site" evidence="5">
        <location>
            <position position="230"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="5">
        <location>
            <position position="325"/>
        </location>
    </feature>
    <feature type="active site" evidence="5">
        <location>
            <position position="344"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="430"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007658"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR601382-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR601382-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU361193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OBZ84059.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="805" mass="91458" checksum="B6ACBA544A3880FC" modified="2016-11-30" version="1">MFEHGWSHYMQYAYPEDELNPFQCSGRGSDKADPHNINVNDVLGDYSLTLVDTLDTLAIIGTQKQFEEAVRLVIETVSFSQDSKVQVFELNIRALGGLLSAHLLATDPSFNYTIPGYQGELLEMAINLADRLIPAFESTKTGIPYPRVNLIHGVPPTETTETCTAGAGSLLLEFGVLSRLTGNSVYEKVAKRSLDAIWHRRSEIGLLGNVIDIQTGRWIHTASSTGAGIDSIFEYMLKSYVLFGEQEYKDMFDEAYRALMLHVRDASGYLYRNVHMSSGTLMSYWIDSLSAFFPGLQVLYGDLDAAIKGHLIYFNIWRRYQALPERFDFFQKTVDLPYYPLRPEFIESTYHLYMATKDPFYLQVGEMVLEDLNNRTRVPCGFATLGDVRSGRQEDRMESFMLSETLKYLYLLFDSDHVINKMDSNYVFTTEGHILPLSAQYLKKKKKKDEIPSQAKAVVSFQRSAAGTCERYNPMRQHYLSTPGHLDMSSLLHQPISDYAADIVGITNPVQPLTSTGYCEVPQRHGPFSLSFSYQRYQQKQANYPVLTQHTLVDLLGGYLAKSLSGFKLDIIGDSQGYFVKRVSPHNISSHFSKKSLNSTQKLIVPMHSFLNYASQDLFEIWIRQPRLTTHLRNYFQSDDEVSIKATNHHICVEFLGVKSALGPLAPISLIGQTHVFHDKDVYGCDPYDTHQVHQIRDKILLISRGHCSFYQKILYAQQAGARAVILMNNQPDQAPFRATGSDNNNENLMIPSLMLSYEDSLQLVKHDWQQFSVQQLPSVDSDPNASFLVRFHGQWLHNLEILNV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N606</accession>
    <name>A0A1C7N606_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_07514</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000510">
        <property type="protein sequence ID" value="OBZ84441.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N606"/>
    <dbReference type="InParanoid" id="A0A1C7N606"/>
    <dbReference type="OrthoDB" id="2215566at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ84441.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="210" mass="23480" checksum="78EC0E94D6174910" modified="2016-11-30" version="1">MPKFITLALGYLTVPLEIKSSIRTLTTEPGSRESKAAYWGYVSTISINCFVQSPPTIYPTHEKHVVQLKDDANLFEQETLVTLSSSMNPEGGPKSHGLITITDDLLGILSATDHHATFVLQIVQFDSKGTDSKSYHSQTKTPSLELSAKPAAIMELCQLWPNSKNQLAKIGAHVYQLACLYGYWDNWRIFEGICQTHQIDVDQLLNIQRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N6F8</accession>
    <name>A0A1C7N6F8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Putative endonuclease LCL3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">LCL3</name>
        <name evidence="7" type="ORF">A0J61_07312</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LCL3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000486">
        <property type="protein sequence ID" value="OBZ84637.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N6F8"/>
    <dbReference type="FunCoup" id="A0A1C7N6F8">
        <property type="interactions" value="4"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N6F8"/>
    <dbReference type="InParanoid" id="A0A1C7N6F8"/>
    <dbReference type="OrthoDB" id="430293at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035437">
        <property type="entry name" value="SNase_OB-fold_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016071">
        <property type="entry name" value="Staphylococal_nuclease_OB-fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12302">
        <property type="entry name" value="EBNA2 BINDING PROTEIN P100"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12302:SF3">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE 31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00565">
        <property type="entry name" value="SNase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00318">
        <property type="entry name" value="SNc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50199">
        <property type="entry name" value="Staphylococcal nuclease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50830">
        <property type="entry name" value="TNASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0106">Calcium</keyword>
    <keyword evidence="3 7" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0540">Nuclease</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TNase-like" evidence="6">
        <location>
            <begin position="90"/>
            <end position="246"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005435"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50830"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OBZ84637.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="266" mass="30582" checksum="41CCFEFEDA82BC2E" modified="2016-11-30" version="1">MANNSDFWTQVQQLFRNEKNDFWTDLKQRIEREKPSWDQRADELVQSLWRPITLGLLIGLPALYFANKVLIGRRFKTAEHIPPEAFERSQTIRGRVVAVGDSDNFRLYHTPGFGWGWARQVPKTKKELQKQTISVRIAGVDAPEGAHFGMPAQPYSKEAKAFLTDLVLNQKVRLQLLSRDQYGRVVGMAYVRRPPFYFEKNVSAEMLKAGLASIYTAKGAQYGGVFEKLKRYEARAKFFKRGIWSLQFYISPGDHKAKFLSGKSKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N702</accession>
    <name>A0A1C7N702_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_07105</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000463">
        <property type="protein sequence ID" value="OBZ84841.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N702"/>
    <dbReference type="InParanoid" id="A0A1C7N702"/>
    <dbReference type="OrthoDB" id="2290530at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="146"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="146"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="156"/>
            <end position="178"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ84841.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="610" mass="71023" checksum="32F95F8B5B249CF0" modified="2016-11-30" version="1">MATDEEIIKGLRQELCVPDFWIEKEWQQWSVQNFDYEATRQNPGITRSVAHNDLSKDLNTLIKALNKSGRKTQRLKQMKLSLKTAHANSVNSHFWRVRAVKSAKLSDARFIARISRAVAEVLILFQTENLATATLTKIAKDVEPQDFNKRKHEEMTDNEECDQEENEEADGYDEENDNNGDYVTKKKHEKEDDKKEEFIDSIQKNIVISNNDARHELFKWAFKLQHKNEEYTPSNDAIDEILLKRDSNLDYLNHLSISILQNWVDNDEVLSHILRISLSGIIDLAHSWTAQYCKNVFPDARWSEFEELKYPLYNLTEESSDIYNNVMKILKNEDAQLGLERQPEHEALVYLSEKRHEYSVSMNNIYYLNGNESELECMEDCYSILKIAFRGSKYKFKLGEQACIESKTVREENEKAYANNENFDSAQNIMGRRIDLLLSSYETNVSSCEWKAENVSPSVARSQESKNLRVNASILEALLRLPHENNDSNRNSFVLMYSDWIGRDGCINTIVKEGNVFIVKKLGDVFIPKSVHEIDEEFKLTIKLLYTWKKNMDALVGLVLQGINKKRRDLKKAKMSVVNNNNEEPRFIFFTPKNNRTRPSELRERNPSED</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N734</accession>
    <name>A0A1C7N734_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_07093</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000461">
        <property type="protein sequence ID" value="OBZ84867.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N734"/>
    <dbReference type="InParanoid" id="A0A1C7N734"/>
    <dbReference type="OrthoDB" id="10675984at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="126"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="190"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="244"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="353"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="223"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="244"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="265"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="369"/>
            <end position="381"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ84867.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="416" mass="45742" checksum="87B016BFC578223B" modified="2016-11-30" version="1">MKLRKVKLQLSLLIPRQIRDSEVEKENLMLFQLHNYNKTVSIVLLTQELLDTHLPNFDLSEANPCFAARVNIQGAYDRDSYNFSRHPKLPLYAIRVDRLEVLAPSVPIPVQCLAIQQKLEERLALRSNHSESPATVDEIGYESSDSDSSEYYATIDNPNEPSSSAGSSSGIRPHPSTTSAARVLMTSGLVASSPPSLPEARLQDSRDSELSSLSSGDEAVTHVKTSSQHNSNVQTLADSLTIPQQANNESGSSSDRQYYPTNSPKGKRRSTKKGHSPNESVKKAASGATARSKVKPTQTSTTKTRKLRNQAPENKIPLYQEAESSVSTELVITTAAAITTPTTNDDDDVTVITAVAPTDPEDNPSTSRGRGEKIERKRSSSDTESIDNQQEEPRSIVGSNIRRSSRLVNKRIRYTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N7N6</accession>
    <name>A0A1C7N7N6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_07319</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000487">
        <property type="protein sequence ID" value="OBZ84626.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N7N6"/>
    <dbReference type="InParanoid" id="A0A1C7N7N6"/>
    <dbReference type="OrthoDB" id="2264205at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ84626.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="111" mass="12051" checksum="717BC0A029D45B67" modified="2016-11-30" version="1">MVLSITSSFTLEVDDKNDLINAGLIFAKKRIRILPCPSIVADYEIASVSLTHIPSIRPDEIGTGLPKSLAPFGKIFNVDIFMRSGYAVLGKPKKANSLEIAHTVSCCESED</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N8I9</accession>
    <name>A0A1C7N8I9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_06519</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000396">
        <property type="protein sequence ID" value="OBZ85440.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N8I9"/>
    <dbReference type="InParanoid" id="A0A1C7N8I9"/>
    <dbReference type="OrthoDB" id="2294293at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ85440.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="276" mass="31539" checksum="5484BFF24BB65B40" modified="2016-11-30" version="1">MSTSNNTISNSITLKDFTIACSNTEPFHYKRVNISAALLKLKTEAYQELTGSDSFSFTQDMKKHIVPFLSLYNIIKVEANLASRYKKCPGLEVLCEYRKYLRMKKWGPPKRFPQSLKNEIEDLISDLSDDDFDNILEFQEKISDMKKKTNCKAAKRLLQFTCCLVDNLVESPKKIGEMELQTSIVHTLMLQLFKLNKGYNPYSSNLVFDKHDACLKGVRPDYLVVVNGDYKNVVGEVKSQGSSKSDLEWDLLRLGVFGRQMLETEGLEAVVCFQPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N8J6</accession>
    <name>A0A1C7N8J6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_08276</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000622">
        <property type="protein sequence ID" value="OBZ83674.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N8J6"/>
    <dbReference type="InParanoid" id="A0A1C7N8J6"/>
    <dbReference type="OrthoDB" id="2284518at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="110"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="175"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="253"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="118"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="179"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="193"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="272"/>
            <end position="287"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ83674.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="315" mass="35844" checksum="47ECD18BBAAEE24E" modified="2016-11-30" version="1">MLKQSYRSNYQCYTTVPTRPNHGKHSSRLYDRARQDLFDTTHDHHTTTVPSITTICLLQIQANIIQVLAYLPHHDKAVLKQCLRWILLITLLLLDNLARILNVDQEMKDLKKKKQNRHHPETNEEHRLDDGDVYYHGQCTTQSLTSQQPLSERTSPMLVKRTQQQLVTPIAFFPKSTRKAYTQPSSPTTPTRESAEERKAEGGSRSSRANRVPSHGRSLSNTMIDKDMSPQKLRRVTGQREITVQNAILPIMPRPSVSSTTSRHDRKVMVNSSGLSESSESSATLSAPDQRPKMQKTVSLSTAQQYHKQVEVNIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N8Q3</accession>
    <name>A0A1C7N8Q3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Lipocalin-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_06433</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000388">
        <property type="protein sequence ID" value="OBZ85515.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N8Q3"/>
    <dbReference type="InParanoid" id="A0A1C7N8Q3"/>
    <dbReference type="OrthoDB" id="2264177at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008889550" description="Lipocalin-like domain-containing protein" evidence="2">
        <location>
            <begin position="21"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="274"/>
            <end position="293"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ85515.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="293" mass="31164" checksum="2CEF7198B48892B1" modified="2016-11-30" version="1">MKLFQILTSTMGLLLSTTYAQQDSTIDQSSAFNLSAINGTWHVAGLTDTLVEGFAEISQYLNFSIKCPQIYITGNTTNVSYVQPSFNLEYYNESLGRNLTANISMSGLMTLENVTSPTEANFSVLLAFPTMDNGTSYSSTNNLARILAAGSSYSSSTTLNITAGNVTDPLPNGANISATFGFNLSSSNGSVYDIVLLTASNFSVVSNSSDSSNGNFDDQDNNGYGGNMTEQVYQLLLTNTSTVLNQTIFNQTIDTFGTFASNVTRLNNTCSKSFSSRGGGSQSASVFRAATTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N8R8</accession>
    <name>A0A1C7N8R8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_06956</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000445">
        <property type="protein sequence ID" value="OBZ84996.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N8R8"/>
    <dbReference type="STRING" id="101091.A0A1C7N8R8"/>
    <dbReference type="InParanoid" id="A0A1C7N8R8"/>
    <dbReference type="OrthoDB" id="2020070at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="entry name" value="Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33604">
        <property type="entry name" value="OSJNBA0004B13.7 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33604:SF3">
        <property type="entry name" value="OSJNBA0004B13.7 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="959"/>
            <end position="979"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="960"/>
            <end position="979"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ84996.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="979" mass="112404" checksum="6F476909620926DE" modified="2016-11-30" version="1">MSWLNSPKRLFRLIVLFVFSSAFLLIFLPSFYSSSRTETASDAFSDEDVALDLDRTTSVFSFNTAWDEQTNPWVLKNSIFNTTNNSFLEKLTSYTIEGHNYDTLFNKQPAATQHTQVTIVVPIYTKEAFSKLNIIASWSAVEVAFQVLIACPSQFKPQIEDKLDKNKFGIMAMDRAAITASATGSTFASGTAGAAIWLQMLTEKDITTDYLYVVDENVPISPYTLHELAYLFRAKQRNDYQDALIGTRGYAISPKLVSDNFCLPIDNQLPLNVSQPVDMVLGAWLLHKSWLPHVMSDMSLESLQLPLGYYLSINLKQQLNKPTIFLPSADRHTNLNKLYCEKVKEEWTKNTFWKDSVAKNKYPTALQYRFMSEHSAMIVADGAKQLVSLYPLLCRFKKYPVHLAILGDDLKREIVEHALTETNCQHHVQLHDFSSMKDLKDVSSMASFVSAVQPRILIQIKPAEQSSMLKYNMIQAMGESHQMAAIGLPEKEIPHALWISDLSLEALSYWNKVQIKLVVITDRRPHSLSRLLQSASKSIYLGDRADLVVNMEQSSDRVTRLLVNSLMWRQGTKTIRHRIRKGGLMPAIVESWYPTNNDEYAVLLEDDIEVSPLFYVWSKYAILKYRYSGNSEAHRLMYGISLYAPRNLELLPAGRVTFDPNSVLLPAGYPEHVPYASQVPCSWGGVYFPEHWREFHAYLVTRLKDLELPKDHQVRLISVPGSRSDKWKKSWKKYFIELVYLRGYVMLYPNFQSFEAFSTNHVEFGTHVKSEKRQSVIGTFMVPLMQRDTILSQLPNQSLPLFENLPVLDLWGQLQTYDSLEEQGSKYHQHVSTCERTYGTFDPQEFFCRVDGPPDPLQEFPSAPKKPKPPVLVKDAVQPIRYNRVFEYTREEEEQGRNELLEFGPKPIDVAQLPTVEERFNNRDDEVLDLESDLDTLNRLYLKLNPENLGFLEEERLAMEEEEEDEDIDEGDEIVEDGM</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N8W4</accession>
    <name>A0A1C7N8W4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Heat shock protein 12B</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">Hspa12b_2</name>
        <name evidence="1" type="ORF">A0J61_06386</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000383">
        <property type="protein sequence ID" value="OBZ85563.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N8W4"/>
    <dbReference type="STRING" id="101091.A0A1C7N8W4"/>
    <dbReference type="InParanoid" id="A0A1C7N8W4"/>
    <dbReference type="OrthoDB" id="2963168at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd10170">
        <property type="entry name" value="ASKHA_NBD_HSP70"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.640.10">
        <property type="entry name" value="Actin, Chain A, domain 4"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14187">
        <property type="entry name" value="ALPHA KINASE/ELONGATION FACTOR 2 KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14187:SF5">
        <property type="entry name" value="HEAT SHOCK 70 KDA PROTEIN 12A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0346">Stress response</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ85563.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="923" mass="104905" checksum="31493CAF6D3093F1" modified="2016-11-30" version="1">MTIPFSDKDYPIVIGIDFGTTFSGASYAYLNDNDINDISKWPGQPDYSYPKELIQWGRSAKSGKSKLPNVTVLQQFKLYLDDKLEGIIRQPPLELTSTDIIADYLQKFFNYVKIDMTKKGFHQGFENQVRFCLTVPAMWTDKSKQVMRDAAIQSNLIQATDHRDRLMLISEPEAAALYCEKTCDKFTMTHGDEFMICDAGGGTVDLIVFRVEMDAAGNRTFRESTKGIGKSCGSTFIDRNFRKLLRKKLKKVIRRSPNGTIEIPEAPLEHMMDIFVDNLKPLFDGTDDLYSDISMGFDLITKTEPSIGLDEGNMTFTKEELKKHVFDPVVSEVVQLCRDLQKDTTNLKAIFMVGGFGSSAYLYSQMEKEFVPQNIRIVQPDRPDYPIVIGIDFGTTFSGASYAYLNDNDINDISKWPGQPDYSYPKELIQWGRSAKSGKSKLPNVTVLQQFKLYLDDKLEGIIRQPPLELTSTDIIADYLQKFFNYVKIDMTKKGFHQGFENQVRFCLTVPAMWTDKSKQVMRDAAIQSNLIQATDHRDRLMLISEPEAAALYCEKTCDKFTMTHGDEFMICDAGGGTVDLIVFRVEMDAAGNRTFRESTKGIGKSCGSTFIDRNFRKLLRKKLKKVIRRSPNGTIEIPEAPLEHMMDIFVDNLKPLFDGTDDLYSDISMGFDLITKTEPSIGLDEGNMTFTKEELKKHVFDPVVSEVVQLCRDLQKDTTNLKAIFMVGGFGSSAYLYSQMEKEFVPQNIRIVQPDRPEMAVARGAVIFGMNPTKVTTRVPRFWYGIEITNIFDPAIDPPEYKVTRPDGSVRCDNRFSTYVERGKPLDIDSCVSRNYITYYPSHTACTFYASDSEIEPRYTVSTPTTNVRRVFDFEIPMPMLPHVKHGDPVPLTIKMYFGEVELRVEAVIDNQTYAVVCNFNV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N945</accession>
    <name>A0A1C7N945_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_06298</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000373">
        <property type="protein sequence ID" value="OBZ85655.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N945"/>
    <dbReference type="InParanoid" id="A0A1C7N945"/>
    <dbReference type="OrthoDB" id="2282727at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="46"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="72"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="94"/>
            <end position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ85655.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="162" mass="18484" checksum="8CA6D080BFB312C6" modified="2016-11-30" version="1">MSNSTQTRYTAIKISVLPTTSISSKDNQMPTTISQKGNDRVWLPPLLDALTGLILITMVTSLFYCRHRRRRHTTQQPDNWSHPITQPPPAYSSMREKSPAYSSMREKSSSEPFRLQYSPQLAFSPSFTDLSEFKETSSPAVVCKIEQYDPKVNLPLDHLFCK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N9D5</accession>
    <name>A0A1C7N9D5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Decapping nuclease</fullName>
            <ecNumber evidence="6">3.6.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">rai1</name>
        <name evidence="9" type="ORF">A0J61_06706</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Decapping enzyme for NAD-capped RNAs: specifically hydrolyzes the nicotinamide adenine dinucleotide (NAD) cap from a subset of RNAs by removing the entire NAD moiety from the 5'-end of an NAD-capped RNA.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>a 5'-end (N(7)-methyl 5'-triphosphoguanosine)-ribonucleoside-ribonucleotide in mRNA + H2O = a (N(7)-methyl 5'-triphosphoguanosine)-nucleoside + a 5'-end phospho-ribonucleoside in mRNA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:66928"/>
            <dbReference type="Rhea" id="RHEA-COMP:15692"/>
            <dbReference type="Rhea" id="RHEA-COMP:17313"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:138282"/>
            <dbReference type="ChEBI" id="CHEBI:172876"/>
            <dbReference type="ChEBI" id="CHEBI:172877"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="3">
            <dbReference type="Rhea" id="RHEA:66929"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>a 5'-end NAD(+)-phospho-ribonucleoside in mRNA + H2O = a 5'-end phospho-ribonucleoside in mRNA + NAD(+) + H(+)</text>
            <dbReference type="Rhea" id="RHEA:60880"/>
            <dbReference type="Rhea" id="RHEA-COMP:15692"/>
            <dbReference type="Rhea" id="RHEA-COMP:15698"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:138282"/>
            <dbReference type="ChEBI" id="CHEBI:144029"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="5">
            <dbReference type="Rhea" id="RHEA:60881"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>a 5'-end triphospho-ribonucleoside in mRNA + H2O = a 5'-end phospho-ribonucleoside in mRNA + diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:78683"/>
            <dbReference type="Rhea" id="RHEA-COMP:15692"/>
            <dbReference type="Rhea" id="RHEA-COMP:17164"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:138282"/>
            <dbReference type="ChEBI" id="CHEBI:167618"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="4">
            <dbReference type="Rhea" id="RHEA:78684"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 6">
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the DXO/Dom3Z family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.1.-" evidence="6"/>
    <dbReference type="EMBL" id="LUGH01000418">
        <property type="protein sequence ID" value="OBZ85249.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N9D5"/>
    <dbReference type="FunCoup" id="A0A1C7N9D5">
        <property type="interactions" value="275"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N9D5"/>
    <dbReference type="InParanoid" id="A0A1C7N9D5"/>
    <dbReference type="OrthoDB" id="5853397at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034353">
        <property type="term" value="F:mRNA 5'-diphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004518">
        <property type="term" value="F:nuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0110155">
        <property type="term" value="P:NAD-cap decapping"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000956">
        <property type="term" value="P:nuclear-transcribed mRNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013961">
        <property type="entry name" value="RAI1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039039">
        <property type="entry name" value="RAI1-like_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12395:SF9">
        <property type="entry name" value="DECAPPING AND EXORIBONUCLEASE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12395">
        <property type="entry name" value="DOM-3 RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08652">
        <property type="entry name" value="RAI1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0540">Nuclease</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RAI1-like" evidence="8">
        <location>
            <begin position="44"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="397"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006562"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00044676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00044692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00048124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU367113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF08652"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OBZ85249.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="397" mass="46687" checksum="040D9266A5907B5A" modified="2016-11-30" version="1" fragment="single">MTTRSPESYSPSRDAKRRKRTENEANCFKLENNETYEGTCPVFQQPRELTSYSIDHNRRVWFDNREMKYYYPPTTGKKDLNEGYERTIQRDESISEHIDTLLDALTHFNSEAKEAATADIVTWRGIMTKILCTPYARREPWELRATRYKDTIYLEEQTTEQKKQQESQATEKQKRMSYWGYRFETLCTLSKPPHLVKKDDQELQDRLVQNVNTNIQYCILVKTKLGSSSIIMGAEVDCCRDVKPNDSLKQPSNYIELKTSRIIETDRNQYSFERYKLLKFWAQSFLVGVPRIICGFRDDEGYVLEIKQFKTMEIPRLVRERKNTWNPSVCLNFANALLEWIKSSITKSDAAVTYSIQFKYPFEEIKIECTGHAYVFLTQRYLNGTVQQEIGGPRVPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N9T1</accession>
    <name>A0A1C7N9T1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="14">DNA-binding protein creA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">creA_0</name>
        <name evidence="14" type="ORF">A0J61_06249</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="11">Belongs to the creA/MIG C2H2-type zinc-finger protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000368">
        <property type="protein sequence ID" value="OBZ85708.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N9T1"/>
    <dbReference type="STRING" id="101091.A0A1C7N9T1"/>
    <dbReference type="InParanoid" id="A0A1C7N9T1"/>
    <dbReference type="OrthoDB" id="654211at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000433">
        <property type="term" value="P:carbon catabolite repression of transcription from RNA polymerase II promoter by glucose"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000089">
        <property type="entry name" value="DNA-binding protein creA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000152">
        <property type="entry name" value="DNA-binding protein creA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051007">
        <property type="entry name" value="creA/MIG_C2H2-ZnF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47428">
        <property type="entry name" value="REGULATORY PROTEIN MIG1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47428:SF1">
        <property type="entry name" value="REGULATORY PROTEIN MIG1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 14" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0678">Repressor</keyword>
    <keyword evidence="9" id="KW-0804">Transcription</keyword>
    <keyword evidence="7" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <keyword evidence="5 12" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="13">
        <location>
            <begin position="27"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="13">
        <location>
            <begin position="55"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="14">
        <location>
            <position position="91"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00038023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="OBZ85708.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="91" mass="10705" checksum="40EC5ABEE56D417F" modified="2016-11-30" version="1" fragment="single">MTTSFYSAPVTKRAISPVDKANIPRPYKCPICPKSFYRLEHQTRHIRTHTGEKPHQCTFPGCAKKFSRSDELTRHVRIHTSPNKRRMRKQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NA23</accession>
    <name>A0A1C7NA23_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">60S ribosomal protein L5-B</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">rpl5b</name>
        <name evidence="7" type="ORF">A0J61_07755</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the universal ribosomal protein uL18 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000543">
        <property type="protein sequence ID" value="OBZ84194.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NA23"/>
    <dbReference type="FunCoup" id="A0A1C7NA23">
        <property type="interactions" value="584"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NA23"/>
    <dbReference type="InParanoid" id="A0A1C7NA23"/>
    <dbReference type="OrthoDB" id="1618453at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022625">
        <property type="term" value="C:cytosolic large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008097">
        <property type="term" value="F:5S rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000027">
        <property type="term" value="P:ribosomal large subunit assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00432">
        <property type="entry name" value="Ribosomal_L18_L5e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd22852">
        <property type="entry name" value="SMN_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.100:FF:000002">
        <property type="entry name" value="60S ribosomal protein L5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01337_A">
        <property type="entry name" value="Ribosomal_uL18_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005485">
        <property type="entry name" value="Rbsml_uL18_euk_arch"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057268">
        <property type="entry name" value="Ribosomal_L18"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047313">
        <property type="entry name" value="SMN_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23410:SF12">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN UL18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23410">
        <property type="entry name" value="RIBOSOMAL PROTEIN L5-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17144">
        <property type="entry name" value="Ribosomal_L5e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20635">
        <property type="entry name" value="SMN_YG-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00058">
        <property type="entry name" value="RIBOSOMALL5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53137">
        <property type="entry name" value="Translational machinery components"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4 7" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="42"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="95"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="6">
        <location>
            <begin position="113"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="402"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007116"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OBZ84194.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="402" mass="45914" checksum="63A10E44918AA9F1" modified="2016-11-30" version="1" fragment="single">MRLYQVMSLVQDPDQVTADLIKDLPLKPSLDASILAHEATEAKSLSNADEDQEPDASEPFPIQPLTESQLLHDQTTLIPEFIENQRVLEDNITTNEEKDTYPQSAYHEYSQPYPDPSFMQPPPIPPPSTTEEAELFSNVIMSWYYAGYYTAMYQPFVKQQKNKAYFKRYQVKYRRRREGKTDYYARKRLVVQAKNKYNSPKYRLVVRFTNKDIICQIIYAKLQGDHVLSAAYAHELPRYGVKGGLTNWASAYATGLLLARRTLTKLGLADKYEGFAEPDGTVQLIEAAEDAPRPFKAFLDVGLARTSTGARVFGAMKGASDGGIFVPHSGNRFPGFDIESKTNDDELLRNYIYGVHVAEYMEYLEEEDEERYKKQFSTFIKNGITSDMVEDMYTEAHEAIRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NAQ4</accession>
    <name>A0A1C7NAQ4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein C2F7.07c</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">A0J61_07488</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000507">
        <property type="protein sequence ID" value="OBZ84464.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NAQ4"/>
    <dbReference type="STRING" id="101091.A0A1C7NAQ4"/>
    <dbReference type="InParanoid" id="A0A1C7NAQ4"/>
    <dbReference type="OrthoDB" id="5876363at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032221">
        <property type="term" value="C:Rpd3S complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd15534">
        <property type="entry name" value="PHD2_PHF12_Rco1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052819">
        <property type="entry name" value="Chromatin_regulatory_protein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019786">
        <property type="entry name" value="Zinc_finger_PHD-type_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001965">
        <property type="entry name" value="Znf_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019787">
        <property type="entry name" value="Znf_PHD-finger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47636">
        <property type="entry name" value="TRANSCRIPTIONAL REGULATORY PROTEIN RCO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47636:SF1">
        <property type="entry name" value="TRANSCRIPTIONAL REGULATORY PROTEIN RCO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00628">
        <property type="entry name" value="PHD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00249">
        <property type="entry name" value="PHD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01359">
        <property type="entry name" value="ZF_PHD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50016">
        <property type="entry name" value="ZF_PHD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="PHD-type" evidence="6">
        <location>
            <begin position="23"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="242"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="242"/>
            <end position="263"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OBZ84464.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="360" mass="42203" checksum="28341E668A39F2C8" modified="2016-11-30" version="1">MDEIKRKDQRQLIKKTEKKHQNRDVCDACGGVGQFLCCDACPSAFHFTCVEPPMDSIDVANLKEKWFCNHCEHKQHKKARSHPKELFSELLEDLAQRNPKSFRLPMEITHFYKGVTQDKYGRYVDTTQYKRTKNAQLEQADYRLLKNKQGLIICYYCRKTSLKKQIIACDYCNLYWHLDCLNPPLAASPPLTKKWRCPHHIENLIKPRRHLRNPADVTIITYPTTPACAYQNYLDNLLEEDGEVEEQEGDDGEEKEEEEEDKEGTEMISSRREAEDVIVSQEGIAYRLPAKPIQFSNPISYEVETWLHNLACFKAGMPNDGLSLKKRKTREMDIETYQRYQLIDKLLKEKSDQELQDLYK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NB85</accession>
    <name>A0A1C7NB85_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">protein kinase C</fullName>
            <ecNumber evidence="2">2.7.11.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="22" type="primary">pkcA</name>
        <name evidence="22" type="ORF">A0J61_05597</name>
    </gene>
    <organism evidence="22 23">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="22 23" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="22 23">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.13"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.13"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="22">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.13" evidence="2"/>
    <dbReference type="EMBL" id="LUGH01000307">
        <property type="protein sequence ID" value="OBZ86353.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NB85"/>
    <dbReference type="FunCoup" id="A0A1C7NB85">
        <property type="interactions" value="227"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NB85"/>
    <dbReference type="InParanoid" id="A0A1C7NB85"/>
    <dbReference type="OrthoDB" id="63267at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004697">
        <property type="term" value="F:diacylglycerol-dependent serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106310">
        <property type="term" value="F:protein serine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd20822">
        <property type="entry name" value="C1_ScPKC1-like_rpt1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd20823">
        <property type="entry name" value="C1_ScPKC1-like_rpt2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd05570">
        <property type="entry name" value="STKc_PKC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000101">
        <property type="entry name" value="Protein kinase C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000103">
        <property type="entry name" value="Protein kinase C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.60.20:FF:000014">
        <property type="entry name" value="Protein kinase C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.60.20:FF:000064">
        <property type="entry name" value="Protein kinase C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.60.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.160">
        <property type="entry name" value="HR1 repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000961">
        <property type="entry name" value="AGC-kinase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046349">
        <property type="entry name" value="C1-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035892">
        <property type="entry name" value="C2_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011072">
        <property type="entry name" value="HR1_rho-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036274">
        <property type="entry name" value="HR1_rpt_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002219">
        <property type="entry name" value="PKC_DAG/PE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017892">
        <property type="entry name" value="Pkinase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24351">
        <property type="entry name" value="RIBOSOMAL PROTEIN S6 KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00130">
        <property type="entry name" value="C1_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02185">
        <property type="entry name" value="HR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00433">
        <property type="entry name" value="Pkinase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00109">
        <property type="entry name" value="C1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00742">
        <property type="entry name" value="Hr1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00133">
        <property type="entry name" value="S_TK_X"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49562">
        <property type="entry name" value="C2 domain (Calcium/lipid-binding domain, CaLB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57889">
        <property type="entry name" value="Cysteine-rich domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46585">
        <property type="entry name" value="HR1 repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51285">
        <property type="entry name" value="AGC_KINASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51860">
        <property type="entry name" value="REM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00479">
        <property type="entry name" value="ZF_DAG_PE_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50081">
        <property type="entry name" value="ZF_DAG_PE_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12 16" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="15" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="10" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8 16" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="23" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="11" id="KW-0862">Zinc</keyword>
    <keyword evidence="9" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="REM-1" evidence="21">
        <location>
            <begin position="85"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="domain" description="Phorbol-ester/DAG-type" evidence="19">
        <location>
            <begin position="363"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="domain" description="Phorbol-ester/DAG-type" evidence="19">
        <location>
            <begin position="430"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="18">
        <location>
            <begin position="651"/>
            <end position="910"/>
        </location>
    </feature>
    <feature type="domain" description="AGC-kinase C-terminal" evidence="20">
        <location>
            <begin position="911"/>
            <end position="981"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="500"/>
            <end position="525"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="558"/>
            <end position="579"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="593"/>
            <end position="625"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="17">
        <location>
            <begin position="564"/>
            <end position="574"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="17">
        <location>
            <begin position="593"/>
            <end position="612"/>
        </location>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="680"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00047272"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00047470"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01207"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="PROSITE" id="PS50081"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="PROSITE" id="PS51285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="21">
        <source>
            <dbReference type="PROSITE" id="PS51860"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="EMBL" id="OBZ86353.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="982" mass="111827" checksum="3641CE0E751E275F" modified="2016-11-30" version="1">MRDKAYQLKPLLTDRNALSQCETEIRECQKYIDYFTEELAKITSKGDVEDTVIPSDTAIANRVRASSVGATEGHGKKYSTLDLLTTETLFSKSKVSMKLHELEYKLDVENKVLAGIKTMADVLDRDSSASDRRRRTELQGQMYESIEKLSLLTKALRKYKSLYIGEGDDEDDELETPPSARMPPDTIIYVKVDGNVVFRSKPSRNDKWLDICETHVNKATEVEISIYDQEAERSLPIGIFWLKITDIAEGLRKKKIQQENGSGWVPADVYQQQEQQTGSNYAIAGHGSNTTAVADQQVPQPQEPNYIESTQDGIQAWFDVEPSGEMLLRVNFVREAANRRPLDKLGRAGAVRQRREEVHEMNGHQFFEKKFYNIMRCALCGEFLVNSGYQCEDCEYTCHKKCYTKVVTKCISKSNADKDADEDKLNHRIPHRFEPITNIGANWCCHCGYMLPLGSKGAKKCSECGITCHTKCQLFIPDFCGLSMEMANQMLAEIKAANKRKTLESTSSSSTSSKPNRASHPEDKLADGMSHLSLSQQKPLPQQPVSSLPQLSPVISTNRIQPTAPHPPVAPPHNQPYIPQQEQYPVQTSDPRYQQYQPMRPSLPSSAHSSPQLRPMHQYPSPGMDAVVRPAPASPMQAKPIQQRKVTLNDFNFLFVLGKGNFGKVMLAEDKYDKRLYAVKVLKKRFIIDNDEIESLRSEKRIFQAANRARHPFLIGLQSCFQTESRVYFVMEYVSGGDLMWHIQREPFSERRAKFYACEVLLALEYFHSQGIIYRDLKLDNIMLGLDGHIKVADYGLCKENMWYEETTGTFCGTPEFMAPEILLEQKYGRAVDWWAFGVLVYEMLLGQSPFRGEDEDEIFDAILEDEILYPVNMSRDSVSICQRLLNRDPKRRLGAGPTDAAEIKEHPFFHGVNWDDMLNKRVPPPFCPSITSPLDTSNFDEEFTRERPALTPINSLLNRVEQQEFQNFSYVADWTHAGPMF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NBD3</accession>
    <name>A0A1C7NBD3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_05886</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000332">
        <property type="protein sequence ID" value="OBZ86059.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NBD3"/>
    <dbReference type="InParanoid" id="A0A1C7NBD3"/>
    <dbReference type="OrthoDB" id="5340906at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ86059.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="85" mass="10046" checksum="5DA100B18DE2CAFE" modified="2016-11-30" version="1">MYPRLPRLHPTLEASFNRLEEKNKWLLSTGKVVEDTLYKFSKSCIVDRPSCSMILHLDDKTYLKEKLFTQEETTEMKQKKPPLNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NC06</accession>
    <name>A0A1C7NC06_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Mitochondrial fission process protein 1</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">Mitochondrial 18 kDa protein</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">Mtfp1</name>
        <name evidence="5" type="ORF">A0J61_05419</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the MTFP1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000291">
        <property type="protein sequence ID" value="OBZ86528.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NC06"/>
    <dbReference type="STRING" id="101091.A0A1C7NC06"/>
    <dbReference type="InParanoid" id="A0A1C7NC06"/>
    <dbReference type="OrthoDB" id="424969at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000266">
        <property type="term" value="P:mitochondrial fission"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019560">
        <property type="entry name" value="Mitochondrial_18_kDa_protein"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11001">
        <property type="entry name" value="MITOCHONDRIAL FISSION PROCESS PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11001:SF2">
        <property type="entry name" value="MITOCHONDRIAL FISSION PROCESS PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10558">
        <property type="entry name" value="MTP18"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="182"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="198"/>
            <end position="210"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00017835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00029631"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OBZ86528.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="210" mass="23044" checksum="147CBEAF1A9465AB" modified="2016-11-30" version="1">MTEHESLTDRVMEGKVDSLEGNARYLAYGARLRTAFMASSRYLAYTSEVGEAFRPIAPPALVTAAYGVSWLYLGGDVAYEGYKAAHADQSNAVIATTVVKRGIFQSLASMLAPAFAVHSIVKYSAYAFKNVKNPKVKGWGPSVLGLSIVPLLPYLFDEPIEHVVDAVFKPIEEKISKQVVPRLGHNKTGDDLPTEQQIEAKEQLDKKINK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NCQ5</accession>
    <name>A0A1C7NCQ5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Cyclin pch1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">pch1_0</name>
        <name evidence="4" type="ORF">A0J61_06804</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the cyclin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000428">
        <property type="protein sequence ID" value="OBZ85144.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NCQ5"/>
    <dbReference type="FunCoup" id="A0A1C7NCQ5">
        <property type="interactions" value="594"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NCQ5"/>
    <dbReference type="InParanoid" id="A0A1C7NCQ5"/>
    <dbReference type="OrthoDB" id="25002at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016538">
        <property type="term" value="F:cyclin-dependent protein serine/threonine kinase regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.10">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013763">
        <property type="entry name" value="Cyclin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036915">
        <property type="entry name" value="Cyclin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043198">
        <property type="entry name" value="Cyclin/Ssn8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006671">
        <property type="entry name" value="Cyclin_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10026">
        <property type="entry name" value="CYCLIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00134">
        <property type="entry name" value="Cyclin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF028758">
        <property type="entry name" value="Cyclin, C/H/G types"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00385">
        <property type="entry name" value="CYCLIN"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47954">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0195">Cyclin</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cyclin-like" evidence="3">
        <location>
            <begin position="37"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="domain" description="Cyclin-like" evidence="3">
        <location>
            <begin position="150"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="242"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="242"/>
            <end position="254"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU000383"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00385"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OBZ85144.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="263" mass="30258" checksum="5E4CC6B322E3EDBC" modified="2016-11-30" version="1">MTTQQWYFTKGELHDTPTILDGRTFEQEQIDRLKGCHYLLSVGAKLALPQLVVVTASTYFHRFFMRQSMSRFHVYEIAATCLFVATKVEECTRRLKDIVLACAQKSQKNDKLRLEENSKDFIRWKELMLYNEIIVLETLCFDLSVEHPQLRLLELETQLKVQPSSVRKAWTLLYQSLGAPLCVLYKPKLVAAAALLLATNLSSSEKLNESWTETFDDVDVGQIYELAAEMLEHYMEHYLQKSSSSSQANSPHPSQLHHTTNGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NDC9</accession>
    <name>A0A1C7NDC9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Dilute domain-containing protein C25B8.08</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">A0J61_04865</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000248">
        <property type="protein sequence ID" value="OBZ87085.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NDC9"/>
    <dbReference type="STRING" id="101091.A0A1C7NDC9"/>
    <dbReference type="InParanoid" id="A0A1C7NDC9"/>
    <dbReference type="OrthoDB" id="426293at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051020">
        <property type="term" value="F:GTPase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd15473">
        <property type="entry name" value="Myo5p-like_CBD_DIL_ANK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002710">
        <property type="entry name" value="Dilute_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037986">
        <property type="entry name" value="Myo5p-like_CBD_DIL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052072">
        <property type="entry name" value="Vascular_dev_regulator"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16027:SF6">
        <property type="entry name" value="DILUTE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16027">
        <property type="entry name" value="DILUTE DOMAIN-CONTAINING PROTEIN YPR089W"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00023">
        <property type="entry name" value="Ank"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01843">
        <property type="entry name" value="DIL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM01132">
        <property type="entry name" value="DIL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51126">
        <property type="entry name" value="DILUTE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="repeat" description="ANK" evidence="1">
        <location>
            <begin position="113"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="1">
        <location>
            <begin position="146"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="domain" description="Dilute" evidence="3">
        <location>
            <begin position="369"/>
            <end position="618"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="265"/>
            <end position="292"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OBZ87085.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="738" mass="83769" checksum="1AE949D614BEEED8" modified="2016-11-30" version="1">MTEQKEIFTVSQDTFGLQKKYESMSIEEMSQYLAESNKQMSKMLNATVTNTSSYSELTTSAENEANGQQSDPHKKWTALFVRSASNGDVEKMKEILADESIRPLVDINAPDNDGTPPLIYAACFGKVEVAQVLIEAGANINAQDSFGWSALMWATNNSHESLVKILLDHGASAQTRSAKGRTVFDFVNTENQKMVDILATNPRDSVSSTSSILYKTSSSISSFSSAGDHDFYYHSTPDGYDQFMSEEAELRKKLFESTMALTLNTIDSNETQTDEDDDHAQGGSVRDQEDEDTESLFEENVFHWDRCSPDQMFVFNSDNLDHILDTAITQIQLPLTDQNDIHVPSNIIFLCARFAHYFSTPDLLEQVLEGALSRISSIVKKDTGLIAATAEQQLNLSESISEVYNLMIQDTEKRLGKLLPALLDHEEIPGINQVDFADDWHRFFRKNARQSMMVSLDSTVTPPTSAISPQSITGLLSSILFVFHSYDVHPIIVVQSLAQFFHYLSCEIFNRILTNKKLLCRSRAMQVRMNFSHLEDWVSINRLPNSLLAYLNPTIQLLQLLQCVTHLRELMDFINTTREFDTLNAIQIKRCVLSYRYEVDEDHIPEEIEKYAMQCAEDTVRHKLRKARQSIIMTPSRSDSIPTAAKRQSMSQFLGLYRNASSTSVLEQSLEEQKHSLDDTIYEEDEDDSNSDINETRDSKFLLPFSIPTSAHMNNSFHEENHIIPIIPEEWMEKLDKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NDD6</accession>
    <name>A0A1C7NDD6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Acyl-coenzyme A oxidase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="19" type="primary">ACX1.2_0</name>
        <name evidence="19" type="ORF">A0J61_04850</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="19 20" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19 20">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a 2,3-saturated acyl-CoA + O2 = a (2E)-enoyl-CoA + H2O2</text>
            <dbReference type="Rhea" id="RHEA:38959"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16240"/>
            <dbReference type="ChEBI" id="CHEBI:58856"/>
            <dbReference type="ChEBI" id="CHEBI:65111"/>
            <dbReference type="EC" id="1.3.3.6"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="4">Lipid metabolism; peroxisomal fatty acid beta-oxidation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Peroxisome</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5 12">Belongs to the acyl-CoA oxidase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="19">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000247">
        <property type="protein sequence ID" value="OBZ87095.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NDD6"/>
    <dbReference type="STRING" id="101091.A0A1C7NDD6"/>
    <dbReference type="InParanoid" id="A0A1C7NDD6"/>
    <dbReference type="OrthoDB" id="538336at2759"/>
    <dbReference type="UniPathway" id="UPA00661"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005777">
        <property type="term" value="C:peroxisome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003997">
        <property type="term" value="F:acyl-CoA oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005504">
        <property type="term" value="F:fatty acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033540">
        <property type="term" value="P:fatty acid beta-oxidation using acyl-CoA oxidase"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055088">
        <property type="term" value="P:lipid homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.140.10:FF:000005">
        <property type="entry name" value="Acyl-coenzyme A oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.140.10:FF:000013">
        <property type="entry name" value="Acyl-coenzyme A oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.110.10:FF:000003">
        <property type="entry name" value="Acyl-coenzyme A oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.540.10">
        <property type="entry name" value="Acyl-CoA dehydrogenase/oxidase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.110.10">
        <property type="entry name" value="Butyryl-CoA Dehydrogenase, subunit A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.140.10">
        <property type="entry name" value="Butyryl-CoA Dehydrogenase, subunit A, domain 3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055060">
        <property type="entry name" value="ACOX_C_alpha1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029320">
        <property type="entry name" value="Acyl-CoA_ox_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006091">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046373">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012258">
        <property type="entry name" value="Acyl-CoA_oxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002655">
        <property type="entry name" value="Acyl-CoA_oxidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036250">
        <property type="entry name" value="AcylCo_DH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037069">
        <property type="entry name" value="AcylCoA_DH/ox_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009100">
        <property type="entry name" value="AcylCoA_DH/oxidase_NM_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10909">
        <property type="entry name" value="ELECTRON TRANSPORT OXIDOREDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10909:SF250">
        <property type="entry name" value="PEROXISOMAL ACYL-COENZYME A OXIDASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01756">
        <property type="entry name" value="ACOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22924">
        <property type="entry name" value="ACOX_C_alpha1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02770">
        <property type="entry name" value="Acyl-CoA_dh_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14749">
        <property type="entry name" value="Acyl-CoA_ox_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000168">
        <property type="entry name" value="Acyl-CoA_oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47203">
        <property type="entry name" value="Acyl-CoA dehydrogenase C-terminal domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56645">
        <property type="entry name" value="Acyl-CoA dehydrogenase NM domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 12 14" id="KW-0274">FAD</keyword>
    <keyword evidence="8" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="6 12" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="10" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-0576">Peroxisome</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Acyl-coenzyme A oxidase N-terminal" evidence="17">
        <location>
            <begin position="35"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA oxidase/dehydrogenase middle" evidence="16">
        <location>
            <begin position="151"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA oxidase C-alpha1" evidence="18">
        <location>
            <begin position="292"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA oxidase C-terminal" evidence="15">
        <location>
            <begin position="504"/>
            <end position="682"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="13">
        <location>
            <position position="445"/>
        </location>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="155"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="194"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004275"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00006288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRNR" id="PIRNR000168"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR000168-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PIRSR" id="PIRSR000168-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF01756"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF02770"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF14749"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="Pfam" id="PF22924"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="OBZ87095.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="699" mass="79095" checksum="867F48DF5C21F3C1" modified="2016-11-30" version="1">MTFNNAVPTKFPDLKPRVPGGEALLAAERANTTFDINALSKFMYTKPWLDSMNKILQVIENELAFDKSKRYFQSRQEKITTGLQKDRRLVELVREHRWTEEEAQIANFLYDQSTPFSLHYGMFIPTLKNQTTDEQKRLFLEPALRHEIIGCYAQTELGHGSNVQGLETTATYIPETNEFEIHSPTLTSCKWWIGGLGKAANHAIVMARLITDGKDLGPHPFCVQIRSLEDHRPLPGITVGDIGPKFGFNATDNGFIMFDHYRVPHISFLAKYSQVKPGSGTYTKPPNAKLSYGTMVFVRANIVMGVRYALARATTVAIRYSTIRQQFVDATSPHKWNNQVVETPVLNYTMQQYRLLPIVAAAYACFFTGREMLRLYDLNQTAMQQGNYSLLADLHASSSGLKSLTTTMAIESLEDCRRACGGHGYSLFSGLGLFYQDYLPNVTWEGDNYILTQQTARYLLKTFRHVVAGKAEPSEYNHTITYLTSYLQNPKAKCPATSAEDFLNPETILSAFGFRAAYGIAQVAEQIDRHGRSWNSMLVEISRISKAHCQFVLVRNFLVTLQKDPSLILPENKPMLQVLKTLAYLFALNTIEKELSEFLLSGYLSSEQSVQLKQQVIALLEQVRPNAVGLVDAFALPDYYLNSALGRYDGKVYESMTKMAEDEPLNHTLVVDGYQENIKPFVHKQYKKKTNSRDSVSRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NE99</accession>
    <name>A0A1C7NE99_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">sphingomyelin phosphodiesterase</fullName>
            <ecNumber evidence="2">3.1.4.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">A0J61_04688</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the neutral sphingomyelinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.4.12" evidence="2"/>
    <dbReference type="EMBL" id="LUGH01000234">
        <property type="protein sequence ID" value="OBZ87270.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NE99"/>
    <dbReference type="STRING" id="101091.A0A1C7NE99"/>
    <dbReference type="InParanoid" id="A0A1C7NE99"/>
    <dbReference type="OrthoDB" id="40902at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004767">
        <property type="term" value="F:sphingomyelin phosphodiesterase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd09078">
        <property type="entry name" value="nSMase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.10.10">
        <property type="entry name" value="Endonuclease/exonuclease/phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036691">
        <property type="entry name" value="Endo/exonu/phosph_ase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005135">
        <property type="entry name" value="Endo/exonuclease/phosphatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038772">
        <property type="entry name" value="Sph/SMPD2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017766">
        <property type="entry name" value="Sphingomyelinase/PLipase_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16320:SF1">
        <property type="entry name" value="SPHINGOMYELINASE DDB_G0288017"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16320">
        <property type="entry name" value="SPHINGOMYELINASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03372">
        <property type="entry name" value="Exo_endo_phos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56219">
        <property type="entry name" value="DNase I-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="168"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="domain" description="Endonuclease/exonuclease/phosphatase" evidence="6">
        <location>
            <begin position="213"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="33"/>
            <end position="42"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012369"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF03372"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OBZ87270.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="553" mass="63568" checksum="DC89F6DD8DB94C54" modified="2016-11-30" version="1">MSSSVPAVPTVHQVNEEEEEETIDSPMPTEPYHDDDNEDTPEDNNNNRMLPQSSYEASVISVQSNPPPYELYPPAKTVFGRIFNWVRQIPQWNTHQPIYLPTIHNSNSSSGRSIFSLGRRHRRTDSTASSISSTESVSCWSYYYYAIKDRLPECPRFVLPSVLAKHRIGLIVLSVFCLVLFSFLLFCSVFFSSTDYPAPVFPDKVTNTTARFLTLNIFMRPPLIKNNWSDYKDDRLAYIEKYILPEYDVICFQESFAFASRRKDRLITTARQLGFNHHVESPRKYPWNIGVDGGLLILSRFPIRQADVIEYPRGQHSDWLSIKGALHAHIELNPTKKVHLYTTHTQASYDLNNVVNEDDTAIRLSQFAILHQFIYDTSRLNDNQDPIMVVGDLNVDAAIHPVDRPITQPSKESSSEYLKMVDVIRGVGAAKLNQSKDDRWFEHHWKLTNMTDVVYDHYGYHPVTFGDYLINEQGDLAPAETVLTNWDVLMTVQSIDRIFLATRNDTHTATLTQPRVEKFWVKENDQMSAEEKQKTGFTQISDHYGISCDIQVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NEG1</accession>
    <name>A0A1C7NEG1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_04449</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000218">
        <property type="protein sequence ID" value="OBZ87493.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NEG1"/>
    <dbReference type="InParanoid" id="A0A1C7NEG1"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="205"/>
            <end position="230"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ87493.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="230" mass="23137" checksum="95808C8117C3CB21" modified="2016-11-30" version="1">MNTSSYMEFLERIKLSSERKLEEMDGKKDTPILRQLQVQIIRWKAEVEYEEHVAFLSSSSPSSSSPSSVGPVPAGTTATTIVSVADAAATNAADSAVDASDASGSTSATTSAAVSAATSAAIVSSVSASAVAFLSAAGNDVIAAAISAAATAVNAAAIAAASIASVFDSVSAANTSINTICDATTAAANAANAATAASALTCDLPPVAPSPGKRKRKDDNHLQRKRQRLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NEJ7</accession>
    <name>A0A1C7NEJ7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Aspartate--tRNA ligase, cytoplasmic</fullName>
            <ecNumber evidence="3">6.1.1.12</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">Aspartyl-tRNA synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="primary">DPS1</name>
        <name evidence="14" type="ORF">A0J61_04460</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>tRNA(Asp) + L-aspartate + ATP = L-aspartyl-tRNA(Asp) + AMP + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:19649"/>
            <dbReference type="Rhea" id="RHEA-COMP:9660"/>
            <dbReference type="Rhea" id="RHEA-COMP:9678"/>
            <dbReference type="ChEBI" id="CHEBI:29991"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78516"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.12"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the class-II aminoacyl-tRNA synthetase family. Type 2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.12" evidence="3"/>
    <dbReference type="EMBL" id="LUGH01000219">
        <property type="protein sequence ID" value="OBZ87478.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NEJ7"/>
    <dbReference type="FunCoup" id="A0A1C7NEJ7">
        <property type="interactions" value="719"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NEJ7"/>
    <dbReference type="InParanoid" id="A0A1C7NEJ7"/>
    <dbReference type="OrthoDB" id="372395at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017101">
        <property type="term" value="C:aminoacyl-tRNA synthetase multienzyme complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004815">
        <property type="term" value="F:aspartate-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006422">
        <property type="term" value="P:aspartyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04320">
        <property type="entry name" value="AspRS_cyto_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00776">
        <property type="entry name" value="AsxRS_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.930.10:FF:000013">
        <property type="entry name" value="Aspartate--tRNA ligase, cytoplasmic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.140:FF:000132">
        <property type="entry name" value="Aspartyl-tRNA synthetase, cytoplasmic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="entry name" value="Bira Bifunctional Protein, Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02075">
        <property type="entry name" value="Asp_tRNA_synth_type2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004364">
        <property type="entry name" value="Aa-tRNA-synt_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006195">
        <property type="entry name" value="aa-tRNA-synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004523">
        <property type="entry name" value="Asp-tRNA_synthase_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002312">
        <property type="entry name" value="Asp/Asn-tRNA-synth_IIb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00458">
        <property type="entry name" value="aspS_nondisc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003483">
        <property type="entry name" value="PRK05159.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43450:SF1">
        <property type="entry name" value="ASPARTATE--TRNA LIGASE, CYTOPLASMIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43450">
        <property type="entry name" value="ASPARTYL-TRNA SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00152">
        <property type="entry name" value="tRNA-synt_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01042">
        <property type="entry name" value="TRNASYNTHASP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="Class II aaRS and biotin synthetases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50862">
        <property type="entry name" value="AA_TRNA_LIGASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 14" id="KW-0436">Ligase</keyword>
    <keyword evidence="7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aminoacyl-transfer RNA synthetases class-II family profile" evidence="13">
        <location>
            <begin position="243"/>
            <end position="540"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005312"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012841"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00018853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00033155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00047904"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="OBZ87478.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="548" mass="62396" checksum="2CEEA56EDD77D77B" modified="2016-11-30" version="1">MSAPAQDPVEDLTQKAKEIFLDDEGKPITKSAYKKLQKDKEKAERKAATAAKIAAEKAQREANNVDFSSDRYGKLPMNQSQTRTDTKYEDIDTINASREGETVTMRVRVQTSRATGGKMCFFVFRQNVSTIQGIITADEKTISKQMVKYCVGITPESIVLVQGKIVKPVEEVKSCTISDAELSIEKIHVVSEVNVRLAFSLEDATRPESSYEDQENQLARVNLDTRLNNRVLDLRTTTNHAIFRLQSAVGLLFREFLSERGFMEIHTPKLIGAASEGGSNVFKVSYFKTSAYLAQSPQLYKQMCIASDFGRVFEIAPVFRAEDSNTHRHMTEFMGLDMEMAFNEHYHEVLEVLEELFVYILTNLKARYQNEIDVVKKQYEFEDFEFLPKTLRLTFAEGIKMLREAGVEVDDFEDLSTANEKFLGKLVKEKYHTDFYVLDKFPLAVRPFYTMPDPNNPGYSNSYDFFWRGEEILSGAQRIHDPEFLTERAKEHGVDISTIQPYIDAFKIGAPPHAGGGIGLERVVMFYLGLGNIRRSSLFPRDPKRLEP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NFG9</accession>
    <name>A0A1C7NFG9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 5">Eukaryotic translation initiation factor 3 subunit E</fullName>
            <shortName evidence="4">eIF3e</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">int6</name>
        <name evidence="4" type="synonym">INT6</name>
        <name evidence="7" type="ORF">A0J61_04144</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4 5">Component of the eukaryotic translation initiation factor 3 (eIF-3) complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4 5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 5">Belongs to the eIF-3 subunit E family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000196">
        <property type="protein sequence ID" value="OBZ87808.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NFG9"/>
    <dbReference type="FunCoup" id="A0A1C7NFG9">
        <property type="interactions" value="1095"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NFG9"/>
    <dbReference type="InParanoid" id="A0A1C7NFG9"/>
    <dbReference type="OrthoDB" id="417252at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016282">
        <property type="term" value="C:eukaryotic 43S preinitiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033290">
        <property type="term" value="C:eukaryotic 48S preinitiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071540">
        <property type="term" value="C:eukaryotic translation initiation factor 3 complex, eIF3e"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001732">
        <property type="term" value="P:formation of cytoplasmic translation initiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd21378">
        <property type="entry name" value="eIF3E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.570">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03004">
        <property type="entry name" value="eIF3e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016650">
        <property type="entry name" value="eIF3e"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019010">
        <property type="entry name" value="eIF3e_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000717">
        <property type="entry name" value="PCI_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10317">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09440">
        <property type="entry name" value="eIF3_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21357">
        <property type="entry name" value="EIF3E_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01399">
        <property type="entry name" value="PCI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016255">
        <property type="entry name" value="eIF3e_su6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01186">
        <property type="entry name" value="eIF3_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00088">
        <property type="entry name" value="PINT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50250">
        <property type="entry name" value="PCI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 4 5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 4 5" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="3 4 5" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PCI" evidence="6">
        <location>
            <begin position="220"/>
            <end position="393"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRNR" id="PIRNR016255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50250"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OBZ87808.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="431" mass="50561" checksum="29E7FBC95E254221" modified="2016-11-30" version="1">MAAAQDLTLRMIPFLDRHLVFPLLEFLEVKEIYVLDDLLKAKYDLFKDSNMVDFVLDLYKKLHKTEETPKEFAEKREKVLSQMEELRAKAQQVMNVLEKPEVIAALRQDKAQNLQYLKDNYKFTDDSINILYEFGQFQYNCGDYGGAADYLYHYRVLSTDAERSLSATWGKMAAEILTGNWDAALEEMQKLREAIDQKNFTSPVQQLQQRTWLLHWSLFVFFNHPKGRDGIVDMFLTPQYINTIQTSCPWILRYLATAVVTNKRRKNQMKELVKIIEQEVYEYQDPVTEFVAALFVRFDFEGAQKKLKECEDVLSNDFFLAATHEDFMESARQFISETYCRIHQKIDIKQMSQRLNLSQEEGEKWIVNLIRDTRVDAKIDFEENTVIMNTPITSVYQQVIERTKGLSFRSQVLATTIKRREQQSASNEVVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NFK2</accession>
    <name>A0A1C7NFK2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_04202</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000200">
        <property type="protein sequence ID" value="OBZ87740.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NFK2"/>
    <dbReference type="InParanoid" id="A0A1C7NFK2"/>
    <dbReference type="OrthoDB" id="10638372at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="44"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="385"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="123"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="181"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="195"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="227"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="407"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="476"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ87740.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="476" mass="54668" checksum="EAA8F063E37AEA1C" modified="2016-11-30" version="1" fragment="single">MDANIRWSPNHALLSIVIEMLDTQPDLTDIDLLLHPSENDKVSHNKVIADQSESSLPEFSSDEPHSDLTLEDTTWNETTDDTSSDAAQIAATDTKEQPNQSDEEIYPDKVSLNKTKDAQSNPSDKEQNGSKMSDIRNEEEPHFEQPNQQYLPQEMAYQKNAKKAYPQLTELQSDQMQHQHKQQERQTCEPIEKGPSQSGWQQHANELNQERSSTSPQQSQAKKARKNREYLEQKKMFEEQYKQERIRQIQSQLQKDRLKKGQRYKELTEQQKQQLEQHNLTNQEIHAKPTPGILKTHKNHRGTSEQHKDMNNFIIDQKITQDHRHVSFNSVSTKNPNQSPVARQTSSYAFQNDFYHSSPEIEATAYKNSSIQQSNTFLDQRNRDYGKNLAKNGGSQNNSLARERNKPSSSETSSKLMQLDSQTEIEEAKSMEGTPSLGSSLDGKPDIFKLKQVFSQEIFKDDHEKAEKINAALTFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NGM1</accession>
    <name>A0A1C7NGM1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="14">Bifunctional purine biosynthesis protein ADE17</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">ADE17</name>
        <name evidence="14" type="ORF">A0J61_04262</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Bifunctional enzyme that catalyzes the last two steps of purine biosynthesis. Acts as a transformylase that incorporates a formyl group to the AMP analog AICAR (5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide) to produce the intermediate formyl-AICAR (FAICAR). Also catalyzes the cyclization of FAICAR to IMP.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>(6R)-10-formyltetrahydrofolate + 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide = 5-formamido-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide + (6S)-5,6,7,8-tetrahydrofolate</text>
            <dbReference type="Rhea" id="RHEA:22192"/>
            <dbReference type="ChEBI" id="CHEBI:57453"/>
            <dbReference type="ChEBI" id="CHEBI:58467"/>
            <dbReference type="ChEBI" id="CHEBI:58475"/>
            <dbReference type="ChEBI" id="CHEBI:195366"/>
            <dbReference type="EC" id="2.1.2.3"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>IMP + H2O = 5-formamido-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide</text>
            <dbReference type="Rhea" id="RHEA:18445"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
            <dbReference type="ChEBI" id="CHEBI:58467"/>
            <dbReference type="EC" id="3.5.4.10"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3">Purine metabolism; IMP biosynthesis via de novo pathway; 5-formamido-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide (10-formyl THF route): step 1/1.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2">Purine metabolism; IMP biosynthesis via de novo pathway; IMP from 5-formamido-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide: step 1/1.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytosol</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the PurH family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000204">
        <property type="protein sequence ID" value="OBZ87696.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NGM1"/>
    <dbReference type="FunCoup" id="A0A1C7NGM1">
        <property type="interactions" value="812"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NGM1"/>
    <dbReference type="InParanoid" id="A0A1C7NGM1"/>
    <dbReference type="OrthoDB" id="6017153at2759"/>
    <dbReference type="UniPathway" id="UPA00074">
        <property type="reaction ID" value="UER00133"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003937">
        <property type="term" value="F:IMP cyclohydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004643">
        <property type="term" value="F:phosphoribosylaminoimidazolecarboxamide formyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006189">
        <property type="term" value="P:'de novo' IMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd01421">
        <property type="entry name" value="IMPCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.140.20:FF:000003">
        <property type="entry name" value="Bifunctional purine biosynthesis protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1380:FF:000003">
        <property type="entry name" value="Bifunctional purine biosynthesis protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.440:FF:000001">
        <property type="entry name" value="Bifunctional purine biosynthesis protein PURH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.440">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.140.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1380">
        <property type="entry name" value="Methylglyoxal synthase-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00139">
        <property type="entry name" value="PurH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024051">
        <property type="entry name" value="AICAR_Tfase_dup_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024050">
        <property type="entry name" value="AICAR_Tfase_insert_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016193">
        <property type="entry name" value="Cytidine_deaminase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011607">
        <property type="entry name" value="MGS-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036914">
        <property type="entry name" value="MGS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002695">
        <property type="entry name" value="PurH-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF005492">
        <property type="entry name" value="PRK07106.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00355">
        <property type="entry name" value="purH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11692:SF0">
        <property type="entry name" value="BIFUNCTIONAL PURINE BIOSYNTHESIS PROTEIN ATIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11692">
        <property type="entry name" value="BIFUNCTIONAL PURINE BIOSYNTHESIS PROTEIN PURH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01808">
        <property type="entry name" value="AICARFT_IMPCHas"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02142">
        <property type="entry name" value="MGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000414">
        <property type="entry name" value="AICARFT_IMPCHas"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00798">
        <property type="entry name" value="AICARFT_IMPCHas"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00851">
        <property type="entry name" value="MGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53927">
        <property type="entry name" value="Cytidine deaminase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52335">
        <property type="entry name" value="Methylglyoxal synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51855">
        <property type="entry name" value="MGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="7" id="KW-0658">Purine biosynthesis</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="MGS-like" evidence="13">
        <location>
            <begin position="1"/>
            <end position="145"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004514"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004844"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007667"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00050488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00050687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00054363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51855"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="OBZ87696.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="588" mass="64432" checksum="4403B56F26BFB9F9" modified="2016-11-30" version="1">MSQKIAILSVYDKTGLLDFAKELHALNVRLLGSGGTAKLVREAGIPIGDVSEITKAPEMLGGRVKTLHPAVHGGILARNIESDEKDLAEQQIQKIDIVVCNLYPFKETIAKPDVTIPQAVEEVDIGGVTLLRAAAKNHARVSIVSDPSDYSKVIAELKDGQVSQETRNLLALKAFNHTADYDTAISDYFRRQYAKDQAMMPLRYGANPHQSPAQIYVKEGKLPVEVLSGSPGYINFLDALNSWALVKELKEATGVAGAASFKHVSPAGAAIGLPLSEVDQKVYQVDDLKVPLTPLANAYARARGADRMSSFGDFIGLSDVVDVATAKIISREVSDGVIAPGYEPEALEILRAKKGGKYCVLKMDANYEPEQQEIRQVYGLYLEQKRNSYKINASLFTNVVSKNKNLPKEAVNDLIVATIALKYTQSNSVCYAKNGMVIGLGAGQQSRIHCTRLAGDKADNWWLRHHPKVLAFDFKKGTKRADKSNAIDLYVTNQTGEGVEREAWEAFFNTVPEPLTAEERKEWMSKLADTVVSSDAFFPFSDNIYRAHRSGVKYIAAPSGSVQDEAVIAAADNNDMVMAHTNLRLFHH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NGS5</accession>
    <name>A0A1C7NGS5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Probable 26S proteasome regulatory subunit p27</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">PSMD9</name>
        <name evidence="6" type="ORF">A0J61_05361</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the proteasome subunit p27 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000287">
        <property type="protein sequence ID" value="OBZ86584.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NGS5"/>
    <dbReference type="FunCoup" id="A0A1C7NGS5">
        <property type="interactions" value="798"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NGS5"/>
    <dbReference type="InParanoid" id="A0A1C7NGS5"/>
    <dbReference type="OrthoDB" id="72325at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000502">
        <property type="term" value="C:proteasome complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070682">
        <property type="term" value="P:proteasome regulatory particle assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.42.10:FF:000107">
        <property type="entry name" value="26S proteasome non-ATPase regulatory subunit 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.42.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.1710">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040815">
        <property type="entry name" value="Nas2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001478">
        <property type="entry name" value="PDZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041489">
        <property type="entry name" value="PDZ_6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036034">
        <property type="entry name" value="PDZ_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035269">
        <property type="entry name" value="PSMD9"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12651">
        <property type="entry name" value="26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12651:SF1">
        <property type="entry name" value="26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18265">
        <property type="entry name" value="Nas2_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17820">
        <property type="entry name" value="PDZ_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00228">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50156">
        <property type="entry name" value="PDZ domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0143">Chaperone</keyword>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-0647">Proteasome</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PDZ" evidence="5">
        <location>
            <begin position="127"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="20"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005256"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00068021"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00228"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OBZ86584.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="226" mass="25014" checksum="696CF7A9103D4F93" modified="2016-11-30" version="1">MGLMPPAINEPTTPSLEPTIDELMGEAKQLITRKDKIEEELRELEDLLISAGVGMDEPLVDSAGFPRSEIDVHSIRTSRNMIHRLRNDHRSVMTDIEKVLHKIHEAKRNEKQQEEEEEATTSTVAPPTASVVIQEVPVAFAIVNAVAPDSPADSAGLRRNDQIFKFGHINSTNHERLQALYGLISRSENHQVTVSVLREGQTIDIVVTPRSGWGGRGTLGCHLLPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NHH1</accession>
    <name>A0A1C7NHH1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Bypass of stop codon protein 6</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">BSC6</name>
        <name evidence="9" type="ORF">A0J61_03377</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000144">
        <property type="protein sequence ID" value="OBZ88573.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NHH1"/>
    <dbReference type="STRING" id="101091.A0A1C7NHH1"/>
    <dbReference type="InParanoid" id="A0A1C7NHH1"/>
    <dbReference type="OrthoDB" id="413079at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000286">
        <property type="entry name" value="MFS efflux transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051788">
        <property type="entry name" value="MFS_Transporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23514">
        <property type="entry name" value="BYPASS OF STOP CODON PROTEIN 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23514:SF3">
        <property type="entry name" value="BYPASS OF STOP CODON PROTEIN 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="36"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="70"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="101"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="126"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="159"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="185"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="239"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="282"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="305"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="333"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="365"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="390"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="8">
        <location>
            <begin position="35"/>
            <end position="417"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OBZ88573.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="424" mass="45773" checksum="448F9B2894B207B4" modified="2016-11-30" version="1">MVNQVERTLEAEPLLNTQQAKSEESFQDLKGHIKPLLSAFFISIVAGLNDGSLGAIIPRLKQYYNVPNETISLLFLCSAFGFFLSAGLNGYIVHRIGQLNTLYLGSCTMFVSFAILSAGFPFPVMAITMPFVGAGMALLDAAMNVFVANLPLATLMLNILHAIYGVGAMISPLVASVLLEHDISWTGMYLFLTAVGLLNVISIATGFKGVKLEEHKDEDGDDNKPGHRELTRLAIFNKVTLICAVYILVYVGVEVTLGGWGYTFLREGRGGDKVDMARVVSGYWAGLASGRILLGYLSSRFGEKLMISLFTMMIIAGLFLMMVYKNIVLNSTVFITLGLLLGPMFPTTVSLASKALPRSYHATSIGFMAALGAGGAALFPFLTGQVAGQYGILIMPIACIIMSVVMLLLWVFIPSDKPLFAACQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-06-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NHN2</accession>
    <name>A0A1C7NHN2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_03462</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000149">
        <property type="protein sequence ID" value="OBZ88490.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NHN2"/>
    <dbReference type="InParanoid" id="A0A1C7NHN2"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ88490.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="69" mass="8440" checksum="E21EC4C5BD2859C7" modified="2016-11-30" version="1">MEIRLCRLYYQLRKHEKLFEVDVNQEYVKIKKEKLLLAKCRNSTYDRTSPQNKVIMYFGVELLNLEKEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NHR2</accession>
    <name>A0A1C7NHR2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Amino acid transporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">gltT</name>
        <name evidence="10" type="ORF">A0J61_03427</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="8">Membrane</location>
            <topology evidence="8">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000147">
        <property type="protein sequence ID" value="OBZ88520.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NHR2"/>
    <dbReference type="STRING" id="101091.A0A1C7NHR2"/>
    <dbReference type="InParanoid" id="A0A1C7NHR2"/>
    <dbReference type="OrthoDB" id="5877963at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015293">
        <property type="term" value="F:symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006835">
        <property type="term" value="P:dicarboxylic acid transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.3860.10:FF:000001">
        <property type="entry name" value="C4-dicarboxylate transport protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3860.10">
        <property type="entry name" value="Sodium:dicarboxylate symporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001991">
        <property type="entry name" value="Na-dicarboxylate_symporter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036458">
        <property type="entry name" value="Na:dicarbo_symporter_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42865">
        <property type="entry name" value="PROTON/GLUTAMATE-ASPARTATE SYMPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42865:SF7">
        <property type="entry name" value="PROTON_GLUTAMATE-ASPARTATE SYMPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00375">
        <property type="entry name" value="SDF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00173">
        <property type="entry name" value="EDTRNSPORT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF118215">
        <property type="entry name" value="Proton glutamate symport protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0769">Symport</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2 8" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="103"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="134"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="168"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="236"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="322"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU361216"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OBZ88520.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="546" mass="59269" checksum="421BC928E356BE86" modified="2016-11-30" version="1">MDEITSHKDTSANNDHHTPNEKLQAGSFTEDVNAARDDASSIRYRNQSVGRDHIPEHLRIPPVENAGYSPRISNVGKQINDAFLFAIAPLIKLIRFLNRRTNLSFWIIVSMVVGILIGNFAPAFGKEIKPLGDAFIMMIKICIVPLVFSVLVIGIAGHGDDIGKVGKLAIKTLIYFEVVTTLALALGLIMANLVKPGQGVSLPVGSDISSVQELADKEKTSITWSGELFMIIPENFFVAAVNNKVLAIVFCAVLFACAMMKADKKSKKFMLQINESLSQVMFQYVALIMRYAPIGIGSALAATVGSNGISVLANLGKLIGCLYASLVIFLIVVLVPIMFLAKIPIIGFFKAIAQPWLLAFSSASSESALPLAFDRMREFGCPNSLTGFVIPCGYSFNLDGTTLYLSLATIFSAQAAGLNLPLATQMSIMGTLMLSSKGVAAIPRASLVVLSGTLAQYNIPLEAVLMIMGVDAIMDMARTSLNVFGNCLGCCVMARVEGSFRGEEWRQEEEDRRYKKWLDEQEKAGLLDRETSDLSGVVIHNETKAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NHS4</accession>
    <name>A0A1C7NHS4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Developmental regulator flbA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">flbA_2</name>
        <name evidence="4" type="ORF">A0J61_03389</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000144">
        <property type="protein sequence ID" value="OBZ88568.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NHS4"/>
    <dbReference type="FunCoup" id="A0A1C7NHS4">
        <property type="interactions" value="15"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NHS4"/>
    <dbReference type="InParanoid" id="A0A1C7NHS4"/>
    <dbReference type="OrthoDB" id="196547at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035556">
        <property type="term" value="P:intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009968">
        <property type="term" value="P:negative regulation of signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.167.10">
        <property type="entry name" value="Regulator of G-protein Signalling 4, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000591">
        <property type="entry name" value="DEP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016137">
        <property type="entry name" value="RGS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058855">
        <property type="entry name" value="RGS1/SST2-like_Fungal-DR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036305">
        <property type="entry name" value="RGS_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044926">
        <property type="entry name" value="RGS_subdomain_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10845:SF192">
        <property type="entry name" value="DOUBLE HIT, ISOFORM B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10845">
        <property type="entry name" value="REGULATOR OF G PROTEIN SIGNALING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00615">
        <property type="entry name" value="RGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25889">
        <property type="entry name" value="WHD_Fungal_DR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00049">
        <property type="entry name" value="DEP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00315">
        <property type="entry name" value="RGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48097">
        <property type="entry name" value="Regulator of G-protein signaling, RGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50132">
        <property type="entry name" value="RGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0734">Signal transduction inhibitor</keyword>
    <feature type="domain" description="RGS" evidence="3">
        <location>
            <begin position="441"/>
            <end position="595"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="206"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="400"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="208"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="408"/>
            <end position="431"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022700"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50132"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OBZ88568.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="635" mass="71395" checksum="A5A89A5447AB9C05" modified="2016-11-30" version="1">MDSNISQQAYTSMVKFTIDGRPFLKDIHDLFSALIVQIPLDTHRYLFRNYYNTFSSEDAIQVLGNLQFSHTVRTPDPSDPSRTQCTTTTTTFNMARDMAKSLCQHFQNCRLMENAVDPQNRTFRDKGIWHLTPKGLCVLQDFCVRTEANINTLRKHFSHMDAIQLVRLDRNSDDDQLIVNRASASLVFRVMMMTLPLDGELSNMGNASSISVSSRQQSNSTPPSSSSSTSSATSSSSPSLSAPFAMSSSVSSGDSRVQLLGNYLLTLSKSNRTQPKTVKTMRTVFSSQMCSDWLVDYTTVSGREEAEVIVQDFVKYDWVEFQDAKYQNTPIKSSKVIMLLVTEKGKQIVSETTSLTTSLDRSKASQIHSGTFSKEEENEASLKEILSEDPETILTTTTTLKEEERTAPENNLLLSTSESQPRPSSIATDSVQDPKESNSARLKIILENAKLRSPFKDFLRANFCEENLDFWIDYTTLQRKCKNQSPALPTQNQKDLLEDAYDIWSTYLAPGSPSELNVEHSLLQEMARVINSVVTVLPAYPGQGKPTIVITASSASQSLRMMLKLFDRANEHICRLMASDSVPKFVKTEKYRKTIESIEKSERKKQKELDELADSLLNMGNNEDIHHANNIETRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NHV2</accession>
    <name>A0A1C7NHV2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein C30D11.11</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">A0J61_03222</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000135">
        <property type="protein sequence ID" value="OBZ88722.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NHV2"/>
    <dbReference type="InParanoid" id="A0A1C7NHV2"/>
    <dbReference type="OrthoDB" id="5585746at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0038023">
        <property type="term" value="F:signaling receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006882">
        <property type="term" value="P:intracellular zinc ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004254">
        <property type="entry name" value="AdipoR/HlyIII-related"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20855:SF97">
        <property type="entry name" value="ADIPOR-LIKE RECEPTOR IZH3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20855">
        <property type="entry name" value="ADIPOR/PROGESTIN RECEPTOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03006">
        <property type="entry name" value="HlyIII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="151"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="181"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="221"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="250"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="276"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="308"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="349"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="202"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="348"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="352"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR604254-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OBZ88722.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="382" mass="43638" checksum="41CE2CAAC8FA5F68" modified="2016-11-30" version="1">MAPPQLVEQPLLDEGFFSTNLHLRRYSQSHVVSTSSTKDALXIPRTRGRSSSTSVVQGSSLAAQILATVNNKLKEEPYTESDFISYMDNQVHETWETAKALMLGSKRLLLIEELPKDRQENQYVLSGYRFYRSTRECLKSLFRLHNETMNIWSHLLGFFFFSYLSIHVFQRKFPGASNRDLLMFSAFSVASLTCLLCSSIYHTFICHSARHVKSFTATLDYIGITFLITASISIVVHFGFYCDPIPRNRYIIFSCLIGSIGVILPFFRFFDTRRYRPLRIGLFVAMAFSSVVPLLHMTTVKGVSNTAAFLKPALLGSAMYVCGVTVYGKRFPEKFFPGKFDAAGMTSHAIWHIFVCLGIFFYYIGSFHFYNLREEYGCMLSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NI23</accession>
    <name>A0A1C7NI23_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Magnesium transporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">mrs2</name>
        <name evidence="13" type="ORF">A0J61_03176</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 12">Mitochondrion inner membrane</location>
            <topology evidence="1 12">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 12">Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000132">
        <property type="protein sequence ID" value="OBZ88777.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NI23"/>
    <dbReference type="FunCoup" id="A0A1C7NI23">
        <property type="interactions" value="287"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NI23"/>
    <dbReference type="InParanoid" id="A0A1C7NI23"/>
    <dbReference type="OrthoDB" id="10251508at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015095">
        <property type="term" value="F:magnesium ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045016">
        <property type="term" value="P:mitochondrial magnesium ion transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd12823">
        <property type="entry name" value="Mrs2_Mfm1p-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.128.330:FF:000002">
        <property type="entry name" value="Inner membrane magnesium transporter mrs2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.128.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.340">
        <property type="entry name" value="Magnesium transport protein CorA, transmembrane region"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039204">
        <property type="entry name" value="MRS2-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13890:SF0">
        <property type="entry name" value="MAGNESIUM TRANSPORTER MRS2 HOMOLOG, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13890">
        <property type="entry name" value="RNA SPLICING PROTEIN MRS2, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22099">
        <property type="entry name" value="MRS2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 12" id="KW-0406">Ion transport</keyword>
    <keyword evidence="6 12" id="KW-0460">Magnesium</keyword>
    <keyword evidence="11 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5 12" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="4 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 12" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="315"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="345"/>
            <end position="366"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009765"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU366042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="OBZ88777.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="378" mass="43154" checksum="C0F6B783A779B732" modified="2016-11-30" version="1">MHRTLPRISTFLCRQRLFQPIRCKRYETTFSDTATLINSSRRVVSIPSKMNEMKLRCTEFDQTGAVKTTAGEFLKSDFCQHHSLLPRDLRTIDTYSIYQKPTILVRPEAILVNMAHLKALIKSDMVVLFDTFGSADSYNQSIFIYDLQERLKSQKDGLPFEFRALEAILISVTSSLQSELDILDGPVNKILSDLEDLADIEESMNGDKLRDLLQYSKKLSKFEQDALSIRDVLEEVLDNDDDLAAMYLSDKQSGRPRAPSEHEEIELLLEAYYKQTEEIAAKAETLRQHMRSTEEIIQLLLDVSRNSLMWYDIRLTIITLSATVVSGFGAIFGMNLRNYFEDDPYAFGVVSGLAMMSGLGAFAIAVKKLRRFSKLKHK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NIG6</accession>
    <name>A0A1C7NIG6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Coactosin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">coaA</name>
        <name evidence="7" type="ORF">A0J61_03037</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the actin-binding proteins ADF family. Coactosin subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000124">
        <property type="protein sequence ID" value="OBZ88907.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NIG6"/>
    <dbReference type="STRING" id="101091.A0A1C7NIG6"/>
    <dbReference type="InParanoid" id="A0A1C7NIG6"/>
    <dbReference type="OrthoDB" id="20822at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005884">
        <property type="term" value="C:actin filament"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030864">
        <property type="term" value="C:cortical actin cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030427">
        <property type="term" value="C:site of polarized growth"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051015">
        <property type="term" value="F:actin filament binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030833">
        <property type="term" value="P:regulation of actin filament polymerization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd11282">
        <property type="entry name" value="ADF_coactosin_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.20.10:FF:000018">
        <property type="entry name" value="Coactosin-like 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.20.10">
        <property type="entry name" value="Severin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002108">
        <property type="entry name" value="ADF-H"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029006">
        <property type="entry name" value="ADF-H/Gelsolin-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10829:SF56">
        <property type="entry name" value="ADF-H DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10829">
        <property type="entry name" value="CORTACTIN AND DREBRIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00241">
        <property type="entry name" value="Cofilin_ADF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00102">
        <property type="entry name" value="ADF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55753">
        <property type="entry name" value="Actin depolymerizing proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51263">
        <property type="entry name" value="ADF_H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0009">Actin-binding</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ADF-H" evidence="6">
        <location>
            <begin position="2"/>
            <end position="135"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51263"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OBZ88907.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="149" mass="16733" checksum="E824644629D6A759" modified="2016-11-30" version="1">MSLNVSDPALIDAYEAVRDDKTETNWAFFDFADGKPDRLRVAGTGSGGLSEFVDHLKADVAGWGYVRMNMSNDEYSQRVKFVLVPWCGDSVGIMRKAKLSIQIADVKNVLRNFHIEVPASHKQDLTENEVMTRLRRAGGANYDRQSSNY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NIS3</accession>
    <name>A0A1C7NIS3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">proline--tRNA ligase</fullName>
            <ecNumber evidence="4">6.1.1.15</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">Prolyl-tRNA synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="primary">proS</name>
        <name evidence="14" type="ORF">A0J61_03054</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>tRNA(Pro) + L-proline + ATP = L-prolyl-tRNA(Pro) + AMP + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:14305"/>
            <dbReference type="Rhea" id="RHEA-COMP:9700"/>
            <dbReference type="Rhea" id="RHEA-COMP:9702"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:60039"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78532"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.15"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the class-II aminoacyl-tRNA synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.15" evidence="4"/>
    <dbReference type="EMBL" id="LUGH01000125">
        <property type="protein sequence ID" value="OBZ88900.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NIS3"/>
    <dbReference type="FunCoup" id="A0A1C7NIS3">
        <property type="interactions" value="333"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NIS3"/>
    <dbReference type="InParanoid" id="A0A1C7NIS3"/>
    <dbReference type="OrthoDB" id="10267474at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004827">
        <property type="term" value="F:proline-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006433">
        <property type="term" value="P:prolyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00779">
        <property type="entry name" value="ProRS_core_prok"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.930.10:FF:000066">
        <property type="entry name" value="Proline--tRNA ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.800">
        <property type="entry name" value="Anticodon-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="entry name" value="Bira Bifunctional Protein, Domain 2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002314">
        <property type="entry name" value="aa-tRNA-synt_IIb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006195">
        <property type="entry name" value="aa-tRNA-synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004154">
        <property type="entry name" value="Anticodon-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036621">
        <property type="entry name" value="Anticodon-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002316">
        <property type="entry name" value="Pro-tRNA-ligase_IIa"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004500">
        <property type="entry name" value="Pro-tRNA-synth_IIa_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050062">
        <property type="entry name" value="Pro-tRNA_synthetase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033730">
        <property type="entry name" value="ProRS_core_prok"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00409">
        <property type="entry name" value="proS_fam_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42753">
        <property type="entry name" value="MITOCHONDRIAL RIBOSOME PROTEIN L39/PROLYL-TRNA LIGASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42753:SF2">
        <property type="entry name" value="PROLINE--TRNA LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03129">
        <property type="entry name" value="HGTP_anticodon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00587">
        <property type="entry name" value="tRNA-synt_2b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01046">
        <property type="entry name" value="TRNASYNTHPRO"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52954">
        <property type="entry name" value="Class II aaRS ABD-related"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="Class II aaRS and biotin synthetases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50862">
        <property type="entry name" value="AA_TRNA_LIGASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 14" id="KW-0436">Ligase</keyword>
    <keyword evidence="7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aminoacyl-transfer RNA synthetases class-II family profile" evidence="13">
        <location>
            <begin position="55"/>
            <end position="454"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012831"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00029731"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00047671"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="OBZ88900.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="523" mass="58507" checksum="8A64D3804CE4BCB7" modified="2016-11-30" version="1">MWKAYSSLVFKRHFSVKARHRLSTKFIPVTKEKSSPDSSHATLLKAGFVRQSGAGIYSLLPLGLRTIEKIERIIDEEMQAIGSEKLSLPLLLSPEGWKKTGRWDGAKGEFFRLKDRKESDMLLAPTHEEEITQLVAHDLRSFKQLPIRLYQIGRKYRDELRPRAGLLRGREFIMKDLYSFDASQQQAFETYDQVALAYQRIFQRLHVPFVVAEADSGNIGGSKSHEYHVISSVGEDTLLTCHSCGYTANQELAVGQAVYPSKKDPKTTLVSFSVPDLTETSSYKGTAAILTPPDREPNLLRVQSILTDYLKQHQQMSPRGTMEITPIQQASGELQHVFVDDTLEAAPCSEHAVHHKDHHIRLAQAGDGCRACQEGSLSSVKAIECGHTFYLGTTYSAVLGCQFKDQHQQMVTAEMGCYGIGISRLLAAIAEARYDTQGIAWPESVAPYRVCIVPTDDRREEFKEVAHQIYDALSEVYPDDVVLDDRRSGFGAKMKDSELVGYPYTIIVGPNALKDEAQSEDCG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NJ89</accession>
    <name>A0A1C7NJ89_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Vacuolar amino acid transporter 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">AVT3_0</name>
        <name evidence="9" type="ORF">A0J61_02869</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the amino acid/polyamine transporter 2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000114">
        <property type="protein sequence ID" value="OBZ89090.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NJ89"/>
    <dbReference type="STRING" id="101091.A0A1C7NJ89"/>
    <dbReference type="InParanoid" id="A0A1C7NJ89"/>
    <dbReference type="OrthoDB" id="1684102at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005774">
        <property type="term" value="C:vacuolar membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015179">
        <property type="term" value="F:L-amino acid transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1740.10">
        <property type="entry name" value="Amino acid/polyamine transporter I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013057">
        <property type="entry name" value="AA_transpt_TM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22950">
        <property type="entry name" value="AMINO ACID TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22950:SF666">
        <property type="entry name" value="VACUOLAR AMINO ACID TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01490">
        <property type="entry name" value="Aa_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="20"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="185"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="208"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="256"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="299"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="325"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="363"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="397"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="443"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="491"/>
            <end position="508"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="514"/>
            <end position="535"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="547"/>
            <end position="572"/>
        </location>
    </feature>
    <feature type="domain" description="Amino acid transporter transmembrane" evidence="8">
        <location>
            <begin position="179"/>
            <end position="568"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="70"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="125"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="70"/>
            <end position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008066"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OBZ89090.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="589" mass="64812" checksum="F7F5240A520E40C6" modified="2016-11-30" version="1">MKKDVSLITNQNESKTNYQILGFEEAGWVILVTLILSCTYKRKMEKTPANIRFDEPPSMMIRSQSFDVSRESNPTQLNAHHTNKSHNEGINKRHSTYDNNPRKSFARSVSSISLYSHFAGENFTHHRSNKTSRAPSFEAGKRELDGGDISNHKTMTKSLKSEYDISSVNSDEEGADAPKASVGKAMFMFLKAFIGSGVLFLPKAFDHAGLLLSIAIMVVIAIICLFAYLQLVKTQMLVGGSYGDLGQTLYGKATRYTILSFIALSQMGFVCSYFVFIAGNLVNIVDVLSHCAVQIDQKYYIWFPLIVVAPLVLIRHIAKLSFTAIIADLFILFGLVCCIYFSSQQLKTFGVGPDVKMANPSHFILTVGTAVFSFEGIGLAFGKVIPIVESMERPERFPFVVCVGVSVVCVIYIIIGAVAYLAYGSHIQAAVVYNFPQDHGLTISVQLLYSIAIVLTAPLQLFPATKILEGALFQKCLSGSESNRIKWIKNVFRLCLLAFCALIAFVVGGDNLDIFVSLVGSLACVPLCFIFPGMLHYRVANNRLEKIGDLGLCVFGVVILILTLYVTISSFISPEASGFVLPPYCPIRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NJB4</accession>
    <name>A0A1C7NJB4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">RGS domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">A0J61_02795</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000110">
        <property type="protein sequence ID" value="OBZ89165.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NJB4"/>
    <dbReference type="STRING" id="101091.A0A1C7NJB4"/>
    <dbReference type="InParanoid" id="A0A1C7NJB4"/>
    <dbReference type="OrthoDB" id="3232309at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.167.10">
        <property type="entry name" value="Regulator of G-protein Signalling 4, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016137">
        <property type="entry name" value="RGS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036305">
        <property type="entry name" value="RGS_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044926">
        <property type="entry name" value="RGS_subdomain_2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39466">
        <property type="entry name" value="RGS DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39466:SF1">
        <property type="entry name" value="RGS DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00615">
        <property type="entry name" value="RGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48097">
        <property type="entry name" value="Regulator of G-protein signaling, RGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="210"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="243"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="319"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="domain" description="RGS" evidence="3">
        <location>
            <begin position="125"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="80"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="80"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="101"/>
            <end position="114"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00615"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OBZ89165.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="350" mass="41255" checksum="FB3D651F75D17775" modified="2016-11-30" version="1">MTEYFSTFKDSFQRWFAGSKSDLKDVHIDHILNGTTCQPISLQDFRYYLLNKEYSGENLDFYFWYLDYSARFNCLSEEEKAKSPAPKERPTPTSYNLPLNELKKKTPPQKKEGFDNLPGVPRELEYETEEDQPFRDEVNAVLRTFFHIDSYKELNIEGWMSKHAIYYGCQTTHPEVFADVHEHIYNIMKTSSFKTFLHFALQNMRYSWIILHYVGGVFNLLHLPMILLYTFSNHTSRWYRLSLFPFTFLFSMSILSGRAGFCTIRNMFKIRQVPMYEIDQYYVIQGKMEAFDMKANVDGQKDLTKVIDPDVLKYGRQMFFHIWSISILLALIVTVVGVTLTNEDEPLPTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NJE1</accession>
    <name>A0A1C7NJE1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Succinate dehydrogenase assembly factor 1, mitochondrial</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">A0J61_02855</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion matrix</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the complex I LYR family. SDHAF1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000114">
        <property type="protein sequence ID" value="OBZ89098.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NJE1"/>
    <dbReference type="FunCoup" id="A0A1C7NJE1">
        <property type="interactions" value="185"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NJE1"/>
    <dbReference type="InParanoid" id="A0A1C7NJE1"/>
    <dbReference type="OrthoDB" id="273010at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034553">
        <property type="term" value="P:mitochondrial respiratory chain complex II assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd20268">
        <property type="entry name" value="Complex1_LYR_SDHAF1_LYRM8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008011">
        <property type="entry name" value="Complex1_LYR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045295">
        <property type="entry name" value="Complex1_LYR_SDHAF1_LYRM8"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13675">
        <property type="entry name" value="LYR MOTIF-CONTAINING PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13675:SF1">
        <property type="entry name" value="SUCCINATE DEHYDROGENASE ASSEMBLY FACTOR 1, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05347">
        <property type="entry name" value="Complex1_LYR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0143">Chaperone</keyword>
    <keyword evidence="2" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Complex 1 LYR protein" evidence="5">
        <location>
            <begin position="13"/>
            <end position="69"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004305"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00025715"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF05347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OBZ89098.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="81" mass="9810" checksum="E9E6499B1BF66E60" modified="2016-11-30" version="1">MPAPFKRSGLQNEVISFYRQCFRAAREKPTETRPRFHAFIRREFKEHSIRKTDFATIEYMLRKGKKQFETYSQKGVKDIHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NJQ1</accession>
    <name>A0A1C7NJQ1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Cytochrome b5 domain-containing protein RLF</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">RLF</name>
        <name evidence="7" type="ORF">A0J61_02564</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the cytochrome b5 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000098">
        <property type="protein sequence ID" value="OBZ89392.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NJQ1"/>
    <dbReference type="FunCoup" id="A0A1C7NJQ1">
        <property type="interactions" value="45"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NJQ1"/>
    <dbReference type="InParanoid" id="A0A1C7NJQ1"/>
    <dbReference type="OrthoDB" id="432299at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004128">
        <property type="term" value="F:cytochrome-b5 reductase activity, acting on NAD(P)H"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.120.10:FF:000001">
        <property type="entry name" value="Cytochrome b5 reductase 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.120.10">
        <property type="entry name" value="Cytochrome b5-like heme/steroid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001199">
        <property type="entry name" value="Cyt_B5-like_heme/steroid-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036400">
        <property type="entry name" value="Cyt_B5-like_heme/steroid_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018506">
        <property type="entry name" value="Cyt_B5_heme-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051872">
        <property type="entry name" value="Cytochrome_b5/Flavoprotein_Rdt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46237:SF1">
        <property type="entry name" value="CYTOCHROME B5 REDUCTASE 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46237">
        <property type="entry name" value="CYTOCHROME B5 REDUCTASE 4 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00173">
        <property type="entry name" value="Cyt-b5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01117">
        <property type="entry name" value="Cyt-b5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55856">
        <property type="entry name" value="Cytochrome b5-like heme/steroid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00191">
        <property type="entry name" value="CYTOCHROME_B5_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50255">
        <property type="entry name" value="CYTOCHROME_B5_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 4" id="KW-0349">Heme</keyword>
    <keyword evidence="3 4" id="KW-0408">Iron</keyword>
    <keyword evidence="2 4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cytochrome b5 heme-binding" evidence="6">
        <location>
            <begin position="73"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU362121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OBZ89392.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="152" mass="17297" checksum="771E2DC586F323E8" modified="2016-11-30" version="1">MNSNTPQMNLVDPENQTLDVPEFPSRNGPQRLVAAATKQPRNREKVRLEPGHSPLDWAKLCNSGQDLRGVPCLGRYTLDEVRQHRTQEDAWTAIQGKVYNITPYLKFHPGGVKDLMRCAGKDGTKLFMMTHSWVNMDYLMEKCMVGFLVPSH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NJX9</accession>
    <name>A0A1C7NJX9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">GATA zinc finger domain-containing protein 10</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">gtaJ_0</name>
        <name evidence="7" type="ORF">A0J61_02518</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000096">
        <property type="protein sequence ID" value="OBZ89427.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NJX9"/>
    <dbReference type="STRING" id="101091.A0A1C7NJX9"/>
    <dbReference type="InParanoid" id="A0A1C7NJX9"/>
    <dbReference type="OrthoDB" id="2162994at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00202">
        <property type="entry name" value="ZnF_GATA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.50.10">
        <property type="entry name" value="Erythroid Transcription Factor GATA-1, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051140">
        <property type="entry name" value="GATA_TF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000679">
        <property type="entry name" value="Znf_GATA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013088">
        <property type="entry name" value="Znf_NHR/GATA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45658">
        <property type="entry name" value="GATA TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45658:SF122">
        <property type="entry name" value="GATA ZINC FINGER DOMAIN-CONTAINING PROTEIN 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00320">
        <property type="entry name" value="GATA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00401">
        <property type="entry name" value="ZnF_GATA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57716">
        <property type="entry name" value="Glucocorticoid receptor-like (DNA-binding domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00344">
        <property type="entry name" value="GATA_ZN_FINGER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50114">
        <property type="entry name" value="GATA_ZN_FINGER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="GATA-type" evidence="6">
        <location>
            <begin position="252"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="203"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="203"/>
            <end position="221"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00094"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50114"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OBZ89427.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="302" mass="34504" checksum="79C0319D93CF0B5C" modified="2016-11-30" version="1">MDPKMSFNKKCIENQKKPSLPPISSIDAFYMGESWNSVNSPTSPSIESLNHITMRMQENSIKSTMNDNRYHSRGSLDTLYAHHYHNQVSHSPLTERHVHQDTSFVDNTASRNYNGTLQLHQTEPKPVGISSSSKNLLSLEEDISKVILHCNRLSSSIETQRRQLTQENGNLTRPWLDDMIGKANEVLNALLRLRKIQLATEQRYHHQTDTERKETKPHDMSAKTPSTSGILSFSSGKYRRRGVYKRPVFQGRCHSCNISETPEWRRGPDGARTLCNACGLHYAKLSRKKNLQNNIKTTNSED</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NK83</accession>
    <name>A0A1C7NK83_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative arrestin-related trafficking adapter C2D10.04</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_02734</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000107">
        <property type="protein sequence ID" value="OBZ89209.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NK83"/>
    <dbReference type="STRING" id="101091.A0A1C7NK83"/>
    <dbReference type="InParanoid" id="A0A1C7NK83"/>
    <dbReference type="OrthoDB" id="2238745at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030674">
        <property type="term" value="F:protein-macromolecule adaptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031625">
        <property type="term" value="F:ubiquitin protein ligase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070086">
        <property type="term" value="P:ubiquitin-dependent endocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.640">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014752">
        <property type="entry name" value="Arrestin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011021">
        <property type="entry name" value="Arrestin-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050357">
        <property type="entry name" value="Arrestin_domain-protein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11188">
        <property type="entry name" value="ARRESTIN DOMAIN CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11188:SF17">
        <property type="entry name" value="FI21816P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00339">
        <property type="entry name" value="Arrestin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="E set domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Arrestin-like N-terminal" evidence="2">
        <location>
            <begin position="34"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="329"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="329"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="362"/>
            <end position="384"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ89209.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="511" mass="57618" checksum="57CA8A85FF41A93E" modified="2016-11-30" version="1">MQLGLLSHGHLAFDPLKPVILRGLPTEDASTLFAGHVVLTLSKPTKISNVSVRFKSQMVTYWPEGTRGTKLTAEKLLGEQTVELLSPEKRKDLILTAGTHRFSFAFVIPNSTVATIEDTFGRVRHNVEAEVQRPGMMLLSNWRISKPVMVLRTYMSNSLLTNNSLANLSKTFEKHTVYGDIEVLIEAAAFSSGELFYIRLIIEPQLKHTRLEHMEVSVTETRRYCVPEFRAWRNDQVMFQMPFAGSVRLAEFGEVDVTTDQLMPIFDKQQNGIELIHDFAHRLAFFAPTCEQNIHHTTYIKEIQFRHRLEINLTLSYLDNEGHRQFISRSNSDSIGSTQVPEPFVLMPPPAAHFSNTRTTGSLSAPNTSPSSSAPPSRPGSPVSTPTSWSDMLLRLNKTKTEKLEGRNRETITLDTPITVFDCRLKEDYGKLPSYFELGVQPTVSSINKKATKPKFTATMDKPNQPHPYLCACYHAFCREMELASESLYLSSPAMPLMDRIPSIPPPDYQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NKR0</accession>
    <name>A0A1C7NKR0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Siderophore iron transporter mirB</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">mirB</name>
        <name evidence="8" type="ORF">A0J61_02222</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000081">
        <property type="protein sequence ID" value="OBZ89717.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NKR0"/>
    <dbReference type="FunCoup" id="A0A1C7NKR0">
        <property type="interactions" value="9"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NKR0"/>
    <dbReference type="InParanoid" id="A0A1C7NKR0"/>
    <dbReference type="OrthoDB" id="4078873at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000284">
        <property type="entry name" value="Siderophore iron transporter mirB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23501:SF3">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="79"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="118"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="147"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="175"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="202"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="232"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="289"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="316"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="358"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="395"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="425"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="450"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="564"/>
            <end position="583"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="36"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OBZ89717.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="599" mass="66545" checksum="A8290E87994B737D" modified="2016-11-30" version="1">MKFRLPSLLPAPAPDAKDELDTQNGMVDAATTKSKLSLEDGLENHSESDKSSGVDTSEFQYGVQSVQAVNQVWTKGQLILAYVLIWIISFVLAFSSGINSTLTPYVTSSFQEHSLTATTQIMSGLISGLIVLPYAKLLNVWGRPQCFGLMVCSITLGLIMMAACQNVETYCAAQVFYSVGSSTLNFTMTIFIADTTSLRNRAFMIAFSASPWLVTVWAFGPAAQSILNTIGFRWGFGIWAIVIPIVCAPLYGLFYYNLLKARKAGLVPKVEHNRTWRESFVYYMREFDIIGLLLIVAGLALFLLSFNLYAKQPLQWKSPLIICFLVIGGLLIIAFGFWEKYGSSKTFIPWNLMMDRTVFSTYTMVVSIYLSWYLWDSFFYSYLIVVYNITISQATYITNIYTIGSTFWAIVMGILIRYNGRLKWISLYFGAPATILGVGLMIHFRQPDVNIGFIVMCQIFIALGGGTLVICEQMTVMAVASHQYVPAVLAMENMIASVAGSIGSTIAGAMWTGLFPQKLAQNLPESALGNLEAIYGSIEVQTSYPVGSLERDGINRAYSDTQRLMLIAATCIYSITLVSIMFWKDIDVKHLKKVKGLVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NKY3</accession>
    <name>A0A1C7NKY3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">A0J61_02291</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5 6">Belongs to the peptidase S8 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000084">
        <property type="protein sequence ID" value="OBZ89658.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NKY3"/>
    <dbReference type="FunCoup" id="A0A1C7NKY3">
        <property type="interactions" value="24"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NKY3"/>
    <dbReference type="InParanoid" id="A0A1C7NKY3"/>
    <dbReference type="OrthoDB" id="206201at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04077">
        <property type="entry name" value="Peptidases_S8_PCSK9_ProteinaseK_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.200:FF:000007">
        <property type="entry name" value="Subtilisin-like serine protease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.80">
        <property type="entry name" value="Peptidase S8 propeptide/proteinase inhibitor I9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.200">
        <property type="entry name" value="Peptidase S8/S53 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034193">
        <property type="entry name" value="PCSK9_ProteinaseK-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000209">
        <property type="entry name" value="Peptidase_S8/S53_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036852">
        <property type="entry name" value="Peptidase_S8/S53_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023827">
        <property type="entry name" value="Peptidase_S8_Asp-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022398">
        <property type="entry name" value="Peptidase_S8_His-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023828">
        <property type="entry name" value="Peptidase_S8_Ser-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050131">
        <property type="entry name" value="Peptidase_S8_subtilisin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015500">
        <property type="entry name" value="Peptidase_S8_subtilisin-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010259">
        <property type="entry name" value="S8pro/Inhibitor_I9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037045">
        <property type="entry name" value="S8pro/Inhibitor_I9_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43806:SF11">
        <property type="entry name" value="CEREVISIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43806">
        <property type="entry name" value="PEPTIDASE S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05922">
        <property type="entry name" value="Inhibitor_I9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00082">
        <property type="entry name" value="Peptidase_S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00723">
        <property type="entry name" value="SUBTILISIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52743">
        <property type="entry name" value="Subtilisin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51892">
        <property type="entry name" value="SUBTILASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00136">
        <property type="entry name" value="SUBTILASE_ASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00137">
        <property type="entry name" value="SUBTILASE_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00138">
        <property type="entry name" value="SUBTILASE_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 5 6" id="KW-0645">Protease</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5 6" id="KW-0720">Serine protease</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008889761" evidence="7">
        <location>
            <begin position="19"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="domain" description="Inhibitor I9" evidence="9">
        <location>
            <begin position="45"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S8/S53" evidence="8">
        <location>
            <begin position="168"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="5">
        <location>
            <position position="177"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="5">
        <location>
            <position position="209"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="5">
        <location>
            <position position="374"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003355"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF05922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OBZ89658.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="456" mass="48877" checksum="C155901F4F92F292" modified="2016-11-30" version="1">MKLSIVASAVLAASFVNAKPLSYQDPKNTMAPLYVSPETETIANSYIVVLKDSLQSHEIREHAAWINTLTESSTKNIHLSDYLDPHTTVAGIKHVYDTPNLKGYAGKFDDQVLEAIRQSDDVAFIEHDSVVYANELQRSAPWGLSRISHRDTLTFKNYQQYEYNPDGGEGVKVYVIDTGINVDHNDFDGRATWGHTVPSNDVDEDGNGHGSHCAGTIAGKRYGVAKKAQPVAVKVLRSSGSGTMSDVVRGVDWATSEHLKEAAAAKKNNTKYKGAVANMSLGGGKSPSLDLAVNGAVDSGVVFAVAAGNDNRDACNYSPAAAEKAITVGASTISDERAYFSNYGECVDVFAPGLNILSIWKGSRWATNTISGTSMASPHVAGLAAYLLSLEEGEVTPKQIKDKILKLATKNVLEKLPEGTPNLLIYNGIAEKSLKDTFSDAVGSVDGVLKEFFGDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NKZ8</accession>
    <name>A0A1C7NKZ8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">GPN-loop GTPase 2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">Gpn2</name>
        <name evidence="6" type="ORF">A0J61_02785</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Small GTPase required for proper localization of RNA polymerase II and III (RNAPII and RNAPIII). May act at an RNAP assembly step prior to nuclear import.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Binds to RNA polymerase II (RNAPII).</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the GPN-loop GTPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000110">
        <property type="protein sequence ID" value="OBZ89156.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NKZ8"/>
    <dbReference type="FunCoup" id="A0A1C7NKZ8">
        <property type="interactions" value="767"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NKZ8"/>
    <dbReference type="InParanoid" id="A0A1C7NKZ8"/>
    <dbReference type="OrthoDB" id="5839at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034087">
        <property type="term" value="P:establishment of mitotic sister chromatid cohesion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006606">
        <property type="term" value="P:protein import into nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd17871">
        <property type="entry name" value="GPN2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000338">
        <property type="entry name" value="GPN-loop GTPase 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004130">
        <property type="entry name" value="Gpn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030231">
        <property type="entry name" value="Gpn2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21231:SF3">
        <property type="entry name" value="GPN-LOOP GTPASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21231">
        <property type="entry name" value="XPA-BINDING PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03029">
        <property type="entry name" value="ATP_bind_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="3 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU365059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OBZ89156.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="296" mass="33610" checksum="67171B5A3BDC0262" modified="2016-11-30" version="1">MPFGQVIVGPPGSGKTTYCWGAYQYLTAIGRKVAIVNLDPANDNIPYPCAVNIFDLITLEDTMNELGLGPNGGIMFCIEYLLKNMDWLTDQLKQLDDHYILFDFPGQVELFTHHAAVKDLLHALEKIDYRLVAVNMVDAHYCTDPTKYISVLLLALKTMIQLELPHVNVLSKVDLIESYGKLRFNLQYYTEVMDLSYLLDSLNEDPFGSKYKKLNEALCELVQDFSLVGFYTLCVEEKDSMTKLQQVIDKAGGFIFGGLTEGNESIMLTAMKAGYHEDVSDVQERWLHKEEEEDFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NLD3</accession>
    <name>A0A1C7NLD3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Inhibitor I9 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">A0J61_02290</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the protease inhibitor I9 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000084">
        <property type="protein sequence ID" value="OBZ89659.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NLD3"/>
    <dbReference type="InParanoid" id="A0A1C7NLD3"/>
    <dbReference type="OrthoDB" id="5518345at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004866">
        <property type="term" value="F:endopeptidase inhibitor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042144">
        <property type="term" value="P:vacuole fusion, non-autophagic"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.80">
        <property type="entry name" value="Peptidase S8 propeptide/proteinase inhibitor I9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052471">
        <property type="entry name" value="PBI_I9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010259">
        <property type="entry name" value="S8pro/Inhibitor_I9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037045">
        <property type="entry name" value="S8pro/Inhibitor_I9_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28288">
        <property type="entry name" value="PROTEASE B INHIBITOR 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28288:SF2">
        <property type="entry name" value="PROTEASE B INHIBITOR 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05922">
        <property type="entry name" value="Inhibitor_I9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54897">
        <property type="entry name" value="Protease propeptides/inhibitors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008889772" description="Inhibitor I9 domain-containing protein" evidence="2">
        <location>
            <begin position="20"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="domain" description="Inhibitor I9" evidence="3">
        <location>
            <begin position="22"/>
            <end position="89"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00038069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF05922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OBZ89659.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="89" mass="10117" checksum="89B8FEEA42D8D2E8" modified="2016-11-30" version="1">MFRFIYCLIVLLAITQVFAIDYIIALKPPVTEASYEQVRKDVQSMGGKITYEFRASLKAVLASLPSERIDTLSSKPYVDFVEKDKSVHI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-06-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NLE7</accession>
    <name>A0A1C7NLE7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_03830</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000174">
        <property type="protein sequence ID" value="OBZ88114.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NLE7"/>
    <dbReference type="InParanoid" id="A0A1C7NLE7"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ88114.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="71" mass="8444" checksum="A17B7A7FB52C60A8" modified="2016-11-30" version="1">MFYIIFFCNGEQVKHLYALEADFRQISLKHIEGSLLDVACQHPEDLWCSCEYYTFTLTLDSEFPLRIEFVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NMA8</accession>
    <name>A0A1C7NMA8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">phosphoglycerate dehydrogenase</fullName>
            <ecNumber evidence="3">1.1.1.95</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">SER33</name>
        <name evidence="9" type="ORF">A0J61_01687</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>(2R)-3-phosphoglycerate + NAD(+) = 3-phosphooxypyruvate + NADH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:12641"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:18110"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:58272"/>
            <dbReference type="EC" id="1.1.1.95"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Amino-acid biosynthesis; L-serine biosynthesis; L-serine from 3-phospho-D-glycerate: step 1/3.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.95" evidence="3"/>
    <dbReference type="EMBL" id="LUGH01000056">
        <property type="protein sequence ID" value="OBZ90271.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NMA8"/>
    <dbReference type="FunCoup" id="A0A1C7NMA8">
        <property type="interactions" value="321"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NMA8"/>
    <dbReference type="InParanoid" id="A0A1C7NMA8"/>
    <dbReference type="OrthoDB" id="418179at2759"/>
    <dbReference type="UniPathway" id="UPA00135">
        <property type="reaction ID" value="UER00196"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047545">
        <property type="term" value="F:(S)-2-hydroxyglutarate dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004617">
        <property type="term" value="F:phosphoglycerate dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006564">
        <property type="term" value="P:L-serine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd04901">
        <property type="entry name" value="ACT_3PGDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd12176">
        <property type="entry name" value="PGDH_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000041">
        <property type="entry name" value="D-3-phosphoglycerate dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.260">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045865">
        <property type="entry name" value="ACT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002912">
        <property type="entry name" value="ACT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050418">
        <property type="entry name" value="D-iso_2-hydroxyacid_DH_PdxB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006139">
        <property type="entry name" value="D-isomer_2_OHA_DH_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029753">
        <property type="entry name" value="D-isomer_DH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029752">
        <property type="entry name" value="D-isomer_DH_CS1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006140">
        <property type="entry name" value="D-isomer_DH_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF008759">
        <property type="entry name" value="PRK11790.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43761:SF1">
        <property type="entry name" value="D-ISOMER SPECIFIC 2-HYDROXYACID DEHYDROGENASE CATALYTIC DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43761">
        <property type="entry name" value="D-ISOMER SPECIFIC 2-HYDROXYACID DEHYDROGENASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_1G13630)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00389">
        <property type="entry name" value="2-Hacid_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02826">
        <property type="entry name" value="2-Hacid_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55021">
        <property type="entry name" value="ACT-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52283">
        <property type="entry name" value="Formate/glycerate dehydrogenase catalytic domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51671">
        <property type="entry name" value="ACT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00065">
        <property type="entry name" value="D_2_HYDROXYACID_DH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00670">
        <property type="entry name" value="D_2_HYDROXYACID_DH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0520">NAD</keyword>
    <keyword evidence="4 7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ACT" evidence="8">
        <location>
            <begin position="370"/>
            <end position="440"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005216"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005854"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013143"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00048731"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003719"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51671"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OBZ90271.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="440" mass="48361" checksum="01B90289FF0EEB02" modified="2016-11-30" version="1">MSTESTPEPIQNRRRGSSFGFSKPKVLKPFNTAEVKILLLENVNATAIEAFKKQGYQVETHTKALVGEELIEKIRDVHIIGIRSKTKLTKAVLDEAKNLMAIGCFCIGTNQVDLKAAADKGIAVFNSPFSNSRSVAELVIGELITLARQLGDRNTEMHQGVWNKVSKGCYEIRHKVLGIVGYGHIGSQLSVLAEAMGMTVYFYDVLQIMPIGQAKQVESLEDLLSISDFVSLHVPETEETKNMIGEREIMDYMKKGSYLLNNARGTVVQIPALIKGLQSGHLAGAAVDVYPKEPAANGPHFDYYPELLSANNLILTPHIGGSTEEAQSMIGVEVSTALTKFINEGCSLGAVNFPEIDLRAISQDDKDTVRVLYIHRNIPGVLRAINEIFANHNVEKQYSDSKGEIAYVMADISNVTQEHLESLYNAIVATPANIKTRVLY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NMF4</accession>
    <name>A0A1C7NMF4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_01701</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the PPR family. P subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000057">
        <property type="protein sequence ID" value="OBZ90255.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NMF4"/>
    <dbReference type="STRING" id="101091.A0A1C7NMF4"/>
    <dbReference type="InParanoid" id="A0A1C7NMF4"/>
    <dbReference type="OrthoDB" id="185373at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050872">
        <property type="entry name" value="PPR_P_subfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002885">
        <property type="entry name" value="PPR_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46128">
        <property type="entry name" value="MITOCHONDRIAL GROUP I INTRON SPLICING FACTOR CCM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46128:SF285">
        <property type="entry name" value="PENTATRICOPEPTIDE REPEAT-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13041">
        <property type="entry name" value="PPR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007626"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ90255.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="357" mass="41155" checksum="B775AD2507CC7D0F" modified="2016-11-30" version="1">MVHIRCHRLQSKVNQHLLWKSLLESSRTCYIRQTATLASRPRKDLLNEIDQLEHQHALWQLKSSGKKRIPVHVGAKIKKELASPTLLSLHTSLQQNDLENAWKQFDALTSEVLPRSTARLLLGSLHTLVNANLPRLTLDFAKLQKLYTARLELLAGIVRRNKELHWDKDEVAMVIELYGKLDQVKKAETIVRNLAYYSTAPLNIELYNELLAVYVRRFRSVDDTTKRRFLSKMKTIELEMARKGIQPNITSYNLLLAARLKMQDLREAERIFNSMACTPDRNTYHILLNGYLKGSRSSRDIEITNQWMDRLVASGITPNKRTFKSVMDGLSDQAINQIQRQSTPCSNVTQLPMIESK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NMW9</accession>
    <name>A0A1C7NMW9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">RING-type E3 ubiquitin transferase</fullName>
            <ecNumber evidence="4">2.3.2.27</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">A0J61_01503</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.</text>
            <dbReference type="EC" id="2.3.2.27"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="11">Belongs to the ZNF598/HEL2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.27" evidence="4"/>
    <dbReference type="EMBL" id="LUGH01000049">
        <property type="protein sequence ID" value="OBZ90437.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NMW9"/>
    <dbReference type="FunCoup" id="A0A1C7NMW9">
        <property type="interactions" value="83"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NMW9"/>
    <dbReference type="InParanoid" id="A0A1C7NMW9"/>
    <dbReference type="OrthoDB" id="3838338at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043022">
        <property type="term" value="F:ribosome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016567">
        <property type="term" value="P:protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072344">
        <property type="term" value="P:rescue of stalled ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd16615">
        <property type="entry name" value="RING-HC_ZNF598"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057634">
        <property type="entry name" value="PAH_ZNF598/HEL2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041888">
        <property type="entry name" value="RING-HC_ZNF598/HEL2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056437">
        <property type="entry name" value="Znf-C2H2_ZNF598/HEL2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044288">
        <property type="entry name" value="ZNF598/HEL2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22938:SF0">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE ZNF598"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22938">
        <property type="entry name" value="ZINC FINGER PROTEIN 598"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23202">
        <property type="entry name" value="PAH_ZNF598"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25447">
        <property type="entry name" value="RING_ZNF598"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23230">
        <property type="entry name" value="zf-C2H2_13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <keyword evidence="10" id="KW-0862">Zinc</keyword>
    <keyword evidence="9 12" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="14">
        <location>
            <begin position="29"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="298"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="500"/>
            <end position="533"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="546"/>
            <end position="661"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="334"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="13">
        <location>
            <begin position="646"/>
            <end position="655"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00035113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="OBZ90437.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="661" mass="74904" checksum="8545C4166433324D" modified="2016-11-30" version="1">MSNTKKDKQKERKPNRSLPKEEEEEGELCFICTEPVSIFAVSECDHRTCHKCTLRLRALYETRNCAYCKAEQKWVLLTKDADKPFDQYIPSDTPFADKELNIRFETQEMYNEAMNLLKYNCPHDCQETANDLTELKLHVRKTHGLNLCDLCCQHKKVFPSEQYLYTASQLTKHYREGDKDFNKEDETGFSGHPECSFCKTRFYGTDELFVHCRDQHEQCFICVRNGKRHEYYVNYASLEDHFKSDHFICPYPSCLEKKFVVFESSIDLKAHEVEVHGESISGLQRSLQSQSRQLEVNFQYESYRDQRKKGKKREEQTATPPPSNSLDAFPRIDSSSSIASSSNSNNSNQQKEPAKPARTVPGASTKKGKGKAIQKPAGFGALSGTPVDVAPPTNALSSSTTESQHDLNTVALHTDFIGKVGNMLQSKAKVQEFRTLTSAYRKSNISCQDYVNQIYLLTNQHVQNTARIIKGVEDLLDIEDKKTELIRVWRNKQTALSNFPALETKEKPKQPASRVLVIKPQPKKSVVGQKKKTSNNVWDKVATAASVATSSRSPLSSATNSPQTSRPSSPPSTPPSWASDQRSPERQSKNDFPSLKPQLFPSLPTAAPKHDIIRNMRQNKQANGYAWGSSATDLPEQQQEDTQDNKKKKGRKNKVLFRVGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NMY9</accession>
    <name>A0A1C7NMY9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Transcription elongation regulator 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">Tcerg1</name>
        <name evidence="5" type="ORF">A0J61_01449</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000046">
        <property type="protein sequence ID" value="OBZ90501.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NMY9"/>
    <dbReference type="FunCoup" id="A0A1C7NMY9">
        <property type="interactions" value="186"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NMY9"/>
    <dbReference type="InParanoid" id="A0A1C7NMY9"/>
    <dbReference type="OrthoDB" id="410044at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070063">
        <property type="term" value="F:RNA polymerase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003712">
        <property type="term" value="F:transcription coregulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00201">
        <property type="entry name" value="WW"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.70.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.440">
        <property type="entry name" value="FF domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002713">
        <property type="entry name" value="FF_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036517">
        <property type="entry name" value="FF_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045148">
        <property type="entry name" value="TCRG1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001202">
        <property type="entry name" value="WW_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036020">
        <property type="entry name" value="WW_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15377">
        <property type="entry name" value="TRANSCRIPTION ELONGATION REGULATOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15377:SF3">
        <property type="entry name" value="WW DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01846">
        <property type="entry name" value="FF"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00397">
        <property type="entry name" value="WW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00441">
        <property type="entry name" value="FF"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00456">
        <property type="entry name" value="WW"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81698">
        <property type="entry name" value="FF domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51045">
        <property type="entry name" value="WW domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51676">
        <property type="entry name" value="FF"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01159">
        <property type="entry name" value="WW_DOMAIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50020">
        <property type="entry name" value="WW_DOMAIN_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="WW" evidence="3">
        <location>
            <begin position="16"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="domain" description="WW" evidence="3">
        <location>
            <begin position="71"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="domain" description="FF" evidence="4">
        <location>
            <begin position="272"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="domain" description="FF" evidence="4">
        <location>
            <begin position="329"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="102"/>
            <end position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OBZ90501.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="387" mass="46536" checksum="1398530BFA93FD4F" modified="2016-11-30" version="1">MDLTTQPPAYYTPGVPTLPPGWVEYRTPTGQPYWYNTATHLSSWVFPFHPNLTLNQPKKKQIKKKIPNTHWLFVLTPDGYEFYYDRDTKTSVWEMPPELKEPMEELKQLEQAEEEERKKREEEEKERETKRIKLEEEQQAATEMTEDDIMWQLQQMGEQDEDDMVYIEPEQEPLQQTEEEVVVKETEEIKKTTLSEEECIAQFNQLLEERNISPFAVYSVEYPQLMTDPRFSCKLKISYSCLKMVSQQKQKALFNKYCNALGERLKHQNKSKKKPEEEFRELLESKVTEKMYWDDFRRKYKNDPRFKAISATREKEAMFKDYVRHELGKPKTGKEAYMDLLRSTKEIKVGIRWRDAKKILEKDDRFYAIESKTEREDVFRDYLDEIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NP57</accession>
    <name>A0A1C7NP57_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative methyltransferase C1B3.06c</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_01190</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000034">
        <property type="protein sequence ID" value="OBZ90760.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NP57"/>
    <dbReference type="STRING" id="101091.A0A1C7NP57"/>
    <dbReference type="InParanoid" id="A0A1C7NP57"/>
    <dbReference type="OrthoDB" id="2013972at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041698">
        <property type="entry name" value="Methyltransf_25"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43591:SF24">
        <property type="entry name" value="2-METHOXY-6-POLYPRENYL-1,4-BENZOQUINOL METHYLASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43591">
        <property type="entry name" value="METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13649">
        <property type="entry name" value="Methyltransf_25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransferase" evidence="2">
        <location>
            <begin position="243"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="119"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="422"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="28"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="122"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="153"/>
            <end position="165"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ90760.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="510" mass="57202" checksum="0FA0D76DAE97BF8A" modified="2016-11-30" version="1">MRPMYTADMLTESNWHNRKQHTKTYNMNSTPSLSPSASSTSSNASSAGVADSECPVHHAYSTCGDTSATAPLPPTRPKRPLSAEVLIKIMDKRLFKKKQRELQRAQEEQWMHYQTLRTPNLSSAASSSSSSSSPQTSSRLNGLIHLKPSSSSHSRKQSLKKKLRSTPKDQPTKNNITTVKKMASHTPMLSTNTNSNHDVFPYVLTQDNDEQDRMVTQHYILRTAFGADYMSPIRTRLEQGIIVLDVGCGPGTWTMEMGTTFPNSTFIGIDQAAFFPKDIKPRNCHFRTCGPLLVGQQGKEDLTLPFPDNSIDYIYQRDMNWGLTAQTWQPLLLEYQRILKPGGWIECVEPDLSTQNSLGNECAMNDKLISGLAMRQQDPYAVHRLPTVLAINGFRQVEDISQTLPLGWGSFYDATNKSTSTLSSTKTAKRSSQSSHADAESSSNQECSTFAKAVSSQYLYMLKSLKPWLSDMMHMSSQKYDAYIASLPEEWVRARTFVKWHSIIAQKPFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NP63</accession>
    <name>A0A1C7NP63_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein C16C9.01c</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_01261</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000038">
        <property type="protein sequence ID" value="OBZ90669.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NP63"/>
    <dbReference type="FunCoup" id="A0A1C7NP63">
        <property type="interactions" value="2"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NP63"/>
    <dbReference type="InParanoid" id="A0A1C7NP63"/>
    <dbReference type="OrthoDB" id="497927at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1190.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011611">
        <property type="entry name" value="PfkB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029056">
        <property type="entry name" value="Ribokinase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47098">
        <property type="entry name" value="PROTEIN MAK32"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47098:SF2">
        <property type="entry name" value="PROTEIN MAK32"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00294">
        <property type="entry name" value="PfkB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53613">
        <property type="entry name" value="Ribokinase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Carbohydrate kinase PfkB" evidence="1">
        <location>
            <begin position="42"/>
            <end position="306"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ90669.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="332" mass="37775" checksum="BD3139B49550C5E9" modified="2016-11-30" version="1">MAPLFSSIGGLIIDDIVYQDGKRVQDVLGGGGVFAVYGMRLWHLDSESKHVGYIVHKGFDYPSQIDQELNQLDISILSIHHPDKHTTRGLNTFRENDHRDFEYIHPIIRVTADDFPDSWIQSLKILHLICSAERAIEIVDQWRAREQQLEAAYPTQFIWEPLPWACLPENLDCIIEAAKQIDIISPNHEELANMLGFDFHELLAQKRHDVKHTTEHLAQEFISKVSCTLVVRVGKYGALVMQETPSWVPAYWNWKEESQHVVDVTGAGNTFCGGFAYGWIQTKGDAHASAYYGAVAASYAVEQVGVPDITQWKVKDKPEFRLNRLKNQSCVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-06-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NPA1</accession>
    <name>A0A1C7NPA1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_00989</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000026">
        <property type="protein sequence ID" value="OBZ90963.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NPA1"/>
    <dbReference type="InParanoid" id="A0A1C7NPA1"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ90963.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="99" mass="11614" checksum="BB98B99F4989F9E1" modified="2016-11-30" version="1">MSAQEDIDILLPLQLQQQKDSHHHDLINTAQNKLLMLLTYWIITKRQAKDKQESRICERVFIYGSVDIIAGHKDIKLKISDFSFSNDYIKIVNQGLRFQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NPQ4</accession>
    <name>A0A1C7NPQ4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Protein kinase kin1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">kin1_5</name>
        <name evidence="10" type="ORF">A0J61_01073</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. NIM1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000030">
        <property type="protein sequence ID" value="OBZ90889.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NPQ4"/>
    <dbReference type="STRING" id="101091.A0A1C7NPQ4"/>
    <dbReference type="InParanoid" id="A0A1C7NPQ4"/>
    <dbReference type="OrthoDB" id="193931at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035556">
        <property type="term" value="P:intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000226">
        <property type="term" value="P:microtubule cytoskeleton organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000571">
        <property type="entry name" value="Maternal embryonic leucine zipper kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24346:SF82">
        <property type="entry name" value="KP78A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24346">
        <property type="entry name" value="MAP/MICROTUBULE AFFINITY-REGULATING KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 10" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="9">
        <location>
            <begin position="39"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="430"/>
            <end position="516"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="532"/>
            <end position="699"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="17"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="442"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="484"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="496"/>
            <end position="516"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="549"/>
            <end position="568"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="580"/>
            <end position="601"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="602"/>
            <end position="616"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="624"/>
            <end position="640"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="70"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010791"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OBZ90889.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="823" mass="93425" checksum="5A2025A83DF17A00" modified="2016-11-30" version="1">MQATTDQKAKRQPSTKQSRESLSRKTSERHQVMKIQNYVIYRKTIGAGSMGKVKLAECLTDPDKQKYAVKIMPKVDFEALAGKTKSKDPKDTPEEREQRTIREMAIMRLLRHPNICQLKEYITEGDKYYMFLEYVDGGQLLDYIIKHGKLREKQARRFARQIVSALDYCHRNSIVHRDLKIENILITQSEQLKIIDFGLSNVYSPTQQLDTFCGSLYFAAPELLRAKHYTGPEVDIWSFGVVLYVLVCGRVPFDDTNLPALHEKIKAGVVEDYPDHLGKDCLDLLSKIFVVDPAQRITLSAIQAHPWMNKGYEEPIRNYLPRRQPIEHIDMDIVKGMHGFGLGSPEEIREKLEKIIHSPDYQSAASKIDQNFQKKVNDDQSLANKSRWRRSLSTRKKTVIQDDFQTLPAMYDPLVSVYYLVKERKESDERKQQLLNAEPNALTLSRSTSTLVGSQSSRPDSTQEPAVPLARSKSTGTRRRTSKKLPDLPSLKKETATQTAPNTPVPSKSERVSTSTLIRKKSIQAVKKFGLKIPGIGNPSVQAPDDGASDTSVVPASRTSSKRSNASVPASADPRERSTESIPTSASSRKSTWLKQSSNDATLRDQQKRQTQELSRRPSWRKLSFSQKSTPPSLDQSTLDDAQEAKTAVSVSPSQSSKSKHEEGIVDQKNLPPVTLKKSTSERVPSSKNRAKSPSPPKSFFNFNRGHLFRVTSMQIMIDLQQVLDQLHIPFSNSTADQFTFHCVCPHSVWKHYVTLSPEETQNIPDYGDLKFSVMVYEARWAGHKMGIKVKEHDEHNTHNFYTKQILRNINHALLGQFEKMYN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NQ61</accession>
    <name>A0A1C7NQ61_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Neurochondrin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">Ncdn</name>
        <name evidence="1" type="ORF">A0J61_00918</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000024">
        <property type="protein sequence ID" value="OBZ91049.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NQ61"/>
    <dbReference type="STRING" id="101091.A0A1C7NQ61"/>
    <dbReference type="InParanoid" id="A0A1C7NQ61"/>
    <dbReference type="OrthoDB" id="8962942at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008709">
        <property type="entry name" value="Neurochondrin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13109">
        <property type="entry name" value="NEUROCHONDRIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13109:SF7">
        <property type="entry name" value="NEUROCHONDRIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05536">
        <property type="entry name" value="Neurochondrin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ91049.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="298" mass="33764" checksum="463D76AF6D38F4B2" modified="2016-11-30" version="1">MELCNSIVQFLTHEFKLTMNITSNARDRSAEIDRCLSMIVPSASDESKFVGMLILPKLLDQNKPEDIERVFKGMNFKFIERLLRNNQTMDAQVPDPVLKEIAVNILSCFAHYETLASEPAMADRIPALSRLLVPNQSLTREILMILLHVAVKKEGLVRMLDPDVLKNVSEVLFQTDQSEERTACTELMVSVYQRACGLVSQEKIPSLASALKYSFSTLLSILSNALDQDQKLLKFEALHILSHVLPAASLEMMQQVKKEQSEQKIEGWLDHLLNGIRQLLTSKLRNVIIQSEKQQQTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NQ96</accession>
    <name>A0A1C7NQ96_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">NDUFAF3</name>
        <name evidence="1" type="ORF">A0J61_00765</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000019">
        <property type="protein sequence ID" value="OBZ91198.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NQ96"/>
    <dbReference type="STRING" id="101091.A0A1C7NQ96"/>
    <dbReference type="InParanoid" id="A0A1C7NQ96"/>
    <dbReference type="OrthoDB" id="20681at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032981">
        <property type="term" value="P:mitochondrial respiratory chain complex I assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1230.10">
        <property type="entry name" value="MTH938-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036748">
        <property type="entry name" value="MTH938-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007523">
        <property type="entry name" value="NDUFAF3/AAMDC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21192:SF2">
        <property type="entry name" value="NADH DEHYDROGENASE [UBIQUINONE] 1 ALPHA SUBCOMPLEX ASSEMBLY FACTOR 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21192">
        <property type="entry name" value="NUCLEAR PROTEIN E3-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04430">
        <property type="entry name" value="DUF498"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64076">
        <property type="entry name" value="MTH938-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0830">Ubiquinone</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ91198.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="203" mass="23120" checksum="FDAF9D7BBF046CF3" modified="2016-11-30" version="1">MLRLLTRRTLATHNQKQAYRAFSQTVYKRSNKTEEDAWEQAKVDPSKIANQVVPQPANDAVPNSMLSAFTNMFDRGPNVGIDVILKHGFVLTNKVRVEHPIILLNGSPFLWKAPRRAEGFMPMKDWELEAFKMFEIVSPKPELIIFGTGREFAPIPEHIRQFFFKLGVQVDQMSTKHASATYNVLAEEGRRVAAALLPLDEKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NQC9</accession>
    <name>A0A1C7NQC9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">General negative regulator of transcription subunit 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="primary">cnot1_1</name>
        <name evidence="15" type="ORF">A0J61_00642</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Acts as a component of the CCR4-NOT core complex, which in the nucleus seems to be a general transcription factor, and in the cytoplasm the major mRNA deadenylase involved in mRNA turnover. The NOT protein subcomplex negatively regulates the basal and activated transcription of many genes. Preferentially affects TC-type TATA element-dependent transcription. Could directly or indirectly inhibit component(s) of the general transcription machinery.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000015">
        <property type="protein sequence ID" value="OBZ91327.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="FunCoup" id="A0A1C7NQC9">
        <property type="interactions" value="770"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NQC9"/>
    <dbReference type="InParanoid" id="A0A1C7NQC9"/>
    <dbReference type="OrthoDB" id="1933107at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030015">
        <property type="term" value="C:CCR4-NOT core complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000932">
        <property type="term" value="C:P-body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0060090">
        <property type="term" value="F:molecular adaptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017148">
        <property type="term" value="P:negative regulation of translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000289">
        <property type="term" value="P:nuclear-transcribed mRNA poly(A) tail shortening"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd20710">
        <property type="entry name" value="NOT1_connector"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.180:FF:000012">
        <property type="entry name" value="Ccr4-Not transcription complex subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.800:FF:000001">
        <property type="entry name" value="CCR4-NOT transcription complex subunit 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.790">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.800">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.840">
        <property type="entry name" value="CCR4-NOT transcription complex subunit 1 TTP binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007196">
        <property type="entry name" value="CCR4-Not_Not1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055454">
        <property type="entry name" value="CNOT1-like_NOT1_connector"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032191">
        <property type="entry name" value="CNOT1_CAF1_bind"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024557">
        <property type="entry name" value="CNOT1_dom_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032194">
        <property type="entry name" value="CNOT1_HEAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032193">
        <property type="entry name" value="CNOT1_TTP_bind"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038535">
        <property type="entry name" value="CNOT1_TTP_bind_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040398">
        <property type="entry name" value="Not1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13162">
        <property type="entry name" value="CCR4-NOT TRANSCRIPTION COMPLEX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13162:SF8">
        <property type="entry name" value="CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25097">
        <property type="entry name" value="ARM_Cnot1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16415">
        <property type="entry name" value="CNOT1_CAF1_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16418">
        <property type="entry name" value="CNOT1_HEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16417">
        <property type="entry name" value="CNOT1_TTP_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12842">
        <property type="entry name" value="DUF3819"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04054">
        <property type="entry name" value="Not1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0678">Repressor</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="CCR4-NOT transcription complex subunit 1 HEAT repeat" evidence="13">
        <location>
            <begin position="263"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="domain" description="CCR4-NOT transcription complex subunit 1 TTP binding" evidence="12">
        <location>
            <begin position="467"/>
            <end position="635"/>
        </location>
    </feature>
    <feature type="domain" description="CCR4-NOT transcription complex subunit 1 CAF1-binding" evidence="11">
        <location>
            <begin position="679"/>
            <end position="899"/>
        </location>
    </feature>
    <feature type="domain" description="CCR4-NOT transcription complex subunit 1" evidence="10">
        <location>
            <begin position="1049"/>
            <end position="1191"/>
        </location>
    </feature>
    <feature type="domain" description="CCR4-NOT transcription complex subunit 1-like NOT1 connector" evidence="14">
        <location>
            <begin position="1343"/>
            <end position="1525"/>
        </location>
    </feature>
    <feature type="domain" description="CCR4-Not complex component Not1 C-terminal" evidence="9">
        <location>
            <begin position="1706"/>
            <end position="2052"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1282"/>
            <end position="1304"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="1282"/>
            <end position="1301"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00059181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00074459"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF04054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF12842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF16415"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF16417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF16418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF25097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="OBZ91327.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="2054" mass="230781" checksum="084A1DABD3810C0A" modified="2016-11-30" version="1">MTEHKDEGTESKVLKLILEAGYECCSSVNSVRELLASQINMDEKDVAQVLGCMARTHINMTGVGGTEETTGAVTWNVENFVTVVKEKLCMHVSYSLFLSKVPELNWLQVFENLDYPHFFLFDGKGLDLLVKAWVASSGPQTDFPVNVFFGEWKNLRGQLTALYQIAIAPFGTINAVKCSKKAVIGPEDFSQSSAHIRNMASQFFNNQLNSLDLIDRIIRLADTSVTADVKALLEKILIKKSPELLFMGLVQIEPFVNSVHEGMVNRLVNFYLAGNASSVMVMTKFYKVNPELFKKSMVDLYSKEPTSLTRILAFTHELKVLSTILDGQPFLFTIDLAALATRREYLNLEKWLSDKIAEHGQAFSQACLKFLGNKVRAELARQDANTAPTTVPLSMDVVNVFVKMILDSLSLPEKDLLRDIHSTYIQLSQKSIILEQTPDVSTTTELDTDTDKTLAATATAPTTTAVTLPNTHVPGEATFKQDIEDEANSYYERIYNGEITVDGMIERLSQFSKSNSPHEQDVFACMIHNLFDEYNFFPKYPNRELTITSILFGQLVEKQLVSFAPLGIALRYVLDALNNPPGSKMYNFGIQALTQFQSRLPEWPQYCAHLLQITAIQQTNPDLAHAIKYALHSRNALQQEDGDPLNQPSKELSKDSSPLVDIFTAVHVPEIAVDESIVYEAPTEAIQDKILFIINNVALNNLELKCNDLKDNLRQSAYQWFSNYLVVKRASIEPNYHELYLLLLKSVDSSLLYQHVLRETFANIKILLNSESTVSSSTERSLLKNLGAWLGGMTLAQNKPIIQKYIAFKELLLEGYDHNRLIVVIPFVCKVLEQGSKNTVFVPPNPWVTAILRLLVELYQNANLKLNLKFEIEVLCKSLSVELNNIKPSVSLKNRQPKNRITSTPAVTTATTTTTAAAALTPVNSAIAAAHMASGTNASPSIGSGTMSSIPGPSLSNIAINANIGAGLTGMGNDIISSATTLGHNGPMLKPSEEEMMMNNSPFARSSITNLISSVDANLVDEDAMSINIPNLGPYLTFNSQILMYNTQPNSKRWVLQAVTQSIREIIGPVVERSVAIASVTTKELVTKDFSMESDENRMRKAAHLMAQSLASSLALVTCKDPLRTTMANHLRVIFISNGLSEIIAEQAAMMTVADNLDLACAVIEQAAMEKVIIEVDEILMTAFSSRKKHREHRGNGQPYFDMEFFNMSHYPATLPEPLRPKPNGLQPSQLRIYEDFVRIPRSALGTVSSAGQVMEQPMPDQQQQQQQQRILRNRSDLMYLNGFNNANNNNGSNNNNNASNVLPNFDNATIQQQQQQQQQQQQFQQQANAHQLLERFIQCINELEKLIAMTNAPSFNALPMQHDIVVLIRQIPLLASSSFDKTETARMFAQKVVQLLYKSETQLGREVYVVLLERLCDISPNVGALVTSWLTHADDERKYNVPVTVALIKANLINLLEQDQELANLIDSGRLSAIDFTARLIRACLFDETPLASRQEFMASLEAISRLRGSVPESVLMLMDDMRRRMTANSSGAPTPLMPQIPQDGIQPSEENDNGLREHLRILFSEWIRIYHHPTSSEKVLNAFVIQLSQQGIFKMEDVSSLFYRICIETSIEHAIKFKQLPGQPSGLAYQPIDAFSKLVVSLLKLQQPSTPVGTPAAEAQDAGRITLFNKVLSIIVLVAAQHHEQRQQQFNQRPFLRLFNSLFSDLHAAEQEIQTVYIPILTAMSNTFNTLQPLQFPGFTFAWIQLISHRLFMPKLLLAENQKGWPAFQRLLICVFKFIGPFLEANQLKDTTRLLYRGVLRVLLVLLHDFPEFLCDYHYSLCDVIPASCIQLRNLILSAFPRNMRLPDPFTPNLKIDLLPEISQSPNILSDYTSLLLKSNIKQELDTFLTSAHAPEQFLKQLPSRLMLDKQRYNASLINVLVFYTGVVGVNESMPVNQGAPIEIFQHLLNELDSEGRYVFLNAIANQLRYPNSHTHYFSCVILFLFAETNKDFTKEQITRVLLERLIVNRPHPWGLLITFIELIKNPRYSFWSHSFTRCATDIERLFESVSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NR11</accession>
    <name>A0A1C7NR11_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_00527</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000012">
        <property type="protein sequence ID" value="OBZ91400.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NR11"/>
    <dbReference type="STRING" id="101091.A0A1C7NR11"/>
    <dbReference type="InParanoid" id="A0A1C7NR11"/>
    <dbReference type="OrthoDB" id="2420454at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047617">
        <property type="term" value="F:fatty acyl-CoA hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00586">
        <property type="entry name" value="4HBT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.129.10">
        <property type="entry name" value="Hotdog Thioesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050563">
        <property type="entry name" value="4-hydroxybenzoyl-CoA_TE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029069">
        <property type="entry name" value="HotDog_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31793">
        <property type="entry name" value="4-HYDROXYBENZOYL-COA THIOESTERASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31793:SF27">
        <property type="entry name" value="NOVEL THIOESTERASE SUPERFAMILY DOMAIN AND SAPOSIN A-TYPE DOMAIN CONTAINING PROTEIN (0610012H03RIK)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13279">
        <property type="entry name" value="4HBT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54637">
        <property type="entry name" value="Thioesterase/thiol ester dehydrase-isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005953"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ91400.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="179" mass="20059" checksum="86CB67E1188D46B3" modified="2016-11-30" version="1">MNTGSKRLSLIANHLSSGTKHSLSTNTVTASTAKKETFRSKDDYKYFLSIQTRWSDADVYGHLNNSIYYHYFDTVINDYLIKHCGLEPNRQDKKKPIGLVVASQANFYASANYPSVIHAGLRITKIGRSSVTYRVGIFEAESATACVVGGFTHVFVDPESRRPIQSLPEIYQNGMEKLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NR27</accession>
    <name>A0A1C7NR27_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">CsbD-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">A0J61_00564</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UPF0337 (CsbD) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000013">
        <property type="protein sequence ID" value="OBZ91379.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NR27"/>
    <dbReference type="STRING" id="101091.A0A1C7NR27"/>
    <dbReference type="InParanoid" id="A0A1C7NR27"/>
    <dbReference type="OrthoDB" id="9999611at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008462">
        <property type="entry name" value="CsbD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036629">
        <property type="entry name" value="YjbJ_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05532">
        <property type="entry name" value="CsbD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69047">
        <property type="entry name" value="Hypothetical protein YjbJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CsbD-like" evidence="3">
        <location>
            <begin position="7"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="8"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009129"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF05532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OBZ91379.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="85" mass="8693" checksum="DD0F6A69802FB91B" modified="2016-11-30" version="1">MSFQPSKTEAKKDQFVGDAKETVGSAVGNERLKSEGQTQHGNGLLQETTANLAGAVQGTLNTVTGTVNGALNGFVDGLNGTGNKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NR29</accession>
    <name>A0A1C7NR29_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">EamA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">A0J61_00383</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000008">
        <property type="protein sequence ID" value="OBZ91563.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NR29"/>
    <dbReference type="STRING" id="101091.A0A1C7NR29"/>
    <dbReference type="InParanoid" id="A0A1C7NR29"/>
    <dbReference type="OrthoDB" id="306876at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3730.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000620">
        <property type="entry name" value="EamA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037185">
        <property type="entry name" value="EmrE-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22911">
        <property type="entry name" value="ACYL-MALONYL CONDENSING ENZYME-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22911:SF6">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 35 MEMBER G1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00892">
        <property type="entry name" value="EamA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103481">
        <property type="entry name" value="Multidrug resistance efflux transporter EmrE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="35"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="65"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="96"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="122"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="149"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="188"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="220"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="251"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="281"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="305"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="domain" description="EamA" evidence="6">
        <location>
            <begin position="34"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="domain" description="EamA" evidence="6">
        <location>
            <begin position="189"/>
            <end position="316"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OBZ91563.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="330" mass="35746" checksum="D4035D13D2D87388" modified="2016-11-30" version="1">MSQSSVNSYTVETTPLLSERSGHERYHQKKREMTGLLYMTLSALGFSTMSLLVKLSGSNFPSFEMVFARSVVQAFFGVLGCLLLKKHPLGEPGVRGWLFVRGLAGTIGLSLFFYSITQLPLADATVVFFLGPSLTAILAALVLGEAFTLFDGICSAVCMVGVILVSKPHSLFGGQNDTTDDVSEWKRLFAVLCAFLGAVMSAVAYVTVRKIGRGAHFMVHVVYFGLVSGIVSPLGMFLLQKPVMPHGLHQYVMLILIGLTAFVGQCFLNQGLQMAPAGPGTLMRMNDVVFAFLFGILILNEYPDAYSVTGATLVVLMTSAMGIHKIYTKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NRR5</accession>
    <name>A0A1C7NRR5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Zinc finger protein C25B8.19c</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">A0J61_00274</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000005">
        <property type="protein sequence ID" value="OBZ91708.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NRR5"/>
    <dbReference type="STRING" id="101091.A0A1C7NRR5"/>
    <dbReference type="InParanoid" id="A0A1C7NRR5"/>
    <dbReference type="OrthoDB" id="6077919at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000785">
        <property type="term" value="C:chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031519">
        <property type="term" value="C:PcG protein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005667">
        <property type="term" value="C:transcription regulator complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:001102">
        <property type="entry name" value="Transcription factor IIIA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14003">
        <property type="entry name" value="TRANSCRIPTIONAL REPRESSOR PROTEIN YY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14003:SF19">
        <property type="entry name" value="YY2 TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 7" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="9">
        <location>
            <begin position="240"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="9">
        <location>
            <begin position="268"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="27"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="39"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="62"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="143"/>
            <end position="152"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OBZ91708.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="307" mass="34114" checksum="DAE18409E11D29E6" modified="2016-11-30" version="1">MNKPSLPSIQFLLQETPGPQQQPLTQHNKKHYGHRASRSVSSLPLELQSLSLHTIDEKPSPSLAQSDIYQPRQPYSGTPFPVTEKPPSWALSGDRVPNPTSTSPFNRRRSGFHGRSVSEFTLPPLTPNPPLSLPALSNTSPHNRTHHHHRRAVSANTLDFMLSPPPLPSVRAHSHSPEETHSSPMTPNSTNLNFFDKLGKDHPGNVTMINNNTTSNINTNIADTTTPAVVTTTPDPSGRYTCPYCYKKFSRPSSLRIHTYSHTGEKPFVCTEPGCGRHFSVQSNMRRHLRVHRLGRSVNNSLKTTAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NSF4</accession>
    <name>A0A1C7NSF4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Mitochondrial protein import protein mas5</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">mas5_1</name>
        <name evidence="9" type="ORF">A0J61_01623</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000054">
        <property type="protein sequence ID" value="OBZ90324.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NSF4"/>
    <dbReference type="FunCoup" id="A0A1C7NSF4">
        <property type="interactions" value="749"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NSF4"/>
    <dbReference type="InParanoid" id="A0A1C7NSF4"/>
    <dbReference type="OrthoDB" id="550424at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030544">
        <property type="term" value="F:Hsp70 protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009408">
        <property type="term" value="P:response to heat"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd10747">
        <property type="entry name" value="DnaJ_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.110:FF:000048">
        <property type="entry name" value="DnaJ family protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.10.230.10:FF:000001">
        <property type="entry name" value="DnaJ subfamily A member 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.260.20:FF:000003">
        <property type="entry name" value="DnaJ subfamily A member 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.230.10">
        <property type="entry name" value="Heat shock protein DnaJ, cysteine-rich domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.260.20">
        <property type="entry name" value="Urease metallochaperone UreE, N-terminal domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01152">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012724">
        <property type="entry name" value="DnaJ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002939">
        <property type="entry name" value="DnaJ_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018253">
        <property type="entry name" value="DnaJ_domain_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044713">
        <property type="entry name" value="DNJA1/2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008971">
        <property type="entry name" value="HSP40/DnaJ_pept-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001305">
        <property type="entry name" value="HSP_DnaJ_Cys-rich_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036410">
        <property type="entry name" value="HSP_DnaJ_Cys-rich_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43888">
        <property type="entry name" value="DNAJ-LIKE-2, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01556">
        <property type="entry name" value="DnaJ_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00684">
        <property type="entry name" value="DnaJ_CXXCXGXG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00625">
        <property type="entry name" value="JDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57938">
        <property type="entry name" value="DnaJ/Hsp40 cysteine-rich domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49493">
        <property type="entry name" value="HSP40/DnaJ peptide-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00636">
        <property type="entry name" value="DNAJ_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51188">
        <property type="entry name" value="ZF_CR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 5" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="J" evidence="7">
        <location>
            <begin position="6"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="domain" description="CR-type" evidence="8">
        <location>
            <begin position="125"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="CR-type" evidence="5">
        <location>
            <begin position="125"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="368"/>
            <end position="404"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00546"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51188"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OBZ90324.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="404" mass="44374" checksum="A635D05A17226E99" modified="2016-11-30" version="1">MVRETKFYDVLGVSPDASESELKKAYRKLALKYHPDKNPEAGDKFKEISHAYEILSDSEKRQMYDQYGEEGLNGGPGMGGMDAEDLFSQLFGGGFGGGRRGPSGPRRGKDMVHALKVSLEDLYNGKTSKLALQKHILCPKCDGKGGKEGAVQKCKTCNGQGVRLITRQMGPIVQQFQQPCDACRGLGEIINEKDKCQGCQGKKVAGEKKILEVFIDKGMRDGQKITFSGEGDQAPGIIPGDIIIVIDEKPHPHFKRQGDDLVYEAKIDLLTALAGGKFAIPHLDERVLIVNILPGEAIKPNELKVIPDEGMPAYRTHTRGHLFVKFTIEFPNPNWTSPENIAALEQILPPRPQLPSFGNKHLDEVVMADAEGYQSSSRQGSHTHDGYEDEDEQHAGPGVQCAQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NWD5</accession>
    <name>A0A1C7NWD5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">F-box/WD repeat-containing protein 7</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">Fbxw7_3</name>
        <name evidence="6" type="ORF">A0J61_00204</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000004">
        <property type="protein sequence ID" value="OBZ91734.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NWD5"/>
    <dbReference type="STRING" id="101091.A0A1C7NWD5"/>
    <dbReference type="InParanoid" id="A0A1C7NWD5"/>
    <dbReference type="OrthoDB" id="190105at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22847:SF732">
        <property type="entry name" value="F-BOX DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22847">
        <property type="entry name" value="WD40 REPEAT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12937">
        <property type="entry name" value="F-box-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00256">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="F-box" evidence="5">
        <location>
            <begin position="116"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="258"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="305"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="346"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="386"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="426"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="466"/>
            <end position="505"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="16"/>
            <end position="32"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OBZ91734.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="566" mass="64148" checksum="FF04614E3A01E3CB" modified="2016-11-30" version="1">MDLCSPEDISPPATPPNFNFSSSSSTNTTPLPTHLRNALKNSTNRPTQRLRTSFCETSLQEYNFDEDQLSHLRQLKQSFQQLTPEQKQFFLHEIINSCDNSQLTYLNSLIAPRLKIDFLKELPIEISLHILTFIDDPKTLARAATVSTLWNSLLKDEATWKSLCMKHQYRRRNSSICGGELLEPPSQRRNFSYREYFKRKYNIASAWAHGGKVKVVEDGFGDGLVTSLQYDEKYIVVGCDNHRIEVFDTNTAKKVRTLEGHEGGVWALQFKGGEKHDPERILVTGGCDRDVRVWNLNTGELRHVLRGHNSTVRCLKMKDKRIAVTGSRDTTMRVWDIQRGTCVHLLLGHQASVRCMEISGNMVVSGSYDSTARIWDLRTGRCLHVLAGHYTQIYAIAFDGHKVVTGSLDSNIRVWSAETGQCLATLHGHTSLVGQLQLSGSTLVSGGSDGCLRVWDLQHYECIQQISAHDNSVTCLQFDDRRMLSAGNDGRIKLWDIKQGRLIRSFTQLAKTVWKIQFSETKAVVLMQRRRSSSSDEGKTVMEVHDFDVEELDDYSPNSLEMTIDT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7M3U6</accession>
    <name>A0A1C7M3U6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Putative hexaprenyl pyrophosphate synthase, mitochondrial</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">COQ1_1</name>
        <name evidence="8" type="ORF">A0J61_11888</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the FPP/GGPP synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01002645">
        <property type="protein sequence ID" value="OBZ71076.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7M3U6"/>
    <dbReference type="STRING" id="101091.A0A1C7M3U6"/>
    <dbReference type="InParanoid" id="A0A1C7M3U6"/>
    <dbReference type="OrthoDB" id="9927103at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990234">
        <property type="term" value="C:transferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004659">
        <property type="term" value="F:prenyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008299">
        <property type="term" value="P:isoprenoid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006744">
        <property type="term" value="P:ubiquinone biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.600.10">
        <property type="entry name" value="Farnesyl Diphosphate Synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008949">
        <property type="entry name" value="Isoprenoid_synthase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000092">
        <property type="entry name" value="Polyprenyl_synt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12001:SF69">
        <property type="entry name" value="ALL TRANS-POLYPRENYL-DIPHOSPHATE SYNTHASE PDSS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12001">
        <property type="entry name" value="GERANYLGERANYL PYROPHOSPHATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00348">
        <property type="entry name" value="polyprenyl_synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48576">
        <property type="entry name" value="Terpenoid synthases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0414">Isoprene biosynthesis</keyword>
    <keyword evidence="5" id="KW-0460">Magnesium</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0808">Transferase</keyword>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="307"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006706"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU004466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OBZ71076.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="307" mass="34141" checksum="569AB501A345D463" modified="2016-11-30" version="1" fragment="single">MLTLTRIPKKKFLTYLRPISQLHTTRPILAISEAPLDPLTQGFKPTVLNTPFQFKGEATSWNQAISEAHHLVKENDRLIDPARLVGDDLKQIKSNISKLLGSRHPFLNTVARHYFSGEGKHVRPLLVLLIAQATSIADKTLPTGQVDFKSMDTPISYGLENITTHDVFDRKTHYTPSVSDQGCTILPTQRRLAEISEMIHTASLLHDDVIDASMTRRNLPSANASFGNKMAVLGGDFLLARASLALARLRNAECIELMATCIANLVEGEFMQLRNTKDEAGKVKTLSTFDHYMEKTYMKTGSLIALS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MPZ2</accession>
    <name>A0A1C7MPZ2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_11853</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01002589">
        <property type="protein sequence ID" value="OBZ78519.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MPZ2"/>
    <dbReference type="InParanoid" id="A0A1C7MPZ2"/>
    <dbReference type="OrthoDB" id="2317425at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="231"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ78519.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="231" mass="26769" checksum="01E1E7B31F4B6344" modified="2016-11-30" version="1" fragment="single">MKLLDLPNEVIVTIIQQAANLSAEIKSALSPWPYPEYNYASLQPIALCCRQLYTLSLPLLWKDKVFILPGPDDLQRTTDASVTATDILATPARFHHVHLGEYVRSLHRQLSNSPVFDLHNSMSIAQQVTHLRALRIDFHPQTRMAHYGLCYFAQHCPHLNELYLSHCRDTFDDFRSLIDFRPPLSSLVLESCTLKQNTYIALFELYSTSLSRIKFDQVEMEEESRHLLWQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MTT8</accession>
    <name>A0A1C7MTT8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">60S acidic ribosomal protein P2-beta</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">rpp202_0</name>
        <name evidence="5" type="ORF">A0J61_11645</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the eukaryotic ribosomal protein P1/P2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01002293">
        <property type="protein sequence ID" value="OBZ80305.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MTT8"/>
    <dbReference type="FunCoup" id="A0A1C7MTT8">
        <property type="interactions" value="436"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7MTT8"/>
    <dbReference type="InParanoid" id="A0A1C7MTT8"/>
    <dbReference type="OrthoDB" id="1227494at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022625">
        <property type="term" value="C:cytosolic large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005736">
        <property type="term" value="C:RNA polymerase I complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002182">
        <property type="term" value="P:cytoplasmic translational elongation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05833">
        <property type="entry name" value="Ribosomal_P2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.1410:FF:000002">
        <property type="entry name" value="60S acidic ribosomal protein P2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.1410">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01478">
        <property type="entry name" value="Ribosomal_L12_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038716">
        <property type="entry name" value="P1/P2_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027534">
        <property type="entry name" value="Ribosomal_P1/P2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044076">
        <property type="entry name" value="Ribosomal_P2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21141">
        <property type="entry name" value="60S ACIDIC RIBOSOMAL PROTEIN FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21141:SF5">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN P2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00428">
        <property type="entry name" value="Ribosomal_60s"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 5" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="80"/>
            <end position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005436"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OBZ80305.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="107" mass="10891" checksum="480DD11F465C4E99" modified="2016-11-30" version="1">MKYLAAYLLLNVAGKANPAAEDIKSLLSTAGIESDEERVSSLISALGDKNIEELIAEGKEKMSSVPTGGAVAAAGAASGAAAAAPAEEEKAEEKEESDDDMGFGLFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MUI3</accession>
    <name>A0A1C7MUI3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Endonuclease/exonuclease/phosphatase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_11494</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01002109">
        <property type="protein sequence ID" value="OBZ80458.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7MUI3"/>
    <dbReference type="InParanoid" id="A0A1C7MUI3"/>
    <dbReference type="OrthoDB" id="2208330at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.10.10">
        <property type="entry name" value="Endonuclease/exonuclease/phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036691">
        <property type="entry name" value="Endo/exonu/phosph_ase_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56219">
        <property type="entry name" value="DNase I-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="249"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ80458.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="249" mass="28207" checksum="2BBC52A0AA0F3454" modified="2016-11-30" version="1" fragment="single">MNLETIPGPFLSASPIPSSSTRTSFTLKRGSLNCRSIAKTASPQNRSSFIRHLRSLSFTLLALRETHADNPHVQETLHTQFQAGDSIWSAHCGLVCFSPDVMLSDAFISRCGRLINTTITHRNNLFVPFSLIVAYIPANSSERSAFLRSEFLSTLFPAIPHRHVILGDFNYTYANYFRGTPRQAPSTWLEYIDRFXFDAITTQGQLSALTFENHIDMLSTVKLSSQQVDYLPLEWTDHRLLSLHFRLLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MUK1</accession>
    <name>A0A1C7MUK1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Non-histone protein 10</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">NHP10_0</name>
        <name evidence="8" type="ORF">A0J61_11461</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01002060">
        <property type="protein sequence ID" value="OBZ80490.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MUK1"/>
    <dbReference type="STRING" id="101091.A0A1C7MUK1"/>
    <dbReference type="InParanoid" id="A0A1C7MUK1"/>
    <dbReference type="OrthoDB" id="1919336at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.30.10">
        <property type="entry name" value="High mobility group box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009071">
        <property type="entry name" value="HMG_box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036910">
        <property type="entry name" value="HMG_box_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050342">
        <property type="entry name" value="HMGB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056513">
        <property type="entry name" value="INO80F"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48112">
        <property type="entry name" value="HIGH MOBILITY GROUP PROTEIN DSP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00505">
        <property type="entry name" value="HMG_box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24245">
        <property type="entry name" value="INO80F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00398">
        <property type="entry name" value="HMG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47095">
        <property type="entry name" value="HMG-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50118">
        <property type="entry name" value="HMG_BOX_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2 4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3 4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HMG box" evidence="7">
        <location>
            <begin position="120"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="HMG box" evidence="4">
        <location>
            <begin position="120"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="103"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="226"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="6"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="163"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="226"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="269"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="284"/>
            <end position="299"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OBZ80490.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="310" mass="36548" checksum="9BEFA0ECDBFE3559" modified="2016-11-30" version="1">MTEATDPKYRQKFKDLKKRIREIEEENDLLNIKLYKARKNIRHLKLERTFLLDRMEKSSQISIDLSDNSDLGSEIYYHDEPDMHLHKIQSSHKHDGRGRIEKLMAGNNKPQRKKKDPNAPKGPGNVFFLYCRLERDKIKDEHPTENLGEVTRLLGQKWKSLTKEEKKKYYDMYKRELEEYEEAMKTYTLNGGVAPAASNSIGNEDAGMVSIVSSPAQTEMSMDFTSDHVHHHDSPEASSFMDEDMMAPPPQSEIYGHHQHHQHQHQEQLKPQQQQEQTQEQQHHTHHQQQQHHHHHHHHQPTEPTWQPTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MUL5</accession>
    <name>A0A1C7MUL5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">CCHC-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">A0J61_11399</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001989">
        <property type="protein sequence ID" value="OBZ80551.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MUL5"/>
    <dbReference type="STRING" id="101091.A0A1C7MUL5"/>
    <dbReference type="InParanoid" id="A0A1C7MUL5"/>
    <dbReference type="OrthoDB" id="8029976at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001878">
        <property type="entry name" value="Znf_CCHC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036875">
        <property type="entry name" value="Znf_CCHC_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57756">
        <property type="entry name" value="Retrovirus zinc finger-like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50158">
        <property type="entry name" value="ZF_CCHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="CCHC-type" evidence="3">
        <location>
            <begin position="277"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="247"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="247"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OBZ80551.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="353" mass="41844" checksum="FD33D7E8E86F6EDA" modified="2016-11-30" version="1" fragment="single">RTKRSSTGTSFGDKKFDEQVPLATTYGLPPTHNNDQGTTDMKNMRRTILELQEQLWQVTLQQDKKTSVLRIPQDKTNNPDGMLRDSVDQDTIKERRRRVRLPAFTLSDMQKAREWLMKYNSLTHHICFSETEKLADLEVRLKGDALSSFIYLPEEDKRTWKRLERAQCEWYSLNRSYREVARKAEVHLEVMLISYLKAVVNPEMRKAIVYRGPKTYTQAVDICVEVKTDFLTDQYHPTVKTLTEFTQQNYQSRDNRQKGNSQQSERGWDQVQEKRSCFTCKKVGHLKIDCWLNKKKNIRHHNNQETTNQQEETPVEEIINIFDYLFGNNQQEQTAQQERNRFKIRIKCNNQKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MUR8</accession>
    <name>A0A1C7MUR8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_11326</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001910">
        <property type="protein sequence ID" value="OBZ80625.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MUR8"/>
    <dbReference type="STRING" id="101091.A0A1C7MUR8"/>
    <dbReference type="InParanoid" id="A0A1C7MUR8"/>
    <dbReference type="OrthoDB" id="2290118at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003714">
        <property type="term" value="F:transcription corepressor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013927">
        <property type="entry name" value="TF_Opi1_Ccg-8"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08618">
        <property type="entry name" value="Opi1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="97"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ80625.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="97" mass="10762" checksum="AFC9C306512C50E1" modified="2016-11-30" version="1" fragment="single">MSKPSSAMSITEICHKQEFGNESIQLPPSQPQESFHFISRLPLVNSALRAYESSSSVVKYGAEMIESYAGPIYDKLGYDRRLKSEIAEDDDTLAATT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MV72</accession>
    <name>A0A1C7MV72_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Nucleoporin-like protein amo1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">amo1</name>
        <name evidence="9" type="ORF">A0J61_11166</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001729">
        <property type="protein sequence ID" value="OBZ80785.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MV72"/>
    <dbReference type="STRING" id="101091.A0A1C7MV72"/>
    <dbReference type="InParanoid" id="A0A1C7MV72"/>
    <dbReference type="OrthoDB" id="20729at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.1000.10">
        <property type="entry name" value="Zinc finger, CCCH-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051767">
        <property type="entry name" value="Nucleoporin_NUP42"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041367">
        <property type="entry name" value="Znf-CCCH_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000571">
        <property type="entry name" value="Znf_CCCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036855">
        <property type="entry name" value="Znf_CCCH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46527:SF1">
        <property type="entry name" value="NUCLEOPORIN NUP42"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46527">
        <property type="entry name" value="NUCLEOPORIN-LIKE PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18044">
        <property type="entry name" value="zf-CCCH_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00356">
        <property type="entry name" value="ZnF_C3H1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90229">
        <property type="entry name" value="CCCH zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50103">
        <property type="entry name" value="ZF_C3H1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 6" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C3H1-type" evidence="8">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="6">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="294"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="313"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OBZ80785.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="313" mass="31480" checksum="2ED7FBE1D3AD340D" modified="2016-11-30" version="1" fragment="single">MAICKFYASGNCRYGSSCNFEHIGAQQNRWGTNNTTNVAASKYNETSLKSDLTEARPQWKLSVYGPAKEEPNLIVGTDRSCEEDRYLYYTSMRTTNNTSQYMASYEQLFNQMEAQTNAIVNNPTAAIQHYEKEKTTRASPFSGTGPASNSLAPFTGSTGGAFGTTGGAFGKPSAFGSTGGGGGAFGQSSAFGQTATSSAFGGNSSFGSTNTLGSGSAFGSTSTLGNNNSAFGSTSALGSGSAFGSAGALNSGSAFGSANTLGSGSAFGSTSALGGNSAFGKPSAFGQTASQASAFGSNTTTGSAFGSTNTLGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MVC2</accession>
    <name>A0A1C7MVC2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Tubulin--tyrosine ligase-like protein 12</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">ttll-12</name>
        <name evidence="3" type="ORF">A0J61_11243</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001818">
        <property type="protein sequence ID" value="OBZ80708.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MVC2"/>
    <dbReference type="STRING" id="101091.A0A1C7MVC2"/>
    <dbReference type="InParanoid" id="A0A1C7MVC2"/>
    <dbReference type="OrthoDB" id="2127950at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.470.20">
        <property type="entry name" value="ATP-grasp fold, B domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057954">
        <property type="entry name" value="SET_TTL12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004344">
        <property type="entry name" value="TTL/TTLL_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027749">
        <property type="entry name" value="TTLL12"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46088">
        <property type="entry name" value="TUBULIN--TYROSINE LIGASE-LIKE PROTEIN 12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46088:SF1">
        <property type="entry name" value="TUBULIN--TYROSINE LIGASE-LIKE PROTEIN 12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25556">
        <property type="entry name" value="SET_TTL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03133">
        <property type="entry name" value="TTL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56059">
        <property type="entry name" value="Glutathione synthetase ATP-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51221">
        <property type="entry name" value="TTL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0436">Ligase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tubulin--tyrosine ligase-like protein 12 SET-like" evidence="2">
        <location>
            <begin position="50"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="15"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="25"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF25556"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ80708.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="531" mass="61498" checksum="9A2935C91EE56E59" modified="2016-11-30" version="1" fragment="single">DPEAKAEADRLHDQVMNQVLSSGKPQEKEERERLERRDRREKEWFVRRAQAVYRAMWSFLQTYTYSILQQDGQPTSQTAWYVNDEVGSALAHSEDPNVVCVPFIFSRGASGMIPYSVFFPIKDMEAGELMTVDLRPKNLTRTSDQEAYLLAFENRLTTAIDKQPLIDLYRAHQASLEQRQPPSSTWTSDEAKKALLKHTKTKTSETMTVYTDAPFVQQFLKLDHVKFTDDLSRADIIWISQDFSEWDTLSAQQTINQLPNERCLTFKHQLAQLMQETLGSPGWFLPTYNVMSQLAELAGHYLSEETRLWITKPWNMARGLGLDITDNLAQLIRQHDHPIPKIAQPYLTRPCLYNGKKFDLRYIVLVRQTEPNLVALVYNMFWTRLANKKFSLDQLDDYECQFTVMNYTDFEMTQLDHQSFIRNIEKQHQVQWEPVQQAIYGAIKDVLMTAVHSSQPLGLLGADKGKADTFAMYGFDVMLTDDFKPIVVEVNFSPDCTRPCQYDPEFVNNLFSVVDSRFDRLEEGLKAFTVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MVC5</accession>
    <name>A0A1C7MVC5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_11595</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01002233">
        <property type="protein sequence ID" value="OBZ80356.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MVC5"/>
    <dbReference type="InParanoid" id="A0A1C7MVC5"/>
    <dbReference type="OrthoDB" id="2290280at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="173"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ80356.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="173" mass="20004" checksum="98D229A15DD7FFB4" modified="2016-11-30" version="1" fragment="single">GDSESTIDYIYASPVLFHHLHSSTVDFINSFTFASHHQGPGLWRAHPNLAHNRYFTEKLTSKLDEFHYLLRSSTPPLSPQEQWDDIKVLAKMIAQQVVRPYQRQLTRLHRKRNKLLREHKLTSILPLRLAAIEKQIGIIQQGRVETLALRAGKHWRDNGETSTGYLKSTISSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MWB5</accession>
    <name>A0A1C7MWB5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_11205</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001775">
        <property type="protein sequence ID" value="OBZ80746.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MWB5"/>
    <dbReference type="InParanoid" id="A0A1C7MWB5"/>
    <dbReference type="OrthoDB" id="2281860at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ80746.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="218" mass="24349" checksum="9A9F2E1AE2F78851" modified="2016-11-30" version="1">MSNNSQNQNLSSPYSVYQTQANEALRRNETVASVLQLQAGTQCNNTKKAHDQRQSKFIQYASDICVTEEKIVDFLKEAVLKEAVVKEAVVKEAVVKEAVVKEAVVKEGNTRSTQRGGLQANGKPYPLSMSSIDQYVKAAIDIYAVQKPTSVGLINFENPRGSLLKTYLRASRQQEADRMRNSYEDRGAGTLQDGYTPDELIRVSMYYFTSAAESMMRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MX18</accession>
    <name>A0A1C7MX18_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Catalase</fullName>
            <ecNumber evidence="12">1.11.1.6</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="primary">catA</name>
        <name evidence="15" type="ORF">A0J61_10506</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8 13">Catalyzes the degradation of hydrogen peroxide (H(2)O(2)) generated by peroxisomal oxidases to water and oxygen, thereby protecting cells from the toxic effects of hydrogen peroxide.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9 12">
            <text>2 H2O2 = O2 + 2 H2O</text>
            <dbReference type="Rhea" id="RHEA:20309"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16240"/>
            <dbReference type="EC" id="1.11.1.6"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="11">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1 12">Belongs to the catalase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.11.1.6" evidence="12"/>
    <dbReference type="EMBL" id="LUGH01001206">
        <property type="protein sequence ID" value="OBZ81445.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MX18"/>
    <dbReference type="FunCoup" id="A0A1C7MX18">
        <property type="interactions" value="302"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7MX18"/>
    <dbReference type="InParanoid" id="A0A1C7MX18"/>
    <dbReference type="OrthoDB" id="6880011at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005777">
        <property type="term" value="C:peroxisome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004096">
        <property type="term" value="F:catalase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042744">
        <property type="term" value="P:hydrogen peroxide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042542">
        <property type="term" value="P:response to hydrogen peroxide"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd08156">
        <property type="entry name" value="catalase_clade_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.180.10:FF:000001">
        <property type="entry name" value="Catalase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.180.10">
        <property type="entry name" value="Catalase core domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018028">
        <property type="entry name" value="Catalase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040333">
        <property type="entry name" value="Catalase_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024708">
        <property type="entry name" value="Catalase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024711">
        <property type="entry name" value="Catalase_clade1/3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011614">
        <property type="entry name" value="Catalase_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002226">
        <property type="entry name" value="Catalase_haem_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010582">
        <property type="entry name" value="Catalase_immune_responsive"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020835">
        <property type="entry name" value="Catalase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11465">
        <property type="entry name" value="CATALASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11465:SF9">
        <property type="entry name" value="CATALASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00199">
        <property type="entry name" value="Catalase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06628">
        <property type="entry name" value="Catalase-rel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF038928">
        <property type="entry name" value="Catalase_clade1-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00067">
        <property type="entry name" value="CATALASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM01060">
        <property type="entry name" value="Catalase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56634">
        <property type="entry name" value="Heme-dependent catalase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00437">
        <property type="entry name" value="CATALASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00438">
        <property type="entry name" value="CATALASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51402">
        <property type="entry name" value="CATALASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 11 12" id="KW-0349">Heme</keyword>
    <keyword evidence="7 12" id="KW-0376">Hydrogen peroxide</keyword>
    <keyword evidence="6 11 12" id="KW-0408">Iron</keyword>
    <keyword evidence="4 11 12" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 12" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="2 12" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Catalase core" evidence="14">
        <location>
            <begin position="7"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="active site" evidence="10">
        <location>
            <position position="54"/>
        </location>
    </feature>
    <feature type="active site" evidence="10">
        <location>
            <position position="127"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="11">
        <location>
            <position position="337"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00044729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00049254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR038928-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR038928-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU000498"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU004142"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="SMART" id="SM01060"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="OBZ81445.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="482" mass="54400" checksum="5FA46037264CA0B4" modified="2016-11-30" version="1">MSNPILTTSNGCPVDNDQTSITAGVNGPVLISDFHLIDKISHFDRERIPERVVHAKGAGAHGEFVVTHDVSHLTKAKFLNGIGKKTPMFARFSTVGGEKGSADTARDPRGFSLKFYTEEGNIDVVGNNTPVFFIRDPSKFPDFIHTQKRDPKSNLKNPEAKWDFYTSVPESLHQVTILMSNYGTPDGFRFMHGYGSHTFKLVDNNGKFKYFKWHFKSKQGSKNLKAKKALELEGSDPDYATRDMFEAIERGDYPSWDVYFQVMEPEDAKKYRWNIFDVTKVWPHKDYPLIPVGTFTLNRNPENYFAETEQAAFSPSHIVPGIDVSADRMLQGRLFSYPDAHRYRLGVNYHQIPINRPIAPVNNYQRDGFMTVDGNGGSSANYGPNSTGGPVQNNIIGSTFAPEEVEGMTGRFSYQVTDDDFVQPGNLYRLMSEEDKDDLAENIVEELVLCKQEIVDKALAMFERADPDYRARVEKALSKAKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MX28</accession>
    <name>A0A1C7MX28_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_10572</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001242">
        <property type="protein sequence ID" value="OBZ81377.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MX28"/>
    <dbReference type="InParanoid" id="A0A1C7MX28"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="25"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="31"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="42"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ81377.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="124" mass="13969" checksum="020F24E6F7AB4A97" modified="2016-11-30" version="1">MNVVEVHHTSALHTSNKYYDINAVKRKTKSDQNSYDQNNTHQPKERRLEEYHTSAGSSFNGNVHPYVGPTTSVQTNADIQIHTENQNRGALISQIRQKQNPVHQNSLAAILTLDIVNRHASISV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MXC3</accession>
    <name>A0A1C7MXC3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Large ribosomal subunit protein mL49</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">img2_1</name>
        <name evidence="7" type="ORF">A0J61_10465</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the mitochondrion-specific ribosomal protein mL49 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001187">
        <property type="protein sequence ID" value="OBZ81487.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MXC3"/>
    <dbReference type="FunCoup" id="A0A1C7MXC3">
        <property type="interactions" value="73"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7MXC3"/>
    <dbReference type="InParanoid" id="A0A1C7MXC3"/>
    <dbReference type="OrthoDB" id="19439at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005762">
        <property type="term" value="C:mitochondrial large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.780.10">
        <property type="entry name" value="SUI1-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007740">
        <property type="entry name" value="Ribosomal_mL49"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13477:SF0">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN ML49"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13477">
        <property type="entry name" value="MITOCHONDRIAL 39S RIBOSOMAL PROTEIN L49"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05046">
        <property type="entry name" value="Img2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56801">
        <property type="entry name" value="Acetyl-CoA synthetase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 7" id="KW-0689">Ribosomal protein</keyword>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="193"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00035191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OBZ81487.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="193" mass="22119" checksum="54D91ECF07DB38E4" modified="2016-11-30" version="1" fragment="single">MAAIVLKEGTAIDFKDLRSYLQKNLPKYAVPLFLRFVPSMEITGTFKQQKVAFRNQGIDLTKIPESEPVYWLKEDTYVPFTLEDFAKIDVAKKMLRHIAQSTFQSTKRFYSTPAYTISRTTNKGLPVYSEYKNGNTRLLTIIRRIQGDSNALAKDLVNDFPEAVVQVKPTTKHVVIKGNHVNEIKEWLISKGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MXX0</accession>
    <name>A0A1C7MXX0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Protein phosphatase 2C 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">ptc2_4</name>
        <name evidence="2" type="ORF">A0J61_10279</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001100">
        <property type="protein sequence ID" value="OBZ81672.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MXX0"/>
    <dbReference type="STRING" id="101091.A0A1C7MXX0"/>
    <dbReference type="InParanoid" id="A0A1C7MXX0"/>
    <dbReference type="OrthoDB" id="10264738at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004722">
        <property type="term" value="F:protein serine/threonine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00143">
        <property type="entry name" value="PP2Cc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.40.10">
        <property type="entry name" value="PPM-type phosphatase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015655">
        <property type="entry name" value="PP2C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036457">
        <property type="entry name" value="PPM-type-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001932">
        <property type="entry name" value="PPM-type_phosphatase-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13832:SF827">
        <property type="entry name" value="PROTEIN PHOSPHATASE 1L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13832">
        <property type="entry name" value="PROTEIN PHOSPHATASE 2C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00481">
        <property type="entry name" value="PP2C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81606">
        <property type="entry name" value="PP2C-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51746">
        <property type="entry name" value="PPM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PPM-type phosphatase" evidence="1">
        <location>
            <begin position="1"/>
            <end position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51746"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ81672.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="155" mass="17450" checksum="01D6919062A49CE5" modified="2016-11-30" version="1">MESSVIHYKIYKGSLALSRAIGDFKFKQNTQLTPDLQAVTAEPDISEHLLTDHDEFVVLACDGIWDCLNSQQVVDFIRCKLCEHKSLGPICEELMDYCLAESGNLSGIGCDNMTVIIVAFLRRRKPQQWYDWMASKTAPPMPAKKAILLAKSIKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MYX5</accession>
    <name>A0A1C7MYX5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_09825</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000947">
        <property type="protein sequence ID" value="OBZ82125.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MYX5"/>
    <dbReference type="STRING" id="101091.A0A1C7MYX5"/>
    <dbReference type="InParanoid" id="A0A1C7MYX5"/>
    <dbReference type="OrthoDB" id="2289822at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="309"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ82125.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="309" mass="34645" checksum="CAB7D398680AA013" modified="2016-11-30" version="1" fragment="single">MKQLVAKWQQDVSRRIGKMWKRLYTFRQYWTALHMNSRVTVCCISTTTGDKLAKSAERGKYRTSTRQMAYASLGTLTKIYVDEDCSEMLIEGSSLTEAQQSLAKSASSNDQAFDLNVHPKHRTEEENMIQIGVVPGKPYDLNSYLASLIKEVNDMYSKGVIIQKDGVEKYCGNVAIVGITGDIPGISELMVFAGHTSTFGCRVCLSEGYSPVPVSSHGKYFPDLGPIRTAESLINGDPNFDMYGLPDDYANLPTFTDSFFFFGDELHMLGHGIGHLIYKLIHPSTFDFYRALNSSSYTFNFIDGFSRKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MZ18</accession>
    <name>A0A1C7MZ18_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Mitochondrial distribution and morphology protein 10</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Mitochondrial inheritance component MDM10</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6 7" type="primary">MDM10</name>
        <name evidence="7" type="ORF">A0J61_09944</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis and may function in phospholipid exchange. MDM10 is involved in the late assembly steps of the general translocase of the mitochondrial outer membrane (TOM complex). Functions in the TOM40-specific route of the assembly of outer membrane beta-barrel proteins, including the association of TOM40 with the receptor TOM22 and small TOM proteins. Can associate with the SAM(core) complex as well as the MDM12-MMM1 complex, both involved in late steps of the major beta-barrel assembly pathway, that is responsible for biogenesis of all outer membrane beta-barrel proteins. May act as a switch that shuttles between both complexes and channels precursor proteins into the TOM40-specific pathway. Plays a role in mitochondrial morphology and in the inheritance of mitochondria.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Component of the ER-mitochondria encounter structure (ERMES) or MDM complex, composed of MMM1, MDM10, MDM12 and MDM34. Associates with the mitochondrial outer membrane sorting assembly machinery SAM(core) complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Mitochondrion outer membrane</location>
            <topology evidence="6">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <text evidence="6">The ERMES/MDM complex localizes to a few discrete foci (around 10 per single cell), that represent mitochondria-endoplasmic reticulum junctions. These foci are often found next to mtDNA nucleoids.</text>
    </comment>
    <comment type="domain">
        <text evidence="6">Lacks alpha-helical transmembrane segments, suggesting that it resides in the membrane via beta-sheet conformations similar to those predicted for other outer membrane proteins and porin.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the MDM10 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000978">
        <property type="protein sequence ID" value="OBZ82008.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MZ18"/>
    <dbReference type="FunCoup" id="A0A1C7MZ18">
        <property type="interactions" value="64"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7MZ18"/>
    <dbReference type="InParanoid" id="A0A1C7MZ18"/>
    <dbReference type="OrthoDB" id="2103793at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032865">
        <property type="term" value="C:ERMES complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001401">
        <property type="term" value="C:SAM complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051654">
        <property type="term" value="P:establishment of mitochondrion localization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070096">
        <property type="term" value="P:mitochondrial outer membrane translocase complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990456">
        <property type="term" value="P:mitochondrion-endoplasmic reticulum membrane tethering"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015914">
        <property type="term" value="P:phospholipid transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045040">
        <property type="term" value="P:protein insertion into mitochondrial outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03102">
        <property type="entry name" value="Mdm10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027539">
        <property type="entry name" value="Mdm10"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28035">
        <property type="entry name" value="MITOCHONDRIAL DISTRIBUTION AND MORPHOLOGY PROTEIN 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28035:SF1">
        <property type="entry name" value="MITOCHONDRIAL DISTRIBUTION AND MORPHOLOGY PROTEIN 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12519">
        <property type="entry name" value="MDM10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 6" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="3 6" id="KW-1000">Mitochondrion outer membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1 6" id="KW-1134">Transmembrane beta strand</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022452"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OBZ82008.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="378" mass="42711" checksum="3082A5483E890B9A" modified="2016-11-30" version="1">MNDFMEYCLKWYYRSSGWNEENQYANLCSWSRAILDFQTPRGLSLLVSRLPTKQFKPSYTLNALPALNGSLGYLYTSRPLDVKTSATVDFQDLIDRFRVIVHTSKKSYADYRAVGFIDITSLDFEANPDYLLYGRMFFPGARLEAMYVRRLSEHLQCSVTAVNSPHTSIFPQVAMQLQYDVGKWSSDCSYTSDDGLLGVRALYNFGQPASSSGLISLGTEIYYGVRDKSGGLSTGIRYQTSPLSNSAPTSCTFILSPIVGRMSTSYVSQISEQLVMCSRFDFSIYSYESDLDLGFEYRTKSKKPTVVEKKEEEGVVTLTADRTEKLESLIKARWGFAKGLALMWEGRFKNALFSFGLTADLRTTNPIRTIGLEVQYFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MZD2</accession>
    <name>A0A1C7MZD2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Mediator of RNA polymerase II transcription subunit 8</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Mediator complex subunit 8</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">MED8</name>
        <name evidence="2" type="ORF">A0J61_09842</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Component of the Mediator complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the Mediator complex subunit 8 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000951">
        <property type="protein sequence ID" value="OBZ82108.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MZD2"/>
    <dbReference type="FunCoup" id="A0A1C7MZD2">
        <property type="interactions" value="76"/>
    </dbReference>
    <dbReference type="InParanoid" id="A0A1C7MZD2"/>
    <dbReference type="OrthoDB" id="5568181at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016592">
        <property type="term" value="C:mediator complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003712">
        <property type="term" value="F:transcription coregulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.1710">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019364">
        <property type="entry name" value="Mediatior_Med8_fun/met"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10232">
        <property type="entry name" value="Med8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0010">Activator</keyword>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU364144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ82108.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="247" mass="28898" checksum="521247710EFA14AD" modified="2016-11-30" version="1">MEPAQIQATLDPHTYQELEALKGKLWSLQETFSTHLTYLKEPKYPFTWPDLLNKFNMLTAKFATLSEDFHSYTTTGSNATLPKLMVHPYIPTTTEQETNILSVLLRTKLIPDIERLEAETQAAIAQEMKTESVHEQRLDDEQLIRNQLDQWNQLLERHDRLAIDATQFVTELASDHRPNFLLRYEHQLDEDEEEESKEAEWQKLGFPTEDIWKRWKLESMMNFYSSGKNELVGSDVKKLATNSNPKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MZR2</accession>
    <name>A0A1C7MZR2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Sulfhydryl oxidase</fullName>
            <ecNumber evidence="6">1.8.3.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">Gfer_1</name>
        <name evidence="8" type="ORF">A0J61_09699</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>2 R'C(R)SH + O2 = R'C(R)S-S(R)CR' + H2O2</text>
            <dbReference type="Rhea" id="RHEA:17357"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16240"/>
            <dbReference type="ChEBI" id="CHEBI:16520"/>
            <dbReference type="ChEBI" id="CHEBI:17412"/>
            <dbReference type="EC" id="1.8.3.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 6">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.8.3.2" evidence="6"/>
    <dbReference type="EMBL" id="LUGH01000912">
        <property type="protein sequence ID" value="OBZ82251.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MZR2"/>
    <dbReference type="FunCoup" id="A0A1C7MZR2">
        <property type="interactions" value="312"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7MZR2"/>
    <dbReference type="InParanoid" id="A0A1C7MZR2"/>
    <dbReference type="OrthoDB" id="17199at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016971">
        <property type="term" value="F:flavin-dependent sulfhydryl oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.310">
        <property type="entry name" value="ERV/ALR sulfhydryl oxidase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039799">
        <property type="entry name" value="ALR/ERV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036774">
        <property type="entry name" value="ERV/ALR_sulphydryl_oxid_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017905">
        <property type="entry name" value="ERV/ALR_sulphydryl_oxidase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12645">
        <property type="entry name" value="ALR/ERV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12645:SF0">
        <property type="entry name" value="FAD-LINKED SULFHYDRYL OXIDASE ALR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04777">
        <property type="entry name" value="Evr1_Alr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69000">
        <property type="entry name" value="FAD-dependent thiol oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51324">
        <property type="entry name" value="ERV_ALR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="3 6" id="KW-0274">FAD</keyword>
    <keyword evidence="2 6" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4 6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ERV/ALR sulfhydryl oxidase" evidence="7">
        <location>
            <begin position="14"/>
            <end position="112"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU371123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OBZ82251.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="122" mass="14320" checksum="B5CBB296F3E88D0D" modified="2016-11-30" version="1">MTTQEKTNWQKENCPVDVEQLGRATWTLLHTAAAYYPDRPAPSQMESMRAFMTSIMEHYPCFGEEFKMYLEQEPVRVGNRKKLSAWLCRQHNKVNEKLGKPTFDCSLVFDRWLQGINKACEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MZX3</accession>
    <name>A0A1C7MZX3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Zinc finger protein 42</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">Zfp42</name>
        <name evidence="13" type="ORF">A0J61_09608</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000890">
        <property type="protein sequence ID" value="OBZ82342.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MZX3"/>
    <dbReference type="STRING" id="101091.A0A1C7MZX3"/>
    <dbReference type="InParanoid" id="A0A1C7MZX3"/>
    <dbReference type="OrthoDB" id="6077919at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000785">
        <property type="term" value="C:chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031519">
        <property type="term" value="C:PcG protein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005667">
        <property type="term" value="C:transcription regulator complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000062">
        <property type="entry name" value="RB-associated KRAB zinc finger protein-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000104">
        <property type="entry name" value="Transcriptional repressor protein YY1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14003">
        <property type="entry name" value="TRANSCRIPTIONAL REPRESSOR PROTEIN YY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14003:SF19">
        <property type="entry name" value="YY2 TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="8" id="KW-0804">Transcription</keyword>
    <keyword evidence="6" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 10" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="12">
        <location>
            <begin position="193"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="12">
        <location>
            <begin position="221"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="152"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="155"/>
            <end position="177"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="OBZ82342.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="250" mass="27944" checksum="A04DAE26A2E7D7D3" modified="2016-11-30" version="1">MTSPVAYHASLLSNHTYPVSPLEYSPTCSYSSIPPRSYSQHTDYQKGTLSPLTTGYPLGSFPLLTPPTLEPYLFYSQQQDVTYNYFGNRAHSFDSMCPSPNSQPCFQCQFTPPSIPQSNLNLYHSYPSTLSSPSSSLSPPPPSRVYRHNKRQFTSRNSLDSLSSASSSCSKQSQNKLSSDELPSPTSNAPRRYKCNLCTKRFTRPSSLATHMHSHTGEKPYECVVEGCGRRFSVVSNLRRHAKIHTNNNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N0A1</accession>
    <name>A0A1C7N0A1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 11">Condensin complex subunit 2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">cnd2</name>
        <name evidence="13" type="ORF">A0J61_09366</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Chromosome</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 11">Belongs to the CND2 (condensin subunit 2) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000833">
        <property type="protein sequence ID" value="OBZ82585.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N0A1"/>
    <dbReference type="FunCoup" id="A0A1C7N0A1">
        <property type="interactions" value="668"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N0A1"/>
    <dbReference type="InParanoid" id="A0A1C7N0A1"/>
    <dbReference type="OrthoDB" id="362021at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000796">
        <property type="term" value="C:condensin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003682">
        <property type="term" value="F:chromatin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007076">
        <property type="term" value="P:mitotic chromosome condensation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022816">
        <property type="entry name" value="Condensin_barren_su2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13108">
        <property type="entry name" value="CONDENSIN COMPLEX SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13108:SF9">
        <property type="entry name" value="CONDENSIN COMPLEX SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05786">
        <property type="entry name" value="Cnd2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF017126">
        <property type="entry name" value="Condensin_H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 11" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="7 11" id="KW-0132">Cell division</keyword>
    <keyword evidence="5" id="KW-0158">Chromosome</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9 11" id="KW-0226">DNA condensation</keyword>
    <keyword evidence="8 11" id="KW-0498">Mitosis</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="115"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="225"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="381"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="454"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="11"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="12">
        <location>
            <begin position="230"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="289"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="301"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="12">
        <location>
            <begin position="382"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="464"/>
            <end position="478"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00016065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023067"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRNR" id="PIRNR017126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="OBZ82585.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="769" mass="88045" checksum="1610649B7801D340" modified="2016-11-30" version="1">METTRTRRPLSNSTANNASTSNEPLAVQATVPALTPAQMYSNFEEWIKMCTDNKVNATNTWTFALIDYFHEMTFIREGDSINFQKASCTLDGCVKIYTSRVDSVATETGKLLSGLADSSNADDDDSRQPTERRVRRKTQRSEATLLKDFSSISLKKFDLDFTVDPLFKKTSADFDEGGARGLLLNHLGIDQQCKIIFDASDATVECELEELDGEHTTIEHIEANEQAAAESEEEQESDEEAEDEEVENKEAENEEEGTAEKNTAEGEAEDEVMLDAPETTKEDAEDQIMTENNQDQPMTDNKPENETSKEEEDKRIEIFRLKAKLPKMEALSEFHIVPFLKGYDFFSDNFTIPDLEHDEDEEDMAPPAREESMAPVGADAFQFDDDFDFGGDDIDPFNDTPFDSNQPHEDEEDEIEAPPKSFEHDFLSALMTSGEHDMFDYFDSTLVKNWAGPEHWKLRRPPTQKKQSADPSQDAGQQNRRKSRTTEVFWLPFKEIKEDEENDVFEKSSRKPLMGKDTIQKMTEHLLPNDIQFSSKLLLQYSLKPAIPKKTRHRRLDAVKSLVDKEQPKEQEQDNEGGIASADIEFWAEQTQDYMDDAPDFDSGMPMDDDIQLDQTMLTAFEDTSFYHDNYDDPEVSVLYGDELITHHTLKKTKPLYVNYARTAKRVDIKKLKDNLWKVLTSHHQDEKVQGEQKFSDIVHHLKKLYPPKAMRDISVPFCFICLLHLANEKDLSIRGPMIDEDDDFVLGEQQDWMKDEAILSEVTIVQNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N0R6</accession>
    <name>A0A1C7N0R6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Oxidative stress response two-component system protein SSK1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">SSK1</name>
        <name evidence="6" type="ORF">A0J61_09731</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000924">
        <property type="protein sequence ID" value="OBZ82219.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N0R6"/>
    <dbReference type="FunCoup" id="A0A1C7N0R6">
        <property type="interactions" value="75"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N0R6"/>
    <dbReference type="InParanoid" id="A0A1C7N0R6"/>
    <dbReference type="OrthoDB" id="21225at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd17546">
        <property type="entry name" value="REC_hyHK_CKI1_RcsC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45339">
        <property type="entry name" value="HYBRID SIGNAL TRANSDUCTION HISTIDINE KINASE J"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45339:SF1">
        <property type="entry name" value="HYBRID SIGNAL TRANSDUCTION HISTIDINE KINASE J"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="CheY-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0902">Two-component regulatory system</keyword>
    <feature type="domain" description="Response regulatory" evidence="5">
        <location>
            <begin position="173"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="120"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="442"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="14"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="456"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="475"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="3">
        <location>
            <position position="222"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="484"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OBZ82219.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="484" mass="52884" checksum="14BDBCAEA7CC13E2" modified="2016-11-30" version="1" fragment="single">PVSGIFNPPPADNYFTSHQPQSQHQEQLSPSFSTARRRSANGNTAAEDYLTAKHLPLMNALGVASSTSPAVAIAAASVAAAISNHTTPVDDSMVHKEGLNSPVAIPEEKKAKTEIIPVDNAPDLAAPSPANPVVDESKDGLPKKKVSNTIKLHKKKKKSKGTPFADVVSPPINVLIVEDNIINQAILSTWMKKHKIKFSVASNGKEAVDKWKKGGFHLILMDIQLPVMNGIEATKMIRSIEKEQKIGVLPMSSSFLRQQQAVAAATAASLLNQQESTSLEQEVSAAATEIQRMQEEENVVVPSIFRSPVIIVALTASSLESDRHTALAAGCNDFLTKPVSLEWLEKKIIEWGCMQALIDFEGWRRWKKKSNAEDVKKTSAMKEALDAKGLTQEQIETEKKRIESLSRMPNKQGVMLPGVSNLMKSRRSSSIYDLNHNLKKSQDSNKLLKPSRSESDTQVVLRTSSDPQIGSGLDDQDKSKKILP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N156</accession>
    <name>A0A1C7N156_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Aminopeptidase</fullName>
            <ecNumber evidence="11">3.4.11.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="primary">ape1</name>
        <name evidence="16" type="ORF">A0J61_09137</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="9 11">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="9 11">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 11">Belongs to the peptidase M1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.11.-" evidence="11"/>
    <dbReference type="EMBL" id="LUGH01000782">
        <property type="protein sequence ID" value="OBZ82812.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N156"/>
    <dbReference type="FunCoup" id="A0A1C7N156">
        <property type="interactions" value="614"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N156"/>
    <dbReference type="InParanoid" id="A0A1C7N156"/>
    <dbReference type="OrthoDB" id="10031169at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070006">
        <property type="term" value="F:metalloaminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042277">
        <property type="term" value="F:peptide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043171">
        <property type="term" value="P:peptide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd09601">
        <property type="entry name" value="M1_APN-Q_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.390.10:FF:000001">
        <property type="entry name" value="Aminopeptidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.50.20:FF:000002">
        <property type="entry name" value="Aminopeptidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.1730:FF:000002">
        <property type="entry name" value="Aminopeptidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.50.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1910">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.390.10">
        <property type="entry name" value="Neutral Protease Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1730">
        <property type="entry name" value="tricorn interacting facor f3 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045357">
        <property type="entry name" value="Aminopeptidase_N-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042097">
        <property type="entry name" value="Aminopeptidase_N-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024571">
        <property type="entry name" value="ERAP1-like_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034016">
        <property type="entry name" value="M1_APN-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050344">
        <property type="entry name" value="Peptidase_M1_aminopeptidases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014782">
        <property type="entry name" value="Peptidase_M1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027268">
        <property type="entry name" value="Peptidase_M4/M1_CTD_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11533">
        <property type="entry name" value="PROTEASE M1 ZINC METALLOPROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11533:SF174">
        <property type="entry name" value="PUROMYCIN-SENSITIVE AMINOPEPTIDASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11838">
        <property type="entry name" value="ERAP1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01433">
        <property type="entry name" value="Peptidase_M1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17900">
        <property type="entry name" value="Peptidase_M1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63737">
        <property type="entry name" value="Leukotriene A4 hydrolase N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55486">
        <property type="entry name" value="Metalloproteases ('zincins'), catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 11 16" id="KW-0031">Aminopeptidase</keyword>
    <keyword evidence="5 11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 9 11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 11" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="3 11" id="KW-0645">Protease</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 9 11" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Aminopeptidase N-like N-terminal" evidence="15">
        <location>
            <begin position="19"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M1 membrane alanine aminopeptidase" evidence="13">
        <location>
            <begin position="285"/>
            <end position="501"/>
        </location>
    </feature>
    <feature type="domain" description="ERAP1-like C-terminal" evidence="14">
        <location>
            <begin position="573"/>
            <end position="900"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="188"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="188"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="8">
        <location>
            <position position="357"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="356"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="360"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="379"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="10">
        <location>
            <position position="442"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR634016-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR634016-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR634016-4"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU364040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF01433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF11838"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF17900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="OBZ82812.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="926" mass="104045" checksum="33998EA6B8AF540D" modified="2016-11-30" version="1">MCTSSVENPDRQVLPTNVKPTHYDLTLQPNLKTFVFYGQVKINLNVNQDTKTIVLNTRDIKIYSAHLSSEGLKTVSKQKATEITYDKEKDLATMTFAEAVLANTKAVLEIAFEGELNNAMAGFYRSSYKDANGETQYLATTQFESTDARRAFPCWDEPSLKATFDVTLVVPSELVALSNMDVISEKPYHDTGKLTGKTEGKTEGKTEGKTEGKTEGKTEGKTETTSQSLKEVKYSTTPLMSTYLVAFCVGPFEYIEAFTSGEYNGRPIRSRVYALPGSVEQGRHALNVCTAALEYFAKVFGEPYPLPKVDMVAIPDFDAGAMENWGLITYRTVALLFDEKSSSISFKKSTAYTVCHELAHQWFGNLVTMEWWDHLWLNEGFATWVGWLAVDNIFPDWDVWTSFVNEDMPRALSLDALRSSHPIEVTVNDPAEIHQIFDAISYYKGASVIRMLSSWLGVDTFLAGVRRYLRRHKLANASTNDLWAALSEEANVDVSKFMTLWTKRVGYPVLTVKKASENTVNVTQSRYLSTGDLSEQEDTTVWWVPLGVLVPGKVEAYTLTEKTQDFDVPADGLFKLNAGQTSVYRVNYPIETIRVLGEEVKKGKSGLLSNAADRVGLVADAGNLCVSGEQTTVAFLELAQAFVNEEDYFVWSQLSTHLSKILSVWYEQPEEIQDGLKALRRSLFAPVAHKLGWEFAETDDYLTNILRVLAITNAGRSNDRQTVEEAKKRFWQFVEGNTEVVHPNLRGPVFSIVLGAAENEAEEEKLWEQILKIYHDESLPVDQRLIALSSLGGAKSKSLVQRYLEMSMDEKQVRGQDSIYVFAALSANSDARDLFWKFFTENFDVLHSKFAQSFGLFNSAVRSAVGGFVSSERIKEIEDFFADKNTKEYARSLQQALEGCKVNSKWIERDHKLVASWVQENAKKFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N1A1</accession>
    <name>A0A1C7N1A1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Protein SKT5</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">SKT5_2</name>
        <name evidence="3" type="ORF">A0J61_09037</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000759">
        <property type="protein sequence ID" value="OBZ82915.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N1A1"/>
    <dbReference type="STRING" id="101091.A0A1C7N1A1"/>
    <dbReference type="InParanoid" id="A0A1C7N1A1"/>
    <dbReference type="OrthoDB" id="272077at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051726">
        <property type="entry name" value="Chitin_Synth_Reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006597">
        <property type="entry name" value="Sel1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46430:SF1">
        <property type="entry name" value="CHITIN SYNTHASE REGULATOR SKT5-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46430">
        <property type="entry name" value="PROTEIN SKT5-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08238">
        <property type="entry name" value="Sel1"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SMART" id="SM00671">
        <property type="entry name" value="SEL1"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81901">
        <property type="entry name" value="HCP-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="217"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="277"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="231"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="279"/>
            <end position="291"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ82915.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="692" mass="78556" checksum="490FA59781E7F22F" modified="2016-11-30" version="1">MDLIHTTSDADVQSEQRDFSFKPLDSMDSFESYQDEPTLRPARHTLLLVEDEDMSSEEEEEGSTLSSDKFFLLNKDKVDSIRKTRPLPQLPSRNKEGAGAFVDVKKPNRIAAQELFQMLSKHQSELEENGGDTSDEDEEYGGVFALKTQMPSPKLSAKEQLHLYYHEHSYKLMTPVEEVDEEDQLFNEVSSTDSENEDDHDASVIKRLSDISLEDATSGRTTPLLTDDSPRTSLEYAQQRPSLERPSSYSPLQAMADSSPQHDKSLLSDVQKLAEMSKSMETPTVSPSLLPSQAAHLSPSSSVKLPEMPTPSSSNSSIASISLTHDIKTYRRMAEKTHDRHIQFTFATYLIQLVNSNDEQLKKPAREKLQVEAEYWIEKLAKSDYAKALYIKGKWHHDLRSSKIFVGSQYKKVNHAKAFKCFQKAAKYGSIDAHYELAEYWMVRKEYKKSISSYRYAASKNHVQSLYKLANVLLRGLLNQSKDIQQGIIYLRRAADVNKPESAQSAFDLACIFSNDLESVDLERTPEIDVFMTAKNYAAAVDYFKKADQYGLVNATYRLGHIYEMGLNYVAPDPWVAFKYFSRAAERRHEGAMMNLSRIYRTGIVDCLRPRPDLAYSWCLRVANNGNEVAEYTLGLYYERGVGVNIDLLQATEWFRKSASKGYQPANEKLSILMPNTQSKGYNQVQNTGLVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N1V0</accession>
    <name>A0A1C7N1V0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Putative histone-binding protein Caf1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">Caf1</name>
        <name evidence="8" type="ORF">A0J61_08856</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000723">
        <property type="protein sequence ID" value="OBZ83093.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N1V0"/>
    <dbReference type="FunCoup" id="A0A1C7N1V0">
        <property type="interactions" value="919"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N1V0"/>
    <dbReference type="InParanoid" id="A0A1C7N1V0"/>
    <dbReference type="OrthoDB" id="427795at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006325">
        <property type="term" value="P:chromatin organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022052">
        <property type="entry name" value="Histone-bd_RBBP4-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050459">
        <property type="entry name" value="WD_repeat_RBAP46/RBAP48/MSI1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22850">
        <property type="entry name" value="WD40 REPEAT FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12265">
        <property type="entry name" value="CAF1C_H4-bd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 6" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="Histone-binding protein RBBP4-like N-terminal" evidence="7">
        <location>
            <begin position="16"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="172"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="224"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="267"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="311"/>
            <end position="345"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF12265"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OBZ83093.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="422" mass="48356" checksum="4B136915C7BA1EDD" modified="2016-11-30" version="1">MELEHQQSQEEQLIQEEYTLWKKNAPFLYDTIITHGLEWPSLTCQWFPDVESRPDKNYKTQRLLLGTHTNDEEPNYLLIASVQLPSNTHDIDLRKYEETTNEIGGYGAFNDAHIQVQQKIVHEGEVNRARYQYENPNVIATKSRSGEVYVFDRTTHGSIPRENEPFHPALCLKGHHAEGYGLAWNPHKAKSTHILSSGSDRLICHWDIAAASKEHRHLDPLRTYRGHEAGVMDIAWHMKHDTIFASCGDDQRLMIWDTRDHDPIQSVQAHTSEINCVGFSPGNEWILATGSSDKTAALWDLRNLNHRLHTFQSHKEEVVQLAWSPHHDAILATASNDRRICVWDLARIGDELSTEEAQYGPPELMFIHGGHSGIISDFGWNPAVPWMMASTAEDNQVQTWQIASTIYGQEEQEESDKMEFTH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N1V7</accession>
    <name>A0A1C7N1V7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Protein SEY1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">SEY1_1</name>
        <name evidence="8" type="synonym">SEY1</name>
        <name evidence="12" type="ORF">A0J61_08924</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Endoplasmic reticulum membrane</location>
            <topology evidence="8">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <text evidence="8">Enriched in the cortical ER. Concentrated in punctae along the ER tubules.</text>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the TRAFAC class dynamin-like GTPase superfamily. GB1/RHD3 GTPase family. RHD3 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000737">
        <property type="protein sequence ID" value="OBZ83027.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N1V7"/>
    <dbReference type="FunCoup" id="A0A1C7N1V7">
        <property type="interactions" value="187"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N1V7"/>
    <dbReference type="InParanoid" id="A0A1C7N1V7"/>
    <dbReference type="OrthoDB" id="1597724at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016320">
        <property type="term" value="P:endoplasmic reticulum membrane fusion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01851">
        <property type="entry name" value="GBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000727">
        <property type="entry name" value="Protein SEY1 homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03109">
        <property type="entry name" value="Sey1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030386">
        <property type="entry name" value="G_GB1_RHD3_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008803">
        <property type="entry name" value="RHD3/Sey1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046758">
        <property type="entry name" value="Sey1/RHD3-like_3HB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45923">
        <property type="entry name" value="PROTEIN SEY1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45923:SF2">
        <property type="entry name" value="PROTEIN SEY1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05879">
        <property type="entry name" value="RHD3_GTPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20428">
        <property type="entry name" value="Sey1_3HB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51715">
        <property type="entry name" value="G_GB1_RHD3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 8" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="6 8" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="3 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7 8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 8 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="topological domain" description="Cytoplasmic" evidence="8">
        <location>
            <begin position="1"/>
            <end position="672"/>
        </location>
    </feature>
    <feature type="topological domain" description="Lumenal" evidence="8">
        <location>
            <begin position="694"/>
            <end position="696"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="697"/>
            <end position="715"/>
        </location>
    </feature>
    <feature type="topological domain" description="Cytoplasmic" evidence="8">
        <location>
            <begin position="718"/>
            <end position="763"/>
        </location>
    </feature>
    <feature type="domain" description="GB1/RHD3-type G" evidence="11">
        <location>
            <begin position="50"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="60"/>
            <end position="67"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51715"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="OBZ83027.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="763" mass="88758" checksum="7DB62BA50CADBB67" modified="2016-11-30" version="1">MNSDASATKPTENGNNNTQPNSQIQVINEEKKFNQNLAKHFQEWGLLDVGLNYNVVAVFGSQSTGKSTLLNRLFGTDFVEMKENSRKQTTKGIWLSRARDMRVLVMDVEGTDGRERGEDQDFERKSALFSMATSEVIIINLWEHQVGLYQGANMGLLKTVFEVNLQLFQNQKKETRIKEKTLLFIVIRDLVGTTPLDNLASVLRSDFEKNWESLSKPEDLKDCKITDYFDFMFIGLPHKILQPDQFNNEVINLRKRFNDPSNPDYVFRPEYHKRIPADGYELYASSIWDKILTNKDLDLPTQQELLAQYRCDEIANNAFDIFREQLAPLKSPVLEKNQILPDLGEKMTALREQALQMFDKSSSRYNQTVYQKKRLDMLNKLNSQLSIYFTGQLGSLRKKAVQTFDTELDQKLKAIDYNFTQIVHGCTEHAKNIFLNGAKAILLSDTDWSFHSEEERMKEDLEAISSRARTEEYKKMHKVIEKQIESDLSDSISIELNRPDNHMWHKIIQVYKSITTHAESMLSHKAKSFDSSPEDLKQSLEEMKIRAWLLLRKKVDEELTDNLLLLKLRNQFEDKFRYDDKGVPKVWKPEDDIDIYFRKARDETLDVIKLYAQVDLSQDKDFNIDATDDFDFSQSLRVLSEAKQIDIANRFKRESDAFYLEAKRSVVSTTAKVPTWVIGLMIFLGWNEFMAIVKNPLYLVIFSFCIMIGYVLYALNLWGPAERIFNTVVNEGTRMVKRQLVEVVNTTEHQPQYEMTTLKDKKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N2A6</accession>
    <name>A0A1C7N2A6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Proton myo-inositol cotransporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">SLC2A13</name>
        <name evidence="12" type="ORF">A0J61_08779</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000710">
        <property type="protein sequence ID" value="OBZ83167.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N2A6"/>
    <dbReference type="FunCoup" id="A0A1C7N2A6">
        <property type="interactions" value="203"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N2A6"/>
    <dbReference type="InParanoid" id="A0A1C7N2A6"/>
    <dbReference type="OrthoDB" id="508119at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015798">
        <property type="term" value="P:myo-inositol transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015791">
        <property type="term" value="P:polyol transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050814">
        <property type="entry name" value="Myo-inositol_Transporter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016201">
        <property type="entry name" value="PSI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00879">
        <property type="entry name" value="SP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48020">
        <property type="entry name" value="PROTON MYO-INOSITOL COTRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48020:SF12">
        <property type="entry name" value="PROTON MYO-INOSITOL COTRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00171">
        <property type="entry name" value="SUGRTRNSPORT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00423">
        <property type="entry name" value="PSI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00217">
        <property type="entry name" value="SUGAR_TRANSPORT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="6 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 8" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="47"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="89"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="116"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="142"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="175"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="206"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="286"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="329"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="356"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="442"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="477"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="510"/>
            <end position="528"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="11">
        <location>
            <begin position="51"/>
            <end position="532"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="OBZ83167.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="546" mass="59496" checksum="E47294994EFB3267" modified="2016-11-30" version="1">MSLTDIKKVNSQERQENDKVLDPHDEVFEPHEEISDESEMTGKASSFVYTLVICVCIGGFLFGYDTGVISGALTLLQKDFAMTSVQKELVVGGTTFGAIFGGFFSGILTDRFGRKILVIVSSLIFIAGALILALAPNYGVLLFGRIVVGLGVGIASMIVPVYVSELSPKYMRGRLNTLNTLVLTFGQVVAYVMNIAFASVPNGWRYMFGIAGIPALFQFIIMPFLPESPRRLVAIGKMDEAKRAIRKVYGNSVTDVFIEREVQMIDADIHTCRSGSFRDFAHRDNLMPLIIACILQAAQQLSGFNAAMYYAATILQMAGFKSTEGSTSVAIIVSGTNMVFTAIAISVIDKVGRRKMLLFTMITMIAGLIALGATFAAQQGFVVQQALCGGYSANCARCVLDERCGWSVSQDVCVFRENNLSDILATSNGCPPQAHDQPITGVLLTFLIVYVGSYALGLGYIPWLAQSEMFPMSIRGKANGVATAVNWICNLIVSTTFLSMTEAMTTAGTFWFYAGVSLVFWVLLIRLMPETSGKSLEEIHEYFLKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N2D1</accession>
    <name>A0A1C7N2D1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Defective in cullin neddylation protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">Dcun1d4</name>
        <name evidence="3" type="ORF">A0J61_10436</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Neddylation of cullins play an essential role in the regulation of SCF-type complexes activity.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001172">
        <property type="protein sequence ID" value="OBZ81514.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N2D1"/>
    <dbReference type="STRING" id="101091.A0A1C7N2D1"/>
    <dbReference type="InParanoid" id="A0A1C7N2D1"/>
    <dbReference type="OrthoDB" id="27198at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000151">
        <property type="term" value="C:ubiquitin ligase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097602">
        <property type="term" value="F:cullin family protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031624">
        <property type="term" value="F:ubiquitin conjugating enzyme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032182">
        <property type="term" value="F:ubiquitin-like protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045116">
        <property type="term" value="P:protein neddylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.238.200:FF:000003">
        <property type="entry name" value="DCN1-like protein 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.200">
        <property type="entry name" value="Cullin, PONY binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014764">
        <property type="entry name" value="DCN-prot"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042460">
        <property type="entry name" value="DCN1-like_PONY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005176">
        <property type="entry name" value="PONY_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12281:SF12">
        <property type="entry name" value="DEFECTIVE IN CULLIN NEDDYLATION PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12281">
        <property type="entry name" value="RP42 RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03556">
        <property type="entry name" value="Cullin_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51229">
        <property type="entry name" value="DCUN1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DCUN1" evidence="2">
        <location>
            <begin position="1"/>
            <end position="170"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU410713"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ81514.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="173" mass="20182" checksum="EDBF5DCFADF0DDD6" modified="2016-11-30" version="1">MTPDGCQQFYTDLGVNLESTLPLIVGYKMKSNQMGYITRQEFMQTMSSLDVSTSDEFKKTLCHWEETVLNEPSEFKQLYLFTFQYVKSTTQKSMDVETAIALWSILLEPKYPIIKSFIQFIQETKPVKVINKDQWSSLLDFCKAVPQDLSTYDCTSSWPVLFDDFVEWKNKTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N2J2</accession>
    <name>A0A1C7N2J2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_10377</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001142">
        <property type="protein sequence ID" value="OBZ81574.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N2J2"/>
    <dbReference type="STRING" id="101091.A0A1C7N2J2"/>
    <dbReference type="InParanoid" id="A0A1C7N2J2"/>
    <dbReference type="OrthoDB" id="2290219at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004190">
        <property type="term" value="F:aspartic-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00303">
        <property type="entry name" value="retropepsin_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.70.10">
        <property type="entry name" value="Acid Proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001969">
        <property type="entry name" value="Aspartic_peptidase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021109">
        <property type="entry name" value="Peptidase_aspartic_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13975">
        <property type="entry name" value="gag-asp_proteas"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50630">
        <property type="entry name" value="Acid proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00141">
        <property type="entry name" value="ASP_PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0064">Aspartyl protease</keyword>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0645">Protease</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022750"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ81574.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="244" mass="27044" checksum="85822436961401EE" modified="2016-11-30" version="1">MTRTKVVDDPMELDALDSRRGRFGHGEAGRAGNGFSRGDFGSRRFGNAGASSVEDQEVQLQDKHDDNFLENKNLIDLDPYSSTELDNELFPVLAPINCTKNMPTELLPIVYSNQNDDEIKYLSELNAIATSLPLYSGSFGNKAISILIDSGASENYVSPNIIENITADQLIPVHDRQVETAGGTVAQIEYKVQMEVDLNGFKDTVMAYVFPTKFDLILGRAWLKQAKPMPNWATDTWYLKNGSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N2U1</accession>
    <name>A0A1C7N2U1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_08538</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000667">
        <property type="protein sequence ID" value="OBZ83410.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N2U1"/>
    <dbReference type="InParanoid" id="A0A1C7N2U1"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ83410.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="101" mass="11506" checksum="7CC1F75A878ECD1D" modified="2016-11-30" version="1">MLQCKISIHPISVEHATLEQTDNSKHVPDSKEPKCIWYEDYEQKGDRSSHSYPSCLSLSLSQPPVMRNILYVAVFTFFVAYVSAKENPCPPGHKHDFHGKC</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N329</accession>
    <name>A0A1C7N329_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_08904</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000732">
        <property type="protein sequence ID" value="OBZ83046.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N329"/>
    <dbReference type="InParanoid" id="A0A1C7N329"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="42"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ83046.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="62" mass="7155" checksum="D7E655C22506DC29" modified="2016-11-30" version="1">MEVLFTRMNTMMSSQVTTIEKLCTMISSFGFDLILFTVTVIIQQIDNASLGVEWEIRIHKDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N3B2</accession>
    <name>A0A1C7N3B2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Splicing factor U2AF subunit</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">U2 snRNP auxiliary factor large subunit</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="primary">U2af50</name>
        <name evidence="11" type="ORF">A0J61_08811</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Necessary for the splicing of pre-mRNA.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 8">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the splicing factor SR family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000715">
        <property type="protein sequence ID" value="OBZ83139.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N3B2"/>
    <dbReference type="FunCoup" id="A0A1C7N3B2">
        <property type="interactions" value="660"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N3B2"/>
    <dbReference type="InParanoid" id="A0A1C7N3B2"/>
    <dbReference type="OrthoDB" id="10266058at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008380">
        <property type="term" value="P:RNA splicing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd12230">
        <property type="entry name" value="RRM1_U2AF65"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd12231">
        <property type="entry name" value="RRM2_U2AF65"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd12232">
        <property type="entry name" value="RRM3_U2AF65"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.330:FF:000097">
        <property type="entry name" value="U2 snRNP auxiliary factor large subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.330:FF:000676">
        <property type="entry name" value="U2 snRNP auxiliary factor large subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006529">
        <property type="entry name" value="U2AF_lg"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01642">
        <property type="entry name" value="U2AF_lg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23139">
        <property type="entry name" value="RNA-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 8" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="5 8" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="6 8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 7 8" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="10">
        <location>
            <begin position="233"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="10">
        <location>
            <begin position="342"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="10">
        <location>
            <begin position="456"/>
            <end position="546"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="11"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="9">
        <location>
            <begin position="80"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="9">
        <location>
            <begin position="107"/>
            <end position="128"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU364135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="OBZ83139.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="554" mass="62583" checksum="8AD9F4C95E0A2D03" modified="2016-11-30" version="1">MSYGWNRDPNVPSQQSAADLANSFLNSVGQELQGSNETPYGMEAPPPGRYSEDAYNDYSRNDSNRDRRHSRDRYHDRSRETRRRRSRERRERSPRHRSSRGDDRDYRRRRRSPSPRRSSRRRSPSSHRRRDDENIIPLSKRERKLHNWDMAPAGMEGMTAEQVKSTGLFPLPGQVVGTRTPQSFQPPPVNGSHPTTLYHYNDHATMHDGSRVRITQGAAGPVALNATLARQAKRLYVGQIPFGIDEKGMADFFNATMEQLKLADTTPVIAVQINHDKNYAFVEFETPEQATMAMAVDGIMFQGQQLKIRRPKDYQPPVDGDYGEHPPQLPGLVSTNVPDTPNKIFIGGLPVYLNDDQVVELLKSFGELRAFNLVKDPLTGANKGFAFCEYADPSRTDLACQGLNNMELGDRKLVVQRASVGAKHGALPTEYATGQVPLTVADYLPISSAKEEEATRVLQLMNMVTPDELEDDEEYQDIWEDIAEECSKFGTIVDMKIPRPSKDGPVPGCGLIFVRYETKEMTLEALRALAGRKFADRTVITTFVDEENYLTDNF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N3T6</accession>
    <name>A0A1C7N3T6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Chaperone protein DnaJ</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">dnaJ_0</name>
        <name evidence="3" type="ORF">A0J61_08219</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000613">
        <property type="protein sequence ID" value="OBZ83731.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N3T6"/>
    <dbReference type="STRING" id="101091.A0A1C7N3T6"/>
    <dbReference type="InParanoid" id="A0A1C7N3T6"/>
    <dbReference type="OrthoDB" id="445556at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051938">
        <property type="entry name" value="Apopto_cytoskel_mod"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44145">
        <property type="entry name" value="DNAJ HOMOLOG SUBFAMILY A MEMBER 3, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44145:SF3">
        <property type="entry name" value="DNAJ HOMOLOG SUBFAMILY A MEMBER 3, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00625">
        <property type="entry name" value="JDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0143">Chaperone</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="J" evidence="2">
        <location>
            <begin position="16"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ83731.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="72" mass="8406" checksum="955D0A1BC6C4FA71" modified="2016-11-30" version="1" fragment="single">MLLKRGFSSSSVSRRNFYDVLQLRENADRKSIKANYYKLSKKYHPDLNPNNKEAHKLFLEINEAYAVLGNEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N4N9</accession>
    <name>A0A1C7N4N9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 14">Dol-P-Man:Man(5)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase</fullName>
            <ecNumber evidence="3 14">2.4.1.258</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="14">Dol-P-Man-dependent alpha(1-3)-mannosyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="15" type="primary">ALG3</name>
        <name evidence="15" type="ORF">A0J61_07958</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11 14">Dol-P-Man:Man(5)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase that operates in the biosynthetic pathway of dolichol-linked oligosaccharides, the glycan precursors employed in protein asparagine (N)-glycosylation. The assembly of dolichol-linked oligosaccharides begins on the cytosolic side of the endoplasmic reticulum membrane and finishes in its lumen. The sequential addition of sugars to dolichol pyrophosphate produces dolichol-linked oligosaccharides containing fourteen sugars, including two GlcNAcs, nine mannoses and three glucoses. Once assembled, the oligosaccharide is transferred from the lipid to nascent proteins by oligosaccharyltransferases. In the lumen of the endoplasmic reticulum, adds the first dolichyl beta-D-mannosyl phosphate derived mannose in an alpha-1,3 linkage to Man(5)GlcNAc(2)-PP-dolichol to produce Man(6)GlcNAc(2)-PP-dolichol.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12 14">
            <text>an alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;6)]-beta-D-Man-(1-&gt;4)-beta-D-GlcNAc-(1-&gt;4)-alpha-D-GlcNAc-diphospho-di-trans,poly-cis-dolichol + a di-trans,poly-cis-dolichyl beta-D-mannosyl phosphate = an alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;3)-alpha-D-Man-(1-&gt;6)]-beta-D-Man-(1-&gt;4)-beta-D-GlcNAc-(1-&gt;4)-alpha-D-GlcNAc-diphospho-di-trans,poly-cis-dolichol + a di-trans,poly-cis-dolichyl phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:29527"/>
            <dbReference type="Rhea" id="RHEA-COMP:19498"/>
            <dbReference type="Rhea" id="RHEA-COMP:19501"/>
            <dbReference type="Rhea" id="RHEA-COMP:19516"/>
            <dbReference type="Rhea" id="RHEA-COMP:19517"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57683"/>
            <dbReference type="ChEBI" id="CHEBI:58211"/>
            <dbReference type="ChEBI" id="CHEBI:132515"/>
            <dbReference type="ChEBI" id="CHEBI:132516"/>
            <dbReference type="EC" id="2.4.1.258"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="12 14">
            <dbReference type="Rhea" id="RHEA:29528"/>
        </physiologicalReaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 14">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 14">Endoplasmic reticulum membrane</location>
            <topology evidence="1 14">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="13">Belongs to the glycosyltransferase ALG3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.258" evidence="3 14"/>
    <dbReference type="EMBL" id="LUGH01000572">
        <property type="protein sequence ID" value="OBZ83988.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N4N9"/>
    <dbReference type="FunCoup" id="A0A1C7N4N9">
        <property type="interactions" value="536"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N4N9"/>
    <dbReference type="InParanoid" id="A0A1C7N4N9"/>
    <dbReference type="OrthoDB" id="20028at2759"/>
    <dbReference type="UniPathway" id="UPA00378"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052925">
        <property type="term" value="F:dol-P-Man:Man(5)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006488">
        <property type="term" value="P:dolichol-linked oligosaccharide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018279">
        <property type="term" value="P:protein N-linked glycosylation via asparagine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007873">
        <property type="entry name" value="Glycosyltransferase_ALG3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12646:SF0">
        <property type="entry name" value="DOL-P-MAN:MAN(5)GLCNAC(2)-PP-DOL ALPHA-1,3-MANNOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12646">
        <property type="entry name" value="NOT56 - RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05208">
        <property type="entry name" value="ALG3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 14" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="5 14 15" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="10 14" id="KW-0472">Membrane</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 14 15" id="KW-0808">Transferase</keyword>
    <keyword evidence="7 14" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 14" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="38"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="168"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="193"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="228"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="285"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="328"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="405"/>
            <end position="426"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00015561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00044743"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00049506"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00093457"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU364047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="OBZ83988.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="434" mass="50424" checksum="54244A55EF2D3EA0" modified="2016-11-30" version="1">MPTVKRQKARKLNKESRKVYSFQDITRIPLELLCNPDYFWHLAAIFLLGEFILSTLIIQKVAYTEIDWIAYMQEVEGFLHGERDYTKLKGDTGPLVYPAGFVYFYSALFKITHQGQNIRLAQYIFEAIYLISQGLTCAIYRQSKRVPPYVILLLGCSKRFHSIFLLRCFNDPVAMVFMLGCILAMTYRKWTLSAILFSLALSIKMNVLLFFPAYGILLWMAIGAYRTLGQLSLMAVIQYGLGYPFLKTYPQSYLSKAFEFGRVFDYTWTVNWRMMTEETFVSNSFAIQLMAGHAFTLLMFIVCIWCPPKGGLFHVFKQGFSFQQRLNLSNDDIISMMFTSNFIGILFARSLHYQFYSWYFQTLPYLLWQSAWQTTRQGYQATSRILIFTTIEACWLTFPSTVKSSWTLVACHIMLLLGIFGNSPAVDDLSWKKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N5J9</accession>
    <name>A0A1C7N5J9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Tethering factor for nuclear proteasome STS1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">sts1_1</name>
        <name evidence="5" type="ORF">A0J61_07526</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Involved in ubiquitin-mediated protein degradation. Regulatory factor in the ubiquitin/proteasome pathway that controls the turnover of proteasome substrates. Targets proteasomes to the nucleus and facilitates the degradation of nuclear proteins.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Binds the proteasome.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="3">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the cut8/STS1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000512">
        <property type="protein sequence ID" value="OBZ84425.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N5J9"/>
    <dbReference type="STRING" id="101091.A0A1C7N5J9"/>
    <dbReference type="InParanoid" id="A0A1C7N5J9"/>
    <dbReference type="OrthoDB" id="10061064at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031965">
        <property type="term" value="C:nuclear membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000502">
        <property type="term" value="C:proteasome complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070628">
        <property type="term" value="F:proteasome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071630">
        <property type="term" value="P:nuclear protein quality control by the ubiquitin-proteasome system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031144">
        <property type="term" value="P:proteasome localization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.1590">
        <property type="entry name" value="Tethering factor for nuclear proteasome Cut8/Sts1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013868">
        <property type="entry name" value="Cut8/Sts1_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038422">
        <property type="entry name" value="Cut8/Sts1_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28032">
        <property type="entry name" value="FI02826P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28032:SF1">
        <property type="entry name" value="FI02826P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08559">
        <property type="entry name" value="Cut8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-0647">Proteasome</keyword>
    <keyword evidence="3" id="KW-0653">Protein transport</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="48"/>
            <end position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU368013"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OBZ84425.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="290" mass="33698" checksum="65A498954BF6F74C" modified="2016-11-30" version="1">MTYLQVNQSNDMYRGRKRRPSEDEEMTETTTSRPMLTRKSKSPEQKRQRTHLQKRSTRGALLETLDKEALVNIIDSLLKTQPIVQRDIMNYIPAPTIHSAIGVLSDLEKKFIQSFPFKKHGPGRDDYTFSRVQEALTDLVDTITQYANHFTSSQIFPSNSFTFLNHVTHMAHRLPDWDNEENNQLKKELYRDLNLFWKTAIQATAAKLTADQYSPDSVREWAKQLAQHHSYTDNNYFTESVVEFSRQLGYWMDSNHQPTFPSLSSSTHHHCLTPLENTLIPSHSVVGDRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N6N3</accession>
    <name>A0A1C7N6N3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_07687</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000534">
        <property type="protein sequence ID" value="OBZ84259.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N6N3"/>
    <dbReference type="InParanoid" id="A0A1C7N6N3"/>
    <dbReference type="OrthoDB" id="2357290at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008889510" evidence="1">
        <location>
            <begin position="20"/>
            <end position="166"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ84259.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="166" mass="19124" checksum="5A79AE3069469891" modified="2016-11-30" version="1">MLLLKPFVVLYTVILAVIAQESLISIRTPSLNQIVVPGQSVDIEYTVNAQSSSTLIPNYPPSMDLYLRWKKNQEPHLELKAITGLSTQSIASGTQPKTYHRRWKLPHCQFFKRYSPPEWSFTVEFEMRYSEDDARRISGPRQTTVVIPIQINTTLSDHHHHNGCYQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N6U6</accession>
    <name>A0A1C7N6U6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_07138</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000466">
        <property type="protein sequence ID" value="OBZ84812.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N6U6"/>
    <dbReference type="InParanoid" id="A0A1C7N6U6"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ84812.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="162" mass="19001" checksum="CBBF7B64FFC37D5D" modified="2016-11-30" version="1">MIESYKTVCSKEIFVKNQIPFIELPRLLNQYVKKQANKKWMLTSKRYMEQNLVPFHPLFFTQGKPIQQAASLVLRVFVEESNCQRVKAFKSRLPDKPNNLAHQLLNGYIDRLSKQKEFSAEEFDRKELKKDMLNIYEKILAGAIRDANNNLKAKAIKLAKRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N739</accession>
    <name>A0A1C7N739_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Condensin complex subunit 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">cnd1</name>
        <name evidence="14" type="ORF">A0J61_07544</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Chromosome</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the CND1 (condensin subunit 1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000514">
        <property type="protein sequence ID" value="OBZ84409.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N739"/>
    <dbReference type="FunCoup" id="A0A1C7N739">
        <property type="interactions" value="330"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N739"/>
    <dbReference type="InParanoid" id="A0A1C7N739"/>
    <dbReference type="OrthoDB" id="436262at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000796">
        <property type="term" value="C:condensin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000791">
        <property type="term" value="C:euchromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000776">
        <property type="term" value="C:kinetochore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140602">
        <property type="term" value="C:nucleolar peripheral inclusion body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003682">
        <property type="term" value="F:chromatin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003690">
        <property type="term" value="F:double-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042393">
        <property type="term" value="F:histone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043007">
        <property type="term" value="P:maintenance of rDNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010032">
        <property type="term" value="P:meiotic chromosome condensation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051307">
        <property type="term" value="P:meiotic chromosome separation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007076">
        <property type="term" value="P:mitotic chromosome condensation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:1903342">
        <property type="term" value="P:negative regulation of meiotic DNA double-strand break formation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044804">
        <property type="term" value="P:nucleophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070550">
        <property type="term" value="P:rDNA chromatin condensation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030466">
        <property type="term" value="P:silent mating-type cassette heterochromatin formation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007130">
        <property type="term" value="P:synaptonemal complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070058">
        <property type="term" value="P:tRNA gene clustering"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026971">
        <property type="entry name" value="CND1/NCAPD3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032682">
        <property type="entry name" value="Cnd1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007673">
        <property type="entry name" value="Condensin_cplx_su1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024324">
        <property type="entry name" value="Condensin_cplx_su1_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14222">
        <property type="entry name" value="CONDENSIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14222:SF2">
        <property type="entry name" value="CONDENSIN COMPLEX SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12717">
        <property type="entry name" value="Cnd1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12922">
        <property type="entry name" value="Cnd1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF017127">
        <property type="entry name" value="Condensin_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 10" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="5 10" id="KW-0132">Cell division</keyword>
    <keyword evidence="4" id="KW-0158">Chromosome</keyword>
    <keyword evidence="7 10" id="KW-0226">DNA condensation</keyword>
    <keyword evidence="6 10" id="KW-0498">Mitosis</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Condensin complex subunit 1 N-terminal" evidence="13">
        <location>
            <begin position="78"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="domain" description="Condensin complex subunit 1 C-terminal" evidence="12">
        <location>
            <begin position="976"/>
            <end position="1140"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="474"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="866"/>
            <end position="892"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1195"/>
            <end position="1242"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="881"/>
            <end position="892"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="1195"/>
            <end position="1209"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="11">
        <location>
            <begin position="1223"/>
            <end position="1234"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009606"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023067"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRNR" id="PIRNR017127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF12717"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF12922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="OBZ84409.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="1242" mass="143272" checksum="9A88C03A96EC3550" modified="2016-11-30" version="1">MRDQFVLSEEVLKLQENDQLNYYIPNETEIRGKSDQDLARFLNEMTDHVQVSSDNITDPLVFDKLRSFLKYFASVKPRILSRLFDIISSGFQAEIKATADDVENNEKESFSNHRLHLEMYSFLIYWFLLQAEDNATTSTMMRKSKTNQASGNNDLKTFDWSSQKLKAFDLANWLLGLKLAKIWTLPPDRIAFINLFTKPAYQLFENPVYAKSSQIKERIFRVLSLCVKHYDHLSVAQTTIMQDLQYYEHSAETMAELLVYMIDKQNYTQLADEILREISNREFKDVSKEVKDSPNPKTFAAFLLKIAELSPKTILKNLTVLINQLDSESYLMRVTLIDILGYLIAELSKTIEENSNHMDQINGFFDILEERMLDPISYCRQKVLQVYLRLFTLKVKFPKRRHAATVLCVRHLQDKSSIVRKYAIRALTTLVSTHPYSMYGGELDLEEWTARLNTLKQETENVISEDDVRALGVEQEDTDMAESDHPEERRPKKTVVSPEKLQQLVLMRTFHTDAIQFIELIHNSMPTITQLLSSKSKAEVLESMDFLVTCYNYKVKLASDGIKKMLHLIWTKDTSDEGKGIKVKLLSCYENLYLEMDAKLSKRENVNRVAKNLIQLTFDTTLAELTSLEQLLSTLMEEGKILNDVVQKLWSVYGFTQGRIQKSLRRGAIVVLGMLAKTKTKIVSDKIDVMLKIGLGSLGKADLELARYTCLALQRLGGAKSKEKGRGVQEGTRFPLHHPIFARLKDILETPHESQEWFSMAEQAINTIYLLCKSPEVLCEELIRNKTHRVFNMPEDVSDSQLMPPPMESQLAEYDLSMSQQVLPFPQTPLYQKPLELAQLFFLVGHIALKELVHLEIVESAWKRKKQEKEKQSDQQQKAGEEEDELEQVGGTAEDDIGEAMIRIREREVLFGPHSLLGVYGPLLTEVCARNKVYTDRTLQINATLALTKFMCISSDFCEKKLRLLFTILEKSKDATIRSNIVIGLGDMAVCFNTLIDDNITFLYNRLSDSDTMVRKNAVMVLTHLILNGMVKVKGQISEMAKCLEDPDQRIADLARLFFTELASKDNAIYNNLPDIISNLTSTQPTRLEEESFRKIMKFIFSFDFTEKEKQAENIVDKLCQRFLTAQDERNWRDIAYCLSLLPFKTEKPFKKLLENWPTFQDKIHEESVHKSFMEIVQKGRLHKNQRPELKALVDELDQKMEKQRGPETEKDDEATPAPVQKKVTRATRSKLKRQRQDKEGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N746</accession>
    <name>A0A1C7N746_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Putative esterase C31F10.02</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">A0J61_07063</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the thioesterase PaaI family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000458">
        <property type="protein sequence ID" value="OBZ84887.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N746"/>
    <dbReference type="FunCoup" id="A0A1C7N746">
        <property type="interactions" value="76"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N746"/>
    <dbReference type="InParanoid" id="A0A1C7N746"/>
    <dbReference type="OrthoDB" id="46529at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047617">
        <property type="term" value="F:fatty acyl-CoA hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03443">
        <property type="entry name" value="PaaI_thioesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.129.10:FF:000033">
        <property type="entry name" value="acyl-coenzyme A thioesterase 13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.129.10">
        <property type="entry name" value="Hotdog Thioesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039298">
        <property type="entry name" value="ACOT13"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029069">
        <property type="entry name" value="HotDog_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003736">
        <property type="entry name" value="PAAI_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006683">
        <property type="entry name" value="Thioestr_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00369">
        <property type="entry name" value="unchar_dom_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21660:SF1">
        <property type="entry name" value="ACYL-COENZYME A THIOESTERASE 13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21660">
        <property type="entry name" value="THIOESTERASE SUPERFAMILY MEMBER-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03061">
        <property type="entry name" value="4HBT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54637">
        <property type="entry name" value="Thioesterase/thiol ester dehydrase-isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioesterase" evidence="3">
        <location>
            <begin position="63"/>
            <end position="136"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF03061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OBZ84887.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="159" mass="17044" checksum="FD538BDE74EF7818" modified="2016-11-30" version="1">MLPSTVLRTPELVQKVFKVSLKSFMTAGGYDSVVLPGLKILTTEEGRVRAELEVEKKHLNRLGSVHGGLLATIVDVAGSLAIASKGLYATGVSTDINISYISGVKQGEKINIDARVDKLGKTLAFTSVELSNKGRLVALGRHNKFVAQAYGHAENILKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N7B8</accession>
    <name>A0A1C7N7B8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Succinate dehydrogenase [ubiquinone] cytochrome b small subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">sdh4</name>
        <name evidence="14" type="ORF">A0J61_08730</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 12">Mitochondrion inner membrane</location>
            <topology evidence="1 12">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 12">Belongs to the CybS family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000700">
        <property type="protein sequence ID" value="OBZ83224.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N7B8"/>
    <dbReference type="FunCoup" id="A0A1C7N7B8">
        <property type="interactions" value="199"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N7B8"/>
    <dbReference type="InParanoid" id="A0A1C7N7B8"/>
    <dbReference type="OrthoDB" id="18577at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048039">
        <property type="term" value="F:ubiquinone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006121">
        <property type="term" value="P:mitochondrial electron transport, succinate to ubiquinone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd03496">
        <property type="entry name" value="SQR_TypeC_CybS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1300.10">
        <property type="entry name" value="Fumarate reductase/succinate dehydrogenase, transmembrane subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007992">
        <property type="entry name" value="CybS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034804">
        <property type="entry name" value="SQR/QFR_C/D"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13337">
        <property type="entry name" value="SUCCINATE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13337:SF2">
        <property type="entry name" value="SUCCINATE DEHYDROGENASE [UBIQUINONE] CYTOCHROME B SMALL SUBUNIT, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05328">
        <property type="entry name" value="CybS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81343">
        <property type="entry name" value="Fumarate reductase respiratory complex transmembrane subunits"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0408">Iron</keyword>
    <keyword evidence="9 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8 12" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5 12" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 12" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <keyword evidence="14" id="KW-0830">Ubiquinone</keyword>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="38"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="38"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="58"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="11">
        <location>
            <position position="132"/>
        </location>
        <ligand>
            <name>heme b</name>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
            <note>ligand shared with SDHC</note>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="144"/>
        </location>
        <ligand>
            <name>a ubiquinone</name>
            <dbReference type="ChEBI" id="CHEBI:16389"/>
            <note>ligand shared with IP/SDHB</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR607992-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR607992-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU364031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="OBZ83224.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="192" mass="21520" checksum="46121D1E8F22D414" modified="2016-11-30" version="1">MALRLFSRSVSSAHLYRSQVKLNPIVLRSYSAAASATNASLQNTTTKSDSATTTKTTTENEEKKTELEATEENAEKETIKKETKEHGYEFGAHHWNLERASAVALIPMFSTSLIYGAHPISDGLLGVVLPYHIYMGFDSCITDYIPKRVYPRLHRASNWANAVSTNLVMWGCYEFNTNDIGITEFMQRLFAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N7C1</accession>
    <name>A0A1C7N7C1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Signal recognition particle protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">ZK512.4</name>
        <name evidence="3" type="ORF">A0J61_07450</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000502">
        <property type="protein sequence ID" value="OBZ84509.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N7C1"/>
    <dbReference type="FunCoup" id="A0A1C7N7C1">
        <property type="interactions" value="4"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N7C1"/>
    <dbReference type="InParanoid" id="A0A1C7N7C1"/>
    <dbReference type="OrthoDB" id="360923at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005786">
        <property type="term" value="C:signal recognition particle, endoplasmic reticulum targeting"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008312">
        <property type="term" value="F:7S RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006614">
        <property type="term" value="P:SRP-dependent cotranslational protein targeting to membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.720.10">
        <property type="entry name" value="Signal recognition particle alu RNA binding heterodimer, srp9/1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009018">
        <property type="entry name" value="Signal_recog_particle_SRP9/14"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039914">
        <property type="entry name" value="SRP9-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039432">
        <property type="entry name" value="SRP9_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12834">
        <property type="entry name" value="SIGNAL RECOGNITION PARTICLE 9 KDA PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12834:SF12">
        <property type="entry name" value="SIGNAL RECOGNITION PARTICLE 9 KDA PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05486">
        <property type="entry name" value="SRP9-21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54762">
        <property type="entry name" value="Signal recognition particle alu RNA binding heterodimer, SRP9/14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SRP9" evidence="2">
        <location>
            <begin position="24"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="114"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="130"/>
            <end position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF05486"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ84509.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="139" mass="16084" checksum="16C63955F92CE485" modified="2016-11-30" version="1">MLLWQLEKEKQPLTYDWPALMYITNWDEFQKAAEDIYTASPEQTRYVHTFQRSDGDLVLKVTDDRTLVKYKTNQMTDLKKFIALNSELMLKMMNKEMAIDEDTVIPDAAPVSVAKNSVPEVKTASPKQTPKGKKGKKRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N8E5</accession>
    <name>A0A1C7N8E5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Cysteine-rich protein 2-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">CSRP2BP</name>
        <name evidence="8" type="ORF">A0J61_06602</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000406">
        <property type="protein sequence ID" value="OBZ85351.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N8E5"/>
    <dbReference type="STRING" id="101091.A0A1C7N8E5"/>
    <dbReference type="InParanoid" id="A0A1C7N8E5"/>
    <dbReference type="OrthoDB" id="4080456at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004402">
        <property type="term" value="F:histone acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04301">
        <property type="entry name" value="NAT_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.980.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019786">
        <property type="entry name" value="Zinc_finger_PHD-type_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001965">
        <property type="entry name" value="Znf_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019787">
        <property type="entry name" value="Znf_PHD-finger"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20916">
        <property type="entry name" value="CYSTEINE AND GLYCINE-RICH PROTEIN 2 BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20916:SF26">
        <property type="entry name" value="CYSTEINE-RICH PROTEIN 2-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13508">
        <property type="entry name" value="Acetyltransf_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00249">
        <property type="entry name" value="PHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01359">
        <property type="entry name" value="ZF_PHD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50016">
        <property type="entry name" value="ZF_PHD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="PHD-type" evidence="6">
        <location>
            <begin position="24"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="domain" description="N-acetyltransferase" evidence="7">
        <location>
            <begin position="527"/>
            <end position="666"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="186"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="192"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="223"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="240"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="263"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="280"/>
            <end position="290"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OBZ85351.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="666" mass="77215" checksum="A9BF593B3514A5CD" modified="2016-11-30" version="1">MKKKFPYNIEGLTWDAQHNTNMEDKYCYCGKGLKESQPMIRCDRCRQLFHRDCIECMKKPLLFGDTFGTFKCSVCNQGPETFERKPVSWITIVHLVIYNLMKHAMVEDAKKPKKDKREHYYFRWKEDVCAFIDDYWDYLMPDKTRSATWNNTIASVLSTHSNIFLSGLEKLHQSAWWTLRDFEPPKNEKKTKAAARPKPNIKRTLKRTTSQDAINNRPKRVKKDTESKPKQQEPQEDLLDLSSLSELSSAADSSDSENEIPTKKKNSQHQKKPVIVQTQEETEPLTEVEQQEQTVTITQPSVIREKSPIETAVIQPKLESTISESAKETYQLISTPNPSPVPLPSQSSTTLSSQQEWLLLQKLDHSSKKLPAVACRYKRKLAVRRLKRNLGIKLFDMDAQMIQWLRTTKHRLEPIVNNTIIQPASNQHIEQSPDDQQEAMLEKITFTPYACSFASRLYGSIRHRNTMTRDEPWLSSWNGRKLRPFIRRDFENKPKRMLLMGQIKACNGRPHAKGTPEPSGIVAGESIDYVYFQKEHLSQVNLLLSRSFWEGIDVSESLLFPEFSIVALYKRHVIGCAFMTPEAYITYFAVDPGWTNANIGQFMLYHLFQTAISKDITLHVSANNNAMILYQKFGFKPEEFIVNFYDKYLPADSVYSKNAFLLRLRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N8L3</accession>
    <name>A0A1C7N8L3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">Lysosomal dipeptide transporter MFSD1</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="16">Major facilitator superfamily domain-containing protein 1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="21" type="primary">Mfsd1</name>
        <name evidence="21" type="ORF">A0J61_06483</name>
    </gene>
    <organism evidence="21 22">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="21 22" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="21 22">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="17">Lysosomal dipeptide uniporter that selectively exports lysine, arginine or histidine-containing dipeptides with a net positive charge from the lysosome lumen into the cytosol. Could play a role in a specific type of protein O-glycosylation indirectly regulating macrophages migration and tissue invasion. Also essential for liver homeostasis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>L-alanyl-L-lysine(out) = L-alanyl-L-lysine(in)</text>
            <dbReference type="Rhea" id="RHEA:79415"/>
            <dbReference type="ChEBI" id="CHEBI:192470"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>L-alpha-aminoacyl-L-arginine(out) = L-alpha-aminoacyl-L-arginine(in)</text>
            <dbReference type="Rhea" id="RHEA:79367"/>
            <dbReference type="ChEBI" id="CHEBI:229968"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>L-alpha-aminoacyl-L-histidine(out) = L-alpha-aminoacyl-L-histidine(in)</text>
            <dbReference type="Rhea" id="RHEA:79375"/>
            <dbReference type="ChEBI" id="CHEBI:229967"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>L-alpha-aminoacyl-L-lysine(out) = L-alpha-aminoacyl-L-lysine(in)</text>
            <dbReference type="Rhea" id="RHEA:79383"/>
            <dbReference type="ChEBI" id="CHEBI:229966"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>L-arginyl-L-alpha-amino acid(out) = L-arginyl-L-alpha-amino acid(in)</text>
            <dbReference type="Rhea" id="RHEA:79371"/>
            <dbReference type="ChEBI" id="CHEBI:84315"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>L-arginyl-glycine(out) = L-arginyl-glycine(in)</text>
            <dbReference type="Rhea" id="RHEA:79391"/>
            <dbReference type="ChEBI" id="CHEBI:229955"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-aspartyl-L-lysine(out) = L-aspartyl-L-lysine(in)</text>
            <dbReference type="Rhea" id="RHEA:79411"/>
            <dbReference type="ChEBI" id="CHEBI:229953"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>L-histidyl-L-alpha-amino acid(out) = L-histidyl-L-alpha-amino acid(in)</text>
            <dbReference type="Rhea" id="RHEA:79379"/>
            <dbReference type="ChEBI" id="CHEBI:229964"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>L-histidyl-glycine(out) = L-histidyl-glycine(in)</text>
            <dbReference type="Rhea" id="RHEA:79395"/>
            <dbReference type="ChEBI" id="CHEBI:229957"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>L-lysyl-L-alanine(out) = L-lysyl-L-alanine(in)</text>
            <dbReference type="Rhea" id="RHEA:79399"/>
            <dbReference type="ChEBI" id="CHEBI:229954"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>L-lysyl-L-alpha-amino acid(out) = L-lysyl-L-alpha-amino acid(in)</text>
            <dbReference type="Rhea" id="RHEA:79387"/>
            <dbReference type="ChEBI" id="CHEBI:229965"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>L-lysyl-L-lysine(out) = L-lysyl-L-lysine(in)</text>
            <dbReference type="Rhea" id="RHEA:79403"/>
            <dbReference type="ChEBI" id="CHEBI:229956"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>L-lysyl-glycine(out) = L-lysyl-glycine(in)</text>
            <dbReference type="Rhea" id="RHEA:79407"/>
            <dbReference type="ChEBI" id="CHEBI:191202"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="18">Homodimer. Interacts with lysosomal protein GLMP (via lumenal domain); the interaction starts while both proteins are still in the endoplasmic reticulum and is required for stabilization of MFSD1 in lysosomes but has no direct effect on its targeting to lysosomes or transporter activity.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="21">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000393">
        <property type="protein sequence ID" value="OBZ85470.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N8L3"/>
    <dbReference type="STRING" id="101091.A0A1C7N8L3"/>
    <dbReference type="InParanoid" id="A0A1C7N8L3"/>
    <dbReference type="OrthoDB" id="424834at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052187">
        <property type="entry name" value="MFSD1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23512">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23512:SF12">
        <property type="entry name" value="TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_4G00260)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="19" id="KW-0472">Membrane</keyword>
    <keyword evidence="22" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="19" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="19" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="68"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="108"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="135"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="160"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="193"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="228"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="279"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="320"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="352"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="376"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="412"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="443"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="501"/>
            <end position="523"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="20">
        <location>
            <begin position="70"/>
            <end position="469"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00044876"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00044878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00044881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00044884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00044891"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00044893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00044898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00044899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00044900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00044903"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00044912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00044919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00044924"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00044985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00045018"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00045709"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00046376"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="EMBL" id="OBZ85470.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="524" mass="57213" checksum="652F8C3DB68FCC49" modified="2016-11-30" version="1">MNEQTPLLPKDTPPSCCSLKDDGKKPSCCSLKSACCSNKNDQKACSKLPPVNDDDYCFLAEQKWEYKCIALMCAIFLAVGSHFAAHTLGAMKNTIKEEFGISNSQYGVVQSSVAIVNTILPVIGGIFIDTFGTIPGALITTLLITSGNILVATSASFKSLYMMVIGRILYGIGSGTVVIVQETILSQWFKGRSLAAVVALMLTVSRLASFCAQATVVPIANWTGWYGYGLWFSASLCIFSMLVTFIYIGLLRTVSNPSIQCRKQLEVIKRKKTFSWSKLMYLPHSFWLVACMEFLLGGGWGCFLHINSEYVKMHFSYSDAHAAATASVAQILPVVLMPFLGVCVDRFGKRTWMMIGSGLMMLSSMLLLQFTPLPPLFGMLLFSISLSLGPVGLVSSVPVILPLSLVGTGMGLIKSGTNIGAALFDIATGLLQDADPNKGYNGVIQFFIVISVLAVFAGLVLHVLDQTMYHSVLSRSAREAHRSDENKLKTPKPLTRLRSNYVYGAIYFGLCCLSWVLFFRFIMA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N8Z1</accession>
    <name>A0A1C7N8Z1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">O-methylsterigmatocystin oxidoreductase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">A0J61_06394</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000384">
        <property type="protein sequence ID" value="OBZ85547.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N8Z1"/>
    <dbReference type="STRING" id="101091.A0A1C7N8Z1"/>
    <dbReference type="InParanoid" id="A0A1C7N8Z1"/>
    <dbReference type="OrthoDB" id="1103324at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050364">
        <property type="entry name" value="Cytochrome_P450_fung"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46300:SF11">
        <property type="entry name" value="OXIDOREDUCTASE, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46300">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0349">Heme</keyword>
    <keyword evidence="3 4 5" id="KW-0408">Iron</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="1 4 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="2 5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="21"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="4">
        <location>
            <position position="480"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OBZ85547.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="541" mass="61132" checksum="0D2ABA8E2A2EC9E3" modified="2016-11-30" version="1">MEKISEYIGSIRIPFRIHQDHILPIVSISAATLYASYYFLRQSKRSTAMESIKEIPTPGLCYPYVGHMLSLGELPGEQITKWHKELGHIFKLKMGRQTWVMIDDPLLAHKIFVGHGAQTSSRPISIYNHYHYSKGGKGIVFSQPGPVFRSNRAVVLSVLAPKQMENFMKSIEKESSNLAKRLIDATQEKGSVDPKTDLELSSMNVIFYAIFGRSFNSTEDPEFQKLSEITGRSIKYAALDEDLPSFLPIFSIFHFLSGKSKIWHDFIHEVRDPAYTKLIEEAYTKEGPNVVKSLDEYQMDLNEKIVIMCKHLPHQSMIHGTQTNLLGIADLVAAGSDTVAITLSWILAILCNYPEVQKSAIDEIDMFVTKHNRVPTFADRLDVPLCISIMKECMRFKPTTAFGLPHSASSDILVDGYFIPKDTVIISSMQSMHYDAERYPEPNVFDPERFLNNLKTMNASVNGSFEDRDHFNFGWGRRICPGIYLAEAEIFFAVIQLLARANIEPADEGLPVLEGAVNAGLSLRPLPYKVKFVRRTDALIQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-06-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N913</accession>
    <name>A0A1C7N913_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_06842</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000433">
        <property type="protein sequence ID" value="OBZ85106.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N913"/>
    <dbReference type="InParanoid" id="A0A1C7N913"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ85106.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="64" mass="7383" checksum="36CF31B9621E0D24" modified="2016-11-30" version="1">MISDTDQCNWDNFSDAEPLASFKDESEQEVEAIGLSEYSIEMKEELGKLFSAKFKSMEELRKKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N930</accession>
    <name>A0A1C7N930_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">AB hydrolase-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_06520</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000397">
        <property type="protein sequence ID" value="OBZ85428.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N930"/>
    <dbReference type="STRING" id="101091.A0A1C7N930"/>
    <dbReference type="InParanoid" id="A0A1C7N930"/>
    <dbReference type="OrthoDB" id="6431331at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37471:SF1">
        <property type="entry name" value="AB HYDROLASE-1 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37471">
        <property type="entry name" value="UNNAMED PRODUCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="33"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="178"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="254"/>
            <end position="275"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ85428.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="477" mass="56166" checksum="32928BD68338B18D" modified="2016-11-30" version="1">MLTRLFSKRLLLPCLFILPCTYAYLTATFHLIVISSIWGLIECLFYLYFVQTKQRLQSITKPERLLTKTERAALFRQCINTIKDFRAWCEGWFYYRTDYTHPSIHQIRRQNIAQWLAWAFWHDHLEHVQKEKAWAEELEWMIREAEDRFSYQFSDGLNPDVECIRLNLDPVNAVHRPLLAYVGIYLITQCFNLVGLQWCWGFTPSHSTTHSWGGPIQLLDHLYQSLFNLASHQPKDKITYWYRAPTDGQSKTPIVFVHGIGVGVLSYAEWISLLLSRLSDRPIFLVELPYVAMRMVDTVPTATETTKEVRQMLHQYGYDKAVYVSHSLGTAVTSWIIKLAPDTVAGTVMIDPICFLLHYHHVAFNFVHRLPRQLIEYLMYYGASREMYISHYISRHFQWFESICFVEHIQKTTLNNMAVFLSEKDRIVGSEDVYHYLLEHGINTYVMKGLEHAMFLINRKWKNTIIHQIETISSKTD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N9B3</accession>
    <name>A0A1C7N9B3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">DASH complex subunit ASK1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">A0J61_06247</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Chromosome</location>
            <location evidence="3">Centromere</location>
            <location evidence="3">Kinetochore</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
            <location evidence="2">Cytoskeleton</location>
            <location evidence="2">Spindle</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the DASH complex ASK1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000368">
        <property type="protein sequence ID" value="OBZ85705.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N9B3"/>
    <dbReference type="STRING" id="101091.A0A1C7N9B3"/>
    <dbReference type="InParanoid" id="A0A1C7N9B3"/>
    <dbReference type="OrthoDB" id="5573898at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042729">
        <property type="term" value="C:DASH complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072686">
        <property type="term" value="C:mitotic spindle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044732">
        <property type="term" value="C:mitotic spindle pole body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008608">
        <property type="term" value="P:attachment of spindle microtubules to kinetochore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013964">
        <property type="entry name" value="DASH_Ask1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28200">
        <property type="entry name" value="DASH COMPLEX SUBUNIT ASK1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28200:SF1">
        <property type="entry name" value="DASH COMPLEX SUBUNIT ASK1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08655">
        <property type="entry name" value="DASH_Ask1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="14" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="8" id="KW-0132">Cell division</keyword>
    <keyword evidence="15" id="KW-0137">Centromere</keyword>
    <keyword evidence="6" id="KW-0158">Chromosome</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="12" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="11" id="KW-0995">Kinetochore</keyword>
    <keyword evidence="9" id="KW-0493">Microtubule</keyword>
    <keyword evidence="10" id="KW-0498">Mitosis</keyword>
    <keyword evidence="13" id="KW-0539">Nucleus</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="111"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="249"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="16">
        <location>
            <begin position="116"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="16">
        <location>
            <begin position="261"/>
            <end position="272"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004629"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010731"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00014520"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022838"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="OBZ85705.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="309" mass="35868" checksum="94100A842D75C5E1" modified="2016-11-30" version="1">MSIPLTQTEAEEKLEEFQQQVTLNLQEIDKNFAECTRIINELTIPNVERYAEQTNLIWGLSKDWSWFFDSMSLRTRMPAYENDSLFPLFSPSSTHREHTMSNISAYVKGLRKQMQEESTQDTTTSEYSKPSQLDWTKRAESTRSPPRIMPYLTEPSSLANTPRNEAARILTENSLQAVDLGETVSPDDLYMAFELQDVTAGQDLQEEGRLSPLLKKDWGSTDLMETESEEQRRNFDRFYQKRQTSSFQTSEHNSWHWPSRVSHSPSNRYQRTQQLIQQEAEPGLVGTPTIERVLDRKQLNLKSAKEDDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N9B6</accession>
    <name>A0A1C7N9B6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">SAGA complex subunit spt20</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">spt20</name>
        <name evidence="3" type="ORF">A0J61_06276</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000372">
        <property type="protein sequence ID" value="OBZ85671.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N9B6"/>
    <dbReference type="STRING" id="101091.A0A1C7N9B6"/>
    <dbReference type="InParanoid" id="A0A1C7N9B6"/>
    <dbReference type="OrthoDB" id="1932706at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000124">
        <property type="term" value="C:SAGA complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003712">
        <property type="term" value="F:transcription coregulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021950">
        <property type="entry name" value="Spt20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046468">
        <property type="entry name" value="Spt20-like_SEP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13526">
        <property type="entry name" value="TRANSCRIPTION FACTOR SPT20 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13526:SF8">
        <property type="entry name" value="TRANSCRIPTION FACTOR SPT20 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12090">
        <property type="entry name" value="Spt20_SEP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Spt20-like SEP" evidence="2">
        <location>
            <begin position="55"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="377"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="482"/>
            <end position="542"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="14"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="389"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="482"/>
            <end position="531"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="532"/>
            <end position="542"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="542"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ85671.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="542" mass="60905" checksum="CE8F32C7E91DA952" modified="2016-11-30" version="1" fragment="single">MASTKVMAELHSKQAANVSPSLSKKSASRWHASQSNHKSQPLKDENELLRRHANSPPSLCLHLYPTYFKFEHEDGFFSYKSQFKDFLICVKERRLPGDLVDVFNEASCRYYDGCLLVDIHDHRAQGAQNTTKRIVMKPTAESIWTDIALLSEEWGVSYTEDFALQIEAQILIATEEPLCLDPSIQVSRISNAIEYASGRRRPKRKMKYNSVEREQKLAKKAESIKLMTLMDARAKRTFPFEPSFGKISFIHDWRSKRTKLGAEALPAIDTKKGKGRKGVMEPPVLSDGRKCTRTVRFERTEGDRKVYTIVNIYVNNGEYDGVFRWGTVYDTSINGGSIDFKLGTENLVEAYILHLKSTYGQFNAVICDNTNVNAVPPSPSTIRLPNGITQPAPQRPTQPTQPAQNQTQSVQIQAHQVPQQAPQQVQQLTQQGQQARPAQPLTNLQIQQLHAQQNRAMQAKAAMLPPHQRALLAQAQAQAQAQAQAQAQTSNQPPQNQQPSSQQTPQQTPQQTPQQTPQQTPQQTPQQVPQQLSTGLTQAQIQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N9M7</accession>
    <name>A0A1C7N9M7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">PX domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_06579</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000403">
        <property type="protein sequence ID" value="OBZ85379.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N9M7"/>
    <dbReference type="FunCoup" id="A0A1C7N9M7">
        <property type="interactions" value="20"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N9M7"/>
    <dbReference type="InParanoid" id="A0A1C7N9M7"/>
    <dbReference type="OrthoDB" id="2117459at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035091">
        <property type="term" value="F:phosphatidylinositol binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1520.10">
        <property type="entry name" value="Phox-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047168">
        <property type="entry name" value="LEC1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024554">
        <property type="entry name" value="LEC1-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024555">
        <property type="entry name" value="PX-associated"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001683">
        <property type="entry name" value="PX_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036871">
        <property type="entry name" value="PX_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47185">
        <property type="entry name" value="PX DOMAIN-CONTAINING PROTEIN YPR097W"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47185:SF1">
        <property type="entry name" value="PX DOMAIN-CONTAINING PROTEIN YPR097W"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12825">
        <property type="entry name" value="DUF3818"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00787">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12828">
        <property type="entry name" value="PXB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00312">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64268">
        <property type="entry name" value="PX domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50195">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PX" evidence="2">
        <location>
            <begin position="150"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="735"/>
            <end position="773"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="735"/>
            <end position="746"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="759"/>
            <end position="770"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ85379.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="800" mass="92580" checksum="BBE1DD3E197FF9F0" modified="2016-11-30" version="1">MNLSPKQLHYFKRELITEQLDKEINLLNKSTSDTFLSDQKNDADFPLLSYAFDNLIAEFPLLKHTRDDQFWPKCQLLLEEFNKAHLGGNYAPSKMASTLHRKKIQHKIQKSLVFAFCACIKTIQGPEESIRIDQPISSDTSASTPASLNVNIVAVRQVTEKKTLRDVSHAEFMIESQGPHDKEPIYVARRHGDFRRLREELKYHFRQQHLSIPLVPSKSSQQTTFYRERDRLLLRSFLNQLIREPQIQKSNVLKQFLTDRPVLFTPEEEQDALAREQADQKRWSEQEKFKKELDRRVLELNDTLHQLKHQIIQPGGLVGVFDIVKKTKSIQDLPDSLKKAFEWGRVSFAFALHRQFVSADTAIDNFNSLKHTHSLMPYKTLSVILRFSNPMMIVKSVLDLFLAQPFGQKSLFQRHSYDKLCFNTVDNRILISNMSEESKSADKEIKQLENAIQDKIICQKLYQAVRTPLAKDYQPIKASRRIELLAVLNQQAIEPCLTEDQFAFAEKNLDSLVRLWELYAQQYEQERMTDLIFQGVTGELLKEFISVFYQPLAQVYKAADISTTIRHVALFVDDLIHVVNEQADQEAVTVSDSIQPFIDLVQRHEANFYQFVHNVHSQESSTVFDELVQYVDNLFTFVAQGIPGEVDLDSCVARAGIQSEQDKTILRAEIDAICDYRYKQKVYRFERQKKKMMAQSPADIEPVYPSQEQQSLDLMTNTKDMPDNFQDMDELVFDEEDDEEDDEEDSQSNHSFEVDHGSNHSNSSHSSGSHVSHKGIERPVLQLIPTVLSHFMKDVRGLMN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NA27</accession>
    <name>A0A1C7NA27_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">SET domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_06127</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000355">
        <property type="protein sequence ID" value="OBZ85818.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NA27"/>
    <dbReference type="STRING" id="101091.A0A1C7NA27"/>
    <dbReference type="InParanoid" id="A0A1C7NA27"/>
    <dbReference type="OrthoDB" id="265717at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd20071">
        <property type="entry name" value="SET_SMYD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.270.10">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050869">
        <property type="entry name" value="H3K4_H4K5_MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001214">
        <property type="entry name" value="SET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046341">
        <property type="entry name" value="SET_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12197">
        <property type="entry name" value="HISTONE-LYSINE N-METHYLTRANSFERASE SMYD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12197:SF292">
        <property type="entry name" value="SET DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00856">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82199">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50280">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SET" evidence="2">
        <location>
            <begin position="20"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="92"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="100"/>
            <end position="123"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ85818.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="626" mass="71497" checksum="1F3B902D4157769B" modified="2016-11-30" version="1">MTSVSQLGLNTVVNQQEFQELVVIKECPTVGRSLVAKKPLVPGDIVLVETPLIQYDLEPTCRSNKSPYYSKKLWKLLTNMVRDEDALDTQQLNFNHESNNEEEDQYSQDDSEYEDDEEEEEEDEKRVDAQSEFYPGVPAAIIAYLHIHPPPSFNNVRRRKQFNQNDFDFFYFPNTDVEPAWLDHKTIKLIHSVTQKVVDTVPLYAHVDPFDLRSFVLKIYSNAHTVSLPRTRTAPTHSSKRSRREHYKAKFGDDATFWGEDAVEPPNTPTIALLRWGSKFAHSCSPNMFLRFEPSRNVMVFTITKPLAEGDVLTFSYLPEDDSIVGGLIYGATLDRQAKLEKFKFFKCACERCLDWDWARGMICEECKEPISYRTEDKWTCLACGSNTNDEQMSFVGDSEKHVQTTVMNFFSRVFGGRRLTQNTIQMLEPQLTDLVAQYNVPKTHWTFAVIQSILAAYHLTLFPQTYGKGLASQMGMTLQGLEESLAYLEFLNEAIHTPKHPQAKSKGNPMAVFFAGWRILSIVIDLVMDSTENKYANAAFEQESDSDDEDGPPSPTLKPVIQNEPVLIPLDPSWVAPVSKISCIANKEWIPLVEQVFRSQEAIVVQDMIRQIKGLDQRLDELSKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NA28</accession>
    <name>A0A1C7NA28_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Lysine-specific permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">lysP_1</name>
        <name evidence="9" type="ORF">A0J61_05973</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000340">
        <property type="protein sequence ID" value="OBZ85985.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NA28"/>
    <dbReference type="FunCoup" id="A0A1C7NA28">
        <property type="interactions" value="426"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NA28"/>
    <dbReference type="InParanoid" id="A0A1C7NA28"/>
    <dbReference type="OrthoDB" id="3900342at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030134">
        <property type="term" value="C:COPII-coated ER to Golgi transport vesicle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000328">
        <property type="term" value="C:fungal-type vacuole lumen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005771">
        <property type="term" value="C:multivesicular body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001761">
        <property type="term" value="F:beta-alanine transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015192">
        <property type="term" value="F:L-phenylalanine transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015193">
        <property type="term" value="F:L-proline transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015203">
        <property type="term" value="F:polyamine transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1740.10:FF:000001">
        <property type="entry name" value="Amino acid permease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1740.10">
        <property type="entry name" value="Amino acid/polyamine transporter I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004841">
        <property type="entry name" value="AA-permease/SLC12A_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004840">
        <property type="entry name" value="Amino_acid_permease_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050524">
        <property type="entry name" value="APC_YAT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43341">
        <property type="entry name" value="AMINO ACID PERMEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43341:SF1">
        <property type="entry name" value="GENERAL AMINO-ACID PERMEASE GAP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00324">
        <property type="entry name" value="AA_permease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006060">
        <property type="entry name" value="AA_transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00218">
        <property type="entry name" value="AMINO_ACID_PERMEASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0029">Amino-acid transport</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="47"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="75"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="128"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="157"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="187"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="228"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="273"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="313"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="371"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="398"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="449"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="473"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="domain" description="Amino acid permease/ SLC12A" evidence="8">
        <location>
            <begin position="47"/>
            <end position="499"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OBZ85985.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="543" mass="59237" checksum="7B6791CF5DDAB2E9" modified="2016-11-30" version="1">MSENKLKVDYKEETKIETLTDEHDRITVSSLESQEHPQLKRSLKSRHLAMISIGGVIGQGLFLSSGGNLAKAGPAGALIAYGIIGFIVFWVTFSLGEMATYIPVSGSFTVFCRRFVDTSFGTTIGYNYWACWAIIVASELTALPLVMQFWTTKVPDWAWSGIWLVIIFLLNMNGARSYAEAEYWFSVIKILAVLVFIIVGCITSGGLIGNTTPHEVYGFKYWSNPGAFSNGALGVLNAFVLASFSMQGTEIVGITAGECENPVKQVPRAIKNVFWRIIIFYLGSVFIMGMLIAYDDPRNLSGSSSVTVSPFTIVFELAGLNSVAHIMNAVILITVLSCANSGMYVSSRMLCALSKEGLAHPKLAHISSRGVPIYALICTTAVCLITFATSFIPGKALFIVLTDLSGIAGFVTWGGICFAHYRFRKALKHQGRRVADLPITTPFHPFGDIFGMIACTVIALIAGYSYFVPADPVGLIGNYGGLVACLILYVALKIKTKSRMVPIDQIDLDTGRADFSNVKEDEEIEISGPLYKRIFKRAINVLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NA34</accession>
    <name>A0A1C7NA34_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Leukotriene-B(4) omega-hydroxylase 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">Cyp4f3</name>
        <name evidence="9" type="ORF">A0J61_06047</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1 8">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000347">
        <property type="protein sequence ID" value="OBZ85901.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NA34"/>
    <dbReference type="STRING" id="101091.A0A1C7NA34"/>
    <dbReference type="InParanoid" id="A0A1C7NA34"/>
    <dbReference type="OrthoDB" id="1470350at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050196">
        <property type="entry name" value="Cytochrome_P450_Monoox"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24291:SF50">
        <property type="entry name" value="BIFUNCTIONAL ALBAFLAVENONE MONOOXYGENASE_TERPENE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24291">
        <property type="entry name" value="CYTOCHROME P450 FAMILY 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 7 8" id="KW-0349">Heme</keyword>
    <keyword evidence="5 7 8" id="KW-0408">Iron</keyword>
    <keyword evidence="3 7 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 8" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="4 8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" description="axial binding residue" evidence="7">
        <location>
            <position position="493"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OBZ85901.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="552" mass="63514" checksum="EF8736A8D2B76217" modified="2016-11-30" version="1">MVLVADLIANSQHQFNFWIHRILPQLRKKTGVISVGAAVILTLLYNTLQKFNRPPKQLRHLPYISYFTFLKYSFRDALFETFSKEMTMPLVRSNGIYMRPTVEGWSVQVANPIAVKQILLKPESSFPKANSNVGTPDTLIHKFIGGPNIVLLSGKDWKRHRKIANPAFQRSMPVKTFGHLTSKMYQAMEDLGTDTVDVFDLFERWTLDAIGITGFGKSVFVSLENTADSQETHIDFDFNALGDRNNKWVHYYDSVKDGMSNPFYIFFPSFDTKFVRFIKKRKQIHDNLEKFLANIDMMIEQKRKQVHEKAHTVRDEDKDLLTLMIESGLSEGEDKLSVDELRSNLCIFFLAGHDTTANTLAFALYELAKNPELQEKARKEALEILGDAPEDVIPTIEQTKQMTYINMVIKETMRRHTPVYSTTNRVALEDLELAGNYIPKGSELSVDIYNLHHNPDVWHDPYQFKPERFIPGGEADQHQGIGWVPFSNGGRQCIGMNFSLAEQRVVLSMMLRKFKWSLPPNSPHRDAIQKRGIAWGLVITRETLDITFEKRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NBH3</accession>
    <name>A0A1C7NBH3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">A0J61_05559</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000303">
        <property type="protein sequence ID" value="OBZ86391.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NBH3"/>
    <dbReference type="FunCoup" id="A0A1C7NBH3">
        <property type="interactions" value="79"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NBH3"/>
    <dbReference type="InParanoid" id="A0A1C7NBH3"/>
    <dbReference type="OrthoDB" id="6730379at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791:SF63">
        <property type="entry name" value="HIGH AFFINITY CYSTEINE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43791">
        <property type="entry name" value="PERMEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="42"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="80"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="110"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="134"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="169"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="203"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="272"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="308"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="335"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="363"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="394"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="427"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="42"/>
            <end position="452"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OBZ86391.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="485" mass="54718" checksum="C7AEFCD16BDE6D6B" modified="2016-11-30" version="1">MTDIEKVEIETIGSVKSRRLDPVPPVKTDAEKKLLHKINSTFMPFACLILFIQFVDKSTLSTISVLDQFYEDTHISRDQYSWLGSIFYLGFLCMQLPNNYMMQKFPLSRYVGTMLVIWGAVLFSIGFAKNFSQLAALRFLLGLFEAITYPTMFLLIATMYRRSEQVLGFGVMFLSNSVGMILGGVIGVGFINMPTVNYISAWQWAMIIYGSITMLMGLIYFVFLPDRPDSRWFRLTEEEKLIVKERVRDNAVVRTFNINRDQIKEALKEPRLYCYCLISLLIELQNGALTTFQSLIISDLGFSSTNAVLLTIPSGVFALILVAGSSYLSKKWGEIIWMAIAMCTISVVGLILLAAIPSGGIKLLGLYLSWGCTPTYVLMQASITSNVSGYTKKIFYTGGNMISYTLGNFIGPLLLRNKDAPRYLTGMGVYIAANVLVILLFIYLRFSYVQANKRHNLDQKTDFVALPNDLEDLTDIQNPNFVYKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NBY9</accession>
    <name>A0A1C7NBY9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">CWF19-like protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">cwf19l1</name>
        <name evidence="6" type="ORF">A0J61_05335</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000285">
        <property type="protein sequence ID" value="OBZ86615.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NBY9"/>
    <dbReference type="FunCoup" id="A0A1C7NBY9">
        <property type="interactions" value="1111"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NBY9"/>
    <dbReference type="InParanoid" id="A0A1C7NBY9"/>
    <dbReference type="OrthoDB" id="444325at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071014">
        <property type="term" value="C:post-mRNA release spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000974">
        <property type="term" value="C:Prp19 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061632">
        <property type="term" value="F:RNA lariat debranching enzyme activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07380">
        <property type="entry name" value="MPP_CWF19_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.428.10">
        <property type="entry name" value="HIT-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.60.10">
        <property type="entry name" value="Zinc finger, CCHC-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040194">
        <property type="entry name" value="Cwf19-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006768">
        <property type="entry name" value="Cwf19-like_C_dom-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006767">
        <property type="entry name" value="Cwf19-like_C_dom-2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036265">
        <property type="entry name" value="HIT-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025829">
        <property type="entry name" value="Zn_knuckle_CX2CX3GHX4C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001878">
        <property type="entry name" value="Znf_CCHC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036875">
        <property type="entry name" value="Znf_CCHC_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12072">
        <property type="entry name" value="CWF19, CELL CYCLE CONTROL PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12072:SF4">
        <property type="entry name" value="CWF19-LIKE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04677">
        <property type="entry name" value="CwfJ_C_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04676">
        <property type="entry name" value="CwfJ_C_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13696">
        <property type="entry name" value="zf-CCHC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00343">
        <property type="entry name" value="ZnF_C2HC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54197">
        <property type="entry name" value="HIT-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57756">
        <property type="entry name" value="Retrovirus zinc finger-like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50158">
        <property type="entry name" value="ZF_CCHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="CCHC-type" evidence="5">
        <location>
            <begin position="306"/>
            <end position="320"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OBZ86615.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="575" mass="64533" checksum="2E50590E556C68DF" modified="2016-11-30" version="1">MTDNLKVLVTGSANGQFEALFAKVKQIHEKYGPFQVHLCVGDFFGSDTSSLQALIDNQIEVPLTTYFINGQQPLPDLAQHHLQSTDGELCSNLFYLGKQGVLTTSEGLKIAFLSGQFDEHVSSDAAFTSSDIQKLCLTKMPVSAPPGVDFLLTHQWPKDVNQGSQQTLNLSDEKSHVCISQLAAALKPRYHFAASQAQFFEREPYQNIISGLAAQEERPAGHVTRFIGLADVLNTQKQRWFYAFNLVPLSKLEKEALESPENTTECPFAQSVIGQKRKLNEGEQENYFWQDNKRTKSNQPPPGYVCKRCKVEGHYIKDCPMAHQGPPNGYVCKICQGTDHYVTQCPQQSKAKLDACWFCLANPNLEKHLIVSIGSELYMTLAKGPVVSASNPECQVPGEGHVLIIPITHYPTFGLVPPESQKEVMTELVKYKSALRTFFQQYNQDMIVFEVSRDSQRGLTHAHLQVVPIPKSKSDQVEKVARELGVAANIDFVDRVPNNPEIPYFKLDLPNGKSLVHVIQPRERFNLQFGRLVAATVLGSPEREDWKTCGQTEEEEREHANRFKEAFKPYDFSLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NCD3</accession>
    <name>A0A1C7NCD3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Isoleucine--tRNA ligase, cytoplasmic</fullName>
            <ecNumber evidence="3">6.1.1.5</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Isoleucyl-tRNA synthetase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="13">Probable isoleucine--tRNA ligase, cytoplasmic</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="17" type="primary">irs1</name>
        <name evidence="17" type="ORF">A0J61_05292</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>tRNA(Ile) + L-isoleucine + ATP = L-isoleucyl-tRNA(Ile) + AMP + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:9666"/>
            <dbReference type="Rhea" id="RHEA-COMP:9695"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58045"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78528"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.5"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 14">Belongs to the class-I aminoacyl-tRNA synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.5" evidence="3"/>
    <dbReference type="EMBL" id="LUGH01000282">
        <property type="protein sequence ID" value="OBZ86658.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NCD3"/>
    <dbReference type="FunCoup" id="A0A1C7NCD3">
        <property type="interactions" value="697"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NCD3"/>
    <dbReference type="InParanoid" id="A0A1C7NCD3"/>
    <dbReference type="OrthoDB" id="1706657at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002161">
        <property type="term" value="F:aminoacyl-tRNA deacylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004822">
        <property type="term" value="F:isoleucine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990825">
        <property type="term" value="F:sequence-specific mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006428">
        <property type="term" value="P:isoleucyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd07961">
        <property type="entry name" value="Anticodon_Ia_Ile_ABEc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00818">
        <property type="entry name" value="IleRS_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.740.10:FF:000044">
        <property type="entry name" value="Isoleucine--tRNA ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.730.10:FF:000004">
        <property type="entry name" value="Isoleucyl-tRNA synthetase, cytoplasmic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.620:FF:000023">
        <property type="entry name" value="Isoleucyl-tRNA synthetase,cytoplasmic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.620:FF:000050">
        <property type="entry name" value="Isoleucyl-tRNA synthetase,cytoplasmic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.730.10">
        <property type="entry name" value="Isoleucyl-tRNA Synthetase, Domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02003">
        <property type="entry name" value="Ile_tRNA_synth_type2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001412">
        <property type="entry name" value="aa-tRNA-synth_I_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002300">
        <property type="entry name" value="aa-tRNA-synth_Ia"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033709">
        <property type="entry name" value="Anticodon_Ile_ABEc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002301">
        <property type="entry name" value="Ile-tRNA-ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023586">
        <property type="entry name" value="Ile-tRNA-ligase_type2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013155">
        <property type="entry name" value="M/V/L/I-tRNA-synth_anticd-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009080">
        <property type="entry name" value="tRNAsynth_Ia_anticodon-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009008">
        <property type="entry name" value="Val/Leu/Ile-tRNA-synth_edit"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00392">
        <property type="entry name" value="ileS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42780:SF1">
        <property type="entry name" value="ISOLEUCINE--TRNA LIGASE, CYTOPLASMIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42780">
        <property type="entry name" value="SOLEUCYL-TRNA SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08264">
        <property type="entry name" value="Anticodon_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19302">
        <property type="entry name" value="DUF5915"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00133">
        <property type="entry name" value="tRNA-synt_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00984">
        <property type="entry name" value="TRNASYNTHILE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47323">
        <property type="entry name" value="Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52374">
        <property type="entry name" value="Nucleotidylyl transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50677">
        <property type="entry name" value="ValRS/IleRS/LeuRS editing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00178">
        <property type="entry name" value="AA_TRNA_LIGASE_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 14" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="7 14" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 14 17" id="KW-0436">Ligase</keyword>
    <keyword evidence="6 14" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8 14" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aminoacyl-tRNA synthetase class Ia" evidence="15">
        <location>
            <begin position="18"/>
            <end position="642"/>
        </location>
    </feature>
    <feature type="domain" description="Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding" evidence="16">
        <location>
            <begin position="696"/>
            <end position="851"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005594"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013165"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00032665"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00048359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00069879"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00072822"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU363035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF00133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF08264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="OBZ86658.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="1074" mass="124094" checksum="6187281185EA2B80" modified="2016-11-30" version="1">MSLADLSGQFNFPKEEEKILEFWKEIDAFQTSMKLNKDKPVFAFYDGPPFATGLPHYGHLLAGTIKDIVTRYAHNTGHHVERRFGWDTHGLPVEYEIDKKLGITGKHDVMKMGIDKYNAECRAIVMRYAGEWRKTVERMARWIDFDNDYKTLNPTFMETVWWVFKQLFEKGQVYRGQKVMPYSTGCTTPLSNFESSQNYKDVNDPAVVVGFPLVSDPSVQLLAWTTTPWTLPSNMAVCVHPEFEYVKIRDEATGNTYILMEKRLTMLYKDPKKAKFTVLEKYKGADMAGWEYVPMFDFFAEEFKGKAFKVLVDTYVTDDSGTGIVHNSPAFGEDDYRVCLSNSVITADGHLPCPVDESGIFTEEVPEYKGMYVKDADKVIQKDIKAKNRMIVQSQFMHSYPFCWRSDTPLIYKAVPAWFVRVTPIIDKILANNEQMRWVPSFVQEKRFANWISNARDWNISRNRYWGTPIPIWVSEDFEEIVCVGSIAELEELSGVSPITDIHRESIDSITIPSKKGKGVLRRIEEVFDCWFESGSMPYAQQHYPFENAEKVQSSFPADFISEGIDQTRGWFYTLLVLSTHLFDKPPAKNVIVSGLVLAADGKKMSKRLKNYPEPGLVMDKFGSDALRLYLINSPVVRAETLKFREEGVKDVISKVFLPWYNAYKFFLTQTAVLKKDFDYEFQYDAHIKKSDNVMDRWVLASCQSLIKFIREEMGAYRLYTVVPRLLNMVDTLTNWYVRFNRKRLKGENGLDDAKLAMNTLYEVLFTLCLTMAPFTPYLVENMYQNLKNFAPKNPNVVDDRSIHFLDFPTVREEYFDPEIERAVGRMQAVIELGRTIRERKNISLKTPLKELVVIHNDPQYHADVKALESYIVEELNVRTLVVTDNEDKYGIKYKAEADWKTLGQKLKKDAMKVKKGLPELTSDQIKEFVQTKEIMVSGIKVTDEDLNVVRYFDASDDALYEANTDKDSLVLMDVKLYPELEEEGVAREIINRVQRLRKKANLLPTDDINMYYNFTADLSAELEAVIKNQEATLVKVIKKPLQPFDKMTSDEKLIAEEEQDVNGIKFNLIFAKH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NCS1</accession>
    <name>A0A1C7NCS1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">chitinase</fullName>
            <ecNumber evidence="2">3.2.1.14</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">CHI1_2</name>
        <name evidence="12" type="ORF">A0J61_05031</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Random endo-hydrolysis of N-acetyl-beta-D-glucosaminide (1-&gt;4)-beta-linkages in chitin and chitodextrins.</text>
            <dbReference type="EC" id="3.2.1.14"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the glycosyl hydrolase 18 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.14" evidence="2"/>
    <dbReference type="EMBL" id="LUGH01000261">
        <property type="protein sequence ID" value="OBZ86913.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NCS1"/>
    <dbReference type="InParanoid" id="A0A1C7NCS1"/>
    <dbReference type="OrthoDB" id="6020543at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008843">
        <property type="term" value="F:endochitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006032">
        <property type="term" value="P:chitin catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000272">
        <property type="term" value="P:polysaccharide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02877">
        <property type="entry name" value="GH18_hevamine_XipI_class_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045321">
        <property type="entry name" value="Cts1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001223">
        <property type="entry name" value="Glyco_hydro18_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001579">
        <property type="entry name" value="Glyco_hydro_18_chit_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050542">
        <property type="entry name" value="Glycosyl_Hydrlase18_Chitinase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45708">
        <property type="entry name" value="ENDOCHITINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45708:SF49">
        <property type="entry name" value="ENDOCHITINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00704">
        <property type="entry name" value="Glyco_hydro_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01095">
        <property type="entry name" value="GH18_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51910">
        <property type="entry name" value="GH18_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="4" id="KW-0146">Chitin degradation</keyword>
    <keyword evidence="6 8" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="3 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GH18" evidence="11">
        <location>
            <begin position="13"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="350"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="10">
        <location>
            <begin position="359"/>
            <end position="368"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000822"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000489"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU004453"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="OBZ86913.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="391" mass="40860" checksum="DF6D5226492A60CE" modified="2016-11-30" version="1">MSAAQARYSSSKPNVFYYWGQNSAGGSSTQSSLATYCDSGLVDGVILSFLHVFNIGGDPGMNFAGACKTTFPDSNLLSCPNIASDIKTCQSKGIKVILSLGGASGSYGFDSDSQAKTFADTLWNLFGGGSAEDRPFGDTEIDGIDLDIEGGQPTGYVSLVNAVRSKFGSDFLVGAAPQCPFPDVILGSVIDSVGFDYVNVQFYNNYCSAAGGSFNFDTWAKWATSTSPNKNVKVLFTIPGSSTAAGTGYAPISTIQSIVPKLASEYPNTFGGVSVWDASQAWNNGDFASALYRSVKSGDSAPSYSTDKKSSESSSSVETATTAIASATISSPAIASATVSNTQNQKQYVKTNRLCSKLSKSKSTKSCKKXLDGTKSQSESSGPEAGHNKRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NCY7</accession>
    <name>A0A1C7NCY7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_04992</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000257">
        <property type="protein sequence ID" value="OBZ86957.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NCY7"/>
    <dbReference type="InParanoid" id="A0A1C7NCY7"/>
    <dbReference type="OrthoDB" id="2220585at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ86957.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="221" mass="24657" checksum="E96975E8ED6497C1" modified="2016-11-30" version="1">MFATEITAPGEKVDIDYESLAHCLNSSTVPSTSPSEHKKRRVSTAHIIPFEFPNGMESFAFDELASECAQFLDSPTIDENVLHFASSIVTIIGSPTVTDSEEVKRRIEQVLPTQHGYKHRRGMKISEEDCIKLCSLADRAIHLPVGKPTNVEIVDDDIGDGNDNAADKNYGMNDVQYIRHTNYNHKKQQIYKTNAKLETGTIEYDFDVTPYGSDVEGQTMA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7ND31</accession>
    <name>A0A1C7ND31_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">DNA 3'-5' helicase</fullName>
            <ecNumber evidence="8">5.6.2.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">SSL2</name>
        <name evidence="14" type="ORF">A0J61_05013</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="5.6.2.4"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>Couples ATP hydrolysis with the unwinding of duplex DNA by translocating in the 3'-5' direction.</text>
            <dbReference type="EC" id="5.6.2.4"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the helicase family. RAD25/XPB subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.6.2.4" evidence="8"/>
    <dbReference type="EMBL" id="LUGH01000259">
        <property type="protein sequence ID" value="OBZ86938.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7ND31"/>
    <dbReference type="STRING" id="101091.A0A1C7ND31"/>
    <dbReference type="InParanoid" id="A0A1C7ND31"/>
    <dbReference type="OrthoDB" id="10262986at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000112">
        <property type="term" value="C:nucleotide-excision repair factor 3 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005675">
        <property type="term" value="C:transcription factor TFIIH holo complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097550">
        <property type="term" value="C:transcription preinitiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043138">
        <property type="term" value="F:3'-5' DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006289">
        <property type="term" value="P:nucleotide-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006367">
        <property type="term" value="P:transcription initiation at RNA polymerase II promoter"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd18789">
        <property type="entry name" value="SF2_C_XPB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050615">
        <property type="entry name" value="ATP-dep_DNA_Helicase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032438">
        <property type="entry name" value="ERCC3_RAD25_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006935">
        <property type="entry name" value="Helicase/UvrB_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001161">
        <property type="entry name" value="XPB/Ssl2"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00603">
        <property type="entry name" value="rad25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11274:SF0">
        <property type="entry name" value="GENERAL TRANSCRIPTION AND DNA REPAIR FACTOR IIH HELICASE SUBUNIT XPB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11274">
        <property type="entry name" value="RAD25/XP-B DNA REPAIR HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16203">
        <property type="entry name" value="ERCC3_RAD25_C"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04851">
        <property type="entry name" value="ResIII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4 14" id="KW-0347">Helicase</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0413">Isomerase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="12">
        <location>
            <begin position="127"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="13">
        <location>
            <begin position="354"/>
            <end position="531"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="25"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="10">
        <location>
            <begin position="568"/>
            <end position="595"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="37"/>
            <end position="49"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006637"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00034617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00034808"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00048988"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="OBZ86938.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="608" mass="67778" checksum="E24674D50D6B41A3" modified="2016-11-30" version="1">MVLTDDSNDRQKRLADLLAFVQKKKQDSESLNMASNTPPSTTTITTSTTTVTTTTTTAATAAVDPPAAKKQKTPTKSIKKPGAALPNFYFNKDKTCNHLDLPLRPSVEVRPYQKEALDAIVDTTSENPEDHVAQSGIIVLPCGAGKTLTSILVASAIQKPVLVVCSTIIAAEQFSKEFLRFTTLMASKTGMFAGAKKWPYNGPSGVLFTTYTMLVDSKNRTADSKRMSSFIDKTEWGLIILDEVHCVPANNFAKAIGKIKAKVRLGLTATMLREDERIGDLETLVGPTLYHAKWKELADKGYIAKVICTQVESDMSPLVHEAHDSIQSQNNGSLLGHGHHFKTLLAILNPKKMQICQRLIQYHEAKGDKVLVYCDHIDALKLYAEKIGRPFIYGGTPTDEARQLLSRFQIDVPESEEELTWNEIATRRSLKAKQVNTLFLSRIGDTSLDLPAATVLIQVSSHFGSRRQEAQRLGRVLRAKKRNEKGFYSRFYTLVTNDTHEVTFSEKRRQFLEEDCGYGYQIWKVGAEEAGGWSVDAMRDSSSPDDDEVKTDPLTCTIHGADERPYASEQEERKLVEFLSNLKNYQVEKEEDEDEVLMTATAGAKRKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7ND45</accession>
    <name>A0A1C7ND45_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_06654</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000412">
        <property type="protein sequence ID" value="OBZ85294.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7ND45"/>
    <dbReference type="InParanoid" id="A0A1C7ND45"/>
    <dbReference type="OrthoDB" id="2286725at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.30.50">
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ85294.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="194" mass="22460" checksum="2693FC10615E0513" modified="2016-11-30" version="1">MCHVVLTPKYGGVRARLDSQAKYKGSPCCLGCKRFISFAKTKKERGYITTYLLTGHIPSHDLPPTLSVQEVLRRLKARYHQIRSRYNHKVTENKNCPLTLNDLIRIYIKQDQLCQITGFRCYLHDTSLPRQPYWALSLDHIVPVSHQLNNHYVWSADNLQVMSTILNSIKGDANDVEIVDWYKRFLAANMVLID</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NDM2</accession>
    <name>A0A1C7NDM2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Putative deoxyribonuclease TATDN1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">Tatdn1</name>
        <name evidence="6" type="ORF">A0J61_04896</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the metallo-dependent hydrolases superfamily. TatD-type hydrolase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000250">
        <property type="protein sequence ID" value="OBZ87060.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NDM2"/>
    <dbReference type="FunCoup" id="A0A1C7NDM2">
        <property type="interactions" value="255"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NDM2"/>
    <dbReference type="InParanoid" id="A0A1C7NDM2"/>
    <dbReference type="OrthoDB" id="6079689at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008296">
        <property type="term" value="F:3'-5'-DNA exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006309">
        <property type="term" value="P:apoptotic DNA fragmentation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034599">
        <property type="term" value="P:cellular response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd01310">
        <property type="entry name" value="TatD_DNAse"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.140:FF:000040">
        <property type="entry name" value="Putative tatD related deoxyribonuclease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.140">
        <property type="entry name" value="Metal-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018228">
        <property type="entry name" value="DNase_TatD-rel_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001130">
        <property type="entry name" value="TatD-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050891">
        <property type="entry name" value="TatD-type_Hydrolase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10060:SF15">
        <property type="entry name" value="DEOXYRIBONUCLEASE TATDN1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10060">
        <property type="entry name" value="TATD FAMILY DEOXYRIBONUCLEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01026">
        <property type="entry name" value="TatD_DNase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005902">
        <property type="entry name" value="DNase_TatD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="Metallo-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01091">
        <property type="entry name" value="TATD_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0540">Nuclease</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="5">
        <location>
            <position position="115"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="152"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="177"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="225"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>1</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009275"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR005902-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OBZ87060.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="307" mass="35102" checksum="7D9B90EE2784786E" modified="2016-11-30" version="1">MQRIMKFIDIGANLTDPMFRGIYRGKQAHTDDLHLVLQRARDAGVQKIFITGTNLEESKEALELIEQDKDNFLYSTVGCHPTRCTEFKGYKDGPQAYYDALLSLATSKRVIAIGECGLDYDRLQFCDVATQKEYFVKQFDLAEKTQLPMFLHNRNTGNDFYELIQEHRHRFTEGVVHSFTGSMEEMQKLCSLGLYIGVNGCSLKTEENLKVVKAIPEERLMIETDAPWCDIRPTHASYAYLSPEEIKTYAPAAKKKEKFEMGSMVKSRNEPATIGLVLHVVATLRNKDPVELSEIIWKNTLNVFKIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NDQ2</accession>
    <name>A0A1C7NDQ2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Pentacotripeptide-repeat region of PRORP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_04730</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000238">
        <property type="protein sequence ID" value="OBZ87212.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NDQ2"/>
    <dbReference type="STRING" id="101091.A0A1C7NDQ2"/>
    <dbReference type="InParanoid" id="A0A1C7NDQ2"/>
    <dbReference type="OrthoDB" id="185373at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002885">
        <property type="entry name" value="PPR_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00756">
        <property type="entry name" value="PPR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47936:SF1">
        <property type="entry name" value="PENTATRICOPEPTIDE REPEAT-CONTAINING PROTEIN GUN1, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47936">
        <property type="entry name" value="PPR_LONG DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01535">
        <property type="entry name" value="PPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13041">
        <property type="entry name" value="PPR_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51375">
        <property type="entry name" value="PPR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="PPR" evidence="2">
        <location>
            <begin position="148"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="repeat" description="PPR" evidence="2">
        <location>
            <begin position="183"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="repeat" description="PPR" evidence="2">
        <location>
            <begin position="295"/>
            <end position="329"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00708"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ87212.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="412" mass="47643" checksum="445230C0693F820A" modified="2016-11-30" version="1">MNRAFQLIKSPLIQQIRQAHGGVKDPLRLRTVQYSPETSAKLLSAIRRSSPPAVWKAYMELNDANQLNKLPAEYHAMTLQSFQIKRLPAYTPEEISFYRSCMLHILETMKSCGHPPDVRDYNILLDFYGRTKDWTSAQALWSEIKTPTIYSYNHYLHAAVQCKKYEEAFRIFRQLKESPIEPNEVTYNTMIDLYGRLGHIHKADELFMTHFSPQSQKPAKSFLSLLNPTQSSDDTHSYAASVAPLARQISTKSDSLIPSVDTFKALIGAHGRKKNTAGLHHIYSKMMPKHNVTPDIRIYNALIEWYCYSDDVESARKVIMDMEKQAIKPNVVTFNHLFRHEALKRNRPKVAEALVDYMKQEYSIRPLLSMYRTLIRIHNKHNREDEAKRLYGDYILLKTNTAPTTQKTPSHA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NEA2</accession>
    <name>A0A1C7NEA2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Protein tipD</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">tipD</name>
        <name evidence="7" type="ORF">A0J61_04528</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ATG16 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000224">
        <property type="protein sequence ID" value="OBZ87415.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NEA2"/>
    <dbReference type="STRING" id="101091.A0A1C7NEA2"/>
    <dbReference type="InParanoid" id="A0A1C7NEA2"/>
    <dbReference type="OrthoDB" id="538223at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000045">
        <property type="term" value="P:autophagosome assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd22887">
        <property type="entry name" value="Atg16_CCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.170">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045160">
        <property type="entry name" value="ATG16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013923">
        <property type="entry name" value="Autophagy-rel_prot_16_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001632">
        <property type="entry name" value="WD40_G-protein_beta-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19878">
        <property type="entry name" value="AUTOPHAGY PROTEIN 16-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19878:SF8">
        <property type="entry name" value="AUTOPHAGY-RELATED 16, ISOFORM F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08614">
        <property type="entry name" value="ATG16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00319">
        <property type="entry name" value="GPROTEINB"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 4" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="Autophagy-related protein 16" evidence="6">
        <location>
            <begin position="8"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="239"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="281"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="323"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="378"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="408"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="466"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="496"/>
            <end position="534"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="28"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="131"/>
            <end position="194"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005331"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF08614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OBZ87415.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="534" mass="60544" checksum="C4A3CBA6058A4119" modified="2016-11-30" version="1">MSFRDVLMERIQTRDAIESQFHEIIATNNKLLQRTVELEKRTKSLERNNSEQGSSGGNQRLVELDNKIRELNEERAETYKTQSENAQRLVNMNEQLRSRDEKDKKQTEQIQELTQSVRSLSKKCDLQVQQLREKDVAIQILQDELAALQLEIHTTEERNKKLVAENTQLVERWIQKMNEEAEKMNEATQFYERAMEARDATDKQQKQRQSKKKDDLEANSIQNLFYTNIVLPKRAIKKITAHDTDIHCIAASSTGNMFATGGADKKIKLFDAKTGHSIQTLSGALQTITSVCFNISDELILGSCTDNATRIWSLSTHRLIHTLTGHIGKVYAAKFTVNSNQVVSGSHDRTLKIWDLQKGYNIRTIFTFSSCNDVCLMDPDGQILVSGHLDNNVRLWDARTGTGIKELTGVHNGQITSVCMSPDGNTFLTNSRDNTLKIIDVRMYDIVRSFQADSYRTGLNWSRATFSPDGKYIAAGSIDGSLHIWNAKTGKLERVLNEHSSVIAGVAWNPNGDFLYSAEKSKTICMWDTTKETN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NFI1</accession>
    <name>A0A1C7NFI1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="2">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">cki1_1</name>
        <name evidence="14" type="ORF">A0J61_04232</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein kinase superfamily. CK1 Ser/Thr protein kinase family. Casein kinase I subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="2"/>
    <dbReference type="EMBL" id="LUGH01000202">
        <property type="protein sequence ID" value="OBZ87720.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NFI1"/>
    <dbReference type="FunCoup" id="A0A1C7NFI1">
        <property type="interactions" value="530"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NFI1"/>
    <dbReference type="InParanoid" id="A0A1C7NFI1"/>
    <dbReference type="OrthoDB" id="5800476at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005773">
        <property type="term" value="C:vacuole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd14127">
        <property type="entry name" value="STKc_CK1_fungal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000160">
        <property type="entry name" value="Casein kinase I 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000538">
        <property type="entry name" value="Putative Casein kinase I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050235">
        <property type="entry name" value="CK1_Ser-Thr_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11909">
        <property type="entry name" value="CASEIN KINASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 14" id="KW-0418">Kinase</keyword>
    <keyword evidence="5 10 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 11" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="13">
        <location>
            <begin position="26"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="317"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="317"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="333"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="359"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="55"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU000304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="OBZ87720.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="434" mass="49464" checksum="3CE16A4A3F33F0DB" modified="2016-11-30" version="1">MSSALHKNGSGVSSSQSSTNIVGVHYRVGKKLGEGSFGVLYEGLNLLNNQSVAIKFEPRKSDAPQLRDEYRTYKVLAGLPGVPSAYYFGQEGLHNILVIDLLGPSLEDLFDMCGRKHSIKTVAMLAKQMINRVESVHERNLIYRDIKPDNFLIGRPGTKYANMVFLIDYGMAKLYRDPKTKQHIPYRERKSLSGTARYMSINTHLGREQSRRDDLESLGHVFMYFLRGSLPWQGLKAATNKQKYERIGEKKQTTSVKELCDGFPEEFGIYLQYVRKLGFEETPDYDFLRELFNKVLHRMGETDDGVYDWMLLSGKPTETRESRRQAREEQQSKMTLQGTNARRSNTQNSVKRHASHPKLNSNTPNNNMTPPLPTMPSTAAITTSNVNESYTKMPSTPVHGNVNQTDYDQPQHERTKEHRGFWHSLMSLMTCGSH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NG97</accession>
    <name>A0A1C7NG97_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">CTP synthase</fullName>
            <ecNumber evidence="9">6.3.4.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">UTP--ammonia ligase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="primary">ura7_1</name>
        <name evidence="12" type="ORF">A0J61_04364</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8 9">
            <text>UTP + L-glutamine + ATP + H2O = CTP + L-glutamate + ADP + phosphate + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:26426"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:37563"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:46398"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.4.2"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 9">Pyrimidine metabolism; CTP biosynthesis via de novo pathway; CTP from UDP: step 2/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the CTP synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.4.2" evidence="9"/>
    <dbReference type="EMBL" id="LUGH01000212">
        <property type="protein sequence ID" value="OBZ87586.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NG97"/>
    <dbReference type="FunCoup" id="A0A1C7NG97">
        <property type="interactions" value="325"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NG97"/>
    <dbReference type="InParanoid" id="A0A1C7NG97"/>
    <dbReference type="OrthoDB" id="1739076at2759"/>
    <dbReference type="UniPathway" id="UPA00159">
        <property type="reaction ID" value="UER00277"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097268">
        <property type="term" value="C:cytoophidium"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003883">
        <property type="term" value="F:CTP synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042802">
        <property type="term" value="F:identical protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044210">
        <property type="term" value="P:'de novo' CTP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019856">
        <property type="term" value="P:pyrimidine nucleobase biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd03113">
        <property type="entry name" value="CTPS_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01746">
        <property type="entry name" value="GATase1_CTP_Synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000207">
        <property type="entry name" value="CTP synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.880:FF:000005">
        <property type="entry name" value="CTP synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01227">
        <property type="entry name" value="PyrG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004468">
        <property type="entry name" value="CTP_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017456">
        <property type="entry name" value="CTP_synthase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017926">
        <property type="entry name" value="GATASE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033828">
        <property type="entry name" value="GATase1_CTP_Synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003792">
        <property type="entry name" value="PRK05380.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00337">
        <property type="entry name" value="PyrG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11550">
        <property type="entry name" value="CTP SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11550:SF0">
        <property type="entry name" value="CTP SYNTHASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06418">
        <property type="entry name" value="CTP_synth_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00117">
        <property type="entry name" value="GATase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="Class I glutamine amidotransferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51273">
        <property type="entry name" value="GATASE_TYPE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 9" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="3 9" id="KW-0436">Ligase</keyword>
    <keyword evidence="4 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7 9" id="KW-0665">Pyrimidine biosynthesis</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CTP synthase N-terminal" evidence="11">
        <location>
            <begin position="3"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="domain" description="Glutamine amidotransferase" evidence="10">
        <location>
            <begin position="318"/>
            <end position="554"/>
        </location>
    </feature>
    <feature type="unsure residue" description="D or N" evidence="12">
        <location>
            <position position="399"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00047781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU810713"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF06418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="OBZ87586.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="565" mass="62223" checksum="233D7A852231DC23" modified="2016-11-30" version="1">MTKYIVVSGGVISGIGKGVIASSTGTLLKTLGLRVTAIKIDPYLNIDAGLMSPLDHGEVFVLNDGGEVDLDLGNYERFLDVELSRINNITTGKIYREVIEKERKGDYLGKTVQVVPHVTDAIQSWVERVADIPVDESGEKPDVCIIELGGTVGDIESAPFVEAMRQFQFRVGHDNFCLIHVSLVPVVGSVGEQKTKPTQMSVRDLRGAGLSPDLIACRSSKILDPSVAAKISMFCHVAPEQVLAVHDVSSVYHVPILMRDSGIIDFFRRRLNLDELKVSDERRLAGEALWTKWTTLAGSYEHIHENVTIALVGKYTDLHDSYISVYKALEHAALACKRKIVIKWIEATDLEADALKADPIKYHDSWQALCSSDGILVPGGFGGRGIEGMIMAAKWAREDKIPYLGICLGMQIAVIEFARNVCGMADADSAEMNPDTPTPVVVYMPEISKTHMGGTMRLGLRPTVFQEGTENSRVRKLYGGKPSIDERHRHRYEVNPELAGQIEAKGLKFVGKDETGQRMEIVELDDHPYFVGAQYHPEYLTRPLNPCPLFKGLILASIGQLDASL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NGI8</accession>
    <name>A0A1C7NGI8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_03696</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000164">
        <property type="protein sequence ID" value="OBZ88251.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NGI8"/>
    <dbReference type="InParanoid" id="A0A1C7NGI8"/>
    <dbReference type="OrthoDB" id="2377933at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="58"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="93"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="134"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="193"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="224"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="251"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="292"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="11"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ88251.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="321" mass="36607" checksum="A5FAC64E84D4B723" modified="2016-11-30" version="1">MSPGEYELPSIYTQSRGQNRPFQDSDDEDPLDTRSPMPSHKSSTIRQYKDIHVEDNRLAWLLLGTSLSILIMTVIPVLAKLPDFSVWFSGNTLWRLFDPLITLPLNLFVITRANIMLNGKSYYWGDLSEASVTWLFWAFGAGIYCQFHGIHAAAAMFKHPIQDFNLAHPELVLQYPVLEEMYSNMRDLWEHYIAHYLYVLGAMMMSWAQLFAFRNQLHGPLPTITRVVWCVGIVFYGLLLAGVAIEFPQGLYVGIGYTILMSFVCVAMIVFNRHNLDKGGLFTMGRRMVLQFYLSSCLLGLLVIVIWIGIFGFQNRKAAGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NGS9</accession>
    <name>A0A1C7NGS9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">HIT-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_03628</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000160">
        <property type="protein sequence ID" value="OBZ88322.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NGS9"/>
    <dbReference type="STRING" id="101091.A0A1C7NGS9"/>
    <dbReference type="InParanoid" id="A0A1C7NGS9"/>
    <dbReference type="OrthoDB" id="18412at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="26"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="26"/>
            <end position="35"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ88322.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="125" mass="14523" checksum="E1989AC323ABFB15" modified="2016-11-30" version="1">MPKVCSLVCFKQHKEIPCEQIITEDKSVHTSRKEITPIGPPDEEDPSRLTPEDLAKLSYSKEVLEYLQDSQLREVITKIDASETPEKDLDRVRAEYPKFDEFTKLLVDITFKQKLESIQQKKNNT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NH77</accession>
    <name>A0A1C7NH77_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">CID domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">A0J61_03832</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000174">
        <property type="protein sequence ID" value="OBZ88109.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NH77"/>
    <dbReference type="STRING" id="101091.A0A1C7NH77"/>
    <dbReference type="InParanoid" id="A0A1C7NH77"/>
    <dbReference type="OrthoDB" id="21470at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048471">
        <property type="term" value="C:perinuclear region of cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006874">
        <property type="term" value="P:intracellular calcium ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.60.10">
        <property type="entry name" value="Zinc finger, CCHC-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006569">
        <property type="entry name" value="CID_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056721">
        <property type="entry name" value="DUF7819"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008942">
        <property type="entry name" value="ENTH_VHS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001878">
        <property type="entry name" value="Znf_CCHC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036875">
        <property type="entry name" value="Znf_CCHC_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12323:SF0">
        <property type="entry name" value="CALCIUM HOMEOSTASIS ENDOPLASMIC RETICULUM PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12323">
        <property type="entry name" value="SR-RELATED CTD ASSOCIATED FACTOR 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04818">
        <property type="entry name" value="CID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25127">
        <property type="entry name" value="DUF7819"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00098">
        <property type="entry name" value="zf-CCHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00582">
        <property type="entry name" value="RPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00343">
        <property type="entry name" value="ZnF_C2HC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57756">
        <property type="entry name" value="Retrovirus zinc finger-like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51391">
        <property type="entry name" value="CID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50158">
        <property type="entry name" value="ZF_CCHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="CID" evidence="4">
        <location>
            <begin position="25"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="domain" description="CCHC-type" evidence="3">
        <location>
            <begin position="494"/>
            <end position="507"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="171"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="304"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="173"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="311"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="335"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="350"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="388"/>
            <end position="408"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51391"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OBZ88109.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="510" mass="58858" checksum="94084831D30CF4F7" modified="2016-11-30" version="1">MQDLPLPAYFQQLCQHMLDGSSRNTTKKSVEDFRVILHLIMHECSKANIETGKSWVFEHCHQPHHIVAVLEYMLALSKSRNSPTDRLHVIYLLNDVVFHTKQLLWMRDAMLPLLVPMLRLAYEAAGSPEYEAKIMKTVGFWGEKHIFEPQVIQQIRHDITSQPFYNSFQTYQPSPPPPPPPNRMAPMFVPSAPPSSTPPVMHTPLPPPPPKPYHELPAGLMLLVKVSTIYTEDYQPMDPNQIRVPPRPPPTKELMAAVDEFYQGLDLKTVDDIIVDEQAASSHIDPQGWEKNYLDDYTAMIHQQKQARLRASSERSESADYQRGRSGSSRRHYHRDSYSPRSRSYDRSRSRSRSRSRSRSRSRSRSRSRSRSPYYHRQRGRSPSSRGYQRRSFSRSRSRSRSRSRSRSRSPSPNLLQQGFSHHPMSSSSSSSARPNHSGYTSKPLGRNDNRLGGTNENRYTGLGTKSMMDEFDHFRRNKSQAFSKREPHQPFTCYRCNKVGHLARECNSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NHN8</accession>
    <name>A0A1C7NHN8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Kinesin-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">kif11_1</name>
        <name evidence="10" type="ORF">A0J61_03305</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="5 6">Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000139">
        <property type="protein sequence ID" value="OBZ88652.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NHN8"/>
    <dbReference type="STRING" id="101091.A0A1C7NHN8"/>
    <dbReference type="InParanoid" id="A0A1C7NHN8"/>
    <dbReference type="OrthoDB" id="3176171at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008017">
        <property type="term" value="F:microtubule binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003777">
        <property type="term" value="F:microtubule motor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007018">
        <property type="term" value="P:microtubule-based movement"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000278">
        <property type="term" value="P:mitotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.850.10">
        <property type="entry name" value="Kinesin motor domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027640">
        <property type="entry name" value="Kinesin-like_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019821">
        <property type="entry name" value="Kinesin_motor_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001752">
        <property type="entry name" value="Kinesin_motor_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036961">
        <property type="entry name" value="Kinesin_motor_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47968">
        <property type="entry name" value="CENTROMERE PROTEIN E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47968:SF75">
        <property type="entry name" value="CENTROMERE-ASSOCIATED PROTEIN E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00225">
        <property type="entry name" value="Kinesin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00380">
        <property type="entry name" value="KINESINHEAVY"/>
    </dbReference>
    <dbReference type="SMART" id="SM00129">
        <property type="entry name" value="KISc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00411">
        <property type="entry name" value="KINESIN_MOTOR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50067">
        <property type="entry name" value="KINESIN_MOTOR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-0493">Microtubule</keyword>
    <keyword evidence="4 5 6" id="KW-0505">Motor protein</keyword>
    <keyword evidence="1 5 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Kinesin motor" evidence="9">
        <location>
            <begin position="21"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="381"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="490"/>
            <end position="554"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="99"/>
            <end position="106"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00283"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000394"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50067"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OBZ88652.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="569" mass="64853" checksum="4B731CBD71B97C4A" modified="2016-11-30" version="1">MITTSSTSARRRTMSHTKEENVQVTVRCRPPARNEQANCWDIEPTKISLKEEVRYRTPQEFMFDHVLYGSDNALMYDTTVRNLINQVMEGYNGTVFAYGQTASGKTFNQFSPKMVFDNLFSPLPYFIDRWVTNQNQAITREFLLRVSYLEIYNETIKDLLNPSNDNLKIHQDKVRGVFVSPLTEEVVTTPDDVLRIIERGEANRHISSTDFNLHSSRSHTMFQMIIESRERSSTSTQLSNYKRTLTSSGFGGMSKSKELVKISQLNLIDLAGSEKAASNEDRRKEGSYINKSLLTLGTVISKLTESSNGKFPTHIPFRDSKLTRILQTALTGQAKVAVICAISPSISSIEESINTLKFASRVKRITIHAKNDAVMDDKALLQKYQSEIIELKSKLQSTADILEQEKQKTESAIMAERMDHEQQMQRMQAIRNVMKERIDHLTRLILTSSSVVMTDVTADMLTSDDTMGISLPPSPPMSEQNSTLLQHSHSQNDKAVIQELRRQIGKMEQESREKDHRILALEEQLRHATATVSKLETKLSIQRAELEINELLAKEQYNQRPSFGFEEIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NHZ4</accession>
    <name>A0A1C7NHZ4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">ER membrane protein complex subunit 2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">EMC2</name>
        <name evidence="5" type="ORF">A0J61_03315</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Part of the endoplasmic reticulum membrane protein complex (EMC) that enables the energy-independent insertion into endoplasmic reticulum membranes of newly synthesized membrane proteins.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Component of the ER membrane protein complex (EMC).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Endoplasmic reticulum membrane</location>
            <topology evidence="3">Peripheral membrane protein</topology>
            <orientation evidence="3">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the EMC2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000140">
        <property type="protein sequence ID" value="OBZ88638.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NHZ4"/>
    <dbReference type="FunCoup" id="A0A1C7NHZ4">
        <property type="interactions" value="257"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NHZ4"/>
    <dbReference type="InParanoid" id="A0A1C7NHZ4"/>
    <dbReference type="OrthoDB" id="124397at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072546">
        <property type="term" value="C:EMC complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039856">
        <property type="entry name" value="EMC2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055217">
        <property type="entry name" value="TPR_EMC2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12760">
        <property type="entry name" value="TETRATRICOPEPTIDE REPEAT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22890">
        <property type="entry name" value="TPR_EMC2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0802">TPR repeat</keyword>
    <feature type="domain" description="EMC2 TPR-like" evidence="4">
        <location>
            <begin position="87"/>
            <end position="195"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU367091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF22890"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OBZ88638.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="229" mass="26893" checksum="A23D25EF5E13C9BD" modified="2016-11-30" version="1">MPSFNYTQAVEELQQYRLTKQRSSERVAHLGAKIIKGNYTSKLGDQVWPFYEQIAIAALDVQDDDLANLCMDRLRERFTEKSLRFRRLIGMQYEAQGKLDEAQEIYDTILKEDDTNMLASKRQIALLRARNKENELVEALTKYLDTYSDDYESWLELCDFYLSKHMYDQASFCCEELILLQPGNPIFYLKYAEVLYTLNQLPLALKHYCKVLELCEDHVRALYGLHLVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NI98</accession>
    <name>A0A1C7NI98_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_03087</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000127">
        <property type="protein sequence ID" value="OBZ88863.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NI98"/>
    <dbReference type="InParanoid" id="A0A1C7NI98"/>
    <dbReference type="OrthoDB" id="2283974at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="176"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ88863.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="204" mass="23882" checksum="1F2AB77B024EA1E6" modified="2016-11-30" version="1">MITTRYNPDSHLYHSHNNTATKRGHDVSYHRFTLDEKNKNWTDESGDEQQFLRHDKDKFIELAQAALEEAKMEEEQKGVFQELLETFLARSGAPVVADVILEQFRSQDVIERLAEDHFEQQQERRRSSCLENDEISQVLKDPASEQVTMHSEAILTTTNQNNFDTIMLVSEYLWRFFRLLILASLVCLVYHFICTDPNQSLTKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NIC1</accession>
    <name>A0A1C7NIC1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">VWFA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">A0J61_04851</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000247">
        <property type="protein sequence ID" value="OBZ87094.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NIC1"/>
    <dbReference type="InParanoid" id="A0A1C7NIC1"/>
    <dbReference type="OrthoDB" id="1149618at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.410">
        <property type="entry name" value="von Willebrand factor, type A domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058580">
        <property type="entry name" value="DUF2828"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056690">
        <property type="entry name" value="DUF7788"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011205">
        <property type="entry name" value="UCP015417_vWA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036465">
        <property type="entry name" value="vWFA_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31373">
        <property type="entry name" value="OS06G0652100 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31373:SF27">
        <property type="entry name" value="TROVE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11443">
        <property type="entry name" value="DUF2828"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25043">
        <property type="entry name" value="DUF7788"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF015417">
        <property type="entry name" value="T31B5_30_vWA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF2828" evidence="2">
        <location>
            <begin position="64"/>
            <end position="531"/>
        </location>
    </feature>
    <feature type="domain" description="DUF7788" evidence="3">
        <location>
            <begin position="548"/>
            <end position="776"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="252"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="741"/>
            <end position="767"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="741"/>
            <end position="757"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="758"/>
            <end position="767"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF11443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF25043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OBZ87094.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="788" mass="90819" checksum="80B83999436575CD" modified="2016-11-30" version="1">MSSFATYPASLPFFKDLHDEELLGKLILELGQDKLVNDTSKLDISERKHPFMDAYEKKANETLTTNGGLTNASTLDPIIDLFYGYDTVKTEGRNQMYEAAWKADPMMTLRIIFYGRSIHRGKSLTSAFYTAFCWLLINHPRTALANLHMLIDGKVRTDAQLQYNRVKKAKKVRAEKQGWDMVDEEDNYKLLDRRDYKTHGYWKDLCSILTIYAQGELEGHKNSEYLALAWPRMEHDRQAHKEKKAEIKRLYEERKNMSPEGKAKYREEADRKTREKNETKKAKAKEDRYKTRAERNERSQLLLKNDKKYRALHFTIARLFAKQLKADIEQLETNKKMLEEGKLSGRHALGFNLSLAAKWAPSLGNSHDKHTFLATSIAEVLFPPETYQDKEETREHYLNEARDRYRKQYLIPLRNALDLIDHYKQPGHWEQVDISHMPSKCLQKELGLFFRHAPETVMKYMDELSQGKRKVSGATLGPHELVHRFRTRDIDDNLRSLLQQNAELYEKFSSMKATTINAQWDTLIKSIRETSLLNCDDSKKSKKVDLGDCLAICDVSGSMFSGNDPKYPEMAPFNAAIGLSLVITNLAKPPFNGAIITFSAEPEMFKVNTSAKFTDQVEEVMACDAGFNTDLAKVFTDVLLPMAKEHKIKPEDMVKRLFIFTDMNFDACDNGGDKLMKTHDFICKQYQDSGYEVPEIVWWNLCSAKEYMSPKKMNTPIDKDDLGITLLSGFSSAMIKAFFDGEAEEEEDEEENEEGDENESKQKEKKGPMDFIRKSVCHESFDGLVIID</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NIF0</accession>
    <name>A0A1C7NIF0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_03081</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000126">
        <property type="protein sequence ID" value="OBZ88881.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NIF0"/>
    <dbReference type="InParanoid" id="A0A1C7NIF0"/>
    <dbReference type="OrthoDB" id="2275837at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008889715" evidence="1">
        <location>
            <begin position="21"/>
            <end position="294"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ88881.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="294" mass="34523" checksum="33AF07466F7ED235" modified="2016-11-30" version="1">MTNFLIYLLSFIGIIPITEQESDNTHYRQSRRTRRSEEACLHLDSSDFVVSSLMVHEAEFDEKKSLMVDDFQTWISRLSRMTLCQILTSTINEHPNVGDEICNRHYKKAYSATKSNRPMLPKEEEQEVLVIIQQKARNISHQLDNLRPSEQFGKAHHVYNQLQALVRSLPIHDHDSFATLFSLIVLAQESLSAPSEVRQHLFYDAKLGRVLILELASLLKNFRPSFKKNSHSSTSMDQYYWSHVLKQEQNWLFCLEDICSKLSRYDATWEYRNEYQDVLIIAERYHKSSYLSIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NIM6</accession>
    <name>A0A1C7NIM6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="2">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">hhp1_1</name>
        <name evidence="13" type="ORF">A0J61_03294</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein kinase superfamily. CK1 Ser/Thr protein kinase family. Casein kinase I subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="2"/>
    <dbReference type="EMBL" id="LUGH01000139">
        <property type="protein sequence ID" value="OBZ88659.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NIM6"/>
    <dbReference type="STRING" id="101091.A0A1C7NIM6"/>
    <dbReference type="InParanoid" id="A0A1C7NIM6"/>
    <dbReference type="OrthoDB" id="5800476at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd14125">
        <property type="entry name" value="STKc_CK1_delta_epsilon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000159">
        <property type="entry name" value="Casein kinase I hhp1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000538">
        <property type="entry name" value="Putative Casein kinase I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050235">
        <property type="entry name" value="CK1_Ser-Thr_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11909">
        <property type="entry name" value="CASEIN KINASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 13" id="KW-0418">Kinase</keyword>
    <keyword evidence="5 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="12">
        <location>
            <begin position="15"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="322"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="385"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="489"/>
            <end position="586"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="355"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="396"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="11">
        <location>
            <begin position="425"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="497"/>
            <end position="509"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="522"/>
            <end position="531"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="555"/>
            <end position="568"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="569"/>
            <end position="586"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="44"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="OBZ88659.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="586" mass="66558" checksum="773EB64AC2C98C84" modified="2016-11-30" version="1">MSTLEGREIIIGTKYKLGRKIGAGSFGEIYLGTNIMSGEDIAVKLESIRAAHPQLEYEARVYKTLAGGVGIPFVRWYGREGDFNVLVMDLLGPSMEDLFNYCKRRFSLKTVLLLADQLLSRVEYVHSKGFIHRDIKPDNFLMGIGKRGNQVNMIDFGLAKRFRDPKSNVHIPYRENKNLTGTPRYASVNTHLGIEQSRRDDLESLGYILVYFCRGQLPWQGIRARTKKEKYDKIMEKKMTTPADALCRGLHQEFAIYLNYVRSLRFDDKPDYSYLRKLFRDLFVREGFQYDYVFDWTIRKLQEKKATSYQQESNMNPMYMSNAPFDVNSRRMPSAMPTNGNSGAPLPSANLRTTYHTDRKSPETSKRLDDVMLQYQQQQKILQHKSPGYFSGGNSPTTLQPIQQQQQQQSPTFQDPYVPQLGYPSSGGGAGGGGGGRMLVRDNQPPPPSSSSQQQQHQLGGKYERKRVLADEPNPIEPSIADPLFSVKRTHFHPHTGPSSSRVLRSQTKAGLGSPHQPQPYTTFHPDTTTTNSPSNNHAFLPDPNDNGDMNYARKPTDIHALMDERKPSQSSKPFHLSNTRLFEDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NIR9</accession>
    <name>A0A1C7NIR9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_03052</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000125">
        <property type="protein sequence ID" value="OBZ88898.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NIR9"/>
    <dbReference type="InParanoid" id="A0A1C7NIR9"/>
    <dbReference type="OrthoDB" id="2284905at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="39"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="47"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ88898.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="143" mass="16746" checksum="E3F334D5CB435B6F" modified="2016-11-30" version="1">MAAATEKFIRNHTTDMIHSEDLTASQFAYLTGIQTKRHPIESPMIESDSDSDSESELEEDHLYSASIMTHHSQQDIRIWDTRFWQYEPKQLTRHQSEPGVRPNVIQKGRFRIMWGSMDDDLTAHSQPAIRCIEWKRKRSQSQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NIS9</accession>
    <name>A0A1C7NIS9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Pentatricopeptide repeat-containing protein-mitochondrial domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">A0J61_03034</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Regulates mitochondrial small subunit maturation by controlling 15S rRNA 5'-end processing. Localizes to the 5' precursor of the 15S rRNA in a position that is subsequently occupied by mS47 in the mature yeast mtSSU. Uses structure and sequence-specific RNA recognition, binding to a single-stranded region of the precursor and specifically recognizing bases -6 to -1. The exchange of Ccm1 for mS47 is coupled to the irreversible removal of precursor rRNA that is accompanied by conformational changes of the mitoribosomal proteins uS5m and mS26. These conformational changes signal completion of 5'-end rRNA processing through protection of the mature 5'-end of the 15S rRNA and stabilization of mS47. The removal of the 5' precursor together with the dissociation of Ccm1 may be catalyzed by the 5'-3' exoribonuclease Pet127. Involved in the specific removal of group I introns in mitochondrial encoded transcripts.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Binds to mitochondrial small subunit 15S rRNA.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the CCM1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000124">
        <property type="protein sequence ID" value="OBZ88908.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NIS9"/>
    <dbReference type="STRING" id="101091.A0A1C7NIS9"/>
    <dbReference type="InParanoid" id="A0A1C7NIS9"/>
    <dbReference type="OrthoDB" id="185373at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002885">
        <property type="entry name" value="PPR_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057027">
        <property type="entry name" value="TPR_mt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47447">
        <property type="entry name" value="OS03G0856100 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47447:SF17">
        <property type="entry name" value="OS12G0638900 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13812">
        <property type="entry name" value="PPR_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23276">
        <property type="entry name" value="TPR_24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51375">
        <property type="entry name" value="PPR"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="PPR" evidence="5">
        <location>
            <begin position="73"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="domain" description="Pentatricopeptide repeat-containing protein-mitochondrial" evidence="6">
        <location>
            <begin position="250"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="repeat" description="PPR" evidence="5">
        <location>
            <begin position="284"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="repeat" description="PPR" evidence="5">
        <location>
            <begin position="356"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="repeat" description="PPR" evidence="5">
        <location>
            <begin position="391"/>
            <end position="425"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00044493"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00044511"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00708"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF23276"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OBZ88908.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="515" mass="58500" checksum="7B1377BA9F7EE62B" modified="2016-11-30" version="1">MLLRSLNLSTKRLYGLTQSCRYYTSENALLTDINKKMFDVINRAASANLGSQITLRRILQLADELRQNNVKFDHKTYEHILSAYAKAKQPNKILMLQKQMDGNNVKPSREFYQKALMLAACEGDSVLQSKIIHHMEQTGYPKTTKIYFLLILCMRETLEFERALDTFDQMKREKVPVSLSIYSVLFDMAISLKDPASACQMLKEAEQLKEFDQAKSKFSYMELLRLAALCDDINVIRAIWDKAEGLRPDEGLLLYVLNLASKHGDTKLATNAMKLIGEQGFVYKECHFAPLIETFAATGEVSNAFQLFTAMRKVGVTPTRQSAMPLVRRLGQDKNAVLRAKQVLLEQHTAQQGKIDVVALNLVIHALAYNKENEEALELYEQSKSMDVIPNSETLDAVLDACIHTKNTELGTKVYKEFLEDGIRPTANSLSKMVALMCTQEEDFEGAFMYLEEMKKLELVPLQGCYYKLVKLLSRTHDPRLEMALDDMKAYGYSISNHLIEYVERGKMIAAAATE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NIV3</accession>
    <name>A0A1C7NIV3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Meiotically up-regulated gene 89 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">mug89_2</name>
        <name evidence="8" type="ORF">A0J61_02982</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the CDC50/LEM3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000121">
        <property type="protein sequence ID" value="OBZ88965.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NIV3"/>
    <dbReference type="FunCoup" id="A0A1C7NIV3">
        <property type="interactions" value="307"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NIV3"/>
    <dbReference type="InParanoid" id="A0A1C7NIV3"/>
    <dbReference type="OrthoDB" id="340608at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045332">
        <property type="term" value="P:phospholipid translocation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005045">
        <property type="entry name" value="CDC50/LEM3_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10926:SF0">
        <property type="entry name" value="CDC50, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10926">
        <property type="entry name" value="CELL CYCLE CONTROL PROTEIN 50"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03381">
        <property type="entry name" value="CDC50"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF015840">
        <property type="entry name" value="DUF284_TM_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="39"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="342"/>
            <end position="363"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009457"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRNR" id="PIRNR015840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OBZ88965.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="398" mass="45553" checksum="8382756B97E1776D" modified="2016-11-30" version="1">MTKKEENEDQAKKTRKPADGAFRQQRLPAWQPVLTPRTVLPTLFIVGILFCPAGGLLWWNSNRVDQIMINYSYCQDYDAPVYMTSSLYDYQISDSNFDASSMQPPAYHYSNASSFLDTAWGNPNNLQIPRCAIDFTIPSTMKAPVYMYYRLTNFYQNHRQYIKNFDDTQLSGDIQSTSVLHTNCDPLAVNSEGKVIYPCGLIANSMFNDTISNFTSLEQQGNSYNFSRNNIAWPTDKQKYRPTKYQISQIAPPPNWAQRYPNGQYTEQYPPPDLSTQERFMVWMHVAALPDFRKIWGRNDAVALPAGRYRAYIDMNFNTRQYGGEKWLVLSTTTGMGGRNPYLGIAYMAIGALCIFLGLLFTIRHCIKPRKLGDESYLSWNQPGGGLPSSKRNHLHKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NJ79</accession>
    <name>A0A1C7NJ79_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Ankyrin repeat and KH domain-containing protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">ANKHD1</name>
        <name evidence="11" type="ORF">A0J61_02838</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000113">
        <property type="protein sequence ID" value="OBZ89115.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NJ79"/>
    <dbReference type="STRING" id="101091.A0A1C7NJ79"/>
    <dbReference type="InParanoid" id="A0A1C7NJ79"/>
    <dbReference type="OrthoDB" id="660555at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd15737">
        <property type="entry name" value="FYVE2_Vac1p_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000306">
        <property type="entry name" value="Znf_FYVE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017455">
        <property type="entry name" value="Znf_FYVE-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24171">
        <property type="entry name" value="ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 39-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00023">
        <property type="entry name" value="Ank"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13857">
        <property type="entry name" value="Ank_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01363">
        <property type="entry name" value="FYVE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00064">
        <property type="entry name" value="FYVE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50178">
        <property type="entry name" value="ZF_FYVE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 7" id="KW-0863">Zinc-finger</keyword>
    <feature type="repeat" description="ANK" evidence="6">
        <location>
            <begin position="120"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="6">
        <location>
            <begin position="153"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="domain" description="FYVE-type" evidence="10">
        <location>
            <begin position="599"/>
            <end position="674"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="316"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="549"/>
            <end position="569"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="463"/>
            <end position="513"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50178"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="OBZ89115.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="679" mass="76515" checksum="843843A6B43EFCFE" modified="2016-11-30" version="1">MATVIDFCTPAVPGEVHKYYGDSHNKFLKLPHIPPASQTPKKVANKKSELKTLRSVALYGDLRLLRHFLEMVPDKIKAVNEPHPATGLTCLHFAASQGHLKFIQCLVEEYAVRVDSTDKEGETALLKAAYNGHYHVVEYLLNSNANIHHKDKDGWTALHNACSRGYIRIVRLLIERKAKVEARSKMGHTPLINAASKGYMTIVEYLLDEAHANPLIKNNFGEAAYDVSAAAGESYICEMLEKAGRKWWHLQHTEGILNPGNKRASRFGAVYDLLDFHVTAIVILHENQRSSSLLGFYRPQFSATYLTAADTRGPWSLHPSGEPSSKEAVALPSNASNNHRDSKLSNWFWLTDWQVDYSNPRVDPTSGWQYARSFADDDSAWTPVAPTSGYNWVRRRRWVRVMKRKVDLEKGSYRGEHMPIANDIDEEDETDSQEDTNDYLLEAENIIQSVKSDMNTEQDTHDAEVLRDDIQKYNKAIDLLMEAISTDDNEFRMNQATTLIRSYSSQIDKLNAKITESGASAITSITSTITATTVDTDIASPTNLKLDLDTADDDNPWSNSSSSNRENLTVNWTGSPQNLSSIDILVPEEQKPTRVWESDVSAKACRICVKKFSFLLRRHHCRKCGMVVCDKCSPYKVFLNPSDILQDPNGVLESVSVLAVQKQRICERCYFQENMIPGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NK21</accession>
    <name>A0A1C7NK21_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Chromo domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">A0J61_03110</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000128">
        <property type="protein sequence ID" value="OBZ88836.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NK21"/>
    <dbReference type="STRING" id="101091.A0A1C7NK21"/>
    <dbReference type="InParanoid" id="A0A1C7NK21"/>
    <dbReference type="OrthoDB" id="5376140at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="CDD" id="cd00024">
        <property type="entry name" value="CD_CSD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016197">
        <property type="entry name" value="Chromo-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000953">
        <property type="entry name" value="Chromo/chromo_shadow_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023780">
        <property type="entry name" value="Chromo_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023779">
        <property type="entry name" value="Chromodomain_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00385">
        <property type="entry name" value="Chromo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00298">
        <property type="entry name" value="CHROMO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54160">
        <property type="entry name" value="Chromo domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00598">
        <property type="entry name" value="CHROMO_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50013">
        <property type="entry name" value="CHROMO_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Chromo" evidence="4">
        <location>
            <begin position="36"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="87"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="405"/>
            <end position="520"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="95"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="131"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="154"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="177"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="226"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="266"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="276"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="405"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="462"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="478"/>
            <end position="490"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="491"/>
            <end position="500"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50013"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OBZ88836.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="968" mass="109790" checksum="E1E45602EA0C26A7" modified="2016-11-30" version="1">MTIDVNKKEEKKPDAGTANTMTVAEEFDDDDVDFYYEVEEIVQMYITETGVRMFEIKWKNYDSSSNTWEPEYNLNCPTILEDFLKKHNQKKKNQAELSQAEPNEAESSQTKSKLNKGKRPDKEEEEEENKKGKRKKRSKDRKQKELEEEMEYLDEMKEERRKLDEAKRKRTSAGLLSDRKKDLFERKQEYQAKRKERNSKKAKLPDENDQQKDEEEEGSPAKKKKKENDKEEGKEKKESGDAIKRQKPDSPPRQPGKRGRPPSKPTASVHTANVATSSAKTTTETTSVSVNSNTKTTTVTSNKLPLSSANFKPHSGVPMEKKQLAISKAHEYKPSFTNIKRPMTTNPSTSNVDIAALLLQSVGSPSKLPNIPKYGPNTRPAPIQRQEPITNTNIPTTSSAAVATTTTTAATVTAPPLPPSSSVSTVPQSSTIKSPVITPHPLPSSTTPTSPSPASPNRSPVIKQTSNFITESATSIHSPSVSPPQVFQTPPSSPPPPNQSSPPRVTQPEASIRSTEPHSLIAPLNQQRTMIVSPKRTDPRLVVDNMRKLKIQNSTALPTPFSRSCILLKGEKMISSIELEGKQRCYHQPKIEQLIEKSEQGHVVRISSFLSLKRLDDVLLEHPFSYLQITAKDQLIELSKFKSFLQVNEVVGVVSHDQLPTCALVILPEGEAKKLKNLPQEQDMVVSKYTQLCGIFVDFLPPKPRSLFDHLDIPEDEFNWLRVAQYLMFTPKLIELRTTSKFLVYGQSEAAHLLTKINENQEYRKTTDKPTYIMMFDRYRQTAFSRNLLKHKKEPSTEIWEFGVPDFSCPEMMPPSPIFPINTGGFVTTDIQNIIQQPDIFEKLLQTVNKFNSVPVVYGEWKLIIPHNFMYHFTRAIRDGETATKVQNAMIAITVGLSKGDVQIMRLWPAEKESMDTVDYMDKIMRYYYRSYQYFVIVDDIGSISTETRDEYRALDFVKSQDLFSTFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NKI1</accession>
    <name>A0A1C7NKI1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein YbeQ</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">ybeQ_5</name>
        <name evidence="2" type="ORF">A0J61_02631</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the sel-1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000101">
        <property type="protein sequence ID" value="OBZ89319.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NKI1"/>
    <dbReference type="STRING" id="101091.A0A1C7NKI1"/>
    <dbReference type="InParanoid" id="A0A1C7NKI1"/>
    <dbReference type="OrthoDB" id="2253126at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006597">
        <property type="entry name" value="Sel1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050767">
        <property type="entry name" value="Sel1_AlgK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11102:SF160">
        <property type="entry name" value="ERAD-ASSOCIATED E3 UBIQUITIN-PROTEIN LIGASE COMPONENT HRD3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11102">
        <property type="entry name" value="SEL-1-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08238">
        <property type="entry name" value="Sel1"/>
        <property type="match status" value="9"/>
    </dbReference>
    <dbReference type="SMART" id="SM00671">
        <property type="entry name" value="SEL1"/>
        <property type="match status" value="9"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81901">
        <property type="entry name" value="HCP-like"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00038101"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ89319.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="470" mass="53855" checksum="33E8A99DA6B0AAF4" modified="2016-11-30" version="1">MNTVSETEKIEFLYQEGIRLYNKQHYTDAFYCFENAANLDHSPSMIKIGRMYELGEGVALDYQEALYWYRKAAYLGFSGGELCLGVFYEEGKGIKKNISIASKWYQKAASQGSIEAAFKLGCLYYRGAGVPEDKQMALRLFIEGANRDYARAAFMAARIYCSLSKHDPAYRTQALHWYTYAAERNYPRAQYNLGCFYEMGVPPVLQQDDVLAFRWYEKAAKNGHADAQSSLGHCYFNGIGITKDNGLSLFWYTRAIENGATVINNTKIKHKIASYKRRGSQSMLQDEYKDVNQAYLEGTDVRKDKTLVQIGDMFLSGTHVKKNHEKALEWYLKAAERDNPEGQFKLGKMYFEGLGTIKNYNISLGWFKKAYKHGVQDALAYIERAKLSLKTQKTYFQQVEQKPNLKEVILVDDYALRDFSTEVLDSLNEVYRNRIKSSIYALETSDADPIRSARNAFDAISIHNPNDYST</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NKI8</accession>
    <name>A0A1C7NKI8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_04158</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000197">
        <property type="protein sequence ID" value="OBZ87794.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NKI8"/>
    <dbReference type="InParanoid" id="A0A1C7NKI8"/>
    <dbReference type="OrthoDB" id="10593644at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd09917">
        <property type="entry name" value="F-box_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12937">
        <property type="entry name" value="F-box-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="1">
        <location>
            <begin position="4"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12937"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ87794.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="647" mass="74992" checksum="4E27B3F9B4D13E77" modified="2016-11-30" version="1">MRVDLPFDVHLIILSYLDKLDKHQYGLVCKQWYEPAKHAIFRVTSVTVEKKLDAFVDALATSNIGNYISELRLYMGHRTKGWSPSLMEKRKKQFAALIKHTPNLNLLEVGTSNPDKDENTSDRVAFFSGWRDKKEPEAPVEKGVNPFYQVVLESIRNGHWKALHSIDDDLLSENCKEDSEDSEGIEDYLTPYYNAIISAMQERISYVVLDVTTTPELPLMPQCFKSSVKISKDTQFPKVKHLGCYSSEKTTIQTIDDVLELCPAATQVSLSLNEFHKNQGELKKVKPNTLVTNLRVIVFSLTESFLNYMCRKFPNANKLDMIVLEGCTMKSVIEDEDEDDFAFDSDDDFDVGSRYWLEIPTKMIQQLATYVKSMERFLIRIHYVANRVEVFDIFNKTLSPIKLYTRLDGLTIGTEPKKTKSTLQLDPNVTNIKLTATTKAALNQLDELFFDLNNIEPTVLPSANYRQLLTHCKQLKELSFSTFILYDFPKQTLPVTHLTIHDCEVDRKLWKQFSRQMPQLTNMKILFDPNSEGMKERDDNVFKIDMPFTSFSRLEIEYMLVFTRHVLYLKVTRSGTTTYYCQYDEDDEEVEGPSKKLKEITKKEYQGCISNEEFGVVELICQDIKHLRVHCWDVNDGFEFEKEHQFN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NL49</accession>
    <name>A0A1C7NL49_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">5',5'''-P-1,P-4-tetraphosphate phosphorylase 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">APA2</name>
        <name evidence="5" type="ORF">A0J61_02099</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000075">
        <property type="protein sequence ID" value="OBZ89861.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NL49"/>
    <dbReference type="STRING" id="101091.A0A1C7NL49"/>
    <dbReference type="InParanoid" id="A0A1C7NL49"/>
    <dbReference type="OrthoDB" id="10267950at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003877">
        <property type="term" value="F:ATP:ADP adenylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009117">
        <property type="term" value="P:nucleotide metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.428.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009163">
        <property type="entry name" value="Ap4A_phos1/2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043171">
        <property type="entry name" value="Ap4A_phos1/2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045759">
        <property type="entry name" value="Ap4A_phos1/2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019200">
        <property type="entry name" value="ATP_adenylylTrfase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036265">
        <property type="entry name" value="HIT-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38420">
        <property type="entry name" value="AP-4-A PHOSPHORYLASE II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38420:SF1">
        <property type="entry name" value="PUTATIVE (AFU_ORTHOLOGUE AFUA_5G14690)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19327">
        <property type="entry name" value="Ap4A_phos_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09830">
        <property type="entry name" value="ATP_transf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000846">
        <property type="entry name" value="ATP_adenylyltr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54197">
        <property type="entry name" value="HIT-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ap4A phosphorylase 1/2 N-terminal" evidence="4">
        <location>
            <begin position="3"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="domain" description="ATP adenylyltransferase C-terminal" evidence="3">
        <location>
            <begin position="184"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="49"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="49"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="1">
        <location>
            <position position="148"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR000846-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF09830"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF19327"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OBZ89861.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="328" mass="37154" checksum="D37A97A05CBF3BF2" modified="2016-11-30" version="1">MMNLFQEVQTKFNAAKESGDLISFDSTQVVKESGGIKFTITLAPALAKKEENKKENQQKEEKPNPFLNPNPALVIQETEEHRLLLNKFAVIPNHLLIVTKEFHKQTEPLFPNDLYETYQALQGFGMSRPALAFFNCGNQSGASQGHKHVQVLPLEYSQSAQPPIKQLYDEIHDRHIGQIYAINKLPFVHVIMALDSNAVRQTSQNKEALSDYLGQMFFGILDAMFQQLRENSLPMDTSYNFLMTQEFMMLIPRRKEVATIEHNGKTFEFSINSLGFAGLMLCKTEEELAALEAQENLMDMLTQVGVAWDPQSAKYDAERQMAASTELA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NL51</accession>
    <name>A0A1C7NL51_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein C14C4.10c</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_03929</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000181">
        <property type="protein sequence ID" value="OBZ88024.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NL51"/>
    <dbReference type="STRING" id="101091.A0A1C7NL51"/>
    <dbReference type="InParanoid" id="A0A1C7NL51"/>
    <dbReference type="OrthoDB" id="77989at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010945">
        <property type="term" value="F:coenzyme A diphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.79.10">
        <property type="entry name" value="Nucleoside Triphosphate Pyrophosphohydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045121">
        <property type="entry name" value="CoAse"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015797">
        <property type="entry name" value="NUDIX_hydrolase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020084">
        <property type="entry name" value="NUDIX_hydrolase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000086">
        <property type="entry name" value="NUDIX_hydrolase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12992">
        <property type="entry name" value="NUDIX HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12992:SF44">
        <property type="entry name" value="NUDIX HYDROLASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00293">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55811">
        <property type="entry name" value="Nudix"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51462">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00893">
        <property type="entry name" value="NUDIX_BOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nudix hydrolase" evidence="2">
        <location>
            <begin position="52"/>
            <end position="200"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ88024.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="313" mass="36236" checksum="0E2917DEEFB606F2" modified="2016-11-30" version="1">MTSDNFKTFRDLVTNLSQHQPIHIPSPPKQKRRGAVAAILRWHCPSRIVSNEKIETIHDFLEQPWVNQSDGYAEILFMQRTARPGDRWSGHVAFVGGKNEPGETDQETVEREVREEIGVDLSDHSKFLLVGKLDEREITSLKDNALVMILIPFVYLQIVPDSPPFQLQTSEVASVQWVPLPFFLSENSYSCQLITEALPIVRKFNSKWLQKAIQVMTGSVQFPAVDLPTQQHFRLWGLTMGMTSDLVQFTQKKHLAFVQMTRKEPVYSRIDIKYLTRWITQLTLLLKNKTYVQPMKMSMLERCFVAFRIEKDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NLG7</accession>
    <name>A0A1C7NLG7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_01955</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000068">
        <property type="protein sequence ID" value="OBZ90011.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NLG7"/>
    <dbReference type="InParanoid" id="A0A1C7NLG7"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="15"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="52"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ90011.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="92" mass="10380" checksum="D16616286DC45EA1" modified="2016-11-30" version="1">MDIGNLPVYTKTTNKTRDPNSTTKKDAWDRIGDYEEAPASNTKNDDDEEEKEQVIVHKKETVSPEERKEADDAASIASELAVKESRKHQTTC</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NLJ4</accession>
    <name>A0A1C7NLJ4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">F-box protein pof6</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">pof6</name>
        <name evidence="3" type="ORF">A0J61_02220</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000080">
        <property type="protein sequence ID" value="OBZ89729.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NLJ4"/>
    <dbReference type="FunCoup" id="A0A1C7NLJ4">
        <property type="interactions" value="45"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NLJ4"/>
    <dbReference type="InParanoid" id="A0A1C7NLJ4"/>
    <dbReference type="OrthoDB" id="5554140at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000145">
        <property type="term" value="C:exocyst"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006887">
        <property type="term" value="P:exocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006893">
        <property type="term" value="P:Golgi to plasma membrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd09917">
        <property type="entry name" value="F-box_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009976">
        <property type="entry name" value="Sec10-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048627">
        <property type="entry name" value="Sec10_HB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12100:SF1">
        <property type="entry name" value="RECYCLIN-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12100">
        <property type="entry name" value="SEC10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12937">
        <property type="entry name" value="F-box-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07393">
        <property type="entry name" value="Sec10_HB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00256">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="2">
        <location>
            <begin position="34"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="478"/>
            <end position="525"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="18"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="482"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="505"/>
            <end position="525"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ89729.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="867" mass="98858" checksum="02A3D7C96FD9D98F" modified="2016-11-30" version="1">MSLLDDDSFSNSLLDSSHPVQPVQTSLPGTMERTRSGKSIPPDVLIRIFQYLPVPSLAKMATVSRRFKVLAYDDEIWDEKLDIMLKNDTGALAAMLNSEGPKGSLIDSQNTIFINSKPLNTLIPGMSTDPYHARARAKSTGQSKEYFKQLYTQLLPYYVDLRDGNKESTKVLHDFGGNPEECGKVINLLVGLGQCHVVDGWQEINEGVSALSQYFESASLHQFEVAYDNQNTKDMRTYANALIALNGGSTCMQTYMQKHPIFYDNPYKPEDNFAISPDDLTPFKKFMTLVSEELKQQSFIILDVFPQEMDAFYMFVDRVFEDVIAEFVSQLLGIAMQIDSHRYLRTMSTVLSSTEKMVKVLTSDEISKPIQHDRGINLLFKLFLPFLDDYLFEESHYAERITKKYIEEWNNRSLFNTDISARLTNQSRETFKKNYLTAFKKVLTLPVDLVSTAATTIVSPFQRASIVSGLSKSSSAAEKRGSITSVESVSTSQTTPPPTPKATSMNRVSSSSTISTEQPRSSFSRDVTGQLEFARQELDLLQNYLSLETSLQLIHINKESERRVQQFIDIGFPGRMKTDIQRTYEQIFVQLLKTLGHTHIQPGFQSASDRLASFKPSVDHLNEDVPPLTAFFELIHVADLIQQMIQLYYDEEITKHVDKHDFMNEVNKEKKSFERLLDDCVAQGMDRGIQVLLSQVEFILTTEQKKEDYNPPSDSMPDLKPTKACQDTIHCLKTNTAMLFGAADKSTMDLFFTEIGRRFFEILCKHLKLQTVNEMGGFRYISDMNAYYDFILTLRQKTITPYFLALKSLANLYIIESATDIKSLIHDLERYHGLMRVEDLFEFAACRNDWPVIKRVVQKDMTDCCIM</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NM60</accession>
    <name>A0A1C7NM60_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">DNA mismatch repair protein MutL</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">mutL</name>
        <name evidence="4" type="ORF">A0J61_01765</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the DNA mismatch repair MutL/HexB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000060">
        <property type="protein sequence ID" value="OBZ90177.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NM60"/>
    <dbReference type="STRING" id="101091.A0A1C7NM60"/>
    <dbReference type="InParanoid" id="A0A1C7NM60"/>
    <dbReference type="OrthoDB" id="429932at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032300">
        <property type="term" value="C:mismatch repair complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140664">
        <property type="term" value="F:ATP-dependent DNA damage sensor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006298">
        <property type="term" value="P:mismatch repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="entry name" value="Histidine kinase-like ATPase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1540.20">
        <property type="entry name" value="MutL, C-terminal domain, dimerisation subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014762">
        <property type="entry name" value="DNA_mismatch_repair_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038973">
        <property type="entry name" value="MutL/Mlh/Pms-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014790">
        <property type="entry name" value="MutL_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042120">
        <property type="entry name" value="MutL_C_dimsub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037198">
        <property type="entry name" value="MutL_C_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10073">
        <property type="entry name" value="DNA MISMATCH REPAIR PROTEIN MLH, PMS, MUTL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10073:SF47">
        <property type="entry name" value="DNA MISMATCH REPAIR PROTEIN MLH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00853">
        <property type="entry name" value="MutL_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF118116">
        <property type="entry name" value="DNA mismatch repair protein MutL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00058">
        <property type="entry name" value="DNA_MISMATCH_REPAIR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MutL C-terminal dimerisation" evidence="3">
        <location>
            <begin position="471"/>
            <end position="646"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="326"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="327"/>
            <end position="336"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OBZ90177.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="701" mass="80096" checksum="7C1C3AA114CBA76E" modified="2016-11-30" version="1">MRERVGSERIALDANASSIDVILDIERFSFQVNDNGCGIYELKKIGQRHVTSKCHTMSDLNQLKTFGFRGEALAAITNESMTQIISRHRSSKTTYEGFWRDGKIVGEISESIYTRKDHPGTTVIVRDLFYKLPVRRRQSANAYQNVATIESVRRLIINFAIYFHHVSFTLIDSNRNNTILSAKRSDTSLGIFRQFFGQEMTKMQEEDVSVSSYISTQGYPNKTHQFIYLNNYFVPATNELYKIVSDMFSSSQFSNVQRKECVSAKKGKTRLLQKFPIFFIKFTCPKWSSFEIFMYLEMLSEFSSYSCIESLLKQLVTQFLQHAGLRTSRDNTPRHSAEKHKKKKSSNTSSVYLAHTPSITSSASSMVSSRPLQQEMTSRKETNFVTWWDSDAQKLVYLDSGTGNTFSTLPNSHDEVCPNQIDRSHLKKTHVTQDSHEQGYNIPETHKHLFQSPALIVPTKLSKEDLQYIRVLGQVDKKYIAVILKNNSILMIDQHAADERIKLEGLLQADVSWQVSTLEPGISLQLDSLAEYQIITSERNLNCLKMWGIYVTNAANNSMVSRSRFFSDTGNSDGDIFKIFVTQIPNIILDRCISDHALLKEVICDHAYWMMEQRDEAVLSTTCPKGILEILKSKACRSAIMFNDSLSLEQCQALVDKLSKCNFPFQCAHGRPSVIPINLHNINSFIYHKPKRSINWNALTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NMI3</accession>
    <name>A0A1C7NMI3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_01599</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000053">
        <property type="protein sequence ID" value="OBZ90341.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NMI3"/>
    <dbReference type="InParanoid" id="A0A1C7NMI3"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="20"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="35"/>
            <end position="45"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ90341.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="75" mass="7966" checksum="48BD2AB90010CC5F" modified="2016-11-30" version="1">MSEPLSNSTHVPTNDTAYPTTEAMTTTSTSENANKQQENQSEQQPSMLRLRGGGGCLTNCLAAIGCCCICEECCC</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NMJ7</accession>
    <name>A0A1C7NMJ7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_01601</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000053">
        <property type="protein sequence ID" value="OBZ90352.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NMJ7"/>
    <dbReference type="InParanoid" id="A0A1C7NMJ7"/>
    <dbReference type="OrthoDB" id="2289025at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ90352.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="158" mass="18248" checksum="E9F69CE6463A367A" modified="2016-11-30" version="1">MQHLIQRTGFYQPVETLPRFVIEDEPQEKELITRYLQAALVLLFETIIKHILFGWISINDNDKVIMLRPDASINVVYGAVVEQRLGCDEIKSQYQALNHRLTGLDLIRVVRLAKAALDKYKAITTFAFTAVGNHANFYALHRAKSNIYTMKLNIFNWP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NMZ0</accession>
    <name>A0A1C7NMZ0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">RNase H type-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_01460</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000046">
        <property type="protein sequence ID" value="OBZ90512.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NMZ0"/>
    <dbReference type="InParanoid" id="A0A1C7NMZ0"/>
    <dbReference type="OrthoDB" id="2290035at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd09275">
        <property type="entry name" value="RNase_HI_RT_DIRS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="147"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="150"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="164"/>
            <end position="173"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ90512.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="327" mass="37098" checksum="5FD7423A021F762E" modified="2016-11-30" version="1">MVSAIGEGADRLRAAGRGTTEIYSELKYIFEEGGDEEALRETLEKVRRLAVYCLATGKELDKDAKKGLYSCTNSPEVTAFPIIPTQRHNLPIQVLGIWSECSTQSFFQTDEIRFGAIESKRNAIEERIASKAQLRILELQFQQRANEDQCTTEEDDQTDCESSPIDKRQRESEIMQMNSSSSRQDSINYFSFEGGIIESTVYPTRPSQKFKDPQVQLGDSLQVVKRQLERISMCQEPRVSIYVDASDTRWEIVSELIQTNGYWAKEEKETSINARELKTILFAVKLHAEKYKKSTIHIHTDNTTAPKYVKESGGTASALLQTLILET</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NNA0</accession>
    <name>A0A1C7NNA0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">V-type ATPase assembly factor PKR1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">PKR1</name>
        <name evidence="2" type="ORF">A0J61_01445</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000046">
        <property type="protein sequence ID" value="OBZ90488.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NNA0"/>
    <dbReference type="FunCoup" id="A0A1C7NNA0">
        <property type="interactions" value="52"/>
    </dbReference>
    <dbReference type="InParanoid" id="A0A1C7NNA0"/>
    <dbReference type="OrthoDB" id="9626941at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070072">
        <property type="term" value="P:vacuolar proton-transporting V-type ATPase complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013945">
        <property type="entry name" value="Pkr1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28251">
        <property type="entry name" value="V-TYPE ATPASE ASSEMBLY FACTOR PKR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28251:SF1">
        <property type="entry name" value="V-TYPE ATPASE ASSEMBLY FACTOR PKR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08636">
        <property type="entry name" value="Pkr1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="32"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="59"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ90488.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="92" mass="10407" checksum="3310B1407F4F5517" modified="2016-11-30" version="1">MAEQQNIEIETTGLAGDIVKSIMTPGYTANGVINIMFYTFYALFATLLFMIFMTGGNPHVIALLLLAICLFVSIRWFITEMEHAKRQQQKTD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NP19</accession>
    <name>A0A1C7NP19_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="1">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">CDC42BPA</name>
        <name evidence="14" type="ORF">A0J61_01077</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. COT1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="1"/>
    <dbReference type="EMBL" id="LUGH01000030">
        <property type="protein sequence ID" value="OBZ90873.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NP19"/>
    <dbReference type="STRING" id="101091.A0A1C7NP19"/>
    <dbReference type="InParanoid" id="A0A1C7NP19"/>
    <dbReference type="OrthoDB" id="3638488at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005856">
        <property type="term" value="C:cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031032">
        <property type="term" value="P:actomyosin structure organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000024">
        <property type="entry name" value="Probable serine/threonine-protein kinase cot-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000961">
        <property type="entry name" value="AGC-kinase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050839">
        <property type="entry name" value="Rho-assoc_Ser/Thr_Kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22988:SF71">
        <property type="entry name" value="CITRON RHO-INTERACTING KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22988">
        <property type="entry name" value="MYOTONIC DYSTROPHY S/T KINASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00133">
        <property type="entry name" value="S_TK_X"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51285">
        <property type="entry name" value="AGC_KINASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 14" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="12">
        <location>
            <begin position="62"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="domain" description="AGC-kinase C-terminal" evidence="13">
        <location>
            <begin position="331"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="440"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="669"/>
            <end position="706"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="669"/>
            <end position="690"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00038271"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="OBZ90873.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="903" mass="105907" checksum="1755333DD8515256" modified="2016-11-30" version="1">MSRKHIIRQLIDKDALIDALISLYHNATKCQPNDNLNKFIQLYKPVYYEIIQSKLSIKDFHIIHKDSFAEGAFGKVTIVKSKDNQIYAMKTSNKAKLIHQMDRSSPMEERLLLSIATDENDPWFPKLHASFQDRTNLYLVMEYAPGGDLQGLMERRSYAPFAEEEARFYCAELVLAIERVHQLGFMHRDIKPGNILIDKTGHIKLGDFGSCISIDTNDYLFMVGTMPYVSPEMCNSEGSNPLDGPAYGPEVDWWSVGIVLYELLYGDTPFIGTDIKIQMSLLDPKIEVQYNPNIEVSNEAQDLISRLLAKSKDKRLGLNGVAEIKSHPFFSSINWDSIRTTATPPFIPTISSPDDVTFFSTTKSEDGATKWKENDSMYSDSLEDELNDHEYPFIGYTHIHHGTHQHEDKDTKYQQEIDQLQERHLKERRKLEEEIQQLKSKLETDQTSKEQVPQRLNRLVQQDNKPPRLDERMIQLQKKEKQKLQDQMIRMKQDYEQQMKKAQQERASLQASFNRQLIEKEKLQAALELNHASSDFQETIEHQQSRLEQLERELEEKSALYEQTIQETTWSLEQKIQQTTEAYEHEMDQSRQRIADLEKEAQLSVKEKHDQATETDETDLSTLKRLEEKLEYEVEKTNKLRERFKQKLKDQYQDFKLLIQQARDESYQLRQQLEKQQEQEQMKTSSEKRKSLPKVPYHPQSPGEDKTIVNTMWKRDRESLKTVQQALEDSEGRLSYAKKQIMRLKKEVKYYQAHPTKANDYDYDEKHYDHAVKNKLDYVNYPKPTYLHSSKTHTSSEKPTVYHDYTGLESKSKFYKSLQCRSKPHSDRAQDILERIQQEKDFIQSTQKTLLARARLSRTRTDVDKELKVSLERSYYQLSMLETQLKGISHSPYLAEHTKINPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NPG8</accession>
    <name>A0A1C7NPG8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_00933</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000025">
        <property type="protein sequence ID" value="OBZ91001.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NPG8"/>
    <dbReference type="InParanoid" id="A0A1C7NPG8"/>
    <dbReference type="OrthoDB" id="2222370at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ91001.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="151" mass="16959" checksum="62376DB0AE4AB859" modified="2016-11-30" version="1">MIHDDKWNLLADCDEAIKVPPPSPQDASMLEAVFSNHLSAKIHAVVNSSHGIDTNTAHARTLERLLSCKKRRRFRSSIAKRPSRIPVLSSRICKNKATQQQDALTKAFERIHISKSKNCLNGFTTNLINKSKNNDISVKEALLQSLKDMEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NQ34</accession>
    <name>A0A1C7NQ34_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">CST complex subunit CTC1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">A0J61_00797</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Chromosome</location>
            <location evidence="2">Telomere</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the CTC1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000020">
        <property type="protein sequence ID" value="OBZ91158.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NQ34"/>
    <dbReference type="InParanoid" id="A0A1C7NQ34"/>
    <dbReference type="OrthoDB" id="2314520at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990879">
        <property type="term" value="C:CST complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042162">
        <property type="term" value="F:telomeric DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045740">
        <property type="term" value="P:positive regulation of DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010833">
        <property type="term" value="P:telomere maintenance via telomere lengthening"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029156">
        <property type="entry name" value="CTC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042617">
        <property type="entry name" value="CTC1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14865">
        <property type="entry name" value="CST COMPLEX SUBUNIT CTC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14865:SF2">
        <property type="entry name" value="CST COMPLEX SUBUNIT CTC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15489">
        <property type="entry name" value="CTC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0158">Chromosome</keyword>
    <keyword evidence="7" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0779">Telomere</keyword>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="919"/>
            <end position="939"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="922"/>
            <end position="938"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006332"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00016175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022895"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OBZ91158.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="1160" mass="132861" checksum="54C98E932F54F9C4" modified="2016-11-30" version="1">MSLITVNDLLEWHESTSQEWTESDLLGILYIVMIDAEYPRGTILLKDVTTGTCFPCQINYFHPRLHQATILIKQWHFLHHEELAWIEFSTTNAYFMNHQTQSALEECLTIDNVLLEIASRTAVFVEPQDDLKEVVHLIGKVQSISALNALQSDQPAMFMIQLTNREETHKVCLIFEGDDCIPYYPMFHINFLCAFQHLSYSPEHDTLLFRSGKSACQIIHQHQLDQLIIPHGLSIPSLKKNMSLSGTITRVLDTMFGLYEVDHRILLCLYHSPKYSPARPLRVQTRIRLYHIHMVSIQQKEEDEESFQSCLLTHLLQAPLSHDTLNHYLCLVGCAHTDLEILSFPSHCDLVSLTTSVLSDPLKRHVYLDCLSGQVSFRQLICRLEIYATLIHFFSDQPAHHLKEAYDRLVQQKAATTSTITNDWKTQFLCHHHQKCTSTGLSPPFKQKQLEVVTIETYASLSHLMAYHQHHQNRPTSHTVPLSGASDRFEIDHVYTETMAFIPKDLSVLAQLGISPDGRLYVLLNDNTLPRILLLPPPTKPQQTISNGLYLIRRAQWIREDLSYLKVLEDGTKGSRQKLWHEYLACPEEGDLILLSPETPLAFDITEPNLFGPMVCSEDMHLTRLHVQQVFPIQACFDAQGRLYFESRLLAQYAPILKDPSPIKAETKQCTLILSSKTQSLRFYLSLTMDSQWIINSSLQNDFLHAXHKRRPTILLDSQQHRLYPTISFPWCKRVVPLKPTSTTPELLAPTKVYQVSHLIGTAEIDPMPSKTILLNNLYEQPVHLEGVIVLKRFLDGFDASSPWSDHALQLYQDFGIGTGKPQRKLLIQLRQSNSLDFVDVYLNIRKLHYPSGLIAGATVIFYNLIRKAKKTSSGSQFFCIANESTAIQVVKLHPDRDTLLLASSRSMETHLLTSFLSKEQEDVEEQEDIEEKEEKEEKEEKKKKAVVKLLCQVNSVINLVLKWECSDCGSIVRHHDCYRMCENAHRVFIANAFVHISDGTAAANASLDGERLVFELLQLTTKQRDALKQVILDYGMVSFHGGGNEDRITTVDDEGEQLDFTPFDQRQREAMYGYTIEDLVQNAKKAGQFWMYGAIQPSPRIEDESDLLTRYQLRRVTLSDNGDLLRTVERPKLRFKIFDLEPADLRLVAYDLLSQISLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NQ93</accession>
    <name>A0A1C7NQ93_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_00672</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000016">
        <property type="protein sequence ID" value="OBZ91277.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NQ93"/>
    <dbReference type="InParanoid" id="A0A1C7NQ93"/>
    <dbReference type="OrthoDB" id="10567237at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ91277.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="310" mass="35575" checksum="2369B6FB0B1F11BF" modified="2016-11-30" version="1">MESDKPFTEEEAKLFKEKITTLLKQLKQIQCILLKTSQPVQSRKRKRTALETLQQQGYNVHSEYCSYLDQLSSYARGQQALLNDIRQDLTDISKLEFNKGKDSAKINYLSRQLLQKTQEYLGQKDTVKLPSFETCEEVLNRELDRFYQTRSFPELKNQRSDLLAGTNTSLLVGNGVCALANYHPLISFGLVGGMIATYAYSYSDMSSTIAQEKPDLAHVFHALKWCMRVVNDQLQSSHDTSVEILKVVERCIVSIPLNLFFEEGSLQKATAKVDEPTKIIGYLIEIYQDIIAETKKYKDRTKFSLLLWID</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NR22</accession>
    <name>A0A1C7NR22_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_00549</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000012">
        <property type="protein sequence ID" value="OBZ91410.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NR22"/>
    <dbReference type="InParanoid" id="A0A1C7NR22"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008889834" description="Secreted protein" evidence="1">
        <location>
            <begin position="24"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ91410.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="64" mass="7483" checksum="037851F96A1B4ECB" modified="2016-11-30" version="1">MAFQLCRLVLAFWSLTVPPYISSTPLLGPCTAKVRTVWYSHWVFIRQDIPFSQVLVLAKFNRLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NRB9</accession>
    <name>A0A1C7NRB9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Putative amino acid permease YhdG</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">yhdG</name>
        <name evidence="7" type="ORF">A0J61_00470</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000010">
        <property type="protein sequence ID" value="OBZ91510.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NRB9"/>
    <dbReference type="STRING" id="101091.A0A1C7NRB9"/>
    <dbReference type="InParanoid" id="A0A1C7NRB9"/>
    <dbReference type="OrthoDB" id="5982228at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015171">
        <property type="term" value="F:amino acid transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1740.10">
        <property type="entry name" value="Amino acid/polyamine transporter I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002293">
        <property type="entry name" value="AA/rel_permease1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43243:SF4">
        <property type="entry name" value="CATIONIC AMINO ACID TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43243">
        <property type="entry name" value="INNER MEMBRANE TRANSPORTER YGJI-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13520">
        <property type="entry name" value="AA_permease_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006060">
        <property type="entry name" value="AA_transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="82"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="110"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="219"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="245"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="286"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="329"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="380"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="432"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="457"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="491"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="519"/>
            <end position="536"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OBZ91510.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="590" mass="64905" checksum="A21BB0A590340B9C" modified="2016-11-30" version="1">MSLDEKGDQFVTSSHTQEKNGTFFQSVTARYTRADPHTYLRQEGESASHFWFRRLGHIKPVELLWGDAEHSELKRALPAYHLVFIGIGAIIGTGIFVLSGLAAAKNAGPAVTISFLIAGLAAAFAALSYSELASMIPVSGSAYTYAYATMGEFIAWTIGWDLILEYMVGAATVGVGWSGYFVKFFSIVSNGRIHFADSWTQPTLAWTESPPSISYTEGHYLNVPGFIIIMLITIILILGIRHSALFNAIVVIIKLLVILIFIFALCGFMYTPNYDPYVPPNTTGNWHFFGVPGIFAAATTVFFSYIGFDMVTTAALEAKNPQRDLPIGIIGSLVISTVLYVAFCTIMTGAAKYTDFLGSSTPVLVAVQAVQDRTGKNFQWLNILVAIGAVAGLTSVLLISLMAQSRVFYSMALDGLLPPMFTILHPRFKTPWVAQLTVGFITAILSAVLPVDLLGNMTSVGTLLAFFVVHAGVIVLRFTRPEVPRRFRIPGGKYFSLIFPIIGMAISIALIAVAEVTTIWRLFIWMAIGWVIYFTYGIRHSRFNRDPVARFAEGQTKLPEGTEHDEAGIQVQEYEYIPDTHRQDPNARHA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NRJ5</accession>
    <name>A0A1C7NRJ5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">SP-RING-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">A0J61_00306</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000006">
        <property type="protein sequence ID" value="OBZ91638.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NRJ5"/>
    <dbReference type="STRING" id="101091.A0A1C7NRJ5"/>
    <dbReference type="InParanoid" id="A0A1C7NRJ5"/>
    <dbReference type="OrthoDB" id="28127at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000785">
        <property type="term" value="C:chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061665">
        <property type="term" value="F:SUMO ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016925">
        <property type="term" value="P:protein sumoylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd16650">
        <property type="entry name" value="SP-RING_PIAS-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004181">
        <property type="entry name" value="Znf_MIZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10782:SF4">
        <property type="entry name" value="TONALLI, ISOFORM E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10782">
        <property type="entry name" value="ZINC FINGER MIZ DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02891">
        <property type="entry name" value="zf-MIZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51044">
        <property type="entry name" value="ZF_SP_RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="SP-RING-type" evidence="5">
        <location>
            <begin position="350"/>
            <end position="426"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00452"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51044"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OBZ91638.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="426" mass="49070" checksum="50A8BCF5CDA0C0CC" modified="2016-11-30" version="1">MSATLYRKRRLRSTQAILTRVQIRDLGRILDISSFRQSVEFLMDPFNYFKLSKVKMAEIHNYLLEKGITNKRCPNTHIRQGDHSRMLISILFPGYPVIKASEHHYRNLRENRSPQARSIDLAYDQLPTTDKYERLDELFREDVDWHRHIDKSNIHTIDIPLKKLNKSVVVEGHASSNLNVRLFLYLWTSERMAWNPASVQLKIDDNDCLDKKQREHNEDGFYHIDVTDKSSSIQKANRRSTGSASFQFEFTGQRQPSIRHVSVCAVVEKTAEELTSQLYVQTAALYVGRAMERSSKNLPLAEKVQNKVIRLLSPYDTNDKLLLSKTEDLFLSCGEAFLTDWNDPGEEQQEDDEILAGDEVVSMLDPIILARIQHPTRCIFCTHNTCFDAKVFFDLQVNSMQWKCPICSVKIRGIQANIGSLCGLSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NRN9</accession>
    <name>A0A1C7NRN9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_00347</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000007">
        <property type="protein sequence ID" value="OBZ91609.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NRN9"/>
    <dbReference type="InParanoid" id="A0A1C7NRN9"/>
    <dbReference type="OrthoDB" id="10255641at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.129.10">
        <property type="entry name" value="Hotdog Thioesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027961">
        <property type="entry name" value="DUF4442"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029069">
        <property type="entry name" value="HotDog_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14539">
        <property type="entry name" value="DUF4442"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54637">
        <property type="entry name" value="Thioesterase/thiol ester dehydrase-isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="36"/>
            <end position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ91609.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="212" mass="23879" checksum="3E17A3D6FA6E6206" modified="2016-11-30" version="1">MSDLESSPSLLADAFSQHVQASIQLVKVALELEWTIFTRFAVGVIAATFLSVIYLVLTLRNSRRPLVVWEKLNKPLIKAFRPTIFAFLLGNINPYSKSIGFMRDRHRNRNPFRSIHATALATFAESVGELGLLSILKDSKDEITLLSLELEFKKKARGLLTASTDFNLPENEQIEVDVDGQRQVKIDVVVKDRTLDTVAIAHLVWMVQSKSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NRS5</accession>
    <name>A0A1C7NRS5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Trehalose 6-phosphate phosphatase</fullName>
            <ecNumber evidence="3">3.1.3.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">TPS2_0</name>
        <name evidence="4" type="ORF">A0J61_00836</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Removes the phosphate from trehalose 6-phosphate to produce free trehalose.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>alpha,alpha-trehalose 6-phosphate + H2O = alpha,alpha-trehalose + phosphate</text>
            <dbReference type="Rhea" id="RHEA:23420"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:16551"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58429"/>
            <dbReference type="EC" id="3.1.3.12"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Glycan biosynthesis; trehalose biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the trehalose phosphatase family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">In the C-terminal section; belongs to the trehalose phosphatase family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">In the N-terminal section; belongs to the glycosyltransferase 20 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.12" evidence="3"/>
    <dbReference type="EMBL" id="LUGH01000021">
        <property type="protein sequence ID" value="OBZ91126.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NRS5"/>
    <dbReference type="STRING" id="101091.A0A1C7NRS5"/>
    <dbReference type="InParanoid" id="A0A1C7NRS5"/>
    <dbReference type="OrthoDB" id="755951at2759"/>
    <dbReference type="UniPathway" id="UPA00299"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005946">
        <property type="term" value="C:alpha,alpha-trehalose-phosphate synthase complex (UDP-forming)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003825">
        <property type="term" value="F:alpha,alpha-trehalose-phosphate synthase (UDP-forming) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004805">
        <property type="term" value="F:trehalose-phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005992">
        <property type="term" value="P:trehalose biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd01627">
        <property type="entry name" value="HAD_TPP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1020">
        <property type="entry name" value="Trehalose-6-phosphate phosphatase related protein, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001830">
        <property type="entry name" value="Glyco_trans_20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006379">
        <property type="entry name" value="HAD-SF_hydro_IIB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003337">
        <property type="entry name" value="Trehalose_PPase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01484">
        <property type="entry name" value="HAD-SF-IIB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00685">
        <property type="entry name" value="T6PP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10788">
        <property type="entry name" value="TREHALOSE-6-PHOSPHATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10788:SF123">
        <property type="entry name" value="TREHALOSE-PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02358">
        <property type="entry name" value="Trehalose_PPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006330"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU361117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OBZ91126.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="267" mass="30157" checksum="DACDE325C705CC2E" modified="2016-11-30" version="1">MTIQYTQPLNKAALFTTYKTTHQRLFLFDYDGTLTPIVSNPADAQPTPILLHHLHELCQDPFNTVWVISGRDQEFLDTYLGKIPRLNLSAEHGSFMKKADSLDWIDMLKDADMSWKSVAISIFETYTQQNPGTVIEQKKSSITWHYRNAKDTQEATLQSQLCHQELVKIPGVDILVGKMNLEVRSLLVNKGEVVKRIKQKHASDFVMCAGDDQTDEDMFRVLKDDSAAFCVSVGPISKTTLARHSVEQSEDIVDILGQLVKTNNSTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NS77</accession>
    <name>A0A1C7NS77_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">AMP-dependent synthetase/ligase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_00105</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000002">
        <property type="protein sequence ID" value="OBZ91829.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NS77"/>
    <dbReference type="STRING" id="101091.A0A1C7NS77"/>
    <dbReference type="InParanoid" id="A0A1C7NS77"/>
    <dbReference type="OrthoDB" id="2391902at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="entry name" value="N-terminal domain of ligase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_synth/lig_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56801">
        <property type="entry name" value="Acetyl-CoA synthetase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AMP-dependent synthetase/ligase" evidence="1">
        <location>
            <begin position="31"/>
            <end position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ91829.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="92" mass="10471" checksum="AB927208C44958D2" modified="2016-11-30" version="1">MVLQSTLAPINLPESNLIEFMFSNPNHIPEDRKLLFDVFTGESLTYGQIKDRVLQFAATLEDKFNFQRGDVIALYAPNQASTLYDHHSVTIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NTF1</accession>
    <name>A0A1C7NTF1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">NADH dehydrogenase [ubiquinone] iron-sulfur protein 5</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="14">Complex I-15 kDa</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="15">NADH-ubiquinone oxidoreductase 15 kDa subunit</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">A0J61_01181</name>
        <name evidence="19" type="ORF">A0J61_01182</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="19 20" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19 20">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Mammalian complex I is composed of 45 different subunits. This is a component of the iron-sulfur (IP) fragment of the enzyme.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Mitochondrion inner membrane</location>
            <topology evidence="3">Peripheral membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Mitochondrion intermembrane space</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the complex I NDUFS5 subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="19">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000034">
        <property type="protein sequence ID" value="OBZ90773.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="LUGH01000034">
        <property type="protein sequence ID" value="OBZ90774.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NTF1"/>
    <dbReference type="STRING" id="101091.A0A1C7NTF1"/>
    <dbReference type="InParanoid" id="A0A1C7NTF1"/>
    <dbReference type="OrthoDB" id="9992197at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005758">
        <property type="term" value="C:mitochondrial intermembrane space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032981">
        <property type="term" value="P:mitochondrial respiratory chain complex I assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd24141">
        <property type="entry name" value="NDUFS5-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019342">
        <property type="entry name" value="NADH_UbQ_OxRdtase_FeS-su5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15224">
        <property type="entry name" value="NADH DEHYDROGENASE [UBIQUINONE] IRON-SULFUR PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15224:SF1">
        <property type="entry name" value="NADH DEHYDROGENASE [UBIQUINONE] IRON-SULFUR PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="17" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="13 16" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="10" id="KW-0249">Electron transport</keyword>
    <keyword evidence="12" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="9" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0679">Respiratory chain</keyword>
    <keyword evidence="7" id="KW-0813">Transport</keyword>
    <keyword evidence="19" id="KW-0830">Ubiquinone</keyword>
    <feature type="coiled-coil region" evidence="17">
        <location>
            <begin position="55"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="16">
        <location>
            <begin position="14"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="16">
        <location>
            <begin position="24"/>
            <end position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004637"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007372"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00013482"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022660"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00031222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00032739"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PIRSR" id="PIRSR619342-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="OBZ90773.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="OBZ90774.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="101" mass="11376" checksum="E82A749B6259E78E" modified="2016-11-30" version="1">MASGFGLDGGRGRCFHFWQEFNKCYASADLPQQCLDQRDDYLECLHHTKEFARITRIKTEELKQAQKKAAQAKQDALTAANSNLPKLNIIDDKASSTEVKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MTS1</accession>
    <name>A0A1C7MTS1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Neurochondrin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_11681</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01002337">
        <property type="protein sequence ID" value="OBZ80271.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MTS1"/>
    <dbReference type="STRING" id="101091.A0A1C7MTS1"/>
    <dbReference type="InParanoid" id="A0A1C7MTS1"/>
    <dbReference type="OrthoDB" id="8962942at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008709">
        <property type="entry name" value="Neurochondrin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13109">
        <property type="entry name" value="NEUROCHONDRIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13109:SF7">
        <property type="entry name" value="NEUROCHONDRIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05536">
        <property type="entry name" value="Neurochondrin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="182"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ80271.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="182" mass="20943" checksum="4F73459E36A3C1AB" modified="2016-11-30" version="1" fragment="single">DEQRDKVFTLVACLLRYFGNDWLFRSLQDTKSAKRKKEKATTEHGPAHEAFTMANFPALLVHLVSIEAKIMLDEINDRLTQEASEGKTIVSSKQARQEAMIPMYFEILEASLEYLSFHCESDKMDPEMLLKLRTTLSDFMDVVIELLKLMQDTKGDLEDDLIAQACIRLVSLWMAEEGYEMP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-06-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MU92</accession>
    <name>A0A1C7MU92_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_11594</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01002232">
        <property type="protein sequence ID" value="OBZ80358.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MU92"/>
    <dbReference type="InParanoid" id="A0A1C7MU92"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ80358.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="87" mass="9903" checksum="7DE5F16E35E12224" modified="2016-11-30" version="1">MSTHANWHTAVICINPQLSVKEARDFIDGRCSLVSIRDHRDNPICSILNLYVPPTLAERRFFFDTLMSEVPIFSASYDQTPPTGSQY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MUE6</accession>
    <name>A0A1C7MUE6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_11509</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01002129">
        <property type="protein sequence ID" value="OBZ80442.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7MUE6"/>
    <dbReference type="InParanoid" id="A0A1C7MUE6"/>
    <dbReference type="OrthoDB" id="2289822at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="344"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ80442.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="344" mass="39731" checksum="7C9E8BDB5AB7C4F1" modified="2016-11-30" version="1" fragment="single">MRVKTYDGQEFFFKAFFLAVVGDFPAMSELLAYKTHASMYGCRICLIKRTKDSGRNGFCXVGEKENEEIRQKKNFDVEEETEGIKQSTPMKYFACFSDSSFCCLDKLHLWGHHAAKQLWYLIFTKDALSLTDSKTKPCSFVDLEAKSGHARGVVWISFLLHIVPNILPDAYLEENYKSSQVNRRLTQVELDEIFRALCSLSEACSISLQYEISRLDVAKIESDIAEWHHFLKKYFKSYVFNANQHALQHIGFIIKQQGPLRYISARPLERLIGMTKLTIRSSRHPGQNAINEMNTTFVLNYHNRTIFEHSFYLFSSINNTFTLESTQPRKLLVNSVEGRKVQLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-06-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MUH5</accession>
    <name>A0A1C7MUH5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_11416</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01002008">
        <property type="protein sequence ID" value="OBZ80535.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MUH5"/>
    <dbReference type="InParanoid" id="A0A1C7MUH5"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ80535.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="140" mass="16839" checksum="9098D0D8A2ED8C32" modified="2016-11-30" version="1">MPEKETDNILKRLNYFKELHFQQLYNTMLPSFLSAHDDFLDYPGDYTDDMPQLWWKFKVQNLKVDTDLFGVPLNKFVLALRRHYSKCLMRFRSSDIKEIKLAARMLSNELVYQSRYYRSYETLLKRANTLVMFLAMESGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MUU6</accession>
    <name>A0A1C7MUU6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_11371</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001962">
        <property type="protein sequence ID" value="OBZ80580.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MUU6"/>
    <dbReference type="InParanoid" id="A0A1C7MUU6"/>
    <dbReference type="OrthoDB" id="2296888at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ80580.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="292" mass="33282" checksum="31133F014C4BFAE5" modified="2016-11-30" version="1" fragment="single">LVHAVCTHYNRQNENEFRNWLSRFKKSAKEHGTEVSKGDAHQAWKTYVSVKENKEKACSKRKYSKACVLEYFENLKGNLTGELKFDDIDMTASFNEYRKNAIEQFRIANSLYSAVQEIILLDHTNHEMKEALGQSFKEFVQKSRLEQYGVPSRLPASLRQEIEDAFEDCRFDKDYDLLEDKLQCLKKKFSIKKDKAGANVMRSLMLIPSHDAHGYNVVLSPSCSALSGCRPDFVVEVGVNDKVTNVIGEIKGSRSSADGLALDLYRIGVFGLVSLREHKLKTCLVFQTNGMF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MV83</accession>
    <name>A0A1C7MV83_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">UDENN FLCN/SMCR8-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">A0J61_11625</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the SMCR8 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01002272">
        <property type="protein sequence ID" value="OBZ80326.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MV83"/>
    <dbReference type="STRING" id="101091.A0A1C7MV83"/>
    <dbReference type="InParanoid" id="A0A1C7MV83"/>
    <dbReference type="OrthoDB" id="2289278at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032045">
        <property type="term" value="C:guanyl-nucleotide exchange factor complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005085">
        <property type="term" value="F:guanyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006914">
        <property type="term" value="P:autophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037521">
        <property type="entry name" value="FLCN/SMCR8_DENN"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31334:SF1">
        <property type="entry name" value="GUANINE NUCLEOTIDE EXCHANGE PROTEIN SMCR8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31334">
        <property type="entry name" value="SMITH-MAGENIS SYNDROME REGION GENE 8 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51834">
        <property type="entry name" value="DENN_FLCN_SMCR8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0072">Autophagy</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3" id="KW-0344">Guanine-nucleotide releasing factor</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UDENN FLCN/SMCR8-type" evidence="7">
        <location>
            <begin position="1"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="229"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="280"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="323"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="231"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="340"/>
            <end position="352"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022658"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51834"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OBZ80326.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="389" mass="44384" checksum="3A28AA21EC7001E3" modified="2016-11-30" version="1">MNDETLYYPILFSPLQLWKSGDSSKTHLLQTLGQYQSLIVDVIFSLLIGRTVLIQGSAHNKKQVQQVVRALSVFVPGQHKERHQIIDWFDSARLTQAQIGSIKLVGVNKENMDSSIHVDSSCVLDIDSKKGSLCSSPVYVEGQWINQLLDRMTLFTSDESYLAYLHTVFMSMSLKAFIYHHLYISEEFNMEEEDTQSSHSKGYVSETSSESSTLSRKWSMRLINYLKKQEDQDDDDDQSNSDDHSEENQATVTLQDIIGHRPIEHPPNITNLFSASQSRRDSMAMFGSTSSRRESTSSESSQDRMSQLSFLNFDTDDLVLQLDDNEDHSGTSSSDEDSPKKKKKHLKKHRFRRNSDVGPDGVSLTERRGRDYLQEKLKVYGDDQTIVVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MWA6</accession>
    <name>A0A1C7MWA6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Cytochrome P450 61</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">A0J61_10841</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 6">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001434">
        <property type="protein sequence ID" value="OBZ81110.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MWA6"/>
    <dbReference type="FunCoup" id="A0A1C7MWA6">
        <property type="interactions" value="424"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7MWA6"/>
    <dbReference type="InParanoid" id="A0A1C7MWA6"/>
    <dbReference type="OrthoDB" id="1372046at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016125">
        <property type="term" value="P:sterol metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd11082">
        <property type="entry name" value="CYP61_CYP710"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.630.10:FF:000021">
        <property type="entry name" value="Cytochrome P450 61"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24286:SF228">
        <property type="entry name" value="C-22 STEROL DESATURASE ERG5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24286">
        <property type="entry name" value="CYTOCHROME P450 26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0349">Heme</keyword>
    <keyword evidence="5 6 7" id="KW-0408">Iron</keyword>
    <keyword evidence="3 6 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="4 7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" description="axial binding residue" evidence="6">
        <location>
            <position position="453"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OBZ81110.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="509" mass="59167" checksum="5DEB53280A2F07CC" modified="2016-11-30" version="1">MDSTLTAIASEQLKYLSTMFNRAKASPLALSVAALAGLFLWEQIDYLRKKRHLPGPSYKVPLIGSMMDSMRPTFEKYNSKWKSGNLSCVSVFNRFIVIASNCEFSRKILNSPNFVQPAVVDSMRYILCDDNWVFKDGKDHINYRRGLNVLFQRKSLGIYLPIMDKTYQQHFDEWASHEEKERKYQWDFRELNMISSLRVFLGDFMPEEVAKQCSVEYFNITAALELVNFPIPLPGTKVYKAIRSREFIYEAFIESIKDARVRMAAGGPITCMLDNWLMAMKEQEEECRQQAKPPPHVFTDREIALTLLTFLFASQDATSSALTWTFQLLADHPDIMRKVYEEQDRLRADDPDQPITLELMEQSVYLRQVVKESLRLRPPVLMVPYQTHTDFPITDNYTVPANSMIIPTTYPALHDPVAYPEPELFNPDRWGPEGQAEKHPKNFMVFGNGPHHCIGKEYAVLHLMSTVAQATRRFEFKHYRTDDSDHIWLFATTFPKDECIMSFHPRRQF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MWP4</accession>
    <name>A0A1C7MWP4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">ATP-dependent DNA helicase</fullName>
            <ecNumber evidence="1">5.6.2.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_10728</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="5.6.2.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the helicase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.6.2.3" evidence="1"/>
    <dbReference type="EMBL" id="LUGH01001347">
        <property type="protein sequence ID" value="OBZ81223.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MWP4"/>
    <dbReference type="STRING" id="101091.A0A1C7MWP4"/>
    <dbReference type="InParanoid" id="A0A1C7MWP4"/>
    <dbReference type="OrthoDB" id="5860629at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043139">
        <property type="term" value="F:5'-3' DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000723">
        <property type="term" value="P:telomere maintenance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010285">
        <property type="entry name" value="DNA_helicase_pif1-like_DEAD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10492">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10492:SF57">
        <property type="entry name" value="ATP-DEPENDENT DNA HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05970">
        <property type="entry name" value="PIF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0227">DNA damage</keyword>
    <keyword evidence="1" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="1" id="KW-0234">DNA repair</keyword>
    <keyword evidence="1" id="KW-0347">Helicase</keyword>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA helicase Pif1-like DEAD-box helicase" evidence="2">
        <location>
            <begin position="180"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="454"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU363044"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF05970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ81223.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="454" mass="51529" checksum="85DB9DF81BCC608B" modified="2016-11-30" version="1" fragment="single">MLLYHIPGTQCFADMRTVDGTVYPTYQQAAEALGLLESDNQWEQCMAEAAVFRSAHSLRNHFCTILAFCFPTNPFALFSKFKDEMSDDYLLKLQINESIDSALVDIVKVSHDHCLFDLNETLCGQFSIDLRSYHGFQIPDEDTRSDIAYDTTIPLPVREQRRLIVIAQRRQDDANESHFNEDQLLAYQAIITAYRQPDMNTSEGRLFFVDGPGGTDKTFLFNALLHKVRKDGGRTAHSAFKIPLQVDGTSMCSIKPNSEIALLLRLTELIIWDEASMMNREEYEAVDRTFRDVLKVKDTTLSRIPFGGCLFVFGGDFRQILPVILKGSRSDIVKSCLDTSYLWQHITVLKLRLNMPVRQALNSENSNLAQQLQSFADYLLDVGNGKVETVSINTYLGPSKTDLIKLPEARVVPGNNLINLLKIELFGPKEEFKKEIEVLSEQLKYLRTQMKLGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MWU5</accession>
    <name>A0A1C7MWU5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_10713</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001335">
        <property type="protein sequence ID" value="OBZ81238.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="InParanoid" id="A0A1C7MWU5"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ81238.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="281" mass="32431" checksum="C23277C243BE2AE3" modified="2016-11-30" version="1">MYNYNNATPQSFSAPMQAMSAEDSRKLTELVHVLLAKADHIQESLNKLQISNGSQSDARSNKLSNKDVQILDCYPESLYRIVHKMDDGFMKRWYDENRGDRIYHSSFSGYFKLKALQVGELYITGKTNWNLADDDLNDQAEVMXQNTRFLARGFCVRHFKQKKNTDFFISQLNRRDSEYYARQQGYAVMRSLEDIDEDDMANAPLPLYMAMNSWLARAILSSILRKSKPKKELFQEARQKQPAKLNAPQESNASIMTEDEVVSENQFGQGVMSLTDFLNDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MWV6</accession>
    <name>A0A1C7MWV6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_11033</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001604">
        <property type="protein sequence ID" value="OBZ80919.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MWV6"/>
    <dbReference type="InParanoid" id="A0A1C7MWV6"/>
    <dbReference type="OrthoDB" id="630188at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016413">
        <property type="term" value="F:O-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029962">
        <property type="entry name" value="TBL"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32285:SF48">
        <property type="entry name" value="PROTEIN TRICHOME BIREFRINGENCE-LIKE 19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32285">
        <property type="entry name" value="PROTEIN TRICHOME BIREFRINGENCE-LIKE 9-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ80919.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="420" mass="47742" checksum="CF39513FEB46748C" modified="2016-11-30" version="1">MNLWRRLTWPRLILYFLSSVLAIHLLSTFSIPTKTIDSTRLSHDLPWYTQAHPSLSLLQQYPEYTTTHLSTQQRQTLQENMVTRAQTAAREVFKDIKGIRGSSVYADRPEASRQFRSLVDCWTTGEWIPLNQSAHWTMPHFQDPLYGSCDRKHRKTGAQGVREAVGYRWQSKCDSLEIDSANWCQVLNGRHMMLVGDLVQYQLHDVFLDSLRDGPAICFGELNCKDHTVCTAPYPDTRLRYLRNDILSTRRKMNANKGHPTAEIIEWPFASATLQKHYPILILNRSPVRESDETFIKELIHTLRALRDGPAANSLIIYRSSGIGHPFCDDATGPLKEPLGDDVLRKLPFGWSELRRRNAIARAIVEAAGGVFVDLAALTDVRPDGHVGGHDCVRYCIPGPLDGWAQVLYQVFLGLENPLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MX67</accession>
    <name>A0A1C7MX67_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_10523</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001215">
        <property type="protein sequence ID" value="OBZ81427.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MX67"/>
    <dbReference type="InParanoid" id="A0A1C7MX67"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="52"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="162"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="52"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="71"/>
            <end position="149"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ81427.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="203" mass="21652" checksum="963DD2023B5BBA1E" modified="2016-11-30" version="1">MSRTRFLNRVIEASAEKYRRISSTKERPLHTQLFARKYYNNAKGELERRAALQRSAASASRRSVTPEYRRSVASSAASGSRRSTAPSAASGSHRSAAPSAASGSRRSAASSAASGSRRSVAPSSASAASTPSSASAASAASAASAASRRQIQTEEIIRALRNIREAPTTRRPPAARNVCTALKRGRDDDEEEDAPRRKGCRLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MY94</accession>
    <name>A0A1C7MY94_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_10194</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001066">
        <property type="protein sequence ID" value="OBZ81758.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MY94"/>
    <dbReference type="STRING" id="101091.A0A1C7MY94"/>
    <dbReference type="InParanoid" id="A0A1C7MY94"/>
    <dbReference type="OrthoDB" id="2360307at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008889361" evidence="1">
        <location>
            <begin position="19"/>
            <end position="320"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ81758.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="320" mass="32819" checksum="451FB7AE40653CEB" modified="2016-11-30" version="1">MKITAAALLVLAATCVSAISSSPDVTNKSLDTNSLNDFVDVSPLLSKRTFVCPCQSNNNLIDALMGNLKADLNARVFAPVSVSFSKEATASMAFDWFLGGVLDISASTVQSIEAAASAALRASFQASLEAQINVQIYAVLESKLRTKCGGRKLTDAMLVSILTEIYAEARTLIQARLPAIGVKLHSKANTCVGSAISGIKKNVPSHIRHQIEAGNRWSIKGHGHVRGHGHGHGRFGAGVGGRGHVRGHAGGKAGAHIGAGVGAGVGAGVGAGAGAGIGGKAGIHVGAGVGGRGHGHGHGHFFSFALRIHIEYFKGLIFTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MYK8</accession>
    <name>A0A1C7MYK8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Histone H2A-alpha</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">hta1</name>
        <name evidence="7" type="ORF">A0J61_11747</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Chromosome</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the histone H2A family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01002424">
        <property type="protein sequence ID" value="OBZ80204.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MYK8"/>
    <dbReference type="STRING" id="101091.A0A1C7MYK8"/>
    <dbReference type="InParanoid" id="A0A1C7MYK8"/>
    <dbReference type="OrthoDB" id="9421954at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000786">
        <property type="term" value="C:nucleosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046982">
        <property type="term" value="F:protein heterodimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030527">
        <property type="term" value="F:structural constituent of chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.20.10">
        <property type="entry name" value="Histone, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009072">
        <property type="entry name" value="Histone-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002119">
        <property type="entry name" value="Histone_H2A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032458">
        <property type="entry name" value="Histone_H2A_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23430">
        <property type="entry name" value="HISTONE H2A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00620">
        <property type="entry name" value="HISTONEH2A"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47113">
        <property type="entry name" value="Histone-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00046">
        <property type="entry name" value="HISTONE_H2A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0158">Chromosome</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OBZ80204.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="54" mass="5544" checksum="360B1195840FE2D6" modified="2016-11-30" version="1" fragment="single">MSGGKSGGKSASGSKSQTRSAKAGLQFPVGRIHRLLRRGNYAQRVGAGAPVYLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MYN7</accession>
    <name>A0A1C7MYN7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_10039</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001009">
        <property type="protein sequence ID" value="OBZ81913.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MYN7"/>
    <dbReference type="InParanoid" id="A0A1C7MYN7"/>
    <dbReference type="OrthoDB" id="2285227at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ81913.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="473" mass="53881" checksum="0F411F350A8630C9" modified="2016-11-30" version="1">MKTIQTSLPYLQSLNIWIASSVLESSTLSFYRSFRYIASLSLREQANEKSLLDILSHHTQLKELSVLASNKMNITSRLLASVHQQCPYLEFLAMEGAHAKAPEHTTQLTYPTIHHIKVLKLQLCSGMDACHQWLAYIGTAYPQLESLALKSHKKDASQENESHPVEIYRQFWTNCPKLVDVDLCGIEIGPLFFQQLEQQQRPLKRLGLCGICSDCLVICNGLFDSSNLSTIQSMNLALPFTRTSNRFIESIGKACPRLQHLALNGYYFLTGDIAMATLLNALPCLISLEVVQANLCALDNQARHSVLLHPLKKMKFVQCMLLNEVFDYVAARCYSLQYLTLNDNRFDAPCLPHSAADEVQPTISCYKTEIHLPNQQLREFKIGRRIRTKKAPFDQIVQLFHVKQNQKKQEHWYHIDTHRENPSSVPVIARPFQEIEDKINKPHTLQQGYISLVCQSIDAVYMNKKRLVIGSIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MYY4</accession>
    <name>A0A1C7MYY4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">protein-tyrosine-phosphatase</fullName>
            <ecNumber evidence="2">3.1.3.48</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">SDP1</name>
        <name evidence="7" type="ORF">A0J61_10334</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.48" evidence="2"/>
    <dbReference type="EMBL" id="LUGH01001122">
        <property type="protein sequence ID" value="OBZ81619.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MYY4"/>
    <dbReference type="STRING" id="101091.A0A1C7MYY4"/>
    <dbReference type="InParanoid" id="A0A1C7MYY4"/>
    <dbReference type="OrthoDB" id="2017893at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033550">
        <property type="term" value="F:MAP kinase tyrosine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017017">
        <property type="term" value="F:MAP kinase tyrosine/serine/threonine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008330">
        <property type="term" value="F:protein tyrosine/threonine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043409">
        <property type="term" value="P:negative regulation of MAPK cascade"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.190.10">
        <property type="entry name" value="Protein tyrosine phosphatase superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000340">
        <property type="entry name" value="Dual-sp_phosphatase_cat-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029021">
        <property type="entry name" value="Prot-tyrosine_phosphatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016130">
        <property type="entry name" value="Tyr_Pase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000387">
        <property type="entry name" value="Tyr_Pase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020422">
        <property type="entry name" value="TYR_PHOSPHATASE_DUAL_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10159">
        <property type="entry name" value="DUAL SPECIFICITY PROTEIN PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10159:SF519">
        <property type="entry name" value="DUAL SPECIFICITY PROTEIN PHOSPHATASE MPK3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00782">
        <property type="entry name" value="DSPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00195">
        <property type="entry name" value="DSPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52799">
        <property type="entry name" value="(Phosphotyrosine protein) phosphatases II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00383">
        <property type="entry name" value="TYR_PHOSPHATASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50056">
        <property type="entry name" value="TYR_PHOSPHATASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50054">
        <property type="entry name" value="TYR_PHOSPHATASE_DUAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0904">Protein phosphatase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tyrosine-protein phosphatase" evidence="5">
        <location>
            <begin position="1"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="domain" description="Tyrosine specific protein phosphatases" evidence="6">
        <location>
            <begin position="1"/>
            <end position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008601"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013064"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OBZ81619.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="136" mass="15469" checksum="57827577F5CD80D2" modified="2016-11-30" version="1">MDIIDRARAAGQPILVHCQCGVARSATVIIAYVMKTFRLPMQEAYDHVKQLAPAINPNLSLLFQLREFEQALHAETKENTSGLLSRASSISTWKRKLSKTLFQPQPQPQPQESREWWKSKKVTFELNEPASPSVCY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MZI1</accession>
    <name>A0A1C7MZI1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Protein phosphatase</fullName>
            <ecNumber evidence="1">3.1.3.16</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_09766</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>O-phospho-L-seryl-[protein] + H2O = L-seryl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:20629"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="EC" id="3.1.3.16"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:47004"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="EC" id="3.1.3.16"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the PP2C family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.16" evidence="1"/>
    <dbReference type="EMBL" id="LUGH01000931">
        <property type="protein sequence ID" value="OBZ82182.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MZI1"/>
    <dbReference type="STRING" id="101091.A0A1C7MZI1"/>
    <dbReference type="InParanoid" id="A0A1C7MZI1"/>
    <dbReference type="OrthoDB" id="60843at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004722">
        <property type="term" value="F:protein serine/threonine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.40.10">
        <property type="entry name" value="PPM-type phosphatase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036457">
        <property type="entry name" value="PPM-type-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001932">
        <property type="entry name" value="PPM-type_phosphatase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039123">
        <property type="entry name" value="PPTC7"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12320:SF84">
        <property type="entry name" value="PROTEIN PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12320">
        <property type="entry name" value="PROTEIN PHOSPHATASE 2C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07228">
        <property type="entry name" value="SpoIIE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00331">
        <property type="entry name" value="PP2C_SIG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00332">
        <property type="entry name" value="PP2Cc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81606">
        <property type="entry name" value="PP2C-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51746">
        <property type="entry name" value="PPM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0460">Magnesium</keyword>
    <keyword evidence="1" id="KW-0464">Manganese</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1" id="KW-0904">Protein phosphatase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PPM-type phosphatase" evidence="2">
        <location>
            <begin position="80"/>
            <end position="344"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU366020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51746"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ82182.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="356" mass="39597" checksum="A9C5671350C2EF74" modified="2016-11-30" version="1">MLSTIHRKTAATATNVLKRSISKTAAPSALSSVQDNHFEYTKSLPMFDFFAQTKPKPSFKFGHGATGFAKRRANQVAIHTFNSYTSVGAQIGEDAYFRRSDAIGVADGIGGWSNTEGSDSALYSTQLMHYANLEMDRFEDIEDPLFFDYNDANPVEILQRSYDKSLVAAKKNNILGSTTACLAVLRHDELRVANIGDCGISIIRNNQYIFRSEEQQHAFNFPYQLGIQSRDQPSHAQSFTIKVQKNDIVIMGTDGLYDNLFDRDILDLVRAHVDAHTIPGAPGRPPRISNLQPQTLSDILGNTAKEISESKHRVDTPFQRRAMEEGFLMEGGKPDDISVIVAVVKDCEDSPDRRSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MZV1</accession>
    <name>A0A1C7MZV1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Zinc transporter 5</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">ZIP5_0</name>
        <name evidence="8" type="ORF">A0J61_09657</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000903">
        <property type="protein sequence ID" value="OBZ82291.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MZV1"/>
    <dbReference type="FunCoup" id="A0A1C7MZV1">
        <property type="interactions" value="304"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7MZV1"/>
    <dbReference type="InParanoid" id="A0A1C7MZV1"/>
    <dbReference type="OrthoDB" id="448280at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005385">
        <property type="term" value="F:zinc ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003689">
        <property type="entry name" value="ZIP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11040:SF44">
        <property type="entry name" value="PROTEIN ZNTC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11040">
        <property type="entry name" value="ZINC/IRON TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02535">
        <property type="entry name" value="Zip"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008889378" evidence="7">
        <location>
            <begin position="28"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="109"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="142"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="184"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="255"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="282"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="314"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="344"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="386"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="32"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="32"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="59"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="75"/>
            <end position="89"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OBZ82291.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="406" mass="44320" checksum="7F304655A56ECCC9" modified="2016-11-30" version="1">MVFKSTLLRGCVLLVFLAMFFVTTISAQEHTHEDGHTHNGVEEHNHDHGHDHDHGVSAGGSNVTAGNQESATALGEHDHEHDHGHEHAHAHGISCDMEAETAYNTPMRIGSIFIILVTSAVGIFAPIVLFRIRKPSENGIRNWILTAGKFFGTGVIISTAFIHMLPEALERFDSECIGEGWHSYHGFGGLFCMLAAFFLQLVELAALTNLDKMAAKREMEAPIEKGSVETHDEMGHVHSAGFLEHEQSMRNIGTFILELGIVMHSIIIGITLGTISEGSFQTLLIALVFHQFFEGIALGTRVNELNCKTWFKPIVMGLLFVCMTPIGVAIGIGIRSSINPPAAILAQAILDSLSAGILLYNAFVSLMSAEINQNTSFRRAPLGRKVYCFTFMYLGAALMSVLGTWA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MZZ4</accession>
    <name>A0A1C7MZZ4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Mitochondrial protein import protein MAS5</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">YDJ1</name>
        <name evidence="9" type="ORF">A0J61_09609</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000890">
        <property type="protein sequence ID" value="OBZ82341.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MZZ4"/>
    <dbReference type="FunCoup" id="A0A1C7MZZ4">
        <property type="interactions" value="749"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7MZZ4"/>
    <dbReference type="InParanoid" id="A0A1C7MZZ4"/>
    <dbReference type="OrthoDB" id="550424at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030544">
        <property type="term" value="F:Hsp70 protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009408">
        <property type="term" value="P:response to heat"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd10747">
        <property type="entry name" value="DnaJ_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd10719">
        <property type="entry name" value="DnaJ_zf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.110:FF:000048">
        <property type="entry name" value="DnaJ family protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.10.230.10:FF:000001">
        <property type="entry name" value="DnaJ subfamily A member 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.260.20:FF:000003">
        <property type="entry name" value="DnaJ subfamily A member 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.230.10">
        <property type="entry name" value="Heat shock protein DnaJ, cysteine-rich domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.260.20">
        <property type="entry name" value="Urease metallochaperone UreE, N-terminal domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01152">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012724">
        <property type="entry name" value="DnaJ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002939">
        <property type="entry name" value="DnaJ_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018253">
        <property type="entry name" value="DnaJ_domain_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044713">
        <property type="entry name" value="DNJA1/2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008971">
        <property type="entry name" value="HSP40/DnaJ_pept-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001305">
        <property type="entry name" value="HSP_DnaJ_Cys-rich_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036410">
        <property type="entry name" value="HSP_DnaJ_Cys-rich_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43888">
        <property type="entry name" value="DNAJ-LIKE-2, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01556">
        <property type="entry name" value="DnaJ_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00684">
        <property type="entry name" value="DnaJ_CXXCXGXG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00625">
        <property type="entry name" value="JDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57938">
        <property type="entry name" value="DnaJ/Hsp40 cysteine-rich domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49493">
        <property type="entry name" value="HSP40/DnaJ peptide-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00636">
        <property type="entry name" value="DNAJ_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51188">
        <property type="entry name" value="ZF_CR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 5" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="J" evidence="7">
        <location>
            <begin position="6"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="domain" description="CR-type" evidence="8">
        <location>
            <begin position="129"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="CR-type" evidence="5">
        <location>
            <begin position="129"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="381"/>
            <end position="405"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00546"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51188"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OBZ82341.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="405" mass="44519" checksum="257ACD495DBCAF50" modified="2016-11-30" version="1">MVADTKFYDVLGVSPDASESELKKAYRKLALKYHPDKNPDAGDKFKEISHAYEILSDAEKREVYDQYGEEGLNGQAGPGGMNAEDLFSQLFGGGGGFFGGGGRRGPSGPRRGKDMMHQLKVTLEDVYLGKTSKLALQKNVLCSKCDGKGGKEGAVQSCRPCNGQGIRVVMRQMGPIVQQFQQPCDVCRGTGEIINEKDRCKECLGKKITSERKILEVHIERGMRDGQKITFSKEGDQAPGIIPGDIVILLDEKPHPRFTRQGDDLIYEAKIDLLTALAGGQFAIPHLDDRVLLVNVIPGEAIQPDMVKVIPHEGMPMQRLDSRGHLFVKFTVEFPESNWTDEDTIKKLESVLPSRKALPSFGDKHLDEVVLVDAEGYQGRAGASAYDEDEDDHHHGGPGVQCSQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N0R1</accession>
    <name>A0A1C7N0R1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Serine/threonine-protein phosphatase</fullName>
            <ecNumber evidence="6">3.1.3.16</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">ppp4c</name>
        <name evidence="8" type="ORF">A0J61_09331</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:47004"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="EC" id="3.1.3.16"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the PPP phosphatase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.16" evidence="6"/>
    <dbReference type="EMBL" id="LUGH01000826">
        <property type="protein sequence ID" value="OBZ82621.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N0R1"/>
    <dbReference type="FunCoup" id="A0A1C7N0R1">
        <property type="interactions" value="645"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N0R1"/>
    <dbReference type="InParanoid" id="A0A1C7N0R1"/>
    <dbReference type="OrthoDB" id="1930084at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034399">
        <property type="term" value="C:nuclear periphery"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030289">
        <property type="term" value="C:protein phosphatase 4 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004722">
        <property type="term" value="F:protein serine/threonine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000724">
        <property type="term" value="P:double-strand break repair via homologous recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051598">
        <property type="term" value="P:meiotic recombination checkpoint signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:2000002">
        <property type="term" value="P:negative regulation of DNA damage checkpoint"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902660">
        <property type="term" value="P:negative regulation of glucose mediated signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:2001034">
        <property type="term" value="P:positive regulation of double-strand break repair via nonhomologous end joining"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:1903432">
        <property type="term" value="P:regulation of TORC1 signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd07415">
        <property type="entry name" value="MPP_PP2A_PP4_PP6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.21.10:FF:000005">
        <property type="entry name" value="Serine/threonine-protein phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047129">
        <property type="entry name" value="PPA2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006186">
        <property type="entry name" value="Ser/Thr-sp_prot-phosphatase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45619">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN PHOSPHATASE PP2A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00114">
        <property type="entry name" value="STPHPHTASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00156">
        <property type="entry name" value="PP2Ac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="Metallo-dependent phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00125">
        <property type="entry name" value="SER_THR_PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0464">Manganese</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0904">Protein phosphatase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Serine/threonine specific protein phosphatases" evidence="7">
        <location>
            <begin position="108"/>
            <end position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00048336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU004273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS00125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OBZ82621.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="302" mass="34636" checksum="8373775AC59CF3AF" modified="2016-11-30" version="1">MADLDRQLEQLRRGEIITEQEVKELCSKAKEILIEESNVQRVDAPVTICGDIHGQFHDLKELFRVGGECPETNYLFMGDFVDRGYYSVETFLLLLALKVRYPDRITLIRGNHESRQITQVYGFYDECTRKYGSANVWRYCCEVFDYLSLSAIIDDKVFCVHGGLSPTINTLDQIRTIDRKQEVPHDGAMCDLLWSDPEEIDGWGYSPRGAGYLFGADVFLHANGLDLIARAHQLVMEGYKPMFDDTIVTVWSAPNYCYRCGNIAAILELDDYLTKKYKLFEAAPQQDFRGVAQKKSLPDYFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N1U3</accession>
    <name>A0A1C7N1U3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_08844</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000721">
        <property type="protein sequence ID" value="OBZ83105.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N1U3"/>
    <dbReference type="STRING" id="101091.A0A1C7N1U3"/>
    <dbReference type="InParanoid" id="A0A1C7N1U3"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="72"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="72"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="104"/>
            <end position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ83105.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="154" mass="18188" checksum="D756B30335E94DF8" modified="2016-11-30" version="1">MDRATEAAASDLAEVRKLIEGMSALVNSQQEQQQQRQLEFAKQRQLLEQQQQKQLQQQQLLQQTQLLRKQQEQAQLEAQRQQAQREAQARLLKQQAQEQAQEQAQKEAQARLQKQQEEQARLQKQQEEQARRSRLAYNSKEKNKLAYNKKNKLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N1X4</accession>
    <name>A0A1C7N1X4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="8">E3 ubiquitin-protein ligase CCNB1IP1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">Ccnb1ip1</name>
        <name evidence="8" type="ORF">A0J61_08946</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000741">
        <property type="protein sequence ID" value="OBZ83001.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N1X4"/>
    <dbReference type="STRING" id="101091.A0A1C7N1X4"/>
    <dbReference type="InParanoid" id="A0A1C7N1X4"/>
    <dbReference type="OrthoDB" id="441210at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000795">
        <property type="term" value="C:synaptonemal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007131">
        <property type="term" value="P:reciprocal meiotic recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042448">
        <property type="entry name" value="CCNB1IP1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017907">
        <property type="entry name" value="Znf_RING_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14305">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE CCNB1IP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14305:SF0">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE CCNB1IP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14634">
        <property type="entry name" value="zf-RING_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00518">
        <property type="entry name" value="ZF_RING_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="7">
        <location>
            <begin position="13"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="259"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="115"/>
            <end position="188"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OBZ83001.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="297" mass="34396" checksum="D9A7EE5E84EDAE97" modified="2016-11-30" version="1">MAEVDIHCNVMKCRKPFSFEKQASFLKACITSCSHIFCVECANATFSKSLVCPACHASLTQNDDIILIELNPSEEYKSSVLAGLKPEVILDISTRAIAFYEYQTSQEILYRSMLQKNLEDRYNALKEKFHMAMRDLNHVIKNEKDKHTVLKKELEQEKSRCQNAVVKLEEKARQFQKLQTMYEKLKRQVTTSSMQENFQTPTAQNAPYHARNLIKMNSAQLHPHQAQQHTIILDESDVISKTERAPTVMGVQAMYHQQPLRENRPSRIPSPTRNMYSIRKHRSPSSRKSTHDPHMEM</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N2C2</accession>
    <name>A0A1C7N2C2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_08741</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000702">
        <property type="protein sequence ID" value="OBZ83207.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N2C2"/>
    <dbReference type="STRING" id="101091.A0A1C7N2C2"/>
    <dbReference type="InParanoid" id="A0A1C7N2C2"/>
    <dbReference type="OrthoDB" id="3044029at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008889438" description="Secreted protein" evidence="2">
        <location>
            <begin position="24"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="169"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="186"/>
            <end position="232"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ83207.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="338" mass="35347" checksum="580B30F950890111" modified="2016-11-30" version="1">MVAISTASLLASSITAFASFVNAYGQVAQVIDSKNFCVFLPPNDSTDRNIADTEWNAQAFCLGKAPKATNAGKLPSGFIESAHFLQTEKYIQITGQINPIRAKLNATDDGGQMDIKAPKGSSCVGWKYYVNLIEPATKTFCMRCCNDDRTCNRGISEKGCAHIIPGDYSGPNGSGSPNTNHDKPISSSTKATKSTTTAKAPKSTAKAPKATKAPETTKAPETTEAPKTTEAPKTVEDLAIPSPAVNGNSTTSASSSISTIAPASVTPSPAVSTPAGLAKDIILEASSTPVSLPTGTKNSEMLSQNNDITEQSVSGGYQFQPTIMNFVALFISVVLIIQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N2X4</accession>
    <name>A0A1C7N2X4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="16">Dynactin, isoform</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="16" type="primary">ro-3_0</name>
        <name evidence="16" type="ORF">A0J61_08563</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
            <location evidence="3">Cell cortex</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
            <location evidence="1">Microtubule organizing center</location>
            <location evidence="1">Centrosome</location>
            <location evidence="1">Centriole</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
            <location evidence="2">Cytoskeleton</location>
            <location evidence="2">Spindle</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the dynactin 150 kDa subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000671">
        <property type="protein sequence ID" value="OBZ83391.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N2X4"/>
    <dbReference type="InParanoid" id="A0A1C7N2X4"/>
    <dbReference type="OrthoDB" id="2130750at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051286">
        <property type="term" value="C:cell tip"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005814">
        <property type="term" value="C:centriole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030286">
        <property type="term" value="C:dynein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005819">
        <property type="term" value="C:spindle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005816">
        <property type="term" value="C:spindle pole body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000132">
        <property type="term" value="P:establishment of mitotic spindle orientation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000743">
        <property type="term" value="P:nuclear migration involved in conjugation with cellular fusion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.190">
        <property type="entry name" value="CAP Gly-rich-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036859">
        <property type="entry name" value="CAP-Gly_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000938">
        <property type="entry name" value="CAP-Gly_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022157">
        <property type="entry name" value="Dynactin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18916">
        <property type="entry name" value="DYNACTIN 1-RELATED MICROTUBULE-BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18916:SF6">
        <property type="entry name" value="DYNACTIN SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01302">
        <property type="entry name" value="CAP_GLY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12455">
        <property type="entry name" value="Dynactin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01052">
        <property type="entry name" value="CAP_GLY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74924">
        <property type="entry name" value="Cap-Gly domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50245">
        <property type="entry name" value="CAP_GLY_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="6" id="KW-0132">Cell division</keyword>
    <keyword evidence="10 13" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="11" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="9" id="KW-0243">Dynein</keyword>
    <keyword evidence="7" id="KW-0493">Microtubule</keyword>
    <keyword evidence="8" id="KW-0498">Mitosis</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CAP-Gly" evidence="15">
        <location>
            <begin position="33"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="84"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="13">
        <location>
            <begin position="371"/>
            <end position="706"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="13">
        <location>
            <begin position="960"/>
            <end position="987"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="13">
        <location>
            <begin position="1099"/>
            <end position="1206"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="14">
        <location>
            <begin position="119"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="14">
        <location>
            <begin position="150"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="14">
        <location>
            <begin position="171"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="14">
        <location>
            <begin position="215"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="14">
        <location>
            <begin position="243"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="14">
        <location>
            <begin position="266"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="14">
        <location>
            <begin position="285"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="14">
        <location>
            <begin position="326"/>
            <end position="338"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004114"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004544"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="OBZ83391.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="1418" mass="162185" checksum="C24CDFC238558032" modified="2016-11-30" version="1">MSSVKRSSVIRDDFAIGSRVVVNDLLGTVRFFGNTSFQTGKWVGIELDEPQGKNSGIVQGKRYFECKPNHGVFVRPANVKINEDASAGSVSPSSAMRRKSVVSAPPMQRRKSIAPPSSPTVANPPQLQNRRKSTVIPSPPASINTRRKSVVSTAPLSPATNQTPIKRRPTSLLQSAPKNAPAVSSKSTVIPNARRKSIVPPKPTKTPITKRPRSDTQSLPPTPAPTIQSPSQPSVPDMAKSRTPITAPSTPENSNDVDEDIPESLMKLERDDLEIHNDDIDSYLDGSTETVSSPLSIGTETARETVSSNDQDDEQDIETAPSEFTLEPEDEEKEEQPDEGLYKPVAQPVYGSLASSRPVSKSDQTVPLKDYEELRFKLKILENKRHEDRERFREYEKVKEEAEQFLTLRNKLQDKIAELQKDVRDTKRELKEAVAEKETYEAKYAELLDSMEMLTLDKEVAEERAEDLQQEADMLKDRIEEISLDLDILKREADMINRPPELSSTDSEQRTPLEVIQLERHNERLKEALLRLRDATIENENELNSKIKLLEQDNYELEEFKIQYEKTMEKLIEAESLVDELRVQLDDTLGAEDLVDQLTERNLALTEKLDELSATVDDLEALRELADELEENHVETEKQLQAEIDHRDMLLREQLERLRANGETLLDYEATIQQFRELVALLQNDLEKFKQKEKEEESEKMTLSSQSQAMMSLNAQLQTTVMKAQAKAIDIELRKLEAMQANDRLAMIQPYLPEAFFKTENDSISCLLLFKRLEFKAALIVKHLDQNHPVSEKIMENVTENLVSICEIKQRAGWLSSLSTRFQTHIRNCDPATFATMSKVYHELIGVERRMNAIIELFRVDQINESHCLTELQRVISQVEHMAETYLKHQEKANSDQFFGLTKALDLNADRMIVIFTFVKQSLNNAIKIDGLSIAEGLGELDMNYSEPLGRLIAFAKNSKIIAKKLMRQLEDKLEEAMTLKSEHLHRFKMLYAISAKLCTFCFETCRDITAYIDTKRGSHEQIELAHIQKLIGDKSDQIFEIAESSMWESALRTLKTLINELETTFSQVERDDKLEKISSSVAPWIQRASDIKAEVVVNHELEHKLQQHSEEIIKLIKDVRLKDQALQESDVKISLLEKRMEMAKKEMEHIKTLEEDLEKSMNQEQLYAEAMENLQHEYEALEAKNIELKKEMSKREEKRQSLLRKATFDLAEVEGDSDVQEMAGGYYEMSGQLERLRASIRYLRAENAELKSIDFVRALDLQPISKSSTSKSQHQEQLTEIARETRALVKDLRSAGASPRIVQLETRESKNTSHLWQSMKKSPDYQYQTQQSVLYTLKQRSMQLRRKVDNIQKIENDSPPVYQKIPLQQSQQQVPLGKIKIPKAISTDAASLNNTLAKRCIDIRSFNEFKRLHTIFC</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N300</accession>
    <name>A0A1C7N300_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_08562</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000671">
        <property type="protein sequence ID" value="OBZ83388.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N300"/>
    <dbReference type="STRING" id="101091.A0A1C7N300"/>
    <dbReference type="InParanoid" id="A0A1C7N300"/>
    <dbReference type="OrthoDB" id="2217172at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ83388.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="152" mass="17367" checksum="BCFEF17D531C9F2A" modified="2016-11-30" version="1">MYRKLELGYYSDNLAMDYVYILQLTELYSCEPVLHQNLKTDRGANNSRTNNRRNYYRISMVRSRFVLLLSLFGEEELSVSKATKQCIIPRSSAYLLLKEFNAGGGNALPGKALKKKKKRANKGTLVKVLPEHAEFLVKHFDSNPSSTLEMAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N3T2</accession>
    <name>A0A1C7N3T2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Ubiquitin-like 1-activating enzyme E1A</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">SAE1</name>
        <name evidence="8" type="ORF">A0J61_08224</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="2">Protein modification; protein sumoylation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the ubiquitin-activating E1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000613">
        <property type="protein sequence ID" value="OBZ83730.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N3T2"/>
    <dbReference type="FunCoup" id="A0A1C7N3T2">
        <property type="interactions" value="983"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N3T2"/>
    <dbReference type="InParanoid" id="A0A1C7N3T2"/>
    <dbReference type="OrthoDB" id="1708823at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031510">
        <property type="term" value="C:SUMO activating enzyme complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019948">
        <property type="term" value="F:SUMO activating enzyme activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016925">
        <property type="term" value="P:protein sumoylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045886">
        <property type="entry name" value="ThiF/MoeB/HesA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000594">
        <property type="entry name" value="ThiF_NAD_FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035985">
        <property type="entry name" value="Ubiquitin-activating_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000011">
        <property type="entry name" value="UBQ/SUMO-activ_enz_E1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10953:SF162">
        <property type="entry name" value="SUMO-ACTIVATING ENZYME SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10953">
        <property type="entry name" value="UBIQUITIN-ACTIVATING ENZYME E1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00899">
        <property type="entry name" value="ThiF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01849">
        <property type="entry name" value="UBIQUITINACT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69572">
        <property type="entry name" value="Activating enzymes of the ubiquitin-like proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="THIF-type NAD/FAD binding fold" evidence="7">
        <location>
            <begin position="19"/>
            <end position="323"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004718"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005673"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00044354"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OBZ83730.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="332" mass="37227" checksum="7C1F28433081EEFB" modified="2016-11-30" version="1">MTDSISKGNQQLTDEAAIYDRQIRLWGLDAQQRISKANILIAGIHALSNEVCKNIALAGVASITLLDHEVVSELDLGAQFLIQQSLVGNNKAEAAAPSIRNLNPRVQVIVDQENIKEKPDSYFESFDVVCLIHSEYELIARVDEIRRRVKKPFYAADTCGWFGYVFCDLTEHAYVLEKKIEPKAGSKQSPTVEKIPQSANYVSLDQSLEKTWSGIRPKALKRRVSPMAFLIHILFKFQKEHKRSPSEDDIQLLIEQKPKLLANMGIEDHSLLDDELISQLATLYDTEISPVAAIVGGILAQDILRTLSANELPIQNWFYYNGLDGTGLVHEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N4A1</accession>
    <name>A0A1C7N4A1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_08095</name>
        <name evidence="2" type="ORF">A0J61_11000</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001578">
        <property type="protein sequence ID" value="OBZ80951.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="LUGH01000594">
        <property type="protein sequence ID" value="OBZ83848.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N4A1"/>
    <dbReference type="InParanoid" id="A0A1C7N4A1"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ80951.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ83848.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="81" mass="9209" checksum="F1F0DE38B19DBF03" modified="2016-11-30" version="1" fragment="single">MVVSQENSRAQDKPASFVSASNSITPAMADPERVSILPDIDMSTEFTKLLQTYRELNFYLYEGGRERRVQEVQNLQNGVIQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N4C8</accession>
    <name>A0A1C7N4C8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Agenet-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_08075</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000590">
        <property type="protein sequence ID" value="OBZ83877.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N4C8"/>
    <dbReference type="STRING" id="101091.A0A1C7N4C8"/>
    <dbReference type="InParanoid" id="A0A1C7N4C8"/>
    <dbReference type="OrthoDB" id="161570at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.140">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008395">
        <property type="entry name" value="Agenet-like_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05641">
        <property type="entry name" value="Agenet"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63748">
        <property type="entry name" value="Tudor/PWWP/MBT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Agenet-like" evidence="2">
        <location>
            <begin position="396"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="146"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="286"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="445"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="646"/>
            <end position="701"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="152"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="169"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="288"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="299"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="312"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="459"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="473"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="653"/>
            <end position="673"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="684"/>
            <end position="694"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF05641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ83877.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="862" mass="98502" checksum="7BB31E107D5682AF" modified="2016-11-30" version="1">MSNLLNKHENLKQEQGHNYGKKKEKFGSFMGKLLLKGGKGLIKKPALPAIREKPLRQQSLTEEPFIRLFRARKSRESLFVSDSKLHPTEYHNGIKFSLKSDHSPLPEYQNNNEIKSDSQIDTSKYRLENGRITRWDVIGSNQVDKSLPKTVTAESENSSTREVPMPEVYPEKHSNPKDIDTQSITSISSDEDTQSVESLQSDDDVLGPWIELGMIDRTSMRTESSSNIRDTNICDKCVTQDGSKLEDRTPFDVIEPCSDCAEQWNTIFQTLSSQVLTYTNREKTDVSEQLNEQQTQENNDLHTVHNEKKKATSVSKRNSQAKSNQEPVMMPPTKSAYSIKTNIKMMTTFDKQKKESKKPTDAHYTTGAFMTRRTAKVLADPKFGFYPNPYGLTHKQKVEVLNINGNWYSGTLEVMEKGKVKVKYDDWDDQEEWIVMGSKRLRQLSNEMESEPIAPTEQVKIKASEPEEESQKIKSNSQKSSQNSSSRPKHDDYVSQILDNDKTQIFNNNEIFMTRRLAREMTDEYGFKPNSFGYRRNRAVSVTFFSKKKGERKRKEECIGYLREMHNDQIRVWYPDIHLSEWIPVGSRRLRLLSKQEEEATLSENKIDFDVQEVPVADSTKNQKITTDKTHLNLGKNTHEAIDAIGHHQKSKSNKDLPSAKEKVVSKRNKEITQDTSGSKKRTQTTTEQTKSKSIAASTSGIELRKTTHETQFLTTGAFATRRAMRQLKDDNGFVPNPYGYAFNQAVEVLNTRSGKAMFWERGTLIEMKTGKVKVHYDGWANTYDEWIMVGSRRIRIALSDTASQDTPKDNDAASTLSSYHPASISVANNETAKSDFLITESNPEIRDEVKKNKKRQILAKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N4I2</accession>
    <name>A0A1C7N4I2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Putative acyltransferase CST26</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">CST26</name>
        <name evidence="6" type="ORF">A0J61_08413</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000644">
        <property type="protein sequence ID" value="OBZ83539.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N4I2"/>
    <dbReference type="STRING" id="101091.A0A1C7N4I2"/>
    <dbReference type="InParanoid" id="A0A1C7N4I2"/>
    <dbReference type="OrthoDB" id="189226at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016746">
        <property type="term" value="F:acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036149">
        <property type="term" value="P:phosphatidylinositol acyl-chain remodeling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07990">
        <property type="entry name" value="LPLAT_LCLAT1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032098">
        <property type="entry name" value="Acyltransf_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10983">
        <property type="entry name" value="1-ACYLGLYCEROL-3-PHOSPHATE ACYLTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10983:SF16">
        <property type="entry name" value="LYSOCARDIOLIPIN ACYLTRANSFERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16076">
        <property type="entry name" value="Acyltransf_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0808">Transferase</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="202"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="domain" description="Acyltransferase C-terminal" evidence="5">
        <location>
            <begin position="122"/>
            <end position="170"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008655"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF16076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OBZ83539.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="229" mass="27511" checksum="72835D75CF763F6D" modified="2016-11-30" version="1">MKFFEFIFLKRKLEQDKDNIVNNLEKTKARNRPVWLVLFPEGTVISDEARQKSKNYAAKLNMDDLKFTLLPRTTGLKLCKDTLGNSIEWLYDLTVGYPGIEPGENPEDVMTMKRIFCDSQGPRQIHIHIRRYRVDSLPTDTEEFTEWLLARWIEKDKRMIHFNKHGTFPELSDLDNERWLGHHRTIKVKLQLQHVLKECFGYWLYSLFYIPLILLIRYLFIYFHTTYFT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N4L1</accession>
    <name>A0A1C7N4L1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein PB7E8.01</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">A0J61_08382</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000639">
        <property type="protein sequence ID" value="OBZ83569.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N4L1"/>
    <dbReference type="STRING" id="101091.A0A1C7N4L1"/>
    <dbReference type="InParanoid" id="A0A1C7N4L1"/>
    <dbReference type="OrthoDB" id="73465at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008889484" evidence="3">
        <location>
            <begin position="24"/>
            <end position="509"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="482"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="453"/>
            <end position="472"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OBZ83569.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="509" mass="58012" checksum="391EFDF2FD2E700C" modified="2016-11-30" version="1">MILPSSILFCLIWVVFVSRQVLARQLMNHTKQHATNSTVHYELVCQSDPIFCDKVDKAVAAAIDELTKVVNIKTSLLILVKYHSFCRKTCANDTYGWGSPTSQFTLPFEDGADLNYVYPQALAKQLAPYNSTSVWAQYDVEIEINSDLYTNISDDPDEINVGKYWFDDHTTEIAPEQIDFRYIVLHELLHGMGFLSAWAAYFWTKASPFRKLVDGVIDPLELQLVTPGPYWFINQDTGPAYVTGFQHTMIFDKYLVNMNRELNTTQTTLLSDIAMDMQNFCVSDNNAFIVNFLHAFNAANQSTTAHKLWLSLSEPETLQFMFQPPHNHSQFSRLPYLNQTYRNMTLLTGNDLFQVFYFEQTDPTINRPGLMISHLDDQYQNTVDFLMTQHYHMGQTLESLVQKFYQEIPVLQYNQSLPNGTLLQARYQSPIGPGILRVLDSIGYSTVLTSTSYTSDGNPKAPRSRSICDDNTTNHNLKSGSVLTSMASISLPSFYLIFLIYLCLQSNTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N4T3</accession>
    <name>A0A1C7N4T3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">tRNA-intron lyase</fullName>
            <ecNumber evidence="2">4.6.1.16</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">Tsen34</name>
        <name evidence="8" type="ORF">A0J61_07802</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>pretRNA = a 3'-half-tRNA molecule with a 5'-OH end + a 5'-half-tRNA molecule with a 2',3'-cyclic phosphate end + an intron with a 2',3'-cyclic phosphate and a 5'-hydroxyl terminus.</text>
            <dbReference type="EC" id="4.6.1.16"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the tRNA-intron endonuclease family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.6.1.16" evidence="2"/>
    <dbReference type="EMBL" id="LUGH01000549">
        <property type="protein sequence ID" value="OBZ84145.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N4T3"/>
    <dbReference type="FunCoup" id="A0A1C7N4T3">
        <property type="interactions" value="57"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N4T3"/>
    <dbReference type="InParanoid" id="A0A1C7N4T3"/>
    <dbReference type="OrthoDB" id="48041at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032473">
        <property type="term" value="C:cytoplasmic side of mitochondrial outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000213">
        <property type="term" value="F:tRNA-intron lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000379">
        <property type="term" value="P:tRNA-type intron splice site recognition and cleavage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd22363">
        <property type="entry name" value="tRNA-intron_lyase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1350.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011856">
        <property type="entry name" value="tRNA_endonuc-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036167">
        <property type="entry name" value="tRNA_intron_Endo_cat-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006677">
        <property type="entry name" value="tRNA_intron_Endonuc_cat-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006676">
        <property type="entry name" value="tRNA_splic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059049">
        <property type="entry name" value="TSEN34_N"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00324">
        <property type="entry name" value="endA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13070:SF0">
        <property type="entry name" value="TRNA-SPLICING ENDONUCLEASE SUBUNIT SEN34"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13070">
        <property type="entry name" value="TRNA-SPLICING ENDONUCLEASE SUBUNIT SEN34-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01974">
        <property type="entry name" value="tRNA_int_endo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26577">
        <property type="entry name" value="TSEN34_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53032">
        <property type="entry name" value="tRNA-intron endonuclease catalytic domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0456">Lyase</keyword>
    <keyword evidence="8" id="KW-0540">Nuclease</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="TSEN34 N-terminal" evidence="7">
        <location>
            <begin position="7"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="domain" description="tRNA intron endonuclease catalytic" evidence="6">
        <location>
            <begin position="81"/>
            <end position="157"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012573"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00034031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF26577"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OBZ84145.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="169" mass="19508" checksum="35A71B9741FE5CDE" modified="2016-11-30" version="1">MSNELVQIKKFGDKFLVFNAKDVEKLRCKHRIVGSLQGTLPQFPLQNTFYGLPLLLIPEEVYLLNKKGWSNIKEDINDTLRAVVFEYFWSKGFYLTSGIKFGGDFLLYPDDPMCVHSEYIVQTMEHDEELTPLELVGMGRLATNVKKTFVLASVIDEMMTYYSIEWAGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N4Z2</accession>
    <name>A0A1C7N4Z2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Baeyer-Villiger monooxygenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">A0J61_07861</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the FAD-binding monooxygenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000557">
        <property type="protein sequence ID" value="OBZ84087.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N4Z2"/>
    <dbReference type="STRING" id="101091.A0A1C7N4Z2"/>
    <dbReference type="InParanoid" id="A0A1C7N4Z2"/>
    <dbReference type="OrthoDB" id="74360at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004499">
        <property type="term" value="F:N,N-dimethylaniline monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051209">
        <property type="entry name" value="FAD-bind_Monooxygenase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020946">
        <property type="entry name" value="Flavin_mOase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42877:SF4">
        <property type="entry name" value="FAD_NAD(P)-BINDING DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42877">
        <property type="entry name" value="L-ORNITHINE N(5)-MONOOXYGENASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00743">
        <property type="entry name" value="FMO-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00368">
        <property type="entry name" value="FADPNR"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00469">
        <property type="entry name" value="PNDRDTASEII"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="223"/>
            <end position="245"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OBZ84087.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="496" mass="56761" checksum="57427A322B78FFC5" modified="2016-11-30" version="1">MKQPTVAVIGSGFSGLCAAIQLRKKLNIRAQVYEIKSEIGGTWNNNTYPGCACDIESALYSFSFEMNPCKKWIDWSQKYCPQQEIHQYMKQVAKKYQVYEQVQFNTQVIKAAWIEDRKQWELTLLRDQSTTEIVWFDFVFFGVGAFGVPNVPEQFKLFEGKVVHSGEWDNDYDYTDKKVAVIGSGTSAIQIVTHLAPITKHLYSFQRSPAWILPANQIKYSTYVQWLFAYVPFVMMVYRFIIFLLRDQILFKGFKSANSWFAQRTQAGVESHMRNQLIQHGRKDLIDKLIPDYQLGCKRVGVSDGYLAALCRDDVTVVRSPVVKVKGRTIETEDGEAVEVDVLCLATGFKVHQVLQDLQIYGRHGIHLNEVWNQGSAKTYKTVNIHQFPNLFMLLGPGSALGHSSVISIIEGQVNYSVDMIKYMIDHGIQSLDPTEEAQEIYWLKTSHGIKGTVWDTACASWYKKDGEIRSLWPHSVMNFFSMLKDQSFGQDYQAC</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N556</accession>
    <name>A0A1C7N556_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">polynucleotide adenylyltransferase</fullName>
            <ecNumber evidence="5">2.7.7.19</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="primary">PAPOLG</name>
        <name evidence="16" type="ORF">A0J61_07779</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the poly(A) polymerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.19" evidence="5"/>
    <dbReference type="EMBL" id="LUGH01000546">
        <property type="protein sequence ID" value="OBZ84171.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N556"/>
    <dbReference type="STRING" id="101091.A0A1C7N556"/>
    <dbReference type="InParanoid" id="A0A1C7N556"/>
    <dbReference type="OrthoDB" id="10263155at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990817">
        <property type="term" value="F:poly(A) RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031123">
        <property type="term" value="P:RNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05402">
        <property type="entry name" value="NT_PAP_TUTase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1410.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.460.10">
        <property type="entry name" value="Beta Polymerase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.590">
        <property type="entry name" value="Poly(A) polymerase predicted RNA binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043519">
        <property type="entry name" value="NT_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011068">
        <property type="entry name" value="NuclTrfase_I-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007012">
        <property type="entry name" value="PolA_pol_cen_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048840">
        <property type="entry name" value="PolA_pol_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007010">
        <property type="entry name" value="PolA_pol_RNA-bd_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10682">
        <property type="entry name" value="POLY A POLYMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10682:SF10">
        <property type="entry name" value="POLYNUCLEOTIDE ADENYLYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04928">
        <property type="entry name" value="PAP_central"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20750">
        <property type="entry name" value="PAP_NTPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04926">
        <property type="entry name" value="PAP_RNA-bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81301">
        <property type="entry name" value="Nucleotidyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55003">
        <property type="entry name" value="PAP/Archaeal CCA-adding enzyme, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81631">
        <property type="entry name" value="PAP/OAS1 substrate-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="11" id="KW-0460">Magnesium</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-0539">Nucleus</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Poly(A) polymerase nucleotidyltransferase" evidence="15">
        <location>
            <begin position="14"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="domain" description="Poly(A) polymerase central" evidence="14">
        <location>
            <begin position="191"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="domain" description="Poly(A) polymerase RNA-binding" evidence="13">
        <location>
            <begin position="341"/>
            <end position="488"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012388"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF04926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF04928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF20750"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="OBZ84171.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="493" mass="57523" checksum="94F555D7AC407C82" modified="2016-11-30" version="1">MSRLDIMDRFWVHYLQETQVIETPEEKTKRWIREKVIALFRSTLQEFIRCVKKEHGYKRDIASPILSPFGSYGIGGYVKNADIDIVMIAPHSIKRADFFKFFPANLKQLATIRDVECVKRTAVPIIKCVVDNISIDISFVRLKSNQVDPKINFLDDSLLNDLDEVCLASMDGPRVNQYILNSIKEQHLPIFCLCLQSIKHWAMRRQIYNKPSGYLNGSSWTILLLKTYLVKRNQVAELTVTYLLDQFFQLWMDWPWPVPVCVTDSIPGKDGTTVEYDSLVEFEQACMPIVSPCYPVVNAAPNVTLSTRKVLQREFERAAFILERTDLEPREVLRKLFNPVDYFARFSHFLSITTSSSRQRSHEIWTRKMPYNIPQLITMIESRKEFKLIQAIYNPKQETKTYATEREKTALRHGEWIDGSVSYTEPLNPGTLYLTHYFIGMKLDTDKEIDLSEETRSFMAYLDSKRNANDDDVSFAINHMRRKQIAKMMNYPI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N585</accession>
    <name>A0A1C7N585_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 15">Pyruvate kinase</fullName>
            <ecNumber evidence="5 15">2.7.1.40</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="primary">PYK1_1</name>
        <name evidence="18" type="ORF">A0J61_07792</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18 19">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="14 15">
            <text>pyruvate + ATP = phosphoenolpyruvate + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:18157"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.40"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3 15">Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 5/5.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 15">Belongs to the pyruvate kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.40" evidence="5 15"/>
    <dbReference type="EMBL" id="LUGH01000548">
        <property type="protein sequence ID" value="OBZ84158.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N585"/>
    <dbReference type="FunCoup" id="A0A1C7N585">
        <property type="interactions" value="397"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N585"/>
    <dbReference type="InParanoid" id="A0A1C7N585"/>
    <dbReference type="OrthoDB" id="108365at2759"/>
    <dbReference type="UniPathway" id="UPA00109">
        <property type="reaction ID" value="UER00188"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030955">
        <property type="term" value="F:potassium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004743">
        <property type="term" value="F:pyruvate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006950">
        <property type="term" value="P:response to stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd00288">
        <property type="entry name" value="Pyruvate_Kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.33.10:FF:000001">
        <property type="entry name" value="Pyruvate kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.60:FF:000001">
        <property type="entry name" value="Pyruvate kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.60">
        <property type="entry name" value="Phosphoenolpyruvate-binding domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.33.10">
        <property type="entry name" value="PK beta-barrel domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1380.20">
        <property type="entry name" value="Pyruvate kinase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001697">
        <property type="entry name" value="Pyr_Knase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015813">
        <property type="entry name" value="Pyrv/PenolPyrv_kinase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040442">
        <property type="entry name" value="Pyrv_kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011037">
        <property type="entry name" value="Pyrv_Knase-like_insert_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018209">
        <property type="entry name" value="Pyrv_Knase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015793">
        <property type="entry name" value="Pyrv_Knase_brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015795">
        <property type="entry name" value="Pyrv_Knase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036918">
        <property type="entry name" value="Pyrv_Knase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015806">
        <property type="entry name" value="Pyrv_Knase_insert_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF004491">
        <property type="entry name" value="PRK05826.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF004978">
        <property type="entry name" value="PRK06354.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01064">
        <property type="entry name" value="pyruv_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11817">
        <property type="entry name" value="PYRUVATE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00224">
        <property type="entry name" value="PK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02887">
        <property type="entry name" value="PK_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01050">
        <property type="entry name" value="PYRUVTKNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51621">
        <property type="entry name" value="Phosphoenolpyruvate/pyruvate domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50800">
        <property type="entry name" value="PK beta-barrel domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52935">
        <property type="entry name" value="PK C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00110">
        <property type="entry name" value="PYRUVATE_KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="12 15" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="9 15 18" id="KW-0418">Kinase</keyword>
    <keyword evidence="11 15" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13 18" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 15" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Pyruvate kinase barrel" evidence="16">
        <location>
            <begin position="26"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="domain" description="Pyruvate kinase C-terminal" evidence="17">
        <location>
            <begin position="386"/>
            <end position="524"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004997"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00008663"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012142"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00048152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="RuleBase" id="RU000504"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF00224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF02887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="OBZ84158.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="527" mass="57933" checksum="A7E06273FBC35ADA" modified="2016-11-30" version="1">MFSNTPTSDLQWIAEMNVDVSTSAARKSTIIGTIGPKTNSVEMITQLRNAGLNVVRMNFSHGSYEYHQSVIENTRKSCQMYPGRPTAIALDTKGPEIRTGLMRDNVETEIKAGHELTLTVNEQYKESCDDQYIYIDYKNLPKVIEKGKVVFVDDGILSLEVIEVLEDGVRVKALNDGKLSSRKGVNLPGTPVDLPALSEKDKADLQFGVQNKVDIIFASFIRRGQDVKDIREALGEAGKNIKIISKIENHQGVENFDDILEQTDGIMVARGDMGIEIPLERVFIAQKMMIAKCNLVGKPVICATQMLESMTQNPRPTRAEVSDVANAILDGADCVMLSGETAKGAYPVEAVHTMHQTCLLAESVICYPHLFNQLRALTPLPTSTTETVACAAVNAAHEQGAKAIVVLTTSGKSARLISKYRPSIPIIVVTRNPQTARQAHLHRGCFPFYYPTASSKEASRLSASYSKDYLSPLDLAPWQDDVDARIKWGMEQAIKYGFIGHNEPIVAVQGWRGGLGNTNTLRILISP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N5C2</accession>
    <name>A0A1C7N5C2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Ca3427-like PBP 2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">A0J61_09414</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Periplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the bacterial solute-binding protein SsuA/TauA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000845">
        <property type="protein sequence ID" value="OBZ82534.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N5C2"/>
    <dbReference type="InParanoid" id="A0A1C7N5C2"/>
    <dbReference type="OrthoDB" id="1363at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042597">
        <property type="term" value="C:periplasmic space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="CDD" id="cd13637">
        <property type="entry name" value="PBP2_Ca3427_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.190.10">
        <property type="entry name" value="Periplasmic binding protein-like II"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054364">
        <property type="entry name" value="Ca3427-like_PBP2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30024">
        <property type="entry name" value="ALIPHATIC SULFONATES-BINDING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30024:SF47">
        <property type="entry name" value="TAURINE-BINDING PERIPLASMIC PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13379">
        <property type="entry name" value="NMT1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22384">
        <property type="entry name" value="PBP2_Ca3427_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53850">
        <property type="entry name" value="Periplasmic binding protein-like II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="domain" description="Ca3427-like PBP 2" evidence="4">
        <location>
            <begin position="89"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="unsure residue" description="I or L" evidence="5">
        <location>
            <position position="292"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010742"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF22384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OBZ82534.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="299" mass="33641" checksum="A195CC1074EF31D7" modified="2016-11-30" version="1">MPTTIRIGYVPEHFSTPLYIARDQGYFNETGVNVELVLCPGGTGEMTSKLQDKSLDLAIALTEGLVAGISKGQDWYKIVGTFVDAPLCWALSAGKHSQHDSIDTLCNTNVAISRYGSGSHIMAFVLADQRKWLEKDKKPFDFTALNNFKAMRDAVNDGTCDYFMWETFTTKPYHDSGEVKRIGQITPPWPAFLFAAHTDLLASDTEGLTRVLHAIQQATTLFMDQKQDESVKHVMRILDYPEEDVRRWFETVHYAPQHQQVSRDALKVTLSTLLKADVISEPIKQVEELVDLEVAQLID</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N5J2</accession>
    <name>A0A1C7N5J2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_07535</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000513">
        <property type="protein sequence ID" value="OBZ84415.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="InParanoid" id="A0A1C7N5J2"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="28"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="50"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ84415.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="112" mass="12920" checksum="EA09294D426E93D5" modified="2016-11-30" version="1">MDRLEETDLEIYINVALRVAKLYADERLRDAGSNSRSKASQKKCRSTLFSPIXSSSRPRSHESASSSSKKLEGYCRCHESYTHGTEKCRLYKRMRRKAKEAEFNKDAKGKEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N613</accession>
    <name>A0A1C7N613_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">diacylglycerol kinase (ATP)</fullName>
            <ecNumber evidence="2">2.7.1.107</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">dgkA_1</name>
        <name evidence="9" type="ORF">A0J61_07355</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the eukaryotic diacylglycerol kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.107" evidence="2"/>
    <dbReference type="EMBL" id="LUGH01000491">
        <property type="protein sequence ID" value="OBZ84595.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N613"/>
    <dbReference type="STRING" id="101091.A0A1C7N613"/>
    <dbReference type="InParanoid" id="A0A1C7N613"/>
    <dbReference type="OrthoDB" id="242257at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004143">
        <property type="term" value="F:ATP-dependent diacylglycerol kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007200">
        <property type="term" value="P:phospholipase C-activating G protein-coupled receptor signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10330">
        <property type="entry name" value="Probable inorganic polyphosphate/atp-NAD kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017438">
        <property type="entry name" value="ATP-NAD_kinase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037607">
        <property type="entry name" value="DGK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000756">
        <property type="entry name" value="Diacylglycerol_kin_accessory"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001206">
        <property type="entry name" value="Diacylglycerol_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016064">
        <property type="entry name" value="NAD/diacylglycerol_kinase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11255">
        <property type="entry name" value="DIACYLGLYCEROL KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11255:SF121">
        <property type="entry name" value="DIACYLGLYCEROL KINASE (ATP)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00609">
        <property type="entry name" value="DAGK_acc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00781">
        <property type="entry name" value="DAGK_cat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111331">
        <property type="entry name" value="NAD kinase/diacylglycerol kinase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50146">
        <property type="entry name" value="DAGK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 9" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="DAGKc" evidence="8">
        <location>
            <begin position="214"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="568"/>
            <end position="598"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="28"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="38"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="75"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="568"/>
            <end position="584"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="585"/>
            <end position="598"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OBZ84595.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="598" mass="68588" checksum="8E5C010265CDE5F4" modified="2016-11-30" version="1">MSTTQTPNTNPDPKKDRDTMAGLPDVNMQDHYEKSSLETDSPTGSSPSLSPINTQSKTQDNDTVLSPPIVNHPNLIRERKDLENFRNERPSQLKNSGRINTSIRFENTEDESRPSIFLFIFVNPLSGDCKGQDLITLPFQHFRLRRFPQVQVEIHNILDEKDRALGIESIQLVDTMSKLGKLPSLEDMEEKDYKNEDHHISKTARTRHIHVWSAGGDGTVMSVFEMLVHHQIDLDNLFFSCIPFGTGNDFSQVLGWGRTIPHPNILGKKLYYLEELITERLEKSEAARLDIWQVEMTAHTSGYVRLAGPDRDDGHDAVEINAHEPNNTVPPSMVRKMCNYMSIGVQGYVGSGFEKHRTGNRWLNMMVYASESAKWLFWRHFPSVTSFIEKIVCGDQTMLVCSDPDDKQAENPPDLPYMTRTPIDFVIQNIPHIWGREVDLWGDAKSGLEVVENRSGFTDPENWTPQLANDGKMEIMSIENTFSYLKKLANIRQHVSRIGQFATPFEIVFRDPKETKKKSLWPFSGDNKFKRNNVICIMCDGEFYVLKDPKSLKFKRFAQIWTLGKHAEDSKGRLVEDEKVAEQQKHKHKHKHHQSNNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N661</accession>
    <name>A0A1C7N661_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Protoheme IX farnesyltransferase, mitochondrial</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">Heme O synthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="primary">COX10</name>
        <name evidence="13" type="ORF">A0J61_07336</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the UbiA prenyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000489">
        <property type="protein sequence ID" value="OBZ84613.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N661"/>
    <dbReference type="FunCoup" id="A0A1C7N661">
        <property type="interactions" value="442"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N661"/>
    <dbReference type="InParanoid" id="A0A1C7N661"/>
    <dbReference type="OrthoDB" id="5211at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031966">
        <property type="term" value="C:mitochondrial membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008495">
        <property type="term" value="F:protoheme IX farnesyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006784">
        <property type="term" value="P:heme A biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd13957">
        <property type="entry name" value="PT_UbiA_Cox10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.357.140:FF:000004">
        <property type="entry name" value="Protoheme IX farnesyltransferase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.357.140">
        <property type="entry name" value="UbiA prenyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00154">
        <property type="entry name" value="CyoE_CtaB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006369">
        <property type="entry name" value="Protohaem_IX_farnesylTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016315">
        <property type="entry name" value="Protohaem_IX_farnesylTrfase_mt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000537">
        <property type="entry name" value="UbiA_prenyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030470">
        <property type="entry name" value="UbiA_prenylTrfase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044878">
        <property type="entry name" value="UbiA_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01473">
        <property type="entry name" value="cyoE_ctaB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43448">
        <property type="entry name" value="PROTOHEME IX FARNESYLTRANSFERASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43448:SF2">
        <property type="entry name" value="PROTOHEME IX FARNESYLTRANSFERASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01040">
        <property type="entry name" value="UbiA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001773">
        <property type="entry name" value="COX10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00943">
        <property type="entry name" value="UBIA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0350">Heme biosynthesis</keyword>
    <keyword evidence="10 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 13" id="KW-0808">Transferase</keyword>
    <keyword evidence="6" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="5 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 12" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="77"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="101"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="142"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="166"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="197"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="221"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="264"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="291"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="323"/>
            <end position="341"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00016335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00030253"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="OBZ84613.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="360" mass="39620" checksum="6577FA3E2D25D822" modified="2016-11-30" version="1">MLRSVHRSTHFDLHHRLRCSIARYPLFPRASSHSVYSTQATDVDSTSTFKGTKFKPITQATLAELPKLYKELAKAKLGALVGLTAMCGYAIAPGAMDVSTLLFTTVGTGLCITSANAINQWIEIPYDAQMLRTRNRVLGRRALSPFHAFSFGVGTGIAGVTTLATMVNPLTACLGAANILLYTGVYTPMKRASIANTWVGAVVGGIPPMMGWAAATNSLDPGAWVLGGILYAWQFPHFNALAWNLRADYSKAGYRMMSVTDPKLNARVSLRYSLAMFPLSWGLTYLDLTSWLFAVDSTVINGALLYGAVKFWRKSNDKNAKQLFFGSIIHLPVLLGLMMVHKKYSYQEEIVEIEEEEDEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N6B9</accession>
    <name>A0A1C7N6B9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Phosphotransferase</fullName>
            <ecNumber evidence="11">2.7.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">glkA_0</name>
        <name evidence="14" type="ORF">A0J61_07383</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>D-glucose + ATP = D-glucose 6-phosphate + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17825"/>
            <dbReference type="ChEBI" id="CHEBI:4167"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61548"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.1"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="10">
            <dbReference type="Rhea" id="RHEA:17826"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>a D-hexose + ATP = a D-hexose 6-phosphate + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:22740"/>
            <dbReference type="ChEBI" id="CHEBI:4194"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:229467"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.1"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="9">
            <dbReference type="Rhea" id="RHEA:22741"/>
        </physiologicalReaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose: step 1/4.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2">Carbohydrate metabolism; hexose metabolism.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 11">Belongs to the hexokinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.-" evidence="11"/>
    <dbReference type="EMBL" id="LUGH01000495">
        <property type="protein sequence ID" value="OBZ84568.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N6B9"/>
    <dbReference type="FunCoup" id="A0A1C7N6B9">
        <property type="interactions" value="273"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N6B9"/>
    <dbReference type="InParanoid" id="A0A1C7N6B9"/>
    <dbReference type="OrthoDB" id="419537at2759"/>
    <dbReference type="UniPathway" id="UPA00109">
        <property type="reaction ID" value="UER00180"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005536">
        <property type="term" value="F:D-glucose binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008865">
        <property type="term" value="F:fructokinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004340">
        <property type="term" value="F:glucokinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006006">
        <property type="term" value="P:glucose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006096">
        <property type="term" value="P:glycolytic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001678">
        <property type="term" value="P:intracellular glucose homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd24018">
        <property type="entry name" value="ASKHA_NBD_HK_fungi"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.40:FF:000034">
        <property type="entry name" value="Phosphotransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.367.20:FF:000005">
        <property type="entry name" value="Phosphotransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.1250">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.367.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001312">
        <property type="entry name" value="Hexokinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019807">
        <property type="entry name" value="Hexokinase_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022673">
        <property type="entry name" value="Hexokinase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022672">
        <property type="entry name" value="Hexokinase_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19443:SF30">
        <property type="entry name" value="GLUCOKINASE-1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19443">
        <property type="entry name" value="HEXOKINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00349">
        <property type="entry name" value="Hexokinase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03727">
        <property type="entry name" value="Hexokinase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00475">
        <property type="entry name" value="HEXOKINASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00378">
        <property type="entry name" value="HEXOKINASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51748">
        <property type="entry name" value="HEXOKINASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8 11" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="6 11 14" id="KW-0418">Kinase</keyword>
    <keyword evidence="5 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 11" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Hexokinase N-terminal" evidence="12">
        <location>
            <begin position="29"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="domain" description="Hexokinase C-terminal" evidence="13">
        <location>
            <begin position="229"/>
            <end position="466"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004888"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00044613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00048160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU362007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF00349"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF03727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="OBZ84568.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="478" mass="53203" checksum="542DDE6D92E53F61" modified="2016-11-30" version="1">MLSAFLSQTTQAEYSAPHINGTKAQQQALNELHHQFNVTTDHARHIVKQFMEEMKKGLDQEGATVPMIPSFVTGRPTGEETGKYLALDLGGTNLRVCEFDLKGNGEFAVHQQKYVIAEELKLGPMRQLCDFIADCVDNFVCEHGSAHAHEHLQLGFTFSFPVNQTDINRGTLMHWTKGFNCSGAVGKDVVVLLQDSFLRKNLQVHIAALVNDTVGTLMANAYHRPETSMGIILGTGTNAAYYEKLKNIKKWKGGEQVFDEMVINMEWGAFDRERRVLPLTVYDNKLDRESINPQEQLFEKMISGMYLGEIARNAILHLVDQRLLFNGESSRDLNRQWGFETAYMSLIVEDESAQLDQVGHVLQDTLQIPSTTLGDRQIVQAICNAVGRRAARLAACGVAGVLAHNSGLDADSVVAIDGSVYEFFPHFEKHMMDSLHELFGQQATERVKFNLARDGSGFGAAMIAMMAHKAALVKNQKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N6W7</accession>
    <name>A0A1C7N6W7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_07124</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000465">
        <property type="protein sequence ID" value="OBZ84822.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N6W7"/>
    <dbReference type="InParanoid" id="A0A1C7N6W7"/>
    <dbReference type="OrthoDB" id="2286436at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="28"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ84822.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="104" mass="11470" checksum="5BBE20C336E6AB32" modified="2016-11-30" version="1">MNKTILSNESSSSLIHRLYLNERQLRTMVVILSLAGGLALSFLLGVIILICWYSQRQKDSPQKKITIIPTLTPPLSCLPEPSAPSAKEIDLCQCVPPPAYSPIH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N7N9</accession>
    <name>A0A1C7N7N9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_06869</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000435">
        <property type="protein sequence ID" value="OBZ85081.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N7N9"/>
    <dbReference type="InParanoid" id="A0A1C7N7N9"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="33"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="33"/>
            <end position="43"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ85081.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="75" mass="8580" checksum="FEF321E8F55589FD" modified="2016-11-30" version="1">MGYIDNLWNNRSTKPVLPVCHWQALTTVCIKNPLSTSTETQANPKKYPPRSDYIPNEEYPQLRLSQVGNMAKDDT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N830</accession>
    <name>A0A1C7N830_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Paired amphipathic helix protein pst1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">pst1_0</name>
        <name evidence="2" type="ORF">A0J61_06829</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000431">
        <property type="protein sequence ID" value="OBZ85118.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N830"/>
    <dbReference type="STRING" id="101091.A0A1C7N830"/>
    <dbReference type="InParanoid" id="A0A1C7N830"/>
    <dbReference type="OrthoDB" id="10265969at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031693">
        <property type="entry name" value="Sin3_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16879">
        <property type="entry name" value="Sin3a_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Sin3 C-terminal" evidence="1">
        <location>
            <begin position="1"/>
            <end position="246"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF16879"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ85118.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="296" mass="34561" checksum="0A09D3513D536F7D" modified="2016-11-30" version="1">MLYSRLNKLRALDAEMQANPHMGKRVNKVARDLGLYNNRFEEIDTSKGCYQAVLEMIDRFFDGDIDQQVFEEHTRYVFVTDAYLIFTIDKLVHSMVKQIQAITVDPKSVELIRLFRSDKGLESMSPRTLSVYRLKAEDIVGSDENLYKINFNNEVKNMTIQLIGKDDYMLEPTAEDKYEDYVASYMDWVNTTEGIDASSMKPTFLTRNLRPQDEHLNKIFVQSKLQYKIDQDTYHMYYIVGSEDVFVRPTLHHSKPSGSQWQEWVESSTTGWSKNLDKDTKQAMEEEARKLLSNPI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-09-13" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N879</accession>
    <name>A0A1C7N879_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_07121</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000464">
        <property type="protein sequence ID" value="OBZ84829.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N879"/>
    <dbReference type="InParanoid" id="A0A1C7N879"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ84829.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="747" mass="87168" checksum="11081C052AE338B4" modified="2016-11-30" version="1">MSILFCFPNEILVEIFSYLDDPPKSKLKDYLFLCKKLYPVVAEAYYRKVIMSRNGYTLFTTGKIKPGSQAAALARQTRSLELLFGGLKPDSFDKLLTYFPNLEILGFDNINCARALSTKSAGQNQLRRIKRLEYEFINMDNPIENPNEAKKKSITNMFLQYRYRATLTHVILLYYGRIKDTDWDLFSYINSFRHLIHLELRDETKEAYNFFNILQYNPSLVSIRYFNLRKQDKVYLRQQVVSEEALAISASDSFDDNMDTIIYNEDLVEVDLALSTITKPYLGLILNHCQKLDKLMLAMFDEDLFAFIDRIDQKKFDKLLSKLTLANSSQLWAAPKRGVFNQRDKEKTLLDRLFSLAHKIRNKRPLTVTLTLIDSSDKTAGIKVTDNQSMFLSFSVMYDDIGHPPRPMTNARQEGLREMLEGIYGEIEFNDGRSSLNPHQRIEYDSGCMDDEYEHLSVPKSTPTQSGLEIVHHFSWKSARDCARVPFNLFKYALEHCPDLKSLDLRFGCHCGCIKVGHEGKDVDKTLREGHPYLLFSRGEYLHPEQLRLLSHYYPNIERIEAGNDGRLPLSLGHHVFDKATLDFTCFKNLKSIAIDIYMHKISSHSQEYQMLTEMKHIVHTIVRINYQKGPKSKKPLLFTIWQEDPYMAGRSHMFPVAHAQSGTLEELIEKHRRYLPCILVVDIYLERELESLVILHDEKVAIIQPYNERRTLEWTKNHSVRVHHDYFVNEYHMNIDHESRKKGKKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N8A1</accession>
    <name>A0A1C7N8A1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Mitochondrial protein M19</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_07101</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000462">
        <property type="protein sequence ID" value="OBZ84849.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N8A1"/>
    <dbReference type="STRING" id="101091.A0A1C7N8A1"/>
    <dbReference type="InParanoid" id="A0A1C7N8A1"/>
    <dbReference type="OrthoDB" id="2107880at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061671">
        <property type="term" value="C:Cbp3p-Cbp6 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043022">
        <property type="term" value="F:ribosome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034551">
        <property type="term" value="P:mitochondrial respiratory chain complex III assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037653">
        <property type="entry name" value="Cbp6"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28250">
        <property type="entry name" value="CYTOCHROME B PRE-MRNA-PROCESSING PROTEIN 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28250:SF1">
        <property type="entry name" value="CYTOCHROME B PRE-MRNA-PROCESSING PROTEIN 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20180">
        <property type="entry name" value="UQCC2_CBP6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ84849.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="119" mass="13822" checksum="0CD2EDA23850CABB" modified="2016-11-30" version="1">MSTPARQEIIALYRSYMRIVRDWPEDKVRPNRGMKQVLEKRVEETFRTAHPDIHLEKAKKELESLELLLENTFKEKYPISEKILTPASNPNYYSKLISSLEASKDGQKSALAKLFGVNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N8H8</accession>
    <name>A0A1C7N8H8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein C3H8.04</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">SPAC3H8.04</name>
        <name evidence="2" type="ORF">A0J61_06513</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000396">
        <property type="protein sequence ID" value="OBZ85432.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N8H8"/>
    <dbReference type="STRING" id="101091.A0A1C7N8H8"/>
    <dbReference type="InParanoid" id="A0A1C7N8H8"/>
    <dbReference type="OrthoDB" id="8625101at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033473">
        <property type="entry name" value="Atos-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025261">
        <property type="entry name" value="Atos-like_cons_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051506">
        <property type="entry name" value="ATOS_Transcription_Regulators"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13199">
        <property type="entry name" value="GH03947P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13199:SF11">
        <property type="entry name" value="PROTEIN ATOSSA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13889">
        <property type="entry name" value="Chromosome_seg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13915">
        <property type="entry name" value="DUF4210"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01177">
        <property type="entry name" value="DUF4210"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Atos-like conserved" evidence="1">
        <location>
            <begin position="288"/>
            <end position="360"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM01177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ85432.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="495" mass="57030" checksum="52298A9A56B33B20" modified="2016-11-30" version="1">MPIPVLIDRQDTYARLFKTILSSNSLCLKSHENDTCLFEPIIADGIVIHILQKESDVLLERWVFKIQPFQTTNIVSYEHVLQFIQDHRQWVADFYTIVFADHAPSDQCYSASSYKSTMEFRSDAQLKAERFQLDPDLSIQVVFDQNPSRLKKPMICLQALSSHRETTLLPWQSLDEFSPLADHTAKSHVSPSHHTPIIAVRRLSRLSLSAIDDDYETAEENDHEESYASIPIPAPHMQYTHHHGHRTTLAYSTSPTNFMHRYHHHHLNTDHERRHSLTNDLLHHQGSFVGSFEESLLSGRMSSMPSKPITFHCQLGVLGYGDCKPSLKCPPHWSIVFPATFYNLPENDQYQDQTTTTPYVGLVDLEEHANTITSKGKKEAPPGYRIPPKGQIQVVIKNPNKTAVKLFLIPYDFTDMPKNTKTFLRQKSYTTDSQKPLLRYAIHLQFVRNERKRIYLCKNMRIVFTNRKADAREKFHVVCEGPKEPVYLPSLNTAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N8J0</accession>
    <name>A0A1C7N8J0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_06556</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000401">
        <property type="protein sequence ID" value="OBZ85391.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N8J0"/>
    <dbReference type="InParanoid" id="A0A1C7N8J0"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008889542" evidence="2">
        <location>
            <begin position="19"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="105"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="105"/>
            <end position="117"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ85391.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="129" mass="13665" checksum="A533FD5E9D503220" modified="2016-11-30" version="1">MVKSVLIASLLFGLSVSALPTKRDDAVKAETLCSPTAAEEACSFLRNHPSKDYLFLLPTECESLAPPEAKLERASVVIIIGEDFKPEVQLKNVCEAANIAERLLGSTSADKTETPSAASEADVKASKAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-06-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N921</accession>
    <name>A0A1C7N921_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_06317</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000376">
        <property type="protein sequence ID" value="OBZ85633.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N921"/>
    <dbReference type="STRING" id="101091.A0A1C7N921"/>
    <dbReference type="InParanoid" id="A0A1C7N921"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ85633.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="82" mass="9897" checksum="F8A23F4F56EA26C8" modified="2016-11-30" version="1">MKQIVNYCERHPRLLRVRDSVLKNLHDPNIPHHLIHNYYVEIAFKYLNDSLSILWEHWETDYRVCMNEYGGRSPVLLADFLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N986</accession>
    <name>A0A1C7N986_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_06459</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000390">
        <property type="protein sequence ID" value="OBZ85488.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N986"/>
    <dbReference type="InParanoid" id="A0A1C7N986"/>
    <dbReference type="OrthoDB" id="10255641at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="32"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ85488.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="99" mass="11360" checksum="E60BA89A5BB96EF3" modified="2016-11-30" version="1">MSLHSPLTEALYGHLRASVYLAQVALELEWTIFSRLLAILILLTFSYILYILISLKDGRHPLRIWEKLGKPVVKIFRPWTFARLLNNSDPYASSIGKSC</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N9D8</accession>
    <name>A0A1C7N9D8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Signal recognition particle receptor subunit beta</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">Srprb</name>
        <name evidence="14" type="ORF">A0J61_06717</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SRP receptor beta subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000419">
        <property type="protein sequence ID" value="OBZ85236.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N9D8"/>
    <dbReference type="FunCoup" id="A0A1C7N9D8">
        <property type="interactions" value="549"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N9D8"/>
    <dbReference type="InParanoid" id="A0A1C7N9D8"/>
    <dbReference type="OrthoDB" id="41266at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005785">
        <property type="term" value="C:signal recognition particle receptor complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042802">
        <property type="term" value="F:identical protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005047">
        <property type="term" value="F:signal recognition particle binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043001">
        <property type="term" value="P:Golgi to plasma membrane protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034067">
        <property type="term" value="P:protein localization to Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045047">
        <property type="term" value="P:protein targeting to ER"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd04105">
        <property type="entry name" value="SR_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024156">
        <property type="entry name" value="Small_GTPase_ARF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006689">
        <property type="entry name" value="Small_GTPase_ARF/SAR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019009">
        <property type="entry name" value="SRP_receptor_beta_su"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45909">
        <property type="entry name" value="ADP-RIBOSYLATION FACTOR-RELATED PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45909:SF1">
        <property type="entry name" value="ADP-RIBOSYLATION FACTOR-RELATED PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09439">
        <property type="entry name" value="SRPRB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00328">
        <property type="entry name" value="SAR1GTPBP"/>
    </dbReference>
    <dbReference type="SMART" id="SM00177">
        <property type="entry name" value="ARF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51417">
        <property type="entry name" value="ARF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="8 11" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="12" id="KW-0460">Magnesium</keyword>
    <keyword evidence="9 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10 14" id="KW-0675">Receptor</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 13" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="6"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="40"/>
            <end position="47"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="47"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="64"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="86"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="145"/>
            <end position="148"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005619"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00020256"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR606689-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR606689-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="OBZ85236.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="226" mass="25633" checksum="E02A1E72099E3070" modified="2016-11-30" version="1">MDNDLLIKAILALVVLTALTLIALTVYTKKQNKNTILLLGISDAGKTSMYILLKSGKNHPTVSSMKENEGQLTLNNKIFDLVDIPGHDRVRFRYVEFLPVTRSIVFVVDSTTITRKIRPAAEYLYDILAQPQVQKQKIPVLIACNKSDMITALPTDKIKLLFETELNRLRGTRTARVEQQESDEQEAFLGYEGEAFKFEHIDNTVEFKSCSVQDQKVDLVKDWIVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N9J6</accession>
    <name>A0A1C7N9J6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Diphthamide biosynthesis protein 3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">dph3</name>
        <name evidence="9" type="ORF">A0J61_06615</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>2 [3Fe-4S](0)-[protein] + 2 Fe(2+)-[Dph3] + NADH = 2 [4Fe-4S](1+)-[protein] + 2 [Dph3] + NAD(+) + H(+)</text>
            <dbReference type="Rhea" id="RHEA:71239"/>
            <dbReference type="Rhea" id="RHEA-COMP:17997"/>
            <dbReference type="Rhea" id="RHEA-COMP:17998"/>
            <dbReference type="Rhea" id="RHEA-COMP:18001"/>
            <dbReference type="Rhea" id="RHEA-COMP:18002"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
            <dbReference type="ChEBI" id="CHEBI:33723"/>
            <dbReference type="ChEBI" id="CHEBI:47402"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:83228"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>[3Fe-4S](1+)-[protein] + Fe(2+)-[Dph3] = [3Fe-4S](0)-[protein] + Fe(3+)-[Dph3]</text>
            <dbReference type="Rhea" id="RHEA:71235"/>
            <dbReference type="Rhea" id="RHEA-COMP:17996"/>
            <dbReference type="Rhea" id="RHEA-COMP:17997"/>
            <dbReference type="Rhea" id="RHEA-COMP:18002"/>
            <dbReference type="Rhea" id="RHEA-COMP:18003"/>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
            <dbReference type="ChEBI" id="CHEBI:29034"/>
            <dbReference type="ChEBI" id="CHEBI:33751"/>
            <dbReference type="ChEBI" id="CHEBI:47402"/>
            <dbReference type="ChEBI" id="CHEBI:83228"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Protein modification; peptidyl-diphthamide biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the DPH3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000408">
        <property type="protein sequence ID" value="OBZ85329.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N9J6"/>
    <dbReference type="FunCoup" id="A0A1C7N9J6">
        <property type="interactions" value="163"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N9J6"/>
    <dbReference type="InParanoid" id="A0A1C7N9J6"/>
    <dbReference type="OrthoDB" id="66964at2759"/>
    <dbReference type="UniPathway" id="UPA00559"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017183">
        <property type="term" value="P:protein histidyl modification to diphthamide"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.660.10:FF:000001">
        <property type="entry name" value="Diphthamide biosynthesis 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.660.10">
        <property type="entry name" value="DPH Zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044248">
        <property type="entry name" value="DPH3/4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007872">
        <property type="entry name" value="DPH_MB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036671">
        <property type="entry name" value="DPH_MB_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21454:SF31">
        <property type="entry name" value="DIPHTHAMIDE BIOSYNTHESIS PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21454">
        <property type="entry name" value="DPH3 HOMOLOG-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05207">
        <property type="entry name" value="Zn_ribbon_CSL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144217">
        <property type="entry name" value="CSL zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51074">
        <property type="entry name" value="DPH_MB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0408">Iron</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DPH-type MB" evidence="8">
        <location>
            <begin position="4"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00024032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00036267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00041070"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00048125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51074"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OBZ85329.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="83" mass="9583" checksum="F5C420A9787483EF" modified="2016-11-30" version="1">MTSFYDEIEIEDMEFNEDDQIYTYPCPCGDKFEISIDDLRDGDDVARCPSCSLIIRVIYDPDEFADEDDEETSYEIDTSISVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-06-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N9N8</accession>
    <name>A0A1C7N9N8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_06134</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000356">
        <property type="protein sequence ID" value="OBZ85811.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N9N8"/>
    <dbReference type="InParanoid" id="A0A1C7N9N8"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ85811.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="99" mass="11598" checksum="C5A1D2443751FF96" modified="2016-11-30" version="1">MTLFTIVDHQGLLYILLIKKFPRIWYMTKNTREQYLPLVNDNISSNAAKGTIEVKSSCLYDFLTSRAQLFSDKSKRFEVDYGQLDQCLSNPQQYSETFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N9R6</accession>
    <name>A0A1C7N9R6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Regulator of V-ATPase in vacuolar membrane protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">rav1</name>
        <name evidence="6" type="ORF">A0J61_06532</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000398">
        <property type="protein sequence ID" value="OBZ85419.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="FunCoup" id="A0A1C7N9R6">
        <property type="interactions" value="124"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N9R6"/>
    <dbReference type="InParanoid" id="A0A1C7N9R6"/>
    <dbReference type="OrthoDB" id="342131at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043291">
        <property type="term" value="C:RAVE complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007035">
        <property type="term" value="P:vacuolar acidification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052208">
        <property type="entry name" value="DmX-like/RAVE_component"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022033">
        <property type="entry name" value="Rav1p_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13950:SF9">
        <property type="entry name" value="RABCONNECTIN-3A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13950">
        <property type="entry name" value="RABCONNECTIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12234">
        <property type="entry name" value="Rav1p_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="10"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="RAVE complex protein Rav1 C-terminal" evidence="5">
        <location>
            <begin position="633"/>
            <end position="1271"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="2075"/>
            <end position="2116"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="2117"/>
            <end position="2158"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="882"/>
            <end position="907"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1292"/>
            <end position="1319"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1822"/>
            <end position="1876"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="894"/>
            <end position="904"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="1295"/>
            <end position="1309"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="1831"/>
            <end position="1843"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="1858"/>
            <end position="1873"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF12234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OBZ85419.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="2217" mass="252309" checksum="D61206424433273F" modified="2016-11-30" version="1">MFLEQICPGQVNSYPQALHTFAFDQDRFVIYATGSKIVIYADPDKLIQTIVAEDLFQHHKEAEPITSVAGNCVTGQIALSYNNQVAILKPEQGRGKIEWHLESVLNVLFTVNCLDWSAHNTLLVAGTEIALWRFDKDASNWKVEYQCKPATQITFAKFEPKSHMFATIGKFDRLVTIWYPASTTDKHNSNYNCIFISHPKYVTHFVWRHLPSDNGTRENDCTLFTMARDGIGRFWSPTDLDQPHMLYMCAVIDSNQSLVTSEQDQSANDHINDGSDFSPIHYIGCDELASAVNIRFRSHSKHERFDQLVERIRDRIRDTPDLLFRIQADGSLTLWGVQHLNTTPRRIPRVYVVLRVDKAIDPLDAIYFLSPTFILHDYGHIQSSSTIKSIELSLLARNPYGQVRCYSLNLIDFLDSTSFSAKLHLKYTWLGHQHAIVKLYQTQKNRFCTIGIDGQMNVWKYELRESYGKMTTQLQLDCSLFIDSDKLLAVPIDKDKYLAVYDGHLLKLYEFGQHDCHLHQSRTLTSEGKNLEISSLHVYNIEDPETHETSFLLVGVSATSKTILNWHLVPDNSQLNVAFLGSKEMTWQSEPTMIVSASQWATNTASKLLYRLAMHKRTAFVILVDNVLFFYSISIANEEVEWETLYTLDISCLKSPIQSIKFAPGVMAIVCGEEANILSIWTEMRSGSPPECSQLMTFDQSIQDLVWNVTSDAQYILAIAFPKRIEIFGQKRASGLDAVEESWTCYTKFEVNTPKSITALAWVDCGVLIAAAGNQLLSYLKWLTEDDTVNASIQSYKTSKLEPMTSIFDISYEMNGPLPFYHPYHLVHYTMWGKMDLVHNVLLSLYNFLKQFVDDEDNTISEFPTISLPTILKLQNDHEKKTRQKGGYGGLFDDSSDEFNDEDGDSTRHLTLNEAKNLAYSLKSKSLPGINEKEKMHLIAMVNTIVEITDQGESLDENGARFIALLENHFHLKQALAENEEQIDLAPKDYVWALHSQSQDLLLERCVRLCKDRFVWKDARSLGMFMWLQKIDVVREQMSQIARNTYLSKQDDRDPIDCTLFYFALRKKNLVQGLWNTTSHHKEQGIMKKFLANDFNDPRWQRAASKNAYALLGKQRFEYAAAFFLLADKLKDAVNVILKNVKDYQLAIAICRVYEGDHSLLLKEVLENTVIPVAIETNDCWLAGIAFWLLNKQKEAVRSIVVPLSQFSEKHIDTSETDSAATVQNPNSFILYNHLKASLQQPNVVSYDVEYMFYLQVAQSYERLGCPLLALYVLTEYYMPPPPTFQSIAYEEEVKDEKESKPSLDRAEDLFSSSTPQNSSFASDIFADENDSLFKTNKPSYASNLFDESEDDIFASSNKQTSDNLFDEVEENMYSDKDSQKTEKNREYDGLDVYKAMLAIRMLQTFFHAATALYNGLGEISDVHEATYRDNFISNRNTLLDLGASLKIPADILSRLLMEKSIETDVFPLYLHILNEQVPENFDVHQFLRAFKVGCFEVNEVALMPQELDYATLAFVENWSSHVVKTFPIWSDLRSRYCNPKTASLMTHQIILTTYIGAILITLRERYYEKAWTFLCHFKFFLEALGSNDSLTAIKNCLALLLKDEVRMAEIAPDEFEDFSDESMFGYDMHEEIYRPLIDSQDRAAGSNMLEIASLNFVLSSLEHSMQCQGRHNSLSEQLSDYTWTTLLDPIAYRIHYLKQTVLQQLENNTARHNVTKQFKTLRQKKFWRSIKSLSTFDRLLPFVDPSLPSINVLSVDDRIDYCRSVYHSTSTVYGFCLNPSMRDTMAICMKSEIQEIDLTKATDNTGAPLIRARSVSSFGLGPDHHVDSYPDTEEDDSDFEDSESLHAAKQTRRNRFPSSSKISSNNSPIVSPAGSRTFDEHVQRGLQNLNLDYLQDSLKKSFPKGVEAGRTPAATSPAVLDQAERESMISLRRPVTASCMETHPHYPFYITGCEGTNGGPSAILWQFGQEKEIASYYGCKNKTTRIHFDRFGQKFGAADASGSLCLWRFDAHAHSNKAYYTLQCHSKATRDFVFVNSSSLIATAGTSVTMSRKRDHVVLWDTLLPASKAMVCALPGHDGGAYAIAYEPDNQLLFSGGKKGEIVVSDLRQRTTMHTFTAHDSRIRSIAIDSENKSLITGSIDGELKIWDASTYKLHQTFEIQPRNRFLAPSFNRIPLKAFGVTQIQILSNDSNIYTSGPNGIIKCNRVPVIHSSLTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N9W1</accession>
    <name>A0A1C7N9W1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Prefoldin subunit 5</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">PFDN5</name>
        <name evidence="3" type="ORF">A0J61_06559</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the prefoldin subunit alpha family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000401">
        <property type="protein sequence ID" value="OBZ85396.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N9W1"/>
    <dbReference type="FunCoup" id="A0A1C7N9W1">
        <property type="interactions" value="728"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N9W1"/>
    <dbReference type="InParanoid" id="A0A1C7N9W1"/>
    <dbReference type="OrthoDB" id="10267474at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032153">
        <property type="term" value="C:cell division site"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051286">
        <property type="term" value="C:cell tip"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016272">
        <property type="term" value="C:prefoldin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015631">
        <property type="term" value="F:tubulin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032968">
        <property type="term" value="P:positive regulation of transcription elongation by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990113">
        <property type="term" value="P:RNA polymerase I assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990114">
        <property type="term" value="P:RNA polymerase II core complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990115">
        <property type="term" value="P:RNA polymerase III assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007021">
        <property type="term" value="P:tubulin complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd23157">
        <property type="entry name" value="Prefoldin_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.370">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011599">
        <property type="entry name" value="PFD_alpha_archaea"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009053">
        <property type="entry name" value="Prefoldin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004127">
        <property type="entry name" value="Prefoldin_subunit_alpha"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00293">
        <property type="entry name" value="prefoldin subunit alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12674">
        <property type="entry name" value="PREFOLDIN SUBUNIT 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12674:SF2">
        <property type="entry name" value="PREFOLDIN SUBUNIT 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02996">
        <property type="entry name" value="Prefoldin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46579">
        <property type="entry name" value="Prefoldin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="6"/>
            <end position="40"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ85396.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="153" mass="17286" checksum="B8C3F7544492B528" modified="2016-11-30" version="1">MSQQQVNIADLDLASLQQVKSQLEEELSHLTQSYTKLKGVQARFTDCADSVNALKTERADELLFLNLDVYLYVPGKISDVNKVIVDVGTGYYIEKLTRVFLSQSVGDASKFYNDKVDYVKKNLGTLEKTITDKQSTLRAIVSVMQDKIQQEQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NAC0</accession>
    <name>A0A1C7NAC0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Ubiquinone biosynthesis monooxygenase COQ6, mitochondrial</fullName>
            <ecNumber evidence="11">1.14.15.45</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">2-methoxy-6-polyprenolphenol 4-hydroxylase</fullName>
            <ecNumber evidence="11">1.14.15.46</ecNumber>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11 14" type="primary">COQ6</name>
        <name evidence="14" type="ORF">A0J61_05885</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">FAD-dependent monooxygenase required for two non-consecutive steps during ubiquinone biosynthesis. Required for the C5-ring hydroxylation during ubiquinone biosynthesis by catalyzing the hydroxylation of 4-hydroxy-3-(all-trans-polyprenyl)benzoic acid to 3,4-dihydroxy-5-(all-trans-polyprenyl)benzoic acid. Also acts downstream of coq4, for the C1-hydroxylation during ubiquinone biosynthesis by catalyzing the hydroxylation of 2-methoxy-6-(all-trans-polyprenyl)phenol to 2-methoxy-6-(all-trans-polyprenyl)benzene-1,4-diol. The electrons required for the hydroxylation reaction are funneled indirectly to coq6 from NADPH via a ferredoxin/ferredoxin reductase system.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>a 2-methoxy-6-(all-trans-polyprenyl)phenol + 2 reduced [2Fe-2S]-[ferredoxin] + O2 + 2 H(+) = a 2-methoxy-6-(all-trans-polyprenyl)benzene-1,4-diol + 2 oxidized [2Fe-2S]-[ferredoxin] + H2O</text>
            <dbReference type="Rhea" id="RHEA:81183"/>
            <dbReference type="Rhea" id="RHEA-COMP:9551"/>
            <dbReference type="Rhea" id="RHEA-COMP:10000"/>
            <dbReference type="Rhea" id="RHEA-COMP:10001"/>
            <dbReference type="Rhea" id="RHEA-COMP:10858"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:33737"/>
            <dbReference type="ChEBI" id="CHEBI:33738"/>
            <dbReference type="ChEBI" id="CHEBI:62731"/>
            <dbReference type="ChEBI" id="CHEBI:84166"/>
            <dbReference type="EC" id="1.14.15.46"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>a 4-hydroxy-3-(all-trans-polyprenyl)benzoate + 2 reduced [2Fe-2S]-[ferredoxin] + O2 + 2 H(+) = a 3,4-dihydroxy-5-(all-trans-polyprenyl)benzoate + 2 oxidized [2Fe-2S]-[ferredoxin] + H2O</text>
            <dbReference type="Rhea" id="RHEA:81195"/>
            <dbReference type="Rhea" id="RHEA-COMP:9514"/>
            <dbReference type="Rhea" id="RHEA-COMP:10000"/>
            <dbReference type="Rhea" id="RHEA-COMP:10001"/>
            <dbReference type="Rhea" id="RHEA-COMP:10930"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:33737"/>
            <dbReference type="ChEBI" id="CHEBI:33738"/>
            <dbReference type="ChEBI" id="CHEBI:64694"/>
            <dbReference type="ChEBI" id="CHEBI:78396"/>
            <dbReference type="EC" id="1.14.15.45"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 11">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="11">Cofactor biosynthesis; ubiquinone biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="11">Component of a multi-subunit COQ enzyme complex, composed of at least COQ3, COQ4, COQ5, COQ6, COQ7 and COQ9.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="11">Mitochondrion inner membrane</location>
            <topology evidence="11">Peripheral membrane protein</topology>
            <orientation evidence="11">Matrix side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the UbiH/COQ6 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.14.15.45" evidence="11"/>
    <dbReference type="EC" id="1.14.15.46" evidence="11"/>
    <dbReference type="EMBL" id="LUGH01000332">
        <property type="protein sequence ID" value="OBZ86065.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NAC0"/>
    <dbReference type="FunCoup" id="A0A1C7NAC0">
        <property type="interactions" value="339"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NAC0"/>
    <dbReference type="InParanoid" id="A0A1C7NAC0"/>
    <dbReference type="OrthoDB" id="683240at2759"/>
    <dbReference type="UniPathway" id="UPA00232"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031314">
        <property type="term" value="C:extrinsic component of mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0120538">
        <property type="term" value="F:2-methoxy-6-polyprenolphenol 4-hydroxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106364">
        <property type="term" value="F:4-hydroxy-3-all-trans-polyprenylbenzoate oxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016712">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="3.50.50.60:FF:000021">
        <property type="entry name" value="Ubiquinone biosynthesis monooxygenase COQ6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03193">
        <property type="entry name" value="COQ6_monooxygenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018168">
        <property type="entry name" value="Ubi_Hdrlase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010971">
        <property type="entry name" value="UbiH/COQ6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051205">
        <property type="entry name" value="UbiH/COQ6_monooxygenase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000689">
        <property type="entry name" value="UbQ_mOase_COQ6"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01988">
        <property type="entry name" value="Ubi-OHases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43876">
        <property type="entry name" value="UBIQUINONE BIOSYNTHESIS MONOOXYGENASE COQ6, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43876:SF7">
        <property type="entry name" value="UBIQUINONE BIOSYNTHESIS MONOOXYGENASE COQ6, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00420">
        <property type="entry name" value="RNGMNOXGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01304">
        <property type="entry name" value="UBIH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 11" id="KW-0274">FAD</keyword>
    <keyword evidence="3 11" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="10 11 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="9 11" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5 11" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="8 11 14" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="7 11" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="14" id="KW-0830">Ubiquinone</keyword>
    <keyword evidence="4 11" id="KW-0831">Ubiquinone biosynthesis</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="27"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding" evidence="13">
        <location>
            <begin position="28"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding" evidence="13">
        <location>
            <begin position="360"/>
            <end position="443"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005349"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022688"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="OBZ86065.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="500" mass="56443" checksum="37998391849B78E4" modified="2016-11-30" version="1">MWRSTTRTITHHVQRRSMATSVDLNKVYDVVIIGGGVAGVTLACSLASSPAMRHHRIALVEAMDLTGVRQWQPKQNEYSNRVVSLTPSSLNFFKRIGVADHMVMDRVNGYRDMQVWDGVTDARIHLDSALLQQKESNTIAYMVENLNVQSAALKRMEQCQSEDVHVDLIQKVKVAQIENEQQSTSTDQLDLQDWPTVCLDNGDRLKARLLVGADGVNSPVRSFAGIESLGWDYDAHGVVATLKLDAERHNNSAWQRFLPTGPIAMLPLNDQYASMVWSTTPAIAKMLKNVSSDDFCHLVNAAFRMSHIDLKYLYKQINTSTYQSNCDIQEEYLWRESVATKSLNEHQLVQRELSLPPQVTQVQDRSRASFPLRLRNSEQYVTDRVALVGDAAHAIHPLAGQGLNQGLLDVECLSHLLEKGTREGQDIGSIHLLRQYAHERYLRNIAMLSTCDKLHRLFSTDAAPITWMRSIGLNTVNNLDFVKTEMMKYAMGIEYNGDYK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NAX9</accession>
    <name>A0A1C7NAX9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Tetraspanin Tsp2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">A0J61_06160</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000359">
        <property type="protein sequence ID" value="OBZ85786.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NAX9"/>
    <dbReference type="STRING" id="101091.A0A1C7NAX9"/>
    <dbReference type="InParanoid" id="A0A1C7NAX9"/>
    <dbReference type="OrthoDB" id="2156690at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018499">
        <property type="entry name" value="Tetraspanin/Peripherin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008952">
        <property type="entry name" value="Tetraspanin_EC2_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19282">
        <property type="entry name" value="TETRASPANIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19282:SF556">
        <property type="entry name" value="TETRASPANIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00335">
        <property type="entry name" value="Tetraspanin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48652">
        <property type="entry name" value="Tetraspanin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="100"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="140"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="173"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="265"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OBZ85786.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="332" mass="37872" checksum="959760E647DECFDF" modified="2016-11-30" version="1">MNPPTKKGGHPYATQSSESSSYVSLQNLGNHPNRPSILLNHDLDEQADLPEPVLPWMKSESRQSLGSQRSSIDTSSLHIMKRQIPDPSTKKKQRWTKHKWWLLLSNTLLFCYGLGILLLALLTYFKFYLRADVVIVGERMILNLILATGVICLFTSVVGYVGIMLNNRAVLTIYNLFLWPCFGLIAAIGYAAYRKNKWNIEGKLSYQWHYDLDSDGRARIQANLHCCGYKSFTDYHERSNKCFPRTLLPGCKFKYQTFTKEALTITWIVAFSMVPVHLFVLFSGLLCSNHINRKFGKGLPPKIYRLDYQGIVAGTPTGSSLNLYRDGLQQRH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NAY9</accession>
    <name>A0A1C7NAY9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">JmjC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_05812</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000325">
        <property type="protein sequence ID" value="OBZ86138.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NAY9"/>
    <dbReference type="STRING" id="101091.A0A1C7NAY9"/>
    <dbReference type="InParanoid" id="A0A1C7NAY9"/>
    <dbReference type="OrthoDB" id="298344at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.650">
        <property type="entry name" value="Cupin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003347">
        <property type="entry name" value="JmjC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050910">
        <property type="entry name" value="JMJD6_ArgDemeth/LysHydrox"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12480">
        <property type="entry name" value="ARGININE DEMETHYLASE AND LYSYL-HYDROXYLASE JMJD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12480:SF35">
        <property type="entry name" value="TRANSCRIPTION FACTOR JUMONJI, JMJC DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02373">
        <property type="entry name" value="JmjC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00558">
        <property type="entry name" value="JmjC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51184">
        <property type="entry name" value="JMJC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="JmjC" evidence="2">
        <location>
            <begin position="139"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="636"/>
            <end position="663"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="640"/>
            <end position="653"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ86138.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="663" mass="76943" checksum="8E5AD1BF25205926" modified="2016-11-30" version="1">MTKCHLIDTEKDLPCQYEAATRIDFLDFTSESLRLFVQQHCIERGKPLVVSNMHKSDGWKQDIFDIQKLKEYCGDLEIEVDLRKQNTTKKVKLELGGYLEALQQKYDLEGKAPYVYKKPTIPIDNIYAKDVICPDEYGIALKEFLPEFLLPQGNNDLFTFLPDRFKAENLMCYVGQDMTGTPIHRDLCGTMGHNVMTMASEDAFAEWLIVENQYRDELACLIDPEEDDHQRNFRHKGGNKRQAKRTISDSHHVTKSSFMESDRAWLNYDKILKAKFKVQVIVQRKGDLVIIPSRAYHQVRNHGVSVKIAWNRITSQTLTYAFQDQLPLYHIVNRPEVYKCKAIVMFTLREWNRQLVDLVHDLANQSKWIPILCYGPEFFLESSNQLLDVFLKQVILPELLFDGDDQGIIADAPEEVCTVKCDFCHSDVFCHYYHCDLCDQYDLCLDCYSIGRGCQHITSMQMYKGPESIMNAVKLYLDYVKNINLAFHQEVIPNLSLEVLRNKPSHKFANLATTCRRIERHRRLNPNSFNILHCNHCLATTTVSELGEQGIGLSSIFKRNKCPNALSQTEEDRVNFYTCLECTKKCNLCMPLEVTRGSLRDYDLVYYLHPSHDERNWGGFIDLDVKKTCDIPQILRKTRNTSNRGRNPNQGSDQKLPKRIRQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NBS3</accession>
    <name>A0A1C7NBS3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Protein DENND6B</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">DENND6B</name>
        <name evidence="4" type="ORF">A0J61_07157</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the DENND6 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000468">
        <property type="protein sequence ID" value="OBZ84794.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NBS3"/>
    <dbReference type="InParanoid" id="A0A1C7NBS3"/>
    <dbReference type="OrthoDB" id="10265409at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055037">
        <property type="term" value="C:recycling endosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005085">
        <property type="term" value="F:guanyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024224">
        <property type="entry name" value="DENND6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037516">
        <property type="entry name" value="Tripartite_DENN"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13677">
        <property type="entry name" value="LD41638P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13677:SF0">
        <property type="entry name" value="LD41638P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50211">
        <property type="entry name" value="DENN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UDENN" evidence="3">
        <location>
            <begin position="83"/>
            <end position="530"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="24"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="76"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="24"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OBZ84794.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="539" mass="60674" checksum="DEAD8F73F5224C55" modified="2016-11-30" version="1">MESDITTKPNPLFKHLGQASPALLSSSSLCHDPTSSPSSDTSVPSETDMSEVFDFPIRKQCSTSILQLSNRRLGGSASHPNLVTKDDIHLSPKISRTPSPPFSSTPPSSAGLDITDNDEEPYLTLDPLDLSHFRKWIVGFCVVNFDLEIGQALDYVYPAMDLTDLEQKNIVISILGPAFFDTGQPMLEAACMNIAQWASPEDSRILDLPFLGRLLQVELPSPLEPQLLETTPFDMNKLQPDVQIMASLPIGGLYHHFRDILKDLWLLWELMLLAEPIVIIAPDPCVCSEAVISLVDLINPIPYCGDYRPYFTIQDSDFKSFVTKNKPLSSLVLGVTNPFFNTAVQHWPNIVRVGRQQPRKPDGTLITTHIQSMHPTKTKPGLGTKSNVLFNFVQGVTSKRKSVIARDRELVKMLTEASVRGYPPDWVLNNILRRHFVDLTEKFLVPLNRYFSTLIPVDISIRGEVPRLRPFQTDQFMKSLKEHGPQLPFKSTFKTRTSTSDPTKELYSQFLKCGNFATWLQQRTIRAEAEMLKRRNQAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NBV3</accession>
    <name>A0A1C7NBV3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Cytochrome P450</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">A0J61_05360</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000287">
        <property type="protein sequence ID" value="OBZ86583.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NBV3"/>
    <dbReference type="STRING" id="101091.A0A1C7NBV3"/>
    <dbReference type="InParanoid" id="A0A1C7NBV3"/>
    <dbReference type="OrthoDB" id="1470350at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd11064">
        <property type="entry name" value="CYP86A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24296">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0349">Heme</keyword>
    <keyword evidence="4 5 6" id="KW-0408">Iron</keyword>
    <keyword evidence="2 5 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="3 6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008889606" description="Cytochrome P450" evidence="7">
        <location>
            <begin position="25"/>
            <end position="503"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="5">
        <location>
            <position position="450"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OBZ86583.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="503" mass="57899" checksum="C90966683A142950" modified="2016-11-30" version="1">MPHLTEKSLIAAFFLLACIYNDRAIFDSNRPGIKTKPGWPLVGNLPSLLKNVTRLHDFMLDSCNQLGALTMTMSSLGIPRHIGTLDPKNVEHILKNNFENYIKGPEFHTGMMDLFGNGIFNANGEEWKYQRKTASAIFNVKNFRDQFTIVFVGELEIMSKAIFEEAVDRNQAVDFHETMFKFTLDSFIMLGFGVQLNSILTKGQVPFAHAFDEAQKNTFLRFVNPLWPATERLLGFLMPWKASMRNNLKIVNDFARQVIQERRAQMALGEIHTDLLSRFMNAQNHKGDILSDNELRDIVLNFVVAGRDTTAQALSWTFYMLMHHSRVERKLLEEVDSSILEEDIHQLPVLYEKIKKMTYAHAVFFEVLRLYPSVPLNQKYALKDDVWPDGTAIKQGDYVLWCPYAQGRLEKIWGADAKEFRPERWITSEGELRRESPGQWPAFHAGPRVCLGQQLATLEALIVIAFLLKRYKFTLLPGQDITYQISLTLPMKNGMKVMVERRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NCB9</accession>
    <name>A0A1C7NCB9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">LON peptidase N-terminal domain and RING finger protein 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">LONRF3</name>
        <name evidence="7" type="ORF">A0J61_05189</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000273">
        <property type="protein sequence ID" value="OBZ86762.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NCB9"/>
    <dbReference type="STRING" id="101091.A0A1C7NCB9"/>
    <dbReference type="InParanoid" id="A0A1C7NCB9"/>
    <dbReference type="OrthoDB" id="264917at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.130.40">
        <property type="entry name" value="LON domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003111">
        <property type="entry name" value="Lon_prtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046336">
        <property type="entry name" value="Lon_prtase_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015947">
        <property type="entry name" value="PUA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027370">
        <property type="entry name" value="Znf-RING_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017907">
        <property type="entry name" value="Znf_RING_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23327:SF42">
        <property type="entry name" value="LON PEPTIDASE N-TERMINAL DOMAIN AND RING FINGER PROTEIN C14F5.10C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23327">
        <property type="entry name" value="RING FINGER PROTEIN 127"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02190">
        <property type="entry name" value="LON_substr_bdg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13445">
        <property type="entry name" value="zf-RING_UBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00464">
        <property type="entry name" value="LON"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88697">
        <property type="entry name" value="PUA domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00518">
        <property type="entry name" value="ZF_RING_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="6">
        <location>
            <begin position="6"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="296"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="296"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="331"/>
            <end position="346"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OBZ86762.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="477" mass="54321" checksum="08AA158D3AEF0D9A" modified="2016-11-30" version="1">MTDFQCFKCKQMLVKPTTLSCGYTICMSCLPSQSANQKSVFVCPVNECKKESHLFGPSLYLDDMVDNLMKKNTDQLSTVLQCTIGNHPLSSPVTNHCGHTFCRLCLLMCKISNDQCNQCQKRLPSYQYIQQQPCNYLIEDLLLKQEEQTPLTTTNNLVISFSNLTKTSYHDMPIYLSEFPVLPSQKLRIPIYTENHRQMFLKSLLRCNEYQSLCLAIITRSKQHYNNRFGTIVKIGGIEQRNRDMIVDLVGYDRFQITSVSQQTDTVIMADIEMKFEAQQDLSFIPLDKHHWTEYQTTKPKEAIQQEPEKQHYKRRKIKVNKEVLPPSPNSSSTDDAITTPSTTTPPVSPPREPIDDETHMSTSIKLSNRVHEFISTLARSKPSNSFCSALEGLLGPVWLESVQGLHGPLPAADHAVAMCWWAATVMPVSNTDRYHVLASDSLEDRLIIVLSWISDLESQWGNCRRTAVQTAAKVWQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-09-13" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NCR9</accession>
    <name>A0A1C7NCR9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_05057</name>
        <name evidence="2" type="ORF">A0J61_05059</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000263">
        <property type="protein sequence ID" value="OBZ86887.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="LUGH01000263">
        <property type="protein sequence ID" value="OBZ86893.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NCR9"/>
    <dbReference type="InParanoid" id="A0A1C7NCR9"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="31"/>
            <end position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ86887.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ86893.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="164" mass="18782" checksum="83CDDD589C23CF2A" modified="2016-11-30" version="1">MDTANLQWKRFSVQDLDRYDASPLAQVNEEANNSFNPEDDAETNQPQETTVTVRRYSRDQMHDLNKTTPDEMGSVCGRLVESYLEMGRMERRRWQNHERTLGTTEDPNSTENCAPLPDMMPTTHTIPGIAPANDKTQDEFRDSATYRKYIKVTLGLKTSKHAGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7ND46</accession>
    <name>A0A1C7ND46_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="9">DnaJ subfamily A member 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">DNAJA2</name>
        <name evidence="9" type="ORF">A0J61_04889</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000250">
        <property type="protein sequence ID" value="OBZ87052.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7ND46"/>
    <dbReference type="STRING" id="101091.A0A1C7ND46"/>
    <dbReference type="InParanoid" id="A0A1C7ND46"/>
    <dbReference type="OrthoDB" id="550424at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030544">
        <property type="term" value="F:Hsp70 protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009408">
        <property type="term" value="P:response to heat"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd10747">
        <property type="entry name" value="DnaJ_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd10719">
        <property type="entry name" value="DnaJ_zf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.110:FF:000041">
        <property type="entry name" value="Chaperone protein DNAj, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.10.230.10:FF:000001">
        <property type="entry name" value="DnaJ subfamily A member 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.260.20:FF:000003">
        <property type="entry name" value="DnaJ subfamily A member 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.230.10">
        <property type="entry name" value="Heat shock protein DnaJ, cysteine-rich domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.260.20">
        <property type="entry name" value="Urease metallochaperone UreE, N-terminal domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01152">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012724">
        <property type="entry name" value="DnaJ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002939">
        <property type="entry name" value="DnaJ_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018253">
        <property type="entry name" value="DnaJ_domain_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044713">
        <property type="entry name" value="DNJA1/2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008971">
        <property type="entry name" value="HSP40/DnaJ_pept-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001305">
        <property type="entry name" value="HSP_DnaJ_Cys-rich_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036410">
        <property type="entry name" value="HSP_DnaJ_Cys-rich_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43888">
        <property type="entry name" value="DNAJ-LIKE-2, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01556">
        <property type="entry name" value="DnaJ_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00684">
        <property type="entry name" value="DnaJ_CXXCXGXG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00625">
        <property type="entry name" value="JDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57938">
        <property type="entry name" value="DnaJ/Hsp40 cysteine-rich domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49493">
        <property type="entry name" value="HSP40/DnaJ peptide-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00636">
        <property type="entry name" value="DNAJ_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51188">
        <property type="entry name" value="ZF_CR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 5" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="J" evidence="7">
        <location>
            <begin position="6"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="domain" description="CR-type" evidence="8">
        <location>
            <begin position="141"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="CR-type" evidence="5">
        <location>
            <begin position="141"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="394"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="6">
        <location>
            <begin position="411"/>
            <end position="420"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00546"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51188"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OBZ87052.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="420" mass="46026" checksum="B52660F2339C4165" modified="2016-11-30" version="1">MAIETRYYDILEVSVDASDNEIKKAYRKLAMKYHPDKNPDEGERFKEISHAYEILSDPDARASYDQFGEDGPGGAGGGGFGGMSADDLFANLFGGGGGGGFDFGGGGDFYYGSGGGMPRRPRKGENMKYPLNVTLEDLYLGKRTKLASSKNVICSNCDGKGGKTGATRKCNACKGRGFQVAMRQVGMGMIQQMQVPCQECDHTGEIAKDRCKKCKGKKVTEEKKILEVFIEKGMEDGQRIYMKGEGDQEPGIEPGDVILVLNQKEHAIFTRKGQDLLCKVKISLTEALCGFDKVVVTHLDGRGIHVKHPAGKVIRPGMVKRIPHEGMPTYKRPDNRGDLFIQFDVEFPSDDFATAQQLTQLESILPKRAPVKIQQEIVDECSLMDASLDTFGANQQSRNAYDEDESDEEQGGGGVRCAQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NDF6</accession>
    <name>A0A1C7NDF6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Putative glucosamine 6-phosphate N-acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">MIMI_L316</name>
        <name evidence="4" type="ORF">A0J61_04840</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000246">
        <property type="protein sequence ID" value="OBZ87115.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NDF6"/>
    <dbReference type="STRING" id="101091.A0A1C7NDF6"/>
    <dbReference type="InParanoid" id="A0A1C7NDF6"/>
    <dbReference type="OrthoDB" id="10039976at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016747">
        <property type="term" value="F:acyltransferase activity, transferring groups other than amino-acyl groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04301">
        <property type="entry name" value="NAT_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050832">
        <property type="entry name" value="Bact_Acetyltransf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43877">
        <property type="entry name" value="AMINOALKYLPHOSPHONATE N-ACETYLTRANSFERASE-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="3">
        <location>
            <begin position="2"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OBZ87115.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="142" mass="16012" checksum="D205C8CFC0AD518C" modified="2016-11-30" version="1">MYTIRQLEQEETTDTSISELYKLLSQLSSSVTKVAIWEAIGSEQNHILIATTTDGKLVGTATMAYLRCLTGTRVHIEDVVVDQAHRGKGIATLLLTEIIQRAKELKAKSIDLTSRPDKIAANQLYRKLGFVQRETNVYRYQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NDF7</accession>
    <name>A0A1C7NDF7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Ion transport domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_04834</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000246">
        <property type="protein sequence ID" value="OBZ87111.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NDF7"/>
    <dbReference type="STRING" id="101091.A0A1C7NDF7"/>
    <dbReference type="InParanoid" id="A0A1C7NDF7"/>
    <dbReference type="OrthoDB" id="301415at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="373"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="440"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="475"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="513"/>
            <end position="539"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="574"/>
            <end position="602"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="623"/>
            <end position="645"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="665"/>
            <end position="689"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="102"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="115"/>
            <end position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ87111.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="706" mass="79429" checksum="F7DA0855CD554699" modified="2016-11-30" version="1">MSDNPPGSPIPNHSGSTETTRLLATSTATTTYATTNGQGNSTVITMQTEETNKLNGHHQVMSKDKFEQIVTSGQPTLPADQLTEKIQDILVFSEIKRKQERKRALQKKKEAIVPNNDNSSSSSSSSSSSSSSDDDDSPRHTLKKKLSEWSIAGSHHEDTPGKKKRLRRRDLAVDALKLATDRWKEKHGWSTSHPAQAEQTHVIATNSSTVVQQETLKLPSQAESIYEVAKHASVCAVLALLHERKLSGAPSEADVSLQFLALSTLNLGLKAKETSVSHVVLYAMLKTKWIDGKSALELAYENDSQIFLKDARVQLVIEELWKSGPNWREDPNHPCSIWTKGSKPTIDTSKNFSWYVMKNTFTDFLARWCSARYQLWIGAISTLMYLAFHLATLTNRDYISSDTPDVYEYVYYYLVLSDLFLESVKLLTSPCAYLKKLSSYVSFVTAALLTASLVIRLFTLAAVDSLEDAVDLLTLSFQLIVLATPLLFLRLFYATSDAHWLLAKAEYIVHQCLINSLWVFVVGLGAMVGFWVALAALQFDDVRPMAMLRFLLLGALHAPEIGDTLYYQPQTAGFLLIVYLFMTVVVLGSLLTASFLSTFIDISRRMDQVKRGWAIRRCLVTKPAFHMFLPSALVDVVFRIVHWFLCSVCKCRQESTVWLEKTHQVIWYLVYSPIILIVGLYELLSLLIMKWSLVRQAFQRNTVVIQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NDJ7</accession>
    <name>A0A1C7NDJ7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Putative mediator of RNA polymerase II transcription subunit 27</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">med27</name>
        <name evidence="7" type="ORF">A0J61_04798</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the Mediator complex subunit 27 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000242">
        <property type="protein sequence ID" value="OBZ87161.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NDJ7"/>
    <dbReference type="InParanoid" id="A0A1C7NDJ7"/>
    <dbReference type="OrthoDB" id="1868004at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016592">
        <property type="term" value="C:mediator complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003713">
        <property type="term" value="F:transcription coactivator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021627">
        <property type="entry name" value="Mediator_Med27"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13130">
        <property type="entry name" value="34 KDA TRANSCRIPTIONAL CO-ACTIVATOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13130:SF4">
        <property type="entry name" value="MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11571">
        <property type="entry name" value="Med27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="58"/>
            <end position="117"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OBZ87161.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="333" mass="38952" checksum="8FCD177933F46CF5" modified="2016-11-30" version="1">MSSTIPPRTTEKIEEDIVRIDHALLTVSEIRSSLHTFTELVQSEQKGPNFVYSLTDRLKTLRRELSTLLAESENLKGALEYAQVKANENNFNWDLIRNDAEKEAVEEETRYREEDSRKAKEVGSLVKSNADYAYNQLSSIVLDRPANLNRSDSFFTNHVEAWLKQKPESIEFSVLFTVPERPTLAGSTCSIKVFSRKSVVADLELEYDKTSDTLIVHQYDIKSVKEQKHFWQDSQYLVFQKLKLLATSAFEDMLAYFAKDSLYHVLNWFASYHDLFTRPCQRCHKLLQFDSPQYKYLPPMVRTWPKRTLDDSEQPLNVAYHMRCFTEYKNTRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NEQ0</accession>
    <name>A0A1C7NEQ0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Chitin synthase export chaperone</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">chs7</name>
        <name evidence="14" type="ORF">A0J61_04916</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Endoplasmic reticulum membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the CHS7 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000252">
        <property type="protein sequence ID" value="OBZ87036.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NEQ0"/>
    <dbReference type="STRING" id="101091.A0A1C7NEQ0"/>
    <dbReference type="InParanoid" id="A0A1C7NEQ0"/>
    <dbReference type="OrthoDB" id="2189463at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022057">
        <property type="entry name" value="Chs7"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35329">
        <property type="entry name" value="CHITIN SYNTHASE EXPORT CHAPERONE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35329:SF2">
        <property type="entry name" value="CHITIN SYNTHASE EXPORT CHAPERONE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12271">
        <property type="entry name" value="Chs7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="7" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="10 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0653">Protein transport</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 13" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="50"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="86"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="117"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="160"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="189"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="224"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="257"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="308"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="317"/>
            <end position="329"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004586"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00018354"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="OBZ87036.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="335" mass="38182" checksum="7B43E1BD17993352" modified="2016-11-30" version="1">MSSTITYYFEPLNFNGICRSLALDLCPLIGQHDGIEPVCYSRNVELSGNIIFQPSTLIIDVVAIIMTMIMIYHIRSKYTAVGRQEIVMFFYMYMLTTLLDMLLVTGIIPISSAPYPWFTAIHIGLTCATYWCLLLNGFVGFQFAEDGTPLSLWSIRISSFIWFIVTGFLAIATFKGVAGLSYTSQGPLWIFYLVLNWLMFFIYIISQIILVINTLDDRWPLGDILFAAAFFAIGQVLLYVFSVIICENTKHYVDGMFFGAICNLLTVMMIYKYWDSITKEDLEFSVGSKQNVWEVKELLGDDELSQSYNSYQQSPSATTPSTAPQNYQPYEQHPY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NFB3</accession>
    <name>A0A1C7NFB3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">small monomeric GTPase</fullName>
            <ecNumber evidence="2">3.6.5.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">RAB18</name>
        <name evidence="11" type="ORF">A0J61_04156</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>GTP + H2O = GDP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:19669"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58189"/>
            <dbReference type="EC" id="3.6.5.2"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="10">
            <dbReference type="Rhea" id="RHEA:19670"/>
        </physiologicalReaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the small GTPase superfamily. Rab family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.5.2" evidence="2"/>
    <dbReference type="EMBL" id="LUGH01000197">
        <property type="protein sequence ID" value="OBZ87792.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NFB3"/>
    <dbReference type="InParanoid" id="A0A1C7NFB3"/>
    <dbReference type="OrthoDB" id="9989112at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003925">
        <property type="term" value="F:G protein activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01863">
        <property type="entry name" value="Rab18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000430">
        <property type="entry name" value="Probable Ras-related protein Rab-18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050227">
        <property type="entry name" value="Rab"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001806">
        <property type="entry name" value="Small_GTPase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47977">
        <property type="entry name" value="RAS-RELATED PROTEIN RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00071">
        <property type="entry name" value="Ras"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00449">
        <property type="entry name" value="RASTRNSFRMNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00175">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00176">
        <property type="entry name" value="RAN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00173">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00174">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51417">
        <property type="entry name" value="ARF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51419">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51421">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51420">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-0636">Prenylation</keyword>
    <keyword evidence="6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023289"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00047660"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="OBZ87792.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="204" mass="22920" checksum="5D078E786EB9FEB3" modified="2016-11-30" version="1">MSQQIPTLKLLLIGNSNVGKSSLLLRFTDDTFLPQEEVSATIGVDFKVSMMEVDGTMYKLTIWDTAGQERFRTLTSSYYRGAQGVILVYDVSNRETFDAXNTWWNEVNTYCSSPNVVKMIVGNKVDKESARVVSYEEGANFARKLSTLFVECSAKTRVGVKQAFEELVEKIIETPSLWQKDASRSTVKMTTEDQTSPSNDYCAC</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NFD0</accession>
    <name>A0A1C7NFD0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="13">ATPase WRNIP1 C26H5.02c</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">A0J61_04694</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000235">
        <property type="protein sequence ID" value="OBZ87256.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NFD0"/>
    <dbReference type="FunCoup" id="A0A1C7NFD0">
        <property type="interactions" value="791"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NFD0"/>
    <dbReference type="InParanoid" id="A0A1C7NFD0"/>
    <dbReference type="OrthoDB" id="10265467at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008047">
        <property type="term" value="F:enzyme activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051880">
        <property type="term" value="F:G-quadruplex DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017116">
        <property type="term" value="F:single-stranded DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051276">
        <property type="term" value="P:chromosome organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033567">
        <property type="term" value="P:DNA replication, Okazaki fragment processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000731">
        <property type="term" value="P:DNA synthesis involved in DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006282">
        <property type="term" value="P:regulation of DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd00009">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18139">
        <property type="entry name" value="HLD_clamp_RarA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.272.10:FF:000001">
        <property type="entry name" value="Putative AAA family ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000137">
        <property type="entry name" value="Replication-associated recombination protein A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.272.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3710.10">
        <property type="entry name" value="DNA polymerase III clamp loader subunits, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032423">
        <property type="entry name" value="AAA_assoc_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051314">
        <property type="entry name" value="AAA_ATPase_RarA/MGS1/WRNIP1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008921">
        <property type="entry name" value="DNA_pol3_clamp-load_cplx_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021886">
        <property type="entry name" value="MgsA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006642">
        <property type="entry name" value="Rad18_UBZ4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13779:SF7">
        <property type="entry name" value="ATPASE WRNIP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13779">
        <property type="entry name" value="WERNER HELICASE-INTERACTING PROTEIN 1 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16193">
        <property type="entry name" value="AAA_assoc_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12002">
        <property type="entry name" value="MgsA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00734">
        <property type="entry name" value="ZnF_Rad18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48019">
        <property type="entry name" value="post-AAA+ oligomerization domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51908">
        <property type="entry name" value="ZF_UBZ4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 10" id="KW-0227">DNA damage</keyword>
    <keyword evidence="9 10" id="KW-0234">DNA repair</keyword>
    <keyword evidence="2" id="KW-0235">DNA replication</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <keyword evidence="6 10" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="UBZ4-type" evidence="12">
        <location>
            <begin position="3"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="39"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="42"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008959"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01256"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51908"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="OBZ87256.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="477" mass="53760" checksum="6DA5F5A96DC90F7A" modified="2016-11-30" version="1">MDKVECPICHQWVPSADINVHIDANCPSSDTTKLAPLFNKKPLQEKPKQEKLPQETLKRSHSSTFQTDAPIKKKKPDPLDSMPLAAKVRPTHMDDFVGQESLLGPDGILKKLIDHDRIPSMILWGPPGCGKTTIARIISNMSRSRFVELSATTHHTADVKKAFDEAKNHQALTGQKTILFLDEIHRFTKAQQDIFLPYVEHGTIHLIGATTENPSFKVNSALLSRCKVFVLERLDQQHIQTILSRALVRWRGKEEAEEEQLALEQLAAFSDGDARAALNTLEMALSLLPTKEDLLNQEVVKNAFQKSHLLYDRNGDQHYDIISALHKSIRGSDPDAALYWLGRMLQAGEDPLYIARRLVRCASEDIGLADNTALPLAMSAYHACEKIGMPECDTILAHVVVHLAETKKSVRTYKAYHRVKQFIQDNPSYPVPMHIRNAPTSLMKDLGYGKDYIYNPDHEGPVDQTYLPSEMQQVRFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NG15</accession>
    <name>A0A1C7NG15_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Ricin B lectin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_03890</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000178">
        <property type="protein sequence ID" value="OBZ88057.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NG15"/>
    <dbReference type="InParanoid" id="A0A1C7NG15"/>
    <dbReference type="OrthoDB" id="40579at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030496">
        <property type="term" value="C:midbody"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008017">
        <property type="term" value="F:microtubule binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902412">
        <property type="term" value="P:regulation of mitotic cytokinesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd23454">
        <property type="entry name" value="beta-trefoil_Ricin_GllA-1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.80.10.50">
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.240">
        <property type="entry name" value="Putative phosphatase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043188">
        <property type="entry name" value="DCDC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023198">
        <property type="entry name" value="PGP-like_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035992">
        <property type="entry name" value="Ricin_B-like_lectins"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000772">
        <property type="entry name" value="Ricin_B_lectin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46302">
        <property type="entry name" value="DOUBLECORTIN DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46302:SF3">
        <property type="entry name" value="DOUBLECORTIN DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00652">
        <property type="entry name" value="Ricin_B_lectin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14200">
        <property type="entry name" value="RicinB_lectin_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00458">
        <property type="entry name" value="RICIN"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50370">
        <property type="entry name" value="Ricin B-like lectins"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50231">
        <property type="entry name" value="RICIN_B_LECTIN"/>
        <property type="match status" value="7"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ricin B lectin" evidence="2">
        <location>
            <begin position="11"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="domain" description="Ricin B lectin" evidence="2">
        <location>
            <begin position="221"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="domain" description="Ricin B lectin" evidence="2">
        <location>
            <begin position="424"/>
            <end position="619"/>
        </location>
    </feature>
    <feature type="domain" description="Ricin B lectin" evidence="2">
        <location>
            <begin position="878"/>
            <end position="1014"/>
        </location>
    </feature>
    <feature type="domain" description="Ricin B lectin" evidence="2">
        <location>
            <begin position="1423"/>
            <end position="1567"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="190"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1245"/>
            <end position="1300"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1361"/>
            <end position="1393"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="194"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1259"/>
            <end position="1284"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1287"/>
            <end position="1300"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1371"/>
            <end position="1388"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00458"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ88057.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="2904" mass="325853" checksum="B69F1A80E1095357" modified="2016-11-30" version="1">MFEKSEKFPEGWFFIKNHSNGYVLMVDNESHETGAHVVLSSLRTKDYSAQLWRYDPNGYIVNKKSGQAMDVAKGSAKAGVDIVQQILSHDAKAQNNYQKFGLSPYGHIFLTQKPDLVLGIKESFFSRREGLHVHLQLVDKRHLDRKEQRWDFVLPVVKEVHEPLKRSISTKSTSSASVKVPAVIQIKDDDTRSVHSNAESTNSGIDHSEANTVPVGSFPETAFFLKSDVAGLYISVENASSVSAGTQLTLENIRKKNYDSQIWTYDANTHRIVNKHSGLVLGVSHSSIKDGATIVQAASSTSNEKAQAWIMSPEGEIALKHDSGYVIGFKESWFGSREGAHLYLQKRSKSSANQKFTVVLPVFKKSTETNVKTETRGVFPEGWFFVKSQARGLVLTVLETGVISAEVAASKLDKGNYSRQLWKFDSGFIVNKASEMVLDVRGGSLKSGAGICQYTRKEKDNENQQWALTPEGSIFIQANKNLVLTVKENETVRSKLYLSERKPGHKEQCWNFVLPVFRKKQTTTVTKTTIRYAAYPAGWFFIRSYCDNSTTEAPLVLTSHEKSITLSLLDKENWHQQLWTFSSGKLINYATDLAIDVNTYAAGGQLIQSKSTAQKWYMTTDGYLFYGSSDAKLALLAETEDGKCRLSLSEFKASRDFRWGLLLPKFVYRSGVQLLTHWSIAFLKEWGGSDANTSETNTQSVAEWPEGEFYIGGPDDRALAPEKLEDGSRLVMKTLSIEQSKDFRWTVRGSHLVHCATGLMMRVKDNFTEGTHLILSSESKDDIHQLWTLRMNGSIVSKANERFGLSFIQSNGAWIVQITTTLHYSWRILYGKYEMQNNQQSSRLIGFRRFVLVACAFHNHANVERKLVTHSYGVFPKGWVFIRSKIDSGLYITVSDKKKGAKLILSKLDFKSFRRQLWRYREDGCIVNFDTDYVIDVAGGKLSSNANIIQWSPKFLLQSRKNQVWSLSTEGHIHPQSNSSLVLSPSDSKIKENVELKLIKCDSAALGYQQWTFATPVFSTSTHTTHAAQQAHKDTLTLEKVGDSCSVDVSSTERYERVNKRIIIRRWGVFPDGSFFIRCAYGDKHMALTVEQNEAGLYQVVIRSLNFKEYKWQLWTFKDGHLINEQTGLVLDAQPSEDTVIEDEQPQVYLKPKALNVGQFWDLGVDGEIHLRSNEKLVIGVLNVGDASREGAKVGIRKTRIVRTNVGARELISLKSEQWLRWTFTKPVFGKRIITTTTKDEATMEIEKTEDQTVVVKEQDEEIDDDEEEESNEQEVDDGEESEYEIQTPTQTPSSSTTTSNSALGVSVVVAGAAINVAAGEAVNIISKSKETEKGSTVAQITALDSEVRTDMIATVETLAGSESSFSEPASPIISPKISPQKSSSSKSQRLHRKDSFQLEEDYVPTGFEKIARFKTHHGNFPKGYFFIKNSLHGFVLGVVGDVKDGAYLALTKMKSSDYADQLWSYRNERLVNLKDDSLVLDAAKADLVAGERVHLSIXNSLNQEDEDQTWEHNPEGFIHLKSRSSFVLSLKETKRSDKLNQIDVFVQEAKSLVKKQARPEQHWEVLVPALIPVSQGESGVKIVESGKVDKITSSASAIVAYKWLKETYCHKITVEDQWPETQGWFFIRYGTEKHFIASGETAQSQVGVYELSENIDHRRFLWAVIDNYLINYKYMLRLILNTSQKWVLSSSRNTLNQKFHISINGSISIRTSKTIYYMRLIRKSSKSFDLSVTSDTDCLEAHGFEIHIPVISDVEHQKDAITAFNSANRWICKQKSDWSTLNIATSRRGVFPPSTWFFMKVVSEGSDSLVLSTQPENSQLILKKLDFQSFRNQLWTFNNGLLINYGSKLVIDVEGNVSASSKIVHKAEAGVSTQKWFLTTDGHIELDSHDYFTIGTKKIADGAEVLLGSTKNFGSVKSIHWKFSTPIFGKKTTSGSTISTDLGLTKALEDGAIISGTKDVTSNDGISQLVSTPFTKHYIVICRDIYLIVNWWKIVFARRLTLCQTKQEYLEVSEEYRRILRSRLVRYVEIHGSALTAGDRLGLEHIIEKTQGILEEQVFEKIKELPEHNNQIDANQLNLSKLVSNASNTIEEEFKGAQKLTASESTVVSANTDELVTFYDKLHDAIQTQVTTVKTTVQDKFTEGGDAITKVDFTTTKDDFQKVVGKKLTXAKTDVIETVKTGALKGTESVTVDVVVEEVETDKVTVVVGGENEGLLVNKPTRVQVIEKSSGSIEVVASKLPASTNDSTSVGLGNIIVTKDAHNYTSEVCSSFDNATRHTYDWFVRFIEKVTCMLEVGENYAEIESVITEEEENIRCTLQNFKHQLSLSKSQTVIKNSGQWGLFYDELSHVIASQITPLKETIKESYDNGQDTIYSYSINIQTTKDAFRKAIDLHTSQSKVKVYESAKANVMEIQVGQNIDEHEIVIDVINPPKEVIQGEVVYTSSETAQTTTKKTLSIPMLETQNYLNVWYDVFXKKIHAIISSKSGVSVDYQKEVEITINDSLKEVELVFNNTKSSLRYNYVTTNECSADVSTLVENSQKLSVDSLNAVYAIIVEQTSLVKKAVLSDNDQSALEKITLIERHSKQKAIDLLNTSIETAVSAGFEGKTVTWIKTAQIPSSFKDVKVFAFDLIDTVVDYRTTVVKAWYALMAKKQDSYRFTAIDVEAFVIRWYYLYLEERIKAKYSESDAAILLIALKLVLVEFELQISAFTKEELADMCSVWLNLELFDDSSSSIRKIKQLDGVYTVAISHAFTIRTMMNLARAGCLCWHAQFTADMFAACTINNGTSTEVTVVSNTAMLLGLNNACELAVVSSNPKVLEAAQANGCKTVALDRFGDLRKNAYSFDVEFDALDIFAESFHIFYESKTASKTIEAPVTQTWFQRVISSVSEAAESISQTVINQI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NG85</accession>
    <name>A0A1C7NG85_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">DnaJ subfamily B member 8</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">Dnajb8</name>
        <name evidence="3" type="ORF">A0J61_03960</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000183">
        <property type="protein sequence ID" value="OBZ87990.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NG85"/>
    <dbReference type="STRING" id="101091.A0A1C7NG85"/>
    <dbReference type="InParanoid" id="A0A1C7NG85"/>
    <dbReference type="OrthoDB" id="10250354at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044183">
        <property type="term" value="F:protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051087">
        <property type="term" value="F:protein-folding chaperone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018253">
        <property type="entry name" value="DnaJ_domain_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43948">
        <property type="entry name" value="DNAJ HOMOLOG SUBFAMILY B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43948:SF10">
        <property type="entry name" value="MRJ, ISOFORM E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00625">
        <property type="entry name" value="JDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00636">
        <property type="entry name" value="DNAJ_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="J" evidence="2">
        <location>
            <begin position="7"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="156"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="167"/>
            <end position="177"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ87990.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="326" mass="38288" checksum="4539BB1A7CA44A66" modified="2016-11-30" version="1">MSTTALDYYQILNVPPDSNEQEIKKAYRKLALKYHPDKNSSADASEKFKAISEAYEILSDPEKRRIYDNRDNIEYNNNHNHNEFHNPFAGFAFHSPEEIFAQVFNHFHSFGYGGVSDMFPPFMMDRPPARMSSGFPFATNTRNMMDNFFDPSPMFGHMSSSSSTSSRPHQQGFSSKSVTTTTRTVNGVVQTVRVTRITDEHGTKVIEEEYDNGAPRIKQEPVKQINNTYYGENNQDNTIINRSSQMQQQQQQNQHDQERAYQERMMHGAEQHHLLHQQQMAWNHQHTMQRQQDMHRRMLEQQQRMFQSHFNNTNNSNGYYYNPHLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NGF8</accession>
    <name>A0A1C7NGF8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Serine/arginine-rich splicing factor 4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">Srsf4</name>
        <name evidence="5" type="ORF">A0J61_03764</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000169">
        <property type="protein sequence ID" value="OBZ88182.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NGF8"/>
    <dbReference type="FunCoup" id="A0A1C7NGF8">
        <property type="interactions" value="513"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NGF8"/>
    <dbReference type="InParanoid" id="A0A1C7NGF8"/>
    <dbReference type="OrthoDB" id="1099063at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd12339">
        <property type="entry name" value="RRM2_SRSF1_4_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050374">
        <property type="entry name" value="RRT5_SRSF_SR"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23003">
        <property type="entry name" value="RNA RECOGNITION MOTIF RRM DOMAIN CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23003:SF51">
        <property type="entry name" value="SERINE-ARGININE PROTEIN 55"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="4">
        <location>
            <begin position="4"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="4">
        <location>
            <begin position="94"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="161"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="169"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="201"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="230"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="259"/>
            <end position="269"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OBZ88182.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="269" mass="31623" checksum="A3C68C2D4D4A65DC" modified="2016-11-30" version="1">MSSTRVYIGRLARDATKRDLERLFKGYGDIREINVKTGFGFVEFSNERDAKDVVYDFHGKSFLGERLIVEIARGARRTDDRRNNGGNDRRRSHYRLIVENIAPGTNWQDLKDMMRKAGEVTFADISRDRPSEGIVEFAIRDDMEYALKKLNDRELNGQRVTLREDVGRSSRRRSRSRSKSRSRSPPRRRRRSPSEESRSRSPPRRRRRSPSHSRSRSPSRSRSPPRKRDKRESSDREDSRDRRRAKSESRSRSRSRSPARSEESPARED</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NGI4</accession>
    <name>A0A1C7NGI4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_05462</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000295">
        <property type="protein sequence ID" value="OBZ86484.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NGI4"/>
    <dbReference type="InParanoid" id="A0A1C7NGI4"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="43"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="43"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ86484.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="80" mass="8870" checksum="0B96BFF236514597" modified="2016-11-30" version="1">MPRQEATLRETKQRKEKVEESSRGQTEAIVTDNNLKSLQITPALSGTSEDCRPSFNTASAKSDVADTGNELTLMQQAYEH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NH01</accession>
    <name>A0A1C7NH01_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">ATP-dependent RNA helicase SUB2</fullName>
            <ecNumber evidence="2">3.6.4.13</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="14">ATP-dependent RNA helicase sub2</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="21" type="primary">uap56_1</name>
        <name evidence="21" type="ORF">A0J61_04120</name>
    </gene>
    <organism evidence="21 22">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="21 22" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="21 22">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">ATP-binding RNA helicase involved in transcription elongation and required for the export of mRNA out of the nucleus. SUB2 also plays a role in pre-mRNA splicing and spliceosome assembly. May be involved in rDNA and telomeric silencing, and maintenance of genome integrity.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="15">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.13"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="12">Belongs to the DEAD box helicase family. DECD subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="21">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.13" evidence="2"/>
    <dbReference type="EMBL" id="LUGH01000194">
        <property type="protein sequence ID" value="OBZ87826.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NH01"/>
    <dbReference type="FunCoup" id="A0A1C7NH01">
        <property type="interactions" value="932"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NH01"/>
    <dbReference type="InParanoid" id="A0A1C7NH01"/>
    <dbReference type="OrthoDB" id="10265785at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005681">
        <property type="term" value="C:spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051028">
        <property type="term" value="P:mRNA transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008380">
        <property type="term" value="P:RNA splicing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd17950">
        <property type="entry name" value="DEADc_DDX39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18787">
        <property type="entry name" value="SF2_C_DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000111">
        <property type="entry name" value="DEAD-box ATP-dependent RNA helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000168">
        <property type="entry name" value="DEAD-box ATP-dependent RNA helicase 56-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014014">
        <property type="entry name" value="RNA_helicase_DEAD_Q_motif"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47958">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE DBP3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51195">
        <property type="entry name" value="Q_MOTIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 21" id="KW-0347">Helicase</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="9" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="7" id="KW-0509">mRNA transport</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="22" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0747">Spliceosome</keyword>
    <keyword evidence="7" id="KW-0813">Transport</keyword>
    <feature type="domain" description="DEAD-box RNA helicase Q" evidence="20">
        <location>
            <begin position="53"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="18">
        <location>
            <begin position="84"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="19">
        <location>
            <begin position="271"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="1"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Q motif" evidence="16">
        <location>
            <begin position="53"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="17">
        <location>
            <begin position="10"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="17">
        <location>
            <begin position="20"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022816"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00037698"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00038213"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00040177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00040402"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00047984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="PROSITE" id="PS51195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="EMBL" id="OBZ87826.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="436" mass="49884" checksum="8326BB137F307DB1" modified="2016-11-30" version="1">MSAVDHADDLIDYEEEDEQTLQQEAAAQQTDSLAVDEDDKKDKKGSYVGIHSTGFRDFLLKPELLRSIVDCGFEHPSEVQQECIPQSILGMDVLCQAKSGMGKTAVFVLATLQQLEPTNGEVSVIVLCHTRELAFQIKNEYARFSKYLPDIRTEVFYGGVPMTKDVEILKDKTRCPHILVGTPGRVLALVRDKHLKLSGVKHFVLDECDKMLEQLDMRRDVQDIFRATPHHKQVMMFSATLAKEMRPVCKKFMQNPLEIYVDDEAKLTLHGLQQFYIKLEEREKNRKLNDLLDTLEFNQVCIFVRSVNRANELNRILSDCNFPSICIHSQMTQEERIKRYKSFKDFEKRIMVATDIFGRGIDIERVNIVINYDMPSSADSYLHRVGRAGRFGTKGLGITFVSNEEDTAILNDVQGRFEVNISPLPEEVDINTYMTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NH02</accession>
    <name>A0A1C7NH02_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Glycosyltransferase-like protein LARGE2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">GYLTL1B_0</name>
        <name evidence="8" type="ORF">A0J61_03569</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000156">
        <property type="protein sequence ID" value="OBZ88377.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NH02"/>
    <dbReference type="STRING" id="101091.A0A1C7NH02"/>
    <dbReference type="InParanoid" id="A0A1C7NH02"/>
    <dbReference type="OrthoDB" id="3056235at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015020">
        <property type="term" value="F:glucuronosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042285">
        <property type="term" value="F:xylosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035269">
        <property type="term" value="P:protein O-linked glycosylation via mannose"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051292">
        <property type="entry name" value="Xyl/GlcA_transferase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12270:SF25">
        <property type="entry name" value="GLYCOSYLTRANSFERASE-LIKE PROTEIN LARGE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12270">
        <property type="entry name" value="GLYCOSYLTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13896">
        <property type="entry name" value="Glyco_transf_49"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0735">Signal-anchor</keyword>
    <keyword evidence="8" id="KW-0808">Transferase</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="60"/>
            <end position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004606"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OBZ88377.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="460" mass="52251" checksum="8B18444565BFCADF" modified="2016-11-30" version="1">MDASLKKGKGEKNFGGNVMHQVNGLFDKFLSPQQTSVLPVQATQKPSSSLLQSRWFRLSVVFYIVFCILMASAHFSAWILFKGKQGFTSIDRLELERTYDADAAYSLMSTMTPGLKFSKLFSKAQYDALKYTQPFWQKAAQVPEPSQVTFIVTTTPKTWKDLTQFAKHWNGPVSATLHIASTQKQQLKTILAEYQSTPELFDHVDLHLVETPQGIEKTASILIPLNVERNLARVFARSNHVSDIPVHTLIATNIQQTLLKHAAEYTELLRRGDMLVIPTFAYNEHAHIAARVPQTKKELVGLVENEKVLGLYDGRFALNGGPTDFEAWKIADDLYKVTQYTMEYEPIVIQSKTVQPWCSERFMDKRSACLLSSYLAGNDFYVLPNDFAVQKPNNQGTAVSDLDSVIEKRLYAKFYWEQCVYHGRQLDALGLWNSLKSNHIRQQCSRIIQNWGRGLIGKPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NHP5</accession>
    <name>A0A1C7NHP5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein C3H8.05c</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">A0J61_03431</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000147">
        <property type="protein sequence ID" value="OBZ88528.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NHP5"/>
    <dbReference type="FunCoup" id="A0A1C7NHP5">
        <property type="interactions" value="186"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NHP5"/>
    <dbReference type="InParanoid" id="A0A1C7NHP5"/>
    <dbReference type="OrthoDB" id="20774at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018846">
        <property type="entry name" value="Beta-prop_RSE1/DDB1/CPSF1_1st"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050358">
        <property type="entry name" value="RSE1/DDB1/CFT1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004871">
        <property type="entry name" value="RSE1/DDB1/CPSF1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10644">
        <property type="entry name" value="DNA REPAIR/RNA PROCESSING CPSF FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10433">
        <property type="entry name" value="Beta-prop_RSE1_1st"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03178">
        <property type="entry name" value="CPSF_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69322">
        <property type="entry name" value="Tricorn protease domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RSE1/DDB1/CPSF1 first beta-propeller" evidence="4">
        <location>
            <begin position="13"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="domain" description="RSE1/DDB1/CPSF1 C-terminal" evidence="3">
        <location>
            <begin position="862"/>
            <end position="1220"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF03178"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF10433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OBZ88528.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="1280" mass="142721" checksum="A9C9772A1F1DBFB0" modified="2016-11-30" version="1">MFAYYRTSSYSTVINRVLRGSITSADPSDLVLVKGNSFAWFRIGSVTENNPTLLEEQLEQSTFGIISDARLLPCNFQSSEKDHVVLDLDRLSIPYAKHTRHHSIIEGEDVIIALSDYGKLVFLTIISDMDQQVNRFETLAEIYLESPGIEYTKLSKKLAVDPHGRAIAVASFQDRFDIFIMNKSLSRVHFDPVIGRGSEYEQGIIWHMEFLYTKEDSMDRILLVLVVYNDVEKLCRLNLYAIDASDVENVTIEKASRLPLEKNTPLPVLLVPLKFQPEAFILVTEQQVCLLTADDLACGNVLYPTSIIPRPFGSTECSLFTAFASHLDTSKSFVYLGAAEGCLFKLHVHSSTELIWEAVQSVPSVGQAMCMLGTIDIIDQHTNSDNDTHVQLQADLVLVAGESTDHLVLAIPCNASDQMIQHATIQSFVNRAPLTDFQVAYGYRHQQDALIACSGQGDHGALSIITFGIETTALSTSDKPEWRGISQCWNIMSEADHASLLIASSLLDTRILTAKEGHVSDATTKIKIRHDVETLHAASLDTQQCHFLLQVHFQGISIICLDNLEPLAWKPKTEADFNIIFATSCKQDNSILVALCVTYGDVFQIQMIDISYKDKDIQSWDNLVFQERSKRIIQSCPSYFGFLELQSCFILTIGAFDSSLVFYSTELHLIQEIDLACSSAKECSIPNSVAILKSAHSTKPIYLIVGLRQGDLLSFKVNDGLLMEEVLVQKKQPYLHAIGSQTVKLFSCSRNGIYALSEQLWRLTCSDKDCIELEQVLLPRFQRSIDTIACFDADMPLLRQTGNPLAVFADDKLHMFQLNLESKINTNKIQLGQTPRKVLYDKALSYLVVTTTTIEVGKRKNYMQLLDPSSGESLSNLESLDLDLDYSQNSMVLSMAEWTLKNNSKTYKYLCIGLGHTEEETRFSKLAKQLKPKKETGSLILFRLKAKRGNSSSFSIKRIWTLEKLSGGVHSVCPHSAGLLFSAGCHLYLYRLDTVTGKLIEIAHKHLLSTITSIHGDGERICVTSHNNESIAFFGLDDERGKLVFIKSDSAFRSIHHSLVIDQQLAIGVSQSGGMVALYDSSESPYEERLDCLFSFHYSDTLVSPSLALLGTQSDAFYDQTKLFISHVLPWSLDIGTSNSQQTGDAIKPIVTGTIAGGIVHVYRISLQLHLLLVALQDLLLSFEPTKPLLGSPDDFANYYCQLSGGEKATIHGDLVEMFLRLSFDEQLRLVSMADDQINQSLDNALSLFINEDAENKQAFTVDHAVELIKDILIGFLSCK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NIY8</accession>
    <name>A0A1C7NIY8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Breast carcinoma-amplified sequence 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">Bcas3</name>
        <name evidence="5" type="ORF">A0J61_02847</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Preautophagosomal structure</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000113">
        <property type="protein sequence ID" value="OBZ89112.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NIY8"/>
    <dbReference type="STRING" id="101091.A0A1C7NIY8"/>
    <dbReference type="InParanoid" id="A0A1C7NIY8"/>
    <dbReference type="OrthoDB" id="25778at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000407">
        <property type="term" value="C:phagophore assembly site"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006914">
        <property type="term" value="P:autophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042594">
        <property type="term" value="P:response to starvation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045142">
        <property type="entry name" value="BCAS3-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022175">
        <property type="entry name" value="BCAS3_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048382">
        <property type="entry name" value="BCAS3_WD40"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13268:SF0">
        <property type="entry name" value="BCAS3 MICROTUBULE ASSOCIATED CELL MIGRATION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13268">
        <property type="entry name" value="BREAST CARCINOMA AMPLIFIED SEQUENCE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12490">
        <property type="entry name" value="BCAS3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21034">
        <property type="entry name" value="BCAS3_WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BCAS3 WD40" evidence="4">
        <location>
            <begin position="393"/>
            <end position="574"/>
        </location>
    </feature>
    <feature type="domain" description="BCAS3" evidence="3">
        <location>
            <begin position="732"/>
            <end position="842"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="321"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="617"/>
            <end position="644"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="759"/>
            <end position="802"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1048"/>
            <end position="1067"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="321"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="621"/>
            <end position="642"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="762"/>
            <end position="771"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="1057"/>
            <end position="1067"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF12490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF21034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OBZ89112.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="1067" mass="118739" checksum="79A3272347ACB298" modified="2016-11-30" version="1" fragment="single">HLTMDSGVRAEPKFLRDPTSLESISSGISKLSNYVASNLPRRKSSHIMTSPFDLYYQQQQQQQMIDTMAEDNALPSQPHEDLEEMDTITFGIFDRLEHKDRHISCLLLGYQDGFQIWDITNPDNVHEICSVRDKDAFGTVSLMHIIQSTQTVAIVSTLEDTKKSRLLFYSLKAQKVTKEMDEFFSEDDDTMTTVTCIKSNHKVIALGCSSRQRSSIHLLSTSDYSLFARPLTDVFHDERGPVFSLGSRFIAYATNTAVLNSDPVMTSLTNKSIGYTGFGVLQGEKDVKGAAKDIAKEVVSGMKTLGEFGLNTLSNYFGNTPTSSSSSDKLMFTPSSPKRSNHSPIHHQSSSLSEGLYPSNNTIINSSKKMVPSGMIMIRDILKLPVTPTRNLSSSIVAHFRPHTHPVSCLTFNQAGTLLMSASKQGHTFHIFSILTYTTSASHLYSLSRGITDAQVEDCQFSVDSTWCAISTARGTTHVYAINPYGGKPEISGHVHGKVSNPFVPKPQKRSTASLKATTLSSVVRIKQRRKMPGYLQNTSQDDLTGKYGQGMANGNTPSSNGYGYYGPTPPHYVPMMMSRPSTTANPTQTSKEPRAKLTTMFVSATKSPYLVNNTMKHTAPASSSSPSDPSSSSSPHPSFSSIKQQASNMLSSFNLPYLPQQPQQHTNRSNNDTLMFGFDEEYDDAAKMINDEVGYQDMYSFHPDGFLTLHRCWVAKTVIKKRENGRVLEKLDLSLKEEDVAEWRVARNSEWDSVRFSLLDSPTTKPTSESSQEEEEPQKKAKKKNNSKNRPQMKEKEETSTLPVISPKRIWLSNAEIATYMPDEPPLWSHHQFSFQTYQSGQDVDSMLAAGILPSTDTIIMLKGMPEPVSSRIDRVSKTTTRIANDSVEENMEDALAELEDNISKAMQTSFSPSNNSVGNSPATNLKWLSSSANAIHVSSASSPHHHQRMYMDRNSSVSFEDAYLIHMGSGPSPEPSSQLGLTLVQNRHLEEEDDEIQTGVMQHSSLIQFDDDDDLSVQQMESNRMEAYSPDGDNEVEYPYESVFGELHTRMSNPDESDEDDQVPW</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NJ13</accession>
    <name>A0A1C7NJ13_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Hit family protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">hnt1</name>
        <name evidence="5" type="ORF">A0J61_03453</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000149">
        <property type="protein sequence ID" value="OBZ88496.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NJ13"/>
    <dbReference type="FunCoup" id="A0A1C7NJ13">
        <property type="interactions" value="215"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NJ13"/>
    <dbReference type="InParanoid" id="A0A1C7NJ13"/>
    <dbReference type="OrthoDB" id="672793at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009117">
        <property type="term" value="P:nucleotide metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01277">
        <property type="entry name" value="HINT_subgroup"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.428.10">
        <property type="entry name" value="HIT-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039384">
        <property type="entry name" value="HINT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019808">
        <property type="entry name" value="Histidine_triad_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001310">
        <property type="entry name" value="Histidine_triad_HIT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011146">
        <property type="entry name" value="HIT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036265">
        <property type="entry name" value="HIT-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46648:SF1">
        <property type="entry name" value="ADENOSINE 5'-MONOPHOSPHORAMIDASE HNT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46648">
        <property type="entry name" value="HIT FAMILY PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01230">
        <property type="entry name" value="HIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00332">
        <property type="entry name" value="HISTRIAD"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54197">
        <property type="entry name" value="HIT-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00892">
        <property type="entry name" value="HIT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51084">
        <property type="entry name" value="HIT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HIT" evidence="4">
        <location>
            <begin position="11"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Histidine triad motif" evidence="2 3">
        <location>
            <begin position="103"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="active site" description="Tele-AMP-histidine intermediate" evidence="1">
        <location>
            <position position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR601310-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR601310-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51084"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OBZ88496.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="143" mass="16080" checksum="B6C5F542232B0D84" modified="2016-11-30" version="1">MSHEHLKADCIFCKIIKGEIPSHKIAETEKSYSFLDINPLSEGHAKLTPARPDHAEFFHQVPDDVLADMLPLAKKVALAIGLGDGQYNLLQNNGRMAHQEVPHVHFHIIPKPNPQEGLKIGWDQQKVTQDNLKSLLGRIKEKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NJC5</accession>
    <name>A0A1C7NJC5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Protein BRE4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">BRE4_0</name>
        <name evidence="10" type="ORF">A0J61_02865</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000114">
        <property type="protein sequence ID" value="OBZ89088.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NJC5"/>
    <dbReference type="STRING" id="101091.A0A1C7NJC5"/>
    <dbReference type="InParanoid" id="A0A1C7NJC5"/>
    <dbReference type="OrthoDB" id="68611at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018823">
        <property type="entry name" value="ArAE_2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018820">
        <property type="entry name" value="BRE4-related_DUF2421"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052430">
        <property type="entry name" value="IVT-Associated"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049453">
        <property type="entry name" value="Memb_transporter_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47804">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47804:SF1">
        <property type="entry name" value="DUF2421 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10337">
        <property type="entry name" value="ArAE_2_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10334">
        <property type="entry name" value="BRE4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13515">
        <property type="entry name" value="FUSC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="195"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="242"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="274"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="302"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="340"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="820"/>
            <end position="839"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="880"/>
            <end position="906"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="957"/>
            <end position="974"/>
        </location>
    </feature>
    <feature type="domain" description="Putative ER transporter 6TM N-terminal" evidence="8">
        <location>
            <begin position="282"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="domain" description="Integral membrane bound transporter" evidence="9">
        <location>
            <begin position="842"/>
            <end position="968"/>
        </location>
    </feature>
    <feature type="domain" description="DUF2421" evidence="7">
        <location>
            <begin position="1052"/>
            <end position="1161"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="79"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="480"/>
            <end position="540"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="579"/>
            <end position="599"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="90"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="126"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="493"/>
            <end position="503"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="511"/>
            <end position="525"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF10334"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF10337"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF13515"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OBZ89088.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="1246" mass="142952" checksum="70E2E0998C469414" modified="2016-11-30" version="1">MDEDSPNRLPHNAATNLGASLSDAGLQELSTSPQSFFIERTQSLDNIMQERQHYLELGRSPSNFSEIEVILDDGTTQKRTVSLSTLPEYMQEEQTEEERSEDESSNDKTPLLKSHRDNNYQSISDTDSDSSDADGSDSDEPFFPIQQTASKRKHTAIEDDPQLSNWQSRLKSLFKSLYEASTLTPQQRLVLKCSFAYFLGSLFTFVPFLNALIGNNHTSSHLVATATVFFNPAKTLGGMVEAAAYGWGYVFFAVCICLGSMFTTDYFIDQNYFLVAYLFSLLFWLAGSTFIVAFLKAHWNKPPVATASSLCFIIIFIIVVREGSVNRGDFDTTRIEQITTAVATGTLITVACCVIFWPVSAAKKLKKDVDSTLNSYRVLLKLLVKTFLLDDDLPEFKANRTLQTAIQSHQASFTALQKSLKEAKLETFWNSEVRGRSVEYDAVIKSMQRLAQHVGGLRSSCGIQFEIMGSEATKQYKEMSRNKKQKKKRQQQFTPSPFKSASTGIFKANPGRSNNVSSKLSQSYVPPSALDGNDPYHPSWNVRAGYRRRRLQDEMRRQKTFMSRSDDMFDDFLKPNDLPSTSYTHPIPPSSIDEDTPESSDMPLVHFIQTIRPPLKSFAYTCKQTIYHLQHHFSTSSSSSWIPRIYGKSTKRTPSLSVLKANLEKAIALFESAQRQAVQKLYHSRVHAMQAKSNDKSEETHTVGLVLGEEVILVYFFVFNMVEFARELIVLVESVERLNNKKRTNVLSWIAASLKQLWNRKKNKGEHQKHLHHLNIVPFVPNERNMMNTLHTPTPKTKWRRFFIRIWRLFSLFKLQKIRYAFKAMVAAILLATPAFISYSQDWFRTYRMEWALITLMVVMTPTVGGTNLVAVYRIFSTALGCYVAMVFYMLFPGNMYVLVVLTWLFSIPNFYLILYNKHGKFGQFTLLAYNLVMLNKYNDRETNDVEVWVLANQRCLAILVGVIFGLIATAYVWPYEARVELRKGLSDFLLRLAWLYQKLVSIYIDYPTKNRIQANGQRELQQRTINIMEVGPNPSETQLLAFEAQRRLATQSFMDLELGLQRSLLDLQALLSQTPNEPRLKGPFPIDTYRTMLTSCQNIVDRFLSMRTVMLKDTWQNEVQHDFMIPVATERKEMVGNVLLYFYLLASALRLKTPMPPYFPPARKAWKTLLEQLFEMPVAKSEKMLEKNDVYMFYYAYVTLMEDIIRELDKLGENMTELFGSLVPPDQWNLLFDEEQQSVEGIHAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NJX6</accession>
    <name>A0A1C7NJX6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">RING-type E3 ubiquitin transferase</fullName>
            <ecNumber evidence="4">2.3.2.27</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="primary">dsc1</name>
        <name evidence="18" type="ORF">A0J61_02497</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18 19">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.</text>
            <dbReference type="EC" id="2.3.2.27"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Endomembrane system</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.27" evidence="4"/>
    <dbReference type="EMBL" id="LUGH01000095">
        <property type="protein sequence ID" value="OBZ89453.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NJX6"/>
    <dbReference type="FunCoup" id="A0A1C7NJX6">
        <property type="interactions" value="38"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NJX6"/>
    <dbReference type="InParanoid" id="A0A1C7NJX6"/>
    <dbReference type="OrthoDB" id="9984778at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043161">
        <property type="term" value="P:proteasome-mediated ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021319">
        <property type="entry name" value="DUF2921"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050731">
        <property type="entry name" value="HRD1_E3_ubiq-ligases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22763">
        <property type="entry name" value="RING ZINC FINGER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22763:SF162">
        <property type="entry name" value="TRANSMEMBRANE E3 UBIQUITIN-PROTEIN LIGASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11145">
        <property type="entry name" value="DUF2921"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13639">
        <property type="entry name" value="zf-RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="18" id="KW-0436">Ligase</keyword>
    <keyword evidence="13 16" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="6 16" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="12 16" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="10" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="11" id="KW-0862">Zinc</keyword>
    <keyword evidence="9 14" id="KW-0863">Zinc-finger</keyword>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="25"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="334"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="397"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="475"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="499"/>
            <end position="521"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="533"/>
            <end position="553"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="565"/>
            <end position="583"/>
        </location>
    </feature>
    <feature type="domain" description="RING-type" evidence="17">
        <location>
            <begin position="624"/>
            <end position="677"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="OBZ89453.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="683" mass="78593" checksum="920CEE56CABD5C4B" modified="2016-11-30" version="1">MDTENTANEQQRQQATTRRQQMNRSSSYILLLLFALLFFNFSEDSSMRTGKPTKADVLEELEQEKQTLNNMTFGTNITSPIPRIVQPQLDDLWSIRGPSTSHYYHNISGIFRGDWVNKNISIPDSVNKTQLEEARSQFQFDDPGSFKFNVKSVSTVEQDIHYVEGYIRLRDAEKSSYGALLLAGGLHFLSNGSLYLMVVPDGHTIPLKDMLNMLPSNHSFIQSRRVLNEQIDKRVEEINEASYWEWQASDEDHSDEMPFQCQFQLFAQLHPVPANIRMSELLEYERELEHPQGISTIRPPPFLMSTELYSPNCHLLLSSRENKGIKIEHYYNKAITYAGIASVIAVIQIFSLIHQMEYTPTPSSVSNVSYWTIAMQAIMDGYLCLLHLTTGVVVENVFIPFATAAFFTFVLVSIFGMRYLLVVWRIQRPESVRTDPSPQQQQQQAPDTQSLLPVANVRRPNPNEDANPQREITFLYYRLYAVLLLGLFLFYQSVTRSAFVQNIIIGSLGLLFFSFWIPQIARNVTRGCRHPLSYRYIIVMSITRLSVPLYFYGCPENLIGHDTTPWVFALVGYVGLQVLILFLQDSFGPRFFIPSKYMPQTYDYHPILSHEDEETDTSQPPKDCAICMLPIDVNHQHNSGLNVLSRTQYMVTPCHHMFHTDCLEKWMRIKLECPVCRAYLPAC</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NK44</accession>
    <name>A0A1C7NK44_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">thioredoxin-dependent peroxiredoxin</fullName>
            <ecNumber evidence="2">1.11.1.24</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">PRDX1</name>
        <name evidence="12" type="ORF">A0J61_02530</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>a hydroperoxide + [thioredoxin]-dithiol = an alcohol + [thioredoxin]-disulfide + H2O</text>
            <dbReference type="Rhea" id="RHEA:62620"/>
            <dbReference type="Rhea" id="RHEA-COMP:10698"/>
            <dbReference type="Rhea" id="RHEA-COMP:10700"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:30879"/>
            <dbReference type="ChEBI" id="CHEBI:35924"/>
            <dbReference type="ChEBI" id="CHEBI:50058"/>
            <dbReference type="EC" id="1.11.1.24"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.11.1.24" evidence="2"/>
    <dbReference type="EMBL" id="LUGH01000096">
        <property type="protein sequence ID" value="OBZ89425.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NK44"/>
    <dbReference type="FunCoup" id="A0A1C7NK44">
        <property type="interactions" value="531"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NK44"/>
    <dbReference type="InParanoid" id="A0A1C7NK44"/>
    <dbReference type="OrthoDB" id="185659at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008379">
        <property type="term" value="F:thioredoxin peroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045454">
        <property type="term" value="P:cell redox homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033554">
        <property type="term" value="P:cellular response to stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042744">
        <property type="term" value="P:hydrogen peroxide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006979">
        <property type="term" value="P:response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd03015">
        <property type="entry name" value="PRX_Typ2cys"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.30.10:FF:000003">
        <property type="entry name" value="Peroxiredoxin 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000866">
        <property type="entry name" value="AhpC/TSA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050217">
        <property type="entry name" value="Peroxiredoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024706">
        <property type="entry name" value="Peroxiredoxin_AhpC-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019479">
        <property type="entry name" value="Peroxiredoxin_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10681:SF171">
        <property type="entry name" value="PEROXIREDOXIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10681">
        <property type="entry name" value="THIOREDOXIN PEROXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10417">
        <property type="entry name" value="1-cysPrx_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00578">
        <property type="entry name" value="AhpC-TSA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000239">
        <property type="entry name" value="AHPC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 9" id="KW-0049">Antioxidant</keyword>
    <keyword evidence="6" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5 9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3 9" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="7 9" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin" evidence="11">
        <location>
            <begin position="3"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="active site" description="Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity" evidence="10">
        <location>
            <position position="49"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009796"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00049091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRNR" id="PIRNR000239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR000239-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="OBZ89425.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="202" mass="22746" checksum="50E67535CFAD5779" modified="2016-11-30" version="1">MVAQVQRPAPNFSAPGVNGGEIVANITLSDFRGKYVVFFWYPMDFTFVCPTEIIAFNDRLEEFRKLDCEVIAASGDSEYTHRAWIKTPRDQGGLGPDTILPIVADKTRRIATDYGIYLDQQGVSLRGLFIIDKNGIIRHITINDLPVGRSVDETLRLVEAFQFTDMHGEVCPANWKKGDHTLAPDVEKSKPFFKKTASKHQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NK66</accession>
    <name>A0A1C7NK66_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Protein FAM50</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_02443</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000092">
        <property type="protein sequence ID" value="OBZ89517.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NK66"/>
    <dbReference type="FunCoup" id="A0A1C7NK66">
        <property type="interactions" value="390"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NK66"/>
    <dbReference type="InParanoid" id="A0A1C7NK66"/>
    <dbReference type="OrthoDB" id="1562195at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000785">
        <property type="term" value="C:chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006325">
        <property type="term" value="P:chromatin organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048337">
        <property type="entry name" value="FAM50A/XAP5_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007005">
        <property type="entry name" value="XAP5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12722:SF0">
        <property type="entry name" value="PROTEIN FAM50A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12722">
        <property type="entry name" value="XAP-5 PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04921">
        <property type="entry name" value="XAP5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAM50A/XAP5 C-terminal" evidence="2">
        <location>
            <begin position="174"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="77"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="114"/>
            <end position="152"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04921"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ89517.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="313" mass="37240" checksum="9AFCBBD8ADC20BB5" modified="2016-11-30" version="1">MDSKGEGLRQSMLEKQRQKIYEESEKERQRNAKMSEVRVGSDKFVKTKTDIETQLKTSTIGLTELKDYRKIRENLEEQQKREAAKTAPLSDEKKKKKKKKQVLKLSFADEEEKELDEEEEEIEQKPAAKKRRMLKDPTIDTSFLPDREREEKERIEREELRKEWLRKQEEVKNEKIDITYSYWDGSGHRKVVTCKKGDSIQQFLDACRQQFPQLRGVNTDNLLYVKEDLIIPHHFTFYDFIINKARGKSGPLFNFDVHEDIRFVNDATIEKDESHAGKVVERAWYERNKHIFPASRWEIFDPAKSYGKYKIKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NK86</accession>
    <name>A0A1C7NK86_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Calponin-homology (CH) domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_02745</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000107">
        <property type="protein sequence ID" value="OBZ89219.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NK86"/>
    <dbReference type="STRING" id="101091.A0A1C7NK86"/>
    <dbReference type="InParanoid" id="A0A1C7NK86"/>
    <dbReference type="OrthoDB" id="2534759at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00014">
        <property type="entry name" value="CH_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.418.10">
        <property type="entry name" value="Calponin-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036872">
        <property type="entry name" value="CH_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38702">
        <property type="entry name" value="CALPONIN-HOMOLOGY (CH) DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38702:SF1">
        <property type="entry name" value="CALPONIN-HOMOLOGY (CH) DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47576">
        <property type="entry name" value="Calponin-homology domain, CH-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="115"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="227"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="115"/>
            <end position="124"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ89219.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="492" mass="55724" checksum="C692A08594C7CCAD" modified="2016-11-30" version="1">MNHPLDTDPIPTATQSTDSLPPIPDDDLSSFPIRRVSSPIPHNPDAIVRAQSPFGKRYLKPINGIQTKGFARSAQRRSSVVTLGSIERLQNFYAKKDLQVNKIGTLGFRNTILAEEPDDEDDDQLPTPQAPPPTWTELDVETDLDVLLSYCFEDIQSTLTAWSMVTGPHRASISSSSNSYLHSPLNETDESTHGSFQILPLLQSVTKMLGSVKNYTVNRHDLSDAALSKLRHASLDLLESMKELENEYRMHEEEDDHHGENSGYIYRSSDFSLLEKERLAIHNYLNVIQQYAFNPPHHIGSPPAMFTPEIQALMGKTQILSLTEEELHGQLEVMPTSVKQTVPVWLERGSFVDNPMNRYHALIIDNLDGSAEPSEVPDPDEDEDAFLQFLADGIIFCNVYNSLVKRSRRPFGLINKIHTDSRRTYRAIENLRFFSAACKFRFELVFDQFDPSEIARKTDKGLNMVKKVLTAFCECAINEFRQQLDSIQKQSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NKU5</accession>
    <name>A0A1C7NKU5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Vesicle-associated membrane protein-associated protein C16G5.05c</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">A0J61_02270</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass type IV membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the VAMP-associated protein (VAP) (TC 9.B.17) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000083">
        <property type="protein sequence ID" value="OBZ89685.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NKU5"/>
    <dbReference type="FunCoup" id="A0A1C7NKU5">
        <property type="interactions" value="156"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NKU5"/>
    <dbReference type="InParanoid" id="A0A1C7NKU5"/>
    <dbReference type="OrthoDB" id="264603at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033149">
        <property type="term" value="F:FFAT motif binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090158">
        <property type="term" value="P:endoplasmic reticulum membrane organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061817">
        <property type="term" value="P:endoplasmic reticulum-plasma membrane tethering"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000535">
        <property type="entry name" value="MSP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008962">
        <property type="entry name" value="PapD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016763">
        <property type="entry name" value="VAP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10809:SF6">
        <property type="entry name" value="AT11025P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10809">
        <property type="entry name" value="VESICLE-ASSOCIATED MEMBRANE PROTEIN-ASSOCIATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00635">
        <property type="entry name" value="Motile_Sperm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF019693">
        <property type="entry name" value="VAMP-associated"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49354">
        <property type="entry name" value="PapD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50202">
        <property type="entry name" value="MSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="328"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="domain" description="MSP" evidence="9">
        <location>
            <begin position="2"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="135"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="172"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="252"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="144"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="178"/>
            <end position="197"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50202"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OBZ89685.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="348" mass="39109" checksum="23A11E5063B9AA89" modified="2016-11-30" version="1">MSVVISPSEQLEFHRPFTRVSKESLHVKNPGSEPIVFKVKTTAPKQYCVRPNAGRIEANSEIEVQIILQPFREEPPEDYKCKDKFLVQTAPYPVVNDESQNDITTLWSYIEANERENMRQHKIKCVFLGPELRESDELQENESEQQTPQQQEQSPQEQMVEEISPIPEQAKNTEHVASSDTVLPPPLTSTTSTEPSSIQNDVPLKPASVNTTAATIAAPVAANTNSTTPTTTLYDTTRTPREVTQNNLTEATQTKKEEKDMTKEQLKEALDRVELLEKQLADIRKEEGLRARNQTGSSARKLASTVQPLDAVHQHLAALETPRSVEGYPPQVVMGIALLVFIFTYIFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NKX6</accession>
    <name>A0A1C7NKX6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">P-type Ca(2+) transporter</fullName>
            <ecNumber evidence="2">7.2.2.10</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="19" type="primary">pmc1_2</name>
        <name evidence="19" type="ORF">A0J61_02300</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="19 20" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19 20">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="15">
            <text>Ca(2+)(in) + ATP + H2O = Ca(2+)(out) + ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:18105"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="7.2.2.10"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="19">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="7.2.2.10" evidence="2"/>
    <dbReference type="EMBL" id="LUGH01000085">
        <property type="protein sequence ID" value="OBZ89648.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NKX6"/>
    <dbReference type="STRING" id="101091.A0A1C7NKX6"/>
    <dbReference type="InParanoid" id="A0A1C7NKX6"/>
    <dbReference type="OrthoDB" id="3352408at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005388">
        <property type="term" value="F:P-type calcium transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006874">
        <property type="term" value="P:intracellular calcium ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1110.10:FF:000039">
        <property type="entry name" value="Calcium-transporting ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, transmembrane domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006068">
        <property type="entry name" value="ATPase_P-typ_cation-transptr_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023298">
        <property type="entry name" value="ATPase_P-typ_TM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24093:SF369">
        <property type="entry name" value="CALCIUM-TRANSPORTING ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24093">
        <property type="entry name" value="CATION TRANSPORTING ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00689">
        <property type="entry name" value="Cation_ATPase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81665">
        <property type="entry name" value="Calcium ATPase, transmembrane domain M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0106">Calcium</keyword>
    <keyword evidence="4" id="KW-0109">Calcium transport</keyword>
    <keyword evidence="13" id="KW-0406">Ion transport</keyword>
    <keyword evidence="10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="14 17" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-1278">Translocase</keyword>
    <keyword evidence="5 17" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="12 17" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="54"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="77"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="120"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="194"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="226"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="domain" description="Cation-transporting P-type ATPase C-terminal" evidence="18">
        <location>
            <begin position="76"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="287"/>
            <end position="318"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022568"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00048694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="Pfam" id="PF00689"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="OBZ89648.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="318" mass="35294" checksum="B60FF0F4684BD46D" modified="2016-11-30" version="1">MADVGFSMGIAGTEVAKEASSIILMDDNFSSIVKAIMWGRCVNDAVKKFLEFQLTVNITAVILTFISAVASTEQKSVLTAVQLLWVNLIMDTFAALALATDPPTEELLLRRPEARTAPLITFKMWKMIIGQAAFQITVTLIILYTDVIHLPKDSAPLQTVVFNTFVFCQIFNEVNCRRIDSRINIFSNILANKFFIAIFFICVVGQVLIVQFGGPAFQVVPLDATQWAIAIVIGFVSLPIGVVIRLIPDDIFGFLFFSAAAREKYLGGHQNTVPSVYVAGNERMPWNPNERTNTMHSRSSKHNNDFRSYASGSIRSLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NKY1</accession>
    <name>A0A1C7NKY1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Plasma membrane iron permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">fip1</name>
        <name evidence="8" type="ORF">A0J61_03987</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the oxidase-dependent Fe transporter (OFeT) (TC 9.A.10.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000185">
        <property type="protein sequence ID" value="OBZ87964.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NKY1"/>
    <dbReference type="FunCoup" id="A0A1C7NKY1">
        <property type="interactions" value="58"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NKY1"/>
    <dbReference type="InParanoid" id="A0A1C7NKY1"/>
    <dbReference type="OrthoDB" id="4364at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033573">
        <property type="term" value="C:high-affinity iron permease complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061840">
        <property type="term" value="F:high-affinity ferrous iron transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033215">
        <property type="term" value="P:reductive iron assimilation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004923">
        <property type="entry name" value="FTR1/Fip1/EfeU"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31632">
        <property type="entry name" value="IRON TRANSPORTER FTH1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31632:SF2">
        <property type="entry name" value="PLASMA MEMBRANE IRON PERMEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03239">
        <property type="entry name" value="FTR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0406">Ion transport</keyword>
    <keyword evidence="3" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0410">Iron transport</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="6"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="50"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="86"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="141"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="174"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="200"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="288"/>
            <end position="307"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008333"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OBZ87964.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="368" mass="41374" checksum="C165FDD3BDCDA030" modified="2016-11-30" version="1">MSQDLFNVPIFFILFRETTEAAIIVSVLLSFLRKMFHTESPVYKRLRNQVWIGSIVGLFICICIGAAFIAVYYTVLNDLWGNSEDIWEGVFSLVATVMITVMGLAMLKTERMQEKWKVKLAKAIQKDSKEKSSFKEKLQKYAFFFLPFITVLREGLEAVVFIGGVSLGIPGKSIPIAAIMGIVCGCLVGLLIYRGGKLIHLRWFFVFSTVILYLVAAGLMSKGVGFLEQNSWNQVIGGEAADVISYRVSTSIWHVSWGDPELNVDTNGGWQIFNAILGWNNTATYGTIISYCLYWVFVICYLAFSFYKEKREAIRKAEAGEWDNGDQALDDARQYIDETGEIRQNLDSVESGKVDVSEKIDNSAPLKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NL34</accession>
    <name>A0A1C7NL34_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_02403</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the PHAF1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000090">
        <property type="protein sequence ID" value="OBZ89539.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NL34"/>
    <dbReference type="InParanoid" id="A0A1C7NL34"/>
    <dbReference type="OrthoDB" id="411211at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005802">
        <property type="term" value="C:trans-Golgi network"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043001">
        <property type="term" value="P:Golgi to plasma membrane protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005373">
        <property type="entry name" value="PHAF1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039156">
        <property type="entry name" value="PHAF1/BROMI"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13465:SF2">
        <property type="entry name" value="PHAGOSOME ASSEMBLY FACTOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13465">
        <property type="entry name" value="UPF0183 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03676">
        <property type="entry name" value="PHAF1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00024339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ89539.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="489" mass="54924" checksum="3B0736C904E06A6E" modified="2016-11-30" version="1">MTSAINEPSPKQPTRSKRIELVVVPGRSLGPFRLGSSLWDTLQLLLDKPNFFPSVELKYSQEHPLEHDFIISLSANGLHLRYDASLQRLKSVECYDPSKVKLVYQNSDVSSSRTIPTFLLIYKSFGPTYPGEFDAKSSIYTLKYPGLAFTFPIPTRHQNLYTSSTDLPLEFPDGTTPIASKVILYSNSHLWQQATVPSLPKVIAELNSSNTTKYGKLGKREVERVIARPTQGVTLLFPTYSHAADIPDNTKKNNTPPNPTPSANPIIHNSVSIKLNTTAAQDILADLGKPTRVFYKEEDKMKIHSVMTHHDIAVNKQHPIESKSNDTLINATDEKDKDPSVIQPTDYFFNYFHLGMDILIDGGLHVCKKIVLHGNIPGHYDFQRYKRCPFQMIFPPDSSKKQDASLLVDVEDESENTITADMKINTMQERIPWESSNTIKQNTAEQKPVILTRGSSEQNPFGSTYLTGYDEGVVMEVMKNGHVPTIVLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NLM5</accession>
    <name>A0A1C7NLM5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 5</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">ndufaf5</name>
        <name evidence="4" type="ORF">A0J61_02189</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000079">
        <property type="protein sequence ID" value="OBZ89759.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NLM5"/>
    <dbReference type="STRING" id="101091.A0A1C7NLM5"/>
    <dbReference type="InParanoid" id="A0A1C7NLM5"/>
    <dbReference type="OrthoDB" id="16816at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008757">
        <property type="term" value="F:S-adenosylmethionine-dependent methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032981">
        <property type="term" value="P:mitochondrial respiratory chain complex I assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050602">
        <property type="entry name" value="Malonyl-ACP_OMT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13090">
        <property type="entry name" value="ARGININE-HYDROXYLASE NDUFAF5, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13090:SF1">
        <property type="entry name" value="ARGININE-HYDROXYLASE NDUFAF5, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13489">
        <property type="entry name" value="Methyltransf_23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="4" id="KW-0830">Ubiquinone</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="301"/>
            <end position="325"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OBZ89759.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="325" mass="36180" checksum="A3B86DBB01E4BE24" modified="2016-11-30" version="1">MLSRSILQRIAVGSKRFYASATSTPQPFQVFDRHVKLLQKDRAASDVEQSRTVDYLKDEIAARVADRLLDINRDFDTVVDLGSGCGHIVKHATKNMMKKLIMCDMSEKALLRDKDIPYEVQVERKVVDEEYLPFEENSLDAVVSSLSLNWVNDLPGSLIQIKNSLKPDGVFIGAMFGGDTLFELRTSLQLAEVEREAGVSPRVSPMADSSDMSRLLTRAGFVLTTVDVDEIQVNYPSAFELMEDLKAMGENNAVLTRRPFLKRDTLMSAAAIYKELHGHPDGTIPATFSIIYLIGWKPSPETPLPKKRGSANASLKDILEDGESK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NLY0</accession>
    <name>A0A1C7NLY0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_02494</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000095">
        <property type="protein sequence ID" value="OBZ89456.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NLY0"/>
    <dbReference type="STRING" id="101091.A0A1C7NLY0"/>
    <dbReference type="InParanoid" id="A0A1C7NLY0"/>
    <dbReference type="OrthoDB" id="185373at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ89456.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="392" mass="45222" checksum="ACCD96B80CA8F7C5" modified="2016-11-30" version="1">MTHNILRTSSVNTCSKGALKTTRLFSTKKTGWFQRFLSPAEEKKLYLGITSSFREKLVEQSNKSTQTYSHIIEHALLTSPLKPTTGMLSITRIEQIKLDLDLAGKQKDLHRLQQLQLELDNANLTAIAVYNRLIRAYLWCDELALAENVLSNLEARELVPTVRTFTYLIQAHLKRHQIDQAKALVKKMDHLSLLKLRTSFDCAIMLKFYQSCGDTHAIDYVWRDLMTHATLVKPGLGLFTQYMEYLLDRQYDVKSVDKTVHQLLTHLQQDTSSITEHQYAVWIKSVNYLASKDQSAFTATAEQLLFFLMKRLPAKISWETINSSIDYILQSYLSEQQDLKMLAFYYKLRKLNIPDESFQKATLQSIETVLQRVETQSGQKDTMAKLEHLCLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NM66</accession>
    <name>A0A1C7NM66_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_01784</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000061">
        <property type="protein sequence ID" value="OBZ90165.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NM66"/>
    <dbReference type="InParanoid" id="A0A1C7NM66"/>
    <dbReference type="OrthoDB" id="5578001at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="176"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="319"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="182"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="340"/>
            <end position="351"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ90165.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="351" mass="40586" checksum="902F7887D90ED215" modified="2016-11-30" version="1">MEAIDDYANENIARSLAYTVLDQRQHCHYAKLLPISSQLLRQRVQILGPPSTEDSEEWDRLIQWQEDHCPDMIKALSDLDRIYQAPVYYRRLDIDTLHAMIEFAEKDAHHYVVILTLEEEGEGELSDLKYYNTKELTDEEWRDVFENWSRTIEDAERIFLTKVTRKRVFTPDSAKGVKEAPDDYWGDWSSEEETDQRETKGKNQVFSVDQDDSDEEAYYTRWSQDPGTLTPGPEQDTKNGRILHDINQQEIAEEYDQSYNPLFTVPSVPNLMDTHTAALSELTQMLQNTIPQNSRTANRPFVNPMTQINPLPKAVSRLRSSTDNLPSLLPGTYPESGQHSPKEEVVDGKML</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NMH4</accession>
    <name>A0A1C7NMH4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Glutamate carboxypeptidase 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">Folh1_1</name>
        <name evidence="4" type="ORF">A0J61_02299</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase M28 family. M28B subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000084">
        <property type="protein sequence ID" value="OBZ89666.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NMH4"/>
    <dbReference type="FunCoup" id="A0A1C7NMH4">
        <property type="interactions" value="48"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NMH4"/>
    <dbReference type="InParanoid" id="A0A1C7NMH4"/>
    <dbReference type="OrthoDB" id="5841748at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004180">
        <property type="term" value="F:carboxypeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.630.10:FF:000101">
        <property type="entry name" value="N-acetylated alpha-linked acidic dipeptidase like 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.930.40">
        <property type="entry name" value="Transferrin receptor-like, dimerisation domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.10">
        <property type="entry name" value="Zn peptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046450">
        <property type="entry name" value="PA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007484">
        <property type="entry name" value="Peptidase_M28"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039373">
        <property type="entry name" value="Peptidase_M28B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007365">
        <property type="entry name" value="TFR-like_dimer_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036757">
        <property type="entry name" value="TFR-like_dimer_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10404">
        <property type="entry name" value="N-ACETYLATED-ALPHA-LINKED ACIDIC DIPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10404:SF46">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04389">
        <property type="entry name" value="Peptidase_M28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04253">
        <property type="entry name" value="TFR_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52025">
        <property type="entry name" value="PA domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47672">
        <property type="entry name" value="Transferrin receptor-like dimerisation domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53187">
        <property type="entry name" value="Zn-dependent exopeptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0121">Carboxypeptidase</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0645">Protease</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase M28" evidence="3">
        <location>
            <begin position="293"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="domain" description="Transferrin receptor-like dimerisation" evidence="2">
        <location>
            <begin position="550"/>
            <end position="671"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005634"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04253"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF04389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OBZ89666.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="674" mass="76266" checksum="454478F5F5A16E88" modified="2016-11-30" version="1">MCLLFVYRFARVSSDISSSELMELLQSIPSIQSIEHYQVHYASQTRLAGSKSDKLLAEWTKDTWIDFGITDTQIKTYYPTLNRPVQRRVALFDKEELIYEAELQVLDAYGRALPAFHAYSADGNVTAPIVYVDYGRRGDFQYLAIRDIELKGAIALMRAGGDITHSMKIKMAQEFECVGALVFSGPDDEDALRSSFDLAKHHSAQFVSLHAGDPFTPGTSAKEDATHIPIQEANSLPKIPSLPISFKDAQFLLNYTHGYGIQKPGGFRYFSGPSENKVNLVNINKYQVKPIWNVIGRIQGEIEPHQSVILGSHRDGWTNDAVNHSSGSAVLTELVRTLGILLKKGWKPRRTIIIASWDAGEYGSIGSVEWVEDQKEWLRNEAVAYLNVDYAVSGKDFNAQASPLLDRLLRQAAEQTPYPHSNQSVYDAWKNRQRHNAPFYLTSLRQGTHQKSRLVSIPNTDSDHLAFFHHLGIASLSIGFQGNQYSMNQDIDWIRDLDNLVFDYHRSLTILWSIMLTRLSNDPILPLYPHDYALQIESAVHTFSAYKGCLDLPRISSAVSSFKSMSDNFQTNMLKWANSSLLNKNYLHNLRKHIKTINERLIQLERTFIHVEGISPDRPWFGHVLYGPDLYTGSSVLFPGLSEAMEKDNATLALWAEERIVEAIHQAEKTLSRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NMY4</accession>
    <name>A0A1C7NMY4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Up-regulated during septation protein 1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">A0J61_01479</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000047">
        <property type="protein sequence ID" value="OBZ90473.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NMY4"/>
    <dbReference type="InParanoid" id="A0A1C7NMY4"/>
    <dbReference type="OrthoDB" id="5569911at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029191">
        <property type="entry name" value="Uds1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15456">
        <property type="entry name" value="Uds1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Up-regulated during septation protein 1" evidence="3">
        <location>
            <begin position="44"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="324"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="478"/>
            <end position="505"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="532"/>
            <end position="559"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF15456"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OBZ90473.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="579" mass="68294" checksum="A7987C400CF3AD92" modified="2016-11-30" version="1">MTDNIDRWSFTSELDSLWNMKPKAAYNKTDTENDTMFSSSNLLVELLISQAILDSSEFKALSFDNLEALKKELKVIHDSIHHTTKNLQLENRIKNISKSLENANLKSSRHSVLYLADQRQSNENKIKQMSEFLEGLKERQVEIKKGLLQHTAAVLSKGIQNMELTAAKKRRNQLDYSDMLLPLQNELDLIARKVNKICASKFNINLSSSTVEKLLQLEKRLQTNGTGNQMAALNHLGNPKSFLNESNTHKISHEKMQLIAIEQQKDSYYNKMVDLELLTTKLLSHVDQFSQRQKALQMECMLYKTESIELEIWHKTWERDCALNTDNHPPSSQSDEIAHHQQLQQQAEKYESEINQQNILIQRNTRRYQQLEVDIHRLSDQKVDLESTIHSKSRLLDEKDRRITQLHLQLQSQKQASQTSNRYDTQLREQEKKRLNESFQQREACWTSHTHKKEDQFDELLESFDRLTNMAMEFDTDRMRYDKRISQLNHNVSELEMELITHKIKRLGFNNQEPPTTQLLRKEFRQLVADIKEAHQIRMEQEAEEIRRLQLQLEELHNTNHNTAYKYQQHISTQTDYWN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NN98</accession>
    <name>A0A1C7NN98_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_03213</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000134">
        <property type="protein sequence ID" value="OBZ88734.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NN98"/>
    <dbReference type="InParanoid" id="A0A1C7NN98"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="43"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ88734.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="74" mass="8643" checksum="33C27DC02FC43D98" modified="2016-11-30" version="1">MIRGILITDKPYLSLKVAKGKSCSTVSFEFEQRAKIYASSYDLLLQMFFFAIILVLFTFPLHFIQHLTCYQLMI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NP01</accession>
    <name>A0A1C7NP01_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Sperm motility kinase 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">Smok3a</name>
        <name evidence="5" type="ORF">A0J61_02943</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. CHEK2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000119">
        <property type="protein sequence ID" value="OBZ88994.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NP01"/>
    <dbReference type="STRING" id="101091.A0A1C7NP01"/>
    <dbReference type="InParanoid" id="A0A1C7NP01"/>
    <dbReference type="OrthoDB" id="10252171at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004672">
        <property type="term" value="F:protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.200.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000253">
        <property type="entry name" value="FHA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008984">
        <property type="entry name" value="SMAD_FHA_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24347">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00498">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00240">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49879">
        <property type="entry name" value="SMAD/FHA domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50006">
        <property type="entry name" value="FHA_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="FHA" evidence="3">
        <location>
            <begin position="28"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="4">
        <location>
            <begin position="135"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="494"/>
            <end position="531"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005575"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OBZ88994.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="531" mass="61632" checksum="0345736F42AE3B63" modified="2016-11-30" version="1">MNLVGLLRGANDNNKDFLAGIYDSRDAMKLGRKIDNDVIIDWHFVSELHCEIHTSSNRDSTNVYLTDKSLNGTFFNGSLIGYNKSVILYSGSVISFASSHLNLLYIGIDDKNHSQDENFNVVLQKEPAEHSKEITVINKPIGSGAESTILLAYHSLKSRYEIVCKSLRKHTWKRWMNKVSTEVDFLKKARHPNVLSIIGSCGHPTIKTRECVFYPLYAGGSLYERIKRKQYLEEEEASFLFFQVLHGLKSKHHPLRQNDRTRAVIGDFGLARQNNGNLWADEQYGTWLNHAPEIVKQEQYDERIDVWSAGIVLYLMLSGDHPFLESSEFRERHIESLDKVRDRIAQMDPLMRRKRIQECSSETQYLILSLLEKDPKKRYTASEALKDAFFLNKTVTDQRSFFEDYQTYVKEDFEQEREIWFDEKDDEDQSNYKFDQGILHPDDDDEQVSNLIKYRSSRSLHPIFKAKYAIEVDDDRFEEISNLLLSEQNPKASFRNNKRSSLLSENDSDNDNNKPNHDEEDENEGFSVCAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NPL3</accession>
    <name>A0A1C7NPL3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Ricin B lectin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_01030</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000028">
        <property type="protein sequence ID" value="OBZ90930.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NPL3"/>
    <dbReference type="InParanoid" id="A0A1C7NPL3"/>
    <dbReference type="OrthoDB" id="40579at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005854">
        <property type="term" value="C:nascent polypeptide-associated complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd23454">
        <property type="entry name" value="beta-trefoil_Ricin_GllA-1"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.80.10.50">
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.240">
        <property type="entry name" value="Putative phosphatase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016641">
        <property type="entry name" value="EGD2/NACA0like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023198">
        <property type="entry name" value="PGP-like_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035992">
        <property type="entry name" value="Ricin_B-like_lectins"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000772">
        <property type="entry name" value="Ricin_B_lectin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21713">
        <property type="entry name" value="NASCENT POLYPEPTIDE ASSOCIATED COMPLEX ALPHA SUBUNIT-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00652">
        <property type="entry name" value="Ricin_B_lectin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00458">
        <property type="entry name" value="RICIN"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50370">
        <property type="entry name" value="Ricin B-like lectins"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50231">
        <property type="entry name" value="RICIN_B_LECTIN"/>
        <property type="match status" value="6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ricin B lectin" evidence="2">
        <location>
            <begin position="7"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="domain" description="Ricin B lectin" evidence="2">
        <location>
            <begin position="199"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="domain" description="Ricin B lectin" evidence="2">
        <location>
            <begin position="454"/>
            <end position="617"/>
        </location>
    </feature>
    <feature type="domain" description="Ricin B lectin" evidence="2">
        <location>
            <begin position="892"/>
            <end position="1028"/>
        </location>
    </feature>
    <feature type="domain" description="Ricin B lectin" evidence="2">
        <location>
            <begin position="1421"/>
            <end position="1568"/>
        </location>
    </feature>
    <feature type="domain" description="Ricin B lectin" evidence="2">
        <location>
            <begin position="1811"/>
            <end position="1946"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1262"/>
            <end position="1320"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1355"/>
            <end position="1376"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="2056"/>
            <end position="2099"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="2612"/>
            <end position="2682"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="3984"/>
            <end position="4044"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="5500"/>
            <end position="5520"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1262"/>
            <end position="1274"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1279"/>
            <end position="1290"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1291"/>
            <end position="1311"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="2090"/>
            <end position="2099"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="2626"/>
            <end position="2637"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="2662"/>
            <end position="2671"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="3987"/>
            <end position="4000"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="4012"/>
            <end position="4021"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="5501"/>
            <end position="5515"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00458"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ90930.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="5983" mass="668982" checksum="EB30DE910A66C4AE" modified="2016-11-30" version="1">[encoded data, 5983 characters]</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NQC7</accession>
    <name>A0A1C7NQC7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">GDP/GTP exchange factor Sec2 N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">A0J61_00646</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000015">
        <property type="protein sequence ID" value="OBZ91321.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NQC7"/>
    <dbReference type="STRING" id="101091.A0A1C7NQC7"/>
    <dbReference type="InParanoid" id="A0A1C7NQC7"/>
    <dbReference type="OrthoDB" id="2289269at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051286">
        <property type="term" value="C:cell tip"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070319">
        <property type="term" value="C:Golgi to plasma membrane transport vesicle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005085">
        <property type="term" value="F:guanyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006887">
        <property type="term" value="P:exocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.910">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040351">
        <property type="entry name" value="RAB3IL/RAB3IP/Sec2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009449">
        <property type="entry name" value="Sec2_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14430">
        <property type="entry name" value="RABIN3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14430:SF0">
        <property type="entry name" value="SEC2P DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06428">
        <property type="entry name" value="Sec2p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144284">
        <property type="entry name" value="Sec2 N-terminal region"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GDP/GTP exchange factor Sec2 N-terminal" evidence="3">
        <location>
            <begin position="44"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="86"/>
            <end position="135"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF06428"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OBZ91321.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="268" mass="30988" checksum="4B70704F37A8AB16" modified="2016-11-30" version="1">MQVPKPLPALLAPSVTTIDISTDSRYLSSSIACFDTLPYEIQSKALLDTSKSYHHATTQAQLTEIQELRGDLIKLNHKYIQQMERAQIAQQARLQTEAELEDLSIKLFEQANGMVSEEKRKRVDAEKRAIQLENTLTYVVQELMQLKEFRSRFEIRTIEDEVMLKHTKSSFIAPSGSAARKMPNRLDDLCMDNRPIASLEDFLTWRPTAPIESLHKLIFGNYLLKRKSNKFGFNRKYIKLTTSFSDLLKYRFDKEKNKKKCQYSTLAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NQR8</accession>
    <name>A0A1C7NQR8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_00497</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000011">
        <property type="protein sequence ID" value="OBZ91443.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NQR8"/>
    <dbReference type="InParanoid" id="A0A1C7NQR8"/>
    <dbReference type="OrthoDB" id="18110at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06174">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23524:SF1">
        <property type="entry name" value="MRH DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23524">
        <property type="entry name" value="TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_8G04850)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="56"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="94"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="125"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="182"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="225"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="351"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="381"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="417"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="445"/>
            <end position="464"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ91443.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="489" mass="52478" checksum="C552622D3B65EF2E" modified="2016-11-30" version="1">MNLNKENAFNEKAETGTLDESIPVFSGSSCSHTSTSPSRKFLWLIPLNSDVHPLQFLAFIISVFVSLSLIVYISGTQSQIITGVLSITTNTGDITGSLTLYGEIVALVAVIVWSMVSDIIERRGVMSISILIMGMAIVCYPHVNSLYPXMLILKLMFSIGSAGSTAMMMAMVMEITHGKGGLISGCVGLSSGLGAIMAALLFFMVPATLSVRYPGPNHGITYSHSAIGGTAMVVAILLYFSLPKDSYKRPKTNHFKAWLNKLYQGIKAAKEPRIALGYTSSFFARADEVIISNFISLWITQYYIDNGRCKAGETCLYSLASSSSLTGYAQLVALCSTGFFGPASEYIPKELAVLVAGVVGACGCLPFAFSPDPTTKLXLGFVILLSCGQYGMIISGMAMCTGDYINQEHNAAISATYSFIGAVGIIIISKIGGVLFDVWMKGAPFLLLGIGHCLIAAMAILVYIHRLYAAYKKKKSDNLQSSDIVNDRC</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NR20</accession>
    <name>A0A1C7NR20_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Aladin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">Aaas</name>
        <name evidence="2" type="ORF">A0J61_00365</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000008">
        <property type="protein sequence ID" value="OBZ91553.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NR20"/>
    <dbReference type="STRING" id="101091.A0A1C7NR20"/>
    <dbReference type="InParanoid" id="A0A1C7NR20"/>
    <dbReference type="OrthoDB" id="10251741at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005643">
        <property type="term" value="C:nuclear pore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006913">
        <property type="term" value="P:nucleocytoplasmic transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045139">
        <property type="entry name" value="Aladin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057403">
        <property type="entry name" value="Beta-prop_Aladin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14494:SF0">
        <property type="entry name" value="ALADIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14494">
        <property type="entry name" value="ALADIN/ADRACALIN/AAAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25460">
        <property type="entry name" value="Beta-prop_Aladin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82171">
        <property type="entry name" value="DPP6 N-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aladin seven-bladed propeller" evidence="1">
        <location>
            <begin position="123"/>
            <end position="476"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF25460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ91553.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="490" mass="55155" checksum="98F27F3ED50BDDD7" modified="2016-11-30" version="1">MNLATRTIDTRVGTIAEIDGKLIEVQENSSTPTQVLTEKITLYPSIVHLPLIDQPADYVYKPTSSSSPIEAYYQQIKSTLHHCYQEKFSQLETTAAYQQAKAIYDRMDTRFLKQPDPRAKEDNSASPVQSVVWHPNQDMLAVADKEENNVYIYYKQDHVWSCYVLKHDNMKDITVMEWKQRSAGTLAVGCKQGVCVWTVPKVKLLSTEPQLHPSATMTYLTYPGHHAISAIAWDPTLGSHALAVGSSNSNTLVIFDLLLQRTNALKRYGHGTLLLRWSPDGDWLYETGPSTVSRMWDTKTWEYKSIRNPSGLYVQAACWAPDNRCLIFSMFNKSDIHILFLGGKDINNLMDHQLASFPLADLTTETGEVIKTAGVIRDIAVDQRHGQRLAIAFEHSPLIALCMYNLSSPLSLTPQPMLFPIGYIQPTHTLVDPSTGHLLSVSRLTDNLPHQITFSRHGVHGAVLAILWKNGLITFVTHHYLTKESSKRIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NR36</accession>
    <name>A0A1C7NR36_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Protein OS-9 homolog</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">yos9</name>
        <name evidence="12" type="ORF">A0J61_00584</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
            <orientation evidence="1">Lumenal side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the OS-9 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000013">
        <property type="protein sequence ID" value="OBZ91389.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NR36"/>
    <dbReference type="FunCoup" id="A0A1C7NR36">
        <property type="interactions" value="125"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NR36"/>
    <dbReference type="InParanoid" id="A0A1C7NR36"/>
    <dbReference type="OrthoDB" id="448954at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005788">
        <property type="term" value="C:endoplasmic reticulum lumen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030968">
        <property type="term" value="P:endoplasmic reticulum unfolded protein response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030970">
        <property type="term" value="P:retrograde protein transport, ER to cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.130.10">
        <property type="entry name" value="Mannose-6-phosphate receptor binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009011">
        <property type="entry name" value="Man6P_isomerase_rcpt-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044865">
        <property type="entry name" value="MRH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045149">
        <property type="entry name" value="OS-9-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012913">
        <property type="entry name" value="OS9-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15414:SF0">
        <property type="entry name" value="ENDOPLASMIC RETICULUM LECTIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15414">
        <property type="entry name" value="OS-9-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07915">
        <property type="entry name" value="PRKCSH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50911">
        <property type="entry name" value="Mannose 6-phosphate receptor domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51914">
        <property type="entry name" value="MRH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="6" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="5" id="KW-0430">Lectin</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="10">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008889845" description="Protein OS-9 homolog" evidence="10">
        <location>
            <begin position="20"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="domain" description="MRH" evidence="11">
        <location>
            <begin position="117"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="286"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="384"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="78"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="295"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="398"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="410"/>
            <end position="423"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004367"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00018727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022734"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51914"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="OBZ91389.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="423" mass="49536" checksum="8BDFCB5B468BA639" modified="2016-11-30" version="1">MKTVLSLAFAFQLVALSLQLQYIQDDVLGFPRYKIVLTHEKVSPSALARRDVELSSKENQIVMTSSLGQPFSCSIPNVQIEEERLEREKKERAQKETEQDKQKTIQRGLELLEPLEASCIRFLTSSHQYWAYEYCHNQYVRQFHVERTNDGKVEKEQETDSYILGYHPNSKHIDSSYSDQTKALRAKKKVHTELRNVGDQRYLVQTWKDGSICDLTEKPRTVEVQYHCDVQGQDRVSSFVEVSTCNYQIIVSTSRLCEEMSLFRRHHTEPHQIKCRPIVSEELIEQEQQQDEELQEQKQKQEQQKEQQEEQQGQKEQSEITKDLPKKENEKDLLLNMIFDLKDQIGQLKEQLNNKNKQAEVAYFTMDEQGNIVPGIELSKLIGQGKDDSKATRQKKLPTKEQKAQEQHQNRQAYNQKYIALQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NRC7</accession>
    <name>A0A1C7NRC7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">NudC domain-containing protein 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">NUDCD1</name>
        <name evidence="8" type="ORF">A0J61_00286</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000006">
        <property type="protein sequence ID" value="OBZ91653.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NRC7"/>
    <dbReference type="STRING" id="101091.A0A1C7NRC7"/>
    <dbReference type="InParanoid" id="A0A1C7NRC7"/>
    <dbReference type="OrthoDB" id="428655at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="CDD" id="cd06467">
        <property type="entry name" value="p23_NUDC_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.790">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007052">
        <property type="entry name" value="CS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008978">
        <property type="entry name" value="HSP20-like_chaperone"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037895">
        <property type="entry name" value="NUDCD1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21664">
        <property type="entry name" value="CHRONIC MYELOGENOUS LEUKEMIA TUMOR ANTIGEN 66"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21664:SF1">
        <property type="entry name" value="NUDC DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04969">
        <property type="entry name" value="CS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49764">
        <property type="entry name" value="HSP20-like chaperones"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51203">
        <property type="entry name" value="CS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CS" evidence="7">
        <location>
            <begin position="301"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="421"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="421"/>
            <end position="430"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00018915"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OBZ91653.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="602" mass="67226" checksum="084F59A37CEE3F1B" modified="2016-11-30" version="1">MKMNSRFKPDTSKLNLKFDGYKLAPLPGHDGVQRVALAEGNIQLYKPSHDQRFGFRDLQARIRYSHLIYGYPLDQNRGSCFCIDYDFNVHMIVYDKLTKETKFALITQLIKPLVGLPGFTEPKSSVPLEPQMPSAIAVSKELLVATNGVGDIELIGFEEKDGNLLGTSLGAVAYTGTGTEGISPVPCVLLAARQIKSTIILVVYSRAASTPSDTMSIAAEFHIATLKLHLPTEHTKRLDDGSFVLELDTMHIQKGAEVPVYCAITPSGQQIILGSEVKYNTVHPVQEQDEPMEEAVDPPSPKQPSYQWTQDGADITLQFQLPANTPKSAIHCNFVVDHLSLIVKDTAISFPYRKLWGTVQPDESTWTIDKDGLLTLFMTKTDERTRWPQLFDQDDGVLETLSATALSNITQQLDRFTSEPDTNMSSSFVHPSQHPAATDMDEDVDDEGTPVVFSVYQNSSGRVVDEFHSGAYRYVSQSFWHPHLPSICLQMDVDGLVFSLTETEDGSIEIQHEDTVHAFAFVQASKRDARFIHIDPECHFASIVESSRNAYIYYHHQDKRLIEQQALVDLTQGSQVDIVGVQRIFDNTLMVLTESHVVILHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NRI3</accession>
    <name>A0A1C7NRI3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">BZIP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">A0J61_02093</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000075">
        <property type="protein sequence ID" value="OBZ89854.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NRI3"/>
    <dbReference type="STRING" id="101091.A0A1C7NRI3"/>
    <dbReference type="InParanoid" id="A0A1C7NRI3"/>
    <dbReference type="OrthoDB" id="2593073at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090575">
        <property type="term" value="C:RNA polymerase II transcription regulator complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001228">
        <property type="term" value="F:DNA-binding transcription activator activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000976">
        <property type="term" value="F:transcription cis-regulatory region binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd14688">
        <property type="entry name" value="bZIP_YAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.170">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050936">
        <property type="entry name" value="AP-1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004827">
        <property type="entry name" value="bZIP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046347">
        <property type="entry name" value="bZIP_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40621:SF6">
        <property type="entry name" value="AP-1-LIKE TRANSCRIPTION FACTOR YAP1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40621">
        <property type="entry name" value="TRANSCRIPTION FACTOR KAPC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00170">
        <property type="entry name" value="bZIP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57959">
        <property type="entry name" value="Leucine zipper domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00036">
        <property type="entry name" value="BZIP_BASIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BZIP" evidence="5">
        <location>
            <begin position="114"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="89"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="202"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="137"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="204"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="225"/>
            <end position="245"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS00036"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OBZ89854.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="323" mass="36781" checksum="666F79274F6375DD" modified="2016-11-30" version="1">MDINYKEDNNMYSNTMSQQTTFDHRQAVLSHKWNYPSSTMRDWSKITHMFSVTANQPFHYNVWTQNNNKLGHCSAYCCLSFPYSSPLPPHAPPPSPTCFSSPPNKARKMTTKSKRAEQNRAAQRAFRLRKERYVKDLERKAQLLDEWRVEIELLRQENQQLREVNQRLEQEQKQPMKKLTLSKMPPPIVTLVDPLQCKKRKLSSALSGAPNQENEPLQSPTAVLPPYSSSVSSPLSSSTSPISPSDQDNTAFLLTSSYTSPYTNEQAYLHTFPLAPCSSFEGSTGYPTLSMYDMFPGNKVYSQGDNGYPSSLNVSHDNYVCRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NS27</accession>
    <name>A0A1C7NS27_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_00007</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000001">
        <property type="protein sequence ID" value="OBZ91922.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NS27"/>
    <dbReference type="InParanoid" id="A0A1C7NS27"/>
    <dbReference type="OrthoDB" id="2276838at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="48"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="64"/>
            <end position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ91922.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="75" mass="8151" checksum="7F85B5C28D98B251" modified="2016-11-30" version="1">MDVGQLKNPFSKKSSESSSGSTGLFKIGDYDTQPASQNTNKQEEPSIVKQTAETVKNEAQSMVDKAKGRDDNVNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NTA8</accession>
    <name>A0A1C7NTA8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Type 1 phosphatases regulator</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">YPI1</name>
        <name evidence="4" type="ORF">A0J61_01215</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Regulator of type 1 phosphatases which maintains protein phosphatase activity under strict control.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the YPI1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000036">
        <property type="protein sequence ID" value="OBZ90734.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NTA8"/>
    <dbReference type="STRING" id="101091.A0A1C7NTA8"/>
    <dbReference type="InParanoid" id="A0A1C7NTA8"/>
    <dbReference type="OrthoDB" id="307488at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008157">
        <property type="term" value="F:protein phosphatase 1 binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004865">
        <property type="term" value="F:protein serine/threonine phosphatase inhibitor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011107">
        <property type="entry name" value="PPI_Ypi1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20835:SF0">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE PPP1R11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20835">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE PPP1R11-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07491">
        <property type="entry name" value="PPI_Ypi1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="88"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="18"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="101"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="121"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="147"/>
            <end position="162"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU367162"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OBZ90734.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="162" mass="18457" checksum="9BFAC7EA556A4FC1" modified="2016-11-30" version="1">MSSSPHPATSTRMREETPTTTHGSRTITLDETIANSANELSSDEEGEQVGVLRLTGDMESRRRRVIQWDDNVIDNEHMNKKKSKICCIYHKPRPVGESSDDSSSSSDDSSNSDSEDSHSGRCNHRHSHRKKKRNPRDVSPNAYERQPVYKDRIKPVNQPQRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7ML60</accession>
    <name>A0A1C7ML60_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_11864</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01002606">
        <property type="protein sequence ID" value="OBZ77179.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7ML60"/>
    <dbReference type="InParanoid" id="A0A1C7ML60"/>
    <dbReference type="OrthoDB" id="2296461at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="100"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="100"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="229"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ77179.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="229" mass="25534" checksum="35909E5712641D18" modified="2016-11-30" version="1" fragment="single">MVREKAVQHFIYTDEDVSGPVLVSDSASVVTQTTHRRWRNQPVQKFIGAFEIAAKNYIIEWMQKSPNPVSGKSVLKAKRTVPSGLYAKVEDMANLEKGEASARFSDDSSLPKEFQESATAGTPSDFLSALTMYSPMSAASPSADMPMLPEDVPEELETEETDDKNYAVCTVSFSLILRKNLNGPIKTIFNTKMNMLIRSASDFVADFQLLVFLTMLSFRNHTFVLDTNQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MTA6</accession>
    <name>A0A1C7MTA6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_11836</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01002565">
        <property type="protein sequence ID" value="OBZ80115.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MTA6"/>
    <dbReference type="STRING" id="101091.A0A1C7MTA6"/>
    <dbReference type="InParanoid" id="A0A1C7MTA6"/>
    <dbReference type="OrthoDB" id="2287260at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ80115.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="83" mass="9773" checksum="8FFA8F19AC866FC8" modified="2016-11-30" version="1" fragment="single">MQQSSSISSTTLEFDLVMEALIIKVRPSTALAYRTLLEHWKEFCDNNRHRFPVDPMYPYTVGPTEFVIAFFKEFVIAFFKEFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MTX4</accession>
    <name>A0A1C7MTX4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_11673</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01002323">
        <property type="protein sequence ID" value="OBZ80278.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="InParanoid" id="A0A1C7MTX4"/>
    <dbReference type="OrthoDB" id="2286663at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ80278.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="233" mass="26769" checksum="B729DC7882A2BD2B" modified="2016-11-30" version="1">MVDISSGRIEKVLPPRRKISVRGRPKNVKRQQIQYELTVEKEKGNARKEVKEEKKAERFVEKKIELLQNKKNRGELIVRKRKASIMMYGKEDFLFDKHFKAHKRSRGVISGSFESVLSSAITKIDITGYLDPKPEATVDSEQLLFLLKKMTELIKTKXNIFKFEKVIKKGMNKSDLAEWFYSSDCAQVTADAYGIPVCVYPSLENEHAAINHPLTFLPPELPKTKSKPIAIHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MUG0</accession>
    <name>A0A1C7MUG0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">H/ACA ribonucleoprotein complex subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">GAR1_1</name>
        <name evidence="10" type="ORF">A0J61_11832</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Required for ribosome biogenesis. Part of a complex which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Pseudouridine ("psi") residues may serve to stabilize the conformation of rRNAs.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Component of the small nucleolar ribonucleoprotein particles containing H/ACA-type snoRNAs (H/ACA snoRNPs).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 8">Nucleus</location>
            <location evidence="1 8">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7 8">Belongs to the GAR1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01002559">
        <property type="protein sequence ID" value="OBZ80119.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MUG0"/>
    <dbReference type="FunCoup" id="A0A1C7MUG0">
        <property type="interactions" value="427"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7MUG0"/>
    <dbReference type="InParanoid" id="A0A1C7MUG0"/>
    <dbReference type="OrthoDB" id="2187159at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031429">
        <property type="term" value="C:box H/ACA snoRNP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034513">
        <property type="term" value="F:box H/ACA snoRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000454">
        <property type="term" value="P:snoRNA guided rRNA pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.10.230:FF:000001">
        <property type="entry name" value="H/ACA ribonucleoprotein complex subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.230">
        <property type="entry name" value="Probable tRNA pseudouridine synthase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038664">
        <property type="entry name" value="Gar1/Naf1_Cbf5-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007504">
        <property type="entry name" value="H/ACA_rnp_Gar1/Naf1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23237:SF6">
        <property type="entry name" value="H_ACA RIBONUCLEOPROTEIN COMPLEX SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23237">
        <property type="entry name" value="NUCLEOLAR PROTEIN FAMILY A MEMBER 1 SNORNP PROTEIN GAR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04410">
        <property type="entry name" value="Gar1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="Translation proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 8 10" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 8" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="4 8" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3 8" id="KW-0698">rRNA processing</keyword>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="115"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="9">
        <location>
            <begin position="143"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="10">
        <location>
            <position position="197"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00038293"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU364004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OBZ80119.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="197" mass="20051" checksum="68D2AEDFE3769E51" modified="2016-11-30" version="1" fragment="single">MGFGQRGGFRGGRGGFNNNQGPPAEVVVAGTFVSACEGEMVCQLTNAKVPFFNAPIYLQDKTLIGKVDEILGPLNEVFFTVKMQDGQNASQFKKEDKVYIGLDKLLPMDRFIPKPKVAGKASKPTGLQGKVEKKTKAPAARGSRGGFASRGGSSRGGGGRGGFGGGRGGGGFESRGGGRGGFASRGGGRGGFGGGAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MVE1</accession>
    <name>A0A1C7MVE1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Peroxin-7</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">A0J61_11222</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001794">
        <property type="protein sequence ID" value="OBZ80728.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MVE1"/>
    <dbReference type="STRING" id="101091.A0A1C7MVE1"/>
    <dbReference type="InParanoid" id="A0A1C7MVE1"/>
    <dbReference type="OrthoDB" id="273771at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005782">
        <property type="term" value="C:peroxisomal matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005053">
        <property type="term" value="F:peroxisome matrix targeting signal-2 binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016558">
        <property type="term" value="P:protein import into peroxisome matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044536">
        <property type="entry name" value="PEX7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46027">
        <property type="entry name" value="PEROXISOMAL TARGETING SIGNAL 2 RECEPTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46027:SF1">
        <property type="entry name" value="PEROXISOMAL TARGETING SIGNAL 2 RECEPTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0653">Protein transport</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OBZ80728.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="64" mass="7256" checksum="E088C38460CC28D0" modified="2016-11-30" version="1" fragment="single">AAYDMSVRFWDTAAAPGQNLIHVHDAHTEFALGLDFNLYREGQVATCAWDEKLNVFVPPPLLRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MVF8</accession>
    <name>A0A1C7MVF8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF6570 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_11151</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001717">
        <property type="protein sequence ID" value="OBZ80800.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MVF8"/>
    <dbReference type="STRING" id="101091.A0A1C7MVF8"/>
    <dbReference type="InParanoid" id="A0A1C7MVF8"/>
    <dbReference type="OrthoDB" id="2290773at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046700">
        <property type="entry name" value="DUF6570"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20209">
        <property type="entry name" value="DUF6570"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF6570" evidence="1">
        <location>
            <begin position="65"/>
            <end position="189"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF20209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ80800.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="308" mass="34577" checksum="F181784BEFA9763F" modified="2016-11-30" version="1">MIKEGPTVVCVCCGGLWFPGQTKTVTKAFLLSREATEEFIERVFNVETTDQLEEFCDNCSLFVKKKKVPRLCLSNGLKLPEISEEIKRLNRIEERLVAARHVYQSIYTVFGLRGQYKSKGEIVNVPVSVDKTVSCIPRLPEDTNIIQVTLKRRLDQANNYMSGNVNIASVWAAAVVLKDTDAYKKHTVTIRDSLEIFNELSILTSEQNLMDELVEALADIDINDDDAMDEIANPGGAETLYSGIEFPTMPIEIYTEGIQITPAEDSRPMRLLLDKDVEYLAFSTLFGGAIMEPIYEEKPISYASIVKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MVX3</accession>
    <name>A0A1C7MVX3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">ATP-dependent DNA helicase</fullName>
            <ecNumber evidence="1">5.6.2.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_11042</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="5.6.2.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the helicase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.6.2.3" evidence="1"/>
    <dbReference type="EMBL" id="LUGH01001617">
        <property type="protein sequence ID" value="OBZ80908.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MVX3"/>
    <dbReference type="STRING" id="101091.A0A1C7MVX3"/>
    <dbReference type="InParanoid" id="A0A1C7MVX3"/>
    <dbReference type="OrthoDB" id="5860629at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043139">
        <property type="term" value="F:5'-3' DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000723">
        <property type="term" value="P:telomere maintenance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010285">
        <property type="entry name" value="DNA_helicase_pif1-like_DEAD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10492">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10492:SF57">
        <property type="entry name" value="ATP-DEPENDENT DNA HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05970">
        <property type="entry name" value="PIF1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0227">DNA damage</keyword>
    <keyword evidence="1" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="1" id="KW-0234">DNA repair</keyword>
    <keyword evidence="1" id="KW-0347">Helicase</keyword>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA helicase Pif1-like DEAD-box helicase" evidence="2">
        <location>
            <begin position="32"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="domain" description="DNA helicase Pif1-like DEAD-box helicase" evidence="2">
        <location>
            <begin position="69"/>
            <end position="153"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU363044"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF05970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ80908.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="219" mass="24335" checksum="6F7E495B27B9BBA0" modified="2016-11-30" version="1">MMNAGQKVAFDEIVDNISSNPKTAHFFLQGSAAVVCVASSGIASLLLPGGRTSHSRFKIPLNIFPESAVNPTLQDICSDFDSLFGGILVVLGGDFAQIGPVIKHGQRHHIVEASLAKSTEIWPRVKKLKLKENMRLASSNHVDRAFSQWIGNLSYNSMLNGKISLLQYIPQHHSLFTFVDSIYPKEILEQTLNPDFFQERAIIAPRNDMVDKINKYVLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MWH5</accession>
    <name>A0A1C7MWH5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_10716</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001337">
        <property type="protein sequence ID" value="OBZ81235.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MWH5"/>
    <dbReference type="InParanoid" id="A0A1C7MWH5"/>
    <dbReference type="OrthoDB" id="2266444at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="104"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="132"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ81235.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="545" mass="62261" checksum="51AF01D9A5DC8B7B" modified="2016-11-30" version="1">MKDFWTTEPCDWTITNYLFKLFAQDPALTRRSASNRLINDSTIIKNHVIAGTIAETMASTMSSFTQNSRGKKTFNAFFVNHATQMTEETLKYDVQKTRLKSAMAEQVANEEEKENARKRLMDGNDCEGGPSRRTKASRRKVCTVIDDNQTSEQDEDYDHNDSGDDKKDSIWEEWKQFLDDQENMNCFMQLSPERHKVIWCGKLVRRRSCLPPELYDKLNQEIPLVTMQDINPCLAEMSSAVFDAESNTEMQSCIELLNCVVLNDPVFIAEKKLIVDICRTLNDYIYDNCGLEVLQKSESCYRSYLFDKCLMATTKYLRNVNHDVTFFPGEIELNSMTTQLKQKGMNDGRYKYNADGTLIANNFSAIEILLTEVSSGYGSNEAGKISFDHYKAMFGMLAMIRTVAQLCEKASFSIFAKLKIHFLHAHGNSIRHWSMSTQAPGIYIMTKEQRVNVPISFSEKDIKILPFICFFKTLVIACEETLSVLKELRQEHKTILRSKGQRPQKLSSIINPTIIRLNEGKHTSIVAEHGPMSVPNSPNPYPVLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-06-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MXK2</accession>
    <name>A0A1C7MXK2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_10462</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001186">
        <property type="protein sequence ID" value="OBZ81491.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MXK2"/>
    <dbReference type="InParanoid" id="A0A1C7MXK2"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ81491.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="81" mass="9568" checksum="C173B01E7E02FB6E" modified="2016-11-30" version="1" fragment="single">MKDSDTIIELLDKEERMMTDQMIYNDNMVQPAIHNWNSNCYFSLYASTSDQRYVAYLSTSHMDKETLTYMEKANISIIDCH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MXW4</accession>
    <name>A0A1C7MXW4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">BLOC-1-related complex subunit 6 C-terminal helix domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_10289</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001104">
        <property type="protein sequence ID" value="OBZ81662.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MXW4"/>
    <dbReference type="STRING" id="101091.A0A1C7MXW4"/>
    <dbReference type="InParanoid" id="A0A1C7MXW4"/>
    <dbReference type="OrthoDB" id="21270at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046465">
        <property type="entry name" value="BORCS6_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10157">
        <property type="entry name" value="BORCS6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BLOC-1-related complex subunit 6 C-terminal helix" evidence="1">
        <location>
            <begin position="1"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF10157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ81662.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="104" mass="11844" checksum="F778B95BC4CF25F7" modified="2016-11-30" version="1" fragment="single">DLDSLESLQEKAKELSQRFVNQVEHIQQQMRQVNSTMEAGKLYTLSVRNLAEEIDSSFRKTTELITHCDELDKDLAQLQILSKQVKAVDKGLDRLQAALSAKRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-06-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MXX3</accession>
    <name>A0A1C7MXX3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_10271</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001097">
        <property type="protein sequence ID" value="OBZ81680.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MXX3"/>
    <dbReference type="InParanoid" id="A0A1C7MXX3"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ81680.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="204" mass="22892" checksum="25B581871AEFFC8A" modified="2016-11-30" version="1">MTTLFLREINYHDYPKQLSAYLYLALYTAKVLLIRHFRLKIDEQARIAAALEQYYNVPWTYPRPESPPWSPLPSPVIRPVEGKVDGDASLADDRIKLDETPASIRSVQQAQPESDDRMFLQSLCRMKRQCLSLYQSRYLTGVFDAKPKPTSVVAEVCIAPDDDGVFSAAFIREMAAALLEAGIAEDGGAFSNDFITDMKAALPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MXY2</accession>
    <name>A0A1C7MXY2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Survival factor 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">svf1</name>
        <name evidence="6" type="ORF">A0J61_10283</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SVF1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001102">
        <property type="protein sequence ID" value="OBZ81668.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MXY2"/>
    <dbReference type="FunCoup" id="A0A1C7MXY2">
        <property type="interactions" value="27"/>
    </dbReference>
    <dbReference type="InParanoid" id="A0A1C7MXY2"/>
    <dbReference type="OrthoDB" id="2590239at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006979">
        <property type="term" value="P:response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051385">
        <property type="entry name" value="Ceramide-binding_SVF1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033394">
        <property type="entry name" value="Svf1-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013931">
        <property type="entry name" value="Svf1-like_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47107:SF1">
        <property type="entry name" value="CERAMIDE-BINDING PROTEIN SVF1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47107">
        <property type="entry name" value="SVF1-LIKE PROTEIN YDR222W-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08622">
        <property type="entry name" value="Svf1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17187">
        <property type="entry name" value="Svf1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF159245">
        <property type="entry name" value="AttH-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Svf1-like N-terminal" evidence="4">
        <location>
            <begin position="56"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="domain" description="Svf1-like C-terminal" evidence="5">
        <location>
            <begin position="214"/>
            <end position="380"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF08622"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF17187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OBZ81668.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="382" mass="42778" checksum="C0E599D385F9C9CE" modified="2016-11-30" version="1">MSSWFSQITSTVSNVTGLGTNVETVQTVADTIKDGQAYTALDNKDLEWTLASGSSTENQVFYVTTKTGAFAFVQLIHSNIGLWNPTISFTCRFYDPETNTNVFKNINMSKFELSADKRSVKTDFISIQLDAEQKAYKINITHPELVVSLDFDRVDKGFKVGEGKTYLGGDKASAAGFVSHKFWPRANAKGTFIVNQKIHEVEGDGMFVHAIQGMQPQLIASNWNFVNFHSEKASIGMMQFQTTKQYGSVNINQGSLVLNGELICVSIDNSVELLDMVKDNETDYDIPQKVKLTWKGKTIKKQENEEPKDVVIEMVVDVKNLIDKIDILAEIPYVIRKLVQSLIVKPYIYQWLDKATAEITVGDEKVSTEGHCFQELVFVSGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MZ57</accession>
    <name>A0A1C7MZ57_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="12">S-adenosylmethionine mitochondrial carrier protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">slc25a26_1</name>
        <name evidence="13" type="synonym">slc25a26_0</name>
        <name evidence="13" type="ORF">A0J61_07475</name>
        <name evidence="12" type="ORF">A0J61_09898</name>
    </gene>
    <organism evidence="12 14">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="12 14" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 14">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000967">
        <property type="protein sequence ID" value="OBZ82051.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="LUGH01000505">
        <property type="protein sequence ID" value="OBZ84478.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MZ57"/>
    <dbReference type="FunCoup" id="A0A1C7MZ57">
        <property type="interactions" value="324"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7MZ57"/>
    <dbReference type="InParanoid" id="A0A1C7MZ57"/>
    <dbReference type="OrthoDB" id="276989at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.50.40.10:FF:000018">
        <property type="entry name" value="S-adenosylmethionine mitochondrial carrier protein-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002067">
        <property type="entry name" value="MCP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45667">
        <property type="entry name" value="S-ADENOSYLMETHIONINE MITOCHONDRIAL CARRIER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00926">
        <property type="entry name" value="MITOCARRIER"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 10 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 11" id="KW-0813">Transport</keyword>
    <feature type="repeat" description="Solcar" evidence="10">
        <location>
            <begin position="8"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="10">
        <location>
            <begin position="91"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="10">
        <location>
            <begin position="182"/>
            <end position="271"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU000488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="OBZ82051.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="OBZ84478.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="282" mass="30515" checksum="64ED069A7AB60284" modified="2016-11-30" version="1">MSSSNQQSNLKQALVAGACAGTAVDTALFPLDTIKTRLQSQHGFIASGGFRGIYSGLLTAVIGSAPGASLFFVTYEATKRLLGATVDNPQYAPLIHMAAASCGETVACTVRVPTEVIKQRMQTKQFTKTSAAVSHVLRTEGILGMYRGFLSTVAREIPFTCIQFPLYEYFKRSYATMQGRPTEPYEAALMGSLAGAIAAGATTPLDVCKTRIMLSTKHQTTKHYDGIISTMKRIAAEEGPRALFSGIGPRMMWISIGGSIFLGVYEKALKTFVQLRVLDERY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MZU1</accession>
    <name>A0A1C7MZU1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Chitin deacetylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">CDA_1</name>
        <name evidence="2" type="ORF">A0J61_10032</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001007">
        <property type="protein sequence ID" value="OBZ81919.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MZU1"/>
    <dbReference type="STRING" id="101091.A0A1C7MZU1"/>
    <dbReference type="InParanoid" id="A0A1C7MZU1"/>
    <dbReference type="OrthoDB" id="407355at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004099">
        <property type="term" value="F:chitin deacetylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009272">
        <property type="term" value="P:fungal-type cell wall biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.370">
        <property type="entry name" value="Glycoside hydrolase/deacetylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011330">
        <property type="entry name" value="Glyco_hydro/deAcase_b/a-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002509">
        <property type="entry name" value="NODB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050248">
        <property type="entry name" value="Polysacc_deacetylase_ArnD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10587:SF98">
        <property type="entry name" value="CHITIN DEACETYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10587">
        <property type="entry name" value="GLYCOSYL TRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01522">
        <property type="entry name" value="Polysacc_deac_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88713">
        <property type="entry name" value="Glycoside hydrolase/deacetylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51677">
        <property type="entry name" value="NODB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NodB homology" evidence="1">
        <location>
            <begin position="1"/>
            <end position="132"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ81919.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="204" mass="22213" checksum="19BB4889D1D0C6C9" modified="2016-11-30" version="1">MTTLTNEEVLAELYYTQKAIKHVTGLTPKYWRPAQGDLDDRVRWIATQLNLTAIIWNLDTDDWAAGTVAGVTKETVNQNYENFIQMGSNGTFSQSGNIVLSHEINNMTMDFFMNHFPQIKKSYKHVLDVATCMNITNPYVESSVTFPTFEQAVTGVSGSSGNSSSSNNVTANASKATATSGASPAQILNGPLFIAALFGLFVLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MZY2</accession>
    <name>A0A1C7MZY2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_09597</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000887">
        <property type="protein sequence ID" value="OBZ82352.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MZY2"/>
    <dbReference type="InParanoid" id="A0A1C7MZY2"/>
    <dbReference type="OrthoDB" id="20865at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018482">
        <property type="entry name" value="Znf-C4H2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31058">
        <property type="entry name" value="ZINC FINGER C4H2 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31058:SF2">
        <property type="entry name" value="ZINC FINGER C4H2 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10146">
        <property type="entry name" value="zf-C4H2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="45"/>
            <end position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ82352.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="167" mass="19709" checksum="65B2A96D44F3518E" modified="2016-11-30" version="1">MNNNHSVDADLGTIKSQTNTLEKLREKTQALLDCKATYMSKSEILEQKKNFLEEASSEKQRLQREKRLLREMLQSINQDLNSIVDIEIALNRESEDLEKTLDKLKKEQYEPLHDQVNEIRTQNGMSKLPHIQQEIEAKLAKLLEERRVQWQQEENTSQRKKLKSRHA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N001</accession>
    <name>A0A1C7N001_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_09600</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000887">
        <property type="protein sequence ID" value="OBZ82351.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N001"/>
    <dbReference type="STRING" id="101091.A0A1C7N001"/>
    <dbReference type="InParanoid" id="A0A1C7N001"/>
    <dbReference type="OrthoDB" id="3981028at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="298"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="189"/>
            <end position="268"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ82351.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="347" mass="39473" checksum="76186E5EF3CFE36E" modified="2016-11-30" version="1">MSAQTLYEKALRSYLLRKYTSASNTCLKALAKQDQADDLLKINIWTLYLNITSTLLETTPFLGINLKSIGIEHASSIEEACRIVWKKVVEGFDGLTNARVISACLVMDLKLNQLTVAKETTEEWLASLPDSYLDQLSTRAKDQEDYIGVIELYSTRILPGLGDFESAEAFVEYNPILSDAKKKSLFSLLNDKKKAIEKERQEKQKHEEAARLAAEEKKREIEKRQLEEARQLEEARQLEKEKEELGKANQLEERREKIAEVKEREIKTAELSTPAPSSRSVANTNKIQQWINQLKSQGIATSGMILFALFALFALLRGQRGRLSAALQRLLNKLWQTVQMGTKVTYM</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N146</accession>
    <name>A0A1C7N146_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_09132</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000781">
        <property type="protein sequence ID" value="OBZ82820.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N146"/>
    <dbReference type="InParanoid" id="A0A1C7N146"/>
    <dbReference type="OrthoDB" id="2286663at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ82820.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="277" mass="31863" checksum="2171A51E6CE24C64" modified="2016-11-30" version="1">MNNLDEKCNLTIFKTKDYVEDFNTGVKSLMTKARLLELSDIHRRWWINEHSQQTDNQEERTVSQRSSWTNCIAALKNAFLLSEGNHKKMSFLVNSLNSMLEEFDNMIDGDSLNPDVGFLPSFEVRTPEKEKAGEEVKVAKELGLKDVQKDESYNDATIEINDDEESPLLIDTTIKKRRKDEKVDEKEIFIPRKRIRATHKTLPFDIHSSIPRNDITEAFGPVGDGYCGFRSASFLVYALEKNKKIYQNSLEMNFEDVEKVIARGIDVETTVTKSNRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N1S5</accession>
    <name>A0A1C7N1S5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Repressible high-affinity phosphate permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">pho-5_0</name>
        <name evidence="10" type="ORF">A0J61_08852</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000722">
        <property type="protein sequence ID" value="OBZ83095.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N1S5"/>
    <dbReference type="FunCoup" id="A0A1C7N1S5">
        <property type="interactions" value="645"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N1S5"/>
    <dbReference type="InParanoid" id="A0A1C7N1S5"/>
    <dbReference type="OrthoDB" id="433512at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005315">
        <property type="term" value="F:phosphate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006817">
        <property type="term" value="P:phosphate ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd17364">
        <property type="entry name" value="MFS_PhT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004738">
        <property type="entry name" value="Phos_permease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00887">
        <property type="entry name" value="2A0109"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24064">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 22 MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00216">
        <property type="entry name" value="SUGAR_TRANSPORT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00217">
        <property type="entry name" value="SUGAR_TRANSPORT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0592">Phosphate transport</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="59"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="90"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="122"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="154"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="187"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="222"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="315"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="355"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="390"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="417"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="455"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="489"/>
            <end position="508"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="9">
        <location>
            <begin position="47"/>
            <end position="512"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="518"/>
            <end position="560"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="519"/>
            <end position="531"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022592"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OBZ83095.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="560" mass="61244" checksum="5D209391D959DA29" modified="2016-11-30" version="1">MNSKETPPATLREGAHSPEPILSAKERRRLALVDIDNAKFGWYHIRACIVSGIGFFTDAYDIFAINLVSIMIGFVYWPNEGNKTPHNVDTAIKVSCSVGTVIGQLLFGYLADHVGRKRMYGVELMIIIIGTIGQTLAGNAFAASFWAVITFWRILVGIGIGGDYPLSSVITAEFATTRHRGAMMAAVFAMQGIGQVTASLVGLIVTAAYKSAIESDQAYLDYVWRIVIGLGAVPGLCALYYRLTIPETPRYTMDIENKFEQGLSDARAFVETGAKSGDYKAPAIATTEEDNEPAIPKASWSDFVRHFSKWKNGKILFGTAYSWFALDVAWYGLGLNNSIILQNIGFAGGPDAYNAVFKACVGNLIINLLGSVPGYWITVFTVDKIGRKTIQIMGFTVLTIMFVILGFGYHAIINTSVALFIVLFTITQIFFNFGPNSTTFIVPGECFPTRYRSTAHGISAASGKIGAIIAQVGFGLLKDIGGSNAWIDHLLEIFAFFMLTGLFSSFLIEETKGKTLEELSGDYDDDDDDERVQEMKPHSSSSNLPSDEMLPNGYSRKIND</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N1V4</accession>
    <name>A0A1C7N1V4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein C16C4.19</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_08860</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000723">
        <property type="protein sequence ID" value="OBZ83090.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N1V4"/>
    <dbReference type="STRING" id="101091.A0A1C7N1V4"/>
    <dbReference type="InParanoid" id="A0A1C7N1V4"/>
    <dbReference type="OrthoDB" id="438080at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005655">
        <property type="term" value="C:nucleolar ribonuclease P complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008033">
        <property type="term" value="P:tRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.20.50.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007175">
        <property type="entry name" value="Rpr2/Snm1/Rpp21"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14742:SF3">
        <property type="entry name" value="RIBONUCLEASE MRP PROTEIN SUBUNIT SNM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14742">
        <property type="entry name" value="RIBONUCLEASE P SUBUNIT P21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04032">
        <property type="entry name" value="Rpr2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="107"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="111"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="127"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="147"/>
            <end position="164"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ83090.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="164" mass="18643" checksum="D73527178481A10D" modified="2016-11-30" version="1">MTTNTLQTHQQTQRLDHLFTAGYSMFTSCPSLSRYYMSEFQNTLIEYDLTSATERLACSSCGQIMVPGLNQKTRLISKRRKNKPNKSTLQITCLTCSRVKVYHGSHKKKLPMSVEQQPSVPVVEPMKKKKKNNNHKNSLKALLSKPKAQQNMTNSNLSDFLSSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N233</accession>
    <name>A0A1C7N233_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Quinate permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">qutD_2</name>
        <name evidence="10" type="ORF">A0J61_08783</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000710">
        <property type="protein sequence ID" value="OBZ83170.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N233"/>
    <dbReference type="STRING" id="101091.A0A1C7N233"/>
    <dbReference type="InParanoid" id="A0A1C7N233"/>
    <dbReference type="OrthoDB" id="508119at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005351">
        <property type="term" value="F:carbohydrate:proton symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000134">
        <property type="entry name" value="MFS sugar transporter protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050360">
        <property type="entry name" value="MFS_Sugar_Transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00879">
        <property type="entry name" value="SP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022:SF2">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00171">
        <property type="entry name" value="SUGRTRNSPORT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="38"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="63"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="98"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="129"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="258"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="287"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="320"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="387"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="9">
        <location>
            <begin position="1"/>
            <end position="413"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OBZ83170.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="465" mass="51612" checksum="F10BFE8868019721" modified="2016-11-30" version="1">MEENTSQIEGNIVSLLQAGACGGALSANFSADRFGRRTSVMFSCLLFMFGSLIQTGAKNLDMILFGRFAGGWGMGACSMLIPMYIAELVPSHYRGRMGALWSLNIAVGMTIAFWTNYGCLINLRGDIQWRLPLGLQAVPGLILFLGMFLLPESIRWLALKDRFDEAKQVLCKLRNLPEDHPDIHAEFEDISNAILAEKHHEGSKWNEMRESYNIRRIVLGCFMQAAQQWTGTNAINYYGPLIFQTVGLKGNTSSLMTGIYGCVKIFFCLVSFLFLDKKGIGRRPILIAGSLANVCIFFILGGMLYAIQHAASTGSEANPAYGYVGLLMIYFFAVSFEFTWGPMTWIVCSEIFPNRIRAACISLTTSMNWAMNAVIGKVTPLMITSIAYATFFFYGACAVLMGCIVFFFLPETQGRSLEQMNEIFNDGRIIVIGHKKLDKSKDLLPTTNSSCSDINEKSILELKAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N2A2</accession>
    <name>A0A1C7N2A2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">AA1-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_08726</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000700">
        <property type="protein sequence ID" value="OBZ83222.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N2A2"/>
    <dbReference type="InParanoid" id="A0A1C7N2A2"/>
    <dbReference type="OrthoDB" id="2433997at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008889436" description="AA1-like domain-containing protein" evidence="1">
        <location>
            <begin position="22"/>
            <end position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ83222.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="138" mass="14842" checksum="5DC0E42DA07C58EA" modified="2016-11-30" version="1">MVALTFSKLAALSAFASLVSAAPFSNCNYFRVTSPTTYFTTTAGECQQVSFDYSGPQPAPIVSIDLHESGTDKFVSTLIQNVTAVGPATPFFNINLNGYNVTGDYYFLVNYGPGCDAIKTQNFHLLYNSNSPPAVCPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N2K6</accession>
    <name>A0A1C7N2K6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">MULE transposase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_08610</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000680">
        <property type="protein sequence ID" value="OBZ83343.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N2K6"/>
    <dbReference type="InParanoid" id="A0A1C7N2K6"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018289">
        <property type="entry name" value="MULE_transposase_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10551">
        <property type="entry name" value="MULE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MULE transposase" evidence="1">
        <location>
            <begin position="6"/>
            <end position="86"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF10551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ83343.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="147" mass="16597" checksum="F3C063B4B6BA3F08" modified="2016-11-30" version="1">MSQVSIIDVIYLTDNVKIPVASIYGVYDIGLDKLMTFSVACAFVSDEKEGTFECFLQQLKNLLIQRTDLASAFQRIDKLESATNYIKSGKLLEGEFAATEHTCWCHARLSHMLPRMLLVPGLEGKLFSFDNIYPRWHLSDLNSVVTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N2K7</accession>
    <name>A0A1C7N2K7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Ras modification protein ERF4</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">GOLGA7</name>
        <name evidence="9" type="ORF">A0J61_08618</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="3">Interacts with ERF2.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ERF4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000681">
        <property type="protein sequence ID" value="OBZ83332.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N2K7"/>
    <dbReference type="STRING" id="101091.A0A1C7N2K7"/>
    <dbReference type="InParanoid" id="A0A1C7N2K7"/>
    <dbReference type="OrthoDB" id="2190159at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031211">
        <property type="term" value="C:endoplasmic reticulum palmitoyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006612">
        <property type="term" value="P:protein targeting to membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019383">
        <property type="entry name" value="Golgin_A_7/ERF4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051371">
        <property type="entry name" value="Ras_palmitoyltransferase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13254">
        <property type="entry name" value="GOLGI AUTOANTIGEN, GOLGIN SUBFAMILY A, 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13254:SF0">
        <property type="entry name" value="GOLGIN SUBFAMILY A MEMBER 7_ERF4 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10256">
        <property type="entry name" value="Erf4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Golgin subfamily A member 7/ERF4" evidence="8">
        <location>
            <begin position="64"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004406"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007732"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011396"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00018463"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF10256"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OBZ83332.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="184" mass="21206" checksum="67CBA7E81D172D92" modified="2016-11-30" version="1">MFATQTCDPITPNKAHLKPDTVSNNKYLDTSILMNNSSTLTTHTSSIQAHQSIPIQHQIPTKTIRIERDYSIGDGITRFSTHFPTELAGKITQEQFTHTITEINRIMDYADRLSWRIVLENLLETLTIYLWPVFFSTHYQRAVKRLLEFIESENTTLYHPQALSISNPVKSAFLFVEISVYETN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N322</accession>
    <name>A0A1C7N322_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_08521</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000665">
        <property type="protein sequence ID" value="OBZ83427.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N322"/>
    <dbReference type="InParanoid" id="A0A1C7N322"/>
    <dbReference type="OrthoDB" id="2276543at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ83427.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="77" mass="8903" checksum="3D7D8C37A0735D1D" modified="2016-11-30" version="1">MHIQGLEDNCFRQEIRMDYNEFKALLGLIKSNKAFQSNGPVPQVERYIRIQTIVALERLATYGNETLVGNASYSYKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N380</accession>
    <name>A0A1C7N380_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="16">Flap endonuclease 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="16" type="primary">FEN1</name>
        <name evidence="16" type="ORF">A0J61_08367</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="14">Belongs to the XPG/RAD2 endonuclease family. FEN1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000636">
        <property type="protein sequence ID" value="OBZ83585.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N380"/>
    <dbReference type="FunCoup" id="A0A1C7N380">
        <property type="interactions" value="175"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N380"/>
    <dbReference type="InParanoid" id="A0A1C7N380"/>
    <dbReference type="OrthoDB" id="31113at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008409">
        <property type="term" value="F:5'-3' exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017108">
        <property type="term" value="F:5'-flap endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.150.20:FF:000009">
        <property type="entry name" value="Flap endonuclease 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.20">
        <property type="entry name" value="5' to 3' exonuclease, C-terminal subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1010">
        <property type="entry name" value="5'-nuclease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036279">
        <property type="entry name" value="5-3_exonuclease_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008918">
        <property type="entry name" value="HhH2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029060">
        <property type="entry name" value="PIN-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006086">
        <property type="entry name" value="XPG-I_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006084">
        <property type="entry name" value="XPG/Rad2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006085">
        <property type="entry name" value="XPG_DNA_repair_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11081:SF9">
        <property type="entry name" value="FLAP ENDONUCLEASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11081">
        <property type="entry name" value="FLAP ENDONUCLEASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00867">
        <property type="entry name" value="XPG_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00752">
        <property type="entry name" value="XPG_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00853">
        <property type="entry name" value="XPGRADSUPER"/>
    </dbReference>
    <dbReference type="SMART" id="SM00279">
        <property type="entry name" value="HhH2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00485">
        <property type="entry name" value="XPGN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47807">
        <property type="entry name" value="5' to 3' exonuclease, C-terminal subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88723">
        <property type="entry name" value="PIN domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0227">DNA damage</keyword>
    <keyword evidence="12" id="KW-0234">DNA repair</keyword>
    <keyword evidence="3" id="KW-0235">DNA replication</keyword>
    <keyword evidence="6 16" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="9" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="4" id="KW-0540">Nuclease</keyword>
    <keyword evidence="13" id="KW-0539">Nucleus</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="XPG N-terminal" evidence="15">
        <location>
            <begin position="1"/>
            <end position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00034726"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="SMART" id="SM00485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="OBZ83585.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="467" mass="53619" checksum="1998DD18350F3578" modified="2016-11-30" version="1">MGVQGLTGILSRYAPKSVRNVSCAAFAAQTIAIDASCHLNKFIYGDEPHAHRHIYGFYQLTRFCDMNNIKPIFVFDGLRRLEAKKLEHAKRERSRRKVKHSLLFEQEQSLRLDNWAEVSDMYDQTGISKESMHAILGEMSDTIDEIEKVEEQQKAPLTDQKAISDEKQFEIESKLTQIAQELRVAIAIAEDSEKYTRTVRDLAKRERELVSDIIVHRSDSLRPALDQLRRDNQAMLQSLEKRSLRVTQRMRDECKDFLQKLGYVCFTCHDHEAEAMCANMGRLGRASAIVSEDTLVFGNSPLLRYFFSKNRQILSIDPIVAREELNLSRDAFVDFCILCGTDFSGTIRGIGPHRALKAIQKYGSIEALTMNLDPRYSPQDTFDYKQARKVFNNLPPIPTEDEAYVPLNTSRAEKRELLEYYDIDPTEVDKKIQNAVLNQSIINHQNWGVNPFLSNTNHLAEQNLLKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N394</accession>
    <name>A0A1C7N394_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">CS domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">A0J61_08388</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the sel-1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000640">
        <property type="protein sequence ID" value="OBZ83562.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N394"/>
    <dbReference type="STRING" id="101091.A0A1C7N394"/>
    <dbReference type="InParanoid" id="A0A1C7N394"/>
    <dbReference type="OrthoDB" id="2254916at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06467">
        <property type="entry name" value="p23_NUDC_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.790">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007052">
        <property type="entry name" value="CS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008978">
        <property type="entry name" value="HSP20-like_chaperone"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006597">
        <property type="entry name" value="Sel1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050767">
        <property type="entry name" value="Sel1_AlgK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11102:SF160">
        <property type="entry name" value="ERAD-ASSOCIATED E3 UBIQUITIN-PROTEIN LIGASE COMPONENT HRD3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11102">
        <property type="entry name" value="SEL-1-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04969">
        <property type="entry name" value="CS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08238">
        <property type="entry name" value="Sel1"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SMART" id="SM00671">
        <property type="entry name" value="SEL1"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81901">
        <property type="entry name" value="HCP-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49764">
        <property type="entry name" value="HSP20-like chaperones"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51203">
        <property type="entry name" value="CS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="502"/>
            <end position="524"/>
        </location>
    </feature>
    <feature type="domain" description="CS" evidence="4">
        <location>
            <begin position="8"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="131"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="467"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="131"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="483"/>
            <end position="492"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00038101"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OBZ83562.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="530" mass="58776" checksum="621261C224EE002A" modified="2016-11-30" version="1">MTENDEQLQTNTYVWSQSSDQVTISFLVPESVKAKDLDINIERQYLTAGLKGHEPVFQAKLFQPINHFESLWQLEKNSMSPFSSLTASPSLSIASSFAFMSSPNHSPNSSMILPPAANTGLSEVSDLLAQTANSPTNSDEDSISQPSSPTLLHTPPAIATPPHLKKPKYRILTIHLEKEDDIAEWAVPVSGPHNKTNTMDVTSSYLLGQWFEARMGNLVKALEYYLSSAERGHTQSMIKAAGIYETNKETAVAKIVPEKDSKKAFEWYKRAADCEQYEPGTEISNGPDPLACYIVGTSYGTGLPEAGVEKDYQSALYYYNRCMTITAPRIDIDFSLLDMDYVPKHKLRSHAPHTRDEHYFCSSAFQTGLIYLYGSQPEGEAVHSTTLVEADPDLAIRYWKEASLLGHAQACYNIGILYANAMGVEQDIWAAGKWFGRAIKLDTTGKLVVPAGVAIVDWDLTKEQHQQQLKKATSKGSNNEEKKKKKKRVKRTKQSDADNNDVVGAIVALSSIVAVAGVAWYFFIREKKST</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N3K1</accession>
    <name>A0A1C7N3K1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Phospholipase</fullName>
            <ecNumber evidence="9">3.1.4.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">pld1_1</name>
        <name evidence="13" type="ORF">A0J61_08732</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 9">
            <text>a 1,2-diacyl-sn-glycero-3-phosphocholine + H2O = a 1,2-diacyl-sn-glycero-3-phosphate + choline + H(+)</text>
            <dbReference type="Rhea" id="RHEA:14445"/>
            <dbReference type="ChEBI" id="CHEBI:15354"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57643"/>
            <dbReference type="ChEBI" id="CHEBI:58608"/>
            <dbReference type="EC" id="3.1.4.4"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Endomembrane system</location>
            <topology evidence="8">Lipid-anchor</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the phospholipase D family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.4.4" evidence="9"/>
    <dbReference type="EMBL" id="LUGH01000701">
        <property type="protein sequence ID" value="OBZ83216.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N3K1"/>
    <dbReference type="STRING" id="101091.A0A1C7N3K1"/>
    <dbReference type="InParanoid" id="A0A1C7N3K1"/>
    <dbReference type="OrthoDB" id="14911at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035091">
        <property type="term" value="F:phosphatidylinositol binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004630">
        <property type="term" value="F:phospholipase D activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035556">
        <property type="term" value="P:intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006654">
        <property type="term" value="P:phosphatidic acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009395">
        <property type="term" value="P:phospholipid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01254">
        <property type="entry name" value="PH_PLD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd09138">
        <property type="entry name" value="PLDc_vPLD1_2_yPLD_like_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd09141">
        <property type="entry name" value="PLDc_vPLD1_2_yPLD_like_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd06093">
        <property type="entry name" value="PX_domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.870.10">
        <property type="entry name" value="Endonuclease Chain A"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1520.10">
        <property type="entry name" value="Phox-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001849">
        <property type="entry name" value="PH_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025202">
        <property type="entry name" value="PLD-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001736">
        <property type="entry name" value="PLipase_D/transphosphatidylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016555">
        <property type="entry name" value="PLipase_D_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015679">
        <property type="entry name" value="PLipase_D_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001683">
        <property type="entry name" value="PX_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036871">
        <property type="entry name" value="PX_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18896:SF76">
        <property type="entry name" value="PHOSPHOLIPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18896">
        <property type="entry name" value="PHOSPHOLIPASE D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00614">
        <property type="entry name" value="PLDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13091">
        <property type="entry name" value="PLDc_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00787">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF009376">
        <property type="entry name" value="Phospholipase_D_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00233">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00155">
        <property type="entry name" value="PLDc"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56024">
        <property type="entry name" value="Phospholipase D/nuclease"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64268">
        <property type="entry name" value="PX domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50035">
        <property type="entry name" value="PLD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50195">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5 9" id="KW-0442">Lipid degradation</keyword>
    <keyword evidence="6" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="7" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="PX" evidence="12">
        <location>
            <begin position="225"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="domain" description="PLD phosphodiesterase" evidence="11">
        <location>
            <begin position="590"/>
            <end position="617"/>
        </location>
    </feature>
    <feature type="domain" description="PLD phosphodiesterase" evidence="11">
        <location>
            <begin position="954"/>
            <end position="981"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="874"/>
            <end position="894"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000798"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022963"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00037868"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRNR" id="PIRNR009376"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="OBZ83216.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="1152" mass="133905" checksum="724ACFFF0C838DE4" modified="2016-11-30" version="1">MSHPISSNMEYLNTMANKSRIGIDESAKDYFSQQPSHFSSSLENQWHSVFRRISLNIQRGESFSKDLIAMNTKSHSFQHRADSASSNLHQGDFDETFEDDTLPNLEDIVQLVASQPMTFTNGYFESPFESDTDTLYFYEEKKVHPLSTDLYDRPHDIKASMSDDTDKAYQHKVHSAEINEGVKVTDPINQTKSSAPYYPFAFAPLYLSLLCRDEHARKAPPILFDALNISITGSIMHQNVSHKLWSFRIDIQYGDIKWFIRRTIIEFYNLHLTLKFKYISGFISEQPPSFPSQLTHLTNAALTSMHIARDQEETLWRDIALKRCDALESYLKELIRRASMTVNYELCEFLELSALSIVKDMGWKGKEGYLDYRICLPSLRLFKWQKWQKEWVILRDSYVAFCEDISSRIPTDVLLFDRHVKFTQTQGAFGTHLVISNTSKQIEIKAPTSRYMDEWIEMFSKVQTESPWMMNHRFGSFAPIRKNANVKWFVDGQDYFEAVAEAILSAKSEIFIEDWWLSPQLYLRRPPKGNEEYRLDRLLKRKACEGVMIYIVLYKNVSVALPLDSQHTQGWMHQIHPNIIVQRHSNLTSPLWAHHEKILVIDSRLAFVGGLDLCFGRYDTTEHALMDYPANNIKEVFPGQDYSNPRIKDFEKVSQYDRELVDKQYTPRMPWHDVHTVMSGPPARDVARHFVQRWNFVKSNREGVPFLLPKGEYVSPRDERKFKGSCRIQVLRSSARWSQGIAREHSIYNAYMECIFKAKHFIYIENQFFITTTDPENKLIKNKIGQAIVERIKRAHKDNQAFKVIVIIPIAPGFEGDFVQNNKQSMALRSVAQYQYSSISRGKYSIFEQLKKANIPVDKYISFYSLRNWDKSKPGVSEHNSGPIPVQTSAHSSPELAPSGYNLRLLNKKKMRSRSLSQSKSLNETIQMRQQVTSIPFMDPQNIIDHKKTFFVTEQVYIHSKLMIVDDKIAICGSANLNDRSQLGNRDSELVVIVEDTDMIDSRMNGRPYKAAKFAFTLRMQLFKEHLGLLNQGNNSYHLIKDDDLMDPLDLDFYSRIWNKIAEKNTLIYREMFRCVPDNTVHSIEQHRQFVPDPNRVLPGHIAEPWKYTDEQILFELSQIQGHLVEFPIDYLKDVNLTASMMQEAVPPIVFT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N407</accession>
    <name>A0A1C7N407_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_08584</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000675">
        <property type="protein sequence ID" value="OBZ83369.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N407"/>
    <dbReference type="InParanoid" id="A0A1C7N407"/>
    <dbReference type="OrthoDB" id="424012at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="104"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="174"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="272"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="120"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="193"/>
            <end position="208"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ83369.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="291" mass="32529" checksum="B8B24FCF37F9085D" modified="2016-11-30" version="1">MKRFGQEDVGNNDTKRLKENTTHVGESTENMPGHLEQTATTLGSLPVVETIVLSSDDEDEQKTVHLPLDIEQEIDAEIDALMPLTVGIKSNKDTEVVMATKKSLVPSDDEASEISRNELDELDSTGDEEETTSTKPLITTTIAAAAVETTAHPHFSFFAPRSVPTSEPKPVYTIKLNPPKPQSVVEEEEIGISSPTKRQPARQSRNRVSTYNDLENSVNLEQLLEHQEPQSMQFIRRAPKSKPTVVEQLVPLNRRRSLKTGFVYDTAMSYHATPDPMEIHPEDPRMQAYQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N4V8</accession>
    <name>A0A1C7N4V8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_07869</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000558">
        <property type="protein sequence ID" value="OBZ84081.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N4V8"/>
    <dbReference type="STRING" id="101091.A0A1C7N4V8"/>
    <dbReference type="InParanoid" id="A0A1C7N4V8"/>
    <dbReference type="OrthoDB" id="2258642at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="94"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="271"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="18"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="125"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="181"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="233"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="248"/>
            <end position="260"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ84081.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="533" mass="60861" checksum="243CC95E39ED7C93" modified="2016-11-30" version="1">MSSSPKFWQKLGLRKQNKSLSSSTTNSDNTSIRSSASLYTIHDAPSETNGKQMKRFRQAYNLRLRSRASFTSLRQQPIVDNAVRPAFVKPAIRKPAVDSEESAESNMMSDLEDDHHPNMTHNKKSSIPSLVSSDYNLKKYTTPQPTRKQSCADLPNNNSAISKLPSPRVMKKTKSNQSLKSVSSASSRPGSADQKTKSKSVQSGTPIIKRKSIPKLDQKQSQTISSDEDDTKSNLTRSSSYSSIIDKRSKKKSSHDKKKSQSTEAGDNFVLDMLRDELEKEKAASRALLGQKEAIAKDLDYFCKLVDEVTDEKDEFKQKYEEEKTQNELLRKSLRNMQPSCNSIAKLDTEFLQQLSQENEEMYTLSRQLQSKDDEIISLRNDLKQTQSQLQILRKIMEQMLRTDGRESEDASFSQESDDMKSLLLQASYHPNTETPPSPTPCYVISDTTEDDDDLMSTTSRDSYHSNKNHFFRPQYDFLKYDNLTEQIAKKKSEDYSKKIALSRRRKNQIEEMLGEVDMQLNRVRQKIRTPSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N558</accession>
    <name>A0A1C7N558_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Eukaryotic translation initiation factor 6</fullName>
            <shortName evidence="5">eIF-6</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">tif6</name>
        <name evidence="5" type="synonym">TIF6</name>
        <name evidence="6" type="ORF">A0J61_07721</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. Is also involved in ribosome biogenesis. Associates with pre-60S subunits in the nucleus and is involved in its nuclear export.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Monomer. Associates with the 60S ribosomal subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="5">Nucleus</location>
            <location evidence="5">Nucleolus</location>
        </subcellularLocation>
        <text evidence="5">Shuttles between cytoplasm and nucleus/nucleolus.</text>
    </comment>
    <comment type="PTM">
        <text evidence="5">Phosphorylation at Ser-174 and Ser-175 promotes nuclear export.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the eIF-6 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000538">
        <property type="protein sequence ID" value="OBZ84230.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N558"/>
    <dbReference type="FunCoup" id="A0A1C7N558">
        <property type="interactions" value="579"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N558"/>
    <dbReference type="InParanoid" id="A0A1C7N558"/>
    <dbReference type="OrthoDB" id="4155914at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030687">
        <property type="term" value="C:preribosome, large subunit precursor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043023">
        <property type="term" value="F:ribosomal large subunit binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902626">
        <property type="term" value="P:assembly of large subunit precursor of preribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042256">
        <property type="term" value="P:cytosolic ribosome assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000466">
        <property type="term" value="P:maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000463">
        <property type="term" value="P:maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000054">
        <property type="term" value="P:ribosomal subunit export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00527">
        <property type="entry name" value="IF6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.75.10.10:FF:000001">
        <property type="entry name" value="Eukaryotic translation initiation factor 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.75.10.10">
        <property type="entry name" value="L-arginine/glycine Amidinotransferase, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00032">
        <property type="entry name" value="eIF_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002769">
        <property type="entry name" value="eIF6"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00323">
        <property type="entry name" value="eIF-6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10784">
        <property type="entry name" value="TRANSLATION INITIATION FACTOR 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01912">
        <property type="entry name" value="eIF-6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006413">
        <property type="entry name" value="IF-6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00654">
        <property type="entry name" value="eIF6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55909">
        <property type="entry name" value="Pentein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 5 6" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="4 5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="3 5" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0690">Ribosome biogenesis</keyword>
    <feature type="modified residue" description="Phosphoserine; by CK1" evidence="5">
        <location>
            <position position="174"/>
        </location>
    </feature>
    <feature type="modified residue" description="Phosphoserine; by CK1" evidence="5">
        <location>
            <position position="175"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03132"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OBZ84230.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="245" mass="26414" checksum="F01F62F15776977E" modified="2016-11-30" version="1">MAVRAQFENSNEIGVFSRLTNSYCLVALGGSENFYSVFEGELGDVIPVVHTSIAGTRIVGRLTAGNKNGLLVPSTTTDQELQHLRNSLPDNIAVQRVEERLSALGNVIACNDYVALVHPDIDRETEEIIADTLQVEVFRQTVADNVLVGSFCALSNQGGLVHPRTSVQDQDELSSLLQIPLVAGTVNRGSDVIGAGCVVNDWCAFAGMDTTSTELSVMESIFKLQDAQPTAIVNQLRDTLVDTYS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-06-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N5C1</accession>
    <name>A0A1C7N5C1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_07627</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000525">
        <property type="protein sequence ID" value="OBZ84322.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N5C1"/>
    <dbReference type="InParanoid" id="A0A1C7N5C1"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ84322.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="111" mass="11942" checksum="A38E553B3EDD56A3" modified="2016-11-30" version="1">MSSSYLALSLLEGTGSITLAAPVMSLTLEEMSVVGLLNESPCTLSRGLSTSFLSLQGVRSGIGFMSKNTASFERRSVTFENTIIVQDESRFDATRLMSCDVDEVTQATALY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N5M5</accession>
    <name>A0A1C7N5M5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_09292</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000818">
        <property type="protein sequence ID" value="OBZ82654.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N5M5"/>
    <dbReference type="InParanoid" id="A0A1C7N5M5"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="37"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ82654.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="60" mass="5698" checksum="8E8515AA66721F20" modified="2016-11-30" version="1" fragment="single">MSQPPVPPSQQPPVPPPGAFPPGMPPAGFPPAGFSAGPPPPGGFPPAGFPPGGFPPPPAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N5Q3</accession>
    <name>A0A1C7N5Q3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">RNA polymerase II subunit A C-terminal domain phosphatase SSU72</fullName>
            <shortName evidence="9">CTD phosphatase SSU72</shortName>
            <ecNumber evidence="9">3.1.3.16</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">SSU72</name>
        <name evidence="10" type="ORF">A0J61_07489</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Component of the cleavage and polyadenylation factor (CPF) complex, which plays a key role in polyadenylation-dependent pre-mRNA 3'-end formation and cooperates with cleavage factors including the CFIA complex and NAB4/CFIB. SSU72 is required for 3'-end formation of snoRNAs.</text>
    </comment>
    <comment type="function">
        <text evidence="9">Processively dephosphorylates Ser-5 of the heptad repeats YSPTSPS in the C-terminal domain of the largest RNA polymerase II subunit (RPB1).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>O-phospho-L-seryl-[protein] + H2O = L-seryl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:20629"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="EC" id="3.1.3.16"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8 12">
            <text>O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:47004"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="EC" id="3.1.3.16"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="9">Component of the cleavage and polyadenylation factor (CPF) complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the SSU72 phosphatase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.16" evidence="9"/>
    <dbReference type="EMBL" id="LUGH01000507">
        <property type="protein sequence ID" value="OBZ84463.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N5Q3"/>
    <dbReference type="FunCoup" id="A0A1C7N5Q3">
        <property type="interactions" value="624"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N5Q3"/>
    <dbReference type="InParanoid" id="A0A1C7N5Q3"/>
    <dbReference type="OrthoDB" id="57957at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000785">
        <property type="term" value="C:chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005847">
        <property type="term" value="C:mRNA cleavage and polyadenylation specificity factor complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004725">
        <property type="term" value="F:protein tyrosine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0180007">
        <property type="term" value="F:RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030643">
        <property type="term" value="P:intracellular phosphate ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031124">
        <property type="term" value="P:mRNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032215">
        <property type="term" value="P:positive regulation of telomere maintenance via semi-conservative replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090052">
        <property type="term" value="P:regulation of pericentric heterochromatin formation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902801">
        <property type="term" value="P:regulation of siRNA-independent facultative heterochromatin formation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009302">
        <property type="term" value="P:sno(s)RNA transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030847">
        <property type="term" value="P:termination of RNA polymerase II transcription, exosome-dependent"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030846">
        <property type="term" value="P:termination of RNA polymerase II transcription, poly(A)-coupled"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031564">
        <property type="term" value="P:transcription antitermination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006368">
        <property type="term" value="P:transcription elongation by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001174">
        <property type="term" value="P:transcriptional start site selection at RNA polymerase II promoter"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.2300:FF:000039">
        <property type="entry name" value="RNA polymerase II subunit A C-terminal domain phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006811">
        <property type="entry name" value="RNA_pol_II_suA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20383">
        <property type="entry name" value="RNA POLYMERASE II SUBUNIT A C-TERMINAL DOMAIN PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04722">
        <property type="entry name" value="Ssu72"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 9" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="6 9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5 9" id="KW-0904">Protein phosphatase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008978"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047761"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00048336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU369031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OBZ84463.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="191" mass="21695" checksum="7958954D7AD83784" modified="2016-11-30" version="1">MAKYAVICASNQNRSMEAHHVLNKKGFNVHSYGTGTMVRLPGPAIDKPNIYPFGTPYEQVYQELKSKDQALYTQNGLLNMLDRNRKTKEAPQRWHESKETFDVIITCEERCFDSVVEDLANRGQNVNQSTHVINVEIRDNHEDALLGGRAILHLAQMIEASNDIDADMDGIIEEFSMRNPGFPILHTVAYF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N5R3</accession>
    <name>A0A1C7N5R3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 8">cAMP-dependent protein kinase regulatory subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">pkar_2</name>
        <name evidence="12" type="ORF">A0J61_07611</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="8">Tetramer, composed of 2 regulatory (R) and 2 catalytic (C) subunits. In the presence of cAMP it dissociates into 2 active monomeric C subunits and an R dimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 8">Belongs to the cAMP-dependent kinase regulatory chain family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000523">
        <property type="protein sequence ID" value="OBZ84338.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N5R3"/>
    <dbReference type="FunCoup" id="A0A1C7N5R3">
        <property type="interactions" value="375"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N5R3"/>
    <dbReference type="InParanoid" id="A0A1C7N5R3"/>
    <dbReference type="OrthoDB" id="417078at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005952">
        <property type="term" value="C:cAMP-dependent protein kinase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030552">
        <property type="term" value="F:cAMP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004862">
        <property type="term" value="F:cAMP-dependent protein kinase inhibitor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034236">
        <property type="term" value="F:protein kinase A catalytic subunit binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033554">
        <property type="term" value="P:cellular response to stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd00038">
        <property type="entry name" value="CAP_ED"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="CDD" id="cd12098">
        <property type="entry name" value="DD_R_ScPKA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.120.10:FF:000039">
        <property type="entry name" value="cAMP-dependent protein kinase regulatory subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.890.10">
        <property type="entry name" value="cAMP-dependent protein kinase regulatory subunit, dimerization-anchoring domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="entry name" value="Jelly Rolls"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050503">
        <property type="entry name" value="cAMP-dep_PK_reg_su-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012198">
        <property type="entry name" value="cAMP_dep_PK_reg_su"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003117">
        <property type="entry name" value="cAMP_dep_PK_reg_su_I/II_a/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018488">
        <property type="entry name" value="cNMP-bd_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000595">
        <property type="entry name" value="cNMP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018490">
        <property type="entry name" value="cNMP-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11635">
        <property type="entry name" value="CAMP-DEPENDENT PROTEIN KINASE REGULATORY CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11635:SF152">
        <property type="entry name" value="CAMP-DEPENDENT PROTEIN KINASE TYPE I REGULATORY SUBUNIT-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00027">
        <property type="entry name" value="cNMP_binding"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02197">
        <property type="entry name" value="RIIa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000548">
        <property type="entry name" value="PK_regulatory"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00103">
        <property type="entry name" value="CAMPKINASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00100">
        <property type="entry name" value="cNMP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00394">
        <property type="entry name" value="RIIa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51206">
        <property type="entry name" value="cAMP-binding domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47391">
        <property type="entry name" value="Dimerization-anchoring domain of cAMP-dependent PK regulatory subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00888">
        <property type="entry name" value="CNMP_BINDING_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00889">
        <property type="entry name" value="CNMP_BINDING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50042">
        <property type="entry name" value="CNMP_BINDING_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8 9" id="KW-0114">cAMP</keyword>
    <keyword evidence="4 8 9" id="KW-0116">cAMP-binding</keyword>
    <keyword evidence="12" id="KW-0418">Kinase</keyword>
    <keyword evidence="6 8 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="12" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Cyclic nucleotide-binding" evidence="11">
        <location>
            <begin position="153"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="domain" description="Cyclic nucleotide-binding" evidence="11">
        <location>
            <begin position="271"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="79"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="81"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="92"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="114"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="218"/>
        </location>
        <ligand>
            <name>3',5'-cyclic AMP</name>
            <dbReference type="ChEBI" id="CHEBI:58165"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="227"/>
        </location>
        <ligand>
            <name>3',5'-cyclic AMP</name>
            <dbReference type="ChEBI" id="CHEBI:58165"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="337"/>
        </location>
        <ligand>
            <name>3',5'-cyclic AMP</name>
            <dbReference type="ChEBI" id="CHEBI:58165"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="346"/>
        </location>
        <ligand>
            <name>3',5'-cyclic AMP</name>
            <dbReference type="ChEBI" id="CHEBI:58165"/>
            <label>2</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005753"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00020355"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022566"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRNR" id="PIRNR000548"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR000548-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="OBZ84338.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="394" mass="45080" checksum="A8BA434FDCF5EC33" modified="2016-11-30" version="1">MSRESYSSQKHEYQALMNELNKQVIQNQPEDVLQFCFNFFLQRLNNERSKVRDQTHWTQDVITHPSDSFMRETTPMITTTEPDEEEEEENDSVSQDLPQFISTGFPKNRRVSVSAESMQPSLSNQSKKKKKGLQKKPEAEADLIAHSLQNHFLFRTVEQEQLQDVIDSMEEKRFKAGSFVIEQGAVGDYFYIVSEGTLDCFVDDKKVTEYHRGGSFGELALMYNAPRAATIQATSDAILWALDRISFRSMLMETNAEKRQLHEKFLEYVPLLKSLELAERHKIADALEPVWFHDGDVVLRQGDPGESFYLIEKGTAVCYYQKPGFDTQEQVNELKKELALIHDKPRAATVVAKGDLKCVTLGKAAFIRLLGPVMDILKRNTANYHAILQQADQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N6A5</accession>
    <name>A0A1C7N6A5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Transcriptional activator cubitus interruptus</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">ci</name>
        <name evidence="9" type="ORF">A0J61_07280</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000483">
        <property type="protein sequence ID" value="OBZ84673.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N6A5"/>
    <dbReference type="STRING" id="101091.A0A1C7N6A5"/>
    <dbReference type="InParanoid" id="A0A1C7N6A5"/>
    <dbReference type="OrthoDB" id="654211at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:002343">
        <property type="entry name" value="Zinc finger protein 33A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043359">
        <property type="entry name" value="GLI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056436">
        <property type="entry name" value="Znf-C2H2_ZIC1-5/GLI1-3-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45718">
        <property type="entry name" value="TRANSCRIPTIONAL ACTIVATOR CUBITUS INTERRUPTUS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45718:SF4">
        <property type="entry name" value="TRANSCRIPTIONAL ACTIVATOR CUBITUS INTERRUPTUS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23561">
        <property type="entry name" value="zf-C2H2_15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 7" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="8">
        <location>
            <begin position="202"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="8">
        <location>
            <begin position="235"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="8">
        <location>
            <begin position="265"/>
            <end position="295"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OBZ84673.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="313" mass="35845" checksum="1E135D8BBB01A05E" modified="2016-11-30" version="1">MYAQTTDRLIELPMYPSIESTLPPCTFTLNTIDSPLPYPSLENWTVSHLDLINHYPRSDTSSSSGTPDMNLYEPQLLCLLNNFSFPSATLMTERSDSNFSMLYDTNQLVPSLSCQDRDFSFELSPDTITSISSKSDNSSFESQVNPYFVLYQDTNSTVSNSSEDTHPMHSCQWSDCTEMAVSLDQLMTHICDQHIGSGKAAYLCEWKDCGRNKKPFMKRHKMHNHMRTHTGEKPFVCTIDNCKKTFSRPDSLSTHVKTHSDVRPYFCTYPECDKAYFHSRSLRKHIKSIHLKKSTLVRRITSPLTMVAQQQKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N773</accession>
    <name>A0A1C7N773_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">40S ribosomal protein S22</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">RPS22A_1</name>
        <name evidence="5" type="ORF">A0J61_06963</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the universal ribosomal protein uS8 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000446">
        <property type="protein sequence ID" value="OBZ84983.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N773"/>
    <dbReference type="FunCoup" id="A0A1C7N773">
        <property type="interactions" value="458"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N773"/>
    <dbReference type="InParanoid" id="A0A1C7N773"/>
    <dbReference type="OrthoDB" id="10250260at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1370.30:FF:000001">
        <property type="entry name" value="40S ribosomal protein S15a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1490.10:FF:000002">
        <property type="entry name" value="40S ribosomal protein S15a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1370.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01302_A">
        <property type="entry name" value="Ribosomal_uS8_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000630">
        <property type="entry name" value="Ribosomal_uS8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047863">
        <property type="entry name" value="Ribosomal_uS8_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035987">
        <property type="entry name" value="Ribosomal_uS8_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003115">
        <property type="entry name" value="PRK04034.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11758">
        <property type="entry name" value="40S RIBOSOMAL PROTEIN S15A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00410">
        <property type="entry name" value="Ribosomal_S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56047">
        <property type="entry name" value="Ribosomal protein S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00053">
        <property type="entry name" value="RIBOSOMAL_S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 5" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003660"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OBZ84983.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="130" mass="14725" checksum="9702972B6D8A47CC" modified="2016-11-30" version="1">MVRVSVLNDCLNSINNAEKRGKRQVLVRPSSKVIIKFLSVMQKHGYIGEFEIVDDHRSGKIVIQLIGRINKCGVISPRFNIKYSELEKWTANLLPARQFGHLVLTTSAGIMDQDEARQKHVGGKILGFFY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N7I2</accession>
    <name>A0A1C7N7I2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Myb-like protein A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">mybA</name>
        <name evidence="8" type="ORF">A0J61_06851</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000434">
        <property type="protein sequence ID" value="OBZ85100.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N7I2"/>
    <dbReference type="STRING" id="101091.A0A1C7N7I2"/>
    <dbReference type="InParanoid" id="A0A1C7N7I2"/>
    <dbReference type="OrthoDB" id="2143914at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019185">
        <property type="term" value="C:snRNA-activating protein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001006">
        <property type="term" value="F:RNA polymerase III type 3 promoter sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042795">
        <property type="term" value="P:snRNA transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042796">
        <property type="term" value="P:snRNA transcription by RNA polymerase III"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00167">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051575">
        <property type="entry name" value="Myb-like_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017930">
        <property type="entry name" value="Myb_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001005">
        <property type="entry name" value="SANT/Myb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017884">
        <property type="entry name" value="SANT_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46621">
        <property type="entry name" value="SNRNA-ACTIVATING PROTEIN COMPLEX SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46621:SF1">
        <property type="entry name" value="SNRNA-ACTIVATING PROTEIN COMPLEX SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13921">
        <property type="entry name" value="Myb_DNA-bind_6"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00249">
        <property type="entry name" value="Myb_DNA-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00717">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="10"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51294">
        <property type="entry name" value="HTH_MYB"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50090">
        <property type="entry name" value="MYB_LIKE"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51293">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH myb-type" evidence="7">
        <location>
            <begin position="1"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="domain" description="Myb-like" evidence="5">
        <location>
            <begin position="1"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="domain" description="Myb-like" evidence="5">
        <location>
            <begin position="49"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="domain" description="HTH myb-type" evidence="7">
        <location>
            <begin position="53"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="domain" description="Myb-like" evidence="5">
        <location>
            <begin position="106"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="domain" description="HTH myb-type" evidence="7">
        <location>
            <begin position="110"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="domain" description="Myb-like" evidence="5">
        <location>
            <begin position="159"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="domain" description="SANT" evidence="6">
        <location>
            <begin position="162"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="domain" description="HTH myb-type" evidence="7">
        <location>
            <begin position="164"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="domain" description="Myb-like" evidence="5">
        <location>
            <begin position="317"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="domain" description="HTH myb-type" evidence="7">
        <location>
            <begin position="371"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="domain" description="Myb-like" evidence="5">
        <location>
            <begin position="371"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="domain" description="HTH myb-type" evidence="7">
        <location>
            <begin position="432"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="domain" description="Myb-like" evidence="5">
        <location>
            <begin position="495"/>
            <end position="548"/>
        </location>
    </feature>
    <feature type="domain" description="HTH myb-type" evidence="7">
        <location>
            <begin position="523"/>
            <end position="552"/>
        </location>
    </feature>
    <feature type="domain" description="Myb-like" evidence="5">
        <location>
            <begin position="549"/>
            <end position="605"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51293"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OBZ85100.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="613" mass="72616" checksum="247CAF3E9A6E112D" modified="2016-11-30" version="1">MAEKWQPWEDELLSNYVKHNGKKWTEFVQHCLPHRSSKQCEARWSDMLDPRLKQGPFSIQEKQKLREAVGKLGEGRWAEISREYLPERSPRRIANVWSSLSSASEEIANKHKRWTPEEDQLLLQGIDKYGYSAWTKIASEFLPWRSRMQIRNHYLVKLDPNVSKEKWTDDELDLLLRRTIIFGQKWNKVAEGIPKRSPEQCSRIWMTQLDPGLNKEPWTSEETLLFWKQLVECKGNFVEVSEKLPGRTRMMCFEKFWSTVKKDPEFCLVGGDRIEQKKQENAPEWRTRIASLVCEWLEHDMSIREASNGALYVHYPGKWSQDELDKLKKVVDQEKSGLGELDSEAWKRIALHFDGRNAEQSKYQYQAHAVNNDKKKGTWSEEEDSLLEKLIKEHGTSNWDRIIRAIPHRSQRQCAYRWYHYLQYKNREGEETQIVRHKRLTETEKLLIQEGVDMFGTDWHAIHMVYLPTRTPKQMASWWYAHTQKQQAYSEDISKNRKWTEEEDKVLNFAVQSNIDTTTGQVPSWAKVAKMIQGRTSSQCRVRWMYSLRPGLLKGIWSYDEELRLVDIVQKYRFEAIHINWATVAGELGTGRSEWACRCKYNYMQKKGNRFAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N7T2</accession>
    <name>A0A1C7N7T2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">SWR1 complex subunit vps71</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">vps71_1</name>
        <name evidence="7" type="synonym">vps71_0</name>
        <name evidence="6" type="ORF">A0J61_06746</name>
        <name evidence="7" type="ORF">A0J61_06748</name>
    </gene>
    <organism evidence="6 8">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 8" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000422">
        <property type="protein sequence ID" value="OBZ85205.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="LUGH01000422">
        <property type="protein sequence ID" value="OBZ85209.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N7T2"/>
    <dbReference type="FunCoup" id="A0A1C7N7T2">
        <property type="interactions" value="29"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N7T2"/>
    <dbReference type="InParanoid" id="A0A1C7N7T2"/>
    <dbReference type="OrthoDB" id="74807at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006338">
        <property type="term" value="P:chromatin remodeling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd21437">
        <property type="entry name" value="zf-HIT_ZNHIT1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.60.190">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039723">
        <property type="entry name" value="Vps71/ZNHIT1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007529">
        <property type="entry name" value="Znf_HIT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13093">
        <property type="entry name" value="ZINC FINGER HIT DOMAIN CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04438">
        <property type="entry name" value="zf-HIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144232">
        <property type="entry name" value="HIT/MYND zinc finger-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51083">
        <property type="entry name" value="ZF_HIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="HIT-type" evidence="5">
        <location>
            <begin position="106"/>
            <end position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00453"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51083"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OBZ85205.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OBZ85209.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="143" mass="16181" checksum="12D85FE1C52FDC8B" modified="2016-11-30" version="1">MSKRVKYTHHDPEIHSKHLKRQLDSLEKDNHQPLSDVEGLISIALAAQEEETGTTGISSRKSRNRSTNVHSAKANLTMLLEEAPVTPYCYQTCAVAPSLYPPRKFCSVCGFQSDYTCLRCGMKYCSTRCLSTHRETRCLKWTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N807</accession>
    <name>A0A1C7N807_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Small-subunit processome Utp12 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">A0J61_06714</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the UTP5 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000419">
        <property type="protein sequence ID" value="OBZ85233.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N807"/>
    <dbReference type="STRING" id="101091.A0A1C7N807"/>
    <dbReference type="InParanoid" id="A0A1C7N807"/>
    <dbReference type="OrthoDB" id="30195at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000462">
        <property type="term" value="P:maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007148">
        <property type="entry name" value="SSU_processome_Utp12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052414">
        <property type="entry name" value="U3_snoRNA-assoc_WDR"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44267">
        <property type="entry name" value="WD REPEAT-CONTAINING PROTEIN 43"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44267:SF1">
        <property type="entry name" value="WD REPEAT-CONTAINING PROTEIN 43"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04003">
        <property type="entry name" value="Utp12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Small-subunit processome Utp12" evidence="5">
        <location>
            <begin position="63"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="157"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="157"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="172"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="207"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="218"/>
            <end position="236"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00038335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF04003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OBZ85233.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="236" mass="27273" checksum="F96F3F0F708C5E13" modified="2016-11-30" version="1">MGKKGSKQNNTTEVRRGSINNTDITIVNHNETDHSKFSVACTPTEKEQTSQPWQELKKGIQSVDDMRKRVRQLPLDHVLPLLKELLDSFEKDPTARDTTEWLKVVLLTHTAYFMSQPDTVQRLSNVYKALDDRLTAYPKLLAMHGRLDLVQNQVEARRRRENASDDEHALDTEDEEDEEDDEEDQSESEIEDDDEDIESDEDDNLMEMDHDNEMFKEEEQDSGSEEEAVSSDSDLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N860</accession>
    <name>A0A1C7N860_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Reverse transcriptase RNase H-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_07140</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000466">
        <property type="protein sequence ID" value="OBZ84809.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N860"/>
    <dbReference type="STRING" id="101091.A0A1C7N860"/>
    <dbReference type="InParanoid" id="A0A1C7N860"/>
    <dbReference type="OrthoDB" id="2205097at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="222"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="239"/>
            <end position="249"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ84809.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="272" mass="31381" checksum="FEDACA8ED04DABA9" modified="2016-11-30" version="1">MLDKEIGIQQEADRASRVKSEYLCERIGYRRGKASETIQTNGYWTNEAREASINAHELKTILFVVKPHAEKYKNSTIHIHIDNITALKHAKRSEWTTLALLQMLALEFQQIMIVYNIQIHFFSPPRNQECTSGQIEHNPEANLQMDTTKKILQVNSTPMKGDDRWICNQKNRRLKQFWILMPEALAHNAFNKQSLKEGLYAHPSWKLMQKVLKKGEERQGQINGVGDANVHNGDKHNQVESLTALSQQEAKADPLVDYQDAQLRKRYFGSSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N8Q1</accession>
    <name>A0A1C7N8Q1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Proteasome assembly chaperone 4</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_06443</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000389">
        <property type="protein sequence ID" value="OBZ85502.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N8Q1"/>
    <dbReference type="STRING" id="101091.A0A1C7N8Q1"/>
    <dbReference type="InParanoid" id="A0A1C7N8Q1"/>
    <dbReference type="OrthoDB" id="368507at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043248">
        <property type="term" value="P:proteasome assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032157">
        <property type="entry name" value="PAC4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33559">
        <property type="entry name" value="PROTEASOME ASSEMBLY CHAPERONE 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33559:SF1">
        <property type="entry name" value="PROTEASOME ASSEMBLY CHAPERONE 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16093">
        <property type="entry name" value="PAC4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ85502.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="102" mass="11506" checksum="A80B58A9F25F2276" modified="2016-11-30" version="1">MTEPIFFQVVQMSSAVFVWIGKTEGKLGDFSVAVPPFGSQTHASATSLFNKGVTEQSRNLSRRLASKYKQQFYVSLDLQSPDDMLFVFVEKKLTEMLKHLLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N8S4</accession>
    <name>A0A1C7N8S4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Cyclase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_06436</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the Cyclase 1 superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000388">
        <property type="protein sequence ID" value="OBZ85520.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N8S4"/>
    <dbReference type="STRING" id="101091.A0A1C7N8S4"/>
    <dbReference type="InParanoid" id="A0A1C7N8S4"/>
    <dbReference type="OrthoDB" id="5396at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004061">
        <property type="term" value="F:arylformamidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019441">
        <property type="term" value="P:L-tryptophan catabolic process to kynurenine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.30.50">
        <property type="entry name" value="Putative cyclase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007325">
        <property type="entry name" value="KFase/CYL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037175">
        <property type="entry name" value="KFase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34861">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34861:SF11">
        <property type="entry name" value="CYCLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04199">
        <property type="entry name" value="Cyclase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102198">
        <property type="entry name" value="Putative cyclase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ85520.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="316" mass="35714" checksum="CCA5828DB314B18B" modified="2016-11-30" version="1">MLPTYDQLPIDKKYPPKTAWGVWGDDDNYGTLNLLTEERVLSASRSIHRGAIFPLNWKLELPKTPFFERSAIQHEYKPMALDSLAFDDVYRDFNTQSSSQWDGLRHVAHMPSKLFYNGVQPEHVAKGSSISEGRLGIHHAARRGIAGRAVLLDYGRWAEKHRPSFDPLERIEITVQELDEVAKAQSVMFEEGDILLLRTGWIQAYEKNHDKITDLMNPPAAGIKACEDTYRWLWNNHFAAVASDSIAFEAFPVHNWEDSCHSFLLGGIGCFIGEMFDLDKLAQDSADDNNYVSFFTSAPLNKENGVATPPNAICIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N8V1</accession>
    <name>A0A1C7N8V1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Vacuolar protein-sorting-associated protein 25</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">ESCRT-II complex subunit VPS25</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">vps25</name>
        <name evidence="8" type="ORF">A0J61_06373</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the VPS25 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000382">
        <property type="protein sequence ID" value="OBZ85575.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N8V1"/>
    <dbReference type="FunCoup" id="A0A1C7N8V1">
        <property type="interactions" value="296"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N8V1"/>
    <dbReference type="InParanoid" id="A0A1C7N8V1"/>
    <dbReference type="OrthoDB" id="245150at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000814">
        <property type="term" value="C:ESCRT II complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042803">
        <property type="term" value="F:protein homodimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005198">
        <property type="term" value="F:structural molecule activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016236">
        <property type="term" value="P:macroautophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043328">
        <property type="term" value="P:protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.10:FF:000141">
        <property type="entry name" value="vacuolar protein-sorting-associated protein 25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.570:FF:000003">
        <property type="entry name" value="Vacuolar protein-sorting-associated protein 25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.570">
        <property type="entry name" value="Winged helix' DNA-binding domain. Chain C. Domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008570">
        <property type="entry name" value="ESCRT-II_cplx_Vps25-sub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014041">
        <property type="entry name" value="ESCRT-II_cplx_Vps25-sub_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13149">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN VPS25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13149:SF0">
        <property type="entry name" value="VACUOLAR PROTEIN-SORTING-ASSOCIATED PROTEIN 25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05871">
        <property type="entry name" value="ESCRT-II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009674"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00017934"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00030094"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OBZ85575.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="186" mass="21725" checksum="B34E015A1EA6925D" modified="2016-11-30" version="1">MSQLEYPTLYDFPPFFTRQVTDATWKSQVAQWESLILAYARQNKLFRLDIHQATTPGGYMIFENKKINRRLSFETLQNIIDEMTTRGTAEWDGPSRTLKTEALIYWHTPEDWANLIWTWMNETGQNNQIVTCYEIAHGELAEDQEFFQLDTAILMKALQVLVKRGHAQMFKGTDEDSMGVKFFGPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N9I9</accession>
    <name>A0A1C7N9I9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">DnaJ subfamily C member 28</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">Dnajc28</name>
        <name evidence="3" type="ORF">A0J61_06189</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000362">
        <property type="protein sequence ID" value="OBZ85765.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N9I9"/>
    <dbReference type="STRING" id="101091.A0A1C7N9I9"/>
    <dbReference type="InParanoid" id="A0A1C7N9I9"/>
    <dbReference type="OrthoDB" id="547796at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018961">
        <property type="entry name" value="DnaJ_homolog_subfam-C_membr-28"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39394:SF1">
        <property type="entry name" value="DNAJ HOMOLOGUE SUBFAMILY C MEMBER 28 CONSERVED DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39394">
        <property type="entry name" value="YALI0E31793P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09350">
        <property type="entry name" value="DJC28_CD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DnaJ homologue subfamily C member 28 conserved" evidence="2">
        <location>
            <begin position="187"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="31"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="99"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="55"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="102"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="116"/>
            <end position="133"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF09350"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ85765.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="339" mass="39476" checksum="D7150A96589B9DB7" modified="2016-11-30" version="1">MSSSTRSAYLFRLHTCYNLFPSRQSLLRKSFYSTSQSPPRNIFEPSEEDKDEKATSITKKQQLPNDKPWDGDEPVSHSVLRMIMDKYRAPLRVEGAARRNIPQPQSNFDPSSFAPQKKEKSSQEKKIERDNQLRKRKQNRITSARDAAFDYAMDRKYPTTSSQSDTDWDEWETNPTLKGIEELGQLTDAKIRSARAKGAFDNLPGRGKPIETDPMLSNPFVDRTEYFMNRIIQRNGAAPPWVIMQQEVDIEVKSLRSQMSAALKRCIHDIRDRNSYLAKPSLIREFEKLEKSYFAKEVDRVNSKLKSYNVMCPSPVRKQLLELEKELEWTLEKLELERN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N9U1</accession>
    <name>A0A1C7N9U1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">small monomeric GTPase</fullName>
            <ecNumber evidence="1">3.6.5.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">rap1b</name>
        <name evidence="6" type="ORF">A0J61_06099</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>GTP + H2O = GDP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:19669"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58189"/>
            <dbReference type="EC" id="3.6.5.2"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.5.2" evidence="1"/>
    <dbReference type="EMBL" id="LUGH01000352">
        <property type="protein sequence ID" value="OBZ85851.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N9U1"/>
    <dbReference type="STRING" id="101091.A0A1C7N9U1"/>
    <dbReference type="InParanoid" id="A0A1C7N9U1"/>
    <dbReference type="OrthoDB" id="5976022at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003925">
        <property type="term" value="F:G protein activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000182">
        <property type="entry name" value="ras-related protein Rap-1b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001806">
        <property type="entry name" value="Small_GTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020849">
        <property type="entry name" value="Small_GTPase_Ras-type"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24070">
        <property type="entry name" value="RAS, DI-RAS, AND RHEB FAMILY MEMBERS OF SMALL GTPASE SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00071">
        <property type="entry name" value="Ras"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00449">
        <property type="entry name" value="RASTRNSFRMNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00175">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00173">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00174">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51419">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51421">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51420">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00048098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OBZ85851.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="184" mass="20978" checksum="D366E27D9FCD9B1B" modified="2016-11-30" version="1">MREYKLVVLGSGGVGKSALTVQFVQSIFVEKYDPTIEDSYRKQVEVDGQQCMLEILDTAGTEQFTAMRDLYMKNGQGFILVFSIISQVTLTDLNEIREQIIRVKGSDNVPMVLVGNKCDLENERAVSREKGMSLSQQWGGKPFYETSARFKINVDEVFYDVVRQINKQNPSKDKTKKKFKCLIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N9V9</accession>
    <name>A0A1C7N9V9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">A0J61_06113</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1 8">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000353">
        <property type="protein sequence ID" value="OBZ85840.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N9V9"/>
    <dbReference type="STRING" id="101091.A0A1C7N9V9"/>
    <dbReference type="InParanoid" id="A0A1C7N9V9"/>
    <dbReference type="OrthoDB" id="1470350at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050196">
        <property type="entry name" value="Cytochrome_P450_Monoox"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24291:SF50">
        <property type="entry name" value="BIFUNCTIONAL ALBAFLAVENONE MONOOXYGENASE_TERPENE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24291">
        <property type="entry name" value="CYTOCHROME P450 FAMILY 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 7 8" id="KW-0349">Heme</keyword>
    <keyword evidence="5 7 8" id="KW-0408">Iron</keyword>
    <keyword evidence="3 7 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 8" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="4 8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" description="axial binding residue" evidence="7">
        <location>
            <position position="482"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OBZ85840.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="545" mass="62410" checksum="1277DEB46B66AF5B" modified="2016-11-30" version="1">MDQLSSFKSNLVIQNLIELYNTYALPRLTKQNQKIGISAAVAISLIYFLDRLSKPPKNLRHFPYISYYALIKSALRGESSRDFDARVVAPLLDNELNKAVYLRPLGTGWNVMIADPEIAKTVFLKTEKFPKQTPPPKMQQTIFGRFLGENSIVISNGHEWKSQRKLANPAFHRSMPVNLFGKLTLDFFDVVDQSNEHVDFTDLIQRWTLEAIGKAGFGFDFNAIKKKDNVWVTTYNVINAGFANAIYLLFPFLDQKDSFLLSPRRRKIHYHMTRFLGMLDQVILDKREAIENGNLENDYLAENEKDLLTLMIEGEMRGEGMMSNDDLRSNVCVFFLAGHDTTANTLSFAIYYLATHPEIQQKAREEAIKVLSDEPRNVLPTLEQTRELVYINQIMRETLRINGPVSRVASREAAEDFFLDEKLIPKGTPINIDINAIHHSKKLWKNPYEFDPERFAADGEGTTRKANSGMAWLPFGSGARQCIGMNFSLYEQRVFLSMLRNVSSYTLRRYTWKLPDDSIHKNGVISVGASITNTAKLDIDFTRRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NAG8</accession>
    <name>A0A1C7NAG8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="20">chitin deacetylase</fullName>
            <ecNumber evidence="20">3.5.1.41</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="24" type="primary">CDA_3</name>
        <name evidence="24" type="ORF">A0J61_05851</name>
    </gene>
    <organism evidence="24 25">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="24 25" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="24 25">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="21">
            <text>[(1-&gt;4)-N-acetyl-beta-D-glucosaminyl](n) + n H2O = chitosan + n acetate</text>
            <dbReference type="Rhea" id="RHEA:10464"/>
            <dbReference type="Rhea" id="RHEA-COMP:9593"/>
            <dbReference type="Rhea" id="RHEA-COMP:9597"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:17029"/>
            <dbReference type="ChEBI" id="CHEBI:30089"/>
            <dbReference type="ChEBI" id="CHEBI:57704"/>
            <dbReference type="EC" id="3.5.1.41"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="21">
            <dbReference type="Rhea" id="RHEA:10465"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Co(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:48828"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cell membrane</location>
            <topology evidence="3">Lipid-anchor</topology>
            <topology evidence="3">GPI-anchor</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Secreted</location>
            <location evidence="2">Cell wall</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the polysaccharide deacetylase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="24">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.5.1.41" evidence="20"/>
    <dbReference type="EMBL" id="LUGH01000328">
        <property type="protein sequence ID" value="OBZ86107.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NAG8"/>
    <dbReference type="STRING" id="101091.A0A1C7NAG8"/>
    <dbReference type="InParanoid" id="A0A1C7NAG8"/>
    <dbReference type="OrthoDB" id="407355at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098552">
        <property type="term" value="C:side of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004099">
        <property type="term" value="F:chitin deacetylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006032">
        <property type="term" value="P:chitin catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009272">
        <property type="term" value="P:fungal-type cell wall biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000272">
        <property type="term" value="P:polysaccharide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd10952">
        <property type="entry name" value="CE4_MrCDA_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.370:FF:000004">
        <property type="entry name" value="Related to Chitin deacetylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.370">
        <property type="entry name" value="Glycoside hydrolase/deacetylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011330">
        <property type="entry name" value="Glyco_hydro/deAcase_b/a-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002509">
        <property type="entry name" value="NODB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050248">
        <property type="entry name" value="Polysacc_deacetylase_ArnD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10587:SF98">
        <property type="entry name" value="CHITIN DEACETYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10587">
        <property type="entry name" value="GLYCOSYL TRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01522">
        <property type="entry name" value="Polysacc_deac_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88713">
        <property type="entry name" value="Glycoside hydrolase/deacetylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51677">
        <property type="entry name" value="NODB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="15" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="5" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6" id="KW-0134">Cell wall</keyword>
    <keyword evidence="18" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="12" id="KW-0146">Chitin degradation</keyword>
    <keyword evidence="16" id="KW-0170">Cobalt</keyword>
    <keyword evidence="14" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="8" id="KW-0336">GPI-anchor</keyword>
    <keyword evidence="11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="17" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="13" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="19" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="25" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0964">Secreted</keyword>
    <keyword evidence="10 22" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="22">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008889573" description="chitin deacetylase" evidence="22">
        <location>
            <begin position="19"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="domain" description="NodB homology" evidence="23">
        <location>
            <begin position="155"/>
            <end position="349"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010973"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022512"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022622"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="ARBA" id="ARBA00024056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="21">
        <source>
            <dbReference type="ARBA" id="ARBA00048494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="22">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="23">
        <source>
            <dbReference type="PROSITE" id="PS51677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="24">
        <source>
            <dbReference type="EMBL" id="OBZ86107.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="25">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="406" mass="45044" checksum="2995D27B642CB779" modified="2016-11-30" version="1">MQLKTLTISLAMATLATADITASNYYNSLTSQIDPKNISIPSITQTSSLDVTTECTYYSPESTLVNISTSDFPTIWETATTNGMNTSAEFTALYQSIDWTKAPNISVRTFTSSGGLDTSSYQASTDPDCWWSASTCTVPKHEGINADIYKCDEPETWGLTYDDGPNCSHNAFYDYLQQQKLKASMFYIGSNVLDWPYGAMRGVVDGHHIASHTWSHPYMTTLTNQEVLAELYYTQKAIKLVTGLTPRYWRPPYGDVDDRVRWIASQLGLTAVIWNLDTDDWEGVNSQSAYQAVEQNYQNFVEMGSNGTFANSGNIVLTHEINNLTMSLALDYLPKITSAYKQVLDVATCQNISYPYFENYEWTHTLNSTNSSTVASGSLTDKVVSSANNLVPGLSVIAGFMMAMLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NAV8</accession>
    <name>A0A1C7NAV8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_05848</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000328">
        <property type="protein sequence ID" value="OBZ86098.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NAV8"/>
    <dbReference type="InParanoid" id="A0A1C7NAV8"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ86098.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="336" mass="38711" checksum="26D4D61EC8384AA4" modified="2016-11-30" version="1">MSISKNRASQYSRLIRLTPNVKTLRAKANDESLFQTVLLEMQKGHWKQLYRILEENLSNNWKVSLCHDYYTLISTIQDKLVFVMLNIPSDPNLLDQPSCFRLPSRITKQTRFNAAETVLCSSRGKTEIKVLEDALALCPNAVCVVLSHTSLDWYEDGTRNFEPNTTVKGLSVTLGEYTEGSLDYICHKFPDVEELVIGVSIDSESDFCISEDIAVQLADFAYRTNKCYVSLEVVEGHEQWLPAFISHEWAGELNIFLQEHCFCFRHDKSKPRLSTLHIEGDIEYLEDLSESVEAYFRQLDELDINQGGRSCDRLLEYCPQLRRTRNGYCYVRSTMI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NB22</accession>
    <name>A0A1C7NB22_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Protein CWC15 A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">cwc15-a</name>
        <name evidence="6" type="ORF">A0J61_05625</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Involved in pre-mRNA splicing.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the CWC15 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000309">
        <property type="protein sequence ID" value="OBZ86322.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NB22"/>
    <dbReference type="FunCoup" id="A0A1C7NB22">
        <property type="interactions" value="464"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NB22"/>
    <dbReference type="InParanoid" id="A0A1C7NB22"/>
    <dbReference type="OrthoDB" id="30179at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071013">
        <property type="term" value="C:catalytic step 2 spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071014">
        <property type="term" value="C:post-mRNA release spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000974">
        <property type="term" value="C:Prp19 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045292">
        <property type="term" value="P:mRNA cis splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006973">
        <property type="entry name" value="Cwf_Cwc_15"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12718">
        <property type="entry name" value="CELL CYCLE CONTROL PROTEIN CWF15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12718:SF2">
        <property type="entry name" value="SPLICEOSOME-ASSOCIATED PROTEIN CWC15 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04889">
        <property type="entry name" value="Cwf_Cwc_15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="4" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="65"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="79"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="120"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="141"/>
            <end position="171"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006644"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OBZ86322.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="232" mass="27276" checksum="3E54997C42601206" modified="2016-11-30" version="1">MTTAARPTFDPARGNDNKAPSFQYSARDLASHTKLKFRQPGQGTIDEIGDRQQLLEELRRAEQEYYEEKEGKASTMRFIKQEEEQDDKEKQRLKEEAERLAKLDKDDSDQESDSGGSDSSDSEDEEDDDDDDAAELMAELQRIRKERAEEKERQEREALEEAEAEKEREAMEGNPLLNIGDQKRDFSVKRRWDDDVIFKNQARGVDDKPKKRFVNDMIRSDFHRRFLHKYIH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NB65</accession>
    <name>A0A1C7NB65_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Transposable element Tc1 transposase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">tc1a_6</name>
        <name evidence="1" type="ORF">A0J61_05701</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000316">
        <property type="protein sequence ID" value="OBZ86240.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NB65"/>
    <dbReference type="STRING" id="101091.A0A1C7NB65"/>
    <dbReference type="InParanoid" id="A0A1C7NB65"/>
    <dbReference type="OrthoDB" id="2283219at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="199"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ86240.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="199" mass="23273" checksum="BD28498342BAF3AC" modified="2016-11-30" version="1" fragment="single">LSKQRKKNCLNLAKDRIGWLREEWAHVTWSDESRYTTEGPDDGIRVFRQAGERHKDKFMIPTIKWEKDSVMVWECFFGAGIESLVFSDGSMDQVKFIDALSEKSQPWFLELATSHTGRVACEFDCWPAQGSYLSLIEHMWSTLELRIKERRYEVYNTQKSKRLLQDEWNRIGDDDLIARLVNSMKDRCQAVIDLKGGTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NC31</accession>
    <name>A0A1C7NC31_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_05384</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000289">
        <property type="protein sequence ID" value="OBZ86558.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NC31"/>
    <dbReference type="InParanoid" id="A0A1C7NC31"/>
    <dbReference type="OrthoDB" id="2297888at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="144"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="144"/>
            <end position="169"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ86558.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="547" mass="61449" checksum="25A28BB2F688DB48" modified="2016-11-30" version="1">MSCFRDHTFVVCNGKYLDFSASPYASNFLASPDANDIPFLFTDRHVHFLKSGFYDVRGLQTKTKTEYPLRTLLMEAISDSVNQFIQPKNTLHMACYESALTNYITNLSVIWGDNKMINILLDKLLLVLLRIHLAPTRERKHQEFIKSMKNASKERKDKAAKGSKTEADHPTNWFPLLHQSRRRLIVRGYEAKMGSSSPKKNPRLLLPRGNNLLSLMSPKVLSVQKKIPAIQHPSIASAEAGPSMLQTGRMEIDIPTQPYEGKGKAPMNPQSDPKPATFQPLMTGETHTIPPAVPEDYASMDENDVVEEEDALKDADDDAPRNRLNGLKGFIKSLLLRGEDLPNEEDLEDLRSDLNEKETEKIPAIQHPSTASAEAGPSMLHTSRMEIDIPTRPYEGKGKVPMNPQSDPNSVTFQPPMTGEIHTIPLAVPEDYASMDENGVVEEEDALKDVDDGAPRNRLNGLKGFIKSLLLRDEDLHNEQDLTGLRSDLNEKETKLKILHPFKEELLSYWLQATFCKILANDLLRCAGYAKFCRKICPMPTATQSSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NCD1</accession>
    <name>A0A1C7NCD1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_05166</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000272">
        <property type="protein sequence ID" value="OBZ86777.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NCD1"/>
    <dbReference type="InParanoid" id="A0A1C7NCD1"/>
    <dbReference type="OrthoDB" id="2225742at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ86777.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="113" mass="13044" checksum="E58CD4081B52CAF1" modified="2016-11-30" version="1">MLNRIQIRCASVLASLPPTPHTTHSLHHTQPYIVTPASQPITARSNNAFHPNYIPKNTKERLALDELHQVLDNSKAMYKILESRYLDKKTAEDSSLKELLEEQYRLIQLLKKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NDA5</accession>
    <name>A0A1C7NDA5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_04858</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000247">
        <property type="protein sequence ID" value="OBZ87093.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NDA5"/>
    <dbReference type="InParanoid" id="A0A1C7NDA5"/>
    <dbReference type="OrthoDB" id="2220023at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="11"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ87093.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="187" mass="21226" checksum="197A4C790CB3428D" modified="2016-11-30" version="1">MYFALPKNTERQTPSSSLKLTGAKMSNLSPEPETMCEDRISEIIHNIDDHWGSPPILTPNTLTHILNNQWVASDYHSTEENMKKQPKGHSLTKTPGTVMLTGAPSIAKSTNQNDRDDKMLPILIQEVCKTIESISMDSKHSIANDIKNDPIIQRFIMSKKEEETSQEVVLRHLTQILQNHNKNQQQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NDI6</accession>
    <name>A0A1C7NDI6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Splicing factor 3B subunit 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">sf3b3</name>
        <name evidence="10" type="ORF">A0J61_05334</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the RSE1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000285">
        <property type="protein sequence ID" value="OBZ86616.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NDI6"/>
    <dbReference type="FunCoup" id="A0A1C7NDI6">
        <property type="interactions" value="1395"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NDI6"/>
    <dbReference type="InParanoid" id="A0A1C7NDI6"/>
    <dbReference type="OrthoDB" id="436637at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005681">
        <property type="term" value="C:spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008380">
        <property type="term" value="P:RNA splicing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.150.910:FF:000002">
        <property type="entry name" value="Splicing factor 3B subunit 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.10:FF:000031">
        <property type="entry name" value="Splicing factor 3b subunit 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.10:FF:000640">
        <property type="entry name" value="Splicing factor 3B subunit 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.910">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018846">
        <property type="entry name" value="Beta-prop_RSE1/DDB1/CPSF1_1st"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058543">
        <property type="entry name" value="Beta-prop_RSE1/DDB1/CPSF1_2nd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050358">
        <property type="entry name" value="RSE1/DDB1/CFT1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004871">
        <property type="entry name" value="RSE1/DDB1/CPSF1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10644">
        <property type="entry name" value="DNA REPAIR/RNA PROCESSING CPSF FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10433">
        <property type="entry name" value="Beta-prop_RSE1_1st"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23726">
        <property type="entry name" value="Beta-prop_RSE1_2nd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03178">
        <property type="entry name" value="CPSF_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="4" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0747">Spliceosome</keyword>
    <feature type="domain" description="RSE1/DDB1/CPSF1 first beta-propeller" evidence="8">
        <location>
            <begin position="13"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="domain" description="RSE1/DDB1/CPSF1 second beta-propeller" evidence="9">
        <location>
            <begin position="454"/>
            <end position="770"/>
        </location>
    </feature>
    <feature type="domain" description="RSE1/DDB1/CPSF1 C-terminal" evidence="7">
        <location>
            <begin position="852"/>
            <end position="1180"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00038266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF03178"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF10433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF23726"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OBZ86616.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="1214" mass="135458" checksum="9839DE1BDDB25261" modified="2016-11-30" version="1">MFLYNLTINPTTAINQAIHGNFSGTRQQEIVVAKQTRLELLRPDTTSGKVHTILSHECFGLIRTIAPFRLTGGSKDYIVVGSDSGRIVILEYNPTKNTFDKVHQETYGKTGCRRIVPGQYLAVDPKGRAVMIGAVEKQKLVYILNRDSAANLTISSPLEAHKSHTIHHHMVAIDVGFENPMFACLEVDYTDADTDPTGEAANEAEKTLTYYELDLGLNHVVRKWSEAVDRKANLLIPVPGGNDGPSGVLVCSENFIAYKHPELEELRIPIPRRAQPLEDPTRGIIIVTYAVHRMRVDKKTQFFFLLQSEEGDLYKVTMDHDQGAVSGLTIKYFDTIPIATSLCILKSGFLFVANEFGNHHHYFFESLGDDDDDPEISSADYMEAEAEQEERPLVYFKPRPLKNLSLVDELNSMAPLMDSKVLNLADEETPRIYSICGKGSQSTFRILNQGVEASELAVSELPGNPSAVWTTKLKQEDAYHAYIVVSFANATLVLSIGETVEEVQDTGFLTNEPTLTVQQMGDDALIQVHPRGIRHILSSGRVNEWKAPSGQKIVEAASNSRQIAIALSNGEIVYFELDNMGQLNEHQERKQMSSAISALSLGDVPEGRQRSRFLAVGCEDQTVRMLSLDPDACLEAISMQALQGVPSSLCILEMMDTGIEQGHGTTYLNIGMSNGLFLRTALDTVTGQLSDTRTRFLGPKSVKLFKISIQGLPAVLALSTKPWVSYTFQNRLYLMPLSYEMLEYGSAFMSEQCPEGVVAIAGNTLRIFTVEKLGNIFNQVAIPLKYTPRQFALHAPSRTFVVIESDHATYAPEAKRKGIEEKEQEGFEIDPEITELDPVQFGHVRHTSGKWASCIRLIEPFGGTTLQCLDLEENEAAFSVAMVQFRQNPHATDPQEQFIVVGTGQNVTLQPRSCTAGYLRVYRIVQAQDGSLCLTFIHRTPLEETPHALLAFQGRLLVGAGKSLRIYDIGKKKMLRKCETKTLPNCIVSLHTQGHRIIATDIQESMHYVIYKHADNRLVIFADDTVPRWMTASTMVDYETVAGGDKFGNFFVNRLPASVSREIDEDTTGNRIYHEKGYLQGAPNKVESLAEYFSGDIITSIHRTALLSGGREVLLTTSILGSISIYVPFISKEDVEFFQMLEMHMRAEAPPLAGREHLLYRSYYIPVKNVIDGDLCEQFNSLPPEKRRMIAEELDRSVTDVQKKIEDIRMRSGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NDY0</accession>
    <name>A0A1C7NDY0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Low molecular weight phosphotyrosine protein phosphatase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">LTP1</name>
        <name evidence="9" type="ORF">A0J61_04637</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6 11">
            <text>O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:10684"/>
            <dbReference type="Rhea" id="RHEA-COMP:10136"/>
            <dbReference type="Rhea" id="RHEA-COMP:20101"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:46858"/>
            <dbReference type="ChEBI" id="CHEBI:61978"/>
            <dbReference type="EC" id="3.1.3.48"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the low molecular weight phosphotyrosine protein phosphatase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000231">
        <property type="protein sequence ID" value="OBZ87307.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NDY0"/>
    <dbReference type="FunCoup" id="A0A1C7NDY0">
        <property type="interactions" value="279"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NDY0"/>
    <dbReference type="InParanoid" id="A0A1C7NDY0"/>
    <dbReference type="OrthoDB" id="3388at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003993">
        <property type="term" value="F:acid phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004726">
        <property type="term" value="F:non-membrane spanning protein tyrosine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd16343">
        <property type="entry name" value="LMWPTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.2300:FF:000105">
        <property type="entry name" value="Low molecular weight phosphotyrosine protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050438">
        <property type="entry name" value="LMW_PTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023485">
        <property type="entry name" value="Ptyr_pPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036196">
        <property type="entry name" value="Ptyr_pPase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002115">
        <property type="entry name" value="Tyr_Pase_low_mol_wt_mml"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017867">
        <property type="entry name" value="Tyr_phospatase_low_mol_wt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11717:SF7">
        <property type="entry name" value="LOW MOLECULAR WEIGHT PHOSPHOTYROSINE PROTEIN PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11717">
        <property type="entry name" value="LOW MOLECULAR WEIGHT PROTEIN TYROSINE PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01451">
        <property type="entry name" value="LMWPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00719">
        <property type="entry name" value="LMWPTPASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00720">
        <property type="entry name" value="MAMMALPTPASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00226">
        <property type="entry name" value="LMWPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52788">
        <property type="entry name" value="Phosphotyrosine protein phosphatases I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0904">Protein phosphatase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Phosphotyrosine protein phosphatase I" evidence="8">
        <location>
            <begin position="6"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="7">
        <location>
            <position position="12"/>
        </location>
    </feature>
    <feature type="active site" evidence="7">
        <location>
            <position position="18"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="7">
        <location>
            <position position="128"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00051722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR617867-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OBZ87307.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="158" mass="17571" checksum="185B257183A1AFA5" modified="2016-11-30" version="1">MSKDSVSVLFVCLGNICRSPMAEAVFAHTVKQNNLQDRFSKIDSAGTASYHVGSSPDSRSASTCKAHGVPVKHKARKVTKQDFEDFDYVLCMDESNLSDLKRLQPKGSKAVLKLFGEYDPEGELIIEDPYYGGNDGFEHNFRQVTRASEGLLRALEFM</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NDZ8</accession>
    <name>A0A1C7NDZ8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">WD40 repeat-containing protein SMU1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">HET-E1</name>
        <name evidence="11" type="ORF">A0J61_04775</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus speckle</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the WD repeat SMU1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000241">
        <property type="protein sequence ID" value="OBZ87170.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NDZ8"/>
    <dbReference type="STRING" id="101091.A0A1C7NDZ8"/>
    <dbReference type="InParanoid" id="A0A1C7NDZ8"/>
    <dbReference type="OrthoDB" id="674604at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016607">
        <property type="term" value="C:nuclear speck"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006595">
        <property type="entry name" value="CTLH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006594">
        <property type="entry name" value="LisH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045184">
        <property type="entry name" value="SMU1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054080">
        <property type="entry name" value="TPR1-like_2nd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22848">
        <property type="entry name" value="WD40 REPEAT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21889">
        <property type="entry name" value="TPR1-like_2nd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00668">
        <property type="entry name" value="CTLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50897">
        <property type="entry name" value="CTLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50896">
        <property type="entry name" value="LISH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="6"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="5" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 8" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="CTLH" evidence="10">
        <location>
            <begin position="99"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="8">
        <location>
            <begin position="277"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="8">
        <location>
            <begin position="320"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="8">
        <location>
            <begin position="360"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="8">
        <location>
            <begin position="402"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="8">
        <location>
            <begin position="444"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="8">
        <location>
            <begin position="503"/>
            <end position="529"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="8">
        <location>
            <begin position="530"/>
            <end position="561"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00025801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00026184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50897"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="OBZ87170.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="571" mass="64779" checksum="7873FE57678312B5" modified="2016-11-30" version="1">MNTDNDIEPEDATLLPLGNSVSHSTEAKQKRKLATLNQHVGMQASHIQPTDDIFNSNDPQIKQDIITMMMQYLQEEGYHASQSVLYDEANVKWKEREERTLEIKRLKKAILDGEWQEVEKLCTKPLVKNHRSFLYSVYKQQYLEYLERREIQKAFTFLNKRLKPLEHFQTKPNEFRDMCYLLTAKSIHEAPSFKHWEGIMASRENLVDQLQNMLEFESADRTGHRHIPPDRLLTLLRQAVAYQIEFSRYHPKIAPTVSTLLDDYSSFVIPNALCASLEGHTGNVKCISFLGAEGERIVSGSSDNTLRIWDTETAECLDVLQGHRSRIWDVSTTQELIASASGDATVKIWNARQATNISTLTGHAGDVYSVQYHPNETHVVTGGYDKTVRLFDVNTGTIVKTFPGHQLAVTKTIFNPLGNLVISGSKDNTIKFWDIVSGLCIRTISSHLGEVTSVEMNASGTQLLSSSKDNSNRLWDVRMVRPIRKLKGHQNTSKNFVRAHFANNNLIMGGSEDGIVYIWDQETGEVLQRLRGHSGVVYEAAWHAKQGLLASCSDDQTVKVWWYDDSVPLDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NE24</accession>
    <name>A0A1C7NE24_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_04764</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000240">
        <property type="protein sequence ID" value="OBZ87190.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NE24"/>
    <dbReference type="STRING" id="101091.A0A1C7NE24"/>
    <dbReference type="InParanoid" id="A0A1C7NE24"/>
    <dbReference type="OrthoDB" id="2259253at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="17"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="19"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="38"/>
            <end position="48"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ87190.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="183" mass="20336" checksum="CC154918AC587E39" modified="2016-11-30" version="1">MGASICSAILLWHEKKQRHIGEHHSEESKKGETDSFETDNQTVTNTQDALDSIPKQTIPISNDEPDRFVCHHSPPSTVNLSYSPLIHEPNSPYEGLQRPVSTIIAPYTPSPLIMSPQAPLQQPYYSSDNLPNVAHVHGNSAYYSSPHATANLPYQSLHSPYSSSDYSNTNMSYPFNPSHYASQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NE62</accession>
    <name>A0A1C7NE62_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Neprilysin-1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">nep-1_2</name>
        <name evidence="9" type="ORF">A0J61_04720</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000237">
        <property type="protein sequence ID" value="OBZ87230.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NE62"/>
    <dbReference type="STRING" id="101091.A0A1C7NE62"/>
    <dbReference type="InParanoid" id="A0A1C7NE62"/>
    <dbReference type="OrthoDB" id="6475849at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016485">
        <property type="term" value="P:protein processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd08662">
        <property type="entry name" value="M13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.390.10">
        <property type="entry name" value="Collagenase (Catalytic Domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1380.10">
        <property type="entry name" value="Neutral endopeptidase , domain2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024079">
        <property type="entry name" value="MetalloPept_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000718">
        <property type="entry name" value="Peptidase_M13"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018497">
        <property type="entry name" value="Peptidase_M13_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042089">
        <property type="entry name" value="Peptidase_M13_dom_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008753">
        <property type="entry name" value="Peptidase_M13_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11733:SF240">
        <property type="entry name" value="GH14155P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11733">
        <property type="entry name" value="ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01431">
        <property type="entry name" value="Peptidase_M13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05649">
        <property type="entry name" value="Peptidase_M13_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00786">
        <property type="entry name" value="NEPRILYSIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55486">
        <property type="entry name" value="Metalloproteases ('zincins'), catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51885">
        <property type="entry name" value="NEPRILYSIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Peptidase M13 N-terminal" evidence="8">
        <location>
            <begin position="40"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M13 C-terminal" evidence="7">
        <location>
            <begin position="532"/>
            <end position="742"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01431"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF05649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OBZ87230.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="744" mass="84328" checksum="9D70D271764B8875" modified="2016-11-30" version="1">MPPIDLFTRAPVHSNNVCNTTACIAASEYILSRVNLTIDPCSDFYQYTCGSWINSPAVKEEYNQGIVTREVTTFTVQNKRRQAQILEGTYEDFKQQIKPNATGFHLEDQAELDKSNFEFYKSYYNVCKDTNLYHVNRFTPIFEDIMTIQKDIVPLNATAGQYGRAMAFFIQQSLSILPFEMDITPSFLDRDKYEVLIGGSSAFENYTYDREVIVSRLNQVIGQPEADSINAQTTIEASQRSGLELWSNNTILAAVDNHERIVSFIRDIYNSSASDFKFEIEDLISGPAISFDAVQQALSKVDISVLLTTLSEGLDSSAVASLHFRTAPFFLGDINDMLSTESEKSIQDFFIVQYIVDKYEYLAPSLFPELLNNTILQQQNFTVSNTTVALMKLQCSEDTNAHFVYGLSRYYGLEGFGGENDRQKTLKFIETIRESLLARISNNTWLDDQTKQAAINKMKLTKTDSAYSIHDPDWRDPASIKQYYGNQTIDTRSYYHAKKSALLETSKRKWKNISAEPTSTIWDMLEYPGMVNAAYLPSSNSIGVLLGILRKPMYDTDFPEYLNFGNLGSIIGHEFVHGLDNLGSRFNGTGHLENWWTPQAAKEYEERQQCFIEEYSKISITDEEGNEVFIDGNLTLGENIADAGGLNAAVDAYKLYVRNERQGQPEPSLPGLEHLTPEQMLYISFSLFHCESVPPSQARVYETDVHAPFFARTNPVVQNNADFATTFNCPADSPMNKKEKCYLW</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NEA0</accession>
    <name>A0A1C7NEA0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Tankyrase-1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">Tnks</name>
        <name evidence="5" type="ORF">A0J61_04501</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000222">
        <property type="protein sequence ID" value="OBZ87443.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NEA0"/>
    <dbReference type="STRING" id="101091.A0A1C7NEA0"/>
    <dbReference type="InParanoid" id="A0A1C7NEA0"/>
    <dbReference type="OrthoDB" id="194358at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004842">
        <property type="term" value="F:ubiquitin-protein transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0085020">
        <property type="term" value="P:protein K6-linked ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24171">
        <property type="entry name" value="ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 39-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24171:SF8">
        <property type="entry name" value="BRCA1-ASSOCIATED RING DOMAIN PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00023">
        <property type="entry name" value="Ank"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01415">
        <property type="entry name" value="ANKYRIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="83"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="116"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="149"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="215"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="248"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="282"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="14"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="26"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="43"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="324"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OBZ87443.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="324" mass="36161" checksum="2A8EDA913EEDDA1A" modified="2016-11-30" version="1" fragment="single">MFEYQQSTKKRYPTQKQNASLHTLDNEEEEEDDNMDQDYYRIQLKKKKRRLRAMTQSSSPEPQPSLKKGRKKALLNPNRKDKAGRTKLFFATTAGHLDKVKELIESGADVNFKDNAGWTPLHEAALKGQYEIGKHLIACGAEINVRGFGLDTPLHDACSSNSPECVQLLVDAGADVFALNEAEKRPIDLCTDEACQRILQAKMNELERLIARDQQGRSSLHRACISNRLQKAQSLIEQGADVNAKDNQEATPLHLACASGHLNIVKLLIDQGAIVNILGTDRDDTPLHQASHHGHLETVKYLISSAGADVNMKDKSGKNPYHYD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NER7</accession>
    <name>A0A1C7NER7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">3'-5' exonuclease</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Werner Syndrome-like exonuclease</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="primary">WRN</name>
        <name evidence="11" type="ORF">A0J61_04500</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000221">
        <property type="protein sequence ID" value="OBZ87450.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NER7"/>
    <dbReference type="InParanoid" id="A0A1C7NER7"/>
    <dbReference type="OrthoDB" id="2278185at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008408">
        <property type="term" value="F:3'-5' exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006139">
        <property type="term" value="P:nucleobase-containing compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06141">
        <property type="entry name" value="WRN_exo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002562">
        <property type="entry name" value="3'-5'_exonuclease_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051132">
        <property type="entry name" value="3-5_Exonuclease_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13620:SF109">
        <property type="entry name" value="3'-5' EXONUCLEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13620">
        <property type="entry name" value="3-5 EXONUCLEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01612">
        <property type="entry name" value="DNA_pol_A_exo1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="11" id="KW-0347">Helicase</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0540">Nuclease</keyword>
    <keyword evidence="11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="3'-5' exonuclease" evidence="10">
        <location>
            <begin position="135"/>
            <end position="292"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00040531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00042761"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF01612"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="OBZ87450.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="391" mass="44185" checksum="3D3164A645366FF1" modified="2016-11-30" version="1">MQYAXFVPSGTYVRTLYTAIIQTLRPKMDKHMMLLDGKILKGDHYFKLPKHMTKINEVSVFTALYTATNEYEEIVQQMSVPSKALSYLRFSFEKMCEDYSLYGHEMPIAFFTDNLPETVEAVYVARDYDAINKHFRQLLEGLKNDEDKTVGFDAEWAPFSAGDKVDVVQVVYENKVLMIHLDQSWQELPPYFQAFLRDATIRKLGRQVGGDLGRINRGCHLMCRGALELGSFYSARKCIPNGQMSLTEIAFKVLGMKIKKDERLSDWSISPLSAQQIEHAAIDAWASMAINTAVRSKPEIGTRISSRNCLPGVCVAXKPRQAKSVVAHGKFCSDITNQGVVMVSILRVKLSRFYFSLNSCTITENPRSLNSFGAVRFELSIPMKDLVAVAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NF63</accession>
    <name>A0A1C7NF63_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">GST N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_04192</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000199">
        <property type="protein sequence ID" value="OBZ87752.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NF63"/>
    <dbReference type="STRING" id="101091.A0A1C7NF63"/>
    <dbReference type="InParanoid" id="A0A1C7NF63"/>
    <dbReference type="OrthoDB" id="412788at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004364">
        <property type="term" value="F:glutathione transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00570">
        <property type="entry name" value="GST_N_family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1050.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036282">
        <property type="entry name" value="Glutathione-S-Trfase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004045">
        <property type="entry name" value="Glutathione_S-Trfase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004046">
        <property type="entry name" value="GST_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044617">
        <property type="entry name" value="TCHQD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45374">
        <property type="entry name" value="GLUTATHIONE S-TRANSFERASE TCHQD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45374:SF1">
        <property type="entry name" value="GLUTATHIONE S-TRANSFERASE TCHQD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14497">
        <property type="entry name" value="GST_C_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13409">
        <property type="entry name" value="GST_N_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47616">
        <property type="entry name" value="GST C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50404">
        <property type="entry name" value="GST_NTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GST N-terminal" evidence="1">
        <location>
            <begin position="5"/>
            <end position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ87752.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="249" mass="28599" checksum="56F9933C2D7DE1D3" modified="2016-11-30" version="1">MTRVKNNILYYSPGSTFSNVGLLLIHEKGLEDQFEFKAIKLGQDNISPWYIQLNPKGQVPTMIYQSNVVSDSLSIARFLDPCVQPPSFECDNQKVMDFVKPWRQLRLLPLFAGKKDLDQDMSTMESTLAKARAQQLAHAKAHPDLAESYEIRLGVHNERAEMLLEYDQFLFHRHMLNRLLDEAEKALDTNDGHLLSIKQHTLADIYVMANLYCAHQKISSDILVNRSKLKEYYQQQMARPSVAKAFLLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NFX5</accession>
    <name>A0A1C7NFX5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_04493</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000221">
        <property type="protein sequence ID" value="OBZ87456.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NFX5"/>
    <dbReference type="InParanoid" id="A0A1C7NFX5"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="40"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="40"/>
            <end position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ87456.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="77" mass="9033" checksum="8680091F2E296499" modified="2016-11-30" version="1">MLRMQSAWPHQIFCKQKQDVLRDKVEDSLLIVEYEKLEQNRDVNERKDRSTDGLPKLYTREGPEASRWAPNSAAANM</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NGD9</accession>
    <name>A0A1C7NGD9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_03901</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000179">
        <property type="protein sequence ID" value="OBZ88050.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NGD9"/>
    <dbReference type="InParanoid" id="A0A1C7NGD9"/>
    <dbReference type="OrthoDB" id="2210039at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ88050.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="132" mass="15439" checksum="A2B512C9A87CE61D" modified="2016-11-30" version="1">MNSETQQEIKAHKNNLDKYYEYRIYDRNIGDRIYDSPCSEYAPCPIVVMSRHQGFLWNDELFVSAYRRKAGYECHKSTSLKCKEDRLKSTCSIKSMQCSPVRQDRLDEQDSSDSPPDVIEINLTEADCDVWP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NGZ2</accession>
    <name>A0A1C7NGZ2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Trehalase</fullName>
            <ecNumber evidence="5">3.2.1.28</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Alpha-trehalose glucohydrolase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">treB</name>
        <name evidence="8" type="ORF">A0J61_03558</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 5">
            <text>alpha,alpha-trehalose + H2O = alpha-D-glucose + beta-D-glucose</text>
            <dbReference type="Rhea" id="RHEA:32675"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15903"/>
            <dbReference type="ChEBI" id="CHEBI:16551"/>
            <dbReference type="ChEBI" id="CHEBI:17925"/>
            <dbReference type="EC" id="3.2.1.28"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the glycosyl hydrolase 37 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.28" evidence="5"/>
    <dbReference type="EMBL" id="LUGH01000155">
        <property type="protein sequence ID" value="OBZ88401.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NGZ2"/>
    <dbReference type="FunCoup" id="A0A1C7NGZ2">
        <property type="interactions" value="51"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NGZ2"/>
    <dbReference type="InParanoid" id="A0A1C7NGZ2"/>
    <dbReference type="OrthoDB" id="3542292at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004555">
        <property type="term" value="F:alpha,alpha-trehalase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005993">
        <property type="term" value="P:trehalose catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008928">
        <property type="entry name" value="6-hairpin_glycosidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012341">
        <property type="entry name" value="6hp_glycosidase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001661">
        <property type="entry name" value="Glyco_hydro_37"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018232">
        <property type="entry name" value="Glyco_hydro_37_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011120">
        <property type="entry name" value="Trehalase_Ca-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23403:SF6">
        <property type="entry name" value="CYTOSOLIC NEUTRAL TREHALASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23403">
        <property type="entry name" value="TREHALASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01204">
        <property type="entry name" value="Trehalase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07492">
        <property type="entry name" value="Trehalase_Ca-bi"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00744">
        <property type="entry name" value="GLHYDRLASE37"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48208">
        <property type="entry name" value="Six-hairpin glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00927">
        <property type="entry name" value="TREHALASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00928">
        <property type="entry name" value="TREHALASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="3 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Neutral trehalase Ca2+ binding" evidence="7">
        <location>
            <begin position="78"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="37"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005615"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU361180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF07492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OBZ88401.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="763" mass="88121" checksum="0718A3A411894017" modified="2016-11-30" version="1">MSTQRAFDADSSHDVHAPASTYYTTGDNARHRTRTYTRSHDMQATGVGLEGARKRRASHDDKNKARRFLIDVEETQRKILEQEDTDGDFQITINDLGPKTMSLGTADSGGYRKIDIRGTYMLSNLLQELALANDYGRKHIVLDEARLNENPVDRLSRMIKFNFWDGLTRRIDADSLEVICPDPKNRSSNKNPRIYVPYDDKEAYEFYKKAGEVRKHMNLEVEYLPKEITAEFTKSINDRPGLLTLAMKKVKDEQGRDTFIGEPFVVPGGRFNEMYGWDSYFTSLGLIEDGRLDLVRSMVENFAYQIKHYGKILNANRSYYLSRSQPPFLTDMVLKVYEKLHPDDKEENKAWLRRVMKSCIKEYWDVWMSEPRLDKKTMLSRYRPDGIGIPPETEASHFIHIIEPFAAKHNVSIDEFNQKYNDGEIKEPELDEYFLHDRAVRESGHDTTYRFEKVCANLATIDLNSLLYKYEIDIADVIRDHLDDDLEDFNGVKQNAEDWLERAKLRRERIDKYLWNEKESLYFDYDTVKEEQTTYESVTGFWALWAGCASQHQAQEMVKHSLSKFEVMGGLVSGTEESRGTISLERPNRQWDFPFGWAPHQILAWIGLDKYGMRDTAARLAYRWLFTITKGFVDFNGVVPEKFDVVSLSHKVEVEYGNVGTDFKCVPREGFGWMNASFQVGLSYLSTQMRRALGACTLPDLLFEKAMIREHRMLGMTPEEEEAVSLRRRTSTMAARAITRNGSISAAVTRISLSDGASNSPHF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NHE2</accession>
    <name>A0A1C7NHE2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">High-affinity methionine permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">MUP1_1</name>
        <name evidence="6" type="ORF">A0J61_03401</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000145">
        <property type="protein sequence ID" value="OBZ88543.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NHE2"/>
    <dbReference type="STRING" id="101091.A0A1C7NHE2"/>
    <dbReference type="InParanoid" id="A0A1C7NHE2"/>
    <dbReference type="OrthoDB" id="10062876at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015179">
        <property type="term" value="F:L-amino acid transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1740.10">
        <property type="entry name" value="Amino acid/polyamine transporter I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002293">
        <property type="entry name" value="AA/rel_permease1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050598">
        <property type="entry name" value="AminoAcid_Transporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11785">
        <property type="entry name" value="AMINO ACID TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11785:SF353">
        <property type="entry name" value="METHIONINE TRANSPORTER (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13520">
        <property type="entry name" value="AA_permease_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006060">
        <property type="entry name" value="AA_transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="41"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="75"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="119"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="164"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="193"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="226"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="270"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="322"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="372"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="395"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="432"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="461"/>
            <end position="483"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OBZ88543.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="524" mass="58213" checksum="6053F02A36C0CFC7" modified="2016-11-30" version="1">MPSTQDEQLEPMLPHDDLTDQIEHMEPLAVGDQRLERKIGWIQGAAMNVSYMIGAGIFVGPALTLQLVGSGGMNLLIWFFGALVALSGTYTFMELGTMLPRSGGEIGYLDYCYRKPKYLLAYLFTYWSLMNRSSGVASQGVVFGRYLNYALFGPSYKSEWLERAWSFLCATILTFVNIYSTKTTMKMISFLTVIKIFVLVLAIFVGALVLLRVIPSDVDAGLNLSFYGTSTTLGPYASALYYVLNSYSGWHNLNYILDEVKDPIKNLPKASAAAVLSTATLYILTNAAYLVVLPLETMKNSQLVVAAAFFSRSLGDNFASNILPIFIGLSAFGCGAALNFSGGRIIMEVARQGLLPYGHIFGRVNPKVSSPVNAYLLQYALSVLFLVGIPPGSIYQFVVALTAYPVYIFYFLMALAVLILRKREPNNKRPIVAPLVCVYVFWAFTAYALVFVFIPVENNQYPYWLPYTTAILFMFACAGLWYYQIVIRDTPGKSYNESIRNQGHAAIEQEIYGQYASVPTQDVT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NHT0</accession>
    <name>A0A1C7NHT0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Cut9-interacting protein scn1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">scn1</name>
        <name evidence="1" type="ORF">A0J61_03279</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000138">
        <property type="protein sequence ID" value="OBZ88667.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NHT0"/>
    <dbReference type="FunCoup" id="A0A1C7NHT0">
        <property type="interactions" value="16"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NHT0"/>
    <dbReference type="InParanoid" id="A0A1C7NHT0"/>
    <dbReference type="OrthoDB" id="413993at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016788">
        <property type="term" value="F:hydrolase activity, acting on ester bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.140">
        <property type="entry name" value="Metal-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053044">
        <property type="entry name" value="Metallo-hydrolase/TatD-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001130">
        <property type="entry name" value="TatD-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47345">
        <property type="entry name" value="CUT9-INTERACTING PROTEIN SCN1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47345:SF1">
        <property type="entry name" value="CUT9-INTERACTING PROTEIN SCN1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01026">
        <property type="entry name" value="TatD_DNase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="Metallo-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ88667.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="351" mass="40113" checksum="A28C09F3975DF420" modified="2016-11-30" version="1">MCQEQAIFKHDVPMTKEQFDLKLFKELCDAHCHPHDDIDNLAMIPKLQTGHITIMGVRQDDWERVSQTTKECNKEMDNKCIPCFVCLFVKGIHPWFSHFVSTPEKSGLTSKEYYASILQSSDSKQLEEMIQALPEPSSYDTWYHRLRQRLEQHPEALVGEVGVDRSARLLPGGAIDWHGKKPTQVQTSIEHQLAILDIQCQLARELNRGVSLHCVQGQGHLFDHLKKQSTQFSGRKLRQLKEKPNMLRVCLHSFGGSPATVTQFIELKGFEIYVSFSVAINAQHLPPHKMQALICSVPEDRLLIESDLNTPKGIDVCMIDIVKIVAEARNLTIAQVIEITNRNWKRFVNLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NHZ5</accession>
    <name>A0A1C7NHZ5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">3-oxoacyl-[acyl-carrier-protein] reductase FabG</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">fabG_3</name>
        <name evidence="3" type="ORF">A0J61_03184</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000133">
        <property type="protein sequence ID" value="OBZ88763.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NHZ5"/>
    <dbReference type="STRING" id="101091.A0A1C7NHZ5"/>
    <dbReference type="InParanoid" id="A0A1C7NHZ5"/>
    <dbReference type="OrthoDB" id="417891at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05233">
        <property type="entry name" value="SDR_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000084">
        <property type="entry name" value="Short-chain dehydrogenase reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF005559">
        <property type="entry name" value="PRK07231.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43180">
        <property type="entry name" value="3-OXOACYL-(ACYL-CARRIER-PROTEIN) REDUCTASE (AFU_ORTHOLOGUE AFUA_6G11210)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43180:SF66">
        <property type="entry name" value="SHORT-CHAIN DEHYDROGENASE_REDUCTASE FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13561">
        <property type="entry name" value="adh_short_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ88763.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="277" mass="29569" checksum="F32E2CA8DB2A022F" modified="2016-11-30" version="1">MTTGTRLSGKVAIVTGAAGGIGFETAVLFAKEGAKVVCADLNEAGIQKTLDKIKELVGEGNAIGVKTDVSKEDQVKALVDKAVEEYGKLSIMFNNAGIMHPQDDNALNTEEKIWDLTMNINVKGVWYGCKYAIIAMRKSGGGSIINTASFVALMGAATPQLAYTASKGAVLAMTRELAMVHARENIRFNSLCPGPIRTPLLMDFLNTDEKKQRRLVHVPQGRFGEAIEQAYGALFLASDESSYVTGTDFRVDGGLASAYVTPEGDPQGIVPQNFADS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NI93</accession>
    <name>A0A1C7NI93_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Peptidase M20 domain-containing protein 2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">PM20D2_0</name>
        <name evidence="4" type="ORF">A0J61_03460</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the peptidase M20A family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000149">
        <property type="protein sequence ID" value="OBZ88489.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NI93"/>
    <dbReference type="STRING" id="101091.A0A1C7NI93"/>
    <dbReference type="InParanoid" id="A0A1C7NI93"/>
    <dbReference type="OrthoDB" id="6119954at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016805">
        <property type="term" value="F:dipeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05672">
        <property type="entry name" value="M20_ACY1L2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.360:FF:000004">
        <property type="entry name" value="Peptidase M20 domain-containing protein 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.360">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.10">
        <property type="entry name" value="Zn peptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017439">
        <property type="entry name" value="Amidohydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036264">
        <property type="entry name" value="Bact_exopeptidase_dim_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002933">
        <property type="entry name" value="Peptidase_M20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052030">
        <property type="entry name" value="Peptidase_M20/M20A_hydrolases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011650">
        <property type="entry name" value="Peptidase_M20_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017144">
        <property type="entry name" value="Xaa-Arg_dipeptidase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01891">
        <property type="entry name" value="amidohydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30575">
        <property type="entry name" value="PEPTIDASE M20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30575:SF0">
        <property type="entry name" value="XAA-ARG DIPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07687">
        <property type="entry name" value="M20_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01546">
        <property type="entry name" value="Peptidase_M20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037226">
        <property type="entry name" value="Amidohydrolase_ACY1L2_prd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55031">
        <property type="entry name" value="Bacterial exopeptidase dimerisation domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53187">
        <property type="entry name" value="Zn-dependent exopeptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase M20 dimerisation" evidence="3">
        <location>
            <begin position="174"/>
            <end position="263"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006247"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRNR" id="PIRNR037226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF07687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OBZ88489.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="398" mass="43500" checksum="2B0DBC71C8FACB8A" modified="2016-11-30" version="1">MNTEIRESIAHTIKSLDRELREISIKIHDDPELGNKEFHAHDLLTDYLEKKGFKVTRKAAGLETAFLAEFSNSSSDRRVGFVCEYDALPGVGHACGHNIITVQGLASALSLKTLMEHDLVKGKVVLFGTPAEESTSGKINFIKTGLLQNSVDVAMMLHPFAKDSLYGKMLALDTLEVEFFGKASHAGMAPWNGINALDALMQSFDNVGLLRQQILPTDRVHGIITNGGKSANVIPDYASAKFMARSVTKNRLSELKEQVDRCFLSAARATGCTVSLKWAAIGPLDDVFMNDAMTATFQHYMEEEGITYPSKAKEEQLTLGSTDMGNFSYVVPSIHPGYGIHTDAANHTKEFAAAAGTEVAHQDTLRAAKCLSLTAAEILRDDKLYEQIVADFKKGKAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NII2</accession>
    <name>A0A1C7NII2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_04802</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000242">
        <property type="protein sequence ID" value="OBZ87154.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NII2"/>
    <dbReference type="InParanoid" id="A0A1C7NII2"/>
    <dbReference type="OrthoDB" id="2267457at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008889716" evidence="1">
        <location>
            <begin position="20"/>
            <end position="275"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ87154.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="275" mass="29255" checksum="FC03C8293EDC6E6C" modified="2016-11-30" version="1">MKPAFVGLFVLSLSQLCSAVDPIRTQVLVEFPMIFNDPFRACIDTPSCGITCFQLQYYQKDSKALSSNGCPAITPYSTSSRLDTLDYLLYPFKDEPVPCTLIRVSGEGIIYLCSEDFNTNNAGGASSSTTTTLTTTTTTTTPAATVTATIAVPTCLSEETIFGKKKGNGYSGDCCKTEADCKNDCVMGRCNGPKRATTKAITVKSNTAVSSPITKKAAITTTTTKSTTKTTIKATKTPSVCRPGYLGKKNGKGSKGACCNTHWDCKEECVKGSCN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-06-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NIM4</accession>
    <name>A0A1C7NIM4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_02990</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000121">
        <property type="protein sequence ID" value="OBZ88972.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NIM4"/>
    <dbReference type="InParanoid" id="A0A1C7NIM4"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ88972.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="84" mass="9774" checksum="66055BD43F7EF60C" modified="2016-11-30" version="1">MSSEDIEMMLDIVSNSLFQCILPHNPNREYYDRYRLSAAITEDTINVSDETYNCHISLFPNGSKGFIQSRMQFCKALTLTYEHD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NIP0</accession>
    <name>A0A1C7NIP0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">SMP-LTD domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">A0J61_02980</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000121">
        <property type="protein sequence ID" value="OBZ88963.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NIP0"/>
    <dbReference type="FunCoup" id="A0A1C7NIP0">
        <property type="interactions" value="29"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NIP0"/>
    <dbReference type="InParanoid" id="A0A1C7NIP0"/>
    <dbReference type="OrthoDB" id="26740at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032865">
        <property type="term" value="C:ERMES complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008289">
        <property type="term" value="F:lipid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990456">
        <property type="term" value="P:mitochondrion-endoplasmic reticulum membrane tethering"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015914">
        <property type="term" value="P:phospholipid transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd21675">
        <property type="entry name" value="SMP_TEX2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031468">
        <property type="entry name" value="SMP_LBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13466:SF19">
        <property type="entry name" value="NUCLEUS-VACUOLE JUNCTION PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13466">
        <property type="entry name" value="TEX2 PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51847">
        <property type="entry name" value="SMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="6" id="KW-0445">Lipid transport</keyword>
    <keyword evidence="7" id="KW-0446">Lipid-binding</keyword>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="6"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="domain" description="SMP-LTD" evidence="11">
        <location>
            <begin position="229"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="650"/>
            <end position="671"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004586"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="OBZ88963.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="671" mass="75719" checksum="2499771DDE1F13E0" modified="2016-11-30" version="1">MVSLNIIAAYILGGFTLFPILLITLCIVYFVHSKIISPLHRLFINKDRKLSEDFPLLEKTDEPANGSSSALLYKVGWLQVSQDEEPSTPDTIGNMVKNYISGKAGKKENNVFFAVLKYNTLYLYDSEKQLDCRGVINLTHYAIYTHPPGLQDYELFSKPNLIKLESTIGKTYFINCHKCIDKEDWYFAFIRASRSKLPTQTTGDCMKDKTHFDQSAMNHLITVVHSDEHHFQTQWLNAILGRIFFGVYRTQEIKDALYKKVITKLDKINAKRPPFLGEITVRSVDPGHSSPRFTQPKLLGLSPTGELSAEAHLEYDGGFRIEIETSLKWKYSDRLKPFTIDLVLGITLKEIGGKVLIKIKEPPTNRFWYAFYECPKMEWKVEPVVWEKRVGYSVVVKAIETKIQEFIMETMVLPYFDDIIFFPTNGAGGIFEVPPSLSTAENDTTKQQKETVTPVELVLEKDESVEETEKNKKLKKQDQVKRFQEDEALLSTAKSLPELFSAVPDRQQQQQQQQEDDDYRHIIEREKISYTSPILIPSSDEKDFVSMSTSLSTSPDSLLSSSPCSITLDDSLQSHVDGAPIMPTTSTSLTTTTTCDSSVSSSIQITYTMDDKSGDSTDSNKVRLRKSSSLALLKPKTGASTAVNVLPAMAHKAQQSPEKKNLESISVTTVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NJH3</accession>
    <name>A0A1C7NJH3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Outer spore wall protein LDS1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">LDS1</name>
        <name evidence="6" type="ORF">A0J61_02711</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000106">
        <property type="protein sequence ID" value="OBZ89225.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NJH3"/>
    <dbReference type="InParanoid" id="A0A1C7NJH3"/>
    <dbReference type="OrthoDB" id="10012223at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059112">
        <property type="entry name" value="CysZ/EI24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052786">
        <property type="entry name" value="Spore_wall_assembly"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34292">
        <property type="entry name" value="OUTER SPORE WALL PROTEIN LDS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34292:SF2">
        <property type="entry name" value="OUTER SPORE WALL PROTEIN LDS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07264">
        <property type="entry name" value="EI24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50096">
        <property type="entry name" value="IQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="34"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="181"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="240"/>
            <end position="260"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OBZ89225.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="290" mass="32682" checksum="2DEE04AC721168EE" modified="2016-11-30" version="1">MFTLLRERRLPTATYPLRGLAHFLHHPGSSAGPIAFSIVKVIATSSLALFPLYRYGYSFQKGILTAAYKALFNNGTTPSYLASLLIAATSTLVCIAETSAITMQLGNHFVGSVRARVFDSVLKERHGLXDENDMALVSEKVGGPATDLTMPKYHFLSPYNLMIVSAQEDNDWPIFFLRSALFVLTLPLNVVPVIGPIAFINIQALFRGGMAHQRYFQLYKWTPVQRQRRIELHFWQYQRFGLVATLLEMIPVAGYLFIYTNQIGAAMWAMDLHDLKMLDKDNIPDHLKSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NJK9</accession>
    <name>A0A1C7NJK9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">GATS-like protein 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">GATSL3_0</name>
        <name evidence="2" type="ORF">A0J61_02675</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000104">
        <property type="protein sequence ID" value="OBZ89265.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NJK9"/>
    <dbReference type="InParanoid" id="A0A1C7NJK9"/>
    <dbReference type="OrthoDB" id="58529at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006520">
        <property type="term" value="P:amino acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046394">
        <property type="term" value="P:carboxylic acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2130.10">
        <property type="entry name" value="VC0802-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045865">
        <property type="entry name" value="ACT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027795">
        <property type="entry name" value="CASTOR_ACT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051719">
        <property type="entry name" value="CASTOR_mTORC1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31131:SF6">
        <property type="entry name" value="CASTOR ACT DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31131">
        <property type="entry name" value="CHROMOSOME 1, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13840">
        <property type="entry name" value="ACT_7"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55021">
        <property type="entry name" value="ACT-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CASTOR ACT" evidence="1">
        <location>
            <begin position="80"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="domain" description="CASTOR ACT" evidence="1">
        <location>
            <begin position="265"/>
            <end position="326"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ89265.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="346" mass="39218" checksum="A215CA37E8876F1C" modified="2016-11-30" version="1">MITILPSKVKLLHFPKSHLQHVTHAIVKSCLFRDINDEQYFFSFTENAYEVSIIATKDIIDNDFIPLLVMSQCLEMRTSNNLYRVLQVDDEGGQDTSGKRISDLSCPLAKSKFSIFYMSTYQTDFVLIREQRLNRAVELLKEHKFEFDQDSIEQFLGGSPLSLTQENNRLSILSESSAVLEEDFEKSVLTDELRCVGLNPHYRSDWSMTILKILSYPELISASSKSEETRFFSYTATSDGISLIANQAILNLFNQDAIFQDEESQTYRVIQVNLAGSNLDRCGIVWSISHPLATEASINLLYLSTFMSANVLVSSDDLGRAEKILAEDLENIKGMLAEIVLEPTME</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NJV0</accession>
    <name>A0A1C7NJV0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 4">Adenylyl cyclase-associated protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">cap1</name>
        <name evidence="7" type="ORF">A0J61_04391</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">The N-terminal domain binds to adenylyl cyclase, thereby enabling adenylyl cyclase to be activated by upstream regulatory signals, such as Ras. The C-terminal domain is required for normal cellular morphology and growth control.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the CAP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000214">
        <property type="protein sequence ID" value="OBZ87564.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NJV0"/>
    <dbReference type="FunCoup" id="A0A1C7NJV0">
        <property type="interactions" value="344"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NJV0"/>
    <dbReference type="InParanoid" id="A0A1C7NJV0"/>
    <dbReference type="OrthoDB" id="77251at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003779">
        <property type="term" value="F:actin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008179">
        <property type="term" value="F:adenylate cyclase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007015">
        <property type="term" value="P:actin filament organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019933">
        <property type="term" value="P:cAMP-mediated signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.330:FF:000001">
        <property type="entry name" value="Adenylyl cyclase-associated protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.330">
        <property type="entry name" value="Adenylate cyclase-associated CAP, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001837">
        <property type="entry name" value="Adenylate_cyclase-assoc_CAP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013912">
        <property type="entry name" value="Adenylate_cyclase-assoc_CAP_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013992">
        <property type="entry name" value="Adenylate_cyclase-assoc_CAP_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017901">
        <property type="entry name" value="C-CAP_CF_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016098">
        <property type="entry name" value="CAP/MinC_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036223">
        <property type="entry name" value="CAP_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018106">
        <property type="entry name" value="CAP_CS_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053950">
        <property type="entry name" value="CAP_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036222">
        <property type="entry name" value="CAP_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006599">
        <property type="entry name" value="CARP_motif"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10652">
        <property type="entry name" value="ADENYLYL CYCLASE-ASSOCIATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10652:SF0">
        <property type="entry name" value="ADENYLYL CYCLASE-ASSOCIATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08603">
        <property type="entry name" value="CAP_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21938">
        <property type="entry name" value="CAP_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01213">
        <property type="entry name" value="CAP_N-CM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00673">
        <property type="entry name" value="CARP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69340">
        <property type="entry name" value="C-terminal domain of adenylylcyclase associated protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101278">
        <property type="entry name" value="N-terminal domain of adenylylcyclase associated protein, CAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51329">
        <property type="entry name" value="C_CAP_COFACTOR_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01088">
        <property type="entry name" value="CAP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="C-CAP/cofactor C-like" evidence="6">
        <location>
            <begin position="361"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="42"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="251"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="321"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="254"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="270"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="332"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007659"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00054756"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00072052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000647"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OBZ87564.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="524" mass="55956" checksum="AC00C6BF7BA15C26" modified="2016-11-30" version="1" fragment="single">TYNTMSEFHSLANLIKRLEVATTRLEDLAMSSSSASAVAAKSPSSPKAIAPANNTTATSTSAASTTEIPAAVEKHDDAIKASLEKYLNLSQELGGLVAEQAALVKQAIAAEKDIIYISTLSQKPDMTSPTFMKLLEPIQKSLGSIMEIKDANRPDPLFNHLSTVAEGIPALGWFTCEPTPVPFIRDMKDAAQFYSNRVVKEWKEKDAKHVEWSQAFLGLLESLAVYVKENFPTGLTWNANGEKPEAVADKSLSATTTTAAAPAAPAPAAGGPPPPPPPPPPMVIEDDQKPAQASNSGAAAVFAEINKGSSVTANLRKVDKSEMTHKNPSLRASSSVTVATPTSPKRQGPPTPNKPDKYTLKKAAKTSLEANKWVVENHENNHDIVIEETAINQAVYIFNCKNSTIRIKGKVNAVTIDSCTKCGIAVDSTVSTVDVVNSKSFALQVFKVVPTIAVDKCDGGEIYLSKDCLGVELLSAKSTSLNVLLPEQAAEHDDIEYKEVPVPEQFKTTIVDGKLVTVTVEHAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NJY0</accession>
    <name>A0A1C7NJY0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Mid2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_02854</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000114">
        <property type="protein sequence ID" value="OBZ89099.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NJY0"/>
    <dbReference type="STRING" id="101091.A0A1C7NJY0"/>
    <dbReference type="InParanoid" id="A0A1C7NJY0"/>
    <dbReference type="OrthoDB" id="10610883at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="209"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="151"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="267"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="14"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="36"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="278"/>
            <end position="287"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ89099.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="287" mass="30173" checksum="AC5B8BE8501C141B" modified="2016-11-30" version="1">MAPTHILIQKRADDEDDSSTEDDSSTEEGSSTDGDSSADTDSSTDGDTSDNADSNEDDSTDESNQDDGNDNDDEGDDTNDDEGDDTNDDESEEDGTSDDTSTEQLATSTEADILPTSTVDQDITTTIDSVTTQITSALEPTTTLETAQITSTLEPTTSTTLDPIISTSTAPTSTMIAPSSTTSLNATPSIIAVAAEVTDNSDNGAQKKALIGGIVGGVGGALLLGLLAFVAVARYRKQRRERGMETFRPKSEYSVFNGGGGGRMSEIPSSYYHPSIERTPSVTRNQY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NKA5</accession>
    <name>A0A1C7NKA5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Cytochrome P450</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">A0J61_02520</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1 8">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000096">
        <property type="protein sequence ID" value="OBZ89438.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NKA5"/>
    <dbReference type="STRING" id="101091.A0A1C7NKA5"/>
    <dbReference type="InParanoid" id="A0A1C7NKA5"/>
    <dbReference type="OrthoDB" id="1470350at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050196">
        <property type="entry name" value="Cytochrome_P450_Monoox"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24291:SF50">
        <property type="entry name" value="BIFUNCTIONAL ALBAFLAVENONE MONOOXYGENASE_TERPENE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24291">
        <property type="entry name" value="CYTOCHROME P450 FAMILY 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 7 8" id="KW-0349">Heme</keyword>
    <keyword evidence="5 7 8" id="KW-0408">Iron</keyword>
    <keyword evidence="3 7 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 8" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="4 8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" description="axial binding residue" evidence="7">
        <location>
            <position position="469"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OBZ89438.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="525" mass="60676" checksum="C04356F1BE9F5920" modified="2016-11-30" version="1">MLIENAMEIYHRIAQKTLFVLKKQPAFSYITAAIILFLSSEIYRQVAVPKHLRPFARVSFLSLVRSFMRKDSVVERNKKLIAPIVNQGHKVYVAKLPFEWSLSIADSELAKMVLLKSDMFPKSQDFRNKLGEDNIIVRFMGSENVALANGHKWKKQRKFMNPAFHRSMPINTFGNLMFRLFDRIDEQPHDFPVSIRLKNFTLDALGLAAFDFDFKALLGDPDGWTKTYDTIMKSLFDPWIFLFSNIDFILQAILPSRRQSTAAVIKFNKMLIDMAERRRQEIQRGEKKAVPDNEKDLLTLLIEADLEEGNTATNDELRENIALFFLAGHDTTGNALSFCLYNLAKNKHVQDKLREEIVSVMNDRDPDAIPTAEDFKKMPYLNMVIKENLRLSGPVDRLFSRVTTEDIVMEGHVVPKGTYINVDIASLHFNPNYWHDPQSFIPERFEDDGEHSHHAGMTWLPFSNGSRQCLGMNFSLTEQRVFLAMLLKRYVVDISKDSIHYDKVVYDKLFNFAPASLTLNFTKRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NKT6</accession>
    <name>A0A1C7NKT6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">RING-type E3 ubiquitin transferase</fullName>
            <ecNumber evidence="6">2.3.2.27</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">ufd2</name>
        <name evidence="13" type="ORF">A0J61_02266</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.</text>
            <dbReference type="EC" id="2.3.2.27"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="4">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the ubiquitin conjugation factor E4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.27" evidence="6"/>
    <dbReference type="EMBL" id="LUGH01000083">
        <property type="protein sequence ID" value="OBZ89675.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NKT6"/>
    <dbReference type="FunCoup" id="A0A1C7NKT6">
        <property type="interactions" value="1165"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NKT6"/>
    <dbReference type="InParanoid" id="A0A1C7NKT6"/>
    <dbReference type="OrthoDB" id="20295at2759"/>
    <dbReference type="UniPathway" id="UPA00143"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000151">
        <property type="term" value="C:ubiquitin ligase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034450">
        <property type="term" value="F:ubiquitin-ubiquitin ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036503">
        <property type="term" value="P:ERAD pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000209">
        <property type="term" value="P:protein polyubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006511">
        <property type="term" value="P:ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd16657">
        <property type="entry name" value="RING-Ubox_UBE4A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.40.10:FF:000055">
        <property type="entry name" value="Ubiquitin conjugation factor e4 a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019474">
        <property type="entry name" value="Ub_conjug_fac_E4_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045132">
        <property type="entry name" value="UBE4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003613">
        <property type="entry name" value="Ubox_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13931:SF2">
        <property type="entry name" value="UBIQUITIN CONJUGATION FACTOR E4 B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13931">
        <property type="entry name" value="UBIQUITINATION FACTOR E4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04564">
        <property type="entry name" value="U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10408">
        <property type="entry name" value="Ufd2P_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00504">
        <property type="entry name" value="Ubox"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51698">
        <property type="entry name" value="U_BOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0808">Transferase</keyword>
    <keyword evidence="9" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="U-box" evidence="12">
        <location>
            <begin position="1014"/>
            <end position="1088"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="39"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="48"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="88"/>
            <end position="104"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00007434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00012483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51698"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="OBZ89675.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="1098" mass="125617" checksum="AA63322691B205A1" modified="2016-11-30" version="1">MENDQNISDADRVIFSQKKRISNETNSVFLEQIRLKRLAKLQQQQQQPHSGSNESKPTSSTKTALPTLDEFVPLKKPTPKKTSIETTPSPQQQQQQQIKSSPQSATSPVTKPAKSFEEWQDDVLSRVLQVTLNPSNMYKQGKCVYLSGLAEELVEENGKPYPNRLSEKMLDRIIVARLSLDPTEPDPSLPQDIACTLQLPDFDYLLQCWKTAHEIRKNTAFRSKNLEKSILDQRLAVLDNVKALIVSYSGLVLQMPDMFPQLHSDQLGPKQLVSRLKALPDTSEGLPTEYLIELVSRFNEDGLDMILGPAIALLSQEISRQNILSEFKPSMQSIAYLSENKSIASMLTTLEEFDPSHATAKNIEQISLMGPLFRLSAYPDNTSKVAENYFQNAEGRNAADLESSKNGLRGSVLNIQRTMFGICNSMVRANANSRDQLLSYFGHIVKLNEKRAQMQVDPETVSSDGFMHNIAAVLLSFCDPFMDLRASKIDKIDPTFFRTSKRLDVTEDTKINATKEQSDAYYGEQQPLKAHNFITEIFFMTLSFMHYGPIRAYVNFNEFIREYNETKKQTERAQQEALRTANTPQGVMSDFVAKRMKAKLEQMTTYRLAYEAMLLDSTFLSEALRFYDLVMAWLIRLVDPNHKHPWEKVNLPLPSQVPDAFAMLPEWIIEDIVELFIFIGKYGYETNVMRDHPHDELVAFIVTFLRNAKYVKNPYLKAKLVEILFFFTYPIAKGVPGELENILNSHPLALQHLVPSLMNFYVEVEQTGASSQFYDKFNIRYNISHVMKTIWSHPAHRAKLREESRNSTNFTRFVNMLMSDVTYLMDESLSKLTEIHQIQLEMNDQATWEAQTPQHRQEREGSLPSLERQAQSYVALGNETVHMLNYMTSEVVEPFLVNEIVDRLAAMLDYNLVQLVGPKCTELKVANPEKYHFQPRKLLSEIIDVYLNLNSPVFVQAVARDGRSYRKEYFSKAAFILQKHNIRSTDHINALEKFVHQVELAIQSGVEEEEELGEVPDEFLDPIFFTLMEDPVLLPTSSVIVDRSTIRAHLLGDTRDPFNRMPLTMEMVEPATELKQKIADWKAEQKGKKVSESMDTSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NL18</accession>
    <name>A0A1C7NL18_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Actin-related protein 2/3 complex subunit 4</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">Arpc4</name>
        <name evidence="7" type="ORF">A0J61_02431</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5 6">Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the mother actin filament.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
            <location evidence="6">Cytoskeleton</location>
            <location evidence="6">Actin patch</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the ARPC4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000091">
        <property type="protein sequence ID" value="OBZ89519.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NL18"/>
    <dbReference type="FunCoup" id="A0A1C7NL18">
        <property type="interactions" value="453"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NL18"/>
    <dbReference type="InParanoid" id="A0A1C7NL18"/>
    <dbReference type="OrthoDB" id="336240at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030479">
        <property type="term" value="C:actin cortical patch"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005885">
        <property type="term" value="C:Arp2/3 protein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051015">
        <property type="term" value="F:actin filament binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0060090">
        <property type="term" value="F:molecular adaptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044396">
        <property type="term" value="P:actin cortical patch organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030041">
        <property type="term" value="P:actin filament polymerization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034314">
        <property type="term" value="P:Arp2/3 complex-mediated actin nucleation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1460.20:FF:000001">
        <property type="entry name" value="Actin-related protein 2/3 complex subunit 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1460.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034666">
        <property type="entry name" value="ARPC2/4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008384">
        <property type="entry name" value="ARPC4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22629:SF0">
        <property type="entry name" value="ACTIN-RELATED PROTEIN 2_3 COMPLEX SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22629">
        <property type="entry name" value="ARP2/3 COMPLEX 20 KD SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05856">
        <property type="entry name" value="ARPC4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF039100">
        <property type="entry name" value="ARPC4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69645">
        <property type="entry name" value="Arp2/3 complex subunits"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0009">Actin-binding</keyword>
    <keyword evidence="2 6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 6" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00054835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRNR" id="PIRNR039100"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OBZ89519.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="169" mass="19516" checksum="FF976A315C93A950" modified="2016-11-30" version="1">MSNTLRPYLTAVRSTLTAALCLENFSSQVAERHNTPEVESGKSKELLMNPLVISRNENEKVLIESSVNSIRVSIKIKQADDLERILCHKFARFLMMRAESFVILRRKPVEGYDISFLITNNNTEQMYKHKLVDFIVHFMEEVDKEISEMKLSVNTRARTVAESYLVQFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-06-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NLS2</accession>
    <name>A0A1C7NLS2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_01902</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000066">
        <property type="protein sequence ID" value="OBZ90047.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NLS2"/>
    <dbReference type="InParanoid" id="A0A1C7NLS2"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ90047.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="61" mass="7176" checksum="4D879DF8BE444221" modified="2016-11-30" version="1">MRMSNRLKTAYDINFLLLDRVTERPEGLTTYTYHHGADNDFLGLKPNKRHDQNAEMLILIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NLV1</accession>
    <name>A0A1C7NLV1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DinB-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_01847</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000064">
        <property type="protein sequence ID" value="OBZ90092.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NLV1"/>
    <dbReference type="STRING" id="101091.A0A1C7NLV1"/>
    <dbReference type="InParanoid" id="A0A1C7NLV1"/>
    <dbReference type="OrthoDB" id="5564877at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39473">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39473:SF1">
        <property type="entry name" value="DINB-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ90092.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="186" mass="21233" checksum="1C436FC5E50A819E" modified="2016-11-30" version="1">MPPKNENSVTQPETSMQVMSTDLLQQAIDLLQLIENDQYTKISDVMPGSTIGKHLRHLYDHFRLLYAKCDDIPDNWIVDYDIRARNDPSESDRLIAIDRFKEMQSVVRKNSHVSLDTPLTLSATITAADNNKYQFSSSFGRELFYCCIHAIHHYASIKAICVEQNISTPKEFGVAPSTLQELQKKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NLV4</accession>
    <name>A0A1C7NLV4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">V-type proton ATPase subunit D</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">vma-8</name>
        <name evidence="5" type="ORF">A0J61_01811</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the V-ATPase D subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000062">
        <property type="protein sequence ID" value="OBZ90133.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NLV4"/>
    <dbReference type="FunCoup" id="A0A1C7NLV4">
        <property type="interactions" value="314"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NLV4"/>
    <dbReference type="InParanoid" id="A0A1C7NLV4"/>
    <dbReference type="OrthoDB" id="7676488at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000329">
        <property type="term" value="C:fungal-type vacuole membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045121">
        <property type="term" value="C:membrane raft"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000221">
        <property type="term" value="C:vacuolar proton-transporting V-type ATPase, V1 domain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046961">
        <property type="term" value="F:proton-transporting ATPase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007035">
        <property type="term" value="P:vacuolar acidification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.3240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00271">
        <property type="entry name" value="ATP_synth_D_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002699">
        <property type="entry name" value="V_ATPase_D"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00309">
        <property type="entry name" value="V_ATPase_subD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11671">
        <property type="entry name" value="V-TYPE ATP SYNTHASE SUBUNIT D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01813">
        <property type="entry name" value="ATP-synt_D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0406">Ion transport</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="212"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="227"/>
            <end position="242"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OBZ90133.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="259" mass="29126" checksum="B08246A6A0421750" modified="2016-11-30" version="1">MSGNNQRLNIFPTRMALTNMKLKLKGAQTGHSLLKRKSEALTKRFRGITVKIDELKRKMGQVMQLASFSLAEVQYITGDISYQIQEGSKNAQLRVRAKQENVSGVMLPAFEMYSEGGNAFEFTGLGRGGQQIQRAKEVYAKAVETLVELASLQTAFVILDEVIKATNRRVNAIEHVIIPRYENTIKYIISELDEQDREEFFRLKKVQGKKKDHAAAEEAARIQGASDAEKEGREAPTLHAADETGQLNILDHEDEDLIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NM52</accession>
    <name>A0A1C7NM52_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_01789</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000061">
        <property type="protein sequence ID" value="OBZ90167.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NM52"/>
    <dbReference type="InParanoid" id="A0A1C7NM52"/>
    <dbReference type="OrthoDB" id="2257446at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008889783" evidence="1">
        <location>
            <begin position="20"/>
            <end position="192"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ90167.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="192" mass="19576" checksum="45E7A79AD5AC56BB" modified="2016-11-30" version="1">MKFFTAVSGIVLAVSGVAAQLTAPMQNYNVSSPVSNGPYVAGQVLPCTIQLFDTVPTVPQLTISLTSATSSNVSYVISSSVDVSKTSASAKQNGNVTYYEHSVNYNIPSTVTPGTYNVVFLDTLTNTHLDVPINVLPVASTPSASSAAGTGSSASPTASIFKPSSDVGSMAPGLTTKVIVSLAGVAALAYMF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NM57</accession>
    <name>A0A1C7NM57_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_01859</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000064">
        <property type="protein sequence ID" value="OBZ90080.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NM57"/>
    <dbReference type="STRING" id="101091.A0A1C7NM57"/>
    <dbReference type="InParanoid" id="A0A1C7NM57"/>
    <dbReference type="OrthoDB" id="2351940at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="29"/>
            <end position="40"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ90080.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="289" mass="32624" checksum="0964EFFCEDE1F45B" modified="2016-11-30" version="1">MSYDDQEQFVQETPANAPRLPRHNPFTNRPIPRSSRLRPPQAIVYRDPEGNIIGERPSNISSAISITRANYLDPLSESVLDPGVFHTADISCTQDERAVNLSLLCHQQLERIPTSHNYVPLGFDIIFQDGGQYSYNYAIQNILRNDQSIYCASRCGTVNILLRFKGSKSNEFRRSQCCYLSHIIIKAPLYGTSFKYGMVFISNQPIDIEVTRPYNLYHEQPVEDNGFSVTWFNPPSLPSQQVSLIHLNGKSAKYVLIKLIGAESECVNLEYIGFVGYVGSRCFASAKLC</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NMA2</accession>
    <name>A0A1C7NMA2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_01669</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000056">
        <property type="protein sequence ID" value="OBZ90283.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NMA2"/>
    <dbReference type="InParanoid" id="A0A1C7NMA2"/>
    <dbReference type="OrthoDB" id="2202112at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008889784" evidence="1">
        <location>
            <begin position="20"/>
            <end position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ90283.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="88" mass="9970" checksum="2227A5E62ACB0C0F" modified="2016-11-30" version="1">MKSISCGFLLLLCLLAVEAGSYHRRQYVDSSLLKKREEDCDLTCHEIENACAVKCGSEGSKMNRELRHVCYQGTCYCGFELQPDSEKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NMI5</accession>
    <name>A0A1C7NMI5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_01590</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000052">
        <property type="protein sequence ID" value="OBZ90373.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NMI5"/>
    <dbReference type="STRING" id="101091.A0A1C7NMI5"/>
    <dbReference type="InParanoid" id="A0A1C7NMI5"/>
    <dbReference type="OrthoDB" id="2290036at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="51"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="63"/>
            <end position="86"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ90373.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="132" mass="15448" checksum="904544F427DFCEC0" modified="2016-11-30" version="1">MYELIDEKDFLKDGDAKSQIKSFIQEKGELMETADKEDKEYAKQKKLEKKIKRKERERAAMRDEEDGSMDEDEAMSGSESESESEEEDRKRKWFEDSESEEEDSSNKKRVIDIEEPQTLEDQEALALKLLGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NMU7</accession>
    <name>A0A1C7NMU7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Neurofibromin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">Nf1_1</name>
        <name evidence="5" type="ORF">A0J61_01492</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000048">
        <property type="protein sequence ID" value="OBZ90453.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NMU7"/>
    <dbReference type="InParanoid" id="A0A1C7NMU7"/>
    <dbReference type="OrthoDB" id="28245at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00170">
        <property type="entry name" value="SEC14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.525.10">
        <property type="entry name" value="CRAL-TRIO lipid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.506.10">
        <property type="entry name" value="GTPase Activation - p120gap, domain 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001251">
        <property type="entry name" value="CRAL-TRIO_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036865">
        <property type="entry name" value="CRAL-TRIO_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039360">
        <property type="entry name" value="Ras_GTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023152">
        <property type="entry name" value="RasGAP_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001936">
        <property type="entry name" value="RasGAP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008936">
        <property type="entry name" value="Rho_GTPase_activation_prot"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10194:SF142">
        <property type="entry name" value="NEUROFIBROMIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10194">
        <property type="entry name" value="RAS GTPASE-ACTIVATING PROTEINS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13716">
        <property type="entry name" value="CRAL_TRIO_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00616">
        <property type="entry name" value="RasGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00323">
        <property type="entry name" value="RasGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52087">
        <property type="entry name" value="CRAL/TRIO domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48350">
        <property type="entry name" value="GTPase activation domain, GAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00509">
        <property type="entry name" value="RAS_GTPASE_ACTIV_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50018">
        <property type="entry name" value="RAS_GTPASE_ACTIV_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0343">GTPase activation</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ras-GAP" evidence="4">
        <location>
            <begin position="1273"/>
            <end position="1463"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="812"/>
            <end position="849"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="812"/>
            <end position="822"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="837"/>
            <end position="847"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022468"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50018"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OBZ90453.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="2648" mass="298138" checksum="0167B920A2F15ECF" modified="2016-11-30" version="1">MRTSAKLIGNLVHRVSVRLPYKSGRKLDTVEQDPIVKQTVAAIVELSKFKLSTIANSLGYVLENMSKSHQLYEQSVPVDVMQSELFILRLLSACTQHHWQHCRELEAQKNPDTPSNLSQNVLPPLDAALVSFLLMLLGRYVSQYHALEESTNAATGKNPPSFIDYGENESGYSPEQIRFSLLSDMYKEASKVLYYISASNWEACYAKIKNAIISLDSINASSDGIPSEIRMLGSSCLTRDRLFTIFTELSPYYLHMRHEGKLLFSKMVRRAIWKWIEELPMEYAEVCAGVGRSLSGSEVLFDMCNSTADNPRKRAILWPLQTILLSLSPELLMQAFLDTAPTHNRRANFLSLLRKSLQTTRNVDIAAVCYVDLCKAATFVPPDNDSVLRSIAADVQAELKDKVWDFARSSNSDSTLNMSGYTIDQQKLTTDFLLSRLRLRTEDTLKNIIPSCVHSKVHIRFKMALVKVCLIIAQDKNNLAWNPTISSMYNGLCTPLRTLFFQVVNNELTNGVISKRKDTSAAYLNRAELLLDMLELFHLEPSLALLGSDDDRLDQNIAFMSALASLVQHPIQRIRQDSLDLLLKMHHVDIIPHWGPGDNYVYNFGKVGAPVILNISKQILDAKSNEDYHKTLLQFVVTLFKARYTFLKSKREILPNSVYNLRERLQAAIAIEIAVLISLCSPNKEVCDEALRCIGSICKEARMINLSDDEQAYSLSMYSNIKVYEGLSADDSRFVGRKAQQKKIRKFIRMFPEQTPGNMAAWEEAWNRWKQLTVLINRIPDDTIEDDHLENNATQASMANTPHGGLVTITNTNSTSLSNSNSKKLPLTRAGGDKMTRNGSSNSTLVISSPKPQPSLEFFEEKAAEWQNYTGFLAALGGCCLLESKNAKKTNSIMEHSRRISSPSEPAMMVDRFVSDMVDLLVCDNVRLREGIKDIIGNDLSPALYVSLFRHFDIYMGRCFNSNGEVIRSPQNKLFVEQTVLSLRLILDRLVNPSDCLLNVDFGVLMNKAANYLNGLPNTYITMRIKIKMCFFIEAIMQKKEQIIIQDEMRLRNKLLEIIIEWTSDFMTPAEVGQHVDRLQKDLDQACLKAIVSLLQQLPLQPPEAVRPEEIVRIKSKMFLKYFSFFRKLLDRYKQSERDISKPLVSGPISSQLLSPRDSSFKPVASGSTNASTSDSYADIGHLKELTILAMSRLLSANVDAGLKYSLSMGYDEDHETRKAFMQVLTNILDHGTEFETLAEDVMIDRYEKLIDMLVDSDMDIVMSLCEVCPSPDTTDVAEVLLICFESRSKVMPLLRAVVQREISMTGKGTTMATRILSIFAKLSCLDYIRITLQPAMEAINALPDDQLTWELDPTKISPNEEIAKNKKNVVRATEIFLDAICNSVNNAPKAFREELALITEAVSSRFPEAKSTAVGGFVFLRLFGPAILTPEQAGFSKQALPRNVNVRKILLQATRIMQNLANNVLFGSKETHMIVLNDFLTSNIYKVTSFLRAISVVPADMADSTAATFRMDQSGYVRLHKYLYDNLERMSRDLTTRRLIKSSSDDQTQSLLNWKRTLDRLSSLLAQLGTPAEISSSNLSYTRNYTVANSSHVYNELMRRNGHRDVSSINGSNMFYLGGLSKDGRPVFYMICRDLDVEETDYELLTYYMLRVMEPYLNQPFEFLFDLTEFTSSRSIPINFFTQFFQLVLSEMNDYLVTLHLYNPTIFMAKRIRQLPRDIVNKLVKRAKFHTSLAELSEVIAPNQIKLPKQTMEMERENYTTISPVSRISNLKSSLPVTVKIGEEHIQIVTVKKQEIINNLITVYRDVLHISDISDIIPLPSSKPENGGEVSIKYDKGKSIMILSTTKRDMLVQKFPLFLYKLLRQTKQRYESSQPSSISERVIRPNDVPGRLLNMALVNIGSEHPGLRLTAYNLLYSVSVAFRFDTGNQLLKSKDLCIPSNSSNFIVNISESLAQSEMHLTLEFLNEALTGLLKCDDSMRQLCLDYMAPWLNNLAVYARHSPDDHKKNLAKTKDVIKLLIDLTVQRSEMYKHIQTKIWRTLGQIDEITNLVIDCFIQYSVENGVGSPQAEIIADTLVTMSSISIRGKVISRMRRVIEQTSVQPCRHLIEHASWDEIAVLLRFILMLSFNSTGPVVPHIPEIFHIVSLLVVTGPTLIRSSVHELVVNTIHNLCTIGAPLAEDNVKKLHFVLNDVCDSKNRVSFGLTKQHANAFTITKETTTDFAEAIDLTSLQHIVRLLLDALNFGAPTIDVANMWRARWMGLVTSTAFYFNPAIQPRSFVTLGCLAQDEVDDDLIYQILVALKGALAIFNETDSSLIVSIIMCLSNIIDHLPTNSQYLLQLFWLAIALVQVGHASIFQTAVQFLQSVLRALDARNLFVRRSIEDVLLEARAELGDVARELDDICGVNFNNYFSFAIAVLLLKGFKYSENKDTVLHCMTAFLEIDCKQPVEQSFIEARTLGYLAGLLPFASKDDTLRELLRLAGINDTELGGIDLGVSSVGLFGLLEIPDNSTALLLVSLLVTLLNTSDNESEKLFLYSLLADAAVTVPEVFALVYESLLPKMNQMVMNCQNQEVVEAIKCILLTACSEPAFDAVGQASNTSKRTQRWGLESLKFSALCDPNFGAFKTDIGLNAKLASKLLGSITDQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NN35</accession>
    <name>A0A1C7NN35_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Peroxygenase 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">PXG1</name>
        <name evidence="3" type="ORF">A0J61_01444</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the caleosin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000046">
        <property type="protein sequence ID" value="OBZ90507.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NN35"/>
    <dbReference type="STRING" id="101091.A0A1C7NN35"/>
    <dbReference type="InParanoid" id="A0A1C7NN35"/>
    <dbReference type="OrthoDB" id="640742at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007736">
        <property type="entry name" value="Caleosin-related"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31495:SF20">
        <property type="entry name" value="CALEOSIN-RELATED FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31495">
        <property type="entry name" value="PEROXYGENASE 3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05042">
        <property type="entry name" value="Caleosin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="406"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="453"/>
            <end position="528"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="406"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="472"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="486"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="498"/>
            <end position="528"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006765"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ90507.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="528" mass="59405" checksum="5ECE591E48D6C3C5" modified="2016-11-30" version="1">MLIVHSFKGIQRHLKFWDKKDKGYITPIDTISGFMTLGYNMIFSITIGTVIGVFLSLSTQTGWIPDPLCRSNVNRIMSLTKEQTSSGAFDEQGVFIPDQFEQLFQKYAKSDPSGNTITLLEFIQMTKEQEKLNYRPSAWAAGMIELMTAYFFVGHRGTLFKQDVRAAYDGTLFYRLEDTNRYVTQNQSLQGSYLAKPNSMFSIKTFQNRLQPLYDEAQTRSSRMLSYYQFDDWMHHVQQSTLLPRVLRNRQFGVQGVHTPRLVQKKRPMPEELDNLMPEGLTGVATEEQPNEVSISPQNYLSSSFLSKSDMDFYSNNLTLSGVKGSSYSESDSYSPLLISDSVLGVPETVPEEISKASAYDYAPSLTKSVSTSSNDSALQETPLMTGFLRENQDNWLTEGMGLTGVQTEGTKDQSFSETITPPTALDTTEPIESPVLQQQKEEQVTAAGLVTEEQSNDLIEPSITPPPEEQQYVSKPTAPTQERKNNKKVKKNKKNRSGQISPQSNVELSPEQNANTPVHDSWGITQH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NNC6</accession>
    <name>A0A1C7NNC6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">TM7S3/TM198-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">A0J61_01344</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000041">
        <property type="protein sequence ID" value="OBZ90605.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NNC6"/>
    <dbReference type="STRING" id="101091.A0A1C7NNC6"/>
    <dbReference type="InParanoid" id="A0A1C7NNC6"/>
    <dbReference type="OrthoDB" id="102260at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025256">
        <property type="entry name" value="TM7S3/TM198-like_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13886">
        <property type="entry name" value="TM7S3_TM198"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008889798" description="TM7S3/TM198-like domain-containing protein" evidence="6">
        <location>
            <begin position="18"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="148"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="187"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="217"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="242"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="268"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="296"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="343"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="domain" description="TM7S3/TM198-like" evidence="7">
        <location>
            <begin position="165"/>
            <end position="362"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF13886"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OBZ90605.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="385" mass="42870" checksum="FAB927F1168C3A68" modified="2016-11-30" version="1">MKLYLLFLILSIYHAYAVVIQPLPTRTIERGDILKRSATIQGNNKPTQMAVQRHHKRDDIDNALSMYEFWADSCKDDNNNVKVAVSDLNNLWQTITTTVYCGNNQVKTVTKTITAKATSTVTKGGSSGSNDGKKGSGTSCNDKCWSDYLWHTYGFGISVAQGFTGIVLMLIGLYLIIFGFSFFRGTLAVVGFVFFALMSWIGLVNNEPLYGYPHNEIVYICVSAGIGLLGALLFIFLYGISLYFIGVDAGIFLAVFILSWKANLVIEIKVARVCFIVGMGIVLAVLILLTETYCVIFCTAFTGAFLFILGLDLFIHTGLINAFLLIFDGNPNHTNVYIMRVPVYVMLAFVIFLTLVSFGWQYYWNIVSKKKEFGVNVEEKAEGKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NND3</accession>
    <name>A0A1C7NND3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Citrate synthase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">cit-1</name>
        <name evidence="5" type="ORF">A0J61_01355</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the citrate synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000042">
        <property type="protein sequence ID" value="OBZ90597.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NND3"/>
    <dbReference type="FunCoup" id="A0A1C7NND3">
        <property type="interactions" value="448"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NND3"/>
    <dbReference type="InParanoid" id="A0A1C7NND3"/>
    <dbReference type="OrthoDB" id="8017587at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046912">
        <property type="term" value="F:acyltransferase activity, acyl groups converted into alkyl on transfer"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006101">
        <property type="term" value="P:citrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06105">
        <property type="entry name" value="ScCit1-2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.230.10:FF:000001">
        <property type="entry name" value="Citrate synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.580.10:FF:000001">
        <property type="entry name" value="Citrate synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.580.10">
        <property type="entry name" value="Citrate Synthase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.230.10">
        <property type="entry name" value="Cytochrome P450-Terp, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016142">
        <property type="entry name" value="Citrate_synth-like_lrg_a-sub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016143">
        <property type="entry name" value="Citrate_synth-like_sm_a-sub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002020">
        <property type="entry name" value="Citrate_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019810">
        <property type="entry name" value="Citrate_synthase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010109">
        <property type="entry name" value="Citrate_synthase_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036969">
        <property type="entry name" value="Citrate_synthase_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01793">
        <property type="entry name" value="cit_synth_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF007128">
        <property type="entry name" value="PRK09569.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11739">
        <property type="entry name" value="CITRATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11739:SF8">
        <property type="entry name" value="CITRATE SYNTHASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00285">
        <property type="entry name" value="Citrate_synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00143">
        <property type="entry name" value="CITRTSNTHASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48256">
        <property type="entry name" value="Citrate synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00480">
        <property type="entry name" value="CITRATE_SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0808">Transferase</keyword>
    <feature type="active site" evidence="3">
        <location>
            <position position="308"/>
        </location>
    </feature>
    <feature type="active site" evidence="3">
        <location>
            <position position="354"/>
        </location>
    </feature>
    <feature type="active site" evidence="3">
        <location>
            <position position="409"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010566"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR610109-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OBZ90597.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="471" mass="52416" checksum="47EF9598679BCBF9" modified="2016-11-30" version="1">MSALRAFTSLKAATRQSSFRFAPATAIGATRAYSSKVKSLKERVAELVPEKQAEVKAFKKEYGSKVLGEVTVDMAYGGMRGIKGLVWEGSVLDAEEGIRFRGMTIPDCQKVLPGAEEGGEPLPESLFWLLVTGEIPTHEQVKSLSAEWAARSSIPEFVEELIDRCPKTLHPMSQFSLAINALQHESHFAKAYSQGIHKSQYWDPTFEDTMDLIAKLPKVAARIYRNVYKDGKLPEIDQDKDYSYNFSKLLGFEDNKDFVELMRLYLTIHSDHEGGNVSAHTTHLVGSALSDPYLSFAAGLNGLAGPLHGLANQEVLRWTLKLKDSIGVDASEEQIKKYLWDTLNGGQVVPGYGHAVLRKTDPRYTAQREFALKHLPDDPLFGLVSKLYHIIPGVLTEHGKTKNPWPNVDAHSGVLLQYYGLTEQDYYTVLFGVSRALGVTAQLIWDRALLSPIERPKSYSTAHLKKMFGAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NPH5</accession>
    <name>A0A1C7NPH5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Ribosome biogenesis protein RLP24</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">RLP24</name>
        <name evidence="4" type="ORF">A0J61_01157</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the eukaryotic ribosomal protein eL24 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000033">
        <property type="protein sequence ID" value="OBZ90799.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NPH5"/>
    <dbReference type="FunCoup" id="A0A1C7NPH5">
        <property type="interactions" value="700"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NPH5"/>
    <dbReference type="InParanoid" id="A0A1C7NPH5"/>
    <dbReference type="OrthoDB" id="10262490at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030687">
        <property type="term" value="C:preribosome, large subunit precursor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001671">
        <property type="term" value="F:ATPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051117">
        <property type="term" value="F:ATPase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902626">
        <property type="term" value="P:assembly of large subunit precursor of preribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd00472">
        <property type="entry name" value="Ribosomal_L24e_L24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.170.20:FF:000001">
        <property type="entry name" value="probable ribosome biogenesis protein RLP24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.170.20">
        <property type="entry name" value="Ribosomal protein L24e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038630">
        <property type="entry name" value="L24e/L24_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056366">
        <property type="entry name" value="Ribosomal_eL24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000988">
        <property type="entry name" value="Ribosomal_eL24-rel_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011017">
        <property type="entry name" value="TRASH_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10792">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10792:SF8">
        <property type="entry name" value="RIBOSOME BIOGENESIS PROTEIN RLP24-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01246">
        <property type="entry name" value="Ribosomal_L24e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00746">
        <property type="entry name" value="TRASH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57716">
        <property type="entry name" value="Glucocorticoid receptor-like (DNA-binding domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0690">Ribosome biogenesis</keyword>
    <feature type="domain" description="TRASH" evidence="3">
        <location>
            <begin position="6"/>
            <end position="44"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005647"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00746"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OBZ90799.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="159" mass="19010" checksum="F76DEEFDA3CE98AF" modified="2016-11-30" version="1">MHITRCYFCSGPCYPGHGTMFVRNDSKTFRFCRSKCHKNFKMKRNPRKVRWTKAFRKASGKEMVIDSTFEFEKRRNVPVRYDRNMMATTIKAMKRVQEIRAKRERAFYKNRMAGNKDKEKEDDIRVVNQNIELAPLEAKKRLQAIKSEKAKAENMEMEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NQ86</accession>
    <name>A0A1C7NQ86_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Protein OPI10</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">A0J61_00659</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the OPI10 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000016">
        <property type="protein sequence ID" value="OBZ91272.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NQ86"/>
    <dbReference type="FunCoup" id="A0A1C7NQ86">
        <property type="interactions" value="445"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NQ86"/>
    <dbReference type="InParanoid" id="A0A1C7NQ86"/>
    <dbReference type="OrthoDB" id="10248398at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005635">
        <property type="term" value="C:nuclear envelope"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061608">
        <property type="term" value="F:nuclear import signal receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006606">
        <property type="term" value="P:protein import into nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048364">
        <property type="entry name" value="Hikeshi-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008493">
        <property type="entry name" value="Hikeshi-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031318">
        <property type="entry name" value="OPI10"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12925">
        <property type="entry name" value="HIKESHI FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12925:SF0">
        <property type="entry name" value="PROTEIN HIKESHI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21057">
        <property type="entry name" value="Hikeshi-like_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05603">
        <property type="entry name" value="Hikeshi-like_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Hikeshi-like N-terminal" evidence="2">
        <location>
            <begin position="5"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="domain" description="Hikeshi-like C-terminal" evidence="3">
        <location>
            <begin position="133"/>
            <end position="197"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006623"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF05603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF21057"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OBZ91272.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="202" mass="22311" checksum="B535211EED863524" modified="2016-11-30" version="1">MFGCIAAGRLVQTNLQQVDVNKYVFELNDAQNINHIVVFLLGTIPFEPGYAATVHLLWPNKEWQMLGGLSNEKPSAIFRLKTKESTVNPSQISTPATLGISIEPIQVVEQEIATLQSANMTTSLVKANANVSQVGQMAGKVLENLYNYVTSFTVHNIPVNAIPLGQLTENGYLPLKTFQTWYDNLSRKLATNPNYLDTEKSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NQE1</accession>
    <name>A0A1C7NQE1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Ubiquitin carboxyl-terminal hydrolase</fullName>
            <ecNumber evidence="9">3.4.19.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">ubp21_0</name>
        <name evidence="13" type="ORF">A0J61_00815</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).</text>
            <dbReference type="EC" id="3.4.19.12"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 9">Belongs to the peptidase C19 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.19.12" evidence="9"/>
    <dbReference type="EMBL" id="LUGH01000021">
        <property type="protein sequence ID" value="OBZ91139.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NQE1"/>
    <dbReference type="STRING" id="101091.A0A1C7NQE1"/>
    <dbReference type="InParanoid" id="A0A1C7NQE1"/>
    <dbReference type="OrthoDB" id="289038at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004843">
        <property type="term" value="F:cysteine-type deubiquitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140492">
        <property type="term" value="F:metal-dependent deubiquitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016579">
        <property type="term" value="P:protein deubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031647">
        <property type="term" value="P:regulation of protein stability"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02659">
        <property type="entry name" value="peptidase_C19C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.70.10:FF:000005">
        <property type="entry name" value="Ubiquitin carboxyl-terminal hydrolase 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.210.10">
        <property type="entry name" value="Apoptosis, Tumor Necrosis Factor Receptor Associated Protein 2, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.70.10">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002083">
        <property type="entry name" value="MATH/TRAF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050164">
        <property type="entry name" value="Peptidase_C19"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001394">
        <property type="entry name" value="Peptidase_C19_UCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008974">
        <property type="entry name" value="TRAF-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028889">
        <property type="entry name" value="USP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018200">
        <property type="entry name" value="USP_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24006">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24006:SF644">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22486">
        <property type="entry name" value="MATH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00443">
        <property type="entry name" value="UCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00061">
        <property type="entry name" value="MATH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49599">
        <property type="entry name" value="TRAF domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50144">
        <property type="entry name" value="MATH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00972">
        <property type="entry name" value="USP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00973">
        <property type="entry name" value="USP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50235">
        <property type="entry name" value="USP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9 13" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="4 9" id="KW-0645">Protease</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 9" id="KW-0788">Thiol protease</keyword>
    <keyword evidence="5 9" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="MATH" evidence="11">
        <location>
            <begin position="37"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="domain" description="USP" evidence="12">
        <location>
            <begin position="190"/>
            <end position="518"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="473"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="478"/>
            <end position="489"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU366025"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="OBZ91139.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="597" mass="69249" checksum="A48B4B56969502AF" modified="2016-11-30" version="1">MKSTETTKAKSAFSIYEHDKVLPHVLPIHKELEEIDFQVHHWEIDNWNSLEQRSHGPIFEAAGLQWRILLFPKGNSQHDMVSIYLEVVTDSKKDKKNWSVCGEFAVIISNPDDPKHFHASHAHHRFCGEEVDWGFTRFYDIKQLIGGKEPYVNHEHKTTISIFLRVVKDETGVLWHNLINYDSRKETGYVGIRNQGATCYMNSLIQSLYFTNSFRKAVYQIPTEREDPTNSVALALQRCFYNLQYSDESVGTTELTKSFGWDSADAFMQHDVQEFSRVLQDNLELKMKGTRVEGAVTDIFMGKMKSYIKCLHIEYESSRVEDFYDIQLNVKGCKSLFESFQRYVEPEILDGDNKYMAEGHGLQDACKGVSFESFPPVLHLQLKRFEYDMQRDTMVKINDHHVFPDQINLNEFCSTPSENPADNNYILHGVLVHSGDVDNGHYFALLKPERNGKWFRFDDDRVTPVTLREVFEDNYGDDPLRQQDDKTTAEHPNLTPPYTSLQTLKRFTNAYMLVYFQESQLDSILGQIDEKEIPKHLAPSLKDNAKALKEDVLNNLISQPQLNKIQSNNNHTNTPPLKQTHIRLKKMEKSDKKCLMM</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NQM5</accession>
    <name>A0A1C7NQM5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Exportin-7</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">XPO7_0</name>
        <name evidence="9" type="ORF">A0J61_00749</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the exportin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000018">
        <property type="protein sequence ID" value="OBZ91209.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NQM5"/>
    <dbReference type="InParanoid" id="A0A1C7NQM5"/>
    <dbReference type="OrthoDB" id="244158at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005643">
        <property type="term" value="C:nuclear pore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005049">
        <property type="term" value="F:nuclear export signal receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006611">
        <property type="term" value="P:protein export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057947">
        <property type="entry name" value="TPR_XPO7/RBP17"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044189">
        <property type="entry name" value="XPO4/7-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12596">
        <property type="entry name" value="EXPORTIN 4,7-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12596:SF2">
        <property type="entry name" value="EXPORTIN-7 ISOFORM X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25795">
        <property type="entry name" value="TPR_XPO7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Exportin-7/Ran-binding protein 17 TPR repeats" evidence="8">
        <location>
            <begin position="441"/>
            <end position="686"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF25795"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OBZ91209.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="1124" mass="129317" checksum="7F60CFE7C26244F7" modified="2016-11-30" version="1">MTSAIAQQDRIGYFSTLCQELYNPKTTSERDQVQKILEASFPTFSTETNKLDLGQTPSFGIQTPTDTANALRILLENSPNPYVQTFSFSRLKQLVIAQFSLFDHDTKLQLRAFLLEYAYLHTDLQPFVMAQLASVFALLTRFGWLDHEEYQHVYEDMTQFLRASASHRIVGLQILAVVIQDINSVTLPKYSAKFRKAAAGLRDTQLLKIFENGFEILRGTLTRSIPFDQGKTKEVALDLLLKCLSFDFAGTSLDESNDDLGNVQIPSSWRAIYERPEFVSTFFEAYKQLPSSLATKAMDCLVQIAATRKALFSGEDERSKFVTSIMHGVQDIILTSQHLNDSDCYNGFCRLLQRFRTTAPLNEMAEKQGYMEWIELVADFTLKAFQTYTPTNTCFHLLSFWSRIVQSMTYYQQLEKAVVQKLQSITIELTKRFISAYVDSVSARIEELLDDPLDDEDTLVESLTMLGQVARCQYEQSCAALIEIFDPIATHYEELISQATMGAISGESLKEAIEVFEAKFAWMVYVMACFVGNRPPYANSDESDQVDGELVTKVLQMMEINQNLSQTNPSFQSQKFELALLYFFSQFRKAYVGESTGNAVYQKLNQVFGLEEEGDMLNLIMRKIINNLQVWGESELIILKTLELFNELASGYSALRNLRKIESTTMIMQNHLSSEFGFFNHDKHRHSRMLYYQVLCKILFAEDSSEQEFYEFMKPFEVRLESLCALNTIEAYQQPQVQNALVAIFRDLRGFIEPIQSRKNYLLFFHWFYPDYMPVLIKGVQALSPDPSTHVLLKFLVEFVSNKSQRLSLDVSSANGVLLFRDASQILTIFGQHITSRHITDESKKYPLKYKGMTACFNILARCLGGKYINFGIFWLYQDKAIRDAFSTMYQLMLNIPLDDLMNFPKLSKAFFDMMDEFSAEQMMLDADMPPEAFLYLLEACELGIESTDSWVRTHACSTIYNICSFLIQQTQKAEIRRDAKGQKNKPVQGLWFLNYFEQFPQVLPKLLSSLFGMILFDDNSDQWQLSRPLYTLVLLQRDVSDTDGLFIETRTKKKNEXKFASKYTNQVILQQLPERREFVTKALGNLMEGSTWTLSSKDRERFSQQMASLKRELNTHQITLIPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NQN1</accession>
    <name>A0A1C7NQN1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 8">Mediator of RNA polymerase II transcription subunit 17</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7 8">Mediator complex subunit 17</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="primary">srb4_1</name>
        <name evidence="8" type="synonym">MED17</name>
        <name evidence="10" type="ORF">A0J61_00547</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Component of the Mediator complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 8">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the Mediator complex subunit 17 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000012">
        <property type="protein sequence ID" value="OBZ91402.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NQN1"/>
    <dbReference type="STRING" id="101091.A0A1C7NQN1"/>
    <dbReference type="InParanoid" id="A0A1C7NQN1"/>
    <dbReference type="OrthoDB" id="10251234at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070847">
        <property type="term" value="C:core mediator complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016592">
        <property type="term" value="C:mediator complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003712">
        <property type="term" value="F:transcription coregulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019313">
        <property type="entry name" value="Mediator_Med17"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13114">
        <property type="entry name" value="MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13114:SF7">
        <property type="entry name" value="MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10156">
        <property type="entry name" value="Med17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0010">Activator</keyword>
    <keyword evidence="6 8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0804">Transcription</keyword>
    <keyword evidence="4 8" id="KW-0805">Transcription regulation</keyword>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="70"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="489"/>
            <end position="512"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="70"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="489"/>
            <end position="500"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005635"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00019610"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00032014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU364140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OBZ91402.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="819" mass="89687" checksum="1E8771BAC8996510" modified="2016-11-30" version="1">MTEQPPAKKIKISLEPFIDNHVADITNLGQEILKTEVSLPEKLMHSVDRIWFERGEWKDITETSLKKAIEEQQDKKQEDQDENKQDAPSLPNSMPSTAQPPPPPGFDIIKLRESVINKLFHAKSEIDVALDVINILAASNRASATTKDLVLPAGSLTATYVTKPKQTMKAQLESTQLNLGLKRTKQKQAADFLKNSAATLKGLVEKEQVFWNEALDLRRNNWQMFPSNQLGNVNTGSSFFVQYGFSEVGSDFNEASMGELKRGGDTTDNNALQLSLPHANSRQVVVSISQSQMGQLKIGRNRFSEGILGMIESDETEKKDTTCSPLFSNNTIHSEVQAQLGDAHATVFDAELFSDILAEAQALSSNVRFPDDEIVINIDGHIDLSIRKEPVENRLASFDSSVSPQSVIISRSINLAFRLLLLQHQRYNAWKQKAKYLSTNPKIHPMLAQHDASLLISSAAAQAAAQAAQISQTNANPSSQSMIANSPVNSATGSVTNGIQSPKVGQPSTTSNVNPAISTTTPNVVNATVGPSNTVGSGNVTGAVGSSTSVANVASAAMRAQTRSPNQITPRALPQHIPVLLPILSLTRFWVQFDRVRQVIHHLISPLCASIAIAAHFKCELMSMPSSSLPKKHLYDTYPGYTEVALSLGISLFKGPSLKFGLNQSGSISVCLPQTTVVLQNVSEFESFLSREIKVICLQTVCSIANDIMGRHADYMKAVGTTNKQRFLWQVDKVDEAIHGSVWSSQGADHVWRNITVSMKHLGTSYSVQFQLDRTHLLEEKTYTVELGKHASNELAMGFREKVFALVKLIIDDAIMTLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NQP3</accession>
    <name>A0A1C7NQP3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">GATA-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">A0J61_00507</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000011">
        <property type="protein sequence ID" value="OBZ91437.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NQP3"/>
    <dbReference type="STRING" id="101091.A0A1C7NQP3"/>
    <dbReference type="InParanoid" id="A0A1C7NQP3"/>
    <dbReference type="OrthoDB" id="2162994at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00202">
        <property type="entry name" value="ZnF_GATA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.50.10">
        <property type="entry name" value="Erythroid Transcription Factor GATA-1, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051140">
        <property type="entry name" value="GATA_TF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000679">
        <property type="entry name" value="Znf_GATA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013088">
        <property type="entry name" value="Znf_NHR/GATA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45658">
        <property type="entry name" value="GATA TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00320">
        <property type="entry name" value="GATA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00401">
        <property type="entry name" value="ZnF_GATA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57716">
        <property type="entry name" value="Glucocorticoid receptor-like (DNA-binding domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00344">
        <property type="entry name" value="GATA_ZN_FINGER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50114">
        <property type="entry name" value="GATA_ZN_FINGER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="GATA-type" evidence="5">
        <location>
            <begin position="357"/>
            <end position="388"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00094"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50114"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OBZ91437.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="399" mass="46058" checksum="E15B8C080388BEFE" modified="2016-11-30" version="1">MSCYWALLSLETFKYIYLPSNVRDILMTSDVSMGDIPFTQSLFDYIHPEESYLATNDLSNFVRRKTLSGAVTRCRFLTIQSIIRQQKKIQKNSSSSNEAMDWAVTDLVMYNATDKIVLTFFHTLCIDATDHHFNCCGSPEIGSNEINYMKTVLRQYHTTSPLHPLCLFQIHDTLKQHPLLTYHSVKSNDQIETNFMRNVHSMIHEITLQEIKRRRRNDITNQPTCTQPAQSTTTQSIPPYDSCRVESIVIVYGHLTFSLIQVVPHCLDNQSKTILQPDLPFSFQNNPTSLLYHSSSPKQFISNQLNKTIVEGERISHSSPVISHNRGKSWININSRFQHETSFLPKIWRGRFGIHEKRCKNCDTSKSPEWRRGPNGHKTLCNACGLRYARLMAKHEKKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NR32</accession>
    <name>A0A1C7NR32_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Ubiquitin-conjugating enzyme E2 6</fullName>
            <ecNumber evidence="2">2.3.2.23</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12">E2 ubiquitin-conjugating enzyme 6</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="15" type="primary">UBC6</name>
        <name evidence="15" type="ORF">A0J61_02225</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.23" evidence="2"/>
    <dbReference type="EMBL" id="LUGH01000081">
        <property type="protein sequence ID" value="OBZ89714.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NR32"/>
    <dbReference type="FunCoup" id="A0A1C7NR32">
        <property type="interactions" value="799"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NR32"/>
    <dbReference type="InParanoid" id="A0A1C7NR32"/>
    <dbReference type="OrthoDB" id="1158011at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061631">
        <property type="term" value="F:ubiquitin conjugating enzyme activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036503">
        <property type="term" value="P:ERAD pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0180027">
        <property type="term" value="P:inner nuclear membrane-associated protein degradation pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006513">
        <property type="term" value="P:protein monoubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000209">
        <property type="term" value="P:protein polyubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd23799">
        <property type="entry name" value="UBCc_UBE2J"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.110.10:FF:000023">
        <property type="entry name" value="Ubiquitin-conjugating enzyme E2 J2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.110.10">
        <property type="entry name" value="Ubiquitin Conjugating Enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050113">
        <property type="entry name" value="Ub_conjugating_enzyme"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000608">
        <property type="entry name" value="UBC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016135">
        <property type="entry name" value="UBQ-conjugating_enzyme/RWD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24067">
        <property type="entry name" value="UBIQUITIN-CONJUGATING ENZYME E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00179">
        <property type="entry name" value="UQ_con"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00212">
        <property type="entry name" value="UBCc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54495">
        <property type="entry name" value="UBC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50127">
        <property type="entry name" value="UBC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="10 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 13" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="204"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="domain" description="UBC core" evidence="14">
        <location>
            <begin position="5"/>
            <end position="162"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004586"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012486"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00039885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00042181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="OBZ89714.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="229" mass="26010" checksum="FB3DC8D0AFE5BBA2" modified="2016-11-30" version="1">MATKGAYKRLTKEYMAIQKNPPPYIIAKPLESNILDWHYVITGPPDSPYEGGEYYGRITFPAEYPFKPPAIRMTTPSGRFQPDTRLCLSMSDFHPSSWNPSWSIATILNGLLSFMVSDEATTGSIKTGVNEKKIYAARSHLWNLKNPKFREVFPELCTINSNQLSNDSLLLKRTTSPKPLPTTEFNQQQPNDMTQTAMSRGKRWIFVFVVFVYLIISKLIARSTSTNMA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NRU2</accession>
    <name>A0A1C7NRU2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">4-hydroxy-4-methyl-2-oxoglutarate aldolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">YER010C</name>
        <name evidence="2" type="ORF">A0J61_00293</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000006">
        <property type="protein sequence ID" value="OBZ91649.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NRU2"/>
    <dbReference type="STRING" id="101091.A0A1C7NRU2"/>
    <dbReference type="InParanoid" id="A0A1C7NRU2"/>
    <dbReference type="OrthoDB" id="1476984at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047443">
        <property type="term" value="F:4-hydroxy-4-methyl-2-oxoglutarate aldolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008948">
        <property type="term" value="F:oxaloacetate decarboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd16841">
        <property type="entry name" value="RraA_family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.30.40">
        <property type="entry name" value="Ribonuclease E inhibitor RraA/RraA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005493">
        <property type="entry name" value="RraA/RraA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036704">
        <property type="entry name" value="RraA/RraA-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33254">
        <property type="entry name" value="4-HYDROXY-4-METHYL-2-OXOGLUTARATE ALDOLASE 3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33254:SF4">
        <property type="entry name" value="4-HYDROXY-4-METHYL-2-OXOGLUTARATE ALDOLASE 3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03737">
        <property type="entry name" value="RraA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89562">
        <property type="entry name" value="RraA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0460">Magnesium</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="96"/>
            <end position="99"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="118"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="119"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR605493-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ91649.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="221" mass="24209" checksum="D75E4EBAA0F4B136" modified="2016-11-30" version="1">MSNLEQLKKFSSCEVADALIKLGKGPWAGYIPDIELWSPQYCQGDTRIVGPAFTVKMVDKYDTTSPTPSEHFADAAHEGSVVVISAPPDVKNAVWGGLMSARAKSKGVQGVVIDGRVRDLNEHREMKFPVFARSHSILPQNAFVRPSEIQVPITLSQESSVIVQPGDIIIADIDGVVCVPRDLVEKVIQSCEKYVAIDDQCMEALKKGYGVKETFAKYRGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NS24</accession>
    <name>A0A1C7NS24_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Protein byr4</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_00053</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000001">
        <property type="protein sequence ID" value="OBZ91935.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NS24"/>
    <dbReference type="STRING" id="101091.A0A1C7NS24"/>
    <dbReference type="InParanoid" id="A0A1C7NS24"/>
    <dbReference type="OrthoDB" id="19159at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990334">
        <property type="term" value="C:Bfa1-Bub2 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044732">
        <property type="term" value="C:mitotic spindle pole body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001100">
        <property type="term" value="P:negative regulation of exit from mitosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034586">
        <property type="entry name" value="Bfa1/Byr4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35140">
        <property type="entry name" value="MITOTIC CHECK POINT PROTEIN BFA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35140:SF1">
        <property type="entry name" value="MITOTIC CHECK POINT PROTEIN BFA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="277"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="325"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="384"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="543"/>
            <end position="562"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="284"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="384"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="543"/>
            <end position="552"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ91935.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="640" mass="73519" checksum="EE9F5614543A6B50" modified="2016-11-30" version="1">MTSREDDWEVDINLGSSTGRNVFQRKGVFNYEPDKELALACERYQYAIPNIYSDGEDDADSSIASSSIISGQLSELSLINLDNFMYDEEPTLTAETILPDNQNKFPGTIRKLRARHKENQDHDDWNDDIEIPSRNIQFSLTKKKSYEQLLDVFDDNDSIGPSVSQRGSPCSFEVQTKEHTQPSRYRYVEQDEDSFSELDFPENMALLPKKLNEKKSIAYDRLSPASHVTAVDSNKSTAKKSSLLTKVKRENDNDDFLEGLEIKEKVFKASISASKLPIPQPQRSTSTNKTKSGTSHFVSRLARPTQTRPNVVDQAAKRTPFQSAIPQVPQQRQPPPIRRNILSNPQTTLPRETELPTRHTAYTYKQPPQRKQFSLRNNLQLMNNNTSLPRNAESSPSEKRGANGSTLIAKPKTKIPISYCSRLDNIDNLNDLQPMRSRTTKMEPKDFSRNERINIDHSWKKSGQPSKIKLIQPNEQNLRKEYHGMKYDFRTHSWKGNESGLIDFPEKPAVKKHPKLVLLTSKQRTPSKYTAIMSDNMIFKPESQSWVSPSGKENNDLDGIEDLPEDLRPVSKRMPKHSQYRNKMTEFKLSIEIKRQMMAEQQQHENLIKQWPLNEEESYMTSTAGHKVPVSKYFLFTQSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NSA4</accession>
    <name>A0A1C7NSA4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Small nuclear ribonucleoprotein Sm D2</fullName>
            <shortName evidence="10">Sm-D2</shortName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">snRNP core protein D2</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="primary">smd2</name>
        <name evidence="13" type="ORF">A0J61_00039</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
            <location evidence="2">Cytosol</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1 10">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the snRNP core protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000001">
        <property type="protein sequence ID" value="OBZ91948.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NSA4"/>
    <dbReference type="FunCoup" id="A0A1C7NSA4">
        <property type="interactions" value="908"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NSA4"/>
    <dbReference type="InParanoid" id="A0A1C7NSA4"/>
    <dbReference type="OrthoDB" id="437526at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071014">
        <property type="term" value="C:post-mRNA release spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000974">
        <property type="term" value="C:Prp19 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005685">
        <property type="term" value="C:U1 snRNP"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005689">
        <property type="term" value="C:U12-type spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005686">
        <property type="term" value="C:U2 snRNP"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071004">
        <property type="term" value="C:U2-type prespliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005687">
        <property type="term" value="C:U4 snRNP"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046540">
        <property type="term" value="C:U4/U6 x U5 tri-snRNP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005682">
        <property type="term" value="C:U5 snRNP"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036261">
        <property type="term" value="P:7-methylguanosine cap hypermethylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd01720">
        <property type="entry name" value="Sm_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.30.100:FF:000069">
        <property type="entry name" value="Small nuclear ribonucleoprotein Sm D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010920">
        <property type="entry name" value="LSM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047575">
        <property type="entry name" value="Sm"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027248">
        <property type="entry name" value="Sm_D2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001163">
        <property type="entry name" value="Sm_dom_euk/arc"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12777">
        <property type="entry name" value="SMALL NUCLEAR RIBONUCLEOPROTEIN SM D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01423">
        <property type="entry name" value="LSM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00651">
        <property type="entry name" value="Sm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50182">
        <property type="entry name" value="Sm-like ribonucleoproteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52002">
        <property type="entry name" value="SM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 10" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="7 10" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="8 10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9 10 13" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="6" id="KW-0747">Spliceosome</keyword>
    <feature type="domain" description="Sm" evidence="12">
        <location>
            <begin position="30"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="8"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004514"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU365051"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS52002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="OBZ91948.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="114" mass="13115" checksum="5C3DC67AC452A86C" modified="2016-11-30" version="1">MSSAINKPRSEMTEEELRQQEELEFNTGPLSVLQQSVKNNNQILISCRNNHKLLARVKAFDRHCNMVLENVKEMWTETPRSGKGSKAKPVNKDRFVSKMFLRGDTVVLVLRNTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NT71</accession>
    <name>A0A1C7NT71_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Vacuolar protein sorting-associated protein 53</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">VPS53</name>
        <name evidence="11" type="ORF">A0J61_01273</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Endosome membrane</location>
            <topology evidence="2">Peripheral membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Golgi apparatus</location>
            <location evidence="1">trans-Golgi network membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the VPS53 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000038">
        <property type="protein sequence ID" value="OBZ90694.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NT71"/>
    <dbReference type="FunCoup" id="A0A1C7NT71">
        <property type="interactions" value="542"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NT71"/>
    <dbReference type="InParanoid" id="A0A1C7NT71"/>
    <dbReference type="OrthoDB" id="10261632at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010008">
        <property type="term" value="C:endosome membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000938">
        <property type="term" value="C:GARP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042147">
        <property type="term" value="P:retrograde transport, endosome to Golgi"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.357.110">
        <property type="entry name" value="Vacuolar protein sorting-associated protein 53, C-terminus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039766">
        <property type="entry name" value="Vps53"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031745">
        <property type="entry name" value="Vps53_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038260">
        <property type="entry name" value="Vps53_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007234">
        <property type="entry name" value="Vps53_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12820:SF0">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 53 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12820">
        <property type="entry name" value="VACUOLAR SORTING PROTEIN 53"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16854">
        <property type="entry name" value="VPS53_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04100">
        <property type="entry name" value="Vps53_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0967">Endosome</keyword>
    <keyword evidence="5" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Vps53 N-terminal" evidence="9">
        <location>
            <begin position="30"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="domain" description="Vps53 C-terminal" evidence="10">
        <location>
            <begin position="613"/>
            <end position="698"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="771"/>
            <end position="790"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="54"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="771"/>
            <end position="786"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008628"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022753"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF04100"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF16854"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="OBZ90694.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="817" mass="92778" checksum="6290A250262AF066" modified="2016-11-30" version="1">MSTNKAKVSRQLEAQALAILNAKSFLDSPEFDAAEYLNRLFPTEKSLASVDGVLTKLQVKMTEMSREAERLTDTQYDKDASEGNKDLQKANQAIQELFKRIQDIKFKAAQSESMVQEITQDVKSLDYAKRHLTHSVTVLKRLQMLVTAVDQLEVMSRNKQYKESAQLLQAVLQLMQHFRSYKSVPQISQLSDRIASLKKELENCVIHELENGFNQEGQLVGQSWILHDACLVADVLGDETKDRIVTRYVDLQLVSYRQIFRPMEEVSQLDNVSRRYAFLKRILKTCDDEHADIFPSSWAVSAKLCDRFCEHTRLSIEIVMKNELPDVKELLKALQLTIEFESQLTKRYEKFGNSALFDFEKKISAAFQPYLYIYINAEDATIASMIDSYVQSDAKSESEDDGSMAVLPSSTDLFYFYRETLAQTSKFSTGKALFDLYLLFSKHLNSYCNQILLGGLTKNEKQAVSPVHFRFASLALNTAEYCHMTSSQLEEKLKEKIDNEYVNQIDFQAVKDSFMKAISVCIDTIIKNLEQSIDSQMSQMTRLPWSTMDTVGDQSDYVSQILDIIKNNVGIVGKVVVNRRYYRTFSDRFAELFVTKFLVQIFKCKMISEIGAEQLLLDTHSIKTLLLEIPSIGASEGIITVPSSYSRIVNKGITKIEAILKTVMSPIEPSEGYVENYFLLIGDKNLNNFTRLLELKGVRKPEQNVLIDMFYKRLSQHDDLSDNSKLLPSESLVTSNPISSSSVATIPSSITTSLTTMASTAASNFNINNTNGTHHVLSPTTSSPTEGTRGRLNENFRKLMMTGMAFRKDLQERREHT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7LJT2</accession>
    <name>A0A1C7LJT2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">CENP-B protein 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">cbh2_1</name>
        <name evidence="2" type="ORF">A0J61_11964</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01002781">
        <property type="protein sequence ID" value="OBZ63751.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7LJT2"/>
    <dbReference type="FunCoup" id="A0A1C7LJT2">
        <property type="interactions" value="216"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7LJT2"/>
    <dbReference type="InParanoid" id="A0A1C7LJT2"/>
    <dbReference type="OrthoDB" id="2350305at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050863">
        <property type="entry name" value="CenT-Element_Derived"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004875">
        <property type="entry name" value="DDE_SF_endonuclease_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19303:SF73">
        <property type="entry name" value="PROTEIN PDC2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19303">
        <property type="entry name" value="TRANSPOSON"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03184">
        <property type="entry name" value="DDE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DDE-1" evidence="1">
        <location>
            <begin position="197"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="300"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ63751.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="300" mass="34415" checksum="7547EFAB2A1E2CFF" modified="2016-11-30" version="1" fragment="single">MSNKRVRLTVDQKIQILVENLKGKLDTVEPGKCAMEKFALSKPLAQQTISKIISSADELYSNISLKTSRKSAKSPKHPQLDAEVKKYVEDMNNLNQHINRESVIKYVRMVALTKYKIPQGEINFSDGWLPLVFKRIGVKSRLTHGESTSEQLKKIAELLRPYNSQNILNFDETGLYYNRPLRRTINSQPVGGMKNSKEHLTFGLLCNADGSYRGHPIVIVKHKYPTGYKDYPKLHAMTAIGKPHYIEYHCSPNAWMKKEIFEGYVKRLDRAFGREKRKVAILLDNAFVHKVGYQPENILL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7LLA3</accession>
    <name>A0A1C7LLA3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_11961</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01002775">
        <property type="protein sequence ID" value="OBZ63977.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7LLA3"/>
    <dbReference type="STRING" id="101091.A0A1C7LLA3"/>
    <dbReference type="InParanoid" id="A0A1C7LLA3"/>
    <dbReference type="OrthoDB" id="2265092at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="184"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ63977.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="207" mass="22843" checksum="B8149093DB88AD62" modified="2016-11-30" version="1" fragment="single">AVCDRVVVVQEPIIRVTSGQSITLEAKGTDTSLRMNFMVSNNNFAMMYYFIRFIKLQSSRRVIGALRVSAYTFDDASRAFASVRVGMQSVAPIWEINFRGNTTGFGIADGCVPVDKENAPPNQEYAKLKSIIFKYGLYDDLVEAELAAPNASPILLEQRRTRDARSSRSARRGTIQVRTFDESIFASPPDNEDPALGGGSPLTAMMD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-06-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MTN4</accession>
    <name>A0A1C7MTN4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_11824</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01002541">
        <property type="protein sequence ID" value="OBZ80127.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="InParanoid" id="A0A1C7MTN4"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="126"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ80127.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="126" mass="13715" checksum="6ED5B8295895646F" modified="2016-11-30" version="1" fragment="single">MGAGFVASGTWVSGRSEERGLSWEGAIRVKVFLVNTVGIRGVTGLPTLGLVAGMVLVPEVVIDEDDEDDEDDDRRRRLERYEIYFGVCKEEEVWVSTXVVGASGVGEGGVVGVVIIDFVKIKQVFR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MUR4</accession>
    <name>A0A1C7MUR4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_11368</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001957">
        <property type="protein sequence ID" value="OBZ80583.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MUR4"/>
    <dbReference type="InParanoid" id="A0A1C7MUR4"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="65"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="80"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="94"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="148"/>
            <end position="157"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ80583.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="157" mass="18597" checksum="922C6AD1F87F5D0A" modified="2016-11-30" version="1">MIKRCVNDNVNWQEWTYKNIPAKRKLRAYHQSRKFAGISDIPTYRCDSYWLEKKLIEKFYRHKSKKTIKKNKTSIGCNGKGKEKEENENRARQEDDDEQQQQLQEDGEDDLSWDSDLEQLAGYSDEDVEGQLFGEGNEYEGSSSQPPAKRRRYDTFN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MUS2</accession>
    <name>A0A1C7MUS2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_11401</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001991">
        <property type="protein sequence ID" value="OBZ80550.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MUS2"/>
    <dbReference type="InParanoid" id="A0A1C7MUS2"/>
    <dbReference type="OrthoDB" id="2306559at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ80550.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="289" mass="33323" checksum="8FB947272F0C6896" modified="2016-11-30" version="1" fragment="single">PMTTMLSAADAACSIYGLEITLENQLSALQQHKDAGLELCYVSQWRSHHCSRHVDKEIYIPNDTVTSDGLSAWMSKDGTWGTNIRRQSNRQKRKRGRLLNVVKKVYRGNTWEKYSSYFDWILLGMIFQISLVKSPMATKCTIGYVRKSNTNEPDITKKKLINLQIYKRKTKLLCEDVFVSYNTSLNDPIAERDVTTPLYTFDDCSGNTQDLITKITKSARQIRLVVVDYTGFSTNPGGIRLFISLNKSVREVVVDVGHKVEVYSRYDLLKNIKILNKFQCWRECIKRLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MV24</accession>
    <name>A0A1C7MV24_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Reverse transcriptase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_11230</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001806">
        <property type="protein sequence ID" value="OBZ80721.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7MV24"/>
    <dbReference type="InParanoid" id="A0A1C7MV24"/>
    <dbReference type="OrthoDB" id="2245799at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01647">
        <property type="entry name" value="RT_LTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.10.10">
        <property type="entry name" value="HIV Type 1 Reverse Transcriptase, subunit A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043502">
        <property type="entry name" value="DNA/RNA_pol_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000477">
        <property type="entry name" value="RT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051320">
        <property type="entry name" value="Viral_Replic_Matur_Polypro"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33064">
        <property type="entry name" value="POL PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33064:SF37">
        <property type="entry name" value="RIBONUCLEASE H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00078">
        <property type="entry name" value="RVT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56672">
        <property type="entry name" value="DNA/RNA polymerases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50878">
        <property type="entry name" value="RT_POL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Reverse transcriptase" evidence="1">
        <location>
            <begin position="55"/>
            <end position="240"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ80721.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="316" mass="36047" checksum="18AC97C87DB93B35" modified="2016-11-30" version="1">MKENKRIKAGTFCSLTESIVSIPVKPDVNYYTRQYPLPYHGIPDISKQLKEWLDAGIVMKRKASGSYNLPILAISKKDDDGKPTKIRVCMDVRKINLHIPDNIDQFAVPNVQTILEKVAANGNVFTKLDLKSAYHSFRIHEDSHEVLSFTFMNQTYSWVGCPFGLKMITSTFCRVMSVILQDLDGVECYVDDICIYFRDPKQHATLVEKTIRRLTRYNLRIDFGKSVFXKTSINMLGAVIGPQVTKIDCRRLSNIDEWKPCENAAQVRALMGDTTYMRAYVPMISKITAPLDALRHDPNVMKHWASLHTKSLEAVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MV61</accession>
    <name>A0A1C7MV61_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_11200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UPF0047 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001769">
        <property type="protein sequence ID" value="OBZ80751.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MV61"/>
    <dbReference type="FunCoup" id="A0A1C7MV61">
        <property type="interactions" value="106"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7MV61"/>
    <dbReference type="InParanoid" id="A0A1C7MV61"/>
    <dbReference type="OrthoDB" id="10255963at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.460">
        <property type="entry name" value="YjbQ-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001602">
        <property type="entry name" value="UPF0047_YjbQ-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035917">
        <property type="entry name" value="YjbQ-like_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00149">
        <property type="entry name" value="TIGR00149_YjbQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30615">
        <property type="entry name" value="UNCHARACTERIZED PROTEIN YJBQ-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30615:SF8">
        <property type="entry name" value="UPF0047 PROTEIN C4A8.02C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01894">
        <property type="entry name" value="YjbQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004681">
        <property type="entry name" value="UCP004681"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111038">
        <property type="entry name" value="YjbQ-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01314">
        <property type="entry name" value="UPF0047"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ80751.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="141" mass="15905" checksum="3AC66A5AC8123C59" modified="2016-11-30" version="1">MSWAQREIRIKERSRGCHLVHSEIVNQLPELKSFKVGIANFFLQHTSASLMINENFDSDVQKDMEMGLNKIVPEDFPYIHTAEGPDDMPGHLKSGIVGVSLNIPITNGKLNLGTWQGIYLCEHRNYGGARRVVVTMQGQQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MVN3</accession>
    <name>A0A1C7MVN3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Dyskerin-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_11068</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001643">
        <property type="protein sequence ID" value="OBZ80883.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MVN3"/>
    <dbReference type="STRING" id="101091.A0A1C7MVN3"/>
    <dbReference type="InParanoid" id="A0A1C7MVN3"/>
    <dbReference type="OrthoDB" id="10250002at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031429">
        <property type="term" value="C:box H/ACA snoRNP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009982">
        <property type="term" value="F:pseudouridine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000495">
        <property type="term" value="P:box H/ACA sno(s)RNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990481">
        <property type="term" value="P:mRNA pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031118">
        <property type="term" value="P:rRNA pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031120">
        <property type="term" value="P:snRNA pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.130.10">
        <property type="entry name" value="PUA domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012960">
        <property type="entry name" value="Dyskerin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036974">
        <property type="entry name" value="PUA_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004802">
        <property type="entry name" value="tRNA_PsdUridine_synth_B_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23127">
        <property type="entry name" value="CENTROMERE/MICROTUBULE BINDING PROTEIN CBF5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23127:SF0">
        <property type="entry name" value="H_ACA RIBONUCLEOPROTEIN COMPLEX SUBUNIT DKC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08068">
        <property type="entry name" value="DKCLD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01136">
        <property type="entry name" value="DKCLD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Dyskerin-like" evidence="1">
        <location>
            <begin position="17"/>
            <end position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM01136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ80883.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="66" mass="7372" checksum="558DA7D713BD31A6" modified="2016-11-30" version="1">MADNSVIKPTASAPAIDTSNWPLLLKNYDQLNVRTGHYTPIPSGCSPLKRPLDEYVRYGKKNLDKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MVQ0</accession>
    <name>A0A1C7MVQ0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_10966</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001546">
        <property type="protein sequence ID" value="OBZ80985.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MVQ0"/>
    <dbReference type="STRING" id="101091.A0A1C7MVQ0"/>
    <dbReference type="InParanoid" id="A0A1C7MVQ0"/>
    <dbReference type="OrthoDB" id="10670385at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="146"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="436"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="549"/>
            <end position="598"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="65"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="111"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="152"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="178"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="232"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="288"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="329"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="440"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="549"/>
            <end position="564"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="598"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ80985.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="598" mass="65200" checksum="DFDCAC40A61D4C56" modified="2016-11-30" version="1" fragment="single">MEPVENNAKKPKVPDLLQSDKPIAPVGVSTVTTSAEITPSKLRSVPIPQPLILKRRASRSSISSTDEKTPFEHASHDPISPIDYRKLSEGECPSPVGIDFAEPHRSPPPHSSSTSSSFSPRYSSPPAGSGGKYMVRSKRASWIDGSSCIYDSSTPSTPSSKPIIPPLGVPKQHSIPATVTSSSPVIGSPVVPTTVSPLMSSSLPQHPHISSQSDDSSHKTGSLFKLREDRQQQQQLQQQQQQQQQLQQYHIPPKRESPIETVAPPSSMMDSLYVASKHRKLSEELDDIPSHDEKKRSHSIHERKGIIADTNSIHEEAYSPISSPHRSKAPSLPAPTASSSSGPKSASSSPLIAHATTSTPHTPHQKARRRSSMSMLRNIPSAELAHIVSGNSPNPVLKTPDLSAQHSLTMAPEEEFEAYGEGVPVYQNSLHSLLRKQLSNKRSSTSSSNSSSNSNHQRPSRRSMIDIRPLEADKDVVEMNLDAGPIDIHDQQQSFPMDDHTLMNSPVYPAMLLNESDEIKSGDKQVDHKPALVPSFSPQSFNRASVSDVNNPWHQSTSQHTSPLQCMDYFSNEPMPSIASSANLQGRRRQPMPPSSSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MW19</accession>
    <name>A0A1C7MW19_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Reverse transcriptase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_10961</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001541">
        <property type="protein sequence ID" value="OBZ80992.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MW19"/>
    <dbReference type="InParanoid" id="A0A1C7MW19"/>
    <dbReference type="OrthoDB" id="5598377at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ80992.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="46" mass="5134" checksum="C5E081F4BFBE0D1A" modified="2016-11-30" version="1" fragment="single">MPNRLISDNGWLNHTLMTTLRASKSTDPQVAVLLDAEKAYDRVHPG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-06-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MW49</accession>
    <name>A0A1C7MW49_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_10907</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001504">
        <property type="protein sequence ID" value="OBZ81043.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MW49"/>
    <dbReference type="InParanoid" id="A0A1C7MW49"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ81043.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="56" mass="6272" checksum="EA68A2B50BBED904" modified="2016-11-30" version="1">MTSPSNNRNQTRQPYASISAIRSNQQHFDLLSTAPTDYAQAINQHYGYTQDVEAAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MWW5</accession>
    <name>A0A1C7MWW5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">CCHC-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_10640</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001286">
        <property type="protein sequence ID" value="OBZ81312.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7MWW5"/>
    <dbReference type="InParanoid" id="A0A1C7MWW5"/>
    <dbReference type="OrthoDB" id="2287232at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.60.10">
        <property type="entry name" value="Zinc finger, CCHC-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="289"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="18"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="44"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="96"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="303"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="326"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="356"/>
            <end position="378"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ81312.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="468" mass="51249" checksum="B5F5AC5672F197C8" modified="2016-11-30" version="1">MRHLIQKAYTNKYGYYAKPEKSQSVEESVDKPAAQAATTTELLDSSDDSEESQVEEATTEESEASATEDDEEPPARPQENKKRKTASVSSPVVSRKPRETNPKKELHEVCNGSEHLWSVSSNLRRDYSRVFAEIVVSPSKYSQFIQAGFQLKAQGNFSAFPSLSSSSEILKISLSGLPSHYGRRQGGLDQLRTDMVQNLKNFGSVVDRGLITNSTGVYTGNGYAVPEIKSSESSNSPPHSLLHLIDWSKLPGHRCHSPENALADCLLRRKATTCFHCNELGHISRVYPRKNSGVGKKRKTPVANVSSTAPLESSADSQSRQAVGPTSVSSTSLVRERSSSSQTSSPIIKEKRPPSSVLSNPSPTRQSQRIIERQSSPAPATLDLPVISQPIVKCNSCGLEGHARTNSRFCLKNPKLLTADXPINTPSMREEADIDIEMEDDLPEXQLPANHVFXADTXTSLXASHTHQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MWY3</accession>
    <name>A0A1C7MWY3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Serine-arginine protein 55</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">B52</name>
        <name evidence="9" type="ORF">A0J61_10630</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001280">
        <property type="protein sequence ID" value="OBZ81322.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MWY3"/>
    <dbReference type="STRING" id="101091.A0A1C7MWY3"/>
    <dbReference type="InParanoid" id="A0A1C7MWY3"/>
    <dbReference type="OrthoDB" id="1099063at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd12339">
        <property type="entry name" value="RRM2_SRSF1_4_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050374">
        <property type="entry name" value="RRT5_SRSF_SR"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23003">
        <property type="entry name" value="RNA RECOGNITION MOTIF RRM DOMAIN CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23003:SF62">
        <property type="entry name" value="SERINE_ARGININE (SR)-TYPE SHUTTLING MRNA BINDING PROTEIN NPL3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 6" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="8">
        <location>
            <begin position="15"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="72"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="72"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="89"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="119"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="159"/>
            <end position="180"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OBZ81322.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="208" mass="24649" checksum="091A9FB16A2294A8" modified="2016-11-30" version="1">MSRRRTERSEVRDTNRIIVKNIPSKTTWQDLKDFMRKAGRVTFADILKDRDGEGVVEFARRDDMKYALRELDNEKLNGSRVTLEEAGRSRRRSSRDRSRSPRRSRSRRDRSRTPESRSRSRSRSPARRDRGRSHSRSPSRSHSRTRSPTPSRSRSASRRRSDERDDEDKLHDVKPEKLETIEDASYVKQEDFPMRSRSRSRSSVDDKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MXR1</accession>
    <name>A0A1C7MXR1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_10339</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001124">
        <property type="protein sequence ID" value="OBZ81612.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MXR1"/>
    <dbReference type="InParanoid" id="A0A1C7MXR1"/>
    <dbReference type="OrthoDB" id="2431110at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46579:SF2">
        <property type="entry name" value="C2H2-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46579">
        <property type="entry name" value="F5/8 TYPE C DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ81612.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="165" mass="18754" checksum="78CBE6B4CEDF3BB2" modified="2016-11-30" version="1">MVVCWTSKYVVNGVTKPALLSKPVLHDMQKVLETKFLLPPSHAVSSIARKMTVGSGFSNMKADEWATWLLVLSPYLLDGKLSPTQYKNWMLFVSTARILLSPSLSVVELDEAHSNLQKFLKSIVSDYDDKTLITANCHYAMHVKETILDYSSAPNHWLFNFKRYN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MYC5</accession>
    <name>A0A1C7MYC5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">thioredoxin-dependent peroxiredoxin</fullName>
            <ecNumber evidence="2">1.11.1.24</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">Prdx1_0</name>
        <name evidence="12" type="ORF">A0J61_10138</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>a hydroperoxide + [thioredoxin]-dithiol = an alcohol + [thioredoxin]-disulfide + H2O</text>
            <dbReference type="Rhea" id="RHEA:62620"/>
            <dbReference type="Rhea" id="RHEA-COMP:10698"/>
            <dbReference type="Rhea" id="RHEA-COMP:10700"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:30879"/>
            <dbReference type="ChEBI" id="CHEBI:35924"/>
            <dbReference type="ChEBI" id="CHEBI:50058"/>
            <dbReference type="EC" id="1.11.1.24"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.11.1.24" evidence="2"/>
    <dbReference type="EMBL" id="LUGH01001048">
        <property type="protein sequence ID" value="OBZ81813.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MYC5"/>
    <dbReference type="FunCoup" id="A0A1C7MYC5">
        <property type="interactions" value="531"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7MYC5"/>
    <dbReference type="InParanoid" id="A0A1C7MYC5"/>
    <dbReference type="OrthoDB" id="185659at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008379">
        <property type="term" value="F:thioredoxin peroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045454">
        <property type="term" value="P:cell redox homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033554">
        <property type="term" value="P:cellular response to stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042744">
        <property type="term" value="P:hydrogen peroxide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006979">
        <property type="term" value="P:response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd03015">
        <property type="entry name" value="PRX_Typ2cys"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.30.10:FF:000003">
        <property type="entry name" value="Peroxiredoxin 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000866">
        <property type="entry name" value="AhpC/TSA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050217">
        <property type="entry name" value="Peroxiredoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024706">
        <property type="entry name" value="Peroxiredoxin_AhpC-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019479">
        <property type="entry name" value="Peroxiredoxin_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10681:SF171">
        <property type="entry name" value="PEROXIREDOXIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10681">
        <property type="entry name" value="THIOREDOXIN PEROXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10417">
        <property type="entry name" value="1-cysPrx_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00578">
        <property type="entry name" value="AhpC-TSA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000239">
        <property type="entry name" value="AHPC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 9" id="KW-0049">Antioxidant</keyword>
    <keyword evidence="6" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5 9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3 9" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="7 9" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin" evidence="11">
        <location>
            <begin position="3"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="active site" description="Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity" evidence="10">
        <location>
            <position position="48"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009796"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00049091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRNR" id="PIRNR000239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR000239-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="OBZ81813.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="195" mass="22070" checksum="6A7482173AE25809" modified="2016-11-30" version="1">MVAQVQKQAPKFEAKCVYKGKIQDLSLDDYKGKYVVLFWYPMDFTFVCPTEIIAFNDAMDEFKSLDCQLIAASCDSEYVHQAWINTPRHQGGLGPETHIPIISDTTHTIAKQYGVYLESGITLRGLFIIDTQGIIRQITINDLPVGRNVAEIIRLVEAFQFTDKHGQVCPADWNRGSKTISLDREKAKAYFADDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MYS1</accession>
    <name>A0A1C7MYS1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">A0J61_09961</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000984">
        <property type="protein sequence ID" value="OBZ81990.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MYS1"/>
    <dbReference type="STRING" id="101091.A0A1C7MYS1"/>
    <dbReference type="InParanoid" id="A0A1C7MYS1"/>
    <dbReference type="OrthoDB" id="1368at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005254">
        <property type="term" value="F:chloride channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044669">
        <property type="entry name" value="YneE/VCCN1/2-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33281">
        <property type="entry name" value="UPF0187 PROTEIN YNEE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33281:SF19">
        <property type="entry name" value="VOLTAGE-DEPENDENT ANION CHANNEL-FORMING PROTEIN YNEE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25539">
        <property type="entry name" value="Bestrophin_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6" id="KW-0406">Ion transport</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="40"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="69"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="332"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="357"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="197"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="224"/>
            <end position="247"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OBZ81990.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="423" mass="47720" checksum="6C8368C554830ECF" modified="2016-11-30" version="1">MSIEDRVDHLVHDSTPAYYTRRWVKRISTYPDHLRVKGSVLPAILPLVILTGVYAYFIGVMYITWGWNIALSNSIVPVLSVVLGLLLAFRANTSYARYYEGRQLWQDLSSNTRNLARLVWCSIPERTQNDHLEKMRCMKLLLAFAVATKHYLRRELGIDYYDLDYLLPPNWIPAAADDRLFIIQDESSDEEGVVVTSVKRDGSQGQGMLNVNEGGGDHIDDLDNQQLASGPASSAVSTVDNSGTSTIQDEDRPRHQKKKKKRFVSDEDLPDEGNSDMSLPLEIIFRLSLYMEQAKSSGKIDGQFSNVIITHLNNLNDCLSGMERIVNTPIPAVYVVHLKQSVVLYILATPFTLIDQLGWWIVPTLVLAAFILFGIDAIGAQIDNPFGYNSNDFPLNTFCDALRKEIEFIVYHLPCETENAMLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MZ78</accession>
    <name>A0A1C7MZ78_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_10233</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001081">
        <property type="protein sequence ID" value="OBZ81716.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MZ78"/>
    <dbReference type="InParanoid" id="A0A1C7MZ78"/>
    <dbReference type="OrthoDB" id="2268209at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="119"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="119"/>
            <end position="128"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ81716.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="258" mass="28374" checksum="BB76E751D4D41ED0" modified="2016-11-30" version="1">MREVSRVKKQLSNAKKDVINNYFWDNHAIALQQDIVDRQRSQSKLETSIISIKSLLMSQHSKQLEQSLISTKRLQESSPASTSFKKQLVNSSSSTSYLKVLTLSDEELSIRLSSDFLPSTSNLSTETENSPKHATDTSPPTPSGRLSSAPKLNDTPPSLSLPTKSGLLDSPLPILEANAKSSHPVSEVVETDGVVCDTTKLSIATIIKREAINLHDQYKHGNPLSSRQRKIMSNGLPSILDLVDQSYTSQQKLFASAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MZY4</accession>
    <name>A0A1C7MZY4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 10">Protein-S-isoprenylcysteine O-methyltransferase</fullName>
            <ecNumber evidence="3 10">2.1.1.100</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">icmt</name>
        <name evidence="11" type="ORF">A0J61_09619</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>[protein]-C-terminal S-[(2E,6E)-farnesyl]-L-cysteine + S-adenosyl-L-methionine = [protein]-C-terminal S-[(2E,6E)-farnesyl]-L-cysteine methyl ester + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:21672"/>
            <dbReference type="Rhea" id="RHEA-COMP:12125"/>
            <dbReference type="Rhea" id="RHEA-COMP:12126"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:90510"/>
            <dbReference type="ChEBI" id="CHEBI:90511"/>
            <dbReference type="EC" id="2.1.1.100"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Endoplasmic reticulum membrane</location>
            <topology evidence="10">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the class VI-like SAM-binding methyltransferase superfamily. Isoprenylcysteine carboxyl methyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.100" evidence="3 10"/>
    <dbReference type="EMBL" id="LUGH01000892">
        <property type="protein sequence ID" value="OBZ82331.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MZY4"/>
    <dbReference type="FunCoup" id="A0A1C7MZY4">
        <property type="interactions" value="315"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7MZY4"/>
    <dbReference type="InParanoid" id="A0A1C7MZY4"/>
    <dbReference type="OrthoDB" id="422086at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005637">
        <property type="term" value="C:nuclear inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004671">
        <property type="term" value="F:protein C-terminal S-isoprenylcysteine carboxyl O-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007323">
        <property type="term" value="P:peptide pheromone maturation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031139">
        <property type="term" value="P:positive regulation of conjugation with cellular fusion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1630">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007269">
        <property type="entry name" value="ICMT_MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025770">
        <property type="entry name" value="PPMT_MeTrfase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12714">
        <property type="entry name" value="PROTEIN-S ISOPRENYLCYSTEINE O-METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12714:SF9">
        <property type="entry name" value="PROTEIN-S-ISOPRENYLCYSTEINE O-METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04140">
        <property type="entry name" value="ICMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51564">
        <property type="entry name" value="SAM_ICMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 10 11" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 10" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="5 11" id="KW-0808">Transferase</keyword>
    <keyword evidence="7 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="44"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="72"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="113"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="141"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="195"/>
            <end position="219"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU362022"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="OBZ82331.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="257" mass="30060" checksum="3C5A6270F108ECA3" modified="2016-11-30" version="1">MRSPGLNIRHTTLEGTTSPIQHIDRSNIKDEIRLFDGENTPQNIAVYGFLLGMLCCAGFMFAILASTAIPQFGLFLSALALFHFLEYLATALFNADKLTLDSYLINHSTHYHAAHAAALIEFLVEYYFFPRYKQFGWLNYLGLLLVLMGQLCRTIAMFSARHNFSHHIADYKAHDHVLVKHGIYSVMRHPSYFGFYWWALGVQILLMNPICFGLFVYWLQRFFSERIQYEEHTLDRFFGQEWKEYKQKTPTLMPYIQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-06-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N046</accession>
    <name>A0A1C7N046_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_11217</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001789">
        <property type="protein sequence ID" value="OBZ80734.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="InParanoid" id="A0A1C7N046"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ80734.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="197" mass="22324" checksum="9824F9640D96C83C" modified="2016-11-30" version="1">MVERSNEILKKLVVVEDKEQSQFAGNQLEVIVLPACLISGPHIKDVHGDSNTPLNRFKYFLTSCSGDSINSTDRAKKEAMMKLNXSTLEQLSKAGLVDLLYQEEDLISYYFRYKKSDQLPKFKRDQGSESSKDKPPVEGVRAAVTRENVPHHLFKVTLGDNELDPDLTTIISDSAFVQQGDKRLLNNTDYQRSNKMM</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N059</accession>
    <name>A0A1C7N059_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_09416</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000845">
        <property type="protein sequence ID" value="OBZ82535.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N059"/>
    <dbReference type="InParanoid" id="A0A1C7N059"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="23"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ82535.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="56" mass="6350" checksum="6A95F19A3A23A9DA" modified="2016-11-30" version="1" fragment="single">MFSQQQQQQQQQQQDFGMDNSDHNSMFINTPRSGNNFDQPQASSPYGMSSTSFGPM</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N0N8</accession>
    <name>A0A1C7N0N8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_09763</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000930">
        <property type="protein sequence ID" value="OBZ82189.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N0N8"/>
    <dbReference type="InParanoid" id="A0A1C7N0N8"/>
    <dbReference type="OrthoDB" id="2206100at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ82189.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="67" mass="7339" checksum="BA13F5E65AAF3615" modified="2016-11-30" version="1">MTTSKFVNYFLFPVTTVALIGTIVRSQAKPSKAYTQFMKPDGQARNQWQKLNDGLGVNDVGRSCGGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N0T7</accession>
    <name>A0A1C7N0T7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">3'(2'),5'-bisphosphate nucleotidase</fullName>
            <ecNumber evidence="3">3.1.3.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">tol1</name>
        <name evidence="11" type="ORF">A0J61_09714</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>3'-phosphoadenylyl sulfate + H2O = adenosine 5'-phosphosulfate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:77639"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58243"/>
            <dbReference type="ChEBI" id="CHEBI:58339"/>
            <dbReference type="EC" id="3.1.3.7"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="9">
            <dbReference type="Rhea" id="RHEA:77640"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>adenosine 2',5'-bisphosphate + H2O = AMP + phosphate</text>
            <dbReference type="Rhea" id="RHEA:77643"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:194156"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="3.1.3.7"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="7">
            <dbReference type="Rhea" id="RHEA:77644"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>adenosine 3',5'-bisphosphate + H2O = AMP + phosphate</text>
            <dbReference type="Rhea" id="RHEA:10040"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58343"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="3.1.3.7"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="8">
            <dbReference type="Rhea" id="RHEA:10041"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 10">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the inositol monophosphatase superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.7" evidence="3"/>
    <dbReference type="EMBL" id="LUGH01000917">
        <property type="protein sequence ID" value="OBZ82239.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N0T7"/>
    <dbReference type="FunCoup" id="A0A1C7N0T7">
        <property type="interactions" value="78"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N0T7"/>
    <dbReference type="InParanoid" id="A0A1C7N0T7"/>
    <dbReference type="OrthoDB" id="411145at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008441">
        <property type="term" value="F:3'(2'),5'-bisphosphate nucleotidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052829">
        <property type="term" value="F:inositol-1,3,4-trisphosphate 1-phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004441">
        <property type="term" value="F:inositol-1,4-bisphosphate 1-phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042538">
        <property type="term" value="P:hyperosmotic salinity response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009086">
        <property type="term" value="P:methionine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046854">
        <property type="term" value="P:phosphatidylinositol phosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000103">
        <property type="term" value="P:sulfate assimilation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016078">
        <property type="term" value="P:tRNA decay"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd01517">
        <property type="entry name" value="PAP_phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.190.80:FF:000003">
        <property type="entry name" value="PAP-specific phosphatase HAL2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.190.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.540.10">
        <property type="entry name" value="Fructose-1,6-Bisphosphatase, subunit A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006239">
        <property type="entry name" value="DPNP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020583">
        <property type="entry name" value="Inositol_monoP_metal-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051090">
        <property type="entry name" value="Inositol_monoP_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000760">
        <property type="entry name" value="Inositol_monophosphatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020550">
        <property type="entry name" value="Inositol_monophosphatase_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01330">
        <property type="entry name" value="bisphos_HAL2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43200:SF6">
        <property type="entry name" value="3'(2'),5'-BISPHOSPHATE NUCLEOTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43200">
        <property type="entry name" value="PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00459">
        <property type="entry name" value="Inositol_P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00377">
        <property type="entry name" value="IMPHPHTASES"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56655">
        <property type="entry name" value="Carbohydrate phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00629">
        <property type="entry name" value="IMP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00630">
        <property type="entry name" value="IMP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6 10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="4 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="10">
        <location>
            <position position="70"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="128"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="130"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="131"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="275"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012633"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00044466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00044479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00044484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR600760-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="OBZ82239.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="333" mass="36239" checksum="6CB3CEE8AF2C5E87" modified="2016-11-30" version="1">MNDYAQERKVAIQAVLTASKVCQSVFQHLVANETLTKNDKSPVTVADFSAQAIVNTCLEKHFPNDPIVGEEDSRDLQGDVGKVLREKVYSLTNGVLDQNEKLTEQQILNAIDRGNYIGGSKGRHWALDPIDGTKGFLRGGQYAVCLALIVDGIVQLGVVGCPNLPVDHQKPEGERGSLFIAIRGQGAFQRSFTDATETPIHFADITSTEEATFCESVEAGHSSHGDAEEIAKLLGITREPVRMDSQAKYCSISRGDADIYLRLPTSKTYIEKIWDHASGNVLVTEAGGKVTDVHGQPLDFSIGRTLEKNKGVIASKASIHDRVLEAVQKVLKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N1B4</accession>
    <name>A0A1C7N1B4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Type-1 angiotensin II receptor-associated protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">Agtrap</name>
        <name evidence="3" type="ORF">A0J61_09069</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000767">
        <property type="protein sequence ID" value="OBZ82880.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N1B4"/>
    <dbReference type="InParanoid" id="A0A1C7N1B4"/>
    <dbReference type="OrthoDB" id="2500246at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009436">
        <property type="entry name" value="AGTRAP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06396">
        <property type="entry name" value="AGTRAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0675">Receptor</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008889416" evidence="2">
        <location>
            <begin position="32"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="59"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="88"/>
            <end position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ82880.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="148" mass="16210" checksum="B706742CFC71B80B" modified="2016-11-30" version="1">MDFVQSTVQQTNLASLLGLHLGLSLLGAVASNPTYNIPIFFFGIWAYNNRDSTTPLKTFTGSLGFSIFLDLIWFYLHGNNALNESGFGFAKFFNIVSLFAKPFTVYSSINILKERGDSLNVGSWSDAPGAFPSSGYQNVRDGDSAEFP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N2C4</accession>
    <name>A0A1C7N2C4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Trehalose phosphorylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">TP</name>
        <name evidence="9" type="ORF">A0J61_08685</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="2">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the glycosyltransferase group 1 family. Glycosyltransferase 4 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000693">
        <property type="protein sequence ID" value="OBZ83263.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N2C4"/>
    <dbReference type="STRING" id="101091.A0A1C7N2C4"/>
    <dbReference type="InParanoid" id="A0A1C7N2C4"/>
    <dbReference type="OrthoDB" id="937291at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006006">
        <property type="term" value="P:glucose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2000">
        <property type="entry name" value="Glycogen Phosphorylase B"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001296">
        <property type="entry name" value="Glyco_trans_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052078">
        <property type="entry name" value="Trehalose_Metab_GTase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049438">
        <property type="entry name" value="TreT_GT1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47779">
        <property type="entry name" value="SYNTHASE (CCG-9), PUTATIVE (AFU_ORTHOLOGUE AFUA_3G12100)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47779:SF1">
        <property type="entry name" value="SYNTHASE (CCG-9), PUTATIVE (AFU_ORTHOLOGUE AFUA_3G12100)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00534">
        <property type="entry name" value="Glycos_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21269">
        <property type="entry name" value="TreT_GT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53756">
        <property type="entry name" value="UDP-Glycosyltransferase/glycogen phosphorylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="3" id="KW-0313">Glucose metabolism</keyword>
    <keyword evidence="4" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Trehalose synthase N-terminal" evidence="8">
        <location>
            <begin position="224"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyl transferase family 1" evidence="7">
        <location>
            <begin position="440"/>
            <end position="614"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022526"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF21269"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OBZ83263.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="682" mass="78376" checksum="A17C35DE0F147A81" modified="2016-11-30" version="1">MPPSPTRVPIRRTSRRFSSAHVPMPVYLGVDFEIRDDNTSWYAISVHDGMYSTDYYQGELKKHDPSKSPKEIIIEAFVKLHEIVQLYSMAQNYKVQLVACSYDIGNRLLKTNEELIDFEEIYTMSDYWQELDALPFRVETHAVSADERASAAVRKAVMWLSPKYPGNLPRISVGYRHEVEVDFNHSITMVNCLDYQKTVRKQTWDLFQNMVSQFKERNLKVSFFNSTPQGGGVALMRHALIRLLHLNGVDVHWYVARPKPEVFDITKRKFHNVLQGVADSSVWLTDEDKQAFIDWSDENVRRFWLDDNGPIKTSDVIVIDDPQVSGIIPYIRQYAPNTRIIFRSHIEVRSDLIQNQPEGSTANTWNFLWDFIKLADIFVAHPIKGFVPDVVPPENTVLLPAATDPLDGLNKPMNDWCITYYQSVFNRVCVDCGVNEVDWNRPYIVQVARFDPSKGIPDVLEAYRLLRLKMDGEFEDHRTPQLVICGHGSIDDPDGTLIFEQVQNTIESTKFAFIASDIIAVRLPPSDQLLNMIMRCSYVALQLSHREGFEVKVTEALHKGIPVVAYKAGGIPLQIEHEKSGFLLPIGDVEQVADVLYRLFKEPELHRKMSANAKACVTEEFFTIWNAMSWLHMFLELTGHQSDEMHQNGGLLNLSTLKHTTLGDQRKVSETWREKYNYDDSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N2P8</accession>
    <name>A0A1C7N2P8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Homeobox protein HD-10</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">HD-10_4</name>
        <name evidence="9" type="ORF">A0J61_08592</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 5 6">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000677">
        <property type="protein sequence ID" value="OBZ83360.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N2P8"/>
    <dbReference type="STRING" id="101091.A0A1C7N2P8"/>
    <dbReference type="InParanoid" id="A0A1C7N2P8"/>
    <dbReference type="OrthoDB" id="6159439at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030154">
        <property type="term" value="P:cell differentiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00086">
        <property type="entry name" value="homeodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001356">
        <property type="entry name" value="HD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051000">
        <property type="entry name" value="Homeobox_DNA-bind_prot"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24324:SF5">
        <property type="entry name" value="HEMATOPOIETICALLY-EXPRESSED HOMEOBOX PROTEIN HHEX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24324">
        <property type="entry name" value="HOMEOBOX PROTEIN HHEX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00046">
        <property type="entry name" value="Homeodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00389">
        <property type="entry name" value="HOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50071">
        <property type="entry name" value="HOMEOBOX_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 5 6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3 5 6" id="KW-0371">Homeobox</keyword>
    <keyword evidence="4 5 6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Homeobox" evidence="8">
        <location>
            <begin position="54"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="Homeobox" evidence="5">
        <location>
            <begin position="56"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="27"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OBZ83360.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="119" mass="13753" checksum="273348BF1139E531" modified="2016-11-30" version="1">MSSYTLPSLSDVLSPSVMLELSQRKSLDFGQTQSRKPLSVHDLITPSPKVHQREGAKNKRKRVSPSQLAVLNFTFEQTRFPSLELRMKLGKQLDMTPRAVQIWFQNKRQSIRTREKTIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N2R2</accession>
    <name>A0A1C7N2R2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="10">High-affinity glucose transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">HGT1_5</name>
        <name evidence="10" type="ORF">A0J61_08512</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000663">
        <property type="protein sequence ID" value="OBZ83435.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N2R2"/>
    <dbReference type="FunCoup" id="A0A1C7N2R2">
        <property type="interactions" value="330"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N2R2"/>
    <dbReference type="InParanoid" id="A0A1C7N2R2"/>
    <dbReference type="OrthoDB" id="4142200at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005351">
        <property type="term" value="F:carbohydrate:proton symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd17356">
        <property type="entry name" value="MFS_HXT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000026">
        <property type="entry name" value="MFS quinate transporter QutD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050360">
        <property type="entry name" value="MFS_Sugar_Transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00879">
        <property type="entry name" value="SP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022:SF7">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00171">
        <property type="entry name" value="SUGRTRNSPORT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00216">
        <property type="entry name" value="SUGAR_TRANSPORT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00217">
        <property type="entry name" value="SUGAR_TRANSPORT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0762">Sugar transport</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="51"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="82"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="112"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="141"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="173"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="258"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="304"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="330"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="373"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="408"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="437"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="9">
        <location>
            <begin position="14"/>
            <end position="462"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OBZ83435.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="513" mass="56807" checksum="7680900B538F6A81" modified="2016-11-30" version="1">MGYLTKLTTNIYSIGAFAAIAGIMFGFDIGSNSGVIGFPQYQEYFNRPSEVLQGGINGALSAGCFVGALFAGYPADKYSRKFTLIGASVLFVIGSILQAAANGVAMLCVGRVINGLSVGITSMVVPLYQSEVAPKEIRGRIVAVQQWSITWGILISFWIQYGCHYIQSTAAFRIPWGIQGVPALILCLGFWAFPHSPRWLADQGRMDDALKVLADIHGNGDPNHPRVMTEIEEIRASIHFDKEVASHRYSDLFKPGMFYRVSLGVCLQIWQQLTGMNIIMFYVVFLFQQAGIGSSDEATLVSSGVSYVINVVMTIPAILFVDKWGRRPTLIFGALLMSTFLWAVGGVLATGDWSIGPNGKSLVTLHSKSQADGVVACIYLFVATFATTWGPLGWIYPSEIYPLRVRAMAVSLSTASNWLFNWVLNFVVPLLMERIHYGLYLLFAGFNFLMAVHVYLAYPETKGFTLEEMDIIFEHNPRKKISKETLDAWNEQRGLRRTEEIGSIEKKAREDSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N2Y6</accession>
    <name>A0A1C7N2Y6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Polymerase/histidinol phosphatase N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">A0J61_08539</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000667">
        <property type="protein sequence ID" value="OBZ83411.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N2Y6"/>
    <dbReference type="InParanoid" id="A0A1C7N2Y6"/>
    <dbReference type="OrthoDB" id="16564at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035312">
        <property type="term" value="F:5'-3' DNA exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004534">
        <property type="term" value="F:5'-3' RNA exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.140">
        <property type="entry name" value="Metal-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004013">
        <property type="entry name" value="PHP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052018">
        <property type="entry name" value="PHP_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003141">
        <property type="entry name" value="Pol/His_phosphatase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016195">
        <property type="entry name" value="Pol/histidinol_Pase-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF038032">
        <property type="entry name" value="CehA_McbA_metalo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42924">
        <property type="entry name" value="EXONUCLEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42924:SF3">
        <property type="entry name" value="POLYMERASE_HISTIDINOL PHOSPHATASE N-TERMINAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02811">
        <property type="entry name" value="PHP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00481">
        <property type="entry name" value="POLIIIAc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89550">
        <property type="entry name" value="PHP domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="51"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="379"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="domain" description="Polymerase/histidinol phosphatase N-terminal" evidence="3">
        <location>
            <begin position="112"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OBZ83411.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="423" mass="48278" checksum="2E3C69C029785F3D" modified="2016-11-30" version="1">MHKRGNSPSLQNSFQELPQEPPSISSAKQLHSTHSQPHLTRYVSTDYLWGLLYRVISLIVIIGVLIAIGIGLRYTDNMPKPEDFSQLTFDWKINPRDYLQPYNSSFQYNVLLDGHTHSTYSDGKMNVRQLLEWHIANGYNAVMVTDHNTIRGGLAAEKLALEEYNQSIVVIPGMEYTCCRIHMNFLDINETVPVTGPVPTDEELQQAIARVHALGGLVIVNHIPWSNTTESGYQLPRLPNHPSIEQLISWGVDGFEVINQETFDLTSYQTTLRNNLIAMVGMDLHHPSVGAQVWLTVNAPELTRAGIMQEIRARRTSFLFDPAGTRPRAYVDSPASYRALTPLTYLGDYFGMFYDDLKGMYSFQGTFCHPEQMSVHGSVIGWFIFWVFVFMIAFELVRWICVLSWNQGFPNRKRCRRRNSDVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N3J6</accession>
    <name>A0A1C7N3J6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">leucine--tRNA ligase</fullName>
            <ecNumber evidence="3">6.1.1.4</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Leucyl-tRNA synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="primary">lrs1</name>
        <name evidence="14" type="ORF">A0J61_08300</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>tRNA(Leu) + L-leucine + ATP = L-leucyl-tRNA(Leu) + AMP + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:11688"/>
            <dbReference type="Rhea" id="RHEA-COMP:9613"/>
            <dbReference type="Rhea" id="RHEA-COMP:9622"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57427"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78494"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.4"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the class-I aminoacyl-tRNA synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.4" evidence="3"/>
    <dbReference type="EMBL" id="LUGH01000626">
        <property type="protein sequence ID" value="OBZ83650.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N3J6"/>
    <dbReference type="FunCoup" id="A0A1C7N3J6">
        <property type="interactions" value="840"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N3J6"/>
    <dbReference type="InParanoid" id="A0A1C7N3J6"/>
    <dbReference type="OrthoDB" id="10249672at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002161">
        <property type="term" value="F:aminoacyl-tRNA deacylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004823">
        <property type="term" value="F:leucine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990825">
        <property type="term" value="F:sequence-specific mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006429">
        <property type="term" value="P:leucyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:1903432">
        <property type="term" value="P:regulation of TORC1 signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd07959">
        <property type="entry name" value="Anticodon_Ia_Leu_AEc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.740.10:FF:000001">
        <property type="entry name" value="Leucine--tRNA ligase, cytoplasmic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.730.10">
        <property type="entry name" value="Isoleucyl-tRNA Synthetase, Domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.740.10">
        <property type="entry name" value="Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002300">
        <property type="entry name" value="aa-tRNA-synth_Ia"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004493">
        <property type="entry name" value="Leu-tRNA-synth_Ia_arc/euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013155">
        <property type="entry name" value="M/V/L/I-tRNA-synth_anticd-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055416">
        <property type="entry name" value="RBD_LARS1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009080">
        <property type="entry name" value="tRNAsynth_Ia_anticodon-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009008">
        <property type="entry name" value="Val/Leu/Ile-tRNA-synth_edit"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00395">
        <property type="entry name" value="leuS_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF008957">
        <property type="entry name" value="PRK12300.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45794:SF1">
        <property type="entry name" value="LEUCINE--TRNA LIGASE, CYTOPLASMIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45794">
        <property type="entry name" value="LEUCYL-TRNA SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08264">
        <property type="entry name" value="Anticodon_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24810">
        <property type="entry name" value="RBD_LARS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00133">
        <property type="entry name" value="tRNA-synt_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47323">
        <property type="entry name" value="Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52374">
        <property type="entry name" value="Nucleotidylyl transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50677">
        <property type="entry name" value="ValRS/IleRS/LeuRS editing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 14" id="KW-0436">Ligase</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aminoacyl-tRNA synthetase class Ia" evidence="11">
        <location>
            <begin position="50"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="domain" description="Aminoacyl-tRNA synthetase class Ia" evidence="11">
        <location>
            <begin position="191"/>
            <end position="762"/>
        </location>
    </feature>
    <feature type="domain" description="Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding" evidence="12">
        <location>
            <begin position="800"/>
            <end position="949"/>
        </location>
    </feature>
    <feature type="domain" description="Leucine--tRNA ligase RagD-binding" evidence="13">
        <location>
            <begin position="971"/>
            <end position="1037"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005594"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00030520"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00047469"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF08264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF24810"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="OBZ83650.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="1093" mass="124002" checksum="42948FE90BC49EAE" modified="2016-11-30" version="1">MVAMAAEAPKTAKRDALRALEGKARSLWDAEKTFEINAPTIEEHPNSEDLQQAYPKYMSTMPYPYMNGRLHLGHAFTFSKIEFGTGYERMKGKRALLPQGFHCTGMPIKASADKIVREMEMFGKYFEKFDEVALAKELEEKAEVKNVKSKVAAKTGNVTYQFQIMLSLGIPKEEIHKFADPYYWTEFFPPQTMSDLNAFGAKVDWRRSFITTDANPYYDSFVRWQMRKLKAMQKIKFGERYTIYSILDNQPCMDHDRASGEAVGPQEYTGIKMKVLEWSAPAQEALAAHADALKGKNVFLVAATLRPETMYGQTNCFVGPDLEYGIYNINDTDAYLCTERAARNMSQQKIFANGRTTIEKLADIKGAAVVGSKIHAPLSTYPFVYVLPMETVLSTKGTGVVTSVPSDSPDDFATLTDLKKKPEYYKIDPSWVEGFEPIPIIDTPNYGNLIAPKLCEIKKINSQKDRLQLAEAKEIAYKEGFYQGTMCIGDFKGEKVQDAKPKLREALIKSGEAFAYSEPESLIISRSGDECVVALLDQWYIDYGEEEWLAKAKKCLAQMNTYTNETRNQFDSVLDWLNKWACARSFGLGTKLPWDEQFLVESLSDSTIYMAYYTVANLLHGGSINGRTVGPAGIKPEQLTDGVWDYIFKVGDYPADSTVSQATLDRLRREYEYFYPLDIRVSGKDLIPNHLTFFIYNHTAIFPESMWPRGIRSNGHLMLDSKKMSKSTGNFMTMNDAVLKYGADATRLALADAGDSVEDANFEDSTANAAILRLHTLLEWIEDQISKQDQLRQGELNFFDKIFENEMNKLILETQNAYEETYYREVLKHGLFEFQAAKDAYQQASVECGMHKDLVMRYIEYQAFVECGMHKDLVMRYIEYQALLIAPITPHWSEHIWQSILKREGLVVSARFPTPSAPVDEALDDATRYIRKTTKSVRDAEIALGKKKKKGKVAENEYKPNEPKTLKIYAATKFPEWQEACLATMKDNYKDGQFDDSKIRAELGAQGILKNKKAMPFVQEQKKLVLKDGPSAFNRALTFNEVDILEKAKDELKRALGFHTITILGHEQWTEEDLKAAESSVPGAPSFSFKNEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N3L7</accession>
    <name>A0A1C7N3L7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Peptidyl-prolyl isomerase CWC27</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Peptidyl-prolyl isomerase cwc27</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8 9">Rotamase CWC27</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="primary">cwc27</name>
        <name evidence="13" type="ORF">A0J61_08246</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. Involved in pre-mRNA splicing.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 15">
            <text>[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)</text>
            <dbReference type="Rhea" id="RHEA:16237"/>
            <dbReference type="Rhea" id="RHEA-COMP:10747"/>
            <dbReference type="Rhea" id="RHEA-COMP:10748"/>
            <dbReference type="ChEBI" id="CHEBI:83833"/>
            <dbReference type="ChEBI" id="CHEBI:83834"/>
            <dbReference type="EC" id="5.2.1.8"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the cyclophilin-type PPIase family. CWC27 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000618">
        <property type="protein sequence ID" value="OBZ83703.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N3L7"/>
    <dbReference type="FunCoup" id="A0A1C7N3L7">
        <property type="interactions" value="382"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N3L7"/>
    <dbReference type="InParanoid" id="A0A1C7N3L7"/>
    <dbReference type="OrthoDB" id="442970at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071013">
        <property type="term" value="C:catalytic step 2 spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01925">
        <property type="entry name" value="cyclophilin_CeCYP16-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.100.10:FF:000007">
        <property type="entry name" value="Peptidyl-prolyl cis-trans isomerase CWC27 homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.100.10">
        <property type="entry name" value="Cyclophilin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029000">
        <property type="entry name" value="Cyclophilin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020892">
        <property type="entry name" value="Cyclophilin-type_PPIase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002130">
        <property type="entry name" value="Cyclophilin-type_PPIase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044666">
        <property type="entry name" value="Cyclophilin_A-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45625">
        <property type="entry name" value="PEPTIDYL-PROLYL CIS-TRANS ISOMERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45625:SF6">
        <property type="entry name" value="SPLICEOSOME-ASSOCIATED PROTEIN CWC27 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00160">
        <property type="entry name" value="Pro_isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00153">
        <property type="entry name" value="CSAPPISMRASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50891">
        <property type="entry name" value="Cyclophilin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00170">
        <property type="entry name" value="CSA_PPIASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50072">
        <property type="entry name" value="CSA_PPIASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="13" id="KW-0413">Isomerase</keyword>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PPIase cyclophilin-type" evidence="12">
        <location>
            <begin position="18"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="244"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="451"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="10">
        <location>
            <begin position="177"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="251"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="314"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="459"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="483"/>
            <end position="494"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00038509"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00055615"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00067721"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00071024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00082698"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00083804"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="OBZ83703.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="494" mass="56792" checksum="37B1076E1E196BBA" modified="2016-11-30" version="1">MSNIYALEPHTNAKVILHTTSGDIEIELWGKEAPRATRNFIQLCLEGYYDNTIFHRIVPDFLVQGGDPTGTGQGGESIYEDGFPDEFHSRLRFNRRGLVGLANTGQDDNGSQFFITLDRADELTRKHTLFGRVAGDTLFNVMKMTELELDANERPLYPPRIRSAEVVLNPFDDIIPRITAEEKKQAKLLEQKKLEEQAQKKKKKGQKKQLNLLSFGEEAAELEPPAAEKTKMKSSYDFMEHTAAADPSILEDIKSEQVSKPSEKQTEKPTEKQTEKQTEKQTEKPVKAEKPVEKPVERKKKETPPPPPPSTQDTIEKLKQDIRNISKPSPTSDLPVPEKKEKKKSLVALEREKYVSQQKKKPSKKNKVDDSDVLDQLLAFRKKLSTSQPATEAESKKEQKICELHDIPNCESCFDASQFNGEDETDDGWISHRLVFDKDLKGKDLMQRKETVDDYVVIDPRDRSAKAKQEEYERKRSSRKRHREDERDERKRRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N3P3</accession>
    <name>A0A1C7N3P3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="1">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">nrc-2_2</name>
        <name evidence="11" type="ORF">A0J61_08213</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="1"/>
    <dbReference type="EMBL" id="LUGH01000612">
        <property type="protein sequence ID" value="OBZ83732.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N3P3"/>
    <dbReference type="FunCoup" id="A0A1C7N3P3">
        <property type="interactions" value="198"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N3P3"/>
    <dbReference type="InParanoid" id="A0A1C7N3P3"/>
    <dbReference type="OrthoDB" id="432483at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05574">
        <property type="entry name" value="STKc_phototropin_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:001236">
        <property type="entry name" value="AGC/RSK protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000121">
        <property type="entry name" value="Serine/threonine-protein kinase nrc-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45637">
        <property type="entry name" value="FLIPPASE KINASE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 11" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="10">
        <location>
            <begin position="137"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="284"/>
            <end position="303"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="OBZ83732.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="505" mass="56917" checksum="74C7F2D03E4D2B96" modified="2016-11-30" version="1">METKDVAMEISAPPPSYMQSPMTMRMKSFLPASPTLPTFSVPNDFDTHSQKGFKSNSWFSQSGNNTDKQTAIRRVASVPNTKFFELSNQSYNSNSTVSIPSLMTDSPPMQKLRRLCRRTYSSSSIKVKKVEVGPSSFVKIRMLGKGDVGKVYMVRQKETDKLYAMKVLSKREMIRRNKIKRALAEQEILTTSNHPFIVTLYHSFQSQDYLYFVMEYCVGGEFFRALQLRPGKCLSEEGAKFYAAEVTAALEYLHLQGHIYRDLKPENILLHQSGHIMLSDFDLSKGSQPPGNPSVVKSGSPHVPPSIDTKSCVINLRTNSFVGTEEYIAPEVIKGCGHTSAVDWWTLGILIYEMLFGTTPFKGSGRNETFSRVLHCDVQFGEQPAPYKTTISSNGKNLIRKLLHKDEHKRLGSKAGASDVKSHPFFKNINFALLRHSTPPITPLVQKPNGIDALNFRKMTPESMSLDLESDHVLVSLKEDENPFEKFNSITLYHEGDSDSDDYDY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N4X8</accession>
    <name>A0A1C7N4X8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DEK-C domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_07878</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000559">
        <property type="protein sequence ID" value="OBZ84077.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N4X8"/>
    <dbReference type="STRING" id="101091.A0A1C7N4X8"/>
    <dbReference type="InParanoid" id="A0A1C7N4X8"/>
    <dbReference type="OrthoDB" id="552755at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014876">
        <property type="entry name" value="DEK_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037647">
        <property type="entry name" value="HIRIP3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15410">
        <property type="entry name" value="HIRA-INTERACTING PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15410:SF2">
        <property type="entry name" value="HIRA-INTERACTING PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08766">
        <property type="entry name" value="DEK_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51998">
        <property type="entry name" value="DEK_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DEK-C" evidence="2">
        <location>
            <begin position="9"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="73"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="254"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="73"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="102"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="115"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="140"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="282"/>
            <end position="327"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51998"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ84077.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="327" mass="37184" checksum="D9F7CD8B5F11DCAA" modified="2016-11-30" version="1">MTNQLSEKFLNSREFQAKLKNIIDEGDMNVLTAFDIRQMLETYFGFEKDALSAKPYKKIVNSLIDKFISSGSDILQNNSQPAESTKRKASVELEDEDDILPSKRKSMKKKAKIESDDEERKEEKSEEEGESEEENEDYSPVEVEPKKNASTKTKSTTSQPKKKASTKAELTIAPGSEKDEDTIKRLKQFISKCGVRKVWSKELADCKNTREEIAKLKNMLKDLGVHGRPSIEKCEAIKRERELKAELDSLDTSLIIDQANERPTRRSRNAVGKPNYTIDTVTDSEEEELDDDNNEAEEVEEGSGDENEDEETASESEDEFRDSSDEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N4Z6</accession>
    <name>A0A1C7N4Z6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Rho GTPase-activating protein 15</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">ARHGAP15_0</name>
        <name evidence="4" type="ORF">A0J61_07772</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000545">
        <property type="protein sequence ID" value="OBZ84182.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N4Z6"/>
    <dbReference type="STRING" id="101091.A0A1C7N4Z6"/>
    <dbReference type="InParanoid" id="A0A1C7N4Z6"/>
    <dbReference type="OrthoDB" id="79452at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.60">
        <property type="entry name" value="Arfaptin homology (AH) domain/BAR domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.555.10">
        <property type="entry name" value="Rho GTPase activation protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027267">
        <property type="entry name" value="AH/BAR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050729">
        <property type="entry name" value="Rho-GAP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008936">
        <property type="entry name" value="Rho_GTPase_activation_prot"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000198">
        <property type="entry name" value="RhoGAP_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23176:SF134">
        <property type="entry name" value="RHO-TYPE GTPASE-ACTIVATING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23176">
        <property type="entry name" value="RHO/RAC/CDC GTPASE-ACTIVATING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00620">
        <property type="entry name" value="RhoGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00324">
        <property type="entry name" value="RhoGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103657">
        <property type="entry name" value="BAR/IMD domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48350">
        <property type="entry name" value="GTPase activation domain, GAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50238">
        <property type="entry name" value="RHOGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0343">GTPase activation</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rho-GAP" evidence="3">
        <location>
            <begin position="396"/>
            <end position="583"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="192"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="212"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="228"/>
            <end position="237"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022468"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50238"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OBZ84182.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="635" mass="72093" checksum="3EE30B4D01B169F4" modified="2016-11-30" version="1">MHRSTKSLSGGQDEEIISINAQQDYVNKVLKWSILDLERFIQTLKTRITVEEAYVSALVKTTKSTHTNNGTIENTGSSTNTIDIHNYFGDYATTSLQTSSQYEKTVERTIEVRREFIANVKSQVELLIKVKDSHEQRRKKVKAVLGEKNTNYIDFRTREIVKLSKAYNNKCSEYASLQQQILISSHEDNASINSSSPLMHEGHLSPQMIRSSSEEPRVSNDSIRDDNSMTSHESSMVHNKKNGMAGFITQMRSQLASAAAGDPSKQAARVARLKKEISDAAGIDQEYRQGIRVLEFLRKKQIETAIHAMRHVEAILLAKSDIVKAAMVTICKQHEDTLSNELNILNQMFDVVAKVDGKKDIERFLAEYQKLSFTKPKPIFYDNYYYGRCKEILFGSNLNEYAVEHNRTIPLLVTKCIHSVEKLGGLEKEGIYRVSGRQSNVDQLKSEFERDEESVELLESKFDVFTIAAVLKIYLRELKQPLFHLTMQERIDYSKIKEETKRTMILQNKLAELSQPQRDTLHVLVAHLAKVQDKSHINKMTLKNLSVIFTPALFHDHNQAESTGEWYADKVLEDLILKHDVLFVGAQSQVEKQEVPASAAQQAEQQLIDDSAALNVNLSAIGKRLSAVKVPLFDT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N646</accession>
    <name>A0A1C7N646_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Monocarboxylate transporter 12</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">Slc16a12</name>
        <name evidence="5" type="ORF">A0J61_07870</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000558">
        <property type="protein sequence ID" value="OBZ84079.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N646"/>
    <dbReference type="STRING" id="101091.A0A1C7N646"/>
    <dbReference type="InParanoid" id="A0A1C7N646"/>
    <dbReference type="OrthoDB" id="6499973at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050327">
        <property type="entry name" value="Proton-linked_MCT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11360:SF284">
        <property type="entry name" value="EG:103B4.3 PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11360">
        <property type="entry name" value="MONOCARBOXYLATE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="151"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="189"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="215"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="332"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="357"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="394"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="422"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="4">
        <location>
            <begin position="259"/>
            <end position="457"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OBZ84079.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="457" mass="49888" checksum="9FF620A06D0BA15C" modified="2016-11-30" version="1">MDNTKVSYMETATIDIAHQSNDYSEKTNNQSMVDRTGYISFSNCWIGNLNELLIHDSVTYGNQSILANLIDQLSISFRGVLQDYYEQHVFGKSGSSVVQLSLVGTFGNFALNVFSPIAQVLVSYFGTKTSVIIATFLSTSGLLLASQSNQIWHLMITQGLVFGAGGSIIFYIGMSSIQQSFSDHRRGGIALGIATSGSCMGGLIMPFVMTAINRQFGITVCYWVLGGLTCLLYMISCFLFKNVTEDKISEDCSLSTIELDVLKSLSFILWCTADIVIELSYYTPLFFLPSYATYLGMSDTQGSCLISVTASCNAIGRILSGYAADHIGHINTIIITCLFAGLSAFFIWAFAYNFPLLILFSIVFGFFGGAFVTLSPSTTAIVTGMDKFRSGYSIFLFVTVVAMFGPNFAGIIEASVQQEPFLVYKIFTGTGYLVGAGIMIVLKWRLCGSLTMLLKKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N6E7</accession>
    <name>A0A1C7N6E7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Putative ATP-dependent helicase hrq1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">hrq1</name>
        <name evidence="5" type="ORF">A0J61_07748</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000542">
        <property type="protein sequence ID" value="OBZ84196.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N6E7"/>
    <dbReference type="FunCoup" id="A0A1C7N6E7">
        <property type="interactions" value="374"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N6E7"/>
    <dbReference type="InParanoid" id="A0A1C7N6E7"/>
    <dbReference type="OrthoDB" id="18781at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043138">
        <property type="term" value="F:3'-5' DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008047">
        <property type="term" value="F:enzyme activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042162">
        <property type="term" value="F:telomeric DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042275">
        <property type="term" value="P:error-free postreplication DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036297">
        <property type="term" value="P:interstrand cross-link repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006289">
        <property type="term" value="P:nucleotide-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032204">
        <property type="term" value="P:regulation of telomere maintenance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032202">
        <property type="term" value="P:telomere assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd17923">
        <property type="entry name" value="DEXHc_Hrq1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18797">
        <property type="entry name" value="SF2_C_Hrq"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:001137">
        <property type="entry name" value="DEAD/DEAH box helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055227">
        <property type="entry name" value="HRQ1_WHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018973">
        <property type="entry name" value="MZB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47957">
        <property type="entry name" value="ATP-DEPENDENT HELICASE HRQ1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47957:SF3">
        <property type="entry name" value="ATP-DEPENDENT HELICASE HRQ1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09369">
        <property type="entry name" value="MZB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22982">
        <property type="entry name" value="WHD_HRQ1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0347">Helicase</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="3">
        <location>
            <begin position="243"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="4">
        <location>
            <begin position="465"/>
            <end position="619"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OBZ84196.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="948" mass="108002" checksum="5D1ABE5888366881" modified="2016-11-30" version="1">MPKRRATNDDDDIAAKKNRNELPEPLAHILQMFQQLNLFCAFCHAHLETSMTLEHIQKSIPGLTLDDLVGINVVMPGFVKLNMLSDQLVEVEFGKKLFPKTNNTSFHSTTKVGSNAVQKLIEQQNKLFTRSLTQFMRHCQNKHLDVKQHLKLQIDKNRPVFDYFDGLDDALFEQIDTPKSIQDIVQSLPLCHFYDNQLKDTTTFPKREAVYDPQDSLCLSDQIRSALNQYHIQQLYQHQSQAIQHIMNGKDVIVSTSTASGKSLIYQIPVIEQLLSDVAARAIYLFPTKALAQDQKRAFLNIIQHIPQLKPNMIATFDGDTPSDRRFDIRKHARVILTNPDMLHHAILPNSTLWLEFLFHLRYVVIDELHVYHGLFGTHVAWIMRRLRRLCAQLGNHHIQFISCSATIHEPDKHMKSLLGVDEVAVVDQDGAPHGQKEFIVWNPPLQIPSDPNSGRKSALVEGAHLFEYLIENNIRTIAFCKVRKSCELLMKQVRDNLIQKQRKDLVDKIASYRGGYTADQRRTIEQQMFDGELLGIIATNALELGINIGSLDAVLMVGVPWSISALWQQSGRSGRRNADSLSIVVCDNNPLDQYYANHPKDLLTKRPDTLGLDLENDMILANHLQCAAEESPIDSVQDQTYFGSLLPDLCHSLLTSIGNQLYRPDPKYRPYPSQYVSIRNMTDEEDAFVVVDVTGSQRSILEQVQIDRVGFELYEGAIFIHQGKTFLVEECNMDKKYARVHLVRVDWTTRQRDHTDVDILSTLSSKPIAQDKRVFFGKVKVVTVVFGYHRLDKRGRIMDTFETYMDPIVLEANGVWADVPRSVLNKLKELEIDPMAAIHSASHCLISLLPKLNLVVAARDLRTECKSPYATRTRPFRIAIYETHSNGTVAQQAYNFFDRLIEKGIEQIDQCSCEEGCPSCIHSTFCSEQNQVSSKKGAWIVLDSLRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-06-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N766</accession>
    <name>A0A1C7N766_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_08775</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000709">
        <property type="protein sequence ID" value="OBZ83174.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N766"/>
    <dbReference type="InParanoid" id="A0A1C7N766"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ83174.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="95" mass="10991" checksum="5C9338F8FAB06C74" modified="2016-11-30" version="1">MKGFLLHTVGPTYFESTSHIENYVFEANCLENPSYDVFHLNNCMFVLIRMEQCVVRSRGNSSPLFCFTEGNGEETLPYYEPFILILKRSLLNEIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N7E2</accession>
    <name>A0A1C7N7E2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Demethylmenaquinone methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">menG_8</name>
        <name evidence="6" type="ORF">A0J61_08708</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000697">
        <property type="protein sequence ID" value="OBZ83244.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N7E2"/>
    <dbReference type="FunCoup" id="A0A1C7N7E2">
        <property type="interactions" value="432"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N7E2"/>
    <dbReference type="InParanoid" id="A0A1C7N7E2"/>
    <dbReference type="OrthoDB" id="2013972at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041698">
        <property type="entry name" value="Methyltransf_25"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023576">
        <property type="entry name" value="UbiE/COQ5_MeTrFase_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43591:SF24">
        <property type="entry name" value="2-METHOXY-6-POLYPRENYL-1,4-BENZOQUINOL METHYLASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43591">
        <property type="entry name" value="METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13649">
        <property type="entry name" value="Methyltransf_25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01184">
        <property type="entry name" value="UBIE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 6" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2 6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransferase" evidence="5">
        <location>
            <begin position="113"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="12"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF13649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OBZ83244.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="332" mass="38249" checksum="30C67D0328155A11" modified="2016-11-30" version="1">MPFSVRQRNPQTKSATTSISKSSTTGGRDQARELFEDEEIGPSLEPKFPVQHKEFIEGRNYHKTTRPNEQFLPCDDEEIERLQINHLLFKKRSLFVTPYFSPVEHQLKTGIKVLDVGSGPAWWLTDMAKHYANSYFVGVDSVIHPTVPPTNCHLKLHDLTKKLPFPDNTFDFVTQHDALFRYSKSDWETMLPEIMRVVKPGGYIEFVEPSGVMQDIGPNMSIWMMRLTVSLQTRNINLKIASQLGSMLEEFKEIELIEDSHRSAPIGWYGKTGDIMLECLERLFDAIKPKICEDWSMSPAKYDKLVETASAECRDFRSWTNIHFTVARKKSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N7E6</accession>
    <name>A0A1C7N7E6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 9">Chromatin modification-related protein EAF6</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">meaf6</name>
        <name evidence="11" type="ORF">A0J61_07062</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histone H4 and H2A. The NuA4 complex is also involved in DNA repair.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Component of the NuA4 histone acetyltransferase complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the EAF6 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000458">
        <property type="protein sequence ID" value="OBZ84888.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N7E6"/>
    <dbReference type="FunCoup" id="A0A1C7N7E6">
        <property type="interactions" value="333"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N7E6"/>
    <dbReference type="InParanoid" id="A0A1C7N7E6"/>
    <dbReference type="OrthoDB" id="440324at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035267">
        <property type="term" value="C:NuA4 histone acetyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006325">
        <property type="term" value="P:chromatin organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015418">
        <property type="entry name" value="Eaf6"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13476">
        <property type="entry name" value="CHROMATIN MODIFICATION-RELATED PROTEIN MEAF6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09340">
        <property type="entry name" value="NuA4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 9" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="9" id="KW-0227">DNA damage</keyword>
    <keyword evidence="9" id="KW-0234">DNA repair</keyword>
    <keyword evidence="8 9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 9" id="KW-0804">Transcription</keyword>
    <keyword evidence="5 9" id="KW-0805">Transcription regulation</keyword>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="129"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="9"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="131"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="10">
        <location>
            <begin position="155"/>
            <end position="174"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010916"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00018504"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU368022"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="OBZ84888.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="185" mass="20732" checksum="533266BF9F45A694" modified="2016-11-30" version="1">MPDTTKEITTNPTPSSTTNTAQTSAPATSAGTAKETPAEPPQVTRQKYEEAKHELQALLARKKQVDTNLINLEHSIYLFEGSYLEDTQQNGNIIRGFDGYLTNRPDRRKPKFTELDRLFSLSSSTYQKALAQKEEKDQDSSQDDRSVGGSISARRDKKRKIKHDSNGIKKKRSSAGRDTEDELDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N7K6</accession>
    <name>A0A1C7N7K6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_06834</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000431">
        <property type="protein sequence ID" value="OBZ85120.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N7K6"/>
    <dbReference type="InParanoid" id="A0A1C7N7K6"/>
    <dbReference type="OrthoDB" id="2240924at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="458"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="496"/>
            <end position="517"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="504"/>
            <end position="517"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ85120.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="517" mass="57628" checksum="307863B9B688B33A" modified="2016-11-30" version="1">MVFCSSQDAQEMHQEKKPYIHPHDPFVEEEYEALIRAWKNQLVDHTPSSHNSDYIRFAWMRLMDHYLDQQWLDSKQMLQCAQAWSARDTLSLTEAVHTMNILSLKMMQRSLDARQEMLQALGDPGFMVSFGISSATGSNDRVSLAGSEEDDQEVHAPLFSKHESIPANRVEDEGIVTCRLGEPKHELQDEQSPKSKQNSDTMQARRLTLLVEQSKDMLPVRRRSRVLSFNSTPALSSNTKQKAYKLNRKYESFYHDAPSNWKETLISKQPDASSDSTSIFTSAHSEASSPIFQSEAQWKSWFLGDDAQPPPPVPISLTASPPSSTTAIIGTTVTTPPALPSITPSTSSVSELSRERSKPIIYAEEKVETDASVPAAYPLSSIRKLQQRPSLLTKSESSITAFRPISNNLAPRCQPLPIPLMMSDIVVPQASVSASVIQNGKTKITKSKSFPNKSALLSSKKFGSYSPPPPMPHQREQSHQQLSQFMTRVKKKVSLTKLFTGKKSSSSTSSSNSSDIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N8G5</accession>
    <name>A0A1C7N8G5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">Lysosomal dipeptide transporter MFSD1</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="16">Major facilitator superfamily domain-containing protein 1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="22" type="primary">MFSD1_0</name>
        <name evidence="22" type="ORF">A0J61_06523</name>
    </gene>
    <organism evidence="22 23">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="22 23" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="22 23">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="17">Lysosomal dipeptide uniporter that selectively exports lysine, arginine or histidine-containing dipeptides with a net positive charge from the lysosome lumen into the cytosol. Could play a role in a specific type of protein O-glycosylation indirectly regulating macrophages migration and tissue invasion. Also essential for liver homeostasis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>L-alanyl-L-lysine(out) = L-alanyl-L-lysine(in)</text>
            <dbReference type="Rhea" id="RHEA:79415"/>
            <dbReference type="ChEBI" id="CHEBI:192470"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>L-alpha-aminoacyl-L-arginine(out) = L-alpha-aminoacyl-L-arginine(in)</text>
            <dbReference type="Rhea" id="RHEA:79367"/>
            <dbReference type="ChEBI" id="CHEBI:229968"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>L-alpha-aminoacyl-L-histidine(out) = L-alpha-aminoacyl-L-histidine(in)</text>
            <dbReference type="Rhea" id="RHEA:79375"/>
            <dbReference type="ChEBI" id="CHEBI:229967"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>L-alpha-aminoacyl-L-lysine(out) = L-alpha-aminoacyl-L-lysine(in)</text>
            <dbReference type="Rhea" id="RHEA:79383"/>
            <dbReference type="ChEBI" id="CHEBI:229966"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>L-arginyl-L-alpha-amino acid(out) = L-arginyl-L-alpha-amino acid(in)</text>
            <dbReference type="Rhea" id="RHEA:79371"/>
            <dbReference type="ChEBI" id="CHEBI:84315"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>L-arginyl-glycine(out) = L-arginyl-glycine(in)</text>
            <dbReference type="Rhea" id="RHEA:79391"/>
            <dbReference type="ChEBI" id="CHEBI:229955"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-aspartyl-L-lysine(out) = L-aspartyl-L-lysine(in)</text>
            <dbReference type="Rhea" id="RHEA:79411"/>
            <dbReference type="ChEBI" id="CHEBI:229953"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>L-histidyl-L-alpha-amino acid(out) = L-histidyl-L-alpha-amino acid(in)</text>
            <dbReference type="Rhea" id="RHEA:79379"/>
            <dbReference type="ChEBI" id="CHEBI:229964"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>L-histidyl-glycine(out) = L-histidyl-glycine(in)</text>
            <dbReference type="Rhea" id="RHEA:79395"/>
            <dbReference type="ChEBI" id="CHEBI:229957"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>L-lysyl-L-alanine(out) = L-lysyl-L-alanine(in)</text>
            <dbReference type="Rhea" id="RHEA:79399"/>
            <dbReference type="ChEBI" id="CHEBI:229954"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>L-lysyl-L-alpha-amino acid(out) = L-lysyl-L-alpha-amino acid(in)</text>
            <dbReference type="Rhea" id="RHEA:79387"/>
            <dbReference type="ChEBI" id="CHEBI:229965"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>L-lysyl-L-lysine(out) = L-lysyl-L-lysine(in)</text>
            <dbReference type="Rhea" id="RHEA:79403"/>
            <dbReference type="ChEBI" id="CHEBI:229956"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>L-lysyl-glycine(out) = L-lysyl-glycine(in)</text>
            <dbReference type="Rhea" id="RHEA:79407"/>
            <dbReference type="ChEBI" id="CHEBI:191202"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="18">Homodimer. Interacts with lysosomal protein GLMP (via lumenal domain); the interaction starts while both proteins are still in the endoplasmic reticulum and is required for stabilization of MFSD1 in lysosomes but has no direct effect on its targeting to lysosomes or transporter activity.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="22">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000397">
        <property type="protein sequence ID" value="OBZ85425.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N8G5"/>
    <dbReference type="STRING" id="101091.A0A1C7N8G5"/>
    <dbReference type="InParanoid" id="A0A1C7N8G5"/>
    <dbReference type="OrthoDB" id="424834at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052187">
        <property type="entry name" value="MFSD1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23512">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23512:SF12">
        <property type="entry name" value="TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_4G00260)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
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    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="20" id="KW-0472">Membrane</keyword>
    <keyword evidence="23" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="20" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="20" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="20">
        <location>
            <begin position="59"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="20">
        <location>
            <begin position="98"/>
            <end position="117"/>
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    <feature type="transmembrane region" description="Helical" evidence="20">
        <location>
            <begin position="124"/>
            <end position="144"/>
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    <feature type="transmembrane region" description="Helical" evidence="20">
        <location>
            <begin position="150"/>
            <end position="171"/>
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    <feature type="transmembrane region" description="Helical" evidence="20">
        <location>
            <begin position="183"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="20">
        <location>
            <begin position="218"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="21">
        <location>
            <begin position="60"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="19">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="19">
        <location>
            <begin position="13"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00044876"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00044878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00044881"/>
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    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00044884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00044891"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00044893"/>
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    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00044898"/>
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    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00044899"/>
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        <source>
            <dbReference type="ARBA" id="ARBA00044903"/>
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        <source>
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        <source>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00044924"/>
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    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00044985"/>
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    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00045018"/>
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    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00045709"/>
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    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00046376"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="21">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="EMBL" id="OBZ85425.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="258" mass="27583" checksum="560685BC55B47266" modified="2016-11-30" version="1">MLSTKENAIDEQSPLLSPSSSTSAGCCSEANCCKKIAIEDDDDDPTCQLSKQPWKYKSIALLCAIFLAMGSHFAAHTLGAMKSTIKKEFGITNSQYGVLQSSVSIVNTVLPLAGGLFIDAFGTIPGSILTTVLIAFGNILVAASTSTTNLSMMILGRILYGIGSGTVVIVQETILSQWFQGRSLAAVIALMMTISRLSSFLAQATVVPIATWSGWYGYGFWFSAALCVASLVINLIYIGLLKTVLNLSDKERCRVQQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N8K6</accession>
    <name>A0A1C7N8K6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">DNA polymerase</fullName>
            <ecNumber evidence="12">2.7.7.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="primary">pola1</name>
        <name evidence="18" type="ORF">A0J61_06537</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18 19">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>DNA(n) + a 2'-deoxyribonucleoside 5'-triphosphate = DNA(n+1) + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:22508"/>
            <dbReference type="Rhea" id="RHEA-COMP:17339"/>
            <dbReference type="Rhea" id="RHEA-COMP:17340"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61560"/>
            <dbReference type="ChEBI" id="CHEBI:173112"/>
            <dbReference type="EC" id="2.7.7.7"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 12">Belongs to the DNA polymerase type-B family.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.7" evidence="12"/>
    <dbReference type="EMBL" id="LUGH01000399">
        <property type="protein sequence ID" value="OBZ85411.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N8K6"/>
    <dbReference type="InParanoid" id="A0A1C7N8K6"/>
    <dbReference type="OrthoDB" id="6755010at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005658">
        <property type="term" value="C:alpha DNA polymerase:primase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003682">
        <property type="term" value="F:chromatin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003688">
        <property type="term" value="F:DNA replication origin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003887">
        <property type="term" value="F:DNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006273">
        <property type="term" value="P:lagging strand elongation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006272">
        <property type="term" value="P:leading strand elongation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902975">
        <property type="term" value="P:mitotic DNA replication initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="entry name" value="DNA_polB_alpha_exo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd05532">
        <property type="entry name" value="POLBc_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.2820:FF:000001">
        <property type="entry name" value="DNA polymerase"/>
        <property type="match status" value="1"/>
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    <dbReference type="Gene3D" id="2.40.50.730">
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3200.20">
        <property type="entry name" value="DNA Polymerase alpha, zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="DNA polymerase family B, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Palm domain of DNA polymerase"/>
        <property type="match status" value="2"/>
    </dbReference>
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        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="DNA-dir_DNA_pol_B"/>
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        <property type="entry name" value="DNA-dir_DNA_pol_B_CS"/>
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        <property type="entry name" value="DNA-dir_DNA_pol_B_exonuc"/>
    </dbReference>
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        <property type="entry name" value="DNA-dir_DNA_pol_B_multi_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043502">
        <property type="entry name" value="DNA/RNA_pol_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042087">
        <property type="entry name" value="DNA_pol_B_thumb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023211">
        <property type="entry name" value="DNA_pol_palm_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038256">
        <property type="entry name" value="Pol_alpha_znc_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045846">
        <property type="entry name" value="POLBc_alpha"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015088">
        <property type="entry name" value="Znf_DNA-dir_DNA_pol_B_alpha"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00592">
        <property type="entry name" value="pol2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45861">
        <property type="entry name" value="DNA POLYMERASE ALPHA CATALYTIC SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45861:SF1">
        <property type="entry name" value="DNA POLYMERASE ALPHA CATALYTIC SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00136">
        <property type="entry name" value="DNA_pol_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03104">
        <property type="entry name" value="DNA_pol_B_exo1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08996">
        <property type="entry name" value="zf-DNA_Pol"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00106">
        <property type="entry name" value="DNAPOLB"/>
    </dbReference>
    <dbReference type="SMART" id="SM00486">
        <property type="entry name" value="POLBc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56672">
        <property type="entry name" value="DNA/RNA polymerases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00116">
        <property type="entry name" value="DNA_POLYMERASE_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 12" id="KW-0235">DNA replication</keyword>
    <keyword evidence="10 12" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="9 12" id="KW-0239">DNA-directed DNA polymerase</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 12" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="11" id="KW-0539">Nucleus</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="14" id="KW-0732">Signal</keyword>
    <keyword evidence="3 12" id="KW-0808">Transferase</keyword>
    <keyword evidence="8" id="KW-0862">Zinc</keyword>
    <keyword evidence="7" id="KW-0863">Zinc-finger</keyword>
    <feature type="signal peptide" evidence="14">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008889547" description="DNA polymerase" evidence="14">
        <location>
            <begin position="17"/>
            <end position="1538"/>
        </location>
    </feature>
    <feature type="domain" description="DNA-directed DNA polymerase family B exonuclease" evidence="16">
        <location>
            <begin position="567"/>
            <end position="812"/>
        </location>
    </feature>
    <feature type="domain" description="DNA-directed DNA polymerase family B multifunctional" evidence="15">
        <location>
            <begin position="878"/>
            <end position="1322"/>
        </location>
    </feature>
    <feature type="domain" description="Zinc finger DNA-directed DNA polymerase family B alpha" evidence="17">
        <location>
            <begin position="1367"/>
            <end position="1533"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="19"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="133"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="164"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="199"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="273"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="19"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="48"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="141"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="164"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="209"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="308"/>
            <end position="325"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU000442"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF00136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF03104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF08996"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="OBZ85411.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="1538" mass="175449" checksum="D11275FB98939336" modified="2016-11-30" version="1">MRFLSFLVYFISPAECMSHKRSNDELPPKEIPQKRQRNNQSEIERSDQAGTQLLDRQQGDTQEYSIAKSEEDAIESDDDVDQFILNNEILSILDNPHLSQAYSSQGIDSAVREELKTHLQNVVIDAGASNTNSQASFSIRNNSGSNSNHANSLSGTEIVFTESSKSQIADKSSIPDSESDENDVFYDAKEIDFGKEVSTEKQGVVGESPNLSFSVETQPESQGYQQQTTESNPPDHMTNSVTHSQEPRSVSLGVAVSEKEDWRKVVGELFDEIFDDPWTPMSNSSKTIDPIPSDDEQPSTEMPISTTENKEQSPDEDENWTRFMDDLFEDPTTPKSSEPTVSDHMSLDEEQSSAEVSRDTMENEMAIDEQSENEKNQEESDSTDLIEPQPVLHINTQVVPVHWEEDMAKSIRFTPQHLFEPAKFRPKMSSEKKAFDLELWWYDAYEDFNKGTVYLFGKSYNDKSNCYESCCVQLQGIQREIYILPRQYKTDDNGDQTNEKVSLDDVKNELALLLQRKGIESFQMQTCSRKYAFGATEIPAKATYIKLNYSYKDYELPTTLNGKTFSHIFGANTGPLEHWIVQRHIMGPCWIRVTDVLIADGSQSWCKLNTITTGIHTCTVIEQERTIPPLTILSLNAISYMNPYTDSNEIVAVSGFVRKNAAIDGADVTPIDATCFTFVRLLPKTEYTENMISAAKQASDHHIFLETTEKALLNGLINTIHRLDPDILVGHDFYGICLNLLLRRMKHLDIGHWHKIGRIRHRKWPKSVASSSSALLGESSFQERRLMTGRIVCDTFMASKDLIKSRSYDLTELASSQLHVVRHSIEPHQLKNYFNQDGDRFLLLLNHCLYDAFLAYQLMTKMNVLLLTKQLTNVSGNLWSHTLHGARLERNEYLLLHTFYQKGFVYPDKTLKEQKMLQFTDEALELEVSRKNPKNPRSGATTLLSGGLVLEPKIGLYDDYVLLLDFNSLYPTIMQEFNVCFTNPDLIGYNSSSIPSNQTELCVLPELVKKFVDQRKRVKKLMREPGISRSQKAKYEIQQMSLKLTANSMYGSLGSTVSRFQSKRLAAFITAKGREILRSTVNIAFDLGLDVIYGDTDSIMINTHQKKLMKAKAIGEGLKTHINRHHRLLEIDIDSIFRRTLLARKKKYAALAVSERLDGVWQESVQIKGLDLVRRDWCSLSREVSEEVLKLIFHHEDQETIVPAVYQYLQQVARKMEHEEYTIDSYIIRKQLTKLPQDYMNSKSNHHVTVAKSMRRAGQMVRVGDTVAYVMCKPSNPANTSKTGAPIPCTPKEVSDGNLSIDIRWYLQKQILPPVYRICQPIHGTDIKQLADQLNVDIDDLVDNLEDTTDKTSVTGYTCKNPDMLLLNDEECYNIMEPPSFICSYCSHTNPFLGPIQIEDGKIISGLTCVSCQLVMNKASVWCQLHQKLESLINQYYQRKWACNKNDCGFSTRDDIGVYCVEHHCDGKLIPEISDRSFYNRLCYFSKLFDCSKSLEQIPETAEDQVSQYQSDFLEIKQLVDQWIQRSGYRYLDVPWVT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N8V3</accession>
    <name>A0A1C7N8V3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_06456</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000390">
        <property type="protein sequence ID" value="OBZ85497.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N8V3"/>
    <dbReference type="STRING" id="101091.A0A1C7N8V3"/>
    <dbReference type="InParanoid" id="A0A1C7N8V3"/>
    <dbReference type="OrthoDB" id="2562743at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005929">
        <property type="term" value="C:cilium"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21974">
        <property type="entry name" value="RE15880P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21974:SF2">
        <property type="entry name" value="RE15880P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="407"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="31"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="159"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="440"/>
            <end position="450"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ85497.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="450" mass="51603" checksum="BDB0A21404FAE031" modified="2016-11-30" version="1">MSTVQCIQDQGPYFRKLSNELKTESSVDRDLEQVKYEIQRLQDAIQQRRQEIEALEQNSKKEFEGVRKMRHLSFRSAAATISGKKKALTARDEAKYQLAFENEQRSKRAMEELQVAYDQAIVKNQALTQQKQHFTNVRFQYESLLQQIFADEDPAFPQEQQLRGELTNYEEQQRMAKRDTNRFKNAERALSEALVDIKKAIRITDTVIHYMPFEFFGGPAIDAQQIAYLEAAKRKIWQIQHHFNLARTELPEIPYPQTLDVVTNNTLMTMQFNLHYVELAWKAKASQCFGVLATAYRNAQNSLTWVKQYKEYATGALIRLEEAIVNVKRSLEQERCRIVEDVLAGRPTTEASRSTAIPPPVYEAPPSIEASQHDRLHSDPLPQVPAHIMAPSPTYSHLPLTYKSSASPSFLEDLEPTQPSSSTAHPPQPIAPLTEPYVSHNVNNPFNKQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N968</accession>
    <name>A0A1C7N968_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">SAM50-like protein SPAC17C9.06</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">A0J61_06481</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion outer membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SAM50/omp85 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000393">
        <property type="protein sequence ID" value="OBZ85468.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N968"/>
    <dbReference type="FunCoup" id="A0A1C7N968">
        <property type="interactions" value="513"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N968"/>
    <dbReference type="InParanoid" id="A0A1C7N968"/>
    <dbReference type="OrthoDB" id="1724197at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005741">
        <property type="term" value="C:mitochondrial outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045040">
        <property type="term" value="P:protein insertion into mitochondrial outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.160.50">
        <property type="entry name" value="membrane protein fhac: a member of the omp85/tpsb transporter family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000184">
        <property type="entry name" value="Bac_surfAg_D15"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039910">
        <property type="entry name" value="D15-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12815:SF18">
        <property type="entry name" value="SORTING AND ASSEMBLY MACHINERY COMPONENT 50 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12815">
        <property type="entry name" value="SORTING AND ASSEMBLY MACHINERY SAMM50 PROTEIN FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01103">
        <property type="entry name" value="Omp85"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1134">Transmembrane beta strand</keyword>
    <feature type="domain" description="Bacterial surface antigen (D15)" evidence="6">
        <location>
            <begin position="148"/>
            <end position="483"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004374"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022452"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OBZ85468.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="484" mass="53522" checksum="AF315402FD645786" modified="2016-11-30" version="1">MEENKQVPIEQDIQQQREFQAEASRRLFSLLDQTASQKAHVNSVTILGTKTTRARFLETATKEILEAKTYAEVINISQQIAEKLQRFDIFEEPVQVLLDSASESDPLAAPDSINVVLQAKEKSRVFIKTGTEIGNNEGNMNGSVTIRNVFGGAELLETVASFGTRNSSAFQFNFSRPVQASPDSRLELNAHRIVCNNTLASSYEELARGLGLRYKTLSRFGFHELSYDLTWRSIDRVSPNASLSIRKEVGESLKSSIIHTFVRERRDDMLLPANGHYVRLVNELAGMLGLGNAHFFKTELETQFCKQFGGGQFLVDSETDELLGVHPGIVWSTTFRAGFLANLSQENARKAVTVSDRFMLGGPLSVRGFRTAGIGPRDYKDALGGDLYWAGGLSLIAPLPKWESKPLRAHAFVNAGTNVPWVMSKSIEDTAQSLMQSPSVSAGFGLIYRHSIARIELNYCVPLTAARGDQIKRGLQLGVGINFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N9L5</accession>
    <name>A0A1C7N9L5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">N-acetyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">A0J61_06146</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000357">
        <property type="protein sequence ID" value="OBZ85805.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N9L5"/>
    <dbReference type="InParanoid" id="A0A1C7N9L5"/>
    <dbReference type="OrthoDB" id="2204056at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04301">
        <property type="entry name" value="NAT_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050769">
        <property type="entry name" value="NAT_camello-type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13947">
        <property type="entry name" value="GNAT FAMILY N-ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13947:SF37">
        <property type="entry name" value="LD18367P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="51"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="91"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="domain" description="N-acetyltransferase" evidence="3">
        <location>
            <begin position="181"/>
            <end position="318"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OBZ85805.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="336" mass="39181" checksum="D48FB8CE8273EF3F" modified="2016-11-30" version="1">MTKKKSTQPTQEPAKPKVVLRTYRDTDYEQVEYLFRATQVPLVYESIRSKIWAPLTWVIWFVGYTAILYTIPFVTDRVLGRDVPLWAMTTIKVFSTFWWGVIAFVALFVVSDRVEMQNRVDEAMANDLRDPDLYYLNYTLQDGKKVRKPEEEQVPSHFWVLSVDDQVCGMLGLSCYAEDMEDQRTSLPVGWKQFVVALLELVRLSVPSFLEKGRPNTSDYQLKDKKRIFAHQQIPKTATITRWAIRSDLQACGLSTLLINRAISWCKERDINRVYALVNESNMAAEQVLTRRHGFVMVKKFKKGLFGQFEKLLACRVNEWIEKHGEQTRKAFKKSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NA31</accession>
    <name>A0A1C7NA31_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_05958</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000339">
        <property type="protein sequence ID" value="OBZ85992.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NA31"/>
    <dbReference type="STRING" id="101091.A0A1C7NA31"/>
    <dbReference type="InParanoid" id="A0A1C7NA31"/>
    <dbReference type="OrthoDB" id="2289893at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="20"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="123"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="252"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="305"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="527"/>
            <end position="546"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="595"/>
            <end position="745"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="24"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="137"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="179"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="202"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="268"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="326"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="358"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="396"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="451"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="469"/>
            <end position="512"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="596"/>
            <end position="612"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="643"/>
            <end position="661"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="662"/>
            <end position="685"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="690"/>
            <end position="710"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="726"/>
            <end position="738"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="745"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ85992.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="745" mass="82085" checksum="C5CDAB9B0C63BD02" modified="2016-11-30" version="1" fragment="single">MSYNNWQQSEKHLPKVFKRLGRSTPHNNAGTDHPSSTAAPVDRGFKIAGHYQNNTGVQYANHHYHYYNHAASHSIPTGPAAHAIPTGPAAHTIPTGPAQRHHHHRHLSSEANHRTNYIKHIHQQDTMPTRDYYSPTPIMSPTTSQHSAYHGHSPTNHKRIPTENVDYHGNNTDSNLPVSPASSASSSPGFSFVKNNDVPKEPSQQPGRSSFSFVRSNAPTPYPPSSPYYLEPIHQMSPASVTPVIPTGPASSTYPSIEVTVPKKKKSASPEKKTQDNENDNGHAENDTPVMNERDRLAKNIQITVSRPSLAAESNTEKDAQPQNITSATTTLDQDTTNSTMFQPINRKVIVKGVENKVNPSTRSSPPCTTEKTQRSRSPPSSRKRHRSTSPGSSSDEEKAPFPRGKADHYVPNYNRRPLPPQFRQERNKKKVQANNGDKKSHDVTPGTHPVSLSKTTNKGKQGTHEPSMPSQPKLLSTSPVHNKASQNQPKETEKNTVPSLQKQNKPSSDASSMAHRIITMNNTIVKPNQRVETTEPKLKTEPVNAGTTSLNALSNKLASAQPTSTLQQKKAEEEAIKTNQNAVCSDAVASEVVSGKSTSSDHNSGSKQTTALPVANHALVKDSTNGAERKRRRVFSDNPSVDIKDSSVKKHKSDEPKELQQDATRFSSKNQLTPSSLKAPNLNQLRAAALEKREEREHQHQLRLRQLDIDDRDDIVMDVTPPSNPSFDPSEQQQTAPSKKKNPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NAC2</accession>
    <name>A0A1C7NAC2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_05863</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000330">
        <property type="protein sequence ID" value="OBZ86082.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NAC2"/>
    <dbReference type="STRING" id="101091.A0A1C7NAC2"/>
    <dbReference type="InParanoid" id="A0A1C7NAC2"/>
    <dbReference type="OrthoDB" id="8121869at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ86082.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="163" mass="19113" checksum="7C81EBF9C5425C75" modified="2016-11-30" version="1">MAKDINGQLKCTKRFPKAIIEETVLNENEHPIYKRSVTVESPYTMPDPLRRVNNHIDINANWVVSYNPFLFEYKVYEEDPIVTSLALHLSNEQPLECRKSICDDLGHKFRQMFPKVQLYLLTDEAIFYNGQASMDYGFYLIEEKLKGFGRSFDDFILPNVKHD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NAD0</accession>
    <name>A0A1C7NAD0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_06368</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000381">
        <property type="protein sequence ID" value="OBZ85586.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NAD0"/>
    <dbReference type="InParanoid" id="A0A1C7NAD0"/>
    <dbReference type="OrthoDB" id="2555519at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="74"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="204"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="89"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="100"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="212"/>
            <end position="225"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ85586.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="225" mass="25818" checksum="B152FC86DE9FF222" modified="2016-11-30" version="1">MNFSANAYKTILRSNTLKSFHSLRLSNNPTSSHSPHYVVQHKSISEPSFDPYHSRASMQHYNQTVKQHSYIHPSNCMLQRKSMDPNDSSTEEEEEEDMSDSQSSSSESTLSTKIADLKMANKSLLTINKVLESTVRQQAKHIAFLQDVHLYLHERSFSYQAIESEQSNQLDRLERKIEMMIQEGERALAYQVGVSDCVLASNGDHNPLLRSSHTHSKHRSRKRLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-06-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NAE4</accession>
    <name>A0A1C7NAE4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_06021</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000344">
        <property type="protein sequence ID" value="OBZ85928.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NAE4"/>
    <dbReference type="InParanoid" id="A0A1C7NAE4"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ85928.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="70" mass="7955" checksum="25FE9CBC2D0921BC" modified="2016-11-30" version="1">MVVQIKICLMQTIRYIFDLSHRRSIQNEAVENLNSQTCSSITTVTKKALGARTYAAHVLENTKSKEDSRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NB41</accession>
    <name>A0A1C7NB41_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="9">DNA topoisomerase 2-associated protein pat1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">A0J61_05616</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
            <location evidence="2">P-body</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the PAT1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000308">
        <property type="protein sequence ID" value="OBZ86342.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NB41"/>
    <dbReference type="FunCoup" id="A0A1C7NB41">
        <property type="interactions" value="176"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NB41"/>
    <dbReference type="InParanoid" id="A0A1C7NB41"/>
    <dbReference type="OrthoDB" id="74835at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000932">
        <property type="term" value="C:P-body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016853">
        <property type="term" value="F:isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000290">
        <property type="term" value="P:deadenylation-dependent decapping of nuclear-transcribed mRNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033962">
        <property type="term" value="P:P-body assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039900">
        <property type="entry name" value="Pat1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019167">
        <property type="entry name" value="PAT1_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21551:SF0">
        <property type="entry name" value="PROTEIN ASSOCIATED WITH TOPO II RELATED-1, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21551">
        <property type="entry name" value="TOPOISOMERASE II-ASSOCIATED PROTEIN PAT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09770">
        <property type="entry name" value="PAT1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9" id="KW-0413">Isomerase</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="mRNA decay factor PAT1" evidence="8">
        <location>
            <begin position="4"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="domain" description="mRNA decay factor PAT1" evidence="8">
        <location>
            <begin position="186"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="domain" description="mRNA decay factor PAT1" evidence="8">
        <location>
            <begin position="526"/>
            <end position="884"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="120"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="168"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="284"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="469"/>
            <end position="509"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="566"/>
            <end position="597"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="172"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="192"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="219"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="292"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="474"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="497"/>
            <end position="509"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="577"/>
            <end position="597"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009138"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF09770"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OBZ86342.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="891" mass="99293" checksum="39668FB446670AC7" modified="2016-11-30" version="1">MGDSFFGFNTNLPPLSEEEMHALTEQGKQNNKALEHSQAYDHTEAVYDFAALRHELGVDDQEHEEIHDGLGDQLIEEGDDNNMLTFGDAPIDQDFDFSGNTQRFQAGISEEEAFFVKRKHHDESQAHQGGFRNPWAVAPVRQSPSGIGRSFGEASPMATSKSIWGNFGGGLSPSSQSSLSPFSSANRQAVRPQQQPQQPQQQPVPPFMSPTISAGYPLQQQQQQQQQQQQRRPVTLEDIEADIQRQQAAHRYRGNNEPLSTAAPQPPIPNGKTLSLAELEAVLAGGGPMPPQQQQQQQQQPQAPPQPQQPFGYPATQPDPMQLLAMKQQQELKEQQLSVAREVKRRELQRKSQYDGLMTQHDKDVVNRIQLSQLASGDPYADDFYYQVYTTLRHRPGMPLQPNMVAAHHNSGNNEGNRNGRGRRDDNMMQRMQQQLQRIVNDAKRRPKQTQVSLEGALGKITSLTVRNPRQVLQVPSANTVHHTSGDSNNTKAESGNSTASNLSASATSAPTAANASSIMTTNDANAMHATSTSGISDHAHKSAAYDKRQVLKMTEDMYTTVLEIEEMRRQGPPRTEQQDTDHSEEQQQQQDQKKDSAEIFNEKLSAKVEKLWKSLRLTEHSESPFLIALLAIAKGKKLIPRIVRQLNHDQNLALLTVLIVHFSKLQVCRHVIYPGTAVANVDEAKKQAFVLFDEVELFMNATAPHLLAFIAEAPIRIVIGLLQLFLEKNEIGLVAQTKPGLAFLTMLLSRAEILKQGGGSLHGLPPPTPEEVGRWQELYNNLFASLKGRYLSIFPSLYYLVPLNPNTPMMQLSLAVDDMYVWQFLAAMAVGASMDQQHILVTEVRDRVMDNIVLAKRNRLPLDQASHRISNVNLFLHALGLDASQVSVPM</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NB78</accession>
    <name>A0A1C7NB78_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Luciferin 4-monooxygenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">LUCI</name>
        <name evidence="5" type="ORF">A0J61_05558</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ATP-dependent AMP-binding enzyme family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000303">
        <property type="protein sequence ID" value="OBZ86392.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NB78"/>
    <dbReference type="STRING" id="101091.A0A1C7NB78"/>
    <dbReference type="InParanoid" id="A0A1C7NB78"/>
    <dbReference type="OrthoDB" id="10253115at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016405">
        <property type="term" value="F:CoA-ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="entry name" value="N-terminal domain of ligase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025110">
        <property type="entry name" value="AMP-bd_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_synth/lig_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24096:SF149">
        <property type="entry name" value="AMP-BINDING DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24096">
        <property type="entry name" value="LONG-CHAIN-FATTY-ACID--COA LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13193">
        <property type="entry name" value="AMP-binding_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56801">
        <property type="entry name" value="Acetyl-CoA synthetase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0436">Ligase</keyword>
    <keyword evidence="5" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AMP-dependent synthetase/ligase" evidence="3">
        <location>
            <begin position="26"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="domain" description="AMP-binding enzyme C-terminal" evidence="4">
        <location>
            <begin position="444"/>
            <end position="524"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF13193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OBZ86392.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="541" mass="60227" checksum="14D394877B0BC8D5" modified="2016-11-30" version="1">MTIESKNLTPQSLNGSVYDMLFNRSSDIDPNKPCFVDAEDQSQMLTFCDVKQLILKFAAALKRTLSDFSKGDVVAFYSANNATYAAAVHGPSVIGGSSALVDCTNDVPDLVESLKLVKAKVIIADEKKVHNALDAARLLSIPKENVFVFGNRDIHGARSFNKTFLCHNEITNPVHFDPEDSDAKPCYFYFTSGTTGGKKKAVVVSYRMIYNAVVVKKFPFHQNFRMLCGKHFHHASTLYFTMCAFPFHGLTTYFMKEFTFENYLKAVQDCSLNFIFVSPSIGASLVKEPIVDNYDISSLQCIAFGGSSISPLISEAIFKKFKIPILNIYGTSEIIRCFASDPKAALAGEVGSLEIGCECKLIDDNGQATLIEVGSDIVGELYIKGPTMTPGYYNDPVANTEAFVDGWFKTGDLFKLTEKGNAIFVDRVKNIIQYKTFRIVPQDIENVLLLHPLIVDCAVVGIYCKTECTWLPRAYVVLARVLNPNLSKIEEETQNLIETKLSNEMQLRGGFYFVKRLPKTATGKIKRYRLCTNDAHIVYSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NBF6</accession>
    <name>A0A1C7NBF6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_07282</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000483">
        <property type="protein sequence ID" value="OBZ84674.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NBF6"/>
    <dbReference type="STRING" id="101091.A0A1C7NBF6"/>
    <dbReference type="InParanoid" id="A0A1C7NBF6"/>
    <dbReference type="OrthoDB" id="2282785at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="551"/>
            <end position="574"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="555"/>
            <end position="572"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ84674.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="601" mass="69198" checksum="8724F4328E05D4D5" modified="2016-11-30" version="1">MADITEEAAWESVKDSLYLSAYWMNQIVDDWNVIDYFIKLMEKEPTMDKRMATAKIMNDLELIQTALIHIPKIKSKTTTMISLIRKKSQVVSTFWEKHTLELEMVSLDHKLYVRKTQALLEEEALNRSTIKRKQNNSSLVPKSSKKRGVDIQIHQIEYDSITVPGSDVSLATIIKRKAVEFHEKFVLSPDDLTPRQRKIMSAGLSSILDLTDQSFGSQRSIFTAEQWDYINVYFEERLIIKRHALDDDISNTIKIVQNTLRLSNDYECAIEYVDKLKQKYSKSDKLKATAFKIIKHILKTMDNYGHLLHEKKVVRENEYMRLIWSYLLELLFPPKGIVRVVTGESENAYSTESKKEQYPLAKSVHGFKIDIRLVVEVDDEEEIDLAVGECAKRNNDNKAIKDNAKLLRECKDSIDRLINTLKDTNDDVMSYMIQITGSSCALSTMHLAANGLYVAKHRFTFNMPHRFDDLSSLSETLAQLLTMKKEVQSVADKIIKERTKTHTAEVSFNRQKAPMINDRLSWLRSTWYSPPGDQVSTVPIRCFGSPPAPRFIKEASTSTEQPEPQQTGQSTADKYGWVKLDSGEHYNIYTKETLSKHPLDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NBL1</accession>
    <name>A0A1C7NBL1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Large ribosomal subunit protein mL44</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">mrpl3</name>
        <name evidence="11" type="ORF">A0J61_05479</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the ribonuclease III family. Mitochondrion-specific ribosomal protein mL44 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000296">
        <property type="protein sequence ID" value="OBZ86473.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NBL1"/>
    <dbReference type="FunCoup" id="A0A1C7NBL1">
        <property type="interactions" value="244"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NBL1"/>
    <dbReference type="InParanoid" id="A0A1C7NBL1"/>
    <dbReference type="OrthoDB" id="67027at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003725">
        <property type="term" value="F:double-stranded RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004525">
        <property type="term" value="F:ribonuclease III activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006396">
        <property type="term" value="P:RNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd19873">
        <property type="entry name" value="DSRM_MRPL3_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00593">
        <property type="entry name" value="RIBOc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1520.10">
        <property type="entry name" value="Ribonuclease III domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014720">
        <property type="entry name" value="dsRBD_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044443">
        <property type="entry name" value="Ribosomal_mL44_DSRM_fung"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044444">
        <property type="entry name" value="Ribosomal_mL44_DSRM_metazoa"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000999">
        <property type="entry name" value="RNase_III_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036389">
        <property type="entry name" value="RNase_III_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11207:SF32">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN ML44"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11207">
        <property type="entry name" value="RIBONUCLEASE III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22892">
        <property type="entry name" value="DSRM_MRPL44"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14622">
        <property type="entry name" value="Ribonucleas_3_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00358">
        <property type="entry name" value="DSRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00535">
        <property type="entry name" value="RIBOc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54768">
        <property type="entry name" value="dsRNA-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69065">
        <property type="entry name" value="RNase III domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50137">
        <property type="entry name" value="DS_RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50142">
        <property type="entry name" value="RNASE_3_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 11" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="2 8" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RNase III" evidence="10">
        <location>
            <begin position="50"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="domain" description="DRBM" evidence="9">
        <location>
            <begin position="196"/>
            <end position="266"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00024034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00035187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50142"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="OBZ86473.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="296" mass="32494" checksum="74EE626ADFA3AF52" modified="2016-11-30" version="1">MLRNFTKTKAMSTKTLAAMKTVPRVTFASIHHQPIYTQQDDQKLAPIVALGARLGLTIDTSVLKQALTHKSVSDANNNATLEYVGKKVTGLFATEYLHLKYPSLHPDAFTTTLSAYLCNKSIAKVASEVGLQHTIEWKAPEDNSVRLGHSTVMADCFNALVGALYQEQGQEAAKKFVHDFILSREYDVRPSIKVKEPKRHLTALLKQLNKEPATSRLVSETGRASSAPVFVVGVFSGEEKLGEGFGSSLKMAEFRACQDALISFYGQEQKDFTLPSDADRVDKYVASPLGNTQAIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NBQ7</accession>
    <name>A0A1C7NBQ7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_05408</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000290">
        <property type="protein sequence ID" value="OBZ86542.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NBQ7"/>
    <dbReference type="STRING" id="101091.A0A1C7NBQ7"/>
    <dbReference type="InParanoid" id="A0A1C7NBQ7"/>
    <dbReference type="OrthoDB" id="2228700at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008889600" evidence="1">
        <location>
            <begin position="20"/>
            <end position="163"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ86542.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="163" mass="17800" checksum="EF8CE018420CA8EF" modified="2016-11-30" version="1">MKWTCIPFLFSLVVAYTELKNIEAKEDVMESAELSSGGMLAQDYYPAVALAEFTGPNIIGEFHFVQDSLGDTVATGAFQKGLSPGQHYLFKFYDGPNCKRLGKVVVEHDFENLLGLSTGGTVPIQEKLDSVHLTGVDGLMGLPWVLSDGRRDLACVLLKKNSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NBV0</accession>
    <name>A0A1C7NBV0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Peroxisomal adenine nucleotide transporter 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">ANT1</name>
        <name evidence="12" type="ORF">A0J61_05703</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000316">
        <property type="protein sequence ID" value="OBZ86239.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NBV0"/>
    <dbReference type="STRING" id="101091.A0A1C7NBV0"/>
    <dbReference type="InParanoid" id="A0A1C7NBV0"/>
    <dbReference type="OrthoDB" id="446044at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031966">
        <property type="term" value="C:mitochondrial membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005778">
        <property type="term" value="C:peroxisomal membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015217">
        <property type="term" value="F:ADP transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015867">
        <property type="term" value="P:ATP transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006635">
        <property type="term" value="P:fatty acid beta-oxidation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007031">
        <property type="term" value="P:peroxisome organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002067">
        <property type="entry name" value="MCP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052217">
        <property type="entry name" value="Mito/Peroxisomal_Carrier"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45939:SF1">
        <property type="entry name" value="MITOCHONDRIAL THIAMINE PYROPHOSPHATE CARRIER 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45939">
        <property type="entry name" value="PEROXISOMAL MEMBRANE PROTEIN PMP34-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00926">
        <property type="entry name" value="MITOCARRIER"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 9 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 10" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="68"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="109"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="9">
        <location>
            <begin position="6"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="9">
        <location>
            <begin position="109"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="9">
        <location>
            <begin position="202"/>
            <end position="294"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="OBZ86239.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="311" mass="34152" checksum="2AD54C54A190B3A1" modified="2016-11-30" version="1">MSKASLPPVGHAVAGSASAMFALTLIYPLDIIKTRIQVQTKRESDEDEHYTSVMDGIQQIMQKEGLSGLYAGLGSSLIGTASTNFTYFYCYSFLRENYNRRYNPRGGTLSTALELVLGAAAGALTTLITTPVSVITTRQQTLPANERQGVLETCQSIIKEEGVQGLWRGIQPSLLLCVNPAITYGSFEKIKQIVTQVLKLPLTPGVNFLVGALSKTLATVITYPYIMAKVRLQWKPSKEMKDKIVAYKGSVDVLTRVLKTEGFFGWYKGMSTQITKAVLSQALLFMMKDIFTNYTVLAYALIKASQKAKSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NCI1</accession>
    <name>A0A1C7NCI1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">C-type lectin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_05125</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000269">
        <property type="protein sequence ID" value="OBZ86825.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NCI1"/>
    <dbReference type="InParanoid" id="A0A1C7NCI1"/>
    <dbReference type="OrthoDB" id="2251369at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00037">
        <property type="entry name" value="CLECT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016187">
        <property type="entry name" value="CTDL_fold"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56436">
        <property type="entry name" value="C-type lectin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008889615" description="C-type lectin domain-containing protein" evidence="2">
        <location>
            <begin position="21"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="135"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="153"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="358"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ86825.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="358" mass="37552" checksum="9EC5DDFADB33F7B2" modified="2016-11-30" version="1" fragment="single">MAPRILTAALLAGMIVPSLAQNNESGFVCDYPGSDGYYFAKNLTFWDMANDSCGSAGVLASITNRNFEIATDLVRNCIGDNAAAWIGTWDYTAANPQVRKCLTLYVGDEDDGGGINVDCGNRRYAFCRRRPERINGPEYPPYLSPTDSGNGQASTSTTNTNTNTNTNTSPNTNPASTRTVTRDVTYTDVATITSTATTTSVSTAVDVTTITETSVATSTAYNATYIYSPIPPVYNTTLLAELLSEAQLLYDELFGVLGQAQNTTGILSELLSDATTAIGTISDLLGNATATSGNLTELIDNATTIIDALNNATANANNVSGVLDSANQNALGVIDTLNNLANSTADTVTGLLSDVTNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NCS0</accession>
    <name>A0A1C7NCS0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Drebrin-like protein B</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">dbnl-b</name>
        <name evidence="8" type="ORF">A0J61_05063</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the actin-binding proteins ADF family. Coactosin subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000263">
        <property type="protein sequence ID" value="OBZ86895.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NCS0"/>
    <dbReference type="STRING" id="101091.A0A1C7NCS0"/>
    <dbReference type="InParanoid" id="A0A1C7NCS0"/>
    <dbReference type="OrthoDB" id="5971719at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005884">
        <property type="term" value="C:actin filament"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030864">
        <property type="term" value="C:cortical actin cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030427">
        <property type="term" value="C:site of polarized growth"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051015">
        <property type="term" value="F:actin filament binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030833">
        <property type="term" value="P:regulation of actin filament polymerization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd11281">
        <property type="entry name" value="ADF_drebrin_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.20.10:FF:000018">
        <property type="entry name" value="Coactosin-like 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.20.10">
        <property type="entry name" value="Severin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002108">
        <property type="entry name" value="ADF-H"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029006">
        <property type="entry name" value="ADF-H/Gelsolin-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10829">
        <property type="entry name" value="CORTACTIN AND DREBRIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10829:SF25">
        <property type="entry name" value="DREBRIN-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00241">
        <property type="entry name" value="Cofilin_ADF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00102">
        <property type="entry name" value="ADF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55753">
        <property type="entry name" value="Actin depolymerizing proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51263">
        <property type="entry name" value="ADF_H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0009">Actin-binding</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ADF-H" evidence="7">
        <location>
            <begin position="6"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="204"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="219"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="239"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="250"/>
            <end position="277"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51263"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OBZ86895.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="277" mass="31350" checksum="7338D7DC3CFC32FF" modified="2016-11-30" version="1">MSHHVNFSTHGKELDAAYQAVISEQDDTNWLIYAYDKGTYDLRVQATGDGGLEELSDEFSDGKVQFAYAKVIDPNTELPKFVFIGWCGSGVPELRKAFFNSQLSDVSKFFKSFHVQINARDEADVEPALIMKRVSESSGAKYSVHKEAAKPQPRVAPVGSVYKKEEIPDIAAMQRQSMTKENAPTPVGTNYTPVQTAPKKLEQRWNAAQNQDSGASAVRAERERYEREVVEREKEKARQFTSHQASDNTSLREEAEARRRQEEEEQRQQRAETAKRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7ND42</accession>
    <name>A0A1C7ND42_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Oxidoreductase HTATIP2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">HTATIP2</name>
        <name evidence="4" type="ORF">A0J61_05006</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion outer membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the FMP52 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000258">
        <property type="protein sequence ID" value="OBZ86948.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7ND42"/>
    <dbReference type="STRING" id="101091.A0A1C7ND42"/>
    <dbReference type="InParanoid" id="A0A1C7ND42"/>
    <dbReference type="OrthoDB" id="430436at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005741">
        <property type="term" value="C:mitochondrial outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051170">
        <property type="term" value="P:import into nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016040">
        <property type="entry name" value="NAD(P)-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14097">
        <property type="entry name" value="OXIDOREDUCTASE HTATIP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14097:SF7">
        <property type="entry name" value="OXIDOREDUCTASE HTATIP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13460">
        <property type="entry name" value="NAD_binding_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD(P)-binding" evidence="3">
        <location>
            <begin position="10"/>
            <end position="166"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OBZ86948.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="243" mass="26321" checksum="3CEE0300FBE364FB" modified="2016-11-30" version="1">MSNPTAMIFGATGAVGKEVLKDLLTTGKYSKVVSVGRRTVELDSAIPQDKLEQKVVDFDNLEADKSIFKGVSDVFCCLGTTRAAAGSAENFVKIDQTYVLNSAKLIAEENKPSDDALAPVHFLYCSSTGANKDSMFLYIKTKGQTEEALKETGFEKVSIFQPGLLEIVDPRPTTRWGERFALAIVPPLNRMFNLHSSVPVTTVAKAMHHVAENKDIKAKSSSQSVIGSLVSVFSTAEIEDIGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NDE2</accession>
    <name>A0A1C7NDE2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Actin-2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">ACT2</name>
        <name evidence="10" type="ORF">A0J61_05164</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
            <location evidence="2">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 9">Belongs to the actin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000272">
        <property type="protein sequence ID" value="OBZ86779.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NDE2"/>
    <dbReference type="FunCoup" id="A0A1C7NDE2">
        <property type="interactions" value="256"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NDE2"/>
    <dbReference type="InParanoid" id="A0A1C7NDE2"/>
    <dbReference type="OrthoDB" id="5132116at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051286">
        <property type="term" value="C:cell tip"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005856">
        <property type="term" value="C:cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030427">
        <property type="term" value="C:site of polarized growth"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd10224">
        <property type="entry name" value="ASKHA_NBD_actin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.40:FF:000131">
        <property type="entry name" value="Actin, alpha skeletal muscle"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.40:FF:000291">
        <property type="entry name" value="Actin, alpha skeletal muscle"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.640.10:FF:000001">
        <property type="entry name" value="Actin, muscle"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.40:FF:000058">
        <property type="entry name" value="Putative actin-related protein 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.640.10">
        <property type="entry name" value="Actin, Chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004000">
        <property type="entry name" value="Actin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020902">
        <property type="entry name" value="Actin/actin-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004001">
        <property type="entry name" value="Actin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11937">
        <property type="entry name" value="ACTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00022">
        <property type="entry name" value="Actin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00190">
        <property type="entry name" value="ACTIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00268">
        <property type="entry name" value="ACTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00406">
        <property type="entry name" value="ACTINS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00432">
        <property type="entry name" value="ACTINS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01132">
        <property type="entry name" value="ACTINS_ACT_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003520"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006752"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00049360"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU000487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OBZ86779.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="375" mass="41765" checksum="F5F89D33CDDE178E" modified="2016-11-30" version="1">MEDEVAALVIDNGSGMCKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDSYVGDEAQSKRGILTLRYPIEHGIVTNWDDMEKIWHHTFYNELRVAPEEHPVLLTEAPLNPKSNREKMTQIMFETFNAPAFYVAIQAVLSLYASGRTTGIVLDSGDGVTHTVPIYEGYALPHAILRLDMAGRDLTDYLMRILAERGHSFTTTAEREIVRDIKEKLCYVALDFEQEMQTAAQSSALEKSYELPDGQVITVGNERFRAPEALFQPALLGLESVGIHETTYNSIMKCDVDIRKDLYSNIVMSGGTTMYPGIADRMQKEITALAPSSMKIKIVAPPERKYSVWIGGSILASLSTFQQMWISKQEYDESGPSIVHRKCF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NDJ4</accession>
    <name>A0A1C7NDJ4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Paired amphipathic helix protein Sin3b</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">Sin3b</name>
        <name evidence="10" type="ORF">A0J61_05320</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000284">
        <property type="protein sequence ID" value="OBZ86626.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NDJ4"/>
    <dbReference type="STRING" id="101091.A0A1C7NDJ4"/>
    <dbReference type="InParanoid" id="A0A1C7NDJ4"/>
    <dbReference type="OrthoDB" id="10265969at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033698">
        <property type="term" value="C:Rpd3L complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003714">
        <property type="term" value="F:transcription corepressor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000122">
        <property type="term" value="P:negative regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010628">
        <property type="term" value="P:positive regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1160.11:FF:000001">
        <property type="entry name" value="Paired amphipathic helix protein Sin3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1160.11:FF:000002">
        <property type="entry name" value="Paired amphipathic helix protein SIN3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1160.11:FF:000003">
        <property type="entry name" value="Paired amphipathic helix SIN3-like protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1160.11">
        <property type="entry name" value="Paired amphipathic helix"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013194">
        <property type="entry name" value="HDAC_interact_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003822">
        <property type="entry name" value="PAH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036600">
        <property type="entry name" value="PAH_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039774">
        <property type="entry name" value="Sin3-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031693">
        <property type="entry name" value="Sin3_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12346:SF0">
        <property type="entry name" value="SIN3A, ISOFORM G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12346">
        <property type="entry name" value="SIN3B-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02671">
        <property type="entry name" value="PAH"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08295">
        <property type="entry name" value="Sin3_corepress"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16879">
        <property type="entry name" value="Sin3a_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00761">
        <property type="entry name" value="HDAC_interact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47762">
        <property type="entry name" value="PAH2 domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51477">
        <property type="entry name" value="PAH"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6 7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0678">Repressor</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="4" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Histone deacetylase interacting" evidence="9">
        <location>
            <begin position="419"/>
            <end position="522"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="52"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="8">
        <location>
            <begin position="95"/>
            <end position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00810"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00761"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OBZ86626.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="1005" mass="117313" checksum="A3D0ABF81EE5EB66" modified="2016-11-30" version="1">MTLPKQQDTRSPIPPPILSYNHHLGITTLKSPQDRPSSRSLPPPPSVNTLTSLRSPYSPSSNSSPIVMKNVERNVRPALMSPTPSPSTTPFHPTELPPPPPPPPQVTADPSLTNQNTYRPLNVTDALSYLDLVKNRFSDRPDVYNQFLDIMKDFKSQAIDTPGVIKRVSSLFKGHSELISGFNTFLPAGYRIECPTGSHGIIVITPTETMTIENHPEKKKPPIEFNHAISYVNRIKNRFAYNPDIYKQFLEILQTYQKEQKSIGEVYAHVCYLFKDADDLVEEFKQFLPELMEPHGLKRHHQQSKTKKRPYVTKRAKLEKRDSEDLVDTQPVSSMEISLFDKIKQHIGNKPSYDEFLKLLNLYTQQIIDIHLLVTQAKRFIGQDKELFQAFQTVIGYDPQQSQTIERPAQSVPKPDLNKCPTIQASPSYRSVPRDWQTQPCSGRDQMCWEVLNDEYVSYPIWASEDSFVITSKRNLHEEALHRVEEERYDYDVHIEANQSAIALLRPIALQLEHMSDEEKEAMQLKPGLGGPTVSIYERMIKKVYDDDRGQEIIQMLYQKPAYVVPVLLNRLQLKDQEWRKAQREWNKIWREQEEMNFYKSLDYQGHSFKMNDKKALTTKAWLAEPHPITLAFENPAFFTSVSQLIYTFLDRQQSMSKEDREKLKEFIDSLTGYLFRSNPTKQKLDQLDLFATAAAFTAPQQEDMLYDKKIPFFCHTNYYCLVRLYHVLFERLYRLKSLSDQIKANPSLGKRCNTTAKELDLITTRFDDIDLSNGYYEAAIEIMDRFFKGEYDQNTFEENLRYVFGIDAYIVFTVDKVLQSLIKQIQTVWSDKKSIQLLTYYQEFKHPTDGVTMMSYHDKVIDLLGTHETIYQIDIDQETKKTTIYLLDQDKDVSEQRAYKDYLNSYIDWMNTTKGIDLSQLKPSFLSRTLQPNDYHFKYSRIRSQLRYKIQEKTYHMYYIVDSEDILHRKPLNVLQDNTSYKWNEWLTRKGNDTLSAQAKALFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NE25</accession>
    <name>A0A1C7NE25_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">Low affinity vacuolar monovalent cation/H(+) antiporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">A0J61_04596</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000228">
        <property type="protein sequence ID" value="OBZ87352.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NE25"/>
    <dbReference type="FunCoup" id="A0A1C7NE25">
        <property type="interactions" value="147"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NE25"/>
    <dbReference type="InParanoid" id="A0A1C7NE25"/>
    <dbReference type="OrthoDB" id="16982at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005774">
        <property type="term" value="C:vacuolar membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015369">
        <property type="term" value="F:calcium:proton antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006874">
        <property type="term" value="P:intracellular calcium ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1420.30:FF:000014">
        <property type="entry name" value="Cation/H+ exchanger protein 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1420.30">
        <property type="entry name" value="NCX, central ion-binding region"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004713">
        <property type="entry name" value="CaH_exchang"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004837">
        <property type="entry name" value="NaCa_Exmemb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044880">
        <property type="entry name" value="NCX_ion-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005185">
        <property type="entry name" value="YccF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31503">
        <property type="entry name" value="VACUOLAR CALCIUM ION TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31503:SF10">
        <property type="entry name" value="VNX1 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01699">
        <property type="entry name" value="Na_Ca_ex"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03733">
        <property type="entry name" value="YccF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0406">Ion transport</keyword>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="149"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="277"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="350"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="390"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="419"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="453"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="487"/>
            <end position="507"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="556"/>
            <end position="576"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="679"/>
            <end position="697"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="717"/>
            <end position="737"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="749"/>
            <end position="771"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="783"/>
            <end position="804"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="811"/>
            <end position="831"/>
        </location>
    </feature>
    <feature type="domain" description="Inner membrane component" evidence="12">
        <location>
            <begin position="147"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="domain" description="Sodium/calcium exchanger membrane region" evidence="11">
        <location>
            <begin position="390"/>
            <end position="501"/>
        </location>
    </feature>
    <feature type="domain" description="Sodium/calcium exchanger membrane region" evidence="11">
        <location>
            <begin position="679"/>
            <end position="829"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="9">
        <location>
            <begin position="10"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="37"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF01699"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF03733"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="OBZ87352.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="15">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="848" mass="95035" checksum="4939B6C96D31BABE" modified="2016-11-30" version="1">MDSPSADRPKLHKTRSTPSARTRRSNRGAPFKYGAISEQPENNSSSSNEDDDSAQSIARRKSTAFEQMGEAETEDTSQMNHYLSTGNLLDYELTLKDKQDAMNKQHPFGLPLWKPALYKKSRSVVRKANSSLHSSPSSSSELFLNPGNILWSVLFGWWLAFVVFCVSLPLSLFKNHAYGMVLRELSLYLLWPFGRYVERLVEITPEVMSDLERERSTGQASILIEDEDEDEHVETEETHRRHQQQHKRKHYNLIRAVVDTIRLGPVGWLYYSLFYVIIAPLLLLVSTICWMCVVTVPMAKLNYILVRHLRRHPQKLRFRSKPSVLMGSNHQPTIILLCTYQAFGWQYYKYTFNGINIMFINLIPLVFFVIFDDYYLKDYMPDSLIASPQFIFALSLASVIPLSYFIGMGVSSVSAQSSMGLGAVINATFGSIIEIILYAAALMAGKSSLVEGSLIGSILAGVLLMPGFSMISGAVKRKEQRFNAKSAGVTSTMLIMAIIGALSPALFYQFFGSFELHCTGCPEGADTNGSLACSHCYYDQMDLFEDPVYQNSVKPFMLICAAILPSAYVIGLLFSLHTHADMVWKSQSTSKPNENVTQQVYPVQIIQPAQQEEPNEQTPLQAPANAQASVIQVIEANHLQASTVAQPLTFVHAKEPEEEEEEEAAAGHDSPNWGKTMSYSVLFGCTLLYSIIAEILVQTVDLVMEDVAIDEKFLGLTLFALVPNITEFMNAISFALYGNIVLSMEIGSAYALQVCLLQIPAMVGFSLWFNWGKEELKKFTFNLMFPRWDVISVIFSVFLLTYTYQEGKSNYFKGSILILSYVVLVAGFYYIPSSSNASQAFFAINSKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NES9</accession>
    <name>A0A1C7NES9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Derlin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">Derl2</name>
        <name evidence="9" type="ORF">A0J61_04338</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Endoplasmic reticulum membrane</location>
            <topology evidence="1 7">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the derlin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000210">
        <property type="protein sequence ID" value="OBZ87615.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NES9"/>
    <dbReference type="FunCoup" id="A0A1C7NES9">
        <property type="interactions" value="238"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NES9"/>
    <dbReference type="InParanoid" id="A0A1C7NES9"/>
    <dbReference type="OrthoDB" id="1716531at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006950">
        <property type="term" value="P:response to stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007599">
        <property type="entry name" value="DER1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035952">
        <property type="entry name" value="Rhomboid-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11009">
        <property type="entry name" value="DER1-LIKE PROTEIN, DERLIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04511">
        <property type="entry name" value="DER1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144091">
        <property type="entry name" value="Rhomboid-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="25"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="65"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="112"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="197"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="228"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="242"/>
            <end position="256"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU363059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OBZ87615.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="256" mass="29603" checksum="CF226020188F760C" modified="2016-11-30" version="1">MGFIHPLQLWLNYESIARDFQWWRLITNFFYFGPLSIDFCFHIFFLARYSRMMEEGFYRNKPADYVWLMLFSASVLLVISVVVPFASLPFMGSALSFTMVYIWARRNPYVRLNFLGLVVFTAPYLPWVLLMFSLCLGGQIPTGDILGVLVGHIYYFFEDVWPRDPMSGGKKWLATPRLVRWLIEGNRPRDDSIDIVEPEEEQQQQEHVAQTTEETVEIAEDQASSSEKANEKEHVSPENSKEPSSLETPSSSSLST</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NEV4</accession>
    <name>A0A1C7NEV4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Ovarian-specific serine/threonine-protein kinase Lok</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">lok</name>
        <name evidence="7" type="ORF">A0J61_04672</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. CHEK2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000233">
        <property type="protein sequence ID" value="OBZ87279.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NEV4"/>
    <dbReference type="STRING" id="101091.A0A1C7NEV4"/>
    <dbReference type="InParanoid" id="A0A1C7NEV4"/>
    <dbReference type="OrthoDB" id="407410at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004672">
        <property type="term" value="F:protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00060">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000571">
        <property type="entry name" value="Maternal embryonic leucine zipper kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.200.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000253">
        <property type="entry name" value="FHA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008984">
        <property type="entry name" value="SMAD_FHA_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24347">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00498">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00240">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49879">
        <property type="entry name" value="SMAD/FHA domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50006">
        <property type="entry name" value="FHA_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0418">Kinase</keyword>
    <keyword evidence="2 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="FHA" evidence="5">
        <location>
            <begin position="112"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="6">
        <location>
            <begin position="217"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="246"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005575"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OBZ87279.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="508" mass="58329" checksum="7E91781F696EA94B" modified="2016-11-30" version="1">MKFSCKLSRSTSTPDLKGSQKICERARENADRLKKRQSVGIAYSPLVGFSPEAKRRLAQPAKSSTMIKRRNDGYCDLIETKNAWGYLVQGNGHVFVFDRQLSNRKHNEPAGYVIGSGKDCDIIIHHKAAEERHAFIFYETRFQDNKYSMPVYICNQSANGIWINGKKMVNQIQKIKTNDHIFFLDPNTYMTKENICYVFVEPKQPLSTVKSIDTLYQSTHESLGEGNYGKVYLAKCKETGNRVAVKVVPRRSFKDLPQWQIALLREVSVCMLFPDHPCIVKISRMFVKNEDMYIIMEYGPHGDLFEMIVDGDYHYKEHEVRILFDQIAHAVACLHENNIVHRDIKLENVIVTDKANLRVKLCDFGFSTIARPGRDLLTGCGTSFYAAPEIKRKKPYSKSVDIWSLGMLLYVSLTSSHPYALPGKEEDYVPEHTGNSAKYRTDHPRWKSLSKDAKDLVNKMLQVDPKKRVDIQQVLDHPWLQNINNLESIKAGVKRNPLLVDYLESKKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NEZ4</accession>
    <name>A0A1C7NEZ4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Ankyrin-2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">ANK2</name>
        <name evidence="6" type="ORF">A0J61_06056</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000348">
        <property type="protein sequence ID" value="OBZ85894.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NEZ4"/>
    <dbReference type="InParanoid" id="A0A1C7NEZ4"/>
    <dbReference type="OrthoDB" id="539213at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051165">
        <property type="entry name" value="Multifunctional_ANK_Repeat"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24123">
        <property type="entry name" value="ANKYRIN REPEAT-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24123:SF33">
        <property type="entry name" value="PROTEIN HOS4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00023">
        <property type="entry name" value="Ank"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13637">
        <property type="entry name" value="Ank_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13857">
        <property type="entry name" value="Ank_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="65"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="385"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="519"/>
            <end position="553"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1087"/>
            <end position="1111"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1225"/>
            <end position="1244"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1346"/>
            <end position="1393"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="787"/>
            <end position="814"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="954"/>
            <end position="1045"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="1151"/>
            <end position="1185"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="1099"/>
            <end position="1108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="1231"/>
            <end position="1244"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="1350"/>
            <end position="1360"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="1368"/>
            <end position="1393"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OBZ85894.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="1462" mass="165664" checksum="3F302E111B816A48" modified="2016-11-30" version="1">MDFLQAIVNNDVEKVRGMIQKGIDVNGTYNWNSKDTFSPLIPTNFIHQSELLSSIQTDQEYLCRPLNLAVFAGHANMVRLLLSAGADINSKDEMADRTTITHDGSLKRTAIVCAIFGFDLDASNINTSNLHLIGATNPSHFDIMKNILLCHPNLYYCTLDSPQYEIKGITPLCLASYLGKTALIQLLLEDDRVNVDGTDSKKATALMYAGKYNVPLQKYTLETIHIGFYTARDGNLPIVKMLLDYHASPDKTDSHGWSALQYAEKNPEVMRLCEQNLRLKRAELTDAVYQCNISYPVNYARLAHLLTTIPNYPSSLSHLQFDSLRDIDHLDPSAAGLVQIVQAAFLQAIRIHDHLSLQTLLMQSPPLNRSQRGGPLLVNHHDAKNGLTAFHYAMRTKPLPSLDTITLLFQAGADMNAQTYYGRTALHHLARFGLDKDGVTWGIQKGFNPKETRTGQMMTMRRLGSTESNSMPSHQPELSQTTTTVIETMMGVTNVPEHLAMCVSLLIQFGALVNIADPIGNTPLHFAAEFGGVSEVLEVLILEGNADLHLRNKKGLTPLDVCKSEELKRKMLQFEADRRNCQNTRSILSSLNGTIRPFDSASEYNRSSLVFTSNHTMTHSNALLFLTDSKMHMSHIKQLLTHTIQRKREEASHEDYSDFDVILKAFFFYQTNFADSVGARLTIITASISSSGGGGQADEDKRELFSQKLKHITSKLKHELRDAHEMFAVTDQLVEKAMIDFREELEQVEQVHQTDWELSDVQHDKIEKLFDVFERIDHRFCQLELAQDDLIDQIERLRKAAARKQHQFRLAEEQTALPDIGNCLSHVLQALLILSSIPTDRLPYLKDNRHSLYQDMAHVVDQVLKELGKKEDVYFRNARALVESRWLTVKDVLTKEYSPEEKEVRLVQHDMSRSSSSQSTINAWKKNKLMSFSAQPKPSLNELELSFDILQSNLYEIQKDVEEINNHLERLTETKKKMYEVCLDLERQLDTKEESADQKVQQELDQVLAFTQKVFDKQASLDQEKKQLLLEHDAIEKRLDTTRESLRKVRPPALLQSLLERLDTDEVPSVQIEKDWKEDSNLVSEIVDHDSPAEDTDDSCASSTTSQSPELTALQTKQLSIQCESELSTLCYLARLDASLYCVKVLASHMISKSRQQLVQVQTTLRQASDELDEIRNHLTQLYDDAAEVARQVYALKTELERIVRHRKEEVIKVWEVADEVSKSFNPHQAQRHESHDSFLSEQKEYSEEQERHQWIVRELEQLYHVHESLKCSAANLKHEQSVIGQSLKTLASQSVEPQVDTLVGQDNRSLLSVSDQLAELMDSVREHEVGLRSVSFWSTPQAMIKPESSKTPAISASRTTEAEPSSRHSSNTLSMASHRLSASTHNSRRSSYYTKSMVDNKNISLRLSAAISIKGEKKRMSMISATSLSSLSSYQQEKMMAKAAHLSSVLIKAQQQQTLKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NF34</accession>
    <name>A0A1C7NF34_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">60S ribosomal protein L14</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">rpl14_0</name>
        <name evidence="6" type="ORF">A0J61_04226</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the eukaryotic ribosomal protein eL14 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000202">
        <property type="protein sequence ID" value="OBZ87721.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NF34"/>
    <dbReference type="FunCoup" id="A0A1C7NF34">
        <property type="interactions" value="578"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NF34"/>
    <dbReference type="InParanoid" id="A0A1C7NF34"/>
    <dbReference type="OrthoDB" id="1875589at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022625">
        <property type="term" value="C:cytosolic large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042273">
        <property type="term" value="P:ribosomal large subunit biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd23702">
        <property type="entry name" value="eL14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.2270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005824">
        <property type="entry name" value="KOW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014722">
        <property type="entry name" value="Rib_uL2_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039660">
        <property type="entry name" value="Ribosomal_eL14"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002784">
        <property type="entry name" value="Ribosomal_eL14_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008991">
        <property type="entry name" value="Translation_prot_SH3-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11127">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11127:SF2">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN EL14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00467">
        <property type="entry name" value="KOW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01929">
        <property type="entry name" value="Ribosomal_L14e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50104">
        <property type="entry name" value="Translation proteins SH3-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 6" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="KOW" evidence="4">
        <location>
            <begin position="18"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="domain" description="Large ribosomal subunit protein eL14" evidence="5">
        <location>
            <begin position="56"/>
            <end position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006592"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00467"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OBZ87721.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="145" mass="15942" checksum="A9B4CAD393696E49" modified="2016-11-30" version="1">MFSPINAQQGSFKRQVEVGRVVLINHGADAGKLAVIVDIIDHNRALIDGPTTGVVRQAFAYKRLVLTPLVLKNLPRNIGKAALVKALEKNETVAAWNKTAWAKKIEQRKVRAGLSDFDRFKLAKLKNQRRFAVGSTVAAAKKQTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NFJ9</accession>
    <name>A0A1C7NFJ9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Solute carrier family 25 member 46</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">SLC25A46</name>
        <name evidence="11" type="ORF">A0J61_04119</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion outer membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000194">
        <property type="protein sequence ID" value="OBZ87828.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NFJ9"/>
    <dbReference type="InParanoid" id="A0A1C7NFJ9"/>
    <dbReference type="OrthoDB" id="2403262at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005741">
        <property type="term" value="C:mitochondrial outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090149">
        <property type="term" value="P:mitochondrial membrane fission"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039158">
        <property type="entry name" value="SLC25A46"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21252:SF2">
        <property type="entry name" value="MITOCHONDRIAL OUTER MEMBRANE PROTEIN SLC25A46"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21252">
        <property type="entry name" value="TB1 PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5" id="KW-1000">Mitochondrion outer membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 9 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2 10" id="KW-0813">Transport</keyword>
    <feature type="repeat" description="Solcar" evidence="9">
        <location>
            <begin position="67"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="9">
        <location>
            <begin position="263"/>
            <end position="353"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004374"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="OBZ87828.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="380" mass="43261" checksum="178EA335EE9DEDA1" modified="2016-11-30" version="1">MTLTAYLGFLSLGSTIQTRRSVECQQEQEQEVKALQAMAEAISQAEIDTVSTVSVHHAPSERKIEIRENIMGVTLAIGTMVANYSFCFPIVAARHRLQALPHPHRYDTPLYGAQMILRTYRQGGLRRLYPGFGLGLMGQAVSASYESCVQQIITAFCTHPILSPILAKSLGFLIQIPLYPLYRNALIMRVQYDTATTQQVINSWHDFVRLYRRDLVGFQNHIACFIPSCLLNALTEKLLIAIYRRIFQSFQSEKKKKEATVLHTFYPEIACGVISSIVTRALSYPIDTVLFKLMIQGSGVLRTETDYHGFFDCVQRTWQEGIKGFYPGWGIGLLEIGMGYMILEASWWAYRLVQWKLQTLGSSDTRTVRKAKKLRDRFLH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NFX4</accession>
    <name>A0A1C7NFX4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Gamma tubulin complex component C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">A0J61_05677</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TUBGCP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000314">
        <property type="protein sequence ID" value="OBZ86264.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NFX4"/>
    <dbReference type="STRING" id="101091.A0A1C7NFX4"/>
    <dbReference type="InParanoid" id="A0A1C7NFX4"/>
    <dbReference type="OrthoDB" id="775571at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000930">
        <property type="term" value="C:gamma-tubulin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005816">
        <property type="term" value="C:spindle pole body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043015">
        <property type="term" value="F:gamma-tubulin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007020">
        <property type="term" value="P:microtubule nucleation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1900">
        <property type="entry name" value="Gamma-tubulin complex, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040457">
        <property type="entry name" value="GCP_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042241">
        <property type="entry name" value="GCP_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04130">
        <property type="entry name" value="GCP_C_terminal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="4" id="KW-0493">Microtubule</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Gamma tubulin complex component C-terminal" evidence="6">
        <location>
            <begin position="7"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010337"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF04130"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OBZ86264.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="145" mass="17133" checksum="6748AD841F0933DF" modified="2016-11-30" version="1" fragment="single">SAIMEPQAFKEYHEHMLDCILFQCFLKQSQSRIMQVMTPILQDIVLFGIVLDDYGANEAMIEQEEKLEIRCRKLFDQFQRNRAMFVHVLKTLEQKGTGRLSNILKSTRKSVFNELYMKYEAKHGMDVFVKDLLVRLSLNESHEQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NFX8</accession>
    <name>A0A1C7NFX8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">ATPase inhibitor, mitochondrial</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">A0J61_03948</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Inhibits the enzyme activity of ATPase.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 4">Belongs to the ATPase inhibitor family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000182">
        <property type="protein sequence ID" value="OBZ88002.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NFX8"/>
    <dbReference type="STRING" id="101091.A0A1C7NFX8"/>
    <dbReference type="InParanoid" id="A0A1C7NFX8"/>
    <dbReference type="OrthoDB" id="5532350at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042030">
        <property type="term" value="F:ATPase inhibitor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.500">
        <property type="entry name" value="Single helix bin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007648">
        <property type="entry name" value="ATPase_inhibitor_mt"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04568">
        <property type="entry name" value="IATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64602">
        <property type="entry name" value="F1 ATPase inhibitor, IF1, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="51"/>
            <end position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010901"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU368087"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OBZ88002.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="88" mass="10097" checksum="D0210DFB67B48870" modified="2016-11-30" version="1">MFIKSTQRVFTRLIVRVPKRTVMYQTGSEGATAQSGSFGQKEKAIENQWARAHDAEKLKILREALQKHEKETATLKKNIEDLAKKHES</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NGD8</accession>
    <name>A0A1C7NGD8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="8">U3 small nucleolar RNA-associated protein 6</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">Utp6</name>
        <name evidence="8" type="ORF">A0J61_04133</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the UTP6 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000195">
        <property type="protein sequence ID" value="OBZ87819.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NGD8"/>
    <dbReference type="STRING" id="101091.A0A1C7NGD8"/>
    <dbReference type="InParanoid" id="A0A1C7NGD8"/>
    <dbReference type="OrthoDB" id="28112at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034388">
        <property type="term" value="C:Pwp2p-containing subcomplex of 90S preribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032040">
        <property type="term" value="C:small-subunit processome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030515">
        <property type="term" value="F:snoRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000462">
        <property type="term" value="P:maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003107">
        <property type="entry name" value="HAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013949">
        <property type="entry name" value="Utp6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056907">
        <property type="entry name" value="UTP6_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055347">
        <property type="entry name" value="UTP6_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23271">
        <property type="entry name" value="HEPATOCELLULAR CARCINOMA-ASSOCIATED ANTIGEN 66"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23271:SF1">
        <property type="entry name" value="U3 SMALL NUCLEOLAR RNA-ASSOCIATED PROTEIN 6 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08640">
        <property type="entry name" value="U3_assoc_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24892">
        <property type="entry name" value="UTP6_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00386">
        <property type="entry name" value="HAT"/>
        <property type="match status" value="9"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0698">rRNA processing</keyword>
    <feature type="domain" description="U3 small nucleolar RNA-associated protein 6 N-terminal" evidence="6">
        <location>
            <begin position="9"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="domain" description="U3 small nucleolar RNA-associated protein 6 homolog C-terminal" evidence="7">
        <location>
            <begin position="349"/>
            <end position="623"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010734"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF08640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF24892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OBZ87819.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="639" mass="74973" checksum="C47138D7B9E087A6" modified="2016-11-30" version="1">MAESVQYYLERMIPELEGLEKKNIFSPVEIKSIIKKRTNFEYALHRRIKQKIDFLRAIEYEINLEELRKKRVSRMGITDSLKGNDLQYSGTRRIYNLFRRATIKFKNDLSLWLQYIDYAKRNKSNNVLSSVFVQAIQYHPHNASLWIMAATWENEENANIAAARVLMQRALRLMPENQQLWHEYFRLELLYIEKIKLRRRLLGIDQQKNAEDIEPINNENDDNTLQLPALTGEDVAQWQQDEQDKKKKKMTEQEMAALEEANNPILQGLLAKIVYDNAIQAIPSDIEFRQRFIEIYREFTDTETHVDYVYQTIQNDLKYPKARTVLAKRHLTPNLTVSDPQFVTALRACVADFEEAVNSLNESEMWQDYAEFILSWHTVVSEENLKLYLTKLALKIFKNCHKQHKMNGPLYQSWTELLMATDQGEKAIDVAERGLNAFPQQAGLWIDWIQLIEDKQDGYKKALAVNPESLDLWRSFLKWIDSSELNGEEKHDAFFDACTKATLLLPSVTSESAERNEIKQIVQSSYVTWAAETEGIESARAVYRKLIKTFYPTYALLMKCIELENQYGSPDQQGQNSVEFLYDKVTNMESHKEETYLAYLAYLYSQKKFQKANQVYNRACKELPNREAFDIQIQKLRSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NH31</accession>
    <name>A0A1C7NH31_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Pre-mRNA-splicing factor 18</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">prpf18</name>
        <name evidence="10" type="ORF">A0J61_03521</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the PRP18 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000153">
        <property type="protein sequence ID" value="OBZ88422.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NH31"/>
    <dbReference type="FunCoup" id="A0A1C7NH31">
        <property type="interactions" value="513"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NH31"/>
    <dbReference type="InParanoid" id="A0A1C7NH31"/>
    <dbReference type="OrthoDB" id="10261918at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071021">
        <property type="term" value="C:U2-type post-spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046540">
        <property type="term" value="C:U4/U6 x U5 tri-snRNP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005682">
        <property type="term" value="C:U5 snRNP"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000350">
        <property type="term" value="P:generation of catalytic spliceosome for second transesterification step"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.940.10">
        <property type="entry name" value="Functional domain of the splicing factor Prp18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.280.110">
        <property type="entry name" value="Pre-mRNA processing factor 4 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004098">
        <property type="entry name" value="Prp18"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014906">
        <property type="entry name" value="PRP4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036285">
        <property type="entry name" value="PRP4-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039979">
        <property type="entry name" value="PRPF18"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13007">
        <property type="entry name" value="PRE-MRNA SPLICING FACTOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13007:SF19">
        <property type="entry name" value="PRE-MRNA-SPLICING FACTOR 18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02840">
        <property type="entry name" value="Prp18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08799">
        <property type="entry name" value="PRP4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00500">
        <property type="entry name" value="SFM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47938">
        <property type="entry name" value="Functional domain of the splicing factor Prp18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF158230">
        <property type="entry name" value="PRP4-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="6" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0747">Spliceosome</keyword>
    <feature type="domain" description="Pre-mRNA processing factor 4 (PRP4)-like" evidence="9">
        <location>
            <begin position="72"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="29"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="29"/>
            <end position="44"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00018242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00500"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OBZ88422.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="325" mass="38137" checksum="90B39901EC1CA602" modified="2016-11-30" version="1">MSFLDSIIQEEVSKKRKILDTVEKGADKKLKYKKARQEQEEIKRKQLNKQTTQPEKKTEETDNEETIETFNISREECIRRLRAMGQPIRLFAETDKQCKVRLRALELMNEESGNQGRNEFMKTLEEMEANMRLDELKQKSGVPDDKKKPRKSTMVVEPIQLDLIQKDIDKLYYQIYAYFTHTLEEWEEYMLQRPEEEKRSGPGKRAAVLQKQAAEYIKPLLRHLKKKTLEPDVLNRVAEIAQRMQARLYRDAQDAYLQLSIGNAPWPIGVTMVGIHERSAREKISSSQVAHVLNDETSRKWIQSVKRLMTFAQTKYPPHTLSQIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NHK1</accession>
    <name>A0A1C7NHK1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Putative nitronate monooxygenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">A0J61_05119</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the nitronate monooxygenase family. NMO class I subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000268">
        <property type="protein sequence ID" value="OBZ86834.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NHK1"/>
    <dbReference type="STRING" id="101091.A0A1C7NHK1"/>
    <dbReference type="InParanoid" id="A0A1C7NHK1"/>
    <dbReference type="OrthoDB" id="2349068at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018580">
        <property type="term" value="F:nitronate monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04730">
        <property type="entry name" value="NPD_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004136">
        <property type="entry name" value="NMO"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42747">
        <property type="entry name" value="NITRONATE MONOOXYGENASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42747:SF3">
        <property type="entry name" value="NITRONATE MONOOXYGENASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03060">
        <property type="entry name" value="NMO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51412">
        <property type="entry name" value="Inosine monophosphate dehydrogenase (IMPDH)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4" id="KW-0288">FMN</keyword>
    <keyword evidence="6 7" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OBZ86834.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="373" mass="40364" checksum="0F425BD66D8DEB88" modified="2016-11-30" version="1">MSHILQNSFTRALKLKYPIVQAPCAGHTGVELITAVSNAGGLGSLGAGMMPVDLLRKTIRDIHNKTSNPFAVNLFCRPAHIVSEADLQKHCPGVDDTLDAIRSELNIPIPAEYKLRSPPLEDQLAVILEERVPVVSFTFGVLPDHFRDQLWAAGTYLIGTATTLQEALMLAGLDPSSPTRKADAIVAQGLEAGGHRGSFLADGQQLDRTQLVKSIKQHVSLPILAAGGISTGTDVSHVLQKEEADAAVIGTLFMLATESTTPKAHREHMIHAEKKGLEPTRITTAITGKHVRSYPNELMKRIEKAAEESDVQVPEYSIHSSKTKDIAEYATKHHLADYMLLLAGANASEAVKYTKQGTLSAKQIIDKIVSEIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NI26</accession>
    <name>A0A1C7NI26_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Biofilm and cell wall regulator 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">BCR1_1</name>
        <name evidence="12" type="ORF">A0J61_03780</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000170">
        <property type="protein sequence ID" value="OBZ88166.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NI26"/>
    <dbReference type="STRING" id="101091.A0A1C7NI26"/>
    <dbReference type="InParanoid" id="A0A1C7NI26"/>
    <dbReference type="OrthoDB" id="10018191at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000433">
        <property type="term" value="P:carbon catabolite repression of transcription from RNA polymerase II promoter by glucose"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:002343">
        <property type="entry name" value="Zinc finger protein 33A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051007">
        <property type="entry name" value="creA/MIG_C2H2-ZnF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47428">
        <property type="entry name" value="REGULATORY PROTEIN MIG1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47428:SF2">
        <property type="entry name" value="ZINC FINGER PROTEIN RSV1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="7" id="KW-0804">Transcription</keyword>
    <keyword evidence="6" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 9" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="11">
        <location>
            <begin position="14"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="11">
        <location>
            <begin position="45"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="82"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="10">
        <location>
            <begin position="82"/>
            <end position="97"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="OBZ88166.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="160" mass="18446" checksum="8A6E28FD67C0BF09" modified="2016-11-30" version="1">MHTKRTKNTKPKLFQCTGYGDCNMVFTRSEHLARHARKHTGEKPFLCIVPGCSKAFSRFDNMMQHTQTHRNLQQELVIHQAKKSIRRTRSSNSKHRPLPALCSSSSSSEEEEDDLSPPPHRRLSVADLCNPPQLSLDHLTKDEYEAIEALDRFHNSFQCF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-06-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NI74</accession>
    <name>A0A1C7NI74_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_03106</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000128">
        <property type="protein sequence ID" value="OBZ88843.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NI74"/>
    <dbReference type="InParanoid" id="A0A1C7NI74"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ88843.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="80" mass="9585" checksum="A1F071E22A48926F" modified="2016-11-30" version="1">MNTARNLALISGSQLQEYLFLFDPMLDSEMKELKKYRCPTNQEHFARNSKKDTVTTELLKQVKFFDEYQGQYAKHNRDKY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NID1</accession>
    <name>A0A1C7NID1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">FAS1 domain-containing protein fsc1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">fsc1_1</name>
        <name evidence="4" type="ORF">A0J61_04848</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000247">
        <property type="protein sequence ID" value="OBZ87104.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NID1"/>
    <dbReference type="FunCoup" id="A0A1C7NID1">
        <property type="interactions" value="32"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NID1"/>
    <dbReference type="InParanoid" id="A0A1C7NID1"/>
    <dbReference type="OrthoDB" id="14252at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.180.10">
        <property type="entry name" value="FAS1 domain"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050904">
        <property type="entry name" value="Adhesion/Biosynth-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036378">
        <property type="entry name" value="FAS1_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000782">
        <property type="entry name" value="FAS1_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10900:SF77">
        <property type="entry name" value="FI19380P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10900">
        <property type="entry name" value="PERIOSTIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02469">
        <property type="entry name" value="Fasciclin"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SMART" id="SM00554">
        <property type="entry name" value="FAS1"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82153">
        <property type="entry name" value="FAS1 domain"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50213">
        <property type="entry name" value="FAS1"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008889713" evidence="2">
        <location>
            <begin position="21"/>
            <end position="813"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="759"/>
            <end position="782"/>
        </location>
    </feature>
    <feature type="domain" description="FAS1" evidence="3">
        <location>
            <begin position="21"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="domain" description="FAS1" evidence="3">
        <location>
            <begin position="295"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="domain" description="FAS1" evidence="3">
        <location>
            <begin position="443"/>
            <end position="594"/>
        </location>
    </feature>
    <feature type="domain" description="FAS1" evidence="3">
        <location>
            <begin position="599"/>
            <end position="747"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50213"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OBZ87104.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="813" mass="92131" checksum="CA2DEF1BAC17CDBF" modified="2016-11-30" version="1">MNTYYLTLIFAFTFLSGIHAYKTIVDVLSEDARFSTLIRHLQLTHLIPKINNLESGTFFAPDNSAFEKYKGPPITADILMYHLLPQQFSTKDFGDGQILESSYVRPGLLGDDKTGQKLKVTTTFDMFYHINEARIKDKDIFVNRNTTLNVVDRVLEPPRMLYEMAPIYDSKLFDLWKKAGLDNNLRQRHPFTIFVSAKYLLDRFSHVEQSYLTSHYGQDDLKHALKYLMVPQAIFLNQHKQDETIYMTESGETVKINVNRYKQATVNGIKVEEQDILAADGVIHILNDLPYADSIVFDTRKYLFGLNATKFVSLIDSYGLGRFLNKGTNNVTILAPTNEVIDEDSIPNNQKTQWLSYHLVQGAYSPSELTDRMLVKTEFNSSQLYNDSQRLFVSIGKSKEDTMENMNAFIKSIRFGDYSKVVGVDMAIDGNVIYRISDPLALPMDIFSRLVVDLELSSFIATLYVSGVVDRIKRSKAITLFAPTNQAFKNLGLVSRYLVHPTGRSDLQRVLLFHAATSPLYHHDLRGDVLRVTTLAENESLIINGQNADGSIWIGTETKSEKDAEGNTVDEHGVIQQSDMLVSNGVVHKIDHIQIPNHVNITHRNLLRGINANIMLNILRRTNLIDQLDMTDNFLLAPTDKAFEHIDLEPLWNDTAKLERIARMHIVPKVSVDNSRKRWFIYPFLGDQEYSTLLSNRDKIVVREMGYGLTVIRVKGEPYSPYVRVLDIGHVSTGDRSGGVVEIDAVLFPVKRGAFGLPWIWSLVTLTLLSALGALVFLIGGCMGYKMWKRKRAGYQTIADDSTLPDQSEQANA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-06-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NIT0</accession>
    <name>A0A1C7NIT0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_02928</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000118">
        <property type="protein sequence ID" value="OBZ89011.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NIT0"/>
    <dbReference type="InParanoid" id="A0A1C7NIT0"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ89011.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="99" mass="11376" checksum="EACCDBB96CFFE01E" modified="2016-11-30" version="1">MIQLAHQKKPMMNMMLLLPQKDDLDIQVSSLVTFAATSKTPLGVKNSNSTFNLNEWKLNDISTNDAFIKKIRQYIDHSLDDLMKRAGYCSFQEDLLKLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NJC3</accession>
    <name>A0A1C7NJC3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Armadillo repeat-containing protein 7</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">ARMC7</name>
        <name evidence="1" type="ORF">A0J61_03035</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000124">
        <property type="protein sequence ID" value="OBZ88909.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NJC3"/>
    <dbReference type="STRING" id="101091.A0A1C7NJC3"/>
    <dbReference type="InParanoid" id="A0A1C7NJC3"/>
    <dbReference type="OrthoDB" id="201709at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042462">
        <property type="entry name" value="ARMC7"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46263">
        <property type="entry name" value="ARMADILLO REPEAT-CONTAINING PROTEIN 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46263:SF1">
        <property type="entry name" value="ARMADILLO REPEAT-CONTAINING PROTEIN 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ88909.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="148" mass="17189" checksum="F9C2A4E1B8066645" modified="2016-11-30" version="1">MFQSKKYIEQRHGKESANREDHLKLLVQEYQVTQSQEAKQQILANLANFAYDPINYNTLWDLQVIQLFLDALEEHDGLLQEFGIGGIANICLAFIQTQHGWLPKGHLYLKHTDERNDRIDATSDTRQLYDLIDIRTKGPSETDSDWSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NJF1</accession>
    <name>A0A1C7NJF1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Protein prune</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">PRUNE</name>
        <name evidence="2" type="ORF">A0J61_02670</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000103">
        <property type="protein sequence ID" value="OBZ89282.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NJF1"/>
    <dbReference type="FunCoup" id="A0A1C7NJF1">
        <property type="interactions" value="271"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NJF1"/>
    <dbReference type="InParanoid" id="A0A1C7NJF1"/>
    <dbReference type="OrthoDB" id="374045at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004309">
        <property type="term" value="F:exopolyphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.310.20">
        <property type="entry name" value="DHHA2 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1640.10">
        <property type="entry name" value="inorganic pyrophosphatase (n-terminal core)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038763">
        <property type="entry name" value="DHH_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004097">
        <property type="entry name" value="DHHA2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038222">
        <property type="entry name" value="DHHA2_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12112">
        <property type="entry name" value="BNIP - RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12112:SF39">
        <property type="entry name" value="EG:152A3.5 PROTEIN (FBGN0003116_PN PROTEIN)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02833">
        <property type="entry name" value="DHHA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01131">
        <property type="entry name" value="DHHA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64182">
        <property type="entry name" value="DHH phosphoesterases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DHHA2" evidence="1">
        <location>
            <begin position="215"/>
            <end position="364"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM01131"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ89282.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="368" mass="42585" checksum="EB32708C08E46FB4" modified="2016-11-30" version="1">MLTFSDFLKTVHQKKDHNDIQKVIVTGNDSAGILLIAHDKQLIHQDDSETLYIPFVKVPRADLALRPELKYVFEQISLDEQLLVCLDDIDLDKLAHESTKLVLVDHNHLTSPLDTPLWHDRVVGVLDHHVDEKMYLNAPLRVVEMVGSCVTLVLNQFPQDHWIIHRSLVQLALAPLLIDTVQLKWDLGRTTQKDMDLFELIQQHYSNTINFDDYFKAIERVKARVDGMPSYDILRRDYKEFHVKGHRIGTSAVTWYFDAWADRDGSSKSIEEAAMKFVQERGLAMEIVFTAFDHDKEGTGDYRRQLAVMCLDTKMEAVKEALVQTEAVQLKPIDHLQTNRLTFYDQGNIKMSRKQVWPLVRELIESKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NJQ3</accession>
    <name>A0A1C7NJQ3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DUF3730 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_02539</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000097">
        <property type="protein sequence ID" value="OBZ89402.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NJQ3"/>
    <dbReference type="InParanoid" id="A0A1C7NJQ3"/>
    <dbReference type="OrthoDB" id="6125419at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ89402.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1725" mass="194319" checksum="40102B4F542B1F94" modified="2016-11-30" version="1">MFKSTMITMSEEMIQHRLIQVQQATQRIQQADPWTFLLDSTVPAIAVSHSCEKIISQSNDDNFLQTLQSLQHLVLTCKDSLKTPILLSTITRLLLKNTRIEFYHHAKKAGVNQHHPFAVLLRQRPDMYFDLLEEFDIIFLQEPNQAWQKLKGFIYAVYLTEHQAEASHLLIRLQHHLVSHSSDEFRNQIYSNMVQLILNYPLQQESHRLLSLVDFLIYSHQPTQVVPELAYAFVDRLLAAVLNDSPVMPFLVRLERIMTLYPDALDPDLLWACLSFLLLKAQTVDQQQLLLQLIRSLCSAKEINAPVLRIAYLPLYQLLSELNDKEPSEQLKQLKQHTLHLISFLDQNKEKAWPDTNQLQEIAHSHTLYGPLSHIMIYMENIYSRLYPIYPIDDQKSSPVTFTLSLLFSIPFVFHEDRDIQCQVYSNIASLSEHYKFPVFLFLLRMLQSTEDPCLITHIFRDVLLKLADTNDPVMSSKILQVLLSAIPSNESSVVASLAVKALGQLYQRQPRVWQELKRVFSDWVLRRKSGSVRRKVDLTQTGPIKMELAILTTMRDVVAFRPRECAPDILPMAFSLLQSCPNLSMASLSILMHIINLSVEANLAEPRSIWQVTVVYLAMFAAEQGTPKSNLLIKQLCRFYAMAGARDDPSEYYLQFKQTLLTDYLLPLTECGDTKAVSYALEALACFPSKDITIILPEKASDYIQQLVTKSDQPNPSQHVLLTTLVSDELDNMRRGLFKQDANIKPTVASQAHEESMTNELGQVIAERELELDAIFKTQWEDARVAPGLRSGYALAMLNTMDASQNQPSIDMFKTHWYRFMVTSFTDVSLTDHLLIRISSVISWESFFTNALRQAGNEMETMISELVKDLLMRLERSTVPGVTCNIFLALTGLVNMTRSFIPSFATSCASNIITVLMNNYISLAGSPLSYSAHLMSEEVQFAARFALGHLAGCIVSNESLTRQMYDTLVEAATNSNTKSRPIDTAVDLVQFANGYAASHYLSALAVYPVATEHVQELKKTGIKALLRYSESAAVSDSRVLGILMGFASRLKAGNVEGDVLDFATQSLERYLTGSFVSKGRLFGSTWVCATGALQEHQVDYHLSNIIESTLAAASTDNGLAQHFYHFTVPYATVQYHNHLCSNTNEQAIIEFYQRAFEPLFHSIQSDDASSNYRVASLFAVGSLLGINYLSSFNRTAEIIVLEAQRYHALARRPGIDKLGVVAGLTVRSAPTGNLKSGRVAAAVCGKAIEHAKELLQTLKSDSSEPTDVDSPSSSAVLMASSSEPTSYNRLNSNTSYLKAIFEQLNQTTLPNTINMFLKSLIHTPGPLPPVNWFSLMLKLVKTQPEQCLQFASAHASTSFSLSEFLVMQTNSALSSTSQLCSILFEKTNAFGAILELAGLTVQINKTKDTKMRRGMNAIIKKIHLSESRLLELIDLIGQKFFYLTPSTQEALLITLKQHLPGNTRLKQEGEEKAQLIQSIRHTILQSITLPLLNNKESNXIILKSAVECSITQVNQLLHTGTSKDWSEMPVESMYTHLFSLCTLYRQQSDQKQLLVKHISAAISVLICRLGEIATTEMDPWHFWSVISSCISSDCPDLKETLGWIIRVLDAFVVFASTCNTSDSSHDQDLYDGIYIGLCQILSDLSSSFSHPSDNRLEAMETVYLLNAFILNANHHKTEQEQIVKRVFKLLDMTSKLQARLSAEFFECVVLGLPKEYINQNEWRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NJW3</accession>
    <name>A0A1C7NJW3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Nutrient and stress factor 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">USV1_1</name>
        <name evidence="12" type="ORF">A0J61_02525</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000096">
        <property type="protein sequence ID" value="OBZ89433.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NJW3"/>
    <dbReference type="STRING" id="101091.A0A1C7NJW3"/>
    <dbReference type="InParanoid" id="A0A1C7NJW3"/>
    <dbReference type="OrthoDB" id="10018191at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000433">
        <property type="term" value="P:carbon catabolite repression of transcription from RNA polymerase II promoter by glucose"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:002343">
        <property type="entry name" value="Zinc finger protein 33A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051007">
        <property type="entry name" value="creA/MIG_C2H2-ZnF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47428">
        <property type="entry name" value="REGULATORY PROTEIN MIG1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47428:SF2">
        <property type="entry name" value="ZINC FINGER PROTEIN RSV1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="7" id="KW-0804">Transcription</keyword>
    <keyword evidence="6" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 9" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="11">
        <location>
            <begin position="17"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="11">
        <location>
            <begin position="48"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="70"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="78"/>
            <end position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="OBZ89433.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="332" mass="38179" checksum="C64D3DC040DC4F04" modified="2016-11-30" version="1">MPNKRRTSGSRSAPKLFKCTGYGDCDMVFTRSEHLARHERKHTGEKPYKCIVPGCDRMFSRFDNMMQHTQTHEKNKKTLTTPMTNSNKRTHKSDNLIKKEPFKFKPNSNIAPLEGFSMINSRTLPLPTRRASIAAPYHTGPYHTSSTVPYYHSLSVPQSQYDPSHRSSWPLKRDLYPHQTYPPPHPYSRVMHEQEYYPRRRSSASTFSIDSPIISPISSTFPQTNEPQVRRRISVDELHLPIENLRDSPIDSKIHLKPIYSHNISKKNEIDITSDEYEALEGFSKFRSGTIESEVIDRTPSPKIGNASPNLASEVCAMRQRVMSLNESYQRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NK64</accession>
    <name>A0A1C7NK64_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_02577</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000098">
        <property type="protein sequence ID" value="OBZ89380.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NK64"/>
    <dbReference type="InParanoid" id="A0A1C7NK64"/>
    <dbReference type="OrthoDB" id="2256418at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="39"/>
            <end position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ89380.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="319" mass="36123" checksum="1366592AEE7203A4" modified="2016-11-30" version="1">MSSINDSDCLQAYFEQQNDTEAASIVAAVMALLPSHIHTDETEAELEAETEDIDTQEDAEQDQLMEYIDELNLHVAALETDLLTKESEIAALKEVASKWRSRALEIESNYHQLDIQSRRKLKSMQKRHEQSLEEKDNMIVYLKNKVDYLIATQQQYQDSVESEIYDGESDTDEQEWSSLTDNYQKELQPGAILDSIQDTMRAIEQELNFHALQSTAYNEPQPNLQDHTGPVDFGLSSSTIVDCSMTEKANKKKSFMHRMIKRGFSNNVPAANDVLVPETLLKKNKADAKAAEAAAAKKAELRKASTEQTMKIRVIEENS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NLV0</accession>
    <name>A0A1C7NLV0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Protein MEF2BNB</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">A0J61_02531</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Lysosome membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the BORCS8 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000096">
        <property type="protein sequence ID" value="OBZ89426.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NLV0"/>
    <dbReference type="InParanoid" id="A0A1C7NLV0"/>
    <dbReference type="OrthoDB" id="10044187at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019320">
        <property type="entry name" value="BORCS8"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21146:SF0">
        <property type="entry name" value="BLOC-1-RELATED COMPLEX SUBUNIT 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21146">
        <property type="entry name" value="MEF2B PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10167">
        <property type="entry name" value="BORCS8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0458">Lysosome</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="137"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004656"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010463"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023228"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OBZ89426.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="137" mass="15813" checksum="F0690B7CA8BDB1CF" modified="2016-11-30" version="1" fragment="single">TSSSSARSYSWTAAFSLDQLSLYSKKTFGEQEEKKKRRQQERIKQIAGGFNHILLLSLNDCSVGLYRVLDHIHRRIPKIVETKKKVRSSSQRVETAILDIEDVRKNVCELEQIESFFNISQMIEQSIAIVKKPTDIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NM95</accession>
    <name>A0A1C7NM95_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Sulfite oxidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">SOX</name>
        <name evidence="7" type="ORF">A0J61_03563</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mo-molybdopterin</name>
            <dbReference type="ChEBI" id="CHEBI:71302"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000156">
        <property type="protein sequence ID" value="OBZ88384.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NM95"/>
    <dbReference type="STRING" id="101091.A0A1C7NM95"/>
    <dbReference type="InParanoid" id="A0A1C7NM95"/>
    <dbReference type="OrthoDB" id="10051395at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030151">
        <property type="term" value="F:molybdenum ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043546">
        <property type="term" value="F:molybdopterin cofactor binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008482">
        <property type="term" value="F:sulfite oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006790">
        <property type="term" value="P:sulfur compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.420.10:FF:000002">
        <property type="entry name" value="sulfite oxidase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.650">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.420.10">
        <property type="entry name" value="Oxidoreductase, molybdopterin-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005066">
        <property type="entry name" value="MoCF_OxRdtse_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008335">
        <property type="entry name" value="Mopterin_OxRdtase_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000572">
        <property type="entry name" value="OxRdtase_Mopterin-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036374">
        <property type="entry name" value="OxRdtase_Mopterin-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19372:SF7">
        <property type="entry name" value="SULFITE OXIDASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19372">
        <property type="entry name" value="SULFITE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03404">
        <property type="entry name" value="Mo-co_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00174">
        <property type="entry name" value="Oxidored_molyb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00407">
        <property type="entry name" value="EUMOPTERIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="E set domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56524">
        <property type="entry name" value="Oxidoreductase molybdopterin-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0500">Molybdenum</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Oxidoreductase molybdopterin-binding" evidence="5">
        <location>
            <begin position="50"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="domain" description="Moybdenum cofactor oxidoreductase dimerisation" evidence="6">
        <location>
            <begin position="257"/>
            <end position="375"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001924"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022505"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00174"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF03404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OBZ88384.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="385" mass="43297" checksum="CF79B0E920708BE4" modified="2016-11-30" version="1">MSSLDYSQDPSHTSLPLIVRKEAPYNAEPTPSDLVKNYVTPEKYFFCRNHGPLPDIKEETHHIKIQGIGCLEPVEFSMKQLKHNYEKHSIMMAMQCAGNRRDGLHKVKHTKGVIWGPGALGNAVYSGCRLRDVLADVGVTSKISNMTKLHVAFESVEACEEDTCYGSSIPLSKALDEFGDVLLAYEMNYQTLSRDHGFPIRVVVPGYIGGRSVKYLKSITIQDHESFSFYQRRDYKILPENVSCEAQANDYWCKVPSIGEYNVQSYVCHPEDGLHKEPSMNQIVQGYALSGGGRSIQRVDVSGDDGKTWVVAQLHQPAAKDNNCRVWAWCLWTAVVATKRGVRIVSRATDSSGNIQQEYPVWNYRGVMNNAWRTVEPDKLNLSCL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NMG9</accession>
    <name>A0A1C7NMG9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_01720</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000058">
        <property type="protein sequence ID" value="OBZ90218.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NMG9"/>
    <dbReference type="InParanoid" id="A0A1C7NMG9"/>
    <dbReference type="OrthoDB" id="2263680at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ90218.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="343" mass="39410" checksum="C143F09A8DCB64D2" modified="2016-11-30" version="1">MMSIKDRRSRRSAVWKRMPHQLKGLLRKKEELKQSISSPSLLSSSSFDATSSSLVPSKVAFAKTKQPPLIHRLFPSTKNRHKAVLQIKKQQWDQTETEFDIYEPEGSICQQLMSFLSPSFEIAAEAVKQEGWPQCLTTEKLDEMSRIYMATLHKIRLLGHFSLEQQLSIHRLLSDLQYPTDNLQSIHQQSLHKKSLLARVPHQHPHLFQREFSSLLSGKAMIDSVLLPNRKPRRTRYIFMLLSTPVSHIKDGIHPITETLGKLRKPFAETSNVIIADELEDQHHASFVPAEYLLDPVTLHSNFYNKQPSPLYHRLETKLSCTTITQYLSSAEQNMAKLGIQTN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NMQ5</accession>
    <name>A0A1C7NMQ5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">ATPase family AAA domain-containing protein 5</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">Atad5</name>
        <name evidence="3" type="ORF">A0J61_01533</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000050">
        <property type="protein sequence ID" value="OBZ90422.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NMQ5"/>
    <dbReference type="STRING" id="101091.A0A1C7NMQ5"/>
    <dbReference type="InParanoid" id="A0A1C7NMQ5"/>
    <dbReference type="OrthoDB" id="9996895at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23389:SF21">
        <property type="entry name" value="ATPASE FAMILY AAA DOMAIN-CONTAINING PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23389">
        <property type="entry name" value="CHROMOSOME TRANSMISSION FIDELITY FACTOR 18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03215">
        <property type="entry name" value="Rad17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="2">
        <location>
            <begin position="155"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="30"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="34"/>
            <end position="49"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ90422.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="534" mass="62524" checksum="2F6969F656A72F6A" modified="2016-11-30" version="1">MSKKESLLTYFKVVKEQPTTNLVLEKQSLRNRDPQLSSRSSFLDSCTNHNSKKQLDNARPILSDKSNHNVPHYNMTNIDLQNDFATLMDQRYTKEWRRERCCQYLMHHASRNKGCLWKDKYMPDNIEGLIGQLKNYRYLLDWLNRLRTNTQQSNKSNIILLVGKHGIGKSASVQVAAKQAGYSVFEINSSSRRSGKNLLEKIGGMSESHLVRFQQMDPEKKRKFEQRETIIIRDRVKKPKMDITRHFKPIGSERKETAPKRAKIESNISKQDIVKSNYKASESLILLEEVDILFEEDKGFWQSLHAISQKSKRPIIMTCNNDTLDVPYDLLHLQTTLYFDPPSEDSLLPYLQLVCHLEGFEKVKRQDLSYIAELYEYDVRRILNALQLWLSNDTQKDLFAHIMGFSDLLSLHNSHSLADRLKGLNTTEKTICKRYFFERFGCASMSTIEEVDHLLEVYSFTDAYVGLSNQRMHQIYDTDQYQAEKNDMQYIKMIYKNPTGLDHWLVEETIEDFIYTSNYDWSDPSLNIQLKTTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NMX0</accession>
    <name>A0A1C7NMX0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="9">NADH-ubiquinone oxidoreductase 14 subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">nuo14.8</name>
        <name evidence="9" type="ORF">A0J61_01457</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
            <orientation evidence="1">Matrix side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the complex I LYR family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000046">
        <property type="protein sequence ID" value="OBZ90492.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NMX0"/>
    <dbReference type="STRING" id="101091.A0A1C7NMX0"/>
    <dbReference type="InParanoid" id="A0A1C7NMX0"/>
    <dbReference type="OrthoDB" id="14535at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045271">
        <property type="term" value="C:respiratory chain complex I"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006979">
        <property type="term" value="P:response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd20266">
        <property type="entry name" value="Complex1_LYR_NDUFA6_LYRM6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045299">
        <property type="entry name" value="Complex1_LYR_NDUFA6_LYRM6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016488">
        <property type="entry name" value="NADH_Ub_cplx-1_asu_su-6"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12964:SF0">
        <property type="entry name" value="NADH DEHYDROGENASE [UBIQUINONE] 1 ALPHA SUBCOMPLEX SUBUNIT 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12964">
        <property type="entry name" value="NADH-UBIQUINONE OXIDOREDUCTASE B14 SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13233">
        <property type="entry name" value="Complex1_LYR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006643">
        <property type="entry name" value="NDUA6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0249">Electron transport</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0679">Respiratory chain</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <keyword evidence="9" id="KW-0830">Ubiquinone</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009508"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022660"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OBZ90492.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="125" mass="14566" checksum="29C56F1156BE9E8A" modified="2016-11-30" version="1">MIQQGIFGVAEHAITTASAKSSSEATSRALGLYRKWQKSVPEMMKLHEINLPPSAIRAKIREEFEKHRHVEQLEVRDILFAKGQMEYQEVMNVWKQNNHIMNYFAKEEAPPKPTTFLEKFYEGRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NMX2</accession>
    <name>A0A1C7NMX2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative threonine-phosphate decarboxylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">cobD</name>
        <name evidence="2" type="ORF">A0J61_01721</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000058">
        <property type="protein sequence ID" value="OBZ90219.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NMX2"/>
    <dbReference type="STRING" id="101091.A0A1C7NMX2"/>
    <dbReference type="InParanoid" id="A0A1C7NMX2"/>
    <dbReference type="OrthoDB" id="2108at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00609">
        <property type="entry name" value="AAT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004839">
        <property type="entry name" value="Aminotransferase_I/II_large"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43799">
        <property type="entry name" value="AMINOTRANSFERASE, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43799:SF1">
        <property type="entry name" value="ASPARTATE AMINOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00155">
        <property type="entry name" value="Aminotran_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aminotransferase class I/classII large" evidence="1">
        <location>
            <begin position="35"/>
            <end position="369"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ90219.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="373" mass="42057" checksum="8B09735071C55277" modified="2016-11-30" version="1">MSNASNVWDAKTQAFHGGQEHRFLNNFVEDFSVTTNYLGTPQLALEAAKEAINEIHHYPAANQEPAKSCLAEFLWGSDYAQHHGRLLMGNGASELIDLVVRKALLSFSERGIKKPTWKGSPWNVQYREYQRSAETNGFEILDPSNPEKADMICIVNPCNPTGDYFSVEPLKNWIKDNVKSGGCVIVDESMQPWHSADFRNDSLISEHDFAKDMYVTESVSIHVMHSWTKIWSCTGLRIGSVICPTDAHCEALRKIQVPWSVNGPALKFVEAVVNDKGYLQETWDNTSRLRAYLVDQLKSLGHSEWEYHGKSFLSWVWLDMKDETLAAKAIDLARAAGVPVRSGKPGYQCNSFVRVAVRKEAQVHILIQAWKSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-06-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NMZ9</accession>
    <name>A0A1C7NMZ9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_01481</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000047">
        <property type="protein sequence ID" value="OBZ90477.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NMZ9"/>
    <dbReference type="InParanoid" id="A0A1C7NMZ9"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ90477.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="85" mass="9539" checksum="92B2287255126157" modified="2016-11-30" version="1">MLLPLFIAEGFQSMYWSCGQAIFLEGNFYLLSQVQFFPCLHRESQPFLYRLPFQIGSLATASGSFGFRGAATISNFAINCSMFFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NNL5</accession>
    <name>A0A1C7NNL5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_01225</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000036">
        <property type="protein sequence ID" value="OBZ90722.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NNL5"/>
    <dbReference type="STRING" id="101091.A0A1C7NNL5"/>
    <dbReference type="InParanoid" id="A0A1C7NNL5"/>
    <dbReference type="OrthoDB" id="18134at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034198">
        <property type="term" value="P:cellular response to amino acid starvation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042149">
        <property type="term" value="P:cellular response to glucose starvation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1904262">
        <property type="term" value="P:negative regulation of TORC1 signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061462">
        <property type="term" value="P:protein localization to lysosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3450.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038060">
        <property type="entry name" value="C12orf66-like_central_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018544">
        <property type="entry name" value="KICS_2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31581">
        <property type="entry name" value="KICSTOR COMPLEX PROTEIN C12ORF66"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31581:SF1">
        <property type="entry name" value="KICSTOR SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09404">
        <property type="entry name" value="C12orf66_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160651">
        <property type="entry name" value="FLJ32549 C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF158548">
        <property type="entry name" value="FLJ32549 domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ90722.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="446" mass="51276" checksum="574DC021BE815693" modified="2016-11-30" version="1">MEEDQYQSVLKALGAFDYIAANKLIPKLAKIYYPIGSIFTRLSSCESSFTQLQFLRSRWFVVRKDTSVEMVYTNLAQEIPKEIVHINSVTWLSPEDRHELVTMMEALRNLCLVRREMISIYQAILAQSSKGEFDEILKEVEIVQAKMEDMNLSSSLLLLGVGLEKEIHVLYCILKARTSVTNYSLQDTCIALYKGKQGLAEWKKICQEQDYPEKTSSKAENTKETSSLWRFSIFSQLDTKSASHKQGDIWPNTIRWYIQVLDNLAAKMTLYFNQILVEKQSIISEEDPEKALWKGIRIDYYDQICTFKKKQGADSVSLIYEVTSDTSFYPQGYICPNSSYQQPQGVHSFPFIFSHPKEPPTKYLPSIISIIQGSQHKLNDPKAGPVHFMDPTVGSTFYLMRIDRHVVFLIIFSEKTHSEPATIEFMTHIVTSLRGSTVIEKMLRID</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NP59</accession>
    <name>A0A1C7NP59_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">fructose-2,6-bisphosphate 2-phosphatase</fullName>
            <ecNumber evidence="2">3.1.3.46</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">FBP26_0</name>
        <name evidence="9" type="ORF">A0J61_01045</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">In the C-terminal section; belongs to the phosphoglycerate mutase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.46" evidence="2"/>
    <dbReference type="EMBL" id="LUGH01000029">
        <property type="protein sequence ID" value="OBZ90895.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NP59"/>
    <dbReference type="FunCoup" id="A0A1C7NP59">
        <property type="interactions" value="282"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NP59"/>
    <dbReference type="InParanoid" id="A0A1C7NP59"/>
    <dbReference type="OrthoDB" id="267323at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003873">
        <property type="term" value="F:6-phosphofructo-2-kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004331">
        <property type="term" value="F:fructose-2,6-bisphosphate 2-phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006003">
        <property type="term" value="P:fructose 2,6-bisphosphate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006000">
        <property type="term" value="P:fructose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07067">
        <property type="entry name" value="HP_PGM_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1240:FF:000005">
        <property type="entry name" value="GpmB, Fructose-2,6-bisphosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000644">
        <property type="entry name" value="GpmB, Fructose-2,6-bisphosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1240">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003094">
        <property type="entry name" value="6Pfruct_kin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013079">
        <property type="entry name" value="6Phosfructo_kin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013078">
        <property type="entry name" value="His_Pase_superF_clade-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029033">
        <property type="entry name" value="His_PPase_superfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10606:SF44">
        <property type="entry name" value="6-PHOSPHOFRUCTO 2-KINASE_FRUCTOSE 2,6-BISPHOSPHATASE LONG FORM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10606">
        <property type="entry name" value="6-PHOSPHOFRUCTO-2-KINASE/FRUCTOSE-2,6-BISPHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01591">
        <property type="entry name" value="6PF2K"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00300">
        <property type="entry name" value="His_Phos_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000709">
        <property type="entry name" value="6PFK_2-Ptase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00991">
        <property type="entry name" value="6PFRUCTKNASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00855">
        <property type="entry name" value="PGAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53254">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="6-phosphofructo-2-kinase" evidence="8">
        <location>
            <begin position="1"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="active site" description="Tele-phosphohistidine intermediate" evidence="6">
        <location>
            <position position="211"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor/acceptor" evidence="6">
        <location>
            <position position="281"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="210"/>
            <end position="217"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="261"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013067"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR613078-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR613078-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01591"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OBZ90895.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="470" mass="54071" checksum="98A633D9B9F696E5" modified="2016-11-30" version="1">MVGLPARGKTYISQKVCRYLTWLGIKTKVFNVGNYRRQLHGANLPHTFFDPHNSIGEQQRREAAAAALKDMIRWFNEDQGVVAIYDATNSTKARRQWLCEKLGRQDIQVLFIESICQDEELILANIKDVKLSSPDYVAMDPDEAAIDFRARIDHYKEQYETITEQELTYIKLINVGSQNVINQIQGYLESRIVYYLMNLHIAPRKIYFSRHGESQFNLLGKIGGDSNLSERGRLYASKLPDLIKTHLKDQSLTVWTSTMKRTIETSEQLNYPKLQWKALDELDAGVCDGMTYEEIEEKYPEDFANRDEDKFNYRYRGGESYGDVVLRLEPVIMELERHENILIIGHQAILRCIYAYFMNYSQEDLPYIKIPLHTVIELTPKAYGCEEKRFKVDIEAVDTHRPKVKRSTSIRKLMPSLKMPSLGASGEIVRDPVSPIIPISPQLFPKQSTSTNATVKTPLAKLDLGDAYMP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NPF5</accession>
    <name>A0A1C7NPF5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">SYO1-like TPR repeats domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">A0J61_00950</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the nuclear import and ribosome assembly adapter family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000025">
        <property type="protein sequence ID" value="OBZ91005.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="FunCoup" id="A0A1C7NPF5">
        <property type="interactions" value="79"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NPF5"/>
    <dbReference type="InParanoid" id="A0A1C7NPF5"/>
    <dbReference type="OrthoDB" id="288703at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006606">
        <property type="term" value="P:protein import into nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042273">
        <property type="term" value="P:ribosomal large subunit biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd13394">
        <property type="entry name" value="Syo1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000225">
        <property type="entry name" value="Armadillo"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052616">
        <property type="entry name" value="SYO1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057990">
        <property type="entry name" value="TPR_SYO1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13347">
        <property type="entry name" value="HEAT REPEAT-CONTAINING PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13347:SF1">
        <property type="entry name" value="HEAT REPEAT-CONTAINING PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00514">
        <property type="entry name" value="Arm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25567">
        <property type="entry name" value="TPR_SYO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00185">
        <property type="entry name" value="ARM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50176">
        <property type="entry name" value="ARM_REPEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="repeat" description="ARM" evidence="2">
        <location>
            <begin position="77"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="domain" description="SYO1-like TPR repeats" evidence="3">
        <location>
            <begin position="455"/>
            <end position="678"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00049983"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00259"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF25567"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OBZ91005.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="680" mass="75396" checksum="751BCFCAE182B443" modified="2016-11-30" version="1">MGKQVRSKQRRNLGSRVVAGAQQGIVDQQITLQPEQVIPVVQKLSSLDATERGWAASSISNLVLSSPSNLKLLLSRGVVGSLIQLLNDQSREVVEEALGTLRNLCAVDPDVTKEYFSKDILTPLSTLLPQISHIIDLVLSDAPITDAADQDRRGSIWDVAENYIYIIWSLSETSEKHIKAVNRLNIITFLISFLSAADKCPNKVVVAAGQCLTTLTDDNKDIYIEFQNHPEYTQTLLGVLTKSEGSDRLLVRVLACAILMNVREVVQLSGSWDDERDALGELHKIVLPPLMACLDYDIQKAAEEIKTIVDQGDITQHEDTTEITPKPKQPLTKGDLQLQHTEEQLVTLQLALELMADICAQDEAEDDGWEDAGEEMEEDEATEQMADNLNEDNVDQYLRDAENLGEGTSATVEESAIRSSPIVNNFTTNIYPRLLQLASPTPLSFSQDYPAGIRQGLALAHQRALECLNNFLLAMNEIPSKFWFKEHVADASATWAWLFGTAHTIGSAPESEERNDVLEAIVGCLWALGRGLGSQIPLEPTXVPTLCGAFRATQSESMQVKIVGTLGSIAVRQGDINTNKEIGTFVMDILSNIPTQKTKTDVAVEALNLMFDVYSDCAFDYDEPVFVQGKFNQQLKQILPAFRSMVKSTDKRKNFDLRNRCDEALMNLVAFIKYKTSERK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NPJ8</accession>
    <name>A0A1C7NPJ8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Tc1-like transposase DDE domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_00923</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000024">
        <property type="protein sequence ID" value="OBZ91037.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NPJ8"/>
    <dbReference type="InParanoid" id="A0A1C7NPJ8"/>
    <dbReference type="OrthoDB" id="2209160at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038717">
        <property type="entry name" value="Tc1-like_DDE_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46564">
        <property type="entry name" value="TRANSPOSASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46564:SF1">
        <property type="entry name" value="TRANSPOSASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13358">
        <property type="entry name" value="DDE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tc1-like transposase DDE" evidence="2">
        <location>
            <begin position="58"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="39"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13358"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ91037.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="247" mass="27376" checksum="899FF2D255AD1C3A" modified="2016-11-30" version="1">MTRGRAWSKKAEPAIEEMPSTKAVSKTALGAVSLSMRKAAGATKRKAPEDRLNLPKGTTSNHFMQSVVDTMDIMDQFPEMRGYHIVMDNAPIHVHNNVDPILICRGYTSVYLPPYSPKLNPIEQFWKDLKDYIKGDNFKGNEALTSRMMDACEKVSSRILTSVGTNFETDNLCNGPNECGIRGKRLAASSVGWWEGFRKGPKYSANIRVAGVVSIAVESAMCMTLHAGEATTVGFEELRKSEDLLRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NPL7</accession>
    <name>A0A1C7NPL7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">GATA-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">A0J61_00973</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000026">
        <property type="protein sequence ID" value="OBZ90958.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NPL7"/>
    <dbReference type="STRING" id="101091.A0A1C7NPL7"/>
    <dbReference type="InParanoid" id="A0A1C7NPL7"/>
    <dbReference type="OrthoDB" id="515401at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000122">
        <property type="term" value="P:negative regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00202">
        <property type="entry name" value="ZnF_GATA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.50.10:FF:000007">
        <property type="entry name" value="Nitrogen regulatory AreA, N-terminal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.50.10">
        <property type="entry name" value="Erythroid Transcription Factor GATA-1, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039355">
        <property type="entry name" value="Transcription_factor_GATA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000679">
        <property type="entry name" value="Znf_GATA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013088">
        <property type="entry name" value="Znf_NHR/GATA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10071:SF335">
        <property type="entry name" value="IRON-SENSING TRANSCRIPTIONAL REPRESSOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10071">
        <property type="entry name" value="TRANSCRIPTION FACTOR GATA FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00320">
        <property type="entry name" value="GATA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00619">
        <property type="entry name" value="GATAZNFINGER"/>
    </dbReference>
    <dbReference type="SMART" id="SM00401">
        <property type="entry name" value="ZnF_GATA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57716">
        <property type="entry name" value="Glucocorticoid receptor-like (DNA-binding domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00344">
        <property type="entry name" value="GATA_ZN_FINGER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50114">
        <property type="entry name" value="GATA_ZN_FINGER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0804">Transcription</keyword>
    <keyword evidence="5" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 8" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="GATA-type" evidence="9">
        <location>
            <begin position="24"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00094"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50114"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OBZ90958.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="257" mass="28879" checksum="9402084483F5647C" modified="2016-11-30" version="1">MEETHSNDCQGCRQCWQQNNIRWSPPVIKCSNCETTTTPLWRRNEAGNTICNACGLYFKLHNVQRPITMKRNVIKRRKRFNSIPQQLVVIENAPPPRSIAPSSPKRKRLSLPTHDHPMLPTVHSPIHSNTQNSETILSNIPSTIRQTLEAKRDTLQKELDHVTSLLSQTTEIMKTMESVMAIMNLQKPSPHGTITQEKLLLTSLMMLGLASNKSDKTIPSLSDAIPSLHHHHSSSSSISPSSSSFLSKYQLKTTTST</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NPS0</accession>
    <name>A0A1C7NPS0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Linear gramicidin synthase subunit D</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">lgrD_0</name>
        <name evidence="4" type="ORF">A0J61_01507</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000049">
        <property type="protein sequence ID" value="OBZ90436.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NPS0"/>
    <dbReference type="STRING" id="101091.A0A1C7NPS0"/>
    <dbReference type="InParanoid" id="A0A1C7NPS0"/>
    <dbReference type="OrthoDB" id="429813at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.10">
        <property type="entry name" value="ACP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="entry name" value="N-terminal domain of ligase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036736">
        <property type="entry name" value="ACP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051414">
        <property type="entry name" value="Adenylate-forming_Reductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_synth/lig_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013120">
        <property type="entry name" value="FAR_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009081">
        <property type="entry name" value="PP-bd_ACP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43439:SF2">
        <property type="entry name" value="ENZYME, PUTATIVE (JCVI)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43439">
        <property type="entry name" value="PHENYLACETATE-COENZYME A LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23562">
        <property type="entry name" value="AMP-binding_C_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07993">
        <property type="entry name" value="NAD_binding_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00550">
        <property type="entry name" value="PP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56801">
        <property type="entry name" value="Acetyl-CoA synthetase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47336">
        <property type="entry name" value="ACP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50075">
        <property type="entry name" value="CARRIER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Carrier" evidence="3">
        <location>
            <begin position="578"/>
            <end position="652"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OBZ90436.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="1060" mass="121267" checksum="074D85AD4D484A8F" modified="2016-11-30" version="1">MTLHQDYPSISLSDTQACVLYYKALINYVDSHLKLHAERILARYYSSQSDSFQTLTFADIDRMSINLACQWSDLAKEVHTISYIDDHSVAYLVVILAAMRLRKTFFLISPRNSQLHVTELLRKTGSKMLVTGKKYEAISQHSAAQAGEVHVLTITETDLDKWIHQPLELNFEDILNLEFSDNDIERSALIVHSSGSSSSPKPIYLSNRYLFYHLSQFYILIKNRPHLPQIGLEDVMLPIVPLFHCFGFFVAFTMISVGGSVVFMEKLPPSQNEINSALQINKVTMLCCPPIILEEMIPYLKQTNNFDAVQRLKYVIFGGAPFKMESGDWLRSHKINVRNMYGSTEMNGFLSSNLDPNSKTWNSLAPFRFDPQGESYGIFETVDESQPNIKHLYVRADCPTLATNISNRPDGGYDTDDLFREDPESPGYYIYLGRRNETLIMENGEKTNPLPMEATIREITVVKQVVVLGHERKCTSALIELDATKIENLQEEEVIESVHEAIELANRDCPSHSRILLEMVKVLPLGQTIPTTDKGNIKRKNAEQMYQHVIDELYDNFLNGSNKASCDAQSEEYKWTTEEMNDFLETNIAQVLRISKSLLKNHSQSIFDLGFNSLYAIQLRNYISKRFSKVSHNFLFENPTIDSMRNGLLQKEQPMIYTKQEKGYKNTQKLATCYIKQARVDFDPIVRTNYVAKEQVVLLTGATGSLGSFILECLLKDSRVKKVYCCVRGKQEDLKERLANSFKNRLLDITLLNSERVKVLPMKFSEQYLGLGETRYHALRKEVTLIQHCGWLLNFNMSLEHFDKECISPFYNLLKFAYHQQNPIHVHFVSSVSAGVLLGDTIEEEPYPFDARIAMPLGYAQSKFVVESLLNFMAKELNFPCFIERLGQVCGDTKNGIWNTSEQYPLMFIGGGSWMHKMPKLETGIDWIPVDFAAASIVDIMLNTRSSSTKVAQYVYHIVSPQSLKWCDILQSLTLAGMSFEVVDVEDWIKELIQNEENPAYRLIPFFEGNLRQTFKMPKWKTDKTMQATAVLSHVPALDVELFTKFLANWESTGFYNPSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NQH0</accession>
    <name>A0A1C7NQH0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_00605</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000014">
        <property type="protein sequence ID" value="OBZ91342.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NQH0"/>
    <dbReference type="InParanoid" id="A0A1C7NQH0"/>
    <dbReference type="OrthoDB" id="2290911at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ91342.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="228" mass="26220" checksum="944C2720DED964E0" modified="2016-11-30" version="1">MMTLKYRLAKLSRKISQSVHIYNDAVDILQLFRFTSNEMKHKATYESDELYEHRAFYRNKRFKFVDHPAFNHNTPKQLTSILIKPDRCDENKISLAQSRLASSITISSENLTAKEFADIAGITILPENEREFTSLEEDSISAINMDTLSSNNSYDLKPPQIWDSYFWSRPEDNLHRSNAQHIPSTLIGSTLAIEKEEVPRLHLAPSKSTVVIIKKGRFEICLGDNAKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NQS3</accession>
    <name>A0A1C7NQS3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Thermolabile hemolysin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_00489</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000011">
        <property type="protein sequence ID" value="OBZ91452.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NQS3"/>
    <dbReference type="InParanoid" id="A0A1C7NQS3"/>
    <dbReference type="OrthoDB" id="1600564at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016788">
        <property type="term" value="F:hydrolase activity, acting on ester bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1110">
        <property type="entry name" value="SGNH hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001087">
        <property type="entry name" value="GDSL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051058">
        <property type="entry name" value="GDSL_Est/Lipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036514">
        <property type="entry name" value="SGNH_hydro_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45648">
        <property type="entry name" value="GDSL LIPASE/ACYLHYDROLASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_4G14700)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45648:SF22">
        <property type="entry name" value="GDSL LIPASE_ACYLHYDROLASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_4G14700)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00657">
        <property type="entry name" value="Lipase_GDSL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52266">
        <property type="entry name" value="SGNH hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="272"/>
            <end position="288"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ91452.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="321" mass="36684" checksum="E34A54EEDCEC946F" modified="2016-11-30" version="1">MSQALDYITVYGDSYSDVQLATKRSNGPIWSEQLAKVWDTQLVSKATPGATFCSNTKPNGSWLQKQVHDDITLNSQDKSTVQIIFLGVTDLIETKGEATPHIKEWIRCIEDQIKFLYSLNPKSRIVVMGVPALEFSPYAMTHKSDTANLKQNIIEFNVALEEQILDWRTDVSDQIEFFDTYLAFSDVLGDPSVLHIEDVENAYWDRCQGQCVDPIDSYLWWDTIHLTGAGHKAISNTLQSKEFFQLQPISVEETGSMNELVPVIPQKYIRCVSWFMLGAIVVMIFYMFRHNRVVVSLKKRIQTKAAMMYSSSRNTHEYTLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NR35</accession>
    <name>A0A1C7NR35_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="8">SUN domain-containing protein 5</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">SUN5</name>
        <name evidence="8" type="ORF">A0J61_01063</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000030">
        <property type="protein sequence ID" value="OBZ90876.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NR35"/>
    <dbReference type="STRING" id="101091.A0A1C7NR35"/>
    <dbReference type="InParanoid" id="A0A1C7NR35"/>
    <dbReference type="OrthoDB" id="342281at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005635">
        <property type="term" value="C:nuclear envelope"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043495">
        <property type="term" value="F:protein-membrane adaptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.260">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045119">
        <property type="entry name" value="SUN1-5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012919">
        <property type="entry name" value="SUN_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12911:SF8">
        <property type="entry name" value="KLAROID PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12911">
        <property type="entry name" value="SAD1/UNC-84-LIKE PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07738">
        <property type="entry name" value="Sad1_UNC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51469">
        <property type="entry name" value="SUN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="88"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="domain" description="SUN" evidence="7">
        <location>
            <begin position="251"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="25"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="193"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="27"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="50"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51469"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OBZ90876.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="410" mass="47284" checksum="D2646952B14C486B" modified="2016-11-30" version="1">MSAFVRPPISEARLDTAEDYFERLEQPDSDDYIESDENEDNYESEQDDNTNVPQQDNNTSVSEQITISTGTQQYTYESIKQLFDHIPLFCWLFFAVFPLLVLLLSWLISSKEKPQVIPDNQVSQLRDKMSQLQEFFKSDMMNFEQENTQLASLLDEQKNTIQTLYKLLEQRVLDDVDTWLGVVLENQKQNLFQEDAAESSPSDQGDLPRESTFQPSQSDRLERIERIVASLPLLKQQEALQKPNFASFEHGARIFHAYTTSTYSPYGVLFEFLSDLLLAQKPEVVLLSDGREHSPWSMKGDKGALTIVLTESIEIQEVVLAHPHATLTTNEIQHAPKDIEILGIDYEEKMAYSLGNFTYHTEDTRGFLIDHKLLQNKLFNIVMIKIHSNWGNSFKTDIYRVRVHGNTRQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NR81</accession>
    <name>A0A1C7NR81_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Nuclear pore complex protein Nup85</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">Nup85</name>
        <name evidence="10" type="ORF">A0J61_00307</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Functions as a component of the nuclear pore complex (NPC).</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Component of the nuclear pore complex (NPC).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Nucleus</location>
            <location evidence="1 9">Nuclear pore complex</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the nucleoporin Nup85 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000006">
        <property type="protein sequence ID" value="OBZ91637.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NR81"/>
    <dbReference type="STRING" id="101091.A0A1C7NR81"/>
    <dbReference type="InParanoid" id="A0A1C7NR81"/>
    <dbReference type="OrthoDB" id="17644at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031965">
        <property type="term" value="C:nuclear membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031080">
        <property type="term" value="C:nuclear pore outer ring"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017056">
        <property type="term" value="F:structural constituent of nuclear pore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006406">
        <property type="term" value="P:mRNA export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045893">
        <property type="term" value="P:positive regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006606">
        <property type="term" value="P:protein import into nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011502">
        <property type="entry name" value="Nucleoporin_Nup85"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13373">
        <property type="entry name" value="FROUNT PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13373:SF21">
        <property type="entry name" value="NUCLEAR PORE COMPLEX PROTEIN NUP85"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07575">
        <property type="entry name" value="Nucleopor_Nup85"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 9" id="KW-0509">mRNA transport</keyword>
    <keyword evidence="7 9" id="KW-0906">Nuclear pore complex</keyword>
    <keyword evidence="8 9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5 9" id="KW-0653">Protein transport</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 9" id="KW-0811">Translocation</keyword>
    <keyword evidence="3 9" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004567"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005573"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022816"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023132"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU365073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OBZ91637.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="589" mass="68581" checksum="3FD7010C81373481" modified="2016-11-30" version="1">MNEEYIQNVYESQLKDAHVPTVRSTVKFASFASNLEIEIKESVKNYGNALQEYIDLIEQYYYPSEAKERETYKQLLYVWRLTELLQFDLAQQPLSEALMTWFNEAHRPLYFEYNKQAIIFDGALDRPDFWKFAIRMAVLGQLSQIALLFQHVLKNSQFAKLSQILAYILEVRNHIQHGHVDRENMQKTLISIQKTPFLDQVSRNHASQMISLMSVLLGDEKAILQHTTSDIHALVCLAYYQRTESIQALAQTFYSKHKQCPQSIARSLLTNDLYTAIEQGIQYDWWFLAHWTDLLHSSNRLDRPIQIQTGTGMVSLPVKNHFILYYASFLFNQCGLWKESFAYLLQCDDIGRSAIAKHLNNIDLTLEDEKIEDIVSFCQDYGFEQSLYQKKADLCLAQKNYAKSLNYYRLANQVGSIDQLFYDVIRHFAMTGQWIDLTYEQDGLYYTIYRSMLQIAASHEALDFSSAAHLFKQLIKQANIPSTLLPIIVWDNLTLVDDINFGYLDKQNLLDLKSLCQSFSKYAVPEDFELFCYHIQPKTDPYQQQQKPTLDQLIFSMNEFLDTSAVKISRAIERTLENTSKPYLPSISL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-06-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NS56</accession>
    <name>A0A1C7NS56_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_00083</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000002">
        <property type="protein sequence ID" value="OBZ91848.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NS56"/>
    <dbReference type="InParanoid" id="A0A1C7NS56"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ91848.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="59" mass="6916" checksum="00612E8A44784424" modified="2016-11-30" version="1">MKPRYSKSDPSKAVPSSYVIEINYLAFFSRNRSLLLHEIKNRLVPKHDAFSQMPYLICD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NSB4</accession>
    <name>A0A1C7NSB4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Peroxisomal membrane protein 4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">PXMP4</name>
        <name evidence="1" type="ORF">A0J61_00609</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000014">
        <property type="protein sequence ID" value="OBZ91346.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NSB4"/>
    <dbReference type="STRING" id="101091.A0A1C7NSB4"/>
    <dbReference type="InParanoid" id="A0A1C7NSB4"/>
    <dbReference type="OrthoDB" id="39659at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005778">
        <property type="term" value="C:peroxisomal membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019531">
        <property type="entry name" value="Pmp4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15460">
        <property type="entry name" value="PEROXISOMAL MEMBRANE PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15460:SF3">
        <property type="entry name" value="PEROXISOMAL MEMBRANE PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02466">
        <property type="entry name" value="Tim17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF013674">
        <property type="entry name" value="PXMP4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ91346.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="196" mass="22353" checksum="AD1158734176CEF8" modified="2016-11-30" version="1">MDTLDKIALHPYFHDLFSILKGCRNGMVYGAKVRFPHALVMTILFKSGSLESKVKGILMATKQHAQNLGLFATIYKTLMIVQRKLNGKEASIHPFIAGIIGGYYVFGENNSINQQIILYLFSRAVLAAVKVPVKRQIMDAPQQTYPVFAAVVWGCVMWLFRHETDTVQPSLRASMQYIYRDSDSWSSFKTLFWHNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NT52</accession>
    <name>A0A1C7NT52_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Rho GTPase-activating protein 15</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">ARHGAP15_1</name>
        <name evidence="6" type="ORF">A0J61_00051</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000001">
        <property type="protein sequence ID" value="OBZ91896.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NT52"/>
    <dbReference type="FunCoup" id="A0A1C7NT52">
        <property type="interactions" value="278"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NT52"/>
    <dbReference type="InParanoid" id="A0A1C7NT52"/>
    <dbReference type="OrthoDB" id="79452at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.60">
        <property type="entry name" value="Arfaptin homology (AH) domain/BAR domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.555.10">
        <property type="entry name" value="Rho GTPase activation protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027267">
        <property type="entry name" value="AH/BAR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031160">
        <property type="entry name" value="F_BAR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001060">
        <property type="entry name" value="FCH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050729">
        <property type="entry name" value="Rho-GAP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008936">
        <property type="entry name" value="Rho_GTPase_activation_prot"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000198">
        <property type="entry name" value="RhoGAP_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23176:SF134">
        <property type="entry name" value="RHO-TYPE GTPASE-ACTIVATING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23176">
        <property type="entry name" value="RHO/RAC/CDC GTPASE-ACTIVATING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00611">
        <property type="entry name" value="FCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00620">
        <property type="entry name" value="RhoGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00055">
        <property type="entry name" value="FCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00324">
        <property type="entry name" value="RhoGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103657">
        <property type="entry name" value="BAR/IMD domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48350">
        <property type="entry name" value="GTPase activation domain, GAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51741">
        <property type="entry name" value="F_BAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50238">
        <property type="entry name" value="RHOGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0343">GTPase activation</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-BAR" evidence="5">
        <location>
            <begin position="19"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="domain" description="Rho-GAP" evidence="4">
        <location>
            <begin position="331"/>
            <end position="528"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="160"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="170"/>
            <end position="191"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022468"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50238"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OBZ91896.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="531" mass="60272" checksum="6638B8860D546A0F" modified="2016-11-30" version="1">MMTTSTPNMFTEGNAHSIDLIGQMAELEGGLHALLEKVKGDSQVTKDISTFLKKRAFLEESYGRDMVKVAQSTAEAFDKAHPKSGTFGDVWISMLKVHEIIGNQRIKFATSISDLAEDLLSLGRNIEKDRKKIKDAGMHYEKLVSDADLQLEKSKQKFENTNEEWGRAVSQRNQEPTQPSKKNIFRSSRTPAQLDRTENDCRNKMDAADAQYKIQQKKTIQAHAEYYETHLPKILRDLKAVDDECNVALRYQLASYAYTFEQALTEDGLALDNDQGNGLRGLITKIDRESDWAEFVRLCTERSAKIQKADNIQHDHMVVNGHFANNRIFGVSLEQQAEMAEDMVPDILKQCATVVEKYALSSVGIYRLSGTSSKIQRLKYKFENGDPNPISEEDLSDINNVTGVLKLWFRELPDPLFPSATYHQFLEAAKLTDDRSRVIGLHTIINELSDAHYATLKYLMCHLHKVQSYQRFNKMGAANLATIFGLTLMSNESGSQMQMAIQDNQRFAESQLQAKVVQTILENYTEIFEEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NU61</accession>
    <name>A0A1C7NU61_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Isochorismatase domain-containing protein 2, mitochondrial</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">isoc2</name>
        <name evidence="3" type="ORF">A0J61_00899</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the isochorismatase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000024">
        <property type="protein sequence ID" value="OBZ91054.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NU61"/>
    <dbReference type="STRING" id="101091.A0A1C7NU61"/>
    <dbReference type="InParanoid" id="A0A1C7NU61"/>
    <dbReference type="OrthoDB" id="269496at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01012">
        <property type="entry name" value="YcaC_related"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.850:FF:000001">
        <property type="entry name" value="Isochorismatase domain-containing protein 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.850">
        <property type="entry name" value="Isochorismatase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000868">
        <property type="entry name" value="Isochorismatase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036380">
        <property type="entry name" value="Isochorismatase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050993">
        <property type="entry name" value="Isochorismatase_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14119">
        <property type="entry name" value="HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14119:SF3">
        <property type="entry name" value="ISOCHORISMATASE DOMAIN-CONTAINING PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00857">
        <property type="entry name" value="Isochorismatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52499">
        <property type="entry name" value="Isochorismatase-like hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Isochorismatase-like" evidence="2">
        <location>
            <begin position="14"/>
            <end position="161"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ91054.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="204" mass="22600" checksum="B7FEA01C962817AC" modified="2016-11-30" version="1">MSINKIAKLTPQTTALLVCDIQERFKGIIWQYPSVITVAGKMLKASKLLDMPVIVTEQYPKAFGPTVSELDISDAALRVEKTKFSMYIPEVIDVLKKTNTKSVLLLGIESHVCVLQTALEFLENDYDVHVLADAVSSQNHPEIDIAIARMRSAGAVITTSESVLFQLVKDAKHEKFKGVSGLVKEYMEASRVNKILLRHSSANL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NWH3</accession>
    <name>A0A1C7NWH3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_00218</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000004">
        <property type="protein sequence ID" value="OBZ91774.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NWH3"/>
    <dbReference type="STRING" id="101091.A0A1C7NWH3"/>
    <dbReference type="InParanoid" id="A0A1C7NWH3"/>
    <dbReference type="OrthoDB" id="672793at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ91774.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="233" mass="25976" checksum="67CB6FBED7CB7C91" modified="2016-11-30" version="1">MSLLRRQPILKQAVAQPYHQAISKQQRRPLSMWTIPKIILATTSKRNRGVILGTLGAASYLSSVMGPAVWVAAGGAASLFSWRLFRKTQKWWNYLSPILKSSDSQTEPSFSQAILSQIGTHRAAEVVRVEAIKSLKQYFSNSSRGKELLEQFGLDHPADLVWQDIHKSETERLEGNQHRVSSHFWLEDQTSSGPRGGSCEVTATAIVSGEGNIKLEQVKLSSPGWHQDEIIDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-06-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MTZ9</accession>
    <name>A0A1C7MTZ9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_11641</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01002288">
        <property type="protein sequence ID" value="OBZ80310.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="InParanoid" id="A0A1C7MTZ9"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="unsure residue" description="D or N" evidence="1">
        <location>
            <position position="7"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="94"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ80310.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="94" mass="10487" checksum="38E7E42AFE6F0330" modified="2016-11-30" version="1" fragment="single">GNIDCNDPKEFNCWXNNFVSVAQQYNIKAIKGNAKKVWCELVAPKAAKTCKRSLNQAVVVEDLEGLEKNLAVGEEAICTKFNEFRTAAIEDLKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MW66</accession>
    <name>A0A1C7MW66_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Serine-threonine kinase receptor-associated protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">strap_1</name>
        <name evidence="8" type="ORF">A0J61_11255</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="5">Belongs to the WD repeat STRAP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001833">
        <property type="protein sequence ID" value="OBZ80696.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MW66"/>
    <dbReference type="STRING" id="101091.A0A1C7MW66"/>
    <dbReference type="InParanoid" id="A0A1C7MW66"/>
    <dbReference type="OrthoDB" id="408728at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032797">
        <property type="term" value="C:SMN complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000387">
        <property type="term" value="P:spliceosomal snRNP assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19877">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19877:SF13">
        <property type="entry name" value="SERINE-THREONINE KINASE RECEPTOR-ASSOCIATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0418">Kinase</keyword>
    <keyword evidence="2" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="4" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="8" id="KW-0675">Receptor</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="8" id="KW-0808">Transferase</keyword>
    <keyword evidence="1 7" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="7">
        <location>
            <begin position="26"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="7">
        <location>
            <begin position="111"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="7">
        <location>
            <begin position="254"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038394"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00040390"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OBZ80696.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="305" mass="33886" checksum="6AD69AD274228B5B" modified="2016-11-30" version="1" fragment="single">PLVDFGRIDGNPMLRDGATGDWIGTFDGHKGAVWSARLSRKEAERAVTGSADFTAKIWDTRNGQTVHTFVHHHIVRAADFNGDSTKILTGGLEKKLRIFDLYRPDAAAMELIGHEGTIKAVVWDEARHAVLSAGEDSTVRIWDLRTMRQSGSIQTCPDAISTMTLSSDGQYVTWAAGKTANFWKPDSSFEDVKTVQTKEKTSSVSLHPNHQKFVAGSDEDLWVRIYDFKTGEVSGTLDLLCLVTDILTLKLEVYKGHHGPIHTVSYSPDGEIYATGSEDGTIRLWQTDPTKPYGLWQKNHPMENQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MWA1</accession>
    <name>A0A1C7MWA1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_10869</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001466">
        <property type="protein sequence ID" value="OBZ81082.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MWA1"/>
    <dbReference type="InParanoid" id="A0A1C7MWA1"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="148"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ81082.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="148" mass="17426" checksum="FF74412775B0D8DA" modified="2016-11-30" version="1" fragment="single">MPNIHQALSLYVQGNKEASLEDFFLTNLSCFAEHEFESLEVMRRKMKSGFVNAYKKYHPDTEVPEANHSTSFWANMFSYNKKTPEAIRTLMFKWYFALNEGRNEDFYAQNKEQVDDFLSTETSHPRILLDQMSVTMLKQFGQLKCNEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MWE6</accession>
    <name>A0A1C7MWE6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">A0J61_10828</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001425">
        <property type="protein sequence ID" value="OBZ81123.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7MWE6"/>
    <dbReference type="InParanoid" id="A0A1C7MWE6"/>
    <dbReference type="OrthoDB" id="2289680at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004190">
        <property type="term" value="F:aspartic-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016779">
        <property type="term" value="F:nucleotidyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00303">
        <property type="entry name" value="retropepsin_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.70.10">
        <property type="entry name" value="Acid Proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.10.10">
        <property type="entry name" value="HIV Type 1 Reverse Transcriptase, subunit A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001969">
        <property type="entry name" value="Aspartic_peptidase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043502">
        <property type="entry name" value="DNA/RNA_pol_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021109">
        <property type="entry name" value="Peptidase_aspartic_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050951">
        <property type="entry name" value="Retrovirus_Pol_polyprotein"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37984">
        <property type="entry name" value="PROTEIN CBG26694"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37984:SF5">
        <property type="entry name" value="PROTEIN NYNRIN-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50630">
        <property type="entry name" value="Acid proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56672">
        <property type="entry name" value="DNA/RNA polymerases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00141">
        <property type="entry name" value="ASP_PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0064">Aspartyl protease</keyword>
    <keyword evidence="5" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0540">Nuclease</keyword>
    <keyword evidence="2" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="4" id="KW-0645">Protease</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="34"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="41"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022750"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OBZ81123.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="431" mass="49242" checksum="4D30C4D0A259D405" modified="2016-11-30" version="1">MFNATASENKRDKIQHLIEDSLRLNACMKPTNVQRNERQNEQQNEQQNEQQNETGFSRPMKMNKNEKNAQNIVPTAMDIDSSDDESDLKFNAMTKMKVKMECKPNDPHFSKPPNDLLNTNCIYLPVIIENVKTIALLDTGSTFSVVSSSLAKFLKLEINDDIDDDKGYIMLGKSDVKVNRTGKTKEELKIFHNDIITYAKMEVFDVRDVHVVIGMDLMTSVGISISGIAYDWETPDHDIIPNPIDPNMYIPNDSPYGSKEERDKMINELQPYIDANANLDPRGHCTLPGSKIYLPLKPGIKSAYRRQYEIPMIYHDAVKEQVEKWKKHNVIEKAQPHTAFNDSLLVVKKKNAKXEYTGDIRVVIDCRLVNASMDTSKIDSFPLPLISDIHRKMGRSLRFKRVSIVNLPRLLSKMFSTLLEKHLSDSFLLAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MWN8</accession>
    <name>A0A1C7MWN8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Multiple myeloma tumor-associated protein 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">Mmtag2</name>
        <name evidence="3" type="ORF">A0J61_10722</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001341">
        <property type="protein sequence ID" value="OBZ81227.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MWN8"/>
    <dbReference type="InParanoid" id="A0A1C7MWN8"/>
    <dbReference type="OrthoDB" id="5390672at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019315">
        <property type="entry name" value="MMTA2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039207">
        <property type="entry name" value="MMTAG2-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14580:SF0">
        <property type="entry name" value="MULTIPLE MYELOMA TUMOR-ASSOCIATED PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14580">
        <property type="entry name" value="MULTIPLE MYELOMA TUMOR-ASSOCIATED PROTEIN 2 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10159">
        <property type="entry name" value="MMtag"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Multiple myeloma tumor-associated protein 2-like N-terminal" evidence="2">
        <location>
            <begin position="8"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="86"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="89"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="162"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="173"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="215"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="238"/>
            <end position="254"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF10159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ81227.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="272" mass="32364" checksum="83B27A267A643CC1" modified="2016-11-30" version="1">MFHPTRGGTRGGRDQFSWEDVKNDKHRENYLGHSLMAPVGRWQKGKDLTWYAKNNKDEEAKAKQSELAKIKEAEAEAMAIALGVRKKKTLESHVTEEDLKHALNKDNDDSEDDDHREAEGEKGLGYGKSSNRFLGIEEDRTMEVMNGSNDYNGIHHAAQQQIDHREEEDQSKRRSKKDHKHKKEKKKHKDSERRHHKDSRHRSRSPHRRRHDDRRRRDNSREDRRVSKERARHSRRRDSRERSHREHRKRDSSAQRRSLSPYSKRVLLSQNQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MWQ4</accession>
    <name>A0A1C7MWQ4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_10721</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001340">
        <property type="protein sequence ID" value="OBZ81231.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MWQ4"/>
    <dbReference type="InParanoid" id="A0A1C7MWQ4"/>
    <dbReference type="OrthoDB" id="2287593at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ81231.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="287" mass="33445" checksum="0FBE2EF4257EDD81" modified="2016-11-30" version="1" fragment="single">WNRGYPSLSIGRQDNHKSLLFICSDKTSSRPFHVHFILLLSLIHTVYSTALLNLSNTVDQTVVDTARFTRLLSNHLLFDHFDKAYTQLAKKISYQFRDAIQVKVKKTKSKSSAPKDVMLLPPVDVQILKPFIEDKLPAILTNRYDVNTLQNHIDQLLRSYCPQEQQMHLCILENKDIILRQVLQYTTQELQSTLYKVNEFDLPRLFEKTRAQISGILIHFNQHTMDSKYHRLELKIKSAQNTSLSDAVESRNRDWITPEMMQDFISTIHHTDAEEGYTIQDFLELAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MX62</accession>
    <name>A0A1C7MX62_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_10916</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001510">
        <property type="protein sequence ID" value="OBZ81036.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MX62"/>
    <dbReference type="InParanoid" id="A0A1C7MX62"/>
    <dbReference type="OrthoDB" id="5987805at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ81036.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="195" mass="21801" checksum="B6AC348E154A4911" modified="2016-11-30" version="1">MSCVPRSLTDSNAIEVRLTRGLAQSNNYMAGNSAAYIKHNVKTRDSEDEYNQLSTLITQNHEFEQLVILFSEMSIDTDDTADEFDNDFMCNSNPGEQETMFAGELTAKIVQDTDGVRIAPAEGSSPMSLLLDKDVESLAFPTLFDGSILDPKHKAASLSYNAIAKSLARHHDRRFANRTDFLLFMDRKKTIINIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MXE1</accession>
    <name>A0A1C7MXE1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Pre-mRNA-splicing factor 38</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="primary">tif223</name>
        <name evidence="17" type="ORF">A0J61_10470</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Acts as a component of the translation initiation factor 2B (eIF2B) complex, which catalyzes the exchange of GDP for GTP on the eukaryotic initiation factor 2 (eIF2) complex gamma subunit. Its guanine nucleotide exchange factor activity is repressed when bound to eIF2 complex phosphorylated on the alpha subunit, thereby limiting the amount of methionyl-initiator methionine tRNA available to the ribosome and consequently global translation is repressed.</text>
    </comment>
    <comment type="function">
        <text evidence="14">Required for pre-mRNA splicing.</text>
    </comment>
    <comment type="subunit">
        <text evidence="13">Component of the translation initiation factor 2B (eIF2B) complex which is a heterodecamer of two sets of five different subunits: alpha, beta, gamma, delta and epsilon. Subunits alpha, beta and delta comprise a regulatory subcomplex and subunits epsilon and gamma comprise a catalytic subcomplex. Within the complex, the hexameric regulatory complex resides at the center, with the two heterodimeric catalytic subcomplexes bound on opposite sides.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
            <location evidence="2">Cytosol</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1 14">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 14">Belongs to the PRP38 family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the eIF-2B gamma/epsilon subunits family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001190">
        <property type="protein sequence ID" value="OBZ81480.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MXE1"/>
    <dbReference type="FunCoup" id="A0A1C7MXE1">
        <property type="interactions" value="388"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7MXE1"/>
    <dbReference type="InParanoid" id="A0A1C7MXE1"/>
    <dbReference type="OrthoDB" id="10250549at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005851">
        <property type="term" value="C:eukaryotic translation initiation factor 2B complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005681">
        <property type="term" value="C:spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005085">
        <property type="term" value="F:guanyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002183">
        <property type="term" value="P:cytoplasmic translational initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd04198">
        <property type="entry name" value="eIF-2B_gamma_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd04652">
        <property type="entry name" value="LbH_eIF2B_gamma_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.10.10">
        <property type="entry name" value="Hexapeptide repeat proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="entry name" value="Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051960">
        <property type="entry name" value="eIF2B_gamma"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056764">
        <property type="entry name" value="LbH_EIF2B3/5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005835">
        <property type="entry name" value="NTP_transferase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005037">
        <property type="entry name" value="PRP38"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45989">
        <property type="entry name" value="TRANSLATION INITIATION FACTOR EIF-2B SUBUNIT GAMMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45989:SF1">
        <property type="entry name" value="TRANSLATION INITIATION FACTOR EIF-2B SUBUNIT GAMMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25084">
        <property type="entry name" value="LbH_EIF2B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00483">
        <property type="entry name" value="NTP_transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03371">
        <property type="entry name" value="PRP38"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 17" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="7 14" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="10 14" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="11 14" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 14" id="KW-0747">Spliceosome</keyword>
    <feature type="domain" description="Nucleotidyl transferase" evidence="15">
        <location>
            <begin position="18"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="domain" description="EIF2B subunit epsilon/gamma LbH" evidence="16">
        <location>
            <begin position="347"/>
            <end position="426"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004514"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00045373"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00046432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU367025"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF00483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF25084"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="OBZ81480.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="588" mass="66801" checksum="63BABB77E951501A" modified="2016-11-30" version="1">MLFEKPKHHHHRISEFQAVILAGYGSSNRLYPISEEENLPKALLPVGNKPVISYTLEWLEKAGIHDVIVVVQATGNAPQKLSAYLRTYTGNLHHQVVSVDEDDETADALRAIKDKIDRDFMVIPCDLITELDPRDFIDAHRVHDPTFSALYYAPGSTESASKDDDLLPYVGIDPVKNALVYKAIRSEDDDFSIRLSLLNKFPRVRIHTDLQDAHLYIFKRWIIDLRWIIDLVADKERITSISKDLIPMLVKCQYQQKMVEREHVDQYSCNYDDLLANALSLSTTQSDELDDFLVHPVLASFKSPIRSYVHIYRGGFCGRGNTSASYNELNRYTTKQGNPMTRVPSTAEVAPRTQVGNDSIIGEYTKIDEKSSVKKSCVGAHCIIGKNVKIANSVIMDHVVIGDNVKIDGCIICNNAQIHEKANMKDCDVAGGYIVDKEKNPNYHDGASIHGRHPLHLVEKIIRERIQGSLYWKEKCYGLSAATLMDRAVELEYIGGLYVRALGAFYLRLTGKSKEIYQYLEPLLNDYRKLRVRTGDGFTLSYMDSFIDDLLRESRVCDIILPRITSRYVLEQNDELEPRESALEDDLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MXJ9</accession>
    <name>A0A1C7MXJ9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">40S ribosomal protein S5</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">rps-5_3</name>
        <name evidence="4" type="ORF">A0J61_10399</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uS7 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001154">
        <property type="protein sequence ID" value="OBZ81553.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MXJ9"/>
    <dbReference type="STRING" id="101091.A0A1C7MXJ9"/>
    <dbReference type="InParanoid" id="A0A1C7MXJ9"/>
    <dbReference type="OrthoDB" id="10264639at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.455.10">
        <property type="entry name" value="Ribosomal protein S7 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000235">
        <property type="entry name" value="Ribosomal_uS7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036823">
        <property type="entry name" value="Ribosomal_uS7_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11205">
        <property type="entry name" value="RIBOSOMAL PROTEIN S7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47973">
        <property type="entry name" value="Ribosomal protein S7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4" id="KW-0689">Ribosomal protein</keyword>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OBZ81553.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="65" mass="7497" checksum="64CA59C6E887EBBD" modified="2016-11-30" version="1" fragment="single">MPALGLPTDVSATADGTRRLFNKWSYEDVEVKDISLQDYIQIRQQVYLPHTAGRFAVKRFRKAQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MYH5</accession>
    <name>A0A1C7MYH5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Retinol dehydrogenase 13</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">RDH13</name>
        <name evidence="2" type="ORF">A0J61_10060</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001018">
        <property type="protein sequence ID" value="OBZ81890.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MYH5"/>
    <dbReference type="STRING" id="101091.A0A1C7MYH5"/>
    <dbReference type="InParanoid" id="A0A1C7MYH5"/>
    <dbReference type="OrthoDB" id="191139at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05327">
        <property type="entry name" value="retinol-DH_like_SDR_c_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43157">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL-GLYCAN BIOSYNTHESIS CLASS F PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43157:SF73">
        <property type="entry name" value="WW DOMAIN-CONTAINING OXIDOREDUCTASE-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ81890.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="288" mass="32713" checksum="D9352044E9BFA0DD" modified="2016-11-30" version="1" fragment="single">FTEKTILITGASDGIGKETAIGLIKKNPKRLILACRESDKARQAKETIASLSSVTQVQLEWIDLADLASVQMCASRLIKQDILIDVLVNNAGVLTSQKYQTKDGFEMQFGTNYLGHFLLTELLLSHQRIQSDARIIQLSSHAMLFGHLDFDDLQCQHRRYSGWRAYTQSKLANVVYANHLQRIHPNLTTYSVHPGMVRTQFARHSGLFHLLDRLFYPIFYCLSNSPAEGASTSIYLASNDDPATRQGGLYWMNCKPFTMFKNKESQDVSVQEKLYIYSQEAVKDYTLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MYM4</accession>
    <name>A0A1C7MYM4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Helitron helicase-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_10445</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001176">
        <property type="protein sequence ID" value="OBZ81506.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MYM4"/>
    <dbReference type="STRING" id="101091.A0A1C7MYM4"/>
    <dbReference type="InParanoid" id="A0A1C7MYM4"/>
    <dbReference type="OrthoDB" id="2282872at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025476">
        <property type="entry name" value="Helitron_helicase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051055">
        <property type="entry name" value="PIF1_helicase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47642">
        <property type="entry name" value="ATP-DEPENDENT DNA HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47642:SF5">
        <property type="entry name" value="ATP-DEPENDENT DNA HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14214">
        <property type="entry name" value="Helitron_like_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helitron helicase-like" evidence="1">
        <location>
            <begin position="269"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="770"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF14214"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ81506.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="770" mass="89249" checksum="379565C0C0F978D5" modified="2016-11-30" version="1" fragment="single">MLQDPKDLIFPEILLEIEGLNKIEERLIAVRHVFQSIYSINVSVLPSSVKDTYIIATRLARKISDSHDYLQGNIRPNVVWESARNIKDMSLYKKLNITLNERWLPAATDNVQLNEVEHDASNSNSKDENLFDDLPVGCEESLFCSDNFLRLAPGEGYSASSIMRDEYVDFLAFPKIHAGHALEPMVNQKPMAYSAFTKSIIRLADRWGVVRDYLFFMDRKKLLLSLVNNTNIMMRKSSHSRLTAGGALNDVLVNNLIKTDRAFEVFKNIRQLGNPTLFITLSAAETKWEKLIVILKKVVDKEEITEDDAENLERREKYRLIQSNPVTCAQYFEYRFRELKQTWKPPHGPFGHHSVLDYYYRIEFQQRDSPHVHMLVWLEDAPTYSFCSDFGAENEQTVCDFIEQVISCKALSETENSTLSNLVKSRQHHKHTHTCWKNRRDGQKICRFNIPFFPMKSTCIITPLAELNATATDEKKKERLFLKQKVGDIKRYLTELADPSESNLTFEQFIETFELSEEQYTLAVRSSLKTKMQQSNMDIQFVFDPYVCCVYIVDYINKSDKGMSRVLQRVLREGIKDNAPTKNLLETIAAKYYNVCEILAQEAAYNLLLLRMTESSRAVIFVSTSPVESRARMMKSKEALQNLPESSTMSSAMECKLYSHHLIMLYLPWRDQLNEIDKQDCQSLFRQNKQAIEEAANEFSKLPDDTISRFMEMASNFNFEQDAQRNQDSEEVQAHVEENEVSELNDFSMYILPEDNEIRVSQEFTDGERS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MYN5</accession>
    <name>A0A1C7MYN5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_10049</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001014">
        <property type="protein sequence ID" value="OBZ81901.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MYN5"/>
    <dbReference type="STRING" id="101091.A0A1C7MYN5"/>
    <dbReference type="InParanoid" id="A0A1C7MYN5"/>
    <dbReference type="OrthoDB" id="4088568at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="677"/>
            <end position="697"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="256"/>
            <end position="297"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ81901.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="736" mass="84473" checksum="809EE5E7BF71124A" modified="2016-11-30" version="1">MSLKKQILRQHAGGHRTYKTALLSSSTMNDTAEKTIISTPSSLSPSMEESLQDWLSKSLPSGFLLSDVCLCCQRDDCQHFKAIANTIYKLENDVHLAAEAQVAPKSVLEIANFVIGQGLLQNHEQTVAETNLLRAKFKQEVSNCFLRSATLAKKEAFQERINELEYSLSESKYLKTDCDKERDRLAWELQRTQKSLEDTAADLESCNSRYLQLSTELKSKTIEIERLRIYESMAIESDANEELLRAKIKNYAIIQVGDLEQELSASKKNEQSLESKYKKLEAKYNSVSAEFDKLKATQKEMGITDENQVNMTWLRESNQKLRKDVLKLTYALLSPNAASDLQVTNSNQNDLVELIKELASANNKLKSDLLDCSNLLMECKSDLYAKSNPDEEQEYDDDELKVERRRKSLFNHLQDTNYVDSPIPMSIPNTAPENLQNKQDETVLPQDRMTPLSESHNTSPVIHHHYHYYMKKKMMSEKRKIKRKRSSVIEAEEGLISITPSSSCSSAKMVPDLSPPFHQLYKQVTLVLQRLQQTDIRALNRRLRRTFDIVELSTMSNTMIENILADVNTLKSQFSWIEDKSVLKQEQWIHDVSIVEFFPITDLVQSMLKEIGQLRTTMNDLQLEYVKKIEEVDSRFEKELLEKQKVLQQQVQSKSKNHSKSTHPIHWLSSLFSRHRSKPTISQSPPPPPPRQERSNSALHGSFYTHFLNTNSNSNISIYSNPVHPYSKPILIQSGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MYZ5</accession>
    <name>A0A1C7MYZ5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">dual-specificity kinase</fullName>
            <ecNumber evidence="2">2.7.12.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">DYRK4_1</name>
        <name evidence="14" type="ORF">A0J61_09962</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.12.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.12.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:10596"/>
            <dbReference type="Rhea" id="RHEA-COMP:10136"/>
            <dbReference type="Rhea" id="RHEA-COMP:20101"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:46858"/>
            <dbReference type="ChEBI" id="CHEBI:61978"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.12.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MNB/DYRK subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.12.1" evidence="2"/>
    <dbReference type="EMBL" id="LUGH01000984">
        <property type="protein sequence ID" value="OBZ81991.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MYZ5"/>
    <dbReference type="FunCoup" id="A0A1C7MYZ5">
        <property type="interactions" value="173"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7MYZ5"/>
    <dbReference type="InParanoid" id="A0A1C7MYZ5"/>
    <dbReference type="OrthoDB" id="9332038at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005856">
        <property type="term" value="C:cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004712">
        <property type="term" value="F:protein serine/threonine/tyrosine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd14210">
        <property type="entry name" value="PKc_DYRK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000112">
        <property type="entry name" value="Putative dual specificity tyrosine-phosphorylation-regulated kinase 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.10.30">
        <property type="entry name" value="DYRK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042521">
        <property type="entry name" value="DYRK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050494">
        <property type="entry name" value="Ser_Thr_dual-spec_kinase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24058">
        <property type="entry name" value="DUAL SPECIFICITY PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24058:SF22">
        <property type="entry name" value="DUAL SPECIFICITY TYROSINE-PHOSPHORYLATION-REGULATED KINASE 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 14" id="KW-0418">Kinase</keyword>
    <keyword evidence="5 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="13">
        <location>
            <begin position="705"/>
            <end position="1001"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="120"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="257"/>
            <end position="522"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="556"/>
            <end position="577"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="120"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="158"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="186"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="285"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="412"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="460"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="511"/>
            <end position="522"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="734"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008867"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00049003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00049308"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00051680"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="OBZ81991.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="1025" mass="115543" checksum="AB973602DF9F628A" modified="2016-11-30" version="1">MESTGISQSGIYEAFAEVDRLENKKITLKKQLDARRKSTSTVETKKTTFASPRLSTVNTKKPTDRKPSLLLQSRRQTLSGALTSQPLRKQSIHQETGLIKLADTLRDTLAVERRLAQQELLNNERKPKQKTEMIDKRRPSMTKEKIRSLEPPVRRRTLSSGAQKPDTPQASPLKSTLIDQQRRHSVATTRTTTASPRRKKSLKGAESPFTSEDEVTPATPHISAFKRRSILAAATAKARQQQQQQQQHCPEIVGADEAVTMSSGDEKLNKTTRLRKKSLASEPDLLSRRMSRTESLKEGLPTSPSMMAARMSRRKSVVKQESPVNPAAKKSSTKENGNTTGDEQPAKKNGGRKRGKTLPGSLAKPPTVQSLQLPPMKIEPIKLTIPKTTTKRAPKSPSIKATVSTKKRLSVSSINTPTPHSPSSSSSTDVPPKKSLSTRKAKGQSHLGITTSRRASLKTPSSVNSKPSPVSASPRVRPRSTRRQSLGVLETNKTSSIRMESEPEQPPITRKLSSAYSNSRKNSLVEDMTADKDKGRHRAISLREKLEAMVAQHAIHQDDPKLRGRSPSHYHTAGPSTLATDYLAQKVARKSQSYDVDEKYAQLLSAEDRARPQRIKDTLMMWDKEMVEAIIPGMPKTPAIAIKFYGHHLSPFEQSEIQSYPEIYFVGQHAKKFQALTDNPALNYGYDDERGDYKTIISDHLAYRYEILEELGRGSFGQVVKCYDHKTASTVAVKLIRNKKRFYAQARTEVKILSDLSRWDPEDRHHNVKMTDSFVFRSHLCIAFECLSMNLYEFIKVNNFQGFHITLIKRFTIQLLRSLSLLARHGVVHCDLKPENILLKHPTKSTIKVIDFGSSCLEHQRVYTYIQSRFYRSPEIILGLDYNTAIDMWSLGCIIAELYTGVPIFPGENEQEQLACIMEIMGPPEQELIQQSERRHLFFDRRGEPRAVTNSRGKRRRAGTKTLSQALRCNDALFLDFIQQCLQWDPSKRLNPEQAFHHEWIAQSARPVTVRNSPVVTPTQVEEQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MZ86</accession>
    <name>A0A1C7MZ86_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Citrate lyase subunit beta-like protein, mitochondrial</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">CLYBL</name>
        <name evidence="7" type="ORF">A0J61_09738</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000925">
        <property type="protein sequence ID" value="OBZ82215.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MZ86"/>
    <dbReference type="STRING" id="101091.A0A1C7MZ86"/>
    <dbReference type="InParanoid" id="A0A1C7MZ86"/>
    <dbReference type="OrthoDB" id="1773at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006107">
        <property type="term" value="P:oxaloacetate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.60">
        <property type="entry name" value="Phosphoenolpyruvate-binding domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005000">
        <property type="entry name" value="Aldolase/citrate-lyase_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011206">
        <property type="entry name" value="Citrate_lyase_beta/mcl1/mcl2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015813">
        <property type="entry name" value="Pyrv/PenolPyrv_kinase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040442">
        <property type="entry name" value="Pyrv_kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32308:SF0">
        <property type="entry name" value="HPCH_HPAI ALDOLASE_CITRATE LYASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32308">
        <property type="entry name" value="LYASE BETA SUBUNIT, PUTATIVE (AFU_ORTHOLOGUE AFUA_4G13030)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03328">
        <property type="entry name" value="HpcH_HpaI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF015582">
        <property type="entry name" value="Cit_lyase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51621">
        <property type="entry name" value="Phosphoenolpyruvate/pyruvate domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0456">Lyase</keyword>
    <keyword evidence="3 5" id="KW-0460">Magnesium</keyword>
    <keyword evidence="2 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HpcH/HpaI aldolase/citrate lyase" evidence="6">
        <location>
            <begin position="59"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="120"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="182"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="182"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="209"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR015582-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR015582-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF03328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OBZ82215.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="358" mass="39885" checksum="13C814DAF8F0E864" modified="2016-11-30" version="1">MMLNIKSLLHASRRAAPSINLTHYKCDFTKHINKNYLLCRAISTNSNGNTKANTTRSRRALFYVPGSDERKIHKSISVGADCIVYDLEDSVTVNKKGTARHMVIDALEASEHGKAEKAVRINAVGSGHELDDLNVILHTKRLQAIVIPKVQSAKDIQFVSRMIDSVAVESQRERIRLIASVESALGMMNIKEIVTADPRLDAVIFAAEDYCADLGLVRTKTREEMLFARQWIVNAAAAYGLQAIDLVCVDYQDSAALEEECEEGRRFGFAGKQAIHPDQIDIIQRKFLPNDSELDRATRILEGYELNSQKGVGAFTLDGKMIDMPVVKWAEKVIARAKAGGMTIPKREKNDTTNEKKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MZV9</accession>
    <name>A0A1C7MZV9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Ricin B lectin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_10009</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001001">
        <property type="protein sequence ID" value="OBZ81939.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MZV9"/>
    <dbReference type="STRING" id="101091.A0A1C7MZV9"/>
    <dbReference type="InParanoid" id="A0A1C7MZV9"/>
    <dbReference type="OrthoDB" id="9895617at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd23454">
        <property type="entry name" value="beta-trefoil_Ricin_GllA-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.80.10.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035992">
        <property type="entry name" value="Ricin_B-like_lectins"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000772">
        <property type="entry name" value="Ricin_B_lectin"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00652">
        <property type="entry name" value="Ricin_B_lectin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50370">
        <property type="entry name" value="Ricin B-like lectins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50231">
        <property type="entry name" value="RICIN_B_LECTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ricin B lectin" evidence="1">
        <location>
            <begin position="18"/>
            <end position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00652"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ81939.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="269" mass="30851" checksum="7DFBB23DED79425F" modified="2016-11-30" version="1">MESVDYFPEGFFFIRCKSQPFAMDVNGGSMVNDANIIIWPQKMVDSINQLWMHEEGFLINKKSGLVIDIRGGSIEREKSIIQYARKPGLAHNQRWTYQDGYIFPTSAPHLALDIRSSEFKNGNTVVLNTKNVHSKTQQWLIQPFENEKSKAELALLRPSPLQRTSTFPRQNELYDCYRMVYLEMGNNVTPQQLAGAAAFKGLKDYVNQVKSNQNQVIVADDHSREQVIQIVKREVAQVLEQKQIENINELVQQAVTVAESYFSQEYNAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MZW5</accession>
    <name>A0A1C7MZW5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">L-azetidine-2-carboxylic acid acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">ppr1</name>
        <name evidence="2" type="ORF">A0J61_09553</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000876">
        <property type="protein sequence ID" value="OBZ82397.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MZW5"/>
    <dbReference type="STRING" id="101091.A0A1C7MZW5"/>
    <dbReference type="InParanoid" id="A0A1C7MZW5"/>
    <dbReference type="OrthoDB" id="10264707at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046941">
        <property type="term" value="F:azetidine-2-carboxylic acid acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052742">
        <property type="entry name" value="Mito_N-acetyltransferase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43138">
        <property type="entry name" value="ACETYLTRANSFERASE, GNAT FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43138:SF1">
        <property type="entry name" value="N-ACETYLTRANSFERASE ACA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="33"/>
            <end position="208"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ82397.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="208" mass="23348" checksum="7E2F24820BDBC51A" modified="2016-11-30" version="1">MSTAYGKIPKPTSSVDLNTILPIKKTLRDGTETMIQTVDPNNPSLIDYLHARFNAEIEAGSTYPQESLMDSQGFRDYFLGSDAFVMSVDGLIEPDTSYNWQEKIVGMFYVKPNYPGRCSHICNGGFFVMDHYRGRGAGLMMGEAFKVLVPAIGYKASVFNLVFENNPASIAIWRRLGFEQIGRVPKAGRLRNSPDQLVDALVFYYDFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N0F0</accession>
    <name>A0A1C7N0F0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_09382</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000837">
        <property type="protein sequence ID" value="OBZ82567.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N0F0"/>
    <dbReference type="STRING" id="101091.A0A1C7N0F0"/>
    <dbReference type="InParanoid" id="A0A1C7N0F0"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="50"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="170"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="224"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="185"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="229"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="328"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ82567.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="328" mass="36325" checksum="5EE8A842445E5133" modified="2016-11-30" version="1" fragment="single">MSNEEEQASKETISKRPILAKYATSAHGEKKFPTLSSHFDKNLTIEKAKFEGSSNSSTPLPHPPISSASTPVMLPTTTAVTTATTATELTGPLTTSVTLPTTTPASAVITMPSQSTPLTSKPSNSALNATIKPKVEDRRVMNKRKKLPQMSGTATPSEVFHRNLVDAVSNVEDSDENEQYVYPYSGNNTDTTTGYLPNDPMHRTASSLYRPQSTRSFAHTIEQQEGINSQQQQQQQQQQQQQQQLLSQQPHQPSRKKSGYFLGDIFKPILFKSKSSTTIRPNSYNSTGYTNTNNEELLARPKLRNFIMDHSTDNFWYSSSDGKHSPPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N0T0</accession>
    <name>A0A1C7N0T0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 14">DNA repair protein REV1</fullName>
            <ecNumber evidence="14">2.7.7.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="primary">rev1</name>
        <name evidence="18" type="ORF">A0J61_09199</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18 19">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template-dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents. Involved in mitochondrial DNA mutagenesis.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="15">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="15">Binds 2 magnesium ions.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 14">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 14">Belongs to the DNA polymerase type-Y family.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.-" evidence="14"/>
    <dbReference type="EMBL" id="LUGH01000795">
        <property type="protein sequence ID" value="OBZ82755.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="FunCoup" id="A0A1C7N0T0">
        <property type="interactions" value="421"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N0T0"/>
    <dbReference type="InParanoid" id="A0A1C7N0T0"/>
    <dbReference type="OrthoDB" id="427711at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003684">
        <property type="term" value="F:damaged DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017125">
        <property type="term" value="F:deoxycytidyl transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003887">
        <property type="term" value="F:DNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070987">
        <property type="term" value="P:error-free translesion synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042276">
        <property type="term" value="P:error-prone translesion synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd17719">
        <property type="entry name" value="BRCT_Rev1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01701">
        <property type="entry name" value="PolY_Rev1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1490.100:FF:000001">
        <property type="entry name" value="DNA repair protein REV1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.10190:FF:000011">
        <property type="entry name" value="DNA repair protein REV1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1170.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.1490">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.20">
        <property type="entry name" value="5' to 3' exonuclease, C-terminal subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10190">
        <property type="entry name" value="BRCT domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.100">
        <property type="entry name" value="DNA polymerase, Y-family, little finger domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.1280">
        <property type="entry name" value="DNA repair protein Rev1, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001357">
        <property type="entry name" value="BRCT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036420">
        <property type="entry name" value="BRCT_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043502">
        <property type="entry name" value="DNA/RNA_pol_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036775">
        <property type="entry name" value="DNA_pol_Y-fam_lit_finger_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017961">
        <property type="entry name" value="DNA_pol_Y-fam_little_finger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025527">
        <property type="entry name" value="HUWE1/Rev1_UBM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053848">
        <property type="entry name" value="IMS_HHH_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012112">
        <property type="entry name" value="REV1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031991">
        <property type="entry name" value="Rev1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038401">
        <property type="entry name" value="Rev1_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001126">
        <property type="entry name" value="UmuC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45990">
        <property type="entry name" value="DNA REPAIR PROTEIN REV1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45990:SF1">
        <property type="entry name" value="DNA REPAIR PROTEIN REV1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16589">
        <property type="entry name" value="BRCT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00817">
        <property type="entry name" value="IMS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11799">
        <property type="entry name" value="IMS_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21999">
        <property type="entry name" value="IMS_HHH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16727">
        <property type="entry name" value="REV1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14377">
        <property type="entry name" value="UBM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036573">
        <property type="entry name" value="REV1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00292">
        <property type="entry name" value="BRCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52113">
        <property type="entry name" value="BRCT domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56672">
        <property type="entry name" value="DNA/RNA polymerases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100879">
        <property type="entry name" value="Lesion bypass DNA polymerase (Y-family), little finger domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50172">
        <property type="entry name" value="BRCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50173">
        <property type="entry name" value="UMUC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 14" id="KW-0227">DNA damage</keyword>
    <keyword evidence="11 14" id="KW-0234">DNA repair</keyword>
    <keyword evidence="4 14" id="KW-0237">DNA synthesis</keyword>
    <keyword evidence="10 14" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="9 15" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7 15" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 14" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="12 14" id="KW-0539">Nucleus</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 14" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="BRCT" evidence="16">
        <location>
            <begin position="44"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="domain" description="UmuC" evidence="17">
        <location>
            <begin position="216"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="220"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="319"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="320"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010945"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00020399"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022634"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00058985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PIRNR" id="PIRNR036573"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PIRSR" id="PIRSR036573-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS50173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="OBZ82755.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="888" mass="100932" checksum="4596A3F1112535D3" modified="2016-11-30" version="1">MSKGEGSKDPYAAINFGEFRKYMQNKQNKLKRQQKELSDQASQEQPQIFTGLSIHINGYTSPPSSELRRMILQHGGDYQHYLKKLSVTHIIATNLTHSKVKEFRSYKIVKPEWIVESIAAKRLLPWQNYRLVIISTKQKELGFTSTSGQILNNAILANEWARETSTVNPDFIKRYYETSRLHYLSTWKEELKDIVNQMQDKFRKDPNRITSLHRVVMHVDFDCFFASVGIKDRPELKDKPVAVSHSKSANEESSSDVASCNYIARSFGVKNGMPIGSARSLCPELQVIPYEFEKYRAISRQFYEILFSYADELQAVSVDEALLEVGSHITIPNSEQEEALASKIRSEIEQATGCQVSVGIGPNILLARMSTKKAKPAGQFVCRDIDQLLLEQHVIDLPGVGHATKEKLEMMGVKTISNLRNVPLSELQAKLGMKVGQTLYDFSRGVDNRSLTCCHQRQSVSAEVNWGVRFEDEQNQRTFVEGLSKEVSDRLIKHGVKGKTITLKVLKRKEGATEARKHLGHGIVDSYSKSYTLNDFTDDHKMINKHAYSMLQSFEFPFDDIRGLGIHVMKLDNTNDTSANDQSKLNFKPLPEQVTSVQPIATASVKEEMEVDLNVYSELPDSVQQELKLNYHLKFTEPKKAKVDAISHVPDTLLSELPPWSQIDPNFLLALPDNMREQVLQMYSNQNNTTNHTAPSSLTDDRTTIAKNKNTLTQIFQPSFSDITASAPARAETAVLTSSQNTLPYDVNVLNELPKEIYEELVAEHRRTKEKNKEQALEQPESFEYQKVILRNSEPTLQGMTDINDVRNLIRTWVSSFQDEPEPEDVETVSSYLIDLIHGSDLEKVQLLMLYIGYLTKDLIHWKKXLCDMEKAILEATIAIYGCPMQLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N163</accession>
    <name>A0A1C7N163_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transposon Ty3-G Gag-Pol polyprotein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">TY3B-G_4</name>
        <name evidence="3" type="ORF">A0J61_10847</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001441">
        <property type="protein sequence ID" value="OBZ81104.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N163"/>
    <dbReference type="STRING" id="101091.A0A1C7N163"/>
    <dbReference type="InParanoid" id="A0A1C7N163"/>
    <dbReference type="OrthoDB" id="5920460at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01647">
        <property type="entry name" value="RT_LTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.270:FF:000020">
        <property type="entry name" value="Transposon Tf2-6 polyprotein-like Protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.10.10">
        <property type="entry name" value="HIV Type 1 Reverse Transcriptase, subunit A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043502">
        <property type="entry name" value="DNA/RNA_pol_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050951">
        <property type="entry name" value="Retrovirus_Pol_polyprotein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000477">
        <property type="entry name" value="RT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041577">
        <property type="entry name" value="RT_RNaseH_2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37984">
        <property type="entry name" value="PROTEIN CBG26694"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37984:SF5">
        <property type="entry name" value="PROTEIN NYNRIN-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17919">
        <property type="entry name" value="RT_RNaseH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00078">
        <property type="entry name" value="RVT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56672">
        <property type="entry name" value="DNA/RNA polymerases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50878">
        <property type="entry name" value="RT_POL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Reverse transcriptase" evidence="2">
        <location>
            <begin position="114"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="470"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ81104.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="470" mass="53294" checksum="06B8892151224913" modified="2016-11-30" version="1" fragment="single">CSCVVGAGCSGVDCVRESLNDRFAALRSNQKEVYHVGLAQKYTETLEEDLGTEKKPVKTIYTADNITEVSGSTRIKGYRMNIYLKEGAVQVKARPFRLGWENQDTMDKYIDEMLELDLIEKPTGIFSSPSFLVDKRDGFKRCVIDYRKLNKLILCTKYPTPTVTELTEAYAGATVFTSCDCTSEYHQLELNPDHAEYTAFVTNRGVFKYKVLPMGISPGCSEFQRVVSDIFRDYIGKFVLVFLDDMLVYSKTQEVHVEHLRLVFEACERANLKLKRAKCTFMASSTTYLGHSLTSEGSTLADYNKEKILGFQRPESAALLRSFLGTCNYFRKYVRGYASIVVCLNKLTRKNTTFVWNEEHEAAFNTLKTVLCSEPVVLAYPARDRYFILYVDASNLGLGAVLTQVDDQESMANEKVVAYASRGLRGAESRYHIHHLEAMSVVWGIGYFKHFLKGTRFLLVVDNYEFGADL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N1A9</accession>
    <name>A0A1C7N1A9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Chitinase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_09545</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000874">
        <property type="protein sequence ID" value="OBZ82409.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N1A9"/>
    <dbReference type="InParanoid" id="A0A1C7N1A9"/>
    <dbReference type="OrthoDB" id="10254444at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070492">
        <property type="term" value="F:oligosaccharide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46066:SF2">
        <property type="entry name" value="CHITINASE DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46066">
        <property type="entry name" value="CHITINASE DOMAIN-CONTAINING PROTEIN 1 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008889420" description="Chitinase" evidence="1">
        <location>
            <begin position="21"/>
            <end position="86"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ82409.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="86" mass="9900" checksum="F713E6DC4F0C993B" modified="2016-11-30" version="1">MKLFSLLVAISVQLTTFVIANDQLPIHAQHQNSQHHLNVKHILAQHDKPDHSNAHTKQFKGETLAYVTPWNNRGYDIVKEFKGKFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N225</accession>
    <name>A0A1C7N225_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Zinc finger CCHC domain-containing protein 8</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">ZCCHC8</name>
        <name evidence="7" type="ORF">A0J61_08888</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000729">
        <property type="protein sequence ID" value="OBZ83061.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N225"/>
    <dbReference type="STRING" id="101091.A0A1C7N225"/>
    <dbReference type="InParanoid" id="A0A1C7N225"/>
    <dbReference type="OrthoDB" id="8026949at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071013">
        <property type="term" value="C:catalytic step 2 spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052115">
        <property type="entry name" value="NEXT_complex_subunit_ZCCHC8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006568">
        <property type="entry name" value="PSP_pro-rich"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13316:SF0">
        <property type="entry name" value="ZINC FINGER CCHC DOMAIN-CONTAINING PROTEIN 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13316">
        <property type="entry name" value="ZINC FINGER, CCHC DOMAIN CONTAINING 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04046">
        <property type="entry name" value="PSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00581">
        <property type="entry name" value="PSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="PSP proline-rich" evidence="6">
        <location>
            <begin position="212"/>
            <end position="262"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00581"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OBZ83061.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="382" mass="45070" checksum="CD13B830F2EA2F9B" modified="2016-11-30" version="1">MSLLRQQALDSLYNVLKTPDKYGDKFLVRITETPKDGLVSLDLLRNMAVVLNQYPVEYLAHCIPLDRQNRFTWNSDFSRVGLKELAHFFETNPYGFMQPEDQDQGDVFDEVLPVLYDHGKFYIDNEHTRFQAQDDEKKRSVYQYDLLDIEPLGKRNFDDLYLANTGAECFNCGSTEHGVSNCPLPKNMSRISRKKRELRENHARSLFNSPLLLHFEPGRLSDNLKEALGILKNREEPPYYANMRYYGYPPGYMKREDDPILKIYDGNGNEEEVPNTDKHIFFDSSHNKQTVEYPGLNLSSTQQDIDWHCQQQLNDYYQQLNAYQQQLDYQQQWEDYWRNQTWQWEEYNQNNSISYTPLTNKQTIITDDQSVDMDLSSDEDDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N237</accession>
    <name>A0A1C7N237_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">rRNA-processing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">CGR1</name>
        <name evidence="10" type="ORF">A0J61_10537</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 8">Involved in nucleolar integrity and required for processing of the pre-rRNA for the 60S ribosome subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 8">Nucleus</location>
            <location evidence="2 8">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the CGR1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001224">
        <property type="protein sequence ID" value="OBZ81414.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N237"/>
    <dbReference type="FunCoup" id="A0A1C7N237">
        <property type="interactions" value="4"/>
    </dbReference>
    <dbReference type="InParanoid" id="A0A1C7N237"/>
    <dbReference type="OrthoDB" id="277961at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005579">
        <property type="entry name" value="Cgr1-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03879">
        <property type="entry name" value="Cgr1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7 8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="5 8" id="KW-0698">rRNA processing</keyword>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="24"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="102"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="31"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="47"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="9">
        <location>
            <begin position="110"/>
            <end position="123"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007869"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU363084"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OBZ81414.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="123" mass="14225" checksum="6C112B601D3A48CC" modified="2016-11-30" version="1">MVAVTKNNSKANVGGVVDTVNKRVSGKNWKVQKSATVRNQQPKQLRRSWDQRSKERARNDAVKTLERQLKADKQAAKDAKKAVSLERKKMREEKERMDALAAKMSAKRLERLKRREARKKARI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N248</accession>
    <name>A0A1C7N248_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcription factor tau subunit sfc4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">sfc4</name>
        <name evidence="3" type="ORF">A0J61_08731</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000700">
        <property type="protein sequence ID" value="OBZ83225.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N248"/>
    <dbReference type="FunCoup" id="A0A1C7N248">
        <property type="interactions" value="797"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N248"/>
    <dbReference type="InParanoid" id="A0A1C7N248"/>
    <dbReference type="OrthoDB" id="9991317at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000127">
        <property type="term" value="C:transcription factor TFIIIC complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006383">
        <property type="term" value="P:transcription by RNA polymerase III"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039340">
        <property type="entry name" value="Tfc4/TFIIIC-102/Sfc4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23082:SF0">
        <property type="entry name" value="GENERAL TRANSCRIPTION FACTOR 3C POLYPEPTIDE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23082">
        <property type="entry name" value="TRANSCRIPTION INITIATION FACTOR IIIC TFIIIC , POLYPEPTIDE 3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13176">
        <property type="entry name" value="TPR_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0802">TPR repeat</keyword>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="214"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="248"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="467"/>
            <end position="500"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="37"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="532"/>
            <end position="571"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="543"/>
            <end position="557"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ83225.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="1036" mass="120174" checksum="4799589B74C041C6" modified="2016-11-30" version="1">MAKDKGKGKAVASAHNAIEDMDITSILSNAGLDAVPLEDDLAQEEQELDLEDDDDNDSLNEWIQEDQNSDNDSIDEELMNDDEIIKLLDKRTENRAKLKTGDAEEMQREIEEFDNNLALTTGIGAGRVKGQTKKRLLKGEIRLSDEEKRKLGQANALYINRNYGEAIDILQEIIQKNPKVHPAWNTLGLVHEELGNKELSLKLRMMGAHICNDASLWKELGQKSIENEAITQAIQCFTKVISLDPTDVDALWDRSFLYKQHGRVELAVEGFTKILDYLPHHFKVINELAQLFRKQGRTKEAIKLYEDAILYHTEHYADQVNDEEEDEEEFVDKLGYAEINMLSELYLILNDYYHSLDTIKTGLRLVQKRQNETWWQSHTDDDDEYLEEDEARTDFPLELRVRMGICRLYLNQVRLATRHFQYLLQYPSSTYPDLFQDIAYAYYDKRHYELALPVFQKIIDGADEIEVDLLVRTADCYRETSDLDTAVLFYLNVLEEQPDNLDVMMSLATVYEEQGNEEKALELVDYVMKKNRESRQQKKSSTHKQATAAQERISQSQEAKRNNKSKKASLFDESSNGLTIKEYYSRRKDETNRREEEKTYATLGLFSKLDELDEKIGPNTVDAERSLIREYIRTAQELWQEFSNTSVFYPSERSTRYQGFYAFRKARNTSRDTDNLNAEAHHMANRLRTRVKIEKKDQASQDQVDFDEEERHLREEEEKNASMIHASDFRGVSFDRWLYMILRYAYALAMSRRYQDSFNVLTKAINANVFYHDIPKKTTLYLAVIGCGIVGGNNELVQYGARWLCNFYQFRNDPYRIYQAVVDAGNKDATLYASQPQLKFLNRTIRLMDAVVSSKRKDQMKGDNRGASTEQIRLLDEEIQAMNMDPSTINEQDPKRYYHMPAYIPADTVKRMGIEAPDHVNPILLGFFADLVLLSKNPLAASLFNLRAYAVAPKDRLNTLSLGISFLHTAIQRKTDNRHLQIMQGMLFIFEYAKLSDHNQESEFNIARAFHLLGLTHLAIPHYEKWLIWFGTDFAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N2B7</accession>
    <name>A0A1C7N2B7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">serine--tRNA ligase</fullName>
            <ecNumber evidence="1">6.1.1.11</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Seryl-tRNA synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="primary">dia4</name>
        <name evidence="12" type="ORF">A0J61_08822</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.11" evidence="1"/>
    <dbReference type="EMBL" id="LUGH01000717">
        <property type="protein sequence ID" value="OBZ83128.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N2B7"/>
    <dbReference type="FunCoup" id="A0A1C7N2B7">
        <property type="interactions" value="343"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N2B7"/>
    <dbReference type="InParanoid" id="A0A1C7N2B7"/>
    <dbReference type="OrthoDB" id="10264585at2759"/>
    <dbReference type="UniPathway" id="UPA00906">
        <property type="reaction ID" value="UER00895"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004828">
        <property type="term" value="F:serine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006434">
        <property type="term" value="P:seryl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00770">
        <property type="entry name" value="SerRS_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="entry name" value="Bira Bifunctional Protein, Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.40">
        <property type="entry name" value="Serine-tRNA synthetase, tRNA binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002314">
        <property type="entry name" value="aa-tRNA-synt_IIb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006195">
        <property type="entry name" value="aa-tRNA-synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002317">
        <property type="entry name" value="Ser-tRNA-ligase_type_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015866">
        <property type="entry name" value="Ser-tRNA-synth_1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042103">
        <property type="entry name" value="SerRS_1_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033729">
        <property type="entry name" value="SerRS_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010978">
        <property type="entry name" value="tRNA-bd_arm"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00414">
        <property type="entry name" value="serS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11778">
        <property type="entry name" value="SERYL-TRNA SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02403">
        <property type="entry name" value="Seryl_tRNA_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00587">
        <property type="entry name" value="tRNA-synt_2b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001529">
        <property type="entry name" value="Ser-tRNA-synth_IIa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00981">
        <property type="entry name" value="TRNASYNTHSER"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="Class II aaRS and biotin synthetases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46589">
        <property type="entry name" value="tRNA-binding arm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50862">
        <property type="entry name" value="AA_TRNA_LIGASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="4 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2 12" id="KW-0436">Ligase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aminoacyl-transfer RNA synthetases class-II family profile" evidence="11">
        <location>
            <begin position="175"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="10">
        <location>
            <begin position="107"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="276"/>
        </location>
        <ligand>
            <name>L-serine</name>
            <dbReference type="ChEBI" id="CHEBI:33384"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="307"/>
            <end position="309"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="307"/>
        </location>
        <ligand>
            <name>L-serine</name>
            <dbReference type="ChEBI" id="CHEBI:33384"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="323"/>
            <end position="326"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="330"/>
        </location>
        <ligand>
            <name>L-serine</name>
            <dbReference type="ChEBI" id="CHEBI:33384"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="394"/>
            <end position="397"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="445"/>
        </location>
        <ligand>
            <name>L-serine</name>
            <dbReference type="ChEBI" id="CHEBI:33384"/>
        </ligand>
    </feature>
    <feature type="site" description="Important for serine binding" evidence="8">
        <location>
            <position position="447"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00031113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR001529-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR001529-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="OBZ83128.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="487" mass="55460" checksum="27B53FCF8EC5D8D0" modified="2016-11-30" version="1">MLTFSVCRSRLTRHLPRTWICLRPYSSSPADTDIHRIPPQLNLEYYVQHTDALARNMQLRNYDSDSIYRVRDLYQQRQALQSQTNSLVDARDKVNAQIRQSSTKEERQQHIVKAKEWKDQIRQLEEQLVQVDLSLTEQALQIPNETHPNTPLGAEDQARIIKTVGSPRSSTGLLDHVAIADKLDMIEFEQAALVTGSKFYYLKNDGAWLEFALIQYAMHKAASRGFAPVLAPDMVRTSIAYGCGFQPRKKEASQIYDVTTQSTVGTSAPKLCLVGTAEIPLAGLSAQKLYREEELPKRIVGFSHAFRAEAGHGSAEERGLYRVHQFSKVELFTVTTPEQSERMMEEMRALQEDIFTELGLCFRVLDMPTEELGASAYRKYDMEAWMPGKNGWGEISSTSNCTDYQTRRLDIRYLSKDFKDSVGSKDVRVPWHIKEKWVHHCHTLNGTAMAVPRVIIALLETHQRPDGTVDVPLPLRKWIPGEPSVLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N2H4</accession>
    <name>A0A1C7N2H4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Methyltransferase-domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_10398</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001154">
        <property type="protein sequence ID" value="OBZ81554.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N2H4"/>
    <dbReference type="STRING" id="101091.A0A1C7N2H4"/>
    <dbReference type="InParanoid" id="A0A1C7N2H4"/>
    <dbReference type="OrthoDB" id="413520at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019410">
        <property type="entry name" value="Methyltransf_16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14614">
        <property type="entry name" value="HEPATOCELLULAR CARCINOMA-ASSOCIATED ANTIGEN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10294">
        <property type="entry name" value="Methyltransf_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ81554.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="372" mass="42398" checksum="B8E85A8D972B7B78" modified="2016-11-30" version="1">MTIQYIRFLKPPPTECLIGQHFTIVWTIESDLGDQTYWETVPVIISLQGSPQLGLRELTADPKIKSKKKAVFKPYAQTKPGLSTDVPVVFDPMRGGGIVTQLVIEQLPGKPVEIGQQVSIQLCLSLAPVVRSEPTSHPVWHEAYQFQSSLWIVPAWSCPILTTAAKQRHREVSESSDQAERWIKLPKQRQLQIKEDAVQSIARHVWDCGLGMCQFLFEQAMDTVFDEVVELGSGTGLVGIYAAELLKTHHVYLTDLPDALEIMQQNIVSQDKLSVRELAWGGKRDEDYSRVNLVLLTDVLYNQSSHDVLLETLDWLLDNKDCKALLAFKERNPDEREFFVKVESRGWQCERVLNQEHLVCEIYWIQKNPSYA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N315</accession>
    <name>A0A1C7N315_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Integrase catalytic domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_08437</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000649">
        <property type="protein sequence ID" value="OBZ83513.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N315"/>
    <dbReference type="STRING" id="101091.A0A1C7N315"/>
    <dbReference type="InParanoid" id="A0A1C7N315"/>
    <dbReference type="OrthoDB" id="10267344at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015074">
        <property type="term" value="P:DNA integration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043502">
        <property type="entry name" value="DNA/RNA_pol_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001584">
        <property type="entry name" value="Integrase_cat-core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050951">
        <property type="entry name" value="Retrovirus_Pol_polyprotein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37984">
        <property type="entry name" value="PROTEIN CBG26694"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37984:SF5">
        <property type="entry name" value="PROTEIN NYNRIN-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00665">
        <property type="entry name" value="rve"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56672">
        <property type="entry name" value="DNA/RNA polymerases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50994">
        <property type="entry name" value="INTEGRASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Integrase catalytic" evidence="1">
        <location>
            <begin position="65"/>
            <end position="177"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50994"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ83513.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="206" mass="23254" checksum="4E071C4EC207EA7C" modified="2016-11-30" version="1">MQDHTAHVKSVIDELTRVKLILSPAKCHFAQRAIYLLGFCVSANGQAYLGPRNITNTMEWPTPRTAEAVVQALIPVFCDLGIPRIVQSDNGKEFANQVMERFRKSTGFDHRLITPYYPQANGPAERTVGTAMNTIKKVVEGVTGEWDLFVYSVQLAINNKVSKRLNTPPLNVMFSRRLNDFKNYNEETGTTTPLIKEQADQRIKEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N3B6</accession>
    <name>A0A1C7N3B6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Protein dopey-1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">Dopey1</name>
        <name evidence="12" type="ORF">A0J61_08433</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Golgi apparatus membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the DOP1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000648">
        <property type="protein sequence ID" value="OBZ83517.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="FunCoup" id="A0A1C7N3B6">
        <property type="interactions" value="171"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N3B6"/>
    <dbReference type="InParanoid" id="A0A1C7N3B6"/>
    <dbReference type="OrthoDB" id="297643at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005768">
        <property type="term" value="C:endosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005802">
        <property type="term" value="C:trans-Golgi network"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006895">
        <property type="term" value="P:Golgi to endosome transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040314">
        <property type="entry name" value="DOP1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056457">
        <property type="entry name" value="DOP1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007249">
        <property type="entry name" value="DOP1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056459">
        <property type="entry name" value="TPR_DOP1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056458">
        <property type="entry name" value="TPR_DOP1_M"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14042">
        <property type="entry name" value="DOPEY-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14042:SF24">
        <property type="entry name" value="PROTEIN DOPEY-1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24598">
        <property type="entry name" value="DOP1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04118">
        <property type="entry name" value="Dopey_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24601">
        <property type="entry name" value="TPR_DOP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24597">
        <property type="entry name" value="TPR_DOP1_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0653">Protein transport</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="domain" description="DOP1 N-terminal" evidence="8">
        <location>
            <begin position="54"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="domain" description="DOP1-like middle TPR" evidence="9">
        <location>
            <begin position="351"/>
            <end position="564"/>
        </location>
    </feature>
    <feature type="domain" description="DOP1-like TPR" evidence="11">
        <location>
            <begin position="1036"/>
            <end position="1189"/>
        </location>
    </feature>
    <feature type="domain" description="DOP1-like C-terminal" evidence="10">
        <location>
            <begin position="1402"/>
            <end position="1894"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="570"/>
            <end position="608"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1499"/>
            <end position="1527"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="570"/>
            <end position="584"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="590"/>
            <end position="608"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="1499"/>
            <end position="1512"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="1513"/>
            <end position="1527"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004395"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00046326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF04118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF24597"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF24598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF24601"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="OBZ83517.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="1918" mass="220164" checksum="75D1EE3E693C891F" modified="2016-11-30" version="1">MADNENLLSISHKLLKKISNINASDTNSDISDNMDSSPEMTRNQLYIEQAYQNDPRFRKYVQLVEKNLQSFDAVNEWADIISFLGRLLKSFQAYPQFSIIPRKQLVAKRLAQCLNPGFPAGVHQKTLDVYAFILKTIGSDQLAIDLALWSTGLFPFVQYAATHVKPQLLNIFETHYLPLHSKLRPAMRGFVIALLPALEEEGSEFFDKVVILIEKLSETVELPFFYSCMWLIMISNPALRPPALNYLLRKLPKIVDREAVAVVLGGRENISLMIRAFAATLHDHQLLVQRGLLELLVQNFVLKHCMIPHEDLVILMRAALGIVLRKDMSLNRRLYAWLLGSDGKTQTQISYFNQYAEKAATHAVRGMLQQHPHNQKLDVEQQQRPYKILISLMDKWELGQPIVHHVFMDAIISIKSQKQDQVELLKTANMWMDMVEPYLICYKLFETVDDAFSNTRKSIPERLESLRLIEFTLDSFKLADDEVQQIHFPFMVAALTRQLKDSLSNPTFIENLPVVNQAIVLVLLLLARLPESIYLEKASEHREKDEKKRFEYDMNILDYVREFYHLNRSTHHDAETSNKEKGENEEIGDLSNTKKTPQPQPIQFQPRSGYSSLHGQVFVKEITENLTSFLIEFVNSYIVLPQDLLKGVDVGAEGIHLKDIEHELERVYLGICSAITSVAKYADDQFELTGSDALTSALLKCCQETSLFGIVDTGITTMTYLARIKRFIKPSVLQQTKHIKAIMDRLWGFLTPSMELLHMRTVELLWLLTDVSQPSQIETIISNYLIQKGNDQDPHVNLNRFGVVWELSENIPEASTVFTRPIFLILDLLREGTCSLDRSAGEAWVKTYLRNYVRLLRPFLTTMLDKHILRRTAKLDVDWKNQLLRKKPSSDKITEIVYSMYIRSFDTDILDYMLTTLITLVNFGGSKVLKACKQHLVDMEGSVGTSAQQILDIDTTKPVSFLDLLVLISLKFLETEPSAATIETLDKPVRSIQLHAADLLYLIISRLDFVNMTLVQQIQTHVLQKLLFCITTGHLKLQSKLLHLLHASLAITSATTQQGTKELVQHQRRPSSDSTHSNAATIINHGEAVTLMQNQSELFVKCVTDALTLSSNRALLSSYIDFILATLPYIKYGFKCMLVPTLMCICHQISLRCDTIEIAIHEKPTSCAFTEKDIMMLLTGLEKILMFCLTERVINDDWLKSTGDLPMPRIPEQSVLIGLAQVMHDPESYAHYKPRDVIVYHLPIVLEILVNTWRXFRRPQWDEATTQAMGEAKVEAMLHSFSYAADQAKGRLEITFEKLFKYSIADFIEGLIEIFYIENPTALELDQTQDHHMTTLDVLSCTPTSTPQHIITTLLDSIRQRTPGAYQQRRRKIIRQGKLSDTSILRFAEIYCGHIKNPESIVLLWPMIHSFSKDYLSQASAFKLFLPGLMRFLTVSLEELTKANDYDHERRVRKDAQELYQRCVDYCILIAGKSFDQSLWIRGRSATLYDDPSILDDTSSTHTNDSNESHAASNQNSIPSHNNSSIISSADNTARNVSISNVLDMEKKASWKVREDVMISQVNQYLANQVIPRLRLLVGDNDKINSLLNNLVYYVIGPLLKSKVKSPIVLDQLCEMARMPFTYKTWRKEVWEVFIDPRFFYMNSTAARKWMTIIHTAFSIEKERMTELMARITTTPSTAFFSNKDVETLNRSLNLRRLSFVLFSGTMDQYVPQLPMIQEKMVELLKLDHSEMVHTEIYLCLRVILMRFSQKHLSNFWPVLITELMRLYNSFLHHDFQDRPEEAQIALAGCKYLDLLCTLELDAFQIYQWIFIRDTVETLIKPQTEEPIPMMESLTQKISNQSNDAFDFSFSETHMQPSLGSLKRPMLTMRNISSIRQLSFFVEHVGLYVYQSSFTLSKPDLPFIESLLLGDLLEEEGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N3B8</accession>
    <name>A0A1C7N3B8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">PAS domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">A0J61_08375</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000638">
        <property type="protein sequence ID" value="OBZ83571.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N3B8"/>
    <dbReference type="STRING" id="101091.A0A1C7N3B8"/>
    <dbReference type="InParanoid" id="A0A1C7N3B8"/>
    <dbReference type="OrthoDB" id="411251at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000977">
        <property type="term" value="F:RNA polymerase II transcription regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.20">
        <property type="entry name" value="PAS domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013655">
        <property type="entry name" value="PAS_fold_3"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00229">
        <property type="entry name" value="sensory_box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23043">
        <property type="entry name" value="HYPOXIA-INDUCIBLE FACTOR 1 ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23043:SF17">
        <property type="entry name" value="PROTEIN SIMILAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08447">
        <property type="entry name" value="PAS_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00091">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="PYP-like sensor domain (PAS domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50112">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="PAS" evidence="6">
        <location>
            <begin position="1"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OBZ83571.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="269" mass="31212" checksum="C8A87EC1986DC9A1" modified="2016-11-30" version="1">MRNNWITIFDNTPEARIVYTSESITDHTGWEPEELIGKEAYELFHPGDHKSLRKVHVANVYNEKMSCMVVYRFLHRDGHYITIETIIHCCHDVIVGSNYLYDENALDHKMRANSVDEIFICLANGSLQLAGAWNDRQERMEKTLSMEKVWVDHHIILKQERRFCLILNRFAEALNIVYASSLASELVALNVPLAIGTSLYEYVPERDFQSIQAQIDMAKEHDMVIRVRFDWVIDREKGLSEPVEAIVNSTDDGLVMVLRLSPRLFLDEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N3H4</accession>
    <name>A0A1C7N3H4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Arrestin C-terminal-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_08365</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000636">
        <property type="protein sequence ID" value="OBZ83587.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N3H4"/>
    <dbReference type="STRING" id="101091.A0A1C7N3H4"/>
    <dbReference type="InParanoid" id="A0A1C7N3H4"/>
    <dbReference type="OrthoDB" id="2333384at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.640">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014752">
        <property type="entry name" value="Arrestin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011022">
        <property type="entry name" value="Arrestin_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050357">
        <property type="entry name" value="Arrestin_domain-protein"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11188">
        <property type="entry name" value="ARRESTIN DOMAIN CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11188:SF17">
        <property type="entry name" value="FI21816P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02752">
        <property type="entry name" value="Arrestin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Arrestin C-terminal-like" evidence="2">
        <location>
            <begin position="184"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="344"/>
            <end position="363"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02752"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ83587.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="400" mass="45244" checksum="B8CE3A3FA219E30B" modified="2016-11-30" version="1">MNSLIGARNNHLDFNILFYPQYQNEHGQVVCHPGSVFEGIVQVKVGVPIQVHHIKLVFKASERVNYDAMGWEKSKLTDDRLFAVRTILWGLPAGVDVPPSAWPILEAGEYTFPFVCQMPMINFPPTFHHHLIATAFNMIVSVDKANETTPILSKPFPVQFQPTIETIPIKNLHAFTETSKLTNHVNAQVSVPRLAYNVNDTNQAISVTIQFSSLEDEQSLNLSQLRVYLKRYYSINYKSFSRSEATIVAHYDHPKLPSTCPSTVNMKLNLPSNQDELPATLVYSPHLTIEYKLVVVAKVRHGPIHIKKKLFDLPVMFGTLPAGTRAPRLLEPYSAIVENRSSMHSKPQFIRPEPRAQDEEEFLPPYNSDSVPPAYNNLLNNANLYPDRTASTSSLRIQIY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N3I1</accession>
    <name>A0A1C7N3I1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="14">TATA-box-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">tbp1</name>
        <name evidence="14" type="ORF">A0J61_10057</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the SLC35F solute transporter family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the TBP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001017">
        <property type="protein sequence ID" value="OBZ81894.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N3I1"/>
    <dbReference type="FunCoup" id="A0A1C7N3I1">
        <property type="interactions" value="155"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N3I1"/>
    <dbReference type="InParanoid" id="A0A1C7N3I1"/>
    <dbReference type="OrthoDB" id="429955at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005667">
        <property type="term" value="C:transcription regulator complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006367">
        <property type="term" value="P:transcription initiation at RNA polymerase II promoter"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd04516">
        <property type="entry name" value="TBP_eukaryotes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.310.10:FF:000001">
        <property type="entry name" value="TATA-box-binding protein 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.310.10:FF:000002">
        <property type="entry name" value="TATA-box-binding protein 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.310.10">
        <property type="entry name" value="TATA-Binding Protein"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00408">
        <property type="entry name" value="TATA_bind_prot_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037185">
        <property type="entry name" value="EmrE-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009262">
        <property type="entry name" value="SLC35_F1/F2/F6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052221">
        <property type="entry name" value="SLC35F_Transporter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000814">
        <property type="entry name" value="TBP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030491">
        <property type="entry name" value="TBP_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012295">
        <property type="entry name" value="TBP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033710">
        <property type="entry name" value="TBP_eukaryotic"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14233">
        <property type="entry name" value="DUF914-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14233:SF4">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 35 MEMBER F2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06027">
        <property type="entry name" value="SLC35F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00352">
        <property type="entry name" value="TBP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00686">
        <property type="entry name" value="TIFACTORIID"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103481">
        <property type="entry name" value="Multidrug resistance efflux transporter EmrE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55945">
        <property type="entry name" value="TATA-box binding protein-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00351">
        <property type="entry name" value="TFIID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="9 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0804">Transcription</keyword>
    <keyword evidence="6 13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 13" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="232"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="286"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="317"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="344"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="378"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="415"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="444"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="470"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="14">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007863"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="OBZ81894.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="526" mass="58696" checksum="376B6D2A4ABC6C54" modified="2016-11-30" version="1" fragment="single">PFALPTTPAPNDAPTPSRDANPHAVAGITPTLQNIVATVNLDCRLDLKTIALHARNAEYNPKRFAAVIMRIRDPKTTALIFASGKMVVTGAKSEDDSKLAARKYARIIQKLGFQAKFTDFKIQNIVGSCDVKFPIRLEGLAYSHGHFSSYEPELFPGLIYRMVKPKIVLLIFVSGKIVLTGAKVREEIYQAFQAIYPVLTEFLLSLCITGTNVTTTQINQQYQFSAPTTQTFLVYAVLATVYNSYALYKRGLRGWLMQFRQRGIHYFILGLIDVEGNYFVVKAYQYTSLLSAMLLNCWSTPVCMILSYFVLKSRFRWLQCAGVAIALGGMGMLIASDVMEGKDYAALDAVKGDLFCLLGATLYGFSNVGEEYMARKHPLYEVIGMFTFFATFINFVQLMILERHEFGSFSSNPGAAGMVVVYTFCMFILYSLAPVLFRMGSAVLYNLSLLTSNFYGLIFGIGLFGYHITVMYPIAYVIIIVGIAIYHLFPYHPPKEEVDNRSVQSNDAPEIIITQSDTSLDRKPGP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N3J3</accession>
    <name>A0A1C7N3J3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">5'-AMP-activated protein kinase subunit gamma</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">cbs2_1</name>
        <name evidence="6" type="ORF">A0J61_08346</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the 5'-AMP-activated protein kinase gamma subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000633">
        <property type="protein sequence ID" value="OBZ83607.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N3J3"/>
    <dbReference type="STRING" id="101091.A0A1C7N3J3"/>
    <dbReference type="InParanoid" id="A0A1C7N3J3"/>
    <dbReference type="OrthoDB" id="286637at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031588">
        <property type="term" value="C:nucleotide-activated protein kinase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016208">
        <property type="term" value="F:AMP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019901">
        <property type="term" value="F:protein kinase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019887">
        <property type="term" value="F:protein kinase regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd04618">
        <property type="entry name" value="CBS_euAMPK_gamma-like_repeat1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd04641">
        <property type="entry name" value="CBS_euAMPK_gamma-like_repeat2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.580.10">
        <property type="entry name" value="CBS-domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050511">
        <property type="entry name" value="AMPK_gamma/SDS23_families"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000644">
        <property type="entry name" value="CBS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046342">
        <property type="entry name" value="CBS_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13780">
        <property type="entry name" value="AMP-ACTIVATED PROTEIN KINASE, GAMMA REGULATORY SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13780:SF35">
        <property type="entry name" value="LD22662P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00571">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00116">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54631">
        <property type="entry name" value="CBS-domain pair"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51371">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0129">CBS domain</keyword>
    <keyword evidence="6" id="KW-0418">Kinase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="CBS" evidence="5">
        <location>
            <begin position="16"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="5">
        <location>
            <begin position="88"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="5">
        <location>
            <begin position="164"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="5">
        <location>
            <begin position="236"/>
            <end position="290"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006750"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OBZ83607.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="290" mass="32688" checksum="15CFFD50113481EA" modified="2016-11-30" version="1">MNEFLKQHTCYDVLPISFKLVVFDTQLTVKKALGILVQNGIVSAPLWSSEKQEYAGMLTVSDFISLIQYYYTNPKLQQEIDHLRIYQLTKQDMTLSAHPTTTLFDAAVLMSQTRAHRIPLIDHGQTTMIVSILTQYRLLKFIASNFKQSETLKTPLAELKIGTYGSHVATAFMSTPVIQIIQLLANLNISAVPIVDENGTVLNLYDTIDVMSLVRSEKYSGLDLPVSEILKSRPKDYPGVCTCTLNDTLYSIFKAIRRKRVYRLVVIEPETFKLIGLLSLSDILGHIVTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N3K4</accession>
    <name>A0A1C7N3K4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Ubiquitin-conjugating enzyme E2 27</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">UBC27</name>
        <name evidence="6" type="ORF">A0J61_08368</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the ubiquitin-conjugating enzyme family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000637">
        <property type="protein sequence ID" value="OBZ83578.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N3K4"/>
    <dbReference type="FunCoup" id="A0A1C7N3K4">
        <property type="interactions" value="1032"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N3K4"/>
    <dbReference type="InParanoid" id="A0A1C7N3K4"/>
    <dbReference type="OrthoDB" id="9993688at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070628">
        <property type="term" value="F:proteasome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004842">
        <property type="term" value="F:ubiquitin-protein transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036503">
        <property type="term" value="P:ERAD pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006511">
        <property type="term" value="P:ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016050">
        <property type="term" value="P:vesicle organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd23800">
        <property type="entry name" value="UBCc_UBE2K"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.110.10">
        <property type="entry name" value="Ubiquitin Conjugating Enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000608">
        <property type="entry name" value="UBC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023313">
        <property type="entry name" value="UBQ-conjugating_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016135">
        <property type="entry name" value="UBQ-conjugating_enzyme/RWD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24068">
        <property type="entry name" value="UBIQUITIN-CONJUGATING ENZYME E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00179">
        <property type="entry name" value="UQ_con"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00212">
        <property type="entry name" value="UBCc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54495">
        <property type="entry name" value="UBC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00183">
        <property type="entry name" value="UBC_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50127">
        <property type="entry name" value="UBC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <keyword evidence="2 4" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="UBC core" evidence="5">
        <location>
            <begin position="4"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="active site" description="Glycyl thioester intermediate" evidence="3">
        <location>
            <position position="90"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU362109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OBZ83578.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="165" mass="18468" checksum="38048EC8D149DE5A" modified="2016-11-30" version="1">MPPNMHKRILNEIEDVNSDNTAPLFVYVPQESNMYHIIGSIEGPPDSPYEGGTFLLDINLNDNHPFGPPNIKFITKVYHPNVSSQTGAICLDVLKSNWSPAMTLRTSLMSIQALLDAPDASSPQDYQVAKVYTADFPEFLNEAKLWTRTYANQSLNAYIDATFEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N3L9</accession>
    <name>A0A1C7N3L9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 13">Cytidine deaminase</fullName>
            <ecNumber evidence="4 13">3.5.4.5</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8 13">Cytidine aminohydrolase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="15" type="primary">CDA_0</name>
        <name evidence="15" type="ORF">A0J61_08235</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 13">This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>2'-deoxycytidine + H2O + H(+) = 2'-deoxyuridine + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:13433"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15698"/>
            <dbReference type="ChEBI" id="CHEBI:16450"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="EC" id="3.5.4.5"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9 13">
            <text>cytidine + H2O + H(+) = uridine + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:16069"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16704"/>
            <dbReference type="ChEBI" id="CHEBI:17562"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="EC" id="3.5.4.5"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 12 13">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3 13">Belongs to the cytidine and deoxycytidylate deaminase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.5.4.5" evidence="4 13"/>
    <dbReference type="EMBL" id="LUGH01000616">
        <property type="protein sequence ID" value="OBZ83712.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N3L9"/>
    <dbReference type="FunCoup" id="A0A1C7N3L9">
        <property type="interactions" value="549"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N3L9"/>
    <dbReference type="InParanoid" id="A0A1C7N3L9"/>
    <dbReference type="OrthoDB" id="414540at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004126">
        <property type="term" value="F:cytidine deaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042802">
        <property type="term" value="F:identical protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006216">
        <property type="term" value="P:cytidine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006217">
        <property type="term" value="P:deoxycytidine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008655">
        <property type="term" value="P:pyrimidine-containing compound salvage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd01283">
        <property type="entry name" value="cytidine_deaminase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.140.10:FF:000008">
        <property type="entry name" value="Cytidine deaminase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.140.10">
        <property type="entry name" value="Cytidine Deaminase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002125">
        <property type="entry name" value="CMP_dCMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050202">
        <property type="entry name" value="Cyt/Deoxycyt_deaminase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006262">
        <property type="entry name" value="Cyt_deam_tetra"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016193">
        <property type="entry name" value="Cytidine_deaminase-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01354">
        <property type="entry name" value="cyt_deam_tetra"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF004064">
        <property type="entry name" value="PRK05578.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11644">
        <property type="entry name" value="CYTIDINE DEAMINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11644:SF2">
        <property type="entry name" value="CYTIDINE DEAMINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00383">
        <property type="entry name" value="dCMP_cyt_deam_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53927">
        <property type="entry name" value="Cytidine deaminase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51747">
        <property type="entry name" value="CYT_DCMP_DEAMINASES_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 13" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5 12 13" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 12 13" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="CMP/dCMP-type deaminase" evidence="14">
        <location>
            <begin position="9"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="10">
        <location>
            <position position="63"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="50"/>
            <end position="56"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="61"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="94"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="97"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00003949"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012783"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00032005"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00049558"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR606262-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR606262-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR606262-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU364006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="OBZ83712.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="143" mass="15705" checksum="47824C38C75DCF68" modified="2016-11-30" version="1">MVSTTLSKEDQSKLFELALDAKNASYSPYSKFRVGAALLTEDGTFFKGCNVENASYGGAICAERTAYVKAVSEGHRKFRALAVSTDQEECISPCGICRQFISEFGSHEMPVYLLNTNGEYKVVTVAELLPFAFGLEHLENAKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N3S4</accession>
    <name>A0A1C7N3S4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">V-type proton ATPase subunit H</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">VATH_0</name>
        <name evidence="7" type="ORF">A0J61_08158</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the V-ATPase H subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000603">
        <property type="protein sequence ID" value="OBZ83795.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N3S4"/>
    <dbReference type="FunCoup" id="A0A1C7N3S4">
        <property type="interactions" value="560"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N3S4"/>
    <dbReference type="InParanoid" id="A0A1C7N3S4"/>
    <dbReference type="OrthoDB" id="10263554at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000329">
        <property type="term" value="C:fungal-type vacuole membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000221">
        <property type="term" value="C:vacuolar proton-transporting V-type ATPase, V1 domain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046961">
        <property type="term" value="F:proton-transporting ATPase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.150">
        <property type="entry name" value="V-type ATPase, subunit H, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004908">
        <property type="entry name" value="ATPase_V1-cplx_hsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011987">
        <property type="entry name" value="ATPase_V1-cplx_hsu_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038497">
        <property type="entry name" value="ATPase_V1-cplx_hsu_C_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10698">
        <property type="entry name" value="V-TYPE PROTON ATPASE SUBUNIT H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10698:SF0">
        <property type="entry name" value="V-TYPE PROTON ATPASE SUBUNIT H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11698">
        <property type="entry name" value="V-ATPase_H_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03224">
        <property type="entry name" value="V-ATPase_H_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF032184">
        <property type="entry name" value="ATPase_V1_H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="4 5" id="KW-0406">Ion transport</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ATPase V1 complex subunit H C-terminal" evidence="6">
        <location>
            <begin position="354"/>
            <end position="466"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRNR" id="PIRNR032184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF11698"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OBZ83795.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="470" mass="54034" checksum="5BE900EF089862CC" modified="2016-11-30" version="1">MLSAVEHSDTYVQLQTSAVSDAQLLAQNELIEEIRTTIISHPYLDDKLKALKETMVPWSEYEKIGLITADEVAMIEHVENKTAEELVPIMAEHGLYYAALYLDLMHKLARVDTLQKVLVLIHDMLDEHEERIELFHQAGSKVTDFPFGPFHKALRIGDEFIGIQSSKILTLLICSTSQRDIDIYEFFRWITFQLQSPHQHIIDLNIQILDALFHIPEYREAFWKTTHAIDSLVNTLRKTQEKNAGPQKIYEIMFALWLLTFNKTIAENLDRKCRIIPTLVSLAKFAVKEKVVRVVIATFKNLIEKAPAENIPAMLVAKLLPLCEHLGTRKWNDQEITEDIVFVQEELQKNFQSLTTFEVYASELETGMLQWSPSHSSENFWKQNAHKLNDNDQLLLKQLSRLLSSSTDPVVLAVACHDIGQYVKYSTSDGKKYLQALGAKQRIMELMTHQDPNVRYQALCATQKYFAMTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N4L0</accession>
    <name>A0A1C7N4L0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">aspartyl aminopeptidase</fullName>
            <ecNumber evidence="4">3.4.11.21</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">dapA</name>
        <name evidence="12" type="ORF">A0J61_07981</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Release of an N-terminal aspartate or glutamate from a peptide, with a preference for aspartate.</text>
            <dbReference type="EC" id="3.4.11.21"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3 11">Belongs to the peptidase M18 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.11.21" evidence="4"/>
    <dbReference type="EMBL" id="LUGH01000576">
        <property type="protein sequence ID" value="OBZ83968.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N4L0"/>
    <dbReference type="FunCoup" id="A0A1C7N4L0">
        <property type="interactions" value="376"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N4L0"/>
    <dbReference type="InParanoid" id="A0A1C7N4L0"/>
    <dbReference type="OrthoDB" id="9880441at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000324">
        <property type="term" value="C:fungal-type vacuole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004177">
        <property type="term" value="F:aminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008237">
        <property type="term" value="F:metallopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05658">
        <property type="entry name" value="M18_DAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.250.10:FF:000001">
        <property type="entry name" value="Aspartyl aminopeptidase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.250.10">
        <property type="entry name" value="Aminopeptidase i, Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.10">
        <property type="entry name" value="Zn peptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001948">
        <property type="entry name" value="Peptidase_M18"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023358">
        <property type="entry name" value="Peptidase_M18_dom2"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF002759">
        <property type="entry name" value="PRK02813.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28570">
        <property type="entry name" value="ASPARTYL AMINOPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28570:SF3">
        <property type="entry name" value="ASPARTYL AMINOPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02127">
        <property type="entry name" value="Peptidase_M18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00932">
        <property type="entry name" value="AMINO1PTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101821">
        <property type="entry name" value="Aminopeptidase/glucanase lid domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53187">
        <property type="entry name" value="Zn-dependent exopeptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 11 12" id="KW-0031">Aminopeptidase</keyword>
    <keyword evidence="8 11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7 11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10 11" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="6 11" id="KW-0645">Protease</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9 11" id="KW-0862">Zinc</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011965"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU004386"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="OBZ83968.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="472" mass="52028" checksum="78DD9D7BD52C3DBD" modified="2016-11-30" version="1">MSQKFMPTIPQEALDFVKFVNNSPSPFHATFEAAKLLKAAGFQEIKERDSWNNGTIKRQGKYYFTRNGSAIVAFEVGGKYNPGNGFSIVGAHTDSPCLKVKPISKKEKSGYLEVGVQLYGGGIWHTWFDRDLSVAGRVLVEQEDGTFKHTLVKVNRPILRIPTLAIHLDRTANDGFTFNKETQLAPILATAAKAQLSGVQATEGVESQAHHHPVLIQILADEMNVKPAQIHDFELAVYDTQPSTIGGACNEFIFSPRLDNLGMSYCSIRALAEAKHLDKDTNIRIAALFDNEEIGSQTAHGADSNLLPTTLQRLANTHVVDADAVSPTAFEESLLKSVLVSADMAHAIHPNYAEKHEENHRPEMHKGTVIKVNANQRYATTAITSLVLKQLAKKHQIPIQEFVVRNDSPCGSTIGPMLSAKLGLRTVDIGNPQLSMHSIRETGGTDDVKHGIDLLRVFYEEFAELEQKFIVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N527</accession>
    <name>A0A1C7N527_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Septin spn4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">spn4_2</name>
        <name evidence="6" type="ORF">A0J61_07842</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000555">
        <property type="protein sequence ID" value="OBZ84108.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N527"/>
    <dbReference type="FunCoup" id="A0A1C7N527">
        <property type="interactions" value="27"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N527"/>
    <dbReference type="InParanoid" id="A0A1C7N527"/>
    <dbReference type="OrthoDB" id="416553at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005938">
        <property type="term" value="C:cell cortex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032156">
        <property type="term" value="C:septin cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01850">
        <property type="entry name" value="CDC_Septin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000238">
        <property type="entry name" value="Cell division control 12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030379">
        <property type="entry name" value="G_SEPTIN_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016491">
        <property type="entry name" value="Septin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025662">
        <property type="entry name" value="Sigma_54_int_dom_ATP-bd_1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18884">
        <property type="entry name" value="SEPTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00735">
        <property type="entry name" value="Septin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006698">
        <property type="entry name" value="Septin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51719">
        <property type="entry name" value="G_SEPTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00675">
        <property type="entry name" value="SIGMA54_INTERACT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2 3" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Septin-type G" evidence="5">
        <location>
            <begin position="25"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="322"/>
            <end position="374"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU004560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51719"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OBZ84108.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="382" mass="43985" checksum="3353F57845FEF784" modified="2016-11-30" version="1">MSPSATSGVGVAHLPNQRHKIVSKRGANFTLMVCGESGVGKTTFVNTLFTTGIKAEKDLKKRHAKQIEKTVEIEITKAELEEKNFKVKLTIIDTPGFGDYVNNYNSWMPIYEFLDDQHESYMLQEQQPTRKGSIDMRVHACLYFIRPSGHSLKPLDIEVMKHLGSRVNLIPVIAKADTLTPKDLAQYKQNILDSIAANHIQVYSCPIDSEDEEVTEVNKSIMASMPFAIIGSTQDVTTADGRTVKGRQYSWGVAEVENEEHCDFKKLRKLLIRSHMHDLISTTEENHYENYRQAQMSTRKFGEPKSKKYENPKFKEDEDDLRLNFTKQVKEEENRFRQWEAQLVAERDRLNKDLEEQHAQIKALEAELEHMYQLHGRGTVRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N548</accession>
    <name>A0A1C7N548_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">H(+)-transporting two-sector ATPase</fullName>
            <ecNumber evidence="3">7.1.2.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="primary">atp2_0</name>
        <name evidence="15" type="ORF">A0J61_07694</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>ATP + H2O + 4 H(+)(in) = ADP + phosphate + 5 H(+)(out)</text>
            <dbReference type="Rhea" id="RHEA:57720"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="7.1.2.2"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ATPase alpha/beta chains family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="7.1.2.2" evidence="3"/>
    <dbReference type="EMBL" id="LUGH01000535">
        <property type="protein sequence ID" value="OBZ84255.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N548"/>
    <dbReference type="STRING" id="101091.A0A1C7N548"/>
    <dbReference type="InParanoid" id="A0A1C7N548"/>
    <dbReference type="OrthoDB" id="14523at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045259">
        <property type="term" value="C:proton-transporting ATP synthase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046933">
        <property type="term" value="F:proton-transporting ATP synthase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042776">
        <property type="term" value="P:proton motive force-driven mitochondrial ATP synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd18110">
        <property type="entry name" value="ATP-synt_F1_beta_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1140.10:FF:000001">
        <property type="entry name" value="ATP synthase subunit beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1140.10">
        <property type="entry name" value="Bovine Mitochondrial F1-atpase, Atp Synthase Beta Chain, Chain D, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055190">
        <property type="entry name" value="ATP-synt_VA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020003">
        <property type="entry name" value="ATPase_a/bsu_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050053">
        <property type="entry name" value="ATPase_alpha/beta_chains"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024034">
        <property type="entry name" value="ATPase_F1/V1_b/a_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15184">
        <property type="entry name" value="ATP SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15184:SF71">
        <property type="entry name" value="ATP SYNTHASE SUBUNIT BETA, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22919">
        <property type="entry name" value="ATP-synt_VA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47917">
        <property type="entry name" value="C-terminal domain of alpha and beta subunits of F1 ATP synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00152">
        <property type="entry name" value="ATPASE_ALPHA_BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-0066">ATP synthesis</keyword>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="11" id="KW-0139">CF(1)</keyword>
    <keyword evidence="6" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="9" id="KW-0406">Ion transport</keyword>
    <keyword evidence="10" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-1278">Translocase</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ATP synthase A/B type C-terminal" evidence="14">
        <location>
            <begin position="42"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="15">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023196"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023310"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00048383"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF22919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="OBZ84255.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="161" mass="17979" checksum="0AB06731E378431D" modified="2016-11-30" version="1" fragment="single">PAPATTFAHLDATTVLSRSIAELGIYPAVDPLDSKSRILDPRIVGEEHYKVATEVQQILQNYKSLQDIIAILGMDELSEEDKLVVERARKIQRFLSQPFAVAQVFTGYEGRLVKLTDTIRSFQEILGGKHDSLPESAFYMQGDISDVQKRAEEIAKEMGSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N549</accession>
    <name>A0A1C7N549_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_07726</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000539">
        <property type="protein sequence ID" value="OBZ84220.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N549"/>
    <dbReference type="STRING" id="101091.A0A1C7N549"/>
    <dbReference type="InParanoid" id="A0A1C7N549"/>
    <dbReference type="OrthoDB" id="2020070at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="entry name" value="Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33604">
        <property type="entry name" value="OSJNBA0004B13.7 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33604:SF3">
        <property type="entry name" value="OSJNBA0004B13.7 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ84220.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="517" mass="60129" checksum="4411C03D795AB017" modified="2016-11-30" version="1" fragment="single">AAGIPSIVLPTDPIERAYWGDVRLKSKHSQITSTCQQANQTKLEISHQPSVLFYLDSLKALNDLKPLICQFNQLSTIDVHLITHQPNVTVDCHKSVWIHPVDLLYRHPDWQQFEQLPMRWKHLFTSIQPHLIIHTSPMMRAMQTITNVTSIYLPSQEIQHALWMTDLSLDTLTKWHQIDIKLIVTTDKKPHALSRLLTSASEAYYLGDSVDLSLLLDVSSDRLTHTFAHRFSWSHGQKSMRHRIAHSSKASLFVESWYPSHRHEYAILLHQDLELSPLFYSWAKYSVLKYRYQSDHPDLFGISLYAPRLIETDPSGRHLFHQRPSSDYLMQWPSYLGALYFPDHWREFHDYITARQADTWGMAMQSVVVPNLRSNDWVKSWRRYFEELVYLRGYVMLYPQTSYATVHMELKKKFMTHFGDALSLYQVPLANTTHSLLNVDQLPLFDIWGHPIDQKTLKDRGLALQNQVSACLPSIAPEDKFDPTDLLCPFGRIVSVELENEDDPIPSLLPKEIHVYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N5B9</accession>
    <name>A0A1C7N5B9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">50S ribosomal protein L24</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">rplX</name>
        <name evidence="5" type="ORF">A0J61_07650</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uL24 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000529">
        <property type="protein sequence ID" value="OBZ84300.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N5B9"/>
    <dbReference type="FunCoup" id="A0A1C7N5B9">
        <property type="interactions" value="349"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N5B9"/>
    <dbReference type="InParanoid" id="A0A1C7N5B9"/>
    <dbReference type="OrthoDB" id="359154at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06089">
        <property type="entry name" value="KOW_RPL26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01326_B">
        <property type="entry name" value="Ribosomal_uL24_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005824">
        <property type="entry name" value="KOW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014722">
        <property type="entry name" value="Rib_uL2_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003256">
        <property type="entry name" value="Ribosomal_uL24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057264">
        <property type="entry name" value="Ribosomal_uL24_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041988">
        <property type="entry name" value="Ribosomal_uL24_KOW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008991">
        <property type="entry name" value="Translation_prot_SH3-like_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01079">
        <property type="entry name" value="rplX_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12903">
        <property type="entry name" value="MITOCHONDRIAL RIBOSOMAL PROTEIN L24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00467">
        <property type="entry name" value="KOW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17136">
        <property type="entry name" value="ribosomal_L24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00739">
        <property type="entry name" value="KOW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50104">
        <property type="entry name" value="Translation proteins SH3-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 5" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="KOW" evidence="4">
        <location>
            <begin position="30"/>
            <end position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00739"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OBZ84300.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="195" mass="22089" checksum="5C6DD1DA83BCAC8C" modified="2016-11-30" version="1">MHRFKAQGVSTRVFPKPQWVNPKDRVTTWNIVTGDKVAIIAGKDKDTIGEIKSVDRKTNTVIVEGKKLAKKHVPMQPGAPEGIIRKELPIHYSNVMLLHPDTQMPTRIDRRKVTKTLEDGRVVSRWTRFVKGTGIEIPKPLRKYNDQSGEEHFTTSPEDATLVTYTSDLSQPPFPQELVGELRNIYKKKPVVPSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N693</accession>
    <name>A0A1C7N693_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Arsenate reductase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">A0J61_07410</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Putative mitochondrial redox protein which could be involved in the reduction of small toxic molecules.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the FMP46 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000499">
        <property type="protein sequence ID" value="OBZ84538.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N693"/>
    <dbReference type="InParanoid" id="A0A1C7N693"/>
    <dbReference type="OrthoDB" id="59229at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006660">
        <property type="entry name" value="Arsenate_reductase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012882">
        <property type="entry name" value="Fmp46"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28071">
        <property type="entry name" value="REDOX PROTEIN FMP46, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28071:SF1">
        <property type="entry name" value="REDOX PROTEIN FMP46, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07955">
        <property type="entry name" value="DUF1687"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51353">
        <property type="entry name" value="ARSC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0809">Transit peptide</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002963"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009734"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OBZ84538.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="127" mass="14282" checksum="F171F717826DA7DD" modified="2016-11-30" version="1">MSFRPPRSLPILTLFHNYQSEKSKAALALLQSKQKNARGDDVYRIDIIGQNEAPTDTQLNQVASFLGSPNAWKDMVQEQEVESVQDALHVIQANPGLLRRPIVVDWEKGKAAMGSRTIEQLIQERSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N724</accession>
    <name>A0A1C7N724_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Uncharacterized protein C1F3.03</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">SPAC1F3.03</name>
        <name evidence="9" type="ORF">A0J61_06989</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the WD repeat L(2)GL family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000450">
        <property type="protein sequence ID" value="OBZ84955.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N724"/>
    <dbReference type="STRING" id="101091.A0A1C7N724"/>
    <dbReference type="InParanoid" id="A0A1C7N724"/>
    <dbReference type="OrthoDB" id="19944at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045159">
        <property type="term" value="F:myosin II binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019905">
        <property type="term" value="F:syntaxin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006887">
        <property type="term" value="P:exocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006893">
        <property type="term" value="P:Golgi to plasma membrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd15873">
        <property type="entry name" value="R-SNARE_STXBP5_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013905">
        <property type="entry name" value="Lgl_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042855">
        <property type="entry name" value="V_SNARE_CC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10241">
        <property type="entry name" value="LETHAL 2 GIANT LARVAE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10241:SF25">
        <property type="entry name" value="TOMOSYN, ISOFORM C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08596">
        <property type="entry name" value="Lgl_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50892">
        <property type="entry name" value="V_SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3" id="KW-0268">Exocytosis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="249"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="domain" description="V-SNARE coiled-coil homology" evidence="8">
        <location>
            <begin position="1118"/>
            <end position="1182"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="566"/>
            <end position="632"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="700"/>
            <end position="727"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="836"/>
            <end position="871"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1120"/>
            <end position="1153"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="623"/>
            <end position="632"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="856"/>
            <end position="871"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="1139"/>
            <end position="1153"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008070"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OBZ84955.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="1183" mass="131917" checksum="70BF9F10B4BD0DDC" modified="2016-11-30" version="1">MSLFDKISGLASKAKENVVSKTFLSKDRRLEQTLSQHIDRNDIYFEKVSTYGMPSTVGVVAFDCVAGLLAVAGDSNRSYVKVFGKGISATIDIPNSEGIKYMQFRTGYPILILIDKSNTLITVDLRTKSIRHTLKAHEIITCQAYCEGTDWLFVGYANGFVDVFDIMQGLFAPYQIPDLLDTESPENQQNDHLEKHVVVDLQLHPTELNTLLVGYDSAVFLWNIKEATIRRTFSLRRLDRSSPYRTANLTCLVWSPNGTRFMAGYDDGCVHLWDIKHEHKPIASRRLSETFLHVSEDPSQPAEPVYQMAWYLNTAYNRSYLVVAGGLNPTDIQGLNVLEFDLNCELREPKKQTIMPLPTDLSHFVVMNKDPYHMRMVDPFAIAIIGSDHCLRVLSLDHGFPSLQLPPALEFLSPFILSACHIPHVSENVFQKLTVIDTKHSIHYVPLTGGVAGPDHIYRIESNDLLITIHQGEVIKFWDASFTALRPLVDLSIHCLTDLEDSSAFLCCLDVNRETGMLSVGFSNGSILIYNHHSPVQEPPVPGSKNQEFINNCDDTLKEISDLLDDMNSEPDTENHEPVSAPTGDIEQPNMMMNPFESVQTNEKELPDVPTTQSSKVPEPLPKTTSHSSKFRNISKANKDSFGYFASLSINLGKSPITSMMSVNSSILVTASEDGKFYVLDIQEQSVLFWLNISQMDYQNHAPSQTNPPKHEAQPNTPEPPKVPQKEPASITSLYHFDTYKASKGKKKSLVLITVFSVFVNQPLKPLVMEISTQIFVGLSNGHIYQFDLFCLIDRGMSLLTSCDKLNDYKVLHLHSGLQNMSAVDLSGSLLSSSTEAKHEIPTKDSTGSVLDDSSKLGSTQEGQPLTKKSSYHSITTVSTASIASDPVEGNANISRANSNASANSNSSGAIASKRMLAIGKGEYRQQENPHFLLCVTQTGISIVLSGYNVKLFSRDFPKDVKPIRSEVVKSKGSVCLVVLLDTGKLVFYSLPTLEVIAETNLPDTCELKRLSESSLSTDGRIIFWTGKYEMKQYSFVHKPHLALGESVILFDSHIVPPPHPSTLVQQQKPKKSWFDAVAGAFQKEALTVTELDLLMGRVPMEDPNEVRKQKVEAYKAKMQNESNSSKGPGGVFSQLGEKMNERGEKLNEMEQKFSELNSASGDFLKAVREYNERQARKKWWEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N733</accession>
    <name>A0A1C7N733_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">E3 ubiquitin-protein ligase</fullName>
            <ecNumber evidence="10">2.3.2.27</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">ubr1</name>
        <name evidence="13" type="ORF">A0J61_06985</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N-terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 15">
            <text>S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.</text>
            <dbReference type="EC" id="2.3.2.27"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 10">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="similarity">
        <text evidence="8 10">Belongs to the E3 ubiquitin-protein ligase UBR1-like family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.27" evidence="10"/>
    <dbReference type="EMBL" id="LUGH01000449">
        <property type="protein sequence ID" value="OBZ84965.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="FunCoup" id="A0A1C7N733">
        <property type="interactions" value="398"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N733"/>
    <dbReference type="InParanoid" id="A0A1C7N733"/>
    <dbReference type="OrthoDB" id="26387at2759"/>
    <dbReference type="UniPathway" id="UPA00143"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000151">
        <property type="term" value="C:ubiquitin ligase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016567">
        <property type="term" value="P:protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071596">
        <property type="term" value="P:ubiquitin-dependent protein catabolic process via the N-end rule pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd16482">
        <property type="entry name" value="RING-H2_UBR1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd19673">
        <property type="entry name" value="UBR-box_UBR3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.10.110.30:FF:000001">
        <property type="entry name" value="E3 ubiquitin-protein ligase UBR2 isoform 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.110.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1390.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.2670">
        <property type="entry name" value="E3 ubiquitin-protein ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003769">
        <property type="entry name" value="ClpS_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042065">
        <property type="entry name" value="E3_ELL-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044046">
        <property type="entry name" value="E3_ligase_UBR-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014719">
        <property type="entry name" value="Ribosomal_bL12_C/ClpS-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039164">
        <property type="entry name" value="UBR1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055194">
        <property type="entry name" value="UBR1-like_WH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003126">
        <property type="entry name" value="Znf_UBR"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21497:SF24">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE UBR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21497">
        <property type="entry name" value="UBIQUITIN LIGASE E3 ALPHA-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02617">
        <property type="entry name" value="ClpS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18995">
        <property type="entry name" value="PRT6_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22960">
        <property type="entry name" value="WHD_UBR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02207">
        <property type="entry name" value="zf-UBR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00396">
        <property type="entry name" value="ZnF_UBR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54736">
        <property type="entry name" value="ClpS-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51157">
        <property type="entry name" value="ZF_UBR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 10" id="KW-0808">Transferase</keyword>
    <keyword evidence="6 10" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="7 10" id="KW-0862">Zinc</keyword>
    <keyword evidence="5 10" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="UBR-type" evidence="12">
        <location>
            <begin position="117"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="UBR-type" evidence="9">
        <location>
            <begin position="117"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="272"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="448"/>
            <end position="490"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1662"/>
            <end position="1682"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="276"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="468"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="479"/>
            <end position="490"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="1670"/>
            <end position="1680"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00046341"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00508"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU366018"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="OBZ84965.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="2249" mass="256146" checksum="5220D582402D4ECE" modified="2016-11-30" version="1">MTSEKANFSSSYKLNLDTNQSNSQLSDFLWQSPSQFNCHFDESAKQAILTRCYEALWMSNDDLMKQYFFGSKEQMQHVLLLQSQRHDGKEQNTVIDPTLWHTNAIIPTQDLSSQKGRQCGHVFRKGEPVYRCRNCGLDDTCVFCSKCFHATDHDGHDILFSVSPGSGGCCDCGDPEAWKVPLQCKIHSSEHTYTKLDIGSERASIDPALIDSIRATMASVLNFLLDTFALAPDEVVLNSSTEELIRENQEQRTILNRMGIPNQTGLVNTATSTRLEEEDDVDMDKENDDARQDTLHSNPSIPIKEGEKELYACIAWNDEAHAFSHVLESLMTATGWEWQKAKQIVDVIHVHGREIIAVSEDIAELRKIAAPLSAINLGVTIRPAKDTFREQVCGLLVDWLNEIINGRTRFFSDVPNGDAIVRNILCEELCAGWELRLPLALLTTGSRTSNSDKNLAAKTKQTKSEGAEEKEDEEEEGPVEVREDNMRDDTVISDSLEDVEMFEPEDTQSKQNSSVAYRNQCDVASIDWDPAAMVREYQQLRAEEIEFGEHLSDRLGKKPSRDNDHMYQERTKLATHLQKEFEQKLRLDYFMLYDLKLWKEVRISLRELYIASLASNPHFKKILGKRLARNYARLAESFLLRDREPENSIILFSVQLLTVPTVSDLLVHHYYFFGLICSTLTAFFLTDRLYLLLPSQRLDYPSRINCESRAFRTRRYFNAFHDLRYIMNVDMIKCVLAQDPLYLRQYLDLISLFQGMNAQICQKDTHVEYESEIWVNAFNVTLQIAKCCRQFSDCFSMLPLNTEREKTSTVSTIVRAVSRVLKAIVEWGQIDEEEEEMEKNRQLAQPNNPTGNNVPSQKIYGAMAQEFHTVSLGYTEPFEVIKYNVATQPVSFHHPLHWLLSGLLEYAHLLTDDVLLQAGWEGGFKKVITLFHHSSATSASVLLSILDFPIRTIVFSSQIRAGVWVRNGYGIRNQAHHYRDISLRENTYDADVFLLQLGFAILDSNRFLATLLDRFDLTSWFLGTKKHETYDHSQTVFMVEELLNLMIVISCERANVSGMSIHEKIRREIIHSLCLGSSAYSELTKHIPERIAEHPEFDHILNQVAHFKSPDGVNDHGTYELKDEYFEHVDTYFWHFSRNNREEAESIFKSRWKKRNSNRKEEEFFILPKISPIASGPFENMNSFLQSSLFVQMLSFALWNIYTGENHKSDTILDQVLYLILLALTDENSEDAHQSGLGKFYDYVCSLHFTVETPNSSEESKSTAVPSQAQNMSLFDIMVVLYRDERYGEISSRLQWIFEKLLMKGSATTQQQVQAWQLQHQEEMQNNSQQDTLTELSETERKKLAAKERQLKIMAQFAQAQSQFMEQNEFLYEDEDDAFEDAPEAFSSSENEKDSKAGVVHRFCSYPTGTCIVCQEDVNDRSLPYGLLGLIQTSNIVRETPMNDTLLINDIYKMGANLDTDWDDHQCLDESVSTVPGFPAHLHKTGLYASSCGHLMHIKCFEVYCNSIDSRHAAQLTRNHPENRSRKEFMCPLCKSLGNILLPVFWKGKKESYPGVLSKAEEANYAFFYKSEVNQVVAKLKSSIINSSRNAQIRKSSRDTSATSRMKDVMTQLLPNLPTIVTAATATGTPPPITPPFANAREWAPTTFPTRLPVAIPFEANTTQNTELQPPHDEENREGGDQMNIEEDELTRDSDSMLVRNTYPADSLPLPDGHLGPFENDVLHSTAMVSALLIKKSYHRLLDVLGLIYQEICTDENQRDMSTAAENVDMLWGIMGYTIAGVEIAARGSARTSFQAEENTTYTLFDQIPAQTQTLLRILSDTVMAYTTLMCSSGADPKFSSTSSLPMARVSMFCLGRMRQIFEVNVDDVANLPAGPSQKIVLYDNAPLLEDDPFMILTELSLHLVPMTQADIFPFLRTLLLAELAKTAVGLLQDRLGRQESEREKQEIRSSLPSEPSHDIAAAKAFAFSLMDKLQFTPEEAQVAFRKFGNDTCFCALLKFFALPFLRRALILMIARFGLVIPCIENDNSTDELDRLMRLLHLPKFTELLQPTLMTESLLQYWCSQHLRESERRIQVQEGLMAPLSSSRLNNIPLDLPTPFQLIALPKRLDLLFDESMKRVCQKCGTVPSDPAICLFCGTFVCSQSFCCAEDEEGECNLHTLECGGEIGVFLSIKRCVLILLHNGNGWFMNAPYLDPHGEVDQGLRHGRPQYLNAKRYAEIRKLWLQHNIPIYVARQIEANYDIGGWTTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N7X5</accession>
    <name>A0A1C7N7X5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Transmembrane 9 superfamily member</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">TMN6</name>
        <name evidence="8" type="ORF">A0J61_06742</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the nonaspanin (TM9SF) (TC 9.A.2) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000422">
        <property type="protein sequence ID" value="OBZ85202.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N7X5"/>
    <dbReference type="FunCoup" id="A0A1C7N7X5">
        <property type="interactions" value="496"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N7X5"/>
    <dbReference type="InParanoid" id="A0A1C7N7X5"/>
    <dbReference type="OrthoDB" id="1666796at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072657">
        <property type="term" value="P:protein localization to membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007034">
        <property type="term" value="P:vacuolar transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004240">
        <property type="entry name" value="EMP70"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10766:SF111">
        <property type="entry name" value="TRANSMEMBRANE 9 SUPERFAMILY MEMBER 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10766">
        <property type="entry name" value="TRANSMEMBRANE 9 SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02990">
        <property type="entry name" value="EMP70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0732">Signal</keyword>
    <keyword evidence="3 7 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008810984" description="Transmembrane 9 superfamily member" evidence="7">
        <location>
            <begin position="20"/>
            <end position="619"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="257"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="320"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="353"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="390"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="426"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="472"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="511"/>
            <end position="536"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="548"/>
            <end position="568"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="588"/>
            <end position="609"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005227"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU363079"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OBZ85202.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="619" mass="69797" checksum="0A2745EB5F79C7AD" modified="2016-11-30" version="1">MQLKTLLLSSLATLSVSHAFYLPGVAPHDYTKGELVKLNVNALTPSSNQQVKSVISYDFYNEQFHFCKPRKGEQEQSESIGSVLFGDRIFNSAFELRMQEPQECKLLCEVDDIPAQDAQFINERIKEGYAFNWAVDGLPAATEDIDVHTNEKYYNIGFKMGSVEGETAFLNNHYDIKIHYHTTSRGLSRVVGVSVDPYSRNTPSSHRCSDGLDKFHLSEDGKGRVVYTYSVQWIPSDTVWATRWDGYLHVLDPSIHWFSLINSIVIVLFLTGMVSMILLRALHKDISRYNAVDAQEDVQEDYGWKLVHGDVFRPPQHPMLLSVLTSSGVQLIAMTGLTLVFAVFGFLSPSNRGSLATMMILFFMIFSCFSGYASARLYKMFGGESWKTNMLLTATVLPGTLVGGLVGLNFFLIYSDASGAVPFGTMLGLAALWIVISFPLSIAGSYIGLRKPRIEQPVRTNQIPRQIPDQPLYLRAVPSILMGGILPFGAIFIEIFFIFNSIWFHRIYYGIGFLFMVFAVLILTCSQVAILMCYFHMCNEDYHWSWRAFMTAGATGFYVYVYSFLYYYTKLNINTFASTVLYFGYSSIISILLSIMTGSIGYLSCLVFLRKIFSSIKVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N8C6</accession>
    <name>A0A1C7N8C6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Eukaryotic translation initiation factor 2 subunit alpha</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">tif211</name>
        <name evidence="10" type="ORF">A0J61_06617</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytosol</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the eIF-2-alpha family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000408">
        <property type="protein sequence ID" value="OBZ85331.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N8C6"/>
    <dbReference type="FunCoup" id="A0A1C7N8C6">
        <property type="interactions" value="798"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N8C6"/>
    <dbReference type="InParanoid" id="A0A1C7N8C6"/>
    <dbReference type="OrthoDB" id="1685042at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033290">
        <property type="term" value="C:eukaryotic 48S preinitiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005850">
        <property type="term" value="C:eukaryotic translation initiation factor 2 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043614">
        <property type="term" value="C:multi-eIF complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990856">
        <property type="term" value="F:methionyl-initiator methionine tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043022">
        <property type="term" value="F:ribosome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001731">
        <property type="term" value="P:formation of translation preinitiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd04452">
        <property type="entry name" value="S1_IF2_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.140:FF:000015">
        <property type="entry name" value="Eukaryotic translation initiation factor 2 subunit alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.150.190:FF:000002">
        <property type="entry name" value="Translation initiation factor 2, alpha subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1130">
        <property type="entry name" value="EIF_2_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.190">
        <property type="entry name" value="Translation initiation factor 2, subunit 1, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003029">
        <property type="entry name" value="S1_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044126">
        <property type="entry name" value="S1_IF2_alpha"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024055">
        <property type="entry name" value="TIF2_asu_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024054">
        <property type="entry name" value="TIF2_asu_middle_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011488">
        <property type="entry name" value="TIF_2_asu"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10602">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 2 SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10602:SF0">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 2 SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07541">
        <property type="entry name" value="EIF_2_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00575">
        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00316">
        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110993">
        <property type="entry name" value="eIF-2-alpha, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF116742">
        <property type="entry name" value="eIF2alpha middle domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50126">
        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 10" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="5" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="7" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="S1 motif" evidence="9">
        <location>
            <begin position="19"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="293"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="297"/>
            <end position="313"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004514"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007223"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OBZ85331.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="313" mass="35575" checksum="CB5D658761BE3044" modified="2016-11-30" version="1">MADNKFFCRMYENEFPKVDDVVMVNVRQIADMGAYVKLLEYGDREGMILLSELSRRRIRSVQKLIRVGRDEVVVVLRVDEEKGYIDLSKRRVTPEDIIKCEEKYNKSKTVHSILRHVAEKNDVPLQDLYETIGWPLYKKFGHAYDAFKVAILDADTVFQGMDIPAEVMKELLFIIKRRMTPHPVKIRAQLDIRCTGIDGVNAIRAALKAGESVGSEDIPVKITYLAAPFYVVTVDSLDKKLGFEIIEKSIEAIKTELDKFAWTKFKVEKEAKLVSDSDDRDFAALLAKAEKENELVSGDEDEGDAVAASDDDM</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N976</accession>
    <name>A0A1C7N976_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_06771</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000425">
        <property type="protein sequence ID" value="OBZ85179.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N976"/>
    <dbReference type="STRING" id="101091.A0A1C7N976"/>
    <dbReference type="InParanoid" id="A0A1C7N976"/>
    <dbReference type="OrthoDB" id="1394818at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019487">
        <property type="entry name" value="RAM_signalling_pathway_SOG2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10428">
        <property type="entry name" value="SOG2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="371"/>
            <end position="393"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ85179.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="393" mass="44058" checksum="0A99843FE0FB4A7E" modified="2016-11-30" version="1">MKQTTNPLSLTRIDSEAIENEAPTYLQKTNTQRSMETTSKSVIEASQTILFTASTLQRTITRCINCIGNDSLHAAFSPILQKSKLSTEKLLSLLDLVEKRPELCQDLIQITKHCILILKELCWTLRTRLSTVVQGLDAKFSRNLLMNLYSATVDMKDAWLVIQPFLSVDSSTTLLSFKSMSRQLSQSETQSLQSPSQSLADADHQLYTHLRSAISNSLHVLTTLRQSIDETLQTPIASSLKEKLTELSRQAQYTIELSHQLDKSIEANMASSKEESLLALPPNECLRQIWGDTSIHLKAIVNVMTFIRSISKEEEFSWPKSIKQGCLYMTRMTAEVAKLWNSHSTFAENGLFLGRYERSSSVSSVDQYASSPAATATTHTAPNDIPIQHRAKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N9D1</accession>
    <name>A0A1C7N9D1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">GPALPP motifs-containing protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">GPALPP1</name>
        <name evidence="3" type="ORF">A0J61_06411</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000386">
        <property type="protein sequence ID" value="OBZ85538.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N9D1"/>
    <dbReference type="STRING" id="101091.A0A1C7N9D1"/>
    <dbReference type="InParanoid" id="A0A1C7N9D1"/>
    <dbReference type="OrthoDB" id="73491at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022226">
        <property type="entry name" value="DUF3752"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046331">
        <property type="entry name" value="GPAM1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46370">
        <property type="entry name" value="GPALPP MOTIFS-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46370:SF1">
        <property type="entry name" value="GPALPP MOTIFS-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12572">
        <property type="entry name" value="DUF3752"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF3752" evidence="2">
        <location>
            <begin position="222"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="25"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="93"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="231"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="121"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="192"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="258"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="328"/>
            <end position="339"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12572"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ85538.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="373" mass="42541" checksum="53EC68CED8B22E8B" modified="2016-11-30" version="1">MIGPAIPEELLKNKRQNQAEIDIALSDDESDTLGPQLPPQDVTVGPAIPADILVQRRQREEGSAIGPQIPDHIKQQKINSDEIAISDDDAEEVVTGPAMPPHILEKMNKNAQPEEEEVDAADFAPALPPDLLAERHQQQTESHGRRRRRPAGPSFPMGSMPSVEDDDDLVGPSLPQNYNPEEESKYSAIQAIEERARQSRESMENKDKKDTKIERPEWMLAPPEVDYLKAAHSGKSRQFSNRNMTEEERDNTAWIETPADRERRLHEEQKSGGKRKAYDQQPTISKEEMQVRQNVHEYNIQTRPMTLLEMHQQGRKKRSKQVTDEEDVSKRPFDREKDLLSGGRKLDRKQKKEIFKNSSELGSKFGYGRSSFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N9I7</accession>
    <name>A0A1C7N9I7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_06224</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000366">
        <property type="protein sequence ID" value="OBZ85730.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N9I7"/>
    <dbReference type="InParanoid" id="A0A1C7N9I7"/>
    <dbReference type="OrthoDB" id="2218040at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12937">
        <property type="entry name" value="F-box-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="1">
        <location>
            <begin position="2"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ85730.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="601" mass="69567" checksum="A49AD72F422028C5" modified="2016-11-30" version="1">MRSTWHDLPTELLHYIYSKLDNEDITTCLCVCPQWQRVALAQLYRNVTIKNKKQLEKFVHTISTSTYCPGQYITDLYVAGDFRDELQHPVFSEDGEPLDKFSQIVKYAPHLEAFSLGRLSTLFWQRMAAETSQGKLSQINFFQHPNWEKEFDSYHKVILNLSKTMTDIAIYDTRAMDQYDCEVLFHKLPEFERLLFLTLKWKTRMSLAVLDRTIDALPKLHVLTLKVDSAEEPSTFDHDQSLTLKPHQTLSKLTLSALLNSEDVFLYIMEKFPQLIDLDVSALEDLPLSPRPPVFSNDTMDRLTDYLSKLREFSFKNIQFENIYDLIDRVLDPTNDIAVDLWLYQPDQFFKNVCVLITRHQKDQASELNFEIQNTTYPIFLQRLGGKLHSLNIDCATESEVFITAGRDLVLSPEVVRFDFGDIISTCAQVKTVTVNDGIFFDVDSEGPQNNSITSMVFKTCECTDGFLANLSVRLPRLNRIEFKHVILCYSENNLQEEHSSHVMRFHMPQTSFHVFAIKDSNLIENSDYLYLKIILSSGERHYKLSEREASLVTPEEYSSVQGINNPVLSIEIACRSIEQIQLYDSTRHAQINHTLQDIVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N9K6</accession>
    <name>A0A1C7N9K6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Protein EI24</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">A0J61_06157</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000358">
        <property type="protein sequence ID" value="OBZ85795.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N9K6"/>
    <dbReference type="InParanoid" id="A0A1C7N9K6"/>
    <dbReference type="OrthoDB" id="266518at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016236">
        <property type="term" value="P:macroautophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059112">
        <property type="entry name" value="CysZ/EI24"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21389:SF0">
        <property type="entry name" value="ETOPOSIDE-INDUCED PROTEIN 2.4 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21389">
        <property type="entry name" value="P53 INDUCED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07264">
        <property type="entry name" value="EI24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="42"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="75"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="113"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="137"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="176"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="201"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="236"/>
            <end position="257"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OBZ85795.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="262" mass="30644" checksum="285FC718267DCD0F" modified="2016-11-30" version="1">MNNLSSHAHCFNQGVKDAFQWQRVFKLVTTSRTVQHTLLKSLALNGIVYLGLLVFLETFYNSPDHHLYGYSYTDLTGYPLYLICLLVNSRLYHRIAQYHLRADDVDRQNDSFTLVYTIVLYSNFAMLIALMRMVPFVGTPLSFLFYCIVMAYYCFEYKWAHQDWNIEQRMMYTEQHWAYCLGFGLPGTALTFFLSTLRAGGVFAIVYPFYIMMASSATPLAPFVRENSFVFLPYRMRVFACIRWMNMAILYVIRTLLGSRDT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NA09</accession>
    <name>A0A1C7NA09_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">40S ribosomal protein S12</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">RPS12_1</name>
        <name evidence="6" type="ORF">A0J61_06444</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the eukaryotic ribosomal protein eS12 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000389">
        <property type="protein sequence ID" value="OBZ85509.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NA09"/>
    <dbReference type="FunCoup" id="A0A1C7NA09">
        <property type="interactions" value="542"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NA09"/>
    <dbReference type="InParanoid" id="A0A1C7NA09"/>
    <dbReference type="OrthoDB" id="10249311at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022626">
        <property type="term" value="C:cytosolic ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015935">
        <property type="term" value="C:small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1330.30:FF:000005">
        <property type="entry name" value="40S ribosomal protein S12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029064">
        <property type="entry name" value="Ribosomal_eL30-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004038">
        <property type="entry name" value="Ribosomal_eL8/eL30/eS12/Gad45"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000530">
        <property type="entry name" value="Ribosomal_eS12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047860">
        <property type="entry name" value="Ribosomal_eS12_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11843">
        <property type="entry name" value="40S RIBOSOMAL PROTEIN S12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01248">
        <property type="entry name" value="Ribosomal_L7Ae"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00972">
        <property type="entry name" value="RIBSOMALS12E"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55315">
        <property type="entry name" value="L30e-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01189">
        <property type="entry name" value="RIBOSOMAL_S12E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 6" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Ribosomal protein eL8/eL30/eS12/Gadd45" evidence="5">
        <location>
            <begin position="27"/>
            <end position="121"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OBZ85509.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="142" mass="15690" checksum="9214540774003424" modified="2016-11-30" version="1">MSDHEEVINEVEVAVESTTTGQMSVEDALQEVLRRALVHDGLARGLKEAVKALDRRQAHLAVLVETCTESEYIKLVEALCSEHNINLIKVSDAKKLGEWAGLCKIDREGNARKVVGCSCVAVTDFGEESEAMNVLLDYFKTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NAA9</accession>
    <name>A0A1C7NAA9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Peptide-methionine (R)-S-oxide reductase</fullName>
            <ecNumber evidence="5">1.8.4.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">MSRB5</name>
        <name evidence="7" type="ORF">A0J61_07648</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>L-methionyl-[protein] + [thioredoxin]-disulfide + H2O = L-methionyl-(R)-S-oxide-[protein] + [thioredoxin]-dithiol</text>
            <dbReference type="Rhea" id="RHEA:24164"/>
            <dbReference type="Rhea" id="RHEA-COMP:10698"/>
            <dbReference type="Rhea" id="RHEA-COMP:10700"/>
            <dbReference type="Rhea" id="RHEA-COMP:12313"/>
            <dbReference type="Rhea" id="RHEA-COMP:12314"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:16044"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:45764"/>
            <dbReference type="ChEBI" id="CHEBI:50058"/>
            <dbReference type="EC" id="1.8.4.12"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="5">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the MsrB Met sulfoxide reductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.8.4.12" evidence="5"/>
    <dbReference type="EMBL" id="LUGH01000529">
        <property type="protein sequence ID" value="OBZ84294.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NAA9"/>
    <dbReference type="FunCoup" id="A0A1C7NAA9">
        <property type="interactions" value="74"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NAA9"/>
    <dbReference type="InParanoid" id="A0A1C7NAA9"/>
    <dbReference type="OrthoDB" id="44061at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033743">
        <property type="term" value="F:peptide-methionine (R)-S-oxide reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030091">
        <property type="term" value="P:protein repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006979">
        <property type="term" value="P:response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="2.170.150.20:FF:000009">
        <property type="entry name" value="Peptide-methionine (R)-S-oxide reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.150.20">
        <property type="entry name" value="Peptide methionine sulfoxide reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028427">
        <property type="entry name" value="Met_Sox_Rdtase_MsrB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002579">
        <property type="entry name" value="Met_Sox_Rdtase_MsrB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011057">
        <property type="entry name" value="Mss4-like_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00357">
        <property type="entry name" value="peptide-methionine (R)-S-oxide reductase MsrB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46081">
        <property type="entry name" value="PEPTIDE METHIONINE SULFOXIDE REDUCTASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46081:SF8">
        <property type="entry name" value="PEPTIDE METHIONINE SULFOXIDE REDUCTASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01641">
        <property type="entry name" value="SelR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51316">
        <property type="entry name" value="Mss4-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51790">
        <property type="entry name" value="MSRB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="MsrB" evidence="6">
        <location>
            <begin position="41"/>
            <end position="163"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007174"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU365044"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OBZ84294.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="163" mass="18554" checksum="B0DDB04D8732CCEB" modified="2016-11-30" version="1">MSFRLFSRQLSNSYKFSQRHFLYNPSIQTIRLSRTMTTKTEQEWRAVLSPEQFRVLRQKGTEAPGVGQYNKFYQKGVYHCAGCDAPLYVSDTKFDSGCGWPAFFEGIPGAITRHEDVTHGMVRTEICCAKCGGHLGHVFKGEGFKTPTDERHCVNSISLKFKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NAC9</accession>
    <name>A0A1C7NAC9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_05955</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000338">
        <property type="protein sequence ID" value="OBZ86001.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NAC9"/>
    <dbReference type="STRING" id="101091.A0A1C7NAC9"/>
    <dbReference type="InParanoid" id="A0A1C7NAC9"/>
    <dbReference type="OrthoDB" id="5594955at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16861">
        <property type="entry name" value="GLYCOPROTEIN 38"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16861:SF4">
        <property type="entry name" value="SH3 DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_1G13610)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="160"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="119"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="265"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="328"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="120"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="140"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="351"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ86001.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="365" mass="40129" checksum="D4190E365980342B" modified="2016-11-30" version="1" fragment="single">ICYALAIASRVCGGQDNTVAICSPNSNSDKLDLYLLYHPNDSEWQPVLKWSGLDKSKGVLVTHVNDSWYPAPLASNTSNVTWTMQLYLTGSDYDYQSDLDLIPSSHNYFPVPRPFTLIQSSSETPSTSTTVTSSKATDSPTNTLTAESSSNSPTNKLPGWAIAVICIAALLFIAAVAALIWAYRRYKQRKNRKSMVAVGLAHRSQKEREGDDEKVPVLTPSKNESNVAISNVMAPANSNANHTATAVGAGLLAANASMHSSTHHLVSPRSISPRHHDEASSFVTVSEKPPLGTHHEAHHSSSILSSTDALMIADTFRQFMRKPEWNEEMELNAQRQQIEEKGESGEEIEHEETLRDNLSNRKERT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NAL4</accession>
    <name>A0A1C7NAL4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Homeobox domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">A0J61_05946</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3 4">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000337">
        <property type="protein sequence ID" value="OBZ86008.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NAL4"/>
    <dbReference type="STRING" id="101091.A0A1C7NAL4"/>
    <dbReference type="InParanoid" id="A0A1C7NAL4"/>
    <dbReference type="OrthoDB" id="6159439at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030154">
        <property type="term" value="P:cell differentiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00086">
        <property type="entry name" value="homeodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001356">
        <property type="entry name" value="HD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051000">
        <property type="entry name" value="Homeobox_DNA-bind_prot"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24324:SF9">
        <property type="entry name" value="HOMEOBOX DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24324">
        <property type="entry name" value="HOMEOBOX PROTEIN HHEX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00046">
        <property type="entry name" value="Homeodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00389">
        <property type="entry name" value="HOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50071">
        <property type="entry name" value="HOMEOBOX_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3 4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2 3 4" id="KW-0371">Homeobox</keyword>
    <keyword evidence="3 4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Homeobox" evidence="5">
        <location>
            <begin position="18"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="Homeobox" evidence="3">
        <location>
            <begin position="20"/>
            <end position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OBZ86008.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="194" mass="22453" checksum="1CDA02B133B669B1" modified="2016-11-30" version="1">MDNRQLVTPVPSNDLKLSTKAKRRMRTSREEAAILESYYKQNPNPNSELKQEIAEVVNMGARNVHFWFQNRRAKDNKRKRLLKQQIEQGRIQTVLDLPPNDESVSSRFGIEVSYVQHQQPASLNPTRFNQTNMDQISSAQRQKGKFKLPPISTIMAPNNPGLSIPFYYYHSNFGIEDSMIQLAYLQDHAQNYSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NAN1</accession>
    <name>A0A1C7NAN1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Trafficking protein particle complex subunit BET3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">BET3</name>
        <name evidence="9" type="ORF">A0J61_05866</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Endoplasmic reticulum</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1 8">Golgi apparatus</location>
            <location evidence="1 8">cis-Golgi network</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the TRAPP small subunits family. BET3 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000330">
        <property type="protein sequence ID" value="OBZ86080.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NAN1"/>
    <dbReference type="FunCoup" id="A0A1C7NAN1">
        <property type="interactions" value="810"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NAN1"/>
    <dbReference type="InParanoid" id="A0A1C7NAN1"/>
    <dbReference type="OrthoDB" id="10262857at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030008">
        <property type="term" value="C:TRAPP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048193">
        <property type="term" value="P:Golgi vesicle transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016236">
        <property type="term" value="P:macroautophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd14942">
        <property type="entry name" value="TRAPPC3_bet3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1380.20:FF:000001">
        <property type="entry name" value="Trafficking protein particle complex subunit BET3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1380.20">
        <property type="entry name" value="Trafficking protein particle complex subunit 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016721">
        <property type="entry name" value="Bet3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024096">
        <property type="entry name" value="NO_sig/Golgi_transp_ligand-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007194">
        <property type="entry name" value="TRAPP_component"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13048">
        <property type="entry name" value="TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04051">
        <property type="entry name" value="TRAPP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF018293">
        <property type="entry name" value="TRAPP_I_complex_Bet3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111126">
        <property type="entry name" value="Ligand-binding domain in the NO signalling and Golgi transport"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="6 8" id="KW-0931">ER-Golgi transport</keyword>
    <keyword evidence="7 8" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006218"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRNR" id="PIRNR018293"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OBZ86080.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="193" mass="22106" checksum="CA0B0A2E73A283F4" modified="2016-11-30" version="1">MSLFPTVKQYKSLGEEVWKTKVDKINAELFTLTYGSMVVQLVKDFEDYSEVNKQLEKMGYNIGQRMIEDFLARSGIGRCSEFRDTAEAVSKVGFKMFLNITPTVTNWSSDNKEFSLVFEENPLADFVELPDEALEGGLWYSNVYCGVLRGALEMVQMQVETQFVSDVLRGDETTEMRVKLIRYLEEEVPVGED</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NAN6</accession>
    <name>A0A1C7NAN6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Hypoxia up-regulated protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">hyou1</name>
        <name evidence="7" type="ORF">A0J61_05860</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the heat shock protein 70 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000329">
        <property type="protein sequence ID" value="OBZ86090.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NAN6"/>
    <dbReference type="FunCoup" id="A0A1C7NAN6">
        <property type="interactions" value="280"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NAN6"/>
    <dbReference type="InParanoid" id="A0A1C7NAN6"/>
    <dbReference type="OrthoDB" id="10262720at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034663">
        <property type="term" value="C:endoplasmic reticulum chaperone complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030968">
        <property type="term" value="P:endoplasmic reticulum unfolded protein response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd10230">
        <property type="entry name" value="ASKHA_NBD_HSP70_HYOU1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.640.10:FF:000010">
        <property type="entry name" value="heat shock 70 kDa protein 14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1270.10:FF:000002">
        <property type="entry name" value="Heat shock 70 kDa protein 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.640.10">
        <property type="entry name" value="Actin, Chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.34.10">
        <property type="entry name" value="Substrate Binding Domain Of DNAk, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029048">
        <property type="entry name" value="HSP70_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029047">
        <property type="entry name" value="HSP70_peptide-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013126">
        <property type="entry name" value="Hsp_70_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45639">
        <property type="entry name" value="HSC70CB, ISOFORM G-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45639:SF3">
        <property type="entry name" value="HYPOXIA UP-REGULATED PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00012">
        <property type="entry name" value="HSP70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00301">
        <property type="entry name" value="HEATSHOCK70"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100934">
        <property type="entry name" value="Heat shock protein 70kD (HSP70), C-terminal subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0143">Chaperone</keyword>
    <keyword evidence="3" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="532"/>
            <end position="567"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="785"/>
            <end position="837"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="532"/>
            <end position="546"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="794"/>
            <end position="803"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="806"/>
            <end position="826"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="828"/>
            <end position="837"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007381"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OBZ86090.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="837" mass="93578" checksum="F976CAFFD7D6B31F" modified="2016-11-30" version="1">MSIDYGTEWFKVGLIKPGMPLDVALNKDSKRKTQSIVTIRHGERIYGSDAVSLAGRFPHLTYSNLKSIIGKRFNDPLVEEFRQRHVNQMVLDTERDMPTFIHNETTQLSVEELIAYQFQNAKQQASATAGENVKDCVITVTPFANQYERQSILDAAELAGLNVLSLMHDETAVALNYAVNREIGSVPENHIFYDMGAGSTVASIVTFSNVETKEKKTVRSEPQLEVRGVGFDRTLGGHELDVRLQQLLATEFMKAHQGRVKSDIKDSSNAMTRLMKESNRVKQILSANTETVAAIEGLHEGIDFKFKVTRAQLEDICQDLIARVKNPIETALKAAKMTVDDIQSVVLVGGGVRVPSVQKQLIDLVGAQKIAKNVNGDEAAVLGAAFRGASLSNQFRLSKQISIKDVIVFPVEVSYQTENKENEETIIFDKFNNINTRKTMTFNRATDFEFDVHYQKNSDAGGQGITKVKVTGLTEAMTKHKDDIKASNIPPKVRVTFELSSSGIVSVPEANLHVAKLTLKEKVKSFFGGKDNKETEEKIDESKASKQNETTVESADNAANKTAEEAEESISITKVPLTVEFVPTGNLPLTQKQKDVAKKRIAELDALDVRKKLREESRNMLEAFVYRVQDFLYDDVVSVIATEETIEAFREKLSETSDWLYDEGEHADTPVYISKLKELQSLESPIQHRFKEYKERAKNIELINNAVKLSRDFVDSIRAQSEEVRYHTEEELGTLTAATDKLAEWIKEKVEAQNKLADTEEPVLLTSEVKEKAKLVEEQLTKLLTKKKPKVPKKTTEVPKNDTTEESATSTSKAEEATASETSSETPDANKHPHDEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NBP9</accession>
    <name>A0A1C7NBP9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Putative sulfate permease C3H7.02</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">A0J61_05441</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000293">
        <property type="protein sequence ID" value="OBZ86513.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NBP9"/>
    <dbReference type="STRING" id="101091.A0A1C7NBP9"/>
    <dbReference type="InParanoid" id="A0A1C7NBP9"/>
    <dbReference type="OrthoDB" id="288203at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.750.24">
        <property type="entry name" value="STAS domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011547">
        <property type="entry name" value="SLC26A/SulP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001902">
        <property type="entry name" value="SLC26A/SulP_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002645">
        <property type="entry name" value="STAS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036513">
        <property type="entry name" value="STAS_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00815">
        <property type="entry name" value="sulP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11814">
        <property type="entry name" value="SULFATE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01740">
        <property type="entry name" value="STAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00916">
        <property type="entry name" value="Sulfate_transp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52091">
        <property type="entry name" value="SpoIIaa-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50801">
        <property type="entry name" value="STAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="47"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="77"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="102"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="135"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="161"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="211"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="250"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="304"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="344"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="387"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="438"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="domain" description="STAS" evidence="6">
        <location>
            <begin position="571"/>
            <end position="647"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OBZ86513.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="800" mass="89235" checksum="FBE900F5521CF5C7" modified="2016-11-30" version="1">MSTIYVDNPPIRYTDQLKHGIKQLPRMAQTYVKNLFPIVDWLPSYNMTWFSGDILAALTVGILVIPQSLAYAKIANLPPVFGLYTNFVGVLLYPLFGTSKDISIGVSAVMALMVGQVMGRFYLTEQYLSGEWTAADASIMLSLFAGFITLFIGIFRLGDLFHFICQPAIAGFMGGSGITIVINQLNKIFGIPGINTSEAPYLVFGKTLANLNHASVDAAFGLSAIIYLYLVKYLSEYLMRRYPQYSRWIFFFNTSRSVVVLIFSTLICFMINRFGYFTSSPVTVLGEIPAGLGHMAVPTIKTDVVSFFLADLPGIVILLIMEHGTISNSLGKLADYKVDMSQEILAIGLSNVISSFFCAFPSLGAFSRSAVNFKSGARTPLSSFFMGIIALLSLFFFTPAFTYVSTAALSSIIAYSVTDLISGPTVWRKYWDMHPSEFLIFACAYVISLFARIDVSVYVPIILSVIVQLYRSARPNYAFLERLDIDLELTDEKLKMQSNESSNDRMDEHVVFFPNNHPTVGPYLRPVAKGILCFQPQENIVFQNATFVFDKLTQEIKSSTRCGNLPSERLGDRSWNNASSVGKSLEKPLLHSVVLDLSGVHQLDYSGMEALIDAAIAAERYAGQSVNWYIVTGHSMLVRKTLLFAGFGNQRRDSKMNGRFLSDLRHGVSEGGHRPGVEGCCTNDVQPEIESIYHGDRSKHHEEYEQVVEIEKVQKKPHHHMLPKCFIGNRLQYDGSEDGISQTEMGNTSPSWCYCKNKIGPAVTDRIVAVHDRYPFFFQTVHDATRAALLRYHLDQSETA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NC25</accession>
    <name>A0A1C7NC25_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="13">ATP-binding cassette sub-family B member 6, mitochondrial</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">Abcb6_0</name>
        <name evidence="13" type="ORF">A0J61_07039</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the ABC transporter superfamily. ABCB family. Heavy Metal importer (TC 3.A.1.210) subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000456">
        <property type="protein sequence ID" value="OBZ84914.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NC25"/>
    <dbReference type="FunCoup" id="A0A1C7NC25">
        <property type="interactions" value="83"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NC25"/>
    <dbReference type="InParanoid" id="A0A1C7NC25"/>
    <dbReference type="OrthoDB" id="6500128at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005774">
        <property type="term" value="C:vacuolar membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015439">
        <property type="term" value="F:ABC-type heme transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd18581">
        <property type="entry name" value="ABC_6TM_ABCB6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03253">
        <property type="entry name" value="ABCC_ATM1_transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000186">
        <property type="entry name" value="ATP-binding cassette sub-family B member 7, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="entry name" value="ABC transporter type 1, transmembrane domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039421">
        <property type="entry name" value="Type_1_exporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24221">
        <property type="entry name" value="ATP-BINDING CASSETTE SUB-FAMILY B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24221:SF654">
        <property type="entry name" value="ATP-BINDING CASSETTE SUB-FAMILY B MEMBER 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="ABC transporter transmembrane region"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 13" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="20"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="65"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="96"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="129"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="237"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="356"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="382"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="468"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="499"/>
            <end position="520"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="12">
        <location>
            <begin position="242"/>
            <end position="525"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="11">
        <location>
            <begin position="559"/>
            <end position="793"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="804"/>
            <end position="836"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="853"/>
            <end position="916"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="855"/>
            <end position="866"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="867"/>
            <end position="883"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="9">
        <location>
            <begin position="904"/>
            <end position="916"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00024363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="OBZ84914.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="916" mass="103417" checksum="FC18D92BA373CF2B" modified="2016-11-30" version="1">MVNKLSLFPPSYSVDQFTWSSPFVIGPSVLLGVFFLVGVPRYLHNRHSSNGSSIISRRLTAFSKFLVFLCFVVVFTLIADATVIVTRAILEQYWTSSVLAFYIGISWLAWALSLFALADETQQFGKWYWTQYLFWILAVVSDTLVGWLWAMAILKPEPMEVIIVLLSIAHLFSTNHNTIQEASETSPLLTSTQNRQYGVVEVEAIDTSKKELSPFNGFVEKMQKLLPFIWPHRNLKLQLYVVLCFVIMILGFAVNLLAPRQIGQIVDNLKEGQFPWIPVLFYIGLKFLQGGSGLLQAIQNWLWIPIGQFTTREISLKTFSHLHSLSLGFHISRKTGEVLRVMDRGTSSVVSLLNQILFQIFPVWANIILISFFTTYMYAPSFGLIVFLTMIMYMYVTVAVTEWRTKYRRRMIELDNYARTKAVDSLLNFETVKYYNAESFEINRYKDAILEYQEADWKSSVSLNVLNLAQNAIITGGLLSGCLLFAYEVSSGELSAGDFVAFNMYMMQLYTPLHWFGTYYRMIQSNFIDMEKMLELLDEVQTVQDAPDAGELMVSQGHVVFDNVTFSYDGRQTALDGVSFTIPKGATVALVGPSGGGKSTILRLLFRFYDPNAGRIYIDGQDISQVTQLSLRKNIGVVPQDTVLFNDTIYYNIQYGDVNADETQIKRAAKAAQIHDKIETFPDGYETKVGERGLRLSGGEKQRVAIARTILKNPPIILLDEATSALDTTTERHIQQALSDMTKDRTTLVVAHRLSTIVNADLILVIKDGKVVESGSHEELIKLGIQNEEGGIYYEMWQKQLHDESDTLNDSQSGSSSSKRESSPAHPPRRVESQIVELVDTVEKKVIKTTPAEVETIELDAEEEDMPSNNTQEQTSDQQSQAEEQAVVDTESNADTASSSNNANKKKKKRKNKNRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NC49</accession>
    <name>A0A1C7NC49_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Velvet domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">A0J61_05283</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000281">
        <property type="protein sequence ID" value="OBZ86675.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NC49"/>
    <dbReference type="STRING" id="101091.A0A1C7NC49"/>
    <dbReference type="InParanoid" id="A0A1C7NC49"/>
    <dbReference type="OrthoDB" id="5599552at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.3960">
        <property type="entry name" value="Velvet domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021740">
        <property type="entry name" value="Velvet"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037525">
        <property type="entry name" value="Velvet_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038491">
        <property type="entry name" value="Velvet_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33572">
        <property type="entry name" value="SPORE DEVELOPMENT REGULATOR VOSA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33572:SF18">
        <property type="entry name" value="SPORE DEVELOPMENT REGULATOR VOSA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11754">
        <property type="entry name" value="Velvet"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51821">
        <property type="entry name" value="VELVET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Velvet" evidence="6">
        <location>
            <begin position="21"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="200"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="264"/>
            <end position="283"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51821"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OBZ86675.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="283" mass="32219" checksum="6DEE97E093A0D00B" modified="2016-11-30" version="1">MFNKILTSYSYPFASSSFKAASCLQPFELKIRQQPIQARINTTNDRDRRPLDPPPIVQILFHHPDNQINQSCLQDPYLIMAVTLVDSDRRELPNHSVPLALLGQTASSMYRLKDINNQDGGFFVFGDISVRLEGYFRLKLSLFQISTHGAVNLKSIYSNVFQVYSVKTFPGMLESTFLSRSFSDQGVRIRIRKEHRIQLHHSNKRKLSREEEQQQQAKRTISLLSSGSMPALSTFYNTNSNHSKPLHHKTCPTPTDTLLSFLNQKGAGKDPSSTYSILNDPAW</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NCL2</accession>
    <name>A0A1C7NCL2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 11">Chitin synthase</fullName>
            <ecNumber evidence="2 11">2.4.1.16</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">CHS2</name>
        <name evidence="14" type="ORF">A0J61_05210</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10 11">Polymerizes chitin, a structural polymer of the cell wall and septum, by transferring the sugar moiety of UDP-GlcNAc to the non-reducing end of the growing chitin polymer.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>[(1-&gt;4)-N-acetyl-beta-D-glucosaminyl](n) + UDP-N-acetyl-alpha-D-glucosamine = [(1-&gt;4)-N-acetyl-beta-D-glucosaminyl](n+1) + UDP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:16637"/>
            <dbReference type="Rhea" id="RHEA-COMP:9593"/>
            <dbReference type="Rhea" id="RHEA-COMP:9595"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17029"/>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
            <dbReference type="ChEBI" id="CHEBI:58223"/>
            <dbReference type="EC" id="2.4.1.16"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 11">Cell membrane</location>
            <topology evidence="1 11">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="11">Belongs to the chitin synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.16" evidence="2 11"/>
    <dbReference type="EMBL" id="LUGH01000275">
        <property type="protein sequence ID" value="OBZ86738.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NCL2"/>
    <dbReference type="FunCoup" id="A0A1C7NCL2">
        <property type="interactions" value="50"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NCL2"/>
    <dbReference type="InParanoid" id="A0A1C7NCL2"/>
    <dbReference type="OrthoDB" id="26569at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030428">
        <property type="term" value="C:cell septum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004100">
        <property type="term" value="F:chitin synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006031">
        <property type="term" value="P:chitin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd04190">
        <property type="entry name" value="Chitin_synth_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004835">
        <property type="entry name" value="Chitin_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013616">
        <property type="entry name" value="Chitin_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22914">
        <property type="entry name" value="CHITIN SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22914:SF9">
        <property type="entry name" value="CHITIN SYNTHASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01644">
        <property type="entry name" value="Chitin_synth_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08407">
        <property type="entry name" value="Chitin_synth_1N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 11" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="9 11" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="4 11" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="8 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 11" id="KW-0808">Transferase</keyword>
    <keyword evidence="6 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="506"/>
            <end position="525"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="546"/>
            <end position="568"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="588"/>
            <end position="607"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="619"/>
            <end position="646"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="666"/>
            <end position="688"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="801"/>
            <end position="822"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="834"/>
            <end position="856"/>
        </location>
    </feature>
    <feature type="domain" description="Chitin synthase N-terminal" evidence="13">
        <location>
            <begin position="119"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="16"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="56"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="12">
        <location>
            <begin position="66"/>
            <end position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012543"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00024009"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU366040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF08407"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="OBZ86738.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="861" mass="96544" checksum="EFFB3DA8353C9DE5" modified="2016-11-30" version="1">MYPPPPPDHKAEQDQYPLQDTQFSNQPPVTRSPFDDDHYPADQHMPAYDQQPLLASSMAPSSYPSNPYPPGPPSPGGGMMSPYPSFGGDSSPATPQYFNPPSPSMHYGEAPKRQPRRYKTTRQVKLTKGNLVLDCPVPTAYLKDVPLKEGKEFTHMRYTAATCDPKDFVSEGYTLRQQILGRKTELFIVLTMYNEDEVLFTRTMHGVMKNIAHLCSRDRSSTWGPASGGPGWHKVTVCVVSDGRTKINPRTLNVLSLLGVYQEGVAKNVVHGKPVTAHIYEYTTQISVDPDMEVKKAGSKNVAPCQMLFCLKEKNAKKINSHRWFFQAFGPVIDPHVCVLIDVGTKPGGTSIYHLWKAFDINSNIAGACGEIRAMAGTGGVALLNPLVAAQNFEYKMSNILDKPLESVFGYISVLPGAFSAYRFKALQNDIDGHGPLEKYFLGETQHGGDADIFTANMYLAEDRILCYELVAKKKAHWVLHYVSNSYGETDVPDKVDEFISQRRRWLNGSFFAGIYALYHWRKVWASDHSYIRKMMFMIEDIYNTYNLIFSWFALGNFYLTFFILTRALIPSVSGLTNPPFSETAASLLHHILNYIYIILLVVQFIIAMGNRPQGSKIAYTGSMVFFAFLMIYMMFAAIWITVIGVSDIVSSTDGSFISMLEQSSFRNIIISLCSTYVLYFVSSFLFLDPWHMFTSFLQYILLSPSYTNVLNIYAFCNTHDVSWGTKGDNSVATDLGVVKAKKDQSGDLAVEVEVPVEEKDINAAYIDAQVELTKKIEPEKSHRDAKTKQEDYYRSFRTRLVLSWIVSNLALVVAITNTSVITTGDRSAAYLGFILWSVAALSAIRFTGSTLYLIFKIFTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7ND44</accession>
    <name>A0A1C7ND44_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Threonine aspartase 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">TASP1</name>
        <name evidence="3" type="ORF">A0J61_04947</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000254">
        <property type="protein sequence ID" value="OBZ87001.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7ND44"/>
    <dbReference type="FunCoup" id="A0A1C7ND44">
        <property type="interactions" value="39"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7ND44"/>
    <dbReference type="InParanoid" id="A0A1C7ND44"/>
    <dbReference type="OrthoDB" id="2262349at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004298">
        <property type="term" value="F:threonine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051604">
        <property type="term" value="P:protein maturation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd04514">
        <property type="entry name" value="Taspase1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.30">
        <property type="entry name" value="(Glycosyl)asparaginase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000246">
        <property type="entry name" value="Peptidase_T2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037464">
        <property type="entry name" value="Taspase1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10188">
        <property type="entry name" value="L-ASPARAGINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10188:SF8">
        <property type="entry name" value="THREONINE ASPARTASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01112">
        <property type="entry name" value="Asparaginase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="N-terminal nucleophile aminohydrolases (Ntn hydrolases)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" description="Nucleophile" evidence="1">
        <location>
            <position position="182"/>
        </location>
    </feature>
    <feature type="site" description="Cleavage; by autolysis" evidence="2">
        <location>
            <begin position="181"/>
            <end position="182"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR600246-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR600246-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ87001.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="349" mass="37669" checksum="993B8F2C434F5D9E" modified="2016-11-30" version="1">MSEPAFIAVHIGAGNLSKSKERTYRLACAKACRQAMNLIKEKNATAIEAVTEAIKVLEDDPVTNAGYGSNLTLKGTVECDASIMAGKSATFGGVGAVSGLRNPIEVAYQMVLEAEKGLLTLGRIPPMLLAGEGAKEWAKSRGYTIIDDNELIEPSSQQTYLKHIQMLVEAQAAETTNLGHDTVGAICVDQFGDIASGVSSGGISLKPPGRVGEAAIYGSGCWAQNETDQLPGIACSTTGTGEQIMRTMFTYKCADRLLKEQDIQEAMIKTLTEDFLESPLLQIYHKKSVGTIALRKQKVKEKARIEFWFGHVTDDMGIGYMSETSVKPKTFISRKPSNEDFVSSGWLVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NDA4</accession>
    <name>A0A1C7NDA4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_05211</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000275">
        <property type="protein sequence ID" value="OBZ86739.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NDA4"/>
    <dbReference type="InParanoid" id="A0A1C7NDA4"/>
    <dbReference type="OrthoDB" id="10427508at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="220"/>
            <end position="257"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ86739.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="475" mass="52684" checksum="E4CEF2B1F0FDAE5B" modified="2016-11-30" version="1">MSLLHSPTFRKYFNNCDEKSTVPSFSGFITHHHKFIINHSDQRADEFQFWYCLFKENAKYFQIEVEKGDALKKWKELVCGQKSKNTKRSRYQKEIVEEFEAVAPAAPAAPDVPDVPVPALTAPAVPGATAATTTTAATVDFLAGFSRLRSRVAQELPKPDILKSIHVDLDKLLAIQGILRVSKSPHKEIKEVLGAKTCSKIKQELFGKSNRMPTSIKQDLEDALLDFADAEDDEEAAEELEDRLFSLKKKASGAAERVVKLFIKLYDNMKQEKQAADEMFLQSNIVPALCQLFKASRHHHPEGCNKVIFPGAAAVSECRPDFVVAVEGTSPFINVIGEIKGDGACNEGIALDAYRLGLFGLLMLREHKLKSSMVFQVTGLNATFYLCSRLGGIVAMVEIGTLSLPSTFEDFSLFGSQTQIMFDISMLYEQHCDVDHSLAAPEWKLVSYNAIKELYGISETSTVKASKTSSTDVLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NF04</accession>
    <name>A0A1C7NF04_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Myb-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_04259</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000204">
        <property type="protein sequence ID" value="OBZ87692.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NF04"/>
    <dbReference type="STRING" id="101091.A0A1C7NF04"/>
    <dbReference type="InParanoid" id="A0A1C7NF04"/>
    <dbReference type="OrthoDB" id="608866at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00167">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001005">
        <property type="entry name" value="SANT/Myb"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00249">
        <property type="entry name" value="Myb_DNA-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00717">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Myb-like" evidence="2">
        <location>
            <begin position="72"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00717"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ87692.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="178" mass="21165" checksum="371F71743EBD09CD" modified="2016-11-30" version="1">MTGDNTKMNEATPMDISTETDDQTKQRQEWVKRMRLKFCVREEFAQTKDMIFKDGTLNQEYFRPPKDAVEEQERKWTETERKLLIQGIEQYGIGHFGEISKELLPKWSTNELRIKCIRLIGRQNLQLYRDWKGNADDIAQEYEFNKKIGLEHGGWKQGVLVYDDEGRIEKALLEHHQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NF45</accession>
    <name>A0A1C7NF45_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_04224</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000201">
        <property type="protein sequence ID" value="OBZ87733.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NF45"/>
    <dbReference type="InParanoid" id="A0A1C7NF45"/>
    <dbReference type="OrthoDB" id="2445978at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="7"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="44"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="204"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="259"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="60"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="76"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="100"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="123"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="261"/>
            <end position="278"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ87733.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="292" mass="34345" checksum="70E15A286164DEF8" modified="2016-11-30" version="1">MMEVKEIFRLIGFLLVFLFPIAVIYLTGEHKKAPLLDDEEYEKRKRLQRQQQQQVESTKKNKKKNKKKQQAKVTVEEEEEEEEKVEEQQKPSKKQKKKNNKQEQAKSKPDTVKQESGPVAKETPIEEETKVPEEKIKEIDEHMDPTVNYARVMRIRPEEEEEEWEAVPYEEGWSQVKGRRQNNTAKSSPYDYVDNNAEVVETTSRYIPGLDKKQRENMARNAKKKQQKAAADALQAERLRKHQKELEKAKIEEFYSKGKGKNTQWGKNGQRTSSKVPNSYASFNEFGQLIWE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NFC8</accession>
    <name>A0A1C7NFC8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Multiple coagulation factor deficiency protein 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">Mcfd2</name>
        <name evidence="6" type="ORF">A0J61_04146</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000196">
        <property type="protein sequence ID" value="OBZ87805.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NFC8"/>
    <dbReference type="STRING" id="101091.A0A1C7NFC8"/>
    <dbReference type="InParanoid" id="A0A1C7NFC8"/>
    <dbReference type="OrthoDB" id="289247at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052110">
        <property type="entry name" value="MCFD2-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23104:SF1">
        <property type="entry name" value="EF-HAND DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23104">
        <property type="entry name" value="MULTIPLE COAGULATION FACTOR DEFICIENCY PROTEIN 2 NEURAL STEM CELL DERIVED NEURONAL SURVIVAL PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13499">
        <property type="entry name" value="EF-hand_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0106">Calcium</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008889668" evidence="4">
        <location>
            <begin position="17"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="5">
        <location>
            <begin position="51"/>
            <end position="86"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OBZ87805.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="128" mass="15130" checksum="E8758A147E06F07C" modified="2016-11-30" version="1">MRVFLILLLFFSYVYAEHKLDRHTSNYGDDHNKEHIQEHLKTLNKDNLELSEEDAIYYLFVIHDLNGDGFLDGHELRVAMSDFDHEELDLSLKEVTEMIDHVLEEDDINGDGLISWSEYLESQLYHDT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NFP1</accession>
    <name>A0A1C7NFP1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">A0J61_04002</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000186">
        <property type="protein sequence ID" value="OBZ87951.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NFP1"/>
    <dbReference type="STRING" id="101091.A0A1C7NFP1"/>
    <dbReference type="InParanoid" id="A0A1C7NFP1"/>
    <dbReference type="OrthoDB" id="1939603at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039327">
        <property type="entry name" value="CON7-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36167">
        <property type="entry name" value="C2H2 FINGER DOMAIN TRANSCRIPTION FACTOR (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36167:SF3">
        <property type="entry name" value="C2H2 FINGER DOMAIN TRANSCRIPTION FACTOR (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="4">
        <location>
            <begin position="266"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="135"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="301"/>
            <end position="335"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OBZ87951.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="362" mass="40219" checksum="664EB916C052AA96" modified="2016-11-30" version="1">MAQPTTATSTHAFPLSEPQTLLERRQQSAPYLQQLELPSLPPLSHLLTEKNGSKEGEMTKAATEAALAAATAVTASMITTTAQPLIQHDTHPVSFLPQTSITSAPTNLLYSYTNNRQNDSITAVDDTVALFPSSNLPINPPNPSLTSTRSSNPNPLDPSLMVNHSGFMEQHTLFNPVIAAGLTEPQQLIANPSHLNSPPMTALNTSENAMMNGFSTTGMGMTPSFIRRQSSVSSTSSDKAYSFVAIPGTNQRKRPRRRYDEIERLYHCNWPGCTKAYGTLNHLNAHVSMQQHGPKRHPAEFKEMRKEWRRLKKEREAAKKQAEAVYQEQQLLQQQMQPFPFTQPTYMPNNMSSLVNTYSFPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NG49</accession>
    <name>A0A1C7NG49_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_03931</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000181">
        <property type="protein sequence ID" value="OBZ88015.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NG49"/>
    <dbReference type="InParanoid" id="A0A1C7NG49"/>
    <dbReference type="OrthoDB" id="2202643at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="25"/>
            <end position="44"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ88015.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="268" mass="30004" checksum="553B80A3A2738C5E" modified="2016-11-30" version="1">MKLDEKYTVEEQIIRQKTRKRRCKLFLRLLSSIGLLALFMHLAYPAITKQDEAQITTFATTSSNANPRIILHTGFPPIENISGISIQSGKAAAIAFSPNPENFKEMSMGRSLHLTAGESWWDRLFPNRHVHLVNVQIPVASSLTKNHIQGKLSVCASKSSNHAQVPDLNKCVETASVNNNLDDDESQDDMFGVLEWIPDEAVVLKKSKLYWLVVQSEDNQPFNWIYSDAVGGANQYGTAYETEIGWRLKLEGEPVPSAIIMVADHPKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NG92</accession>
    <name>A0A1C7NG92_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">60S ribosomal protein L22</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">rpl22_1</name>
        <name evidence="4" type="ORF">A0J61_05567</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the eukaryotic ribosomal protein eL22 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000303">
        <property type="protein sequence ID" value="OBZ86384.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NG92"/>
    <dbReference type="FunCoup" id="A0A1C7NG92">
        <property type="interactions" value="424"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NG92"/>
    <dbReference type="InParanoid" id="A0A1C7NG92"/>
    <dbReference type="OrthoDB" id="10259820at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002181">
        <property type="term" value="P:cytoplasmic translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1360.210:FF:000001">
        <property type="entry name" value="60S ribosomal protein L22 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1360.210">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002671">
        <property type="entry name" value="Ribosomal_eL22"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038526">
        <property type="entry name" value="Ribosomal_eL22_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10064">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10064:SF31">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN EL22A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01776">
        <property type="entry name" value="Ribosomal_L22e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007817"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OBZ86384.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="121" mass="13821" checksum="019A242985CD91AB" modified="2016-11-30" version="1">MAPVKANTAAKKSKFVIDCSGPANDKIFDAAAFEKYLHDRIKVDGRTNNLGEAVTISRSADNKITVVANIAFSKRYLKYLTKKFLKKNQIRDWLRVIATDKQTFELRYFNIANDEEAEDEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NGF2</accession>
    <name>A0A1C7NGF2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Ribosome assembly factor mrt4</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">mrt4</name>
        <name evidence="8" type="ORF">A0J61_03744</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 6">Component of the ribosome assembly machinery. Nuclear paralog of the ribosomal protein P0, it binds pre-60S subunits at an early stage of assembly in the nucleolus, and is replaced by P0 in cytoplasmic pre-60S subunits and mature 80S ribosomes.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3 6">Associates with the pre-60S ribosomal particle.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="6">Nucleus</location>
            <location evidence="6">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the universal ribosomal protein uL10 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000168">
        <property type="protein sequence ID" value="OBZ88193.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NGF2"/>
    <dbReference type="FunCoup" id="A0A1C7NGF2">
        <property type="interactions" value="797"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NGF2"/>
    <dbReference type="InParanoid" id="A0A1C7NGF2"/>
    <dbReference type="OrthoDB" id="10262308at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005654">
        <property type="term" value="C:nucleoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030687">
        <property type="term" value="C:preribosome, large subunit precursor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032040">
        <property type="term" value="C:small-subunit processome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000956">
        <property type="term" value="P:nuclear-transcribed mRNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000027">
        <property type="term" value="P:ribosomal large subunit assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000055">
        <property type="term" value="P:ribosomal large subunit export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd05796">
        <property type="entry name" value="Ribosomal_P0_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.1730:FF:000005">
        <property type="entry name" value="Ribosome assembly factor mrt4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.105.20:FF:000003">
        <property type="entry name" value="Ribosome assembly factor mrt4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1730">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.105.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033867">
        <property type="entry name" value="Mrt4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001790">
        <property type="entry name" value="Ribosomal_uL10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040637">
        <property type="entry name" value="Ribosomal_uL10-like_insert"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043164">
        <property type="entry name" value="Ribosomal_uL10-like_insert_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043141">
        <property type="entry name" value="Ribosomal_uL10-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051742">
        <property type="entry name" value="Ribosome_Assembly_uL10"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45841:SF1">
        <property type="entry name" value="MRNA TURNOVER PROTEIN 4 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45841">
        <property type="entry name" value="MRNA TURNOVER PROTEIN 4 MRTO4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00466">
        <property type="entry name" value="Ribosomal_L10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17777">
        <property type="entry name" value="RL10P_insert"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160369">
        <property type="entry name" value="Ribosomal protein L10-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0690">Ribosome biogenesis</keyword>
    <feature type="domain" description="Large ribosomal subunit protein uL10-like insertion" evidence="7">
        <location>
            <begin position="125"/>
            <end position="197"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004046"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008889"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU364039"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF17777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OBZ88193.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="220" mass="25096" checksum="97BB3DD255190A71" modified="2016-11-30" version="1">MPKSKRSTVVSLTKTDKKGRGGKEKLFEDIQSCVDNYEYLYLYSVKDMRNTYLKEIRHDFNDSRFFYGKNRVMAKALGTTPEEEYKEGISGIAKNLNSEVGLLFTNKQPQEVKAYFDEFVKPDYARSGAIATETITLPEGPVKRGADPMPHNMEPLLRSLGMPTVLKNGIVTLLVPYTICMEGETLSTNQAHLLKLFYHQLAEFSVDMISYYHNGQVHEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NGH6</accession>
    <name>A0A1C7NGH6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Nucleoside diphosphate kinase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">A0J61_04295</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 11 12">Belongs to the NDK family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000207">
        <property type="protein sequence ID" value="OBZ87656.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NGH6"/>
    <dbReference type="STRING" id="101091.A0A1C7NGH6"/>
    <dbReference type="InParanoid" id="A0A1C7NGH6"/>
    <dbReference type="OrthoDB" id="2162449at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004550">
        <property type="term" value="F:nucleoside diphosphate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006241">
        <property type="term" value="P:CTP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006183">
        <property type="term" value="P:GTP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006228">
        <property type="term" value="P:UTP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.141">
        <property type="entry name" value="Nucleoside diphosphate kinase-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034907">
        <property type="entry name" value="NDK-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036850">
        <property type="entry name" value="NDK-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001564">
        <property type="entry name" value="Nucleoside_diP_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023005">
        <property type="entry name" value="Nucleoside_diP_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46161">
        <property type="entry name" value="NUCLEOSIDE DIPHOSPHATE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46161:SF3">
        <property type="entry name" value="NUCLEOSIDE DIPHOSPHATE KINASE DDB_G0292928-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00334">
        <property type="entry name" value="NDK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01243">
        <property type="entry name" value="NUCDPKINASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00562">
        <property type="entry name" value="NDK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54919">
        <property type="entry name" value="Nucleoside diphosphate kinase, NDK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00469">
        <property type="entry name" value="NDPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51374">
        <property type="entry name" value="NDPK_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0418">Kinase</keyword>
    <keyword evidence="9" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-0546">Nucleotide metabolism</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Nucleoside diphosphate kinase-like" evidence="14">
        <location>
            <begin position="1"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="125"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="215"/>
            <end position="890"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="941"/>
            <end position="975"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="125"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="135"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="222"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="248"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="302"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="346"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="369"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="453"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="511"/>
            <end position="526"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="531"/>
            <end position="541"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="550"/>
            <end position="561"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="602"/>
            <end position="613"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="631"/>
            <end position="642"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="647"/>
            <end position="663"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="734"/>
            <end position="747"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="807"/>
            <end position="825"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="13">
        <location>
            <begin position="826"/>
            <end position="835"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="849"/>
            <end position="858"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="875"/>
            <end position="888"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="941"/>
            <end position="956"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008142"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00017632"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00706"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU004011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="SMART" id="SM00562"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="OBZ87656.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="975" mass="107905" checksum="AD0C4A702DC20FA2" modified="2016-11-30" version="1">MQANHKNAIIEKIKEHGFTVVQEREIHLTKEKAGLFYQEHENKPFYDELTSWMSSKPIYALVLEKQDAVQAWRDLMGPTNAVKAKETHPTSMRALFGTDGSHNATHGSDSLESAKREIDLIFNQQEPEQTASSEENAKSKETVKDLSEDESVTSAVPEKATNDITPNDSRLVDTDQVIVQPSISAVEASSSEPGTQEHNVGTELLVTDKNNAAEKQNAVNKDQPEHVQLEESKSLTNKNHAEPISLDQQEKQNERTAEIETSLQHNDEPEDNESTNSSQEHAEDSDAIATDLSSQTQEEDAYLAHDEVESEKKKLEEKRFEKDDEPVIEKVQQLESTGAAQEDTNEILKEQPSQEDKPTQLEETTEQTALDKDEAQVPEDKETQAFKNDNEPEQQHQETHEQENHEAHKQKQEQVDHEVDEQKDHEENHEAPEQEGHEENQEHTQDKGPIQSAEETVTSRSADNGSSTSNVGATKDQQQSSDNPSDTIADDVGTHSSSKEAERKVKKVVKKTSPTTTTATTTGIKKPLSKPKTTMTSNGIRSATEKKTPAKATTATTTTKKLSPPIHKKKEGENENKNSATKATTKVARVPRVALLATQKKKAPEETEGDKPVKKTAVSTTVRKPVSSRPATGGASTAAGVASRKKLTTETKKPVTTTADKKTTSPPTSTLRKPTGSRDHTTSPGVSKLTTTSTESKLKAPKVTRSSTELKTADAKSKTVSRLTSGIRRVSPPNSTATANKKSATTTPVTPVKRSSKTLKTETRATNPNAKTRKETSSTTTKKIPQIKKKPLEKEPESVEEPQASHSLEKVKEEEEQHSIEKVQEEEPQEEEPQEEEKLSVDEVQEEPIESKEEHEEVNNTAEDPIQPNDIDAEPIQKEELEEVKLEDPSIVIEKDVEDVDVPSQQEDIQHNIQSSDAEIAAITSHKPQMASLLSKFENLNNDGSQSNQQLNTTLSKEIRAKSPNRISDMINRFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NGN9</accession>
    <name>A0A1C7NGN9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_03692</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000164">
        <property type="protein sequence ID" value="OBZ88257.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NGN9"/>
    <dbReference type="InParanoid" id="A0A1C7NGN9"/>
    <dbReference type="OrthoDB" id="2288540at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ88257.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="31" mass="3593" checksum="D74698AB3CCA1385" modified="2016-11-30" version="1" fragment="single">MSFNNLSNQQFTSEEYEDARSMATVDDEFSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NH68</accession>
    <name>A0A1C7NH68_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_03574</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000156">
        <property type="protein sequence ID" value="OBZ88385.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NH68"/>
    <dbReference type="STRING" id="101091.A0A1C7NH68"/>
    <dbReference type="InParanoid" id="A0A1C7NH68"/>
    <dbReference type="OrthoDB" id="2244769at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="53"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="86"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="169"/>
            <end position="191"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ88385.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="244" mass="26776" checksum="BC6444E9FA18C931" modified="2016-11-30" version="1">MPSRCCCIIPLRGGVIISGLIMLVVSGALLGATFTHKNPMVIHLSITHAILPWVYIGFTIAIAVISLLMVFSGSVAKLSMMRLTKLLLWLLVFLLTIWEAVCFILSLVNRSKTLTACEEANPSDTVSNANNATVSVGGYTTTFLGMEYGNTYGLANCGQAVQAGVIGNAILLFIGQLFMFYAATVVGSFTTKLRERKLGHRLRDLEWDDNLDELASTYRADAQNAPKYPLTDMNKKKKKKWFGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NHD7</accession>
    <name>A0A1C7NHD7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="3">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="primary">SNF1</name>
        <name evidence="16" type="ORF">A0J61_03403</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. SNF1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="3"/>
    <dbReference type="EMBL" id="LUGH01000145">
        <property type="protein sequence ID" value="OBZ88541.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NHD7"/>
    <dbReference type="FunCoup" id="A0A1C7NHD7">
        <property type="interactions" value="696"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NHD7"/>
    <dbReference type="InParanoid" id="A0A1C7NHD7"/>
    <dbReference type="OrthoDB" id="193931at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106310">
        <property type="term" value="F:protein serine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035556">
        <property type="term" value="P:intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd12122">
        <property type="entry name" value="AMPKA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd14334">
        <property type="entry name" value="UBA_SNF1_fungi"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000571">
        <property type="entry name" value="Maternal embryonic leucine zipper kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000236">
        <property type="entry name" value="Non-specific serine/threonine protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.10">
        <property type="entry name" value="DNA helicase RuvA subunit, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.310.80">
        <property type="entry name" value="Kinase associated domain 1, KA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032270">
        <property type="entry name" value="AMPK_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028375">
        <property type="entry name" value="KA1/Ssp2_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013896">
        <property type="entry name" value="SNF1_UBA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24346">
        <property type="entry name" value="MAP/MICROTUBULE AFFINITY-REGULATING KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24346:SF110">
        <property type="entry name" value="NON-SPECIFIC SERINE_THREONINE PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16579">
        <property type="entry name" value="AdenylateSensor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08587">
        <property type="entry name" value="UBA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103243">
        <property type="entry name" value="KA1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 13" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="7 16" id="KW-0418">Kinase</keyword>
    <keyword evidence="6 13" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="15">
        <location>
            <begin position="18"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="367"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="14">
        <location>
            <begin position="404"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="47"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="OBZ88541.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="574" mass="65302" checksum="32EE51CDCFE5B0F4" modified="2016-11-30" version="1">MNQNNTNNHSGRIKIGHYNIISTVGAGSFGKVKLAVHAITGQKVALKIVNRKKIASMDMGGRVKREIQYLKLLRHPHIIKLYEVITTPTDIIMVIEYAGRELFNYIVEKGKMAEDDARRFFQQIICAVEYCHRHKIVHSLLLDANNNVKIADFGLSNIMTDGDFLKTSCGSPNYAAPEVISGRLYAGPEVDVWSCGVILYVMLCGRLPFDDEYIPTLFKKINGEFNRFDLFFFTTSSQNPWFNKNLPAYLRPLPMTEQSGDISIDDDIVHELSKKMGYPTQTIQKALNEPTNNQFKVAYQLVVDRKRLLQDSEDTHIQSFLASSPPPWNTSLEDRLDASREDDYQLDPESSISVLSSSLPKTDYVQGKLTARERSSSNASSRGGILPIAPINGTPPPGAMAPSSMRQPSTRHLPINSPQKKPTKSKSRWHFGIRSKCPAWEVMLEIYRSLQNVGMEWKTMDPYHLRCRYKYSNIDLIVKFDLQLYKLESNSYLVDFKSVGTERTNVKPDTDENQVLKLLESEMASKLDIESKEDEKVTPYITQWNIQDDHTNTEHIQSVYPFLDVCSKLITDIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NHF4</accession>
    <name>A0A1C7NHF4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Homeobox protein 10</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">hbx10_3</name>
        <name evidence="9" type="ORF">A0J61_03391</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 5 6">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000145">
        <property type="protein sequence ID" value="OBZ88553.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NHF4"/>
    <dbReference type="STRING" id="101091.A0A1C7NHF4"/>
    <dbReference type="InParanoid" id="A0A1C7NHF4"/>
    <dbReference type="OrthoDB" id="6159439at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030154">
        <property type="term" value="P:cell differentiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00086">
        <property type="entry name" value="homeodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001356">
        <property type="entry name" value="HD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017970">
        <property type="entry name" value="Homeobox_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051000">
        <property type="entry name" value="Homeobox_DNA-bind_prot"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24324:SF5">
        <property type="entry name" value="HEMATOPOIETICALLY-EXPRESSED HOMEOBOX PROTEIN HHEX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24324">
        <property type="entry name" value="HOMEOBOX PROTEIN HHEX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00046">
        <property type="entry name" value="Homeodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00389">
        <property type="entry name" value="HOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00027">
        <property type="entry name" value="HOMEOBOX_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50071">
        <property type="entry name" value="HOMEOBOX_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 5 6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3 5 6" id="KW-0371">Homeobox</keyword>
    <keyword evidence="4 5 6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Homeobox" evidence="8">
        <location>
            <begin position="56"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="Homeobox" evidence="5">
        <location>
            <begin position="58"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="28"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="176"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="31"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OBZ88553.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="237" mass="26816" checksum="1824F4306B47BD11" modified="2016-11-30" version="1">MQDEENRRSSLAISALLNDDIDTKISEYTFDRSSSTSPVLSSGQTSPTLAKQIPSQLSKAKRKRISPSQYNRLMEVFEQTDTPSSEIRENLANELDMTKREVQVWFQNRRAKMNRTRNTTNNRRHSAFIPPPLTRTTSAIDSNQLAYHQHPPSLSQSQLPSFAHVSSPYVLTPVSTGPLRHHDHHPLAYSKDLPPSPPPTKHIFPYPYKRESSNIDLLASAAEIVSTDRKEMGHSKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NHY5</accession>
    <name>A0A1C7NHY5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_03351</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000142">
        <property type="protein sequence ID" value="OBZ88600.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NHY5"/>
    <dbReference type="InParanoid" id="A0A1C7NHY5"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="37"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="37"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="50"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="79"/>
            <end position="91"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ88600.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="98" mass="11378" checksum="0F31AEA48E6D32AF" modified="2016-11-30" version="1">MILPSYVVQISPLSFISFDNPNPDVFSIWPYRTEINSRDKHEFNRDHASVNLNTRTRVSYSSHSDEDDKQMVHQRRPRPQNPRPPSSPPMPVTTLSTD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NJQ2</accession>
    <name>A0A1C7NJQ2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Small ribosomal subunit protein uS17</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="14">40S ribosomal protein S11</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="16" type="primary">rps11a</name>
        <name evidence="16" type="ORF">A0J61_02663</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the universal ribosomal protein uS17 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000103">
        <property type="protein sequence ID" value="OBZ89295.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NJQ2"/>
    <dbReference type="FunCoup" id="A0A1C7NJQ2">
        <property type="interactions" value="484"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NJQ2"/>
    <dbReference type="InParanoid" id="A0A1C7NJQ2"/>
    <dbReference type="OrthoDB" id="10254436at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022627">
        <property type="term" value="C:cytosolic small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00364">
        <property type="entry name" value="Ribosomal_uS17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.1000:FF:000008">
        <property type="entry name" value="40S ribosomal protein S11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000266">
        <property type="entry name" value="Ribosomal_uS17"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019979">
        <property type="entry name" value="Ribosomal_uS17_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032440">
        <property type="entry name" value="Ribosomal_uS17_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10744">
        <property type="entry name" value="40S RIBOSOMAL PROTEIN S11 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10744:SF9">
        <property type="entry name" value="40S RIBOSOMAL PROTEIN S11-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00366">
        <property type="entry name" value="Ribosomal_S17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16205">
        <property type="entry name" value="Ribosomal_S17_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00056">
        <property type="entry name" value="RIBOSOMAL_S17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0007">Acetylation</keyword>
    <keyword evidence="7" id="KW-0164">Citrullination</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="12" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="3" id="KW-0488">Methylation</keyword>
    <keyword evidence="10" id="KW-0564">Palmitate</keyword>
    <keyword evidence="5" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="8 16" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="6" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="Small ribosomal subunit protein uS17 N-terminal" evidence="15">
        <location>
            <begin position="4"/>
            <end position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022934"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022990"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00035164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00035471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF16205"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="OBZ89295.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="153" mass="17409" checksum="6A4C5237CC92B235" modified="2016-11-30" version="1">MDHQTEKAFQKQAGIFQNSKDAKKRNQRWFKEVGNGFKTPKEAKTGTYIDKKCPFVGEVNIQGRILTGVVVSTKMKRTLVVRRDYLHYIPKYNRYEKRHKNISAHVSPAFDNAAIESGDVVTIGQCRPLSKTVRFNVLKVSKAKGAAKSFSKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NJQ5</accession>
    <name>A0A1C7NJQ5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Tyrosine-protein phosphatase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">A0J61_02608</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000100">
        <property type="protein sequence ID" value="OBZ89347.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NJQ5"/>
    <dbReference type="FunCoup" id="A0A1C7NJQ5">
        <property type="interactions" value="157"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NJQ5"/>
    <dbReference type="InParanoid" id="A0A1C7NJQ5"/>
    <dbReference type="OrthoDB" id="6375174at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052840">
        <property type="term" value="F:inositol diphosphate tetrakisphosphate diphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016791">
        <property type="term" value="F:phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.190.10:FF:000035">
        <property type="entry name" value="Tyrosine phosphatase, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.190.10">
        <property type="entry name" value="Protein tyrosine phosphatase superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020428">
        <property type="entry name" value="PFA-DSPs"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029021">
        <property type="entry name" value="Prot-tyrosine_phosphatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004861">
        <property type="entry name" value="Siw14-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020422">
        <property type="entry name" value="TYR_PHOSPHATASE_DUAL_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31126:SF48">
        <property type="entry name" value="INOSITOL PHOSPHATASE SIW14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31126">
        <property type="entry name" value="TYROSINE-PROTEIN PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03162">
        <property type="entry name" value="Y_phosphatase2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01911">
        <property type="entry name" value="PFDSPHPHTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52799">
        <property type="entry name" value="(Phosphotyrosine protein) phosphatases II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50054">
        <property type="entry name" value="TYR_PHOSPHATASE_DUAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tyrosine-protein phosphatase" evidence="4">
        <location>
            <begin position="8"/>
            <end position="160"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OBZ89347.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="163" mass="19033" checksum="419FB61EFCFAEDF1" modified="2016-11-30" version="1">MPLVPPLNFAMIASGVYRSGHPNKQNFAFLRKLGLKTILYFAMEEYPPEMQHFVEHEGIEVLHYRTEGNKEPFVEVNHEDISHALVKLLDKTSHPVLIHCLKGKHRIGCLVGCLRKIQNWSMTSIFDEYRKFAGTKVLADQEFIETFNHEQVPYNEKNRPKWL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NK90</accession>
    <name>A0A1C7NK90_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Phorbol-ester/DAG-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">A0J61_02394</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000089">
        <property type="protein sequence ID" value="OBZ89561.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NK90"/>
    <dbReference type="InParanoid" id="A0A1C7NK90"/>
    <dbReference type="OrthoDB" id="6270916at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.60.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046349">
        <property type="entry name" value="C1-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002219">
        <property type="entry name" value="PKC_DAG/PE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024855">
        <property type="entry name" value="UNC79"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21696">
        <property type="entry name" value="PROTEIN UNC-79 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21696:SF2">
        <property type="entry name" value="PROTEIN UNC-79 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57889">
        <property type="entry name" value="Cysteine-rich domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50081">
        <property type="entry name" value="ZF_DAG_PE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Phorbol-ester/DAG-type" evidence="4">
        <location>
            <begin position="648"/>
            <end position="698"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="133"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="279"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="485"/>
            <end position="514"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="27"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="134"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="284"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="497"/>
            <end position="506"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50081"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OBZ89561.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="2489" mass="282292" checksum="F8A83ECC4C48A904" modified="2016-11-30" version="1">MFSNAQNQPQGATIINIHSPEDEMQPVTESSFGRRPSNTSRPTSQPSAQSHAKPKPSPKVEEYRKMIQHITNKIIKRKRPPTALSHLNDFSRTTQVNDTFENDDTIDLLIQLRSALMVCHQIGLSSQVLFQGERTPTNSPLSSRSNSPLPSPRIESPIRSPEPFGSAVPLFSIANNQSSKSHTEFDIILYILSDLVLNDSRYKTSNPKPSRPPFTMQAILIDLATILTQIRDDSSGLYLIGTVFMPAFESFSEGTMLGRLLAFFIDSLLPKLMKCKDEPKSRLNNKTTNNESSTKAVQTKTVHPNTPTINIQSAEPDQLSVPTKASHLTIDTRPLTVAAQSSSPISPAALSVNSNYQAQSLSAYHAFSLFTPLLFFMIQYLDPYLAAQPSRAQQDNLTYTLTRQANSIHNFHKALSYMMSCKPDLYLDLLDIISHSTSEVKFRACQVLFNYYIVSVGHVVVADPLPRLGTQEELEILDQRRLQQELEEEHQRNHQQPNSHSTTQNRTTKDPTRAELVEDDWAEEQHVWYSYMFDEDDSNTKILSNNPFSFGAYKSPTDSHCKECFKPIQGCGLHCFQCRSNIHIDCYNSKAQMDDHGMLFYMKAGGIQKVVAPQRCIVPPQPRCRDMVDRGLLQWNIKSSAPKVGLLGHLFQLVNLFTATLCICCHLPLWGTCLQAYQCTTCFRFIHPECLAEIEESNNLSSVHSHNPLSPSTSAHRLQKCSSKSSLQESDITISQADLEKSLAAFYDDALSTQSEFLKGKSFEEVGLMVNTLLIQENILHCGVASGCMIITQESDDPLLLTTDTLHNQGRPSSHSALLSQAINAYSDFLESAENVHVSTFFVDFFDHSDFTAVKHLMNKQDFLYHLGAMMKSLVTSSDDGISNFSMNNRQHKRASDNSQGFLQVSPSPFAANTWEDDEYNNELNESHTPNENLDRSVLLSWIMTNLNFKSLRAAEILLQHMRNIGIFERFDASPLLFVRHVTAEKVENEPAVQCIFPVPCAIDFSASVESLVNSIEACVQDIDLSINECGLLLLTRRCWPDRFMSHYTQERLIRAIIGWTFDEDERLLALHAEITSLNRHSSLHHSKQQNKWVQAALLARMKVPASAERSRQSTFHVNTTAPSVNSGASNIYVTTRAGLKDRYVVRWMSAIQGMNPETYTDMIFNAIEEIIDSKREECILPDWEELSEVKNHTLQKYELFINYITKLKNNGLTFNSLDSILEKWFESTYTEFQILGMLQDKEPSELRNLVKLCSTKSTHGRIPSNMSSSSVNPIDLVVSQFQNKDEHVIDRGMRWLTLMTYSGVDLTSNALSRISKLLIESKVALKTIVEFVKIIWFQVIHINAFAARRAVIADIVGYLSESTSETLELFNNDRDLPDESLIDVQSFVKYCAALVCFAYGCSTEEIIKATLVPFTGDHTIKAGKKSVTVDHDLIEVDENTPSIDNMLSFLKYDQLNLREYVVKMFYCITQWGHGISNKEELINACISKLIPVVWELLSPAHDHISSINLNLLMHLINVDVRYFEACVFKIFEDANWEVRYQGLDNLFGLFTKMDAAFQTEWLKLLSKLGPVFSYFVGCLWDKEEYVRLKAFALIRSFGTLHLQSAFRCWEAYFLTATDRQKMSLVSLMTQLNALFPEWQVLQWESLLEALESKLAINALDDYSHVSTGRDFLTKESRAPEQLSAESENVQALMLTLALQMLSSHLNIEPSQLYRLKFILVQQMNFEDCHYINEGGEIAVSFGALRYDPDNSSQVAVMLTCTRGLKKIMDSFAPLPAEAVANIASDSFEQNRINLAENSSPGVYFIDVVLKAVNSGIELTKMGHMMLKTWLEIILIIVYKHNILEREYEQSIVTCMKHIIEILTEQISDENKLLILEILKCLLKRSDHLTAMVLSKQILALGKLMTKLGTRHSEPVYLKAKQFLKSAFLRFAVAGLFVLMFKNQAASDISQGDVDLFFVLRTVIDPDDIIPDEEFQGETIYLRDQPVRDVLDKLMKQQMERKAFSTVLFNTSKYVEAVHSSPYAESILNDYAGFLQALVKHTSDWRRSDWNINPVFTMSAILLKEHPYHHVILVPSIQAVLKHGLSNCTIQADAVVKLMIAYTITVPGAKPSNNAFARILVEEVKNALSVLTRPSKDTLLVLLQIVLYDIKPAGQEWYNTIEASFLGKSQGATNYSHKSYFESKLFDLLPYFVNYLKRTTTSQQFTRKDFKIYSCIAQLVVLMASKDPKLTVIIFGYLKLEEGVHCLRFLNWFILTLLKEKADILLPEIIRYENVLTELLVRTLNTVEIDFHAPDLNFSYSSANEKVLLSFLLIKSCSLMKMRYILTTTDKVNSPDSPMFWMAIWPAIRRLLDSIESSTLFTVGNVGVSIWNTFLSLLQFLFATRNAIVTVNAYEWNELLSTLMKKIKSENNTFQGNDIGIEQLITLDEFQKQIEKIKIMFDVPPVEVPLPVIVDQMLIELRDAMRLQAESIAFQGSSRDLMHTLGSTF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NKB1</accession>
    <name>A0A1C7NKB1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Trafficking protein particle complex subunit 12</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">Trappc12</name>
        <name evidence="2" type="ORF">A0J61_02373</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000088">
        <property type="protein sequence ID" value="OBZ89572.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NKB1"/>
    <dbReference type="STRING" id="101091.A0A1C7NKB1"/>
    <dbReference type="InParanoid" id="A0A1C7NKB1"/>
    <dbReference type="OrthoDB" id="428342at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030008">
        <property type="term" value="C:TRAPP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21581">
        <property type="entry name" value="D-ALANYL-D-ALANINE CARBOXYPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21581:SF6">
        <property type="entry name" value="TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14559">
        <property type="entry name" value="TPR_19"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="39"/>
            <end position="49"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ89572.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="400" mass="45122" checksum="5E36D0424C20A01B" modified="2016-11-30" version="1">METDASVLLQSVVLPSSIDETPSPPSKPARNKPERQPSIGPSLSSSTNFYDIPGSDALNDLLERYIPPQERPERDMESDKTANKGPETLVMNQRWRAIAKHARQQIVQSDPAQTEAILKLWFMRLLALTKLGLCQLASAEFEKLGDLDRVELTDPITHRSLVPFELRILFATLPSYLEYPHLALERITLLAVYCKKKQKTEDPTVWHQREIQTYLVLATHWIHMRDYASAAKTMKLILTMAPDHADALAGIGRLYLQMGDLVSADHILQRMKTLYGDQPNAKEAIDILSAFQCMAQGEWIQARDCLQQVYQTNPENLLAINNLAVCEVYLGHLDKAVERLETLTSQNPTSAGTCETAIMNMCTLYELRCEDAIEKKKQVLMQVARWAGDSFGADCLKLQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NKG4</accession>
    <name>A0A1C7NKG4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">Smarcd3</name>
        <name evidence="3" type="ORF">A0J61_02316</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000085">
        <property type="protein sequence ID" value="OBZ89633.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NKG4"/>
    <dbReference type="FunCoup" id="A0A1C7NKG4">
        <property type="interactions" value="611"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NKG4"/>
    <dbReference type="InParanoid" id="A0A1C7NKG4"/>
    <dbReference type="OrthoDB" id="10263741at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd10568">
        <property type="entry name" value="SWIB_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.245.10">
        <property type="entry name" value="SWIB/MDM2 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019835">
        <property type="entry name" value="SWIB_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036885">
        <property type="entry name" value="SWIB_MDM2_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003121">
        <property type="entry name" value="SWIB_MDM2_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13844">
        <property type="entry name" value="SWI/SNF-RELATED MATRIX-ASSOCIATED ACTIN-DEPENDENT REGULATOR OF CHROMATIN SUBFAMILY D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02201">
        <property type="entry name" value="SWIB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00151">
        <property type="entry name" value="SWIB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47592">
        <property type="entry name" value="SWIB/MDM2 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51925">
        <property type="entry name" value="SWIB_MDM2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DM2" evidence="2">
        <location>
            <begin position="258"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="17"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="43"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51925"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ89633.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="480" mass="55196" checksum="40FA4DFA9A818E9C" modified="2016-11-30" version="1">MQSQPQMFQQHPGAMPVVPPQGLPQGIPPPQGLPQGIPPPQGMPQGIPQGIPAQGMPHQGIPPPPMPGAMPYRKRPSEADTLSKHIKKKRPTDKNIPASIDSFVPESKLYPELVDFETKLDATIMRKRLDIQEALGKPTKIRRTLRLFISNTASSHQSPEDENTFDLNNGNVPTWTLKIEGQLLNPEQKNQKEEQPEPKLTSFFRSIVIELDRDLNMYPEGNLIEWQKQPNAADFDVIQIKRKGDMDVKVKLAFHLDHNPQKFKLSPPLADLLDVKVETKPQIVMGIWNYCKYHKLQDAEDKRLIRCDPRLAQIFGYPQLHFSQLPELILQHLSRPDPIIIEYTIRVDKPFHASSKAYDIEVELDSMVRQKMMQIVSSTQTQKEIMALDDKIVQCVQSINNSKIKRDFLLQFSKQPVEFINKWIASQARDLEVILGESKVNLEEMRQTEFYKQPWMKEAVFHYLTTKTQQRMQELLGFTQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NKJ5</accession>
    <name>A0A1C7NKJ5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="2">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">nrc-2_0</name>
        <name evidence="13" type="ORF">A0J61_02629</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="2"/>
    <dbReference type="EMBL" id="LUGH01000101">
        <property type="protein sequence ID" value="OBZ89339.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NKJ5"/>
    <dbReference type="STRING" id="101091.A0A1C7NKJ5"/>
    <dbReference type="InParanoid" id="A0A1C7NKJ5"/>
    <dbReference type="OrthoDB" id="432483at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05574">
        <property type="entry name" value="STKc_phototropin_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000524">
        <property type="entry name" value="Non-specific serine/threonine protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000121">
        <property type="entry name" value="Serine/threonine-protein kinase nrc-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45637">
        <property type="entry name" value="FLIPPASE KINASE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7 13" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="12">
        <location>
            <begin position="111"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="442"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="457"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="471"/>
            <end position="481"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009903"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="OBZ89339.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="481" mass="54165" checksum="34E2AB0A38650522" modified="2016-11-30" version="1">MSIPCSPAPSYQPDKLFQTRIKLNNQSLEADLPENDHGIRRVSSVPSTTDYFDNNDNRFLTASNTSNYSTSTPNVSNQYAANSAPVSPKPPFRSSSYTLEKKQVQVGPTDFEKVRLLGRGDVGKVYLVKHKSTEKLYALKVLSKKEMISRNKIKRAVAEQTILATVNHPFIVPLYHSFQSSNYLYFCMEFCVGGEFFRALQYRPGRVLKENEAKFYAAEVVAALEYLHLMGIVFRDLKPENILLHESGHLMLSDFDLSIQSPTAALPTLVRPNSPFSKKPLVDTRSCMNIRTNSFVGTEEYLAPEVIRGNGHTSTVDWWALGIFVYEMMCGYTPFKGPTRDDTFDLILNNPVEFPDYANSPYGRGLSMSSDCKSFIKKLLNKNENKRLGSHAGASEVKAHSFFKSINFALLRNMKPPIKPNKDKPIRAVHFTRMKESVSFDLHADSRADSLSTPPSTDDDEEEAEVDPFGSFSSVTIRRQD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NL64</accession>
    <name>A0A1C7NL64_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">37S ribosomal protein subunit sws2, mitochondrial</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">sws2</name>
        <name evidence="5" type="ORF">A0J61_02137</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the universal ribosomal protein uS13 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000077">
        <property type="protein sequence ID" value="OBZ89815.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NL64"/>
    <dbReference type="FunCoup" id="A0A1C7NL64">
        <property type="interactions" value="247"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NL64"/>
    <dbReference type="InParanoid" id="A0A1C7NL64"/>
    <dbReference type="OrthoDB" id="525520at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015935">
        <property type="term" value="C:small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.50:FF:000001">
        <property type="entry name" value="30S ribosomal protein S13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.910.10">
        <property type="entry name" value="30s ribosomal protein s13, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01315">
        <property type="entry name" value="Ribosomal_uS13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027437">
        <property type="entry name" value="Rbsml_uS13_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001892">
        <property type="entry name" value="Ribosomal_uS13"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010979">
        <property type="entry name" value="Ribosomal_uS13-like_H2TH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10871">
        <property type="entry name" value="30S RIBOSOMAL PROTEIN S13/40S RIBOSOMAL PROTEIN S18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10871:SF1">
        <property type="entry name" value="SMALL RIBOSOMAL SUBUNIT PROTEIN US13M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00416">
        <property type="entry name" value="Ribosomal_S13"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002134">
        <property type="entry name" value="Ribosomal_S13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46946">
        <property type="entry name" value="S13-like H2TH domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50159">
        <property type="entry name" value="RIBOSOMAL_S13_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 5" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003830"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OBZ89815.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="141" mass="16281" checksum="FD947CB88C374538" modified="2016-11-30" version="1">MLHLLGVNLPDRKIVSTALQYFYGIGEPTAQKLCQKLSIPPTLKVAELSEVQVNELTNTLAGMTIETDLKRQIREHVMHHRNIGNYIGRRHAMSLPVRGQRTRNNAKNAKKLNGRWVQRRGFSMWTQLQQSPLTNFLEKYM</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NLC1</accession>
    <name>A0A1C7NLC1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uracil catabolism protein 4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">URC4_0</name>
        <name evidence="1" type="ORF">A0J61_02195</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000079">
        <property type="protein sequence ID" value="OBZ89770.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NLC1"/>
    <dbReference type="InParanoid" id="A0A1C7NLC1"/>
    <dbReference type="OrthoDB" id="2153176at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012469">
        <property type="entry name" value="DUF1688"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31687">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31687:SF3">
        <property type="entry name" value="PROTEIN URG3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07958">
        <property type="entry name" value="DUF1688"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ89770.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="417" mass="46611" checksum="A27E3B23784D832D" modified="2016-11-30" version="1">MTILPQDYLRSLKAIRERCEKVYEAPEKLIAFDIDESRLPAIVDHVTNTTTRRFPQLDQIPPHSRLRHFDPVQLQSLRDQWAQQGVDQVEQARRLVDLVIVSVLVDAGAGQVWKYKTKNGVSIGRSEGLALASFDMFLQGYFSSQNEVPDSVDAAGLDNVTVKKMTEGFQVTETNPMVGLEGRSNLLKRLARVLEEQSVYFPSIYRESPRPGNLIDFLLSSAQENKNTVHIETLWEAVMSLSGIWPARLEVNGVAMGDVWMCDSLVDQGNFENLVPFHKLSQWLTYSLIESIELSLDIKIEGVEQMTGLPEYRNGGLLVDYGLLTLKLEQAKRGGATQEGQLPAFEGSDPVIVEWRALTVTYLDKIKKEVEKKLGRTLSLAQVLEGGTWTAGREIAAKLRPEDGGPPIVIKSDGTIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NLL6</accession>
    <name>A0A1C7NLL6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Ribosomal RNA-processing protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">SPBC9B6.07</name>
        <name evidence="5" type="ORF">A0J61_01927</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the RRP1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000067">
        <property type="protein sequence ID" value="OBZ90023.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NLL6"/>
    <dbReference type="FunCoup" id="A0A1C7NLL6">
        <property type="interactions" value="28"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NLL6"/>
    <dbReference type="InParanoid" id="A0A1C7NLL6"/>
    <dbReference type="OrthoDB" id="2019504at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030687">
        <property type="term" value="C:preribosome, large subunit precursor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030688">
        <property type="term" value="C:preribosome, small subunit precursor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010301">
        <property type="entry name" value="RRP1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13026">
        <property type="entry name" value="NNP-1 PROTEIN NOVEL NUCLEAR PROTEIN 1 NOP52"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13026:SF0">
        <property type="entry name" value="RIBOSOMAL RNA PROCESSING 1B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05997">
        <property type="entry name" value="Nop52"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0698">rRNA processing</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006374"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OBZ90023.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="232" mass="27258" checksum="AC74FD99861F1760" modified="2016-11-30" version="1">MDVDPTYLPLGKQLAANEKKTRDKAVRSLRRFLSTGNDLNEIELIKLWKGLFYCFWMSDKPLIQQALANDLGALVMELPATNAIPFLKACWKVHCQEWHGIDRIRLDKYYMLLRRVIYFSFQFLARESWDQTFCEAYADMLIEGPMSPTDRKNPDAIRYHIIDIYFEELEKVLDDVRSRSDDSDLQIPMEEINRPFVVLAKEGTTKILRKKAKEALEAHEEEMKAMNEEDEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NLZ8</accession>
    <name>A0A1C7NLZ8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Propionyl-CoA carboxylase alpha chain, mitochondrial</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">Propanoyl-CoA:carbon dioxide ligase subunit alpha</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="17" type="primary">PCCA</name>
        <name evidence="17" type="ORF">A0J61_01877</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>butanoyl-CoA + hydrogencarbonate + ATP = (2S)-ethylmalonyl-CoA + ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:59520"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17544"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57371"/>
            <dbReference type="ChEBI" id="CHEBI:60909"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="12">
            <dbReference type="Rhea" id="RHEA:59521"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>biotin</name>
            <dbReference type="ChEBI" id="CHEBI:57586"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion matrix</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000065">
        <property type="protein sequence ID" value="OBZ90058.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NLZ8"/>
    <dbReference type="STRING" id="101091.A0A1C7NLZ8"/>
    <dbReference type="InParanoid" id="A0A1C7NLZ8"/>
    <dbReference type="OrthoDB" id="196847at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004658">
        <property type="term" value="F:propionyl-CoA carboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06850">
        <property type="entry name" value="biotinyl_domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.100:FF:000003">
        <property type="entry name" value="Acetyl-CoA carboxylase biotin carboxyl carrier protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1490.20:FF:000018">
        <property type="entry name" value="Biotin carboxylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.470.20:FF:000028">
        <property type="entry name" value="Methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.20:FF:000010">
        <property type="entry name" value="Propionyl-CoA carboxylase subunit alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.700.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.20">
        <property type="entry name" value="ATP-grasp fold, A domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.470.20">
        <property type="entry name" value="ATP-grasp fold, B domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011761">
        <property type="entry name" value="ATP-grasp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013815">
        <property type="entry name" value="ATP_grasp_subdomain_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005481">
        <property type="entry name" value="BC-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050856">
        <property type="entry name" value="Biotin_carboxylase_complex"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011764">
        <property type="entry name" value="Biotin_carboxylation_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005482">
        <property type="entry name" value="Biotin_COase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000089">
        <property type="entry name" value="Biotin_lipoyl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005479">
        <property type="entry name" value="CPAse_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041265">
        <property type="entry name" value="PCC_BT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016185">
        <property type="entry name" value="PreATP-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011054">
        <property type="entry name" value="Rudment_hybrid_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011053">
        <property type="entry name" value="Single_hybrid_motif"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18866">
        <property type="entry name" value="CARBOXYLASE:PYRUVATE/ACETYL-COA/PROPIONYL-COA CARBOXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18866:SF33">
        <property type="entry name" value="METHYLCROTONOYL-COA CARBOXYLASE SUBUNIT ALPHA, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02785">
        <property type="entry name" value="Biotin_carb_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00289">
        <property type="entry name" value="Biotin_carb_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00364">
        <property type="entry name" value="Biotin_lipoyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02786">
        <property type="entry name" value="CPSase_L_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18140">
        <property type="entry name" value="PCC_BT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00878">
        <property type="entry name" value="Biotin_carb_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56059">
        <property type="entry name" value="Glutathione synthetase ATP-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52440">
        <property type="entry name" value="PreATP-grasp domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51246">
        <property type="entry name" value="Rudiment single hybrid motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51230">
        <property type="entry name" value="Single hybrid motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50975">
        <property type="entry name" value="ATP_GRASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50979">
        <property type="entry name" value="BC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50968">
        <property type="entry name" value="BIOTINYL_LIPOYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00866">
        <property type="entry name" value="CPSASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00867">
        <property type="entry name" value="CPSASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7 13" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10" id="KW-0092">Biotin</keyword>
    <keyword evidence="4" id="KW-0436">Ligase</keyword>
    <keyword evidence="9" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 13" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Biotin carboxylation" evidence="16">
        <location>
            <begin position="64"/>
            <end position="506"/>
        </location>
    </feature>
    <feature type="domain" description="ATP-grasp" evidence="15">
        <location>
            <begin position="183"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="domain" description="Lipoyl-binding" evidence="14">
        <location>
            <begin position="649"/>
            <end position="726"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001953"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004305"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00018058"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00031557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00048208"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="OBZ90058.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="733" mass="82412" checksum="AA5E2600F22BC109" modified="2016-11-30" version="1">MYARRISSLSRQTSLNAVMRMRPSLPLRLYSHTVHNHLTESVTAKSNMPTIYPFDTTMSKQTKVFNKVLVANRGEIACRIIKTCKKLGIKTVAVYSDLDAKALHVRLADEAVHLGPASSSESYLSIPRIMDAIKQTGANAVHPGYGFLSENPAFVKTLEEHQVVFIGPRASAIAAMGDKIQSKLIAKASGVHCIPGYDGEIYDVEEAVRLSREIGYPVMIKASAGGGGKGMRIAWNDTEVKEGFKLAKQESKSSFGDDRMLIEKYIDNPRHIEVQVLGDNYGHVVYLPERECSIQRRNQKVVEESPSVHLDPITRRKMGEQAVALAKHVGYNSAGTVEFLVDNDRNFYFLEMNTRLQVEHPITEYVTGLDLVEHMLYSAANRPLALQQDNIQLNGWAMEARVYAEDPKLYLPSVGRLLTYQEPHSVRCDSGFTEGSEMSVEYDPLICKLATYGSTRQEALQKMLGALDEYVIKGVTHNIPLLRAVFAHPRFQEGSRITTHFLAEEYPDGFRTHPLSQEQGNQLAAVTSALWLKKRQYEWQGKTPLPLTSLEDIWVHIVDEQSQHQFESHVRIQQKNFTEFEALTSSGLLEYSTEWPLHNLLAHTKIGNKQLVVQYLDTLTMGFRIQYQGNPYQVTLMSHDQHQLLKHMKAKSVAEQNKIVKSPMPGRIVSVAVKEGDEVPEGAELVVIEAMKMQNSLKTSHFGKVKKVYIYSGHTVKPGQTLIEFYDQSALVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NM04</accession>
    <name>A0A1C7NM04_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Origin recognition complex subunit 2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">orc2</name>
        <name evidence="9" type="ORF">A0J61_01772</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Component of the origin recognition complex (ORC).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 5">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the ORC2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000060">
        <property type="protein sequence ID" value="OBZ90183.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NM04"/>
    <dbReference type="FunCoup" id="A0A1C7NM04">
        <property type="interactions" value="1203"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NM04"/>
    <dbReference type="InParanoid" id="A0A1C7NM04"/>
    <dbReference type="OrthoDB" id="346673at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005664">
        <property type="term" value="C:nuclear origin of replication recognition complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003688">
        <property type="term" value="F:DNA replication origin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007220">
        <property type="entry name" value="ORC2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056772">
        <property type="entry name" value="RecA-like_ORC2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056773">
        <property type="entry name" value="WHD_ORC2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14052">
        <property type="entry name" value="ORIGIN RECOGNITION COMPLEX SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14052:SF0">
        <property type="entry name" value="ORIGIN RECOGNITION COMPLEX SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04084">
        <property type="entry name" value="RecA-like_ORC2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24882">
        <property type="entry name" value="WHD_ORC2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0235">DNA replication</keyword>
    <keyword evidence="4 5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Origin recognition complex subunit 2 RecA-like" evidence="7">
        <location>
            <begin position="261"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="domain" description="Origin recognition complex subunit 2 winged-helix" evidence="8">
        <location>
            <begin position="489"/>
            <end position="548"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="117"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="126"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="165"/>
            <end position="198"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007421"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU368084"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF04084"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF24882"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OBZ90183.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="560" mass="64459" checksum="182C9108505D0CE5" modified="2016-11-30" version="1">MRIHRQTDQEIPIHIVSKVDSGSAQSEYKLALEHHTGKKPKRREQTYDFGLTVTKQQQQHEPGSQPHQTEQDNTGEILSHFKPMDVDQEENNDDVSGRSMFRFQQSIKKNVNTLMNKTLEDDGQQKKKGRVKQTKKNQAQIAQVKTNHSKRRRIQKHLDSLRNDSEEEQDTSSSEDEEQQKETPIYDDNEEEEEEEEIGCGVRSKLQDTFDQVEGHERYFQSQTPSKTSDNTLARLPVLEPQEFHHLLEKTPKKHHEEFMILSEMHKQHFSQWCFELHSGFNLVFYGYGSKRTLLNEFAQEVLTDGPLVVVNGFFPSISIKDILVKITSGGALGAHFKAASTSSILDHVNAICDYFSNPDRDYQSLYLVIHNLDGPNLRNERTQTALSMLAHADNIHLIASVDHINAGLLWDNVKSSRFNWIWHDATTFADYLVETSFENSMMIRQGELGGARGAKYVLDSLTYNARGVFKVLAEYQLEAMDDCKMEGKGNESVGLTYSQYYQKCREGFYVSSDLSFRTELTEFRDHKLIFTKKNSDGTEFFFIPLDKTALTNLLEQINH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NMJ2</accession>
    <name>A0A1C7NMJ2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">DNA damage-binding protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">DDB1_1</name>
        <name evidence="6" type="ORF">A0J61_03472</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000150">
        <property type="protein sequence ID" value="OBZ88484.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NMJ2"/>
    <dbReference type="FunCoup" id="A0A1C7NMJ2">
        <property type="interactions" value="898"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NMJ2"/>
    <dbReference type="InParanoid" id="A0A1C7NMJ2"/>
    <dbReference type="OrthoDB" id="433457at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.910">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018846">
        <property type="entry name" value="Beta-prop_RSE1/DDB1/CPSF1_1st"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058543">
        <property type="entry name" value="Beta-prop_RSE1/DDB1/CPSF1_2nd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050358">
        <property type="entry name" value="RSE1/DDB1/CFT1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004871">
        <property type="entry name" value="RSE1/DDB1/CPSF1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10644">
        <property type="entry name" value="DNA REPAIR/RNA PROCESSING CPSF FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10433">
        <property type="entry name" value="Beta-prop_RSE1_1st"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23726">
        <property type="entry name" value="Beta-prop_RSE1_2nd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03178">
        <property type="entry name" value="CPSF_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RSE1/DDB1/CPSF1 first beta-propeller" evidence="4">
        <location>
            <begin position="15"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="domain" description="RSE1/DDB1/CPSF1 second beta-propeller" evidence="5">
        <location>
            <begin position="407"/>
            <end position="708"/>
        </location>
    </feature>
    <feature type="domain" description="RSE1/DDB1/CPSF1 C-terminal" evidence="3">
        <location>
            <begin position="764"/>
            <end position="1088"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF03178"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF10433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF23726"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OBZ88484.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="1123" mass="125446" checksum="BD9CBC7F95325AA4" modified="2016-11-30" version="1">MKKHHVVTTINPATAVTSAVKGRFIHASAENLLVSKGSTVEIYSILADGIKLSTEFSVYGVIDKLEICQIPDRDTCSVFILTDQKYFTIISYSARTETMITEGHGLLNEPRAKISDQATAVVTETKNNTLLVSAYTSYLFSIPLNRPDSSNPNSLKGKAKTSRFSASSIRTNEFDFLDMVALKGIQQSCIAALLGEINELKTIKIFRYDPQKSELVENEKLTVKVEATTHTLIPVPNPIGGLLAVGEYILSYHDLSTNSREPKELSIDPVTITSYVFLEGSCDSCLLGDSEGYLYFLRLETINMKVNNINSTMIGQIPVATCLVDLGNQLFFAGSTKADSCVFRLNRAPNGRLTIEILNYFYNLAPIVDFCLFDYDQQGKQTMICCSGVDRDGSLRIVENGVGFTEQYNLDIPLIKDIWTLTSSEQKSQDALLISTFDQSIFLKQKSPTEYTEYNIYASIDTKEITLASTVTHSGQLCQVTPSFVRLMEHAELGILLDEWKPPNGQQIAFARTDATHCIVCYGEGTLAYFEFEPKRLQPKSTRQLQDVVCIQLSLSVENGLGRDCVLIGSLQERKIYLVELPNLDATLLELNLDQDLAPTDMIMAHFGTASYLMILFGDGQLSSYVIEKKSHAFHVGQERQTMIGTYCTGMTLYQQNREYKVFIAGSRPTVVSHQHGALSFSAVNLKDVYRFNALHHDQAILMTQHGLLFGKIDDSQQLHHTKIKTHPNDMPTRIRYMPQLKLLAVGAIVISKNVNNNIMHQQGKLSILDAQTLQTLDSFSLERNEVVESMTISQFSGYRQEFLFVGTAIPDAEDGESSRGRILVFQVNEARQLELIESVNMPGVVYDLKPCQKSIVACVNGSVFCLSIFRPDLPAGTRIKFDLNVHRNVLALCMDVRDDQVLIGDLMRSVSVLSATQHDPLKLELRAMDSKPTWMTAVKFIDEHVYMGADDKSNLFTLTWDKHGVKNAHGISKLEVLGGFHLGSLVNCFREGTLMDTKSQVKKHIMTKLIDPSFTFATVHGSIGVVKTITTEAFELFQQLQEGILRENHNVGKLDYAAWRSYKPKISHLSDQQASCYLDGDVLKKFAEMSKHDKQKIVTGSSLLQSYDVKQIEDLVYDLVSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NMQ3</accession>
    <name>A0A1C7NMQ3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Histone-binding protein RBBP4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">Rbbp4_1</name>
        <name evidence="8" type="ORF">A0J61_01709</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000057">
        <property type="protein sequence ID" value="OBZ90240.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NMQ3"/>
    <dbReference type="FunCoup" id="A0A1C7NMQ3">
        <property type="interactions" value="919"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NMQ3"/>
    <dbReference type="InParanoid" id="A0A1C7NMQ3"/>
    <dbReference type="OrthoDB" id="427795at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006325">
        <property type="term" value="P:chromatin organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022052">
        <property type="entry name" value="Histone-bd_RBBP4-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050459">
        <property type="entry name" value="WD_repeat_RBAP46/RBAP48/MSI1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22850">
        <property type="entry name" value="WD40 REPEAT FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12265">
        <property type="entry name" value="CAF1C_H4-bd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 6" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="Histone-binding protein RBBP4-like N-terminal" evidence="7">
        <location>
            <begin position="13"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="195"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="239"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="283"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="340"/>
            <end position="382"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF12265"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OBZ90240.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="393" mass="45223" checksum="C31C6BC34586BB91" modified="2016-11-30" version="1">MTANDEEQKRIKEEYSEWKKTAPVLYDMVITHNLTWPTLTCQWLPKRTIVNGFVKQQLLIGTHTNDEENNYVQYLDIDIPEKGLDTPEEQKTKMYITQKIHHEGEVNKARYQPDQPDVFATKTRDGDVLVFDRTSSVEPLLRLKGHSMEGYGLAWNPHTTKKNHLLSAGFDHLICHWDIGCAAHQDRELQPLQRYEGHTNCVEDISWNSANDALFASVADDMKLMLWDSRDPVKPIQQVQAHQNEINSVAFHPHREWMLATGSSDKTVGLFDIRKLNQKLHSMETHEGEVTQVAWSPHDDPILASAGTDRRIVIWDLRRIGQEQTPEDAEDGPPEIMFVHSGHTSRISDFSWNPTDRWVLASVAEDNVAQIWQMSRNIYANTDSLQINLSQLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NMZ5</accession>
    <name>A0A1C7NMZ5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Palmitoyltransferase</fullName>
            <ecNumber evidence="10">2.3.1.225</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">PFA4_2</name>
        <name evidence="12" type="ORF">A0J61_02106</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>L-cysteinyl-[protein] + hexadecanoyl-CoA = S-hexadecanoyl-L-cysteinyl-[protein] + CoA</text>
            <dbReference type="Rhea" id="RHEA:36683"/>
            <dbReference type="Rhea" id="RHEA-COMP:10131"/>
            <dbReference type="Rhea" id="RHEA-COMP:11032"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57379"/>
            <dbReference type="ChEBI" id="CHEBI:74151"/>
            <dbReference type="EC" id="2.3.1.225"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="10">The DHHC domain is required for palmitoyltransferase activity.</text>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the DHHC palmitoyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.225" evidence="10"/>
    <dbReference type="EMBL" id="LUGH01000075">
        <property type="protein sequence ID" value="OBZ89846.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NMZ5"/>
    <dbReference type="STRING" id="101091.A0A1C7NMZ5"/>
    <dbReference type="InParanoid" id="A0A1C7NMZ5"/>
    <dbReference type="OrthoDB" id="331948at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019706">
        <property type="term" value="F:protein-cysteine S-palmitoyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001594">
        <property type="entry name" value="Palmitoyltrfase_DHHC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039859">
        <property type="entry name" value="PFA4/ZDH16/20/ERF2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026768">
        <property type="entry name" value="YPEH2ZP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12246">
        <property type="entry name" value="PALMITOYLTRANSFERASE ZDHHC16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01529">
        <property type="entry name" value="DHHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14976">
        <property type="entry name" value="YPEH2ZP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50216">
        <property type="entry name" value="DHHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 10" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="7" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="5 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0564">Palmitate</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 10 12" id="KW-0808">Transferase</keyword>
    <keyword evidence="3 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="45"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="139"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="180"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="domain" description="Palmitoyltransferase DHHC" evidence="11">
        <location>
            <begin position="91"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="12">
        <location>
            <position position="559"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00048048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU079119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF01529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="OBZ89846.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="559" mass="64065" checksum="A68EA61CBD0BDF60" modified="2016-11-30" version="1" fragment="single">MSCWKSIKGPLTVLLVVIVIIFICSTSQIFVLWPFFGLNSVHSRVILATLNFFVFMIFVNYYLTCATNPGIVPQRWLPRQQAYIEVKKSTHTPRFCKTCDNHKPPRAHHCSSCHRCVLKMDHHCPWVNNCVGFANYGHFFRLIIYVDISIVYLFVLLCYRLAYMIQEIHHVQQYPHLTEIVFLSINMLLVIIVMIGVGILTGYHLYCITSNTTTIEGWEKGRSLTIKGMGKIQNVKYPYHQGIFKNVQAVLGKCPLFWLVPQPMKGDGLNFPLNTKSMNECEALDEKDFSSRSALNRPTSVASQWTMTERFSLTESLNMKPLKAKTSMNTFASNASTLIDHRQSNVLAKRQSETSFIDFVSSNGNYLLLRSMEPTRVRLPRPRSNNSQEHNGRRVQLQRYTFPNITPPSMVQSQRRSTQLYAHHFQQQQQLIHASQMIGERTGLVTPVKPVYKLTCKHCTTTVCTRGMKAILLADTTIELYSTDTPSQNGNVIGYHVVSPCSHCLDACNNGHFWMFHSNACQPAERHDKDKKIMLWNNLPRAEMDTEFMMGSCIPYDQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NNV5</accession>
    <name>A0A1C7NNV5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Chromatin structure-remodeling complex subunit rsc9</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">rsc9_0</name>
        <name evidence="7" type="ORF">A0J61_01378</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000043">
        <property type="protein sequence ID" value="OBZ90559.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NNV5"/>
    <dbReference type="FunCoup" id="A0A1C7NNV5">
        <property type="interactions" value="8"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NNV5"/>
    <dbReference type="InParanoid" id="A0A1C7NNV5"/>
    <dbReference type="OrthoDB" id="338531at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016586">
        <property type="term" value="C:RSC-type complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006325">
        <property type="term" value="P:chromatin organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd16100">
        <property type="entry name" value="ARID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.60">
        <property type="entry name" value="ARID DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001606">
        <property type="entry name" value="ARID_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036431">
        <property type="entry name" value="ARID_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052406">
        <property type="entry name" value="Chromatin_Remodeling_Comp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048420">
        <property type="entry name" value="Zap1-like_Znf1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22970">
        <property type="entry name" value="AT-RICH INTERACTIVE DOMAIN-CONTAINING PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22970:SF14">
        <property type="entry name" value="AT-RICH INTERACTIVE DOMAIN-CONTAINING PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01388">
        <property type="entry name" value="ARID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21816">
        <property type="entry name" value="Zap1_zf1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01014">
        <property type="entry name" value="ARID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00501">
        <property type="entry name" value="BRIGHT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46774">
        <property type="entry name" value="ARID-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51011">
        <property type="entry name" value="ARID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="ARID" evidence="6">
        <location>
            <begin position="11"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="136"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="213"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="749"/>
            <end position="779"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="213"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="749"/>
            <end position="772"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OBZ90559.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="858" mass="95320" checksum="CC23ACF6F6DA91D2" modified="2016-11-30" version="1">MARLRDTIDRTPEYVNFIKELKQFHLEKGTTLQAEPVLGGRRLDLYKIFQVVANSGGFEEVTKNRGWKQVGDIFQFPSTCTNSAYILKGVYIRNLLGWEEEKLWKKNWKPPKELLGPNAHKSSTLAGKAYKSAIKKTSPTLKSSSQKPPKSTTKNKTASNASSNSQANSPTDVSPSSVDPLTVLQQLANPLLFNLNVDTSALAGNMPIDDTALAFSTAPPSPSLPASASSSPTPTPTPTDLSSPSNMLTEKDRILFALQFGQKADVEWALDEIVTISFEFPEKLDLGASPFLLQLLVFLAQPCLVTYVAENALPNNATDTLNSMMNQDTNNTLEKKDNLTGEKVNLCIPSAFISVTDSNNNHNQNGLDIILKVLHILRNFSFLNSHIPILAKHTMVKELLLQGLQASMSTGHVELGRHSIDVLENIAVQMELASSDDSCLQCIQTLVAAHDRYLVIGSIRTLTWLTMNENNHAYLIQCPVITRVSQMLLSNDEELVGTSLEYIYQHTRISHQSRSQFLASPDSNAYVGLLVSLLMTKSKYFCTRFVREDIALPTPNPTNNPEQPAVPRVPDLTEYQKLDEPFRCLGWLKDKFEVADRSSVLSLDDIYLLYEARFGLEKALKMRDFYTVMKIAFPKVCTSETKSLLGSPGHSAPVVEGLNVIGIQIKMSILQDRPQVPCKWSQCSLMFDDTFSLQRHVLHDHMTLDASDYVCSWSHCKNEQNVFETKDCWISHLRTHFYNQVGESCYNSPVQSPEPSLSSSPSTPASHISSTSMPSPKVKPVDMSDIQGIALVASHLLNWLSKDPQSAAYFIPYEKELTSIAEQRPKLAPSIWSICSNFKTSLKPSSPTLVHNDVSTTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NPA5</accession>
    <name>A0A1C7NPA5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_01029</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000028">
        <property type="protein sequence ID" value="OBZ90927.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NPA5"/>
    <dbReference type="InParanoid" id="A0A1C7NPA5"/>
    <dbReference type="OrthoDB" id="2264061at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ90927.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="363" mass="40860" checksum="A46FE37D931C8AA0" modified="2016-11-30" version="1">MSASPSFIKLWSSKLSDSINCLAVGKPFLEELSEENDILIGTTAGRVMILNQTKPVEGLLETKGGSIQSIQLHDLTGFGALDLAVGDCDGIVTLFSRQQILSKRDLGSAITDITIHHDLTGSCEIIAGDINGSLTSFQQHDALWKINIAEESAKLATLGSVGILTSHAYRCTMLIRYDRKDDNHLLYDIWIGYDLFTCMRRLAIGSFHTKWRENTIFAIAKRYQLSHFISEEGLKRFISNHPNKKIRKDSKKIDLRQVLFAGQDGFVYIMIDFEIFQWFYVGFCLTKIIQFRPSTLKTHESDIVLCTGHSNEVAIYQDGEKISSIKTSDWPHAITLGDVNADGKDELILGSLDQMIEVYEWRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NPI3</accession>
    <name>A0A1C7NPI3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_01146</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000033">
        <property type="protein sequence ID" value="OBZ90809.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NPI3"/>
    <dbReference type="InParanoid" id="A0A1C7NPI3"/>
    <dbReference type="OrthoDB" id="2262177at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="20"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="81"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="170"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="170"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="205"/>
            <end position="214"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ90809.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="214" mass="24300" checksum="36B1655D2468F65D" modified="2016-11-30" version="1">MRTEYGVHLMSKSLWSDRIASLINLFLCIAVAVYTSLKSGTIPWTGSVSSSFDSSMQGYVSYCSSYSDTVLSNRCWLTNGTWLGIIIVGFFWLILALYSFILKNSEIYDEDYDTYDFKQDVPMANTHPLMNQSSIQSTGGHYYVQPNPYMMSSGTHPTNNYYNPTYYPSPTSPVSATSPFSPEEGYQRPRRVSKTYLEEDNVTSETERHPPHSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NPQ0</accession>
    <name>A0A1C7NPQ0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Delta(12) fatty acid desaturase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">FAD12</name>
        <name evidence="3" type="ORF">A0J61_00857</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000022">
        <property type="protein sequence ID" value="OBZ91101.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NPQ0"/>
    <dbReference type="STRING" id="101091.A0A1C7NPQ0"/>
    <dbReference type="InParanoid" id="A0A1C7NPQ0"/>
    <dbReference type="OrthoDB" id="1461976at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03507">
        <property type="entry name" value="Delta12-FADS-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005804">
        <property type="entry name" value="FA_desaturase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012171">
        <property type="entry name" value="Fatty_acid_desaturase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32100">
        <property type="entry name" value="OMEGA-6 FATTY ACID DESATURASE, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00487">
        <property type="entry name" value="FA_desaturase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="59"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="82"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="235"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="269"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="domain" description="Fatty acid desaturase" evidence="2">
        <location>
            <begin position="88"/>
            <end position="360"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ91101.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="392" mass="45304" checksum="91618DEB3AFDA3B7" modified="2016-11-30" version="1">MATQRNVKSDSAAQNAVKPVIDEAIERNWEIPEFTIKEIRDAIPAHCFRRDTFTSFTHVLHDFAIVGFLAYLASYIDTIPNVYARIALWPMYWIAQGIVGTGVWVLGHECGHQAFSPSKTINNSVGFVLHTLLLVPYHSWRFSHSRHHKATGHMSKDQVFLPKTRNKIGLPARDQDPQADGPHDVLEETPIASLWRMFLMFTFGWPLYLFTNVTGQDYPGWASHFNPTCDIYEEGQYWDVMTSTAGIIAMIGFLTYCGQIFGSLTMIKFYVIPYLNVNFWLVLITYLQHTDPKLPHYRENVWNFQRGAALTVDRSYGAIINYFHHHISDTHVAHHFFSTMPFYHAQEATLHIKKALGKHYNCDNTPIPIALWRVWKECRFVEDEGDVVFYKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NQ66</accession>
    <name>A0A1C7NQ66_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 14">Dolichyl-phosphate-mannose--protein mannosyltransferase</fullName>
            <ecNumber evidence="4 14">2.4.1.109</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="primary">PMT4_1</name>
        <name evidence="16" type="ORF">A0J61_00822</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="14">Transfers mannose from Dol-P-mannose to Ser or Thr residues on proteins.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13 14">
            <text>a di-trans,poly-cis-dolichyl beta-D-mannosyl phosphate + L-seryl-[protein] = 3-O-(alpha-D-mannosyl)-L-seryl-[protein] + a di-trans,poly-cis-dolichyl phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17377"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:13546"/>
            <dbReference type="Rhea" id="RHEA-COMP:19498"/>
            <dbReference type="Rhea" id="RHEA-COMP:19501"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:57683"/>
            <dbReference type="ChEBI" id="CHEBI:58211"/>
            <dbReference type="ChEBI" id="CHEBI:137321"/>
            <dbReference type="EC" id="2.4.1.109"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12 14">
            <text>a di-trans,poly-cis-dolichyl beta-D-mannosyl phosphate + L-threonyl-[protein] = 3-O-(alpha-D-mannosyl)-L-threonyl-[protein] + a di-trans,poly-cis-dolichyl phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:53396"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:13547"/>
            <dbReference type="Rhea" id="RHEA-COMP:19498"/>
            <dbReference type="Rhea" id="RHEA-COMP:19501"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:57683"/>
            <dbReference type="ChEBI" id="CHEBI:58211"/>
            <dbReference type="ChEBI" id="CHEBI:137323"/>
            <dbReference type="EC" id="2.4.1.109"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 14">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 14">Endoplasmic reticulum membrane</location>
            <topology evidence="1 14">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 14">Belongs to the glycosyltransferase 39 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.109" evidence="4 14"/>
    <dbReference type="EMBL" id="LUGH01000021">
        <property type="protein sequence ID" value="OBZ91120.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NQ66"/>
    <dbReference type="FunCoup" id="A0A1C7NQ66">
        <property type="interactions" value="241"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NQ66"/>
    <dbReference type="InParanoid" id="A0A1C7NQ66"/>
    <dbReference type="OrthoDB" id="292747at2759"/>
    <dbReference type="UniPathway" id="UPA00378"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004169">
        <property type="term" value="F:dolichyl-phosphate-mannose-protein mannosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd23285">
        <property type="entry name" value="beta-trefoil_MIR_PMT4-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.80.10.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003342">
        <property type="entry name" value="ArnT-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036300">
        <property type="entry name" value="MIR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016093">
        <property type="entry name" value="MIR_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027005">
        <property type="entry name" value="PMT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032421">
        <property type="entry name" value="PMT_4TMC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10050">
        <property type="entry name" value="DOLICHYL-PHOSPHATE-MANNOSE--PROTEIN MANNOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10050:SF51">
        <property type="entry name" value="PROTEIN O-MANNOSYL-TRANSFERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02815">
        <property type="entry name" value="MIR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02366">
        <property type="entry name" value="PMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16192">
        <property type="entry name" value="PMT_4TMC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00472">
        <property type="entry name" value="MIR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82109">
        <property type="entry name" value="MIR domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50919">
        <property type="entry name" value="MIR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 14" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="5 14 16" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="11 14" id="KW-0472">Membrane</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0677">Repeat</keyword>
    <keyword evidence="6 14 16" id="KW-0808">Transferase</keyword>
    <keyword evidence="7 14" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10 14" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="131"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="156"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="181"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="212"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="235"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="274"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="591"/>
            <end position="612"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="633"/>
            <end position="655"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="667"/>
            <end position="689"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="709"/>
            <end position="728"/>
        </location>
    </feature>
    <feature type="domain" description="MIR" evidence="15">
        <location>
            <begin position="322"/>
            <end position="382"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00045085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00045102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU367007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="OBZ91120.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="756" mass="87044" checksum="1631929961BB9E80" modified="2016-11-30" version="1">MSAHLRQRRVEPDEASEKLLHVDFDDSKKYGKDFVPVQRYQNAHRITLLILTILDAFVTFYKIWNPEEVVFDEVHFGKFAGYYLKRTYYFDVHPPLAKLMIAGAGYLLGFDGQYDFANIGDNYIDHQVPYIGLRALPATLNVICTMLIYGIMQESGYSLAICVLSTVMYIFDNAIVTQNRLILLDSMLLVFMLATIYCYIRFRQLRHKSFSVEWWSWLVVTGIFMAFTFSVKMVGLFLVALIGIAVICDLWNLLDIRRGLTMSQFMKHFYARAFALIIVPIFVYLFWFYVHFAILNESGPGDNFMSARFQDTLKNSPLKMAALEIHYGDEITLKNKDTNAYLHSHDLHYPLRYEDGRVSSKGQQVTGVMESNENCFWRIKPSGEDLSLEDKEGNARPVKHGDVIQLEHVVTRTNLLTHDVASPWMPTNEEITTVPLDTRYEETLFQVLFEDDDDDNAVLETHMTPFRLIHEDTKVAVWVHNKKLPEWGLGHLEVNGNKNAVEKTNYWVAQEIKGKNATEINAQKNQKELGHMPFIKKFLELQSRMISHNAGLTKPHPYQSTPITWPFMIRGVSYWSRESDRSQIYLTGNIFGWYLSVGGIAVFTGILLADVLARRRGVEPIEEPVRHRIIQSAGFFCVAWALHYFPFFLMGRSLFLHHYLPAASLNYLLLGAMYQFIFVDGIDSPVSFLSRQSKLTRQTSMKADVSWKVYAAVGITILLQLAVFVYLAPLTYGTPMTLEQVQSHQLLNGWKLQYAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NQ68</accession>
    <name>A0A1C7NQ68_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_02535</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000097">
        <property type="protein sequence ID" value="OBZ89404.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NQ68"/>
    <dbReference type="STRING" id="101091.A0A1C7NQ68"/>
    <dbReference type="InParanoid" id="A0A1C7NQ68"/>
    <dbReference type="OrthoDB" id="2289155at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ89404.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="95" mass="10687" checksum="3781C53A5A1A8117" modified="2016-11-30" version="1">MAYISELSGLGFWTPSCHCDALHWTSEKPVNIPASALNWESCCKHGAVKIDALRDPPQLLKDLFTDNLIWHLLLLRLDATQSLQQVDQALVHLHS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NQA5</accession>
    <name>A0A1C7NQA5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">PXMP2/4 family protein 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">A0J61_01322</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the peroxisomal membrane protein PXMP2/4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000040">
        <property type="protein sequence ID" value="OBZ90626.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NQA5"/>
    <dbReference type="STRING" id="101091.A0A1C7NQA5"/>
    <dbReference type="InParanoid" id="A0A1C7NQA5"/>
    <dbReference type="OrthoDB" id="860at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005778">
        <property type="term" value="C:peroxisomal membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007248">
        <property type="entry name" value="Mpv17_PMP22"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11266:SF93">
        <property type="entry name" value="INTEGRAL MEMBRANE PROTEIN 25D9-6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11266">
        <property type="entry name" value="PEROXISOMAL MEMBRANE PROTEIN 2, PXMP2 MPV17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04117">
        <property type="entry name" value="Mpv17_PMP22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="54"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="93"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="160"/>
            <end position="178"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU363053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OBZ90626.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="193" mass="21448" checksum="2E54184DC9CDCD42" modified="2016-11-30" version="1">MATPVESKTFLAWYLTQLASHPLRTKACTSGVLSGLQELTAQKLSGAKELDKRVLQMAAYGLFISGPLNHLMYEIMNKIFAGKEGARVKIGQLLFSNLVISPVMNSVYLTAMAILAGVRSPVQLKANLKRGLLPMQKVSWAVSPLTIIFAQKFLPPTTWVPFFNLVAFVFGTYINTMVKRKRIKEAEEAEKKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NQQ8</accession>
    <name>A0A1C7NQQ8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DNA-directed RNA polymerases I and III subunit RPAC2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">rpc19</name>
        <name evidence="9" type="ORF">A0J61_00572</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the archaeal Rpo11/eukaryotic RPB11/RPC19 RNA polymerase subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000013">
        <property type="protein sequence ID" value="OBZ91368.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NQQ8"/>
    <dbReference type="FunCoup" id="A0A1C7NQQ8">
        <property type="interactions" value="246"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NQQ8"/>
    <dbReference type="InParanoid" id="A0A1C7NQQ8"/>
    <dbReference type="OrthoDB" id="510325at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055029">
        <property type="term" value="C:nuclear DNA-directed RNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005736">
        <property type="term" value="C:RNA polymerase I complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005666">
        <property type="term" value="C:RNA polymerase III complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003899">
        <property type="term" value="F:DNA-directed RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006363">
        <property type="term" value="P:termination of RNA polymerase I transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006386">
        <property type="term" value="P:termination of RNA polymerase III transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006362">
        <property type="term" value="P:transcription elongation by RNA polymerase I"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006361">
        <property type="term" value="P:transcription initiation at RNA polymerase I promoter"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006384">
        <property type="term" value="P:transcription initiation at RNA polymerase III promoter"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042797">
        <property type="term" value="P:tRNA transcription by RNA polymerase III"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd07029">
        <property type="entry name" value="RNAP_I_III_AC19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1360.10:FF:000006">
        <property type="entry name" value="DNA-directed RNA polymerases I and III subunit RPAC2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1360.10">
        <property type="entry name" value="RNA polymerase, RBP11-like subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00261">
        <property type="entry name" value="RNApol_arch_Rpo11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036603">
        <property type="entry name" value="RBP11-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009025">
        <property type="entry name" value="RBP11-like_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008193">
        <property type="entry name" value="RNA_pol_Rpb11_13-16kDa_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033898">
        <property type="entry name" value="RNAP_AC19"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022905">
        <property type="entry name" value="Rpo11-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13946">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE I,II,III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13946:SF28">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASES I AND III SUBUNIT RPAC2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13656">
        <property type="entry name" value="RNA_pol_L_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55257">
        <property type="entry name" value="RBP11-like subunits of RNA polymerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01154">
        <property type="entry name" value="RNA_POL_L_13KD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 9" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <feature type="domain" description="DNA-directed RNA polymerase RBP11-like dimerisation" evidence="8">
        <location>
            <begin position="65"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="16"/>
            <end position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022079"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00025751"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF13656"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OBZ91368.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="156" mass="17600" checksum="A3C24646087ACDD2" modified="2016-11-30" version="1">MAPAKKEEKNTSATVEQEEQMEVDEHSEVEEHEEENSDEDMEEEPDMVVSADKIEIVGSHSDPTAMTFCFKQEDHTLGNALRHVVNKNPHVDFCGYSIPHPSEAKMNVRIQTTDKTTAIDALKSGLSNLYDMVAHVRETYAAELAKKEYVEFDEVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NR62</accession>
    <name>A0A1C7NR62_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Signaling protein YkoW</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">ykoW</name>
        <name evidence="4" type="ORF">A0J61_00305</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000006">
        <property type="protein sequence ID" value="OBZ91635.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NR62"/>
    <dbReference type="STRING" id="101091.A0A1C7NR62"/>
    <dbReference type="InParanoid" id="A0A1C7NR62"/>
    <dbReference type="OrthoDB" id="264015at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005330">
        <property type="entry name" value="MHYT_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35152">
        <property type="entry name" value="DOMAIN SIGNALLING PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_5G11310)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35152:SF1">
        <property type="entry name" value="DOMAIN SIGNALLING PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_5G11310)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03707">
        <property type="entry name" value="MHYT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50924">
        <property type="entry name" value="MHYT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="47"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="88"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="123"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="153"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="187"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="228"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="domain" description="MHYT" evidence="3">
        <location>
            <begin position="12"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="421"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="501"/>
            <end position="523"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="894"/>
            <end position="919"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="501"/>
            <end position="517"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="896"/>
            <end position="906"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50924"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OBZ91635.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="957" mass="107488" checksum="040A8D2B54332040" modified="2016-11-30" version="1">MSTFGQEAERSFNGGIIFVSYLISAAGALTTLELLTRRTHIRGLYNWFLLASAAFTMGAVGIWSMHFIGNNSLTLILDDKTYQLSYQAGYTFASLVVSFVCMFLAFTFVGITEEVKLARIIPSGIFTGLGVACMHYMGQFAIEYFVIGYKIGYVVGAIIIACAAATIALYIFFKLREQWADQWWKRVGCAMILALAVCGMHYTALVGTEFHKPMNNAMIPVPKLQTPALIGIISAIIVSACIALLFISIKTGIKHLPMYTKKDKNKRLILDSVIFDPLGHVLVNTDGTLPMTEVVHNLELNETQKEFNANHPLFHRLFQTSIIKASFRFYEDTQPSALSMCSTTELYDNINTSFVDSIRTLRNELRFTELGDLGVLSDIVVTTDIISKSNKLFGKGSSFKSTKKAEQGSIRMFFMDNEETVSKDKHNSLPSTLGKETILQDSKDNNSTTKTNRKSFFWCPKNSKSEGLADEEKAISTHSFNLSNRLSSSTNVAAINDCTTAPSLSHQQTEEATSTKPRLSVEDSDGEDKHIFMIRKLTDEAEVTRLLSQGYRFTEPVFISKIMAAKLRIPIDHMRHYFVDMLQMANSVCGLTQPNWRPTETETSPNLAVFKAPTQSTVYVGAFILLDESKDLNGVQLLVDKSKRFAFPMVQLTMNQTVPTKLDHDQLDFISSLHDRSLFDIAELSKLMHHKDFQGRRVASITDDFIQGLERTAQHLLETTSYSKALYRNTKLHATVLDLTPFALTTGPCQLIVFRSFINTPGAIAAVNHTFSEPIKCMPLDVYKHFCNYVTEQAVNIYQDHIRATESPSFVIQQQIYRPQTLQNPVHINKDSHATTPTDDVIKITYPATKSAEVVDNDTKTDMDIHLDILKKQVQPIYTPPTSPVTDAFSLLPPPRAKRNRHKHKNSVSSIRGEPKATSERKALQILKPVPLSVLPVYDRFWWFNSLVEETIHHSVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NR94</accession>
    <name>A0A1C7NR94_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Tyrosine specific protein phosphatases domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_00995</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000027">
        <property type="protein sequence ID" value="OBZ90946.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NR94"/>
    <dbReference type="STRING" id="101091.A0A1C7NR94"/>
    <dbReference type="InParanoid" id="A0A1C7NR94"/>
    <dbReference type="OrthoDB" id="9988524at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004721">
        <property type="term" value="F:phosphoprotein phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.190.10">
        <property type="entry name" value="Protein tyrosine phosphatase superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029021">
        <property type="entry name" value="Prot-tyrosine_phosphatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026893">
        <property type="entry name" value="Tyr/Ser_Pase_IphP-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016130">
        <property type="entry name" value="Tyr_Pase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000387">
        <property type="entry name" value="Tyr_Pase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31126:SF1">
        <property type="entry name" value="TYROSINE SPECIFIC PROTEIN PHOSPHATASES DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31126">
        <property type="entry name" value="TYROSINE-PROTEIN PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13350">
        <property type="entry name" value="Y_phosphatase3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52799">
        <property type="entry name" value="(Phosphotyrosine protein) phosphatases II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00383">
        <property type="entry name" value="TYR_PHOSPHATASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50056">
        <property type="entry name" value="TYR_PHOSPHATASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tyrosine specific protein phosphatases" evidence="1">
        <location>
            <begin position="397"/>
            <end position="432"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ90946.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="542" mass="61187" checksum="17CFF566281F1620" modified="2016-11-30" version="1">MTLNIHNQQGEVIVGFLNKKTDNNRLVLLVHGDQGHKDSFYQAQLAERLPINSFRFDLHGRGQSEGCADYGDIAKDVDDIHAVARYFEVQGYEIYAVIAYGRGSLSGLKYATSCDKPLSHYVNIGTPYANKNTKLGLDENHVSKPITSLACTHLPCTLKEWKIYQNNQWTSIKVTEEQIQAFDSWDNTHVIRMPKTTCVHTIHGINDQVVSAHHAAMFANTISSHTLTLVPDADHQFTDKEDCLIETIVGYFETHAKDAFTKAVLMGQHVSVCIPRWIDVPGVKNFRDIGGWPLKDGSGYIRERIVFRCGHLVGITQQGIDTLHRLNVIAAFDFRSDPEIEKQGDMPRIEGLTRYPSAMFTKADYSPAALASRWKGYFEGAKGFPKVYSVILEKGGSQYSNIFKHLIQNHSTTSTKSIIVHCTAGKDRTGIFGMLLLGLCGVDEDIIAHEYALSNLGYWEPEHELEKKAKMLGATLDDVRMVMSAPYLAMKETIQLVKDKYGSIEDYVRNECKLTTEEIEKVKHLMIVPIRFEERQLFRPRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NRF5</accession>
    <name>A0A1C7NRF5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Conserved oligomeric Golgi complex subunit 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">Cog1_1</name>
        <name evidence="8" type="ORF">A0J61_00272</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Golgi apparatus membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the COG1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000005">
        <property type="protein sequence ID" value="OBZ91683.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NRF5"/>
    <dbReference type="InParanoid" id="A0A1C7NRF5"/>
    <dbReference type="OrthoDB" id="46189at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017119">
        <property type="term" value="C:Golgi transport complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006891">
        <property type="term" value="P:intra-Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033370">
        <property type="entry name" value="COG1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31658">
        <property type="entry name" value="CONSERVED OLIGOMERIC GOLGI COMPLEX SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31658:SF0">
        <property type="entry name" value="CONSERVED OLIGOMERIC GOLGI COMPLEX SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08700">
        <property type="entry name" value="VPS51_Exo84_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0653">Protein transport</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004395"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006653"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00020978"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OBZ91683.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="717" mass="82753" checksum="A3FD8E727819AF7C" modified="2016-11-30" version="1">MTSEDDPDSYLIESSVPDVRAFEQKTRNAIETQKKELRAMVGDKYQDLISAADTIITMSKNAQAIQTNFERMQSTYDVESIKQNAKEQVKLQDGKSNHSALVKSLADVPEQIWHAMENHQYLHASRLFVLAQQVHTYLEEEKEKAIIDIDLAFPVIQRQWDAVSAFKMQIVQRSVHYLSVSKQLPENMAEIMIGLMLLDNMSYTDVLKKLLEIRLNLIKDIIECYMKSSDSLVHRLAHQLKEVALVFKTTVVQIVSIFVLLEDDRQKPMIESYVNSFKQTFLIPSSRNAETSISQSAITRLFSPSSNIHLIVRFLPESIQQYLPQFDPSTMPSIEDIRQSIDGWISSVEQYLHHHLDERLQAVDKHSDLVQIRTKIWEALREDEIAKDKKNKWRTANQAVLTSSYSVWNNLYRDSFNRHTKRLIDNSLKQLINQPGSTIWNSLVDPKTLKPQKDLSVTMHVWPDLNSKHQAAFVLPNLSSAQEIRSFKTSLTETVYDRTSSLSLLQNEFDMILSDITKDAKSYLMNGSNMNDECFHVKNDTNMIKNYFEDKCFETIQSYSREVNILLKRIAGWTDYETANGASIFLGRLVRNICLLSKELPNALSISIDTPPTFELRSRIDQNPKYSQAQKILTDTFHDSHNIWLDYLQKKYAEDLKKTLLSTKWNDQCPAQLVWDHVEADIKLPVQSTNSIARGLYNVCEELQRFNSTLLDKVSXK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NS18</accession>
    <name>A0A1C7NS18_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Myb-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">A0J61_00137</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the MT-A70-like family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000003">
        <property type="protein sequence ID" value="OBZ91818.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NS18"/>
    <dbReference type="STRING" id="101091.A0A1C7NS18"/>
    <dbReference type="InParanoid" id="A0A1C7NS18"/>
    <dbReference type="OrthoDB" id="6781668at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007757">
        <property type="entry name" value="MT-A70-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001005">
        <property type="entry name" value="SANT/Myb"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05063">
        <property type="entry name" value="MT-A70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51143">
        <property type="entry name" value="MT_A70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50090">
        <property type="entry name" value="MYB_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Myb-like" evidence="3">
        <location>
            <begin position="102"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="224"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00489"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OBZ91818.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="623" mass="72234" checksum="6A0B6ED79A427396" modified="2016-11-30" version="1" fragment="single">DDEEIDELESSDDAMDLDNDFMDVATNSTIKEESFEVKLEHIESEASADRRPKSTSSSLLDESEEDIFTRENIEKWQAARIRAWSCRHTVPDCYYFRLLLPGETKRNGPWSSEEHEAFMKRYKEWISNGYRLGSFWGIFSLAIPHRVGYQCMGYYRRLLASGKLKDDSYAFENGKLKLVGKRQPYETKTLSVEGLGSEWETEKVKELEKKVDALIQEFHGTHLQGATSKRTSKPAPKVKSTTSKQTAQIGKLIRRMASSPLASSPSVSRLESEPEIADLRRENWKKEWYDRLTEYKEFLEPYLDKDVKMAHWHAKQEWRRGLTTTEMLLRKDMTIKPAFSLIANHAPEAPRIQQTSLSRFFTGVKKPKIDTPDDLISYTRIPGELYSGVKQIKPLSRIVQSDPFKTLYFELNQIDDATTLLNGICRSTTNPFIQSSIECVLADPPWEFYVADGKNDGQCSLNLEQFRSIMEKTVRHMSAGMIFVWTHKLIQADVVRTMYEIDCKYVENLVWFKKSVNNVHLDDPSPFFSSTKEILLMFKKGDGFEMRHQRSPDVIIDFEKPRQEWIEDEFTEPKPTAVYEMIETLLPKAGYDPSINRGRLLELWAKKKGPRREGWIAFHVNKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NSU4</accession>
    <name>A0A1C7NSU4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 10">Mitogen-activated protein kinase</fullName>
            <ecNumber evidence="2 10">2.7.11.24</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">HOG1_1</name>
        <name evidence="12" type="ORF">A0J61_00198</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.24"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 10">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="activity regulation">
        <text evidence="10">Activated by threonine and tyrosine phosphorylation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.24" evidence="2 10"/>
    <dbReference type="EMBL" id="LUGH01000004">
        <property type="protein sequence ID" value="OBZ91756.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NSU4"/>
    <dbReference type="FunCoup" id="A0A1C7NSU4">
        <property type="interactions" value="573"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NSU4"/>
    <dbReference type="InParanoid" id="A0A1C7NSU4"/>
    <dbReference type="OrthoDB" id="192887at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004707">
        <property type="term" value="F:MAP kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051403">
        <property type="term" value="P:stress-activated MAPK cascade"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07856">
        <property type="entry name" value="STKc_Sty1_Hog1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000049">
        <property type="entry name" value="Mitogen-activated protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000050">
        <property type="entry name" value="Mitogen-activated protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003527">
        <property type="entry name" value="MAP_kinase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050117">
        <property type="entry name" value="MAPK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008352">
        <property type="entry name" value="MAPK_HOG-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038783">
        <property type="entry name" value="MAPK_Sty1/HOG1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24055">
        <property type="entry name" value="MITOGEN-ACTIVATED PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01773">
        <property type="entry name" value="P38MAPKINASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01351">
        <property type="entry name" value="MAPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 10 12" id="KW-0418">Kinase</keyword>
    <keyword evidence="10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5 8 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 9" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="4 10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="11">
        <location>
            <begin position="20"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="50"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012411"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU000304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU361165"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="OBZ91756.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="384" mass="43596" checksum="601B4CF10B12A9DD" modified="2016-11-30" version="1">MAEFVKLSIFGTVFEVTTRYVDLQPVGMGAFGLVCSSKDQLTGMNVAIKKIMKPFSAPVLAKRTYRELKLLKALRHENIISLSDIFISPLEDIYFVTELLGTDLHRLLQSRPLEKQFIQYFLYQILRGLKYVHSAGVIHRDLKPSNILINENCDLKICDFGLARVQETQMTGYVSTRYYRAPEIMLTWQKYDVAVDIWSAGCIFAEMLEGKPLFPGKDHVHQFSIIIELLGSPNEDVVSTICSESTLRFVKNLPKREPVPFSQRFAGQDPEAIDLLEKMLQFDPRKRINAEEALAHPYLAPYHDPTDEPVAPEKFDWSFNEADLPIDTWKVMMYSEILDFHNVDNVDGSQFLGTPLAGPTMENPDGATLDGNMLSTNASFQSQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MTB1</accession>
    <name>A0A1C7MTB1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Core-binding (CB) domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_11826</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01002543">
        <property type="protein sequence ID" value="OBZ80125.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MTB1"/>
    <dbReference type="InParanoid" id="A0A1C7MTB1"/>
    <dbReference type="OrthoDB" id="2289843at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47823">
        <property type="entry name" value="lambda integrase-like, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="14"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="187"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ80125.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="187" mass="21573" checksum="460AF2D7DDF4ACF6" modified="2016-11-30" version="1" fragment="single">PTHSGNREHRCRRTQQTNDKSTIRSNYSKTNIQSHSEQLETTKRRRICSETESKTTNILEFQSGSKLSSDRRLSTVMEESGLVVLPHSFDHTALDTSTLVADLNEDEENSEAIHISAQSMDYDRMAVIRHKKQEEGLSRESIEYLTKANRESTNANYDLSWRKFVEWCERQTSPIDPTEYDTVTALN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MTJ5</accession>
    <name>A0A1C7MTJ5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Histone H2B</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">HTB1_0</name>
        <name evidence="14" type="ORF">A0J61_11746</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.</text>
    </comment>
    <comment type="subunit">
        <text evidence="11">The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Chromosome</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2 11">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 11">Belongs to the histone H2B family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01002424">
        <property type="protein sequence ID" value="OBZ80205.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MTJ5"/>
    <dbReference type="FunCoup" id="A0A1C7MTJ5">
        <property type="interactions" value="254"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7MTJ5"/>
    <dbReference type="InParanoid" id="A0A1C7MTJ5"/>
    <dbReference type="OrthoDB" id="10254238at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000786">
        <property type="term" value="C:nucleosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046982">
        <property type="term" value="F:protein heterodimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030527">
        <property type="term" value="F:structural constituent of chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd22910">
        <property type="entry name" value="HFD_H2B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.20.10:FF:000014">
        <property type="entry name" value="Histone H2B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.20.10">
        <property type="entry name" value="Histone, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007125">
        <property type="entry name" value="H2A/H2B/H3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009072">
        <property type="entry name" value="Histone-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000558">
        <property type="entry name" value="Histone_H2B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055333">
        <property type="entry name" value="HISTONE_H2B_site"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23428">
        <property type="entry name" value="HISTONE H2B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00125">
        <property type="entry name" value="Histone"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00621">
        <property type="entry name" value="HISTONEH2B"/>
    </dbReference>
    <dbReference type="SMART" id="SM00427">
        <property type="entry name" value="H2B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47113">
        <property type="entry name" value="Histone-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00357">
        <property type="entry name" value="HISTONE_H2B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 11" id="KW-0158">Chromosome</keyword>
    <keyword evidence="8 11" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1017">Isopeptide bond</keyword>
    <keyword evidence="10 11" id="KW-0544">Nucleosome core</keyword>
    <keyword evidence="9 11" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0832">Ubl conjugation</keyword>
    <feature type="domain" description="Core Histone H2A/H2B/H3" evidence="13">
        <location>
            <begin position="21"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00006846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022499"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022843"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023269"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU000451"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF00125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="OBZ80205.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="119" mass="12975" checksum="1F109B1B5943E7E5" modified="2016-11-30" version="1">MAPKETAAGKAPAKVKSADGKKKKVSRRETYSSYIYKVLKQVHPDTGISNKAMSILNSFVNDIFERIASEASKLAAYNKRSTISSREIQTAVRLILPGELAKHAVSEGTKAVTKYTSSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MTP2</accession>
    <name>A0A1C7MTP2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Protein AF-9 homolog</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">Yeats2</name>
        <name evidence="3" type="synonym">YAF9</name>
        <name evidence="6" type="ORF">A0J61_11763</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Component of the SWR1 complex which mediates the ATP-dependent exchange of histone H2A for an H2A variant leading to transcriptional regulation of selected genes by chromatin remodeling. Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histones H4 and H2A. The NuA4 complex is also involved in DNA repair. Yaf9 may also be required for viability in conditions in which the structural integrity of the spindle is compromised.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Component of the SWR1 chromatin-remodeling complex and of the NuA4 histone acetyltransferase complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Nucleus</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="3">The coiled-coil domain is required for assembly into the NuA4 complex.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the YAF9 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01002450">
        <property type="protein sequence ID" value="OBZ80188.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MTP2"/>
    <dbReference type="STRING" id="101091.A0A1C7MTP2"/>
    <dbReference type="InParanoid" id="A0A1C7MTP2"/>
    <dbReference type="OrthoDB" id="1741717at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000812">
        <property type="term" value="C:Swr1 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006325">
        <property type="term" value="P:chromatin organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd16907">
        <property type="entry name" value="YEATS_YEATS2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1970">
        <property type="entry name" value="YEATS domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038704">
        <property type="entry name" value="YEAST_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005033">
        <property type="entry name" value="YEATS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055127">
        <property type="entry name" value="YEATS2_3HBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055129">
        <property type="entry name" value="YEATS_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23195">
        <property type="entry name" value="YEATS DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22951">
        <property type="entry name" value="3HBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03366">
        <property type="entry name" value="YEATS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51037">
        <property type="entry name" value="YEATS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0010">Activator</keyword>
    <keyword evidence="3" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3" id="KW-0227">DNA damage</keyword>
    <keyword evidence="3" id="KW-0234">DNA repair</keyword>
    <keyword evidence="1 2 3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="YEATS" evidence="5">
        <location>
            <begin position="57"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="190"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="209"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="350"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00376"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU367117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51037"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OBZ80188.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="350" mass="39963" checksum="1791DB768A93A424" modified="2016-11-30" version="1" fragment="single">EEEKDKPNDPSIETNLPEPIENATAQKQVEEEEEEQTEQPKVESLAAAVSSADTADIGSRFYIKRHIIVGNVSKFIIPERRDPSLKQFTHKWMIYVVEPPQSKESISAFITCVRFYLHPSYKPNDVVDVTEPPFKLTRLGWGEFPVRIQLFFVDKRRNKAVDLIHHLKLDNSHSGRQLLGGERSIEIELDRNTDFKDTNTIPSAVADTPQEPTSNQEEQPPPPSQEEQVQSMAAKQKMSLLNGMLKESVQKLPIIRAGSHGTVLPYTCASSPIMFFKWSVGKRKALEWQRARLLRLQVQSKAFEVNDNVLRTAAELLSTKDVLLWCREHKYTPSRLEDVEEKKSALIMGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MU08</accession>
    <name>A0A1C7MU08_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Transcription activator GCR1-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_11704</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01002368">
        <property type="protein sequence ID" value="OBZ80247.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MU08"/>
    <dbReference type="InParanoid" id="A0A1C7MU08"/>
    <dbReference type="OrthoDB" id="428577at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0060963">
        <property type="term" value="P:positive regulation of ribosomal protein gene transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052146">
        <property type="entry name" value="HOT1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022210">
        <property type="entry name" value="TF_GCR1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37784">
        <property type="entry name" value="PROTEIN MSN1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37784:SF4">
        <property type="entry name" value="TRANSCRIPTION FACTOR-LIKE PROTEIN EUC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12550">
        <property type="entry name" value="GCR1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Transcription activator GCR1-like" evidence="1">
        <location>
            <begin position="2"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12550"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ80247.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="71" mass="8411" checksum="29FAFC2D23FE97A8" modified="2016-11-30" version="1" fragment="single">IPSINELNRLYKASWRRDEKGRKMYSRRITIINKIRQLVSEGMTEEDAVKQLEAKRLSEKLSLNKLHDALK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MU19</accession>
    <name>A0A1C7MU19_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_11629</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01002276">
        <property type="protein sequence ID" value="OBZ80322.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MU19"/>
    <dbReference type="InParanoid" id="A0A1C7MU19"/>
    <dbReference type="OrthoDB" id="2289822at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ80322.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="93" mass="10756" checksum="66B29AA816FB0FAA" modified="2016-11-30" version="1" fragment="single">MSNTPFRLMLRYQQNVSDCITEQAASIPSIFEGSFKPFIKPAHKIRGVDWSLFLQFIVPTLVAEQIEFQEHESRRQGRSKPDEEVKAVLDALY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-06-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MU67</accession>
    <name>A0A1C7MU67_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_11561</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01002195">
        <property type="protein sequence ID" value="OBZ80390.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MU67"/>
    <dbReference type="InParanoid" id="A0A1C7MU67"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ80390.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="85" mass="9987" checksum="E6AB2364D6560676" modified="2016-11-30" version="1">MLDYLTGTFDSILQFVGNQHMLYYIESFNSFRQLQDSGVTFEILLFTMESIISVFFGVCFPHTVEYIEEDGIERFYMPVYEPSKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MV81</accession>
    <name>A0A1C7MV81_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Tubulin-folding cofactor B</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">Tbcb</name>
        <name evidence="7" type="ORF">A0J61_11592</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the TBCB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01002231">
        <property type="protein sequence ID" value="OBZ80359.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MV81"/>
    <dbReference type="FunCoup" id="A0A1C7MV81">
        <property type="interactions" value="392"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7MV81"/>
    <dbReference type="InParanoid" id="A0A1C7MV81"/>
    <dbReference type="OrthoDB" id="2130750at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005938">
        <property type="term" value="C:cell cortex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035371">
        <property type="term" value="C:microtubule plus-end"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043014">
        <property type="term" value="F:alpha-tubulin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051010">
        <property type="term" value="F:microtubule plus-end binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031122">
        <property type="term" value="P:cytoplasmic microtubule organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007023">
        <property type="term" value="P:post-chaperonin tubulin folding pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007021">
        <property type="term" value="P:tubulin complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01789">
        <property type="entry name" value="Ubl_TBCB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.30.190:FF:000013">
        <property type="entry name" value="Tubulin-folding cofactor B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.190">
        <property type="entry name" value="CAP Gly-rich-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036859">
        <property type="entry name" value="CAP-Gly_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000938">
        <property type="entry name" value="CAP-Gly_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045172">
        <property type="entry name" value="TBCB_Ubl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000626">
        <property type="entry name" value="Ubiquitin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18916">
        <property type="entry name" value="DYNACTIN 1-RELATED MICROTUBULE-BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18916:SF85">
        <property type="entry name" value="TUBULIN-FOLDING COFACTOR B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01302">
        <property type="entry name" value="CAP_GLY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14560">
        <property type="entry name" value="Ubiquitin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01052">
        <property type="entry name" value="CAP_GLY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74924">
        <property type="entry name" value="Cap-Gly domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00845">
        <property type="entry name" value="CAP_GLY_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50245">
        <property type="entry name" value="CAP_GLY_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50053">
        <property type="entry name" value="UBIQUITIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0143">Chaperone</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ubiquitin-like" evidence="5">
        <location>
            <begin position="4"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="domain" description="CAP-Gly" evidence="6">
        <location>
            <begin position="173"/>
            <end position="215"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00025779"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OBZ80359.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="238" mass="27299" checksum="F814F875B43BCA08" modified="2016-11-30" version="1">MSIVTLFVDTSEEQVSSERRFDKSLTISQLKYKIEPITGIPYSTQKIDLYHGKHLLGTLDDESRMLGSYPVEDYMRLHVIDTNPHRIKNQYTDVSLVEKFELTDDQYEKRTDTVRAFKERNKLGRFSDEAAAKEEAIEKAFKEAANQIKIGDRCQVLSDDDSVRRLGIVRFVGETQFQSGLWVGVQYDEPLGKNDGSVQGQQYFSCPPKYGGFVRPTKVVVGDFPEEDLFTDDELEEM</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MVT7</accession>
    <name>A0A1C7MVT7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">ATP-dependent DNA helicase</fullName>
            <ecNumber evidence="9">5.6.2.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">pif1_16</name>
        <name evidence="12" type="ORF">A0J61_11392</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="5.6.2.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="9">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the helicase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.6.2.3" evidence="9"/>
    <dbReference type="EMBL" id="LUGH01001983">
        <property type="protein sequence ID" value="OBZ80559.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7MVT7"/>
    <dbReference type="InParanoid" id="A0A1C7MVT7"/>
    <dbReference type="OrthoDB" id="2325450at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043139">
        <property type="term" value="F:5'-3' DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000723">
        <property type="term" value="P:telomere maintenance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010285">
        <property type="entry name" value="DNA_helicase_pif1-like_DEAD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049163">
        <property type="entry name" value="Pif1-like_2B_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051055">
        <property type="entry name" value="PIF1_helicase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47642">
        <property type="entry name" value="ATP-DEPENDENT DNA HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47642:SF5">
        <property type="entry name" value="ATP-DEPENDENT DNA HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05970">
        <property type="entry name" value="PIF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21530">
        <property type="entry name" value="Pif1_2B_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 9" id="KW-0227">DNA damage</keyword>
    <keyword evidence="9" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="7 9" id="KW-0234">DNA repair</keyword>
    <keyword evidence="6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4 9 12" id="KW-0347">Helicase</keyword>
    <keyword evidence="3 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-0413">Isomerase</keyword>
    <keyword evidence="1 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA helicase Pif1-like DEAD-box helicase" evidence="10">
        <location>
            <begin position="51"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="domain" description="DNA helicase Pif1-like 2B" evidence="11">
        <location>
            <begin position="295"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="12">
        <location>
            <position position="350"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU363044"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF05970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF21530"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="OBZ80559.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="350" mass="40115" checksum="189EA22BC5E97632" modified="2016-11-30" version="1" fragment="single">MIYPDYYEHLINLQEGGIQXNRQVNIESLDDINDQXRGIEVYQLLEERKINSVAFVSGAASTGKSFILRMLERHYKIEGYKVFKLAPTGVAAYNISXQTLHRFFGLTNFALVPNLALLNQYVKLYPKMILLIDEYSMISSKMLESINEALTKVTNRNTNMGGIRTIFFGRIAQLLPVKANEGKIWKSPIYNTVNRYQLRIPVRQNDAHFVSILNKIKPYKFDQSVIEFINSRTVAKSELPSRCLRLYTTLERVTAANERDYNSFPGEGKVYEAQDNFIGNAGTARATLNETRLLQRLPLKEKMPVMLIQNLNVQGGWVNGTIAQTEYLEDDNICLRKTSNNSNSVQIYWI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-06-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MVZ2</accession>
    <name>A0A1C7MVZ2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_11345</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001930">
        <property type="protein sequence ID" value="OBZ80606.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MVZ2"/>
    <dbReference type="InParanoid" id="A0A1C7MVZ2"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="16"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ80606.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="16" mass="1870" checksum="66B17AEB640B3A18" modified="2016-11-30" version="1" fragment="single">MPSLIRRLLITLELDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MVZ3</accession>
    <name>A0A1C7MVZ3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_10941</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001527">
        <property type="protein sequence ID" value="OBZ81010.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MVZ3"/>
    <dbReference type="STRING" id="101091.A0A1C7MVZ3"/>
    <dbReference type="InParanoid" id="A0A1C7MVZ3"/>
    <dbReference type="OrthoDB" id="2289822at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ81010.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="605" mass="69447" checksum="66943865C3862F4A" modified="2016-11-30" version="1">MNIHPLHRHNKRRHHMYSPLQFNFRTKDEYKIQIAVCPGKPKDLVSFSQPVIAEVNTLHEKGLVIKKQGVERFTGNVAILSVTGDITGIAVLISFAGHTHTYECQICSVKAREPAPDCIHGKYFPFVGDERTIESLKEGDIAKGMKGVSELLTFLPTFMGTFSFFRDELHMIGHGLGHLVYNLLDPKANGHLKVKSSLEYSFDFDQPGCFQDLIDWIAFSKPTNPTAFNFSFQHKKGSLGAADWQFFLLHIVPTMIIPHLKYPSAKKALLSPVNACSISLQRSITEGELEDMKRFFTMWATFLKAEIADRRLMVRVWTMNNHFASYHIYELIKRYGPLRYYSCRSLERTIQKYTNLSRSRSAPDVETNNLLERFSYFKTYNSYLNLRGLITARRTRADEYEDHPDDVEGVMPQSWKKFEKAVLIDDLEIASVSMVRIRQAMERYLTRLHGGPSLLDNSEVKWAARAVIDGVVIQSRWHRGNQKNVKRVNNLVILEAKESSRSRTMSWFVGVVITFIVHVNRGTVHHLAAVSLVKNSAMCNFGIPIIEIFANNEDRKVIICDVSDIIILAGFVRYNDNDCQYKVIWKNALYYKKSDGRSCGRRRDM</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MX98</accession>
    <name>A0A1C7MX98_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Glycerol-3-phosphate dehydrogenase [NAD(+)]</fullName>
            <ecNumber evidence="9">1.1.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">gpd1</name>
        <name evidence="12" type="ORF">A0J61_10560</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="4 9">
            <text>sn-glycerol 3-phosphate + NAD(+) = dihydroxyacetone phosphate + NADH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:11092"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57597"/>
            <dbReference type="ChEBI" id="CHEBI:57642"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.1.1.8"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 8">Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.8" evidence="9"/>
    <dbReference type="EMBL" id="LUGH01001235">
        <property type="protein sequence ID" value="OBZ81391.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MX98"/>
    <dbReference type="FunCoup" id="A0A1C7MX98">
        <property type="interactions" value="387"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7MX98"/>
    <dbReference type="InParanoid" id="A0A1C7MX98"/>
    <dbReference type="OrthoDB" id="10263760at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0141152">
        <property type="term" value="F:glycerol-3-phosphate dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042803">
        <property type="term" value="F:protein homodimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046168">
        <property type="term" value="P:glycerol-3-phosphate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1040.10:FF:000004">
        <property type="entry name" value="Glycerol-3-phosphate dehydrogenase [NAD(+)]"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000365">
        <property type="entry name" value="Glycerol-3-phosphate dehydrogenase [NAD(+)]"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1040.10">
        <property type="entry name" value="N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008927">
        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013328">
        <property type="entry name" value="6PGD_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006168">
        <property type="entry name" value="G3P_DH_NAD-dep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006109">
        <property type="entry name" value="G3P_DH_NAD-dep_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017751">
        <property type="entry name" value="G3P_DH_NAD-dep_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011128">
        <property type="entry name" value="G3P_DH_NAD-dep_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR03376">
        <property type="entry name" value="glycerol3P_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11728">
        <property type="entry name" value="GLYCEROL-3-PHOSPHATE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11728:SF8">
        <property type="entry name" value="GLYCEROL-3-PHOSPHATE DEHYDROGENASE [NAD(+)]-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07479">
        <property type="entry name" value="NAD_Gly3P_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01210">
        <property type="entry name" value="NAD_Gly3P_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000114">
        <property type="entry name" value="Glycerol-3-P_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00077">
        <property type="entry name" value="GPDHDRGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48179">
        <property type="entry name" value="6-phosphogluconate dehydrogenase C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00957">
        <property type="entry name" value="NAD_G3PDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7 8" id="KW-0520">NAD</keyword>
    <keyword evidence="2 8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glycerol-3-phosphate dehydrogenase NAD-dependent N-terminal" evidence="10">
        <location>
            <begin position="9"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="domain" description="Glycerol-3-phosphate dehydrogenase NAD-dependent C-terminal" evidence="11">
        <location>
            <begin position="198"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="5">
        <location>
            <position position="209"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="13"/>
            <end position="18"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="101"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="125"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="158"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="273"/>
            <end position="274"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="273"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="300"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="302"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011009"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00048683"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR000114-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR000114-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR000114-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU361243"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF01210"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF07479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="OBZ81391.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="352" mass="39085" checksum="EB02A875948CA979" modified="2016-11-30" version="1">MSTHQKQRITIIGSGNWGSAIARVCAANARKFSDTFEPEVRMWVYEEQIDGQNLTDIINQKHENVKYLPGIHLGDNVKAIPDVKEAAKDTNILVFVLPHQFVYGVCETLCDVIPKENCRAISLIKGLDYRDENLLIFSEEIEKILGIHCAALSGANIASEVAEEQFGEATIACRESSDGDLFLKLFHTDYFDITVIGDWRGLQVCGALKNVVALGAGISEGLKYGNNTRAAVIRRGLVEMRKFGKSFFGGVHTETFFESCGVADLITSCSGGRNKKVAAAFVQSDKSIEEIEKEMLNGQKLQGTTTSQEVFNFLKARDMLDEFPLLTTVYRIIYEKEPAESIALCLRTHKLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MX99</accession>
    <name>A0A1C7MX99_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_10520</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001214">
        <property type="protein sequence ID" value="OBZ81430.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MX99"/>
    <dbReference type="InParanoid" id="A0A1C7MX99"/>
    <dbReference type="OrthoDB" id="2286148at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="120"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="130"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="173"/>
            <end position="185"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ81430.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="185" mass="20443" checksum="0A103B2A1BF1F545" modified="2016-11-30" version="1">MPEAKRHMNNSQAKEDATLKHIQYLLSGTFRPLDILASEICTNDLQNDHSQRFIAIINELSSAILNVNASISSFRKDIAFRAFNPNFRAPSEGNQNCLMSSEAFQSAVNQQATANKTIIEASSRGKHGGDQSTSHTNIGKNNPFFRSGPPIDQGGYPAGHQSYIRPQQHHQGDSAQQKQQQQLVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MXP3</accession>
    <name>A0A1C7MXP3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Glycogen [starch] synthase</fullName>
            <ecNumber evidence="8">2.4.1.11</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">gsy-1_0</name>
        <name evidence="9" type="ORF">A0J61_10361</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Glycogen synthase participates in the glycogen biosynthetic process along with glycogenin and glycogen branching enzyme. Extends the primer composed of a few glucose units formed by glycogenin by adding new glucose units to it. In this context, glycogen synthase transfers the glycosyl residue from UDP-Glc to the non-reducing end of alpha-1,4-glucan.</text>
    </comment>
    <comment type="function">
        <text evidence="8">Transfers the glycosyl residue from UDP-Glc to the non-reducing end of alpha-1,4-glucan.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>[(1-&gt;4)-alpha-D-glucosyl](n) + UDP-alpha-D-glucose = [(1-&gt;4)-alpha-D-glucosyl](n+1) + UDP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:18549"/>
            <dbReference type="Rhea" id="RHEA-COMP:9584"/>
            <dbReference type="Rhea" id="RHEA-COMP:9587"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15444"/>
            <dbReference type="ChEBI" id="CHEBI:58223"/>
            <dbReference type="ChEBI" id="CHEBI:58885"/>
            <dbReference type="EC" id="2.4.1.11"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="7">
            <dbReference type="Rhea" id="RHEA:18550"/>
        </physiologicalReaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 8">Glycan biosynthesis; glycogen biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the glycosyltransferase 3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.11" evidence="8"/>
    <dbReference type="EMBL" id="LUGH01001136">
        <property type="protein sequence ID" value="OBZ81590.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MXP3"/>
    <dbReference type="STRING" id="101091.A0A1C7MXP3"/>
    <dbReference type="InParanoid" id="A0A1C7MXP3"/>
    <dbReference type="OrthoDB" id="6335297at2759"/>
    <dbReference type="UniPathway" id="UPA00164"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004373">
        <property type="term" value="F:alpha-1,4-glucan glucosyltransferase (UDP-glucose donor) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005978">
        <property type="term" value="P:glycogen biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.2000:FF:000014">
        <property type="entry name" value="Glycogen [starch] synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.2000:FF:000045">
        <property type="entry name" value="Glycogen [starch] synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.260.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2000">
        <property type="entry name" value="Glycogen Phosphorylase B"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008631">
        <property type="entry name" value="Glycogen_synth"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10176:SF3">
        <property type="entry name" value="GLYCOGEN [STARCH] SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10176">
        <property type="entry name" value="GLYCOGEN SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05693">
        <property type="entry name" value="Glycogen_syn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53756">
        <property type="entry name" value="UDP-Glycosyltransferase/glycogen phosphorylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8" id="KW-0320">Glycogen biosynthesis</keyword>
    <keyword evidence="3 8" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010686"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00043883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU363104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OBZ81590.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="705" mass="81332" checksum="B829D48ED2EC5F92" modified="2016-11-30" version="1">MSTRRDVYNPLLFEVAWEVANKVGGIYTVIKTKVPVTVREFGDRYCLIGPLSYKTAPMEVESLELPPGEIRDTLEVMSSQGIRYLFGRWLVEGAPYVLLFDTGSASHKLDEWKADLWRSAGIPSPPNDHETNEAILFGYLVTWFLEEISRRYKDKSTESDLSPAIIAHFHEWQAGVPLPLIKQRKLDVTTIFTTHATLLGRYLCAGSVDFYNNLRNFDVDHEAGKRGIYHRYCIERGAAHCSDVFTTVSHITAYESEHLLKRKPDGVLPNGLNVVKFQAVHEFQNKHALNKEKINDFVRGHFYGHYDFDLENTVYFFTAGRYEFRNKGVDMFVEALGRLNDRMKAAKSNTTVVAFIVMPAATHSFNVEALKGQAVTKQLRETVNEIQSRVGRRIYEKALRGEELDPADFLHGEDKVLLKRRVFALKNNSLPPIVTHNMVDDGTDPIINQLRRLQLYNKPEDRVKCIFHPEFLNANNPLLSLDYEDFVRGCHLGVFPSYYEPWGYTPAECTVMGVPSITTNLSGFGCFMDENIENCEDYGIYIVDRRLKSVEESIQQLCEQMFRFCQKTRRQRINQRNRTERLSDLLDWKRMGLEYIKARQLALRRVYPDSFVDDDDQIDMESTVKKIPKPLSAPASPRIRHLVNGYFNEEEEEEEEESLIPLAKKEFPALHKKGDGTSREEELLREGDIMTLNKLTLEEKQHKHH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MXZ8</accession>
    <name>A0A1C7MXZ8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_10228</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001079">
        <property type="protein sequence ID" value="OBZ81727.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MXZ8"/>
    <dbReference type="STRING" id="101091.A0A1C7MXZ8"/>
    <dbReference type="InParanoid" id="A0A1C7MXZ8"/>
    <dbReference type="OrthoDB" id="10634383at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="107"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="297"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ81727.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="297" mass="33247" checksum="D72031F0B7E37993" modified="2016-11-30" version="1" fragment="single">MIRKYVNGALHRWDDFVNAALWAARIRTHTTTGYSPFFLTYVVQCFPKYRTYQLLTLAGEPLQSLAHVDRLRMVNAHMSSTPWYDPAAARQQWRNMKKHMMISQWNALLLLLYKSTLTLIFPINPLYLLVIQLFPKVIPDTIDPIDQMVSTPDSMTTSVSVPLPLTVTVPVFAPSLPILPSLNLTGPLIPSNTDIHFGSTLSDDLPVSTSSDDNNSTTRPPEVIDELIVTRLVVEDLTAEESLQNLLPDDDEFVDAIDDLPSALSVSESLTDADFFFDVDIDEVDSPSNQLNPSNTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MYD4</accession>
    <name>A0A1C7MYD4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Pseudouridine synthase</fullName>
            <ecNumber evidence="3">5.4.99.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">A0J61_10130</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Responsible for synthesis of pseudouridine from uracil.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>a uridine in RNA = a pseudouridine in RNA</text>
            <dbReference type="Rhea" id="RHEA:48348"/>
            <dbReference type="Rhea" id="RHEA-COMP:12068"/>
            <dbReference type="Rhea" id="RHEA-COMP:12069"/>
            <dbReference type="ChEBI" id="CHEBI:65314"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the pseudouridine synthase RluA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.4.99.-" evidence="3"/>
    <dbReference type="EMBL" id="LUGH01001045">
        <property type="protein sequence ID" value="OBZ81822.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MYD4"/>
    <dbReference type="FunCoup" id="A0A1C7MYD4">
        <property type="interactions" value="336"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7MYD4"/>
    <dbReference type="InParanoid" id="A0A1C7MYD4"/>
    <dbReference type="OrthoDB" id="424794at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009982">
        <property type="term" value="F:pseudouridine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000455">
        <property type="term" value="P:enzyme-directed rRNA pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02557">
        <property type="entry name" value="PseudoU_synth_ScRIB2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2350.10">
        <property type="entry name" value="Pseudouridine synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020103">
        <property type="entry name" value="PsdUridine_synth_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006224">
        <property type="entry name" value="PsdUridine_synth_RluA-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006225">
        <property type="entry name" value="PsdUridine_synth_RluC/D"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006145">
        <property type="entry name" value="PsdUridine_synth_RsuA/RluA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050188">
        <property type="entry name" value="RluA_PseudoU_synthase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00005">
        <property type="entry name" value="rluA_subfam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21600">
        <property type="entry name" value="MITOCHONDRIAL RNA PSEUDOURIDINE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21600:SF40">
        <property type="entry name" value="PSEUDOURIDYLATE SYNTHASE RPUSD2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00849">
        <property type="entry name" value="PseudoU_synth_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55120">
        <property type="entry name" value="Pseudouridine synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01129">
        <property type="entry name" value="PSI_RLU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50889">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0413">Isomerase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="Pseudouridine synthase RsuA/RluA-like" evidence="5">
        <location>
            <begin position="179"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="31"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="active site" evidence="1">
        <location>
            <position position="222"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR606225-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00182"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU362028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OBZ81822.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="454" mass="53170" checksum="E9822F543DA760D0" modified="2016-11-30" version="1">MSLEEHKRDLDRKELEVAEQPQKKKSKKKETKQEKAERKRLMAETNPYYQLAKTKEIPPEKRLTRRKEDDFRDIDDMDTAHYFFEDEMRKVKPYYFEYKSYAKGRWLGRSILEVFASEFRDRSEEYYRYAIERGLLTINDQQVTTDTIIKTSDVIGHKIHRHEPPCTDQPIKVVYEDDDLFVVDKPGGIPVHPAGRYRHNTIIHVLKKERNLTKLFPANRLDLPTSGLMLIARNSARAKQLEQEMSAGNIRKEYVCRVDGRFPDGEIVCDAPIKCISHKMSVNYVHEDGKPSVTKFERLSYNGKTSVVRCKPMTGRTHQIRVHLRYLGYPISNDPLYGSGTSWAPFIRPGERMEDKDARLLVDKLFEYSPMEEWDESGQPVLSPALVDQDNTRCSECSASLVLGKNYDQLCIFLHAWRYAADGWSYETELPFWAKEDFNDDQVPLKYRNTFIDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MYH6</accession>
    <name>A0A1C7MYH6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">A0J61_10145</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001050">
        <property type="protein sequence ID" value="OBZ81808.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MYH6"/>
    <dbReference type="STRING" id="101091.A0A1C7MYH6"/>
    <dbReference type="InParanoid" id="A0A1C7MYH6"/>
    <dbReference type="OrthoDB" id="5575144at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050335">
        <property type="entry name" value="ERT1_acuK_gluconeogen_tf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47659:SF7">
        <property type="entry name" value="FUNGAL TRANSCRIPTIONAL REGULATORY PROTEIN, N-TERMINAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47659">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="4">
        <location>
            <begin position="72"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="108"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="200"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="108"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="123"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="211"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="233"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="280"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="330"/>
            <end position="353"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OBZ81808.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="360" mass="39981" checksum="4D061FFFD8649D10" modified="2016-11-30" version="1">MQSIPPYYQQQQQGYQPQPYQPQPPAPNVLNNGPSLLNHPNGLPPMQHPGIPDQSQVPTGQPAPKRKQVKNACTNCQKACKKCDDARPCPRCIKYGIADTCVNSVRKERKKGIKRGPYKRRQKTGEEKPRKNAAELNTADQQPTQYAPVRGPTMTYGYPSNLNQYGQPFEMSYSQYYQKEHMMSQPYVVNPVYPPMGYPVIVSGGDGQPGQPGQPGQPQQHAYHPQYSTMIHQQQQQQQQQQQQQQQAQTPQQTSASSSPRPPMMHNEHVMHQSSPAGSPQVYYQQAVAAHVAQPQSTPQQHSQPPSQRNSPHLPEIKADHPSNEGFAKPQSMTPVPSTSTSTATTSSPDSGSWVPPRSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MZ39</accession>
    <name>A0A1C7MZ39_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Amino-acid permease BAT1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">BAT1_3</name>
        <name evidence="7" type="ORF">A0J61_09925</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000973">
        <property type="protein sequence ID" value="OBZ82028.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MZ39"/>
    <dbReference type="STRING" id="101091.A0A1C7MZ39"/>
    <dbReference type="InParanoid" id="A0A1C7MZ39"/>
    <dbReference type="OrthoDB" id="10054429at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006865">
        <property type="term" value="P:amino acid transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1740.10">
        <property type="entry name" value="Amino acid/polyamine transporter I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002293">
        <property type="entry name" value="AA/rel_permease1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004840">
        <property type="entry name" value="Amino_acid_permease_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45649">
        <property type="entry name" value="AMINO-ACID PERMEASE BAT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45649:SF26">
        <property type="entry name" value="OS04G0435100 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13520">
        <property type="entry name" value="AA_permease_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006060">
        <property type="entry name" value="AA_transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00218">
        <property type="entry name" value="AMINO_ACID_PERMEASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="26"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="63"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="112"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="155"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="186"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="225"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="279"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="384"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="408"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="447"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="479"/>
            <end position="500"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OBZ82028.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="516" mass="58071" checksum="F1D107E65D9411FB" modified="2016-11-30" version="1">MKKGPIYHYGSVATDIEQTQVLQRRFSTFATFGLAFSNIGILSNTSATFQTVFERGGPVVMLLSWNLVAFFMFCVACALAELCSLYPKSGGLYYWVFEMLDQHPTTKPRAPLIAFITGWMYAIANVISIGATNVTVALSLSSIFKLLFHVDLDRMYLMMITLCITWIHACLNVYQIHLLSLLNQWNVISSCLGLLVIVLILSWMVPHQEASWVFLHYENQTGFDHPGYVFMLGMIGAAYSLLGKIDTKSLLFDTQHEKGCECSAAMNEETKEADKSSSIAMVSSIAVSWLVGFIFLLALLFSIQDIDKIIHSTLAMPVAQLFYDAIGRQGTLMFLMLMMFCQFCTGATTTTVTSRQIYALARDHAIPMHSELDKISSRKLPENAVWCTMLLTFLVILPYPLSDHVFETIVSATTITIHFSYAMVLGCRLFYITTIGHDQGRFHLGKYSLWVTWIGFLWTCFAVFAFTLPANWPIVANTLNYAGMAWICTLSITCLTWLLWGQFIYHGPRAMHDGIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MZH6</accession>
    <name>A0A1C7MZH6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">NADH dehydrogenase (Ubiquinone) complex I, assembly factor 6</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">NDUFAF6</name>
        <name evidence="1" type="ORF">A0J61_09677</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000907">
        <property type="protein sequence ID" value="OBZ82270.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MZH6"/>
    <dbReference type="STRING" id="101091.A0A1C7MZH6"/>
    <dbReference type="InParanoid" id="A0A1C7MZH6"/>
    <dbReference type="OrthoDB" id="270318at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.600.10">
        <property type="entry name" value="Farnesyl Diphosphate Synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008949">
        <property type="entry name" value="Isoprenoid_synthase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002060">
        <property type="entry name" value="Squ/phyt_synthse"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00494">
        <property type="entry name" value="SQS_PSY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48576">
        <property type="entry name" value="Terpenoid synthases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0830">Ubiquinone</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ82270.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="310" mass="35430" checksum="B0DE81977B05868E" modified="2016-11-30" version="1">MVSTICLKSRAAFHLIARTSSRQYSTASSERVESALNYCRDLVRKRDYEGYLSTPFFPAHLRDTQYALRAFNVELASIRENVSKPEIGKMRMQFWKDALDKIYAGHPPEQPIALAIAEALRSSKLSAMWMKRIISERMSNLDDHQFMTIKDMEAYAENTQSSLLYLQLESLGIKDVNADHAISHIGKMIGISIFLRSLPFHISQKRLVLPAEITAKYNIVQENVFRGEAEGMEDAIYDVATAAYDQLLTARSIMNQIPADAFPAFLSAVPHIKFLENLEKTNFNIYDAKLQKKDWKLPITMYKAYKTQTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-06-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MZN3</accession>
    <name>A0A1C7MZN3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_09718</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000919">
        <property type="protein sequence ID" value="OBZ82232.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MZN3"/>
    <dbReference type="InParanoid" id="A0A1C7MZN3"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ82232.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="92" mass="10460" checksum="82B9CAF4C64DCB6A" modified="2016-11-30" version="1">MLATQSIDTYYTNDYCEHSNPIQNLVQPSPSKGRCYNGSKNPVVMLPFSLDVEHSPYSILHQASIVHTIYSIFNDFIIPFALHRAPRFVQSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MZY7</accession>
    <name>A0A1C7MZY7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">Acap2</name>
        <name evidence="4" type="ORF">A0J61_09566</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000880">
        <property type="protein sequence ID" value="OBZ82383.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MZY7"/>
    <dbReference type="STRING" id="101091.A0A1C7MZY7"/>
    <dbReference type="InParanoid" id="A0A1C7MZY7"/>
    <dbReference type="OrthoDB" id="10266696at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.60">
        <property type="entry name" value="Arfaptin homology (AH) domain/BAR domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045258">
        <property type="entry name" value="ACAP1/2/3-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027267">
        <property type="entry name" value="AH/BAR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004148">
        <property type="entry name" value="BAR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001849">
        <property type="entry name" value="PH_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23180:SF160">
        <property type="entry name" value="ADP-RIBOSYLATION FACTOR GTPASE-ACTIVATING PROTEIN EFFECTOR PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23180">
        <property type="entry name" value="CENTAURIN/ARF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16746">
        <property type="entry name" value="BAR_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103657">
        <property type="entry name" value="BAR/IMD domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50003">
        <property type="entry name" value="PH_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="PH" evidence="3">
        <location>
            <begin position="262"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="316"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OBZ82383.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="316" mass="37131" checksum="CB143BD631CCE7A8" modified="2016-11-30" version="1" fragment="single">MPALDIRGCLEDSPTFRKRIQSHEESIHNFENSLKALIKLTRSQVDLSIAYSHQQTELAREFMDFAHAQDDPIVAQALEKFGKSVVEVEKSRHMFVMDTFISPLDHFLKNTIMPIKELRKRFEKSSDEVDSALSRYMSKKPKDPTLQESAKELADTRKIFHKSYMEYVSQLNDIEAKKKVDYMENVLAYMYTESAFHHQSYEILKDLEPYMRDLTGLLHDSRQRYEEEVEEGLMYQQTCGQNASDQYNPMQQPYTPVEVIPKAHKSGYLFERKNGRVYQSWLRKYFSIYDDELISTTRGSKISTKEEDGTHVYNLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N075</accession>
    <name>A0A1C7N075_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_09497</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000863">
        <property type="protein sequence ID" value="OBZ82452.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N075"/>
    <dbReference type="InParanoid" id="A0A1C7N075"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="17"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="43"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="67"/>
            <end position="84"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ82452.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="84" mass="9141" checksum="0F9B8043DD04349E" modified="2016-11-30" version="1">MRGDILIEIALLQPLPITKPKETSSAARTSSYKRRAPTGKPHSATSLKETASQSDLLASESAKDMDDDHDGIELDVEGIDDEFQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N0G1</accession>
    <name>A0A1C7N0G1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Leukocyte receptor cluster member 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">LENG1</name>
        <name evidence="4" type="ORF">A0J61_09462</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000856">
        <property type="protein sequence ID" value="OBZ82488.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N0G1"/>
    <dbReference type="STRING" id="101091.A0A1C7N0G1"/>
    <dbReference type="InParanoid" id="A0A1C7N0G1"/>
    <dbReference type="OrthoDB" id="2159131at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019339">
        <property type="entry name" value="CIR_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039875">
        <property type="entry name" value="LENG1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22093">
        <property type="entry name" value="LEUKOCYTE RECEPTOR CLUSTER LRC MEMBER 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22093:SF0">
        <property type="entry name" value="LEUKOCYTE RECEPTOR CLUSTER MEMBER 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10197">
        <property type="entry name" value="Cir_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01083">
        <property type="entry name" value="Cir_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0675">Receptor</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CBF1-interacting co-repressor CIR N-terminal" evidence="3">
        <location>
            <begin position="8"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="79"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="207"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="17"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="82"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="120"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="164"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="174"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="244"/>
            <end position="253"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM01083"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OBZ82488.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="253" mass="30654" checksum="13DBB06455EF3B6C" modified="2016-11-30" version="1">MNILHHKSWHVYNKDNVERVRQDEAKAEEEAKKKQEKVILAESEARLDLLRKRANAHLPAEQQQTVIQHVNLFQDLQENSTNDEHEAEKKAQQDKQDRQLTMYLDKGASKEDQPWYTRSKQSDEKYRDQYKFKSKQDKKEDQKYKRKRESIRLIEDPLEYISKSQKKKHKEDRKKRSEGKSKEKEKTLTMDELRAKRLERERAEQARLKSLFLDDQQEPDVLDDRKRSYNSQFNRDETFEANQKNKRSSRYRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N0I5</accession>
    <name>A0A1C7N0I5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">TECPR1-like DysF domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">A0J61_11077</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001652">
        <property type="protein sequence ID" value="OBZ80874.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N0I5"/>
    <dbReference type="STRING" id="101091.A0A1C7N0I5"/>
    <dbReference type="InParanoid" id="A0A1C7N0I5"/>
    <dbReference type="OrthoDB" id="5586090at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005778">
        <property type="term" value="C:peroxisomal membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007031">
        <property type="term" value="P:peroxisome organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052646">
        <property type="entry name" value="Peroxisomal_PEX28-32"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010482">
        <property type="entry name" value="TECPR1-like_DysF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31679">
        <property type="entry name" value="PEROXISOMAL MEMBRANE PROTEIN PEX30-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31679:SF2">
        <property type="entry name" value="PEROXISOMAL MEMBRANE PROTEIN PEX30-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06398">
        <property type="entry name" value="Pex24p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="TECPR1-like DysF" evidence="5">
        <location>
            <begin position="8"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="158"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004308"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF06398"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OBZ80874.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="158" mass="19485" checksum="D6EE3F653A4D179E" modified="2016-11-30" version="1" fragment="single">MKLQFFTLIATYSNELWLLLRSNETIKDTLLLKKDPIDCTKAEDRKIYCFQIQQHQRWWFLIGWTDILLSQDPPEWADVYSRPTPSTNKFCLPPSTYDFCKQQDITKWHWIDPEWTVAENRWQYADWHWDKWSTIPSNNSFTRKRMWYRRAERIEKTQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N0K9</accession>
    <name>A0A1C7N0K9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Proteasome subunit beta</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">psmB6</name>
        <name evidence="11" type="ORF">A0J61_09389</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Cleavage of peptide bonds with very broad specificity.</text>
            <dbReference type="EC" id="3.4.25.1"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="10">Component of the proteasome complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="10">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the peptidase T1B family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000839">
        <property type="protein sequence ID" value="OBZ82561.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N0K9"/>
    <dbReference type="FunCoup" id="A0A1C7N0K9">
        <property type="interactions" value="498"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N0K9"/>
    <dbReference type="InParanoid" id="A0A1C7N0K9"/>
    <dbReference type="OrthoDB" id="7854943at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019774">
        <property type="term" value="C:proteasome core complex, beta-subunit complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004298">
        <property type="term" value="F:threonine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051603">
        <property type="term" value="P:proteolysis involved in protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03762">
        <property type="entry name" value="proteasome_beta_type_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.20.10:FF:000010">
        <property type="entry name" value="Proteasome subunit beta type-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.10">
        <property type="entry name" value="Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000243">
        <property type="entry name" value="Pept_T1A_subB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016050">
        <property type="entry name" value="Proteasome_bsu_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001353">
        <property type="entry name" value="Proteasome_sua/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023333">
        <property type="entry name" value="Proteasome_suB-type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32194:SF0">
        <property type="entry name" value="ATP-DEPENDENT PROTEASE SUBUNIT HSLV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32194">
        <property type="entry name" value="METALLOPROTEASE TLDD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00227">
        <property type="entry name" value="Proteasome"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00141">
        <property type="entry name" value="PROTEASOME"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="N-terminal nucleophile aminohydrolases (Ntn hydrolases)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00854">
        <property type="entry name" value="PROTEASOME_BETA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51476">
        <property type="entry name" value="PROTEASOME_BETA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 10" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8 10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="6 10 11" id="KW-0647">Proteasome</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0888">Threonine protease</keyword>
    <keyword evidence="7" id="KW-0865">Zymogen</keyword>
    <feature type="active site" description="Nucleophile" evidence="9">
        <location>
            <position position="12"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022698"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR600243-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU004203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="OBZ82561.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="211" mass="22842" checksum="64EB46A1B117922A" modified="2016-11-30" version="1">MSLKKGEVNLGTSIMAVAFKDGVILGADSRTTTGAYIANRVTDKLTKVHDTIYCCRSGSAADTQAVADIVHYYLQMYTASENEAPSVRTAAALFQELCYQNKDNLSAGVIVAGWDKKEGPCVYNIPLGGSLHKQPFAIGGSGSTYIYGYCDAYYKDDMSREECLEFVKNSLALAMSRDGSSGGVIRLAVITREGVERLFIPGNELPVHWEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N0V5</accession>
    <name>A0A1C7N0V5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Protein csx2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">csx2_0</name>
        <name evidence="9" type="ORF">A0J61_09175</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000790">
        <property type="protein sequence ID" value="OBZ82775.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N0V5"/>
    <dbReference type="FunCoup" id="A0A1C7N0V5">
        <property type="interactions" value="231"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N0V5"/>
    <dbReference type="InParanoid" id="A0A1C7N0V5"/>
    <dbReference type="OrthoDB" id="10266696at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd08204">
        <property type="entry name" value="ArfGap"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.29.30:FF:000252">
        <property type="entry name" value="ARF GTPase activator (Csx2)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.220.150:FF:000009">
        <property type="entry name" value="stromal membrane-associated protein 1 isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.220.150">
        <property type="entry name" value="Arf GTPase activating protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.60">
        <property type="entry name" value="Arfaptin homology (AH) domain/BAR domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045258">
        <property type="entry name" value="ACAP1/2/3-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027267">
        <property type="entry name" value="AH/BAR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037278">
        <property type="entry name" value="ARFGAP/RecO"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001164">
        <property type="entry name" value="ArfGAP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038508">
        <property type="entry name" value="ArfGAP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004148">
        <property type="entry name" value="BAR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001849">
        <property type="entry name" value="PH_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23180:SF160">
        <property type="entry name" value="ADP-RIBOSYLATION FACTOR GTPASE-ACTIVATING PROTEIN EFFECTOR PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23180">
        <property type="entry name" value="CENTAURIN/ARF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01412">
        <property type="entry name" value="ArfGap"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16746">
        <property type="entry name" value="BAR_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00169">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00405">
        <property type="entry name" value="REVINTRACTNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00105">
        <property type="entry name" value="ArfGap"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00233">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57863">
        <property type="entry name" value="ArfGap/RecO-like zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103657">
        <property type="entry name" value="BAR/IMD domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50115">
        <property type="entry name" value="ARFGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50003">
        <property type="entry name" value="PH_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0343">GTPase activation</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="PH" evidence="7">
        <location>
            <begin position="315"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="domain" description="Arf-GAP" evidence="8">
        <location>
            <begin position="624"/>
            <end position="756"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="287"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="471"/>
            <end position="508"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="296"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="471"/>
            <end position="486"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022468"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50115"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OBZ82775.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="938" mass="105191" checksum="3908278400621BC2" modified="2016-11-30" version="1">MSIEEENINYQQEMLDRFPPIWKNSCLDEIYLEDGPLFRATIKQLEERTVSLRTSLKRIIKTATVSLELRNQLADADKAYFYALRDTPCVEPFMTQYLSDTFTAIHEERLRLGQSLSTQLIEPLKRLYEDEIKTVDVRKRQFEEESREYYGSLSKYLKHSSNNNKTTYDQQHQVRKSKFDLARFDYLNFLLGLHGGKKENEILFCIADHTVRHVNYFGVIANKTDIEKKGLNEVFLKITNDSREQELAAQEREKKREALVARCHLSVDSEKTKFLDEEVTVEEVIAENSKKHSTKTTESQENSTQDLLQTPAAESRKKEGFLFTTSKPFKSTGAFDVTQNAATWRKYWCVLSNGQLHEYTNWKKQLELHIDPINLTLATVRKARHFERRFCFEIITPQLRRVYQATSDEEAQDWINTITNSIKGVLSGTGSAVNLLELGSQVPMPPIAPRRHRRSISGAFKSGLAAVTGTNHHGSSNLVVSPSKSTPVKLKKGTISDESTKNKMPVPPVPPIKAASVNQSQIGSNLPLAQAPLSRTASVVSSVNAPSKLASSRPPSSLFQIPFDHLESSFSAPADRNRWSGFSIGSFSFDKKDKDNGSIKSMSISSNKIQLFGLASVADSEVNSKLLSILKEDSSNHNCVDCNARDPEWCSLNLGVLLCIECSGIHRSLGTHVSKVRSLTMDTTSYTLDLIELLRSIGNARANDIWDVRISQNKANKETEIPRPGPYESHATKMAYIQAKYVGRQFVQLIDPSTDPNQILFDAIDKDDIPNALYALALGADVQSIRPNGTILTTTENQATLLPKDNQEPDQMPQYALYCALLRSRIVTEDHALYPISNSMISDIESDSQSTESSISTTPSPKRIFPMAELLLQHNADTSLVNADFVLDDQALAYLNTKMMARGQSRVIRSGSVAKPLPTEDEIAAQESIAITIADEIY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N0X2</accession>
    <name>A0A1C7N0X2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_09670</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000905">
        <property type="protein sequence ID" value="OBZ82279.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N0X2"/>
    <dbReference type="InParanoid" id="A0A1C7N0X2"/>
    <dbReference type="OrthoDB" id="2263149at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="34"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="59"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="107"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="122"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="137"/>
            <end position="175"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ82279.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="175" mass="19534" checksum="B822C7EA12151FC4" modified="2016-11-30" version="1">MNQQTYSGAHPTTTNSITEQSTLGHMEQPARTGNHPTTTDSLYEQSSLSHMEQPARTGNHPTTTDSLYEQSSLSHMEQPAQTGNHPTTLNDVTQQSATQGSHTAHHQRTERPVADKDAFIQPNETKQHLQSNISPAERAKQLASEMDKTFEERRKSADEGDKLLKIGDKKEFKLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N150</accession>
    <name>A0A1C7N150_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Cell division control protein 45</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">sna41_1</name>
        <name evidence="5" type="ORF">A0J61_09117</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the TFP11/STIP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000778">
        <property type="protein sequence ID" value="OBZ82830.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N150"/>
    <dbReference type="FunCoup" id="A0A1C7N150">
        <property type="interactions" value="728"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N150"/>
    <dbReference type="InParanoid" id="A0A1C7N150"/>
    <dbReference type="OrthoDB" id="4822at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071008">
        <property type="term" value="C:U2-type post-mRNA release spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006270">
        <property type="term" value="P:DNA replication initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000390">
        <property type="term" value="P:spliceosomal complex disassembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003874">
        <property type="entry name" value="CDC45"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000467">
        <property type="entry name" value="G_patch_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022783">
        <property type="entry name" value="GCFC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045211">
        <property type="entry name" value="TFP11/STIP/Ntr1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23329:SF1">
        <property type="entry name" value="TUFTELIN-INTERACTING PROTEIN 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23329">
        <property type="entry name" value="TUFTELIN-INTERACTING PROTEIN 11-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02724">
        <property type="entry name" value="CDC45"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01585">
        <property type="entry name" value="G-patch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07842">
        <property type="entry name" value="GCFC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00443">
        <property type="entry name" value="G_patch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50174">
        <property type="entry name" value="G_PATCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="5" id="KW-0132">Cell division</keyword>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="G-patch" evidence="4">
        <location>
            <begin position="132"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="13"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="175"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="875"/>
            <end position="899"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="321"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="3">
        <location>
            <begin position="71"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="90"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="177"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="875"/>
            <end position="893"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="1124"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50174"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OBZ82830.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="1124" mass="130010" checksum="3DAD34B4F10FA7C7" modified="2016-11-30" version="1" fragment="single">QIIYLFQMGRRKTFMEGGSSSEDEEEGGRISFNISQGDLDAEMAGFSGHQGRRPRRRFGESSDEEEDNERGGLGATLGLGLGPSFLPAQKAEEPKKKEEEKVRKNPVKEKIRARSTHSPSPGPGFAEFNKHSKGFGQKMLEKMGWSSGQGLGADGAGIVNPIETKLRPARMGLSFRGFDERTEQAKVDEKARRGNEDDEEDDEEESRKVKKRNAWKSTKAEDGHIPQQQKSRKPKTVYKTAADILAETAIEPVTQKVLDMTGPGGIREINLADIQSTDSPTWMEVTTRLPELRHNLRLLVDLTRSDLENLSREKQTNSFRMASLRKEVDTIQQSLEKEKKQLERLQQLKSIAQQLEQISKDALATGAYEQGQITSLFGEPFDLLTRDFGDQIKEFSIDALVVSVWAPIMKYKSMHWQVLDEPEWGAADVKRWRHLLIANDDHDRPLDPSDQGWTRARLQPQKEIIATPFETMMNTLWLSKIRSAINNQWDVHHPEPIIQLMEAWEPLLPRFIYENIIHQLILPKLNRAVSEWNPRTDPIMINSWIHPWFPVLKAWRLSELFSSIRQKMAVVLRQWHPSDESALHIIAPWKDVWTETQLDEFSTKYILPKLTLVLREEFRVDPRDQQMDPLIWCLAWKDILSDTILGLLLKNELFSQWHHVLVQWLSLDMYSINYDQISDWYRWWRQVFDAYGLDQNKIIMQEFRKGLDTMNRALNGEDLGLFYLMVRITNSLYREAYDYIKNDSLEGNCIIFVAPDVDSICAVRLFQSVLKTDIIQHKIVPVSGHQDLVDANTKLIEKDQDLRSIVMINCGAMESISNLFNAPEGTKIYVIDSHRPLLLENLSADNNHICVFDDESEDHRVNEVLNAYEELMQAEEDQEFSESDMDEEEDDDNDRPRQRRRLNNLEQGISLNALRSKRRQQNKLIQDYYEAGAYYANSVSGVMYELAHQLGKSSNEFGIVGVTAQYIFERIDTARYTEKLELFKDDRARLNIDRNEDGQLLNPTQVIIRAEDEYRFMLFRHWSLYESMYHSGYVSSKLGVWKDAGKKRLNNMFAKMGFSLQQCQQIYTHMDMDLKQTLRNKIEHVAPLYGLTDICFPSFTRGYGYECCMSASDVVYALSTLIET</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N154</accession>
    <name>A0A1C7N154_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_09082</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000770">
        <property type="protein sequence ID" value="OBZ82865.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N154"/>
    <dbReference type="STRING" id="101091.A0A1C7N154"/>
    <dbReference type="InParanoid" id="A0A1C7N154"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="75"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="75"/>
            <end position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ82865.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="178" mass="20251" checksum="8B3AD9F2DD141809" modified="2016-11-30" version="1">MGSGVITIRCDIVESFLAREIDITLGGQTGDTGSVRVRLKWDPQPLLRRKTQKTFMRTPRRVTTQMSTTAFNFAQPPKNISTSTSLRSDTLPQNNAMSNSTSNRSVGDMSVFSEREEAGSHDQEPVVEDHLEEFVEHGEKQNPLAKIYRKGHKLFHMKRSKKQIFPQLRRIVMKCDTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N160</accession>
    <name>A0A1C7N160_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_09586</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000885">
        <property type="protein sequence ID" value="OBZ82359.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N160"/>
    <dbReference type="InParanoid" id="A0A1C7N160"/>
    <dbReference type="OrthoDB" id="2261617at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="21"/>
            <end position="118"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ82359.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="275" mass="32497" checksum="DFC4F0B4032524BD" modified="2016-11-30" version="1">MSPPRTAKVRPQPNSPIKKNLDQWIHEYELLQNEIVKTQLEIDSVKRTNARHEKEAMQYTQSNKTYRARIKEIMQQIESKQMALETTKGTSSQLELKVKQLKDEALRSRGQLEHLRKREHVLVQERELIAKEKKQVELQLHIMKESVHQLRMRCDRETALLRRDHLCIREQINYIYQRTAYTQELIELKLLRRRQALEYLHTLQSQSKSNLKAFVDHVRDQLKALNEGLEQSTFMPSQATTTMSAVSQCQDDVERLVKRIRSMAVEAIEQSHSFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N189</accession>
    <name>A0A1C7N189_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">5'-3' exoribonuclease</fullName>
            <ecNumber evidence="15">3.1.13.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="19" type="primary">rat1</name>
        <name evidence="19" type="ORF">A0J61_09088</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="19 20" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19 20">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="15">Possesses 5'-&gt;3' exoribonuclease activity. May promote termination of transcription by RNA polymerase II.</text>
    </comment>
    <comment type="function">
        <text evidence="13">Possesses 5'-&gt;3' exoribonuclease activity. Required for the processing of nuclear mRNA and rRNA precursors. May promote the termination of transcription by RNA polymerase II. Essential for vegetative cell growth and chromosome segregation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="14">Interacts with RAI1; the interaction is direct, stabilizes RAT1 protein structure and may stimulate its exoribonuclease activity. The interaction also stimulates RAI1 pyrophosphohydrolase activity, probably by recruiting it to mRNA substrates.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 15">Belongs to the 5'-3' exonuclease family. XRN2/RAT1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="19">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.13.-" evidence="15"/>
    <dbReference type="EMBL" id="LUGH01000771">
        <property type="protein sequence ID" value="OBZ82862.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N189"/>
    <dbReference type="FunCoup" id="A0A1C7N189">
        <property type="interactions" value="1048"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N189"/>
    <dbReference type="InParanoid" id="A0A1C7N189"/>
    <dbReference type="OrthoDB" id="372487at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090730">
        <property type="term" value="C:Las1 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0110103">
        <property type="term" value="C:RNA polymerase II termination complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004534">
        <property type="term" value="F:5'-3' RNA exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000448">
        <property type="term" value="P:cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0110155">
        <property type="term" value="P:NAD-cap decapping"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034244">
        <property type="term" value="P:negative regulation of transcription elongation by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071028">
        <property type="term" value="P:nuclear mRNA surveillance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071035">
        <property type="term" value="P:nuclear polyadenylation-dependent rRNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051984">
        <property type="term" value="P:positive regulation of chromosome segregation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:1904595">
        <property type="term" value="P:positive regulation of termination of RNA polymerase II transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0180037">
        <property type="term" value="P:rapid tRNA decay"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043144">
        <property type="term" value="P:sno(s)RNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030847">
        <property type="term" value="P:termination of RNA polymerase II transcription, exosome-dependent"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030846">
        <property type="term" value="P:termination of RNA polymerase II transcription, poly(A)-coupled"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd18673">
        <property type="entry name" value="PIN_XRN1-2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.1050:FF:000002">
        <property type="entry name" value="5'-3' exoribonuclease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.12390:FF:000003">
        <property type="entry name" value="5'-3' exoribonuclease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.12390:FF:000005">
        <property type="entry name" value="5'-3' exoribonuclease 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.1050">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12390">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027073">
        <property type="entry name" value="5_3_exoribonuclease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041412">
        <property type="entry name" value="Xrn1_helical"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004859">
        <property type="entry name" value="Xrn1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017151">
        <property type="entry name" value="Xrn2/3/4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001878">
        <property type="entry name" value="Znf_CCHC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12341:SF41">
        <property type="entry name" value="5'-3' EXORIBONUCLEASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12341">
        <property type="entry name" value="5'-&gt;3' EXORIBONUCLEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17846">
        <property type="entry name" value="XRN_M"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03159">
        <property type="entry name" value="XRN_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037239">
        <property type="entry name" value="Exonuclease_Xrn2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50158">
        <property type="entry name" value="ZF_CCHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="8 15" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="7 15" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="16" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 15" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="6 15" id="KW-0540">Nuclease</keyword>
    <keyword evidence="12" id="KW-0539">Nucleus</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="11" id="KW-0804">Transcription</keyword>
    <keyword evidence="9" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="3" id="KW-0806">Transcription termination</keyword>
    <keyword evidence="16" id="KW-0862">Zinc</keyword>
    <keyword evidence="16" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="CCHC-type" evidence="18">
        <location>
            <begin position="266"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="409"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="485"/>
            <end position="539"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="911"/>
            <end position="978"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="17">
        <location>
            <begin position="425"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="17">
        <location>
            <begin position="487"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="17">
        <location>
            <begin position="500"/>
            <end position="532"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="17">
        <location>
            <begin position="914"/>
            <end position="927"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="17">
        <location>
            <begin position="937"/>
            <end position="948"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="17">
        <location>
            <begin position="964"/>
            <end position="978"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006994"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022472"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00046137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00046943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PIRNR" id="PIRNR037239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS50158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="OBZ82862.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="1019" mass="116585" checksum="390B568C916D3C56" modified="2016-11-30" version="1">MGVPAFFRWLSDKFPKVVSTVIEEHPKEINGTRLPVDTTKPNPNGQEFDNLYLDMNGIIHPCCHPENKPAPSSEDEMMIAIFEYTDRIVDMIRPRKLLYMAIDGVAPRAKMNQQRSRRFRAAQLAQVEKDAADRVFQELDAIGQAHQLPEKKKHFDSNCITPGTPFMAHLAACLRYHIAAKQNSDPLWKNLKVILSDATVPGEGEHKVMEFIRVQRMRPEHNPNTTHVMYGLDADLIMLALATHEPHFKVLREDVFEDKRKKKGVCFKCNQPGHAITQCQASDEAIEAMRQQEQNTDTPPKPYVFLHVNVLREYLEHALKFNIPGLVWDLERAIDDWVFMCFFVGNDFLPHLPSLEIREGAISTLSLLWKQTMPQMGGYMTQNGDVDLKRVQVLVTELGKMEDNIFSERKQSEERRAQGAKRRRLENERRARETKMFDPNGNFGDMTAAPVNQPHAGMSNSDVIANRAQIRMANINAAAALRAELSGGHEESKKRKLDDTEIEQEQKEEEEQQPEEDVQEEEEEEEMDESDSAPESAEAVGQAILKRVADEKKEKEEAARKREPDDEVRLWEAGWKERYYKTKFNLTLTDRDEIRHIVKSYCEGLIWVFKYYYLGCVSWSWYYPYHYAPMASDFVHIDSFDIQFEQSAPLKPFEQLMGVLPAASKDHIPKPFHHLMTDADSPIIDYYPTQFEVDMDGKKWEWQGVVKLPFIDSARLLEAMSAVYDQLNEEETQRNSTGQSVLYVSESHKAYNAISTVYTKRNEDALKLDARLTDGLTGRVDRDQDCIPRSTLYTPLPDFDLPDIANDKSISVVYALPEFPEGFKFSTQLLKGVKLNTALGYEDVQLATFEKVDPRQRYSGNRGWTAQVNHLEDYRQYNNPRHRTGGRNNGYYQQQQQQGYGAGYNHGFDDGSYFPNNNYGYRPQHQQQRGHHSNNGGYQGGYQQGGYNNGYSNGYNNNGGGYRRGYNQNNNQGYHNGNNYNNNGGGYGNGNGGGYGNNNGGGYGNGGGYGNQNYHHRRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N1F1</accession>
    <name>A0A1C7N1F1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Protein sel-1 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">SEL1L2_1</name>
        <name evidence="3" type="ORF">A0J61_09027</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the sel-1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000757">
        <property type="protein sequence ID" value="OBZ82923.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N1F1"/>
    <dbReference type="InParanoid" id="A0A1C7N1F1"/>
    <dbReference type="OrthoDB" id="442451at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006597">
        <property type="entry name" value="Sel1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050767">
        <property type="entry name" value="Sel1_AlgK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11102:SF160">
        <property type="entry name" value="ERAD-ASSOCIATED E3 UBIQUITIN-PROTEIN LIGASE COMPONENT HRD3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11102">
        <property type="entry name" value="SEL-1-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08238">
        <property type="entry name" value="Sel1"/>
        <property type="match status" value="27"/>
    </dbReference>
    <dbReference type="SMART" id="SM00671">
        <property type="entry name" value="SEL1"/>
        <property type="match status" value="26"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81901">
        <property type="entry name" value="HCP-like"/>
        <property type="match status" value="8"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="11"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="21"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="41"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="59"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="79"/>
            <end position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00038101"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ82923.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="1798" mass="201853" checksum="E249D97E8D22DD64" modified="2016-11-30" version="1">MGAKPSKQSDEYSQSLQTNHLLRKKKHNFRAALSRKKKVNVPSSPLSPTSVIPTAPIITINSHATPPSCTTNKYEESTHSNNGKKPLSNQSSISTTSRHSNHTSPYDSSRSKKSKRSRLLSATSNNNTALKHLSIISNNTIASSDYVGFYSDKSNISSTAWTVLSNDPFSQIEASASAFTEITDHSTISRKSLYNVAGPSTSPPSYYHTKFNNTSSIIQNNAGPAPVLTQDILSQLKQYPSQSYRIIQESYQHAQQQNDPFDWTQFYHAIHQYSKIADASNKSIAIVYLAKCLIFGFGVNQDIERGFNLLHSHPSCETSYALGRCYLDGVPSPDNKRIDKIAAFECFKVASEYTPTNDSILNTVAEAQCILARMLFQGEGVTQNTEEALKYLMMSASNDNMYAQFLVGVHYERGIDVTQDLEKARHYYGKSAEGGFPDAQAALGSRLVAEQNYTEGIEWLEKAIQMGNSRAHVQLGILYDKGEGVEQNNDMALLHYKAAVESNNYAAQYILGLVYYFGRLGRQKNHKEAIRLIKQSAMAGLPYAQRVLGQLYQQGSIVSSQDAGSNVDSRLRTKRNEREAIRWYKRAATGKDVAAMAILGKCHEQGVGVEMDLEKALAFYTKAAEIDSPYVYNILIDQAILLQKMARHTEAFDLYSKVLTAEQSEKHRQPIQTARLSVARYHLCRDIEGVPYDPLLAHTMLLDLTEETSDSQAHYWLGSIYDEGIPGLFEIDRQKAFHHFTIAAEGGDNDATFLVAYMMSNHIIPDKGPADAFPWYQKAAINGHPMSMHSLGLCFYKGIGQLDNKPELDVALEWFEKAARYGVIQSVPYMARIYLQLMISHVNDPQQNQQFLSKAIQCLKRATENNDTYAQRELGKIYLTGHGLPVDHVAAAELLGKAASKNDAEAITFLGDCYHKGTGIERDLEKAIECYLHAAELGYPYAYSAAAELYYEVGDMEHAYDYYLLASKQTKIAQNNIGKTARMMVARLSLGYIPPAQANPLLLRALLASKKTVSEQSAFEMLLTLATQDRFPQAYQPLGCCFLHGKGTSVDPKQAVSWFKKSAEELNDSIAYFNLADIFGSGLVSGISVDITLALAYLRKSADLGYTEAQFRMGIVYLQGEYGVRVDERAAANFFKLSASKSHAESVWMLSQMSSMIGQHELELQYQKQAASLGHVLSMRVLGQRFLKQLDASFLNNAMQHEYLDEALKYLHMAGESGDIQSLILLGKTYNNCLKTKVKFSASHHFPTPDDNXDEGESRFQSEEDEKNLAIECFEKASNLGSIDATVYAAEAWYEQKQFAAALEYFKKAANQGSVLARFFCARYYIEGYGGSPLDPEKGFQELLICANELNCIHAYNAIGQCYENGIGTTKDDQLAFEWYIRAAETTHDAEAYYRIAVMYAQERISTHNHHHLEACKYFDLAINITPDNHGQSCYQLGLYYLHGIQEGDAYVLSPDTCLAIEYLRTAADLGIQEAMYQLGTLFLNDDYSVEEQEEAVSLLQRAADLGLREAQFELGLLYHRGKEISLSKNDQHHNDSRGQAREEEGYNLLPQDFERAYDLFCRSAAQKHPTATYYLGVYHQHGIFVAPDLTIALEQYESAVDLFDLYETIPNRWQAEFNLASILHQDPQSRARAYELFQAANFHAPLESRFLPQIMIARYHLYGWANVAIQSKDAMAALIQFAQDEKIGCRVYLDLAQCFEHGIGVEKDLVQAFHWYGEIISKSYIIEQQQDPMLFDEEFEEQEAIAMFKLAEFYRKGMIVQKDTLKADNLYRLAAQKGSSAAQEYLSIMLQETTLSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N290</accession>
    <name>A0A1C7N290_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">H(+)-transporting two-sector ATPase</fullName>
            <ecNumber evidence="4">7.1.2.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="primary">ATP2_1</name>
        <name evidence="17" type="ORF">A0J61_08738</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>ATP + H2O + 4 H(+)(in) = ADP + phosphate + 5 H(+)(out)</text>
            <dbReference type="Rhea" id="RHEA:57720"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="7.1.2.2"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="3">F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ATPase alpha/beta chains family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="7.1.2.2" evidence="4"/>
    <dbReference type="EMBL" id="LUGH01000701">
        <property type="protein sequence ID" value="OBZ83212.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N290"/>
    <dbReference type="STRING" id="101091.A0A1C7N290"/>
    <dbReference type="InParanoid" id="A0A1C7N290"/>
    <dbReference type="OrthoDB" id="14523at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045259">
        <property type="term" value="C:proton-transporting ATP synthase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046933">
        <property type="term" value="F:proton-transporting ATP synthase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042776">
        <property type="term" value="P:proton motive force-driven mitochondrial ATP synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd18115">
        <property type="entry name" value="ATP-synt_F1_beta_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.10.170:FF:000004">
        <property type="entry name" value="ATP synthase subunit beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.170">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050053">
        <property type="entry name" value="ATPase_alpha/beta_chains"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004100">
        <property type="entry name" value="ATPase_F1/V1/A1_a/bsu_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036121">
        <property type="entry name" value="ATPase_F1/V1/A1_a/bsu_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000194">
        <property type="entry name" value="ATPase_F1/V1/A1_a/bsu_nucl-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15184">
        <property type="entry name" value="ATP SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15184:SF71">
        <property type="entry name" value="ATP SYNTHASE SUBUNIT BETA, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00006">
        <property type="entry name" value="ATP-synt_ab"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02874">
        <property type="entry name" value="ATP-synt_ab_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50615">
        <property type="entry name" value="N-terminal domain of alpha and beta subunits of F1 ATP synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="13" id="KW-0066">ATP synthesis</keyword>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="12" id="KW-0139">CF(1)</keyword>
    <keyword evidence="7" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="10" id="KW-0406">Ion transport</keyword>
    <keyword evidence="11" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-1278">Translocase</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ATPase F1/V1/A1 complex alpha/beta subunit N-terminal" evidence="16">
        <location>
            <begin position="39"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="domain" description="ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding" evidence="15">
        <location>
            <begin position="164"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="17">
        <location>
            <position position="202"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011648"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023196"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023310"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00048383"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF00006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF02874"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="OBZ83212.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="202" mass="21138" checksum="E6F76EB3E1C976E9" modified="2016-11-30" version="1" fragment="single">MFISRALGRVASGAFRNPMAAQAASSARKYATAASAGQIRSVIGAVVDVQFEQDNLPAILNALEVKDHAGGRLVLEVAQHLGENTVRTIAMDGTEGLVRGQKVVDTGAPITIPVGKEVLGRIINVIGEPIDERGPINTKAHRPIHAEAPEFVDQSPTPEILETGIKVVDLLAPYARGGKIGLFGGAGVGKTVLIQELINNIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N2F4</accession>
    <name>A0A1C7N2F4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">GDP-mannose transporter</fullName>
            <shortName evidence="5">GMT</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">VRG4</name>
        <name evidence="7" type="ORF">A0J61_08704</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Involved in the import of GDP-mannose from the cytoplasm into the Golgi lumen.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Homooligomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Golgi apparatus membrane</location>
            <topology evidence="5">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="5">Cytoplasmic vesicle membrane</location>
            <topology evidence="5">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="5">Endoplasmic reticulum membrane</location>
            <topology evidence="5">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the TPT transporter family. SLC35D subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000696">
        <property type="protein sequence ID" value="OBZ83247.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N2F4"/>
    <dbReference type="FunCoup" id="A0A1C7N2F4">
        <property type="interactions" value="228"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N2F4"/>
    <dbReference type="InParanoid" id="A0A1C7N2F4"/>
    <dbReference type="OrthoDB" id="417037at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030659">
        <property type="term" value="C:cytoplasmic vesicle membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037185">
        <property type="entry name" value="EmrE-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050186">
        <property type="entry name" value="TPT_transporter"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00803">
        <property type="entry name" value="nst"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11132">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103481">
        <property type="entry name" value="Multidrug resistance efflux transporter EmrE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0968">Cytoplasmic vesicle</keyword>
    <keyword evidence="5" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="5" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0762">Sugar transport</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="40"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="67"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="132"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="159"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="196"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="227"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="266"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="295"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="321"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="355"/>
            <end position="374"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU367097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OBZ83247.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="374" mass="41297" checksum="A5D53923882B3821" modified="2016-11-30" version="1">MGETKPDYSVVIDQEPDQQKRQQNTVVAPSGIKLSPGMRAILPIASYCGASILMTVTNKYVLSGYDFNMNFLLLTIQNLTCVVLLQSFKFLNLIKFRDFDSDEARKWSPIALSLVAMIYTGSKALQFLRIPIYTIFKNLTIILIAYGEVLWFGGNVTRFMLVSFGLMVFSSVIAGWADISETVTQIVEFDTTVLGYFWMASNCLASAAFVLYMRKRIKLTNFKDFDTVYYNNLVSIPMLIIPSFIFEDWSAEGLSKNFPVEVRQSMLIAMIFSGVSAFAMSYASAWCVRTTSSTTYSMVGALNKLPIAASGILFFDDPATFGNVSAIVVGFVAGIVYSIAKTTANKTANTNKDIIPMSSSSQSNADAVKDHGKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N2S3</accession>
    <name>A0A1C7N2S3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Large ribosomal subunit protein mL50</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">39S ribosomal protein L50, mitochondrial</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">A0J61_08497</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the mitochondrion-specific ribosomal protein mL50 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000660">
        <property type="protein sequence ID" value="OBZ83455.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N2S3"/>
    <dbReference type="InParanoid" id="A0A1C7N2S3"/>
    <dbReference type="OrthoDB" id="6220758at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005762">
        <property type="term" value="C:mitochondrial large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.10">
        <property type="entry name" value="ACP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036736">
        <property type="entry name" value="ACP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018305">
        <property type="entry name" value="Ribosomal_m50"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31542">
        <property type="entry name" value="39A RIBOSOMAL PROTEIN L50, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31542:SF1">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN ML50"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10501">
        <property type="entry name" value="Ribosomal_L50"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008860"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00035183"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00035398"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OBZ83455.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="175" mass="20130" checksum="8E90D01BD1FBFC21" modified="2016-11-30" version="1">MIPSRRIFALASTRYIHTTRAMMAESDGLFGKINPWAKKEQTPVQPTTTEEETKVTFNVDYEDAEEIISWKRSDVLTDVDAIETTVKSVIQHHLPQATETSLPLDDLNIKFQILKDSMQQTGKEVPNYQLNQLKTTQDILEFFKGSFDQKELTVETFFEEHKDTLPSNLTFAARE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N3I6</accession>
    <name>A0A1C7N3I6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Small ribosomal subunit protein uS9m</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">37S ribosomal protein S9, mitochondrial</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">mrp-9</name>
        <name evidence="7" type="ORF">A0J61_08309</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the universal ribosomal protein uS9 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000628">
        <property type="protein sequence ID" value="OBZ83640.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N3I6"/>
    <dbReference type="FunCoup" id="A0A1C7N3I6">
        <property type="interactions" value="246"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N3I6"/>
    <dbReference type="InParanoid" id="A0A1C7N3I6"/>
    <dbReference type="OrthoDB" id="10254627at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005763">
        <property type="term" value="C:mitochondrial small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.230.10:FF:000001">
        <property type="entry name" value="30S ribosomal protein S9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_Su5_D2-typ_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000754">
        <property type="entry name" value="Ribosomal_uS9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023035">
        <property type="entry name" value="Ribosomal_uS9_bac/plastid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020574">
        <property type="entry name" value="Ribosomal_uS9_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribsml_uS5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF001099">
        <property type="entry name" value="PRK00132.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21569">
        <property type="entry name" value="RIBOSOMAL PROTEIN S9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21569:SF1">
        <property type="entry name" value="SMALL RIBOSOMAL SUBUNIT PROTEIN US9M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00380">
        <property type="entry name" value="Ribosomal_S9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="Ribosomal protein S5 domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00360">
        <property type="entry name" value="RIBOSOMAL_S9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 6 7" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00039318"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00042623"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003815"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OBZ83640.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="298" mass="33852" checksum="186F1A63C54A319D" modified="2016-11-30" version="1">MSSLLRIARIVPTAVRANVARQPLPAFTSMTQRFASNYQQVHQQQNDDVLQYREKPGSLSYFTGNYKYNDLLIEFDALYKRFEDWKPSEQTAAAPQTDKAHSWKQRDKMSQLLSIPLTTSQWRKITAHLNMLASLPKPLPPAVAKIIEPYGRFDATQQGASEQKTHSLDDMGRAYAVGRRKESSARCYLVEGEGKVLINGLELNEYFQRPVDRDEVTLPFEVTDSKEKYSAWIVVKGGGSTGQAQAIKLGLGKALLIHNNELKPVLRKAGCITRDPRVVERKKEGQRKARAKYTWVKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N3K8</accession>
    <name>A0A1C7N3K8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Maleylacetoacetate isomerase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">mai</name>
        <name evidence="4" type="ORF">A0J61_08723</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the GST superfamily. Zeta family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000699">
        <property type="protein sequence ID" value="OBZ83226.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N3K8"/>
    <dbReference type="STRING" id="101091.A0A1C7N3K8"/>
    <dbReference type="InParanoid" id="A0A1C7N3K8"/>
    <dbReference type="OrthoDB" id="202840at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004364">
        <property type="term" value="F:glutathione transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016034">
        <property type="term" value="F:maleylacetoacetate isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006749">
        <property type="term" value="P:glutathione metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006559">
        <property type="term" value="P:L-phenylalanine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd03191">
        <property type="entry name" value="GST_C_Zeta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03042">
        <property type="entry name" value="GST_N_Zeta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1050.10:FF:000010">
        <property type="entry name" value="Maleylacetoacetate isomerase isoform 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1050.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010987">
        <property type="entry name" value="Glutathione-S-Trfase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036282">
        <property type="entry name" value="Glutathione-S-Trfase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040079">
        <property type="entry name" value="Glutathione_S-Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004045">
        <property type="entry name" value="Glutathione_S-Trfase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004046">
        <property type="entry name" value="GST_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005955">
        <property type="entry name" value="GST_Zeta"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034330">
        <property type="entry name" value="GST_Zeta_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034333">
        <property type="entry name" value="GST_Zeta_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01262">
        <property type="entry name" value="maiA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42673">
        <property type="entry name" value="MALEYLACETOACETATE ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42673:SF4">
        <property type="entry name" value="MALEYLACETOACETATE ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14497">
        <property type="entry name" value="GST_C_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13409">
        <property type="entry name" value="GST_N_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00019">
        <property type="entry name" value="Glutathione_Transferase_(cytos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG00358">
        <property type="entry name" value="Main_(cytGST)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47616">
        <property type="entry name" value="GST C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50405">
        <property type="entry name" value="GST_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50404">
        <property type="entry name" value="GST_NTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0413">Isomerase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GST N-terminal" evidence="2">
        <location>
            <begin position="5"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="domain" description="GST C-terminal" evidence="3">
        <location>
            <begin position="92"/>
            <end position="215"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OBZ83226.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="220" mass="25054" checksum="7D2410CDF65BBDC1" modified="2016-11-30" version="1">MSTEQTPVLYGYFRSSASWRLRIALEWKGIQYELRPVNLLTGENKSEEYRQVNPTGKVPAFVTKDGKILSQSQAIIEYLEETYPERPMLPKCTTKRAEVREICQIIACDIHPIQNLGVIKRIEEISSMSKEEWAKSSITLGFEGLEKRLEHVSGTYSVGDSITMADFYLCSIVGNAHRWGVDMSLFPIITRINNTLMTLPEFIAASPFSQPDCPEELRKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N445</accession>
    <name>A0A1C7N445_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">54S ribosomal protein L20, mitochondrial</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_08513</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000663">
        <property type="protein sequence ID" value="OBZ83436.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N445"/>
    <dbReference type="FunCoup" id="A0A1C7N445">
        <property type="interactions" value="63"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N445"/>
    <dbReference type="InParanoid" id="A0A1C7N445"/>
    <dbReference type="OrthoDB" id="6021263at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005762">
        <property type="term" value="C:mitochondrial large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024388">
        <property type="entry name" value="Ribosomal_mL58"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28266">
        <property type="entry name" value="54S RIBOSOMAL PROTEIN L20, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28266:SF1">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN ML58"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12824">
        <property type="entry name" value="MRP-L20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ83436.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="141" mass="16141" checksum="7AED92EE3D85BB68" modified="2016-11-30" version="1">MNNSRQLFSSIRTYATKSKTTNLKYKPSVPVEYTTLSDGTIFIERQPVVPPSIQSQVAPLLRKTAPKSKLTDSQIAELRQLRESDPTTWTRSKLAKKFNCSELFVGMVAPLKEAPVVQEQANHGYRHKLILEQRQKRKALW</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-06-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N535</accession>
    <name>A0A1C7N535_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_07799</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000548">
        <property type="protein sequence ID" value="OBZ84151.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N535"/>
    <dbReference type="InParanoid" id="A0A1C7N535"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ84151.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="86" mass="10209" checksum="825E95AA706D1D7E" modified="2016-11-30" version="1">MSKSQYQKEKEYMTKQNLFLMLSDDFREDVYNRQGQPSADLQIRESANSIMHENSFEKLAFHALYNVYEAKHSGFFLDEFGSYCEC</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N580</accession>
    <name>A0A1C7N580_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Thiamine pyrophosphokinase</fullName>
            <ecNumber evidence="7">2.7.6.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">TPK1_0</name>
        <name evidence="9" type="ORF">A0J61_07656</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>thiamine + ATP = thiamine diphosphate + AMP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:11576"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:18385"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:58937"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 7">Cofactor biosynthesis; thiamine diphosphate biosynthesis; thiamine diphosphate from thiamine: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the thiamine pyrophosphokinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.6.2" evidence="7"/>
    <dbReference type="EMBL" id="LUGH01000529">
        <property type="protein sequence ID" value="OBZ84295.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N580"/>
    <dbReference type="STRING" id="101091.A0A1C7N580"/>
    <dbReference type="InParanoid" id="A0A1C7N580"/>
    <dbReference type="OrthoDB" id="25149at2759"/>
    <dbReference type="UniPathway" id="UPA00060">
        <property type="reaction ID" value="UER00597"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030975">
        <property type="term" value="F:thiamine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004788">
        <property type="term" value="F:thiamine diphosphokinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009229">
        <property type="term" value="P:thiamine diphosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006772">
        <property type="term" value="P:thiamine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07995">
        <property type="entry name" value="TPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.10240:FF:000006">
        <property type="entry name" value="Thiamin pyrophosphokinase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.120.320:FF:000001">
        <property type="entry name" value="Thiamine pyrophosphokinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10240">
        <property type="entry name" value="Thiamin pyrophosphokinase, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.320">
        <property type="entry name" value="Thiamin pyrophosphokinase, thiamin-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006282">
        <property type="entry name" value="Thi_PPkinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016966">
        <property type="entry name" value="Thiamin_pyrophosphokinase_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007373">
        <property type="entry name" value="Thiamin_PyroPKinase_B1-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036371">
        <property type="entry name" value="TPK_B1-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007371">
        <property type="entry name" value="TPK_catalytic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036759">
        <property type="entry name" value="TPK_catalytic_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01378">
        <property type="entry name" value="thi_PPkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13622">
        <property type="entry name" value="THIAMIN PYROPHOSPHOKINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13622:SF8">
        <property type="entry name" value="THIAMIN PYROPHOSPHOKINASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04265">
        <property type="entry name" value="TPK_B1_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04263">
        <property type="entry name" value="TPK_catalytic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF031057">
        <property type="entry name" value="Thiamin_pyrophosphokinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00983">
        <property type="entry name" value="TPK_B1_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63999">
        <property type="entry name" value="Thiamin pyrophosphokinase, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63862">
        <property type="entry name" value="Thiamin pyrophosphokinase, substrate-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 7 9" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Thiamin pyrophosphokinase thiamin-binding" evidence="8">
        <location>
            <begin position="178"/>
            <end position="243"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006785"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRNR" id="PIRNR031057"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00983"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OBZ84295.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="253" mass="28363" checksum="CECE5A123FF8E9B0" modified="2016-11-30" version="1">MQANSSITHWTPSNILSTDGKTKSFCLIVLNQPIHHIDTFSHLWNNASFRFVADGGSNRLYDAFQHNPDLLAKYLPDEIRGDLDSIRPDVQAYYESKHVKITKVHDQDSTDFMKCVALLHEKEKEQGMIYDIVATPALGGRFDQTISNIHLLYTVKDHAGRRAILVSDENLTMLLDKGKHHVHCQLDMEGPTCGIMPMGAPAILTTKGLRWNLTNTKCALGGILSTSNIVDNELIEIETDAPVVWTIEINRSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N5T9</accession>
    <name>A0A1C7N5T9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_09237</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000805">
        <property type="protein sequence ID" value="OBZ82714.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N5T9"/>
    <dbReference type="InParanoid" id="A0A1C7N5T9"/>
    <dbReference type="OrthoDB" id="10377902at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ82714.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="68" mass="7948" checksum="D5A51EA262E2A49B" modified="2016-11-30" version="1">MNGLFFFCKIAQIKIPTTEADFKSLGVYFNDIAMIRQAYKSNCHQKETDEQQFETLPWSVFSEMACKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N6U8</accession>
    <name>A0A1C7N6U8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein C4H3.03c</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">A0J61_08906</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000733">
        <property type="protein sequence ID" value="OBZ83044.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N6U8"/>
    <dbReference type="FunCoup" id="A0A1C7N6U8">
        <property type="interactions" value="2"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N6U8"/>
    <dbReference type="InParanoid" id="A0A1C7N6U8"/>
    <dbReference type="OrthoDB" id="406733at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008928">
        <property type="entry name" value="6-hairpin_glycosidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012341">
        <property type="entry name" value="6hp_glycosidase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011613">
        <property type="entry name" value="GH15-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045582">
        <property type="entry name" value="Trehalase-like_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31616:SF0">
        <property type="entry name" value="GLUCAN 1,4-ALPHA-GLUCOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31616">
        <property type="entry name" value="TREHALASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00723">
        <property type="entry name" value="Glyco_hydro_15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19291">
        <property type="entry name" value="TREH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48208">
        <property type="entry name" value="Six-hairpin glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Trehalase-like N-terminal" evidence="3">
        <location>
            <begin position="84"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="domain" description="GH15-like" evidence="2">
        <location>
            <begin position="375"/>
            <end position="750"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="49"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="51"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF19291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OBZ83044.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="860" mass="99257" checksum="7D83E8D3D3B775B6" modified="2016-11-30" version="1">MSFSENNDDKDRSYGLQLEYEIEESEKPCEQLPDGVRYIADTRRQSVMNNRADECSNERNDKEKPGTNTNVEDTRCNVRKRGYLPIENYGIIGNMRTIALVGTDASVDFFCFPKFDSPSIFCRMLDKDKGGHFSISPRRPHTSNKQMYLPNSNILATRFLSDDGVAEIIDYMHVPAQGQRESTKPLLQWLIRKVRVIRGTVEFKMECYPAFNYAMDDHTTEIVKDDSSEDQKNAAGFEAKLYPEEETNYYAGNDRVVFKSKDLTMDLRHLVRCGDFDCPVIKINIDKECDDHKGPGVWTEFDLKETQEITFIFREAPKHKQDKEKEKKDESAAERRLRLAEDPPLTVSLLDALFRQTSTYWLNWVSQSTYKGSWRENVMRSALTLKLLTYEPTGAVVAAPTFGIPEAIGGPRNWDYRYVWIRDSSFTIYAFLRLGFTHEAGEYMKYISERCSDLNEDGSLNIMYSIDGVKELAEYELDHLDGYRGSRPVRVGNGAYDHLQLDIYGELMDGIYLYNKYGSPISYDMWCSVRQLANYVCDNWNVPDMSIWEVRGRKQQFTYSLVMCWVALDRALRLAEKRVFPCPDRNKWMDARDEIYELVQNKCYNKKLKMFAQSVESPDALDASTLIMPLVFFISPTDPRLLNTIRRTLLPPEKGGLVANDLVFRYNFLTTDDGVGGLEGAFSMCTFWLVEALTRAGRYDRKLLDRAVVMFEKMLSYGNHLGLFSEEVARSGELLGNFPQAFTHLSFISVQICSQLNATENIRGIHFSFSKDGAIHSLRFWTRIKSVYAIDIEVDDRFVALKSHRFNRRSPSEDDMLASPKLVYVNYHNVDEKNHDKHMFLESPPAWSPPYSEKTINHLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N6X1</accession>
    <name>A0A1C7N6X1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Cyclin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">psl1_0</name>
        <name evidence="3" type="ORF">A0J61_07080</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the cyclin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000460">
        <property type="protein sequence ID" value="OBZ84870.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N6X1"/>
    <dbReference type="FunCoup" id="A0A1C7N6X1">
        <property type="interactions" value="49"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N6X1"/>
    <dbReference type="InParanoid" id="A0A1C7N6X1"/>
    <dbReference type="OrthoDB" id="1060854at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000307">
        <property type="term" value="C:cyclin-dependent protein kinase holoenzyme complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016538">
        <property type="term" value="F:cyclin-dependent protein serine/threonine kinase regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019901">
        <property type="term" value="F:protein kinase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd20558">
        <property type="entry name" value="CYCLIN_ScPCL7-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.10">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036915">
        <property type="entry name" value="Cyclin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012389">
        <property type="entry name" value="Cyclin_P/U"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013922">
        <property type="entry name" value="Cyclin_PHO80-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15615">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15615:SF94">
        <property type="entry name" value="PHO85 CYCLIN-6-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08613">
        <property type="entry name" value="Cyclin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF027110">
        <property type="entry name" value="PREG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47954">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 2" id="KW-0195">Cyclin</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRNR" id="PIRNR027110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ84870.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="216" mass="25519" checksum="F64B8F7915853DA1" modified="2016-11-30" version="1">MAKKQQRLPYFDLANFPVLETIKMLTCLLEKITKANDSLHGPPSSFYTCFHARSIPTIDIQAYLIRILKYCPCANECFLSLLVYFDRMSQNKEHALRIDSYSIHRLIIAGIMISSKFFSDVFFTNTRYAKVGGLPVKELNLLELEFLRMNNYNINVPFEELQRYGDQLLMHSIKEREAVYRREKVHLDQQFLCSKQQQHKQRQSACYQTHNPRFYS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N767</accession>
    <name>A0A1C7N767_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="13">CTD kinase subunit alpha</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">lsk1</name>
        <name evidence="13" type="ORF">A0J61_06974</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.22"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.22"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:10216"/>
            <dbReference type="Rhea" id="RHEA-COMP:11321"/>
            <dbReference type="Rhea" id="RHEA-COMP:11322"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43176"/>
            <dbReference type="ChEBI" id="CHEBI:68546"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.23"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000447">
        <property type="protein sequence ID" value="OBZ84980.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N767"/>
    <dbReference type="FunCoup" id="A0A1C7N767">
        <property type="interactions" value="199"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N767"/>
    <dbReference type="InParanoid" id="A0A1C7N767"/>
    <dbReference type="OrthoDB" id="204883at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008024">
        <property type="term" value="C:cyclin/CDK positive transcription elongation factor complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030332">
        <property type="term" value="F:cyclin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004693">
        <property type="term" value="F:cyclin-dependent protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008353">
        <property type="term" value="F:RNA polymerase II CTD heptapeptide repeat kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032968">
        <property type="term" value="P:positive regulation of transcription elongation by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07840">
        <property type="entry name" value="STKc_CDK9_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000415">
        <property type="entry name" value="CMGC/CDK/CRK7 protein kinase, variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000124">
        <property type="entry name" value="Cyclin-dependent kinase 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050108">
        <property type="entry name" value="CDK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24056">
        <property type="entry name" value="CELL DIVISION PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24056:SF546">
        <property type="entry name" value="CYCLIN-DEPENDENT KINASE 12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 13" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="12">
        <location>
            <begin position="295"/>
            <end position="579"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="227"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="604"/>
            <end position="625"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="53"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="240"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="324"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047811"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00048367"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00049280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="OBZ84980.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="625" mass="72122" checksum="C08079EB781AAC0B" modified="2016-11-30" version="1">MDDRTHSKSRDKSTDRSQDRKSTSEKRSREEHYGRSRSRDRYRSSSSHREKRRNYDRYDRRHRDKSRDRWSSTRRSSKERDSRNRKDSNRTAYHRCDSTKQDELPLGPKAETVLRSKQEQPPTAPAAYYQPPNSPLVQRHQHYFNQNAYSQDPQQTTAAAIAWAHYYGWTVQDYNNAYGTQFTPEQYQQYAQQYYQSQGPSSYYGYYDANSYYQQQQIPQSTIPTYLSSTKDPSQPSLPPISTTTTTTTNTTTSIPTTHNQPSTPIEPTKPGVPIDVLDQVGYPFQTSDNPTLLFEKIGQVGEGTYGKVYKARNGKTGKLMALKRIRMKNERDGFPITAMREIKLLQKLKHERIVELQQIMVAKGSVYMVLEYMDHDLSGILGHPNFNFEPAHAKSLVKQMLEGLAYLHHMGILHRDIKGSNLLINNKGELKIADFGLARVFEKKKAHDYSNRVITLWYRPPELLLGTTAYGPAVDIWSVGCIMLEFFTGKAVFNGTDEVSQLECIYKIMGTPSVDNWPTLKELPWFELVKPQGVYPSRFRELYGPLLSPGALELSEALLSMDPINRPTAAEALEFEYFKKESPEPVMPANLLDIHGDWHEFESKQRKRQKATSNNLQTKKREKH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N7H1</accession>
    <name>A0A1C7N7H1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">40S ribosomal protein S15</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">RPS15_1</name>
        <name evidence="5" type="ORF">A0J61_06871</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the universal ribosomal protein uS19 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000436">
        <property type="protein sequence ID" value="OBZ85073.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N7H1"/>
    <dbReference type="STRING" id="101091.A0A1C7N7H1"/>
    <dbReference type="InParanoid" id="A0A1C7N7H1"/>
    <dbReference type="OrthoDB" id="10258210at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022627">
        <property type="term" value="C:cytosolic small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000028">
        <property type="term" value="P:ribosomal small subunit assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.860.10:FF:000002">
        <property type="entry name" value="40S ribosomal protein S15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.860.10">
        <property type="entry name" value="30s Ribosomal Protein S19, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00531">
        <property type="entry name" value="Ribosomal_uS19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002222">
        <property type="entry name" value="Ribosomal_uS19"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005713">
        <property type="entry name" value="Ribosomal_uS19_euk/arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023575">
        <property type="entry name" value="Ribosomal_uS19_SF"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01025">
        <property type="entry name" value="uS19_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11880">
        <property type="entry name" value="RIBOSOMAL PROTEIN S19P FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11880:SF2">
        <property type="entry name" value="SMALL RIBOSOMAL SUBUNIT PROTEIN US19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00203">
        <property type="entry name" value="Ribosomal_S19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002144">
        <property type="entry name" value="Ribosomal_S19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00975">
        <property type="entry name" value="RIBOSOMALS19"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54570">
        <property type="entry name" value="Ribosomal protein S19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 5" id="KW-0689">Ribosomal protein</keyword>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OBZ85073.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="97" mass="10765" checksum="E86AB00F17FFF653" modified="2016-11-30" version="1" fragment="single">LKRKPMGLIKKLRAAKKNAPSGEKPEVVKTHLRNMIIVPEMIGSVIGIYNGKTFNQVEIKPEMTGHYLGEFSITYKPVKHGRPGIGATHSSKFVPLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N7M2</accession>
    <name>A0A1C7N7M2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Phospholipase B1, membrane-associated-like</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_06897</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000438">
        <property type="protein sequence ID" value="OBZ85061.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N7M2"/>
    <dbReference type="InParanoid" id="A0A1C7N7M2"/>
    <dbReference type="OrthoDB" id="10265800at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004620">
        <property type="term" value="F:phospholipase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006644">
        <property type="term" value="P:phospholipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1110">
        <property type="entry name" value="SGNH hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001087">
        <property type="entry name" value="GDSL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038885">
        <property type="entry name" value="PLB1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036514">
        <property type="entry name" value="SGNH_hydro_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21325:SF31">
        <property type="entry name" value="GH22081P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21325">
        <property type="entry name" value="PHOSPHOLIPASE B, PLB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00657">
        <property type="entry name" value="Lipase_GDSL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52266">
        <property type="entry name" value="SGNH hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ85061.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="282" mass="31761" checksum="23566FF2E8525D43" modified="2016-11-30" version="1">MECQWTKPFQYTSISITAGMLAKNTDSDVVDFSTIVEYRGESFTMGGNLGAASVANYIKHFQPDLYGASIGQKPARICKETLFCLDSHHDPDIDQLNAAQSGATSAKLLEQVDYLIKYFGHQTPHAKTWKLINLMIGYNDASVACLTNETVIDFKRNVKKGLDRLIDNTDYAFINLVGLMKYDGIIRLTKKNPNYRKKFKDSLVDISXYECYCCSRPNDGSPNRDELIKGYNRALFEIAEELNQSVLTYVIDTIFGTAPKQVAVVFQPMDTDTSSIPYYAMR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N869</accession>
    <name>A0A1C7N869_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Protein MEMO1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">memo1</name>
        <name evidence="2" type="ORF">A0J61_06625</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the MEMO1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000409">
        <property type="protein sequence ID" value="OBZ85325.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N869"/>
    <dbReference type="FunCoup" id="A0A1C7N869">
        <property type="interactions" value="281"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N869"/>
    <dbReference type="InParanoid" id="A0A1C7N869"/>
    <dbReference type="OrthoDB" id="417112at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd07361">
        <property type="entry name" value="MEMO_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.830.10">
        <property type="entry name" value="LigB-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00055">
        <property type="entry name" value="MEMO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002737">
        <property type="entry name" value="MEMO1_fam"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR04336">
        <property type="entry name" value="AmmeMemoSam_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11060">
        <property type="entry name" value="PROTEIN MEMO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11060:SF0">
        <property type="entry name" value="PROTEIN MEMO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01875">
        <property type="entry name" value="Memo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ85325.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="312" mass="35880" checksum="BAFA4D5CD5D64E4C" modified="2016-11-30" version="1">MKRAATHAGSWYTRHKDSLDHELDTYFEKADINPLKGVRAIIGPHAGLRFSGPTAAYAYKSIDTTGLKRVFILGPSHHAYIDGCSLSKCLAYKTPLGELRLDRQVIEELHQTGHFDFMSETVDHDEHSIEMHLPYVYKIFESLIDDIQIVPILVGSIRHQQEKAYGELLAPYLNDPQNLFIISSDFCHWGTRFNYTYYRPQKDQDPIRLSRHHEALSCPIHESIKDLDLEGIHLLKNLESDKFQAYLTQTRNTICGRHPIGVLMAAIDHLRQKEHLPEPEIKCVHYEQSSQCKEVKDSSVSYASIYFQFKQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N8K2</accession>
    <name>A0A1C7N8K2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_06492</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000394">
        <property type="protein sequence ID" value="OBZ85455.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N8K2"/>
    <dbReference type="InParanoid" id="A0A1C7N8K2"/>
    <dbReference type="OrthoDB" id="3360032at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012068427" evidence="2">
        <location>
            <begin position="16"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="140"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="175"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ85455.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="175" mass="20152" checksum="6B3CCCE92ED50101" modified="2016-11-30" version="1" fragment="single">WTLFVVLYFSYSAQANTEKLILSVEQTPPSLPPCQHQNIPVLTPPYTQLKDSIVPSRNHSVYRLDVQPNSQYEIRISYPAITPADFQLKTIERCQHTNHISYLLEVSANYTGVSRVKDVELTPVEFHLETLYLGFLFYQVYKIVIAMVAVLCLGQFVLLPYLKEKITQVAQQKME</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N8X5</accession>
    <name>A0A1C7N8X5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">PHO85 cyclin-1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">PCL1_2</name>
        <name evidence="2" type="ORF">A0J61_06375</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000382">
        <property type="protein sequence ID" value="OBZ85573.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N8X5"/>
    <dbReference type="STRING" id="101091.A0A1C7N8X5"/>
    <dbReference type="InParanoid" id="A0A1C7N8X5"/>
    <dbReference type="OrthoDB" id="10250320at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000307">
        <property type="term" value="C:cyclin-dependent protein kinase holoenzyme complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016538">
        <property type="term" value="F:cyclin-dependent protein serine/threonine kinase regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019901">
        <property type="term" value="F:protein kinase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd20557">
        <property type="entry name" value="CYCLIN_ScPCL1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.10">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036915">
        <property type="entry name" value="Cyclin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006671">
        <property type="entry name" value="Cyclin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013922">
        <property type="entry name" value="Cyclin_PHO80-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15615">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15615:SF27">
        <property type="entry name" value="PHO85 CYCLIN CLG1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00134">
        <property type="entry name" value="Cyclin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47954">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cyclin N-terminal" evidence="1">
        <location>
            <begin position="27"/>
            <end position="140"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ85573.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="204" mass="22936" checksum="0559684759F0BF0A" modified="2016-11-30" version="1">MSTINTTQIISRNPEALSAFTTLTVNSLLSCTNQTQWKLLPPLNEFISNLYHKKRLSCAVKAFALIYLLRLKSKLPVNARGGPDTPYRLFLAALLTSSKYLSESGTGLTSTQLASLVHHYSAREINRMERSFLGLLRYDLWVSNKDIQSFIEHYGHFIQIDIHHVYLPLHGVSVQNKMRCSLLDAHDTQETSASSNGVISNTNI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-06-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N8Y2</accession>
    <name>A0A1C7N8Y2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_06392</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000383">
        <property type="protein sequence ID" value="OBZ85560.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N8Y2"/>
    <dbReference type="InParanoid" id="A0A1C7N8Y2"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ85560.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="78" mass="9380" checksum="3107F5B8A1A43BFD" modified="2016-11-30" version="1">MVVPSRPPQQVPSNHSHYDQSLYYSQTNLQQQRMMMQQQDYEQRQLLDQQAHNHVHLPMIRNHFYSQAAQQNQNNSCK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N979</accession>
    <name>A0A1C7N979_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">O-acyltransferase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="primary">DGAT1</name>
        <name evidence="15" type="ORF">A0J61_06264</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Sterol O-acyltransferase that catalyzes the formation of stery esters.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2">Lipid metabolism.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 11">Endoplasmic reticulum membrane</location>
            <topology evidence="1 11">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 11">Belongs to the membrane-bound acyltransferase family. Sterol o-acyltransferase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000370">
        <property type="protein sequence ID" value="OBZ85685.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N979"/>
    <dbReference type="STRING" id="101091.A0A1C7N979"/>
    <dbReference type="InParanoid" id="A0A1C7N979"/>
    <dbReference type="OrthoDB" id="10039049at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004144">
        <property type="term" value="F:diacylglycerol O-acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019432">
        <property type="term" value="P:triglyceride biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004299">
        <property type="entry name" value="MBOAT_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014371">
        <property type="entry name" value="Oat_ACAT_DAG_ARE"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10408:SF7">
        <property type="entry name" value="DIACYLGLYCEROL O-ACYLTRANSFERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10408">
        <property type="entry name" value="STEROL O-ACYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03062">
        <property type="entry name" value="MBOAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000439">
        <property type="entry name" value="Oat_ACAT_DAG_ARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 11 15" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="6 11" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="8 11 14" id="KW-0472">Membrane</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 11 15" id="KW-0808">Transferase</keyword>
    <keyword evidence="5 14" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 14" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="84"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="124"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="168"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="196"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="335"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="409"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="433"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="464"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="13">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="active site" evidence="12">
        <location>
            <position position="419"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023568"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRNR" id="PIRNR000439"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR000439-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="OBZ85685.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="497" mass="56871" checksum="66AFEBF901CEB34E" modified="2016-11-30" version="1">MATNFRKRPLKVVTDSEDDQSDSRQRRDLHLTSRRVSTIAEEGKEDKKKTNSQIYNDYCHTLPIHTITKASVLSKEAPPENYSGFLRLGMLVLGASNIRLIIENWMKYGLLIGFPHSYIPLKDYLFFVVAWLSVPFSLSISLVVEYGMGKLATKAKEGNPEYIKKLALLERVVTVSHICHLLFLLTYPSYIVYTKIYHPLVGSSVLVICLVSFLKLTSYALVNHELRQTYVTGKPGSEEFYTKDVAYPNNVSANNLLYFFFAPTLCYQPSYPRTPKFRKTFFLKRVGELCTCLLMMYVLAEQYAKPTLANSIQALEDKKLVTIVERVLKLSTTAVVIWLLMFYALFHAFLNALSELLCFGDRTFYLAWWNSGNLATYWRLWNRPVYLFFKRHVYIPAVQRGVPPALCQLWVFFVSAVLHEVLVGIPTHSLTGFAFWGMLGQIPLIALTHSIEKWRGKGTSLGNTIFWIVFCVVGQPTIALLYYYQWTVTHKVAASTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N9S3</accession>
    <name>A0A1C7N9S3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Non-histone chromosomal protein 6</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">nhp-1</name>
        <name evidence="5" type="ORF">A0J61_06123</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000354">
        <property type="protein sequence ID" value="OBZ85827.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N9S3"/>
    <dbReference type="STRING" id="101091.A0A1C7N9S3"/>
    <dbReference type="InParanoid" id="A0A1C7N9S3"/>
    <dbReference type="OrthoDB" id="1919336at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01389">
        <property type="entry name" value="HMG-box_ROX1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00084">
        <property type="entry name" value="HMG-box_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.30.10">
        <property type="entry name" value="High mobility group box domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009071">
        <property type="entry name" value="HMG_box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036910">
        <property type="entry name" value="HMG_box_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050342">
        <property type="entry name" value="HMGB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48112">
        <property type="entry name" value="HIGH MOBILITY GROUP PROTEIN DSP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48112:SF15">
        <property type="entry name" value="HMG BOX DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00505">
        <property type="entry name" value="HMG_box"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00398">
        <property type="entry name" value="HMG"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47095">
        <property type="entry name" value="HMG-box"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50118">
        <property type="entry name" value="HMG_BOX_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HMG box" evidence="4">
        <location>
            <begin position="135"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="domain" description="HMG box" evidence="4">
        <location>
            <begin position="245"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="HMG box" evidence="2">
        <location>
            <begin position="135"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="HMG box" evidence="2">
        <location>
            <begin position="245"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="34"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="215"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="41"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="229"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="367"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OBZ85827.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="367" mass="41889" checksum="2D1E9F57BCB1E221" modified="2016-11-30" version="1" fragment="single">MGLTLNSIDNLSGNIEYSLQQYAAITQAQLLGTPPLRQHDSPQTQPTVLQQSRSDAQPSSSQQEGLPMQDPNAFNLAYQSFSPLVRMMPPQLHQPTLASTKELSTTPINTIPSSSKIQQTLDAAENISSEAPTRVTRPPNAYLLFNKEMRKILKNQDPSMKVADISKEVGFRWKNMSKEQKEHYITQANKLKEEQKALHPNAMYIRRSRAELVEAGRLTKHASQDSTLKRKKRSKKKRNKNSSTPKHPLSAYMWYLTEVRPETMRHFPGSNVGQISKLCADRWNSMTEEARLPWKTKAQVDKERYAREMQIYAIQNDHTLGRGTRQKYRTAALKQANEISLVDPLLYKTMQPQQQLLLHTQQLSPPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N9Y3</accession>
    <name>A0A1C7N9Y3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_06472</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000392">
        <property type="protein sequence ID" value="OBZ85479.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N9Y3"/>
    <dbReference type="InParanoid" id="A0A1C7N9Y3"/>
    <dbReference type="OrthoDB" id="2384506at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="77"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="77"/>
            <end position="89"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ85479.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="100" mass="11154" checksum="32E33A660F340FC8" modified="2016-11-30" version="1">MPYSFALPKFSGSTLEPQSEPIMLYEPQYYEKNAGRAQMSLVPTRPTPPLKRAFKPPHIVIPEPNFGGMQSNNTSFSAWSFKDGSTSTPALWDSPSFPRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NAG5</accession>
    <name>A0A1C7NAG5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Caseinolytic peptidase B</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">Clpb</name>
        <name evidence="7" type="ORF">A0J61_05919</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000335">
        <property type="protein sequence ID" value="OBZ86031.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NAG5"/>
    <dbReference type="STRING" id="101091.A0A1C7NAG5"/>
    <dbReference type="InParanoid" id="A0A1C7NAG5"/>
    <dbReference type="OrthoDB" id="18170at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034605">
        <property type="term" value="P:cellular response to heat"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd19499">
        <property type="entry name" value="RecA-like_ClpB_Hsp104-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019489">
        <property type="entry name" value="Clp_ATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001270">
        <property type="entry name" value="ClpA/B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050130">
        <property type="entry name" value="ClpA_ClpB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11638">
        <property type="entry name" value="ATP-DEPENDENT CLP PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11638:SF93">
        <property type="entry name" value="MITOCHONDRIAL DISAGGREGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07724">
        <property type="entry name" value="AAA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00023">
        <property type="entry name" value="Ank"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10431">
        <property type="entry name" value="ClpB_D2-small"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00300">
        <property type="entry name" value="CLPPROTEASEA"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM01086">
        <property type="entry name" value="ClpB_D2-small"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="80"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="139"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="domain" description="AAA+ ATPase" evidence="5">
        <location>
            <begin position="267"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="domain" description="Clp ATPase C-terminal" evidence="6">
        <location>
            <begin position="474"/>
            <end position="564"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="201"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="568"/>
            <end position="589"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="568"/>
            <end position="579"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM01086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OBZ86031.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="589" mass="66905" checksum="3EA85C07AFF73DA2" modified="2016-11-30" version="1">MATVSVATQQPKTRYSSFLLKATSVTAVSIAALALTNTKVFALEANECDAMCKAIIQNDIKTLKKLADDPNFTPNVYHRYGWTPLHVAVIQDNEVMVKFLLEKGADPNLQDQYYPRSHQAANIRQVDFSEDLLPYRDYREYTALHYAVIVCNPKIVKMLLDHLADPLARNSNGLTPREYLYYVERFTGEQNTEIEELLHKKETSYPKDKAEHDERQRKAQLQREKEYRKKHPLEDALKARIVGQLGPVHALASAIRRKQNGWHDEEHPLVFMFCGPSGVGKTELAKALAQHLHGKQIDKGFVRIDMSEFQHKHDVSRFIGSPPGYVGYEEGGQLTERLKECPNAVVLLDEVEKAHPDVLTVMLQLFDEGRITDGKGTTVECKDAIFIMTSNLAQHEIADEAELLRLEASVASDVQLTGAATVMEPKKNESTTADGLISLSRQFIERTIYPILYDHFRRDEFLGRINEVLFFLPFSEEELREITSRELSRWAEKARNRHNITVTWDPEVVDVLAKGYNIRYGARSIKYEVERRIVNLIAKANENDDVLDGGRVHVVVEKAGEHRIPKIEIPEKGGDDGKKSGVGSWFSKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NAI2</accession>
    <name>A0A1C7NAI2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Zinc knuckle domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_05903</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000333">
        <property type="protein sequence ID" value="OBZ86051.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="InParanoid" id="A0A1C7NAI2"/>
    <dbReference type="OrthoDB" id="2299372at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.60.10">
        <property type="entry name" value="Zinc finger, CCHC-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="89"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="29"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="99"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ86051.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="108" mass="12002" checksum="9A9692BD65818AB4" modified="2016-11-30" version="1" fragment="single">MSNSIQTCASCNQSGHSRRSHRDCPLXPANNQSESVPETTSAMDIDNALEELNEIQPDMQLRCPSCHQVGHLRRTSRLCPLNNRATEDNTSMAMQTDVLPERHNLGGM</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NAM2</accession>
    <name>A0A1C7NAM2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Acetyl-coenzyme A synthetase</fullName>
            <ecNumber evidence="5">6.2.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">facA_0</name>
        <name evidence="9" type="ORF">A0J61_05856</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11 5">
            <text>acetate + ATP + CoA = acetyl-CoA + AMP + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:23176"/>
            <dbReference type="ChEBI" id="CHEBI:30089"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.2.1.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the ATP-dependent AMP-binding enzyme family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.2.1.1" evidence="5"/>
    <dbReference type="EMBL" id="LUGH01000329">
        <property type="protein sequence ID" value="OBZ86091.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NAM2"/>
    <dbReference type="FunCoup" id="A0A1C7NAM2">
        <property type="interactions" value="548"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NAM2"/>
    <dbReference type="InParanoid" id="A0A1C7NAM2"/>
    <dbReference type="OrthoDB" id="1706066at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003987">
        <property type="term" value="F:acetate-CoA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016208">
        <property type="term" value="F:AMP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019427">
        <property type="term" value="P:acetyl-CoA biosynthetic process from acetate"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05966">
        <property type="entry name" value="ACS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.300.30:FF:000004">
        <property type="entry name" value="Acetyl-coenzyme A synthetase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.12780:FF:000001">
        <property type="entry name" value="Acetyl-coenzyme A synthetase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="entry name" value="N-terminal domain of ligase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011904">
        <property type="entry name" value="Ac_CoA_lig"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032387">
        <property type="entry name" value="ACAS_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025110">
        <property type="entry name" value="AMP-bd_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_synth/lig_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02188">
        <property type="entry name" value="Ac_CoA_lig_AcsA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF001208">
        <property type="entry name" value="PRK00174.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24095">
        <property type="entry name" value="ACETYL-COENZYME A SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24095:SF14">
        <property type="entry name" value="ACETYL-COENZYME A SYNTHETASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16177">
        <property type="entry name" value="ACAS_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13193">
        <property type="entry name" value="AMP-binding_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56801">
        <property type="entry name" value="Acetyl-CoA synthetase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 5" id="KW-0436">Ligase</keyword>
    <keyword evidence="3 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Acetyl-coenzyme A synthetase N-terminal" evidence="8">
        <location>
            <begin position="33"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="domain" description="AMP-dependent synthetase/ligase" evidence="6">
        <location>
            <begin position="91"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="domain" description="AMP-binding enzyme C-terminal" evidence="7">
        <location>
            <begin position="539"/>
            <end position="617"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU361147"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF13193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF16177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OBZ86091.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="658" mass="72633" checksum="E0F10D0886FF9F32" modified="2016-11-30" version="1">MTVEAPQSLYPVPERLLNGTNLPKPFISSFEEYKTKWEESVKNPDQFFGKLANELLTWSKPFETVRSGSFEEGDIAWFLEGELNVSVNCIDRHALATPDKVAIIHEGDEPENVRYITYRELLQQVCRVANTLKALDVRKGDNVAIYMPMVPEAVYAMLACARIGAVHSVVFAGFSSDSLRDRINDCGARVVLTADEGRRGGKNIATKRIVDEALKSAPTVEHVLVLRRTGSDVPITPGRDLYWHEEMAKARPYCPPTSMNAEDPLFLLYTSGSTGTPKGVVHTTGGYLLGAASTVKYIFDYHEGDIHACMADIGWITGHTYIVYGPLALGATTVLFESTPTYPTPSRFWELVAKHRVTQFYTAPTAIRALRRLGDKWVDGVDLSSLRVIGSVGEPINPEAWLWYNEKVGKGQCAVVDTYWQTETGSIIVTPLPGATATKPGSATFPFFGINPVILDPVSGKELEGNNVSGVLAISQPWPSIARSVYNNHHRYLDTYLKPYRGYYFTGDGARRDQDGYIFIEGRVDDVINVSGHRLSTAEIESALILHHSVAEAAVVGGQDDLTGQCIHAYCTLKPNIDDSEGLDKELALQVRKVIGPFATPKRIYVVNDLPKTRSGKIMRRILRKIVNGEQDSLGDISTLAEPAVVAHLIERVHGKKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NAP3</accession>
    <name>A0A1C7NAP3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Nudix hydrolase 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">ndx-3</name>
        <name evidence="8" type="ORF">A0J61_05844</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000328">
        <property type="protein sequence ID" value="OBZ86100.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NAP3"/>
    <dbReference type="FunCoup" id="A0A1C7NAP3">
        <property type="interactions" value="17"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NAP3"/>
    <dbReference type="InParanoid" id="A0A1C7NAP3"/>
    <dbReference type="OrthoDB" id="206213at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010945">
        <property type="term" value="F:coenzyme A diphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd03426">
        <property type="entry name" value="NUDIX_CoAse_Nudt7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.79.10">
        <property type="entry name" value="Nucleoside Triphosphate Pyrophosphohydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045121">
        <property type="entry name" value="CoAse"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015797">
        <property type="entry name" value="NUDIX_hydrolase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000086">
        <property type="entry name" value="NUDIX_hydrolase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12992:SF11">
        <property type="entry name" value="MITOCHONDRIAL COENZYME A DIPHOSPHATASE NUDT8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12992">
        <property type="entry name" value="NUDIX HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00293">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55811">
        <property type="entry name" value="Nudix"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51462">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6" id="KW-0464">Manganese</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nudix hydrolase" evidence="7">
        <location>
            <begin position="36"/>
            <end position="170"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OBZ86100.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="207" mass="23930" checksum="10F09D7A7A43C6EF" modified="2016-11-30" version="1">MLSRTAPIVFDTTTLSLFSRRLLNYPRFKLSYKPDVKEAAVLVPLCIDQGKPSVLFTVRNMNMRTHRGEISFPGGKTDDTDPSTEYTALRETHEEIGIQPKSIDILGRYSALPNKTGSLRVHPYVGFIKDQVDLNKFNRDEVSSVFTLPVDYLIRPDIREIRQFRDSKQKYTVYRVPEHIEGDKEIWGLTSYILDGVFRKMIPEHYS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NAX6</accession>
    <name>A0A1C7NAX6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Protein max</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">max</name>
        <name evidence="9" type="ORF">A0J61_05833</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000327">
        <property type="protein sequence ID" value="OBZ86118.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NAX6"/>
    <dbReference type="STRING" id="101091.A0A1C7NAX6"/>
    <dbReference type="InParanoid" id="A0A1C7NAX6"/>
    <dbReference type="OrthoDB" id="5778525at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.280.10">
        <property type="entry name" value="Helix-loop-helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011598">
        <property type="entry name" value="bHLH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036638">
        <property type="entry name" value="HLH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052207">
        <property type="entry name" value="Max-like/E-box_TFs"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15741">
        <property type="entry name" value="BASIC HELIX-LOOP-HELIX ZIP TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15741:SF27">
        <property type="entry name" value="TRANSCRIPTION FACTOR AP-4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00010">
        <property type="entry name" value="HLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00353">
        <property type="entry name" value="HLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47459">
        <property type="entry name" value="HLH, helix-loop-helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50888">
        <property type="entry name" value="BHLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="BHLH" evidence="8">
        <location>
            <begin position="130"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="102"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="178"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="10"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="105"/>
            <end position="134"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50888"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OBZ86118.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="343" mass="38567" checksum="79F87633F3DA027C" modified="2016-11-30" version="1">MEYDPANKASSVTSISTTSSSLWDPLPSLYTGRADSVSSAYDELEPFEENKAIVSVLNDSLNPTYLYDKQENPVLMDQQSLLNSFLEEEKLLILNEPSLHCHGKRPSELDSKEPKKPKQEDSRELLSEDQKRANHIASEQKRRNIIRGGFRELTEIIPTLKNINNSKSTILFKSVDYIKQLDRRNKALKEKLASLQHRAQQKALKKSNPNGLMAHKHQLELLQEQLRLQQALLNKHNIHLYPTSHPTATGGYHSISIPAMDDTPVTSTHNSPTLTHASLPVNNHPVSSHAALVMPASLDEWQHAGISSFTIPADESDKQSTFRERLLSSGKLDHLRPSMHSTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NBS2</accession>
    <name>A0A1C7NBS2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Demethylmenaquinone methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">menG_1</name>
        <name evidence="2" type="ORF">A0J61_05749</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000320">
        <property type="protein sequence ID" value="OBZ86199.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NBS2"/>
    <dbReference type="FunCoup" id="A0A1C7NBS2">
        <property type="interactions" value="432"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NBS2"/>
    <dbReference type="InParanoid" id="A0A1C7NBS2"/>
    <dbReference type="OrthoDB" id="2013972at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041698">
        <property type="entry name" value="Methyltransf_25"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43591:SF24">
        <property type="entry name" value="2-METHOXY-6-POLYPRENYL-1,4-BENZOQUINOL METHYLASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43591">
        <property type="entry name" value="METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13649">
        <property type="entry name" value="Methyltransf_25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransferase" evidence="1">
        <location>
            <begin position="88"/>
            <end position="178"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ86199.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="307" mass="35365" checksum="593B17A76D1C8AC5" modified="2016-11-30" version="1">MGNKLSSNRNLQDIYTINKQLSENVSYRSEDSQTETLAQTLTFITDTAQQDEERMNTHHFALKEMFGSNFLKTIEGDVDFNSSSTKTLDIGCGAGTWLMDMATEFPTAKFVGIDKEALFPQIIRPANVEFYEGDVRNGLPFEDNYFDLVQIRLFLLAFDMSDWEGCLKEVYRVLKPGGYIQWTEPKLMDRGDEVVTEFSSRVHDMLVSRNQDPEIIEHQVDMLKQHGFVPKEKITKAIPLSNHPLSKEFMFIINISLDYCKPIIVEMYKHTSDEQFLKFKKSILVHRQRSSEATWSCVVGQKPTELS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NBW3</accession>
    <name>A0A1C7NBW3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">tRNA (guanine(9)-N1)-methyltransferase</fullName>
            <ecNumber evidence="1">2.1.1.221</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">tRNA methyltransferase 10</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">tRNA(m1G9)-methyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="primary">trm10_1</name>
        <name evidence="10" type="ORF">A0J61_05400</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>guanosine(9) in tRNA + S-adenosyl-L-methionine = N(1)-methylguanosine(9) in tRNA + S-adenosyl-L-homocysteine + H(+)</text>
            <dbReference type="Rhea" id="RHEA:43156"/>
            <dbReference type="Rhea" id="RHEA-COMP:10367"/>
            <dbReference type="Rhea" id="RHEA-COMP:10368"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:73542"/>
            <dbReference type="ChEBI" id="CHEBI:74269"/>
            <dbReference type="EC" id="2.1.1.221"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.221" evidence="1"/>
    <dbReference type="EMBL" id="LUGH01000290">
        <property type="protein sequence ID" value="OBZ86551.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NBW3"/>
    <dbReference type="FunCoup" id="A0A1C7NBW3">
        <property type="interactions" value="746"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NBW3"/>
    <dbReference type="InParanoid" id="A0A1C7NBW3"/>
    <dbReference type="OrthoDB" id="278300at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052905">
        <property type="term" value="F:tRNA (guanosine(9)-N1)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002939">
        <property type="term" value="P:tRNA N1-guanine methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd18089">
        <property type="entry name" value="SPOUT_Trm10-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1280.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028564">
        <property type="entry name" value="MT_TRM10-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038459">
        <property type="entry name" value="MT_TRM10-typ_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007356">
        <property type="entry name" value="tRNA_m1G_MeTrfase_euk"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13563">
        <property type="entry name" value="TRNA (GUANINE-9-) METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13563:SF13">
        <property type="entry name" value="TRNA METHYLTRANSFERASE 10 HOMOLOG A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51675">
        <property type="entry name" value="SAM_MT_TRM10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 10" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="4 10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="SAM-dependent MTase TRM10-type" evidence="9">
        <location>
            <begin position="87"/>
            <end position="277"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012797"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00020451"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00031792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00032166"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00048434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51675"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OBZ86551.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="282" mass="32970" checksum="ECFDE8AEB69D90A5" modified="2016-11-30" version="1">MEELADISIIDNDTCHDTLRTFQGLEYDINDPKFQGLSKSAMKRLIRHEQWAETKEARKSYQREKFRQKRKEKRQLVREGVLEKPVSKKKLAHQSQQLNMGLILDCGFSDLMTEKELYSLVSQLSYTYGRNKIAPKAMKMCLTSFDTPLEQMLDSKLPDWTHWQLDRKHESYMEHYDPSTLVYLTADSTCVIDRLEEGKNYIVGGIVDKNRYKNLCYDKANQQAIQTAQLPISDYLSLSTRKVLTVNQVCEIMLKWNELGDWQEAFLQVIPERKLKDATVIT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NBW5</accession>
    <name>A0A1C7NBW5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">DUF202 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">A0J61_05333</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000285">
        <property type="protein sequence ID" value="OBZ86617.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NBW5"/>
    <dbReference type="InParanoid" id="A0A1C7NBW5"/>
    <dbReference type="OrthoDB" id="199599at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003807">
        <property type="entry name" value="DUF202"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02656">
        <property type="entry name" value="DUF202"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="DUF202" evidence="5">
        <location>
            <begin position="40"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF02656"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OBZ86617.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="81" mass="9454" checksum="C139460D82B9279B" modified="2016-11-30" version="1">MDVELNAPEQFTLCNNEKCSTKFKYLDYSIHTVVDGPDPRDHLANERNLLTWIRTGTTLALIDYRIHDTIGFTRKEFCSFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NCE4</accession>
    <name>A0A1C7NCE4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">uracil phosphoribosyltransferase</fullName>
            <ecNumber evidence="4">2.4.2.9</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">upp</name>
        <name evidence="11" type="ORF">A0J61_06931</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Pyrimidine metabolism; UMP biosynthesis via salvage pathway; UMP from uracil: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the UPRTase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.2.9" evidence="4"/>
    <dbReference type="EMBL" id="LUGH01000442">
        <property type="protein sequence ID" value="OBZ85024.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="FunCoup" id="A0A1C7NCE4">
        <property type="interactions" value="105"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NCE4"/>
    <dbReference type="InParanoid" id="A0A1C7NCE4"/>
    <dbReference type="OrthoDB" id="10257085at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004845">
        <property type="term" value="F:uracil phosphoribosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd06223">
        <property type="entry name" value="PRTases_typeI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2020">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029057">
        <property type="entry name" value="PRTase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000836">
        <property type="entry name" value="PRTase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050054">
        <property type="entry name" value="UPRTase/APRTase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF001097">
        <property type="entry name" value="PRK00129.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32315">
        <property type="entry name" value="ADENINE PHOSPHORIBOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32315:SF4">
        <property type="entry name" value="URACIL PHOSPHORIBOSYLTRANSFERASE, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14681">
        <property type="entry name" value="UPRTase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53271">
        <property type="entry name" value="PRTase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0021">Allosteric enzyme</keyword>
    <keyword evidence="6 11" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="9" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 11" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Phosphoribosyltransferase" evidence="10">
        <location>
            <begin position="11"/>
            <end position="215"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011894"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF14681"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="OBZ85024.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="217" mass="23761" checksum="C751B6F542A6E8EA" modified="2016-11-30" version="1">MSMTHHEFLHVSQHPIVAAKLSQLRDGKQNSKTVRELTRDLSILLGYEASADTKLKKGATGSTSHGSYQMDEISGKVGLIPVLRSGLGFVDGFLSLFPEAPVYHLGIYREKVSHQPVEYYNKLPDSPTVETCYVLDPVIATGNTAIATINLLKEWXLSGSRIKFVSIISSEQGLAQLQKEHPDIHIYTAAVDNALDSDGYISPGIGDSGDRLWNTLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NCJ2</accession>
    <name>A0A1C7NCJ2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Ricin B lectin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_05465</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000295">
        <property type="protein sequence ID" value="OBZ86489.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NCJ2"/>
    <dbReference type="STRING" id="101091.A0A1C7NCJ2"/>
    <dbReference type="InParanoid" id="A0A1C7NCJ2"/>
    <dbReference type="OrthoDB" id="9895617at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd23454">
        <property type="entry name" value="beta-trefoil_Ricin_GllA-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.80.10.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022234">
        <property type="entry name" value="DUF3759"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035992">
        <property type="entry name" value="Ricin_B-like_lectins"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37450">
        <property type="entry name" value="CIPC PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37450:SF1">
        <property type="entry name" value="CIPC PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12585">
        <property type="entry name" value="DUF3759"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50370">
        <property type="entry name" value="Ricin B-like lectins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ86489.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="304" mass="35289" checksum="4D575ECB7763352E" modified="2016-11-30" version="1">MTVPEDTFPIGYFYIVSKMNGLVLDIRDPENAAVRSKIVMEPKKPVSPERDSQLWIHQDGFLTNKASGLVLDIDRAESFIAIFTRENRLYLDQMKESEAADDQRFGYDSENGYIYALSNPDIVFDILHKEEAEDARVIVHKRKPLEEAENQLWTIELADPPRKIDPEDEEEDDSKRERFKAWFGNWRGWGHSKKREVLSESELKEANEKVYHEKKHSATYELIAAAVAYQAVNMWEKKQEEEGNEVHHGTAKKMVAAFAAKELVKILQERDDAEEVENDEQKKKWIEKMTTSAASNYFDQKHGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NDB4</accession>
    <name>A0A1C7NDB4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">pectinesterase</fullName>
            <ecNumber evidence="3">3.1.1.11</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">PMEU1_0</name>
        <name evidence="8" type="ORF">A0J61_04899</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Glycan metabolism; pectin degradation; 2-dehydro-3-deoxy-D-gluconate from pectin: step 1/5.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the pectinesterase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.11" evidence="3"/>
    <dbReference type="EMBL" id="LUGH01000250">
        <property type="protein sequence ID" value="OBZ87065.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NDB4"/>
    <dbReference type="InParanoid" id="A0A1C7NDB4"/>
    <dbReference type="OrthoDB" id="1546079at2759"/>
    <dbReference type="UniPathway" id="UPA00545">
        <property type="reaction ID" value="UER00823"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030599">
        <property type="term" value="F:pectinesterase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042545">
        <property type="term" value="P:cell wall modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045490">
        <property type="term" value="P:pectin catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.20.10">
        <property type="entry name" value="Single-stranded right-handed beta-helix, Pectin lyase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012334">
        <property type="entry name" value="Pectin_lyas_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011050">
        <property type="entry name" value="Pectin_lyase_fold/virulence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000070">
        <property type="entry name" value="Pectinesterase_cat"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31321">
        <property type="entry name" value="ACYL-COA THIOESTER HYDROLASE YBHC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31321:SF58">
        <property type="entry name" value="METHYLESTERASE, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01095">
        <property type="entry name" value="Pectinesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51126">
        <property type="entry name" value="Pectin lyase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0063">Aspartyl esterase</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5011112281" description="pectinesterase" evidence="6">
        <location>
            <begin position="21"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="domain" description="Pectinesterase catalytic" evidence="7">
        <location>
            <begin position="27"/>
            <end position="303"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008891"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01095"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OBZ87065.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="332" mass="35439" checksum="3D302FE0C00BA168" modified="2016-11-30" version="1">MKFSLNILFAFLTYTSLALAATIDVCSSCQYKTISAALASIPSGSTSYTINISPGTYNERLNINRSNVVLTKNGSGNVVVQYAIAXNTQDKNSIATEKAVVSITGSNVRFYDITIANTYKQTTNIATIAVSIQGQQVGFYRCSIYGFQDTLLVNANATSYFKSCYIEGSVDFIYGFGTGYFQSCTIASNAVGFITAHNRVSSSAGGGLYFNSCTTKATVPSGPIAKTANPSLSYTSSTNTASTSYLGRPWSQYARVIFIYSTIDAHIKQAGWSEWSATDPRTSHILFGEFGNKGARGSLTGRAFVTKLSQSQANGYSAGGVFGSTSWIDTSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NDD9</accession>
    <name>A0A1C7NDD9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 11">NEDD8-activating enzyme E1 catalytic subunit</fullName>
            <ecNumber evidence="8 11">6.2.1.64</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">uba3</name>
        <name evidence="14" type="ORF">A0J61_04863</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Catalytic subunit of the dimeric E1 enzyme, which activates NEDD8.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9 11">
            <text>ATP + [NEDD8 protein] + [E1 NEDD8-activating enzyme]-L-cysteine = AMP + diphosphate + [E1 NEDD8-activating enzyme]-S-[NEDD8 protein]-yl-L-cysteine.</text>
            <dbReference type="EC" id="6.2.1.64"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 11">Protein modification; protein neddylation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the ubiquitin-activating E1 family. UBA3 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.2.1.64" evidence="8 11"/>
    <dbReference type="EMBL" id="LUGH01000248">
        <property type="protein sequence ID" value="OBZ87091.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NDD9"/>
    <dbReference type="FunCoup" id="A0A1C7NDD9">
        <property type="interactions" value="1245"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NDD9"/>
    <dbReference type="InParanoid" id="A0A1C7NDD9"/>
    <dbReference type="OrthoDB" id="10255449at2759"/>
    <dbReference type="UniPathway" id="UPA00885"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019781">
        <property type="term" value="F:NEDD8 activating enzyme activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045116">
        <property type="term" value="P:protein neddylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01488">
        <property type="entry name" value="Uba3_RUB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.520:FF:000001">
        <property type="entry name" value="NEDD8-activating enzyme E1 catalytic subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.50.50.80:FF:000002">
        <property type="entry name" value="SUMO-activating enzyme subunit 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.290.20:FF:000003">
        <property type="entry name" value="Ubiquitin-activating enzyme E1 C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.520">
        <property type="entry name" value="Ubiquitin activating enzymes (Uba3). Chain: B, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.290.20">
        <property type="entry name" value="Ubiquitin-like 2 activating enzyme e1b. Chain: B, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014929">
        <property type="entry name" value="E2-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045886">
        <property type="entry name" value="ThiF/MoeB/HesA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000594">
        <property type="entry name" value="ThiF_NAD_FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023318">
        <property type="entry name" value="Ub_act_enz_dom_a_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030468">
        <property type="entry name" value="Uba3_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035985">
        <property type="entry name" value="Ubiquitin-activating_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033127">
        <property type="entry name" value="UBQ-activ_enz_E1_Cys_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10953:SF6">
        <property type="entry name" value="NEDD8-ACTIVATING ENZYME E1 CATALYTIC SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10953">
        <property type="entry name" value="UBIQUITIN-ACTIVATING ENZYME E1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08825">
        <property type="entry name" value="E2_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00899">
        <property type="entry name" value="ThiF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01181">
        <property type="entry name" value="E2_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69572">
        <property type="entry name" value="Activating enzymes of the ubiquitin-like proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00865">
        <property type="entry name" value="UBIQUITIN_ACTIVAT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 11" id="KW-0436">Ligase</keyword>
    <keyword evidence="5 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 11" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="E2 binding" evidence="13">
        <location>
            <begin position="369"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="active site" description="Glycyl thioester intermediate" evidence="10">
        <location>
            <position position="235"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006310"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00015203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023624"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00024626"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10132"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU368009"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="SMART" id="SM01181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="OBZ87091.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="453" mass="50737" checksum="E0F6EB6B7FC9D800" modified="2016-11-30" version="1">MDSVKRQEHSMTIPDSKRQRTLSTASDEEMTTPVSQTDRSDVDMTELEQEDVEKGIIGSLNSPKILEALEKCKILVIGAGGLGCEILKNLALTGFKHLHVIDMDTIDLSNLNRQFLFRKKDIGQSKAIVAAKFVMSRVPGVEVVPYFGKIQDKDEDYYRQFQIVICGLDSVEARRWINAKLVDMVDEDDMESWKPLIDGGTEGFKGQARVILPTMSSCYECSLDMFNKPTTFPICTIANTPRLPEHCIEWASVLEWPRVWGDKKYDTDNPEHINWLYQQAEARAQKFNITGVTYSLTQGVVKNIIPAIASTNAVIAASCCNEAFKLATGCAPHLNNYMMYTGDAGIYTYTFEHQKKPECPVCGSETSIAELKPTMTVEELIEWLGEKPDAQLKKPSLRTATASLYMQAPKALEQATRPNLTKSVSELVQEGEYITVTDASLPVSLQLRVKWIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NDW9</accession>
    <name>A0A1C7NDW9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Heat shock protein 12A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">HSPA12A_0</name>
        <name evidence="3" type="ORF">A0J61_06385</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000383">
        <property type="protein sequence ID" value="OBZ85564.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NDW9"/>
    <dbReference type="STRING" id="101091.A0A1C7NDW9"/>
    <dbReference type="InParanoid" id="A0A1C7NDW9"/>
    <dbReference type="OrthoDB" id="2963168at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd10229">
        <property type="entry name" value="ASKHA_NBD_HSP70_HSPA12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.640.10">
        <property type="entry name" value="Actin, Chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013126">
        <property type="entry name" value="Hsp_70_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14187">
        <property type="entry name" value="ALPHA KINASE/ELONGATION FACTOR 2 KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14187:SF5">
        <property type="entry name" value="HEAT SHOCK 70 KDA PROTEIN 12A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00012">
        <property type="entry name" value="HSP70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0346">Stress response</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ85564.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="569" mass="64485" checksum="3A2E236BE28A2AB6" modified="2016-11-30" version="1">MTSNRDNYKLVIAYDFGTTFSGASYAFTHNTTPEVFDIQKWPQKGGNFYPKTPTISAYKRSEPSKMIEWGHAAKKLMLKPQTAKENIILTNFKLNLDETLHRGVAENHRSAVSNIADYLRALHQYVLKDVTRGFAKNYDPDTFCYCLTVPAMWSDSAKYAMRRAAIMAGLIKSDDPQDRLVLISEPEAAALYCERMCEQVNLKKGDRMMICDAGGGTVDLIVFEVISDHIQSNHRLKEVTKGMGESCGSVFLDYNFRAFIMDKLGEQASQLPAAAMQNLMDQFVDNIKPEFDGLDDQYLSLSASIDLNQLNTEEDCLDEGTMILRAEELKEKIFEPVVQRVLSLIEKQYSQIPDQSLACLFLVGGFGSSNYLYQRIQEVFENKIHQILCPPRASMAVVRGAVYFGLNPRVIKSRVSRRTYGINAGLPFDERLDPISSRIIRPDGSVRCTTRFLTFVKKGDVIPVDHCIREKMFVYYGLMKATDIMLYATEEDEEPRYFDHPGVKQVASISVPIPKLSHVAHGERIGYTVRMYFGLTEIRMEADFGVGTVHKVHCNFDAVDRYEDDETSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NE19</accession>
    <name>A0A1C7NE19_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">tRNA-intron lyase</fullName>
            <ecNumber evidence="2">4.6.1.16</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">TSEN2</name>
        <name evidence="5" type="ORF">A0J61_04604</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>pretRNA = a 3'-half-tRNA molecule with a 5'-OH end + a 5'-half-tRNA molecule with a 2',3'-cyclic phosphate end + an intron with a 2',3'-cyclic phosphate and a 5'-hydroxyl terminus.</text>
            <dbReference type="EC" id="4.6.1.16"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the tRNA-intron endonuclease family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.6.1.16" evidence="2"/>
    <dbReference type="EMBL" id="LUGH01000229">
        <property type="protein sequence ID" value="OBZ87342.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NE19"/>
    <dbReference type="STRING" id="101091.A0A1C7NE19"/>
    <dbReference type="InParanoid" id="A0A1C7NE19"/>
    <dbReference type="OrthoDB" id="10249562at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000214">
        <property type="term" value="C:tRNA-intron endonuclease complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000213">
        <property type="term" value="F:tRNA-intron lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000379">
        <property type="term" value="P:tRNA-type intron splice site recognition and cleavage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd22363">
        <property type="entry name" value="tRNA-intron_lyase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1350.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011856">
        <property type="entry name" value="tRNA_endonuc-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036167">
        <property type="entry name" value="tRNA_intron_Endo_cat-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006677">
        <property type="entry name" value="tRNA_intron_Endonuc_cat-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006676">
        <property type="entry name" value="tRNA_splic"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00324">
        <property type="entry name" value="endA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21227">
        <property type="entry name" value="TRNA-SPLICING ENDONUCLEASE SUBUNIT SEN2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21227:SF0">
        <property type="entry name" value="TRNA-SPLICING ENDONUCLEASE SUBUNIT SEN2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01974">
        <property type="entry name" value="tRNA_int_endo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53032">
        <property type="entry name" value="tRNA-intron endonuclease catalytic domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0540">Nuclease</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="tRNA intron endonuclease catalytic" evidence="4">
        <location>
            <begin position="70"/>
            <end position="152"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012573"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00034031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OBZ87342.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="182" mass="21624" checksum="256E5B25FC07E580" modified="2016-11-30" version="1">MEKDDQDGTLSSSELLILTDQQDLEKLQLDLFEAFFLTYGLNALSIYDSLQAPLSIETCWTLFCKADPSFHYKYAVYHYYRSLGWVPKNGLKFGVDFVLYQRGPSFRHADYAVVIIPVEMHKEEARMSWQWLLRLNRICNQVKKTLLLCYVDIPETVCHSRLNEYHIRQVTYKRWSPQRNRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NES1</accession>
    <name>A0A1C7NES1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Phosducin-like protein 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">Pdcl3</name>
        <name evidence="4" type="ORF">A0J61_04378</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the phosducin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000213">
        <property type="protein sequence ID" value="OBZ87577.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NES1"/>
    <dbReference type="FunCoup" id="A0A1C7NES1">
        <property type="interactions" value="468"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NES1"/>
    <dbReference type="InParanoid" id="A0A1C7NES1"/>
    <dbReference type="OrthoDB" id="45518at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003779">
        <property type="term" value="F:actin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031683">
        <property type="term" value="F:G-protein beta/gamma-subunit complex binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030036">
        <property type="term" value="P:actin cytoskeleton organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071444">
        <property type="term" value="P:cellular response to pheromone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:1903333">
        <property type="term" value="P:negative regulation of protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051726">
        <property type="term" value="P:regulation of cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd02988">
        <property type="entry name" value="Phd_like_VIAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051498">
        <property type="entry name" value="Phosducin-like_chap/apop_reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024253">
        <property type="entry name" value="Phosducin_thioredoxin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45809">
        <property type="entry name" value="VIRAL IAP-ASSOCIATED FACTOR HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45809:SF3">
        <property type="entry name" value="VIRAL IAP-ASSOCIATED FACTOR HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02114">
        <property type="entry name" value="Phosducin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Phosducin" evidence="3">
        <location>
            <begin position="61"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="203"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="214"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="232"/>
            <end position="244"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009686"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02114"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OBZ87577.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="244" mass="27760" checksum="411463188D9A971B" modified="2016-11-30" version="1">MDDPNADTEWNDILRAKGILPPKDEKKDDELEDAFVEMVQARQAKLDSLENKDLDELDELEDLEDDQILNQYRHKRMMEMQAQAAKEKYGEITEISKPDFVREVTEASKECHVVVHLYKDAIPASRLMHRCLSELALQFKATKFVRIVSDQCIPNYPDFNVPTLLIYGEGDIKANLAGAIQFGGMKMTTRSLRSILAKYGAVPAEKSENDDESNNQPKKSIYQSKNTAALSSDEDSDDDDRGYY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-06-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NFE2</accession>
    <name>A0A1C7NFE2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_04136</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000195">
        <property type="protein sequence ID" value="OBZ87822.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NFE2"/>
    <dbReference type="InParanoid" id="A0A1C7NFE2"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ87822.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="59" mass="6578" checksum="F22CAA18A2D75B8C" modified="2016-11-30" version="1">MSTLEQAKKLFDHSSPPPPLCSSVFTHYVKENTVFSVCIAPNGNHVIVDIHDLHFNEDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NFU3</accession>
    <name>A0A1C7NFU3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">FUN14 domain-containing protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">Fundc1</name>
        <name evidence="6" type="ORF">A0J61_04121</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the FUN14 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000194">
        <property type="protein sequence ID" value="OBZ87840.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NFU3"/>
    <dbReference type="STRING" id="101091.A0A1C7NFU3"/>
    <dbReference type="InParanoid" id="A0A1C7NFU3"/>
    <dbReference type="OrthoDB" id="163794at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007014">
        <property type="entry name" value="FUN14"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21346">
        <property type="entry name" value="FUN14 DOMAIN CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21346:SF10">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04930">
        <property type="entry name" value="FUN14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OBZ87840.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="193" mass="21922" checksum="06DA19AE9BAF12CA" modified="2016-11-30" version="1">MFRLSRTIQTNAFRACQTRTLKPTQARWFTHIKPLQTSKIIPTLAVTTTTLAAPLLFKQPVHCQAAFVEPPVMQESPILKQTDKSVFNRNELTFGTFLGLCTGFLVKKVGKIFAGCVGLGFVFLQYLSHEGYVTVHWDRLQGRYTNSLDLDKDGRVTRGDLNSTWQKFVNFLTNNIQFKSTFLIGFYAGLRYG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NG29</accession>
    <name>A0A1C7NG29_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Apoptosis-inducing factor B</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">aifB</name>
        <name evidence="6" type="ORF">A0J61_04253</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the FAD-dependent oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000204">
        <property type="protein sequence ID" value="OBZ87689.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NG29"/>
    <dbReference type="STRING" id="101091.A0A1C7NG29"/>
    <dbReference type="InParanoid" id="A0A1C7NG29"/>
    <dbReference type="OrthoDB" id="202203at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004174">
        <property type="term" value="F:electron-transferring-flavoprotein dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07440">
        <property type="entry name" value="RGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.167.10">
        <property type="entry name" value="Regulator of G-protein Signalling 4, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023753">
        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016137">
        <property type="entry name" value="RGS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036305">
        <property type="entry name" value="RGS_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044926">
        <property type="entry name" value="RGS_subdomain_2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43735">
        <property type="entry name" value="APOPTOSIS-INDUCING FACTOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43735:SF3">
        <property type="entry name" value="FERROPTOSIS SUPPRESSOR PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00615">
        <property type="entry name" value="RGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00368">
        <property type="entry name" value="FADPNR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00315">
        <property type="entry name" value="RGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48097">
        <property type="entry name" value="Regulator of G-protein signaling, RGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50132">
        <property type="entry name" value="RGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RGS" evidence="5">
        <location>
            <begin position="9"/>
            <end position="118"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006442"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50132"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OBZ87689.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="581" mass="64911" checksum="E2E412531195F72D" modified="2016-11-30" version="1">MESSLIEFELKDVLQDPILLNSFEGFLTTKGEQKNLFFIEAMNQLRHEVDSSKEIEDTLYRIYTSFIKKGSLLQIDITTRQSVESRIQSSRWATLDQEEATDILRETEHEVMAILSRELDVFLSASRHDGSLRRLRVNNGPTNSLQKRVLIVGGGFTGFTVASILDPMPLFHVTLIDTKDSFEYTPQILSKIANPKQSSSLRFPHSSYVKNGKVIIGYAEDICQDAKCVKVNSEEIGFDYLVVAPGSSYAGQFKSTDHSSLYRATGLKKIADDILSAKNILIIGAGLVGCELAATIAQQEHHPKKKVLLVESQDKIIPRSSEKQRKKAMEYLAGLGVEVILNERITFISMDEADTYHGSSGRVYSSRDYTVLMATGVRVNSGFVRNSTNTPSLETCVDNYGLIRVRPTLQIAHWKYNHIFAGGDATNVIEEKTAYAATIAGVCIARNICRLEKGKEPIEQGHKGLLAPPLKTLHGIKSQGGIGKKPLSFLERKLSFLNPTWQILKFFNEQQFFDLVQKTSRKSSLIGRIPRTMQLPKQHTNALHSKLIDSLSDHMSSDTSSCGNSQINSIWSDEMDQDVLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NG74</accession>
    <name>A0A1C7NG74_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Extracellular membrane protein CFEM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_03920</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000180">
        <property type="protein sequence ID" value="OBZ88035.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NG74"/>
    <dbReference type="STRING" id="101091.A0A1C7NG74"/>
    <dbReference type="InParanoid" id="A0A1C7NG74"/>
    <dbReference type="OrthoDB" id="2289000at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008889681" description="Extracellular membrane protein CFEM domain-containing protein" evidence="2">
        <location>
            <begin position="23"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="64"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="67"/>
            <end position="84"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ88035.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="218" mass="21434" checksum="CB1E44F791A01B80" modified="2016-11-30" version="1">MYAKIFAIAIAVFVCFIAQVHAACDCDEGDTSCLRKCVTTGQSCIDDCNGDTSCYNECISNHWPGQSGSSSSRSTTADAATTTSSAAAESTTTVAIATTTVASSSAEPTETASNVLISSVSIVASSVTSAPAPTSSEVQVPSSILSSIASVASSAASSAVADASSAVSSQLAASASSAAAASSSAAASSTPEAQNAGSMVKPTFALVAISFIFAQLMF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NGQ7</accession>
    <name>A0A1C7NGQ7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_03672</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000162">
        <property type="protein sequence ID" value="OBZ88283.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NGQ7"/>
    <dbReference type="InParanoid" id="A0A1C7NGQ7"/>
    <dbReference type="OrthoDB" id="2299857at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="130"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="151"/>
            <end position="162"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ88283.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="176" mass="19888" checksum="F1EE82902094B825" modified="2016-11-30" version="1">MVVSAVASSSSSAFVPVITHDPQQVQAKCFSKPTSMDPNARCYLPTYRPQNDRMIPSFIEIPPQKEMTYHHRYSPSLPSPSSLIWSNSQHEVAKSFSTPEENATSSYFGYTSPSYLTKQLEGQLSPTEKTYADNARSLDKDSKHKLYTPYRNYSQPSQNNMPFTPHAMYSNPSSFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NGU5</accession>
    <name>A0A1C7NGU5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Translation initiation factor eIF2B subunit delta</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">eIF2B GDP-GTP exchange factor subunit delta</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="primary">Eif2b4</name>
        <name evidence="10" type="ORF">A0J61_03741</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="8">Component of the translation initiation factor 2B (eIF2B) complex which is a heterodecamer of two sets of five different subunits: alpha, beta, gamma, delta and epsilon. Subunits alpha, beta and delta comprise a regulatory subcomplex and subunits epsilon and gamma comprise a catalytic subcomplex. Within the complex, the hexameric regulatory complex resides at the center, with the two heterodimeric catalytic subcomplexes bound on opposite sides.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytosol</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the eIF-2B alpha/beta/delta subunits family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000167">
        <property type="protein sequence ID" value="OBZ88210.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NGU5"/>
    <dbReference type="STRING" id="101091.A0A1C7NGU5"/>
    <dbReference type="InParanoid" id="A0A1C7NGU5"/>
    <dbReference type="OrthoDB" id="10254737at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10470">
        <property type="entry name" value="Translation initiation factor eif-2b, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000649">
        <property type="entry name" value="IF-2B-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042529">
        <property type="entry name" value="IF_2B-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037171">
        <property type="entry name" value="NagB/RpiA_transferase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10233">
        <property type="entry name" value="TRANSLATION INITIATION FACTOR EIF-2B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10233:SF14">
        <property type="entry name" value="TRANSLATION INITIATION FACTOR EIF-2B SUBUNIT DELTA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01008">
        <property type="entry name" value="IF-2B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100950">
        <property type="entry name" value="NagB/RpiA/CoA transferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 10" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="5" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="10">
        <location>
            <position position="216"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004514"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00044147"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00044356"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00046432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU003814"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OBZ88210.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="216" mass="23955" checksum="8F2743300990FE96" modified="2016-11-30" version="1" fragment="single">MADQLIVQNGLQKIQDGDVILTFAKSSVVESLLLETKKKGIDFKVIVVDSRPLFEGKHLLRRLVAAGIDCSYHLLSSVYVALKSVTKVIMGAHALLNNGAVYSRIGSSMVAMAASDKQIPVMICCETYKFVNRTQVDSFVLNELGNPDDLVNTHKNETAALVNWRDQPDLRLLNLLYDVTPSKYITLVVTEVGLIPCTSAPVIWREYNEEFGKRVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NH05</accession>
    <name>A0A1C7NH05_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Mitochondrial chaperone BCS1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">BCS1_0</name>
        <name evidence="6" type="ORF">A0J61_03535</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the AAA ATPase family. BCS1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000154">
        <property type="protein sequence ID" value="OBZ88403.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NH05"/>
    <dbReference type="InParanoid" id="A0A1C7NH05"/>
    <dbReference type="OrthoDB" id="10251412at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014851">
        <property type="entry name" value="BCS1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050747">
        <property type="entry name" value="Mitochondrial_chaperone_BCS1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23070">
        <property type="entry name" value="BCS1 AAA-TYPE ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08740">
        <property type="entry name" value="BCS1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="3" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="5">
        <location>
            <begin position="280"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="502"/>
            <end position="646"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="519"/>
            <end position="534"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="535"/>
            <end position="567"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="585"/>
            <end position="616"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="623"/>
            <end position="639"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OBZ88403.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="646" mass="74641" checksum="BEAEF631AD5474EB" modified="2016-11-30" version="1">MSEVAKPFHRITGAVNLVLTVLEKISDETIWKQIFGERIVNLLQKYFGNDFVALSLAIYIAPILKNYWSNVSKRYMVKMVPMGRVSLRVCSSDSLYQCISKYAADHGTTRRNLRSGVVQHAEPYNRITXSVDDYDRSESDEQVVKKVENEEEELAKVRLLPPDEYTEFVFYKGNYITLEFKDSGYVENEWIWEHVLVSMSGRSIKELHIILQEWSDDYNKNLSCRQIFRSSGASWQYERDLPKRDLDSIHLCHGQKELMIRDMQTFRTRGDWYKKRGIPYRRGYLLYGPPGTGKTSTIQAIANHLDLHISIVNCVTELSQDDLSSLIQSVPYHSIVVIEDIDHLFDSKKKKDDEESENNAITMSGLLNIMDGMHGQEGSMIFMTCNNINKIQPALLRPGRVDMKIKLDYAAIEQVKGTFWRFMGLDDETSLPLEGADKEEAEVHLKTFAAKIPVDHVTTAELQSFFIDLLLEAKHMGWNRNETYDVMFKRIPDFLERVKRDREQAKKHEGIEDDEDKKEEENKEVKEEEKKEEEAKEDEVKEEEAKEEEAKEDEVKEEEAKEEENNEESVKTEDTKEEDTTTEAVKAKEEDTKTEEVSHSTDETDKHSDSSDDTDHSSGAFDDTDRGSETSEDEREFKDCPASSTN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NH75</accession>
    <name>A0A1C7NH75_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 7">ER membrane protein complex subunit 3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">A0J61_05245</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">The EMC seems to be required for efficient folding of proteins in the endoplasmic reticulum (ER).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the EMC3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000278">
        <property type="protein sequence ID" value="OBZ86714.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NH75"/>
    <dbReference type="FunCoup" id="A0A1C7NH75">
        <property type="interactions" value="255"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NH75"/>
    <dbReference type="InParanoid" id="A0A1C7NH75"/>
    <dbReference type="OrthoDB" id="6745403at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072546">
        <property type="term" value="C:EMC complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032977">
        <property type="term" value="F:membrane insertase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051087">
        <property type="term" value="F:protein-folding chaperone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006644">
        <property type="term" value="P:phospholipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015914">
        <property type="term" value="P:phospholipid transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034975">
        <property type="term" value="P:protein folding in endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045050">
        <property type="term" value="P:protein insertion into ER membrane by stop-transfer membrane-anchor sequence"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008568">
        <property type="entry name" value="EMC3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002809">
        <property type="entry name" value="EMC3/TMCO1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13116">
        <property type="entry name" value="ER MEMBRANE PROTEIN COMPLEX SUBUNIT 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13116:SF5">
        <property type="entry name" value="ER MEMBRANE PROTEIN COMPLEX SUBUNIT 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01956">
        <property type="entry name" value="EMC3_TMCO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF010045">
        <property type="entry name" value="DUF850_TM_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01415">
        <property type="entry name" value="DUF106"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="16"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="132"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="179"/>
            <end position="197"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005376"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00020822"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRNR" id="PIRNR010045"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OBZ86714.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="291" mass="33018" checksum="8C882F636A3A5CD5" modified="2016-11-30" version="1">MSDVQRMILDPAIRDWVLIPIMIVMVLVGILRHYITMLITGTPKRPQLKAIRESKALLSGLRLRSIGNYVPQHAFNVRKAYLADAFEKGKYLKNPNATKETAGPVNPMTDPDMMEGMMEGMKKQLMNMVPQMVIMGWINFFFQGFVVIKLPFPLTPRFKQMLQSGVDTRDMDVTWVSSLSWYFLNLFGLGSVFSLILGGENAAGVDMTAMSTMPGMMPGQGQPGQPQDFNKLFLAEKENIMITPHEWDLEDIEERLLKKYGKPVVPKKVVEEPKKPISVREKIKAAQNKRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NHT2</accession>
    <name>A0A1C7NHT2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Rho GTPase-activating protein 39</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">ARHGAP39_0</name>
        <name evidence="5" type="ORF">A0J61_03277</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000138">
        <property type="protein sequence ID" value="OBZ88671.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NHT2"/>
    <dbReference type="STRING" id="101091.A0A1C7NHT2"/>
    <dbReference type="InParanoid" id="A0A1C7NHT2"/>
    <dbReference type="OrthoDB" id="437889at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005856">
        <property type="term" value="C:cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.555.10:FF:000045">
        <property type="entry name" value="RhoGAP domain containing protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.70.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.530">
        <property type="entry name" value="MyTH4 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.555.10">
        <property type="entry name" value="Rho GTPase activation protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000857">
        <property type="entry name" value="MyTH4_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038185">
        <property type="entry name" value="MyTH4_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008936">
        <property type="entry name" value="Rho_GTPase_activation_prot"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000198">
        <property type="entry name" value="RhoGAP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001202">
        <property type="entry name" value="WW_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45876">
        <property type="entry name" value="FI04035P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45876:SF8">
        <property type="entry name" value="FI04035P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00784">
        <property type="entry name" value="MyTH4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00620">
        <property type="entry name" value="RhoGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00139">
        <property type="entry name" value="MyTH4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00324">
        <property type="entry name" value="RhoGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00456">
        <property type="entry name" value="WW"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48350">
        <property type="entry name" value="GTPase activation domain, GAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51016">
        <property type="entry name" value="MYTH4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50238">
        <property type="entry name" value="RHOGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50020">
        <property type="entry name" value="WW_DOMAIN_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="WW" evidence="2">
        <location>
            <begin position="2"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="domain" description="WW" evidence="2">
        <location>
            <begin position="44"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="domain" description="MyTH4" evidence="4">
        <location>
            <begin position="318"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="domain" description="Rho-GAP" evidence="3">
        <location>
            <begin position="487"/>
            <end position="670"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="111"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50238"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OBZ88671.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="691" mass="78740" checksum="17C05677F251E077" modified="2016-11-30" version="1">MSTTEYDWVEIANPKLTTPFYANLATGECSWTKPAEDSMIKENDPQGDWWELWDEKNKLPYYYHTRANVSNWSKPTDAHIISLINMKPSDEFAQQLSSIIQQPLDMTMKRNSKSLDLPNNNNKHLESKQHHHHNRSTSDSGKHIEQVIFDLPPQSTDTNSLSSALNDTSPRLFQFSRKHSYCSIQKELAPNDTKTSRRASHFSAFSSFTKSSNPLRSLVSRSSSPTSESRYSTMTISAPLNNPEAAAGMHPLSQIDFEKAGSKQSLSMFGSMRKPALPAGLQQEITRFAIDGFAKKYFATHKRGLFRRRVPMNQMLKWTKESIKQPLIMMNKDFNKDALKCFKLLQMIMGDRPRPRNTSEIEDIQFILTCGITKGQMRDEIYVQICKQLQDNPHNDSIRKGWEMLCIVSITFPPSKNLESYLTDFVQQHHSVQENDVCIMSQHVSAKLRRICTRGAKGKVLTSAEINRAKEAPFKPSVFGESLDFIMELQEKTHPELFIPQIVTFLTKTVRDTNGQMSEGIFRVPGDADAVTDLRVRIENGQYDASNVTDPNVPASLFKYWLRDLAEPIVSPEDYDDCIRHAENPAKAIAIINRLPDVNRRIALFTISFLQEFTQPEIIKHTLMNVNNLAMVFAPNFLRCPSESLTTVFENSKYEQAFLRTLIDKMVIDPNACAYDPDTTKAIGHYNEPSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NI58</accession>
    <name>A0A1C7NI58_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="10">DNA repair protein rhp42</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">rhp42</name>
        <name evidence="10" type="ORF">A0J61_03259</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the XPC family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000137">
        <property type="protein sequence ID" value="OBZ88698.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NI58"/>
    <dbReference type="FunCoup" id="A0A1C7NI58">
        <property type="interactions" value="96"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NI58"/>
    <dbReference type="InParanoid" id="A0A1C7NI58"/>
    <dbReference type="OrthoDB" id="300780at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000111">
        <property type="term" value="C:nucleotide-excision repair factor 2 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071942">
        <property type="term" value="C:XPC complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003684">
        <property type="term" value="F:damaged DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006298">
        <property type="term" value="P:mismatch repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006289">
        <property type="term" value="P:nucleotide-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.2460:FF:000001">
        <property type="entry name" value="DNA repair protein Rad4 family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.20.110">
        <property type="entry name" value="Rad4, beta-hairpin domain BHD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.2460">
        <property type="entry name" value="Rad4, beta-hairpin domain BHD3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.260.10">
        <property type="entry name" value="Transglutaminase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018327">
        <property type="entry name" value="BHD_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004583">
        <property type="entry name" value="DNA_repair_Rad4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018325">
        <property type="entry name" value="Rad4/PNGase_transGLS-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018326">
        <property type="entry name" value="Rad4_beta-hairpin_dom1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018328">
        <property type="entry name" value="Rad4_beta-hairpin_dom3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042488">
        <property type="entry name" value="Rad4_BHD3_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036985">
        <property type="entry name" value="Transglutaminase-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12135:SF0">
        <property type="entry name" value="DNA REPAIR PROTEIN COMPLEMENTING XP-C CELLS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12135">
        <property type="entry name" value="DNA REPAIR PROTEIN XP-C / RAD4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10403">
        <property type="entry name" value="BHD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10404">
        <property type="entry name" value="BHD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10405">
        <property type="entry name" value="BHD_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03835">
        <property type="entry name" value="Rad4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01030">
        <property type="entry name" value="BHD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01031">
        <property type="entry name" value="BHD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01032">
        <property type="entry name" value="BHD_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0227">DNA damage</keyword>
    <keyword evidence="4" id="KW-0234">DNA repair</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rad4 beta-hairpin" evidence="7">
        <location>
            <begin position="452"/>
            <end position="503"/>
        </location>
    </feature>
    <feature type="domain" description="Rad4 beta-hairpin" evidence="8">
        <location>
            <begin position="505"/>
            <end position="567"/>
        </location>
    </feature>
    <feature type="domain" description="Rad4 beta-hairpin" evidence="9">
        <location>
            <begin position="574"/>
            <end position="648"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="41"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="66"/>
            <end position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM01030"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM01031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM01032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OBZ88698.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="721" mass="83232" checksum="FCECA0D15CA1636E" modified="2016-11-30" version="1">MVSTRSGSSTKGKQTPLKRRNTEKNTPRKKSKGKQTIAHVDSTDEEHQPEEFIKVDLPVQNPFAEQENEEDESEEEDEIDWETVSLPPRFNEMGSFEQHLPEENVYKDVEIVMEAPRPVLKESNWEKAYQRNLREWMHHSHVVLLTAHYKWRNYWCSHAEMKSVCRSVIPDHAKRLLSKDKTEATLKTGIKWLIGWWTDYFRLTGPGLLTVPYHEAFRSDITLRQWIDQKQSDESNDYIENLEAWMNLLSVRSGTRDTSAELFVALLRACGCDARLVCSIQPLPYKIPPASKKIQQETPVEEEEEKTGQAMFPFRPRSKAYVSPDKELKSPKAKPPCVWAEVWCEDTQRWICVDMIRNYIDRPGLMEPAALNRSNTMSFVLAFSADNRNVIDVARRYTSNLEKAVRLREPPLTKREKEGGMKLWSDIFLSTLVQQHDERDVIEKASLDELETREMMPTSINGFKNHPVYALERHLKKFEILHPREPVLGSIRGEKVYPRSCVKTVSTADAYRKMGKEIKPGEQPVKMVKANAVTIEKRRLKEQAKQDSQELLVPCYGEWQTQYYRPPPLIHGKLVKNAYGTIDLFTSSMLPQGAAHIPIKGIAKIAKKLNIDYAEAVVDFEFMKMRAVPITNGIVVAEEHEPILLEAWEDYEQNEANKAIAKQEKEVYKRWRKLIKGLLIKAHVDKSYGKTDEDELKKKWDAFNHSASPAIDGGGFLPEED</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NIC9</accession>
    <name>A0A1C7NIC9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">B(0,+)-type amino acid transporter 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">SLC7A9</name>
        <name evidence="7" type="ORF">A0J61_03088</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000127">
        <property type="protein sequence ID" value="OBZ88862.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NIC9"/>
    <dbReference type="STRING" id="101091.A0A1C7NIC9"/>
    <dbReference type="InParanoid" id="A0A1C7NIC9"/>
    <dbReference type="OrthoDB" id="10062876at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015179">
        <property type="term" value="F:L-amino acid transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1740.10">
        <property type="entry name" value="Amino acid/polyamine transporter I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002293">
        <property type="entry name" value="AA/rel_permease1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050598">
        <property type="entry name" value="AminoAcid_Transporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11785">
        <property type="entry name" value="AMINO ACID TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11785:SF512">
        <property type="entry name" value="SOBREMESA, ISOFORM B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13520">
        <property type="entry name" value="AA_permease_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006060">
        <property type="entry name" value="AA_transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="53"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="85"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="127"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="180"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="210"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="249"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="286"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="327"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="386"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="414"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="445"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="472"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OBZ88862.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="548" mass="59456" checksum="7D1A3DCA2A0FCD15" modified="2016-11-30" version="1">MKSFLSALNGTKSSSNGDQLEKTNSITSIESGAMTPSHHSENEGGTPTVAPHMGLISSCNMIVGLIIGSGIFASPGPVTLKVHAVGPSLIVWAIGGFLSMIGALCYAELGTMITKSGGEYQYLKSAFGLCFGLTFTWSNLLLANPIGTASIATVFAQYIMQMAYYDPSDPSGKNIVMQDYAVKLVAIACIWVVVLFNAFGRKAGAMIQNVFTGAKLLALVMIIIIGWVWLGKGNTANFQNAFNNSSTNALDYGTAMYMALFSYNGWNNLNYGISEVKNPKRNVPLAISISCFLVTMVYVLSNIAYFATLPVETVATSSTVAMQVGSVSMGTGGAYFFALMVVLSTFGAVNGNVWAASRLVLTSATEDTVFMPPLFGKMAKKQQTPIAALVLVGIIATIWCIPGDFTYLAKMYSFIYWLFYGFTVAALIVMRFKKSTRDLPRPFKIWLPFAIFFLIIDIYLIVAPLVDAGSDGVYQYIICIVIGLLAIPIWFVRVKRPSIGRTLFGWIPGYQDALILESRRKKAEKNARMTSETVLNEPVPVGLEKTEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NIF2</accession>
    <name>A0A1C7NIF2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Transcription activator GCR1-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_03160</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000131">
        <property type="protein sequence ID" value="OBZ88798.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NIF2"/>
    <dbReference type="InParanoid" id="A0A1C7NIF2"/>
    <dbReference type="OrthoDB" id="428577at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0060963">
        <property type="term" value="P:positive regulation of ribosomal protein gene transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052146">
        <property type="entry name" value="HOT1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022210">
        <property type="entry name" value="TF_GCR1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37784:SF2">
        <property type="entry name" value="HIGH-OSMOLARITY-INDUCED TRANSCRIPTION PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37784">
        <property type="entry name" value="PROTEIN MSN1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12550">
        <property type="entry name" value="GCR1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Transcription activator GCR1-like" evidence="2">
        <location>
            <begin position="268"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="135"/>
            <end position="162"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12550"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ88798.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="365" mass="42263" checksum="A23B96CDC70A49AE" modified="2016-11-30" version="1">MKLRRSNRNAPRAIEERNSITDRVAYSQQKDFKEWCRAKNFDDGDLIYEEKLRDFLIDYVFRRKKRIITAMSKDQPYLGEDAIGRYVFSIVQLHKQQIAQNINSYDNPNGPLVKEAIQEHLDKNPNLRKGLRLRYQEKGKKASSSTTLSRNDRHRRHSLNRNEPCIKQFMKLKSEMEAGINILSSLIQAEEDGHQLHIEKIRQTLMNMLDSSNIRSRSSAEAAAAASLISPTPSLENLTNASSLSLHDSVDLPDICTKKSPPKQSPDRSIRSVSDAWREYSIGTNGGLPLKYLEENFGMSWLKRDTPMNDYCFYERRKHLINLIKRIAKNENVSQEEVAERLEMERKARKVRLDKLSTILIDEGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-06-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NIJ9</accession>
    <name>A0A1C7NIJ9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_03135</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000130">
        <property type="protein sequence ID" value="OBZ88810.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NIJ9"/>
    <dbReference type="InParanoid" id="A0A1C7NIJ9"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ88810.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="64" mass="7483" checksum="554DE8EF527B0E95" modified="2016-11-30" version="1">MEKSNILTLEIKTKLDFISPQLEDKSKRYGCFDGGTKLGQLNTKRIYRTYSKQKVLSVRFDYTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NIZ4</accession>
    <name>A0A1C7NIZ4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">YCII-related domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_02978</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000121">
        <property type="protein sequence ID" value="OBZ88970.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NIZ4"/>
    <dbReference type="STRING" id="101091.A0A1C7NIZ4"/>
    <dbReference type="InParanoid" id="A0A1C7NIZ4"/>
    <dbReference type="OrthoDB" id="5519740at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1060">
        <property type="entry name" value="Dimeric alpha+beta barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011008">
        <property type="entry name" value="Dimeric_a/b-barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051807">
        <property type="entry name" value="Sec-metab_biosynth-assoc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005545">
        <property type="entry name" value="YCII"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33606">
        <property type="entry name" value="PROTEIN YCII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33606:SF3">
        <property type="entry name" value="PROTEIN YCII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03795">
        <property type="entry name" value="YCII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54909">
        <property type="entry name" value="Dimeric alpha+beta barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="YCII-related" evidence="1">
        <location>
            <begin position="31"/>
            <end position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03795"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ88970.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="126" mass="14164" checksum="9A3ACB4FF7B48BFF" modified="2016-11-30" version="1">MLNKLISCSGFRQVTRRCFTTNGLVLDKKQFVVVVKDYEDSECLQRRLEIREKHLSKAHDAKDNGTLLAGGAILDDHASGKMKGSVLLVSAGSPEEVETMIKSDPYYKAKVWESWRIHPIKLAIGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NK16</accession>
    <name>A0A1C7NK16_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Serine/threonine-protein phosphatase</fullName>
            <ecNumber evidence="7">3.1.3.16</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">pphA_1</name>
        <name evidence="10" type="ORF">A0J61_02477</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:47004"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="EC" id="3.1.3.16"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the PPP phosphatase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.16" evidence="7"/>
    <dbReference type="EMBL" id="LUGH01000094">
        <property type="protein sequence ID" value="OBZ89467.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NK16"/>
    <dbReference type="FunCoup" id="A0A1C7NK16">
        <property type="interactions" value="433"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NK16"/>
    <dbReference type="InParanoid" id="A0A1C7NK16"/>
    <dbReference type="OrthoDB" id="1930084at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004722">
        <property type="term" value="F:protein serine/threonine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd07415">
        <property type="entry name" value="MPP_PP2A_PP4_PP6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.21.10:FF:000003">
        <property type="entry name" value="Serine/threonine-protein phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047129">
        <property type="entry name" value="PPA2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006186">
        <property type="entry name" value="Ser/Thr-sp_prot-phosphatase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45619">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN PHOSPHATASE PP2A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00114">
        <property type="entry name" value="STPHPHTASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00156">
        <property type="entry name" value="PP2Ac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="Metallo-dependent phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00125">
        <property type="entry name" value="SER_THR_PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0464">Manganese</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0904">Protein phosphatase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Serine/threonine specific protein phosphatases" evidence="9">
        <location>
            <begin position="114"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="342"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="342"/>
            <end position="378"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00048336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU004273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS00125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OBZ89467.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="384" mass="43993" checksum="C94DC5489B1AAB80" modified="2016-11-30" version="1">MTAVSSVADVDAWIAQLSECKQLPESEIRKLCDKAREILKEESNVQPVKCPVTVCGDIHGQFHDLQELFRIGGNSPDTNYLFMGDYVDRGYYSVETVTFLVALKVRYKDRITILRGNHESRQITQVYGFYDECLRKYGNANVWKMFTDLFDYLPLTALIEDQIFCLHGGLSPSIDTLDQVRGLDRIQEVPHEGPMCDLLWSDPDDRCGWGISPRGAGYTFGQDIAETFNHNNGLTLVARAHQLVMEGYNWTHDRNVVTIFSAPNYCYRCGNQAAIMEIDEHMKYTFLQFDPAPRKGEPHVTRRTPDYFLSCYLFRKNPGFDEIKVHNSDSLMENAPEWKEATATESEADIKAEKEPEVSPQVLREETAEWVRSHRDSEGNIPMH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NKU0</accession>
    <name>A0A1C7NKU0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Pentatricopeptide repeat-containing protein 5, mitochondrial</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">ppr5_2</name>
        <name evidence="7" type="ORF">A0J61_02346</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Regulates mitochondrial small subunit maturation by controlling 15S rRNA 5'-end processing. Localizes to the 5' precursor of the 15S rRNA in a position that is subsequently occupied by mS47 in the mature yeast mtSSU. Uses structure and sequence-specific RNA recognition, binding to a single-stranded region of the precursor and specifically recognizing bases -6 to -1. The exchange of Ccm1 for mS47 is coupled to the irreversible removal of precursor rRNA that is accompanied by conformational changes of the mitoribosomal proteins uS5m and mS26. These conformational changes signal completion of 5'-end rRNA processing through protection of the mature 5'-end of the 15S rRNA and stabilization of mS47. The removal of the 5' precursor together with the dissociation of Ccm1 may be catalyzed by the 5'-3' exoribonuclease Pet127. Involved in the specific removal of group I introns in mitochondrial encoded transcripts.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Binds to mitochondrial small subunit 15S rRNA.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the CCM1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000087">
        <property type="protein sequence ID" value="OBZ89608.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NKU0"/>
    <dbReference type="FunCoup" id="A0A1C7NKU0">
        <property type="interactions" value="184"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NKU0"/>
    <dbReference type="InParanoid" id="A0A1C7NKU0"/>
    <dbReference type="OrthoDB" id="411857at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002885">
        <property type="entry name" value="PPR_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00756">
        <property type="entry name" value="PPR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47447">
        <property type="entry name" value="OS03G0856100 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47447:SF17">
        <property type="entry name" value="OS12G0638900 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01535">
        <property type="entry name" value="PPR"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13041">
        <property type="entry name" value="PPR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13812">
        <property type="entry name" value="PPR_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51375">
        <property type="entry name" value="PPR"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="PPR" evidence="5">
        <location>
            <begin position="384"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="repeat" description="PPR" evidence="5">
        <location>
            <begin position="834"/>
            <end position="868"/>
        </location>
    </feature>
    <feature type="repeat" description="PPR" evidence="5">
        <location>
            <begin position="979"/>
            <end position="1014"/>
        </location>
    </feature>
    <feature type="repeat" description="PPR" evidence="5">
        <location>
            <begin position="1094"/>
            <end position="1128"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="26"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="39"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="58"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00044493"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00044511"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00708"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OBZ89608.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="1138" mass="129570" checksum="B6EC2D8810BA3F3D" modified="2016-11-30" version="1">MLEKLSSSGSHLKIHTLDSNKQMCNQHKKPTKHNRTRNRPLSPSKQTRSPSEDTQNDLLTPPNSPTSSSSQLPSSSSRHYHKKKNNQTYECNHRILTAKRNGDLRTVMNEFISMKKNKIQMTHHTYNLVLEAHILLRREGTPLTQMLKLYQEMAHYQIRPNTYTYVLMIRSLCKRDVEVQKTVAMLKRQSARIGHNNEDVGLLESEGNLTMALAIFHHAVANDMAICSFEIEIFNQLLRVLSHYGNTADAHFVYAQLERPEVQAKPNSATYAALINLFGRAGDIQTALYYYDVYSHVKNTLGAHDASYIFNALVDCHLKCGMLDAALHVVEHDMAQHHIKLTCIPYNSIIRHYCTHDQMKEAEDLIKRLLKGHQENGKRYPLPDASSYGPILSAYCQNDQWPEATRIYDALRETDISKAYGNLANYALLCLSHDDLDKALMVIHDMTKASLEPDPVLAERIVSRFAQSNYIEEAIQALELMEQVMSVRSLVKGAHCLLDAALEIVLHCTTVHQVLQVMHCVMSILRHSAAHPSSSESSSFGIMCKTLIDSYFDQPLEMHSAFSHADYRLLFESCFVVYSKHELPSLETAMMQILQDMHGLRIAVDSNLIEFVATRLQLYNQTEAEARWRAAVVQSSLKEQPEEINLQEEKERDDGDVIIEIVDDEESSLDGLAGVESTCLSEAEAASQAIFQAVQQGHGREAIQIFENRIICRSLIPLPHLMRDAIALAGKQGDLSTALTIYNNAIYAFKDMDDIQLRDEAIYWVTNSLLIGYAQRGEMTQARMYYDRIKAMGYSPDSDGYASLLLGSAQCATDEATDALTIYDEAKRHHVKPTTFFYNVVISKLAKARKLDCALALFEEMRQFHVPANSITYGAIISASVRSGSEHQSCRLFQEMLASPSYQPRVGPFNNMMQFYVRQHPNRERVLDYFNELRRRHIRPSPHSYKLLMEAYTHIAPYDMPMAHKLLGDMTRCDRLHPQATHYATLIYSYGLLQRDVQSAERVFQEMKRVKIHPDEAVYQAMIDTLISNNALEKAEKIYHEEMSQDKQLQKSRSPYIENLFIRGYGQSGQLEKAKVVFEAMSDDKTQQSVVIREPSSYEAMIQAYLLNDQTEPARAILDQMGQRDFPPKVIGVVADLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NKZ7</accession>
    <name>A0A1C7NKZ7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_02293</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000084">
        <property type="protein sequence ID" value="OBZ89660.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NKZ7"/>
    <dbReference type="InParanoid" id="A0A1C7NKZ7"/>
    <dbReference type="OrthoDB" id="2222642at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="6"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="73"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="526"/>
            <end position="548"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="622"/>
            <end position="650"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="629"/>
            <end position="644"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ89660.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="650" mass="72345" checksum="0C589BCC57C5828E" modified="2016-11-30" version="1">MLVSEAVATAIFTITRLLYASALSIVTTIIFSKLPGGSSTKFWYEQPDLVAKITSFFHPFGPTGKRGVKSTNAVAVGCLFLMLALNVLPTILSRLSPITAIDIPGDTNSTLSPISNVFIPTLTDVNLPQLSVPSRSRDATIKFLCSHIEGGCTDARNNTIAKIIWDAVDIRPLRLFHNDSSTNLSVSLDDSFATATTPPQSLQLAKDSLGGQFDYTTSLSFRQWNSNNLTGFYSNAYSSNLANNTFSKYDILNSDQLTPLDTPDLSEMLKQGRRKGEPLPTGGDINRAERWSAIHRTSTLSSVLWQSANAHSGQVGSDWATDCFFCQLIGIQRHSVEANIIYESLTSTNNTDPNRNTFAIQSYVDQESRLSTVLCTVEFNRTSLGLSYWCLHTYSQLWNVYHTGNPYDFLGSYDASASGAEQFSDQSSTPFPFFPPPTNITNKRTYVPIVPIFEIRSRGRCNTDWDFHNQTIQSWMKECAHENLGQLDSTNLTEIARNVWQLSSTITVGGFLVTAQYFTNSMGIDISLPAIVIIGAGLVFCIFGNLIINFVTSPVHRRSLYESIRVMTPDSKDPYNTQRFLLGLSPTNTLRVVESSFDKRISYLKLNNRLIVTLSEKEMSQSDMSINNPEKDNLSTKEPQDWSRRHLINL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NLF4</accession>
    <name>A0A1C7NLF4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Protein fmp32, mitochondrial</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">fmp32</name>
        <name evidence="12" type="ORF">A0J61_02047</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the CCDC90 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000073">
        <property type="protein sequence ID" value="OBZ89895.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NLF4"/>
    <dbReference type="FunCoup" id="A0A1C7NLF4">
        <property type="interactions" value="287"/>
    </dbReference>
    <dbReference type="InParanoid" id="A0A1C7NLF4"/>
    <dbReference type="OrthoDB" id="889336at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033617">
        <property type="term" value="P:mitochondrial respiratory chain complex IV assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.5.340:FF:000018">
        <property type="entry name" value="Mitochondrial protein FMP32"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.340">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024461">
        <property type="entry name" value="CCDC90-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14360">
        <property type="entry name" value="PROTEIN FMP32, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14360:SF1">
        <property type="entry name" value="PROTEIN FMP32, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07798">
        <property type="entry name" value="CCDC90-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="9 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="4 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="175"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="10">
        <location>
            <begin position="96"/>
            <end position="127"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="OBZ89895.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="198" mass="23397" checksum="D1F5ED6E4DCCDED9" modified="2016-11-30" version="1">MASRLLKRNFSYTRRCLADKYHFDTFKFVERLERENFTRQQSEAIMSSLRKVMNESLTELTKPMVTKAEQEKAVYMYKVDFAQLKSEIQFIEKNDFSIMKAENERLQAQVERLRQKLKEEVTRTQANVRLELNLEKGRVKDEASAHEIKMKETDTHIESEIAGLRTQMEAIKFQILQYMVGTMTGAGALFLAYLRMFR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NLT4</accession>
    <name>A0A1C7NLT4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Invertebrate defensins family profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_01907</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000066">
        <property type="protein sequence ID" value="OBZ90057.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NLT4"/>
    <dbReference type="InParanoid" id="A0A1C7NLT4"/>
    <dbReference type="OrthoDB" id="2271042at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008889778" description="Invertebrate defensins family profile domain-containing protein" evidence="1">
        <location>
            <begin position="21"/>
            <end position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ90057.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="73" mass="7933" checksum="9BBFE1F0D50F27EE" modified="2016-11-30" version="1">MKFALYLTIFVAALVMMASAAPSNKRCKTITDAHENAVCKKYCGNSGYLLGECGSSGICLCKNKKYTTKKSKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NM72</accession>
    <name>A0A1C7NM72_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">CTD small phosphatase-like protein 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">CTDSPL2</name>
        <name evidence="4" type="ORF">A0J61_01746</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000059">
        <property type="protein sequence ID" value="OBZ90197.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NM72"/>
    <dbReference type="STRING" id="101091.A0A1C7NM72"/>
    <dbReference type="InParanoid" id="A0A1C7NM72"/>
    <dbReference type="OrthoDB" id="277011at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd07521">
        <property type="entry name" value="HAD_FCP1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd23814">
        <property type="entry name" value="UEV_AKTIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.110.10">
        <property type="entry name" value="Ubiquitin Conjugating Enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004274">
        <property type="entry name" value="FCP1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050365">
        <property type="entry name" value="TIM50"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000608">
        <property type="entry name" value="UBC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016135">
        <property type="entry name" value="UBQ-conjugating_enzyme/RWD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12210">
        <property type="entry name" value="DULLARD PROTEIN PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03031">
        <property type="entry name" value="NIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00179">
        <property type="entry name" value="UQ_con"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00577">
        <property type="entry name" value="CPDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00212">
        <property type="entry name" value="UBCc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54495">
        <property type="entry name" value="UBC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50969">
        <property type="entry name" value="FCP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50127">
        <property type="entry name" value="UBC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FCP1 homology" evidence="3">
        <location>
            <begin position="102"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="domain" description="UBC core" evidence="2">
        <location>
            <begin position="359"/>
            <end position="512"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="661"/>
            <end position="805"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="678"/>
            <end position="695"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="738"/>
            <end position="758"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="759"/>
            <end position="768"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="774"/>
            <end position="794"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50969"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OBZ90197.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="805" mass="91116" checksum="821C24E0B0F2429F" modified="2016-11-30" version="1">MVLTQYQQANVNLPQSYTPTQTQKNQQKALLDQPEAVLASDPPLLTISHSQQTPDDNTLLRVGSLLDQLDDYECSTLDALMARWPSIHTRLKGMKPHLPPKKDDNKPTLVLDLDETLLHTYRNSDNDGLVDYAIYAKDGYSCLLAGRLRPGVIEFLTWAADLFEVVVWTAGCRDYATMARGCLDPDSILISHMLTRESCIRMRSGSTKEVLYIKDLCALGRDLSKTFLVDNTPHAASLNLSNLIPIEAYVGSIFDTELLELRRFLESSLVRLTDKRNDLRIILHRQLNLKRRIRERIGARKMGGSTTRSPNVSNVFSHVRTRSNSVAAAPMHRLRRLSSLDDWDDDNLTPSPHLELSSFKRYELMTEFINLKNSNHCPLGIYMMPSSENLNVWYGVLFVHQGIYQSGVFKFRVAIPESYPEYSPSVTFMSDMFHPLIDGGGNLSMSQQFPTWRPYEDYIFHVLHYIKNIFKKAVLDRLVDRHCLNKEAYRLYRTDKQVFAKLAQQCAQLSVTESYLYDHFPDDNMIRFSPISESRLDSIRSQLIGCDPMLHRLGEEEEEEEEEKEEEVIPTYHGNVENGHIPLIAPTDTLDNTNTEMASNDTLNSANVDIASTETPGNTIVNTTPAETLSNANVDIVSTEAQTAHDLDMSTYDIQAQSPVAESTGADLNKQPMETDRLSQSSNQLEPESPASTQHQHSETDEQPNSDAMNEPDHHKLDQTEDDVDSSNKDSLQQEVEVIDKLPDEETNKDSQKEDRLDSTQAIVQPTEAQLIDEDIKKQAAESVKENSELEVKEVAIMPNKNTHS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NN48</accession>
    <name>A0A1C7NN48_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">[histone H3]-trimethyl-L-lysine(4) demethylase</fullName>
            <ecNumber evidence="4">1.14.11.67</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="19" type="primary">kdm5bb</name>
        <name evidence="19" type="ORF">A0J61_01418</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="19 20" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19 20">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>N(6),N(6),N(6)-trimethyl-L-lysyl(4)-[histone H3] + 3 2-oxoglutarate + 3 O2 = L-lysyl(4)-[histone H3] + 3 formaldehyde + 3 succinate + 3 CO2</text>
            <dbReference type="Rhea" id="RHEA:60208"/>
            <dbReference type="Rhea" id="RHEA-COMP:15537"/>
            <dbReference type="Rhea" id="RHEA-COMP:15547"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:16842"/>
            <dbReference type="ChEBI" id="CHEBI:29969"/>
            <dbReference type="ChEBI" id="CHEBI:30031"/>
            <dbReference type="ChEBI" id="CHEBI:61961"/>
            <dbReference type="EC" id="1.14.11.67"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the JARID1 histone demethylase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="19">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.14.11.67" evidence="4"/>
    <dbReference type="EMBL" id="LUGH01000045">
        <property type="protein sequence ID" value="OBZ90517.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="FunCoup" id="A0A1C7NN48">
        <property type="interactions" value="557"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NN48"/>
    <dbReference type="InParanoid" id="A0A1C7NN48"/>
    <dbReference type="OrthoDB" id="1678912at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000785">
        <property type="term" value="C:chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034647">
        <property type="term" value="F:histone H3K4me/H3K4me2/H3K4me3 demethylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd16100">
        <property type="entry name" value="ARID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd15545">
        <property type="entry name" value="PHD_BAZ2A_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd15518">
        <property type="entry name" value="PHD_Ecm5p_Lid2p_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.150.60:FF:000016">
        <property type="entry name" value="Putative Lysine-specific demethylase 5B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.60">
        <property type="entry name" value="ARID DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.650">
        <property type="entry name" value="Cupin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001606">
        <property type="entry name" value="ARID_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036431">
        <property type="entry name" value="ARID_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003347">
        <property type="entry name" value="JmjC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003349">
        <property type="entry name" value="JmjN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048615">
        <property type="entry name" value="KDM5_C-hel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013637">
        <property type="entry name" value="Lys_sp_deMease-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019786">
        <property type="entry name" value="Zinc_finger_PHD-type_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004198">
        <property type="entry name" value="Znf_C5HC2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001965">
        <property type="entry name" value="Znf_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019787">
        <property type="entry name" value="Znf_PHD-finger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10694">
        <property type="entry name" value="LYSINE-SPECIFIC DEMETHYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10694:SF33">
        <property type="entry name" value="LYSINE-SPECIFIC DEMETHYLASE 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01388">
        <property type="entry name" value="ARID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02373">
        <property type="entry name" value="JmjC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02375">
        <property type="entry name" value="JmjN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21323">
        <property type="entry name" value="KDM5_C-hel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00628">
        <property type="entry name" value="PHD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08429">
        <property type="entry name" value="PLU-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02928">
        <property type="entry name" value="zf-C5HC2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01014">
        <property type="entry name" value="ARID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00501">
        <property type="entry name" value="BRIGHT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00558">
        <property type="entry name" value="JmjC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00545">
        <property type="entry name" value="JmjN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00249">
        <property type="entry name" value="PHD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46774">
        <property type="entry name" value="ARID-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51011">
        <property type="entry name" value="ARID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51184">
        <property type="entry name" value="JMJC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51183">
        <property type="entry name" value="JMJN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01359">
        <property type="entry name" value="ZF_PHD_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50016">
        <property type="entry name" value="ZF_PHD_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0408">Iron</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="19" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="11" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0677">Repeat</keyword>
    <keyword evidence="19" id="KW-0808">Transferase</keyword>
    <keyword evidence="8" id="KW-0862">Zinc</keyword>
    <keyword evidence="7 13" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="JmjN" evidence="17">
        <location>
            <begin position="46"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="domain" description="ARID" evidence="16">
        <location>
            <begin position="111"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="domain" description="PHD-type" evidence="15">
        <location>
            <begin position="228"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="domain" description="JmjC" evidence="18">
        <location>
            <begin position="363"/>
            <end position="529"/>
        </location>
    </feature>
    <feature type="domain" description="PHD-type" evidence="15">
        <location>
            <begin position="1015"/>
            <end position="1064"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="1243"/>
            <end position="1293"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="14">
        <location>
            <begin position="1274"/>
            <end position="1293"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012902"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00048734"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS51011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS51183"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS51184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="OBZ90517.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="1293" mass="149475" checksum="9F2045193858BC3D" modified="2016-11-30" version="1">MRRASKRAHSSTTAGAPFDLKSVRTKAVEDATTHRTQPRIFGLQEAPTFYPTKEEFQDPLSYIEKISVEGEKYGIIKIVPPKDYQPEFSLNTENFRFRTRLQKLNSMEGETRTNVNYLEQLTKYHILTGRPVGKIPQLDKRPIDLYKLKNEVSLRGGVQEVTRLKKWAEIGRVLGYARKQCTSMSNALKTAYQKVILPYEIWYAKHKDDVERVIKKEDRASLDSNDESDTCEICHKNENEEELLLCDGCNRGYHTYCLNPPLTSIPKTDWFCLQCLTAVGKDYGFEDGEEHSLGDFHKACNKFKQDWFAKANGEIRPITEEECENEFWRLVENPHETCEVEYGADLHSTQHGSGFIAAEQMPKGQFDPWNLNVIPVDPQSLFTHIKSDISGMMVPWLYVGMCFSAFCWHNEDHYTYSINYMHWGETKTWYGVPGSDTAKFEDTMRKAVPELFEQQPDLLFQLVTMLSPGRLLKEDVKVYAVDQRPGQFVVTYPKAYHSGFNHGFNFCEAVNFAPGKWVDYGLECVKRYKAFRRQPCFSHDELLVTASQNIKPTDNIEWLKRALVEMQTRELNERNAVRTMALKEKTMSSSEMRNELQCIFCHCYTFLSHIGCTCTEKVGCLEHAAELCTCDLSAKTMYLRFTDTEINDLVEKVAHSGLDPTEWMRRVDKTMSAITKSNFIKRLKELLKEGHEMNAPKDCLDTLKDFTDTVEVWILNTERLLNMRHETQKSNGKRRWEKSKELVEQASEIGVDLPYLDQLKSYFARLSYLEAQLNESLFGSGDVELQTKLYQEGLHLRADSIKFNELKCLVESSSWEERAEKVLYGPFNPKVFRKTIKEAEDIGIRNHPGSLLDRLIRMEEFGKEALQRTENVCKGKEKXELGEEDTLLQLGQHPQNPSFSVTLDPQLMNRLKQSIVRSKQVLVELEDFLLNQCCKPTMPERPSLIDAQRIMSSCRELCFKSDLVTQLSNEISRISTWNEQVRHTFMNGRQKALETVLRETLNNVERITTSEDKQGLYCICRKSEAGLMIECDICREWYHGSCVKVPRNVMRSSHSYVCLVCHTSESTKKITHLSRQPKLEEIVELIHAADVFKFRPKDYDYVYKIYQTMQSYRDRVQAFCRSRTQLGIEDIPKIKYYLRTLVGLEVCLQDETEFLRAKIQSLAPVQLPLPVGHNQATSPLDVDLSYMNNDVSMYADERNGYENKSSHPQRNNLYRTDLVEPLQTNESQSSSYLPADNMKRQLEENHTASPKPQKIIKLTVKPPSQPKKPIHPSPTFNNSIHNGILTTNKKQQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NNB4</accession>
    <name>A0A1C7NNB4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Nucleolar protein 13</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">NOP13</name>
        <name evidence="5" type="ORF">A0J61_03192</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000133">
        <property type="protein sequence ID" value="OBZ88754.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NNB4"/>
    <dbReference type="FunCoup" id="A0A1C7NNB4">
        <property type="interactions" value="398"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NNB4"/>
    <dbReference type="InParanoid" id="A0A1C7NNB4"/>
    <dbReference type="OrthoDB" id="439808at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23236">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 4B/4H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23236:SF95">
        <property type="entry name" value="NUCLEOLAR PROTEIN 13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="4">
        <location>
            <begin position="120"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="4">
        <location>
            <begin position="225"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="203"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="305"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="42"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="60"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="76"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="97"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="203"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="324"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="350"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="366"/>
            <end position="375"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OBZ88754.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="400" mass="46330" checksum="502F3D12A52B1A63" modified="2016-11-30" version="1">MAKKESKEEAFNVLTEVTEYEKDEEEEARLAAKAEKKKRKQLSKEEKEAQRKINRENREKKKQKKELNKKRKRGELDEEEAEEEEKEEEDSEMQADSAKKDKKESERPAKPEKKQKVIEYGVWVGNLSYATTSDTIRDFFKECGEIIRLKCPKGNGAKNNNKGFAYVFFSTPEASAKAVALSEQKLEGRSLLIKDSENFERVDDSKPMTEVEKKEMKKQKNPPSPTLFLGNLSFDTTKESIQEHFSWAGEIRKVRLATFEDSGKCKGFAYVDYHEVEAATKAIRAPDKHNLDGRKIRVEFASAEAHMRSKPWLMRKAKKDNGSEQPEQQQQQQQQSESTEEPTFKRRKTFNKEESDHRPRERRPKKPVDSGRLKPGEALSSAQRQKPTVQEFKGTKVVFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NNQ0</accession>
    <name>A0A1C7NNQ0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Ammonia transport outward protein 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">ATO2_0</name>
        <name evidence="7" type="ORF">A0J61_01325</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the acetate uptake transporter (AceTr) (TC 2.A.96) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000040">
        <property type="protein sequence ID" value="OBZ90628.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NNQ0"/>
    <dbReference type="FunCoup" id="A0A1C7NNQ0">
        <property type="interactions" value="57"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NNQ0"/>
    <dbReference type="InParanoid" id="A0A1C7NNQ0"/>
    <dbReference type="OrthoDB" id="3648309at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015123">
        <property type="term" value="F:acetate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051633">
        <property type="entry name" value="AceTr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000791">
        <property type="entry name" value="Gpr1/Fun34/SatP-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF038013">
        <property type="entry name" value="AceTr_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31123">
        <property type="entry name" value="ACCUMULATION OF DYADS PROTEIN 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31123:SF1">
        <property type="entry name" value="ACCUMULATION OF DYADS PROTEIN 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01184">
        <property type="entry name" value="Gpr1_Fun34_YaaH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="75"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="106"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="141"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="164"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="189"/>
            <end position="211"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005587"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OBZ90628.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="230" mass="24307" checksum="6D5D26641D0D4C3C" modified="2016-11-30" version="1">MSAATAPSTQQLPANTNQDVEAKYHAPAYPPVPIYAPPIIANPGPLGLSSFALTTFVLSLHNAGAGVPANGPNEVVVGLALFYGGVVQILAGMWEFRTGNTFGATAFSSYGGFWLSFACILIPSFNITASYTDTAVLEKSLGIYLMSWALFTGLLLIASHRSSIGLMSLFFFLFITFILLAAAKFNDSLTTQVAGGAFGVITALIAWYNALSGLLTKDSSYFLLPTGRLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NPX5</accession>
    <name>A0A1C7NPX5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_01464</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000047">
        <property type="protein sequence ID" value="OBZ90486.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NPX5"/>
    <dbReference type="InParanoid" id="A0A1C7NPX5"/>
    <dbReference type="OrthoDB" id="2357632at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="268"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="282"/>
            <end position="291"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ90486.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="455" mass="52647" checksum="CC7CF764347162A4" modified="2016-11-30" version="1">MVASTQTLSQHNTASDSFSSFLESFGQICSAEQMELCQKLGILSKSEQQHAYRMAKALIEDQQIPVDMEDWHHLTEWVMMLRDRYIIQIESQCIRQHTNDLERIGYLDEVQRLSHLLEEYSHAHEDLTDLLQALKKLTSEWKHRKRDVENIVLSILSSSALKDPDYRVVRVTRSHLNTLGLGLSSIGKYYIVYESLMTDDDRKVILNNVARDFGLVFQENAAQNLARMAGSYHRIFQEEEEVDVMDQIQKLTQQVFIKRPRSVILPYPSSLPTHPSKVPTDVPSTSQSPVSRGSFLERRKSVILMEDENRSEGVENSDLKLPMVFNMSTPLFEPAGWDWPFMLKHKRTRLGDTVSYYWCHPCDHQLSEGQKESAHHAGVWSTSVSRLAEHFAKTGQAYYANMHNNARLMHSHRAQMFEFATHSLMKTYRALQLEQGCANLNRTLTFLYRLQQEHA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NPY1</accession>
    <name>A0A1C7NPY1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Transcription factor Dp-1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">Tfdp1_1</name>
        <name evidence="9" type="ORF">A0J61_00770</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the E2F/DP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000019">
        <property type="protein sequence ID" value="OBZ91175.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NPY1"/>
    <dbReference type="STRING" id="101091.A0A1C7NPY1"/>
    <dbReference type="InParanoid" id="A0A1C7NPY1"/>
    <dbReference type="OrthoDB" id="552115at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005667">
        <property type="term" value="C:transcription regulator complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000977">
        <property type="term" value="F:RNA polymerase II transcription regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051726">
        <property type="term" value="P:regulation of cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.10:FF:000360">
        <property type="entry name" value="Transcription factor Dp-1, a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.140.80">
        <property type="entry name" value="Transcription factor DP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037241">
        <property type="entry name" value="E2F-DP_heterodim"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003316">
        <property type="entry name" value="E2F_WHTH_DNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038168">
        <property type="entry name" value="TF_DP_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014889">
        <property type="entry name" value="Transc_factor_DP_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015648">
        <property type="entry name" value="Transcrpt_fac_DP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12548">
        <property type="entry name" value="TRANSCRIPTION FACTOR DP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12548:SF9">
        <property type="entry name" value="TRANSCRIPTION FACTOR DP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08781">
        <property type="entry name" value="DP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02319">
        <property type="entry name" value="WHD_E2F_TDP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01372">
        <property type="entry name" value="E2F_TDP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144074">
        <property type="entry name" value="E2F-DP heterodimerization region"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6 7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7" id="KW-0804">Transcription</keyword>
    <keyword evidence="3 7" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="E2F/DP family winged-helix DNA-binding" evidence="8">
        <location>
            <begin position="133"/>
            <end position="207"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010940"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003796"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM01372"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OBZ91175.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="320" mass="36444" checksum="F48AF0653F4681AC" modified="2016-11-30" version="1">MSIYQEPTVVKLPPIKLPPLYNSRDDKSNILPSMLMLPDRCQDNHSLLLPPILSSNIPLSPPFSSCSSLSSSSLPPSPNSVAEVNFSSLPKKGSIQSLLNSAQCPMVNKKRKRQLKPQQSQQRFHQPYHKDARPTKGLRLFSKQVCDKVAEKGITTYNQVADELAAEIHQHSNVDQKNIRRRVYDALNVLMALDIIAKDRKQIKWLGMPTNDLEKEIEREESRHKELLETVQRSRHVLNDTLVNFTRLEKLVQRNRQEQQANAPQTVVRLPFFMMSSSQDIYTDSNEKEAFVSLGASYAIHQDTDILAKLWPSHQITTVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NQQ4</accession>
    <name>A0A1C7NQQ4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Ribosome-recycling factor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">frr</name>
        <name evidence="7" type="ORF">A0J61_02349</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Necessary for protein synthesis in mitochondria. Functions as a ribosome recycling factor in mitochondria.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the RRF family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000087">
        <property type="protein sequence ID" value="OBZ89604.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NQQ4"/>
    <dbReference type="STRING" id="101091.A0A1C7NQQ4"/>
    <dbReference type="InParanoid" id="A0A1C7NQQ4"/>
    <dbReference type="OrthoDB" id="407355at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043023">
        <property type="term" value="F:ribosomal large subunit binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1360.40:FF:000001">
        <property type="entry name" value="Ribosome-recycling factor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1360.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.132.20">
        <property type="entry name" value="Ribosome-recycling factor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002661">
        <property type="entry name" value="Ribosome_recyc_fac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023584">
        <property type="entry name" value="Ribosome_recyc_fac_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036191">
        <property type="entry name" value="RRF_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20982:SF3">
        <property type="entry name" value="MITOCHONDRIAL RIBOSOME RECYCLING FACTOR PSEUDO 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20982">
        <property type="entry name" value="RIBOSOME RECYCLING FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01765">
        <property type="entry name" value="RRF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55194">
        <property type="entry name" value="Ribosome recycling factor, RRF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ribosome recycling factor" evidence="6">
        <location>
            <begin position="95"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="52"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="175"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="219"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="61"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="180"/>
            <end position="189"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00024909"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01765"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OBZ89604.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="257" mass="28702" checksum="611DDC78D7393C4D" modified="2016-11-30" version="1">MASRILRSVVTAHSLRSTLTLTSKPRVLAIASTVAWRQPVVCTSVRFYAKKSKDNKKKSGGTESKATSASDSEEPDLQFSEKQIEDRFEQSISQLKEHLSSMRIGRANPSLLDNVRVRIESSHFSLKDLAQVTIRDPQTLMVTVHDADYAAAVEKSIREAGLNLNPIVDSKGIKVPIPKPSRESRDKMAKLVSTTGEQTKTKIRSIRQDGMKQLKHDSKHESADKIKKLEKVVQNLTDKSNKTIDELLKAKIKEVQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NQT7</accession>
    <name>A0A1C7NQT7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">MICOS complex subunit mic19</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_00585</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000013">
        <property type="protein sequence ID" value="OBZ91388.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NQT7"/>
    <dbReference type="STRING" id="101091.A0A1C7NQT7"/>
    <dbReference type="InParanoid" id="A0A1C7NQT7"/>
    <dbReference type="OrthoDB" id="5544375at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012471">
        <property type="entry name" value="DUF1690"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07956">
        <property type="entry name" value="DUF1690"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="52"/>
            <end position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ91388.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="160" mass="18331" checksum="BFCA9F4F2DE2591B" modified="2016-11-30" version="1">MGASQSTAQEPVIFYNPNVPLQFSHSLIGSIEKKVEQTAERREARQVESIVRQRVAEELKKIEQTETQLKQSVYDDLTEKDQLKDKGASELKNDVEAMKQRLSRSAAKEVPTSVKKYQDEVIACFKKNKDRSLDCWEEVASFKQAVAEEQKKFIGSTYQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NR24</accession>
    <name>A0A1C7NR24_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_00477</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000010">
        <property type="protein sequence ID" value="OBZ91478.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NR24"/>
    <dbReference type="STRING" id="101091.A0A1C7NR24"/>
    <dbReference type="InParanoid" id="A0A1C7NR24"/>
    <dbReference type="OrthoDB" id="9932926at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="345"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="10"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="122"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="346"/>
            <end position="357"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ91478.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="374" mass="43922" checksum="2E3D6C50C5925BC5" modified="2016-11-30" version="1">MQNFENLDRLMKQSNQIGELKEELETIKKDTEAHYEDLLAEKDQLIYQSQQRIEELENRKQQESIVESLSVQEDKHLDIKTVNELQRQLEEKDKFIYQQKAEFDELKAQWEVERAELVRPALEQVTEQLDELKRTNKVVVERLNEKEDELAELRAELSRKDREPIKSTSAFNEREKRLNRLTIDLENDRLLAQKLEDLNQQLEAQKQKHEAILKTHAQVIAEKDKVLLQHQKSLDQLKRGHENATKSLEEEQRRNIQKLEIKHQHDIEALTKRLKQAESQAKNHINDELDQLLVEFEQSQHNHTVELADLQKSHQEQLSVMKRGQQEEIASLMNQGKVNNFFKAQGSASSIPTSPRSASKLKDNTKFSWPPVTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NRC8</accession>
    <name>A0A1C7NRC8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Alpha-1,2 mannosyltransferase KTR1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">KTR1_2</name>
        <name evidence="5" type="ORF">A0J61_00979</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the glycosyltransferase 15 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000026">
        <property type="protein sequence ID" value="OBZ90976.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NRC8"/>
    <dbReference type="STRING" id="101091.A0A1C7NRC8"/>
    <dbReference type="InParanoid" id="A0A1C7NRC8"/>
    <dbReference type="OrthoDB" id="439943at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000026">
        <property type="term" value="F:alpha-1,2-mannosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000032">
        <property type="term" value="P:cell wall mannoprotein biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006487">
        <property type="term" value="P:protein N-linked glycosylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.550.10:FF:000051">
        <property type="entry name" value="Alpha-1,2-mannosyltransferase (Ktr4)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="entry name" value="Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002685">
        <property type="entry name" value="Glyco_trans_15"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31121">
        <property type="entry name" value="ALPHA-1,2 MANNOSYLTRANSFERASE KTR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31121:SF2">
        <property type="entry name" value="MANNOSYLTRANSFERASE KTR5-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01793">
        <property type="entry name" value="Glyco_transf_15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF018153">
        <property type="entry name" value="Glyco_trans_15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0808">Transferase</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="7"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="3">
        <location>
            <position position="311"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR018153-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OBZ90976.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="445" mass="51611" checksum="0F06E1A2E7DB70E5" modified="2016-11-30" version="1">MKRGASYILTLVSIVLLFFGSLYFVAKRPSENCLNSLKTSDLLNRESAEFQVPLVSDDQIEAVQEEPLPEPIFKQAQVFPTKETSPASSKSSCLPGSSLLNSQKREKAVIVVLVRNNEVGAMRRTMRDFEDRFNRKFNYPYVFLNDEPFTDEFKNAMLAMTNADVKFGLVPNQMWSVPKHVNETVMNQQLSDYAARGVMYGGSLSYRHMCRFNSGFFYRHPLLDEYDYYWRVEPGVSFYCDLDYDPFTYLRENGKEYGFTITLKEIPETIPTLWQHTMDFARKHQLNTTLLRFFGQPNGGYNLCHFWSNFEIASLNLWRDERYQAYFDYLDSTGNFFYERWGDAIVHSLAAGLFLNKSQVHFFNDIGYRHDHFTHCADDGPLGKCMCPESYQNADNMWGSCLADWKNYAEEGHRWDFRSNGDQIVDFGQVLYANPPAPLANEQAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NRH1</accession>
    <name>A0A1C7NRH1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Nascent polypeptide-associated complex subunit alpha-like UBA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_00184</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000004">
        <property type="protein sequence ID" value="OBZ91727.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NRH1"/>
    <dbReference type="STRING" id="101091.A0A1C7NRH1"/>
    <dbReference type="InParanoid" id="A0A1C7NRH1"/>
    <dbReference type="OrthoDB" id="285219at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043066">
        <property type="term" value="P:negative regulation of apoptotic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050821">
        <property type="term" value="P:protein stabilization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd14361">
        <property type="entry name" value="UBA_HYPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.10">
        <property type="entry name" value="DNA helicase RuvA subunit, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052617">
        <property type="entry name" value="Huntingtin-int_K"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038922">
        <property type="entry name" value="HYPK_UBA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044034">
        <property type="entry name" value="NAC-like_UBA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31184:SF2">
        <property type="entry name" value="HUNTINGTIN-INTERACTING PROTEIN K"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31184">
        <property type="entry name" value="HUNTINGTIN-INTERACTING PROTEIN K FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19026">
        <property type="entry name" value="UBA_HYPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nascent polypeptide-associated complex subunit alpha-like UBA" evidence="2">
        <location>
            <begin position="65"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF19026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ91727.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="105" mass="11756" checksum="91BEB38A5497C3FD" modified="2016-11-30" version="1">MAHDHHDHSNCNHDHGSPKDLKKANDEINLRQQAAEKLAKSLVELQTMANEHKKHVQLKVPAHAVDKSDVELLIKEMQLNKAEAEIALKKHQGDLVATLTDLVAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NRS7</accession>
    <name>A0A1C7NRS7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">SET domain-containing protein 8</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">set8</name>
        <name evidence="2" type="ORF">A0J61_00121</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000002">
        <property type="protein sequence ID" value="OBZ91835.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NRS7"/>
    <dbReference type="FunCoup" id="A0A1C7NRS7">
        <property type="interactions" value="198"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NRS7"/>
    <dbReference type="InParanoid" id="A0A1C7NRS7"/>
    <dbReference type="OrthoDB" id="441812at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016279">
        <property type="term" value="F:protein-lysine N-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd10527">
        <property type="entry name" value="SET_LSMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1410.10">
        <property type="entry name" value="set domain protein methyltransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001214">
        <property type="entry name" value="SET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046341">
        <property type="entry name" value="SET_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050600">
        <property type="entry name" value="SETD3_SETD6_MTase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13271">
        <property type="entry name" value="UNCHARACTERIZED PUTATIVE METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00856">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82199">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50280">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SET" evidence="1">
        <location>
            <begin position="16"/>
            <end position="229"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ91835.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="422" mass="47970" checksum="4294D552258511C7" modified="2016-11-30" version="1">MDQFLKWVQSKGITHDRAQLKKISDDTGYGLFCSQDTPEPSTMVHIPSSLLITSTLALQVSPAFRDTLKQHFDLSLDVLSLAEQRQVLTLFLVYCQYINQNTIWSDYLSILPPVQFFEDHHVLFQPHLLEGTSLWHAVRAKLARLEQVHASLSIDWLSQVTLPMLLWADAVLWSRVVEIEPDQLALIPFFDFANHSQTPNLRWERSSNGIVLVNTEAVGADQELMLSYGSKPNQELLFIHGFCIPNNSVVSVVSLPCMPFFVNDPPRALWLRQTTPQSTLRLGLTDNEREGIERAGWDWTSMMIMYLAVLDSDEVEMAFTENGLELEGQTVTSLSELEQVVRSFEYFPVIQLRAIVLLIQALEYQLEQASPITNHTSPLSSQVAIYQTEEQQIIHRSLEVLTELQSQLMTDPVVQAFLQANS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NS15</accession>
    <name>A0A1C7NS15_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 10">Fructose-bisphosphate aldolase</fullName>
            <shortName evidence="10">FBP aldolase</shortName>
            <ecNumber evidence="5 10">4.1.2.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">fba_0</name>
        <name evidence="11" type="ORF">A0J61_00176</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 10">Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 10">
            <text>beta-D-fructose 1,6-bisphosphate = D-glyceraldehyde 3-phosphate + dihydroxyacetone phosphate</text>
            <dbReference type="Rhea" id="RHEA:14729"/>
            <dbReference type="ChEBI" id="CHEBI:32966"/>
            <dbReference type="ChEBI" id="CHEBI:57642"/>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
            <dbReference type="EC" id="4.1.2.13"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="10">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="10">Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3 10">Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose: step 4/4.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 10">Belongs to the class II fructose-bisphosphate aldolase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.1.2.13" evidence="5 10"/>
    <dbReference type="EMBL" id="LUGH01000004">
        <property type="protein sequence ID" value="OBZ91760.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NS15"/>
    <dbReference type="FunCoup" id="A0A1C7NS15">
        <property type="interactions" value="362"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NS15"/>
    <dbReference type="InParanoid" id="A0A1C7NS15"/>
    <dbReference type="OrthoDB" id="35652at2759"/>
    <dbReference type="UniPathway" id="UPA00109">
        <property type="reaction ID" value="UER00183"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004332">
        <property type="term" value="F:fructose-bisphosphate aldolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006094">
        <property type="term" value="P:gluconeogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006096">
        <property type="term" value="P:glycolytic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd00946">
        <property type="entry name" value="FBP_aldolase_IIA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.70:FF:000013">
        <property type="entry name" value="Class II fructose-bisphosphate aldolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000771">
        <property type="entry name" value="FBA_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006411">
        <property type="entry name" value="Fruct_bisP_bact"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00167">
        <property type="entry name" value="cbbA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01520">
        <property type="entry name" value="FruBisAldo_II_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006628">
        <property type="entry name" value="PRK09197.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30559:SF0">
        <property type="entry name" value="FRUCTOSE-BISPHOSPHATE ALDOLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30559">
        <property type="entry name" value="FRUCTOSE-BISPHOSPHATE ALDOLASE CLASS 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01116">
        <property type="entry name" value="F_bP_aldolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001359">
        <property type="entry name" value="F_bP_aldolase_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51569">
        <property type="entry name" value="Aldolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00602">
        <property type="entry name" value="ALDOLASE_CLASS_II_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00806">
        <property type="entry name" value="ALDOLASE_CLASS_II_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 10" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="9 10" id="KW-0456">Lyase</keyword>
    <keyword evidence="6 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 10" id="KW-0862">Zinc</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005812"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00013068"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU366023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="OBZ91760.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="365" mass="40354" checksum="0DE53F98088B7C4A" modified="2016-11-30" version="1">MGLLDIVPAGVVTGKNLLKLFEYASFSLLTAREHKFAIPAINCTSTSTVNAALEAARDIKSPIIIQFSQGGAAYFAGKGLDNKNQEASIMGAVAGAQYVRAVAKAYGIPVVVHSDHCAKKLLPWFDGMLAADEQYYKAHGEPLFSSHMLDLSEESKEENIEICLKYLKRMAAIDCWLEMEIGITGGEEDGVDNSGVDNAALYTQPEDIWDIYKAFKEVTSLFSIAAGFGNVHGVYAPGNVKLHPELLGKHQQYVREQLKNDDVKPVFFVFHGGSGSTENDIAEAVRNGVVKMNVDTDTQWAYWEGLKNYYEGKKDYLQSQVGNPEGDNKPNKKHYDPRVFIREAEKSMTKRVQQACKDLGNVDRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NS38</accession>
    <name>A0A1C7NS38_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 5">Kynureninase</fullName>
            <ecNumber evidence="4 5">3.7.1.3</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">Biosynthesis of nicotinic acid protein 5</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="4">L-kynurenine hydrolase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">kynu_0</name>
        <name evidence="4" type="synonym">BNA5</name>
        <name evidence="6" type="ORF">A0J61_00030</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4 5">Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-hydroxyanthranilic acid (3-OHAA), respectively.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>3-hydroxy-L-kynurenine + H2O = 3-hydroxyanthranilate + L-alanine + H(+)</text>
            <dbReference type="Rhea" id="RHEA:25143"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:36559"/>
            <dbReference type="ChEBI" id="CHEBI:57972"/>
            <dbReference type="ChEBI" id="CHEBI:58125"/>
            <dbReference type="EC" id="3.7.1.3"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4 5">
            <text>L-kynurenine + H2O = anthranilate + L-alanine + H(+)</text>
            <dbReference type="Rhea" id="RHEA:16813"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16567"/>
            <dbReference type="ChEBI" id="CHEBI:57959"/>
            <dbReference type="ChEBI" id="CHEBI:57972"/>
            <dbReference type="EC" id="3.7.1.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="4 5">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="4 5">Amino-acid degradation; L-kynurenine degradation; L-alanine and anthranilate from L-kynurenine: step 1/1.</text>
    </comment>
    <comment type="pathway">
        <text evidence="4 5">Cofactor biosynthesis; NAD(+) biosynthesis; quinolinate from L-kynurenine: step 2/3.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4 5">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4 5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 5">Belongs to the kynureninase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.7.1.3" evidence="4 5"/>
    <dbReference type="EMBL" id="LUGH01000001">
        <property type="protein sequence ID" value="OBZ91945.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NS38"/>
    <dbReference type="STRING" id="101091.A0A1C7NS38"/>
    <dbReference type="InParanoid" id="A0A1C7NS38"/>
    <dbReference type="OrthoDB" id="5978656at2759"/>
    <dbReference type="UniPathway" id="UPA00253">
        <property type="reaction ID" value="UER00329"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00334">
        <property type="reaction ID" value="UER00455"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030429">
        <property type="term" value="F:kynureninase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034354">
        <property type="term" value="P:'de novo' NAD+ biosynthetic process from L-tryptophan"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043420">
        <property type="term" value="P:anthranilate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097053">
        <property type="term" value="P:L-kynurenine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019441">
        <property type="term" value="P:L-tryptophan catabolic process to kynurenine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019805">
        <property type="term" value="P:quinolinate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.640.10:FF:000031">
        <property type="entry name" value="Kynureninase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01970">
        <property type="entry name" value="Kynureninase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010111">
        <property type="entry name" value="Kynureninase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01814">
        <property type="entry name" value="kynureninase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14084">
        <property type="entry name" value="KYNURENINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14084:SF0">
        <property type="entry name" value="KYNURENINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22580">
        <property type="entry name" value="KYNU_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF038800">
        <property type="entry name" value="KYNU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 4 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1 4 5" id="KW-0662">Pyridine nucleotide biosynthesis</keyword>
    <keyword evidence="3 4 5" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="4">
        <location>
            <position position="133"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="134"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="161"/>
            <end position="164"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="216"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="245"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="248"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="270"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="301"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="329"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="4">
        <location>
            <position position="271"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRNR" id="PIRNR038800"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OBZ91945.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="457" mass="51577" checksum="47D845039608D98F" modified="2016-11-30" version="1">MEKLDDLIQKAGYKLGSFELAETLDAQDRFNSFRDEFVIPSRKDVATKQPVIEREGELEEACTYLCGNSLGLMPKRSRELIYEELDAWGRKGIEGQWSHPYQRPWATSDERVKGHLARIVGAKPVEVTSMNTLTINIHSMLATFYQPTGSRFKILIEKKAFPSDHYAVTSHLQSRGIDPDAGLLMIAPRPGEHTLRTEDIIDLIHKDKDIALVMLSGIQYYTGQFFEMEKITKAGHDAGCIVGWDLAHAVGNVPLQLHDWDVDFACWCTYKYLNSGPGGIGGVFIHEKYKNDTSRPRLAGWWGYQKETRFEMLPDFVPSEGAAGFQVSTPSAFTNTSLLGSLEVFEAAGGVSALFQKSRLLTGYLEKLLQSEFSNEFKNEVIRILTPSDPNQRGCQLSLEFPEKTAEVFQGLCDRGIVVDQRKPTVIRVAPAPLYNTFKDVHRFVMQLKKVMKQVYH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7LS84</accession>
    <name>A0A1C7LS84_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_11928</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01002710">
        <property type="protein sequence ID" value="OBZ65644.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7LS84"/>
    <dbReference type="InParanoid" id="A0A1C7LS84"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="35"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ65644.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="97" mass="11530" checksum="9D04D508BED56137" modified="2016-11-30" version="1" fragment="single">NAWKQLRTLADISRTPTYRYDDFWLENMILARYYHNKSRKEPQKSARKKASKNKSDKGSKATKRQKKVSAYMTMNSNKATLPRLHHRLNKNQYQVGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MV50</accession>
    <name>A0A1C7MV50_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_11239</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001814">
        <property type="protein sequence ID" value="OBZ80712.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="InParanoid" id="A0A1C7MV50"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="80"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="86"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="110"/>
            <end position="122"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ80712.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="129" mass="14572" checksum="ED1240B2236D550D" modified="2016-11-30" version="1">MEIVDALVGEGITWRAVESVKTFVRNXEDSYKKAIDWKNGTGNWVMRSYEEEGLSQEECSNRIMNNDDVAAIIDQATNRRKRVATEIEDSQSADEDEMEQFATDDESDDPSTSRTVNFSSAAPLQKTKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MVF2</accession>
    <name>A0A1C7MVF2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">ATP-dependent DNA helicase</fullName>
            <ecNumber evidence="1">5.6.2.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">pif1_2</name>
        <name evidence="3" type="ORF">A0J61_11139</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="5.6.2.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the helicase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.6.2.3" evidence="1"/>
    <dbReference type="EMBL" id="LUGH01001708">
        <property type="protein sequence ID" value="OBZ80812.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MVF2"/>
    <dbReference type="STRING" id="101091.A0A1C7MVF2"/>
    <dbReference type="InParanoid" id="A0A1C7MVF2"/>
    <dbReference type="OrthoDB" id="1728974at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043139">
        <property type="term" value="F:5'-3' DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000723">
        <property type="term" value="P:telomere maintenance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010285">
        <property type="entry name" value="DNA_helicase_pif1-like_DEAD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10492">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10492:SF95">
        <property type="entry name" value="HELITRON HELICASE-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05970">
        <property type="entry name" value="PIF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0227">DNA damage</keyword>
    <keyword evidence="1" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="1" id="KW-0234">DNA repair</keyword>
    <keyword evidence="1 3" id="KW-0347">Helicase</keyword>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA helicase Pif1-like DEAD-box helicase" evidence="2">
        <location>
            <begin position="288"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="519"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU363044"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF05970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ80812.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="519" mass="58627" checksum="9D6AB908A5C5F15D" modified="2016-11-30" version="1" fragment="single">GRYIGPTEAFARLFEYKMHEEDPTVASLAFHLPNEQPVYFPEDANTPEIHPTCGERFYLRLLLVNIAGSKSFNDLKTVNGSQCSTFKQACLQLHLIEEGQGWIHYFEEASLFSSGDSFRSLFVTTLNFGQLIDPHTLWMQFHNSMCDDLVHKLQLLFLQNQLNTSTDDSAFYDGHPPLGYGLHLIDSKLIELSRSLDEFGLPTFKHDWINALNRGTSLEFSDQKYAFDTIVDKLQSTDLLNDTSLANSENAISFFLHGPAGTGKTFVYNTLSNYLRSQCKIVLCVTSSVNETSSCYIPKNSGLAELLRKTDLIIRNEVPMQNKRCFEAVDRTLKDIGSNNTLFGGLLVLLGGDFAQIPPVVRHGNRSAIVEASVEQSYIWPQSQVLYLKHNMRARGTSTNEIYFKKWLHLITYNKLIQNARVPPPQYIPQTYSLDELIYRVYPAQMLNEALNNSSSLCNSAILTSRNDTVDAINQKVLDMMPSEAVTLISADKADYSDDENANNKLYRVSNEYLQTLGP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MVU4</accession>
    <name>A0A1C7MVU4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_11018</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001591">
        <property type="protein sequence ID" value="OBZ80933.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MVU4"/>
    <dbReference type="STRING" id="101091.A0A1C7MVU4"/>
    <dbReference type="InParanoid" id="A0A1C7MVU4"/>
    <dbReference type="OrthoDB" id="2299889at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="188"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ80933.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="188" mass="21512" checksum="D3450ACD14C26D18" modified="2016-11-30" version="1" fragment="single">MANYSFEIVMDEHCFAAEYQDMYVEQTLARELRDNFVKIVDMDGTSASDNIPHNEVQQLVTLSEYKPSVFSVSAPKQKKIVNAEKAPTAAQVTKRQYRKYTEQQIEELFCLVFEEGKTAAEAARATGIVVRTGQDYVQKARLFLEEERIAEEEEVDSDEEVVPPVPSVLKDRKHGSQKLFQAYSLFFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MVY1</accession>
    <name>A0A1C7MVY1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">DNA repair protein RAD51 homolog</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">RAD51_0</name>
        <name evidence="10" type="ORF">A0J61_10988</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Required both for recombination and for the repair of DNA damage caused by X-rays.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the RecA family. RAD51 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001568">
        <property type="protein sequence ID" value="OBZ80962.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MVY1"/>
    <dbReference type="STRING" id="101091.A0A1C7MVY1"/>
    <dbReference type="InParanoid" id="A0A1C7MVY1"/>
    <dbReference type="OrthoDB" id="10251254at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000794">
        <property type="term" value="C:condensed nuclear chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140664">
        <property type="term" value="F:ATP-dependent DNA damage sensor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000150">
        <property type="term" value="F:DNA strand exchange activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003690">
        <property type="term" value="F:double-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042802">
        <property type="term" value="F:identical protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070192">
        <property type="term" value="P:chromosome organization involved in meiotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000730">
        <property type="term" value="P:DNA recombinase assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042148">
        <property type="term" value="P:DNA strand invasion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006312">
        <property type="term" value="P:mitotic recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990426">
        <property type="term" value="P:mitotic recombination-dependent replication fork processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007131">
        <property type="term" value="P:reciprocal meiotic recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000723">
        <property type="term" value="P:telomere maintenance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd19513">
        <property type="entry name" value="Rad51"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.150.20:FF:000008">
        <property type="entry name" value="DNA repair protein RAD51 homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000092">
        <property type="entry name" value="DNA repair protein Rad51 homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.20">
        <property type="entry name" value="5' to 3' exonuclease, C-terminal subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011941">
        <property type="entry name" value="DNA_recomb/repair_Rad51"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016467">
        <property type="entry name" value="DNA_recomb/repair_RecA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010995">
        <property type="entry name" value="DNA_repair_Rad51/TF_NusA_a-hlx"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013632">
        <property type="entry name" value="Rad51_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020588">
        <property type="entry name" value="RecA_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020587">
        <property type="entry name" value="RecA_monomer-monomer_interface"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003301">
        <property type="entry name" value="PRK04301.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02239">
        <property type="entry name" value="recomb_RAD51"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22942:SF39">
        <property type="entry name" value="DNA REPAIR PROTEIN RAD51 HOMOLOG 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22942">
        <property type="entry name" value="RECA/RAD51/RADA DNA STRAND-PAIRING FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08423">
        <property type="entry name" value="Rad51"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005856">
        <property type="entry name" value="Rad51"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47794">
        <property type="entry name" value="Rad51 N-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50162">
        <property type="entry name" value="RECA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50163">
        <property type="entry name" value="RECA_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0227">DNA damage</keyword>
    <keyword evidence="7" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="7" id="KW-0234">DNA repair</keyword>
    <keyword evidence="7" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5 7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RecA family profile 1" evidence="8">
        <location>
            <begin position="98"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="domain" description="RecA family profile 2" evidence="9">
        <location>
            <begin position="276"/>
            <end position="339"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007095"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003422"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU364139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50162"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OBZ80962.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="339" mass="37312" checksum="2D135782ACB52394" modified="2016-11-30" version="1">MSTQNRIEDELKKDTEEEATGALVVNELERHGIHQTDIKRLQEAGFYTIDAIAYSPRKALLAIKGFSEAKVDKIMKEVSCLINIGFTTALDIQTRRNELIFITTGSKELDRLLGGGIETGSITELFGEFRCGKTQLCLTLAVSCQLALEHGGAEGKCLFIDTEGTFRPNRILSIASRFGLDAETCLNNIAYARAYNTDHQTSLLVQACAMMAETRFGLLIVDSVISLYRTDFPGRGELSARQMHLARFLRSLQRIADEFGVAVVLTNQMLATVDGGVMFTADPKKPTGGNIMAHACCTRLQLRKGRAENRVCRVYDSPSLPESEATFAISEEGIVDAQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MWE3</accession>
    <name>A0A1C7MWE3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_10824</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001422">
        <property type="protein sequence ID" value="OBZ81127.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MWE3"/>
    <dbReference type="InParanoid" id="A0A1C7MWE3"/>
    <dbReference type="OrthoDB" id="2273311at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="104"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ81127.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="104" mass="11734" checksum="557D4F8C2A24C478" modified="2016-11-30" version="1" fragment="single">WQSVWNLFFEGTVDLSQNALPVKQAVFALHFPPLQSSTTTRYASVVIGSTIQSLWRAHWSFVFDSRPFTVSTILAQTRLLINAATEEDFVLRGIPHCPLPFLSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MWF0</accession>
    <name>A0A1C7MWF0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_11192</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001763">
        <property type="protein sequence ID" value="OBZ80759.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MWF0"/>
    <dbReference type="InParanoid" id="A0A1C7MWF0"/>
    <dbReference type="OrthoDB" id="2290350at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ80759.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="173" mass="19449" checksum="E16FED7459128498" modified="2016-11-30" version="1">MQFVNSKSANLVSKAAEVYSKACIRIAQILADLNVTYSKSRPNLKNISMQINDKRLGLMQPTIKQGQNFAKTSSSLNSSIISAPTTLDSFSSGSGKQSKLTPFQKGIVVDMFAKLNRTKMRRLSTGTVVEQQMKMFAFECNFEHPVHSMVFDVSDKSWLKYFTPEEIKDIKNH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MXD5</accession>
    <name>A0A1C7MXD5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Retrotransposon gag domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_10845</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001438">
        <property type="protein sequence ID" value="OBZ81106.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MXD5"/>
    <dbReference type="STRING" id="101091.A0A1C7MXD5"/>
    <dbReference type="InParanoid" id="A0A1C7MXD5"/>
    <dbReference type="OrthoDB" id="2289688at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00303">
        <property type="entry name" value="retropepsin_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.70.10">
        <property type="entry name" value="Acid Proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021109">
        <property type="entry name" value="Peptidase_aspartic_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005162">
        <property type="entry name" value="Retrotrans_gag_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13650">
        <property type="entry name" value="Asp_protease_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03732">
        <property type="entry name" value="Retrotrans_gag"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50630">
        <property type="entry name" value="Acid proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Retrotransposon gag" evidence="2">
        <location>
            <begin position="58"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="125"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="354"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="125"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="705"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03732"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ81106.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="705" mass="81484" checksum="2F2E04377CEC0F88" modified="2016-11-30" version="1" fragment="single">MSIKFEIPKFDPEKDDAELWLYRYEKDSRLNNWSKDIRLQYVDNCFNYEMQLWYMRNKFSDWEKFKSNFLQMYGKKIDLDQLTVQIISIKMHPREGIHHYFNRFELLHDQYIQERMKHDNKQVLHSQNNVSSSSETNEAAVQPLEESDDEDNFSLTEREFVKHFINGIASVNLRRLLRGRKLRTMEETMSYIEELQEGEEYLLDEETTLVVDETVKPILHTKNTNQGVIVKSNKTKTEDDVANIVDTFKNMTMMLSEFINNNTKTNSKAFHQDTKKKITCWNCKDTEHKTPDYNKPCKLCGSKEHVHYQCGQYKSSKQTNEFMLIEEMLVSEKRKMVDNDTQAVENKRLRDSRVNRSGNNYDTTPKRRMTNTVPEPLDDQTQKSVPITQNTPKTANEIANKQTKKGRNVGTEQEVEKIVDHILDETSHKLSLRQIGILSAPARSRIKTRLTKSHAKIPLMATTNHNLLTEVYAQDENDRTNMPKCLGAPRTVGTINGQPCEIILDGGSTGCIVSKKLAIKIGLTEAEPTNIKLMFGDGSFVAPIGVINGLQVAIVEVDYRNVSALCLDVGDRYESLIGRQGLYDMKIGTDWAQHYWYISTSSGELPIEVHYRTPFDEESTNDDDSELSDTAYQEGFLIIEDYDEDKHKSYNHKSSIVNNDRISTLIEQISSYDNIDTETKEKLIVLINKYEDCFGTNYSHLSTTN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MXV5</accession>
    <name>A0A1C7MXV5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_10301</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001109">
        <property type="protein sequence ID" value="OBZ81652.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MXV5"/>
    <dbReference type="STRING" id="101091.A0A1C7MXV5"/>
    <dbReference type="InParanoid" id="A0A1C7MXV5"/>
    <dbReference type="OrthoDB" id="10036850at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051055">
        <property type="entry name" value="PIF1_helicase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47642">
        <property type="entry name" value="ATP-DEPENDENT DNA HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47642:SF8">
        <property type="entry name" value="ATP-DEPENDENT DNA HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="230"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ81652.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="230" mass="26775" checksum="9708F3E3DAA95F2E" modified="2016-11-30" version="1" fragment="single">MSRILQRVLEEGVKDNAPTKNLLKTIAAKYYNVCEISAQEAAYNLLSLRMTESSRGVIFVPTGLVGSRARMMKSKEALQNLPEFSSDVFCNGMVEYYSHRLDSLESLNFAGFCAYYQYFAKKRILIRRTNDKDIDEETNNINEEDEVEGGFLELKEGYGFIKRRKKAKVIRYYKPNAQKDSKLYSHHLVMLYLPWRDQFNEIDKQDCQSLFRQNKQAIEEAANEFSKLPD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MYL6</accession>
    <name>A0A1C7MYL6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Peroxidase</fullName>
            <ecNumber evidence="13">1.11.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="primary">CCP1</name>
        <name evidence="16" type="ORF">A0J61_09946</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Destroys radicals which are normally produced within the cells and which are toxic to biological systems.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>2 Fe(II)-[cytochrome c] + H2O2 + 2 H(+) = 2 Fe(III)-[cytochrome c] + 2 H2O</text>
            <dbReference type="Rhea" id="RHEA:16581"/>
            <dbReference type="Rhea" id="RHEA-COMP:10350"/>
            <dbReference type="Rhea" id="RHEA-COMP:14399"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16240"/>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
            <dbReference type="ChEBI" id="CHEBI:29034"/>
            <dbReference type="EC" id="1.11.1.5"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Mitochondrion intermembrane space</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Mitochondrion matrix</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the peroxidase family. Cytochrome c peroxidase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.11.1.-" evidence="13"/>
    <dbReference type="EMBL" id="LUGH01000979">
        <property type="protein sequence ID" value="OBZ82005.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MYL6"/>
    <dbReference type="STRING" id="101091.A0A1C7MYL6"/>
    <dbReference type="InParanoid" id="A0A1C7MYL6"/>
    <dbReference type="OrthoDB" id="2859658at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005758">
        <property type="term" value="C:mitochondrial intermembrane space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004130">
        <property type="term" value="F:cytochrome-c peroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034599">
        <property type="term" value="P:cellular response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042744">
        <property type="term" value="P:hydrogen peroxide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000302">
        <property type="term" value="P:response to reactive oxygen species"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00691">
        <property type="entry name" value="ascorbate_peroxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.520.10:FF:000005">
        <property type="entry name" value="Cytochrome c peroxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.520.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.420.10">
        <property type="entry name" value="Peroxidase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044831">
        <property type="entry name" value="Ccp1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002016">
        <property type="entry name" value="Haem_peroxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010255">
        <property type="entry name" value="Haem_peroxidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002207">
        <property type="entry name" value="Peroxidase_I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019794">
        <property type="entry name" value="Peroxidases_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31356:SF58">
        <property type="entry name" value="CYTOCHROME C PEROXIDASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31356">
        <property type="entry name" value="THYLAKOID LUMENAL 29 KDA PROTEIN, CHLOROPLASTIC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00141">
        <property type="entry name" value="peroxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00459">
        <property type="entry name" value="ASPEROXIDASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00458">
        <property type="entry name" value="PEROXIDASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48113">
        <property type="entry name" value="Heme-dependent peroxidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00436">
        <property type="entry name" value="PEROXIDASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50873">
        <property type="entry name" value="PEROXIDASE_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0349">Heme</keyword>
    <keyword evidence="10" id="KW-0408">Iron</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="9 13" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5 13 16" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="Plant heme peroxidase family profile" evidence="15">
        <location>
            <begin position="131"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="81"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="14">
        <location>
            <begin position="81"/>
            <end position="91"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004305"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005997"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00049265"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU363051"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50873"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="OBZ82005.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="385" mass="43072" checksum="E9758FE5E612F1FA" modified="2016-11-30" version="1">MKSLRSAKLLVTHVGRSSRPRFVTSRQFATMSQSGGSGGGFSPLLWIGCISLGGAFTYYQKQRADRIDASLIEKKGIDVDQSAQEETNQNSKEAKKLGKPAVSDAPKKSIDYQQVYNDIAELLDNDSDYDDGSYGPILLRLAWHSSGTYNADDNSGGSSGGTMRFNAEASHSANNGLEFARDLLHKHIKPKYPELSYGDLYTLGGVVAIQELGGPDIKWRPGRIDAGENKCIPEGRLPDGAKGVDHARDIFYRMGFDDQEIVALTGAHVLGRCHLDRSGFEGPWHEAPTFFNNGYFKSILGREWVKRNLPEGGWQWVDKESPDIMMLPIEITMVEDKKLRPYYELYAKDEEKFFEDFAKAFKKLIELGVPFSGEEKEYVFKRQSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MYU5</accession>
    <name>A0A1C7MYU5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative arrestin-related trafficking adapter C2D10.04</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_10375</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001141">
        <property type="protein sequence ID" value="OBZ81576.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7MYU5"/>
    <dbReference type="InParanoid" id="A0A1C7MYU5"/>
    <dbReference type="OrthoDB" id="2333384at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030674">
        <property type="term" value="F:protein-macromolecule adaptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031625">
        <property type="term" value="F:ubiquitin protein ligase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070086">
        <property type="term" value="P:ubiquitin-dependent endocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.640">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014752">
        <property type="entry name" value="Arrestin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011021">
        <property type="entry name" value="Arrestin-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050357">
        <property type="entry name" value="Arrestin_domain-protein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11188">
        <property type="entry name" value="ARRESTIN DOMAIN CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11188:SF17">
        <property type="entry name" value="FI21816P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00339">
        <property type="entry name" value="Arrestin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="E set domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Arrestin-like N-terminal" evidence="2">
        <location>
            <begin position="34"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="361"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="361"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="488"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ81576.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="488" mass="54635" checksum="9E9D25C1D2836ED5" modified="2016-11-30" version="1" fragment="single">MHLGLLTQERLSFDPIKPLILRGPPTEDSSTVFTGNVVLSLSKSTKINSITVTFKSTATTYWPEGIGARGTRLTHEKILNDESXIILEAKKNEHIKLSAGIHRFPFAFIVPNSIVETIEDVYGRVKHTIDARVIGPGIQLLNNWHISKPVLVLRSYMSDSFLTNNSVQDLSRTYEKHLPTVDIQLVVERAAFSSGDLFYLKLIMQPQRKKVRLDHMELTVTENRRYHVGEANANRTDVEQFQLPYLASVKLMDNEEVEESNDALRSVFDKHGRGVDLVDTIAYRITFATPTCMRNIHHTTYYKDILFKHHLSISMAISYVDEELSSDLFLNRPGLSSNQSSSSSFAEDGLSSLPASAFASASSTPQISPSSSSTTHAKPSMEHHAMPIIAPPPAAFALSSYNTNTHIRQPVVHTSSPAMFFSPPPSQSSHQPLPPPSQPTWLSKLRKPINAKEEGKHVIRKRETIRLETPIGVFDCRLKEDYGRLPSY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MYZ1</accession>
    <name>A0A1C7MYZ1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Endonuclease/exonuclease/phosphatase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_10324</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001119">
        <property type="protein sequence ID" value="OBZ81626.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MYZ1"/>
    <dbReference type="InParanoid" id="A0A1C7MYZ1"/>
    <dbReference type="OrthoDB" id="2282763at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.10.10">
        <property type="entry name" value="Endonuclease/exonuclease/phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036691">
        <property type="entry name" value="Endo/exonu/phosph_ase_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56219">
        <property type="entry name" value="DNase I-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ81626.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="208" mass="23253" checksum="41055E9ED28A6205" modified="2016-11-30" version="1">MEWLNAHNTNCFPDALPTYTSAANHNTRKTIDYVFVDKLWVPNTSNAQIHHLPSSWTDHSLLTVDVSTLEIATGPGAWRFNPTLLLDSRFVQLLTVSVVTFFNRIDFNALQISVTSPPTAPPVPFVASIATKRHRVWESFKLLLQNVTKSYSRHSKARSQHILSCLQLEGNDQLASVSSAVFSDAAHLSRLQQLDTAIETLVEKETAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-06-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MZK0</accession>
    <name>A0A1C7MZK0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_11397</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001988">
        <property type="protein sequence ID" value="OBZ80554.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MZK0"/>
    <dbReference type="InParanoid" id="A0A1C7MZK0"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ80554.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="52" mass="6141" checksum="C24BB8BA68AE4D9C" modified="2016-11-30" version="1" fragment="single">MLPKKHSRLTDNTRNPQHQFRTHSFLWSEHCGIVSLNPNIEIAPEFISIDQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MZS8</accession>
    <name>A0A1C7MZS8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="20">DNA polymerase</fullName>
            <ecNumber evidence="20">2.7.7.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="26" type="primary">pol3</name>
        <name evidence="26" type="ORF">A0J61_09703</name>
    </gene>
    <organism evidence="26 27">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="26 27" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="26 27">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="19 28">
            <text>DNA(n) + a 2'-deoxyribonucleoside 5'-triphosphate = DNA(n+1) + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:22508"/>
            <dbReference type="Rhea" id="RHEA-COMP:17339"/>
            <dbReference type="Rhea" id="RHEA-COMP:17340"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61560"/>
            <dbReference type="ChEBI" id="CHEBI:173112"/>
            <dbReference type="EC" id="2.7.7.7"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 20">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 20">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 20">Belongs to the DNA polymerase type-B family.</text>
    </comment>
    <comment type="caution">
        <text evidence="26">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.7" evidence="20"/>
    <dbReference type="EMBL" id="LUGH01000913">
        <property type="protein sequence ID" value="OBZ82248.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MZS8"/>
    <dbReference type="FunCoup" id="A0A1C7MZS8">
        <property type="interactions" value="586"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7MZS8"/>
    <dbReference type="InParanoid" id="A0A1C7MZS8"/>
    <dbReference type="OrthoDB" id="2414538at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043625">
        <property type="term" value="C:delta DNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008296">
        <property type="term" value="F:3'-5'-DNA exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003887">
        <property type="term" value="F:DNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006287">
        <property type="term" value="P:base-excision repair, gap-filling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045004">
        <property type="term" value="P:DNA replication proofreading"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006297">
        <property type="term" value="P:nucleotide-excision repair, DNA gap filling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05777">
        <property type="entry name" value="DNA_polB_delta_exo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd05533">
        <property type="entry name" value="POLBc_delta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.132.60:FF:000001">
        <property type="entry name" value="DNA polymerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.690:FF:000001">
        <property type="entry name" value="DNA polymerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.10:FF:000351">
        <property type="entry name" value="DNA polymerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.1540">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.132.60">
        <property type="entry name" value="DNA polymerase family B, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.342.10">
        <property type="entry name" value="DNA Polymerase, chain B, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.690">
        <property type="entry name" value="Helix hairpin bin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1600.10">
        <property type="entry name" value="Palm domain of DNA polymerase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006172">
        <property type="entry name" value="DNA-dir_DNA_pol_B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017964">
        <property type="entry name" value="DNA-dir_DNA_pol_B_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006133">
        <property type="entry name" value="DNA-dir_DNA_pol_B_exonuc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006134">
        <property type="entry name" value="DNA-dir_DNA_pol_B_multi_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043502">
        <property type="entry name" value="DNA/RNA_pol_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042087">
        <property type="entry name" value="DNA_pol_B_thumb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023211">
        <property type="entry name" value="DNA_pol_palm_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050240">
        <property type="entry name" value="DNA_pol_type-B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056435">
        <property type="entry name" value="DPOD/Z_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025687">
        <property type="entry name" value="Znf-C4pol"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00592">
        <property type="entry name" value="pol2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10322">
        <property type="entry name" value="DNA POLYMERASE CATALYTIC SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10322:SF23">
        <property type="entry name" value="DNA POLYMERASE DELTA CATALYTIC SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00136">
        <property type="entry name" value="DNA_pol_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03104">
        <property type="entry name" value="DNA_pol_B_exo1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24055">
        <property type="entry name" value="POL3_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14260">
        <property type="entry name" value="zf-C4pol"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00106">
        <property type="entry name" value="DNAPOLB"/>
    </dbReference>
    <dbReference type="SMART" id="SM00486">
        <property type="entry name" value="POLBc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56672">
        <property type="entry name" value="DNA/RNA polymerases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00116">
        <property type="entry name" value="DNA_POLYMERASE_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 20" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="7 20" id="KW-0235">DNA replication</keyword>
    <keyword evidence="17 20" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="14 20" id="KW-0239">DNA-directed DNA polymerase</keyword>
    <keyword evidence="13" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="15 20" id="KW-0408">Iron</keyword>
    <keyword evidence="16 20" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="9 20" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0540">Nuclease</keyword>
    <keyword evidence="6 20" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="18 20" id="KW-0539">Nucleus</keyword>
    <keyword evidence="27" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 20" id="KW-0808">Transferase</keyword>
    <keyword evidence="12 20" id="KW-0862">Zinc</keyword>
    <keyword evidence="10 20" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="DNA polymerase delta/zeta catalytic subunit N-terminal" evidence="25">
        <location>
            <begin position="113"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="domain" description="DNA-directed DNA polymerase family B exonuclease" evidence="23">
        <location>
            <begin position="205"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="domain" description="DNA-directed DNA polymerase family B multifunctional" evidence="22">
        <location>
            <begin position="502"/>
            <end position="933"/>
        </location>
    </feature>
    <feature type="domain" description="C4-type zinc-finger of DNA polymerase delta" evidence="24">
        <location>
            <begin position="970"/>
            <end position="1042"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="21">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="21">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00022932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00049244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="RuleBase" id="RU000442"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="21">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="22">
        <source>
            <dbReference type="Pfam" id="PF00136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="23">
        <source>
            <dbReference type="Pfam" id="PF03104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="24">
        <source>
            <dbReference type="Pfam" id="PF14260"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="25">
        <source>
            <dbReference type="Pfam" id="PF24055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="26">
        <source>
            <dbReference type="EMBL" id="OBZ82248.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="27">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="1063" mass="120787" checksum="F2D6C2D9D41C76FD" modified="2016-11-30" version="1">MSDNITLSSQPFEPGSAMKKRKTKHDLNSQPPANFEEELKNLNEDVDQSIEIENTEAVWDRPKPSTLNPADDKLVFQQIEIDEYMDFNVMKPVARLYGVTADGNSVVCHVRDFLPYFYFPAPVGFQHSHLPSLKSSLASAVGKANAVESVEIVMKQSIYGYHGDQKSPYIRVTTRDPRDISKCKNKIEEGVIVSGLSRPCQSDTSFESNMQYVLRFMIDCKVLGANWIELPAGEWSFVDKKMSLAQYEVSVRFDKFISHAPEGEWSDIAPLRVLSFDIECAGRKGVFPEPNMDPVIQIASVVQIQGQKKPFIRNVFTLKSCAPIAGSQVLSFEDEKELLQRWSDFFRQVDPDVVIGYNTTNFDFPYLLDRAKHLGVNRFPFLGRIQGLQTEAKDTKFSSKAYGTRENKAINLDGRLQLDMLQAIQRDYKLRSYTLNSVSAEFLNEQKEDVHHSIITELQNGNEETRRRLAVYCLKDAFLPLRLMDKLMLLFNYIEMARVTGIPFNYILVRGQQIKVVSQLYRRALEKDLVIPVLKSSTMEEPYEGATVIEPERGYYDVPIATLDFTSLYPSIMQAHNLCYTTLLLPETVQKLGLVKDVDYEITPNNDMFVKSNRRKGVLPEILSDLLAARKRAKNDLKKETDPFKRAVLDGRQLALKISANSVYGFTGATVGKLPCLQISSSVTAYGRAMIFKTKETVESHFTIKNGYKHDAKVIYGDTDSVMIKFGVDNLKEAMALGREGAALVTKEFLRPINLDFEKVYFPYLLINKKRYAGLYWTREDKYDKLDAKGIETVRRDNCRLVQNVVSKCLDKMLIERDVEGAQAFVKQTIADLLQNKVDLSQLVITKALSKADYTNKQPHVELAERMKKRDAGSAPALGDRVAYVIIKASNNTPAYERSEDPLYVLDNNIPIDTKYYLENQLSKPLLRIFEPILGDKTESLLSGAHTRVVNISTPTVGGLMRFAVKSATCLGCKSPLPKGDSSAACKHCRDRLPELFSHQLEQANSLSIKFSRLWTQCQRCQQSLHQDVICSNNDCPIFYMRKKAQKDMNEAHEKLSRFDYEW</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MZU2</accession>
    <name>A0A1C7MZU2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_09649</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000900">
        <property type="protein sequence ID" value="OBZ82302.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MZU2"/>
    <dbReference type="InParanoid" id="A0A1C7MZU2"/>
    <dbReference type="OrthoDB" id="2288257at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008889384" evidence="2">
        <location>
            <begin position="22"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="67"/>
            <end position="84"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ82302.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="85" mass="8575" checksum="8446B53244CD4BA8" modified="2016-11-30" version="1">MNSKTFLTLLAVVCIIAVVSAQSSTNPVESLQNKASSLAASATQTAPSNPTNQSAGLSLSSGLPSTMFMQALILLGAFFASALLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MZY1</accession>
    <name>A0A1C7MZY1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Bystin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">bysl</name>
        <name evidence="3" type="ORF">A0J61_09532</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the bystin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000871">
        <property type="protein sequence ID" value="OBZ82420.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MZY1"/>
    <dbReference type="FunCoup" id="A0A1C7MZY1">
        <property type="interactions" value="310"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7MZY1"/>
    <dbReference type="InParanoid" id="A0A1C7MZY1"/>
    <dbReference type="OrthoDB" id="2192561at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030686">
        <property type="term" value="C:90S preribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030688">
        <property type="term" value="C:preribosome, small subunit precursor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032040">
        <property type="term" value="C:small-subunit processome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030515">
        <property type="term" value="F:snoRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000447">
        <property type="term" value="P:endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016973">
        <property type="term" value="P:poly(A)+ mRNA export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007955">
        <property type="entry name" value="Bystin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12821">
        <property type="entry name" value="BYSTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12821:SF0">
        <property type="entry name" value="BYSTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05291">
        <property type="entry name" value="Bystin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="70"/>
            <end position="99"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007114"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ82420.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="436" mass="50298" checksum="510148F1DB030C3C" modified="2016-11-30" version="1">MGKDTTKGKAARAQRHDPLHVQLADMPENTLMKKAPRQKFVERNNRAEEAGEEYLDAKLSKKILKIAREQQEQIEKQEADEEERETTVDKNKFPLGFDPDEEEIDEVDQYGDYEELEIDAADADVLEKFLPSAPKQKKTLADLIMDKINEKNAAEGREAIEAEDELSPHMNPKVVEVYTKVGQLLSRYKSGKLPKAFKIIPSLNNWEEILYLTNPEEWTPHATYEATRMFVSNLKARQVQRFLSLVLLDRVRDDIQDNKKLSYHLYLALKKALYKPAAFFKGILFPLCESGNCTLKEAAILGSVLSKISIPVLHSSAAILRLSEMDYTGPNSLFIRILLDKKYALPFKVVDALVMHFARFMNDEREMPVLWHQSMLVFVQRYKQDLVSEQKDILLEVVKKKYHPGITPEVRREIVHSEARDAMLTERDDDDIMMMD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N056</accession>
    <name>A0A1C7N056_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">26S proteasome complex subunit SEM1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">Shfm1</name>
        <name evidence="4" type="ORF">A0J61_09452</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the DSS1/SEM1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000853">
        <property type="protein sequence ID" value="OBZ82500.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N056"/>
    <dbReference type="FunCoup" id="A0A1C7N056">
        <property type="interactions" value="72"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N056"/>
    <dbReference type="InParanoid" id="A0A1C7N056"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008541">
        <property type="term" value="C:proteasome regulatory particle, lid subcomplex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000724">
        <property type="term" value="P:double-strand break repair via homologous recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006406">
        <property type="term" value="P:mRNA export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043248">
        <property type="term" value="P:proteasome assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007834">
        <property type="entry name" value="DSS1_SEM1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16771">
        <property type="entry name" value="26 PROTEASOME COMPLEX SUBUNIT DSS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16771:SF0">
        <property type="entry name" value="26S PROTEASOME COMPLEX SUBUNIT SEM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05160">
        <property type="entry name" value="DSS1_SEM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01385">
        <property type="entry name" value="DSS1_SEM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="2 4" id="KW-0647">Proteasome</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="28"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="57"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="67"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="79"/>
            <end position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00034491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU369057"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OBZ82500.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="88" mass="10367" checksum="C00903CC9F8FEAB1" modified="2016-11-30" version="1">MSAQPQQTQQQKTTEDNSKKNLAQLGALEEDDEFEEFAAEDWGENEEDQNDAHFWEDNWDDDDVEDDFSKQLRAELQKESNQPQPMKM</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N0M0</accession>
    <name>A0A1C7N0M0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_09301</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the glycosyltransferase 32 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000819">
        <property type="protein sequence ID" value="OBZ82650.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N0M0"/>
    <dbReference type="STRING" id="101091.A0A1C7N0M0"/>
    <dbReference type="InParanoid" id="A0A1C7N0M0"/>
    <dbReference type="OrthoDB" id="409543at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007577">
        <property type="entry name" value="GlycoTrfase_DXD_sugar-bd_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46830:SF2">
        <property type="entry name" value="ALPHA-1,4-N-ACETYLGLUCOSAMINYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46830">
        <property type="entry name" value="TRANSFERASE, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04488">
        <property type="entry name" value="Gly_transf_sug"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ82650.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="610" mass="70365" checksum="17E8787E0A3D6AF5" modified="2016-11-30" version="1">MFPTKNNRPFYTNKSSRKRQKWLWRMALVSLLCLLYIVSRTFSTSSTSPSAFRIRPSHTHRLEVQLEAPSRSEQFKELAIAKQTKLVPVGTSIPKIVHFVYGMRDPNPTLDLIHYLSIKSAHDRVKPDKIMFHYHHKPVGDYFERALPMLTLNQVDMVETIFDRPVSHYAHRADVVRLQVLQEYGGIYFDLDVISLKSLDHLLNREFIMAQEGISRSNRINYNYITYLESLDGAVGLCNAMIMARPHSRFLQRWYATYASFDYNDWNYHSVILPGKLAPHFSKEITVLNHTSYFWPLWDSHGLRTLFLEKSYDFSANLGTHIWESAANKNLMRDLDEQVIMEIDNSLYCQLRPFLLDGKPDPRPGSCRILSHSEREDGLIGHWPLSNSDSTINPLPAHDISGHQLTGLIRNGRYTEHGVSLSGDTSYIFLTMPIETAIQPLTVGWWMKTTTQLDGRMVMVVQTDHGRLCITTHAGNQGTVMEIKTIHRDETWTWAPIDSLTIRPTPYLINDDQYHHYMLVVDPMANARGEPALVLYMDRHVVASRFGWQLPKAIGTLVKGIWFGSIEPLNDKYQDPWDNSVSLEAEFRDIQVWERSLNVTEALKQMSLTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-06-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N0M3</accession>
    <name>A0A1C7N0M3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_09368</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000834">
        <property type="protein sequence ID" value="OBZ82581.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N0M3"/>
    <dbReference type="InParanoid" id="A0A1C7N0M3"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ82581.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="25" mass="2917" checksum="7479EAB6D332C670" modified="2016-11-30" version="1" fragment="single">LDKQCNSFLDNFDGLTQFCENLVRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N0V6</accession>
    <name>A0A1C7N0V6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Transcription factor tau subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">TFC7_0</name>
        <name evidence="1" type="ORF">A0J61_09247</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000807">
        <property type="protein sequence ID" value="OBZ82702.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N0V6"/>
    <dbReference type="STRING" id="101091.A0A1C7N0V6"/>
    <dbReference type="InParanoid" id="A0A1C7N0V6"/>
    <dbReference type="OrthoDB" id="433124at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd07067">
        <property type="entry name" value="HP_PGM_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1240">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013078">
        <property type="entry name" value="His_Pase_superF_clade-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029033">
        <property type="entry name" value="His_PPase_superfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051710">
        <property type="entry name" value="Phosphatase_SH3-domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16469">
        <property type="entry name" value="UBIQUITIN-ASSOCIATED AND SH3 DOMAIN-CONTAINING BA-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16469:SF27">
        <property type="entry name" value="UBIQUITIN-ASSOCIATED AND SH3 DOMAIN-CONTAINING BA-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00300">
        <property type="entry name" value="His_Phos_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00855">
        <property type="entry name" value="PGAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53254">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ82702.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="265" mass="30478" checksum="1E28F71024C712D9" modified="2016-11-30" version="1">MPISSVFIIRHAERLDHIDKQWQPDLSLGISDPPITAHGQHQAIETGHALHDLILQQNPESPQIIIYTSPFQRCIDTSIGLAQQLPWHVTLRLEIGLSEWLSEEFFESVCPAAHLISHHQERLARQQTLAYSMRAKNQASYFPSHLHIDYGHQSVYREFEYPEDYKDMIERFERTRLACLKQADDQNKAVVIFVTHAVGANALLDGFRNRVTIPLKSNYCSLSCVRPSMPHSVNSSDQSEDEFDDLRIRPAWKIELTMSDTHLTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N1D7</accession>
    <name>A0A1C7N1D7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Cytochrome oxidase assembly factor 4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">COA4</name>
        <name evidence="3" type="ORF">A0J61_09051</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000762">
        <property type="protein sequence ID" value="OBZ82900.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N1D7"/>
    <dbReference type="FunCoup" id="A0A1C7N1D7">
        <property type="interactions" value="21"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N1D7"/>
    <dbReference type="InParanoid" id="A0A1C7N1D7"/>
    <dbReference type="OrthoDB" id="5586401at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005758">
        <property type="term" value="C:mitochondrial intermembrane space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033617">
        <property type="term" value="P:mitochondrial respiratory chain complex IV assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010625">
        <property type="entry name" value="CHCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039870">
        <property type="entry name" value="Coa4-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13639">
        <property type="entry name" value="CYTOCHROME C OXIDASE ASSEMBLY FACTOR 4 HOMOLOG, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13639:SF2">
        <property type="entry name" value="CYTOCHROME C OXIDASE ASSEMBLY FACTOR 4 HOMOLOG, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06747">
        <property type="entry name" value="CHCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51808">
        <property type="entry name" value="CHCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CHCH" evidence="2">
        <location>
            <begin position="25"/>
            <end position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF06747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ82900.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="77" mass="9093" checksum="F0A70534C7BD3AA8" modified="2016-11-30" version="1">MSENHITKQEEEEDPYNARIEKTGCYKENEALQLCFYDKRDWRLCQEEMKAFRACFTKNSKNAGSQELLASSKHIDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N1Y2</accession>
    <name>A0A1C7N1Y2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_09264</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000811">
        <property type="protein sequence ID" value="OBZ82686.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="InParanoid" id="A0A1C7N1Y2"/>
    <dbReference type="OrthoDB" id="2250192at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.60">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11915">
        <property type="entry name" value="SPECTRIN/FILAMIN RELATED CYTOSKELETAL PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="251"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1494"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ82686.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="1494" mass="171690" checksum="EF9715BF1AF645BE" modified="2016-11-30" version="1" fragment="single">MTTLEKHSREENILNWISQCSSTTITEAHQLTDLALLGTVIEALFNTRIDRQQEHIQDVINQIPNTGQSQFIYNNDDDLPALLDYIQTAYELHFVTYTILNNTQLTFTSFFHEFIPTTNQQEKIDIRNYLLSWASFILADYINASILPPILDLPTMSSNGIYLLSLLHYHQPALIPDLHLYLHEPQALDIAIKLTWEIYHIPSSFFTQDTAYIYLLQLVASLQVPNSEQTVQRHKDIERFKNLIKITNDASTTPTPILTDNMDCPPPPPSNDNGNNNNDSEEQGDEKRNSTTFTSTYTVQQLKITKTTVTKYSDGTEVPSELEEFETRASTLTEKMNGLQHRLAMIIPTRATATSPSSVNSDSMMDLFSTDDNTTATSLRDSSSHYSLASNEDLTQLSLPQQQLIRVLHPLQAAEEDYAAYDRNFKALQSEFQTLTDGDFNLLLHVYLVEQLEPAWQEHPKVIWRKQQLSQLHHSLSSEFERSELTLSSFRRGFAFARMCQSIRHELELVQNKMVKSISTHNDIQDLEFRVEKTSDMIDTLKANFSDLLLLADSNTSEEGSMMIATSESPSVTQNTSHDTAYLAKYETVENKNKLVKSWVEEVRIWFSEAERIRQWMEIRMNQLDQIVIPSSLLPPEESPVTREELQSLNSQHAILEKEIETFNRQDMERLRSHVKTLTGTDRQDNSKDLSPADTTTIGITLTTLNMLDKMMSSLRKKSLDLVVLTKRLEWEENYVKSMVWLKNTDEETDKFLHEAARWRPSELNQEGDDIAHMNDYSRREWLLNREKQKSLVTEQLYRLERERVAFDKDQFTKTVNAFLDLSNQGMELPDQFETRQSACEQQFEDLIKRIGFARQVVEQRLSVMDFLYQTEIAMEEGRILSAEITEAENKVRPTDTDQEMSSRVDTMEKKLAHLLTVTSRAVVFPVPALDEDKEDNEADNQEINRVITEKCNQLLSLRDALYERLNSYRFVLQLYRQAKHCLEDADRLCEWADERMKTIRRAKAEMQEGLGTIFTAEDLQRLERDRANVQNKLENDKEKQVVDLVLDIQTLLDTSKSLDIPSFDRDSLVEVSEHLQERFDCLQTLLKEHVTDLEAMRKKMEDGNTYFENARSLRSFINETRHSMPGLKQTCGFMTGQSEEQDKRRFEMLNQALAKINQSYKEQESQFHQLCSHYALMEPTRIENIDEIRAMQTNLQQDWNQLSNEVRDMNQFTEVVGEWYNRQRRLSMVENSLMAGLNDEITHLARSGWKSEADLAGVHAKISQASAVLDEIGQAIRAADNKEDPLQTANYSCARDRLSQLTNQVLTASKNLQALKSDANKAVALGTFLSEADKVLSEIQRQKELVMRRMSTVGNSGFASQDKASIDAMFKSIQSATVYSEKGAQSFAKQLSALNQKAAELAKEGYDAGSLQDPIKRIHENLNQLSNTIGIEKKQAMFVQKVFLHAKAVNDLKQWMDHCTHAIQQLPTDVCMNDEQELQAQLDTIKKNMADAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N1Z6</accession>
    <name>A0A1C7N1Z6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Uncharacterized protein C24H6.11c</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">A0J61_08786</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000711">
        <property type="protein sequence ID" value="OBZ83165.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N1Z6"/>
    <dbReference type="FunCoup" id="A0A1C7N1Z6">
        <property type="interactions" value="11"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N1Z6"/>
    <dbReference type="InParanoid" id="A0A1C7N1Z6"/>
    <dbReference type="OrthoDB" id="409725at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000329">
        <property type="term" value="C:fungal-type vacuole membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034618">
        <property type="term" value="F:arginine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015174">
        <property type="term" value="F:basic amino acid transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034490">
        <property type="term" value="P:basic amino acid transmembrane import into vacuole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd00038">
        <property type="entry name" value="CAP_ED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd07042">
        <property type="entry name" value="STAS_SulP_like_sulfate_transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="entry name" value="Jelly Rolls"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.750.24">
        <property type="entry name" value="STAS domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000595">
        <property type="entry name" value="cNMP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018490">
        <property type="entry name" value="cNMP-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052706">
        <property type="entry name" value="Membrane-Transporter-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011547">
        <property type="entry name" value="SLC26A/SulP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002645">
        <property type="entry name" value="STAS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036513">
        <property type="entry name" value="STAS_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43310:SF4">
        <property type="entry name" value="AFR304WP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43310">
        <property type="entry name" value="SULFATE TRANSPORTER YBAR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00027">
        <property type="entry name" value="cNMP_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01740">
        <property type="entry name" value="STAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00916">
        <property type="entry name" value="Sulfate_transp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00100">
        <property type="entry name" value="cNMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51206">
        <property type="entry name" value="cAMP-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52091">
        <property type="entry name" value="SpoIIaa-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50042">
        <property type="entry name" value="CNMP_BINDING_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50801">
        <property type="entry name" value="STAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="219"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="260"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="285"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="311"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="349"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="387"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="418"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="477"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="560"/>
            <end position="591"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="611"/>
            <end position="643"/>
        </location>
    </feature>
    <feature type="domain" description="STAS" evidence="8">
        <location>
            <begin position="684"/>
            <end position="797"/>
        </location>
    </feature>
    <feature type="domain" description="Cyclic nucleotide-binding" evidence="7">
        <location>
            <begin position="896"/>
            <end position="983"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="73"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="129"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="75"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="146"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="156"/>
            <end position="176"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OBZ83165.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="1017" mass="114533" checksum="C3378AA5957FF88F" modified="2016-11-30" version="1">MDRINSSTSSNVDYSSFSSPKEINIKGKLDEEIPSRSYYSSHIHIEEPVDEDARYSASVESIRAHSLALGDRYMQESSPANSPPTNLQSDDKFLKPVSPLSLGNNSHSILSSLLQKDNLKRNQDDFAQDETDERQHLLSPSSSAPSRKKLHHKKSSNNYFSISDSDPELGNQTQEGSIEDQQESTRKQEQSYSYYRRITWKQLRDPQTWIKCFTQPLRYIPAVILGLLLNLLDAISYGMITFPLNNPMFASFGPDGISMFFVSCIVSQLVYSCGGSAFDGGNGSMMIEVVPFLHIIAERIVSVVGSDRPDVAIPSTVVAFAMSSIMTGLAFFLLGALKLGKLIGFFPRHILVGTIGGVGWFLVATGIEVSGRLDEDLEYTIPMFKKVFLESHTFMLWFSAFAVAILLRLIQHRITSPLVVPVFFMVLPLAFYLIVLVLGLDVSQVRNDGWIFPLVESNTPFWHFYTYFNLKMVDWRAVVETIPAMLALTFFGVLHVPINVPALGVSTNKDDVDVNRELVAHGISNAASGLLGSVQNYLVYTNSLLFIRSGGDSRVAGVMLAGATTVLWMVGPWIVGYIPVMVVGSLIFHLGLDLLKEALVDTWKSVHYLEYITICTIIASMAIMGFVEGIFVGIVLACIFFVVQNARGNKAIRAIYTGQYMRSTVRRLYRQEQFLNQVGGQIQVVKLQGYLFFGTIDQVETAIRDMLDEHAWDKHPIRFLILDLQLVQGLDFSAAEAFVRIRRLLRARQVYMIVCNVARHSDEEKALMKAGIWTHHQQHDEDDLKCFEHINEAVEWCENVLLTSFFENKPKHILSGTPSTMVPVSNKHYGYEDRLASAGSPRHNIISNAIHQVFSESHGPVVHKNTSQPTLILVQTFGEIKQGKTSIEFFHKLSKYFERVTAKKNDTLYHEGDPCEYLLILEQGSLRSLMHVLKDEVTVETILPGTVVGELGMFSHNPVRTRSLMAETDSVFWILSRESFDRMCTEVPDLANEFIFLCLYFSSERLDTMTRYAFHLH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N336</accession>
    <name>A0A1C7N336_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">MGAT3</name>
        <name evidence="1" type="ORF">A0J61_08417</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000645">
        <property type="protein sequence ID" value="OBZ83533.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N336"/>
    <dbReference type="STRING" id="101091.A0A1C7N336"/>
    <dbReference type="InParanoid" id="A0A1C7N336"/>
    <dbReference type="OrthoDB" id="6474464at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003830">
        <property type="term" value="F:beta-1,4-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006044">
        <property type="term" value="P:N-acetylglucosamine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006813">
        <property type="entry name" value="Glyco_trans_17"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12224:SF0">
        <property type="entry name" value="BETA-1,4-MANNOSYL-GLYCOPROTEIN 4-BETA-N-ACETYLGLUCOSAMINYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12224">
        <property type="entry name" value="BETA-1,4-MANNOSYL-GLYCOPROTEIN BETA-1,4-N-ACETYLGLUCOSAMINYL-TRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04724">
        <property type="entry name" value="Glyco_transf_17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ83533.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="341" mass="39595" checksum="E3BFA48D231129F5" modified="2016-11-30" version="1">MLLQPTLFTDLGYYTRPIWDKNPNKFEIIPHYYSEDVPLKDLCKLHGWELKDETEITKSKVYDAIIFSVELDLLEIRIRELWDVVDTFVILESNATFTGETKSYTFEQHKKQFAFAASKIHHTMIQQTELPTGESPFYNEIGMRRAMNQALSDAGVKQGDLVVMSDVDELIRGKSLLLLKSCRGIPDRMHLQLKNYIYSFEFPLDMQSWRAHIVRFDTTETFYSHGQISDYLLADAGWHCSFCFRTIKEFQFKMKSYSHSDRIRHEGILAPNRIQQTICDGKDIFDMPPESYTYKDMVSKLGAIEPIASAVGLPASVLRNAERYYFLLPGGCIREDYEQIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N3Q0</accession>
    <name>A0A1C7N3Q0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_08682</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000692">
        <property type="protein sequence ID" value="OBZ83269.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="InParanoid" id="A0A1C7N3Q0"/>
    <dbReference type="OrthoDB" id="2268828at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ83269.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="206" mass="24288" checksum="F39A7C729AEFE03B" modified="2016-11-30" version="1">MQRLVVEENHSVADVDTGRFGNNMGSNYQVAPKNNTNTLVQRYQQRIDLLFETTLECNDIDELXKLNIMIEQYEKLRDRLLNKNNNSEKKSDSTSPMIKNQINKNEIPIFQFMDDPAVTKTDNRTAHANAEGFISAFELTMKINEIDIDVDWKKYLTTSFLHSKNNKHMRWYQNHIDVLEDHVRWDQVRQAIIDRFGDINDTKKIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N3W5</accession>
    <name>A0A1C7N3W5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">BTB/POZ domain-containing protein KCTD14</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">KCTD14</name>
        <name evidence="2" type="ORF">A0J61_08602</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000679">
        <property type="protein sequence ID" value="OBZ83346.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N3W5"/>
    <dbReference type="STRING" id="101091.A0A1C7N3W5"/>
    <dbReference type="InParanoid" id="A0A1C7N3W5"/>
    <dbReference type="OrthoDB" id="2414723at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051260">
        <property type="term" value="P:protein homooligomerization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045068">
        <property type="entry name" value="BACURD1-3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000210">
        <property type="entry name" value="BTB/POZ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003131">
        <property type="entry name" value="T1-type_BTB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11145">
        <property type="entry name" value="BTB/POZ DOMAIN-CONTAINING ADAPTER FOR CUL3-MEDIATED RHOA DEGRADATION PROTEIN FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11145:SF8">
        <property type="entry name" value="RE57120P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02214">
        <property type="entry name" value="BTB_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00225">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54695">
        <property type="entry name" value="POZ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BTB" evidence="1">
        <location>
            <begin position="147"/>
            <end position="250"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ83346.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="360" mass="41832" checksum="A85E153C2818825E" modified="2016-11-30" version="1">MQDTNIDPIAFFDHLAATSPSSKNGSSFFSKSDDSQANYSIETVKQQNPPIQHAQSIHFQQVWNNLVDEHTAEQQALSRHLKSQLNALEEVDDHFRKANIDLHLKIENTYYELSSDIHHHKQQLEGEKTQFEVEKKLIKEIHQFRDEKIKLNVGGQLFETSLSTLRKDPNSMLANMFGENSKIMPDADNSYFIDRDSTYFRLVLNYLRDLQIPTGIINDHKVMDELMQEARFYKLYDLLRLKWSHIPRMTQDELHRLYPPPKPFSSQNHTAYRPIVIQLEKKNLANLDFSGYHIDPRSNFSESNLENCHFEHAKFGFDFDHQVDFSYSFLLGACLPPEGTENRASGVQFNLEGAILDNLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N3Y4</accession>
    <name>A0A1C7N3Y4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">GTPase-activating protein GYP7</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">GAP for YPT7</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">GYP7</name>
        <name evidence="6" type="ORF">A0J61_08139</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000600">
        <property type="protein sequence ID" value="OBZ83813.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N3Y4"/>
    <dbReference type="FunCoup" id="A0A1C7N3Y4">
        <property type="interactions" value="293"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N3Y4"/>
    <dbReference type="InParanoid" id="A0A1C7N3Y4"/>
    <dbReference type="OrthoDB" id="10264062at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.472.80:FF:000005">
        <property type="entry name" value="TBC1 domain family member 15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.270">
        <property type="entry name" value="putative rabgap domain of human tbc1 domain family member 14 like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.80">
        <property type="entry name" value="Ypt/Rab-GAP domain of gyp1p, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000195">
        <property type="entry name" value="Rab-GAP-TBC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035969">
        <property type="entry name" value="Rab-GAP_TBC_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021935">
        <property type="entry name" value="SGSM1/2_RBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22957:SF502">
        <property type="entry name" value="SMALL G PROTEIN SIGNALING MODULATOR 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22957">
        <property type="entry name" value="TBC1 DOMAIN FAMILY MEMBER GTPASE-ACTIVATING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12068">
        <property type="entry name" value="PH_RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00566">
        <property type="entry name" value="RabGAP-TBC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00164">
        <property type="entry name" value="TBC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47923">
        <property type="entry name" value="Ypt/Rab-GAP domain of gyp1p"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50086">
        <property type="entry name" value="TBC_RABGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0343">GTPase activation</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rab-GAP TBC" evidence="5">
        <location>
            <begin position="341"/>
            <end position="562"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="610"/>
            <end position="637"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022468"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00072091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00082648"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OBZ83813.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="652" mass="75506" checksum="96A637CE8BC3A7F6" modified="2016-11-30" version="1">MDESFDMLLDPRVKKTAEGSVKLIYSKSKVYVHPSSHSADFIAGYLSLVENSEKIYLVAWAPETKDSMEDNMPDSPYALSAPISTIHSIVINPPSLSKWYGNIVINFKQGPSAGPYWFHDDESQSTVLQKNNQGGKLTATSSLHWGGDEFITHLSQLVPIHKSNDHEYLVNQLNPLASLSLTSTQMDPLVATLKEARWHILEKLSRVTKFSKETAVHLLNRPTSHPESLCHQSEAVQTTIDDYDSARIFLAKWAAGLAAQSAKAVPNDQKYRHVGIWGHDEGQEETALGVFEILNSESDQSIPTHTRTSPVTEADWRGYFDQQGQLIVPEIMVKKHIFSGGLDHSVRKEAWLFLTGVYPWQSTRQERQQIARDKRASYDAYKATWSQDHVYRQQDSWQDQKHRIDKDVHRTDRTVDIYMTEDLPNPDPAMHVGTNLHLETLKAILCTYNVYHPELGYVQGMSDLLSPLYAVIEDEALSFWAFVGFMDRMQQSNFYTDQSGMHQQLLKMDRLLHWMDPSLYQHLQKTDSGNFFFCFRWLLVWYKREFAWKDMMTLWEVLWTDYLTDQFHLFIALAILDQHRDVMMDYLKTFDEILKYINDLSMTIPLQETLQRAEILYRQFQQRVEAVDHKRAQLEETSRDSLPVIHPLLREI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N421</accession>
    <name>A0A1C7N421_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_08161</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000604">
        <property type="protein sequence ID" value="OBZ83787.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N421"/>
    <dbReference type="InParanoid" id="A0A1C7N421"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="204"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="204"/>
            <end position="233"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ83787.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="480" mass="54442" checksum="5CD57D802915322D" modified="2016-11-30" version="1">MTTSLDSETKKLITYLQTSSPTFSLLKFYEKNKDLFINEPDLRKRWRTRWSKAVLSVGVSDTDLDDSEPSWRELSKQQSKDKMSLFTKTLSLKTNAVLCTDYGVEDAEVGVWVLGGVDFAQLFCASRREVVTLVSQGEYIKEDQYLLLSFVVRVPRQFSDFVLGGDPKGLKLLLKKYSSIRAFAFSREVALMFFELSLLAQQKEEDEDKEEDEDKDKDKDKEEDEDEDEDEDEEKKTKEDVLYEMAKLARKKKNGEVKALMLISQDFLEKKWSSLCGSEESFIDQHLLLFIEKVLGQCEEFDCVRSSGRISLSENSYSNSNNKDVCLAMKPDFIFSCGDVGFFAVEVKPPGVRSSQVLTDQSKLGLELKRMLDQQILQGSAEPKSFGLLVEGLKCTFFSCCIEARGVYLLVEELSFSLPSGAADFSMVLGVTQHFVSLRNAMLESATSLLKKRRTEEGVASLRALIKPTVELPQKRKLSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-06-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N437</accession>
    <name>A0A1C7N437_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_08524</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000665">
        <property type="protein sequence ID" value="OBZ83426.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N437"/>
    <dbReference type="InParanoid" id="A0A1C7N437"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ83426.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="228" mass="26750" checksum="F584C22BBB4BA1D8" modified="2016-11-30" version="1">MIQFPWDDDDSFSLCLDRFPNIPLDHLETRMASTEWDLSSAEEMALPGVDEERLEEPWIRSGSYLSDSTLSLEEIFPANDTLRARYLQQIHATFPYNNNNLHDLPYRHPTSTYGSTTPSSTLEPNKRTFHSPKPCILTLLFNRIRPMNKRRQEGYHQKPLPALPPMLPPHQTMNEPIVVTKESYMFITSYDDSIDPTMMPVGQKKKKKRTSMDSIWRYMDYFKRPFSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N4D4</accession>
    <name>A0A1C7N4D4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_07969</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000573">
        <property type="protein sequence ID" value="OBZ83982.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N4D4"/>
    <dbReference type="InParanoid" id="A0A1C7N4D4"/>
    <dbReference type="OrthoDB" id="2286319at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="111"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="118"/>
            <end position="127"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ83982.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="185" mass="21369" checksum="045839E4F8AAE8D4" modified="2016-11-30" version="1">MNVIDQQTSFQYDINKEILMKRLADASQYKIYPSIIPKNELPLRKILLTTRLWNHVRRQQALMTIPSSANGWLFQQQDNTIILEPEIKEQEDIPKNQYDWSWFDKEEKSSLSHEDTSSQDTSSFHNTTSKKRVLDQEDENEDKEQVQIKKIKLHFNTIDSPATPAGPDAVETTATTTHPAVLLSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N4N2</accession>
    <name>A0A1C7N4N2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">60S ribosomal protein L16</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">crp-46_1</name>
        <name evidence="5" type="ORF">A0J61_07868</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the universal ribosomal protein uL13 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000558">
        <property type="protein sequence ID" value="OBZ84082.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N4N2"/>
    <dbReference type="STRING" id="101091.A0A1C7N4N2"/>
    <dbReference type="InParanoid" id="A0A1C7N4N2"/>
    <dbReference type="OrthoDB" id="1882297at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022625">
        <property type="term" value="C:cytosolic large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017148">
        <property type="term" value="P:negative regulation of translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="6.10.250.3250:FF:000001">
        <property type="entry name" value="60S ribosomal protein L13a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.3250">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1180.10">
        <property type="entry name" value="Ribosomal protein L13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005822">
        <property type="entry name" value="Ribosomal_uL13"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023563">
        <property type="entry name" value="Ribosomal_uL13_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036899">
        <property type="entry name" value="Ribosomal_uL13_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11545:SF3">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN UL13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11545">
        <property type="entry name" value="RIBOSOMAL PROTEIN L13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00572">
        <property type="entry name" value="Ribosomal_L13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52161">
        <property type="entry name" value="Ribosomal protein L13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00783">
        <property type="entry name" value="RIBOSOMAL_L13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 5" id="KW-0689">Ribosomal protein</keyword>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006227"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003877"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OBZ84082.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="132" mass="14862" checksum="4BA2E32D983376A4" modified="2016-11-30" version="1" fragment="single">PFHFRAPSRILYKAIRGMIPHKTSRGAAALDRIKLFEGVPAPYDRVKRMVIPDALRVLRLKPGRKYTTIGRISHEVGWKYQDVVAKLEEKRKAKSAAYFQRKTALAAIQKKAVESKADALKDVNTSIAALGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N513</accession>
    <name>A0A1C7N513_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">protein O-GlcNAc transferase</fullName>
            <ecNumber evidence="3">2.4.1.255</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">SEC_1</name>
        <name evidence="10" type="ORF">A0J61_08204</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the glycosyltransferase 41 family. O-GlcNAc transferase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.255" evidence="3"/>
    <dbReference type="EMBL" id="LUGH01000610">
        <property type="protein sequence ID" value="OBZ83746.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N513"/>
    <dbReference type="STRING" id="101091.A0A1C7N513"/>
    <dbReference type="InParanoid" id="A0A1C7N513"/>
    <dbReference type="OrthoDB" id="421121at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097363">
        <property type="term" value="F:protein O-acetylglucosaminyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006493">
        <property type="term" value="P:protein O-linked glycosylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.11380:FF:000004">
        <property type="entry name" value="UDP-N-acetylglucosaminyltransferase (AFU_orthologue AFUA_1G03380)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11380">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2000">
        <property type="entry name" value="Glycogen Phosphorylase B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029489">
        <property type="entry name" value="OGT/SEC/SPY_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44998">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44998:SF1">
        <property type="entry name" value="UDP-N-ACETYLGLUCOSAMINE--PEPTIDE N-ACETYLGLUCOSAMINYLTRANSFERASE 110 KDA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13844">
        <property type="entry name" value="Glyco_transf_41"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13374">
        <property type="entry name" value="TPR_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13181">
        <property type="entry name" value="TPR_8"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50293">
        <property type="entry name" value="TPR_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 10" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0677">Repeat</keyword>
    <keyword evidence="7 8" id="KW-0802">TPR repeat</keyword>
    <keyword evidence="5 10" id="KW-0808">Transferase</keyword>
    <feature type="repeat" description="TPR" evidence="8">
        <location>
            <begin position="178"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="8">
        <location>
            <begin position="466"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="8">
        <location>
            <begin position="500"/>
            <end position="533"/>
        </location>
    </feature>
    <feature type="domain" description="O-GlcNAc transferase C-terminal" evidence="9">
        <location>
            <begin position="698"/>
            <end position="886"/>
        </location>
    </feature>
    <feature type="domain" description="O-GlcNAc transferase C-terminal" evidence="9">
        <location>
            <begin position="963"/>
            <end position="1164"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005386"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF13844"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OBZ83746.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="1200" mass="136156" checksum="996A8564790D8AE1" modified="2016-11-30" version="1">MYPLLNDGAIPQTRSLKQPVDFNHVSHDDPAAFAYFQQELSSPLQLTPTTNQHPSIMVPPQSPTLASYYFENGWVNHYYDPKRKYLSSRRTEPSEVKRLHLDNNADEWREHLLQYAHTLYSTSPRNPYLLPLLHSLHDAYPSHLPTLLLLACVYYSYGEYSLSLKYNQLILKYDAHYVEAMSNIGTTLRSMGKTTEAERWWYQAVKLRPAYWDAVENLVGVLCAKTEGETRYQEALAVCDFVESFFFKQPTTPLKAPPQLPVHQLSRLQNLFYAKGNLKYALGDTLGAQREYEKGLELAFGGIDLMSLCRLICYTCHPTSPSTELPLLLLQPDQAARILQLAFPNANGLLPTLVSLTGPDAMAHIQQTNQTTSVLLLTLAKLYQDLLHSANVGAPKPTLAMLLPLYYMSLALHASPSTANNLGIILSSIPATVTMHAVKLTVQPLTGTMLAMQYYMYGLQLDPRHPHLYTNLGSLLKDMGHLNEAVSMYEKAVEFNPKFDVALANLGNAIKDLGRVQESVQWYRRAVEVNPNFVDAVCGLVNSLNGVCDWRGRGGVRQEASVDAYGQFIPPSPDQPPTGWMSHIVDIVNRQLEEGSLWGAGILNVAVHHKTLGESLVERWVAISGDSPVHWRARLADLQTASKKNEGGWLIRMVERIMRRLQYLWYVNRLQQKGHDITPETAIQYARPLIPAHLSLPPVPTVLPFHTFTYPLDARQIRLISHRNALRISHTALTSSWLPAHVYPPPPPPQHRLKIGYISSDFNNHPLSHLMQSVFGMHDRARYTVYCYATTPSDQSPYRLKIEQEAENFIDVSSWSNQQVVERVVSDGIHVLVNLNGYTKGARNEIFAARPCPVQCSFMGFAGTLGGQWCDYIVADPIVCPPEKVSDHVWRHQRGGQLQGGDLPGDLDPEQISDDFAYTEKFIYMPHSYFVNDHKQGFREEENLDWTREEEKRWQMRRELFPQLPDDVVIFANFNQLYKLEPATFRVWLKILERVPNSILWLLRFPPAGEHHLKRCALAWAGPHVAQRVVFTDVAPKHVHIHRGRVADLFLDTPECNAHTTAADILWSGTPILTFPKYIHKMCSRVGASIAMATGLGDAMVVMTEEAYEQRAVELAQSVTYTYLSTPTGMKRQGHGQLMQLRKQLFSTREQSRLFDTARWTRNLERGYAEAWRRWATGEAFEEDKDGCIWVTDPDDHIPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N5A8</accession>
    <name>A0A1C7N5A8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">DUF7593 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">A0J61_07660</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000530">
        <property type="protein sequence ID" value="OBZ84290.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N5A8"/>
    <dbReference type="STRING" id="101091.A0A1C7N5A8"/>
    <dbReference type="InParanoid" id="A0A1C7N5A8"/>
    <dbReference type="OrthoDB" id="194358at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004842">
        <property type="term" value="F:ubiquitin-protein transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0085020">
        <property type="term" value="P:protein K6-linked ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056015">
        <property type="entry name" value="DUF7593"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24171">
        <property type="entry name" value="ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 39-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24171:SF8">
        <property type="entry name" value="BRCA1-ASSOCIATED RING DOMAIN PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00023">
        <property type="entry name" value="Ank"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24513">
        <property type="entry name" value="DUF7593"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01415">
        <property type="entry name" value="ANKYRIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="10"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="9"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="9"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="29"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="62"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="95"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="161"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="194"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="227"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="409"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="442"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="475"/>
            <end position="507"/>
        </location>
    </feature>
    <feature type="domain" description="DUF7593" evidence="5">
        <location>
            <begin position="642"/>
            <end position="755"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="330"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="579"/>
            <end position="618"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="363"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="381"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="394"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="589"/>
            <end position="598"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="4">
        <location>
            <begin position="606"/>
            <end position="618"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF24513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OBZ84290.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="812" mass="91970" checksum="7FD54A8B6092EA99" modified="2016-11-30" version="1">MTNDKTSHQRMNKPKGRSACQDPNKTDKAGRTKIFSYTSSGNLDKVKELVERGADVNHRDNAGWAPLHEAALKGQYEIARYLIQSGANANVRGFEDDTPLHDACSYGYPDCVQLLIDSGADVYALNADKKRPIDLCEDDDCIRIVKNRMKQVDDLAERDQQGRTALHRVCEKGTIEQIEQLLKSGLDSNATDIHSWTPLHIAAEHGRLEAIQALTQAGADINSTNDQGQTALHIACQQGHDAVASYLVDTGVDIHATDNDQQTAYQVAKSVTIRQIITARIDQERKLRATTEAIDEVTFVSNTKQKRKAEDNQLSREERKIQAIMRAFEKAEKKQQAAKTKKTNNDNLVHNKPVNNDKKRKQTRQESRECSVDSQSDQHSHIHHQPNHASKKSNHVDFSKLDPHKKDTSGRTHLHRWSIRGDVQAVKALLDIGANPCEKDNAGYTPLHEAALRGKTDVVRLLLENHADVNSKGADMDTPLHDATENGFPEVVQLLLEYGADVDVKNSKGHTPLDIAIQEENDEIEMLLRDHKNIKPKKRKLNLNHDKFQDYTQLSQTTSPTQPQSPTSPIGTFDVSAKAHARQLSGQHLPKKSLKPHLAKTEAVPPDGPHTPIPTPPPERWHKAIKKEEEDFHSKNEDLYPSLHCASRYLPLYTIQLVNDLNSHFFVVDLQISLLLGITTHQLMNQYPHLHRRQVLSKEKERLWSPLSSMICASHEYLKHDFDSMSAFRESEKQRFLESDIFFVRLDQIVSMIKDDYSHLSESLITINLDIGYTAEYSVPQKKRNMKLPPKFAMKMKKCGMLKFDQQQQNLM</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N5B2</accession>
    <name>A0A1C7N5B2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_08108</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000595">
        <property type="protein sequence ID" value="OBZ83846.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N5B2"/>
    <dbReference type="InParanoid" id="A0A1C7N5B2"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ83846.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="108" mass="12157" checksum="B3F473B9A1A8ED97" modified="2016-11-30" version="1">MIENINLCPVAKMGGLNLSLLRILDLKELSIVKMPDSIILVLYSMRAVAVGNTNGGSNYFMSFQIQGGLHYTRDPLMNESVFDSKYAQLYVDDSLFATQLRRCQNSKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N5N9</accession>
    <name>A0A1C7N5N9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="20">DNA replication ATP-dependent helicase/nuclease</fullName>
            <ecNumber evidence="20">3.1.-.-</ecNumber>
            <ecNumber evidence="20">3.6.4.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="25" type="primary">dna2</name>
        <name evidence="25" type="ORF">A0J61_09286</name>
    </gene>
    <organism evidence="25 26">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="25 26" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="25 26">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="20">Key enzyme involved in DNA replication and DNA repair. Involved in Okazaki fragments processing by cleaving long flaps that escape FEN1: flaps that are longer than 27 nucleotides are coated by replication protein A complex (RPA), leading to recruit DNA2 which cleaves the flap until it is too short to bind RPA and becomes a substrate for FEN1. Also involved in 5'-end resection of DNA during double-strand break (DSB) repair by mediating the cleavage of 5'-ssDNA.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="27">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.12"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="20">Nucleus</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="20">Chromosome</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 20">Belongs to the DNA2/NAM7 helicase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="25">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.-.-" evidence="20"/>
    <dbReference type="EC" id="3.6.4.12" evidence="20"/>
    <dbReference type="EMBL" id="LUGH01000816">
        <property type="protein sequence ID" value="OBZ82664.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N5N9"/>
    <dbReference type="FunCoup" id="A0A1C7N5N9">
        <property type="interactions" value="450"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N5N9"/>
    <dbReference type="InParanoid" id="A0A1C7N5N9"/>
    <dbReference type="OrthoDB" id="6513042at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005694">
        <property type="term" value="C:chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017108">
        <property type="term" value="F:5'-flap endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017116">
        <property type="term" value="F:single-stranded DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033567">
        <property type="term" value="P:DNA replication, Okazaki fragment processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071932">
        <property type="term" value="P:replication fork reversal"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd18041">
        <property type="entry name" value="DEXXQc_DNA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd22318">
        <property type="entry name" value="DNA2_N-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18808">
        <property type="entry name" value="SF1_C_Upf1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000789">
        <property type="entry name" value="DNA replication ATP-dependent helicase/nuclease DNA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:001170">
        <property type="entry name" value="DNA replication helicase Dna2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.320.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022765">
        <property type="entry name" value="Dna2/Cas4_DUF83"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026851">
        <property type="entry name" value="Dna2/JHS1_DEXXQ-box"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045055">
        <property type="entry name" value="DNA2/NAM7-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041679">
        <property type="entry name" value="DNA2/NAM7-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041677">
        <property type="entry name" value="DNA2/NAM7_AAA_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014808">
        <property type="entry name" value="DNA_replication_fac_Dna2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011604">
        <property type="entry name" value="PDDEXK-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047187">
        <property type="entry name" value="SF1_C_Upf1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10887:SF433">
        <property type="entry name" value="DNA REPLICATION ATP-DEPENDENT HELICASE_NUCLEASE DNA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10887">
        <property type="entry name" value="DNA2/NAM7 HELICASE FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13086">
        <property type="entry name" value="AAA_11"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13087">
        <property type="entry name" value="AAA_12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01930">
        <property type="entry name" value="Cas_Cas4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08696">
        <property type="entry name" value="Dna2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 20" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="12 20" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="20" id="KW-0158">Chromosome</keyword>
    <keyword evidence="9 20" id="KW-0227">DNA damage</keyword>
    <keyword evidence="16 20" id="KW-0234">DNA repair</keyword>
    <keyword evidence="4 20" id="KW-0235">DNA replication</keyword>
    <keyword evidence="15 20" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="8" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="11 20 25" id="KW-0347">Helicase</keyword>
    <keyword evidence="10 20" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="13 20" id="KW-0408">Iron</keyword>
    <keyword evidence="14 20" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="6 20" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="18 20" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="5 20" id="KW-0540">Nuclease</keyword>
    <keyword evidence="7 20" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="17 20" id="KW-0539">Nucleus</keyword>
    <keyword evidence="26" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA replication factor Dna2 N-terminal" evidence="22">
        <location>
            <begin position="134"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="domain" description="DUF83" evidence="21">
        <location>
            <begin position="348"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="domain" description="DNA2/NAM7 helicase helicase" evidence="23">
        <location>
            <begin position="688"/>
            <end position="772"/>
        </location>
    </feature>
    <feature type="domain" description="DNA2/NAM7 helicase helicase" evidence="23">
        <location>
            <begin position="788"/>
            <end position="855"/>
        </location>
    </feature>
    <feature type="domain" description="DNA2/NAM7 helicase-like C-terminal" evidence="24">
        <location>
            <begin position="864"/>
            <end position="1078"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00047995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="RuleBase" id="RU367041"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="21">
        <source>
            <dbReference type="Pfam" id="PF01930"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="22">
        <source>
            <dbReference type="Pfam" id="PF08696"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="23">
        <source>
            <dbReference type="Pfam" id="PF13086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="24">
        <source>
            <dbReference type="Pfam" id="PF13087"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="25">
        <source>
            <dbReference type="EMBL" id="OBZ82664.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="26">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="1154" mass="130470" checksum="AE7A3975C6BDE973" modified="2016-11-30" version="1">MSSIRMEASTATTEQLEVQINKRIKTDHQSTQSDDDLFDDDLDIQEIDLSAIMASRKPANQNLSVSFEHAPVEGLGDLLNTTESSPKPPINSQSKRKKFTRYLVANVRYSAYEIRESQFTEKVLTLVQEEANCAVTARLRQEWEHTTVAIGDVVHVPYTDTMENDIVIDNHQNFIVVHPDKLISCTAVADSFACIRKSVLQMKIRGASEYSEALVHGNIIHAVLQEALITRDFSLKSIRKNISNTIKNSVEALYAIDQDEQTASTILTTYADSIHQFGMLYVNDHPKPNAKVSKDMGANVEKELGCTSVAICKILDIEEHLWSPTFGLKGMIDASVQLKLSPSNKVLTIPFELKTGKTSRFLTNRAQTLLYTLLMSDRYDIDVRAGVLYYSKTNSLYLVSALQNDLQSLVMARNHLAVAERKSSIPPMIKDMHTCQYCYLNHACTIYHKSIELGTSKTSELHDLFDKMTGHLNDSTTEFVRHWWNLLDQEETDIDYVRKDIWSQPAEIREMMGQCLSNMKLDVNASQIDSQASRWRYCFVRTPQQPLVCNISVGDPVVVSSMEGHINLAMGFVTKISLSDIHLTLNEPLRIPPQMDLGFDAEHNQNFYSFVGVQDNLAEFYNRSKVLYRIDKDEMSTGMSLLRNNLIMLVARTNKDDCSGERLRELIIGMKKPEFSTAAPHISATSKMNPDQRNALRRVLQAKDYSLILGMPGTGKTTTTAEIISYLVQMNKSVLVSAYTHTALDNVLVKVREQGVDVLRLGNIDKVMPSMRDCVPSVNSTITSVHEMQEYYKSKRVVGVTCLGIGDIMLQKRQFDYCIIDEASQITLPTCIGPLRYADRFVLVGDLYQLPPIIRNKEAKDGGLDKSLFATLAEARPESICYLEHQYRMCKEIMDVSNLLIYDGKLKCGSHAVAQKQLSLPNIKTGLQEMHQSTSCAGLSSCWLKSVVDPNRKVIFVDTDKLQVKESRPFGSYVQNDTEATLIEHTAEALLNCGLKQDQLAIISVYRSQLRLISQLLKKRPKIEIATIDKYQGRDKECVILSLVRSNTQGNTGDLLRDWRRLNVAITRAKSKLILFGSLSTLKSSALYSHLIDMFEQKEWIYHLAFGSETMHLVEEEENERQIPKDKKTHKTFSPTTKILKENQILKELHQFAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N6E6</accession>
    <name>A0A1C7N6E6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Long-chain-fatty-acid--CoA ligase 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">lcf2_0</name>
        <name evidence="7" type="ORF">A0J61_07782</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>a long-chain fatty acid + ATP + CoA = a long-chain fatty acyl-CoA + AMP + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:15421"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57560"/>
            <dbReference type="ChEBI" id="CHEBI:83139"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.2.1.3"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the ATP-dependent AMP-binding enzyme family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000546">
        <property type="protein sequence ID" value="OBZ84169.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N6E6"/>
    <dbReference type="FunCoup" id="A0A1C7N6E6">
        <property type="interactions" value="231"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N6E6"/>
    <dbReference type="InParanoid" id="A0A1C7N6E6"/>
    <dbReference type="OrthoDB" id="1700726at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005811">
        <property type="term" value="C:lipid droplet"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004467">
        <property type="term" value="F:long-chain fatty acid-CoA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035336">
        <property type="term" value="P:long-chain fatty-acyl-CoA metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="entry name" value="N-terminal domain of ligase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_synth/lig_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43272:SF83">
        <property type="entry name" value="ACYL-COA SYNTHETASE LONG-CHAIN, ISOFORM J"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43272">
        <property type="entry name" value="LONG-CHAIN-FATTY-ACID--COA LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56801">
        <property type="entry name" value="Acetyl-CoA synthetase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 7" id="KW-0436">Ligase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AMP-dependent synthetase/ligase" evidence="6">
        <location>
            <begin position="85"/>
            <end position="502"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00036813"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OBZ84169.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="671" mass="74738" checksum="F9BD590D7DD6ABB5" modified="2016-11-30" version="1">MAQNLFSIPVTEALAGEGPVYRSILSPSKLMTTPAEGVETLYDVLQYAAIQFPDRHAFGYRELLDTISKTKKVTKTVNGKEITEDKTWTYFKLSHYHYYSYAQAAEKTKAIGAGLVQLGLRKHSRVQVSASTSVEWMLMAHEMLTTWISQAMTIVTAYDTLGPEGLQHSIVESEASLCFVNHDQLAALSSIISACPTINAIVYRGKADPDHLTKLRQQGQIKHIMSFEELETLGHQHPIQVVKPQSDELCCIMYTSGSTGQPKGVMLTHGNVVSAIAGVCRMLQHLLEANDTILAYLPLAHVLEFLVENLCIFLGVTLGYGSVRTLTDASVRDCKGDLQEFAPSIMTGVPQVWETIRKTVLSKVAERGPRIQKVFMGAVGLKRYLRQYGLPTTALDRVIFKNVNQQLGGRLRYCLSGGAPVSAETQDFLSLTVCPILAGYGMTESMCAIMAPEQWALTEVGAPVPCVEVKLVDQPELGYLSSNPSPQGEIWIRGPSITLGYYKRDDITKETLEDGWLKTGDIGEWTHRGTLKIIDRVKNLVKLSHGEYIALEKLESVYKSHVMIENMCVYADPLYPKPVGLLVPLEAPLRQLVDDSSTDWETLCHDTKVRQIVLKEMQEQARRAGLKGSEIIADVWLSPEIWTPEMGLMTAAQKLKRNEINKRYEKELKEM</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N730</accession>
    <name>A0A1C7N730_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">glucan 1,4-alpha-glucosidase</fullName>
            <ecNumber evidence="3">3.2.1.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">amyD</name>
        <name evidence="9" type="ORF">A0J61_08827</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Hydrolysis of terminal (1-&gt;4)-linked alpha-D-glucose residues successively from non-reducing ends of the chains with release of beta-D-glucose.</text>
            <dbReference type="EC" id="3.2.1.3"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the glycosyl hydrolase 15 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.3" evidence="3"/>
    <dbReference type="EMBL" id="LUGH01000717">
        <property type="protein sequence ID" value="OBZ83124.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N730"/>
    <dbReference type="FunCoup" id="A0A1C7N730">
        <property type="interactions" value="67"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N730"/>
    <dbReference type="InParanoid" id="A0A1C7N730"/>
    <dbReference type="OrthoDB" id="6123450at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000324">
        <property type="term" value="C:fungal-type vacuole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004339">
        <property type="term" value="F:glucan 1,4-alpha-glucosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000272">
        <property type="term" value="P:polysaccharide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008928">
        <property type="entry name" value="6-hairpin_glycosidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012341">
        <property type="entry name" value="6hp_glycosidase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011613">
        <property type="entry name" value="GH15-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000165">
        <property type="entry name" value="Glucoamylase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31616:SF9">
        <property type="entry name" value="GLUCOAMYLASE, INTRACELLULAR SPORULATION-SPECIFIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31616">
        <property type="entry name" value="TREHALASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00723">
        <property type="entry name" value="Glyco_hydro_15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00736">
        <property type="entry name" value="GLHYDRLASE15"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48208">
        <property type="entry name" value="Six-hairpin glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="6" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GH15-like" evidence="8">
        <location>
            <begin position="35"/>
            <end position="432"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001863"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006188"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OBZ83124.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="441" mass="50039" checksum="B7E51ECFAAD71011" modified="2016-11-30" version="1">MATGNYAYQDQIILSTVDSRIDKWIAQQQVISYHAMLKNINPPGTRQGFFAASLSTYHPDYFYTWTRDAALVARVLTHLPETNSSLLKDFVEFQLETQTTSTVCQCLGEPKFYPNGSGYQGSWGRPQNDGPAERAITWMLIAKRLNEPDYTEYLLPALIKDLTYLTEVWQQPCFDLWEEVEGVHFHTLMVMRRALLDAVDFLQGTSYPTDHYRSTARAIEARLETFWSEEHKRVIVTQDRQRGVPKPSQLDVAVLLAANLVASRQDGFFSPGSDKMLATAVALEDAFRALYPINQDLNGLGTSIGRYPDDIYDGYGLSLGNPWFLATAAYTELYYLAIDEWKQHGLVMNEINRVFFERIVTVCPNATYLAPDSFALDQLVTQVKQKADRFLWTIEYHQAHNGSMSEQFDRVTGFMAGARDLTWSHAAFISAVQAKLGTPIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N7C4</accession>
    <name>A0A1C7N7C4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">LysM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">A0J61_07010</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000452">
        <property type="protein sequence ID" value="OBZ84947.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N7C4"/>
    <dbReference type="STRING" id="101091.A0A1C7N7C4"/>
    <dbReference type="InParanoid" id="A0A1C7N7C4"/>
    <dbReference type="OrthoDB" id="2290084at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00118">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.350.10">
        <property type="entry name" value="LysM domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018392">
        <property type="entry name" value="LysM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036779">
        <property type="entry name" value="LysM_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01476">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00257">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54106">
        <property type="entry name" value="LysM domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51782">
        <property type="entry name" value="LYSM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008889528" description="LysM domain-containing protein" evidence="2">
        <location>
            <begin position="20"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="domain" description="LysM" evidence="3">
        <location>
            <begin position="29"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="87"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="88"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="101"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="137"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="156"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="197"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="214"/>
            <end position="237"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OBZ84947.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="252" mass="27829" checksum="6F737C7204385C89" modified="2016-11-30" version="1">MKSLAIASSIVSFLSIASAIDHFPHPCQQTHIVTADETCQTIASKYDTSVSEIESWNKEFKDFFNCDTVKAGETICVEYSTSIEKRGVSKSKNVKKTNPKGKKEDKKTTKKASDKNKQIKKKASHKDQQAAKKSSHKDKQASKKVEHKNKSDPKKASHKVKHAAKKVTHKKAKQAIKNKKTSSKAKKASQKAKQASKKSDTKAKKIAQKENHAAKKAAKKEKKASHKAKHAVKKGGHASKEATKKKIQAKHA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N7G0</accession>
    <name>A0A1C7N7G0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Cell division control protein 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">CDC3_0</name>
        <name evidence="6" type="ORF">A0J61_07381</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000495">
        <property type="protein sequence ID" value="OBZ84566.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N7G0"/>
    <dbReference type="FunCoup" id="A0A1C7N7G0">
        <property type="interactions" value="172"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N7G0"/>
    <dbReference type="InParanoid" id="A0A1C7N7G0"/>
    <dbReference type="OrthoDB" id="416553at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005938">
        <property type="term" value="C:cell cortex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032156">
        <property type="term" value="C:septin cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01850">
        <property type="entry name" value="CDC_Septin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000196">
        <property type="entry name" value="Cell division control 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030379">
        <property type="entry name" value="G_SEPTIN_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016491">
        <property type="entry name" value="Septin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18884">
        <property type="entry name" value="SEPTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00735">
        <property type="entry name" value="Septin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006698">
        <property type="entry name" value="Septin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51719">
        <property type="entry name" value="G_SEPTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="6" id="KW-0132">Cell division</keyword>
    <keyword evidence="2 3" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Septin-type G" evidence="5">
        <location>
            <begin position="37"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="373"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="373"/>
            <end position="396"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU004560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51719"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OBZ84566.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="416" mass="48258" checksum="3D482EE4A6A3BDFB" modified="2016-11-30" version="1">MSDQTTNSGITILRKKLQGYVGFANLPNQVHRKSVKKGFQFTCMVVGESGLGKSTLVNTLFNTQLYPPKETAELSHETTQTVEVKSITSDIEENGVKLRLTVVDTPGFGDFVNNEESWKPILDNIESRFDAYLEQENRVNRRRMADNRIHACIYFIAPTGHALKPLDIEFMRRLHTRVNLIPVVAKADTLTEEEVAAFKQRILADIAYHKIQIYQAPVYEYDDQETIAENREIMSKIPFAVVGSDKEFEVEGGRLVRGRRYPWGVIEVDNEEHCDFVKLRQMLIRTHMEELKEYTNDVLYENYRTEKLTAMGIQQDPSVFKEVNPVQKMEEERIAHEQKLAKMEAEMRSVFQAKVQEKEAKLKQSEEELYARHKEMKDALEKQRADLEEKKRRLESGRPMTPEKTTKKKGFSFNNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N7V5</accession>
    <name>A0A1C7N7V5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Uncharacterized protein C26F1.08c</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">A0J61_06716</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000419">
        <property type="protein sequence ID" value="OBZ85235.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N7V5"/>
    <dbReference type="InParanoid" id="A0A1C7N7V5"/>
    <dbReference type="OrthoDB" id="68611at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018823">
        <property type="entry name" value="ArAE_2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018820">
        <property type="entry name" value="BRE4-related_DUF2421"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052430">
        <property type="entry name" value="IVT-Associated"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049453">
        <property type="entry name" value="Memb_transporter_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47804">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47804:SF1">
        <property type="entry name" value="DUF2421 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10337">
        <property type="entry name" value="ArAE_2_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10334">
        <property type="entry name" value="BRE4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13515">
        <property type="entry name" value="FUSC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="336"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="362"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="392"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="420"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="449"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="486"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="937"/>
            <end position="956"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="988"/>
            <end position="1008"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="1014"/>
            <end position="1032"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="1070"/>
            <end position="1092"/>
        </location>
    </feature>
    <feature type="domain" description="Putative ER transporter 6TM N-terminal" evidence="8">
        <location>
            <begin position="419"/>
            <end position="651"/>
        </location>
    </feature>
    <feature type="domain" description="Integral membrane bound transporter" evidence="9">
        <location>
            <begin position="960"/>
            <end position="1087"/>
        </location>
    </feature>
    <feature type="domain" description="DUF2421" evidence="7">
        <location>
            <begin position="1098"/>
            <end position="1354"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="622"/>
            <end position="649"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="666"/>
            <end position="695"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="10"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="667"/>
            <end position="695"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF10334"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF10337"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF13515"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OBZ85235.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="1379" mass="157825" checksum="499243E39327C1C7" modified="2016-11-30" version="1">MLKGNKEAQSKSVSSTNQSATSDSPLLRRYPESKTPVVQTSSTVFPLPSVSCKSTFSTQTFHTAVDEQEEEQNELDKPQLERIVERRPLKMIVHPSSNSGAEGLIINRTSQLIKRINTNDFGLSYHPTSTIPMTASTSNNSMMANHLSLIHSMAASIPSNYYYYGSLDNGFLSRSPAGSYFPDNYSEDYEVVLDDGTRQKRSVSLSTLPPLSPLEPGRKHKGNYNHLYYIESNELSGRNEDTDERNQAEEFYQFLLADEERRTRLATTASSDPSVTVQNLQPDTLSDDSEDEYYQTLKKRYKARHEERAHRTCNYLKDVYAWLVRHSITLSHKQKMVLKCSFAYLLGSLFTFVPFFHNFLGSAKLSSHVIATVTVFFLPSKTVGGMVEAAGFGLLYTLCAIVVSLLSMLVAIYLRSEGYYVTSCCVTLGFWLAGSTFVLSFIKAYYNKPTIGTGCGLGFMIIFPVLVREGMVVPAEFDPTYMQEMFAIVTIGTALSVFVCWFIWPMTATKQLKSDINDTLMAIRILLKLLTKTFLLDTDLPEFTANENLQNAINSHRTSFTSLQSSLEDAKKEFYNLHIWQHAAEYDTIVSSLQRLAQHIGGLRSSCGLQFEVMKTGDKNRPNAYGTFTQPQQGSSDSKSSKKKGVYHIKPTDQRKKLEYEMKREQTISSQSIANRSNDFNETESNQKPMRPSLSSYYDFDQPSGEDGALVQFIKTVRRPMKSLAFTCKQTIVHLQSRFTGQTTDRTPSFALLRQNLAMAMSIFEESQQLALTRMYQRKMKNASKKKYTLDPKELQSHLMTQFPAEDVFLVYFFVFCLLEFAKELLVLVECVQSVFEEEERKNDRSTWFYINKYLIQPFWFVCCCFFTKSNAQSSPYEDHLAKINQLKKKSSIDTLVPNNNNTLNTLHTPKPKTKIRRFFLNLWGFFSWFRKHTVRYGLKATFISVIIASLAFFPMTRDYFVNWKMDWMLITVTAVMSPTVGGTNQVAILRVLATMLGSIIAVLFYWLLPHDGLTLLFMTWAFSVPCFWVILNHKHGRFGMFSLLSYNLVVPYMYNHQNEDPPVDLIELAFMRCATVSAGVIVGLFVTAYVWPFEARREMRKGLSDLLIRLSWLYKQLVSEYSEDQSPLTSQPEMAYSQMVKQVIKNPTDPYTNRTLTSCEELEALARRNEQRSFQFQQAELSLQVTLVELQGLLAHAPNEPRLKGPFPVKTYEAILESCQTILDKFLSIRIIILKDVWATQVRRDLMLPASQELMEMAGSVLLYFYLLASALQLKTPLPPYLPPAEQAREKLMLKLQKMPKIPADLKKNHDFTFDSEAVKDECYMVYYAYVVMMESIIIELDKLGQRMKELFGSLVPDEQWARCFGLTDIENDQRKLY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N8B9</accession>
    <name>A0A1C7N8B9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="1">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">FRK1_1</name>
        <name evidence="13" type="ORF">A0J61_08360</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="1"/>
    <dbReference type="EMBL" id="LUGH01000635">
        <property type="protein sequence ID" value="OBZ83594.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="FunCoup" id="A0A1C7N8B9">
        <property type="interactions" value="257"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N8B9"/>
    <dbReference type="InParanoid" id="A0A1C7N8B9"/>
    <dbReference type="OrthoDB" id="193931at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106310">
        <property type="term" value="F:protein serine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035556">
        <property type="term" value="P:intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000571">
        <property type="entry name" value="Maternal embryonic leucine zipper kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000003">
        <property type="entry name" value="Non-specific serine/threonine protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.310.80">
        <property type="entry name" value="Kinase associated domain 1, KA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028375">
        <property type="entry name" value="KA1/Ssp2_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001772">
        <property type="entry name" value="KA1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24346">
        <property type="entry name" value="MAP/MICROTUBULE AFFINITY-REGULATING KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24346:SF110">
        <property type="entry name" value="NON-SPECIFIC SERINE_THREONINE PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02149">
        <property type="entry name" value="KA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103243">
        <property type="entry name" value="KA1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50032">
        <property type="entry name" value="KA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 13" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="11">
        <location>
            <begin position="19"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="domain" description="KA1" evidence="12">
        <location>
            <begin position="938"/>
            <end position="988"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="371"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="687"/>
            <end position="716"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="757"/>
            <end position="792"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="371"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="760"/>
            <end position="771"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="772"/>
            <end position="786"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="52"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="OBZ83594.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="996" mass="113054" checksum="BD057D25D835C153" modified="2016-11-30" version="1">MKSLFTEPNHQKSTSFGPYELLQTLGEGEFGKVKLGVHVETGQEVAVKLIKKEREANNRISKIEREVSILRTLNHPYIVKLHNVIETEKHIGIILEYAPGGELFEYILAHRYLKEKDAKRFFAQLISGVYYMHKRKIVHRDLKLENILLDKNRNIVVTDFGFANQFASAADDMMATTCXSPCYAAPELVINPGLYAGSAVDVWSCGVILYAMLCGFLPFDDDPSNPDSDDINQLYRYILSTELMFPSYVSSESRNLLKKILVTDPTKRCSLEYIIKHSWLKEYHTFIVRDSQPAESKRNSINSISKSQLGMRFYTNQLSASSAFSASTKRDSRILQIKESHLPTIELYRETSTSNEKYSSQPEEHLQKTSGFNYSQNDQSSNTMTTNSQVDSTSDKKQLSGPKSVKNDSAIAVMFCESQHKDTQVIPEKSLSSPLLNQSEQHKSCLIDLSRNLLHRRGSEKLMGFLTKTKNIYEVPNIDTAFEETEEDETSSVEDMNKRSEISCTFNDRLQEHTVNSLAQNTDMRLSVKLVEEDAQRYDSFNNEQKNGSIAHDLRPKEICSLKLEQEDQISADVMYNQGVRSFKEAKGLEQRCNFFKSQPINSKLVASSPPIQAGTAAPSSKVKIVEPSISMRVSMSESGKKAIEAVRRSIYRKHKNHTPDSDNKNTSPLKSRLEEEDLFENVSRPHRNTWAAPPRTHKPATFEEPPAAKSKGKKMMDWIRKKSHSKEQKRASIAVVTNLSSQVSGRNQNMDINYRYKPTKNNAQKQTLPSSERKPVSKNEPRQEDTIPSPLPIAHINERDTKEQSEEIIDIPDRSSLFYNNQVQSLSETALVKLRKQEFKPPTTDGLKFHQGAIDRTALTTQAPTITIRKLKRILNVLGIEVREENKFALKCTRRKANASPNQDIKDETSDDLDSSSILSDITPAGQGLEPIFGSAGIDNGEEVRFSVEICQIRNLPKLYVVDIRRIKGNAWIYKFLYHKLTGLLNLEQENYIAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N8F5</accession>
    <name>A0A1C7N8F5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Endochitinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">CHIT</name>
        <name evidence="11" type="ORF">A0J61_06585</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Random endo-hydrolysis of N-acetyl-beta-D-glucosaminide (1-&gt;4)-beta-linkages in chitin and chitodextrins.</text>
            <dbReference type="EC" id="3.2.1.14"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the glycosyl hydrolase 18 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000404">
        <property type="protein sequence ID" value="OBZ85361.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N8F5"/>
    <dbReference type="STRING" id="101091.A0A1C7N8F5"/>
    <dbReference type="InParanoid" id="A0A1C7N8F5"/>
    <dbReference type="OrthoDB" id="448446at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008061">
        <property type="term" value="F:chitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008843">
        <property type="term" value="F:endochitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006032">
        <property type="term" value="P:chitin catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000272">
        <property type="term" value="P:polysaccharide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.50.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011583">
        <property type="entry name" value="Chitinase_II/V-like_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029070">
        <property type="entry name" value="Chitinase_insertion_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001223">
        <property type="entry name" value="Glyco_hydro18_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001579">
        <property type="entry name" value="Glyco_hydro_18_chit_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050314">
        <property type="entry name" value="Glycosyl_Hydrlase_18"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11177">
        <property type="entry name" value="CHITINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11177:SF392">
        <property type="entry name" value="HAP41P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00704">
        <property type="entry name" value="Glyco_hydro_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00636">
        <property type="entry name" value="Glyco_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01095">
        <property type="entry name" value="GH18_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51910">
        <property type="entry name" value="GH18_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="3" id="KW-0146">Chitin degradation</keyword>
    <keyword evidence="5 7" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="2 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008889546" evidence="9">
        <location>
            <begin position="25"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="domain" description="GH18" evidence="10">
        <location>
            <begin position="40"/>
            <end position="416"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000822"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000489"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU004453"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="OBZ85361.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="416" mass="46539" checksum="13EEDF26EB675E39" modified="2016-11-30" version="1">MRSQAIGLILSTLLLFFSFAAVNASDIEKRAASKKTYGKHRLIAYVVDWELPKSVKWDLLDHVVYSFSEPDAQGNMKGFTGSLLQSFTNKAHQHNVGVSISVGGWSGSKYFSSLVRTDASRKKLAKNIVQLVSEHNLDGVNLDWEYPNDPNGMTCNQRQVTYILYKDTANYLTFIKLLRKSLDAKFTKAHKMITLAVSTRPFNDEKGHPISRLDKAWATNVDSFYIMSYDISGSWMNQAGPNAPYKASSEKYYESSVIQSIDAWHKAGIPKNQLVAGMPFYGTVLQTKQKVTSSSGLYVKLSNKGSIKGDKYDEYAADGCPGSTKSYSGNYQWRSVVADGIIKQQHGWKTYWDSRSMTPYAFNNKGNKILTFDNAKSLKGKANYVKSQRLGGAMIWSLEMDDSSNTLLNSLQAVRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N8I8</accession>
    <name>A0A1C7N8I8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_06541</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000400">
        <property type="protein sequence ID" value="OBZ85403.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N8I8"/>
    <dbReference type="InParanoid" id="A0A1C7N8I8"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="45"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="50"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ85403.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="78" mass="8858" checksum="841B1E119A245DB9" modified="2016-11-30" version="1">MVTEFNVLWLLCLGLLFTAFFLIFKRKRAENTYLATVHTTMDTPLPPLNSSSHGPAHFSAPPPPPPSYQDFRKDVRIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N8M3</accession>
    <name>A0A1C7N8M3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Oleate-induced peroxisomal protein POX18</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">POX18_0</name>
        <name evidence="2" type="ORF">A0J61_08253</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000619">
        <property type="protein sequence ID" value="OBZ83694.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N8M3"/>
    <dbReference type="STRING" id="101091.A0A1C7N8M3"/>
    <dbReference type="InParanoid" id="A0A1C7N8M3"/>
    <dbReference type="OrthoDB" id="10265837at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1050.10:FF:000001">
        <property type="entry name" value="Putative Non-specific lipid-transfer protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1050.10">
        <property type="entry name" value="SCP2 sterol-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003033">
        <property type="entry name" value="SCP2_sterol-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036527">
        <property type="entry name" value="SCP2_sterol-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10094:SF25">
        <property type="entry name" value="SCP2 STEROL-BINDING DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10094">
        <property type="entry name" value="STEROL CARRIER PROTEIN 2 SCP-2 FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02036">
        <property type="entry name" value="SCP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55718">
        <property type="entry name" value="SCP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SCP2" evidence="1">
        <location>
            <begin position="19"/>
            <end position="121"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02036"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ83694.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="130" mass="14017" checksum="7A660E9248DF7FC5" modified="2016-11-30" version="1">MSDIKTPGFQSSEVFEALNKSLQALPADEKAKLIKQVNGVFEFVVKNDKSKTETFTVDLKKEGTVKKGKGSGKADAIMSIGDADFVQLASGKLNGQKAYMSGKLKIKGQMMLATKLDTVFKKLAGNKAKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N8Z9</accession>
    <name>A0A1C7N8Z9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Fungal lipase-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">A0J61_06339</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000379">
        <property type="protein sequence ID" value="OBZ85603.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N8Z9"/>
    <dbReference type="InParanoid" id="A0A1C7N8Z9"/>
    <dbReference type="OrthoDB" id="2338663at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004806">
        <property type="term" value="F:triacylglycerol lipase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00519">
        <property type="entry name" value="Lipase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002921">
        <property type="entry name" value="Fungal_lipase-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044819">
        <property type="entry name" value="OBL-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46086">
        <property type="entry name" value="ALPHA/BETA-HYDROLASES SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46086:SF3">
        <property type="entry name" value="TRIACYLGLYCEROL LIPASE OBL1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01764">
        <property type="entry name" value="Lipase_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="7"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="34"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="91"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="domain" description="Fungal lipase-type" evidence="3">
        <location>
            <begin position="249"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="domain" description="Fungal lipase-type" evidence="3">
        <location>
            <begin position="418"/>
            <end position="501"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="294"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="401"/>
            <end position="420"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01764"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OBZ85603.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="625" mass="70702" checksum="A2F33A7440A1E0A8" modified="2016-11-30" version="1">MAKGRNRLYFAIAFVISSIPSIFGFYALQHDLTLLGSLLFALSLISLGLSTFLFLGYKTVKHGTPMILAVLASISRCLTPLSRLLARTIILGPLLAMIIRTFFFLGFIVLLMSDQLIRALFRYFIGKHPSGRDYSITSAMDPHLALFDPSIPKSNYLENSELFKQRKELRMTEQDGPESRALTALLKRPKYSVSLAYTLSVASKLVYEDVDVIKHELKKSGFNVDTAFRPIAYKNICAFITEKDDDILLVFRGTNPLNIQNYITNITFNMTEIKSSWGSMGRVHKGFWKAMGEPPVRRKTSTTSEDTVDHLSHDTLTPPIKNAAVLRIELTNTSVYRTIMSAIQGTAKIISFLSTNLFHHVKEPIDSTWVGPDIDIRSNSMFLQAEQHILSLIMMDPESIQKSRDEKRRSGLAHGRSTSWQKKKRKRLFITGHSLGGAMGTIFLAKMLQSKSPLLEHFAGLYTFGQPKIGDAEFAKVFSPSMTSKIFHHVYNNDIIPRIPIPGDYDTPPGSLVYIDSAYNITIYPPNPYTNEPVPVRSISFLHLSGLLNRYVIRRLPQENRIRILFRILFPFFLNDHFPCDYSESLRKGRVQNVIMGAGGLEGGHEDQFKKRQRRYSIVDVSSSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N967</accession>
    <name>A0A1C7N967_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Biotin--protein ligase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">bpl1</name>
        <name evidence="4" type="ORF">A0J61_06279</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the biotin--protein ligase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000372">
        <property type="protein sequence ID" value="OBZ85673.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N967"/>
    <dbReference type="FunCoup" id="A0A1C7N967">
        <property type="interactions" value="432"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N967"/>
    <dbReference type="InParanoid" id="A0A1C7N967"/>
    <dbReference type="OrthoDB" id="10250105at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004077">
        <property type="term" value="F:biotin--[biotin carboxyl-carrier protein] ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd16442">
        <property type="entry name" value="BPL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03144">
        <property type="entry name" value="GATase1_ScBLP_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="entry name" value="Bira Bifunctional Protein, Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019197">
        <property type="entry name" value="Biotin-prot_ligase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004408">
        <property type="entry name" value="Biotin_CoA_COase_ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004143">
        <property type="entry name" value="BPL_LPL_catalytic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00121">
        <property type="entry name" value="birA_ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12835">
        <property type="entry name" value="BIOTIN PROTEIN LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12835:SF5">
        <property type="entry name" value="BIOTIN--PROTEIN LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03099">
        <property type="entry name" value="BPL_LplA_LipB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09825">
        <property type="entry name" value="BPL_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="Class I glutamine amidotransferase-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="Class II aaRS and biotin synthetases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51733">
        <property type="entry name" value="BPL_LPL_CATALYTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4" id="KW-0436">Ligase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BPL/LPL catalytic" evidence="3">
        <location>
            <begin position="369"/>
            <end position="566"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009934"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51733"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OBZ85673.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="643" mass="71564" checksum="D002E1EF8E060DA1" modified="2016-11-30" version="1">MNVLIYQGNGTSPTSVKQTYLTLKSILGHAYDVMKVDADTLKSEPWEETCSLIVIPGGRDSPYCEDLNGLVNSKIRHYVQEGGRYLGFCAGAYYASHDIEFEKGSPLQVIGQRELAFFPGTSRGTMYPGFVYNSEKGARAVSVKTEDGLLKSYYNGGGYFVDAHTFDQVKVVCTYQDPGLSGDEVDSAAGVECQVGKGSALLFGIHPEYNIHLVDLSDNDHQADIIRDLSASLPACQAFLTQALARIGLKTRKEAVKSVPQLTPLYLSTLSGQLLKSITEKLQQNTNQDRLFKDSNDAFYIGPLDNSGNDVADMLTRLSLERESEDRSPVLKILYPALSNEQQVHAPHKTLTPLFDIKAYFDALVSRRKQEWGGGAWYRFGNAILYSEVITSTQTVLDKNYEFAEALPSGLVCLATNQIAGRGRGRNSWVSQAGALQFSFVVRHPLQLSNAPVVFIQYLIALAIVESIRTRPGYESVPLRLKWPNDIYADLPDGLKKVGGLLVNSSFAKNEFLLVIGCGVNLNNPHPTVSINDVIQQHNPSLKRLEREEVLAHALVTFEKYYMEFCEKGMGSWFLDKYYQRWLHSDKMVTLTTHDNEKAKIVGITRDYGMLEAVSVNDPRKRFTLQPDGNSFDMLKGLIVKKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N9A4</accession>
    <name>A0A1C7N9A4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Calcium permeable stress-gated cation channel 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">A0J61_06253</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the CSC1 (TC 1.A.17) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000369">
        <property type="protein sequence ID" value="OBZ85695.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N9A4"/>
    <dbReference type="FunCoup" id="A0A1C7N9A4">
        <property type="interactions" value="91"/>
    </dbReference>
    <dbReference type="InParanoid" id="A0A1C7N9A4"/>
    <dbReference type="OrthoDB" id="1689567at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005227">
        <property type="term" value="F:calcium-activated cation channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045122">
        <property type="entry name" value="Csc1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003864">
        <property type="entry name" value="CSC1/OSCA1-like_7TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027815">
        <property type="entry name" value="CSC1/OSCA1-like_cyt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032880">
        <property type="entry name" value="CSC1/OSCA1-like_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13018">
        <property type="entry name" value="PROBABLE MEMBRANE PROTEIN DUF221-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13018:SF5">
        <property type="entry name" value="RE44586P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14703">
        <property type="entry name" value="PHM7_cyt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02714">
        <property type="entry name" value="RSN1_7TM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13967">
        <property type="entry name" value="RSN1_TM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="49"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="121"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="194"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="438"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="483"/>
            <end position="511"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="532"/>
            <end position="550"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="636"/>
            <end position="667"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="688"/>
            <end position="708"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="714"/>
            <end position="733"/>
        </location>
    </feature>
    <feature type="domain" description="CSC1/OSCA1-like N-terminal transmembrane" evidence="10">
        <location>
            <begin position="49"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="domain" description="CSC1/OSCA1-like cytosolic" evidence="11">
        <location>
            <begin position="236"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="domain" description="CSC1/OSCA1-like 7TM region" evidence="9">
        <location>
            <begin position="436"/>
            <end position="708"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="772"/>
            <end position="825"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="772"/>
            <end position="787"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007779"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF02714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF13967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF14703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="OBZ85695.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="1030" mass="117738" checksum="9889E408E3B87097" modified="2016-11-30" version="1">MEELATTSVNTSTSTVAGFPCIWIFKFLCEDEEPLPGSPAQTSKSPTGFATQLILCTSVGFVCFLLFCFLRVRWTTIYSPRLRMRKHAPEELPATFFGWIIPLLKTPNSVVMEKVGLDAVVMLQFLLMSVKLFGFCGFFGTVVLYPISRMGGNFANGTLPEQPNNTLYSLSEQHQEFFATRLGTNFNAHSVSFLWVYLFFTYLFVFATFYFTFLNYRDYVRIRREFLLRKARTLSSRTLLITGIPPHLRSDRRLADYFEKLGIGVVQSVHLIRHVERLLEFIKERAQHLRQLETAYANYLGNPVEDPSYDPEEILNYQDAREAQCADGAELPHFLKSRERPIARQGYIWGSKMDAIDYYTEQFDEVDELVVKARKVGKFLPTSVGFVTFEETISAYVASQVLIDSTPFRLRAQLAPEPRDVLWENIAMHGRERVIRKFLIMFVLLFLVFSWTIPCNYLSALTSTKSLKAYFPWLLKLAEKNKIINQIVAGFIPTLGVVIFFSILPLIFNSLSVIEGFTTRSEAEESCFAKQFFFLFANVLLFITVTSTLFKSQKDIFEDPIKIANIFASKLPEVAPFYINYAVLQGIMLCPIQLLQIGPIIVQQFYRTFLCKTPRDYAEVSAPRMYNFGWGYPVPVFMFVVVLVYSTISPLILVFGVIYFAMSYLVYKYQLLYVYFHSYEVAGRMWPLVFTRIIIGLLIFELTSAGLFTLNKSYPMAALCLPLVIMTIAYKFMMDRAYQRSTQFLPLKLLAEKLGPMKTIALEGQMLHQQQQQQQQQQQQQQQQQQQSVVSESPTEMTHPPPPAPQAMMPDVHSAESSNNNTMIIRRIRKRRTVLDEDDYVADPRKFTDFREPPMTLLNGILNTGMKQYGHPALLGVLPQLWLPVKAGSENNRAIMNHSTSVSHSSSFNSFASSTVMADKQQPIIIPKETQPLLLRSEGAAGRSVVNEADSIVSMPIDDDVEGGNTDQEEEEDNVGTYYHHPERRLSKNLLSQSYGATSISSQISNQPVKKKKNKRFLSKNMRKFSSFFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N9F0</accession>
    <name>A0A1C7N9F0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Protein THEM6</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_06202</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the lcsJ thioesterase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000364">
        <property type="protein sequence ID" value="OBZ85743.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N9F0"/>
    <dbReference type="InParanoid" id="A0A1C7N9F0"/>
    <dbReference type="OrthoDB" id="265761at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00586">
        <property type="entry name" value="4HBT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.129.10">
        <property type="entry name" value="Hotdog Thioesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029069">
        <property type="entry name" value="HotDog_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051490">
        <property type="entry name" value="THEM6_lcsJ_thioesterase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12475">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12475:SF4">
        <property type="entry name" value="PROTEIN THEM6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13279">
        <property type="entry name" value="4HBT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54637">
        <property type="entry name" value="Thioesterase/thiol ester dehydrase-isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00038476"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ85743.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="222" mass="25659" checksum="8C04F363A547EB56" modified="2016-11-30" version="1">MNSRALAVGVPIGLLLITHLKSLPFAYTVRSWFLLRALIKKAKEKELAPDSLFSSVSQDHRCYLDDIDYNQHMNNSTYNKILDFNRIHVLYAIFPKMMMEPQHRLFGHNAGVITLFRKEIPPLARYKVQSRIWSWNQKWLFLQHRFLLEDGTVACIAISKIVFKRLSGKTVPPSEVMELCGHDLSDPSIEDRRSQNWAIAQNVLSLDAIIQDPYPWQPAAKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N9N2</accession>
    <name>A0A1C7N9N2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF1746 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_06170</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000360">
        <property type="protein sequence ID" value="OBZ85777.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N9N2"/>
    <dbReference type="STRING" id="101091.A0A1C7N9N2"/>
    <dbReference type="InParanoid" id="A0A1C7N9N2"/>
    <dbReference type="OrthoDB" id="5428737at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044695">
        <property type="term" value="C:Dsc E3 ubiquitin ligase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032933">
        <property type="term" value="P:SREBP signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038967">
        <property type="entry name" value="Dsc4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013715">
        <property type="entry name" value="DUF1746"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39405">
        <property type="entry name" value="DSC E3 UBIQUITIN LIGASE COMPLEX SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39405:SF1">
        <property type="entry name" value="DSC E3 UBIQUITIN LIGASE COMPLEX SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08508">
        <property type="entry name" value="DUF1746"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="54"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="domain" description="DUF1746" evidence="2">
        <location>
            <begin position="12"/>
            <end position="111"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF08508"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ85777.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="207" mass="22979" checksum="48B74D05E13219F0" modified="2016-11-30" version="1">MSSNGKRDVLRSIDYLLCCHIAYSYFLDASLLVLFFHILLQLQLLSPRSLNRTLRTALVIVSVGWLVCLLLHATTEPGQAGIIIDFIGNQHKPSMFRLFMLDSTIYILQIVRVLITSSLSSQLLLNGTVVTTITVPPGLATALGAESVTLMLPPREGSDGDESNTDDLFYHNELVVDIELRNSIRNIMYAEMEDPSTARDGSERLPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NA29</accession>
    <name>A0A1C7NA29_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_06046</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000347">
        <property type="protein sequence ID" value="OBZ85900.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NA29"/>
    <dbReference type="STRING" id="101091.A0A1C7NA29"/>
    <dbReference type="InParanoid" id="A0A1C7NA29"/>
    <dbReference type="OrthoDB" id="7763131at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ85900.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="198" mass="22498" checksum="B47AF8BD0D0C461F" modified="2016-11-30" version="1">MSQAQITNDNTVRSNGIGESFSEEDMSFCKAWMAISLNGITGTDQRVMQFFYEQADRKVSGGTSEVDKIVLATSVCRNGHPKSRTRQERLQKPQNEKPLVSRLRFLATEGFKKPRCRKQLEKRNSAKLNLEAAKERMQKRISKRKETHSYSLAQNEMSIAAAILALDPFAPEVQNNPDWANAIKLLSPKSMIAWKKKH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NA33</accession>
    <name>A0A1C7NA33_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Trehalase</fullName>
            <ecNumber evidence="5">3.2.1.28</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Alpha-trehalose glucohydrolase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">ntp1</name>
        <name evidence="8" type="ORF">A0J61_06476</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 5">
            <text>alpha,alpha-trehalose + H2O = alpha-D-glucose + beta-D-glucose</text>
            <dbReference type="Rhea" id="RHEA:32675"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15903"/>
            <dbReference type="ChEBI" id="CHEBI:16551"/>
            <dbReference type="ChEBI" id="CHEBI:17925"/>
            <dbReference type="EC" id="3.2.1.28"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the glycosyl hydrolase 37 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.28" evidence="5"/>
    <dbReference type="EMBL" id="LUGH01000392">
        <property type="protein sequence ID" value="OBZ85476.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NA33"/>
    <dbReference type="FunCoup" id="A0A1C7NA33">
        <property type="interactions" value="51"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NA33"/>
    <dbReference type="InParanoid" id="A0A1C7NA33"/>
    <dbReference type="OrthoDB" id="3542292at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004555">
        <property type="term" value="F:alpha,alpha-trehalase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005993">
        <property type="term" value="P:trehalose catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008928">
        <property type="entry name" value="6-hairpin_glycosidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012341">
        <property type="entry name" value="6hp_glycosidase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001661">
        <property type="entry name" value="Glyco_hydro_37"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018232">
        <property type="entry name" value="Glyco_hydro_37_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011120">
        <property type="entry name" value="Trehalase_Ca-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23403:SF6">
        <property type="entry name" value="CYTOSOLIC NEUTRAL TREHALASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23403">
        <property type="entry name" value="TREHALASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01204">
        <property type="entry name" value="Trehalase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07492">
        <property type="entry name" value="Trehalase_Ca-bi"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00744">
        <property type="entry name" value="GLHYDRLASE37"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48208">
        <property type="entry name" value="Six-hairpin glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00927">
        <property type="entry name" value="TREHALASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00928">
        <property type="entry name" value="TREHALASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="3 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Neutral trehalase Ca2+ binding" evidence="7">
        <location>
            <begin position="78"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="773"/>
            <end position="805"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="14"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="25"/>
            <end position="36"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005615"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU361180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF07492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OBZ85476.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="805" mass="92675" checksum="E8F06A1A898B3FDA" modified="2016-11-30" version="1">MIDNRRESVDPTAPASTYYTSGRNGPRHRTRTHTHKGGSASFNVGDPRETNSSGIMRRASYEDKGKNRRFLIEVESTLTQILEQEDTDGDFQITINDLGPKTLSLGTADSGGYKRFHIRGNYMLSNLLQELALAKDYGRKYIVLDEERLNENPVDRLSKMIRHLFWDGLTRSIDGEGLEAICADPKNRQKDLAPRIYIPYDEKEVYDYYKRVSEEKKHLNLDVQYLPKDITPAYVKSINDKPGLLALAMNRVKDENGNITLSGVPFVVPGGRFNEMYGWDSYFESLGLLADGRINLAKGMAENFAYEIKHYGKILNANRSYYLSRSQPPFLTDLAIRVYEAMDPSNEKENKAWLREILKSAIKEYHTVWMAEPRLDKKTMLSRYRPDGLGIPPETEASHFDHIIQKYADKHNVSIPEFNAMYNDGIVKEPELDEYFLHDRAVRESGHDTTYRFEGVCANLATVDLNALLYKYETDIADCIRDFLDDDLEDFDGNKQTSEVWSDRATKRRERIDKYLWNEKDDLYYDYDTVKEQMTTYESVTSYWMMWAGCASQEQAQKLAKSLYKFEVKGGVVSGTERSRGHITLDRPNRQWDFPFGWAPHQIMTWAAFDKYGMTDIASRLAYRFLYTITKSFVDFNGVVPEKFDVVNLSHQVQVEYGNVGVDFKFISREGFGWMNASFEVGLSHLSTQLRRALGTLTDPDFLFKKMIEDEESKLSETERLEALSRRRVSTIAARDILREEADAAITKIKTEDILRQSYSAPKSPEMIENYLSTTTDHPNANDAKLQPVEEKPVEDYLTVPTSNM</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NA43</accession>
    <name>A0A1C7NA43_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Regulatory protein MIG1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">MIG1_1</name>
        <name evidence="9" type="ORF">A0J61_05948</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000338">
        <property type="protein sequence ID" value="OBZ85993.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NA43"/>
    <dbReference type="STRING" id="101091.A0A1C7NA43"/>
    <dbReference type="InParanoid" id="A0A1C7NA43"/>
    <dbReference type="OrthoDB" id="8922241at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000072">
        <property type="entry name" value="zinc finger protein 143 isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000690">
        <property type="entry name" value="Zinc finger protein 354C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24394:SF29">
        <property type="entry name" value="MYONEURIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24394">
        <property type="entry name" value="ZINC FINGER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 7" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="8">
        <location>
            <begin position="97"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="8">
        <location>
            <begin position="125"/>
            <end position="152"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OBZ85993.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="170" mass="19688" checksum="B812776973CF524A" modified="2016-11-30" version="1">MNYSVTMVPDKQPISYTDSMDLLWSSSCPSMVPMWLDTMPLPYLPNTFPFDPQNDALFYLDWPRHSVADNQSSCSSPLSSPIPSFYEKPKVKTDRPYSCHLCPRAFARKHDLQRHIRVHTGDKPYACPCCKKAFARTDALKRHLRVEEDCRKSQEVQAMKAAGRRRYKNI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NA76</accession>
    <name>A0A1C7NA76_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">A0J61_06427</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000387">
        <property type="protein sequence ID" value="OBZ85526.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NA76"/>
    <dbReference type="STRING" id="101091.A0A1C7NA76"/>
    <dbReference type="InParanoid" id="A0A1C7NA76"/>
    <dbReference type="OrthoDB" id="2143914at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019185">
        <property type="term" value="C:snRNA-activating protein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001006">
        <property type="term" value="F:RNA polymerase III type 3 promoter sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042795">
        <property type="term" value="P:snRNA transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042796">
        <property type="term" value="P:snRNA transcription by RNA polymerase III"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00167">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051575">
        <property type="entry name" value="Myb-like_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017930">
        <property type="entry name" value="Myb_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001005">
        <property type="entry name" value="SANT/Myb"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46621">
        <property type="entry name" value="SNRNA-ACTIVATING PROTEIN COMPLEX SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46621:SF1">
        <property type="entry name" value="SNRNA-ACTIVATING PROTEIN COMPLEX SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00249">
        <property type="entry name" value="Myb_DNA-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00717">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51294">
        <property type="entry name" value="HTH_MYB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50090">
        <property type="entry name" value="MYB_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH myb-type" evidence="8">
        <location>
            <begin position="404"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="domain" description="Myb-like" evidence="7">
        <location>
            <begin position="404"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="65"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="337"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="385"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="459"/>
            <end position="563"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="199"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="65"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="345"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="388"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="470"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="490"/>
            <end position="500"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="519"/>
            <end position="530"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OBZ85526.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="563" mass="65350" checksum="0F1EFA920B1E30B8" modified="2016-11-30" version="1">MQMDTISRLTSAVETPSGGTEKNVTNSSKSLGQLDNIFQSVKKQIEQWGEHAKWKIDLILLDNPQQQQQQQQQQQQQQSSIHPLLSPQHFHPNAITSLSDKSGDSKKKHKQLPVTSTIHYPWDFVPPSNEWKQDSEDLQQKLHESIERQRYLESIIWSQAEQIKHSSNPSEKREDAIRTMRDIYLMSQNEQKMHHLVESNILQKDIDALSNKLKKLTQTLEKIENMELPTEDNDLDKQTLLNDRKVWMRKLHLAELRLSARDAEIEYLHEIIDTLKANAFTPSSPRPQFQKKLRKGPPYLFQQQFSPRSEVRSSEPHPLSGLDSLGIVADQMLSDPEFESNAKSVPEKRLRSRLDDRRSQRSIDSAATLLAMPQLMVPHRAKLEEIHSSPSPEQSKSMEPIPKKPRSTYTRWTEAEDRLLRAAVKKYGHSNWEACSRDVQGRSNIQCRNRWIRHLEHKPPPVEEEEEEEEKPKKMELKPNKVNLERPLQQRHQANNNARQSPSIAALLNSSNDDYHYSPKSTPQLYQEQNAYHIHPNYRPPSPIATPKNGKRRSPEDASVSRW</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NAB0</accession>
    <name>A0A1C7NAB0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Histone-binding protein RBBP4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">Rbbp4_0</name>
        <name evidence="9" type="ORF">A0J61_05896</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000333">
        <property type="protein sequence ID" value="OBZ86047.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NAB0"/>
    <dbReference type="FunCoup" id="A0A1C7NAB0">
        <property type="interactions" value="919"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NAB0"/>
    <dbReference type="InParanoid" id="A0A1C7NAB0"/>
    <dbReference type="OrthoDB" id="427795at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006325">
        <property type="term" value="P:chromatin organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022052">
        <property type="entry name" value="Histone-bd_RBBP4-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050459">
        <property type="entry name" value="WD_repeat_RBAP46/RBAP48/MSI1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22850">
        <property type="entry name" value="WD40 REPEAT FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12265">
        <property type="entry name" value="CAF1C_H4-bd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 6" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="Histone-binding protein RBBP4-like N-terminal" evidence="8">
        <location>
            <begin position="20"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="221"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="264"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="308"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="365"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="410"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="430"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="453"/>
            <end position="463"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF12265"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OBZ86047.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="473" mass="53859" checksum="01B0371C6B2C3916" modified="2016-11-30" version="1">MHYESEINRTEEEQEKLINEEYKMWKKNSPFLYDLVITHALEWPSLTCQWFPDVEDVPDKNYRLQRLLLGTHTNDDEPNYLQIASVRLPKEYTSEDTVMEETQEDSHDTYIKITQKILHDGEVNRARYQVHNPDIIATKSRTGDVYVFDRTKYDPVPKENEKFNPTLRLVGHDKEGYGLAWSPHQKTATHLLSAGFDSKICHWDIAGTIKENRELEPVRTYTAHATGVEDVAWHNKFESIFASVGDDARLMIWDVRNDKPIHNIQAHEAEVNCVSFAPSNEWILATGSGDKTTALWDLRNLKSSLHSLRAHQSEILQLSWSPHHDSVLATASSDRRILVWDLSRIDAPQTPEEAEDGPPELLFMHGGHTNKISDFGWNPAEPWVLSSTADDNIVQVWQMASNIYHPQQVVEETKPSSPASNMTAPPPSSPGSNMTSVTPETQQPNTTPAIHTKIPISESSSPKPNEEEDKMEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NAH2</accession>
    <name>A0A1C7NAH2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Transcription factor ste11</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">ste11_1</name>
        <name evidence="6" type="ORF">A0J61_05937</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000337">
        <property type="protein sequence ID" value="OBZ86010.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NAH2"/>
    <dbReference type="STRING" id="101091.A0A1C7NAH2"/>
    <dbReference type="InParanoid" id="A0A1C7NAH2"/>
    <dbReference type="OrthoDB" id="6247875at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01389">
        <property type="entry name" value="HMG-box_ROX1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.30.10">
        <property type="entry name" value="High mobility group box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009071">
        <property type="entry name" value="HMG_box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036910">
        <property type="entry name" value="HMG_box_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051356">
        <property type="entry name" value="SOX/SOX-like_TF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45789">
        <property type="entry name" value="FI18025P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45789:SF2">
        <property type="entry name" value="FI18025P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00505">
        <property type="entry name" value="HMG_box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00398">
        <property type="entry name" value="HMG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47095">
        <property type="entry name" value="HMG-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50118">
        <property type="entry name" value="HMG_BOX_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2 3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HMG box" evidence="5">
        <location>
            <begin position="10"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="HMG box" evidence="3">
        <location>
            <begin position="10"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="125"/>
            <end position="144"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OBZ86010.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="276" mass="32227" checksum="697C19F28E5F38D1" modified="2016-11-30" version="1">MTKTSNHAGIPRPLNCFLIYRLEKQKEIVAKCAGANHRDISKIIAQWWKNATDEEKRPYREKSRLAKLEHSKLYPDYKYMPKKKTTPKRVYIRKNKKNEFTSRTSQNNELMKLMYRDRRVLEELEDDTGAEESERHRVKHDGNTSPHLTECVNNLSECSLSECLSDKLTPMLSPYPESFADQELASPMMTSQSSYFNPQDYFYNVLNAPRIDDSNAYNPEYLQFIDDEWTYMTYKPCMYATQASSSEVDGYPAYSVPMPNDHAYGLDFIDPSLLLM</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NAK9</accession>
    <name>A0A1C7NAK9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Cytochrome c oxidase assembly factor 5</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_05865</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the PET191 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000330">
        <property type="protein sequence ID" value="OBZ86081.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NAK9"/>
    <dbReference type="FunCoup" id="A0A1C7NAK9">
        <property type="interactions" value="189"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NAK9"/>
    <dbReference type="InParanoid" id="A0A1C7NAK9"/>
    <dbReference type="OrthoDB" id="282149at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033617">
        <property type="term" value="P:mitochondrial respiratory chain complex IV assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018793">
        <property type="entry name" value="Cyt_c_oxidase_assmbl_Pet191"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28627">
        <property type="entry name" value="CYTOCHROME C OXIDASE ASSEMBLY FACTOR 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28627:SF1">
        <property type="entry name" value="CYTOCHROME C OXIDASE ASSEMBLY FACTOR 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10203">
        <property type="entry name" value="Pet191_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007785"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ86081.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="72" mass="8437" checksum="93FC8B79162A62E2" modified="2016-11-30" version="1">MPSSCKEIRQELIECMLKSDCVLIKRNTVKECFKEEHKADVPAECQSIRKSFAECKRGMIDPRMRFRGNKTQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NAL0</accession>
    <name>A0A1C7NAL0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">CCHC-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">A0J61_07553</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000515">
        <property type="protein sequence ID" value="OBZ84404.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NAL0"/>
    <dbReference type="InParanoid" id="A0A1C7NAL0"/>
    <dbReference type="OrthoDB" id="2241864at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.60.10">
        <property type="entry name" value="Zinc finger, CCHC-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001878">
        <property type="entry name" value="Znf_CCHC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036875">
        <property type="entry name" value="Znf_CCHC_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00098">
        <property type="entry name" value="zf-CCHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00343">
        <property type="entry name" value="ZnF_C2HC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57756">
        <property type="entry name" value="Retrovirus zinc finger-like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50158">
        <property type="entry name" value="ZF_CCHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="CCHC-type" evidence="3">
        <location>
            <begin position="197"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="212"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="229"/>
            <end position="238"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OBZ84404.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="295" mass="34641" checksum="FCC0841F9EE4D737" modified="2016-11-30" version="1">MDQDSVFIETTHIKDKMKFKNYLNSFNTGDTYIYYGRQPEERTWQSRTFLETSWDTKSQVYAKLISEGLVMQGEPEPLLKGYRSLPSDVHIVRIKIEQLPFMEPKRLLEQLRERMSHFGEVLHLGLLKDGPCFVGTGYAYLNMDTEPDEPLRPIINWLDDRKRILLTWDHVPPFCYICKKEHHIKTECPVYMNTKLCFKCRKPGHVLKMCPSRKLSSEENSSEDEKSVQNEGSLTPRSEASFVSQERIALFLENLNLMPPAELEKRRLLQSQHLKSLLMFQEKHHGDSEENFIQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NAL6</accession>
    <name>A0A1C7NAL6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_05797</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000324">
        <property type="protein sequence ID" value="OBZ86153.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NAL6"/>
    <dbReference type="InParanoid" id="A0A1C7NAL6"/>
    <dbReference type="OrthoDB" id="2244108at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ86153.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="158" mass="18041" checksum="AAF60790CEF37849" modified="2016-11-30" version="1">MTARSPQTIISSSVNPANLLELKVLSNIVSQLRDQGDMGQAIPYLSKMVQIVDSQRLEKPTDPQNKTAYYSQLNELQKLKADAYSQLAFAYLKTHQFVQCESWLTSSIKLWEKLIRYDPQGQPSLMVAYEALIECYMAMGKDHLAQHIQTRLCKLKET</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NAR3</accession>
    <name>A0A1C7NAR3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">arginine--tRNA ligase</fullName>
            <ecNumber evidence="2">6.1.1.19</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Arginyl-tRNA synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="primary">argS1_1</name>
        <name evidence="12" type="ORF">A0J61_07477</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>tRNA(Arg) + L-arginine + ATP = L-arginyl-tRNA(Arg) + AMP + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:20301"/>
            <dbReference type="Rhea" id="RHEA-COMP:9658"/>
            <dbReference type="Rhea" id="RHEA-COMP:9673"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:32682"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78513"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.19"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 10">Belongs to the class-I aminoacyl-tRNA synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.19" evidence="2"/>
    <dbReference type="EMBL" id="LUGH01000506">
        <property type="protein sequence ID" value="OBZ84474.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NAR3"/>
    <dbReference type="FunCoup" id="A0A1C7NAR3">
        <property type="interactions" value="731"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NAR3"/>
    <dbReference type="InParanoid" id="A0A1C7NAR3"/>
    <dbReference type="OrthoDB" id="68056at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004814">
        <property type="term" value="F:arginine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006420">
        <property type="term" value="P:arginyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032543">
        <property type="term" value="P:mitochondrial translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07956">
        <property type="entry name" value="Anticodon_Ia_Arg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00671">
        <property type="entry name" value="ArgRS_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.730.10:FF:000006">
        <property type="entry name" value="Arginyl-tRNA synthetase 2, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.620:FF:000058">
        <property type="entry name" value="Mitochondrial arginyl-tRNA synthetase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1360.70">
        <property type="entry name" value="Arginyl tRNA synthetase N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.730.10">
        <property type="entry name" value="Isoleucyl-tRNA Synthetase, Domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001412">
        <property type="entry name" value="aa-tRNA-synth_I_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001278">
        <property type="entry name" value="Arg-tRNA-ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005148">
        <property type="entry name" value="Arg-tRNA-synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036695">
        <property type="entry name" value="Arg-tRNA-synth_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035684">
        <property type="entry name" value="ArgRS_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008909">
        <property type="entry name" value="DALR_anticod-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009080">
        <property type="entry name" value="tRNAsynth_Ia_anticodon-bd"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00456">
        <property type="entry name" value="argS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11956:SF11">
        <property type="entry name" value="ARGININE--TRNA LIGASE, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11956">
        <property type="entry name" value="ARGINYL-TRNA SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03485">
        <property type="entry name" value="Arg_tRNA_synt_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05746">
        <property type="entry name" value="DALR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00750">
        <property type="entry name" value="tRNA-synt_1d"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01038">
        <property type="entry name" value="TRNASYNTHARG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00836">
        <property type="entry name" value="DALR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47323">
        <property type="entry name" value="Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55190">
        <property type="entry name" value="Arginyl-tRNA synthetase (ArgRS), N-terminal 'additional' domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52374">
        <property type="entry name" value="Nucleotidylyl transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00178">
        <property type="entry name" value="AA_TRNA_LIGASE_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="5 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 10 12" id="KW-0436">Ligase</keyword>
    <keyword evidence="4 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6 10" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DALR anticodon binding" evidence="11">
        <location>
            <begin position="456"/>
            <end position="571"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005594"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00033033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00049339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU363038"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM00836"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="OBZ84474.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="571" mass="64688" checksum="924F947259EECEE0" modified="2016-11-30" version="1">MSTLSRFRSAIAQPLSHLTQIEKSHISKLLSTPKASSTHQFSLPIPKLVAQADHKPINVAAFCQELAGKFEPNTYIEKATASGPFLQFDVQPLEYIKSTLNQVYNEKDLYGHHTEPINDKKTVVIDYSSPNIAKPFHAGHLRSTILGNFIKRVHDANGYKTIGVNYLGDWGKQYGLLAIGFELFGDSEALVKDPIHHLYQVYVKINELAKSNPDIDQKANAYFKKMEDGDEEALGQWRRFRDLSIESYKEIYHRLNIEFDHYSGESQTEPFIPKVYDLLRERSLLKITEDGAWIIDLEPYKLGKPVIRRADGTSLYMTRDLASIMLRRHLFGSFDKAVYVVGTEQELYLKQLFKICQLLEYPIDLHHANFGRVMGMSTRKGTVVFLQDILDTAKECMLENVRKSNSEMSNHQQELVADRLGASAVMIQDMLAKRVKNYEFSWNRMTAAKGYTGVYLQYTFARMCSIEAKANVPITNEADLSLLKENEAFELALTISQLSDITRSACQSMDPSVIVQYLFRLAHATSQANSALRVKGADAATAEARMLLFWAARTTLANGLHILGIDPLRRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NAU7</accession>
    <name>A0A1C7NAU7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Alpha-soluble NSF attachment protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">Napa</name>
        <name evidence="5" type="ORF">A0J61_05772</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Required for vesicular transport between the endoplasmic reticulum and the Golgi apparatus.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Membrane</location>
            <topology evidence="4">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the SNAP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000322">
        <property type="protein sequence ID" value="OBZ86181.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NAU7"/>
    <dbReference type="STRING" id="101091.A0A1C7NAU7"/>
    <dbReference type="InParanoid" id="A0A1C7NAU7"/>
    <dbReference type="OrthoDB" id="9984275at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031201">
        <property type="term" value="C:SNARE complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005774">
        <property type="term" value="C:vacuolar membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005483">
        <property type="term" value="F:soluble NSF attachment protein activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019905">
        <property type="term" value="F:syntaxin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035494">
        <property type="term" value="P:SNARE complex disassembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd15832">
        <property type="entry name" value="SNAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000744">
        <property type="entry name" value="NSF_attach"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13768:SF8">
        <property type="entry name" value="ALPHA-SOLUBLE NSF ATTACHMENT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13768">
        <property type="entry name" value="SOLUBLE NSF ATTACHMENT PROTEIN SNAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14938">
        <property type="entry name" value="SNAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00448">
        <property type="entry name" value="NSFATTACHMNT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0931">ER-Golgi transport</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 4" id="KW-0653">Protein transport</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010050"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU367013"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OBZ86181.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="273" mass="31692" checksum="452C26E28BF71857" modified="2016-11-30" version="1">MSEHQAQDLLVQAERKLNSWTWFNSTNKHEDAAEIYEKAANTFKLAQRWKDASGAYVKAAEIYKSTPDLQYESSRSFENAAKCLKRIDAQDKQSSNFRNAAKHHQEIAEIYESEIVDLRGAKEHWEAASNLYMADDSPAMINKCLLKVAHFAAQLEEYNVAIDRFEYVATDSMDNQLTKWSIKEYFLKAGLCSMCIGDTVKTRQLINKYCSIDLSFENTREYQFLESILYCQENNDVDLFKQKICEFDQTSKMDNWKISILLKIKNVMMVSIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NAW0</accession>
    <name>A0A1C7NAW0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_05734</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000319">
        <property type="protein sequence ID" value="OBZ86213.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NAW0"/>
    <dbReference type="InParanoid" id="A0A1C7NAW0"/>
    <dbReference type="OrthoDB" id="2284433at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="54"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="138"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="226"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="55"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="73"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="138"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="250"/>
            <end position="261"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ86213.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="291" mass="33161" checksum="B834CB080C2F564C" modified="2016-11-30" version="1">MVHPVVLFGGFFLVAAGVTGYAVLEIMREQQNYQYWEDNIFRHSHDFDFQPYNEKEEEQDKDDEANAYATGRYEPEHKNLKNRKHEDHSQETAEQSDEEISRLETSLTERNKSLLAEKERLDQDEEMLKSKQSILLEQQLSHSHSSGTSDSDIPADNNNESVYYDNNNSFHDDNSDFHDDSNCGINSVYHDSSSSSSRMLDCDFNGISQDLANQIEDSITLLQQQTIQSDSEVDHHSNPFYSEDSDHLDSSSVQLTLSDSEGSWDAISSDDLIPSDSNYGDSATDSEQEDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NAX0</accession>
    <name>A0A1C7NAX0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Sidoreflexin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">fsf1</name>
        <name evidence="10" type="ORF">A0J61_05711</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Mitochondrion membrane</location>
            <topology evidence="1 9">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the sideroflexin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000316">
        <property type="protein sequence ID" value="OBZ86247.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NAX0"/>
    <dbReference type="FunCoup" id="A0A1C7NAX0">
        <property type="interactions" value="102"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NAX0"/>
    <dbReference type="InParanoid" id="A0A1C7NAX0"/>
    <dbReference type="OrthoDB" id="6608471at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015194">
        <property type="term" value="F:L-serine transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015075">
        <property type="term" value="F:monoatomic ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071454">
        <property type="term" value="P:cellular response to anoxia"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006730">
        <property type="term" value="P:one-carbon metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140300">
        <property type="term" value="P:serine import into mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004686">
        <property type="entry name" value="Mtc"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00798">
        <property type="entry name" value="mtc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11153">
        <property type="entry name" value="SIDEROFLEXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11153:SF6">
        <property type="entry name" value="SIDEROFLEXIN-5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03820">
        <property type="entry name" value="SFXNs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0029">Amino-acid transport</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 9" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="138"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="175"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="259"/>
            <end position="283"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU362000"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OBZ86247.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="318" mass="34958" checksum="BC0483A7A8C27509" modified="2016-11-30" version="1">MATPIDLSKPRYPQDTYWGRLLHFVDVTDPRTLFVSGKQLERCKQLLANPTGHHHEELWKAKKVVDSTIHPDTGEPVLLPFRMSCFVPTNMILVAGMLLPNPSIKSILFWQWANQSVNVAFNSANANKTTPMSIKETAIAYVSAVTTSCTLAVGLNQAVPRLQVSPHLKSLCMKLVPFTAVAAAGTVNVFLMRGKEIREGIDVFDDQGHSVGKSKVAGFSAVSQVAISRILTNAPVLIIPPILLGRLQRTRWVQQRPGLVMPLNFGLIALSLMTALPAAIAVFPQIGTLETSKMEKEFQSLKDVHGNPVDRLYFNKGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NAX5</accession>
    <name>A0A1C7NAX5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">AP-4 complex subunit epsilon</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">A0J61_05695</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000315">
        <property type="protein sequence ID" value="OBZ86257.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NAX5"/>
    <dbReference type="STRING" id="101091.A0A1C7NAX5"/>
    <dbReference type="InParanoid" id="A0A1C7NAX5"/>
    <dbReference type="OrthoDB" id="29308at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030117">
        <property type="term" value="C:membrane coat"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016192">
        <property type="term" value="P:vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050840">
        <property type="entry name" value="Adaptor_Complx_Large_Subunit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028269">
        <property type="entry name" value="AP4E1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002553">
        <property type="entry name" value="Clathrin/coatomer_adapt-like_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22780">
        <property type="entry name" value="ADAPTIN, ALPHA/GAMMA/EPSILON"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01602">
        <property type="entry name" value="Adaptin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14807">
        <property type="entry name" value="AP4E_app_platf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01356">
        <property type="entry name" value="AP4E_app_platf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0653">Protein transport</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="domain" description="AP-4 complex subunit epsilon-1 C-terminal" evidence="5">
        <location>
            <begin position="678"/>
            <end position="782"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004308"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM01356"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OBZ86257.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="782" mass="90018" checksum="5CFFDC41B6A1E701" modified="2016-11-30" version="1">MARLQNYLSSEFLASGLSLEFNDFITKITKAKSKTEETSHVTEELQRLSARMGLPDVTSSKMKDYLIRLVHCYMLGYNVDFSMIYAIMATQSGETAIERRVGYLACILFLGHEHELSIMLINTLQRDLKSQNYLDQCAALNAICYLEHSELLDNVLDLVIQLSDFPKQIVRKKAVLALCFLYKKTDLDFERIEPVLRGALEDKDTSVVYAALSVWKLVLMENISQYQDLISTFFRIHRQIIEKRIHKSFTYHGVLAPWAQLDCLNIYRLYLQFNTELSNDIYSIVTDCLKSMEKKVDSAFAIVLECIKILSCMDTAFLKSKEATCFRDILDPYLTASNHNIKYLGLVGMSYIDTDLWDLSWLDGILLCKIICSSCKDITIITQAIENLDKIMCIDVLRTISSILADTLNRNYEVQSCNTALAYWLINRVVEHKADDAWFIETMMTLIAETRKNLNDDYVERQCNILKEMLDEETDTNLLREASVNASYQLLKKTNSDTLSPLFVQFVFWTLGENGYLSREYNNIDIMKQLQKWVLLVQGKASMTRKKKGGKPTCLDKILKEFRKSLVPEKQEVSREILLLIQDTSFEKELHDMHVTDMQASLKMSENPNRPTKARKYVANDDHYENQAYSSLSLPSSSASSSHLNELKNLTPTESYTQSTKKNKHDLVSSLIELELNDNVQMTTEQFGALWLQYSVEKKLRFECSIVNCEKLARKLIKSWRIVVIQVIGQEFIAIEATTNTTQSNPDVLIHVALLEQQQLELTLRAKQSDDPISRFLKQRHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NBR1</accession>
    <name>A0A1C7NBR1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Methylenetetrahydrofolate dehydrogenase [NAD(+)]</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">mtd1_1</name>
        <name evidence="2" type="ORF">A0J61_07167</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000469">
        <property type="protein sequence ID" value="OBZ84784.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NBR1"/>
    <dbReference type="STRING" id="101091.A0A1C7NBR1"/>
    <dbReference type="InParanoid" id="A0A1C7NBR1"/>
    <dbReference type="OrthoDB" id="41403at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004487">
        <property type="term" value="F:methylenetetrahydrofolate dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004488">
        <property type="term" value="F:methylenetetrahydrofolate dehydrogenase (NADP+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009113">
        <property type="term" value="P:purine nucleobase biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10860">
        <property type="entry name" value="Leucine Dehydrogenase, chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046346">
        <property type="entry name" value="Aminoacid_DH-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020630">
        <property type="entry name" value="THF_DH/CycHdrlase_cat_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48099">
        <property type="entry name" value="C-1-TETRAHYDROFOLATE SYNTHASE, CYTOPLASMIC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48099:SF3">
        <property type="entry name" value="METHYLENETETRAHYDROFOLATE DEHYDROGENASE [NAD(+)]"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00763">
        <property type="entry name" value="THF_DHG_CYH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53223">
        <property type="entry name" value="Aminoacid dehydrogenase-like, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tetrahydrofolate dehydrogenase/cyclohydrolase catalytic" evidence="1">
        <location>
            <begin position="7"/>
            <end position="114"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ84784.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="277" mass="30838" checksum="D0C4DE71D2B5F30D" modified="2016-11-30" version="1">MTVCKTISASKIASPFRKHVKNVILKERIKPKLVGLLANNDPGACKYAEWTSKVCKETGIDFELRKIDKHSINDHIEKANMDQQINGIMVYYPVFGHEVDNQLQNKISPLKDVEGLGQILEYTGKYNTRLPYCERLKGTNVAIVNRSKIAGSPLAAILANEGANVFSVDINDIQVFQKPDDRNHCSVRNTQLKYDQAISSSDIVITGVPSSDFKLSSALLKPGVTAINFSMNSNFDSDVKSKAGCYVPSIGQVTVAMLVRNALRLYHYQRKQMDLTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NBZ4</accession>
    <name>A0A1C7NBZ4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Putative mitochondrial-processing peptidase subunit beta</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">qcr1</name>
        <name evidence="5" type="ORF">A0J61_05325</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000284">
        <property type="protein sequence ID" value="OBZ86623.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NBZ4"/>
    <dbReference type="STRING" id="101091.A0A1C7NBZ4"/>
    <dbReference type="InParanoid" id="A0A1C7NBZ4"/>
    <dbReference type="OrthoDB" id="10251424at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009060">
        <property type="term" value="P:aerobic respiration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006627">
        <property type="term" value="P:protein processing involved in protein targeting to mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.830.10:FF:000001">
        <property type="entry name" value="Mitochondrial-processing peptidase subunit beta, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.830.10">
        <property type="entry name" value="Metalloenzyme, LuxS/M16 peptidase-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011249">
        <property type="entry name" value="Metalloenz_LuxS/M16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050361">
        <property type="entry name" value="MPP/UQCRC_Complex"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011765">
        <property type="entry name" value="Pept_M16_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007863">
        <property type="entry name" value="Peptidase_M16_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11851:SF126">
        <property type="entry name" value="CYTOCHROME B-C1 COMPLEX SUBUNIT 1, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11851">
        <property type="entry name" value="METALLOPROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00675">
        <property type="entry name" value="Peptidase_M16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05193">
        <property type="entry name" value="Peptidase_M16_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63411">
        <property type="entry name" value="LuxS/MPP-like metallohydrolase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase M16 N-terminal" evidence="3">
        <location>
            <begin position="45"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M16 C-terminal" evidence="4">
        <location>
            <begin position="188"/>
            <end position="369"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00675"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF05193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OBZ86623.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="455" mass="49021" checksum="E348180DFCE0EE74" modified="2016-11-30" version="1">MASRFLSNTLQANSSLTKQFVRPMATAAKQATGSRITNLPNGLTVATEENPSAGVATVGVWVGAGSRNEPASANGVANVLEHIALKGQAAKFEKIGGILNAETQRETTSFAAKTLKANIGASVEILADLLNTNIDTAALNNVRADVLKQQEALASDYETVVFDHLHATAFQGEALGRPVVGVKETVESLTAEDIINFKKQHYGADRIVLVGSGDVDHDELVRLAEQKFGSLSAVGQAQQKKTTFTGSEIRLRDDTLPEAHIALAVEGAPYLSKEYFDLLVMQAIIGAWDKNLGAAANLSSRLSTVVNEHHLANSFASFTKGYKDTGLWGMFVATSNKNQIDDFVHFLQKEWNRLSTSVTASEVERAKQQVKAGLLLSNDSTCQVASTIGSQVLASGKHFTADELKSSVNKVSVDDIRKTAYKLLWDQEIAVVGHGPIEALTDYTRVRGNMAYNRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NC87</accession>
    <name>A0A1C7NC87_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Cell wall integrity protein scw1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">scw1</name>
        <name evidence="5" type="ORF">A0J61_05213</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000276">
        <property type="protein sequence ID" value="OBZ86737.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NC87"/>
    <dbReference type="STRING" id="101091.A0A1C7NC87"/>
    <dbReference type="InParanoid" id="A0A1C7NC87"/>
    <dbReference type="OrthoDB" id="431169at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10501">
        <property type="entry name" value="U1 SMALL NUCLEAR RIBONUCLEOPROTEIN A/U2 SMALL NUCLEAR RIBONUCLEOPROTEIN B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="4">
        <location>
            <begin position="61"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="4">
        <location>
            <begin position="285"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="36"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="39"/>
            <end position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OBZ86737.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="387" mass="44101" checksum="ABA24CEF26B35391" modified="2016-11-30" version="1">MVHINRSNIYQDQDNQSFLDRYCYYPSHKLQPPLLFDQSSVSSPSSSSPSSPPLSAEDEITTIFAVGFPDDMHEREFTNMFSFAKGFLACSLKWHRKEQSDMVYSANKHQMIGFARFNTRKEAHEAIHILNNRKIGNEKGYVLKAEMAKKNLHIKPTVMPSESKSLPNLAAAIPFDSYYQDEDYYRQPPMSRKTSQLSIFSLSPIENNAKQIEPFLPIPSDYSSIEESISGINKTPFFHLPYHLNETKMKTDAFTLFQAPLPDSETNLKPIQAGKKTIDQNPPCNTLYVGNLSANTNMEEIRKLFSACNGYKRMNFRQKLQGPMCFIEFEDVLFAIQAMHQYQGYRLSNSTKAGIRLSFSKNPLFIKSSAPSSSPLASSVKTIFQHY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NCA1</accession>
    <name>A0A1C7NCA1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Nucleoporin NSP1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">NSP1</name>
        <name evidence="3" type="ORF">A0J61_05341</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000285">
        <property type="protein sequence ID" value="OBZ86610.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NCA1"/>
    <dbReference type="STRING" id="101091.A0A1C7NCA1"/>
    <dbReference type="InParanoid" id="A0A1C7NCA1"/>
    <dbReference type="OrthoDB" id="2538017at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.1350">
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="536"/>
            <end position="563"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="45"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="68"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="88"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="133"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="149"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="183"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="203"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="213"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="239"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="276"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="331"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="371"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ86610.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="606" mass="65131" checksum="55986A0A34FABFE9" modified="2016-11-30" version="1" fragment="single">KKRQLDSGDNDNGRSDEGNQAKKPFSFGSQSSDKPATFSFGKPSATDSNKESGSTFKFSAAADKPSFSFGTPATTTADKPAFSFGTPAATSDKPSFSFGTPAATSDKPSFSFGTPATTAPAKKRQLEGSDNNDNGRSEEGNQAKKPFSFGSSSDKSATFSFGKTDDKSDTSKPFTFGSPVTTTEKKKEGEEIKSAPVFTFGSVDKKKEDSTSTKETTPSTKPLSSFSFGAPPKTNKDVTSSTPATTTDTTTSSANKDDTTKSAATTTKMPTFSFGKPEKGKEKETTKIDTTNSTDKEKPTSDKAPSLFSAPKDDAASKPTSGKHVTFNLPSSTTTSSTSTTSATTSTTAPAKGSADIAFSKTGSSDEPSSNDKSTTTKASTTSRATLDLRPVETTGTSTSTPAYQTTLKSTITEPQQITYKTRFWELPDNARNELAIFAHFMSEQTDKQERIAEQLKSSFGPTLSQIHTNTLALNTDAITLRESLEAQSESLDELILQNKKRRLNAVSAGKVQEQDVKSWRSLGAKENWNFFADTVSEMEHRVSSLSRQIDRIDEAIVGLQNQTKFSPESIGRTITKQRQILVSLAGKVAQIHEEADRLIKRRKLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NCN4</accession>
    <name>A0A1C7NCN4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Multidrug resistance protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">ABCB1_2</name>
        <name evidence="13" type="ORF">A0J61_05601</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ABC transporter superfamily. ABCB family. Multidrug resistance exporter (TC 3.A.1.201) subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000307">
        <property type="protein sequence ID" value="OBZ86346.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="FunCoup" id="A0A1C7NCN4">
        <property type="interactions" value="20"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NCN4"/>
    <dbReference type="InParanoid" id="A0A1C7NCN4"/>
    <dbReference type="OrthoDB" id="6500128at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015421">
        <property type="term" value="F:ABC-type oligopeptide transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090374">
        <property type="term" value="P:oligopeptide export from mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd18577">
        <property type="entry name" value="ABC_6TM_Pgp_ABCB1_D1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18578">
        <property type="entry name" value="ABC_6TM_Pgp_ABCB1_D2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03249">
        <property type="entry name" value="ABC_MTABC3_MDL1_MDL2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000205">
        <property type="entry name" value="ABC transporter B family member 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000916">
        <property type="entry name" value="ABC transporter B family member 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="entry name" value="ABC transporter type 1, transmembrane domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039421">
        <property type="entry name" value="Type_1_exporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43394">
        <property type="entry name" value="ATP-DEPENDENT PERMEASE MDL1, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43394:SF27">
        <property type="entry name" value="ATP-DEPENDENT TRANSLOCASE ABCB1-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="ABC transporter transmembrane region"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="70"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="117"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="193"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="220"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="296"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="331"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="742"/>
            <end position="764"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="790"/>
            <end position="813"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="868"/>
            <end position="885"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="891"/>
            <end position="910"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="12">
        <location>
            <begin position="73"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="11">
        <location>
            <begin position="395"/>
            <end position="633"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="12">
        <location>
            <begin position="747"/>
            <end position="1036"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="11">
        <location>
            <begin position="1072"/>
            <end position="1314"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007577"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="OBZ86346.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="1320" mass="144903" checksum="3068CA250BEEC225" modified="2016-11-30" version="1">MKEKHTEIDEKSTNPSASTLEEAPEAITKAPSQPLDEALKPTSKEKSKKKKGESVPLLQLFRFATVKERFMILAALFFSIAAGALMPCSILIYGQYISSITKTLNNTSSLLDSTLPVIHIMAYLGTASLVSGYASNCLWVLTGESQTRRIRSYYLHSVLKQDMSWFDKAADGSLNTRLASDTQIIQDGISEKFGLFVTLIAQFIAGLVVAFVRGWKMACVMLAIIPLLLGSARFMAYFIAKYTIAAQHSYAKGGTVAEQAFQSIRTVYAFTLQKRFLKRYEDRVEEASQFGIRRGIAMGAGFAVFMFILFCSYGLSLWYGSGLVIQGELDGSSVFVVFIAMMIGTMSFIRLPPNLAAVSSAKGAAFKVFQIIDRVPEIDPDSKDGLVLNDFKGSIEFKNVNFKYPTRPDIMILKDLNLQITPGKTVAFVGPSGSGKSTTVQLVQRFYDALSGQVILDGHDIKDLNVRWLRSQIGVVSQEPVLFNMTVRQNLLLGTHDMDISEKAIVAACKEANCHTFITQLPNGYDTIVGEMGGMLSGGQKQRIAIARAILKNPTILLLDEATSALDTQSERLVQNALDKASVTRTTIVVAHRLSTIMKADIIVVLDRGVIIEKGTHQELIDLDGTYADLVRKQAVDVNENGVSEDVKDKEYDADELLRQEEIAVKQQIADQEKLMLTKSITNNSGKSVAISMGSSKIIDGGANETVDAYDLKIAQQKEVKKMIKKQNAPFKKVFMHMRPEWKYLGVGLFGSAIAGCIFPLYAYSFSHVVTILNVPGQDIRPSPLGGTNLYSFIFVMLGIAAFIGNGTQFAAYEICGEKYTKRLRTEVFNAYLKQEVGFFDAEENNAGALTTRLAVDARNVCEMITKVWGDLTSLCATIICSFAIAFSNSWALTLIVLCMAPFLAAATSYEFKIQRGFEDETKKANAESGQVAGEAIREVRTVASLGQQAYFEDRYYHATDRPHRLATRKAYLSSIAAGFGKSINIYTSALAFYAGARLIQNGTITFQQMFTSMTVIMTASESAGRSTTFASSFSKAKFAAIASFGVLERESKIDPDLEGFEPATESVKGDVXYKNITFTYPARPDIPIFNGNFNLQGRAGQTIALVGPSGCGKSTTIGMMQRWYDPAKGTVALDDHNVKSYSVYNLRQHQALVSQEPVLFDLSIGDNIRFGIDDSKQVTQQDIEDACKAANIHSFISGLPDGYDTRVGDKGSQLSGGQKQRIAIARALIRKPKVLLLDEATSALDSESERLVQEALDNILQEGGRTTITIAHRLSTIKNADLICVVKDGRVVEQGTHWELLKLNGAYSEMVNQQSLAIH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7ND52</accession>
    <name>A0A1C7ND52_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">protein-tyrosine-phosphatase</fullName>
            <ecNumber evidence="2">3.1.3.48</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">dusp22b</name>
        <name evidence="7" type="ORF">A0J61_04917</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.48" evidence="2"/>
    <dbReference type="EMBL" id="LUGH01000252">
        <property type="protein sequence ID" value="OBZ87037.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7ND52"/>
    <dbReference type="STRING" id="101091.A0A1C7ND52"/>
    <dbReference type="InParanoid" id="A0A1C7ND52"/>
    <dbReference type="OrthoDB" id="2017893at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004725">
        <property type="term" value="F:protein tyrosine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043409">
        <property type="term" value="P:negative regulation of MAPK cascade"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd14498">
        <property type="entry name" value="DSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.190.10">
        <property type="entry name" value="Protein tyrosine phosphatase superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000340">
        <property type="entry name" value="Dual-sp_phosphatase_cat-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029021">
        <property type="entry name" value="Prot-tyrosine_phosphatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016130">
        <property type="entry name" value="Tyr_Pase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000387">
        <property type="entry name" value="Tyr_Pase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020422">
        <property type="entry name" value="TYR_PHOSPHATASE_DUAL_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10159">
        <property type="entry name" value="DUAL SPECIFICITY PROTEIN PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10159:SF521">
        <property type="entry name" value="LEUCINE RICH REPEAT AND PHOSPHATASE DOMAIN CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00782">
        <property type="entry name" value="DSPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00195">
        <property type="entry name" value="DSPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52799">
        <property type="entry name" value="(Phosphotyrosine protein) phosphatases II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00383">
        <property type="entry name" value="TYR_PHOSPHATASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50056">
        <property type="entry name" value="TYR_PHOSPHATASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50054">
        <property type="entry name" value="TYR_PHOSPHATASE_DUAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0904">Protein phosphatase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tyrosine-protein phosphatase" evidence="5">
        <location>
            <begin position="33"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="domain" description="Tyrosine specific protein phosphatases" evidence="6">
        <location>
            <begin position="96"/>
            <end position="154"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008601"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013064"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OBZ87037.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="204" mass="22996" checksum="C652916704A4F660" modified="2016-11-30" version="1">MPAEDSVEQPESNLYQILECGADGKPGGILITSLGQEVYPHIWLGGYKALESQHFLEKNHIKHILSLGHFKQLYTPGQYCQKIVPVTDHPEADIIQYFPQVIQFIQDALDKGESILVHCLAGVSRSPTVVAAYLMATQKLRWKEALAMIKRTRPFVNPNPGFVAQLKLFQTMGYLFDLNHPAYLDYKKQHPVDAGHVGHSEYNV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-06-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7ND75</accession>
    <name>A0A1C7ND75_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_05442</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000293">
        <property type="protein sequence ID" value="OBZ86516.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7ND75"/>
    <dbReference type="InParanoid" id="A0A1C7ND75"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ86516.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="60" mass="6839" checksum="99AD9127C1130C9A" modified="2016-11-30" version="1">MSVESELNLKLRATVTDKEALYNISCDIEATIGFEDFETQVPYCDIPYMFFKIPLVVISS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NDG6</accession>
    <name>A0A1C7NDG6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Protein PNS1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">ctl1</name>
        <name evidence="7" type="ORF">A0J61_04806</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Probably involved in transport through the plasma membrane.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cell membrane</location>
            <topology evidence="6">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the CTL (choline transporter-like) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000243">
        <property type="protein sequence ID" value="OBZ87142.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NDG6"/>
    <dbReference type="FunCoup" id="A0A1C7NDG6">
        <property type="interactions" value="39"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NDG6"/>
    <dbReference type="InParanoid" id="A0A1C7NDG6"/>
    <dbReference type="OrthoDB" id="420519at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007603">
        <property type="entry name" value="Choline_transptr-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12385">
        <property type="entry name" value="CHOLINE TRANSPORTER-LIKE (SLC FAMILY 44)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12385:SF88">
        <property type="entry name" value="CHOLINE TRANSPORTER-LIKE PROTEIN CTL1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04515">
        <property type="entry name" value="Choline_transpo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="126"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="169"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="197"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="239"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="286"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="320"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="384"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="509"/>
            <end position="526"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007168"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU368066"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OBZ87142.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="585" mass="65302" checksum="5B32CAAD0CAB5214" modified="2016-11-30" version="1">MEQSIPNLARDALSNLKNSFLFQKRGGYYAHMDQESEEEDTHSLFYSVHQNDISQGDSIPLTLSNAYSDRSQLLFDQEQDGLKPSAIYLDEPIGHSNTSLSDSLLPTSATIPVGISQMDKKYKDPIFAVLYIICFGIFFISGIILSLTTNSHAIEEYVKGSTFKTIKDSAGILTIIIATALIMGSLWLFILRTFTKLLVWGTVVCMPIALTVLFIWTLVESFHSYFIYSDQGQTTVRDTGLTIISFIPLLLNLIYMKLVLDHRHRITKTVSVIELACDVARYNPGIILVSMVLLVTFILFSILWLVFFNRLWLVGHLDQGTTWIIHQYVYSLAAFYVFMYIWTAKLLIYMERFCLSVMTAQWYFHRNEPSTANQIPWIASLVQASSTSLGTLALGSLILAIIQCLQLIAKSIRKYAKSARPLATVFSFILSYIDAIISTFSNYTISLAAITGENFFSAANSATKIFRRNLLTGLFGDLLTQLILYIGASVIALSSGLGAYVYATHQLHSPHGFIMGLLGTLMPWYLSQFFSYTMTSIIDASFNTNTTHESCVSIDASFLCYAIDLDTGTVHLSAAHAAFSGLETI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NDU5</accession>
    <name>A0A1C7NDU5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_04674</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000233">
        <property type="protein sequence ID" value="OBZ87273.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NDU5"/>
    <dbReference type="InParanoid" id="A0A1C7NDU5"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="30"/>
            <end position="69"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ87273.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="69" mass="8091" checksum="164E06C083042C7C" modified="2016-11-30" version="1">MAPEAPSDRSPLFLEVEKRLMDTLRDIVMQEREKENEEEDEKDSNEILSKMNKKCKQDKNEEGLALSNH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NE68</accession>
    <name>A0A1C7NE68_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Putative vacuolar amino acid transporter YPQ3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">RTC2_0</name>
        <name evidence="8" type="ORF">A0J61_04548</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>L-histidine(out) + L-arginine(in) = L-histidine(in) + L-arginine(out)</text>
            <dbReference type="Rhea" id="RHEA:71063"/>
            <dbReference type="ChEBI" id="CHEBI:32682"/>
            <dbReference type="ChEBI" id="CHEBI:57595"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the laat-1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000225">
        <property type="protein sequence ID" value="OBZ87402.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NE68"/>
    <dbReference type="InParanoid" id="A0A1C7NE68"/>
    <dbReference type="OrthoDB" id="8048523at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098852">
        <property type="term" value="C:lytic vacuole membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015174">
        <property type="term" value="F:basic amino acid transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034486">
        <property type="term" value="P:vacuolar transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1280.290:FF:000009">
        <property type="entry name" value="PQ loop repeat family protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.290">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051415">
        <property type="entry name" value="LAAT-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006603">
        <property type="entry name" value="PQ-loop_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16201:SF44">
        <property type="entry name" value="SEVEN TRANSMEMBRANE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16201">
        <property type="entry name" value="SEVEN TRANSMEMBRANE PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04193">
        <property type="entry name" value="PQ-loop"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00679">
        <property type="entry name" value="CTNS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="27"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="67"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="94"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="220"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="257"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="288"/>
            <end position="312"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038039"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00050768"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OBZ87402.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="323" mass="36802" checksum="1AC61AFF4817AC00" modified="2016-11-30" version="1">METVCPVLENGSTAIGWIYNIFGDCVYGFQESFSLLFGYLSIFCWLNAQMPQVIKNYRRRDAEGLSFTFLTVWLTGDVANFIGCIITGQLPFQLYLSIYYTIIDTVLCFQWLYYVKYTDNRIRRWFDGDDEVKPAAVISQDNNGNSHLIGERIYTTYSTGGGKEINEQSSLLGSSPQPKKYITMMLFFGFLTFNGLADNSNLLTTESIMLTADHHDENKAIWVGRFFAWLCTFLYLSSRLPQIYQNFSRRSVEGLSMALFFFAAMGNLTYVLSIFTNPHATRAKMLEAVPYIIGSAGTLMFDATIFCQYALFKNRPLTEESTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NEA3</accession>
    <name>A0A1C7NEA3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative glutamine amidotransferase DUG3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">DUG3</name>
        <name evidence="3" type="ORF">A0J61_04530</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000224">
        <property type="protein sequence ID" value="OBZ87421.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NEA3"/>
    <dbReference type="STRING" id="101091.A0A1C7NEA3"/>
    <dbReference type="InParanoid" id="A0A1C7NEA3"/>
    <dbReference type="OrthoDB" id="14446at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061672">
        <property type="term" value="C:glutathione hydrolase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036374">
        <property type="term" value="F:glutathione hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006751">
        <property type="term" value="P:glutathione catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd01908">
        <property type="entry name" value="YafJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.20.10:FF:000060">
        <property type="entry name" value="Related to DUG3-probable glutamine amidotransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.10">
        <property type="entry name" value="Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026869">
        <property type="entry name" value="EgtC-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052373">
        <property type="entry name" value="Gamma-glu_amide_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017932">
        <property type="entry name" value="GATase_2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43187">
        <property type="entry name" value="GLUTAMINE AMIDOTRANSFERASE DUG3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43187:SF1">
        <property type="entry name" value="GLUTAMINE AMIDOTRANSFERASE DUG3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13230">
        <property type="entry name" value="GATase_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="N-terminal nucleophile aminohydrolases (Ntn hydrolases)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51278">
        <property type="entry name" value="GATASE_TYPE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glutamine amidotransferase type-2" evidence="2">
        <location>
            <begin position="2"/>
            <end position="292"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ87421.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="331" mass="37729" checksum="8E3FA9DC0F9B2A65" modified="2016-11-30" version="1">MCRFLLYKGKQPILLAHLVTRPKHSIVNQAFDSKLRLDTRRPLNGDGFGIGWYDNDPQDEITTPCIFTSVTPAWSNINLVRLAEKIRSPLVFAHVRASTSGSVSETNCHPWSYGRLMWMHNGGIAEFDKIKRKLQSSLPEELFLFVEGNTDSEWAFALFLSFLSNPKANSFEHQELKEAMLKTVAQLNVWAEEHNITEPSLLNFAVTDGETVVCIRYISSKTEEAASLYFSSGTRFECYRPGHYRMVKADRREDIVVVASEPLTFEKADWLTIPTNNILVVTPKLNVLLQPIKDRYYTPERGIEIKLNNEDIAIIPEPNAQLYKKSVSLEC</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NEF6</accession>
    <name>A0A1C7NEF6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_04464</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000219">
        <property type="protein sequence ID" value="OBZ87482.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NEF6"/>
    <dbReference type="InParanoid" id="A0A1C7NEF6"/>
    <dbReference type="OrthoDB" id="2230209at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="56"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="97"/>
            <end position="117"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ87482.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="147" mass="17564" checksum="648FEEB517CF9897" modified="2016-11-30" version="1">MLMLERRHAWGILVWEFTNQLDSKDNEDRNDKRSKRRRKRKEGLGRLWELGSFRLFVFRVWCLLGTGSFWALVYIGLAKWDGYAFKYLFQIHHVIQLLLVSTIGGLMMVAFWSFWTFQYKGVLWQKELRKGIVVWYSEGVAYAAEMA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NEY0</accession>
    <name>A0A1C7NEY0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Kinetochore protein mis13</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">mis13</name>
        <name evidence="2" type="ORF">A0J61_04269</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000205">
        <property type="protein sequence ID" value="OBZ87683.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NEY0"/>
    <dbReference type="STRING" id="101091.A0A1C7NEY0"/>
    <dbReference type="InParanoid" id="A0A1C7NEY0"/>
    <dbReference type="OrthoDB" id="3364649at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000444">
        <property type="term" value="C:MIS12/MIND type complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007059">
        <property type="term" value="P:chromosome segregation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013218">
        <property type="entry name" value="Dsn1/Mis13"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14778">
        <property type="entry name" value="KINETOCHORE-ASSOCIATED PROTEIN DSN1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14778:SF2">
        <property type="entry name" value="KINETOCHORE-ASSOCIATED PROTEIN DSN1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08202">
        <property type="entry name" value="MIS13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="184"/>
            <end position="225"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ87683.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="366" mass="42256" checksum="6FF6C7A16DB94FCA" modified="2016-11-30" version="1">MVILTDSTNQPFIVDSQTGIAFKRRAIPAAIPATNLTDSIPATTPEHSAFHHISLGQALSVDDSVSHYSSVDWSDSSQASSVPLRVLAPPEDAPFSEYYKYLPHNFTRAQKMKQLLIWVGQKVVREEQSEPVVNMSREELEIHTLKNSLMQKTIKAIMDDDVEISGYKRPDNSNYSQERPNPINQENERKLTTLEQTVQLLQNEIDEWKENTDQLYEQHAALIDQQNDAEPEEDQLIDLDTFDFEQFAEELEDIEQREFVRQFSQKQKEKSVLKSDAFRQMTEELDLGVANIRQTLNQVDQFLAETDADVSHEMTRLAKEQRERSRYIPIIQDKQVLGAFENTEERRKQSENKTVADILRFIARRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NF92</accession>
    <name>A0A1C7NF92_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_04173</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000198">
        <property type="protein sequence ID" value="OBZ87772.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NF92"/>
    <dbReference type="STRING" id="101091.A0A1C7NF92"/>
    <dbReference type="InParanoid" id="A0A1C7NF92"/>
    <dbReference type="OrthoDB" id="2103474at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025187">
        <property type="entry name" value="DUF4112"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35519">
        <property type="entry name" value="MEMBRANE PROTEINS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35519:SF2">
        <property type="entry name" value="PH DOMAIN PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13430">
        <property type="entry name" value="DUF4112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="196"/>
            <end position="254"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ87772.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="254" mass="28699" checksum="820F46B77BE965B2" modified="2016-11-30" version="1">MQAAATNYAKKKVLGEASSRIHKNKPNFETNPEVLAAAQEAASKKKRHWYGRKVAVTPELILSERDRQLLHKVKSRAWYLDKGFHCCCFNIGLDGMVGLIPGVGDFIGVALALQLVRTACKADLPKWLIGKMMTNIMIDFMLGLTPIAGDILDILFKCNWRNAMLFEEYLFTRRMDEIRVEKGLDVTLNEDRLVTVNDGEPSSAESELTPHKSNKLALHHHDNAPNPNMPEPNTSEDDASKSKNKYGTFFRWKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-06-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NFZ3</accession>
    <name>A0A1C7NFZ3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_04474</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000220">
        <property type="protein sequence ID" value="OBZ87476.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NFZ3"/>
    <dbReference type="InParanoid" id="A0A1C7NFZ3"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="67"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ87476.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="131" mass="15135" checksum="6526D6F8658C91A5" modified="2016-11-30" version="1" fragment="single">RGYGGDGHGRGHHGGKDKRGYDDDWDYDYYKRGYGGGGHGRGHHGGKDKRGYDDDYDYDYDYYKRGYGGDGHGRGHHGGKDKRGYDDDWDYKKGYDDHDGYGKDKRGYHDDWDYKKGYGGHYGKHKGGWHH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NGH7</accession>
    <name>A0A1C7NGH7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 11">UDP-N-acetylglucosamine transferase subunit ALG14</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10 11">Asparagine-linked glycosylation protein 14</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="primary">alg14</name>
        <name evidence="11" type="synonym">ALG14</name>
        <name evidence="12" type="ORF">A0J61_03819</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Involved in protein N-glycosylation. Essential for the second step of the dolichol-linked oligosaccharide pathway. Anchors the catalytic subunit ALG13 to the ER.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4 11">Heterodimer with ALG13 to form a functional enzyme.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 11">Endoplasmic reticulum membrane</location>
            <topology evidence="1 11">Single-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Nucleus membrane</location>
            <topology evidence="2">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 11">Belongs to the ALG14 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000173">
        <property type="protein sequence ID" value="OBZ88128.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NGH7"/>
    <dbReference type="FunCoup" id="A0A1C7NGH7">
        <property type="interactions" value="150"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NGH7"/>
    <dbReference type="InParanoid" id="A0A1C7NGH7"/>
    <dbReference type="OrthoDB" id="17098at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031965">
        <property type="term" value="C:nuclear membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043541">
        <property type="term" value="C:UDP-N-acetylglucosamine transferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004577">
        <property type="term" value="F:N-acetylglucosaminyldiphosphodolichol N-acetylglucosaminyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006488">
        <property type="term" value="P:dolichol-linked oligosaccharide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2000">
        <property type="entry name" value="Glycogen Phosphorylase B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013969">
        <property type="entry name" value="Oligosacch_biosynth_Alg14"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12154">
        <property type="entry name" value="GLYCOSYL TRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12154:SF4">
        <property type="entry name" value="UDP-N-ACETYLGLUCOSAMINE TRANSFERASE SUBUNIT ALG14 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08660">
        <property type="entry name" value="Alg14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 11" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="12" id="KW-0808">Transferase</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004590"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009731"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00017467"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00032062"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU362127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="OBZ88128.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="181" mass="20559" checksum="71454ED40590DFF9" modified="2016-11-30" version="1">MVNALLSKTKGSDAMLGGHTAEMLQLVNSLNPTQYTPRTYVVAHSDLLSEEKARQFEQHVQKGEFKLVKMARARHVGQSWLTVPFSVIKGLFSSVQILISSWPDVIICNGPGSCIPICILSYLPRIFLVKKMEIIYIESFARVYNLSLTGKLLYPFVDRFLVQWPELSNRLQRAEYRGILV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NGP5</accession>
    <name>A0A1C7NGP5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_04014</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000187">
        <property type="protein sequence ID" value="OBZ87929.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NGP5"/>
    <dbReference type="InParanoid" id="A0A1C7NGP5"/>
    <dbReference type="OrthoDB" id="2216037at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ87929.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="188" mass="22581" checksum="841BD1051C866712" modified="2016-11-30" version="1">MGFTVSEKKDIDHATRKTSLERYNVTCAEKHIFCCRKWLKPFKPTYELEWQEHQWLQLDATTSQHIERMRTRGFSRMLIRNDRYLRQHVRYSNPHEFDVLLELSFDIQPASNSQKIRLESNCQHRFMLRRVFWWRSKYGVGEAYLPESVDKSQCCSHALMNQRTSLDKANFFPSLEYITPPNILDNTN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NHH6</accession>
    <name>A0A1C7NHH6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Ribosomal RNA-processing protein 42</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">EXOSC7</name>
        <name evidence="9" type="ORF">A0J61_03491</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
            <location evidence="2">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the RNase PH family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000151">
        <property type="protein sequence ID" value="OBZ88468.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NHH6"/>
    <dbReference type="FunCoup" id="A0A1C7NHH6">
        <property type="interactions" value="74"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NHH6"/>
    <dbReference type="InParanoid" id="A0A1C7NHH6"/>
    <dbReference type="OrthoDB" id="272245at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000177">
        <property type="term" value="C:cytoplasmic exosome (RNase complex)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000176">
        <property type="term" value="C:nuclear exosome (RNase complex)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035925">
        <property type="term" value="F:mRNA 3'-UTR AU-rich region binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000467">
        <property type="term" value="P:exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071028">
        <property type="term" value="P:nuclear mRNA surveillance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071035">
        <property type="term" value="P:nuclear polyadenylation-dependent rRNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016075">
        <property type="term" value="P:rRNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071038">
        <property type="term" value="P:TRAMP-dependent tRNA surveillance pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034473">
        <property type="term" value="P:U1 snRNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034475">
        <property type="term" value="P:U4 snRNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034476">
        <property type="term" value="P:U5 snRNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd11367">
        <property type="entry name" value="RNase_PH_RRP42"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.70">
        <property type="entry name" value="GHMP Kinase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001247">
        <property type="entry name" value="ExoRNase_PH_dom1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015847">
        <property type="entry name" value="ExoRNase_PH_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036345">
        <property type="entry name" value="ExoRNase_PH_dom2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050590">
        <property type="entry name" value="Exosome_comp_Rrp42_subfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027408">
        <property type="entry name" value="PNPase/RNase_PH_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_Su5_D2-typ_SF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11097:SF8">
        <property type="entry name" value="EXOSOME COMPLEX COMPONENT RRP42"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11097">
        <property type="entry name" value="EXOSOME COMPLEX EXONUCLEASE RIBOSOMAL RNA PROCESSING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01138">
        <property type="entry name" value="RNase_PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03725">
        <property type="entry name" value="RNase_PH_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55666">
        <property type="entry name" value="Ribonuclease PH domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="Ribosomal protein S5 domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0271">Exosome</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Exoribonuclease phosphorolytic" evidence="7">
        <location>
            <begin position="31"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="domain" description="Exoribonuclease phosphorolytic" evidence="8">
        <location>
            <begin position="199"/>
            <end position="262"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006678"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00042523"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01138"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF03725"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OBZ88468.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="303" mass="32928" checksum="0C81A0160019869B" modified="2016-11-30" version="1">MPAPLISPAERSYIEQGVEQDCRADGRKRLEYRHIVMESGLLSQASGSARCRLGDSDVLVGIKVEIGEVEQSKPNQGRVICNVECSPSASQQFEGRGADEINNTLTLAIDRIFNGTQSGIDLESLCIIPGQQCWIIYIDAMVMDAAGNLLDCIAMTTRAALHNTRIPKTEVEDLGDGDFEFEVMDDVEDAEPIKGWDNSPISVTLYKVASRYIIDPTVLEELCSQATLTVGVNKDGLVCSVRKGLSGSIDPSLLNEMIGTATALAKPLIEKIDAKLLQDEEAVQDKKRKGEHVEALGFFAAVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NI40</accession>
    <name>A0A1C7NI40_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_03760</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000169">
        <property type="protein sequence ID" value="OBZ88186.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NI40"/>
    <dbReference type="InParanoid" id="A0A1C7NI40"/>
    <dbReference type="OrthoDB" id="5386199at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031966">
        <property type="term" value="C:mitochondrial membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033615">
        <property type="term" value="P:mitochondrial proton-transporting ATP synthase complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009724">
        <property type="entry name" value="TMEM70"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13281">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 70, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13281:SF0">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 70, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="45"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="79"/>
            <end position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ88186.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="216" mass="24443" checksum="098F8542A6D31FA0" modified="2016-11-30" version="1">MSHVQRIIRIISLKRAYSTVSEASSEKKLVYTSPQIGLVKFVKRFSLSTLGISSISTPAIMYFWDSAAAQTMDVSNTMFLGAMMASVCSTGALSFLLSPYVNSIHLHMQHRQNSERQPPISPNTIISIETLDLLARKRTSTLQLKDLLPIANSSLLTWNVNKKALEKQYLLEQMKGIEPKIKQHRFWLDQRNGMGDKDVMSSILRVVQEQGRKKMI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NI61</accession>
    <name>A0A1C7NI61_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">40S ribosomal protein S24</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">RPS24_2</name>
        <name evidence="7" type="ORF">A0J61_03147</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the eukaryotic ribosomal protein eS24 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000130">
        <property type="protein sequence ID" value="OBZ88807.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NI61"/>
    <dbReference type="FunCoup" id="A0A1C7NI61">
        <property type="interactions" value="586"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NI61"/>
    <dbReference type="InParanoid" id="A0A1C7NI61"/>
    <dbReference type="OrthoDB" id="5571754at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.3370:FF:000001">
        <property type="entry name" value="40S ribosomal protein S24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.3370">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00545">
        <property type="entry name" value="Ribosomal_eS24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053709">
        <property type="entry name" value="eRP_eS24_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001976">
        <property type="entry name" value="Ribosomal_eS24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018098">
        <property type="entry name" value="Ribosomal_eS24_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012678">
        <property type="entry name" value="Ribosomal_uL23/eL15/eS24_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10496">
        <property type="entry name" value="40S RIBOSOMAL PROTEIN S24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01282">
        <property type="entry name" value="Ribosomal_S24e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54189">
        <property type="entry name" value="Ribosomal proteins S24e, L23 and L15e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00529">
        <property type="entry name" value="RIBOSOMAL_S24E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 7" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="97"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="103"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009680"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU004381"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU004383"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OBZ88807.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="130" mass="14889" checksum="489D1C55A12FD86E" modified="2016-11-30" version="1" fragment="single">ADASTVTIRTRKFLTNRLLQRKQMVVDVIHPGLPNVSKDELRAKIGKMYKAEKDVVSVFGFKTHFGGGKTTGFALIYDNVEALKKFEPKHRLVRIGLAEAPKGGRKQRKEKKNREKKFRGVRKSKKPRKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-06-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NIT4</accession>
    <name>A0A1C7NIT4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_02957</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000119">
        <property type="protein sequence ID" value="OBZ89003.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NIT4"/>
    <dbReference type="InParanoid" id="A0A1C7NIT4"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ89003.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="75" mass="8544" checksum="1E0709B04C0EF659" modified="2016-11-30" version="1">MIDTLPTLNNGGVSTRSNKNDIKTPYLASNWIETKDILQAYGEPFIANTTPMPFKVLEHGLRYRQVKQLARSYIC</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NIX3</accession>
    <name>A0A1C7NIX3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_02863</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000114">
        <property type="protein sequence ID" value="OBZ89082.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NIX3"/>
    <dbReference type="InParanoid" id="A0A1C7NIX3"/>
    <dbReference type="OrthoDB" id="10497600at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ89082.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="82" mass="9784" checksum="020643FDDFE23124" modified="2016-11-30" version="1">MESCFVSEEHNVEKAMNKFADKFVTHLKQNYNNTNKFREDLNKWLAIRGILKLNKHIDTDLTDVFCSRKMEVLYESFIKEVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NJJ8</accession>
    <name>A0A1C7NJJ8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_02798</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000110">
        <property type="protein sequence ID" value="OBZ89158.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NJJ8"/>
    <dbReference type="InParanoid" id="A0A1C7NJJ8"/>
    <dbReference type="OrthoDB" id="2288107at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ89158.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="493" mass="56846" checksum="A6B3C964E15135BF" modified="2016-11-30" version="1">MSSYSNFKFPNESNPQINPFFSKFPFSEWNIDNFQNYNNTEDASADFLYNIRKIKESNVPKEVKSGLGRIITSLKGKRKADTDAQLIVKFNNSNVSQLNINSVVHNHANVNQIIEQVKKRKINHVKESPSWQVEDDGDVWEAWRQYLDTCECHDFCLEKYHIVECGYSIQCNPNVPEDLYAVVDTSNYTVTSAFLACTRYTSSVLNTMKTDDIDAIENAVKCQQDDKTMDPVCFEYTKHFFKTCLWLYRKKGLYKRLAINESSFNHLLVWPIMELAVDEIDDEELAFVTAEYVLKSSAEEYKADGCILFGEDELCLLETSGKFMLEDNSKYGYDHIKMTFGALCLFNAIYKKYCWANEDTALKLKIPFVHSRGNMLHLWSLELCSTKLYSSKKVYKSLVPEKLSNTKDIVTLGNFVWLLKNEVQHAVNIVKTMKQEHEQYELDNLLAQNDSRQSSLSNLVDNDIQKPCKGAGYGILLPKEKNADEIDLKHKIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NK67</accession>
    <name>A0A1C7NK67_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">A0J61_02427</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000091">
        <property type="protein sequence ID" value="OBZ89527.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NK67"/>
    <dbReference type="InParanoid" id="A0A1C7NK67"/>
    <dbReference type="OrthoDB" id="10017054at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005856">
        <property type="term" value="C:cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008017">
        <property type="term" value="F:microtubule binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.418.10">
        <property type="entry name" value="Calponin-like domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.920.20">
        <property type="entry name" value="Gas2-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001715">
        <property type="entry name" value="CH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036872">
        <property type="entry name" value="CH_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003108">
        <property type="entry name" value="GAR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036534">
        <property type="entry name" value="GAR_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11915">
        <property type="entry name" value="SPECTRIN/FILAMIN RELATED CYTOSKELETAL PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00307">
        <property type="entry name" value="CH"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02187">
        <property type="entry name" value="GAS2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00033">
        <property type="entry name" value="CH"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00243">
        <property type="entry name" value="GAS2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47576">
        <property type="entry name" value="Calponin-homology domain, CH-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143575">
        <property type="entry name" value="GAS2 domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50021">
        <property type="entry name" value="CH"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51460">
        <property type="entry name" value="GAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Calponin-homology (CH)" evidence="6">
        <location>
            <begin position="57"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="domain" description="Calponin-homology (CH)" evidence="6">
        <location>
            <begin position="201"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="domain" description="GAR" evidence="7">
        <location>
            <begin position="2809"/>
            <end position="2883"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="985"/>
            <end position="1031"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="2689"/>
            <end position="2708"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="2750"/>
            <end position="2806"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="2916"/>
            <end position="2962"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="1504"/>
            <end position="1566"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="2494"/>
            <end position="2521"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="2570"/>
            <end position="2607"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="987"/>
            <end position="1004"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="1012"/>
            <end position="1029"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="2766"/>
            <end position="2777"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="2933"/>
            <end position="2955"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50021"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OBZ89527.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="3000" mass="342869" checksum="0A21A9B15033B1B6" modified="2016-11-30" version="1">MDHMLSPTPQQDNRSISTSHKRTASSSSHLIPPVTTHRKQSIDDDELNKNISLEYQDIQIRTLTKWMNVQLNQVGDHINSIDKDLKDGKKLLKLLSVVADQPQLKPERGHMLIHELSNVSRALKFLQEQWGIDSLPAIASEAIVSGDVKSTLALAFFIMLKYQIHPILLNSSNDQVDPKLPPPSPLPTLSTSRLNGAKPLAEAKSALLYWVRSQLEDYVANQIIYTIQDFSRSWRSGLAFCLLIHRHDPELLPTLFTEHIPHIKNKETWSTVLNLAFDVAEKSMHIPQYLEPADLLIEYPHEPSVMMYVSEVYKVMSRQAYETAEHRQKRLQDIALIAPQIVSTEPHSSTPQEDTTVEHQLDLLDSLIKDPNAPIEQIHRLLIDIPTQLPAEYQTRFNQLREDWEKRTQPQIDPFLLKLREIMPKDDHHELLHPLDGTIEMADQFEQSLTLLTHEYHQSNPDHDAYVLSILEATSDTCLQFRHGVMFGQITSAINDELDVIQKLMADRESSTVTDELIQSLEERIHLVSATIQGVRDEYEGRLLTADKNGLFTARFIERMEQLEDRYQIVRDWVDQVRVWFVEAERIRAWIDHHIQIIEERNRQSESIEPTSHDIPVPEQHVIELHEAHERLKQEIDHFDSDDMDRLRAHVKMLTHSSEKELTPADTSTIEITLTTLNRLSHLTKLLENRSHWIRLLLLRVKWENAFGLSVQWIAQTDHELNEFLSTARWSEKEEENYRSRLLDAEEQEIEEPSAHGVEEIINRLVQLEQKIVDFDRGAYSEVLEAYQEMEGLTSLPDYLEARQLGFEKAFEDLMKRSGFSRKIVEQLLSMISTVEKFKELRDVGEQLRHELLRSSSSSSRQSLEEEDIYAERAQAFKEESARLITNASTCIPYPAAPEMSTAMGAHDAHDNEVTNESIRSAISSYSMSLALIADGLDQLLMSRYQDMSLQQRASEAFEAMVRFKVWMDERIRLLKKPRFDTMLYKSSPSTSSSSTSSSSSMSHSSEDNTHSPRGNISPHTSTNTTMNTLPMDDESLLRLEKERDGIASRLDQMEQDELARLFDSVRALEHDIDASNAVSIDRSALINGLESLQESHQELKDLVSLRGIQLDALKHRLQWENQWAKSNIHLQTIARKLCDFNIKKARYDPAKENVEKPSYDNDHDIIQSLQFLQDRATELGERHLSGLDESFQELVSSYNKLPSHHLNGNLTVIVGVPDFISNRQSDLRIKYDDLRLLTSYTSDLVSQRSSLTEFLMRSLDARHEGEKIKELVSKRTRRIMATEDEETLGLDTRVAEFKQEIKQIWEDCGKNMPYPVYNGNWLKSSSGDTNNNNNSNSAYRAQVRSQIKSLIDKKMEDLYALEKEIDQCLASYRDADRIKALVNQYEQEACELGRWIHEQIELLRRQHIDVSAESFLARGMNISDLKKARLEMCMQTETFETDKVRLLHDRIAQLVQESVEKKKHRSIDISQAARQLGEVMEHLSQLKRGLSDQAITLEAASMRDQWEKDLQKGIAKLEEMNEQLRKFNAKKNALIAQDELHEEDVVALQQELNKLVSQKNKFEKHIMPSIQLSYDAFVEYFPKLSRPMATPDHLEARMESLGRTASRFQESVEARSKELELIKQRMRWEDIVKQAFRFLAGKEALMEAFVDEKARWHDDAPIDSDEDEETKLRTEWSDIYNDIKQYEENQIASIEKCYERLVSDSNDHYSNTSTTLLPTVVTKKMQDLKLSQERANYFLSFSNEVITQRCLVSAFILRTAQLEQSAELIREEFIATKVGSAQIVGLFENHTERLEKFKASIDDVRLNLANSIPFPVRSLEGGSTQAKIKDETTNSVIHEAIRLRNTRLEELWSSLQQILESKERVSRRRLTLHAYDKQVALVRDWIDTRRGILEQSHLAEDNTDVDKAKEAVREADSVEKSMQSNDTVMSSLIAAFDKCVAAFEDNSLNAEDADENNTALTDKLDTFVKPTQDQLTQAWQQLLSDVMEANKDRTARLIQLKINCWLDSLNSLSLRIEEESKEAAVSNDQLALWMDEIDQLENKEYQALLADITSKSYDQSLLEPGRVKMEAIRTQLHDLQNELHLSQLIQKYMLDITRLEDMMNDQMGCLDRVHEEHSVVADEATSEHRDHQHQALVSKYKHASDVMIDIKDTLSDVSSQYEAIVSQTPNYPNSYAKLNDTWHHLMNKESSVSALVARSSKWIKQYNLLTSVQRSLETIQSELTQHSPEAYPKISDELSRMETVLHEDLDNLDDDLLADTININAFNTRKTVSVDLSIKLRQLLQQQLSEKETAELIASIQHVIDRLLDICQQQLAVAAKHSESCILNENEADMETIITSCSDIISATDAIYNQSQNELDSVRTQEGEKLVTQLEYPQEQLNALFAPITTKLAELDSFTKSEQEYIAITKLMLEYVQSKTSLLTSMDACMTKLNEGKDSEEIVYELEAQSGSFDESAEDMYKLGDAAKNYRVTHLMHVEARTKPISPIIDEGNAAVSQSLSQLKQALMEAKESIDQHHHLQRLITKLHDALQLVADTRERVNSFKLTNKRIASEARELEELCNDYHEVIDKKTKAIDSLMRSHAEAEQLRQELAEAMRQLDVLIDAKKSEVCQEDDLSGFMNIIHTAEQHIASLQTAIDNASPHLSGIVNNRFVKTDLQNLLKSLVTAFKHHQQMINKVFEEARAELSKQGSDEEASQKLQKTTKRWNHTKAAAAARERELQTCISQLDHEFFTKLAIAKAGPHTKTLYPASPPSVTPKKHIAPISSNSKTHNLSVNRREEPSYRRPSKTPVSASSSSSRIRTTYVPDPENELDMKLGHIVNTSPYRVTVKSIPDQVGKYWFGDVNPRLVYCRILASQLVMVRVGGGWVELSKFLRDHGLNEGAYSRPDSANDNSTSSSQDAGPFQEAFLQTVRSSSPSGRVTIRGGGGADRSSNSLASTRSSSRSSGGSRSKSPMPGYVDGKNYISIDELGNHIIVKMKKADDHAKTPIINKKKLLQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NKI6</accession>
    <name>A0A1C7NKI6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Selenoprotein O</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">A0J61_02301</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SELO family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000085">
        <property type="protein sequence ID" value="OBZ89647.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NKI6"/>
    <dbReference type="FunCoup" id="A0A1C7NKI6">
        <property type="interactions" value="72"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NKI6"/>
    <dbReference type="InParanoid" id="A0A1C7NKI6"/>
    <dbReference type="OrthoDB" id="10254721at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070733">
        <property type="term" value="F:AMPylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045454">
        <property type="term" value="P:cell redox homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00692">
        <property type="entry name" value="SelO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003846">
        <property type="entry name" value="SelO"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF000658">
        <property type="entry name" value="PRK00029.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32057">
        <property type="entry name" value="PROTEIN ADENYLYLTRANSFERASE SELO, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32057:SF14">
        <property type="entry name" value="PROTEIN ADENYLYLTRANSFERASE SELO, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02696">
        <property type="entry name" value="SelO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00031547"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OBZ89647.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="590" mass="67496" checksum="6699A5EB1E4033AA" modified="2016-11-30" version="1">MNIRAMATRTLESLPSVPTKFTKSLPCDIYTANITETAKTNLMRTPRPVHNAVYSHVYPEHAPDPQLLAVSKPALQQIGLDEEVTKTEEFVSVFSGNKTLPDTCPWSLCYAGHQFGFFAGQLGDGRAISLFETINQQGESWEIQLKGAGRTPYSRFGDGYAVLRSSIREFLMSEHMHALGIPTTRALALIETSRDVFREDGPRGSQPETGAIVARMAPSWLRFGNFEIFYSRDDMDNVKRLADYTIEHVVKDDHHPEVGNQYARLFRTVTEKTAQMVAEWQAIGFNHGVMNTDNMSVLGLTMDYGPFQIMDYYNPFYVCNHSDEAGRYAFHRQPSAAMFNLVKFSVPLFELIGAGEEVDSVVFPDKDNELKEGVTDEETLERYRDAGKMFVQTLLNTDFKNYFMVHLIKKMRSKIGLVGTTTDDSQSDMDDVIIPLLDWMTAYHVDYHRFYRSLSNYQITSAGEEADADQAIQQWLDIVTEESEELATCKESLKPWLSIYRHRLLKDKLDHTERKRQMDAVNPRFVLRNSIAEEVIQAFEDEDEEEAKSRLDACLYACLHPFEQHYEDERIERWISNPIPAKDMRCSCSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NKM5</accession>
    <name>A0A1C7NKM5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">ATP-dependent 6-phosphofructokinase</fullName>
            <shortName evidence="14">ATP-PFK</shortName>
            <shortName evidence="14">Phosphofructokinase</shortName>
            <ecNumber evidence="14">2.7.1.11</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="14">Phosphohexokinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="17" type="primary">pfk1_0</name>
        <name evidence="17" type="ORF">A0J61_02273</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="14">Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13 14 15">
            <text>beta-D-fructose 6-phosphate + ATP = beta-D-fructose 1,6-bisphosphate + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:16109"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:32966"/>
            <dbReference type="ChEBI" id="CHEBI:57634"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.11"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 14">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="activity regulation">
        <text evidence="14">Allosterically activated by ADP, AMP, or fructose 2,6-bisphosphate, and allosterically inhibited by ATP or citrate.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3 14 15">Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose: step 3/4.</text>
    </comment>
    <comment type="subunit">
        <text evidence="14">Homotetramer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 14">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="15">Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade "E" sub-subfamily.</text>
    </comment>
    <comment type="similarity">
        <text evidence="14">Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.11" evidence="14"/>
    <dbReference type="EMBL" id="LUGH01000083">
        <property type="protein sequence ID" value="OBZ89682.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NKM5"/>
    <dbReference type="FunCoup" id="A0A1C7NKM5">
        <property type="interactions" value="349"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NKM5"/>
    <dbReference type="InParanoid" id="A0A1C7NKM5"/>
    <dbReference type="OrthoDB" id="537915at2759"/>
    <dbReference type="UniPathway" id="UPA00109">
        <property type="reaction ID" value="UER00182"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005945">
        <property type="term" value="C:6-phosphofructokinase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003872">
        <property type="term" value="F:6-phosphofructokinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016208">
        <property type="term" value="F:AMP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070095">
        <property type="term" value="F:fructose-6-phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042802">
        <property type="term" value="F:identical protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048029">
        <property type="term" value="F:monosaccharide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061621">
        <property type="term" value="P:canonical glycolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030388">
        <property type="term" value="P:fructose 1,6-bisphosphate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006002">
        <property type="term" value="P:fructose 6-phosphate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.460:FF:000007">
        <property type="entry name" value="ATP-dependent 6-phosphofructokinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.460:FF:000008">
        <property type="entry name" value="ATP-dependent 6-phosphofructokinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.450">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.180.10">
        <property type="entry name" value="2,3-Dihydroxybiphenyl 1,2-Dioxygenase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.460">
        <property type="entry name" value="Phosphofructokinase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03184">
        <property type="entry name" value="Phosphofructokinase_I_E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009161">
        <property type="entry name" value="6-Pfructokinase_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022953">
        <property type="entry name" value="ATP_PFK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029068">
        <property type="entry name" value="Glyas_Bleomycin-R_OHBP_Dase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015912">
        <property type="entry name" value="Phosphofructokinase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000023">
        <property type="entry name" value="Phosphofructokinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035966">
        <property type="entry name" value="PKF_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02478">
        <property type="entry name" value="6PF1K_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13697:SF4">
        <property type="entry name" value="ATP-DEPENDENT 6-PHOSPHOFRUCTOKINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13697">
        <property type="entry name" value="PHOSPHOFRUCTOKINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00365">
        <property type="entry name" value="PFK"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000533">
        <property type="entry name" value="ATP_PFK_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00476">
        <property type="entry name" value="PHFRCTKINASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54593">
        <property type="entry name" value="Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53784">
        <property type="entry name" value="Phosphofructokinase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00433">
        <property type="entry name" value="PHOSPHOFRUCTOKINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 14" id="KW-0021">Allosteric enzyme</keyword>
    <keyword evidence="10 14 15" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 14" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="12 14 15" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="9 14 15" id="KW-0418">Kinase</keyword>
    <keyword evidence="11 14" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7 14" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8 14 15" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 14 15" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Phosphofructokinase" evidence="16">
        <location>
            <begin position="163"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="domain" description="Phosphofructokinase" evidence="16">
        <location>
            <begin position="552"/>
            <end position="843"/>
        </location>
    </feature>
    <feature type="region of interest" description="N-terminal catalytic PFK domain 1" evidence="14">
        <location>
            <begin position="1"/>
            <end position="537"/>
        </location>
    </feature>
    <feature type="region of interest" description="Interdomain linker" evidence="14">
        <location>
            <begin position="538"/>
            <end position="551"/>
        </location>
    </feature>
    <feature type="region of interest" description="C-terminal regulatory PFK domain 2" evidence="14">
        <location>
            <begin position="552"/>
            <end position="926"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="14">
        <location>
            <position position="312"/>
        </location>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="171"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <begin position="234"/>
            <end position="235"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <begin position="264"/>
            <end position="267"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="265"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" description="in other chain" evidence="14">
        <location>
            <begin position="310"/>
            <end position="312"/>
        </location>
        <ligand>
            <name>substrate</name>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="347"/>
        </location>
        <ligand>
            <name>substrate</name>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" description="in other chain" evidence="14">
        <location>
            <begin position="354"/>
            <end position="356"/>
        </location>
        <ligand>
            <name>substrate</name>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" description="in other chain" evidence="14">
        <location>
            <position position="411"/>
        </location>
        <ligand>
            <name>substrate</name>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="439"/>
        </location>
        <ligand>
            <name>substrate</name>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" description="in other chain" evidence="14">
        <location>
            <begin position="445"/>
            <end position="448"/>
        </location>
        <ligand>
            <name>substrate</name>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" description="in other chain" evidence="14">
        <location>
            <position position="621"/>
        </location>
        <ligand>
            <name>beta-D-fructose 2,6-bisphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58579"/>
            <note>allosteric activator; ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" description="in other chain" evidence="14">
        <location>
            <begin position="680"/>
            <end position="684"/>
        </location>
        <ligand>
            <name>beta-D-fructose 2,6-bisphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58579"/>
            <note>allosteric activator; ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="718"/>
        </location>
        <ligand>
            <name>beta-D-fructose 2,6-bisphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58579"/>
            <note>allosteric activator; ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" description="in other chain" evidence="14">
        <location>
            <begin position="725"/>
            <end position="727"/>
        </location>
        <ligand>
            <name>beta-D-fructose 2,6-bisphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58579"/>
            <note>allosteric activator; ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" description="in other chain" evidence="14">
        <location>
            <position position="785"/>
        </location>
        <ligand>
            <name>beta-D-fructose 2,6-bisphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58579"/>
            <note>allosteric activator; ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="811"/>
        </location>
        <ligand>
            <name>beta-D-fructose 2,6-bisphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58579"/>
            <note>allosteric activator; ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" description="in other chain" evidence="14">
        <location>
            <begin position="817"/>
            <end position="820"/>
        </location>
        <ligand>
            <name>beta-D-fructose 2,6-bisphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58579"/>
            <note>allosteric activator; ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" description="in other chain" evidence="14">
        <location>
            <position position="899"/>
        </location>
        <ligand>
            <name>beta-D-fructose 2,6-bisphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58579"/>
            <note>allosteric activator; ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00048070"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PIRNR" id="PIRNR000533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF00365"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="OBZ89682.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="926" mass="100496" checksum="565677EA25A0D877" modified="2016-11-30" version="1">MSAQGLSHIIFNASNLKDYENTLKFYHALGFEQVVDKSENITNQSESRTAWLRLNAGADYASDATIKLVLNALAKSQSKPSKDLDWSAQENAIVLAVKDINAVKSKLNKLEFTVQEYSSGDGARVFVLDPLNNVIAFTNQSCLKATSAAAAVEKAADGSKRKKIAVLTSGGDAPGMNAVVRAVVRYGISKGCDIFAVYEGYQGLVDGGELLKKMDWKSVRGWLAVGGTTIGTARCMPFKTREGRLQAAENLVKNGIDSLIVCGGDGSLTGADLFRSEWPSLIEELNNTKRISDEEAVTYKFLTIVGLVGSIDNDMSSTDITIGAVTSLHRICEAVDAVSTTALSHSRAFVIEVMGRHCGWLALMAGIATGADFVFIPEKPPQEEDWESVMCSVIERHRSLGKRKTVVIVAEGAIDKNLNAIKADHLKDILTNRLGLDTRVTILGHTQRGGAPAFFDRLLATAQSIEAVDAVLESTPETPSPMIGWIKNKVTRFPLMQAVKLTHEVAEAIGQKNFKRAMELRDPQFAEEYDAYNATTILDDNSIGLPDHQKLRIGIIHVGAPAGGMNAATRTAVRYCLNRGHTPIAIHNGFAGLSRGVTDILSWLSVDGWTALGGSELGTNRAVPGEDIDMGMIAYQMQKQNIQGLLIVGGFEAFVALQRLEEAREKYPSLRVPITLIPATISNNVPGTDYSLGSDTSLNAIVNSCDAIVQSAQSSRRRVFMVEVMGGRSGYLAVEAGLAVGAVTVYIPEEGINLARLQSDVSHLRAMYHDDDLDKSEGRIILRTEDVSSTYTNDVISNILKDEGNEMFDSRTAVLGHIQQGITPSPLDRIRATRLAIRSIEFIEKHALPALEKAHKEGSAIPIELTNAEESITVAGISDHSVVFEPVSALLANTDMKNRKPRSAWWYEHRPIIDLLAGRGVFQPPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-06-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NLA1</accession>
    <name>A0A1C7NLA1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_03881</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000177">
        <property type="protein sequence ID" value="OBZ88074.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NLA1"/>
    <dbReference type="InParanoid" id="A0A1C7NLA1"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ88074.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="66" mass="7438" checksum="BCC3FA4C78707761" modified="2016-11-30" version="1">MMHLDLHNNNLSHALDQPALILLDRVDEPGGRLLCSSPVLTFGLGWEGPWHQSARYPTDRAHHRCA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NLN6</accession>
    <name>A0A1C7NLN6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Transmembrane and coiled-coil domain-containing protein 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">TMCO3</name>
        <name evidence="13" type="ORF">A0J61_01916</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000067">
        <property type="protein sequence ID" value="OBZ90017.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NLN6"/>
    <dbReference type="InParanoid" id="A0A1C7NLN6"/>
    <dbReference type="OrthoDB" id="1654420at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015386">
        <property type="term" value="F:potassium:proton antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1530.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006153">
        <property type="entry name" value="Cation/H_exchanger_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045158">
        <property type="entry name" value="KEA4/5/6-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038770">
        <property type="entry name" value="Na+/solute_symporter_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16254">
        <property type="entry name" value="POTASSIUM/PROTON ANTIPORTER-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16254:SF14">
        <property type="entry name" value="TRANSMEMBRANE AND COILED-COIL DOMAIN-CONTAINING PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00999">
        <property type="entry name" value="Na_H_Exchanger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0050">Antiport</keyword>
    <keyword evidence="9" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-0406">Ion transport</keyword>
    <keyword evidence="8 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <keyword evidence="4 11 13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="210"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="259"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="283"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="316"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="344"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="371"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="419"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="472"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="495"/>
            <end position="519"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="526"/>
            <end position="545"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="557"/>
            <end position="576"/>
        </location>
    </feature>
    <feature type="domain" description="Cation/H+ exchanger transmembrane" evidence="12">
        <location>
            <begin position="215"/>
            <end position="577"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="584"/>
            <end position="605"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="9">
        <location>
            <begin position="130"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="13">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022449"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF00999"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="OBZ90017.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="605" mass="67334" checksum="0AE12859B1EAAC85" modified="2016-11-30" version="1" fragment="single">ALVLTNADKIVDMLQKGADHKQELEIKKSQLYQSIEAVHGQERDELYALAGVKLDDFEAFESFVLGILQVYDQTVSQPPFRSSYDFKSPALTLAFEFQKAIKLSHQKYRSVAESVHRFHANQPVDDELMMQVIHTMLKEVSDNADQLENDMKQANMMFSLDDARIETVLKLNQEDEKVASLVDQDNNEYVMMKPFDATVIIEDTQLIHDFILLLITSFVLGWMFTWIGLPAFFGYILAGILAGPSGFNRIKEIIQIETLAQLGVVFIIFVLGLEFSIEKIKKMWQLALGGAMMILMVTVLFFALMGYMIGADVKEAVFVGACISLSSTAVVVKCIRLDQLDHLYGLLVMQDVLLGFMLAIMPALSKSGMQVAFAIIRTAMSFTIFGLVCFLIVHLLPLIPRVVKHAIPIQSIQTNHELMLLGTVAICMSMLILSEYLGLGMELGCFAAGVIIRSRKGMFETSIAVIEPVRDLFASLFFAAIGLHVYPSFLASEVMVLLTLAGGVIGFKYIATCIILYLFRFDLHKSSVMAVALSQISEFGFVLASRAKQLSIISREVYYLLLATTSITLIATPLLLKMTAKSSRHEHPDNHDAISVSLSDTEKLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NMJ8</accession>
    <name>A0A1C7NMJ8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">U11/U12 small nuclear ribonucleoprotein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">Snrnp35</name>
        <name evidence="6" type="ORF">A0J61_01649</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000055">
        <property type="protein sequence ID" value="OBZ90305.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NMJ8"/>
    <dbReference type="STRING" id="101091.A0A1C7NMJ8"/>
    <dbReference type="InParanoid" id="A0A1C7NMJ8"/>
    <dbReference type="OrthoDB" id="6159137at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071011">
        <property type="term" value="C:precatalytic spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017069">
        <property type="term" value="F:snRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.330:FF:000132">
        <property type="entry name" value="Small nuclear ribonucleoprotein U11/U12 subunit 35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051183">
        <property type="entry name" value="U1_U11-U12_snRNP_70-35kDa"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13952">
        <property type="entry name" value="U1 SMALL NUCLEAR RIBONUCLEOPROTEIN 70 KD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13952:SF6">
        <property type="entry name" value="U11_U12 SMALL NUCLEAR RIBONUCLEOPROTEIN 35 KDA PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="5">
        <location>
            <begin position="47"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="142"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="142"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="168"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="195"/>
            <end position="205"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OBZ90305.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="205" mass="23652" checksum="B140AE31DCFB5118" modified="2016-11-30" version="1">MWYSKEYKPVQVGSIDGAGTVPHDAAVKRAAQSTYQPPKNLKTDPQCTLFVGRLSLDTSEASLHSHFEKYGQIKEVRIVRNQVTGISQGYGFVTFTKDKYTKDAYRHANKTTLDHHIILVDYERSRTMKGWIPRRLGGGFGGKKESGQLRFGGRDRPFRDPAQGHIPYDQRHSDDWRYLESKKRRSSSPNESKRYTKRSRYTHIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NML5</accession>
    <name>A0A1C7NML5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Succinate-semialdehyde dehydrogenase</fullName>
            <ecNumber evidence="6">1.2.1.16</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">davD</name>
        <name evidence="8" type="ORF">A0J61_02227</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5 6">
            <text>succinate semialdehyde + NAD(+) + H2O = succinate + NADH + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:13217"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30031"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57706"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.2.1.16"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4 6">
            <text>succinate semialdehyde + NADP(+) + H2O = succinate + NADPH + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:13213"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30031"/>
            <dbReference type="ChEBI" id="CHEBI:57706"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.2.1.16"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 6">Amino-acid degradation; 4-aminobutanoate degradation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the aldehyde dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.2.1.16" evidence="6"/>
    <dbReference type="EMBL" id="LUGH01000081">
        <property type="protein sequence ID" value="OBZ89716.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NML5"/>
    <dbReference type="FunCoup" id="A0A1C7NML5">
        <property type="interactions" value="183"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NML5"/>
    <dbReference type="InParanoid" id="A0A1C7NML5"/>
    <dbReference type="OrthoDB" id="310895at2759"/>
    <dbReference type="UniPathway" id="UPA00733"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004777">
        <property type="term" value="F:succinate-semialdehyde dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036243">
        <property type="term" value="F:succinate-semialdehyde dehydrogenase (NADP+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034599">
        <property type="term" value="P:cellular response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006540">
        <property type="term" value="P:gamma-aminobutyrate shunt"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009450">
        <property type="term" value="P:gamma-aminobutyric acid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd07103">
        <property type="entry name" value="ALDH_F5_SSADH_GabD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.309.10:FF:000004">
        <property type="entry name" value="Succinate-semialdehyde dehydrogenase I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.605.10:FF:000005">
        <property type="entry name" value="Succinate-semialdehyde dehydrogenase I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.605.10">
        <property type="entry name" value="Aldehyde Dehydrogenase, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.309.10">
        <property type="entry name" value="Aldehyde Dehydrogenase, Chain A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016161">
        <property type="entry name" value="Ald_DH/histidinol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016163">
        <property type="entry name" value="Ald_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016162">
        <property type="entry name" value="Ald_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015590">
        <property type="entry name" value="Aldehyde_DH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050740">
        <property type="entry name" value="Aldehyde_DH_Superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010102">
        <property type="entry name" value="Succ_semiAld_DH"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01780">
        <property type="entry name" value="SSADH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43353">
        <property type="entry name" value="SUCCINATE-SEMIALDEHYDE DEHYDROGENASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43353:SF5">
        <property type="entry name" value="SUCCINATE-SEMIALDEHYDE DEHYDROGENASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00171">
        <property type="entry name" value="Aldedh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53720">
        <property type="entry name" value="ALDH-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldehyde dehydrogenase" evidence="7">
        <location>
            <begin position="58"/>
            <end position="517"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009986"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00050387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00052698"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU365091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OBZ89716.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="522" mass="56801" checksum="F3DD9EFB1C45089E" modified="2016-11-30" version="1">MIKSALQNTYLKACLNPSRTTPVKRFAMTSRTIVTSVTVPKLKDQSLFKEAAFINNEWTDKNVTEKFTVYDPATDKEIGKLPDMGAKETKEAIQVASEAFKTWSQTTGKQRHDLLMKWYYAMIENQDDLATILTWENGKTLTEAKGEVTYAASFYEWFAEEAVRAYGTVIPNHLPGQRSIAIKQPVGVVGIITPWNFPAAMITRKVGAALAAGCTVVIKPGAETPYSAFALAELAKRVGIPPGVVNIVPTDKHVAEVGKELCTNPIVKKISFTGSTAVGKLLMSQSAGTMKKVSMELGGNASFIVFDDAELDAAVEGVIACKFRGTGQTCVSANRIYVQKNIYKEFSSRLAEKVSKFQVGHGFDEKTTHGPLINSKGVEKVKRHVEDAVKKGAQVLAGGEHHGGNFYAPTVLGDMTTEMEIHTEETFGPVAALFPFETEDEVISLANDTPFGLANYFFSRDVGRCWRVAERLESGMVGVNAGAVSSCYTPFGGVKESGVGREGSKFGLDDYMNIKYINMAGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NNF6</accession>
    <name>A0A1C7NNF6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_01451</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000046">
        <property type="protein sequence ID" value="OBZ90500.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NNF6"/>
    <dbReference type="InParanoid" id="A0A1C7NNF6"/>
    <dbReference type="OrthoDB" id="2282428at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ90500.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="92" mass="10683" checksum="F1F3E82857FC8994" modified="2016-11-30" version="1">MASLPSPPPSPSNYKKHRRSDSFALIQSIIKEREKEEHQEEEMMIKSRLLRYSCPVNTFEESKDAAEKVIPHKSLSHVRFATEPPKVYHYSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NNL7</accession>
    <name>A0A1C7NNL7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Putative beta-lactamase HcpC</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">hcpC</name>
        <name evidence="7" type="ORF">A0J61_01893</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the sel-1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000066">
        <property type="protein sequence ID" value="OBZ90056.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NNL7"/>
    <dbReference type="STRING" id="101091.A0A1C7NNL7"/>
    <dbReference type="InParanoid" id="A0A1C7NNL7"/>
    <dbReference type="OrthoDB" id="9922773at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.2220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006597">
        <property type="entry name" value="Sel1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050767">
        <property type="entry name" value="Sel1_AlgK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002893">
        <property type="entry name" value="Znf_MYND"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11102:SF160">
        <property type="entry name" value="ERAD-ASSOCIATED E3 UBIQUITIN-PROTEIN LIGASE COMPONENT HRD3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11102">
        <property type="entry name" value="SEL-1-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08238">
        <property type="entry name" value="Sel1"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01753">
        <property type="entry name" value="zf-MYND"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00671">
        <property type="entry name" value="SEL1"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81901">
        <property type="entry name" value="HCP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144232">
        <property type="entry name" value="HIT/MYND zinc finger-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50865">
        <property type="entry name" value="ZF_MYND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="MYND-type" evidence="6">
        <location>
            <begin position="439"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="480"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00038101"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OBZ90056.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="480" mass="53917" checksum="88EF9DFE477440BE" modified="2016-11-30" version="1" fragment="single">MSIQPHDESTMDPNAGMLEVPAFLGMTEQQSRLLVALYNETDPEFAKQMPTALPIAAQQLAAEYEKRNNVGKKLERANHVWSEEYKLFDTIQREAVEKLSTTDMNIDKAAEGLSLDEDQEASIHDLIMGSLLYGGIRREPSGPDDRASMSPVASPNFEGAKRLLERAFEKGYSMAAVQIGSFFMQEEKLAGGANLKQKTPTAKELAYNWYKKAADASNPMACHKLGFFLENGIGCEKDISKAIEYYTKAYEEGYPDSAHNLGIIYQGFTQETSRFRDIKKAIEYFERAKQWGFSASCNALGRMYLLMSKNADLAKEAGNPGSEPEDYVVTGIELMEDAANNGDADAMMMLGLIFGSKDYGLYDMDKAQNYMELALVRGDLEAYNYLVRILRAKMAARVALEKENFDNFEKLSQADQEKLIRQLAKEAASDNISHRHCAHVDCDKREEEPGSFKRCGRCQRVAYCSRECQKEHWKAGHKAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NPV1</accession>
    <name>A0A1C7NPV1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_00830</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000021">
        <property type="protein sequence ID" value="OBZ91132.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NPV1"/>
    <dbReference type="InParanoid" id="A0A1C7NPV1"/>
    <dbReference type="OrthoDB" id="2288800at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ91132.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="361" mass="42275" checksum="A92C91A2A3A1F0B5" modified="2016-11-30" version="1">MIASSFFTEGIRVHLSDTRIEMLLNDLLKYKSFGPKITKVALSNHSTGQIEPTLFRSTLSLCPNLTEIEFDTNEIYHYLRALNSREALLPSIQEIRITSLELCSPAIRRFHVWLYYRFRMTITTLEITDANTNDALNTYGGLVAFIRLFPNLKHLKAESNTMLRDRSISIDLHALLTNAPQLESLELFFFNMVTSNIRKPQEPTEYSTLKRLKLDVSRAEFNTLDYITTRFKHLHNITFVASRLVPNNALTTSQEQATIDCFLDYCSKIEETKVWFIFRHRQYFKDNTNKCPIHHALWSVEWASEELEFELTSLYNDMLFDEMHDIEDFLDFHDEGYWVSYYPDEDEDGDALAFHYASIHV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NQ79</accession>
    <name>A0A1C7NQ79_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">CCDC174 alpha/beta GRSR domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">A0J61_00758</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000019">
        <property type="protein sequence ID" value="OBZ91188.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NQ79"/>
    <dbReference type="FunCoup" id="A0A1C7NQ79">
        <property type="interactions" value="515"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NQ79"/>
    <dbReference type="InParanoid" id="A0A1C7NQ79"/>
    <dbReference type="OrthoDB" id="333551at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025066">
        <property type="entry name" value="CCDC174-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057464">
        <property type="entry name" value="CCDC174_GRSR"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15885">
        <property type="entry name" value="COILED-COIL DOMAIN-CONTAINING PROTEIN 174"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15885:SF1">
        <property type="entry name" value="COILED-COIL DOMAIN-CONTAINING PROTEIN 174"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25449">
        <property type="entry name" value="CCDC174_GRSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13300">
        <property type="entry name" value="DUF4078"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CCDC174 alpha/beta GRSR" evidence="3">
        <location>
            <begin position="138"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="27"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="242"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="249"/>
            <end position="262"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF25449"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OBZ91188.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="291" mass="34178" checksum="8D09E3CF64027D79" modified="2016-11-30" version="1">MQKPIKNVSSTTAVDLKAELAQHVDQFEKMRSSSGKQVTARRPDKKPTVWSRQNKGVNDRNQRDMQVLPAVESDVLARSREQLEKKARFYEAMQSGQFEYDPEDEDNILVDFDRKYLEEKDAEKKSRKKKRVEEEDPWVEYEDEFGRTRVVRKSQLPQREEEVIEDEIEAPVYDFSKSDRTNMNHFEADREIRTKGVGFYQFSKDEDERQAQMDKLNKIRQETENARKSVVSAASKRKQMMAQNAEKIRARKAALQAKRHHQLKPEQLPDVNPVVNEDSVTNFLKSIRDKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NQE7</accession>
    <name>A0A1C7NQE7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Stomatin-like protein 2, mitochondrial</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">Stoml2</name>
        <name evidence="6" type="ORF">A0J61_00595</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the band 7/mec-2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000014">
        <property type="protein sequence ID" value="OBZ91333.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NQE7"/>
    <dbReference type="FunCoup" id="A0A1C7NQE7">
        <property type="interactions" value="578"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NQE7"/>
    <dbReference type="InParanoid" id="A0A1C7NQE7"/>
    <dbReference type="OrthoDB" id="434619at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007005">
        <property type="term" value="P:mitochondrion organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd08829">
        <property type="entry name" value="SPFH_paraslipin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.479.30:FF:000008">
        <property type="entry name" value="Stomatin-like protein 2, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.479.30">
        <property type="entry name" value="Band 7 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050710">
        <property type="entry name" value="Band7/mec-2_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001107">
        <property type="entry name" value="Band_7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036013">
        <property type="entry name" value="Band_7/SPFH_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032435">
        <property type="entry name" value="STML2-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001972">
        <property type="entry name" value="Stomatin_HflK_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43327">
        <property type="entry name" value="STOMATIN-LIKE PROTEIN 2, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43327:SF10">
        <property type="entry name" value="STOMATIN-LIKE PROTEIN 2, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01145">
        <property type="entry name" value="Band_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16200">
        <property type="entry name" value="Band_7_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00721">
        <property type="entry name" value="STOMATIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00244">
        <property type="entry name" value="PHB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117892">
        <property type="entry name" value="Band 7/SPFH domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Band 7" evidence="5">
        <location>
            <begin position="71"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="361"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="364"/>
            <end position="377"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OBZ91333.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="406" mass="44576" checksum="FE882BE82C46B549" modified="2016-11-30" version="1">MSSLLRSSNLTSKGRLLTAGRILSIKSAPFQRKTVAFYGGYGYNNDYDNSYGSSGGSWGSSSERQSLPRNTIIKFVPQQEAWIVERMGKFHTMLEPGLNILMPFIDRIRYVKSLKETAIEVPSQSAITQDNVTLELDGVLYIRCVDPFKASYGVEDAEFAITQLAQTTMRAEIGQMTLDRTLAERAHLNANIVDAINSAAEDWGIRCLRYEIRDIHPPSKIVESMHQQVSAERTKRAQILESEGARQAAINVAEGRKQATILASEAEKAEKINMAAGEAEAILLRAKASAEGIERVARAIESNHGNDAVSMTVAEKYVEAFGKMAKEGTTMIVPASTNDAASMVTQALAIYNTINNKKTFHQKSSSNSPTSSSLTDSAHLKEAVTDMLEHPDKENISKHINNVSKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NQG2</accession>
    <name>A0A1C7NQG2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Telomerase Cajal body protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">WRAP53</name>
        <name evidence="1" type="ORF">A0J61_01299</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000039">
        <property type="protein sequence ID" value="OBZ90666.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NQG2"/>
    <dbReference type="FunCoup" id="A0A1C7NQG2">
        <property type="interactions" value="569"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NQG2"/>
    <dbReference type="InParanoid" id="A0A1C7NQG2"/>
    <dbReference type="OrthoDB" id="239865at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051150">
        <property type="entry name" value="SWT21/TCAB1_mRNA_Telomere"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13211">
        <property type="entry name" value="TELOMERASE CAJAL BODY PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13211:SF0">
        <property type="entry name" value="TELOMERASE CAJAL BODY PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ90666.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="468" mass="52574" checksum="4E018330CEE803A6" modified="2016-11-30" version="1">MTETETEIHTESYSLFVPDLSQPCHLIGSTADRYNDSVRHCLAKDSHLIQQTVDLEQQSTGNNYFRNAKWSPDGSFLLTNSADDVLRLFQLPQNVYEEQDTGEPVQMAPNLGIREGEAVYDFAWFPTMNAQDPSTCCFITSVRDHPIQLWDACTGSVRASYRAIDHCERFVGPNVLCFNLDGSKIYTGYENMIEIFDTYSGSSDKKPTIPKRKSRHGQKGIISCLDFAPDGYYYAAGSYSASIGIYDAHNDKLSLKLTGIEAGVTQVKFSKDGLYLFSASRHSDTILCWDIRDSANVLYELPRPGRTNQRIQFDLDPSGKYLITGDTQGNLLSYDITTGALEDIETKKRLVSSVSLHQDIISSVSFNPVYPVMSTCSGQRKFSLPSVDSDESEEEEEEIIIDNTLKTWRVPGQYEWYTYEQPLEIADTTDQTALVTDQTAMTIDQTTMVTDQTTMITETTTTIDSQMD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NQI4</accession>
    <name>A0A1C7NQI4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Heat shock factor protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">hsf1_4</name>
        <name evidence="10" type="ORF">A0J61_00786</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the HSF family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000020">
        <property type="protein sequence ID" value="OBZ91169.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NQI4"/>
    <dbReference type="STRING" id="101091.A0A1C7NQI4"/>
    <dbReference type="InParanoid" id="A0A1C7NQI4"/>
    <dbReference type="OrthoDB" id="60033at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.10:FF:000027">
        <property type="entry name" value="Heat shock transcription factor 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000232">
        <property type="entry name" value="HSF_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10015:SF427">
        <property type="entry name" value="HEAT SHOCK FACTOR PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10015">
        <property type="entry name" value="HEAT SHOCK TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00447">
        <property type="entry name" value="HSF_DNA-bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00056">
        <property type="entry name" value="HSFDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00415">
        <property type="entry name" value="HSF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0346">Stress response</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HSF-type DNA-binding" evidence="9">
        <location>
            <begin position="73"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="318"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="493"/>
            <end position="516"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="643"/>
            <end position="662"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="37"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="318"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="336"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="498"/>
            <end position="516"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="649"/>
            <end position="662"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006403"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU004020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00415"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OBZ91169.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="662" mass="74846" checksum="2974B889EFD62630" modified="2016-11-30" version="1">MTGSSRSFNMTPTVQQFSESKSDYTQAVDSEEDMGKRPLKRKRHHQSSPPSLLANHSYPTTMNLPHKMTSQRSVPAFLHKLFKRVTKESFFSYISYSIHSMVGDPSTNQLVRWSKDGNSFLVEGHERFAKHVLPRFYKHNTFASFVRQLNMYDFHKIPHLQQGALVSSSGTENEVWEFSHPHFQRNRPDLLVLVSRKRNRDRDKPNADQMNLGSLVKEITAIRKHQANITADLRNLHHDNEIIWRETLAAREKFQKHQQVISKILQFLSAVFSDDQSMLYELSNQKDFLNINSLQLPDNKGEIKSKFNKFVASHEFSHRSKFDKDSDNQHGNSEKGASSSDSGIGSADSSGNNSSEDDTKPSQVSPKDLKQKLINPKLFSDNTARSAEAITCDINELQENVELLAAQLGIDPLDLTAKSNEVEKFSDNHMNMISSASQDDKMRLFKLASEDDRHVSPHRTLGHPYHLTDNFLVQPGSYPFDSQHPFVQQVLKQEHAPSPTTAETPSNNNNNLSTQQPLVNTNPLPMYVATQSLATGSLSVHQPPLATNSNMTMNHLFDPSFRQRDAEFHHNEPATMNPEFCHTAPIYRNKFGMADYVPYYDASSSTISTPPLLQQHGNNSLHSSTIVPTPQFGMMYPAVHMDASPSSARMKDTVGSKVDQDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MNS2</accession>
    <name>A0A1C7MNS2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transposable element Tcb1 transposase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">TCB1_4</name>
        <name evidence="2" type="ORF">A0J61_11859</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01002595">
        <property type="protein sequence ID" value="OBZ78513.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MNS2"/>
    <dbReference type="STRING" id="101091.A0A1C7MNS2"/>
    <dbReference type="InParanoid" id="A0A1C7MNS2"/>
    <dbReference type="OrthoDB" id="2416077at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038717">
        <property type="entry name" value="Tc1-like_DDE_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052338">
        <property type="entry name" value="Transposase_5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23022:SF135">
        <property type="entry name" value="SI:DKEY-77F5.3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23022">
        <property type="entry name" value="TRANSPOSABLE ELEMENT-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13358">
        <property type="entry name" value="DDE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tc1-like transposase DDE" evidence="1">
        <location>
            <begin position="63"/>
            <end position="202"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13358"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ78513.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="239" mass="27974" checksum="4B06841F64C98DEF" modified="2016-11-30" version="1">MSKYLEREVLQGINTGIFSNAKDAQSLEAVHKPDVLSLTSKRKKDRLNWAKSRQNWTINNWKRVVFSEETKIKRSASNDAQWAWKAVDEELKDFQLKHLYKHGGVSINVWSCFCRRGPGYLTKIEDRMNFNLYIEVLDDELIKTLDYYNYSEDTVIFEQNNDPKHTAKKALKHLEDRGTEVMDCPAYSPDLNPIQNFKRRLAACFTHSDSIHELFSHVTKVWKNIEPTICEEPIECMPD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MNW8</accession>
    <name>A0A1C7MNW8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_11854</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01002590">
        <property type="protein sequence ID" value="OBZ78518.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MNW8"/>
    <dbReference type="STRING" id="101091.A0A1C7MNW8"/>
    <dbReference type="InParanoid" id="A0A1C7MNW8"/>
    <dbReference type="OrthoDB" id="2363016at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="176"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="353"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ78518.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="353" mass="40789" checksum="0C136FB628110DEE" modified="2016-11-30" version="1" fragment="single">YAMGEQYQFYKPIHDDSLVFREDTTNTVGKVQLPTSVLCCHDTLSSSSSSSNTSAVPQRILSVSYLTNPSPSPQLPQIMPRTTEETEPYVRPYMRPLQSPWSPLEDAPSQSIKYPHLNTLINTSPSEVLMEPKQRGFYYQDGRISREPVLLQRYAEQGVLTQANLIKKRKKPFHDPDYPYELPTPVKKPKIPHRHGEFKQRRDDIISRMRTIMMADLEQKAQRLPSDFTLSIEKATLPAHINPDELSPDEASQLLAPALRILTEHSNMKPHLDNGMNQNGIYYNNDYFRLYLAFTQFQEIFAQLFPNEVIKMNLPEDAPSPTSLERDKDRERNANMKAYRGWIEPYLTETNWA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MTN9</accession>
    <name>A0A1C7MTN9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">methylisocitrate lyase</fullName>
            <ecNumber evidence="3">4.1.3.30</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">ICL1_0</name>
        <name evidence="5" type="ORF">A0J61_11710</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>(2S,3R)-3-hydroxybutane-1,2,3-tricarboxylate = pyruvate + succinate</text>
            <dbReference type="Rhea" id="RHEA:16809"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:30031"/>
            <dbReference type="ChEBI" id="CHEBI:57429"/>
            <dbReference type="EC" id="4.1.3.30"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the isocitrate lyase/PEP mutase superfamily. Isocitrate lyase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.1.3.30" evidence="3"/>
    <dbReference type="EMBL" id="LUGH01002373">
        <property type="protein sequence ID" value="OBZ80241.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MTN9"/>
    <dbReference type="STRING" id="101091.A0A1C7MTN9"/>
    <dbReference type="InParanoid" id="A0A1C7MTN9"/>
    <dbReference type="OrthoDB" id="4078635at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004451">
        <property type="term" value="F:isocitrate lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046421">
        <property type="term" value="F:methylisocitrate lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019752">
        <property type="term" value="P:carboxylic acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.60">
        <property type="entry name" value="Phosphoenolpyruvate-binding domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006254">
        <property type="entry name" value="Isocitrate_lyase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015813">
        <property type="entry name" value="Pyrv/PenolPyrv_kinase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040442">
        <property type="entry name" value="Pyrv_kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21631:SF3">
        <property type="entry name" value="BIFUNCTIONAL GLYOXYLATE CYCLE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21631">
        <property type="entry name" value="ISOCITRATE LYASE/MALATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00463">
        <property type="entry name" value="ICL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51621">
        <property type="entry name" value="Phosphoenolpyruvate/pyruvate domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0456">Lyase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="194"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001050"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005704"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012260"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OBZ80241.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="194" mass="21896" checksum="FB1558B5DDAFAE28" modified="2016-11-30" version="1" fragment="single">MTVDYEQKLFLEEVEKVKQWWASPRFANVKRPYTAEAIVSKRGYFPIQYRSDVQAKKVWKLLQNHKANGTTSHTFGALDPVQVTQMAPHLETVYVSGWQCSSTASTSNEPGPDLADYPMDTVPNKVEHLFFAQLFHDRKQREARLAMSPEERAKTPAIDYLRPIIADGDTGHGGITAVMKLAKMFVERGAAGMH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MUG5</accession>
    <name>A0A1C7MUG5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_11554</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01002184">
        <property type="protein sequence ID" value="OBZ80397.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MUG5"/>
    <dbReference type="InParanoid" id="A0A1C7MUG5"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="10"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ80397.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="120" mass="13870" checksum="B40F01CC381116DD" modified="2016-11-30" version="1">MLQEKNVVDFEGEKEEKEEEKEEEKEEEKEEEKEEEEKEDEEELWETDVDEDDDCTVIDATGDDYEVIRSAGKAPKAVAKSTEKASILALASDLIDFYDSLSTKQNKENTIDSIRNLMKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MUL3</accession>
    <name>A0A1C7MUL3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_11825</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01002542">
        <property type="protein sequence ID" value="OBZ80126.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MUL3"/>
    <dbReference type="InParanoid" id="A0A1C7MUL3"/>
    <dbReference type="OrthoDB" id="2230412at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ80126.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="110" mass="13373" checksum="B37621AD380CF186" modified="2016-11-30" version="1" fragment="single">RHRKEDYNPEDILKLMEATIRCLKHAMSRRYLSTSWKTFEKRQVLAVQCVNNTITLMCSKRVEENKGCFIEQRSTIVPRDWSNRFFWVKVMEILLKLKIYWMNRSVSQKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MVT8</accession>
    <name>A0A1C7MVT8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_11011</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001587">
        <property type="protein sequence ID" value="OBZ80940.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MVT8"/>
    <dbReference type="InParanoid" id="A0A1C7MVT8"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ80940.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="62" mass="7326" checksum="055F709F4249B4B6" modified="2016-11-30" version="1" fragment="single">KLWYNLTLTVVAVKSIFTIYFLEVNGFGFRKHQYSFTTFFMRDRIAKPFCSMNSGFINSDLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MW00</accession>
    <name>A0A1C7MW00_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transposon TX1 uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">YTX2_12</name>
        <name evidence="2" type="ORF">A0J61_10958</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001540">
        <property type="protein sequence ID" value="OBZ80993.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MW00"/>
    <dbReference type="InParanoid" id="A0A1C7MW00"/>
    <dbReference type="OrthoDB" id="2443300at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.10.10">
        <property type="entry name" value="Endonuclease/exonuclease/phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036691">
        <property type="entry name" value="Endo/exonu/phosph_ase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005135">
        <property type="entry name" value="Endo/exonuclease/phosphatase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03372">
        <property type="entry name" value="Exo_endo_phos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56219">
        <property type="entry name" value="DNase I-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Endonuclease/exonuclease/phosphatase" evidence="1">
        <location>
            <begin position="21"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="396"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03372"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ80993.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="396" mass="44985" checksum="0AE6825FA1195341" modified="2016-11-30" version="1" fragment="single">MSNRHKLLLNLGSLNCNSLFDILALQETHASPSKQPVLNTQFQAHQTLWTFNCGLVSFSPSFTLSDNLLPQIDRAILSRVHHPHNLFDPFYILVVYAPASSGRDRQQFFSLLLSQLRRPDLALNRDRLFIVGDFNYSYLRGALSSATSNDWLVFLETDFVNTLESSDSHEISTFRRNDTVQSTIDYIFLSKALQSHIMAGEIQLLNPAWTDHSLLSTRCSLGQSPLGSGIWRANPQLLQNPGYLNHLKQALPGLIERSTKDYLRPQDRWDNIKSGLNHHTINFPLIRILEKKETEAASKPTKPPFGIKLRRLPAFDRPIAHIQAKLTDILAMRSNTRWRERGETSVKYLRRAISTRASTQQITALRSNTDSSPSSSIESMLECSEEFYSTLYSADP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MW93</accession>
    <name>A0A1C7MW93_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_10879</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001477">
        <property type="protein sequence ID" value="OBZ81072.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MW93"/>
    <dbReference type="InParanoid" id="A0A1C7MW93"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="20"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="27"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ81072.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="90" mass="9883" checksum="06F40D14611558B0" modified="2016-11-30" version="1">MAMDSWLARAILSSIFWNSKPKKAASKGSTQTASQAGDFNIPSTPPEINVSFMAEDDLGSENQLGQASNFIFEKENKLKKQSNCLEDIKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MWC8</accession>
    <name>A0A1C7MWC8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">pyruvate kinase</fullName>
            <ecNumber evidence="4">2.7.1.40</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="primary">pyk1</name>
        <name evidence="15" type="ORF">A0J61_11223</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="13 17">
            <text>pyruvate + ATP = phosphoenolpyruvate + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:18157"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.40"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 5/5.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the pyruvate kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.40" evidence="4"/>
    <dbReference type="EMBL" id="LUGH01001794">
        <property type="protein sequence ID" value="OBZ80729.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MWC8"/>
    <dbReference type="STRING" id="101091.A0A1C7MWC8"/>
    <dbReference type="InParanoid" id="A0A1C7MWC8"/>
    <dbReference type="OrthoDB" id="108365at2759"/>
    <dbReference type="UniPathway" id="UPA00109">
        <property type="reaction ID" value="UER00188"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030955">
        <property type="term" value="F:potassium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004743">
        <property type="term" value="F:pyruvate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.33.10:FF:000001">
        <property type="entry name" value="Pyruvate kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.60">
        <property type="entry name" value="Phosphoenolpyruvate-binding domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.33.10">
        <property type="entry name" value="PK beta-barrel domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001697">
        <property type="entry name" value="Pyr_Knase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015813">
        <property type="entry name" value="Pyrv/PenolPyrv_kinase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040442">
        <property type="entry name" value="Pyrv_kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011037">
        <property type="entry name" value="Pyrv_Knase-like_insert_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015793">
        <property type="entry name" value="Pyrv_Knase_brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015806">
        <property type="entry name" value="Pyrv_Knase_insert_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11817">
        <property type="entry name" value="PYRUVATE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00224">
        <property type="entry name" value="PK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51621">
        <property type="entry name" value="Phosphoenolpyruvate/pyruvate domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50800">
        <property type="entry name" value="PK beta-barrel domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="11" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="8 15" id="KW-0418">Kinase</keyword>
    <keyword evidence="10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12 15" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Pyruvate kinase barrel" evidence="14">
        <location>
            <begin position="32"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="15">
        <location>
            <position position="219"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004997"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008663"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012142"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00048152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF00224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="OBZ80729.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="219" mass="24199" checksum="B2A89FD35E434A93" modified="2016-11-30" version="1" fragment="single">MFADKKSSFSPIEFPMQWVANMDVDVQPKAARKTSIICTIGPKTNKVEKLTELIDAGMNIVRMNFSHGDYDYHKSVLDNARAAAAARPDKVIAIALDTKGPEIRTGMMANDTEIAITKGHEMNFTTDDKYMNACDAENMYIDYKNLPKVIEVGKAIYVDDGVLSFKVLSKGEDFVRVQAQNNGKLCSKKGVNLPKTAVDLPALSEKDKNDLRFGVENGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MWL3</accession>
    <name>A0A1C7MWL3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Ribosome biogenesis protein WDR12</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">Wdr12</name>
        <name evidence="8" type="ORF">A0J61_10746</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001362">
        <property type="protein sequence ID" value="OBZ81207.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MWL3"/>
    <dbReference type="FunCoup" id="A0A1C7MWL3">
        <property type="interactions" value="449"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7MWL3"/>
    <dbReference type="InParanoid" id="A0A1C7MWL3"/>
    <dbReference type="OrthoDB" id="10251381at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070545">
        <property type="term" value="C:PeBoW complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030687">
        <property type="term" value="C:preribosome, large subunit precursor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051276">
        <property type="term" value="P:chromosome organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0110136">
        <property type="term" value="P:protein-RNA complex remodeling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042273">
        <property type="term" value="P:ribosomal large subunit biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012972">
        <property type="entry name" value="NLE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19855:SF11">
        <property type="entry name" value="RIBOSOME BIOGENESIS PROTEIN WDR12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19855">
        <property type="entry name" value="WD40 REPEAT PROTEIN 12, 37"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08154">
        <property type="entry name" value="NLE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 5" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="NLE" evidence="7">
        <location>
            <begin position="8"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="97"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="186"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="253"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="295"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="220"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="228"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="368"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF08154"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OBZ81207.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="368" mass="40989" checksum="A93C10B26F925371" modified="2016-11-30" version="1" fragment="single">MSSEQEQVQVRFITQQPKYAVNDAPMLLPSNIQKEGLSEIVNSLLDLEKPIPFDFLIEGQLLRTSVVDYLNAARLSTENVITIEYVESMLPPVPLTAYEHDDWISSVHGHQGQLFLTGAYDNMVRLWNSMGECTATLTSHTDAVKSVSFGQVTDSTAQIFSGSLDQSVLGWSVDLNDHTHRVMYECKGHKGAIESISVDQSNRYLATASADSLVKIWTTEEPEEDEPSHETVNKKRKKLTTDERKLKTKAVTLEGHVGGVNAVVFDSGDSNVVFTGGWDHSIRSWDIEQQVNLTTKNCEKVVLDVDYSSKAKLLATGHSDHTVRLWDPRSEEGTNVKMNLRGHTAWVSSVSWSKKSEYTLCTGSYDSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MWN9</accession>
    <name>A0A1C7MWN9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_10720</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001340">
        <property type="protein sequence ID" value="OBZ81230.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MWN9"/>
    <dbReference type="STRING" id="101091.A0A1C7MWN9"/>
    <dbReference type="InParanoid" id="A0A1C7MWN9"/>
    <dbReference type="OrthoDB" id="185373at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050667">
        <property type="entry name" value="PPR-containing_protein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002885">
        <property type="entry name" value="PPR_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47939">
        <property type="entry name" value="MEMBRANE-ASSOCIATED SALT-INDUCIBLE PROTEIN-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47939:SF5">
        <property type="entry name" value="PENTACOTRIPEPTIDE-REPEAT REGION OF PRORP DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13812">
        <property type="entry name" value="PPR_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51375">
        <property type="entry name" value="PPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="repeat" description="PPR" evidence="1">
        <location>
            <begin position="450"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00708"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ81230.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="578" mass="65806" checksum="E17B322466EE5576" modified="2016-11-30" version="1" fragment="single">SLSAYEAVFDVLARQGKHRRIEFWLDQLADKGLDPSLGIVRSVVLSRLGQHQLEEAIGYLKRYPTTLADLVTRYADPDQGRTLLDHALTRFALDCLDQWQLNTARTIYLIKHKLGMNTTAVLNSLMTKAIFTHQTRTAEAILRDTLACRDTAGAHACSKRLIQRYLAKKDLKHAIGVWQQMEQKNIPLLPDVFQLLIQRAAQLKYHVDTLRLYTRYRELYPRMSLEIPVIVLRCMADAREFELAKQVVPEVEPILSKLNRSLARNALLALFKISSQTGEIELFERAFEASEALQLNLTHQGLTSLIACYLQRGEIEAAKAAFHKVATYTDGPDVVDFNLLMRITMLEGTSGIHDKIFEILSHMKLVDVSPDETTLRTMLDFYEDGSEMKNSLLVKLLQVADSRSEHVFANNLALTQFLKTKTVQEAVQLLCQNDRGALFASEKGKPIVRDGITYQILLDAMAGESRYSSMTERLLKDMEARGLKPSRRVYERLIEALAKKKKLSKARRYIAKMKTDFGIQPDLHLYTKLVDNLMLQEVPHLAKEVIKIDMVAERVKPDRNLKNKLKTIESLLSSSRSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MWQ5</accession>
    <name>A0A1C7MWQ5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_10708</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001332">
        <property type="protein sequence ID" value="OBZ81242.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7MWQ5"/>
    <dbReference type="InParanoid" id="A0A1C7MWQ5"/>
    <dbReference type="OrthoDB" id="2282872at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ81242.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="209" mass="22830" checksum="D9F0B1AAD9EB4D64" modified="2016-11-30" version="1">MLGLRGQYKSEGGIVNVPVSVDKTISCVPRSLTDTNTFDAGLTRRLAQSNYYMAGNVRLEKIWAAAHFFGQSAAYMKHNVKIKDSEEEFNQQSTLIAQNHEFKQSVIALSELTIDSDNIADDLENDLTXESNPGGQKTIFVGELTARIVQEDEGVRIAPAEGXSPMSLLLNKDVKSLAFPTLVGGAILDPKHKGALLNYSAIAKFLARH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MWZ1</accession>
    <name>A0A1C7MWZ1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Endonuclease/exonuclease/phosphatase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_10639</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001286">
        <property type="protein sequence ID" value="OBZ81311.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MWZ1"/>
    <dbReference type="STRING" id="101091.A0A1C7MWZ1"/>
    <dbReference type="InParanoid" id="A0A1C7MWZ1"/>
    <dbReference type="OrthoDB" id="2289333at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ81311.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="87" mass="9724" checksum="F3D59A8329D77CB6" modified="2016-11-30" version="1" fragment="single">MGSLNCRSIAKTASTQNRSSFIRHLRSLSFTLLALQETHADNPHVQETLHTQFQASDSIWSAHYGLVCFSPDVMLSDAFISRCGRLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MX02</accession>
    <name>A0A1C7MX02_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">YEATS domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">A0J61_10535</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001223">
        <property type="protein sequence ID" value="OBZ81415.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MX02"/>
    <dbReference type="STRING" id="101091.A0A1C7MX02"/>
    <dbReference type="InParanoid" id="A0A1C7MX02"/>
    <dbReference type="OrthoDB" id="1741717at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000785">
        <property type="term" value="C:chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd16907">
        <property type="entry name" value="YEATS_YEATS2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1970">
        <property type="entry name" value="YEATS domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038704">
        <property type="entry name" value="YEAST_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005033">
        <property type="entry name" value="YEATS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055127">
        <property type="entry name" value="YEATS2_3HBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055129">
        <property type="entry name" value="YEATS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058706">
        <property type="entry name" value="zf-C2H2_AHC1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23195">
        <property type="entry name" value="YEATS DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22951">
        <property type="entry name" value="3HBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03366">
        <property type="entry name" value="YEATS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25909">
        <property type="entry name" value="zf-C2H2_AHC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51037">
        <property type="entry name" value="YEATS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="YEATS" evidence="4">
        <location>
            <begin position="346"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="224"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="479"/>
            <end position="522"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="10"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="225"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="259"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="275"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="498"/>
            <end position="507"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00376"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51037"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OBZ81415.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="861" mass="98413" checksum="13EBBA55ED70AA77" modified="2016-11-30" version="1">MELPSVDPPPADKKTLNSIPRDESTRKKIVEIIDHQFDLEIYLKEREIATIKKEIARAESVLNDIKQAIANETTAASMPESAHYTRRSAMYYHGGSQAFYQQNKMSINPLTKRKVYRTSEKSKLYGRRQDGVFVSLACPVCHRDDFANQQGFLNHCRISHNLEFGPYEQIMIQCGTPVDDAEVPMDHPARLRPVMNLAPVAKQQNKKIERPSIKVFEEDVDMELENEHRKMSNTTDLDRVESEPKSQPTLIQKEEIPQPSETMQETNEAQVQSEPVHDVPEQTIEKDEEEEEKDKPNDPSIETNLPEPIENATAQKQVEEEEEEQTEQPKVESLAAAVSSADTADIGSRFYIKRHIIVGNVSKFIIPERRDPSLKQFTHKWMIYVVEPPQSKESISAFITCVRFYLHPSYKPNDVVDVTEPPFKLTRLGWGEFPVRIQLFFVDKRRNKAVDLIHHLKLDNSHSGRQLLGGERSIEIELDRNTDFKDTNTIPSAVADTPQEPTSNQEEQPPPPSQEEQVQSMAAKQKMSLLNGMLKESVQKLPIIRAGSHGTVLPYTCASSPIMFFKWSVGKRKALEWQRARLLRLQVQSKAFEVNDNVLRTAAELLSTKDVLLWCREHKYTPSRLEDVEEKKSALIMGYCKFCGNVRDEHDETADDHCPQRPKGWNNRKRGGISSLTSVTRLLNRLEVGWDEVKEIDEEMDVDVDVDEQRKSPIGSSTQEKDISTRVQDWALNSDTMDVANERSLDWIWSVVGQLRLKSVIANDMLLAKDGNLQGPTSSFDLAEAMKQRLVVGNILTQATRLFLKRLLNHTVNICRKEEEGSANKSVKMMMPYHVYQAAQQAEEFDFLTNQYMGTEENQTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MX11</accession>
    <name>A0A1C7MX11_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transposon TX1 uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">YTX2_10</name>
        <name evidence="3" type="ORF">A0J61_10594</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001255">
        <property type="protein sequence ID" value="OBZ81357.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MX11"/>
    <dbReference type="InParanoid" id="A0A1C7MX11"/>
    <dbReference type="OrthoDB" id="2212429at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01650">
        <property type="entry name" value="RT_nLTR_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043502">
        <property type="entry name" value="DNA/RNA_pol_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000477">
        <property type="entry name" value="RT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026960">
        <property type="entry name" value="RVT-Znf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19446">
        <property type="entry name" value="REVERSE TRANSCRIPTASES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00078">
        <property type="entry name" value="RVT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13966">
        <property type="entry name" value="zf-RVT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56672">
        <property type="entry name" value="DNA/RNA polymerases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Reverse transcriptase" evidence="1">
        <location>
            <begin position="139"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="domain" description="Reverse transcriptase zinc-binding" evidence="2">
        <location>
            <begin position="562"/>
            <end position="633"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="729"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ81357.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="729" mass="81922" checksum="03CAF0C6597FF7A2" modified="2016-11-30" version="1" fragment="single">NGETSTGYLKSTISSRTVNRNIPTLQHPYTNQVCTSNSDIESAATTFDETLNTPSPVDDTSISTLAATIPSRLQLNFAQQKTLLLPLTLTELQDGTERSPNHSSPGTDGLPYEILSILLHHPDTDLRNWRPISLINDLRNWRPISLINTDANIFTRPLNQRLMTHMSSSISSHQLGFMPNRFIADHGLSLHIAQLIATHTRCSTIALLLDQEKAYDRVHSGYLSTIMSRFGISTQLIGCIHSLFFPTHIAININGHLTTTPGDPLNPLLFNIAFDPFLRLIHQNTLFAGFNFSKEAPPHQQLDDDFDDIVSSISNLFISSTSLPEPSPDPIPVTPPSPHSSLTVKILAYADDTPVFLRNHHELNHLLSAIRIYSTASNAHLNFHKTEVISLSGQSLPQWRHLLSLHNIHSWHDKYSPSPAIYLGFLIISSLKQRSVAYDKLETTISSACDIHSQRNLSVRGRATMLRLEPKRPPFTHSRHRNLTTKTHRLLQSGLLKFHPFLEHNCCLAPRITPASTTTLDLAPFVKSLLTLPPTHRGPLASIRAYKTLTTPSLRNVTSTLSSSNWSIFWSLPIPLQARTVCYRLLHNKIPNRSFLHNLNPSSFPGPLCHICSTTTESVDHFFCLCPSKAQLWLRILSSYINSLLEVVFSDIPHLLHCVYRFVPVTPFRDPSLPLPTLSIDQIFACTSLGIWQTQWQSIFQTAPFSTAAAINRSLHHLYFLEQQRFTQH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MXA7</accession>
    <name>A0A1C7MXA7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Minor extracellular protease vpr</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">vpr_1</name>
        <name evidence="7" type="ORF">A0J61_10508</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the peptidase S8 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001208">
        <property type="protein sequence ID" value="OBZ81443.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MXA7"/>
    <dbReference type="STRING" id="101091.A0A1C7MXA7"/>
    <dbReference type="InParanoid" id="A0A1C7MXA7"/>
    <dbReference type="OrthoDB" id="206201at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.200">
        <property type="entry name" value="Peptidase S8/S53 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000209">
        <property type="entry name" value="Peptidase_S8/S53_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036852">
        <property type="entry name" value="Peptidase_S8/S53_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050131">
        <property type="entry name" value="Peptidase_S8_subtilisin-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43806">
        <property type="entry name" value="PEPTIDASE S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43806:SF66">
        <property type="entry name" value="SERIN ENDOPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00082">
        <property type="entry name" value="Peptidase_S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52743">
        <property type="entry name" value="Subtilisin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51892">
        <property type="entry name" value="SUBTILASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 7" id="KW-0645">Protease</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0720">Serine protease</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008889353" evidence="5">
        <location>
            <begin position="27"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S8/S53" evidence="6">
        <location>
            <begin position="175"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="340"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OBZ81443.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="340" mass="36632" checksum="EB8488833C3D6942" modified="2016-11-30" version="1" fragment="single">MKPSLFAFPGLAMWACLALTSLVTEAAELKHAKLMSADYDAIAGRYIVQFKKNNSLAGKTFAHSVQQALSNNGVEIKETINHRIFSGASIDITDVGESALKPILDREDVEAIYPVRRIYHASTSGVAPSVKNESYIGKRLFAEKRKTPEKQVDDFNIPLVLGQVDQVHSKLGYKGKGILVGIIDSVYANCPQLGLDYMHPALGGGFGKGYKVVAGYDLVGDAFDFDMEPQPDADPYDSCSTSADSISDQLLCTPVLILISKAHATHIAGIIAGYSEKQGFTGVAPEASLGIWRVFGCQGSTSSDMMIKAMLMAYDAGVDIISMSISYNYLRYGYGGVEAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MXF7</accession>
    <name>A0A1C7MXF7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Versiconal hemiacetal acetate reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">vrdA_3</name>
        <name evidence="3" type="ORF">A0J61_10451</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001180">
        <property type="protein sequence ID" value="OBZ81500.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MXF7"/>
    <dbReference type="FunCoup" id="A0A1C7MXF7">
        <property type="interactions" value="24"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7MXF7"/>
    <dbReference type="InParanoid" id="A0A1C7MXF7"/>
    <dbReference type="OrthoDB" id="37537at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd19079">
        <property type="entry name" value="AKR_EcYajO-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.100:FF:000004">
        <property type="entry name" value="Oxidoreductase, aldo/keto reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="entry name" value="NADP-dependent oxidoreductase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050523">
        <property type="entry name" value="AKR_Detox_Biosynth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036812">
        <property type="entry name" value="NAD(P)_OxRdtase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023210">
        <property type="entry name" value="NADP_OxRdtase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43364:SF4">
        <property type="entry name" value="NAD(P)-LINKED OXIDOREDUCTASE SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43364">
        <property type="entry name" value="NADH-SPECIFIC METHYLGLYOXAL REDUCTASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00248">
        <property type="entry name" value="Aldo_ket_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51430">
        <property type="entry name" value="NAD(P)-linked oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NADP-dependent oxidoreductase" evidence="2">
        <location>
            <begin position="21"/>
            <end position="336"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ81500.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="344" mass="39443" checksum="49D0B051DE7C8831" modified="2016-11-30" version="1">MTPKTKMQYVRFGNTGMRVSRLTLGCMSYGSPDWQQWVKGEEESLKLIKKAYDAGINFFDTANVYSSGESERILGKAIKKFQMPRSRIVVATKVFFPLDPVSYTASNQNNLELENVNDCGLSRKHIFDAVEASLERLGLEYIDLYQIHRADRNTPMEETMEALNDLVRSGKVRYIGCSSCYAWEFQKMNNIAEKRGWAKFVSMQNCYNLLYREEEREMLPYCKDAGIAVIPWSPLARGILTGKNRNTSRTESDSRISRYFGKEEKDVNNQTVDRVIELAEKHGCTPSQVAIAWMLTKSEITSPIVGIGKEEHLYDLIGSFEVTLSESEIKYLEELYTPRNLFPM</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MXX2</accession>
    <name>A0A1C7MXX2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_10293</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001106">
        <property type="protein sequence ID" value="OBZ81658.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MXX2"/>
    <dbReference type="InParanoid" id="A0A1C7MXX2"/>
    <dbReference type="OrthoDB" id="2290007at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ81658.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="281" mass="31895" checksum="D803665503D67F0F" modified="2016-11-30" version="1">MTESSWREAKKQLAEIEVQLTEESMFAEDWFSYCHTMFKKPSLYGFLSSCNETAFNHHVIWPLMDISIDTAKPDLKLMFAEYLLKCSADEYKADGCIIDEFENEICLLETSSSFQYKESGKLGYDHVKGAFGTLTLFNAIFKKYHHAPIDTAINLTITFVHARGDSLHLWNLELCSKKVYALKKVYKTKVPTSQADTTNVLALGNFSWCLKECLEKSCKTIEKMKEEHESFEVRVLMGEPAQSSLLEMVDTDIKKPVKGAGYGILLPEEKGDDEVAVSFIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MY27</accession>
    <name>A0A1C7MY27_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 14">Aurora kinase</fullName>
            <ecNumber evidence="1 14">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="primary">Aurkb</name>
        <name evidence="16" type="ORF">A0J61_10242</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="14">Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. Aurora subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="1 14"/>
    <dbReference type="EMBL" id="LUGH01001083">
        <property type="protein sequence ID" value="OBZ81712.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MY27"/>
    <dbReference type="STRING" id="101091.A0A1C7MY27"/>
    <dbReference type="InParanoid" id="A0A1C7MY27"/>
    <dbReference type="OrthoDB" id="377346at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032133">
        <property type="term" value="C:chromosome passenger complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000776">
        <property type="term" value="C:kinetochore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051233">
        <property type="term" value="C:spindle midzone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008608">
        <property type="term" value="P:attachment of spindle microtubules to kinetochore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045143">
        <property type="term" value="P:homologous chromosome segregation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044779">
        <property type="term" value="P:meiotic spindle checkpoint signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032465">
        <property type="term" value="P:regulation of cytokinesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090266">
        <property type="term" value="P:regulation of mitotic cell cycle spindle assembly checkpoint"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902115">
        <property type="term" value="P:regulation of organelle assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072479">
        <property type="term" value="P:response to mitotic cell cycle spindle assembly checkpoint signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd14007">
        <property type="entry name" value="STKc_Aurora"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000042">
        <property type="entry name" value="Aurora kinase A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000235">
        <property type="entry name" value="Serine/threonine-protein kinase ark1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030616">
        <property type="entry name" value="Aur-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24350">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE IAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 11 13" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 14 16" id="KW-0418">Kinase</keyword>
    <keyword evidence="5 11 13" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 14" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="4 14" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="15">
        <location>
            <begin position="96"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="10">
        <location>
            <position position="219"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="106"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11 13">
        <location>
            <position position="125"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="174"/>
            <end position="176"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="223"/>
            <end position="224"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="235"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="cross-link" description="Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)" evidence="12">
        <location>
            <position position="221"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00021157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR630616-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR630616-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR630616-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU367134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="OBZ81712.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="358" mass="41226" checksum="302BD5FDACE0E042" modified="2016-11-30" version="1">MQNKEEDFNYVDYTPRRAINSTSRIPTTPNKLTLAKYRRSYFYQQLAKQDHHELDFMDSPAVRRHFGISETVAVLDDKPPSVHLPQRTTPWTIQDFVVGEHLGKGKFGSVYKAQEVNSGQIVALKILKKKELEQHKVEPFIKREIEIQGHLNHPTITRLYGYFHDQEQIYLVLEYAGDKDLYSCLETHGVFTETEAANSIVEIANGLAYMHQLGVFHRDIKLENSNDDGTLKIADFGWAVYDPNPRRNTFCGTLDYLPPEMIQRQSHGATVDIWALGILCYELLVGQAPFEDPKDRLEQEGHEATYRRIVEARITFPPDLSDGARQFILKCLQKNPSQRISMASVAYDPWIQSNKRID</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MY57</accession>
    <name>A0A1C7MY57_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Sugar phosphatase YfbT</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">yfbT_1</name>
        <name evidence="1" type="ORF">A0J61_10243</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001083">
        <property type="protein sequence ID" value="OBZ81711.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MY57"/>
    <dbReference type="STRING" id="101091.A0A1C7MY57"/>
    <dbReference type="InParanoid" id="A0A1C7MY57"/>
    <dbReference type="OrthoDB" id="40579at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050308">
        <property type="term" value="F:sugar-phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07527">
        <property type="entry name" value="HAD_ScGPP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.240">
        <property type="entry name" value="Putative phosphatase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051806">
        <property type="entry name" value="HAD-like_SPP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006439">
        <property type="entry name" value="HAD-SF_hydro_IA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023198">
        <property type="entry name" value="PGP-like_dom2"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01509">
        <property type="entry name" value="HAD-SF-IA-v3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43481">
        <property type="entry name" value="FRUCTOSE-1-PHOSPHATE PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43481:SF4">
        <property type="entry name" value="GLYCEROL-1-PHOSPHATE PHOSPHOHYDROLASE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00702">
        <property type="entry name" value="Hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01135">
        <property type="entry name" value="C1.5.6:_HAD__Beta-PGM__Phospha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01129">
        <property type="entry name" value="C1.5:_HAD__Beta-PGM__Phosphata"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00003">
        <property type="entry name" value="Haloacid_Dehalogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ81711.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="220" mass="24212" checksum="0D24A37222A18A6A" modified="2016-11-30" version="1">MTVETIQTNAVVFDLDGTLVDTTPQVIKFWTELAKENNIDPAQVLATSHGRRTIETLERWMPHLATVEHVMALEEKLASDKEGVVLLPGVMDLLNKIDPDDWTICTAGTFPMAIGRLNQFGIKAPPKMVTGDKLSFGKPHPEGYLLAAHYLNRDPKACVVFEDAPAGVQAAIAAGMTCIACTTTHTYEQLKEAGATFIVERLDRVHIEKSKEGHYTITIQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MYC0</accession>
    <name>A0A1C7MYC0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Reverse transcriptase zinc-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_10151</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001052">
        <property type="protein sequence ID" value="OBZ81802.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="InParanoid" id="A0A1C7MYC0"/>
    <dbReference type="OrthoDB" id="2273311at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ81802.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="334" mass="37982" checksum="13661C5A58652D2E" modified="2016-11-30" version="1">MRPAPLRHXTSPLSLLFKSVDALPKLXAQVVISPXTCLPIPLGSLHIQPATFEVPRSIQHLACSTAYVLDRXSGRLRPKTPSEXTSSPYLVRKFLRWVRRXEVVLLPFFVRAFIPXAXAMIGSHPFVQVEHDLVDATPLLLSLGLSSVDPDLYLSSKSYXSQLLPPSNSRLPARLWSEXWSFSLTPTSRNVWYRLLLGKLPCRSTLHCVLPFIEEPLCNICSQKIDTXEHFLYECDRKLIVWEXIWSQHFSTXFTTXHLHAALFNLQFPPLAQFSSQNEAYIILASILXXVWRSHWLYVFDKVPFVSTAIIASANKDLHHHTNEALFRKGTLLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MYF9</accession>
    <name>A0A1C7MYF9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Ubiquitin carboxyl-terminal hydrolase</fullName>
            <ecNumber evidence="5">3.4.19.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">usp22</name>
        <name evidence="9" type="ORF">A0J61_10081</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11 12">
            <text>Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).</text>
            <dbReference type="EC" id="3.4.19.12"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the peptidase C19 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.19.12" evidence="5"/>
    <dbReference type="EMBL" id="LUGH01001024">
        <property type="protein sequence ID" value="OBZ81870.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MYF9"/>
    <dbReference type="FunCoup" id="A0A1C7MYF9">
        <property type="interactions" value="248"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7MYF9"/>
    <dbReference type="InParanoid" id="A0A1C7MYF9"/>
    <dbReference type="OrthoDB" id="289038at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004843">
        <property type="term" value="F:cysteine-type deubiquitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016579">
        <property type="term" value="P:protein deubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.70.10">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050164">
        <property type="entry name" value="Peptidase_C19"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001394">
        <property type="entry name" value="Peptidase_C19_UCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028889">
        <property type="entry name" value="USP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018200">
        <property type="entry name" value="USP_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001607">
        <property type="entry name" value="Znf_UBP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24006">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24006:SF937">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00443">
        <property type="entry name" value="UCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02148">
        <property type="entry name" value="zf-UBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00290">
        <property type="entry name" value="ZnF_UBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00972">
        <property type="entry name" value="USP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00973">
        <property type="entry name" value="USP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50235">
        <property type="entry name" value="USP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50271">
        <property type="entry name" value="ZF_UBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0645">Protease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0788">Thiol protease</keyword>
    <keyword evidence="5" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="UBP-type" evidence="8">
        <location>
            <begin position="90"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="domain" description="USP" evidence="7">
        <location>
            <begin position="221"/>
            <end position="549"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="377"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="392"/>
            <end position="407"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU366025"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50271"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OBZ81870.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="549" mass="62979" checksum="FB80D12C7C8AEC44" modified="2016-11-30" version="1">MSHPQAPNSPLSPLSPLSPSQTPTSPATQPKTIYDILYSKNNPPEFYGPQQLIQSSACSHLAQLKQSLREGSHQENILENYRALVQYSLVWHKSRKSIVKRKELKELPLPQCTTCLDPLSRLHACLHCVYLGCWKKGHMKDHQKEKKHIFAMEFDRHAIFCSECDDYVYDVEIDEKITRHELMSNARRKKQKVHYVSWEPTKQEIPTLVHHATINSCQGIRGLCNMGNTCFMNVILQSFVHNPLLKAYFLSDRHNPKHCQKQYCMCCEMDDLFTQFYSDDKKPYGPCRFLQSMWMSLKELAGYAQQDAHEFFISALNNIHAGCKEQKLANCECIIHKTFAGLLQSNVTCLRCRNVTTTCDPMLDISLGLRPVEKKKSTKAGHDSRLLSGHQATDKNGRRSSHDDPARANKQGNTLLDCLDRYTQPEKLGPNEYSCSKCGNTFQEATKQLSIKRIPPVLSIQLKRFEHGTSTSKIETKIKFPVELDLTPYTSNKSKDSDNVYTLFSVVNHQGKVDTGHYTMFAKHRNEWFRFDDHNVTLAYQKDVLDSRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MYQ8</accession>
    <name>A0A1C7MYQ8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Arf-GAP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">A0J61_10044</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001011">
        <property type="protein sequence ID" value="OBZ81908.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MYQ8"/>
    <dbReference type="FunCoup" id="A0A1C7MYQ8">
        <property type="interactions" value="445"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7MYQ8"/>
    <dbReference type="InParanoid" id="A0A1C7MYQ8"/>
    <dbReference type="OrthoDB" id="10266696at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd08839">
        <property type="entry name" value="ArfGap_SMAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.220.150:FF:000009">
        <property type="entry name" value="stromal membrane-associated protein 1 isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.220.150">
        <property type="entry name" value="Arf GTPase activating protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051718">
        <property type="entry name" value="ARF_GTPase-activating"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037278">
        <property type="entry name" value="ARFGAP/RecO"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001164">
        <property type="entry name" value="ArfGAP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038508">
        <property type="entry name" value="ArfGAP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044732">
        <property type="entry name" value="ArfGAP_SMAP1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45705">
        <property type="entry name" value="FI20236P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45705:SF1">
        <property type="entry name" value="FI20236P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01412">
        <property type="entry name" value="ArfGap"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00405">
        <property type="entry name" value="REVINTRACTNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00105">
        <property type="entry name" value="ArfGap"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57863">
        <property type="entry name" value="ArfGap/RecO-like zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50115">
        <property type="entry name" value="ARFGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0343">GTPase activation</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Arf-GAP" evidence="7">
        <location>
            <begin position="18"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="152"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="176"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="192"/>
            <end position="220"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022468"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50115"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OBZ81908.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="270" mass="30776" checksum="3AC5591C5C9D4D7E" modified="2016-11-30" version="1">MTTRHARVADKELNEKHTKILAALLDEEDNSYCADCRKKDPRWASWNLGIFVCIRCSGIHRSLGTHISKVKSVDLDTWTPEQIENMTKWGNRRARMYWEAEIGNGKPSEANMDVWIRAKYEHKRWVSRQEQHELLKHSQLICKKEKERLAKEQLTKERNTDGQNVKKKSFESGIDDIPKPTKDTGKSAHEGSSLQPSKTSLSSLQSQFSQLALNNSQSSNMIPKAPPGSDMSWTNFLVSDKPKDNTNILSEPSKEKPLISFDALASLLKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MYY0</accession>
    <name>A0A1C7MYY0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Tc1-like transposase DDE domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_11617</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01002264">
        <property type="protein sequence ID" value="OBZ80334.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MYY0"/>
    <dbReference type="InParanoid" id="A0A1C7MYY0"/>
    <dbReference type="OrthoDB" id="5410741at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ80334.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="77" mass="8565" checksum="E393AD7673EABD1C" modified="2016-11-30" version="1" fragment="single">MWQGLSNGLRRYLGMKQVLFGDHAQELTCKSIPNAILAEGNASMHRSKSAETWKTAHGIAKTEWPDQSLNLSPVENL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MZ17</accession>
    <name>A0A1C7MZ17_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Sorbose reductase SOU1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">SOU1</name>
        <name evidence="4" type="ORF">A0J61_09939</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000976">
        <property type="protein sequence ID" value="OBZ82011.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MZ17"/>
    <dbReference type="FunCoup" id="A0A1C7MZ17">
        <property type="interactions" value="43"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7MZ17"/>
    <dbReference type="InParanoid" id="A0A1C7MZ17"/>
    <dbReference type="OrthoDB" id="1669814at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050085">
        <property type="term" value="F:mannitol 2-dehydrogenase (NADP+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050664">
        <property type="term" value="F:oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044281">
        <property type="term" value="P:small molecule metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000090">
        <property type="entry name" value="NADP-dependent mannitol dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF005559">
        <property type="entry name" value="PRK07231.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43008">
        <property type="entry name" value="BENZIL REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43008:SF4">
        <property type="entry name" value="CHAIN DEHYDROGENASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_4G08710)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13561">
        <property type="entry name" value="adh_short_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OBZ82011.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="263" mass="28175" checksum="FEE03EEB1C8114B9" modified="2016-11-30" version="1">MSAPLPVLPEFSLKDKVAIVTGGGRGLGLEMSKALAESGAKVAIMYVSSDKTKDTAADIAKQFNVKCEAYKAPINDAEAVKQVIDQIHKDFGSIDILVANAGVNTGGASETFDLKEWQKVMDINVNGVFYSIQAAAKHMLQKGKGSIIITSSISGAVANRPQLQCVYNTSKGATTMMAKCLATEWAQKGIRVNALCPGYMRTELLDATFKDDPEWEKIWCDMTPMGRIGDAKELRGAIVFLASDASTYVTGTELFVDGGYTAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MZ62</accession>
    <name>A0A1C7MZ62_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Arabinose 5-phosphate isomerase KdsD</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">kdsD</name>
        <name evidence="4" type="ORF">A0J61_11527</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01002150">
        <property type="protein sequence ID" value="OBZ80424.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MZ62"/>
    <dbReference type="STRING" id="101091.A0A1C7MZ62"/>
    <dbReference type="InParanoid" id="A0A1C7MZ62"/>
    <dbReference type="OrthoDB" id="1872003at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097367">
        <property type="term" value="F:carbohydrate derivative binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016853">
        <property type="term" value="F:isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901135">
        <property type="term" value="P:carbohydrate derivative metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05014">
        <property type="entry name" value="SIS_Kpsf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.580.10">
        <property type="entry name" value="CBS-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10490">
        <property type="entry name" value="Glucose-6-phosphate isomerase like protein, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046342">
        <property type="entry name" value="CBS_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004800">
        <property type="entry name" value="KdsD/KpsF-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001347">
        <property type="entry name" value="SIS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046348">
        <property type="entry name" value="SIS_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035474">
        <property type="entry name" value="SIS_Kpsf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00393">
        <property type="entry name" value="kpsF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38418">
        <property type="entry name" value="SUGAR ISOMERASE, KPSF/GUTQ (AFU_ORTHOLOGUE AFUA_6G08860)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38418:SF2">
        <property type="entry name" value="SUGAR ISOMERASE, KPSF_GUTQ (AFU_ORTHOLOGUE AFUA_6G08860)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01380">
        <property type="entry name" value="SIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53697">
        <property type="entry name" value="SIS domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51464">
        <property type="entry name" value="SIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0129">CBS domain</keyword>
    <keyword evidence="4" id="KW-0413">Isomerase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="SIS" evidence="3">
        <location>
            <begin position="47"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="268"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OBZ80424.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="268" mass="28484" checksum="BF01CBE1C3655175" modified="2016-11-30" version="1" fragment="single">MFNTTEEIIDNATNILIQEATCIHNAAQRLKNNMDTKDGFEQAIYLMFKSLDAGGKIVVTGVGKSGKIGEKIVATMLSTGICSTFLHPVEALHGDLGTVQPNDAVLALSFSGNTEELLMLLPSLKHRSVPVIGLGGNSKSKLAKECAAWIDGYVESEAGGDMPAPTSSTTLALALGDALALTLAKLRNFTTDGFALNHPGGSLGRKLLLKVKDIVIDASKVATVSKNTSLDVVIMQMTRYPRGSSVIVLEDESLDSRTLDGDQSYLFP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MZF9</accession>
    <name>A0A1C7MZF9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Phosphatidylinositol N-acetylglucosaminyltransferase subunit H</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">PIGH</name>
        <name evidence="5" type="ORF">A0J61_09787</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Glycolipid biosynthesis; glycosylphosphatidylinositol-anchor biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the PIGH family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000937">
        <property type="protein sequence ID" value="OBZ82162.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MZF9"/>
    <dbReference type="FunCoup" id="A0A1C7MZF9">
        <property type="interactions" value="82"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7MZF9"/>
    <dbReference type="InParanoid" id="A0A1C7MZF9"/>
    <dbReference type="OrthoDB" id="6256716at2759"/>
    <dbReference type="UniPathway" id="UPA00196"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000506">
        <property type="term" value="C:glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006506">
        <property type="term" value="P:GPI anchor biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044215">
        <property type="entry name" value="PIG-H"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019328">
        <property type="entry name" value="PIGH-H_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15231">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL N-ACETYLGLUCOSAMINYLTRANSFERASE SUBUNIT H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15231:SF1">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL N-ACETYLGLUCOSAMINYLTRANSFERASE SUBUNIT H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10181">
        <property type="entry name" value="PIG-H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="41"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="domain" description="Phosphatidylinositol N-acetylglucosaminyltransferase subunit H conserved" evidence="4">
        <location>
            <begin position="78"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009610"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF10181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OBZ82162.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="147" mass="16972" checksum="C1660D2C82B10F4D" modified="2016-11-30" version="1">MTHGQDEIYTIGLLTCHWLPGNQACEYSVDSESPLLSSVDLVILSIAFLLCWYASLILGFIILCIWYLLKRASVRKESILAIRDVGIQIKTVYWNGSTFSRFIDRLKVEDIVINEGISFWQIKSYLAILIKDQEDMVVVFEVRIRQH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MZL6</accession>
    <name>A0A1C7MZL6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_09614</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000891">
        <property type="protein sequence ID" value="OBZ82335.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MZL6"/>
    <dbReference type="STRING" id="101091.A0A1C7MZL6"/>
    <dbReference type="InParanoid" id="A0A1C7MZL6"/>
    <dbReference type="OrthoDB" id="2258064at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="57"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="614"/>
            <end position="638"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="675"/>
            <end position="769"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="792"/>
            <end position="843"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="192"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="426"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="17"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="57"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="82"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="107"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="624"/>
            <end position="633"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="679"/>
            <end position="689"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="690"/>
            <end position="699"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="718"/>
            <end position="734"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="742"/>
            <end position="751"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="819"/>
            <end position="828"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ82335.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="843" mass="94456" checksum="FA9283E1C845C885" modified="2016-11-30" version="1">MAETTGEDGSWLKKRSSVFSATNSSTNNAKPVGKPADKELARLKTMGAVSSVWTNKFVQEDSGNSTTGGTRRSFVLPKSPEKTNSPRARGSTSSISSVIDTQENQVSLRKPSRASSSSLELNSSTEEIKSTRSSIQSTRDDISTARSSISSVKSQPKSEEPTTKANSLLGLHKPTKSSDEHETEAASLWFQAETLKTQLAQSNARLSRANEDIEFYKRQLEASGQSIAEMTEEKDKELRHWVDLVLKQDQLLSQYELHLEDLKEQSDSSAPKEDTTALRKELDLLYKQKDQMEGTITSLRAELEMSSSQMQLMMTVSTEIQNEFQSYKQKVDAQIKEVLKQKQAEHDAELEALKLSLNGEPTQRNVGTAVAAAVVGATVATGAVVAQEDPRAQIEKAVAEATAHHEQELDQFRQQIITLTELLHANERSGAKEAELREQIDVLTEQLHAKENAVDDHDAALETLREQIITLTTMLHDKDKAVQDLENQLKVQKRTMDAQVMELTQTILEKDSLLMEQSNNRSRETIIPNIEPHAASSAPSVSETEMFYQSSQHQDIAEARLQMAQVQQYMYSSSEDGDEEDEVEVLRMSYSSDEEEDRGIHRHSFHSQHLIASNDHHVPHSPADTISSNISYDSSDDEYQQEKIAEIKHFSYSSQATRPVSLVSGEHMMLNDENRRLSQRSSSHSQFSHHSLHSHHSHHSNTPTRFSLVKETSSASWPMPPPTPPPSEPLPPVPIMDEKSSTESTIATNSIIPPPRRTRSKTMSRSDAPNMSLYTTSIHQTNELPRIMPEAQQVSPHKERHSGLFQSPQEEPHTKWMDDPESEEDDLWCEPKPRQEWGTATAM</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MZP9</accession>
    <name>A0A1C7MZP9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Protein BOI2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">A0J61_09631</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000895">
        <property type="protein sequence ID" value="OBZ82317.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MZP9"/>
    <dbReference type="InParanoid" id="A0A1C7MZP9"/>
    <dbReference type="OrthoDB" id="73680at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd09535">
        <property type="entry name" value="SAM_BOI-like_fungal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.40">
        <property type="entry name" value="SH3 Domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.50">
        <property type="entry name" value="Transcription Factor, Ets-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001660">
        <property type="entry name" value="SAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013761">
        <property type="entry name" value="SAM/pointed_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036028">
        <property type="entry name" value="SH3-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001452">
        <property type="entry name" value="SH3_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07647">
        <property type="entry name" value="SAM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00018">
        <property type="entry name" value="SH3_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00454">
        <property type="entry name" value="SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00326">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47769">
        <property type="entry name" value="SAM/Pointed domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50044">
        <property type="entry name" value="SH3-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50105">
        <property type="entry name" value="SAM_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50002">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0728">SH3 domain</keyword>
    <feature type="domain" description="SH3" evidence="4">
        <location>
            <begin position="2"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="domain" description="SAM" evidence="5">
        <location>
            <begin position="131"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="103"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="205"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="262"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="103"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="262"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="296"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="308"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50105"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OBZ82317.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="308" mass="34359" checksum="CBAE875501811773" modified="2016-11-30" version="1" fragment="single">MSEPEVVYTVHKFVAENVDEISIDVGEKVVILEKDEGYNDGWFQGRNERGEIGLFPITYTARQLPPMINSSELGNKIDSLENTISKMKPTPIVTKPIENSSASLSISPLPKNSQLSTMQSTDKASKPVEEWSSDQVAAWLMSIGFDKELADNFKDQEISGDILLELTLDSLKELQITTFGKRFKVHNAINSLRQGNKKNYANDTISQNQIESRNATPMTEVPTSRDTFSSFYHNNSNKQQQQVYPDDDLVSNYSTVIRSSQLRDSGKLNGSQSLSVRAPSIHSTRSPISPDIESAPFSSRMSNITETQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MZS3</accession>
    <name>A0A1C7MZS3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="15">Putative ATP-dependent helicase C23E6.02</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">A0J61_09668</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SNF2/RAD54 helicase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000905">
        <property type="protein sequence ID" value="OBZ82282.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MZS3"/>
    <dbReference type="FunCoup" id="A0A1C7MZS3">
        <property type="interactions" value="402"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7MZS3"/>
    <dbReference type="InParanoid" id="A0A1C7MZS3"/>
    <dbReference type="OrthoDB" id="448448at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008094">
        <property type="term" value="F:ATP-dependent activity, acting on DNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000724">
        <property type="term" value="P:double-strand break repair via homologous recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd18008">
        <property type="entry name" value="DEXDc_SHPRH-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18793">
        <property type="entry name" value="SF2_C_SNF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10810">
        <property type="entry name" value="Tandem AAA-ATPase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038718">
        <property type="entry name" value="SNF2-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049730">
        <property type="entry name" value="SNF2/RAD54-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000330">
        <property type="entry name" value="SNF2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050628">
        <property type="entry name" value="SNF2_RAD54_helicase_TF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018957">
        <property type="entry name" value="Znf_C3HC4_RING-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017907">
        <property type="entry name" value="Znf_RING_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45626:SF16">
        <property type="entry name" value="ATP-DEPENDENT HELICASE ULS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45626">
        <property type="entry name" value="TRANSCRIPTION TERMINATION FACTOR 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00176">
        <property type="entry name" value="SNF2-rel_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00097">
        <property type="entry name" value="zf-C3HC4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00518">
        <property type="entry name" value="ZF_RING_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6 15" id="KW-0347">Helicase</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 9" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="13">
        <location>
            <begin position="325"/>
            <end position="511"/>
        </location>
    </feature>
    <feature type="domain" description="RING-type" evidence="12">
        <location>
            <begin position="674"/>
            <end position="717"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="14">
        <location>
            <begin position="777"/>
            <end position="939"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="246"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="10">
        <location>
            <begin position="736"/>
            <end position="766"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="247"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="266"/>
            <end position="277"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007025"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="OBZ82282.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="963" mass="109410" checksum="62519E2E59A1C76A" modified="2016-11-30" version="1">MHSPGIQVFEISDTDSVYETPSESHPTESDCVFDLTSDKQKDMLDDDTYAFFVEAGLEDPDELAMLGINLDEIKQQRQIEERLETQNKRDFELAAQLQQQLQAEGRTNMAQAMTQTTLPTAFHWTPPIKREEMEQEEAAKRLRTEKGKQAIEINDEVCIDLTNDDDIYQIQTISDDEEDITPPMTDYEQLRFLMGNNTLNPFAPSSSSTTFPPPPASSYAVPYYPYFVHNVNGKRRMVFPTPIVSRAPQSKGTQRPLQPHPGAPYTPTTYTRPLSQQETERELASLLENVVDDDPPPPEDRAGTPDGLNINLLEHQKVGLQWMMKMENSNNKGGLLADDMGLGKTIQAMAVIVQNPCRDVTEFDPDYLINPPQTIVDDVIRVKTTLIVCPVSLMDQWRREIQEKTTPPLRVMVYHGAGRTNNPYEFSQYDVVISSYSVTANNFHDTQKGPMSKVRFHRVILDEAHTIKNKQTFGARGCCQIEATYRWCLTATPIQNKIEELYSLIKFLRIRPFCDWEEFRESIVKPMKAGNHRKAIRVAHLLMKAISMRRSKKAKIDGRPILDLPERNVHMTHIDFSPDERTHYDFVEQRAQARFNKYLQAGSVMKNYSSVLVLLLRLRQACLHPNLTFVEGDGEVPAGESANPEKQEQLARQMKPDVVRRLLSDATSIAEIECPICLDIAQDAQIAKECGHILCKECLDNFINTNDGATKRCPHCRGDISKANMVPLEAFLKVHAPDLIKEAEAAEQQEKDEEAASKDKEEKEALARVHEFISSAKIDKMIEILKETNATTNNQDKTIVFSQFTAFLDLIETPLKHEGFKYLRYDGSMDIKSRADTVSKFFEDPEYTVLLVSTKCGSLGLNLTCANRVILMDIWWNPALENQAIDRVHRIGQRKPVDVHRIFINRTVEDRILELQKKKQSIADGVLGEGSHKSTSRLGLQEMIYLFRGGDVPEPNAPNPPVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N008</accession>
    <name>A0A1C7N008_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Actin-like protein 6A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">ACTL6A_0</name>
        <name evidence="3" type="ORF">A0J61_09510</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the actin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000866">
        <property type="protein sequence ID" value="OBZ82440.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N008"/>
    <dbReference type="FunCoup" id="A0A1C7N008">
        <property type="interactions" value="203"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N008"/>
    <dbReference type="InParanoid" id="A0A1C7N008"/>
    <dbReference type="OrthoDB" id="5132116at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd13395">
        <property type="entry name" value="ASKHA_NBD_Arp4_ACTL6-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.40:FF:000050">
        <property type="entry name" value="Actin, alpha skeletal muscle"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.40:FF:000058">
        <property type="entry name" value="Putative actin-related protein 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.640.10">
        <property type="entry name" value="Actin, Chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004000">
        <property type="entry name" value="Actin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004001">
        <property type="entry name" value="Actin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11937">
        <property type="entry name" value="ACTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00022">
        <property type="entry name" value="Actin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00190">
        <property type="entry name" value="ACTIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00268">
        <property type="entry name" value="ACTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00432">
        <property type="entry name" value="ACTINS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="313"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="317"/>
            <end position="326"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU000487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ82440.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="449" mass="50893" checksum="2FD559C539E439FE" modified="2016-11-30" version="1">MVAYGGDEVNALVLDIGTSTTRAGYAGEDTPRVMFPTSVGYIDTPSIESDGDTLMTDSTENKKKRNYFIGDNKINKFRSQMEITHPLQDGLVNDWDAYEAIWHATFDDMLRIRPEEHPLLCTEPAWNTKENREKTIELAFEKFEFPAFYLVPDAVMTAFSVGRATALVLDSGAGVTSAVPVYDGFVLNRGVLHQPLAGNRLAEKIQEQLKAELNYTITPRFKIAKKKPVELDQQPELELNACEGLRESFEQDQILKIINEYKETVCQLSDVTYDEGLLSSRPKMLFEFPDGYQHQFGIERYRVSELLFQPNMNQQQKGEEEPRQQQEEEEQDTNQEKESEEKQLLGVHDLVYNSISACDIDLRPLLFNNVVVTGGNTLIQGFNERLNYELPLKAPASKIKIHAAGNATERKSSSWLGGSIVASLGTFHQLWISRQEYEEHGVSVIHRKC</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N0E2</accession>
    <name>A0A1C7N0E2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_09457</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000855">
        <property type="protein sequence ID" value="OBZ82491.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N0E2"/>
    <dbReference type="STRING" id="101091.A0A1C7N0E2"/>
    <dbReference type="InParanoid" id="A0A1C7N0E2"/>
    <dbReference type="OrthoDB" id="2244377at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00229">
        <property type="entry name" value="SGNH_hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1110">
        <property type="entry name" value="SGNH hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036514">
        <property type="entry name" value="SGNH_hydro_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52266">
        <property type="entry name" value="SGNH hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ82491.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="497" mass="57413" checksum="E4741ECFD3D8C7CB" modified="2016-11-30" version="1">MQSTLVQHRHLILTTLFLTCILTSFYLFYTPSQAAVHHTAQKKPKQPITLCDQVDAAWLASDRIYWDGWKDKAMFMKRDGTLTKGNVYIEQDQDVCIVVLLGPTPAKASIRDEQNDHIGPRDSIVMFANGQYTKKTIQLNQHTEQSNVYMAAVHFSQPDTYELNASTEYRHFFWETPILHAYHPFQFQSQNKLIVQPSKREAKKTCNATSLEGTWVDQAKLAEYDPYMLHQMYENAEIQHSVVNKVFVPDTCQLNYVSIGKVAECLGRQTVHVWADQHVKRNLKALDQPEWCNLEAIAELDDPEARKAAFRCNCNEIGEDPTWWKDSDQPLILDNSLNVHARFYVHSLQGALVSERDRFIQQMELANHTDQADWVIVGIGNDDIEALQVTPKQFEAHLIRFFEQLRKIYPHQRVIVRTPQYFCCSTREGSSWNTGRSLAMTVAMRQVVQNQPNMVLWDVHQLGTDETSCFLTQGSTYSKRHVVNTENQFLWRLLCLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N0N6</accession>
    <name>A0A1C7N0N6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Kelch domain-containing protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">Klhdc1</name>
        <name evidence="6" type="ORF">A0J61_09280</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000815">
        <property type="protein sequence ID" value="OBZ82670.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N0N6"/>
    <dbReference type="STRING" id="101091.A0A1C7N0N6"/>
    <dbReference type="InParanoid" id="A0A1C7N0N6"/>
    <dbReference type="OrthoDB" id="2275515at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.80">
        <property type="entry name" value="Kelch-type beta propeller"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015915">
        <property type="entry name" value="Kelch-typ_b-propeller"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46093">
        <property type="entry name" value="ACYL-COA-BINDING DOMAIN-CONTAINING PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46093:SF18">
        <property type="entry name" value="FIBRONECTIN TYPE-III DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24681">
        <property type="entry name" value="Kelch_KLHDC2_KLHL20_DRC7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117281">
        <property type="entry name" value="Kelch motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0880">Kelch repeat</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008889400" evidence="5">
        <location>
            <begin position="20"/>
            <end position="565"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="431"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="400"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="499"/>
            <end position="520"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="543"/>
            <end position="565"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="499"/>
            <end position="515"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OBZ82670.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="565" mass="61376" checksum="24EC2CCD28DFEF1B" modified="2016-11-30" version="1">MVLLKLAVALLATASTVRGQSIARSGTECAYLTGKVYCFFGSVVKSATESTLENVINVLDLTNATGKSATELDLQWRPVSSNTNGVDITARQLPQSAAVGDGRRIVFTGGYVPSAERLQDDTIIYDAVENKWSKGASYTEPPYGTRQIYYGSGVYVPDRGLAVYGGFEEFINPNWTTPSSNVTAFNFANNKSRTIGYTQVAFFNVDSINQPWSIPVPLSTWTTPFIAFHKSVYDPLKHRILFMGGETRLNDQNNYNTNAEPFPFTKAWTFDTVNNSWLTIDLRGDAPAGARYYHSLTLAPSTGRDVILFGGESDSKALNDYCFTLNLDTNTWKKINIDAPAGTVLARSRHSAVLTTNDTLLILWGLDANRAGISSLLMLNVSDPYAITISNKYFDPNPSISSGNESTVGNTGNSENATSGDSQLSGSAKGGIAAGCIAAAGLIVAAIFFRRKRAQKNKNNLEHSTNFDHTGSHINQEAVPIEVDWDKLEEKYTEVPMQSTQHYQAHSETQGSDMGSTIIRGYSPRLNNETTGASLMNPNSVEDEAAYGGGHSQPMVLKPDVGHNV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N120</accession>
    <name>A0A1C7N120_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">RRM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">A0J61_09633</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000895">
        <property type="protein sequence ID" value="OBZ82319.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N120"/>
    <dbReference type="STRING" id="101091.A0A1C7N120"/>
    <dbReference type="InParanoid" id="A0A1C7N120"/>
    <dbReference type="OrthoDB" id="431169at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd12245">
        <property type="entry name" value="RRM_scw1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.330:FF:000089">
        <property type="entry name" value="RNA binding protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10501">
        <property type="entry name" value="U1 SMALL NUCLEAR RIBONUCLEOPROTEIN A/U2 SMALL NUCLEAR RIBONUCLEOPROTEIN B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="5">
        <location>
            <begin position="48"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="5">
        <location>
            <begin position="438"/>
            <end position="515"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="155"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="329"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="388"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="157"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="203"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="334"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="390"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="4">
        <location>
            <begin position="401"/>
            <end position="410"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OBZ82319.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="553" mass="60908" checksum="27020037B9CF47D7" modified="2016-11-30" version="1">MSQTPTTPLSPTPLNTSFFNVFMNNNTSVSTSLLQQDGPVSTIKEEISTIFVVGFPEDMQEREFQNMFMFSPGFEAATLKVPSKDGEEDFMLNSGSSNGSNGRKQIIGFAKFRTRKEAMDARDILNGRKVDNEKNSMLKAEMAKKNLHTKRGFLTEQPQPSQSTPLQPTQQQQQQQQQQQQQQLQQQLQQLQIQPQPSPSTSRFPNTTTGGNSASAYEAFYSVPHSVPNELMSPNESYSDFYSDLVSPPPDSAFHIARSQSVDARSMDLFVRPSVSTSRFTHQVQSRFAPSSSTSSSLHDGLDYLSKSTPTTDRNATFQAMNAFFANHPHHHSNSLTSSTTTTASNTANSSSSTSTGLNRVMEENNYFFNSAPTAAHHHHHEPLITRFHPLNSSSSTPPKSSSPPPPPGIISPTNSYRSLGGMLVGSSNPADQNPPCNTLYVGNLPSNTNEEELKAMFSKCPGYKRLSFRNKSNGPMCFVEFDDAIYAAQALQELHGNPLSNSIKGGIRLSFSKNPLGVRQNPANSNNNNFSMINAFNRRESITTSSFDPQLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-06-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N1L8</accession>
    <name>A0A1C7N1L8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_09367</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000833">
        <property type="protein sequence ID" value="OBZ82586.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N1L8"/>
    <dbReference type="InParanoid" id="A0A1C7N1L8"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ82586.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="22" mass="2521" checksum="6259A60DB802D7E7" modified="2016-11-30" version="1" fragment="single">MEGILTYVSDPNIVLENITNRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N1T0</accession>
    <name>A0A1C7N1T0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Putative zinc-finger domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_09002</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000753">
        <property type="protein sequence ID" value="OBZ82951.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N1T0"/>
    <dbReference type="STRING" id="101091.A0A1C7N1T0"/>
    <dbReference type="InParanoid" id="A0A1C7N1T0"/>
    <dbReference type="OrthoDB" id="2290160at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019607">
        <property type="entry name" value="Putative_zinc-finger_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10650">
        <property type="entry name" value="zf-C3H1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Putative zinc-finger" evidence="2">
        <location>
            <begin position="805"/>
            <end position="826"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="176"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="521"/>
            <end position="540"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="592"/>
            <end position="714"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="15"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="207"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="521"/>
            <end position="534"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="605"/>
            <end position="621"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="622"/>
            <end position="655"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="664"/>
            <end position="689"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF10650"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ82951.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="832" mass="93438" checksum="C743B975CF5159D6" modified="2016-11-30" version="1">MSRYASGAIRYDSDNGSDMDVSSDDDDMVLTHAQVKPPHENLVQSLRHKIQQKDQPLIQPRVEIFLPYSNHGQPANSYANTLKRVIKIDDDSDTESVDSFKTAPDSLYEEDPLETPASNEVNLDHLQRMIVDLEEQLTATRARGDHIQRLIDEKNAKREALRIKKLEESVRRSIMKRKREAPVTEAPTESEASTEDKALSKKKKRVVDKGKQKAEPPVEQKTEQPQPQQIAVQPMPLLPVQQRTKVSMSSMAARQRYINTMMHNSNINQGIQLPEPTPPLSRKQKKKAHTTVVSTEGPKQTEIKKQVLASFLEGGMTVRQMKILLVDLWHRSIEARLNVFQEVHARELRKRVVPKLQDNDNDTVMFTLKKRGRASYTPPNKLFLPSKFYGHPERLDYNTFELQEDDTWAALEFFTYLSPALVLPKRKTPSAFVVDDENLSLETESMDEHRPTPFLLDMQSDQGRAAHHDIITSLERIRANSEIELPRQTNNRRPLRESHPRKAKDIANELTRLEQTSYQAKQAAKNHKANNNNNTISPFKSQLPLGPTISPLAIMSPPPFNTLAGAMPLPFNAMPQSMNFMPQPMNFMAPPVNFMGNAPHSPVRNTPTRNTPQTTRPAPAQHNNTAPSNNVPRQPTSAPTQHNNAPTQHNNAAPSNNPPRQPANAPTQHINAARQSTSAPAQHNNAPRQPTNPPKQPTHAPKQPTHAPKQPNRASERPIQIITHSTSPAPQPVETKNAASFSASHSFRPYRSVVSSLGVKSTVKELEQQPKSKVLEEAIKPVSHTTSDHPETANTSHVAEKRSELCSAESSGGVCRVKNCPFLHFKDYNTMQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N215</accession>
    <name>A0A1C7N215_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Transmembrane protein 198</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">A0J61_08911</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TMEM198 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000734">
        <property type="protein sequence ID" value="OBZ83041.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N215"/>
    <dbReference type="STRING" id="101091.A0A1C7N215"/>
    <dbReference type="InParanoid" id="A0A1C7N215"/>
    <dbReference type="OrthoDB" id="102260at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025256">
        <property type="entry name" value="TM7S3/TM198-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040236">
        <property type="entry name" value="TMEM198"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31247:SF5">
        <property type="entry name" value="DUF4203 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31247">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 198 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13886">
        <property type="entry name" value="TM7S3_TM198"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="27"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="55"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="85"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="109"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="139"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="164"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="213"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="domain" description="TM7S3/TM198-like" evidence="8">
        <location>
            <begin position="36"/>
            <end position="230"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00049737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF13886"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OBZ83041.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="256" mass="27525" checksum="15C360E52F9361FA" modified="2016-11-30" version="1">MGDFVIAAPVTSVDSNSATITFAGHTATVHGIVFSVILFITGGYLCFLGGVFQSFTMFIVGFYIGGNIAYIVLTNAKPDYGSNTNTILLVVSIVAGILVGGLLCCCFFLAVYLLGALLGYLAALWLLSWNTNGLIQSNWGRAILIICFVVVGVILIAFLERPMFVIASAFIGSFAIFCGVDVYVQTGFLEMVNSLLHAKSLDLVTNASSQLRGMLGGCLGLAIVGCLIQWCCIRRDSVKYVVWRERHPYGGGWTRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N250</accession>
    <name>A0A1C7N250_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Shugoshin C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_08842</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000720">
        <property type="protein sequence ID" value="OBZ83107.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N250"/>
    <dbReference type="InParanoid" id="A0A1C7N250"/>
    <dbReference type="OrthoDB" id="2283630at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="57"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="5"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="63"/>
            <end position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ83107.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="125" mass="14220" checksum="596B10B19AD9FF10" modified="2016-11-30" version="1">MPGLLAKYQEQNAEIIRNNIKLNERIAILESVISQLQQENLQLRMENIRKNRKKKYAALMHPKAPKSKSNLKSKTKDTPVIPTSSEQPVVLSQKRSCTTKPISYVLPSTKSKLRKGDPFTFGNDN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N337</accession>
    <name>A0A1C7N337_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">60S acidic ribosomal protein P0</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">rpp0_0</name>
        <name evidence="5" type="ORF">A0J61_08404</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uL10 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000643">
        <property type="protein sequence ID" value="OBZ83545.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N337"/>
    <dbReference type="STRING" id="101091.A0A1C7N337"/>
    <dbReference type="InParanoid" id="A0A1C7N337"/>
    <dbReference type="OrthoDB" id="10259902at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022625">
        <property type="term" value="C:cytosolic large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070180">
        <property type="term" value="F:large ribosomal subunit rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002181">
        <property type="term" value="P:cytoplasmic translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000027">
        <property type="term" value="P:ribosomal large subunit assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05795">
        <property type="entry name" value="Ribosomal_P0_L10e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.1730:FF:000002">
        <property type="entry name" value="60S acidic ribosomal protein P0"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1730">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050323">
        <property type="entry name" value="Ribosomal_protein_uL10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001790">
        <property type="entry name" value="Ribosomal_uL10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040637">
        <property type="entry name" value="Ribosomal_uL10-like_insert"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043141">
        <property type="entry name" value="Ribosomal_uL10-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45699">
        <property type="entry name" value="60S ACIDIC RIBOSOMAL PROTEIN P0"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45699:SF3">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN UL10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00466">
        <property type="entry name" value="Ribosomal_L10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17777">
        <property type="entry name" value="RL10P_insert"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160369">
        <property type="entry name" value="Ribosomal protein L10-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 5" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Large ribosomal subunit protein uL10-like insertion" evidence="4">
        <location>
            <begin position="108"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="155"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008889"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF17777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OBZ83545.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="155" mass="16963" checksum="F563023813DA1351" modified="2016-11-30" version="1" fragment="single">MSKRENKALYFQKLNNYLESYQSIFIVNVDNVSSNQMHQIRVALRGEAVVLMGKNTMVRRALKGLIVARPELEKLLNFVKGNIGFVFTNGDLKDIREKIVSNRVAAPARAGAVAPSDVTVPAGNTGMEPGKTSFFQALGIPTKIARGTIEIVSDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N3G3</accession>
    <name>A0A1C7N3G3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Ribosome assembly protein 3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">A0J61_08777</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Required for efficient biogenesis of the 60S ribosomal subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
            <location evidence="2">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the RSA3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000709">
        <property type="protein sequence ID" value="OBZ83176.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N3G3"/>
    <dbReference type="STRING" id="101091.A0A1C7N3G3"/>
    <dbReference type="InParanoid" id="A0A1C7N3G3"/>
    <dbReference type="OrthoDB" id="69550at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030687">
        <property type="term" value="C:preribosome, large subunit precursor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000027">
        <property type="term" value="P:ribosomal large subunit assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051898">
        <property type="entry name" value="Ribosome_Assembly_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028217">
        <property type="entry name" value="Rsa3_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28127">
        <property type="entry name" value="RIBOSOME ASSEMBLY PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28127:SF1">
        <property type="entry name" value="RIBOSOME ASSEMBLY PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14615">
        <property type="entry name" value="Rsa3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="5" id="KW-0690">Ribosome biogenesis</keyword>
    <feature type="domain" description="Ribosome-assembly protein 3 C-terminal" evidence="9">
        <location>
            <begin position="114"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="42"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="42"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="61"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="101"/>
            <end position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006256"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00015339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF14615"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OBZ83176.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="167" mass="19208" checksum="3CA8A87F303CDE68" modified="2016-11-30" version="1">MAPAGKKRNAKAQVNPKPAKAIRKQEDEVSLKMACNNDLFENLDEEMDPEEVEDYMHQLEENEGSDQEDLLDQASIEEEEKEEEEEEEEEEEEEENKEEQVSTPSEQQSVAKRFRDAYMTKVTQAFGSDLDQIRQEPTLNGPRLNILIDSLEAGIDIFSSLEQEIEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N444</accession>
    <name>A0A1C7N444_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Transcriptional repressor Tup1 N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">A0J61_08541</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000668">
        <property type="protein sequence ID" value="OBZ83409.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N444"/>
    <dbReference type="STRING" id="101091.A0A1C7N444"/>
    <dbReference type="InParanoid" id="A0A1C7N444"/>
    <dbReference type="OrthoDB" id="3253044at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.340">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013890">
        <property type="entry name" value="Tscrpt_rep_Tup1_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08581">
        <property type="entry name" value="Tup_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Transcriptional repressor Tup1 N-terminal" evidence="5">
        <location>
            <begin position="16"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="92"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="49"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="4">
        <location>
            <begin position="100"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="4">
        <location>
            <begin position="154"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="189"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="4">
        <location>
            <begin position="207"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="217"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF08581"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OBZ83409.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="217" mass="23795" checksum="E8EC3B6BB9837499" modified="2016-11-30" version="1" fragment="single">MSVYNHRPMVPAPQSRVVEMLDSIRGEFDQLAQELYLCKSQRDDFELKMNQQISEMNSFQQSLLELERTQQSQKKHYEDEIARLRQQIEARGGNAGHPSMPLPGHPQPPHQSSHQPPPPNIGPGSNYFGGIMNAHGNQAPPGLVAPPQMSDQPPNGPPPHGPYPSSQPPPSSTGSSSGYNQPPPPPPNSGYNQSPRGMHTPPTSAHPQPPPSQRQQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N482</accession>
    <name>A0A1C7N482_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">CCR4-NOT transcription complex subunit 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">A0J61_08503</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000661">
        <property type="protein sequence ID" value="OBZ83449.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N482"/>
    <dbReference type="STRING" id="101091.A0A1C7N482"/>
    <dbReference type="InParanoid" id="A0A1C7N482"/>
    <dbReference type="OrthoDB" id="2236331at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030015">
        <property type="term" value="C:CCR4-NOT core complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000932">
        <property type="term" value="C:P-body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0060090">
        <property type="term" value="F:molecular adaptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017148">
        <property type="term" value="P:negative regulation of translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000288">
        <property type="term" value="P:nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.840:FF:000003">
        <property type="entry name" value="Transcription regulator"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.840">
        <property type="entry name" value="CCR4-NOT transcription complex subunit 1 TTP binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032191">
        <property type="entry name" value="CNOT1_CAF1_bind"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032194">
        <property type="entry name" value="CNOT1_HEAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032193">
        <property type="entry name" value="CNOT1_TTP_bind"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038535">
        <property type="entry name" value="CNOT1_TTP_bind_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040398">
        <property type="entry name" value="Not1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13162">
        <property type="entry name" value="CCR4-NOT TRANSCRIPTION COMPLEX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13162:SF8">
        <property type="entry name" value="CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16415">
        <property type="entry name" value="CNOT1_CAF1_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16418">
        <property type="entry name" value="CNOT1_HEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16417">
        <property type="entry name" value="CNOT1_TTP_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CCR4-NOT transcription complex subunit 1 HEAT repeat" evidence="4">
        <location>
            <begin position="305"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="domain" description="CCR4-NOT transcription complex subunit 1 TTP binding" evidence="3">
        <location>
            <begin position="429"/>
            <end position="594"/>
        </location>
    </feature>
    <feature type="domain" description="CCR4-NOT transcription complex subunit 1 CAF1-binding" evidence="2">
        <location>
            <begin position="638"/>
            <end position="712"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="713"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF16415"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF16417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF16418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OBZ83449.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="713" mass="81242" checksum="E5ADAA1B9875B392" modified="2016-11-30" version="1" fragment="single">MSSESDISNSSTPNKQRITTKSQKASLIRIVKAQITLLTSNLNNDNFAKKSTDINNLIETHGEEIREHLIRYILSDVYKQCLIQNTHSPHVRLLRQHTNFSKTAESATNLRAMTSFGLALEQFCKSDISTQMDLSDLFDKLEFDSLDRVIFSTALFSKAKLRIVEQAKRIYTSHIQNAISILTTAIEKLPENALQYFLNAIAHALSDDSHQFNFEQLRIITALASQRCTNKSVIEQVQSLIALKANPEKLANDQQFKQSIIEMYTSNPSSVTRILDLVKELNVSKYPYDINHAGKLKSNIFDQAFPSILESLPLFLALDLACLADSQKHLHLESWLRERLSNQQQPQRDVCAGQCLEFLNQKIFTELQRQAGTSDTLSVPLSSEAMIVLLKVLAESHLSPQFIDAIKEIHNRCLQTFPKMIDMKAQATSAAIGAEVSFKPEIEEEANMYYERIYNGEMSIDAMIDLLKRLSISKDAKEQDIYACMIHNLFDEYAFFPKYPEKELSITSTLFGLLIQHQIIAYVPLGIALRYVLDALRNPVGSKMFNFGIRALEQFQSRLTEWPQYCTHLLQIPHFVHSQPKLATFIQQIMARQHLNSSDDISDQNENNKNHLVNTKSPIPFTCIHVPSVPKQMDEVAYSEPSSSIKDKVLFTINNLALNNLEAKIADLKEVLQPAYFKWFSNYLVVKRASSELNNHELYVLMLDLFDSKLLHS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N4D5</accession>
    <name>A0A1C7N4D5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_07952</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000571">
        <property type="protein sequence ID" value="OBZ83995.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N4D5"/>
    <dbReference type="InParanoid" id="A0A1C7N4D5"/>
    <dbReference type="OrthoDB" id="2283184at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="29"/>
            <end position="40"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ83995.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="127" mass="14335" checksum="97BB2976976CE1F6" modified="2016-11-30" version="1">MERQRQEVESGDLKQIQRDHQLSEKRKSTSSSNSSVRPPSLLERRQSNNQNAMKSEEITPMPTGAERMAALRDLGATFEEGRKSIAKVATPTETVVPSFVDSDHLEQILHKKQKKNLSDTCDETKVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N4P7</accession>
    <name>A0A1C7N4P7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Heat shock protein 78, mitochondrial</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">hsp78</name>
        <name evidence="11" type="ORF">A0J61_07832</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the ClpA/ClpB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000553">
        <property type="protein sequence ID" value="OBZ84115.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N4P7"/>
    <dbReference type="FunCoup" id="A0A1C7N4P7">
        <property type="interactions" value="119"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N4P7"/>
    <dbReference type="InParanoid" id="A0A1C7N4P7"/>
    <dbReference type="OrthoDB" id="47330at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051787">
        <property type="term" value="F:misfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034605">
        <property type="term" value="P:cellular response to heat"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042026">
        <property type="term" value="P:protein refolding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050821">
        <property type="term" value="P:protein stabilization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043335">
        <property type="term" value="P:protein unfolding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd00009">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd19499">
        <property type="entry name" value="RecA-like_ClpB_Hsp104-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000120">
        <property type="entry name" value="ATP-dependent chaperone ClpB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000025">
        <property type="entry name" value="ATP-dependent Clp protease subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000010">
        <property type="entry name" value="Chaperone clpB 1, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019489">
        <property type="entry name" value="Clp_ATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001270">
        <property type="entry name" value="ClpA/B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018368">
        <property type="entry name" value="ClpA/B_CS1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028299">
        <property type="entry name" value="ClpA/B_CS2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041546">
        <property type="entry name" value="ClpA/ClpB_AAA_lid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050130">
        <property type="entry name" value="ClpA_ClpB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11638">
        <property type="entry name" value="ATP-DEPENDENT CLP PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11638:SF176">
        <property type="entry name" value="HEAT SHOCK PROTEIN 78, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07724">
        <property type="entry name" value="AAA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17871">
        <property type="entry name" value="AAA_lid_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10431">
        <property type="entry name" value="ClpB_D2-small"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00300">
        <property type="entry name" value="CLPPROTEASEA"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM01086">
        <property type="entry name" value="ClpB_D2-small"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00870">
        <property type="entry name" value="CLPAB_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00871">
        <property type="entry name" value="CLPAB_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 6" id="KW-0143">Chaperone</keyword>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="11" id="KW-0346">Stress response</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="9">
        <location>
            <begin position="121"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="domain" description="AAA+ ATPase" evidence="9">
        <location>
            <begin position="522"/>
            <end position="665"/>
        </location>
    </feature>
    <feature type="domain" description="Clp ATPase C-terminal" evidence="10">
        <location>
            <begin position="691"/>
            <end position="776"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="778"/>
            <end position="825"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="335"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="796"/>
            <end position="807"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="816"/>
            <end position="825"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008675"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU004432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM01086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="OBZ84115.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="825" mass="92514" checksum="A529DBA17FEE5627" modified="2016-11-30" version="1">MIRLPQRCISLASKRQLSTLPKRTAVLAGPVKTSLVTTALMKPRYLAVNYPVIKRFYNGGTPGQGGFRMNPNQAQEEKKPLEQFGIDLTAMAEKGKLDPVIGRDEEIRRTLEENNSLARRTKNNPVLIGEAGVGKTAIAEGLAQRIVANEVPESIKGKRVVALDLGALVAGAKYRGEFEDRLKGVLKEVSESEGSIILFIDEIHTLLGLGKSEGAMDAGNLLKPALARGQLRCVGATTIDEYRKYIMQDPALARRFQQVMVEEPTVQDTISILRGLKERYEVHHGVRISDAAIVAAALHSHRYIADRFLPDKAIDLLDEACSKLRLQQESKPEALENLDRQIMTAQIELESLRKETDVMSVERRQKLEQEVKEKQKESERLTAVWNEERQKIEEIKRVKEDLEKARNDLEQAQRNGNYQRASELRYGVIPNLEKQLPTDNNSEEEENGESLIHERVTSNDIARVVSHMTGIPVRNLMKGEREKLLHMEDVMSERVVGQDEAIRAVAEAVRLSRAGLQNPSKPIASFLFLGPTGVGKTELCKTIAKFLFDTEHAIVRVDMSEYMEKFSVSRLIGSPPGYVGHEEGGELTEAVRRRPYAVVLLDEMEKAHRDVSNILLQVLDDGVLTDTKGRKIDFRNTIIIMTSNLGAEALVSDHSQEVSPHAKESVMEAVKHSFAPEFINRIDEMVIFNRLSKKALRDIVDVRIKEVEERTADRRIKMDISLEARDWLGERGYDPAYGARPLNRLIQKKLLNPLARLLIDGGIRTGETAKVTVETLPNGETDLHVQRNHPAGSKASSEEEKLLEEHMAPVGDEEGIDTKKENDVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N531</accession>
    <name>A0A1C7N531_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Putative histone deacetylase complex subunit cti6</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">cti6</name>
        <name evidence="6" type="ORF">A0J61_08201</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000610">
        <property type="protein sequence ID" value="OBZ83749.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N531"/>
    <dbReference type="FunCoup" id="A0A1C7N531">
        <property type="interactions" value="48"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N531"/>
    <dbReference type="InParanoid" id="A0A1C7N531"/>
    <dbReference type="OrthoDB" id="79252at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033698">
        <property type="term" value="C:Rpd3L complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070210">
        <property type="term" value="C:Rpd3L-Expanded complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061188">
        <property type="term" value="P:negative regulation of rDNA heterochromatin formation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061186">
        <property type="term" value="P:negative regulation of silent mating-type cassette heterochromatin formation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd15550">
        <property type="entry name" value="PHD_MLL5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053051">
        <property type="entry name" value="HDAC_complex_subunit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019786">
        <property type="entry name" value="Zinc_finger_PHD-type_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001965">
        <property type="entry name" value="Znf_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47793">
        <property type="entry name" value="HISTONE DEACETYLASE COMPLEX SUBUNIT CTI6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47793:SF1">
        <property type="entry name" value="HISTONE DEACETYLASE COMPLEX SUBUNIT CTI6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20826">
        <property type="entry name" value="PHD_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00249">
        <property type="entry name" value="PHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01359">
        <property type="entry name" value="ZF_PHD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Zinc finger PHD-type" evidence="5">
        <location>
            <begin position="41"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="157"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="343"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="26"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="194"/>
            <end position="205"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OBZ83749.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="362" mass="40821" checksum="A68E16466336E822" modified="2016-11-30" version="1">MVAHSSKRSGRQSVGRKKRQPRRRSQSTSDENSTDSSSVTRCICGHTHSLGLMVQCDKCEVWQHCECMGLEPPDIPDQYYCEQCKPENHKHIRYHHGRSKRYYVASEKSPKKRTTLNSREASMSLEDVLAAKSALEMYESHMHDDPLGSLTEEPVMEEEQDMKPMASPESEPQSIKPKPSVKRKTRPTDEKIKKGLRPHKRKTRSRTATPIRELSPATPECDEEACQAADSISLALFDYFSPQARAASPPAKTRPPHARMSLSDMNRRANQILEYISSIQVEMASKTEDHAGHGTSHDDSCSLSSASTLPLDHVIQTEQTSMDIMDMLTRKLIQFQRRFGPQHPIEISEDGPDSFSNITACS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N570</accession>
    <name>A0A1C7N570_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 7">Nucleolar GTP-binding protein 2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">NOG2</name>
        <name evidence="10" type="ORF">A0J61_08151</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 7">GTPase that associates with pre-60S ribosomal subunits in the nucleolus and is required for their nuclear export and maturation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 7">Nucleus</location>
            <location evidence="2 7">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the TRAFAC class YlqF/YawG GTPase family. NOG2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000602">
        <property type="protein sequence ID" value="OBZ83799.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N570"/>
    <dbReference type="FunCoup" id="A0A1C7N570">
        <property type="interactions" value="496"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N570"/>
    <dbReference type="InParanoid" id="A0A1C7N570"/>
    <dbReference type="OrthoDB" id="444945at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005654">
        <property type="term" value="C:nucleoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030687">
        <property type="term" value="C:preribosome, large subunit precursor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070180">
        <property type="term" value="F:large ribosomal subunit rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:2000200">
        <property type="term" value="P:regulation of ribosomal subunit export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000055">
        <property type="term" value="P:ribosomal large subunit export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd01858">
        <property type="entry name" value="NGP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000559">
        <property type="entry name" value="Nuclear/nucleolar GTPase 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1580.10:FF:000001">
        <property type="entry name" value="Nucleolar GTP-binding protein 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1580.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030378">
        <property type="entry name" value="G_CP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024929">
        <property type="entry name" value="GNL2_CP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006073">
        <property type="entry name" value="GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023179">
        <property type="entry name" value="GTP-bd_ortho_bundle_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012971">
        <property type="entry name" value="NOG2_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050755">
        <property type="entry name" value="TRAFAC_YlqF/YawG_RiboMat"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11089">
        <property type="entry name" value="GTP-BINDING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11089:SF9">
        <property type="entry name" value="NUCLEOLAR GTP-BINDING PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01926">
        <property type="entry name" value="MMR_HSR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08153">
        <property type="entry name" value="NGP1NT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00326">
        <property type="entry name" value="GTP1OBG"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51721">
        <property type="entry name" value="G_CP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="4 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6 7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CP-type G" evidence="9">
        <location>
            <begin position="206"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="530"/>
            <end position="672"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="574"/>
            <end position="606"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU364023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51721"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OBZ83799.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="672" mass="76444" checksum="5C074591AAF1B30B" modified="2016-11-30" version="1">MGQYKKEKQRVQRDKAGGDDRAKNIRLKGENFYRDAKKIKYINMLKGGKAIRDSQGRIVKAADFQSSEVKTARVAPNRKWFGNTRVIGQKALEDFRESLAAKVDDPYQVLLKQNKLPMSLLQDSTKHTRMHILETDSFGNTFGSKAQRKKPKLNIGSMEEMMSQVDDTHDTYKSEKDSSLLANKESDYSEAGRAWYLQAGQSKRIWNELYKVIDSSDVIIHVLDARDPIGTRCHNVEKFIRKEKPHKQLIFVLNKCDLVPTWSTARWVSHLSKFAPTLAFHASINNSFGKGSLIQLLRQFSSLHSDRKQISVGFIGYPNTGKSSIINTLKNKKVCQVAPIPGETKVWQYITLMKRIYLIDCPGVVPPNVDDNEVDIILKGSVRVEKMESPEDTIPTILERVRHEYLKRTYGLTSWVDHTDFLEQIARKTGKLLKKGEADVHNVSIMVLNDWLRGRIPFYVPPPESVEPLTEEQKDEKKNKIGVEQMFAKINVTAEYMEDDLANNAQLIAEERAKAKAKKEEEEAAAAAAVAAKDKSKKKKKATPASEAEVTDWDEVFESVVGEEGPVVKAPVIEGEEEEEDEEEEVDSELELTDNGEDEEEEEEEEQPVKKTKVNNNETEVDRKNKKVGVHYYETANVKNRNRNKVKPDESKKKVLHSRLKGSASGSKRKRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N5N8</accession>
    <name>A0A1C7N5N8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">A0J61_07494</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000508">
        <property type="protein sequence ID" value="OBZ84452.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N5N8"/>
    <dbReference type="InParanoid" id="A0A1C7N5N8"/>
    <dbReference type="OrthoDB" id="9451547at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051149">
        <property type="entry name" value="Spindly/BICDR_Dynein_Adapter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32123">
        <property type="entry name" value="BICD FAMILY-LIKE CARGO ADAPTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32123:SF9">
        <property type="entry name" value="PROTEIN SPINDLY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="404"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OBZ84452.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="438" mass="50904" checksum="E19658D5A84599FC" modified="2016-11-30" version="1">MISTKECLQPPPSPTLSATSSISSWFQKSPSELIPMLKNAYTTIRDKEKDLRLAAEIGKSLLENNIVLKSNYDDLLSQSIYPTPSSSYTLSDKEDIIFLPTHTTREAKIEILEKANTDLSAQLELTVQHQQKKERLHKRKEHEMETEIYLLKSSLDHATIQLQQMKEKTLSKEGNPKQSVLPEDNELLHEKIKELKLENDQVYHSKLAVEEKLMKTLHDLRLLKQQVDQFQFTLHDHEQLQKSFEAQQLHIQQLKSSLEEHRQLLSQLRDHEIMXKEEQQNQNLLSELHHASPREDQDEDDDEEENDKLLASILLKAGVVERDAIDDALSLIGRLENEYDHQRYLKENGHINKEESFLETEKTHTMLIKSDKQLVNVTHSPSTCPPSPGLVGTLQRMMKRILYFTWRWFRFTLIMTIAVFLSLKEGPPSPVKYPRRLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N5R4</accession>
    <name>A0A1C7N5R4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">inositol-3-phosphate synthase</fullName>
            <ecNumber evidence="6">5.5.1.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="primary">ino1</name>
        <name evidence="17" type="ORF">A0J61_07476</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>D-glucose 6-phosphate = 1D-myo-inositol 3-phosphate</text>
            <dbReference type="Rhea" id="RHEA:10716"/>
            <dbReference type="ChEBI" id="CHEBI:58401"/>
            <dbReference type="ChEBI" id="CHEBI:61548"/>
            <dbReference type="EC" id="5.5.1.4"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="4">Polyol metabolism; myo-inositol biosynthesis; myo-inositol from D-glucose 6-phosphate: step 1/2.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the myo-inositol 1-phosphate synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.5.1.4" evidence="6"/>
    <dbReference type="EMBL" id="LUGH01000506">
        <property type="protein sequence ID" value="OBZ84473.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N5R4"/>
    <dbReference type="STRING" id="101091.A0A1C7N5R4"/>
    <dbReference type="InParanoid" id="A0A1C7N5R4"/>
    <dbReference type="OrthoDB" id="2887at2759"/>
    <dbReference type="UniPathway" id="UPA00823">
        <property type="reaction ID" value="UER00787"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004512">
        <property type="term" value="F:inositol-3-phosphate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006021">
        <property type="term" value="P:inositol biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008654">
        <property type="term" value="P:phospholipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000069">
        <property type="entry name" value="Inositol-3-phosphate synthase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000204">
        <property type="entry name" value="Inositol-3-phosphate synthase 1-B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.360.10:FF:000055">
        <property type="entry name" value="Putative myo-inositol-1-phosphate synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002587">
        <property type="entry name" value="Myo-inos-1-P_Synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013021">
        <property type="entry name" value="Myo-inos-1-P_Synthase_GAPDH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11510">
        <property type="entry name" value="MYO-INOSITOL-1 PHOSPHATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01658">
        <property type="entry name" value="Inos-1-P_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07994">
        <property type="entry name" value="NAD_binding_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55347">
        <property type="entry name" value="Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9" id="KW-0398">Inositol biosynthesis</keyword>
    <keyword evidence="13" id="KW-0413">Isomerase</keyword>
    <keyword evidence="8" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="11" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="10" id="KW-0520">NAD</keyword>
    <keyword evidence="12" id="KW-0594">Phospholipid biosynthesis</keyword>
    <keyword evidence="14" id="KW-1208">Phospholipid metabolism</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Myo-inositol-1-phosphate synthase GAPDH-like" evidence="16">
        <location>
            <begin position="388"/>
            <end position="501"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="45"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="15">
        <location>
            <begin position="68"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="17">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001911"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00010813"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00012125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022550"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF01658"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="OBZ84473.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="590" mass="65498" checksum="862182D8F016CF97" modified="2016-11-30" version="1" fragment="single">KKRNQTLFVFFCEARILKETLLFFLPPKRLQISFLQHTTHTEDIKGAVIDPKNQPKNQEPMAPPNADLSHSASSNANHGVPSPLFKVNSPNVQYTDEHIISKYVYQNTLVTRQPDGTLIAEPTETVYEFKTERTVPKVGVMMVGWGGNNGSTLTASILAHKNNLTWRTKSGIQKPNYYGSVTQSSTVRLGVDAKGTDVYVPLSEMLPLVHPTDLVLGGWDISGKNLAESMERAQVLEYDLQRQVYDEMAKMVPLPSIYYPDFIAANQEDRADNLIPGSDKRAHVNQIRKDIRDFKSAHQLDKIIVLWTANTERFAELIDGVNDTADNFLAAVEASHDEIAPSSIFALACIEEGAPFINGSPQNTFVPGLIQLAERHRAFIGGDDFKSGQTKMKSALVDFLVNAGIKPVAITSYNHLGNNDGKNLSSHKQFRSKEISKSTVVDDMVAANHLLYAKNEHPDHTVVIKYVPSVGDSKRALDEYECDIFMGGRQSISMYNVCEDSLLASPLIIDLVVMAELMTRIEYKSAEMTKFSTFHSVLSILSYMLKAPMVTPGTPVVNALGRQRSAIENIFRAAVGLSANNEMGLEHKIW</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N5W1</accession>
    <name>A0A1C7N5W1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Hexose transporter 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">KHT2_1</name>
        <name evidence="11" type="ORF">A0J61_07920</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000567">
        <property type="protein sequence ID" value="OBZ84029.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N5W1"/>
    <dbReference type="FunCoup" id="A0A1C7N5W1">
        <property type="interactions" value="330"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N5W1"/>
    <dbReference type="InParanoid" id="A0A1C7N5W1"/>
    <dbReference type="OrthoDB" id="4142200at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005351">
        <property type="term" value="F:carbohydrate:proton symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000134">
        <property type="entry name" value="MFS sugar transporter protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050360">
        <property type="entry name" value="MFS_Sugar_Transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00879">
        <property type="entry name" value="SP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48022:SF2">
        <property type="entry name" value="PLASTIDIC GLUCOSE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00171">
        <property type="entry name" value="SUGRTRNSPORT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00217">
        <property type="entry name" value="SUGAR_TRANSPORT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="45"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="91"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="118"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="144"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="177"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="212"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="297"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="330"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="364"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="407"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="442"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="471"/>
            <end position="491"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="10">
        <location>
            <begin position="48"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="12"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="OBZ84029.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="508" mass="55531" checksum="F6A2A4C95174CB59" modified="2016-11-30" version="1">MSTGIEAGQMENKGHEKKSYGGVDADKSSSSIMDGIEPPKFRKSVYFSALIAAIGGFVCGYDTGAISGILAMPTFQAHFFTEENLNYLQGLLLALFLMTAAIGSFLFGFLCDRFSRKYTIVGSAVVFTVGILLEIIGANFGVLLAGRLIAGFGSGLMGSSIPLYHSEIAPPDIRGRLISLFTLMSSFGQVVGYFVTFGTSYVTSDWSWRGPWLLHIIVCVIVGITVTFLPFSPRWLIDKGRHEEAKAVLSELHQVPTDHPIVLNEYNDISSEIEFERSQGDRTYIELFQGHNLKRTLISFFISIGTSFTGSVAIWYYAPQIIQNTGMGDASVSIATTGGTGIFSFLASFVSLQFCIDQVGRRALFLIGAAIMAVSMFVVGAMFQAYAIVDSESFAVTIANTNARNTIIAFLYIFVGTFAFSWGSVSYVYPAEIFNMRTRAKGLALTYGLNWSFSILITYCVPLFIAQTTSGVYFFFGACCCICFVGCCFIPETKGKTLEQMEYVFGAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N679</accession>
    <name>A0A1C7N679_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Mitochondrial oxaloacetate transport protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">OAC1</name>
        <name evidence="13" type="ORF">A0J61_07327</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000487">
        <property type="protein sequence ID" value="OBZ84633.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N679"/>
    <dbReference type="FunCoup" id="A0A1C7N679">
        <property type="interactions" value="91"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N679"/>
    <dbReference type="InParanoid" id="A0A1C7N679"/>
    <dbReference type="OrthoDB" id="6703404at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034658">
        <property type="term" value="F:isopropylmalate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901239">
        <property type="term" value="F:malonate(1-) transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015131">
        <property type="term" value="F:oxaloacetate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015116">
        <property type="term" value="F:sulfate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051508">
        <property type="entry name" value="Mito_Carrier_Antiporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45928">
        <property type="entry name" value="RE38146P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45928:SF1">
        <property type="entry name" value="RE38146P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 10 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 10 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 11" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="21"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="129"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="10">
        <location>
            <begin position="20"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="10">
        <location>
            <begin position="128"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="10">
        <location>
            <begin position="230"/>
            <end position="322"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU000488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="OBZ84633.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="328" mass="35919" checksum="A22FBF60AF297524" modified="2016-11-30" version="1">MSAIQESTHQLNQAPRSRTKDTAVGFVIGGLAACGAVTFTNPWEVVKTRLQLQGELVRAGALSEGARPYHNSFQALKVVFQHEGLQGAQRGLSIAYFYQICLNGSRLGLYEPVLNKIKNTLHLKSESSLLAASVFSGAFAGVVGAVLGSPLYLIKTRRQSFSPVFKNIGYQHEMGSAVNALSQIYRTEGIRGLYRGADAAMMRAGVGSAVQMPTYMLGKDILLKRFGFPDTFSTHFATSMFTGVLVCLAMNPFDVISTRMYNQGVDPKTGKGLLYNGPMDCAVKMVKIEGVRGLYKGFLAHYLRIGPHTTLMFVFMEQLKKVYNNNFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N909</accession>
    <name>A0A1C7N909_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_08118</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000597">
        <property type="protein sequence ID" value="OBZ83834.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N909"/>
    <dbReference type="InParanoid" id="A0A1C7N909"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ83834.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="151" mass="17137" checksum="B4B761AE8156B086" modified="2016-11-30" version="1">MMKFDSLRNNALTELKQSGVHSRTEFASFALEKKSEIYGKSRQMPSALRAEITDILKKYHDDDLEKLEKLTLLKLKNKGINAIIVKALLLLFIKTLFACDALRDCRQDFLIEANHQKPLTKVVGEIKGEASGLEELAVDSYRLGVFGRHML</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N951</accession>
    <name>A0A1C7N951_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_06289</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000373">
        <property type="protein sequence ID" value="OBZ85653.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N951"/>
    <dbReference type="InParanoid" id="A0A1C7N951"/>
    <dbReference type="OrthoDB" id="2241330at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="58"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="101"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="161"/>
            <end position="185"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ85653.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="197" mass="22016" checksum="6E3507969EF9900D" modified="2016-11-30" version="1">MSLCTYKMMPLHLIQALHIWNSLIGVILFGLLIGTAKNIKVFITGGAEIAGFGNFNTFAYPATFVYMFIPVIGSTVYSMILAFDSSPKYKAWLPSKTMRTTIAFFALTNLLAAMLPVIQGADVMSDGSAIECAWTDYMQWKTIYNAPDIFPWVTKMDLACAIFKACDAFCWILSIGWTVQLFLYVRAARSAKFYVSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N9B8</accession>
    <name>A0A1C7N9B8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_06215</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000365">
        <property type="protein sequence ID" value="OBZ85733.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N9B8"/>
    <dbReference type="InParanoid" id="A0A1C7N9B8"/>
    <dbReference type="OrthoDB" id="2595509at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="59"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="59"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="85"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="110"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="173"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="226"/>
            <end position="248"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ85733.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="248" mass="27699" checksum="71372073F2FEA276" modified="2016-11-30" version="1">MSLNSRYRERKYNTSENERLLLALSQPVQAWDKKWAQLSTAKTLQTYKWTKSDRVIQFEPDEESEEEPEPMELEQTAQVEPSEIATVEPLAATATATTEMTEAENKANLEKTQNNQGQTAFLSDESSIPGGPSTLITNKPLAALQKEDEDEQRSQTPKLSDISDDEQNKQNVDEDEDNDIDSINDASKHPALAPHAQARLTDDDFTDSTAATPQTEDTPMMEDMSAANQGSHPLSQEIQQDSLMDQQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N9C1</accession>
    <name>A0A1C7N9C1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein y4xN</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_06233</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000367">
        <property type="protein sequence ID" value="OBZ85715.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N9C1"/>
    <dbReference type="STRING" id="101091.A0A1C7N9C1"/>
    <dbReference type="InParanoid" id="A0A1C7N9C1"/>
    <dbReference type="OrthoDB" id="2117718at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016881">
        <property type="term" value="F:acid-amino acid ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019290">
        <property type="term" value="P:siderophore biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007310">
        <property type="entry name" value="Aerobactin_biosyn_IucA/IucC_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022770">
        <property type="entry name" value="IucA/IucC-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037455">
        <property type="entry name" value="LucA/IucC-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34384">
        <property type="entry name" value="L-2,3-DIAMINOPROPANOATE--CITRATE LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34384:SF5">
        <property type="entry name" value="L-2,3-DIAMINOPROPANOATE--CITRATE LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06276">
        <property type="entry name" value="FhuF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04183">
        <property type="entry name" value="IucA_IucC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aerobactin siderophore biosynthesis IucA/IucC N-terminal" evidence="1">
        <location>
            <begin position="196"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="domain" description="Aerobactin siderophore biosynthesis IucA/IucC-like C-terminal" evidence="2">
        <location>
            <begin position="452"/>
            <end position="574"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF04183"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF06276"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ85715.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="628" mass="70828" checksum="2D6367F14F63C8B2" modified="2016-11-30" version="1">MPVASTQFDKNEHYASFATTSRLVACLTSESLVPVYLVPSKRQDLVGLCLLLRPTVCEEDKVPEKVSVQDILAVVPLRGLPIINETCAKWNGILCPRIDLVDNLDMEPHIYSINTTQAQNGENAAHQVLKTVISDATEFSLVDGYDAVSMWDRFAADRQVNAKLREQIGQELGSSILFQKYTYDYPKKLPGLNSSTIAWEQAVVEGHATHPMHKARKSFPPMKTLSPGSYDLDHPKVRLVGVPRSSAILRGDYENLSNKLVDALFEAGVGQQNVKAERSKYDADYVYIAIHELQLPNVEQKFSDALIFPEAYSINVEALASLRSVARPDILPGLSVKLCLGIKISSALRTVTPFTTYFGPGFSENVVPKLTYDASVLAIERELGTITYNIEDTDIAKHCSSVIREALEYDPQYKDDLFIPCGVLVEKIQRPDTDETMVTHVWGLDTEEKRVEFLNRYVEFALRAFLPPCLENGVAFEAHGQNTLARFDRKTGQLKGFVIRDFGGVKVHNETLKKSTGAELDILPDSCVEAHSLDEVVKLLYHTLFHCQFQRLIRVLNLHYNGVGWELVRQHMTRMIPREHPMWSMFMAPAKVPGKCLVRMKIDELYRDYIYRPVPNMINFKPQQIPQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N9L1</accession>
    <name>A0A1C7N9L1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 9">Imidazoleglycerol-phosphate dehydratase</fullName>
            <ecNumber evidence="4 9">4.2.1.19</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">HIS3</name>
        <name evidence="10" type="ORF">A0J61_06203</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 9">
            <text>D-erythro-1-(imidazol-4-yl)glycerol 3-phosphate = 3-(imidazol-4-yl)-2-oxopropyl phosphate + H2O</text>
            <dbReference type="Rhea" id="RHEA:11040"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:57766"/>
            <dbReference type="ChEBI" id="CHEBI:58278"/>
            <dbReference type="EC" id="4.2.1.19"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 9">Amino-acid biosynthesis; L-histidine biosynthesis; L-histidine from 5-phospho-alpha-D-ribose 1-diphosphate: step 6/9.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 9">Belongs to the imidazoleglycerol-phosphate dehydratase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.19" evidence="4 9"/>
    <dbReference type="EMBL" id="LUGH01000364">
        <property type="protein sequence ID" value="OBZ85740.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N9L1"/>
    <dbReference type="FunCoup" id="A0A1C7N9L1">
        <property type="interactions" value="116"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N9L1"/>
    <dbReference type="InParanoid" id="A0A1C7N9L1"/>
    <dbReference type="OrthoDB" id="447729at2759"/>
    <dbReference type="UniPathway" id="UPA00031">
        <property type="reaction ID" value="UER00011"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004424">
        <property type="term" value="F:imidazoleglycerol-phosphate dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000105">
        <property type="term" value="P:L-histidine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd07914">
        <property type="entry name" value="IGPD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.230.40:FF:000004">
        <property type="entry name" value="Imidazoleglycerol-phosphate dehydratase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.230.40:FF:000001">
        <property type="entry name" value="Imidazoleglycerol-phosphate dehydratase HisB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.40">
        <property type="entry name" value="Imidazole glycerol phosphate dehydratase, domain 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00076">
        <property type="entry name" value="HisB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038494">
        <property type="entry name" value="IGPD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000807">
        <property type="entry name" value="ImidazoleglycerolP_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020565">
        <property type="entry name" value="ImidazoleglycerP_deHydtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_Su5_D2-typ_SF"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF002111">
        <property type="entry name" value="PRK00951.2-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF002114">
        <property type="entry name" value="PRK00951.2-4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23133:SF2">
        <property type="entry name" value="IMIDAZOLEGLYCEROL-PHOSPHATE DEHYDRATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23133">
        <property type="entry name" value="IMIDAZOLEGLYCEROL-PHOSPHATE DEHYDRATASE HIS7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00475">
        <property type="entry name" value="IGPD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="Ribosomal protein S5 domain 2-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00954">
        <property type="entry name" value="IGP_DEHYDRATASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00955">
        <property type="entry name" value="IGP_DEHYDRATASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="7 9" id="KW-0368">Histidine biosynthesis</keyword>
    <keyword evidence="8 9" id="KW-0456">Lyase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00016664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU000598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OBZ85740.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="198" mass="21580" checksum="62E55E80C944D58E" modified="2016-11-30" version="1">MSEARTATLERKTNETDIKVSINLDDKYDQKIHIDTGIGFLDHMYHALAKHGGWSLNLVCKGDLHIDDHHTAEDTGIALGMAFKQALGTPRGIKRFGSAFCPLDEALARSVVDISGRPFADINLDLRREMIGQLSTEMIPHVLESFAGAAGITLHVDVLKGKNDHHRAESAFKSLAVAIREAVTRTGTNDVPSTKGVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N9V1</accession>
    <name>A0A1C7N9V1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">A0J61_06563</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000402">
        <property type="protein sequence ID" value="OBZ85386.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N9V1"/>
    <dbReference type="STRING" id="101091.A0A1C7N9V1"/>
    <dbReference type="InParanoid" id="A0A1C7N9V1"/>
    <dbReference type="OrthoDB" id="2287938at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008889559" evidence="3">
        <location>
            <begin position="27"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="256"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="28"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="215"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="447"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="38"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="60"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="77"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="452"/>
            <end position="468"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OBZ85386.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="468" mass="48161" checksum="B37BACA5A4DECF5E" modified="2016-11-30" version="1">MKFSSIGKLSICLLIVLQIWIQVASAQSNSTAEDTEASTTKDTSVSSSKDTNASSKSGSDNTFSAQQVSNTDANVNSVQAQATTQESAAAAKTTESSAAAVTTEAPVVTTTKEEPITTTKAPATTTEAPAVTTTTEAPAVTTTTEAPAVITTTTEAPITTTTDAPVVITTTSNVVETTNAVPIITTDQPSSAIYSTESVITGFYPIYTSIGTASSSSVTQSSTSMPASKASTSSSPSATPSTSADNTDNNSNKAGVIAGSVVGAIVGIALIGGLVAWINRHGGCASRSNKRNKGGYTQDDYAIDMQPNDYNNHSAAAAAAAVGVGATAATINSTEPLSPFDNSRHYPANATYSNDPYGDYHESYSQGGYSQGAYSQEAFNNYGYYDPNVAAAGVAAAGAQSYGLAPAGYDSNRHEIPDNEMYGYNQAYQQPYSNMATPISAGNMSEYASHLPADKPNARDYGSKPNEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NA69</accession>
    <name>A0A1C7NA69_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">60S ribosomal protein L28</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">RPL28_1</name>
        <name evidence="7" type="ORF">A0J61_05927</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the universal ribosomal protein uL15 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000336">
        <property type="protein sequence ID" value="OBZ86015.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NA69"/>
    <dbReference type="FunCoup" id="A0A1C7NA69">
        <property type="interactions" value="475"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NA69"/>
    <dbReference type="InParanoid" id="A0A1C7NA69"/>
    <dbReference type="OrthoDB" id="61900at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022625">
        <property type="term" value="C:cytosolic large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.100.10.10:FF:000002">
        <property type="entry name" value="60S ribosomal protein L27a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.100.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01341">
        <property type="entry name" value="Ribosomal_uL15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030878">
        <property type="entry name" value="Ribosomal_uL15"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021131">
        <property type="entry name" value="Ribosomal_uL15/eL18"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036227">
        <property type="entry name" value="Ribosomal_uL15/eL18_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001196">
        <property type="entry name" value="Ribosomal_uL15_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11721">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L27A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11721:SF3">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN UL15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00828">
        <property type="entry name" value="Ribosomal_L27A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52080">
        <property type="entry name" value="Ribosomal proteins L15p and L18e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00475">
        <property type="entry name" value="RIBOSOMAL_L15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 7" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Large ribosomal subunit protein uL15/eL18" evidence="6">
        <location>
            <begin position="95"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="31"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="44"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007320"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003888"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00828"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OBZ86015.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="168" mass="18691" checksum="9049229165397EAA" modified="2016-11-30" version="1">MKTTAVSPYYPSYSQAAILTVNSCPTRLHHNRKKRGHVSAGHGRIGKHRKHPGGRGLAGGQHHHRINMDKYHPGYFGKVGMRHFHLKKNAYWRPVVNIDKLWTLAAEGAREQYKNTEKVPVIDALQNGYAKVLAKGTISQPVIVRTRFVSSLAEKKIKAAGGVVELIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NAK1</accession>
    <name>A0A1C7NAK1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">2-iminobutanoate/2-iminopropanoate deaminase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">yabJ</name>
        <name evidence="2" type="ORF">A0J61_06294</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the RutC family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000373">
        <property type="protein sequence ID" value="OBZ85656.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NAK1"/>
    <dbReference type="FunCoup" id="A0A1C7NAK1">
        <property type="interactions" value="274"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NAK1"/>
    <dbReference type="InParanoid" id="A0A1C7NAK1"/>
    <dbReference type="OrthoDB" id="309640at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019239">
        <property type="term" value="F:deaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00448">
        <property type="entry name" value="YjgF_YER057c_UK114_family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1330.40:FF:000001">
        <property type="entry name" value="L-PSP family endoribonuclease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.40">
        <property type="entry name" value="RutC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006056">
        <property type="entry name" value="RidA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019897">
        <property type="entry name" value="RidA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035959">
        <property type="entry name" value="RutC-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006175">
        <property type="entry name" value="YjgF/YER057c/UK114"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00004">
        <property type="entry name" value="Rid family detoxifying hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11803">
        <property type="entry name" value="2-IMINOBUTANOATE/2-IMINOPROPANOATE DEAMINASE RIDA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11803:SF58">
        <property type="entry name" value="PROTEIN HMF1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01042">
        <property type="entry name" value="Ribonuc_L-PSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55298">
        <property type="entry name" value="YjgF-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01094">
        <property type="entry name" value="UPF0076"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ85656.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="127" mass="13719" checksum="E9571E2CFBB111D4" modified="2016-11-30" version="1">MSLSRVHTESAPAALGPYSQAIKVNGFVYTSGQIPIDPATGEVIEGGIKEHTKQVLVNLSEVLKAAGSSLEKVVKTTVFLRDMNDFVPMNEVYGSFFSTHQPARSCVQVARLPKDVPVEIECIALTD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NAM1</accession>
    <name>A0A1C7NAM1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="10">LETM1 and EF-hand domain-containing protein anon-60Da, mitochondrial</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">Letm1</name>
        <name evidence="10" type="ORF">A0J61_05789</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000323">
        <property type="protein sequence ID" value="OBZ86165.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NAM1"/>
    <dbReference type="STRING" id="101091.A0A1C7NAM1"/>
    <dbReference type="InParanoid" id="A0A1C7NAM1"/>
    <dbReference type="OrthoDB" id="73691at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043022">
        <property type="term" value="F:ribosome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030003">
        <property type="term" value="P:intracellular monoatomic cation homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033122">
        <property type="entry name" value="LETM1-like_RBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044202">
        <property type="entry name" value="LETM1/MDM38-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14009:SF6">
        <property type="entry name" value="LETM1 RBD DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14009">
        <property type="entry name" value="LEUCINE ZIPPER-EF-HAND CONTAINING TRANSMEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07766">
        <property type="entry name" value="LETM1_RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51758">
        <property type="entry name" value="LETM1_RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 7" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="3" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="117"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="domain" description="Letm1 RBD" evidence="9">
        <location>
            <begin position="148"/>
            <end position="318"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01094"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51758"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OBZ86165.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="318" mass="37206" checksum="F68E4D198A5DA271" modified="2016-11-30" version="1">MIRTTGRLTKGYPLLVLRGYQPLARASVQPWTKPMIQPIRTFSAPSGQNNQESQSRIMRFIQQSKELVRFYKDGLKQIWTDNKQSKALLTKVANEGYVLNRSEFQLVHQTQKNMVKLIPFGFVFLILPESIPLLVMYVPGMVPSTCLKESQIRKQREKLDKVRQKMTMNVLKSAEQVEGISPEDFLHRHKFQKIAKQYGYDFELSQIDRRHLSSYCRFMGINDYGPQFVLKHRLQKYMDYLDKDDKLLLQENTVDALDAKELSHAVEERGMRSLDREEEEMRRALKYWLTISQQSEPKVPAGLLVFSRMFLLNASYSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NAW1</accession>
    <name>A0A1C7NAW1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="3">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="primary">SMU1_3</name>
        <name evidence="17" type="ORF">A0J61_05713</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="3"/>
    <dbReference type="EMBL" id="LUGH01000317">
        <property type="protein sequence ID" value="OBZ86237.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NAW1"/>
    <dbReference type="STRING" id="101091.A0A1C7NAW1"/>
    <dbReference type="InParanoid" id="A0A1C7NAW1"/>
    <dbReference type="OrthoDB" id="248923at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106310">
        <property type="term" value="F:protein serine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01093">
        <property type="entry name" value="CRIB_PAK_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd06614">
        <property type="entry name" value="STKc_PAK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000768">
        <property type="entry name" value="Non-specific serine/threonine protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000705">
        <property type="entry name" value="Non-specific serine/threonine protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.810.10:FF:000005">
        <property type="entry name" value="Non-specific serine/threonine protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.810.10">
        <property type="entry name" value="CRIB domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000095">
        <property type="entry name" value="CRIB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036936">
        <property type="entry name" value="CRIB_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051931">
        <property type="entry name" value="PAK3-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033923">
        <property type="entry name" value="PAK_BD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45832">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE SAMKA-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45832:SF22">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE SAMKA-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00786">
        <property type="entry name" value="PBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00285">
        <property type="entry name" value="PBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101447">
        <property type="entry name" value="Formin homology 2 domain (FH2 domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50108">
        <property type="entry name" value="CRIB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 13" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8 17" id="KW-0418">Kinase</keyword>
    <keyword evidence="10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 13" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="CRIB" evidence="16">
        <location>
            <begin position="200"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="15">
        <location>
            <begin position="464"/>
            <end position="715"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="14"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="174"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="275"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="412"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="14">
        <location>
            <begin position="58"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="14">
        <location>
            <begin position="76"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="14">
        <location>
            <begin position="114"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="14">
        <location>
            <begin position="127"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="14">
        <location>
            <begin position="174"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="14">
        <location>
            <begin position="335"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="14">
        <location>
            <begin position="347"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="14">
        <location>
            <begin position="426"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="493"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="non-terminal residue" evidence="17">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008874"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="OBZ86237.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="740" mass="80761" checksum="3690435778E545F2" modified="2016-11-30" version="1" fragment="single">PAIGLVSANIKLFNSKADNQHDSPSPVKPTSVPPLPPKPIKKPITLSKTNDTNNIKQSSLLHHSPSLTSLHTAPLSPSPPSSPPPPPSSPPPPPPPPPPPPPPPPLPATPPRPINRNPNRSNYNNNTISKKNIPSHNTTHATLSPIVAQKSGSTLKGMLEKVVGSVSDLWTPANSLTSSPSNSALHKPQAANTNHGKAKISSPYNMVHVTHVGFNSQTGEFTGMPREWYVLLQQSGITKKEQQQNPQAVLDAIGFYKDANEHPLDSVWEKFDNVHPKSQLHSQPPTTATPPPLPQRARPQLVVVTQQDSPKPPVPSRPPQKKNSTPPAAPPIPARPEFVSNKANPKSSPPPKPPVSTKPKKPSTADDMAQALSSTPTPPPRTNKPPLVASNSNTTQDRLSSVFIASSAAPLDPALDMPSQQQLQQEKARQQRREQRQQKEALKDAQVIADLQAICTDADPTKLYRNMVKIGQGASGGVYTAQSVDTNMSVAIKQMNLAQQLKKEVIINEILVMREAHHKNIVNFIDSFLLMSNELWVVMEYMEGGSLTDVVTTSMMTESQIATVCRETLEGICYLHSLGIIHRDIKSDNVLLGLNGHVKLTDFGFCARLNDSEARTTLVGTPYWMAPEVVSRKEYGPKIDIWSLGIMVIEMIEGEPPYLHENPLRALYLIATNGTPALQHPDELSDQLKDFLQLSLTVDSAHRPDAKTLLDHAYLKKGDHTKSLIPLIKASRDLRKAHDM</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NBK4</accession>
    <name>A0A1C7NBK4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_07227</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000477">
        <property type="protein sequence ID" value="OBZ84724.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NBK4"/>
    <dbReference type="InParanoid" id="A0A1C7NBK4"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ84724.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="105" mass="12361" checksum="2C86925DAE9D99DE" modified="2016-11-30" version="1">MDSVAQLPNKPYLRFFVTTFGFLNNLLILYLYGFNSVNQYEMTYLVNCNKCILIILYCACQNTPEHFTKKLKVDRIYLEQDWLSDLNHINSDHSFTGNPLIDEQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NC67</accession>
    <name>A0A1C7NC67_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Myosin-2A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">MYO2A_0</name>
        <name evidence="13" type="ORF">A0J61_06999</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 8">Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000451">
        <property type="protein sequence ID" value="OBZ84954.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="FunCoup" id="A0A1C7NC67">
        <property type="interactions" value="96"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NC67"/>
    <dbReference type="InParanoid" id="A0A1C7NC67"/>
    <dbReference type="OrthoDB" id="6108017at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016459">
        <property type="term" value="C:myosin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051015">
        <property type="term" value="F:actin filament binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000146">
        <property type="term" value="F:microfilament motor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007015">
        <property type="term" value="P:actin filament organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd15480">
        <property type="entry name" value="fMyo2p_CBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd23767">
        <property type="entry name" value="IQCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01380">
        <property type="entry name" value="MYSc_Myo5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.820:FF:000001">
        <property type="entry name" value="Myosin heavy chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.190">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.530">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.20.240.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.850.10">
        <property type="entry name" value="Kinesin motor domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.720">
        <property type="entry name" value="Myosin VI head, motor domain, U50 subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002710">
        <property type="entry name" value="Dilute_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046943">
        <property type="entry name" value="Fungal_Myo2/2A_CBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000048">
        <property type="entry name" value="IQ_motif_EF-hand-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036961">
        <property type="entry name" value="Kinesin_motor_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001609">
        <property type="entry name" value="Myosin_head_motor_dom-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036103">
        <property type="entry name" value="MYSc_Myo5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13140:SF706">
        <property type="entry name" value="DILUTE CLASS UNCONVENTIONAL MYOSIN, ISOFORM C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13140">
        <property type="entry name" value="MYOSIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01843">
        <property type="entry name" value="DIL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00612">
        <property type="entry name" value="IQ"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00063">
        <property type="entry name" value="Myosin_head"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00193">
        <property type="entry name" value="MYOSINHEAVY"/>
    </dbReference>
    <dbReference type="SMART" id="SM01132">
        <property type="entry name" value="DIL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00015">
        <property type="entry name" value="IQ"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SMART" id="SM00242">
        <property type="entry name" value="MYSc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51126">
        <property type="entry name" value="DILUTE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50096">
        <property type="entry name" value="IQ"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51456">
        <property type="entry name" value="MYOSIN_MOTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8" id="KW-0009">Actin-binding</keyword>
    <keyword evidence="3 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 9" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6 8" id="KW-0505">Motor protein</keyword>
    <keyword evidence="5 8" id="KW-0518">Myosin</keyword>
    <keyword evidence="2 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Myosin motor" evidence="12">
        <location>
            <begin position="82"/>
            <end position="776"/>
        </location>
    </feature>
    <feature type="domain" description="Dilute" evidence="11">
        <location>
            <begin position="1277"/>
            <end position="1553"/>
        </location>
    </feature>
    <feature type="region of interest" description="Actin-binding" evidence="8">
        <location>
            <begin position="652"/>
            <end position="674"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1036"/>
            <end position="1067"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1084"/>
            <end position="1164"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="9">
        <location>
            <begin position="942"/>
            <end position="990"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="1048"/>
            <end position="1061"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="1084"/>
            <end position="1095"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="1132"/>
            <end position="1146"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="175"/>
            <end position="182"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008314"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51456"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="OBZ84954.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="1617" mass="185339" checksum="B3A6E9FC3C022D48" modified="2016-11-30" version="1">MSNSAHQAVEVYTQGTKAWFADDKEAWVSTTCVSNTVAGDSVRIVFQSDHDDQEYVFESTLTEVEKNGGSTLPPLRNPPKMEYTDDLTNLSYLNEPAVLNTIRTRYMQRLIYTYSGIVLIAVNPFDRVALYEPDIVQQYSGRRRGELEPHLFAISEDAYRCMIREQTNQTIVVSGESGAGKTVSAKYIMRYFATADDQESMSRKQKSSSGGMTEVEEQILATNPIMEAFGNAKTTRNDNSSRFGKYIQIEFDDAANIVGAKIRTYLLERSRLIYQPETERNYHIFYQLCAGIPLSEKKEFELGDYTQFHYLNQSGTGIIPGVDDASEFEITQRALSTVGLSVQIQWKIFRLLAALLHLGNIKITGRGDAMLSEDDPALLTATRLLGIKAADFRKWIVRKQIVTRSEKIVTNLSPAQAHVVKDSVAKYVYANLFDWLVAVTNESLSCSDANRVANFIGVLDIYGFEHFKKNSFEQFCINYANEKLQQQFNQHVFKLEQEEYVREKINWTFIEFSDNQKCIELIEAKLGILSLLDEESRLPSGSDQGFVQKLYTNFDNANFKNCFKKPRFSNSAFTIAHYALDVQYESESFIDKNKDTVPDEHLSLLQGSEFDFLVEVLDTAAASNPAPVAETNKRMSMIAKKPTLGSIFKLSLINLMDTIGSTNVHYIRCIKPNEAKIAWEFDPNMVLSQLRACGVLETIRISCAGYPSRWTFEEFADRYFALVSSKHWDPKNKPDVRELCSVILENSIKDEDKFQVGTTKIFFRAGQLAYLEKLRSDRFNECAVMLQKNMKRFIYRQRYVRTRELAIQIQCVARRKVAIAKTQTLREEKAAIAIQKYWRRYKARKEFIQKQAFILKLQTACRSCLAKRNHVAVRENNAAITIQRLVRGWFARKSYKAQRHFIIHIQSCIRRNIARKQLFHLRSEARSASHFKEVSYALENKVVELTQTLTAIREEKKSAQDRSVQLEAQIKTWMDKFEKMERRAKSLDERLQEPTVPQEQYDTLQNEFNTLTADHRATVDKAKSQEKEITLLRTQLETEKQETSSLRKQLEEAEERSKNATDESEVAELRSQLSALKVQLSQALNTPRRQQNNNGGLRALSPAPGLRNLSPSPNRAFDERQRSRSPHGGLYPTSTFSSEITPQPQQRKPRRNSAADMDNQRMKSSLDAIRSTENLGKNPRPTSIDHFGALMGAKTSGGLTGTADENPEDEIHALLRNEESLQEEILHGLIKSVKMPLPTLQNPPSQKEILFPSHTISICVNEMWHLGYLQESEQLLFAVMDTIQKQFLSFTDEDAVVPCTFWLTNVHELLSLICIAHVEFEQEVFQDKRKAVNRNDFNKLMDTIKFEMQCLEDNIYHAWMKEIKKHLSKMVIPAVVEGQSLPGFITSDNGRFFNKLLIGSSQPSYSMDDLLNFLNKVWRTMKCYYIEQSVATQALTELLKLIGVTAFNDLLMRKNFCSWKRAMQIQYNITRIEEWCKSHDIPEGALQLEHLMQTTKLLQFKKATLEDIENIYDVCWILSPTQIQKLISQYYTADYENPIKPEILKAVASHVVSGDKSDVLLLDSVSIDNTSNPFEVPIPRNTQPEIYLPSWLNLKRLRRLIGLIQQNNASSLKEPVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NC68</accession>
    <name>A0A1C7NC68_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Alkaline ceramidase 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">ACER3</name>
        <name evidence="10" type="ORF">A0J61_05782</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the alkaline ceramidase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000323">
        <property type="protein sequence ID" value="OBZ86166.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NC68"/>
    <dbReference type="STRING" id="101091.A0A1C7NC68"/>
    <dbReference type="InParanoid" id="A0A1C7NC68"/>
    <dbReference type="OrthoDB" id="187171at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016811">
        <property type="term" value="F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046513">
        <property type="term" value="P:ceramide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046514">
        <property type="term" value="P:ceramide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008901">
        <property type="entry name" value="ACER"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46187">
        <property type="entry name" value="ALKALINE CERAMIDASE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46187:SF3">
        <property type="entry name" value="ALKALINE CERAMIDASE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05875">
        <property type="entry name" value="Ceramidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0106">Calcium</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="8" id="KW-0862">Zinc</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="34"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="62"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="95"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="118"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="142"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="180"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="224"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="19"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="20"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="22"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="24"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="33"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="81"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="223"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="227"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009780"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR608901-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR608901-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OBZ86166.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="276" mass="32324" checksum="FF826E4C6B6C079D" modified="2016-11-30" version="1">MTTVHPDNYYWGQVTSTIDWCEENYAVSPYLAEFFNTTTNLGFLFTSMFGIYNIWRNGSNKALILAYLGVIFVGFGSWCFHMTLQYEMQLLDELPMIYVASIVMWLTFLADPSSPNNYKVPFALTLYSAIVTWSYLLINNPVFHQVCYAALILTIVYRSIVLHQQIPKDMTYERSRMQSMLWMSAFGFIIAFVLWNIDNVFCHHLRAWRHTVPLVIGALSELHGWWHIGTAIGCYYFIVFCEWIEPTLSKNDDAKYTLYWFGPLCYLRPNDNKKKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7ND95</accession>
    <name>A0A1C7ND95_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Ribonucleases P/MRP protein subunit POP1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">POP1</name>
        <name evidence="7" type="ORF">A0J61_04859</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000248">
        <property type="protein sequence ID" value="OBZ87083.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7ND95"/>
    <dbReference type="FunCoup" id="A0A1C7ND95">
        <property type="interactions" value="467"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7ND95"/>
    <dbReference type="InParanoid" id="A0A1C7ND95"/>
    <dbReference type="OrthoDB" id="442863at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005655">
        <property type="term" value="C:nucleolar ribonuclease P complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000172">
        <property type="term" value="C:ribonuclease MRP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001682">
        <property type="term" value="P:tRNA 5'-leader removal"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039182">
        <property type="entry name" value="Pop1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055079">
        <property type="entry name" value="POP1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009723">
        <property type="entry name" value="Pop1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012590">
        <property type="entry name" value="POPLD_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22731">
        <property type="entry name" value="RIBONUCLEASES P/MRP PROTEIN SUBUNIT POP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22731:SF3">
        <property type="entry name" value="RIBONUCLEASES P_MRP PROTEIN SUBUNIT POP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22770">
        <property type="entry name" value="POP1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06978">
        <property type="entry name" value="POP1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08170">
        <property type="entry name" value="POPLD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103025">
        <property type="entry name" value="Folate-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="Pop1 N-terminal" evidence="4">
        <location>
            <begin position="84"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="domain" description="POPLD" evidence="5">
        <location>
            <begin position="431"/>
            <end position="521"/>
        </location>
    </feature>
    <feature type="domain" description="POP1 C-terminal" evidence="6">
        <location>
            <begin position="631"/>
            <end position="723"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF06978"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF08170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF22770"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OBZ87083.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="724" mass="82281" checksum="56072C60229249D5" modified="2016-11-30" version="1" fragment="single">DIPKVTGPIDADRFALARIKEINDMQSAIKKSSYAMTELAFQSLPRGLRRRAASHNINRLPARLREKAAREAFKSAPGSKLIRKRVRKIKTPKNTVLEFLRRQKSKKWLETHMWHTKRMKMNDIWGYRIASRPNTKSVRVIYRSFTRLSVVHDASYMGCVELKGNSQQIITAINTITDITSASVGSERYIKGNRYGSTHLYEYLGFPTKLICPISFLWKPVTRDTLWLWIHPSAFHEAMTYIRLALEKTNASEVILNDLRNEILRFELTGPRSTALLQTILDPIEDDAVKGNQLWNDLEHLRTSASLSPGSVIGLVVNDPRLRFPQKVPLRTNEISLEDQRKVQQILENWPEDAANTSIWEEEGRKKLFDTRIAEYGLNLRRENNMIPGTKLEPTPEDSRIPLLLIQRGGPAFDTSNATKRALQSHEWAQGWSLIIPRGFGMAFWKSLVFAGGRVAGYDDMRAIQFESGFPSFPQDYPGTRAFEVHRAQVKNTLESVWQKRPAAKRVNYAKRGVEHPFECAFESLSNVEHMQVEPEHNLSVRPSYALVRGAQLAPSLLSDSRSFADILDLLKKKRGLNMEIHLPDPNDALVQARLKYIDRGKPAMNAMIYLIRDEATYRQCTSLIRCQAPSKSIKRKAKELLRATSASNKSIPIPSKREHIGYVTNGDFSLTLGYGFGIGACSISGLREIDALDSLNKRSAKRIVLIRNPSSLEVRPAQVEILF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NDG3</accession>
    <name>A0A1C7NDG3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Serine/threonine-protein kinase 19</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">STK19</name>
        <name evidence="2" type="ORF">A0J61_04930</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the STK19 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000253">
        <property type="protein sequence ID" value="OBZ87010.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NDG3"/>
    <dbReference type="STRING" id="101091.A0A1C7NDG3"/>
    <dbReference type="InParanoid" id="A0A1C7NDG3"/>
    <dbReference type="OrthoDB" id="10261701at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046579">
        <property type="term" value="P:positive regulation of Ras protein signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018865">
        <property type="entry name" value="STK19-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15243">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE 19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15243:SF0">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE 19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10494">
        <property type="entry name" value="Stk19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00093458"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ87010.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="284" mass="32959" checksum="18D8C73AE5E3144C" modified="2016-11-30" version="1">MNSSKRTKIATEQRLYQTQQGRIYKPDVYGIRRQKVRPPIHSDTTDDFDDIDHALIQVDSDSMTAAELLIQKNPQSNIPACLIHQIYSILPNHTTVDRELQEAFKSNLYRKFHVTGALEDEFLLMKTSDYDNNIIQARSEAMKDEHFDLSVFDRFKDHVQHLNEVTISKDKLIDTFGMNEKHIAQLVSFGLLLPHTHVDLYWFSVRGQGTFMSKLNAGRAEIIRMLRKRHTHNIMEKLLLQKKMRKTNFSMEFLLYDLVGSGRVERHSTPMGDLIQLTTKGGKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NDQ8</accession>
    <name>A0A1C7NDQ8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_05044</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000262">
        <property type="protein sequence ID" value="OBZ86909.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NDQ8"/>
    <dbReference type="STRING" id="101091.A0A1C7NDQ8"/>
    <dbReference type="InParanoid" id="A0A1C7NDQ8"/>
    <dbReference type="OrthoDB" id="63267at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd11651">
        <property type="entry name" value="YPK1_N_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ86909.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="136" mass="15533" checksum="E8983AB54866A0C7" modified="2016-11-30" version="1">MNSWKLPGVRNKNKETTTTTTTERPSAVVKNEPQSGVLLIRICDARGITPPSDITLPADQQVAIQRQSNRDSLSRKQHWWLPYVVLEFDKNEVLIDSLGGTTQNPVYQYRAHFDVSRSSEVSISMYMRHPPPKQVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NDU2</accession>
    <name>A0A1C7NDU2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Putative metal ion transporter C17A12.14</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">A0J61_04711</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000236">
        <property type="protein sequence ID" value="OBZ87238.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NDU2"/>
    <dbReference type="STRING" id="101091.A0A1C7NDU2"/>
    <dbReference type="InParanoid" id="A0A1C7NDU2"/>
    <dbReference type="OrthoDB" id="29879at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015095">
        <property type="term" value="F:magnesium ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010961">
        <property type="term" value="P:intracellular magnesium ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd12829">
        <property type="entry name" value="Alr1p-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.460.20">
        <property type="entry name" value="CorA soluble domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.340">
        <property type="entry name" value="Magnesium transport protein CorA, transmembrane region"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044089">
        <property type="entry name" value="Alr1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045861">
        <property type="entry name" value="CorA_cytoplasmic_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045863">
        <property type="entry name" value="CorA_TM1_TM2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002523">
        <property type="entry name" value="MgTranspt_CorA/ZnTranspt_ZntB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21535">
        <property type="entry name" value="MAGNESIUM AND COBALT TRANSPORT PROTEIN/MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21535:SF51">
        <property type="entry name" value="MANGANESE RESISTANCE PROTEIN MNR2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01544">
        <property type="entry name" value="CorA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143865">
        <property type="entry name" value="CorA soluble domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144083">
        <property type="entry name" value="Magnesium transport protein CorA, transmembrane region"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="475"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="506"/>
            <end position="527"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="61"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="64"/>
            <end position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009765"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OBZ87238.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="533" mass="61846" checksum="06AF7D4F1DAC42C4" modified="2016-11-30" version="1">MSSNPYFTSNYNPSQSKVIDRSTRLVGTQHANLLQTEPKDLDKLFHRNSFQQKAEEDICFPSNKRPSVSSNTSTLNGHQRPSRQPADAISSIIQTAKEVNLNALQDLFDESKSAYDGSRVAMSYQDSKFPYKKDLDDYISNQRIENKLLSLYGDNNLTHNHGQQQQQNRYSEHSYLQRIESKNRFMYYHPDTGSLVGETLQGINLPPDTTLEELLLRDNYWLDVTLPNENEMAAISKMFHIHPLTTEDIMSFEIREKCDVFRDYMFVCYRAFIHDYQQLRPVTFYNIITKKHILTFHFDHVPHVHHVKQRIRQLQDYIEIVPDWINYAIMDEITDSFAPIIQQIESEVDSIDDSVMLYKANQTDVVLRIGTCRKKVIQMVRLLGTKVEVIRGLTKRILEEHQADQDMLDTLLTEEKIYPDVGLYLGDVQDHILTMLQNLSHYETVLARSESNYLARISIELTQTSNSTNHVIGRLTIFATIMLPMNLITGLWGMNVKVPGKDYDNLTYFFWIISSLVIFAILSLTLAKRIKLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NE96</accession>
    <name>A0A1C7NE96_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Methionine synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">MTR_0</name>
        <name evidence="13" type="ORF">A0J61_05093</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the vitamin-B12 dependent methionine synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000265">
        <property type="protein sequence ID" value="OBZ86866.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NE96"/>
    <dbReference type="STRING" id="101091.A0A1C7NE96"/>
    <dbReference type="InParanoid" id="A0A1C7NE96"/>
    <dbReference type="OrthoDB" id="261426at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031419">
        <property type="term" value="F:cobalamin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008705">
        <property type="term" value="F:methionine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050667">
        <property type="term" value="P:homocysteine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046653">
        <property type="term" value="P:tetrahydrofolate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02069">
        <property type="entry name" value="methionine_synthase_B12_BD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1240.10:FF:000001">
        <property type="entry name" value="Methionine synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.280:FF:000001">
        <property type="entry name" value="Methionine synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.280">
        <property type="entry name" value="Cobalamin-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.288.10">
        <property type="entry name" value="Cobalamin-dependent Methionine Synthase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.20">
        <property type="entry name" value="Dihydropteroate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1240.10">
        <property type="entry name" value="Methionine synthase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.196.10">
        <property type="entry name" value="Vitamin B12-dependent methionine synthase, activation domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003759">
        <property type="entry name" value="Cbl-bd_cap"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006158">
        <property type="entry name" value="Cobalamin-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036724">
        <property type="entry name" value="Cobalamin-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011005">
        <property type="entry name" value="Dihydropteroate_synth-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050554">
        <property type="entry name" value="Met_Synthase/Corrinoid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033706">
        <property type="entry name" value="Met_synthase_B12-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036594">
        <property type="entry name" value="Meth_synthase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000489">
        <property type="entry name" value="Pterin-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004223">
        <property type="entry name" value="VitB12-dep_Met_synth_activ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037010">
        <property type="entry name" value="VitB12-dep_Met_synth_activ_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45833">
        <property type="entry name" value="METHIONINE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45833:SF1">
        <property type="entry name" value="METHIONINE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02310">
        <property type="entry name" value="B12-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02607">
        <property type="entry name" value="B12-binding_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02965">
        <property type="entry name" value="Met_synt_B12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00809">
        <property type="entry name" value="Pterin_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01018">
        <property type="entry name" value="B12-binding_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52242">
        <property type="entry name" value="Cobalamin (vitamin B12)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51717">
        <property type="entry name" value="Dihydropteroate synthetase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56507">
        <property type="entry name" value="Methionine synthase activation domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47644">
        <property type="entry name" value="Methionine synthase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50974">
        <property type="entry name" value="ADOMET_ACTIVATION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51332">
        <property type="entry name" value="B12_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51337">
        <property type="entry name" value="B12_BINDING_NTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0846">Cobalamin</keyword>
    <keyword evidence="8" id="KW-0170">Cobalt</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2 9" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="4 9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="B12-binding N-terminal" evidence="12">
        <location>
            <begin position="116"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="domain" description="B12-binding" evidence="11">
        <location>
            <begin position="224"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="domain" description="AdoMet activation" evidence="10">
        <location>
            <begin position="375"/>
            <end position="712"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010398"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022628"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51332"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51337"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="OBZ86866.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="712" mass="79867" checksum="27810155A42AB997" modified="2016-11-30" version="1">MEEHNNYAVEFIEACRGIKSTLPGAKISGGVSNLSFAFRGMDKVREAMHSVFLYHTVKCGMDMGIVNAGFLTVYDDIPKDLLTLCENAVWNCDPEVTEKLLEYAKAHSKDAKKDEDQEEWRNWSVTERITHALVKGIMKHIVEDTEEARLDKEKYPRSLNVIEGPLMAGMNVVGDLFGKGKMFLPQVIRSARVMKKAVAHLVEFIKIEKEQDMALSGETEMKGNGTIVMATVKGDVHDIGKNICGVVLGCNNYKVIDLGVMVPCDVIIKTAIEQKADVIGLSGLITPSLEEMVIVAKECQKAGLTIPILIGGATTSKMHTAVKIAPQYASPTIYVLDASRSVPVVASLLDDNLREDFAQDIREEYDEMREEYYEGLEERCLLSIEAARERKMQIDWLKHPPAIKPKFLGTKVYNNYPLKKLVDHIDWNPFFQVFQLRGRYPNRGFPKIFDDEHVGVEAKRLYNDAQDMLNTIISQNRLEARGLVGFYPAHAVGDDIEVYSDESCTETIATFYGLRQQAEKDTDEPYYCLSDFVSPKASQIPDYIGMFAVSTGFGCDELVKQYEEDGDDYNSIMAKAIADRLAEAFAEALHEQVRKEDWGYASEEHLSAADLFAVRYQGIRPAPGYPSQPDHTEKETMWRLGSIAEKTGITLTESLAMDPPASVSGLLFGHSQSKYFAVGKIEKDQIKDYAARKNMQVETVEKWLGTILAYDH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NEB6</accession>
    <name>A0A1C7NEB6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Autophagy-related protein 18</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">ATG18</name>
        <name evidence="5" type="ORF">A0J61_04653</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the WD repeat PROPPIN family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000232">
        <property type="protein sequence ID" value="OBZ87290.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NEB6"/>
    <dbReference type="FunCoup" id="A0A1C7NEB6">
        <property type="interactions" value="346"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NEB6"/>
    <dbReference type="InParanoid" id="A0A1C7NEB6"/>
    <dbReference type="OrthoDB" id="1667587at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048720">
        <property type="entry name" value="PROPPIN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11227">
        <property type="entry name" value="WD-REPEAT PROTEIN INTERACTING WITH PHOSPHOINOSIDES WIPI -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21032">
        <property type="entry name" value="PROPPIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="1" id="KW-0853">WD repeat</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="7"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00025740"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OBZ87290.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="353" mass="38457" checksum="CB0A6D1D853BDB76" modified="2016-11-30" version="1">MLLQNNFILAAGGTGIVEMLFCTSLVALVGAGEHPAFSPRQLQIINTKRQTTICELSFPTAILAVKMNRRRLIVVLEELIYLYDISNMKLLHTIETNPNPQAICALSPSSENCFIAYPARSSSSPFSPNSNNSSYLSGDVELFDALGPQTTNIVQAHKSPISCISMNSEGTLLATASEKGTVIRIFSTLDATKVYQFRRGSYAAKIYSMSFNLVSSLLCVSSDTDTVHIFKLSSNGSPVDKDKEARGRSASVGQMLRRSSMHLGRNLAGSVGSYLPEVLTEMWEPTRDFASLKLPSGGVRSLVALSSTTPQVMVVTSEGYFYQYNIDLESGGECVLLKQFSLLEPSDDNVMDQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-06-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NEB8</accession>
    <name>A0A1C7NEB8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_04507</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000222">
        <property type="protein sequence ID" value="OBZ87437.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NEB8"/>
    <dbReference type="InParanoid" id="A0A1C7NEB8"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ87437.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="196" mass="22455" checksum="DA825F8D0C7308CD" modified="2016-11-30" version="1">MKMSKGQQYYLKAFQLNAESLYCLRCSTQKEQVDIHTQYYSSARLKTGKVGNYERNKLKEATGSLSKEAFRQQPNRTNMVLLQLKPKPTEAGLCSCLANIMTIIRNIVNRIRSTQSGQQEQLIRCRFVTISTLVKGDQRTEKVLRYIQRAYVNKWGVIFKSEDAHLDQDFIFSGIVKVLDSVPVPLKKISLSLEAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NEK6</accession>
    <name>A0A1C7NEK6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">FAS1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">A0J61_04765</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000240">
        <property type="protein sequence ID" value="OBZ87189.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NEK6"/>
    <dbReference type="STRING" id="101091.A0A1C7NEK6"/>
    <dbReference type="InParanoid" id="A0A1C7NEK6"/>
    <dbReference type="OrthoDB" id="286301at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.180.10">
        <property type="entry name" value="FAS1 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050904">
        <property type="entry name" value="Adhesion/Biosynth-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036378">
        <property type="entry name" value="FAS1_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000782">
        <property type="entry name" value="FAS1_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10900:SF77">
        <property type="entry name" value="FI19380P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10900">
        <property type="entry name" value="PERIOSTIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02469">
        <property type="entry name" value="Fasciclin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00554">
        <property type="entry name" value="FAS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82153">
        <property type="entry name" value="FAS1 domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50213">
        <property type="entry name" value="FAS1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008889658" description="FAS1 domain-containing protein" evidence="2">
        <location>
            <begin position="21"/>
            <end position="547"/>
        </location>
    </feature>
    <feature type="domain" description="FAS1" evidence="3">
        <location>
            <begin position="29"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="domain" description="FAS1" evidence="3">
        <location>
            <begin position="330"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="262"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="489"/>
            <end position="518"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="489"/>
            <end position="506"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50213"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OBZ87189.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="547" mass="57845" checksum="E0ADDEB03DFAE182" modified="2016-11-30" version="1">MHWKYVIEVSLLIFLTTIFAQQVQQQNGNQTILQILNNTDSSPAFDFVQFLQSSPDYQPILDLLSGSASSNITMFVPSNQAFNAMNNTDRGSSDSSEFSQNGSIGMYFSSLLSGRVSSTLTSMQASTTTAGSQVQASSPVTTTTDGQAVSEISSFLGSLLPQATNAVNILPNLAKHIRRADTEMQNDTSSTSLINQYNMIDVLYYHVINQSISLSNNTMVFNTLLTNSTVDKLGYGLPLLVQQSQQQSQQVQDQAKWLYKRQQASNGTSDNGASNNGTIGDGQINDTTSSIWTVGTGTENDASFATNQSIQGSNGIAYIIDKILVPPANPNQTLNKLANASLFDSILGQLSDDSLDTSSNVTLFVPVNQALQNISNTSLDAQTSSQIVLAHVVPGIYYSTNLTSQPTTVTSLAGTNISMTNANDPSDNNMQVNGFNVVHPNVLLNNGVMHLIDGVLVYLSSQTVGNNTSGNSTGVAGSTSSVISTSTGMSASSTSAAGVTTSGTSGPDSTNNSLPPPTGSLASKQYNAFDSFAITLTALILLFYTVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NFG1</accession>
    <name>A0A1C7NFG1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">A0J61_04116</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000194">
        <property type="protein sequence ID" value="OBZ87835.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NFG1"/>
    <dbReference type="InParanoid" id="A0A1C7NFG1"/>
    <dbReference type="OrthoDB" id="2369992at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050815">
        <property type="entry name" value="TF_fung"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47338:SF5">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47338">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="53"/>
            <end position="90"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OBZ87835.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="531" mass="61985" checksum="A820C41DF157993E" modified="2016-11-30" version="1">MRMVRNKPCAYCQKRRRRCVRPDPKAPCELCNQKQKTCIQGHLSNNSSSDSEEEQARMKIEQEKELLDQVQTLEDELEQMEIAIRQHRKQMLGQREWHMLLQNGSLQLESNIDSLEDLFHFGNAAIRYLSPFGKFFENTLRKTPEERVPSYIRAKVITLGKGQLEVLKTELNEENDEDTYCLIRSVNPRYIVSKLVDMYFSCLETTLFVLHEPSFRAHFNSLEDPLDDVITLAICTVAPLSGCQHNCFTNQEKRRTSEYFYQLCKEKVLGIYQDPKHILESLIAINCMQLFHLCTLRFDEICKWKDTSLIIIEFAYPEIIGYQPRNTSNLSELERIRKGVLFRNIYLINYTCFFFEFFFQYKSVKLLKYDLYFDCLPGESEKLQYHTETLNHVMELLFDDATAEVTSCVYRLAAGDTGGVQFELVLRIEQSVDKWWSKLPDRLKLCDHVFDLTKEVIENTVDVPKLKIAYYMAEHILVVYTYAMQTISVDKTDSASVAIKDKLISRIAKMTDVFVSATSKINSMDTECNCK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NFJ1</accession>
    <name>A0A1C7NFJ1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 6">Altered inheritance of mitochondria protein 24, mitochondrial</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">aim24</name>
        <name evidence="8" type="ORF">A0J61_04068</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the AIM24 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000191">
        <property type="protein sequence ID" value="OBZ87881.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NFJ1"/>
    <dbReference type="STRING" id="101091.A0A1C7NFJ1"/>
    <dbReference type="InParanoid" id="A0A1C7NFJ1"/>
    <dbReference type="OrthoDB" id="1705416at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007007">
        <property type="term" value="P:inner mitochondrial membrane organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.160.10">
        <property type="entry name" value="Mitochondrial biogenesis AIM24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002838">
        <property type="entry name" value="AIM24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036983">
        <property type="entry name" value="AIM24_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016031">
        <property type="entry name" value="Trp_RNA-bd_attenuator-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36959">
        <property type="entry name" value="ALTERED INHERITANCE OF MITOCHONDRIA PROTEIN 24, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36959:SF2">
        <property type="entry name" value="ALTERED INHERITANCE OF MITOCHONDRIA PROTEIN 24, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01987">
        <property type="entry name" value="AIM24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51219">
        <property type="entry name" value="TRAP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0809">Transit peptide</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="334"/>
            <end position="373"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009322"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013287"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU363045"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OBZ87881.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="389" mass="43044" checksum="CDCB44E073514DC4" modified="2016-11-30" version="1">MYRRVLTNLRPSQRTYVGLAFNQQSKQETAETVDRSLKSFQHTVNGPSNTISEVGKDIGMENEKEPIFEVLSSGVGSALLVKLPPDAEITAATGSSLGASTKVLSKLSLDKSTVRSIGRKLVGDSMFYQKYYTKNTAGDILLAPQRIGEIATIQLKNSAKYILRRDAFLAKTEKVTFDLGVHHQESGLVNKLIHTVTGPGTLAISHYGGLYRISLAAGEEYQANPRNLVMWDKRLNPTRLHSVKPVVPSPRSKLRQYEVFRNIVDSPSLQPKLQYLDSLSRTLRNIILGAPDFVKLKGPGDFYLASRVESRFEKSRLMNALAAANDSASQLFEQSNDIFPPGPPEPLQDYSSSKKKHPGYAQKSVDGRPSYYAQVGPRGQITFIANKNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NFM1</accession>
    <name>A0A1C7NFM1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_04023</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000188">
        <property type="protein sequence ID" value="OBZ87921.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NFM1"/>
    <dbReference type="STRING" id="101091.A0A1C7NFM1"/>
    <dbReference type="InParanoid" id="A0A1C7NFM1"/>
    <dbReference type="OrthoDB" id="8693905at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="47"/>
            <end position="91"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ87921.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="91" mass="10416" checksum="170D425B704481EE" modified="2016-11-30" version="1">MPIIQLRPEDAEHIRSYARALGLTPQEEKALNDNQALISHTLALQQQSKLDPGTLRQKAQQKQMHSHREEKRKLRHLPGRKGTSSEECIIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NFN3</accession>
    <name>A0A1C7NFN3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">60S ribosomal protein L33-A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">RPL33A_1</name>
        <name evidence="4" type="ORF">A0J61_04056</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the eukaryotic ribosomal protein eL33 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000190">
        <property type="protein sequence ID" value="OBZ87897.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NFN3"/>
    <dbReference type="FunCoup" id="A0A1C7NFN3">
        <property type="interactions" value="385"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NFN3"/>
    <dbReference type="InParanoid" id="A0A1C7NFN3"/>
    <dbReference type="OrthoDB" id="1166329at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.10.190:FF:000001">
        <property type="entry name" value="60S ribosomal protein L35a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.190">
        <property type="entry name" value="translation elongation factor selb, chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00573">
        <property type="entry name" value="Ribosomal_eL33"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001780">
        <property type="entry name" value="Ribosomal_eL33"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038661">
        <property type="entry name" value="Ribosomal_eL33_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10902">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L35A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01247">
        <property type="entry name" value="Ribosomal_L35Ae"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="Translation proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009269"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OBZ87897.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="105" mass="11930" checksum="29667E5D0682FFCB" modified="2016-11-30" version="1">MSDRLYSKGRVLGFERAKRTQNPNTSLIQIEGVQTTSDAKFYLGKRVAYVYRAQREINGSKIRVIWGRIARTHGTSGVVKARFRKNLPPKVFGASVRVMLYPSNI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NFZ8</accession>
    <name>A0A1C7NFZ8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Nucleoporin Nup133/Nup155-like N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">A0J61_03894</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000178">
        <property type="protein sequence ID" value="OBZ88053.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NFZ8"/>
    <dbReference type="STRING" id="101091.A0A1C7NFZ8"/>
    <dbReference type="InParanoid" id="A0A1C7NFZ8"/>
    <dbReference type="OrthoDB" id="338970at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044611">
        <property type="term" value="C:nuclear pore inner ring"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017056">
        <property type="term" value="F:structural constituent of nuclear pore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006606">
        <property type="term" value="P:protein import into nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036228">
        <property type="term" value="P:protein localization to nuclear inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006405">
        <property type="term" value="P:RNA export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000972">
        <property type="term" value="P:transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.1780">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1880">
        <property type="entry name" value="Nucleoporin, helical C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014908">
        <property type="entry name" value="Nucleoporin_Nup133/Nup155_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004870">
        <property type="entry name" value="Nucleoporin_Nup155"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042538">
        <property type="entry name" value="Nucleoporin_Nup155_C_3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10350">
        <property type="entry name" value="NUCLEAR PORE COMPLEX PROTEIN NUP155"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10350:SF6">
        <property type="entry name" value="NUCLEAR PORE COMPLEX PROTEIN NUP155"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08801">
        <property type="entry name" value="Nucleoporin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Nucleoporin Nup133/Nup155-like N-terminal" evidence="4">
        <location>
            <begin position="50"/>
            <end position="378"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF08801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OBZ88053.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="981" mass="112487" checksum="DD6ADE1DD5A5FC61" modified="2016-11-30" version="1">MTNRLQLVVNPSLKAVQQNVNSLIQNDQVPFDLDDYLKMSDYSIQHEKAFSQSALKPYPKVWSTKIQENAYKIGFLQTIGRVWLSTNNILYLWDYQTNDCFRYECDNVIQHVDLIDFDQQFELIVSTADFLFSHTIKREDDKLKIASSTMVKTNGVVMNNMVATKDTKRLFMIGSNGHLYELFLTFDQAISTDARLACHTENPFMCYLPSFFRSAPVTKVKSIAIKNDVLYVLEDNSTIHAVNVNGSLYASMQRYSGSCLASIHTIPDTESSKLQLMAVSEKGDRFYFSYQHPDFLLIHTRPAPPLPGSYLFNQLSQEQVKTVFYQQGVFGAVLCKAEKQFLIWTCADAVETDQKKLVENTYMEPLIYPIWDLSQLNQTESISPYKRTRHCIEQSRIEYMALSEAGLIQYTQHSPVDYLQQILQSDDSVSKLLDFSQCYSHLETICMAYVLACSPERKMTEAVNYLSQSVRKDEGFLLYFSRIVHNIWTGDIVHESTPLLPWTVAQERLKELWTTVQSTHITIKDDLLNLTERTIESISLINFIYQLQWDQIKKTLKSNSVDVSITFADLVSTEHGAQLCQEIVLTAIQQSKLANVTNQFSFIGGFLESNCQSLFGKDKVIYYKGLECLESAGHYPEQADEAIEKALAHLQTVIEMLDITTINELSKRMMVLDHHLSSVQLILAKYQTVDTTSHEALFAILLPVVEAIVQQGESKARPILMNALKLTSDPEFHHQIYCWLYDHKQRQLMITLETPLLLNYIQTHILNLPERYASLKKFYTYRQQHELAIDSLFTLATEVDQVALPNRIRLLQTACHELPLMPYNEHTKQKAEHIQYTSKVAQIQLDMHTSLAERSNEVEVETLASITSSLLPDNELLAIAYQYSLYESALYLLHLLERFDWEFVKRAWSGIVSSYQDETLLKAKVTELANRLYPSISSFPVYIILQNLQEHLTPDFAFNTLVEAGVPSEVVSDAKEAISSY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NG95</accession>
    <name>A0A1C7NG95_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Protein transport protein SFT2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">SFT2</name>
        <name evidence="9" type="ORF">A0J61_03952</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Nonessential protein required for the fusion of transport vesicles derived from the endocytic pathway with the Golgi complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Golgi apparatus membrane</location>
            <topology evidence="8">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7 8">Belongs to the SFT2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000182">
        <property type="protein sequence ID" value="OBZ88000.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NG95"/>
    <dbReference type="FunCoup" id="A0A1C7NG95">
        <property type="interactions" value="229"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NG95"/>
    <dbReference type="InParanoid" id="A0A1C7NG95"/>
    <dbReference type="OrthoDB" id="660759at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000138">
        <property type="term" value="C:Golgi trans cisterna"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042147">
        <property type="term" value="P:retrograde transport, endosome to Golgi"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007305">
        <property type="entry name" value="Vesicle_transpt_Got1/SFT2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011691">
        <property type="entry name" value="Vesicle_transpt_SFT2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23137:SF36">
        <property type="entry name" value="VESICLE TRANSPORT PROTEIN SFT2C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23137">
        <property type="entry name" value="VESICLE TRANSPORT PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04178">
        <property type="entry name" value="Got1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 8" id="KW-0653">Protein transport</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2 8" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="81"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="109"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="143"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="167"/>
            <end position="188"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00025800"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU363111"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OBZ88000.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="212" mass="23113" checksum="2B2DF76D3BB0D396" modified="2016-11-30" version="1">MSQTESSFKSSLRNFQLSRSNNIALPTNTGQNSGGLSSFRDSASNLFSNMTSTVQGYVPLGNNIEEEDEDPWYQLSRVERVMAFALCLALGIGCFALSFFFLPLFPGKFAATFTLGSILILVSVALLRGPWSHLKHMMSRERLPFTVSYVGSMALTLYAAIGIRAVILTVLFAVIQIIALLWYVGSYIPGGVSTLRYATSYIGGRAASILPI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NHF5</accession>
    <name>A0A1C7NHF5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Putative transporter C3B8.04c</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">A0J61_03530</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000153">
        <property type="protein sequence ID" value="OBZ88430.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NHF5"/>
    <dbReference type="FunCoup" id="A0A1C7NHF5">
        <property type="interactions" value="177"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NHF5"/>
    <dbReference type="InParanoid" id="A0A1C7NHF5"/>
    <dbReference type="OrthoDB" id="10260443at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005315">
        <property type="term" value="F:phosphate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006817">
        <property type="term" value="P:phosphate ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006797">
        <property type="term" value="P:polyphosphate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01115">
        <property type="entry name" value="SLC13_permease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd14478">
        <property type="entry name" value="SPX_PHO87_PHO90_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004680">
        <property type="entry name" value="Cit_transptr-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004331">
        <property type="entry name" value="SPX_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10283:SF92">
        <property type="entry name" value="LOW-AFFINITY PHOSPHATE TRANSPORTER PHO91"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10283">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 13 MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03600">
        <property type="entry name" value="CitMHS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03105">
        <property type="entry name" value="SPX"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51382">
        <property type="entry name" value="SPX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="329"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="360"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="413"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="459"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="499"/>
            <end position="521"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="542"/>
            <end position="563"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="583"/>
            <end position="604"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="611"/>
            <end position="628"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="640"/>
            <end position="658"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="679"/>
            <end position="712"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="724"/>
            <end position="746"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="767"/>
            <end position="793"/>
        </location>
    </feature>
    <feature type="domain" description="SPX" evidence="8">
        <location>
            <begin position="1"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="112"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OBZ88430.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="795" mass="88546" checksum="718F9D11FC7AF758" modified="2016-11-30" version="1">MKFSHQIQFNSVPDWADYYLPYSNLKKLIYSIEKERITGQRERSSIDLEDGREASERTALISENPIELENQQFIDALNKSLDKIVKFYAKKETELYDEMNMLLEDFEQLETQGTPSHSRRLSHQEAGRIRSNTNQLPRRESNVEGDSFLPPNIISKNVIENDPAVAESTYVQHSWPKDMAYDVVELKRRIVDLFVLLSELKSFVALNLTAFAKILKKYDKITNNNLKKYYTATYVSQAYPFETNTKARLNERIQQSERAYAFLATDNDLDQAIEELKAHLREHIVWERNTVWRDMIGQERRTQTVGLSDVKPSPIHTPFGMLNVARDQVMNYLYMAASVAIFILLLRAELFDTVEQNRCLAILVFASMLWAGEVMPLFVTALLVPLLIITLRVMRSDDGHFTRLSAPDATKRVFGAMFSPVIMLLLGGFAIAGALSKFGIAKSMATFVLSKAGTRPNSVLIVNMMVATVASMWISNVAAPVLCFSLIQPILRTLPVDSTFGPCLIIGIALASNLGGMASPISSPQNIIAIQNMNPAPSWAEWFIISIPLCIIGNLIIWLWLLYNYNPEKKTPQIHTIRANSDPITGTQVYVVLVTLLTIVLWCLAHSYEHIFGDMGVIAILPLIAFFGTGLLTKDDFNNFLWNVIMLAMGGIALGKAVESSGLLKTIASQIETLVQGFSAFEVLFVFSCLVLVIATFISHTVAALIVLPIVAEVGSQLADPQPRMLVMGTAFVCSAAMGLPVSGFPNMNAISQENELGKPYLSTKDFLINGVPSSIFAMLCITTIGYGLMALIGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NHK9</accession>
    <name>A0A1C7NHK9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Virulence protein SSD1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">SSD1_0</name>
        <name evidence="4" type="ORF">A0J61_03336</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the RNR ribonuclease family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000141">
        <property type="protein sequence ID" value="OBZ88622.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NHK9"/>
    <dbReference type="FunCoup" id="A0A1C7NHK9">
        <property type="interactions" value="44"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NHK9"/>
    <dbReference type="InParanoid" id="A0A1C7NHK9"/>
    <dbReference type="OrthoDB" id="372421at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000932">
        <property type="term" value="C:P-body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000175">
        <property type="term" value="F:3'-5'-RNA exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006402">
        <property type="term" value="P:mRNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.700:FF:000002">
        <property type="entry name" value="Cell wall biogenesis protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.690">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.700">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041505">
        <property type="entry name" value="Dis3_CSD2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041093">
        <property type="entry name" value="Dis3l2-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001900">
        <property type="entry name" value="RNase_II/R"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050180">
        <property type="entry name" value="RNR_Ribonuclease"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23355:SF9">
        <property type="entry name" value="DIS3-LIKE EXONUCLEASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23355">
        <property type="entry name" value="RIBONUCLEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17877">
        <property type="entry name" value="Dis3l2_C_term"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17849">
        <property type="entry name" value="OB_Dis3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00773">
        <property type="entry name" value="RNB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00955">
        <property type="entry name" value="RNB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RNB" evidence="3">
        <location>
            <begin position="543"/>
            <end position="876"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="41"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="199"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="41"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="78"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="201"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="229"/>
            <end position="243"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005785"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00955"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OBZ88622.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="1125" mass="126493" checksum="3771CBCD6E573F4A" modified="2016-11-30" version="1">MNHETLEQQTAPESTRGLFDGPEMVTPTRSFSDKRRTFHGLSSHQFDNNGRNRQPVSLMPTPRHHRSRSTVNSEIVVSPSKSTNSLSSSGHYNNNGNKNRRSFVGLHTLKEEMTVDSLQDMINTLKTLPPIISPVPPVDDNSFVSREAALAEAEAKLMGTFNRRDDTNAKKRVSHQQLPVLNENGESFLSDHVNKRTSMNSKSLSLSLGGSENRKSAHRSSRNFDEWRNSTSSNSGSTSNRSSFNLVPFTPTRVNFSRDDANPHQRRPLFIAHLPFSALTPLFRARQLVRGILRVNKRNRSDAYVTCDELDGCDIYICGSRDRNRALEGDVVAVRLVNVEKVIREKQEKEDAKLARNNGQRKVRLPDEEDENEIIFGGDDEIDVVKPKYAGVVVAILERAQNQVFSGTLTLMRPNNKRAALQQQEEEETGTKKETPRIVWFKATDKRVPLIAIPIEQVPHDFVEKNEEYKNRLFVGSIKRWPITSLHPFGTLEKELGAITDLEVQIKAILADSNVTHTPFTEAVMECVPPSPFQFTPPEDGSRRDLTLDPEHRMITIDPTGSTILEDGLSIVRLGDDTYEVGVHVADVAYFIKPHSPLDKEARARAVSVCLDQKTVPIIPSELSDVANFTVNQSKPAFSVIWKLSSDGMLLDTWFGKTVVKSSAQLTYDDAQEIVQGNDDSRYSQEINNDVRMLYNLACTLYSTRYTKDAMALVKQTLVFDDPNQPTQVTIAEARPDILKIVKEFAFLANKCVAQKISSQYPEQALLRRQAPPDSRKIHELKDYASRFLGVELNITDAISIQKSIQEIKDEELRQLVSILVLKTMQPPKYFCAGTFDISKYFHFSSGVPLFTHFTSPLRRYADIIVHRQLEATLNGEKHFFLDRDTVQKLAQHCNVKKEASLSAREQGKLLSLALYLVHTQDGSQPHQAVTTNTPLTTTVYSEARVIAVTEEYFDVSLPEFGMERRIHLANLPMYKPQFDPFERALTMFWKKGVVPSTGEQQPWSLSDDEYEEEELLSSFPESSQSTPLVKTTTNSLENDKQFEAIALAASRAGIVPSSTTSTPGKKSASKRASIISSRLSTSTGYSSEQSSQTIKALDRIRVMLTIEMVRTPPLIRVFAANPYA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NIP1</accession>
    <name>A0A1C7NIP1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Nucleolar protein 4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">Nol4_2</name>
        <name evidence="2" type="ORF">A0J61_02944</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000119">
        <property type="protein sequence ID" value="OBZ88997.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NIP1"/>
    <dbReference type="STRING" id="101091.A0A1C7NIP1"/>
    <dbReference type="InParanoid" id="A0A1C7NIP1"/>
    <dbReference type="OrthoDB" id="2499658at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.340.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041588">
        <property type="entry name" value="Integrase_H2C2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17921">
        <property type="entry name" value="Integrase_H2C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Integrase zinc-binding" evidence="1">
        <location>
            <begin position="114"/>
            <end position="162"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF17921"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ88997.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="340" mass="37584" checksum="B782D6D5751E0A15" modified="2016-11-30" version="1">MRAEQNSKKRTSLNYCNSEKVLLDHQQFPSLEAFDAVVNNYLQNLSSKKRDKALVDNHRYSLILQVLKDPRNTAISTAQFRFWVKKMFCLSKTPDHIEFVCHDNKPVATREDIYHILIAAHKEAHHGGRDKTSALVRKRYSWIPKELIARFVRHCPFCLSRRNGTQQQSTSSACFSKKRIDKVAYQPYYPNASISIAATVATSAAVAAVTSSLLAPSPPLDNNLDFYYPHTALATATVGATETTLINEQILSSPKPSRLFNRYLNHSADAAAAVVAAAAIAAATQQHNTSLSSSQNCFSQDSTIADLKSCILPTPTSCAFYSSNRNHSILLSPSSPDSCS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NJ19</accession>
    <name>A0A1C7NJ19_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Guanine nucleotide-binding protein-like 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">GNL1</name>
        <name evidence="7" type="ORF">A0J61_02973</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Possible regulatory or functional link with the histocompatibility cluster.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000120">
        <property type="protein sequence ID" value="OBZ88990.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NJ19"/>
    <dbReference type="STRING" id="101091.A0A1C7NJ19"/>
    <dbReference type="InParanoid" id="A0A1C7NJ19"/>
    <dbReference type="OrthoDB" id="61815at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01857">
        <property type="entry name" value="HSR1_MMR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043358">
        <property type="entry name" value="GNL1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006073">
        <property type="entry name" value="GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45709:SF3">
        <property type="entry name" value="GUANINE NUCLEOTIDE-BINDING PROTEIN-LIKE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45709">
        <property type="entry name" value="LARGE SUBUNIT GTPASE 1 HOMOLOG-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01926">
        <property type="entry name" value="MMR_HSR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00326">
        <property type="entry name" value="GTP1OBG"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="G" evidence="6">
        <location>
            <begin position="312"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00037770"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00039902"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OBZ88990.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="522" mass="60806" checksum="2D5A968A3772450D" modified="2016-11-30" version="1">MSSLSDHFVSASGQDHATPSDFSHTPSRSTKLVSVFERLSSVEIEREKQKSMQPLHRLPKDNLEIQPEEFNQTIEFPKRPAWNYEMSKEQVEQREQESFDSWMKQIEETYGQDQQLSWFERNLEVWRQLWRVLEISDVIVLVMDIRNPLLHFPRSLYHYVTQTLKRKMIGVFNKVDLVAEFTVFAWRKYFEEQFPELHIATFSCYPRDSKLIDDTTTYALKNQAKRPKKRYYYAQGVKDILGLCRDVIDKPDVQVDWHTMIAQYDHSQEEMEYDDSDSDSDTGSMDGLDDEFSRILEITGQEIKPHHDYITLGLVGHPNVGKSSLINSIMKRTVVSASRTPGHTKHFQTIHISPHVRLCDSPGLVFPALIPKTLQILSGMYPIAQVQEPYSAIRYLAERIPLEKVLSLTPPCEFQDMKHYQWTTWSICEQFAEQRGFFTAKAARPDVYRAANTILRLTTDGRILLSFKPPGFFHSTKYEKLRVIEADKASPDDTEDEEEEEERENLLVSKGGRFNVLVDFEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NJ44</accession>
    <name>A0A1C7NJ44_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">SUMO-conjugating enzyme UBC9</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Ubiquitin carrier protein 9</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="10">Ubiquitin-conjugating enzyme E2-18 kDa</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="primary">hus5</name>
        <name evidence="14" type="ORF">A0J61_02936</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="2">Protein modification; protein sumoylation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="12">Belongs to the ubiquitin-conjugating enzyme family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000118">
        <property type="protein sequence ID" value="OBZ89028.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NJ44"/>
    <dbReference type="FunCoup" id="A0A1C7NJ44">
        <property type="interactions" value="1191"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NJ44"/>
    <dbReference type="InParanoid" id="A0A1C7NJ44"/>
    <dbReference type="OrthoDB" id="6600758at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005694">
        <property type="term" value="C:chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019787">
        <property type="term" value="F:ubiquitin-like protein transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016925">
        <property type="term" value="P:protein sumoylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd23798">
        <property type="entry name" value="UBCc_UBE2I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.110.10:FF:000035">
        <property type="entry name" value="SUMO-conjugating enzyme ubc9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.110.10">
        <property type="entry name" value="Ubiquitin Conjugating Enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050113">
        <property type="entry name" value="Ub_conjugating_enzyme"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000608">
        <property type="entry name" value="UBC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023313">
        <property type="entry name" value="UBQ-conjugating_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016135">
        <property type="entry name" value="UBQ-conjugating_enzyme/RWD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24067">
        <property type="entry name" value="UBIQUITIN-CONJUGATING ENZYME E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00179">
        <property type="entry name" value="UQ_con"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00212">
        <property type="entry name" value="UBCc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54495">
        <property type="entry name" value="UBC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00183">
        <property type="entry name" value="UBC_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50127">
        <property type="entry name" value="UBC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 12" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 12" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="5 12" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="UBC core" evidence="13">
        <location>
            <begin position="5"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="active site" description="Glycyl thioester intermediate" evidence="11">
        <location>
            <position position="97"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004718"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00039165"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00044296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00081544"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU362109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="OBZ89028.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="161" mass="18699" checksum="9FD091A175F108BD" modified="2016-11-30" version="1">MSSGISRSRLMEERKQWRKDHPHGFWARPGKNPDNSLDLMNWTCGIPGKEDTPWEKATYKLTMIFPEGWLNYPSKPPKCKFTPPLFHPNVYPSGTVCLSILNEDEGWKPAITVKQILLGVQDLLNDPNPESPAQQEAYMLFRKDKKEYERRVREQALANRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NJ81</accession>
    <name>A0A1C7NJ81_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Microtubule-associated protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">MAPT</name>
        <name evidence="8" type="ORF">A0J61_03100</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Cytoplasm</location>
            <location evidence="1 6">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000128">
        <property type="protein sequence ID" value="OBZ88849.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NJ81"/>
    <dbReference type="STRING" id="101091.A0A1C7NJ81"/>
    <dbReference type="InParanoid" id="A0A1C7NJ81"/>
    <dbReference type="OrthoDB" id="206213at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008017">
        <property type="term" value="F:microtubule binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000226">
        <property type="term" value="P:microtubule cytoskeleton organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027324">
        <property type="entry name" value="MAP2/MAP4/Tau"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001084">
        <property type="entry name" value="MAP_tubulin-bd_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11501">
        <property type="entry name" value="MICROTUBULE-ASSOCIATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11501:SF18">
        <property type="entry name" value="MICROTUBULE-ASSOCIATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00418">
        <property type="entry name" value="Tubulin-binding"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00229">
        <property type="entry name" value="TAU_MAP_1"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51491">
        <property type="entry name" value="TAU_MAP_2"/>
        <property type="match status" value="8"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 6" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="6" id="KW-0493">Microtubule</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="410"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="32"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="59"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="109"/>
            <end position="124"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000686"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OBZ88849.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="453" mass="49581" checksum="7DDA5CF7B4D28B5A" modified="2016-11-30" version="1">MSPTPVNERRRSIASRMTQTSIRIGSEPFIPPSSRSSSRSSSRSSHIPSPSKSNKTNKEQSTSSIPKRTSSTPTSANEASHEVARPPLPPIPVEYSQESIAKCAPNKKLSASKSYTTKRASMVSTPPPVPSDFSHVKSKIGSLENAKHKPGGGKKKVFDEKIDNLKERIISKVSSKVGSKDNLKHKPGGGEVKIFDDKLEFIKSKEIKSKIGSKDNIKHKPGGGEVKIFDDKLEFIKSKQITPKVGSKDNIKHKPGGGEVKIFDDKLEFIKSKEIKSKVGSKENIKHKPGGGEVKIFDDKLEFIKSKQIAPKVGSKDNIKHKPGGGEVKIFDDKSVFDISKEAKPKVGSLENAKHKPGGGDLYIYDDKGGFLNIDEIIPKVGSKDNIKHKPGGGDLYIYDEKLMFKETASPRIDAGKSRRTSMYGIASPALTNEEDDKEEGERQPYVLSPISI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NJM1</accession>
    <name>A0A1C7NJM1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="14">Multidrug resistance protein 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">PGY2_0</name>
        <name evidence="14" type="ORF">A0J61_03284</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ABC transporter superfamily. ABCB family. Multidrug resistance exporter (TC 3.A.1.201) subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000138">
        <property type="protein sequence ID" value="OBZ88676.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="FunCoup" id="A0A1C7NJM1">
        <property type="interactions" value="20"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NJM1"/>
    <dbReference type="InParanoid" id="A0A1C7NJM1"/>
    <dbReference type="OrthoDB" id="6500128at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015421">
        <property type="term" value="F:ABC-type oligopeptide transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090374">
        <property type="term" value="P:oligopeptide export from mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd18577">
        <property type="entry name" value="ABC_6TM_Pgp_ABCB1_D1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18578">
        <property type="entry name" value="ABC_6TM_Pgp_ABCB1_D2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03249">
        <property type="entry name" value="ABC_MTABC3_MDL1_MDL2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1560.10:FF:000009">
        <property type="entry name" value="ABC transporter B family member 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000205">
        <property type="entry name" value="ABC transporter B family member 4"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1560.10:FF:000018">
        <property type="entry name" value="ATP-binding cassette subfamily B member 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="entry name" value="ABC transporter type 1, transmembrane domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039421">
        <property type="entry name" value="Type_1_exporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43394">
        <property type="entry name" value="ATP-DEPENDENT PERMEASE MDL1, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43394:SF27">
        <property type="entry name" value="ATP-DEPENDENT TRANSLOCASE ABCB1-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="ABC transporter transmembrane region"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="9 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="90"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="140"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="216"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="241"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="320"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="357"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="750"/>
            <end position="775"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="795"/>
            <end position="821"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="13">
        <location>
            <begin position="94"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="12">
        <location>
            <begin position="418"/>
            <end position="655"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="13">
        <location>
            <begin position="753"/>
            <end position="1041"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="12">
        <location>
            <begin position="1077"/>
            <end position="1319"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="10">
        <location>
            <begin position="653"/>
            <end position="733"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007577"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="OBZ88676.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="1325" mass="145955" checksum="BA23CB50F76C3014" modified="2016-11-30" version="1">MADTSISSRSTTADQFYEEKIVTTTKTDSNEHNDEKILLEQEIAAIPIKQLESKHADEKEDTDKKKKKKKEKQPSVPIYKLFRFATPLELCMIAISAIFSMGVGALQPVSIIIFGDFMGTISTSMVTGDLAQLVEDVHPLILIFVYMGTGVLVAAYITNCFWILTGENQVRRIRNMYVHAILRQEMGWFDKAEEGSLTTRLATDTQLIQDGISEKFGLLLMCVGQFITGFIVAFVKGWRLAVVMLATLPVLAGVGGAMGYFITKYTLKAQDSYADAGSIAEQVFSGIRTVYSFSLQSRFAALYDSKLIKAMQTGVKRGQVIGFGFGTFMFTLFATYGLAFWYGSKLTREDLMAGQDVLVVFFAMIMGAIALLQLPPNLSAVSSACGAAYKIYSTIDRVPPIDVDQMGGLAPEKVLGEIEFKNVKFSYPTRPDITILKQLNLKIKPGMTVAFVGPSGSGKSTSVQLLQRFYDPLEGSVILDGKDLKEYNVAWLRSQIGVVSQEPVLFNMTIKQNLLMGVTKEVSNDEIVTACKKANCHTFISQLPDGYETLVGEHGGMLSGGQKQRIAIARAILKNPTILLLDEATSALDTQSERLVQAALDAAAADRTTIVIAHRLSTIRNADLIVVMQAGDLVEQGNHNDLLALNGVYADLVKKQEISTKQANSDVDELNSEELLKREQQELIAEKKRAEEELVNEKDTTVNLFKTTSRASVDALELKLRKEKEERKLAMKQSAPIGKVLKQMKPEWPLLMLGVAGAMIAGAVFPCFALIFSRVLSTLISPDKVPPGPLEGTNLYAFLFVIIGIAAFIGFSAQVISFEVAGERYTKRLRGEIFRAFMRQEIGYFDEDDNSLGALTSKLAIDSKNVNELVTKTWGDITQIIVTAITGLAIAFSQSWMLTLIILCMAPFIGFATFYESKIHRGFEDKTKKANEQSGEVAGEAIKEIRTVAGLNKQNYFENKYHVATDRPHQLAQRKAYTSSLGYAMQQGIILYTNAVAFYAGTQLMYHHGLSFEKMFTCMMTIMITAQGVGRASVFTTTYAKAKYSSIAAFEVLERQPSIDPELEGIEPDRSQIRGDIDFKDITFRYPARPDVSIFNGEFNLSGKAGQTIALVGPSGCGKSTTIGMLQRWYDPIAGTVRLDDSNVKSYTLGNLRSHTSLVGQEPVLFDMTIGENIRFGVDEGKEVTQEEVENAAKAANIHKFIVSLPDGYNTRVGDKGSQLSGGQKQRIAIARALIRKPKVLLLDEATSALDSESEKLVQAAIDNILEEGGRTTITIAHRLSTIQNADLICVVKNGRVIEQGTHWELLKLNGTYSELVYQQSLNAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NK82</accession>
    <name>A0A1C7NK82_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">2'-5' RNA ligase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_03036</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000124">
        <property type="protein sequence ID" value="OBZ88906.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NK82"/>
    <dbReference type="InParanoid" id="A0A1C7NK82"/>
    <dbReference type="OrthoDB" id="2110229at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1140.10">
        <property type="entry name" value="Cyclic phosphodiesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ88906.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="184" mass="21335" checksum="C8C289E015D53864" modified="2016-11-30" version="1">MRELIIYLEPPVGLKQTIQSFLDDSRDKFGWTTANKYNCHVSMSGFFTVTEPDRVLECIQSTLPKAHTILIDMKPLLVDNHHLLLPITAPPSLHTMMTQVADQCQDIAHIRIKKINHISLAYWDDNTHDEAILKQITKQATSYFSNLCQEEGVWDIVLYERTKKSQAITEVHQFRELKRWPLSC</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NKK1</accession>
    <name>A0A1C7NKK1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Forkhead protein sep1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">sep1_1</name>
        <name evidence="6" type="ORF">A0J61_02286</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000084">
        <property type="protein sequence ID" value="OBZ89651.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NKK1"/>
    <dbReference type="STRING" id="101091.A0A1C7NKK1"/>
    <dbReference type="InParanoid" id="A0A1C7NKK1"/>
    <dbReference type="OrthoDB" id="5954824at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009653">
        <property type="term" value="P:anatomical structure morphogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030154">
        <property type="term" value="P:cell differentiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00059">
        <property type="entry name" value="FH_FOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.10:FF:000135">
        <property type="entry name" value="forkhead box protein G1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001766">
        <property type="entry name" value="Fork_head_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050211">
        <property type="entry name" value="FOX_domain-containing"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018122">
        <property type="entry name" value="TF_fork_head_CS_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030456">
        <property type="entry name" value="TF_fork_head_CS_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11829:SF343">
        <property type="entry name" value="FORK-HEAD DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11829">
        <property type="entry name" value="FORKHEAD BOX PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00250">
        <property type="entry name" value="Forkhead"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00053">
        <property type="entry name" value="FORKHEAD"/>
    </dbReference>
    <dbReference type="SMART" id="SM00339">
        <property type="entry name" value="FH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00657">
        <property type="entry name" value="FORK_HEAD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00658">
        <property type="entry name" value="FORK_HEAD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50039">
        <property type="entry name" value="FORK_HEAD_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2 3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fork-head" evidence="5">
        <location>
            <begin position="44"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="Fork-head" evidence="3">
        <location>
            <begin position="44"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="136"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="213"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="136"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="156"/>
            <end position="190"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50039"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OBZ89651.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="399" mass="44859" checksum="B65732C5FC575882" modified="2016-11-30" version="1">MVSTTSMKRKNASTDQCTYDASNLPSSGPLHIVPSWKPINRAEKPPYSYATIIGHAILSSKERKLTLHDIYIWITQNYPFYSNDTQGWQNSIRHNLSLHKAFVKIDRDPNAQNPPRKGCFWTIRQGKEKMFIDNLQRPSNSARKQYPLTQHHSSRRQYYSSRRSSSALSTASSASSCQSKTSNMTTTESSTTEVCATSSVSFGLPESEPIVVSSSSTSPLLSASSSSSSPVITTEPSYNQLFSNVPESTNVSYNVYPENTSELFGDFYPSMYLPETGQPSCDAYSTTSSLTDNLMPAAYYSPIQNSPDMQAYAFEQPHTVLYDPVHYSSSFNYMENDGNMMADWDMSHHHQQDDCPMMTILKHQGNPYFDSNTDSTLISPTYYQHLQSSHQDTLGPFHR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NKU6</accession>
    <name>A0A1C7NKU6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Thioredoxin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">trx1_1</name>
        <name evidence="6" type="ORF">A0J61_02183</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the thioredoxin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000079">
        <property type="protein sequence ID" value="OBZ89757.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NKU6"/>
    <dbReference type="FunCoup" id="A0A1C7NKU6">
        <property type="interactions" value="314"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NKU6"/>
    <dbReference type="InParanoid" id="A0A1C7NKU6"/>
    <dbReference type="OrthoDB" id="2121326at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015035">
        <property type="term" value="F:protein-disulfide reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02947">
        <property type="entry name" value="TRX_family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.30.10:FF:000245">
        <property type="entry name" value="Thioredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005746">
        <property type="entry name" value="Thioredoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017937">
        <property type="entry name" value="Thioredoxin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01068">
        <property type="entry name" value="thioredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46115">
        <property type="entry name" value="THIOREDOXIN-LIKE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00085">
        <property type="entry name" value="Thioredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000077">
        <property type="entry name" value="Thioredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00421">
        <property type="entry name" value="THIOREDOXIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00194">
        <property type="entry name" value="THIOREDOXIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 4" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="4" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin" evidence="5">
        <location>
            <begin position="1"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="3">
        <location>
            <position position="31"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="3">
        <location>
            <position position="34"/>
        </location>
    </feature>
    <feature type="site" description="Deprotonates C-terminal active site Cys" evidence="3">
        <location>
            <position position="25"/>
        </location>
    </feature>
    <feature type="site" description="Contributes to redox potential value" evidence="3">
        <location>
            <position position="32"/>
        </location>
    </feature>
    <feature type="site" description="Contributes to redox potential value" evidence="3">
        <location>
            <position position="33"/>
        </location>
    </feature>
    <feature type="disulfide bond" description="Redox-active" evidence="4">
        <location>
            <begin position="31"/>
            <end position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRNR" id="PIRNR000077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR000077-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR000077-4"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OBZ89757.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="105" mass="11754" checksum="AE9FD74734A21097" modified="2016-11-30" version="1">MSFQEPKNLSEFQALINQDKLVIVDFHATWCGPCKLIAPKLKNFAESYTDVVFAKVDVDEVPDVAGEYQVRAMPTIMYFKNGQKLDEVVGANVKSIEDKLKALTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NL23</accession>
    <name>A0A1C7NL23_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_02132</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000076">
        <property type="protein sequence ID" value="OBZ89831.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NL23"/>
    <dbReference type="InParanoid" id="A0A1C7NL23"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ89831.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="59" mass="6712" checksum="14076F37391DC2FA" modified="2016-11-30" version="1">MSLDRIFFEDPCQTICAADYSPLSFYYGLNGSCPNLDIKPVSTDSERGLVYLVQEQLRM</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NLC7</accession>
    <name>A0A1C7NLC7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">General negative regulator of transcription subunit 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">not2</name>
        <name evidence="6" type="ORF">A0J61_02030</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CNOT2/3/5 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000072">
        <property type="protein sequence ID" value="OBZ89907.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NLC7"/>
    <dbReference type="FunCoup" id="A0A1C7NLC7">
        <property type="interactions" value="59"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NLC7"/>
    <dbReference type="InParanoid" id="A0A1C7NLC7"/>
    <dbReference type="OrthoDB" id="25391at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030015">
        <property type="term" value="C:CCR4-NOT core complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000289">
        <property type="term" value="P:nuclear-transcribed mRNA poly(A) tail shortening"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.1020">
        <property type="entry name" value="CCR4-NOT complex subunit 2/3/5, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038635">
        <property type="entry name" value="CCR4-NOT_su2/3/5_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040168">
        <property type="entry name" value="Not2/3/5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007282">
        <property type="entry name" value="NOT2/3/5_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23326">
        <property type="entry name" value="CCR4 NOT-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04153">
        <property type="entry name" value="NOT2_3_5_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="NOT2/NOT3/NOT5 C-terminal" evidence="5">
        <location>
            <begin position="209"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="129"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="346"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="20"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="146"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="156"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="347"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="361"/>
            <end position="379"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF04153"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OBZ89907.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="379" mass="42255" checksum="0F2C33B6CD2C43B4" modified="2016-11-30" version="1">MFRPNTTADLNEFPALGTPPTLNRSMNNRLGTSYASTAGNNGFQQQQQQQQQGASEIEDLKNNLAFNRGNFSNNNNQPRSFSMDEFPALRSSAVPFDNAIGGRDAVNNSTVAGGVNKPEQWLDYANLRESQPQGKPFPDTKAAPGSSESWIQSRKSTQDEVNDGKSTDPYGLLGLLGVIRMTDPDRSMLALGSDLTTLGLDLNTSDSIYSTFISPWSDTQTLPGLNVEPGYYLPACYRNVQATPPAHQRMRTFSDEILFYVFYCMPKDIAQEAAAQELYARNWRYHKELGLWLTKETDENGRPVQSFRRTSPNALDRGVYVFFDPTTWQKVKREWTLSWDAIEERSQPATTTSNQVSTNQASTSPGANSSSSNTNRMMM</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NLI2</accession>
    <name>A0A1C7NLI2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_02228</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000081">
        <property type="protein sequence ID" value="OBZ89719.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NLI2"/>
    <dbReference type="InParanoid" id="A0A1C7NLI2"/>
    <dbReference type="OrthoDB" id="2280111at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ89719.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="451" mass="52281" checksum="EC152AB15DD06100" modified="2016-11-30" version="1">MYTKQLPVEITREIFTYILLQHNSETSTKKESIPPCRYIPRRTSLYPNHAQSRFFRYGEDGQCICWQIDMLNVAMVCWSWYLISMEIMQSHHVLSLQDLRYSHSQPAPWLSLINYPSYKRNYPFRKKLVQILKDSQRANLAFNHQLSHLVIDFASFDTIRTEPSKSSRVLTKRKVHHSHQLHQLTELIQLCTQAQHLEIVCDAGHANLIGVSNQKKLSNSARVCNTDSLYSERNRILYASHQIRKAITKSGAAIRRLDFIGYNPIQRCPCCASKDWDQFLGPLIHVLSLETVVLQHVLPSIRLFEILADTQPQLRKLVFHKSMITRPKKTLTATEESQGFLTSISQIPRSLWKQLTCIEIYEDIEDANSWRSQRYLSELAECISPQLTEFVLQFETEEVNQKCLSALSTKEESHFSITKIDDLNSPLNAIVSKCHMLKRLKLVNVPKARLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NLQ2</accession>
    <name>A0A1C7NLQ2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Hybrid signal transduction histidine kinase J</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">dhkJ_3</name>
        <name evidence="5" type="ORF">A0J61_03705</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000165">
        <property type="protein sequence ID" value="OBZ88234.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NLQ2"/>
    <dbReference type="STRING" id="101091.A0A1C7NLQ2"/>
    <dbReference type="InParanoid" id="A0A1C7NLQ2"/>
    <dbReference type="OrthoDB" id="10266508at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06225">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="9"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.120.1530:FF:000002">
        <property type="entry name" value="Two-component osmosensing histidine kinase"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1530">
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.500">
        <property type="entry name" value="HAMP domain in histidine kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003660">
        <property type="entry name" value="HAMP_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45339">
        <property type="entry name" value="HYBRID SIGNAL TRANSDUCTION HISTIDINE KINASE J"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45339:SF1">
        <property type="entry name" value="HYBRID SIGNAL TRANSDUCTION HISTIDINE KINASE J"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00672">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18947">
        <property type="entry name" value="HAMP_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00304">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="10"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF58104">
        <property type="entry name" value="Methyl-accepting chemotaxis protein (MCP) signaling domain"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50885">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="9"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="2" id="KW-0902">Two-component regulatory system</keyword>
    <feature type="domain" description="HAMP" evidence="4">
        <location>
            <begin position="358"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="domain" description="HAMP" evidence="4">
        <location>
            <begin position="450"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="domain" description="HAMP" evidence="4">
        <location>
            <begin position="542"/>
            <end position="594"/>
        </location>
    </feature>
    <feature type="domain" description="HAMP" evidence="4">
        <location>
            <begin position="634"/>
            <end position="686"/>
        </location>
    </feature>
    <feature type="domain" description="HAMP" evidence="4">
        <location>
            <begin position="726"/>
            <end position="778"/>
        </location>
    </feature>
    <feature type="domain" description="HAMP" evidence="4">
        <location>
            <begin position="818"/>
            <end position="870"/>
        </location>
    </feature>
    <feature type="domain" description="HAMP" evidence="4">
        <location>
            <begin position="910"/>
            <end position="962"/>
        </location>
    </feature>
    <feature type="domain" description="HAMP" evidence="4">
        <location>
            <begin position="1002"/>
            <end position="1054"/>
        </location>
    </feature>
    <feature type="domain" description="HAMP" evidence="4">
        <location>
            <begin position="1094"/>
            <end position="1146"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="138"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="36"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="140"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="162"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="1163"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OBZ88234.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="1163" mass="125068" checksum="5EE886C8DE6D1690" modified="2016-11-30" version="1" fragment="single">MKRSSTGDNSPIIKKKVRDNTTEEEPITTDIFSPIPSANMTHTTHTASDSNTSPAGSMSVIRYVYGLVHNLEQGNIDHCLSHSIDSSQFDETLSAADTDLLNALDSNLKKIAQRQLQLETENLRSRIMIQQQHQLLTASNHEEKDHSESSKGPSQEDKERTTNTTPEDSLTSVHDSSLLEKLENSYREMPKIPQQKEKAKTSNNNDLAAGLASLSSPPPFTISSIATAYPVYFGSTSSSAISFPAAAVQTSSDNIVCPDCVIQAVTVACGVFNGDLNGRITCKHERCVAGTNVESDAPINTLKNAINAMADQLQGITDEVNSVAHETAVNGKLGIQCSIKEKKGLWKDFVVNLNLMTRNHLEQVRDIADVSQAIARGDLSKAMTAPVRGETLLLKNTFNTMVNQLNLFASEVSRVAHEVGTEGKLGAQAKVQGADGIWKELTDNVNTMAANLTNQVRDIAQVSKSVARGNLTKKVTVEVRGEMLDLKNTINTMVDQLSIFATEVTRVSLEVGTEGKLGGQAIVKDVAGTWKDLTDNVNTMATRLTDQMRDIAVVAKAVAQGDLSKKVKANAQGEVLELKNTMNKMVDQLLLFSAEVRRVSLEVGVEGKLGGQAVVKDVGGTWKNLTDNVNQMAANLTNQVRSIAEVTKAVANGDLSKKIEVETRGEILDLKNTVNDMVDQLRVFASEVTRVSREVGTEGKLGGEAIVPSVSGTWKDLTDNVNTMAANLTTQVRSIAEVTKAVAKGDLSKKIYVETQGEILDLKNTVNNMVDQLNVFAAEVTRVAKEVGTEGKLGGQALVPNVDGTWMDLTVNVNHMATNLTNQVRSIAEVTKAVALGDLSKKIEVESGGEILDLKNIVNNMVDQLRVFASEVTRVSKEVGTEGKLGGQAVVQGVAGTWNELTVNVNHMATNLTNQVRSIAEVTKAVALGDLSKKIEVESGGEILDLKNIVNNMVDQLRVFASEVTRVSKEVGTEGKLGGQAMVPNVAGTWFELTDNVNIMAANLTNQVRSIAEVTKAVALGDLSKKIEVESGGEILDLKNIVNNMVDQLRIFASEVTRVSKEVGTDGKLGGQARVPNVAGTWYELTSNVNIMAANLTTQVRSIAEVTKAVALGDLSKKIEVESGGEILDLQNIVNNMVDQLNVFASEVSRVAREVGTEGKLGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NN30</accession>
    <name>A0A1C7NN30_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Xaa-Pro dipeptidyl-peptidase-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_01689</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000056">
        <property type="protein sequence ID" value="OBZ90279.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NN30"/>
    <dbReference type="STRING" id="101091.A0A1C7NN30"/>
    <dbReference type="InParanoid" id="A0A1C7NN30"/>
    <dbReference type="OrthoDB" id="10260961at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000383">
        <property type="entry name" value="Xaa-Pro-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42103:SF2">
        <property type="entry name" value="AB HYDROLASE-1 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42103">
        <property type="entry name" value="ALPHA/BETA-HYDROLASES SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02129">
        <property type="entry name" value="Peptidase_S15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Xaa-Pro dipeptidyl-peptidase-like" evidence="1">
        <location>
            <begin position="31"/>
            <end position="136"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02129"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ90279.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="228" mass="25713" checksum="10FEF608426764CF" modified="2016-11-30" version="1">MLSQNIFVESIEDKIPIEVGISANITSQQLQTSPGIIIAHPYGPLGGNRWNNVVIALQRYFTSKGYVVFCLNFRGCGKSKGKTSWTAMPERQDYQAVIDYALDHPLPEIPKIDRLVLCGYSFGAMIASTMICTRVPCAYLLISIPLGVLWALATTKSSFFKQVPTIDSRRILCIHGGRDQFTRSSRIQQLYPSDSVHIIEEADHFWFDLEFAIIDKVAQWNSSLEYDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NNC3</accession>
    <name>A0A1C7NNC3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Putative MFS-type transporter PB1E7.08c</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">A0J61_01319</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000040">
        <property type="protein sequence ID" value="OBZ90633.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NNC3"/>
    <dbReference type="FunCoup" id="A0A1C7NNC3">
        <property type="interactions" value="165"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NNC3"/>
    <dbReference type="InParanoid" id="A0A1C7NNC3"/>
    <dbReference type="OrthoDB" id="3936150at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd17316">
        <property type="entry name" value="MFS_SV2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23511:SF5">
        <property type="entry name" value="MAJOR FACILITATOR-TYPE TRANSPORTER HXNZ-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23511">
        <property type="entry name" value="SYNAPTIC VESICLE GLYCOPROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="73"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="110"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="144"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="197"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="246"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="383"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="424"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="455"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="479"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="519"/>
            <end position="537"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="544"/>
            <end position="562"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="58"/>
            <end position="566"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OBZ90633.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="572" mass="63732" checksum="7D0C67767202CACD" modified="2016-11-30" version="1">MALHQSSDREFAPMQTDEEAADIVKEQNEHSTPEQILDGLLSKVGYGLFQKKLLVSMRERVVVLGVKELKYNLLLLQILCGFGWLADNTIAIILPRVQVELDHYSVSDKWIGVLSSSLFAGMTFGAFFWGTYSDSRGRKLPYTMTLAITTIFGLISSFTFNFGSLCFALFFLGFGVGGNMPTDGALYLEFLPREFHYLLTFMSVFFSFGAVFASVLGYLILPKWSCPETIPLELCDVQTQNKGWRILLFAVSVITLAMLILRSLWVRLPETPKFLMSQDRQNETIIVLQDIARINGGAIQIKKEELPNMQRRSRSNSPSQSMNEDEDYILSQTNYEDEDDVNRVLLSEQYSNTDETTLSSENEKGKDQAYKLLLSPQWRLTTLLIWAIWTLTSVAYTVFNVFLPKFLENMGFQGESTPSREQVYLDYMIYSLSGVPGSVIASWLIETRLGRKGTMAASAFGSSLSLFIFSIISSRFTMVASSSAVSFLATLLYAVIYGYTPEVFDTNVRGTAVGTASGLGRVAGIISPIMSGILLTINISLPLYVSVVGFAIVGVCVVLLPYETRSKKPSTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NP17</accession>
    <name>A0A1C7NP17_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">Presenilin</fullName>
            <ecNumber evidence="15">3.4.23.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="primary">psen2_0</name>
        <name evidence="18" type="ORF">A0J61_01066</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18 19">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Probable catalytic subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Requires the other members of the gamma-secretase complex to have a protease activity.</text>
    </comment>
    <comment type="function">
        <text evidence="15">Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors.</text>
    </comment>
    <comment type="subunit">
        <text evidence="13">Homodimer. Component of the gamma-secretase complex, a complex composed of a presenilin homodimer, nicastrin, aph1 and pen2.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="15">Endoplasmic reticulum membrane</location>
            <topology evidence="15">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="15">Golgi apparatus membrane</location>
            <topology evidence="15">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="15">The PAL motif is required for normal active site conformation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 15">Belongs to the peptidase A22A family.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.23.-" evidence="15"/>
    <dbReference type="EMBL" id="LUGH01000030">
        <property type="protein sequence ID" value="OBZ90881.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NP17"/>
    <dbReference type="STRING" id="101091.A0A1C7NP17"/>
    <dbReference type="InParanoid" id="A0A1C7NP17"/>
    <dbReference type="OrthoDB" id="432970at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070765">
        <property type="term" value="C:gamma-secretase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042500">
        <property type="term" value="F:aspartic endopeptidase activity, intramembrane cleaving"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044351">
        <property type="term" value="P:macropinocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006509">
        <property type="term" value="P:membrane protein ectodomain proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016485">
        <property type="term" value="P:protein processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.472.100:FF:000003">
        <property type="entry name" value="Presenilin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.2220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.100">
        <property type="entry name" value="Presenilin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001108">
        <property type="entry name" value="Peptidase_A22A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006639">
        <property type="entry name" value="Preselin/SPP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042524">
        <property type="entry name" value="Presenilin_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002893">
        <property type="entry name" value="Znf_MYND"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10202">
        <property type="entry name" value="PRESENILIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10202:SF13">
        <property type="entry name" value="PRESENILIN HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01080">
        <property type="entry name" value="Presenilin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01072">
        <property type="entry name" value="PRESENILIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00730">
        <property type="entry name" value="PSN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144232">
        <property type="entry name" value="HIT/MYND zinc finger-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50865">
        <property type="entry name" value="ZF_MYND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 15" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="10 15" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="5 15" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="11 15" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8 15" id="KW-0914">Notch signaling pathway</keyword>
    <keyword evidence="15" id="KW-0645">Protease</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 15" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 15" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 14" id="KW-0863">Zinc-finger</keyword>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="186"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="216"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="246"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="297"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="456"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="486"/>
            <end position="516"/>
        </location>
    </feature>
    <feature type="domain" description="MYND-type" evidence="17">
        <location>
            <begin position="33"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="357"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="400"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="16">
        <location>
            <begin position="357"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="16">
        <location>
            <begin position="413"/>
            <end position="426"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022976"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00053367"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00066080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="RuleBase" id="RU361148"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS50865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="OBZ90881.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="517" mass="57807" checksum="F551206E0123A035" modified="2016-11-30" version="1">MNRFVDKKQRKKKVGKEVMTSSLQEVTLESNVCSQCQKPATFMCSSCSHDGPKYCSVECQKTHWTACHYKECKASRSKRRARQQLNQNENIPLHDLSMDQTLTEQEKSKIEQEEEEAEELHFYTNQIYRIIKPVVACIILSIFWVKVSFSDQSDYSPVRTGYITVSSSTATTSSNSSSSSSSSPNIASSFTNAAIIIGQIIVVTIIIGWIKVLIGFFMLVVLSLLGFMTYILLLNLVQVFAIPLDYVTLVFALWNFAAVGLVSIFWKGPLWLQQAYLTIMSSLMAFSLTGLEQWTTWILLGLLAIWDLIAVLCPFGPLRLLLESSKKQQREVPALLYTVNAVWFMMASADQLRQLEPTSSKQINQRRSASSSYSPSNFIRKSHDGFMRLPDHDLPTQMDSLPANPDPIVTTDPKPEAEKAKNSTHDDDQESSGLKLGLGDFVFYSVLIARAAMYDWITTACCTIAVLTGLTATIFLLAIYKKALPALPISIAFGILFYFVAKTVLVPYVAALCVFVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NP74</accession>
    <name>A0A1C7NP74_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_01145</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000033">
        <property type="protein sequence ID" value="OBZ90808.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NP74"/>
    <dbReference type="InParanoid" id="A0A1C7NP74"/>
    <dbReference type="OrthoDB" id="2407359at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ90808.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="182" mass="20942" checksum="87B9F0E2C43425AE" modified="2016-11-30" version="1">MSIRFEIEGQGARIITPPLLNKKITLGSSDNTSRWVFYGTRPQILEWIENHQDIQLENNLFSQGRPLTYQTHTEVVIDLQSYSDPDQSLFSYLSSFVATDFIHEKVKVEIRPRVESKDQLISHLCRIVVASGVRLGDILTELNRIWYQPSPSFIEQANDLINDQPRPIHILSTDAPMHIQVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NP84</accession>
    <name>A0A1C7NP84_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_01231</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000037">
        <property type="protein sequence ID" value="OBZ90709.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NP84"/>
    <dbReference type="InParanoid" id="A0A1C7NP84"/>
    <dbReference type="OrthoDB" id="4325529at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="60"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="106"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="unsure residue" description="D or N" evidence="2">
        <location>
            <position position="229"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="276"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ90709.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="276" mass="31257" checksum="83EC2D26ED439D89" modified="2016-11-30" version="1" fragment="single">MQGSLSNNRNQTKQPYASSSAFRDDQQHFAPLPTVQTDYAQAMNQHYAYAQXVEAAAQDTAEKARNNRPKNTIKSYESKKKKSLRWCHTHCPPVPLNEIVVNREYKKKGTKRNRSLESSEEAPAASQDTTTLLPFDSDLVHLEEIETAAFENDELALEMQIRVVVGAPNRRVGLATVKVYIAAVVDLYNEQALAGPHSHRPHPRGKLVEALLRLLEXEQQKHRXENYVDXGVGTXADGYSTTAEMEKLXQYYFEKNTQEDLCDGVTFLLQHYGLLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NPW0</accession>
    <name>A0A1C7NPW0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Glutamine synthetase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">glnA_0</name>
        <name evidence="5" type="ORF">A0J61_02658</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the glutamine synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000103">
        <property type="protein sequence ID" value="OBZ89284.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NPW0"/>
    <dbReference type="STRING" id="101091.A0A1C7NPW0"/>
    <dbReference type="InParanoid" id="A0A1C7NPW0"/>
    <dbReference type="OrthoDB" id="415358at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004356">
        <property type="term" value="F:glutamine synthetase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006542">
        <property type="term" value="P:glutamine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1560">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.590.10">
        <property type="entry name" value="Glutamine synthetase/guanido kinase, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040577">
        <property type="entry name" value="Gln-synt_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008147">
        <property type="entry name" value="Gln_synt_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014746">
        <property type="entry name" value="Gln_synth/guanido_kin_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008146">
        <property type="entry name" value="Gln_synth_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027303">
        <property type="entry name" value="Gln_synth_gly_rich_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052725">
        <property type="entry name" value="GS_Type-3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022147">
        <property type="entry name" value="GSIII_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42974">
        <property type="entry name" value="GLUTAMINE SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42974:SF1">
        <property type="entry name" value="TYPE-3 GLUTAMINE SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00120">
        <property type="entry name" value="Gln-synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18318">
        <property type="entry name" value="Gln-synt_C-ter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12437">
        <property type="entry name" value="GSIII_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01230">
        <property type="entry name" value="Gln-synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55931">
        <property type="entry name" value="Glutamine synthetase/guanido kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00181">
        <property type="entry name" value="GLNA_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51986">
        <property type="entry name" value="GS_BETA_GRASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51987">
        <property type="entry name" value="GS_CATALYTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GS beta-grasp" evidence="3">
        <location>
            <begin position="91"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="domain" description="GS catalytic" evidence="4">
        <location>
            <begin position="197"/>
            <end position="645"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01330"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU000384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51986"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51987"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OBZ89284.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="753" mass="84174" checksum="6DCAF83FA319B01B" modified="2016-11-30" version="1">MAHQARINTVVESLTRGPRNVEFPSRNGQVKPVSEIFGQNVFSRSEMSKMLPKPVFKTFMETLKGKSTIDKVTADAIAHAAKVWAIEKGATHFTHWFQPLNDSTAEKHDSFLTLKTSSVDGSQVVTAIDTFSGSQLLQSEPDASSFPSGGMRTTFEARGYTVWDTKSPMFVQEGPHNTMVLYIPSVFISYNGEALDEKSVLLRSAEALERVALEVLKIIEPKDSENRSEYVYTTLGTEQEYFLIDRSLYTLRPDLKITGRTLIGGLPPRHQQLEDHYFGKIPTRVLSAISECELELAKLGVPIKTRHNEVAPAQFEVAPIFEEALMAVDHNLLTMDVLHRVAHRHKLKVLFHEKPFRGVNGSGKHCNWSMSTDKGDNLLEPSSNPENNYRFLIFLVATLKGVLDHGDLLRAGVASASNDHRLGAQEAPPGIISAFLGSQLTEVLNAIEEDRPVNQDGLELQHVRVKGTVLDLKVAALPPIARDLTDRNRTSPFAFTGNKFEFRAVGSKQSPSFPMTLLNSAVAKALTEILADLNEIKGDKPVASQEDQLTVIRKYIKLTKAIRFEGDNYSDEWVQEAAKRGLPNITKSPDAFARLLRKENVEMLRDMGVFSDAELNSRYHILVEKYAKDITIEAQTMITMVIQQVLPAAFEYRRNLAEAASFMKNVGVEASPEIDLLNELTPICATLQKDITALKYLMVDLIKVEDIVDLAKACCEQVLPKMESIRELADKLERNVADKLWPLPKYTELFLNI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NQX9</accession>
    <name>A0A1C7NQX9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_00420</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000009">
        <property type="protein sequence ID" value="OBZ91527.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NQX9"/>
    <dbReference type="STRING" id="101091.A0A1C7NQX9"/>
    <dbReference type="InParanoid" id="A0A1C7NQX9"/>
    <dbReference type="OrthoDB" id="2272914at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="111"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="257"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="337"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="215"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="257"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="348"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="374"/>
            <end position="383"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ91527.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="1015" mass="116329" checksum="34C0EA1C7CF30F9D" modified="2016-11-30" version="1">MAGADKDSIDGEDDIFQPKLPLVEEYNRDYVYHLNEDEIANDTIERMYGPFDSWYLDNGASTPTRKIKMPAKSVHDKKLEEIEKLKRDIREKEAQQRQAQEKRMALEKEIALDREKELQEARQQEEEEQDRQQKELKAHIEERIQHAVNEEVVADMEFSKGNNAHAAQNKEGGDAVSTKILEINTDATSDKDSYTTANDDSVHTEDIFIEKDEEEKLLDREIAELNARLQEVREEENQIQVKLLAMKVRISIEKNRKENNTVKDPKPELGTKRIKQQKSPVRSSKKKRHNEEAQNLGTPPPQPLPNFGYQLPVYFNTMQARPQYYLPNTAMMNQPYLPHPMSQSVPLSSPPPPPPPTDLPPPIPPPPPPPPPQTSQQTPSVRSRQSHKAKPATPYADMTHNDTHRVREYEATLAIFREIEQLISVRIFHSNQESDSSTSLLRIPPRPRRLITSEEYTVPINMFFLNKKYEADQQAPQKNSDFILPAGQPTKIELTDLTYESPLFIMLYRKAEGKKFDERMTSAINAAILCIPSEMDLSTFHVRHAYGLPLHPEKLSAMYQLAKAFCDDYKEKEFWGALKLELSMFVHGPTSIIFQKDFDATIKQFPLSVDVHWQGILSETTFVAQLARIKALLSDIYKSHGVYDSPESIAASAMTAEVLTRLVRLNGLTEVLKMLTGNERFEISLSGYTSFPLTETPGLYLLHNDKYYLWMLILYYFVMKSLPQGVCETWMNALVKEGRPQMNKPLFAIDWTETLLNNPLDKATLYGAVNILLSMWKHFSQLACNDSRKKPLLIGVLRTLVSFLMHTPQYKVPGTLLLVNKLTKVSLITPEIRELEIELEFKRNEDPKKLINLLFSITLHRPQSLALAYRCICLYGERAPYTNGFYAYTGCILAFPLANAKSDSEALLTFLDHHDMELVEHQYRHRLVQSLIDQYKGLVGMIPSSSPNAKSQEQAAFAWINLLLLTKILGAVNPEKQPEVRQEMDTIFHKGFSLINEYDGKLLFFKYASTLIAEH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NRY0</accession>
    <name>A0A1C7NRY0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Saccharopine dehydrogenase [NADP(+), L-glutamate-forming]</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">lys9</name>
        <name evidence="6" type="ORF">A0J61_00012</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000001">
        <property type="protein sequence ID" value="OBZ91885.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NRY0"/>
    <dbReference type="FunCoup" id="A0A1C7NRY0">
        <property type="interactions" value="393"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NRY0"/>
    <dbReference type="InParanoid" id="A0A1C7NRY0"/>
    <dbReference type="OrthoDB" id="10059875at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004755">
        <property type="term" value="F:saccharopine dehydrogenase (NADP+, L-glutamate-forming) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019878">
        <property type="term" value="P:lysine biosynthetic process via aminoadipic acid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.360.10:FF:000008">
        <property type="entry name" value="Alpha-aminoadipic semialdehyde synthase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000072">
        <property type="entry name" value="Saccharopine dehydrogenase [NADP(+), L-glutamate-forming]"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.360.10">
        <property type="entry name" value="Dihydrodipicolinate Reductase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1870.10">
        <property type="entry name" value="Domain 3, Saccharopine reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051168">
        <property type="entry name" value="AASS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032095">
        <property type="entry name" value="Sacchrp_dh-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005097">
        <property type="entry name" value="Sacchrp_dh_NADP-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11133:SF22">
        <property type="entry name" value="ALPHA-AMINOADIPIC SEMIALDEHYDE SYNTHASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11133">
        <property type="entry name" value="SACCHAROPINE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16653">
        <property type="entry name" value="Sacchrp_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03435">
        <property type="entry name" value="Sacchrp_dh_NADP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55347">
        <property type="entry name" value="Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="3" id="KW-0457">Lysine biosynthesis</keyword>
    <keyword evidence="1" id="KW-0521">NADP</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Saccharopine dehydrogenase NADP binding" evidence="4">
        <location>
            <begin position="6"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="domain" description="Saccharopine dehydrogenase-like C-terminal" evidence="5">
        <location>
            <begin position="125"/>
            <end position="443"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023154"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF03435"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF16653"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OBZ91885.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="450" mass="49492" checksum="A4FCC622AB6EF6ED" modified="2016-11-30" version="1">MVEKKILLLGSGFVAAPCVEYLARNPENKITIASRRLENAQALSKQYPGTVAVSCDINDESAIEKLVAEHDISISLIPYIYHAKVIKAAVKHKKNVVTTSYVSPAMLEYDQAAKDAGITVMNEIGLDPGIDHLYAVKTIEEVHREGGKLKEFISFCGGLPAPEDSNNPFGYKFSWSARGVLLALKNTAKYLEKGKVVEVSGTALMDSAKKLNTGYPGFAFVGYGNRDSTPYDKRYNIPEAETIIRGTIRYDGFCQFVKALVVLGFLSEEEEAHLSADAQDIAWNQVIAKTVGTQDTSAEALQAAIIQKCDLNNNDHKDQILDGMRWLGFFTNTPVHRRGSLLDTFCATLEEKMQYGENERDLVFLQHRFEIELKDGSHQTRTSTLVEYGKVGGFSAMAKTVGVPCGIATQLILDGKLTAVGVLAPMTNEINEPIMELLEKEGIGMVERIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NS57</accession>
    <name>A0A1C7NS57_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_00172</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000003">
        <property type="protein sequence ID" value="OBZ91810.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NS57"/>
    <dbReference type="InParanoid" id="A0A1C7NS57"/>
    <dbReference type="OrthoDB" id="2205937at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008889865" evidence="1">
        <location>
            <begin position="21"/>
            <end position="137"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ91810.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="137" mass="15282" checksum="C16C5CA3B4FB1362" modified="2016-11-30" version="1">MKSILTVFICLCLFAVNTLAYLAERSSPYTVTISNYQQAPIEVRKGDKIELQWNFAPGVRFPLYGYACPRTAKTDVGLLALNESSSRTQPYVYTISTGLSLLDNTFSWTVGDDVPSGEYRIGVGFFYHEATQSFVVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7LST2</accession>
    <name>A0A1C7LST2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transposon Tf2-9 polyprotein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">Tf2-9_1</name>
        <name evidence="2" type="ORF">A0J61_11912</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01002683">
        <property type="protein sequence ID" value="OBZ66979.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7LST2"/>
    <dbReference type="STRING" id="101091.A0A1C7LST2"/>
    <dbReference type="InParanoid" id="A0A1C7LST2"/>
    <dbReference type="OrthoDB" id="5592268at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015074">
        <property type="term" value="P:DNA integration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.10:FF:000032">
        <property type="entry name" value="Retrovirus-related Pol polyprotein from transposon 297-like Protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001584">
        <property type="entry name" value="Integrase_cat-core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050951">
        <property type="entry name" value="Retrovirus_Pol_polyprotein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37984">
        <property type="entry name" value="PROTEIN CBG26694"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37984:SF5">
        <property type="entry name" value="PROTEIN NYNRIN-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00665">
        <property type="entry name" value="rve"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50994">
        <property type="entry name" value="INTEGRASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Integrase catalytic" evidence="1">
        <location>
            <begin position="17"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="197"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50994"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ66979.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="197" mass="22431" checksum="5C48E4DE152FE9A0" modified="2016-11-30" version="1" fragment="single">MKNYVTTCVPCQLYGNINNKPKAKKVVTILRLFEQFSIDFVGPFPESTSGNKYIIVAVENFTRWPLAQACKKADAHTVANFIYEHIFVQFGPPTHLLSDNGAHFDNDVVEKFLHLLKIHHKFTSPYRPETNGMCERLNGTITQSLKKLSIQHPSAWDLHLPGIIYAYRTKAHGIIKISPFELLYGQPPRAPRQDALQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MPB4</accession>
    <name>A0A1C7MPB4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="1">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">PASK</name>
        <name evidence="10" type="ORF">A0J61_11855</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="1"/>
    <dbReference type="EMBL" id="LUGH01002591">
        <property type="protein sequence ID" value="OBZ78517.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MPB4"/>
    <dbReference type="STRING" id="101091.A0A1C7MPB4"/>
    <dbReference type="InParanoid" id="A0A1C7MPB4"/>
    <dbReference type="OrthoDB" id="10252171at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043066">
        <property type="term" value="P:negative regulation of apoptotic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007346">
        <property type="term" value="P:regulation of mitotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051138">
        <property type="entry name" value="PIM_Ser/Thr_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22984:SF11">
        <property type="entry name" value="AURORA KINASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22984">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE PIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 10" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="9">
        <location>
            <begin position="1"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="10">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OBZ78517.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="125" mass="14350" checksum="DAB2794C0A798577" modified="2016-11-30" version="1" fragment="single">IKDENIVIDQDYRVKLIDFGSSVLISRHAYLSRFYGTVSFASPEILMAQPYRAEPAEIWSLGVLLFTLLFGEIPFVDAKAAIDGRRMKSKFSVSDACQHLIDCLLRKNPEHRLTIHEVLKHPWFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MU27</accession>
    <name>A0A1C7MU27_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Serine/threonine-protein phosphatase</fullName>
            <ecNumber evidence="5">3.1.3.16</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">PPZ1_1</name>
        <name evidence="8" type="ORF">A0J61_11643</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10 5">
            <text>O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:47004"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="EC" id="3.1.3.16"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the PPP phosphatase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.16" evidence="5"/>
    <dbReference type="EMBL" id="LUGH01002291">
        <property type="protein sequence ID" value="OBZ80308.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MU27"/>
    <dbReference type="STRING" id="101091.A0A1C7MU27"/>
    <dbReference type="InParanoid" id="A0A1C7MU27"/>
    <dbReference type="OrthoDB" id="1930084at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004722">
        <property type="term" value="F:protein serine/threonine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050341">
        <property type="entry name" value="PP1_catalytic_subunit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006186">
        <property type="entry name" value="Ser/Thr-sp_prot-phosphatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031675">
        <property type="entry name" value="STPPase_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11668">
        <property type="entry name" value="SERINE/THREONINE PROTEIN PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11668:SF484">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN PHOSPHATASE PP-Z1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16891">
        <property type="entry name" value="STPPase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00114">
        <property type="entry name" value="STPHPHTASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00156">
        <property type="entry name" value="PP2Ac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="Metallo-dependent phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00125">
        <property type="entry name" value="SER_THR_PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0464">Manganese</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0904">Protein phosphatase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Serine/threonine specific protein phosphatases" evidence="7">
        <location>
            <begin position="212"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="56"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="223"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU004273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS00125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OBZ80308.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="223" mass="25572" checksum="C7EE63EF59DBA757" modified="2016-11-30" version="1" fragment="single">MGNSSSKGHSKRRPTNPPRQMGPAQQAPQPYNSLPPHKSNPSHHHQQKQQQQRQNGYYQSTGSKNSEYEVEQVLDDEDEEAYYHSHKNVMNDQHTHADIDSCIQRLLAAGKSRHIGKSVCLDQNEVIAICRYAYDLFLSQPSLLELNPGLKIVGDIHGQYFDLMRLFKMTGFPPSSNYLFLGDYVDRGMYSLETILLLLCFKIKYPENFFLLRGNHESADVTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MUB3</accession>
    <name>A0A1C7MUB3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Rax2-like C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_11510</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01002130">
        <property type="protein sequence ID" value="OBZ80441.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MUB3"/>
    <dbReference type="STRING" id="101091.A0A1C7MUB3"/>
    <dbReference type="InParanoid" id="A0A1C7MUB3"/>
    <dbReference type="OrthoDB" id="2503993at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902929">
        <property type="term" value="C:plasma membrane of growing cell tip"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.80">
        <property type="entry name" value="Kelch-type beta propeller"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011043">
        <property type="entry name" value="Gal_Oxase/kelch_b-propeller"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015915">
        <property type="entry name" value="Kelch-typ_b-propeller"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024982">
        <property type="entry name" value="Rax2-like_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31778">
        <property type="entry name" value="BUD SITE SELECTION PROTEIN RAX2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31778:SF2">
        <property type="entry name" value="BUD SITE SELECTION PROTEIN RAX2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12768">
        <property type="entry name" value="Rax2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50965">
        <property type="entry name" value="Galactose oxidase, central domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rax2-like C-terminal" evidence="1">
        <location>
            <begin position="81"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="381"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12768"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ80441.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="381" mass="40576" checksum="47B2D15EB2C27E71" modified="2016-11-30" version="1" fragment="single">MIAHAVQFIKDTSLGGMTSVLQYNTSSPMTTTKENVPWKILGENLPAQSVVKAMSTVDDSFYLGGTFSGTSKSNGTYVNFVQYDTTTNQLKSVPSNGFDGTVNAIACTTTDCFVGGSFNAFGANSTLTLNNVAQYNLQKAAWTDLEGGVDGNVDSIALLDSQVLVSGNFTHLQSTQSGVLGNALWNKELNKWASQNDSLPFLAGSIANVYGHGDVSYYLGGISHAQRYQSNGISFISSSSDNDVKLLPMDSFSPLDSNTSVISSGVLFKSNTTAENSTSTTILGGTFHLPNNIQNIAIYDQGEWSGIQGTDWQGSINAMAVNNNLLYVGGKFTGPKTKDLAIFNLTNKEALLLPQLAAKDGSVTYVNTIRHVPSQEMIVVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MUU9</accession>
    <name>A0A1C7MUU9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_11310</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001897">
        <property type="protein sequence ID" value="OBZ80641.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MUU9"/>
    <dbReference type="InParanoid" id="A0A1C7MUU9"/>
    <dbReference type="OrthoDB" id="2296942at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="285"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ80641.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="285" mass="32824" checksum="9F5A8669C4CC00A8" modified="2016-11-30" version="1" fragment="single">MDSTKADLLLKNYFDLCLSDDIEPTFAHFIQTSFQSIRPLLISDHVDNFSDWLSSFKRYAQKNGFSKIKKGPALKAWETYVVFKEPRSIKRSHNTANVVEVLESFKLRKQKENCFVFEEYDVGKAMNDFAQQSMISFIKEHNNASRFRDDMNKWLAIHSIIKLNKHVDADLIDVYKSTKVEGLCKSFKKKFVGKPACLSSSIKVEILDLLTEFQDDEDFKKLKSELCKIVCREDGAVSRTIESLSVLVNKMTSKKKDIGEKKTENILEAVWGCIFKVTKDHDPHG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MVH7</accession>
    <name>A0A1C7MVH7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">V-type proton ATPase subunit E 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">ATP6V1E1</name>
        <name evidence="5" type="ORF">A0J61_11141</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the V-ATPase E subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001709">
        <property type="protein sequence ID" value="OBZ80810.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MVH7"/>
    <dbReference type="FunCoup" id="A0A1C7MVH7">
        <property type="interactions" value="299"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7MVH7"/>
    <dbReference type="InParanoid" id="A0A1C7MVH7"/>
    <dbReference type="OrthoDB" id="10263003at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000329">
        <property type="term" value="C:fungal-type vacuole membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045121">
        <property type="term" value="C:membrane raft"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000221">
        <property type="term" value="C:vacuolar proton-transporting V-type ATPase, V1 domain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046961">
        <property type="term" value="F:proton-transporting ATPase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.1620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2320.30">
        <property type="entry name" value="ATP synthase, E subunit, C-terminal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00311">
        <property type="entry name" value="ATP_synth_E_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038495">
        <property type="entry name" value="ATPase_E_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002842">
        <property type="entry name" value="ATPase_V1_Esu"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45715">
        <property type="entry name" value="ATPASE H+-TRANSPORTING V1 SUBUNIT E1A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01991">
        <property type="entry name" value="vATP-synt_E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160527">
        <property type="entry name" value="V-type ATPase subunit E-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0406">Ion transport</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="140"/>
            <end position="167"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005901"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OBZ80810.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="231" mass="26390" checksum="D254EF7552F06FF4" modified="2016-11-30" version="1">MSSSTARPLNDDEVFNEMKKMVAFIKQEAVEKAREIKVKADEEFNIEKAKIVRQESLNIESVFERKIKQAEVQKKIAQSNHINKTRLRILQERQKVLDDLFEEAEKRIADVSSDEEQYGTLLEGLILQGIYSLMENEVAIRCREQDVDQVNAAIERATEKYEETMKARPSFTVSEDYLPSSSAGGIILSGLYGKITIDNTLNARLDIAKEEMLPQIRVALFGHSPSRTFFN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MVQ7</accession>
    <name>A0A1C7MVQ7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">A0J61_11010</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001586">
        <property type="protein sequence ID" value="OBZ80941.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MVQ7"/>
    <dbReference type="STRING" id="101091.A0A1C7MVQ7"/>
    <dbReference type="InParanoid" id="A0A1C7MVQ7"/>
    <dbReference type="OrthoDB" id="3269380at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051580">
        <property type="entry name" value="ZnF-Chromatin_assoc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23057">
        <property type="entry name" value="JUXTAPOSED WITH ANOTHER ZINC FINGER PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23057:SF0">
        <property type="entry name" value="JUXTAPOSED WITH ANOTHER ZINC FINGER PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="7">
        <location>
            <begin position="22"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="64"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="64"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="77"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OBZ80941.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="87" mass="9451" checksum="ADC2CD3A252AB430" modified="2016-11-30" version="1" fragment="single">HNQHGHCNLLDEENENSLSKPYQCTIGECGKRYKNLNGLKYHIEHSHMAALNQTLATFGSTLFSSSSVPSSPTSSPMLNSAPISGSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MW12</accession>
    <name>A0A1C7MW12_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Lysophospholipase</fullName>
            <ecNumber evidence="6">3.1.1.5</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">Pla2g4a</name>
        <name evidence="9" type="ORF">A0J61_11003</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>a 1-acyl-sn-glycero-3-phosphocholine + H2O = sn-glycerol 3-phosphocholine + a fatty acid + H(+)</text>
            <dbReference type="Rhea" id="RHEA:15177"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16870"/>
            <dbReference type="ChEBI" id="CHEBI:28868"/>
            <dbReference type="ChEBI" id="CHEBI:58168"/>
            <dbReference type="EC" id="3.1.1.5"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the lysophospholipase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.5" evidence="6"/>
    <dbReference type="EMBL" id="LUGH01001581">
        <property type="protein sequence ID" value="OBZ80948.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MW12"/>
    <dbReference type="STRING" id="101091.A0A1C7MW12"/>
    <dbReference type="InParanoid" id="A0A1C7MW12"/>
    <dbReference type="OrthoDB" id="6121437at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004622">
        <property type="term" value="F:phosphatidylcholine lysophospholipase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004623">
        <property type="term" value="F:phospholipase A2 activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046475">
        <property type="term" value="P:glycerophospholipid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1090.10">
        <property type="entry name" value="Cytosolic phospholipase A2 catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016035">
        <property type="entry name" value="Acyl_Trfase/lysoPLipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002642">
        <property type="entry name" value="LysoPLipase_cat_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10728">
        <property type="entry name" value="CYTOSOLIC PHOSPHOLIPASE A2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10728:SF40">
        <property type="entry name" value="PATATIN FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01735">
        <property type="entry name" value="PLA2_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52151">
        <property type="entry name" value="FabD/lysophospholipase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51210">
        <property type="entry name" value="PLA2C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 5 6" id="KW-0442">Lipid degradation</keyword>
    <keyword evidence="4 5 6" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PLA2c" evidence="8">
        <location>
            <begin position="123"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="369"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="379"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="396"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008780"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022963"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU362103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51210"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OBZ80948.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="396" mass="45829" checksum="7BB80BAA087E1C8E" modified="2016-11-30" version="1" fragment="single">MFRQYRCFHKKAPLLKKLTMNKIPSKNPLWSIPFLKHEENDQQKENALISSLMTNKEWLKHKLESIELPSVNAKMAELYPQFTEQFKQLSEGYGKMWDYLTMEDFRKIVEQLKKEENDPTIHPELTKDGRVREGNTLSEEEQEFIKKRKRLQKEAFARLIDEDPNQIEEQDIPVVGLASSGGGYRAMIGLTGYIDAMKQSGIWDCIMYFSGISGSCWTMALYYNQLTNAEPEKLKHHLEEHVSTHWANISNFMNVLLASPDNSKLLLQGAIQRYAQQKGDISLVDIFGVLMGGTLLTKKPSVSRPPEDREAMEQAIQNDTMEHIDNSKVMHLTGQADYLSKGQEPMPIYCVVRHDISYGKTFEERIQELKHSYQGKHKKEAESERETKDEVDHNKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MW34</accession>
    <name>A0A1C7MW34_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_11285</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001866">
        <property type="protein sequence ID" value="OBZ80666.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MW34"/>
    <dbReference type="InParanoid" id="A0A1C7MW34"/>
    <dbReference type="OrthoDB" id="10566499at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ80666.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="268" mass="31228" checksum="447B22894A994E79" modified="2016-11-30" version="1">MLEIQDVDLRRMAECQRFVVVEDQQKFLSSFSFDRFIYCRFRQNPDRMTKKRTERLRQEIVCFEVFESREPNFRPVQSFEDERIARLIEEINYSYPETGRLQQHHRIDSLEAAVKKFPKENSLALPQDVMTWHKMCCAEEELQLLKEEEIQFVENVETRLFSINLRIQSARPEHLLLLKRRKRQLLLLQRLVYTFLGIPPSAPFSLSYPLSPSVSPSLVALSETSADEISVSEAILNESDGIVDGGEISSNEDNEDNLTPLISALNLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MWZ0</accession>
    <name>A0A1C7MWZ0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_10992</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001570">
        <property type="protein sequence ID" value="OBZ80959.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MWZ0"/>
    <dbReference type="STRING" id="101091.A0A1C7MWZ0"/>
    <dbReference type="InParanoid" id="A0A1C7MWZ0"/>
    <dbReference type="OrthoDB" id="2288877at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46579:SF2">
        <property type="entry name" value="C2H2-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46579">
        <property type="entry name" value="F5/8 TYPE C DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="252"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ80959.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="252" mass="28899" checksum="38CA6A5F1D051E81" modified="2016-11-30" version="1" fragment="single">MINLPAQRKVVGFITYNSINACHKCKKQFDAIIAGDKARDFSNFDVDNWIRRTCEEHKEYAKEWLKTSSEAERKRKEKENGTHWSVLLDLPYFDPIRYVGIDIMHNLLLGLTKKMATIWTNPTTVGRNTVPPMLSPARLKEMQSLLEQKLVLPLGHAGSSIAREIAIGDGFSHFKAEEWATWLLVLSPYQLPQRISKKAYDHHMLLVKASRILLAPSLSLSELDQAHEYMKSFLVGFEAVYPNKFLITANFH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MXF8</accession>
    <name>A0A1C7MXF8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_10447</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001178">
        <property type="protein sequence ID" value="OBZ81502.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MXF8"/>
    <dbReference type="InParanoid" id="A0A1C7MXF8"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="9"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ81502.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="71" mass="8243" checksum="CA70A845E77773F3" modified="2016-11-30" version="1">MKSAYNKAVDNSESKSAYTESQRHSWIESNRHHMKFQAISFTDRTQQSMSHTVKNDVASQMKIHVVNINFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MXH0</accession>
    <name>A0A1C7MXH0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_10441</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001173">
        <property type="protein sequence ID" value="OBZ81510.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MXH0"/>
    <dbReference type="InParanoid" id="A0A1C7MXH0"/>
    <dbReference type="OrthoDB" id="2426083at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ81510.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="303" mass="35371" checksum="713B26F61799CBB9" modified="2016-11-30" version="1">MTGLRDTSSTTPDRTHTNQKDMEKIAHRFYQNLYTTDPTEAFSLDGREQRQWQTLLHGHHISQYYHASAPTAFRYLGFYICYSVPQRRYVENMLLEKIKNQIQAFTARGLSLRGRATIANKLILSRLWFTLRLLSPPKRFFEKLRSMIYTFVWQNKYPRVAFSQLCLDFTRGGVGLLEPSRQHLLLQMKWIFSIFSRLGDGLLTSALKYHLGFLSPVSTLPSLALFEPAFRSHPLCSHTLILPVIFRAFDHLGVQFDIPTLPVGLFLKLPLHRMFRNIPQNHWLHRHSTLLAETFLIVDPIQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MXN6</accession>
    <name>A0A1C7MXN6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">ATP-dependent DNA helicase PIF1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">Pif1_2</name>
        <name evidence="2" type="ORF">A0J61_10402</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001156">
        <property type="protein sequence ID" value="OBZ81548.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7MXN6"/>
    <dbReference type="InParanoid" id="A0A1C7MXN6"/>
    <dbReference type="OrthoDB" id="2281104at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049163">
        <property type="entry name" value="Pif1-like_2B_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051055">
        <property type="entry name" value="PIF1_helicase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47642">
        <property type="entry name" value="ATP-DEPENDENT DNA HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21530">
        <property type="entry name" value="Pif1_2B_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0347">Helicase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA helicase Pif1-like 2B" evidence="1">
        <location>
            <begin position="98"/>
            <end position="129"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF21530"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ81548.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="257" mass="29333" checksum="7CAAB010506EEC8E" modified="2016-11-30" version="1">MEPVRQTEADFIEILNKVRLCYFDESVIKYINSRAVIKSDIPNKSLRLYTTRQRVNAANSKDFDSMSGEPVFFLAHDTYNGGSKNSATRALNETRLLQELKLKIDMPVMLIQNLHVSSGWVNDTIAQVKEIDEENVFLSKEGPDSDELTLWIQRISRSVPGTSYLRSQSPIVPAFASTIHXAQSATIDPVAIYLDDMISHDQLYVAMSRVRKSDNLFFFGSELPLRIKRKYGLNLDAIDIVEYAENRQKRNIEEVVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MYH2</accession>
    <name>A0A1C7MYH2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Virulence protein SSD1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">SSD1_1</name>
        <name evidence="4" type="ORF">A0J61_10088</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the RNR ribonuclease family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001027">
        <property type="protein sequence ID" value="OBZ81863.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="FunCoup" id="A0A1C7MYH2">
        <property type="interactions" value="5"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7MYH2"/>
    <dbReference type="InParanoid" id="A0A1C7MYH2"/>
    <dbReference type="OrthoDB" id="372421at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000932">
        <property type="term" value="C:P-body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000175">
        <property type="term" value="F:3'-5'-RNA exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006402">
        <property type="term" value="P:mRNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.700:FF:000002">
        <property type="entry name" value="Cell wall biogenesis protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.690">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.700">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041505">
        <property type="entry name" value="Dis3_CSD2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041093">
        <property type="entry name" value="Dis3l2-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001900">
        <property type="entry name" value="RNase_II/R"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050180">
        <property type="entry name" value="RNR_Ribonuclease"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23355:SF9">
        <property type="entry name" value="DIS3-LIKE EXONUCLEASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23355">
        <property type="entry name" value="RIBONUCLEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17877">
        <property type="entry name" value="Dis3l2_C_term"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17849">
        <property type="entry name" value="OB_Dis3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00773">
        <property type="entry name" value="RNB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00955">
        <property type="entry name" value="RNB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RNB" evidence="3">
        <location>
            <begin position="636"/>
            <end position="967"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="115"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="211"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="275"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1155"/>
            <end position="1186"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="65"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="235"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="289"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="317"/>
            <end position="330"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005785"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00955"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OBZ81863.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="1240" mass="140140" checksum="F1D2B4F562AE9A50" modified="2016-11-30" version="1">MNNTAFETLEHQTAPESTRGLFDFHNRDSAPVPARRRGSVDPQPSRSRPLSLHQPQDRGGHQRSRSASASDLVFQSNGRRNNFALQTLIEEEDAQKRKKDVDLDSIQDMINTLKNLPPLISNPPNGPQSPMIPNSGANGGGHSSQVTNNKRVSYSNSKMNSDNMDFFFEKRRSSRSSDSLFDSNNTGPIFFHDPFSRDDALAEAEAKLIGTFGQKRKENNTSRRNSFHTGPPPTLTSRRYSESQSFDTKGSSNGLMSRRTSLHTLHESSPGRRIMFNKPLNLTSSNKTEPTDFIDHRRPSTGNHQRRLSRDLEQDWRSTPNSVNNSPTLSSFQIVPFTPTRVNFTRDDANPHQRRPLFIAHLPFSALPPLFRSRQLSRGLLRVNKRNRSDAYVYCEDLDEDIYICGSRDRNRALEGDIVAVRLVDVTGVLREKKEKEEAKLARNGGQAKARLPDEEDENEIIFGGDDHVDVVKPKYCGVVVAILERAQNQVFSGTLTLIRPNNKRAQEEKAAEEARKSIHGKDAIIQKEAPRIVWFKSTDKRVPLIAIPIEQAPADFVDSWEKYNTRLFVGSIKRWPITSLHPFGTLERELGSAYELSTQTKAIFADNNVTHTEFSEAVLSCLPSLPFKLESDPSRRDLRDDTVTFTIDPKGSNVLDDALSIRKIEGGLWEIGVHVCDIGYFIKSHSPLDKEARARAVRVDLIHTHVPMIPEILTEQVTNLIPNESRYTFSVIWKMDTNGSVVDTWFGKTIIRSSAQLTYEDAQKLLDNPTDENPVSQSLSSLYELYKVLHATRKANGLFTQMRDHLEYEFEKDEQKPVTVSLRHKKPTEMMVKEFLFLANKSVAQKISSQFPEQALLRRHAPPSERKINDLVAYAARHFGVTLDIRNAATLEASIESIQDSKLRRIVSIIVLKTFQPPKYFCTGSLDISRYAHYSLNVPLFTHFTAPSRRFADVIVHRQLEAAIAPGEQAFTLXKETIQKLAQHCNIKKEAAMYARSQSSTLFLSMHMHELAQQQQQLTTSEPDSVSDNTSGASVIFREAIVVATFDQYFDVVIPELNLEKRIHLACLPVWRSDYNPHNQSLTMFWRKGVDTSTGKKSEWTLSDEEDEEDIDEEGLLEEMNNNFENPVDELDAGAEEVIVSQLAIRGKESFDNSYANKQDIHPNRSVSTPALMNGRPDPVRSTSRRASVVRARLSDSTAYSTEQGFQTIKALDKIRVVLITELGRTPPVIRILAANPFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MYH7</accession>
    <name>A0A1C7MYH7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_10064</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001019">
        <property type="protein sequence ID" value="OBZ81887.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MYH7"/>
    <dbReference type="InParanoid" id="A0A1C7MYH7"/>
    <dbReference type="OrthoDB" id="2250719at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="52"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="57"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="85"/>
            <end position="97"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ81887.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="457" mass="53072" checksum="0DE5131C916D0598" modified="2016-11-30" version="1">MKDWEEEEEEAVKKMVKILTHRHLWILGEDRPELDAQAFSFLTVELLKSSLKKRKRDEKEKQEELEKEEQQDKEEEQQEKEEQKSASSSTLNASMTTATITTNDNAETVGDNWLLCDYNISGRFDELRTRAMDRYNSNKNTISCLDKLLLNHIMFVSESHTKSTLKFFPERVRSMIFESSKQEVRAIPSLVNEWVSDLNKIIRNGAQKEKKSKTAFKHTDVLQKALKAKAWEFEREAREKEDEELAIYASILSHISKKVMRWSSDKLGETTFIHNKLTDVLDCVFGSLNAAMFHYEMQDKFLSNICLKPDYLLTLRTSDGENLELYTMEAKVPEAHKGDVDFVKTSIMLKYMLDELISRGCSPEEAMVFGTLLRGNQIFQYQMSLRHSGIYMMQEVFVGFLPTSSKEIDRLVSLVPMMMDIMATFDKQAEMLEALPSKRKDHPFQRPTAFKLKIKGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N029</accession>
    <name>A0A1C7N029_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_09572</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000881">
        <property type="protein sequence ID" value="OBZ82381.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N029"/>
    <dbReference type="InParanoid" id="A0A1C7N029"/>
    <dbReference type="OrthoDB" id="2439011at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46579">
        <property type="entry name" value="F5/8 TYPE C DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46579:SF1">
        <property type="entry name" value="F5_8 TYPE C DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ82381.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="234" mass="26561" checksum="9CD48E28D9AA344D" modified="2016-11-30" version="1">MVNELLILLQGVNMKMRKQDGSIVIKRVRACMGMISSDLPATKNLAGSMSFNSKSQDETRRASRAWRNAKTKQARIDLEQRSGVRFTILLKLPYFSYDIIAIEPMHALYLGVVKIALKQMLCPDTFSTLQKILPYIRFHSDATSSILTNRVVKEGFSRVKAAEHKKFITSTAHAALLPPTLQASVYNHLIELVHALRILNSSYIKITDINVTLNHLLNFAKQYEAKQSFPYDYT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N0L2</accession>
    <name>A0A1C7N0L2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_09337</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000827">
        <property type="protein sequence ID" value="OBZ82613.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N0L2"/>
    <dbReference type="InParanoid" id="A0A1C7N0L2"/>
    <dbReference type="OrthoDB" id="2275967at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ82613.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="240" mass="26959" checksum="02122E86234D7245" modified="2016-11-30" version="1">MPTLETMNSNVSEDSASFVESVIAEDNIAALQGKEAECAISRQLITIIANTCKKKPSISHSEMVYNVKLIFPLLYAILDWLEDHPTSPVFVSGEEELLSMSKQLTNIKNNSSRNIYKADGVVRLGDDIEVLLVETIGSFGLDNPVKLSFDNSKAMFDLLAMILSIANKYSCLRMSSFKKLKLLFLQPGSDALRLWTLAYSKNGKYGYKRVAKAIISEDYEERSTCFLEFVSFFLNLKEHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N0W2</accession>
    <name>A0A1C7N0W2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Putative UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase SEC</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">SEC_0</name>
        <name evidence="4" type="ORF">A0J61_09239</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000806">
        <property type="protein sequence ID" value="OBZ82712.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N0W2"/>
    <dbReference type="STRING" id="101091.A0A1C7N0W2"/>
    <dbReference type="InParanoid" id="A0A1C7N0W2"/>
    <dbReference type="OrthoDB" id="1926212at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45641:SF19">
        <property type="entry name" value="NEPHROCYSTIN-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45641">
        <property type="entry name" value="TETRATRICOPEPTIDE REPEAT PROTEIN (AFU_ORTHOLOGUE AFUA_6G03870)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13424">
        <property type="entry name" value="TPR_12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13181">
        <property type="entry name" value="TPR_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50293">
        <property type="entry name" value="TPR_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 3" id="KW-0802">TPR repeat</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="76"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="110"/>
            <end position="143"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OBZ82712.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="190" mass="21476" checksum="07CE0D33D7F2A5F2" modified="2016-11-30" version="1">MAYLLRRMALQRPMARIPMAVLPKVQKKTFFINVPKLDRITDAEEQIKIGSDYMNKGSIDMAMHSYHKSVQIAPSGAGYFNIGVCYFQMGKYKDAIQSFERSLEYTPHSADAHTNIASGYLMLKDTAKAIQHLEQASNFNPSDGEVQYNLGCVYEAVGRLEDAKTRFERADLAGIERAQKALDKLKQKMN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N0W4</accession>
    <name>A0A1C7N0W4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_09676</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000907">
        <property type="protein sequence ID" value="OBZ82269.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N0W4"/>
    <dbReference type="InParanoid" id="A0A1C7N0W4"/>
    <dbReference type="OrthoDB" id="3176171at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000785">
        <property type="term" value="C:chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000793">
        <property type="term" value="C:condensed chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000796">
        <property type="term" value="C:condensin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003682">
        <property type="term" value="F:chromatin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007076">
        <property type="term" value="P:mitotic chromosome condensation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43941">
        <property type="entry name" value="STRUCTURAL MAINTENANCE OF CHROMOSOMES PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43941:SF1">
        <property type="entry name" value="STRUCTURAL MAINTENANCE OF CHROMOSOMES PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="171"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="426"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="97"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="171"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="426"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="438"/>
            <end position="456"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ82269.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="482" mass="54656" checksum="EB60E5C72383F62F" modified="2016-11-30" version="1">MTEQAKVEQTTVWRQKAEKAEEELFLSLKENKHYKDVISILETSLEQTKKQIKRQDSLFKTNSNTSFNNSSFSLVVDNKQDDLTANSEVASNNSFDQQELVERIVQLQEDNNQLVRINDDLESQLVIQRNQSALEVKNLELELMKLAAVNDRLEKEMEQVAPQRKSLSAFNRDSNHFTSPPQTPRISSPPLLLSQNNGSTIHSKIQREISSPSISRLSKSASLRSVSTALMDNNRQHLNDEGRIVSFSSSRSDVAGNQRGSLAGRHSKTYFGSTILPPPTAPPCNPLPPIPSPLPAPPTLSESLVQDNETLLSTSRPNSIENSSFLSLRRQDSIASSTFSEVMSASSITSFDSEKYDRIIRSLQRKAQTAENDVKAHQDVICKLETQLLRSESSMLEVKKQLDKLSREKQAYNLEISNLRTQVSQIQSQQMSSNQESISERQELENKLKQQKELKEKAEKARRILENRMDELMNRKSKFMCF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N0Z0</accession>
    <name>A0A1C7N0Z0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Septin spn3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">spn3_1</name>
        <name evidence="3" type="ORF">A0J61_09144</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000783">
        <property type="protein sequence ID" value="OBZ82805.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N0Z0"/>
    <dbReference type="STRING" id="101091.A0A1C7N0Z0"/>
    <dbReference type="InParanoid" id="A0A1C7N0Z0"/>
    <dbReference type="OrthoDB" id="416553at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030379">
        <property type="entry name" value="G_SEPTIN_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18884">
        <property type="entry name" value="SEPTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00735">
        <property type="entry name" value="Septin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51719">
        <property type="entry name" value="G_SEPTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Septin-type G" evidence="2">
        <location>
            <begin position="19"/>
            <end position="338"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU004560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51719"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ82805.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="352" mass="40757" checksum="AAC038E9669B8676" modified="2016-11-30" version="1">MLYSSDISGAKRTRPKKDAIIYLNVMVVGASGSGKTAFVRTFCETLKDEVIKGSFQESKPMILKGPIESTESLYTVSMEIQKEDERIALTLIDTPGFTSGFTIDHHLSYIAKYIDYQFARTLAEETKIKRDKKIQDPHVHSCLYFIETHQPRAISETDKYILKFLSTRVNVIPVIGKSDTLTTAQLKVLQTAFRNEIMEVFQIPIYGHIDVEGESDNSYQEKSQIEKSMELLQIWIDEDHDEDAQAMMDYIQQIPFRLISYEEDAYSGRPIDVATGKEQTDKGTLGRRFPWAMVECENTKHCDFVCLKQMLLSTHRDMLRIETFERFYEQYRSEKLMNRRLKRQPTDTVGFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N184</accession>
    <name>A0A1C7N184_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">NAD(P)H azoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">azoB_1</name>
        <name evidence="2" type="ORF">A0J61_09109</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000775">
        <property type="protein sequence ID" value="OBZ82843.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N184"/>
    <dbReference type="STRING" id="101091.A0A1C7N184"/>
    <dbReference type="InParanoid" id="A0A1C7N184"/>
    <dbReference type="OrthoDB" id="10254221at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051604">
        <property type="entry name" value="Ergot_Alk_Oxidoreductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016040">
        <property type="entry name" value="NAD(P)-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43162">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43162:SF1">
        <property type="entry name" value="PRESTALK A DIFFERENTIATION PROTEIN A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13460">
        <property type="entry name" value="NAD_binding_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD(P)-binding" evidence="1">
        <location>
            <begin position="42"/>
            <end position="154"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ82843.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="369" mass="42706" checksum="3E72FDF2420CC8EA" modified="2016-11-30" version="1">MLLITSVDEYLGHCITSHLSQFHSLRLQIRALIHKTDATAIPSSVLNFSKKGIDVCAVDYMHANDLSKAFRNIEQMILVINGHEDRVQHCQHLCQAAIRSGVRSIVLLSHIGANSEQHIALHDYGCIETYLVQQQQISRQPSFQWTIIRLDWIQQYFHLWACQVESKRTLELPLAYDTGICPVDISDICHVVTSLLTQKKDQNIILVDLDDKHSTQLYTLTGSEPVTSKDLIQILIDATQYNKMTYKLVRPMDTSFYLRNLGHNIWFDERIKKEKSRIFFDDLDNTCAYRQNILNIPSGNNDDFVECYLLTLIRIADVQIQTFLDYFDWVSKTYGSFPIDDIRHLMTGKEPKSIKQYFVENSNSFKPRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N246</accession>
    <name>A0A1C7N246_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_08769</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000707">
        <property type="protein sequence ID" value="OBZ83183.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N246"/>
    <dbReference type="InParanoid" id="A0A1C7N246"/>
    <dbReference type="OrthoDB" id="2286555at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ83183.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="354" mass="40254" checksum="C6AAD16C18DCC429" modified="2016-11-30" version="1">MKLNDNTYGLLKFASVVLCTFHDMIQRSRTEGQRLANMSLTNAATRSLKLLESHNEEGVVADEAEDENELNDEEATPVVDRLHMLYFKKFKKEPFSTNEKEFLVGVMNKKSCIQEKLFGHASKLLLKRDLDAREEIMLKLTLSGVVNTMEPEGYEILKNIFGQEEITILEDPPNSMHIGLSEVNMEALDRVLKSGGEQMDLEAIEEKILREQLRLRGLKMKNKDSELTCYRHFAKLLDCLFKYTDLMLLDGEPSCIAVKEEMIAGQSLHPCLSVNVLSTTAIRKIDAIVAAQVEEERVEFSANEWKKDNATTTSAIKQQSKNLRSNLSILNQLERKFDVQTKSILAVDFVGKYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N3R1</accession>
    <name>A0A1C7N3R1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">WLM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_08243</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000617">
        <property type="protein sequence ID" value="OBZ83710.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N3R1"/>
    <dbReference type="STRING" id="101091.A0A1C7N3R1"/>
    <dbReference type="InParanoid" id="A0A1C7N3R1"/>
    <dbReference type="OrthoDB" id="49605at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070628">
        <property type="term" value="F:proteasome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013536">
        <property type="entry name" value="WLM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47795:SF1">
        <property type="entry name" value="DNA-DEPENDENT METALLOPROTEASE WSS1 HOMOLOG 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47795">
        <property type="entry name" value="UBIQUITIN AND WLM DOMAIN-CONTAINING METALLOPROTEASE SPCC1442.07C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08325">
        <property type="entry name" value="WLM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51397">
        <property type="entry name" value="WLM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="WLM" evidence="2">
        <location>
            <begin position="1"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="123"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51397"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ83710.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="142" mass="15982" checksum="956EA238B30FB771" modified="2016-11-30" version="1">MANRRWSVGELIELTPFEASILDYNRNAGQLIALRLRTDDLSGFRHYDSIRKVLLHELTHNVLDWTAHGGHRLGQGDFYTPTDDEEEEVGGYVGGIRRLDGGNSEMLTDTPEARRQRLAAAALSRLTKKEEQEMDEGCGSSH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N3Y7</accession>
    <name>A0A1C7N3Y7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Serine/threonine-protein kinase HT1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_08116</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000597">
        <property type="protein sequence ID" value="OBZ83832.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N3Y7"/>
    <dbReference type="STRING" id="101091.A0A1C7N3Y7"/>
    <dbReference type="InParanoid" id="A0A1C7N3Y7"/>
    <dbReference type="OrthoDB" id="4062651at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004672">
        <property type="term" value="F:protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003034">
        <property type="entry name" value="SAP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001245">
        <property type="entry name" value="Ser-Thr/Tyr_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050167">
        <property type="entry name" value="Ser_Thr_protein_kinase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23257">
        <property type="entry name" value="SERINE-THREONINE PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23257:SF958">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE WNK4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07714">
        <property type="entry name" value="PK_Tyr_Ser-Thr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02037">
        <property type="entry name" value="SAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00513">
        <property type="entry name" value="SAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50800">
        <property type="entry name" value="SAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SAP" evidence="2">
        <location>
            <begin position="22"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="1">
        <location>
            <begin position="64"/>
            <end position="349"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50800"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ83832.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="350" mass="40526" checksum="28BFE3D20FF2EF63" modified="2016-11-30" version="1">MLFHTVEKHIDDLLESIAYDQLEAMSLAEIIDLCKERGLPTDGNKSQLMSDLLFWPLPAPSAPQLYSSSLDSQRFFKLFLDDTASYVKYNISLNELIYGNKIGELRLTDVSEFDIAEIKHEIHVLKQLRHENVIRFIGVCTHPNHLSIVTEICTQGDLFDVIRNCPKPSFAQQIMYMYDIALGVSYLHTRSNRPSIIHRDLKSMNILISDENKAKINDFGLARIRPKANILMHTQCGTPNCYSFTYIFHRQAPEFWSTNPSYTEKVDVYACGLIFWEILTWGFYGYPYQNLSEHALYTAVKQHDVRPPMTKLTSLYPRNLLVLIMEMWETDPTLRPSMTHVVERLSTYLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N4G6</accession>
    <name>A0A1C7N4G6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">NmrA-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_08384</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000639">
        <property type="protein sequence ID" value="OBZ83566.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N4G6"/>
    <dbReference type="STRING" id="101091.A0A1C7N4G6"/>
    <dbReference type="InParanoid" id="A0A1C7N4G6"/>
    <dbReference type="OrthoDB" id="10254221at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.25.10">
        <property type="entry name" value="UDP-galactose 4-epimerase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051604">
        <property type="entry name" value="Ergot_Alk_Oxidoreductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008030">
        <property type="entry name" value="NmrA-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43162">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43162:SF1">
        <property type="entry name" value="PRESTALK A DIFFERENTIATION PROTEIN A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05368">
        <property type="entry name" value="NmrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NmrA-like" evidence="1">
        <location>
            <begin position="3"/>
            <end position="283"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF05368"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ83566.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="292" mass="32853" checksum="812C9F720E7DE0C9" modified="2016-11-30" version="1">MTQKPVFIIGGTGNIGTKAVKDLLANNVPLTLFARDPEKAKTLFPDHVDHIRIVRGNYDDLDAIKEGIQGHERLLLLVLDNQRPGEIKGNIAKIAYEAGVKQIVDISTIHMSRKYRAGFIPNGQYVADQAIHNIPNRGYLVSLRPHEFMSNLFWTTRKDMKVFADDRDENEVAPLISPNDIGAMAAVILQEDIQKHGDMSYDMTGDLVTGKQRAAIFSKLFGHDVSYMQVTPVEKYHKLMSTGYFPHAVAIDIVDTFKSGVEEKITPCIEIVLGRKPESLEEYLTSNQHRFY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N4U0</accession>
    <name>A0A1C7N4U0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Transcriptional regulator prz1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">prz1_3</name>
        <name evidence="12" type="ORF">A0J61_07911</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000565">
        <property type="protein sequence ID" value="OBZ84038.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N4U0"/>
    <dbReference type="STRING" id="101091.A0A1C7N4U0"/>
    <dbReference type="InParanoid" id="A0A1C7N4U0"/>
    <dbReference type="OrthoDB" id="8922241at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00167">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000065">
        <property type="entry name" value="B-cell CLL/lymphoma 6, member B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000125">
        <property type="entry name" value="Putative zinc finger protein 143"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000446">
        <property type="entry name" value="Zinc finger protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017930">
        <property type="entry name" value="Myb_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001005">
        <property type="entry name" value="SANT/Myb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050527">
        <property type="entry name" value="Snail/Krueppel_Znf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24388:SF54">
        <property type="entry name" value="PROTEIN ESCARGOT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24388">
        <property type="entry name" value="ZINC FINGER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00249">
        <property type="entry name" value="Myb_DNA-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00717">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51294">
        <property type="entry name" value="HTH_MYB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50090">
        <property type="entry name" value="MYB_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 7" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Myb-like" evidence="9">
        <location>
            <begin position="182"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="domain" description="HTH myb-type" evidence="11">
        <location>
            <begin position="186"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="10">
        <location>
            <begin position="496"/>
            <end position="525"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="10">
        <location>
            <begin position="526"/>
            <end position="553"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="10">
        <location>
            <begin position="554"/>
            <end position="581"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="26"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="115"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="158"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="251"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="360"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="438"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="29"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="253"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="270"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="360"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="439"/>
            <end position="448"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="OBZ84038.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="590" mass="64285" checksum="05A6E5064BA23413" modified="2016-11-30" version="1">MARVHMFKPSLEKQNRDVVLDQQDLPASPSIQKTTIEQSQPLDSTSDATTNNTPSPLIDTNGSTLAAALLHKASNSMDVVGTVAAALSVKPASIGLLNETTQEQLLATLRKEAIQPQQAGTSYETHSSKISQEKNTSTEFMDQAAAATALQLLGLAQQSSDKKTAKPDSSNSISKEQQQQTEQQQKRGAWTREEDDLLLAGIKKFGYGRWKEIATIIPGRKGKQLKQRWDNTLAAKYVDQEWLKNKIRDEGLNASSPASSRTSPVAKAHTSVTPRPSVQHDMTSADWVNFAQKISEKLKEGDQMTLETIISQALLSSIQSVAASVTNTTTANATTVVSNQNVTSPSLSSSSAHTDISHINNDTATTHTTTTTTNHDTNTSTHTPSLNYADAAALLLFPHAFQQKLQQTKVSLTSATSSSVQTNSSSLFIPSSNTITNDTENHVKEDQKGSIALSSPVRKRKRSDPALANTQSAAMSIYASSTPITTTVDNQTQTYYPCLFPGCTKTFARLYNLKSHSRTHTDDRPFVCNVCQVAFSRNHDLKRHGKIHGGDKPYQCTGCNKSFSRLDALKRHKSNQRNKATCINAPIFPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N673</accession>
    <name>A0A1C7N673_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Zinc transporter ZupT</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">zupT</name>
        <name evidence="6" type="ORF">A0J61_09101</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000774">
        <property type="protein sequence ID" value="OBZ82844.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N673"/>
    <dbReference type="STRING" id="101091.A0A1C7N673"/>
    <dbReference type="InParanoid" id="A0A1C7N673"/>
    <dbReference type="OrthoDB" id="262547at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046873">
        <property type="term" value="F:metal ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003689">
        <property type="entry name" value="ZIP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02535">
        <property type="entry name" value="Zip"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="12"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="44"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="79"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="111"/>
            <end position="129"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OBZ82844.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="132" mass="14009" checksum="43D1EEE513C9770D" modified="2016-11-30" version="1">MFISSQASSALGISVGIAMSIHNLTEGFMIALPLYYATRSRTTAFTYAAILGGLSQPIGALIGLFLIKNISQQGEDLLFGIVFGCVSGMMSLITVQSMLPQAIRADTNQSYVVAFFFLGIFLVGLSSILEVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N683</accession>
    <name>A0A1C7N683_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_07404</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000497">
        <property type="protein sequence ID" value="OBZ84547.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N683"/>
    <dbReference type="InParanoid" id="A0A1C7N683"/>
    <dbReference type="OrthoDB" id="2224399at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ84547.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="152" mass="17206" checksum="2C0DE35BAABBD7E8" modified="2016-11-30" version="1">MIDAPLANRLYNLLVSQDTSQSYSTELKPTISKVSNYTYHAYKPLGVSFCFVGNDEKLVLDAIDVYNGRTRDGFVAFHSPDDLPCGLTPTMQAHEIVSMLGEPDRKGGGGQTRLPCWIEYKFDTQRDSGILIQLHGFEWEDREMGWTSFVLY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N6X7</accession>
    <name>A0A1C7N6X7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Protein CREG1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">CREG1</name>
        <name evidence="3" type="ORF">A0J61_07115</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000463">
        <property type="protein sequence ID" value="OBZ84842.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N6X7"/>
    <dbReference type="InParanoid" id="A0A1C7N6X7"/>
    <dbReference type="OrthoDB" id="2138282at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.110.10">
        <property type="entry name" value="Electron Transport, Fmn-binding Protein, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055343">
        <property type="entry name" value="CREG_beta-barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012349">
        <property type="entry name" value="Split_barrel_FMN-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37273:SF1">
        <property type="entry name" value="ADL397C-AP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37273">
        <property type="entry name" value="CHROMOSOME 8, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13883">
        <property type="entry name" value="CREG_beta-barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50475">
        <property type="entry name" value="FMN-binding split barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008889513" evidence="1">
        <location>
            <begin position="20"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="domain" description="CREG-like beta-barrel" evidence="2">
        <location>
            <begin position="25"/>
            <end position="193"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ84842.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="202" mass="23404" checksum="524AF8C4F8C18F0A" modified="2016-11-30" version="1">MAIHSFLFCLFFAFHFVECMMLQSVETAAQLARRVVSDAGRGHIVTLMDASVSSDLSGYPFAIMEYYSDECTKDTGNLLLFMSDLQLSARNMHHNANQMSFTITALKDYNRFYGNQSTPVQQPRFTLFGHVSRVPDSQSETAFECFIKTHPEAKPWNHFHDFRFYEFHVEKIYYVGGFGGLNYIGWIPIELYRKAHLHRQTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N6Y8</accession>
    <name>A0A1C7N6Y8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DUF1748-domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_07032</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000455">
        <property type="protein sequence ID" value="OBZ84915.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N6Y8"/>
    <dbReference type="FunCoup" id="A0A1C7N6Y8">
        <property type="interactions" value="2"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N6Y8"/>
    <dbReference type="InParanoid" id="A0A1C7N6Y8"/>
    <dbReference type="OrthoDB" id="16824at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013726">
        <property type="entry name" value="Mitofissin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28075">
        <property type="entry name" value="CHROMOSOME 16, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28075:SF1">
        <property type="entry name" value="DUF1748-DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08520">
        <property type="entry name" value="Mitofissin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ84915.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="74" mass="8494" checksum="3097DD95EB3AB270" modified="2016-11-30" version="1">MTKLIHYTFDAILITTLLAGIKRSTGLQLATSKIESSTIRSYIDKYLNLGEFIFDMSVAYLNQSSYFTKQHKRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N7X1</accession>
    <name>A0A1C7N7X1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_07237</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000478">
        <property type="protein sequence ID" value="OBZ84716.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N7X1"/>
    <dbReference type="InParanoid" id="A0A1C7N7X1"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="148"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="225"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="27"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="44"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="70"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="85"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="149"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="251"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="270"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="280"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="309"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ84716.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="309" mass="32697" checksum="768EE33141D7A9ED" modified="2016-11-30" version="1" fragment="single">MIKTNSIGIKQKSTKPVTSAKEKQETKSTSNPTISTTIHKSLTKHTTNIATTNRTTKASGQKTTTTLAKESTEAKDRYSTRTEKSPVSQTSSHTSVTTENSKSKKENKRSTTTSGKSYHANKLDEKLIMSNLTFFGFTYAETTAASLTSDKRTSNLLDSPKKTATSDRSAKTATTEHASITDHIVHSSSLLGVNLGLGDDDSLLGAHIGVGGDDSLLGVSVGLGNSKKHTTETDGDSNSSTATTTEDDKSTSTTKHSTKTTSADDDDDDSKSSITRENDTSSTTSQHTAKATLADSDEDDDSLLGISIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N840</accession>
    <name>A0A1C7N840_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 9">Mitochondrial import inner membrane translocase subunit TIM22</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">TIM22</name>
        <name evidence="10" type="ORF">A0J61_07159</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Essential core component of the TIM22 complex, a complex that mediates the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane. In the TIM22 complex, it constitutes the voltage-activated and signal-gated channel. Forms a twin-pore translocase that uses the membrane potential as external driving force in 2 voltage-dependent steps.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Component of the TIM22 complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Mitochondrion inner membrane</location>
            <topology evidence="1 9">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the Tim17/Tim22/Tim23 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000468">
        <property type="protein sequence ID" value="OBZ84789.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N840"/>
    <dbReference type="FunCoup" id="A0A1C7N840">
        <property type="interactions" value="401"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N840"/>
    <dbReference type="InParanoid" id="A0A1C7N840"/>
    <dbReference type="OrthoDB" id="75343at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042721">
        <property type="term" value="C:TIM22 mitochondrial import inner membrane insertion complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030943">
        <property type="term" value="F:mitochondrion targeting sequence binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008320">
        <property type="term" value="F:protein transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005198">
        <property type="term" value="F:structural molecule activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045039">
        <property type="term" value="P:protein insertion into mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039175">
        <property type="entry name" value="TIM22"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14110">
        <property type="entry name" value="MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14110:SF0">
        <property type="entry name" value="MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02466">
        <property type="entry name" value="Tim17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 9" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5 9" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="9" id="KW-0653">Protein transport</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0811">Translocation</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="9" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008444"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00020722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU367038"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OBZ84789.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="163" mass="17334" checksum="FB5594B646361C00" modified="2016-11-30" version="1">MNGPFGGMRGQNNGMSLQEQQTIQLLQGAFESCVVKTAMSGVAGFGMGAAFGLFMSSFEYSGPMTNEELVKQTTRQQLRHVAKDMGTRSYSMAKNFGLVGMIYSGTECCIESYRAKNDLANSVAAGAFTGGLLAAKAGPQAMALGAGGFAMFSLAIDWYMRRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N8L2</accession>
    <name>A0A1C7N8L2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="18">Protein transport protein SEC24</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="18" type="primary">SEC24_2</name>
        <name evidence="18" type="ORF">A0J61_06510</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18 19">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="3">Endoplasmic reticulum membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Golgi apparatus membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the SEC23/SEC24 family. SEC24 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000396">
        <property type="protein sequence ID" value="OBZ85433.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N8L2"/>
    <dbReference type="FunCoup" id="A0A1C7N8L2">
        <property type="interactions" value="441"/>
    </dbReference>
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        <property type="entry name" value="von Willebrand factor, type A domain"/>
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    </dbReference>
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        <property type="entry name" value="SEC24-RELATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13803:SF39">
        <property type="entry name" value="SECRETORY 24AB, ISOFORM A"/>
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    </dbReference>
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    </dbReference>
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    <keyword evidence="10" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="11" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0653">Protein transport</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
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        <location>
            <begin position="233"/>
            <end position="269"/>
        </location>
    </feature>
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            <begin position="305"/>
            <end position="541"/>
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        <location>
            <begin position="551"/>
            <end position="634"/>
        </location>
    </feature>
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        <location>
            <begin position="645"/>
            <end position="744"/>
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    </feature>
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        <location>
            <begin position="771"/>
            <end position="833"/>
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        <location>
            <begin position="1"/>
            <end position="78"/>
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        <location>
            <begin position="104"/>
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            <begin position="7"/>
            <end position="25"/>
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            <begin position="104"/>
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    </evidence>
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            <dbReference type="Pfam" id="PF00626"/>
        </source>
    </evidence>
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            <dbReference type="Pfam" id="PF04810"/>
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            <dbReference type="Pfam" id="PF04811"/>
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            <dbReference type="Pfam" id="PF04815"/>
        </source>
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            <dbReference type="Pfam" id="PF08033"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="OBZ85433.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="916" mass="102032" checksum="0E9D74C300635CAD" modified="2016-11-30" version="1">MNPPYHSQPSMASSPSPTPQQATSPHINSRKAKRHYPTYVQPQDAAYPSPAVTRQASPFPQQQQQQQQQQPYAQQQSYAQQPYVQQPYVQQPYVQQPYVQQPYVQQQPVSTPSYPQPSPQPAYAQSPSFVNQTMHNMANMSLHSQDIPLVGQPPQIEDLQLDITSSPVPSNLTATGSSMAQADSRLKHATVNAFPYSNSMIKKSKIPLALMLQPYLSDPQVQVPVVSDTTVARCSRCKTYINPFVQFSAGALKWKCNMCGMDNDVPQEFDWDVTTQQQTDRYSRYELNYGCVDFVAPADYIMRPPQPPVYVFVIDTSFQAIQTGMIGVVADAILASLDKIPNEDGRTKVAFITADNAIAFYRLMSEEPEILVVGDLSDIYLPRASSDLMVNLVESRKAVEQLLARMKTMHNQGQVASNCLGSALQAARKLLAPTGGKMICFQASLPNVGEGIFKPKATTTTDKGHLNQPMMTPSSSFYKTFAGECTKLQICADMFVFGHPKEADADVTTLNIIPRFTGGQTHFYPAFHATHQADCLRLKQEVMSLLEQQIGLEAVMRTRCSEGIVCHAFYGNCTTRVPDIMALPNVPRDQSYCVELVLEDDIQTSHVYFQTALLYTTCFGERRIRVMNICLPVTKSLPELFSSINQVALTRVLCHQAIDKAANGKLRDGRDHLANRSAEIIQSYSKEVLGSPSNAQLSICRSLSLFPLLILSVLKTPAFHDAPVPTDVRTQSAILLRTLPVHSWVHLIHPQFYSIHNMPASAGTQDSNQCVLPPTIHLSSERLEAHGCYLLYDTQNIYLWIGKQAVPPLCKDLLDMPSIQEVQSGQVPMLPQLASPISQKLNAIIQYLQKARQTSYYPTIYIVREDGDPILRSRFLSHLIEDRQPTGPTNAGANQQDVSSGMSYFQWLGYVRAKSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N8M0</accession>
    <name>A0A1C7N8M0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Phosphatidylinositol transfer protein CSR1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">CSR1_0</name>
        <name evidence="3" type="ORF">A0J61_06477</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000392">
        <property type="protein sequence ID" value="OBZ85475.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
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    <dbReference type="OrthoDB" id="43460at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00170">
        <property type="entry name" value="SEC14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.525.10">
        <property type="entry name" value="CRAL-TRIO lipid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001251">
        <property type="entry name" value="CRAL-TRIO_dom"/>
    </dbReference>
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        <property type="entry name" value="CRAL-TRIO_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011074">
        <property type="entry name" value="CRAL/TRIO_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036273">
        <property type="entry name" value="CRAL/TRIO_N_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052432">
        <property type="entry name" value="PITP/CRAL-TRIO"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46590:SF6">
        <property type="entry name" value="CRAL-TRIO DOMAIN-CONTAINING PROTEIN C365.01"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46590">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL TRANSFER PROTEIN CSR1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00650">
        <property type="entry name" value="CRAL_TRIO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03765">
        <property type="entry name" value="CRAL_TRIO_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00180">
        <property type="entry name" value="CRETINALDHBP"/>
    </dbReference>
    <dbReference type="SMART" id="SM01100">
        <property type="entry name" value="CRAL_TRIO_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00516">
        <property type="entry name" value="SEC14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52087">
        <property type="entry name" value="CRAL/TRIO domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46938">
        <property type="entry name" value="CRAL/TRIO N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50191">
        <property type="entry name" value="CRAL_TRIO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CRAL-TRIO" evidence="2">
        <location>
            <begin position="185"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="44"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="45"/>
            <end position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ85475.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="444" mass="49803" checksum="21ABD671CD54081A" modified="2016-11-30" version="1">MSPAAPTDSLSGHVGHLSLKQTETLKQLWAHLFELFNQTGTAYTAPAKQQQPQEEAPSKKSWFSKKDAAPKEVKDVFIGTTTDPAWMDLPLEKALPLIPGSELRFTFWNMVATDNPDAVLLRFLRARKWDLDASYQMLANTLRWRLVMRIDDIVSLGESGMRDELNKLKPELGDCFIKQLNSGKAYLGGPDKMGRGICFINVSLHQKDEQPLEAIKLLTMYVMETSRVIVHQPIESACIVFNMDGFTLKNMDFDFVKFLVGCFEAYYPETLGSCLIHKAPWVFSTVWNLITPLLDPVVASKIHFTKDCKELTNYVDMAALPGIISGEKDKKTLDESVQVAPVPPGTLSKPDTAAYHDYQAMVQKYEAETAEWTKAATTEESSKDYSARHESARQYRVARFRAEMDIRGPTSYQAKGLVTITPEGRVILNFGSDGFAPLDITENV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N8S7</accession>
    <name>A0A1C7N8S7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Serine/threonine-protein kinase mph1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">mph1_0</name>
        <name evidence="9" type="ORF">A0J61_08195</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000609">
        <property type="protein sequence ID" value="OBZ83754.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N8S7"/>
    <dbReference type="FunCoup" id="A0A1C7N8S7">
        <property type="interactions" value="214"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N8S7"/>
    <dbReference type="InParanoid" id="A0A1C7N8S7"/>
    <dbReference type="OrthoDB" id="20524at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000776">
        <property type="term" value="C:kinetochore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004712">
        <property type="term" value="F:protein serine/threonine/tyrosine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007059">
        <property type="term" value="P:chromosome segregation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033316">
        <property type="term" value="P:meiotic spindle assembly checkpoint signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007094">
        <property type="term" value="P:mitotic spindle assembly checkpoint signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034501">
        <property type="term" value="P:protein localization to kinetochore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000131">
        <property type="entry name" value="Dual specificity protein kinase TTK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000224">
        <property type="entry name" value="serine/threonine-protein kinase mph1 isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22974:SF21">
        <property type="entry name" value="DUAL SPECIFICITY PROTEIN KINASE TTK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22974">
        <property type="entry name" value="MIXED LINEAGE PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 9" id="KW-0418">Kinase</keyword>
    <keyword evidence="3 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="8">
        <location>
            <begin position="256"/>
            <end position="532"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="29"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="117"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="179"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="130"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="179"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="199"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="222"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="236"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="285"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OBZ83754.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="535" mass="61089" checksum="697413203F6BE5CC" modified="2016-11-30" version="1">MSKHTESFTSRDSDMSEYDILNASSEILTLLGQDSEDEDDGPPRVSSMEFDPVEFNSQFGKSPLSLKEESIKMDSIQYYVSPIRTNDYQENTYPRNVRRKLSSPNVSSIPAQFNLPISAHNSPVKRSPSIGPSTPFTDSAHSTPPSFNEGLLKREGEQDTMSLERNVSSLHIALESKKYTRSIHDRRSDSSMDHHYDQYSPQKQSPSLKRSTDEFAIPSIKPSLSKQQNAFSQYKKQSEDVPPREGDLMTVNDHHYTIIKEIGRGASGKVYQVFSSEFNEIFALKWVELKKPEDRQNLIEEIELLSSLGTDENIVTLLDHHISPTVILMVMELGEMDLANLLHRQKKKKWDINFIRYFWNQMLKCVDKIHQNQIVHSDLKPANFVLVKGYLKLIDFGIAKRVADDSTRIIRDTQIGTLNYMSPEALMDMNAGRSDAESLMRLGRPSDVWSLGCILYQMVYGHTPFFSLSVPQKIVHIPNRQFKIPFHPTTKSGIDNQTVQVPIILIQLLERCLDRTPALRPTLQELMTHPFVNTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N9A5</accession>
    <name>A0A1C7N9A5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_06281</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000372">
        <property type="protein sequence ID" value="OBZ85667.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N9A5"/>
    <dbReference type="InParanoid" id="A0A1C7N9A5"/>
    <dbReference type="OrthoDB" id="2300186at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ85667.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="156" mass="17288" checksum="B9B8E70C36E384CC" modified="2016-11-30" version="1">MAAAKSSSHKDSLVTLTSSDSSATVSCFLPLSSSCRQDIMNKFAVMNSKNKWCIAENLYLEDIVFKIGQGKQEKKSFSICHSFIVDMNDLCYKTHLTTSQIKNIATRSLSPLPAISAALKKAMDDLKAQSTEDVLGSALNQLKNNKNNEEIYTFFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NA22</accession>
    <name>A0A1C7NA22_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_06005</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000343">
        <property type="protein sequence ID" value="OBZ85937.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NA22"/>
    <dbReference type="InParanoid" id="A0A1C7NA22"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="11"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="56"/>
            <end position="69"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ85937.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="131" mass="14581" checksum="20FF2C91E37ECC17" modified="2016-11-30" version="1">MNSSIEEDYLDCSLPPLSPSSFDSSQFDFDSPKTQSHQVPDILDHQQTLPPVPPNITLTPKSEPVSSPSDLLPLYQASQKTTGSTIEKTREDLMSDIERTIMQMMHSITVGEPIQLSLVSRKQNTGQPLRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NAJ4</accession>
    <name>A0A1C7NAJ4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">ATP-dependent DNA helicase</fullName>
            <ecNumber evidence="1">5.6.2.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_06235</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="5.6.2.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the helicase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.6.2.3" evidence="1"/>
    <dbReference type="EMBL" id="LUGH01000367">
        <property type="protein sequence ID" value="OBZ85719.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NAJ4"/>
    <dbReference type="InParanoid" id="A0A1C7NAJ4"/>
    <dbReference type="OrthoDB" id="2286272at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043139">
        <property type="term" value="F:5'-3' DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000723">
        <property type="term" value="P:telomere maintenance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010285">
        <property type="entry name" value="DNA_helicase_pif1-like_DEAD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10492">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10492:SF57">
        <property type="entry name" value="ATP-DEPENDENT DNA HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05970">
        <property type="entry name" value="PIF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0227">DNA damage</keyword>
    <keyword evidence="1" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="1" id="KW-0234">DNA repair</keyword>
    <keyword evidence="1" id="KW-0347">Helicase</keyword>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA helicase Pif1-like DEAD-box helicase" evidence="2">
        <location>
            <begin position="32"/>
            <end position="185"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU363044"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF05970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ85719.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="201" mass="22111" checksum="48D4E174D54C6E13" modified="2016-11-30" version="1">MDSNGDGLSLLTRTHIQLPLSAEAQPDPSSLQFNDDQKIAYDTIRTEIVNDSARVLSASKLYFIDAPGGSGKXFLFNSLLNSTRRVGDIAIAVASSGIAALLLEGVRTPHSTFKIPIDINTESMCNIKPKSELGNLIKKAKLIVWDEASMTSRTIFEAVDRTFKDIMKDEDPVLQTVPFGVKLNVFWRRFPSGFACHPQGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NAK6</accession>
    <name>A0A1C7NAK6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Metacaspase-1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">MCA1_1</name>
        <name evidence="5" type="ORF">A0J61_05950</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase C14B family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000338">
        <property type="protein sequence ID" value="OBZ85998.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NAK6"/>
    <dbReference type="FunCoup" id="A0A1C7NAK6">
        <property type="interactions" value="442"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NAK6"/>
    <dbReference type="InParanoid" id="A0A1C7NAK6"/>
    <dbReference type="OrthoDB" id="3223806at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004197">
        <property type="term" value="F:cysteine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007034">
        <property type="term" value="P:vacuolar transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12660">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.1230">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050452">
        <property type="entry name" value="Metacaspase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011600">
        <property type="entry name" value="Pept_C14_caspase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005024">
        <property type="entry name" value="Snf7_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48104:SF30">
        <property type="entry name" value="METACASPASE-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48104">
        <property type="entry name" value="METACASPASE-4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00656">
        <property type="entry name" value="Peptidase_C14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03357">
        <property type="entry name" value="Snf7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase C14 caspase" evidence="4">
        <location>
            <begin position="87"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="554"/>
            <end position="586"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="392"/>
            <end position="430"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009005"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00656"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OBZ85998.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="599" mass="67740" checksum="7C109EE54CC59F4A" modified="2016-11-30" version="1">MSYSESRYPEEQESGGDQYDPVFTQDDLQDPNPTYPQPPFLSEHQPSTPVPYGENPEFEKSSLFLHIDPKVKKHGAPPFKLSNCKGKKKALLIGINYFGTKHELSGCINDVANIKEFIQSLYGFSEEDMVILTDDQDHNTKFYPTRENILAAMQWLVTDAQPNDSGHGGRIKDLDGDEEDGFDETIYPVDFEEFEGESGQIPDDLMHDIMVRPLCEGCRLTCIFDSCHSGTALDLPFVYSTKGEIKDQNLFKDAGRGLLSVGLQYISGDHDHAIQSLMDLGRELMSAQDVEARLRERNFSPADVIMFSGCKDNQTSADAKEDGKATGAMSHAFITTLRENPNQSYRALLNNIREILADHYSQRPQMSASHPIDVDLQFEFLFGKRKTPAELLRQHQRAITKAQRELDREREKLERQEKKLIADIKKSAKANQMGACKVMAKDLVRTRRNVQKFYQMKTQLQAVGLRIQTLRSSQQMAEAMKGATKAMGSMNRQMNLPQIQKIMMDFERESEMMDMKDEMMGDAIDDAFEQDEDEEESDEIVNKVLDDIGISFNQELGETPSGLKMPESSVPSERIAQPEGGLSVDDAALQARLDNLRRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NAN7</accession>
    <name>A0A1C7NAN7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF8032 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_06180</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000361">
        <property type="protein sequence ID" value="OBZ85769.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NAN7"/>
    <dbReference type="STRING" id="101091.A0A1C7NAN7"/>
    <dbReference type="InParanoid" id="A0A1C7NAN7"/>
    <dbReference type="OrthoDB" id="5599902at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058345">
        <property type="entry name" value="DUF8032"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22949:SF0">
        <property type="entry name" value="RE27538P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22949">
        <property type="entry name" value="WHITE COLLAR 2 PROTEIN WC2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26087">
        <property type="entry name" value="DUF8032"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF8032" evidence="2">
        <location>
            <begin position="201"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="domain" description="DUF8032" evidence="2">
        <location>
            <begin position="350"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="118"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="309"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="448"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="508"/>
            <end position="532"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="118"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="142"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="160"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="178"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="509"/>
            <end position="524"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF26087"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ85769.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="729" mass="81394" checksum="65A5B10A5D84C28F" modified="2016-11-30" version="1">MATSVTTSTDDIMTLSSATPISETLPHKPGLQLSLQDLLHPTELAENLLESLSNEQLNVIEQAVTKIKQRKLGCSNTQDQDAKNIEQASCHTKSPPYNCQESPNWNPSAVTEIITEPISTSSQDYANNTNDRQLGTGGILQPTLSSLAPSDSQSKEDLIPQQQKTTSNLKSSAKPPATSHTSTSPFLSNHEPTTELKEGVEWVSFVYSHHRTLRRYCIRTDLDKVDIDLLDEEFKKENCVYPRANLPKETYRGNRWSYETECNVLGWKLAYLNLEEIAGKRGLIQRAVDSYRNRYPSMRSRRVARQEKLLKGTLRKRKHRDSTNNNTEEEEHPSKLVKTHHDVHNEKIPKTMLIEDIGSTTKCRIRINIETIALDVIDMTFRKNNCVFPRAIQLTSDMPNLSQRRIDEVKCNEIGWKLCWLNPRQLANKKNLLQRALDLYRNQFAPDIRARKHSPRTPPTFSPPKKEDSIVEKVETNAEDSIQTSNAPRQTIPLTAEALAEQQREFEQLSATTSTSALPAPTTSRRGSTAGQSCYSGTTVTLDFHDYCFSPPPEEDVDMTCEEDTTTTTTTTLHDLSTANSPIFPSVAIFDDLMLATMSSKSMILGSNNLLHDSNESIDSINESINESTGSSYQSTPSPQALLTLSEMYQQAFLMSTASNDSTASAAANELFNANVGSKDDTMFLMTEDTEDSNVIELIARFGTVDAGIGSFTNHTTSMTESSLLSQLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NBE8</accession>
    <name>A0A1C7NBE8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_05588</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000306">
        <property type="protein sequence ID" value="OBZ86361.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NBE8"/>
    <dbReference type="InParanoid" id="A0A1C7NBE8"/>
    <dbReference type="OrthoDB" id="432234at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ86361.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="138" mass="15664" checksum="8E8AE9BBD5B70CCE" modified="2016-11-30" version="1">MTEENICLKKSLPNGDDAIYWIQRISRQVPGTSRTRTQFSIVSAFTTTTTHKAQSATIDYVGKNLDNMLSHGQLYVAMPRAGKTEDLYLFGTEIPLNIKRKFGADVDAVEIQPSVPSQIWHKTITKKQTYYMFKMIGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NBI1</accession>
    <name>A0A1C7NBI1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Endoplasmic reticulum-based factor for assembly of V-ATPase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">A0J61_05637</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000310">
        <property type="protein sequence ID" value="OBZ86318.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NBI1"/>
    <dbReference type="InParanoid" id="A0A1C7NBI1"/>
    <dbReference type="OrthoDB" id="19981at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070072">
        <property type="term" value="P:vacuolar proton-transporting V-type ATPase complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021013">
        <property type="entry name" value="ATPase_Vma12"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31394">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 199"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31394:SF1">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 199"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11712">
        <property type="entry name" value="Vma12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="132"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="164"/>
            <end position="187"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OBZ86318.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="206" mass="23547" checksum="281CFB70935572DB" modified="2016-11-30" version="1">MKFRLTPLIQHHVKDALDHPDLSIVYREEAEKIKMVDLEETSLHPVSMDLVHHLADITDIYFHELILGSGLYFEPKEETPQDPAFLAYMDKLRAEQKEREYKQMVSDVIHSEDQKFNLGIKPSEIKEVKSHIATIFNILFSMCAVYTAVYKASASITSDFGMQVLLSLGGALLIGVVEVLLYANYAYQSTTEKKKKTKRKHTLTTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NBT1</accession>
    <name>A0A1C7NBT1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Protein-lysine N-methyltransferase rrg1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">rrg1</name>
        <name evidence="1" type="ORF">A0J61_05389</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000289">
        <property type="protein sequence ID" value="OBZ86555.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NBT1"/>
    <dbReference type="FunCoup" id="A0A1C7NBT1">
        <property type="interactions" value="35"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NBT1"/>
    <dbReference type="InParanoid" id="A0A1C7NBT1"/>
    <dbReference type="OrthoDB" id="443981at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019410">
        <property type="entry name" value="Methyltransf_16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14614">
        <property type="entry name" value="HEPATOCELLULAR CARCINOMA-ASSOCIATED ANTIGEN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10294">
        <property type="entry name" value="Methyltransf_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ86555.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="338" mass="39024" checksum="812400043B3034B3" modified="2016-11-30" version="1">MSESLLNEVESISSSIRSIGKCSDKTKAYIDQLLDVLDNLIQLSADRFMCLGDYGQDDEYEPYIVHPQDLIRARQYTNTILLKLISAEYLFEDDRDDERMERASRLLAHMSGRGAAGSITRTWHIPYLNSDGVRQELRLPLHEPCYVGNDLGFKTWGAAPMMAKKLLQENIIPHLNDASVLELGTGTGMVGLVCDYLGAAEVHVTDYHPRVLENVAYNIQLNQSHAQVSKLDFIEVALDQSPEWQDRTFDIVIASDLLYEMEHADHLPLAIDRLMKHEFYFMIPLRDTHWEEVTHFEQKMTNLGLVCRKKEDSQHEEEEGMVRFRYYEFIRQPKTIPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NC60</accession>
    <name>A0A1C7NC60_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Rho guanine nucleotide exchange factor scd1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">scd1_1</name>
        <name evidence="5" type="ORF">A0J61_05248</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000279">
        <property type="protein sequence ID" value="OBZ86702.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NC60"/>
    <dbReference type="FunCoup" id="A0A1C7NC60">
        <property type="interactions" value="80"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NC60"/>
    <dbReference type="InParanoid" id="A0A1C7NC60"/>
    <dbReference type="OrthoDB" id="1594986at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000935">
        <property type="term" value="C:division septum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043332">
        <property type="term" value="C:mating projection tip"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005085">
        <property type="term" value="F:guanyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030010">
        <property type="term" value="P:establishment of cell polarity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035556">
        <property type="term" value="P:intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031106">
        <property type="term" value="P:septin ring organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00014">
        <property type="entry name" value="CH_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd05992">
        <property type="entry name" value="PB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00160">
        <property type="entry name" value="RhoGEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.418.10">
        <property type="entry name" value="Calponin-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.900.10">
        <property type="entry name" value="Dbl homology (DH) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010481">
        <property type="entry name" value="Cdc24/Scd1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053026">
        <property type="entry name" value="CDC42_GEF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036872">
        <property type="entry name" value="CH_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035899">
        <property type="entry name" value="DBL_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000219">
        <property type="entry name" value="DH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001331">
        <property type="entry name" value="GDS_CDC24_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053793">
        <property type="entry name" value="PB1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000270">
        <property type="entry name" value="PB1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001849">
        <property type="entry name" value="PH_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47339">
        <property type="entry name" value="CELL DIVISION CONTROL PROTEIN 24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47339:SF1">
        <property type="entry name" value="CELL DIVISION CONTROL PROTEIN 24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06395">
        <property type="entry name" value="CDC24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00564">
        <property type="entry name" value="PB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15411">
        <property type="entry name" value="PH_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00621">
        <property type="entry name" value="RhoGEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00666">
        <property type="entry name" value="PB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00325">
        <property type="entry name" value="RhoGEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54277">
        <property type="entry name" value="CAD &amp; PB1 domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47576">
        <property type="entry name" value="Calponin-homology domain, CH-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48065">
        <property type="entry name" value="DBL homology domain (DH-domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00741">
        <property type="entry name" value="DH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50010">
        <property type="entry name" value="DH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51745">
        <property type="entry name" value="PB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50003">
        <property type="entry name" value="PH_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DH" evidence="3">
        <location>
            <begin position="161"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="domain" description="PH" evidence="2">
        <location>
            <begin position="363"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="domain" description="PB1" evidence="4">
        <location>
            <begin position="741"/>
            <end position="824"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="492"/>
            <end position="532"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="551"/>
            <end position="649"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="667"/>
            <end position="688"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="702"/>
            <end position="738"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="555"/>
            <end position="565"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="611"/>
            <end position="630"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="702"/>
            <end position="737"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51745"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OBZ86702.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="824" mass="93625" checksum="8601021C1860B84B" modified="2016-11-30" version="1">MIDSPIATDSVTNRQASQNASIYYTCRSVLNALQFVPGFEEYMDNESTSGTDTLTKLWHICRQGSSLCYLFNALKPEKPINIPSNSKPKAFIYHFIIACRDQLNFPEETLFTVTDLIQNDTNGFVKVVNTVKRVLDLLEQKEIIEVISQESGNTSDSPKGMRDNVVFELLSTERKYVQDLEVLQNYMREVSAQDILSQNTMHYLFANLNSLVDFQRRFLIQIEEQAANPPQEQRFGLLFIQKEADFSVYEPFCANFQIAQDLVVQESAKLQKLSNIMSPTYELPAMLIKPIQRVCKYPLLIQQLIKATPEDWPYSQENKVGLDAIQRVTKNVNETKRVQENIAVVQDLKKHIVDDSMSNPVVIVETAGNLLLHDKFTLQKHDSDHNREMMVFLFEKMILVCKEIKDVNKNAISIKKKRKEGSLIVRCKIQLTRIEHVKGSSSQNGHYTLHISWMDGELQTILLRCRNDEQLRQWLDVIINLKESTTKVDLISAPQTPRMELSNPLLGYDEDEDSEAEGSNNQNNSDDEEPANSSFFRNRAFSYQHNRLPVEVSSRKASLTPTSSSHIRHFANGMMPPLPRSPTNANYHVPEFNPQLPTSPPTSDPSSPTSLAQATKSGRLNHNIAPSGSLWQRRQQQSLLEEEDEGALESRYEEEMVDPHYHHIVDQKPQSASRPSIHHVRQRSQSSPNIQRHIGQLNQNLVPEVPNTANPYKRTSSSNGYYDSMEPSTPSPQQQAASKDITKVKIHYFGARYAVVVPTDIEFDDLVSRIESKIKANGHEFDTALSLKYQDEDGDLITIGANEDVQMGFETKSSNGTVNLYVSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NC74</accession>
    <name>A0A1C7NC74_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Lipid droplet-associated hydrolase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">A0J61_05246</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Lipid droplet</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the AB hydrolase superfamily. LDAH family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000278">
        <property type="protein sequence ID" value="OBZ86713.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NC74"/>
    <dbReference type="STRING" id="101091.A0A1C7NC74"/>
    <dbReference type="InParanoid" id="A0A1C7NC74"/>
    <dbReference type="OrthoDB" id="448051at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005811">
        <property type="term" value="C:lipid droplet"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016298">
        <property type="term" value="F:lipase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019915">
        <property type="term" value="P:lipid storage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019363">
        <property type="entry name" value="LDAH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13390">
        <property type="entry name" value="LIPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13390:SF0">
        <property type="entry name" value="LIPID DROPLET-ASSOCIATED HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10230">
        <property type="entry name" value="LIDHydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0551">Lipid droplet</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008300"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OBZ86713.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="312" mass="35591" checksum="6E999A2AC973A780" modified="2016-11-30" version="1">MSWIIRNSAIRRPLRTIYEISGYPTETLLWPASATKNKTILMFIPGNPGLVDYYTSFLEGIYTSVASSSLEIIAVSHKGHVVNYNKNEKRKYSLRDQIQHKVDCLDQLAKENGSETNFILMGHSIGAYISVAVLRERPNHGISRIIALFPTLREIAATPNGVQLSRLMSSLPYWIVNVAGSLLFYIPPPLRQCLVQLFTGQSGEGLQVTAHQLLHPTVLQNVLHMGKDEMETVKALDHDFYLDHLDKFIMYYSENDQWAPKDHHEYMTKHFPKGKIHLCTEKIPHAFCLEPKHVDYMAEKAASWIQSDIKKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NC82</accession>
    <name>A0A1C7NC82_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">DNA primase</fullName>
            <ecNumber evidence="10">2.7.7.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">Prim1</name>
        <name evidence="11" type="ORF">A0J61_05232</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 10">Belongs to the eukaryotic-type primase small subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.-" evidence="10"/>
    <dbReference type="EMBL" id="LUGH01000277">
        <property type="protein sequence ID" value="OBZ86722.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NC82"/>
    <dbReference type="FunCoup" id="A0A1C7NC82">
        <property type="interactions" value="95"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NC82"/>
    <dbReference type="InParanoid" id="A0A1C7NC82"/>
    <dbReference type="OrthoDB" id="19606at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005658">
        <property type="term" value="C:alpha DNA polymerase:primase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000785">
        <property type="term" value="C:chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003899">
        <property type="term" value="F:DNA-directed RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006270">
        <property type="term" value="P:DNA replication initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006269">
        <property type="term" value="P:DNA replication, synthesis of primer"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04860">
        <property type="entry name" value="AE_Prim_S"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.920.10:FF:000003">
        <property type="entry name" value="DNA primase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.920.10">
        <property type="entry name" value="DNA primase, PRIM domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002755">
        <property type="entry name" value="DNA_primase_S"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014052">
        <property type="entry name" value="DNA_primase_ssu_euk/arc"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00335">
        <property type="entry name" value="primase_sml"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10536">
        <property type="entry name" value="DNA PRIMASE SMALL SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01896">
        <property type="entry name" value="DNA_primase_S"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56747">
        <property type="entry name" value="Prim-pol domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 10" id="KW-0235">DNA replication</keyword>
    <keyword evidence="2 10" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="3 10" id="KW-0639">Primosome</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0804">Transcription</keyword>
    <keyword evidence="4 10" id="KW-0808">Transferase</keyword>
    <keyword evidence="8" id="KW-0862">Zinc</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009762"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022515"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU003514"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="OBZ86722.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="442" mass="51889" checksum="736F4073A8387CA1" modified="2016-11-30" version="1">MTDASPFEALRDINLDDFFDDPMDTVHQEFAKVNIDSSAQMEQDNPVFLYRLFYHSLFPYKTYFNWLNYDTTPSKIFTHREFSFTLPADIYIRFKSFANVDEFKKELERLQPVKIDIGAVYSIKPKDKKTVSESAFKALEKELVFDIDMTDYDDIRTCCSGGDVCMRCWEFMTVAMKVIDASLREDFGFQHIMWVYSGRRGVHCWVCDERARQLDNESRKAIVKFLDIIKGGNQVHRKVKLPTLLHPSLSRSFKTVEKHFDSIIQKMGILDKPETWKKLLEIVPDLAIQERLDTAWSEQRLTAKEKWEMLVKEAEKADKKKKHYQRDPFPRDIMFQYCYPRLDIKVSTAINHLLKSPFCVHPKTLRVCVPIKIEECDQFNPLAVPNLHTISQELSQTNEKKAKNTSLKPYLDYFEKFVMDMILDVKRAKRGKEKKISLTTGC</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NCA4</accession>
    <name>A0A1C7NCA4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">A0J61_06962</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000446">
        <property type="protein sequence ID" value="OBZ84984.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NCA4"/>
    <dbReference type="FunCoup" id="A0A1C7NCA4">
        <property type="interactions" value="117"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NCA4"/>
    <dbReference type="InParanoid" id="A0A1C7NCA4"/>
    <dbReference type="OrthoDB" id="6770063at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000329">
        <property type="term" value="C:fungal-type vacuole membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000297">
        <property type="term" value="F:spermine transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd17323">
        <property type="entry name" value="MFS_Tpo1_MDR_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000011">
        <property type="entry name" value="MFS multidrug transporter, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23502:SF132">
        <property type="entry name" value="POLYAMINE TRANSPORTER 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="123"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="160"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="191"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="216"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="249"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="280"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="355"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="392"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="433"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="460"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="492"/>
            <end position="514"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="526"/>
            <end position="546"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="8">
        <location>
            <begin position="125"/>
            <end position="552"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="14"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OBZ84984.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="560" mass="62328" checksum="A31ABDBEB31C1E7B" modified="2016-11-30" version="1">MSNLIPSSSSSTLNEKDSYDKDCHGNSKDSKSSIVRDSYAINEPSPDQELEAYREQIREQLPPGVLATKTLSIQPYPSHHTDLEAVASRMLSRHSHKQEVVRYVNWEENDPECPYNWNASFRWAYTIVVAGLVVSAAFGSSVITGHMYGVVDSFGCTQEVAILQVSLMVFGFMIGPLLWSPLSEIYGRKPIYVVALGLYTIFNIPCAVARNIETVLVCRFFSGFFASVALTLAGGSISDLFPTETRGNAIAYFAAAPYAGPVLGPIVGGWINVGTGNWRWIYWVNMIFAGVIWIIICFLPETYHPKLLAERAKKLRKETGDPSYVTVEEEIPISFSEIVQTNLIRPFLMLATEPILLLMSLYVAIIYALLYAFFFAYPIVFGEVHHMNDGEIGLTFIGILIGAAIALLVTPRFESVYLRTIEKRGRPLPEDRLPGMMFAAPWVPISLFIFAWTSFPWCHWIGPTISGIPFGFGMVLLYYAANNYIIDCFPRYVTSALAAKTLVRSGSGAAFPLFINQMYHGLGNQWASTLLAFISLAIVPIPFFFYKWGASIRAKSKSAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NDR8</accession>
    <name>A0A1C7NDR8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">37S ribosomal protein S24, mitochondrial</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">RSM24</name>
        <name evidence="2" type="ORF">A0J61_04710</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000236">
        <property type="protein sequence ID" value="OBZ87237.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NDR8"/>
    <dbReference type="FunCoup" id="A0A1C7NDR8">
        <property type="interactions" value="39"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NDR8"/>
    <dbReference type="InParanoid" id="A0A1C7NDR8"/>
    <dbReference type="OrthoDB" id="283424at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005763">
        <property type="term" value="C:mitochondrial small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032543">
        <property type="term" value="P:mitochondrial translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019349">
        <property type="entry name" value="Ribosomal_mS35_mit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039848">
        <property type="entry name" value="Ribosomal_mS35_mt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13490">
        <property type="entry name" value="MITOCHONDRIAL 28S RIBOSOMAL PROTEIN S28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13490:SF0">
        <property type="entry name" value="SMALL RIBOSOMAL SUBUNIT PROTEIN MS35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10213">
        <property type="entry name" value="MRP-S28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Small ribosomal subunit protein mS35 mitochondrial conserved" evidence="1">
        <location>
            <begin position="87"/>
            <end position="204"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF10213"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ87237.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="243" mass="27842" checksum="BDD63750DFB93D06" modified="2016-11-30" version="1">MLRQTLTKSSTVQVAVRQLSTSSPALAGRQAPRRKAEKKFDVDFMPKFDFDDQTTIGHSIFDNIREVRKYLRKTEFELPKLNAYAKPFEAPKADQILKFKSHTYLGEGHPVERKAVLSVNVDKLELSETEKHKFLLLSGSRYNVNTNELVMSSERFPHRKQNKKFLIDTLNKLIKESKDTKDTFADIPLNLPKPKQRLEFPKEWIRSPSAAPTMTIEESAKVLEQVVEGAKTADPVKVDEKTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NEI5</accession>
    <name>A0A1C7NEI5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_04979</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000256">
        <property type="protein sequence ID" value="OBZ86966.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NEI5"/>
    <dbReference type="InParanoid" id="A0A1C7NEI5"/>
    <dbReference type="OrthoDB" id="2286444at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="74"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="90"/>
            <end position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ86966.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="142" mass="15340" checksum="D13F7A4CED7D1294" modified="2016-11-30" version="1">MPDNLGPPPAPKPVTMPPMTDEDKKKLGMMPAPPPPQMMPMMMSCPPMHTNAIHPAMGPNLVFNFHQSPYGMPAMCTPMPPPGSGGGGGGDKKKEDKKEEKKEEKKDGKKKSVLVQGNPTWNDPRMLAPKGKPIKSNGCMIQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NFK5</accession>
    <name>A0A1C7NFK5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Large ribosomal subunit protein bL21m</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">A0J61_04091</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the bacterial ribosomal protein bL21 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000192">
        <property type="protein sequence ID" value="OBZ87857.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NFK5"/>
    <dbReference type="STRING" id="101091.A0A1C7NFK5"/>
    <dbReference type="InParanoid" id="A0A1C7NFK5"/>
    <dbReference type="OrthoDB" id="5994at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005762">
        <property type="term" value="C:mitochondrial large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01363">
        <property type="entry name" value="Ribosomal_bL21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028909">
        <property type="entry name" value="bL21-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036164">
        <property type="entry name" value="bL21-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001787">
        <property type="entry name" value="Ribosomal_bL21"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00061">
        <property type="entry name" value="L21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21349">
        <property type="entry name" value="50S RIBOSOMAL PROTEIN L21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21349:SF0">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN BL21M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00829">
        <property type="entry name" value="Ribosomal_L21p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141091">
        <property type="entry name" value="L21p-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00044129"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OBZ87857.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="150" mass="17132" checksum="5575DFB670B834BB" modified="2016-11-30" version="1">MFSSLLRGLSAVKGAAFNTNAIRQLQTSTTDSTTLQKLRDQLRYYAVAEISGRPYLITKNDKVIVNRLKDVKVGDVLKLDKVRELGSKDYSLKGSPYVPENIFNINATVIEHTKSKMIQIVKKKRRKNYKRTIEHKQTHTVLRISDVNVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NFU4</accession>
    <name>A0A1C7NFU4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">A0J61_04520</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000223">
        <property type="protein sequence ID" value="OBZ87426.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NFU4"/>
    <dbReference type="InParanoid" id="A0A1C7NFU4"/>
    <dbReference type="OrthoDB" id="6262491at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043130">
        <property type="term" value="F:ubiquitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043161">
        <property type="term" value="P:proteasome-mediated ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010992">
        <property type="term" value="P:ubiquitin recycling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19849:SF1">
        <property type="entry name" value="F-BOX_WD REPEAT-CONTAINING PROTEIN 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19849">
        <property type="entry name" value="PHOSPHOLIPASE A-2-ACTIVATING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="77"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="117"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="157"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="199"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="239"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="279"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="319"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="319"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="344"/>
            <end position="360"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OBZ87426.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="360" mass="40564" checksum="20F75F3C501941C5" modified="2016-11-30" version="1">MVNIGQGAGAFFQTDADIAKQKEKEAKYNYTEGNAIKLSSKALNITLSQDEKYIYIAESGFFVRKISLATSKTVKLFKGHQGPVTCMALGQHHLWTGSWDKTIKQWDLQTGECLHTLQGHTDFIKSLVLVGNQLYSGSSDSFLRRWDTETLTCTFVEKQHKRAIESLAVSQNGQWLYSASSDGTIKRWQLSDMKIDKTYEGHDTSVYCICLSEEDDLWSCSADKTVRRWHTETGQVDMVLTHPDRVKSIALAGPYIVTGSSDDMVRVWSVGSGELVCVIEGHFDEVSSLAITGATLYSGSLDCSLRTWPLTTTAIQQYKETKQKKEQRKKEEEXEQKKNKNGLTEEEERELAELLSDEDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NG76</accession>
    <name>A0A1C7NG76_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">12-oxophytodienoate reductase 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">OPR1_4</name>
        <name evidence="2" type="ORF">A0J61_03980</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000184">
        <property type="protein sequence ID" value="OBZ87980.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NG76"/>
    <dbReference type="FunCoup" id="A0A1C7NG76">
        <property type="interactions" value="288"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NG76"/>
    <dbReference type="InParanoid" id="A0A1C7NG76"/>
    <dbReference type="OrthoDB" id="276546at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02933">
        <property type="entry name" value="OYE_like_FMN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.70:FF:000138">
        <property type="entry name" value="NADPH dehydrogenase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001155">
        <property type="entry name" value="OxRdtase_FMN_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045247">
        <property type="entry name" value="Oye-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22893">
        <property type="entry name" value="NADH OXIDOREDUCTASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22893:SF91">
        <property type="entry name" value="NADPH DEHYDROGENASE 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00724">
        <property type="entry name" value="Oxidored_FMN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51395">
        <property type="entry name" value="FMN-linked oxidoreductases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NADH:flavin oxidoreductase/NADH oxidase N-terminal" evidence="1">
        <location>
            <begin position="8"/>
            <end position="340"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00724"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ87980.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="367" mass="41091" checksum="A8BAB7B1728C5F0F" modified="2016-11-30" version="1">MSKANTALFSPIKVGKNELKHRVVLAPLTRFRANEDGTVTDLQKEYYTQRASEGGLLITEATFITRTAGSYYRAPGIYTKEQVESWKKVTEAVHAKGGVIYLQLWHIGRAALSKLNLGQQPVSSTEKPIPGLNVLGDALEVPRALTPEDIKGIIGDYVQAARNAVEAGFDGVEVHSANGYLLDQFLNSNPNNRTDEYGGTPEKRSRFTYEVVEAVAAAIGAERTGLRLSPWSGFQDVEDDAPYETWGILVKKFQQNIPNLAYIHFIEPKADFCVDHYEKPTETIDPFRKEWKGPFIAGGGYTYYPEEAFKVAEETGSLIAFGRAFIANPDLPERLLNGYPLTKYDRDTFYTNEPKGYTDYPFYNDKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NGF4</accession>
    <name>A0A1C7NGF4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">H/ACA ribonucleoprotein complex subunit NOP10</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Nucleolar protein 10</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">Nucleolar protein family A member 3</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="10">snoRNP protein NOP10</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="primary">nop10</name>
        <name evidence="12" type="ORF">A0J61_04309</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the NOP10 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000208">
        <property type="protein sequence ID" value="OBZ87636.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NGF4"/>
    <dbReference type="FunCoup" id="A0A1C7NGF4">
        <property type="interactions" value="469"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NGF4"/>
    <dbReference type="InParanoid" id="A0A1C7NGF4"/>
    <dbReference type="OrthoDB" id="13807at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031429">
        <property type="term" value="C:box H/ACA snoRNP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030515">
        <property type="term" value="F:snoRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070034">
        <property type="term" value="F:telomerase RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1904874">
        <property type="term" value="P:positive regulation of telomerase RNA localization to Cajal body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031118">
        <property type="term" value="P:rRNA pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031120">
        <property type="term" value="P:snRNA pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="2.20.28.40:FF:000002">
        <property type="entry name" value="H/ACA ribonucleoprotein complex subunit 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.28.40">
        <property type="entry name" value="H/ACA ribonucleoprotein complex, subunit Nop10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007264">
        <property type="entry name" value="H/ACA_rnp_Nop10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036756">
        <property type="entry name" value="H/ACA_rnp_Nop10_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13305:SF0">
        <property type="entry name" value="H_ACA RIBONUCLEOPROTEIN COMPLEX SUBUNIT 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13305">
        <property type="entry name" value="RIBOSOME BIOGENESIS PROTEIN NOP10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04135">
        <property type="entry name" value="Nop10p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144210">
        <property type="entry name" value="Nop10-like SnoRNP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 12" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="5" id="KW-0698">rRNA processing</keyword>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="19"/>
            <end position="40"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00021838"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00030185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00031779"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00032266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="OBZ87636.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="64" mass="7616" checksum="1E0E652A09ED1C14" modified="2016-11-30" version="1">MYLMYYLNDKNERVYTLKKTDPKGMPTKSAHPARFSPDDKFSRQRITIKKRFKILPTQLPARAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NH65</accession>
    <name>A0A1C7NH65_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Synaptobrevin homolog YKT6</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">YKT6</name>
        <name evidence="13" type="ORF">A0J61_03612</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Lipid-anchor</topology>
            <orientation evidence="1">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the synaptobrevin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000158">
        <property type="protein sequence ID" value="OBZ88338.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="FunCoup" id="A0A1C7NH65">
        <property type="interactions" value="923"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NH65"/>
    <dbReference type="InParanoid" id="A0A1C7NH65"/>
    <dbReference type="OrthoDB" id="27923at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000421">
        <property type="term" value="C:autophagosome membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033106">
        <property type="term" value="C:cis-Golgi network membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005768">
        <property type="term" value="C:endosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000329">
        <property type="term" value="C:fungal-type vacuole membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031201">
        <property type="term" value="C:SNARE complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016409">
        <property type="term" value="F:palmitoyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005484">
        <property type="term" value="F:SNAP receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061909">
        <property type="term" value="P:autophagosome-lysosome fusion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006888">
        <property type="term" value="P:endoplasmic reticulum to Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006891">
        <property type="term" value="P:intra-Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042144">
        <property type="term" value="P:vacuole fusion, non-autophagic"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="CDD" id="cd14824">
        <property type="entry name" value="Longin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd15867">
        <property type="entry name" value="R-SNARE_YKT6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.5.110:FF:000020">
        <property type="entry name" value="synaptobrevin homolog YKT6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.50">
        <property type="entry name" value="Longin domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011012">
        <property type="entry name" value="Longin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010908">
        <property type="entry name" value="Longin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045848">
        <property type="entry name" value="R-SNARE_YKT6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001388">
        <property type="entry name" value="Synaptobrevin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042855">
        <property type="entry name" value="V_SNARE_CC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45806">
        <property type="entry name" value="SYNAPTOBREVIN HOMOLOG YKT6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45806:SF1">
        <property type="entry name" value="SYNAPTOBREVIN HOMOLOG YKT6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13774">
        <property type="entry name" value="Longin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00957">
        <property type="entry name" value="Synaptobrevin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00219">
        <property type="entry name" value="SYNAPTOBREVN"/>
    </dbReference>
    <dbReference type="SMART" id="SM01270">
        <property type="entry name" value="Longin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF58038">
        <property type="entry name" value="SNARE fusion complex"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64356">
        <property type="entry name" value="SNARE-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50859">
        <property type="entry name" value="LONGIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00417">
        <property type="entry name" value="SYNAPTOBREVIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50892">
        <property type="entry name" value="V_SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="10" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0488">Methylation</keyword>
    <keyword evidence="6" id="KW-0564">Palmitate</keyword>
    <keyword evidence="8" id="KW-0636">Prenylation</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Longin" evidence="11">
        <location>
            <begin position="7"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="domain" description="V-SNARE coiled-coil homology" evidence="12">
        <location>
            <begin position="136"/>
            <end position="196"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004342"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008025"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023289"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00026133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50859"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="OBZ88338.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="196" mass="22392" checksum="C0D85AF667F76DCA" modified="2016-11-30" version="1">MKLYSILILRKDADKAKILTSQFDLSSFGFFQRGSVQEFMNFSATTIAERTPEGRRQSVESENNVAHVYTHPQGVSGMIISDKDYPSRVAFSLLNKIXDEFLVKFPTNQWKTADSLEYPELAEYLRKYQDPQQADAIMKVQKELDETTAILHKTIDSVLQRGEKLDSLVDRSEALSNQSKMFYKTAKKTNSCCVVM</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NI78</accession>
    <name>A0A1C7NI78_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">Peptide hydrolase</fullName>
            <ecNumber evidence="15">3.4.-.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">A0J61_03109</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18 19">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">May be involved in vacuolar sorting and osmoregulation.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Vacuole membrane</location>
            <topology evidence="3">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 15">Belongs to the peptidase M28 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.-.-" evidence="15"/>
    <dbReference type="EMBL" id="LUGH01000128">
        <property type="protein sequence ID" value="OBZ88842.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NI78"/>
    <dbReference type="FunCoup" id="A0A1C7NI78">
        <property type="interactions" value="19"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NI78"/>
    <dbReference type="InParanoid" id="A0A1C7NI78"/>
    <dbReference type="OrthoDB" id="76293at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005774">
        <property type="term" value="C:vacuolar membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008235">
        <property type="term" value="F:metalloexopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd03875">
        <property type="entry name" value="M28_Fxna_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.10">
        <property type="entry name" value="Zn peptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048024">
        <property type="entry name" value="Fxna-like_M28_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045175">
        <property type="entry name" value="M28_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007484">
        <property type="entry name" value="Peptidase_M28"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12147">
        <property type="entry name" value="METALLOPEPTIDASE M28 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12147:SF58">
        <property type="entry name" value="VACUOLAR MEMBRANE PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04389">
        <property type="entry name" value="Peptidase_M28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53187">
        <property type="entry name" value="Zn-dependent exopeptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="14" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="9 15" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="13 16" id="KW-0472">Membrane</keyword>
    <keyword evidence="8 15" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="6 15 18" id="KW-0645">Protease</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 16" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="11 16" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0926">Vacuole</keyword>
    <keyword evidence="10 15" id="KW-0862">Zinc</keyword>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="28"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="368"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="411"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="443"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="478"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="504"/>
            <end position="521"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="533"/>
            <end position="551"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="571"/>
            <end position="593"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="600"/>
            <end position="619"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M28" evidence="17">
        <location>
            <begin position="143"/>
            <end position="330"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00003273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022554"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="RuleBase" id="RU361240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF04389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="OBZ88842.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="830" mass="92832" checksum="229C08A6B412AEC3" modified="2016-11-30" version="1">MTESVDNERTPLIRRESEVPRTSLKRTYHVYGVTLSFLFLFSLFVHWFRAILPTPLSDIQASKLDDFAGIHAYNEYLSHFEAPHSANTRENGVMKDWIVSVVTGLQQGADHVKIDIIGNDTSADVISHDWFTNNEKWVVDSRNVLVRLHGFAGNQEALLINAHYDSVPTSNGVTDNGMGVVTALETLRYFIAHPPRQTIIFLFNNLEEGGLIGAQSFVKHPWFSSVKLFINLEGAGAGGRAILFRSSNLNAVKKLAYSSASFKHGSPLGNDIFRLKLIKSDTDYTIFTQHGVPGLDLAFYSPRSHYHTPRDDLVHTTPSALQHMGQMVLGAVKSIANSDDLLDTTSEQEPMVLYDILGRFMLAYSFKVYQFLNVLSLLVVPLTSFAVVWYKHQGATEALKQQAMTILYGSAAVFAALIISLVSVGLAAMAMTKINPSMTYGDVYGAALYLFSAAFLGLQLSQFILPAQVQEVLKSTDASWYGLIVFWWMYVVAAFYLATKEIAAFYYAFYLLAFSSLALLIHTHLPADKKFRSPVIFFTQTIVPFILLLEYEYLSMDSMRHATADGTPELAVYVLLSLPILLITLHFIPWLYVAGNQKKALMGSTIAFILLFTICSALQPFNGSWSPNKLLFRQEYTAGNSLATVTLSTATGLAGILKEALPPHEFKTLECNPLSAYLTKCTYQTDMLPKYGSNLTLHEFVHTNPSKHCDQTHCIATTTFSSKHSLMCRVQLDMNTTRIHHLWVNDQEVKSENITSVVTYSNEYEREMRFSVEYPADAPSPKATLGCFYDEWTRSEIPAFTTLRDNLPENALLLIRGQGLAFVNYANITL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NIG3</accession>
    <name>A0A1C7NIG3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Putative ABC transporter ATP-binding protein C16H5.08c</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">A0J61_04827</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000244">
        <property type="protein sequence ID" value="OBZ87134.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NIG3"/>
    <dbReference type="FunCoup" id="A0A1C7NIG3">
        <property type="interactions" value="467"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NIG3"/>
    <dbReference type="InParanoid" id="A0A1C7NIG3"/>
    <dbReference type="OrthoDB" id="2110130at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03221">
        <property type="entry name" value="ABCF_EF-3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000549">
        <property type="entry name" value="ABC transporter ATP-binding protein arb1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000618">
        <property type="entry name" value="ATP-binding cassette (ABC) transporter, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032781">
        <property type="entry name" value="ABC_tran_Xtn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050611">
        <property type="entry name" value="ABCF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19211:SF15">
        <property type="entry name" value="ATP-BINDING CASSETTE SUB-FAMILY F MEMBER 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19211">
        <property type="entry name" value="ATP-BINDING TRANSPORT PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12848">
        <property type="entry name" value="ABC_tran_Xtn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="ABC transporter" evidence="6">
        <location>
            <begin position="69"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="6">
        <location>
            <begin position="382"/>
            <end position="599"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="139"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="302"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="8"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="19"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OBZ87134.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="599" mass="66918" checksum="4A69818B0F5D7F33" modified="2016-11-30" version="1">MSGISASKAKRLAARAAKKGGSAKSSGKNTPAEISESNSAEDLTLENLKIHAERTATGVYTSQERSRDIKIDSYSLNFHGRVLIDNAAIELNFGRRYGLIGANGSGKSTFLQSLAGRDIEIPDHIDIYLLNQEAEPSDMNAVEAVIHSAQKEVARLEKQVEDLLGQEDGADNPLLDDIYERIEGMDPATFETRACTLLAGLGFDAKQMKKMTKDMSGGWRMRVALARALFIKPTLLLLDEPTNHLDLEATVWLEEYLKTYDRILVMVSHSQDFLNGVCTNMMHLTHKRKLIYYGGNYDMFVKTKEENEVNQAKAYAKQQEEIAHIKKFIASAGTYANLVRQAKSKQKIIDKMEAAGLIEKVENPNVFKFSFTDVPKLPPPVLAFQDVSFAYDGNIDHCLYRNLELGIDMDSRVALVGPNGAGKSTLLKLMDNELIPTGGRVQKHTALKLGKYSQHSNDQLDMDLSPIDYMRKKFPEEGSDMEHWRRQLGRYGLTGAHQTSLIRTLSDGLKSRLVFAELAVLRPHIILLDEPTNHLDMESIDSLADAINRFSGGVVLVSHDFRLISQVAKQIWRCENGQVTPFEGTISAYKEQLRKNVKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NIX8</accession>
    <name>A0A1C7NIX8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="18">LETM1 and EF-hand domain-containing protein 1, mitochondrial</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="18" type="primary">LETM1_0</name>
        <name evidence="18" type="ORF">A0J61_02891</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18 19">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000116">
        <property type="protein sequence ID" value="OBZ89063.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NIX8"/>
    <dbReference type="FunCoup" id="A0A1C7NIX8">
        <property type="interactions" value="403"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NIX8"/>
    <dbReference type="InParanoid" id="A0A1C7NIX8"/>
    <dbReference type="OrthoDB" id="275278at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043022">
        <property type="term" value="F:ribosome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030003">
        <property type="term" value="P:intracellular monoatomic cation homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033122">
        <property type="entry name" value="LETM1-like_RBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044202">
        <property type="entry name" value="LETM1/MDM38-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059005">
        <property type="entry name" value="LETM1_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14009">
        <property type="entry name" value="LEUCINE ZIPPER-EF-HAND CONTAINING TRANSMEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14009:SF1">
        <property type="entry name" value="MITOCHONDRIAL PROTON_CALCIUM EXCHANGER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26561">
        <property type="entry name" value="LETM1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07766">
        <property type="entry name" value="LETM1_RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51758">
        <property type="entry name" value="LETM1_RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0106">Calcium</keyword>
    <keyword evidence="3" id="KW-0109">Calcium transport</keyword>
    <keyword evidence="10" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="11" id="KW-0406">Ion transport</keyword>
    <keyword evidence="13 16" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12 14" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="4 16" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 16" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="157"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="domain" description="Letm1 RBD" evidence="17">
        <location>
            <begin position="203"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="453"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="559"/>
            <end position="586"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="15">
        <location>
            <begin position="453"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="15">
        <location>
            <begin position="574"/>
            <end position="586"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022568"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01094"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS51758"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="OBZ89063.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="586" mass="67156" checksum="7DDF7C01C3CFD4BC" modified="2016-11-30" version="1">MYKAIHTSATRQLGLRTNAVAFRHLSRPSPAIRLVLIRPNVASQRGLHLHRELLRSDPKLSKALLNEEKETATSRAAALVKEQQAKAAANAAPSSTAIKPKKTLWQKVKEEAVHYWHGTQLLGLEIRISSKLTWKLLHGGNLTRREHRQLRRTTSDLVRLVPFLFFIVVPFMELLLPVALKLFPNMLPSTYESKSQEEKKKISLLKVRLEMAKFLQETISESGFPGSDHEKAAKEFADFFRKIRITGEQASTEDLLNVARRFEDELTLDNLSRPQLVSMCRYMNINAFGTDNFLRFQIRSRMRQIKADDKAIQQEGIDSLTIQELQNACASRGIRSVGTSPGRLRDELAQWLDLHLNHHVPGTLLILSRAFSYTDRHMTTEEALKATFNSLPDNLVNEAELQVLEQVGASTYKQKLDVLEQQQELIEDESEQEEKEEKARLLAEEEARLAQEKKDLEEAEKKDSFVADEPIVPDEPLKEEPEDAPLSKEQQSELQDALTKLRTKVDVLEERAQLNEIKFQHEDYKELIEELKDATKKEADKATLRMSKKLEKMLETIDKELDDMEKSSSANKETQVEESHKEEKTN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NIZ8</accession>
    <name>A0A1C7NIZ8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Mitochondrial substrate carrier family protein L</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">mcfL</name>
        <name evidence="12" type="ORF">A0J61_04657</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000232">
        <property type="protein sequence ID" value="OBZ87294.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NIZ8"/>
    <dbReference type="STRING" id="101091.A0A1C7NIZ8"/>
    <dbReference type="InParanoid" id="A0A1C7NIZ8"/>
    <dbReference type="OrthoDB" id="193856at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031966">
        <property type="term" value="C:mitochondrial membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000064">
        <property type="term" value="F:L-ornithine transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990575">
        <property type="term" value="P:mitochondrial L-ornithine transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050567">
        <property type="entry name" value="Mitochondrial_Carrier"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45624">
        <property type="entry name" value="MITOCHONDRIAL BASIC AMINO ACIDS TRANSPORTER-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45624:SF57">
        <property type="entry name" value="MITOCHONDRIAL SUBSTRATE CARRIER FAMILY PROTEIN L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 9 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 10" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="139"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="181"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="9">
        <location>
            <begin position="1"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="9">
        <location>
            <begin position="88"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="9">
        <location>
            <begin position="177"/>
            <end position="265"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="OBZ87294.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="273" mass="30771" checksum="B6849921F576851C" modified="2016-11-30" version="1">MASGITKLVVGHPFDTVKIRMQTTSRSDGRFNGPLDCFLKTIRNEGIRGIYKGATPPLVGWMFMDSLMLGTLHNARMLQQSWNGDRPLSLFQHGLAGLAGGLTVSFVATPVEQIKARLQVQYDAKTKVYSGPIDCIRQLVFGLWQGLLPTMLFRSWFFLFWSSYEVFSRELRKRKLSDGTVSFVAGGLSATIFWIGAFPTDVVKNRYMTQPDVHPKKFPTPTAIARYVYRTEGMVGFYRGFLPSFLRAFPTNASAVFMFEFVMRALGNKTESQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NJC9</accession>
    <name>A0A1C7NJC9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 14">Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase</fullName>
            <ecNumber evidence="4 14">4.2.1.134</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="primary">PAS2</name>
        <name evidence="15" type="ORF">A0J61_04542</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="14">Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13 14">
            <text>a very-long-chain (3R)-3-hydroxyacyl-CoA = a very-long-chain (2E)-enoyl-CoA + H2O</text>
            <dbReference type="Rhea" id="RHEA:45812"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:83728"/>
            <dbReference type="ChEBI" id="CHEBI:85440"/>
            <dbReference type="EC" id="4.2.1.134"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 14">Lipid metabolism; fatty acid biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="14">Endoplasmic reticulum membrane</location>
            <topology evidence="14">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 14">Belongs to the very long-chain fatty acids dehydratase HACD family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.134" evidence="4 14"/>
    <dbReference type="EMBL" id="LUGH01000225">
        <property type="protein sequence ID" value="OBZ87404.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NJC9"/>
    <dbReference type="FunCoup" id="A0A1C7NJC9">
        <property type="interactions" value="406"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NJC9"/>
    <dbReference type="InParanoid" id="A0A1C7NJC9"/>
    <dbReference type="OrthoDB" id="46988at2759"/>
    <dbReference type="UniPathway" id="UPA00094"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000324">
        <property type="term" value="C:fungal-type vacuole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102158">
        <property type="term" value="F:very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030497">
        <property type="term" value="P:fatty acid elongation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030148">
        <property type="term" value="P:sphingolipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007034">
        <property type="term" value="P:vacuolar transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042761">
        <property type="term" value="P:very long-chain fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007482">
        <property type="entry name" value="Tyr_Pase-like_PTPLA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11035">
        <property type="entry name" value="VERY-LONG-CHAIN (3R)-3-HYDROXYACYL-COA DEHYDRATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11035:SF3">
        <property type="entry name" value="VERY-LONG-CHAIN (3R)-3-HYDROXYACYL-COA DEHYDRATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04387">
        <property type="entry name" value="PTPLA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="14" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="11 14" id="KW-0275">Fatty acid biosynthesis</keyword>
    <keyword evidence="7 14" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="5 14" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="9 14" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="12 14" id="KW-0456">Lyase</keyword>
    <keyword evidence="10 14" id="KW-0472">Membrane</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 14" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 14" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="24"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="65"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="154"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="185"/>
            <end position="210"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007811"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00036671"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU363109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="OBZ87404.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="226" mass="26100" checksum="EF7B1CDA0DA5F76E" modified="2016-11-30" version="1">MSKPETERATLPPPPPGPKNMKEWYLLSYNQVSFGGWGWILLLTITQLYNTEGDYTKVFDVVWPALSYVQTAALFEVLHSLLGWVRAPVMTTAMQVASRLFLVWGVNYIVPEIHTHWSFTTMIIAWSIAELVRYSFYTFHLSGGIPGFVSWARYNFFFVLYPLGVFSEMMMVYQALPYAKAIDPLYYYGLIAVALIYIPGFPVLFSHMLVQRKKYMRGDTKKSKKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NJH6</accession>
    <name>A0A1C7NJH6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Transcription factor zip1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">zip1</name>
        <name evidence="8" type="ORF">A0J61_02679</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000104">
        <property type="protein sequence ID" value="OBZ89261.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NJH6"/>
    <dbReference type="STRING" id="101091.A0A1C7NJH6"/>
    <dbReference type="InParanoid" id="A0A1C7NJH6"/>
    <dbReference type="OrthoDB" id="1939598at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001228">
        <property type="term" value="F:DNA-binding transcription activator activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000977">
        <property type="term" value="F:RNA polymerase II transcription regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd14705">
        <property type="entry name" value="bZIP_Zip1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.170">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004827">
        <property type="entry name" value="bZIP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046347">
        <property type="entry name" value="bZIP_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13044">
        <property type="entry name" value="ACTIVATING TRANSCRIPTION FACTOR ATF 4/5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13044:SF14">
        <property type="entry name" value="CRYPTOCEPHAL, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07716">
        <property type="entry name" value="bZIP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57959">
        <property type="entry name" value="Leucine zipper domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50217">
        <property type="entry name" value="BZIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00036">
        <property type="entry name" value="BZIP_BASIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="BZIP" evidence="7">
        <location>
            <begin position="100"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="89"/>
            <end position="159"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OBZ89261.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="171" mass="19559" checksum="E09808DDA588F332" modified="2016-11-30" version="1">MSYISSLNLLGDDSPIPLSEESLNEELTLWANAQFTFDTEPGTATNDNFKTQLLHTLNELVNPPNENRSTMTDHLDLMHTSPPIAPIINEKKRKEIDESTEAIEDKRRRNTAASARFRMKKKLKEQALERTAKEMTDKAEALEKRVLELEKEAKWLRALVVEKDPALLEKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NJI4</accession>
    <name>A0A1C7NJI4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Pumilio homology domain family member 3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">Pum2</name>
        <name evidence="11" type="ORF">A0J61_02681</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the PUF3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000104">
        <property type="protein sequence ID" value="OBZ89273.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NJI4"/>
    <dbReference type="STRING" id="101091.A0A1C7NJI4"/>
    <dbReference type="InParanoid" id="A0A1C7NJI4"/>
    <dbReference type="OrthoDB" id="668540at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003730">
        <property type="term" value="F:mRNA 3'-UTR binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000288">
        <property type="term" value="P:nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07920">
        <property type="entry name" value="Pumilio"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.10.10:FF:000004">
        <property type="entry name" value="Pumilio homolog 1 isoform 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033133">
        <property type="entry name" value="PUM-HD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033712">
        <property type="entry name" value="Pumilio_RNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001313">
        <property type="entry name" value="Pumilio_RNA-bd_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12537:SF12">
        <property type="entry name" value="MATERNAL PROTEIN PUMILIO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12537">
        <property type="entry name" value="RNA BINDING PROTEIN PUMILIO-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00806">
        <property type="entry name" value="PUF"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="SMART" id="SM00025">
        <property type="entry name" value="Pumilio"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50302">
        <property type="entry name" value="PUM"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50303">
        <property type="entry name" value="PUM_HD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="PUM-HD" evidence="10">
        <location>
            <begin position="460"/>
            <end position="800"/>
        </location>
    </feature>
    <feature type="repeat" description="Pumilio" evidence="7">
        <location>
            <begin position="480"/>
            <end position="515"/>
        </location>
    </feature>
    <feature type="repeat" description="Pumilio" evidence="7">
        <location>
            <begin position="516"/>
            <end position="551"/>
        </location>
    </feature>
    <feature type="repeat" description="Pumilio" evidence="7">
        <location>
            <begin position="552"/>
            <end position="587"/>
        </location>
    </feature>
    <feature type="repeat" description="Pumilio" evidence="7">
        <location>
            <begin position="588"/>
            <end position="623"/>
        </location>
    </feature>
    <feature type="repeat" description="Pumilio" evidence="7">
        <location>
            <begin position="624"/>
            <end position="659"/>
        </location>
    </feature>
    <feature type="repeat" description="Pumilio" evidence="7">
        <location>
            <begin position="660"/>
            <end position="695"/>
        </location>
    </feature>
    <feature type="repeat" description="Pumilio" evidence="7">
        <location>
            <begin position="696"/>
            <end position="731"/>
        </location>
    </feature>
    <feature type="repeat" description="Pumilio" evidence="7">
        <location>
            <begin position="732"/>
            <end position="774"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="50"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="187"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="385"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="64"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="96"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="202"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="223"/>
            <end position="234"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00060736"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00081811"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="OBZ89273.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="838" mass="96045" checksum="339F38FC540D6F0C" modified="2016-11-30" version="1">MQPNPFSMDFSSSRAQLDLQQPKARNQPQGQLAAMMRGRRDVENELYLDLNERPSSAPPDPRSFQLSLSQANTPGEDHMTLLRNHHTWKPNNQPVSSPLLHDSSSSPRQLWPQQQGRFIQEPSYPTVWTPSHQSATEPPAIDRSASPFQLSNKRTTLNSTSSGSRAIMEENVYQRGYFNVFGRQDEPASNVADQSSSYARFPMSRPMSPPVRSKYVTSPPPRANSTPPTNHHLNAQQQQQRQLEEYEYAQLLMSMNQTNLNDKDDILSKRQRYAQWMQENQLGFDETHSAPWQASDRTNHHRLPHAMWDGQMDKPNKLPHEQQWIQDELVQGRSSPSLMHDFSQPSTPTFSGMMSPDLMSNPNNDRLLLQLQSRQRQILIQQEQILMLKEQMLRQQQQQQQQQQQQNHQQQQQQQLYLPQQQKVPHNINTTGYLQSMSVPTTPSIRHRNIETSEPAVPIIRSALLEEFRNSKNKKFGLKDIINHVVEFSGDQHGSRFIQQKLETATSDDKQFVFDEILPNCLQLMTDVFGNYVIQKLFEHGNQAQKTVLAKQMEGHILSLSLQMYGCRVVQKALEYVLTDQQAALIRELDGCVLKCVKDQNGNHVVQKAIERVPSQHIQFIIDTFYGQVCHLATHPYGCRVIQRMFEFCPEEQTAHLLQELHHSTNQLVQDQYGNYVIQHILEHGHPKDKSLIISKVRGHTLQLSKHKFASNVVEKCVAHGCQEDRQALIDEVLATRPDGTYPLMSMMKDQYANYVVQKMLDVVDGAQRDLLVAKIKPHLQGLKKYTYGKHLISTCLEVEKQMALNKPMNTQDASSVVVETLNVKPSHSNTSLSNSPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NJL5</accession>
    <name>A0A1C7NJL5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Mannan polymerase II complex anp1 subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">anp1_1</name>
        <name evidence="2" type="ORF">A0J61_02646</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ANP1/MMN9/VAN1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000102">
        <property type="protein sequence ID" value="OBZ89311.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NJL5"/>
    <dbReference type="FunCoup" id="A0A1C7NJL5">
        <property type="interactions" value="19"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NJL5"/>
    <dbReference type="InParanoid" id="A0A1C7NJL5"/>
    <dbReference type="OrthoDB" id="2405412at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000136">
        <property type="term" value="C:mannan polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000009">
        <property type="term" value="F:alpha-1,6-mannosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000032">
        <property type="term" value="P:cell wall mannoprotein biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006487">
        <property type="term" value="P:protein N-linked glycosylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="entry name" value="Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052086">
        <property type="entry name" value="Mannan_Polymerase_Subunit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43083:SF6">
        <property type="entry name" value="MANNAN POLYMERASE COMPLEXES SUBUNIT MNN9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43083">
        <property type="entry name" value="MANNAN POLYMERASE II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03452">
        <property type="entry name" value="Anp1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00037964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ89311.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="365" mass="42345" checksum="78CE61303FF33037" modified="2016-11-30" version="1">MSFIFNSNKSPKKILVISAIIALFFILYLSSLFSFTIQQNDFSCAKLNDNTSHLLPLNIPSLSISATKNSLFTDFNRLSSSPTKAKQKKEKVLVLTPLKDAERYLDRYFELLDRTSYPNHLISIGFLVSDSSDNTLGSLERHIHQLQSRNKWNWQHQPFDSIKIYQKDFDFELPSERRHTYEMQPLRRSIMARSRNWLLSAAMRADISWVAWIDVDVVEYPVSIFEDLMAADGDVVVPNCLLQREDHAFWAYDKNNWQETDESRKIQETLEDDFVLLEGYYEFPTHRYLMVDMPTDVPKDHKVPLDGVGATFTLVKAHVHREGANFPAYTYQHQVETEGFAKMAKSMGFSVYGLPGYIIYHIQND</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NJZ2</accession>
    <name>A0A1C7NJZ2_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Beta-catenin-like protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">CTNNBL1</name>
        <name evidence="8" type="ORF">A0J61_03146</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000130">
        <property type="protein sequence ID" value="OBZ88806.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NJZ2"/>
    <dbReference type="FunCoup" id="A0A1C7NJZ2">
        <property type="interactions" value="768"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NJZ2"/>
    <dbReference type="InParanoid" id="A0A1C7NJZ2"/>
    <dbReference type="OrthoDB" id="1898821at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005681">
        <property type="term" value="C:spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010467">
        <property type="term" value="P:gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.10.10:FF:001136">
        <property type="entry name" value="Beta-catenin-like protein 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039678">
        <property type="entry name" value="CTNNBL1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013180">
        <property type="entry name" value="CTNNBL1_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14978:SF0">
        <property type="entry name" value="BETA-CATENIN-LIKE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14978">
        <property type="entry name" value="BETA-CATENIN-LIKE PROTEIN 1 NUCLEAR ASSOCIATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08216">
        <property type="entry name" value="CTNNBL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01156">
        <property type="entry name" value="DUF1716"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Beta-catenin-like protein 1 N-terminal" evidence="7">
        <location>
            <begin position="75"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="46"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM01156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OBZ88806.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="587" mass="67870" checksum="D79494D0B055D769" modified="2016-11-30" version="1" fragment="single">IPAIPTGRNKRKMPATPDMAFFDKYKSEEAESSSDQPDTKRRMVEEPEEQEEYEPYQDQDADLEDEEGRFFGGGLTAEQSNILDLVDEYDAEETEQLTAANVKSMILKFEKAINKNQEMRVRYPDQFEKFMESETDLDEQIKQLLVLTEAPQMYQEFVHLGSVASLMTLLSHENTDIAIDTIDLINELIDEDVGVGEDVERSEQVQASIKSFVEAMIENELLPLLVQNLDRLNEQEEADRQGVFKIMGIFESLVSLDTQYAEHIALKANVLPWLLKRIQTKQFDANVGYASEILSILLQDNRDIRLKVGELDGIDILLRALSVYRRKDAEIEDESEMVENYFNAMCLLLNEPENKVRFLESEGIELMVLMLKEKTLARIRAVKVLNYALGGEQNREKCIRFVDASGLKALFPLLMGKNNRKLKKSHASAFHESEDEEHITCIILSLLRSLKQSDVQRMRVLLKFTENDYEKVDRLIEMKEQYEQKDYNVKRELTDLKQTLDKEDLEEFEAEEYIRRLDAGLFTLQRVCLLIAALSEEEKGIREKAMMLLKRKAQDMSSVFRIIEEETALLADFVTLRRLAHGEELVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NJZ5</accession>
    <name>A0A1C7NJZ5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Oil body-associated protein 1A</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_02521</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the OBAP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000096">
        <property type="protein sequence ID" value="OBZ89437.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NJZ5"/>
    <dbReference type="STRING" id="101091.A0A1C7NJZ5"/>
    <dbReference type="InParanoid" id="A0A1C7NJZ5"/>
    <dbReference type="OrthoDB" id="1901244at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010686">
        <property type="entry name" value="OBAP-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31360">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31360:SF0">
        <property type="entry name" value="OIL BODY-ASSOCIATED PROTEIN 1B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06884">
        <property type="entry name" value="DUF1264"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="183"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="183"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="206"/>
            <end position="218"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009740"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ89437.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="218" mass="24950" checksum="79774E9777A6FD8E" modified="2016-11-30" version="1">MSSTEMMSKAASVLQSFKPLGNICESFCGIHPYCDNLKRQIVSYHYCAMIDEERRQCLIYDDDGPNAKLIAVEYIISERLFKSLPEEEKKYWHSHKYEVESGLLVMTAKSMVPEALVSTAEKEQLQILANCYGKTWQLWPVDDHNKCSSHIPYGPPQLLMAFTKDGQVEPDLVKDRDAHLGISTEKKRKEREGVVVGNPPLPGADHWQHTEPWQIKKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NK31</accession>
    <name>A0A1C7NK31_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">DNA-directed RNA polymerase II subunit rpb7</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">rpb7_1</name>
        <name evidence="6" type="ORF">A0J61_02455</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the eukaryotic RPB7/RPC8 RNA polymerase subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000093">
        <property type="protein sequence ID" value="OBZ89501.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NK31"/>
    <dbReference type="STRING" id="101091.A0A1C7NK31"/>
    <dbReference type="InParanoid" id="A0A1C7NK31"/>
    <dbReference type="OrthoDB" id="1162399at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000932">
        <property type="term" value="C:P-body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005665">
        <property type="term" value="C:RNA polymerase II, core complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003727">
        <property type="term" value="F:single-stranded RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031369">
        <property type="term" value="F:translation initiation factor binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0060213">
        <property type="term" value="P:positive regulation of nuclear-transcribed mRNA poly(A) tail shortening"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045948">
        <property type="term" value="P:positive regulation of translational initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006367">
        <property type="term" value="P:transcription initiation at RNA polymerase II promoter"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd04329">
        <property type="entry name" value="RNAP_II_Rpb7_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1490.120:FF:000001">
        <property type="entry name" value="DNA-directed RNA polymerase II subunit RPB7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.120">
        <property type="entry name" value="RNA polymerase Rpb7-like, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036898">
        <property type="entry name" value="RNA_pol_Rpb7-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045113">
        <property type="entry name" value="Rpb7-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005576">
        <property type="entry name" value="Rpb7-like_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12709:SF4">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12709">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE II, III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03876">
        <property type="entry name" value="SHS2_Rpb7-N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88798">
        <property type="entry name" value="N-terminal, heterodimerisation domain of RBP7 (RpoE)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <feature type="domain" description="RNA polymerase Rpb7-like N-terminal" evidence="5">
        <location>
            <begin position="9"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009307"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF03876"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OBZ89501.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="98" mass="10811" checksum="70EE75FBE99CCB09" modified="2016-11-30" version="1">MFFLKKLTHTISLHPSYFGPNMQSQIKDKLYADVEGTCTGRYGYVITVLTLDDIGKGKILPGSGLAEFKLSYQAIVFKPYKGEVLDAIVTTVNKASCD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NKF7</accession>
    <name>A0A1C7NKF7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Bacterial low temperature requirement A protein-domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_02490</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000094">
        <property type="protein sequence ID" value="OBZ89470.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NKF7"/>
    <dbReference type="STRING" id="101091.A0A1C7NKF7"/>
    <dbReference type="InParanoid" id="A0A1C7NKF7"/>
    <dbReference type="OrthoDB" id="191995at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010640">
        <property type="entry name" value="Low_temperature_requirement_A"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42101">
        <property type="entry name" value="CHROMOSOME 16, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42101:SF1">
        <property type="entry name" value="LOW TEMPERATURE REQUIREMENT A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06772">
        <property type="entry name" value="LtrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="307"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="367"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="396"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="425"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="455"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="484"/>
            <end position="506"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="522"/>
            <end position="542"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="754"/>
            <end position="773"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="785"/>
            <end position="809"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="815"/>
            <end position="834"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="561"/>
            <end position="652"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="719"/>
            <end position="739"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="561"/>
            <end position="589"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="596"/>
            <end position="645"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ89470.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="835" mass="94313" checksum="531855D5C5AD995C" modified="2016-11-30" version="1">MDSSSNHQLSSASVRRGPTLRGGRFRPPIGRSMRIPKQQTSDDEEESVGLAGAGVYDNEAYEMHEKFETDLDEKPVYHHGEETFGDILTHPQKEYHDHQERIQNFKSKMNRWSVTHQLSGEDHQQERLIGAETQHHGDYALVLHFKQLKGNQKFVLDHDTAEDFCQRLSFTPQEKIQFNGVKDTDGLTDFLYKIKRDFSIKIHHKGDFVHGEPGHHHHHQQHNHPDNHTIEFNDNLYVEFKPKHDFHEDVSVEQTRRPFFQHPEPDLSADIGVEKAASWLELFYDLFFVATLTQFTHSHHIKDWSSLGLYAQWFIITWWGWCASSLYTARFDTDDVVHHIYRLVEMCAVIGMAGSSEYFLYSTGYVYGYIALKSVLAVEYFVVFVVALLTKSKSRLALSFYVGANLISIALWASSLVILETSIHRLLWFFGILIEVLVNVIVRSDKSLSWAASHLAERLGLLSLIVLGENLMGLVSLVSEAGNHLIIVVPNFMAVFIIFGFFFMYFEDFNKEIFLHNKYHQIWVYLHFPLHLCQVAFGISLIDVLKIYKYQMIRDHKLPAEEASSAESSSHGESTHGTGTESTHGTSAEATHGTSTEATHGTNTEATHGTGTEATHGTNTEATHGTETSAAAATESTSESTAASSAHHKAKRAIRMIQSDQKSDYNPIDMAMQIQEEQARYNTQKSSWPTTSDHWTVWCKYMAVSAVMSTVQLISSQESEADHPTAASSQHNHLMRRSGGEGASFTESITQYELIFVYKTFLIFAGLILILNSMIKALNTKISDLYGKIIIGSRVINAIVLWSMCALPFAQLDAIVLLCTLTGSLIFQALVDLLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NKG2</accession>
    <name>A0A1C7NKG2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1 9">Mitogen-activated protein kinase</fullName>
            <ecNumber evidence="1 9">2.7.11.24</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">MKP1_1</name>
        <name evidence="12" type="ORF">A0J61_02325</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.24"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="9">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="activity regulation">
        <text evidence="9">Activated by threonine and tyrosine phosphorylation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.24" evidence="1 9"/>
    <dbReference type="EMBL" id="LUGH01000086">
        <property type="protein sequence ID" value="OBZ89617.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NKG2"/>
    <dbReference type="STRING" id="101091.A0A1C7NKG2"/>
    <dbReference type="InParanoid" id="A0A1C7NKG2"/>
    <dbReference type="OrthoDB" id="192887at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004707">
        <property type="term" value="F:MAP kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd07834">
        <property type="entry name" value="STKc_MAPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000040">
        <property type="entry name" value="Mitogen-activated protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000046">
        <property type="entry name" value="Mitogen-activated protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003527">
        <property type="entry name" value="MAP_kinase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050117">
        <property type="entry name" value="MAPK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24055">
        <property type="entry name" value="MITOGEN-ACTIVATED PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01351">
        <property type="entry name" value="MAPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 9 12" id="KW-0418">Kinase</keyword>
    <keyword evidence="9" id="KW-0460">Magnesium</keyword>
    <keyword evidence="4 7 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 8" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3 9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="11">
        <location>
            <begin position="25"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="370"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="379"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="55"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012411"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU361165"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="OBZ89617.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="490" mass="56017" checksum="510E0D7CB3843EF0" modified="2016-11-30" version="1">MIGQTDFYTIELENGSERFTIQKKYKIIRKIGSGSYGSVCSAVNTDTNEVVAIKKCRHVFDKKLITKRCLREMKLLQHFNGHPRIIDLKAMDIVHPQTFNEVYLIQSCCDTTMADIIHSKLILEPVHYQWFIYQLFSGLKYIHSANVLHRDLKPANILVNENCDLRICDFGMARGFSRSSLGHIESQHMTHYVVTRWYRAPEIMLSHHGYDKSIDMWSVGCIFAELLGRKVLFKGTDYVDQLHKIVGILGLPRDTSFWDSSSSVTEYIRSLRDENGLPPPENPIDFHLLFPNTPPEAIHLLQELLHLDPSKRISASQGLEHPFVAAVRDTSEEVDCPNLFDFESFEPIESEHVLRQCIVEEVMRHKGIQDLDSLHPQHINPSQGSRSSSRKYTGSYISTPSSALAAECNSNAIQLAQQGKDILNDNHHHGFNFLVMDVDRLVGEPEDMSEDDMRMMNSDESDIHVGDRRTLLGPSNADFDALERHLSRDW</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NKH3</accession>
    <name>A0A1C7NKH3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 13">Nucleoside diphosphate kinase</fullName>
            <ecNumber evidence="13">2.7.4.6</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">A0J61_02314</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>a 2'-deoxyribonucleoside 5'-diphosphate + ATP = a 2'-deoxyribonucleoside 5'-triphosphate + ADP</text>
            <dbReference type="Rhea" id="RHEA:44640"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61560"/>
            <dbReference type="ChEBI" id="CHEBI:73316"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.4.6"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 11 12">Belongs to the NDK family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.4.6" evidence="13"/>
    <dbReference type="EMBL" id="LUGH01000085">
        <property type="protein sequence ID" value="OBZ89631.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NKH3"/>
    <dbReference type="STRING" id="101091.A0A1C7NKH3"/>
    <dbReference type="InParanoid" id="A0A1C7NKH3"/>
    <dbReference type="OrthoDB" id="2162449at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004550">
        <property type="term" value="F:nucleoside diphosphate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006241">
        <property type="term" value="P:CTP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006183">
        <property type="term" value="P:GTP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006228">
        <property type="term" value="P:UTP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.141">
        <property type="entry name" value="Nucleoside diphosphate kinase-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034907">
        <property type="entry name" value="NDK-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036850">
        <property type="entry name" value="NDK-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001564">
        <property type="entry name" value="Nucleoside_diP_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023005">
        <property type="entry name" value="Nucleoside_diP_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46161">
        <property type="entry name" value="NUCLEOSIDE DIPHOSPHATE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46161:SF3">
        <property type="entry name" value="NUCLEOSIDE DIPHOSPHATE KINASE DDB_G0292928-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00334">
        <property type="entry name" value="NDK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01243">
        <property type="entry name" value="NUCDPKINASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00562">
        <property type="entry name" value="NDK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54919">
        <property type="entry name" value="Nucleoside diphosphate kinase, NDK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00469">
        <property type="entry name" value="NDPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51374">
        <property type="entry name" value="NDPK_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 13" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7 13 15" id="KW-0418">Kinase</keyword>
    <keyword evidence="9" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-0546">Nucleotide metabolism</keyword>
    <keyword evidence="6 13" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 13" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Nucleoside diphosphate kinase-like" evidence="14">
        <location>
            <begin position="2"/>
            <end position="132"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008142"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00017632"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00706"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU004011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU004013"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="SMART" id="SM00562"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="OBZ89631.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="132" mass="15343" checksum="A498328782FE8246" modified="2016-11-30" version="1">MIVIKPDGMAYQEQITNILQQHKFKVVRDKTLSLSKDQVDQWYYDKHEAQYYPSLVRYLTERGPIRVMQLSRIEAISYLRQLIGPTDPQKARQLVPQSIRALYGTNIQENAVHASDSIDSAQRELQLFFSAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NKT5</accession>
    <name>A0A1C7NKT5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Protein KTI12</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">kti12</name>
        <name evidence="5" type="ORF">A0J61_02529</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="4">Interacts with the elongator complex.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the KTI12 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000096">
        <property type="protein sequence ID" value="OBZ89429.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NKT5"/>
    <dbReference type="FunCoup" id="A0A1C7NKT5">
        <property type="interactions" value="358"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NKT5"/>
    <dbReference type="InParanoid" id="A0A1C7NKT5"/>
    <dbReference type="OrthoDB" id="9972657at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003682">
        <property type="term" value="F:chromatin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002098">
        <property type="term" value="P:tRNA wobble uridine modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000827">
        <property type="entry name" value="KTI12 chromatin-associated homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013641">
        <property type="entry name" value="KTI12/PSTK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12435">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08433">
        <property type="entry name" value="KTI12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00025768"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00063730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OBZ89429.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="281" mass="32268" checksum="9121DC20350A2686" modified="2016-11-30" version="1">MPLITFTGYPSSGKSQRASQLKEYLLKRIEEENKTLRVHVIDDKSLHVTKDAYKDAREEKKARGSLLSAVERTLSRDDIVIADGLNYIKGFRYQLYCIARAIGTPHCVIQTGVPPDMAKQWNEARGEEGYQDTIFDELVTRYEEPDERNRWDAPLFTIIYDDKEMPLDKIWDAVILRKALPPNKSTVSKPVSSTNYVYELDKATLEIINAFVEKQKEFGPGGTPMIVPRSETKVINPPRTVTLSELRRLRKQFVTYNKMNTTLDVDRLGDVFVNYLNSNLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NKW4</accession>
    <name>A0A1C7NKW4_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">N-acetyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_02162</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000078">
        <property type="protein sequence ID" value="OBZ89783.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NKW4"/>
    <dbReference type="STRING" id="101091.A0A1C7NKW4"/>
    <dbReference type="InParanoid" id="A0A1C7NKW4"/>
    <dbReference type="OrthoDB" id="329272at2759"/>
    <dbReference type="UniPathway" id="UPA00113">
        <property type="reaction ID" value="UER00529"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006048">
        <property type="term" value="P:UDP-N-acetylglucosamine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd04301">
        <property type="entry name" value="NAT_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039143">
        <property type="entry name" value="GNPNAT1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13355">
        <property type="entry name" value="GLUCOSAMINE 6-PHOSPHATE N-ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13355:SF22">
        <property type="entry name" value="SLL0786 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="7"/>
            <end position="159"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ89783.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="159" mass="18164" checksum="465FF4680B2F7D84" modified="2016-11-30" version="1">MSKFTHLRIEKLDSNHIEDALKVRIAVFVDEQKYTMEDELDGKDEGSTHWVAYCDKENDDGTIEHHVPVGTIRLIPKPNGLAKLGRLAVLSTARGLHIGQALVKTFIDHCRQHQFKDIILHAQYPRRGFYSKLGFTIDEGAETFLEDGTPHICMHMRNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NKX4</accession>
    <name>A0A1C7NKX4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_02226</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000081">
        <property type="protein sequence ID" value="OBZ89715.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NKX4"/>
    <dbReference type="STRING" id="101091.A0A1C7NKX4"/>
    <dbReference type="InParanoid" id="A0A1C7NKX4"/>
    <dbReference type="OrthoDB" id="5587891at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="44"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="74"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="102"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="136"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="178"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="211"/>
            <end position="233"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ89715.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="348" mass="39449" checksum="A9CE4A42C28BF1EC" modified="2016-11-30" version="1">MDAPPEKEFLLYQEMLKNVVASEVPYTSLNENTMVYFKHTASTVVYMSICLTCSLWQLLTAIELVYRVRKWIHFAVLSETLLSFLVILCSVLNPLTSLNCEIRFWISIVFINLGGCCIQSILLYKAYICYDRARWLIIFGSLINLGYIGLIIVFSTMAKLPTYKDIMGNLEWPALAKLGLDIASNVFLSIAFLMVIYRHYRVFGNSLHKTLLSNGIIFSVGVIASNIVTAILISCRVMGGLSADLYSFDWVITSYLLIKQFNYKQNKSEDSNNRQDQEDEEQDISRTMEQSFTNPRFDFYPTHQTGANACQIDSINSRARSPSRFSSGVLSASTTIKPSDDIQPKIVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NL47</accession>
    <name>A0A1C7NL47_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Isocitrate dehydrogenase [NAD] subunit 2, mitochondrial</fullName>
            <ecNumber evidence="6">1.1.1.41</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13">Isocitric dehydrogenase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="12">NAD(+)-specific ICDH</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="16" type="primary">idh2</name>
        <name evidence="16" type="ORF">A0J61_02731</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>D-threo-isocitrate + NAD(+) = 2-oxoglutarate + CO2 + NADH</text>
            <dbReference type="Rhea" id="RHEA:23632"/>
            <dbReference type="ChEBI" id="CHEBI:15562"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.1.1.41"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="5">Octamer of two non-identical subunits IDH1 and IDH2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the isocitrate and isopropylmalate dehydrogenases family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.41" evidence="6"/>
    <dbReference type="EMBL" id="LUGH01000107">
        <property type="protein sequence ID" value="OBZ89206.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NL47"/>
    <dbReference type="FunCoup" id="A0A1C7NL47">
        <property type="interactions" value="586"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NL47"/>
    <dbReference type="InParanoid" id="A0A1C7NL47"/>
    <dbReference type="OrthoDB" id="10261637at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045242">
        <property type="term" value="C:isocitrate dehydrogenase complex (NAD+)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004449">
        <property type="term" value="F:isocitrate dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006102">
        <property type="term" value="P:isocitrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.718.10:FF:000003">
        <property type="entry name" value="Isocitrate dehydrogenase [NAD] subunit, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.718.10">
        <property type="entry name" value="Isopropylmalate Dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019818">
        <property type="entry name" value="IsoCit/isopropylmalate_DH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004434">
        <property type="entry name" value="Isocitrate_DH_NAD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024084">
        <property type="entry name" value="IsoPropMal-DH-like_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00175">
        <property type="entry name" value="mito_nad_idh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11835">
        <property type="entry name" value="DECARBOXYLATING DEHYDROGENASES-ISOCITRATE, ISOPROPYLMALATE, TARTRATE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11835:SF34">
        <property type="entry name" value="ISOCITRATE DEHYDROGENASE [NAD] SUBUNIT ALPHA, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00180">
        <property type="entry name" value="Iso_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01329">
        <property type="entry name" value="Iso_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53659">
        <property type="entry name" value="Isocitrate/Isopropylmalate dehydrogenase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00470">
        <property type="entry name" value="IDH_IMDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-0520">NAD</keyword>
    <keyword evidence="10" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="Isopropylmalate dehydrogenase-like" evidence="15">
        <location>
            <begin position="49"/>
            <end position="374"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007769"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011567"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00013012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00030631"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00030683"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00072026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="SMART" id="SM01329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="OBZ89206.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="380" mass="40798" checksum="E338F1891A2C0329" modified="2016-11-30" version="1">MFLSRTSSAALKASAWASVKSNSVRAITTATPSITQAFNAQKNSNGNYLVTLIPGDGIGPEISRSVKDIFAAAKTPIEWEEVDVTPIIKDGKTAIPDEAIASVRTSTVALKGPLATPIGKGHVSLNLTLRRTFNLYANVRPCRSVAGYKTPYENVDTVLIRENTEGEYSGIEHEVVDGVVQSIKLITKEASERVARYAFTYAESVGRDRVTAVHKANIMKLADGLFLDACKQVAKEFPNIKFDDVLLDRACLHITADPSLYADTVMVMPNLYGDILSDMSAGLIGGLGLTPSGNIGRDASIFEAVHGTAPDIAGQDKANPTALLLSGIMMLKHMRLTSQAENIEQAVFKTLAEGKYLTADLGGRATNTEYTNAVISNLKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NL79</accession>
    <name>A0A1C7NL79_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Homeobox protein HD-10</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">HD-10_0</name>
        <name evidence="9" type="ORF">A0J61_02080</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 5 6">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000074">
        <property type="protein sequence ID" value="OBZ89877.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NL79"/>
    <dbReference type="STRING" id="101091.A0A1C7NL79"/>
    <dbReference type="InParanoid" id="A0A1C7NL79"/>
    <dbReference type="OrthoDB" id="6159439at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000976">
        <property type="term" value="F:transcription cis-regulatory region binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00086">
        <property type="entry name" value="homeodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001356">
        <property type="entry name" value="HD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017970">
        <property type="entry name" value="Homeobox_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051775">
        <property type="entry name" value="Homeobox_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24323">
        <property type="entry name" value="CEH-10 HOMEODOMAIN-CONTAINING HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24323:SF7">
        <property type="entry name" value="HOMEOBOX DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00046">
        <property type="entry name" value="Homeodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00389">
        <property type="entry name" value="HOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00027">
        <property type="entry name" value="HOMEOBOX_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50071">
        <property type="entry name" value="HOMEOBOX_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 5 6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3 5 6" id="KW-0371">Homeobox</keyword>
    <keyword evidence="4 5 6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Homeobox" evidence="8">
        <location>
            <begin position="63"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="Homeobox" evidence="5">
        <location>
            <begin position="65"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="124"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="124"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="145"/>
            <end position="154"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OBZ89877.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="409" mass="46716" checksum="29FA03199D8FC401" modified="2016-11-30" version="1">MTIVNELQPFEQSFSVTLDDDVHEKEKPSYLSSPNDMTGTSDYLLETFHQYPHGDFRPTFYNPFEIKHRRRTSRTQLKVLEKSFSENSKPNANARRMLAQKLDMTPRGVQIWFQNRRAKAKTLKKKIKHNGCHRQQMKTTKKAEETEEDDYEEDDLSLNEDEFTEMADPRQQPIHCSSYEEECSDGIDAQLEFPCHVSPIDMGSSDPSSILFSQFFSDPLEFNYLYPPPPPSSWLWTNHDNVRTVATKAAAIAAASSYQTTSMPNSVPCWINDSSDKRRRSCPMPVKDMMSTNQIFVNRQTTPILSFSSSPWPPSLKDTHVGAKRSLSFSQQQNLDYYYSKDTNLTYQQEQLSFQLTPPLTASCSASTVAGSPISLDSLYHEPIVQQGNLICPPNANLPHPLIHGFYEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NL99</accession>
    <name>A0A1C7NL99_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">sterol 3beta-glucosyltransferase</fullName>
            <ecNumber evidence="2">2.4.1.173</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">ATG26_0</name>
        <name evidence="7" type="ORF">A0J61_02703</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the glycosyltransferase 28 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.173" evidence="2"/>
    <dbReference type="EMBL" id="LUGH01000105">
        <property type="protein sequence ID" value="OBZ89256.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NL99"/>
    <dbReference type="STRING" id="101091.A0A1C7NL99"/>
    <dbReference type="InParanoid" id="A0A1C7NL99"/>
    <dbReference type="OrthoDB" id="10261837at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016906">
        <property type="term" value="F:sterol 3-beta-glucosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016125">
        <property type="term" value="P:sterol metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd03784">
        <property type="entry name" value="GT1_Gtf-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.2000:FF:000029">
        <property type="entry name" value="Sterol 3-beta-glucosyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2000">
        <property type="entry name" value="Glycogen Phosphorylase B"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010610">
        <property type="entry name" value="EryCIII-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050426">
        <property type="entry name" value="Glycosyltransferase_28"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004276">
        <property type="entry name" value="GlycoTrans_28_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004182">
        <property type="entry name" value="GRAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001849">
        <property type="entry name" value="PH_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002213">
        <property type="entry name" value="UDP_glucos_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48050">
        <property type="entry name" value="STEROL 3-BETA-GLUCOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48050:SF25">
        <property type="entry name" value="STEROL 3-BETA-GLUCOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06722">
        <property type="entry name" value="EryCIII-like_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03033">
        <property type="entry name" value="Glyco_transf_28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02893">
        <property type="entry name" value="GRAM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00169">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00568">
        <property type="entry name" value="GRAM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00233">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53756">
        <property type="entry name" value="UDP-Glycosyltransferase/glycogen phosphorylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50003">
        <property type="entry name" value="PH_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PH" evidence="6">
        <location>
            <begin position="86"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="322"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="415"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="498"/>
            <end position="522"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1062"/>
            <end position="1103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="323"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="378"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="498"/>
            <end position="508"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="1062"/>
            <end position="1073"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="1092"/>
            <end position="1102"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012650"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OBZ89256.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="1233" mass="139145" checksum="B3BA049768264E13" modified="2016-11-30" version="1">MSEISIECDTIQSNDSRSLLLDDHTNYSDRRLLETKVRSAFELPSTEVLNNEFPCYLIRLVTLPGWMYITSNYVCFYASLPGKKKGPYKAGYLSKKNHITSPRTYRYYFELKNHVFSWYASAETKYAPINSIDLKCITKIGPSRHKKHGIRLTTNTNHHYTIIADSELSQREWMDELRRGVFMAQHAGNSVRIVLPFSKITNVDKPLVFQFATSIRIRFQDDLLSDNSVGEEDYYFSFFPDIDKAFHEIVTNWTIKTARLSTTKEERNEPVASQPPANGNSFMSFDSFLDNISTAALPTVLMGKLVNITSLFQVQQRSVATGDAEDALEDKDSTDESEDEPDTKQTERGLTEASPTSSSKSKRSSFFSKSVPDVPESTEVSSLAVSTPSTDGSVVKKRPHSASYSFTKMPWSIKNQVSRTDNNKSSIDSLSGKTAPSSSQQTNATTRSINNSLSSIRQHISPTYLYNKLHTHTASTSPSPDVANTDMTHPSADISLMSHEDSDREKNHLSPTTTRKQRAKSVGSAIFTSTWSKLAPSIIDNYYQQQHINENSHLHPKGPVWLNDSIIEELESFIQPSQYDGSDSESDTDSEGQTMLESLKSTGNDLLKQGQQDTMNEHLNANFPMLLEAEKVNAVFKASFWRTIPYSGKIYITDKFFCFHSRVLAGQQKFIVSWQDVIKVKKIKARNYQLLYGMTMIVKDIADELKMTKEDDFDASSVHSKASNTISLASNIILDRPEHVEPPHDYDGPPLLSSSSIISKPSIKFKKPTKPLHITCLTIGSRGDVQPYLALCKELQKDGHTCRIATHPEYEKWVTDHNVEFRSIGGDPGDLMKLCIDNSFLSVSFIREGTKFFFTWFESLLVSSYEACKGTDVIIESPSAMVGVHMAEKLQVPYFRSMPFPFTRTTKFPHPFATQTAAGGRVFNDMTYVMIDTALWAGTSRYINRFRREVLQLPNTNLDRLELWKVPHLYSFSPTVVHPPKDWPDYIHCTGYWFLDNPDKSWQPHASLTEFLQSKNDNRPIVYIGFGSIIVPDPVETTRMIVDSVLKANVRAIICKGWSSRTSSNVSTGLTKNTSRHKKSRSEADVGNIKQEEDEQEEDSEQMLDQHPGTIYQIDSVPHDWLFPQIQGVVHHGGAGTTAAGLRAGLPTVIKPFFGDQRFWGQRVEELQVGVCLTKLKEAQLTEALKTITQNEAMVIKAQRLGEAIRKENGPRNAVENMYRELEFAKAQRISHS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NLJ9</accession>
    <name>A0A1C7NLJ9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Protein BET1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">Bet1</name>
        <name evidence="11" type="ORF">A0J61_02626</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Endomembrane system</location>
            <topology evidence="8">Single-pass type IV membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Golgi apparatus membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000101">
        <property type="protein sequence ID" value="OBZ89336.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NLJ9"/>
    <dbReference type="FunCoup" id="A0A1C7NLJ9">
        <property type="interactions" value="14"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NLJ9"/>
    <dbReference type="InParanoid" id="A0A1C7NLJ9"/>
    <dbReference type="OrthoDB" id="3063237at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd15853">
        <property type="entry name" value="SNARE_Bet1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039899">
        <property type="entry name" value="BET1_SNARE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000727">
        <property type="entry name" value="T_SNARE_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12791">
        <property type="entry name" value="GOLGI SNARE BET1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF58038">
        <property type="entry name" value="SNARE fusion complex"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50192">
        <property type="entry name" value="T_SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0653">Protein transport</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="82"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="domain" description="T-SNARE coiled-coil homology" evidence="10">
        <location>
            <begin position="11"/>
            <end position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004394"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00046280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="OBZ89336.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="128" mass="14482" checksum="BDF98EC85EF6D919" modified="2016-11-30" version="1">MSTSNAKNNGYIFEQQNDIRLNELSSKLSAIKNITIDIHQDVSDQDRLLDESHNQFSGLGNSLQNSFGRMNRMISKRHQRQLCFYVSIALCVFFVLYYGVPLISYLFGSAESDPTADDILTTPHVGDM</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NLX1</accession>
    <name>A0A1C7NLX1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_01855</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000064">
        <property type="protein sequence ID" value="OBZ90087.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NLX1"/>
    <dbReference type="InParanoid" id="A0A1C7NLX1"/>
    <dbReference type="OrthoDB" id="10597053at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="30"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ90087.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="82" mass="9538" checksum="18E1FE3BD046CA45" modified="2016-11-30" version="1">MAGVVFLHAMRSETDYMQANAFSEKKRHIEAKLQLKSDILELEMEKLKHEQELLRVQEKLLVESKKIIALLEQMLVAQEAES</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NM99</accession>
    <name>A0A1C7NM99_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">TRP C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_01843</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000063">
        <property type="protein sequence ID" value="OBZ90120.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NM99"/>
    <dbReference type="STRING" id="101091.A0A1C7NM99"/>
    <dbReference type="InParanoid" id="A0A1C7NM99"/>
    <dbReference type="OrthoDB" id="2448307at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040410">
        <property type="entry name" value="UPF0658_Golgi"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34391">
        <property type="entry name" value="UPF0658 GOLGI APPARATUS MEMBRANE PROTEIN C1952.10C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34391:SF1">
        <property type="entry name" value="UPF0658 GOLGI APPARATUS MEMBRANE PROTEIN C1952.10C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="84"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="109"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="155"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="202"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="235"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="264"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="292"/>
            <end position="320"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ90120.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="357" mass="40317" checksum="46CC4D59179C9E3B" modified="2016-11-30" version="1">MVTVTKIVDRVTETKWSKLYVSMATCQCLIIVALQAAICYLNTYQANLLPEPTTDSALTASSTPNDLIPIRAADRLGRIKWENIAFMGFQVWFLGMVFDATVYQNTAEILALAIINVVCAVLGALQVVDGVKWLKQLLLTPYPVNALDMAEKIEIALSVTILTFAIVMSFLSYQMSKQFGWNIYKKIGADVQIQKMYRMFQFFVLALKIDIFTCFMVSIFYLIQFALKQGLMWESVYQLIITISVIPMLCFARAAGSAESKPRMITFIVFECLVLFHFALILSQTIQPNNNWYTWIALVCLGIVATLCTCGLGLVCMVNFKKGLKPFVQRGNVKVKMDLENNLRKQKASDSWQIDDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NMD6</accession>
    <name>A0A1C7NMD6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Ribonuclease P protein subunit p30</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">RPP30_0</name>
        <name evidence="5" type="ORF">A0J61_02322</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the eukaryotic/archaeal RNase P protein component 3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000086">
        <property type="protein sequence ID" value="OBZ89616.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NMD6"/>
    <dbReference type="FunCoup" id="A0A1C7NMD6">
        <property type="interactions" value="446"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NMD6"/>
    <dbReference type="InParanoid" id="A0A1C7NMD6"/>
    <dbReference type="OrthoDB" id="17948at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005655">
        <property type="term" value="C:nucleolar ribonuclease P complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008033">
        <property type="term" value="P:tRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.140">
        <property type="entry name" value="Metal-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016195">
        <property type="entry name" value="Pol/histidinol_Pase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002738">
        <property type="entry name" value="RNase_P_p30"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13031:SF0">
        <property type="entry name" value="RIBONUCLEASE P PROTEIN SUBUNIT P30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13031">
        <property type="entry name" value="RIBONUCLEASE P SUBUNIT P30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01876">
        <property type="entry name" value="RNase_P_p30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89550">
        <property type="entry name" value="PHP domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0819">tRNA processing</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="241"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="241"/>
            <end position="254"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007331"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OBZ89616.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="269" mass="31022" checksum="489C980D98BC2952" modified="2016-11-30" version="1">MFYDFNIPYPNTSDATELQRIQKILDRIYSFNEQSTIALNLSIENNLTDVKPISPLLSQKFTNMQQLTRATLLVEDPKRNYQLAASSAYPKIDILAVRPTNIDMCKHVCQTLEVDLISLDLAKSRVVPGFTPAQVAINRGIFFEICYSQAFRDPSKKFQFYNNVKRLVEVTRGHNLLFSSEAMRALEVKRPADLRALGSMFGMTHDQIEATITVNYPRLLKKAETRKLTYNAVVSLDKDQLLQQEENKNKRKDNNQQQQSKKQKKQKKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NN34</accession>
    <name>A0A1C7NN34_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Minor extracellular protease vpr</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">vpr_4</name>
        <name evidence="13" type="ORF">A0J61_02057</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 9 10">Belongs to the peptidase S8 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000073">
        <property type="protein sequence ID" value="OBZ89886.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NN34"/>
    <dbReference type="InParanoid" id="A0A1C7NN34"/>
    <dbReference type="OrthoDB" id="10256524at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd07489">
        <property type="entry name" value="Peptidases_S8_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.200">
        <property type="entry name" value="Peptidase S8/S53 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046450">
        <property type="entry name" value="PA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003137">
        <property type="entry name" value="PA_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000209">
        <property type="entry name" value="Peptidase_S8/S53_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036852">
        <property type="entry name" value="Peptidase_S8/S53_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023827">
        <property type="entry name" value="Peptidase_S8_Asp-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022398">
        <property type="entry name" value="Peptidase_S8_His-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023828">
        <property type="entry name" value="Peptidase_S8_Ser-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050131">
        <property type="entry name" value="Peptidase_S8_subtilisin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015500">
        <property type="entry name" value="Peptidase_S8_subtilisin-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034187">
        <property type="entry name" value="Peptidases_S8_5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43806">
        <property type="entry name" value="PEPTIDASE S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43806:SF66">
        <property type="entry name" value="SERIN ENDOPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02225">
        <property type="entry name" value="PA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00082">
        <property type="entry name" value="Peptidase_S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00723">
        <property type="entry name" value="SUBTILISIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52025">
        <property type="entry name" value="PA domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52743">
        <property type="entry name" value="Subtilisin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51892">
        <property type="entry name" value="SUBTILASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00136">
        <property type="entry name" value="SUBTILASE_ASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00137">
        <property type="entry name" value="SUBTILASE_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00138">
        <property type="entry name" value="SUBTILASE_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0134">Cell wall</keyword>
    <keyword evidence="6 9 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 9 10" id="KW-0645">Protease</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0964">Secreted</keyword>
    <keyword evidence="7 9 10" id="KW-0720">Serine protease</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="domain" description="Peptidase S8/S53" evidence="11">
        <location>
            <begin position="108"/>
            <end position="527"/>
        </location>
    </feature>
    <feature type="domain" description="PA" evidence="12">
        <location>
            <begin position="326"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="8 9">
        <location>
            <position position="117"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="8 9">
        <location>
            <position position="167"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="8 9">
        <location>
            <position position="470"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022512"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR615500-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU003355"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF02225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="OBZ89886.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="868" mass="94133" checksum="67D0E85129819EC7" modified="2016-11-30" version="1">MFTKRALFYDQLDRHNINYKIRHEYEVINAVSVAFKSANDASLFFDKVKGVKKAWPVNTISKPRYSVTANNTMPVDITPELKNQVSSLFESYNTTGIKRVRDELGMTGSGIKVAIIDTGVDYTHPGLGGCFGKGCRVAYGYDFVGDAYTGENFPIPDEDPRDACNGHGTHVAGIIGANDILFNGVAPDVTFGAYRIFGCKGGSADDIIMKAMERAYLDGMDVVNLSLGDMGWPESPTSLLADELSLKGMIVVAAAGNEGEKGMFEVGTPSIGKHALSIASVDNTKVLSHTFTLGNTTIVYTTSQGNVFNFTSSELAFTSTEFTPKRDACEPLSIDLKNKVAVISRGGCIFMDKVLNAQKAGALGALIYNNDIGQLTPSAFNDAIHIDYGGISMQDGQLLFQTLNSTNRIALFQKHDISFPVPTAGYISDFSSWGLAPDLSLKPDLSAPGGHIYSTYPIGLGSYATLSGTSMATPFVAGIVALMLESRGGSKSINVTEVRHMLLNNGRPFEVFETKNQLNSVARQGAGLVDVYHAIVSDTVILPEQIKLSDLDHGSHNNEYTLTIKNNGRMMTEYKVGYLNAALAQAYQSRTINRNYENPDXSMDEDHLNATLRTILPLKKPKLIEQEAQAQANVEILGPDTFEIMANGEKNVTVRINPPANTTALPPSVYSGYITVTKVDDLSDVKYIPYAGLTNKLSQMPVLLVNRTMPNVIASYVSSTTPAFLSLQLLEASPIVSVSIVNATNLSHNFGLVPGGYARFLSKNDIFNPADFLLLPWYGNIVSSIEQASMGILGNRGGMINAAGNRLYHDVKKLGKSSDRAFGIEQLSAGKTLPGGTYKFKVMALRPLGDPDREQDYDIWYSPNIVKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NNI3</accession>
    <name>A0A1C7NNI3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Sodium/potassium exporting P-type ATPase 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">cta3_0</name>
        <name evidence="14" type="ORF">A0J61_01275</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000038">
        <property type="protein sequence ID" value="OBZ90692.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NNI3"/>
    <dbReference type="STRING" id="101091.A0A1C7NNI3"/>
    <dbReference type="InParanoid" id="A0A1C7NNI3"/>
    <dbReference type="OrthoDB" id="116380at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019829">
        <property type="term" value="F:ATPase-coupled monoatomic cation transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046873">
        <property type="term" value="F:metal ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015662">
        <property type="term" value="F:P-type ion transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140352">
        <property type="term" value="P:export from cell"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098662">
        <property type="term" value="P:inorganic cation transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="2.70.150.10:FF:000016">
        <property type="entry name" value="Calcium-transporting P-type ATPase putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1000:FF:000028">
        <property type="entry name" value="Calcium-transporting P-type ATPase, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.150.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, transmembrane domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006068">
        <property type="entry name" value="ATPase_P-typ_cation-transptr_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004014">
        <property type="entry name" value="ATPase_P-typ_cation-transptr_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023299">
        <property type="entry name" value="ATPase_P-typ_cyto_dom_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018303">
        <property type="entry name" value="ATPase_P-typ_P_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023298">
        <property type="entry name" value="ATPase_P-typ_TM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008250">
        <property type="entry name" value="ATPase_P-typ_transduc_dom_A_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059000">
        <property type="entry name" value="ATPase_P-type_domA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001757">
        <property type="entry name" value="P_typ_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044492">
        <property type="entry name" value="P_typ_ATPase_HD_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01494">
        <property type="entry name" value="ATPase_P-type"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42861">
        <property type="entry name" value="CALCIUM-TRANSPORTING ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13246">
        <property type="entry name" value="Cation_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00689">
        <property type="entry name" value="Cation_ATPase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00690">
        <property type="entry name" value="Cation_ATPase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00122">
        <property type="entry name" value="E1-E2_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00119">
        <property type="entry name" value="CATATPASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00120">
        <property type="entry name" value="HATPASE"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG00002">
        <property type="entry name" value="C1.7:_P-type_atpase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00003">
        <property type="entry name" value="Haloacid_Dehalogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00027">
        <property type="entry name" value="p-type_atpase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00831">
        <property type="entry name" value="Cation_ATPase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81653">
        <property type="entry name" value="Calcium ATPase, transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81665">
        <property type="entry name" value="Calcium ATPase, transmembrane domain M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81660">
        <property type="entry name" value="Metal cation-transporting ATPase, ATP-binding domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00154">
        <property type="entry name" value="ATPASE_E1_E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="9 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-1278">Translocase</keyword>
    <keyword evidence="3 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 12" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="57"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="84"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="248"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="275"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="755"/>
            <end position="775"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="787"/>
            <end position="810"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="831"/>
            <end position="852"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="884"/>
            <end position="901"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="922"/>
            <end position="941"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="953"/>
            <end position="973"/>
        </location>
    </feature>
    <feature type="domain" description="Cation-transporting P-type ATPase N-terminal" evidence="13">
        <location>
            <begin position="8"/>
            <end position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00038148"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00073741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="SMART" id="SM00831"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="OBZ90692.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="997" mass="111760" checksum="27F5EDD3B8A9C281" modified="2016-11-30" version="1">MDTTTITGWHTKSIEEVSKQLNTSLNDGLTESEAVQRQQVYGFNELESNQGATWIRILLRQFLDIMNWIFIALGAVSLGLKDYITGPILIVIALVNFYLTFQQEYAAEQTLAALKELSTPTAEVIRDGVPQTIASSDLVPGDILVLKEGDSVAADARLVYLSNLEVDEALLTGESVPVQKELTVLDDENEPLGDRKNMVYSSTFVSKGRGQAIVTSTGMKTEIGKVAEKLNDTDDGDRTQIQKGLHRMYVFLLAVGVVSIIVVFASVKFQLDYGIVMYAISAALSVLPAGLTTVLTLTLVIGGKEMTRHQAIVRKLKVLETLGSLTHIFSDKTGTLTMAKMVVVRFWTPQEGYFYVTPHGLAPQGETYRTFDKLDDNPLTTTGIELVEKKQLHTNEGITRLVECAALCNMSSIRRREHEEKELKVHRSLTKTSTRHSNVVIEIPAQEKDNTESDDWIPSGAPTEVALQVFAHKFDKGKPQLLENDGWELVQEYQFNSTIKKMSTVWYNRPLNYTVVFTKGATEKILSLCQGSESQKWQDEVMSHVDSLAAKGLRVIALAYRKEQGKSYDQSTDRDIIEKDLIFLGLTGIYDPPRPESRQAVKEAHQAGISVHMLTGDHVITATAIAKELNILNDTMPPEVLQELVMTGPQFDALTDEQTDSLAHLPFVVARCSPETKVKMIEASKRRSYIAAMTGDGVNDSPSLRKANVGIAMGKNGSDVAKQASDIILTDDNFATIIRAIAEGRRIYQNIQRFLLYYWISVLSLWFVLMVSLAFRDTDNRSVLPISTIQILFVFVVVTPPAGVLSVLPPSKTIMKEPPRSPKESLFNREIILDLLAYFLCLAFFSIISFIIPMYTRGHHGIEGSNCDSYFDYATCESLFRGRGMFLAYLSLASIIVMLHCRSYREPEFDMEGMKKTLKTKAVFFTFLFDIVCLVIFFYVPDVSQKGFYMLPISWEWAIVVAFLVLTIAYGEIYKLLKRRYLKPSKPHQFSPYILME</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NNM9</accession>
    <name>A0A1C7NNM9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_01247</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000037">
        <property type="protein sequence ID" value="OBZ90697.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NNM9"/>
    <dbReference type="InParanoid" id="A0A1C7NNM9"/>
    <dbReference type="OrthoDB" id="2290843at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ90697.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="148" mass="17290" checksum="C3DE7819D12AD07A" modified="2016-11-30" version="1">MHFYSNKQKLNELHTEYENVAQLRLDQLNAIQTQWQFYQEDTKPSRKKEILKRQADFEKDLELAQKESDSVVNQQAICHQLVDILKAQDRIQILNQSDSSDSTVDFSVVIIPHDILELFWSVGIKDVPVTKSDIPSTILYLEDMLKKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NNN6</accession>
    <name>A0A1C7NNN6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_01201</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000035">
        <property type="protein sequence ID" value="OBZ90753.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NNN6"/>
    <dbReference type="STRING" id="101091.A0A1C7NNN6"/>
    <dbReference type="InParanoid" id="A0A1C7NNN6"/>
    <dbReference type="OrthoDB" id="2287584at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="121"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="344"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="7"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="153"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="191"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="245"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="306"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="348"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="364"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="392"/>
            <end position="405"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ90753.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="674" mass="76194" checksum="EEF5737AC5E50792" modified="2016-11-30" version="1">MPLDYNTRVEDYHSDDGEAQMYSPSYRVNANDYENRRRRPSHPIDLQEEEEELERSMYEMDLNAYRHPPPRPRQYDPYLAPSYSPRRRPPPPLPPSYYLAPMPHERYRPWMHPMEERSPLYSPINRSPSSRSHMQRRNLPIPRRRYHEVYHDNEDEEEDYSDSEDDYPPRVPYGFPEANYAHDVSPARSYASRQSSIGSGQNLPLNKRRSNSFSIPPGMPRFVYPASPNVRRRPFQSAPNSPQASDGSNNSSSSSTDEEEEERHYIPRRRLSLGSNMPPPFVHPHHPPPRPPPQLRGNRRFSFSGVPPPPPPPNLPPVVLPTPSMMDNVNPSLPRRNSGFANDFFPNQNPPMPPPPPPPPPPQLAAAVAAAAVNGGAPPMNDPTTAAMPMPTANNPGNEMPSANQPGGAPWLNGAGNTNGLFHPMPMMGLAPMFNHPMMPPPPMWNMMNPTQQQQDPMWLGDFPFLNNQDPNLMTQTEVNRKSPVNPIETELPPTEEAQPNIAPAPEMMPPPTMIPPPQPPMLQRGLSMLGGLFSGSSYRRQPEFSNRGDDLYPPPPQLMNSKKEAKLAKEYAKLGTFYCWRKLDGTDAHFESFSIPNQKIIKRKLAKNAPSQIMLGKEKKLPGEIMVDLQQNRGCYLGKINGEQFLVQLEIKEETYHPANANSFVFATGENSW</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NNZ6</accession>
    <name>A0A1C7NNZ6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Endoplasmin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">Hsp90b1</name>
        <name evidence="9" type="ORF">A0J61_01128</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the heat shock protein 90 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000032">
        <property type="protein sequence ID" value="OBZ90835.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NNZ6"/>
    <dbReference type="STRING" id="101091.A0A1C7NNZ6"/>
    <dbReference type="InParanoid" id="A0A1C7NNZ6"/>
    <dbReference type="OrthoDB" id="28737at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd16927">
        <property type="entry name" value="HATPase_Hsp90-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.565.10:FF:000005">
        <property type="entry name" value="Heat shock protein 90"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11260">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.790">
        <property type="entry name" value="Heat shock protein 90, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="entry name" value="Histidine kinase-like ATPase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00505">
        <property type="entry name" value="HSP90"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037196">
        <property type="entry name" value="HSP90_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001404">
        <property type="entry name" value="Hsp90_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020575">
        <property type="entry name" value="Hsp90_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_Su5_D2-typ_SF"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003555">
        <property type="entry name" value="PRK05218.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11528">
        <property type="entry name" value="HEAT SHOCK PROTEIN 90 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13589">
        <property type="entry name" value="HATPase_c_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00183">
        <property type="entry name" value="HSP90"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002583">
        <property type="entry name" value="Hsp90"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00775">
        <property type="entry name" value="HEATSHOCK90"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110942">
        <property type="entry name" value="HSP90 C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="Ribosomal protein S5 domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0143">Chaperone</keyword>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008889809" evidence="7">
        <location>
            <begin position="23"/>
            <end position="762"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase/HSP90-like ATPase" evidence="8">
        <location>
            <begin position="72"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="719"/>
            <end position="749"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="79"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="83"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="125"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="130"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="138"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="144"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="145"/>
            <end position="146"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="167"/>
            <end position="172"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="220"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="415"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR002583-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OBZ90835.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="762" mass="87367" checksum="BECB4DFCED9EE63F" modified="2016-11-30" version="1">MRFKSLYITFLLAISCILLVRADANSEQASVSAGLPQDISPEQLDTISSEKFTFQTEVSRLMHLIINSLYKTREIFLRELISNASDALDKIRFMSLTDPESLATNPDLHITIAADQERKALIITDTGIGMTREQLKENLGTIAKSGTSEFLAKMEKNKNDAITQIGQFGVGFYSVFLVADRVTVASKSNNDPDQHIWMSTAVDDFKIAKDPRGNTLKRGTQITLYLKPDAYRFLEEKKLQELVQKYSQFITFPILLWTGEEKEVPVDSELDSLLSDEMTEEDLSDHKKDTKTEKRMVYNWNQINLQKPIWMRDPKDISDEEHNEFFKSLTRQTSNPLGWTLYKGEGEIEFRSLLYIPPRIDEKFYQNAQRDESNKPIKLFVKRVFISDEVDLLPRWLSFLKGIVDADDLPLNVSRETLQKHRSLRTITRHLVKKALDMFTQLSQNDPKSFTKFLTQYGSILKYGAIEDQPYRKKITSLLRFATSHNTTAFSSSLDDYIDRAKAEQTSIYYMTGNTISEIEQSPFIESLLARGYEIIYFTDPIDETFVQNIPGYNGKQFVNIAKGDLSFNDDDTQTDTALETKYKPLTVWLVDTLYENIDKAVISRRLTTSPLAIVAPRDGLSGHAQRILDAQGMNIKDPNLEFMLQSMRSQKKTLEINPNHPVIKTLLEYVEKDKVTDEMINLIQLMYDTTAIRSGFPLHDLNQFAGRVEGLIRKAVGVSILEEAKVDVKKANEKTEEERKADEELKKTNIVYEDTIEHDEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NP54</accession>
    <name>A0A1C7NP54_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Gamma-aminobutyric acid type B receptor subunit 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">GABBR2</name>
        <name evidence="12" type="ORF">A0J61_01711</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000057">
        <property type="protein sequence ID" value="OBZ90246.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NP54"/>
    <dbReference type="STRING" id="101091.A0A1C7NP54"/>
    <dbReference type="InParanoid" id="A0A1C7NP54"/>
    <dbReference type="OrthoDB" id="5984008at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0038039">
        <property type="term" value="C:G protein-coupled receptor heterodimeric complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004965">
        <property type="term" value="F:G protein-coupled GABA receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007214">
        <property type="term" value="P:gamma-aminobutyric acid signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd15047">
        <property type="entry name" value="7tmC_GABA-B-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001828">
        <property type="entry name" value="ANF_lig-bd_rcpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002455">
        <property type="entry name" value="GPCR3_GABA-B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000337">
        <property type="entry name" value="GPCR_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017978">
        <property type="entry name" value="GPCR_3_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028082">
        <property type="entry name" value="Peripla_BP_I"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10519:SF20">
        <property type="entry name" value="G-PROTEIN COUPLED RECEPTOR 156-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10519">
        <property type="entry name" value="GABA-B RECEPTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00003">
        <property type="entry name" value="7tm_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01094">
        <property type="entry name" value="ANF_receptor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01176">
        <property type="entry name" value="GABABRECEPTR"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00248">
        <property type="entry name" value="GPCRMGR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53822">
        <property type="entry name" value="Periplasmic binding protein-like I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50259">
        <property type="entry name" value="G_PROTEIN_RECEP_F3_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0297">G-protein coupled receptor</keyword>
    <keyword evidence="7" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="6 12" id="KW-0675">Receptor</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0807">Transducer</keyword>
    <keyword evidence="2 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="482"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="516"/>
            <end position="539"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="545"/>
            <end position="567"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="588"/>
            <end position="608"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="636"/>
            <end position="658"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="678"/>
            <end position="697"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="703"/>
            <end position="725"/>
        </location>
    </feature>
    <feature type="domain" description="G-protein coupled receptors family 3 profile" evidence="11">
        <location>
            <begin position="479"/>
            <end position="729"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="794"/>
            <end position="819"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="796"/>
            <end position="809"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50259"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="OBZ90246.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="1007" mass="112921" checksum="A8330DDEBEACF556" modified="2016-11-30" version="1">MTTFNSTSSIFGKQLTDDLYNAYNQTDNSTVFITPRYNTTGKIELKIGVLLPFTQKKDDLTAQIVWGGSSAIRMAVNEINNKQIIPGAYVTLIQKDSFPDASLDQMAVTNAVYASVTLLQQGVIGVIGDISSSWTSLSAIMTSTLEIPQCSYTANAIAFSDKSQYSHFFRTIPTQVIIADVMLSFVSTQGWKKLGVIYTDDPLGQQFYQKSLVQAKAMNINIMHFQALSTASTIDNINTALINITDSGARIIMVAATAVPQSQLLIQAHELGLLSNDYVWLMMGDTTKELKSSIDSYNKNHSKTIDYATDYQGLFLFDNWLSLEGYPPFEEFLDRWAMLDPNTYPYAGQRNISSYEGLAYSCMMVMAEGFGKKIAESRNQTDQLLKLVNGGLGEEMVPTSFNVGYVGPEGKMTYDLNGDLTTGNYLVYNLQQGHKAVIGKSTGGLLNMTSLPMFFDGTSQPPQDSPPSAALNPNIDSSISRVILAISSIGVLFATFCFLVVLLYRKHEVFKASSPLFCCLELVGFILTYFSVVTMIGIPTATTCIVTPATFTLGFVLVLGNMIAKNYRIYRIFNNIFITRNVITDSHVTKTVFSLVAVDVIILVIGLATTRPFPEKIEITSSSHYWMCEAQGGSKVVFLVLFVIYAAILLLFATFLAAKTRSAGTQYQRYRECKQMGFSVYNILLCAVIGFVVSVIPDTTFYTRYYFSVTVTLWATSFSMFIVFVPKLHDFFQHKITEELQNQMKKETTLDKKRKPLLSFLKSRAATHHLQDHHMEYGNELLSLDQILASSHPVLDEDDEDEEEEEGQEENDHQLRRRKASAVSAASTTYYKNGQGNLIEIHEGELPVRKAFRYFPFLSQWEMHHIMVFPWLNYFSHFSKDAKKGTVMSYSHATIYSTKLEDYVLKIHGQGWSDMYIQLPSLNSLHTWEQCFSQKKPEFLSAAPIQLKPPVPPIPSLQQMDMITHPHDMLASSMSQDHLLRRLSDQSEEVISNSNTAVMPMHAHIKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-06-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NPD5</accession>
    <name>A0A1C7NPD5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_01095</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000031">
        <property type="protein sequence ID" value="OBZ90850.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NPD5"/>
    <dbReference type="InParanoid" id="A0A1C7NPD5"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ90850.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="62" mass="7436" checksum="259E810CF2B18A0E" modified="2016-11-30" version="1">MSLVIDLRPKHKVFDHYQLTIDLQRKFLFTKDNSCFMPSQVLCNILSEFEANAAYLKHIHYY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NPU8</accession>
    <name>A0A1C7NPU8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_02686</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000104">
        <property type="protein sequence ID" value="OBZ89274.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NPU8"/>
    <dbReference type="STRING" id="101091.A0A1C7NPU8"/>
    <dbReference type="InParanoid" id="A0A1C7NPU8"/>
    <dbReference type="OrthoDB" id="2137681at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="39"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="9"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="47"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="63"/>
            <end position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ89274.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="710" mass="82104" checksum="5F7D7206C00419A9" modified="2016-11-30" version="1">MTEVGASPEKYKQIRSDDEAFEPPPLFGNFFEGWSSFFSSGNQKPKKSNEDASRHGKDQSSFDSEESSTSSDDESSFYCTGEEENDSKEVFHRSTRRKSSVRVGKRIISELLENENVSKAIRILQKALDHLETTQVDSEDGQEFSRIYSQIIHSLCDPNIFAVVKEVSKRSDGKEVDIRESVMWRLFTKVVESGYVLQTEAHLAVVNLLIENENKSLALQAMYALPRREWDITCYRIALLLHLMQEPKQVEEAQGLLFDFGRPHLDIANPIEPNDLPPIHIEMPLMKNVTELDQFNLWMFYQAALSNSNSEWNYTKEAFETTRQEYLEALEQERSSIKDWAMEHLHIETRRQQIDRMSTEHDNAMIYSAIKNSQFEYGWHVYEAMEDAVNESTPCIVMHLCWVAFRQIPFADISRRKGWEERGWSVYSRFMCSEYLHPEQTEAPSFLHDILSIAANSPESTADKKARYTKTMSVYQLLVRLEFDKLLCNDRVLEPILCTLLYECKGIPSHVICMCNKAFELWDRKMEILRRETGKEFRISSVSIIWALLIFCLKSGDQCHFEKILQLLLDNDVLEDLPSSLLAPIQTYHDKYQCEDCYFTSYMFKPIAYTDKGLKQPTYMDSFGLIHTLETNVDNAKSRRHGRPLSGAFAHDDLRPNIDEIQAGLIATSVIMGPAKHEDMLPKQMYFSTKKAKAVVRHCLKRDQRNAADA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NPV8</accession>
    <name>A0A1C7NPV8_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">A0J61_00776</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000020">
        <property type="protein sequence ID" value="OBZ91155.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NPV8"/>
    <dbReference type="STRING" id="101091.A0A1C7NPV8"/>
    <dbReference type="InParanoid" id="A0A1C7NPV8"/>
    <dbReference type="OrthoDB" id="654211at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000785">
        <property type="term" value="C:chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031519">
        <property type="term" value="C:PcG protein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005667">
        <property type="term" value="C:transcription regulator complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:002343">
        <property type="entry name" value="Zinc finger protein 33A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14003:SF22">
        <property type="entry name" value="FINGER DOMAIN PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_4G11480)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14003">
        <property type="entry name" value="TRANSCRIPTIONAL REPRESSOR PROTEIN YY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="6">
        <location>
            <begin position="49"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="6">
        <location>
            <begin position="84"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="6">
        <location>
            <begin position="114"/>
            <end position="144"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OBZ91155.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="154" mass="17930" checksum="22DF647D9ACE1916" modified="2016-11-30" version="1">MDISKLLVQNTEIITSLTNQKKPSTKKRHASRPSDMTRHYRIHTNDRPYQCPLDFCGKRFIQHAMKQRSALTVHQRTHSGEKPHICKYPSCNKSFADSSALARHRRIHSQPRLFVCVEPNCSKSYIKKSHLTRHLRRGHPNTQTYASIVTCLRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NQG3</accession>
    <name>A0A1C7NQG3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Versiconal hemiacetal acetate reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">vrdA_1</name>
        <name evidence="3" type="ORF">A0J61_00577</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000013">
        <property type="protein sequence ID" value="OBZ91365.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NQG3"/>
    <dbReference type="FunCoup" id="A0A1C7NQG3">
        <property type="interactions" value="24"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NQG3"/>
    <dbReference type="InParanoid" id="A0A1C7NQG3"/>
    <dbReference type="OrthoDB" id="37537at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd19079">
        <property type="entry name" value="AKR_EcYajO-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.100:FF:000004">
        <property type="entry name" value="Oxidoreductase, aldo/keto reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="entry name" value="NADP-dependent oxidoreductase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050523">
        <property type="entry name" value="AKR_Detox_Biosynth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036812">
        <property type="entry name" value="NAD(P)_OxRdtase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023210">
        <property type="entry name" value="NADP_OxRdtase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43364:SF4">
        <property type="entry name" value="NAD(P)-LINKED OXIDOREDUCTASE SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43364">
        <property type="entry name" value="NADH-SPECIFIC METHYLGLYOXAL REDUCTASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00248">
        <property type="entry name" value="Aldo_ket_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51430">
        <property type="entry name" value="NAD(P)-linked oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NADP-dependent oxidoreductase" evidence="2">
        <location>
            <begin position="25"/>
            <end position="339"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ91365.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="348" mass="39370" checksum="46092A23CBA9738A" modified="2016-11-30" version="1">MTSQTKPATKMQYVRLGNTGLRVSRICLGCMSYGNSRWSPWVKEEAESIADIKEAYNLGINFFDTADTYSNGDSERILGKALKEINAPRGRVVVATKVFAPVYDDTGFSSRDSVKNNPDMVNRHGLSRKHILDAVDASLERLGLDYIDLYQIHRLDTDTPMEEIMEALNDVVRSGKVRYIGASSMAAWQFQKLNNIAERHGWAKFVSMQNLYNMLYREEEREMAPYCLDAGIAWIPWSPLAMGELAGKNRGKTTRSDTWFSMKSMTATQAECNEVIVDRLEEIAKKHNATCAQVALAWQFTKPYVSSPIIGASKIEHLYDIVGSLDVKLSEEDVKYLEEPYTPKRAMF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NQH7</accession>
    <name>A0A1C7NQH7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">A0J61_00726</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the UPF0014 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000018">
        <property type="protein sequence ID" value="OBZ91220.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NQH7"/>
    <dbReference type="InParanoid" id="A0A1C7NQH7"/>
    <dbReference type="OrthoDB" id="432685at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005226">
        <property type="entry name" value="UPF0014_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30028:SF0">
        <property type="entry name" value="PROTEIN ALUMINUM SENSITIVE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30028">
        <property type="entry name" value="UPF0014 INNER MEMBRANE PROTEIN YBBM-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03649">
        <property type="entry name" value="UPF0014"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="31"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="58"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="83"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="117"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="150"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="217"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="248"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="322"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="336"/>
            <end position="345"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OBZ91220.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="345" mass="37687" checksum="554EFE5573255698" modified="2016-11-30" version="1">MDSSTILDFVANITTIGQEGDKPSAAPTLSWINVAIASSFILINGGISLVLGLKLEKTLIVAAVRCLIQLTIMGFILEDVFKARHPALVLFMTFVLILLGAYETVYNKSKQSYKGMFLSVLVSSGIATLVVGIIGTRFAMKQKPFWIPEIFIPTMGMLLGNAMSGMAVALSSVLSSVSNRREQIETYLAFGASRWEAGQSIAIEAVRLSMLPTINQMSVIGLIAIPGMMTGQILGGAPVSNAVKYQQIIMFLISASTALGVLSAVVTSIRAMIDNRHRLRPERIINGRASLFQDIKGLFVSAWHGIAYILCCMPFRKDKKGKYNPVDQEDDDEHNEDQRRPLLNN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NQS5</accession>
    <name>A0A1C7NQS5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_00446</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000010">
        <property type="protein sequence ID" value="OBZ91471.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NQS5"/>
    <dbReference type="InParanoid" id="A0A1C7NQS5"/>
    <dbReference type="OrthoDB" id="5430106at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031931">
        <property type="term" value="C:TORC1 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031929">
        <property type="term" value="P:TOR signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018857">
        <property type="entry name" value="TORC1_cplx_su_TCO89"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10452">
        <property type="entry name" value="TCO89"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="136"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="142"/>
            <end position="155"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ91471.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="155" mass="18293" checksum="272CC176AEDC8C8F" modified="2016-11-30" version="1">MEPIKLLYTTSLPSTQLTMHTAHAQAIDHQDMSFVIEKKPATKTEMSRTQHKLMLQRQSFLADDRNYLEHPDNMRKLTRELDRVNREYRHLKQFQDPFVLSLKRVILQESICSSPPQLERRGSSSTFHDYLMHMKEERRHSSSSLQSHSKAFSHS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NR50</accession>
    <name>A0A1C7NR50_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="19">Histidine biosynthesis trifunctional protein</fullName>
        </recommendedName>
        <domain>
            <recommendedName>
                <fullName evidence="19">Phosphoribosyl-AMP cyclohydrolase</fullName>
                <ecNumber evidence="19">3.5.4.19</ecNumber>
            </recommendedName>
        </domain>
        <domain>
            <recommendedName>
                <fullName evidence="19">Phosphoribosyl-ATP pyrophosphohydrolase</fullName>
                <ecNumber evidence="19">3.6.1.31</ecNumber>
            </recommendedName>
        </domain>
        <domain>
            <recommendedName>
                <fullName evidence="19">Histidinol dehydrogenase</fullName>
                <shortName evidence="19">HDH</shortName>
                <ecNumber evidence="19">1.1.1.23</ecNumber>
            </recommendedName>
        </domain>
    </protein>
    <gene>
        <name evidence="22" type="primary">HIS4</name>
        <name evidence="22" type="ORF">A0J61_02207</name>
    </gene>
    <organism evidence="22 23">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="22 23" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="22 23">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 19">
            <text>1-(5-phospho-beta-D-ribosyl)-5'-AMP + H2O = 1-(5-phospho-beta-D-ribosyl)-5-[(5-phospho-beta-D-ribosylamino)methylideneamino]imidazole-4-carboxamide</text>
            <dbReference type="Rhea" id="RHEA:20049"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:58435"/>
            <dbReference type="ChEBI" id="CHEBI:59457"/>
            <dbReference type="EC" id="3.5.4.19"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2 19">
            <text>1-(5-phospho-beta-D-ribosyl)-ATP + H2O = 1-(5-phospho-beta-D-ribosyl)-5'-AMP + diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:22828"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:59457"/>
            <dbReference type="ChEBI" id="CHEBI:73183"/>
            <dbReference type="EC" id="3.6.1.31"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="18 19">
            <text>L-histidinol + 2 NAD(+) + H2O = L-histidine + 2 NADH + 3 H(+)</text>
            <dbReference type="Rhea" id="RHEA:20641"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57595"/>
            <dbReference type="ChEBI" id="CHEBI:57699"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.1.1.23"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="6">Amino-acid biosynthesis; L-histidine biosynthesis; L-histidine from 5-phospho-alpha-D-ribose 1-diphosphate: step 2/9.</text>
    </comment>
    <comment type="pathway">
        <text evidence="5">Amino-acid biosynthesis; L-histidine biosynthesis; L-histidine from 5-phospho-alpha-D-ribose 1-diphosphate: step 3/9.</text>
    </comment>
    <comment type="pathway">
        <text evidence="4">Amino-acid biosynthesis; L-histidine biosynthesis; L-histidine from 5-phospho-alpha-D-ribose 1-diphosphate: step 9/9.</text>
    </comment>
    <comment type="similarity">
        <text evidence="7 19">In the C-terminal section; belongs to the histidinol dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="22">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.5.4.19" evidence="19"/>
    <dbReference type="EC" id="3.6.1.31" evidence="19"/>
    <dbReference type="EC" id="1.1.1.23" evidence="19"/>
    <dbReference type="EMBL" id="LUGH01000080">
        <property type="protein sequence ID" value="OBZ89734.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NR50"/>
    <dbReference type="FunCoup" id="A0A1C7NR50">
        <property type="interactions" value="488"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NR50"/>
    <dbReference type="InParanoid" id="A0A1C7NR50"/>
    <dbReference type="OrthoDB" id="1703565at2759"/>
    <dbReference type="UniPathway" id="UPA00031">
        <property type="reaction ID" value="UER00007"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004399">
        <property type="term" value="F:histidinol dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004635">
        <property type="term" value="F:phosphoribosyl-AMP cyclohydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004636">
        <property type="term" value="F:phosphoribosyl-ATP diphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000105">
        <property type="term" value="P:L-histidine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd06572">
        <property type="entry name" value="Histidinol_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd11546">
        <property type="entry name" value="NTP-PPase_His4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.1080:FF:000002">
        <property type="entry name" value="Histidine biosynthesis bifunctional protein HisIE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.5.1300:FF:000001">
        <property type="entry name" value="Histidine biosynthesis trifunctional protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.20.810:FF:000002">
        <property type="entry name" value="Histidine biosynthesis trifunctional protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1980:FF:000050">
        <property type="entry name" value="Histidine biosynthesis trifunctional protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1980:FF:000001">
        <property type="entry name" value="Histidinol dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.1300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.1080">
        <property type="entry name" value="MazG-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1980">
        <property type="entry name" value="Nitrogenase molybdenum iron protein domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.810">
        <property type="entry name" value="Phosphoribosyl-AMP cyclohydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01024">
        <property type="entry name" value="HisD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016161">
        <property type="entry name" value="Ald_DH/histidinol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008179">
        <property type="entry name" value="HisE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016298">
        <property type="entry name" value="Histidine_synth_trifunct"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001692">
        <property type="entry name" value="Histidinol_DH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012131">
        <property type="entry name" value="Hstdl_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021130">
        <property type="entry name" value="PRib-ATP_PPHydrolase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002496">
        <property type="entry name" value="PRib_AMP_CycHydrolase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038019">
        <property type="entry name" value="PRib_AMP_CycHydrolase_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00069">
        <property type="entry name" value="hisD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR03188">
        <property type="entry name" value="histidine_hisI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21256:SF2">
        <property type="entry name" value="HISTIDINE BIOSYNTHESIS TRIFUNCTIONAL PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21256">
        <property type="entry name" value="HISTIDINOL DEHYDROGENASE HDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00815">
        <property type="entry name" value="Histidinol_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01502">
        <property type="entry name" value="PRA-CH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01503">
        <property type="entry name" value="PRA-PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001257">
        <property type="entry name" value="His_trifunctional"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00083">
        <property type="entry name" value="HOLDHDRGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53720">
        <property type="entry name" value="ALDH-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101386">
        <property type="entry name" value="all-alpha NTP pyrophosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141734">
        <property type="entry name" value="HisI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00611">
        <property type="entry name" value="HISOL_DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 19" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="13 19" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="16 19" id="KW-0368">Histidine biosynthesis</keyword>
    <keyword evidence="11 19" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="17" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="15 19" id="KW-0520">NAD</keyword>
    <keyword evidence="10 19" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14 19" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="23" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="12" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Phosphoribosyl-AMP cyclohydrolase" evidence="21">
        <location>
            <begin position="213"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="20">
        <location>
            <begin position="374"/>
            <end position="399"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004940"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00005169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00005204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00008260"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00049489"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="PIRNR" id="PIRNR001257"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="21">
        <source>
            <dbReference type="Pfam" id="PF01502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="EMBL" id="OBZ89734.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="849" mass="92172" checksum="76D42835D650E72C" modified="2016-11-30" version="1">MFVPSLDLAEASQASLYSSVSFFSSVILKNGGVDQIKSLVNQTGSTLYWAFANSLEEAIQLWDVGVLKVIFSLDVYLQAKDELASIVTEDRIAISTDSVSSLENLPVSTFIIRNNSDLDAIRAFAQSTKKCLLGHGGERNVVIELENVSVEAIASFGAEHIDVLVPASRLTTAVDDASKINIAEAFLATAKTDRSDGLYTTMVVDEFNKALGLVYSSKQSVAESIRLGQGVYQSRGRGLWHKGLTSGATQTLKHVDYDCDGDALRFVVEQHGAGFCHLNTRTCFGADSGITALEKTLKDRKKNAPAGSYTARLFGDAKLLRAKIMEEAEELCDATDKDEVAWEAADLIYFALTKCVSAGVSLTDIEKNLNKKARKVTRRPGNAKPKWEQKEDAAAPVAPSAPVNATAINEGRIEMMKFDLENISAEKRAELLLRPIIDSSEIINRVQPIMKEVRTNGDKAIRNFTRQFDRVELDKVTIEAPFDPAMMELDPITKAAIDQAYDNIYKFHDAQLDKEMLVVETMPGVVCSRFSRPIERVGLYVPGGSAVLPSTTLMLGIPAKVAGCKEIVIATPPRSDGSIVPEVLYVAHKVGASHVVKAGGAQAVAAMAYGTETVPKVDKIFGPGNQYVTAAKMVAQNDTSCLVSIDMPAGPSEVLVIADKTSNPVYVAADLLSQAEHGPDSQVVLLAVDLSEEHLRSIEDEVHKQALALPRCDIVRKSIPHSYSLSMKTLEEAMQFSNEYAPEHLILHLENAASVLPMVDNAGSVFVGQYSPESFGDYASGTNHTLPTYGYSRMYSGVNTNGFVKHITSQEVTAEGMDRLADTVMRLAEIEGLEAHRNAVAVRVADIRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-06-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NRA8</accession>
    <name>A0A1C7NRA8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_02161</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000078">
        <property type="protein sequence ID" value="OBZ89784.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NRA8"/>
    <dbReference type="InParanoid" id="A0A1C7NRA8"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ89784.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="64" mass="7596" checksum="7D1C468F907FE6B4" modified="2016-11-30" version="1">MYSLSLERVLSLTEIHLRHVRHILISTEPKENLIDLGIFGLIAQYFRSSTETLFDIRYKEQQEC</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NRB5</accession>
    <name>A0A1C7NRB5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">fumarate hydratase</fullName>
            <ecNumber evidence="2">4.2.1.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">FUMR_0</name>
        <name evidence="7" type="ORF">A0J61_00241</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Catalyzes the reversible stereospecific interconversion of fumarate to L-malate. In mitochondrion, catalyzes the hydration of fumarate to L-malate in the tricarboxylic acid (TCA) cycle to facilitate a transition step in the production of energy in the form of NADH. In cytoplasm and nucleus, involved in DNA repair in response to DNA damage: following DNA double-strand breaks (DSBs), translocates from the cytosol to the nucleus and promotes DNA repair by catalyzing the dehydration of L-malate to fumarate.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.2" evidence="2"/>
    <dbReference type="EMBL" id="LUGH01000005">
        <property type="protein sequence ID" value="OBZ91677.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NRB5"/>
    <dbReference type="FunCoup" id="A0A1C7NRB5">
        <property type="interactions" value="426"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NRB5"/>
    <dbReference type="InParanoid" id="A0A1C7NRB5"/>
    <dbReference type="OrthoDB" id="1738025at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004333">
        <property type="term" value="F:fumarate hydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006106">
        <property type="term" value="P:fumarate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006108">
        <property type="term" value="P:malate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01362">
        <property type="entry name" value="Fumarase_classII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.40.30:FF:000002">
        <property type="entry name" value="Fumarate hydratase class II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.275.10:FF:000001">
        <property type="entry name" value="Fumarate hydratase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.200.10:FF:000001">
        <property type="entry name" value="Fumarate hydratase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.40.30">
        <property type="entry name" value="Fumarase/aspartase (C-terminal domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.200.10">
        <property type="entry name" value="Fumarase/aspartase (Central domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.275.10">
        <property type="entry name" value="Fumarase/aspartase (N-terminal domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00743">
        <property type="entry name" value="FumaraseC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005677">
        <property type="entry name" value="Fum_hydII"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024083">
        <property type="entry name" value="Fumarase/histidase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018951">
        <property type="entry name" value="Fumarase_C_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020557">
        <property type="entry name" value="Fumarate_lyase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000362">
        <property type="entry name" value="Fumarate_lyase_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022761">
        <property type="entry name" value="Fumarate_lyase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008948">
        <property type="entry name" value="L-Aspartase-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00979">
        <property type="entry name" value="fumC_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF008909">
        <property type="entry name" value="PRK12273.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11444">
        <property type="entry name" value="ASPARTATEAMMONIA/ARGININOSUCCINATE/ADENYLOSUCCINATE LYASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11444:SF1">
        <property type="entry name" value="FUMARATE HYDRATASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10415">
        <property type="entry name" value="FumaraseC_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00206">
        <property type="entry name" value="Lyase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00145">
        <property type="entry name" value="ARGSUCLYASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00149">
        <property type="entry name" value="FUMRATELYASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48557">
        <property type="entry name" value="L-aspartase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00163">
        <property type="entry name" value="FUMARATE_LYASES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0456">Lyase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fumarate lyase N-terminal" evidence="5">
        <location>
            <begin position="40"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="domain" description="Fumarase C C-terminal" evidence="6">
        <location>
            <begin position="430"/>
            <end position="482"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009084"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012921"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00056821"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF10415"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OBZ91677.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="485" mass="53128" checksum="C57C367BF70E2B62" modified="2016-11-30" version="1">MIDRHHIYFQQTNCVLLFFSHFFSANTMSTEFRIETDSFGEINVPAQVYWGAQTQRSFENFKIGGAEERMPSALIKAFGILKKAAAKVNLEFGMDPKVSEAIQQAATEVIDGKLNDQFPLVVWQTGSGTQTHMNVNEVISNRAIEILGGQVGSKTPVHPNDHVNIFPTAMHIAAVVEINQDLIPALTELRDALKAKSDEFQDIIKIGRTHLQDATPLTLGQEFSGYVQQLTYGIERVQATLPRLSRLAQGGTAVGTGLNTHKGFDVKIAHTVSELTGYSFETAPNKFEALASNDAMVECSGALNTIAVSLMKIANDIRFLGSGPRCGLGELSLPENEPGSSIMPGKVNPTQCEALTMVCAQVMGNHTTVTVSGSYGHFELNVFKPVIIKNVLQSIRLLSDACRSFKKNCVVGIIANRDHIKNTMNRSLMLVTSLNPYIGYDKAAQCAKKAHKEGITLKESVLALGYLTSEEYDNYVRPENMISPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NRF9</accession>
    <name>A0A1C7NRF9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_00186</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000004">
        <property type="protein sequence ID" value="OBZ91725.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NRF9"/>
    <dbReference type="STRING" id="101091.A0A1C7NRF9"/>
    <dbReference type="InParanoid" id="A0A1C7NRF9"/>
    <dbReference type="OrthoDB" id="2381286at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="149"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="40"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="149"/>
            <end position="164"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ91725.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="284" mass="32702" checksum="E6BCABB8F5E03F3E" modified="2016-11-30" version="1">MPTTNRSRPVSEQWKTSSSANNLQLESWKMSGKPRHAQLQPFQDTKRYSSTPTMMSNNSPWPTKPLPAEPIVQPAHLIIPGQMEENFHPPFYLNNTTLSHSHHSYPNYAYATTLYDMTSIPPQQHLQQQTIDAHNIEYPPMTDYYQPPYMPPQPSYLPPQPPSPVTQEPAVEKPKKNEKKIRQITVQSINAEHRVWIDVLPSETGLSLAEKIHVIATFRTRKVVSITTASGRKITLDNRPVFGSWMDMESFQDGERWTVEWRENDRGMVDKLLSKMIQVTRGEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NRS1</accession>
    <name>A0A1C7NRS1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">HIG1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">A0J61_00155</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000003">
        <property type="protein sequence ID" value="OBZ91803.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NRS1"/>
    <dbReference type="FunCoup" id="A0A1C7NRS1">
        <property type="interactions" value="60"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NRS1"/>
    <dbReference type="InParanoid" id="A0A1C7NRS1"/>
    <dbReference type="OrthoDB" id="1915122at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033617">
        <property type="term" value="P:mitochondrial respiratory chain complex IV assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007667">
        <property type="entry name" value="Hypoxia_induced_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040153">
        <property type="entry name" value="Rcf2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28018">
        <property type="entry name" value="RESPIRATORY SUPERCOMPLEX FACTOR 2, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28018:SF3">
        <property type="entry name" value="RESPIRATORY SUPERCOMPLEX FACTOR 2, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04588">
        <property type="entry name" value="HIG_1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51503">
        <property type="entry name" value="HIG1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="21"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="52"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="118"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="153"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="domain" description="HIG1" evidence="6">
        <location>
            <begin position="90"/>
            <end position="181"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51503"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OBZ91803.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="208" mass="22892" checksum="BD9500D2CC8F7406" modified="2016-11-30" version="1">MTKYLTAEQEKIRDRIYYQSGAKGALIGLGLGAVATAFVLKRSPEFRALSRPLQSIMAASTTTAGFLFASDKATQEFENRELGYTDEDMIAALRRGEKPQDNLSTFDRSMQYLNSNRWSVIGLSWAVSMAGALGLSFSNRYLTTQQKLVQARMYAQAVTIAVLMASAGVSIYVGDEGKDRKEEPDAQLRAVLALPDNSEPKMVKQTSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NRU5</accession>
    <name>A0A1C7NRU5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_00247</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000005">
        <property type="protein sequence ID" value="OBZ91680.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NRU5"/>
    <dbReference type="InParanoid" id="A0A1C7NRU5"/>
    <dbReference type="OrthoDB" id="2282800at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="64"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="215"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="86"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="215"/>
            <end position="228"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ91680.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="260" mass="30064" checksum="736B62D46D7D89E3" modified="2016-11-30" version="1">MNSREEEFSISFGSEQGSHLLLLDSEDGSDITPPPLANPPSDASYSSSFLDMVKQSVERAQILYRSKEEESDSFDSILHFGSSQENEDKSEERVERGRREKDREPAFVPVGFESQQSHESMPEFAVLREDPLSVTHLRYTTNKRKKKEQQVKMALEAAHAQLLSETEKEPFLYFIQAQTDKESEEDLNEESDDDFSSWLCFDSQGSYAKFKHDIDDKVNQMDKPKQTEEQEEDESFSDLQQKIMMTSTPKRMFDLSKKRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NRY6</accession>
    <name>A0A1C7NRY6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="10 11">Cytochrome c oxidase subunit 8, mitochondrial</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">Cytochrome c oxidase polypeptide VIII</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="primary">COX7C</name>
        <name evidence="12" type="ORF">A0J61_00011</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 11">Energy metabolism; oxidative phosphorylation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="11">Component of the cytochrome c oxidase (complex IV, CIV), a multisubunit enzyme composed of a catalytic core of 3 subunits and several supernumerary subunits. The complex exists as a monomer or a dimer and forms supercomplexes (SCs) in the inner mitochondrial membrane with ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 11">Mitochondrion inner membrane</location>
            <topology evidence="1 11">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 11">Belongs to the cytochrome c oxidase VIIc family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000001">
        <property type="protein sequence ID" value="OBZ91882.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NRY6"/>
    <dbReference type="STRING" id="101091.A0A1C7NRY6"/>
    <dbReference type="InParanoid" id="A0A1C7NRY6"/>
    <dbReference type="OrthoDB" id="9974841at2759"/>
    <dbReference type="UniPathway" id="UPA00705"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045277">
        <property type="term" value="C:respiratory chain complex IV"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006123">
        <property type="term" value="P:mitochondrial electron transport, cytochrome c to oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="4.10.49.10:FF:000001">
        <property type="entry name" value="Cytochrome c oxidase subunit 7C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.49.10">
        <property type="entry name" value="Cytochrome c oxidase subunit VIIc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004202">
        <property type="entry name" value="COX7C/Cox8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036636">
        <property type="entry name" value="COX7C/Cox8_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13313:SF0">
        <property type="entry name" value="CYTOCHROME C OXIDASE SUBUNIT 7C, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13313">
        <property type="entry name" value="CYTOCHROME C OXIDASE SUBUNIT VIIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02935">
        <property type="entry name" value="COX7C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81427">
        <property type="entry name" value="Mitochondrial cytochrome c oxidase subunit VIIc (aka VIIIa)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="8 11" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5 11" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 11" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="4 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="48"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004673"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010514"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00071004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU368123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="OBZ91882.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="67" mass="7246" checksum="BFED9B48644BC79D" modified="2016-11-30" version="1">MISNVLARSAMRASSRQVARSDLYHFSNANGQNIPFDTTNKAALAVKMTLYLGLGFGAPFIAAAWQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NSG3</accession>
    <name>A0A1C7NSG3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Arrestin-like N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_00428</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000009">
        <property type="protein sequence ID" value="OBZ91526.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NSG3"/>
    <dbReference type="InParanoid" id="A0A1C7NSG3"/>
    <dbReference type="OrthoDB" id="2205005at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ91526.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="305" mass="34782" checksum="D0E7153B170BEBF0" modified="2016-11-30" version="1">MRLVGKEQIGDKTFVIVDDIYHLSSRPNDWRMMNNNTYQLGFGFSVPSNIPSSFEDRTASPSKSICYTIQITTSLAPETCWIRPIYFHQSITEESLPKRVFWGVAKLANNQAKWQYELEFPNMFHLDITKSEHVFVRMRSLGQPGIDTCCLIGCQIVQVIHMEGYKCQNQIVAATAKLLRKPNTSWNNPFKLTYEPSELVLPTVEGQKLSIEHYIKFTFAFNDLKVESNMNFEFPVLFMGNLNKSSTHTIVSTRRPMPTVMSSSPSSVSSCNSLKEETRSHDSALDMTVSPDTSINYFALFVKKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NSP6</accession>
    <name>A0A1C7NSP6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Adenylate cyclase</fullName>
            <ecNumber evidence="3">4.6.1.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">ATP pyrophosphate-lyase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="12">Adenylyl cyclase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="17" type="primary">cr-1</name>
        <name evidence="17" type="ORF">A0J61_00254</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP = 3',5'-cyclic AMP + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:15389"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58165"/>
            <dbReference type="EC" id="4.6.1.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the adenylyl cyclase class-3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.6.1.1" evidence="3"/>
    <dbReference type="EMBL" id="LUGH01000005">
        <property type="protein sequence ID" value="OBZ91706.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="FunCoup" id="A0A1C7NSP6">
        <property type="interactions" value="116"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NSP6"/>
    <dbReference type="InParanoid" id="A0A1C7NSP6"/>
    <dbReference type="OrthoDB" id="2021138at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004016">
        <property type="term" value="F:adenylate cyclase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006171">
        <property type="term" value="P:cAMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035556">
        <property type="term" value="P:intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07302">
        <property type="entry name" value="CHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00143">
        <property type="entry name" value="PP2Cc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd17214">
        <property type="entry name" value="RA_CYR1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1230">
        <property type="entry name" value="Nucleotide cyclase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.40.10">
        <property type="entry name" value="PPM-type phosphatase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001054">
        <property type="entry name" value="A/G_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003591">
        <property type="entry name" value="Leu-rich_rpt_typical-subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050216">
        <property type="entry name" value="LRR_domain-containing"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055414">
        <property type="entry name" value="LRR_R13L4/SHOC2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036457">
        <property type="entry name" value="PPM-type-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001932">
        <property type="entry name" value="PPM-type_phosphatase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000159">
        <property type="entry name" value="RA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055071">
        <property type="entry name" value="RA_PHLPP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48051">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48051:SF1">
        <property type="entry name" value="RAS SUPPRESSOR PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00211">
        <property type="entry name" value="Guanylate_cyc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00560">
        <property type="entry name" value="LRR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23598">
        <property type="entry name" value="LRR_14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13855">
        <property type="entry name" value="LRR_8"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00481">
        <property type="entry name" value="PP2C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23010">
        <property type="entry name" value="RA_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00044">
        <property type="entry name" value="CYCc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00364">
        <property type="entry name" value="LRR_BAC"/>
        <property type="match status" value="12"/>
    </dbReference>
    <dbReference type="SMART" id="SM00369">
        <property type="entry name" value="LRR_TYP"/>
        <property type="match status" value="11"/>
    </dbReference>
    <dbReference type="SMART" id="SM00332">
        <property type="entry name" value="PP2Cc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00314">
        <property type="entry name" value="RA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="Nucleotide cyclase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52075">
        <property type="entry name" value="Outer arm dynein light chain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81606">
        <property type="entry name" value="PP2C-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50125">
        <property type="entry name" value="GUANYLATE_CYCLASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51746">
        <property type="entry name" value="PPM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50200">
        <property type="entry name" value="RA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0115">cAMP biosynthesis</keyword>
    <keyword evidence="5" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="10" id="KW-0456">Lyase</keyword>
    <keyword evidence="8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Ras-associating" evidence="15">
        <location>
            <begin position="392"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="domain" description="PPM-type phosphatase" evidence="16">
        <location>
            <begin position="1193"/>
            <end position="1446"/>
        </location>
    </feature>
    <feature type="domain" description="Guanylate cyclase" evidence="14">
        <location>
            <begin position="1515"/>
            <end position="1651"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="44"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="129"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="240"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="926"/>
            <end position="990"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="19"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="44"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="100"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="245"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="265"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="926"/>
            <end position="935"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="942"/>
            <end position="958"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="13">
        <location>
            <begin position="959"/>
            <end position="978"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="979"/>
            <end position="988"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005381"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00021420"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022998"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00032597"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00032637"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50200"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS51746"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="OBZ91706.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="1928" mass="213934" checksum="2525ED5F765F0C65" modified="2016-11-30" version="1">MHSPSWDQSAGRRKETHPPLTQSYTHNSSTGESFLNRVFGYHSGESSRAASPVPSCSSVNQHNRSNTSESTYSSNHTKRDHHSSSNIATGDHTKTRHIRNSSTGNIPISNASPLSIPYMMQRRRSFDGTEANNTLKKPTPTPIPSTSARVANPVASINTTTTNTGMGARSATANQKGINVPRINTAAVPFPRGGRQIGSTLPTPTEISHPQTIVRSNSVEHVQYRVEDQQPKKRHLFRFGKKKSNGTVTTTPTGSSAGSLASGVTGSTAFSSPSSANNSNNMTASDIQRQYYQSQLANERKKSASLNVNANGMDQNFERMDGIVNKEYYRNLSFDAIPPTLIVPDDGSRDNESWAPPDSWGVQPASLMSGAASLMEDDQAEFEDYRMDVPTKNANIKIHRPDRTYNTLHVPLNSTTQEILKRLESKFFLSDIKKYNLVMKRQNVERVLKLYERPLQIQKMLQEQMGYMDQDNIDDISYLVYFQMVPKMAPPLPEDRDFGQNVDLQSRSLSTIPIYXYNHASKIKSLDLSKNILFELPVDFVQRCTNLKQLWLAHNEYTALPAATHHTASLEHLNISGNQLHDLDHARLDKLSQLRTLRAINNKLENIPEAFGSCFQHLTTLFISNNSFTKFPMVICEIVSLAYLDISFNKIQMFPEEIGQLTNLIGLFAIANRITGGLPSSLMNLTKLRELDLRQNLISDLDVVSHLPSLEILLVDYNSTSIVNFEVKSLRQLKMYKNHLTQFNLSCPPGQETSCLTELNLSNCKLSSLPETLFSNTRNLERLVLDSNTLSALPSSIGLLQRLVKLSIQNNNLDSLPSEIGRLTELKILDAQKNNLKMLPKEIWLCASLQTLNCSSNLLESFPPPSSAPLVNGDNMSEMTLACNGDDDMMPIMPPTLNAGQGVIKRLDYSINTAVAPNATFNNHSNAPFNYNLEQSLHPHHSNSQSTQPQTSQQTSLIPSPPPPPPQKSTVPPPPSNFNPPSFFTSPQNHPPPLSLSLRQLFLGDNRLTDDVWSPLLHFSELRTLNLSFNDLYEVPPESLCHQHLYELYLSGNQLTSLPADDIERLQYLRVLAVNGNKLQTLPAEIGKLRKLLVLDVGNNVLKYNIANWPYDWNWNWNLGLKYLNLSGNKRLEIQKTHPDPNNPKDKDLSDFSALTRLRMLGLMDITILGVSIPEEFHDRRVRTSPSEVNSMSYGVADWLGPSDHLSTWDLVMPRFRGKDDECIFALFDGSKHPKSGCPLTKQLNDTLVSQFTKELASTKSDDTIVSAVRRVFLGLEQNLGNSPHLVDKDSGASACVCYISGTKLYVANVGDALAVISRNNGQAFEITQKHIPLNPSEVSRIRAAGGFVSNSGLLNNELNVSRSFGHFHLIPVVNCNPFVSTIDLAENDEFVILASRGLWDRMTYQTAVDIARTEKDDLMAAAQKLRDFAITYGATDNLMVMVIGVGDLFDKREKRFRNNRANNMGPGRGGAGPDVGTDDGLLIKSKRRGKEEVPGDSTLARLEREVAPPVSQLALVFTDIKSSTQFWETQPENMRAAIKIHDAIMRRTLRSVGGYEVKTEGDAFMVCFKNITAALLWCFTVQLQLLEADWPAGILDTEEGREIEKDGVVIYKGLSVRMGIHWGTPVSERNPITQRMDYFGPVVNKASRICNAADGGQICVSSDVIAALRSFPSMFDEDADLQTISSNDEDAFSGTFPVSRDLVQLKQLGFHVVELGERRLKGLETPETLSLVFSKQLLGRIEIDKSEIMAAPQVDPSSDSVVALDDPLITDTGSVVDVSPSMADLVSDVYTDVAPSFAHKKSRTIDANLVCAMSNLAIRLERLTSGHVLSQQNSLVQRHDVAPSNTSILLGNGTPSGLSLMLDRHLREDASDEELLVMMENCVSRVENAVSSLYLQKMGHFANVLEKLGEAIDMDPMHIIKALQILD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NTZ3</accession>
    <name>A0A1C7NTZ3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Ras-related protein Rab-8A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">rab8A</name>
        <name evidence="13" type="ORF">A0J61_00988</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Protein transport. Probably involved in vesicular traffic.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Lipid-anchor</topology>
            <orientation evidence="1">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the small GTPase superfamily. Rab family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000026">
        <property type="protein sequence ID" value="OBZ90964.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NTZ3"/>
    <dbReference type="FunCoup" id="A0A1C7NTZ3">
        <property type="interactions" value="471"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NTZ3"/>
    <dbReference type="InParanoid" id="A0A1C7NTZ3"/>
    <dbReference type="OrthoDB" id="9989112at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01867">
        <property type="entry name" value="Rab8_Rab10_Rab13_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000363">
        <property type="entry name" value="Secretion related GTPase srgA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001806">
        <property type="entry name" value="Small_GTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050305">
        <property type="entry name" value="Small_GTPase_Rab"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47980">
        <property type="entry name" value="LD44762P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00071">
        <property type="entry name" value="Ras"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00449">
        <property type="entry name" value="RASTRNSFRMNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00175">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00176">
        <property type="entry name" value="RAN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00173">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00174">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51419">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51421">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51420">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="9" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-0636">Prenylation</keyword>
    <keyword evidence="6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="188"/>
            <end position="211"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004342"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023289"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00025673"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="OBZ90964.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="211" mass="23449" checksum="99290A74D0B82DD0" modified="2016-11-30" version="1">MATAKSASYDYLIKLLLIGDSGVGKSCLLLRFSDDSFTPSFITTIGIDFKIRTIELDGKRIKLQIWDTAGQERFRTITTAYYRGAMGILLVYDVTDERSFGNVRNWFSNIEQHASEGVNKILIGNKCDMGEKRVISKEQGQALANELGIPFAETSAKANISVEEAFFDLAREIKKRLIDTQQAQQTRQREEVKLDNSAIKAGDSSNSGGCC</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-06-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MTP1</accession>
    <name>A0A1C7MTP1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_11814</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01002529">
        <property type="protein sequence ID" value="OBZ80137.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MTP1"/>
    <dbReference type="InParanoid" id="A0A1C7MTP1"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ80137.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="69" mass="7307" checksum="D7F37820246F77CE" modified="2016-11-30" version="1" fragment="single">VAIVNIPFKLALLVSSETMDFSPSEPTPIDTSLKFISRTSTSSATPVSVSNLLNETDSLDDVASLSYAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MU05</accession>
    <name>A0A1C7MU05_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_11639</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01002286">
        <property type="protein sequence ID" value="OBZ80312.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MU05"/>
    <dbReference type="InParanoid" id="A0A1C7MU05"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="165"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="228"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="176"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="231"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="251"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="271"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ80312.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="302" mass="33401" checksum="3CEA4ABF49E5C6AD" modified="2016-11-30" version="1" fragment="single">DQDEIESNSSGNEDDNEDDVDERENGDFSFNDSHAELLDNDNEENLEPNFEERRALDNDEISAQLNQLDEKILSGAQILSKTINYSDMSLCSEGAHSDTSSSLDSTFYQSMVTANFTEDQAVERQSSVNSFVEGISLFNASPLASSLRLSEPQNILDAQMNKMRRSIQTSSRLSKKGKEPVKSFRTDTDCTDDASGNAVWQHSTLSSDTSIIESANDNAEVDSNFLEKINQESVMPSSEGSTQRTEEHESVQNIDTTTLTEGEVANDSLTAKRKRGNSSKKAIKSKKKPKQGSYGSMEQFIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MVN1</accession>
    <name>A0A1C7MVN1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_11475</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01002080">
        <property type="protein sequence ID" value="OBZ80476.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="InParanoid" id="A0A1C7MVN1"/>
    <dbReference type="OrthoDB" id="2289615at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="438"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ80476.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="438" mass="49389" checksum="840722B96A9589F2" modified="2016-11-30" version="1" fragment="single">MDNGSFSRQSLSGFGNQNSGILVDNGFSIGSSSTGILNDIEDITTDNGISSDVPLSETIHLSDEESDDEELEENQKDDLLDLLSDIQGGNTGAFFLNTIAPLMDILDDSDEDSLDNTADDVMETISDAYPADPFRNVLDFVLIAFFNGSKMNLSXAKIKSIMTMIGLLFKLKERDNTLQLPKTDYILHFNEGKNTRIPFLTPTKHKGTDKKGDEHDFYMNKPSEYLKFLMADPVKGTQLTTLPDHTTYETKSLQQGYKWRTHESFQQPMITLDNGNDVWVTDLVPVNFTGNWDCILVSNFFTKKEDLNSEYITYFKGFPVKYIGDNAGSTFVAIDQNEXTFXISSVYQKVDKVYFARFSYCSNSYNPDYQPIAHNHKALPFWTEQHSALNFKRKKADGSFMKVIVAPIILFSDDTSGNQSKQYNLFDSYLMTPAALSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-06-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MW87</accession>
    <name>A0A1C7MW87_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_10923</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001515">
        <property type="protein sequence ID" value="OBZ81028.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MW87"/>
    <dbReference type="InParanoid" id="A0A1C7MW87"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ81028.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="80" mass="9409" checksum="441FEC8F834A2ACC" modified="2016-11-30" version="1" fragment="single">MPATSTNNSLVYCFCDVCKCSPREDRFIKRSTHRSHKLYRKYNGMAYQDWVKTYNDRIAKSTPPIFIPSKNNTDEPEQTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MWP6</accession>
    <name>A0A1C7MWP6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_10714</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001336">
        <property type="protein sequence ID" value="OBZ81237.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MWP6"/>
    <dbReference type="InParanoid" id="A0A1C7MWP6"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ81237.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="191" mass="21784" checksum="E288092D6CFCD57A" modified="2016-11-30" version="1">MSALSICIYCKKSFATQRDFDLHEEREQCTLKFSLNFLQGNQIDLTPAEPNLPVDTEVADPIDAGSIGSPMAIDLSMVERQGAMISNVITDAIFQDSVEVNWVPKEALTQFQKAVLEFMRLLEEHGTPRQHQRDYINYFDANFAPQFKTDGPFANQFLQSPDTYRRLITKDVTLTVKHHVFLNGCYLFPTN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MX49</accession>
    <name>A0A1C7MX49_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Protein transport protein sec16</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">sec16</name>
        <name evidence="9" type="ORF">A0J61_10468</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5 6">Involved in the initiation of assembly of the COPII coat required for the formation of transport vesicles from the endoplasmic reticulum (ER) and the selection of cargo molecules. Also involved in autophagy.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Endoplasmic reticulum membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the SEC16 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001188">
        <property type="protein sequence ID" value="OBZ81485.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MX49"/>
    <dbReference type="STRING" id="101091.A0A1C7MX49"/>
    <dbReference type="InParanoid" id="A0A1C7MX49"/>
    <dbReference type="OrthoDB" id="8918678at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070971">
        <property type="term" value="C:endoplasmic reticulum exit site"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012507">
        <property type="term" value="C:ER to Golgi transport vesicle membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006914">
        <property type="term" value="P:autophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007030">
        <property type="term" value="P:Golgi organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070973">
        <property type="term" value="P:protein localization to endoplasmic reticulum exit site"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016192">
        <property type="term" value="P:vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd09233">
        <property type="entry name" value="ACE1-Sec16-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.1030">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024340">
        <property type="entry name" value="Sec16_CCD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024298">
        <property type="entry name" value="Sec16_Sec23-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13402">
        <property type="entry name" value="RGPR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13402:SF6">
        <property type="entry name" value="SECRETORY 16, ISOFORM I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12932">
        <property type="entry name" value="Sec16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12931">
        <property type="entry name" value="TPR_Sec16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0072">Autophagy</keyword>
    <keyword evidence="3 6" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="4 6" id="KW-0931">ER-Golgi transport</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Sec16 central conserved" evidence="8">
        <location>
            <begin position="160"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="domain" description="Sec16 Sec23-binding" evidence="7">
        <location>
            <begin position="322"/>
            <end position="633"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="651"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00024687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU364101"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF12931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF12932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OBZ81485.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="651" mass="74076" checksum="C07B74DB86E999D6" modified="2016-11-30" version="1" fragment="single">MNTQHQQQQQYQFDPNVHYYYDEQQQLHYYDPNTNLEYLPYTPQVHQVESRQPTPDVLLPCPEPNCNGENKPTSKFCEECGRALIISRSATPASITRGLANQHISYYPEQNYPVQRPPTAPVYQTPSSYYSQQQHQSMQDLYSLQQQQQQSDHLERAKGCPLITFGFGGKMVVSFPRSVTDYYASTVKSQAGPIQIRRMPKPKEAPLGPVLLDPKMSLKQKKKQITDYIQHRLAQLMEQQNTMATGSVEYHQLTNQWLLWRLVQVMVETDGTVNDKGKMDEAILKIIRPEAQSKEQEDTYFSLPNAIHVDEQDLSDQMLQKIEQLLLEGNRRGAVDYAIQEDLWAHALIISSCVDRQLWQQVIQQFVDRELNATPEVRQKRMFHPACGQNQALRVMYGLFSGSGALAIQEFVKMDVQHFNTAYGLQTVTPTIDWKQLAPWRTTVAMILANRTARDLEALVALGDLMKQQGWIEVAHICYLLSSPMALHSGKDAPQVRLTLLGTETNQKETELSEIVEFVQSIHTSAACMPFLQGYKLAHAWTLADHGFLDEAQRYYEAIDQCIKTWNTSVTANPYLHQGLLQQLNAFGELLEATTGKKGGDPGSWLKPKFQKKAFSSLWGTLEGSLTKFVSGEEVVPQQEPTSRKSTEIMG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MXF0</accession>
    <name>A0A1C7MXF0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_10461</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001186">
        <property type="protein sequence ID" value="OBZ81490.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MXF0"/>
    <dbReference type="InParanoid" id="A0A1C7MXF0"/>
    <dbReference type="OrthoDB" id="2426300at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="197"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="327"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="521"/>
            <end position="610"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="132"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="197"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="219"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="327"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="392"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="447"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="547"/>
            <end position="573"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="592"/>
            <end position="601"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ81490.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="610" mass="70121" checksum="FB15D1E5CBA0E36D" modified="2016-11-30" version="1">MLHDIRYADLTEEQIASIICPRFKNEKILVEEPLVHITNDPVLKKEPKPLVKKEHDRNHDDNMIPFVSRSDSSIIGFTSTDTTEKQVVQTKHTNYSDATTQPDLSFPHASHPKANMDNPKDVVELIQSQIQKLALNEDLLDLKRTVDRMQQERASDLQEHLARLEEQRKRERDMLDQIHATKERLEKAIADGLFEQENQSRATSSKPAHNEPSADPRSNYRHHHSHRQHTHRHRPVPVYEDASRPWRHGYHETQHEPPEFNPYFPDLTSLAFDDFMPPPPPPPLNAHYPLYYHHNQQPDPSPYFSYEELARRRGMMPFDIFMPPHPNPFPPPFAMRPPSPSRGRRTRKRSKSTDTPFYQSDGHRERGSCHTAAEELPPTPYSRSRKSSLHSAKSDLSHEAEQSGTLDPSVGVELHDNPVPFDLSSHHQSQINDPPEKQQRSSLPSAHRSRSGHAQWKIKRASRHEPDAPSSHPPFFDDLPNNRLMEGNDRMMAMMMMAATPSINAAYGIYHASLPPYLPEGRAPYQPSKKGDSPDMLDAPYPEVQDRFSNSHYSRYHSSMPNNGMNQGKSQYGQPFFDPAQTHLLNQREQPSSSSQANHSSIYPTDRIYM</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-06-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MXY0</accession>
    <name>A0A1C7MXY0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_10694</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001322">
        <property type="protein sequence ID" value="OBZ81256.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MXY0"/>
    <dbReference type="InParanoid" id="A0A1C7MXY0"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ81256.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="78" mass="8539" checksum="EBB9050E8436E5CF" modified="2016-11-30" version="1">MEILLEATSFALYGIASFPTKSPAVPSYTAPFLRSSLLHSAHFAVLMMILWNTLFDSVLSNSLSGHPFGPLILRRLSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MXY8</accession>
    <name>A0A1C7MXY8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">A0J61_10685</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the glycosyl hydrolase 5 (cellulase A) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001317">
        <property type="protein sequence ID" value="OBZ81266.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MXY8"/>
    <dbReference type="STRING" id="101091.A0A1C7MXY8"/>
    <dbReference type="InParanoid" id="A0A1C7MXY8"/>
    <dbReference type="OrthoDB" id="9971853at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050295">
        <property type="term" value="F:steryl-beta-glucosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1904462">
        <property type="term" value="P:ergosteryl 3-beta-D-glucoside catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000272">
        <property type="term" value="P:polysaccharide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1180">
        <property type="entry name" value="Golgi alpha-mannosidase II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041036">
        <property type="entry name" value="GH5_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001547">
        <property type="entry name" value="Glyco_hydro_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013780">
        <property type="entry name" value="Glyco_hydro_b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052066">
        <property type="entry name" value="Glycosphingolipid_Hydrolases"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31308">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31308:SF5">
        <property type="entry name" value="ERGOSTERYL-BETA-GLUCOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00150">
        <property type="entry name" value="Cellulase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18564">
        <property type="entry name" value="Glyco_hydro_5_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glycoside hydrolase family 5" evidence="4">
        <location>
            <begin position="61"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="domain" description="Glycoside hydrolase family 5 C-terminal" evidence="5">
        <location>
            <begin position="670"/>
            <end position="744"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF18564"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OBZ81266.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="773" mass="88335" checksum="FFFD727E5F6092AC" modified="2016-11-30" version="1">MELNGRWFIEPKTKRTVLFKGVNVSGGTKLPIGIPSHERNGFWVDYDRKISFVGKPFPLDEADKHLKRFVNLGFNLLRFLVTWEALEHEGPGIYDEDYIDYLIQILKKCQAYNIQVYVDPHQDCWSRHCGGSGHPGWTLSLAGLNPLHFSETNAAIVHNLYPEPEKYPKMIWNTNYQKLAAATMFTLFFAGKTFAPKCVVNGVHVQDYLQNSFIKCFEHLAKAVHYHDLEDTVVVGYDTMNEPGQGYISVPHLDQLSQDDVSFKMGLMPTSFQGMLLGSGIPTEVEYWEFKWDGPKKTDQVLVDPGHLTAWLTETELQQVDTIFGWKRNDTWTAGCIWANHGVWDKETQKLLKPTYFTNHPLAGQPTHFIDYWKDHVTRYAQTLRAIHSSALLFVQPPVLEVPPDMPASLDRLVYAPHWYDGLTLVKKKWCSYNVDFINLNRGKYGTGPLRFLRALRVGEKAIRQCFVDQIQTIKTEGLQHIGQYPCIMGEIGIPYDMETGISSKALSFDYLWHWLESFFVVKQQQNDPSSDIGNPLSSQNKAMDANLNAMEQNLLSYSLWNYTTDNDAQWGDQWNGEDLSIWLSPSDESSTALTVELEASITDQSTMLSTTSSSTVASNDENDKAIRTAVTDKLPWTNPNQAESTDSLQTLLKQYQQHTNRRNVVSIHRPHPRLTAGTPISIRFQSPTDKVKAKFDYTIDYRTPCEGPTEIYLPSCHFPLPPTETNVKATHGHWKIHTCQEHYWVMHWFIDEHFKQEEDGLASLSIEGILAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MY26</accession>
    <name>A0A1C7MY26_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Transposon Tf2-6 polyprotein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">Tf2-6_0</name>
        <name evidence="9" type="ORF">A0J61_10270</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001096">
        <property type="protein sequence ID" value="OBZ81681.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7MY26"/>
    <dbReference type="InParanoid" id="A0A1C7MY26"/>
    <dbReference type="OrthoDB" id="2272258at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016779">
        <property type="term" value="F:nucleotidyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015074">
        <property type="term" value="P:DNA integration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00303">
        <property type="entry name" value="retropepsin_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd09274">
        <property type="entry name" value="RNase_HI_RT_Ty3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01647">
        <property type="entry name" value="RT_LTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.20.370:FF:000001">
        <property type="entry name" value="Retrovirus-related Pol polyprotein from transposon 17.6-like protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.270:FF:000020">
        <property type="entry name" value="Transposon Tf2-6 polyprotein-like Protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.340.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.70.10">
        <property type="entry name" value="Acid Proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.10.10">
        <property type="entry name" value="HIV Type 1 Reverse Transcriptase, subunit A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043502">
        <property type="entry name" value="DNA/RNA_pol_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001584">
        <property type="entry name" value="Integrase_cat-core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041588">
        <property type="entry name" value="Integrase_H2C2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021109">
        <property type="entry name" value="Peptidase_aspartic_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050951">
        <property type="entry name" value="Retrovirus_Pol_polyprotein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000477">
        <property type="entry name" value="RT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041577">
        <property type="entry name" value="RT_RNaseH_2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37984">
        <property type="entry name" value="PROTEIN CBG26694"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37984:SF5">
        <property type="entry name" value="PROTEIN NYNRIN-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17921">
        <property type="entry name" value="Integrase_H2C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17919">
        <property type="entry name" value="RT_RNaseH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00078">
        <property type="entry name" value="RVT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56672">
        <property type="entry name" value="DNA/RNA polymerases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50994">
        <property type="entry name" value="INTEGRASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50878">
        <property type="entry name" value="RT_POL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="3" id="KW-0540">Nuclease</keyword>
    <keyword evidence="2" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Reverse transcriptase" evidence="7">
        <location>
            <begin position="728"/>
            <end position="920"/>
        </location>
    </feature>
    <feature type="domain" description="Integrase catalytic" evidence="8">
        <location>
            <begin position="1267"/>
            <end position="1421"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="204"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="351"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="409"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="212"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="228"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="362"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="1481"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50994"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OBZ81681.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="1481" mass="170258" checksum="1FA0F3AA9A907E0E" modified="2016-11-30" version="1" fragment="single">LYPRGKNSKDYLKMFDVPKFSSKDDPSLWIYQFSKAATMNKWDERTKLYYVDNCFNEKLQMWFMQQNFATWDDFKTPFLNKFTKKVNFDKIASNLINFKMKSNENILEYIERYEELRSKYLLESAKRKRINANMTKGTNDNKPELSISDESPPIQENVTISENGFLNYFIEGVGSNSIKRFLRTEKPETLQEAYHLLKEVYGPEVGENPEKFEDDSDTESLESYESDTETKAKTPKKDISTKNIKTVDKEPGVAELINELKNMTLLIGELVSKKNHKGNTSAKNNKPSCWNCLASDHLTKDCVKPCKLCNKQGHKHYECTLYKKNKPGHNNQAQSESMLIEEVYLSEKRNIGDTDIPDTENSRNFRVSRSGKTVSTPHLKRSVVNHSNPTSMLLPSLESEPYLKSKIDRSKSIQLKPTHPLNPDSKSTGDAGFLQIKREQIIDRLFKNSMHELSLDEISLLSPSARTGFKSRFTKPQSNKKAHVEVTDHINTSAMLGETITNVPKGRSAPRTHGWVNGEPCEVILDGGCTSYIISLSFAKSIGIRELEPFNATVLFGDGVHREPVGLVKNLRLQVGDSPVISIDALCFDVDKYKFIVGREGLHALKIGADWSTHFWYIKRDDGTIPLNTYYTAVINRESVDTEDEVENDEHDSYEDDYIDQDDVEEGYLIMEASDKEEEREHASNNSERFGHLIDRIKDQDNLNKDEKESLIDLLYSYEDCFGTQYEHLSQTNLLKFHVDTGNAKPIYRRPYSFSSFSEKQDLKKDLEEMSFPSRYVPKKTGDKRLISNFRELNASLANSKWFSLVDLLKAFQQIAVEEESIPKLTIATPWGSYSYRCVPFGVLNGPAVFSRCVYLSIQPFLGDFATNYLDDVTIYSKYKSDHLNHIEKFLHRMREVNLKINANKCDFYQQEITLLGFVISEKGIAPSPSKVSKIMEFPRPVNETGVRGFVNLCGFYRRHIPGFADLSVPLNELLKKKNPFNWNDACENAFKAMKKALISATTLMIPDANTEYNLYCDASEVGIGACLAAITDEGEKPVLYLSRKLQPAETRYPTVEKELLAVIYALKKLRKYLLDRKFTLFRDNTAVCYLFNKNEPSQRLQRWVMCTQEFVFDVVHLPSTKNSVAYALSRFPPKLNDDDEDGEDFIEALYDHLMIEEGPNQYEAWLGDLINYFRNCGYEARSLKTKRLSLKYLYENGTLYRKIGLRHVLVPKFYERRRILTEIHDGHGHFGVNASWARLYQSYWWPSCYADIREHVKTCHPCQLFSSTEPNPAVQRVPVNYIFEQFSLDFVGPLPKSTKGNLHILVEAKTVANFLYRHIFCNYGPPTHIPSDNGSAFDNEIVNNFTSLVNVHHQFTSPYRPSTNGRTEQMNGTIVKALKKLSISNPLDWDEHIDAVLYAYRTEAHSVLKVSPYEYMYGIAPNSSRMNPLQLLGRALGMERLVALNDRNVQIDYYNVLKDEYDAKPIVRRKYFESGTMVVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MY62</accession>
    <name>A0A1C7MY62_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Palmitoyltransferase</fullName>
            <ecNumber evidence="10">2.3.1.225</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">Zdhhc20_0</name>
        <name evidence="12" type="ORF">A0J61_10215</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9 10">
            <text>L-cysteinyl-[protein] + hexadecanoyl-CoA = S-hexadecanoyl-L-cysteinyl-[protein] + CoA</text>
            <dbReference type="Rhea" id="RHEA:36683"/>
            <dbReference type="Rhea" id="RHEA-COMP:10131"/>
            <dbReference type="Rhea" id="RHEA-COMP:11032"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57379"/>
            <dbReference type="ChEBI" id="CHEBI:74151"/>
            <dbReference type="EC" id="2.3.1.225"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="10">The DHHC domain is required for palmitoyltransferase activity.</text>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the DHHC palmitoyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.225" evidence="10"/>
    <dbReference type="EMBL" id="LUGH01001075">
        <property type="protein sequence ID" value="OBZ81738.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="FunCoup" id="A0A1C7MY62">
        <property type="interactions" value="252"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7MY62"/>
    <dbReference type="InParanoid" id="A0A1C7MY62"/>
    <dbReference type="OrthoDB" id="9909019at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019706">
        <property type="term" value="F:protein-cysteine S-palmitoyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001594">
        <property type="entry name" value="Palmitoyltrfase_DHHC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039859">
        <property type="entry name" value="PFA4/ZDH16/20/ERF2-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12246">
        <property type="entry name" value="PALMITOYLTRANSFERASE ZDHHC16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01529">
        <property type="entry name" value="DHHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50216">
        <property type="entry name" value="DHHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 10" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="7" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="5 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0564">Palmitate</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 10 12" id="KW-0808">Transferase</keyword>
    <keyword evidence="3 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="52"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="185"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="221"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="domain" description="Palmitoyltransferase DHHC" evidence="11">
        <location>
            <begin position="139"/>
            <end position="258"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00048048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU079119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF01529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="OBZ81738.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="342" mass="39226" checksum="2D3D54A9DA332824" modified="2016-11-30" version="1">MSRPPSPLASKVASTILPFVVYGLLGYTWYVYIFRVCTYLLIKNADRTAQAVVFMIIASFFWIMAVASYTRVLFTSPGKPKNVNLLATEESNQGTFPQLPRYYYSPXLFDWNSYXSRYIDTQDKNESTPVISVCRPDGQSKYCRMCECIKPDRAHHCRECNSCVLKMDHHCPWVSGCVGFGNYKFFFLFVFYTGFYGLWVFVSTLPVVITGIQDMNADLDAQWIALIIIAFIFGFTVCGFSGVHAYYIIKNETTIEHLGDRNNMLRVDFDMSGQNYEVVSVSPLDNLWERSKMENWKSVMGYHPLGWFVPIQRGPGDGTVFPYSDAMFSNIIERALDQRRAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MY78</accession>
    <name>A0A1C7MY78_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_10127</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001044">
        <property type="protein sequence ID" value="OBZ81825.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MY78"/>
    <dbReference type="InParanoid" id="A0A1C7MY78"/>
    <dbReference type="OrthoDB" id="5985073at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd22785">
        <property type="entry name" value="DPBB_MltA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008889357" evidence="1">
        <location>
            <begin position="23"/>
            <end position="225"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ81825.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="225" mass="25037" checksum="2A018A4A57009691" modified="2016-11-30" version="1">MKHTSICTILFVLCSSWMTTMAAPLDKRGIKSCYNNVLITEYWIPKEGDKDMLNDGQLITLSGPKTKALKTVNGKTIAKVSQKTYEKFQMEGTGLLKDGVMVNLDNGKDSFITLDRKKTPYGLGTDSGKLTPWVSVAVNDVKKGTKLYIKKLDGLKLPNGRVHNGCVRVDDEGWSMSGCHIDFFVLQYSAYKDLSNKLPNKLKAVQKNCVIKDYVSSATKKWAVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MYY7</accession>
    <name>A0A1C7MYY7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">A0J61_09960</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000984">
        <property type="protein sequence ID" value="OBZ81992.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MYY7"/>
    <dbReference type="STRING" id="101091.A0A1C7MYY7"/>
    <dbReference type="InParanoid" id="A0A1C7MYY7"/>
    <dbReference type="OrthoDB" id="2123952at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051615">
        <property type="entry name" value="Transcr_Regulatory_Elem"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31313">
        <property type="entry name" value="TY1 ENHANCER ACTIVATOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31313:SF81">
        <property type="entry name" value="TY1 ENHANCER ACTIVATOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0804">Transcription</keyword>
    <keyword evidence="4" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="9">
        <location>
            <begin position="30"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="9">
        <location>
            <begin position="83"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="119"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="187"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="247"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="121"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="247"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="273"/>
            <end position="290"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OBZ81992.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="335" mass="36576" checksum="3011BA758E8F769C" modified="2016-11-30" version="1">MPPSSTCNRKLSNPSPTRNQLVERSSILRGCEPCKSRKQICNGQRPCTHCKARQQDCVYSVVSDHPRSVFTTSTARRLSSGSACETCRRRKTKCDGGSPCSFCASSGIECINNSERRKRSASSASHSPLSTTTTTTSQDSEAIDRIEDRLRRIEKLMTAFTPSPLSQTSGFTKEIHDLKRITAGFRKMSSPHLQRPPVMAPRQHRHSIQGIPHQHQDKITSPSPPLSPSKQSSHSANLMANSMLNLSLSPSSSSTSSSSCIQPSISTPTSSLANPSRSTNDSWKAEWSQSPPIPSLMDQLSNCTFVATAMDYTTVHYPIYPISATSVPKSTSSTQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MZB0</accession>
    <name>A0A1C7MZB0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">RRM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">A0J61_09785</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000937">
        <property type="protein sequence ID" value="OBZ82163.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MZB0"/>
    <dbReference type="STRING" id="101091.A0A1C7MZB0"/>
    <dbReference type="InParanoid" id="A0A1C7MZB0"/>
    <dbReference type="OrthoDB" id="6159137at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006406">
        <property type="term" value="P:mRNA export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00590">
        <property type="entry name" value="RRM_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051229">
        <property type="entry name" value="ALYREF_mRNA_export"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19965">
        <property type="entry name" value="RNA AND EXPORT FACTOR BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19965:SF35">
        <property type="entry name" value="RNA ANNEALING PROTEIN YRA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="4">
        <location>
            <begin position="180"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="23"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="273"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="51"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="273"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="296"/>
            <end position="307"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OBZ82163.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="307" mass="34141" checksum="A51825D848923559" modified="2016-11-30" version="1">MAKGLPDLDRSLDETIRLNKSKVNSRLGRTVPPKLPRSKERDGSLIIKSKSQKEKTNPILNRRDNSHVNKRVNPQITKRTPQVNKQAPQVNKRAAQANKQVPQANKQVPQVSRRDASNIIITKAINTRSTITSGGSIVIKRDMPVKKKETAPKHLEEPPAIQSNPIINTTLSPPVYPTKNIVLICNLDPRATASDVGEACKIFGPVLSCDMLVDPMGRPLCEAEIEFVYPDSAERCVAQLDNNYADGRILRAKLQSTPTMPVVPRYASRTVAASTRVNQSHDANSSPLMAPPQHLYQHHRDPHIRRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MZE3</accession>
    <name>A0A1C7MZE3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_09707</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000916">
        <property type="protein sequence ID" value="OBZ82240.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MZE3"/>
    <dbReference type="STRING" id="101091.A0A1C7MZE3"/>
    <dbReference type="InParanoid" id="A0A1C7MZE3"/>
    <dbReference type="OrthoDB" id="2236538at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="215"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="23"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="30"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="325"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ82240.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="325" mass="35894" checksum="9E9B7002C5AE161E" modified="2016-11-30" version="1" fragment="single">IDTENNRGLLILALEVYGRDPSIDSHAEQRSSTGSTRQSTSVPSFGHNDFEICTMHQTEEKNVSMKLILGAHPFNALVTASARIDDLADQPECGPNTVNFVVPPHSHSKYKLYLDSQSWSDSLALGEKTNLDSIYTRSRLMQLRQLKTRCHEIDTYSSSRSTLFHGYLQQPMTVFTYGKGTTSISSGSLSSRLLATLATSVMRDGESARLAKKSLFFYGSFNFLTTMMILLLATLATSVMRDGESARLAKKSVEKLLSEFTKETKAKVVFLRIIQLFDDNDDIAIIGNSGLNSLAEELATLLAPYISTANKKSVVPSLADHLKSY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-06-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7MZQ3</accession>
    <name>A0A1C7MZQ3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_10055</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001016">
        <property type="protein sequence ID" value="OBZ81896.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7MZQ3"/>
    <dbReference type="InParanoid" id="A0A1C7MZQ3"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="116"/>
            <end position="140"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ81896.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="140" mass="15541" checksum="D8420E2BB7DD7410" modified="2016-11-30" version="1">MTESNKVPLSSIDYSSTNQRESNLDHVLTNPMSPVDTGRPAIESASVLGHEMITHNYHMSNMNNSYNHQQAGLVAVNMNEALYDCPQFYRNNSHNPSVHTANSLLDVPLTPLTRNINAPPRKLSSDLTYAHPDHTSSFGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N0F3</accession>
    <name>A0A1C7N0F3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Protein kinase C</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">PKC1</name>
        <name evidence="7" type="ORF">A0J61_09387</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000838">
        <property type="protein sequence ID" value="OBZ82563.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N0F3"/>
    <dbReference type="STRING" id="101091.A0A1C7N0F3"/>
    <dbReference type="InParanoid" id="A0A1C7N0F3"/>
    <dbReference type="OrthoDB" id="63267at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035556">
        <property type="term" value="P:intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007200">
        <property type="term" value="P:phospholipase C-activating G protein-coupled receptor signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd20822">
        <property type="entry name" value="C1_ScPKC1-like_rpt1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd20823">
        <property type="entry name" value="C1_ScPKC1-like_rpt2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.60.20:FF:000064">
        <property type="entry name" value="Protein kinase C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.60.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.150">
        <property type="entry name" value="C2 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.160">
        <property type="entry name" value="HR1 repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046349">
        <property type="entry name" value="C1-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035892">
        <property type="entry name" value="C2_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011072">
        <property type="entry name" value="HR1_rho-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036274">
        <property type="entry name" value="HR1_rpt_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002219">
        <property type="entry name" value="PKC_DAG/PE"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22968">
        <property type="entry name" value="PROTEIN KINASE C, MU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22968:SF24">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00130">
        <property type="entry name" value="C1_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02185">
        <property type="entry name" value="HR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00109">
        <property type="entry name" value="C1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00742">
        <property type="entry name" value="Hr1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49562">
        <property type="entry name" value="C2 domain (Calcium/lipid-binding domain, CaLB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57889">
        <property type="entry name" value="Cysteine-rich domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46585">
        <property type="entry name" value="HR1 repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51860">
        <property type="entry name" value="REM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00479">
        <property type="entry name" value="ZF_DAG_PE_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50081">
        <property type="entry name" value="ZF_DAG_PE_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="REM-1" evidence="6">
        <location>
            <begin position="1"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="domain" description="Phorbol-ester/DAG-type" evidence="5">
        <location>
            <begin position="298"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="domain" description="Phorbol-ester/DAG-type" evidence="5">
        <location>
            <begin position="364"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="431"/>
            <end position="583"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="442"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="474"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="487"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="523"/>
            <end position="532"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="535"/>
            <end position="550"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="572"/>
            <end position="583"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01207"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50081"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51860"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OBZ82563.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="583" mass="66010" checksum="34474441E1E2D49B" modified="2016-11-30" version="1">MSETPYNKPKVSLKLHELEYKLDVEKTVLKGIRGMVDVLERTASTDRKSRSEVQDKMSESQEKLTLLNSALRKYKSLYIGEGGDEEDYELETPPSARLPPGFRRPVTGKLQLEILEAMELAHAPTRMIRSPATVVMVKIDNQVVFRSRPARNDKWSELCETHVNKASEIEIGIYDQSPERSLPIGFFWLKITDITEGLRKRKMMPPSQWMLAEDAQKLHHDGQLEKREDSSTAIQPIPPVQVSQNEAGIEAWFDVEPVGKLALRLNFVRAEGNRRPMDKLGRAGAVRQRREEVIEVNGHGFVENRFYNVMKCALCQEFFVNSGYQCEDCEYTCHKKCSSKVVTKCPKNSTDNDSDEDKLNHNIPHRFEPITNIGANWCCHCGYMLPLGSRGSKRCSECDITAHTKCEGYVPDFCGLSMEMANQMLAEIKAAAKRKTNDTKSSRTSKQEPSTPSSQEAPLPPQPEEITVAPVVHDEEDNERDDEEEQLSLQLSSTSLLPPKSPVAVPQTPPTMYNNPIQPPSTQPYYSPNQAAMSMPQPNRMYPPQQQQRPPSLPTHQPPYGYNPANVDPRYQQQQQQQIQASV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N0H9</accession>
    <name>A0A1C7N0H9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Protein ral2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">ral2_2</name>
        <name evidence="5" type="ORF">A0J61_09810</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000944">
        <property type="protein sequence ID" value="OBZ82139.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N0H9"/>
    <dbReference type="FunCoup" id="A0A1C7N0H9">
        <property type="interactions" value="138"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N0H9"/>
    <dbReference type="InParanoid" id="A0A1C7N0H9"/>
    <dbReference type="OrthoDB" id="10001928at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045454">
        <property type="term" value="P:cell redox homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.80">
        <property type="entry name" value="Kelch-type beta propeller"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000210">
        <property type="entry name" value="BTB/POZ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015915">
        <property type="entry name" value="Kelch-typ_b-propeller"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43503">
        <property type="entry name" value="MCG48959-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43503:SF2">
        <property type="entry name" value="NEGATIVE REGULATOR OF SPORULATION MDS3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24681">
        <property type="entry name" value="Kelch_KLHDC2_KLHL20_DRC7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00225">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117281">
        <property type="entry name" value="Kelch motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54695">
        <property type="entry name" value="POZ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0880">Kelch repeat</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="BTB" evidence="4">
        <location>
            <begin position="419"/>
            <end position="624"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="468"/>
            <end position="544"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="662"/>
            <end position="816"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="497"/>
            <end position="511"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="513"/>
            <end position="544"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="669"/>
            <end position="692"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="706"/>
            <end position="737"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="748"/>
            <end position="770"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="771"/>
            <end position="786"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OBZ82139.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="830" mass="92705" checksum="B7AD4AB3D2EDD74D" modified="2016-11-30" version="1">MAMSSSMQMQSISGIITQIHVTTGEVPPALVGASVNVIGDKVYVFAGRLATSRTMTNYLYILDLTTLSWTQHIPPPDSDRPPKARYFHSASVHNDQLIIFGGMGHSSRMSSDSNGLLVLDDIAIFDIQTMCWTQPTIPPSLYSPQARYAHLSAITEDRLVVMGGQDLENNYLDQINVLNLQTMEWEQATLFEKHVGAYRSIAVTAPTSARFPIQQEEAATPAAEELSESPFDQQAMSVQSSTEDGNPIYLYTNYNFSDVKRELQLIYTSSATKSPQAIIEEHSNLMNGSVMPPGLRFPTGYTLGNHLILAGTYLSPQTQSYTIWSLDLTKLTWSRIETGSVFSSGSWNRGVLHEASNRLLVFGNSNRNLLDDYNHRQVNFEHLAMVDLEAFGVYTLPKPTCSSLAQEMGLRLLNEPAVSDFYIITQDNISIPVNSAVLGQRWPYFARLMKENVVQQTKRFKESILDEKIVEEEEEEEDTKKEPTTEQEAAATKQEEAATEQEVATEEEATEQEPTKEGAAEQEPTKEEATEQEPTKEEVIKPIEEVTEESIEEEEQFSMIKSHYMSFPYPHTVVIALLQFIYTDNLLTAQQYQPQILSQLLLLADMYDIPRLSQLATHALHQMLNMSTAPLIFETAALSHQTSLQIRALKMMIAAKKMIQQQQQQQQQSRSRTVSTPTTMNSLEQTPVSPTASLSSSSYHLDKENTPITASPTLQSFRSRRPSASQNRVHGPSTYSLLPQPQPQPYRTSTLTNLSSPLTSPTAATSYSLPNNSPSAKLHSQSEVTFSQRQRRSSSPPKPNTESKSTPKETKKKKKAFLEAFGKLSSSISK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N0K0</accession>
    <name>A0A1C7N0K0_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_09756</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000929">
        <property type="protein sequence ID" value="OBZ82196.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N0K0"/>
    <dbReference type="InParanoid" id="A0A1C7N0K0"/>
    <dbReference type="OrthoDB" id="2265579at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ82196.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="197" mass="22793" checksum="6E75427ACDF37073" modified="2016-11-30" version="1">MHARNPQLTFDQIKERKERGISVFIPAIKSALIQEAKYNHSFSKAEILYGYLTEAVVHRTDPERHRGDINCLRRAIGVMTRYAPNPDKALFYAYHFFAEFGPPFRTPSSEMIVLTNLLFAYSLAGTEEAMRNAVDIIRLAIEIGVFRIDPKGYDDVLAEREQFKHPLDVFETICQRPLQHQRLMFNADKSDLIPVHR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N0T9</accession>
    <name>A0A1C7N0T9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">CCHC-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_09255</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000809">
        <property type="protein sequence ID" value="OBZ82692.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N0T9"/>
    <dbReference type="InParanoid" id="A0A1C7N0T9"/>
    <dbReference type="OrthoDB" id="2280262at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.60.10">
        <property type="entry name" value="Zinc finger, CCHC-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036875">
        <property type="entry name" value="Znf_CCHC_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57756">
        <property type="entry name" value="Retrovirus zinc finger-like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="290"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="290"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="304"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="321"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ82692.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="321" mass="35715" checksum="A5ADDC2DE0B02A3A" modified="2016-11-30" version="1" fragment="single">MSAPGEIPWAKVAERGHQLRVPLSSRSHHQDSTVKYVPEVISQTPDFETELLNRRAASIVHQALTTGLVIFKFPPGTFANHLEAYEAIDKELGPVEGFQYLSGFTPNPSKVDMLIEARFESTESRDHAIQTGLVVGDVTFRCTASSSGTSPNAFVHVALNVIIIPPKAELLLGMSFFDGQISFVIDTQTPTLKAADGQAIPVWDLTRQLYLSYWDRHAPASFKGAAPVCFYCRQAKYFRRDYPKLKDQVCFGCGVKGHTRRFCGRLKGKRVESVTEEDVLDEYIQLRNQAKETVRTRPQRASDESQQPTIHSSIPDGTSAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N0Y6</accession>
    <name>A0A1C7N0Y6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">ER-derived vesicles protein ERV14</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">ERV14_0</name>
        <name evidence="7" type="ORF">A0J61_09296</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the cornichon family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000818">
        <property type="protein sequence ID" value="OBZ82658.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N0Y6"/>
    <dbReference type="FunCoup" id="A0A1C7N0Y6">
        <property type="interactions" value="598"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N0Y6"/>
    <dbReference type="InParanoid" id="A0A1C7N0Y6"/>
    <dbReference type="OrthoDB" id="434393at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016192">
        <property type="term" value="P:vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003377">
        <property type="entry name" value="Cornichon"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033466">
        <property type="entry name" value="Cornichon_conserved"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12290">
        <property type="entry name" value="CORNICHON-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03311">
        <property type="entry name" value="Cornichon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01398">
        <property type="entry name" value="Cornichon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01340">
        <property type="entry name" value="CORNICHON"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="56"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="112"/>
            <end position="134"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010095"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OBZ82658.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="136" mass="15613" checksum="633C98400B204F00" modified="2016-11-30" version="1">MMPGEAMLFLFAVIMSALLLFAMVILFSDLECDYINPIDLCNKLNQFVLPEMGAHAFLFLMFLLNGSWIALALNLPLLAYNVNKVMNGRHMYDATEIFRTLPQQKKECFIKLGFYLLCFFYFLYRMIVALIAAADA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-06-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N1G8</accession>
    <name>A0A1C7N1G8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_10748</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01001363">
        <property type="protein sequence ID" value="OBZ81204.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N1G8"/>
    <dbReference type="InParanoid" id="A0A1C7N1G8"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="41"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ81204.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="41" mass="5085" checksum="67061308CDB3902E" modified="2016-11-30" version="1" fragment="single">MDDREKKEEEILDVEENRRRLKEVLETVLAFDFPLHELDRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N1K7</accession>
    <name>A0A1C7N1K7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="6">LIM domain-containing protein E</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">limE</name>
        <name evidence="6" type="ORF">A0J61_09060</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000764">
        <property type="protein sequence ID" value="OBZ82891.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N1K7"/>
    <dbReference type="STRING" id="101091.A0A1C7N1K7"/>
    <dbReference type="InParanoid" id="A0A1C7N1K7"/>
    <dbReference type="OrthoDB" id="8062037at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.110.10">
        <property type="entry name" value="Cysteine Rich Protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001781">
        <property type="entry name" value="Znf_LIM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24206">
        <property type="entry name" value="OS06G0237300 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00412">
        <property type="entry name" value="LIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00132">
        <property type="entry name" value="LIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57716">
        <property type="entry name" value="Glucocorticoid receptor-like (DNA-binding domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50023">
        <property type="entry name" value="LIM_DOMAIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4" id="KW-0440">LIM domain</keyword>
    <keyword evidence="1 4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="LIM zinc-binding" evidence="5">
        <location>
            <begin position="24"/>
            <end position="84"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023038"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OBZ82891.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="85" mass="9930" checksum="25291615B53E144B" modified="2016-11-30" version="1">MIMLSLIAKPKPKTIYTPYNMESNKCHICSKTVYYSEKIEANNRAYHKLCFKCQDQGCRLTLANFHYHHGNLFCPKHVPKLKAIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N1L1</accession>
    <name>A0A1C7N1L1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glycerol-3-phosphate O-acyltransferase 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">GPT2_0</name>
        <name evidence="3" type="ORF">A0J61_09072</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000767">
        <property type="protein sequence ID" value="OBZ82878.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N1L1"/>
    <dbReference type="InParanoid" id="A0A1C7N1L1"/>
    <dbReference type="OrthoDB" id="5567124at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004366">
        <property type="term" value="F:glycerol-3-phosphate O-acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016287">
        <property type="term" value="F:glycerone-phosphate O-acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008654">
        <property type="term" value="P:phospholipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07992">
        <property type="entry name" value="LPLAT_AAK14816-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052744">
        <property type="entry name" value="GPAT/DAPAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002123">
        <property type="entry name" value="Plipid/glycerol_acylTrfase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31605">
        <property type="entry name" value="GLYCEROL-3-PHOSPHATE O-ACYLTRANSFERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31605:SF0">
        <property type="entry name" value="GLYCEROL-3-PHOSPHATE O-ACYLTRANSFERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01553">
        <property type="entry name" value="Acyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00563">
        <property type="entry name" value="PlsC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69593">
        <property type="entry name" value="Glycerol-3-phosphate (1)-acyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="321"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="354"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="380"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="domain" description="Phospholipid/glycerol acyltransferase" evidence="2">
        <location>
            <begin position="40"/>
            <end position="167"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ82878.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="500" mass="57018" checksum="B59EA94C907BD432" modified="2016-11-30" version="1">MPFGFYHEVVCQVSRSALWSFFSDIXLEDVENVPSDSRPLIVAATHHNMIVDPAVLSVTFPRQRRLHYWAKDSMFKNPYAAAFLNDCGVVPVDRTTKNNAKLYAATFEVLKLGEAVAVFPEGTSHTLPRLGAFKDGTSFAALEYAKINQEQNLNMPAPILPVGIVYPEKSKYRSAVIVKYGKPIAVEPLLSLYLEDPKKAAKQLTKLTEEAIEKITVNSPDWDSKHSADMARWLLFPGEHGTMKDYISVTQSLINSMNALAEKDIEIARLQKSLIAYKLELESLSLKDSQIAKYNEKEITAITTTVQLLKRTAASLIDLPLFLPGLVAHMPLYVAGYLAGHFEIYEEVRAQNKIFFGMLLVPVIYLITFLWAWYSLFDGTMMGFFVALATLGVFVWYHVTSIDERYDNFKDLLGRWRLFDAVVLGRGMWRRKERILHLKQLRSENLASVRKMITTYKSTNDDVHVVWLALRQRVRQFGDVSKLRLKKKALAKQYEWCFEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N1S9</accession>
    <name>A0A1C7N1S9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">AADAT_1</name>
        <name evidence="7" type="ORF">A0J61_09012</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000754">
        <property type="protein sequence ID" value="OBZ82938.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N1S9"/>
    <dbReference type="FunCoup" id="A0A1C7N1S9">
        <property type="interactions" value="162"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N1S9"/>
    <dbReference type="InParanoid" id="A0A1C7N1S9"/>
    <dbReference type="OrthoDB" id="691673at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047536">
        <property type="term" value="F:2-aminoadipate transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047315">
        <property type="term" value="F:kynurenine-glyoxylate transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901605">
        <property type="term" value="P:alpha-amino acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00609">
        <property type="entry name" value="AAT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.640.10:FF:000071">
        <property type="entry name" value="Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.1150.10:FF:000166">
        <property type="entry name" value="Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004839">
        <property type="entry name" value="Aminotransferase_I/II_large"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050859">
        <property type="entry name" value="Class-I_PLP-dep_aminotransf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42790">
        <property type="entry name" value="AMINOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42790:SF19">
        <property type="entry name" value="KYNURENINE_ALPHA-AMINOADIPATE AMINOTRANSFERASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00155">
        <property type="entry name" value="Aminotran_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="5" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotransferase class I/classII large" evidence="6">
        <location>
            <begin position="70"/>
            <end position="402"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OBZ82938.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="413" mass="46195" checksum="C4A1CDA83CABBC17" modified="2016-11-30" version="1">MDYQAFISERSKARKPSAIRALSPYLHQKDMISLGAGQPNPSTFPFAGMSITLKSGETLSIDSELFSRSLSYDLTPGLPHLNNWLRELQIREHKPPVDFDLSIGCGSQDLLTKAFEMLLNDGDAIMVENPSYTGCLSFLKTLRCDLAAVATDAYGIVPDSLESLLSNWPQDSPQPRPRVLYTIPSGGNPTGATATLERKQAVYAICQRFNVLIIEDDAYYYLQFQSPRIPSYLSLDQDGRVLRCDSMSKILSAGLRLGWITGPAALLERINMHTMVTNLQPSGIPQVMAYQLLSQWTHQGFFEHVEHVAQFYREKRDDFVDCLDRHLKGRAEWVVPQAGMFVWLKLVGVTDSYDLVMTKAVKENVLAIPGVAFLPEGTQSEYVRVSYSNVSKSDMDEALARLARVVDQEVSKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N2B0</accession>
    <name>A0A1C7N2B0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">U1 small nuclear ribonucleoprotein 70 kDa</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">RNU1</name>
        <name evidence="11" type="ORF">A0J61_08710</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus speckle</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
            <location evidence="2">Nucleoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000697">
        <property type="protein sequence ID" value="OBZ83242.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N2B0"/>
    <dbReference type="FunCoup" id="A0A1C7N2B0">
        <property type="interactions" value="258"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N2B0"/>
    <dbReference type="InParanoid" id="A0A1C7N2B0"/>
    <dbReference type="OrthoDB" id="4207594at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016607">
        <property type="term" value="C:nuclear speck"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071011">
        <property type="term" value="C:precatalytic spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005685">
        <property type="term" value="C:U1 snRNP"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="EnsemblFungi"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071004">
        <property type="term" value="C:U2-type prespliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030619">
        <property type="term" value="F:U1 snRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd12236">
        <property type="entry name" value="RRM_snRNP70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.330:FF:001585">
        <property type="entry name" value="U1 small nuclear ribonucleoprotein 70 kDa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034143">
        <property type="entry name" value="snRNP70_RRM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051183">
        <property type="entry name" value="U1_U11-U12_snRNP_70-35kDa"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022023">
        <property type="entry name" value="U1snRNP70_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13952">
        <property type="entry name" value="U1 SMALL NUCLEAR RIBONUCLEOPROTEIN 70 KD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13952:SF5">
        <property type="entry name" value="U1 SMALL NUCLEAR RIBONUCLEOPROTEIN 70 KDA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12220">
        <property type="entry name" value="U1snRNP70_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 11" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4 7" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="10">
        <location>
            <begin position="100"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="184"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="58"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="200"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="212"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="9">
        <location>
            <begin position="237"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="9">
        <location>
            <begin position="257"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="268"/>
            <end position="283"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00016996"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="OBZ83242.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="283" mass="32795" checksum="146F44D04D6DCFAD" modified="2016-11-30" version="1">MTDKLPPNLLKLFAPRPPLPYLPQLDKDPEKRVGCIVDGIASYVDQLRNYDPDYVPWKTLEEKRKEKAEAKRKQAEANLKEKLAEYDPEKDPNIDGDPFNTLFVTHLSPELTESDLAREFELYGQIKKIRLVRDQEGKSRCYAFIEFEREKDMRAAYKDADGLKILGRRILVDVERARTVKGWKPRRLGGGLGGREQQKKSSAIQHHPTSQSRDRYHDRDRGHRGYGYNRRDDDNRKRSRMRSRSRSPRGYNSSRYGNGGGGGGGGGGRRDRSRDRMGRRDRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N2E9</accession>
    <name>A0A1C7N2E9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_08792</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000712">
        <property type="protein sequence ID" value="OBZ83158.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N2E9"/>
    <dbReference type="STRING" id="101091.A0A1C7N2E9"/>
    <dbReference type="InParanoid" id="A0A1C7N2E9"/>
    <dbReference type="OrthoDB" id="2221171at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ83158.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="93" mass="10325" checksum="2B250F7794345AFF" modified="2016-11-30" version="1" fragment="single">STKAVKKGSRIDKVKKHANWSLNTSTFEDYYYKPVGQLNESTKIQNAIFSNDTENITTTSESEAEATRIVIGMTANPQVAEAKDEEVVVTRPC</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N2F5</accession>
    <name>A0A1C7N2F5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Rab-GAP TBC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_09077</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000768">
        <property type="protein sequence ID" value="OBZ82876.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N2F5"/>
    <dbReference type="STRING" id="101091.A0A1C7N2F5"/>
    <dbReference type="InParanoid" id="A0A1C7N2F5"/>
    <dbReference type="OrthoDB" id="295078at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031267">
        <property type="term" value="F:small GTPase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.80">
        <property type="entry name" value="Ypt/Rab-GAP domain of gyp1p, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000195">
        <property type="entry name" value="Rab-GAP-TBC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035969">
        <property type="entry name" value="Rab-GAP_TBC_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050302">
        <property type="entry name" value="Rab_GAP_TBC_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47219:SF9">
        <property type="entry name" value="GTPASE ACTIVATING PROTEIN AND CENTROSOME-ASSOCIATED, ISOFORM B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47219">
        <property type="entry name" value="RAB GTPASE-ACTIVATING PROTEIN 1-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23436">
        <property type="entry name" value="RabGap-TBC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47923">
        <property type="entry name" value="Ypt/Rab-GAP domain of gyp1p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rab-GAP TBC" evidence="1">
        <location>
            <begin position="47"/>
            <end position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF23436"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ82876.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="105" mass="12038" checksum="5D858F73F495D993" modified="2016-11-30" version="1">MQLLKEEAVYEEAIACDLPKATFNQHDYFIDGDEPDALFNAIKASSLNMPEEEAFCIPVQLTNKYNLRGHFLPQSELLSQRLYQLEGLVADHLPHIQRHFEAHGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N2W6</accession>
    <name>A0A1C7N2W6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">THO complex subunit 2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">tho2</name>
        <name evidence="9" type="ORF">A0J61_08575</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the THOC2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000673">
        <property type="protein sequence ID" value="OBZ83377.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="FunCoup" id="A0A1C7N2W6">
        <property type="interactions" value="815"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N2W6"/>
    <dbReference type="InParanoid" id="A0A1C7N2W6"/>
    <dbReference type="OrthoDB" id="29024at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000445">
        <property type="term" value="C:THO complex part of transcription export complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006406">
        <property type="term" value="P:mRNA export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040007">
        <property type="entry name" value="Tho2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021418">
        <property type="entry name" value="THO_THOC2_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021726">
        <property type="entry name" value="THO_THOC2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032302">
        <property type="entry name" value="THOC2_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21597:SF0">
        <property type="entry name" value="THO COMPLEX SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21597">
        <property type="entry name" value="THO2 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11262">
        <property type="entry name" value="Tho2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11732">
        <property type="entry name" value="Thoc2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16134">
        <property type="entry name" value="THOC2_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="THO complex subunit 2 N-terminal" evidence="8">
        <location>
            <begin position="45"/>
            <end position="666"/>
        </location>
    </feature>
    <feature type="domain" description="THO complex subunitTHOC2 N-terminal" evidence="7">
        <location>
            <begin position="668"/>
            <end position="748"/>
        </location>
    </feature>
    <feature type="domain" description="THO complex subunitTHOC2 C-terminal" evidence="6">
        <location>
            <begin position="970"/>
            <end position="1272"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="367"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1294"/>
            <end position="1646"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="382"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="1313"/>
            <end position="1337"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="1379"/>
            <end position="1406"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="1448"/>
            <end position="1468"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="1470"/>
            <end position="1487"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="1496"/>
            <end position="1512"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="1513"/>
            <end position="1542"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="1544"/>
            <end position="1560"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="1561"/>
            <end position="1639"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00019596"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF11262"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF11732"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF16134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OBZ83377.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="1646" mass="189830" checksum="58BA560D621ACA1B" modified="2016-11-30" version="1">MSLNSNEFTHDVVVQDEIDRMKAAAPDYRIGTTCEFRTIISNACRDTYFGRRSIANFAEVAVPMIKQQQEFEAFEIPVKDLYFNSIKTWESQWEALRESQTQSPEKALKYKKSTENLAGMINALLASEVITTGDCKIHLTVQLMFECGIINNVKLFERRLVRLNTAMLYKQDKYNLVREVGEGYASLFNELTNASIDNARDSKGKLESTPMERIPQFLKTITSHMGVFHLDPNRVLDIILDLFIRQLKVNHKFWIALIKESEWVKSLVHTDLNGELVTNPSPIMAQLFGFRFHSYHNEDTEDTPKEIYFAIAILLANDLILLGDILPYLYPYHEGMYIEKKEYIEHMNKEINTNSGGQLATYGALGETEGSTVRMKRQKQEDEAEEKEEEEETKKKYSQNDVVELVRALLSIGDLKHAHMILAEYEKLVDLYPELAYDIYRLCSIVLDPAYEAFVPEETKSLYRHFHDCADQSQIKTALSTQDDPNPKIPDQTKLKRVLVFDALLDNTKDIIKRERYVFFYKDTRDGLDLCTEPEHLMTRFLPLARLAGYKTYLCTELVQKVMLIVGSLVERESEFPNSRTYCTNLLREFLLPSIAFSQGNPGTMASVWEILCRFTFQERYALYGEWHADFYKKTIETKLLKVRTERSIREVMRCVNKNNVRPSGRDLGKLAHSNPTLVFHHMLDQVQQFENLAPLMAEACRYYGDFAYDVLGFVLTEKWTGSQGPGRTVKAKEKDDGFAHLWFRSLAIFTGMLFKKQDMEATPLLRYLACRLRYDDSVSDLHLLNEFVTKMGGIEILASALTDDQIAAASCSETIKNEAFLPVSSDNRRASRRVLSRLKESLRKNNIGFEILVLLYRLDEVCSAEVGVPAAVRCHKLDHVHQSQIQYFELLTSLFEGDDYNAIIPEPESLIKDYQLPLDVVMNFTRPKTQHVIRSSIQEPVVEGAIWTPFQSLCQAITPALPEPPLGTIFSAEFYVVFWQLTLYDIYCPEEPYESAIKRETDVIRKCQDTRSQFYLNNRPSVVLKTQRQAQLRLDQLREDLTKHKAHVEKMMSVLKESKSRWFPSLNQRQAQISSIMQYCLLPRSRQSEVDAAFCYEFTMLMHRINTPNFSSLTLFDKMLSDNLPASFLAFSEYETTVYSRFIFKALSRMQKWHADEKLYAKEAHGNNLIGFQKNWNSTPTPIAKEDLLSFADFQRVLHKWHFKSDLVIEQALKSGEVVVMKNAFMVLRQFAPCFPAVADHGNSIMKIVKKLAEEDERGNIKVLARSYMGLIAKYKTKWISKEAFLGLKQPSPPVEIKIVPTGNTKETNSSSKDKSSNHHDSSRREESSSKKRDESAAVESKSSRPVSPSNTRRNDDTGRSKSSQRATSPSKSSPPPTDRKRTRDTEPSSSSRGEKMARIEENGTSRHHHRSSSRRESPRESVNSSSRLNTPVRNENRSSRNDPAPSSATATATVVVAQTTQTTSRSSTHRESSRVVDERSSRGRAVESNSSNRAAPSSTNQNTAANSSSKRPVDADVRDRVREERPEKRRDLREESRTVRESANSAPTAAAPTSSTSRSRLDESRRGEDRARERRVDDRRADDRRLDDRRMDDRRMDERRMDERRIDDRRLDDRRMDDRRMDDRRLDDRRRERDRDRDHRHRRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N3F4</accession>
    <name>A0A1C7N3F4_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_08780</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000710">
        <property type="protein sequence ID" value="OBZ83169.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N3F4"/>
    <dbReference type="InParanoid" id="A0A1C7N3F4"/>
    <dbReference type="OrthoDB" id="2418221at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="31"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="67"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="34"/>
            <end position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ83169.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="123" mass="13443" checksum="B484D27B8D14945B" modified="2016-11-30" version="1">MPFRCKCGRTFEKTDTFASHTSSCAPFHHRRMSDTTQLSTNSMPVPSTPHRQSLPFVNPSFSRGLLSTSPQSVSSTQSILDTPSSDLSSSAPSNTFFMPTALSLQNAFEGARRRSMSYGSSLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N3F7</accession>
    <name>A0A1C7N3F7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_08342</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000632">
        <property type="protein sequence ID" value="OBZ83611.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N3F7"/>
    <dbReference type="STRING" id="101091.A0A1C7N3F7"/>
    <dbReference type="InParanoid" id="A0A1C7N3F7"/>
    <dbReference type="OrthoDB" id="336240at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="12"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ83611.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="371" mass="42017" checksum="7264B6E45B7F6B44" modified="2016-11-30" version="1">MKRSRPSRAEASSNWRSSNYSSNPASNPSREMGREHVARRQRTLDMWLNADQMNMNCPEHLSQGQSANMGIDSFNQNFLSVNNEQVNQNEASVFSFAPEINGHNALNNHISSAQTSWNPFNSRTISPFKSLVQQNTETADLMEVEPSIWPGNTQSNHSTTVQAFSSFSDSMQMSRNTMSIENEENCPIYRPYNVIKITNFPFHVGISDIKSIFNSNAYFSLPNEADLVQCVHVMMDIKTGKTMGTAFVEVICNDVDNIVRCLGSFNFRDNQAFRNCKFTPSSYDEICSQLFQNWSGQFRNGMAFPNAPTSNIRDMMMAGSKKKSFFISGQELQALVNICQKFKANFNRRSTKCLDTNPVESYLSTLQRGSW</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-09-13" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N3N7</accession>
    <name>A0A1C7N3N7_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_08701</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000695">
        <property type="protein sequence ID" value="OBZ83249.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N3N7"/>
    <dbReference type="InParanoid" id="A0A1C7N3N7"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ83249.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="280" mass="32446" checksum="53E10D9139866408" modified="2016-11-30" version="1">MFQQLASYVHTMDHVILKIGEIPNRIGLFQALQRFQWQGHTDTQIDGFMFEHDSSKSKYSVLDSRCNVDEFQFTHENIAYLNQLDEFNFDISQYDSESRISDVHHQILSHCKRLRKLSIDFSSLEYFEIPGLPVTSLSLGPYGTSPELLSQFSYMLPCLEEVEILQFFHDDHYEEPTGGFSIEILLPVTSLAKLKIEMIDCVDINVFYLQLSQSGIESTHQLCGTTFYETEMNICEEREPSNKAANLKLTCEAIQQLEIICHLERYPPARTHFIYSSDRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N3Q7</accession>
    <name>A0A1C7N3Q7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transposon TX1 uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">YTX2_8</name>
        <name evidence="2" type="ORF">A0J61_08199</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000609">
        <property type="protein sequence ID" value="OBZ83752.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="InParanoid" id="A0A1C7N3Q7"/>
    <dbReference type="OrthoDB" id="2288491at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.10.10">
        <property type="entry name" value="Endonuclease/exonuclease/phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036691">
        <property type="entry name" value="Endo/exonu/phosph_ase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005135">
        <property type="entry name" value="Endo/exonuclease/phosphatase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03372">
        <property type="entry name" value="Exo_endo_phos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56219">
        <property type="entry name" value="DNase I-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Endonuclease/exonuclease/phosphatase" evidence="1">
        <location>
            <begin position="22"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="496"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03372"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ83752.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="496" mass="56870" checksum="66F01874B50AA02B" modified="2016-11-30" version="1" fragment="single">MHPSTFDPSSPSGTTNHFRIGSINCRSLAKQHNPSQRSNFIRYLRDLQYDILCLQETHADLPNVQDVLNTQFRAHSSIWTKHCGVVSLNPLIQITPDFITRDQRVIACLVHHINHLFPPVHVLNIYFPAQLAERRPFITSLIRLPLLQQYDFLHSGADTQNSFLNVSPLLLLGDFNFQLADYSGRDIDPTALDRLHPQHHWYHFLNSSFVECSQHSDPPSPILPTFRRGRSKSTIDYIYASPYLYQHLHSSTVDFVNPAWTDHAFLGCTFAFSSPSQGPXLWRANPRLSQDPTFQQLLTNELDDYHEFIQTTHTPPSXQQQWDDIKKLVQTIARKSGRRKTSAHQRLLARLQRKRNKFLREYKLTSILPLRLETVEKQIGILQQDRVETLALRAGKMWRENGEKAAGYLKSTITSRTIKRNIPVLQHPQTNQLCHSVADLHSATTTFYKSLYTPSPIDLTSATTLTATIPTSQQLRPSQQTELLLPFTLLELQEGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N442</accession>
    <name>A0A1C7N442_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Epidermal growth factor receptor substrate 15-like 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">EPS15L1_0</name>
        <name evidence="5" type="ORF">A0J61_08096</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000594">
        <property type="protein sequence ID" value="OBZ83850.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N442"/>
    <dbReference type="STRING" id="101091.A0A1C7N442"/>
    <dbReference type="InParanoid" id="A0A1C7N442"/>
    <dbReference type="OrthoDB" id="524326at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006897">
        <property type="term" value="P:endocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016197">
        <property type="term" value="P:endosomal transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00052">
        <property type="entry name" value="EH"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000261">
        <property type="entry name" value="EH_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11216:SF170">
        <property type="entry name" value="DYNAMIN ASSOCIATED PROTEIN 160, ISOFORM D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11216">
        <property type="entry name" value="EH DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12763">
        <property type="entry name" value="EH"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00054">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00027">
        <property type="entry name" value="EH"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50031">
        <property type="entry name" value="EH"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0675">Receptor</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="EH" evidence="3">
        <location>
            <begin position="1"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="4">
        <location>
            <begin position="9"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="domain" description="EH" evidence="3">
        <location>
            <begin position="76"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="4">
        <location>
            <begin position="108"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="4">
        <location>
            <begin position="233"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="domain" description="EH" evidence="3">
        <location>
            <begin position="234"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="478"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="319"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="479"/>
            <end position="489"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OBZ83850.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="497" mass="55417" checksum="96EF4C2BD57563B5" modified="2016-11-30" version="1">MTFFSDSGIPVSFLEEIWQTVDQDAKGILTELQFYKALKLIACAQHGVEASEDILSTRVPLPQFQNTHITPMTSSERQSYIQLFESCQPIDGLVSPQQVREVFQQSGLPAETLGKIWLLADTRHSGSLNKTEFIIAMHYISRLIKDPNLMLPTSLPSQVYAEATGNFSHTIRQRSLYSPRIQPTSPHLSQHQSPVMNKAISSPLSQSSVVLSPNMHQIPSTALSGSASFIDPYEKSRYMTYFEQLDSDNNGFIEADEAVYFFNHSGLPNSDLGMIWEIADKRHLGKLDLHDFCVAMHLIEMRKKGKSIEQYLNQLSVTSNLLEQQLTEIRHQIKAETERVQSIQMQQQVESKAVQDLEDQIAKVKQELEEAKTKVEELEVNKLRSHTATVLSSPTVSSSTPALSFTMSPRSETGSSIFDSFAGFNKANTTLSPYMGQSKKPVKSNDPFDLSAFDALSVKPIQSGSSIKDDLASLFAPVPSNTSKPTNTHSDFDSIFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-06-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N497</accession>
    <name>A0A1C7N497_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_08009</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000580">
        <property type="protein sequence ID" value="OBZ83942.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N497"/>
    <dbReference type="InParanoid" id="A0A1C7N497"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008889467" evidence="1">
        <location>
            <begin position="20"/>
            <end position="126"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ83942.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="126" mass="12961" checksum="66629C2369A50FF3" modified="2016-11-30" version="1">MHKSLYSACFLYLALTVMGQQDAQSPLDIISSISAAIPTEIAGPLSAIVNSPFVISQASAQVTNLPPILQGVAYSILAQATETAPAQATETAGSGSSKPTEILKPSTSIVSSGSQFIHPMSMIIAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N4F1</accession>
    <name>A0A1C7N4F1_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_08042</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000585">
        <property type="protein sequence ID" value="OBZ83907.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N4F1"/>
    <dbReference type="InParanoid" id="A0A1C7N4F1"/>
    <dbReference type="OrthoDB" id="418169at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43991:SF9">
        <property type="entry name" value="DUF2415 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43991">
        <property type="entry name" value="WD REPEAT PROTEIN (AFU_ORTHOLOGUE AFUA_8G05640)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="10"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="32"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="47"/>
            <end position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ83907.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="672" mass="77143" checksum="B4F5051CA47B800F" modified="2016-11-30" version="1">MNYYEHDGLNQEEDDSDYSLDYEYLGPRKPNYRNNQDSDSIASELSDASDEDGFDMWDEDPYSTNDFTWESNDMRLTGFIKRRQKELTKWRNTAPWSQSSFWRKEKGWPQQLPASNSTTNHDQSANALTLVLSDYGTHERLLAVYRDRIIECGQPLNETVTSIKNTITWLDSQQSQPTSDLTQSCHKFVETHASISIPKPVRSLKTIESPTTSNSSISSVNNSHVASKLVPYTKYVQRSQYPAPQNVYLALEFEPLCLAKKYGYMAIGGIEGEFELYCSMHEKPVKIWGTKFKGKNNVLLMTNAVQIVRWNKKEDQHTYYLIACMNDAGVLIYELPNHQHCQQHHSPAIQLQCHIRAFDHVPINDARISPDGSHIICIGDDACVFHIAVSLDQHHRLVFGTPTRLNISKEVLSHSYKPSPINDLPPSTYSSQYVAWSASSLYFAHTSDTHSHVFIWRTQPQIEMVYRIDAAGYTYAIQFHPELEGVLVFSNRYGYLHTVNLEECMTQEGLPVKLMDYNLEFSKRNEGNWLRYTEQSEHCCTPVCLKGTDTVCHTNHLVVRHEITMISFRGEKNKQLRILAKINGLQWSRDGSFLYVSTKKRVLAYKFVSGHIQSLKKIAAQAALAILEKGSVTGKRKRDQLSVQQTWSKKWNDLPPHLQSNILDNTHFASHW</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N522</accession>
    <name>A0A1C7N522_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">RNA polymerase II-associated protein 3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">Rpap3</name>
        <name evidence="8" type="ORF">A0J61_09516</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the RPAP3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000868">
        <property type="protein sequence ID" value="OBZ82434.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N522"/>
    <dbReference type="STRING" id="101091.A0A1C7N522"/>
    <dbReference type="InParanoid" id="A0A1C7N522"/>
    <dbReference type="OrthoDB" id="629492at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0101031">
        <property type="term" value="C:protein folding chaperone complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051966">
        <property type="entry name" value="RPAP3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025986">
        <property type="entry name" value="RPAP3-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013105">
        <property type="entry name" value="TPR_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46423">
        <property type="entry name" value="RNA POLYMERASE II-ASSOCIATED PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46423:SF1">
        <property type="entry name" value="RNA POLYMERASE II-ASSOCIATED PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13877">
        <property type="entry name" value="RPAP3_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13414">
        <property type="entry name" value="TPR_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07719">
        <property type="entry name" value="TPR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 5" id="KW-0802">TPR repeat</keyword>
    <feature type="repeat" description="TPR" evidence="5">
        <location>
            <begin position="72"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="5">
        <location>
            <begin position="140"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="domain" description="RNA-polymerase II-associated protein 3-like C-terminal" evidence="7">
        <location>
            <begin position="286"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="23"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="217"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="220"/>
            <end position="253"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00038275"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00040133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF13877"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OBZ82434.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="407" mass="46173" checksum="2C8DC8107CF93CAF" modified="2016-11-30" version="1">MSKVDQLWKDLAQWQKEIDAKDQAISRRKPVHDQTLPPVRPSTTIQLDNLKPVGLNSLDVKQPTSSTQTERAEAEKAKGNDYFVKKDYANAIQHYGQAIQLNPTVPVYFVNRAMAYLKLNRFLEAEKDCTQGLLLQPKNVKALWRRGIALKGLGRVNEARKDLEHALTIEPNNKSILDELNKLPPPVAEKRRLPVKVIDAAYSGPKGPAKVTAIVTPTDKSTKAEPAKAKPTKVEPVKAEQAKKVEPTKKVEPVKAQPVKAQPVKAETSPQKPLPKATLPLKFTTPRTNFEFERDWKTYKARGDDILYQYFQCIPPSSFANLFKSSLESDQFEKMIDLLETRYLKEKSSQETLEVIQGLSQVKRLDMLIMFLDRKRQQALQGVFDVLKQHVDQEKLSKLAKIYGTRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N5A3</accession>
    <name>A0A1C7N5A3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">G-patch domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_07781</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000546">
        <property type="protein sequence ID" value="OBZ84168.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N5A3"/>
    <dbReference type="STRING" id="101091.A0A1C7N5A3"/>
    <dbReference type="InParanoid" id="A0A1C7N5A3"/>
    <dbReference type="OrthoDB" id="21470at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000467">
        <property type="entry name" value="G_patch_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051189">
        <property type="entry name" value="Splicing_assoc_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14195">
        <property type="entry name" value="G PATCH DOMAIN CONTAINING PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01585">
        <property type="entry name" value="G-patch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00443">
        <property type="entry name" value="G_patch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50174">
        <property type="entry name" value="G_PATCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="G-patch" evidence="2">
        <location>
            <begin position="344"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="51"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="122"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="318"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="60"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="322"/>
            <end position="334"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50174"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ84168.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="385" mass="44301" checksum="2416B665446849AC" modified="2016-11-30" version="1">MAKNKPKSKASNFKRKKIEKKNRARDNAFGFSQSKAIKEYEGYVSYDSDDLLEPTVTQYQEEEEEEEEEEEEEVFIVSQDQPRAKTFNQLSQLSVFDLVQPNPTPDIEGDLGFFIDTTPTLPPKKKHRKEIAESPDRPAKKKHERKILKDESIFIEDDDDDDISISSSEDIDVLHALSHWGSQTDLQFDQPVRVHRRSDHDDFALLEATFYQDIFTEEKTTVDTPKQLPSVLDTILNDFIQQDHMQTYSLSHLSHHGRTMIVPILAKLFQLTTTENKRHIKLEKTSSTCIPSSFIDYKHQLQKKTKIKLSPYEKKIKKRQDKKSFKENELHGKEVASNSVPIPASNKGHRMLSAMGWKEGDAIGKDGIKEPVKAFMRANRRGLGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N5H5</accession>
    <name>A0A1C7N5H5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">rRNA methyltransferase 2, mitochondrial</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">rlmE</name>
        <name evidence="9" type="ORF">A0J61_07568</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000517">
        <property type="protein sequence ID" value="OBZ84383.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N5H5"/>
    <dbReference type="FunCoup" id="A0A1C7N5H5">
        <property type="interactions" value="288"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N5H5"/>
    <dbReference type="InParanoid" id="A0A1C7N5H5"/>
    <dbReference type="OrthoDB" id="20105at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008650">
        <property type="term" value="F:rRNA (uridine-2'-O-)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.150:FF:000005">
        <property type="entry name" value="Ribosomal RNA large subunit methyltransferase E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01547">
        <property type="entry name" value="RNA_methyltr_E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050082">
        <property type="entry name" value="RNA_methyltr_RlmE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002877">
        <property type="entry name" value="RNA_MeTrfase_FtsJ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015507">
        <property type="entry name" value="rRNA-MeTfrase_E"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10920">
        <property type="entry name" value="RIBOSOMAL RNA METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10920:SF18">
        <property type="entry name" value="RRNA METHYLTRANSFERASE 2, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01728">
        <property type="entry name" value="FtsJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005461">
        <property type="entry name" value="23S_rRNA_mtase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 9" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="5 7" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="4 9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Ribosomal RNA methyltransferase FtsJ" evidence="8">
        <location>
            <begin position="35"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="7">
        <location>
            <position position="168"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009258"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00041184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR005461-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OBZ84383.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="222" mass="24924" checksum="5467AFFD13471EC9" modified="2016-11-30" version="1">MIVLPSCRFYSTSSKQWMARQARDPYCKLAKANQYRARSAFKLVQINDKYKLIKRNHVVVDCGAAPGGWTQVAAERVSRQGLVIGIDLLPIDPIPNAHLIQGNFMQQRTQQAIRQILQDRPVHLVCSDMAPSFSGHHVADHARSMELCESALAFAEKVLAPGGSFVAKFLMGGTEHEFRKRLQTLFEKVKTEKPDASRKQSTEGFFVAMGYKSDKDNKDILS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N5I2</accession>
    <name>A0A1C7N5I2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 8">Mediator of RNA polymerase II transcription subunit 4</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7 8">Mediator complex subunit 4</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8 10" type="primary">MED4</name>
        <name evidence="10" type="ORF">A0J61_09345</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Component of the Mediator complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 8">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the Mediator complex subunit 4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000829">
        <property type="protein sequence ID" value="OBZ82604.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N5I2"/>
    <dbReference type="FunCoup" id="A0A1C7N5I2">
        <property type="interactions" value="32"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N5I2"/>
    <dbReference type="InParanoid" id="A0A1C7N5I2"/>
    <dbReference type="OrthoDB" id="1929813at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070847">
        <property type="term" value="C:core mediator complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016592">
        <property type="term" value="C:mediator complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003712">
        <property type="term" value="F:transcription coregulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019258">
        <property type="entry name" value="Mediator_Med4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13208">
        <property type="entry name" value="MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13208:SF2">
        <property type="entry name" value="MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10018">
        <property type="entry name" value="Med4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0010">Activator</keyword>
    <keyword evidence="6 8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0804">Transcription</keyword>
    <keyword evidence="4 8" id="KW-0805">Transcription regulation</keyword>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="177"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="179"/>
            <end position="190"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009626"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00020629"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00031257"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU364141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OBZ82604.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="226" mass="25972" checksum="4FC5EBBCB41187AA" modified="2016-11-30" version="1">MESSLRQQVHEHITEYSDLVKKYFASLSAVAENASIEKANRPEEIIKQMAFVDQKLQQAVEHIENHQARQQQIASVQDEIQQHNIALLEIIQKLGTVRDELDLSLAEAKIELKAIKYASDSNVQFTDVLSYASKLSKYTSAPPNFDSGNRDIRVDFEKPYPDEERMRRGLLYWQNTPQHHKEDQFEHSDSESSADEEMVDVTNARPNEDSGGDPFWILDLNPDMQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N5K5</accession>
    <name>A0A1C7N5K5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Amidohydrolase-related domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">A0J61_07565</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000517">
        <property type="protein sequence ID" value="OBZ84380.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N5K5"/>
    <dbReference type="STRING" id="101091.A0A1C7N5K5"/>
    <dbReference type="InParanoid" id="A0A1C7N5K5"/>
    <dbReference type="OrthoDB" id="10258955at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016810">
        <property type="term" value="F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.140">
        <property type="entry name" value="Metal-dependent hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006680">
        <property type="entry name" value="Amidohydro-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013108">
        <property type="entry name" value="Amidohydro_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011059">
        <property type="entry name" value="Metal-dep_hydrolase_composite"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051781">
        <property type="entry name" value="Metallo-dep_Hydrolase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43135">
        <property type="entry name" value="ALPHA-D-RIBOSE 1-METHYLPHOSPHONATE 5-TRIPHOSPHATE DIPHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43135:SF3">
        <property type="entry name" value="ALPHA-D-RIBOSE 1-METHYLPHOSPHONATE 5-TRIPHOSPHATE DIPHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01979">
        <property type="entry name" value="Amidohydro_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07969">
        <property type="entry name" value="Amidohydro_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51338">
        <property type="entry name" value="Composite domain of metallo-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="Metallo-dependent hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="32"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="domain" description="Amidohydrolase-related" evidence="3">
        <location>
            <begin position="433"/>
            <end position="524"/>
        </location>
    </feature>
    <feature type="domain" description="Amidohydrolase 3" evidence="4">
        <location>
            <begin position="814"/>
            <end position="993"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="8"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF07969"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OBZ84380.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1012" mass="111589" checksum="274257FE7B908F2E" modified="2016-11-30" version="1">MNQRRNKSSTEPLLNTPSYHGRQKSNQKTTRLVLIASALALFGSSCIYLSHKLPTILLPTDTLKTQGLWQQDPPAVTPGISARSFEHGLAQCQFNLDRAQAKTNTTRVRHRNPRRAPEAHDTLIEHAHIWLGDRYLEDGQIYLRQGLIAAVGHDLDVPKGIRRLDAEGRVVTPGLIDMHSHMTVDSLNGLSASDDTNEMTHPTTPYVRVIDALSPTDPAIKLVASGGITTSLILPGSGNLIGGEAAVIKLRPVPTLSNQDMLVSAGSEEEDQEIHWRFMKMACGENPKAFYGPVRKQMPSTRLGEAYLFRRSFEKAQTLMRQQDDWCDAAYRLSKTDKTMRLAEPYPEDLKLESLVALLRKQVNLNVHCYLPQDFEAMIRHSIEFDFEIAAFHHALSAWQVPEIIKRAKNNITIATFADMWGYKAEAMDQNVHAPKILDAAGIPVAFKSDHPVISARDLLFEAQKAYHYGFDEHKALQALTTVPATSLKLNHRIGSIAVGKDADLVIWERHPLRLGARPTHVFVDGAELDFQASWTKSVSEQPQEKMTTQKTSKSHHVLPSLSNSTMRLEDHGLDNPHLFSDACHSGVSSFVLRNISQIYMNASSTLHAPDGQGLYLVVDQGQIRCLGVSCDRDSVDWPVSSPVFNMGGAVILPGIVSMGVPLGLFEVQSEDATYDGVVKKDASTSEEVVRAVDGLKLNGLRLQKAYKAGKYLEDLKYRHKSTQYLCSGVTTAIAQPVTYESLIPGLSVGFRTGTENSILDAQALIKEEAALNFVIQHGSVTYILLTSTGLTVSQQIAKIRDLLISNIHKDTKTNVFARAAQGQLPIVVQVDDKDEIASLLRLKQTIQQDHQRDLQLVILGGSESYLLADHLNRLQVPVILMPARCFPSTWQSRLCLAGPPVTPWNALDILIQHGVQVGLGSTDPDNGDARNLIWEAGWNLAHNTQLTPSQAVGLVTWNMADILGLPEIGQLREGGPAEFVAYNNNPFQFGTQVLMVHGGGRSGPTCFPQQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-06-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N618</accession>
    <name>A0A1C7N618_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_07857</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000557">
        <property type="protein sequence ID" value="OBZ84086.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N618"/>
    <dbReference type="InParanoid" id="A0A1C7N618"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ84086.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="69" mass="7691" checksum="DF96330A7927E5A7" modified="2016-11-30" version="1">MLRCKRVFGTSARHPNTASARFVVNGSNISHSTNISNINIQKKKKLLAMQLDEPAARLSGQGNLWRNEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N6W1</accession>
    <name>A0A1C7N6W1_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">START domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_07148</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000467">
        <property type="protein sequence ID" value="OBZ84801.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N6W1"/>
    <dbReference type="InParanoid" id="A0A1C7N6W1"/>
    <dbReference type="OrthoDB" id="196858at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.530.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023393">
        <property type="entry name" value="START-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051213">
        <property type="entry name" value="START_lipid_transfer"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19308">
        <property type="entry name" value="PHOSPHATIDYLCHOLINE TRANSFER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19308:SF14">
        <property type="entry name" value="START DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55961">
        <property type="entry name" value="Bet v1-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="1461"/>
            <end position="1483"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="299"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1100"/>
            <end position="1128"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1313"/>
            <end position="1361"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1407"/>
            <end position="1437"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="305"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1315"/>
            <end position="1330"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1409"/>
            <end position="1422"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ84801.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1527" mass="172018" checksum="26ABFEE655CE89BD" modified="2016-11-30" version="1">MSAKKANQENINWVERVTQKRCQVRYVSTIADHSQSYYFGLQVDLNQHTVVSYLRWDSVVLNASDVSHMLLSFFNHLTNPPISAWISQCDESIVIQHQSYQEESYTIDYIYQLNQTKLSTNALEIHRKINQHHRWHSGSWDQQTLRRTNFLSSSLLLNSASSSPQIHPVARSSYPDNRQMFPWATNDDDDDEVYLSQLDSDELCIQMIDKPDVSLLVIDKPTWSEKFSQQCVQLYDQGSKGYMLQIIHPRLWMQQLKENLEEIMKLDDEDSTSIHIQLTLQKSKNSVCTVNGIEWPIKSRTLSSSDEEDNDTGQSDQEDIFVDGMEEIASPKLTEIPKMRHLLIKPSSSAPVPTLQTTNDNDDLDVCQKKPASIHEPVDSTLSHTTIDSFVPDIHLSKQDTISPREHAGTSTYLNSTQGIDQLAESEPIALQKIYPQFIDYLQPSSASIIQAPSKENGYVTIKSFPIPNHPMGGFLSESRWKNCSLWDIKAVIETAGARRVWDTTFENAVFLHSLTTTSALWHTKLKGAWPVQPRDYVCFHGQYAFPNHIDLLSTSCFGDTFQYKPLPQKNVPGYTRATMDLAGCRIERIDQTSVLVRQVVVTQFPSWVIQYLTSRALVQTCSAIQFARDYLETHGAPPSLMGLECASLGDVKYDHERKSWRCEYTRSASKDESTSTITSVIIRLDKKKWTTNHYSVVIDPPPSNTSAVEKSHDPTGVWLSVEHDEAYIIPFRGKILVLIKLETSAVAETKENGLQVNGVMTPIQKKEEECVHLYQEPLKKSHQELDPSMKLNEAVDRGLDDAAIKQHAQTALSFLKQAEEEFGWNIISDNHRSGIRISKRSSIKDNRSSKGLTDTHQTPLFQVVEPYMVYKGSKVMENFSVDEILAVIKDTGHVRASHDDTIESPTEVVHQTDAPACKIIRHAVKAVFPFKSRDVYAVSCLATECTSVQRALYVESALPDSPAIQSKKPMVSFYLSGWILEEVDPYSTKTNHPIPSTRVTHVGSLDLGSSIPSYISNLVANNWFPRKLNAVEAFLKLKGPPPFLTQPNFALDFTNNVIMAQASNVEWSQVYWCYNEQHHVEFKAHLRLVEHEGILRKRQGKEVDSKPSKHATSISDISHRRGSLPSTILPKSRLNLTTSASTSTVTKNIPVSSVEKTVTITTRGHILLQMTMDLRAFENGYEIETQLFDLTDKMNRSNATHKLRLSISEPSLAQLMDGKKQVSKHTIVIQTKQGKPLSSSLPALFEFYFKLIPIEKEKLSERAKKLTVSHVLKADIGADKNEWDGLILVNGQEIQPQNEVELRALKDEEAPLAETQSISVSDPTSPSKHTTSDRESDVSVLDVKQLDLPSGTVNKSQSESDKISQFAKSGGVVATALGNVSASVNTIGAHMMSPFKTASGSFLSSSSTDLNNKAQPDSEQTLGEKEHPFKKQVSTENDHAKTHSYCRQLSSMVNGCVPKWILLFIASLIILVMLTLLLLYFASLKLEWIFFNNLDYTTEQQMLCQLLHTTWFGEWDIQIVATRRAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N712</accession>
    <name>A0A1C7N712_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Peptide hydrolase</fullName>
            <ecNumber evidence="10">3.4.-.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">qpct</name>
        <name evidence="12" type="ORF">A0J61_07094</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>N-terminal L-glutaminyl-[peptide] = N-terminal 5-oxo-L-prolyl-[peptide] + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:23652"/>
            <dbReference type="Rhea" id="RHEA-COMP:11736"/>
            <dbReference type="Rhea" id="RHEA-COMP:11846"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:64722"/>
            <dbReference type="ChEBI" id="CHEBI:87215"/>
            <dbReference type="EC" id="2.3.2.5"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the glutaminyl-peptide cyclotransferase family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the peptidase M28 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.-.-" evidence="10"/>
    <dbReference type="EMBL" id="LUGH01000462">
        <property type="protein sequence ID" value="OBZ84851.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N712"/>
    <dbReference type="STRING" id="101091.A0A1C7N712"/>
    <dbReference type="InParanoid" id="A0A1C7N712"/>
    <dbReference type="OrthoDB" id="3907302at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016603">
        <property type="term" value="F:glutaminyl-peptide cyclotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd03880">
        <property type="entry name" value="M28_QC_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.630.10:FF:000029">
        <property type="entry name" value="Glutaminyl-peptide cyclotransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.10">
        <property type="entry name" value="Zn peptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037457">
        <property type="entry name" value="M28_QC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007484">
        <property type="entry name" value="Peptidase_M28"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040234">
        <property type="entry name" value="QC/QCL"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12283">
        <property type="entry name" value="GLUTAMINYL-PEPTIDE CYCLOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12283:SF6">
        <property type="entry name" value="GLUTAMINYL-PEPTIDE CYCLOTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04389">
        <property type="entry name" value="Peptidase_M28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53187">
        <property type="entry name" value="Zn-dependent exopeptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="8" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-0645">Protease</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0964">Secreted</keyword>
    <keyword evidence="10" id="KW-0732">Signal</keyword>
    <keyword evidence="5 12" id="KW-0808">Transferase</keyword>
    <keyword evidence="7 10" id="KW-0862">Zinc</keyword>
    <feature type="signal peptide" evidence="10">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008810986" description="Peptide hydrolase" evidence="10">
        <location>
            <begin position="20"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M28" evidence="11">
        <location>
            <begin position="97"/>
            <end position="333"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU361240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF04389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="OBZ84851.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="350" mass="40054" checksum="47B5F7867E7CBD08" modified="2016-11-30" version="1">MVLLTWTLLLSILPCFVLAYKELNNEALRQLGKLTQTQRLSVTGDLMKPLLVERIADTPGNKQVREFIVRHFTSLGWHVELDEFVDTTPFGNKSFANIIVTHNPDKPTRLVLAAHYDSMYSPDFEFIGATDSAVPCGILMNIAETINYMLSDTSIHYRQKDKTLQMIFFDGEEAFHQWGPTDSIYGARHLASHWEGSVVASPTKTLKNKLDQIEVMVLLDLLGVANTQFPNYYRSTSWLYDKLYDLEYRLNNQSILKTVSSKTGENLKSLFNPNSFLTFRGDMIGDDHVPFLMRGVNILHMIPYPFPNVWHNRLDNADCIDANVVENLSTLFRVFTAEYLELDPLPHNEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N7A7</accession>
    <name>A0A1C7N7A7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">N-acyl-phosphatidylethanolamine-hydrolyzing phospholipase D</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">NAPEPLD_1</name>
        <name evidence="2" type="ORF">A0J61_08735</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000701">
        <property type="protein sequence ID" value="OBZ83214.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N7A7"/>
    <dbReference type="STRING" id="101091.A0A1C7N7A7"/>
    <dbReference type="InParanoid" id="A0A1C7N7A7"/>
    <dbReference type="OrthoDB" id="332863at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070290">
        <property type="term" value="F:N-acylphosphatidylethanolamine-specific phospholipase D activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070291">
        <property type="term" value="P:N-acylethanolamine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070292">
        <property type="term" value="P:N-acylphosphatidylethanolamine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="entry name" value="Ribonuclease Z/Hydroxyacylglutathione hydrolase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024884">
        <property type="entry name" value="NAPE-PLD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15032">
        <property type="entry name" value="N-ACYL-PHOSPHATIDYLETHANOLAMINE-HYDROLYZING PHOSPHOLIPASE D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15032:SF4">
        <property type="entry name" value="N-ACYL-PHOSPHATIDYLETHANOLAMINE-HYDROLYZING PHOSPHOLIPASE D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12706">
        <property type="entry name" value="Lactamase_B_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF038896">
        <property type="entry name" value="NAPE-PLD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="Metallo-hydrolase/oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Metallo-beta-lactamase" evidence="1">
        <location>
            <begin position="154"/>
            <end position="345"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12706"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ83214.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="384" mass="44321" checksum="89BF9BFE44604D81" modified="2016-11-30" version="1">MPSSKRPSFVNFPIPFDHPYTIPTLAITMGASALLYYSLQAQHERDLKEAIRQRVISKRKNCKRKEDKFASLKIEKQFVNPFQEWSSPHVSFLDSILYWFGINNNNQVPKIEQDLLASLPLVQPPLDQIRQTQKTTFTWLGQSTCLFGLEGLKILTDPIFDHPNRLRPPPCQIEELKDMIDVVLVSHYHFDHLDEDTAIKLGNDVTWYIPLGLREWFVKRGIDNVIELDWFQELHHKGRPDILIACVPAMHQSGSRHAFEKDESLWCSFVVKSKSDRIFFCGDTGYVPELFQSIRDLYAPFTLAALPIGTYEPRQMLKSLHMNPQEAFQAHQDLGCPQLSVGIHWGTFMKSNEPYLSPSQQLSELTKSKHQQFITTAFGETLFM</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N7B3</accession>
    <name>A0A1C7N7B3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_07432</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000501">
        <property type="protein sequence ID" value="OBZ84516.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N7B3"/>
    <dbReference type="InParanoid" id="A0A1C7N7B3"/>
    <dbReference type="OrthoDB" id="2319746at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ84516.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="162" mass="18625" checksum="B884A55A39A79F97" modified="2016-11-30" version="1">MNFSCGCLFDKKVKEPHFKKSAHFEDLSASFAINAKNEQLGAHYSWLVQLHKPFQSKAYIEATFEDPTHPSDPIVVPAIQLQPEPPETFEHPRYYFLSPALGALDCKLYDIKITAYKDKTRQQVLTEHKNQLLSRINSDSCVKSEFIEKMRAAASYADWQEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N7C9</accession>
    <name>A0A1C7N7C9_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Trehalase</fullName>
            <ecNumber evidence="4">3.2.1.28</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">Alpha-trehalose glucohydrolase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">NTH1</name>
        <name evidence="5" type="ORF">A0J61_07082</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>alpha,alpha-trehalose + H2O = alpha-D-glucose + beta-D-glucose</text>
            <dbReference type="Rhea" id="RHEA:32675"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15903"/>
            <dbReference type="ChEBI" id="CHEBI:16551"/>
            <dbReference type="ChEBI" id="CHEBI:17925"/>
            <dbReference type="EC" id="3.2.1.28"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the glycosyl hydrolase 37 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.28" evidence="4"/>
    <dbReference type="EMBL" id="LUGH01000460">
        <property type="protein sequence ID" value="OBZ84868.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N7C9"/>
    <dbReference type="STRING" id="101091.A0A1C7N7C9"/>
    <dbReference type="InParanoid" id="A0A1C7N7C9"/>
    <dbReference type="OrthoDB" id="3542292at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004555">
        <property type="term" value="F:alpha,alpha-trehalase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005993">
        <property type="term" value="P:trehalose catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008928">
        <property type="entry name" value="6-hairpin_glycosidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012341">
        <property type="entry name" value="6hp_glycosidase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001661">
        <property type="entry name" value="Glyco_hydro_37"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018232">
        <property type="entry name" value="Glyco_hydro_37_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23403:SF6">
        <property type="entry name" value="CYTOSOLIC NEUTRAL TREHALASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23403">
        <property type="entry name" value="TREHALASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01204">
        <property type="entry name" value="Trehalase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00744">
        <property type="entry name" value="GLHYDRLASE37"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48208">
        <property type="entry name" value="Six-hairpin glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00928">
        <property type="entry name" value="TREHALASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="2 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005615"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU361180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OBZ84868.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="364" mass="42185" checksum="FD11B5AE87E46503" modified="2016-11-30" version="1">MEAYNKGDIQEPKLDEYFLHDRAVRESGHDTTYRYEKVCANLATVDLNTLLYKYETDIADAIDRYFDGELAYDKKGEDGEIVTIRQHAMTWRKRAEERLKRINTYLWNEEKGMYFDYDTVLKKQANYESVTTYWSLWAGCASQEQAEKMIERSLCKFEVLGGLVSGTEESRGITSLDRPNRQWDFPFGWAPHQIMAWQGFQNYGKRDIAERLAYRWLYTITKSFVDFNGVVPEKFDIVGMTHKVQVEYGNVGVDFKYVPREGFGWMNASYQIGLHLISTKMRRALGACTHPDLFFEKTNHGNYDLSRHRKRRQSAEAAARKITHNGQITAAITRIGSNASSIHPTTVVSDQMTHHAFLELTESQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N8A6</accession>
    <name>A0A1C7N8A6_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF6729 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_06580</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000404">
        <property type="protein sequence ID" value="OBZ85365.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="InParanoid" id="A0A1C7N8A6"/>
    <dbReference type="OrthoDB" id="2287981at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046616">
        <property type="entry name" value="DUF6729"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24401">
        <property type="entry name" value="SI:CH211-243P7.3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24401:SF29">
        <property type="entry name" value="SI:CH211-243P7.3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20499">
        <property type="entry name" value="DUF6729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF6729" evidence="2">
        <location>
            <begin position="112"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="42"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="234"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF20499"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ85365.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="234" mass="27026" checksum="CCC3065E45273A24" modified="2016-11-30" version="1" fragment="single">MPNQSTILAAFNSARINSTVQPASTEEPCIDSVPEIIEIADSSNNRDDQDDLQNEIPSEQESQPDLEEDFTVDQEEEFISDSLPEDSFLISYFQKIQSRLCQEDYPSEYSRXTFWIEQMMPYFMLKKNKKIESFYQPRIFLWIPHLLTEERLGGLKCSVCQSKMETKGFNKNPHARRIVDLTSCFYLMSMRYRCLSPRCGKTMNGHDGSIVKQLPLELQMEFPAVLTHKGGVSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-06-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N8C9</accession>
    <name>A0A1C7N8C9_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_06561</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000402">
        <property type="protein sequence ID" value="OBZ85382.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N8C9"/>
    <dbReference type="InParanoid" id="A0A1C7N8C9"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ85382.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="107" mass="12068" checksum="6A131332E793B0CD" modified="2016-11-30" version="1" fragment="single">MEQEIDKRGPDGFPVALGRVLGWLFLWKAIKYVRYRISNTRENMQAYTVQVYLQEATQGANGQEGYGRSAGGESQAVSRIALIIKYRAKEVVAVLTEITRTDSIQEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N8F0</accession>
    <name>A0A1C7N8F0_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">chitin synthase</fullName>
            <ecNumber evidence="2">2.4.1.16</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="19" type="primary">CHS8_0</name>
        <name evidence="19" type="ORF">A0J61_07033</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="19 20" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19 20">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="15">Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="19">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.16" evidence="2"/>
    <dbReference type="EMBL" id="LUGH01000455">
        <property type="protein sequence ID" value="OBZ84916.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N8F0"/>
    <dbReference type="InParanoid" id="A0A1C7N8F0"/>
    <dbReference type="OrthoDB" id="370884at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030428">
        <property type="term" value="C:cell septum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016459">
        <property type="term" value="C:myosin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003779">
        <property type="term" value="F:actin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004100">
        <property type="term" value="F:chitin synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003774">
        <property type="term" value="F:cytoskeletal motor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006031">
        <property type="term" value="P:chitin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031505">
        <property type="term" value="P:fungal-type cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd04190">
        <property type="entry name" value="Chitin_synth_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd14879">
        <property type="entry name" value="MYSc_Myo17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.530">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.120.10">
        <property type="entry name" value="Cytochrome b5-like heme/steroid binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.850.10">
        <property type="entry name" value="Kinesin motor domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.720">
        <property type="entry name" value="Myosin VI head, motor domain, U50 subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="entry name" value="Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004835">
        <property type="entry name" value="Chitin_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001199">
        <property type="entry name" value="Cyt_B5-like_heme/steroid-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036400">
        <property type="entry name" value="Cyt_B5-like_heme/steroid_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036961">
        <property type="entry name" value="Kinesin_motor_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001609">
        <property type="entry name" value="Myosin_head_motor_dom-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036037">
        <property type="entry name" value="MYSc_Myo17"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22914">
        <property type="entry name" value="CHITIN SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22914:SF13">
        <property type="entry name" value="CHITIN SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03142">
        <property type="entry name" value="Chitin_synth_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00063">
        <property type="entry name" value="Myosin_head"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00193">
        <property type="entry name" value="MYOSINHEAVY"/>
    </dbReference>
    <dbReference type="SMART" id="SM01117">
        <property type="entry name" value="Cyt-b5"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00242">
        <property type="entry name" value="MYSc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55856">
        <property type="entry name" value="Cytochrome b5-like heme/steroid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51456">
        <property type="entry name" value="MYOSIN_MOTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="14 15" id="KW-0009">Actin-binding</keyword>
    <keyword evidence="8 15" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="13" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="4" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="11 17" id="KW-0472">Membrane</keyword>
    <keyword evidence="12 15" id="KW-0505">Motor protein</keyword>
    <keyword evidence="10 15" id="KW-0518">Myosin</keyword>
    <keyword evidence="7 15" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="6 17" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 17" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="887"/>
            <end position="904"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="925"/>
            <end position="944"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="1194"/>
            <end position="1213"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="1589"/>
            <end position="1610"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="1616"/>
            <end position="1637"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="1644"/>
            <end position="1667"/>
        </location>
    </feature>
    <feature type="domain" description="Myosin motor" evidence="18">
        <location>
            <begin position="10"/>
            <end position="758"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="577"/>
            <end position="624"/>
        </location>
    </feature>
    <feature type="region of interest" description="Actin-binding" evidence="15">
        <location>
            <begin position="636"/>
            <end position="658"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="1726"/>
            <end position="1747"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="16">
        <location>
            <begin position="598"/>
            <end position="607"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="16">
        <location>
            <begin position="613"/>
            <end position="622"/>
        </location>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <begin position="111"/>
            <end position="118"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012543"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS51456"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="OBZ84916.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="1812" mass="205785" checksum="A1774F0C2D2DA7E1" modified="2016-11-30" version="1">MQDDSRIDLTCLLNPSSLQPPSEDSIVNLLATRYKRNQPYTRLGHSALIVLNPYQPLDILNDATLQSYADNGYRSLAENKPFMQPHIYDLAARVYFHMRRTGEDQSVILSGITGSGKSTTRSHLLNQILLLSTHSKKESKLQQQIKSSLVILEAFGNAKTVQNLSASKYGIFQELQFSERGRILGAKTLTYAFDKSRVTSAPKEERSLNVFYSLLAGTSAEEQTALHINFPPESFHYLAQSRTIKTADVNDAIAFADLKSSLKTCGFKAKTVTQIFQLLATILHIGNLQFQDDYDGVNNIGGGNQAQEACSVRNRDVLDSVAIMLGVSPTKLEQSLTYKLRLIRKELCTMFLNTQGALEQRDALARALYHVLFLWIVESINTKICYNDSEPANFIGVLDQFGFQNFKTNGFEEFCVNFANERVQQFLIEHQLDPSTGLNAIMVSDGLPFPQLNWTDHFACLDLLIGKEENQPLGGLIGLLDRDCVKYQSGATDATNANFLANVQRAYGTHPSFAKSGHAYAFGINHFSGAVHYTVESFLEKNLDDLSPDFVSLLRDNSTNAFVSCLFEGTAMATESHPKDDRTIVKAQLTSKPTRAPSMKRNHKRRNQPQEQEEPKRPKEEDMQVTTVVDQLYMTLRDLFSTIAETRIYNVIHIRPNDTQSPDALDIKKVKGQLRAFLVPELVVRASVGYANYYTLEEFVLQYEHLVRSLNVDTSRPVYEQAHQVRTMMHWSDDQVFVGKEMVWMAYGTWKELEDGLRLSEKAERERLKNADSKQTPMESQAQMTANAMGYPEYYTDAHLMHGAQEDYPQHLSPMHVFEDTASYLESEDGIKRDMDGSQWGEESEWGMKGLSEGFGPNMDMSKMVEDYHTPQHESVEEVPITAVRIWWVRFVWLMTWWIPSPFLRWFGKMKREDIQMAWREKVTLCIIIFFFSAITIFVIVGLGEAICPGTREMYSPANVGAHSTPSDMFVSVRGLVYDITNFARNAHGTTAVGATKEALEQLAGQDVSYLVPPPLTVACQQLVSSSTVKIIPNATTTLAGFVHGSGDQAAPASSNKLQSPEWYWSYFLPTMSIYKKGKLVITINQLADDYKGWTRRALAIHGKVYDIHDYFATAALYDAGTAPNQRSSYRFLSKQVEEFFMTFSGSDATDKWDQYKNSMSAEEQAVNLNCLNNYFYIGDVDERESIRCMFTNYMLLAAAILMCSVIVIKFLAALQFGGAPLPEDHDKFVICQVPCYTEDEESLKKTIDSLTVMNYDDKRKLLYIIADGMIMGSGNDRPTPRIVLDVLGYDTKNDPEPLMFKSIGEGSKQLNYGKVYSGLYECEGHVVPYIVVVKVGKASERAKPGNRGKRDSQMICMNFLNKVHFDSEMTPLELEMYHQIKNVIGVDPSLYEYILMVDSDTEVLPDALNHMISRMLHDGRIIGICGETKLVNEDRSWTTMIQVYEYYISHHLAKAFESLFGSVTCLPGCFCMYRIRTPVKNEPLIISPKVIHDYSDNHVDTLHKKNLLHLGEDRYLTTLMMKHFPQYKMKFTPHAQCKTVAPDRWQILLSQRRRWINSTIHNLFEVVLLPDLCGFCCFSMRFVVLIDLIGTLTLPVSVVYMVYLIYVIASHTGPIPVLALAMLAGIYGLQAILFILKRQWQQIGWMIFYILAIPVFSFFLPIYSFWHFDDFSWGNTRVVVGDKKQKKIIVADDEKFDEKMIPLKKWSAYEQELWEMGSTGSKETGLTGHSYRSHHSRGSRGNQSGVFDNRSHYGASQIGEFDYYRNAQSAVFDNRSHYAGSQLGEYDYYRDNSFSPQPAPGWNHQRNFSPY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N941</accession>
    <name>A0A1C7N941_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Protein unc-50</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">A0J61_06340</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the unc-50 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000379">
        <property type="protein sequence ID" value="OBZ85611.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N941"/>
    <dbReference type="FunCoup" id="A0A1C7N941">
        <property type="interactions" value="419"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N941"/>
    <dbReference type="InParanoid" id="A0A1C7N941"/>
    <dbReference type="OrthoDB" id="10027013at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007881">
        <property type="entry name" value="UNC-50"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12841">
        <property type="entry name" value="PROTEIN UNC-50 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12841:SF6">
        <property type="entry name" value="PROTEIN UNC-50 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05216">
        <property type="entry name" value="UNC-50"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="78"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="108"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="161"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="193"/>
            <end position="212"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006293"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OBZ85611.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="221" mass="25691" checksum="DC43280F568DA0D7" modified="2016-11-30" version="1">MASLLPTSYTSTSPSFHYDAHRSRRQGPLLKRLFRFPHMDFELAFWQLGYLLISPRRVYRNIYYHKQTKNQWARDDPAFLVLLVCFLTLSALAWGWTYQLTIGGILQLMVTMVAVDLFLVGFVIATITWFISNHFLTQPIHHYAVAQKVEWAYALDVHWNASLPVLLILNILQLLFLPLLLKNYWASLLIGNIMYGIALIWYLFGTFLGFSGKCPLYHITT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N950</accession>
    <name>A0A1C7N950_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">PX domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">A0J61_06499</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000394">
        <property type="protein sequence ID" value="OBZ85448.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N950"/>
    <dbReference type="FunCoup" id="A0A1C7N950">
        <property type="interactions" value="20"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N950"/>
    <dbReference type="InParanoid" id="A0A1C7N950"/>
    <dbReference type="OrthoDB" id="2117459at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035091">
        <property type="term" value="F:phosphatidylinositol binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06869">
        <property type="entry name" value="PX_UP2_fungi"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1520.10">
        <property type="entry name" value="Phox-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047168">
        <property type="entry name" value="LEC1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024554">
        <property type="entry name" value="LEC1-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024555">
        <property type="entry name" value="PX-associated"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001683">
        <property type="entry name" value="PX_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036871">
        <property type="entry name" value="PX_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47185">
        <property type="entry name" value="PX DOMAIN-CONTAINING PROTEIN YPR097W"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47185:SF1">
        <property type="entry name" value="PX DOMAIN-CONTAINING PROTEIN YPR097W"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12825">
        <property type="entry name" value="DUF3818"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00787">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12828">
        <property type="entry name" value="PXB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00312">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64268">
        <property type="entry name" value="PX domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50195">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PX" evidence="2">
        <location>
            <begin position="169"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="298"/>
            <end position="317"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ85448.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="803" mass="92207" checksum="D2020CF2656CD06A" modified="2016-11-30" version="1">MDLSPQELHYFKRELISHQLENEIEQIKRSGDLSRLVKASADNKEYPFLEYLCKNFVLEFPLLKNGDDKGFFEKLQTFLDEYSKLRLNNYAPKSARDSQRRVLIYKIHKLMIVALSASIKTTQGEEQSIQLTSEQPTSDEDNLATRLGMTNLESEENYLEWIGLNGLKLNVVTVRDVSEVRTIREHIHSEFIVQTELIIQQDNGTQTTAPVYVAKRHGHFRQLRDDLKAAFPTSELPAVPSKAHDDALPRGNRQLHREKDRIMLRLFLRRLAADSEVANSAIFRDFLLNDPIQLTPEEKADAENRAKMDESRTAEEKRFREEVDKKIVELDGLLNLLKQQVMKPNGLIEVFDVIKNTEKIEQLPVELRKAIEWGRINFAFVLHTQFVTSDRSVENAANLKRTHSLMPYRAIAQVLKLSNPFYMVKGVLDIFLSQPFGQKSLFQRIVLSNMNEQSKELAKDIEELERKINDPLLCQKIANAVQTEIPEGLKLDNSSPINETLELLKDSNIEPVLTPQQILKVAFANQPGREESHKLVQDLYKLWVLHARKQEQESLMSLVFQGVTGEVTKDLFAIFYEPLAQVYKSANISETIGHVSAFVNDLIQVVDNVDAQDASHTAQPFIELVKRHEDKFYDFVHNVHAQDKTKLFDSLLGYVNSIFSFVSTGIPTKIDLDAIVTEAGISESEYPALKQEIQSVCEYHLKRKQRHLERKRQKMMTTSDIADNQEIFDFLPENKQVMNVFNDMAEIGSDSEDDMSIYAESIKSNNGSSSNLKAHEMTLRSPKLHIVPRIGSVFVEHVRRIMY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N9E7</accession>
    <name>A0A1C7N9E7_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">A0J61_06234</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000367">
        <property type="protein sequence ID" value="OBZ85720.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N9E7"/>
    <dbReference type="InParanoid" id="A0A1C7N9E7"/>
    <dbReference type="OrthoDB" id="2446850at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="92"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="116"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="145"/>
            <end position="163"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ85720.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="174" mass="19230" checksum="CE7225DB590D24C7" modified="2016-11-30" version="1">MDNQATISNFVQDGYVRGSWIAFFTLWVLWGITYFIRHAFGRTGYYNNPVTNAAAQDPEAAATGTGTATNKNKLGGVMHSTMADRLARAHEILFENTLLLLSVLVLNTFGVGSTRAVMILAWIFFAFTAVDAFTEVGVNHHFIRLIFNVMFFGVTLAIGGLAFKNGWHHTTSVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-10-08" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N9L2</accession>
    <name>A0A1C7N9L2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Zn(2)-C6 fungal-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">A0J61_06174</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000360">
        <property type="protein sequence ID" value="OBZ85781.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N9L2"/>
    <dbReference type="STRING" id="101091.A0A1C7N9L2"/>
    <dbReference type="InParanoid" id="A0A1C7N9L2"/>
    <dbReference type="OrthoDB" id="39175at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12148">
        <property type="entry name" value="fungal_TF_MHR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00067">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.240.10">
        <property type="entry name" value="Zn(2)-C6 fungal-type DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050815">
        <property type="entry name" value="TF_fung"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036864">
        <property type="entry name" value="Zn2-C6_fun-type_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001138">
        <property type="entry name" value="Zn2Cys6_DnaBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47338:SF5">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47338">
        <property type="entry name" value="ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00172">
        <property type="entry name" value="Zn_clus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00066">
        <property type="entry name" value="GAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57701">
        <property type="entry name" value="Zn2/Cys6 DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00463">
        <property type="entry name" value="ZN2_CY6_FUNGAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50048">
        <property type="entry name" value="ZN2_CY6_FUNGAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Zn(2)-C6 fungal-type" evidence="7">
        <location>
            <begin position="31"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="102"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="103"/>
            <end position="119"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OBZ85781.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="625" mass="71935" checksum="69735E4D5A8009B6" modified="2016-11-30" version="1">MSIQRKKKPVEFHFVDMNDPERYKKLKVARACDFCRRRKSKCDIGIPGSGTCSNCQKHKTVCIFSPVTPNRATEPIRQETPKLQVHALSEFPLLSIESGQAGYERDQADDQQHAYREPPKPAGQEPPLALESQLFQVYFDYVHPVFPVLLEQSVKHIHSQDQLLLPRALRYSIMALACHFLPHPSASFTPGLMTDESHHHYTALYFYKEAIKEIDLVRSNGFHPARLDIVQALLLLYKYQEMVQQSVQGIQHLEDAQQILCRIKATIPQQQEMLTRVRWVVISCICLGNLSNKQLSQLYNRVQLPDELPKALSEETEDSKTPASVTFQRINQFDQLLNLSLLYSHTIQTLMIGSTSELICLYQFKSIRQHWYSTLHPVTQNQLLSLSTFDQQDMDNTTLYSAILYDMLYLLLLQHYRLPETEWDSTEAAYRLQRMIHTWTMQASFKSAIQSQRMASFGLILCLNTHLSKQDQRSIDVSVIDQIRHIMAYTQIDSRVDRELEELSIKMSSKRVTQPSQPIDYFSLAPHHTLHSAASSPFDYPLPSTPGLGDMLSTSTTTIEGLNTPIREEDNPILGQQTTEWIAEQQRQQHLQFQAYQSQQSYAFPTLFMHTPLFSGSEQENPNCI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N9N5</accession>
    <name>A0A1C7N9N5_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">ATP-dependent DNA helicase</fullName>
            <ecNumber evidence="1">5.6.2.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">pif1_13</name>
        <name evidence="3" type="ORF">A0J61_06183</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="5.6.2.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the helicase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.6.2.3" evidence="1"/>
    <dbReference type="EMBL" id="LUGH01000362">
        <property type="protein sequence ID" value="OBZ85760.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7N9N5"/>
    <dbReference type="InParanoid" id="A0A1C7N9N5"/>
    <dbReference type="OrthoDB" id="2288986at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043139">
        <property type="term" value="F:5'-3' DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000723">
        <property type="term" value="P:telomere maintenance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd18809">
        <property type="entry name" value="SF1_C_RecD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010285">
        <property type="entry name" value="DNA_helicase_pif1-like_DEAD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051055">
        <property type="entry name" value="PIF1_helicase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47642">
        <property type="entry name" value="ATP-DEPENDENT DNA HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47642:SF6">
        <property type="entry name" value="ATP-DEPENDENT DNA HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05970">
        <property type="entry name" value="PIF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0227">DNA damage</keyword>
    <keyword evidence="1" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="1" id="KW-0234">DNA repair</keyword>
    <keyword evidence="1 3" id="KW-0347">Helicase</keyword>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA helicase Pif1-like DEAD-box helicase" evidence="2">
        <location>
            <begin position="114"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU363044"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF05970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OBZ85760.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="861" mass="96301" checksum="8D2A49696D2CC8A8" modified="2016-11-30" version="1" fragment="single">IEEAANEFSKLPDDTISRFMEMASNFNFEQDTQRNQDSEEVQAHVEKKEVSNLNDFSMYVLPEDNEIRASQEFTNGERSVRATAPSRPQLNVHARPDIMPEDEHYDMGLERDLSNKSVLLCAPTGKAAFNINGSTVHSTFHLPLNQSELQELSSDISNTIASELSELQVVIIDEISMVSSTVFLWIDQRLREIFGTNAAFSGRHVLILGDFWQIPPVHDSPIYDPFKRDPSKRLRRFDIWHSFKVHYLTTIMQQRDDAAFAIALNNLAKGFRTEKHLSTAFDLIQGEGGTREARESLLTVAKDVNYPIGKTAGLSYELQLVIGAKYMVTSNIDIADGLVNGTTGVLKKVDVRHVTLDDGKVVTKPLRIWLQLDIGRPMSQLHQFFRRRKNSMLRISRTQFPLVVAETLTVRKSQGGTYXRDDAAFAIALNNLAKGVMNTTDIELLSSRTFKDLPTDAYHDGVNSVHLFATNKDVNNCEGGTREARESLLAVAKDVDYPISKTAGLSYELQLVIGAEYMVTSNIDIADGLVNGTTGVLRKVDVGHVTLNDGGVVTKPLRIWLQLDSERSGKEARGNHRAAALQADIPASWTPIDPVTTVFQRRKNSMLRISRTQFPLVVAESLTVHKSQGGTYRKVLLDLAGSRGAKNHTLTRSMMYVACSRSTSPQGLYIKCNHGFKPTLPPQADHPLVNEVLRYAAVKMVALFIHLREKQYQQLIVHNIKSFNAHFRIICKDPVYQVSDFILLTETGTTDTTPIDIDGFQVRARVNVEGQQPKPYGSLVAVSKSRLMSLEDFVPIEILKQTNDSSISVSGFTAQYISVLCIYKSPKADIYLLENLIESILLQKHGRRSIEQTESHISITS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7N9Y8</accession>
    <name>A0A1C7N9Y8_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="12">High osmolarity signaling protein sho1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">sho1_1</name>
        <name evidence="12" type="ORF">A0J61_06019</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SHO1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000344">
        <property type="protein sequence ID" value="OBZ85935.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7N9Y8"/>
    <dbReference type="STRING" id="101091.A0A1C7N9Y8"/>
    <dbReference type="InParanoid" id="A0A1C7N9Y8"/>
    <dbReference type="OrthoDB" id="5983572at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="CDD" id="cd11855">
        <property type="entry name" value="SH3_Sho1p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.40">
        <property type="entry name" value="SH3 Domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036028">
        <property type="entry name" value="SH3-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001452">
        <property type="entry name" value="SH3_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035522">
        <property type="entry name" value="Sho1_SH3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00018">
        <property type="entry name" value="SH3_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00452">
        <property type="entry name" value="SH3DOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00326">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50044">
        <property type="entry name" value="SH3-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50002">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 9" id="KW-0728">SH3 domain</keyword>
    <keyword evidence="7" id="KW-0346">Stress response</keyword>
    <keyword evidence="5 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="12"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="42"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="69"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="95"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="domain" description="SH3" evidence="11">
        <location>
            <begin position="190"/>
            <end position="257"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009739"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="OBZ85935.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="257" mass="27850" checksum="6D963C0F7A7298BC" modified="2016-11-30" version="1">MEEYNHTLTSPLIAITSALAAAAWLILFIGACVAAFHGVAWWIIIFELVVVVGTIVLLGINKFGPYRNMAYLLMAISLVYLTWLCQYTLDRNAEGGARAAAAGSVILIIVQFIWALELTAPGGGTRMSGGSWGAAGNGATNFGQRFTNAVRPAGGAHHGHHGHHNKNYNKELPRYGVNDEESIGDGSSVGDFEQATALHSCKELTHFLCLDQASAEDPNELSFSKNEVLDILDKRGNWWQARKQDGTTGIVPSNYFQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NAM3</accession>
    <name>A0A1C7NAM3_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">A0J61_06209</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. MFSD6 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000364">
        <property type="protein sequence ID" value="OBZ85749.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NAM3"/>
    <dbReference type="InParanoid" id="A0A1C7NAM3"/>
    <dbReference type="OrthoDB" id="515887at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024989">
        <property type="entry name" value="MFS_assoc_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051717">
        <property type="entry name" value="MFS_MFSD6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16172">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN 6-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16172:SF41">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN 6-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12832">
        <property type="entry name" value="MFS_1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="7"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="38"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="66"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="109"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="152"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="177"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="331"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="366"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="391"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="420"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="463"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="490"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="330"/>
            <end position="518"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OBZ85749.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="518" mass="56193" checksum="28920E6635C9BB3C" modified="2016-11-30" version="1">MYLICKLLYIAIFALLSAAPPYLPLYYSDVLHFSSDQIGLVLAIAPFVQSIACPLWSLVVDKRPRLHGAIMALTSFLGGSAIMGIMVIGHVASSSNLGAPIVFGISNTVLVTITSALALAFAFFTLPNMSLVDSAVMKILGPNKILYGEQRLWGSVSAGLSILLVGQLISFTSNYDMLFYVFGASTLVFMGLSFSVDVDAPQNQYVAAPELLNDSGLQHVPSYNNNLTTVPTSNDAEKLLNTRMPINNYSSIPSDQNNSANRYDLFKTDSIASAHTIREEADETLDTLGHIDLGLAISRIASIDQSLAGLREVTTGGIPPEAKSVFKSFRVITFLMTTLLFGVVLSIIINFLFLFLSRDLHMPASWIGWTGPTTGATELLCFCFSKQLTELFGVTNMILIAHIATIVRCLIYTILPSDSFFTNVSALLLQTLHGIGFGIFWATAVSEMDSFFPPEQRSVAQGILGALHFGLGTGLGALVGGYLFEYLGAIWMFRVAALVAAVNMCVFYIGRLDRFKLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-04-02" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NAT6</accession>
    <name>A0A1C7NAT6_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Mitogen-activated protein kinase-binding protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">Mapkbp1</name>
        <name evidence="5" type="ORF">A0J61_05731</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000318">
        <property type="protein sequence ID" value="OBZ86225.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NAT6"/>
    <dbReference type="InParanoid" id="A0A1C7NAT6"/>
    <dbReference type="OrthoDB" id="6252103at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011047">
        <property type="entry name" value="Quinoprotein_ADH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013979">
        <property type="entry name" value="TIF_beta_prop-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056162">
        <property type="entry name" value="WD40_MABP1-WDR62_2nd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052779">
        <property type="entry name" value="WDR62"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45589">
        <property type="entry name" value="WD REPEAT DOMAIN 62, ISOFORM G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45589:SF1">
        <property type="entry name" value="WD REPEAT DOMAIN 62, ISOFORM G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08662">
        <property type="entry name" value="eIF2A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24782">
        <property type="entry name" value="WD40_MABP1-WDR62_2nd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="12"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50998">
        <property type="entry name" value="Quinoprotein alcohol dehydrogenase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="Translation initiation factor beta propellor-like" evidence="3">
        <location>
            <begin position="166"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="domain" description="MABP1/WDR62 second WD40" evidence="4">
        <location>
            <begin position="470"/>
            <end position="853"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="1">
        <location>
            <begin position="665"/>
            <end position="693"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="975"/>
            <end position="1004"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1037"/>
            <end position="1076"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1108"/>
            <end position="1201"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1227"/>
            <end position="1469"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1049"/>
            <end position="1076"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1111"/>
            <end position="1121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1130"/>
            <end position="1142"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="1175"/>
            <end position="1201"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="1253"/>
            <end position="1265"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1279"/>
            <end position="1291"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1328"/>
            <end position="1338"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1342"/>
            <end position="1351"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1377"/>
            <end position="1389"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1420"/>
            <end position="1439"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1440"/>
            <end position="1449"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF08662"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF24782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OBZ86225.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="1557" mass="171878" checksum="E14FF0166896CD78" modified="2016-11-30" version="1">MEEQFPVNSGNVPPPSQSTNLLSHQLNYQPNFQNTNGGLRRKTKEAIKVSSKLKLERILGLTSTSSNTIDTANDLIAYAAGAVVVIYNHKRNKQIALLYPPATIQSTTNTPGNAALNSMSNINSQPSSAPMITPLSGVTNNLGNNDLVSSTQTNTNDDKKATPVGNRAKPISCLAFSPDGNYIAVGEMGHQPRIFIWNVKEKKLLRELRSHKFGVLALAFSPNMRYLVSIGFQHDGYLYVWDWKKGTKLAGNKVTSRVNAVSFAKDGSYFVTAGLRHVKFWYLDTRGRLPKRGNSVSRETQVLDGRSGILGVLRDANFVDVACDQGSTAGYTYFITDTGILCIFKEGRVIDKWVDLQVKGAYSIAVSPNYVICTCSEGVIRLFEPGTLKYVGILPKPHPLGIDVTTITSPDMIRSPDANTFYPDAVAMVYDANAHRLTCVYSDRSLYVWDIRDLKKIGKYRSFIFHSDCVWGVEPCPNIEREDNAIPLNSFATFSGDGTIRIWNLDNPIHNAASTSTSPISPQQLNHTFMSPSSSTAVGLHRRNIYSRELVKMLYVDPDAAEFAKLRSDFEHGEDNCPDFGIRSLKMSRDGHMMASGDRKGNLRVHDMNSWEMMTYQEAHDSEILSIDITTPKSEESPSLVATASRDRLLHVFDAKSKFQLVQSLDDHSSSITSVKFSEDASRLISCGADKGIIFRNRTHPVTLFHDNVPRPFSTYHNYSGRSTVFDMALDVSGRYVATVTGERKLYVFSVESGKPFRTCRPETSDEVGKSVENSGGSLINIDLDPFSGTYAVTSGSDRCIRLFDLTNSTCIEKVCAHSELITSIKFVRTNLEENGLRVVSTCSDGTIFVWKVGQEIIAKMTARASEREVKMKQRLLIDDDDLSDIDEKRALALGLQINKRIRRVSTVASIRPTASISQMIRQGERRTFSSMSPAEQKYDDLYKKIAASSNRRNNIDTNTIPHNSQLHVQTQLNENASHSGPVSPVGNRGSNTNRSLLSRREPRLTNNLAATDNQNNINNSKLPQDKVAKLDRLYNGVPTNGGRDRPSNHITSPVSITSQRNPLQPQQAPLSTIGNHNLISGNRHNQVLRRAMSKEGLRKVPATFTSATKQLPQQQQQQIQHQKEPSSLARKSSQPSLINNRRSSDPQAEAGGQEDDLCISESPKVISKPLLVEEGSDNDADVETGRDEADDIDDDDEEEEIEEEIIFTAEQDKIIKPFEVSMHLAPSSCEDEEEDGRITPVSDNENNHNKVDEEDDGSSEENVDDAINRAIVAREPPRVSVSISRTTSSVANSSRRRSGLLVDITKRLSAEAVTAPSSPPSDECESSSDSPSSPNNPAFREIQRNLEKAAKRQSLTARFLSSLGGPTKLSPDMQEQDSSLNHIMSSLQGVKPQAEEVVTTEALPPNKKVSLDKIEINTPIPSTSSHSNSEAEVPSSSEHTTKSSDKETPQNMSISNAVEDEKEEDSSKLENALADLEGIAILLDSVMDVYMSTTKTSKNEKTLSNIESKLTGVADRITQTMQNQSNIPKTSPETLDLLEKYSSLLIGMVGDKLRKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-06-18" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NB79</accession>
    <name>A0A1C7NB79_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Protein HID1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">Hid1</name>
        <name evidence="2" type="ORF">A0J61_05947</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000337">
        <property type="protein sequence ID" value="OBZ86009.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NB79"/>
    <dbReference type="FunCoup" id="A0A1C7NB79">
        <property type="interactions" value="8"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NB79"/>
    <dbReference type="InParanoid" id="A0A1C7NB79"/>
    <dbReference type="OrthoDB" id="432953at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005797">
        <property type="term" value="C:Golgi medial cisterna"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000138">
        <property type="term" value="C:Golgi trans cisterna"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026705">
        <property type="entry name" value="Hid-1/Ecm30"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21575">
        <property type="entry name" value="PROTEIN HID1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21575:SF12">
        <property type="entry name" value="PROTEIN HID1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12722">
        <property type="entry name" value="Hid1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="622"/>
            <end position="654"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="666"/>
            <end position="692"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="666"/>
            <end position="677"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="728"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OBZ86009.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="728" mass="83917" checksum="3E77BE56864A403E" modified="2016-11-30" version="1" fragment="single">MGAADSKLAFRKSVFKLYEEKTIPPTENEFWELFWNLPETIDDVFSLIGANDIRRTRDSAPDNFETLIDKVLKKMQDTVHANQFPTDQHSINHLLNCCRIMTRIMPFVFESPEHTEWEERFFWTPRQVEKEKKNPEDKPEYETLPCRGELLLDLTIQALFLAGFTIPIALATKESKVNYMIWENGVGSSLPITTYKDNEANRTEVLRLLVVLLSRSMYVLPSQLLLKEDLWLRYVAVKTERKIVLVILCSLLNTICNYDPTGWVPYNHVVGVGPREQLVTFCLTALLILLDYRSPQQAETMRQQEQLHSPTSHKSAELPAQVETLTLENPDAIPRTSMELEVFTPGTTDPYHHKVDENAFRHYMSKMHRKQDFEFLMLGIYRLLSNPMTAANTYLPGSTKRVSCFIDVVMLCWRLIETNPRFIKHLVETERALDLTVSLIFYAMDNKDKMTQIGLVRMCAFILQTLSSEKEYCVKLNKPFTTHASLPNVIRLYAFNGTYADFLIISIYTLISSTQGRLSALYPAFMLTIANISSYVSNLGVTTSSKLISMFHSMASPTFLLADEYNPQLTCYLLETLNNLIHYHYTENLNLVYAVVLHHDYFDRLSKLTFTDAVAEVNRVRQMRERKSAEDEHETTLEENKKDHEDHKEDEEKPKLSYAAVVASNLPSNEAGSSTSNPERRDSTNTISAYPTRQGFVPNEQWMSYWKSKFPLSTLSALIEQLVPKMEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-06-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NBF3</accession>
    <name>A0A1C7NBF3_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_05488</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000297">
        <property type="protein sequence ID" value="OBZ86462.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NBF3"/>
    <dbReference type="InParanoid" id="A0A1C7NBF3"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ86462.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="67" mass="7919" checksum="1BC9ED8D894F699C" modified="2016-11-30" version="1">MHVPCLVYPSTEELVISTEQKLRFVVDFYHSLYHPNRIHFNAIHILLDPVRSRLTPEQANDLMKPFT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2023-06-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NBH5</accession>
    <name>A0A1C7NBH5_9FUNG</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">A0J61_05468</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000295">
        <property type="protein sequence ID" value="OBZ86482.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NBH5"/>
    <dbReference type="InParanoid" id="A0A1C7NBH5"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OBZ86482.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="126" mass="14781" checksum="23CCB17920482FA2" modified="2016-11-30" version="1">MKKTETIDEFIQKFRYLSHVTEITNEAVLCELFVKALFNKLQQCFKVYLTLISETKGPDLSKAGVSIDFLMDLVRKAYYVFFTDEPIKHAGFKRPRPDHEECIFHPSTRMIHSTIDCRSLKKFKKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2025-02-05" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NCY2</accession>
    <name>A0A1C7NCY2_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Ras-GEF domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">A0J61_05340</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LUGH01000285">
        <property type="protein sequence ID" value="OBZ86609.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1C7NCY2"/>
    <dbReference type="STRING" id="101091.A0A1C7NCY2"/>
    <dbReference type="InParanoid" id="A0A1C7NCY2"/>
    <dbReference type="OrthoDB" id="10254377at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005085">
        <property type="term" value="F:guanyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007264">
        <property type="term" value="P:small GTPase-mediated signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.840.10">
        <property type="entry name" value="Ras guanine-nucleotide exchange factors catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023578">
        <property type="entry name" value="Ras_GEF_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001895">
        <property type="entry name" value="RASGEF_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036964">
        <property type="entry name" value="RASGEF_cat_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00617">
        <property type="entry name" value="RasGEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00147">
        <property type="entry name" value="RasGEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48366">
        <property type="entry name" value="Ras GEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50009">
        <property type="entry name" value="RASGEF_CAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0344">Guanine-nucleotide releasing factor</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ras-GEF" evidence="3">
        <location>
            <begin position="98"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="472"/>
            <end position="714"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="747"/>
            <end position="786"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="11"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="474"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="503"/>
            <end position="521"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="548"/>
            <end position="557"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="564"/>
            <end position="582"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="583"/>
            <end position="600"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="671"/>
            <end position="685"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="694"/>
            <end position="706"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="770"/>
            <end position="786"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00168"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50009"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OBZ86609.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000093000"/>
        </source>
    </evidence>
    <sequence length="786" mass="88461" checksum="E4075C75124A23B2" modified="2016-11-30" version="1">MATKAAIQDAPHSSSPHHINNQSLPSIPLSPIAQSYIISFKELNQVNEKLAEAKRADPPVPVASLRGLIETSKIEERRLSSLLLKMQSLEAATPLYWDANTLARQIAVTNCQLFNQVFLDKRSLSQVDLNRTKLVHLVDFHHYLSHSMAHQLVYWVELLNNPEAASAVVPLPTKDSLVAHLVRVAYLLLHAYRDFSGLAAIMKALTFPEVRRLNKKLWTGANSRTKDMFRDLAQIISPTRNYQVYHHALRSKLDTKSSSAAMMAIPWIHPHLLSIRSIVSAYTAGDNEDLHHLSGDIVLSAPGAHKLDLELALMELCQQNSPTGDFTTEDILSTHGYEVKPSRRGSTVMGSNSNNKAIHIEGLRSAVLPVANLNHLAPGDEHTQHWLVSRVYLRKDQLINESIEVEPLKPGETISCEEDVEETPVRHLPPILSNTISRRASIAQPQTRTASILDISEESVFMEQRLINTVQHLNQEERDKKDEEEIPAGTKHDLSSISNRVIDEEDEEEVEQAVREDEEEVQIVTEPPATDATVENNDLTEPVSEEEALIKSVREHNVTPPVGQEDKSVQEDPKPTKQENRHLSASTTESTRQANKSKLSPTAPVFVPNKILSVKKTGSVATNTTDEWLGYPIKEEEEAATVGSTSDSEKWVGYPAPVTDEDDDKVVLSEDHDDDDDDDDDDDEEVWKGYPGPNNHNPRRASSQSETSEEWKGYHATKMEADWQRESALKVQEHEWQGYALETLDEDELDSSTMMDGEFEKSRQARGHQRQHDKDQVIENFRRKRH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-11-30" modified="2026-01-28" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1C7NE21</accession>
    <name>A0A1C7NE21_9FUNG</name>
    <protein>
        <recommendedName>
            <fullName evidence="18">Phospholipid-transporting ATPase</fullName>
            <ecNumber evidence="18">7.6.2.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="22" type="primary">Atp10d</name>
        <name evidence="22" type="ORF">A0J61_06336</name>
    </gene>
    <organism evidence="22 23">
        <name type="scientific">Choanephora cucurbitarum</name>
        <dbReference type="NCBI Taxonomy" id="101091"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Fungi</taxon>
            <taxon>Fungi incertae sedis</taxon>
            <taxon>Mucoromycota</taxon>
            <taxon>Mucoromycotina</taxon>
            <taxon>Mucoromycetes</taxon>
            <taxon>Mucorales</taxon>
            <taxon>Mucorineae</taxon>
            <taxon>Choanephoraceae</taxon>
            <taxon>Choanephoroideae</taxon>
            <taxon>Choanephora</taxon>
        </lineage>
    </organism>
    <reference evidence="22 23" key="1">
        <citation type="submission" date="2016-03" db="EMBL/GenBank/DDBJ databases">
            <title>Choanephora cucurbitarum.</title>
            <authorList>
                <person name="Min B."/>
                <person name="Park H."/>
                <person name="Park J.-H."/>
                <person name="Shin H.-D."/>
                <person name="Choi I.-G."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="22 23">KUS-F28377</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="13 18">
            <text>ATP + H2O + phospholipidSide 1 = ADP + phosphate + phospholipidSide 2.</text>
            <dbReference type="EC" id="7.6.2.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>a 1,2-diacyl-sn-glycero-3-phosphoethanolamine(out) + ATP + H2O = a 1,2-diacyl-sn-glycero-3-phosphoethanolamine(in) + ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:66132"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:64612"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="14">
            <dbReference type="Rhea" id="RHEA:66133"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="17">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="18">Membrane</location>
            <topology evidence="18">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 18">Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="22">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="7.6.2.1" evidence="18"/>
    <dbReference type="EMBL" id="LUGH01000378">
        <property type="protein sequence ID" value="OBZ85614.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="101091.A0A1C7NE21"/>
    <dbReference type="InParanoid" id="A0A1C7NE21"/>
    <dbReference type="OrthoDB" id="377733at2759"/>
    <dbReference type="Proteomes" id="UP000093000">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140326">
        <property type="term" value="F:ATPase-coupled intramembrane lipid transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045332">
        <property type="term" value="P:phospholipid translocation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.1110.10:FF:000087">
        <property type="entry name" value="Phospholipid-transporting ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1000:FF:000014">
        <property type="entry name" value="Phospholipid-transporting ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic domain N"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.150.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic transduction domain A"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, transmembrane domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023299">
        <property type="entry name" value="ATPase_P-typ_cyto_dom_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018303">
        <property type="entry name" value="ATPase_P-typ_P_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023298">
        <property type="entry name" value="ATPase_P-typ_TM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008250">
        <property type="entry name" value="ATPase_P-typ_transduc_dom_A_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006539">
        <property type="entry name" value="P-type_ATPase_IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032631">
        <property type="entry name" value="P-type_ATPase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001757">
        <property type="entry name" value="P_typ_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032630">
        <property type="entry name" value="P_typ_ATPase_c"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044492">
        <property type="entry name" value="P_typ_ATPase_HD_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01652">
        <property type="entry name" value="ATPase-Plipid"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01494">
        <property type="entry name" value="ATPase_P-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24092:SF180">
        <property type="entry name" value="PHOSPHOLIPID-TRANSPORTING ATPASE DNF1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24092">
        <property type="entry name" value="PROBABLE PHOSPHOLIPID-TRANSPORTING ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13246">
        <property type="entry name" value="Cation_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16212">
        <property type="entry name" value="PhoLip_ATPase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16209">
        <property type="entry name" value="PhoLip_ATPase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00119">
        <property type="entry name" value="CATATPASE"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG00002">
        <property type="entry name" value="C1.7:_P-type_atpase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00003">
        <property type="entry name" value="Haloacid_Dehalogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00027">
        <property type="entry name" value="p-type_atpase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81653">
        <property type="entry name" value="Calcium ATPase, transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81665">
        <property type="entry name" value="Calcium ATPase, transmembrane domain M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81660">
        <property type="entry name" value="Metal cation-transporting ATPase, ATP-binding domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00154">
        <property type="entry name" value="ATPASE_E1_E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 16 18" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9 17 18" id="KW-0460">Magnesium</keyword>
    <keyword evidence="12 18" id="KW-0472">Membrane</keyword>
    <keyword evidence="6 17" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 16 18" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="23" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10 18" id="KW-1278">Translocase</keyword>
    <keyword evidence="5 18" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="11 18" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="392"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="1147"/>
            <end position="1166"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="1229"/>
            <end position="1252"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="1264"/>
            <end position="1284"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="1296"/>
            <end position="1316"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="1322"/>
            <end position="1347"/>
        </location>
    </feature>
    <feature type="domain" description="P-type ATPase N-terminal" evidence="20">
        <location>
            <begin position="90"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="domain" description="P-type ATPase C-terminal" evidence="21">
        <location>
            <begin position="1115"/>
            <end position="1362"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="19">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="19">
        <location>
            <begin position="532"/>
            <end position="574"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="19">
   
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